BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9ZQI7 (456 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4FL0-A nrPDB 941 0.0 3EI8-A nrPDB 533 e-152 3QGU-A nrPDB 474 e-134 3ASB-A nrPDB 308 5e-84 2X5D-A nrPDB 115 3e-26 1GDE-A nrPDB 103 2e-22 1O4S-A nrPDB 93 2e-19 2Z61-A nrPDB 93 2e-19 1V2E-A nrPDB 92 4e-19 5YHV-A nrPDB 89 6e-18 1J32-A nrPDB 88 7e-18 1GC4-A nrPDB 85 8e-17 2O1B-A nrPDB 82 6e-16 5WMH-A nrPDB 81 1e-15 4MY5-A nrPDB 77 1e-14 1XI9-A nrPDB 75 5e-14 6F35-A nrPDB 70 2e-12 4CVQ-A nrPDB 70 3e-12 3H14-A nrPDB 69 3e-12 3ELE-A nrPDB 67 2e-11 6F77-B nrPDB 63 3e-10 3EZS-A nrPDB 62 4e-10 1U08-A nrPDB 62 5e-10 4WP0-A nrPDB 61 1e-09 3OP7-A nrPDB 60 2e-09 3FVS-A nrPDB 60 2e-09 3JTX-A nrPDB 60 3e-09 4M2J-A nrPDB 59 6e-09 1LC8-A nrPDB 57 2e-08 2DOU-A nrPDB 56 3e-08 2ZJG-A nrPDB 56 4e-08 4R2N-A nrPDB 53 3e-07 3FFH-A nrPDB 51 1e-06 3DZZ-A nrPDB 51 1e-06 2O0R-A nrPDB 50 2e-06 3T32-A nrPDB 50 3e-06 1YIY-A nrPDB 48 8e-06 3B46-A nrPDB 48 8e-06 4RAE-A nrPDB 47 2e-05 6C3C-A nrPDB 47 2e-05 4DQ6-A nrPDB 47 2e-05 1BW0-A nrPDB 47 2e-05 3LY1-A nrPDB 46 3e-05 2HOR-A nrPDB 46 4e-05 4IX8-A nrPDB 45 6e-05 2ZYJ-A nrPDB 45 6e-05 3DYD-A nrPDB 45 9e-05 3CQ5-A nrPDB 44 1e-04 1IJI-A nrPDB 44 1e-04 3FKD-A nrPDB 44 1e-04 3PDX-A nrPDB 44 2e-04 3FDB-A nrPDB 43 2e-04 3GET-A nrPDB 43 3e-04 3B1C-A nrPDB 42 5e-04 1UU1-A nrPDB 42 5e-04 3FTB-A nrPDB 42 5e-04 1M4N-A nrPDB 42 8e-04 1YAA-A nrPDB 41 0.001 5DJ3-A nrPDB 40 0.002 3AV7-A nrPDB 40 0.002 3P1T-A nrPDB 40 0.002 1X0M-A nrPDB 40 0.002 3L8A-A nrPDB 40 0.002 6EZL-A nrPDB 40 0.003 3TCM-A nrPDB 40 0.003 2ZC0-A nrPDB 39 0.007 3MEB-A nrPDB 38 0.008 2ZY3-A nrPDB 38 0.009 1D2F-A nrPDB 38 0.010 1IAY-A nrPDB 37 0.019 1TAR-A nrPDB 37 0.025 3NRA-A nrPDB 37 0.026 3VK2-A nrPDB 36 0.027 1VP4-A nrPDB 36 0.031 3E9A-A nrPDB 36 0.040 5Z0Q-C nrPDB 35 0.089 2ZY2-A nrPDB 34 0.12 3IF2-A nrPDB 34 0.13 1AY8-A nrPDB 34 0.14 1C7O-A nrPDB 34 0.16 1KNR-A nrPDB 33 0.21 3G7Q-A nrPDB 33 0.24 3PD6-B nrPDB 33 0.25 3IHJ-A nrPDB 33 0.25 3F6T-A nrPDB 33 0.25 3FDD-A nrPDB 33 0.26 3BWN-A nrPDB 33 0.27 3K7Y-A nrPDB 33 0.33 3II0-A nrPDB 33 0.34 3EUC-A nrPDB 33 0.37 2X5F-A nrPDB 32 0.45 3G0T-A nrPDB 32 0.47 4WBT-A nrPDB 32 0.84 3U14-A nrPDB 31 0.86 1WST-A nrPDB 31 0.92 5TON-A nrPDB 31 0.94 4WB0-B nrPDB 31 0.98 4F5M-A nrPDB 31 1.1 5EJ0-A nrPDB 31 1.3 4RKC-A nrPDB 30 1.5 4H51-A nrPDB 30 1.8 4WD2-A nrPDB 30 1.9 1GG0-A nrPDB 30 2.5 1FOK-A nrPDB 29 3.9 3RQ1-A nrPDB 29 4.4 1H0O-A nrPDB 29 4.9 3MKJ-A nrPDB 29 5.0 3STG-A nrPDB 29 5.1 4BUC-A nrPDB 28 7.6 2A21-A nrPDB 28 9.7 >4FL0-A nrPDB Length = 456 Score = 941 bits (2433), Expect = 0.0, Method: Compositional matrix adjust. Identities = 456/456 (100%), Positives = 456/456 (100%) Query: 1 MVSLMFFSSASPLCSSPSKIPKASLDFEMKKLGGSTKLVRNVNLEKLKNNYLFPEINRRE 60 MVSLMFFSSASPLCSSPSKIPKASLDFEMKKLGGSTKLVRNVNLEKLKNNYLFPEINRRE Sbjct: 1 MVSLMFFSSASPLCSSPSKIPKASLDFEMKKLGGSTKLVRNVNLEKLKNNYLFPEINRRE 60 Query: 61 LEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKA 120 LEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKA Sbjct: 61 LEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKA 120 Query: 121 IAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTG 180 IAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTG Sbjct: 121 IAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTG 180 Query: 181 HFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDF 240 HFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDF Sbjct: 181 HFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDF 240 Query: 241 AKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPD 300 AKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPD Sbjct: 241 AKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPD 300 Query: 301 ELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILM 360 ELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILM Sbjct: 301 ELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILM 360 Query: 361 DTLVSLGLKVYGGVNAPYLWVHFKGSKSWDVFNEILENTHIITVPGSGFGPGGEEYLRIS 420 DTLVSLGLKVYGGVNAPYLWVHFKGSKSWDVFNEILENTHIITVPGSGFGPGGEEYLRIS Sbjct: 361 DTLVSLGLKVYGGVNAPYLWVHFKGSKSWDVFNEILENTHIITVPGSGFGPGGEEYLRIS 420 Query: 421 GFGRRDHIVEASKRLQNFFNTRTKHFTYLSSTSNTN 456 GFGRRDHIVEASKRLQNFFNTRTKHFTYLSSTSNTN Sbjct: 421 GFGRRDHIVEASKRLQNFFNTRTKHFTYLSSTSNTN 456 >3EI8-A nrPDB Length = 432 Score = 533 bits (1372), Expect = e-152, Method: Compositional matrix adjust. Identities = 256/410 (62%), Positives = 321/410 (78%) Query: 30 KKLGGSTKLVRNVNLEKLKNNYLFPEINRRELEHIEKHPNVQLISLGTGDTTEPIPEQIT 89 +K+ TK+ RN N+ KL+ YLFPEI RR H+ K+P+ Q+ISLG GDTTEPIPE IT Sbjct: 16 EKIEYKTKVSRNSNMSKLQAGYLFPEIARRRSAHLLKYPDAQVISLGIGDTTEPIPEVIT 75 Query: 90 SHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRL 149 S M+ AH LST+EGY GYG EQG K LR AIA+TFY L + ++VFVSDGA+ DISRL Sbjct: 76 SAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDISRL 135 Query: 150 QLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAM 209 Q++ GSNVTIAVQDP++PAY+DSSVI+GQTG F+ +KY N+ YM C P N FFPDL+ Sbjct: 136 QVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLST 195 Query: 210 TPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEI 269 RTD+IFFCSPNNPTG A+R+QL QLV+FAK NGSII++DSAYA ++ D +PRSI+EI Sbjct: 196 VGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEI 255 Query: 270 PGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIA 329 PGA EVA+E +SFS +AGFTGVRLGW++IP +LLYS+GFP+ DF+RI+ T FNGASNI+ Sbjct: 256 PGAEEVAMETASFSNYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNIS 315 Query: 330 QAGGLACLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSW 389 QAG LACL+ GL+ + V +YKEN I++DT SLG VYGG NAPY+WVHF SW Sbjct: 316 QAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSW 375 Query: 390 DVFNEILENTHIITVPGSGFGPGGEEYLRISGFGRRDHIVEASKRLQNFF 439 DVF EILE TH++T PGSGFGPGGE ++R+S FG R++I+EA +R + + Sbjct: 376 DVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQLY 425 >3QGU-A nrPDB Length = 449 Score = 474 bits (1220), Expect = e-134, Method: Compositional matrix adjust. Identities = 223/415 (53%), Positives = 301/415 (72%), Gaps = 3/415 (0%) Query: 29 MKKLGGSTKLVRNVNLEKLKNNYLFPEINRRELEHIEKHPNVQLISLGTGDTTEPIPEQI 88 + + G+ + RN N KL+ YLFPEI RR H EK+P+ ++ISLG GDTTEP+P+ I Sbjct: 28 VAQRAGTIDVQRNENFGKLRAGYLFPEIARRRKAHQEKNPDAKIISLGIGDTTEPLPKYI 87 Query: 89 TSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISR 148 M+ A GL+T EGY GYG EQG LR+A+A TFY ++E+F+SDG++ DI+R Sbjct: 88 ADAMAKAAAGLATREGYSGYGAEQGQGALREAVASTFYGHAGRAADEIFISDGSKCDIAR 147 Query: 149 LQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLA 208 +Q++ GS T+AVQDP++P Y+D+SV++G TG H T + + YM C P+N FFPDL+ Sbjct: 148 IQMMFGSKPTVAVQDPSYPVYVDTSVMMGMTGD-HNGTG-FDGIEYMVCNPDNHFFPDLS 205 Query: 209 MTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIED-GSPRSIY 267 RTD+IFFCSPNNPTG A+R QL +LV+FA+ NGSI+++D+AYA +I + P++IY Sbjct: 206 KAKRTDIIFFCSPNNPTGAAATRAQLTELVNFARKNGSILVYDAAYALYISNPDCPKTIY 265 Query: 268 EIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASN 327 EIPGA EVAIE SFSK+AGFTGVRLGW+++P L Y+NG P+ D++R++TT FNGASN Sbjct: 266 EIPGADEVAIETCSFSKYAGFTGVRLGWTVVPKALKYANGEPVHADWNRVMTTCFNGASN 325 Query: 328 IAQAGGLACLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFKGSK 387 I QAGGLACL GLKE+ ++ +YKEN +IL T +G VYGG +APY+WV F G Sbjct: 326 IVQAGGLACLQPEGLKEMNAMIKFYKENAQILKTTFTEMGFSVYGGDDAPYIWVGFPGKP 385 Query: 388 SWDVFNEILENTHIITVPGSGFGPGGEEYLRISGFGRRDHIVEASKRLQNFFNTR 442 SWDVF EILE +I+T PGSG+GP GE ++R S FG R++I+EA +R + + R Sbjct: 386 SWDVFAEILERCNIVTTPGSGYGPAGEGFVRASAFGSRENILEAVRRFKEAYGKR 440 >3ASB-A nrPDB Length = 400 Score = 308 bits (788), Expect = 5e-84, Method: Compositional matrix adjust. Identities = 160/400 (40%), Positives = 244/400 (61%), Gaps = 18/400 (4%) Query: 40 RNVNLEKLKNNYLFPEINRRELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGL 99 RN + L NYLF ++ +R + ++P +I+L GDTT+P+ + ++ L Sbjct: 3 RNPHFVSLTKNYLFADLQKRVAQFRLENPQHTVINLSIGDTTQPLNASVAEAFASSIARL 62 Query: 100 STVEGYRGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTI 159 S+ RGYG + G LR+ ++E FYR V + E+F+SDGA+ D+ RL G N T+ Sbjct: 63 SSPTTCRGYGPDFGLPALRQKLSEDFYRGF-VDAKEIFISDGAKVDLFRLLSFFGPNQTV 121 Query: 160 AVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFC 219 A+QDP++PAY+D + + G + ++ +PC N+FFP+ D++ C Sbjct: 122 AIQDPSYPAYLDIARLTGA-----------KEIIALPCLQENAFFPEFPEDTHIDILCLC 170 Query: 220 SPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGS-PRSIYEIPGAREVAIE 278 SPNNPTG V ++ QL +V +A + +I+FD+AY+ FI D S P+SI+EIP AR AIE Sbjct: 171 SPNNPTGTVLNKDQLRAIVHYAIEHEILILFDAAYSTFISDPSLPKSIFEIPDARFCAIE 230 Query: 279 VSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLS 338 ++SFSK GF G+RLGW++IP EL Y++G +I D+ R ++T+FNGAS AQ G+A LS Sbjct: 231 INSFSKPLGFAGIRLGWTVIPQELTYADGHFVIQDWERFLSTTFNGASIPAQEAGVAGLS 290 Query: 339 SGGLKEIRSVNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFKGS--KSWDVFNEIL 396 L ++ ++ +YY+EN +L L++ G +V+GG +APYLWV + D+F+ L Sbjct: 291 I--LPQLEAI-HYYRENSDLLRKALLATGFEVFGGEHAPYLWVKPTQANISDRDLFDFFL 347 Query: 397 ENTHIITVPGSGFGPGGEEYLRISGFGRRDHIVEASKRLQ 436 HI PG GFG G ++R S G+R+ I+ A +RLQ Sbjct: 348 REYHIAITPGIGFGRSGSGFVRFSSLGKREDILAACERLQ 387 >2X5D-A nrPDB Length = 412 Score = 115 bits (289), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 98/397 (24%), Positives = 171/397 (43%), Gaps = 41/397 (10%) Query: 60 ELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRK 119 EL+ + +I L G+ P P I + A E GY +G LR+ Sbjct: 27 ELKMAARRRGEDIIDLSMGNPDGPTPPHIVEKLCTVAQR----EDTHGYSTSRGIPRLRR 82 Query: 120 AIAETFYRDLHV----KSNEVFVSDGAQSDISRLQLL-LGSNVTIAVQDPTFPAYIDSSV 174 AI+ +YRD + +E V+ G++ ++ L L L TI V +P++P +I +V Sbjct: 83 AISH-WYRDRYDVQIDPESEAIVTIGSKEGLAHLMLATLDHGDTILVPNPSYPIHIYGAV 141 Query: 175 IIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMT-----PRTDVIFFCSPNNPTGYVA 229 I G V +P P FF +L P+ ++ P+NPT Sbjct: 142 IAGA------------QVRSVPLVPGIDFFNELERAIRESIPKPRMMILGFPSNPTAQCV 189 Query: 230 SRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDG-SPRSIYEIPGAREVAIEVSSFSKFAGF 288 ++V AK +++ D AYA + DG SI ++PGA+++A+E + SK Sbjct: 190 ELDFFERVVALAKQYDVMVVHDLAYADIVYDGWKAPSIMQVPGAKDIAVEFFTLSKSYNM 249 Query: 289 TGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSV 348 G R+G+ + EL ++ RI + G Q +A L G + +R + Sbjct: 250 AGWRIGFMVGNPEL--------VSALARIKSYHDYGTFTPLQVAAIAAL-EGDQQCVRDI 300 Query: 349 NNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVH----FKGSKSWDVFNEILENTHIITV 404 Y++ R +L+ L G V + Y+W + S + ++L++ + Sbjct: 301 ARQYQQRRDVLVKGLREAGWMVENPKASMYVWAKIPEPYAHLGSLEFAKKLLQDAKVSVS 360 Query: 405 PGSGFGPGGEEYLRISGFGRRDHIVEASKRLQNFFNT 441 PG GFG G++++R + RD + +A + ++ F Sbjct: 361 PGIGFGDYGDDHVRFALIENRDRLRQAVRGIKAMFRA 397 >1GDE-A nrPDB Length = 389 Score = 103 bits (256), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 100/387 (25%), Positives = 158/387 (40%), Gaps = 44/387 (11%) Query: 72 LISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYRDLHV 131 +ISLG G+ P+ I + + +G YG G LR+AIAE + + Sbjct: 28 VISLGIGEPDFDTPQHIKEYAKE-----ALDKGLTHYGPNIGLLELREAIAEKLKKQNGI 82 Query: 132 KSN---EVFVSDGA-QSDISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTK 187 +++ E+ V GA Q+ + L L + + P F +Y + ++ G Sbjct: 83 EADPKTEIMVLLGANQAFLMGLSAFLKDGEEVLIPTPAFVSYAPAVILAGG--------- 133 Query: 188 KYQNVVYMPCGPNNSFFPDLA-----MTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAK 242 V +P + F ++ +T +T + SP NPTG V ++K L ++ DF Sbjct: 134 ---KPVEVPTYEEDEFRLNVDELKKYVTDKTRALIINSPCNPTGAVLTKKDLEEIADFVV 190 Query: 243 TNGSIIIFDSAYAAFI-EDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDE 301 + I+I D Y FI +D SI + G E I V+ FSK TG RLG+ P Sbjct: 191 EHDLIVISDEVYEHFIYDDARHYSIASLDGMFERTITVNGFSKTFAMTGWRLGFVAAPSW 250 Query: 302 LLYSNGFPIINDFHRIVTTSFNGASN----IAQAGGLACLSSGGLKEIRSVNNYYKENRK 357 ++ R+V A+ I A A K + + Y RK Sbjct: 251 II-----------ERMVKFQMYNATCPVTFIQYAAAKALKDERSWKAVEEMRKEYDRRRK 299 Query: 358 ILMDTLVSLGLKVYGGVNAPYLWVHFK--GSKSWDVFNEILENTHIITVPGSGFGPGGEE 415 ++ L +GL A Y++ + G S +L+ + VPGS FG GE Sbjct: 300 LVWKRLNEMGLPTVKPKGAFYIFPRIRDTGLTSKKFSELMLKEARVAVVPGSAFGKAGEG 359 Query: 416 YLRISGFGRRDHIVEASKRLQNFFNTR 442 Y+RIS + + EA R++ R Sbjct: 360 YVRISYATAYEKLEEAMDRMERVLKER 386 >1O4S-A nrPDB Length = 389 Score = 93.2 bits (230), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 102/398 (25%), Positives = 176/398 (44%), Gaps = 46/398 (11%) Query: 55 EINRRELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAH-GLSTVEGYRG-YGLEQ 112 E++ + I+K +V I+L G+ P PE + F G RG Y L + Sbjct: 28 ELDAKAKALIKKGEDV--INLTAGEPDFPTPEPVVEEAVRFLQKGEVKYTDPRGIYELRE 85 Query: 113 GNKTLRKAIAETFYRDLHVKSNEVFVSDGA-QSDISRLQLLLGSNVTIAVQDPTFPAYID 171 G + K I E + +D + ++V V++GA Q+ + LL + V P + +YI Sbjct: 86 G---IAKRIGERYKKD--ISPDQVVVTNGAKQALFNAFMALLDPGDEVIVFSPVWVSYIP 140 Query: 172 SSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLA-----MTPRTDVIFFCSPNNPTG 226 ++ G T + E +M + +F P L + +T + SPNNPTG Sbjct: 141 QIILAGGTVNVVE--------TFM----SKNFQPSLEEVEGLLVGKTKAVLINSPNNPTG 188 Query: 227 YVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFA 286 V R+ L LV AK II D Y + + SI ++ + + ++ FSK Sbjct: 189 VVYRREFLEGLVRLAKKRNFYIISDEVYDSLVYTDEFTSILDVSEGFDRIVYINGFSKSH 248 Query: 287 GFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIR 346 TG R+G+ I ++ + +I + + + + +AQ L L ++ Sbjct: 249 SMTGWRVGYLISSEK--------VATAVSKIQSHTTSCINTVAQYAALKALEVDNSYMVQ 300 Query: 347 SVNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSWDV-FNE-ILENTHIITV 404 + +KE + +++ L +G+K A YL+ +G DV F E +LE + V Sbjct: 301 T----FKERKNFVVERLKKMGVKFVEPEGAFYLFFKVRGD---DVKFCERLLEEKKVALV 353 Query: 405 PGSGFGPGGEEYLRISGFGRRDHIVEASKRLQNFFNTR 442 PGS F G ++R+S + + EA R+++F N+R Sbjct: 354 PGSAFLKPG--FVRLSFATSIERLTEALDRIEDFLNSR 389 >2Z61-A nrPDB Length = 370 Score = 93.2 bits (230), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 84/345 (24%), Positives = 148/345 (42%), Gaps = 33/345 (9%) Query: 100 STVEGYRGYGLEQGNKTLRKAIAETFYRDLH---VKSNEVFVSDGAQSDIS-RLQLLLGS 155 S EG Y +G LR+ I+E Y+D + + + + ++ G+ + L ++ Sbjct: 54 SLKEGKTHYTDSRGILELREKISE-LYKDKYKADIIPDNIIITGGSSLGLFFALSSIIDD 112 Query: 156 NVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDV 215 + +Q+P +P Y + +G F + T + + A++ +T Sbjct: 113 GDEVLIQNPCYPCYKNFIRFLGAKPVFCDFTVESL---------------EEALSDKTKA 157 Query: 216 IFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREV 275 I SP+NP G V R ++ +FA N II D Y + +G S E E Sbjct: 158 IIINSPSNPLGEVIDR----EIYEFAYENIPYIISDEIYNGLVYEGKCYSAIEFDENLEK 213 Query: 276 AIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLA 335 I ++ FSK TG R+G+ I DE II ++ F A I+Q L Sbjct: 214 TILINGFSKLYAMTGWRIGYVISNDE--------IIEAILKLQQNLFISAPTISQYAALK 265 Query: 336 CLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSWDVFNEI 395 +EI S+ + R++++ + G +V + A Y++ + G + ++ Sbjct: 266 AFEKETEREINSMIKEFDRRRRLVLKYVKDFGWEVNNPIGAYYVFPNI-GEDGREFAYKL 324 Query: 396 LENTHIITVPGSGFGPGGEEYLRISGFGRRDHIVEASKRLQNFFN 440 L+ + PG GFG G+ Y+RIS ++I E +R++ F N Sbjct: 325 LKEKFVALTPGIGFGSKGKNYIRISYANSYENIKEGLERIKEFLN 369 >1V2E-A nrPDB Length = 381 Score = 92.0 bits (227), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 85/311 (27%), Positives = 128/311 (41%), Gaps = 40/311 (12%) Query: 108 YGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDI-SRLQLLLGSNVTIAVQDPTF 166 Y G LR+A+AE F V+ V V+ GA + LQ L+G + V +P F Sbjct: 57 YAPPAGLPALREALAEEF----AVEPESVVVTSGATEALYVLLQSLVGPGDEVVVLEPFF 112 Query: 167 PAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDL-----AMTPRTDVIFFCSP 221 Y+ + + G +V + P F DL A+TPRT + +P Sbjct: 113 DVYLPDAFLAGAKAR----------LVRLDLTPEG-FRLDLSALEKALTPRTRALLLNTP 161 Query: 222 NNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSS 281 NPTG V ++L + A+ + +I D Y PR + E A E V S Sbjct: 162 MNPTGLVFGERELEAIARLARAHDLFLISDEVYDELYYGERPRRLREF--APERTFTVGS 219 Query: 282 FSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAG---GLACLS 338 K TG R+GW + P E + P + + TSF+ + + QAG L Sbjct: 220 AGKRLEATGYRVGWIVGPKEFM-----PRLAGMRQ--WTSFSAPTPL-QAGVAEALKLAR 271 Query: 339 SGGLKEIRSVNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSWDVFNEILEN 398 G E ++ Y+ R +L L ++GL+VY +L G WD F ++E Sbjct: 272 REGFYE--ALREGYRRRRDLLAGGLRAMGLRVYVPEGTYFLMAELPG---WDAFR-LVEE 325 Query: 399 THIITVPGSGF 409 + +P S F Sbjct: 326 ARVALIPASAF 336 >5YHV-A nrPDB Length = 394 Score = 88.6 bits (218), Expect = 6e-18, Method: Compositional matrix adjust. Identities = 91/384 (23%), Positives = 161/384 (41%), Gaps = 39/384 (10%) Query: 71 QLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYR--D 128 L++L G + PE + + + H L+ + GY + G LR AIA + R Sbjct: 38 DLVNLSAGQPSAGAPEPVRAAAAAALH-LNQL----GYSVALGIPELRDAIAADYQRRHG 92 Query: 129 LHVKSNEVFVSDGAQSD-ISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTK 187 + V+ + V ++ G+ + + +A+ P +P Y + I+ G Sbjct: 93 ITVEPDAVVITTGSSGGFLLAFLACFDAGDRVAMASPGYPCYRN---ILSALGC------ 143 Query: 188 KYQNVVYMPCGPNNSFFPDLAMTPRTDV----IFFCSPNNPTGYVASRKQLHQLVDFAKT 243 VV +PCGP F P M D + SP NPTG V ++L + + Sbjct: 144 ---EVVEIPCGPQTRFQPTAQMLAEIDPPLRGVVVASPANPTGTVIPPEELAAIASWCDA 200 Query: 244 NGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELL 303 + +I D Y + G+P++ +R A+ V+SFSK+ TG RLGW ++P Sbjct: 201 SDVRLISDEVYHGLVYQGAPQTSCAWQTSRN-AVVVNSFSKYYAMTGWRLGWLLVPT--- 256 Query: 304 YSNGFPIINDFHRIVTTSFNGASNI-AQAGGLACLSSGGLKEIRSVNNYYKENRKILMDT 362 ++ +T +F + +Q ++ + E Y NR +L+D Sbjct: 257 ------VLRRAVDCLTGNFTICPPVLSQIAAVSAFTPEATAEADGNLASYAINRSLLLDG 310 Query: 363 LVSLGLKVYGGVN-APYLWVHFKG--SKSWDVFNEILENTHIITVPGSGFGPG-GEEYLR 418 L +G+ + A Y++ S S +++L +T + PG F G ++R Sbjct: 311 LRRIGIDRLAPTDGAFYVYADVSDFTSDSLAFCSKLLADTGVAIAPGIDFDTARGGSFVR 370 Query: 419 ISGFGRRDHIVEASKRLQNFFNTR 442 IS G I EA +R+ ++ ++ Sbjct: 371 ISFAGPSGDIEEALRRIGSWLPSQ 394 >1J32-A nrPDB Length = 388 Score = 88.2 bits (217), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 91/350 (26%), Positives = 156/350 (44%), Gaps = 34/350 (9%) Query: 103 EGYRGYGLEQGNKTLRKAIAETFYRD--LHVKSNEVFVSDGAQSDISRLQLLL---GSNV 157 +G YG G LR+AIA+ RD L ++ + V++G + I L L + G V Sbjct: 58 QGKTRYGPAAGEPRLREAIAQKLQRDNGLCYGADNILVTNGGKQSIFNLMLAMIEPGDEV 117 Query: 158 TIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIF 217 I P + +Y + + T T + Q V P A+TP+T ++ Sbjct: 118 IIPA--PFWVSYPEMVKLAEGTPVILPTTVETQFKV----SPEQI---RQAITPKTKLLV 168 Query: 218 FCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFI-EDGSPRSI-YEIPGAREV 275 F +P+NPTG V + ++ + A G ++ D Y + +D SI P A E Sbjct: 169 FNTPSNPTGMVYTPDEVRAIAQVAVEAGLWVLSDEIYEKILYDDAQHLSIGAASPEAYER 228 Query: 276 AIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLA 335 ++ S F+K TG R+G+ P P++ +I S + AQ G +A Sbjct: 229 SVVCSGFAKTYAMTGWRVGFLAGP--------VPLVKAATKIQGHSTSNVCTFAQYGAIA 280 Query: 336 CL--SSGGLKEIRSVNNYYKENRKILMDTLVSL-GLKVYGGVNAPYLW--VHFKGSKSWD 390 S ++E+ + + E R+ ++D L ++ GL+ A Y++ + G S D Sbjct: 281 AYENSQDCVQEMLAA---FAERRRYMLDALNAMPGLECPKPDGAFYMFPSIAKTGRSSLD 337 Query: 391 VFNEILENTHIITVPGSGFGPGGEEYLRISGFGRRDHIVEASKRLQNFFN 440 +E+L+ + TVPG+ F G ++ +R+S D I +RL+ F + Sbjct: 338 FCSELLDQHQVATVPGAAF--GADDCIRLSYATDLDTIKRGMERLEKFLH 385 >1GC4-A nrPDB Length = 385 Score = 84.7 bits (208), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 99/397 (24%), Positives = 159/397 (40%), Gaps = 46/397 (11%) Query: 56 INRRELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNK 115 +N + LE + V L++L G+ PE + A + +G Y G Sbjct: 19 VNAKALEL--RRQGVDLVALTAGEPDFDTPEHVKE-----AARRALAQGKTKYAPPAGIP 71 Query: 116 TLRKAIAETFYRD--LHVKSNEVFVS-DGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDS 172 LR+A+AE F R+ L V E V+ G+Q+ + Q +L + V P + +Y + Sbjct: 72 ELREALAEKFRRENGLSVTPEETIVTVGGSQALFNLFQAILDPGDEVIVLSPYWVSYPEM 131 Query: 173 SVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPD-----LAMTPRTDVIFFCSPNNPTGY 227 G VV + P F PD A+TPRT + SPNNPTG Sbjct: 132 VRFAGGV------------VVEVETLPEEGFVPDPERVRRAITPRTKALVVNSPNNPTGA 179 Query: 228 VASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPG--AREVAIEVSSFSKF 285 V ++ L L A + ++ D Y + +G S PG A E + V+ +K Sbjct: 180 VYPKEVLEALARLAVEHDFYLVSDEIYEHLLYEGEHFS----PGRVAPEHTLTVNGAAKA 235 Query: 286 AGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKE- 344 TG R+G++ P E +I + S IAQ L L++ Sbjct: 236 FAMTGWRIGYACGPKE--------VIKAMASVSRQSTTSPDTIAQWATLEALTNQEASRA 287 Query: 345 -IRSVNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSWDV-FNEILENTHII 402 + Y+ R +L++ L +LGLK A Y+ + +V E L + Sbjct: 288 FVEMAREAYRRRRDLLLEGLTALGLKAVRPSGAFYVLMDTSPIAPDEVRAAERLLEAGVA 347 Query: 403 TVPGSGFGPGGEEYLRISGFGRRDHIVEASKRLQNFF 439 VPG+ F G ++R+S +++ +A +R Sbjct: 348 VVPGTDFAAFG--HVRLSYATSEENLRKALERFARVL 382 >2O1B-A nrPDB Length = 404 Score = 81.6 bits (200), Expect = 6e-16, Method: Compositional matrix adjust. Identities = 87/376 (23%), Positives = 155/376 (41%), Gaps = 28/376 (7%) Query: 66 KHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETF 125 +H + LI++ G P P+ I H F L+ E + YG G + ++AI + + Sbjct: 43 EHGPLPLINMAVGIPDGPTPQGIIDH---FQKALTIPENQK-YGAFHGKEAFKQAIVDFY 98 Query: 126 YRDLHV---KSNEVFVSDGAQSDISRL-QLLLGSNVTIAVQDPTFPAYIDSSVII-GQTG 180 R +V K +EV + G ++ + + ++ + + DP + Y+ ++ G+ Sbjct: 99 QRQYNVTLDKEDEVCILYGTKNGLVAVPTCVINPGDYVLLPDPGYTDYLAGVLLADGKPV 158 Query: 181 HFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDF 240 + + Y P+ S D + +T +I+ PNNPTG A+++ + + Sbjct: 159 PLNLEPPHYL--------PDWSKV-DSQIIDKTKLIYLTYPNNPTGSTATKEVFDEAIAK 209 Query: 241 AKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPD 300 K + I+ D AY AF D SI ++VAIE+ S SK +G R+G+++ Sbjct: 210 FKGTDTKIVHDFAYGAFGFDAKNPSILASENGKDVAIEIYSLSKGYNMSGFRVGFAVGNK 269 Query: 301 ELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILM 360 ++ I + T + G Q + L+ + +N +K R Sbjct: 270 DM--------IQALKKYQTHTNAGMFGALQDAAIYALNHYD-DFLEEQSNVFKTRRDRFE 320 Query: 361 DTLVSLGLKVYGGVNAPYLWVHFKGSKSWDVFNEIL-ENTHIITVPGSGFGPGGEEYLRI 419 L L Y+W+ + F + L + I+ PG FG G Y+RI Sbjct: 321 AMLAKADLPFVHAKGGIYVWLETPPGYDSEQFEQFLVQEKSILVAPGKPFGENGNRYVRI 380 Query: 420 SGFGRRDHIVEASKRL 435 S + EA+ RL Sbjct: 381 SLALDDQKLDEAAIRL 396 >5WMH-A nrPDB Length = 475 Score = 80.9 bits (198), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 87/360 (24%), Positives = 156/360 (43%), Gaps = 47/360 (13%) Query: 103 EGYRGYGLEQGNKTLRKAIAETFYRD--LHVKSNEVFVSDGAQSDISRLQLLLGS-NVTI 159 EG+ Y L G LR+AI + L +++ VS+GA+ + + L + S + Sbjct: 127 EGFTRYTLNAGITELREAICRKLKEENGLSYAPDQILVSNGAKQSLLQAVLAVCSPGDEV 186 Query: 160 AVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPD-----LAMTPRTD 214 + P + +Y + + + T V +P +N+F D +T ++ Sbjct: 187 IIPAPYWVSYTEQARLADATP------------VVIPTKISNNFLLDPKDLESKLTEKSR 234 Query: 215 VIFFCSPNNPTGYVASRKQLHQLVD-FAKTNGSIIIFDSAYAAFI-EDGSPRSIYEIPGA 272 ++ CSP+NPTG V + L ++ AK +++ D Y I + S +P Sbjct: 235 LLILCSPSNPTGSVYPKSLLEEIARIIAKHPRLLVLSDEIYEHIIYAPATHTSFASLPDM 294 Query: 273 REVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAG 332 E + V+ FSK TG RLG+ P I+ ++ +GAS+IAQ Sbjct: 295 YERTLTVNGFSKAFAMTGWRLGYLAGPKH--------IVAACSKLQGQVSSGASSIAQKA 346 Query: 333 GLACLSSG--GLKEIRSVNNYYKENRKILMDTLVSL-GLKVYGGVNAPYLWVHFKG---- 385 G+A L G G + + + Y+E R L+ +L + G+K+ A YL++ F Sbjct: 347 GVAALGLGKAGGETVAEMVKAYRERRDFLVKSLGDIKGVKISEPQGAFYLFIDFSAYYGS 406 Query: 386 -SKSWDVFNE-------ILENTHIITVPGSGFGPGGEEYLRISGFGRRDHIVEASKRLQN 437 ++ + + N+ L+ + VPG F G + +RIS D + A ++++ Sbjct: 407 EAEGFGLINDSSSLALYFLDKFQVAMVPGDAF--GDDSCIRISYATSLDVLQAAVEKIRK 464 >4MY5-A nrPDB Length = 393 Score = 77.4 bits (189), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 99/409 (24%), Positives = 159/409 (38%), Gaps = 38/409 (9%) Query: 41 NVNLEKLKNNYLFPEINRRELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLS 100 N NL K++ + + R+ + I P+V ++LG D P H+ A Sbjct: 10 NKNLNKIEVSMI-----RQFDQSISDIPDVLKLTLGEPDFATP------KHIKEAAKRAI 58 Query: 101 TVEGYRGYGLEQGNKTLRKAIAETFYRDLHVK---SNEVFVSDGAQSDIS-RLQLLLGSN 156 + G+ G LR+A + H+ NE+ V+ GA +S L +L Sbjct: 59 DADESHYTGM-AGLLALRQAASAFVKEKYHLTYNPDNEILVTIGATEALSASLTAILEPG 117 Query: 157 VTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVI 216 + + P +P Y ++G E + + V P + + + Sbjct: 118 DKVLLPAPAYPGYEPVVNLVG--AEVVEIDTRSNDFVLTPEMLEEAILKE---GEALKAV 172 Query: 217 FFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDG-SPRSIYE-IPGARE 274 P NPTG SR+Q+ L + K +I D YA G S SI E +P + Sbjct: 173 ILNYPTNPTGVTYSRQQIKNLAEVLKKYPIFVISDEVYAELTYTGESHVSIAEYLP---D 229 Query: 275 VAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGL 334 I +S SK TG RLG P L +I +VT A+ Q + Sbjct: 230 QTILISGLSKSHAMTGWRLGLIFAPAVLTAQ----LIKSHQYLVT----AATTSVQFAAI 281 Query: 335 ACLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHF---KGSKSWDV 391 L++G + Y K R +++ + ++ K+ A Y++ +G S+ Sbjct: 282 EALTNGKDDALPMKEEYIK-RRDYIIEKMEAMKFKIIKPDGAFYIFAKIPVAQGQDSFKF 340 Query: 392 FNEILENTHIITVPGSGFGPGGEEYLRISGFGRRDHIVEASKRLQNFFN 440 + + + +PG FG GE YLRIS + I EA KRL+ F Sbjct: 341 LQDFAKEKAVAFIPGVAFGKYGEGYLRISYAASMETIKEAMKRLKEFME 389 >1XI9-A nrPDB Length = 406 Score = 75.5 bits (184), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 106/409 (25%), Positives = 168/409 (41%), Gaps = 55/409 (13%) Query: 59 RELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLR 118 RELE +++I L GD + Q HM A+ + EG+ YG +G LR Sbjct: 31 RELEK----KGIKVIRLNIGDPVK-FDFQPPEHMKE-AYCKAIKEGHNYYGDSEGLPELR 84 Query: 119 KAIAETFYRD--LHVKSNEVFVSDGAQSDISRLQLLLGSNV----TIAVQDPTFPAYIDS 172 KAI E R + + ++V V+ LQL+ G+ + I V P++P Y Sbjct: 85 KAIVEREKRKNGVDITPDDVRVTAAVTE---ALQLIFGALLDPGDEILVPGPSYPPYT-- 139 Query: 173 SVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDL-----AMTPRTDVIFFCSPNNPTGY 227 G + K +Y+ + + PD+ +T RT I +PNNPTG Sbjct: 140 ----GLVKFYGGKPVEYRTI------EEEDWQPDIDDIRKKITDRTKAIAVINPNNPTGA 189 Query: 228 VASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDG---SPRSI-YEIPGAREVAIEVSSFS 283 + +K L ++++ A +I D Y +G SP S+ ++P I ++ S Sbjct: 190 LYDKKTLEEILNIAGEYEIPVISDEIYDLMTYEGEHISPGSLTKDVP-----VIVMNGLS 244 Query: 284 KFAGFTGVRLGWSIIPD-ELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGL 342 K TG RLG+ D E S I+ RI N + A GL +G + Sbjct: 245 KVYFATGWRLGYMYFVDPENKLSEVREAIDRLARIRLCP-NTPAQFAAIAGL----TGPM 299 Query: 343 KEIRSVNNYYKENRKILMDTLVSL-GLKVYGGVNAPYLWVH-----FKGSKSWDVFNEIL 396 ++ KE R + L + G+ A Y++ +K K + + ++L Sbjct: 300 DYLKEYMKKLKERRDYIYKRLNEIPGISTTKPQGAFYIFPKIEVGPWKNDKEFVL--DVL 357 Query: 397 ENTHIITVPGSGFGPGGEEYLRISGFGRRDHIVEASKRLQNFFNTRTKH 445 N H++ V GSGFG G + R + + EA R + F R K Sbjct: 358 HNAHVLFVHGSGFGEYGAGHFRAVFLPPIEILEEAMDRFEKFMKERLKE 406 >6F35-A nrPDB Length = 410 Score = 70.1 bits (170), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 94/389 (24%), Positives = 158/389 (40%), Gaps = 54/389 (13%) Query: 72 LISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYRD--L 129 +I LG G+ PE + S+ H G Y G L+KAI E F R+ L Sbjct: 43 VIILGAGEPDFDTPEHVKQAASDAIH-----RGETKYTALDGTPELKKAIREKFQRENGL 97 Query: 130 HVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKY 189 + +E+ V+ GA+ Q+L N +A DP I + + H K Sbjct: 98 AYELDEITVATGAK------QILF--NAMMASLDPGDEVIIPTPYWTSYSDIVHICEGK- 148 Query: 190 QNVVYMPCGPNNSFFP-----DLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTN 244 V + C ++ F + A+TPRT + SP+NP+G S L++ + Sbjct: 149 --PVLIACDASSGFRLTAEKLEAAITPRTRWVLLNSPSNPSGAAYSAADYRPLLEVLLRH 206 Query: 245 GSI-IIFDSAYAAFIEDG----SPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIP 299 + ++ D Y + DG +P + PG + + V+ SK TG R+G++ P Sbjct: 207 PHVWLLVDDMYEHIVYDGFRFVTPAQLE--PGLKNRTLTVNGVSKAYAMTGWRIGYAGGP 264 Query: 300 DELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKIL 359 EL I + + + + S+I+QA + L +G ++ ++ R ++ Sbjct: 265 REL--------IKAMAVVQSQATSCPSSISQAASVVAL-NGPQDFLKERTESFQRRRDLV 315 Query: 360 MDTLVSL-GLKVYGGVNAPYLWVHFKG------------SKSWDVFNEILENTHIITVPG 406 ++ L ++ GL A Y + G D +LE+ H+ VPG Sbjct: 316 VNGLNAIDGLDCRVPEGAFYTFSGCAGVLGKVTPSGKRIKTDTDFCAYLLEDAHVAVVPG 375 Query: 407 SGFGPGGEEYLRISGFGRRDHIVEASKRL 435 S FG + RIS + EA +R+ Sbjct: 376 SAFGL--SPFFRISYATSEAELKEALERI 402 >4CVQ-A nrPDB Length = 431 Score = 69.7 bits (169), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 56/214 (26%), Positives = 98/214 (45%), Gaps = 26/214 (12%) Query: 106 RGYGLEQGNKTLRKAIAETF----YRDLHVKSNEVFVSDGAQSDISR-LQLLLGSNVTIA 160 +GY +G + RKAI + + RD+ V+ ++++ +G I + +Q LL S + Sbjct: 92 QGYCDSKGLYSARKAIMQHYQARGMRDVTVE--DIYIGNGVSELIVQAMQALLNSGDEML 149 Query: 161 VQDPTFPAYIDS-SVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDL-----AMTPRTD 214 V P +P + + S+ G+ H+ C ++ +FPDL +TPRT Sbjct: 150 VPAPDYPLWTAAVSLSSGKAVHYL-------------CDESSDWFPDLDDIRAKITPRTR 196 Query: 215 VIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGARE 274 I +PNNPTG V S++ L ++V+ A+ + II D Y + D + Sbjct: 197 GIVIINPNNPTGAVYSKELLMEIVEIARQHNLIIFADEIYDKILYDDAEHHSIAPLAPDL 256 Query: 275 VAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGF 308 + I + SK G R GW ++ ++ G+ Sbjct: 257 LTITFNGLSKTYRVAGFRQGWMVLNGPKKHAKGY 290 >3H14-A nrPDB Length = 391 Score = 69.3 bits (168), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 81/345 (23%), Positives = 134/345 (38%), Gaps = 34/345 (9%) Query: 107 GYGLEQGNKTLRKAIAETF--YRDLHVKSNEVFVSDGAQSD-ISRLQLLLGSNVTIAVQD 163 GY + G LR+ IA + + + + V ++ G+ + L S + + Sbjct: 63 GYTVALGLPALRQRIARLYGEWYGVDLDPGRVVITPGSSGGFLLAFTALFDSGDRVGIGA 122 Query: 164 PTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDV--IFFCSP 221 P +P+Y +G V +P P N P A D+ + SP Sbjct: 123 PGYPSYRQILRALGLV------------PVDLPTAPENRLQPVPADFAGLDLAGLMVASP 170 Query: 222 NNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSS 281 NPTG + + L++ A+ G+ I D Y + + E+ V ++S Sbjct: 171 ANPTGTMLDHAAMGALIEAAQAQGASFISDEIYHGIEYEAKAVTALELTDECYV---INS 227 Query: 282 FSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGG 341 FSK+ TG R+GW ++P++ + RI F A + +Q A + Sbjct: 228 FSKYFSMTGWRVGWMVVPEDQ--------VRVVERIAQNMFICAPHASQV--AALAALDC 277 Query: 342 LKEIRSVNNYYKENRKILMDTLVSLGL-KVYGGVNAPYLWVHFKG--SKSWDVFNEILEN 398 E+++ + YK NRK++++ L G ++ A Y++ S EILE Sbjct: 278 DAELQANLDVYKANRKLMLERLPKAGFTRIAPPDGAFYVYADVSDLTDDSRAFAAEILEK 337 Query: 399 THIITVPGSGFGPG-GEEYLRISGFGRRDHIVEASKRLQNFFNTR 442 + PG F P G LR S I E RL+ F R Sbjct: 338 AGVAVTPGLDFDPERGAGTLRFSYARATADIEEGLDRLEAFMQAR 382 >3ELE-A nrPDB Length = 398 Score = 66.6 bits (161), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 90/390 (23%), Positives = 147/390 (37%), Gaps = 57/390 (14%) Query: 78 GDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETF--YRDLHVKSNE 135 G+ + P P+ + + +V GY QG+ R AIAE H ++ Sbjct: 43 GNPSIPAPQIVNDTIKELVTDYDSV-ALHGYTSAQGDVETRAAIAEFLNNTHGTHFNADN 101 Query: 136 VFVSDGAQSDISRLQLLLGSN-----VTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQ 190 ++++ GA + +S L S+ +TIA P FP Y V + G Sbjct: 102 LYMTMGAAASLSICFRALTSDAYDEFITIA---PYFPEY---KVFVNAAG---------A 146 Query: 191 NVVYMPCGPNNSFFPDLAMTPRTDV----IFFCSPNNPTGYVASRKQLHQLVDFAKTNGS 246 +V +P + A+ R + + SPNNP+G V S + + +L D + Sbjct: 147 RLVEVPADTEHFQIDFDALEERINAHTRGVIINSPNNPSGTVYSEETIKKLSDLLEKKSK 206 Query: 247 ------IIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPD 300 II D Y + DG + + + S+SK G R+G+ ++PD Sbjct: 207 EIGRPIFIIADEPYREIVYDGIKVPF--VTKYYDNTLVCYSYSKSLSLPGERIGYVLVPD 264 Query: 301 ELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVN------NYYKE 354 E+ Y + +A G C S K I N YKE Sbjct: 265 EV-YDKA------------ELYAAVCGAGRALGYVCAPSLFQKMIVKCQGATGDINAYKE 311 Query: 355 NRKILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSWDVFNEILENTHIITVPGSGFGPGGE 414 NR +L + L +G + A Y++V S + F E + ++ V GFG G Sbjct: 312 NRDLLYEGLTRIGYHCFKPDGAFYMFVKALEDDS-NAFCEKAKEEDVLIVAADGFGCPG- 369 Query: 415 EYLRISGFGRRDHIVEASKRLQNFFNTRTK 444 ++RIS R+ I + + + K Sbjct: 370 -WVRISYCVDREMIKHSMPAFEKIYKKYNK 398 >6F77-B nrPDB Length = 400 Score = 62.8 bits (151), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 92/396 (23%), Positives = 152/396 (38%), Gaps = 62/396 (15%) Query: 72 LISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYRD--- 128 +I LG G+ P+ I + + G Y G LR+AIA+ F R+ Sbjct: 33 VIGLGAGEPDFDTPDNIKKAAID-----AIDRGETKYTPVSGIPELREAIAKKFKRENNL 87 Query: 129 LHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKK 188 + + + + G Q + L + + P + +Y + + G T Sbjct: 88 DYTAAQTIVGTGGKQILFNAFMATLNPGDEVVIPAPYWVSYPEMVALCGGT--------- 138 Query: 189 YQNVVYMPCGPNNSFFP-----DLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKT 243 V++P N+F D A+TP+T F SP+NP+G S ++L L D Sbjct: 139 ---PVFVPTRQENNFKLKAEDLDRAITPKTKWFVFNSPSNPSGAAYSHEELKALTDVLMK 195 Query: 244 NGSIIIFDSAYAAFIEDGSPRSIYEI---PGAREVAIEVSSFSKFAGFTGVRLGWSIIPD 300 + + + + G R + PG E + ++ SK TG R+G++ P Sbjct: 196 HPHVWVLTDDMYEHLTYGDFRFATPVEVEPGLYERTLTMNGVSKAYAMTGWRIGYAAGPL 255 Query: 301 ELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILM 360 L I I +GA++IAQ + L+ G ++ N + R+ Sbjct: 256 HL--------IKAMDMIQGQQTSGAASIAQWAAVEALN--GPQDFIGRNKEIFQGRR--- 302 Query: 361 DTLVSLGLKVYGGVNAP------YLWVHFKG------------SKSWDVFNEILENTHII 402 D +VS+ L G++ P Y++ G D +E+LE + Sbjct: 303 DLVVSM-LNQAKGISCPTPEGAFYVYPSCAGLIGKTAPSGKVIETDEDFVSELLETEGVA 361 Query: 403 TVPGSGFGPGGEEYLRISGFGRRDHIVEASKRLQNF 438 V GS FG G RIS + EA +R+Q F Sbjct: 362 VVHGSAFGLGPN--FRISYATSEALLEEACRRIQRF 395 >3EZS-A nrPDB Length = 376 Score = 62.4 bits (150), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 90/372 (24%), Positives = 145/372 (38%), Gaps = 52/372 (13%) Query: 65 EKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAET 124 E P + + LG G+ P+ I + N H L+ Y ++LR A Sbjct: 18 EITPKKRGLDLGIGEPQFETPKFIQDALKNHTHSLNI------YPKSAFEESLRAAQRGF 71 Query: 125 FYR--DLHVKSNEVFVSDGAQS---DISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQT 179 F R + +K NE+ + G++ + L N TIA +P + Y ++ I Sbjct: 72 FKRRFKIELKENELISTLGSREVLFNFPSFVLFDYQNPTIAYPNPFYQIYEGAAKFIKAK 131 Query: 180 GHFHEKTKKYQNVVYMPCGPNNSFFPDL--AMTPRTDVIFFCSPNNPTGYVASRKQLHQL 237 + MP N F P L D++ SPNNPTG S ++L Sbjct: 132 S------------LLMPLTKENDFTPSLNEKELQEVDLVILNSPNNPTGRTLSLEELISW 179 Query: 238 VDFAKTNGSIIIFDSAYAAFIEDGSPRSIYE---IPG--AREVAIEVSSFSKFAGFTGVR 292 V A + I+I D Y+ E+ P S+ E + G A + + + S SK + G+R Sbjct: 180 VKLALKHDFILINDECYSEIYENTPPPSLLEACMLAGNEAFKNVLVIHSLSKRSSAPGLR 239 Query: 293 LGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSV-NNY 351 G+ LL F + + A+ I +A A L + R++ N Sbjct: 240 SGFIAGDSRLLEK-----YKAFRAYL--GYTSANAIQKASEAAWLDDRHAEFFRNIYANN 292 Query: 352 YKENRKILMDTLVSLGLKVYGGVNAPY-LWVHFKGSKSWDVFNEILENTHIITVPGSGFG 410 K RKI +TL+ PY +V+ + + +N IIT+P G Sbjct: 293 LKLARKIFKNTLIY-----------PYSFYVYLPVQNGENFAKTLYQNEGIITLPALYLG 341 Query: 411 PG--GEEYLRIS 420 G +Y+R++ Sbjct: 342 RNRIGADYVRLA 353 >1U08-A nrPDB Length = 386 Score = 62.0 bits (149), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 77/364 (21%), Positives = 150/364 (41%), Gaps = 47/364 (12%) Query: 94 NFAHGLSTVEGYRGYGLEQGNKTLRKAIA---ETFYRDLHVKSNEVFVSDGAQSDI-SRL 149 AH ++ +G Y G + LR+AIA E Y +++ V+ GA + + + Sbjct: 51 RLAHHVA--QGANQYAPMTGVQALREAIAQKTERLYGYQPDADSDITVTAGATEALYAAI 108 Query: 150 QLLLGSNVTIAVQDPTFPAYIDSSVIIG--------QTGHFHEKTKKYQNVVYMPCGPNN 201 L+ + + DP++ +Y + + G Q HF +++ + Sbjct: 109 TALVRNGDEVICFDPSYDSYAPAIALSGGIVKRMALQPPHFRVDWQEFAAL--------- 159 Query: 202 SFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAA--FIE 259 ++ RT ++ +P+NP+ V + L + +I D Y F + Sbjct: 160 -------LSERTRLVILNTPHNPSATVWQQADFAALWQAIAGHEIFVISDEVYEHINFSQ 212 Query: 260 DGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVT 319 G S+ P RE A+ VSSF K TG ++G+ + P + I H+ +T Sbjct: 213 QGH-ASVLAHPQLRERAVAVSSFGKTYHMTGWKVGYCVAPAPISAE-----IRKVHQYLT 266 Query: 320 TSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLKVYGGVNAPYL 379 S N + +A LA + + ++ ++Y++ R IL++ L L++ +L Sbjct: 267 FSVNTPAQLA----LADMLRAEPEHYLALPDFYRQKRDILVNALNESRLEILPCEGTYFL 322 Query: 380 WVHFKGSKSWD--VFNEILENTH-IITVPGSGF--GPGGEEYLRISGFGRRDHIVEASKR 434 V + + D F + L H + +P S F P + +R+ + ++ A++R Sbjct: 323 LVDYSAVSTLDDVEFCQWLTQEHGVAAIPLSVFCADPFPHKLIRLCFAKKESTLLAAAER 382 Query: 435 LQNF 438 L+ Sbjct: 383 LRQL 386 >4WP0-A nrPDB Length = 472 Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 62/264 (23%), Positives = 108/264 (40%), Gaps = 16/264 (6%) Query: 55 EINRRELEHIEKHPNVQ---------LISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGY 105 ++ R L+ I+ +P V+ +++LG G P P+ + G + Y Sbjct: 4 QLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQY 63 Query: 106 -RGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQDP 164 + +G K L E +++ N + G + + Q L+ + + +P Sbjct: 64 TKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEP 123 Query: 165 TFPAYIDSSVIIGQTGHFHE-KTKKYQNVVYMPCGPNNSFFP-DLA--MTPRTDVIFFCS 220 F Y +++ G F K QN + N P +LA T RT + + Sbjct: 124 FFDCYEPMTMMAGGRPVFVSLKPGPIQNG-ELGSSSNWQLDPMELAGKFTSRTKALVLNT 182 Query: 221 PNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPR-SIYEIPGAREVAIEV 279 PNNP G V SR++L + + + + I D Y + DG SI +PG E + + Sbjct: 183 PNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTI 242 Query: 280 SSFSKFAGFTGVRLGWSIIPDELL 303 S K TG ++GW + PD ++ Sbjct: 243 GSAGKTFSATGWKVGWVLGPDHIM 266 >3OP7-A nrPDB Length = 375 Score = 60.5 bits (145), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 78/348 (22%), Positives = 145/348 (41%), Gaps = 42/348 (12%) Query: 108 YGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQ-SDISRLQLLLGSNVTIAVQDPTF 166 YG +G+ +K++++ + VK ++ ++GA +++ L L+ + PT+ Sbjct: 59 YGWIEGSPAFKKSVSQLY---TGVKPEQILQTNGATGANLLVLYSLIEPGDHVISLYPTY 115 Query: 167 PAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLA-----MTPRTDVIFFCSP 221 D +G + ++ N + PDL + P T +I + Sbjct: 116 QQLYDIPKSLGAEVDLWQIEEE------------NGWLPDLEKLRQLIRPTTKMICINNA 163 Query: 222 NNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSS 281 NNPTG V R L +LV+ A G+ I+ D Y +F E P SI E+ + I V+S Sbjct: 164 NNPTGAVMDRTYLEELVEIASEVGAYILSDEVYRSFSELDVP-SIIEV---YDKGIAVNS 219 Query: 282 FSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGG 341 SK G+R+GW ++ ++ D+ I F+ +A L+ Sbjct: 220 LSKTYSLPGIRIGWVAANHQV--TDILRDYRDYTMICAGVFDDL--------VAQLALAH 269 Query: 342 LKEIRSVNNY-YKENRKILMDTLVSLGLKVY---GGVNAPYLWVHFKGSKSWDVFNEILE 397 +EI N + +EN IL + L Y V+ ++ + D ++L+ Sbjct: 270 YQEILERNRHILEENLAILDQWIEEEPLVSYIRPAVVSTSFVKIAVDMPME-DFCLQLLQ 328 Query: 398 NTHIITVPGSGFGPGGEEYLRISGFGRRDHIVEASKRLQNFFNTRTKH 445 ++ VPG+ F G Y+R+ ++ +++ ++L F K Sbjct: 329 EHGVLLVPGNRFERDG--YVRLGFACEQETLIKGLEKLSQFLRRFDKE 374 >3FVS-A nrPDB Length = 422 Score = 60.1 bits (144), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 62/264 (23%), Positives = 108/264 (40%), Gaps = 16/264 (6%) Query: 55 EINRRELEHIEKHPNVQ---------LISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGY 105 ++ R L+ I+ +P V+ +++LG G P P+ + G + Y Sbjct: 4 QLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQY 63 Query: 106 -RGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQDP 164 + +G K L E +++ N + G + + Q L+ + + +P Sbjct: 64 TKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEP 123 Query: 165 TFPAYIDSSVIIGQTGHFHE-KTKKYQNVVYMPCGPNNSFFP-DLA--MTPRTDVIFFCS 220 F Y +++ G F K QN + N P +LA T RT + + Sbjct: 124 FFDCYEPMTMMAGGRPVFVSLKPGPIQNG-ELGSSSNWQLDPMELAGKFTSRTKALVLNT 182 Query: 221 PNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPR-SIYEIPGAREVAIEV 279 PNNP G V SR++L + + + + I D Y + DG SI +PG E + + Sbjct: 183 PNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTI 242 Query: 280 SSFSKFAGFTGVRLGWSIIPDELL 303 S K TG ++GW + PD ++ Sbjct: 243 GSAGKTFSATGWKVGWVLGPDHIM 266 >3JTX-A nrPDB Length = 396 Score = 59.7 bits (143), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 73/283 (25%), Positives = 119/283 (42%), Gaps = 41/283 (14%) Query: 41 NVNLEKLKNNYLFPEINRRELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLS 100 N L++LK Y F ++ ++ I ++ + L G+ P P+ IT ++ H L Sbjct: 3 NTLLKQLKP-YPFARLHE-AMQGISAPEGMEAVPLHIGEPKHPTPKVITDALTASLHELE 60 Query: 101 TVEGYRGYGLEQGNKTLRKAIAETF---YRDLHVKS-NEVFVSDGAQSDI-SRLQLLL-- 153 Y L G LR+A A Y L V + NE+ G++ + S +Q +L Sbjct: 61 K------YPLTAGLPELRQACANWLKRRYDGLTVDADNEILPVLGSREALFSFVQTVLNP 114 Query: 154 ---GSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDL--- 207 G I +P + Y ++++ G HF C P SF PD Sbjct: 115 VSDGIKPAIVSPNPFYQIYEGATLLGGGEIHFAN------------C-PAPSFNPDWRSI 161 Query: 208 --AMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSP-- 263 + RT ++F CSPNNP+G V ++ D G II D Y+ DG+ Sbjct: 162 SEEVWKRTKLVFVCSPNNPSGSVLDLDGWKEVFDLQDKYGFIIASDECYSEIYFDGNKPL 221 Query: 264 ---RSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELL 303 ++ ++ +R+ + +S SK + G+R G+ ELL Sbjct: 222 GCLQAAAQLGRSRQKLLMFTSLSKRSNVPGLRSGFVAGDAELL 264 >4M2J-A nrPDB Length = 406 Score = 58.5 bits (140), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 52/206 (25%), Positives = 91/206 (44%), Gaps = 22/206 (10%) Query: 110 LEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDIS-RLQLLLGSNVTIAVQDPTFPA 168 + QG + +R+AIA+ + ++ V V+ G+ I+ L LL + VQ+ + + Sbjct: 82 VSQGGEGVRRAIADRYAGG---DADRVLVTHGSSEAIALTLNALLHRGDRVVVQEGIYHS 138 Query: 169 YIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLA---MTPRTDVIFFCSPNNPT 225 GH+ V+ + PD+ +TP T + P+NPT Sbjct: 139 L----------GHYPRAAGCDVAVLPGRAVRDGEIDPDVLAGLVTPGTAAVIVNFPHNPT 188 Query: 226 GYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAR-EVAIEVSSFSK 284 G S + L L + G+++++D+A A E + PGA + + SK Sbjct: 189 GVTLSPQGLRALKERTAATGAVLVWDAATA---EIAHRWEVLADPGADGGDTVSYGTLSK 245 Query: 285 FAGFTGVRLGWSIIPDELLYSNGFPI 310 G G+R+GW++ P ELL + FP+ Sbjct: 246 TFGLPGLRVGWAVAPKELLTAT-FPL 270 >1LC8-A nrPDB Length = 364 Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 32/96 (33%), Positives = 48/96 (50%), Gaps = 6/96 (6%) Query: 208 AMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIY 267 A+TP D +F C+PNNPTG + R L + D K+ +I D A+ FI P Sbjct: 142 ALTPDLDCLFLCTPNNPTGLLPERPLLQAIADRCKSLNINLILDEAFIDFI----PHETG 197 Query: 268 EIPGAREVA--IEVSSFSKFAGFTGVRLGWSIIPDE 301 IP ++ + S +KF G+RLG+ + D+ Sbjct: 198 FIPALKDNPHIWVLRSLTKFYAIPGLRLGYLVNSDD 233 >2DOU-A nrPDB Length = 376 Score = 56.2 bits (134), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 59/249 (23%), Positives = 101/249 (40%), Gaps = 19/249 (7%) Query: 60 ELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRK 119 E + + V LI L G T P PE + + A L+ Y GY L+ + Sbjct: 15 EAKRKARERGVGLIDLSIGSTDLPPPE---APLKALAEALNDPTTY-GYCLKSCTLPFLE 70 Query: 120 AIAETFYRDLHV---KSNEVFVSDGAQSDISRLQLLLGS-NVTIAVQDPTFPAYIDSSVI 175 A + V E G+Q ++ L L L + + + +P+Y ++ + Sbjct: 71 EAARWYEGRYGVGLDPRREALALIGSQEGLAHLLLALTEPEDLLLLPEVAYPSYFGAARV 130 Query: 176 IG-QTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQL 234 +T + ++ +P G + V+ PNNPTG VA Sbjct: 131 ASLRTFLIPLREDGLADLKAVPEG----------VWREAKVLLLNYPNNPTGAVADWGYF 180 Query: 235 HQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLG 294 + + A+ +G +I D+ Y + +G S +PGA+E +E+ S SK G RLG Sbjct: 181 EEALGLARKHGLWLIHDNPYVDQVYEGEAPSPLALPGAKERVVELFSLSKSYNLAGFRLG 240 Query: 295 WSIIPDELL 303 +++ +E L Sbjct: 241 FALGSEEAL 249 >2ZJG-A nrPDB Length = 410 Score = 55.8 bits (133), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 58/250 (23%), Positives = 104/250 (41%), Gaps = 11/250 (4%) Query: 60 ELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRK 119 E + P+V ++LG G P + +S A + + RG+G K L Sbjct: 15 EFTKLAADPSV--VNLGQGFPDISPPSYVKEELSKAAFIDNMNQYTRGFGHPALVKALSC 72 Query: 120 AIAETFYRDLHVKSNEVFVSDGAQSDI-SRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQ 178 + + R + + E+ V+ GA + + +Q L+ + + P + Y + G Sbjct: 73 LYGKIYQRQID-PNEEILVAVGAYGSLFNSIQGLVDPGDEVIIMVPFYDCYEPMVRMAGA 131 Query: 179 TGHFHE-KTKKYQNVVYMPCGPNNSFFP---DLAMTPRTDVIFFCSPNNPTGYVASRKQL 234 F ++K + + + +F P + + +T I +P+NP G V +R++L Sbjct: 132 VPVFIPLRSKPTDGMKWT--SSDWTFDPRELESKFSSKTKAIILNTPHNPLGKVYTRQEL 189 Query: 235 HQLVDFAKTNGSIIIFDSAYAAFIEDGSPR-SIYEIPGAREVAIEVSSFSKFAGFTGVRL 293 + D + ++ I D Y + G I +PG E I + S K TG +L Sbjct: 190 QVIADLCVKHDTLCISDEVYEWLVYTGHTHVKIATLPGMWERTITIGSAGKTFSVTGWKL 249 Query: 294 GWSIIPDELL 303 GWSI P L+ Sbjct: 250 GWSIGPAHLI 259 >4R2N-A nrPDB Length = 367 Score = 53.1 bits (126), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 32/90 (35%), Positives = 49/90 (54%), Gaps = 3/90 (3%) Query: 209 MTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDG-SPRSIY 267 +T RT +IF C+PNNPT V L + V+ + +I D AY +I DG P S+ Sbjct: 144 VTDRTRLIFVCNPNNPTSTVVGPDALARFVEAVPAH-ILIAIDEAYVEYIRDGMRPDSLG 202 Query: 268 EIPGAREVAIEVSSFSKFAGFTGVRLGWSI 297 + V + + +FSK G G+R+G++I Sbjct: 203 LVRAHNNVVV-LRTFSKAYGLAGLRIGYAI 231 >3FFH-A nrPDB Length = 363 Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 42/189 (22%), Positives = 85/189 (44%), Gaps = 16/189 (8%) Query: 116 TLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRL-QLLLGSNVTIAVQDPTFPAYIDSSV 174 +LRK +A+ FY ++ E+ + G I L ++LL + + PTF Y +++ Sbjct: 71 SLRKEVAD-FY---QLEEEELIFTAGVDELIELLTRVLLDTTTNTVMATPTFVQYRQNAL 126 Query: 175 IIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQL 234 I G + + + + G ++ A+ +T +++ C+PNNPTG + Sbjct: 127 IEGA---------EVREIPLLQDGEHDLEGMLNAIDEKTTIVWICNPNNPTGNYIELADI 177 Query: 235 HQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLG 294 +D ++ +++ D AY ++ P ++ + I +FSK G R+G Sbjct: 178 QAFLDRVPSD-VLVVLDEAYIEYV-TPQPEKHEKLVRTYKNLIITRTFSKIYGLASARVG 235 Query: 295 WSIIPDELL 303 + I E++ Sbjct: 236 YGIADKEII 244 >3DZZ-A nrPDB Length = 391 Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 65/293 (22%), Positives = 117/293 (39%), Gaps = 34/293 (11%) Query: 159 IAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFF 218 I VQ+P + + SVI G Y+N Y N + + TP ++ F Sbjct: 112 ILVQEPVYNMFY--SVIEGNGRRVISSDLIYENSKY---SVNWADLEEKLATPSVRMMVF 166 Query: 219 CSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFI---EDGSPRSIYEIPGAREV 275 C+P+NP GY S +++ ++ + + ++I D + + ED +P + A+ Sbjct: 167 CNPHNPIGYAWSEEEVKRIAELCAKHQVLLISDEIHGDLVLTDEDITPAFTVDW-DAKNW 225 Query: 276 AIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSF----NGASNIAQA 331 + + S SK + +IIP+ D SF G N+ Sbjct: 226 VVSLISPSKTFNLAALHAACAIIPNP-----------DLRARAEESFFLAGIGEPNLLAI 274 Query: 332 GGLACLSSGGLKEIRSVNNYYKEN----RKILMDTLVSLGLKVYGGVNAPYL-WVHFK-- 384 G +R + ++N R+ L + +KV NA YL WV Sbjct: 275 PAAIAAYEEGHDWLRELKQVLRDNFAYAREFLAKEVPE--VKVLDS-NASYLAWVDISAL 331 Query: 385 GSKSWDVFNEILENTHIITVPGSGFGPGGEEYLRISGFGRRDHIVEASKRLQN 437 G + D + E T +I G+G+ G E++RI+ ++ +++ +RL+ Sbjct: 332 GMNAEDFCKYLREKTGLIISAGNGYRGNGHEFVRINLACPKELVIDGMQRLKQ 384 >2O0R-A nrPDB Length = 411 Score = 50.4 bits (119), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 33/99 (33%), Positives = 52/99 (52%), Gaps = 5/99 (5%) Query: 208 AMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGS---PR 264 A+TPRT + SP+NPTG V S +L + + A ++I D Y + D + P Sbjct: 156 AVTPRTRALIINSPHNPTGAVLSATELAAIAEIAVAANLVVITDEVYEHLVFDHARHLPL 215 Query: 265 SIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELL 303 + ++ G E I +SS +K TG ++GW+ P EL+ Sbjct: 216 AGFD--GMAERTITISSAAKMFNCTGWKIGWACGPAELI 252 >3T32-A nrPDB Length = 383 Score = 49.7 bits (117), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 75/315 (23%), Positives = 123/315 (39%), Gaps = 49/315 (15%) Query: 147 SRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPD 206 + +Q N ++ VQ P +P + + T Q V N+++ D Sbjct: 97 TSIQAFTKENESVLVQPPIYPPFFEMVT-----------TNNRQLCVSPLQKQNDTYAID 145 Query: 207 LAMTPR-----TDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFI--- 258 + ++ CSP+NP G V +++L +L I++ D ++ I Sbjct: 146 FEHLEKQFQQGVKLMLLCSPHNPIGRVWKKEELTKLGSLCTKYNVIVVADEIHSDIIYAD 205 Query: 259 EDGSP-RSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELL--------YSNGFP 309 +P S+ E AR I + SK G++ IIP+E L Y GF Sbjct: 206 HTHTPFASLSEELAAR--TITCMAPSKTFNIAGLQASIIIIPNEKLRQAFTSIQYRQGFH 263 Query: 310 IINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILMDTLVSL--G 367 +N F A Q+ C + L EIR Y ++N K + + Sbjct: 264 GLNIF----------AYTAMQSAYTEC--NDWLNEIRF---YIEDNAKFACEYIKDHIPT 308 Query: 368 LKVYGGVNAPYLWVHFKG-SKSWDVFNEILENT-HIITVPGSGFGPGGEEYLRISGFGRR 425 L V + LW+ + S D ++LE II PG +G GGEE++ I+ R Sbjct: 309 LSVMKPEGSFLLWIDCSALNLSQDERTKLLEEKGKIIVEPGEKYGLGGEEHIGINIGCPR 