BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9ZPI5 (725 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2WTB-A nrPDB 1479 0.0 6IUM-B nrPDB 451 e-127 3ZWA-A nrPDB 350 1e-96 2D3T-A nrPDB 348 4e-96 5ZRV-A nrPDB 326 2e-89 4B3J-A nrPDB 259 3e-69 1ZCJ-A nrPDB 227 1e-59 3K6J-A nrPDB 221 1e-57 6ACQ-A nrPDB 181 1e-45 4KUG-A nrPDB 177 1e-44 3MOG-A nrPDB 173 2e-43 1F14-A nrPDB 161 9e-40 3HDH-A nrPDB 160 1e-39 6HRD-A nrPDB 157 1e-38 4PZE-A nrPDB 154 2e-37 4J0E-A nrPDB 148 7e-36 5Z7R-A nrPDB 137 2e-32 5ZAI-A nrPDB 134 2e-31 3H81-A nrPDB 124 2e-28 5JBW-A nrPDB 114 1e-25 3MOY-A nrPDB 114 2e-25 1ZEJ-A nrPDB 112 7e-25 5WYB-B nrPDB 111 1e-24 2DUB-A nrPDB 110 2e-24 4OM8-A nrPDB 101 1e-21 2HW5-A nrPDB 101 1e-21 4FZW-A nrPDB 98 1e-20 4DYD-A nrPDB 96 6e-20 2PPY-A nrPDB 96 8e-20 4JWV-A nrPDB 91 2e-18 3HIN-A nrPDB 86 5e-17 4JSB-A nrPDB 81 2e-15 4JCS-A nrPDB 80 2e-15 4IZC-A nrPDB 78 1e-14 2IEX-A nrPDB 75 8e-14 1NZY-B nrPDB 71 2e-12 5YLO-A nrPDB 70 2e-12 3T88-A nrPDB 70 4e-12 2VSU-C nrPDB 69 9e-12 4ZU2-A nrPDB 68 1e-11 3F3S-A nrPDB 68 1e-11 1EF9-A nrPDB 67 3e-11 1XX4-A nrPDB 66 4e-11 4EML-A nrPDB 66 4e-11 2UZF-A nrPDB 66 7e-11 2A81-A nrPDB 65 9e-11 3OME-A nrPDB 65 1e-10 3BPT-A nrPDB 62 7e-10 3ADO-A nrPDB 62 9e-10 3M6N-A nrPDB 61 1e-09 5KJP-A nrPDB 61 1e-09 3HE2-A nrPDB 60 2e-09 6OJM-A nrPDB 60 3e-09 5MRE-88 nrPDB 60 3e-09 2NP9-A nrPDB 55 1e-07 4Q1J-A nrPDB 55 2e-07 3T8B-A nrPDB 54 3e-07 5VE2-A nrPDB 52 7e-07 4JFC-A nrPDB 51 2e-06 4FZW-C nrPDB 50 4e-06 3LAO-A nrPDB 50 4e-06 4HDT-A nrPDB 49 8e-06 4HC8-A nrPDB 49 9e-06 3I47-A nrPDB 48 1e-05 3HP0-A nrPDB 47 2e-05 4J2U-A nrPDB 47 3e-05 4ZDC-A nrPDB 40 0.004 3JU1-A nrPDB 39 0.009 2BC1-A nrPDB 32 0.68 5X68-A nrPDB 32 0.71 5XVM-A nrPDB 32 0.82 5KVH-A nrPDB 30 3.3 3E6I-A nrPDB 30 4.5 2GVN-A nrPDB 29 7.9 5CWV-A nrPDB 29 8.0 5FA5-A nrPDB 29 9.2 >2WTB-A nrPDB Length = 725 Score = 1479 bits (3828), Expect = 0.0, Method: Compositional matrix adjust. Identities = 725/725 (100%), Positives = 725/725 (100%) Query: 1 MDSRTKGKTVMEVGGDGVAVITLINPPVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGA 60 MDSRTKGKTVMEVGGDGVAVITLINPPVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGA Sbjct: 1 MDSRTKGKTVMEVGGDGVAVITLINPPVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGA 60 Query: 61 KGRFSGGFDISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLEL 120 KGRFSGGFDISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLEL Sbjct: 61 KGRFSGGFDISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLEL 120 Query: 121 AMACHARISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHS 180 AMACHARISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHS Sbjct: 121 AMACHARISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHS 180 Query: 181 LGLIDAVVPPAELVTTARRWALDIVGRRKPWVSSVSKTDKLPPLGEAREILTFAKAQTLK 240 LGLIDAVVPPAELVTTARRWALDIVGRRKPWVSSVSKTDKLPPLGEAREILTFAKAQTLK Sbjct: 181 LGLIDAVVPPAELVTTARRWALDIVGRRKPWVSSVSKTDKLPPLGEAREILTFAKAQTLK 240 Query: 241 RAPNMKHPLMCLDAIEVGIVSGPRAGLEKEAEVASQVVKLDTTKGLIHVFFSQRGTAKVP 300 RAPNMKHPLMCLDAIEVGIVSGPRAGLEKEAEVASQVVKLDTTKGLIHVFFSQRGTAKVP Sbjct: 241 RAPNMKHPLMCLDAIEVGIVSGPRAGLEKEAEVASQVVKLDTTKGLIHVFFSQRGTAKVP 300 Query: 301 GVTDRGLVPRKIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQ 360 GVTDRGLVPRKIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQ Sbjct: 301 GVTDRGLVPRKIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQ 360 Query: 361 SRVRKGSMSQEKFEKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADLEKYCPQH 420 SRVRKGSMSQEKFEKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADLEKYCPQH Sbjct: 361 SRVRKGSMSQEKFEKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADLEKYCPQH 420 Query: 421 CILASNTSTIDLNKIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDVG 480 CILASNTSTIDLNKIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDVG Sbjct: 421 CILASNTSTIDLNKIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDVG 480 Query: 481 KKIKKTPVVVGNCTGFAVNRMFFPYTQAAMFLVECGADPYLIDRAISKFGMPMGPFRLCD 540 KKIKKTPVVVGNCTGFAVNRMFFPYTQAAMFLVECGADPYLIDRAISKFGMPMGPFRLCD Sbjct: 481 KKIKKTPVVVGNCTGFAVNRMFFPYTQAAMFLVECGADPYLIDRAISKFGMPMGPFRLCD 540 Query: 541 LVGFGVAIATATQFIENFSERTYKSMIIPLMQEDKRAGEATRKGFYLYDDKRKAKPDPEL 600 LVGFGVAIATATQFIENFSERTYKSMIIPLMQEDKRAGEATRKGFYLYDDKRKAKPDPEL Sbjct: 541 LVGFGVAIATATQFIENFSERTYKSMIIPLMQEDKRAGEATRKGFYLYDDKRKAKPDPEL 600 Query: 601 KKYIEKARSISGVKLDPKLANLSEKDIIEMTFFPVVNEACRVFAEGIAVKAADLDIAGIM 660 KKYIEKARSISGVKLDPKLANLSEKDIIEMTFFPVVNEACRVFAEGIAVKAADLDIAGIM Sbjct: 601 KKYIEKARSISGVKLDPKLANLSEKDIIEMTFFPVVNEACRVFAEGIAVKAADLDIAGIM 660 Query: 661 GMGFPPYRGGIMFWADSIGSKYIYSRLDEWSKAYGEFFKPCAFLAERGSKGVLLSAPVKQ 720 GMGFPPYRGGIMFWADSIGSKYIYSRLDEWSKAYGEFFKPCAFLAERGSKGVLLSAPVKQ Sbjct: 661 GMGFPPYRGGIMFWADSIGSKYIYSRLDEWSKAYGEFFKPCAFLAERGSKGVLLSAPVKQ 720 Query: 721 ASSRL 725 ASSRL Sbjct: 721 ASSRL 725 >6IUM-B nrPDB Length = 701 Score = 451 bits (1160), Expect = e-127, Method: Compositional matrix adjust. Identities = 270/699 (38%), Positives = 398/699 (56%), Gaps = 22/699 (3%) Query: 16 DGVAVITLINPPVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGFGE 75 DGVAVITL NPPVN L + AL VKAIVITGA FSGG DI F Sbjct: 9 DGVAVITLDNPPVNGLGHSTRLGIVEGMTRALDDAAVKAIVITGAGKAFSGGADIREFNT 68 Query: 76 MQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAAQL 135 + ++EP ++ + +LE + KP VAA+ +A+GGGLELA+ C+ R+++ AQ+ Sbjct: 69 PKA--MQEP-----TLHSVIRVLEGSSKPVVAAVHSVAMGGGLELALGCNYRVASKGAQI 121 Query: 136 GLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAELVT 195 LPE++LG++PG GGTQRLPR++GL A MI++ PV +E+ L D +V +++ Sbjct: 122 ALPEVKLGLLPGAGGTQRLPRVIGLEAAANMIVSGTPVLSEKFAGTKLFDEIVD-GDVLP 180 Query: 196 TARRWALDIVGRRKPWVSSVSKTDKLPPLGEARE-ILTFAKAQTLKRAPNMKHPLMCLDA 254 A ++A ++ P K L E E L FA+ A N PL CL+A Sbjct: 181 AAVKFAQNVGAATGPH----PKVRDLKVRHENPEGYLGFARNTVAAMAKNFPAPLKCLEA 236 Query: 255 IEVGIVSGPRAGLEKEAEVASQVVKLDTTKGLIHVFFSQRGTAKVPGVTDRGLVPRKIKK 314 + G + GL++E E +V ++ L H FF +R +K+P V + G RKI+K Sbjct: 237 V-AGSLKPFEQGLKQEREGFLYLVTTPESRALRHAFFGERAASKIPDVPE-GTPTRKIEK 294 Query: 315 VAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEKFE 374 VA+IG G MG GI+ + + PV + E ++ L+ G+G ++ N ++ +KG ++QEK E Sbjct: 295 VAVIGAGTMGGGISMNFLNAGIPVTILETKQEALDRGVGIIRKNYENSAKKGKLTQEKVE 354 Query: 375 KTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADLEKYCPQHCILASNTSTIDLNK 434 + M LL +L Y+ +D D++IEAV E + +K+ +F L++ Q ILASNTST+D+NK Sbjct: 355 QRMGLLSTTLSYDDLKDADLIIEAVFEEMGVKETVFKKLDEVAKQGAILASNTSTLDVNK 414 Query: 435 IGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDVGKKIKKTPVVVGNCT 494 I TK +VG HFFSPA++M LLE+VR T V+ ++ VGKKIKKT VV G C Sbjct: 415 IASFTKRPQDVVGMHFFSPANVMKLLEVVRGEKTGKDVLATVMQVGKKIKKTAVVSGVCD 474 Query: 495 GFAVNRMFFPYTQAAMFLVECGADPYLIDRAISKFGMPMGPFRLCDLVGFGVAIATATQF 554 GF NRM Y++ A +L++ GA P +D+AI KFG MGPFR+ DL G + A + Sbjct: 475 GFIGNRMIEQYSRQAGYLLDEGALPEQVDKAIEKFGFAMGPFRMGDLAGNDIGWAIRKRR 534 Query: 555 IENFSERTYKSMIIPLMQEDKRAGEATRKGFYLYD-DKRKAKPDPELKKYIEKARSISGV 613 + E Y S L+ E R G+ T G+Y Y RK P+ ++ I + G+ Sbjct: 535 AVDKPEIQY-SKTADLLCEMGRFGQKTGAGWYDYKAGDRKPYPNQQVNDMIVQHSKDLGI 593 Query: 614 KLDPKLANLSEKDIIEMTFFPVVNEACRVFAEGIAVKAADLDIAGIMGMGFPPYRGGIMF 673 +S+++I+E F +VNE R+ EGIA KA+D+D+ + G GFP +RGG M Sbjct: 594 ----TRRKISDEEIVERLVFALVNEGARILEEGIASKASDIDMVYLTGYGFPLFRGGPML 649 Query: 674 WADSIGSKYIYSRLDEWSKAY-GEFFKPCAFLAERGSKG 711 +AD +G + + ++K Y GE ++ L + +G Sbjct: 650 YADQVGLYNVALSMKRYAKGYHGEAWQVAPLLQKLADEG 688 >3ZWA-A nrPDB Length = 742 Score = 350 bits (898), Expect = 1e-96, Method: Compositional matrix adjust. Identities = 232/726 (31%), Positives = 386/726 (53%), Gaps = 43/726 (5%) Query: 18 VAVITLINPPVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGFGEMQ 77 +A+I L NPPVN++S V+ +++ ++A S + VKAIVI GA G F G DI GF Sbjct: 31 LAMIRLCNPPVNAVSPTVIREVRNGLQKAGSDHTVKAIVICGANGNFCAGADIHGFSAFT 90 Query: 78 KGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAAQLGL 137 G +++ + D ++ +KP +AAI G+ALGGGLELA+ CH RI+ A++GL Sbjct: 91 PG---------LALGSLVDEIQRYQKPVLAAIQGVALGGGLELALGCHYRIANAKARVGL 141 Query: 138 PELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAELVTTA 197 PE+ LG++PG GTQ LPR+VG+ AL++I + K + A+E LG++DAVV ++ V A Sbjct: 142 PEVTLGILPGARGTQLLPRVVGVPVALDLITSGKYLSADEALRLGILDAVVK-SDPVEEA 200 Query: 198 RRWALDIVGRRKPWVSSVSKTDKLPPLGEAREILTFAKAQTLKRAPNMKHPLMCLDAIEV 257 ++A I+ KP +P L + A A+ K+ P + P C+ +I+ Sbjct: 201 IKFAQKIID--KPIEPRRIFNKPVPSLPNMDSVFAEAIAKVRKQYPGVLAPETCVRSIQA 258 Query: 258 GIVSGPRAGLEKEAEVASQVVKLDTTKGLIHVFFSQRGTAKVP---GVTDRGLVPRKIKK 314 + G+++E ++ + K L + FF+++ K G + + + + Sbjct: 259 SVKHPYEVGIKEEEKLFMYLRASGQAKALQYAFFAEKSANKWSTPSGASWKTASAQPVSS 318 Query: 315 VAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEKFE 374 V ++G G MG GIA + V+ E + K L+A + L+ + + + Sbjct: 319 VGVLGLGTMGRGIAISFARVGISVVAVESDPKQLDAAKKIITFTLEKEASRAHQNGQASA 378 Query: 375 KTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADLEKYCPQHCILASNTSTIDLNK 434 K L+ S + VD+V+EAV E+++LK+++FA+L C L +NTS ++++ Sbjct: 379 KPK--LRFSSSTKELSTVDLVVEAVFEDMNLKKKVFAELSALCKPGAFLCTNTSALNVDD 436 Query: 435 IGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDVGKKIKKTPVVVGNCT 494 I T ++G HFFSPAH+M LLE++ + ++S I ++ + KKI K VVVGNC Sbjct: 437 IASSTDRPQLVIGTHFFSPAHVMRLLEVIPSRYSSPTTIATVMSLSKKIGKIGVVVGNCY 496 Query: 495 GFAVNRMFFPYTQAAMFLVECGADPYLIDRAISKFGMPMGPFRLCDLVGF---------- 544 GF NRM PY FL+E G+ P +D + +FG MGPFR+ DL G Sbjct: 497 GFVGNRMLAPYYNQGFFLLEEGSKPEDVDGVLEEFGFKMGPFRVSDLAGLDVGWKIRKGQ 556 Query: 545 ---GVAIATATQFIENFSERTYKSMIIPLMQEDKRAGEATRKGFYLYDDK--RKAKPDPE 599 G ++ T + + R S + ++ E R G+ T KG+Y YD R KPDP Sbjct: 557 GLTGPSLPPGTPVRKRGNSRY--SPLGDMLCEAGRFGQKTGKGWYQYDKPLGRIHKPDPW 614 Query: 600 LKKYIEKARSISGVKLDPKLANLSEKDIIEMTFFPVVNEACRVFAEGIAVKAADLDIAGI 659 L ++ + R + ++ +S+++I+E + ++NEA R+ EG+A + +D+ + Sbjct: 615 LSTFLSQYREVHHIEQR----TISKEEILERCLYSLINEAFRILEEGMAARPEHIDVIYL 670 Query: 660 MGMGFPPYRGGIMFWADSIGSKYIYSRLDEWSKAYGEF--FKPCAFLAERGSKGVLLSAP 717 G G+P ++GG MF+A S+G + +L ++ + + +P +L ++G S P Sbjct: 671 HGYGWPRHKGGPMFYAASVGLPTVLEKLQKYYRQNPDIPQLEPSDYLRRLVAQG---SPP 727 Query: 718 VKQASS 723 +K+ S Sbjct: 728 LKEWQS 733 >2D3T-A nrPDB Length = 715 Score = 348 bits (893), Expect = 4e-96, Method: Compositional matrix adjust. Identities = 234/699 (33%), Positives = 367/699 (52%), Gaps = 32/699 (4%) Query: 28 VNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGFGEMQKGNVKEPKAG 87 VN + L L+ + + VK ++++ K F G DI+ F E K E AG Sbjct: 29 VNKFNRLTLNELRQAVDAIKADASVKGVIVSSGKDVFIVGADITEFVENFKLPDAELIAG 88 Query: 88 YISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAAQLGLPELQLGVIPG 147 + + I E P+VAAI+G+ALGGGLE+ +A R+ A +A++GLPE++LG+ PG Sbjct: 89 NLEANKIFSDFEDLNVPTVAAINGIALGGGLEMCLAADFRVMADSAKIGLPEVKLGIYPG 148 Query: 148 FGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVV-------PPAELVTTARRW 200 FGGT RLPRL+G+ A+E I + K +AE+ + +DAVV +L+ A Sbjct: 149 FGGTVRLPRLIGVDNAVEWIASGKENRAEDALKVSAVDAVVTADKLGAAALDLIKRAISG 208 Query: 201 ALDIVGRRKPWVSSVSKTDKLPPLGEAREILTFAKAQTL---KRAPNMKHPLMCLDAIEV 257 LD +R+P K +KL L +++ F A+ + PN P+ + I+ Sbjct: 209 ELDYKAKRQP------KLEKLK-LNAIEQMMAFETAKGFVAGQAGPNYPAPVEAIKTIQK 261 Query: 258 GIVSGPRAGLEKEAEVASQVVKLDTTKGLIHVFFSQRGTAKVPGVTDRGLVPRKIKKVAI 317 G LE EA +++ K + LI +F + + K V D+ + + +K+ A+ Sbjct: 262 AANFGRDKALEVEAAGFAKLAKTSASNCLIGLFLNDQELKKKAKVYDK--IAKDVKQAAV 319 Query: 318 IGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEKFEKTM 377 +G G+MG GIA P+++K++NE +E G+ L RV KG M+ K + + Sbjct: 320 LGAGIMGGGIAYQSASKGTPILMKDINEHGIEQGLAEAAKLLVGRVDKGRMTPAKMAEVL 379 Query: 378 SLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADLEKYCPQHCILASNTSTIDLNKIGE 437 + ++ +L Y F +VD+V+EAV+EN +KQ + A++E + + ILASNTSTI ++ + + Sbjct: 380 NGIRPTLSYGDFGNVDLVVEAVVENPKVKQAVLAEVENHVREDAILASNTSTISISLLAK 439 Query: 438 RTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDVGKKIKKTPVVVGNCTGFA 497 K + VG HFF+P H+MPL+E++R +S + + KK+ K P+VV +C GF Sbjct: 440 ALKRPENFVGMHFFNPVHMMPLVEVIRGEKSSDLAVATTVAYAKKMGKNPIVVNDCPGFL 499 Query: 498 VNRMFFPYTQAAMFLVECGADPYLIDRAISKFGMPMGPFRLCDLVGFGVAIATATQFIEN 557 VNR+ FPY LV G D ID+ + KFG PMGP L D+VG E Sbjct: 500 VNRVLFPYFGGFAKLVSAGVDFVRIDKVMEKFGWPMGPAYLMDVVGIDTGHHGRDVMAEG 559 Query: 558 FSERTY--KSMIIPLMQEDKRAGEATRKGFYLYDDKRKAKPDPELKKYIEKARSISGVKL 615 F +R + I + E KR G+ KGFY Y+ +K K KK ++ S+ V L Sbjct: 560 FPDRMKDDRRSAIDALYEAKRLGQKNGKGFYAYEADKKGKQ----KKLVDS--SVLEV-L 612 Query: 616 DP---KLANLSEKDIIEMTFFPVVNEACRVFAEGIAVKAADLDIAGIMGMGFPPYRGGIM 672 P + +++++DII P+ E R +GI AA+ D+ + G+GFP +RGG + Sbjct: 613 KPIVYEQRDVTDEDIINWMMIPLCLETVRCLEDGIVETAAEADMGLVYGIGFPLFRGGAL 672 Query: 673 FWADSIGSKYIYSRLDEWSKAYGEFFKPCAFLAERGSKG 711 + DSIG + D++++ G + P A L E G Sbjct: 673 RYIDSIGVAEFVALADQYAE-LGALYHPTAKLREMAKNG 710 >5ZRV-A nrPDB Length = 763 Score = 326 bits (836), Expect = 2e-89, Method: Compositional matrix adjust. Identities = 230/732 (31%), Positives = 358/732 (48%), Gaps = 44/732 (6%) Query: 8 KTVMEVGGDGVAVITLINPP---VNSLSFDVLYNLKSNYEEALSRNDVK-AIVITGAKGR 63 +T + G G + IN P VN+LS ++ E + + ++ A++I+ G Sbjct: 38 RTHINYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGC 97 Query: 64 FSGGFDISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMA 123 F G DI+ + ++E I + LE + KP VAAI+G LGGGLE+A++ Sbjct: 98 FIAGADINMLAACK--TLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAIS 155 Query: 124 CHARISAPAAQ--LGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSL 181 C RI+ + LG PE+ LG +PG GGTQRLP++VG+ AL+M+LT + ++A+ + Sbjct: 156 CQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKM 215 Query: 182 GLIDAVV--------PPAE-----LVTTARRWALDIVGRRKPWVSSVSKTDKLPPLGEAR 228 GL+D +V PP E L A +A + ++ +S + L Sbjct: 216 GLVDQLVEPLGPGLKPPEERTIEYLEEVAITFAKGLADKK---ISPKRDKGLVEKLTAYA 272 Query: 229 EILTFAKAQTLKRAPN---------MKHPLMCLDAIEVGIVSGPRAGLEKEAEVASQVVK 279 + F + Q K+ PL +D ++ GI G AG E++ ++V Sbjct: 273 MTIPFVRQQVYKKVEEKVRKQTKGLYPAPLKIIDVVKTGIEQGSDAGYLCESQKFGELVM 332 Query: 280 LDTTKGLIHVFFSQRGTAKVPGVTDRGLVPRKIKKVAIIGGGLMGSGIATALILSNYPVI 339 +K L+ ++ Q K G + +K +AI+G GLMG+GIA + I Sbjct: 333 TKESKALMGLYHGQVLCKK----NKFGAPQKDVKHLAILGAGLMGAGIAQVSVDKGLKTI 388 Query: 340 LKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEKFEKTMSLLKGSLDYESFRDVDMVIEAV 399 LK+ L+ G +V L +V+K +++ + + S L G LDY+ F DMVIEAV Sbjct: 389 LKDATLTALDRGQQQVFKGLNDKVKKKALTSFERDSIFSNLTGQLDYQGFEKADMVIEAV 448 Query: 400 IENISLKQQIFADLEKYCPQHCILASNTSTIDLNKIGERTKSQDRIVGAHFFSPAHIMPL 459 E++SLK ++ ++E P HCI ASNTS + +++I +K ++++G H+FSP M L Sbjct: 449 FEDLSLKHRVLKEVEAVIPDHCIFASNTSALPISEIAAVSKRPEKVIGMHYFSPVDKMQL 508 Query: 460 LEIVRTNHTSAQVIVDLLDVGKKIKKTPVVVGNCTGFAVNRMFFPYTQAAMFLVECGADP 519 LEI+ T TS + VG K K +VV + GF R P + +++ G DP Sbjct: 509 LEIITTEKTSKDTSASAVAVGLKQGKVIIVVKDGPGFYTTRCLAPMMSEVIRILQEGVDP 568 Query: 520 YLIDRAISKFGMPMGPFRLCDLVGFGVAIATATQFIENFSER--TYKSMIIPLMQEDKRA 577 +D + FG P+G L D VG VA A + F ER ++ M Sbjct: 569 KKLDSLTTSFGFPVGAATLVDEVGVDVAKHVAEDLGKVFGERFGGGNPELLTQMVSKGFL 628 Query: 578 GEATRKGFYLYDDKRKAKPDPELKKYIEKARSISGVKLDPKLANLSEKDIIEMTFFPVVN 637 G + KGFY+Y + K K +L ++ ++ +KL PK S++DI VN Sbjct: 629 GRKSGKGFYIYQEGVKRK---DLNSDMDSI--LASLKLPPKSEVSSDEDIQFRLVTRFVN 683 Query: 638 EACRVFAEGIAVKAADLDIAGIMGMGFPPYRGGIMFWADSIGSKYIYSRLDEWSKAYGEF 697 EA EGI A+ DI + G+GFPP GG + D G++ I RL ++ AYG+ Sbjct: 684 EAVMCLQEGILATPAEGDIGAVFGLGFPPCLGGPFRFVDLYGAQKIVDRLKKYEAAYGKQ 743 Query: 698 FKPCAFLAERGS 709 F PC LA+ + Sbjct: 744 FTPCQLLADHAN 755 >4B3J-A nrPDB Length = 736 Score = 259 bits (662), Expect = 3e-69, Method: Compositional matrix adjust. Identities = 214/721 (29%), Positives = 344/721 (47%), Gaps = 55/721 (7%) Query: 16 DGVAVITLINPP--VNSLSFDVLYNLKSNYEEALSRND-VKAIVITGAKGRFSGGFDISG 72 DG+ +T+ +P N ++ + ++ + ++ D + +V+ AK F G D+ Sbjct: 29 DGIVTLTMDDPSGSTNVMNEAYIESMGKAVDRLVAEKDSITGVVVASAKKTFFAGGDVKT 88 Query: 73 FGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISA-- 130 + + + + +I LE KP VAAI+G ALGGGLE+A+ACH RI+A Sbjct: 89 MIQARPEDAGDVFNTVETIKRQLRTLETLGKPVVAAINGAALGGGLEIALACHHRIAADV 148 Query: 131 PAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTS----KPVKAEEGHSLGLIDA 186 +QLGLPE+ LG++PG GG R R+ G+ A +L KP KA+E +GL+D Sbjct: 149 KGSQLGLPEVTLGLLPGGGGVTRTVRMFGIQNAFVSVLAQGTRFKPAKAKE---IGLVDE 205 Query: 187 VVPPAE-LVTTARRWALDIVGRR------KPWVSSVSK----TDKLPPLGEAREILTFAK 235 +V E LV A+ W + + +PW K T P L Sbjct: 206 LVATVEELVPAAKAWIKEELKANPDGAGVQPWDKKGYKMPGGTPSSPGLAAILPSFPSNL 265 Query: 236 AQTLKRAPNMKHPLMCLDAIEVGIVSGPRAGLEKEAEVASQ----VVKLDTTKGLIHVFF 291 + LK AP M P L A V G + + + + S+ +V K ++ FF Sbjct: 266 RKQLKGAP-MPAPRAILAAA----VEGAQVDFDTASRIESRYFASLVTGQVAKNMMQAFF 320 Query: 292 SQRGTAKVPGVTDRGLVPRKIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAG 351 G G+ IK++ ++G G+MG+GIA + Y V+LK+V+ + G Sbjct: 321 FDLQAINAGGSRPEGIGKTPIKRIGVLGAGMMGAGIAYVSAKAGYEVVLKDVSLEAAAKG 380 Query: 352 IGRVKANLQSRVRKGSMSQEKFEKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFA 411 G + + +G +QE+ + ++ + + D F+ VD VIEAV EN LK ++F Sbjct: 381 KGYSEKLEAKALERGRTTQERSDALLARITPTADAADFKGVDFVIEAVFENQELKHKVFG 440 Query: 412 DLEKYCPQHCILASNTSTIDLNKIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQ 471 ++E + IL SNTST+ + + K Q+ +G HFFSP MPL+EI++ TS + Sbjct: 441 EIEDIVEPNAILGSNTSTLPITGLATGVKRQEDFIGIHFFSPVDKMPLVEIIKGEKTSDE 500 Query: 472 VIVDLLDVGKKIKKTPVVVGNCTGFAVNRMFFPYTQAAMFLVECGADPYLIDRAISKFGM 531 + + D I KTP+VV + GF +R+ + A+ ++ G +P I++A S+ G Sbjct: 501 ALARVFDYTLAIGKTPIVVNDSRGFFTSRVIGTFVNEALAMLGEGVEPASIEQAGSQAGY 560 Query: 532 PMGPFRLCDLVGFGV--AIATATQFIENFSERTYK----SMIIPLMQEDKRAGEATRKGF 585 P P +L D + + IA AT+ + TY+ ++ M E R+G GF Sbjct: 561 PAPPLQLSDELNLELMHKIAVATRKGVEDAGGTYQPHPAEAVVEKMIELGRSGRLKGAGF 620 Query: 586 YLYDDKRKAKPDPELKKYIEKARSISGVKLDPKLANLSEKDIIEMTFFPVVNEACRVFAE 645 Y Y D +++ P L++ + S P L +D+I+ F E + E Sbjct: 621 YEYADGKRSGLWPGLRETFKSGSS------QPPL-----QDMIDRMLFAEALETQKCLDE 669 Query: 646 GIAVKAADLDIAGIMGMGFPPYRGG----IMFWADSIGS--KYIYSRLDEWSKAYGEFFK 699 G+ AD +I IMG+GFPP+ GG I+ ++ G+ +R E + AYG+ F Sbjct: 670 GVLTSTADANIGSIMGIGFPPWTGGSAQFIVGYSGPAGTGKAAFVARARELAAAYGDRFL 729 Query: 700 P 700 P Sbjct: 730 P 730 >1ZCJ-A nrPDB Length = 463 Score = 227 bits (579), Expect = 1e-59, Method: Compositional matrix adjust. Identities = 138/460 (30%), Positives = 236/460 (51%), Gaps = 31/460 (6%) Query: 284 KGLIHVFFSQRGTAKVP---GVTDRGLVPRKIKKVAIIGGGLMGSGIATALILSNYPVIL 340 K L + FF+++ K G + + + + V ++G G MG GIA + V+ Sbjct: 6 KALQYAFFAEKSANKWSTPSGASWKTASAQPVSSVGVLGLGTMGRGIAISFARVGISVVA 65 Query: 341 KEVNEKFLEAGIGRVKANLQSRVRKGSMSQEKFEKTMSLLKGSLDYESFRDVDMVIEAVI 400 E + K L+A + L+ + + + K L+ S + VD+V+EAV Sbjct: 66 VESDPKQLDAAKKIITFTLEKEASRAHQNGQASAKPK--LRFSSSTKELSTVDLVVEAVF 123 Query: 401 ENISLKQQIFADLEKYCPQHCILASNTSTIDLNKIGERTKSQDRIVGAHFFSPAHIMPLL 460 E+++LK+++FA+L C L +NTS ++++ I T ++G HFFSPAH+M LL Sbjct: 124 EDMNLKKKVFAELSALCKPGAFLCTNTSALNVDDIASSTDRPQLVIGTHFFSPAHVMRLL 183 Query: 461 EIVRTNHTSAQVIVDLLDVGKKIKKTPVVVGNCTGFAVNRMFFPYTQAAMFLVECGADPY 520 E++ + ++S I ++ + KKI K VVVGNC GF NRM PY FL+E G+ P Sbjct: 184 EVIPSRYSSPTTIATVMSLSKKIGKIGVVVGNCYGFVGNRMLAPYYNQGFFLLEEGSKPE 243 Query: 521 LIDRAISKFGMPMGPFRLCDLVGF-------------GVAIATATQFIENFSERTYKSMI 567 +D + +FG MGPFR+ DL G G ++ T + + R S + Sbjct: 244 DVDGVLEEFGFKMGPFRVSDLAGLDVGWKIRKGQGLTGPSLPPGTPVRKRGNSRY--SPL 301 Query: 568 IPLMQEDKRAGEATRKGFYLYDDK--RKAKPDPELKKYIEKARSISGVKLDPKLANLSEK 625 ++ E R G+ T KG+Y YD R KPDP L ++ + R + ++ +S++ Sbjct: 302 GDMLCEAGRFGQKTGKGWYQYDKPLGRIHKPDPWLSTFLSQYREVHHIEQR----TISKE 357 Query: 626 DIIEMTFFPVVNEACRVFAEGIAVKAADLDIAGIMGMGFPPYRGGIMFWADSIGSKYIYS 685 +I+E + ++NEA R+ EG+A + +D+ + G G+P ++GG MF+A S+G + Sbjct: 358 EILERCLYSLINEAFRILEEGMAARPEHIDVIYLHGYGWPRHKGGPMFYAASVGLPTVLE 417 Query: 686 RLDEWSKAYGEF--FKPCAFLAERGSKGVLLSAPVKQASS 723 +L ++ + + +P +L ++G S P+K+ S Sbjct: 418 KLQKYYRQNPDIPQLEPSDYLRRLVAQG---SPPLKEWQS 454 >3K6J-A nrPDB Length = 460 Score = 221 bits (562), Expect = 1e-57, Method: Compositional matrix adjust. Identities = 134/382 (35%), Positives = 205/382 (53%), Gaps = 15/382 (3%) Query: 312 IKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQE 371 + VAIIGGG MG +A L+ L NE+ + + + A +S R ++ + Sbjct: 54 VNSVAIIGGGTMGKAMAICFGLAGIETFLVVRNEQRCKQELEVMYAREKSFKR---LNDK 110 Query: 372 KFEKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADLEKYCPQHCILASNTSTID 431 + EK + LK + D+ + D+++E+VIE++ LK+++FA+LE C CI +NTS++D Sbjct: 111 RIEKINANLKITSDFHKLSNCDLIVESVIEDMKLKKELFANLENICKSTCIFGTNTSSLD 170 Query: 432 LNKIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDVGKKIKKTPVVVG 491 LN+I + +VG HFF+PA+++ L+EI+ +HTS+Q I + IKK PV+VG Sbjct: 171 LNEISSVLRDPSNLVGIHFFNPANVIRLVEIIYGSHTSSQAIATAFQACESIKKLPVLVG 230 Query: 492 NCTGFAVNRMFFPY-TQAAMFLVECGADPYLIDRAISKFGMPMGPFRLCDLVGFGVAIAT 550 NC F NR+ Y Q+ + E G P+ ID+ I+ FG MGP + D+ GF V Sbjct: 231 NCKSFVFNRLLHVYFDQSQKLMYEYGYLPHQIDKIITNFGFLMGPMTVADMNGFDVMEKL 290 Query: 551 ATQFIENFSERTYKSMIIPLMQEDKRAGEATRKGFYLYDDKRKAKP-DPELKKYIEKARS 609 EN E + I M KR G T KGFY YDDK + K D E+++ I R Sbjct: 291 KK---ENGLE---PNPIEKEMWRLKRYGRKTNKGFYKYDDKTQRKENDTEMEQIIR--RV 342 Query: 610 ISGVKLDPKLANLSEKDIIEMTFFPVVNEACRVFAEGIAVKAADLDIAGIMGMGFPPYRG 669 K + ++ N ++D+I +P VNE R EG+ + +DI I+G G+P + G Sbjct: 343 SQNAKSNIQIIN--DQDVINFMLYPTVNEGYRCIEEGVISNESLIDIMFILGFGWPIHSG 400 Query: 670 GIMFWADSIGSKYIYSRLDEWS 691 G M + + G I + L WS Sbjct: 401 GPMRFGKTEGLDKIANMLVHWS 422 >6ACQ-A nrPDB Length = 302 Score = 181 bits (458), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 105/291 (36%), Positives = 161/291 (55%), Gaps = 11/291 (3%) Query: 306 GLVPR--KIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRV 363 GLVPR +KKV +IG G MGSGIA A + V+L+++ ++F++ G+ + NL V Sbjct: 13 GLVPRGSHMKKVCVIGAGTMGSGIAQAFAAKGFEVVLRDIKDEFVDRGLDFINKNLSKLV 72 Query: 364 RKGSMSQEKFEKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADLEKYCPQHCIL 423 +KG + + + ++ + G++D D D+VIEA +E + +K+QIFADL+ C IL Sbjct: 73 KKGKIEEATKVEILTRISGTVDLNMAADCDLVIEAAVERMDIKKQIFADLDNICKPETIL 132 Query: 424 ASNTSTIDLNKIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDVGKKI 483 ASNTS++ + ++ TK D+++G HFF+PA +M L+E++R TS + + + I Sbjct: 133 ASNTSSLSITEVASATKRPDKVIGMHFFNPAPVMKLVEVIRGIATSQETFDAVKETSIAI 192 Query: 484 KKTPVVVGNCTGFAVNRMFFPYTQAAM-FLVECGADPYLIDRAISKFG--MPMGPFRLCD 540 K PV V GF VNR+ P A+ L E A ID+A+ K G PMGP L D Sbjct: 193 GKDPVEVAEAPGFVVNRILIPMINEAVGILAEGIASVEDIDKAM-KLGANHPMGPLELGD 251 Query: 541 LVGFGVAIATATQFIENFSERTYKSMIIPLMQEDKRAGEATR---KGFYLY 588 +G + +A + Y+ L+++ RAG R KGFY Y Sbjct: 252 FIGLDICLAIMDVLYSETGDSKYRPH--TLLKKYVRAGWLGRKSGKGFYDY 300 >4KUG-A nrPDB Length = 290 Score = 177 bits (450), Expect = 1e-44, Method: Compositional matrix adjust. Identities = 101/287 (35%), Positives = 162/287 (56%), Gaps = 9/287 (3%) Query: 312 IKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQE 371 +KKV ++G G MG+GI A VI++++ E+F++ GI + +L V K +++ Sbjct: 1 MKKVFVLGAGTMGAGIVQAFAAKGCEVIVRDIKEEFVDRGIATITKSLSKLVAKEKITEA 60 Query: 372 KFEKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADLEKYCPQHCILASNTSTID 431 E+ +S + G+ D + D D+V+EA IEN+ +K++IFA+L+ C ILASNTS++ Sbjct: 61 DKEEILSRISGTTDMKLAADCDLVVEAAIENMKIKKEIFAELDGICKPETILASNTSSLS 120 Query: 432 LNKIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDVGKKIKKTPVVVG 491 + ++ TK D+++G HFF+PA +M L+E++R TS + + ++ + I KTPV V Sbjct: 121 ITEVASATKRADKVIGMHFFNPAPVMKLVEVIRGAATSQETFDAVKEMSESIGKTPVEVA 180 Query: 492 NCTGFAVNRMFFPYTQAAMFLVECG-ADPYLIDRAISKFG--MPMGPFRLCDLVGFGVAI 548 GF VNR+ P A F+++ G A ID A+ K G PMGP L DL+G V + Sbjct: 181 EAPGFVVNRILIPMINEATFILQEGVAKEEDIDAAM-KLGANHPMGPLALGDLIGLDVCL 239 Query: 549 ATATQFIENFSERTYKSMIIPLMQEDKRA---GEATRKGFYLYDDKR 592 A + Y++ L+++ RA G T KGFY Y + Sbjct: 240 AIMDVLYNETGDTKYRAS--SLLRKYVRAGWLGRKTGKGFYDYSKSK 284 >3MOG-A nrPDB Length = 483 Score = 173 bits (439), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 130/468 (27%), Positives = 213/468 (45%), Gaps = 74/468 (15%) Query: 311 KIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQ 370 ++ VA+IG G MG+GIA + V+L +++ + L I + A L SRV +G ++ Sbjct: 4 NVQTVAVIGSGTMGAGIAEVAASHGHQVLLYDISAEALTRAIDGIHARLNSRVTRGKLTA 63 Query: 371 EKFEKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADLEKYCPQHCILASNTSTI 430 E E+T+ L D + D+VIEA E + +K+ +FA L + CP +L +NTS+I Sbjct: 64 ETCERTLKRLIPVTDIHALAAADLVIEAASERLEVKKALFAQLAEVCPPQTLLTTNTSSI 123 Query: 431 DLNKIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDVGKKIKKTPVVV 490 + I K+ +R+ G HFF+PA +M L+E+V T+A+V+ L ++ K PV Sbjct: 124 SITAIAAEIKNPERVAGLHFFNPAPVMKLVEVVSGLATAAEVVEQLCELTLSWGKQPVRC 183 Query: 491 GNCTGFAVNRMFFP-YTQAAMFLVECGADPYLIDRAISK-FGMPMGPFRLCDLVGFGVAI 548 + GF VNR+ P Y++A L E A P +ID A+ G PMGP L DL+G V Sbjct: 184 HSTPGFIVNRVARPYYSEAWRALEEQVAAPEVIDAALRDGAGFPMGPLELTDLIGQDVNF 243 Query: 549 A-TATQFIENFSERTY------KSMII--------------------------------- 568 A T + F + ER + + ++I Sbjct: 244 AVTCSVFNAFWQERRFLPSLVQQELVIGGRLGKKSGLGVYDWRAEREAVVGLEAVSDSFS 303 Query: 569 PLMQEDKRAGEATRKGFYLYDDK---------RKAKPDPELKKYIEKARSISGVKLDPKL 619 P+ E K G L + + R A+P + K K +I+ ++P Sbjct: 304 PMKVEKKSDGVTEIDDVLLIETQGETAQALAIRLARPVVVIDKMAGKVVTIAAAAVNPDS 363 Query: 620 ANLSE--------KDIIEMTFFP----------VVNEACRVFAEGIAVKAADLDIAGIMG 661 A K ++++ +P ++NEA +G+A + D+D A +G Sbjct: 364 ATRKAIYYLQQQGKTVLQIADYPGMLIWRTVAMIINEALDALQKGVASE-QDIDTAMRLG 422 Query: 662 MGFPPYRGGIMFWADSIGSKYIYSRLDEWSKAYG-EFFKPCAFLAERG 708 + +P G + W +G + I L+ YG E ++PC+ L +R Sbjct: 423 VNYP---YGPLAWGAQLGWQRILRLLENLQHHYGEERYRPCSLLRQRA 467 >1F14-A nrPDB Length = 310 Score = 161 bits (408), Expect = 9e-40, Method: Compositional matrix adjust. Identities = 103/295 (34%), Positives = 153/295 (51%), Gaps = 26/295 (8%) Query: 312 IKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKG----- 366 +K V +IGGGLMG+GIA + + V+L + E L ++ +L+ +K Sbjct: 15 VKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENP 74 Query: 367 SMSQEKFEKTMSLLKGSLDYESF-RDVDMVIEAVIENISLKQQIFADLEKYCPQHCILAS 425 E EKT+S + S D S D+V+EA++EN+ +K ++F L+K+ +H I AS Sbjct: 75 KAGDECVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFAS 134 Query: 426 NTSTIDLNKIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDVGKKIKK 485 NTS++ + I T QDR G HFF+P +M L+E+++T TS + L+D K + K Sbjct: 135 NTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGK 194 Query: 486 TPVVVGNCTGFAVNRMFFPYTQAAMFLVECG-ADPYLIDRAIS-KFGMPMGPFRLCDLVG 543 PV + GF VNR+ PY A+ L E G A ID A+ G PMGPF L D VG Sbjct: 195 HPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYPMGPFELLDYVG 254 Query: 544 FGVAIATATQFI-ENFSERTYKSMIIPLMQ---------EDKRAGEATRKGFYLY 588 T+FI + + E ++ PL Q + + G+ T +GFY Y Sbjct: 255 LDT-----TKFIVDGWHEMDAEN---PLHQPSPSLNKLVAENKFGKKTGEGFYKY 301 >3HDH-A nrPDB Length = 302 Score = 160 bits (406), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 103/297 (34%), Positives = 159/297 (53%), Gaps = 30/297 (10%) Query: 312 IKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQE 371 +K V +IGGGLMG+GIA + + V+L + E L + K ++ +RK ++++ Sbjct: 15 VKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDIL----AKSKKGIEESLRK--VAKK 68 Query: 372 KF-----------EKTMSLLKGSLDYESF-RDVDMVIEAVIENISLKQQIFADLEKYCPQ 419 KF EKT+S + S D S D+V+EA++EN+ +K ++F L+K+ + Sbjct: 69 KFAENPKAGDEFVEKTLSSISTSTDAASVVHSTDLVVEAIVENLKVKSELFKRLDKFAAE 128 Query: 420 HCILASNTSTIDLNKIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDV 479 H I ASNTS++ + + T QDR G HFF+P +M L+E+V+T TS + + L+D Sbjct: 129 HTIFASNTSSLQITSLANATTRQDRFAGLHFFNPVPLMKLVEVVKTPMTSQKTLESLVDF 188 Query: 480 GKKIKKTPVVVGNCTGFAVNRMFFPYTQAAMFLVECG-ADPYLIDRAIS-KFGMPMGPFR 537 K + K PV + GF VNR+ PY A+ L E G A ID A+ G PMGPF Sbjct: 189 SKTLGKHPVSCKDTPGFIVNRLLVPYLIEAVRLYERGDASKEDIDTAMKLGAGYPMGPFE 248 Query: 538 LCDLVGFGVAIATATQFIENFSERTYKSMII---PLMQE---DKRAGEATRKGFYLY 588 L D VG + T I+ + E ++ + P M + + + G+ T +GFY Y Sbjct: 249 LLDYVG----LDTTKFIIDGWHEMDSQNPLFQPSPAMNKLVAENKFGKKTGEGFYKY 301 >6HRD-A nrPDB Length = 317 Score = 157 bits (398), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 100/294 (34%), Positives = 156/294 (53%), Gaps = 11/294 (3%) Query: 306 GLVPR------KIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANL 359 GLVPR I++V ++G G MGSGIA + V + E E + AG R+ +L Sbjct: 13 GLVPRGSHMSDAIQRVGVVGAGQMGSGIAEVSARAGVEVTVFEPAEALITAGRNRIVKSL 72 Query: 360 QSRVRKGSMSQEKFEKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADLEKYCPQ 419 + V G +++ + ++ + LL + D D +VIEAV+E+ ++K +IFA+L++ Sbjct: 73 ERAVSAGKVTERERDRALGLLTFTTDLNDLSDRQLVIEAVVEDEAVKSEIFAELDRVVTD 132 Query: 420 -HCILASNTSTIDLNKIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLD 478 +LASNTS+I + K+ TK R++G HFF+P ++PL+E+VRT T + Sbjct: 133 PDAVLASNTSSIPIMKVAAATKQPQRVLGLHFFNPVPVLPLVELVRTLVTDEAAAARTEE 192 Query: 479 VGKKIKKTPVV-VGNCTGFAVNRMFFPYTQAAMFLVECG-ADPYLIDRA-ISKFGMPMGP 535 + VV + +GF VN + PY +A+ +VE G A +D+A ++ PMGP Sbjct: 193 FASTVLGKQVVRCSDRSGFVVNALLVPYLLSAIRMVEAGFATVEDVDKAVVAGLSHPMGP 252 Query: 536 FRLCDLVGFGVAIATATQFIENFSERTYKSMIIPL-MQEDKRAGEATRKGFYLY 588 RL DLVG A + E F E Y + L M E + G+ + +GFY Y Sbjct: 253 LRLSDLVGLDTLKLIADKMFEEFKEPHYGPPPLLLRMVEAGQLGKKSGRGFYTY 306 >4PZE-A nrPDB Length = 284 Score = 154 bits (388), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 87/281 (30%), Positives = 149/281 (53%), Gaps = 5/281 (1%) Query: 312 IKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQE 371 I+ V I+G G MG+GIA A + V++ ++++ ++ G+ V ++L ++K +++ Sbjct: 3 IRTVGIVGAGTMGNGIAQACAVVGLNVVMVDISDAAVQKGVATVASSLDRLIKKEKLTEA 62 Query: 372 KFEKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADLEKYCPQHCILASNTSTID 431 ++ +KGS Y+ + D+VIEA EN LK +I ++ ++ I+ASNTS+I Sbjct: 63 DKASALARIKGSTSYDDLKATDIVIEAATENYDLKVKILKQIDGIVGENVIIASNTSSIS 122 Query: 432 LNKIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDVGKKIKKTPVVVG 491 + K+ T DR +G HFF+P +M L+E++R TS + + K++ K P+ V Sbjct: 123 ITKLAAVTSRADRFIGMHFFNPVPVMALVELIRGLQTSDTTHAAVEALSKQLGKYPITVK 182 Query: 492 NCTGFAVNRMFFPYTQAAMFLVECG-ADPYLIDRAISKFGM--PMGPFRLCDLVGFGVAI 548 N GF VNR+ P A ++ G A P ID + K G P+GP L D++G + Sbjct: 183 NSPGFVVNRILCPMINEAFCVLGEGLASPEEIDEGM-KLGCNHPIGPLALADMIGLDTML 241 Query: 549 ATATQFIENFSERTYK-SMIIPLMQEDKRAGEATRKGFYLY 588 A F++ Y+ +M++ M G T +G Y+Y Sbjct: 242 AVMEVLYTEFADPKYRPAMLMREMVAAGYLGRKTGRGVYVY 282 >4J0E-A nrPDB Length = 320 Score = 148 bits (374), Expect = 7e-36, Method: Compositional matrix adjust. Identities = 99/289 (34%), Positives = 152/289 (52%), Gaps = 11/289 (3%) Query: 310 RKIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQ--SRVRKGS 367 + I+ VAI+G G MGSGIA S + V+L +VN+K L+ + + ++ S+ +KG+ Sbjct: 12 QNIRNVAIVGSGQMGSGIAQVTASSGFNVMLADVNKKALDRAMKAISQSVTHLSKKQKGT 71 Query: 368 MSQEKFE---KTMSLLKGSLDYES-FRDVDMVIEAVIENISLKQQIFADLEKYCPQHCIL 423 +EK + TMS +K + + D D++IEA IENI LK+ IFA +E+ C + IL Sbjct: 72 -DKEKSDFVTLTMSRIKTCNNVSTAVADADLIIEAAIENIDLKRGIFAQIEQSCKKDSIL 130 Query: 424 ASNTSTIDLNKIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDVGKKI 483 +NTS+ L + + + + R G HFF+P +M LLE++R++ TS + L+ G + Sbjct: 131 TTNTSSFLLEDVAKGLQDKTRFGGLHFFNPVPVMKLLEVIRSDDTSDETYATLIKFGTAV 190 Query: 484 KKTPVVVGNCTGFAVNRMFFPYTQAAMFLVECG-ADPYLIDRAIS-KFGMPMGPFRLCDL 541 KT V + GF VNR+ PY A + E G A ID A+ G PMGPF L D Sbjct: 191 GKTTVACKDSPGFIVNRLLIPYFFEAARMYERGDASMTDIDEAMKLGAGHPMGPFELADY 250 Query: 542 VGFGVAIATATQFIENFSERTY--KSMIIPLMQEDKRAGEATRKGFYLY 588 +G + + E S ++ + + + G T GFY Y Sbjct: 251 IGLDTVKFVMDGWAAKYPEVQLFEASPLVDKLVAEGKLGRKTGDGFYSY 299 >5Z7R-A nrPDB Length = 267 Score = 137 bits (345), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 80/190 (42%), Positives = 121/190 (63%), Gaps = 5/190 (2%) Query: 18 