BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9Z2W9 (888 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5IDF-B nrPDB 1793 0.0 4U1Y-A nrPDB 1259 0.0 6QKC-A nrPDB 1231 0.0 5KUF-A nrPDB 631 0.0 5KUH-A nrPDB 295 4e-80 3DP4-A nrPDB 295 6e-80 3FAT-A nrPDB 289 4e-78 5O9A-A nrPDB 274 1e-73 5FXI-A nrPDB 218 9e-57 5UN1-G nrPDB 217 2e-56 5UOW-A nrPDB 214 2e-55 6IRA-D nrPDB 194 1e-49 5UN1-B nrPDB 191 2e-48 5IPR-B nrPDB 186 5e-47 5UP2-B nrPDB 180 3e-45 4PE5-B nrPDB 179 5e-45 5EHM-A nrPDB 170 3e-42 5DT6-A nrPDB 169 6e-42 1YAE-A nrPDB 166 4e-41 5L2E-A nrPDB 164 1e-40 5IKB-A nrPDB 152 5e-37 4MF3-A nrPDB 147 3e-35 2XXT-A nrPDB 145 8e-35 4IGR-A nrPDB 143 4e-34 4WXJ-A nrPDB 103 2e-22 5I2K-B nrPDB 86 6e-17 5CC2-A nrPDB 85 1e-16 5H8N-A nrPDB 84 4e-16 3OEK-A nrPDB 80 3e-15 2RCB-A nrPDB 80 4e-15 2RC9-A nrPDB 78 2e-14 4YKP-A nrPDB 67 4e-11 5TUJ-C nrPDB 57 4e-08 4ZDM-A nrPDB 49 8e-06 4F3S-A nrPDB 48 1e-05 4ZV2-A nrPDB 46 6e-05 4IO3-A nrPDB 46 6e-05 3K4U-A nrPDB 46 8e-05 4PSH-A nrPDB 46 9e-05 5JOS-A nrPDB 44 2e-04 1GGG-A nrPDB 42 0.001 5OTA-A nrPDB 41 0.003 4F3P-A nrPDB 40 0.004 2PYY-A nrPDB 40 0.005 4H5F-A nrPDB 39 0.008 6FXG-A nrPDB 39 0.011 4KPT-A nrPDB 39 0.014 4ZEF-A nrPDB 37 0.028 4KQP-A nrPDB 36 0.065 5ORE-A nrPDB 36 0.093 2Q2A-A nrPDB 35 0.15 2IEE-A nrPDB 35 0.17 4YMX-A nrPDB 35 0.18 3I6V-A nrPDB 35 0.19 4I62-A nrPDB 34 0.22 4FGU-A nrPDB 34 0.25 3TQL-A nrPDB 33 0.67 5EYF-A nrPDB 32 0.97 5HPQ-A nrPDB 31 2.2 5OCH-A nrPDB 31 2.7 6GI9-A nrPDB 30 3.1 6JEQ-A nrPDB 30 3.4 5VXG-A nrPDB 30 3.6 5LOM-A nrPDB 30 3.6 4G4P-A nrPDB 30 5.2 5GZU-A nrPDB 29 8.8 4MS4-A nrPDB 29 9.2 >5IDF-B nrPDB Length = 874 Score = 1793 bits (4645), Expect = 0.0, Method: Compositional matrix adjust. Identities = 858/865 (99%), Positives = 861/865 (99%) Query: 24 FPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFSVTNA 83 FPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFSVTNA Sbjct: 10 FPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFSVTNA 69 Query: 84 FCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSFPTDADVQFVIQMRPALKGAI 143 FCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSFPTDADVQFVIQMRPALKGAI Sbjct: 70 FCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSFPTDADVQFVIQMRPALKGAI 129 Query: 144 LSLLGYYKWEKFVYLYDTERGFSILQAIMEAAVQNNWQVTARSVGNIKDIQEFRRIIEEM 203 LSLL YYKWEKFVYLYDTERGFS+LQAIMEAAVQNNWQVTARSVGNIKD+QEFRRIIEEM Sbjct: 130 LSLLSYYKWEKFVYLYDTERGFSVLQAIMEAAVQNNWQVTARSVGNIKDVQEFRRIIEEM 189 Query: 204 DRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANLGFTDIVLERVMHGGANITG 263 DRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANLGFTDI+LERVMHGGANITG Sbjct: 190 DRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANLGFTDILLERVMHGGANITG 249 Query: 264 FQIVNNENPMVQQFIQRWVRLDEREFPEAKNAPLKYTSALTHDAILVIAEAFRYLRRQRV 323 FQIVNNENPMVQQFIQRWVRLDE EFPEAKNAPLKYTSALTHDAILVIAEAFRYLRRQRV Sbjct: 250 FQIVNNENPMVQQFIQRWVRLDECEFPEAKNAPLKYTSALTHDAILVIAEAFRYLRRQRV 309 Query: 324 DVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNIQFDTYGRRTNYTIDVYEMK 383 DVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNIQFDTYGRRTNYTIDVYEMK Sbjct: 310 DVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNIQFDTYGRRTNYTIDVYEMK 369 Query: 384 VSGSRKAGYWNEYERFVPFSDQQISNDSSSSENRTIVVTTILESPYVMYKKNHEQLEGNE 443 VSGSRKAGYWNEYERFVPFSDQQISNDSSSSENRTIVVTTILESPYVMYKKNHEQLEGNE Sbjct: 370 VSGSRKAGYWNEYERFVPFSDQQISNDSSSSENRTIVVTTILESPYVMYKKNHEQLEGNE 429 Query: 444 RYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPL 503 RYEGYCVDLAYEIAKHV IKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPL Sbjct: 430 RYEGYCVDLAYEIAKHVGIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPL 489 Query: 504 TITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVV 563 TITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVV Sbjct: 490 TITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVV 549 Query: 564 LFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSLGAFMQQGCDISPRSLS 623 LFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSLGAFMQQGCDISPRSLS Sbjct: 550 LFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSLGAFMQQGCDISPRSLS 609 Query: 624 GRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKE 683 GRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKE Sbjct: 610 GRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKE 669 Query: 684 FFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRKP 743 FFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRKP Sbjct: 670 FFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRKP 729 Query: 744 CDTMKVGGNLDSKGYGVATPKGSALRTPVNLAVLKLSEQGILDKLKNKWWYDKGECGAKD 803 CDTMKVGGNLDSKGYGVATPKGSAL TPVNLAVLKLSEQGILDKLKNKWWYDKGECGAKD Sbjct: 730 CDTMKVGGNLDSKGYGVATPKGSALGTPVNLAVLKLSEQGILDKLKNKWWYDKGECGAKD 789 Query: 804 SGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCYKSRAESKRMKLTKNTQNFKPA 863 SGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCYKSRAESKRMKLTKNTQNFKPA Sbjct: 790 SGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCYKSRAESKRMKLTKNTQNFKPA 849 Query: 864 PATNTQNYATYREGYNVYGTESVKI 888 PATNTQNYATYREGYNVYGTESVKI Sbjct: 850 PATNTQNYATYREGYNVYGTESVKI 874 >4U1Y-A nrPDB Length = 819 Score = 1259 bits (3259), Expect = 0.0, Method: Compositional matrix adjust. Identities = 597/830 (71%), Positives = 709/830 (85%), Gaps = 19/830 (2%) Query: 26 NTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFSVTNAFC 85 N+I IGGLF R QE+SAFR + ++T++ F L H+D+L+ +NSF+VTNAFC Sbjct: 1 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSE------FRLTPHIDNLEVANSFAVTNAFC 54 Query: 86 SQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSFPTDADVQFVIQMRPALKGAILS 145 SQFSRGVYAIFGFYD+ S+NT+TSFCG LH SF+TPSFPTD FVIQMRP LKGA+LS Sbjct: 55 SQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLS 114 Query: 146 LLGYYKWEKFVYLYDTERGFSILQAIMEAAVQNNWQVTARSVGNI---KDIQEFRRIIEE 202 L+ YY+W+KF YLYD++RG S LQA++++A + WQVTA +VGNI K + +R + ++ Sbjct: 115 LIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQD 174 Query: 203 MDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANLGFTDIVLERVMHGGANIT 262 ++ ++E+R ++DCE +++N I++QV+ +GKH +GYHY++ANLGFTD L ++ GGA ++ Sbjct: 175 LELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVS 234 Query: 263 GFQIVNNENPMVQQFIQRWVRLDEREFPEAKNAPLKYTSALTHDAILVIAEAFRYLRRQR 322 GFQIV+ ++ +V +FI+RW L+E+E+P A A +KYTSALT+DA+ V+ EAFR LR+QR Sbjct: 235 GFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQR 294 Query: 323 VDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNIQFDTYGRRTNYTIDVYEM 382 +++SRRG+AGDCLANPAVPW QG++IERALK VQV+G++GNI+FD G+R NYTI++ E+ Sbjct: 295 IEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMEL 354 Query: 383 KVSGSRKAGYWNEYERFVPFSDQQISNDSSSSENRTIVVTTILESPYVMYKKNHEQLEGN 442 K +G RK GYW+E ++ V +D+S E +T+VVTTILESPYVM KKNHE LEGN Sbjct: 355 KTNGPRKIGYWSEVDKMVV---TLTEDDTSGLEQKTVVVTTILESPYVMMKKNHEMLEGN 411 Query: 443 ERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAP 502 ERYEGYCVDLA EIAKH KYKL+IVGDGKYGARD +TKIWNGMVGELVYG+ADIA+AP Sbjct: 412 ERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAP 471 Query: 503 LTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSV 562 LTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWM IVFAYI VSV Sbjct: 472 LTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMAIVFAYILVSV 531 Query: 563 VLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSLGAFMQQGCDISPRSL 622 VLFLVSRFSPYEWH EE D + + NEFGIFNS WF+L F QQG DISPRSL Sbjct: 532 VLFLVSRFSPYEWH----TEEFEDGE---ESTNEFGIFNSFWFALKLFFQQGADISPRSL 584 Query: 623 SGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTK 682 S RIV GVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDL+KQTEIAYGTLDSGSTK Sbjct: 585 SARIVAGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTK 644 Query: 683 EFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRK 742 EFFRRSKIAV++KMW+YM+SAEPSVF +TTA+GVARVRKSKGK+A+LLESTMNEYIEQRK Sbjct: 645 EFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRK 704 Query: 743 PCDTMKVGGNLDSKGYGVATPKGSALRTPVNLAVLKLSEQGILDKLKNKWWYDKGECGAK 802 PCDTMKVGGNLDSKGYG+ATPKGS+L TPVNLAVLKLSEQG+LDKLKNKWWYDKGECGAK Sbjct: 705 PCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAK 764 Query: 803 DSGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCYKSRAESKRMK 852 DSGSK+KTSALSLSNVAGVFYILVGGLGLAM+VALIEF YKSRAE+KRMK Sbjct: 765 DSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFAYKSRAEAKRMK 814 >6QKC-A nrPDB Length = 915 Score = 1231 bits (3185), Expect = 0.0, Method: Compositional matrix adjust. Identities = 596/852 (69%), Positives = 698/852 (81%), Gaps = 20/852 (2%) Query: 11 FLVLGLLGHSHGG---------FPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEK 61 F G LG G FPN I IGGLF QEH+AFRFA+ TE Sbjct: 7 FFCTGFLGAVVGADYKDDDDKNFPNNIQIGGLFPNQQSQEHAAFRFALS------QLTEP 60 Query: 62 PFHLNYHVDHLDSSNSFSVTNAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTP 121 P L +D ++ S+SF +T FCSQFS+GVYAIFGFY++ ++N LTSFCGALH F+TP Sbjct: 61 P-KLLPQIDIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITP 119 Query: 122 SFPTDADVQFVIQMRPALKGAILSLLGYYKWEKFVYLYDTERGFSILQAIMEAAVQNNWQ 181 SFP D QFV+Q+RP L+ A++S++ +YKW+ FVY+YD +RG S+LQ +++ A + NWQ Sbjct: 120 SFPVDTSNQFVLQLRPELQEALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQ 179 Query: 182 VTARSVGNIKDIQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYML 241 VTA ++ + + +R + +++++++E+ ++DCE ER+N IL Q+V L K+ GYHY+L Sbjct: 180 VTAVNILTTTE-EGYRMLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYIL 238 Query: 242 ANLGFTDIVLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNAPLKYTS 301 ANLGF DI L + GAN+TGFQ+VN + + + +Q+W D R+ KYTS Sbjct: 239 ANLGFMDIDLNKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDSRDHTRVDWKRPKYTS 298 Query: 302 ALTHDAILVIAEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMT 361 ALT+D + V+AEAF+ LRRQR+D+SRRG+AGDCLANPAVPW QGIDI+RAL+ V+ +G+T Sbjct: 299 ALTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLT 358 Query: 362 GNIQFDTYGRRTNYTIDVYEMKVSGSRKAGYWNEYERFVPF-SDQQISNDSSSSENRTIV 420 GN+QF+ GRRTNYT+ V EMK G RK GYWNE ++FVP +D Q D+SS +NRT + Sbjct: 359 GNVQFNEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYI 418 Query: 421 VTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPE 480 VTTILE PYVM KKN Q EGN+RYEGYCV+LA EIAKHV Y+L IV DGKYGARDP+ Sbjct: 419 VTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPD 478 Query: 481 TKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFS 540 TK WNGMVGELVYGRAD+AVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFS Sbjct: 479 TKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFS 538 Query: 541 FLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIF 600 FLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWH E+ EE RD Q+ D NEFGIF Sbjct: 539 FLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEF-EEGRD-QTTSDQSNEFGIF 596 Query: 601 NSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIE 660 NSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIE Sbjct: 597 NSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIE 656 Query: 661 SAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVR 720 SAEDLAKQTEIAYGTL++GSTKEFFRRSKIAV+EKMW+YMKSAEPSVF +TT +G+ RVR Sbjct: 657 SAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVR 716 Query: 721 KSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRTPVNLAVLKLS 780 KSKGK+A+LLESTMNEYIEQRKPCDTMKVGGNLDSKGYG+ATPKGSALR PVNLAVLKLS Sbjct: 717 KSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLS 776 Query: 781 EQGILDKLKNKWWYDKGECGAKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEF 840 EQG+LDKLK+KWWYDKGECG+KDSGSKDKTSALSLSNVAGVFYIL+GGLGLAM+VALIEF Sbjct: 777 EQGVLDKLKSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEF 836 Query: 841 CYKSRAESKRMK 852 CYKSR+ESKRMK Sbjct: 837 CYKSRSESKRMK 848 >5KUF-A nrPDB Length = 877 Score = 631 bits (1627), Expect = 0.0, Method: Compositional matrix adjust. Identities = 349/829 (42%), Positives = 503/829 (60%), Gaps = 44/829 (5%) Query: 41 EHSAFRFAVQLYNTNQ----NTTEKPFHLNYHVDHLDSSNSFSVTNAFCSQFSRGVYAIF 96 E AFRFAV N N+ NTT L Y ++ +SF + C Q S GV AIF Sbjct: 22 EELAFRFAVNTINRNRTLLPNTT-----LTYDTQKINLYDSFEASKKACDQLSLGVAAIF 76 Query: 97 GFYDQMSMNTLTSFCGALHTSFVTPSFP---TDADVQFVIQMRP---ALKGAILSLLGYY 150 G S N + S C AL + + +D F + + P +L AIL L+ ++ Sbjct: 77 GPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLYPDFSSLSRAILDLVQFF 136 Query: 151 KWEKFVYLYDTERGFSILQAIMEAAVQNNWQVTARSVGNIKDIQEFRRIIEEMDRRQEKR 