368 Query: 426 DHIVEASKRLQNFFN 440 + E RL++ F+ Sbjct: 369 SVLEEILNRLRHTFS 383 >1YIY-A nrPDB Length = 429 Score = 48.1 bits (113), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 27/93 (29%), Positives = 43/93 (46%), Gaps = 1/93 (1%) Query: 212 RTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFI-EDGSPRSIYEIP 270 +T +I +P+NP G V R +L + + K + + D Y + E I +P Sbjct: 182 KTKMIIINTPHNPLGKVMDRAELEVVANLCKKWNVLCVSDEVYEHMVFEPFEHIRICTLP 241 Query: 271 GAREVAIEVSSFSKFAGFTGVRLGWSIIPDELL 303 G E I + S K TG ++GW+ P+ LL Sbjct: 242 GMWERTITIGSAGKTFSLTGWKIGWAYGPEALL 274 >3B46-A nrPDB Length = 447 Score = 48.1 bits (113), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 47/185 (25%), Positives = 74/185 (40%), Gaps = 29/185 (15%) Query: 130 HVKSNEVFVSDGAQSDI-SRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKK 188 +K+ V V+ GA I S L LL + + V +P F YI + + G Sbjct: 115 ELKAENVTVTTGANEGILSCLMGLLNAGDEVIVFEPFFDQYIPNIELCGG---------- 164 Query: 189 YQNVVYMPCGPNNSFFP---------------DLAMTPRTDVIFFCSPNNPTGYVASRKQ 233 VVY+P P + A+T +T + +P+NP G V +R++ Sbjct: 165 --KVVYVPINPPKELDQRNTRGEEWTIDFEQFEKAITSKTKAVIINTPHNPIGKVFTREE 222 Query: 234 LHQLVDFAKTNGSIIIFDSAYA-AFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVR 292 L L + + +II D Y + D R P ++ + V S K TG R Sbjct: 223 LTTLGNICVKHNVVIISDEVYEHLYFTDSFTRIATLSPEIGQLTLTVGSAGKSFAATGWR 282 Query: 293 LGWSI 297 +GW + Sbjct: 283 IGWVL 287 >4RAE-A nrPDB Length = 394 Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 46/159 (28%), Positives = 68/159 (42%), Gaps = 17/159 (10%) Query: 212 RTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPG 271 + DV+F SPNNP+G S L +L+D A I I D AY F S S+ E Sbjct: 166 KPDVVFIASPNNPSGQSVSLPDLCKLLDVAP---GIAIVDEAYGEFSSQPSAVSLVEEYP 222 Query: 272 AREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQA 331 ++ V + SK F G RLG+ I P + D +V ++ S++ QA Sbjct: 223 SKLVVTR--TMSKAFAFAGGRLGYLI---------ATPAVIDAMLLVRLPYH-LSSVTQA 270 Query: 332 GGLACLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLKV 370 A L + SV E ++ +L +G +V Sbjct: 271 AARAALRHSD-DTLSSVAALIAERERV-TTSLNDMGFRV 307 >6C3C-A nrPDB Length = 413 Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 29/87 (33%), Positives = 45/87 (51%), Gaps = 9/87 (10%) Query: 201 NSFFPDLAMTPRTDVIFFCSPNNPTGYVA---SRKQLHQLVDFAKTNGSIIIFDSAYAAF 257 + +P+L RTD +F PNNPTG+ RK ++V F K + +++ D +A+F Sbjct: 165 DRIYPELERRVRTDALFLVDPNNPTGFSLLRHGRKGFEEVVRFCKDHDKLLLIDFCFASF 224 Query: 258 --IEDGSPR-SIYEI---PGAREVAIE 278 E R +YE+ G R +AIE Sbjct: 225 TLFEPELARFDMYELLENSGVRYLAIE 251 >4DQ6-A nrPDB Length = 391 Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 79/348 (22%), Positives = 138/348 (39%), Gaps = 34/348 (9%) Query: 108 YGLEQGNKTLRKAIAETFYR--DLHVKSNEVFVSDGAQSDISRL-QLLLGSNVTIAVQDP 164 YG + ++I YR + +KS + S G IS L L +N I +Q+P Sbjct: 63 YGYTTRPDSYNESIVNWLYRRHNWKIKSEWLIYSPGVIPAISLLINELTKANDKIMIQEP 122 Query: 165 TFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIF-FCSPNN 223 + + +S V +K +N Y+ + D+ + +F C+P+N Sbjct: 123 VYSPF-NSVVKNNNRELIISPLQKLENGNYI------MDYEDIENKIKDVKLFILCNPHN 175 Query: 224 PTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGA------REVAI 277 P G V ++ +L +L D + II D ++ I + IP A + I Sbjct: 176 PVGRVWTKDELKKLGDICLKHNVKIISDEIHSDII----LKKHKHIPMASISKEFEKNTI 231 Query: 278 EVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIIND-FHRIVTTSFNGASNIAQAGGLAC 336 + +K G++ + ++PDE + +++D F RI N S +A Sbjct: 232 TCMAPTKTFNIAGLQSSYVVLPDE----KDYKLLDDAFTRIDIKRNNCFSLVATEASY-- 285 Query: 337 LSSGGLKEIRSVNNYYKENRKILMDTLVS--LGLKVYGGVNAPYLWVHFK--GSKSWDVF 392 + G + S Y + N + + LKV LWV F G ++ Sbjct: 286 --NNGESWLESFLEYLESNIDFAIKYINENMPKLKVRKPEGTYLLWVDFSALGLSDEELE 343 Query: 393 NEILENTHIITVPGSGFGPGGEEYLRISGFGRRDHIVEASKRLQNFFN 440 + +++ + G+ FG GG Y RI+ R + EA R++N N Sbjct: 344 SILVQKGKVALNQGNSFGIGGSGYQRINLACPRSMLEEALIRIKNAIN 391 >1BW0-A nrPDB Length = 416 Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 59/252 (23%), Positives = 95/252 (37%), Gaps = 34/252 (13%) Query: 107 GYGLEQGNKTLRKAIAETFYRD--LH--------VKSNEVFVSDGAQSDISRLQLLLGSN 156 GY G+ R+A+A T++R+ +H VK N V S G+ + + + + Sbjct: 70 GYFPTVGSPEAREAVA-TWWRNSFVHKEELKSTIVKDNVVLCSGGSHGILMAITAICDAG 128 Query: 157 VTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPR---- 212 V P FP Y G HF+ C P N + DL R Sbjct: 129 DYALVPQPGFPHYETVCKAYGIGMHFYN------------CRPENDWEADLDEIRRLKDD 176 Query: 213 -TDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDG-SPRSIYEIP 270 T ++ +P+NP G SRK + +V A+ + D YA + G P + + Sbjct: 177 KTKLLIVTNPSNPCGSNFSRKHVEDIVRLAEELRLPLFSDEIYAGMVFKGKDPNATFTSV 236 Query: 271 GAREVAIE---VSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASN 327 E + + +K G RLGW + D + NG + R+ + Sbjct: 237 ADFETTVPRVILGGTAKNLVVPGWRLGWLLYVDP--HGNGPSFLEGLKRVGMLVCGPCTV 294 Query: 328 IAQAGGLACLSS 339 + A G A L++ Sbjct: 295 VQAALGEALLNT 306 >3LY1-A nrPDB Length = 354 Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 26/84 (30%), Positives = 44/84 (52%), Gaps = 2/84 (2%) Query: 215 VIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYE-IPGAR 273 +++ +PNNPTG + + + +K ++ I D AYA F+ D RSI I Sbjct: 144 IVYLVNPNNPTGTITPADVIEPWIA-SKPANTMFIVDEAYAEFVNDPRFRSISPMITQGA 202 Query: 274 EVAIEVSSFSKFAGFTGVRLGWSI 297 E I + +FSK G+R+G+++ Sbjct: 203 ENIILLKTFSKIHAMAGMRVGYAV 226 >2HOR-A nrPDB Length = 427 Score = 45.8 bits (107), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 82/377 (21%), Positives = 143/377 (37%), Gaps = 52/377 (13%) Query: 88 ITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDIS 147 + S ++ + V + + LE+ K L + + +D ++ VF G I Sbjct: 83 LVSPWHRMSYFFNPVSNFISFELEKTIKELHEVVGNAAAKDRYI----VF-GVGVTQLIH 137 Query: 148 RLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGH--FHEKTKKYQNVVYMPCGPNNSFFP 205 L + L N+T P +S V+ + F E+TK + Y+ G N + + Sbjct: 138 GLVISLSPNMTATPDAP------ESKVVAHAPFYPVFREQTKYFDKKGYVWAG-NAANYV 190 Query: 206 DLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRS 265 +++ P + SPNNP G L+ A G I+D Y + +P Sbjct: 191 NVS-NPEQYIEMVTSPNNPEG----------LLRHAVIKGCKSIYDMVY--YWPHYTP-- 235 Query: 266 IYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSN----------GFPIINDFH 315 I + I + + SKF G +G R GW++I DE +Y+N G P Sbjct: 236 ---IKYKADEDILLFTMSKFTGHSGSRFGWALIKDESVYNNLLNYMTKNTEGTPRETQLR 292 Query: 316 RIVTTSFNGASNIAQAGGLACLSSGGLKEIR----SVNNYYKENRKILMDTLVSLGLKVY 371 + A Q G + L++ G K++R ++ ++ + L Y Sbjct: 293 SLKVLKEVVAMVKTQKGTMRDLNTFGFKKLRERWVNITALLDQSDRFSYQELPQSEYCNY 352 Query: 372 GGVNAP----YLWVHFKGSKSWDVFNEILENTHIITVPGSGFGPGGEEYLRISGFGRRDH 427 P Y WV + + D + + +N I T G GF Y+R+S +D Sbjct: 353 FRRMRPPSPSYAWVKCEWEEDKDCY-QTFQNGRINTQNGVGF-EASSRYVRLSLIKTQDD 410 Query: 428 IVEASKRLQNFFNTRTK 444 + L++ + K Sbjct: 411 FDQLMYYLKDMVKAKRK 427 >4IX8-A nrPDB Length = 444 Score = 45.1 bits (105), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 48/209 (22%), Positives = 85/209 (40%), Gaps = 21/209 (10%) Query: 105 YRGYGLEQGNKTLRKAIAETFYRDLHVKS--------NEVFVSDGAQSDISRLQLLLGSN 156 + GY G LR+ ++ + R KS N + S +Q+ + L L Sbjct: 102 FNGYPPTVGADNLRQVVSTYWRRFCQTKSRQEALKWENVIITSGVSQAIVLALTALCNEG 161 Query: 157 VTIAVQDPTFPAY--IDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTD 214 I V P+FP Y + S I ++ + +K ++ + G +S T Sbjct: 162 DNILVCAPSFPHYKSVCDSYGIECRYYYLDPSKSWECDLRAAAGMVDS---------HTK 212 Query: 215 VIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFI-EDGSPRSIYEIPGAR 273 +P+NP G SR + ++DF + + +I D YA + +G S+ + Sbjct: 213 AFVIINPSNPCGSNFSRAHVSDIIDFCQQHQIPLISDEIYAEMVLNNGIFTSVADFDTNV 272 Query: 274 EVAIEVSSFSKFAGFTGVRLGWSIIPDEL 302 I + +K+ G R+GWSI+ D + Sbjct: 273 PRLI-LGGTAKYQVCPGWRVGWSILIDPM 300 >2ZYJ-A nrPDB Length = 397 Score = 45.1 bits (105), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 85/346 (24%), Positives = 141/346 (40%), Gaps = 47/346 (13%) Query: 108 YGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQDPTFP 167 Y +G LR +AE + V+ EV ++ G+Q + L+G D P Sbjct: 70 YSPTEGYAPLRAFVAEW----IGVRPEEVLITTGSQQALD----LVGK----VFLDEGSP 117 Query: 168 AYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFC-SPNNPTG 226 +++ +G F + ++ V GP+ ++ R ++ S NPTG Sbjct: 118 VLLEAPSYMGAIQAFRLQGPRFLTVPAGEEGPDLDALEEVLKRERPRFLYLIPSFQNPTG 177 Query: 227 ---YVASRKQLHQLVDFAKTNGSIIIFDSAYAA--FIEDGSPRSIYEIPGAREVA----I 277 + +RK+L Q+V G +++ D AY F E P S++E+ ARE I Sbjct: 178 GLTPLPARKRLLQMV---MERGLVVVEDDAYRELYFGEARLP-SLFEL--AREAGYPGVI 231 Query: 278 EVSSFSKFAGFTGVRLGWSII-PDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLAC 336 + SFSK G+R+ +++ P+ L D H T N Q Sbjct: 232 YLGSFSKVLS-PGLRVAFAVAHPEALQKLVQAKQGADLH---TPMLN------QMLVHEL 281 Query: 337 LSSGGLKEIRSVNNYYKENRKILMDTL---VSLGLKVYGGVNAPYLWVHF-KGSKSWDVF 392 L G + + V Y+E + ++ L V ++ ++W+ KG + +F Sbjct: 282 LKEGFSERLERVRRVYREKAQAMLHALDREVPKEVRYTRPKGGMFVWMELPKGLSAEGLF 341 Query: 393 NEILENTHIITVPGSGF--GPGGEEYLRIS-GFGRRDHIVEASKRL 435 LE ++ VPG F GGE LR+S R+ I E +RL Sbjct: 342 RRALEE-NVAFVPGGPFFANGGGENTLRLSYATLDREGIAEGVRRL 386 >3DYD-A nrPDB Length = 427 Score = 44.7 bits (104), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 83/394 (21%), Positives = 148/394 (37%), Gaps = 40/394 (10%) Query: 64 IEKHPNVQLISLGTGDTTE----PIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRK 119 ++ +PN +ISL GD T P ++T M + Y GY G + R+ Sbjct: 48 VKPNPNKTMISLSIGDPTVFGNLPTDPEVTQAMKDALDS----GKYNGYAPSIGFLSSRE 103 Query: 120 AIAETFY-RDLHVKSNEVFVSDGAQSDISR-LQLLLGSNVTIAVQDPTFPAYIDSSVIIG 177 IA ++ + +++ +V ++ G I L +L I V P F Y + +G Sbjct: 104 EIASYYHCPEAPLEAKDVILTSGCSQAIDLCLAVLANPGQNILVPRPGFSLYKTLAESMG 163 Query: 178 QTGHFHEKTKKYQNVVYMPCGPNNSFFPDLA-----MTPRTDVIFFCSPNNPTGYVASRK 232 + K Y + P S+ DL + +T + +P+NP G V S++ Sbjct: 164 I------EVKLYNLL------PEKSWEIDLKQLEYLIDEKTACLIVNNPSNPCGSVFSKR 211 Query: 233 QLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVR 292 L +++ A I+ D Y + + +K G R Sbjct: 212 HLQKILAVAARQCVPILADEIYGDMVFSDCKYEPLATLSTDVPILSCGGLAKRWLVPGWR 271 Query: 293 LGWSIIPDEL-LYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNY 351 LGW +I D ++ N I D ++ G I Q + L + + ++ Sbjct: 272 LGWILIHDRRDIFGNE---IRDGLVKLSQRILGPCTIVQGALKSILCRTPGEFYHNTLSF 328 Query: 352 YKENRKILMDTLVSL-GLKVYGGVNAPYLWV-----HFKGSKSWDVFNE-ILENTHIITV 404 K N + L ++ GL+ A YL V HF ++ F E ++ + + Sbjct: 329 LKSNADLCYGALAAIPGLRPVRPSGAMYLMVGIEMEHFPEFENDVEFTERLVAEQSVHCL 388 Query: 405 PGSGFGPGGEEYLRISGFGRRDHIVEASKRLQNF 438 P + F ++R+ ++EA R+Q F Sbjct: 389 PATCF--EYPNFIRVVITVPEVMMLEACSRIQEF 420 >3CQ5-A nrPDB Length = 369 Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 28/82 (34%), Positives = 42/82 (51%), Gaps = 5/82 (6%) Query: 214 DVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAR 273 D++F +PNNPTG V S + ++++ A I+I D AYA F S ++ E + Sbjct: 166 DIVFVTTPNNPTGDVTSLDDVERIINVAP---GIVIVDEAYAEFSPSPSATTLLEKYPTK 222 Query: 274 EVAIEVSSFSKFAGFTGVRLGW 295 V + SK F G RLG+ Sbjct: 223 LVV--SRTMSKAFDFAGGRLGY 242 >1IJI-A nrPDB Length = 356 Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 50/195 (25%), Positives = 85/195 (43%), Gaps = 32/195 (16%) Query: 119 KAIAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLGS-----NVTIAVQDPTFPAYIDSS 173 KA+ E + + VK +V VS GA I +LL+ + I PT+ Y S+ Sbjct: 61 KAVIENYAQYAGVKPEQVLVSRGADEGI---ELLIRAFCEPGKDAILYCPPTYGMYSVSA 117 Query: 174 VIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDL-AMTPRTD---VIFFCSPNNPTGYVA 229 IG +Q DL ++ + D V++ CSPNNPTG + Sbjct: 118 ETIGVECRTVPTLDNWQL--------------DLQGISDKLDGVKVVYVCSPNNPTGQLI 163 Query: 230 SRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRS-IYEIPGAREVAIEVSSFSKFAGF 288 + + L++ + +I++ D AY F S + E P +AI + + SK Sbjct: 164 NPQDFRTLLELTR-GKAIVVADEAYIEFCPQASLAGWLAEYP---HLAI-LRTLSKAFAL 218 Query: 289 TGVRLGWSIIPDELL 303 G+R G+++ +E++ Sbjct: 219 AGLRCGFTLANEEVI 233 >3FKD-A nrPDB Length = 350 Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 44/183 (24%), Positives = 82/183 (44%), Gaps = 27/183 (14%) Query: 116 TLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRL-QLLLGSNVTIAVQDPTFPAYIDSSV 174 TLR+ +A + V +N + V++G + ++ Q GS IA+ P+F Y D+ Sbjct: 54 TLRQMLA----KRNSVDNNAILVTNGPTAAFYQIAQAFRGSRSLIAI--PSFAEYEDACR 107 Query: 175 IIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQL 234 + F+ P+N + + D + C+PNNP G + R ++ Sbjct: 108 MYEHEVCFY---------------PSNEDIGEADFS-NMDFCWLCNPNNPDGRLLQRTEI 151 Query: 235 HQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLG 294 +L++ + + D +Y +F + R +I G R+ + V SFS G G+R+G Sbjct: 152 LRLLN--DHPDTTFVLDQSYVSFTTEEVIRPA-DIKG-RKNLVMVYSFSHAYGIPGLRIG 207 Query: 295 WSI 297 + + Sbjct: 208 YIV 210 >3PDX-A nrPDB Length = 402 Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 81/394 (20%), Positives = 148/394 (37%), Gaps = 40/394 (10%) Query: 64 IEKHPNVQLISLGTGDTTE----PIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRK 119 ++ +PN +ISL GD T P ++T M + Y GY G + R+ Sbjct: 25 VKPNPNKTVISLSIGDPTVFGNLPTDPEVTQAMKDALDS----GKYNGYAPSIGYLSSRE 80 Query: 120 AIAETFY-RDLHVKSNEVFVSDGAQSDISR-LQLLLGSNVTIAVQDPTFPAYIDSSVIIG 177 +A ++ + +++ +V ++ G I L +L I + P F Y + +G Sbjct: 81 EVASYYHCPEAPLEAKDVILTSGCSQAIELCLAVLANPGQNILIPRPGFSLYRTLAESMG 140 Query: 178 QTGHFHEKTKKYQNVVYMPCGPNNSFFPDLA-----MTPRTDVIFFCSPNNPTGYVASRK 232 + K Y + P S+ DL + +T + +P+NP G V S++ Sbjct: 141 I------EVKLYNLL------PEKSWEIDLKQLESLIDEKTACLVVNNPSNPCGSVFSKR 188 Query: 233 QLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVR 292 L +++ A+ I+ D Y + + +K G R Sbjct: 189 HLQKILAVAERQCVPILADEIYGDMVFSDCKYEPMATLSTNVPILSCGGLAKRWLVPGWR 248 Query: 293 LGWSIIPDEL-LYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNY 351 LGW +I D ++ N I D ++ G I Q + L + + ++ Sbjct: 249 LGWILIHDRRDIFGNE---IRDGLVKLSQRILGPCTIVQGALKSILQRTPQEFYQDTLSF 305 Query: 352 YKENRKILMDTLVSL-GLKVYGGVNAPYLWV-----HFKGSKSWDVFNE-ILENTHIITV 404 K N + L ++ GL+ A YL V HF ++ F E ++ + + Sbjct: 306 LKSNADLCYGALSAIPGLQPVRPSGAMYLMVGIEMEHFPEFENDVEFTERLIAEQSVHCL 365 Query: 405 PGSGFGPGGEEYLRISGFGRRDHIVEASKRLQNF 438 P + F + R+ ++EA R+Q F Sbjct: 366 PATCF--EYPNFFRVVITVPEVMMLEACSRIQEF 397 >3FDB-A nrPDB Length = 377 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 51/227 (22%), Positives = 89/227 (39%), Gaps = 18/227 (7%) Query: 216 IFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPG-ARE 274 I C+P NP G V + + L++L D A + ++ D +A + DG + A Sbjct: 154 ILLCNPYNPLGMVFAPEWLNELCDLAHRYDARVLVDEIHAPLVFDGQHTVAAGVSDTAAS 213 Query: 275 VAIEVSSFSK---FAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQA 331 V I +++ SK AG ++ +S D + P+I D GAS + Sbjct: 214 VCITITAPSKAWNIAGLKCAQIIFSNPSDAEHWQQLSPVIKD----------GASTLGLI 263 Query: 332 GGLACLSSGGLKEIRSVNNYYKENRKILMDTLVSL--GLKVYGGVNAPYLWVHFKGSKSW 389 A G + Y K N L+ + G K+ +W+ F+ + Sbjct: 264 AAEAAYRY-GTDFLNQEVAYLKNNHDFLLHEIPKRIPGAKITPMQATYLMWIDFRDTTIE 322 Query: 390 DVFNE-ILENTHIITVPGSGFGPGGEEYLRISGFGRRDHIVEASKRL 435 +E +E + G+ FG G + R++ R+ + EA R+ Sbjct: 323 GSPSEFFIEKAKVAMNDGAWFGEDGTGFCRLNFATSREVLEEAIDRM 369 >3GET-A nrPDB Length = 365 Score = 42.7 bits (99), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 41/161 (25%), Positives = 70/161 (43%), Gaps = 21/161 (13%) Query: 204 FPDLAMTPRTDV--IFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAY---AAFI 258 F L T + ++ IF C PNNP G + + + +++ D+AY A+F Sbjct: 143 FKKLYETHKDEIKLIFLCLPNNPLGECLDASEATEFIK-GVNEDCLVVIDAAYNEFASFK 201 Query: 259 EDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIV 318 + E+ + + + +FSK G G+R+G+ I +N II+ F+++ Sbjct: 202 DSKKHLEPCELIKEFDNVLYLGTFSKLYGLGGLRIGYGI-------ANA-NIISAFYKL- 252 Query: 319 TTSFNGASNIAQAGGLACLSSGGLKEIRSVNNY-----YKE 354 FN SN+A +A + E NN+ YKE Sbjct: 253 RAPFN-VSNLALKAAVAAMDDDEFTEKTLENNFSQMELYKE 292 >3B1C-A nrPDB Length = 392 Score = 42.4 bits (98), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 45/227 (19%), Positives = 91/227 (40%), Gaps = 17/227 (7%) Query: 217 FFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEI--PGARE 274 C+P+NP G V R+ L Q+ + + I++ D + G + P ++ Sbjct: 169 LLCNPHNPGGRVWEREVLEQIGHLCQKHHVILVSDEIHQDLTLFGHEHVSFNTVSPDFKD 228 Query: 275 VAIEVSSFSKFAGFTGVRLGWSIIPDELLYSN--GFPIINDFHRIVTTSFNGASNIAQAG 332 A+ +SS +K G + ++II + L + ++N+ H + + + + G Sbjct: 229 FALVLSSATKTFNIAGTKNSYAIIENPTLCAQFKHQQLVNNHHEVSSLGYIATETAYRYG 288 Query: 333 G--LACLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSWD 390 L L + + I+ Y+ + + LKV +W+ F D Sbjct: 289 KPWLVALKAVLEENIQFAVEYFAQE---------APRLKVMKPQGTYLIWLDFSDYGLTD 339 Query: 391 --VFNEILENTHIITVPGSGFGPGGEEYLRISGFGRRDHIVEASKRL 435 +F + + +I GS +G GE + R++ + + E KR+ Sbjct: 340 DALFTLLHDQAKVILNRGSDYGSEGELHARLNIAAPKSLVEEICKRI 386 >1UU1-A nrPDB Length = 335 Score = 42.0 bits (97), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 36/157 (22%), Positives = 67/157 (42%), Gaps = 20/157 (12%) Query: 214 DVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAR 273 DV+F +PNNPTG+V R+++ +++ G+ + D AY F S + Sbjct: 140 DVVFIPNPNNPTGHVFEREEIERIL----KTGAFVALDEAYYEF----HGESYVDFLKKY 191 Query: 274 EVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGG 333 E + +FSK R+G+ + ++ + D + V FN S ++Q Sbjct: 192 ENLAVIRTFSKAFSLAAQRVGYVVASEKFI---------DAYNRVRLPFN-VSYVSQMFA 241 Query: 334 LACLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLKV 370 L + E R+ + E R+ + L +G ++ Sbjct: 242 KVALDHREIFEERT--KFIVEERERMKSALREMGYRI 276 >3FTB-A nrPDB Length = 361 Score = 42.0 bits (97), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 23/85 (27%), Positives = 41/85 (48%), Gaps = 1/85 (1%) Query: 213 TDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGA 272 D + +PNNP G + ++++ ++ A+ II D A+ F D S + EI Sbjct: 145 VDSVIIGNPNNPNGGLINKEKFIHVLKLAEEKKKTIIIDEAFIEFTGDPSSSFVGEIKNY 204 Query: 273 REVAIEVSSFSKFAGFTGVRLGWSI 297 + I + + +KF G+R G+ I Sbjct: 205 SCLFI-IRAMTKFFAMPGIRFGYGI 228 >1M4N-A nrPDB Length = 435 Score = 41.6 bits (96), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 56/247 (22%), Positives = 100/247 (40%), Gaps = 29/247 (11%) Query: 212 RTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYA----------AFIEDG 261 R + +P+NP G +R +L+ L+ F + G +I D Y+ + +E Sbjct: 191 RVKGVLVTNPSNPLGTTMTRNELYLLLSFVEDKGIHLISDEIYSGTAFSSPSFISVMEVL 250 Query: 262 SPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTS 321 R+ E + V S SK G G R+G +YSN ++ ++ +S Sbjct: 251 KDRNCDENSEVWQRVHVVYSLSKDLGLPGFRVG-------AIYSNDDMVVAAATKM--SS 301 Query: 322 FNGASNIAQAGGLACLSSGGLKEIRSVNNY--YKENRKILMDTLVSLGLKVYGGVNAPYL 379 F S+ Q A LS L + N+ K+ +K L+ L G+ G + Sbjct: 302 FGLVSSQTQHLLSAMLSDKKLTKNYIAENHKRLKQRQKKLVSGLQKSGISCLNGNAGLFC 361 Query: 380 WV---HFKGSKSW----DVFNEILENTHIITVPGSGFGPGGEEYLRISGFGRRDHIVE-A 431 WV H S ++ +++ +I+ H+ PGS + R+ + ++ A Sbjct: 362 WVDMRHLLRSNTFEAEMELWKKIVYEVHLNISPGSSCHCTEPGWFRVCFANLPERTLDLA 421 Query: 432 SKRLQNF 438 +RL+ F Sbjct: 422 MQRLKAF 428 >1YAA-A nrPDB Length = 412 Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust. Identities = 29/101 (28%), Positives = 43/101 (42%), Gaps = 7/101 (6%) Query: 201 NSFFPDLAMTPRTDV-IFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIE 259 N F + P + + +NPTG + +Q Q+VD + I +FD+AY F Sbjct: 164 NGFLNAIQKAPEGSIFVLHSCAHNPTGLDPTSEQWVQIVDAIASKNHIALFDTAYQGFAT 223 Query: 260 DGSPRSIYEIPGAREVAIEVS------SFSKFAGFTGVRLG 294 + Y + E VS SF+K AG G R+G Sbjct: 224 GDLDKDAYAVRLGVEKLSTVSPVFVCQSFAKNAGMYGERVG 264 >5DJ3-A nrPDB Length = 376 Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust. Identities = 54/249 (21%), Positives = 101/249 (40%), Gaps = 45/249 (18%) Query: 215 VIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPR----SIYEIP 270 +F +PNNPTG V + ++L +L + +G+++ D+++ F D + ++ + Sbjct: 152 CVFVTTPNNPTGRVLAEERLRRLAEQCAEHGTVLALDTSFRGF--DAAAHYDHYAVLQEA 209 Query: 271 GAREVAIEVSSFSKFAGFTGVRLGWSI------IPDELLYSNGFPIINDFHRIVTTSFNG 324 G R V IE K ++ G + +P E +YS+ I+ ++ Sbjct: 210 GCRWVVIE--DTGKLWPTLDLKAGLLVFSEDIGLPVEKIYSD---ILLGVSPLILALIRE 264 Query: 325 ASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLKVYGGVNAP------- 377 S A GGLA L + + NR ++ L + GV+ P Sbjct: 265 FSRDAADGGLADLHA-----------FILHNRSVVRRALAGV-----EGVSFPDPESRSS 308 Query: 378 YLWVHFKGSKSWDVFNEILENTHIITVPGSGFG----PGGEEYLRISGFGRRDHIVEASK 433 V F G +V+ E L+ H+ +P F G+ +RI+ + + ++ + Sbjct: 309 VERVAFAGRTGTEVWEE-LQRHHVFALPCRQFHWAEPSDGDHMVRIALSRSTEPLEKSVQ 367 Query: 434 RLQNFFNTR 442 L+ TR Sbjct: 368 VLRTVLETR 376 >3AV7-A nrPDB Length = 448 Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust. Identities = 62/315 (19%), Positives = 115/315 (36%), Gaps = 32/315 (10%) Query: 108 YGLEQGNKTLRKAIAETFYRDLHV-KSNEVFVSDGAQSDISRL-QLLLGSNVTIAVQDPT 165 YG +G LR+ + + + + + N++ ++ G+Q + + ++ L + V+ PT Sbjct: 114 YGTTKGFTPLRETLMKWLGKRYGISQDNDIMITSGSQQALDLIGRVFLNPGDIVVVEAPT 173 Query: 166 FPAYIDSSVIIGQTGHFHEKTKKYQNVVY----MPCGPNNSFFPDLAMTPRTDVIFFCSP 221 + A + Q +F+E +Y + M +L + + + P Sbjct: 174 YLAAL-------QAFNFYEP--QYIQIPLDDEGMKVEILEEKLKELKSQGKKVKVVYTVP 224 Query: 222 --NNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEV 279 NP G + + L++ A I++ D Y G+P + I + Sbjct: 225 TFQNPAGVTMNEDRRKYLLELASEYDFIVVEDDPYGELRYSGNPEKKIKALDNEGRVIYL 284 Query: 280 SSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNI-AQAGGLACLS 338 +FSK G R+GW + G P I I S + +N+ Q + Sbjct: 285 GTFSKILA-PGFRIGWMV---------GDPGIIRKMEIAKQSTDLCTNVFGQVVAWRYVD 334 Query: 339 SGGL-KEIRSVNNYYKENRKILMDTLVSL---GLKVYGGVNAPYLWVHFKGSKSWDVFNE 394 G L K I + +YK R +++ L G+K ++WV E Sbjct: 335 GGYLEKHIPEIRKFYKPRRDAMLEALEEFMPEGVKWTKPEGGMFIWVTLPDGIDSKKMLE 394 Query: 395 ILENTHIITVPGSGF 409 + VPG F Sbjct: 395 RAIKKGVAYVPGEAF 409 >3P1T-A nrPDB Length = 337 Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust. Identities = 30/96 (31%), Positives = 43/96 (44%), Gaps = 9/96 (9%) Query: 208 AMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIY 267 A R D + +P+NPTG S +L QL + ++ D Y ++ S R+ Sbjct: 131 AQVSRDDCVVLANPSNPTGQALSAGELDQL----RQRAGKLLIDETY---VDYSSFRARG 183 Query: 268 EIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELL 303 G E+ SFSK G G+RLG P EL+ Sbjct: 184 LAYGENELVFR--SFSKSYGLAGLRLGALFGPSELI 217 >1X0M-A nrPDB Length = 403 Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust. Identities = 62/315 (19%), Positives = 115/315 (36%), Gaps = 32/315 (10%) Query: 108 YGLEQGNKTLRKAIAETFYRDLHV-KSNEVFVSDGAQSDISRL-QLLLGSNVTIAVQDPT 165 YG +G LR+ + + + + + N++ ++ G+Q + + ++ L + V+ PT Sbjct: 69 YGTTKGFTPLRETLMKWLGKRYGISQDNDIMITSGSQQALDLIGRVFLNPGDIVVVEAPT 128 Query: 166 FPAYIDSSVIIGQTGHFHEKTKKYQNVVY----MPCGPNNSFFPDLAMTPRTDVIFFCSP 221 + A + Q +F+E +Y + M +L + + + P Sbjct: 129 YLAAL-------QAFNFYEP--QYIQIPLDDEGMKVEILEEKLKELKSQGKKVKVVYTVP 179 Query: 222 --NNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEV 279 NP G + + L++ A I++ D Y G+P + I + Sbjct: 180 TFQNPAGVTMNEDRRKYLLELASEYDFIVVEDDPYGELRYSGNPEKKIKALDNEGRVIYL 239 Query: 280 SSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNI-AQAGGLACLS 338 +FSK G R+GW + G P I I S + +N+ Q + Sbjct: 240 GTFSKILA-PGFRIGWMV---------GDPGIIRKMEIAKQSTDLCTNVFGQVVAWRYVD 289 Query: 339 SGGL-KEIRSVNNYYKENRKILMDTLVSL---GLKVYGGVNAPYLWVHFKGSKSWDVFNE 394 G L K I + +YK R +++ L G+K ++WV E Sbjct: 290 GGYLEKHIPEIRKFYKPRRDAMLEALEEFMPEGVKWTKPEGGMFIWVTLPDGIDSKKMLE 349 Query: 395 ILENTHIITVPGSGF 409 + VPG F Sbjct: 350 RAIKKGVAYVPGEAF 364 >3L8A-A nrPDB Length = 421 Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust. Identities = 50/232 (21%), Positives = 98/232 (42%), Gaps = 16/232 (6%) Query: 215 VIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGA-- 272 + CSP+NP G V L ++ + K +G I++ D + G+ A Sbjct: 197 IYLLCSPHNPGGRVWDNDDLIKIAELCKKHGVILVSDEIHQDLALFGNTHHSLNTLDASY 256 Query: 273 REVAIEVSSFSKFAGFTGVRLGWSIIPDELLYS--NGFPIINDFHRIVTTSFNGASNIAQ 330 ++ I +SS +K G + ++II +E L + N+ H + T Q Sbjct: 257 KDFTIILSSATKTFNIAGTKNSFAIIQNESLRRKFQYRQLANNQHEVPTVGMIATQAAFQ 316 Query: 331 AGGLACLSSGGLKEIRSVNNYYKENRKILMDTL-VSLGLKVYGGVNAPYLWVHFKG-SKS 388 G L+E+++V + N K+++ L +KV +W+ F + + Sbjct: 317 YG------KPWLEELKTV---IEGNIKLVIKELEAKTKIKVMEPEGTYLVWLDFSAYAIA 367 Query: 389 WDVFNEILEN-THIITVPGSGFGPGGEEYLRISGFGRRDHIVEASKRLQNFF 439 +E L+N ++ G+ FG G+ + R++ ++ + EA R+ + F Sbjct: 368 QPQLSEKLQNEAKVVLNDGAHFGKEGKYFARLNVATPKNTVQEALSRIISVF 419 >6EZL-A nrPDB Length = 404 Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust. Identities = 55/230 (23%), Positives = 94/230 (40%), Gaps = 18/230 (7%) Query: 149 LQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLA 208 L +L + + + DPT+P + +V+ K + Y N C + DL Sbjct: 115 LARVLSRDTPVYISDPTWPNHY--AVMAAANLTDLRKYRYYDNAKR--CIDFDGLLEDLN 170 Query: 209 MTPR-TDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIY 267 P + VI +NPTG + +Q ++++ + I FDSAY + Y Sbjct: 171 GAPEGSIVILHACAHNPTGMDPTHEQWAKILEVFQARRLIPFFDSAYQGYATGSLDNDAY 230 Query: 268 EIPGAREVAIEV---SSFSKFAGFTGVRLG-WSIIPDELLYSNGFPII-NDFHRIVTTSF 322 I +E+ S+SK G R+G SI+ P+I + IV + + Sbjct: 231 SIRLFARQGMEMLLAQSYSKNMGLYAERVGVCSIVTAN---PKKAPLIKSQLETIVRSQY 287 Query: 323 NG-ASNIAQAGGLAC----LSSGGLKEIRSVNNYYKENRKILMDTLVSLG 367 + ++ A+ L L +G +E+R ++ E R+ L D L LG Sbjct: 288 STPPAHGARVAYLVLSDPELRAGWEQELRVMSTRVLEMRQALYDGLKRLG 337 >3TCM-A nrPDB Length = 500 Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust. Identities = 101/433 (23%), Positives = 163/433 (37%), Gaps = 81/433 (18%) Query: 59 RELEHIEKHPNV----QLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGN 114 RE+ + HP++ ++ +L + D+ +QI + + A G Y QG Sbjct: 86 REVLALCDHPDLLQREEIKTLFSADSISR-AKQILAMIPGRATG--------AYSHSQGI 136 Query: 115 KTLRKAIAETFY-RD-LHVKSNEVFVSDGAQSDISRLQLLLGSNVT--IAVQDPTFPAYI 170 LR AIA RD ++++F++DGA + + LL N I V P +P Y Sbjct: 137 HGLRDAIASGIASRDGFPANADDIFLTDGASPGVHLMMQLLIRNEKDGILVPIPQYPLYS 196 Query: 171 DSSVIIGQT---GHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTD-----VIFFCSPN 222 S + G + +E T G S R+ + +P Sbjct: 197 ASIALHGGALVPYYLNESTG---------WGLETSDVKKQLEDARSRGINVRALVVINPG 247 Query: 223 NPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAA--FIEDGSPRSIYEIP-----GAREV 275 NPTG V + + + +V F K G +++ D Y ++++ S +I G ++ Sbjct: 248 NPTGQVLAEENQYDIVKFCKNEGLVLLADEVYQENIYVDNKKFHSFKKIVRSLGYGEEDL 307 Query: 276 A-IEVSSFSK-FAGFTGVRLGWSIIPDELLYSNGF--PIINDFHRIVTTSFNGASNIAQA 331 + S SK + G G R G+ I GF P+ ++I S N SNI Sbjct: 308 PLVSYQSVSKGYYGECGKRGGYFEI-------TGFSAPVREQIYKI--ASVNLCSNIT-G 357 Query: 332 GGLACLSSGGLKEIRSVNNYYKENRKILMDTLVSL------------GLKVYGGVNAPYL 379 LA L K YK + ++ +L G+ A Y+ Sbjct: 358 QILASLVMNPPKASDESYASYKAEKDGILASLARRAKALEHAFNKLEGITCNEAEGAMYV 417 Query: 380 WVHF-----------KGSKSWDVFN--EILENTHIITVPGSGFGP-GGEEYLRISGFGRR 425 + +K+ D F +LE+T I+ VPGSGFG G + R + + Sbjct: 418 FPQICLPQKAIEAAKAANKAPDAFYALRLLESTGIVVVPGSGFGQVPGTWHFRCTILPQE 477 Query: 426 DHIVEASKRLQNF 438 D I R F Sbjct: 478 DKIPAVISRFTVF 490 >2ZC0-A nrPDB Length = 407 Score = 38.5 bits (88), Expect = 0.007, Method: Compositional matrix adjust. Identities = 95/402 (23%), Positives = 156/402 (38%), Gaps = 60/402 (14%) Query: 70 VQLISLGTGDTT-EPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETF--Y 126 V+LISL GD E IP + ++ L Y G LR+ +A Y Sbjct: 34 VKLISLAAGDPDPELIPRAVLGEIAK--EVLEKEPKSVMYTPANGIPELREELAAFLKKY 91 Query: 127 RDLHVKSNEVFVSDGAQSDISRL-QLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEK 185 L V + ++ G + L ++L+ + ++P+ YI++ + Q G Sbjct: 92 DHLEVSPENIVITIGGTGALDLLGRVLIDPGDVVITENPS---YINTLLAFEQLGA---- 144 Query: 186 TKKYQNVVYMPCGPNNSFFPDL---------AMTPRTDVIF-FCSPNNPTGYVASRKQLH 235 K + V P N+ DL A + +I+ + NP G S ++ Sbjct: 145 --KIEGV---PVD-NDGMRVDLLEEKIKELKAKGQKVKLIYTIPTGQNPMGVTMSMERRK 198 Query: 236 QLVDFAKTNGSIIIFDSAYAAFIEDGS---PRSIYEIPGAREVAIEVSSFSKFAGFTGVR 292 L++ A +II D+AY +G P + G VA + SK G TG R Sbjct: 199 ALLEIASKYDLLIIEDTAYNFMRYEGGDIVPLKALDNEGRVIVA---GTLSKVLG-TGFR 254 Query: 293 LGWSIIPDELLYS---NGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKE--IRS 347 +GW I E+L PI DF A I+Q L L G ++ + Sbjct: 255 IGWIIAEGEILKKVLMQKQPI--DFC---------APAISQYIALEYLKRGYFEKYHLEG 303 Query: 348 VNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHF---KGSKSWDVFNEILENTHIITV 404 YKE R I++ L + ++V F +G+ NE++E ++ V Sbjct: 304 ALLGYKEKRDIMLKALENHLPNAEFTKPIAGMFVMFFLPEGADGISFANELMEREGVVVV 363 Query: 405 PGSGF--GPGGEEYLRISGFGR--RDHIVEASKRLQNFFNTR 442 PG F G+ +R++ F R ++ I K+L + + Sbjct: 364 PGKPFYTDESGKNAIRLN-FSRPSKEEIPIGIKKLAKLYKEK 404 >3MEB-A nrPDB Length = 448 Score = 38.1 bits (87), Expect = 0.008, Method: Compositional matrix adjust. Identities = 26/93 (27%), Positives = 39/93 (41%), Gaps = 4/93 (4%) Query: 206 DLAMTPRTDV-IFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPR 264 D+ P + +F +NP+G + Q +L+ K I FDSAY F Sbjct: 195 DIQSAPEKSIFLFHACAHNPSGIDFTEAQWKELLPIMKEKKHIAFFDSAYQGFATGSFEA 254 Query: 265 SIYEIPGAREVAIEV---SSFSKFAGFTGVRLG 294 + + + +EV SFSK G G R+G Sbjct: 255 DAFAVRMFVDAGVEVLVAQSFSKNFGLYGERIG 287 >2ZY3-A nrPDB Length = 546 Score = 37.7 bits (86), Expect = 0.009, Method: Compositional matrix adjust. Identities = 42/154 (27%), Positives = 68/154 (44%), Gaps = 21/154 (13%) Query: 148 RLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPN-NSFFPD 206 +L LL + +A+ P F YI+ E + V + P+ N +PD Sbjct: 186 KLNGLLKAGDKVAIGMPVFTPYIE----------IPELAQYALEEVAINADPSLNWQYPD 235 Query: 207 LAMTPRTD---VIFFC-SPNNPTGYVASRKQLHQLVDFAKTNGS--IIIFDSAYAAFIED 260 + D IFFC +P+NP ++ L ++ + + +I+ D Y F +D Sbjct: 236 SELDKLKDPAIKIFFCVNPSNPPSVKMDQRSLERVRNIVAEHRPDLMILTDDVYGTFADD 295 Query: 261 GSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLG 294 +S++ I E + V SFSK+ G TG RLG Sbjct: 296 F--QSLFAI--CPENTLLVYSFSKYFGATGWRLG 325 >1D2F-A nrPDB Length = 390 Score = 37.7 bits (86), Expect = 0.010, Method: Compositional matrix adjust. Identities = 15/53 (28%), Positives = 25/53 (47%) Query: 211 PRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSP 263 P ++ CSP NPTG V + +L + D + +G +I D + + P Sbjct: 161 PECKIMLLCSPQNPTGKVWTCDELEIMADLCERHGVRVISDEIHMDMVWGEQP 213 >1IAY-A nrPDB Length = 428 Score = 37.0 bits (84), Expect = 0.019, Method: Compositional matrix adjust. Identities = 55/247 (22%), Positives = 98/247 (39%), Gaps = 39/247 (15%) Query: 216 IFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPR--SIYEIPGAR 273 + +P+NP G + L ++ F + ++ D YAA + D +P+ SI EI + Sbjct: 192 LILTNPSNPLGTTLDKDTLKSVLSFTNQHNIHLVCDEIYAATVFD-TPQFVSIAEILDEQ 250 Query: 274 EVAIE-------VSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGAS 326 E+ V S SK G G R+G ++YS ++N ++ +SF S Sbjct: 251 EMTYCNKDLVHIVYSLSKDMGLPGFRVG-------IIYSFNDDVVNCARKM--SSFGLVS 301 Query: 327 NIAQAGGLACLSSGGLKEIRSVNNYYKEN-------RKILMDTLVSLGLKVYGGVNAPYL 379 Q A LS + + V+N+ +E+ K + L +G+K + Sbjct: 302 TQTQYFLAAMLS-----DEKFVDNFLRESAMRLGKRHKHFTNGLEVVGIKCLKNNAGLFC 356 Query: 380 WVHFKGSKSWDVFNE-------ILENTHIITVPGSGFGPGGEEYLRISGFGRRDHIVE-A 431 W+ + F+ I+ + + PGS F + R+ D V+ A Sbjct: 357 WMDLRPLLRESTFDSEMSLWRVIINDVKLNVSPGSSFECQEPGWFRVCFANMDDGTVDIA 416 Query: 432 SKRLQNF 438 R++ F Sbjct: 417 LARIRRF 423 >1TAR-A nrPDB Length = 401 Score = 36.6 bits (83), Expect = 0.025, Method: Compositional matrix adjust. Identities = 25/93 (26%), Positives = 38/93 (40%), Gaps = 4/93 (4%) Query: 206 DLAMTPRTDVIFF-CSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPR 264 D++ P +I +NPTG ++Q +L K + FD AY F R Sbjct: 168 DISKIPEKSIILLHACAHNPTGVDPRQEQWKELASVVKKRNLLAYFDMAYQGFASGDINR 227 Query: 265 SIYEIPGAREVAIEV---SSFSKFAGFTGVRLG 294 + + E I+V S++K G G R G Sbjct: 228 DAWALRHFIEQGIDVVLSQSYAKNMGLYGERAG 260 >3NRA-A nrPDB Length = 407 Score = 36.6 bits (83), Expect = 0.026, Method: Compositional matrix adjust. Identities = 24/82 (29%), Positives = 37/82 (45%), Gaps = 2/82 (2%) Query: 215 VIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGA-- 272 V F +PNNP G V S +++ Q+ A G+ +I D Y+ G+ + A Sbjct: 182 VFLFSNPNNPAGVVYSAEEIGQIAALAARYGATVIADQLYSRLRYAGASYTHLRAEAAVD 241 Query: 273 REVAIEVSSFSKFAGFTGVRLG 294 E + + SK +G RLG Sbjct: 242 AENVVTIMGPSKTESLSGYRLG 263 >3VK2-A nrPDB Length = 398 Score = 36.2 bits (82), Expect = 0.027, Method: Compositional matrix adjust. Identities = 17/49 (34%), Positives = 29/49 (59%), Gaps = 3/49 (6%) Query: 206 DLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAY 254 + AMTP T VI+F SP NP ++A + + A+ +G+ ++ D+ Y Sbjct: 144 EAAMTPATRVIYFESPANPNMHMAD---IAGVAKIARKHGATVVVDNTY 189 >1VP4-A nrPDB Length = 425 Score = 36.2 bits (82), Expect = 0.031, Method: Compositional matrix adjust. Identities = 54/241 (22%), Positives = 94/241 (39%), Gaps = 50/241 (20%) Query: 222 NNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDG-SPRSIYEIPGAREVAIEVS 280 +NP G S ++ LV+ A+ I+ D Y A +G + I++I G V + ++ Sbjct: 198 HNPAGVTTSLEKRKALVEIAEKYDLFIVEDDPYGALRYEGETVDPIFKIGGPERVVL-LN 256 Query: 281 SFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSG 340 +FSK G+R+G +V S I QA A L S Sbjct: 257 TFSKVLA-PGLRIG----------------------MVAGSKEFIRKIVQAKQSADLCSP 293 Query: 341 G---------------LKEIRSVNNYYKENRKILMDTLVSL-----GLKVYGGVNAPYLW 380 L++++ Y+ R ++++ L G+K ++W Sbjct: 294 AITHRLAARYLERYDLLEQLKPTIELYRRKRTVMLNALEEYFSDIPGVKWVKSEGGLFIW 353 Query: 381 VHF-KGSKSWDVFNEILENTHIITVPGSGFGPGGE--EYLRIS-GFGRRDHIVEASKRLQ 436 + +G +W++F E + + VPG F E +R+S + IVE KRL+ Sbjct: 354 LTLPEGFDTWEMF-EYAKRKKVFYVPGRVFKVYDEPSPSMRLSFCLPPDEKIVEGIKRLR 412 Query: 437 N 437 Sbjct: 413 E 413 >3E9A-A nrPDB Length = 286 Score = 35.8 bits (81), Expect = 0.040, Method: Compositional matrix adjust. Identities = 52/221 (23%), Positives = 87/221 (39%), Gaps = 57/221 (25%) Query: 100 STVEGYRGYGLEQGNKTLRKAIAETF----YRDLHVKSNEVFVSD-----------GAQS 144 S+V YRG GLE+G K ++ + ETF D+H ++ V+D Q+ Sbjct: 67 SSVHSYRGPGLEEGMKIFQE-LKETFGVKIITDVHTEAQAQPVADVVDVIQLPAFLARQT 125 Query: 145 DISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFF 204 D+ ++ + + I V+ P F + GQ G+ EK + CG Sbjct: 126 DL--VEAMAKTGAVINVKKPQFMSP-------GQVGNIVEK--------FAECG------ 162 Query: 205 PDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFA----KTNGSIIIFDSAYAAFIED 260 D + C + GY + ++ F +NGS IIFD ++ + D Sbjct: 163 --------NDKVILCERGSCHGY---DNLVVDMLGFGVMKQASNGSPIIFDVTHSLQMRD 211 Query: 261 GSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDE 301 S + G RE +E++ G G+ + PD+ Sbjct: 212 PSGAASG---GRREQTVELAKAGLATGIAGLFIEAHPNPDK 249 >5Z0Q-C nrPDB Length = 389 Score = 34.7 bits (78), Expect = 0.089, Method: Compositional matrix adjust. Identities = 35/158 (22%), Positives = 65/158 (41%), Gaps = 19/158 (12%) Query: 209 MTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFI-EDGSPRSIY 267 M+ ++ C+P+NP G V RK+L + FA+ + ++ D + + E G + Sbjct: 162 MSGNEKLLLLCNPHNPGGTVYRRKELEAQLRFAQRHDLLVCSDEIHCDLVLEPG----VQ 217 Query: 268 EIP------GAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTS 321 IP A + +I + S SK G+ ++IP+ L + F+R+ Sbjct: 218 HIPFASLSDDAAQRSITLMSPSKSFNIAGLGASLAVIPNPELRAR-------FNRMRKGM 270 Query: 322 FNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKIL 359 +A A G + + +Y + NR +L Sbjct: 271 VPDVDVLAYVAASAAWREGQ-PWLDAQLDYLRANRDML 307 >2ZY2-A nrPDB Length = 544 Score = 34.3 bits (77), Expect = 0.12, Method: Compositional matrix adjust. Identities = 42/176 (23%), Positives = 79/176 (44%), Gaps = 27/176 (15%) Query: 132 KSNEVFVSDGAQSDIS------RLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEK 185 +S ++F +G + ++ R+ LL + +A+ P F YI+ I + + K Sbjct: 163 ESVDLFAVEGGTAAMAYIFESLRISGLLKAGDKVAIGMPVFTPYIE----IPELAQYDLK 218 Query: 186 TKKYQNVVYMPCGPNNSF-FPDLAMTPRTD---VIFFC-SPNNPTGYVASRKQLHQL--V 238 V + P+N + + D + D IFFC +P+NP ++ L ++ + Sbjct: 219 E------VPIHADPDNGWQYSDAELDKLKDPDVKIFFCVNPSNPPSVKMDQRSLDRVRAI 272 Query: 239 DFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLG 294 + +I+ D Y F ++ +S++ + + V SFSK+ G TG RLG Sbjct: 273 VAEQRPDLLILTDDVYGTFADEF--QSLFSV--CPRNTLLVYSFSKYFGATGWRLG 324 >3IF2-A nrPDB Length = 444 Score = 33.9 bits (76), Expect = 0.13, Method: Compositional matrix adjust. Identities = 83/348 (23%), Positives = 129/348 (37%), Gaps = 51/348 (14%) Query: 100 STVEGYRGYGLEQGNKTLRKAIAETFYR--DLHVKSNEVFVSDGAQSDISRL-QLLLGSN 156 S + Y QG+ A+ F R D ++ S + +++G+Q+ L L G+ Sbjct: 71 SAIISMANYSNPQGDSAFIDALVGFFNRHYDWNLTSENIALTNGSQNAFFYLFNLFGGAF 130 Query: 157 VTIAVQD------------PTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSF- 203 V QD P P YI S + + HF V + G F Sbjct: 131 VNEHSQDKESKSVDKSILLPLTPEYIGYSDVHVEGQHFAAVLPHIDEVTH--DGEEGFFK 188 Query: 204 ----FPDLAMTP-----RTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAY 254 F L P R I P NPTG V + +++ L + AK +I D+AY Sbjct: 189 YRVDFEALENLPALKEGRIGAICCSRPTNPTGNVLTDEEMAHLAEIAKRYDIPLIIDNAY 248 Query: 255 AAFIEDGSPRSIYEIP--GAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIIN 312 P IY I S SK G G+R G II + +N Sbjct: 249 GMPF----PNIIYSDAHLNWDNNTILCFSLSKI-GLPGMRTG--IIVADAKVIEAVSAMN 301 Query: 313 DFHRIVTTSFNGASNIAQAGGLACLSSGGLKEI--RSVNNYYKENR----KILMDTLVSL 366 + T F A IA +++ +K++ + +Y++ K+L L Sbjct: 302 AVVNLAPTRFGAA--IAT----PLVANDRIKQLSDNEIKPFYQKQATLAVKLLKQALGDY 355 Query: 367 GLKVYGGVNAPYLWVHFKGS--KSWDVFNEILENTHIITVPGSGFGPG 412 L ++ A +LW+ FK + D++ E L+ + VP F PG Sbjct: 356 PLMIHKPEGAIFLWLWFKDLPISTLDLY-ERLKAKGTLIVPSEYFFPG 402 >1AY8-A nrPDB Length = 394 Score = 33.9 bits (76), Expect = 0.14, Method: Compositional matrix adjust. Identities = 44/202 (21%), Positives = 75/202 (37%), Gaps = 23/202 (11%) Query: 68 PNVQLISLGTG---DTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAET 124 P I LG G D T P H + + E + Y G +KA+ E Sbjct: 24 PRQGKIDLGVGVYKDATGHTPIMRAVHAAE--QRMLETETTKTYAGLSGEPEFQKAMGEL 81 Query: 125 FYRD-LHVKSNEVFVS---DGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIG--- 177 D L ++ + GA L + ++ + V DPT+P ++ +G Sbjct: 82 ILGDGLKSETTATLATVGGTGALRQALELARMANPDLRVFVSDPTWPNHVSIMNFMGLPV 141 Query: 178 QTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFF--CSPNNPTGYVASRKQLH 235 QT + + + + M DLA + D++ C +NPTG + Q Sbjct: 142 QTYRYFDAETRGVDFEGMKA--------DLAAAKKGDMVLLHGCC-HNPTGANLTLDQWA 192 Query: 236 QLVDFAKTNGSIIIFDSAYAAF 257 ++ + G++ + D AY F Sbjct: 193 EIASILEKTGALPLIDLAYQGF 214 >1C7O-A nrPDB Length = 399 Score = 33.9 bits (76), Expect = 0.16, Method: Compositional matrix adjust. Identities = 13/53 (24%), Positives = 27/53 (50%) Query: 216 IFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYE 268 + FCSP+NP G V + +L ++ D + ++ D + I G ++++ Sbjct: 168 LLFCSPHNPVGRVWKKDELQKIKDIVLKSDLMLWSDEIHFDLIMPGYEHTVFQ 220 >1KNR-A nrPDB Length = 540 Score = 33.5 bits (75), Expect = 0.21, Method: Compositional matrix adjust. Identities = 27/102 (26%), Positives = 45/102 (44%), Gaps = 23/102 (22%) Query: 16 SPSKIPKASLDFEMKKLGGSTKLVRNVNLEKLKNNYLFPEINRRELEHIEKH-PNV--QL 72 +P I ++D EMK+LG + +F +I+ + + I +H P + +L Sbjct: 288 APRDIVARAIDHEMKRLGA---------------DCMFLDISHKPADFIRQHFPMIYEKL 332 Query: 73 ISLGTGDTTEPIPEQITSHMSNFA-----HGLSTVEGYRGYG 109 + LG T EP+P +H + HG + VEG G Sbjct: 333 LGLGIDLTQEPVPIVPAAHYTCGGVMVDDHGRTDVEGLYAIG 374 >3G7Q-A nrPDB Length = 417 Score = 33.1 bits (74), Expect = 0.24, Method: Compositional matrix adjust. Identities = 53/222 (23%), Positives = 90/222 (40%), Gaps = 30/222 (13%) Query: 204 FPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSP 263 F L + T +I P NPTG V + ++L +L A + ++ D+AY G P Sbjct: 172 FEHLHIGEETGMICVSRPTNPTGNVITDEELMKLDRLANQHNIPLVIDNAY------GVP 225 Query: 264 RSIYEIPGAREV----AIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVT 319 AR + I S SK G G R G I D+ + + I + + I++ Sbjct: 226 FPGIIFSEARPLWNPNIILCMSLSKL-GLPGSRCGIIIANDKTITA-----IANMNGIIS 279 Query: 320 TSFNG-----ASNIAQAGGLACLSSGGLKEIRSVNNYYKENRK---ILMDTLVSLGLKVY 371 + G + + L LS +K YY+ ++ I+ L ++ Sbjct: 280 LAPGGMGPAMMCEMIKRNDLLRLSETVIKPF-----YYQRVQQTIAIIRRYLSEERCLIH 334 Query: 372 GGVNAPYLWVHFKGSK-SWDVFNEILENTHIITVPGSGFGPG 412 A +LW+ FK + ++ + L+ ++ VPG F PG Sbjct: 335 KPEGAIFLWLWFKDLPITTELLYQRLKARGVLMVPGHYFFPG 376 >3PD6-B nrPDB Length = 401 Score = 33.1 bits (74), Expect = 0.25, Method: Compositional matrix adjust. Identities = 23/93 (24%), Positives = 36/93 (38%), Gaps = 4/93 (4%) Query: 206 DLAMTPRTDVIFF-CSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPR 264 D++ P V+ +NPTG +Q ++ K FD AY F + Sbjct: 168 DISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDK 227 Query: 265 SIYEIPGAREVAIEVS---SFSKFAGFTGVRLG 294 + + E I V S++K G G R+G Sbjct: 228 DAWAVRHFIEQGINVCLCQSYAKNMGLYGERVG 260 >3IHJ-A nrPDB Length = 498 Score = 33.1 bits (74), Expect = 0.25, Method: Compositional matrix adjust. Identities = 42/208 (20%), Positives = 80/208 (38%), Gaps = 24/208 (11%) Query: 108 YGLEQGNKTLRKAIAETFYRD---LHVKSNEVFVSDGAQSDISRLQLLL-----GSNVTI 159 Y QG +R+ +A R + + ++++ GA IS + +L S + Sbjct: 125 YSASQGVNCIREDVAAYITRRDGGVPADPDNIYLTTGASDGISTILKILVSGGGKSRTGV 184 Query: 160 AVQDPTFPAY--IDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIF 217 + P +P Y + S + Q ++ ++ +N + + V+ Sbjct: 185 MIPIPQYPLYSAVISELDAIQVNYYLDE----ENCWALNVNELRRAVQEAKDHCDPKVLC 240 Query: 218 FCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPR------SIYEIPG 271 +P NPTG V SRK + ++ FA ++ D Y + R +YE+ Sbjct: 241 IINPGNPTGQVQSRKCIEDVIHFAWEEKLFLLADEVYQDNVYSPDCRFHSFKKVLYEMGP 300 Query: 272 AREVAIEVSSFSK----FAGFTGVRLGW 295 +E++SF + G G R G+ Sbjct: 301 EYSSNVELASFHSTSKGYMGECGYRGGY 328 >3F6T-A nrPDB Length = 533 Score = 33.1 bits (74), Expect = 0.25, Method: Compositional matrix adjust. Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 5/85 (5%) Query: 211 PRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSI-IIFDSAYAAFIEDGSPRSIYEI 269 P + +P NPT L+ + + N + II D Y AF+ + +SIY + Sbjct: 243 PSIKALIVVNPTNPTSKEFDTNALNAIKQAVEKNPKLMIISDEVYGAFVPNF--KSIYSV 300 Query: 270 PGAREVAIEVSSFSKFAGFTGVRLG 294 + V S+SK G TG RLG Sbjct: 301 VPYNTML--VYSYSKLFGCTGWRLG 323 >3FDD-A nrPDB Length = 533 Score = 33.1 bits (74), Expect = 0.26, Method: Compositional matrix adjust. Identities = 42/150 (28%), Positives = 63/150 (42%), Gaps = 21/150 (14%) Query: 152 LLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPN-NSFFPDLAMT 210 LL + +A+ P F YI+ E + V + P N +PD + Sbjct: 190 LLKAGDKVAIGMPVFTPYIE----------IPELAQYALEEVAINADPALNWQYPDSELD 239 Query: 211 PRTD---VIFFC-SPNNPTGYVASRKQLHQLVDFAKTNGS--IIIFDSAYAAFIEDGSPR 264 D IFFC +P+NP + L ++ + +I+ D Y F DG + Sbjct: 240 KLKDPAIKIFFCVNPSNPPSVKMDERSLERVRKIVAEHRPDLMILTDDVYGTF-ADGF-Q 297 Query: 265 SIYEIPGAREVAIEVSSFSKFAGFTGVRLG 294 S++ I A + V SFSK+ G TG RLG Sbjct: 298 SLFAICPAN--TLLVYSFSKYFGATGWRLG 325 >3BWN-A nrPDB Length = 391 Score = 33.1 bits (74), Expect = 0.27, Method: Compositional matrix adjust. Identities = 23/82 (28%), Positives = 40/82 (48%), Gaps = 12/82 (14%) Query: 220 SPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEV 279 SPNNP G + +V+ + + +I D AY + +P I ++ I + Sbjct: 165 SPNNPDGTIR-----ETVVNRPDDDEAKVIHDFAY--YWPHYTP-----ITRRQDHDIML 212 Query: 280 SSFSKFAGFTGVRLGWSIIPDE 301 +FSK G G R+GW+++ D+ Sbjct: 213 FTFSKITGHAGSRIGWALVKDK 234 >3K7Y-A nrPDB Length = 405 Score = 32.7 bits (73), Expect = 0.33, Method: Compositional matrix adjust. Identities = 28/96 (29%), Positives = 35/96 (36%), Gaps = 4/96 (4%) Query: 203 FFPDLAMTPR-TDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDG 261 F DL P + VI S NP K ++++ +IIFD AY F Sbjct: 164 FLNDLRNIPNGSSVILQISCYNPCSVNIEEKYFDEIIEIVLHKKHVIIFDIAYQGFGHTN 223 Query: 262 SPRSIYEIPGAREVAIEVS---SFSKFAGFTGVRLG 294 + I E I S SFSK G R G Sbjct: 224 LEEDVLLIRKFEEKNIAFSVCQSFSKNMSLYGERAG 259 >3II0-A nrPDB Length = 422 Score = 32.7 bits (73), Expect = 0.34, Method: Compositional matrix adjust. Identities = 28/96 (29%), Positives = 36/96 (37%), Gaps = 4/96 (4%) Query: 203 FFPDLAMTPR-TDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDG 261 F DL P + V+ +NPTG + +Q Q+ K FDSAY F Sbjct: 162 FLNDLENAPEFSIVVLHACAHNPTGIDPTPEQWKQIASVMKHRFLFPFFDSAYQGFASGN 221 Query: 262 SPRSIYEIPGAREVAIE---VSSFSKFAGFTGVRLG 294 R + I E SFSK G R+G Sbjct: 222 LERDAWAIRYFVSEGFEFFCAQSFSKNFGLYNERVG 257 >3EUC-A nrPDB Length = 367 Score = 32.7 bits (73), Expect = 0.37, Method: Compositional matrix adjust. Identities = 22/83 (26%), Positives = 39/83 (46%), Gaps = 7/83 (8%) Query: 215 VIFFCSPNNPTGYVASRKQLHQLVDFAKTN--GSIIIFDSAYAAFIEDGSPRSIYEIPGA 272 +++ PNNPTG + + +V A+ + S+++ D AY F ++ + + G Sbjct: 160 IVYLAYPNNPTGNLFDAADMEAIVRAAQGSVCRSLVVVDEAYQPFAQESWMSRLTDF-GN 218 Query: 273 REVAIEVSSFSKFAGFTGVRLGW 295 V VS G G+RLG+ Sbjct: 219 LLVMRTVSKL----GLAGIRLGY 237 >2X5F-A nrPDB Length = 430 Score = 32.3 bits (72), Expect = 0.45, Method: Compositional matrix adjust. Identities = 17/59 (28%), Positives = 30/59 (50%), Gaps = 6/59 (10%) Query: 215 VIFFCSPNNPTGYVASRKQLHQLVDFAK------TNGSIIIFDSAYAAFIEDGSPRSIY 267 ++ PNNPTGY + K++ +V+ K T ++ D+ Y F ED +S++ Sbjct: 192 IMILNYPNNPTGYTPTHKEVTTIVEAIKALANKGTKVIAVVDDAYYGLFYEDVYTQSLF 250 >3G0T-A nrPDB Length = 437 Score = 32.3 bits (72), Expect = 0.47, Method: Compositional matrix adjust. Identities = 37/141 (26%), Positives = 62/141 (43%), Gaps = 18/141 (12%) Query: 216 IFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAY--AAFIED----GSPRSIYEI 269 I + +PNNPT + ++L + + A + I+I D AY F +D G P + Sbjct: 186 IIYSNPNNPTWQCMTDEELRIIGELATKHDVIVIEDLAYFGMDFRKDYSHPGEPLYQPSV 245 Query: 270 PGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIIND-FHRI----------V 318 + I S SK + G R+G +I + LY +P + + F R+ + Sbjct: 246 ANYTDNYILALSSSKAFSYAGQRIGVLMISGK-LYEREYPDLEESFGRLRFGEALSSSAL 304 Query: 319 TTSFNGASNIAQAGGLACLSS 339 +GA++ AQ G A L + Sbjct: 305 YALSSGATHSAQWGMAAMLKA 325 >4WBT-A nrPDB Length = 376 Score = 31.6 bits (70), Expect = 0.84, Method: Compositional matrix adjust. Identities = 23/88 (26%), Positives = 42/88 (47%), Gaps = 12/88 (13%) Query: 215 VIFFCSPNNPTGYVASRKQLHQLVDFAKT--NGSIIIFDSAYAAFI-EDGSP--RSIYEI 269 +++ +P+NP G S ++V FA+ ++++ D AY D P S+ + Sbjct: 162 LVYLANPDNPMG---SWWPAERVVAFAQALPETTLLVLDEAYCETAPRDALPPIESLIDK 218 Query: 270 PGAREVAIEVSSFSKFAGFTGVRLGWSI 297 P I +FSK G G R+G+++ Sbjct: 219 PNV----IRARTFSKAYGLAGARIGYTL 242 >3U14-A nrPDB Length = 535 Score = 31.2 bits (69), Expect = 0.86, Method: Compositional matrix adjust. Identities = 23/83 (27%), Positives = 38/83 (45%), Gaps = 4/83 (4%) Query: 212 RTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPG 271 R +F+ +N V S+ Q +++ F N + +S +++ G + YE PG Sbjct: 178 RDPKVFWHEDSNQWIMVVSKSQEYKIQIFGSANLKNWVLNSNFSS----GYYGNQYECPG 233 Query: 272 AREVAIEVSSFSKFAGFTGVRLG 294 EV IE S SK+ F + G Sbjct: 234 LIEVPIENSDKSKWVMFLAINPG 256 >1WST-A nrPDB Length = 417 Score = 31.2 bits (69), Expect = 0.92, Method: Compositional matrix adjust. Identities = 35/155 (22%), Positives = 59/155 (38%), Gaps = 13/155 (8%) Query: 212 RTDVIFFCSP-NNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIP 270 R +++ S NP G S + +L++ A +I+ D Y+ G P + Sbjct: 182 RVKIVYTVSTFQNPAGVTMSVDRRKKLLELANEYDFLIVEDGPYSELRYSGEPTPPIKHF 241 Query: 271 GAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASN-IA 329 I + +FSK G R+GW P + I S + +N Sbjct: 242 DDYGRVIYLGTFSKILA-PGFRIGW---------VAAHPHLIRKMEIAKQSIDLCTNTFG 291 Query: 330 QAGGLACLSSGGLKE-IRSVNNYYKENRKILMDTL 363 QA + +G L E I + +YK R +++ L Sbjct: 292 QAIAWKYVENGYLDEHIPKIIEFYKPRRDAMLEAL 326 >5TON-A nrPDB Length = 414 Score = 31.2 bits (69), Expect = 0.94, Method: Compositional matrix adjust. Identities = 31/129 (24%), Positives = 50/129 (38%), Gaps = 13/129 (10%) Query: 203 FFPDLAMTPRTDV-IFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDG 261 F DL P + + +NPTG + +Q Q+ K FDSAY F Sbjct: 175 FLSDLENAPEFSIFVLHACAHNPTGTDPTPEQWKQIASVMKRRFLFPFFDSAYQGFASGN 234 Query: 262 SPRSIYEIPGAREVAIEV---SSFSKFAGFTGVRLGWSII----PDELLYSNGFPIINDF 314 + + I E+ SFSK G R+G + PD +L +++ Sbjct: 235 LEKDAWAIRYFVSEGFELFCAQSFSKNFGLYNERVGNLTVVAKEPDSILR-----VLSQM 289 Query: 315 HRIVTTSFN 323 +IV +++ Sbjct: 290 QKIVRVTWS 298 >4WB0-B nrPDB Length = 414 Score = 31.2 bits (69), Expect = 0.98, Method: Compositional matrix adjust. Identities = 36/142 (25%), Positives = 54/142 (38%), Gaps = 12/142 (8%) Query: 159 IAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPN-NSFFPDLAMTPRTDVIF 217 I + DPT+P + I+ G +T Y + + G + D+ P V Sbjct: 134 IYLADPTWPNHYS---IVKAAGWKDIRTYAYYD--HKTLGLDFEGMKKDILAAPDGSVFL 188 Query: 218 F--CSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREV 275 C+ +NPTG S++Q +++ + FDSAY + Y Sbjct: 189 LHQCA-HNPTGVDPSQEQWNEIASLMLAKHHQVFFDSAYQGYASGSLDTDAYAARLFARR 247 Query: 276 AIEV---SSFSKFAGFTGVRLG 294 IEV SFSK G R G Sbjct: 248 GIEVLLAQSFSKNMGLYSERAG 269 >4F5M-A nrPDB Length = 406 Score = 30.8 bits (68), Expect = 1.1, Method: Compositional matrix adjust. Identities = 22/82 (26%), Positives = 34/82 (41%), Gaps = 2/82 (2%) Query: 215 VIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIE--DGSPRSIYEIPGA 272 V+F +NPTG + +Q L + G + +FD AY F + + Sbjct: 185 VLFHGCCHNPTGIDPTLEQWQTLAQLSVEKGWLPLFDFAYQGFARGLEEDAEGLRAFAAM 244 Query: 273 REVAIEVSSFSKFAGFTGVRLG 294 + I SS+SK G R+G Sbjct: 245 HKELIVASSYSKNFGLYNERVG 266 >5EJ0-A nrPDB Length = 237 Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust. Identities = 19/42 (45%), Positives = 24/42 (57%), Gaps = 3/42 (7%) Query: 318 VTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKIL 359 VTT+ N I ++GGL SSG EI + N K NR+IL Sbjct: 189 VTTALNIVDEIIKSGGL---SSGFYFEIARIENEMKINRQIL 227 >4RKC-A nrPDB Length = 398 Score = 30.4 bits (67), Expect = 1.5, Method: Compositional matrix adjust. Identities = 26/88 (29%), Positives = 42/88 (47%), Gaps = 7/88 (7%) Query: 212 RTDVIFF--CSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEI 269 + DV+ C +NPTG +R+Q +++ + I D AY F ED + Y I Sbjct: 171 KDDVLLLHPCC-HNPTGVDLTREQWDTVLNVIQERELIPFMDIAYQGFGEDMDSDA-YAI 228 Query: 270 PGAREVAIEV---SSFSKFAGFTGVRLG 294 A ++ + + +SFSK G R+G Sbjct: 229 RKAVDMGLPLFVSNSFSKNLSLYGERVG 256 >4H51-A nrPDB Length = 420 Score = 30.4 bits (67), Expect = 1.8, Method: Compositional matrix adjust. Identities = 26/93 (27%), Positives = 35/93 (37%), Gaps = 4/93 (4%) Query: 206 DLAMTPRTDV-IFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPR 264 D+ P V I +NPTG S++Q +++ + FDSAY + Sbjct: 183 DILAAPDGSVFILHQCAHNPTGVDPSQEQWNEIASLMLAKHHQVFFDSAYQGYASGSLDT 242 Query: 265 SIYEIPGAREVAIEV---SSFSKFAGFTGVRLG 294 Y IEV SFSK G R G Sbjct: 243 DAYAARLFARRGIEVLLAQSFSKNMGLYSERAG 275 >4WD2-A nrPDB Length = 408 Score = 30.0 bits (66), Expect = 1.9, Method: Compositional matrix adjust. Identities = 23/89 (25%), Positives = 37/89 (41%), Gaps = 2/89 (2%) Query: 208 AMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIE--DGSPRS 265 A+ R+ V+ +NPTG Q +L+D + + D AY F D + Sbjct: 176 ALPARSIVLLHACCHNPTGVDLDEGQWEKLIDVIEARELLPFVDMAYQGFGAGLDADAFA 235 Query: 266 IYEIPGAREVAIEVSSFSKFAGFTGVRLG 294 + E+ + +SFSK G R+G Sbjct: 236 VRELARRGVPTLVANSFSKNFSLYGERVG 264 >1GG0-A nrPDB Length = 284 Score = 30.0 bits (66), Expect = 2.5, Method: Compositional matrix adjust. Identities = 30/118 (25%), Positives = 49/118 (41%), Gaps = 23/118 (19%) Query: 100 STVEGYRGYGLEQGNKT---LRKAIAETFYRDLHVKSNEVFVSD-----------GAQSD 145 S++ YRG GLE+G K L++ D+H S V+D Q+D Sbjct: 64 SSIHSYRGPGLEEGMKIFQELKQTFGVKIITDVHEPSQAQPVADVVDVIQLPAFLARQTD 123 Query: 146 ISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSF 203 + ++ + + I V+ P F V GQ G+ +K K+ N + C +F Sbjct: 124 L--VEAMAKTGAVINVKKPQF-------VSPGQMGNIVDKFKEGGNEKVILCDRGANF 172 >1FOK-A nrPDB Length = 576 Score = 29.3 bits (64), Expect = 3.9, Method: Compositional matrix adjust. Identities = 22/53 (41%), Positives = 29/53 (54%), Gaps = 5/53 (9%) Query: 282 FSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIV-TTSFNGASN--IAQA 331 F K G+ G LG S PD +Y+ G PI D+ IV T +++G N I QA Sbjct: 429 FMKVYGYRGKHLGGSRKPDGAIYTVGSPI--DYGVIVDTKAYSGGYNLPIGQA 479 >3RQ1-A nrPDB Length = 418 Score = 28.9 bits (63), Expect = 4.4, Method: Compositional matrix adjust. Identities = 20/56 (35%), Positives = 26/56 (46%), Gaps = 7/56 (12%) Query: 206 DLAMTPRTDVIFFCSP-NNPTGYVASRKQLHQLVDFAKT------NGSIIIFDSAY 254 +LA V+ F +P NNPTGY K +++F K N II D AY Sbjct: 173 ELAAKQTNVVVIFNTPGNNPTGYSIEDKDWDSILNFLKDLVAIGRNNVIIGIDVAY 228 >1H0O-A nrPDB Length = 390 Score = 28.9 bits (63), Expect = 4.9, Method: Compositional matrix adjust. Identities = 21/70 (30%), Positives = 34/70 (48%), Gaps = 9/70 (12%) Query: 137 FVSDGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMP 196 FV+D RL L LG N V++P ++++ + G+T F ++ +YQ + M Sbjct: 327 FVAD-------RLMLELGFNKIFRVENPF--DFMENISLEGKTNFFEKRVGEYQRMGVMS 377 Query: 197 CGPNNSFFPD 206 NSF D Sbjct: 378 NSTENSFTLD 387 >3MKJ-A nrPDB Length = 398 Score = 28.9 bits (63), Expect = 5.0, Method: Compositional matrix adjust. Identities = 13/47 (27%), Positives = 24/47 (51%), Gaps = 3/47 (6%) Query: 208 AMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAY 254 AM P T V++ +P NPT S + + A G++++ D+ + Sbjct: 145 AMRPETKVVYIETPANPT---LSLVDIETVAGIAHQQGALLVVDNTF 188 >3STG-A nrPDB Length = 268 Score = 28.9 bits (63), Expect = 5.1, Method: Compositional matrix adjust. Identities = 13/31 (41%), Positives = 18/31 (58%) Query: 93 SNFAHGLSTVEGYRGYGLEQGNKTLRKAIAE 123 ++F S++ YRG GLE+G K K AE Sbjct: 53 ASFDKPRSSIHSYRGVGLEEGLKIFEKVKAE 83 >4BUC-A nrPDB Length = 450 Score = 28.1 bits (61), Expect = 7.6, Method: Compositional matrix adjust. Identities = 14/45 (31%), Positives = 24/45 (53%) Query: 136 VFVSDGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTG 180 V+VS G + D S ++LL V ++ + F +D ++G TG Sbjct: 85 VYVSPGIKPDTSMIELLSSRGVKLSTELQFFLDNVDPKKVVGITG 129 >2A21-A nrPDB Length = 267 Score = 27.7 bits (60), Expect = 9.7, Method: Compositional matrix adjust. Identities = 12/24 (50%), Positives = 16/24 (66%) Query: 100 STVEGYRGYGLEQGNKTLRKAIAE 123 S++ +RG+GLE G K LRK E Sbjct: 50 SSIHSFRGHGLEYGVKALRKVKEE 73 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4FL0-A nrPDB 610 e-175 3EI8-A nrPDB 451 e-127 3QGU-A nrPDB 444 e-125 3ASB-A nrPDB 381 e-106 1GDE-A nrPDB 350 7e-97 1O4S-A nrPDB 336 1e-92 1GC4-A nrPDB 335 2e-92 1J32-A nrPDB 335 2e-92 6F77-B nrPDB 326 1e-89 2X5D-A nrPDB 326 1e-89 2Z61-A nrPDB 326 1e-89 1XI9-A nrPDB 314 6e-86 5WMH-A nrPDB 313 9e-86 6F35-A nrPDB 312 3e-85 4MY5-A nrPDB 310 9e-85 5YHV-A nrPDB 290 8e-79 3H14-A nrPDB 280 6e-76 2O1B-A nrPDB 280 7e-76 1U08-A nrPDB 277 1e-74 2ZJG-A nrPDB 268 3e-72 1V2E-A nrPDB 268 5e-72 3DYD-A nrPDB 265 3e-71 4WP0-A nrPDB 263 8e-71 3FVS-A nrPDB 263 8e-71 3PDX-A nrPDB 260 7e-70 3JTX-A nrPDB 255 2e-68 3ELE-A nrPDB 252 2e-67 4DQ6-A nrPDB 248 3e-66 1BW0-A nrPDB 238 4e-63 4CVQ-A nrPDB 233 9e-62 3AV7-A nrPDB 232 2e-61 3OP7-A nrPDB 229 2e-60 1YIY-A nrPDB 228 6e-60 4IX8-A nrPDB 227 7e-60 3B46-A nrPDB 226 2e-59 2O0R-A nrPDB 224 6e-59 2DOU-A nrPDB 224 7e-59 3T32-A nrPDB 218 6e-57 3EZS-A nrPDB 217 8e-57 3FDB-A nrPDB 213 1e-55 3B1C-A nrPDB 212 3e-55 3DZZ-A nrPDB 206 2e-53 2ZYJ-A nrPDB 202 3e-52 1M4N-A nrPDB 199 2e-51 2HOR-A nrPDB 189 2e-48 4M2J-A nrPDB 181 8e-46 4R2N-A nrPDB 151 7e-37 1UU1-A nrPDB 148 5e-36 1IJI-A nrPDB 146 1e-35 3FFH-A nrPDB 146 3e-35 3CQ5-A nrPDB 141 8e-34 3FKD-A nrPDB 137 1e-32 1LC8-A nrPDB 135 4e-32 4RAE-A nrPDB 135 5e-32 5DJ3-A nrPDB 134 7e-32 3GET-A nrPDB 132 3e-31 3LY1-A nrPDB 130 1e-30 3FTB-A nrPDB 130 2e-30 3P1T-A nrPDB 123 2e-28 6C3C-A nrPDB 100 2e-21 1YAA-A nrPDB 86 2e-17 Sequences not found previously or not previously below threshold: 1X0M-A nrPDB 231 7e-61 2GB3-A nrPDB 209 2e-54 1WST-A nrPDB 204 6e-53 2ZC0-A nrPDB 197 8e-51 5Z0Q-C nrPDB 186 1e-47 3L8A-A nrPDB 182 3e-46 1IAY-A nrPDB 182 4e-46 1VP4-A nrPDB 178 6e-45 1C7O-A nrPDB 163 1e-40 1D2F-A nrPDB 157 9e-39 4GDY-A nrPDB 147 6e-36 3TCM-A nrPDB 141 9e-34 3NRA-A nrPDB 137 1e-32 3IHJ-A nrPDB 136 2e-32 3HDO-A nrPDB 132 3e-31 3IF2-A nrPDB 125 4e-29 6HNB-A nrPDB 125 5e-29 3G7Q-A nrPDB 121 9e-28 6HNV-A nrPDB 117 1e-26 4JE5-A nrPDB 117 1e-26 2ZY3-A nrPDB 113 2e-25 3EUC-A nrPDB 112 2e-25 3FDD-A nrPDB 110 2e-24 2ZY2-A nrPDB 107 9e-24 3G0T-A nrPDB 106 2e-23 4EMY-A nrPDB 104 6e-23 3F6T-A nrPDB 103 2e-22 3RQ1-A nrPDB 102 4e-22 5X03-B nrPDB 100 9e-22 4N0B-A nrPDB 100 1e-21 4F5M-A nrPDB 98 1e-20 1AY8-A nrPDB 97 2e-20 3FSL-A nrPDB 96 4e-20 3BWN-A nrPDB 95 7e-20 4WD2-A nrPDB 94 1e-19 4WBT-A nrPDB 92 5e-19 2X5F-A nrPDB 91 1e-18 3PD6-B nrPDB 88 7e-18 4RKC-A nrPDB 86 3e-17 4W5K-A nrPDB 85 5e-17 6EZL-A nrPDB 85 6e-17 3II0-A nrPDB 83 2e-16 1TAR-A nrPDB 83 3e-16 2CST-A nrPDB 81 9e-16 5IWQ-A nrPDB 81 1e-15 4H51-A nrPDB 79 5e-15 3MEB-A nrPDB 79 5e-15 4WB0-B nrPDB 77 2e-14 5TON-A nrPDB 76 3e-14 4EFF-A nrPDB 75 5e-14 2X8U-A nrPDB 67 1e-11 1M6S-A nrPDB 66 3e-11 4LW2-A nrPDB 65 7e-11 5C6U-A nrPDB 64 1e-10 3K7Y-A nrPDB 64 2e-10 3MKJ-A nrPDB 60 2e-09 6CJB-A nrPDB 59 5e-09 3VK2-A nrPDB 57 2e-08 3QI6-A nrPDB 57 2e-08 2C81-A nrPDB 55 8e-08 4W91-A nrPDB 55 8e-08 3TQX-A nrPDB 54 1e-07 6ONN-A nrPDB 54 2e-07 4PIW-A nrPDB 54 2e-07 4BMK-A nrPDB 54 2e-07 3WY7-A nrPDB 53 3e-07 3NYS-A nrPDB 52 4e-07 1IBJ-A nrPDB 52 6e-07 3BB8-A nrPDB 52 7e-07 4K2M-A nrPDB 52 8e-07 3DR4-A nrPDB 51 9e-07 5TSU-A nrPDB 51 1e-06 4L0O-H nrPDB 51 2e-06 4U1T-A nrPDB 49 4e-06 1CS1-A nrPDB 49 5e-06 2DR1-A nrPDB 49 6e-06 2OGE-A nrPDB 49 6e-06 2DKJ-A nrPDB 48 7e-06 3ECD-A nrPDB 48 8e-06 5K8B-A nrPDB 48 1e-05 3UWC-A nrPDB 47 1e-05 5JAY-A nrPDB 47 1e-05 4OC9-A nrPDB 47 1e-05 1E5F-A nrPDB 47 1e-05 5X5H-A nrPDB 47 2e-05 3WGB-A nrPDB 46 4e-05 1FC4-A nrPDB 46 5e-05 5W70-A nrPDB 45 6e-05 3AEO-A nrPDB 45 7e-05 4OTL-A nrPDB 45 7e-05 1N8P-A nrPDB 45 8e-05 2CB1-A nrPDB 44 2e-04 2GMS-A nrPDB 44 2e-04 4J5U-A nrPDB 44 2e-04 4IYO-A nrPDB 42 4e-04 6MRE-A nrPDB 42 5e-04 1SVV-A nrPDB 42 5e-04 2E7J-A nrPDB 42 8e-04 6C9E-A nrPDB 41 0.001 5VMB-A nrPDB 41 0.001 5W1B-A nrPDB 41 0.001 3NDN-A nrPDB 41 0.001 1WYV-B nrPDB 41 0.001 5I92-A nrPDB 40 0.002 6JEQ-A nrPDB 40 0.002 1B9H-A nrPDB 40 0.003 3N0L-A nrPDB 39 0.003 5LL2-A nrPDB 39 0.004 5WT2-A nrPDB 39 0.004 3RUY-A nrPDB 39 0.004 2EH6-A nrPDB 39 0.004 5IJG-A nrPDB 39 0.005 5WGB-A nrPDB 39 0.005 4KAM-A nrPDB 39 0.006 3G8M-A nrPDB 39 0.006 3GZD-A nrPDB 38 0.008 5U24-A nrPDB 38 0.008 1YJS-A nrPDB 38 0.009 3I5T-A nrPDB 37 0.012 5TXT-B nrPDB 37 0.013 4WXB-A nrPDB 37 0.018 3GBX-A nrPDB 37 0.020 3OKS-A nrPDB 37 0.024 1DJ9-A nrPDB 36 0.029 6CBN-A nrPDB 36 0.030 4PPM-A nrPDB 36 0.033 4ADC-A nrPDB 36 0.042 3MAF-B nrPDB 35 0.068 4GSA-A nrPDB 35 0.069 4OBV-D nrPDB 35 0.072 2JJG-A nrPDB 35 0.073 1VJO-A nrPDB 35 0.077 3N5M-A nrPDB 35 0.088 4UHN-A nrPDB 34 0.12 5VIU-A nrPDB 34 0.12 4JF0-A nrPDB 34 0.12 5KR3-A nrPDB 34 0.13 2BHU-A nrPDB 34 0.14 5KR5-A nrPDB 34 0.15 3I4J-A nrPDB 34 0.17 4P3M-A nrPDB 34 0.19 1SFF-A nrPDB 34 0.21 3RI6-A nrPDB 34 0.21 5LH9-A nrPDB 33 0.22 6GIO-D nrPDB 33 0.25 4E3Q-A nrPDB 33 0.29 3NNK-A nrPDB 33 0.33 4BQ0-A nrPDB 33 0.34 5EAV-A nrPDB 32 0.39 3A74-A nrPDB 32 0.62 4K5R-A nrPDB 32 0.62 2E8Y-A nrPDB 32 0.78 3DOD-A nrPDB 32 0.80 2FQ6-A nrPDB 31 0.92 5YKR-A nrPDB 31 1.2 5YZA-A nrPDB 30 1.6 3A1D-A nrPDB 30 1.6 1O69-A nrPDB 30 1.9 5CM6-A nrPDB 30 2.0 3O55-A nrPDB 30 2.0 3J09-A nrPDB 30 2.1 3J08-A nrPDB 30 2.2 5GKN-A nrPDB 30 2.3 2OCI-A nrPDB 30 2.5 5YSZ-A nrPDB 30 3.0 5VNX-A nrPDB 30 3.1 1EA9-C nrPDB 30 3.1 2CH1-A nrPDB 29 3.4 1CYG-A nrPDB 29 3.6 6FK4-A nrPDB 29 3.8 3RSY-A nrPDB 29 3.9 1ULZ-A nrPDB 29 3.9 3ROH-A nrPDB 29 4.3 2ZUK-A nrPDB 29 4.3 1EHA-A nrPDB 29 4.4 3HXT-A nrPDB 29 4.6 2Z9W-A nrPDB 29 4.9 2EJ2-A nrPDB 29 5.7 4YPJ-A nrPDB 29 6.4 1WA5-C nrPDB 29 6.6 3U9T-A nrPDB 29 6.9 5LBF-A nrPDB 28 8.7 >4FL0-A nrPDB Length = 456 Score = 610 bits (1574), Expect = e-175, Method: Composition-based stats. Identities = 456/456 (100%), Positives = 456/456 (100%) Query: 1 MVSLMFFSSASPLCSSPSKIPKASLDFEMKKLGGSTKLVRNVNLEKLKNNYLFPEINRRE 60 MVSLMFFSSASPLCSSPSKIPKASLDFEMKKLGGSTKLVRNVNLEKLKNNYLFPEINRRE Sbjct: 1 MVSLMFFSSASPLCSSPSKIPKASLDFEMKKLGGSTKLVRNVNLEKLKNNYLFPEINRRE 60 Query: 61 LEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKA 120 LEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKA Sbjct: 61 LEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKA 120 Query: 121 IAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTG 180 IAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTG Sbjct: 121 IAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTG 180 Query: 181 HFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDF 240 HFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDF Sbjct: 181 HFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDF 240 Query: 241 AKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPD 300 AKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPD Sbjct: 241 AKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPD 300 Query: 301 ELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILM 360 ELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILM Sbjct: 301 ELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILM 360 Query: 361 DTLVSLGLKVYGGVNAPYLWVHFKGSKSWDVFNEILENTHIITVPGSGFGPGGEEYLRIS 420 DTLVSLGLKVYGGVNAPYLWVHFKGSKSWDVFNEILENTHIITVPGSGFGPGGEEYLRIS Sbjct: 361 DTLVSLGLKVYGGVNAPYLWVHFKGSKSWDVFNEILENTHIITVPGSGFGPGGEEYLRIS 420 Query: 421 GFGRRDHIVEASKRLQNFFNTRTKHFTYLSSTSNTN 456 GFGRRDHIVEASKRLQNFFNTRTKHFTYLSSTSNTN Sbjct: 421 GFGRRDHIVEASKRLQNFFNTRTKHFTYLSSTSNTN 456 >3EI8-A nrPDB Length = 432 Score = 451 bits (1160), Expect = e-127, Method: Composition-based stats. Identities = 256/411 (62%), Positives = 321/411 (78%) Query: 30 KKLGGSTKLVRNVNLEKLKNNYLFPEINRRELEHIEKHPNVQLISLGTGDTTEPIPEQIT 89 +K+ TK+ RN N+ KL+ YLFPEI RR H+ K+P+ Q+ISLG GDTTEPIPE IT Sbjct: 16 EKIEYKTKVSRNSNMSKLQAGYLFPEIARRRSAHLLKYPDAQVISLGIGDTTEPIPEVIT 75 Query: 90 SHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRL 149 S M+ AH LST+EGY GYG EQG K LR AIA+TFY L + ++VFVSDGA+ DISRL Sbjct: 76 SAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDISRL 135 Query: 150 QLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAM 209 Q++ GSNVTIAVQDP++PAY+DSSVI+GQTG F+ +KY N+ YM C P N FFPDL+ Sbjct: 136 QVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLST 195 Query: 210 TPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEI 269 RTD+IFFCSPNNPTG A+R+QL QLV+FAK NGSII++DSAYA ++ D +PRSI+EI Sbjct: 196 VGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEI 255 Query: 270 PGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIA 329 PGA EVA+E +SFS +AGFTGVRLGW++IP +LLYS+GFP+ DF+RI+ T FNGASNI+ Sbjct: 256 PGAEEVAMETASFSNYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNIS 315 Query: 330 QAGGLACLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSW 389 QAG LACL+ GL+ + V +YKEN I++DT SLG VYGG NAPY+WVHF SW Sbjct: 316 QAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSW 375 Query: 390 DVFNEILENTHIITVPGSGFGPGGEEYLRISGFGRRDHIVEASKRLQNFFN 440 DVF EILE TH++T PGSGFGPGGE ++R+S FG R++I+EA +R + + Sbjct: 376 DVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQLYK 426 >3QGU-A nrPDB Length = 449 Score = 444 bits (1143), Expect = e-125, Method: Composition-based stats. Identities = 226/437 (51%), Positives = 308/437 (70%), Gaps = 3/437 (0%) Query: 8 SSASPLCSSPSKIPKASLDFEMKKLGGSTKLVRNVNLEKLKNNYLFPEINRRELEHIEKH 67 S+AS SS ++ + + G+ + RN N KL+ YLFPEI RR H EK+ Sbjct: 7 STASGARSSTRSRRMTAVVQAVAQRAGTIDVQRNENFGKLRAGYLFPEIARRRKAHQEKN 66 Query: 68 PNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYR 127 P+ ++ISLG GDTTEP+P+ I M+ A GL+T EGY GYG EQG LR+A+A TFY Sbjct: 67 PDAKIISLGIGDTTEPLPKYIADAMAKAAAGLATREGYSGYGAEQGQGALREAVASTFYG 126 Query: 128 DLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTK 187 ++E+F+SDG++ DI+R+Q++ GS T+AVQDP++P Y+D+SV++G TG + Sbjct: 127 HAGRAADEIFISDGSKCDIARIQMMFGSKPTVAVQDPSYPVYVDTSVMMGMTGDHNGTG- 185 Query: 188 KYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSI 247 + + YM C P+N FFPDL+ RTD+IFFCSPNNPTG A+R QL +LV+FA+ NGSI Sbjct: 186 -FDGIEYMVCNPDNHFFPDLSKAKRTDIIFFCSPNNPTGAAATRAQLTELVNFARKNGSI 244 Query: 248 IIFDSAYAAFIEDG-SPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSN 306 +++D+AYA +I + P++IYEIPGA EVAIE SFSK+AGFTGVRLGW+++P L Y+N Sbjct: 245 LVYDAAYALYISNPDCPKTIYEIPGADEVAIETCSFSKYAGFTGVRLGWTVVPKALKYAN 304 Query: 307 GFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILMDTLVSL 366 G P+ D++R++TT FNGASNI QAGGLACL GLKE+ ++ +YKEN +IL T + Sbjct: 305 GEPVHADWNRVMTTCFNGASNIVQAGGLACLQPEGLKEMNAMIKFYKENAQILKTTFTEM 364 Query: 367 GLKVYGGVNAPYLWVHFKGSKSWDVFNEILENTHIITVPGSGFGPGGEEYLRISGFGRRD 426 G VYGG +APY+WV F G SWDVF EILE +I+T PGSG+GP GE ++R S FG R+ Sbjct: 365 GFSVYGGDDAPYIWVGFPGKPSWDVFAEILERCNIVTTPGSGYGPAGEGFVRASAFGSRE 424 Query: 427 HIVEASKRLQNFFNTRT 443 +I+EA +R + + R Sbjct: 425 NILEAVRRFKEAYGKRN 441 >3ASB-A nrPDB Length = 400 Score = 381 bits (978), Expect = e-106, Method: Composition-based stats. Identities = 159/402 (39%), Positives = 238/402 (59%), Gaps = 18/402 (4%) Query: 38 LVRNVNLEKLKNNYLFPEINRRELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAH 97 + RN + L NYLF ++ +R + ++P +I+L GDTT+P+ + ++ Sbjct: 1 MKRNPHFVSLTKNYLFADLQKRVAQFRLENPQHTVINLSIGDTTQPLNASVAEAFASSIA 60 Query: 98 GLSTVEGYRGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNV 157 LS+ RGYG + G LR+ ++E FYR V + E+F+SDGA+ D+ RL G N Sbjct: 61 RLSSPTTCRGYGPDFGLPALRQKLSEDFYRGF-VDAKEIFISDGAKVDLFRLLSFFGPNQ 119 Query: 158 TIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIF 217 T+A+QDP++PAY+D + + G ++ +PC N+FFP+ D++ Sbjct: 120 TVAIQDPSYPAYLDIARLTGAK-----------EIIALPCLQENAFFPEFPEDTHIDILC 168 Query: 218 FCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGS-PRSIYEIPGAREVA 276 CSPNNPTG V ++ QL +V +A + +I+FD+AY+ FI D S P+SI+EIP AR A Sbjct: 169 LCSPNNPTGTVLNKDQLRAIVHYAIEHEILILFDAAYSTFISDPSLPKSIFEIPDARFCA 228 Query: 277 IEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLAC 336 IE++SFSK GF G+RLGW++IP EL Y++G +I D+ R ++T+FNGAS AQ G+A Sbjct: 229 IEINSFSKPLGFAGIRLGWTVIPQELTYADGHFVIQDWERFLSTTFNGASIPAQEAGVAG 288 Query: 337 LSSGGLKEIRSVNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHF--KGSKSWDVFNE 394 LS +YY+EN +L L++ G +V+GG +APYLWV D+F+ Sbjct: 289 LSILPQ---LEAIHYYRENSDLLRKALLATGFEVFGGEHAPYLWVKPTQANISDRDLFDF 345 Query: 395 ILENTHIITVPGSGFGPGGEEYLRISGFGRRDHIVEASKRLQ 436 L HI PG GFG G ++R S G+R+ I+ A +RLQ Sbjct: 346 FLREYHIAITPGIGFGRSGSGFVRFSSLGKREDILAACERLQ 387 >1GDE-A nrPDB Length = 389 Score = 350 bits (898), Expect = 7e-97, Method: Composition-based stats. Identities = 97/386 (25%), Positives = 150/386 (38%), Gaps = 38/386 (9%) Query: 70 VQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYRDL 129 +ISLG G+ P+ I + +G YG G LR+AIAE + Sbjct: 26 KDVISLGIGEPDFDTPQHIKEYAKEAL-----DKGLTHYGPNIGLLELREAIAEKLKKQN 80 Query: 130 HVKSN---EVFVSDGAQSD-ISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEK 185 ++++ E+ V GA + L L + + P F +Y + ++ G Sbjct: 81 GIEADPKTEIMVLLGANQAFLMGLSAFLKDGEEVLIPTPAFVSYAPAVILAGGKP----- 135 Query: 186 TKKYQNVVYMPCGPNNSFFPDLA-----MTPRTDVIFFCSPNNPTGYVASRKQLHQLVDF 240 V +P + F ++ +T +T + SP NPTG V ++K L ++ DF Sbjct: 136 -------VEVPTYEEDEFRLNVDELKKYVTDKTRALIINSPCNPTGAVLTKKDLEEIADF 188 Query: 241 AKTNGSIIIFDSAYAAFIEDG-SPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIP 299 + I+I D Y FI D SI + G E I V+ FSK TG RLG+ P Sbjct: 189 VVEHDLIVISDEVYEHFIYDDARHYSIASLDGMFERTITVNGFSKTFAMTGWRLGFVAAP 248 Query: 300 DELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACL-SSGGLKEIRSVNNYYKENRKI 358 II + + Q L K + + Y RK+ Sbjct: 249 SW--------IIERMVKFQMYNATCPVTFIQYAAAKALKDERSWKAVEEMRKEYDRRRKL 300 Query: 359 LMDTLVSLGLKVYGGVNAPYLWVHFK--GSKSWDVFNEILENTHIITVPGSGFGPGGEEY 416 + L +GL A Y++ + G S +L+ + VPGS FG GE Y Sbjct: 301 VWKRLNEMGLPTVKPKGAFYIFPRIRDTGLTSKKFSELMLKEARVAVVPGSAFGKAGEGY 360 Query: 417 LRISGFGRRDHIVEASKRLQNFFNTR 442 +RIS + + EA R++ R Sbjct: 361 VRISYATAYEKLEEAMDRMERVLKER 386 >1O4S-A nrPDB Length = 389 Score = 336 bits (862), Expect = 1e-92, Method: Composition-based stats. Identities = 89/391 (22%), Positives = 162/391 (41%), Gaps = 32/391 (8%) Query: 55 EINRRELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGN 114 E++ + I+K +I+L G+ P PE + F +G Y +G Sbjct: 28 ELDAKAKALIKK--GEDVINLTAGEPDFPTPEPVVEEAVRFLQ-----KGEVKYTDPRGI 80 Query: 115 KTLRKAIAETFYRDL--HVKSNEVFVSDGAQSDI-SRLQLLLGSNVTIAVQDPTFPAYID 171 LR+ IA+ + ++V V++GA+ + + LL + V P + +YI Sbjct: 81 YELREGIAKRIGERYKKDISPDQVVVTNGAKQALFNAFMALLDPGDEVIVFSPVWVSYIP 140 Query: 172 SSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASR 231 ++ G T + E + + + +T + SPNNPTG V R Sbjct: 141 QIILAGGTVNVVETFMSKNFQPSLEEV-------EGLLVGKTKAVLINSPNNPTGVVYRR 193 Query: 232 KQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGV 291 + L LV AK II D Y + + SI ++ + + ++ FSK TG Sbjct: 194 EFLEGLVRLAKKRNFYIISDEVYDSLVYTDEFTSILDVSEGFDRIVYINGFSKSHSMTGW 253 Query: 292 RLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNY 351 R+G+ I + + +I + + + + +AQ L L +++ Sbjct: 254 RVGYLISSE--------KVATAVSKIQSHTTSCINTVAQYAALKALEVDNSYMVQT---- 301 Query: 352 YKENRKILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSWDVFNEILENTHIITVPGSGFGP 411 +KE + +++ L +G+K A YL+ +G +LE + VPGS F Sbjct: 302 FKERKNFVVERLKKMGVKFVEPEGAFYLFFKVRG-DDVKFCERLLEEKKVALVPGSAFLK 360 Query: 412 GGEEYLRISGFGRRDHIVEASKRLQNFFNTR 442 G ++R+S + + EA R+++F N+R Sbjct: 361 PG--FVRLSFATSIERLTEALDRIEDFLNSR 389 >1GC4-A nrPDB Length = 385 Score = 335 bits (859), Expect = 2e-92, Method: Composition-based stats. Identities = 92/407 (22%), Positives = 154/407 (37%), Gaps = 40/407 (9%) Query: 46 KLKNNYLFPEINRRELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGY 105 +++ + + V L++L G+ PE + +G Sbjct: 7 RVQAMKPDAVVAVNAKALELRRQGVDLVALTAGEPDFDTPEHVKEAARRALA-----QGK 61 Query: 106 RGYGLEQGNKTLRKAIAETFYRDLH--VKSNEVFVS-DGAQSDISRLQLLLGSNVTIAVQ 162 Y G LR+A+AE F R+ V E V+ G+Q+ + Q +L + V Sbjct: 62 TKYAPPAGIPELREALAEKFRRENGLSVTPEETIVTVGGSQALFNLFQAILDPGDEVIVL 121 Query: 163 DPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPD-----LAMTPRTDVIF 217 P + +Y + G VV + P F PD A+TPRT + Sbjct: 122 SPYWVSYPEMVRFAGGV------------VVEVETLPEEGFVPDPERVRRAITPRTKALV 169 Query: 218 FCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAI 277 SPNNPTG V ++ L L A + ++ D Y + +G S + A E + Sbjct: 170 VNSPNNPTGAVYPKEVLEALARLAVEHDFYLVSDEIYEHLLYEGEHFSPGRV--APEHTL 227 Query: 278 EVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACL 337 V+ +K TG R+G++ P E +I + S IAQ L L Sbjct: 228 TVNGAAKAFAMTGWRIGYACGPKE--------VIKAMASVSRQSTTSPDTIAQWATLEAL 279 Query: 338 SSGGLK--EIRSVNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSWDV-FNE 394 ++ + Y+ R +L++ L +LGLK A Y+ + +V E Sbjct: 280 TNQEASRAFVEMAREAYRRRRDLLLEGLTALGLKAVRPSGAFYVLMDTSPIAPDEVRAAE 339 Query: 395 ILENTHIITVPGSGFGPGGEEYLRISGFGRRDHIVEASKRLQNFFNT 441 L + VPG+ F G ++R+S +++ +A +R Sbjct: 340 RLLEAGVAVVPGTDFAAFG--HVRLSYATSEENLRKALERFARVLGR 384 >1J32-A nrPDB Length = 388 Score = 335 bits (859), Expect = 2e-92, Method: Composition-based stats. Identities = 88/389 (22%), Positives = 159/389 (40%), Gaps = 31/389 (7%) Query: 60 ELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRK 119 K + + S G+ P+ I +G YG G LR+ Sbjct: 20 AKAKAMKAEGIDVCSFSAGEPDFNTPKHIVEAAKAALE-----QGKTRYGPAAGEPRLRE 74 Query: 120 AIAETFYRDLHV--KSNEVFVSDGAQSDISRLQ-LLLGSNVTIAVQDPTFPAYIDSSVII 176 AIA+ RD + ++ + V++G + I L ++ + + P + +Y + + Sbjct: 75 AIAQKLQRDNGLCYGADNILVTNGGKQSIFNLMLAMIEPGDEVIIPAPFWVSYPEMVKLA 134 Query: 177 GQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQ 236 T T + Q V A+TP+T ++ F +P+NPTG V + ++ Sbjct: 135 EGTPVILPTTVETQFKVSPEQIRQ-------AITPKTKLLVFNTPSNPTGMVYTPDEVRA 187 Query: 237 LVDFAKTNGSIIIFDSAYAAFIEDG-SPRSI-YEIPGAREVAIEVSSFSKFAGFTGVRLG 294 + A G ++ D Y + D SI P A E ++ S F+K TG R+G Sbjct: 188 IAQVAVEAGLWVLSDEIYEKILYDDAQHLSIGAASPEAYERSVVCSGFAKTYAMTGWRVG 247 Query: 295 WSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKE 354 + P P++ +I S + AQ G +A + ++ + + E Sbjct: 248 FLAGP--------VPLVKAATKIQGHSTSNVCTFAQYGAIAAYENS-QDCVQEMLAAFAE 298 Query: 355 NRKILMDTLVSL-GLKVYGGVNAPYLWVHFK--GSKSWDVFNEILENTHIITVPGSGFGP 411 R+ ++D L ++ GL+ A Y++ G S D +E+L+ + TVPG+ FG Sbjct: 299 RRRYMLDALNAMPGLECPKPDGAFYMFPSIAKTGRSSLDFCSELLDQHQVATVPGAAFGA 358 Query: 412 GGEEYLRISGFGRRDHIVEASKRLQNFFN 440 ++ +R+S D I +RL+ F + Sbjct: 359 --DDCIRLSYATDLDTIKRGMERLEKFLH 385 >6F77-B nrPDB Length = 400 Score = 326 bits (836), Expect = 1e-89, Method: Composition-based stats. Identities = 92/414 (22%), Positives = 155/414 (37%), Gaps = 45/414 (10%) Query: 44 LEKLKNNYLFPEINRRELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVE 103 L ++K + I + K +I LG G+ P+ I + Sbjct: 8 LSRVKPS---ATIAVSQKARELKAKGRDVIGLGAGEPDFDTPDNIKKAAIDA-----IDR 59 Query: 104 GYRGYGLEQGNKTLRKAIAETFYRDLHVK---SNEVFVSDGAQSDISRLQLLLGSNVTIA 160 G Y G LR+AIA+ F R+ ++ + + + G Q + L + Sbjct: 60 GETKYTPVSGIPELREAIAKKFKRENNLDYTAAQTIVGTGGKQILFNAFMATLNPGDEVV 119 Query: 161 VQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCS 220 + P + +Y + + G T F ++ + + D A+TP+T F S Sbjct: 120 IPAPYWVSYPEMVALCGGTPVFVPTRQENNFKL-------KAEDLDRAITPKTKWFVFNS 172 Query: 221 PNNPTGYVASRKQLHQLVDFAKTNGSIIIF-DSAYAAFIE-DGSPRSIYEI-PGAREVAI 277 P+NP+G S ++L L D + + + D Y D + E+ PG E + Sbjct: 173 PSNPSGAAYSHEELKALTDVLMKHPHVWVLTDDMYEHLTYGDFRFATPVEVEPGLYERTL 232 Query: 278 EVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACL 337 ++ SK TG R+G++ P L I I +GA++IAQ + L Sbjct: 233 TMNGVSKAYAMTGWRIGYAAGPLHL--------IKAMDMIQGQQTSGAASIAQWAAVEAL 284 Query: 338 SSGGLKEIRSVNNYYKENRKILMDTLVSL-GLKVYGGVNAPYLWVHFKG----------- 385 + G I ++ R +++ L G+ A Y++ G Sbjct: 285 N-GPQDFIGRNKEIFQGRRDLVVSMLNQAKGISCPTPEGAFYVYPSCAGLIGKTAPSGKV 343 Query: 386 -SKSWDVFNEILENTHIITVPGSGFGPGGEEYLRISGFGRRDHIVEASKRLQNF 438 D +E+LE + V GS FG G RIS + EA +R+Q F Sbjct: 344 IETDEDFVSELLETEGVAVVHGSAFGLGPN--FRISYATSEALLEEACRRIQRF 395 >2X5D-A nrPDB Length = 412 Score = 326 bits (835), Expect = 1e-89, Method: Composition-based stats. Identities = 95/396 (23%), Positives = 166/396 (41%), Gaps = 39/396 (9%) Query: 60 ELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRK 119 EL+ + +I L G+ P P I + A E GY +G LR+ Sbjct: 27 ELKMAARRRGEDIIDLSMGNPDGPTPPHIVEKLCTVAQR----EDTHGYSTSRGIPRLRR 82 Query: 120 AIAETFYRDLHV---KSNEVFVSDGAQSDISRLQ-LLLGSNVTIAVQDPTFPAYIDSSVI 175 AI+ + V +E V+ G++ ++ L L TI V +P++P +I +VI Sbjct: 83 AISHWYRDRYDVQIDPESEAIVTIGSKEGLAHLMLATLDHGDTILVPNPSYPIHIYGAVI 142 Query: 176 IGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMT-----PRTDVIFFCSPNNPTGYVAS 230 G V +P P FF +L P+ ++ P+NPT Sbjct: 143 AGA------------QVRSVPLVPGIDFFNELERAIRESIPKPRMMILGFPSNPTAQCVE 190 Query: 231 RKQLHQLVDFAKTNGSIIIFDSAYAAFIEDG-SPRSIYEIPGAREVAIEVSSFSKFAGFT 289 ++V AK +++ D AYA + DG SI ++PGA+++A+E + SK Sbjct: 191 LDFFERVVALAKQYDVMVVHDLAYADIVYDGWKAPSIMQVPGAKDIAVEFFTLSKSYNMA 250 Query: 290 GVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVN 349 G R+G+ + EL ++ RI + G Q +A L G + +R + Sbjct: 251 GWRIGFMVGNPEL--------VSALARIKSYHDYGTFTPLQVAAIAAL-EGDQQCVRDIA 301 Query: 350 NYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFK----GSKSWDVFNEILENTHIITVP 405 Y++ R +L+ L G V + Y+W S + ++L++ + P Sbjct: 302 RQYQQRRDVLVKGLREAGWMVENPKASMYVWAKIPEPYAHLGSLEFAKKLLQDAKVSVSP 361 Query: 406 GSGFGPGGEEYLRISGFGRRDHIVEASKRLQNFFNT 441 G GFG G++++R + RD + +A + ++ F Sbjct: 362 GIGFGDYGDDHVRFALIENRDRLRQAVRGIKAMFRA 397 >2Z61-A nrPDB Length = 370 Score = 326 bits (835), Expect = 1e-89, Method: Composition-based stats. Identities = 88/392 (22%), Positives = 157/392 (40%), Gaps = 36/392 (9%) Query: 53 FPEINRRELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQ 112 F ++ L + ++I L G+ P+ I EG Y + Sbjct: 12 FEVMDILALAQKLESEGKKVIHLEIGEPDFNTPKPIVDEGIKSLK-----EGKTHYTDSR 66 Query: 113 GNKTLRKAIAETFYRDL--HVKSNEVFVSDGAQ-SDISRLQLLLGSNVTIAVQDPTFPAY 169 G LR+ I+E + + + + ++ G+ L ++ + +Q+P +P Y Sbjct: 67 GILELREKISELYKDKYKADIIPDNIIITGGSSLGLFFALSSIIDDGDEVLIQNPCYPCY 126 Query: 170 IDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVA 229 + +G F + T + + A++ +T I SP+NP G V Sbjct: 127 KNFIRFLGAKPVFCDFTVES---------------LEEALSDKTKAIIINSPSNPLGEVI 171 Query: 230 SRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFT 289 R+ + +FA N II D Y + +G S E E I ++ FSK T Sbjct: 172 DRE----IYEFAYENIPYIISDEIYNGLVYEGKCYSAIEFDENLEKTILINGFSKLYAMT 227 Query: 290 GVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVN 349 G R+G+ I DE II ++ F A I+Q L +EI S+ Sbjct: 228 GWRIGYVISNDE--------IIEAILKLQQNLFISAPTISQYAALKAFEKETEREINSMI 279 Query: 350 NYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSWDVFNEILENTHIITVPGSGF 409 + R++++ + G +V + A Y++ + G + ++L+ + PG GF Sbjct: 280 KEFDRRRRLVLKYVKDFGWEVNNPIGAYYVFPNI-GEDGREFAYKLLKEKFVALTPGIGF 338 Query: 410 GPGGEEYLRISGFGRRDHIVEASKRLQNFFNT 441 G G+ Y+RIS ++I E +R++ F N Sbjct: 339 GSKGKNYIRISYANSYENIKEGLERIKEFLNK 370 >1XI9-A nrPDB Length = 406 Score = 314 bits (804), Expect = 6e-86, Method: Composition-based stats. Identities = 97/406 (23%), Positives = 150/406 (36%), Gaps = 43/406 (10%) Query: 56 INRRELEHIEKHPNVQLISLGTGDT---TEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQ 112 + RELE +++I L GD PE + + + EG+ YG + Sbjct: 28 LPARELEK----KGIKVIRLNIGDPVKFDFQPPEHMKEA-----YCKAIKEGHNYYGDSE 78 Query: 113 GNKTLRKAIAETFYRDLHVK--SNEVFVSDGAQSDISRLQ-LLLGSNVTIAVQDPTFPAY 169 G LRKAI E R V ++V V+ + + LL I V P++P Y Sbjct: 79 GLPELRKAIVEREKRKNGVDITPDDVRVTAAVTEALQLIFGALLDPGDEILVPGPSYPPY 138 Query: 170 IDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDL-----AMTPRTDVIFFCSPNNP 224 G V + PD+ +T RT I +PNNP Sbjct: 139 TGLVKFYGGKP------------VEYRTIEEEDWQPDIDDIRKKITDRTKAIAVINPNNP 186 Query: 225 TGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSK 284 TG + +K L ++++ A +I D Y +G S + I ++ SK Sbjct: 187 TGALYDKKTLEEILNIAGEYEIPVISDEIYDLMTYEGEHISPGSLTKDV-PVIVMNGLSK 245 Query: 285 FAGFTGVRLGWSIIPD-ELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLK 343 TG RLG+ D E S I+ RI + AQ +A L +G + Sbjct: 246 VYFATGWRLGYMYFVDPENKLSEVREAIDRLARIRL----CPNTPAQFAAIAGL-TGPMD 300 Query: 344 EIRSVNNYYKENRKILMDTLVSL-GLKVYGGVNAPYLWVHF---KGSKSWDVFNEILENT 399 ++ KE R + L + G+ A Y++ + ++L N Sbjct: 301 YLKEYMKKLKERRDYIYKRLNEIPGISTTKPQGAFYIFPKIEVGPWKNDKEFVLDVLHNA 360 Query: 400 HIITVPGSGFGPGGEEYLRISGFGRRDHIVEASKRLQNFFNTRTKH 445 H++ V GSGFG G + R + + EA R + F R K Sbjct: 361 HVLFVHGSGFGEYGAGHFRAVFLPPIEILEEAMDRFEKFMKERLKE 406 >5WMH-A nrPDB Length = 475 Score = 313 bits (802), Expect = 9e-86, Method: Composition-based stats. Identities = 86/435 (19%), Positives = 171/435 (39%), Gaps = 49/435 (11%) Query: 28 EMKKLGGSTKLVRNVNLEKLKNN--YLFPEINRRELEHIEKHPNVQLISLGTGDTTEPIP 85 + + L S + + ++ LK + + ++ ++ V +I L G+ P Sbjct: 60 DAETLSSSVDMSLSPRVQSLKPSKTMVITDLAATLVQS-----GVPVIRLAAGEPDFDTP 114 Query: 86 EQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYRDLHV--KSNEVFVSDGAQ 143 + + N EG+ Y L G LR+AI + + +++ VS+GA+ Sbjct: 115 KVVAEAGINA-----IREGFTRYTLNAGITELREAICRKLKEENGLSYAPDQILVSNGAK 169 Query: 144 SDIS-RLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNS 202 + + + + + P + +Y + + + T ++ + Sbjct: 170 QSLLQAVLAVCSPGDEVIIPAPYWVSYTEQARLADATPVVIPTKISNNFLL-------DP 222 Query: 203 FFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNG-SIIIFDSAYAAFIE-D 260 + +T ++ ++ CSP+NPTG V + L ++ + +++ D Y I Sbjct: 223 KDLESKLTEKSRLLILCSPSNPTGSVYPKSLLEEIARIIAKHPRLLVLSDEIYEHIIYAP 282 Query: 261 GSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTT 320 + S +P E + V+ FSK TG RLG+ P I+ ++ Sbjct: 283 ATHTSFASLPDMYERTLTVNGFSKAFAMTGWRLGYLAGPKH--------IVAACSKLQGQ 334 Query: 321 SFNGASNIAQAGGLACLSSG--GLKEIRSVNNYYKENRKILMDTLVSL-GLKVYGGVNAP 377 +GAS+IAQ G+A L G G + + + Y+E R L+ +L + G+K+ A Sbjct: 335 VSSGASSIAQKAGVAALGLGKAGGETVAEMVKAYRERRDFLVKSLGDIKGVKISEPQGAF 394 Query: 378 YLWVHFKGSKSWD------------VFNEILENTHIITVPGSGFGPGGEEYLRISGFGRR 425 YL++ F + + L+ + VPG FG + +RIS Sbjct: 395 YLFIDFSAYYGSEAEGFGLINDSSSLALYFLDKFQVAMVPGDAFGD--DSCIRISYATSL 452 Query: 426 DHIVEASKRLQNFFN 440 D + A ++++ Sbjct: 453 DVLQAAVEKIRKALE 467 >6F35-A nrPDB Length = 410 Score = 312 bits (798), Expect = 3e-85, Method: Composition-based stats. Identities = 88/400 (22%), Positives = 155/400 (38%), Gaps = 44/400 (11%) Query: 55 EINRRELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGN 114 +I R K +I LG G+ PE + S+ H G Y G Sbjct: 28 KIGARAAAM--KREGKPVIILGAGEPDFDTPEHVKQAASDAIHR-----GETKYTALDGT 80 Query: 115 KTLRKAIAETFYRDLHV--KSNEVFVSDGAQS-DISRLQLLLGSNVTIAVQDPTFPAYID 171 L+KAI E F R+ + + +E+ V+ GA+ + + L + + P + +Y D Sbjct: 81 PELKKAIREKFQRENGLAYELDEITVATGAKQILFNAMMASLDPGDEVIIPTPYWTSYSD 140 Query: 172 SSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASR 231 I + + + A+TPRT + SP+NP+G S Sbjct: 141 IVHICEGKPVLIACDASSGFRL-------TAEKLEAAITPRTRWVLLNSPSNPSGAAYSA 193 Query: 232 KQLHQLVDFAKTNGS-IIIFDSAYAAFIEDG-SPRSIYEI-PGAREVAIEVSSFSKFAGF 288 L++ + ++ D Y + DG + ++ PG + + V+ SK Sbjct: 194 ADYRPLLEVLLRHPHVWLLVDDMYEHIVYDGFRFVTPAQLEPGLKNRTLTVNGVSKAYAM 253 Query: 289 TGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSV 348 TG R+G++ P EL I + + + + S+I+QA + L+ G ++ Sbjct: 254 TGWRIGYAGGPREL--------IKAMAVVQSQATSCPSSISQAASVVALN-GPQDFLKER 304 Query: 349 NNYYKENRKILMDTLVSL-GLKVYGGVNAPYLWVHFKG------------SKSWDVFNEI 395 ++ R ++++ L ++ GL A Y + G D + Sbjct: 305 TESFQRRRDLVVNGLNAIDGLDCRVPEGAFYTFSGCAGVLGKVTPSGKRIKTDTDFCAYL 364 Query: 396 LENTHIITVPGSGFGPGGEEYLRISGFGRRDHIVEASKRL 435 LE+ H+ VPGS FG + RIS + EA +R+ Sbjct: 365 LEDAHVAVVPGSAFGL--SPFFRISYATSEAELKEALERI 402 >4MY5-A nrPDB Length = 393 Score = 310 bits (793), Expect = 9e-85, Method: Composition-based stats. Identities = 98/419 (23%), Positives = 155/419 (36%), Gaps = 38/419 (9%) Query: 34 GSTKLVR--NVNLEKLKNNYLFPEINRRELEHIEKHPNVQLISLGTGDTTEPIPEQITSH 91 G L + N NL K++ + + R+ + I P+V + L G+ P+ I Sbjct: 1 GPMDLSKRFNKNLNKIEVSMI-----RQFDQSISDIPDV--LKLTLGEPDFATPKHIKEA 53 Query: 92 MSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYRDLHV---KSNEVFVSDGAQSDISR 148 Y G LR+A + H+ NE+ V+ GA +S Sbjct: 54 AKRAIDA-----DESHYTGMAGLLALRQAASAFVKEKYHLTYNPDNEILVTIGATEALSA 108 Query: 149 -LQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDL 207 L +L + + P +P Y ++G E + + V P + + Sbjct: 109 SLTAILEPGDKVLLPAPAYPGYEPVVNLVGAE--VVEIDTRSNDFVLTPEMLEEAILKE- 165 Query: 208 AMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDG-SPRSI 266 + P NPTG SR+Q+ L + K +I D YA G S SI Sbjct: 166 --GEALKAVILNYPTNPTGVTYSRQQIKNLAEVLKKYPIFVISDEVYAELTYTGESHVSI 223 Query: 267 YEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGAS 326 E + I +S SK TG RLG P L +I +VT A+ Sbjct: 224 AEYLP--DQTILISGLSKSHAMTGWRLGLIFAPAVLTAQ----LIKSHQYLVT----AAT 273 Query: 327 NIAQAGGLACLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFK-- 384 Q + L++G + Y K R +++ + ++ K+ A Y++ Sbjct: 274 TSVQFAAIEALTNGKDDALPMKEEYIK-RRDYIIEKMEAMKFKIIKPDGAFYIFAKIPVA 332 Query: 385 -GSKSWDVFNEILENTHIITVPGSGFGPGGEEYLRISGFGRRDHIVEASKRLQNFFNTR 442 G S+ + + + +PG FG GE YLRIS + I EA KRL+ F Sbjct: 333 QGQDSFKFLQDFAKEKAVAFIPGVAFGKYGEGYLRISYAASMETIKEAMKRLKEFMEQY 391 >5YHV-A nrPDB Length = 394 Score = 290 bits (742), Expect = 8e-79, Method: Composition-based stats. Identities = 87/383 (22%), Positives = 152/383 (39%), Gaps = 37/383 (9%) Query: 71 QLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYR--D 128 L++L G + PE + + + H GY + G LR AIA + R Sbjct: 38 DLVNLSAGQPSAGAPEPVRAAAAAALHL-----NQLGYSVALGIPELRDAIAADYQRRHG 92 Query: 129 LHVKSNEVFVSDGAQSD-ISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTK 187 + V+ + V ++ G+ + + +A+ P +P Y + +G Sbjct: 93 ITVEPDAVVITTGSSGGFLLAFLACFDAGDRVAMASPGYPCYRNILSALGCE-------- 144 Query: 188 KYQNVVYMPCGPNNSFFPDL----AMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKT 243 VV +PCGP F P + P + SP NPTG V ++L + + Sbjct: 145 ----VVEIPCGPQTRFQPTAQMLAEIDPPLRGVVVASPANPTGTVIPPEELAAIASWCDA 200 Query: 244 NGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELL 303 + +I D Y + G+P++ +R A+ V+SFSK+ TG RLGW ++P L Sbjct: 201 SDVRLISDEVYHGLVYQGAPQTSCAWQTSR-NAVVVNSFSKYYAMTGWRLGWLLVPTVLR 259 Query: 304 YSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILMDTL 363 + ++Q ++ + E Y NR +L+D L Sbjct: 260 --------RAVDCLTGNFTICPPVLSQIAAVSAFTPEATAEADGNLASYAINRSLLLDGL 311 Query: 364 VSLGLKVYGG-VNAPYLWVHFKG--SKSWDVFNEILENTHIITVPGSGFGPG-GEEYLRI 419 +G+ A Y++ S S +++L +T + PG F G ++RI Sbjct: 312 RRIGIDRLAPTDGAFYVYADVSDFTSDSLAFCSKLLADTGVAIAPGIDFDTARGGSFVRI 371 Query: 420 SGFGRRDHIVEASKRLQNFFNTR 442 S G I EA +R+ ++ ++ Sbjct: 372 SFAGPSGDIEEALRRIGSWLPSQ 394 >3H14-A nrPDB Length = 391 Score = 280 bits (717), Expect = 6e-76, Method: Composition-based stats. Identities = 86/400 (21%), Positives = 148/400 (37%), Gaps = 39/400 (9%) Query: 52 LFPEINRRELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLE 111 F ++ E + ++I + G P ++ + GY + Sbjct: 13 PFIVMDVMEAARRAEEAGRRIIHMEVGQPGTGAPRGAVEALAKSLETDAL-----GYTVA 67 Query: 112 QGNKTLRKAIAETF--YRDLHVKSNEVFVSDGAQSD-ISRLQLLLGSNVTIAVQDPTFPA 168 G LR+ IA + + + + V ++ G+ + L S + + P +P+ Sbjct: 68 LGLPALRQRIARLYGEWYGVDLDPGRVVITPGSSGGFLLAFTALFDSGDRVGIGAPGYPS 127 Query: 169 YIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDV--IFFCSPNNPTG 226 Y +G V +P P N P A D+ + SP NPTG Sbjct: 128 YRQILRALGLVP------------VDLPTAPENRLQPVPADFAGLDLAGLMVASPANPTG 175 Query: 227 YVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFA 286 + + L++ A+ G+ I D Y + + E+ ++SFSK+ Sbjct: 176 TMLDHAAMGALIEAAQAQGASFISDEIYHGIEYEAKAVTALELTDECY---VINSFSKYF 232 Query: 287 GFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIR 346 TG R+GW ++P++ + RI F A + +Q LA + E++ Sbjct: 233 SMTGWRVGWMVVPED--------QVRVVERIAQNMFICAPHASQVAALA--ALDCDAELQ 282 Query: 347 SVNNYYKENRKILMDTLVSLGL-KVYGGVNAPYLWVHFKG--SKSWDVFNEILENTHIIT 403 + + YK NRK++++ L G ++ A Y++ S EILE + Sbjct: 283 ANLDVYKANRKLMLERLPKAGFTRIAPPDGAFYVYADVSDLTDDSRAFAAEILEKAGVAV 342 Query: 404 VPGSGFGPG-GEEYLRISGFGRRDHIVEASKRLQNFFNTR 442 PG F P G LR S I E RL+ F R Sbjct: 343 TPGLDFDPERGAGTLRFSYARATADIEEGLDRLEAFMQAR 382 >2O1B-A nrPDB Length = 404 Score = 280 bits (717), Expect = 7e-76, Method: Composition-based stats. Identities = 88/407 (21%), Positives = 162/407 (39%), Gaps = 28/407 (6%) Query: 38 LVRNVNLEKLKNNYLFPEINRRELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAH 97 + R ++ K + + + +H + LI++ G P P+ I H Sbjct: 15 VPRGSHMISNKLANIPDSYFGKTMGRKIEHGPLPLINMAVGIPDGPTPQGIIDHFQKA-- 72 Query: 98 GLSTVEGYRGYGLEQGNKTLRKAIAETFYRDLHV---KSNEVFVSDGAQSDISRL-QLLL 153 L+ E + YG G + ++AI + + R +V K +EV + G ++ + + ++ Sbjct: 73 -LTIPEN-QKYGAFHGKEAFKQAIVDFYQRQYNVTLDKEDEVCILYGTKNGLVAVPTCVI 130 Query: 154 GSNVTIAVQDPTFPAYIDSSVII-GQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPR 212 + + DP + Y+ ++ G+ + + Y P+ S D + + Sbjct: 131 NPGDYVLLPDPGYTDYLAGVLLADGKPVPLNLEPPHYL--------PDWSKV-DSQIIDK 181 Query: 213 TDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGA 272 T +I+ PNNPTG A+++ + + K + I+ D AY AF D SI Sbjct: 182 TKLIYLTYPNNPTGSTATKEVFDEAIAKFKGTDTKIVHDFAYGAFGFDAKNPSILASENG 241 Query: 273 REVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAG 332 ++VAIE+ S SK +G R+G+++ ++ I + T + G Q Sbjct: 242 KDVAIEIYSLSKGYNMSGFRVGFAVGNKDM--------IQALKKYQTHTNAGMFGALQDA 293 Query: 333 GLACLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSWDVF 392 + L+ + +N +K R L L Y+W+ + F Sbjct: 294 AIYALNHYD-DFLEEQSNVFKTRRDRFEAMLAKADLPFVHAKGGIYVWLETPPGYDSEQF 352 Query: 393 NEIL-ENTHIITVPGSGFGPGGEEYLRISGFGRRDHIVEASKRLQNF 438 + L + I+ PG FG G Y+RIS + EA+ RL Sbjct: 353 EQFLVQEKSILVAPGKPFGENGNRYVRISLALDDQKLDEAAIRLTEL 399 >1U08-A nrPDB Length = 386 Score = 277 bits (707), Expect = 1e-74, Method: Composition-based stats. Identities = 72/395 (18%), Positives = 151/395 (38%), Gaps = 48/395 (12%) Query: 62 EHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAI 121 + Q I+L G P + +++ +G Y G + LR+AI Sbjct: 22 QMSALAQQHQAINLSQGFPDFDGPRYLQERLAHHVA-----QGANQYAPMTGVQALREAI 76 Query: 122 AETFYRDLHVKSN---EVFVSDGAQSDI-SRLQLLLGSNVTIAVQDPTFPAYIDSSVIIG 177 A+ R + + ++ V+ GA + + + L+ + + DP++ +Y + + G Sbjct: 77 AQKTERLYGYQPDADSDITVTAGATEALYAAITALVRNGDEVICFDPSYDSYAPAIALSG 136 Query: 178 Q--------TGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVA 229 HF +++ + ++ RT ++ +P+NP+ V Sbjct: 137 GIVKRMALQPPHFRVDWQEFAAL----------------LSERTRLVILNTPHNPSATVW 180 Query: 230 SRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGS-PRSIYEIPGAREVAIEVSSFSKFAGF 288 + L + +I D Y S+ P RE A+ VSSF K Sbjct: 181 QQADFAALWQAIAGHEIFVISDEVYEHINFSQQGHASVLAHPQLRERAVAVSSFGKTYHM 240 Query: 289 TGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSV 348 TG ++G+ + P + I H+ +T S N + + LA + + ++ Sbjct: 241 TGWKVGYCVAPAPISAE-----IRKVHQYLTFSVNTPAQL----ALADMLRAEPEHYLAL 291 Query: 349 NNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSWD---VFNEILENTHIITVP 405 ++Y++ R IL++ L L++ +L V + + D + + + +P Sbjct: 292 PDFYRQKRDILVNALNESRLEILPCEGTYFLLVDYSAVSTLDDVEFCQWLTQEHGVAAIP 351 Query: 406 GSGF--GPGGEEYLRISGFGRRDHIVEASKRLQNF 438 S F P + +R+ + ++ A++RL+ Sbjct: 352 LSVFCADPFPHKLIRLCFAKKESTLLAAAERLRQL 386 >2ZJG-A nrPDB Length = 410 Score = 268 bits (686), Expect = 3e-72, Method: Composition-based stats. Identities = 77/419 (18%), Positives = 147/419 (35%), Gaps = 47/419 (11%) Query: 57 NRRELEHIEKHPNVQ---------LISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRG 107 N + +E ++ + V+ +++LG G P + +S A + + RG Sbjct: 1 NAKRIEGLDSNVWVEFTKLAADPSVVNLGQGFPDISPPSYVKEELSKAAFIDNMNQYTRG 60 Query: 108 YGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDI-SRLQLLLGSNVTIAVQDPTF 166 +G K L + + R + + E+ V+ GA + + +Q L+ + + P + Sbjct: 61 FGHPALVKALSCLYGKIYQRQID-PNEEILVAVGAYGSLFNSIQGLVDPGDEVIIMVPFY 119 Query: 167 PAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFP---DLAMTPRTDVIFFCSPNN 223 Y + G F K + + + +F P + + +T I +P+N Sbjct: 120 DCYEPMVRMAGAVPVFIPLRSKPTDGMK-WTSSDWTFDPRELESKFSSKTKAIILNTPHN 178 Query: 224 PTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGS-PRSIYEIPGAREVAIEVSSF 282 P G V +R++L + D + ++ I D Y + G I +PG E I + S Sbjct: 179 PLGKVYTRQELQVIADLCVKHDTLCISDEVYEWLVYTGHTHVKIATLPGMWERTITIGSA 238 Query: 283 SKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACL----- 337 K TG +LGWSI P L I + SF + QA Sbjct: 239 GKTFSVTGWKLGWSIGPAHL--------IKHLQTVQQNSFYTCATPLQAALAEAFWIDIK 290 Query: 338 -SSGGLKEIRSVNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFK------------ 384 S+ + R ++ L S+GLK ++ Sbjct: 291 RMDDPECYFNSLPKELEVKRDRMVRLLNSVGLKPIVPDGGYFIIADVSSLGADLSDMNSD 350 Query: 385 GSKSWDVFNEILENTHIITVPGSGF-----GPGGEEYLRISGFGRRDHIVEASKRLQNF 438 + + ++ + +P S F P E+ +R + + A + + + Sbjct: 351 EPYDYKFVKWMTKHKKLTAIPVSAFCDSKSKPHFEKLVRFCFIKKDSTLDAAEEIFRAW 409 >1V2E-A nrPDB Length = 381 Score = 268 bits (684), Expect = 5e-72, Method: Composition-based stats. Identities = 85/375 (22%), Positives = 142/375 (37%), Gaps = 32/375 (8%) Query: 70 VQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYRDL 129 + ++LG G + P P + + Y G LR+A+AE F Sbjct: 25 LGAVNLGQGFPSNPPPPFLLEAVRRALGRQDQ------YAPPAGLPALREALAEEFA--- 75 Query: 130 HVKSNEVFVSDGAQSDIS-RLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKK 188 V+ V V+ GA + LQ L+G + V +P F Y+ + + G Sbjct: 76 -VEPESVVVTSGATEALYVLLQSLVGPGDEVVVLEPFFDVYLPDAFLAGAKARLVRLDLT 134 Query: 189 YQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSII 248 + + + A+TPRT + +P NPTG V ++L + A+ + + Sbjct: 135 PEGFRL------DLSALEKALTPRTRALLLNTPMNPTGLVFGERELEAIARLARAHDLFL 188 Query: 249 IFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGF 308 I D Y PR + E A E V S K TG R+GW + P E + Sbjct: 189 ISDEVYDELYYGERPRRLREF--APERTFTVGSAGKRLEATGYRVGWIVGPKEFM----- 241 Query: 309 PIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILMDTLVSLGL 368 P + TSF+ + + A + ++ Y+ R +L L ++GL Sbjct: 242 PRLAGMR--QWTSFSAPTPLQAGVAEALKLARREGFYEALREGYRRRRDLLAGGLRAMGL 299 Query: 369 KVYGGVNAPYLWVHFKGSKSWDVFNEILENTHIITVPGSGF--GPGGEEYLRISGFGRRD 426 +VY +L G WD F ++E + +P S F ++ R + + Sbjct: 300 RVYVPEGTYFLMAELPG---WDAFR-LVEEARVALIPASAFYLEDPPKDLFRFAFCKTEE 355 Query: 427 HIVEASKRLQNFFNT 441 + A +RL N+ Sbjct: 356 ELHLALERLGRVVNS 370 >3DYD-A nrPDB Length = 427 Score = 265 bits (677), Expect = 3e-71, Method: Composition-based stats. Identities = 79/394 (20%), Positives = 141/394 (35%), Gaps = 38/394 (9%) Query: 63 HIEKHPNVQLISLGTGDTTE----PIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLR 118 ++ +PN +ISL GD T P ++T M + Y GY G + R Sbjct: 47 KVKPNPNKTMISLSIGDPTVFGNLPTDPEVTQAMKDALDS----GKYNGYAPSIGFLSSR 102 Query: 119 KAIAETFY-RDLHVKSNEVFVSDGAQSDISRLQLLL-GSNVTIAVQDPTFPAYIDSSVII 176 + IA ++ + +++ +V ++ G I +L I V P F Y + + Sbjct: 103 EEIASYYHCPEAPLEAKDVILTSGCSQAIDLCLAVLANPGQNILVPRPGFSLYKTLAESM 162 Query: 177 GQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLA-----MTPRTDVIFFCSPNNPTGYVASR 231 G + P S+ DL + +T + +P+NP G V S+ Sbjct: 163 GIEVKLYN------------LLPEKSWEIDLKQLEYLIDEKTACLIVNNPSNPCGSVFSK 210 Query: 232 KQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGV 291 + L +++ A I+ D Y + + +K G Sbjct: 211 RHLQKILAVAARQCVPILADEIYGDMVFSDCKYEPLATLSTDVPILSCGGLAKRWLVPGW 270 Query: 292 RLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNY 351 RLGW +I D I D ++ G I Q + L + + ++ Sbjct: 271 RLGWILIHDRR--DIFGNEIRDGLVKLSQRILGPCTIVQGALKSILCRTPGEFYHNTLSF 328 Query: 352 YKENRKILMDTLVSL-GLKVYGGVNAPYLWV-----HFKGSKSWDVFNE-ILENTHIITV 404 K N + L ++ GL+ A YL V HF ++ F E ++ + + Sbjct: 329 LKSNADLCYGALAAIPGLRPVRPSGAMYLMVGIEMEHFPEFENDVEFTERLVAEQSVHCL 388 Query: 405 PGSGFGPGGEEYLRISGFGRRDHIVEASKRLQNF 438 P + F ++R+ ++EA R+Q F Sbjct: 389 PATCF--EYPNFIRVVITVPEVMMLEACSRIQEF 420 >4WP0-A nrPDB Length = 472 Score = 263 bits (673), Expect = 8e-71, Method: Composition-based stats. Identities = 78/423 (18%), Positives = 143/423 (33%), Gaps = 47/423 (11%) Query: 55 EINRRELEHIEKHPNV---------QLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGY 105 ++ R L+ I+ +P V +++LG G P P+ + G + Y Sbjct: 4 QLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQY 63 Query: 106 RG-YGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQDP 164 +G K L E +++ N + G + + Q L+ + + +P Sbjct: 64 TKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEP 123 Query: 165 TFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFP-DLA--MTPRTDVIFFCSP 221 F Y +++ G F + N P +LA T RT + +P Sbjct: 124 FFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTP 183 Query: 222 NNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGS-PRSIYEIPGAREVAIEVS 280 NNP G V SR++L + + + + I D Y + DG SI +PG E + + Sbjct: 184 NNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIG 243 Query: 281 SFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLA----- 335 S K TG ++GW + PD ++ + S +QA Sbjct: 244 SAGKTFSATGWKVGWVLGPDHIM--------KHLRTVHQNSVFHCPTQSQAAVAESFERE 295 Query: 336 -CLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLKVYGGVNAPYL----------WVHFK 384 L + R ++ +L S+GLK + +L Sbjct: 296 QLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLP 355 Query: 385 G----SKSWDVFNEILENTHIITVPGSGFGPGGE-----EYLRISGFGRRDHIVEASKRL 435 G +++N ++ +P S F Y+R + ++L Sbjct: 356 GAVDEPYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKL 415 Query: 436 QNF 438 + + Sbjct: 416 RKW 418 >3FVS-A nrPDB Length = 422 Score = 263 bits (673), Expect = 8e-71, Method: Composition-based stats. Identities = 78/423 (18%), Positives = 143/423 (33%), Gaps = 47/423 (11%) Query: 55 EINRRELEHIEKHPNV---------QLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGY 105 ++ R L+ I+ +P V +++LG G P P+ + G + Y Sbjct: 4 QLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQY 63 Query: 106 RG-YGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQDP 164 +G K L E +++ N + G + + Q L+ + + +P Sbjct: 64 TKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEP 123 Query: 165 TFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFP-DLA--MTPRTDVIFFCSP 221 F Y +++ G F + N P +LA T RT + +P Sbjct: 124 FFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTP 183 Query: 222 NNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGS-PRSIYEIPGAREVAIEVS 280 NNP G V SR++L + + + + I D Y + DG SI +PG E + + Sbjct: 184 NNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIG 243 Query: 281 SFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLA----- 335 S K TG ++GW + PD ++ + S +QA Sbjct: 244 SAGKTFSATGWKVGWVLGPDHIM--------KHLRTVHQNSVFHCPTQSQAAVAESFERE 295 Query: 336 -CLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLKVYGGVNAPYL----------WVHFK 384 L + R ++ +L S+GLK + +L Sbjct: 296 QLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLP 355 Query: 385 G----SKSWDVFNEILENTHIITVPGSGFGPGGE-----EYLRISGFGRRDHIVEASKRL 435 G +++N ++ +P S F Y+R + ++L Sbjct: 356 GAVDEPYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKL 415 Query: 436 QNF 438 + + Sbjct: 416 RKW 418 >3PDX-A nrPDB Length = 402 Score = 260 bits (665), Expect = 7e-70, Method: Composition-based stats. Identities = 77/394 (19%), Positives = 141/394 (35%), Gaps = 38/394 (9%) Query: 63 HIEKHPNVQLISLGTGDTTE----PIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLR 118 ++ +PN +ISL GD T P ++T M + Y GY G + R Sbjct: 24 KVKPNPNKTVISLSIGDPTVFGNLPTDPEVTQAMKDALDS----GKYNGYAPSIGYLSSR 79 Query: 119 KAIAETFY-RDLHVKSNEVFVSDGAQSDISRLQLLL-GSNVTIAVQDPTFPAYIDSSVII 176 + +A ++ + +++ +V ++ G I +L I + P F Y + + Sbjct: 80 EEVASYYHCPEAPLEAKDVILTSGCSQAIELCLAVLANPGQNILIPRPGFSLYRTLAESM 139 Query: 177 GQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLA-----MTPRTDVIFFCSPNNPTGYVASR 231 G + P S+ DL + +T + +P+NP G V S+ Sbjct: 140 GIEVKLYN------------LLPEKSWEIDLKQLESLIDEKTACLVVNNPSNPCGSVFSK 187 Query: 232 KQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGV 291 + L +++ A+ I+ D Y + + +K G Sbjct: 188 RHLQKILAVAERQCVPILADEIYGDMVFSDCKYEPMATLSTNVPILSCGGLAKRWLVPGW 247 Query: 292 RLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNY 351 RLGW +I D I D ++ G I Q + L + + ++ Sbjct: 248 RLGWILIHDRR--DIFGNEIRDGLVKLSQRILGPCTIVQGALKSILQRTPQEFYQDTLSF 305 Query: 352 YKENRKILMDTLVSL-GLKVYGGVNAPYLWV-----HFKGSKSWDVFNE-ILENTHIITV 404 K N + L ++ GL+ A YL V HF ++ F E ++ + + Sbjct: 306 LKSNADLCYGALSAIPGLQPVRPSGAMYLMVGIEMEHFPEFENDVEFTERLIAEQSVHCL 365 Query: 405 PGSGFGPGGEEYLRISGFGRRDHIVEASKRLQNF 438 P + F + R+ ++EA R+Q F Sbjct: 366 PATCF--EYPNFFRVVITVPEVMMLEACSRIQEF 397 >3JTX-A nrPDB Length = 396 Score = 255 bits (652), Expect = 2e-68, Method: Composition-based stats. Identities = 86/421 (20%), Positives = 156/421 (37%), Gaps = 48/421 (11%) Query: 41 NVNLEKLKNNYLFPEINRRELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLS 100 N L++LK Y F ++ ++ I ++ + L G+ P P+ IT ++ H L Sbjct: 3 NTLLKQLKP-YPFARLHE-AMQGISAPEGMEAVPLHIGEPKHPTPKVITDALTASLHELE 60 Query: 101 TVEGYRGYGLEQGNKTLRKAIAETFYRDLH----VKSNEVFVSDGAQSDISRL-QLLLGS 155 Y L G LR+A A R NE+ G++ + Q +L Sbjct: 61 ------KYPLTAGLPELRQACANWLKRRYDGLTVDADNEILPVLGSREALFSFVQTVLNP 114 Query: 156 -----NVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMT 210 I +P + Y ++++ G HF N P+ + + Sbjct: 115 VSDGIKPAIVSPNPFYQIYEGATLLGGGEIHF-------ANCPAPSFNPDWRSISE-EVW 166 Query: 211 PRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPR-----S 265 RT ++F CSPNNP+G V ++ D G II D Y+ DG+ + Sbjct: 167 KRTKLVFVCSPNNPSGSVLDLDGWKEVFDLQDKYGFIIASDECYSEIYFDGNKPLGCLQA 226 Query: 266 IYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGA 325 ++ +R+ + +S SK + G+R G+ EL + +F T + Sbjct: 227 AAQLGRSRQKLLMFTSLSKRSNVPGLRSGFVAGDAEL--------LKNFLLYRTYHGSAM 278 Query: 326 SNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFKG 385 S Q +A + + Y+E + ++ L + V + Y+W+ Sbjct: 279 SIPVQRASIAAWDDE--QHVIDNRRLYQEKFERVIPILQQV-FDVKLPDASFYIWLKVPD 335 Query: 386 SKSWDVFNEILENTHIITVPGSGF------GPGGEEYLRISGFGRRDHIVEASKRLQNFF 439 + + I +PG G GE Y+RI+ V+A++ + + + Sbjct: 336 GDDLAFARNLWQKAAIQVLPGRFLARDTEQGNPGEGYVRIALVADVATCVKAAEDIVSLY 395 Query: 440 N 440 Sbjct: 396 R 396 >3ELE-A nrPDB Length = 398 Score = 252 bits (644), Expect = 2e-67, Method: Composition-based stats. Identities = 81/400 (20%), Positives = 143/400 (35%), Gaps = 31/400 (7%) Query: 55 EINRRELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGN 114 E+ + + G+ + P P+ + + +V GY QG+ Sbjct: 20 ELFEYGKKRAAIVGKENVYDFSIGNPSIPAPQIVNDTIKELVTDYDSV-ALHGYTSAQGD 78 Query: 115 KTLRKAIAETF--YRDLHVKSNEVFVSDGAQSDISRLQLLLGSN--VTIAVQDPTFPAYI 170 R AIAE H ++ ++++ GA + +S L S+ P FP Y Sbjct: 79 VETRAAIAEFLNNTHGTHFNADNLYMTMGAAASLSICFRALTSDAYDEFITIAPYFPEYK 138 Query: 171 DSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVAS 230 G ++ + + + + T + SPNNP+G V S Sbjct: 139 VFVNAAGARLVEVPADTEHFQI--------DFDALEERINAHTRGVIINSPNNPSGTVYS 190 Query: 231 RKQLHQLVDFAKTN------GSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSK 284 + + +L D + II D Y + DG + + + S+SK Sbjct: 191 EETIKKLSDLLEKKSKEIGRPIFIIADEPYREIVYDGIKVPF--VTKYYDNTLVCYSYSK 248 Query: 285 FAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKE 344 G R+G+ ++PDE +Y + A ++ Q + C + G Sbjct: 249 SLSLPGERIGYVLVPDE-VYDKAELYAAVCGAGRALGYVCAPSLFQKMIVKCQGATGD-- 305 Query: 345 IRSVNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSWDVFNEILENTHIITV 404 N YKENR +L + L +G + A Y++V + F E + ++ V Sbjct: 306 ----INAYKENRDLLYEGLTRIGYHCFKPDGAFYMFVK-ALEDDSNAFCEKAKEEDVLIV 360 Query: 405 PGSGFGPGGEEYLRISGFGRRDHIVEASKRLQNFFNTRTK 444 GFG G ++RIS R+ I + + + K Sbjct: 361 AADGFGCPG--WVRISYCVDREMIKHSMPAFEKIYKKYNK 398 >4DQ6-A nrPDB Length = 391 Score = 248 bits (634), Expect = 3e-66, Method: Composition-based stats. Identities = 86/407 (21%), Positives = 143/407 (35%), Gaps = 36/407 (8%) Query: 50 NYLFPEINRRE-------LEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTV 102 NY F EI R E +K+ L+ + D I + N Sbjct: 5 NYNFNEIVDRSNNFSSKWSEMEKKYGTNDLLPMWVADMDFKAAPCIIDSLKNRLEQEI-- 62 Query: 103 EGYRGYGLEQGNKTLRKAIAETFYRD--LHVKSNEVFVSDGAQSDISRL-QLLLGSNVTI 159 YG + ++I YR +KS + S G IS L L +N I Sbjct: 63 -----YGYTTRPDSYNESIVNWLYRRHNWKIKSEWLIYSPGVIPAISLLINELTKANDKI 117 Query: 160 AVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFC 219 +Q+P + + +S V +K +N Y+ + + C Sbjct: 118 MIQEPVYSPF-NSVVKNNNRELIISPLQKLENGNYIMDYEDIEN-----KIKDVKLFILC 171 Query: 220 SPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEI--PGAREVAI 277 +P+NP G V ++ +L +L D + II D ++ I + I Sbjct: 172 NPHNPVGRVWTKDELKKLGDICLKHNVKIISDEIHSDIILKKHKHIPMASISKEFEKNTI 231 Query: 278 EVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACL 337 + +K G++ + ++PDE Y + F RI N S +A Sbjct: 232 TCMAPTKTFNIAGLQSSYVVLPDEKDYKLLD---DAFTRIDIKRNNCFSLVATEASY--- 285 Query: 338 SSGGLKEIRSVNNYYKENRKILMDTLVS--LGLKVYGGVNAPYLWVHFK--GSKSWDVFN 393 + G + S Y + N + + LKV LWV F G ++ + Sbjct: 286 -NNGESWLESFLEYLESNIDFAIKYINENMPKLKVRKPEGTYLLWVDFSALGLSDEELES 344 Query: 394 EILENTHIITVPGSGFGPGGEEYLRISGFGRRDHIVEASKRLQNFFN 440 +++ + G+ FG GG Y RI+ R + EA R++N N Sbjct: 345 ILVQKGKVALNQGNSFGIGGSGYQRINLACPRSMLEEALIRIKNAIN 391 >1BW0-A nrPDB Length = 416 Score = 238 bits (607), Expect = 4e-63, Method: Composition-based stats. Identities = 82/419 (19%), Positives = 141/419 (33%), Gaps = 44/419 (10%) Query: 49 NNYLFPEINRRELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGY 108 +F I +I L GD T ++ + GY Sbjct: 12 AGLVFNPIRTVSDNAKPSPSPKPIIKLSVGDPTLDKNLLTSAAQIKKLKEAIDSQECNGY 71 Query: 109 GLEQGNKTLRKAIAETFY---------RDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTI 159 G+ R+A+A + + VK N V S G+ + + + + Sbjct: 72 FPTVGSPEAREAVATWWRNSFVHKEELKSTIVKDNVVLCSGGSHGILMAITAICDAGDYA 131 Query: 160 AVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAM-----TPRTD 214 V P FP Y G HF+ C P N + DL +T Sbjct: 132 LVPQPGFPHYETVCKAYGIGMHFYN------------CRPENDWEADLDEIRRLKDDKTK 179 Query: 215 VIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGS-----PRSIYEI 269 ++ +P+NP G SRK + +V A+ + D YA + G S+ + Sbjct: 180 LLIVTNPSNPCGSNFSRKHVEDIVRLAEELRLPLFSDEIYAGMVFKGKDPNATFTSVADF 239 Query: 270 PGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIA 329 I + +K G RLGW + D + NG + R+ G + Sbjct: 240 ETTVPRVI-LGGTAKNLVVPGWRLGWLLYVDP--HGNGPSFLEGLKRVGMLVC-GPCTVV 295 Query: 330 QAGGLACLSSGGLKEIRSVNNYYKENRKILMDTLVS-LGLKVYGGVNAPYLWVHFKGSKS 388 QA L + + + + +E+ L + + +GL A YL K Sbjct: 296 QAALGEALLNTPQEHLDQIVAKIEESAMYLYNHIGECIGLAPTMPRGAMYLMSRIDLEKY 355 Query: 389 WDVFNEI------LENTHIITVPGSGFGPGGEEYLRISGFGRRDHIVEASKRLQNFFNT 441 D+ ++ LE ++ +PG+ F G + R++ + EA +R++ F Sbjct: 356 RDIKTDVEFFEKLLEEENVQVLPGTIFHAPG--FTRLTTTRPVEVYREAVERIKAFCQR 412 >4CVQ-A nrPDB Length = 431 Score = 233 bits (595), Expect = 9e-62, Method: Composition-based stats. Identities = 76/402 (18%), Positives = 146/402 (36%), Gaps = 41/402 (10%) Query: 62 EHIEKHPNVQLISLGTGDTT---EPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLR 118 + +++ L G+ P++I + + +GY +G + R Sbjct: 51 AKRLEEEGNKVLKLNIGNPAPFGFDAPDEI------LVDVIRNLPTAQGYCDSKGLYSAR 104 Query: 119 KAIAETFYRD--LHVKSNEVFVSDGAQSDIS-RLQLLLGSNVTIAVQDPTFPAYIDSSVI 175 KAI + + V ++++ +G I +Q LL S + V P +P + + + Sbjct: 105 KAIMQHYQARGMRDVTVEDIYIGNGVSELIVQAMQALLNSGDEMLVPAPDYPLWTAAVSL 164 Query: 176 IGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDL-----AMTPRTDVIFFCSPNNPTGYVAS 230 + C ++ +FPDL +TPRT I +PNNPTG V S Sbjct: 165 SSGKAVHYL------------CDESSDWFPDLDDIRAKITPRTRGIVIINPNNPTGAVYS 212 Query: 231 RKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTG 290 ++ L ++V+ A+ + II D Y + D + + I + SK G Sbjct: 213 KELLMEIVEIARQHNLIIFADEIYDKILYDDAEHHSIAPLAPDLLTITFNGLSKTYRVAG 272 Query: 291 VRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGG--LKEIRSV 348 R GW ++ ++ G+ I + + A+ AQ L + I Sbjct: 273 FRQGWMVLNGPKKHAKGY--IEGLEMLASMRL-CANVPAQHAIQTALGGYQSISEFITPG 329 Query: 349 NNYYKENRKILMDTLVSL-GLKVYGGVNAPYLWVHFKGS-----KSWDVFNEILENTHII 402 Y++ R + + + G+ A Y++ + + L ++ Sbjct: 330 GRLYEQ-RNRAWELINDIPGVSCVKPRGALYMFPKIDAKRFNIHDDQKMVLDFLLQEKVL 388 Query: 403 TVPGSGFGPGGEEYLRISGFGRRDHIVEASKRLQNFFNTRTK 444 V G+ F ++ RI R D I + + F + + Sbjct: 389 LVQGTAFNWPWPDHFRIVTLPRVDDIELSLSKFARFLSGYHQ 430 >3AV7-A nrPDB Length = 448 Score = 232 bits (592), Expect = 2e-61, Method: Composition-based stats. Identities = 70/398 (17%), Positives = 137/398 (34%), Gaps = 29/398 (7%) Query: 59 RELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLR 118 REL + + ++ ++ G + E I + + YG +G LR Sbjct: 67 RELLKLVETSDIISLAGGLPNPKTFPKEIIRDILVEIMEKYADK--ALQYGTTKGFTPLR 124 Query: 119 KAIAETFYRDLHV-KSNEVFVSDGAQSDISRL-QLLLGSNVTIAVQDPTFPAYIDSSVII 176 + + + + + + N++ ++ G+Q + + ++ L + V+ PT+ A + + Sbjct: 125 ETLMKWLGKRYGISQDNDIMITSGSQQALDLIGRVFLNPGDIVVVEAPTYLAALQAFNFY 184 Query: 177 GQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSP--NNPTGYVASRKQL 234 + V + +L + + + P NP G + + Sbjct: 185 EPQYIQIPLDDEGMKVEIL-----EEKLKELKSQGKKVKVVYTVPTFQNPAGVTMNEDRR 239 Query: 235 HQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLG 294 L++ A I++ D Y G+P + I + +FSK G R+G Sbjct: 240 KYLLELASEYDFIVVEDDPYGELRYSGNPEKKIKALDNEGRVIYLGTFSKILA-PGFRIG 298 Query: 295 WSIIPDELLYSNGFPIINDFHRIVTTSFNGASNI-AQAGGLACLSSGGLK-EIRSVNNYY 352 W + P I I S + +N+ Q + G L+ I + +Y Sbjct: 299 WMVG---------DPGIIRKMEIAKQSTDLCTNVFGQVVAWRYVDGGYLEKHIPEIRKFY 349 Query: 353 KENRKILMDTLVSL---GLKVYGGVNAPYLWVHFKGSKSWDVFNEILENTHIITVPGSGF 409 K R +++ L G+K ++WV E + VPG F Sbjct: 350 KPRRDAMLEALEEFMPEGVKWTKPEGGMFIWVTLPDGIDSKKMLERAIKKGVAYVPGEAF 409 Query: 410 --GPGGEEYLRISGF-GRRDHIVEASKRLQNFFNTRTK 444 + +R++ D I+E KRL K Sbjct: 410 YAHRDVKNTMRLNFTYVDEDKIMEGIKRLAETIKEELK 447 >1X0M-A nrPDB Length = 403 Score = 231 bits (588), Expect = 7e-61, Method: Composition-based stats. Identities = 70/398 (17%), Positives = 137/398 (34%), Gaps = 29/398 (7%) Query: 59 RELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLR 118 REL + + ++ ++ G + E I + + YG +G LR Sbjct: 22 RELLKLVETSDIISLAGGLPNPKTFPKEIIRDILVEIMEKYADK--ALQYGTTKGFTPLR 79 Query: 119 KAIAETFYRDLHV-KSNEVFVSDGAQSDISRL-QLLLGSNVTIAVQDPTFPAYIDSSVII 176 + + + + + + N++ ++ G+Q + + ++ L + V+ PT+ A + + Sbjct: 80 ETLMKWLGKRYGISQDNDIMITSGSQQALDLIGRVFLNPGDIVVVEAPTYLAALQAFNFY 139 Query: 177 GQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSP--NNPTGYVASRKQL 234 + V + +L + + + P NP G + + Sbjct: 140 EPQYIQIPLDDEGMKVEIL-----EEKLKELKSQGKKVKVVYTVPTFQNPAGVTMNEDRR 194 Query: 235 HQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLG 294 L++ A I++ D Y G+P + I + +FSK G R+G Sbjct: 195 KYLLELASEYDFIVVEDDPYGELRYSGNPEKKIKALDNEGRVIYLGTFSKILA-PGFRIG 253 Query: 295 WSIIPDELLYSNGFPIINDFHRIVTTSFNGASNI-AQAGGLACLSSGGLK-EIRSVNNYY 352 W + P I I S + +N+ Q + G L+ I + +Y Sbjct: 254 WMVG---------DPGIIRKMEIAKQSTDLCTNVFGQVVAWRYVDGGYLEKHIPEIRKFY 304 Query: 353 KENRKILMDTLVSL---GLKVYGGVNAPYLWVHFKGSKSWDVFNEILENTHIITVPGSGF 409 K R +++ L G+K ++WV E + VPG F Sbjct: 305 KPRRDAMLEALEEFMPEGVKWTKPEGGMFIWVTLPDGIDSKKMLERAIKKGVAYVPGEAF 364 Query: 410 --GPGGEEYLRISGF-GRRDHIVEASKRLQNFFNTRTK 444 + +R++ D I+E KRL K Sbjct: 365 YAHRDVKNTMRLNFTYVDEDKIMEGIKRLAETIKEELK 402 >3OP7-A nrPDB Length = 375 Score = 229 bits (584), Expect = 2e-60, Method: Composition-based stats. Identities = 77/348 (22%), Positives = 140/348 (40%), Gaps = 42/348 (12%) Query: 108 YGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSD-ISRLQLLLGSNVTIAVQDPTF 166 YG +G+ +K++++ + VK ++ ++GA + L L+ + PT+ Sbjct: 59 YGWIEGSPAFKKSVSQLY---TGVKPEQILQTNGATGANLLVLYSLIEPGDHVISLYPTY 115 Query: 167 PAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLA-----MTPRTDVIFFCSP 221 D +G + N + PDL + P T +I + Sbjct: 116 QQLYDIPKSLGAEVDLWQIE------------EENGWLPDLEKLRQLIRPTTKMICINNA 163 Query: 222 NNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSS 281 NNPTG V R L +LV+ A G+ I+ D Y +F E P SI E+ + I V+S Sbjct: 164 NNPTGAVMDRTYLEELVEIASEVGAYILSDEVYRSFSELDVP-SIIEV---YDKGIAVNS 219 Query: 282 FSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGG 341 SK G+R+GW ++ ++ D+ I F+ +A L+ Sbjct: 220 LSKTYSLPGIRIGWVAANHQV--TDILRDYRDYTMICAGVFDDL--------VAQLALAH 269 Query: 342 LKEIRSVNNY-YKENRKILMDTLVSLGL-KVYGG--VNAPYLWVHFKGSKSWDVFNEILE 397 +EI N + +EN IL + L V+ ++ + D ++L+ Sbjct: 270 YQEILERNRHILEENLAILDQWIEEEPLVSYIRPAVVSTSFVKIAV-DMPMEDFCLQLLQ 328 Query: 398 NTHIITVPGSGFGPGGEEYLRISGFGRRDHIVEASKRLQNFFNTRTKH 445 ++ VPG+ F G Y+R+ ++ +++ ++L F K Sbjct: 329 EHGVLLVPGNRFERDG--YVRLGFACEQETLIKGLEKLSQFLRRFDKE 374 >1YIY-A nrPDB Length = 429 Score = 228 bits (580), Expect = 6e-60, Method: Composition-based stats. Identities = 63/396 (15%), Positives = 137/396 (34%), Gaps = 40/396 (10%) Query: 73 ISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYR--DLH 130 ++LG G P+ + ++ A+ + Y G+ L +A+++ + + D Sbjct: 40 LNLGQGFPDYHAPKYALNALAAAANSPDPL--ANQYTRGFGHPRLVQALSKLYSQLVDRT 97 Query: 131 VKS-NEVFVSDGAQSDISR-LQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHE-KTK 187 + EV V+ GA + +Q + + + +P F Y G F K Sbjct: 98 INPMTEVLVTVGAYEALYATIQGHVDEGDEVIIIEPFFDCYEPMVKAAGGIPRFIPLKPN 157 Query: 188 KYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSI 247 K + ++ + +T +I +P+NP G V R +L + + K + Sbjct: 158 KTGGTISSADWVLDNNELEALFNEKTKMIIINTPHNPLGKVMDRAELEVVANLCKKWNVL 217 Query: 248 IIFDSAYAAFIEDG-SPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSN 306 + D Y + + I +PG E I + S K TG ++GW+ P+ L Sbjct: 218 CVSDEVYEHMVFEPFEHIRICTLPGMWERTITIGSAGKTFSLTGWKIGWAYGPEAL---- 273 Query: 307 GFPIINDFHRIVTTSFNGASNIAQAGGLACLSSG------GLKEIRSVNNYYKENRKILM 360 + + + + Q + S++ R + Sbjct: 274 ----LKNLQMVHQNCVYTCATPIQEAIAVGFETELKRLKSPECYFNSISGELMAKRDYMA 329 Query: 361 DTLVSLGLKVYGGVNAPYLWVHFKGSKSWD-------------VFNEILENTHIITVPGS 407 L +G+ ++ + S + ++ + +P S Sbjct: 330 SFLAEVGMNPTVPQGGYFMVADWSSLDSKVDLTQETDARKDYRFTKWMTKSVGLQGIPPS 389 Query: 408 GFGPG-----GEEYLRISGFGRRDHIVEASKRLQNF 438 F GE+++R F + +++ +A++ L+ + Sbjct: 390 AFYSEPNKHLGEDFVRYCFFKKDENLQKAAEILRKW 425 >4IX8-A nrPDB Length = 444 Score = 227 bits (579), Expect = 7e-60, Method: Composition-based stats. Identities = 74/394 (18%), Positives = 141/394 (35%), Gaps = 41/394 (10%) Query: 73 ISLGTGDTTEP----IPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYRD 128 + L GD T P+ +T M + + GY G LR+ ++ + R Sbjct: 70 LRLSIGDPTVDGNLKTPDIVTEAMVDVVRS----GKFNGYPPTVGADNLRQVVSTYWRRF 125 Query: 129 LHVKS-------NEVFVSDGAQSDI-SRLQLLLGSNVTIAVQDPTFPAYIDSSVIIG--Q 178 KS V ++ G I L L I V P+FP Y G Sbjct: 126 CQTKSRQEALKWENVIITSGVSQAIVLALTALCNEGDNILVCAPSFPHYKSVCDSYGIEC 185 Query: 179 TGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLV 238 ++ + +K ++ + G + T +P+NP G SR + ++ Sbjct: 186 RYYYLDPSKSWECDLRAAAGM---------VDSHTKAFVIINPSNPCGSNFSRAHVSDII 236 Query: 239 DFAKTNGSIIIFDSAYAAFI-EDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSI 297 DF + + +I D YA + +G S+ + I + +K+ G R+GWSI Sbjct: 237 DFCQQHQIPLISDEIYAEMVLNNGIFTSVADFDTNVPRLI-LGGTAKYQVCPGWRVGWSI 295 Query: 298 IPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRK 357 + D + + + + +T G ++I Q L + + + K Sbjct: 296 LIDPMNVAGDWAV---GMERLTQLIAGVNSICQEAIARTLLKCPTECTEHIVTQLEAGAK 352 Query: 358 ILMDTLV-SLGLKVYGGVNAPYLWVHF------KGSKSWDVFNEILENTHIITVPGSGFG 410 + L +G+ + + ++ + + + ++L+ ++ +PG FG Sbjct: 353 VYARLLEHDIGISMEAPQASMFVMLKLNLSYFQDLKSDMEFYEKLLDEENVQVLPGEIFG 412 Query: 411 PGGEEYLRISGFGRRDHIVEASKRLQNFFNTRTK 444 G +LR + + EA R+ F K Sbjct: 413 MSG--FLRATVSRPSAVLNEAVDRIIEFCERHKK 444 >3B46-A nrPDB Length = 447 Score = 226 bits (576), Expect = 2e-59, Method: Composition-based stats. Identities = 79/397 (19%), Positives = 140/397 (35%), Gaps = 38/397 (9%) Query: 68 PNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFY- 126 +LI+LG G + P+ + L Y +G +L ++ + + Sbjct: 55 QGRELINLGQGFFSYSPPQF---AIKEAQKALDIPM-VNQYSPTRGRPSLINSLIKLYSP 110 Query: 127 -RDLHVKSNEVFVSDGAQSDI-SRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHE 184 + +K+ V V+ GA I S L LL + + V +P F YI + + G + Sbjct: 111 IYNTELKAENVTVTTGANEGILSCLMGLLNAGDEVIVFEPFFDQYIPNIELCGGKVVYVP 170 Query: 185 KTKKYQNVVYMPCGPNNSF---FPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFA 241 + G + + A+T +T + +P+NP G V +R++L L + Sbjct: 171 INPPKELDQRNTRGEEWTIDFEQFEKAITSKTKAVIINTPHNPIGKVFTREELTTLGNIC 230 Query: 242 KTNGSIIIFDSAYAAFIEDGSPRSIYEI-PGAREVAIEVSSFSKFAGFTGVRLGWSIIPD 300 + +II D Y S I + P ++ + V S K TG R+GW + + Sbjct: 231 VKHNVVIISDEVYEHLYFTDSFTRIATLSPEIGQLTLTVGSAGKSFAATGWRIGWVLSLN 290 Query: 301 ELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILM 360 L S RI F S + +A + + + + Y KI Sbjct: 291 AELLSYAA---KAHTRI---CFASPSPLQEACANSINDALKIGYFEKMRQEYINKFKIFT 344 Query: 361 DTLVSLGLKVYGGVNAPYLWVHFKG---SKSWDVFNEILENT-------------HIITV 404 LGL ++ V F + + EIL ++ + Sbjct: 345 SIFDELGLPYTAPEGTYFVLVDFSKVKIPEDYPYPEEILNKGKDFRISHWLINELGVVAI 404 Query: 405 PGSGF-----GPGGEEYLRISGFGRRDHIVEASKRLQ 436 P + F E LR + ++ A +RL+ Sbjct: 405 PPTEFYIKEHEKAAENLLRFAVCKDDAYLENAVERLK 441 >2O0R-A nrPDB Length = 411 Score = 224 bits (571), Expect = 6e-59, Method: Composition-based stats. Identities = 82/407 (20%), Positives = 141/407 (34%), Gaps = 39/407 (9%) Query: 48 KNNYLFPEINRRELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRG 107 + L P E + ++LG G E P ++ + G G Sbjct: 3 TVSRLRPYATTVFAEMSALATRIGAVNLGQGFPDEDGPPKMLQAAQDAIAG-----GVNQ 57 Query: 108 YGLEQGNKTLRKAIAETFYRDLHVKSN---EVFVSDGAQSDISRLQL-LLGSNVTIAVQD 163 Y G+ LR+AIA R V + EV V+ GA I+ L L+ + + + Sbjct: 58 YPPGPGSAPLRRAIAAQRRRHFGVDYDPETEVLVTVGATEAIAAAVLGLVEPGSEVLLIE 117 Query: 164 PTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNN 223 P + +Y + G + ++ A+TPRT + SP+N Sbjct: 118 PFYDSYSPVVAMAGAHRVTVPLVPDGRGFAL------DADALRRAVTPRTRALIINSPHN 171 Query: 224 PTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIED-GSPRSIYEIPGAREVAIEVSSF 282 PTG V S +L + + A ++I D Y + D + G E I +SS Sbjct: 172 PTGAVLSATELAAIAEIAVAANLVVITDEVYEHLVFDHARHLPLAGFDGMAERTITISSA 231 Query: 283 SKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGL 342 +K TG ++GW+ P EL+ + + ++ +A Sbjct: 232 AKMFNCTGWKIGWACGPAELIAG-----VRAAKQYLSYVGGAPFQP----AVALALDTED 282 Query: 343 KEIRSVNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFKG---SKSWDVFNEILENT 399 + ++ N + R L L +G V+ +L + S + + E Sbjct: 283 AWVAALRNSLRARRDRLAAGLTEIGFAVHDSYGTYFLCADPRPLGYDDSTEFCAALPEKV 342 Query: 400 HIITVPGSGFGPGGEE-----------YLRISGFGRRDHIVEASKRL 435 + +P S F +R + R D + EA +RL Sbjct: 343 GVAAIPMSAFCDPAAGQASQQADVWNHLVRFTFCKRDDTLDEAIRRL 389 >2DOU-A nrPDB Length = 376 Score = 224 bits (570), Expect = 7e-59, Method: Composition-based stats. Identities = 86/386 (22%), Positives = 152/386 (39%), Gaps = 31/386 (8%) Query: 60 ELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRK 119 E + + V LI L G T P PE + + A L+ Y GY L+ + Sbjct: 15 EAKRKARERGVGLIDLSIGSTDLPPPE---APLKALAEALNDPTTY-GYCLKSCTLPFLE 70 Query: 120 AIAETFYRDLHVKSN---EVFVSDGAQSDISRLQ-LLLGSNVTIAVQDPTFPAYIDSSVI 175 A + V + E G+Q ++ L L + + + +P+Y ++ + Sbjct: 71 EAARWYEGRYGVGLDPRREALALIGSQEGLAHLLLALTEPEDLLLLPEVAYPSYFGAARV 130 Query: 176 IG-QTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQL 234 +T + ++ +P G + V+ PNNPTG VA Sbjct: 131 ASLRTFLIPLREDGLADLKAVPEG----------VWREAKVLLLNYPNNPTGAVADWGYF 180 Query: 235 HQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLG 294 + + A+ +G +I D+ Y + +G S +PGA+E +E+ S SK G RLG Sbjct: 181 EEALGLARKHGLWLIHDNPYVDQVYEGEAPSPLALPGAKERVVELFSLSKSYNLAGFRLG 240 Query: 295 WSIIPDELLYS-NGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYK 353 +++ +E L + DF++ G+ L + + +R Y+ Sbjct: 241 FALGSEEALARLERVKGVIDFNQYAG---------VLRMGVEALKT-PKEVVRGYARVYR 290 Query: 354 ENRKILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSWDVFNEILENTHIITVPGSGFGPGG 413 E + + L + L + YLW F L + PG GFGPGG Sbjct: 291 ERALGMAEALKGV-LSLLPPRATMYLWGRLPEGVDDLEFGLRLVERGVALAPGRGFGPGG 349 Query: 414 EEYLRISGFGRRDHIVEASKRLQNFF 439 + ++RI+ + ++EA+KR++ Sbjct: 350 KGFVRIALVRPLEELLEAAKRIREAL 375 >3T32-A nrPDB Length = 383 Score = 218 bits (554), Expect = 6e-57, Method: Composition-based stats. Identities = 81/402 (20%), Positives = 144/402 (35%), Gaps = 43/402 (10%) Query: 56 INRRELEHIE--KHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQG 113 +NRR I+ + N +LI D +P+ I + + GY L Sbjct: 8 VNRRGTHSIKWDTYKNEELIHAWIADMDFEVPQPIQTALKKRIEHPIF-----GYTLP-- 60 Query: 114 NKTLRKAIAETFYRD--LHVKSNEVFVSDGAQSDIS-RLQLLLGSNVTIAVQDPTFPAYI 170 + + I + ++ + S G +S +Q N ++ VQ P +P + Sbjct: 61 PENIGDIICNWTKKQYNWDIQKEWIVFSAGIVPALSTSIQAFTKENESVLVQPPIYPPFF 120 Query: 171 DSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPR-----TDVIFFCSPNNPT 225 + T Q V N+++ D + ++ CSP+NP Sbjct: 121 EMV-----------TTNNRQLCVSPLQKQNDTYAIDFEHLEKQFQQGVKLMLLCSPHNPI 169 Query: 226 GYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIP--GAREVAIEVSSFS 283 G V +++L +L I++ D ++ I + + I + S Sbjct: 170 GRVWKKEELTKLGSLCTKYNVIVVADEIHSDIIYADHTHTPFASLSEELAARTITCMAPS 229 Query: 284 KFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIV-TTSFNGASNIAQAGGLACLSSGGL 342 K G++ IIP+E L F I F+G NI + + Sbjct: 230 KTFNIAGLQASIIIIPNEKLRQ-------AFTSIQYRQGFHGL-NIFAYTAMQSAYTECN 281 Query: 343 KEIRSVNNYYKENRKILMDTLVS--LGLKVYGGVNAPYLWVHFKGSK-SWDVFNEILENT 399 + + Y ++N K + + L V + LW+ S D ++LE Sbjct: 282 DWLNEIRFYIEDNAKFACEYIKDHIPTLSVMKPEGSFLLWIDCSALNLSQDERTKLLEEK 341 Query: 400 H-IITVPGSGFGPGGEEYLRISGFGRRDHIVEASKRLQNFFN 440 II PG +G GGEE++ I+ R + E RL++ F+ Sbjct: 342 GKIIVEPGEKYGLGGEEHIGINIGCPRSVLEEILNRLRHTFS 383 >3EZS-A nrPDB Length = 376 Score = 217 bits (553), Expect = 8e-57, Method: Composition-based stats. Identities = 89/403 (22%), Positives = 150/403 (37%), Gaps = 53/403 (13%) Query: 51 YLFPEINRRELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGL 110 Y F + E P + + LG G+ P+ I + N H L+ Y Sbjct: 7 YPFERL---RALLKEITPKKRGLDLGIGEPQFETPKFIQDALKNHTHSLNI------YPK 57 Query: 111 EQGNKTLRKAIAETFYRD--LHVKSNEVFVSDGAQSDIS---RLQLLLGSNVTIAVQDPT 165 ++LR A F R + +K NE+ + G++ + L N TIA +P Sbjct: 58 SAFEESLRAAQRGFFKRRFKIELKENELISTLGSREVLFNFPSFVLFDYQNPTIAYPNPF 117 Query: 166 FPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDL--AMTPRTDVIFFCSPNN 223 + Y ++ I + MP N F P L D++ SPNN Sbjct: 118 YQIYEGAAKFIKA------------KSLLMPLTKENDFTPSLNEKELQEVDLVILNSPNN 165 Query: 224 PTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEI-----PGAREVAIE 278 PTG S ++L V A + I+I D Y+ E+ P S+ E A + + Sbjct: 166 PTGRTLSLEELISWVKLALKHDFILINDECYSEIYENTPPPSLLEACMLAGNEAFKNVLV 225 Query: 279 VSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLS 338 + S SK + G+R G+ LL F + + A+ I +A A L Sbjct: 226 IHSLSKRSSAPGLRSGFIAGDSRLLEK-----YKAFRAYLG--YTSANAIQKASEAAWLD 278 Query: 339 SGGLKEIRSV-NNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSWDVFNEILE 397 + R++ N K RKI +TL+ +V+ + + + Sbjct: 279 DRHAEFFRNIYANNLKLARKIFKNTLIYP----------YSFYVYLPVQNGENFAKTLYQ 328 Query: 398 NTHIITVPGSGFGPG--GEEYLRISGFGRRDHIVEASKRLQNF 438 N IIT+P G G +Y+R++ + + + ++ + Sbjct: 329 NEGIITLPALYLGRNRIGADYVRLALVYDTPLLEKPLEIIETY 371 >3FDB-A nrPDB Length = 377 Score = 213 bits (542), Expect = 1e-55, Method: Composition-based stats. Identities = 70/403 (17%), Positives = 133/403 (33%), Gaps = 41/403 (10%) Query: 50 NYLFPEIN--RRELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRG 107 FP I R ++ L ++ + +++ + G Sbjct: 1 GMQFPSIEDLRARNTMKWTRYGQGVLPLWVAESDFSTCPAVLQAITDAVQREAF-----G 55 Query: 108 YGLEQGNKTLRKAIAETFYRDLHVK--SNEVF-VSDGAQSDISRLQLLLGSNVTIAVQDP 164 Y + L +A AE + + +F + D + + + + V P Sbjct: 56 YQPDGSL--LSQATAEFYADRYGYQARPEWIFPIPDVVRGLYIAIDHFTPAQSKVIVPTP 113 Query: 165 TFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNP 224 +P + + G F + T N + I C+P NP Sbjct: 114 AYPPFFHLLSATQREGIFIDATGGI-----------NLHDVEKGFQAGARSILLCNPYNP 162 Query: 225 TGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPG-AREVAIEVSSFS 283 G V + + L++L D A + ++ D +A + DG + A V I +++ S Sbjct: 163 LGMVFAPEWLNELCDLAHRYDARVLVDEIHAPLVFDGQHTVAAGVSDTAASVCITITAPS 222 Query: 284 KFAGFTGVR---LGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSG 340 K G++ + +S D + P+I D GAS + A Sbjct: 223 KAWNIAGLKCAQIIFSNPSDAEHWQQLSPVIKD----------GASTLGLIAAEAAYRY- 271 Query: 341 GLKEIRSVNNYYKENRKILMDTLVS--LGLKVYGGVNAPYLWVHFKGSKSWDVFNEIL-E 397 G + Y K N L+ + G K+ +W+ F+ + +E E Sbjct: 272 GTDFLNQEVAYLKNNHDFLLHEIPKRIPGAKITPMQATYLMWIDFRDTTIEGSPSEFFIE 331 Query: 398 NTHIITVPGSGFGPGGEEYLRISGFGRRDHIVEASKRLQNFFN 440 + G+ FG G + R++ R+ + EA R+ + Sbjct: 332 KAKVAMNDGAWFGEDGTGFCRLNFATSREVLEEAIDRMAKAVS 374 >3B1C-A nrPDB Length = 392 Score = 212 bits (539), Expect = 3e-55, Method: Composition-based stats. Identities = 63/392 (16%), Positives = 139/392 (35%), Gaps = 32/392 (8%) Query: 55 EINRRELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGN 114 ++ + E + QL+ D + ++ + ++A L YG + Sbjct: 16 RLSHHTYKWKETETDPQLLPAWIADMDFEVMPEVKQAIHDYAEQLV-------YGYTYAS 68 Query: 115 KTLRKAIAETFY--RDLHVKSNEVFVSDGAQSDIS-RLQLLLGSNVTIAVQDPTFPAYID 171 L +A+ + ++ +G IS +Q + + P +P + Sbjct: 69 DELLQAVLDWEKSEHQYSFDKEDIVFVEGVVPAISIAIQAFTKEGEAVLINSPVYPPFAR 128 Query: 172 SSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASR 231 S + + + ++ N + + C+P+NP G V R Sbjct: 129 SVRLNNRKLVSNSLKEENGLFQIDFEQLENDIVEN-----DVKLYLLCNPHNPGGRVWER 183 Query: 232 KQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYE--IPGAREVAIEVSSFSKFAGFT 289 + L Q+ + + I++ D + G + P ++ A+ +SS +K Sbjct: 184 EVLEQIGHLCQKHHVILVSDEIHQDLTLFGHEHVSFNTVSPDFKDFALVLSSATKTFNIA 243 Query: 290 GVRLGWSIIPDELLYSN--GFPIINDFHRIVTTSFNGASNIAQAGG--LACLSSGGLKEI 345 G + ++II + L + ++N+ H + + + + G L L + + I Sbjct: 244 GTKNSYAIIENPTLCAQFKHQQLVNNHHEVSSLGYIATETAYRYGKPWLVALKAVLEENI 303 Query: 346 RSVNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFK--GSKSWDVFNEILENTHIIT 403 + Y+ + + LKV +W+ F G +F + + +I Sbjct: 304 QFAVEYFAQ---------EAPRLKVMKPQGTYLIWLDFSDYGLTDDALFTLLHDQAKVIL 354 Query: 404 VPGSGFGPGGEEYLRISGFGRRDHIVEASKRL 435 GS +G GE + R++ + + E KR+ Sbjct: 355 NRGSDYGSEGELHARLNIAAPKSLVEEICKRI 386 >2GB3-A nrPDB Length = 409 Score = 209 bits (532), Expect = 2e-54, Method: Composition-based stats. Identities = 82/412 (19%), Positives = 148/412 (35%), Gaps = 49/412 (11%) Query: 47 LKNNYLFPEINRRELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYR 106 ++ F E+ ++ V++ L G PE + + E Sbjct: 28 IRKLVPFAEMAKKR--------GVRIHHLNIGQPDLKTPEVFFERIYE-----NKPE-VV 73 Query: 107 GYGLEQGNKTLRKAIAETFYRD--LHVKSNEVFVSDGAQSDI-SRLQLLLGSNVTIAVQD 163 Y G LR+A A + R + VK V V++G I ++ I V + Sbjct: 74 YYSHSAGIWELREAFASYYKRRQRVDVKPENVLVTNGGSEAILFSFAVIANPGDEILVLE 133 Query: 164 PTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNN 223 P + Y + I G T++ + +P + + RT I +P N Sbjct: 134 PFYANYNAFAKIAGVK--LIPVTRRMEEGFAIPQNLESF------INERTKGIVLSNPCN 185 Query: 224 PTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFS 283 PTG V + ++ LV+ A+ +G +I D Y+ + G S I + + + S S Sbjct: 186 PTGVVYGKDEMRYLVEIAERHGLFLIVDEVYSEIVFRGEFASALSI--ESDKVVVIDSVS 243 Query: 284 KFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLK 343 K G R+G I +E L S + + Q G + L+ Sbjct: 244 KKFSACGARVGCLITRNEELIS--------HAMKLAQGRLAPPLLEQIGSVGLLNLDD-S 294 Query: 344 EIRSVNNYYKENRKILMDTLVSLGLK-VYGGVNAPYLWVHFKGSKSWDVFNEILENTHI- 401 V Y+E + ++ L GLK A Y+ + + +L + ++ Sbjct: 295 FFDFVRETYRERVETVLKKLEEHGLKRFTKPSGAFYITAELPVEDAEEFARWMLTDFNMD 354 Query: 402 ----ITVPGSGFGPG---GEEYLRISGFGRRDHIVEA----SKRLQNFFNTR 442 + P GF G++ +RI+ +D + A + L+ F ++R Sbjct: 355 GETTMVAPLRGFYLTPGLGKKEIRIACVLEKDLLSRAIDVLMEGLKMFCSSR 406 >3DZZ-A nrPDB Length = 391 Score = 206 bits (523), Expect = 2e-53, Method: Composition-based stats. Identities = 77/407 (18%), Positives = 148/407 (36%), Gaps = 43/407 (10%) Query: 48 KNNYLFPEINRRELEHIEKHP-NVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYR 106 + Y F + +R+ I+ + + + + I +I + M + Sbjct: 4 EKQYDFTHVPKRQGNSIKWGVLKEKELPMWIAEMDFKIAPEIMASMEEKLKVAA------ 57 Query: 107 GYGLEQGNKTLRKAIAET--FYRDLHVKSNEVFVSDGAQSDISRLQL-LLGSNVTIAVQD 163 +G E KA+A+ K + + G IS + I VQ+ Sbjct: 58 -FGYESVPAEYYKAVADWEEIEHRARPKEDWCVFASGVVPAISAMVRQFTSPGDQILVQE 116 Query: 164 PTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNN 223 P + + SVI G Y+N Y N + + TP ++ FC+P+N Sbjct: 117 PVYNMFY--SVIEGNGRRVISSDLIYENSKY---SVNWADLEEKLATPSVRMMVFCNPHN 171 Query: 224 PTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFI---EDGSPRSIYEIPGAREVAIEVS 280 P GY S +++ ++ + + ++I D + + ED +P + A+ + + Sbjct: 172 PIGYAWSEEEVKRIAELCAKHQVLLISDEIHGDLVLTDEDITPAFTVDW-DAKNWVVSLI 230 Query: 281 SFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSF----NGASNIAQAGGLAC 336 S SK + +IIP+ D SF G N+ Sbjct: 231 SPSKTFNLAALHAACAIIPNP-----------DLRARAEESFFLAGIGEPNLLAIPAAIA 279 Query: 337 LSSGGLKEIRSVNNYYKEN----RKILMDTLVSLGLKVYGGVNAPYLWVHFK--GSKSWD 390 G +R + ++N R+ L + +KV + WV G + D Sbjct: 280 AYEEGHDWLRELKQVLRDNFAYAREFLAKEVPE--VKVLDSNASYLAWVDISALGMNAED 337 Query: 391 VFNEILENTHIITVPGSGFGPGGEEYLRISGFGRRDHIVEASKRLQN 437 + E T +I G+G+ G E++RI+ ++ +++ +RL+ Sbjct: 338 FCKYLREKTGLIISAGNGYRGNGHEFVRINLACPKELVIDGMQRLKQ 384 >1WST-A nrPDB Length = 417 Score = 204 bits (519), Expect = 6e-53, Method: Composition-based stats. Identities = 72/408 (17%), Positives = 129/408 (31%), Gaps = 26/408 (6%) Query: 48 KNNYLFPEINRRELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRG 107 + L REL + + +V ++ G E I + Sbjct: 21 EKAMLMKASEVRELLKLVETSDVISLAGGLPAPETFPVETIKKIAVEVLEEHADK--ALQ 78 Query: 108 YGLEQGNKTLRKAIAETFYRDLHVKSN--EVFVSDGAQSDISRL-QLLLGSNVTIAVQDP 164 YG +G LR A+A + + + E+ G+Q + + ++ L I V+ P Sbjct: 79 YGTTKGFTPLRLALARWMEKRYDIPMSKVEIMTVAGSQQALDLIGRVFLNPGDPIVVEAP 138 Query: 165 TFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIF-FCSPNN 223 T+ A I + K V R +++ + N Sbjct: 139 TYLAAIQAFKYYDPEFISIPLDDKGMRV----DLLEEKLEELRKQGKRVKIVYTVSTFQN 194 Query: 224 PTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFS 283 P G S + +L++ A +I+ D Y+ G P + I + +FS Sbjct: 195 PAGVTMSVDRRKKLLELANEYDFLIVEDGPYSELRYSGEPTPPIKHFDDYGRVIYLGTFS 254 Query: 284 KFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLK 343 K G R+GW L I + + QA + +G L Sbjct: 255 KILA-PGFRIGWVAAHPHL--------IRKMEIAKQSIDLCTNTFGQAIAWKYVENGYLD 305 Query: 344 E-IRSVNNYYKENRKILMDTLVS---LGLKVYGGVNAPYLWVHFKGSKSWDVFNEILENT 399 E I + +YK R +++ L G++ ++ V + E Sbjct: 306 EHIPKIIEFYKPRRDAMLEALEEYMPEGVEWTKPEGGMFVRVTLPEGIDTKLMMERAVAK 365 Query: 400 HIITVPGSGF--GPGGEEYLRISGF-GRRDHIVEASKRLQNFFNTRTK 444 + VPG F + +R++ + I E +RL K Sbjct: 366 GVAYVPGEAFFVHRDKKNTMRLNFTYVPEETIREGVRRLAETIKEEMK 413 >2ZYJ-A nrPDB Length = 397 Score = 202 bits (513), Expect = 3e-52, Method: Composition-based stats. Identities = 81/398 (20%), Positives = 147/398 (36%), Gaps = 45/398 (11%) Query: 59 RELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEG---YRGYGLEQGNK 115 REL + + P ++S G P PE + A E Y +G Sbjct: 23 RELLKLTQRPG--ILSFAGG---LPAPELFPKEEAAEAAARILREKGEVALQYSPTEGYA 77 Query: 116 TLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRL-QLLLGSNVTIAVQDPTFPAYIDSSV 174 LR +AE + V+ EV ++ G+Q + + ++ L + ++ P++ Sbjct: 78 PLRAFVAEW----IGVRPEEVLITTGSQQALDLVGKVFLDEGSPVLLEAPSY-------- 125 Query: 175 IIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFC-SPNNPTGYVASRKQ 233 +G F + ++ V GP+ ++ R ++ S NPTG + Sbjct: 126 -MGAIQAFRLQGPRFLTVPAGEEGPDLDALEEVLKRERPRFLYLIPSFQNPTGGLTPLPA 184 Query: 234 LHQLVDFAKTNGSIIIFDSAYAAFIE-DGSPRSIYEIP--GAREVAIEVSSFSKFAGFTG 290 +L+ G +++ D AY + S++E+ I + SFSK G Sbjct: 185 RKRLLQMVMERGLVVVEDDAYRELYFGEARLPSLFELAREAGYPGVIYLGSFSKVLS-PG 243 Query: 291 VRLGWSII-PDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVN 349 +R+ +++ P+ L D H + Q L G + + V Sbjct: 244 LRVAFAVAHPEALQKLVQAKQGADLH---------TPMLNQMLVHELLKEGFSERLERVR 294 Query: 350 NYYKENRKILMDTL---VSLGLKVYGGVNAPYLWVHFK-GSKSWDVFNEILENTHIITVP 405 Y+E + ++ L V ++ ++W+ G + +F LE ++ VP Sbjct: 295 RVYREKAQAMLHALDREVPKEVRYTRPKGGMFVWMELPKGLSAEGLFRRALEE-NVAFVP 353 Query: 406 GSGF--GPGGEEYLRISGFG-RRDHIVEASKRLQNFFN 440 G F GGE LR+S R+ I E +RL Sbjct: 354 GGPFFANGGGENTLRLSYATLDREGIAEGVRRLGRALK 391 >1M4N-A nrPDB Length = 435 Score = 199 bits (505), Expect = 2e-51, Method: Composition-based stats. Identities = 64/379 (16%), Positives = 124/379 (32%), Gaps = 34/379 (8%) Query: 89 TSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYR----DLHVKSNEVFVSDGAQ- 143 + +G S + G +KA+ + + N + ++ GA Sbjct: 63 PEAAAFKKNGESIFAELALFQDYHGLPAFKKAMVDFMAEIRGNKVTFDPNHLVLTAGATS 122 Query: 144 SDISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSF 203 ++ + + L + + P +P + ++ Sbjct: 123 ANETFIFCLADPGEAVLIPTPYYPGFDRDLKWRTGVEIVPIHCTSSNGFQITETALEEAY 182 Query: 204 FPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDG-- 261 R + +P+NP G +R +L+ L+ F + G +I D Y+ Sbjct: 183 QEAEKRNLRVKGVLVTNPSNPLGTTMTRNELYLLLSFVEDKGIHLISDEIYSGTAFSSPS 242 Query: 262 --------SPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIIND 313 R+ E + V S SK G G R+G +YSN ++ Sbjct: 243 FISVMEVLKDRNCDENSEVWQRVHVVYSLSKDLGLPGFRVG-------AIYSNDDMVVAA 295 Query: 314 FHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNY--YKENRKILMDTLVSLGLKVY 371 ++ SF S+ Q A LS L + N+ K+ +K L+ L G+ Sbjct: 296 ATKMS--SFGLVSSQTQHLLSAMLSDKKLTKNYIAENHKRLKQRQKKLVSGLQKSGISCL 353 Query: 372 GGVNAPYLWVHFKG-------SKSWDVFNEILENTHIITVPGSGFGPGGEEYLRISGFGR 424 G + WV + +++ +I+ H+ PGS + R+ Sbjct: 354 NGNAGLFCWVDMRHLLRSNTFEAEMELWKKIVYEVHLNISPGSSCHCTEPGWFRVCFANL 413 Query: 425 RDHIVE-ASKRLQNFFNTR 442 + ++ A +RL+ F Sbjct: 414 PERTLDLAMQRLKAFVGEY 432 >2ZC0-A nrPDB Length = 407 Score = 197 bits (501), Expect = 8e-51, Method: Composition-based stats. Identities = 75/411 (18%), Positives = 144/411 (35%), Gaps = 32/411 (7%) Query: 49 NNYLFPEINRRELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRG- 107 ++ ++ E +K V+LISL GD PE I + + + Sbjct: 15 KGSALADVMKKASELQKK--GVKLISLAAGDPD---PELIPRAVLGEIAKEVLEKEPKSV 69 Query: 108 -YGLEQGNKTLRKAIAETFYRDLHVK--SNEVFVSDGAQSDISRL-QLLLGSNVTIAVQD 163 Y G LR+ +A + H++ + ++ G + L ++L+ + ++ Sbjct: 70 MYTPANGIPELREELAAFLKKYDHLEVSPENIVITIGGTGALDLLGRVLIDPGDVVITEN 129 Query: 164 PTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIF-FCSPN 222 P++ + + +G V + A + +I+ + Sbjct: 130 PSYINTLLAFEQLGAKIEGVPVDNDGMRVDLL----EEKIKELKAKGQKVKLIYTIPTGQ 185 Query: 223 NPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSF 282 NP G S ++ L++ A +II D+AY +G + I + Sbjct: 186 NPMGVTMSMERRKALLEIASKYDLLIIEDTAYNFMRYEGGDIVPLKALDNEGRVIVAGTL 245 Query: 283 SKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGL 342 SK G TG R+GW I E I+ A I+Q L L G Sbjct: 246 SKVLG-TGFRIGWIIAEGE--------ILKKVLMQKQPIDFCAPAISQYIALEYLKRGYF 296 Query: 343 K--EIRSVNNYYKENRKILMDTLVS--LGLKVYGGVNAPYLWVHFK-GSKSWDVFNEILE 397 + + YKE R I++ L + + + ++ G+ NE++E Sbjct: 297 EKYHLEGALLGYKEKRDIMLKALENHLPNAEFTKPIAGMFVMFFLPEGADGISFANELME 356 Query: 398 NTHIITVPGSGF--GPGGEEYLRISGFGR-RDHIVEASKRLQNFFNTRTKH 445 ++ VPG F G+ +R++ ++ I K+L + + Sbjct: 357 REGVVVVPGKPFYTDESGKNAIRLNFSRPSKEEIPIGIKKLAKLYKEKFGE 407 >2HOR-A nrPDB Length = 427 Score = 189 bits (481), Expect = 2e-48, Method: Composition-based stats. Identities = 79/377 (20%), Positives = 135/377 (35%), Gaps = 52/377 (13%) Query: 88 ITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDIS 147 + S ++ + V + + LE+ K L + + +D + + G I Sbjct: 83 LVSPWHRMSYFFNPVSNFISFELEKTIKELHEVVGNAAAKDRY-----IVFGVGVTQLIH 137 Query: 148 RLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGH--FHEKTKKYQNVVYMPCGPNNSFFP 205 L + L N+T P +S V+ + F E+TK + Y+ G ++ Sbjct: 138 GLVISLSPNMTATPDAP------ESKVVAHAPFYPVFREQTKYFDKKGYVWAGNAANYVN 191 Query: 206 DLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRS 265 P + SPNNP G L+ A G I+D Y + +P Sbjct: 192 VS--NPEQYIEMVTSPNNPEG----------LLRHAVIKGCKSIYDMVY--YWPHYTP-- 235 Query: 266 IYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSN----------GFPIINDFH 315 I + I + + SKF G +G R GW++I DE +Y+N G P Sbjct: 236 ---IKYKADEDILLFTMSKFTGHSGSRFGWALIKDESVYNNLLNYMTKNTEGTPRETQLR 292 Query: 316 RIVTTSFNGASNIAQAGGLACLSSGGLKEIRS----VNNYYKENRKILMDTLVSLGLKVY 371 + A Q G + L++ G K++R + ++ + L Y Sbjct: 293 SLKVLKEVVAMVKTQKGTMRDLNTFGFKKLRERWVNITALLDQSDRFSYQELPQSEYCNY 352 Query: 372 GGVNAP----YLWVHFKGSKSWDVFNEILENTHIITVPGSGFGPGGEEYLRISGFGRRDH 427 P Y WV + + D + +N I T G GF Y+R+S +D Sbjct: 353 FRRMRPPSPSYAWVKCEWEEDKD-CYQTFQNGRINTQNGVGF-EASSRYVRLSLIKTQDD 410 Query: 428 IVEASKRLQNFFNTRTK 444 + L++ + K Sbjct: 411 FDQLMYYLKDMVKAKRK 427 >5Z0Q-C nrPDB Length = 389 Score = 186 bits (473), Expect = 1e-47, Method: Composition-based stats. Identities = 66/396 (16%), Positives = 140/396 (35%), Gaps = 33/396 (8%) Query: 55 EINRRELEHIE--KHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQ 112 I+RR + ++ K+ + ++ L DT + I + +G GYG+ Sbjct: 16 RIDRRHSDSLKWKKYADRDILPLWIADTDFRAADCIIDALQQRVQ-----QGVFGYGVTS 70 Query: 113 GNKTLRKAIAETFYR--DLHVKSNEVFVSDGAQSDIS-RLQLLLGSNVTIAVQDPTFPAY 169 + L + E ++ + G + I+ ++ ++ + P +P + Sbjct: 71 --EALAEVAIERMESRFGWKIQPEWLVFLPGVVTGINIAVRAFTEAHQSTVSATPIYPPF 128 Query: 170 IDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVA 229 + + G+ + Q V + M+ ++ C+P+NP G V Sbjct: 129 FLAPKLAGRQHLSAALRLEQQRWVLDLDSHEDR------MSGNEKLLLLCNPHNPGGTVY 182 Query: 230 SRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDG---SPRSIYEIPGAREVAIEVSSFSKFA 286 RK+L + FA+ + ++ D + + + A + +I + S SK Sbjct: 183 RRKELEAQLRFAQRHDLLVCSDEIHCDLVLEPGVQHIPFASLSDDAAQRSITLMSPSKSF 242 Query: 287 GFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIR 346 G+ ++IP+ L + F+R+ +A A G + Sbjct: 243 NIAGLGASLAVIPNPELRA-------RFNRMRKGMVPDVDVLAYVAASAAWR-EGQPWLD 294 Query: 347 SVNNYYKENRKILMDTLVS-LGLKVYGGVNAPYLWVHFKGSKSWDVFNEILENTHIITVP 405 + +Y + NR +L + GL + + W+ G D E + Sbjct: 295 AQLDYLRANRDMLAQHVNRLPGLSMVTPEASFLGWIDASGLGVAD-PALFFEKHGLGFSS 353 Query: 406 GSGFGPGGEEYLRISGFGRRDHIVEASKRLQNFFNT 441 G FG + ++R + R + EA +R+ + Sbjct: 354 GRDFGN--DRFVRFNFGCPRQLLEEALQRMTRALTS 387 >3L8A-A nrPDB Length = 421 Score = 182 bits (461), Expect = 3e-46, Method: Composition-based stats. Identities = 67/430 (15%), Positives = 148/430 (34%), Gaps = 31/430 (7%) Query: 20 IPKASLDFEMKKLGGSTKLVRNVNLEKLKNNYLFPEINRRELEHIEKHPNVQLISLGTGD 79 +P+ S M + G ++ R + + +N+ + N +L+ + D Sbjct: 15 VPRGS---HMASMTGGQQMGRGS-MGRYDFTTRPDRLNQFTYKWKTSENNPELLQMWVAD 70 Query: 80 TTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYR--DLHVKSNEVF 137 +I + N +G N L +A+ + + D V ++ Sbjct: 71 MDFLPVPEIKEAIIN-------YGREHIFGYNYFNDDLYQAVIDWERKEHDYAVVKEDIL 123 Query: 138 VSDGAQSDIS-RLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMP 196 DG IS LQ + + P + + + + + H + ++ Sbjct: 124 FIDGVVPAISIALQAFSEKGDAVLINSPVYYPFARTIRL-----NDHRLVENSLQIINGR 178 Query: 197 CGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAA 256 + + + CSP+NP G V L ++ + K +G I++ D + Sbjct: 179 FEIDFEQLEKDIIDNNVKIYLLCSPHNPGGRVWDNDDLIKIAELCKKHGVILVSDEIHQD 238 Query: 257 FIEDGSPRSIYEIPGA--REVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDF 314 G+ A ++ I +SS +K G + ++II +E L Sbjct: 239 LALFGNTHHSLNTLDASYKDFTIILSSATKTFNIAGTKNSFAIIQNESLRRKFQ------ 292 Query: 315 HRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILMDTLV-SLGLKVYGG 373 +R + + + + A G + + + N K+++ L +KV Sbjct: 293 YRQLANNQHEVPTVGMIATQAAFQYGKP-WLEELKTVIEGNIKLVIKELEAKTKIKVMEP 351 Query: 374 VNAPYLWVHFKGSKSW--DVFNEILENTHIITVPGSGFGPGGEEYLRISGFGRRDHIVEA 431 +W+ F + ++ ++ G+ FG G+ + R++ ++ + EA Sbjct: 352 EGTYLVWLDFSAYAIAQPQLSEKLQNEAKVVLNDGAHFGKEGKYFARLNVATPKNTVQEA 411 Query: 432 SKRLQNFFNT 441 R+ + F Sbjct: 412 LSRIISVFGK 421 >1IAY-A nrPDB Length = 428 Score = 182 bits (461), Expect = 4e-46, Method: Composition-based stats. Identities = 65/370 (17%), Positives = 118/370 (31%), Gaps = 35/370 (9%) Query: 93 SNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYRDLH----VKSNEVFVSDGAQSD-IS 147 S + ++ Y G RKAIA+ + V ++ GA + Sbjct: 67 SEGIKSFKAIANFQDY---HGLPEFRKAIAKFMEKTRGGRVRFDPERVVMAGGATGANET 123 Query: 148 RLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDL 207 + L V P +PA+ + N ++ Sbjct: 124 IIFCLADPGDAFLVPSPYYPAFNRDLRWRTGVQLIPIHCESSNNFKITSKAVKEAYENAQ 183 Query: 208 AMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIED-GSPRSI 266 + + +P+NP G + L ++ F + ++ D YAA + D SI Sbjct: 184 KSNIKVKGLILTNPSNPLGTTLDKDTLKSVLSFTNQHNIHLVCDEIYAATVFDTPQFVSI 243 Query: 267 YEIPG-------AREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVT 319 EI +++ V S SK G G R+G ++YS ++N ++ Sbjct: 244 AEILDEQEMTYCNKDLVHIVYSLSKDMGLPGFRVG-------IIYSFNDDVVNCARKMS- 295 Query: 320 TSFNGASNIAQAGGLACLSSGGL--KEIRSVNNYYKENRKILMDTLVSLGLKVYGGVNAP 377 SF S Q A LS +R + K + L +G+K Sbjct: 296 -SFGLVSTQTQYFLAAMLSDEKFVDNFLRESAMRLGKRHKHFTNGLEVVGIKCLKNNAGL 354 Query: 378 YLWVHFKG-------SKSWDVFNEILENTHIITVPGSGFGPGGEEYLRISGFG-RRDHIV 429 + W+ + ++ I+ + + PGS F + R+ + Sbjct: 355 FCWMDLRPLLRESTFDSEMSLWRVIINDVKLNVSPGSSFECQEPGWFRVCFANMDDGTVD 414 Query: 430 EASKRLQNFF 439 A R++ F Sbjct: 415 IALARIRRFV 424 >4M2J-A nrPDB Length = 406 Score = 181 bits (458), Expect = 8e-46, Method: Composition-based stats. Identities = 67/349 (19%), Positives = 125/349 (35%), Gaps = 42/349 (12%) Query: 109 GLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISR-LQLLLGSNVTIAVQDPTFP 167 + QG + +R+AIA+ + ++ V V+ G+ I+ L LL + VQ+ + Sbjct: 81 SVSQGGEGVRRAIADRYAGG---DADRVLVTHGSSEAIALTLNALLHRGDRVVVQEGIYH 137 Query: 168 AYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLA---MTPRTDVIFFCSPNNP 224 + GH+ V+ + PD+ +TP T + P+NP Sbjct: 138 SL----------GHYPRAAGCDVAVLPGRAVRDGEIDPDVLAGLVTPGTAAVIVNFPHNP 187 Query: 225 TGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAR-EVAIEVSSFS 283 TG S + L L + G+++++D+A A + PGA + + S Sbjct: 188 TGVTLSPQGLRALKERTAATGAVLVWDAATAEI---AHRWEVLADPGADGGDTVSYGTLS 244 Query: 284 KFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLK 343 K G G+R+GW++ P ELL + + + S + + + + Sbjct: 245 KTFGLPGLRVGWAVAPKELLTATFP--------LRDRTTLFLSPLVELVAERAVRHAD-E 295 Query: 344 EIRSVNNYYKENRKILMDTLVSLG--LKVYGGVNAPYLWVHFK--------GSKSWDVFN 393 I + + N L + + ++ F+ + Sbjct: 296 LIGARAAEARHNLAHLTGWMAAHEELVRWTPPEGGVCALPVFRELERAAAGPQEVERFCL 355 Query: 394 EILENTHIITVPGSGFGPGGEEYLRISGFGRRDHIVEASKRLQNFFNTR 442 E+LE + VPG+ FG R+ G ++ L F R Sbjct: 356 ELLERHRTLLVPGTAFGA--PHGARLGFGGPQEDFRAGLDGLSRFLRER 402 >1VP4-A nrPDB Length = 425 Score = 178 bits (450), Expect = 6e-45, Method: Composition-based stats. Identities = 66/400 (16%), Positives = 130/400 (32%), Gaps = 43/400 (10%) Query: 69 NVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYR--GYGLEQGNKTLRKAIAETFY 126 + IS G G ++ A + E + Y +G+ L++ I + Sbjct: 42 DKDAISFGGGVPDPET--FPRKELAEIAKEIIEKEYHYTLQYSTTEGDPVLKQQILKLLE 99 Query: 127 RDLHV---KSNEVFVSDGAQSDISRL-QLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHF 182 R + + + + G+Q + + +L L + DP + +G F Sbjct: 100 RMYGITGLDEDNLIFTVGSQQALDLIGKLFLDDESYCVLDDPAY---------LGAINAF 150 Query: 183 HEKTKKYQNVVYMPCGPN----NSFFPDLAMTPRTDVI----FFCSPNNPTGYVASRKQL 234 + + V G + + + + + +NP G S ++ Sbjct: 151 RQYLANFVVVPLEDDGMDLNVLERKLSEFDKNGKIKQVKFIYVVSNFHNPAGVTTSLEKR 210 Query: 235 HQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLG 294 LV+ A+ I+ D Y A +G G E + +++FSK G+R+G Sbjct: 211 KALVEIAEKYDLFIVEDDPYGALRYEGETVDPIFKIGGPERVVLLNTFSKVLA-PGLRIG 269 Query: 295 WSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGG-LKEIRSVNNYYK 353 E I + ++ + I L L++++ Y+ Sbjct: 270 MVAGSKEF--------IRKIVQAKQSADLCSPAITHRLAARYLERYDLLEQLKPTIELYR 321 Query: 354 ENRKILMDTLVS-----LGLKVYGGVNAPYLWVHFKGSKSWDVFNEILENTHIITVPGSG 408 R ++++ L G+K ++W+ E + + VPG Sbjct: 322 RKRTVMLNALEEYFSDIPGVKWVKSEGGLFIWLTLPEGFDTWEMFEYAKRKKVFYVPGRV 381 Query: 409 FG--PGGEEYLRISGFGRR-DHIVEASKRLQNFFNTRTKH 445 F +R+S + IVE KRL+ K Sbjct: 382 FKVYDEPSPSMRLSFCLPPDEKIVEGIKRLREVVLEYGKE 421 >1C7O-A nrPDB Length = 399 Score = 163 bits (413), Expect = 1e-40, Method: Composition-based stats. Identities = 62/416 (14%), Positives = 132/416 (31%), Gaps = 38/416 (9%) Query: 34 GSTKLVRNVNLEKLKNNYLFPEINRRELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMS 93 +TK+ R NL LK + ++ + +++ L D P ++ + Sbjct: 5 FTTKISR-KNLGSLKWDLMYSQ---------NPEVGNEVVPLSVADMEFKNPPELIEGLK 54 Query: 94 NFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFY--RDLHVKSNEVFVSDGAQSD-ISRLQ 150 + E GY + +K + + ++++ + + G + ++ Sbjct: 55 KYL-----DETVLGYTGP--TEEYKKTVKKWMKDRHQWDIQTDWIINTAGVVPAVFNAVR 107 Query: 151 LLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMT 210 + + P + Y I Q E ++ Y + L+ Sbjct: 108 EFTKPGDGVIIITPVY--YPFFMAIKNQERKIIECELLEKDGYY---TIDFQKLEKLSKD 162 Query: 211 PRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIP 270 + FCSP+NP G V + +L ++ D + ++ D + I G ++++ Sbjct: 163 KNNKALLFCSPHNPVGRVWKKDELQKIKDIVLKSDLMLWSDEIHFDLIMPGYEHTVFQSI 222 Query: 271 GA--REVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNI 328 + I ++ SK G+ + II + + F + + Sbjct: 223 DEQLADKTITFTAPSKTFNIAGMGMSNIIIKNPDIR-------ERFTKSRDATSGMPFTT 275 Query: 329 AQAGGLACLSSGGLKEIRSVNNYYKENRKILMD--TLVSLGLKVYGGVNAPYLWVHFKG- 385 K + +N++I+ D + +K W+ F+ Sbjct: 276 LGYKACEICYKECGKWLDGCIKVIDKNQRIVKDFFEVNHPEIKAPLIEGTYLQWIDFRAL 335 Query: 386 SKSWDVFNEI-LENTHIITVPGSGFGPGGEEYLRISGFGRRDHIVEASKRLQNFFN 440 E + I G FG GG + RI+ I E+ +RL Sbjct: 336 KMDHKAMEEFMIHKAQIFFDEGYIFGDGGIGFERINLAAPSSVIQESLERLNKALK 391 >1D2F-A nrPDB Length = 390 Score = 157 bits (397), Expect = 9e-39, Method: Composition-based stats. Identities = 60/384 (15%), Positives = 122/384 (31%), Gaps = 25/384 (6%) Query: 65 EKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAET 124 ++ L+ D I ++ G GY + N AIA Sbjct: 23 DRFGTADLLPFTISDMDFATAPCIIEALNQRLMH-----GVFGYSRWK-NDEFLAAIAHW 76 Query: 125 FYRDLHVKSNEVFVSDGAQSDISRLQLLL---GSNVTIAVQDPTFPAYIDSSVIIGQTGH 181 F + + V G +L+ + + + P + A+ + I G Sbjct: 77 FSTQHYTAIDSQTVVYGPSVIYMVSELIRQWSETGEGVVIHTPAYDAFYKA--IEGNQRT 134 Query: 182 FHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFA 241 + Q + + + P ++ CSP NPTG V + +L + D Sbjct: 135 VMPVALEKQADGWFC---DMGKLEAVLAKPECKIMLLCSPQNPTGKVWTCDELEIMADLC 191 Query: 242 KTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDE 301 + +G +I D + + P + + A+ S SK + + II + Sbjct: 192 ERHGVRVISDEIHMDMVWGEQPHIPWSNVARGDWALLTSG-SKSFNIPALTGAYGIIENS 250 Query: 302 LLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILMD 361 + + S +A +A G + ++ Y K+N + D Sbjct: 251 SSRDAYLSALKG-----RDGLSSPSVLALTAHIAAYQQGAP-WLDALRIYLKDNLTYIAD 304 Query: 362 TLVS--LGLKVYGGVNAPYLWVHFKGSKSWDVFNE--ILENTHIITVPGSGFGPGGEEYL 417 + + L + W+ + D + ++E + +PG +G G ++ Sbjct: 305 KMNAAFPELNWQIPQSTYLAWLDLRPLNIDDNALQKALIEQEKVAIMPGYTYGEEGRGFV 364 Query: 418 RISGFGRRDHIVEASKRLQNFFNT 441 R++ R + + L N Sbjct: 365 RLNAGCPRSKLEKGVAGLINAIRA 388 >4R2N-A nrPDB Length = 367 Score = 151 bits (381), Expect = 7e-37, Method: Composition-based stats. Identities = 74/398 (18%), Positives = 139/398 (34%), Gaps = 47/398 (11%) Query: 51 YLFPEINRRELEHIEKHPNVQL---ISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRG 107 + + P + I L + +T + + + ++ Sbjct: 1 MVTARLRPELAGLPVYVPGKTVPGAIKLASNETVFGPLPSVRAAIDRATDTVNRY----- 55 Query: 108 YGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRL-QLLLGSNVTIAVQDPTF 166 + G L+ A+A D V V G+ S +L Q+ + +F Sbjct: 56 --PDNGCVQLKAALARHLGPDF--APEHVAVGCGSVSLCQQLVQVTASVGDEVVFGWRSF 111 Query: 167 PAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTG 226 Y + G T ++ M +T RT +IF C+PNNPT Sbjct: 112 ELYPPQVRVAGAIPIQVPLTDHTFDLYAMLAT----------VTDRTRLIFVCNPNNPTS 161 Query: 227 YVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFA 286 V L + V+ + +I D AY +I DG + A + + +FSK Sbjct: 162 TVVGPDALARFVEAVPAH-ILIAIDEAYVEYIRDGMRPDSLGLVRAHNNVVVLRTFSKAY 220 Query: 287 GFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIR 346 G G+R+G++I + +I ++ S+I QA +A S E+ Sbjct: 221 GLAGLRIGYAIGHPD--------VITALDKVYVPFT--VSSIGQAAAIA--SLDAADELL 