VAVITLINP-PVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGA-KGRFSGGFDISGFGE 75 VAV+T+ P +N+L+ D L + E + ++V A+++TGA + F G DIS E Sbjct: 14 VAVVTINRPKALNALNSDTLKEMDYVIGEIENDSEVLAVILTGAGEKSFVAGADIS---E 70 Query: 76 MQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAAQL 135 M++ N E + I + + LE KP +AA++G ALGGG E+AM+C RI++ A+ Sbjct: 71 MKEMNTIEGRKFGILGNKVFRRLELLEKPVIAAVNGFALGGGCEIAMSCDIRIASSNARF 130 Query: 136 GLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAELVT 195 G PE+ LG+ PGFGGTQRL RLVG+ A ++I T++ +KA+E +GL++ VV P+EL+ Sbjct: 131 GQPEVGLGITPGFGGTQRLSRLVGMGMAKQLIFTAQNIKADEALRIGLVNKVVEPSELMN 190 Query: 196 TARRWALDIV 205 TA+ A IV Sbjct: 191 TAKEIANKIV 200 >5ZAI-A nrPDB Length = 259 Score = 134 bits (336), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 79/186 (42%), Positives = 111/186 (59%), Gaps = 6/186 (3%) Query: 21 ITLINP-PVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGFGEMQKG 79 ITL P +N+L+ +L L +A S +++ I+ITG F G DI+ F ++ Sbjct: 17 ITLNRPDKLNALNAKLLEELDRAVSQAESDPEIRVIIITGKGKAFCAGADITQFNQLTPA 76 Query: 80 NV-KEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAAQLGLP 138 K K G I D +EA KP++A I+G ALGGGLELA+AC RI+A AQLGLP Sbjct: 77 EAWKFSKKGRE----IMDKIEALSKPTIAMINGYALGGGLELALACDIRIAAEEAQLGLP 132 Query: 139 ELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAELVTTAR 198 E+ LG+ PG+GGTQRL R++G +ALEM++T + ++ GL++ VVP A L R Sbjct: 133 EINLGIYPGYGGTQRLTRVIGKGRALEMMMTGDRIPGKDAEKYGLVNRVVPLANLEQETR 192 Query: 199 RWALDI 204 + A I Sbjct: 193 KLAEKI 198 >3H81-A nrPDB Length = 278 Score = 124 bits (310), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 74/190 (38%), Positives = 106/190 (55%), Gaps = 10/190 (5%) Query: 18 VAVITLINP-PVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGFGEM 76 V +ITL P +N+L+ V+ + S E D+ AI+ITG+ F+ G DI ++ Sbjct: 35 VGIITLNRPQALNALNSQVMNEVTSAATELDDDPDIGAIIITGSAKAFAAGADIKEMADL 94 Query: 77 QKGNVKEPKAGYISIDIITDL--LEAARKPSVAAIDGLALGGGLELAMACHARISAPAAQ 134 + + D L A R P++AA+ G ALGGG ELAM C I+A A+ Sbjct: 95 TFADA-------FTADFFATWGKLAAVRTPTIAAVAGYALGGGCELAMMCDVLIAADTAK 147 Query: 135 LGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAELV 194 G PE++LGV+PG GG+QRL R +G KA+++ILT + + A E GL+ VVP +L+ Sbjct: 148 FGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLVSRVVPADDLL 207 Query: 195 TTARRWALDI 204 T AR A I Sbjct: 208 TEARATATTI 217 >5JBW-A nrPDB Length = 260 Score = 114 bits (286), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 73/181 (40%), Positives = 104/181 (57%), Gaps = 10/181 (5%) Query: 29 NSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGR-FSGGFDISGFGEMQKGNVKEPKAG 87 N++S +L L S DV+A+VITGA + F G D+ M + V+ Sbjct: 26 NAISRAMLKELGELVTRVSSSRDVRAVVITGAGDKAFCAGADLKERATMAEDEVR----- 80 Query: 88 YISIDIITDLLEAARKPS---VAAIDGLALGGGLELAMACHARISAPAAQLGLPELQLGV 144 +D + A K +AAI+G ALGGG ELA+AC R++APAA+LGL E++LG+ Sbjct: 81 -AFLDGLRRTFRAIEKSDCVFIAAINGAALGGGTELALACDLRVAAPAAELGLTEVKLGI 139 Query: 145 IPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAELVTTARRWALDI 204 IPG GGTQRL RLVG +A ++ILT++ + A E S+GL + + P L+ A A + Sbjct: 140 IPGGGGTQRLARLVGPGRAKDLILTARRINAAEAFSVGLANRLAPEGHLLAVAYGLAESV 199 Query: 205 V 205 V Sbjct: 200 V 200 >3MOY-A nrPDB Length = 263 Score = 114 bits (285), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 73/197 (37%), Positives = 109/197 (55%), Gaps = 10/197 (5%) Query: 17 GVAVITLINP-PVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGFGE 75 GV +I L P +N+L+ + + + + ++ AIV+TG++ F+ G DI+ Sbjct: 19 GVGLIRLDRPDALNALNQTLEAEVLDAARDFDADLEIGAIVVTGSERAFAAGADIAEMVT 78 Query: 76 MQKGNVKEPK--AGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAA 133 + +E +G+ D L RKP VAA+ G ALGGG ELAM C I+A A Sbjct: 79 LTPHQARERNLLSGW-------DSLTQVRKPIVAAVAGYALGGGCELAMLCDLVIAADTA 131 Query: 134 QLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAEL 193 + G PE+ LG++PG GGTQRL R VG KA+++ LT + + AEE +GL+ +VP A+L Sbjct: 132 RFGQPEITLGILPGLGGTQRLTRAVGKAKAMDLCLTGRSLTAEEAERVGLVSRIVPAADL 191 Query: 194 VTTARRWALDIVGRRKP 210 + A A I +P Sbjct: 192 LDEALAVAQRIARMSRP 208 >1ZEJ-A nrPDB Length = 293 Score = 112 bits (279), Expect = 7e-25, Method: Compositional matrix adjust. Identities = 92/299 (30%), Positives = 145/299 (48%), Gaps = 33/299 (11%) Query: 314 KVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEKF 373 KV +IG GLMG GIA A I S + V+L++V+EK LEA ++ L S++ +F Sbjct: 14 KVFVIGAGLMGRGIAIA-IASKHEVVLQDVSEKALEAAREQIPEELLSKI--------EF 64 Query: 374 EKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADLEKYCPQHCILASNTSTIDLN 433 T+ E +D D+V+EAV E+++ K ++ ++E+ + L SNTS I ++ Sbjct: 65 TTTL---------EKVKDCDIVMEAVFEDLNTKVEVLREVERLT--NAPLCSNTSVISVD 113 Query: 434 KIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDVGKKIKKTPVVVGNC 493 I ER S R +G H+ +P H+MPL+EIV + T ++ + + +++ K VV C Sbjct: 114 DIAERLDSPSRFLGVHWMNPPHVMPLVEIVISRFTDSKTVAFVEGFLRELGKEVVV---C 170 Query: 494 TGFA-VNRMFFPYTQAAMFLVECGADPYLIDRAI-SKFGM---PMGPFRLCDLVGFGVAI 548 G + VNR A ++E G +DR G+ GP D +G VA Sbjct: 171 KGQSLVNRFNAAVLSEASRMIEEGVRAEDVDRVWKHHLGLLYTLFGPLGNLDYIGLDVAY 230 Query: 549 ATATQFIENFSERTYKSMIIPLMQEDKRAGEA---TRKGFYLYDDKRKAKPDPELKKYI 604 + + F + +K +QE + GE KG Y Y K + LKK + Sbjct: 231 YASLYLYKRFGDEKFKPP--EWLQEKIKKGEVGVKAGKGIYEYGPKAYEERVERLKKLL 287 >5WYB-B nrPDB Length = 280 Score = 111 bits (278), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 68/177 (38%), Positives = 100/177 (56%), Gaps = 6/177 (3%) Query: 18 VAVITLINPPVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRF-SGGFDISGFGEM 76 A+IT+ +PP N+ D L L+ E +D+ A+V+TG +F S G D++ F + Sbjct: 27 TALITINHPPANTWDRDSLIGLRQLIEHLNRDDDIYALVVTGQGPKFFSAGADLNMFADG 86 Query: 77 QKGNVKEPKAGY-ISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAAQL 135 K +E + + + + D R S+AAI+G A+GGGLE A+AC RI+ AQ+ Sbjct: 87 DKARAREMARRFGEAFEALRDF----RGVSIAAINGYAMGGGLECALACDIRIAERQAQM 142 Query: 136 GLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAE 192 LPE +G++P GGTQ LP LVG A MIL ++ V AE +GL++ VV E Sbjct: 143 ALPEAAVGLLPCAGGTQALPWLVGEGWAKRMILCNERVDAETALRIGLVEQVVDSGE 199 >2DUB-A nrPDB Length = 261 Score = 110 bits (275), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 76/199 (38%), Positives = 106/199 (53%), Gaps = 10/199 (5%) Query: 18 VAVITLINP-PVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGFGEM 76 V +I L P +N+L ++ L E V AIV+TG + F+ G DI EM Sbjct: 18 VGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIK---EM 74 Query: 77 QKGNVKEPKAG-YIS-IDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAAQ 134 Q ++ +G ++S D IT + +KP +AA++G ALGGG ELAM C + AQ Sbjct: 75 QNRTFQDCYSGKFLSHWDHITRI----KKPVIAAVNGYALGGGCELAMMCDIIYAGEKAQ 130 Query: 135 LGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAELV 194 G PE+ LG IPG GGTQRL R VG + A+EM+LT + A++ GL+ + P LV Sbjct: 131 FGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETLV 190 Query: 195 TTARRWALDIVGRRKPWVS 213 A + A I K V+ Sbjct: 191 EEAIQCAEKIANNSKIIVA 209 >4OM8-A nrPDB Length = 309 Score = 101 bits (252), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 90/324 (27%), Positives = 154/324 (47%), Gaps = 44/324 (13%) Query: 312 IKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQE 371 I+ +AIIG G MG G+A L V+ +V A I R ++ L S+++ Sbjct: 2 IRNIAIIGLGTMGPGMAARLARGGLQVVAYDVAP----AAIERARSML-------SVAET 50 Query: 372 KFEKT-MSLLKGSLDYESFRD--------VDMVIEAVIENISLKQQIFADLEKYCPQHCI 422 + ++L + F D D+VIE V ENIS+K ++ ++ Q I Sbjct: 51 VLDALGIALPSAGVGTVRFTDDIGDAVSGADLVIENVPENISIKADVYRTIDGLIGQDTI 110 Query: 423 LASNTSTIDLNKIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDVGKK 482 +AS+TS I + K+ +R+VG H+ +P HI+P++E++ T+ Q + + D+ + Sbjct: 111 VASDTSGIPITKLQAHISYPERMVGMHWSNPPHIIPMIEVIAGEKTAPQTVATIRDLIRS 170 Query: 483 IKKTPVVV-GNCTGFAVNRMFFPYTQAAMFLVECGA-DPYLIDRAISKFGM-----PMGP 535 I PVVV + GF NR+ + + A+ LVE G DP +D +S +G+ +GP Sbjct: 171 IGLLPVVVKKDVPGFVENRVLYALLREAVDLVERGVIDPEDLDTCVS-WGIGYKIAVIGP 229 Query: 536 FRLCDLVGFGVAIATATQFIENFSERTYKSMIIPLMQEDKRA---GEATRKGFYLYDDKR 592 L D+ G + + ++ + S R + P++ E A G + +G + Y Sbjct: 230 MALLDMAGLDIYKSVSSFLNADLSNR---DDVAPMVLEKTSASKFGIKSGEGMFCY---- 282 Query: 593 KAKPDPELKKYI--EKARSISGVK 614 PE K + E+AR + V+ Sbjct: 283 ----TPEQTKALQAERARKLVAVR 302 >2HW5-A nrPDB Length = 286 Score = 101 bits (251), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 62/162 (38%), Positives = 85/162 (52%), Gaps = 5/162 (3%) Query: 52 VKAIVITGAKGRFSGGFDISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDG 111 V AIV+TG F+ G DI EMQ + ++ + D L +KP +AA++G Sbjct: 78 VGAIVLTGGDKAFAAGADIK---EMQNLSFQDCYSSKFLKHW--DHLTQVKKPVIAAVNG 132 Query: 112 LALGGGLELAMACHARISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSK 171 A GGG ELAM C + AQ PE+ +G IPG GGTQRL R VG + A+EM+LT Sbjct: 133 YAFGGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGD 192 Query: 172 PVKAEEGHSLGLIDAVVPPAELVTTARRWALDIVGRRKPWVS 213 + A++ GL+ + P LV A + A I K V+ Sbjct: 193 RISAQDAKQAGLVSKICPVETLVEEAIQCAEKIASNSKIVVA 234 >4FZW-A nrPDB Length = 258 Score = 97.8 bits (242), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 61/176 (34%), Positives = 94/176 (53%), Gaps = 12/176 (6%) Query: 18 VAVITLINPPV-NSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGFGEM 76 V ++TL P N+L+ +L L + E A + + VITG F+ G D++ E Sbjct: 15 VLLLTLNRPAARNALNNALLMQLVNELEAAATDTSISVCVITGNARFFAAGADLNEMAEK 74 Query: 77 QKG---NVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAA 133 N P+ + L+A KP +AA++G ALG G ELA+ C ++ A Sbjct: 75 DLAATLNDTRPQ--------LWARLQAFNKPLIAAVNGYALGAGCELALLCDVVVAGENA 126 Query: 134 QLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVP 189 + GLPE+ LG++PG GGTQRL R VG + A +M+L+ + + A++ GL+ V P Sbjct: 127 RFGLPEITLGIMPGAGGTQRLIRSVGKSLASKMVLSGESITAQQAQQAGLVSDVFP 182 >4DYD-A nrPDB Length = 283 Score = 95.9 bits (237), Expect = 6e-20, Method: Compositional matrix adjust. Identities = 75/283 (26%), Positives = 135/283 (47%), Gaps = 9/283 (3%) Query: 312 IKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVK--ANLQSRVRKGSMS 369 I V ++G G++GS IA + V ++N L+A R + A + + G+ + Sbjct: 4 ITNVTVLGTGVLGSQIAFQTAFHGFAVTAYDINTDALDAAKKRFEGLAAVYEKEVAGA-A 62 Query: 370 QEKFEKTMSLLKGSLDY-ESFRDVDMVIEAVIENISLKQQIFADLEKYCPQHCILASNTS 428 +K + ++ S D ++ +D D+VIEAV E++ LK+ I+ L + P I A+N+S Sbjct: 63 DGAAQKALGGIRYSDDLAQAVKDADLVIEAVPESLDLKRDIYTKLGELAPAKTIFATNSS 122 Query: 429 TIDLNKIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDVGKKIKKTPV 488 T+ + + T D+ + HF + + E++ T T +V +++ I P+ Sbjct: 123 TLLPSDLVGYTGRGDKFLALHFANHVWVNNTAEVMGTTKTDPEVYQQVVEFASAIGMVPI 182 Query: 489 VV-GNCTGFAVNRMFFPYTQAAM-FLVECGADPYLIDRAIS-KFGMPMGPFRLCDLVGFG 545 + G+ +N + P AA LV+ ADP ID+ G P GPF + D+VG Sbjct: 183 ELKKEKAGYVLNSLLVPLLDAAAELLVDGIADPETIDKTWRIGTGAPKGPFEIFDIVGLT 242 Query: 546 VAIATATQFIENFSERTYKSMIIPLMQEDKRAGEATRKGFYLY 588 A ++ + +R + + + + + G AT +GFY Y Sbjct: 243 TAYNISS--VSGPKQREFAAYLKENYIDKGKLGLATGEGFYRY 283 >2PPY-A nrPDB Length = 265 Score = 95.5 bits (236), Expect = 8e-20, Method: Compositional matrix adjust. Identities = 68/216 (31%), Positives = 108/216 (50%), Gaps = 11/216 (5%) Query: 5 TKGKTVMEVGGDGVAVITLINPPVNSLSFDVLYNLKSNYEEALSRNDVKA-IVITGAKGR 63 TK + + DG+A I L NS + + ++ D+K IV++ Sbjct: 6 TKKQYLTVFKEDGIAEIHLHINKSNSYDLEFYKEFNAAIDDIRFDPDIKVVIVMSDVPKF 65 Query: 64 FSGGFDISGFGEMQKGNVKEPKAGYISIDIITDLLEA-ARKPSV--AAIDGLALGGGLEL 120 FS G DI+ +P+ + L+ AR P V A ++G +GGGLE+ Sbjct: 66 FSAGADINFL------RSADPRFKTQFCLFCNETLDKIARSPQVYIACLEGHTVGGGLEM 119 Query: 121 AMACHAR-ISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGH 179 A+AC R + A ++GLPE+ LGV+ G GGTQRL RL+G ++AL+M +T + + +E Sbjct: 120 ALACDLRFMGDEAGKIGLPEVSLGVLAGTGGTQRLARLIGYSRALDMNITGETITPQEAL 179 Query: 180 SLGLIDAVVPPAELVTTARRWALDIVGRRKPWVSSV 215 +GL++ V P AE R +A + VS++ Sbjct: 180 EIGLVNRVFPQAETRERTREYARKLANSATYAVSNI 215 >4JWV-A nrPDB Length = 278 Score = 90.9 bits (224), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 65/187 (34%), Positives = 100/187 (53%), Gaps = 9/187 (4%) Query: 18 VAVITLINPP-VNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGR--FSGGFDISGFG 74 VA + L P +N+++ ++ L + E + +D+ A+V++ A+G F G D+SG Sbjct: 34 VAHVRLNRPQGLNAITQEMDDLLLDAWTEVNANSDIWAVVLS-AEGEKAFCIGADVSGGA 92 Query: 75 EMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAAQ 134 E + I ++T +KP VAA+ G +GGG ELAM ++A AQ Sbjct: 93 ERKTRMALGGGLTGIGGPLVT-----CKKPMVAAVQGFCVGGGFELAMCADIIVAADTAQ 147 Query: 135 LGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAELV 194 GLPE ++G+I G R R + AL++ILT + +KA+E GL++ VVP AEL Sbjct: 148 FGLPETKVGIIGECGVVHRAMRQLPYHIALQLILTGERIKADEARHYGLVNEVVPFAELE 207 Query: 195 TTARRWA 201 A RWA Sbjct: 208 EAALRWA 214 >3HIN-A nrPDB Length = 275 Score = 85.9 bits (211), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 47/129 (36%), Positives = 74/129 (57%), Gaps = 3/129 (2%) Query: 50 NDVKAIVITGAKGRFSGGFDISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAI 109 + ++A+VI G FS G D+S E+++ + E + + D ++ R P +AA+ Sbjct: 57 DQIRAVVIHGIGDHFSAGLDLS---ELRERDATEGLVHSQTWHRVFDKIQYCRVPVIAAL 113 Query: 110 DGLALGGGLELAMACHARISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILT 169 G +GGGLELA A H R++ +A LPE G+ G GG+ RLPRL+G+ + +M+LT Sbjct: 114 KGAVIGGGLELACAAHIRVAEASAYYALPEGSRGIFVGGGGSVRLPRLIGVARMADMMLT 173 Query: 170 SKPVKAEEG 178 + A EG Sbjct: 174 GRVYSAAEG 182 >4JSB-A nrPDB Length = 296 Score = 81.3 bits (199), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 68/216 (31%), Positives = 101/216 (46%), Gaps = 29/216 (13%) Query: 3 SRTKGKTVMEVGGDG--------VAVITLINPPVNSLSFDVLYNLKSNYEEALSRNDVKA 54 ++TK T E+ G VA ITL P + ++ + L + V+ Sbjct: 23 AQTKAPTAEELAAAGLTLTIDGEVARITLSRPHRRNAMTGRMWTELARIGHTLPQA-VRI 81 Query: 55 IVITGAKGRFSGGFDISGFGEMQKGNV-----------KEPKAGYISIDIITDLLEA--- 100 +VITG FS G D+ F Q G V ++P + +I E Sbjct: 82 VVITGEGPTFSSGIDLDMF---QAGKVDGEPTPFTLLARDPNSTAALDQVIASYQEGFLW 138 Query: 101 ---ARKPSVAAIDGLALGGGLELAMACHARISAPAAQLGLPELQLGVIPGFGGTQRLPRL 157 A S+AA+ G A+G G +LA++C RI + AQL + E LG++P GTQ L L Sbjct: 139 LRRADIVSIAAVRGHAIGAGFQLALSCDIRILSDTAQLCMKEPALGLVPDLTGTQPLVEL 198 Query: 158 VGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAEL 193 VG+ +A+E+ LT++ + A E L L + VV AEL Sbjct: 199 VGVNRAIELCLTARTIDAAEAAQLRLAERVVADAEL 234 >4JCS-A nrPDB Length = 286 Score = 80.5 bits (197), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 54/182 (29%), Positives = 91/182 (50%), Gaps = 6/182 (3%) Query: 25 NPPVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGFGE-MQKGNVKE 83 NP L D++ L+ ++A D++ +V+T G F G ++ + + G Sbjct: 46 NPFDAELRADLMTVLERVRDDA----DIRVLVLTSHPGSFCAGGNLHVLRDNLDSGPAYW 101 Query: 84 PKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAAQLGLPELQLG 143 + + I D+L R P +AA+DG A G G L++ +++P A+ + L+LG Sbjct: 102 QQRIKTGLRFIHDMLNLGR-PVIAAVDGPAFGAGFALSLTADIVLASPRARFSMAYLRLG 160 Query: 144 VIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAELVTTARRWALD 203 ++P G LPR VGL +A E++ +++ + AEE H LGL+ V L AR A Sbjct: 161 LVPDLGALYLLPRAVGLQRAKELMFSTRELDAEEAHRLGLVMEVHESEALEQRAREIAES 220 Query: 204 IV 205 +V Sbjct: 221 LV 222 >4IZC-A nrPDB Length = 275 Score = 78.2 bits (191), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 59/183 (32%), Positives = 90/183 (49%), Gaps = 21/183 (11%) Query: 11 MEVGGDGVAVITLINPPV-NSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFD 69 +++ +GV V+TL P N+L + L + + A R V+A+V+TGA F G D Sbjct: 14 LDLRDNGVCVVTLNRPDKRNALDVATIEELVTFFSTA-HRKGVRAVVLTGAGDHFCAGLD 72 Query: 70 ISGFGEMQKGNVKEPKAGYISIDIITDLL---EAARK------PSVAAIDGLALGGGLEL 120 + V+ KA + D + L EA K P +AA+ G +GGGL L Sbjct: 73 L----------VEHWKADRSADDFMHVCLRWHEAFNKMEYGGVPIIAALRGAVVGGGLAL 122 Query: 121 AMACHARISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHS 180 A A H R+ + LPE Q G+ G G T R+ ++G + ++MILT + + +E Sbjct: 123 ASAAHLRVMDQSTYFALPEGQRGIFTGGGATIRVSDMIGKYRMIDMILTGRVYQGQEAAD 182 Query: 181 LGL 183 LGL Sbjct: 183 LGL 185 >2IEX-A nrPDB Length = 272 Score = 75.5 bits (184), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 57/194 (29%), Positives = 96/194 (49%), Gaps = 8/194 (4%) Query: 16 DGVAVITLINPPV-NSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGR-FSGGFD--IS 71 +G+A IT+ P V N+ + + + +A +++ I++TGA G+ F G D + Sbjct: 20 NGIAKITINRPEVHNAFRPKTVNEMIDAFTKARDDSNIGVIILTGAGGKAFCSGGDQKVR 79 Query: 72 GFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAP 131 G G G V E + +++ + L+ KP +A + G A+GGG L + C I+A Sbjct: 80 GHG----GYVGEDEIPRLNVLDLQRLIRVIPKPVIAMVAGYAIGGGHVLHVVCDLTIAAD 135 Query: 132 AAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPA 191 A G ++G G G L R+VG KA E+ + A+E +GL++ VVP Sbjct: 136 NAIFGQTGPKVGSFDGGYGAGYLARIVGHKKAREIWYLCRQYTAQEALEMGLVNKVVPLE 195 Query: 192 ELVTTARRWALDIV 205 +L +WA +I+ Sbjct: 196 QLEEETVKWAQEIL 209 >1NZY-B nrPDB Length = 269 Score = 70.9 bits (172), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 57/187 (30%), Positives = 92/187 (49%), Gaps = 7/187 (3%) Query: 16 DGVAVITLINP-PVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGFG 74 DGVA IT+ P N+LS + + A + V A++ITGA+ F GF + Sbjct: 11 DGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLREI- 69 Query: 75 EMQKG--NVKEP--KAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISA 130 + KG V++ A +I ++ R P +AAI+G+A GGGL +++A I A Sbjct: 70 PLDKGVAGVRDHFRIAALWWHQMIHKIIRVKR-PVLAAINGVAAGGGLGISLASDMAICA 128 Query: 131 PAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPP 190 +A+ +G+ + L R+VG+ +A+E++LT + + EE GL+ V P Sbjct: 129 DSAKFVCAWHTIGIGNDTATSYSLARIVGMRRAMELMLTDRTLYPEEAKDWGLVSRVYPK 188 Query: 191 AELVTTA 197 E A Sbjct: 189 DEFREVA 195 >5YLO-A nrPDB Length = 271 Score = 70.5 bits (171), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 50/179 (27%), Positives = 81/179 (45%), Gaps = 1/179 (0%) Query: 17 GVAVITLINPPV-NSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGFGE 75 G+A + L P N+L L L + V+A+V+ G+ F G D++ + Sbjct: 14 GIAWLVLNRPQQRNALDIPTLEALHVRLDACERDPAVRAVVLGGSGRSFCAGADLAEWAA 73 Query: 76 MQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAAQL 135 + E + + L A KP+VAA++G A+G G++LA+ C RI+A +A+ Sbjct: 74 AEARGELESYGWTEAAHALMGRLHALDKPTVAAVNGSAVGAGMDLALCCDFRIAAASARF 133 Query: 136 GLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAELV 194 + P G + LPRL+G A ++ + AE GL+ VV LV Sbjct: 134 KAGYTGMAYCPDAGASWHLPRLLGSEAAKRLLFLDEAWSAERALGAGLVGEVVADEHLV 192 >3T88-A nrPDB Length = 289 Score = 70.1 bits (170), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 52/192 (27%), Positives = 90/192 (46%), Gaps = 3/192 (1%) Query: 16 DGVAVITLINPPV-NSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGR-FSGGFDISGF 73 DG+A IT+ P V N+ + + +A +++ I++TGA + F G D Sbjct: 36 DGIAKITINRPQVRNAFRPLTVKEMIQALADARYDDNIGVIILTGAGDKAFCSGGDQKVR 95 Query: 74 GEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAA 133 G+ G + ++++ + KP VA + G ++GGG L M C I+A A Sbjct: 96 GDY-GGYKDDSGVHHLNVLDFQRQIRTCPKPVVAMVAGYSIGGGHVLHMMCDLTIAADNA 154 Query: 134 QLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAEL 193 G ++G G G + R+VG KA E+ + A++ +GL++ VVP A+L Sbjct: 155 IFGQTGPKVGSFDGGWGASYMARIVGQKKAREIWFLCRQYDAKQALDMGLVNTVVPLADL 214 Query: 194 VTTARRWALDIV 205 RW +++ Sbjct: 215 EKETVRWCREML 226 >2VSU-C nrPDB Length = 275 Score = 68.6 bits (166), Expect = 9e-12, Method: Compositional matrix adjust. Identities = 55/198 (27%), Positives = 92/198 (46%), Gaps = 17/198 (8%) Query: 6 KGKTVMEVGGDGVAVITL--------INPPVNSLSFDVLYNLKSNYEEALSRNDVKAIVI 57 + KTV DG+A + L ++P +N DVL L+ + + +V+ Sbjct: 7 RWKTVKVEIEDGIAFVILNRPEKRNAMSPTLNREMIDVLETLEQDPAAGV-------LVL 59 Query: 58 TGAKGRFSGGFDISG-FGEMQKG-NVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALG 115 TGA ++ G D+ F E+ G + + K + LL KP++A ++G G Sbjct: 60 TGAGEAWTAGMDLKEYFREVDAGPEILQEKIRREASQWQWKLLRMYAKPTIAMVNGWCFG 119 Query: 116 GGLELAMACHARISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKA 175 GG +AC I A A GL E+ G+ PG ++ + VG ++L I+T K Sbjct: 120 GGFAPLVACDLAICADEATFGLSEINWGIPPGNLVSKAMADTVGHRQSLYYIMTGKTFGG 179 Query: 176 EEGHSLGLIDAVVPPAEL 193 ++ +GL++ VP A+L Sbjct: 180 QKAAEMGLVNESVPLAQL 197 >4ZU2-A nrPDB Length = 272 Score = 68.2 bits (165), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 59/207 (28%), Positives = 94/207 (45%), Gaps = 8/207 (3%) Query: 16 DGVAVITLINPPV-NSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGFG 74 +GV ITL P N++S ++ L++ V+A+V+ GA G F G DI Sbjct: 15 EGVLRITLNRPQSRNAMSLAMVGELRAVLAAVRDDRSVRALVLRGADGHFCAGGDIKDMA 74 Query: 75 EMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAAQ 134 + + + + + + +AA + VA ++G LGGG LA I+A AQ Sbjct: 75 GARAAGAEAYRTLNRAFGSLLEEAQAAPQLLVALVEGAVLGGGFGLACVSDVAIAAADAQ 134 Query: 135 LGLPELQLGVIPGFGGTQRLP---RLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPA 191 GLPE LG++P Q P R +GLT+A + LT+ E LGL+ A Sbjct: 135 FGLPETSLGILP----AQIAPFVVRRIGLTQARRLALTAARFDGREALRLGLVHFCEADA 190 Query: 192 ELVTTARRWALDIVGRRKPWVSSVSKT 218 + + L+ + R P ++ +K Sbjct: 191 DALEQRLEETLEQLRRCAPNANAATKA 217 >3F3S-A nrPDB Length = 313 Score = 68.2 bits (165), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 61/225 (27%), Positives = 110/225 (48%), Gaps = 11/225 (4%) Query: 315 VAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANL----QSRVRKGSMSQ 370 V I+G G++G A + V L ++ ++ + + ++ + Q+ KGS+S Sbjct: 6 VVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQAGSLKGSLS- 64 Query: 371 EKFEKTMSLLKGSLDYESFRDVDMVI-EAVIENISLKQQIFADLEKYCPQHCILASNTST 429 E+ +SL+ G + + + M I E V E++ LK++IFA L+ IL+S+TS Sbjct: 65 --VEEQLSLISGCPNIQEAVEGAMHIQECVPEDLELKKKIFAQLDSIIDDRVILSSSTSC 122 Query: 430 IDLNKIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDVGKKIKKTPV- 488 + +K+ + + AH +P + +PL+E+V T+ + + KKI + P+ Sbjct: 123 LMPSKLFAGLVHVKQCIVAHPVNPPYYIPLVELVPHPETAPTTVDRTHALMKKIGQCPMR 182 Query: 489 VVGNCTGFAVNRMFFPYTQAAMFLVECG-ADPYLIDRAISK-FGM 531 V GF +NR+ + A LVE G P +D +S+ GM Sbjct: 183 VQKEVAGFVLNRLQYAIISEAWRLVEEGIVSPSDLDLVMSEGLGM 227 >1EF9-A nrPDB Length = 261 Score = 67.0 bits (162), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 54/200 (27%), Positives = 97/200 (48%), Gaps = 10/200 (5%) Query: 47 LSRNDVKAIVITGAKGR--FSGGFDISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKP 104 L+R +++ I++ G FS G DI E+ G ++P + + IT +++ KP Sbjct: 43 LNRPEIRCIILRAPSGSKVFSAGHDIH---ELPSGG-RDPLSYDDPLRQITRMIQKFPKP 98 Query: 105 SVAAIDGLALGGGLELAMACHARISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKAL 164 ++ ++G GG E+ M+ I+A + + + LGV G L R G Sbjct: 99 IISMVEGSVWGGAFEMIMSSDLIIAASTSTFSMTPVNLGVPYNLVGIHNLTRDAGFHIVK 158 Query: 165 EMILTSKPVKAEEGHSLGLIDAVVPPAELVTTARRWALDIVGRRKPWVSSVSKTDKLPPL 224 E+I T+ P+ A+ ++G+++ VV EL + A I + P +V K ++L L Sbjct: 159 ELIFTASPITAQRALAVGILNHVVEVEELEDFTLQMAHHI-SEKAPLAIAVIK-EELRVL 216 Query: 225 GEAREILT--FAKAQTLKRA 242 GEA + + F + Q ++RA Sbjct: 217 GEAHTMNSDEFERIQGMRRA 236 >1XX4-A nrPDB Length = 261 Score = 66.2 bits (160), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 51/188 (27%), Positives = 87/188 (46%), Gaps = 6/188 (3%) Query: 14 GGDGVAVITLINPPVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAK-GRFSGGFDISG 72 G G+AV+ NPPVNSLS + L + E+ + ++ +++T + G FS G D+ Sbjct: 12 GEAGIAVMKFKNPPVNSLSLEFLTEFVISLEKLENDKSIRGVILTSERPGIFSAGLDLM- 70 Query: 73 FGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPA 132 EM N + ++ + L + ++AI+G + GG +A+ C RI A Sbjct: 71 --EMYGRNPAHYAEYWKAVQELWLRLYLSNLTLISAINGASPAGGCLMALTCDYRIMADN 128 Query: 133 AQ--LGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPP 190 ++ +GL E LG++ F +G A + E +GL+D VVP Sbjct: 129 SKYTIGLNESLLGIVAPFWLKDNYVNTIGHRAAERALQLGTLFPPAEALKVGLVDEVVPE 188 Query: 191 AELVTTAR 198 ++ + AR Sbjct: 189 DQVHSKAR 196 >4EML-A nrPDB Length = 275 Score = 66.2 bits (160), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 53/198 (26%), Positives = 91/198 (45%), Gaps = 9/198 (4%) Query: 17 GVAVITLINP-PVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGA------KGRFSGGFD 69 G+A I + P N+ ++ L + A N + +++TGA K F G D Sbjct: 19 GIAKIVINRPHKRNAFRPQTVFELYDAFCNAREDNRIGVVLLTGAGPHSDGKYAFCSGGD 78 Query: 70 ISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARIS 129 S GE G + + +++ + L+ + K +A + G A+GGG L + C I+ Sbjct: 79 QSVRGE--GGYIDDQGTPRLNVLDLQRLIRSMPKVVIALVAGYAIGGGHVLHLVCDLTIA 136 Query: 130 APAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVP 189 A A G ++G G G+ L R+VG KA E+ + A+E +G+++ VVP Sbjct: 137 ADNAIFGQTGPKVGSFDGGFGSSYLARIVGQKKAREIWYLCRQYSAQEAERMGMVNTVVP 196 Query: 190 PAELVTTARRWALDIVGR 207 L +WA +I+ + Sbjct: 197 VDRLEEEGIQWAKEILSK 214 >2UZF-A nrPDB Length = 273 Score = 65.9 bits (159), Expect = 7e-11, Method: Compositional matrix adjust. Identities = 52/192 (27%), Positives = 89/192 (46%), Gaps = 4/192 (2%) Query: 16 DGVAVITLINPPV-NSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKG-RFSGGFDISGF 73 +G+A +T+ P V N+ + + + + A +V IV+TG F G D Sbjct: 21 EGIAKVTINRPEVRNAFTPKTVAEMIDAFSRARDDQNVSVIVLTGEGDLAFCSGGDQKKR 80 Query: 74 GEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAA 133 G G V E + +++ + L+ KP +A + G A+GGG L + C I+A A Sbjct: 81 G--HGGYVGEDQIPRLNVLDLQRLIRIIPKPVIAMVKGYAVGGGNVLNVVCDLTIAADNA 138 Query: 134 QLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAEL 193 G ++G G+ L R+VG KA E+ + A+E +GL++ VVP ++ Sbjct: 139 IFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNAQEALDMGLVNTVVPLEKV 198 Query: 194 VTTARRWALDIV 205 +W +I+ Sbjct: 199 EDETVQWCKEIM 210 >2A81-A nrPDB Length = 250 Score = 65.5 bits (158), Expect = 9e-11, Method: Compositional matrix adjust. Identities = 58/193 (30%), Positives = 92/193 (47%), Gaps = 11/193 (5%) Query: 10 VMEVGGDGVAVITLINP-PVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGR-FSGG 67 V E D V VITL +P N S + ++K A + + V+A+V+ G R FS G Sbjct: 2 VFEENSDEVRVITLDHPNKHNPFSRTLETSVKDALARANADDSVRAVVVYGGAERSFSAG 61 Query: 68 FDISGFGEMQKGNVKEPKAGYISIDIITDLLEAA---RKPSVAAIDGLALGGGLELAMAC 124 D F E+++ + E +I D + DL +A KP++AA+DG A+G G + A+ Sbjct: 62 GD---FNEVKQLSRSEDIEEWI--DRVIDLYQAVLNVNKPTIAAVDGYAIGMGFQFALMF 116 Query: 125 HARISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLI 184 R+ A A +PEL+ G+ G L G + E+I + + A L+ Sbjct: 117 DQRLMASTANFVMPELKHGIGCSVGAA-ILGFTHGFSTMQEIIYQCQSLDAPRCVDYRLV 175 Query: 185 DAVVPPAELVTTA 197 + VV + L+ A Sbjct: 176 NQVVESSALLDAA 188 >3OME-A nrPDB Length = 282 Score = 65.1 bits (157), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 60/204 (29%), Positives = 91/204 (44%), Gaps = 29/204 (14%) Query: 16 DGVAVITLINP-PVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGFG 74 D +A ITL P N+ + ++L L + + A N+VK I++ FS G D+ G G Sbjct: 31 DSIATITLNRPEAANAQNPELLDELDAAWTRAAEDNEVKVIILRANGKHFSAGHDLRGGG 90 Query: 75 EMQKGNVKEPKAGYISIDIITDLLEAAR------------KPSVAAIDGLALGGGLELAM 122 E+ + IS++ I EA R KPS+AA+ G + GGL L Sbjct: 91 EVPE---------KISLEFIIQH-EARRYLDYTLRWRNVPKPSIAAVQGRCISGGLLLCW 140 Query: 123 ACHARISAPAAQLGLPELQLGV--IPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHS 180 C +++ A P +G+ + G T L G KA E++ T + + AEE Sbjct: 141 PCDLILASDDALFSDPVALMGIGGVEYHGHTWEL----GPRKAKEILFTGRALTAEEAER 196 Query: 181 LGLIDAVVPPAELVTTARRWALDI 204 G+++ VV EL R A I Sbjct: 197 TGMVNRVVARDELDAQTRELAEQI 220 >3BPT-A nrPDB Length = 363 Score = 62.4 bits (150), Expect = 7e-10, Method: Compositional matrix adjust. Identities = 41/144 (28%), Positives = 71/144 (49%), Gaps = 2/144 (1%) Query: 18 VAVITLINPP-VNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGR-FSGGFDISGFGE 75 VITL P +N+L+ +++ + ++ + I+I GA G+ F G DI E Sbjct: 16 TGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISE 75 Query: 76 MQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAAQL 135 +K K + ++ + + + +KP VA I G+ +GGG+ L++ R++ Sbjct: 76 AEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLF 135 Query: 136 GLPELQLGVIPGFGGTQRLPRLVG 159 +PE +G+ P GG LPRL G Sbjct: 136 AMPETAIGLFPDVGGGYFLPRLQG 159 >3ADO-A nrPDB Length = 319 Score = 62.0 bits (149), Expect = 9e-10, Method: Compositional matrix adjust. Identities = 65/254 (25%), Positives = 119/254 (46%), Gaps = 13/254 (5%) Query: 315 VAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQE-KF 373 V I+G GL+G A + V L ++ + + + ++ ++S + GS+ Sbjct: 9 VLIVGSGLVGRSWAMLFASGGFRVKLYDIEPRQITGALENIRKEMKSLQQSGSLKGSLSA 68 Query: 374 EKTMSLLKGSLDY-ESFRDVDMVIEAVIENISLKQQIFADLEKYCPQHCILASNTSTIDL 432 E+ +SL+ + E+ V + E V EN+ LK++IFA L+ +L+S++S + Sbjct: 69 EEQLSLISSCTNLAEAVEGVVHIQECVPENLDLKRKIFAQLDSIVDDRVVLSSSSSCLLP 128 Query: 433 NKIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDVGKKIKKTPV-VVG 491 +K+ + + AH +P + +PL+E+V TS + + +KI ++PV V+ Sbjct: 129 SKLFTGLAHVKQCIVAHPVNPPYYIPLVELVPHPETSPATVDRTHALMRKIGQSPVRVLK 188 Query: 492 NCTGFAVNRMFFPYTQAAMFLVECG-ADPYLIDRAISK-FGMP---MGPFRLCDLVGFGV 546 GF +NR+ + A LVE G P +D +S GM +GP L G+ Sbjct: 189 EIDGFVLNRLQYAIISEAWRLVEEGIVSPSDLDLVMSDGLGMRYAFIGPLETMHLNAEGM 248 Query: 547 AIATATQFIENFSE 560 + + +SE Sbjct: 249 -----LSYCDRYSE 257 >3M6N-A nrPDB Length = 305 Score = 61.2 bits (147), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 32/92 (34%), Positives = 50/92 (54%) Query: 101 ARKPSVAAIDGLALGGGLELAMACHARISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGL 160 AR S+A + G ALGGG E A++CH I+ +GLPE+ + PG G + + + Sbjct: 139 ARAHSIALVQGNALGGGFEAALSCHTIIAEEGVMMGLPEVLFDLFPGMGAYSFMCQRISA 198 Query: 161 TKALEMILTSKPVKAEEGHSLGLIDAVVPPAE 192 A +++L AE+ +GL+D VVP + Sbjct: 199 HLAQKIMLEGNLYSAEQLLGMGLVDRVVPRGQ 230 >5KJP-A nrPDB Length = 265 Score = 61.2 bits (147), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 51/176 (28%), Positives = 85/176 (48%), Gaps = 9/176 (5%) Query: 16 DGVAVITLINPPV-NSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGFG 74 D + +IT+ P N+++ V L ++ + ++TG G F G D+ F Sbjct: 23 DRILIITINRPKAKNAVNAAVSRGLADAMDQLDGDAGLSVAILTGGGGSFCAGMDLKAFA 82 Query: 75 EMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAAQ 134 + V+ G+ KP +AA++G AL GG ELA+A ++A + Sbjct: 83 RGENVVVEGRGLGFTE--------RPPTKPLIAAVEGYALAGGTELALAADLIVAARDSA 134 Query: 135 LGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPP 190 G+PE++ G++ G GG RLP + A+E+ LT + AE H LGL++ + P Sbjct: 135 FGIPEVKRGLVAGGGGLLRLPERIPYAIAMELALTGDNLPAERAHELGLVNVLAEP 190 >3HE2-A nrPDB Length = 264 Score = 60.5 bits (145), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 60/211 (28%), Positives = 99/211 (46%), Gaps = 22/211 (10%) Query: 1 MDSRTKGKTVMEVG---GDGVAVITLINPPV-NSLSFDVLYNLKSNYEEALSRNDVKAIV 56 ++++T+G M +G + V I L P N+L+ ++ L +A +AIV Sbjct: 12 LEAQTQGPGSM-IGITQAEAVLTIELQRPERRNALNSQLVEELTQAIRKA-GDGSARAIV 69 Query: 57 ITGAKGRFSGGFDISG--FGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLAL 114 +TG F G D+SG F + E + ++A+ P V AI+G A+ Sbjct: 70 LTGQGTAFCAGADLSGDAFAADYPDRLIE----------LHKAMDASPMPVVGAINGPAI 119 Query: 115 GGGLELAMACHARISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVK 174 G GL+LAM C R+ AP A P + G+ +RL LVG +A M+L+++ + Sbjct: 120 GAGLQLAMQCDLRVVAPDAFFQFPTSKYGLALDNWSIRRLSSLVGHGRARAMLLSAEKLT 179 Query: 175 AEEGHSLGLIDAVVPPAELVTTARRWALDIV 205 AE G+ + + A+ A+ WA +I Sbjct: 180 AEIALHTGMANRIGTLAD----AQAWAAEIA 206 >6OJM-A nrPDB Length = 286 Score = 60.5 bits (145), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 50/199 (25%), Positives = 87/199 (43%), Gaps = 7/199 (3%) Query: 16 DGVAVITLINPPV-NSLSFDVLYNLKSNYEEALSRNDVKAIVITG-AKGRFSGGFDISGF 73 +GVA I P + N+ L + +A + ++++G GG+ Sbjct: 27 NGVARIAFNRPEIRNAFRPKTTSELYDAFYDAYEDPSIGVVLLSGEGPSPKDGGWAFCSG 86 Query: 74 GEM----QKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARI- 128 G+ +G V E ++I + L+ K +A + G A+GGG L + C + Sbjct: 87 GDQKARGHQGYVGEDGRHRLNILEVQRLIRFMPKVVIAVVPGWAVGGGHSLHVVCDLTLA 146 Query: 129 SAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVV 188 S A + + G G+ L ++VG KA E+ + A+E +G+++ VV Sbjct: 147 SKEHAIFKQTDADVTSFDGGYGSAYLAKMVGQKKAREIFFLGRNYSAQEAFEMGMVNKVV 206 Query: 189 PPAELVTTARRWALDIVGR 207 P AEL TA WA +I+ + Sbjct: 207 PHAELEDTAYEWAQEILAK 225 >5MRE-88 nrPDB Length = 457 Score = 60.1 bits (144), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 55/199 (27%), Positives = 91/199 (45%), Gaps = 21/199 (10%) Query: 16 DGVAVITLINPP-VNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGR---FSGGFDIS 71 D VITL P +N+L+ ++ ++ E +++D +VI + R F G D++ Sbjct: 10 DTARVITLNRPKKLNALNAEMSESMFKTLNE-YAKSDTTNLVILKSSNRPRSFCAGGDVA 68 Query: 72 -----GFGEMQKGNVKEPKAGY-ISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACH 125 F + ++K Y ++ I T L KP V +DG+ +GGG+ L++ Sbjct: 69 TVAIFNFNKEFAKSIKFFTDEYSLNFQIATYL-----KPIVTFMDGITMGGGVGLSIHTP 123 Query: 126 ARISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTK-----ALEMILTSKPVKAEEGHS 180 RI+ + +PE+ +G P G T LPR+V L AL + LT + V + + Sbjct: 124 FRIATENTKWAMPEMDIGFFPDVGSTFALPRIVTLANSNSQMALYLCLTGEVVTGADAYM 183 Query: 181 LGLIDAVVPPAELVTTARR 199 LGL V L +R Sbjct: 184 LGLASHYVSSENLDALQKR 202 >2NP9-A nrPDB Length = 440 Score = 54.7 bits (130), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 34/91 (37%), Positives = 51/91 (56%), Gaps = 1/91 (1%) Query: 103 KPSVAAIDGLALGGGLELAMACHARISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTK 162 KP VAA+DG A+GGG +L + +++ A LP + G+IPG RL R G Sbjct: 285 KPWVAAVDGFAIGGGAQLLLVFDRVLASSDAYFSLPAAKEGIIPG-AANLRLGRFAGPRV 343 Query: 163 ALEMILTSKPVKAEEGHSLGLIDAVVPPAEL 193 + ++IL + + A+E + L+D VV P EL Sbjct: 344 SRQVILEGRRIWAKEPEARLLVDEVVEPDEL 374 >4Q1J-A nrPDB Length = 268 Score = 54.7 bits (130), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 47/193 (24%), Positives = 85/193 (44%), Gaps = 8/193 (4%) Query: 29 NSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGFGEMQKGNVKEPKAGY 88 N+ S ++ +L +E KA+++TG F+ G G +Q+G K Sbjct: 46 NAFSQELTDDLIQAFEYIRQNPKYKAVILTGYDNYFASGGTQEGLLRIQQGLTK------ 99 Query: 89 ISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAAQLGLPELQLGVIPGF 148 + D + L P +AA+ G +GGG + + I + + ++ G PG Sbjct: 100 FTDDNLYSLALDCEIPVIAAMQGHGIGGGFVMGLFADIVILSRESVYTANFMKYGFTPGM 159 Query: 149 GGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAELVTTARRWALDIVGRR 208 G T +P+ +G + A E++L + + + G+ V+P AE++ A A ++ Sbjct: 160 GATFIVPKKLGFSLAQEILLNAGSYRGADLEKRGVPFKVLPRAEVLDYAVELAQELA--E 217 Query: 209 KPWVSSVSKTDKL 221 KP S V+ D L Sbjct: 218 KPRNSLVTLKDHL 230 >3T8B-A nrPDB Length = 334 Score = 53.5 bits (127), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 37/126 (29%), Positives = 58/126 (46%), Gaps = 1/126 (0%) Query: 80 NVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARI-SAPAAQLGLP 138 V +AG + I + L+ K + ++G A GGG L + C + S A+ Sbjct: 145 TVDVARAGRLHILEVQRLIRFMPKVVICLVNGWAAGGGHSLHVVCDLTLASREYARFKQT 204 Query: 139 ELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAELVTTAR 198 + +G G G+ L R VG A E+ + AE+ H +G ++AV AEL T Sbjct: 205 DADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTYTAEQMHQMGAVNAVAEHAELETVGL 264 Query: 199 RWALDI 204 +WA +I Sbjct: 265 QWAAEI 270 >5VE2-A nrPDB Length = 275 Score = 52.4 bits (124), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 45/180 (25%), Positives = 83/180 (46%), Gaps = 8/180 (4%) Query: 24 INPPV--NSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGFGEMQKGNV 81 IN P N+L+ ++ L E + + ++A+++T F+ G D+ F V Sbjct: 40 INRPELKNALNRELYAALADELERSNHDDQIRAVLLTANGDTFTAGNDLDDF----INPV 95 Query: 82 KEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAAQLGLPELQ 141 +E +G S+ + P V A++G A+G GL + + C ++ +A+ P Sbjct: 96 EE--SGTPSVIRFLKAISECETPIVVAVNGPAIGVGLTMLLHCDMVYASKSARFRAPFTH 153 Query: 142 LGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAELVTTARRWA 201 +G++P + LP VG A +++L + + A E S GL+ V LV + + A Sbjct: 154 VGLVPEAASSLLLPLAVGQAWANDLMLAGRILDAREALSAGLVTRVFEDDVLVAESLKIA 213 >4JFC-A nrPDB Length = 281 Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 55/226 (24%), Positives = 108/226 (47%), Gaps = 19/226 (8%) Query: 20 VITLINPPV-NSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGFGEMQK 78 ++TL NP N+L ++ A + +++++VITG F G ++ +Q Sbjct: 37 ILTLSNPEFRNALGPEIYAAGIEALNAAENNPEIRSVVITGEGAVFCAGGNLQ---RLQA 93 Query: 79 GNVKEPKAGYISIDIITDLLEAAR---KPSVAAIDGLALGGGLELAMACHARISAPAAQL 135 + P+ SI+ + + +++ R KP +AA++G A G G LA+AC ++A A Sbjct: 94 NRREAPEVQAQSIEGLHNWIDSIRTYPKPVIAAVEGAAAGAGFSLALACDFVVAASNAVF 153 Query: 136 GLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAELVT 195 + +G+ P GG+ L R + A E+++ + + A+ H LGL++ V + ++ Sbjct: 154 VMSYSTVGLSPDGGGSWSLARSLPRALASELLMGGERISAQRLHDLGLVNKVASAGDALS 213 Query: 196 TARRWALDIVGRRKPWVSSVSKTDKLPPLGEAREILTFAKAQTLKR 241 A R A + R ++S+ +E++ A + TL + Sbjct: 214 EALRMAGQLNARAPNALASI------------KELINEASSNTLSQ 247 >4FZW-C nrPDB Length = 274 Score = 49.7 bits (117), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 55/190 (28%), Positives = 94/190 (49%), Gaps = 8/190 (4%) Query: 17 GVAVITLINPP-VNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGFGE 75 GV +TL P +NS + ++ L ++ + ++ +++TGA F G D++ Sbjct: 24 GVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLNDRNV 83 Query: 76 MQKGNVKEPKAGYISIDIITD----LLEAARKPSVAAIDGLALGGGLELAMACHARISAP 131 G P G +S++ + L KP + A++G+A G G LA+ I+A Sbjct: 84 DPTGPA--PDLG-MSVERFYNPLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAAR 140 Query: 132 AAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPA 191 +A+ + +LG+IP GGT LPR+ G +A+ + L + AE+ H G+I VV Sbjct: 141 SAKFVMAFSKLGLIPDCGGTWLLPRVAGRARAMGLALLGNQLSAEQAHEWGMIWQVVDDE 200 Query: 192 ELVTTARRWA 201 L TA++ A Sbjct: 201 TLADTAQQLA 210 >3LAO-A nrPDB Length = 258 Score = 49.7 bits (117), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 32/99 (32%), Positives = 46/99 (46%) Query: 103 KPSVAAIDGLALGGGLELAMACHARISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTK 162 KP V A+ G G+EL + ++A + E+ G+ P G T R PR G T Sbjct: 106 KPLVVAVQGTCWTAGIELMLNADIAVAARGTRFAHLEVLRGIPPLGGSTVRFPRAAGWTD 165 Query: 163 ALEMILTSKPVKAEEGHSLGLIDAVVPPAELVTTARRWA 201 A+ ILT A+E + L+ VV P E + A +A Sbjct: 166 AMRYILTGDEFDADEALRMRLLTEVVEPGEELARALEYA 204 >4HDT-A nrPDB Length = 353 Score = 48.9 bits (115), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 46/175 (26%), Positives = 80/175 (45%), Gaps = 3/175 (1%) Query: 17 GVAVITLINP-PVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGR-FSGGFDISGFG 74 GV ++TL P +NSL+ ++ + + + V+A+++TGA R G D+ Sbjct: 18 GVGLLTLNRPKAINSLTHGMVTTMAERLAAWENDDSVRAVLLTGAGERGLCAGGDVVAIY 77 Query: 75 EMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAAQ 134 K + E + + + + KP V+ +DG+ +GGG+ + + R+ + Sbjct: 78 HSAKADGAEARRFWFDEYRLNAHIGRYPKPYVSIMDGIVMGGGVGVGAHGNVRVVTDTTK 137 Query: 135 LGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVP 189 + +PE+ +G IP GGT L R G L LT P + +G D VP Sbjct: 138 MAMPEVGIGFIPDVGGTYLLSRAPG-KLGLHAALTGAPFSGADAIVMGFADHYVP 191 >4HC8-A nrPDB Length = 255 Score = 48.9 bits (115), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 56/220 (25%), Positives = 95/220 (43%), Gaps = 23/220 (10%) Query: 16 DGVAVITLINPPVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGF-- 73 D +AVI++ + VN+L + L + + A R+DV A+VITG FSGGFD+ Sbjct: 13 DSIAVISMDDGKVNALGPAMQQALNAAIDNA-DRDDVGALVITGNGRVFSGGFDLKILTS 71 Query: 74 GEMQKGNVKEPKAGYISIDIITDLLEAAR------KPSVAAIDGLALGGGLELAMACHAR 127 GE+Q +ID++ E A KP V A G A+ G L R Sbjct: 72 GEVQP-----------AIDMLRGGFELAYRLLSYPKPVVMACTGHAIAMGAFLLSCGDHR 120 Query: 128 ISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAV 187 ++A A + E+ +G+ + + + + + + +K E + G ID + Sbjct: 121 VAAHAYNIQANEVAIGMTIPYAALEIMKLRLTRSAYQQATGLAKTFFGETALAAGFIDEI 180 Query: 188 VPPAELVTTARRWALDIVGRRKPWVSSV---SKTDKLPPL 224 P +V+ A A + G + ++ S+ D L + Sbjct: 181 ALPEVVVSRAEEAAREFAGLNQHAHAATKLRSRADALTAI 220 >3I47-A nrPDB Length = 268 Score = 48.1 bits (113), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 43/176 (24%), Positives = 84/176 (47%), Gaps = 1/176 (0%) Query: 29 NSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGFGEMQKGNVKEPKAGY 88 N+ +L ++ + A++ +V+ IV+ FS G D++ M +E Sbjct: 26 NAFDNQLLTEMRIRLDSAINDTNVRVIVLKANGKHFSAGADLTWMQSMANFTEEENLEDS 85 Query: 89 ISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAAQLGLPELQLGVIPGF 148 + + + + + KP++A + G A GGG LA AC I++ +A+ E++LG+IP Sbjct: 86 LVLGNLMYSISQSPKPTIAMVQGAAFGGGAGLAAACDIAIASTSARFCFSEVKLGLIPAV 145 Query: 149 GGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAELVTTARRWALDI 204 + + R +G A + ++++ A +SL L+ VP L+ ++A I Sbjct: 146 -ISPYVVRAIGERAAKMLFMSAEVFDATRAYSLNLVQHCVPDDTLLEFTLKYASQI 200 >3HP0-A nrPDB Length = 267 Score = 47.4 bits (111), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 48/177 (27%), Positives = 69/177 (38%), Gaps = 16/177 (9%) Query: 17 GVAVITLINPPVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISG-FGE 75 V IT P N+ D L + V +V+ G F G D + E Sbjct: 16 SVCYITFHRPEANNTINDTLIEECLQVLNQCETSTVTVVVLEGLPEVFCFGADFQEIYQE 75 Query: 76 MQKGNVKEPKAGYISIDIITDL---LEAARKPSVAAIDGLALGGGLELAMACHARISAPA 132 M++G + S + + DL L+ +++ + G GGL A I+ Sbjct: 76 MKRGRKQAS-----SQEPLYDLWMKLQTGPYVTISHVRGKVNAGGLGFVSATDIAIADQT 130 Query: 133 AQLGLPELQLGVIPGFGGTQRLP---RLVGLTKALEMILTSKPVKAEEGHSLGLIDA 186 A L EL G+ P LP R +G KA M L +KP+ +E GLIDA Sbjct: 131 ASFSLSELLFGLYPAC----VLPFLIRRIGRQKAHYMTLMTKPISVQEASEWGLIDA 183 >4J2U-A nrPDB Length = 365 Score = 47.0 bits (110), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 42/147 (28%), Positives = 71/147 (48%), Gaps = 13/147 (8%) Query: 21 ITLINPP-VNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGR-FSGGFDISGFGEMQK 78 ITL P +N+L+ ++ + + + +V+ +VI R F G DI+ E+ Sbjct: 37 ITLSRPAALNALTCAMVQEIDAALRGWIGDPEVELVVIDAEGPRAFCAGGDIA---ELHG 93 Query: 79 GNVKEPKA---GYISIDI-ITDLLEAARKPSVAAIDGLALGGGLELAMACHAR--ISAPA 132 V A + ++ + D + A KP V+ + G +GGG+ + CHAR I Sbjct: 94 RGVAGDHAFGQDFWRVEYRMNDRIAAFPKPIVSLMQGFTMGGGV--GLGCHARHRIVGET 151 Query: 133 AQLGLPELQLGVIPGFGGTQRLPRLVG 159 +Q+ +PE +G++P GGT L R G Sbjct: 152 SQISMPECAIGLVPDVGGTHLLARAPG 178 >4ZDC-A nrPDB Length = 300 Score = 39.7 bits (91), Expect = 0.004, Method: Compositional matrix adjust. Identities = 44/167 (26%), Positives = 68/167 (40%), Gaps = 10/167 (5%) Query: 20 VITLINPP-VNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGFGEMQK 78 +I LINP +N+L + L E A DV +I + FS G D G + Q Sbjct: 41 IIHLINPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSSGADFKGIAKAQG 100 Query: 79 GNV-KEPK------AGYISIDI-ITDLLEAARKPSVAAIDGLALGGGLELAMACHARIS- 129 + K P + +++ ++ +TD K + ++G A+G L C S Sbjct: 101 DDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSAALVALCDIVYSI 160 Query: 130 APAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAE 176 L P LG+I G T LP G E ++ +KP K + Sbjct: 161 NDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYD 207 >3JU1-A nrPDB Length = 407 Score = 38.5 bits (88), Expect = 0.009, Method: Compositional matrix adjust. Identities = 48/186 (25%), Positives = 85/186 (45%), Gaps = 11/186 (5%) Query: 8 KTVMEVGGDGVAVITL-INPPVNSLSFDVLYNLKSNYEEALSRND--VKAIVITGAKGR- 63 +T+ G V V+TL + +N+L D++ + L + D + +V+ G+ + Sbjct: 42 QTLATASGKLVGVVTLNVEKALNALDLDMVRAMTVQLN--LWKKDPLIACVVLDGSGEKA 99 Query: 64 FSGGFDISGFGEMQ---KGNVKEPKAGYISIDIITD-LLEAARKPSVAAIDGLALGGGLE 119 F G D+ KG V E + + D LL KP + DG+ +GGGL Sbjct: 100 FCAGGDVRALYHASVAAKGQVTEVAKVFFEEEYRLDYLLHTYGKPVLVWGDGIVMGGGLG 159 Query: 120 LAMACHARISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGH 179 L ++ +++ +PE+ +G+ P GG+ L R+ G L + LT+ + A + Sbjct: 160 LMAGASHKVVTETSRIAMPEVTIGLYPDVGGSYFLNRMPG-KMGLFLGLTAYHMNAADAC 218 Query: 180 SLGLID 185 +GL D Sbjct: 219 YVGLAD 224 >2BC1-A nrPDB Length = 490 Score = 32.3 bits (72), Expect = 0.68, Method: Compositional matrix adjust. Identities = 29/99 (29%), Positives = 46/99 (46%), Gaps = 6/99 (6%) Query: 307 LVPRKIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKG 366 L + IK+VA++G G +G +A A V+L +V + L R +L ++ + Sbjct: 189 LENKDIKRVAVVGAGYIGVELAEAFQRKGKEVVLIDVVDTCLAGYYDRDLTDLMAKNMEE 248 Query: 367 SMSQEKFEKTMSLLKGSLDYESF------RDVDMVIEAV 399 Q F +T+ + G+ E DVDMVI AV Sbjct: 249 HGIQLAFGETVKEVAGNGKVEKIITDKNEYDVDMVILAV 287 >5X68-A nrPDB Length = 391 Score = 32.3 bits (72), Expect = 0.71, Method: Compositional matrix adjust. Identities = 19/45 (42%), Positives = 26/45 (57%), Gaps = 2/45 (4%) Query: 301 GVTDRGLVPRKIKKVAIIGGGLMGSGIATALILSNYPVILKEVNE 345 G D ++ RK KVA+IGGGL+GS A L N+ + + E E Sbjct: 5 GSMDSSVIQRK--KVAVIGGGLVGSLQACFLAKRNFQIDVYEARE 47 >5XVM-A nrPDB Length = 478 Score = 32.3 bits (72), Expect = 0.82, Method: Compositional matrix adjust. Identities = 22/98 (22%), Positives = 40/98 (40%), Gaps = 23/98 (23%) Query: 584 GFYLYDDKRKAKPDPELKKYIEKARSISGVKLDPKLANLSEKDIIEMTFFPVVNEACRVF 643 G++ DDK KP EL+++I +ARS K ++ + F +V + Sbjct: 241 GYWFLDDKSTFKPPAELQEFISEARS-------------KGKKLVYIGFGSIVVSNAKEM 287 Query: 644 AEGIAVKAADLDIAGIMGMGFPPYRGGIMFWADSIGSK 681 E + + D+ I+ G W++ +G K Sbjct: 288 TEALVEAVMEADVYCILNKG----------WSERLGDK 315 >5KVH-A nrPDB Length = 543 Score = 30.0 bits (66), Expect = 3.3, Method: Compositional matrix adjust. Identities = 12/24 (50%), Positives = 18/24 (75%) Query: 308 VPRKIKKVAIIGGGLMGSGIATAL 331 + R++K + IIGGG +GS +A AL Sbjct: 220 ISREVKSITIIGGGFLGSELACAL 243 >3E6I-A nrPDB Length = 476 Score = 29.6 bits (65), Expect = 4.5, Method: Compositional matrix adjust. Identities = 25/104 (24%), Positives = 50/104 (48%), Gaps = 13/104 (12%) Query: 331 LILSNYPVILKEVNEKFLEA-GIGRVKANLQSRVRKGSMSQ--EKFEKTMSLLKGSLDYE 387 LIL YP I ++++E+ G R+ A ++ R M + ++ ++L+ +L +E Sbjct: 292 LILMKYPEIEEKLHEEIDRVIGPSRIPA-IKDRQEMPYMDAVVHEIQRFITLVPSNLPHE 350 Query: 388 SFRDV---------DMVIEAVIENISLKQQIFADLEKYCPQHCI 422 + RD V+ ++++ Q F D EK+ P+H + Sbjct: 351 ATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPEHFL 394 >2GVN-A nrPDB Length = 327 Score = 28.9 bits (63), Expect = 7.9, Method: Compositional matrix adjust. Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 5/51 (9%) Query: 8 KTVMEVGGDGVAVITLINPPVNSLSFDVLYNLKSNYEEALSRNDVKAIVIT 58 KT+ + G+ VA I N ++ DVL L E L+R+DV +VIT Sbjct: 47 KTLANIKGEQVASIGSEN-----MTSDVLLTLSKRVNELLARSDVDGVVIT 92 >5CWV-A nrPDB Length = 364 Score = 28.9 bits (63), Expect = 8.0, Method: Compositional matrix adjust. Identities = 13/27 (48%), Positives = 21/27 (77%) Query: 305 RGLVPRKIKKVAIIGGGLMGSGIATAL 331 RGLV +KK A IGGG++G+ +A+++ Sbjct: 277 RGLVVHVLKKNAGIGGGVVGNSLASSI 303 >5FA5-A nrPDB Length = 650 Score = 28.9 bits (63), Expect = 9.2, Method: Compositional matrix adjust. Identities = 11/31 (35%), Positives = 19/31 (61%) Query: 191 AELVTTARRWALDIVGRRKPWVSSVSKTDKL 221 ++L+ + R W IVG+ PW+ SK +K+ Sbjct: 82 SDLLLSGRDWNTLIVGKLSPWIRPDSKVEKI 112 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2WTB-A nrPDB 904 0.0 3ZWA-A nrPDB 755 0.0 6IUM-B nrPDB 720 0.0 5ZRV-A nrPDB 702 0.0 2D3T-A nrPDB 653 0.0 4B3J-A nrPDB 590 e-169 1ZCJ-A nrPDB 532 e-151 3K6J-A nrPDB 417 e-116 3MOG-A nrPDB 390 e-108 6ACQ-A nrPDB 356 2e-98 4KUG-A nrPDB 349 3e-96 1F14-A nrPDB 336 2e-92 4J0E-A nrPDB 335 5e-92 3HDH-A nrPDB 332 3e-91 4PZE-A nrPDB 331 7e-91 6HRD-A nrPDB 310 1e-84 1ZEJ-A nrPDB 278 6e-75 4OM8-A nrPDB 269 3e-72 4DYD-A nrPDB 268 6e-72 3F3S-A nrPDB 255 6e-68 3ADO-A nrPDB 231 1e-60 2IEX-A nrPDB 229 2e-60 3T88-A nrPDB 227 2e-59 5ZAI-A nrPDB 225 4e-59 4EML-A nrPDB 220 2e-57 2UZF-A nrPDB 219 4e-57 2DUB-A nrPDB 218 1e-56 5Z7R-A nrPDB 215 7e-56 2HW5-A nrPDB 211 1e-54 3MOY-A nrPDB 209 3e-54 6OJM-A nrPDB 209 3e-54 3H81-A nrPDB 209 4e-54 2VSU-C nrPDB 205 5e-53 3OME-A nrPDB 203 3e-52 2PPY-A nrPDB 200 2e-51 4FZW-A nrPDB 194 1e-49 5YLO-A nrPDB 191 1e-48 1NZY-B nrPDB 189 5e-48 1EF9-A nrPDB 189 5e-48 4JWV-A nrPDB 188 7e-48 4JCS-A nrPDB 187 1e-47 5WYB-B nrPDB 184 2e-46 3T8B-A nrPDB 183 2e-46 5VE2-A nrPDB 179 3e-45 4ZU2-A nrPDB 179 4e-45 5JBW-A nrPDB 176 2e-44 1XX4-A nrPDB 171 8e-43 4FZW-C nrPDB 171 1e-42 3I47-A nrPDB 169 3e-42 2A81-A nrPDB 169 3e-42 4JFC-A nrPDB 169 6e-42 4IZC-A nrPDB 168 8e-42 3HIN-A nrPDB 166 3e-41 3HE2-A nrPDB 166 3e-41 3BPT-A nrPDB 161 1e-39 5KJP-A nrPDB 160 2e-39 4Q1J-A nrPDB 159 5e-39 4HC8-A nrPDB 154 1e-37 4JSB-A nrPDB 154 2e-37 5MRE-88 nrPDB 152 5e-37 4HDT-A nrPDB 148 9e-36 4J2U-A nrPDB 147 2e-35 3LAO-A nrPDB 146 3e-35 3HP0-A nrPDB 142 5e-34 2NP9-A nrPDB 125 5e-29 3M6N-A nrPDB 122 5e-28 Sequences not found previously or not previously below threshold: 3JU1-A nrPDB 107 2e-23 4ZDC-A nrPDB 77 3e-14 2BC1-A nrPDB 48 2e-05 6AON-A nrPDB 45 2e-04 2GF2-A nrPDB 44 2e-04 5ER0-A nrPDB 43 4e-04 5U8W-A nrPDB 42 0.001 3CTV-A nrPDB 41 0.002 4WJI-A nrPDB 41 0.002 4R16-A nrPDB 40 0.003 1NHQ-A nrPDB 40 0.003 4D3F-A nrPDB 40 0.003 3OJO-A nrPDB 40 0.003 4OQZ-A nrPDB 39 0.006 3BF0-A nrPDB 39 0.007 4XRR-A nrPDB 39 0.009 3KVE-A nrPDB 38 0.012 4ND4-A nrPDB 38 0.012 1F8S-A nrPDB 38 0.015 1PS9-A nrPDB 38 0.019 1LTH-T nrPDB 37 0.023 5X6R-A nrPDB 37 0.024 2UYY-A nrPDB 37 0.026 4PLF-A nrPDB 37 0.027 3GGO-A nrPDB 37 0.028 2G5C-A nrPDB 37 0.028 1REO-A nrPDB 37 0.028 1MV8-A nrPDB 37 0.031 4J90-A nrPDB 37 0.035 2HMT-A nrPDB 37 0.036 5BUT-A nrPDB 37 0.040 1A5Z-A nrPDB 37 0.040 3G0O-A nrPDB 37 0.043 4HTF-A nrPDB 36 0.045 2EQ6-A nrPDB 36 0.045 1VPD-A nrPDB 36 0.047 2VHY-A nrPDB 36 0.053 5Y77-A nrPDB 36 0.053 4OQY-A nrPDB 36 0.057 5JE8-A nrPDB 36 0.059 6C6P-A nrPDB 36 0.068 3PQF-A nrPDB 36 0.069 5DT9-A nrPDB 35 0.087 3VTF-A nrPDB 35 0.092 3DOJ-A nrPDB 35 0.11 3TL2-A nrPDB 35 0.11 3TH6-A nrPDB 35 0.12 6IHE-A nrPDB 35 0.13 1SEZ-A nrPDB 35 0.13 6ABJ-A nrPDB 35 0.14 3ZHB-A nrPDB 35 0.15 6QGL-A nrPDB 35 0.16 2XD4-A nrPDB 34 0.19 5TR3-A nrPDB 34 0.19 3LAD-A nrPDB 34 0.19 2YQ5-A nrPDB 34 0.20 4PRK-A nrPDB 34 0.21 4K28-A nrPDB 34 0.22 3VH2-A nrPDB 34 0.23 3T7E-A nrPDB 34 0.23 3X2F-A nrPDB 34 0.23 4ZGS-A nrPDB 34 0.24 5N2I-A nrPDB 34 0.26 3WSV-A nrPDB 34 0.26 4E21-A nrPDB 34 0.27 4A7P-A nrPDB 34 0.28 6BZ0-A nrPDB 34 0.30 5O3Z-A nrPDB 34 0.30 4MOP-A nrPDB 34 0.32 3G5Q-A nrPDB 34 0.32 2V3B-A nrPDB 34 0.32 3KB6-A nrPDB 34 0.33 5X68-A nrPDB 34 0.34 4UEJ-A nrPDB 34 0.36 5JFC-L nrPDB 34 0.37 3ZZN-A nrPDB 34 0.37 5VJ7-A nrPDB 33 0.38 5MH6-A nrPDB 33 0.40 4FFM-A nrPDB 33 0.43 1GPJ-A nrPDB 33 0.46 3NJ4-A nrPDB 33 0.46 1Q1R-A nrPDB 33 0.47 3HWR-A nrPDB 33 0.48 1XDW-A nrPDB 33 0.48 5UYY-A nrPDB 33 0.54 1OC4-A nrPDB 33 0.54 2EW2-A nrPDB 33 0.56 4ZCC-A nrPDB 33 0.57 3GSZ-A nrPDB 33 0.57 4OX3-A nrPDB 33 0.60 3ATQ-A nrPDB 33 0.60 3PEF-A nrPDB 32 0.74 3FG2-P nrPDB 32 0.74 3AXS-A nrPDB 32 0.74 2AVN-A nrPDB 32 0.80 5JXW-A nrPDB 32 0.84 3KKJ-A nrPDB 32 0.84 1AHH-A nrPDB 32 0.84 3KYB-A nrPDB 32 0.88 5ZIK-A nrPDB 32 0.90 6CI9-A nrPDB 32 0.91 4DLA-A nrPDB 32 0.93 1Y6J-A nrPDB 32 0.96 3EEQ-A nrPDB 32 0.99 4JJI-A nrPDB 32 1.00 4CPD-A nrPDB 32 1.0 1YB4-A nrPDB 32 1.0 4A6N-B nrPDB 32 1.0 1LSS-A nrPDB 32 1.1 3WFI-A nrPDB 32 1.1 3BHF-A nrPDB 32 1.1 3ENK-A nrPDB 32 1.1 3U9S-B nrPDB 32 1.2 3Q3C-A nrPDB 32 1.3 2V8U-A nrPDB 32 1.3 5T5Q-A nrPDB 32 1.3 5OCM-A nrPDB 32 1.3 3PDU-A nrPDB 32 1.3 3LXD-A nrPDB 32 1.4 3DC2-A nrPDB 32 1.4 2CZG-A nrPDB 32 1.4 3N58-A nrPDB 31 1.5 3I83-A nrPDB 31 1.5 4JCQ-A nrPDB 31 1.5 1ON3-A nrPDB 31 1.7 5KVH-A nrPDB 31 1.7 1C0L-A nrPDB 31 1.7 4KWB-A nrPDB 31 1.7 2EEZ-A nrPDB 31 1.8 4RQU-A nrPDB 31 1.9 3NEP-X nrPDB 31 1.9 3H2Z-A nrPDB 31 2.0 2RIR-A nrPDB 31 2.1 3AEO-A nrPDB 31 2.1 3RST-A nrPDB 31 2.1 2W8Z-A nrPDB 31 2.2 2LDB-A nrPDB 31 2.2 3K30-A nrPDB 31 2.2 4RPJ-A nrPDB 31 2.3 1X54-A nrPDB 31 2.4 4DGK-A nrPDB 30 2.6 2PA3-A nrPDB 30 2.6 2EER-A nrPDB 30 2.7 1ZOV-A nrPDB 30 2.8 1PZF-A nrPDB 30 3.2 6APH-A nrPDB 30 3.3 5A9T-A nrPDB 30 3.4 2DFV-A nrPDB 30 3.5 1GQY-A nrPDB 30 3.5 3ABT-A nrPDB 30 3.6 1CF2-P nrPDB 30 3.6 2P4Q-A nrPDB 30 3.7 3B40-A nrPDB 30 3.8 1BG6-A nrPDB 30 3.8 4WEQ-A nrPDB 30 4.2 1Z82-A nrPDB 30 4.2 4XGI-A nrPDB 30 4.3 5J7X-A nrPDB 30 4.4 3GVH-A nrPDB 30 4.4 1QO8-A nrPDB 30 4.4 3PII-A nrPDB 30 4.5 3CKY-A nrPDB 30 4.6 4O6R-A nrPDB 30 4.7 4FX9-A nrPDB 30 4.9 5L3D-A nrPDB 30 5.1 4X2R-A nrPDB 30 5.2 3WTC-A nrPDB 30 5.3 3ICS-A nrPDB 30 5.3 2HQM-A nrPDB 30 5.4 3N6R-B nrPDB 29 5.8 3VPX-A nrPDB 29 6.1 2E3D-A nrPDB 29 6.3 3IHG-A nrPDB 29 6.9 4D3S-A nrPDB 29 7.0 4YWE-A nrPDB 29 7.3 2ZYA-A nrPDB 29 7.5 3ETH-A nrPDB 29 8.9 5VVW-A nrPDB 29 9.4 4ROS-A nrPDB 29 9.8 >2WTB-A nrPDB Length = 725 Score = 904 bits (2337), Expect = 0.0, Method: Composition-based stats. Identities = 725/725 (100%), Positives = 725/725 (100%) Query: 1 MDSRTKGKTVMEVGGDGVAVITLINPPVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGA 60 MDSRTKGKTVMEVGGDGVAVITLINPPVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGA Sbjct: 1 MDSRTKGKTVMEVGGDGVAVITLINPPVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGA 60 Query: 61 KGRFSGGFDISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLEL 120 KGRFSGGFDISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLEL Sbjct: 61 KGRFSGGFDISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLEL 120 Query: 121 AMACHARISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHS 180 AMACHARISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHS Sbjct: 121 AMACHARISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHS 180 Query: 181 LGLIDAVVPPAELVTTARRWALDIVGRRKPWVSSVSKTDKLPPLGEAREILTFAKAQTLK 240 LGLIDAVVPPAELVTTARRWALDIVGRRKPWVSSVSKTDKLPPLGEAREILTFAKAQTLK Sbjct: 181 LGLIDAVVPPAELVTTARRWALDIVGRRKPWVSSVSKTDKLPPLGEAREILTFAKAQTLK 240 Query: 241 RAPNMKHPLMCLDAIEVGIVSGPRAGLEKEAEVASQVVKLDTTKGLIHVFFSQRGTAKVP 300 RAPNMKHPLMCLDAIEVGIVSGPRAGLEKEAEVASQVVKLDTTKGLIHVFFSQRGTAKVP Sbjct: 241 RAPNMKHPLMCLDAIEVGIVSGPRAGLEKEAEVASQVVKLDTTKGLIHVFFSQRGTAKVP 300 Query: 301 GVTDRGLVPRKIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQ 360 GVTDRGLVPRKIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQ Sbjct: 301 GVTDRGLVPRKIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQ 360 Query: 361 SRVRKGSMSQEKFEKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADLEKYCPQH 420 SRVRKGSMSQEKFEKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADLEKYCPQH Sbjct: 361 SRVRKGSMSQEKFEKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADLEKYCPQH 420 Query: 421 CILASNTSTIDLNKIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDVG 480 CILASNTSTIDLNKIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDVG Sbjct: 421 CILASNTSTIDLNKIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDVG 480 Query: 481 KKIKKTPVVVGNCTGFAVNRMFFPYTQAAMFLVECGADPYLIDRAISKFGMPMGPFRLCD 540 KKIKKTPVVVGNCTGFAVNRMFFPYTQAAMFLVECGADPYLIDRAISKFGMPMGPFRLCD Sbjct: 481 KKIKKTPVVVGNCTGFAVNRMFFPYTQAAMFLVECGADPYLIDRAISKFGMPMGPFRLCD 540 Query: 541 LVGFGVAIATATQFIENFSERTYKSMIIPLMQEDKRAGEATRKGFYLYDDKRKAKPDPEL 600 LVGFGVAIATATQFIENFSERTYKSMIIPLMQEDKRAGEATRKGFYLYDDKRKAKPDPEL Sbjct: 541 LVGFGVAIATATQFIENFSERTYKSMIIPLMQEDKRAGEATRKGFYLYDDKRKAKPDPEL 600 Query: 601 KKYIEKARSISGVKLDPKLANLSEKDIIEMTFFPVVNEACRVFAEGIAVKAADLDIAGIM 660 KKYIEKARSISGVKLDPKLANLSEKDIIEMTFFPVVNEACRVFAEGIAVKAADLDIAGIM Sbjct: 601 KKYIEKARSISGVKLDPKLANLSEKDIIEMTFFPVVNEACRVFAEGIAVKAADLDIAGIM 660 Query: 661 GMGFPPYRGGIMFWADSIGSKYIYSRLDEWSKAYGEFFKPCAFLAERGSKGVLLSAPVKQ 720 GMGFPPYRGGIMFWADSIGSKYIYSRLDEWSKAYGEFFKPCAFLAERGSKGVLLSAPVKQ Sbjct: 661 GMGFPPYRGGIMFWADSIGSKYIYSRLDEWSKAYGEFFKPCAFLAERGSKGVLLSAPVKQ 720 Query: 721 ASSRL 725 ASSRL Sbjct: 721 ASSRL 725 >3ZWA-A nrPDB Length = 742 Score = 755 bits (1948), Expect = 0.0, Method: Composition-based stats. Identities = 232/727 (31%), Positives = 384/727 (52%), Gaps = 43/727 (5%) Query: 17 GVAVITLINPPVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGFGEM 76 +A+I L NPPVN++S V+ +++ ++A S + VKAIVI GA G F G DI GF Sbjct: 30 SLAMIRLCNPPVNAVSPTVIREVRNGLQKAGSDHTVKAIVICGANGNFCAGADIHGFSAF 89 Query: 77 QKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAAQLG 136 G +++ + D ++ +KP +AAI G+ALGGGLELA+ CH RI+ A++G Sbjct: 90 TPG---------LALGSLVDEIQRYQKPVLAAIQGVALGGGLELALGCHYRIANAKARVG 140 Query: 137 LPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAELVTT 196 LPE+ LG++PG GTQ LPR+VG+ AL++I + K + A+E LG++DAVV ++ V Sbjct: 141 LPEVTLGILPGARGTQLLPRVVGVPVALDLITSGKYLSADEALRLGILDAVV-KSDPVEE 199 Query: 197 ARRWALDIVGRRKPWVSSVSKTDKLPPLGEAREILTFAKAQTLKRAPNMKHPLMCLDAIE 256 A ++A I+ KP +P L + A A+ K+ P + P C+ +I+ Sbjct: 200 AIKFAQKIID--KPIEPRRIFNKPVPSLPNMDSVFAEAIAKVRKQYPGVLAPETCVRSIQ 257 Query: 257 VGIVSGPRAGLEKEAEVASQVVKLDTTKGLIHVFFSQRGTAKVP---GVTDRGLVPRKIK 313 + G+++E ++ + K L + FF+++ K G + + + + Sbjct: 258 ASVKHPYEVGIKEEEKLFMYLRASGQAKALQYAFFAEKSANKWSTPSGASWKTASAQPVS 317 Query: 314 KVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEKF 373 V ++G G MG GIA + V+ E + K L+A + L+ + + + Sbjct: 318 SVGVLGLGTMGRGIAISFARVGISVVAVESDPKQLDAAKKIITFTLEKEASRAHQNGQAS 377 Query: 374 EKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADLEKYCPQHCILASNTSTIDLN 433 K L+ S + VD+V+EAV E+++LK+++FA+L C L +NTS ++++ Sbjct: 378 AKP--KLRFSSSTKELSTVDLVVEAVFEDMNLKKKVFAELSALCKPGAFLCTNTSALNVD 435 Query: 434 KIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDVGKKIKKTPVVVGNC 493 I T ++G HFFSPAH+M LLE++ + ++S I ++ + KKI K VVVGNC Sbjct: 436 DIASSTDRPQLVIGTHFFSPAHVMRLLEVIPSRYSSPTTIATVMSLSKKIGKIGVVVGNC 495 Query: 494 TGFAVNRMFFPYTQAAMFLVECGADPYLIDRAISKFGMPMGPFRLCDLVGFGVAIATA-- 551 GF NRM PY FL+E G+ P +D + +FG MGPFR+ DL G V Sbjct: 496 YGFVGNRMLAPYYNQGFFLLEEGSKPEDVDGVLEEFGFKMGPFRVSDLAGLDVGWKIRKG 555 Query: 552 -----------TQFIENFSERTYKSMIIPLMQEDKRAGEATRKGFYLYDDK--RKAKPDP 598 T + + R S + ++ E R G+ T KG+Y YD R KPDP Sbjct: 556 QGLTGPSLPPGTPVRKRGNSRY--SPLGDMLCEAGRFGQKTGKGWYQYDKPLGRIHKPDP 613 Query: 599 ELKKYIEKARSISGVKLDPKLANLSEKDIIEMTFFPVVNEACRVFAEGIAVKAADLDIAG 658 L ++ + R + ++ +S+++I+E + ++NEA R+ EG+A + +D+ Sbjct: 614 WLSTFLSQYREVHHIEQ----RTISKEEILERCLYSLINEAFRILEEGMAARPEHIDVIY 669 Query: 659 IMGMGFPPYRGGIMFWADSIGSKYIYSRLDEWSKAYGE--FFKPCAFLAERGSKGVLLSA 716 + G G+P ++GG MF+A S+G + +L ++ + + +P +L ++G S Sbjct: 670 LHGYGWPRHKGGPMFYAASVGLPTVLEKLQKYYRQNPDIPQLEPSDYLRRLVAQG---SP 726 Query: 717 PVKQASS 723 P+K+ S Sbjct: 727 PLKEWQS 733 >6IUM-B nrPDB Length = 701 Score = 720 bits (1858), Expect = 0.0, Method: Composition-based stats. Identities = 269/706 (38%), Positives = 394/706 (55%), Gaps = 22/706 (3%) Query: 9 TVMEVGGDGVAVITLINPPVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGF 68 T DGVAVITL NPPVN L + AL VKAIVITGA FSGG Sbjct: 2 TAQYQVQDGVAVITLDNPPVNGLGHSTRLGIVEGMTRALDDAAVKAIVITGAGKAFSGGA 61 Query: 69 DISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARI 128 DI F + ++ + +LE + KP VAA+ +A+GGGLELA+ C+ R+ Sbjct: 62 DIREFNTPKAMQE-------PTLHSVIRVLEGSSKPVVAAVHSVAMGGGLELALGCNYRV 114 Query: 129 SAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVV 188 ++ AQ+ LPE++LG++PG GGTQRLPR++GL A MI++ PV +E+ L D +V Sbjct: 115 ASKGAQIALPEVKLGLLPGAGGTQRLPRVIGLEAAANMIVSGTPVLSEKFAGTKLFDEIV 174 Query: 189 PPAELVTTARRWALDIVGRRKPWVSSVSKTDKLPPLGEARE-ILTFAKAQTLKRAPNMKH 247 +++ A ++A ++ P K L E E L FA+ A N Sbjct: 175 -DGDVLPAAVKFAQNVGAATGPH----PKVRDLKVRHENPEGYLGFARNTVAAMAKNFPA 229 Query: 248 PLMCLDAIEVGIVSGPRAGLEKEAEVASQVVKLDTTKGLIHVFFSQRGTAKVPGVTDRGL 307 PL CL+A+ G + GL++E E +V ++ L H FF +R +K+P V G Sbjct: 230 PLKCLEAV-AGSLKPFEQGLKQEREGFLYLVTTPESRALRHAFFGERAASKIPDV-PEGT 287 Query: 308 VPRKIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGS 367 RKI+KVA+IG G MG GI+ + + PV + E ++ L+ G+G ++ N ++ +KG Sbjct: 288 PTRKIEKVAVIGAGTMGGGISMNFLNAGIPVTILETKQEALDRGVGIIRKNYENSAKKGK 347 Query: 368 MSQEKFEKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADLEKYCPQHCILASNT 427 ++QEK E+ M LL +L Y+ +D D++IEAV E + +K+ +F L++ Q ILASNT Sbjct: 348 LTQEKVEQRMGLLSTTLSYDDLKDADLIIEAVFEEMGVKETVFKKLDEVAKQGAILASNT 407 Query: 428 STIDLNKIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDVGKKIKKTP 487 ST+D+NKI TK +VG HFFSPA++M LLE+VR T V+ ++ VGKKIKKT Sbjct: 408 STLDVNKIASFTKRPQDVVGMHFFSPANVMKLLEVVRGEKTGKDVLATVMQVGKKIKKTA 467 Query: 488 VVVGNCTGFAVNRMFFPYTQAAMFLVECGADPYLIDRAISKFGMPMGPFRLCDLVGFGVA 547 VV G C GF NRM Y++ A +L++ GA P +D+AI KFG MGPFR+ DL G + Sbjct: 468 VVSGVCDGFIGNRMIEQYSRQAGYLLDEGALPEQVDKAIEKFGFAMGPFRMGDLAGNDIG 527 Query: 548 IATATQFIENFSERTYKSMIIPLMQEDKRAGEATRKGFYLYD-DKRKAKPDPELKKYIEK 606 A + + E Y S L+ E R G+ T G+Y Y RK P+ ++ I + Sbjct: 528 WAIRKRRAVDKPEIQY-SKTADLLCEMGRFGQKTGAGWYDYKAGDRKPYPNQQVNDMIVQ 586 Query: 607 ARSISGVKLDPKLANLSEKDIIEMTFFPVVNEACRVFAEGIAVKAADLDIAGIMGMGFPP 666 G+ +S+++I+E F +VNE R+ EGIA KA+D+D+ + G GFP Sbjct: 587 HSKDLGI----TRRKISDEEIVERLVFALVNEGARILEEGIASKASDIDMVYLTGYGFPL 642 Query: 667 YRGGIMFWADSIGSKYIYSRLDEWSKAY-GEFFKPCAFLAERGSKG 711 +RGG M +AD +G + + ++K Y GE ++ L + +G Sbjct: 643 FRGGPMLYADQVGLYNVALSMKRYAKGYHGEAWQVAPLLQKLADEG 688 >5ZRV-A nrPDB Length = 763 Score = 702 bits (1811), Expect = 0.0, Method: Composition-based stats. Identities = 229/732 (31%), Positives = 359/732 (49%), Gaps = 44/732 (6%) Query: 8 KTVMEVGGDG-VAVITLINP--PVNSLSFDVLYNLKSNYEEALSRNDVK-AIVITGAKGR 63 +T + G G VAV+ + +P VN+LS ++ E + + ++ A++I+ G Sbjct: 38 RTHINYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGC 97 Query: 64 FSGGFDISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMA 123 F G DI+ + ++E I + LE + KP VAAI+G LGGGLE+A++ Sbjct: 98 FIAGADINMLAACK--TLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAIS 155 Query: 124 CHARISAPAAQ--LGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSL 181 C RI+ + LG PE+ LG +PG GGTQRLP++VG+ AL+M+LT + ++A+ + Sbjct: 156 CQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKM 215 Query: 182 GLIDAVVPP-------------AELVTTARRWALDIVGRRKPWVSSVSKTDKLPPLGEAR 228 GL+D +V P L A +A + ++ +S + L Sbjct: 216 GLVDQLVEPLGPGLKPPEERTIEYLEEVAITFAKGLADKK---ISPKRDKGLVEKLTAYA 272 Query: 229 EILTFAKAQTLKRAPN---------MKHPLMCLDAIEVGIVSGPRAGLEKEAEVASQVVK 279 + F + Q K+ PL +D ++ GI G AG E++ ++V Sbjct: 273 MTIPFVRQQVYKKVEEKVRKQTKGLYPAPLKIIDVVKTGIEQGSDAGYLCESQKFGELVM 332 Query: 280 LDTTKGLIHVFFSQRGTAKVPGVTDRGLVPRKIKKVAIIGGGLMGSGIATALILSNYPVI 339 +K L+ ++ Q K G + +K +AI+G GLMG+GIA + I Sbjct: 333 TKESKALMGLYHGQVLCKK----NKFGAPQKDVKHLAILGAGLMGAGIAQVSVDKGLKTI 388 Query: 340 LKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEKFEKTMSLLKGSLDYESFRDVDMVIEAV 399 LK+ L+ G +V L +V+K +++ + + S L G LDY+ F DMVIEAV Sbjct: 389 LKDATLTALDRGQQQVFKGLNDKVKKKALTSFERDSIFSNLTGQLDYQGFEKADMVIEAV 448 Query: 400 IENISLKQQIFADLEKYCPQHCILASNTSTIDLNKIGERTKSQDRIVGAHFFSPAHIMPL 459 E++SLK ++ ++E P HCI ASNTS + +++I +K ++++G H+FSP M L Sbjct: 449 FEDLSLKHRVLKEVEAVIPDHCIFASNTSALPISEIAAVSKRPEKVIGMHYFSPVDKMQL 508 Query: 460 LEIVRTNHTSAQVIVDLLDVGKKIKKTPVVVGNCTGFAVNRMFFPYTQAAMFLVECGADP 519 LEI+ T TS + VG K K +VV + GF R P + +++ G DP Sbjct: 509 LEIITTEKTSKDTSASAVAVGLKQGKVIIVVKDGPGFYTTRCLAPMMSEVIRILQEGVDP 568 Query: 520 YLIDRAISKFGMPMGPFRLCDLVGFGVAIATATQFIENFSER--TYKSMIIPLMQEDKRA 577 +D + FG P+G L D VG VA A + F ER ++ M Sbjct: 569 KKLDSLTTSFGFPVGAATLVDEVGVDVAKHVAEDLGKVFGERFGGGNPELLTQMVSKGFL 628 Query: 578 GEATRKGFYLYDDKRKAKPDPELKKYIEKARSISGVKLDPKLANLSEKDIIEMTFFPVVN 637 G + KGFY+Y + K K +L ++ ++ +KL PK S++DI VN Sbjct: 629 GRKSGKGFYIYQEGVKRK---DLNSDMDSI--LASLKLPPKSEVSSDEDIQFRLVTRFVN 683 Query: 638 EACRVFAEGIAVKAADLDIAGIMGMGFPPYRGGIMFWADSIGSKYIYSRLDEWSKAYGEF 697 EA EGI A+ DI + G+GFPP GG + D G++ I RL ++ AYG+ Sbjct: 684 EAVMCLQEGILATPAEGDIGAVFGLGFPPCLGGPFRFVDLYGAQKIVDRLKKYEAAYGKQ 743 Query: 698 FKPCAFLAERGS 709 F PC LA+ + Sbjct: 744 FTPCQLLADHAN 755 >2D3T-A nrPDB Length = 715 Score = 653 bits (1685), Expect = 0.0, Method: Composition-based stats. Identities = 228/690 (33%), Positives = 359/690 (52%), Gaps = 14/690 (2%) Query: 28 VNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGFGEMQKGNVKEPKAG 87 VN + L L+ + + VK ++++ K F G DI+ F E K E AG Sbjct: 29 VNKFNRLTLNELRQAVDAIKADASVKGVIVSSGKDVFIVGADITEFVENFKLPDAELIAG 88 Query: 88 YISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAAQLGLPELQLGVIPG 147 + + I E P+VAAI+G+ALGGGLE+ +A R+ A +A++GLPE++LG+ PG Sbjct: 89 NLEANKIFSDFEDLNVPTVAAINGIALGGGLEMCLAADFRVMADSAKIGLPEVKLGIYPG 148 Query: 148 FGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAELVTTARRWALD-IVG 206 FGGT RLPRL+G+ A+E I + K +AE+ + +DAVV +L A I G Sbjct: 149 FGGTVRLPRLIGVDNAVEWIASGKENRAEDALKVSAVDAVVTADKLGAAALDLIKRAISG 208 Query: 207 RRKPWVSSVSKTDKLPPLGEAREILTFAKAQTL---KRAPNMKHPLMCLDAIEVGIVSGP 263 K +KL L +++ F A+ + PN P+ + I+ G Sbjct: 209 ELDYKAKRQPKLEKLK-LNAIEQMMAFETAKGFVAGQAGPNYPAPVEAIKTIQKAANFGR 267 Query: 264 RAGLEKEAEVASQVVKLDTTKGLIHVFFSQRGTAKVPGVTDRGLVPRKIKKVAIIGGGLM 323 LE EA +++ K + LI +F + + K V D+ + + +K+ A++G G+M Sbjct: 268 DKALEVEAAGFAKLAKTSASNCLIGLFLNDQELKKKAKVYDK--IAKDVKQAAVLGAGIM 325 Query: 324 GSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEKFEKTMSLLKGS 383 G GIA P+++K++NE +E G+ L RV KG M+ K + ++ ++ + Sbjct: 326 GGGIAYQSASKGTPILMKDINEHGIEQGLAEAAKLLVGRVDKGRMTPAKMAEVLNGIRPT 385 Query: 384 LDYESFRDVDMVIEAVIENISLKQQIFADLEKYCPQHCILASNTSTIDLNKIGERTKSQD 443 L Y F +VD+V+EAV+EN +KQ + A++E + + ILASNTSTI ++ + + K + Sbjct: 386 LSYGDFGNVDLVVEAVVENPKVKQAVLAEVENHVREDAILASNTSTISISLLAKALKRPE 445 Query: 444 RIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDVGKKIKKTPVVVGNCTGFAVNRMFF 503 VG HFF+P H+MPL+E++R +S + + KK+ K P+VV +C GF VNR+ F Sbjct: 446 NFVGMHFFNPVHMMPLVEVIRGEKSSDLAVATTVAYAKKMGKNPIVVNDCPGFLVNRVLF 505 Query: 504 PYTQAAMFLVECGADPYLIDRAISKFGMPMGPFRLCDLVGFGVAIATATQFIENFSERTY 563 PY LV G D ID+ + KFG PMGP L D+VG E F +R Sbjct: 506 PYFGGFAKLVSAGVDFVRIDKVMEKFGWPMGPAYLMDVVGIDTGHHGRDVMAEGFPDRMK 565 Query: 564 --KSMIIPLMQEDKRAGEATRKGFYLYDDKRKAKPDPELKKYIEKARSISGVKLDPKLAN 621 + I + E KR G+ KGFY Y+ +K K KK ++ + + + + Sbjct: 566 DDRRSAIDALYEAKRLGQKNGKGFYAYEADKKGKQ----KKLVDSSVLEVLKPIVYEQRD 621 Query: 622 LSEKDIIEMTFFPVVNEACRVFAEGIAVKAADLDIAGIMGMGFPPYRGGIMFWADSIGSK 681 ++++DII P+ E R +GI AA+ D+ + G+GFP +RGG + + DSIG Sbjct: 622 VTDEDIINWMMIPLCLETVRCLEDGIVETAAEADMGLVYGIGFPLFRGGALRYIDSIGVA 681 Query: 682 YIYSRLDEWSKAYGEFFKPCAFLAERGSKG 711 + D++++ G + P A L E G Sbjct: 682 EFVALADQYAE-LGALYHPTAKLREMAKNG 710 >4B3J-A nrPDB Length = 736 Score = 590 bits (1520), Expect = e-169, Method: Composition-based stats. Identities = 208/719 (28%), Positives = 335/719 (46%), Gaps = 41/719 (5%) Query: 15 GDGVAVITLINPP--VNSLSFDVLYNLKSNYEE-ALSRNDVKAIVITGAKGRFSGGFDIS 71 DG+ +T+ +P N ++ + ++ + ++ + +V+ AK F G D+ Sbjct: 28 ADGIVTLTMDDPSGSTNVMNEAYIESMGKAVDRLVAEKDSITGVVVASAKKTFFAGGDVK 87 Query: 72 GFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAP 131 + + + + +I LE KP VAAI+G ALGGGLE+A+ACH RI+A Sbjct: 88 TMIQARPEDAGDVFNTVETIKRQLRTLETLGKPVVAAINGAALGGGLEIALACHHRIAAD 147 Query: 132 --AAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILT-SKPVKAEEGHSLGLIDAVV 188 +QLGLPE+ LG++PG GG R R+ G+ A +L K + +GL+D +V Sbjct: 148 VKGSQLGLPEVTLGLLPGGGGVTRTVRMFGIQNAFVSVLAQGTRFKPAKAKEIGLVDELV 207 Query: 189 PP-AELVTTARRWALDIVGRR------KPWVSSVSK----TDKLPPLGEAREILTFAKAQ 237 ELV A+ W + + +PW K T P L + Sbjct: 208 ATVEELVPAAKAWIKEELKANPDGAGVQPWDKKGYKMPGGTPSSPGLAAILPSFPSNLRK 267 Query: 238 TLKRAPNMKHPLMCLDAIEVGIVSGPRAGLEKEAEVASQVVKLDTTKGLIHVFFSQRGTA 297 LK AP M P L A G E+ + +V K ++ FF Sbjct: 268 QLKGAP-MPAPRAILAAAVEGAQVDFDTASRIESRYFASLVTGQVAKNMMQAFFFDLQAI 326 Query: 298 KVPGVTDRGLVPRKIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKA 357 G G+ IK++ ++G G+MG+GIA + Y V+LK+V+ + G G + Sbjct: 327 NAGGSRPEGIGKTPIKRIGVLGAGMMGAGIAYVSAKAGYEVVLKDVSLEAAAKGKGYSEK 386 Query: 358 NLQSRVRKGSMSQEKFEKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADLEKYC 417 + +G +QE+ + ++ + + D F+ VD VIEAV EN LK ++F ++E Sbjct: 387 LEAKALERGRTTQERSDALLARITPTADAADFKGVDFVIEAVFENQELKHKVFGEIEDIV 446 Query: 418 PQHCILASNTSTIDLNKIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLL 477 + IL SNTST+ + + K Q+ +G HFFSP MPL+EI++ TS + + + Sbjct: 447 EPNAILGSNTSTLPITGLATGVKRQEDFIGIHFFSPVDKMPLVEIIKGEKTSDEALARVF 506 Query: 478 DVGKKIKKTPVVVGNCTGFAVNRMFFPYTQAAMFLVECGADPYLIDRAISKFGMPMGPFR 537 D I KTP+VV + GF +R+ + A+ ++ G +P I++A S+ G P P + Sbjct: 507 DYTLAIGKTPIVVNDSRGFFTSRVIGTFVNEALAMLGEGVEPASIEQAGSQAGYPAPPLQ 566 Query: 538 LCDLVGFGVAI--ATATQFIENFSERTYKSM----IIPLMQEDKRAGEATRKGFYLYDDK 591 L D + + A AT+ + TY+ ++ M E R+G GFY Y D Sbjct: 567 LSDELNLELMHKIAVATRKGVEDAGGTYQPHPAEAVVEKMIELGRSGRLKGAGFYEYADG 626 Query: 592 RKAKPDPELKKYIEKARSISGVKLDPKLANLSEKDIIEMTFFPVVNEACRVFAEGIAVKA 651 +++ P L++ + S P L +D+I+ F E + EG+ Sbjct: 627 KRSGLWPGLRETFKSGSS------QPPL-----QDMIDRMLFAEALETQKCLDEGVLTST 675 Query: 652 ADLDIAGIMGMGFPPYRGG----IMFWADSIGS--KYIYSRLDEWSKAYGEFFKPCAFL 704 AD +I IMG+GFPP+ GG I+ ++ G+ +R E + AYG+ F P L Sbjct: 676 ADANIGSIMGIGFPPWTGGSAQFIVGYSGPAGTGKAAFVARARELAAAYGDRFLPPESL 734 >1ZCJ-A nrPDB Length = 463 Score = 532 bits (1371), Expect = e-151, Method: Composition-based stats. Identities = 138/465 (29%), Positives = 234/465 (50%), Gaps = 31/465 (6%) Query: 279 KLDTTKGLIHVFFSQRGTAKVP---GVTDRGLVPRKIKKVAIIGGGLMGSGIATALILSN 335 K L + FF+++ K G + + + + V ++G G MG GIA + Sbjct: 1 ASGQAKALQYAFFAEKSANKWSTPSGASWKTASAQPVSSVGVLGLGTMGRGIAISFARVG 60 Query: 336 YPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEKFEKTMSLLKGSLDYESFRDVDMV 395 V+ E + K L+A + L+ + + + K L+ S + VD+V Sbjct: 61 ISVVAVESDPKQLDAAKKIITFTLEKEASRAHQNGQASAKP--KLRFSSSTKELSTVDLV 118 Query: 396 IEAVIENISLKQQIFADLEKYCPQHCILASNTSTIDLNKIGERTKSQDRIVGAHFFSPAH 455 +EAV E+++LK+++FA+L C L +NTS ++++ I T ++G HFFSPAH Sbjct: 119 VEAVFEDMNLKKKVFAELSALCKPGAFLCTNTSALNVDDIASSTDRPQLVIGTHFFSPAH 178 Query: 456 IMPLLEIVRTNHTSAQVIVDLLDVGKKIKKTPVVVGNCTGFAVNRMFFPYTQAAMFLVEC 515 +M LLE++ + ++S I ++ + KKI K VVVGNC GF NRM PY FL+E Sbjct: 179 VMRLLEVIPSRYSSPTTIATVMSLSKKIGKIGVVVGNCYGFVGNRMLAPYYNQGFFLLEE 238 Query: 516 GADPYLIDRAISKFGMPMGPFRLCDLVGFGVAIATA-------------TQFIENFSERT 562 G+ P +D + +FG MGPFR+ DL G V T + + R Sbjct: 239 GSKPEDVDGVLEEFGFKMGPFRVSDLAGLDVGWKIRKGQGLTGPSLPPGTPVRKRGNSRY 298 Query: 563 YKSMIIPLMQEDKRAGEATRKGFYLYDDK--RKAKPDPELKKYIEKARSISGVKLDPKLA 620 S + ++ E R G+ T KG+Y YD R KPDP L ++ + R + ++ Sbjct: 299 --SPLGDMLCEAGRFGQKTGKGWYQYDKPLGRIHKPDPWLSTFLSQYREVHHIEQ----R 352 Query: 621 NLSEKDIIEMTFFPVVNEACRVFAEGIAVKAADLDIAGIMGMGFPPYRGGIMFWADSIGS 680 +S+++I+E + ++NEA R+ EG+A + +D+ + G G+P ++GG MF+A S+G Sbjct: 353 TISKEEILERCLYSLINEAFRILEEGMAARPEHIDVIYLHGYGWPRHKGGPMFYAASVGL 412 Query: 681 KYIYSRLDEWSKAYGE--FFKPCAFLAERGSKGVLLSAPVKQASS 723 + +L ++ + + +P +L ++G S P+K+ S Sbjct: 413 PTVLEKLQKYYRQNPDIPQLEPSDYLRRLVAQG---SPPLKEWQS 454 >3K6J-A nrPDB Length = 460 Score = 417 bits (1071), Expect = e-116, Method: Composition-based stats. Identities = 136/415 (32%), Positives = 211/415 (50%), Gaps = 19/415 (4%) Query: 288 HVFFSQRGTAKVPGVTDRG----LVPRKIKKVAIIGGGLMGSGIATALILSNYPVILKEV 343 ++ + + DRG + VAIIGGG MG +A L+ L Sbjct: 26 YLMEAHSLAGQWSLPNDRGDHTNSEAYDVNSVAIIGGGTMGKAMAICFGLAGIETFLVVR 85 Query: 344 NEKFLEAGIGRVKANLQSRVRKGSMSQEKFEKTMSLLKGSLDYESFRDVDMVIEAVIENI 403 NE+ + + + A +S R ++ ++ EK + LK + D+ + D+++E+VIE++ Sbjct: 86 NEQRCKQELEVMYAREKSFKR---LNDKRIEKINANLKITSDFHKLSNCDLIVESVIEDM 142 Query: 404 SLKQQIFADLEKYCPQHCILASNTSTIDLNKIGERTKSQDRIVGAHFFSPAHIMPLLEIV 463 LK+++FA+LE C CI +NTS++DLN+I + +VG HFF+PA+++ L+EI+ Sbjct: 143 KLKKELFANLENICKSTCIFGTNTSSLDLNEISSVLRDPSNLVGIHFFNPANVIRLVEII 202 Query: 464 RTNHTSAQVIVDLLDVGKKIKKTPVVVGNCTGFAVNRMFFPYTQA-AMFLVECGADPYLI 522 +HTS+Q I + IKK PV+VGNC F NR+ Y + E G P+ I Sbjct: 203 YGSHTSSQAIATAFQACESIKKLPVLVGNCKSFVFNRLLHVYFDQSQKLMYEYGYLPHQI 262 Query: 523 DRAISKFGMPMGPFRLCDLVGFGVAIATATQFIENFSERTYKSMIIPLMQEDKRAGEATR 582 D+ I+ FG MGP + D+ GF V EN E + I M KR G T Sbjct: 263 DKIITNFGFLMGPMTVADMNGFDVMEKLKK---ENGLEP---NPIEKEMWRLKRYGRKTN 316 Query: 583 KGFYLYDDKRKAKP-DPELKKYIEKARSISGVKLDPKLANLSEKDIIEMTFFPVVNEACR 641 KGFY YDDK + K D E+++ I R K + ++ N ++D+I +P VNE R Sbjct: 317 KGFYKYDDKTQRKENDTEMEQIIR--RVSQNAKSNIQIIN--DQDVINFMLYPTVNEGYR 372 Query: 642 VFAEGIAVKAADLDIAGIMGMGFPPYRGGIMFWADSIGSKYIYSRLDEWSKAYGE 696 EG+ + +DI I+G G+P + GG M + + G I + L WS + Sbjct: 373 CIEEGVISNESLIDIMFILGFGWPIHSGGPMRFGKTEGLDKIANMLVHWSSLEPK 427 >3MOG-A nrPDB Length = 483 Score = 390 bits (1002), Expect = e-108, Method: Composition-based stats. Identities = 126/468 (26%), Positives = 209/468 (44%), Gaps = 74/468 (15%) Query: 311 KIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQ 370 ++ VA+IG G MG+GIA + V+L +++ + L I + A L SRV +G ++ Sbjct: 4 NVQTVAVIGSGTMGAGIAEVAASHGHQVLLYDISAEALTRAIDGIHARLNSRVTRGKLTA 63 Query: 371 EKFEKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADLEKYCPQHCILASNTSTI 430 E E+T+ L D + D+VIEA E + +K+ +FA L + CP +L +NTS+I Sbjct: 64 ETCERTLKRLIPVTDIHALAAADLVIEAASERLEVKKALFAQLAEVCPPQTLLTTNTSSI 123 Query: 431 DLNKIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDVGKKIKKTPVVV 490 + I K+ +R+ G HFF+PA +M L+E+V T+A+V+ L ++ K PV Sbjct: 124 SITAIAAEIKNPERVAGLHFFNPAPVMKLVEVVSGLATAAEVVEQLCELTLSWGKQPVRC 183 Query: 491 GNCTGFAVNRMFFPYTQAAMFLVEC-GADPYLIDRAIS-KFGMPMGPFRLCDLVGFGVAI 548 + GF VNR+ PY A +E A P +ID A+ G PMGP L DL+G V Sbjct: 184 HSTPGFIVNRVARPYYSEAWRALEEQVAAPEVIDAALRDGAGFPMGPLELTDLIGQDVNF 243 Query: 549 AT-ATQFIENFSERTYKSMII-PLMQEDKRAGEATRKGFYLYDDK--------------- 591 A + F + ER + ++ + R G+ + G Y + + Sbjct: 244 AVTCSVFNAFWQERRFLPSLVQQELVIGGRLGKKSGLGVYDWRAEREAVVGLEAVSDSFS 303 Query: 592 --------------------------------RKAKPDPELKKYIEKARSISGVKLDPKL 619 R A+P + K K +I+ ++P Sbjct: 304 PMKVEKKSDGVTEIDDVLLIETQGETAQALAIRLARPVVVIDKMAGKVVTIAAAAVNPDS 363 Query: 620 ANLSE--------KDIIEMTFFP----------VVNEACRVFAEGIAVKAADLDIAGIMG 661 A K ++++ +P ++NEA +G+A + D+D A +G Sbjct: 364 ATRKAIYYLQQQGKTVLQIADYPGMLIWRTVAMIINEALDALQKGVASE-QDIDTAMRLG 422 Query: 662 MGFPPYRGGIMFWADSIGSKYIYSRLDEWSKAYG-EFFKPCAFLAERG 708 + +P G + W +G + I L+ YG E ++PC+ L +R Sbjct: 423 VNYP---YGPLAWGAQLGWQRILRLLENLQHHYGEERYRPCSLLRQRA 467 Score = 53.2 bits (126), Expect = 4e-07, Method: Composition-based stats. Identities = 65/408 (15%), Positives = 122/408 (29%), Gaps = 33/408 (8%) Query: 171 KPVKAEEGHSLGLIDAVVPPA-ELVTTARRWALDIVGRRKPWVSSVSKTDKLPPLGEARE 229 + + + H+L D V+ A E + + + P + T + A E Sbjct: 72 RLIPVTDIHALAAADLVIEAASERLEVKKALFAQLAEVCPPQTLLTTNTSSISITAIAAE 131 Query: 230 ILTFAKAQTLKRAPNMKHPLMCLDAIEVGIVSGPRAGLEKEAEVASQVVKLDTTKGLIHV 289 I + L P+M L + G+ + +E+ E+ K Sbjct: 132 IKNPERVAGLHFFN--PAPVMKLVEVVSGLATAAEV-VEQLCELTLSWGKQPVRCHSTPG 188 Query: 290 FFSQRGTAKVPGVTDRGL-----VPRKIKKVAIIGGGL-MGSGIATALILSNYPVILKEV 343 F R R L P I G G MG L V Sbjct: 189 FIVNRVARPYYSEAWRALEEQVAAPEVIDAALRDGAGFPMGP--LELTDLIGQDVNFAVT 246 Query: 344 NEKFLEAGIGRVKANLQSRVRKGSMSQEKFEKTMSLLKGSLDYESFRDVDMVIEAVIENI 403 F + + L S V++ + + K L G D+ + R+ + +EAV ++ Sbjct: 247 CSVF--NAFWQERRFLPSLVQQELVIGGRLGKKSGL--GVYDWRAEREAVVGLEAVSDSF 302 Query: 404 SLKQQIFADLEKYCPQHCILASNTSTIDLNKIGERTKSQ----DRIVGAHFFSPAHIMPL 459 S ++ + +L T + R D++ G + Sbjct: 303 S-PMKVEKKSDGVTEIDDVLLIETQGETAQALAIRLARPVVVIDKMAG----------KV 351 Query: 460 LEIVRTNHTSAQVIVDLLDVGKKIKKTPVVVGNCTGFAVNRMFFPYTQAAMFLVECGADP 519 + I + ++ KT + + + G + R A+ ++ G Sbjct: 352 VTIAAAAVNPDSATRKAIYYLQQQGKTVLQIADYPGMLIWRTVAMIINEALDALQKGVAS 411 Query: 520 Y-LIDRAIS-KFGMPMGPFRLCDLVGFGVAIATATQFIENFSERTYKS 565 ID A+ P GP +G+ + ++ E Y+ Sbjct: 412 EQDIDTAMRLGVNYPYGPLAWGAQLGWQRILRLLENLQHHYGEERYRP 459 >6ACQ-A nrPDB Length = 302 Score = 356 bits (914), Expect = 2e-98, Method: Composition-based stats. Identities = 98/290 (33%), Positives = 156/290 (53%), Gaps = 5/290 (1%) Query: 306 GLVPR--KIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRV 363 GLVPR +KKV +IG G MGSGIA A + V+L+++ ++F++ G+ + NL V Sbjct: 13 GLVPRGSHMKKVCVIGAGTMGSGIAQAFAAKGFEVVLRDIKDEFVDRGLDFINKNLSKLV 72 Query: 364 RKGSMSQEKFEKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADLEKYCPQHCIL 423 +KG + + + ++ + G++D D D+VIEA +E + +K+QIFADL+ C IL Sbjct: 73 KKGKIEEATKVEILTRISGTVDLNMAADCDLVIEAAVERMDIKKQIFADLDNICKPETIL 132 Query: 424 ASNTSTIDLNKIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDVGKKI 483 ASNTS++ + ++ TK D+++G HFF+PA +M L+E++R TS + + + I Sbjct: 133 ASNTSSLSITEVASATKRPDKVIGMHFFNPAPVMKLVEVIRGIATSQETFDAVKETSIAI 192 Query: 484 KKTPVVVGNCTGFAVNRMFFPYTQAAMFLVECG-ADPYLIDRAIS-KFGMPMGPFRLCDL 541 K PV V GF VNR+ P A+ ++ G A ID+A+ PMGP L D Sbjct: 193 GKDPVEVAEAPGFVVNRILIPMINEAVGILAEGIASVEDIDKAMKLGANHPMGPLELGDF 252 Query: 542 VGFGVAIATATQFIENFSERTYKSM-IIPLMQEDKRAGEATRKGFYLYDD 590 +G + +A + Y+ ++ G + KGFY Y Sbjct: 253 IGLDICLAIMDVLYSETGDSKYRPHTLLKKYVRAGWLGRKSGKGFYDYSK 302 Score = 55.9 bits (133), Expect = 6e-08, Method: Composition-based stats. Identities = 26/106 (24%), Positives = 43/106 (40%), Gaps = 5/106 (4%) Query: 609 SISGVKLDPKLANLSEKDIIEMTFFPVVNEACRVFAEGIAVKAADLDIAGIMGMGFPPYR 668 + + DP + ++ P++NEA + AEGIA D+D A +G P Sbjct: 188 TSIAIGKDPVEVAEAPGFVVNRILIPMINEAVGILAEGIAS-VEDIDKAMKLGANHPM-- 244 Query: 669 GGIMFWADSIGSKYIYSRLDEWSKAYGE-FFKPCAFLAERGSKGVL 713 G + D IG + +D G+ ++P L + G L Sbjct: 245 -GPLELGDFIGLDICLAIMDVLYSETGDSKYRPHTLLKKYVRAGWL 289 >4KUG-A nrPDB Length = 290 Score = 349 bits (895), Expect = 3e-96, Method: Composition-based stats. Identities = 97/284 (34%), Positives = 156/284 (54%), Gaps = 3/284 (1%) Query: 312 IKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQE 371 +KKV ++G G MG+GI A VI++++ E+F++ GI + +L V K +++ Sbjct: 1 MKKVFVLGAGTMGAGIVQAFAAKGCEVIVRDIKEEFVDRGIATITKSLSKLVAKEKITEA 60 Query: 372 KFEKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADLEKYCPQHCILASNTSTID 431 E+ +S + G+ D + D D+V+EA IEN+ +K++IFA+L+ C ILASNTS++ Sbjct: 61 DKEEILSRISGTTDMKLAADCDLVVEAAIENMKIKKEIFAELDGICKPETILASNTSSLS 120 Query: 432 LNKIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDVGKKIKKTPVVVG 491 + ++ TK D+++G HFF+PA +M L+E++R TS + + ++ + I KTPV V Sbjct: 121 ITEVASATKRADKVIGMHFFNPAPVMKLVEVIRGAATSQETFDAVKEMSESIGKTPVEVA 180 Query: 492 NCTGFAVNRMFFPYTQAAMFLVECG-ADPYLIDRAIS-KFGMPMGPFRLCDLVGFGVAIA 549 GF VNR+ P A F+++ G A ID A+ PMGP L DL+G V +A Sbjct: 181 EAPGFVVNRILIPMINEATFILQEGVAKEEDIDAAMKLGANHPMGPLALGDLIGLDVCLA 240 Query: 550 TATQFIENFSERTYK-SMIIPLMQEDKRAGEATRKGFYLYDDKR 592 + Y+ S ++ G T KGFY Y + Sbjct: 241 IMDVLYNETGDTKYRASSLLRKYVRAGWLGRKTGKGFYDYSKSK 284 Score = 57.4 bits (137), Expect = 2e-08, Method: Composition-based stats. Identities = 26/138 (18%), Positives = 51/138 (36%), Gaps = 12/138 (8%) Query: 584 GFYLYDDKRKAKPDPELKKYIEKARSISGVKLDPKLANLSEKDI-------IEMTFFPVV 636 G + ++ K ++ + VK + + ++ + P++ Sbjct: 136 GMHFFNPAPVMKLVEVIRGAATSQETFDAVKEMSESIGKTPVEVAEAPGFVVNRILIPMI 195 Query: 637 NEACRVFAEGIAVKAADLDIAGIMGMGFPPYRGGIMFWADSIGSKYIYSRLDEWSKAYGE 696 NEA + EG+A K D+D A +G P G + D IG + +D G+ Sbjct: 196 NEATFILQEGVA-KEEDIDAAMKLGANHPM---GPLALGDLIGLDVCLAIMDVLYNETGD 251 Query: 697 -FFKPCAFLAERGSKGVL 713 ++ + L + G L Sbjct: 252 TKYRASSLLRKYVRAGWL 269 >1F14-A nrPDB Length = 310 Score = 336 bits (862), Expect = 2e-92, Method: Composition-based stats. Identities = 99/288 (34%), Positives = 148/288 (51%), Gaps = 10/288 (3%) Query: 312 IKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKG----- 366 +K V +IGGGLMG+GIA + + V+L + E L ++ +L+ +K Sbjct: 15 VKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENP 74 Query: 367 SMSQEKFEKTMSLLKGSLDYESF-RDVDMVIEAVIENISLKQQIFADLEKYCPQHCILAS 425 E EKT+S + S D S D+V+EA++EN+ +K ++F L+K+ +H I AS Sbjct: 75 KAGDECVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFAS 134 Query: 426 NTSTIDLNKIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDVGKKIKK 485 NTS++ + I T QDR G HFF+P +M L+E+++T TS + L+D K + K Sbjct: 135 NTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGK 194 Query: 486 TPVVVGNCTGFAVNRMFFPYTQAAMFLVECG-ADPYLIDRAIS-KFGMPMGPFRLCDLVG 543 PV + GF VNR+ PY A+ L E G A ID A+ G PMGPF L D VG Sbjct: 195 HPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYPMGPFELLDYVG 254 Query: 544 FGVAIATATQFIENFSER--TYKSMIIPLMQEDKRAGEATRKGFYLYD 589 + E +E S + + + + G+ T +GFY Y Sbjct: 255 LDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKYK 302 Score = 49.7 bits (117), Expect = 4e-06, Method: Composition-based stats. Identities = 25/117 (21%), Positives = 42/117 (35%), Gaps = 6/117 (5%) Query: 596 PDPELKKYIEKARSISGVKLDPKLANLSEKDIIEMTFFPVVNEACRVFAEGIAVKAADLD 655 P K + + P + I+ P + EA R++ G A K D+D Sbjct: 175 PMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASK-EDID 233 Query: 656 IAGIMGMGFPPYRGGIMFWADSIGSKYIYSRLDEWSKAYGE--FFKPCAFLAERGSK 710 A +G G+P G D +G +D W + E +P L + ++ Sbjct: 234 TAMKLGAGYPM---GPFELLDYVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAE 287 >4J0E-A nrPDB Length = 320 Score = 335 bits (858), Expect = 5e-92, Method: Composition-based stats. Identities = 95/291 (32%), Positives = 148/291 (50%), Gaps = 9/291 (3%) Query: 310 RKIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMS 369 + I+ VAI+G G MGSGIA S + V+L +VN+K L+ + + ++ +K + Sbjct: 12 QNIRNVAIVGSGQMGSGIAQVTASSGFNVMLADVNKKALDRAMKAISQSVTHLSKKQKGT 71 Query: 370 QEKFEK----TMSLLKGSLDYE-SFRDVDMVIEAVIENISLKQQIFADLEKYCPQHCILA 424 ++ TMS +K + + D D++IEA IENI LK+ IFA +E+ C + IL Sbjct: 72 DKEKSDFVTLTMSRIKTCNNVSTAVADADLIIEAAIENIDLKRGIFAQIEQSCKKDSILT 131 Query: 425 SNTSTIDLNKIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDVGKKIK 484 +NTS+ L + + + + R G HFF+P +M LLE++R++ TS + L+ G + Sbjct: 132 TNTSSFLLEDVAKGLQDKTRFGGLHFFNPVPVMKLLEVIRSDDTSDETYATLIKFGTAVG 191 Query: 485 KTPVVVGNCTGFAVNRMFFPYTQAAMFLVECG-ADPYLIDRAIS-KFGMPMGPFRLCDLV 542 KT V + GF VNR+ PY A + E G A ID A+ G PMGPF L D + Sbjct: 192 KTTVACKDSPGFIVNRLLIPYFFEAARMYERGDASMTDIDEAMKLGAGHPMGPFELADYI 251 Query: 543 GFGVAIATATQFIENFSERTY--KSMIIPLMQEDKRAGEATRKGFYLYDDK 591 G + + E S ++ + + + G T GFY Y + Sbjct: 252 GLDTVKFVMDGWAAKYPEVQLFEASPLVDKLVAEGKLGRKTGDGFYSYKKE 302 Score = 54.7 bits (130), Expect = 1e-07, Method: Composition-based stats. Identities = 25/89 (28%), Positives = 38/89 (42%), Gaps = 6/89 (6%) Query: 627 IIEMTFFPVVNEACRVFAEGIAVKAADLDIAGIMGMGFPPYRGGIMFWADSIGSKYIYSR 686 I+ P EA R++ G A D+D A +G G P G AD IG + Sbjct: 204 IVNRLLIPYFFEAARMYERGDASMT-DIDEAMKLGAGHPM---GPFELADYIGLDTVKFV 259 Query: 687 LDEWSKAYGE--FFKPCAFLAERGSKGVL 713 +D W+ Y E F+ + + ++G L Sbjct: 260 MDGWAAKYPEVQLFEASPLVDKLVAEGKL 288 >3HDH-A nrPDB Length = 302 Score = 332 bits (851), Expect = 3e-91, Method: Composition-based stats. Identities = 98/292 (33%), Positives = 151/292 (51%), Gaps = 18/292 (6%) Query: 312 IKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKG----- 366 +K V +IGGGLMG+GIA + + V+L + E L ++ +L+ +K Sbjct: 15 VKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENP 74 Query: 367 SMSQEKFEKTMSLLKGSLDYESF-RDVDMVIEAVIENISLKQQIFADLEKYCPQHCILAS 425 E EKT+S + S D S D+V+EA++EN+ +K ++F L+K+ +H I AS Sbjct: 75 KAGDEFVEKTLSSISTSTDAASVVHSTDLVVEAIVENLKVKSELFKRLDKFAAEHTIFAS 134 Query: 426 NTSTIDLNKIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDVGKKIKK 485 NTS++ + + T QDR G HFF+P +M L+E+V+T TS + + L+D K + K Sbjct: 135 NTSSLQITSLANATTRQDRFAGLHFFNPVPLMKLVEVVKTPMTSQKTLESLVDFSKTLGK 194 Query: 486 TPVVVGNCTGFAVNRMFFPYTQAAMFLVECG-ADPYLIDRAIS-KFGMPMGPFRLCDLVG 543 PV + GF VNR+ PY A+ L E G A ID A+ G PMGPF L D VG Sbjct: 195 HPVSCKDTPGFIVNRLLVPYLIEAVRLYERGDASKEDIDTAMKLGAGYPMGPFELLDYVG 254 Query: 544 FGVAIATATQFIENFSERTYKSMI------IPLMQEDKRAGEATRKGFYLYD 589 I+ + E ++ + + + + + G+ T +GFY Y Sbjct: 255 LDTTKFI----IDGWHEMDSQNPLFQPSPAMNKLVAENKFGKKTGEGFYKYK 302 Score = 49.3 bits (116), Expect = 6e-06, Method: Composition-based stats. Identities = 21/86 (24%), Positives = 37/86 (43%), Gaps = 6/86 (6%) Query: 627 IIEMTFFPVVNEACRVFAEGIAVKAADLDIAGIMGMGFPPYRGGIMFWADSIGSKYIYSR 686 I+ P + EA R++ G A K D+D A +G G+P G D +G Sbjct: 206 IVNRLLVPYLIEAVRLYERGDASK-EDIDTAMKLGAGYPM---GPFELLDYVGLDTTKFI 261 Query: 687 LDEWSKAYGE--FFKPCAFLAERGSK 710 +D W + + F+P + + ++ Sbjct: 262 IDGWHEMDSQNPLFQPSPAMNKLVAE 287 >4PZE-A nrPDB Length = 284 Score = 331 bits (848), Expect = 7e-91, Method: Composition-based stats. Identities = 85/282 (30%), Positives = 146/282 (51%), Gaps = 3/282 (1%) Query: 312 IKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQE 371 I+ V I+G G MG+GIA A + V++ ++++ ++ G+ V ++L ++K +++ Sbjct: 3 IRTVGIVGAGTMGNGIAQACAVVGLNVVMVDISDAAVQKGVATVASSLDRLIKKEKLTEA 62 Query: 372 KFEKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADLEKYCPQHCILASNTSTID 431 ++ +KGS Y+ + D+VIEA EN LK +I ++ ++ I+ASNTS+I Sbjct: 63 DKASALARIKGSTSYDDLKATDIVIEAATENYDLKVKILKQIDGIVGENVIIASNTSSIS 122 Query: 432 LNKIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDVGKKIKKTPVVVG 491 + K+ T DR +G HFF+P +M L+E++R TS + + K++ K P+ V Sbjct: 123 ITKLAAVTSRADRFIGMHFFNPVPVMALVELIRGLQTSDTTHAAVEALSKQLGKYPITVK 182 Query: 492 NCTGFAVNRMFFPYTQAAMFLVECG-ADPYLIDRAIS-KFGMPMGPFRLCDLVGFGVAIA 549 N GF VNR+ P A ++ G A P ID + P+GP L D++G +A Sbjct: 183 NSPGFVVNRILCPMINEAFCVLGEGLASPEEIDEGMKLGCNHPIGPLALADMIGLDTMLA 242 Query: 550 TATQFIENFSERTYKS-MIIPLMQEDKRAGEATRKGFYLYDD 590 F++ Y+ M++ M G T +G Y+Y Sbjct: 243 VMEVLYTEFADPKYRPAMLMREMVAAGYLGRKTGRGVYVYSK 284 Score = 61.6 bits (148), Expect = 1e-09, Method: Composition-based stats. Identities = 32/170 (18%), Positives = 59/170 (34%), Gaps = 24/170 (14%) Query: 546 VAIATATQFIENFSERTYKSMIIPL-MQEDKRAGEATRKGFYLYDDKRKAKPDPELKKYI 604 +A T + F + + + + + E R G T L K + Sbjct: 124 TKLAAVTSRADRFIGMHFFNPVPVMALVELIR-GLQT--------SDTTHAAVEALSKQL 174 Query: 605 EKARSISGVKLDPKLANLSEKDIIEMTFFPVVNEACRVFAEGIAVKAADLDIAGIMGMGF 664 K P S ++ P++NEA V EG+A ++D +G Sbjct: 175 GKY---------PITVKNSPGFVVNRILCPMINEAFCVLGEGLAS-PEEIDEGMKLGCNH 224 Query: 665 PPYRGGIMFWADSIGSKYIYSRLDEWSKAYGE-FFKPCAFLAERGSKGVL 713 P G + AD IG + + ++ + + ++P + E + G L Sbjct: 225 PI---GPLALADMIGLDTMLAVMEVLYTEFADPKYRPAMLMREMVAAGYL 271 >6HRD-A nrPDB Length = 317 Score = 310 bits (794), Expect = 1e-84, Method: Composition-based stats. Identities = 99/296 (33%), Positives = 156/296 (52%), Gaps = 11/296 (3%) Query: 306 GLVPR------KIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANL 359 GLVPR I++V ++G G MGSGIA + V + E E + AG R+ +L Sbjct: 13 GLVPRGSHMSDAIQRVGVVGAGQMGSGIAEVSARAGVEVTVFEPAEALITAGRNRIVKSL 72 Query: 360 QSRVRKGSMSQEKFEKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADLEKYC-P 418 + V G +++ + ++ + LL + D D +VIEAV+E+ ++K +IFA+L++ Sbjct: 73 ERAVSAGKVTERERDRALGLLTFTTDLNDLSDRQLVIEAVVEDEAVKSEIFAELDRVVTD 132 Query: 419 QHCILASNTSTIDLNKIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLD 478 +LASNTS+I + K+ TK R++G HFF+P ++PL+E+VRT T + Sbjct: 133 PDAVLASNTSSIPIMKVAAATKQPQRVLGLHFFNPVPVLPLVELVRTLVTDEAAAARTEE 192 Query: 479 VGKKI-KKTPVVVGNCTGFAVNRMFFPYTQAAMFLVECG-ADPYLIDRA-ISKFGMPMGP 535 + K V + +GF VN + PY +A+ +VE G A +D+A ++ PMGP Sbjct: 193 FASTVLGKQVVRCSDRSGFVVNALLVPYLLSAIRMVEAGFATVEDVDKAVVAGLSHPMGP 252 Query: 536 FRLCDLVGFGVAIATATQFIENFSERTY-KSMIIPLMQEDKRAGEATRKGFYLYDD 590 RL DLVG A + E F E Y ++ M E + G+ + +GFY Y Sbjct: 253 LRLSDLVGLDTLKLIADKMFEEFKEPHYGPPPLLLRMVEAGQLGKKSGRGFYTYAA 308 >1ZEJ-A nrPDB Length = 293 Score = 278 bits (711), Expect = 6e-75, Method: Composition-based stats. Identities = 83/297 (27%), Positives = 138/297 (46%), Gaps = 27/297 (9%) Query: 314 KVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEKF 373 KV +IG GLMG GIA A+ + V+L++V+EK LEA ++ Sbjct: 14 KVFVIGAGLMGRGIAIAIASK-HEVVLQDVSEKALEAAREQIP----------------- 55 Query: 374 EKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADLEKYCPQHCILASNTSTIDLN 433 E+ +S ++ + E +D D+V+EAV E+++ K ++ ++E+ + L SNTS I ++ Sbjct: 56 EELLSKIEFTTTLEKVKDCDIVMEAVFEDLNTKVEVLREVERLT--NAPLCSNTSVISVD 113 Query: 434 KIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDVGKKIKKTPVVVGNC 493 I ER S R +G H+ +P H+MPL+EIV + T ++ + + +++ K VV Sbjct: 114 DIAERLDSPSRFLGVHWMNPPHVMPLVEIVISRFTDSKTVAFVEGFLRELGKEVVVCKGQ 173 Query: 494 TGFAVNRMFFPYTQAAMFLVECGADPYLIDRAI-SKFGM---PMGPFRLCDLVGFGVAIA 549 + VNR A ++E G +DR G+ GP D +G VA Sbjct: 174 S--LVNRFNAAVLSEASRMIEEGVRAEDVDRVWKHHLGLLYTLFGPLGNLDYIGLDVAYY 231 Query: 550 TATQFIENFSERTYKSM-IIPLMQEDKRAGEATRKGFYLYDDKRKAKPDPELKKYIE 605 + + F + +K + + G KG Y Y K + LKK + Sbjct: 232 ASLYLYKRFGDEKFKPPEWLQEKIKKGEVGVKAGKGIYEYGPKAYEERVERLKKLLR 288 Score = 45.1 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 25/99 (25%), Positives = 43/99 (43%), Gaps = 3/99 (3%) Query: 614 KLDPKLANLSEKDIIEMTFFPVVNEACRVFAEGIAVKAADLDIAGIMGMGFPPYRGGIMF 673 +L ++ + ++ V++EA R+ EG+ +A D+D +G G + Sbjct: 162 ELGKEVVVCKGQSLVNRFNAAVLSEASRMIEEGV--RAEDVDRVWKHHLGLLYTLFGPLG 219 Query: 674 WADSIGSKYIYSRLDEWSKAYGE-FFKPCAFLAERGSKG 711 D IG Y K +G+ FKP +L E+ KG Sbjct: 220 NLDYIGLDVAYYASLYLYKRFGDEKFKPPEWLQEKIKKG 258 >4OM8-A nrPDB Length = 309 Score = 269 bits (688), Expect = 3e-72, Method: Composition-based stats. Identities = 78/310 (25%), Positives = 139/310 (44%), Gaps = 10/310 (3%) Query: 312 IKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQE 371 I+ +AIIG G MG G+A L V+ +V +E + G Sbjct: 2 IRNIAIIGLGTMGPGMAARLARGGLQVVAYDVAPAAIERARSMLSVAETVLDALGIALPS 61 Query: 372 KFEKTMSLLKGSLDYES-FRDVDMVIEAVIENISLKQQIFADLEKYCPQHCILASNTSTI 430 + ++ + D D+VIE V ENIS+K ++ ++ Q I+AS+TS I Sbjct: 62 AG---VGTVRFTDDIGDAVSGADLVIENVPENISIKADVYRTIDGLIGQDTIVASDTSGI 118 Query: 431 DLNKIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDVGKKIKKTPVVV 490 + K+ +R+VG H+ +P HI+P++E++ T+ Q + + D+ + I PVVV Sbjct: 119 PITKLQAHISYPERMVGMHWSNPPHIIPMIEVIAGEKTAPQTVATIRDLIRSIGLLPVVV 178 Query: 491 -GNCTGFAVNRMFFPYTQAAMFLVECGA-DPYLIDRAIS-KFGMP---MGPFRLCDLVGF 544 + GF NR+ + + A+ LVE G DP +D +S G +GP L D+ G Sbjct: 179 KKDVPGFVENRVLYALLREAVDLVERGVIDPEDLDTCVSWGIGYKIAVIGPMALLDMAGL 238 Query: 545 GVAIATATQFIENFSERTYKSMIIPLMQEDKRAGEATRKGFYLYDDKRKAKPDPELKKYI 604 + + ++ + S R + ++ + G + +G + Y ++ E + + Sbjct: 239 DIYKSVSSFLNADLSNRDDVAPMVLEKTSASKFGIKSGEGMFCYTPEQTKALQAERARKL 298 Query: 605 EKARSISGVK 614 R I + Sbjct: 299 VAVRRILEGR 308 Score = 39.3 bits (90), Expect = 0.006, Method: Composition-based stats. Identities = 12/55 (21%), Positives = 20/55 (36%), Gaps = 1/55 (1%) Query: 627 IIEMTFFPVVNEACRVFAEGIAVKAADLDIAGIMGMGFPPYRGGIMFWADSIGSK 681 + + ++ EA + G+ DLD G+G+ G M D G Sbjct: 186 VENRVLYALLREAVDLVERGVI-DPEDLDTCVSWGIGYKIAVIGPMALLDMAGLD 239 >4DYD-A nrPDB Length = 283 Score = 268 bits (685), Expect = 6e-72, Method: Composition-based stats. Identities = 75/283 (26%), Positives = 134/283 (47%), Gaps = 9/283 (3%) Query: 312 IKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVK--ANLQSRVRKGSMS 369 I V ++G G++GS IA + V ++N L+A R + A + + G+ + Sbjct: 4 ITNVTVLGTGVLGSQIAFQTAFHGFAVTAYDINTDALDAAKKRFEGLAAVYEKEVAGA-A 62 Query: 370 QEKFEKTMSLLKGSLDY-ESFRDVDMVIEAVIENISLKQQIFADLEKYCPQHCILASNTS 428 +K + ++ S D ++ +D D+VIEAV E++ LK+ I+ L + P I A+N+S Sbjct: 63 DGAAQKALGGIRYSDDLAQAVKDADLVIEAVPESLDLKRDIYTKLGELAPAKTIFATNSS 122 Query: 429 TIDLNKIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDVGKKIKKTPV 488 T+ + + T D+ + HF + + E++ T T +V +++ I P+ Sbjct: 123 TLLPSDLVGYTGRGDKFLALHFANHVWVNNTAEVMGTTKTDPEVYQQVVEFASAIGMVPI 182 Query: 489 VV-GNCTGFAVNRMFFPYTQAAM-FLVECGADPYLIDRAIS-KFGMPMGPFRLCDLVGFG 545 + G+ +N + P AA LV+ ADP ID+ G P GPF + D+VG Sbjct: 183 ELKKEKAGYVLNSLLVPLLDAAAELLVDGIADPETIDKTWRIGTGAPKGPFEIFDIVGLT 242 Query: 546 VAIATATQFIENFSERTYKSMIIPLMQEDKRAGEATRKGFYLY 588 A ++ +R + + + + + G AT +GFY Y Sbjct: 243 TAYNISSV--SGPKQREFAAYLKENYIDKGKLGLATGEGFYRY 283 >3F3S-A nrPDB Length = 313 Score = 255 bits (651), Expect = 6e-68, Method: Composition-based stats. Identities = 64/254 (25%), Positives = 117/254 (46%), Gaps = 13/254 (5%) Query: 315 VAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQE-KF 373 V I+G G++G A + V L ++ ++ + + ++ ++ + GS+ Sbjct: 6 VVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQAGSLKGSLSV 65 Query: 374 EKTMSLLKGSLDYESFRDVDMVI-EAVIENISLKQQIFADLEKYCPQHCILASNTSTIDL 432 E+ +SL+ G + + + M I E V E++ LK++IFA L+ IL+S+TS + Sbjct: 66 EEQLSLISGCPNIQEAVEGAMHIQECVPEDLELKKKIFAQLDSIIDDRVILSSSTSCLMP 125 Query: 433 NKIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDVGKKIKKTPV-VVG 491 +K+ + + AH +P + +PL+E+V T+ + + KKI + P+ V Sbjct: 126 SKLFAGLVHVKQCIVAHPVNPPYYIPLVELVPHPETAPTTVDRTHALMKKIGQCPMRVQK 185 Query: 492 NCTGFAVNRMFFPYTQAAMFLVECG-ADPYLIDRAIS-KFGMP---MGPFRLCDLVGFGV 546 GF +NR+ + A LVE G P +D +S GM +GP L G Sbjct: 186 EVAGFVLNRLQYAIISEAWRLVEEGIVSPSDLDLVMSEGLGMRYAFIGPLETMHLNAEG- 244 Query: 547 AIATATQFIENFSE 560 + + +SE Sbjct: 245 ----MLSYCDRYSE 254 >3ADO-A nrPDB Length = 319 Score = 231 bits (588), Expect = 1e-60, Method: Composition-based stats. Identities = 65/258 (25%), Positives = 119/258 (46%), Gaps = 13/258 (5%) Query: 315 VAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQE-KF 373 V I+G GL+G A + V L ++ + + + ++ ++S + GS+ Sbjct: 9 VLIVGSGLVGRSWAMLFASGGFRVKLYDIEPRQITGALENIRKEMKSLQQSGSLKGSLSA 68 Query: 374 EKTMSLLKGSLDY-ESFRDVDMVIEAVIENISLKQQIFADLEKYCPQHCILASNTSTIDL 432 E+ +SL+ + E+ V + E V EN+ LK++IFA L+ +L+S++S + Sbjct: 69 EEQLSLISSCTNLAEAVEGVVHIQECVPENLDLKRKIFAQLDSIVDDRVVLSSSSSCLLP 128 Query: 433 NKIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDVGKKIKKTPV-VVG 491 +K+ + + AH +P + +PL+E+V TS + + +KI ++PV V+ Sbjct: 129 SKLFTGLAHVKQCIVAHPVNPPYYIPLVELVPHPETSPATVDRTHALMRKIGQSPVRVLK 188 Query: 492 NCTGFAVNRMFFPYTQAAMFLVECG-ADPYLIDRAIS-KFGMP---MGPFRLCDLVGFGV 546 GF +NR+ + A LVE G P +D +S GM +GP L G Sbjct: 189 EIDGFVLNRLQYAIISEAWRLVEEGIVSPSDLDLVMSDGLGMRYAFIGPLETMHLNAEG- 247 Query: 547 AIATATQFIENFSERTYK 564 + + +SE + Sbjct: 248 ----MLSYCDRYSEGMKR 261 >2IEX-A nrPDB Length = 272 Score = 229 bits (585), Expect = 2e-60, Method: Composition-based stats. Identities = 56/199 (28%), Positives = 95/199 (47%), Gaps = 4/199 (2%) Query: 16 DGVAVITLINPPV-NSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKG-RFSGGFDISGF 73 +G+A IT+ P V N+ + + + +A +++ I++TGA G F G D Sbjct: 20 NGIAKITINRPEVHNAFRPKTVNEMIDAFTKARDDSNIGVIILTGAGGKAFCSGGDQKVR 79 Query: 74 GEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAA 133 G G V E + +++ + L+ KP +A + G A+GGG L + C I+A A Sbjct: 80 G--HGGYVGEDEIPRLNVLDLQRLIRVIPKPVIAMVAGYAIGGGHVLHVVCDLTIAADNA 137 Query: 134 QLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAEL 193 G ++G G G L R+VG KA E+ + A+E +GL++ VVP +L Sbjct: 138 IFGQTGPKVGSFDGGYGAGYLARIVGHKKAREIWYLCRQYTAQEALEMGLVNKVVPLEQL 197 Query: 194 VTTARRWALDIVGRRKPWV 212 +WA +I+ + + Sbjct: 198 EEETVKWAQEILEKSPTAI 216 >3T88-A nrPDB Length = 289 Score = 227 bits (578), Expect = 2e-59, Method: Composition-based stats. Identities = 53/200 (26%), Positives = 90/200 (45%), Gaps = 3/200 (1%) Query: 12 EVGGDGVAVITLINPPV-NSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKG-RFSGGFD 69 E DG+A IT+ P V N+ + + +A +++ I++TGA F G D Sbjct: 32 EKSTDGIAKITINRPQVRNAFRPLTVKEMIQALADARYDDNIGVIILTGAGDKAFCSGGD 91 Query: 70 ISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARIS 129 G+ G + ++++ + KP VA + G ++GGG L M C I+ Sbjct: 92 QKVRGD-YGGYKDDSGVHHLNVLDFQRQIRTCPKPVVAMVAGYSIGGGHVLHMMCDLTIA 150 Query: 130 APAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVP 189 A A G ++G G G + R+VG KA E+ + A++ +GL++ VVP Sbjct: 151 ADNAIFGQTGPKVGSFDGGWGASYMARIVGQKKAREIWFLCRQYDAKQALDMGLVNTVVP 210 Query: 190 PAELVTTARRWALDIVGRRK 209 A+L RW +++ Sbjct: 211 LADLEKETVRWCREMLQNSP 230 >5ZAI-A nrPDB Length = 259 Score = 225 bits (574), Expect = 4e-59, Method: Composition-based stats. Identities = 78/209 (37%), Positives = 117/209 (55%), Gaps = 4/209 (1%) Query: 8 KTVMEVGGDGVAVITLINP-PVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSG 66 +T+ + ITL P +N+L+ +L L +A S +++ I+ITG F Sbjct: 4 ETIETKKEGNLFWITLNRPDKLNALNAKLLEELDRAVSQAESDPEIRVIIITGKGKAFCA 63 Query: 67 GFDISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHA 126 G DI+ F ++ E I D +EA KP++A I+G ALGGGLELA+AC Sbjct: 64 GADITQFNQLTPA---EAWKFSKKGREIMDKIEALSKPTIAMINGYALGGGLELALACDI 120 Query: 127 RISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDA 186 RI+A AQLGLPE+ LG+ PG+GGTQRL R++G +ALEM++T + ++ GL++ Sbjct: 121 RIAAEEAQLGLPEINLGIYPGYGGTQRLTRVIGKGRALEMMMTGDRIPGKDAEKYGLVNR 