210 KW+ +YD G LQ +++A + N ++ R + D ++ + +++EM R +E Sbjct: 137 KWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLKIRQLP--ADTKDAKPLLKEMKRGKEFH 194 Query: 211 YLIDCEVERINTILEQVVILGKHSRGYHYMLANLGFTDIVLERVMHGGANITGFQIVNNE 270 + DC E IL+Q + +G + YHY+ L + +E + G N+TGF+I+N E Sbjct: 195 VIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYSGVNMTGFRILNTE 254 Query: 271 NPMVQQFIQRWV--RLDEREFPEAK--NAPLKYTSALTHDAILVIAEAFRYLRRQRVDVS 326 N V I++W RL P++ + + +AL +DA+ V++ A + + V Sbjct: 255 NTQVSSIIEKWSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVVSVAVQQFPQMTV--- 311 Query: 327 RRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNIQFD-TYGRRTNYTIDVYEMKVS 385 S+ C N PW G +K +G+TG I F+ T G RT++ +DV +K Sbjct: 312 ---SSLQC--NRHKPWRFGTRFMSLIKEAHWEGLTGRITFNKTNGLRTDFDLDVISLKEE 366 Query: 386 GSRKAGYWNEYERFVPFSDQQ--ISNDSSSSENRTIVVTTILESPYVMYKKNHEQLEGNE 443 G K G W+ Q+ +N + S NR+++VTTILE PYV++KK+ + L GN+ Sbjct: 367 GLEKIGTWDPASGLNMTESQKGKPANITDSLSNRSLIVTTILEEPYVLFKKSDKPLYGND 426 Query: 444 RYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPL 503 R+EGYC+DL E++ + Y++ +V DGKYGA+D WNGMV EL+ +AD+AVAPL Sbjct: 427 RFEGYCIDLLRELSTILGFTYEIRLVEDGKYGAQDDVNGQWNGMVRELIDHKADLAVAPL 486 Query: 504 TITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVV 563 TIT VRE+VIDFSKPFM+LGISI+ +KP + PGVFSFL+PL+ +IWM ++ AY+GVSVV Sbjct: 487 TITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLAYLGVSVV 546 Query: 564 LFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSLGAFMQQGCDISPRSLS 623 LF+++RFSPYEW+ N P +P S N F + NS WF +GA MQQG ++ P++LS Sbjct: 547 LFVIARFSPYEWY----NPHPCNPDSDV-VENNFTLLNSFWFGVGALMQQGSELMPKALS 601 Query: 624 GRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKE 683 RIVGG+WWFFTLIIISSYTANLAAFLTVERM SPI+SA+DLAKQT+I YG ++ GST Sbjct: 602 TRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVEDGSTMT 661 Query: 684 FFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRKP 743 FF++SKI+ Y+KMW++M S SV K++ +G+ RV S +A L+EST E++ QR Sbjct: 662 FFKKSKISTYDKMWAFMSSRRQSVLVKSSEEGIQRVLTS--DYALLMESTTIEFVTQRN- 718 Query: 744 CDTMKVGGNLDSKGYGVATPKGSALRTPVNLAVLKLSEQGILDKLKNKWWYDKGECGAKD 803 C+ ++GG +DSKGYGV TP GS R + +A+L+L E+G L +K KWW G C ++ Sbjct: 719 CNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNG-CPEEE 777 Query: 804 SGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCYKSRAESKRMK 852 S + SAL + N+ G+F +L GL L++ VA+ EF YKS+ ++ K Sbjct: 778 S---KEASALGVQNIGGIFIVLAAGLVLSVFVAVGEFLYKSKKNAQLEK 823 >5KUH-A nrPDB Length = 757 Score = 295 bits (756), Expect = 4e-80, Method: Compositional matrix adjust. Identities = 182/507 (35%), Positives = 275/507 (54%), Gaps = 32/507 (6%) Query: 41 EHSAFRFAVQLYNTNQ----NTTEKPFHLNYHVDHLDSSNSFSVTNAFCSQFSRGVYAIF 96 E AFRFAV N N+ NTT L Y ++ +SF + C Q S GV AIF Sbjct: 22 EELAFRFAVNTINRNRTLLPNTT-----LTYDTQKINLYDSFEASKKACDQLSLGVAAIF 76 Query: 97 GFYDQMSMNTLTSFCGALHTSFVTPSFP---TDADVQFVIQMRP---ALKGAILSLLGYY 150 G S N + S C AL + + +D F + + P +L AIL L+ ++ Sbjct: 77 GPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLYPDFSSLSRAILDLVQFF 136 Query: 151 KWEKFVYLYDTERGFSILQAIMEAAVQNNWQVTARSVGNIKDIQEFRRIIEEMDRRQEKR 210 KW+ +YD G LQ +++A + N ++ R + D ++ + +++EM R +E Sbjct: 137 KWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLKIRQLP--ADTKDAKPLLKEMKRGKEFH 194 Query: 211 YLIDCEVERINTILEQVVILGKHSRGYHYMLANLGFTDIVLERVMHGGANITGFQIVNNE 270 + DC E IL+Q + +G + YHY+ L + +E + G N+TGF+I+N E Sbjct: 195 VIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYSGVNMTGFRILNTE 254 Query: 271 NPMVQQFIQRWV--RLDEREFPEAK--NAPLKYTSALTHDAILVIAEAFRYLRRQRVDVS 326 N V I++W RL P++ + + +AL +DA+ V++ A + + V Sbjct: 255 NTQVSSIIEKWSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVVSVAVQQFPQMTV--- 311 Query: 327 RRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNIQFD-TYGRRTNYTIDVYEMKVS 385 S+ C N PW G +K +G+TG I F+ T G RT++ +DV +K Sbjct: 312 ---SSLQC--NRHKPWRFGTRFMSLIKEAHWEGLTGRITFNKTNGLRTDFDLDVISLKEE 366 Query: 386 GSRKAGYWNEYERFVPFSDQQ--ISNDSSSSENRTIVVTTILESPYVMYKKNHEQLEGNE 443 G K G W+ Q+ +N + S NR+++VTTILE PYV++KK+ + L GN+ Sbjct: 367 GLEKIGTWDPASGLNMTESQKGKPANITDSLSNRSLIVTTILEEPYVLFKKSDKPLYGND 426 Query: 444 RYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPL 503 R+EGYC+DL E++ + Y++ +V DGKYGA+D WNGMV EL+ +AD+AVAPL Sbjct: 427 RFEGYCIDLLRELSTILGFTYEIRLVEDGKYGAQDDVNGQWNGMVRELIDHKADLAVAPL 486 Query: 504 TITLVREEVIDFSKPFMSLGISIMIKK 530 TIT VRE+VIDFSKPFM+LGISI+ +K Sbjct: 487 TITYVREKVIDFSKPFMTLGISILYRK 513 Score = 176 bits (445), Expect = 6e-44, Method: Compositional matrix adjust. Identities = 89/199 (44%), Positives = 132/199 (66%), Gaps = 7/199 (3%) Query: 654 RMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTA 713 R +PI+SA+DLAKQT+I YG ++ GST FF++SKI+ Y+KMW++M S SV K++ Sbjct: 512 RKGTPIDSADDLAKQTKIEYGAVEDGSTMTFFKKSKISTYDKMWAFMSSRRQSVLVKSSE 571 Query: 714 DGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRTPVN 773 +G+ RV S +A L+EST E++ QR C+ ++GG +DSKGYGV TP GS R + Sbjct: 572 EGIQRVLTS--DYALLMESTTIEFVTQRN-CNLTQIGGLIDSKGYGVGTPMGSPYRDKIT 628 Query: 774 LAVLKLSEQGILDKLKNKWWYDKGECGAKDSGSKDKTSALSLSNVAGVFYILVGGLGLAM 833 +A+L+L E+G L +K KWW G C ++S + SAL + N+ G+F +L GL L++ Sbjct: 629 IAILQLQEEGKLHMMKEKWWRGNG-CPEEES---KEASALGVQNIGGIFIVLAAGLVLSV 684 Query: 834 MVALIEFCYKSRAESKRMK 852 VA+ EF YKS+ ++ K Sbjct: 685 FVAVGEFLYKSKKNAQLEK 703 >3DP4-A nrPDB Length = 278 Score = 295 bits (755), Expect = 6e-80, Method: Compositional matrix adjust. Identities = 142/144 (98%), Positives = 143/144 (99%) Query: 657 SPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGV 716 +PIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGV Sbjct: 135 TPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGV 194 Query: 717 ARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRTPVNLAV 776 ARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSAL TPVNLAV Sbjct: 195 ARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALGTPVNLAV 254 Query: 777 LKLSEQGILDKLKNKWWYDKGECG 800 LKLSEQGILDKLKNKWWYDKGECG Sbjct: 255 LKLSEQGILDKLKNKWWYDKGECG 278 Score = 250 bits (639), Expect = 2e-66, Method: Compositional matrix adjust. Identities = 122/128 (95%), Positives = 122/128 (95%) Query: 403 SDQQISNDSSSSENRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRI 462 S ISNDSS NRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRI Sbjct: 6 SAMGISNDSSRGANRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRI 65 Query: 463 KYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSL 522 KYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSL Sbjct: 66 KYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSL 125 Query: 523 GISIMIKK 530 GISIMIKK Sbjct: 126 GISIMIKK 133 >3FAT-A nrPDB Length = 260 Score = 289 bits (739), Expect = 4e-78, Method: Compositional matrix adjust. Identities = 136/144 (94%), Positives = 143/144 (99%) Query: 657 SPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGV 716 +PIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMW+YM+SAEPSVFT+TTA+GV Sbjct: 117 TPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGV 176 Query: 717 ARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRTPVNLAV 776 ARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGS+LRTPVNLAV Sbjct: 177 ARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLRTPVNLAV 236 Query: 777 LKLSEQGILDKLKNKWWYDKGECG 800 LKLSE G+LDKLKNKWWYDKGECG Sbjct: 237 LKLSEAGVLDKLKNKWWYDKGECG 260 Score = 209 bits (532), Expect = 4e-54, Method: Compositional matrix adjust. Identities = 97/115 (84%), Positives = 108/115 (93%) Query: 416 NRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYG 475 RT+VVTTI+ESPYVMYKKNHE EGN++YEGYCVDLA EIAKH+ IKYK++IV DGKYG Sbjct: 1 GRTVVVTTIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYG 60 Query: 476 ARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKK 530 ARD +TKIWNGMVGELVYG+A+IA+APLTITLVREEVIDFSKPFMSLGISIMIKK Sbjct: 61 ARDADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKK 115 >5O9A-A nrPDB Length = 264 Score = 274 bits (701), Expect = 1e-73, Method: Compositional matrix adjust. Identities = 127/145 (87%), Positives = 141/145 (97%) Query: 657 SPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGV 716 +PIESAEDL+KQTEIAYGTLDSGSTKEFFRRSKIAV++KMW+YM+SAEPSVF +TTA+GV Sbjct: 119 TPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGV 178 Query: 717 ARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRTPVNLAV 776 ARVRKSKGK+A+LLESTMNEYIEQRKPCDTMKVGGNLDSKGYG+ATPKGS+L VNLAV Sbjct: 179 ARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAV 238 Query: 777 LKLSEQGILDKLKNKWWYDKGECGA 801 LKLSEQG+LDKLKNKWWYDKGECG+ Sbjct: 239 LKLSEQGLLDKLKNKWWYDKGECGS 263 Score = 214 bits (544), Expect = 2e-55, Method: Compositional matrix adjust. Identities = 101/115 (87%), Positives = 107/115 (93%) Query: 416 NRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYG 475 N+T+VVTTILESPYVM KKNHE LEGNERYEGYCVDLA EIAKH KYKL+IVGDGKYG Sbjct: 3 NKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYG 62 Query: 476 ARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKK 530 ARD +TKIWNGMVGELVYG+ADIA+APLTIT VREEVIDFSKPFMSLGISIMIKK Sbjct: 63 ARDADTKIWNGMVGELVYGKADIAIAPLTITYVREEVIDFSKPFMSLGISIMIKK 117 >5FXI-A nrPDB Length = 846 Score = 218 bits (555), Expect = 9e-57, Method: Compositional matrix adjust. Identities = 166/599 (27%), Positives = 290/599 (48%), Gaps = 78/599 (13%) Query: 298 KYTSALTHDAILVIAEAFR-YLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQ 356 K SA DA+ V+A+A L ++ + RG C+ N + W G +R L + Sbjct: 274 KNESAHISDAVGVVAQAVHELLEKENITDPPRG----CVGNTNI-WKTGPLFKRVLMSSK 328 Query: 357 -VQGMTGNIQFDTYGRRTNYTIDVYEMKVSGSRKAGYWNEYERFVPFSDQQISNDSSSSE 415 G+TG ++F+ G R + ++ + G +N +P +D++I +E Sbjct: 329 YADGVTGRVEFNEDGDRKFAQYSIMNLQNRKLVQVGIYNG-THVIP-NDRKIIWPGGETE 386 Query: 416 -------NRTIVVTTILESPYVMYKKN-------------------------HEQLEGNE 443 + + + TI + P+V K ++ G+ Sbjct: 387 KPRGYQMSTRLKIVTIHQEPFVYVKPTMSDGTCKEEFTVNGDPVKKVICTGPNDTSPGSP 446 Query: 444 RYE------GYCVDLAYEIAKHVRIKYKLSIVGDGKYGARD----PETKIWNGMVGELVY 493 R+ G+C+DL ++A+ ++ Y++ +V DGK+G ++ K WNGM+GEL+ Sbjct: 447 RHTVPQCCYGFCIDLLIKLARTMQFTYEVHLVADGKFGTQERVQNSNKKEWNGMMGELLS 506 Query: 494 GRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCI 553 G+AD+ VAPLTI R + I+FSKPF G++I++KK + + + SF+ P +W+ + Sbjct: 507 GQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKK-EIPRSTLDSFMQPFQSTLWLLV 565 Query: 554 VFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSLGAFMQQ 613 + V+V+L+L+ RFSP+ ++ E D + +++WFS G + Sbjct: 566 GLSVHVVAVMLYLLDRFSPFGRFKVNSQSESTD---------ALTLSSAMWFSWGVLLNS 616 Query: 614 GC-DISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQT--- 669 G + +PRS S RI+G VW F +II++SYTANLAAFL ++R I D + Sbjct: 617 GIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPRLRNPSD 676 Query: 670 EIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFL 729 + Y T+ S +FRR M+ +M+ ++ A+ + VR +K AF+ Sbjct: 677 KFIYATVKQSSVDIYFRRQ--VELSTMYRHMEKHN----YESAAEAIQAVRDNK-LHAFI 729 Query: 730 LESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRTPVNLAVLKLSEQGILDKLK 789 +S + E+ E + CD + G G+G+ K S + V+L++LK E G ++ L Sbjct: 730 WDSAVLEF-EASQKCDLVTTGELFFRSGFGIGMRKDSPWKQQVSLSILKSHENGFMEDL- 787 Query: 790 NKWWYDKGECGAKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCYKSRAES 848 +K W EC ++ + + L+ N+AGVF ++ GG+ + + IE YK ++ Sbjct: 788 DKTWVRYQECDSRSNAP----ATLTCENMAGVFMLVAGGIVAGIFLIFIEIAYKRHKDA 842 >5UN1-G nrPDB Length = 451 Score = 217 bits (552), Expect = 2e-56, Method: Compositional matrix adjust. Identities = 137/414 (33%), Positives = 222/414 (53%), Gaps = 39/414 (9%) Query: 447 GYCVDLAYEIAKHVRIKYKLSIVGDGKYGARD----PETKIWNGMVGELVYGRADIAVAP 502 G+CVDL ++A+ + Y++ +V DGK+G ++ WNGM+GEL+ G+AD+ VAP Sbjct: 62 GFCVDLLIKLAREMDFTYEVHLVADGKFGTQERVNNSNAAAWNGMMGELLSGQADMIVAP 121 Query: 503 LTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSV 562 LTI R + I+FSKPF G++I++KK + + + SF+ P +W+ + + V+V Sbjct: 122 LTINNERAQYIEFSKPFKYQGLTILVKK-EIPRSTLDSFMQPFQSTLWLLVGLSVHVVAV 180 Query: 563 VLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSLGAFMQQGC-DISPRS 621 +L+L+ RFSP+ ED + +++WFS + G + +PRS Sbjct: 181 MLYLLDRFSPFG-RFED----------------ALTLSSAMWFSWRVLLNSGLGEGAPRS 223 Query: 622 LSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQT---EIAYGTLDS 678 S RI+G VW F +II++SYTANLAAFL + R I D + + Y T+ Sbjct: 224 FSARILGMVWAGFAMIIVASYTANLAAFLVLRRPEERITGINDPRLRNPSDKFIYATVKQ 283 Query: 679 GSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYI 738 S +FRR M+ +M+ ++ A+ + VR +K AF+ +S + E+ Sbjct: 284 SSVDIYFRRQ--VELSTMYRHMEKHN----YESAAEAIQAVRDNK-LHAFIWDSAVLEF- 335 Query: 739 EQRKPCDTMKVGGNLDSKGYGVATPKGSALRTPVNLAVLKLSEQGILDKLKNKWWYDKGE 798 E + CD + G G+G+ K S + V+L +LK E G +++L +K W E Sbjct: 336 EASQKCDLVTTGELFFRSGFGIGMRKDSPWKQEVSLNILKSHENGFMEEL-DKTWVRYQE 394 Query: 799 CGAKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCYKSRAESKRMK 852 C ++ + + L+ N+AGVF ++ GG+ + + IE YKSRAE+KRMK Sbjct: 395 CDSRSNAP----ATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKSRAEAKRMK 444 >5UOW-A nrPDB Length = 814 Score = 214 bits (544), Expect = 2e-55, Method: Compositional matrix adjust. Identities = 165/590 (27%), Positives = 279/590 (47%), Gaps = 72/590 (12%) Query: 298 KYTSALTHDAILVIAEAFRYL-RRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQ 356 K SA DA+ V+A+A L +++ RG C+ N + W G +R L + Sbjct: 253 KNESAHISDAVAVVAQAIHELFEMEQITDPPRG----CVGNTNI-WKTGPLFKRVLMSSK 307 Query: 357 V-QGMTGNIQFDTYGRR--TNYTI-DVYEMKVS--GSRKAGYWNEYERFVPFSDQQISND 410 G+TG I+F+ G R Y+I ++ K+ G Y + +R + + + Sbjct: 308 YPDGVTGRIEFNEDGDRKFAQYSIMNLQNRKLVQVGIFDGSYIIQNDRKIIWPGGETERP 367 Query: 411 SSSSENRTIVVTTILESPYVMYKKNHEQLEGNERYE------------------------ 446 + + + TI + P+V + E Y Sbjct: 368 QGYQMSTRLKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPDETIPGRPTV 427 Query: 447 -----GYCVDLAYEIAKHVRIKYKLSIVGDGKYGARD----PETKIWNGMVGELVYGRAD 497 G+CVDL ++A+ + Y++ +V DGK+G ++ WNGM+GEL+ G+AD Sbjct: 428 PQCCYGFCVDLLIKLAREMDFTYEVHLVADGKFGTQERVNNSNAAAWNGMMGELLSGQAD 487 Query: 498 IAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAY 557 + VAPLTI R + I+FSKPF G++I++KK + + + SF+ P +W+ + + Sbjct: 488 MIVAPLTINNERAQYIEFSKPFKYQGLTILVKK-EIPRSTLDSFMQPFQSTLWLLVGLSV 546 Query: 558 IGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSLGAFMQQGC-D 616 V+V+L+L+ RFSP+ ++ D + +++WFS + G + Sbjct: 547 HVVAVMLYLLDRFSPFGRFKVNSAAAEED---------ALTLSSAMWFSWRVLLNSGLGE 597 Query: 617 ISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQT---EIAY 673 +PRS S RI+G VW F +II++SYTANLAAFL + R I D + + Y Sbjct: 598 GAPRSFSARILGMVWALFAMIIVASYTANLAAFLVLRRPEERITGINDPRLRNPSDKFIY 657 Query: 674 GTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLEST 733 T+ S +FRR M+ +M+ ++ A+ + VR +K AF+ +S Sbjct: 658 ATVKQSSVDIYFRRQ--VELSTMYRHMEKHN----YESAAEAIQAVRDNK-LHAFIWDSA 710 Query: 734 MNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRTPVNLAVLKLSEQGILDKLKNKWW 793 + E+ E + CD + G G+G+ K S + V+L +LK E G +++L +K W Sbjct: 711 VLEF-EASQDCDLVTTGELFFRSGFGIGMRKDSPWKQEVSLNILKSHENGFMEEL-DKTW 768 Query: 794 YDKGECGAKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCYK 843 EC ++ + + L+ N+AGVFY++ GG+ + + IE YK Sbjct: 769 VRYQECDSRSNAP----ATLTFENMAGVFYLVAGGIVAGIFLIFIEIAYK 814 >6IRA-D nrPDB Length = 853 Score = 194 bits (493), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 155/528 (29%), Positives = 255/528 (48%), Gaps = 86/528 (16%) Query: 365 QFDTYGRRTNYTIDVYEMKVSGSRKAGYWNEYERFVPFSDQQISNDSSSSENRTIVVTTI 424 +++ G+ N+T+ S + W Y+ F +D +N +VT + Sbjct: 371 EWEKVGKWENHTL---------SLRHAVWPRYKSF---------SDCEPDDNHLSIVT-L 411 Query: 425 LESPYVMY---------------------KKNHEQLEG---NERYEGYCVDLAYEIAKHV 460 E+P+V+ K N+ EG + +G+C+D+ ++++ V Sbjct: 412 EEAPFVIVEDIDPLTETCVRNTVPCRKFVKINNSTNEGMNVKKCCKGFCIDILKKLSRTV 471 Query: 461 RIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFM 520 + Y L +V +GK+G + +WNGM+GE+VY RA +AV LTI R EV+DFS PF+ Sbjct: 472 KFTYDLYLVTNGKHGKK--VNNVWNGMIGEVVYQRAVMAVGSLTINEERSEVVDFSVPFV 529 Query: 521 SLGISIMIKKPQKS-KPGVFSFLDPLAYEIW-MCIVFAYIGVSVVLFLVSRFSPYEWHLE 578 GIS+M+ + + P +FL+P + +W M V I ++ +F+ FSP ++ Sbjct: 530 ETGISVMVSRSNGTVSPS--AFLEPFSASVWVMMFVMLLIVSAIAVFVFEYFSPVGYN-- 585 Query: 579 DNNEEPRDPQSPPDPPNEFGIFNSLWFSLGAFMQQGCDI-SPRSLSGRIVGGVWWFFTLI 637 N + + P P F I ++W G + +P+ + +I+ VW FF +I Sbjct: 586 RNLAKGKAPHGP-----SFTIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVI 640 Query: 638 IISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAY------GTLDSGSTKEFFRRSKIA 691 ++SYTANLAAF+ R V + D Q Y GT+ +GST+ R + Sbjct: 641 FLASYTANLAAFMIQRRFVDQVTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNIRNN--- 697 Query: 692 VYEKMWSYMKSAEPSVFTKTTADGV--ARVRKSKGKF-AFLLESTMNEYIEQR-KPCDTM 747 Y M YM TK GV A V GK AF+ ++ + Y R + C + Sbjct: 698 -YPYMHQYM--------TKFNQKGVEDALVSLKTGKLDAFIYDAAVLNYKAGRDEGCKLV 748 Query: 748 KVGGN--LDSKGYGVATPKGSALRTPVNLAVLKLSEQGILDKLKNKWWYDKGECGAKDSG 805 +G + GYG+A KGS + ++LA+L+ G +++L+ W G C + Sbjct: 749 TIGSGYIFATTGYGIALQKGSPWKRQIDLALLQFVGDGEMEELETLWL--TGIC--HNEK 804 Query: 806 SKDKTSALSLSNVAGVFYILVGGLGLAMMVALIE-FCYKSRAESKRMK 852 ++ +S L + N+AGVFY+L + L+++ + E YKSRAE+KRMK Sbjct: 805 NEVMSSQLDIDNMAGVFYMLAAAMALSLITFIWEHLFYKSRAEAKRMK 852 >5UN1-B nrPDB Length = 448 Score = 191 bits (484), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 134/420 (31%), Positives = 217/420 (51%), Gaps = 47/420 (11%) Query: 446 EGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTI 505 +G+C+D+ +IAK V+ Y L +V +GK+G + +WNGM+GE+V RA +AV LTI Sbjct: 56 KGFCIDILKKIAKTVKFTYDLYLVTNGKHGKKI--NGVWNGMIGEVVTKRAYMAVGSLTI 113 Query: 506 TLVREEVIDFSKPFMSLGISIMIKKPQKS-KPGVFSFLDPLAYEIW-MCIVFAYIGVSVV 563 R EV+DFS PF+ GIS+M+ + + P +FL+P + ++W M V I +V Sbjct: 114 NEERSEVVDFSVPFIETGISVMVSRSNGTVSPS--AFLEPFSADVWVMMFVMLLIVSAVA 171 Query: 564 LFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSLGAFMQQGCDI-SPRSL 622 +F+ FSP ++ P F I ++W G + +P+ Sbjct: 172 VFVFEYFSPVGYN------------GP-----SFTIGKAIWLLWGLVFNNSLPVQNPKGT 214 Query: 623 SGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ------TEIAYGTL 676 + +I+ VW FF +I ++SYTANLAAF+ R V + D Q +GT+ Sbjct: 215 TSKIMVSVWAFFAVIFLASYTANLAAFMIQRRYVDQVSGLSDKKFQRPNDFSPAFRFGTV 274 Query: 677 DSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNE 736 +GST+ R + Y +M SYM F + + KS AF+ ++ + Sbjct: 275 PNGSTERNIRNN----YLEMHSYMVK-----FNQRSVQDALLSLKSGKLDAFIYDAAVLN 325 Query: 737 YIEQR-KPCDTMKVGGN--LDSKGYGVATPKGSALRTPVNLAVLKLSEQGILDKLKNKWW 793 Y+ R + C + +G + GYG+A K S + V+LA+L+L G +++L+ W Sbjct: 326 YMAGRDEGCKLVTIGSGKVFATTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEELEALWL 385 Query: 794 YDKGECGAKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIE-FCYKSRAESKRMK 852 