268 Query: 347 SVNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSWDVFNEILENTHIITVPG 406 + + R + L + G A ++W+ GS++ D + + I+ P Sbjct: 269 ARTDTVVAERARVSAELRAAGF-TLPPSQANFVWLPL-GSRTQDFVEQ-AADARIVVRP- 324 Query: 407 SGFGPGGEEYLRISGFGRRDHIVEASKRLQNFFNTRTK 444 +G G +R++ ++ +A R + + K Sbjct: 325 --YGTDG---VRVTVAAPEEN--DAFLRFARRWRSDQK 355 >1UU1-A nrPDB Length = 335 Score = 148 bits (373), Expect = 5e-36, Method: Composition-based stats. Identities = 69/383 (18%), Positives = 135/383 (35%), Gaps = 56/383 (14%) Query: 56 INRRELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNK 115 I +R + + + ++L + P PE + + L++ Y + Sbjct: 7 IAKRAYPYETEKRDKTYLALN--ENPFPFPEDLVDEVFR---RLNSDALRIYYDSPD--E 59 Query: 116 TLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDSSVI 175 L + I D + N V V +GA I + L+ PT+ Y + Sbjct: 60 ELIEKILSYLDTDF-LSKNNVSVGNGADEIIYVMMLMF---DRSVFFPPTYSCYRIFAKA 115 Query: 176 IGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLH 235 +G TK + P++ + DV+F +PNNPTG+V R+++ Sbjct: 116 VGAKFLEVPLTKDLR-------------IPEVNV-GEGDVVFIPNPNNPTGHVFEREEIE 161 Query: 236 QLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGW 295 +++ G+ + D AY F S + E + +FSK R+G+ Sbjct: 162 RIL----KTGAFVALDEAYYEF----HGESYVDFLKKYENLAVIRTFSKAFSLAAQRVGY 213 Query: 296 SIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKEN 355 + ++ + D + V FN S ++Q L + + E Sbjct: 214 VVASEKFI---------DAYNRVRLPFN-VSYVSQMFAKVALDHREI--FEERTKFIVEE 261 Query: 356 RKILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSWDVFNEILENTHIITVPGSGFGPGGEE 415 R+ + L +G ++ ++V F + + E L ++ F G Sbjct: 262 RERMKSALREMGYRITDSRGNF-VFV-FMEKEEKERLLEHLRTKNVAV---RSFREG--- 313 Query: 416 YLRISGFGRRD--HIVEASKRLQ 436 +RI+ R + I+ + + Sbjct: 314 -VRITIGKREENDMILRELEVFK 335 >4GDY-A nrPDB Length = 439 Score = 147 bits (372), Expect = 6e-36, Method: Composition-based stats. Identities = 67/414 (16%), Positives = 136/414 (32%), Gaps = 41/414 (9%) Query: 59 RELEHIEKHPNVQLISLGTGDTT-----EPIPEQITSHMSNFAHGLSTVEGYRGYGLEQG 113 R + I +ISL G + G ++ Y G Sbjct: 20 RTMTDILSRGPKSMISLAGGLPNPNMFPFKTAVITVENGKTIQFGEEMMKRALQYSPSAG 79 Query: 114 NKTLRKAIAETFYR---------DLHVKSN----EVFVSDGAQSDI-SRLQLLLGSNVTI 159 L + +H + ++ V+ G+Q + ++++ + Sbjct: 80 IPEL----LSWLKQLQIKLHNPPTIHYPPSQGQMDLCVTSGSQQGLCKVFEMIINPGDNV 135 Query: 160 AVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTP--RTDVIF 217 + +P + + S +G + + + V + + P+ A P T Sbjct: 136 LLDEPAYSGTLQSLHPLGCN-IINVASDESGIVPDSLRDILSRWKPEDAKNPQKNTPKFL 194 Query: 218 FCSPN--NPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREV 275 + PN NPTG + ++ ++ + A+ +II D Y + + Sbjct: 195 YTVPNGNNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNSGRVPTFLSMDVDGR 254 Query: 276 AIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLA 335 I SFSK +G+R+G+ P L+ I + ++FN I+Q Sbjct: 255 VIRADSFSKIIS-SGLRIGFLTGPKPLIERVILHI--QVSTLHPSTFNQLM-ISQ-LLHE 309 Query: 336 CLSSGGLKEIRSVNNYYKENRKILMDTLVS--LGL-KVYGGVNAPYLWVHFKGSKS-WDV 391 G + + V ++Y + ++ GL + + +LW+ KG ++ Sbjct: 310 WGEEGFMAHVDRVIDFYSNQKDAILAAADKWLTGLAEWHVPAAGMFLWIKVKGINDVKEL 369 Query: 392 FNEILENTHIITVPGSGF---GPGGEEYLRISG-FGRRDHIVEASKRLQNFFNT 441 E ++ +PG+ F YLR S + + A + L Sbjct: 370 IEEKAVKMGVLMLPGNAFYVDSSAPSPYLRASFSSASPEQMDVAFQVLAQLIKE 423 >1IJI-A nrPDB Length = 356 Score = 146 bits (369), Expect = 1e-35, Method: Composition-based stats. Identities = 66/320 (20%), Positives = 115/320 (35%), Gaps = 33/320 (10%) Query: 119 KAIAETFYRDLHVKSNEVFVSDGAQSDISRL-QLLLGSN-VTIAVQDPTFPAYIDSSVII 176 KA+ E + + VK +V VS GA I L + I PT+ Y S+ I Sbjct: 61 KAVIENYAQYAGVKPEQVLVSRGADEGIELLIRAFCEPGKDAILYCPPTYGMYSVSAETI 120 Query: 177 GQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQ 236 G +Q V++ CSPNNPTG + + + Sbjct: 121 GVECRTVPTLDNWQL----------DLQGISDKLDGVKVVYVCSPNNPTGQLINPQDFRT 170 Query: 237 LVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWS 296 L++ + +I++ D AY F S+ + + SK G+R G++ Sbjct: 171 LLELTRGK-AIVVADEAYIEFCPQA---SLAGWLAEYPHLAILRTLSKAFALAGLRCGFT 226 Query: 297 IIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENR 356 + +E +IN +++ S LS G+ +R R Sbjct: 227 LANEE--------VINLLMKVIAP--YPLSTPVADIAAQALSPQGIVAMRERVAQIIAER 276 Query: 357 KILMDTLVSLG-LKVYGGVNAPYLWVHFKGSKSWDVFNEILENTHIITVPGSGFGPGGEE 415 + L+ L + ++ Y+ FK S + VF + + II + P Sbjct: 277 EYLIAALKEIPCVEQVFDSETNYILARFKASSA--VFKSLWDQ-GIILRDQNK-QPSLSG 332 Query: 416 YLRISGFGRRD--HIVEASK 433 LRI+ R + +++A + Sbjct: 333 CLRITVGTREESQRVIDALR 352 >3FFH-A nrPDB Length = 363 Score = 146 bits (367), Expect = 3e-35, Method: Composition-based stats. Identities = 61/315 (19%), Positives = 114/315 (36%), Gaps = 36/315 (11%) Query: 116 TLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRLQ-LLLGSNVTIAVQDPTFPAYIDSSV 174 +LRK +A+ + ++ E+ + G I L +LL + + PTF Y +++ Sbjct: 71 SLRKEVADFYQ----LEEEELIFTAGVDELIELLTRVLLDTTTNTVMATPTFVQYRQNAL 126 Query: 175 IIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQL 234 I G + + G ++ A+ +T +++ C+PNNPTG + Sbjct: 127 IEGAEVR---------EIPLLQDGEHDLEGMLNAIDEKTTIVWICNPNNPTGNYIELADI 177 Query: 235 HQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLG 294 +D + +++ D AY ++ P ++ + I +FSK G R+G Sbjct: 178 QAFLDRVPS-DVLVVLDEAYIEYVT-PQPEKHEKLVRTYKNLIITRTFSKIYGLASARVG 235 Query: 295 WSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGL--KEIRSVNNYY 352 + I E++ IV FN S I Q + + + S N Sbjct: 236 YGIADKEIIRQ---------LNIVRPPFNTTS-IGQKLAIEAIKDQAFIGECRTSNANGI 285 Query: 353 KENRKILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSWDVFNEILENTHIITVPGSGFGPG 412 K+ + + L N ++ + LE IT G+ G Sbjct: 286 KQ-YEAFAKRFEKVKL---YPANGNFVLIDLGIEAGTIFSY--LEKNGYITRSGAALGFP 339 Query: 413 GEEYLRISGFGRRDH 427 +RI+ D+ Sbjct: 340 TA--VRITIGKEEDN 352 >3CQ5-A nrPDB Length = 369 Score = 141 bits (354), Expect = 8e-34, Method: Composition-based stats. Identities = 71/402 (17%), Positives = 140/402 (34%), Gaps = 44/402 (10%) Query: 42 VNLEKLKNNYLFPEINRRELEHIEKHPNVQL-ISLGTGDTTEPIPEQITSHMSNFAHGLS 100 ++ K+ + L P EH P + + I L T + P E + + + A Sbjct: 2 SHMTKITLSDL-PLREELRGEHAYGAPQLNVDIRLNTNENPYPPSEALVADL--VATVDK 58 Query: 101 TVEGYRGYGLEQGNKTLRKAIAETFYRDLHVK--SNEVFVSDGAQSDISRL-QLLLGSNV 157 Y E+ LR +A + V + ++ ++G+ + +L Q G Sbjct: 59 IATELNRY-PERDAVELRDELAAYITKQTGVAVTRDNLWAANGSNEILQQLLQAFGGPGR 117 Query: 158 TIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIF 217 T P++ + + + ++ + + + PD ++F Sbjct: 118 TALGFQPSYSMHPILAKGTHTEFIAVSRGADFRIDMDVALEEIRAKQPD--------IVF 169 Query: 218 FCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAI 277 +PNNPTG V S + ++++ A I+I D AYA F S ++ E + + Sbjct: 170 VTTPNNPTGDVTSLDDVERIINVAP---GIVIVDEAYAEFSPSPSATTLLEKYPTK--LV 224 Query: 278 EVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACL 337 + SK F G RLG+ + P D +V ++ S ++QA + L Sbjct: 225 VSRTMSKAFDFAGGRLGYFVAN---------PAFIDAVMLVRLPYH-LSALSQAAAIVAL 274 Query: 338 SSGGLKEIRSVNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSWDVFNEILE 397 R + L LG V + + F + + L+ Sbjct: 275 RHSADT--LGTVEKLSVERVRVAARLEELGYAVVPSESNFVFFGDFSDQHA--AWQAFLD 330 Query: 398 NTHIITVPGSGFGPGGEEYLRISGFGRRDH---IVEASKRLQ 436 +I G +LR + ++ + A++ ++ Sbjct: 331 RGVLIRDVGIA------GHLRTTIGVPEENDAFLDAAAEIIK 366 >3TCM-A nrPDB Length = 500 Score = 141 bits (354), Expect = 9e-34, Method: Composition-based stats. Identities = 81/398 (20%), Positives = 134/398 (33%), Gaps = 48/398 (12%) Query: 89 TSHMSNFAHGLSTVEG--YRGYGLEQGNKTLRKAIAETFYRDLHVKS--NEVFVSDGAQS 144 +S L+ + G Y QG LR AIA + +++F++DGA Sbjct: 109 ADSISRAKQILAMIPGRATGAYSHSQGIHGLRDAIASGIASRDGFPANADDIFLTDGASP 168 Query: 145 DISRLQLLL--GSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNS 202 + + LL I V P +P Y S + G + Sbjct: 169 GVHLMMQLLIRNEKDGILVPIPQYPLYSASIALHGGA-LVPYYLNESTGWGLETSDVKKQ 227 Query: 203 FFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAA--FIED 260 + + +P NPTG V + + + +V F K G +++ D Y ++++ Sbjct: 228 LEDARSRGINVRALVVINPGNPTGQVLAEENQYDIVKFCKNEGLVLLADEVYQENIYVDN 287 Query: 261 GSPRSIYEI-----PGAREVAIEVS-SFSK-FAGFTGVRLGWSIIPDELLYSNGFPIIND 313 S +I G ++ + S SK + G G R G+ + P+ Sbjct: 288 KKFHSFKKIVRSLGYGEEDLPLVSYQSVSKGYYGECGKRGGYF-----EITGFSAPVREQ 342 Query: 314 FHRIVTTSFNGASNIA-QAGGLACLSS---------GGLKEIRSVNNYYKENRKILMDTL 363 ++I S N SNI Q ++ E + K L Sbjct: 343 IYKIA--SVNLCSNITGQILASLVMNPPKASDESYASYKAEKDGILASLARRAKALEHAF 400 Query: 364 VSL-GLKVYGGVNAPYLWVHF-----------KGSKSWDVFN--EILENTHIITVPGSGF 409 L G+ A Y++ +K+ D F +LE+T I+ VPGSGF Sbjct: 401 NKLEGITCNEAEGAMYVFPQICLPQKAIEAAKAANKAPDAFYALRLLESTGIVVVPGSGF 460 Query: 410 GP-GGEEYLRISGFGRRDHIVEASKRLQNFFNTRTKHF 446 G G + R + + D I R F + Sbjct: 461 GQVPGTWHFRCTILPQEDKIPAVISRFTVFHEAFMSEY 498 >3FKD-A nrPDB Length = 350 Score = 137 bits (344), Expect = 1e-32, Method: Composition-based stats. Identities = 64/356 (17%), Positives = 127/356 (35%), Gaps = 45/356 (12%) Query: 89 TSHMSNFAHGLSTVEGYRGYG-LEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDIS 147 H+ H + + R Y + G LR+ +A + V +N + V++G + Sbjct: 30 KDHLEK--HLVENLNCIRHYPEPDAGT--LRQMLA----KRNSVDNNAILVTNGPTAAFY 81 Query: 148 RL-QLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPD 206 ++ Q GS IA+ P+F Y D+ + F+ P+N + Sbjct: 82 QIAQAFRGSRSLIAI--PSFAEYEDACRMYEHEVCFY---------------PSNEDIGE 124 Query: 207 LAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSI 266 + D + C+PNNP G + R ++ +L++ + + D +Y +F + R Sbjct: 125 ADFS-NMDFCWLCNPNNPDGRLLQRTEILRLLN--DHPDTTFVLDQSYVSFTTEEVIRPA 181 Query: 267 YEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGAS 326 R+ + V SFS G G+R+G+ + + R+ S A Sbjct: 182 D--IKGRKNLVMVYSFSHAYGIPGLRIGYIVANKDF-----------MKRVAAFSTPWAV 228 Query: 327 NIAQAGGLACLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFKGS 386 N + + + + + + L L + + K Sbjct: 229 NALAIEAAKFILIHPAQFTLPIRKWQRNTVDFI-TALNRLDGVEVHPSGTTFFLLRLKKG 287 Query: 387 KSWDVFNEILENTHIITVPGSGFGPGGEEYLRISGFGRRDHIVEASKRLQNFFNTR 442 + ++ +LE +++ S F E Y+RI+ + + K L+ F Sbjct: 288 TAAELKKYMLEEYNMLIRDASNFRGLDESYVRITTQRPAQNQL-FIKALETFLEKY 342 >3NRA-A nrPDB Length = 407 Score = 137 bits (344), Expect = 1e-32, Method: Composition-based stats. Identities = 65/416 (15%), Positives = 132/416 (31%), Gaps = 33/416 (7%) Query: 44 LEKL-KNNYLFPEINRRELEHIEKHPNVQL----ISLGTGDTT--EPIPEQITSHMSNFA 96 +KL +N E+ + + + GD EP P + Sbjct: 8 FKKLGTDNAPGQEVRQSAAGLEALIRGAPIEGRPVDFSHGDVDAHEPTP-----GAFDLF 62 Query: 97 HGLSTVEGYRGYGLEQGNKTLRKAIAETFYRDLH---VKSNEVFVSDGAQSDIS-RLQLL 152 G + Y +G+ +R +A + + ++ G Q + + Sbjct: 63 SAGVQSGGVQAYTEYRGDLGIRDLLAPRLAAFTGAPVDARDGLIITPGTQGALFLAVAAT 122 Query: 153 LGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPR 212 + +A+ P + + + ++ G Y + G + + + A Sbjct: 123 VARGDKVAIVQPDY--FANRKLVEFFEGEMVPVQLDYVSADETRAGLDLTGLEE-AFKAG 179 Query: 213 TDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGA 272 V F +PNNP G V S +++ Q+ A G+ +I D Y+ G+ + A Sbjct: 180 ARVFLFSNPNNPAGVVYSAEEIGQIAALAARYGATVIADQLYSRLRYAGASYTHLRAEAA 239 Query: 273 --REVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQ 330 E + + SK +G RLG + II ++ A+ +Q Sbjct: 240 VDAENVVTIMGPSKTESLSGYRLGVAFGSRA--------IIARMEKLQAIVSLRAAGYSQ 291 Query: 331 AGGLACLSSGGLKEIRSVNNYYKENRKILMDTLVS-LGLKVYGGVNAPYLWVHFK--GSK 387 A + ++ R L+ L G+ YL+ Sbjct: 292 AVLRGWFDEAPG-WMEDRIARHQAIRDELLHVLRGCEGVFARTPQAGSYLFPRLPKLAVA 350 Query: 388 SWDVFNEILENTHIITVPGSGFGPGGEEYLRISGFGRRDHIVEASKRLQNFFNTRT 443 + + ++ PG+ F P + +R++ + V A++R+ Sbjct: 351 PAEFVKILRLQAGVVVTPGTEFSPHTADSVRLNFSQDHEAAVAAARRIVTLVERYR 406 >3IHJ-A nrPDB Length = 498 Score = 136 bits (342), Expect = 2e-32, Method: Composition-based stats. Identities = 83/445 (18%), Positives = 143/445 (32%), Gaps = 74/445 (16%) Query: 60 ELEHIEKHPNVQLISLGTGDTT----------------------EPIPEQITSHMSNFAH 97 EL+ K P ++I GD P Sbjct: 53 ELQRGIKKPFTEVIRANIGDAQAMGQQPITFLRQVMALCTYPNLLDSPSFPEDAKKRARR 112 Query: 98 GLSTVEGYR--GYGLEQGNKTLRKAIAETFYR---DLHVKSNEVFVSDGAQSDISRLQLL 152 L G Y QG +R+ +A R + + ++++ GA IS + + Sbjct: 113 ILQACGGNSLGSYSASQGVNCIREDVAAYITRRDGGVPADPDNIYLTTGASDGISTILKI 172 Query: 153 LGSN-----VTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDL 207 L S + + P +P Y S+VI +N + + Sbjct: 173 LVSGGGKSRTGVMIPIPQYPLY--SAVISELDAIQVNYYLDEENCWALNVNELRRAVQEA 230 Query: 208 AMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRS-- 265 V+ +P NPTG V SRK + ++ FA ++ D Y + R Sbjct: 231 KDHCDPKVLCIINPGNPTGQVQSRKCIEDVIHFAWEEKLFLLADEVYQDNVYSPDCRFHS 290 Query: 266 ----IYEIPGAREVAIEVSSF---SKFA-GFTGVRLGWSIIPDELLYSNGFPIINDFHRI 317 +YE+ +E++SF SK G G R G+ E++ N P I Sbjct: 291 FKKVLYEMGPEYSSNVELASFHSTSKGYMGECGYRGGYM----EVI--NLHPEIKGQLVK 344 Query: 318 VTTSFNGASNIAQAGGLACLS---------SGGLKEIRSVNNYYKENRKILMDTLVS-LG 367 + + QA ++ +E SV + K+ D G Sbjct: 345 LLSVRLCPPVSGQAAMDIVVNPPVAGEESFEQFSREKESVLGNLAKKAKLTEDLFNQVPG 404 Query: 368 LKVYGGVNAPYLWVHF-------------KGSKSWDVFNEILENTHIITVPGSGFG-PGG 413 + A Y + + + ++LE T I VPGSGFG G Sbjct: 405 IHCNPLQGAMYAFPRIFIPAKAVEAAQAHQMAPDMFYCMKLLEETGICVVPGSGFGQREG 464 Query: 414 EEYLRISGFGRRDHIVEASKRLQNF 438 + R++ + + +++++F Sbjct: 465 TYHFRMTILPPVEKLKTVLQKVKDF 489 >1LC8-A nrPDB Length = 364 Score = 135 bits (339), Expect = 4e-32, Method: Composition-based stats. Identities = 67/379 (17%), Positives = 125/379 (32%), Gaps = 41/379 (10%) Query: 59 RELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLR 118 RE + QL+ +P + + + + + L Sbjct: 13 REPATVLGISPDQLLDFSANINPLGMPVSVKRALIDNLDCIERYPDADYF-------HLH 65 Query: 119 KAIAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQ 178 +A+A R V ++ + +G I + L + V P F Y + G Sbjct: 66 QALA----RHHQVPASWILAGNGETESIFTVASGLKPRRAMIV-TPGFAEYGRALAQSGC 120 Query: 179 TGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLV 238 + G + A+TP D +F C+PNNPTG + R L + Sbjct: 121 EIRRWS--------LREADGWQLTDAILEALTPDLDCLFLCTPNNPTGLLPERPLLQAIA 172 Query: 239 DFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREV--AIEVSSFSKFAGFTGVRLGWS 296 D K+ +I D A+ FI P IP ++ + S +KF G+RLG+ Sbjct: 173 DRCKSLNINLILDEAFIDFI----PHETGFIPALKDNPHIWVLRSLTKFYAIPGLRLGYL 228 Query: 297 IIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENR 356 + D+ + + +A G L + ++ ++ +E Sbjct: 229 VNSDDAAMA---------RMRRQQMPWSVNALAALAGEVALQDSAWQ--QATWHWLREEG 277 Query: 357 KILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSWDVFNEILENTHIITVPGSGFGPGGEEY 416 L L L A YL + + D+ +L I+ + + Y Sbjct: 278 ARFYQALCQLPLLTVYPGRANYLLLRC-EREDIDLQRRLLTQ-RILIRSCANYPGLDSRY 335 Query: 417 LRISG--FGRRDHIVEASK 433 R++ + + ++ A + Sbjct: 336 YRVAIRSAAQNERLLAALR 354 >4RAE-A nrPDB Length = 394 Score = 135 bits (339), Expect = 5e-32, Method: Composition-based stats. Identities = 71/368 (19%), Positives = 129/368 (35%), Gaps = 43/368 (11%) Query: 73 ISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETF--YRDLH 130 + L T + P + + + Y ++ LR +A + Sbjct: 35 VRLNTNENPHPPTRALVDDVVRSVREAAI--DLHRY-PDRDAVALRADLAGYLTAQTGIQ 91 Query: 131 VKSNEVFVSDGAQSDISRL-QLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKY 189 + ++ ++G+ + +L Q G + P++ + S + + Sbjct: 92 LGVENIWAANGSNEILQQLLQAFGGPGRSAIGFVPSYSMHPIISDGTHTEWIEASRANDF 151 Query: 190 QNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIII 249 V + + + DV+F SPNNP+G S L +L+D A I I Sbjct: 152 GLDVDVAVA--------AVVDRKPDVVFIASPNNPSGQSVSLPDLCKLLDVAP---GIAI 200 Query: 250 FDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFP 309 D AY F S S+ E ++ + + SK F G RLG+ I P Sbjct: 201 VDEAYGEFSSQPSAVSLVEEYPSK--LVVTRTMSKAFAFAGGRLGYLIA---------TP 249 Query: 310 IINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLK 369 + D +V ++ S++ QA A L + SV E R+ + +L +G + Sbjct: 250 AVIDAMLLVRLPYH-LSSVTQAAARAALRHSD-DTLSSVAALIAE-RERVTTSLNDMGFR 306 Query: 370 VYGGVNAPYLWVHFKGSKSWDVFNEILENTHIIT----VPG-----SGFGPGGEEYLRIS 420 V L+ F + + + L I+ +PG +G + +LR S Sbjct: 307 VIPSDANFVLFGEFADAPA--AWRRYL-EAGILIRDVGIPGYLRATTGLAEENDAFLRAS 363 Query: 421 GFGRRDHI 428 D + Sbjct: 364 ARIATDLV 371 >5DJ3-A nrPDB Length = 376 Score = 134 bits (337), Expect = 7e-32, Method: Composition-based stats. Identities = 57/330 (17%), Positives = 116/330 (35%), Gaps = 40/330 (12%) Query: 126 YRDLHVKSNEVFVSDGAQSDISRLQLLLGSN-VTIAVQDPTFPAYIDSSVIIGQTGHFHE 184 + V + + L L ++ +A+ PTF D G Sbjct: 74 QHGYPAEPGRVLSCYSSSVSMEILARSLSASVDRVALVHPTFDNIADLLRGNG------- 126 Query: 185 KTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTN 244 ++V + + + +F +PNNPTG V + ++L +L + + Sbjct: 127 -----LDLVPVEEDALHGADLSAELLSSVGCVFVTTPNNPTGRVLAEERLRRLAEQCAEH 181 Query: 245 GSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSI------I 298 G+++ D+++ F + A + + K ++ G + + Sbjct: 182 GTVLALDTSFRGFDAAAHYDHYAVLQEAGCRWVVIEDTGKLWPTLDLKAGLLVFSEDIGL 241 Query: 299 PDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKI 358 P E +YS+ I+ ++ S A GGLA L + NR + Sbjct: 242 PVEKIYSD---ILLGVSPLILALIREFSRDAADGGLADLH-----------AFILHNRSV 287 Query: 359 LMDTLVSL-GLKVYGGVNAPYL-WVHFKGSKSWDVFNEILENTHIITVPGSGFG----PG 412 + L + G+ + + V F G +V+ E L+ H+ +P F Sbjct: 288 VRRALAGVEGVSFPDPESRSSVERVAFAGRTGTEVWEE-LQRHHVFALPCRQFHWAEPSD 346 Query: 413 GEEYLRISGFGRRDHIVEASKRLQNFFNTR 442 G+ +RI+ + + ++ + L+ TR Sbjct: 347 GDHMVRIALSRSTEPLEKSVQVLRTVLETR 376 >3HDO-A nrPDB Length = 360 Score = 132 bits (333), Expect = 3e-31, Method: Composition-based stats. Identities = 59/361 (16%), Positives = 122/361 (33%), Gaps = 46/361 (12%) Query: 79 DTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFV 138 + P PE + + + + + Y ++ LR+ E + + + + Sbjct: 36 NPYPPSPEVVKAILEELGPDGAALRIY----PSASSQKLREVAGELY----GFDPSWIIM 87 Query: 139 SDGAQSDIS-RLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPC 197 ++G+ ++ ++ I P++ Y + + G T ++ Sbjct: 88 ANGSDEVLNNLIRAFAAEGEEIGYVHPSYSYYGTLAEVQGARVRTFGLTGDFRIAG---- 143 Query: 198 GPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAF 257 FP+ V F +PN P G + + +L +++ D YA F Sbjct: 144 ------FPERY---EGKVFFLTTPNAPLGPSFPLEYIDELARRCA---GMLVLDETYAEF 191 Query: 258 IEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRI 317 E + E+ E + + SK G+R+G +I E++ + I D + + Sbjct: 192 AES----NALELVRRHENVVVTRTLSKSYSLAGMRIGLAIARPEVIAALDK--IRDHYNL 245 Query: 318 VTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLKVYGGVNAP 377 +AQA +A L + +E R+ L S+G V Sbjct: 246 DR--------LAQAACVAALRD--QAYLSECCRRIRETREWFTTELRSIGYDVIPSQGN- 294 Query: 378 YLWVHFKGSKSWDVFNEILENTHIITVPGSGFGPGGEEYLRISGFGRRDHIVEASKRLQN 437 YL+ V++ + ++ S P +RIS R+ + + L+ Sbjct: 295 YLFATPPDRDGKRVYDGLYAR-KVLVRHFS--DPLLAHGMRISIGT-REEMEQTLAALKE 350 Query: 438 F 438 Sbjct: 351 I 351 >3GET-A nrPDB Length = 365 Score = 132 bits (332), Expect = 3e-31, Method: Composition-based stats. Identities = 73/410 (17%), Positives = 136/410 (33%), Gaps = 58/410 (14%) Query: 41 NVNLEKLKNNYLFPEINRRELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLS 100 N L L N +I E+ K ++I L + + P + + A Sbjct: 5 NEFLNNLSNYEPGKDIEVIAKEYGVK----EVIKLASNENPFGTPPKAIECLRQNA---- 56 Query: 101 TVEGYRGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDI-SRLQLLLGSNVTI 159 Y + L+ +A+ + V++ + + G+ I + L S Sbjct: 57 --NKAHLYPDDSMI-ELKSTLAQKYK----VQNENIIIGAGSDQVIEFAIHSKLNSKNAF 109 Query: 160 AVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRT--DVIF 217 TF Y + G + + N F L T + +IF Sbjct: 110 LQAGVTFAMYEIYAKQCGAKCYKTQSITH-----------NLDEFKKLYETHKDEIKLIF 158 Query: 218 FCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFI---EDGSPRSIYEIPGARE 274 C PNNP G + + + +++ D+AY F + E+ + Sbjct: 159 LCLPNNPLGECLDASEATEFIKGVNE-DCLVVIDAAYNEFASFKDSKKHLEPCELIKEFD 217 Query: 275 VAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGL 334 + + +FSK G G+R+G+ I II+ F+++ FN SN+A + Sbjct: 218 NVLYLGTFSKLYGLGGLRIGYGIANA--------NIISAFYKL-RAPFN-VSNLALKAAV 267 Query: 335 ACLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSWDVFNE 394 A + E NN+ ++ + +K+ + F S D+ + Sbjct: 268 AAMDDDEFTEKTLENNF--SQMELYKEFAKKHNIKIIDSYTNFITYF-FDEKNSTDLSEK 324 Query: 395 ILENTHIITVPGSGFGPGGEEYLRISGFGRRDHIVEASKRLQNFFNTRTK 444 +L II +G +RI+ ++ + FF K Sbjct: 325 LL-KKGIIIRNLKSYGLNA---IRITIGTSYEN--------EKFFTEFDK 362 >3LY1-A nrPDB Length = 354 Score = 130 bits (327), Expect = 1e-30, Method: Composition-based stats. Identities = 54/328 (16%), Positives = 111/328 (33%), Gaps = 33/328 (10%) Query: 120 AIAETFYRDLHVKSNEVFVSDGAQSDI-SRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQ 178 + V++ + ++ G+ I + ++ + + + T+ + I G Sbjct: 55 MLGNKLAAHHQVEAPSILLTAGSSEGIRAAIEAYASLEAQLVIPELTYGDGEHFAKIAGM 114 Query: 179 TGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLV 238 + + + +A +++ +PNNPTG + + + Sbjct: 115 KVTKVKMLDNWAFDI-------EGLKAAVAAYSGPSIVYLVNPNNPTGTITPADVIEPWI 167 Query: 239 DFAKTNGSIIIFDSAYAAFIEDGSPRSIYE-IPGAREVAIEVSSFSKFAGFTGVRLGWSI 297 +K ++ I D AYA F+ D RSI I E I + +FSK G+R+G+++ Sbjct: 168 -ASKPANTMFIVDEAYAEFVNDPRFRSISPMITQGAENIILLKTFSKIHAMAGMRVGYAV 226 Query: 298 IPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRK 357 +I R V S + LA ++ +N +R+ Sbjct: 227 A--------HPTVIALMGRYVAGEKINFSGV--DAALASMNDSAFITYSKKSN--DVSRQ 274 Query: 358 ILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSWDVFNEILENTHIITVPGSGFGPGGEEYL 417 IL+ L L L K + + + ++ G F P + + Sbjct: 275 ILLKALEDLKLPYLPSEGNFVFHQLVVPLKD---YQTHMADAGVLI--GRAF-PPADNWC 328 Query: 418 RISGFGRRDHIVEASKRLQNFFNTRTKH 445 RIS ++ + + + K Sbjct: 329 RISLGTPQE-----MQWVADTMREFRKK 351 >3FTB-A nrPDB Length = 361 Score = 130 bits (326), Expect = 2e-30, Method: Composition-based stats. Identities = 53/314 (16%), Positives = 118/314 (37%), Gaps = 33/314 (10%) Query: 110 LEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQDPTFPAY 169 + + L K+I +K + + +GA I L I + P++ Y Sbjct: 59 PDVNYRRLNKSIENYLK----LKDIGIVLGNGASEIIELSISLF---EKILIIVPSYAEY 111 Query: 170 IDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVA 229 ++ G + F Y+ + ++ D + +PNNP G + Sbjct: 112 EINAKKHGVSVVFS----------YLDENMCIDYEDIISKIDDVDSVIIGNPNNPNGGLI 161 Query: 230 SRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFT 289 ++++ ++ A+ II D A+ F D S + EI + I + + +KF Sbjct: 162 NKEKFIHVLKLAEEKKKTIIIDEAFIEFTGDPSSSFVGEIKNYSCLFI-IRAMTKFFAMP 220 Query: 290 GVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVN 349 G+R G+ I ++ + + N ++ + A+ + CL I Sbjct: 221 GIRFGYGITNNKEIAAKIKAKQNPWN---------INCFAEMAAINCLKD--TNYIEESL 269 Query: 350 NYYKENRKILMDTLVSLGL--KVYGGVNAPYLWVHFKGSKSWDVFNEILENTHIITVPGS 407 + K+ RK ++ L +G +V+ +A ++ + +++ +L+ I+ Sbjct: 270 LWIKKERKRFIEELNKIGFIKRVFSP-HANFVLCRLENISGEKLYDSLLKE-DIVIRRCC 327 Query: 408 GFGPGGEEYLRISG 421 F + ++R + Sbjct: 328 NFIGLDDSFVRFAI 341 >3IF2-A nrPDB Length = 444 Score = 125 bits (313), Expect = 4e-29, Method: Composition-based stats. Identities = 65/373 (17%), Positives = 123/373 (32%), Gaps = 51/373 (13%) Query: 108 YGLEQGNKTLRKAIAETFYR--DLHVKSNEVFVSDGAQSDISRLQLLLG----------- 154 Y QG+ A+ F R D ++ S + +++G+Q+ L L G Sbjct: 79 YSNPQGDSAFIDALVGFFNRHYDWNLTSENIALTNGSQNAFFYLFNLFGGAFVNEHSQDK 138 Query: 155 -----SNVTIAVQDPTFPAYIDSSVII---GQTGHFHEKTKKYQNVVYMPCGPNNSFFPD 206 + P + Y D V ++ + + + Sbjct: 139 ESKSVDKSILLPLTPEYIGYSDVHVEGQHFAAVLPHIDEVTHDGEEGFFKYRVDFEALEN 198 Query: 207 LAMTPRTDVIFFCS--PNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPR 264 L + C P NPTG V + +++ L + AK +I D+AY + + Sbjct: 199 LPALKEGRIGAICCSRPTNPTGNVLTDEEMAHLAEIAKRYDIPLIIDNAYG--MPFPNII 256 Query: 265 SIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNG 324 I S SK G G+R G + +I + Sbjct: 257 YSDAHLNWDNNTILCFSLSKI-GLPGMRTGIIVADA--------KVIEAVSAMNAVVNLA 307 Query: 325 ASNIAQAGGLACLSSGGLKEI--RSVNNYYKENR----KILMDTLVSLGLKVYGGVNAPY 378 + A +++ +K++ + +Y++ K+L L L ++ A + Sbjct: 308 PTRFGAAIATPLVANDRIKQLSDNEIKPFYQKQATLAVKLLKQALGDYPLMIHKPEGAIF 367 Query: 379 LWVHFKGS--KSWDVFNEILENTHIITVPGSGFGPG--------GEEYLRISGFGRRDHI 428 LW+ FK + D++ E L+ + VP F PG E +R+S + Sbjct: 368 LWLWFKDLPISTLDLY-ERLKAKGTLIVPSEYFFPGVDVSDYQHAHECIRMSIAADEQTL 426 Query: 429 VEASKRLQNFFNT 441 ++ K + Sbjct: 427 IDGIKVIGEVVRE 439 >6HNB-A nrPDB Length = 491 Score = 125 bits (313), Expect = 5e-29, Method: Composition-based stats. Identities = 75/435 (17%), Positives = 128/435 (29%), Gaps = 79/435 (18%) Query: 76 GTGDTTEPIPEQITSHMSNFAHGLSTVEGYRG---YGLEQGNKTLRKAIAET--FYRDLH 130 G G E + A + YG G + I E + Sbjct: 70 GIGAPIEGENKTTIEVFKKAADNVPDQIELARSLQYGSTFGLPEFLQFIKEHTDMVHKVP 129 Query: 131 VKSNEVFVSDGAQSDISR-LQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKY 189 ++ +V VS G L+ TI V++ TF + ++S+ G ++ Sbjct: 130 YENWDVIVSVGNTEAWDSTLRTFCSKGDTILVEEYTFSSALESANGQG-VNTVPVTMDEF 188 Query: 190 QNVVYMPCGPNNSFFPDLAMTPRTDVIF-FCSPNNPTGYVASRKQLHQLVDFAKTNGSII 248 + + + + + ++ C+ NPTG S ++ Q+ D A +I Sbjct: 189 GIIPEKLEELMSRWVGN-----KPKFLYTICTGQNPTGSSLSAERRKQIYDIACKYDFLI 243 Query: 249 IFDSAY-----AAFIEDGSPRSIYEIPGARE----------------VAIEVSSFSKFAG 287 I D Y + +D + R + E + + SFSK Sbjct: 244 IEDEPYYFLQMETYTKDKAAREGKAVHDHDEFLKALVPSFISLDVEGRVVRLDSFSKVLA 303 Query: 288 FTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLA-CLSSGGLKEIR 346 G+RLGW + +LL H + + +G S L SG L + Sbjct: 304 -PGLRLGWIVGQKDLL-----ERYVRLHEVSVQNPSGFSEALANALLRKWGHSGYLDWLI 357 Query: 347 SVNNYYKENRKILMDTL----VSLGLKVYGGVNAPYLWVHFKGSKSWDVFNEILE----- 397 + Y R + +D L V + V SK + E LE Sbjct: 358 GLRAEYTHKRDVAIDALDQFVPKEVSSFNPPVAGMFFTVTLDASKHPK-YKEFLEDPLKV 416 Query: 398 ---------NTHIITVPGSGFGPGGEE-----------------YLRISGFGRRDHIVEA 431 + PGS F G+ + R + + + Sbjct: 417 EAAVHEQAIKQGCLLAPGSWFKAEGQSSPPQKNLPANPSHKTHIFFRGTYAA--VPLDQL 474 Query: 432 SKRLQNFFNTRTKHF 446 L+ F F Sbjct: 475 VVGLEKFGKAVRAEF 489 >3P1T-A nrPDB Length = 337 Score = 123 bits (308), Expect = 2e-28, Method: Composition-based stats. Identities = 65/325 (20%), Positives = 97/325 (29%), Gaps = 44/325 (13%) Query: 121 IAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTG 180 + + + + G R+ S + P F Y + G Sbjct: 56 VMRKLAEHFSCPEDNLMLVRGIDECFDRISAEFSS-MRFVTAWPGFDGYRARIAVSGLRH 114 Query: 181 HFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDF 240 T LA R D + +P+NPTG S +L QL Sbjct: 115 FEIGLTDDLLLDPND-----------LAQVSRDDCVVLANPSNPTGQALSAGELDQLRQR 163 Query: 241 AKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPD 300 A ++ D Y + S R+ G E + SFSK G G+RLG P Sbjct: 164 AGK----LLIDETYVDYS---SFRARGLAYGENE--LVFRSFSKSYGLAGLRLGALFGPS 214 Query: 301 ELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILM 360 EL I R G + A L + +E + + R+ + Sbjct: 215 EL--------IAAMKRKQWFCNVG--TLDLHALEAALDNDRAREAH-IAKTLAQRRR-VA 262 Query: 361 DTLVSLGLKVYGGVNAPYLWVHFKGSKSWDVFNEILENTHIITVPGSGFGPGGEEYLRIS 420 D L LG +V L + G ++ L I FG ++RIS Sbjct: 263 DALRGLGYRVASSEANFVLVENAAGERTL----RFLRERGIQVKDAGQFGL--HHHIRIS 316 Query: 421 GFGRRDHIVEASKRLQNFFNTRTKH 445 D+ RL + H Sbjct: 317 IGREEDN-----DRLLAALAEYSDH 336 >3G7Q-A nrPDB Length = 417 Score = 121 bits (302), Expect = 9e-28, Method: Composition-based stats. Identities = 76/402 (18%), Positives = 138/402 (34%), Gaps = 36/402 (8%) Query: 66 KHPNVQLISLGTGDTTEPIP--EQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAE 123 + P I LG G+ + + +++ + Y QG L A+A Sbjct: 29 RTPGA--IMLGGGNPAHIPAMQDYFQTLLTDMVESGKAADALCNYDGPQGKTALLNALAV 86 Query: 124 TFYR--DLHVKSNEVFVSDGAQSDISRLQLLL------GSNVTIAVQ-DPTFPAYIDSSV 174 ++ + +++G+QS L L GS + P + Y DS Sbjct: 87 LLRETLGWDIEPQNIALTNGSQSAFFYLFNLFAGRRADGSTKKVLFPLAPEYIGYADS-- 144 Query: 175 IIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQL 234 G + ++ + F L + T +I P NPTG V + ++L Sbjct: 145 --GLEDDLFVSARPNIELLPEGQFKYHVDFEHLHIGEETGMICVSRPTNPTGNVITDEEL 202 Query: 235 HQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLG 294 +L A + ++ D+AY + P I S SK G G R G Sbjct: 203 MKLDRLANQHNIPLVIDNAYG--VPFPGIIFSEARPLWNPNIILCMSLSK-LGLPGSRCG 259 Query: 295 WSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKE 354 I D+ + + I + + I++ + G + L E YY+ Sbjct: 260 IIIANDKTITA-----IANMNGIISLAPGGMGPAMMCEMIKRNDLLRLSETVIKPFYYQR 314 Query: 355 NRK---ILMDTLVSLGLKVYGGVNAPYLWVHFKGSK-SWDVFNEILENTHIITVPGSGFG 410 ++ I+ L ++ A +LW+ FK + ++ + L+ ++ VPG F Sbjct: 315 VQQTIAIIRRYLSEERCLIHKPEGAIFLWLWFKDLPITTELLYQRLKARGVLMVPGHYFF 374 Query: 411 PG-------GEEYLRISGFGRRDHIVEASKRLQNFFNTRTKH 445 PG + +R++ D I K L + Sbjct: 375 PGLDKPWPHTHQCMRMNYVPEPDKIEAGVKILAEEIERAWRE 416 >6HNV-A nrPDB Length = 524 Score = 117 bits (293), Expect = 1e-26, Method: Composition-based stats. Identities = 82/469 (17%), Positives = 150/469 (31%), Gaps = 88/469 (18%) Query: 49 NNYLFPEINRRELEHIEKHPNVQLISLG---TGDTTEPIPEQI-----TSHMSNFAHGLS 100 +Y F +I SL G T+ P I T H+S Sbjct: 61 VDYPFQKITTPSTTSSTAEEEPPSSSLNGSENGHQTKTPPSSIHTPQSTVHISRHTTDPK 120 Query: 101 TVEGYRG--YGLEQGNKTLRKAIAETFYR--DLHVKSNEVFVSDGAQSDIS-RLQLLLGS 155 ++ RG Y +G+ L + + R + VF++ GA ++ + L Sbjct: 121 LIDLARGLQYAAVEGHAPLLQFARDFIIRTHKPNYDDWNVFITTGASDGLNKAADVFLDD 180 Query: 156 NVTIAVQDPTFPAYIDSSVIIGQTG-----HFHEKTKKYQNVVYMPCGPNNSF-FPDLAM 209 I V++ TF ++ S G +F + ++ N +P+L Sbjct: 181 GDVILVEEFTFSPFLRFSDNAGAKAVPVKINFDNDSDGIDLTQFVDLLENWEKHYPNL-- 238 Query: 210 TPRTDVIF-FCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYA------------- 255 P+ ++ + NPTG+ S + ++ D A II D Y Sbjct: 239 -PKPKALYTIATGQNPTGFTQSLEFRKKIYDLAVKYDFAIIEDDPYGYLTLPKYEKPNIG 297 Query: 256 ----------------AFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIP 299 ++++ S E+ + V +FSK G+RLG+ + Sbjct: 298 GSGSGNNELKNDLEIDDYLKNHLTPSYLEL-DTTGRVLRVETFSKLFA-PGLRLGFIVGH 355 Query: 300 DELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLS------SGGLKEIRSVNNYYK 353 E +I+ GAS + Q + G L+ I + Y Sbjct: 356 KE--------VIDAVKNYSDVVNRGASGLTQTIVNNVIQENFKGVDGWLEWILKMRLNYS 407 Query: 354 ENRKILMDTLVSLG------LKVYGGVNAPYLWVHFKGSKSWDVFNEI------LENTHI 401 + +L+ ++ + V ++ K DV ++ L + I Sbjct: 408 YRKDLLLYSIFESQAYKKGYVDVIDPKAGMFVTFKINLPKDVDVLQKMKLLLWKLISYGI 467 Query: 402 ITVPG------SGFGPGGEEYLRISG--FGRRDHIVEASKRLQNFFNTR 442 + VPG F + R+ + I+E+ KRL + Sbjct: 468 LVVPGYNMTVDLEFSKDRSNFFRLCYALANNDEEILESGKRLTDAVYEF 516 >4JE5-A nrPDB Length = 503 Score = 117 bits (292), Expect = 1e-26, Method: Composition-based stats. Identities = 70/452 (15%), Positives = 127/452 (28%), Gaps = 99/452 (21%) Query: 74 SLGTGDTTEPIPEQITSHM-----------SNFAHGLSTVEGYR------GYGLEQGNKT 116 +L P P+ I + + ++A + YG G Sbjct: 57 NLSVDSPKPPFPQGIGAPIDEQNCIKYTVNKDYADKSANPSNDIPLSRALQYGFSAGQPE 116 Query: 117 LRKAIAETFY--RDLHVKSNEVFVSDGAQSDI-SRLQLLLGSNVTIAVQDPTFPAYIDSS 173 L I + DL K +V + G + S L++ I V+ +F + + S+ Sbjct: 117 LLNFIRDHTKIIHDLKYKDWDVLATAGNTNAWESTLRVFCNRGDVILVEAHSFSSSLASA 176 Query: 174 VIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIF-FCSPNNPTGYVASRK 232 G F + ++ P P+ +++ + NPTG + Sbjct: 177 EAQG-VITFPVPIDADGIIPEKLAKVMENWTPG---APKPKLLYTIPTGQNPTGTSIADH 232 Query: 233 QLHQLVDFAKTNGSIIIFDSAYA---------AFIEDGSPRS---------------IYE 268 + + A+ +I+ D Y E +S + Sbjct: 233 RKEAIYKIAQKYDFLIVEDEPYYFLQMNPYIKDLKEREKAQSSPKQDHDEFLKSLANTFL 292 Query: 269 IPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNI 328 I + SFSK G RLGW I+ + + + + Sbjct: 293 SLDTEGRVIRMDSFSKVLA-PGTRLGWITGS--------SKILKPYLSLHEMTIQAPAGF 343 Query: 329 AQAGGLACLSS----GGLKEIRSVNNYYKENR----KILMDTLVSLG-LKVYGGVNAPYL 379 Q A LS G L + + + Y R L L + + + Sbjct: 344 TQVLVNATLSRWGQKGYLDWLLGLRHEYTLKRDCAIDALYKYLPQSDAFVINPPIAGMFF 403 Query: 380 WVHFKGSKSWDVFNEI--------------LENTHIITVPGSGFGPGGEE---------- 415 V+ S + + + ++ VPGS F GE Sbjct: 404 TVNIDASVHPEFKTKYNSDPYQLEQSLYHKVVERGVLVVPGSWFKSEGETEPPQPAESKE 463 Query: 416 -------YLRISGFG-RRDHIVEASKRLQNFF 439 + R + + + E KRL + Sbjct: 464 VSNPNIIFFRGTYAAVSPEKLTEGLKRLGDTL 495 >2ZY3-A nrPDB Length = 546 Score = 113 bits (282), Expect = 2e-25, Method: Composition-based stats. Identities = 68/405 (16%), Positives = 130/405 (32%), Gaps = 76/405 (18%) Query: 108 YGLEQGNKTLRKAIAETF------YRDLHVKSNEVFVSDGAQSDIS------RLQLLLGS 155 Y + + + I + + +S +F +G + ++ +L LL + Sbjct: 134 YPVPPRMLNISEKIVRQYIIREMGADAIPSESVNLFAVEGGTAAMAYIFESLKLNGLLKA 193 Query: 156 NVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDV 215 +A+ P F YI+ + + E+ + P++ D P + Sbjct: 194 GDKVAIGMPVFTPYIEIPELA---QYALEEVAINADPSLNWQYPDSE--LDKLKDPAIKI 248 Query: 216 IFFCSPNNPTGYVASRKQLHQLVDFAKTN--GSIIIFDSAYAAFIEDGSPRSIYEIPGAR 273 F +P+NP ++ L ++ + + +I+ D Y F +D +S++ I Sbjct: 249 FFCVNPSNPPSVKMDQRSLERVRNIVAEHRPDLMILTDDVYGTFADD--FQSLFAI--CP 304 Query: 274 EVAIEVSSFSKFAGFTGVRLGWSII-----------------------------PDELLY 304 E + V SFSK+ G TG RLG PD Sbjct: 305 ENTLLVYSFSKYFGATGWRLGVVAAHQQNVFDLALDKLQESEKVALDHRYRSLLPDVRSL 364 Query: 305 SNGFPIINDFHRIVTTSFNGASNIAQA----GGLACLSSGGLKEIRSVNNYYKENRKILM 360 ++ D + G S Q L L + ++ + L Sbjct: 365 KFIDRLVADSRAVALNHTAGLSTPQQVQMALFSLFALMDEADEYKHTLKQLIRRRETTLY 424 Query: 361 DTLVSLGLKVYGGVNAPYLWVHFKGSKSW---DVFNEI--------------LENTHIIT 403 L L+ V+ Y + + + + F+E + T I+ Sbjct: 425 RELGMPPLRDENAVD-YYTLIDLQDVTAKLYGEAFSEWAVKQSSTGDMLFRIADETGIVL 483 Query: 404 VPGSGFGPGGEEYLRISGFGRRDHIVEASKR-LQNFFNTRTKHFT 447 +PG GFG R S ++ A R L+ + ++ Sbjct: 484 LPGRGFGSNRPSG-RASLANLNEYEYAAIGRALRKMADELYAEYS 527 >3EUC-A nrPDB Length = 367 Score = 112 bits (281), Expect = 2e-25, Method: Composition-based stats. Identities = 56/373 (15%), Positives = 117/373 (31%), Gaps = 41/373 (10%) Query: 59 RELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLR 118 R + + L+ L + +P + S ++ ++ Y + Sbjct: 19 RAMGAYHVPDSHGLVKLDAMENPYRLPPALRSELAARLGEVAL----NRYPVPS-----S 69 Query: 119 KAIAETFYRDLHVKSN-EVFVSDGAQSDISRL-QLLLGSNVTIAVQDPTFPAYIDSSVII 176 +A+ + V + EV + +G+ IS L + P F Y S+ Sbjct: 70 EALRAKLKEVMQVPAGMEVLLGNGSDEIISMLALAAARPGAKVMAPVPGFVMYAMSAQFA 129 Query: 177 GQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQ 236 G + P +++ PNNPTG + + Sbjct: 130 GLEFVGVPLRADFTLDRGAMLAAMAEHQPA--------IVYLAYPNNPTGNLFDAADMEA 181 Query: 237 LVDFAKTNGS--IIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLG 294 +V A+ + +++ D AY F ++ S + + + SK G G+RLG Sbjct: 182 IVRAAQGSVCRSLVVVDEAYQPFAQE----SWMSRLTDFGNLLVMRTVSK-LGLAGIRLG 236 Query: 295 WSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKE 354 + + L V +N + + +A L L + + + Sbjct: 237 YVAGDPQWLEQLDK---------VRPPYN-VNVLTEATALFALEHVAV--LDEQAAQLRA 284 Query: 355 NRKILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSWDVFNEILENTHIITVPGSGFGPGGE 414 R + + + + G A +L + F+ +L ++ S P Sbjct: 285 ERSRVAEGMAAHGGVTVFPSAANFLLARVPDAAQT--FDRLLAR-KVLIKNVSKMHPLLA 341 Query: 415 EYLRISGFGRRDH 427 LR++ ++ Sbjct: 342 NCLRVTVSTPEEN 354 >3FDD-A nrPDB Length = 533 Score = 110 bits (274), Expect = 2e-24, Method: Composition-based stats. Identities = 66/405 (16%), Positives = 126/405 (31%), Gaps = 76/405 (18%) Query: 108 YGLEQGNKTLRKAIAETF------YRDLHVKSNEVFVSDGAQSDISRL------QLLLGS 155 Y + + + I + + +S +F +G + ++ + LL + Sbjct: 134 YPVPPRMLNISEKIVRQYIIREMGADAIPSESVNLFAVEGGTAAMAYIFESMKVNGLLKA 193 Query: 156 NVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDV 215 +A+ P F YI+ + + E+ + P++ D P + Sbjct: 194 GDKVAIGMPVFTPYIEIPELA---QYALEEVAINADPALNWQYPDSE--LDKLKDPAIKI 248 Query: 216 IFFCSPNNPTGYVASRKQLHQLVDFAKTN--GSIIIFDSAYAAFIEDGSPRSIYEIPGAR 273 F +P+NP + L ++ + +I+ D Y F + +S++ I A Sbjct: 249 FFCVNPSNPPSVKMDERSLERVRKIVAEHRPDLMILTDDVYGTFADG--FQSLFAICPA- 305 Query: 274 EVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNG-------------------------- 307 + V SFSK+ G TG RLG E ++ Sbjct: 306 -NTLLVYSFSKYFGATGWRLGVVAAHKENIFDLALGRLPESEKTALDDRYRSLLPDVRSL 364 Query: 308 ---FPIINDFHRIVTTSFNGASNIAQA----GGLACLSSGGLKEIRSVNNYYKENRKILM 360 ++ D + G S Q L L + ++ + L Sbjct: 365 KFLDRLVADSRAVALNHTAGLSTPQQVQMTLFSLFALMDESDQYKHTLKQLIRRREATLY 424 Query: 361 DTLVSLGLKVYGGVNAPYLWVHFKGSKSW-----------------DVFNEILENTHIIT 403 L + + V+ Y + + S D+ I + T I+ Sbjct: 425 RELGTPPQRDENAVD-YYTLIDLQDVTSKLYGEAFSKWAVKQSSTGDMLFRIADETGIVL 483 Query: 404 VPGSGFGPGGEEYLRISGFGRRDHIVEASKR-LQNFFNTRTKHFT 447 +PG GFG R S ++ A R L+ + +T Sbjct: 484 LPGRGFGSDRPSG-RASLANLNEYEYAAIGRALRQMADELYAQYT 527 >2ZY2-A nrPDB Length = 544 Score = 107 bits (268), Expect = 9e-24, Method: Composition-based stats. Identities = 69/410 (16%), Positives = 128/410 (31%), Gaps = 89/410 (21%) Query: 108 YGLEQGNKTLRKAIAETF------YRDLHVKSNEVFVSDGAQSDIS------RLQLLLGS 155 Y + T+ + I + + +S ++F +G + ++ R+ LL + Sbjct: 133 YPVPPRMLTVSEQIVRQYIVREMAGGAVPPESVDLFAVEGGTAAMAYIFESLRISGLLKA 192 Query: 156 NVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFF-----PDLAMT 210 +A+ P F YI+ + + V + P+N + D Sbjct: 193 GDKVAIGMPVFTPYIEIPELA----------QYDLKEVPIHADPDNGWQYSDAELDKLKD 242 Query: 211 PRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTN--GSIIIFDSAYAAFIEDGSPRSIYE 268 P + F +P+NP ++ L ++ +I+ D Y F ++ +S++ Sbjct: 243 PDVKIFFCVNPSNPPSVKMDQRSLDRVRAIVAEQRPDLLILTDDVYGTFADE--FQSLFS 300 Query: 269 IPGAREVAIEVSSFSKFAGFTGVRLGWSII-----------------------------P 299 + + V SFSK+ G TG RLG P Sbjct: 301 V--CPRNTLLVYSFSKYFGATGWRLGVIAAHKDNVFDHALSQLPESAKKALDHRYRSLLP 358 Query: 300 DELLYSNGFPIINDFHRIVTTSFNGASNIAQA----GGLACLSSGGLKEIRSVNNYYKEN 355 D ++ D + G S Q L L +++ + Sbjct: 359 DVRSLKFIDRLVADSRVVALNHTAGLSTPQQVQMVLFSLFALMDEADAYKQALKQLIRRR 418 Query: 356 RKILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSW---DVFNEI--------------LEN 398 L L L+ VN Y + + + F++ + Sbjct: 419 EATLYRELGMPPLENPNSVN-YYTLIDLQNVTCRLYGEAFSQWAVQQSSTGDMLFRVADE 477 Query: 399 THIITVPGSGFGPGGEEYLRISGFGRRD----HIVEASKRLQNFFNTRTK 444 T I+ +PG GFG R S + I A +RL + + K Sbjct: 478 TGIVLLPGRGFGSDRPSG-RASLANLNEYEYAAIGRALRRLADELYEQYK 526 >3G0T-A nrPDB Length = 437 Score = 106 bits (265), Expect = 2e-23, Method: Composition-based stats. Identities = 66/368 (17%), Positives = 121/368 (32%), Gaps = 49/368 (13%) Query: 64 IEKHPNVQLISLGTGDTTEPIPEQ-ITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIA 122 +EK + + G P P+ I + + G++++ Y G L++ + Sbjct: 38 LEKATGTKFCRMEMGVPGLPAPQIGIETEIQKLREGVASI-----YPNLDGLPELKQEAS 92 Query: 123 ET--FYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVT-------IAVQDPTFPAYIDSS 173 + ++ + + + G+ L +N T DP F Sbjct: 93 RFAKLFVNIDIPARACVPTVGSMQG--CFVSFLVANRTHKNREYGTLFIDPGFNLNKLQC 150 Query: 174 VIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQ 233 I+GQ + + + T + I + +PNNPT + ++ Sbjct: 151 RILGQKFESFDLFEYRGEKLR-------EKLESYLQTGQFCSIIYSNPNNPTWQCMTDEE 203 Query: 234 LHQLVDFAKTNGSIIIFDSAY------AAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAG 287 L + + A + I+I D AY + G P + + I S SK Sbjct: 204 LRIIGELATKHDVIVIEDLAYFGMDFRKDYSHPGEPLYQPSVANYTDNYILALSSSKAFS 263 Query: 288 FTGVRLGWSIIPDELLYSNGFPIINDFHRIV----------TTSFNGASNIAQAGGLACL 337 + G R+G +I +L + F R+ +GA++ AQ G A L Sbjct: 264 YAGQRIGVLMISGKLYEREYPDLEESFGRLRFGEALSSSALYALSSGATHSAQWGMAAML 323 Query: 338 S--SGGLKEIRSVNNYYKENRKILMDTLVSLGLK-VYGGVN------APYLWVHFKGSKS 388 + G R Y +I+ + G VY Y V +KG S Sbjct: 324 KACNDGEYNFRDSVIEYGRKARIMKKMFLDNGFNIVYDKDGNEPLADGFYFTVGYKGMDS 383 Query: 389 WDVFNEIL 396 + + + Sbjct: 384 SKLIEKFV 391 >4EMY-A nrPDB Length = 413 Score = 104 bits (260), Expect = 6e-23, Method: Composition-based stats. Identities = 73/410 (17%), Positives = 132/410 (32%), Gaps = 40/410 (9%) Query: 55 EINRRELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGN 114 +IN + IEK+ +I+ G + + I Y +G Sbjct: 22 DINNKANAAIEKYGREAVINAALGTLLDDKGKIIALPSVYDRLDEMDRSHIASYAPIEGE 81 Query: 115 KTLRKAIAETFYRDLHVKSN---EVFVSDGAQSDI-SRLQLLLGSNVTIAVQDPTFPAYI 170 K RK + +T + K + G I S + L + D + Y Sbjct: 82 KDYRKIVIDTLFG--PYKPEGYISAIATPGGTGAIRSAIFSYLDEGDPLICHDYYWAPYR 139 Query: 171 DSSVIIG---QTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSP-NNPTG 226 G +T F + VY D + SP NNPTG Sbjct: 140 KICEEFGRNFKTFEFFTDDFAFNIDVYKEAIDEGIRDSDRIAS------LINSPGNNPTG 193 Query: 227 YVASRKQLHQLVDFA------KTNGSIIIFDSAYAAFIEDG----SPRSIYEIPGAREVA 276 Y S ++ +++ F K +I D AY F DG + Sbjct: 194 YSLSDEEWDEVITFLKEKAEDKDKKITLIVDVAYLEFAGDGDQQRKFFEKFSNLPRNLFV 253 Query: 277 IEVSSFSKFAGFTGVRLGWSII---PDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGG 333 + S SK G+R G ++ E++ + + + + A NI Sbjct: 254 VVAFSMSKSHTAYGLRSGAAVGISSSKEIIEEFEASLAHSARCNWSNGTHAAQNILIELE 313 Query: 334 LACLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSWDVFN 393 A +E+ + N K + + L + + ++ K++D+ Sbjct: 314 RAENKKIYEQELVDLRNMLKSRADVFVTAAKENKLTMIPYFGGFFTFI--PTDKAFDIVK 371 Query: 394 EILENTHIITVPGSGFGPGGEEYLRISGFG-RRDHIVEASKRLQNFFNTR 442 + LE +I T+P + +R++ G + I + +RL + N + Sbjct: 372 D-LEKENIFTIP-------SAKGIRVAICGVGEEKIPKLVQRLAFYTNKK 413 >3F6T-A nrPDB Length = 533 Score = 103 bits (257), Expect = 2e-22, Method: Composition-based stats. Identities = 69/412 (16%), Positives = 118/412 (28%), Gaps = 84/412 (20%) Query: 106 RGYGLEQGNKTLRKAIAETFYRDLHVKS------NEVFVSDGAQSDI------SRLQLLL 153 Y + + I F ++L K ++F ++G + I LL Sbjct: 131 NNYPVPDRCLVNTEKIINYFLQELSYKDANLAEQTDLFPTEGGTAAIVYAFHSLAENHLL 190 Query: 154 GSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRT 213 IA+ +P F Y+ + + E PN + P Sbjct: 191 KKGDKIAINEPIFTPYLRIPEL--KDYELVEVDLHSYEKNDWEIEPNE---IEKLKDPSI 245 Query: 214 DVIFFCSPNNPTGYVASRKQLHQLVDFAKTNG-SIIIFDSAYAAFIEDGSPRSIYEIPGA 272 + +P NPT L+ + + N +II D Y AF+ + +SIY + Sbjct: 246 KALIVVNPTNPTSKEFDTNALNAIKQAVEKNPKLMIISDEVYGAFV--PNFKSIYSVVP- 302 Query: 273 REVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNG------------------------- 307 + V S+SK G TG RLG + ++ ++ + Sbjct: 303 -YNTMLVYSYSKLFGCTGWRLGVIALNEKNVFDDNIAHLDKVELRQLHKRYSSVVLDPDK 361 Query: 308 ----FPIINDFHRIVTTSFNGASNIAQAGGLACL---------SSGGLK--EIRSVNNYY 352 + D I G S Q + L ++GG I Sbjct: 362 MKFIDRLCADSRSIGLYHTAGLSTPQQI--MEALFSMTHLLTSTNGGSDDPYIDIARKLV 419 Query: 353 KENRKILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSW-----------------DVFNEI 395 E L D + + Y + D ++ Sbjct: 420 SERYDQLHDAMQAPK-DETDTNTHYYSLIDIYRLAEKIYGKEFRDYLTNNFEQVDFLLKL 478 Query: 396 LENTHIITVPGSGFGPGGEEYLRISGFG-RRDHIVEASKRLQNFFNTRTKHF 446 E ++ V G GFG LR+S + K++ + F Sbjct: 479 AEKNGVVLVDGVGFGAK-PGELRVSQANLPTEDYALIGKQVLELLKEYYEEF 529 >3RQ1-A nrPDB Length = 418 Score = 102 bits (253), Expect = 4e-22, Method: Composition-based stats. Identities = 60/325 (18%), Positives = 104/325 (32%), Gaps = 31/325 (9%) Query: 101 TVEGYRGYGLEQGNKTLRKAIAE----TFYRDLHVKSNEVFVSDGAQSDISRLQ-LLLGS 155 + + GY G A + F + H++S + G I L Sbjct: 69 SDSEHVGYAPIAGIPDFLCAAEKECFGNFRPEGHIRS---IATAGGTGGIHHLIHNYTEP 125 Query: 156 NVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDV 215 + D + AY G+T + ++ N + + +LA V Sbjct: 126 GDEVLTADWYWGAYRVICSDTGRTLVTYSLFDEHNNFNHEAF---QNRVNELAAKQTNVV 182 Query: 216 IFFCSP-NNPTGYVASRKQLHQLVDFAK------TNGSIIIFDSAYAAFIEDGSPRSIY- 267 + F +P NNPTGY K +++F K N II D AY + + + Sbjct: 183 VIFNTPGNNPTGYSIEDKDWDSILNFLKDLVAIGRNNVIIGIDVAYLDYSGEKDEVRAFF 242 Query: 268 ---EIPGAREVAIEVSSFSKFAGFTGVRLGWSII-PDELLYSNGFPIINDFHRIVTTSFN 323 + S SK G R+G I D+ ++ F +N T S Sbjct: 243 NKFSHLPKEILTCVCYSLSKGFTMYGQRVGAMIGISDDEEIADEFFEVNKSTSRATWSNI 302 Query: 324 GASNIAQAGGLACLSSGGLKEIRSVNNYY----KENRKILMDTLVSLGLKVYGGVNAPYL 379 + + KE + N Y ++ I +GL + ++ Sbjct: 303 CRPAMRTMANIVA-DPAKFKEYEAERNCYYQLIRDRADIFKQEAAQVGLPMLPYRGGFFI 361 Query: 380 WVHFKGSKSWDVFNEILENTHIITV 404 + + S + E L+ HI + Sbjct: 362 TI---PTDSANAICEELKKEHIYVI 383 >5X03-B nrPDB Length = 365 Score = 100 bits (250), Expect = 9e-22, Method: Composition-based stats. Identities = 67/355 (18%), Positives = 125/355 (35%), Gaps = 49/355 (13%) Query: 109 GLEQGNKTLRKAIAET--FYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQDPTF 166 QG +R AI R + + ++ + G Q + L LL A+++P + Sbjct: 39 SHPQGIYEVRAAITRLISLTRGVKCRPEQMIIGAGTQVLMQLLTELLPKEAVYAMEEPGY 98 Query: 167 PAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNN--P 224 G+ +K ++ + PD + +P++ P Sbjct: 99 RRMYQLLKNAGKQVKTIMLDEKGMSIAEI-----TRQQPD---------VLVTTPSHQFP 144 Query: 225 TGYVASRKQLHQLVDFAKTNGSIIIFDSAY-AAFIEDGSPRSIYEIPGAREVAIEVSSFS 283 +G + + QL+++A I + Y + F D + + I + +FS Sbjct: 145 SGTIMPVSRRIQLLNWAAEEPRRYIIEDDYDSEFTYDVDSIPALQSLDRFQNVIYMGTFS 204 Query: 284 KFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGG-L 342 K G+R+ + ++P ELL ++ S++ Q + SG Sbjct: 205 KSL-LPGLRISYMVLPPELL---------RAYKQRGYDLQTCSSLTQLTLQEFIESGEYQ 254 Query: 343 KEIRSVNNYYKENRKILMDTLVS--LGLKVYGGVNAPYLWVHFKGSKSWDVFNEILENTH 400 K I+ + +YKE R+ L+ L + G G NA +V + +IL +H Sbjct: 255 KHIKKMKQHYKEKRERLITALEAEFSGEVTVKGANAGLHFV--TEFDTRRTEQDIL--SH 310 Query: 401 IITVPGSGFG-----------PGGEEYLRISGFG-RRDHIVEASKRL-QNFFNTR 442 + FG G L I + + I E +RL + + R Sbjct: 311 AAGLQLEIFGMSRFNLKENKRQTGRPALIIGFARLKEEDIQEGVQRLFKAVYGHR 365 >4N0B-A nrPDB Length = 479 Score = 100 bits (249), Expect = 1e-21, Method: Composition-based stats. Identities = 66/347 (19%), Positives = 122/347 (35%), Gaps = 48/347 (13%) Query: 109 GLEQGNKTLRKAIAET--FYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQDPTF 166 QG +R AI R + + ++ + G Q + L LL A+++P + Sbjct: 146 SHPQGIYEVRAAITRLISLTRGVKCRPEQMIIGAGTQVLMQLLTELLPKEAVYAMEEPGY 205 Query: 167 PAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNN--P 224 G+ +K ++ + PD + +P++ P Sbjct: 206 RRMYQLLKNAGKQVKTIMLDEKGMSIAEI-----TRQQPD---------VLVTTPSHQFP 251 Query: 225 TGYVASRKQLHQLVDFAKTNGSIIIFDSAY-AAFIEDGSPRSIYEIPGAREVAIEVSSFS 283 +G + + QL+++A I + Y + F D + + I + +FS Sbjct: 252 SGTIMPVSRRIQLLNWAAEEPRRYIIEDDYDSEFTYDVDSIPALQSLDRFQNVIYMGTFS 311 Query: 284 KFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGG-L 342 K G+R+ + ++P ELL ++ S++ Q + SG Sbjct: 312 KSL-LPGLRISYMVLPPELL---------RAYKQRGYDLQTCSSLTQLTLQEFIESGEYQ 361 Query: 343 KEIRSVNNYYKENRKILMDTLVS--LGLKVYGGVNAPYLWVHFKGSKSWDVFNEILENTH 400 K I+ + +YKE R+ L+ L + G G NA +V + +IL +H Sbjct: 362 KHIKKMKQHYKEKRERLITALEAEFSGEVTVKGANAGLHFV--TEFDTRRTEQDIL--SH 417 Query: 401 IITVPGSGFG-----------PGGEEYLRISGFG-RRDHIVEASKRL 435 + FG G L I + + I E +RL Sbjct: 418 AAGLQLEIFGMSRFNLKENKRQTGRPALIIGFARLKEEDIQEGVQRL 464 >6C3C-A nrPDB Length = 413 Score = 100 bits (248), Expect = 2e-21, Method: Composition-based stats. Identities = 59/400 (14%), Positives = 130/400 (32%), Gaps = 44/400 (11%) Query: 68 PNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRG------YGLEQGNKT----- 116 P L+ L + + + ++ + Y E+G + Sbjct: 29 PGAPLLDLTQHEIQALTMKYNLADAHTHQRQSASQQSIVSRLPQLWYEAEEGLQATYEKR 88 Query: 117 LRKAIAETFYRDLHVKSNEVFVSDGAQSD-ISRLQLLLGSNVTIAVQDPTFPAYIDSSVI 175 +A + + + N+ +S A + L + + + +P F D Sbjct: 89 FTEAFFQLHRQPTALVKNKTMLSYAASISTMVAGMFLKKERLAVTLIEPCFDNLYDVLAN 148 Query: 176 IGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVA---SRK 232 + + +++ Y + +P+L RTD +F PNNPTG+ RK Sbjct: 149 MDVPLYPIDESVFYDV---------DRIYPELERRVRTDALFLVDPNNPTGFSLLRHGRK 199 Query: 233 QLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVA----IEVSSFSKFAGF 288 ++V F K + +++ D +A+F + +++ E + + + K Sbjct: 200 GFEEVVRFCKDHDKLLLIDFCFASFTLFEPELARFDMYELLENSGVRYLAIEDTGKTWPV 259 Query: 289 TGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSV 348 + D++ + + + T+ S + + SV Sbjct: 260 QDAKCALITASDDIWET--------VYNLHTSVLLNVSPFVLNMLTQYVRDSAADRLASV 311 Query: 349 NNYYKENRKILMDTLVSLGLKVYGG---VNAPYLWVHFKGSKSWDVFNEILENTHIITVP 405 NR+ TL L+ V+ + V + DV + +L + +P Sbjct: 312 REVLTRNRECARKTLDGSILEYQEPVVKVSVAWFRVDHPELTATDV-HRLLSADGVYVLP 370 Query: 406 GSGF----GPGGEEYLRISGFGRRDHIVEASKRLQNFFNT 441 G F G+ Y+R++ + +A + + Sbjct: 371 GRYFYWSEPSKGDAYVRMALAREPEMFADAMALTRQVLDR 410 >4F5M-A nrPDB Length = 406 Score = 97.5 bits (241), Expect = 1e-20, Method: Composition-based stats. Identities = 64/384 (16%), Positives = 123/384 (32%), Gaps = 38/384 (9%) Query: 44 LEKLKNNYLFPEINRRELEHIEKHPNVQLISLGTG---DTTEPIPEQITSHMSNFAHGLS 100 E + P + +L ++ P I+LG G D T P + + + L Sbjct: 12 FENITAAPADPILGLADLFRADERPGK--INLGIGVYKDETGKTP--VLTSVKKAEQYLL 67 Query: 101 TVEGYRGYGLEQGNKTL-RKAIAETFYRDLHVKSN---EVFVSDGAQSDISRLQLLLGSN 156 E + Y G R F + + ++ + G + L N Sbjct: 68 ENETTKNYLGIDGIPEFGRCTQELLFGKGSALINDKRARTAQTPGGTGALRVAADFLAKN 127 Query: 157 V---TIAVQDPTFPAYIDSSVIIGQTGH---FHEKTKKYQNVVYMPCGPNNSFFPDLAMT 210 + V +P++P + G +++ + + N + D+ Sbjct: 128 TSVKRVWVSNPSWPNHKSVFNSAGLEVREYAYYDAENHTLDFDALINSLNEAQAGDV--- 184 Query: 211 PRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIE--DGSPRSIYE 268 V+F +NPTG + +Q L + G + +FD AY F + + Sbjct: 185 ----VLFHGCCHNPTGIDPTLEQWQTLAQLSVEKGWLPLFDFAYQGFARGLEEDAEGLRA 240 Query: 269 IPGAREVAIEVSSFSKFAGFTGVRLGW--SIIPDELLYSNGFPIINDFHR--IVTTSFNG 324 + I SS+SK G R+G + D F + R +G Sbjct: 241 FAAMHKELIVASSYSKNFGLYNERVGACTLVAADSETVDRAFSQMKAAIRANYSNPPAHG 300 Query: 325 ASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILMDTLVSLG----LKVYGGVNAPYLW 380 AS +A L + +E+ + + R++ ++TL G N + + Sbjct: 301 ASVVATILSNDALRAIWEQELTDMRQRIQRMRQLFVNTLQEKGANRDFSFIIKQNGMFSF 360 Query: 381 VHFKGSKSWDVFNEILENTHIITV 404 + + + E + V Sbjct: 361 SGL----TKEQVLRLREEFGVYAV 380 >1AY8-A nrPDB Length = 394 Score = 97.1 bits (240), Expect = 2e-20, Method: Composition-based stats. Identities = 61/317 (19%), Positives = 108/317 (34%), Gaps = 25/317 (7%) Query: 66 KHPNVQLISLGTG---DTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIA 122 P I LG G D T P I + + E + Y G +KA+ Sbjct: 22 ADPRQGKIDLGVGVYKDATGHTP--IMRAVHAAEQRMLETETTKTYAGLSGEPEFQKAMG 79 Query: 123 ET-FYRDLHVKSNEVFVSDGAQSDISR---LQLLLGSNVTIAVQDPTFPAYIDSSVIIGQ 178 E L ++ + G + + L + ++ + V DPT+P ++ +G Sbjct: 80 ELILGDGLKSETTATLATVGGTGALRQALELARMANPDLRVFVSDPTWPNHVSIMNFMGL 139 Query: 179 TGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFF--CSPNNPTGYVASRKQLHQ 236 + V DLA + D++ C +NPTG + Q + Sbjct: 140 PVQTYRYFDAETRGVDF-----EGMKADLAAAKKGDMVLLHGCC-HNPTGANLTLDQWAE 193 Query: 237 LVDFAKTNGSIIIFDSAYAAF---IEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRL 293 + + G++ + D AY F +E+ + + EV I +S SK G R Sbjct: 194 IASILEKTGALPLIDLAYQGFGDGLEEDAAGTRLIASRIPEVLIA-ASCSKNFGIYRERT 252 Query: 294 GWSII----PDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVN 349 G + + G + F+GA ++ L + + E+ +V Sbjct: 253 GCLLALCADAATRELAQGAMAFLNRQTYSFPPFHGAKIVSTVLTTPELRADWMAELEAVR 312 Query: 350 NYYKENRKILMDTLVSL 366 + R+ L L L Sbjct: 313 SGMLRLREQLAGELRDL 329 >3FSL-A nrPDB Length = 397 Score = 95.6 bits (236), Expect = 4e-20, Method: Composition-based stats. Identities = 64/358 (17%), Positives = 110/358 (30%), Gaps = 31/358 (8%) Query: 61 LEHIEKHPNVQLISLGTG---DTTEPIPEQITSHMSNFAHGLS-TVEGYRGYGLEQGNKT 116 +E ++ P ++L G + IP+ ++ L+ G Y +G Sbjct: 17 MERFKEDPRSDKVNLSIGLYYNEDGIIPQ--LQAVAEAEARLNAQPHGASLYLPMEGLNC 74 Query: 117 LRKAIAETFYRDLH--VKSNEV--FVSDGAQSDISRLQLLLG---SNVTIAVQDPTFPAY 169 R AIA + H +K V + G + L + V DPT+ + Sbjct: 75 YRHAIAPLLFGADHPVLKQQRVATIQTLGGSGALKVGADFLKRYFPESGVWVSDPTWENH 134 Query: 170 IDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFF--CSPNNPTGY 227 + G + + N V N L ++ C +NPTG Sbjct: 135 VAIFAGAGFEVSTYPWYDEATNGVRF-----NDLLATLKTLQAGSIVLLHPCC-HNPTGA 188 Query: 228 VASRKQLHQLVDFAKTNGSIIIFDSAYAAFIE--DGSPRSIYEIPGAREVAIEVSSFSKF 285 + Q +++ K I D AY F + +I I A A+ +SFSK Sbjct: 189 DLTNDQWDAVIEILKARELIPFLDIAYQGFGAGMEEDAYAIRAIASAGLPALVSNSFSKI 248 Query: 286 AGFTGVRLG---WSIIPDELLYSNGFPIINDFHR-IVTTSFNGASNIAQAGGLACLSSGG 341 G R+G E + R + GA +A L + Sbjct: 249 FSLYGERVGGLSVMCEDAEAAGRVLGQLKATVRRNYSSPPNFGAQVVAAVLNDEALKASW 308 Query: 342 LKEIRSVNNYYKENRKILMDTL----VSLGLKVYGGVNAPYLWVHFKGSKSWDVFNEI 395 LKE+ + R+ L+ L + + ++ + E Sbjct: 309 LKEVEEMRTRILAMRQELVKVLSTEMPERNFDYLLNQRGMFSYTGLSAAQVDRLREEF 366 >3BWN-A nrPDB Length = 391 Score = 94.8 bits (234), Expect = 7e-20, Method: Composition-based stats. Identities = 62/353 (17%), Positives = 121/353 (34%), Gaps = 69/353 (19%) Query: 115 KTLRKAIAETFY--RDLHVKSNEVFVSDGAQS----DISRLQLLLGSNV-TIAVQDPTFP 167 L AI + + + + V G+ + L L S ++ P + Sbjct: 71 PELEDAIKDLHGVVGNAATEDRYIVVGTGSTQLCQAAVHALSSLARSQPVSVVAAAPFYS 130 Query: 168 AYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGY 227 Y++ +T ++ +Y G F + SPNNP G Sbjct: 131 TYVE-------------ETTYVRSGMYKWEGDAWGFDKK-----GPYIELVTSPNNPDGT 172 Query: 228 VASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAG 287 + +V+ + + +I D AY + +P I ++ I + +FSK G Sbjct: 173 I-----RETVVNRPDDDEAKVIHDFAY--YWPHYTP-----ITRRQDHDIMLFTFSKITG 220 Query: 288 FTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLS--SGGLKEI 345 G R+GW+++ D+ + + + G S +Q L+ K Sbjct: 221 HAGSRIGWALVKDK-------EVAKKMVEYIIVNSIGVSKESQVRTAKILNVLKETCKSE 273 Query: 346 RSVNNYYKENRKILMDTLVSLGLKVYGGVNAPYL-----------------WVHFKG--- 385 N++K R+++ + L +V +A L + F Sbjct: 274 SESENFFKYGREMMKNRWEKLR-EVVKESDAFTLPKYPEAFCNYFGKSLESYPAFAWLGT 332 Query: 386 SKSWDVFNEILENTHIITVPGSGFGPGGEEYLRISGFGRRDHIVEASKRLQNF 438 + D+ +E L +++ G G ++++R+S R D +RL N Sbjct: 333 KEETDLVSE-LRRHKVMSRAGERCGSD-KKHVRVSMLSREDVFNVFLERLANM 383 >4WD2-A nrPDB Length = 408 Score = 93.7 bits (231), Expect = 1e-19, Method: Composition-based stats. Identities = 53/319 (16%), Positives = 97/319 (30%), Gaps = 18/319 (5%) Query: 62 EHIEKHPNVQLISLGTGD-TTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKA 120 E+ +K P Q ++L G + + L G + Y G R A Sbjct: 26 ENFQKDPRDQKVNLSIGIYFDAEGRIPVMGAVREAETALQRDSGPKPYLPMVGLAAYRDA 85 Query: 121 IAETFYRDLHVKSNE----VFVSDGAQSDISRLQLLLG---SNVTIAVQDPTFPAYIDSS 173 + + H + G + L + + + DP++ + Sbjct: 86 VQSLVFGADHPARAAGRIATLQTLGGSGALKVGADFLKRYFPDSQVWLSDPSWENHRFIF 145 Query: 174 VIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQ 233 G T + + + + A+ R+ V+ +NPTG Q Sbjct: 146 ERAGFTVNTYPYYDEATGGLKFDAMLAAID----ALPARSIVLLHACCHNPTGVDLDEGQ 201 Query: 234 LHQLVDFAKTNGSIIIFDSAYAAFIE--DGSPRSIYEIPGAREVAIEVSSFSKFAGFTGV 291 +L+D + + D AY F D ++ E+ + +SFSK G Sbjct: 202 WEKLIDVIEARELLPFVDMAYQGFGAGLDADAFAVRELARRGVPTLVANSFSKNFSLYGE 261 Query: 292 RLG--WSIIPDELLYSNGFPIINDFHR--IVTTSFNGASNIAQAGGLACLSSGGLKEIRS 347 R+G + D + R GA +A G L +E+ + Sbjct: 262 RVGGLSVVCEDAAAAERVLGQLAGAVRSNYSNPQTYGAKVVAAVLGTPALRKQWEEELSA 321 Query: 348 VNNYYKENRKILMDTLVSL 366 + R+ + D L Sbjct: 322 MCRRIARMRQSIHDGLRDH 340 >4WBT-A nrPDB Length = 376 Score = 92.1 bits (227), Expect = 5e-19, Method: Composition-based stats. Identities = 52/390 (13%), Positives = 119/390 (30%), Gaps = 46/390 (11%) Query: 42 VNLEKLKNNYLFPEINRRELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLST 101 ++ L + F E +H K +G ++ + + A Sbjct: 12 PLIQSLPASVPFVGPEALERQHGRKI----AARIGANESGFGPAPSVLLAIRQAA----- 62 Query: 102 VEGYRGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRLQLLL-GSNVTIA 160 Y + + L++A+A R L + + +G + ++ L+ + + Sbjct: 63 -GDTWKYADPENHD-LKQALA----RHLGTSPANIAIGEGIDGLLGQIVRLVVEAGAPVV 116 Query: 161 VQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCS 220 +P + G +++ + P +++ + Sbjct: 117 TSLGGYPTFNYHVAGHGGRLVTVPYADDREDLEGLLAAVGRENAP---------LVYLAN 167 Query: 221 PNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVS 280 P+NP G +++ ++++ D AY + I + + I Sbjct: 168 PDNPMGSWWPAERVVAFAQALPET-TLLVLDEAYCETAPRDALPPIESLID-KPNVIRAR 225 Query: 281 SFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSG 340 +FSK G G R+G+++ P + F G S I A + Sbjct: 226 TFSKAYGLAGARIGYTL---------STPGTAQAFDKIRNHF-GMSRIG--VAAAIAALA 273 Query: 341 GLKEIRSVNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHF--KGSKSWDVFNEILEN 398 ++ V +R+ + GL ++ V S + + + ++ + Sbjct: 274 DQDYLKEVTLKIANSRQRIGRIAADSGLAPL-PSATNFVAVDCGKDASYARAIVDRLMSD 332 Query: 399 THIIT-VPGSGFGPGGEEYLRISGFGRRDH 427 I +PG +RIS + Sbjct: 333 HGIFIRMPGVA---PLNRCIRISTAPDAEM 359 >2X5F-A nrPDB Length = 430 Score = 91.0 bits (224), Expect = 1e-18, Method: Composition-based stats. Identities = 47/355 (13%), Positives = 109/355 (30%), Gaps = 40/355 (11%) Query: 94 NFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYRDLH----VKSNEVFVSDGAQSDISRL 149 + T + Y QG + LR + RD + V++ +S + Sbjct: 70 DAMFNDLTPDEIFPYAPPQGIEELRDLWQQKMLRDNPELSIDNMSRPIVTNALTHGLSLV 129 Query: 150 -QLLLGSNVTIAVQDPTFPAYIDSSVIIGQ----TGHFHEKTKKYQNVVYMPCGPNNSFF 204 L + + TI + + + Y T +K Y + + + Sbjct: 130 GDLFVNQDDTILLPEHNWGNYKLVFNTRNGANLQTYPIFDKDGHYTTDSLVEALQSYNKD 189 Query: 205 PDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKT-----NGSIIIFDSAYAAFIE 259 ++ PNNPTGY + K++ +V+ K I + D AY Sbjct: 190 K--------VIMILNYPNNPTGYTPTHKEVTTIVEAIKALANKGTKVIAVVDDAYYGLFY 241 Query: 260 DG-----SPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDF 314 + ++ + + I + +K G R+G+ + + Sbjct: 242 EDVYTQSLFTALTNLHSNAILPIRLDGATKEFFAWGFRVGFMTFGTSDQTTKEV-LEAKV 300 Query: 315 HRIVTTSFNGASNIAQAGGLACLSSGGL--KEIRSVNNYYKENRKILMDTLVS----LGL 368 ++ ++ + Q+ L + KEI KE ++ + + + Sbjct: 301 KGLIRSNISSGPLPTQSAVKHVLKNNKQFDKEIEQNIQTLKERYEVTKEVVYADQYHSHW 360 Query: 369 KVYGGVNAPYLWVHFKGSKSWDVFNEILENTHIITVPGSGFGPGGEEYLRISGFG 423 + Y + ++ + + +++ I + + +RI+ Sbjct: 361 QAYDFNSGYFMAIKVHDVDPEALRKHLIDKYSIGVIALNATD------IRIAFSC 409 >3PD6-B nrPDB Length = 401 Score = 87.9 bits (216), Expect = 7e-18, Method: Composition-based stats. Identities = 55/355 (15%), Positives = 106/355 (29%), Gaps = 26/355 (7%) Query: 62 EHIEKHPNVQLISLGTGDT-TEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKA 120 E ++ N + ++LG G + + + ++ + Y G KA Sbjct: 20 EAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYLPIGGLAEFCKA 79 Query: 121 IAET--------FYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDS 172 AE V + + + S LQ + + + P++ + Sbjct: 80 SAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFLPKPSWGNHTPI 139 Query: 173 SVIIG-QTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASR 231 G Q + K + + S P+ ++ ++ +NPTG Sbjct: 140 FRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSV-----LLLHACAHNPTGVDPRP 194 Query: 232 KQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAI---EVSSFSKFAGF 288 +Q ++ K FD AY F + + + E I S++K G Sbjct: 195 EQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGL 254 Query: 289 TGVRLGW--SIIPDELLYSNGFPIINDFHR--IVTTSFNGASNIAQAGGLACLSSGGLKE 344 G R+G + D + R NGA A L L+E Sbjct: 255 YGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATILTSPDLRKQWLQE 314 Query: 345 IRSVNNYYKENRKILMDTLVSLG----LKVYGGVNAPYLWVHFKGSKSWDVFNEI 395 ++ + + R L+ L G + + + K + + E Sbjct: 315 VKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPEQVERLTKEF 369 >1YAA-A nrPDB Length = 412 Score = 86.3 bits (212), Expect = 2e-17, Method: Composition-based stats. Identities = 71/431 (16%), Positives = 136/431 (31%), Gaps = 60/431 (13%) Query: 43 NLEKLKNNYLFPEINRRELEHIEKHPNVQLISLGTG----DTTEPIPEQITSHMSNFAHG 98 N+E L + LF + + + LG G D +P H Sbjct: 7 NIELLPPDALFG-----IKQRYGQDQRATKVDLGIGAYRDDNGKPWVLPSVKAAEKLIHN 61 Query: 99 LSTVEGYRGYGLEQGNKTLRKAIAE--TFYRDLHVKSNEVFV-----SDGAQSDISRLQL 151 S+ Y G +L A+ + ++ + V GA ++ Sbjct: 62 DSSYN--HEYLGITGLPSLTSNAAKIIFGTQSDALQEDRVISVQSLSGTGALHISAKFFS 119 Query: 152 LLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTP 211 + + + PT+ ++ G + + + N F + P Sbjct: 120 KFFPDKLVYLSKPTWANHMAIFENQGLKTATYPYWANETKSLDL-----NGFLNAIQKAP 174 Query: 212 RTDVIFFCS-PNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIP 270 + S +NPTG + +Q Q+VD + I +FD+AY F + Y + Sbjct: 175 EGSIFVLHSCAHNPTGLDPTSEQWVQIVDAIASKNHIALFDTAYQGFATGDLDKDAYAVR 234 Query: 271 GAREV------AIEVSSFSKFAGFTGVRLGW---SIIPDELLYSNGFPIINDFHRIVTTS 321 E SF+K AG G R+G ++ + + + +I+ + Sbjct: 235 LGVEKLSTVSPVFVCQSFAKNAGMYGERVGCFHLALTKQAQNKTIKPAVTSQLAKIIRSE 294 Query: 322 FNGASNIAQAGGLAC-----LSSGGLKEIRSVNNYYKENRKILMDTLVSLG----LKVYG 372 + L+ K++ ++++ + R L D LV LG Sbjct: 295 VSNPPAYGAKIVAKLLETPELTEQWHKDMVTMSSRITKMRHALRDHLVKLGTPGNWDHIV 354 Query: 373 GVNAPYLWVHFKGSKSWDVFNEILENTHIITVPGSGFGPGGEEYLRISGF----GRRDHI 428 + + + LE TH + + SG R S G +++ Sbjct: 355 NQCGMFSFTGLTPQ-----MVKRLEETHAVYLVASG---------RASIAGLNQGNVEYV 400 Query: 429 VEASKRLQNFF 439 +A + F+ Sbjct: 401 AKAIDEVVRFY 411 >4RKC-A nrPDB Length = 398 Score = 86.0 bits (211), Expect = 3e-17, Method: Composition-based stats. Identities = 55/355 (15%), Positives = 101/355 (28%), Gaps = 28/355 (7%) Query: 62 EHIEKHPNVQLISLGTGDT-TEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKA 120 E N ++LG G E + + ++ R Y G RK Sbjct: 18 EKFAADNNPDKVNLGIGIYYDESGVMPVLDCVKIAEQRIADPISPRPYLPMAGLPGHRKG 77 Query: 121 IAET-FYRDLHVKSNEV---FVSDGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDSSVII 176 E F +D V + + + G + + P Y+ Sbjct: 78 CQELLFGKDAPVLKDGLVATIATIGGSGALKVGAEFIHE------WFPQSKCYVSDPTWG 131 Query: 177 GQTGHFHEKTKKYQNVVYMPCGPNNSFFPD----LAMTPRTDVIFF--CSPNNPTGYVAS 230 F + Y F + + DV+ C +NPTG + Sbjct: 132 NHIAIFEGCDIEVGKYPYYDTATGGIKFDEMIAFFETLNKDDVLLLHPCC-HNPTGVDLT 190 Query: 231 RKQLHQLVDFAKTNGSIIIFDSAYAAFIE--DGSPRSIYEIPGAREVAIEVSSFSKFAGF 288 R+Q +++ + I D AY F E D +I + +SFSK Sbjct: 191 REQWDTVLNVIQERELIPFMDIAYQGFGEDMDSDAYAIRKAVDMGLPLFVSNSFSKNLSL 250 Query: 289 TGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGL----ACLSSGGLKE 344 G R+G + + + + S+ + + A L + E Sbjct: 251 YGERVGGLSVVCPTVDETERVFGQLNSTVRRIYSSPPSHGGRVVDIVMNDAALHEQWVGE 310 Query: 345 IRSVNNYYKENRKILMDTLVS----LGLKVYGGVNAPYLWVHFKGSKSWDVFNEI 395 + ++ + K R L L + N + + + + +E Sbjct: 311 VYAMRDRIKSMRTKLKSVLEAKISGRNFDYLTAQNGMFSFTGLTPEQVERLQSEF 365 >4W5K-A nrPDB Length = 396 Score = 85.2 bits (209), Expect = 5e-17, Method: Composition-based stats. Identities = 46/319 (14%), Positives = 91/319 (28%), Gaps = 29/319 (9%) Query: 67 HPNVQLISLGTGDTTEPIPEQ-ITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETF 125 P + ++L G + + + + G + Y G + + + Sbjct: 25 DPAKRKVNLSIGVYRDDADQPFVLECVKQATLGTNMD-----YAPVTGIASFVEEAQKLC 79 Query: 126 YRDLH--VKSNEV--FVSDGAQSDI----SRLQLLLGSNVTIAVQDPTFPAYIDSSVIIG 177 + ++ + + G + L + + I D +P + G Sbjct: 80 FGPTCAALRDGRIASCQTLGGTGALRIGGDLLNRFVANCNRIYGPDVGYPNHESIFAKAG 139 Query: 178 QTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFF-CSPNNPTGYVASRKQLHQ 236 + + + L P VI +NPTG + Q Sbjct: 140 MELTPYSYYDPATKGLNLAGMLEC-----LDKAPEGSVILVHACAHNPTGVDPTHDDWRQ 194 Query: 237 LVDFAKTNGSIIIFDSAYAAFIE---DGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRL 293 + D K I D AY F D + I SFS G G R Sbjct: 195 VCDVIKRRNHIPFVDMAYQGFATGQLDYDAFVPRHLVDMVPNLIVAQSFSANFGLYGHRC 254 Query: 294 GWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSS-----GGLKEIRSV 348 G ++ +++ ++ ++ + L KE++ + Sbjct: 255 G-ALHISTASAEEAKRLVSQLALLIRPMYSNPPLYGAWVVSSILKDPQLTALWKKELKQM 313 Query: 349 NNYYKENRKILMDTLVSLG 367 ++ E RK L+ L + G Sbjct: 314 SSRIAEVRKRLVSELKACG 332 >6EZL-A nrPDB Length = 404 Score = 85.2 bits (209), Expect = 6e-17, Method: Composition-based stats. Identities = 69/370 (18%), Positives = 124/370 (33%), Gaps = 30/370 (8%) Query: 54 PEINRRELEHIEKHPNVQLISLGTGDTT-EPIPEQITSHMSNFAHGLSTVEGY---RGYG 109 P + + P LI D P P + ++ + Y GY Sbjct: 17 PIFSASLVAKKAPEPKADLIIGAYRDAEGHPYPLNVVRKAEQRLLEMNADKEYLPMSGYA 76 Query: 110 LEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQDPTFPAY 169 ++L+ A ++ R+ V + + L +L + + + DPT+P + Sbjct: 77 PFI-EESLKIAYGDSVARENVVGIQGLSGTGSLSIGACFLARVLSRDTPVYISDPTWPNH 135 Query: 170 IDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFF-CSPNNPTGYV 228 +V+ K + Y N C + DL P ++ +NPTG Sbjct: 136 Y--AVMAAANLTDLRKYRYYDNAK--RCIDFDGLLEDLNGAPEGSIVILHACAHNPTGMD 191 Query: 229 ASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEV---SSFSKF 285 + +Q ++++ + I FDSAY + Y I +E+ S+SK Sbjct: 192 PTHEQWAKILEVFQARRLIPFFDSAYQGYATGSLDNDAYSIRLFARQGMEMLLAQSYSKN 251 Query: 286 AGFTGVRLGWSII------PDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSS 339 G R+G I L+ S I+ + T +GA L + Sbjct: 252 MGLYAERVGVCSIVTANPKKAPLIKSQLETIVR--SQYSTPPAHGARVAYLVLSDPELRA 309 Query: 340 GGLKEIRSVNNYYKENRKILMDTLVSLG----LKVYGGVNAPYLWVHFKGSKSWDVFNEI 395 G +E+R ++ E R+ L D L LG + + ++ E Sbjct: 310 GWEQELRVMSTRVLEMRQALYDGLKRLGTPGSWEHIIQQVGMFSYLGL-----TKAQCEK 364 Query: 396 LENTHIITVP 405 L + +P Sbjct: 365 LIERRVFVLP 374 >3II0-A nrPDB Length = 422 Score = 83.3 bits (204), Expect = 2e-16, Method: Composition-based stats. Identities = 60/368 (16%), Positives = 101/368 (27%), Gaps = 38/368 (10%) Query: 66 KHPNVQLISLGTG--DTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAE 123 + P+ + ++LG G T + P + + Y G R + Sbjct: 15 EDPDPRKVNLGVGAYRTDDCHPWVLPVVKKVEQKIANDNSLNHEYLPILGLAEFRSCASR 74 Query: 124 TFYRDLH--VKSNEV--FVSDGAQSDISRLQLLL--------GSNVTIAVQDPTFPAYID 171 D +K V S G + L N + V PT+ + Sbjct: 75 LALGDDSPALKEKRVGGVQSLGGTGALRIGADFLARWYNGTNNKNTPVYVSSPTWENH-- 132 Query: 172 SSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFF-CSPNNPTGYVAS 230 ++V + + F DL P ++ +NPTG + Sbjct: 133 NAVFSAAGFKDIRSYRYWDAEKRGLDLQ--GFLNDLENAPEFSIVVLHACAHNPTGIDPT 190 Query: 231 RKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVS---SFSKFAG 287 +Q Q+ K FDSAY F R + I E SFSK G Sbjct: 191 PEQWKQIASVMKHRFLFPFFDSAYQGFASGNLERDAWAIRYFVSEGFEFFCAQSFSKNFG 250 Query: 288 FTGVRLG--WSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEI 345 R+G + + + RI + N + A+ + +E Sbjct: 251 LYNERVGNLTVVGKEPESILQVLSQMEKIVRITWS--NPPAQGARIVASTLSNPELFEEW 308 Query: 346 RSVNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSWDVFN--------EILE 397 + + L + L+ W H F ++ Sbjct: 309 TGNVKTMADRILTMRSELRA-RLEALKTPGT---WNHITDQIGMFSFTGLNPKQVEYLVN 364 Query: 398 NTHIITVP 405 HI +P Sbjct: 365 EKHIYLLP 372 >1TAR-A nrPDB Length = 401 Score = 82.9 bits (203), Expect = 3e-16, Method: Composition-based stats. Identities = 57/355 (16%), Positives = 117/355 (32%), Gaps = 26/355 (7%) Query: 62 EHIEKHPNVQLISLGTGDT-TEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKA 120 E ++ N + ++LG G + + + + ++ + + Y G +A Sbjct: 20 EAFKRDTNSKKMNLGVGAYRDDNGKPYVLNCVRKAEAMIAAKKMDKEYLPIAGLADFTRA 79 Query: 121 IAET--------FYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDS 172 AE F +V + + + + LQ + + + P++ + Sbjct: 80 SAELALGENSEAFKSGRYVTVQGISGTGSLRVGANFLQRFFKFSRDVYLPKPSWGNHTPI 139 Query: 173 SVIIG-QTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASR 231 G Q + K ++ + + S P+ ++ ++ +NPTG + Sbjct: 140 FRDAGLQLQAYRYYDPKTCSLDFTGAMEDISKIPEKSI-----ILLHACAHNPTGVDPRQ 194 Query: 232 KQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEV---SSFSKFAGF 288 +Q +L K + FD AY F R + + E I+V S++K G Sbjct: 195 EQWKELASVVKKRNLLAYFDMAYQGFASGDINRDAWALRHFIEQGIDVVLSQSYAKNMGL 254 Query: 289 TGVRLG-WSII---PDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKE 344 G R G +++I +E I NGA + L L E Sbjct: 255 YGERAGAFTVICRDAEEAKRVESQLKILIRPMYSNPPMNGARIASLILNTPELRKEWLVE 314 Query: 345 IRSVNNYYKENRKILMDTLVSLG----LKVYGGVNAPYLWVHFKGSKSWDVFNEI 395 ++ + + R L+ L G + + + K + + E Sbjct: 315 VKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPEQVERLTKEF 369 >2CST-A nrPDB Length = 411 Score = 81.3 bits (199), Expect = 9e-16, Method: Composition-based stats. Identities = 58/365 (15%), Positives = 104/365 (28%), Gaps = 40/365 (10%) Query: 66 KHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGY--RGYGLEQGNKTLRKAIAE 123 + + + ++LG G + + L +G Y G R + Sbjct: 25 EDGDSRKVNLGVGAYRTDEGQPWVLPVVRKVEQLIAGDGSLNHEYLPILGLPEFRANASR 84 Query: 124 TFYRDLH--VKSNEV--FVSDGAQSDISRLQLLL--------GSNVTIAVQDPTFPAYID 171 D + V G + L + + V PT+ + Sbjct: 85 IALGDDSPAIAQKRVGSVQGLGGTGALRIGAEFLRRWYNGNNNTATPVYVSSPTWENH-- 142 Query: 172 SSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFF-CSPNNPTGYVAS 230 +SV + + + D+ P + +NPTG + Sbjct: 143 NSVFMDAGFKDIRTYRYWDAAKRGLDLQ--GLLDDMEKAPEFSIFILHACAHNPTGTDPT 200 Query: 231 RKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVS---SFSKFAG 287 + Q+ K FDSAY F + + + E+ SFSK G Sbjct: 201 PDEWKQIAAVMKRRCLFPFFDSAYQGFASGSLDKDAWAVRYFVSEGFELFCAQSFSKNFG 260 Query: 288 FTGVRLG--WSIIPDELLYSNGFPIINDFHRIVTTSF-NGASNIAQAGGLACLSSGGLKE 344 R+G + DE N +++ +IV T++ N S A+ S E Sbjct: 261 LYNERVGNLSVVGKDE---DNVQRVLSQMEKIVRTTWSNPPSQGARIVATTLTSPQLFAE 317 Query: 345 IRSVNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSWDVFN--------EIL 396 + + ++ L S + P W H F ++ Sbjct: 318 WKDNVKTMADRVLLMRSELRSR----LESLGTPGTWNHITDQIGMFSFTGLNPKQVEYMI 373 Query: 397 ENTHI 401 + HI Sbjct: 374 KEKHI 378 >5IWQ-A nrPDB Length = 434 Score = 80.9 bits (198), Expect = 1e-15, Method: Composition-based stats. Identities = 61/425 (14%), Positives = 126/425 (29%), Gaps = 54/425 (12%) Query: 42 VNLEKLKNNYLFPEINRRELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMS---NFAHG 98 + + + +I R+ E K+ + L G + + ++ Sbjct: 7 QDFDAERIGLFHEDIKRKFDELKSKN---LKLDLTRGKPSSEQLDFADELLALPGKGDFK 63 Query: 99 LSTVEGYRGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRLQL----LLG 154 + R YG G +R+ A+ V +V D + +I + + G Sbjct: 64 AADGTDVRNYGGLDGIVDIRQIWADLL----GVPVEQVLAGDASSLNIMFDVISWSYIFG 119 Query: 155 SNVTI-----------AVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSF 203 +N ++ P + + + G + +V GP+ Sbjct: 120 NNDSVQPWSKEETVKWICPVPGYDRHFSITERFG---------FEMISVPMNEDGPDMDA 170 Query: 204 FPDLAMTPRTDVIFFC-SPNNPTGYVASRKQLHQLVDF-AKTNGSIIIFDSAYAAFIEDG 261 +L P+ ++ +NPTG+ + +L +++D+AYA Sbjct: 171 VEELVKNPQVKGMWVVPVFSNPTGFTVTEDVAKRLSAMETAAPDFRVVWDNAYAVHTLTD 230 Query: 262 SPRSIYEIPGARE------VAIEVSSFSKFAGFTGVRLGWSIIPDE-LLYSNGFPIINDF 314 + +I G E +S SK G + + + E + G I Sbjct: 231 EFPEVIDIVGLGEAAGNPNRFWAFTSTSKIT-LAGAGVSFFLTSAENRKWYTGHAGIRGI 289 Query: 315 HRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILMDTLVSLGL-KVYGG 373 A A G+ + + N E IL L G+ + Sbjct: 290 GPNKVNQLAHARYFGDAEGVRAVMRKHAASLAPKFNKVLE---ILDSRLAEYGVAQWTVP 346 Query: 374 VNAPYLWVHFKGSKSWDVFNEILENTHIITV-PGSGF---GPGGEEYLRISGFGRR-DHI 428 ++ + + V E+ + I GS + + LR++ + + Sbjct: 347 AGGYFISLDVVPGTASRVA-ELAKEAGIALTGAGSSYPLRQDPENKNLRLAPSLPPVEEL 405 Query: 429 VEASK 433 A Sbjct: 406 EVAMD 410 >4H51-A nrPDB Length = 420 Score = 78.6 bits (192), Expect = 5e-15, Method: Composition-based stats. Identities = 61/352 (17%), Positives = 110/352 (31%), Gaps = 29/352 (8%) Query: 29 MKKLGGSTKLVRNVNLEKLKNNYLFPEINRRELEHIEKHPNVQLISLGTG----DTTEPI 84 M T R ++ + +F ++ +R K P +L G + P Sbjct: 9 MSTQAAMTTAERWQKIQAQAPDVIF-DLAKRAAA--AKGPKA---NLVIGAYRDEQGRPY 62 Query: 85 PEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFV-----S 139 P ++ ++ Y G + + Y + N V V + Sbjct: 63 PLRVVRKAEQLLLDMNLDYE---YLPISGYQPFIDEAVKIIYGNTVELENLVAVQTLSGT 119 Query: 140 DGAQSDISRLQLLLGSNVT-IAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCG 198 L + + T I + DPT+P + G + T Y + + Sbjct: 120 GAVSLGAKLLTRVFDAETTPIYLSDPTWPNHYGVVKAAGWK---NICTYAYYDPKTVSLN 176 Query: 199 PNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFI 258 LA + I +NPTG S++Q +++ + FDSAY + Sbjct: 177 FEGMKKDILAAPDGSVFILHQCAHNPTGVDPSQEQWNEIASLMLAKHHQVFFDSAYQGYA 236 Query: 259 EDGSPRSIYEIPGAREVAIEV---SSFSKFAGFTGVRLGW--SIIPDELLYSNGFPIIND 313 Y IEV SFSK G R G ++ D+ ++ +++ Sbjct: 237 SGSLDTDAYAARLFARRGIEVLLAQSFSKNMGLYSERAGTLSLLLKDKTKRADVKSVMDS 296 Query: 314 FHR--IVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILMDTL 363 R +GA L E+ ++ + R+ + D L Sbjct: 297 LIREEYTCPPAHGARLAHLILSNNELRKEWEAELSAMAERIRTMRRTVYDEL 348 >3MEB-A nrPDB Length = 448 Score = 78.6 bits (192), Expect = 5e-15, Method: Composition-based stats. Identities = 56/371 (15%), Positives = 121/371 (32%), Gaps = 27/371 (7%) Query: 44 LEKLKNNYLFPEINRRELEHIEKHPNVQLISLGTGDT-TEPIPEQITSHMSNFAHGLSTV 102 + +N L + + +P ++LG G E I + +S+ Sbjct: 25 FSGFPASPPDAILNLTVLYNADTNPKK--VNLGVGAYRDESGKPWILPAVKEAEAIISSD 82 Query: 103 --EGYRGYGLEQGNKTLRKAIAETF--------YRDLHVKSNEVFVSDGAQSDISRLQLL 152 + + Y G +A A+ ++ + S + G+ L Sbjct: 83 LSKYNKEYPPVAGFPLFLEA-AQFLMFGKDSKAAQEGRIASCQSLSGTGSLHIGFEFLHL 141 Query: 153 LGSNVTIAVQDPTFP-AYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTP 211 + T+P Y + + +++ + + +N+ + Sbjct: 142 WMPKAEFYMPSTTWPNHYGIYDKVFNKLKVPYKEYTYLRKDGELEIDFSNTKKDIQSAPE 201 Query: 212 RTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPG 271 ++ +F +NP+G + Q +L+ K I FDSAY F + + Sbjct: 202 KSIFLFHACAHNPSGIDFTEAQWKELLPIMKEKKHIAFFDSAYQGFATGSFEADAFAVRM 261 Query: 272 AREVAIEV---SSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNI 328 + +EV SFSK G G R+G ++++ + + +G + Sbjct: 262 FVDAGVEVLVAQSFSKNFGLYGERIGCL----HVVHAGVEGSVEKNKALSAAMVSGMT-- 315 Query: 329 AQAGGLACLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLKVYGGVN---APYLWVHFKG 385 Q +S+ I V + K ++ D + + +++ + A G Sbjct: 316 LQIRKTWSMSAIHGAYIVQVIVHDKRLLQMFYDNVKEMSARIHRMRSLLHASLAKRKTPG 375 Query: 386 SKSWDVFNEIL 396 S ++ IL Sbjct: 376 PGSKGTWDHIL 386 >4WB0-B nrPDB Length = 414 Score = 77.1 bits (188), Expect = 2e-14, Method: Composition-based stats. Identities = 58/366 (15%), Positives = 115/366 (31%), Gaps = 32/366 (8%) Query: 60 ELEHIEKHPNVQLISLGTG----DTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNK 115 EL +L G + P P ++ ++ Y G + Sbjct: 28 ELAKRAAAAKGPKANLVIGAYRDEQGLPYPLRVVRKAEQLLLDMNLNYE---YLPISGYQ 84 Query: 116 TL-RKAIAETFYRDLHVKSNEVFVSDGAQSDISR----LQLLLGSNVT-IAVQDPTFPAY 169 +A+ T+ + +++ + +S L + + T I + DPT+P + Sbjct: 85 PFIDEAVKMTYGDTVELENLVAVQTLSGTGALSLGAKLLTHVFDAEKTPIYLADPTWPNH 144 Query: 170 IDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVA 229 G +T Y + + LA + + +NPTG Sbjct: 145 YSIVKAAGWKDI---RTYAYYDHKTLGLDFEGMKKDILAAPDGSVFLLHQCAHNPTGVDP 201 Query: 230 SRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEV---SSFSKFA 286 S++Q +++ + FDSAY + Y IEV SFSK Sbjct: 202 SQEQWNEIASLMLAKHHQVFFDSAYQGYASGSLDTDAYAARLFARRGIEVLLAQSFSKNM 261 Query: 287 GFTGVRLGW--SIIPDELLYSNGFPIINDFHR--IVTTSFNGASNIAQAGGLACLSSGGL 342 G R G ++ D+ ++ +++ R +GA L Sbjct: 262 GLYSERAGTLSLLLKDKTKRADVKSVMDSLIRAEYTCPPAHGARLAHLILSNNELRKEWE 321 Query: 343 KEIRSVNNYYKENRKILMDTLVSL----GLKVYGGVNAPYLWVHFKGSKSWDVFNEILEN 398 E+ ++ + R+ + D L+ L + + ++ + E +N Sbjct: 322 AELSAMAERIRTMRRTVYDELLRLQTPGRWEHVINQIGMFSFLGLSKEQ-----CEYCQN 376 Query: 399 THIITV 404 +I Sbjct: 377 HNIFIT 382 >5TON-A nrPDB Length = 414 Score = 76.3 bits (186), Expect = 3e-14, Method: Composition-based stats. Identities = 61/367 (16%), Positives = 105/367 (28%), Gaps = 36/367 (9%) Query: 66 KHPNVQLISLGTG--DTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAE 123 + P+ + ++LG G T + P + + Y G R + Sbjct: 28 EDPDPRKVNLGVGAYRTDDCQPWVLPVVRKVEQRIANNSSLNHEYLPILGLAEFRTCASR 87 Query: 124 TFYRDLHVKSNEVFV----SDGAQSDISRLQLLL-------GSNVT-IAVQDPTFPAYID 171 D E V S G + L + T + V PT+ Sbjct: 88 LALGDDSPALQEKRVGGVQSLGGTGALRIGAEFLARWYNGTNNKDTPVYVSSPTWENLNG 147 Query: 172 SSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFF-CSPNNPTGYVAS 230 G F + F DL P + +NPTG + Sbjct: 148 VFTTAG----FKDIRSYRYWDTEKRGLDLQGFLSDLENAPEFSIFVLHACAHNPTGTDPT 203 Query: 231 RKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVS---SFSKFAG 287 +Q Q+ K FDSAY F + + I E+ SFSK G Sbjct: 204 PEQWKQIASVMKRRFLFPFFDSAYQGFASGNLEKDAWAIRYFVSEGFELFCAQSFSKNFG 263 Query: 288 FTGVRLG-WSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIR 346 R+G +++ E + +++ +IV +++ AQ + + + Sbjct: 264 LYNERVGNLTVVAKE--PDSILRVLSQMQKIVRVTWSNPP--AQGARIVARTLSDPELFH 319 Query: 347 SVNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSWDVFN--------EILEN 398 K ++ L + + P W H F ++ Sbjct: 320 EWTGNVKTMADRILSMRSELRAR-LEALKTPGTWNHITDQIGMFSFTGLNPKQVEYLINQ 378 Query: 399 THIITVP 405 HI +P Sbjct: 379 KHIYLLP 385 >4EFF-A nrPDB Length = 420 Score = 75.2 bits (183), Expect = 5e-14, Method: Composition-based stats. Identities = 54/314 (17%), Positives = 107/314 (34%), Gaps = 20/314 (6%) Query: 71 QLISLGTG-DTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYRDL 129 ++LG G T E + + + RGY G ++ + D Sbjct: 50 TKVNLGVGVYTNEDGKIPLLRAVRDAEKARVEAGLPRGYLPIDGIAAYDASVQKLLLGDD 109 Query: 130 H--VKSNEVFVS--DGAQSDI---SRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHF 182 + + V + G + + L +A+ DP++ + + G Sbjct: 110 SPLIAAGRVVTAQALGGTGALKIGADFLRTLNPKAKVAISDPSWENHRALFDMAGFEVVA 169 Query: 183 HEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAK 242 + N V + P T V+ +NPTG + Q Q+V+ K Sbjct: 170 YPYYDAKTNGVNFDGMLAALNGYE----PGTIVVLHACCHNPTGVDLNDAQWAQVVEVVK 225 Query: 243 TNGSIIIFDSAYAAFIE--DGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPD 300 + D AY F E + ++ A SSFSK G R+G I Sbjct: 226 ARRLVPFLDIAYQGFGESIEADAAAVRLFAAANLNVFVSSSFSKSFSLYGERVGALSIIT 285 Query: 301 ELLYSNGFPIINDFHRIVTTSFNGASN-----IAQAGGLACLSSGGLKEIRSVNNYYKEN 355 + +++ R++ T+++ +A L + ++E+ + + + Sbjct: 286 DSK-DEAARVLSQLKRVIRTNYSNPPTHGGAIVAAVLASPELRASWVQELGEMRDRIRAM 344 Query: 356 RKILMDTLVSLGLK 369 R L++ L + G++ Sbjct: 345 RNGLVERLKAAGIE 358 >2X8U-A nrPDB Length = 412 Score = 67.5 bits (163), Expect = 1e-11, Method: Composition-based stats. Identities = 45/288 (15%), Positives = 84/288 (29%), Gaps = 30/288 (10%) Query: 84 IPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQ 143 + + G G + G KA + + + + S G Q Sbjct: 59 FDPDVIAAGKQALDEFG--SGTTGSRVLNGTYQGHKACEDALKEFYGTE-HAIVFSTGYQ 115 Query: 144 SDISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQT-GHFHEKTKKYQNVVYMPCGPNNS 202 +++ + L G I + + + D + F + + + Sbjct: 116 ANLGMISTLAGKGDYIILDADSHASIYDGCWLGDAEIVRFRHNSVEDLDKRLGRLPAEAG 175 Query: 203 FFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGS 262 L + G +A L ++V +K +G++I+ D A+ Sbjct: 176 KLVVL---EGVYSMM--------GDIAP---LQEMVAVSKKHGAMILVDEAHGMGFFGEH 221 Query: 263 PRSIYEIPG-AREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTS 321 R ++E G +V V +FSK G G G+ + P + Sbjct: 222 GRGVFEEAGVEADVDFVVGTFSKSVGTVG---GFCVSN--------HPKFEVLRLVCRPY 270 Query: 322 FNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLK 369 AS A S L + +N + L L +G K Sbjct: 271 VFTASLPPSVVATAATSIRKLMHAGDKRAHLWKNSRRLHQGLRDMGYK 318 >1M6S-A nrPDB Length = 347 Score = 66.3 bits (160), Expect = 3e-11, Method: Composition-based stats. Identities = 66/383 (17%), Positives = 123/383 (32%), Gaps = 47/383 (12%) Query: 69 NVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYRD 128 +I L + T+P E++ M+ G YG + L + AETF ++ Sbjct: 2 PHMMIDLRSDTVTKPT-EEMRKAMAQAEVGDDV------YGEDPTINELERLAAETFGKE 54 Query: 129 LHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQDPTFPAYID---SSVIIGQTGHFHEK 185 +FV G + + + ++ + + + +V+ G H Sbjct: 55 AA-----LFVPSGTMGNQVSIMAHTQRGDEVILEADSHIFWYEVGAMAVLSGVMPH---- 105 Query: 186 TKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTG-YVASRKQLHQLVDFAKTN 244 +N P + P PRT +I + +N +G V + + ++ AK + Sbjct: 106 PVPGKNGAMDPDDVRKAIRPRNIHFPRTSLIAIENTHNRSGGRVVPLENIKEICTIAKEH 165 Query: 245 GSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLY 304 G + D A S + E G + + SK +G ++ D Sbjct: 166 GINVHIDGARIFNASIASGVPVKEYAGYADSVMFC--LSKGLCAP---VGSVVVGDR--- 217 Query: 305 SNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILMDTLV 364 + +++ QAG LA L ++ EN + L L Sbjct: 218 -DFIERARKARKMLGGGMR------QAGVLAAAGIIALTKMVDRLKEDHENARFLALKLK 270 Query: 365 SLGLKVYGGVNAPYLWVHFKGSKSWDV---FNEILENTHIITVPGSGFGPGGEEYLRISG 421 +G V + V + F E L N+ ++ S + +R+ Sbjct: 271 EIGYSV-NPEDVKTNMVILRTDNLKVNAHGFIEALRNSGVLANAVS------DTEIRLVT 323 Query: 422 FG--RRDHIVEASKRLQNFFNTR 442 R+ I EA + F Sbjct: 324 HKDVSRNDIEEALNIFEKLFRKF 346 >4LW2-A nrPDB Length = 404 Score = 64.8 bits (156), Expect = 7e-11, Method: Composition-based stats. Identities = 69/388 (17%), Positives = 120/388 (30%), Gaps = 63/388 (16%) Query: 85 PEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFV-SDGAQ 143 PE + F + + Q +A E + L+ ++ V + G Sbjct: 35 PEAVVEATQQFYSLSAGNVHRSQFAEAQRLTARYEAAREKVAQLLNAPDDKTIVWTRGTT 94 Query: 144 SDISRLQLL-----LGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCG 198 I+ + L I V + + VV +P Sbjct: 95 ESINMVAQCYARPRLQPGDEIIV--------SVAEHHANLVPWLMVAQQTGAKVVKLPLN 146 Query: 199 ----PNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAY 254 P+ P+L +TPR+ ++ +N TG L + + FA + G +++ D A Sbjct: 147 AQRLPDVDLLPEL-ITPRSRILALGQMSNVTGGCPD---LARAITFAHSAGMVVMVDGA- 201 Query: 255 AAFIEDGSPRSIYEIPGAREVAIEVSSFS--KFAGFTGVRLGWSIIPDELLYSNGFPIIN 312 G+ ++ I+ +FS K G TG +G ELL + P + Sbjct: 202 -----QGAVHFPADVQQLD---IDFYAFSGHKLYGPTG--IGVLYGKSELLEA-MSPWLG 250 Query: 313 DFHRIVTTSFNGASNIAQ--------------AGGLACLSSGGLKEIRSVNNYYKENRKI 358 + SF+G + + G A L +I ++ + + Sbjct: 251 GGKMVHEVSFDGFTTQSAPWKLEAGTPNVAGVIGLSAALEWLADYDINQAESWSRSLATL 310 Query: 359 LMDTLVS-LGLKVYGGVNAPYLWVHFKGSKSWDVFNEILENTHIITVPGSGF------GP 411 D L G + + ++ L F G D+ +L I G Sbjct: 311 AEDALAKRPGFRSFRCQDSSLLAFDFAGVHHSDMVT-LLAEYGIALRAGQHCAQPLLAEL 369 Query: 412 GGEEYLRISGFG-----RRDHIVEASKR 434 G LR S D +V A R Sbjct: 370 GVTGTLRASFAPYNTKSDVDALVNAVDR 397 >5C6U-A nrPDB Length = 435 Score = 64.4 bits (155), Expect = 1e-10, Method: Composition-based stats. Identities = 56/432 (12%), Positives = 119/432 (27%), Gaps = 64/432 (14%) Query: 44 LEKLKNNYLFPEINRRELEHIEKHPNVQL-ISLGTGDTTEPIPEQITSHMSNFAHGLSTV 102 + L L ++ R + ++L + L G + + +S Sbjct: 2 FDSLSPQEL-AALHARHQQDYAALQGMKLALDLTRGKPSAEQLDLSNQLLSLPGDDYRDP 60 Query: 103 EGY--RGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQ----SDISRLQLLLG-- 154 EG R YG + G LR AE + + + + DI +L G Sbjct: 61 EGTDTRNYGGQHGLPGLRAIFAELL----GIAVPNLIAGNNSSLELMHDIVAFSMLYGGV 116 Query: 155 ----------SNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFF 204 + P + + + +G + + + GP+ Sbjct: 117 DSPRPWIQEQDGIKFLCPVPGYDRHFAITETMGI---------EMIPIPMLQDGPDVDLI 167 Query: 205 PDL-AMTPRTDVIF-FCSPNNPTGYVASRKQLHQLVD-FAKTNGSIIIFDSAYAAFIEDG 261 +L A+ P ++ NP+G S + + +LV + +D+AYA Sbjct: 168 EELVAVDPAIKGMWTVPVFGNPSGVTYSWETVRRLVQMRTAAPDFRLFWDNAYAVHTLTL 227 Query: 262 SPRSIYEIPGAR------EVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFH 315 ++ G +S SK + I + Sbjct: 228 DFPRQVDVLGLAAKAGNPNRPYVFASTSKIT---------FAGGGVSFFGGSLGNIAWYL 278 Query: 316 RIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNY------YKENRKILMDTLVSLGL- 368 + G + Q L + + + + ++L L + Sbjct: 279 QYAGKKSIGPDKVNQLRHLRFFGDADGVRLHMLRHQQILAPKFALVAEVLDQRLSESKIA 338 Query: 369 KVYGGVNAPYLWVHFKGSKSWDVFNEILENTHIITV-PGSGF---GPGGEEYLRIS-GFG 423 ++ + + + ++ I G+ F ++ +RI+ F Sbjct: 339 SWTEPKGGYFISLDVLPGTARRTVA-LAKDVGIAVTEAGASFPYRKDPDDKNIRIAPSFP 397 Query: 424 RRDHIVEASKRL 435 + A L Sbjct: 398 SVPDLRNAVDGL 409 >3K7Y-A nrPDB Length = 405 Score = 63.6 bits (153), Expect = 2e-10, Method: Composition-based stats. Identities = 43/237 (18%), Positives = 78/237 (32%), Gaps = 20/237 (8%) Query: 71 QLISLGTG---DTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYR 127 + I+L G + + I + N ++ + Y L G + + Sbjct: 30 EKINLSIGVCCNDDGDL--HIFDSVLNADKLVTENYKEKPYLLGNGTEDFSTLTQNLIFG 87 Query: 128 DL--HVKSNEV--FVSDGAQSDISRLQLLLG--SNVTIAVQDPTFPAYIDSSVIIGQTGH 181 + +++ ++ G I L L + T+ V +P + +++ G Sbjct: 88 NNSKYIEDKKICTIQCIGGTGAIFVLLEFLKMLNVETLYVTNPPYINHVNMIESRG---- 143 Query: 182 FHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFF-CSPNNPTGYVASRKQLHQLVDF 240 F+ K + + + + F DL P + S NP K ++++ Sbjct: 144 FNLKYINFFDYNLIDINYD-LFLNDLRNIPNGSSVILQISCYNPCSVNIEEKYFDEIIEI 202 Query: 241 AKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAI---EVSSFSKFAGFTGVRLG 294 +IIFD AY F + I E I SFSK G R G Sbjct: 203 VLHKKHVIIFDIAYQGFGHTNLEEDVLLIRKFEEKNIAFSVCQSFSKNMSLYGERAG 259 >3MKJ-A nrPDB Length = 398 Score = 60.1 bits (144), Expect = 2e-09, Method: Composition-based stats. Identities = 46/280 (16%), Positives = 81/280 (28%), Gaps = 35/280 (12%) Query: 80 TTEPIPEQITSHMSNFAHGLSTVEGYRGYGL--EQGNKTLRKAIAETFYRDLHVKSNEVF 137 + A + E Y L K +A + + Sbjct: 30 PIFQTSTFVFDSAEQGAARFALEESGYIYTRLGNPTTDALEKKLAVLERGEAGLA----- 84 Query: 138 VSDGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPC 197 + G + + L L I +S I G T F + + Sbjct: 85 TASGISAITTTLLTLCQQGDHIVS----------ASAIYGCTHAFLSHSMPKFGINVSFV 134 Query: 198 GPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAF 257 AM P T V++ +P NPT S + + A G++++ D+ + + Sbjct: 135 DAAKPEEIRAAMRPETKVVYIETPANPT---LSLVDIETVAGIAHQQGALLVVDNTFMS- 190 Query: 258 IEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRL-GWSIIPDELLYSNGFPIINDFHR 316 + P I V S +K+ G + G + E + F + D Sbjct: 191 -------PYCQQPLQLGADIVVHSVTKYINGHGDVIGGIIVGKQEFIDQARFVGLKDITG 243 Query: 317 IVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENR 356 + FN L + + G++ R N K R Sbjct: 244 GCMSPFN------AWLTLRGVKTLGIRMERHCENALKIAR 277 >6CJB-A nrPDB Length = 391 Score = 58.6 bits (140), Expect = 5e-09, Method: Composition-based stats. Identities = 35/213 (16%), Positives = 73/213 (34%), Gaps = 30/213 (14%) Query: 79 DTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKA----IAETFYRDLHVKSN 134 + + +T + + + GY + RKA IA Sbjct: 24 EPCKSTGAVMTPIYATSTYKQIAPGEHLGYEYSRTQNPTRKAYEDCIASLESGQKGFA-- 81 Query: 135 EVFVSDGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVY 194 + G + I+ + LLGS + D + G F + + N+ + Sbjct: 82 ---FASG-MAAINTVIDLLGSGDHVVAMDDLY---------GGTFRLFDKVKTRTSNLSF 128 Query: 195 MPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAY 254 + + A+TP+T +++ +P+NP + L ++ AK I + D+ + Sbjct: 129 SFIDMSVPENIEAAITPKTKLLWLETPSNP---MLKLANLRKIAAIAKKYNLITVADNTF 185 Query: 255 AAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAG 287 A +P + + I + S +K+ Sbjct: 186 A------TPWIQRPLELGFD--IVLHSATKYLN 210 >3VK2-A nrPDB Length = 398 Score = 57.1 bits (136), Expect = 2e-08, Method: Composition-based stats. Identities = 41/227 (18%), Positives = 74/227 (32%), Gaps = 33/227 (14%) Query: 140 DGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGP 199 G + S L LL + + + + G T F V Sbjct: 88 SGMGAITSTLWTLLRPGDEVLLGN----------TLYGHTFAFLHHGIGEFGVKLRHVDM 137 Query: 200 NNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIE 259 + + AMTP T VI+F SP NP + + A+ +G+ ++ D+ Y Sbjct: 138 ADLQALEAAMTPATRVIYFESPANP---NMHMADIAGVAKIARKHGATVVVDNTY----- 189 Query: 260 DGSPRSIYEIPGAREVAIEVSSFSKFAGFTG-VRLGWSIIPDELLYSNGFPIINDFHRIV 318 + P + V S +K+ G + G + L+ + D V Sbjct: 190 ---CTPYLQRPLELGADLVVHSATKYLSGHGDITAGIVVGSQALVDRIRLQGLKDMTGAV 246 Query: 319 TTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILMDTLVS 365 + + A L G+K + + + N ++L + L Sbjct: 247 LSPHD-----------AALLMRGIKTLNLRMDRHCANAQVLAEFLAR 282 >3QI6-A nrPDB Length = 392 Score = 56.7 bits (135), Expect = 2e-08, Method: Composition-based stats. Identities = 39/275 (14%), Positives = 90/275 (32%), Gaps = 32/275 (11%) Query: 138 VSDGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPC 197 S G + L+ +L + + D + G T +K NV Y P Sbjct: 87 FSSGMAAADCALRAMLRPGDHVVIPDDAY----------GGTFRLIDKVFTGWNVEYTPV 136 Query: 198 GPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAF 257 + A+ P T +I+ +P NP + S + + + + ++ D+ +A+ Sbjct: 137 ALADLDAVRAAIRPTTRLIWVETPTNP---LLSIADIAGIAQLGADSSAKVLVDNTFAS- 192 Query: 258 IEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRI 317 + P + + + S +K+ G +G +++ ++ F + + Sbjct: 193 -------PALQQPLSLGADVVLHSTTKYIGGHSDVVGGALVTNDEELDQSFAFLQNGAGA 245 Query: 318 VTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKEN---RKILMDTLV-----SLGLK 369 V F+ + L + +V + E+ +L L ++ + Sbjct: 246 VPGPFDAYLTMRGLKTLVLRMQRHSENAAAVAEFLAEHPAISTVLYPGLPSHPGHAVAAR 305 Query: 370 VYGGVNAPYLWVHFKGSKSWDVFNEILENTHIITV 404 G V + ++ T+I + Sbjct: 306 QMRGFGGM---VSVRMRAGRTAAEQLCAKTNIFIL 337 >2C81-A nrPDB Length = 418 Score = 54.7 bits (130), Expect = 8e-08, Method: Composition-based stats. Identities = 56/324 (17%), Positives = 104/324 (32%), Gaps = 61/324 (18%) Query: 109 GLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRLQLL-LGSNVTIAVQDPTFP 167 G G +++ + A+ F V V + G+ + + L+ L +G + V T+ Sbjct: 35 GYWTGEESMERKFAKAFADFNGV-PYCVPTTSGSTALMLALEALGIGEGDEVIVPSLTWI 93 Query: 168 AYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGY 227 A + + + F + + + A+T +T I P Sbjct: 94 ATATAVLNVNALPVFVDVEADTYCI--------DPQLIKSAITDKTKAII------PVHL 139 Query: 228 VASRKQLHQLVDFAKTNGSIIIFD--SAYAAFIEDGSPRSIYEIPGAREVAIEVSSFS-- 283 S + ++ + A+ + +I D ++ + + +I + + +FS Sbjct: 140 FGSMANMDEINEIAQEHNLFVIEDCAQSHGSVWNNQRAGTIGD----------IGAFSCQ 189 Query: 284 --KFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQA-------GGL 334 K T G + + L+ + D S Q G Sbjct: 190 QGKV--LTAGEGGIIVTKNPRLFELIQQLRADSRVYCDDSSELMHGDMQLVKKGDIQGSN 247 Query: 335 ACLSS-------GGLKEIRSVNNYYKENRKILMDTLVSL-GLKVYGG-----VNAPYLW- 380 CLS L+E+ N ++N L D L + G+KV Y + Sbjct: 248 YCLSEFQSAILLDQLQELDDKNAIREKNAMFLNDALSKIDGIKVMKRPPQVSRQTYYGYV 307 Query: 381 -----VHFKGSKSWDVFNEILENT 399 V F G + D F EIL Sbjct: 308 FRFDPVKFGGLNA-DQFCEILREK 330 >4W91-A nrPDB Length = 422 Score = 54.7 bits (130), Expect = 8e-08, Method: Composition-based stats. Identities = 56/433 (12%), Positives = 126/433 (29%), Gaps = 62/433 (14%) Query: 45 EKLKNNYLFPEINRRELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEG 104 L Y I R + L+ L G + + I + +A+ + V Sbjct: 13 NPLTMAYDVEAIRRDFPILSRQVHGKTLVYLDNGASAQKPQSVIDAVTHAYANEYANVHR 72 Query: 105 YRGY---GLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRL-----QLLLGSN 156 + + R+ + +E+ + A I+ + +G Sbjct: 73 GLHFLSNAATDAYEKSRETVRRFLNAG---SVDEIVFTKNATEAINTVAYGYGMPFIGEG 129 Query: 157 VTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPD---LAMTPRT 213 I + + ++ +V+ P N F + ++ RT Sbjct: 130 DEILL--------SIMEHHSNIVPWHFIRERQGAKLVFTPVDDNGVFHIEEFEKRLSERT 181 Query: 214 DVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAR 273 ++ +N G V + ++V+ A G ++ D G+ ++ Sbjct: 182 KLVAITHMSNTLGTVVP---IKKIVELAHARGIPVLVD------GSQGAVHLPVDVQDL- 231 Query: 274 EVAIEVSSFSKFAGFTGVRLGWS-----------IIPDELLYSNGFPIINDFHRIVTTSF 322 V + K G +G+ + + E++ + H Sbjct: 232 GCDWYVFTGHKVYGPSGIGVLYGRAQMLEKMRPFQGGGEMIEEVTEENVTYNHPPHRFEA 291 Query: 323 NGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILMDTLVSL-GLKVYG--GVNAPYL 379 + G A L ++ + + R + L + L+++G + Sbjct: 292 GTPPIVQAIGLGAALEYMEKIGRHAILAHEADLRDYAHERLGRINSLRIFGNAPDKGAII 351 Query: 380 WVHFKGSKSWDVFNEILENTHIITVPGS--------GFGPGGEEYLRISGF-----GRRD 426 +G + DV + +++ + G+ FG R S D Sbjct: 352 SFALEGIHAHDV-SMVIDRAGVAVRAGTHCAQPLLKRFGV--TSTCRASFALYNTRAEVD 408 Query: 427 HIVEASKRLQNFF 439 + EA ++ + FF Sbjct: 409 ALAEALEKARKFF 421 >3TQX-A nrPDB Length = 399 Score = 54.0 bits (128), Expect = 1e-07, Method: Composition-based stats. Identities = 50/337 (14%), Positives = 99/337 (29%), Gaps = 42/337 (12%) Query: 115 KTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDSSV 174 K L K I+E + + S ++ + LLG I + + ID Sbjct: 91 KELEKDISEFLG-----TDDTILYSSCFDANGGLFETLLGPEDAIISDELNHASIIDGIR 145 Query: 175 IIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRT---DVIFFCSPNNPTGYVASR 231 + + ++ + L T D I Sbjct: 146 LCKAQRYRYKNNAMGDLEAKLKEADEKGARFKLIATDGVFSMDGII-------------- 191 Query: 232 KQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVA-IEVSSFSKFAGFTG 290 L + D A ++++ D ++A + R E G + I + K G G Sbjct: 192 ADLKSICDLADKYNALVMVDDSHAVGFIGENGRGTPEYCGVADRVDILTGTLGKALG--G 249 Query: 291 VRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAG--GLACLSSGGLKEIRSV 348 G++ E++ + + R S A I L L + G + + Sbjct: 250 ASGGYTSGHKEII-----EWLRNRSRPYLFSNTVAPVIVATSLKVLELLKTEGPQ----L 300 Query: 349 NNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSWDVFNEILENTHIITVPGSG 408 +EN + + LG ++ G + + + ++ + +L+ I V G Sbjct: 301 RKQLQENSRYFRAGMEKLGFQLVPGNHPIIPVMLGDAQLATNMADHLLQEG--IYVVGFS 358 Query: 409 FGPGGEEYLRI----SGFGRRDHIVEASKRLQNFFNT 441 + RI S + + A + Sbjct: 359 YPVVPMGKARIRVQMSAVHTQQQLDRAIEAFGQVGKK 395 >6ONN-A nrPDB Length = 402 Score = 53.6 bits (127), Expect = 2e-07, Method: Composition-based stats. Identities = 48/321 (14%), Positives = 95/321 (29%), Gaps = 43/321 (13%) Query: 125 FYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHE 184 F ++ S G ++++ L L G T+ + ID + + + Sbjct: 104 FAGGFVDNPRALYFSTGYMANLATLTALAGRGTTLFSDSLNHASLIDGARLSRADIQIYP 163 Query: 185 KTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQ----LHQLVDF 240 + +I + V S L +L++ Sbjct: 164 HADAEALGAMLEAS-----------DAAVKLIV-------SDTVFSMDGDIAPLARLLEL 205 Query: 241 AKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGARE-VAIEVSSFSKFAGFTGVRLGWSIIP 299 A+ +G+ ++ D A+ + R R I V + K AG +G + + Sbjct: 206 AEHHGAWLVVDDAHGFGVLGPQGRGAVAEAALRSPHLIVVGTLGKAAGVSG---AFVVAH 262 Query: 300 DELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKIL 359 + ++ ++ + T+ + S A A L G E + + + Sbjct: 263 ETVI----EWLVQRARPYIFTTASVPS--AAHAVSASLRIIGGDEGEHRRAHLRSLIALT 316 Query: 360 MDTLVSLGLKVYGGVNAPYLWVHFKGSKSWDVFNEILENTHI---ITVPGSGFGPGGEEY 416 D L S A + + DV L+ ++ P + P G Sbjct: 317 RDMLKSTPWLPVDSHTAVQPLIIGSNEATLDVAAS-LDRANLWVPAIRPPTV--PEGTSR 373 Query: 417 LRISGF-----GRRDHIVEAS 432 LRIS + + A Sbjct: 374 LRISLSAAHSHNDLEQLEHAL 394 >4PIW-A nrPDB Length = 396 Score = 53.6 bits (127), Expect = 2e-07, Method: Composition-based stats. Identities = 49/331 (14%), Positives = 98/331 (29%), Gaps = 49/331 (14%) Query: 98 GLSTVEGYRGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLG--S 155 L ++ G G G+ + + + S +V ++ + + LLL Sbjct: 33 ELDYMQSAMGSGKLCGDGGFTRRCQQWLEQRFG--SAKVLLTPSCTASLEMAALLLDIQP 90 Query: 156 NVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDV 215 + + TF + ++ V+ G F + N+ + + A+T +T V Sbjct: 91 GDEVIMPSYTFVSTANAFVLRGAKIVFVDVRPDTMNI--------DETLIEAAITDKTRV 142 Query: 216 IFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREV 275 I P Y ++ ++ AK + ++ D+A + R++ I Sbjct: 143 IV------PVHYAGVACEMDTIMALAKKHNLFVVEDAA-QGVMSTYKGRALGTIGH---- 191 Query: 276 AIEVSSF--SKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRI---------------- 317 I SF +K G G ++I D+ L I Sbjct: 192 -IGCFSFHETKNY-TAGGEGGATLINDKALIERAEIIREKGTNRSQFFRGQVDKYTWRDI 249 Query: 318 -VTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILMDT---LVSLGLKVYGG 373 + + L + + NYY + L S+ Sbjct: 250 GSSYLMSDLQAAYLWAQLEAADRINQQRLALWQNYYDALAPLAKAGRIELPSIPDGCV-- 307 Query: 374 VNAPYLWVHFKGSKSWDVFNEILENTHIITV 404 NA ++ + L+ I+ V Sbjct: 308 QNAHMFYIKLRDIDDRSALINFLKEAEIMAV 338 >4BMK-A nrPDB Length = 442 Score = 53.6 bits (127), Expect = 2e-07, Method: Composition-based stats. Identities = 38/245 (15%), Positives = 74/245 (30%), Gaps = 27/245 (11%) Query: 127 RDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQT-GHFHEK 185 RD + + + S G +++ + L G + + + + D F Sbjct: 141 RDFYGTTGAIVFSTGYMANLGIISTLAGKGEYVILDADSHASIYDGCQQGNAEIVRFRHN 200 Query: 186 TKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNG 245 + + + + L G +A L ++V AK +G Sbjct: 201 SVEDLDKRLGRLPKEPAKLVVLEGVYSM-----------LGDIAP---LKEMVAVAKKHG 246 Query: 246 SIIIFDSAYAAFIEDGSPRSIYEIPGAR-EVAIEVSSFSKFAGFTGVRLGWSIIPDELLY 304 ++++ D A++ + R +YE G ++ V +FS G G G+ + Sbjct: 247 AMVLVDEAHSMGFFGPNGRGVYEAQGLEGQIDFVVGTFSASVGTVG---GFVVSN----- 298 Query: 305 SNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILMDTLV 364 P AS A S L N + L L Sbjct: 299 ---HPKFEAVRLACRPYIFTASLPPSVVATATTSIRKLMTAHEKRERLWSNARALHGGLK 355 Query: 365 SLGLK 369 ++G + Sbjct: 356 AMGFR 360 >3WY7-A nrPDB Length = 404 Score = 52.8 bits (125), Expect = 3e-07, Method: Composition-based stats. Identities = 28/199 (14%), Positives = 57/199 (28%), Gaps = 28/199 (14%) Query: 110 LEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQDPTFPAY 169 L GN L +A L + + S G +++ L L G I + + Sbjct: 96 LVTGNTELHEAFEHQLASFLG-AESALVFSSGYTANLGALVALSGPGSLIVSDALSHASL 154 Query: 170 IDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVA 229 +D+ + + + T V Sbjct: 155 VDACRLSRARVVVSPHRDVDAVDAALAARTEE------------RAVVV------TESVF 196 Query: 230 SRKQ----LHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGARE--VAIEVSSFS 283 S L L + +G++++ D A+ + + + G + ++ S Sbjct: 197 SADGDLAPLRDLHAVCRRHGALLLVDEAHGLGVRGTRGQGLLHEVGLAGAPDIVMTTTLS 256 Query: 284 KFAGFTGVRLGWSIIPDEL 302 K G G G + P+ + Sbjct: 257 KALGSQG---GAVLGPEAV 272 >3NYS-A nrPDB Length = 367 Score = 52.4 bits (124), Expect = 4e-07, Method: Composition-based stats. Identities = 38/274 (13%), Positives = 86/274 (31%), Gaps = 33/274 (12%) Query: 108 YGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSD-ISRLQLLLGSNVTIAVQDPTF 166 Y L L +A+ + ++G + I ++ L +G + T+ Sbjct: 31 YILGPEVTELEDRLADFVGAKYCIS-----CANGTDALQIVQMALGVGPGDEVITPGFTY 85 Query: 167 PAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTG 226 A ++ ++G + + + N+ + + A+TPRT I P Sbjct: 86 VATAETVALLGAKPVYVDIDPRTYNL--------DPQLLEAAITPRTKAII------PVS 131 Query: 227 YVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFA 286 + A G +I D+A +F + + + +SF Sbjct: 132 LYGQCADFDAINAIASKYGIPVIEDAA-QSFGASYKGKRSCNLS-----TVACTSF---- 181 Query: 287 GFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIR 346 F LG +++N + +I + + + G + L + + Sbjct: 182 -FPSAPLG-CYGDGGAIFTNDDELATAIRQIARHGQDRRYHHIRVGVNSRLDTLQAAILL 239 Query: 347 SVNNYYKENRKILMDTLVSLGLKVYG-GVNAPYL 379 ++E + L + G+ P++ Sbjct: 240 PKLEIFEEEIALRQKVAAEYDLSLKQVGIGTPFI 273 >1IBJ-A nrPDB Length = 464 Score = 52.1 bits (123), Expect = 6e-07, Method: Composition-based stats. Identities = 42/253 (16%), Positives = 86/253 (33%), Gaps = 29/253 (11%) Query: 6 FFSSASPLCSSPSKIPKASLDFEMKKLGGSTKLVRNVNLEKLKNNYLFPEINRRELEH-- 63 S SP S SK+P +E K++ N +EK + +N Sbjct: 23 LISKNSPTSVSISKVPT----WEKKQISNRNSFKLNCVMEKSVDGQTHSTVNNTTDSLNT 78 Query: 64 --IEKHPNVQ--LISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRG-YGLEQGNKTLR 118 I++ +V L++L D + +++ + A G Y + R Sbjct: 79 MNIKEEASVSTLLVNL---DNKFDPFDAMSTPLYQTATFKQPSAIENGPYDYTRSGNPTR 135 Query: 119 KAIAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQ 178 A+ + K++ F + +S + L+ + I D + G Sbjct: 136 DALESLLAKL--DKADRAFCFTSGMAALSAVTHLIKNGEEIVAGDDVY----------GG 183 Query: 179 TGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLV 238 + + VV