180 Query: 187 VVPPAELVTTARRWALDIVGRRKPWVSSV 215 VVP A L R+ A I + ++ + Sbjct: 181 VVPLANLEQETRKLAEKIAKKSPISLALI 209 >4EML-A nrPDB Length = 275 Score = 220 bits (560), Expect = 2e-57, Method: Composition-based stats. Identities = 52/207 (25%), Positives = 92/207 (44%), Gaps = 9/207 (4%) Query: 10 VMEVGGDGVAVITLINP-PVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGR----- 63 ++ G+A I + P N+ ++ L + A N + +++TGA Sbjct: 12 ILYYKAGGIAKIVINRPHKRNAFRPQTVFELYDAFCNAREDNRIGVVLLTGAGPHSDGKY 71 Query: 64 -FSGGFDISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAM 122 F G D S GE G + + +++ + L+ + K +A + G A+GGG L + Sbjct: 72 AFCSGGDQSVRGE--GGYIDDQGTPRLNVLDLQRLIRSMPKVVIALVAGYAIGGGHVLHL 129 Query: 123 ACHARISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLG 182 C I+A A G ++G G G+ L R+VG KA E+ + A+E +G Sbjct: 130 VCDLTIAADNAIFGQTGPKVGSFDGGFGSSYLARIVGQKKAREIWYLCRQYSAQEAERMG 189 Query: 183 LIDAVVPPAELVTTARRWALDIVGRRK 209 +++ VVP L +WA +I+ + Sbjct: 190 MVNTVVPVDRLEEEGIQWAKEILSKSP 216 >2UZF-A nrPDB Length = 273 Score = 219 bits (557), Expect = 4e-57, Method: Composition-based stats. Identities = 54/215 (25%), Positives = 95/215 (44%), Gaps = 10/215 (4%) Query: 6 KGKTVMEVGG------DGVAVITLINPPV-NSLSFDVLYNLKSNYEEALSRNDVKAIVIT 58 + +T+ E +G+A +T+ P V N+ + + + + A +V IV+T Sbjct: 5 QWETLREYDEIKYEFYEGIAKVTINRPEVRNAFTPKTVAEMIDAFSRARDDQNVSVIVLT 64 Query: 59 GAKG-RFSGGFDISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGG 117 G F G D G G V E + +++ + L+ KP +A + G A+GGG Sbjct: 65 GEGDLAFCSGGDQKKRG--HGGYVGEDQIPRLNVLDLQRLIRIIPKPVIAMVKGYAVGGG 122 Query: 118 LELAMACHARISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEE 177 L + C I+A A G ++G G+ L R+VG KA E+ + A+E Sbjct: 123 NVLNVVCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNAQE 182 Query: 178 GHSLGLIDAVVPPAELVTTARRWALDIVGRRKPWV 212 +GL++ VVP ++ +W +I+ + Sbjct: 183 ALDMGLVNTVVPLEKVEDETVQWCKEIMKHSPTAL 217 >2DUB-A nrPDB Length = 261 Score = 218 bits (554), Expect = 1e-56, Method: Composition-based stats. Identities = 73/198 (36%), Positives = 101/198 (51%), Gaps = 6/198 (3%) Query: 17 GVAVITLINPP-VNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGFGE 75 V +I L P +N+L ++ L E V AIV+TG + F+ G DI E Sbjct: 17 SVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIK---E 73 Query: 76 MQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAAQL 135 MQ ++ +G D + +KP +AA++G ALGGG ELAM C + AQ Sbjct: 74 MQNRTFQDCYSGKFLSH--WDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEKAQF 131 Query: 136 GLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAELVT 195 G PE+ LG IPG GGTQRL R VG + A+EM+LT + A++ GL+ + P LV Sbjct: 132 GQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETLVE 191 Query: 196 TARRWALDIVGRRKPWVS 213 A + A I K V+ Sbjct: 192 EAIQCAEKIANNSKIIVA 209 >5Z7R-A nrPDB Length = 267 Score = 215 bits (547), Expect = 7e-56, Method: Composition-based stats. Identities = 84/228 (36%), Positives = 125/228 (54%), Gaps = 5/228 (2%) Query: 10 VMEVGGDGVAVITLINPP-VNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAK-GRFSGG 67 V+ VAV+T+ P +N+L+ D L + E + ++V A+++TGA F G Sbjct: 6 VILEKEGKVAVVTINRPKALNALNSDTLKEMDYVIGEIENDSEVLAVILTGAGEKSFVAG 65 Query: 68 FDISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHAR 127 DIS EM N E + I + + LE KP +AA++G ALGGG E+AM+C R Sbjct: 66 ADISEMKEM---NTIEGRKFGILGNKVFRRLELLEKPVIAAVNGFALGGGCEIAMSCDIR 122 Query: 128 ISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAV 187 I++ A+ G PE+ LG+ PGFGGTQRL RLVG+ A ++I T++ +KA+E +GL++ V Sbjct: 123 IASSNARFGQPEVGLGITPGFGGTQRLSRLVGMGMAKQLIFTAQNIKADEALRIGLVNKV 182 Query: 188 VPPAELVTTARRWALDIVGRRKPWVSSVSKTDKLPPLGEAREILTFAK 235 V P+EL+ TA+ A IV V + + L F Sbjct: 183 VEPSELMNTAKEIANKIVSNAPVAVKLSKQAINRGMQCDIDTALAFES 230 >2HW5-A nrPDB Length = 286 Score = 211 bits (536), Expect = 1e-54, Method: Composition-based stats. Identities = 69/201 (34%), Positives = 99/201 (49%), Gaps = 6/201 (2%) Query: 14 GGDGVAVITLINPP-VNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISG 72 + V +I L P +N+L ++ L + V AIV+TG F+ G DI Sbjct: 39 KNNTVGLIQLNRPKALNALCDGLIDELNQALKIFEEDPAVGAIVLTGGDKAFAAGADIK- 97 Query: 73 FGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPA 132 EMQ + ++ + D L +KP +AA++G A GGG ELAM C + Sbjct: 98 --EMQNLSFQDCYSSKFLKH--WDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEK 153 Query: 133 AQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAE 192 AQ PE+ +G IPG GGTQRL R VG + A+EM+LT + A++ GL+ + P Sbjct: 154 AQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVET 213 Query: 193 LVTTARRWALDIVGRRKPWVS 213 LV A + A I K V+ Sbjct: 214 LVEEAIQCAEKIASNSKIVVA 234 >3MOY-A nrPDB Length = 263 Score = 209 bits (532), Expect = 3e-54, Method: Composition-based stats. Identities = 73/204 (35%), Positives = 110/204 (53%), Gaps = 6/204 (2%) Query: 16 DGVAVITLINP-PVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGFG 74 GV +I L P +N+L+ + + + + ++ AIV+TG++ F+ G DI+ Sbjct: 18 AGVGLIRLDRPDALNALNQTLEAEVLDAARDFDADLEIGAIVVTGSERAFAAGADIAEMV 77 Query: 75 EMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAAQ 134 + +E ++ D L RKP VAA+ G ALGGG ELAM C I+A A+ Sbjct: 78 TLTPHQARE-----RNLLSGWDSLTQVRKPIVAAVAGYALGGGCELAMLCDLVIAADTAR 132 Query: 135 LGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAELV 194 G PE+ LG++PG GGTQRL R VG KA+++ LT + + AEE +GL+ +VP A+L+ Sbjct: 133 FGQPEITLGILPGLGGTQRLTRAVGKAKAMDLCLTGRSLTAEEAERVGLVSRIVPAADLL 192 Query: 195 TTARRWALDIVGRRKPWVSSVSKT 218 A A I +P +V Sbjct: 193 DEALAVAQRIARMSRPAGRAVKDA 216 >6OJM-A nrPDB Length = 286 Score = 209 bits (532), Expect = 3e-54, Method: Composition-based stats. Identities = 53/219 (24%), Positives = 90/219 (41%), Gaps = 17/219 (7%) Query: 6 KGKTVMEVGG------DGVAVITLINPP-VNSLSFDVLYNLKSNYEEALSRNDVKAIVIT 58 + KT E +GVA I P N+ L + +A + ++++ Sbjct: 11 EWKTAKEYEDITYKKCNGVARIAFNRPEIRNAFRPKTTSELYDAFYDAYEDPSIGVVLLS 70 Query: 59 GAKG-------RFSGGFDISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDG 111 G F G D G +G V E ++I + L+ K +A + G Sbjct: 71 GEGPSPKDGGWAFCSGGDQKARG--HQGYVGEDGRHRLNILEVQRLIRFMPKVVIAVVPG 128 Query: 112 LALGGGLELAMACHARISA-PAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTS 170 A+GGG L + C +++ A + + G G+ L ++VG KA E+ Sbjct: 129 WAVGGGHSLHVVCDLTLASKEHAIFKQTDADVTSFDGGYGSAYLAKMVGQKKAREIFFLG 188 Query: 171 KPVKAEEGHSLGLIDAVVPPAELVTTARRWALDIVGRRK 209 + A+E +G+++ VVP AEL TA WA +I+ + Sbjct: 189 RNYSAQEAFEMGMVNKVVPHAELEDTAYEWAQEILAKSP 227 >3H81-A nrPDB Length = 278 Score = 209 bits (532), Expect = 4e-54, Method: Composition-based stats. Identities = 76/219 (34%), Positives = 114/219 (52%), Gaps = 12/219 (5%) Query: 1 MDSRTKGK------TVMEVGGDGVAVITLINPP-VNSLSFDVLYNLKSNYEEALSRNDVK 53 ++++T+G T++ V +ITL P +N+L+ V+ + S E D+ Sbjct: 12 LEAQTQGPGSMTYETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAATELDDDPDIG 71 Query: 54 AIVITGAKGRFSGGFDISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLA 113 AI+ITG+ F+ G DI ++ + L A R P++AA+ G A Sbjct: 72 AIIITGSAKAFAAGADIKEMADLTFADA-----FTADFFATWGKLAAVRTPTIAAVAGYA 126 Query: 114 LGGGLELAMACHARISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPV 173 LGGG ELAM C I+A A+ G PE++LGV+PG GG+QRL R +G KA+++ILT + + Sbjct: 127 LGGGCELAMMCDVLIAADTAKFGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTM 186 Query: 174 KAEEGHSLGLIDAVVPPAELVTTARRWALDIVGRRKPWV 212 A E GL+ VVP +L+T AR A I Sbjct: 187 DAAEAERSGLVSRVVPADDLLTEARATATTISQMSASAA 225 >2VSU-C nrPDB Length = 275 Score = 205 bits (522), Expect = 5e-53, Method: Composition-based stats. Identities = 54/207 (26%), Positives = 93/207 (44%), Gaps = 3/207 (1%) Query: 6 KGKTVMEVGGDGVAVITLINP-PVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRF 64 + KTV DG+A + L P N++S + + E +V+TGA + Sbjct: 7 RWKTVKVEIEDGIAFVILNRPEKRNAMSPTLNREMIDVLETLEQDPAAGVLVLTGAGEAW 66 Query: 65 SGGFDISG-FGEMQKGN-VKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAM 122 + G D+ F E+ G + + K + LL KP++A ++G GGG + Sbjct: 67 TAGMDLKEYFREVDAGPEILQEKIRREASQWQWKLLRMYAKPTIAMVNGWCFGGGFAPLV 126 Query: 123 ACHARISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLG 182 AC I A A GL E+ G+ PG ++ + VG ++L I+T K ++ +G Sbjct: 127 ACDLAICADEATFGLSEINWGIPPGNLVSKAMADTVGHRQSLYYIMTGKTFGGQKAAEMG 186 Query: 183 LIDAVVPPAELVTTARRWALDIVGRRK 209 L++ VP A+L A +++ + Sbjct: 187 LVNESVPLAQLREVTIELARNLLEKNP 213 >3OME-A nrPDB Length = 282 Score = 203 bits (515), Expect = 3e-52, Method: Composition-based stats. Identities = 59/227 (25%), Positives = 98/227 (43%), Gaps = 13/227 (5%) Query: 1 MDSRTKGKTVMEVGG----DGVAVITLINPPV-NSLSFDVLYNLKSNYEEALSRNDVKAI 55 ++++T+G M D +A ITL P N+ + ++L L + + A N+VK I Sbjct: 12 LEAQTQGPGSMVYIDYGVADSIATITLNRPEAANAQNPELLDELDAAWTRAAEDNEVKVI 71 Query: 56 VITGAKGRFSGGFDISGFGEMQKGNVKEPKAGYISIDIITDLL--EAARKPSVAAIDGLA 113 ++ FS G D+ G GE+ + E + + + L KPS+AA+ G Sbjct: 72 ILRANGKHFSAGHDLRGGGEVPEKISLEFIIQHEARRYLDYTLRWRNVPKPSIAAVQGRC 131 Query: 114 LGGGLELAMACHARISAPAAQLGLPELQLGV--IPGFGGTQRLPRLVGLTKALEMILTSK 171 + GGL L C +++ A P +G+ + G T L G KA E++ T + Sbjct: 132 ISGGLLLCWPCDLILASDDALFSDPVALMGIGGVEYHGHTWEL----GPRKAKEILFTGR 187 Query: 172 PVKAEEGHSLGLIDAVVPPAELVTTARRWALDIVGRRKPWVSSVSKT 218 + AEE G+++ VV EL R A I + + Sbjct: 188 ALTAEEAERTGMVNRVVARDELDAQTRELAEQIATMPPFALRQAKRA 234 >2PPY-A nrPDB Length = 265 Score = 200 bits (508), Expect = 2e-51, Method: Composition-based stats. Identities = 62/217 (28%), Positives = 105/217 (48%), Gaps = 5/217 (2%) Query: 4 RTKGKTVMEVGGDGVAVITLINPPVNSLSFDVLYNLKSNYEEALSRNDVKAI-VITGAKG 62 TK + + DG+A I L NS + + ++ D+K + V++ Sbjct: 5 ETKKQYLTVFKEDGIAEIHLHINKSNSYDLEFYKEFNAAIDDIRFDPDIKVVIVMSDVPK 64 Query: 63 RFSGGFDISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAM 122 FS G DI+ + + + D + + + +A ++G +GGGLE+A+ Sbjct: 65 FFSAGADINFLRSADP---RFKTQFCLFCNETLDKIARSPQVYIACLEGHTVGGGLEMAL 121 Query: 123 ACHARISAPAA-QLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSL 181 AC R A ++GLPE+ LGV+ G GGTQRL RL+G ++AL+M +T + + +E + Sbjct: 122 ACDLRFMGDEAGKIGLPEVSLGVLAGTGGTQRLARLIGYSRALDMNITGETITPQEALEI 181 Query: 182 GLIDAVVPPAELVTTARRWALDIVGRRKPWVSSVSKT 218 GL++ V P AE R +A + VS++ Sbjct: 182 GLVNRVFPQAETRERTREYARKLANSATYAVSNIKLA 218 >4FZW-A nrPDB Length = 258 Score = 194 bits (492), Expect = 1e-49, Method: Composition-based stats. Identities = 61/210 (29%), Positives = 101/210 (48%), Gaps = 6/210 (2%) Query: 10 VMEVGGDGVAVITLINPP-VNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGF 68 ++ V ++TL P N+L+ +L L + E A + + VITG F+ G Sbjct: 7 LIVSRQQRVLLLTLNRPAARNALNNALLMQLVNELEAAATDTSISVCVITGNARFFAAGA 66 Query: 69 DISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARI 128 D++ E + L+A KP +AA++G ALG G ELA+ C + Sbjct: 67 DLNEMAEKDLAATLNDTRP-----QLWARLQAFNKPLIAAVNGYALGAGCELALLCDVVV 121 Query: 129 SAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVV 188 + A+ GLPE+ LG++PG GGTQRL R VG + A +M+L+ + + A++ GL+ V Sbjct: 122 AGENARFGLPEITLGIMPGAGGTQRLIRSVGKSLASKMVLSGESITAQQAQQAGLVSDVF 181 Query: 189 PPAELVTTARRWALDIVGRRKPWVSSVSKT 218 P + A + A + + + + Sbjct: 182 PSDLTLEYALQLASKMARHSPLALQAAKQA 211 >5YLO-A nrPDB Length = 271 Score = 191 bits (484), Expect = 1e-48, Method: Composition-based stats. Identities = 51/193 (26%), Positives = 84/193 (43%), Gaps = 1/193 (0%) Query: 15 GDGVAVITLINPP-VNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGF 73 G+A + L P N+L L L + V+A+V+ G+ F G D++ + Sbjct: 12 EAGIAWLVLNRPQQRNALDIPTLEALHVRLDACERDPAVRAVVLGGSGRSFCAGADLAEW 71 Query: 74 GEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAA 133 + E + + L A KP+VAA++G A+G G++LA+ C RI+A +A Sbjct: 72 AAAEARGELESYGWTEAAHALMGRLHALDKPTVAAVNGSAVGAGMDLALCCDFRIAAASA 131 Query: 134 QLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAEL 193 + + P G + LPRL+G A ++ + AE GL+ VV L Sbjct: 132 RFKAGYTGMAYCPDAGASWHLPRLLGSEAAKRLLFLDEAWSAERALGAGLVGEVVADEHL 191 Query: 194 VTTARRWALDIVG 206 V +A + Sbjct: 192 VEAVGAFAARLAS 204 >1NZY-B nrPDB Length = 269 Score = 189 bits (479), Expect = 5e-48, Method: Composition-based stats. Identities = 58/241 (24%), Positives = 101/241 (41%), Gaps = 4/241 (1%) Query: 15 GDGVAVITLINP-PVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGF 73 DGVA IT+ P N+LS + + A + V A++ITGA+ F GF + Sbjct: 10 EDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLREI 69 Query: 74 GEMQ--KGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAP 131 + G + + + + ++P +AAI+G+A GGGL +++A I A Sbjct: 70 PLDKGVAGVRDHFRIAALWWHQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICAD 129 Query: 132 AAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPA 191 +A+ +G+ + L R+VG+ +A+E++LT + + EE GL+ V P Sbjct: 130 SAKFVCAWHTIGIGNDTATSYSLARIVGMRRAMELMLTDRTLYPEEAKDWGLVSRVYPKD 189 Query: 192 ELVTTARRWALDIVGRRKPWVSSVSKTDKLPPLGEAREILTFAKAQTLKRAPNMKHPLMC 251 E A + A ++ + + E F + H + C Sbjct: 190 EFREVAWKVARELAAAPTHLQVMAKERFHAGWMQPVEECTEFEIQNVIASV-THPHFMPC 248 Query: 252 L 252 L Sbjct: 249 L 249 >1EF9-A nrPDB Length = 261 Score = 189 bits (479), Expect = 5e-48, Method: Composition-based stats. Identities = 60/240 (25%), Positives = 109/240 (45%), Gaps = 12/240 (5%) Query: 8 KTVMEVGGDGVAVITLIN-PPVNSLSFDVLYNLKSNYEEALSRNDVKAIVITG--AKGRF 64 + V V + VAVI +N+LS + +L + +R +++ I++ F Sbjct: 4 QYVNVVTINKVAVIEFNYGRKLNALSKVFIDDLMQALSDL-NRPEIRCIILRAPSGSKVF 62 Query: 65 SGGFDISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMAC 124 S G DI ++P + + IT +++ KP ++ ++G GG E+ M+ Sbjct: 63 SAGHDIHEL----PSGGRDPLSYDDPLRQITRMIQKFPKPIISMVEGSVWGGAFEMIMSS 118 Query: 125 HARISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLI 184 I+A + + + LGV G L R G E+I T+ P+ A+ ++G++ Sbjct: 119 DLIIAASTSTFSMTPVNLGVPYNLVGIHNLTRDAGFHIVKELIFTASPITAQRALAVGIL 178 Query: 185 DAVVPPAELVTTARRWALDIVGRRKPWVSSVSKTDKLPPLGEAREILT--FAKAQTLKRA 242 + VV EL + A I + P +V K ++L LGEA + + F + Q ++RA Sbjct: 179 NHVVEVEELEDFTLQMAHHI-SEKAPLAIAVIK-EELRVLGEAHTMNSDEFERIQGMRRA 236 >4JWV-A nrPDB Length = 278 Score = 188 bits (478), Expect = 7e-48, Method: Composition-based stats. Identities = 64/202 (31%), Positives = 102/202 (50%), Gaps = 8/202 (3%) Query: 11 MEVGGDG-VAVITLINPP-VNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAK-GRFSGG 67 ++ +G VA + L P +N+++ ++ L + E + +D+ A+V++ F G Sbjct: 26 IDFRIEGHVAHVRLNRPQGLNAITQEMDDLLLDAWTEVNANSDIWAVVLSAEGEKAFCIG 85 Query: 68 FDISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHAR 127 D+SG E + I ++T +KP VAA+ G +GGG ELAM Sbjct: 86 ADVSGGAERKTRMALGGGLTGIGGPLVT-----CKKPMVAAVQGFCVGGGFELAMCADII 140 Query: 128 ISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAV 187 ++A AQ GLPE ++G+I G R R + AL++ILT + +KA+E GL++ V Sbjct: 141 VAADTAQFGLPETKVGIIGECGVVHRAMRQLPYHIALQLILTGERIKADEARHYGLVNEV 200 Query: 188 VPPAELVTTARRWALDIVGRRK 209 VP AEL A RWA + Sbjct: 201 VPFAELEEAALRWASKLNAASP 222 >4JCS-A nrPDB Length = 286 Score = 187 bits (475), Expect = 1e-47, Method: Composition-based stats. Identities = 63/258 (24%), Positives = 114/258 (44%), Gaps = 4/258 (1%) Query: 9 TVMEVGGDGVAVITLINP-PVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGG 67 T+ + V I + N ++ +L + E D++ +V+T G F G Sbjct: 25 TLDFEVVNNVGWIRMNRAAKHNPFDAELRADLMTVLERVRDDADIRVLVLTSHPGSFCAG 84 Query: 68 FDISGFGE-MQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHA 126 ++ + + G + + I D+L R P +AA+DG A G G L++ Sbjct: 85 GNLHVLRDNLDSGPAYWQQRIKTGLRFIHDMLNLGR-PVIAAVDGPAFGAGFALSLTADI 143 Query: 127 RISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDA 186 +++P A+ + L+LG++P G LPR VGL +A E++ +++ + AEE H LGL+ Sbjct: 144 VLASPRARFSMAYLRLGLVPDLGALYLLPRAVGLQRAKELMFSTRELDAEEAHRLGLVME 203 Query: 187 VVPPAELVTTARRWALDIVGRRKPWVSSVSKTDKLPPLGEAREILTFAKAQTLKRAPNMK 246 V L AR A +V + P +++K L + + +A + A + K Sbjct: 204 VHESEALEQRAREIAESLV-QAAPTALALTKAALNVSLDSDEQTMFSLEAASQAAAFSTK 262 Query: 247 HPLMCLDAIEVGIVSGPR 264 P ++A+ R Sbjct: 263 EPRAAIEALLSKQPPPFR 280 >5WYB-B nrPDB Length = 280 Score = 184 bits (466), Expect = 2e-46, Method: Composition-based stats. Identities = 71/221 (32%), Positives = 108/221 (48%), Gaps = 4/221 (1%) Query: 18 VAVITLINPPVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAK-GRFSGGFDISGFGEM 76 A+IT+ +PP N+ D L L+ E +D+ A+V+TG FS G D++ F + Sbjct: 27 TALITINHPPANTWDRDSLIGLRQLIEHLNRDDDIYALVVTGQGPKFFSAGADLNMFADG 86 Query: 77 QKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAAQLG 136 K +E + + L R S+AAI+G A+GGGLE A+AC RI+ AQ+ Sbjct: 87 DKARAREMARRF---GEAFEALRDFRGVSIAAINGYAMGGGLECALACDIRIAERQAQMA 143 Query: 137 LPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAELVTT 196 LPE +G++P GGTQ LP LVG A MIL ++ V AE +GL++ VV E Sbjct: 144 LPEAAVGLLPCAGGTQALPWLVGEGWAKRMILCNERVDAETALRIGLVEQVVDSGEARGA 203 Query: 197 ARRWALDIVGRRKPWVSSVSKTDKLPPLGEAREILTFAKAQ 237 A A + + + ++ + L + + Sbjct: 204 ALLLAAKVARQSPVAIRTIKPLIQGARERAPNTWLPEERER 244 >3T8B-A nrPDB Length = 334 Score = 183 bits (465), Expect = 2e-46, Method: Composition-based stats. Identities = 50/212 (23%), Positives = 81/212 (38%), Gaps = 17/212 (8%) Query: 15 GDGVAVITLINPPV-NSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKG-------RFSG 66 D + P V N+ + L + A DV +++TG F Sbjct: 64 DDATVRVAFNRPEVRNAFRPHTVDELYRVLDHARMSPDVGVVLLTGNGPSPKDGGWAFCS 123 Query: 67 GFDISGFGE--------MQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGL 118 G D G V +AG + I + L+ K + ++G A GGG Sbjct: 124 GGDQRIRGRSGYQYASGDTADTVDVARAGRLHILEVQRLIRFMPKVVICLVNGWAAGGGH 183 Query: 119 ELAMACHARISAPA-AQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEE 177 L + C +++ A+ + +G G G+ L R VG A E+ + AE+ Sbjct: 184 SLHVVCDLTLASREYARFKQTDADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTYTAEQ 243 Query: 178 GHSLGLIDAVVPPAELVTTARRWALDIVGRRK 209 H +G ++AV AEL T +WA +I + Sbjct: 244 MHQMGAVNAVAEHAELETVGLQWAAEINAKSP 275 >5VE2-A nrPDB Length = 275 Score = 179 bits (455), Expect = 3e-45, Method: Composition-based stats. Identities = 47/215 (21%), Positives = 95/215 (44%), Gaps = 7/215 (3%) Query: 4 RTKGKTVMEVGGDGVAVITLINPPV-NSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKG 62 ++ K++ + V +T+ P + N+L+ ++ L E + + ++A+++T Sbjct: 21 QSMSKSLNVSLNNRVLSLTINRPELKNALNRELYAALADELERSNHDDQIRAVLLTANGD 80 Query: 63 RFSGGFDISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAM 122 F+ G D+ F V+E +G S+ + P V A++G A+G GL + + Sbjct: 81 TFTAGNDLDDFI----NPVEE--SGTPSVIRFLKAISECETPIVVAVNGPAIGVGLTMLL 134 Query: 123 ACHARISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLG 182 C ++ +A+ P +G++P + LP VG A +++L + + A E S G Sbjct: 135 HCDMVYASKSARFRAPFTHVGLVPEAASSLLLPLAVGQAWANDLMLAGRILDAREALSAG 194 Query: 183 LIDAVVPPAELVTTARRWALDIVGRRKPWVSSVSK 217 L+ V LV + + A + V + Sbjct: 195 LVTRVFEDDVLVAESLKIAEQVASLAPNSVKQSKR 229 >4ZU2-A nrPDB Length = 272 Score = 179 bits (453), Expect = 4e-45, Method: Composition-based stats. Identities = 58/212 (27%), Positives = 97/212 (45%), Gaps = 2/212 (0%) Query: 8 KTVMEVGGDGVAVITLINPP-VNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSG 66 +T++ +GV ITL P N++S ++ L++ V+A+V+ GA G F Sbjct: 7 ETLLLEPIEGVLRITLNRPQSRNAMSLAMVGELRAVLAAVRDDRSVRALVLRGADGHFCA 66 Query: 67 GFDISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHA 126 G DI + + + + + + +AA + VA ++G LGGG LA Sbjct: 67 GGDIKDMAGARAAGAEAYRTLNRAFGSLLEEAQAAPQLLVALVEGAVLGGGFGLACVSDV 126 Query: 127 RISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDA 186 I+A AQ GLPE LG++P + R +GLT+A + LT+ E LGL+ Sbjct: 127 AIAAADAQFGLPETSLGILP-AQIAPFVVRRIGLTQARRLALTAARFDGREALRLGLVHF 185 Query: 187 VVPPAELVTTARRWALDIVGRRKPWVSSVSKT 218 A+ + L+ + R P ++ +K Sbjct: 186 CEADADALEQRLEETLEQLRRCAPNANAATKA 217 >5JBW-A nrPDB Length = 260 Score = 176 bits (447), Expect = 2e-44, Method: Composition-based stats. Identities = 75/211 (35%), Positives = 110/211 (52%), Gaps = 4/211 (1%) Query: 28 VNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKG-RFSGGFDISGFGEMQKGNVKEPKA 86 N++S +L L S DV+A+VITGA F G D+ M + V+ Sbjct: 25 RNAISRAMLKELGELVTRVSSSRDVRAVVITGAGDKAFCAGADLKERATMAEDEVRAFLD 84 Query: 87 GYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAAQLGLPELQLGVIP 146 G + +E + +AAI+G ALGGG ELA+AC R++APAA+LGL E++LG+IP Sbjct: 85 G---LRRTFRAIEKSDCVFIAAINGAALGGGTELALACDLRVAAPAAELGLTEVKLGIIP 141 Query: 147 GFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAELVTTARRWALDIVG 206 G GGTQRL RLVG +A ++ILT++ + A E S+GL + + P L+ A A +V Sbjct: 142 GGGGTQRLARLVGPGRAKDLILTARRINAAEAFSVGLANRLAPEGHLLAVAYGLAESVVE 201 Query: 207 RRKPWVSSVSKTDKLPPLGEAREILTFAKAQ 237 V++ E + L + Sbjct: 202 NAPIAVATAKHAIDEGTGLELDDALALELRK 232 >1XX4-A nrPDB Length = 261 Score = 171 bits (434), Expect = 8e-43, Method: Composition-based stats. Identities = 52/192 (27%), Positives = 88/192 (45%), Gaps = 6/192 (3%) Query: 10 VMEVGGDGVAVITLINPPVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGA-KGRFSGGF 68 V + G G+AV+ NPPVNSLS + L + E+ + ++ +++T G FS G Sbjct: 8 VEKEGEAGIAVMKFKNPPVNSLSLEFLTEFVISLEKLENDKSIRGVILTSERPGIFSAGL 67 Query: 69 DISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARI 128 D+ EM N + ++ + L + ++AI+G + GG +A+ C RI Sbjct: 68 DLM---EMYGRNPAHYAEYWKAVQELWLRLYLSNLTLISAINGASPAGGCLMALTCDYRI 124 Query: 129 SAPAAQ--LGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDA 186 A ++ +GL E LG++ F +G A + E +GL+D Sbjct: 125 MADNSKYTIGLNESLLGIVAPFWLKDNYVNTIGHRAAERALQLGTLFPPAEALKVGLVDE 184 Query: 187 VVPPAELVTTAR 198 VVP ++ + AR Sbjct: 185 VVPEDQVHSKAR 196 >4FZW-C nrPDB Length = 274 Score = 171 bits (433), Expect = 1e-42, Method: Composition-based stats. Identities = 58/227 (25%), Positives = 100/227 (44%), Gaps = 14/227 (6%) Query: 15 GDGVAVITLINPP-VNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGF 73 GV +TL P +NS + ++ L ++ + ++ +++TGA F G D++ Sbjct: 22 EKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLNDR 81 Query: 74 GEMQKGNVKEPKAGYISIDI-ITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPA 132 G + + L KP + A++G+A G G LA+ I+A + Sbjct: 82 NVDPTGPAPDLGMSVERFYNPLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARS 141 Query: 133 AQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAE 192 A+ + +LG+IP GGT LPR+ G +A+ + L + AE+ H G+I VV Sbjct: 142 AKFVMAFSKLGLIPDCGGTWLLPRVAGRARAMGLALLGNQLSAEQAHEWGMIWQVVDDET 201 Query: 193 LVTTARRWALDIVGRRKPWVSSVSKTDKLPPLGEAREILTFAKAQTL 239 L TA++ A + T LG ++ + A+ TL Sbjct: 202 LADTAQQLARHLA------------TQPTFGLGLIKQAINSAETNTL 236 >3I47-A nrPDB Length = 268 Score = 169 bits (429), Expect = 3e-42, Method: Composition-based stats. Identities = 47/206 (22%), Positives = 94/206 (45%), Gaps = 2/206 (0%) Query: 10 VMEVGGDGVAVITLIN-PPVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGF 68 ++ D V ++T+ N+ +L ++ + A++ +V+ IV+ FS G Sbjct: 6 LLYEIQDKVGLLTMNRISKHNAFDNQLLTEMRIRLDSAINDTNVRVIVLKANGKHFSAGA 65 Query: 69 DISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARI 128 D++ M +E + + + + + KP++A + G A GGG LA AC I Sbjct: 66 DLTWMQSMANFTEEENLEDSLVLGNLMYSISQSPKPTIAMVQGAAFGGGAGLAAACDIAI 125 Query: 129 SAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVV 188 ++ +A+ E++LG+IP + + R +G A + ++++ A +SL L+ V Sbjct: 126 ASTSARFCFSEVKLGLIPAV-ISPYVVRAIGERAAKMLFMSAEVFDATRAYSLNLVQHCV 184 Query: 189 PPAELVTTARRWALDIVGRRKPWVSS 214 P L+ ++A I V + Sbjct: 185 PDDTLLEFTLKYASQISNNAPEAVKN 210 >2A81-A nrPDB Length = 250 Score = 169 bits (428), Expect = 3e-42, Method: Composition-based stats. Identities = 56/224 (25%), Positives = 97/224 (43%), Gaps = 7/224 (3%) Query: 10 VMEVGGDGVAVITLINP-PVNSLSFDVLYNLKSNYEEALSRNDVKAIVITG-AKGRFSGG 67 V E D V VITL +P N S + ++K A + + V+A+V+ G A+ FS G Sbjct: 2 VFEENSDEVRVITLDHPNKHNPFSRTLETSVKDALARANADDSVRAVVVYGGAERSFSAG 61 Query: 68 FDISGFGEMQKGNVKEPKAGYIS-IDIITDLLEAARKPSVAAIDGLALGGGLELAMACHA 126 D F E+++ + E +I + + + KP++AA+DG A+G G + A+ Sbjct: 62 GD---FNEVKQLSRSEDIEEWIDRVIDLYQAVLNVNKPTIAAVDGYAIGMGFQFALMFDQ 118 Query: 127 RISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDA 186 R+ A A +PEL+ G+ G L G + E+I + + A L++ Sbjct: 119 RLMASTANFVMPELKHGIGCSVGAA-ILGFTHGFSTMQEIIYQCQSLDAPRCVDYRLVNQ 177 Query: 187 VVPPAELVTTARRWALDIVGRRKPWVSSVSKTDKLPPLGEAREI 230 VV + L+ A A + + + P + + Sbjct: 178 VVESSALLDAAITQAHVMASYPASAFINTKRAVNKPFIHLLEQT 221 >4JFC-A nrPDB Length = 281 Score = 169 bits (427), Expect = 6e-42, Method: Composition-based stats. Identities = 51/239 (21%), Positives = 100/239 (41%), Gaps = 13/239 (5%) Query: 4 RTKGKTVMEVGGDGVAVITLINPP-VNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKG 62 ++ + ++TL NP N+L ++ A + +++++VITG Sbjct: 21 QSMAGAIKSTSEGQTLILTLSNPEFRNALGPEIYAAGIEALNAAENNPEIRSVVITGEGA 80 Query: 63 RFSGGFDISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAM 122 F G ++ ++ + + D + KP +AA++G A G G LA+ Sbjct: 81 VFCAGGNLQRLQANRREAPEVQAQSIEGLHNWIDSIRTYPKPVIAAVEGAAAGAGFSLAL 140 Query: 123 ACHARISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLG 182 AC ++A A + +G+ P GG+ L R + A E+++ + + A+ H LG Sbjct: 141 ACDFVVAASNAVFVMSYSTVGLSPDGGGSWSLARSLPRALASELLMGGERISAQRLHDLG 200 Query: 183 LIDAVVPPAELVTTARRWALDIVGRRKPWVSSVSKTDKLPPLGEAREILTFAKAQTLKR 241 L++ V + ++ A R A + R L +E++ A + TL + Sbjct: 201 LVNKVASAGDALSEALRMAGQLNARAPNA------------LASIKELINEASSNTLSQ 247 >4IZC-A nrPDB Length = 275 Score = 168 bits (425), Expect = 8e-42, Method: Composition-based stats. Identities = 55/198 (27%), Positives = 90/198 (45%), Gaps = 4/198 (2%) Query: 11 MEVGGDGVAVITLINP-PVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFD 69 +++ +GV V+TL P N+L + L + + A R V+A+V+TGA F G D Sbjct: 14 LDLRDNGVCVVTLNRPDKRNALDVATIEELVTFFSTA-HRKGVRAVVLTGAGDHFCAGLD 72 Query: 70 ISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARIS 129 + + + + + + +E P +AA+ G +GGGL LA A H R+ Sbjct: 73 LVEHWKAD-RSADDFMHVCLRWHEAFNKMEYGGVPIIAALRGAVVGGGLALASAAHLRVM 131 Query: 130 APAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVP 189 + LPE Q G+ G G T R+ ++G + ++MILT + + +E LGL + Sbjct: 132 DQSTYFALPEGQRGIFTGGGATIRVSDMIGKYRMIDMILTGRVYQGQEAADLGLA-QYIT 190 Query: 190 PAELVTTARRWALDIVGR 207 A A I Sbjct: 191 EGSSFDKAMELADKIASN 208 >3HIN-A nrPDB Length = 275 Score = 166 bits (420), Expect = 3e-41, Method: Composition-based stats. Identities = 62/213 (29%), Positives = 97/213 (45%), Gaps = 8/213 (3%) Query: 18 VAVITLINPP-VNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGFGEM 76 V I L P N+L+ ++ LK + + ++A+VI G FS G D+S E Sbjct: 26 VLTIGLNRPKKRNALNDGLMAALKDCLTDIP--DQIRAVVIHGIGDHFSAGLDLSELRE- 82 Query: 77 QKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAAQLG 136 + E + + D ++ R P +AA+ G +GGGLELA A H R++ +A Sbjct: 83 --RDATEGLVHSQTWHRVFDKIQYCRVPVIAALKGAVIGGGLELACAAHIRVAEASAYYA 140 Query: 137 LPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAELVTT 196 LPE G+ G GG+ RLPRL+G+ + +M+LT + A EG G ++ Sbjct: 141 LPEGSRGIFVGGGGSVRLPRLIGVARMADMMLTGRVYSAAEGVVHGFSQYLIENGSAYDK 200 Query: 197 ARRWALDIVGRRKPWVSSVSKTDKLPPLGEARE 229 A + +V + LP + EA Sbjct: 201 ALELGNRVAQNAPLTNFAVLQA--LPMIAEANP 231 >3HE2-A nrPDB Length = 264 Score = 166 bits (420), Expect = 3e-41, Method: Composition-based stats. Identities = 57/221 (25%), Positives = 97/221 (43%), Gaps = 16/221 (7%) Query: 1 MDSRTKGKTVME--VGGDGVAVITLINPPV-NSLSFDVLYNLKSNYEEALSRNDVKAIVI 57 ++++T+G M + V I L P N+L+ ++ L +A +AIV+ Sbjct: 12 LEAQTQGPGSMIGITQAEAVLTIELQRPERRNALNSQLVEELTQAIRKA-GDGSARAIVL 70 Query: 58 TGAKGRFSGGFDISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGG 117 TG F G D+SG + + ++A+ P V AI+G A+G G Sbjct: 71 TGQGTAFCAGADLSG--------DAFAADYPDRLIELHKAMDASPMPVVGAINGPAIGAG 122 Query: 118 LELAMACHARISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEE 177 L+LAM C R+ AP A P + G+ +RL LVG +A M+L+++ + AE Sbjct: 123 LQLAMQCDLRVVAPDAFFQFPTSKYGLALDNWSIRRLSSLVGHGRARAMLLSAEKLTAEI 182 Query: 178 GHSLGLIDAVVPPAELVTTARRWALDIVGRRKPWVSSVSKT 218 G+ + + A+ A+ WA +I + + Sbjct: 183 ALHTGMANRIGTLAD----AQAWAAEIARLAPLAIQHAKRV 219 >3BPT-A nrPDB Length = 363 Score = 161 bits (406), Expect = 1e-39, Method: Composition-based stats. Identities = 47/178 (26%), Positives = 82/178 (46%), Gaps = 3/178 (1%) Query: 18 VAVITLINPP-VNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKG-RFSGGFDISGFGE 75 VITL P +N+L+ +++ + ++ + I+I GA G F G DI E Sbjct: 16 TGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVISE 75 Query: 76 MQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAAQL 135 +K K + ++ + + + +KP VA I G+ +GGG+ L++ R++ Sbjct: 76 AEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLF 135 Query: 136 GLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAEL 193 +PE +G+ P GG LPRL G + LT +K + + G+ V +L Sbjct: 136 AMPETAIGLFPDVGGGYFLPRLQG-KLGYFLALTGFRLKGRDVYRAGIATHFVDSEKL 192 >5KJP-A nrPDB Length = 265 Score = 160 bits (405), Expect = 2e-39, Method: Composition-based stats. Identities = 60/239 (25%), Positives = 103/239 (43%), Gaps = 10/239 (4%) Query: 2 DSRTKGKTVMEVGGDGVAVITLINPPV-NSLSFDVLYNLKSNYEEALSRNDVKAIVITGA 60 D+ V+ D + +IT+ P N+++ V L ++ + ++TG Sbjct: 9 DAANTEPEVLVEQRDRILIITINRPKAKNAVNAAVSRGLADAMDQLDGDAGLSVAILTGG 68 Query: 61 KGRFSGGFDISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLEL 120 G F G D+ F + V+ G+ KP +AA++G AL GG EL Sbjct: 69 GGSFCAGMDLKAFARGENVVVEGRGLGFTE--------RPPTKPLIAAVEGYALAGGTEL 120 Query: 121 AMACHARISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHS 180 A+A ++A + G+PE++ G++ G GG RLP + A+E+ LT + AE H Sbjct: 121 ALAADLIVAARDSAFGIPEVKRGLVAGGGGLLRLPERIPYAIAMELALTGDNLPAERAHE 180 Query: 181 LGLIDAVVPPAELVTTARRWALDIVGRRKPWVSSVSKTDKLPPLGEAREILTFAKAQTL 239 LGL++ + P + A A I P +K G + + + + + L Sbjct: 181 LGLVNVLAEPGTALDAAIALAEKITA-NGPLAVVATKRIITESRGWSPDTMFAEQMKIL 238 >4Q1J-A nrPDB Length = 268 Score = 159 bits (402), Expect = 5e-39, Method: Composition-based stats. Identities = 53/233 (22%), Positives = 94/233 (40%), Gaps = 10/233 (4%) Query: 24 INPPVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGFGEMQKGNVKE 83 N+ S ++ +L +E KA+++TG F+ G G +Q+G Sbjct: 41 DRTHKNAFSQELTDDLIQAFEYIRQNPKYKAVILTGYDNYFASGGTQEGLLRIQQG---- 96 Query: 84 PKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAAQLGLPELQLG 143 + D + L P +AA+ G +GGG + + I + + ++ G Sbjct: 97 --LTKFTDDNLYSLALDCEIPVIAAMQGHGIGGGFVMGLFADIVILSRESVYTANFMKYG 154 Query: 144 VIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAELVTTARRWALD 203 PG G T +P+ +G + A E++L + + + G+ V+P AE++ A A + Sbjct: 155 FTPGMGATFIVPKKLGFSLAQEILLNAGSYRGADLEKRGVPFKVLPRAEVLDYAVELAQE 214 Query: 204 IVGRRKPWVSSVSKTDKLPPLGEAREILTFAKAQTLKRAPNMKHPLMCLDAIE 256 + KP S V+ D L + R+ L Q L A H I+ Sbjct: 215 LA--EKPRNSLVTLKDHL--VAPLRDQLPRVIEQELMMAEKTFHHEEVKSRIK 263 >4HC8-A nrPDB Length = 255 Score = 154 bits (390), Expect = 1e-37, Method: Composition-based stats. Identities = 49/215 (22%), Positives = 86/215 (40%), Gaps = 4/215 (1%) Query: 14 GGDGVAVITLINPPVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGF 73 D +AVI++ + VN+L + L + + A DV A+VITG FSGGFD+ Sbjct: 11 RKDSIAVISMDDGKVNALGPAMQQALNAAIDNADRD-DVGALVITGNGRVFSGGFDLKIL 69 Query: 74 GEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAA 133 + + G + L + KP V A G A+ G L R++A A Sbjct: 70 TSGEVQPAIDMLRGGFE---LAYRLLSYPKPVVMACTGHAIAMGAFLLSCGDHRVAAHAY 126 Query: 134 QLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAEL 193 + E+ +G+ + + + + + + +K E + G ID + P + Sbjct: 127 NIQANEVAIGMTIPYAALEIMKLRLTRSAYQQATGLAKTFFGETALAAGFIDEIALPEVV 186 Query: 194 VTTARRWALDIVGRRKPWVSSVSKTDKLPPLGEAR 228 V+ A A + G + ++ + L R Sbjct: 187 VSRAEEAAREFAGLNQHAHAATKLRSRADALTAIR 221 >4JSB-A nrPDB Length = 296 Score = 154 bits (388), Expect = 2e-37, Method: Composition-based stats. Identities = 65/216 (30%), Positives = 99/216 (45%), Gaps = 23/216 (10%) Query: 3 SRTKGKTVMEVGGDG--------VAVITLINPPVNSLSFDVLYNLKSNYEEALSRNDVKA 54 ++TK T E+ G VA ITL P + ++ + L + V+ Sbjct: 23 AQTKAPTAEELAAAGLTLTIDGEVARITLSRPHRRNAMTGRMWTELARIGHTLPQA-VRI 81 