single cell Hi-C normalization

SCL: A lattice-based approach to infer three-dimensional chromosome structures from single-cell Hi-C data

SCL (Single-Cell Lattice) is a computational method to reconstruct high-resolution 3D chromosome structures based on the zero-inflated single-cell Hi-C data.


The C++ source code and a user manual of SCL can be downloaded from here.


Zhu,H. and Wang,Z. (2019) SCL: a lattice-based approach to infer 3D chromosome structures from single-cell Hi-C data. Bioinformatics, in press.


For any questions or suggestions, please contact:
Dr. Zheng Wang
Department of Computer Science
University of Miami