G C + ++ +S L + N+AGVFY+L + L+++ ++E YKSRAE+KRMK Sbjct: 386 --TGIC--HNEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIMEHLFYKSRAEAKRMK 441 >5IPR-B nrPDB Length = 825 Score = 186 bits (471), Expect = 5e-47, Method: Compositional matrix adjust. Identities = 209/880 (23%), Positives = 369/880 (41%), Gaps = 142/880 (16%) Query: 33 LFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHL-----------DSSNSFSVT 81 + R Q+H AV L T + K H HL S+ S+ Sbjct: 18 FYSRAYAQKHPNMDIAVILVGTTEEVAIKDVHEKDDFHHLPVTPRVELVTMQESDPKSII 77 Query: 82 NAFCSQFS----RGVY--------AIFGFYDQMSMNTLTSFCGALHTSFVTPSFPTDADV 129 C S +GV AI D +S+ TLT G S + + +A + Sbjct: 78 TRICDLMSDKKVQGVVFGDDTDQEAIAQILDFISVQTLTPILGIHGGSSMIMADKEEASM 137 Query: 130 QFVIQMRPALK---GAILSLLGYYKWEKFVYLYDTERGFSILQAIMEAAVQNN---WQV- 182 F Q P+++ +L+++ Y W F + G+ + + + ++N+ W++ Sbjct: 138 FF--QFGPSIEQQASVMLNIMEEYDWYIFSIVTTYFPGYQDFENKVRSTIENSFVGWELE 195 Query: 183 -TARSVGNIKDIQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYML 241 ++ DI +I ++ + Q L+ C E I E +G G+ +++ Sbjct: 196 EVIHLDMSLDDIDS--KIQNQLKKLQSPVILLYCTKEEATYIFEVAHSVGLTGYGFTWIV 253 Query: 242 ANL--GFTDIVLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNAPLKY 299 +L G TD V + G +++ DE ++ + P Sbjct: 254 PSLVAGDTDTVPDEFPTGLISVS---------------------YDEWDY----DLP--- 285 Query: 300 TSALTHDAILVIAEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQG 359 A D I +I A + + + + S+ + + V + ++R L V +G Sbjct: 286 --ARVRDGIAIITTAASTMLSEHNSIPQSKSSCNNIQESRV--YEAHMLKRYLINVTFEG 341 Query: 360 MTGNIQFDTYGRRTNYTIDVYEMKVSGSRKAGYWNEYERFVPFSDQQISNDSSSSENRTI 419 + D Y I + + R Y + + P D +++ E+ +I Sbjct: 342 RDLSFSEDGYQMHPKLVIILLNQERKWERVGKYKDRSLKMWPVFDLYPNSEEHKDEHLSI 401 Query: 420 VVTTILESPYVMYKK--------------NHEQLEGNERYE-----------GYCVDLAY 454 V T+ E+P+V+ + +Q+ R E G+C+D+ Sbjct: 402 V--TLEEAPFVIVEDVDPLSGTCMRNTVPCRKQIRPENRTEEGGNYIKRCCKGFCIDILK 459 Query: 455 EIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVID 514 +IAK V+ Y L +V +GK+G + +WNGM+GE+V RA +AV LTI R EV+D Sbjct: 460 KIAKTVKFTYDLYLVTNGKHGKKI--NGVWNGMIGEVVTKRAYMAVGSLTINEERSEVVD 517 Query: 515 FSKPFMSLGISIMIKKPQKS-KPGVFSFLDPLAYEIW-MCIVFAYIGVSVVLFLVSRFSP 572 FS PF+ GIS+M+ + + P +FL+P + ++W M V I +V +F+ FSP Sbjct: 518 FSVPFIETGISVMVSRSNGTVSPS--AFLEPFSADVWVMMFVMLLIVSAVAVFVFEYFSP 575 Query: 573 YEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSLGAFMQQGCDI-SPRSLSGRIVGGVW 631 ++ P F I ++W G + +P+ + +I+ VW Sbjct: 576 VGYN------------GP-----SFTIGKAIWLLWGLVFNNSLPVQNPKGTTSKIMVSVW 618 Query: 632 WFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ------TEIAYGTLDSGSTKEFF 685 FF +I ++SYTANLAAF+ R V + D Q +GT+ +GST+ Sbjct: 619 AFFAVIFLASYTANLAAFMIQRRYVDQVSGLSDKKFQRPNDFSPAFRFGTVPNGSTERNI 678 Query: 686 RRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQR-KPC 744 R + Y +M SYM F + + KS AF+ ++ + Y+ R + C Sbjct: 679 RNN----YLEMHSYMVK-----FNQRSVQDALLSLKSGKLDAFIYDAAVLNYMAGRDEGC 729 Query: 745 DTMKVGGN--LDSKGYGVATPKGSALRTPVNLAVLKLSEQGILDKLKNKWWYDKGECGAK 802 + +G + GYG+A K S + V+LA+L+L G +++L+ W G C Sbjct: 730 KLVTIGSGKVFATTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEELEALWL--TGIC--H 785 Query: 803 DSGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCY 842 + ++ +S L + N+AGVFY+L + L+++ ++E + Sbjct: 786 NEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIMEHLF 825 >5UP2-B nrPDB Length = 831 Score = 180 bits (456), Expect = 3e-45, Method: Compositional matrix adjust. Identities = 121/409 (29%), Positives = 208/409 (50%), Gaps = 36/409 (8%) Query: 446 EGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTI 505 +G+C+D+ +++K V+ Y L +V +GK+G + +WNGM+GE+VY RA +AV LTI Sbjct: 445 KGFCIDILKKLSKTVKFTYDLYLVTNGKHGKK--IKNVWNGMIGEVVYKRAVMAVGSLTI 502 Query: 506 TLVREEVIDFSKPFMSLGISIMIKKPQKS-KPGVFSFLDPLAYEIW-MCIVFAYIGVSVV 563 R +DFS PF+ GIS+M+ + + P +FL+P + +W M V + ++ Sbjct: 503 NEERSVAVDFSVPFVETGISVMVSRSAGTVSPS--AFLEPFSASVWVMMFVMLLLVSAMA 560 Query: 564 LFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSLGAFMQQGCDI-SPRSL 622 +F+ FSP ++ N + +DP P F I ++W G + +P+ Sbjct: 561 VFIFEYFSPVGYN--RNLAQGKDPHGP-----SFTIGKAVWLLWGLVFNNSLPVQNPKGT 613 Query: 623 SGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAY------GTL 676 + +I+ +W FF +I ++SYTANLAAF+ R V + D Q Y GT+ Sbjct: 614 TSKIIVSIWAFFAVIFLASYTANLAAFMIQRRFVDQVTGLSDNKFQRPHDYSPPFRFGTV 673 Query: 677 DSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNE 736 GST+ R + Y M YM K D + ++ K AF+ ++ + Sbjct: 674 PQGSTERNIRNN----YPDMHQYMVKFH----QKGVQDALVSLKTGKLD-AFIYDAAVLN 724 Query: 737 YIEQR-KPCDTMKVGGN--LDSKGYGVATPKGSALRTPVNLAVLKLSEQGILDKLKNKWW 793 Y+ R + C + +G + GYG+A KGS + P++LA+L+ G +++L+ W Sbjct: 725 YMAGRDEGCKLVTIGSGYIFATTGYGIALQKGSRWKRPIDLALLQFVGDGEMEELEKLWL 784 Query: 794 YDKGECGAKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCY 842 G C + ++ +S L + N+AGVFY+L + L+++ + E + Sbjct: 785 --TGICHTEK--NEVMSSQLDIDNMAGVFYMLAAAMALSLITFVWEHLF 829 >4PE5-B nrPDB Length = 820 Score = 179 bits (454), Expect = 5e-45, Method: Compositional matrix adjust. Identities = 133/409 (32%), Positives = 208/409 (50%), Gaps = 44/409 (10%) Query: 446 EGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTI 505 +G+C+D+ +I+K V+ Y L +V +GK+G + T WNGM+GE+V RA +AV LTI Sbjct: 426 KGFCIDILKKISKSVKFTYDLYLVTNGKHGKKINGT--WNGMIGEVVMKRAYMAVGSLTI 483 Query: 506 TLVREEVIDFSKPFMSLGISIMIKKPQKS-KPGVFSFLDPLAYEIW-MCIVFAYIGVSVV 563 R EV+DFS PF+ GIS+M+ + + P +FL+P + +W M V I +V Sbjct: 484 NEERSEVVDFSVPFIETGISVMVSRSNGTVSPS--AFLEPFSACVWVMMFVMLLIVSAVA 541 Query: 564 LFLVSRFSP--YEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSLGAFMQQGCDI-SPR 620 +F+ FSP Y L D R+P P F I ++W G + +P+ Sbjct: 542 VFVFEYFSPVGYNRSLADG----REPGGP-----SFTIGKAIWLLWGLVFNNSVPVQNPK 592 Query: 621 SLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ------TEIAYG 674 + +I+ VW FF +I ++SYTANLAAF+ E V + D Q +G Sbjct: 593 GTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEYVDQVSGLSDKKFQRPNDFSPPFRFG 652 Query: 675 TLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTM 734 T+ +GST+ R + Y +M +YM F + D K+ AF+ ++ + Sbjct: 653 TVPNGSTERNIRNN----YAEMHAYMGK-----FNQRGVDDALLSLKTGKLDAFIYDAAV 703 Query: 735 NEYIEQR-KPCDTMKVGGN--LDSKGYGVATPKGSALRTPVNLAVLKLSEQGILDKLKNK 791 Y+ R + C + +G S GYG+A K S + V+LA+L+L G +++L+ Sbjct: 704 LNYMAGRDEGCKLVTIGSGKVFASTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEELEAL 763 Query: 792 WWYDKGECGAKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEF 840 W G C + ++ +S L N+AGVFY+ LG AM ++LI F Sbjct: 764 WL--TGIC--HNEKNEVMSSQLDCDNMAGVFYM----LGAAMALSLITF 804 >5EHM-A nrPDB Length = 268 Score = 170 bits (430), Expect = 3e-42, Method: Compositional matrix adjust. Identities = 84/149 (56%), Positives = 105/149 (70%), Gaps = 4/149 (2%) Query: 654 RMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTA 713 R +PIESAEDLAKQT I YG L GST FFR SKI+ Y++MWS+M+SA PSVFT + Sbjct: 120 RKGTPIESAEDLAKQTRIKYGALKGGSTAAFFRDSKISTYQRMWSFMESARPSVFTASNG 179 Query: 714 DGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRTPVN 773 +GV RV K KG +AFL+EST EY+ +R C+ +VGG LD+K YG+ATP S RT +N Sbjct: 180 EGVERVAKGKGSYAFLMESTSIEYVTERN-CELTQVGGMLDTKSYGIATPPNSPYRTAIN 238 Query: 774 LAVLKLSEQGILDKLKNKWWYDK---GEC 799 +LKL E+G L LK KWW +K G+C Sbjct: 239 SVILKLQEEGKLHILKTKWWKEKRGGGKC 267 Score = 129 bits (325), Expect = 4e-30, Method: Compositional matrix adjust. Identities = 60/120 (50%), Positives = 89/120 (74%) Query: 411 SSSSENRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVG 470 S++ +N+T+VVTTIL +PY M K++ L GN+++EGY VDL +EI+K + YK+ +V Sbjct: 2 SANLKNKTLVVTTILSNPYCMRKESAIPLSGNDQFEGYAVDLIHEISKSLGFNYKIQLVP 61 Query: 471 DGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKK 530 DG YG+ + T WNGM+ EL+ RAD+A+A LTIT RE+ +DF+ PFM+LG+SI+ +K Sbjct: 62 DGSYGSLNKLTGEWNGMIRELLEQRADLAIADLTITFEREQAVDFTTPFMNLGVSILYRK 121 >5DT6-A nrPDB Length = 267 Score = 169 bits (427), Expect = 6e-42, Method: Compositional matrix adjust. Identities = 81/143 (56%), Positives = 104/143 (72%), Gaps = 1/143 (0%) Query: 657 SPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGV 716 +PI++ EDL QT++ YGTL GST EFFRRS+I ++ KMW YM +A T +G+ Sbjct: 125 TPIKTPEDLTMQTDVNYGTLLYGSTWEFFRRSQIGLHNKMWEYM-NANQHHSVHTYDEGI 183 Query: 717 ARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRTPVNLAV 776 RVR+SKGK+A L+ES NEY+ R PCDTMKVG N+D+KG+GVATP GS LR +N AV Sbjct: 184 RRVRQSKGKYALLVESPKNEYVNARPPCDTMKVGRNIDTKGFGVATPIGSPLRKRLNEAV 243 Query: 777 LKLSEQGILDKLKNKWWYDKGEC 799 L L E G L +++NKWW+DK EC Sbjct: 244 LTLKENGELLRIRNKWWFDKTEC 266 Score = 124 bits (311), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 65/122 (53%), Positives = 85/122 (69%), Gaps = 3/122 (2%) Query: 412 SSSENRTIVVTTILESPYVMYKKNH--EQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIV 469 S N T +V+++LE PY+ K+ E L GN+R+EGYC DLA +A + IKY++ +V Sbjct: 2 SYDRNHTYIVSSLLEEPYLSLKQYTYGESLVGNDRFEGYCKDLADMLAAQLGIKYEIRLV 61 Query: 470 GDGKYGARDP-ETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMI 528 DG YGA + W+GMVGEL+ ADIA++ +TIT RE VIDFSKPFM+LGISIMI Sbjct: 62 QDGNYGAENQYAPGGWDGMVGELIRKEADIAISAMTITAERERVIDFSKPFMTLGISIMI 121 Query: 529 KK 530 KK Sbjct: 122 KK 123 >1YAE-A nrPDB Length = 312 Score = 166 bits (420), Expect = 4e-41, Method: Compositional matrix adjust. Identities = 77/136 (56%), Positives = 105/136 (77%) Query: 408 SNDSSSSENRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLS 467 +N + S NR+++VTTILE PYV++KK+ + L GN+R+EGYC+DL E++ + Y++ Sbjct: 4 ANITDSLSNRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIR 63 Query: 468 IVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIM 527 +V DGKYGA+D WNGMV EL+ +AD+AVAPL IT VRE+VIDFSKPFM+LGISI+ Sbjct: 64 LVEDGKYGAQDDVNGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISIL 123 Query: 528 IKKPQKSKPGVFSFLD 543 +KP + PGVFSFL+ Sbjct: 124 YRKPNGTNPGVFSFLN 139 Score = 153 bits (386), Expect = 3e-37, Method: Compositional matrix adjust. Identities = 78/165 (47%), Positives = 111/165 (67%), Gaps = 7/165 (4%) Query: 653 ERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTT 712 ERM SPI+SA+DLAKQT+I YG ++ G+T FF++SKI+ Y+KMW++M S SV K+ Sbjct: 149 ERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSN 208 Query: 713 ADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRTPV 772 +G+ RV S +AFL+EST E++ QR C+ ++GG +DSKGYGV TP GS R + Sbjct: 209 EEGIQRVLTS--DYAFLMESTTIEFVTQRN-CNLTQIGGLIDSKGYGVGTPMGSPYRDKI 265 Query: 773 NLAVLKLSEQGILDKLKNKWWYDKGECGAKDSGSKDKTSALSLSN 817 +A+L+L E+G L +K KWW G C ++S + SAL + N Sbjct: 266 TIAILQLQEEGKLHMMKEKWWRGNG-CPEEES---KEASALGVQN 306 >5L2E-A nrPDB Length = 688 Score = 164 bits (415), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 137/546 (25%), Positives = 252/546 (46%), Gaps = 54/546 (9%) Query: 23 GFPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNT--TEKPFHLNYHVDHLDSSNSFSV 80 G + I IG +F + ++ FR AV N N+ TEK + + V +D +N F Sbjct: 1 GSDSIIHIGAIFDESAKKDDEVFRTAVGDLNQNEEILQTEK---ITFSVTFVDGNNPFQA 57 Query: 81 TNAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFV-----TPSFP--------TDA 127 C ++G+ A+ S +L S A+H + T P ++ Sbjct: 58 VQEACELMNQGILALVSSIGCTSAGSLQSLADAMHIPHLFIQRSTAGTPRSGCGLTRSNR 117 Query: 128 DVQFVIQMRPA--LKGAILSLLGYYKWEKFVYLYDTERGFSILQAIMEAAVQNNWQVTAR 185 + + + +RP L IL ++ Y W+KF+ YD+E +Q ++ Q V + Sbjct: 118 NDDYTLSVRPPVYLNEVILRVVTEYAWQKFIIFYDSEYDIRGIQEFLDKVSQQGMDVALQ 177 Query: 186 SVGN-----IKDIQEFRRIIEEMDRRQE--KRYLIDCEVERINTILEQVVILGKHSRGYH 238 V N I + + RI EE++R ++ +R ++ + + +VV + H Sbjct: 178 KVENNINKMITTLFDTMRI-EELNRYRDTLRRAILVMNPATAKSFISEVVETNLVAFDCH 236 Query: 239 YMLANLGFTDIVLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDER--------EFP 290 +++ N D+ ++ ++ +I I+ P+ Q QR R + R + P Sbjct: 237 WIIINEEINDVDVQELVR--RSIGRLTIIRQTFPVPQNISQRCFRGNHRISSTLCDPKDP 294 Query: 291 EAKNAPLKYTSALTHDAILVIAEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIER 350 A+N ++ ++ +D +L++A AF + R S ++ C+ + PW G + Sbjct: 295 FAQN--MEISNLYIYDTVLLLANAFHKKLQDRKWHSM--ASLSCIRKNSKPWQGGRSMLE 350 Query: 351 ALKMVQVQGMTGNIQFDTYGRRTNYTIDVY-----EMKVSGSRKAGYWNEYERFV-PFSD 404 +K V G+TG+++F G N ++ E G RK G WN +D Sbjct: 351 TIKKGGVNGLTGDLEFGENGGNPNVHFEILGTNYGEELGRGVRKLGCWNPVTGLNGSLTD 410 Query: 405 QQISNDSSSSENRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKY 464 +++ N+ R V T+LE P+VM +N L ++Y+G+ +D+ ++ ++ Y Sbjct: 411 KKLENNMRGVVLR---VVTVLEEPFVMVSEN--VLGKPKKYQGFSIDVLDALSNYLGFNY 465 Query: 465 KLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGI 524 ++ + D KYG+ E WNG+VGELV+ RADI ++ LTIT RE