Query: 55 IVITGAKGRFSGGFDISGFGEMQKGN--------VKEPKAGYISIDIITD------LLEA 100 +VITG FS G D+ F + ++P + +I L Sbjct: 82 VVITGEGPTFSSGIDLDMFQAGKVDGEPTPFTLLARDPNSTAALDQVIASYQEGFLWLRR 141 Query: 101 ARKPSVAAIDGLALGGGLELAMACHARISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGL 160 A S+AA+ G A+G G +LA++C RI + AQL + E LG++P GTQ L LVG+ Sbjct: 142 ADIVSIAAVRGHAIGAGFQLALSCDIRILSDTAQLCMKEPALGLVPDLTGTQPLVELVGV 201 Query: 161 TKALEMILTSKPVKAEEGHSLGLIDAVVPPAELVTT 196 +A+E+ LT++ + A E L L + VV AEL Sbjct: 202 NRAIELCLTARTIDAAEAAQLRLAERVVADAELDAA 237 >5MRE-88 nrPDB Length = 457 Score = 152 bits (384), Expect = 5e-37, Method: Composition-based stats. Identities = 46/205 (22%), Positives = 82/205 (40%), Gaps = 9/205 (4%) Query: 7 GKTVMEVGGDGVAVITLINPP-VNSLSFDVLYNLKSNYEEALSRNDVKAIVITGA--KGR 63 V+ D VITL P +N+L+ ++ ++ E + +++ + Sbjct: 1 APPVLFTVQDTARVITLNRPKKLNALNAEMSESMFKTLNEYAKSDTTNLVILKSSNRPRS 60 Query: 64 FSGGFDISGFGEM-QKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAM 122 F G D++ + + + + KP V +DG+ +GGG+ L++ Sbjct: 61 FCAGGDVATVAIFNFNKEFAKSIKFFTDEYSLNFQIATYLKPIVTFMDGITMGGGVGLSI 120 Query: 123 ACHARISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTK-----ALEMILTSKPVKAEE 177 RI+ + +PE+ +G P G T LPR+V L AL + LT + V + Sbjct: 121 HTPFRIATENTKWAMPEMDIGFFPDVGSTFALPRIVTLANSNSQMALYLCLTGEVVTGAD 180 Query: 178 GHSLGLIDAVVPPAELVTTARRWAL 202 + LGL V L +R Sbjct: 181 AYMLGLASHYVSSENLDALQKRLGE 205 >4HDT-A nrPDB Length = 353 Score = 148 bits (373), Expect = 9e-36, Method: Composition-based stats. Identities = 54/230 (23%), Positives = 98/230 (42%), Gaps = 6/230 (2%) Query: 6 KGKTVMEVGGDGVAVITLINPP-VNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGR- 63 K + V+ GV ++TL P +NSL+ ++ + + + V+A+++TGA R Sbjct: 7 KNEDVLVNVEGGVGLLTLNRPKAINSLTHGMVTTMAERLAAWENDDSVRAVLLTGAGERG 66 Query: 64 FSGGFDISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMA 123 G D+ K + E + + + + KP V+ +DG+ +GGG+ + Sbjct: 67 LCAGGDVVAIYHSAKADGAEARRFWFDEYRLNAHIGRYPKPYVSIMDGIVMGGGVGVGAH 126 Query: 124 CHARISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGL 183 + R+ ++ +PE+ +G IP GGT L R G L LT P + +G Sbjct: 127 GNVRVVTDTTKMAMPEVGIGFIPDVGGTYLLSRAPG-KLGLHAALTGAPFSGADAIVMGF 185 Query: 184 IDAVVPPAELVTTARRWALDIVGRRKPWVSSVSKTDKLPPLGEAREILTF 233 D VP ++ R I +++ ++ PL E R + Sbjct: 186 ADHYVPHDKIDEFTRAV---IADGVDAALAAHAQEPPASPLAEQRSWIDE 232 >4J2U-A nrPDB Length = 365 Score = 147 bits (370), Expect = 2e-35, Method: Composition-based stats. Identities = 59/283 (20%), Positives = 104/283 (36%), Gaps = 19/283 (6%) Query: 19 AVITLINPP-VNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAK-GRFSGGFDISGF-GE 75 ITL P +N+L+ ++ + + + +V+ +VI F G DI+ G Sbjct: 35 GRITLSRPAALNALTCAMVQEIDAALRGWIGDPEVELVVIDAEGPRAFCAGGDIAELHGR 94 Query: 76 MQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAAQL 135 G+ + + + D + A KP V+ + G +GGG+ L RI +Q+ Sbjct: 95 GVAGDHAFGQDFWRVEYRMNDRIAAFPKPIVSLMQGFTMGGGVGLGCHARHRIVGETSQI 154 Query: 136 GLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAELVT 195 +PE +G++P GGT L R G + + LT + + G D VP A+ Sbjct: 155 SMPECAIGLVPDVGGTHLLARAPG-RIGVWLGLTGARMGPGDAIFAGFADRFVPEADWPD 213 Query: 196 TARRWALDIVGRRKPWVSS-------------VSKTDKLPPLGEAREILTFAKAQTLKRA 242 AL+ P ++ L + E A +A Sbjct: 214 --LIAALEGGDLALPDHAAPEGRLPVLQDEIDRLFAGTLAEIPARLEATDTPLAAEALKA 271 Query: 243 PNMKHPLMCLDAIEVGIVSGPRAGLEKEAEVASQVVKLDTTKG 285 PL +E+ GP AG+ + ++ + + Sbjct: 272 LRRSSPLALAATLEILQRLGPSAGIREALDLEYRFTYRAQGQA 314 >3LAO-A nrPDB Length = 258 Score = 146 bits (369), Expect = 3e-35, Method: Composition-based stats. Identities = 46/198 (23%), Positives = 75/198 (37%), Gaps = 5/198 (2%) Query: 20 VITLIN-PPVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGFG-EMQ 77 +I L N+ +L +L E + + V+ F+ G D+ ++ Sbjct: 24 LIGLDRAGKRNAFDSAMLADLALAMGEYERSEESRCAVLFAHGEHFTAGLDLMELAPKLA 83 Query: 78 KGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAAQLGL 137 + P G ++ KP V A+ G G+EL + ++A + Sbjct: 84 ASGFRYPDGGVDPWGVVQPR---RSKPLVVAVQGTCWTAGIELMLNADIAVAARGTRFAH 140 Query: 138 PELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAELVTTA 197 E+ G+ P G T R PR G T A+ ILT A+E + L+ VV P E + A Sbjct: 141 LEVLRGIPPLGGSTVRFPRAAGWTDAMRYILTGDEFDADEALRMRLLTEVVEPGEELARA 200 Query: 198 RRWALDIVGRRKPWVSSV 215 +A I V + Sbjct: 201 LEYAERIARAAPLAVRAA 218 >3HP0-A nrPDB Length = 267 Score = 142 bits (358), Expect = 5e-34, Method: Composition-based stats. Identities = 44/186 (23%), Positives = 69/186 (37%), Gaps = 2/186 (1%) Query: 8 KTVMEVGGDGVAVITLINPPVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGG 67 +T+ V IT P N+ D L + V +V+ G F G Sbjct: 7 QTIKVRFQASVCYITFHRPEANNTINDTLIEECLQVLNQCETSTVTVVVLEGLPEVFCFG 66 Query: 68 FDISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHAR 127 D + K K+ + + + L+ +++ + G GGL A Sbjct: 67 ADFQEIYQEMKRGRKQASSQ-EPLYDLWMKLQTGPYVTISHVRGKVNAGGLGFVSATDIA 125 Query: 128 ISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAV 187 I+ A L EL G+ P L R +G KA M L +KP+ +E GLIDA Sbjct: 126 IADQTASFSLSELLFGLYPAC-VLPFLIRRIGRQKAHYMTLMTKPISVQEASEWGLIDAF 184 Query: 188 VPPAEL 193 +++ Sbjct: 185 DAESDV 190 >2NP9-A nrPDB Length = 440 Score = 125 bits (315), Expect = 5e-29, Method: Composition-based stats. Identities = 60/255 (23%), Positives = 98/255 (38%), Gaps = 28/255 (10%) Query: 13 VGGDGVAVITLINPP-VNSLSFDVLYNLKSNYEEALSRNDVKAIVITGA---------KG 62 DGVA +T+ +N+ + ++++ + AL V+ ++ G K Sbjct: 172 ERRDGVARLTMCRDDRLNAEDGQQVDDMETAVDLALLDPGVRVGLLRGGVMSHPRYRGKR 231 Query: 63 RFSGGFDISGFGEMQKGNVKEPKAGYISIDIITDLLE---------------AARKPSVA 107 FS G ++ Q G + I L+ KP VA Sbjct: 232 VFSAGINLKYLS--QGGISLVDFLMRRELGYIHKLVRGVLTNDDRPGWWHSPRIEKPWVA 289 Query: 108 AIDGLALGGGLELAMACHARISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMI 167 A+DG A+GGG +L + +++ A LP + G+IPG RL R G + ++I Sbjct: 290 AVDGFAIGGGAQLLLVFDRVLASSDAYFSLPAAKEGIIPGA-ANLRLGRFAGPRVSRQVI 348 Query: 168 LTSKPVKAEEGHSLGLIDAVVPPAELVTTARRWALDIVGRRKPWVSSVSKTDKLPPLGEA 227 L + + A+E + L+D VV P EL R + G + P G Sbjct: 349 LEGRRIWAKEPEARLLVDEVVEPDELDAAIERSLTRLDGDAVLANRRMLNLADESPDGFR 408 Query: 228 REILTFAKAQTLKRA 242 + FA Q L+ Sbjct: 409 AYMAEFALMQALRLY 423 >3M6N-A nrPDB Length = 305 Score = 122 bits (306), Expect = 5e-28, Method: Composition-based stats. Identities = 42/182 (23%), Positives = 80/182 (43%), Gaps = 7/182 (3%) Query: 55 IVITGAKGRFSGGFDISGFGEMQKGNVKEPKAGY-----ISIDIITDLLEAARKPSVAAI 109 +V+ F+ G D++ F ++ + + Y + L A R S+A + Sbjct: 89 VVLASDSDVFNLGGDLALFCQLIREGDRARLLDYAQRCVRGVHAFHVGLGA-RAHSIALV 147 Query: 110 DGLALGGGLELAMACHARISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILT 169 G ALGGG E A++CH I+ +GLPE+ + PG G + + + A +++L Sbjct: 148 QGNALGGGFEAALSCHTIIAEEGVMMGLPEVLFDLFPGMGAYSFMCQRISAHLAQKIMLE 207 Query: 170 SKPVKAEEGHSLGLIDAVVPPAELVTTARRWALDIVGRRKPWVSSVSKTDKLPPLGEARE 229 AE+ +GL+D VVP + V + + R +++ + ++ E Sbjct: 208 GNLYSAEQLLGMGLVDRVVPRGQGVAAVEQVIRE-SKRTPHAWAAMQQVREMTTAVPLEE 266 Query: 230 IL 231 ++ Sbjct: 267 MM 268 >3JU1-A nrPDB Length = 407 Score = 107 bits (267), Expect = 2e-23, Method: Composition-based stats. Identities = 40/181 (22%), Positives = 76/181 (41%), Gaps = 7/181 (3%) Query: 18 VAVITLI-NPPVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAK-GRFSGGFDISGFGE 75 V V+TL +N+L D++ + + +V+ G+ F G D+ Sbjct: 52 VGVVTLNVEKALNALDLDMVRAMTVQLNLWKKDPLIACVVLDGSGEKAFCAGGDVRALYH 111 Query: 76 M----QKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAP 131 + + K + + LL KP + DG+ +GGGL L ++ Sbjct: 112 ASVAAKGQVTEVAKVFFEEEYRLDYLLHTYGKPVLVWGDGIVMGGGLGLMAGASHKVVTE 171 Query: 132 AAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPA 191 +++ +PE+ +G+ P GG+ L R+ G L + LT+ + A + +GL D + Sbjct: 172 TSRIAMPEVTIGLYPDVGGSYFLNRMPG-KMGLFLGLTAYHMNAADACYVGLADHYLNRD 230 Query: 192 E 192 + Sbjct: 231 D 231 >4ZDC-A nrPDB Length = 300 Score = 77.0 bits (188), Expect = 3e-14, Method: Composition-based stats. Identities = 46/202 (22%), Positives = 71/202 (35%), Gaps = 12/202 (5%) Query: 20 VITLINPP-VNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGFGEMQK 78 +I LINP +N+L + L E A DV +I + FS G D G + Q Sbjct: 41 IIHLINPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSSGADFKGIAKAQG 100 Query: 79 GNVKEPKAGYISI--------DIITDLLEAARKPSVAAIDGLALGGGLELAMACHARIS- 129 + + + +TD K + ++G A+G L C S Sbjct: 101 DDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSAALVALCDIVYSI 160 Query: 130 APAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVV- 188 L P LG+I G T LP G E ++ +KP K + G I Sbjct: 161 NDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDIMCENGFISKNFN 220 Query: 189 -PPAELVTTARRWALDIVGRRK 209 P + + ++ + K Sbjct: 221 MPSSNAEAFNAKVLEELREKVK 242 >2BC1-A nrPDB Length = 490 Score = 47.8 bits (112), Expect = 2e-05, Method: Composition-based stats. Identities = 43/215 (20%), Positives = 70/215 (32%), Gaps = 20/215 (9%) Query: 197 ARRWALDIVGRRKPWVSSVSKTDKLPPLGEAR------EILTFAKAQTLKRAPNMKHPLM 250 A I G P S ++L LG + + + H Sbjct: 81 ALWIGEQIAG---PEGLFYSDKEELESLGAKVYMESPVQSIDYDAKTVTALVDGKNHVET 137 Query: 251 CLDAIEVGIVSGPRAGLEKEAEVASQVVKLDTTKGLIHVFFSQRGTAKVPGVTDRGLVPR 310 I ++ + T + L V Q + L + Sbjct: 138 YDKLIFATGSQPILPPIKGAEIKEGSLEFEATLENLQFVKLYQNSADVIAK-----LENK 192 Query: 311 KIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQ 370 IK+VA++G G +G +A A V+L +V + L R +L ++ + Q Sbjct: 193 DIKRVAVVGAGYIGVELAEAFQRKGKEVVLIDVVDTCLAGYYDRDLTDLMAKNMEEHGIQ 252 Query: 371 EKFEKTMSLLKGSLDYESF------RDVDMVIEAV 399 F +T+ + G+ E DVDMVI AV Sbjct: 253 LAFGETVKEVAGNGKVEKIITDKNEYDVDMVILAV 287 >6AON-A nrPDB Length = 478 Score = 44.7 bits (104), Expect = 2e-04, Method: Composition-based stats. Identities = 22/91 (24%), Positives = 40/91 (43%), Gaps = 4/91 (4%) Query: 277 VVKLDTTKGLIHVFFSQRGTAKVPGVTDRGLVPRKIKKVAIIGGGLMGSGIATALILSNY 336 V + + L + F ++ G + G VP KK+ +IG G++G + + Sbjct: 154 VATGSSARELPGLPFDEKNILSNDGALNIGAVP---KKLGVIGAGVIGLEMGSVWRRLGA 210 Query: 337 PVILKEVNEKFLEAGIGRVKAN-LQSRVRKG 366 V + E +FL A +V L+S ++G Sbjct: 211 EVTILEAMPEFLAAADQQVAKEALKSFAKQG 241 >2GF2-A nrPDB Length = 296 Score = 44.3 bits (103), Expect = 2e-04, Method: Composition-based stats. Identities = 20/113 (17%), Positives = 50/113 (44%), Gaps = 15/113 (13%) Query: 315 VAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEKFE 374 V IG G MG+ +A L+ YP+I+ +V + + V + EK + Sbjct: 3 VGFIGLGNMGNPMAKNLMKHGYPLIIYDVFPDAC----KEFQDAGEQVVSSPADVAEKAD 58 Query: 375 KTMSLLKGSLD-----------YESFRDVDMVIEAVIENISLKQQIFADLEKY 416 + +++L S++ + + ++I++ + ++ +++ ++EK Sbjct: 59 RIITMLPTSINAIEAYSGANGILKKVKKGSLLIDSSTIDPAVSKELAKEVEKM 111 >5ER0-A nrPDB Length = 518 Score = 43.2 bits (100), Expect = 4e-04, Method: Composition-based stats. Identities = 28/176 (15%), Positives = 62/176 (35%), Gaps = 18/176 (10%) Query: 294 RGTAKVPGVTDRGLVPRKIKKVAIIGGGLMGSGIATALILSNYPVILKE----VNEKFLE 349 + ++ K++ +IG G +G+ +A A + + V L + V K+ + Sbjct: 179 KLCKNWAHAQALIEDAKEAKRITVIGAGYIGAELAEAYSTTGHDVTLIDAMARVMPKYFD 238 Query: 350 AG-IGRVKANLQSRVRKGSMSQ--EKFEKTMSLLKGSLDYESFRDVDMVIEAVIENISLK 406 A ++ + + + ++ + E F + + L D S+ D+ I + + Sbjct: 239 ADFTDVIEQDYRDHGVQLALGETVESFTDSATGLTIKTDKNSYE-TDLAILCIGFRPNT- 296 Query: 407 QQIFADLEKYCPQHCILASNTSTIDLNKIGERTKSQDRIVGAHFFSPAH---IMPL 459 + P I+ + I S H+ +P H +PL Sbjct: 297 -DLLKGKVDMAPNGAIITDDYMRSSNPDIFAAGDS----AAVHY-NPTHQNAYIPL 346 >5U8W-A nrPDB Length = 481 Score = 41.6 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 36/241 (14%), Positives = 79/241 (32%), Gaps = 21/241 (8%) Query: 140 LQLGVIPGFGGTQRLPRLVGLTKA---LEMILTSKPVKAEEGHSLGLIDAVVPPAELVTT 196 + +G PG +GL A + K ++G +P L+ + Sbjct: 11 VVIGAGPGGYVAAIRAAQLGLKTACIEKYIGKEGKVALGGTCLNVG----CIPSKALLDS 66 Query: 197 ARRWALDIVGRRKPWVSSVSKTDKLPPLGEAREILTFAKAQTLK---RAPNMKH-----P 248 + ++ + + + T +P + + + + +A + Sbjct: 67 SYKYHEAKEAFKVHGIEAKGVTIDVPAMVARKANIVKNLTGGIATLFKANGVTSFEGHGK 126 Query: 249 LMCLDAIEVGIVSGPRAGLEKEAEVASQVVKLDTTKGLIHVFFSQRGTAKVPGVTDRGLV 308 L+ +EV + G LE E + + + + G + V Sbjct: 127 LLANKQVEVTGLDGKTQVLEAENVI---IASGSRPVEIPPAPLTDDIIVDSTGALEFQAV 183 Query: 309 PRKIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSM 368 P KK+ +IG G++G + + V + E +KFL A ++ + K + Sbjct: 184 P---KKLGVIGAGVIGLELGSVWARLGAEVTVLEALDKFLPAADEQIAKEALKVLTKQGL 240 Query: 369 S 369 + Sbjct: 241 N 241 >3CTV-A nrPDB Length = 110 Score = 41.2 bits (95), Expect = 0.002, Method: Composition-based stats. Identities = 22/82 (26%), Positives = 33/82 (40%), Gaps = 5/82 (6%) Query: 506 TQAAMFLVECG-ADPYLIDRAIS-KFGMPMGPFRLCDLVGFGVAIATATQFIENFSERTY 563 A+ LVE G A P ID AI P GPF L G + + F ++ + Sbjct: 28 INEAVKLVEMGVATPQDIDTAIKLGLNRPFGPFELAKQFGAEQIAKRLEELAKQFGKKIF 87 Query: 564 KSMIIP---LMQEDKRAGEATR 582 + ++E +AG+A Sbjct: 88 EPAKTLKEGKLEELLKAGKAEG 109 >4WJI-A nrPDB Length = 293 Score = 40.8 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 29/196 (14%), Positives = 63/196 (32%), Gaps = 47/196 (23%) Query: 309 PRKIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSM 368 ++ + +A+IG GL+GS IA +++ EK L I + + R G + Sbjct: 1 AQQFQTIALIGIGLIGSSIA------------RDIREKQLAGTIVVTTRSEATLKRAGEL 48 Query: 369 SQEKFEKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADLEKYCPQHCILAS--N 426 + E+ D+V+ +V + + A++ + I+ + Sbjct: 49 G-------LGDRYTLSAAEAVEGADLVVVSVP--VGASGAVAAEIAAHLKPGAIVTDVGS 99 Query: 427 TSTIDLNKIGERTKSQDRIVGAHFFSPAHIMPLLE------------------IVRTNHT 468 T + ++ + HF P H + E + T Sbjct: 100 TKGSVIAQMAPHL--PKDV---HFV-PGHPIAGTEHSGPDAGFAGLFRGRWCILTPPAGT 153 Query: 469 SAQVIVDLLDVGKKIK 484 + + L + + Sbjct: 154 DEEAVARLRLFWETLG 169 >4R16-A nrPDB Length = 418 Score = 40.5 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 17/89 (19%), Positives = 36/89 (40%), Gaps = 10/89 (11%) Query: 314 KVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEA---GIGRVKANLQSRVRKGSMSQ 370 ++A++G G +G A S Y V+ ++ + ++ G+ + R K +S Sbjct: 2 RIAVLGLGYIGLPTAIMFASSGYDVVGYDIRSEVIKKINSGVAHIIEPEIDRRLKEVLS- 60 Query: 371 EKFEKTMSLLKGSLDYESFRDVDMVIEAV 399 + LK + E + ++ I V Sbjct: 61 ------LGKLKVTDRVEDLKGSNVFIICV 83 >1NHQ-A nrPDB Length = 447 Score = 40.5 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 17/109 (15%), Positives = 41/109 (37%), Gaps = 6/109 (5%) Query: 297 AKVPGVTDRGLVPRKIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGI-GRV 355 + + V ++ V +IG G +G A A + V + ++ ++ L + Sbjct: 134 RQWAIKLKQKTVDPEVNNVVVIGSGYIGIEAAEAFAKAGKKVTVIDILDRPLGVYLDKEF 193 Query: 356 KANLQSRVRKGSMSQEKFEKTM-----SLLKGSLDYESFRDVDMVIEAV 399 L + +++ E ++ + ++ D D+V+ AV Sbjct: 194 TDVLTEEMEANNITIATGETVERYEGDGRVQKVVTDKNAYDADLVVVAV 242 >4D3F-A nrPDB Length = 310 Score = 40.5 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 21/109 (19%), Positives = 42/109 (38%), Gaps = 12/109 (11%) Query: 313 KKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEK 372 K V +IG G MG +A + Y V + + + + +R ++++ Sbjct: 22 KSVTVIGLGPMGQAMADVFLEYGYSVTVWNRTSSKADQLVA------KGAIRVSTVNEAL 75 Query: 373 FEKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADLEKYCPQHC 421 + +L + DY ++E V EN+ K + +L P+ Sbjct: 76 AANELVILSLT-DYNVMYS---ILEPVSENLFGK--VLVNLSSDTPEKA 118 >3OJO-A nrPDB Length = 431 Score = 40.5 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 17/100 (17%), Positives = 39/100 (39%), Gaps = 14/100 (14%) Query: 313 KKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEA-----------GIGRVKAN-LQ 360 K+ ++G G +G + V+ ++N++ ++ G+ V L Sbjct: 12 SKLTVVGLGYIGLPTSIMFAKHGVDVLGVDINQQTIDKLQNGQISIEEPGLQEVYEEVLS 71 Query: 361 SRVRKGSMSQEKFEKTMSLLKGSLDYESFRDVD--MVIEA 398 S K S + E + + + + + +R D +V+ A Sbjct: 72 SGKLKVSTTPEASDVFIIAVPTPNNDDQYRSCDISLVMRA 111 >4OQZ-A nrPDB Length = 289 Score = 39.3 bits (90), Expect = 0.006, Method: Composition-based stats. Identities = 20/87 (22%), Positives = 33/87 (37%), Gaps = 6/87 (6%) Query: 313 KKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEK 372 + V +IG G MG +A A + Y V L +A + R + + S ++ Sbjct: 3 QSVTVIGLGPMGQAMAAAYLDRGYEVTLWNRTASRADALVARGAKLAATPEQALSANELV 62 Query: 373 FEKTMSLLKGSLDYESFRDVDMVIEAV 399 +SL+ Y + EAV Sbjct: 63 ---ILSLIDYDAMYGVLEGAE---EAV 83 >3BF0-A nrPDB Length = 593 Score = 38.9 bits (89), Expect = 0.007, Method: Composition-based stats. Identities = 38/265 (14%), Positives = 71/265 (26%), Gaps = 70/265 (26%) Query: 40 KSNYEEALSRNDVKAIVITGAKGRFSGGFDISGFGEMQKGNVKEPKAGYISIDIITDLLE 99 + +A VKAIV+ G ++ ++ AG Sbjct: 328 AAQIRDARLDPKVKAIVLRVNSP----GGSVTASEVIRAELAAARAAG------------ 371 Query: 100 AARKPSVAAIDGLALGGGLELAMACHARISAPAA------QLGLPEL------QLGVIPG 147 KP V ++ G+A GG ++ + ++ P+ G+ +GV Sbjct: 372 ---KPVVVSMGGMAASGGYWISTPANYIVANPSTLTGSIGIFGVITTVENSLDSIGVHTD 428 Query: 148 FGGTQRLP-----RLVGLTKALEMILT----------------------------SKPVK 174 T L R + L M L+ Sbjct: 429 GVSTSPLADVSITRALPPEAQLMMQLSIENGYKRFITLVADARHSTPEQIDKIAQGHVWT 488 Query: 175 AEEGHSLGLIDAVVPPAELVTTARRWALDIVGRRKPWVSSVSKTDKLPPLGEAREILTFA 234 ++ + GL+D++ + V A A + K W + + Sbjct: 489 GQDAKANGLVDSLGDFDDAVAKAAELA-----KVKQWHLEYYVDEPTFFDKVMDNMSGSV 543 Query: 235 KAQTLKRAPNM-KHPLMCLDAIEVG 258 +A M PL + + Sbjct: 544 RAMLPDAFQAMLPAPLASVASTVKS 568 >4XRR-A nrPDB Length = 456 Score = 38.5 bits (88), Expect = 0.009, Method: Composition-based stats. Identities = 18/86 (20%), Positives = 30/86 (34%), Gaps = 4/86 (4%) Query: 314 KVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEKF 373 KV I G G +G+ +A L V+ + + + ++A G + Sbjct: 17 KVVIAGAGYVGTCLAVTLAGRGAEVVAVDSDP----GTVADLRAGRCRLPEPGLAGAVRD 72 Query: 374 EKTMSLLKGSLDYESFRDVDMVIEAV 399 L S Y+ D+VI V Sbjct: 73 LAATGRLTASTSYDPVGAADVVIVTV 98 >3KVE-A nrPDB Length = 486 Score = 38.1 bits (87), Expect = 0.012, Method: Composition-based stats. Identities = 10/35 (28%), Positives = 18/35 (51%) Query: 313 KKVAIIGGGLMGSGIATALILSNYPVILKEVNEKF 347 K V ++G G+ G A L + + V + E +E+ Sbjct: 34 KHVVVVGAGMSGLSAAYVLAGAGHKVTVLEASERA 68 >4ND4-A nrPDB Length = 321 Score = 38.1 bits (87), Expect = 0.012, Method: Composition-based stats. Identities = 18/85 (21%), Positives = 33/85 (38%), Gaps = 13/85 (15%) Query: 313 KKVAIIGGGLMGSGIATALILSNYP-VILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQE 371 +K+A+IG G +G IA + N V+L ++ E + + ++ + Sbjct: 5 RKIAVIGSGQIGGNIAYIVGKDNLADVVLFDIAEGIPQGKALDITHSMVMFGSTSKV--- 61 Query: 372 KFEKTMSLLKGSLDYESFRDVDMVI 396 G+ DY D+VI Sbjct: 62 ---------IGTNDYADISGSDVVI 77 >1F8S-A nrPDB Length = 498 Score = 38.1 bits (87), Expect = 0.015, Method: Composition-based stats. Identities = 11/34 (32%), Positives = 18/34 (52%) Query: 313 KKVAIIGGGLMGSGIATALILSNYPVILKEVNEK 346 K V I+G G+ G A L + + V + E +E+ Sbjct: 34 KHVVIVGAGMAGLSAAYVLAGAGHQVTVLEASER 67 >1PS9-A nrPDB Length = 671 Score = 37.8 bits (86), Expect = 0.019, Method: Composition-based stats. Identities = 21/138 (15%), Positives = 41/138 (29%), Gaps = 9/138 (6%) Query: 227 AREILTFAKAQTLKRAPNMKHPLMCLDAIEVGIVSGPRAGLEKEAEVASQVVKLDTTKGL 286 A +IL+ A + A L + G + Q+ T L Sbjct: 295 ADDILSRGDADMVSMARPFLADAELLSKAQSGRADEINTCIGCNQACLDQIFVGKVTSCL 354 Query: 287 IHVFFSQRGTAKVPGVTDRGLVPRKIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEK 346 + + R + L + K +A++G G G A + V L + + + Sbjct: 355 V----NPRACHE---TKMPILPAVQKKNLAVVGAGPAGLAFAINAAARGHQVTLFDAHSE 407 Query: 347 FLEAGIGRVKANLQSRVR 364 G + + + Sbjct: 408 I--GGQFNIAKQIPGKEE 423 >1LTH-T nrPDB Length = 319 Score = 37.4 bits (85), Expect = 0.023, Method: Composition-based stats. Identities = 23/86 (26%), Positives = 36/86 (41%), Gaps = 15/86 (17%) Query: 313 KKVAIIGGGLMGSGIATALILSNY--PVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQ 370 K+A+IG G +GS +A A ++L+++ RV+A + S Sbjct: 8 TKLAVIGAGAVGSTLAFAAAQRGIAREIVLEDI-------AKERVEAEVLDMQHGSSFYP 60 Query: 371 EKFEKTMSLLKGSLDYESFRDVDMVI 396 + GS D E RD DMV+ Sbjct: 61 TVS------IDGSDDPEICRDADMVV 80 >5X6R-A nrPDB Length = 420 Score = 37.4 bits (85), Expect = 0.024, Method: Composition-based stats. Identities = 15/62 (24%), Positives = 25/62 (40%), Gaps = 1/62 (1%) Query: 313 KKVAIIGGGLMGSGIATALILSNYPVILKEVNEK-FLEAGIGRVKANLQSRVRKGSMSQE 371 + VAIIG GL+G A A Y V L + + L+ + ++ + + Sbjct: 29 ESVAIIGAGLVGCLAALAFSKEGYNVTLYDFRQDPRLDTTKNKNLKSINLAISARGIDAL 88 Query: 372 KF 373 K Sbjct: 89 KS 90 >2UYY-A nrPDB Length = 316 Score = 37.4 bits (85), Expect = 0.026, Method: Composition-based stats. Identities = 26/110 (23%), Positives = 42/110 (38%), Gaps = 18/110 (16%) Query: 306 GLVPRKIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLE------AGIGRVKANL 359 G + KK+ +G GLMGSGI + L+ + V + + + A +GR A + Sbjct: 24 GSITPTDKKIGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKCDLFIQEGARLGRTPAEV 83 Query: 360 QSR--VRKGSMSQEKFEK--------TMSLLKGSLDYESFR--DVDMVIE 397 S + +S K K + ++ Y D D V E Sbjct: 84 VSTCDITFACVSDPKAAKDLVLGPSGVLQGIRPGKCYVDMSTVDADTVTE 133 >4PLF-A nrPDB Length = 334 Score = 37.0 bits (84), Expect = 0.027, Method: Composition-based stats. Identities = 18/85 (21%), Positives = 31/85 (36%), Gaps = 13/85 (15%) Query: 313 KKVAIIGGGLMGSGIATALILSNY-PVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQE 371 KK+++IG G++G +A V+L +V N+ Sbjct: 9 KKISLIGSGMIGGTMAYLCAQKELGDVVLFDV------------VKNMPQGKALDLSHSS 56 Query: 372 KFEKTMSLLKGSLDYESFRDVDMVI 396 T + G+ YE + D+VI Sbjct: 57 SIADTNVKVTGTNSYEDIKGSDVVI 81 >3GGO-A nrPDB Length = 314 Score = 37.0 bits (84), Expect = 0.028, Method: Composition-based stats. Identities = 23/118 (19%), Positives = 43/118 (36%), Gaps = 14/118 (11%) Query: 312 IKKVAIIGGGLMGSGIATALILSNY--PVILKEVNEKFLEAG--IGRVKANLQSRVRKGS 367 ++ V I+G G MG A +L S + + ++N + + +G + S + Sbjct: 33 MQNVLIVGVGFMGGSFAKSLRRSGFKGKIYGYDINPESISKAVDLGIIDEGTTSIAKVED 92 Query: 368 MSQ-----EKFEKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADLEKYCPQH 420 S +T + L Y D V + S+K ++ DLE + Sbjct: 93 FSPDFVMLSSPVRTFREIAKKLSYILSEDA-----TVTDQGSVKGKLVYDLENILGKR 145 >2G5C-A nrPDB Length = 281 Score = 37.0 bits (84), Expect = 0.028, Method: Composition-based stats. Identities = 23/118 (19%), Positives = 43/118 (36%), Gaps = 14/118 (11%) Query: 312 IKKVAIIGGGLMGSGIATALILSNY--PVILKEVNEKFLEAG--IGRVKANLQSRVRKGS 367 ++ V I+G G MG A +L S + + ++N + + +G + S + Sbjct: 1 MQNVLIVGVGFMGGSFAKSLRRSGFKGKIYGYDINPESISKAVDLGIIDEGTTSIAKVED 60 Query: 368 MSQ-----EKFEKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADLEKYCPQH 420 S +T + L Y D V + S+K ++ DLE + Sbjct: 61 FSPDFVMLSSPVRTFREIAKKLSYILSEDA-----TVTDQGSVKGKLVYDLENILGKR 113 >1REO-A nrPDB Length = 486 Score = 37.0 bits (84), Expect = 0.028, Method: Composition-based stats. Identities = 10/35 (28%), Positives = 18/35 (51%) Query: 313 KKVAIIGGGLMGSGIATALILSNYPVILKEVNEKF 347 K V ++G G+ G A L + + V + E +E+ Sbjct: 34 KHVVVVGAGMSGLSAAYVLSGAGHQVTVLEASERA 68 >1MV8-A nrPDB Length = 436 Score = 37.0 bits (84), Expect = 0.031, Method: Composition-based stats. Identities = 15/80 (18%), Positives = 35/80 (43%), Gaps = 12/80 (15%) Query: 314 KVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLE---AGIGRVKA-NLQSRVRKGSMS 369 +++I G G +G+ A L + VI +V+ ++ G + L++ +++G + Sbjct: 2 RISIFGLGYVGAVCAGCLSARGHEVIGVDVSSTKIDLINQGKSPIVEPGLEALLQQGRQT 61 Query: 370 QEKFEKTMSLLKGSLDYESF 389 L G+ D++ Sbjct: 62 --------GRLSGTTDFKKA 73 >4J90-A nrPDB Length = 222 Score = 36.6 bits (83), Expect = 0.035, Method: Composition-based stats. Identities = 12/38 (31%), Positives = 20/38 (52%) Query: 313 KKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEA 350 K+ A+IG G G I L + V+ ++NE+ + A Sbjct: 7 KQFAVIGLGRFGGSICKELHRMGHEVLAVDINEEKVNA 44 >2HMT-A nrPDB Length = 144 Score = 36.6 bits (83), Expect = 0.036, Method: Composition-based stats. Identities = 12/38 (31%), Positives = 20/38 (52%) Query: 313 KKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEA 350 K+ A+IG G G I L + V+ ++NE+ + A Sbjct: 7 KQFAVIGLGRFGGSIVKELHRMGHEVLAVDINEEKVNA 44 >5BUT-A nrPDB Length = 288 Score = 36.6 bits (83), Expect = 0.040, Method: Composition-based stats. Identities = 12/38 (31%), Positives = 20/38 (52%) Query: 313 KKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEA 350 K+ A+IG G G I L + V+ ++NE+ + A Sbjct: 7 KQFAVIGLGRFGGSIVKELHRMGHEVLAVDINEEKVNA 44 Score = 36.6 bits (83), Expect = 0.040, Method: Composition-based stats. Identities = 12/38 (31%), Positives = 20/38 (52%) Query: 313 KKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEA 350 K+ A+IG G G I L + V+ ++NE+ + A Sbjct: 149 KQFAVIGLGRFGGSIVKELHRMGHEVLAVDINEEKVNA 186 >1A5Z-A nrPDB Length = 319 Score = 36.6 bits (83), Expect = 0.040, Method: Composition-based stats. Identities = 28/144 (19%), Positives = 58/144 (40%), Gaps = 25/144 (17%) Query: 314 KVAIIGGGLMGSGIATALILSNY--PVILKEVNEKFLEA-GIGRVKANLQSRVRKGSMSQ 370 K+ I+G G +GS A AL++ + ++L +V++K E + + R+ ++ Sbjct: 2 KIGIVGLGRVGSSTAFALLMKGFAREMVLIDVDKKRAEGDALDLIHGT--PFTRRANI-- 57 Query: 371 EKFEKTMSLLKGSLDYESFRDVDMVIEA--VIENI-SLKQQIFADLEKYCPQHCILASNT 427 + DY + D+VI A V + + Q+ + + +A N Sbjct: 58 -----------YAGDYADLKGSDVVIVAAGVPQKPGETRLQLLGRNARVMKE---IARNV 103 Query: 428 STIDLNKIGERTKSQDRIVGAHFF 451 S + I + ++ +FF Sbjct: 104 SKYAPDSIVIVVTNPVDVL-TYFF 126 >3G0O-A nrPDB Length = 303 Score = 36.6 bits (83), Expect = 0.043, Method: Composition-based stats. Identities = 20/131 (15%), Positives = 47/131 (35%), Gaps = 26/131 (19%) Query: 314 KVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEKF 373 V I+G G MG G A + + + ++N + + + +G+ Sbjct: 9 HVGIVGLGSMGMGAARSCLRAGLSTWGADLNPQACA-----------NLLAEGACGAAAS 57 Query: 374 EKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFAD--LEKYCPQH-CILASNT-ST 429 + + + VD ++ V+ ++Q +F + + ++ S+T S+ Sbjct: 58 AREFAGV-----------VDALVILVVNAAQVRQVLFGEDGVAHLMKPGSAVMVSSTISS 106 Query: 430 IDLNKIGERTK 440 D +I Sbjct: 107 ADAQEIAAALT 117 >4HTF-A nrPDB Length = 285 Score = 36.2 bits (82), Expect = 0.045, Method: Composition-based stats. Identities = 22/163 (13%), Positives = 54/163 (33%), Gaps = 21/163 (12%) Query: 264 RAGLEKEAEVASQVVKLDTTKGLIHVFFSQRGTAKVPGVTDRGLVPRKIKKVAIIGGGLM 323 + AE S+ + T L Q DR L +K+ ++ G Sbjct: 27 DRNFDDIAEKFSRNIYGTTKGQLRQAILWQDL--------DRVLAEMGPQKLRVLDAGGG 78 Query: 324 GSGIATALILSNYPVILKEVNEKFLEAGIGRVK-ANLQSRVRKGSMSQEKFEKTMSLLKG 382 A + + VIL +++ + ++ + + ++ + + + Sbjct: 79 EGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETP-- 136 Query: 383 SLDYESFRDVDMVI-EAVIENISLKQQIFADLEKYCPQHCILA 424 VD+++ AV+E ++ + + L +L+ Sbjct: 137 ---------VDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLS 170 >2EQ6-A nrPDB Length = 464 Score = 36.2 bits (82), Expect = 0.045, Method: Composition-based stats. Identities = 39/234 (16%), Positives = 67/234 (28%), Gaps = 30/234 (12%) Query: 159 GLTKALEMILTSKPVKAEEGHSLG---LIDAVVPPAELVTTA-----RRWALDIVGRRKP 210 G A+ V A E +G L +P L+ A + A + KP Sbjct: 18 GYHAAIRAAQLGLKVLAVEAGEVGGVCLNVGCIPTKALLHAAETLHHLKVAEGFGLKAKP 77 Query: 211 WVSSVS----KTDKLPPL-GEAREILTFAKAQTLKRAPNMKHPLMCLDAIEVGIVSGPRA 265 + + + L G +L + L+ + P Sbjct: 78 ELDLKKLGGWRDQVVKKLTGGVGTLLKGNGVELLRGFARLVGPKEV------------EV 125 Query: 266 GLEKEAEVASQVVKLDTTKGLIHVFFS-QRGTAKVPGVTDRGLVPRKIKKVAIIGGGLMG 324 G E+ + + L F + + GL K++ +IGGG +G Sbjct: 126 GGERYGAKSLILATGSEPLELKGFPFGEDVWDSTRALKVEEGLP----KRLLVIGGGAVG 181 Query: 325 SGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEKFEKTMS 378 + V L E + L G A L+ + K + K + Sbjct: 182 LELGQVYRRLGAEVTLIEYMPEILPQGDPETAALLRRALEKEGIRVRTKTKAVG 235 >1VPD-A nrPDB Length = 299 Score = 36.2 bits (82), Expect = 0.047, Method: Composition-based stats. Identities = 13/77 (16%), Positives = 37/77 (48%), Gaps = 4/77 (5%) Query: 314 KVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEKF 373 KV IG G+MG ++ L+ + Y +++ + N + + + A ++ +++++ Sbjct: 7 KVGFIGLGIMGKPMSKNLLKAGYSLVVSDRNPEAIA---DVIAAGAETASTAKAIAEQ-C 62 Query: 374 EKTMSLLKGSLDYESFR 390 + +++L S + Sbjct: 63 DVIITMLPNSPHVKEVA 79 >2VHY-A nrPDB Length = 377 Score = 36.2 bits (82), Expect = 0.053, Method: Composition-based stats. Identities = 45/275 (16%), Positives = 80/275 (29%), Gaps = 60/275 (21%) Query: 138 PELQLGVIPGFGGTQRLPRL-----VGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAE 192 E ++ + P G L R + +T KA +G D V A+ Sbjct: 12 NEFRVAITP--AGVAELTRRGHEVLIQAGAGEGSAITDADFKAAGAQLVGTADQVWADAD 69 Query: 193 LVTTARR-WALDIVGRR------KPWVSSVSKTDKLPPLGEAREILTFAKAQTLKRAPNM 245 L+ + A + R + S+ L + + QT A + Sbjct: 70 LLLKVKEPIAAEYGRLRHGQILFTFLHLAASRACTDALLDSGTTSIAYETVQTADGALPL 129 Query: 246 KHPLMCLDAIEVGIVSGPRAGLEKEAEVASQVVKLDTTKGLIHVFFSQRGTAKVPGVTDR 305 P+ +EVA ++ + + R T GV Sbjct: 130 LAPM---------------------SEVAGRLA------AQVGAYHLMR-TQGGRGVLMG 161 Query: 306 GLVPRKIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRK 365 G+ + V +IG G G A V + ++N L Sbjct: 162 GVPGVEPADVVVIGAGTAGYNAARIANGMGATVTVLDINIDKLRQ--------------- 206 Query: 366 GSMSQEKFEKTMSLLKGSLDYE-SFRDVDMVIEAV 399 + E + + + + E + + D+VI AV Sbjct: 207 --LDAEFCGRIHTRYSSAYELEGAVKRADLVIGAV 239 >5Y77-A nrPDB Length = 473 Score = 36.2 bits (82), Expect = 0.053, Method: Composition-based stats. Identities = 13/41 (31%), Positives = 19/41 (46%) Query: 306 GLVPRKIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEK 346 G ++V IIG GL G+ +A L + + V L E Sbjct: 2 GTATDNARQVTIIGAGLAGTLVARLLARNGWQVNLFERRPD 42 >4OQY-A nrPDB Length = 290 Score = 36.2 bits (82), Expect = 0.057, Method: Composition-based stats. Identities = 22/110 (20%), Positives = 40/110 (36%), Gaps = 14/110 (12%) Query: 313 KKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEK 372 + V +IG G MG + + + + V + EA V +G++ Sbjct: 4 QSVTVIGLGPMGQAMVNTFLDNGHEVTVWNRTASKAEA-----------LVARGAVLAPT 52 Query: 373 FEKTMS-LLKGSLDYESFRDVDMVIEAVIENISLKQQIFADLEKYCPQHC 421 E +S L + V ++E V ++S K + A+L P Sbjct: 53 VEDALSANELIVLSLTDYDAVYAILEPVTGSLSGK--VIANLSSDTPDKA 100 >5JE8-A nrPDB Length = 302 Score = 35.8 bits (81), Expect = 0.059, Method: Composition-based stats. Identities = 13/42 (30%), Positives = 22/42 (52%) Query: 306 GLVPRKIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKF 347 G +KK+ IG G MG ++ L+ S Y V ++N++ Sbjct: 1 GSAKDPMKKIGFIGLGNMGLPMSKNLVKSGYTVYGVDLNKEA 42 >6C6P-A nrPDB Length = 458 Score = 35.8 bits (81), Expect = 0.068, Method: Composition-based stats. Identities = 13/50 (26%), Positives = 23/50 (46%) Query: 306 GLVPRKIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRV 355 G + +V I+G G++GS +A L V + E + K + +G Sbjct: 1 GTSSQNDPEVIIVGAGVLGSALAAVLSRDGRKVTVIERDLKEPDRIVGEF 50 >3PQF-A nrPDB Length = 326 Score = 35.8 bits (81), Expect = 0.069, Method: Composition-based stats. Identities = 32/156 (20%), Positives = 62/156 (39%), Gaps = 31/156 (19%) Query: 310 RKIKKVAIIGGGLMGSGIATALILSNY--PVILKEVNEKFLEAGIGRVKANLQSRVRKGS 367 + + KVA+IG G +GS A ALI +++ +VN++ +G V Sbjct: 3 KHVNKVALIGAGFVGSSYAFALINQGITDELVVIDVNKE---KAMGDVM----------D 49 Query: 368 MSQEKFEKTMSLLKGSLDYESFRDVDMV--------------IEAVIENISLKQQIFADL 413 ++ K + YE +D D+V +E V +N+ + + I +++ Sbjct: 50 LNHGKAFAPQPVKTSYGTYEDCKDADIVCICAGANQKPGETRLELVEKNLKIFKGIVSEV 109 Query: 414 EKYCPQHCIL-ASNTSTIDLNKIGERTKSQ-DRIVG 447 L A+N I + + +R++G Sbjct: 110 MASGFDGIFLVATNPVDILTYATWKFSGLPKERVIG 145 >5DT9-A nrPDB Length = 387 Score = 35.4 bits (80), Expect = 0.087, Method: Composition-based stats. Identities = 15/56 (26%), Positives = 27/56 (48%), Gaps = 2/56 (3%) Query: 313 KKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSM 368 K V IIG G +GS +A L V+L + ++ G R L++ +++ + Sbjct: 124 KTVGIIGAGQVGSYLAKCLSGIGMKVLLNDPPKQA--QGDEREFTELETLLKQADV 177 >3VTF-A nrPDB Length = 444 Score = 35.4 bits (80), Expect = 0.092, Method: Composition-based stats. Identities = 14/47 (29%), Positives = 24/47 (51%), Gaps = 2/47 (4%) Query: 306 GLVPR--KIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEA 350 GLVPR + ++++G G +G A L + V+ +VN +E Sbjct: 13 GLVPRGSHMASLSVLGLGYVGVVHAVGFALLGHRVVGYDVNPSIVER 59 >3DOJ-A nrPDB Length = 310 Score = 35.1 bits (79), Expect = 0.11, Method: Composition-based stats. Identities = 12/50 (24%), Positives = 24/50 (48%), Gaps = 2/50 (4%) Query: 306 GLVPR--KIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIG 353 GLVPR + +V +G G+MG ++ L+ + + V + + + Sbjct: 13 GLVPRGSHMMEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVE 62 >3TL2-A nrPDB Length = 315 Score = 35.1 bits (79), Expect = 0.11, Method: Composition-based stats. Identities = 20/85 (23%), Positives = 36/85 (42%), Gaps = 11/85 (12%) Query: 313 KKVAIIGGGLMGSGIATALILSNYP-VILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQE 371 KKV++IG G G+ A L V+L ++ + G+ L++ +G Sbjct: 9 KKVSVIGAGFTGATTAFLLAQKELADVVLVDI-PQLENPTKGKALDMLEASPVQGFD--- 64 Query: 372 KFEKTMSLLKGSLDYESFRDVDMVI 396 + + G+ DY D D+V+ Sbjct: 65 ------ANIIGTSDYADTADSDVVV 83 >3TH6-A nrPDB Length = 249 Score = 35.1 bits (79), Expect = 0.12, Method: Composition-based stats. Identities = 29/200 (14%), Positives = 55/200 (27%), Gaps = 20/200 (10%) Query: 60 AKGRFSGGFDISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLE 119 A RF G + G S+D +++ A P + L Sbjct: 2 AARRFCVGGNWKMHGSKNSIRDICNTLKGASLDPNVEVIVACPAPYLDYCRSLLP---PS 58 Query: 120 LAMACHARISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEE-- 177 +A+A E+ G+I GG ++G ++ + + E+ Sbjct: 59 VALAAQNCYKVEQGAFT-GEISPGMIKDCGGQWV---ILGHSERRHVFKEDDVLIGEKIK 114 Query: 178 -GHSLGLIDAVVPPAELVT-----TARRWA----LDIVGRRKPWVSSVSKTDKLPPLGEA 227 GL + + EL+ I K W V + + +G Sbjct: 115 HALESGL-NVIACIGELLEDREAGRTEEVCFRQIKHIASNVKDWSKVVIAYEPVWAIGTG 173 Query: 228 REILTFAKAQTLKRAPNMKH 247 + + + N Sbjct: 174 KTATPDQAQEVHSKVRNWLS 193 >6IHE-A nrPDB Length = 303 Score = 34.7 bits (78), Expect = 0.13, Method: Composition-based stats. Identities = 13/85 (15%), Positives = 34/85 (40%), Gaps = 14/85 (16%) Query: 314 KVAIIGGGLMGSGIATALILSNY--PVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQE 371 KV IG G +G IA + ++S ++ ++ + + ++ ++ K Sbjct: 2 KVGFIGAGKIGQTIAYSALVSGAVDEAVIYDIIPELPDKFEHELRHAFATKGIK------ 55 Query: 372 KFEKTMSLLKGSLDYESFRDVDMVI 396 + + G+ + +D+V+ Sbjct: 56 ------ANVLGTNSLDDVSGMDIVV 74 >1SEZ-A nrPDB Length = 504 Score = 34.7 bits (78), Expect = 0.13, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 26/65 (40%) Query: 313 KKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEK 372 K+VA+IG G+ G A L + V + E K + L +M++ + Sbjct: 14 KRVAVIGAGVSGLAAAYKLKIHGLNVTVFEAEGKAGGKLRSVSQDGLIWDEGANTMTESE 73 Query: 373 FEKTM 377 + T Sbjct: 74 GDVTF 78 >6ABJ-A nrPDB Length = 345 Score = 34.7 bits (78), Expect = 0.14, Method: Composition-based stats. Identities = 23/151 (15%), Positives = 49/151 (32%), Gaps = 14/151 (9%) Query: 313 KKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEK 372 K+V +IG G +G A + ++ + +G L + + + + Sbjct: 161 KRVGVIGTGQIGETFARIMAGFGCELLAYDPYPNPRIQALGGRYLALDALLAESDIVSLH 220 Query: 373 F-----------EKTMSLLKGSLDYESFRDVDMVIEAV-IENISLKQQIFADLEKYCPQH 420 + ++ +K + +V A IE + Q + L+ Y + Sbjct: 221 CPLTADTRHLIDAQRLATMKPGAMLINTGRGALVNAAALIEALKSGQLGYLGLDVYEEEA 280 Query: 421 CILASNTSTIDLNK--IGERTKSQDRIVGAH 449 I + S L + + +V AH Sbjct: 281 DIFFEDRSDQPLQDDVLARLLSFPNVVVTAH 311 >3ZHB-A nrPDB Length = 309 Score = 34.7 bits (78), Expect = 0.15, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 33/77 (42%), Gaps = 7/77 (9%) Query: 315 VAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEKFE 374 V +IG GLMG +A A + + +P + E + R + GS+++ Sbjct: 22 VTVIGLGLMGQALAGAFLGAGHPTTVWNRTAAKAEPLVARGAKS------AGSVAEAVAA 75 Query: 375 KTMSLLKGSLDYESFRD 391 + ++ S DY++ Sbjct: 76 SPLVVVCVS-DYDAVHA 91 >6QGL-A nrPDB Length = 512 Score = 34.7 bits (78), Expect = 0.16, Method: Composition-based stats. Identities = 24/151 (15%), Positives = 44/151 (29%), Gaps = 13/151 (8%) Query: 530 GMPMGPFRLCDLVGFGVAIATATQFIENFSERT-------YKSMIIPLMQEDKRAGEATR 582 G +G + + G GV + + ++ + + + K ++T Sbjct: 6 GYAIGAAAISAVGGIGVGWTLREFEVVGSDDPAEGLTPDVLRNQLSDSVVKRKSNNQSTM 65 Query: 583 KGFYLYDDKRKAKPDPELK----KYIEKARSISGVKLDPKLANLSEKDIIEMTFFPVVNE 638 D + E K + + S S V A S + + F+ NE Sbjct: 66 VDNQNILDGVEHTAYTEAKIAAIEELNAGSSESAVLSAANSAIDSYETTVRTNFYKSWNE 125 Query: 639 ACRVFAEGIAVKAADLDIA--GIMGMGFPPY 667 R A D+ I G P + Sbjct: 126 TVRELEAMTQTVIAHADVGLSYITDFGDPRF 156 >2XD4-A nrPDB Length = 422 Score = 34.3 bits (77), Expect = 0.19, Method: Composition-based stats. Identities = 52/344 (15%), Positives = 114/344 (33%), Gaps = 24/344 (6%) Query: 35 VLYNLKSNYEEA---LSRNDVKAIVITGAKGRFSGGFDISGFGEMQKGNVKEPKAGYISI 91 ++ L +E+A + A +I G+ +F+ D+ ++ + S Sbjct: 74 LIEGLVDEFEKAGLHVFGPSKAAAIIEGS-KQFA--KDLMKKYDIPTAE----YETFTSF 126 Query: 92 DIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISA-----PAAQLGLPELQLGVIP 146 D ++ P V DGLA G G+ +AM I+ + G + + Sbjct: 127 DEAKAYVQEKGAPIVIKADGLAAGKGVTVAMTEEEAIACLHDFLEDEKFGDASASVVIEE 186 Query: 147 GFGGTQR--LPRLVGLTKALEMILTS--KPVKAEEGHSLGLIDAVVPPAELVTTARRWAL 202 G + + + G +I + ++G + G + A P ++ R A+ Sbjct: 187 YLSGEEFSLMAFVKGEKVYPMVIAQDHKRAFDGDKGPNTGGMGAYSPVPQISEETVRHAV 246 Query: 203 DIVGRRKPWVSSVSKTDKLPPLGEAREILTFAKAQTLKRAPNMKHPLMCLDAIEVGIVSG 262 + + + + V + + A +LT ++ ++ P + + S Sbjct: 247 ETIVK-PAAKAMVQEGRSFTGVLYAGLMLTENGSKVIEFNARFGDPET--QVVLPRMESD 303 Query: 263 PRAGLEKEAEVASQVVKLDTTKGLIHVFFSQRGTAKVPGVTDRGLVPRKIKKVAIIGGGL 322 L + ++ T + V S+ T G + + ++V + G Sbjct: 304 LVQVLLDLLDDKEVDLRWKDTAAVSVVLASEGYPESYAKGTPIGSLAAETEQVVVFHAGT 363 Query: 323 MGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKG 366 G + + V ++ EA RV + + G Sbjct: 364 KAEG--GEFVTNGGRVANVTAFDETFEAARDRVYKAVDEIFKPG 405 >5TR3-A nrPDB Length = 481 Score = 34.3 bits (77), Expect = 0.19, Method: Composition-based stats. Identities = 16/69 (23%), Positives = 28/69 (40%), Gaps = 3/69 (4%) Query: 301 GVTDRGLVPRKIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQ 360 G + VP K++ +IG G++G + + V + E + FL A V Q Sbjct: 176 GALEFQAVP---KRLGVIGAGVIGLELGSVWARLGAEVTVLEALDTFLMAADTAVSKEAQ 232 Query: 361 SRVRKGSMS 369 + K + Sbjct: 233 KTLTKQGLD 241 >3LAD-A nrPDB Length = 476 Score = 34.3 bits (77), Expect = 0.19, Method: Composition-based stats. Identities = 14/56 (25%), Positives = 25/56 (44%) Query: 314 KVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMS 369 K+ +IG G++G + + V + E +KFL A +V Q + K + Sbjct: 182 KLGVIGAGVIGLELGSVWARLGAEVTVLEAMDKFLPAVDEQVAKEAQKILTKQGLK 237 >2YQ5-A nrPDB Length = 343 Score = 34.3 bits (77), Expect = 0.20, Method: Composition-based stats. Identities = 10/31 (32%), Positives = 14/31 (45%) Query: 314 KVAIIGGGLMGSGIATALILSNYPVILKEVN 344 V +IG G +GS +A VI +V Sbjct: 150 TVGLIGVGHIGSAVAEIFSAMGAKVIAYDVA 180 >4PRK-A nrPDB Length = 336 Score = 34.3 bits (77), Expect = 0.21, Method: Composition-based stats. Identities = 9/31 (29%), Positives = 15/31 (48%) Query: 313 KKVAIIGGGLMGSGIATALILSNYPVILKEV 343 K + +IG G +GS +A V+ +V Sbjct: 147 KTIGLIGVGHIGSAVAQIFSAMGAKVLAYDV 177 >4K28-A nrPDB Length = 269 Score = 34.3 bits (77), Expect = 0.22, Method: Composition-based stats. Identities = 22/132 (16%), Positives = 45/132 (34%), Gaps = 21/132 (15%) Query: 313 KKVAIIGGGLMGSGIATALILSNY-PVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQE 371 K+ +IG G +GS IA AL + + L + + + A + Sbjct: 126 KRALVIGCGGVGSAIAYALAEAGIASITLCDPSTARMGAVCELLGNG------------- 172 Query: 372 KFEKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQ--IFADLEKYCPQHCILASNTST 429 L S + D D+V A + + + + A L ++A ++ Sbjct: 173 -----FPGLTVSTQFSGLEDFDLVANASPVGMGTRAELPLSAALLATLQPDTLVADVVTS 227 Query: 430 IDLNKIGERTKS 441 ++ + R + Sbjct: 228 PEITPLLNRARQ 239 >3VH2-A nrPDB Length = 616 Score = 33.9 bits (76), Expect = 0.23, Method: Composition-based stats. Identities = 26/130 (20%), Positives = 47/130 (36%), Gaps = 10/130 (7%) Query: 298 KVPGVTDRGLVPRKIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGI----G 353 K + D L K KV ++G G +G ++ ALI I F++ G Sbjct: 313 KWRILPDLNLDIIKNTKVLLLGAGTLGCYVSRALIAWGVRKI------TFVDNGTVSYSN 366 Query: 354 RVKANLQSRVRKGSMSQEKFEKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADL 413 V+ L + G E ++ + +D + +I + N + + F L Sbjct: 367 PVRQALYNFEDCGKPKAELAAASLKRIFPLMDATGVKLSIPMIGHKLVNEEAQHKDFDRL 426 Query: 414 EKYCPQHCIL 423 +H I+ Sbjct: 427 RALIKEHDII 436 >3T7E-A nrPDB Length = 344 Score = 33.9 bits (76), Expect = 0.23, Method: Composition-based stats. Identities = 26/130 (20%), Positives = 47/130 (36%), Gaps = 10/130 (7%) Query: 298 KVPGVTDRGLVPRKIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGI----G 353 K + D L K KV ++G G +G ++ ALI I F++ G Sbjct: 24 KWRILPDLNLDIIKNTKVLLLGAGTLGCYVSRALIAWGVRKI------TFVDNGTVSYSN 77 Query: 354 RVKANLQSRVRKGSMSQEKFEKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADL 413 V+ L + G E ++ + +D + +I + N + + F L Sbjct: 78 PVRQALYNFEDCGKPKAELAAASLKRIFPLMDATGVKLSIPMIGHKLVNEEAQHKDFDRL 137 Query: 414 EKYCPQHCIL 423 +H I+ Sbjct: 138 RALIKEHDII 147 >3X2F-A nrPDB Length = 411 Score = 33.9 bits (76), Expect = 0.23, Method: Composition-based stats. Identities = 28/154 (18%), Positives = 59/154 (38%), Gaps = 9/154 (5%) Query: 265 AGLEKEAEVASQVVKLDTTKGLIHVFFSQRGT--AKVPGVTDRGLVPRKIKKVAIIGGGL 322 LE+ ++ V+ ++ +K + ++F ++ GT + + + K V + G G Sbjct: 149 KALEETGKLRVPVIAVNDSK-MKYLFDNRYGTGQSTWDAIMRNTNLLVAGKNVVVAGYGW 207 Query: 323 MGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEKFEKTMSLLKG 382 G GIA VI+ EV+ + + K ++ F T S Sbjct: 208 CGRGIALRAAGLGARVIVTEVDP---VKAVEAIMDGFTVMPMKEAVKIADFVITASGNTD 264 Query: 383 SLDYES---FRDVDMVIEAVIENISLKQQIFADL 413 L E +D ++ A N+ + ++ ++ Sbjct: 265 VLSKEDILSLKDGAVLANAGHFNVEIPVRVLEEI 298 >4ZGS-A nrPDB Length = 386 Score = 33.9 bits (76), Expect = 0.24, Method: Composition-based stats. Identities = 12/60 (20%), Positives = 23/60 (38%), Gaps = 2/60 (3%) Query: 306 GLVPRKIKK--VAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRV 363 GLV +++ V ++G G +G A L V ++ +G +L + Sbjct: 170 GLVGVEMRHKVVGVVGTGAIGQQAARILKGIGCKVFAYDIKPNPAVEAMGIPYVSLDELL 229 >5N2I-A nrPDB Length = 232 Score = 33.9 bits (76), Expect = 0.26, Method: Composition-based stats. Identities = 19/105 (18%), Positives = 37/105 (35%), Gaps = 20/105 (19%) Query: 299 VPGVTDRGLVPRKIKKVAIIGG-GLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKA 357 + L +A++GG G G G+A ++ + VIL + + +A + Sbjct: 6 ASKSSPHDLPDVSGLSIAVLGGTGDQGRGLARRFAMAGHEVILGSRSAERAQAVAAELGE 65 Query: 358 NLQSRVRKGSMSQEKFEKTMSLLKGSLDYESFRDVDMVIEAVIEN 402 L ++G + + D+VI AV + Sbjct: 66 GLP-------------------VRGMDNAGAAEAGDVVIVAVPWD 91 >3WSV-A nrPDB Length = 322 Score = 33.9 bits (76), Expect = 0.26, Method: Composition-based stats. Identities = 16/83 (19%), Positives = 37/83 (44%), Gaps = 6/83 (7%) Query: 309 PRKIKKVAIIGGGLMGSGIATALILSNY--PVILKEVNEKFLEAG----IGRVKANLQSR 362 + +KV I+G G +G+ IA A+I ++L +VN++ E + + ++ Sbjct: 2 KKTSRKVVIVGTGFVGTSIAYAMINQGVANELVLIDVNQEKAEGEALDLLDGMAWGEKNV 61 Query: 363 VRKGSMSQEKFEKTMSLLKGSLD 385 +E + + +L ++ Sbjct: 62 SVWSGTYEECQDANLVILTAGVN 84 >4E21-A nrPDB Length = 358 Score = 33.9 bits (76), Expect = 0.27, Method: Composition-based stats. Identities = 8/37 (21%), Positives = 20/37 (54%) Query: 314 KVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEA 350 ++ +IG G MG+ + L + ++ ++N ++A Sbjct: 24 QIGMIGLGRMGADMVRRLRKGGHECVVYDLNVNAVQA 60 >4A7P-A nrPDB Length = 446 Score = 33.9 bits (76), Expect = 0.28, Method: Composition-based stats. Identities = 16/87 (18%), Positives = 29/87 (33%), Gaps = 5/87 (5%) Query: 314 KVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEKF 373 ++A+IG G +G + V+ + + I + N+ G + Sbjct: 10 RIAMIGTGYVGLVSGACFSDFGHEVVCVDKD----ARKIELLHQNVMPIYEPGLDALVAS 65 Query: 374 EKTMSLLKGSLDYES-FRDVDMVIEAV 399 L + D +D D V AV Sbjct: 66 NVKAGRLSFTTDLAEGVKDADAVFIAV 92 >6BZ0-A nrPDB Length = 480 Score = 33.5 bits (75), Expect = 0.30, Method: Composition-based stats. Identities = 11/57 (19%), Positives = 24/57 (42%) Query: 313 KKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMS 369 K++ +IG G++G + + V++ E + FL + Q + K + Sbjct: 184 KRLGVIGAGVIGLELGSVWRRLGAEVVVFEAMDAFLPMADKALSKEYQKILTKQGLD 240 >5O3Z-A nrPDB Length = 263 Score = 33.5 bits (75), Expect = 0.30, Method: Composition-based stats. Identities = 19/91 (20%), Positives = 41/91 (45%), Gaps = 3/91 (3%) Query: 308 VPRKIKKVAI-IGGG-LMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRK 365 +++VA+ IGGG +G+ + L + Y V + ++NE + + + Sbjct: 1 GAMAMEQVAVVIGGGQTLGAFLCEGLAQAGYHVAVADLNESNANRLADTINSRYGAGRAY 60 Query: 366 GSMSQEKFEKTMSLLKGSLDYESFRDVDMVI 396 G E ++ L ++D E+F D+++ Sbjct: 61 GFKVDATDEASVEALARAVD-ETFGRADLLV 90 >4MOP-A nrPDB Length = 633 Score = 33.5 bits (75), Expect = 0.32, Method: Composition-based stats. Identities = 14/53 (26%), Positives = 27/53 (50%), Gaps = 3/53 (5%) Query: 303 TDRGLVPRKIK-KVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGR 354 D+ + IK V I+G G +G A L+ + Y V + ++ E +++G+ Sbjct: 36 PDKKVPGMDIKYDVVIVGSGPIGCTYARELVGAGYKVAMFDIGE--IDSGLKI 86 >3G5Q-A nrPDB Length = 443 Score = 33.5 bits (75), Expect = 0.32, Method: Composition-based stats. Identities = 24/88 (27%), Positives = 36/88 (40%), Gaps = 6/88 (6%) Query: 312 IKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQE 371 +++V ++G GL GS A L+ PV L E+ K + G V S+ E Sbjct: 1 MERVNVVGAGLAGSEAAWTLLRLGVPVRLFEMRPKRMTPAHG--TDRFAEIVCSNSLGGE 58 Query: 372 KFEKTMSLLKGSLDYESFRDVDMVIEAV 399 LL+ E R +V+EA Sbjct: 59 GETNAKGLLQ----AEMRRAGSLVMEAA 82 >2V3B-A nrPDB Length = 384 Score = 33.5 bits (75), Expect = 0.32, Method: Composition-based stats. Identities = 20/94 (21%), Positives = 37/94 (39%), Gaps = 7/94 (7%) Query: 313 KKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFL-----EAGIGRVKANLQSRVRKGS 367 ++V ++G GL+G A L Y + + E+ + A V+A L+ + Sbjct: 146 RRVLLLGAGLIGCEFANDLSSGGYQLDVVAPCEQVMPGLLHPAAAKAVQAGLEGLGVRFH 205 Query: 368 MSQ--EKFEKTMSLLKGSLDYESFRDVDMVIEAV 399 + +K L+ L D+V+ AV Sbjct: 206 LGPVLASLKKAGEGLEAHLSDGEVIPCDLVVSAV 239 >3KB6-A nrPDB Length = 334 Score = 33.5 bits (75), Expect = 0.33, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 33/74 (44%), Gaps = 2/74 (2%) Query: 293 QRGTAKVPGVTDRGLVPRKIKKV--AIIGGGLMGSGIATALILSNYPVILKEVNEKFLEA 350 + K+ D ++ R++ ++ +IG G +GS +A + V+ +V ++ Sbjct: 120 EDRVKKLNFSQDSEILARELNRLTLGVIGTGRIGSRVAMYGLAFGMKVLCYDVVKREDLK 179 Query: 351 GIGRVKANLQSRVR 364 G V +L ++ Sbjct: 180 EKGCVYTSLDELLK 193 >5X68-A nrPDB Length = 391 Score = 33.5 bits (75), Expect = 0.34, Method: Composition-based stats. Identities = 30/156 (19%), Positives = 56/156 (35%), Gaps = 22/156 (14%) Query: 298 KVPGVTDRGLVPRKIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKA 357 + G D ++ R KKVA+IGGGL+GS A L N+ + + E E A R ++ Sbjct: 2 RGSGSMDSSVIQR--KKVAVIGGGLVGSLQACFLAKRNFQIDVYEAREDTRVATFTRGRS 59 Query: 358 NLQSRVRKGSMSQEKFEKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADLEKY- 416 + +G + + D +V + + + + Sbjct: 60 INLALSHRGRQALKAV--------------GLED-QIVSQGIPMRARMIHSLSGKKSAIP 104 Query: 417 --CPQHCILASNTSTIDLNKIGERTKSQDRIVGAHF 450 IL+ + ++ + + K + V HF Sbjct: 105 YGTKSQYILSVSRENLNKDLLTAAEKYPN--VKMHF 138 >4UEJ-A nrPDB Length = 346 Score = 33.5 bits (75), Expect = 0.36, Method: Composition-based stats. Identities = 22/116 (18%), Positives = 41/116 (35%), Gaps = 18/116 (15%) Query: 287 IHVFFSQRGTAKVPGVTDRGLVPRKIKKVAIIGGGLMG-SGIATALILSNYPVILKEVNE 345 +H F +G K V IIG G +G I A+ L V +++ Sbjct: 150 LHAFHLAQGCEN--------------KNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISS 195 Query: 346 KFLEAGIGRVKANLQSRVRKGSMSQEKFEKTMSLLKGSLDYESFRDVDMVIEAVIE 401 + L + + +Q+ MS + + + L+ + V +E +E Sbjct: 196 EKL--ALAKSFGAMQTFNSSE-MSAPQMQSVLRELRFNQLILETAGVPQTVELAVE 248 >5JFC-L nrPDB Length = 474 Score = 33.5 bits (75), Expect = 0.37, Method: Composition-based stats. Identities = 15/35 (42%), Positives = 17/35 (48%) Query: 308 VPRKIKKVAIIGGGLMGSGIATALILSNYPVILKE 342 + R KKVAIIG G G A L Y V + E Sbjct: 150 IKRNGKKVAIIGAGPAGLTCAADLAKMGYEVTIYE 184 >3ZZN-A nrPDB Length = 310 Score = 33.5 bits (75), Expect = 0.37, Method: Composition-based stats. Identities = 15/44 (34%), Positives = 24/44 (54%), Gaps = 2/44 (4%) Query: 314 KVAIIGGGLMGSGIATALILSNY--PVILKEVNEKFLEAGIGRV 355 KV I+G G++GS A AL L V+L +++ K +A + Sbjct: 2 KVGIVGSGMVGSATAYALALLGVAREVVLVDLDRKLAQAHAEDI 45 >5VJ7-A nrPDB Length = 476 Score = 33.1 bits (74), Expect = 0.38, Method: Composition-based stats. Identities = 15/35 (42%), Positives = 17/35 (48%) Query: 308 VPRKIKKVAIIGGGLMGSGIATALILSNYPVILKE 342 + R KKVAIIG G G A L Y V + E Sbjct: 150 IKRNGKKVAIIGAGPAGLTCAADLAKMGYEVTIYE 184 >5MH6-A nrPDB Length = 308 Score = 33.1 bits (74), Expect = 0.40, Method: Composition-based stats. Identities = 6/38 (15%), Positives = 16/38 (42%) Query: 313 KKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEA 350 ++V ++G G +G G+ V+ + ++ Sbjct: 136 ERVCVVGLGTLGRGVVDRAAALGMEVVGVRRSGDPVDN 173 >4FFM-A nrPDB Length = 363 Score = 33.1 bits (74), Expect = 0.43, Method: Composition-based stats. Identities = 10/39 (25%), Positives = 18/39 (46%) Query: 312 IKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEA 350 +K + ++GG L G A + V+L + N + L Sbjct: 1 MKTICLVGGKLQGFEAAYLSKKAGMKVVLVDKNPQALIR 39 >1GPJ-A nrPDB Length = 404 Score = 33.1 bits (74), Expect = 0.46, Method: Composition-based stats. Identities = 27/153 (17%), Positives = 48/153 (31%), Gaps = 7/153 (4%) Query: 250 MCLDAIEVGIVSGPRAGLEKEAEVASQVVKLDTTKGLIHVFFSQRGTAKVPGVT----DR 305 L ++ R G EA ++ K G + +R Sbjct: 101 EILRQVKKAYDRAARLGTLDEALKIVFRRAINLGKRAREETRISEGAVSIGSAAVELAER 160 Query: 306 GLVPRKIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRK 365 L K V ++G G MG +A +L+ +L V + E + + VR Sbjct: 161 ELGSLHDKTVLVVGAGEMGKTVAKSLVDRGVRAVL--VANRTYERAVELARDLGGEAVRF 218 Query: 366 GSMSQEKFEKTMSLLKGSLDYESFRDVDMVIEA 398 + ++ ++ + VD V EA Sbjct: 219 DELVDH-LARSDVVVSATAAPHPVIHVDDVREA 250 >3NJ4-A nrPDB Length = 435 Score = 33.1 bits (74), Expect = 0.46, Method: Composition-based stats. Identities = 32/172 (18%), Positives = 64/172 (37%), Gaps = 35/172 (20%) Query: 314 KVAII-GGGLMGSGIATALILSNYPVILKEVNE-KFLEAGIGRVK-ANLQSRVRKGSM-- 368 KVA++ G G +G G A AL VI+ E++ L+A + + + ++G++ Sbjct: 217 KVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQEGNIFV 276 Query: 369 -SQEKFEKTMSL---------LKGSLDYESFR-DVDMVIEAVIENISLKQQI-------- 409 + + + + ++ + DV + E +E +++K Q+ Sbjct: 277 TTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYRLKNG 336 Query: 410 ----------FADLEKYCPQHCILASNTSTIDLNKIGERTKSQDRI-VGAHF 450 +L + SN+ T + E D+ VG HF Sbjct: 337 RRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHF 388 >1Q1R-A nrPDB Length = 431 Score = 33.1 bits (74), Expect = 0.47, Method: Composition-based stats. Identities = 20/145 (13%), Positives = 44/145 (30%), Gaps = 29/145 (20%) Query: 262 GPRAGLEKEAEVASQVVKLDTTKGLIHVFFSQRGTAKVPGVTDRGLVPRKIKKVAIIGGG 321 +G +A + L+ + + + ++ +IGGG Sbjct: 118 PVASGAVGKANNFRYLRTLEDAECIRRQLIAD-------------------NRLVVIGGG 158 Query: 322 LMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEKFEKTMSLLK 381 +G +A I +N V L + + LE + + + + + + + Sbjct: 159 YIGLEVAATAIKANMHVTLLDTAARVLERVTAPPVSAFYEHLHREAGVDIRTGTQVCGFE 218 Query: 382 GSLDYESFRD----------VDMVI 396 S D + D+VI Sbjct: 219 MSTDQQKVTAVLCEDGTRLPADLVI 243 >3HWR-A nrPDB Length = 318 Score = 33.1 bits (74), Expect = 0.48, Method: Composition-based stats. Identities = 18/86 (20%), Positives = 33/86 (38%), Gaps = 12/86 (13%) Query: 314 KVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEKF 373 KVAI+G G +G L + + VIL + I + + F Sbjct: 21 KVAIMGAGAVGCYYGGMLARAGHEVIL--IARPQHVQAIE---------ATGLRLETQSF 69 Query: 374 EKTMSLLKGSLDYESFRDVDMVIEAV 399 ++ + + S D + + D+V+ V Sbjct: 70 DEQVK-VSASSDPSAVQGADLVLFCV 94 >1XDW-A nrPDB Length = 331 Score = 33.1 bits (74), Expect = 0.48, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 30/73 (41%), Gaps = 2/73 (2%) Query: 275 SQVVKLDTTKGLIHVFFSQRGTAKVPGVTDRGLVPRKIKK--VAIIGGGLMGSGIATALI 332 +++ L H ++ TAK D + ++++ V ++G G +G A Sbjct: 107 AELAVTQAMMLLRHTAYTTSRTAKKNFKVDAFMFSKEVRNCTVGVVGLGRIGRVAAQIFH 166 Query: 333 LSNYPVILKEVNE 345 VI ++V E Sbjct: 167 GMGATVIGEDVFE 179 >5UYY-A nrPDB Length = 381 Score = 32.8 bits (73), Expect = 0.54, Method: Composition-based stats. Identities = 14/60 (23%), Positives = 29/60 (48%), Gaps = 4/60 (6%) Query: 297 AKVPGVTDRGLVPRKI-KKVAIIGGGLMGSGIATALILSNYPVIL--KEVNEKFLEAGIG 353 + + L R++ KKV +IG GL+G +A I ++ V + ++ ++ +E Sbjct: 1 SNAMKIKKESLEMRQMRKKVVLIGTGLIGGSLA-LAIKKDHDVTITGYDIFQEQVERAKE 59 >1OC4-A nrPDB Length = 322 Score = 32.8 bits (73), Expect = 0.54, Method: Composition-based stats. Identities = 16/84 (19%), Positives = 35/84 (41%), Gaps = 13/84 (15%) Query: 314 KVAIIGGGLMGSGIATALILSNY-PVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEK 372 K+ ++G G++G +AT ++ N V++ + + N+ + Sbjct: 6 KIVLVGSGMIGGVMATLIVQKNLGDVVMFD------------IVKNMPHGKALDTSHTNV 53 Query: 373 FEKTMSLLKGSLDYESFRDVDMVI 396 + + GS Y+ +D D+VI Sbjct: 54 MAYSNCKVSGSNTYDDLKDADVVI 77 >2EW2-A nrPDB Length = 316 Score = 32.8 bits (73), Expect = 0.56, Method: Composition-based stats. Identities = 19/86 (22%), Positives = 30/86 (34%), Gaps = 14/86 (16%) Query: 314 KVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEKF 373 K+AI G G MGS + L V L + +EA G ++ Sbjct: 5 KIAIAGAGAMGSRLGIMLHQGGNDVTLIDQWPAHIEAIRKN-----------GLIADFNG 53 Query: 374 EKTMSLL---KGSLDYESFRDVDMVI 396 E+ ++ L VD++I Sbjct: 54 EEVVANLPIFSPEEIDHQNEQVDLII 79 >4ZCC-A nrPDB Length = 336 Score = 32.8 bits (73), Expect = 0.57, Method: Composition-based stats. Identities = 11/30 (36%), Positives = 17/30 (56%) Query: 315 VAIIGGGLMGSGIATALILSNYPVILKEVN 344 +AIIG G+ G A AL + + V L + + Sbjct: 5 IAIIGTGIAGLSAAQALTSAGHQVHLFDKS 34 >3GSZ-A nrPDB Length = 563 Score = 32.8 bits (73), Expect = 0.57, Method: Composition-based stats. Identities = 9/56 (16%), Positives = 18/56 (32%) Query: 669 GGIMFWADSIGSKYIYSRLDEWSKAYGEFFKPCAFLAERGSKGVLLSAPVKQASSR 724 G ++ + + I RL + P + L + P++ SR Sbjct: 448 YGAVYSVNPLDLPAIIERLHGLEAFSLHTYSPHELSRVAATLRKLGAPPLRAWKSR 503 >4OX3-A nrPDB Length = 219 Score = 32.8 bits (73), Expect = 0.60, Method: Composition-based stats. Identities = 29/152 (19%), Positives = 53/152 (34%), Gaps = 6/152 (3%) Query: 513 VECGADPYLIDRAISKFGMPMGPFRLCDLVGFGVAIATATQFIENFSERTYKSMIIPLMQ 572 +E +P I ++K G + DLV V + + + + + + + Sbjct: 21 LETIQNPENILALVNKQYALPGNYEPSDLVIPDVEFSFEEKIQKRYIRKEAADALKTMFD 80 Query: 573 EDKRAG--EATRKGFYLYDDKRKAKPDPELKKYIEKARSISGVKLDPKLANLSEKDIIEM 630 K+ G A G+ YD ++ + K KA+ + + DI Sbjct: 81 AAKKEGYELAAVSGYRSYDRQKVIFDNEVSLKGERKAKEAVAYPGESEHQTGLAMDISSR 140 Query: 631 TFFPVVNEACRVFAEGIAVKAADLDIAGIMGM 662 + +NEA A+G V+ D A G Sbjct: 141 SNGFELNEAFGSTADGKWVQ----DNAYKYGF 168 >3ATQ-A nrPDB Length = 453 Score = 32.8 bits (73), Expect = 0.60, Method: Composition-based stats. Identities = 11/31 (35%), Positives = 14/31 (45%) Query: 315 VAIIGGGLMGSGIATALILSNYPVILKEVNE 345 V IIGGG GS A L ++L + Sbjct: 9 VLIIGGGFAGSSAAYQLSRRGLKILLVDSKP 39 >3PEF-A nrPDB Length = 287 Score = 32.4 bits (72), Expect = 0.74, Method: Composition-based stats. Identities = 11/37 (29%), Positives = 19/37 (51%) Query: 313 KKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLE 349 +K IG G+MGS +A L+ + V + + + E Sbjct: 2 QKFGFIGLGIMGSAMAKNLVKAGCSVTIWNRSPEKAE 38 >3FG2-P nrPDB Length = 404 Score = 32.4 bits (72), Expect = 0.74, Method: Composition-based stats. Identities = 9/38 (23%), Positives = 15/38 (39%) Query: 313 KKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEA 350 K V +IG G +G A V + E+ + + Sbjct: 143 KHVVVIGAGFIGLEFAATARAKGLEVDVVELAPRVMAR 180 >3AXS-A nrPDB Length = 392 Score = 32.4 bits (72), Expect = 0.74, Method: Composition-based stats. Identities = 23/158 (14%), Positives = 46/158 (29%), Gaps = 12/158 (7%) Query: 545 GVAIATATQFIENFSERTYKSMIIPLM-QEDKRAGEAT-RKGFYLYDDKRKAKPDPELKK 602 ++ ENF + E GF D P P ++ Sbjct: 84 DISSKAIEIMKENFKLNNIPEDRYEIHGMEANFFLRKEWGFGFDYVDLDPFGTPVPFIES 143 Query: 603 YIEKAR-----SISGVKLDPKLANLSEKDIIEMTFFPVVNE-----ACRVFAEGIAVKAA 652 + S++ P + + P+ NE R+ + + AA Sbjct: 144 VALSMKRGGILSLTATDTAPLSGTYPKTCMRRYMARPLRNEFKHEVGIRILIKKVIELAA 203 Query: 653 DLDIAGIMGMGFPPYRGGIMFWADSIGSKYIYSRLDEW 690 DIA I + +F+ G + + ++++ Sbjct: 204 QYDIAMIPIFAYSHLHYFKLFFVKERGVEKVDKLIEQF 241 >2AVN-A nrPDB Length = 260 Score = 32.4 bits (72), Expect = 0.80, Method: Composition-based stats. Identities = 18/111 (16%), Positives = 41/111 (36%), Gaps = 20/111 (18%) Query: 314 KVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKAN-LQSRVRKGSMSQEK 372 +V +GGG + L + V+L + +++ LE + N ++++ Sbjct: 57 RVLDLGGGT--GKWSLFLQERGFEVVLVDPSKEMLEVAREKGVKNVVEAKAEDLPFPSGA 114 Query: 373 FEKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADLEKYCPQHCIL 423 FE ++ DV +E K + F+++ + +L Sbjct: 115 FEAVLA----------LGDVLSYVEN-------KDKAFSEIRRVLVPDGLL 148 >5JXW-A nrPDB Length = 498 Score = 32.4 bits (72), Expect = 0.84, Method: Composition-based stats. Identities = 14/56 (25%), Positives = 27/56 (48%), Gaps = 1/56 (1%) Query: 313 KKVAIIGGGLMGSGIATALILSNYPVILKEVNEK-FLEAGIGRVKANLQSRVRKGS 367 KK+ ++G G +G G A L VI+ E++ L+A + + ++ V + Sbjct: 272 KKIVVLGYGEVGKGCAQGLSGVGARVIVTEIDPICALQASMEGYQVSVLEDVVSEA 327 >3KKJ-A nrPDB Length = 336 Score = 32.4 bits (72), Expect = 0.84, Method: Composition-based stats. Identities = 11/30 (36%), Positives = 17/30 (56%) Query: 315 VAIIGGGLMGSGIATALILSNYPVILKEVN 344 +AIIG G+ G A AL + + V L + + Sbjct: 5 IAIIGTGIAGLSAAQALTAAGHQVHLFDKS 34 >1AHH-A nrPDB Length = 255 Score = 32.0 bits (71), Expect = 0.84, Method: Composition-based stats. Identities = 13/85 (15%), Positives = 32/85 (37%), Gaps = 6/85 (7%) Query: 317 IIGGGL-MGSGIATALILSNYPVILKEVNEKFLEAGIGRVKA-NLQSRVRKGSMSQEKFE 374 I G G +G IA + V++ ++N + ++ Q+ + ++ E+ Sbjct: 16 ITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSEQEL 75 Query: 375 KTMSLLKGSLDYESFRDVDMVIEAV 399 ++ S VD+++ Sbjct: 76 SALADFAIS----KLGKVDILVNNA 96 >3KYB-A nrPDB Length = 390 Score = 32.0 bits (71), Expect = 0.88, Method: Composition-based stats. Identities = 9/34 (26%), Positives = 16/34 (47%) Query: 313 KKVAIIGGGLMGSGIATALILSNYPVILKEVNEK 346 KK+ I+G G G+ I L + V + + + Sbjct: 4 KKILIVGAGFSGAVIGRQLAEKGHQVHIIDQRDH 37 >5ZIK-A nrPDB Length = 303 Score = 32.0 bits (71), Expect = 0.90, Method: Composition-based stats. Identities = 27/125 (21%), Positives = 46/125 (36%), Gaps = 17/125 (13%) Query: 317 IIGGGLMGSGIATALILSNYPVILKEVNEKFLEA-----GIGRVKANLQSRVRKGSMSQE 371 I+G G +GS A L + PV L + + L G+ V+ S + + + Sbjct: 5 ILGAGSLGSLWAARLGRAGLPVRLILRDRQRLRRYQQAGGLSLVEDGQASLYPIAAETPD 64 Query: 372 KFEKTMSLLKGSLDYESFRDVDMVIEAVIENISL---------KQQIFADLEKYCPQHCI 422 + LL Y++ V + N L +Q + A L + C+ Sbjct: 65 GGQPIQRLLLACKAYDAEEAASSVAHRLAGNAELLLLQNGLGSQQAVAARLPR---SRCL 121 Query: 423 LASNT 427 AS+T Sbjct: 122 FASST 126 >6CI9-A nrPDB Length = 259 Score = 32.0 bits (71), Expect = 0.91, Method: Composition-based stats. Identities = 10/58 (17%), Positives = 23/58 (39%), Gaps = 6/58 (10%) Query: 319 GGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEKFEKT 376 G +G GIA + V++ N+ L+ + + +G ++ + + T Sbjct: 17 GSKGIGRGIAETFANAGVDVVITGRNQDDLDRTVADLSGT------RGKVTAVRADVT 68 >4DLA-A nrPDB Length = 396 Score = 32.0 bits (71), Expect = 0.93, Method: Composition-based stats. Identities = 10/54 (18%), Positives = 18/54 (33%), Gaps = 1/54 (1%) Query: 301 GVTDRGLVPRKIKKVAIIGGGLMGSGIAT-ALILSNYPVILKEVNEKFLEAGIG 353 G VA+ G G +G +A A +I +++ K + Sbjct: 201 GAVWNTAKVEPGSIVAVFGLGTVGLAVAEGAKAAGASRIIGIDIDSKKFDRAKN 254 >1Y6J-A nrPDB Length = 318 Score = 32.0 bits (71), Expect = 0.96, Method: Composition-based stats. Identities = 23/87 (26%), Positives = 36/87 (41%), Gaps = 18/87 (20%) Query: 313 KKVAIIGGGLMGSGIATALIL--SNYPVILKEV-NEKFLEAGIGRVKANLQSRVRKGSMS 369 KVAIIG G +G+ A + L + ++L +V EK + + Sbjct: 8 SKVAIIGAGFVGASAAFTMALRQTANELVLIDVFKEKAIGEAMDINH------------- 54 Query: 370 QEKFEKTMSLLKGSLDYESFRDVDMVI 396 F MSL G DY +D D+++ Sbjct: 55 GLPFMGQMSLYAG--DYSDVKDCDVIV 79 >3EEQ-A nrPDB Length = 336 Score = 32.0 bits (71), Expect = 0.99, Method: Composition-based stats. Identities = 12/61 (19%), Positives = 23/61 (37%), Gaps = 2/61 (3%) Query: 53 KAIVITGAKGRFSGGFDISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGL 112 +I+ ++ FS G I + + V + I+ I +A V A++G Sbjct: 10 GICIISASEDAFSAGETIKEKLKSFEIPVVHYRYKDAEIETIWKCYDAI--VFVMALEGA 67 Query: 113 A 113 Sbjct: 68 T 68 >4JJI-A nrPDB Length = 378 Score = 32.0 bits (71), Expect = 1.00, Method: Composition-based stats. Identities = 17/88 (19%), Positives = 28/88 (31%), Gaps = 4/88 (4%) Query: 301 GVTDRGLVPRKIKKVAIIGGGLMGSGIATALILSNY-PVILKEVNEKFLEAGIGRVKANL 359 G VAI G G +G +A + +I +++ K E + Sbjct: 183 GAVWNTAKVEPGSNVAIFGLGTVGLAVAEGAKTAGASRIIGIDIDSKKYETAKK---FGV 239 Query: 360 QSRVRKGSMSQEKFEKTMSLLKGSLDYE 387 V + E + L G +DY Sbjct: 240 NEFVNPKDHDKPIQEVIVDLTDGGVDYS 267 >4CPD-A nrPDB Length = 347 Score = 32.0 bits (71), Expect = 1.0, Method: Composition-based stats. Identities = 30/146 (20%), Positives = 52/146 (35%), Gaps = 21/146 (14%) Query: 258 GIVSGPRAGLEKEAEVASQVVKLDTTKGLIHVFFSQRGTAKVPGVTDRGLVPRKIKKVAI 317 G + G +A + + + KL F+ + G +G + R VA+ Sbjct: 116 GNLQGAQAEILRVPFSNVNLRKLPPNLSPERAIFAGDILSTAYGGLIQGQL-RPGDSVAV 174 Query: 318 IGG---GLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMS-QEKF 373 IG GLM +A L S I R+ L+ G++ + Sbjct: 175 IGAGPVGLMAIEVAQVLGASKI-------------LAIDRIPERLERAASLGAIPINAEQ 221 Query: 374 EKTMSLLKGSLDYESFRDVDMVIEAV 399 E + ++ + E D+V+EAV Sbjct: 222 ENPVRRVRSETNDE---GPDLVLEAV 244 >1YB4-A nrPDB Length = 295 Score = 32.0 bits (71), Expect = 1.0, Method: Composition-based stats. Identities = 34/233 (14%), Positives = 78/233 (33%), Gaps = 46/233 (19%) Query: 314 KVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEKF 373 K+ IG G+MGS +A L + + + + + + G+++ E Sbjct: 5 KLGFIGLGIMGSPMAINLARAGHQLHVTTIGPVA------------DELLSLGAVNVETA 52 Query: 374 EKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFAD---LEKYCPQHCILASNTSTI 430 + D++ V + ++ +F + + I+ + S+I Sbjct: 53 RQV------------TEFADIIFIMVPDTPQVEDVLFGEHGCAKTSLQGKTIV--DMSSI 98 Query: 431 DLNKIGERTKSQDRIVGAHFFSPAHIMPL------LEIVRTNHTSAQVIVDLLDVGKKIK 484 + + + + + +P + L I+ +V + + + Sbjct: 99 SPIETKRFAQRVNEMGADYLDAPVSGGEIGAREGTLSIMVGGE--QKVFDRVKPLFDILG 156 Query: 485 KTPVVV-GNCTGF---AVNRMFFPYTQAA-----MFLVECGADPYLIDRAISK 528 K +V GN G N++ A +F + GADP + +A+ Sbjct: 157 KNITLVGGNGDGQTCKVANQIIVALNIEAVSEALVFASKAGADPVRVRQALMG 209 >4A6N-B nrPDB Length = 398 Score = 32.0 bits (71), Expect = 1.0, Method: Composition-based stats. Identities = 13/38 (34%), Positives = 18/38 (47%) Query: 313 KKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEA 350 K VAIIGGG +G +A L + V + E + Sbjct: 27 KNVAIIGGGPVGLTMAKLLQQNGIDVSVYERDNDREAR 64 >1LSS-A nrPDB Length = 140 Score = 32.0 bits (71), Expect = 1.1, Method: Composition-based stats. Identities = 21/100 (21%), Positives = 42/100 (42%), Gaps = 17/100 (17%) Query: 315 VAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEKFE 374 + I G G +G +A +L + ++L ++++ + A + + V G ++ K Sbjct: 7 IIIAGIGRVGYTLAKSLSEKGHDIVLIDIDKDICKKA----SAEIDALVINGDCTKIK-- 60 Query: 375 KTMSLLKGSLDYESFRDVDMVIEAVI--ENISLKQQIFAD 412 +L+ D DM I AV E ++L + A Sbjct: 61 --------TLEDAGIEDADMYI-AVTGKEEVNLMSSLLAK 91 >3WFI-A nrPDB Length = 312 Score = 31.6 bits (70), Expect = 1.1, Method: Composition-based stats. Identities = 30/126 (23%), Positives = 52/126 (41%), Gaps = 12/126 (9%) Query: 314 KVAIIGGGLMGSGIATALILSNYPVILKE--------VNEKFLEAGI--GRVKANLQSRV 363 K+AI G G MGS L S V+L + + E L+A V+A L + Sbjct: 2 KIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGLQANFNGKEVEAKLPIVL 61 Query: 364 RKGSMSQEKFEKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFAD--LEKYCPQHC 421 + +++ + + K + +D+ +I+ E + L I + +EK+ P Sbjct: 62 QSEVEKEDQVDLIILFTKAMQLEKMLQDIQSLIKKDTEVLCLLNGIGHEDIIEKFVPMEN 121 Query: 422 ILASNT 427 I NT Sbjct: 