A+ P+T +++ SP NP + + ++ Sbjct: 184 SDRLLSQVVPRSGVVVKRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQI---SDIRKIS 240 Query: 239 DFAKTNGSIIIFD 251 + A G++++ D Sbjct: 241 EMAHAQGALVLVD 253 >3BB8-A nrPDB Length = 437 Score = 51.7 bits (122), Expect = 7e-07, Method: Composition-based stats. Identities = 21/145 (14%), Positives = 46/145 (31%), Gaps = 24/145 (16%) Query: 116 TLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRLQLL---------LGSNVTIAVQDPTF 166 A + L V + + G+ +++ L L L + F Sbjct: 62 RFNDAFEKKLGEYLGV-PYVLTTTSGSSANLLALTALTSPKLGVRALKPGDEVITVAAGF 120 Query: 167 PAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTG 226 P ++ ++ G F + V +P N+ + A++ +T I G Sbjct: 121 PTTVNPTIQNGLIPVFVD--------VDIPTYNVNASLIEAAVSDKTKAIMIAHT---LG 169 Query: 227 YVASRKQLHQLVDFAKTNGSIIIFD 251 + ++ ++ D +I D Sbjct: 170 NLFDLAEVRRVAD---KYNLWLIED 191 >4K2M-A nrPDB Length = 443 Score = 51.7 bits (122), Expect = 8e-07, Method: Composition-based stats. Identities = 44/339 (12%), Positives = 105/339 (30%), Gaps = 50/339 (14%) Query: 80 TTEPIPEQIT-SHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFV 138 P+ IT + + + L+ V + + K ++ ++ + Sbjct: 70 PFLPVDRLITNDEVEDILNTLTEVLPTGKFTSGPYLEQFEKVLSTYLHKRY-----VIAT 124 Query: 139 SDGAQSDISRLQLL-LGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPC 197 S G + + L L L + + +F A ++ + G + + + + Sbjct: 125 SSGTDAIMIGLLALGLNPGDEVIMPANSFSATENAVLASGGVPIYVDINPQTFCI----- 179 Query: 198 GPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAF 257 + + A+TP T I P + + A +I D+ Sbjct: 180 ---DPDKIEEAITPYTKFIL------PVHLYGKHSDMQHIRQIANRYKLKVIEDAC---- 226 Query: 258 IEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSN-------GFPI 310 + ++ ++ + K G G + G +E L GF + Sbjct: 227 ----QGIGLTDLGKYADITTLSFNPYKNFGVCG-KAGAIATDNEELAKKCIQFSYHGFEV 281 Query: 311 INDFHRIVTTSFNGASNIAQAGG----LACLSSGGLKEIRSVNNYYKENRKILMDTLVSL 366 +++ FN + QA + LS K + + Y + + L + Sbjct: 282 NVKNKKVINFGFNSKMDNLQAAIGLERMKYLSLNNFKRLFLADRYITQ-----LAELQNK 336 Query: 367 GLKVYGGVNAPYLW----VHFKGSKSWDVFNEILENTHI 401 G ++ ++W + + D+ ++ E+ + Sbjct: 337 GYIELPELSEDHVWHLFPIKVRTEDRADIMTKLNEDFGV 375 >3DR4-A nrPDB Length = 391 Score = 51.3 bits (121), Expect = 9e-07, Method: Composition-based stats. Identities = 23/132 (17%), Positives = 50/132 (37%), Gaps = 16/132 (12%) Query: 123 ETFYRDLHVKSNEVFVSDGAQSDISRLQLL-LGSNVTIAVQDPTFPAYIDSSVIIGQTGH 181 + F VK + + ++G + L + +G + V T+ A +S G T Sbjct: 63 KAFADYCGVK-HAIACNNGTTALHLALVAMGIGPGDEVIVPSLTYIASANSVTYCGATPV 121 Query: 182 FHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFA 241 + + N+ ++ + +TPRT I P + +++ A Sbjct: 122 LVDNDPRTFNL--------DAAKLEALITPRTKAIM------PVHLYGQICDMDPILEVA 167 Query: 242 KTNGSIIIFDSA 253 + + ++I D+A Sbjct: 168 RRHNLLVIEDAA 179 >5TSU-A nrPDB Length = 422 Score = 50.9 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 21/140 (15%), Positives = 46/140 (32%), Gaps = 13/140 (9%) Query: 144 SDISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSF 203 + + LL + I D + G T + + + + Sbjct: 109 AATVTITHLLKAGDQIICMDDVY----------GGTNLYFRQVASEFGLKISFVDCSKIK 158 Query: 204 FPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSP 263 + A+TP T +++ +P NPT V + +V K I++ D+ + + P Sbjct: 159 LLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVH--KHGDIILVVDNTFMSPYFQ-RP 215 Query: 264 RSIYEIPGAREVAIEVSSFS 283 ++ ++ S Sbjct: 216 LALGADISMYSATKYMNGHS 235 >4L0O-H nrPDB Length = 388 Score = 50.5 bits (119), Expect = 2e-06, Method: Composition-based stats. Identities = 29/172 (16%), Positives = 56/172 (32%), Gaps = 23/172 (13%) Query: 93 SNFAHGLSTVEGYRGYGLEQ-GNK---TLRKAIAETFYRDLHVKSNEVFVSDGAQSDISR 148 + + ++GY + GN L + IA+ + G + I Sbjct: 27 QTSTYRQDAIGRHKGYEYSRSGNPTRFALEELIADLEGGVKGFA-----FASGL-AGIHA 80 Query: 149 LQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLA 208 + LL S + + D + G T + + ++ A Sbjct: 81 VFSLLQSGDHVLLGDDVY----------GGTFRLFNQVLVKNGLSCTIIDTSDISQIKKA 130 Query: 209 MTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIED 260 + P T ++ +P+NP + L Q AK +G + I D+ +A Sbjct: 131 IKPNTKALYLETPSNP---LLKITDLAQCASVAKDHGLLTIVDNTFATPYYQ 179 >4U1T-A nrPDB Length = 389 Score = 49.0 bits (115), Expect = 4e-06, Method: Composition-based stats. Identities = 35/215 (16%), Positives = 67/215 (31%), Gaps = 31/215 (14%) Query: 76 GTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYRDLHVKSNE 135 G P +++ A + Y +G R+ + E L Sbjct: 18 SAGTGDVVPPIHVSTTYERRA------QDEPRYFYGRGENPTREELEECLA-GLERAPFA 70 Query: 136 VFVSDGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYM 195 S G Q+ + L L+ + D + G G F ++ V Y Sbjct: 71 TVFSSG-QAAAATLLSLVRPGQCVVSTDDVY---------AGTDGLFDLAARQGVRVRYA 120 Query: 196 PCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYA 255 LA P +++ +P NP V + ++ A G+ ++ D+ +A Sbjct: 121 DLTTPEGIAAALAE-PDLALVWIETPTNPLLTVVD---VAEVSRRAHERGARVVVDNTFA 176 Query: 256 AFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTG 290 + + + P A + + S +K G Sbjct: 177 S--------PVLQQPLALGADVSLYSTTK--SIAG 201 >1CS1-A nrPDB Length = 386 Score = 49.0 bits (115), Expect = 5e-06, Method: Composition-based stats. Identities = 19/167 (11%), Positives = 52/167 (31%), Gaps = 21/167 (12%) Query: 121 IAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTG 180 + + +L + V + G + + L + + G + Sbjct: 56 VVQRALAELEGGAGAVLTNTGMSAIHLVTTVFLKPGDLLVAPHDCY----------GGSY 105 Query: 181 HFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDF 240 + K + + A+ + ++ SP+NP V + ++ Sbjct: 106 RLFDSLAKRGCYRVLFVDQGDEQALRAALAEKPKLVLVESPSNPLLRVVD---IAKICHL 162 Query: 241 AKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAG 287 A+ G++ + D+ + + + P A + + S +K+ Sbjct: 163 AREVGAVSVVDNTFLS--------PALQNPLALGADLVLHSCTKYLN 201 >2DR1-A nrPDB Length = 386 Score = 48.6 bits (114), Expect = 6e-06, Method: Composition-based stats. Identities = 54/359 (15%), Positives = 103/359 (28%), Gaps = 45/359 (12%) Query: 111 EQGNKTLRKA---IAETFYRDLHVKSNEVFVSDGAQSDI--SRLQLLLGSNVTIAV--QD 163 +K RK E L V+ EV + + + I + ++ + + V Sbjct: 45 SHRSKEYRKVHMDTVERLREFLEVEKGEVLLVPSSGTGIMEASIRNGVSKGGKVLVTIIG 104 Query: 164 PTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNN 223 Y + G+ E L P + + N Sbjct: 105 AFGKRYKEVVESNGRKAVVLEYEP-------GKAVKPEDLDDALRKNPDVEAVTITY--N 155 Query: 224 PTGY-VASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSF 282 T V + L +L AK + ++ D+ A D + + SS Sbjct: 156 ETSTGVLNP--LPELAKVAKEHDKLVFVDAVSAMGGADIKF-------DKWGLDVVFSSS 206 Query: 283 SKFAGF-TGVRLG-----WSII----PDELLYSNGFPIINDFHRIVTTSFNGASNIAQAG 332 K G G+ +G + I P+ Y + + +T Sbjct: 207 QKAFGVPPGLAIGAFSERFLEIAEKMPERGWYFDIPLYVKYLKEKESTPSTPPMPQVFGI 266 Query: 333 GLACLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLKVYGGVN----APYLWVHFKGSKS 388 +A + Y++ K++ + + +GL + + G K Sbjct: 267 NVALRIIEKMGGKEKWLEMYEKRAKMVREGVREIGLDILAEPGHESPTITAVLTPPGIKG 326 Query: 389 WDVFNEILENTHIITVPGSGFGPGGEEYLRISGFG--RRDHIVEASKRLQNFFNTRTKH 445 +V+ + + G+G E+ RI G + + I E L+ N K Sbjct: 327 DEVYEAMRKRG---FELAKGYGSVKEKTFRIGHMGYMKFEDIQEMLDNLREVINELKKQ 382 >2OGE-A nrPDB Length = 399 Score = 48.6 bits (114), Expect = 6e-06, Method: Composition-based stats. Identities = 46/258 (17%), Positives = 75/258 (29%), Gaps = 48/258 (18%) Query: 141 GAQSDISRLQLLL-----GSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYM 195 G S + LQL L G + V T+ A + G T E + + + Sbjct: 83 GVNSGMDALQLALRGLGIGPGDEVIVPSHTYIASWLAVSATGATPVPVEPHEDHPTL--- 139 Query: 196 PCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYA 255 + + A+TPRT + P + L + A +G I+ D+A A Sbjct: 140 -----DPLLVEKAITPRTRALL------PVHLYGHPADMDALRELADRHGLHIVEDAAQA 188 Query: 256 AFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGF---TGVRLGWSIIPDELLYSNGFPIIN 312 GAR + + S A F G LG + + + Sbjct: 189 H--------------GARYRGRRIGAGSSVAAFSFYPGKNLG-CFGDGGAVVTGDPELAE 233 Query: 313 DFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKE---NRKIL-------MDT 362 + + G + L +R + R L + Sbjct: 234 RLRMLRNYGSRQKYSHETKGTNSRLDEMQAAVLRIRLAHLDSWNGRRSALAAEYLSGLAG 293 Query: 363 LVSLGLKVYGGVNAPYLW 380 L +GL V P +W Sbjct: 294 LPGIGLPVTAPDTDP-VW 310 >2DKJ-A nrPDB Length = 407 Score = 48.2 bits (113), Expect = 7e-06, Method: Composition-based stats. Identities = 55/320 (17%), Positives = 88/320 (27%), Gaps = 32/320 (10%) Query: 104 GYRGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQD 163 G R YG + + E V G+Q++++ L+ T+ Sbjct: 57 GARYYGGCEVIDRVESLAIERAKALFGAAWANVQPHSGSQANMAVYMALMEPGDTLM--- 113 Query: 164 PTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGP--NNSFFPDLAMTPRTDVIFFCSP 221 + G +F K K + P + LA+ R VI Sbjct: 114 -GMDLAAGGHLTHGSRVNFSGKLYKVVSYGVRPDTELIDLEEVRRLALEHRPKVIV---- 168 Query: 222 NNPTGYVASRK--QLHQLVDFAKTNGSIIIFDSAY-AAFIEDGSPRSIYEIPGAREVAIE 278 G A + + A G+ ++ D A+ A + G + + Sbjct: 169 ---AGASAYPRFWDFKAFREIADEVGAYLVVDMAHFAGLVAAGLHPNPLPYAH-----VV 220 Query: 279 VSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLS 338 S+ K G R G + D L +I F I L Sbjct: 221 TSTTHKT--LRGPRGGLILSNDPELGKRIDKLI--FPGIQGGPLEHVIAGKAVAFFEALQ 276 Query: 339 SGGLKEIRSVNNYYKENRKILMDTLVSLGLK-VYGGVNAPYLWVHFKGSKSW-DVFNEIL 396 E + + EN K L + L G + V GG + V + E L Sbjct: 277 P----EFKEYSRLVVENAKRLAEELARRGYRIVTGGTDNHLFLVDLRPKGLTGKEAEERL 332 Query: 397 ENTHIITV-PGSGFGPGGEE 415 + I F P Sbjct: 333 DAVGITVNKNAIPFDPKPPR 352 >3ECD-A nrPDB Length = 425 Score = 48.2 bits (113), Expect = 8e-06, Method: Composition-based stats. Identities = 53/317 (16%), Positives = 93/317 (29%), Gaps = 32/317 (10%) Query: 104 GYRGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIA--- 160 G R YG + + E R + V GAQ++ + + L T+ Sbjct: 66 GKRYYGGCEFADEVEALAIERVKRLFNAGHANVQPHSGAQANGAVMLALAKPGDTVLGMS 125 Query: 161 VQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCS 220 + + + G+ + + ++ + LA + +I Sbjct: 126 LDAGGHLTHGAKPALSGKWFNALQYGVSRDTML-----IDYDQVEALAQQHKPSLIIAGF 180 Query: 221 PNNPTGYVASRK-QLHQLVDFAKTNGSIIIFDSAY-AAFIEDGSPRSIYEIPGAREVAIE 278 RK + A + G+ ++ D A+ A I G + E + Sbjct: 181 ------SAYPRKLDFARFRAIADSVGAKLMVDMAHIAGVIAAGRHANPVEHAH-----VV 229 Query: 279 VSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLS 338 S+ K G R G+ + DE + + F + L+ Sbjct: 230 TSTTHKT--LRGPRGGFVLTNDEEIAKKINSAV--FPGLQGGPLMHVIAGKAVAFGEALT 285 Query: 339 SGGLKEIRSVNNYYKENRKILMDTLVSLGLK-VYGGVNAPYLWVHFKGSKSWD-VFNEIL 396 I V N + L D L + G+ V GG + L V + + L Sbjct: 286 DDFKTYIDRVLA----NAQALGDVLKAGGVDLVTGGTDNHLLLVDLRPKGLKGAQVEQAL 341 Query: 397 ENTHIITV-PGSGFGPG 412 E I G F P Sbjct: 342 ERAGITCNKNGIPFDPE 358 >5K8B-A nrPDB Length = 403 Score = 47.8 bits (112), Expect = 1e-05, Method: Composition-based stats. Identities = 37/277 (13%), Positives = 92/277 (33%), Gaps = 35/277 (12%) Query: 137 FVSDGAQSDISRLQLL-LGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYM 195 +S G + + + +G+ + V TF A +++ + G F E + Sbjct: 57 LLSSGTAALQTAMMAAGIGAGDEVIVPPFTFVASVEAIFMAGAVPIFAEIDETLCLSPEG 116 Query: 196 PCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYA 255 + +TPRT I N S ++ ++ K + +++ D+ Sbjct: 117 ---------IEAVITPRTKAI------NLVHMCGSMAKMDEIKAICKKHNLVLLEDAC-Q 160 Query: 256 AFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFH 315 A +++ I + SF T G I + +Y N + H Sbjct: 161 AIGGSYKGQALGTIGD-----VGCYSFDSVKTITCGEGGAVITNNTEIYDNAHMFSDHGH 215 Query: 316 RIVTTSFNGASNIAQAGGL------ACLSSGGLKEIRSVNNYYKENRKILMDT---LVSL 366 + S+ A L L+++ ++ + ++N+K + D + + Sbjct: 216 DHIGKDRGAESHPIMGLNFRISEMNAALGLAQLRKLDTIIDIQRKNKKAIKDAMASIPEV 275 Query: 367 GLK-VYGGVN---APYLWVHFKGSKSWDVFNEILENT 399 + + ++ +++ ++ ++ N Sbjct: 276 SFREIPDPEGDSAGFLSFMLPTEARTQEISKKLAANG 312 >3UWC-A nrPDB Length = 374 Score = 47.4 bits (111), Expect = 1e-05, Method: Composition-based stats. Identities = 28/169 (16%), Positives = 54/169 (31%), Gaps = 18/169 (10%) Query: 86 EQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSD 145 + ++ L+ + + L K E + LH + + V G + Sbjct: 9 SYLERQFADIEPYLNDLREFIKTADFTLGAELEKF--EKRFAALHNAPHAIGVGTGTDAL 66 Query: 146 ISRLQLL-LGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFF 204 ++L +G+ + TF A + + V G T + Y Sbjct: 67 AMSFKMLNIGAGDEVITCANTFIASVGAIVQAGATPVLVDSENGYVIDPE---------K 117 Query: 205 PDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSA 253 + A+T +T I P Y + + L AK + I+ D+ Sbjct: 118 IEAAITDKTKAIM------PVHYTGNIADMPALAKIAKKHNLHIVEDAC 160 >5JAY-A nrPDB Length = 402 Score = 47.4 bits (111), Expect = 1e-05, Method: Composition-based stats. Identities = 39/257 (15%), Positives = 84/257 (32%), Gaps = 38/257 (14%) Query: 117 LRKAIAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDSSVII 176 L +AE + + ++ S G ++++ L L G T+ + ID + + Sbjct: 97 LEDDLAEFVGGFVE-NARALYFSTGYMANLATLTALAGRGTTLFSDALNHASLIDGARLS 155 Query: 177 GQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQ--- 233 + C + A VI + V S Sbjct: 156 RADVQIYPH-----------CDTDALSAMLEASDADVKVIV-------SDTVFSMDGDIA 197 Query: 234 -LHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGARE-VAIEVSSFSKFAGFTGV 291 L +L++ A+ +G+ +I D A+ + R R I + + K AG +G Sbjct: 198 PLPRLLELAEQHGAWLIVDDAHGFGVLGPQGRGAIAQAALRSPNLISIGTLDKAAGVSG- 256 Query: 292 RLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLAC-LSSGGLKEIRSVNN 350 + + ++ ++ + F AS A A ++ L G +E + Sbjct: 257 --AFVAAHETVI----EWLVQRARPYI---FTTASVPAAAHAVSASLRIIGGEEGDARRA 307 Query: 351 YYKE---NRKILMDTLV 364 + ++ + ++ Sbjct: 308 HLQQLIGRTRAMLKATP 324 >4OC9-A nrPDB Length = 424 Score = 47.0 bits (110), Expect = 1e-05, Method: Composition-based stats. Identities = 44/290 (15%), Positives = 89/290 (30%), Gaps = 37/290 (12%) Query: 90 SHMSNFAHGLSTVEGYRGYG--LEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDIS 147 ++ A + E Y + L + +A + V+ G + Sbjct: 36 ENLDQAAARFNLQELGNIYSRLSNPTSDVLGQRLANVEGGAFGIP-----VASGMAACFY 90 Query: 148 RLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDL 207 L L S +A + + G T T K + ++ + Sbjct: 91 ALINLASSGDNVAYSNKIY----------GGTQTLISHTLKNFGIEAREFDIDDLDSLEK 140 Query: 208 AMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIY 267 + T IFF S +NP + + ++ AK + + I D + Sbjct: 141 VIDQNTKAIFFESLSNPQ---IAIADIEKINQIAKKHKIVSICD--------NTVATPFL 189 Query: 268 EIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASN 327 P V + V S SK+ G LG ++I + + ++ + R + S Sbjct: 190 LQPFKHGVDVIVHSLSKYVSGQGTALGGALIERK----DLNDLLKNNDRYKAFNTPDPSY 245 Query: 328 IAQAGGLACLSSGG----LKEIRSVNNYYK-ENRKILMDTLVSLGLKVYG 372 L + +R + +N +L+ L +L +++ Sbjct: 246 HGLNLNTLDLPIFSIRVIITWLRDLGASLAPQNAWLLLQGLETLAVRIEK 295 >1E5F-A nrPDB Length = 404 Score = 47.0 bits (110), Expect = 1e-05, Method: Composition-based stats. Identities = 46/286 (16%), Positives = 92/286 (32%), Gaps = 48/286 (16%) Query: 136 VFVSDGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYM 195 V S G + + + +L + + + + ++ F + + Sbjct: 81 VATSSGMGAIAATVLTILKAGDHLISDECLYGC--THALFEHALTKFGIQVDFINTAIPG 138 Query: 196 PCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYA 255 + M P T +++F +P NPT + +++ + D G ++I D+ + Sbjct: 139 EVKKH--------MKPNTKIVYFETPANPTLKIIDMERVCK--DAHSQEGVLVIADNTF- 187 Query: 256 AFIEDGSPRSIYEIPGAREVAIEVSSFSKFA-GFTGVRLGWSIIPDELLYSNGFPIINDF 314 + P V + V S +K+ G T V G +LL I D Sbjct: 188 -------CSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLICGKADLLQQIRMVGIKDI 240 Query: 315 HRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILMDTLVSL-------- 366 V + + A L + GL + EN + + L S Sbjct: 241 TGSVISPHD-----------AWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYY 289 Query: 367 -------GLKVYGGVNAPY-LWVHFKGSKSWDVFNEILENTHIITV 404 G + Y + F ++ ++L+N +IT+ Sbjct: 290 PGFEDHEGHDIAKKQMRMYGSMITFILKSGFEGAKKLLDNLKLITL 335 >5X5H-A nrPDB Length = 392 Score = 46.7 bits (109), Expect = 2e-05, Method: Composition-based stats. Identities = 45/372 (12%), Positives = 93/372 (25%), Gaps = 60/372 (16%) Query: 100 STVEGYRGYGLEQ----GNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLGS 155 + E +GY + L + +A S G + +++L Sbjct: 42 APNELRKGYEYTRVGNPTIVALEQTVAALEGAKYGRA-----FSSGMAATDILFRIILKP 96 Query: 156 NVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDV 215 I + + + G T + V Y + A+ T + Sbjct: 97 GDHIVLGNDAY----------GGTYRLIDTVFTAWGVEYTVVDTSVVEEVKAAIKDNTKL 146 Query: 216 IFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREV 275 I+ +P NP + + + + ++ D+ +A+ P + Sbjct: 147 IWVETPTNP---ALGITDIEAVAKLTEGTNAKLVVDNTFAS-PYLQQPLKLGAHAVLHST 202 Query: 276 AIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLA 335 + S G G + D+ + + I + F+ LA Sbjct: 203 TKYIGGHSDVVG------GLVVTNDQEMDEELLFMQGGIGPIPS-VFDAYLTARGLKTLA 255 Query: 336 CLSSGGLKEIRSVNNYYKENRK---ILMDTLV-----SLGLKVYGGVNAPYLWVHFKGSK 387 + + + +L L + K + V F G + Sbjct: 256 VRMDRHCDNAEKIAEFLDSRPEVSTVLYPGLKNHPGHEVAAKQMKRFGGM-ISVRFAGGE 314 Query: 388 S--WDVFN--------------EILENTHIITVPGSGFGPG---GEEYLRISGFGRRDHI 428 E L S G + +RIS + I Sbjct: 315 EAAKKFCTSTKLICLAESLGGVESLLEHPATMTHQSAAGSQLEVPRDLVRISIG--IEDI 372 Query: 429 VEASKRLQNFFN 440 + ++ N Sbjct: 373 EDLLADVEQALN 384 >3WGB-A nrPDB Length = 341 Score = 45.9 bits (107), Expect = 4e-05, Method: Composition-based stats. Identities = 49/341 (14%), Positives = 101/341 (29%), Gaps = 41/341 (12%) Query: 108 YGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQDPTFP 167 YG + G L E + DL K +FV G S++ + + Sbjct: 35 YGEDPGVNAL-----EAYGADLLGKEAALFVPSGTMSNLLAVMSHCQRGEGAVLGSAAHI 89 Query: 168 AYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGY 227 ++ + + + PD T ++ + +N G Sbjct: 90 YRYEAQGSAVLGSVALQPVPMQADGSLALADVRAAIAPDDVHFTPTRLVCLENTHN--GK 147 Query: 228 VASRKQLHQLVDFAKTNGSIIIFDSA--YAAFIEDGSPRSIYEIPGAREVAIEVSSFSKF 285 V L ++ + +G + D A + A + G ++ E+ + SK Sbjct: 148 VLPLPYLREMRELVDEHGLQLHLDGARLFNAVVASGH--TVRELVAPFDSVSIC--LSKG 203 Query: 286 AGFTGVRLG-WSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKE 344 G +G + + ++V A +AQAG A + Sbjct: 204 LGAP---VGSLLVGSHAFIA-----RARRLRKMVGGGMRQAGILAQAGLFAL-----QQH 250 Query: 345 IRSVNNYYKENRKIL--MDTLVSLGLKVYGGVNAPYLWVHFKGSKSWDVFNEILENTHII 402 + + + ++ R++ + L + L + +++ +S + + Sbjct: 251 VVRLADDHRRARQLAEGLAALPGIRLDLAQVQTNM-VFLQLTSGESAPLLAFMKAR---- 305 Query: 403 TVPGSGFGPGGEEYLRIS--GFGRRDHIVEASKRLQNFFNT 441 G F GE LR+ D I E + Sbjct: 306 ---GILFSGYGE--LRLVTHLQIHDDDIEEVIDAFTEYLGA 341 >1FC4-A nrPDB Length = 401 Score = 45.5 bits (106), Expect = 5e-05, Method: Composition-based stats. Identities = 50/348 (14%), Positives = 100/348 (28%), Gaps = 40/348 (11%) Query: 104 GYRGYGLEQ-----GNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVT 158 G+G+ G + K + + L ++ + + S ++ + LLG+ Sbjct: 73 DSHGFGMASVRFICGTQDSHKELEQKLAAFLGME-DAILYSSCFDANGGLFETLLGAEDA 131 Query: 159 IAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRT---DV 215 I + ID + + + + + L T D Sbjct: 132 IISDALNHASIIDGVRLCKAKRYRYANNDMQELEARLKEAREAGARHVLIATDGVFSMDG 191 Query: 216 IFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYA-AFIEDGSPRSIYEIPGARE 274 + L + D A ++++ D ++A F+ + S Sbjct: 192 VIAN--------------LKGVCDLADKYDALVMVDDSHAVGFVGENGRGSHEYCDVMGR 237 Query: 275 VAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGL 334 V I + K G G G++ E++ + R S + A I A Sbjct: 238 VDIITGTLGKALG--GASGGYTAARKEVV-----EWLRQRSRPYLFSNSLAPAIVAASIK 290 Query: 335 ACLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSWDVFNE 394 E+R N + + + + G + G +A + V + F Sbjct: 291 VLEMVEAGSELRDR---LWANARQFREQMSAAGFTLAGADHAI-IPVMLGDAVVAQKFAR 346 Query: 395 ILENTHIITVPGSGFGPGGEEYLRI----SGFGRRDHIVEASKRLQNF 438 L+ I G + + RI S + I A + Sbjct: 347 ELQKEGIYVT-GFFYPVVPKGQARIRTQMSAAHTPEQITRAVEAFTRI 393 >5W70-A nrPDB Length = 445 Score = 45.1 bits (105), Expect = 6e-05, Method: Composition-based stats. Identities = 24/145 (16%), Positives = 50/145 (34%), Gaps = 18/145 (12%) Query: 109 GLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRLQLL-LGSNVTIAVQDPTFP 167 G +G ++ + A F V + V + G S + L+ +G+ + V ++ Sbjct: 66 GPYRGTESYERRFARAFAAYNGV-PHCVPAASGTASLMLALEACGIGAGDEVIVPGLSWV 124 Query: 168 AYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGY 227 A + + + F + + P + A+T T I + Sbjct: 125 ASGSTILGVNAVPIFCDVDPDTLCL-----SPEA---VEAAITEHTRAIVVV-------H 169 Query: 228 VASR-KQLHQLVDFAKTNGSIIIFD 251 + S + L A+ +G +I D Sbjct: 170 LYSALADMDALSAIAERHGLPLIED 194 >3AEO-A nrPDB Length = 389 Score = 45.1 bits (105), Expect = 7e-05, Method: Composition-based stats. Identities = 39/280 (13%), Positives = 85/280 (30%), Gaps = 43/280 (15%) Query: 138 VSDGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPC 197 G + S L + D + G T + Sbjct: 80 FGSGMGAISSSTLAFLQKGDHLIAGD----------TLYGCTVSLFTHWLPRFGIEVDLI 129 Query: 198 GPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAF 257 ++ A P T +++ SP NPT V + + G+ ++ D+ + Sbjct: 130 DTSDVEKVKAAWKPNTKMVYLESPANPTCKV---SDIKGIAVVCHERGARLVVDATF--- 183 Query: 258 IEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRI 317 E+ I + S SK+ G +G + I + + Sbjct: 184 -TSPCFLKPLELGAD----IALHSVSKYINGHGDVIG---GVSSAKTAEDIATIKFYRKD 235 Query: 318 VTTSFNGASNIAQAGGLACLSSGGLKEIRS---VNNYYKENRKILMDTLVSLGLKVYGGV 374 + A G+ L + + V + +++ KI+ + GL+ + G Sbjct: 236 AGSLMAPMDAFLCARGMKTLPIRMQIHMENGLKVAKFLEQHEKIVK--VNHPGLESFPGH 293 Query: 375 ----------NAPYLWVHFKGSKSWDVFNEILENTHIITV 404 + +L+ KS++ +++E+ + T+ Sbjct: 294 DIAKKQMTGYGSTFLF----EMKSFEAAKKLMEHLKVCTL 329 >4OTL-A nrPDB Length = 423 Score = 45.1 bits (105), Expect = 7e-05, Method: Composition-based stats. Identities = 54/283 (19%), Positives = 89/283 (31%), Gaps = 45/283 (15%) Query: 104 GYRGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQD 163 G R YG + + + + + ++ V + G+Q++ +L TI Sbjct: 70 GKRYYGGCEYVDVVEQLAIDRVKQLFGAEAANVQPNSGSQANQGVFFAMLKPGDTIM--- 126 Query: 164 PTFPAYIDSSVIIGQ---TGHFHEKTKKYQNVVYMPCGPNNSFFPD----LAMTPRTDVI 216 S+ G G + K+ NVV N D LA + +I Sbjct: 127 -------GMSLAHGGHLTHGSPVNMSGKWFNVVSYGLNENEDIDYDAAEKLANEHKPKLI 179 Query: 217 FFCSPNNPTGYVASRK-QLHQLVDFAKTNGSIIIFDSA-YAAFIEDGSPRSIYEIPGARE 274 + K +L AK+ G+ ++ D A YA I G + Sbjct: 180 VAG------ASAFALKIDFERLAKIAKSVGAYLMVDMAHYAGLIAAGVYPNPVPHAD--- 230 Query: 275 VAIEVSSFSKFAGFTGVRLGWSIIPDEL---LYSNGFPIINDFHRIVTTSFNGASNIAQA 331 ++ K G R G ++ E + S FP I G A Sbjct: 231 --FVTTTTHK--SLRGPRGGVILMKAEYEKPINSAIFPGIQG----------GPLMHVIA 276 Query: 332 GGLACLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLKVYGGV 374 E + EN ++L +TLV GL++ G Sbjct: 277 AKAVAFKEALSPEFKEYQQKVVENARVLAETLVKRGLRIVSGR 319 >1N8P-A nrPDB Length = 393 Score = 44.7 bits (104), Expect = 8e-05, Method: Composition-based stats. Identities = 53/304 (17%), Positives = 102/304 (33%), Gaps = 55/304 (18%) Query: 180 GHFHEKTKKYQNVVYMPCGPNNSFFPDLA------MTPRTDVIFFCSPNNPTGYVASRKQ 233 G + T +Y V G SF DL + T +++ +P NPT V Sbjct: 100 GDVYGGTHRYFTKVANAHGVETSFTNDLLNDLPQLIKENTKLVWIETPTNPTLKV---TD 156 Query: 234 LHQLVDFAKTN----GSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAG-- 287 + ++ D K + I++ D+ + + P I V S +K+ Sbjct: 157 IQKVADLIKKHAAGQDVILVVDNTFLS--------PYISNPLNFGADIVVHSATKYINGH 208 Query: 288 ---FTGV----------RLGWS-----IIPDELLYSNGFPIINDFHRIVTTSFNGASNIA 329 GV RL + IP + H V + A+ IA Sbjct: 209 SDVVLGVLATNNKPLYERLQFLQNAIGAIPSPFDAWLTHRGLKTLHLRVRQAALSANKIA 268 Query: 330 QAGG-----LACLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVH-- 382 + + ++ GLK + + K++R L ++S +K + + Sbjct: 269 EFLAADKENVVAVNYPGLKTHPNYDVVLKQHRDALGGGMISFRIKGGAEAASKFASSTRL 328 Query: 383 FKGSKSWDVFNEILENTHIIT---VPGSGFGPGG--EEYLRISGFGRRDHIVEASKRLQN 437 F ++S +LE ++T +P G ++ +RIS + + + ++ Sbjct: 329 FTLAESLGGIESLLEVPAVMTHGGIPKEAREASGVFDDLVRISVG--IEDTDDLLEDIKQ 386 Query: 438 FFNT 441 Sbjct: 387 ALKQ 390 >2CB1-A nrPDB Length = 412 Score = 44.0 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 42/240 (17%), Positives = 74/240 (30%), Gaps = 29/240 (12%) Query: 77 TGDTTEP-----IPEQITSH--MSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYRDL 129 G +P +P + G GY + KA+ E + L Sbjct: 10 AGLPEDPHGAVGLPIYAVAAYGFKTLEEGQERFATGEGYVYARQKDPTAKALEERL-KAL 68 Query: 130 HVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKY 189 V ++ G + + L LL + + + GQT + Sbjct: 69 EGALEAVVLASGQAATFAALLALLRPGDEVV----------AAKGLFGQTIGLFGQVLSL 118 Query: 190 QNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIII 249 V P + A++ +T +F + NP V L L A+ G ++ Sbjct: 119 MGVTVRYVDPEPEAVRE-ALSAKTRAVFVETVANPALLVPD---LEALATLAEEAGVALV 174 Query: 250 FDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFP 309 D+ + P A + V S +K+A G LG +++ E +P Sbjct: 175 VDNTFG-------AAGALCRPLAWGAHVVVESLTKWASGHGSVLGGAVLSRETELWRNYP 227 >2GMS-A nrPDB Length = 390 Score = 43.6 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 28/185 (15%), Positives = 52/185 (28%), Gaps = 45/185 (24%) Query: 136 VFVSDGAQSDISRLQLL-------LGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKK 188 V VS G+ +++ + L L I V ++ G F + Sbjct: 53 VMVSSGSTANLLMIAALFFTKKPRLKKGDEIIVPAVSWSTTYYPLQQYGLRVKFVDIDIN 112 Query: 189 YQNVVYMPCGPNNSFFPDLAMTPRTDVI----FFCSPNNPTGYVASRKQLHQLVDFAKTN 244 N+ + A+T T I +PNN ++ Sbjct: 113 TLNI--------DIESLKEAVTDSTKAILTVNLLGNPNN----------FDEINKIIGGR 154 Query: 245 GSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAG-----FTGVRLGWSIIP 299 I++ D+ + + + + +FS F G G + Sbjct: 155 DIILLEDNC-ESMGATFNNKCAGTFG-------LMGTFSSFYSHHIATMEG---GCIVTD 203 Query: 300 DELLY 304 DE +Y Sbjct: 204 DEEIY 208 >4J5U-A nrPDB Length = 420 Score = 43.6 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 51/344 (14%), Positives = 103/344 (29%), Gaps = 42/344 (12%) Query: 87 QITSHMSNFAHGLSTVEGYRGYGLEQ---GNKTLRKA---IAETFYRDLHVKSNEVFVSD 140 ++ + L T + GY ++ G + + KA E + + K V Sbjct: 38 FVSPAVLEAQGALLTNKYAEGYPSKRFYNGCEEVDKAENLAIERVKKLFNCKYANVQPHS 97 Query: 141 GAQSDISRLQLLLGSNVTIA---VQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPC 197 G+Q++ + LL T+ + + + + G+ + + + + Sbjct: 98 GSQANQAVYLALLQPGDTVLGMSLDSGGHLTHGAAPNMSGKWFNAVSYSVNKETYL---- 153 Query: 198 GPNNSFFPDLAMTPRTDVIFF---CSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAY 254 + LA + ++ P N + ++VD G+ + D A+ Sbjct: 154 -IDYDEIERLADLHKPKLLIAGFSAYPRN-----IDFAKFREIVD---KVGAYFMADIAH 204 Query: 255 -AAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIIND 313 A + G +S A S+ K G R G + DE + + Sbjct: 205 IAGLVATGEHQSPIPYAHA-----VTSTTHKT--LRGPRGGLILSNDEEIGHKINSAL-- 255 Query: 314 FHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLKV-YG 372 +I A +A L + + + N K L +L G + G Sbjct: 256 ---FPGLQGGPLMHIIAAKAVAFLENLQPEYKSYIQQVI-SNAKALASSLQERGYDILTG 311 Query: 373 GVNAPYLWVHFKGSKSW-DVFNEILENTHIITV-PGSGFGPGGE 414 G + + V + + L+ I F Sbjct: 312 GTDNHIVLVDLRKDGITGKLAANSLDRAGITCNKNAIPFDETSP 355 >4IYO-A nrPDB Length = 397 Score = 42.4 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 39/293 (13%), Positives = 91/293 (31%), Gaps = 48/293 (16%) Query: 80 TTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYRDLHVKSNE---- 135 + + + S+ ++G+ + + R F + V + E Sbjct: 28 PDPSTGAVMPPIYATSTYAQSSPGEHQGFEYSRTHNPTR------FAYERCVAALEGGTR 81 Query: 136 VFVSDGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYM 195 F + S + LL + + D + G F ++ + + Sbjct: 82 AFAFASGMAATSTVMELLDAGSHVVAMDDLY---------GGTFRLFERVRRRTAGLDFS 132 Query: 196 PCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYA 255 + A+ T +++ +P NP + + + A+ +G + + D+ +A Sbjct: 133 FVDLTDPAAFKAAIRADTKMVWIETPTNP---MLKLVDIAAIAVIARKHGLLTVVDNTFA 189 Query: 256 AFIEDGSPRSIYEIPGAREVAIEVSSFSKFAG----FTGVRLGWSIIPDELLYSNGFPII 311 + + + P + + V S +K+ G G +++ D + + Sbjct: 190 S--------PMLQRPLSLGADLVVHSATKYLNGHSDMVG---GIAVVGDNAELAEQMAFL 238 Query: 312 NDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILMDTLV 364 + V F+ L+ GLK + + EN L L Sbjct: 239 QNSIGGVQGPFDSF-----------LALRGLKTLPLRMRAHCENALALAQWLE 280 >6MRE-A nrPDB Length = 420 Score = 42.4 bits (98), Expect = 5e-04, Method: Composition-based stats. Identities = 31/207 (14%), Positives = 64/207 (30%), Gaps = 29/207 (14%) Query: 133 SNEVFVSDGAQSDISRL-----QLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTK 187 + E+ G I+ + + + I + + Sbjct: 99 AEELVFVAGTTEGINLVANSWGNSNVRAGDNIII--------SQMEHHANIVPWQMLCAR 150 Query: 188 KYQNVVYMPCGPNNSFFPDLAMT---PRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTN 244 + +P P+ + + T +T ++ +N G + L +++ A + Sbjct: 151 VGAELRVIPLNPDGTLQLETLPTLFDEKTRLLAITHVSNVLG---TENPLAEMITLAHQH 207 Query: 245 GSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLY 304 G+ ++ D A A P + + + V S K G TG +G + E L Sbjct: 208 GAKVLVDGAQAVM---HHPVDVQAL----DCDFYVFSGHKLYGPTG--IG-ILYVKEALL 257 Query: 305 SNGFPIINDFHRIVTTSFNGASNIAQA 331 P I T S + + +A Sbjct: 258 QEMPPWEGGGSMIATVSLSEGTTWTKA 284 >1SVV-A nrPDB Length = 359 Score = 42.0 bits (97), Expect = 5e-04, Method: Composition-based stats. Identities = 25/152 (16%), Positives = 50/152 (32%), Gaps = 11/152 (7%) Query: 103 EGYRGYG-LEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAV 161 + GYG K R I E R ++ F+S G Q+++ L L + Sbjct: 40 TQHAGYGQDSHCAKAAR-LIGELLER---PDADVHFISGGTQTNLIACSLALRPWEAVIA 95 Query: 162 QDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSP 221 + ++ I TGH + + + +++ Sbjct: 96 TQLGHISTHETGAI-EATGHKVVTAPCPDGKLRVADIESALHENRSEHMVIPKLVYI--- 151 Query: 222 NNPT--GYVASRKQLHQLVDFAKTNGSIIIFD 251 +N T G ++++L + K +G + D Sbjct: 152 SNTTEVGTQYTKQELEDISASCKEHGLYLFLD 183 >2E7J-A nrPDB Length = 371 Score = 41.7 bits (96), Expect = 8e-04, Method: Composition-based stats. Identities = 47/348 (13%), Positives = 92/348 (26%), Gaps = 48/348 (13%) Query: 114 NKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQDPT--FPAYID 171 + I + L + V++GA+ + L V D + +Y+ Sbjct: 52 TPPIHDFIHNQLPKFLGC--DVARVTNGAREAKFAVMHSLAKKDAWVVMDENCHYSSYVA 109 Query: 172 SSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFF--PDLAMTPRTDVIFFCSPNNPTGYVA 229 + G KT P N + + P G Sbjct: 110 AER-AGLNIALVPKTDY----PDYAITPENFAQTIEETKKRGEVVLALITY---PDGNYG 161 Query: 230 SRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFT 289 + + ++ ++ + AYA P S+ EI V S K + Sbjct: 162 NLPDVKKIAKVCSEYDVPLLVNGAYA---IGRMPVSLKEIGADF----IVGSGHKSMAAS 214 Query: 290 GVRLGWSIIPD---ELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIR 346 G +G + + E++ N ++ + GA+ I + + Sbjct: 215 GP-IGVMGMKEEWAEIVLRRSEKYKNKEVELLGCTARGATIITLMASFPHVRERIKRWDE 273 Query: 347 SVNNYYKENRKILMDTLVSLGLKVY--GGVNAPYLWVHF--------KGSKSWDVFNEIL 396 V E + + LG+K N ++ H K L Sbjct: 274 EV-----EKARRFAAEMEKLGIKQLGDNPHNHDLMFFHAEVLYEISKKAKGGRFFLYREL 328 Query: 397 ENTHII-TVPGSGFGPGGEEYLRIS-GFGRRDHIVEASKRLQNFFNTR 442 ++ I PG Y ++S + + + Sbjct: 329 KSRKIHGIKPGL------TRYFKLSTYGLSDEEVDYVLNAFKEIIEKY 370 >6C9E-A nrPDB Length = 422 Score = 41.3 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 36/250 (14%), Positives = 82/250 (32%), Gaps = 22/250 (8%) Query: 85 PEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYRDLHVK-SNEVFVSDGAQ 143 P+ + ++ F ++ + L + +A R ++ + E G Sbjct: 52 PKAVIDAIAQFYEKDNSNVHRGVHALSVRATEMYEAARAKVKRFINARSPRECIFVRGTT 111 Query: 144 SDISRL-QLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNS 202 I+ + Q L+ I + +++ I +K V + Sbjct: 112 EAINLVAQSLVAP--RILPDEEILITHMEHHSNIVPWQMVCKKMGCKLQVAPISLNGEVI 169 Query: 203 FFP-DLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDG 261 + + T ++ +N G + + ++ A G+ ++ D G Sbjct: 170 LEEFERKLNENTKMVAINYASNSLGTI---NPVKTMIKMAHEVGAKVLLD---------G 217 Query: 262 SPRSIYEIPGAREVAIEVSSFS--KFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVT 319 + + + I +++ + +FS K G TG+ + W E L ++ P I + Sbjct: 218 AQATAHLIVDVQDLDCDFYAFSGHKMYGPTGIGVLWG---KEELLNSMTPYQGGGEMINS 274 Query: 320 TSFNGASNIA 329 SF A Sbjct: 275 VSFEATEYAA 284 >5VMB-A nrPDB Length = 425 Score = 41.3 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 52/330 (15%), Positives = 88/330 (26%), Gaps = 40/330 (12%) Query: 104 GYRGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQD 163 G R YG + + + + V G+Q++ + LL T+ Sbjct: 68 GKRYYGGCEFVDVIEQMAIDRAKELFGADYANVQPHAGSQANSAVYLALLNPGDTVL--- 124 Query: 164 PTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFF--PDLAMTPRTDVIFFCSP 221 + G F KT + LA+ + +I Sbjct: 125 -GMSLAHGGHLTHGAKVSFSGKTYNAVQYGLNAETGEIDYEEVERLALEHKPRMIVAGF- 182 Query: 222 NNPTGYVASR-KQLHQLVDFAKTNGSIIIFDSAY-AAFIEDGSPRSIYEIPGAREVAIEV 279 SR + D A G+ + D A+ A + G + +I Sbjct: 183 -----SAYSRVVDWQRFRDIADKVGAYLFVDMAHVAGLVAAGVYPNPVQIADVTTTTTH- 236 Query: 280 SSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLA-CLS 338 K G R G + I V G + A C Sbjct: 237 ----KT--LRGPRSGLILAKA------NEEIEKKLQSAVFPGNQGGPLMHAIAAKAICFK 284 Query: 339 SGGLKEIRSVNNYYKENRKILMDTLVSLGLKVYGG--VNAPYLWVHFKGSKSWDVFNEIL 396 + ++ +N + + + ++ G V G N +L K + + L Sbjct: 285 EAMSDDFKAYQQQVVKNAQAMAEVFIARGYDVVSGGTDNHLFLLSLIKQDVTGKDADAWL 344 Query: 397 ENTHIITV-------PGSGFGPGGEEYLRI 419 HI P S F G +RI Sbjct: 345 GAAHITVNKNSVPNDPRSPFVTSG---IRI 371 >5W1B-A nrPDB Length = 467 Score = 40.9 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 49/261 (18%), Positives = 81/261 (31%), Gaps = 45/261 (17%) Query: 226 GYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAI--EVSSFS 283 G S L ++ + AK +G ++ DSA F E+ + P + I + Sbjct: 198 GQPVSMSNLKEVYEIAKQHGIFVVMDSA--RFCENAYFIKARD-PKYKNATIKEVIFDMY 254 Query: 284 KFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRI---VTTSFNGASNIAQAGGLA----- 335 K+A L S D LL G I D I GGLA Sbjct: 255 KYADA----LTMSAKKDPLLNIGGLVAIRDNEEIFTLARQRCVPMEGFVTYGGLAGRDMA 310 Query: 336 CLSSGGLKEIRSVNNYYKENR-KILMDTLVSLGLKVYGGVNAPYLWVHF----KGSKSWD 390 + G + +Y+ + K L D L G+ + ++V Sbjct: 311 AMVQGLEEGTEEEYLHYRIGQVKYLGDRLREAGIPIQYPTGGHAVFVDCKKLVPQIPGDQ 370 Query: 391 VFNE-----ILENTHIITVPGSGF--GPGGE---------EYLRISGFG------RRDHI 428 + + + + V F G E++R++ D+I Sbjct: 371 FPAQAVINALYLESGVRAVEIGSFLLGRDPATGEQKHADMEFMRLTIARRVYTNDHMDYI 430 Query: 429 VEASKRLQNFFNT-RTKHFTY 448 +A L+ F T + F Y Sbjct: 431 ADALIGLKEKFATLKGLEFEY 451 >3NDN-A nrPDB Length = 414 Score = 40.9 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 19/118 (16%), Positives = 45/118 (38%), Gaps = 13/118 (11%) Query: 138 VSDGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPC 197 + G + + L LLG+ + + + G + V + Sbjct: 102 TASGMAAVFTSLGALLGAGDRLV----------AARSLFGSCFVVCSEILPRWGVQTVFV 151 Query: 198 GPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYA 255 ++ + A++ T +FF +P+NP + S + + + A G+ ++ D+ +A Sbjct: 152 DGDDLSQWERALSVPTQAVFFETPSNP---MQSLVDIAAVTELAHAAGAKVVLDNVFA 206 >1WYV-B nrPDB Length = 474 Score = 40.9 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 59/402 (14%), Positives = 124/402 (30%), Gaps = 58/402 (14%) Query: 29 MKKLGGSTKLVRNVNLEKLKNNYLFPEINR----RELEHIEKHP-NVQLISLGTGDTTEP 83 +K + + L+ +L ++ PE++ R + + V G T Sbjct: 20 VKAVPKAEDLIPKEHLREVPPR--LPEVDELTLVRHYTGLSRRQVGVDTTFYPLGSCTMK 77 Query: 84 IPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQ 143 ++ + L + R QG L + E + + + + GA Sbjct: 78 YNPKLHEEAARLFADLHPYQDPR---TAQGALRLMWELGEYLKALTGMDAITLEPAAGAH 134 Query: 144 SDISRLQLLL------GSNVT---IAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVY 194 +++ + ++ G T + V D + ++ + G + + + Sbjct: 135 GELTGILIIRAYHEDRGEGRTRRVVLVPDSAHGSNPATASMAGY---------QVREIPS 185 Query: 195 MPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAY 254 P G + + P + +PN T + R+ L + K G + +D A Sbjct: 186 GPEGEVDLEALKRELGPHVAALMLTNPN--TLGLFERRILE-ISRLCKEAGVQLYYDGAN 242 Query: 255 ----------AAFIEDGSP---RSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDE 301 D + +P K +P Sbjct: 243 LNAIMGWARPGDMGFDVVHLNLHKTFTVPHGGGGPGSGPVGVKAHLAP-------YLPVP 295 Query: 302 LLYSNGFPIINDFHRIVT----TSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRK 357 L+ DF R + SF G + +A A + + GL+ ++ N + Sbjct: 296 LVERGEEGFYLDFDRPKSIGRVRSFYG-NFLALVRAWAYIRTLGLEGLKKAAALAVLNAR 354 Query: 358 ILMDTLVSLGLKVYGGVNAPYLWVHFK--GSKSWDVFNEILE 397 L + L G +V + + +V G ++ D+ +LE Sbjct: 355 YLKELLKEKGYRVPYDGPSMHEFVAQPPEGFRALDLAKGLLE 396 >5I92-A nrPDB Length = 435 Score = 40.1 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 42/273 (15%), Positives = 84/273 (30%), Gaps = 24/273 (8%) Query: 137 FVSDGAQSDISRLQLLLG--SNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVY 194 VS G ++ +S ++L G +I + + + DS ++ +G V Sbjct: 119 MVSSGTEATMSAIRLARGYTGRDSIIKFEGCYHGHSDSLLVKAGSGALTFGVPNSPGVPA 178 Query: 195 --------MPCGPNNSFFPDLAMTPRTDVIFFCSP--NNPTGYVASRKQLHQLVDFAKTN 244 +P + L + P N + L L + + Sbjct: 179 AFAKHTLTLPFNDIEAVRKTLGEVGKEVACIIVEPVAGNMNCVPPAPGFLEGLREACDEH 238 Query: 245 GSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLY 304 G ++IFD F ++ V ++S+F K G G+ +G E++ Sbjct: 239 GVVLIFDEVMTGF-----RVALGGAQAYYGVTPDLSTFGKIIG-GGMPVGAFGGKREIM- 291 Query: 305 SNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKEN-RKILMDTL 363 I+ + + +A A GL L Y L Sbjct: 292 ----QQISPLGPVYQAGTLSGNPLAMAAGLTTLRLISRPGFHDELTAYTTRMLDGLQQRA 347 Query: 364 VSLGLKVYGGVNAPYLWVHFKGSKSWDVFNEIL 396 + G+ ++F G+ + F +++ Sbjct: 348 DAAGIPFVTTQAGGMFGLYFSGADAIVTFEDVM 380 >6JEQ-A nrPDB Length = 675 Score = 39.7 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 16/84 (19%), Positives = 27/84 (32%), Gaps = 5/84 (5%) Query: 200 NNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIE 259 N + P P + P+NP + +L +L+ G +I D Y + Sbjct: 233 NWGYDPQNYNVPEGS--YSTDPHNPAARIL---ELKRLIQKLHARGLRVIMDVVYNHVYD 287 Query: 260 DGSPRSIYEIPGAREVAIEVSSFS 283 +PG +FS Sbjct: 288 GYLIHFTKLVPGYYLRYKADRTFS 311 >1B9H-A nrPDB Length = 388 Score = 39.7 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 24/120 (20%), Positives = 44/120 (36%), Gaps = 15/120 (12%) Query: 138 VSDGAQSDISRLQLL-LGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMP 196 V++G + LQ++ +G + V TF + ++ +G + N+ Sbjct: 59 VTNGTHALELALQVMGVGPGTEVIVPAFTFISSSQAAQRLGAVTVPVDVDAATYNL---- 114 Query: 197 CGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAA 256 P A+TPRT VI P + L + G ++ D+A+A Sbjct: 115 -DPEA---VAAAVTPRTKVIM------PVHMAGLMADMDALAKISADTGVPLLQDAAHAH 164 >3N0L-A nrPDB Length = 417 Score = 39.3 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 56/322 (17%), Positives = 100/322 (31%), Gaps = 35/322 (10%) Query: 104 GYRGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQD 163 G R YG + + E + + K V + G+Q++ L+ I D Sbjct: 59 GKRYYGGCEFVDEIETLAIERCKKLFNCKFANVQPNSGSQANQGVYAALINPGDKILGMD 118 Query: 164 PTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNN 223 + ++ + +G +E V + + ++A + +I Sbjct: 119 LSHGGHLTHGAKVSSSGKMYESCFY---GVELDGRIDYEKVREIAKKEKPKLIV------ 169 Query: 224 PTGYVASRK--QLHQLVDFAKTNGSIIIFDSAY-AAFIEDGSPRSIYEIPGAREVAIEVS 280 G A + + + A G+ + D A+ A + G S + + S Sbjct: 170 -CGASAYARVIDFAKFREIADEIGAYLFADIAHIAGLVVAGEHPSPFPYAH-----VVSS 223 Query: 281 SFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSG 340 + K G R G + DE L I F I A Sbjct: 224 TTHKT--LRGPRGGIIMTNDEELAKKINSAI--FPGIQGGPLMHVI----AAKAVGFKFN 275 Query: 341 GLKEIRSVNNYYKENRKILMDTLVSLGLK-VYGGVNAPYLWVHFKGSKSWDVFNEI-LEN 398 E + + N ++L + L+ K V G + + + F + ++ L N Sbjct: 276 LSDEWKVYAKQVRTNAQVLANVLMDRKFKLVSDGTDNHLVLMSFLDREFSGKDADLALGN 335 Query: 399 THI----ITVPG---SGFGPGG 413 I TVPG S F G Sbjct: 336 AGITANKNTVPGEIRSPFITSG 357 >5LL2-A nrPDB Length = 480 Score = 39.3 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 48/292 (16%), Positives = 84/292 (28%), Gaps = 34/292 (11%) Query: 160 AVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFC 219 + Y DS + + P SF P T + Sbjct: 196 MLPSVVHVPYPDSYRTYPGETEHDVSLRYFNEFK----KPFESFLP----ADETACVLIE 247 Query: 220 SPNNPT----GYVASRKQLHQLV-DFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGARE 274 P G + + ++ QLV F +G + D G +I + Sbjct: 248 ----PIQGDGGIIKAPEEYMQLVYKFCHEHGILFAIDEVNQGLGRTGKMWAIQQFKDIEP 303 Query: 275 VAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGL 334 + S K +G+ L I E++ S P + TT+ N + A L Sbjct: 304 D---LMSVGKSLA-SGMPLSAVIGKKEVMQSLDAPAH-----LFTTAGNPVCSAASLATL 354 Query: 335 ACLSSGGLKEIRSVNNYYKENRKI-LMDTLVSLGLKVYGGVNAPYLWVHFK--GSKSWDV 391 + GL E + + Y + R + + +G G+N V D Sbjct: 355 DVIEYEGLVEKSATDGAYAKQRFLEMQQRHPMIGDVRMWGLNGGIELVKDPKTKEPDSDA 414 Query: 392 FNEILENTHIITVPGSGFGPGGEEYLRIS--GFGRRDHIVEASKRLQNFFNT 441 +++ G LR R+ + +A + L + F Sbjct: 415 ATKVIY---YAFAHGVVIITLAGNILRFQPPLVIPREQLDQALQVLDDAFTA 463 >5WT2-A nrPDB Length = 401 Score = 39.3 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 56/400 (14%), Positives = 118/400 (29%), Gaps = 69/400 (17%) Query: 83 PIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGA 142 P ++I +G + + + +A+ + + ++V ++ A Sbjct: 17 PKVKEIMDPFLR--DHYGNPSSLHQFG-TETHPAIAEALDKLYKGINARDIDDVIITSCA 73 Query: 143 QS-------DISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYM 195 + + L I PA + + G V Y+ Sbjct: 74 TESNNWVLKGVYFDECLKKGKNHIVTTVAEHPAVRSTCNFLESLGV---------EVTYL 124 Query: 196 PCGPNNSFFPDL---AMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDS 252 P + S + A+T +T ++ NN TG + + ++ K G + D+ Sbjct: 125 PINEHGSITAEQVREAITEKTALVSVMWANNETGLIFP---IEEIGAICKEKGVLFHTDA 181 Query: 253 AYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIIN 312 + ++ A + S KF G G +G I + + F Sbjct: 182 V------QAIGKIPVDVLKANADFLS-FSAHKFHGPKG--IGGLYIRSGVGLTPLFHGGE 232 Query: 313 DFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILMDTLVSLG----- 367 + + + N + + L+ L + V R L + L+ + Sbjct: 233 HMNGRRSGTLNVPYIVGMGEAMK-LAVEHLDYEKEVVGKL---RDKLEEALLKIPDVMVV 288 Query: 368 ------------LKVYGGVNAPYLW----VHFKGSKSWDVFNEILENTHIITVPGSGFGP 411 + V G LW + S +E LE ++ G+ Sbjct: 289 GDRIHRVPNTTLVSVRGIEGEAMLWDLNRSNIAASTGSACASEDLEANPVMVAIGAS-KE 347 Query: 412 GGEEYLRISGFG---------RRDHIVEASKRLQNFFNTR 442 +R+S + +A+ RL+N ++ Sbjct: 348 LAHTAIRLSLSRFNTEAEIDKTIEVFSQAAVRLRNISSSY 387 >3RUY-A nrPDB Length = 392 Score = 39.0 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 36/295 (12%), Positives = 86/295 (29%), Gaps = 43/295 (14%) Query: 158 TIAVQDPTFPAYI-DSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVI 216 I V + F + + + ++ +P G + A+TP T Sbjct: 129 EIIVCEDNFHGRTMGAVSMSSNEEYKRGFGPMLPGIIVIPYG--DLEALKAAITPNTAAF 186 Query: 217 FF---------CSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIY 267 P P G L + ++ K + + D G Sbjct: 187 ILEPIQGEAGINIP--PAG------FLKEALEVCKKENVLFVADEIQTGLGRTGK-VFAC 237 Query: 268 EIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASN 327 + V ++ K G + + ++L F S G + Sbjct: 238 DW---DNVTPDMYILGKALGGGVFPISCAAANRDILGV--------FEPGSHGSTFGGNP 286 Query: 328 IAQAGGLACLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFKGSK 387 +A A +A L +++ + E + + + + G L++ + ++ Sbjct: 287 LACAVSIAALEVLEEEKLTERSLQLGEKLVGQLKEIDNPMITEVRGKG---LFIGIELNE 343 Query: 388 SWDVFNEILENTHIITVPGSGFGPGGEEYLRIS--GFGRRDHIVEASKRLQNFFN 440 + E L+ ++ E +RI+ + + A ++++ + Sbjct: 344 PARPYCEQLKAAGLL------CKETHENVIRIAPPLVISEEDLEWAFQKIKAVLS 392 >2EH6-A nrPDB Length = 375 Score = 39.0 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 33/212 (15%), Positives = 63/212 (29%), Gaps = 29/212 (13%) Query: 230 SRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFT 289 S L +L + K ++I D G + +V + +K G Sbjct: 191 SEDFLSKLQEICKEKDVLLIIDEVQTGIGRTGEFYAYQHFNLKPDVI----ALAKGLG-G 245 Query: 290 GVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVN 349 GV +G + +E+ S ++F G +AG + + E+ + Sbjct: 246 GVPIGAILAREEVAQSFTPGSH-------GSTFGGNPLACRAGTVV------VDEVEKLL 292 Query: 350 NYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSWDVFNEILENTHIITVPGSGF 409 + +E + L LG G G + + + G Sbjct: 293 PHVREVGNYFKEKLKELGKGKVKGRGLML------GLELERECKDYVLK---ALEKGLLI 343 Query: 410 GPGGEEYLRI--SGFGRRDHIVEASKRLQNFF 439 + LR +++HI A L+ Sbjct: 344 NCTAGKVLRFLPPLIIQKEHIDRAISVLREIL 375 >5IJG-A nrPDB Length = 427 Score = 39.0 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 14/113 (12%), Positives = 36/113 (31%), Gaps = 4/113 (3%) Query: 132 KSNEVFVSDGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQN 191 + S G + + L + I P + +++ +F + + + Sbjct: 98 AESAALFSSGMSAIATTLFAFVRPGDVILHSQPLYGG--TETLLAKTFFNFGVEAVAFAD 155 Query: 192 VVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTN 244 V+ + + R VI +P NPT + + ++ + + Sbjct: 156 GVHEATIEKAA--EEALAKGRVSVILIETPANPTNSIVDVAAVRRVAEKIEAR 206 >5WGB-A nrPDB Length = 426 Score = 38.6 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 49/375 (13%), Positives = 115/375 (30%), Gaps = 52/375 (13%) Query: 81 TEPIPEQITSHMSNFA--HGLSTVEGYRGYGLE--QGNKTLRKAIAETFYRDLHVKSNEV 136 T P+ ++ M + + + YG E + R+ +A + E+ Sbjct: 35 TTPLDPRVLDAMLPYLINYYGNPHSRTHAYGWESEAAMERARQQVASL----IGADPREI 90 Query: 137 FVSDGAQS----DISRLQLLLGSNVTIAVQDPT-FPAYIDSSVIIGQTGHFHEKTKKYQN 191 + GA I + S + T +DS + G + Sbjct: 91 IFTSGATESNNIAIKGVARFYRSRKKHLITTQTEHKCVLDSCRSLEAEGF------QVTY 144 Query: 192 VVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFD 251 + G + + A+ P T ++ + NN G ++ + ++ + D Sbjct: 145 LPVQKSGIIDLKELEAAIQPDTSLVSVMTVNNEIGV---KQPIAEIGRICSSRKVYFHTD 201 Query: 252 SAYAAFIEDGSPRSIYEIP-GAREVAIEVSSFS--KFAGFTGVRLGWSIIPDELLYSNGF 308 +A +++ +IP ++ I++ S S K G GV + I + Sbjct: 202 AA----------QAVGKIPLDVNDMKIDLMSISGHKIYGPKGVGAIY-IRRRPRVRVEAL 250 Query: 309 PIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKEN-RKILMDTLVSLG 367 R + + + G ++ ++ + E + +M +L + Sbjct: 251 QSGGGQERGMRSGTVPTPLVVGLGAACEVAQQEMEYDHKRISKLSERLIQNIMKSLPDV- 309 Query: 368 LKVYGGVNAPYLWVHFKGSKSWDVF-----NEILENTHIITVPGSGFGPGG--EEYLRIS 420 + + H+ G + + ++ + GS Y+ + Sbjct: 310 VMNGDPKH------HYPGCINLSFAYVEGESLLMALKDVALSSGSACTSASLEPSYV-LR 362 Query: 421 GFGRRDHIVEASKRL 435 G + + +S R Sbjct: 363 AIGTDEDLAHSSIRF 377 >4KAM-A nrPDB Length = 453 Score = 38.6 bits (88), Expect = 0.006, Method: Composition-based stats. Identities = 33/153 (21%), Positives = 53/153 (34%), Gaps = 22/153 (14%) Query: 136 VFVSDGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGH-FHEKTKKYQNVVY 194 +F+S G ++ + L G+ I S + G T + FH K V Sbjct: 96 LFLSSGQAAETFAILNLAGAGDHIVS----------SPRLYGGTYNLFHYSLAKLGIEVS 145 Query: 195 MPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAY 254 P+N A+ P T F + +NP + + A NG +I D+ Sbjct: 146 FVDDPDNLDSWQAAVRPNTKAFFGETISNPQ---IDLLDTPGVAEVAHRNGIPLIVDN-- 200 Query: 255 AAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAG 287 +P I + I V S +K+ G Sbjct: 201 ----TIATPYLIRPFTQGAD--IVVHSATKYLG 227 >3G8M-A nrPDB Length = 417 Score = 38.6 bits (88), Expect = 0.006, Method: Composition-based stats. Identities = 41/279 (14%), Positives = 79/279 (28%), Gaps = 36/279 (12%) Query: 104 GYRGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQD 163 G R YG + + + + V G+Q++ + LL T+ Sbjct: 61 GKRYYGGCEYVDIVEQLAIDRAKELFGADYANVQPHSGSQANFAVYTALLEPGDTVL--- 117 Query: 164 PTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPR--TDVIFFCSP 221 + G +F K Y V Y + + DL + + Sbjct: 118 -GMNLAHGGHLTHGSPVNF--SGKLYNIVPYGIDATGHIDYADLEKQAKEHKPKMIIGGF 174 Query: 222 NNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAY------AAFIEDGSPRSIYEIPGAREV 275 + +G V ++ + A + G+ + D A+ A + P + + Sbjct: 175 SAYSGVV----DWAKMREIADSIGAYLFVDMAHVAGLVAAGVYPNPVPHAHVVTTTTHKT 230 Query: 276 AIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLA 335 G R G + + + V G + G A Sbjct: 231 ------------LAGPRGGLILA-----KGGSEELYKKLNSAVFPGGQGGPLMHVIAGKA 273 Query: 336 -CLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLKVYGG 373 L E ++ +N K +++ + G KV G Sbjct: 274 VALKEAMEPEFKTYQQQVAKNAKAMVEVFLERGYKVVSG 312 >3GZD-A nrPDB Length = 440 Score = 38.2 bits (87), Expect = 0.008, Method: Composition-based stats. Identities = 49/316 (15%), Positives = 90/316 (28%), Gaps = 49/316 (15%) Query: 81 TEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSD 140 T P+ ++ M+ + Y + K + A E+ + + K ++ + Sbjct: 34 TTPLEPEVIQAMTKAMWE-AWGNPSSPYSAGRKAKDIINAARESLAKMIGGKPQDIIFTS 92 Query: 141 GAQSD----ISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMP 196 G I + +N T + + G HF + ++ ++ Sbjct: 93 GGTESNNLVIHSVVKHFHANQTSKGHTGGHHS-----PVKGAKPHFITSSVEHDSIRLPL 147 Query: 197 C-------------------GPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQL 237 G A+ P T ++ NN TG V ++ Q Sbjct: 148 EHLVEEQVAAVTFVPVSKVSGQTEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEISQR 207 Query: 238 V------DFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGV 291 + A I++ A A G R E G + I KF G Sbjct: 208 IKALNQERVAAGLPPILVHTDAAQAL---GKQRVDVEDLGVDFLTIVGH---KFY---GP 258 Query: 292 RLG--WSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVN 349 R+G + E R IA G A L + + + Sbjct: 259 RIGALYIRGLGEFTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVTQNCEAYEA-- 316 Query: 350 NYYKENRKILMDTLVS 365 + ++ R L + L + Sbjct: 317 -HMRDVRDYLEERLEA 331 >5U24-A nrPDB Length = 382 Score = 38.2 bits (87), Expect = 0.008, Method: Composition-based stats. Identities = 51/285 (17%), Positives = 85/285 (29%), Gaps = 62/285 (21%) Query: 140 DGAQSDISRLQLL-----LGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVY 194 G + + L+L+ N I V T+ A I + E N+ Sbjct: 75 IGVANGLDALRLIIKAYDFKENDEIIVPANTYIASILAITDNKCKPILIEPDINTYNI-- 132 Query: 195 MPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFD--S 252 N + +T +T I G V +++ L + II D Sbjct: 133 ------NPDLIEEKITKKTKAIMVVHLY---GQVCDMEKIQLLAN---KYNLKIIEDCAQ 180 Query: 253 AYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIIN 312 A+ A +D K G G G+S P L + G Sbjct: 181 AHGAIYKD-----------------------KRVGNLGDAAGFSFYPGANLGALG----- 212 Query: 313 DFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLKVYG 372 D I T N AS I A + G K+ ++ + + + LK Sbjct: 213 DAGCICTNDDNFASKI-----RALANYGSHKKYENLYTGLNSRLDEIQAAFLDIKLKYLD 267 Query: 373 GVNAPYLWVHFKGSKSWDVFNEILENTHIITVPGSGFGPGGEEYL 417 N K + + + ++N +II P + F ++ Sbjct: 268 EDNN-------KRKNIANFYLQNIKNENIIL-PSNKFDHVWHLFV 304 >1YJS-A nrPDB Length = 419 Score = 37.8 bits (86), Expect = 0.009, Method: Composition-based stats. Identities = 57/356 (16%), Positives = 101/356 (28%), Gaps = 42/356 (11%) Query: 104 GYRGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQD 163 G R YG + + + E + + V GAQ++++ +L T+ + Sbjct: 57 GRRYYGGCEYVDIVEELARERAKQLFGAEHANVQPHSGAQANMAVYFTVLEHGDTVLGMN 116 Query: 164 PTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCG--PNNSFFPDLAMTPRTDVIFFCSP 221 + ++ G +F + P + + A R +I Sbjct: 117 LSHGGHLTH----GSPVNFSGVQYNFVAYGVDPETHVIDYDDVREKARLHRPKLIVAA-- 170 Query: 222 NNPTGYVASR-KQLHQLVDFAKTNGSIIIFDSAY-AAFIEDGSPRSIYEIPGAREVAIEV 279 R + + A G+ ++ D A+ A + G + +P A V Sbjct: 171 ----ASAYPRIIDFAKFREIADEVGAYLMVDMAHIAGLVAAGLHPNP--VPYAHFVTTTT 224 Query: 280 SSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSS 339 G R G I+ E I F I A Sbjct: 225 HQT-----LRGPRGG-MILCQEQFAKQIDKAI--FPGIQGGPLMHVI----AAKAVAFGE 272 Query: 340 GGLKEIRSVNNYYKENRKILMDTLVSLGLK-VYGGVNAPYLWVHFKGSKSWDV-FNEILE 397 + ++ +N K L L + G V GG + L V + + ++L+ Sbjct: 273 ALQDDFKAYAKRVVDNAKRLASALQNEGFTLVSGGTDNHLLLVDLRPQQLTGKTAEKVLD 332 Query: 398 NTHIITV-------PGSGFGPGGEEYLRISGF--GRRDHIVEASKRLQNFFNTRTK 444 I P S F G +RI R +E + K Sbjct: 333 EVGITVNKNTIPYDPESPFVTSG---IRIGTAAVTTRGFGLEEMDEIAAIIGLVLK 385 >3I5T-A nrPDB Length = 476 Score = 37.4 bits (85), Expect = 0.012, Method: Composition-based stats. Identities = 47/311 (15%), Positives = 86/311 (27%), Gaps = 44/311 (14%) Query: 87 QITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDI 146 +I M++ + Y L + IA DL N +F + G + + Sbjct: 74 EIVDAMAH--QAMVLPYASPWYMATSPAARLAEKIATLTPGDL----NRIFFTTGGSTAV 127 Query: 147 SRLQLLLG---------SNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPC 197 I V+ + + Q+ + Sbjct: 128 DSALRFSEFYNNVLGRPQKKRIIVRYDGYHGSTALTAACTGRTGNWPNFDIAQDRISFLS 187 Query: 198 GPN---------NSFFPDL---------AMTPRTDVIFFCSPNNPTGYVA--SRKQLHQL 237 PN +F DL ++ P T F P +G V + Sbjct: 188 SPNPRHAGNRSQEAFLDDLVQEFEDRIESLGPDTIAAFLAEPILASGGVIIPPAGYHARF 247 Query: 238 VDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSI 297 + + + I D F G + V ++ +F+K GV G+ Sbjct: 248 KAICEKHDILYISDEVVTGF---GRCGEWFASEKVFGVVPDIITFAK-----GVTSGYVP 299 Query: 298 IPDELLYSNGFPIINDFHRIVTTSFNGASNIAQ-AGGLACLSSGGLKEIRSVNNYYKENR 356 + + I+ + + NG + Q A L++ L E + + +E Sbjct: 300 LGGLAISEAVLARISGENAKGSWFTNGYTYSNQPVACAAALANIELMEREGIVDQAREMA 359 Query: 357 KILMDTLVSLG 367 L SL Sbjct: 360 DYFAAALASLR 370 >5TXT-B nrPDB Length = 491 Score = 37.4 bits (85), Expect = 0.013, Method: Composition-based stats. Identities = 28/211 (13%), Positives = 58/211 (27%), Gaps = 35/211 (16%) Query: 232 KQLHQLVDFAKTNGSIIIFDSAYA-------------AFIEDGSPRSIYEIPGARE---- 274 + ++ D A G++ D +A + S P + Sbjct: 205 ADIEKICDLADKYGALTFLDEVHAVGLYGPHGAGVAEHCDFESHRASGIATPKTNDKGGA 264 Query: 275 ------VAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNI 328 V + + K G G G+ +L+ F + ++ Sbjct: 265 KTVMDRVDMITGTLGKSFGSVG---GYVAASRKLI-----DWFRSFAPGFIFTTTLPPSV 316 Query: 329 AQAGGLACLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFKGSKS 388 A ++R+ +++ + LG+ V + + V + Sbjct: 317 MAGATAAIRYQRCHIDLRTSQ---QKHTMYVKKAFHELGIPVI-PNPSHIVPVLIGNADL 372 Query: 389 WDVFNEILENTHIITVPGSGFGPGGEEYLRI 419 ++IL N H I V F R+ Sbjct: 373 AKQASDILINKHQIYVQAINFPTVARGTERL 403 >4WXB-A nrPDB Length = 428 Score = 37.0 bits (84), Expect = 0.018, Method: Composition-based stats. Identities = 35/250 (14%), Positives = 65/250 (26%), Gaps = 21/250 (8%) Query: 104 GYRGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQD 163 G R YG + E + K V G+Q++ + L+ T+ Sbjct: 73 GKRYYGGTAVIDVVETLAIERAKKLFGAKFANVQPHSGSQANAAVYMSLIQPGDTVM--- 129 Query: 164 PTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTD-VIFFCSPN 222 + G F KT + + + LA + + Sbjct: 130 -GMDLSAGGHLTHGAPVSFSGKTYNFVSYNVDKESELLDYDAILAQAKEVRPKLIVAGAS 188 Query: 223 NPTGYVASR-KQLHQLVDFAKTNGSIIIFDSAY-AAFIEDGSPRSIYEIPGAREVAIEVS 280 SR + + A G+ ++ D A+ A + G S + + Sbjct: 189 -----AYSRIIDFAKFREIADAVGAYLMVDMAHIAGLVASGHHPSPVPYAH-----VTTT 238 Query: 281 SFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSG 340 + K G R G + DE + + F + L Sbjct: 239 TTHKT--LRGPRGGLILTDDEDIAKKLNSAV--FPGLQGGPLEHVIAAKAVALKEALDPA 294 Query: 341 GLKEIRSVNN 350 + +V Sbjct: 295 FKEYGENVIK 304 >3GBX-A nrPDB Length = 420 Score = 36.6 bits (83), Expect = 0.020, Method: Composition-based stats. Identities = 56/348 (16%), Positives = 100/348 (28%), Gaps = 51/348 (14%) Query: 104 GYRGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQD 163 G R YG + + + + V G+Q++ + LL T+ Sbjct: 64 GKRYYGGCEYVDVVEQLAIDRAKELFGADYANVQPHSGSQANFAVYTALLQPGDTVL--- 120 Query: 164 PTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPD---LAMTPRTDVIFFCS 220 + G +F K Y V Y + + LA + + Sbjct: 121 -GMNLAQGGHLTHGSPVNF--SGKLYNIVPYGIDESGKIDYDEMAKLAKEHKPKM-IIGG 176 Query: 221 PNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAY------AAFIEDGSPRSIYEIPGARE 274 + +G V ++ + A + G+ + D A+ A + P + + Sbjct: 177 FSAYSGVV----DWAKMREIADSIGAYLFVDMAHVAGLIAAGVYPNPVPHAHVVTTTTHK 232 Query: 275 VAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGL 334 G R G + + + V S G + G Sbjct: 233 T------------LAGPRGGLILA-----KGGDEELYKKLNSAVFPSAQGGPLMHVIAGK 275 Query: 335 A-CLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLKVYGG--VNAPYLWVHFKGSKSWDV 391 A L E + +N K +++ ++ G KV G N +L + + Sbjct: 276 AVALKEAMEPEFKVYQQQVAKNAKAMVEVFLNRGYKVVSGGTENHLFLLDLVDKNLTGKE 335 Query: 392 FNEILENTHIITV-------PGSGFGPGGEEYLRI-SGFGRRDHIVEA 431 + L +I P S F G +RI S R EA Sbjct: 336 ADAALGRANITVNKNSVPNDPKSPFVTSG---IRIGSPAVTRRGFKEA 380 >3OKS-A nrPDB Length = 451 Score = 36.6 bits (83), Expect = 0.024, Method: Composition-based stats. Identities = 37/220 (16%), Positives = 65/220 (29%), Gaps = 21/220 (9%) Query: 228 VASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAG 287 V + L L+D+ + N + I D F G E G I +K Sbjct: 244 VPADGFLPTLLDWCRKNDVVFIADEVQTGFARTG-AMFACEHEGIDPDLIV---TAKGIA 299 Query: 288 FTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRS 347 G+ L E++ S + G + IA A LA + + + + + Sbjct: 300 -GGLPLSAVTGRAEIMDSPHVSGL--------GGTYGGNPIACAAALATIETIESEGLVA 350 Query: 348 VNNYYKENRKILMDTLVSLGLKV--YGGVNAPYLWVHFKGSKSW---DVFNEILENTHII 402 ++ K + L + ++ G A K + D+ + H Sbjct: 351 RAQQIEKIMKDRLGRLQAEDDRIGDVRGRGAMIAMELVKAGTTEPDADLTKALCAGAHAA 410 Query: 403 TVPGSGFGPGGEEYLRI--SGFGRRDHIVEASKRLQNFFN 440 V G G +R D + E L+ Sbjct: 411 GVIVLSCGTYG-NVVRFLPPLSIGDDLLNEGLDVLEEVLR 449 >1DJ9-A nrPDB Length = 384 Score = 36.3 bits (82), Expect = 0.029, Method: Composition-based stats. Identities = 22/133 (16%), Positives = 42/133 (31%), Gaps = 11/133 (8%) Query: 234 LHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRL 293 L ++ + + ++ D A+ + R + + + V +F K G +G + Sbjct: 187 LAEIQQVTQQHNGWLMVDDAHGTGVIGEQGRGSCWLQKVKPELLVV-TFGKGFGVSGAAV 245 Query: 294 GWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQA--GGLACLSSGGLKEIRSVNNY 351 L S + F R + S + AQA LA + S R Sbjct: 246 --------LCSSTVADYLLQFARHLIYSTSMPPAQAQALRASLAVIRSDEGDARREKLAA 297 Query: 352 YKENRKILMDTLV 364 + + L Sbjct: 298 LITRFRAGVQDLP 310 >6CBN-A nrPDB Length = 438 Score = 36.3 bits (82), Expect = 0.030, Method: Composition-based stats. Identities = 32/245 (13%), Positives = 64/245 (26%), Gaps = 33/245 (13%) Query: 200 NNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIE 259 + +L P SP++ S +L G +++ D Sbjct: 178 DLGLLRELLRAPERVAAVVVSPDH---MHLSPGWYRELRRLCSAAGVVLVADEVKVGLRY 234 Query: 260 DGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVT 319 S E+ + +K G + ++ + Sbjct: 235 AP-GLSTAELLAPDVWVV-----AK---------GMANGHAVSAVGGSRRLLKPLKEVSF 279 Query: 320 TSFNGASNIAQAGGLACLSSGGLKE---IRSVNNYYKENRKILMDTLVSLGLKVYGGVNA 376 TSF + +A A + G + + + + + RK L D + + + G Sbjct: 280 TSFFEPTILAAADAALARVATGEPQRAVREAGDRFLRHARKALDDASLPVEI---AGDGT 336 Query: 377 PYLWVHFKGSKSWDVFNEILENTHIITVPGSGFGPGGEEYLRISGFGRRDHIVEASKRLQ 436 + +V E LE G + +S + EA +R Sbjct: 337 FFQFVP---------ATEELEEALYGAANAEGLLFYAGDNQGVSAAFDEAVLGEAERRFA 387 Query: 437 NFFNT 441 Sbjct: 388 RVCER 392 >4PPM-A nrPDB Length = 861 Score = 35.9 bits (81), Expect = 0.033, Method: Composition-based stats. Identities = 48/376 (12%), Positives = 105/376 (27%), Gaps = 52/376 (13%) Query: 85 PEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQS 144 P+ + + + N + + + Y +AE R VF S+ Sbjct: 451 PQPVVNALKN--YLDAQGPNFIQY---ISIPEQTAKLAEVLCRLAPGNMGRVFFSNSGTE 505 Query: 145 DISRLQLLLGS---NVTIAVQDPTFPA-YIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPN 200 + + + IA ++ + + I G+ H T +V +P G + Sbjct: 506 AVEAAMKIAKASTGKPGIAYLRNSYHGKTLGALSITGRDKHRRYFTPLLDAMVEVPFG-D 564 Query: 201 NSFFPDLAMTPRTDVIFFCSPNNPTGYV--ASRKQLHQLVDFAKTNGSIIIFDSAYAAFI 258 + + + P G V L + + G +++ D Sbjct: 565 LAALREALNREDVGALMI-EPIQGEGGVHIPPAGYLQAVQQLCRETGVLLMVDEVQTGLG 623 Query: 259 EDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIV 318 G E G + + SK + +G ++ +L + + + F Sbjct: 624 RTGK-LFACEWDGIEPDVLML---SKSLSGGLIPIGATLCRADL-WQKAYGTADRFLVHS 678 Query: 319 TT--SFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLKVYGGVNA 376 +T N AS +A + L+ + + Y+K+ + + G Sbjct: 679 STYGGGNLASVVALSALREILAQDLVGHAERMGAYFKQ--ALSEIAARYPFVSEVRGRGL 736 Query: 377 PY------LWVHFKGSKSWDVFNEILENTHIITVPGSG-----FGPGGEEYLRISGFGRR 425 + + + + + PG F P + Sbjct: 737 MLGIQFDQAFTGAVNASAREFATRL---------PGDWHTTWKFLPDPV----------Q 777 Query: 426 DHIVEASKRLQNFFNT 441 H+ A R++ Sbjct: 778 AHLRAAMDRMEQALGE 793 Score = 30.1 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 17/135 (12%), Positives = 41/135 (30%), Gaps = 13/135 (9%) Query: 225 TGYVASRKQLHQLVDFAKTNGSIIIFDSAY--AAFIEDGSPRSIYEIPGAREVAIEVSSF 282 G + +++ ++ + A+ +G AY A++ E +S+ + I Sbjct: 314 LGRYLAPEKVLEIGEIAERHGFF-----AYPLASYGERIDRQSVTNLKRYYHHDIYAGE- 367 Query: 283 SKFAGFTGVRLGWSII-----PDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACL 337 S A RL + P + + + + N+ ++ L Sbjct: 368 SADAALPASRLAFIDAVIAQTPAREDTLDRYHQYINPMMVDFLKLQRCDNVFRSAAGTQL 427 Query: 338 SSGGLKEIRSVNNYY 352 + + Y Sbjct: 428 YDDAGEAFLDMVAGY 442 >4ADC-A nrPDB Length = 406 Score = 35.9 bits (81), Expect = 0.042, Method: Composition-based stats. Identities = 30/221 (13%), Positives = 64/221 (28%), Gaps = 35/221 (15%) Query: 226 GYVA-SRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSK 284 G V S L L + + +++IFD G + V ++ + +K Sbjct: 197 GVVPASNAFLQGLRELCNRHNALLIFDEVQTGVGRTGELYA----YMHYGVTPDLLTTAK 252 Query: 285 FAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLA-CLSSGGLK 343 G G +G + +E R++T +G + A L Sbjct: 253 ALG-GGFPVGALLATEE------------CARVMTVGTHGTTYGGNPLASAVAGKVLELI 299 Query: 344 EIRSVNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFKGSK-------SWDVFNEIL 396 + N K+ ++ L ++ + L+ +G + D + Sbjct: 300 NTPEMLNGVKQRHDWFVERLNTI-------NHRYGLFSEVRGLGLLIGCVLNADYAGQAK 352 Query: 397 ENTHIITVPGSGFGPGGEEYLRISGF--GRRDHIVEASKRL 435 + + G G +R + + + R Sbjct: 353 QISQEAAKAGVMVLIAGGNVVRFAPALNVSEEEVTTGLDRF 393 >3MAF-B nrPDB Length = 518 Score = 35.1 bits (79), Expect = 0.068, Method: Composition-based stats. Identities = 43/243 (17%), Positives = 79/243 (32%), Gaps = 23/243 (9%) Query: 137 FVSDGAQSDISRLQLLLG--SNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVY 194 V+ G + + T + P ++ V + F +K +Y + Sbjct: 168 TVTSGGTESLLLAMKTYRDWARATKGITAP------EAVVPVSAHAAF-DKAAQYFGIKL 220 Query: 195 MPCGPNNSFFPDLA-----MTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIII 249 + + + D+A +TP T V+ +P P G V + ++ A +G Sbjct: 221 VRTPLDADYRADVAAMREAITPNTVVVAGSAPGYPHGVV---DPIPEIAALAAEHGIGCH 277 Query: 250 FDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFS----KF-AGFTGVRLGWSIIPDELLY 304 D+ FI + R Y +P V+S S K+ G G + PD L Y Sbjct: 278 VDACLGGFILPWAERLGYPVPPFDFRLEGVTSVSADTHKYGYGAKGTSVILYRRPDLLHY 337 Query: 305 SNGFPIINDFHRIVTTSFNGA-SNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILMDTL 363 + +F G+ A A + S G + + L + Sbjct: 338 QYFIAADWPGGLYFSPTFAGSRPGALSATAWAAMLSLGEEGYLDATRRILQAADRLKAGV 397 Query: 364 VSL 366 ++ Sbjct: 398 RAI 400 >4GSA-A nrPDB Length = 432 Score = 35.1 bits (79), Expect = 0.069, Method: Composition-based stats. Identities = 56/366 (15%), Positives = 100/366 (27%), Gaps = 56/366 (15%) Query: 109 GLEQGNK-TLRKAIAETFYRDLHVKSNEVFVSDGAQS--DISRLQLLLGSNVTIAVQDPT 165 G G L +AE + FV+ G ++ + RL I + Sbjct: 89 GTSFGAPCALENVLAEMVNDAVPSIEMVRFVNSGTEACMAVLRLMRAYTGRDKIIKFEGC 148 Query: 166 FPAYIDS-SVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNP 224 + + D V G + + DL +F +P Sbjct: 149 YHGHADMFLVKAGSGVATLGLPSSPGVPKKTTANTLTTPYNDLEA---VKALFAENPGEI 205 Query: 225 TGY------------VASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGA 272 G V L L + + ++++FD F + + Sbjct: 206 AGVILEPIVGNSGFIVPDAGFLEGLREITLEHDALLVFDEVMTGF-----RIAYGGVQEK 260 Query: 273 REVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAG 332 V ++++ K G G+ +G E++ ++ T S N + A Sbjct: 261 FGVTPDLTTLGKIIG-GGLPVGAYGGKREIMQLVAPAG--PMYQAGTLSGNPLAMTAGIK 317 Query: 333 GLACLSSGGLKEIRSVNNYYKENRKILMDTLVSL---------GLKVYGGVNAP------ 377 L L G E Y + K L D L+++ G +V G Sbjct: 318 TLELLRQPGTYE------YLDQITKRLSDGLLAIAQETGHAACGGQVSGMFGFFFTEGPV 371 Query: 378 --YLWVHFKGSKSWDVFNEILENTHIITVPGSGFGPGGEEYLRISGFGRRDHIVEASKRL 435 Y + + F+ + I P S F G S + I Sbjct: 372 HNYEDAKKSDLQKFSRFHRGMLEQGIYLAP-SQFEAGFT-----SLAHTEEDIDATLAAA 425 Query: 436 QNFFNT 441 + + Sbjct: 426 RTVMSA 431 >4OBV-D nrPDB Length = 490 Score = 35.1 bits (79), Expect = 0.072, Method: Composition-based stats. Identities = 18/148 (12%), Positives = 44/148 (29%), Gaps = 15/148 (10%) Query: 119 KAIAETFYRDLHVKSNE--VFVSDGAQSDISRLQLLLGSN--VTIAVQDPTFPAYIDSSV 174 + + + + + N VFVS G+ ++I+ L + + + S Sbjct: 135 QEVLKWLAKQVGFTENPGGVFVSGGSMANITALTAARDNKLTDINLHLGTAYISDQTHSS 194 Query: 175 IIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTD-----VIFFCSP--NNPTGY 227 + + + + ++ + A+ + + N TG Sbjct: 195 VAKGLRIIGITDSRIRRIPTNSHFQMDTTKLEEAIETDKKSGYIPFVVIGTAGTTN-TGS 253 Query: 228 VASRKQLHQLVDFAKTNGSIIIFDSAYA 255 + L ++ K + D AY Sbjct: 254 I---DPLTEISALCKKHDMWFHIDGAYG 278 >2JJG-A nrPDB Length = 449 Score = 35.1 bits (79), Expect = 0.073, Method: Composition-based stats. Identities = 24/218 (11%), Positives = 59/218 (27%), Gaps = 26/218 (11%) Query: 229 ASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFA-- 286 + + + +++IFD G+ + ++ A ++ +F K Sbjct: 249 FRPEFFAAMRELCDEFDALLIFDEVQTGCGLTGTAWAYQQLDVAPDIV----AFGKKTQV 304 Query: 287 --GFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKE 344 G R+ + + N F + + + + + + G + Sbjct: 305 CGVMAGRRV-------DEVADNVFAVPSRLNSTWGGNLTDMVRARRILEVIEA-EGLFER 356 Query: 345 IRSVNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSWDVFNEILENTHIITV 404 Y + L ++ L G + + D L +I + Sbjct: 357 AVQHGKYLRARLDELAADFPAVVLDP-RGRGLMCAF-SLPTTADRDELIRQLWQRAVIVL 414 Query: 405 PGSGFGPGGEEYLRIS--GFGRRDHIVEASKRLQNFFN 440 P G + +R I A +++ Sbjct: 415 PA------GADTVRFRPPLTVSTAEIDAAIAAVRSALP 446 >1VJO-A nrPDB Length = 393 Score = 34.7 bits (78), Expect = 0.077, Method: Composition-based stats. Identities = 38/336 (11%), Positives = 91/336 (27%), Gaps = 64/336 (19%) Query: 137 FVSDGAQSDISRLQLLLGSNVTIAVQDPTF--PAYIDSSVIIGQTGHFHE-KTKKYQNVV 193 G + + + + + + + +D + G + ++ Sbjct: 90 VSGTGTAAMEATIANAVEPGDVVLIGVAGYFGNRLVDMAGRYGADVRTISKPWGEVFSLE 149 Query: 194 YMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSA 253 + T R ++ TG R+ L + + + G++++ D+ Sbjct: 150 ELRTALE---------THRPAILALVHAETSTGA---RQPLEGVGELCREFGTLLLVDTV 197 Query: 254 YAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIIND 313 S+ +P I + ++ ++ + G P ++ I Sbjct: 198 ----------TSLGGVP------IFLDAWGVDLAYSCSQKGLGCSPGASPFTMSSRAIEK 241 Query: 314 FHRIVTTSFN--------------------GASNIAQAGGLACLSSGGLKEIRSVNNYYK 353 R T N A L + + + ++ Sbjct: 242 LQRRRTKVANWYLDMNLLGKYWGSERVYHHTAPINLYYALREALRLIAQEGLANCWQRHQ 301 Query: 354 ENRKILMDTLVSLGL------KVYGGVNAPYLWVHFKGSKSWDVFNEILENTHIITVPGS 407 +N + L + L +GL + G V +L +I G Sbjct: 302 KNVEYLWERLEDIGLSLHVEKEYRLPTLTTVCIPD--GVDGKAVARRLLNEHNIEV--GG 357 Query: 408 GFGPGGEEYLRISGFG---RRDHIVEASKRLQNFFN 440 G G + R+ G R++ + + L+ Sbjct: 358 GLGELAGKVWRVGLMGFNSRKESVDQLIPALEQVLR 393 >3N5M-A nrPDB Length = 452 Score = 34.7 bits (78), Expect = 0.088, Method: Composition-based stats. Identities = 19/205 (9%), Positives = 58/205 (28%), Gaps = 18/205 (8%) Query: 166 FPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNP- 224 + + + + + + +N+ + C ++ P Sbjct: 169 YEPFASGFLHVTPPDCYRMPGIERENIYDVECVKEVDRVMTWELSETIAAFIME----PI 224 Query: 225 -TG---YVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVS 280 TG +A + + + + + +G+++I D F G +V ++ Sbjct: 225 ITGGGILMAPQDYMKAVHETCQKHGALLISDEVICGFGRTGKAFGFM----NYDVKPDII 280 Query: 281 SFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSG 340 + +K G+ + + + + A L + Sbjct: 281 TMAK-----GITSAYLPLSATAVKREIYEAFKGKGEYEFFRHINTFGGNPAACALALKNL 335 Query: 341 GLKEIRSVNNYYKENRKILMDTLVS 365 + E ++ + +L++ L Sbjct: 336 EIIENENLIERSAQMGSLLLEQLKE 360 >4UHN-A nrPDB Length = 468 Score = 34.3 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 23/138 (16%), Positives = 47/138 (34%), Gaps = 5/138 (3%) Query: 228 VASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAG 287 V + L +L + N ++IFD AF G V ++ + +K Sbjct: 256 VPPKGYLQRLREICDANDILLIFDEVITAFGRMGKATGA----EYFGVTPDIMNVAKQVT 311 Query: 288 FTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFN-GASNIAQAGGLACLSSGGLKEIR 346 V +G I E+ + + ++ + A +A A G+A L + + Sbjct: 312 NGAVPMGAVIASSEIYDTFMNQNLPEYAVEFGHGYTYSAHPVACAAGIAALDLLQKENLI 371 Query: 347 SVNNYYKENRKILMDTLV 364 + + + + L Sbjct: 372 QQSAELAPHFEKALHGLK 389 >5VIU-A nrPDB Length = 419 Score = 34.3 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 26/218 (11%), Positives = 61/218 (27%), Gaps = 24/218 (11%) Query: 228 VASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAG 287 V + L Q + K + + I D G + + ++ I K Sbjct: 217 VPNEGFLKQSSELCKKHNVLFIADEVQTGIARTGKLIACHHEDVQPDILI----LGKALS 272 Query: 288 FTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRS 347 G +L +N + S G + +A A +A L +++ Sbjct: 273 ------GGMYPVSAVLANNNIMDV--IKPGQHGSTFGGNPLACAVAMAALDVVQDEKLSE 324 Query: 348 VNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWV----HFKGSKSWDVFNEILENTHIIT 403 + ++ L+ + L S + L+ ++ Sbjct: 325 RAEKLGNLFRSEIEKLIEKTDLITKVRGKGLLNAILINDTPDSSTAWNLCLALKENGLLA 384 Query: 404 VPGSGFGPGGEEYLRIS--GFGRRDHIVEASKRLQNFF 439 P G +R++ + +++ K ++ Sbjct: 385 KPTHG------NIIRLAPPLVITEEQLLDCVKIIEKTI 416 >4JF0-A nrPDB Length = 422 Score = 34.3 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 34/225 (15%), Positives = 62/225 (27%), Gaps = 34/225 (15%) Query: 227 YVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFA 286 A+ + L L D + ++++FD G V ++ + +K Sbjct: 217 QAATPEFLKGLRDLCDEHQALLVFDEVQCGMGRTGD----LFAYMHYGVTPDILTSAKAL 272 Query: 287 GFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIR 346 G G + + E I + FH S G + +A A A Sbjct: 273 G-GGFPVSAMLTTQE--------IASAFHVGSHGSTYGGNPLACAVAGATFDIINT---P 320 Query: 347 SVNNYYKENRKILMDTLVSLG-----LKVYGGVN---APYLWVHFKGSKSWDVFNEILEN 398 V R+ + L ++ G+ L +KG F Sbjct: 321 EVLQGIHTKRQQFVQHLQAIDEQFDIFSDIRGMGLLIGAELKPKYKGRARD--FLYAGAE 378 Query: 399 THIITVPGSGFGPGGEEYLRI--SGFGRRDHIVEASKRLQNFFNT 441 ++ + G + +R S I E +R Sbjct: 379 AGVMVLNA------GADVMRFAPSLVVEEADIHEGMQRFAQAVGK 417 >5KR3-A nrPDB Length = 479 Score = 33.9 bits (76), Expect = 0.13, Method: Composition-based stats. Identities = 44/326 (13%), Positives = 87/326 (26%), Gaps = 45/326 (13%) Query: 62 EHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAI 121 E+I+ + +++G G T ++ + A L+ Y G+ + + + I Sbjct: 70 EYIDAFAGLYCVNIGYGRT------EVADAIYEQAKQLAYYHTYVGHSTDAIIELSSRII 123 Query: 122 AET--------FYRDLHVKSNE-----------VFVSDGAQSDISRLQLLLGSNVTIAVQ 162 + +Y +NE V + ISR + GS + Sbjct: 124 RDWAPAGMKKVYYGMSGSDANETQIKLVWYYNNVLGRPNKKKIISRERGYHGSGIVTGSL 183 Query: 163 D--PTFPAYIDS----SVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVI 216 P+F + D + + C T Sbjct: 184 TGLPSFHQHFDLPIDRVKHTVCPHWYRAPAGMSEAQFVAYCVEELEKLIAREGAD-TIAA 242 Query: 217 FFCSPNNPTGYVASRKQ--LHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGARE 274 F P TG + Q + + + ++I D F GS + Sbjct: 243 FIAEPVMGTGGIIPPPQGYWEAIQAVLRKHDILLIADEVVCGFGRLGSKMGSQHYGIKPD 302 Query: 275 VAIEVSSFSKFAG-FTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGG 333 + + +GV +G E ++ + + I A Sbjct: 303 LITVAKGLTSAYAPLSGVIVG------EKVWDVIEKGSQEHGPMGHGWTYSGHPICAAAA 356 Query: 334 LACLSSGGLKEIRSVN----NYYKEN 355 LA L + + Y ++ Sbjct: 357 LANLDILERENLTGNAADVGAYLQQR 382 >2BHU-A nrPDB Length = 602 Score = 33.9 bits (76), Expect = 0.14, Method: Composition-based stats. Identities = 18/68 (26%), Positives = 22/68 (32%), Gaps = 9/68 (13%) Query: 221 PNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVS 280 P P G + L LVD A G + D Y F G+ S Y + Sbjct: 185 PYAPYGR---PEDLMALVDAAHRLGLGVFLDVVYNHFGPSGNYLSSYAPSYFTDR----- 236 Query: 281 SFSKFAGF 288 FS G Sbjct: 237 -FSSAWGM 243 >5KR5-A nrPDB Length = 479 Score = 33.9 bits (76), Expect = 0.15, Method: Composition-based stats. Identities = 27/202 (13%), Positives = 54/202 (26%), Gaps = 16/202 (7%) Query: 164 PTFPAYIDSS---VIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCS 220 P+F + D V H++ ++ T F Sbjct: 187 PSFHQHFDLPIDRVKHTVCPHWYNAPPGMSEAQFVAYCVEELEKLIAREGADTIAAFIAE 246 Query: 221 PNNPTGYVASRKQ--LHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIE 278 P TG + Q + + + ++I D F GS ++ E G + I Sbjct: 247 PVMGTGGIVPPPQGYWEAIQAVLRKHDILLIADEVVCGFGRLGS-KTGSEHYGIKPDLIT 305 Query: 279 V-SSFSKFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACL 337 V + ++I E ++ + + + A LA L Sbjct: 306 VAKGLTSAYAPLS-----AVIVSEKVWDVIEKGSREHGVMGHGWTYSGHPVCAAAALANL 360 Query: 338 SSGGLKEIRSVN----NYYKEN 355 + + Y ++ Sbjct: 361 DILERENLTGNAADVGAYLQQR 382 >3I4J-A nrPDB Length = 430 Score = 33.6 bits (75), Expect = 0.17, Method: Composition-based stats. Identities = 23/144 (15%), Positives = 46/144 (31%), Gaps = 12/144 (8%) Query: 228 VASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAG 287 + ++ D G I I D + GSP ++ G + Sbjct: 208 APAPGYYERVRDICDEAGIIFIADEVMSGMGRCGSPLALSRWSGVTPDIAVLG------- 260 Query: 288 FTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASN-IAQAGGLACLSSGGLKEIR 346 G+ G++ + L + + F A + ++ A GL+ L +++ Sbjct: 261 -KGLAAGYAPLAGLLAAPQVYETVMGGSGAFMHGFTYAGHPVSVAAGLSVLDIVEREDLT 319 Query: 347 SVNNYYKENRKILMDTLVSLGLKV 370 KE L+ L +L + Sbjct: 320 GAA---KERGAQLLAGLQALQARF 340 >4P3M-A nrPDB Length = 429 Score = 33.6 bits (75), Expect = 0.19, Method: Composition-based stats. Identities = 44/280 (15%), Positives = 78/280 (27%), Gaps = 38/280 (13%) Query: 104 GYRGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQD 163 G R YG + E V G+Q++ + Q L TI Sbjct: 61 GKRYYGGCEYVDVAESLAIERAKSLFGADYANVQPHSGSQANAAVYQALCAPGDTIL--- 117 Query: 164 PTFPAYIDSSVIIGQ---TGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDV----- 215 S+ G G + K N V P D A R V Sbjct: 118 -------GMSLAHGGHLTHGSHVSFSGKMYNAVQYGITPETGIL-DYAEIERLAVEHKPT 169 Query: 216 IFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAY-AAFIEDGSPRSIYEIPGARE 274 + + +G V + + A G+ + D A+ A + G + Sbjct: 170 MIIAGFSAYSGIV----DWAKFREIADKVGAYLFVDMAHVAGLVAAGLYPNPVPFAD--- 222 Query: 275 VAIEVSSFSKFAGFTGVRLGWSIIP-DELLYSNGFPIINDFHRIVTTSFNGASNIAQAGG 333 + ++ K G G R G + +E + + ++ A Sbjct: 223 --VVTTTTHKTLG--GPRGGLILAKANEAIEKKLNSAV-----FPGQQGGPLMHVIAAKA 273 Query: 334 LACLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLKVYGG 373 +A + N K ++ + ++ G K+ G Sbjct: 274 VAFKECAEPEFAVYQQQVLD-NAKAMVKSFLARGYKIVSG 312 >1SFF-A nrPDB Length = 426 Score = 33.6 bits (75), Expect = 0.21, Method: Composition-based stats. Identities = 19/150 (12%), Positives = 48/150 (32%), Gaps = 15/150 (10%) Query: 230 SRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFT 289 S + +L +G ++I D + G+ ++ ++ A ++ +F+K Sbjct: 218 SPAFMQRLRALCDEHGIMLIADEVQSGAGRTGTLFAMEQMGVAPDLT----TFAK--SIA 271 Query: 290 GVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVN 349 G G+ + + +++ + IA L L + + Sbjct: 272 G---GFPLA----GVTGRAEVMDAVAPGGLGGTYAGNPIACVAALEVLKVFEQENLLQKA 324 Query: 350 NYYKENRKILMDTLVS--LGLKVYGGVNAP 377 N + K + + + G+ A Sbjct: 325 NDLGQKLKDGLLAIAEKHPEIGDVRGLGAM 354 >3RI6-A nrPDB Length = 430 Score = 33.6 bits (75), Expect = 0.21, Method: Composition-based stats. Identities = 17/113 (15%), Positives = 34/113 (30%), Gaps = 13/113 (11%) Query: 139 SDGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCG 198 G + + + L + ++ D + G T +KT + Sbjct: 104 GSGMAAISTAILTLARAGDSVVTTD----------RLFGHTLSLFQKTLPSFGIEVRFVD 153 Query: 199 PNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFD 251 +S + A T ++F + +NP L L G ++ D Sbjct: 154 VMDSLAVEHACDETTKLLFLETISNPQ---LQVADLEALSKVVHAKGIPLVVD 203 >5LH9-A nrPDB Length = 458 Score = 33.2 bits (74), Expect = 0.22, Method: Composition-based stats. Identities = 15/80 (18%), Positives = 24/80 (30%), Gaps = 26/80 (32%) Query: 228 VASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAG 287 V +L + +G ++I D V+ F + Sbjct: 241 VPPADYWPRLREVCDRHGILLIADEV-------------------------VTGFGRSGC 275 Query: 288 FTGVRLGWSIIPDELLYSNG 307 G R GW + PD L + G Sbjct: 276 MLGSR-GWGVAPDILCLAKG 294 >6GIO-D nrPDB Length = 439 Score = 33.2 bits (74), Expect = 0.25, Method: Composition-based stats. Identities = 6/26 (23%), Positives = 11/26 (42%) Query: 228 VASRKQLHQLVDFAKTNGSIIIFDSA 253 V L L D + +G +++ D Sbjct: 215 VPPPAFLEALQDRCRKHGILVVVDEV 240 >4E3Q-A nrPDB Length = 473 Score = 32.8 bits (73), Expect = 0.29, Method: Composition-based stats. Identities = 19/159 (11%), Positives = 37/159 (23%), Gaps = 10/159 (6%) Query: 226 GYVASRK--QLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFS 283 G V ++ + +I D F G+ + I S Sbjct: 249 GGVIPPAKGYFQAILPILRKYDIPVISDEVICGFGRTGNTWGCVTYDFTPDAIIS----S 304 Query: 284 KFAGFTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLK 343 K +G ++I L I + A L + + Sbjct: 305 KNLTAGFFPMG-AVILGPELSKRLETAIEAIEEFPHGFTASGHPVGCAIALKAIDVVMNE 363 Query: 344 EIRSVNNYYKEN-RKILMDTLVSLGLKVYGGVNAPYLWV 381 + + L + Y G+ ++W Sbjct: 364 GLAENVRRLAPRFEERLKHIAERPNIGEYRGIG--FMWA 400 >3NNK-A nrPDB Length = 411 Score = 32.8 bits (73), Expect = 0.33, Method: Composition-based stats. Identities = 52/357 (14%), Positives = 109/357 (30%), Gaps = 54/357 (15%) Query: 120 AIAETFYRDLHVKSNEVFVSDG-AQSDISR-LQLLLGSNVTIAVQDPTF----PAYIDSS 173 + + ++ + DG +++ I L + + V P F + + Sbjct: 50 EVMALYRGVFRTENRWTMLVDGTSRAGIEAILVSAIRPGDKVLV--PVFGRFGHLLCEIA 107 Query: 174 VIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQ 233 H E P L +T + D T + Sbjct: 108 RRCRAEVHTIEVPWGEVFTPDQVEDAVKRIRPRLLLTVQGD----------TSTTM-LQP 156 Query: 234 LHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRS---IYEIPGAREVAIEVSSFSKFAGFT- 289 L +L + + ++ D A A+ + + + + + S + T Sbjct: 157 LAELGEICRRYDALFYTD-ATASLGGNPLETDVWGLDAVSAGMQKC--LGGPSGTSPITL 213 Query: 290 ----------------GVRL-GWSIIPDELLYSNGFPI--INDFHRIVTTSFNGASNIAQ 330 G+R +E++YSN F + + D+ + + + A Sbjct: 214 SARMEEAIRRRKCVEEGIRTDAHRDGDEEMIYSNYFDLGMVMDYWGPERLNHHTEATTAL 273 Query: 331 AGGLACLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLKVY---GGVNAPYLWVHFKGSK 387 G C + + +K + L+ + ++GL+ + L V Sbjct: 274 FGARECARLILQEGLDYGIARHKLHGDALVKGIQAMGLETFGDLKHKMNNVLGVVIPQGI 333 Query: 388 SWDVFNEI-LENTHIITVPGSGFGPGGEEYLRI---SGFGRRDHIVEASKRLQNFFN 440 + D ++ LE+ I G+ FGP + RI R+D ++ L+ N Sbjct: 334 NGDQARKLMLEDFGIEI--GTSFGPLHGKVWRIGTMGYNARKDCVMTTLSALEAVLN 388 >4BQ0-A nrPDB Length = 448 Score = 32.8 bits (73), Expect = 0.34, Method: Composition-based stats. Identities = 23/138 (16%), Positives = 46/138 (33%), Gaps = 5/138 (3%) Query: 228 VASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAG 287 V L +L + + ++IFD AF G+ V ++ + +K Sbjct: 236 VPPVGYLQRLREICDQHNILLIFDEVITAFGRLGTYSGA----EYFGVTPDLMNVAKQVT 291 Query: 288 FTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFN-GASNIAQAGGLACLSSGGLKEIR 346 V +G I E+ + + + + + A +A A GLA L + Sbjct: 292 NGAVPMGAVIASSEIYDTFMNQALPEHAVEFSHGYTYSAHPVACAAGLAALDILARDNLV 351 Query: 347 SVNNYYKENRKILMDTLV 364 + + + + L Sbjct: 352 QQSAELAPHFEKGLHGLQ 369 >5EAV-A nrPDB Length = 441 Score = 32.4 bits (72), Expect = 0.39, Method: Composition-based stats. Identities = 36/292 (12%), Positives = 84/292 (28%), Gaps = 36/292 (12%) Query: 86 EQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSD 145 ++ + + A L+ R +G + R +AE F D + ++ GA++ Sbjct: 89 PRVIAALCRQAERLTL--TLRAFGNDVTGPACR-FMAEMFGYDR-----VLLMNTGAEAG 140 Query: 146 ISRLQLLLG----------SNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYM 195 S L++ + + + + + ++ T + + + Sbjct: 141 ESALKIARKWAYEVKEIPPDSAKVILCNNNYWGRTITACSSSTTFDCYNNFGPFTPGFEL 200 Query: 196 PCGPNNSFFPDLAMTPRTDVIFFCSPNNPTG--YVASRKQLHQLVDFAKTNGSIIIFDSA 253 + + P F P G V L + + ++ ++I D Sbjct: 201 IDYDDVGALEEALKDPNVAAFFV-EPIQGEGGVNVPKPGYLKRAHELCRSKNVLLIVDEI 259 Query: 254 YAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPIIND 313 G + ++ + S S + G + D Sbjct: 260 QTGLCRTGRLLAADHDEVHPDILLLGKSLS-------------AGVVPISAVMGRADVMD 306 Query: 314 FHRIVTT-SFNGASNIAQAGGLACLSSGGLKEIRSVNNYY-KENRKILMDTL 363 + T S G + +A A + L+ +++ + R L L Sbjct: 307 VLKPGTHGSTFGGNPLACAVAVEALTVLKDEKLADRAERLGAQFRDCLRREL 358 >3A74-A nrPDB Length = 493 Score = 32.0 bits (71), Expect = 0.62, Method: Composition-based stats. Identities = 19/120 (15%), Positives = 40/120 (33%), Gaps = 17/120 (14%) Query: 299 PDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKI 358 E + DF I+ + N ++I L + ++ + + E R++ Sbjct: 262 NPEFTMLELYEAYADFRDIMKLTENLIAHI----ATEVLGTTKIQYGEHLVDLTPEWRRL 317 Query: 359 -LMDTLVSLGLKVYGGVNAPYLWVHFKGSKSWDVFNEILENTHIITVPGSGFGPGGEEYL 417 ++D + Y+ V F S + E+ + + P FG E+ Sbjct: 318 HMVDAIKE------------YVGVDFWRQMSDEEARELAKEHGVEVAPHMTFGHIVNEFF 365 >4K5R-A nrPDB Length = 536 Score = 32.0 bits (71), Expect = 0.62, Method: Composition-based stats. Identities = 14/84 (16%), Positives = 25/84 (29%), Gaps = 11/84 (13%) Query: 52 LFPEINRRELEHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGY--G 109 L ++ R P +S+ G+ T P L +GY + Sbjct: 442 LLLDLAGRADLREATRPWSDRVSVVAGEATVEPP---------AQALLVRPDGYVAWAGS 492 Query: 110 LEQGNKTLRKAIAETFYRDLHVKS 133 LR ++A F + + Sbjct: 493 PAATADELRASLARWFGPPANREP 516 >2E8Y-A nrPDB Length = 718 Score = 31.6 bits (70), Expect = 0.78, Method: Composition-based stats. Identities = 12/69 (17%), Positives = 26/69 (37%), Gaps = 3/69 (4%) Query: 220 SPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEV 279 +P++P + +L Q+++ +G +I D + + + +PG E Sbjct: 307 NPHDPQ---TRKTELKQMINTLHQHGLRVILDVVFNHVYKRENSPFEKTVPGYFFRHDEC 363 Query: 280 SSFSKFAGF 288 S G Sbjct: 364 GKPSNGTGV 372 >3DOD-A nrPDB Length = 448 Score = 31.6 bits (70), Expect = 0.80, Method: Composition-based stats. Identities = 29/147 (19%), Positives = 48/147 (32%), Gaps = 16/147 (10%) Query: 228 VASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAG 287 V L + + T ++I D F G + V ++ + K G Sbjct: 228 VMPEGYLAGVRELCTTYDVLMIVDEVATGFGRTGKMFAC----EHENVQPDLMAAGK--G 281 Query: 288 FTGVRLGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIA-QAGGLACLSSGGLKEIR 346 TG G+ I + + D + + T F+G S Q G L + L E Sbjct: 282 ITG---GYLPIAVTFATEDIYKAFYDDYENLKTFFHGHSYTGNQLGCAVALENLALFESE 338 Query: 347 SVNNYYKENRKIL------MDTLVSLG 367 ++ E K L + L +G Sbjct: 339 NIVEQVAEKSKKLHFLLQDLHALPHVG 365 >2FQ6-A nrPDB Length = 415 Score = 31.3 bits (69), Expect = 0.92, Method: Composition-based stats. Identities = 17/133 (12%), Positives = 38/133 (28%), Gaps = 15/133 (11%) Query: 89 TSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISR 148 + + E + G + +L++A+ E + V GA + + Sbjct: 59 VEAKKHATRNRANGELFYGRRGTLTHFSLQQAMCELEGG-----AGCVLFPCGAAAVANS 113 Query: 149 LQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLA 208 + + + + + + + F K V P Sbjct: 114 ILAFIEQGDHVLMTNTAYEP----------SQDFCSKILSKLGVTTSWFDPLIGADIVKH 163 Query: 209 MTPRTDVIFFCSP 221 + P T ++F SP Sbjct: 164 LQPNTKIVFLESP 176 >5YKR-A nrPDB Length = 461 Score = 30.9 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 23/144 (15%), Positives = 44/144 (30%), Gaps = 11/144 (7%) Query: 121 IAETFYRDLHVKSNEVFVS-DGAQSDISRLQLLLGSNVTIAVQDPTFP-AYIDSSVIIGQ 178 + R + +V S A + RL +L + V + + + +S V Sbjct: 120 VGAELARRFGLPYWQVTTSATDANRFVLRLCRMLSGRDKVVVFNCNYHGSVDESQVEFDA 179 Query: 179 TGHFHEKTKKYQNVVYMPCGP-----NNSFFPDLAMTPRTDVIFFCSP--NNPTGYVASR 231 G + + N V N+ + A+ P N G V Sbjct: 180 AGRMVPRAGVHPNGVRHATTTRLVEFNDLDALEAALAHGDVAAVLTEPFMTN-VGMVPPA 238 Query: 232 KQLHQ-LVDFAKTNGSIIIFDSAY 254 + H L + + + +I D + Sbjct: 239 EGFHAGLRELTRRHDVALIIDETH 262 >5YZA-A nrPDB Length = 525 Score = 30.5 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 29/195 (14%), Positives = 65/195 (33%), Gaps = 21/195 (10%) Query: 36 TKLVRNVNLEKLKNNYLFPEINRRELEHIEKHPNVQLISLGTGDTTE---PIPEQITSHM 92 T L +++ +++ + I + +++ LG PE++ + Sbjct: 177 TDCQIYEVLSVIRDIGAIAQVHAENGDIIAEEQQ-RILDLGITGPEGHVLSRPEEVEAEA 235 Query: 93 SNFAHGLSTVEGYRGYGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSD------I 146 N A ++ Y + +K+ + IA+ + V + S G Sbjct: 236 VNRAITIANQTNCPLYITKVMSKSSAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNW 295 Query: 147 SRLQLLLGSNVTIAVQDPTFPAYIDSSVIIG---------QTGHFHEKTKKYQNVVYMPC 197 ++ + S DPT P +++S + G T + +K N +P Sbjct: 296 AKAAAFVTSPP--LSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPE 353 Query: 198 GPNNSFFPDLAMTPR 212 G N + + + Sbjct: 354 GTNGTEERMSVIWDK 368 >3A1D-A nrPDB Length = 287 Score = 30.5 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 22/114 (19%), Positives = 42/114 (36%), Gaps = 8/114 (7%) Query: 260 DGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRL---GWSIIPDELLYSNGFPIINDFHR 316 P + + A E IE+ K G + G + L+ G + N+ Sbjct: 74 SEHPIAEAIVKKALEHGIELGEPEKVEVIAGEGVVADGILVGNKRLMEDFGVAVSNEVEL 133 Query: 317 IVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLKV 370 + A + +G ++ I +V++ KE+ K + L +G+KV Sbjct: 134 ALEKLEREAKT-----AVIVARNGRVEGIIAVSDTLKESAKPAVQELKRMGIKV 182 >1O69-A nrPDB Length = 394 Score = 30.1 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 19/146 (13%), Positives = 44/146 (30%), Gaps = 21/146 (14%) Query: 114 NKTLRKAIAETFYR-DLHVKSNEVFVSDGAQSDISRL--QLLLGSNVTIAVQDPTFPAYI 170 L + + + KS + A + + + + + TF A + Sbjct: 27 IAPLGEFVNRFEQSVKDYSKSENALALNSATAALHLALRVAGVKQDDIVLASSFTFIASV 86 Query: 171 DSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTP---RTDVIFFCSPNNPTGY 227 + F + + Y V LA+ + + T Sbjct: 87 APICYLKAKPVFIDCDETYNIDV---------DLLKLAIKECEKKPKALIL------THL 131 Query: 228 VASRKQLHQLVDFAKTNGSIIIFDSA 253 + ++ ++V+ K N ++I D+A Sbjct: 132 YGNAAKMDEIVEICKENDIVLIEDAA 157 >5CM6-A nrPDB Length = 358 Score = 30.1 bits (66), Expect = 2.0, Method: Composition-based stats. Identities = 19/133 (14%), Positives = 46/133 (34%), Gaps = 9/133 (6%) Query: 291 VRLGWSIIPDELLYSNGFPIINDFHR-----IVTTSFNGASNIAQAGGLACLSSGGLKEI 345 RL + P+ ++ + + + +T + A+ A G+ G ++ Sbjct: 31 WRLAETWGPNFPIFGDASKNMAKMVKEMSDGRLTIRIDSANKHKSALGIFDFVKSGQYQM 90 Query: 346 RSVNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSWDVFNEILENTHIITVP 405 +YY + + ++ + Y W ++ G ++ E + I++ P Sbjct: 91 GHSASYYWKGKDFNTMFFTTVPFGMTAPEQ--YAWFYYGG--GMELMKETYDQYGILSFP 146 Query: 406 GSGFGPGGEEYLR 418 G G + R Sbjct: 147 GGNTGVQMGGWFR 159 >3O55-A nrPDB Length = 125 Score = 30.1 bits (66), Expect = 2.0, Method: Composition-based stats. Identities = 18/62 (29%), Positives = 25/62 (40%), Gaps = 6/62 (9%) Query: 62 EHIEKHPNVQLISLGTGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQGNKTLRKAI 121 E + +H L +L P PEQ M+ F H S Y E+ + LRK + Sbjct: 20 EELGRHSWAVLHTLAAYYPDLPTPEQQQD-MAQFIHLFSKF-----YPCEECAEDLRKRL 73 Query: 122 AE 123 A Sbjct: 74 AR 75 >3J09-A nrPDB Length = 723 Score = 30.1 bits (66), Expect = 2.1, Method: Composition-based stats. Identities = 22/114 (19%), Positives = 42/114 (36%), Gaps = 8/114 (7%) Query: 260 DGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRL---GWSIIPDELLYSNGFPIINDFHR 316 P + + A E IE+ K G + G + L+ G + N+ Sbjct: 446 SEHPIAEAIVKKALEHGIELGEPEKVEVIAGEGVVADGILVGNKRLMEDFGVAVSNEVEL 505 Query: 317 IVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLKV 370 + A + +G ++ I +V++ KE+ K + L +G+KV Sbjct: 506 ALEKLEREAKT-----AVIVARNGRVEGIIAVSDTLKESAKPAVQELKRMGIKV 554 >3J08-A nrPDB Length = 645 Score = 30.1 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 22/114 (19%), Positives = 42/114 (36%), Gaps = 8/114 (7%) Query: 260 DGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRL---GWSIIPDELLYSNGFPIINDFHR 316 P + + A E IE+ K G + G + L+ G + N+ Sbjct: 368 SEHPIAEAIVKKALEHGIELGEPEKVEVIAGEGVVADGILVGNKRLMEDFGVAVSNEVEL 427 Query: 317 IVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLKV 370 + A + +G ++ I +V++ KE+ K + L +G+KV Sbjct: 428 ALEKLEREAKT-----AVIVARNGRVEGIIAVSDTLKESAKPAVQELKRMGIKV 476 >5GKN-A nrPDB Length = 527 Score = 30.1 bits (66), Expect = 2.3, Method: Composition-based stats. Identities = 20/110 (18%), Positives = 39/110 (35%), Gaps = 8/110 (7%) Query: 6 FFSSASPLCSSPSKIPKASLDFEMKKLGGSTKLVRNVNLEKLKNNYLFPEIN---RRELE 62 +F+ L PS +P K L G + + +L NYL +N R + Sbjct: 325 YFAEVEQLAFDPSNMPPGIEPSPDKMLQGRLFAYPDTHRHRLGPNYLQIPVNCPYRARVA 384 Query: 63 HIEKHPNVQLISLGTGDT-----TEPIPEQITSHMSNFAHGLSTVEGYRG 107 + ++ + ++ G + PE S + + H V+ + Sbjct: 385 NYQRDGPMCMMDNQGGAPNYYPNSFSAPEHQPSALEHRTHFSGDVQRFNS 434 >2OCI-A nrPDB Length = 254 Score = 29.7 bits (65), Expect = 2.5, Method: Composition-based stats. Identities = 24/114 (21%), Positives = 40/114 (35%), Gaps = 13/114 (11%) Query: 75 LGTGDTTEPIPEQITSHMSNFAHGLSTVE--GYRGYGLEQGNKTLRKAIAETFYRDLHVK 132 LG+G+T + N L TV RGYG + R A+ F RD Sbjct: 33 LGSGETDFGP------QLKNLNKKLFTVVAWDPRGYGHSR--PPDRDFPADFFERDAKDA 84 Query: 133 SNEVFVSDGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKT 186 + + + + +T + +P+YI VI G + ++ Sbjct: 85 VDLMKALKFKKVSLLGWS---DGGITALIAAAKYPSYIHKMVIWGANAYVTDED 135 >5YSZ-A nrPDB Length = 360 Score = 29.7 bits (65), Expect = 3.0, Method: Composition-based stats. Identities = 9/59 (15%), Positives = 18/59 (30%), Gaps = 3/59 (5%) Query: 235 HQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFAGFTGVRL 293 L+ ++ Y F D ++ E+ V + S G +R+ Sbjct: 231 EALLAAGMEYDETLVS---YGDFTYDSGVAAMRELLDRAPDVDAVFAASDLMGLAALRV 286 >5VNX-A nrPDB Length = 393 Score = 29.7 bits (65), Expect = 3.1, Method: Composition-based stats. Identities = 23/135 (17%), Positives = 46/135 (34%), Gaps = 22/135 (16%) Query: 125 FYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHE 184 F ++ S G ++++ + L G + TI + ID + + T + Sbjct: 96 FAGGFSDAPRALYFSTGYMANLAAVTALAGKDATIFSDALNHASLIDGTRLSRATVQVYP 155 Query: 185 KTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRK----QLHQLVDF 240 + A T +T +I T V S L +L+ Sbjct: 156 HADTATLGALLE-----------ACTSQTKLIV-------TDTVFSMDGDIAPLAELLAL 197 Query: 241 AKTNGSIIIFDSAYA 255 A+ +G+ ++ D A+ Sbjct: 198 AERHGAWLVVDDAHG 212 >1EA9-C nrPDB Length = 583 Score = 29.7 bits (65), Expect = 3.1, Method: Composition-based stats. Identities = 6/27 (22%), Positives = 12/27 (44%) Query: 230 SRKQLHQLVDFAKTNGSIIIFDSAYAA 256 + L +LVD G ++ D+ + Sbjct: 217 DKDTLKKLVDLCHERGIRVLLDAVFNH 243 >2CH1-A nrPDB Length = 396 Score = 29.3 bits (64), Expect = 3.4, Method: Composition-based stats. Identities = 29/262 (11%), Positives = 69/262 (26%), Gaps = 55/262 (20%) Query: 137 FVSDGAQSDISRLQL-LLGSNVTIAVQ-DPTFPA-YIDSSVIIGQTGHFHEKTKKYQNVV 193 VS A + + + LL + + + + ++ S G E + Sbjct: 73 CVSGSAHAGMEAMLSNLLEEGDRVLIAVNGIWAERAVEMSERYGADVRTIEGPPDRPFSL 132 Query: 194 YMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSA 253 P +F ++ +G + + L + + ++I D+ Sbjct: 133 ETLARAIELHQP--------KCLFLTHGDSSSGLL---QPLEGVGQICHQHDCLLIVDAV 181 Query: 254 YAAFIEDGSPRSIYEIP---GAREVAIEVSSFSKFAGFTGVRLGWSIIPDELLYSNGFPI 310 S+ +P E+ + K G + S Sbjct: 182 ----------ASLCGVPFYMDKWEIDAVYTGAQKVLGAP-------PGITPISISPKALD 224 Query: 311 INDFHRIVTTSF---------------------NGASNIAQAGGLACLSSGGLKEIRSVN 349 + R + F + ++ L+ + + + Sbjct: 225 VIRNRRTKSKVFYWDLLLLGNYWGCYDEPKRYHHTVASNLIFALREALAQIAEEGLENQI 284 Query: 350 NYYKENRKILMDTLVSLGLKVY 371 E +IL + L +GL ++ Sbjct: 285 KRRIECAQILYEGLGKMGLDIF 306 >1CYG-A nrPDB Length = 680 Score = 29.3 bits (64), Expect = 3.6, Method: Composition-based stats. Identities = 11/60 (18%), Positives = 19/60 (31%), Gaps = 1/60 (1%) Query: 230 SRKQLHQLVDFAKTNGSIIIFDSAYAAFIE-DGSPRSIYEIPGAREVAIEVSSFSKFAGF 288 + +LVD A G +I D A + S E + + ++ A Sbjct: 110 TLSDFQRLVDAAHAKGIKVIIDFAPNHTSPASETNPSYMENGRLYDNGTLLGGYTNDANM 169 >6FK4-A nrPDB Length = 258 Score = 29.3 bits (64), Expect = 3.8, Method: Composition-based stats. Identities = 11/54 (20%), Positives = 20/54 (37%), Gaps = 5/54 (9%) Query: 356 RKILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSWDVFNEI-LENTHIITVPGSG 408 + +L L L+ A Y W ++G+ ++ L HI+ P Sbjct: 179 QNLLDLGLTDS-LRQVHPEGAFYTWFDYRGAM---FQRKLGLRIDHILVSPAMA 228 >3RSY-A nrPDB Length = 822 Score = 29.3 bits (64), Expect = 3.9, Method: Composition-based stats. Identities = 9/53 (16%), Positives = 18/53 (33%) Query: 293 LGWSIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEI 345 LG+ PDE +++ + + R A++ A L + Sbjct: 267 LGYVENPDEEKWADDAKQVVNKERAHALLSRFATSEQTDAAFAALKDYWTDLL 319 >1ULZ-A nrPDB Length = 451 Score = 29.3 bits (64), Expect = 3.9, Method: Composition-based stats. Identities = 18/113 (15%), Positives = 35/113 (30%), Gaps = 8/113 (7%) Query: 296 SIIPDELLYSNGFPIINDFHRIVTTSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKEN 355 +I + + + ++ + I T + N + LA G I + EN Sbjct: 30 AIYNEVESTARHVKLADEAYMIGTDPLDTYLNKQRIINLAL--EVGADAIHPGYGFLAEN 87 Query: 356 RKILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSWDVFNEILENTHIITVPGSG 408 + G+ G W + E+++ + VPGS Sbjct: 88 AEFA-KMCEEAGITFIGPH-----WKVIELMGDKARSKEVMKKAGVPVVPGSD 134 >3ROH-A nrPDB Length = 329 Score = 28.9 bits (63), Expect = 4.3, Method: Composition-based stats. Identities = 14/51 (27%), Positives = 18/51 (35%) Query: 178 QTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYV 228 Q + E K+ V N PD + +F SPN PTG Sbjct: 187 QKSYVSEVDKQNSKSVKWGVKANEFVTPDGKKSAHDRYLFVQSPNGPTGSA 237 >2ZUK-A nrPDB Length = 439 Score = 28.9 bits (63), Expect = 4.3, Method: Composition-based stats. Identities = 6/37 (16%), Positives = 12/37 (32%) Query: 228 VASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPR 264 V L + D + +G +++ D G Sbjct: 218 VPPDGFLRKFADICRAHGILVVCDEVKVGLARSGRLH 254 >1EHA-A nrPDB Length = 558 Score = 28.9 bits (63), Expect = 4.4, Method: Composition-based stats. Identities = 9/32 (28%), Positives = 14/32 (43%) Query: 231 RKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGS 262 + +LVD A G +I D Y +G+ Sbjct: 167 PEGFRKLVDEAHKKGLGVILDVVYNHVGPEGN 198 >3HXT-A nrPDB Length = 203 Score = 28.9 bits (63), Expect = 4.6, Method: Composition-based stats. Identities = 10/97 (10%), Positives = 34/97 (35%), Gaps = 4/97 (4%) Query: 325 ASNIAQAGGLACLSSGGLKEIRSVNNY--YKENRKILMDTLVSLGLKVYGGVNAPYLWVH 382 + A + L + +R+++ +++R + + + ++ Sbjct: 1 MAAAAVSSAKRSLRGELKQRLRAMSAEERLRQSRVLSQKVIAHSEYQKSKRISIFLSMQD 60 Query: 383 FKGSKSWDVFNEILENTHIITVPGSGFGPGGEEYLRI 419 ++ ++ +I + I +P F + +RI Sbjct: 61 --EIETEEIIKDIFQRGKICFIPRYRFQSNHMDMVRI 95 >2Z9W-A nrPDB Length = 392 Score = 28.9 bits (63), Expect = 4.9, Method: Composition-based stats. Identities = 23/183 (12%), Positives = 53/183 (28%), Gaps = 16/183 (8%) Query: 108 YGLEQGNKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRLQL-LLGSNVTIAVQDPTF 166 Y + + L + + + + + + + V + + L+ + + Sbjct: 34 YDYDPAFQLLYEKVVDKAQKAMRLSNKPVILHGEPVLGLEAAAASLISPDDVVLNLASG- 92 Query: 167 PAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTG 226 Y G + V Y + L P V+ C + P+G Sbjct: 93 -VY---GKGFGYWAKRYSPHLLEIEVPYNEAIDPQAVADMLKAHPEITVVSVCHHDTPSG 148 Query: 227 YVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKFA 286 + + + +G+ +I D+ S + P + I V+ +K Sbjct: 149 TI---NPIDAIGALVSAHGAYLIVDAV-------SSFGGMKTHPEDCKADIYVTGPNKCL 198 Query: 287 GFT 289 G Sbjct: 199 GAP 201 >2EJ2-A nrPDB Length = 308 Score = 28.6 bits (62), Expect = 5.7, Method: Composition-based stats. Identities = 35/201 (17%), Positives = 65/201 (32%), Gaps = 22/201 (10%) Query: 83 PIPEQITSHMSNFAH-GLSTVEGYRGYGLEQGNKTLR-KAIAETFYRDLHVKSNEVFVSD 140 P E TS +S+ H G S EG R Y +G R K + FY V E+ + Sbjct: 16 PQEEAKTSVLSHALHYGTSVFEGIRAYETAKGPAIFRLKEHVKRFYNSAKVLRMEIPFAP 75 Query: 141 GAQSDISRLQLLLGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKKYQNVVYMPCGPN 200 + L + + ++ YI +G V + Sbjct: 76 ---------EELEEAIKEVVRRNGYRSCYIRPLAWMGAKALGVNPLPNNPAEVMVAAWEW 126 Query: 201 NSFFPDLAMTPRTDVI---FFCSPNN--P----TGYVASRKQLHQLVDFAKTNGSIIIFD 251 ++ + A+ +I + P N P G L ++ A ++ D Sbjct: 127 GAYLGEEAVRKGARLITSSWARFPANVMPGKAKVGGNYVNSALAKMEAVAAGADEALLLD 186 Query: 252 SAYAAFIEDGSPRSIYEIPGA 272 ++ +GS +++ + Sbjct: 187 E--EGYVAEGSGENLFFVRDG 205 >4YPJ-A nrPDB Length = 810 Score = 28.6 bits (62), Expect = 6.4, Method: Composition-based stats. Identities = 8/73 (10%), Positives = 23/73 (31%), Gaps = 11/73 (15%) Query: 157 VTIAVQDPTFPAYIDSSVIIGQ-------TGHFHEKTKKYQNVVYMPCGPNNSFFPDLAM 209 I P + +Y S G F+ +++ + P+ ++ Sbjct: 560 DYIGEPTPYYNSYPAKSSYFGAVDTAGFPKDIFYYYQSQWKKEPMVHLLPHWNW----KE 615 Query: 210 TPRTDVIFFCSPN 222 + V+ + + + Sbjct: 616 GEKVRVLAYTNAS 628 >1WA5-C nrPDB Length = 960 Score = 28.6 bits (62), Expect = 6.6, Method: Composition-based stats. Identities = 6/40 (15%), Positives = 19/40 (47%) Query: 220 SPNNPTGYVASRKQLHQLVDFAKTNGSIIIFDSAYAAFIE 259 +P+NP + + + ++++ + ++ DS F+ Sbjct: 609 NPSNPRFTHYTFESIGAILNYTQRQNLPLLVDSMMPTFLT 648 >3U9T-A nrPDB Length = 655 Score = 28.6 bits (62), Expect = 6.9, Method: Composition-based stats. Identities = 11/56 (19%), Positives = 15/56 (26%), Gaps = 6/56 (10%) Query: 351 YYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSWDVFNEILENTHIITVPG 406 + EN GL G A S ++E + VPG Sbjct: 90 FLSENADFA-RACEEAGLLFLGPPAA-----AIDAMGSKSAAKALMEEAGVPLVPG 139 >5LBF-A nrPDB Length = 252 Score = 28.2 bits (61), Expect = 8.7, Method: Composition-based stats. Identities = 10/28 (35%), Positives = 12/28 (42%) Query: 201 NSFFPDLAMTPRTDVIFFCSPNNPTGYV 228 N + RT + C P N TGYV Sbjct: 110 NGKLGSYKIKERTKAMVACYPGNGTGYV 137 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.128 0.324 Lambda K H 0.267 0.0391 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,805,062 Number of Sequences: 36641 Number of extensions: 613010 Number of successful extensions: 2787 Number of sequences better than 10.0: 248 Number of HSP's better than 10.0 without gapping: 221 Number of HSP's successfully gapped in prelim test: 141 Number of HSP's that attempted gapping in prelim test: 2055 Number of HSP's gapped (non-prelim): 382 length of query: 456 length of database: 10,336,785 effective HSP length: 100 effective length of query: 356 effective length of database: 6,672,685 effective search space: 2375475860 effective search space used: 2375475860 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 61 (28.2 bits)