122 IYIGNT 127 >3BHF-A nrPDB Length = 390 Score = 31.6 bits (70), Expect = 1.1, Method: Composition-based stats. Identities = 7/28 (25%), Positives = 11/28 (39%) Query: 315 VAIIGGGLMGSGIATALILSNYPVILKE 342 V ++G G MG L +L + Sbjct: 7 VIVVGAGSMGMAAGYQLAKQGVKTLLVD 34 >3ENK-A nrPDB Length = 341 Score = 31.6 bits (70), Expect = 1.1, Method: Composition-based stats. Identities = 11/62 (17%), Positives = 25/62 (40%), Gaps = 1/62 (1%) Query: 319 GGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEKFEKTMS 378 G G +GS A L+ Y V++ + I R++ + + + E+ ++ Sbjct: 13 GAGYIGSHTAVELLAHGYDVVIADNLVNSKREAIARIEK-ITGKTPAFHETDVSDERALA 71 Query: 379 LL 380 + Sbjct: 72 RI 73 >3U9S-B nrPDB Length = 555 Score = 31.6 bits (70), Expect = 1.2, Method: Composition-based stats. Identities = 32/233 (13%), Positives = 53/233 (22%), Gaps = 61/233 (26%) Query: 65 SGGFDISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMAC 124 SGG ++ E+ + + ++ + P +A + G GG + Sbjct: 165 SGGANLPRQDEVFPDREHFGRIFFNQANMSARGI-----PQIAVVMGSCTAGGAYVPAMS 219 Query: 125 HARISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEE------- 177 + Q L G T + V AEE Sbjct: 220 DETVMVRE-------------------QATIFLAGPPLVKAA--TGEVVSAEELGGADVH 258 Query: 178 GHSLGLIDAVVPPAELVTTARRWALDIVGRRKPWVSSVSKTDKLPPLGEAREILTFAKAQ 237 G+ D + A A V + K +L Sbjct: 259 CKVSGVADHYAEDDD---HALAIARRCVA-----NLNWRKQGQLQCRAP----------- 299 Query: 238 TLKRAPNMKHPLMCLDAIEVGIVSGPRAGLEKEAEVASQVVKLDTTKGLIHVF 290 RAP I EV +++V +F Sbjct: 300 ---RAPLYPA-EELYGVIPADSKQPYDV-----REVIARLVDGSEFDEFKALF 343 >3Q3C-A nrPDB Length = 299 Score = 31.6 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 11/39 (28%), Positives = 25/39 (64%) Query: 312 IKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEA 350 +K++A IG G MG+ +AT L+ + Y + + ++ + ++ Sbjct: 2 MKQIAFIGLGHMGAPMATNLLKAGYLLNVFDLVQSAVDG 40 >2V8U-A nrPDB Length = 302 Score = 31.6 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 12/57 (21%), Positives = 22/57 (38%), Gaps = 4/57 (7%) Query: 31 LSFDVLYNLKSNYEEALSRNDVKAIVITG---AKGRFSGGFDISGFG-EMQKGNVKE 83 S + +L ++ A + + +V+ G F G D + F E G + E Sbjct: 236 FSPEDYRDLGLIWKGASPEDGTEVVVVDGPPTGGPVFDAGHDAAEFAPEFHPGELYE 292 >5T5Q-A nrPDB Length = 247 Score = 31.6 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 17/88 (19%), Positives = 38/88 (43%), Gaps = 5/88 (5%) Query: 313 KKVAIIGG-GLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQE 371 + + + G G +G IA S ++L +++ + L+A A+L S R ++ + Sbjct: 10 RTLVLTGANGGIGRAIAELFHASGANLVLTDLDREGLDA----FAASLGSPERIATIKAD 65 Query: 372 KFEKTMSLLKGSLDYESFRDVDMVIEAV 399 + +L E F +D ++ + Sbjct: 66 ASSADDAEKTVALAMERFGGIDFLVPSA 93 >5OCM-A nrPDB Length = 291 Score = 31.6 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 9/31 (29%), Positives = 16/31 (51%) Query: 315 VAIIGGGLMGSGIATALILSNYPVILKEVNE 345 V ++G GLMG +A A + + + +E Sbjct: 6 VTVLGLGLMGQALAGAFLKDGHATTVWNRSE 36 >3PDU-A nrPDB Length = 287 Score = 31.6 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 8/38 (21%), Positives = 16/38 (42%) Query: 312 IKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLE 349 + +G G+MG +A L+ + + V + N Sbjct: 1 MTTYGFLGLGIMGGPMAANLVRAGFDVTVWNRNPAKCA 38 >3LXD-A nrPDB Length = 415 Score = 31.6 bits (70), Expect = 1.4, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 23/70 (32%) Query: 313 KKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEK 372 K +IGGG +G A L V L E + L G + + + Sbjct: 153 KNAVVIGGGYIGLEAAAVLTKFGVNVTLLEALPRVLARVAGEALSEFYQAEHRAHGVDLR 212 Query: 373 FEKTMSLLKG 382 M ++G Sbjct: 213 TGAAMDCIEG 222 >3DC2-A nrPDB Length = 529 Score = 31.6 bits (70), Expect = 1.4, Method: Composition-based stats. Identities = 8/44 (18%), Positives = 17/44 (38%) Query: 313 KKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVK 356 K V ++G G +G +A + V+ + A ++ Sbjct: 143 KTVGVVGLGRIGQLVAQRIAAFGAYVVAYDPYVSPARAAQLGIE 186 >2CZG-A nrPDB Length = 433 Score = 31.6 bits (70), Expect = 1.4, Method: Composition-based stats. Identities = 7/37 (18%), Positives = 14/37 (37%) Query: 306 GLVPRKIKKVAIIGGGLMGSGIATALILSNYPVILKE 342 +K+ ++G G +G IA V+ + Sbjct: 13 TATTDSAQKILLLGSGELGKEIAIEAQRLGVEVVAVD 49 >3N58-A nrPDB Length = 464 Score = 31.2 bits (69), Expect = 1.5, Method: Composition-based stats. Identities = 25/139 (17%), Positives = 48/139 (34%), Gaps = 5/139 (3%) Query: 223 PLGEAREILTFAKAQTLKRAPNM-KHPLMCLDAIEVGIVSGPRAGLEKEAEVASQVVKLD 281 P E E+L + + P + + +G + + + ++ Sbjct: 154 PQSEEEEVLFAQIKKRMAATPGFFTKQRAAIKGVTEETTTGVNRLYQLQKKGLLPFPAIN 213 Query: 282 TTKGLIHVFFSQRGTAKVPGVT--DRGLVPRKIKKVAII-GGGLMGSGIATALILSNYPV 338 + F + K V RG KVA++ G G +G G A +L + V Sbjct: 214 VNDSVTKSKFDNKYGCKESLVDGIRRGTDVMMAGKVAVVCGYGDVGKGSAQSLAGAGARV 273 Query: 339 ILKEVNEK-FLEAGIGRVK 356 + EV+ L+A + + Sbjct: 274 KVTEVDPICALQAAMDGFE 292 >3I83-A nrPDB Length = 320 Score = 31.2 bits (69), Expect = 1.5, Method: Composition-based stats. Identities = 24/138 (17%), Positives = 53/138 (38%), Gaps = 13/138 (9%) Query: 314 KVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEKF 373 + +IG G +GS L + + V + ++ G R+R ++ F Sbjct: 4 NILVIGTGAIGSFYGALLAKTGHCVSVVSRSDYETVKAKGI-------RIRSATLGDYTF 56 Query: 374 EKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADLEKYCPQHCI-LASNTSTIDL 432 + ++++ + + E+ D ++ V+E + + + P I L SN I+ Sbjct: 57 -RPAAVVRSAAELETKPDCTLLCIKVVEGAD-RVGLLR--DAVAPDTGIVLISNGIDIEP 112 Query: 433 NKIGERTKSQDRIVGAHF 450 ++ + I G F Sbjct: 113 -EVAAAFPDNEVISGLAF 129 >4JCQ-A nrPDB Length = 201 Score = 31.2 bits (69), Expect = 1.5, Method: Composition-based stats. Identities = 21/139 (15%), Positives = 44/139 (31%), Gaps = 31/139 (22%) Query: 84 PKAGYISIDIITDLLEAARKPSVAAI-DGLALGGGLELAMACHARISAPAAQLGLPELQL 142 + D I D+++ KP+V + G G+ + +A + + LP + Sbjct: 60 QGGHVEAGDTIHDMIKFI-KPTVKVVGTGWVASAGITIYLA-----AEKENRFSLPNTRY 113 Query: 143 GVIPGFGGTQ------------------RLPRLVGLTKALEMIL----TSKPV--KAEEG 178 + GG Q R+ RL+ T + E Sbjct: 114 MIHQPAGGVQGQSTEIEIEAKEIIRMRERINRLIAEATGQSYEQISKDTDRNFWLSVNEA 173 Query: 179 HSLGLIDAVVPPAELVTTA 197 G+++ ++ + + A Sbjct: 174 KDYGIVNEIIENRDGLKMA 192 >1ON3-A nrPDB Length = 523 Score = 31.2 bits (69), Expect = 1.7, Method: Composition-based stats. Identities = 34/190 (17%), Positives = 57/190 (30%), Gaps = 32/190 (16%) Query: 56 VITGAKGRF---SGGFDISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGL 112 ++TG F SGG I + G K A ++ P +A I G Sbjct: 127 LLTGTPFLFFYDSGGARIQEGIDSLSGYGKMFFANVKLSGVV---------PQIAIIAGP 177 Query: 113 ALGGGLELAMACHARISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKP 172 GG I A + + G Q + + G +T+ Sbjct: 178 CAGGASYSPALTDFIIMTKKAHMFIT-----------GPQVIKSVTGED------VTADE 220 Query: 173 VKAEEGHSL--GLIDAVVPPAELVTT-ARRWALDIVGRRKPWVSSVSKTDKLPPLGEARE 229 + E H G I V + A++ + S V+ + + P E R+ Sbjct: 221 LGGAEAHMAISGNIHFVAEDDDAAELIAKKLLSFLPQNNTEEASFVNPNNDVSPNTELRD 280 Query: 230 ILTFAKAQTL 239 I+ + Sbjct: 281 IVPIDGKKGY 290 >5KVH-A nrPDB Length = 543 Score = 31.2 bits (69), Expect = 1.7, Method: Composition-based stats. Identities = 21/104 (20%), Positives = 37/104 (35%), Gaps = 11/104 (10%) Query: 297 AKVPGVTDRGLVPRKIKKVAIIGGGLMGSGIATALILS----NYPVILKEVNEKFLEAGI 352 K+ + R++K + IIGGG +GS +A AL VI L Sbjct: 209 RKIGDFRSLEKISREVKSITIIGGGFLGSELACALGRKARALGTEVI-------QLFPEK 261 Query: 353 GRVKANLQSRVRKGSMSQEKFEKTMSLLKGSLDYESFRDVDMVI 396 G + L + +M + + E + + ++I Sbjct: 262 GNMGKILPEYLSNWTMEKVRREGVKVMPNAIVQSVGVSSGKLLI 305 >1C0L-A nrPDB Length = 363 Score = 31.2 bits (69), Expect = 1.7, Method: Composition-based stats. Identities = 10/36 (27%), Positives = 19/36 (52%), Gaps = 2/36 (5%) Query: 313 KKVAIIGGGLMGSGIATALILSNYPV--ILKEVNEK 346 K+V ++G G++G A L Y V + +++ E Sbjct: 7 KRVVVLGSGVIGLSSALILARKGYSVHILARDLPED 42 >4KWB-A nrPDB Length = 273 Score = 31.2 bits (69), Expect = 1.7, Method: Composition-based stats. Identities = 25/126 (19%), Positives = 39/126 (30%), Gaps = 22/126 (17%) Query: 36 LYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGFGEMQKGNVKEPKAGYISIDIIT 95 N E A VK IV+ G + E+ K + K Sbjct: 36 HRTFLKNLERAKDDKTVKGIVLKVNSP----GGGVYESAEIHKKLEEIKKETK------- 84 Query: 96 DLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAAQLGLPELQLGVIPGFGGTQRLP 155 KP ++ +A GG ++ A + P G LGVI +L Sbjct: 85 -------KPIYVSMGSMAASGGYYISTAADKIFATPETLTG----SLGVIMESVNYSKLA 133 Query: 156 RLVGLT 161 +G++ Sbjct: 134 DKLGIS 139 >2EEZ-A nrPDB Length = 369 Score = 31.2 bits (69), Expect = 1.8, Method: Composition-based stats. Identities = 12/36 (33%), Positives = 19/36 (52%) Query: 314 KVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLE 349 V I+GGG +G+ A + V + +VN K L+ Sbjct: 168 SVVILGGGTVGTNAAKIALGMGAQVTILDVNHKRLQ 203 >4RQU-A nrPDB Length = 375 Score = 31.2 bits (69), Expect = 1.9, Method: Composition-based stats. Identities = 15/54 (27%), Positives = 23/54 (42%), Gaps = 1/54 (1%) Query: 301 GVTDRGLVPRKIKKVAIIGGGLMGSGIATALILSNY-PVILKEVNEKFLEAGIG 353 G T P+K + VAI G G +G G A ++ +I + N K + Sbjct: 180 GATLNVAKPKKGQSVAIFGLGAVGLGAAEGARIAGASRIIGVDFNSKRFDQAKE 233 >3NEP-X nrPDB Length = 314 Score = 30.8 bits (68), Expect = 1.9, Method: Composition-based stats. Identities = 8/34 (23%), Positives = 19/34 (55%), Gaps = 2/34 (5%) Query: 314 KVAIIGGGLMGSGIATALILSNY--PVILKEVNE 345 KV +IG G +G+ +A + + V++ ++ + Sbjct: 2 KVTVIGAGNVGATVAECVARQDVAKEVVMVDIKD 35 >3H2Z-A nrPDB Length = 382 Score = 30.8 bits (68), Expect = 2.0, Method: Composition-based stats. Identities = 18/83 (21%), Positives = 31/83 (37%), Gaps = 4/83 (4%) Query: 319 GGGLMGSG-IATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEKFEKTM 377 G G +G G I L + + +VN+ L+A + + Q V + + Sbjct: 7 GAGNIGRGFIGKLLADAGIQLTFADVNQVVLDAL--NARHSYQVHVVGETEQVDTVSGVN 64 Query: 378 SLLKGSLDYESF-RDVDMVIEAV 399 ++ D VD+V AV Sbjct: 65 AVSSIGDDVVDLIAQVDLVTTAV 87 >2RIR-A nrPDB Length = 300 Score = 30.8 bits (68), Expect = 2.1, Method: Composition-based stats. Identities = 14/89 (15%), Positives = 26/89 (29%), Gaps = 9/89 (10%) Query: 271 AEVASQVVKLDTTKGLIHVFFSQRGTAKVPGVTDRGLVPRKIKK---------VAIIGGG 321 + + + + L+ +F T G + I+ VA++G G Sbjct: 107 SNAYLENIAAQAKRKLVKLFERDDIAIYNSIPTVEGTIMLAIQHTDYTIHGSQVAVLGLG 166 Query: 322 LMGSGIATALILSNYPVILKEVNEKFLEA 350 G IA V + + L Sbjct: 167 RTGMTIARTFAALGANVKVGARSSAHLAR 195 >3AEO-A nrPDB Length = 389 Score = 30.8 bits (68), Expect = 2.1, Method: Composition-based stats. Identities = 15/75 (20%), Positives = 29/75 (38%) Query: 342 EVNEKFLEAGIGRVKANLQSRVRKGSMSQEKFEKTMSLLKGSLDYESFRDVDMVIEAVIE 401 ++ +K + ++S + + T+++ G +D M AV E Sbjct: 294 DIAKKQMTGYGSTFLFEMKSFEAAKKLMEHLKVCTLAVSLGCVDTLIEHPASMTHAAVPE 353 Query: 402 NISLKQQIFADLEKY 416 NI KQ I +L + Sbjct: 354 NIMRKQGITPELVRI 368 >3RST-A nrPDB Length = 240 Score = 30.8 bits (68), Expect = 2.1, Method: Composition-based stats. Identities = 25/126 (19%), Positives = 39/126 (30%), Gaps = 22/126 (17%) Query: 36 LYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGFGEMQKGNVKEPKAGYISIDIIT 95 N E A VK IV+ G + E+ K + K Sbjct: 31 HRTFLKNLERAKDDKTVKGIVLKVNSP----GGGVYESAEIHKKLEEIKKETK------- 79 Query: 96 DLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAAQLGLPELQLGVIPGFGGTQRLP 155 KP ++ +A GG ++ A + P G LGVI +L Sbjct: 80 -------KPIYVSMGSMAASGGYYISTAADKIFATPETLTG----SLGVIMESVNYSKLA 128 Query: 156 RLVGLT 161 +G++ Sbjct: 129 DKLGIS 134 >2W8Z-A nrPDB Length = 470 Score = 30.8 bits (68), Expect = 2.2, Method: Composition-based stats. Identities = 19/120 (15%), Positives = 46/120 (38%), Gaps = 24/120 (20%) Query: 314 KVAIIGGGLMGSGIATALILSNYPVILK----EVNEKFLEAGIGR-------VKANLQSR 362 ++ +IG +MG +A + Y V + E ++FL+ G+ ++ + + Sbjct: 6 QIGVIGLAVMGKNLALNIESKGYSVAVYNRLREKTDEFLQEAKGKNIVGTYSIEEFVNAL 65 Query: 363 VRKGSM-----SQEKFEKTMSLLKGSLDYESFRDVDMVIE---AVIENISLKQQIFADLE 414 + + + + T+ LK D+VI+ ++ + + A+L Sbjct: 66 EKPRKILLMVKAGAPTDATIEQLKP-----HLEKGDIVIDGGNTYFKDTQRRNKELAELG 120 >2LDB-A nrPDB Length = 317 Score = 30.8 bits (68), Expect = 2.2, Method: Composition-based stats. Identities = 22/115 (19%), Positives = 39/115 (33%), Gaps = 20/115 (17%) Query: 314 KVAIIGGGLMGSGIATALILSNY--PVILKEVNE-KFLEAGIGRVKANLQSRVRKGSMSQ 370 +V +IG G +G+ AL+ ++L + NE K + + + Sbjct: 8 RVVVIGAGFVGASYVFALMNQGIADEIVLIDANESKAIGDAMDF--------------NH 53 Query: 371 EKFEKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADLEKYCPQHCILAS 425 K + DY+ RD D+V+ N + L+ I S Sbjct: 54 GKVFAPKPVDIWHGDYDDCRDADLVVICAGANQKPGE---TRLDLVDKNIAIFRS 105 >3K30-A nrPDB Length = 690 Score = 30.8 bits (68), Expect = 2.2, Method: Composition-based stats. Identities = 24/134 (17%), Positives = 45/134 (33%), Gaps = 8/134 (5%) Query: 314 KVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEKF 373 +V ++G G G A AL + Y V+L E G ++ L G + + + Sbjct: 393 RVLVVGAGPSGLEAARALGVRGYDVVLAEAGRDL--GGRVTQESALPGLSAWGRVKEYRE 450 Query: 374 EKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADLEKYCPQHCILASNTSTIDLN 433 L + ES D ++E E++ + H T+ + + Sbjct: 451 AVLAELPNVEIYRESPMTGDDIVEFGFEHVITATGATWRTDGVARFH------TTALPIA 504 Query: 434 KIGERTKSQDRIVG 447 + + D G Sbjct: 505 EGMQVLGPDDLFAG 518 >4RPJ-A nrPDB Length = 399 Score = 30.8 bits (68), Expect = 2.3, Method: Composition-based stats. Identities = 23/129 (17%), Positives = 49/129 (37%), Gaps = 13/129 (10%) Query: 531 MPMGPFR---LCDLVGFGVAIATATQFIENFSERTYKSMIIPLMQEDKRAGEATRKGFYL 587 +P+G F+ + + V +F ER Y++ +M+E R E + +Y Sbjct: 270 LPIGDFQGTAVMNYNDLDVPYTRIHEFRHFHPERDYRTDKTVIMREYSRFAEDDDEPYYP 329 Query: 588 YDDK----------RKAKPDPELKKYIEKARSISGVKLDPKLANLSEKDIIEMTFFPVVN 637 + + +AK + K + R + LD +A S ++ + P + Sbjct: 330 INTEADRALLATYRARAKSETASSKVLFGGRLGTYQYLDMHMAIASALNMYDNVLAPHLR 389 Query: 638 EACRVFAEG 646 + + +G Sbjct: 390 DGVPLLQDG 398 >1X54-A nrPDB Length = 434 Score = 30.8 bits (68), Expect = 2.4, Method: Composition-based stats. Identities = 13/70 (18%), Positives = 23/70 (32%), Gaps = 3/70 (4%) Query: 180 SLGLIDAVVPPAELVTTARRWALDIVGRRKPWVSSVSKTDKLPPLGEAREILTFAKAQTL 239 S G++ AVV + A + V + K D+ P G + K + + Sbjct: 42 STGIVQAVVAKNVVGEETFEKAKKLGRESSVIVEGIVKADERAPGGAEVHV---EKLEVI 98 Query: 240 KRAPNMKHPL 249 + P Sbjct: 99 QAVSEFPIPE 108 >4DGK-A nrPDB Length = 501 Score = 30.4 bits (67), Expect = 2.6, Method: Composition-based stats. Identities = 12/35 (34%), Positives = 18/35 (51%) Query: 312 IKKVAIIGGGLMGSGIATALILSNYPVILKEVNEK 346 +K +IG G G +A L + PV+L E +K Sbjct: 1 MKPTTVIGAGFGGLALAIRLQAAGIPVLLLEQRDK 35 >2PA3-A nrPDB Length = 410 Score = 30.4 bits (67), Expect = 2.6, Method: Composition-based stats. Identities = 24/131 (18%), Positives = 40/131 (30%), Gaps = 29/131 (22%) Query: 313 KKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEK 372 KK+ IIG G +G+ + V ++ K + Sbjct: 152 KKLGIIGYGHIGTQLGILAESLGMYVYFYDIE-------------------NKLPLGNAT 192 Query: 373 FEKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADLEKYCPQHCIL--ASNTSTI 430 + +S L D S V EN S K + A +L AS + + Sbjct: 193 QVQHLSDLLNMSDVVSLH--------VPENPSTKNMMGAKEISLMKPGSLLINASRGTVV 244 Query: 431 DLNKIGERTKS 441 D+ + + S Sbjct: 245 DIPALADALAS 255 >2EER-A nrPDB Length = 347 Score = 30.4 bits (67), Expect = 2.7, Method: Composition-based stats. Identities = 14/46 (30%), Positives = 20/46 (43%), Gaps = 6/46 (13%) Query: 311 KIKKVAIIGGG----LMGSGIATALILSNYPVILKEVNEKFLEAGI 352 K + +IG G M IA +S +I +V E+ LEA Sbjct: 170 PSKTLVVIGAGGGLGTMAIQIAK--AVSGATIIGVDVREEALEAAK 213 >1ZOV-A nrPDB Length = 386 Score = 30.4 bits (67), Expect = 2.8, Method: Composition-based stats. Identities = 7/28 (25%), Positives = 11/28 (39%) Query: 315 VAIIGGGLMGSGIATALILSNYPVILKE 342 V ++G G MG L +L + Sbjct: 6 VIVVGAGSMGMAAGYYLAKQGVKTLLVD 33 >1PZF-A nrPDB Length = 331 Score = 30.1 bits (66), Expect = 3.2, Method: Composition-based stats. Identities = 12/32 (37%), Positives = 18/32 (56%), Gaps = 1/32 (3%) Query: 313 KKVAIIGGGLMGSGIATALILSNYP-VILKEV 343 KKVA+IG G++G + L V+L +V Sbjct: 10 KKVAMIGSGMIGGTMGYLCALRELADVVLYDV 41 >6APH-A nrPDB Length = 445 Score = 30.1 bits (66), Expect = 3.3, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 22/45 (48%), Gaps = 1/45 (2%) Query: 313 KKVAIIGGGLMGSGIATALILSNYPVILKEVNEK-FLEAGIGRVK 356 K+V + G G +G G A + + V + E++ L+A + + Sbjct: 227 KRVVVCGFGDVGKGTAASFRGAGSIVTVTEIDPICALQAAMEGYE 271 >5A9T-A nrPDB Length = 290 Score = 30.1 bits (66), Expect = 3.4, Method: Composition-based stats. Identities = 10/31 (32%), Positives = 16/31 (51%) Query: 315 VAIIGGGLMGSGIATALILSNYPVILKEVNE 345 V + G G MGS +A AL+ + V + + Sbjct: 8 VTVAGLGPMGSALAAALLDRGHDVTVWNRSP 38 >2DFV-A nrPDB Length = 347 Score = 30.1 bits (66), Expect = 3.5, Method: Composition-based stats. Identities = 16/42 (38%), Positives = 20/42 (47%), Gaps = 1/42 (2%) Query: 313 KKVAIIGGGLMGS-GIATALILSNYPVILKEVNEKFLEAGIG 353 K V I G G +G GIA A YPVI+ E ++ E Sbjct: 168 KSVLITGAGPLGLLGIAVAKASGAYPVIVSEPSDFRRELAKK 209 >1GQY-A nrPDB Length = 475 Score = 30.1 bits (66), Expect = 3.5, Method: Composition-based stats. Identities = 14/73 (19%), Positives = 31/73 (42%), Gaps = 1/73 (1%) Query: 310 RKIKKVAIIGGGLMG-SGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSM 368 R+++++ IG G G SGIA L+ Y + ++ + + + + A + + + Sbjct: 16 RRVQQIHFIGIGGAGMSGIAEILLNEGYQISGSDIADGVVTQRLAQAGAKIYIGHAEEHI 75 Query: 369 SQEKFEKTMSLLK 381 S +K Sbjct: 76 EGASVVVVSSAIK 88 >3ABT-A nrPDB Length = 662 Score = 30.1 bits (66), Expect = 3.6, Method: Composition-based stats. Identities = 14/42 (33%), Positives = 19/42 (45%) Query: 305 RGLVPRKIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEK 346 + L +K KV IIG G+ G A L V L E ++ Sbjct: 100 KPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDR 141 >1CF2-P nrPDB Length = 337 Score = 30.1 bits (66), Expect = 3.6, Method: Composition-based stats. Identities = 21/102 (20%), Positives = 43/102 (42%), Gaps = 3/102 (2%) Query: 312 IKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQE 371 +K VAI G G +G +A A+ + + + V++ + + Sbjct: 1 MKAVAINGYGTVGKRVADAIAQQD-DMKVIGVSKTRPDFEARMALKKGYDLYVAIPERVK 59 Query: 372 KFEKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQ-QIFAD 412 FEK + G++D + + D+VI+ E I K +++ + Sbjct: 60 LFEKAGIEVAGTVD-DMLDEADIVIDCTPEGIGAKNLKMYKE 100 >2P4Q-A nrPDB Length = 497 Score = 30.1 bits (66), Expect = 3.7, Method: Composition-based stats. Identities = 9/66 (13%), Positives = 21/66 (31%), Gaps = 3/66 (4%) Query: 316 AIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEKFEK 375 +IG +MG + + V + ++ + + G+ S E F Sbjct: 14 GLIGLAVMGQNLILNAADHGFTVCAYNRTQSKVDHFLANEAKG---KSIIGATSIEDFIS 70 Query: 376 TMSLLK 381 + + Sbjct: 71 KLKRPR 76 >3B40-A nrPDB Length = 417 Score = 30.1 bits (66), Expect = 3.8, Method: Composition-based stats. Identities = 18/95 (18%), Positives = 35/95 (36%), Gaps = 3/95 (3%) Query: 536 FRLCDLVGFGVAIATATQFIENFSER---TYKSMIIPLMQEDKRAGEATRKGFYLYDDKR 592 F L L G A+ I + E+ Y S + +++E+ +AG Y K+ Sbjct: 289 FDLPPLEGLDYALMPGDPIITIWPEQRFGEYASALYGILEEEPKAGLKELVDAIDYTVKK 348 Query: 593 KAKPDPELKKYIEKARSISGVKLDPKLANLSEKDI 627 + + G K ++ N++ + I Sbjct: 349 VGIDHVGISSDFNDGGGVDGWKDVSEIRNVTAELI 383 >1BG6-A nrPDB Length = 359 Score = 30.1 bits (66), Expect = 3.8, Method: Composition-based stats. Identities = 15/88 (17%), Positives = 33/88 (37%), Gaps = 8/88 (9%) Query: 313 KKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEK 372 K A++G G G A L L V+ +++ + ++ R + G+ + Sbjct: 5 KTYAVLGLGNGGHAFAAYLALKGQSVLAWDIDAQRIKEIQDRGAIIAEGPGLAGTAHPDL 64 Query: 373 FEKTMSLLKGSLDYESFRDVDMVIEAVI 400 + L + +D D+++ V Sbjct: 65 LTSDIGL--------AVKDADVILIVVP 84 >4WEQ-A nrPDB Length = 341 Score = 29.7 bits (65), Expect = 4.2, Method: Composition-based stats. Identities = 18/100 (18%), Positives = 34/100 (34%), Gaps = 7/100 (7%) Query: 295 GTAKVPGVTDRGLVPRKIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGR 354 AK D V I+G G++G A L + VI +++ +E Sbjct: 144 ALAKKHEWRDLSQPEAADVTVGIMGMGVLGQDAARKLAAMGFKVIGWSRSKRVIEGVETY 203 Query: 355 VKANLQSRVRKGSMSQEKFEKTMSLLKGSLDYESFRDVDM 394 A L + + + + + LL + D + + Sbjct: 204 DAAGLDAFL-------GRTDFLVGLLPLTPDTRGIFNAAL 236 >1Z82-A nrPDB Length = 335 Score = 29.7 bits (65), Expect = 4.2, Method: Composition-based stats. Identities = 14/87 (16%), Positives = 35/87 (40%), Gaps = 13/87 (14%) Query: 314 KVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEKF 373 + ++G G G+ A L + VIL ++ ++ + S + Sbjct: 16 RFFVLGAGSWGTVFAQMLHENGEEVILWARRKEIVD-------------LINVSHTSPYV 62 Query: 374 EKTMSLLKGSLDYESFRDVDMVIEAVI 400 E++ ++ + D E + D+++ A+ Sbjct: 63 EESKITVRATNDLEEIKKEDILVIAIP 89 >4XGI-A nrPDB Length = 436 Score = 29.7 bits (65), Expect = 4.3, Method: Composition-based stats. Identities = 26/158 (16%), Positives = 49/158 (31%), Gaps = 12/158 (7%) Query: 287 IHVFFSQRGTAKVPGVTDRGLVPRKIKKVAIIGGGLMGSGIATALILSNYPVILK-EVNE 345 VF AK GV G ++A+ G G +G A + VI + Sbjct: 212 RGVFVVGCEAAKKKGVEIEGA------RIAVQGFGNVGGIAAKLFQEAGAKVIAVQDHTG 265 Query: 346 KFLEAGIGRVKANLQSRVRKGSMSQEKFEKTMSLLKGSLDYESFRDVDMVIEAVIENISL 405 + L R G ++ + + M + + +++I A +EN Sbjct: 266 TIHQPAGVDTAKLLDHVGRTGGVAGFEGAEPMPNDEFWT-----VETEILIPAALENQIT 320 Query: 406 KQQIFADLEKYCPQHCILASNTSTIDLNKIGERTKSQD 443 ++ K + + T+ D+ D Sbjct: 321 EKNASKIRTKIIVEGANGPTTTAADDILSANGVLVIPD 358 >5J7X-A nrPDB Length = 549 Score = 29.7 bits (65), Expect = 4.4, Method: Composition-based stats. Identities = 18/94 (19%), Positives = 28/94 (29%), Gaps = 3/94 (3%) Query: 313 KKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQ-- 370 KKVA+IG G G I L + + KG + Sbjct: 184 KKVAVIGTGSTGIQIFQEWAREAEEAFLFQRTPNLCLPMRQQELHAGYQVKDKGEYADYL 243 Query: 371 EKFEKTMSLLKG-SLDYESFRDVDMVIEAVIENI 403 + T L+ +F + EA E++ Sbjct: 244 AECALTFGGLEYQQTPKNTFDASEEEREAFWEDL 277 >3GVH-A nrPDB Length = 324 Score = 29.7 bits (65), Expect = 4.4, Method: Composition-based stats. Identities = 18/86 (20%), Positives = 36/86 (41%), Gaps = 15/86 (17%) Query: 313 KKVAIIGGGLMGSGIATALILSNY-PVILKEVNEKFLE-AGIGRVKANLQSRVRKGSMSQ 370 K+A+IG G++G +A L V+L ++ E + G+ +++ Sbjct: 8 NKIALIGSGMIGGTLAHLAGLKELGDVVLFDIAEGTPQGKGLDIAESS------------ 55 Query: 371 EKFEKTMSLLKGSLDYESFRDVDMVI 396 + + G+ DY + D+VI Sbjct: 56 -PVDGFDAKFTGANDYAAIEGADVVI 80 >1QO8-A nrPDB Length = 566 Score = 29.7 bits (65), Expect = 4.4, Method: Composition-based stats. Identities = 9/39 (23%), Positives = 16/39 (41%) Query: 307 LVPRKIKKVAIIGGGLMGSGIATALILSNYPVILKEVNE 345 P + +V ++G G G + A + VIL + Sbjct: 116 AGPSETTQVLVVGAGSAGFNASLAAKKAGANVILVDKAP 154 >3PII-A nrPDB Length = 339 Score = 29.7 bits (65), Expect = 4.5, Method: Composition-based stats. Identities = 9/49 (18%), Positives = 17/49 (34%) Query: 305 RGLVPRKIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIG 353 + + + VAI G G G V+ ++ ++ LE Sbjct: 158 KVTGAKPGEWVAIYGIGGFGHVAVQYAKAMGLNVVAVDIGDEKLELAKE 206 >3CKY-A nrPDB Length = 301 Score = 29.7 bits (65), Expect = 4.6, Method: Composition-based stats. Identities = 10/32 (31%), Positives = 15/32 (46%) Query: 314 KVAIIGGGLMGSGIATALILSNYPVILKEVNE 345 K+ IG G MG +A L+ V ++ E Sbjct: 6 KIGFIGLGAMGKPMAINLLKEGVTVYAFDLME 37 >4O6R-A nrPDB Length = 496 Score = 29.7 bits (65), Expect = 4.7, Method: Composition-based stats. Identities = 19/76 (25%), Positives = 29/76 (38%), Gaps = 12/76 (15%) Query: 111 GLALGGGLELAM-------ACHARISAPAAQLGLPELQLGVIPGFGGT--QRLPRLVGLT 161 G AL G + + RI A++G P + ++PG+G T QRL G+ Sbjct: 168 GPALAAGNTVVLKPSEITPLSTLRIVELMAEVGFPAGVVNIVPGYGHTAGQRLAEHPGVG 227 Query: 162 KALEMILTSKPVKAEE 177 K + T Sbjct: 228 K---IAFTGSTATGRR 240 >4FX9-A nrPDB Length = 453 Score = 29.7 bits (65), Expect = 4.9, Method: Composition-based stats. Identities = 26/127 (20%), Positives = 40/127 (31%), Gaps = 2/127 (1%) Query: 252 LDAIEVGIVSGPRAGLEKEAEVASQVVKLDTTKGLIHVFFSQRGTAKVPGVTDRGLVPRK 311 + E G A AS V L VF + + K Sbjct: 93 VRVRENGGEKSYEWDYLVFANGASPQVPAIEGVNLKGVFTADLPPD--ALAIREYMEKYK 150 Query: 312 IKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQE 371 ++ V IIGGG +G +A A V + E+ L + ++ K ++ Sbjct: 151 VENVVIIGGGYIGIEMAEAFAAQGKNVTMIVRGERVLRRSFDKEVTDILEEKLKKHVNLR 210 Query: 372 KFEKTMS 378 E TM Sbjct: 211 LQEITMK 217 >5L3D-A nrPDB Length = 852 Score = 29.7 bits (65), Expect = 5.1, Method: Composition-based stats. Identities = 14/42 (33%), Positives = 19/42 (45%) Query: 305 RGLVPRKIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEK 346 + L +K KV IIG G+ G A L V L E ++ Sbjct: 271 KPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDR 312 >4X2R-A nrPDB Length = 250 Score = 29.7 bits (65), Expect = 5.2, Method: Composition-based stats. Identities = 27/120 (22%), Positives = 43/120 (35%), Gaps = 11/120 (9%) Query: 44 EEALSRNDVKAIVITGAKGRFSGGFDISGFGEMQKGNVKEPKAGYISIDIITDLLEAARK 103 AL A VI + + G D+ G +G KE + ++D + + R+ Sbjct: 106 TAALEDPQWTARVIAEHGEKIAVGLDVRGTTLAARGWTKEGGDLWQTLDRLNEA--GCRR 163 Query: 104 PSVAAI--DGLALGGGLELAMACHARISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLT 161 V + DG G EL +++A + P + G I L RLV Sbjct: 164 YVVTDVTKDGTLTGPNTELL----RQVAARTS---APVVASGGISSLEDIAALARLVPQG 216 >3WTC-A nrPDB Length = 262 Score = 29.7 bits (65), Expect = 5.3, Method: Composition-based stats. Identities = 16/88 (18%), Positives = 34/88 (38%), Gaps = 4/88 (4%) Query: 313 KKVAIIGGGL-MGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQE 371 K A+ G +G IA L VIL +V + L V+A + V +++ + Sbjct: 9 KIAAVTGAAQGIGKAIALRLAKDGADVILLDVKQDTLAETAKEVEALGRRAV---ALTAD 65 Query: 372 KFEKTMSLLKGSLDYESFRDVDMVIEAV 399 + + ++ +D+++ Sbjct: 66 ISNRDQFRSTLADAAKTLGGLDIMVNNA 93 >3ICS-A nrPDB Length = 588 Score = 29.7 bits (65), Expect = 5.3, Method: Composition-based stats. Identities = 10/39 (25%), Positives = 18/39 (46%) Query: 310 RKIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFL 348 +K + +IGGG +G + L V L E+ + + Sbjct: 185 KKPRHATVIGGGFIGVEMVENLRERGIEVTLVEMANQVM 223 >2HQM-A nrPDB Length = 479 Score = 29.7 bits (65), Expect = 5.4, Method: Composition-based stats. Identities = 13/66 (19%), Positives = 23/66 (34%) Query: 313 KKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEK 372 KKV ++G G +G +A L E L ++ + K ++ K Sbjct: 186 KKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHK 245 Query: 373 FEKTMS 378 K + Sbjct: 246 LSKIVK 251 >3N6R-B nrPDB Length = 531 Score = 29.3 bits (64), Expect = 5.8, Method: Composition-based stats. Identities = 32/153 (20%), Positives = 48/153 (31%), Gaps = 17/153 (11%) Query: 78 KGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAAQLGL 137 G +E + A P V I A GG + + H R Sbjct: 387 PGTSQEYGGVIKHGAKLLYAYGEATVPMVTVITRKAYGGAYVVMSSKHLR---ADFNYAW 443 Query: 138 PELQLGVIPGFGGTQRL-------PRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPP 190 P ++ V+ G T+ + P + A + P A E G +D V+ P Sbjct: 444 PTAEVAVMGAKGATEIIHRGDLGDPEKIAQHTADYEERFANPFVASE---RGFVDEVIQP 500 Query: 191 AELVTTARRWALDIVG-RRKPWVSSVSKTDKLP 222 +T +R A R K K D +P Sbjct: 501 ---RSTRKRVARAFASLRNKSVQMPWKKHDNIP 530 >3VPX-A nrPDB Length = 364 Score = 29.3 bits (64), Expect = 6.1, Method: Composition-based stats. Identities = 13/71 (18%), Positives = 28/71 (39%), Gaps = 4/71 (5%) Query: 288 HVFFSQRGTAKVPGVTDRGLVPRKIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKF 347 +++ + AK D K VA+ G G + + L +I+ ++NE+ Sbjct: 153 GIYYGMKAAAKEAFGDDSLAG----KTVAVQGVGNVAYALCEYLHEEGAKLIITDINEEA 208 Query: 348 LEAGIGRVKAN 358 ++ + A Sbjct: 209 VQRAVDAFGAT 219 >2E3D-A nrPDB Length = 302 Score = 29.3 bits (64), Expect = 6.3, Method: Composition-based stats. Identities = 21/152 (13%), Positives = 54/152 (35%), Gaps = 12/152 (7%) Query: 334 SNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEKFEKTMSLLKGSLDYESFRDVD 393 + + + + + V L V ++ E + E+ D Sbjct: 16 AGLGTRMLPATKAIPKEMLPLVDKPLIQYVVNECIAAGITEIVLVTHSSKNSIENHFDTS 75 Query: 394 MVIEAVIENISLKQQIFADLEKYCPQHCILASNTSTIDLNKIGERTKSQDRIVGAHFF-- 451 +EA++E +K+Q+ +++ CP H T + + ++ AH Sbjct: 76 FELEAMLEK-RVKRQLLDEVQSICPPHV-----TIMQVRQGLAKGLGHA--VLCAHPVVG 127 Query: 452 -SPAHIMPLLEIVRTNHTSAQVIVDLLDVGKK 482 P ++ L +++ + S +L ++ ++ Sbjct: 128 DEPVAVI-LPDVILDEYESDLSQDNLAEMIRR 158 >3IHG-A nrPDB Length = 535 Score = 29.3 bits (64), Expect = 6.9, Method: Composition-based stats. Identities = 9/31 (29%), Positives = 13/31 (41%) Query: 315 VAIIGGGLMGSGIATALILSNYPVILKEVNE 345 V ++G GL G A L V++ E Sbjct: 8 VLVVGAGLGGLSTAMFLARQGVRVLVVERRP 38 >4D3S-A nrPDB Length = 293 Score = 29.3 bits (64), Expect = 7.0, Method: Composition-based stats. Identities = 13/40 (32%), Positives = 20/40 (50%) Query: 315 VAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGR 354 V +IG G MG +A AL+ + Y + + + EA R Sbjct: 11 VTLIGLGPMGQAMAGALLEAGYELTVWNRTKAKAEALAER 50 >4YWE-A nrPDB Length = 487 Score = 28.9 bits (63), Expect = 7.3, Method: Composition-based stats. Identities = 27/137 (19%), Positives = 42/137 (30%), Gaps = 18/137 (13%) Query: 64 FSGGFDISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMA 123 F G GE +T + P I G ++G L A Sbjct: 120 FYAGAADKLHGETLPYQAGYTVLTVREPHGVTGHIVPWNYP--MQIFGRSVGAALAAGNA 177 Query: 124 C------H-----ARISAPAAQLGLPELQLGVIPGFG--GTQRLPRLVGLTKALEMILTS 170 C R++ AA+ GLP L ++ G+G L R G+ + T Sbjct: 178 CVVKPAEDACLSVLRVAELAAEAGLPAGALNIVTGYGHEAGAALARHPGID---HISFTG 234 Query: 171 KPVKAEEGHSLGLIDAV 187 P + + + V Sbjct: 235 SPATGKLVTQMAAENHV 251 >2ZYA-A nrPDB Length = 480 Score = 28.9 bits (63), Expect = 7.5, Method: Composition-based stats. Identities = 8/42 (19%), Positives = 19/42 (45%) Query: 313 KKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGR 354 +++ ++G +MG +A + Y V + + + E I Sbjct: 16 QQIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVIAE 57 >3ETH-A nrPDB Length = 355 Score = 28.9 bits (63), Expect = 8.9, Method: Composition-based stats. Identities = 8/52 (15%), Positives = 20/52 (38%), Gaps = 2/52 (3%) Query: 312 IKKVAIIGGGLMGSGIATALILSNYPV--ILKEVNEKFLEAGIGRVKANLQS 361 +K+V ++G G +G + A V + + + + A ++ Sbjct: 1 MKQVCVLGNGQLGRMLRQAGEPLGIAVWPVGLDAEPAAVPFQQSVITAEIER 52 >5VVW-A nrPDB Length = 315 Score = 28.5 bits (62), Expect = 9.4, Method: Composition-based stats. Identities = 19/137 (13%), Positives = 44/137 (32%), Gaps = 12/137 (8%) Query: 315 VAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEKFE 374 V I G G+ G IA L+ Y V ++ + + + A + + + Sbjct: 14 VGIGGAGMCG--IAEVLLNLGYEVSGSDLKASAVTERLEKFGAQIFIGHQAENADGADVL 71 Query: 375 KTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADL----EKYCPQHCILASNTSTI 430 S + + E ++ I V + ++ A+L + T+++ Sbjct: 72 VVSSAIN-RANPEVASALERRIPVVP-----RAEMLAELMRYRHGIAVAGTHGKTTTTSL 125 Query: 431 DLNKIGERTKSQDRIVG 447 + ++G Sbjct: 126 IASVFAAGGLDPTFVIG 142 >4ROS-A nrPDB Length = 320 Score = 28.5 bits (62), Expect = 9.8, Method: Composition-based stats. Identities = 18/85 (21%), Positives = 31/85 (36%), Gaps = 13/85 (15%) Query: 313 KKVAIIGGGLMGSGIATALILSNY-PVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQE 371 K+A+IG G +G +A L V+L ++ + G A Sbjct: 4 SKIALIGAGQIGGTLAHLAGLKELGDVVLFDI-VDGVPQGKALDIAE-----------SA 51 Query: 372 KFEKTMSLLKGSLDYESFRDVDMVI 396 + + G+ DY + D+VI Sbjct: 52 PVDGFDAKYSGASDYSAIAGADVVI 76 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.132 0.334 Lambda K H 0.267 0.0400 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 24,501,311 Number of Sequences: 36641 Number of extensions: 943313 Number of successful extensions: 4304 Number of sequences better than 10.0: 289 Number of HSP's better than 10.0 without gapping: 256 Number of HSP's successfully gapped in prelim test: 123 Number of HSP's that attempted gapping in prelim test: 3722 Number of HSP's gapped (non-prelim): 427 length of query: 725 length of database: 10,336,785 effective HSP length: 104 effective length of query: 621 effective length of database: 6,526,121 effective search space: 4052721141 effective search space used: 4052721141 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 63 (28.9 bits)