V+DF+ +M + Sbjct: 466 EIYVAPDHKYGSPQ-EDGTWNGLVGELVFKRADIGISALTITPDRENVVDFTTRYMDYSV 524 Query: 525 SIMIKK 530 +++++ Sbjct: 525 GVLLRR 530 Score = 80.9 bits (198), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 47/154 (30%), Positives = 80/154 (51%), Gaps = 10/154 (6%) Query: 654 RMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKI------AVYEKMWSYMKSAEPSV 707 R + I+S +DL+KQT+I YGT+ + + R + ++Y +MW + + S Sbjct: 529 RRGTSIQSLQDLSKQTDIPYGTVLDSAVYQHVRMKGLNPFERDSMYSQMWRMINRSNGS- 587 Query: 708 FTKTTADGVARVRKSK-GKFAFLLESTMNEYIEQRKP-CDTMKVGGNLDSKGYGVATPKG 765 + A ++K K G +AF+ ++ + EY+ P C VG + +GYG+A G Sbjct: 588 -ENNVLESQAGIQKVKYGNYAFVWDAAVLEYVAINDPDCSFYTVGNTVADRGYGIALQHG 646 Query: 766 SALRTPVNLAVLKLSEQGILDKLKNKWWYDKGEC 799 S R + +L+L + G +D LK+KWW G+C Sbjct: 647 SPYRDVFSQRILELQQSGDMDILKHKWWPKNGQC 680 >5IKB-A nrPDB Length = 257 Score = 152 bits (385), Expect = 5e-37, Method: Compositional matrix adjust. Identities = 75/146 (51%), Positives = 100/146 (68%), Gaps = 4/146 (2%) Query: 654 RMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTA 713 R +PIES +DLA QT I YGT+ GS+ FF+ S+ Y++MW+YM S +PSVF K+T Sbjct: 115 RKGTPIESVDDLADQTAIEYGTIHGGSSMTFFQNSRYQTYQRMWNYMYSKQPSVFVKSTE 174 Query: 714 DGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRTPVN 773 +G+ARV S +AFLLESTMNEY QR C+ ++GG LD+KGYG+ P GS R + Sbjct: 175 EGIARVLNS--NYAFLLESTMNEYYRQRN-CNLTQIGGLLDTKGYGIGMPVGSVFRDEFD 231 Query: 774 LAVLKLSEQGILDKLKNKWWYDKGEC 799 LA+L+L E L+ LK KWW + G+C Sbjct: 232 LAILQLQENNRLEILKRKWW-EGGKC 256 Score = 149 bits (377), Expect = 4e-36, Method: Compositional matrix adjust. Identities = 82/162 (50%), Positives = 110/162 (67%), Gaps = 12/162 (7%) Query: 416 NRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYG 475 N T+VVTTILE+PY+M K NH+ +EGN+RYEG+CVD+ E+A+ +R YK+ +VGDG YG Sbjct: 3 NTTLVVTTILENPYLMLKGNHQDMEGNDRYEGFCVDMLKELAEILRFNYKIRLVGDGVYG 62 Query: 476 ARDPETK-IWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKK--PQ 532 PE W GMVGEL+ +AD+AVA LTIT RE+VIDFSKPFM+LGISI+ +K P Sbjct: 63 V--PEANGTWTGMVGELIARKADLAVAGLTITAEREKVIDFSKPFMTLGISILYRKGTPI 120 Query: 533 KSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYE 574 +S +D LA + + + G S+ F SR+ Y+ Sbjct: 121 ES-------VDDLADQTAIEYGTIHGGSSMTFFQNSRYQTYQ 155 >4MF3-A nrPDB Length = 261 Score = 147 bits (370), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 80/162 (49%), Positives = 108/162 (66%), Gaps = 6/162 (3%) Query: 413 SSENRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDG 472 S NRT++VTTILE PYVMY+K+ + L GN+R+EGYC+DL E++ + Y + +V DG Sbjct: 1 SLANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLVPDG 60 Query: 473 KYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQ 532 KYGA++ + + WNGMV EL+ RAD+AVAPLTIT VRE+VIDFSKPFM+LGISI+ +K Sbjct: 61 KYGAQNDKGE-WNGMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKGT 119 Query: 533 KSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYE 574 D LA + + G ++ F S+ S YE Sbjct: 120 P-----IDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYE 156 Score = 140 bits (353), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 67/144 (46%), Positives = 97/144 (67%), Gaps = 3/144 (2%) Query: 654 RMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTA 713 R +PI+SA+DLAKQT+I YG + GST FF++SKI+ YEKMW++M S + + + + Sbjct: 116 RKGTPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQTALVRNSD 175 Query: 714 DGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRTPVN 773 +G+ RV + +A L+EST EY+ QR C+ ++GG +DSKGYGV TP GS R + Sbjct: 176 EGIQRVLTT--DYALLMESTSIEYVTQRN-CNLTQIGGLIDSKGYGVGTPIGSPYRDKIT 232 Query: 774 LAVLKLSEQGILDKLKNKWWYDKG 797 +A+L+L E+G L +K KWW G Sbjct: 233 IAILQLQEEGKLHMMKEKWWRGNG 256 >2XXT-A nrPDB Length = 261 Score = 145 bits (366), Expect = 8e-35, Method: Compositional matrix adjust. Identities = 67/115 (58%), Positives = 91/115 (79%) Query: 416 NRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYG 475 NR+++VTTILE PYV++KK+ + L GN+R+EGYC+DL E++ + Y++ +V DGKYG Sbjct: 3 NRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDGKYG 62 Query: 476 ARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKK 530 A+D WNGMV EL+ +AD+AVAPL IT VRE+VIDFSKPFM+LGISI+ +K Sbjct: 63 AQDDVNGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRK 117 Score = 145 bits (365), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 69/144 (47%), Positives = 99/144 (68%), Gaps = 3/144 (2%) Query: 654 RMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTA 713 R +PI+SA+DLAKQT+I YG ++ G+T FF++SKI+ Y+KMW++M S SV K+ Sbjct: 116 RKGTPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSNE 175 Query: 714 DGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRTPVN 773 +G+ RV S +AFL+EST E++ QR C+ ++GG +DSKGYGV TP GS R + Sbjct: 176 EGIQRVLTS--DYAFLMESTTIEFVTQRN-CNLTQIGGLIDSKGYGVGTPMGSPYRDKIT 232 Query: 774 LAVLKLSEQGILDKLKNKWWYDKG 797 +A+L+L E+G L +K KWW G Sbjct: 233 IAILQLQEEGKLHMMKEKWWRGNG 256 >4IGR-A nrPDB Length = 258 Score = 143 bits (360), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 79/178 (44%), Positives = 112/178 (62%), Gaps = 16/178 (8%) Query: 416 NRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYG 475 NR+++VTT+LE P+VM++K+ L GN+R+EGYC+DL E+A + Y++ +V DGKYG Sbjct: 5 NRSLIVTTLLEEPFVMFRKSDRTLYGNDRFEGYCIDLLKELAHILGFSYEIRLVEDGKYG 64 Query: 476 ARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK 535 A+D + + WNGMV EL+ +AD+AVAPLTIT VRE+ IDFSKPFM+LG+SI+ +K Sbjct: 65 AQDDKGQ-WNGMVKELIDHKADLAVAPLTITHVREKAIDFSKPFMTLGVSILYRKGTP-- 121 Query: 536 PGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYE--W--------HLEDNNEE 583 D LA + + G ++ F S+ S +E W L NNEE Sbjct: 122 ---IDSADDLAKQTKIEYGAVKDGATMTFFKKSKISTFEKMWAFMSSKPSALVKNNEE 176 Score = 135 bits (341), Expect = 6e-32, Method: Compositional matrix adjust. Identities = 66/144 (45%), Positives = 96/144 (66%), Gaps = 4/144 (2%) Query: 654 RMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTA 713 R +PI+SA+DLAKQT+I YG + G+T FF++SKI+ +EKMW++M S++PS K Sbjct: 117 RKGTPIDSADDLAKQTKIEYGAVKDGATMTFFKKSKISTFEKMWAFM-SSKPSALVKNNE 175 Query: 714 DGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRTPVN 773 +G+ R + +A L+EST EYI QR C+ ++GG +DSKGYG+ TP GS R + Sbjct: 176 EGIQRTLTA--DYALLMESTTIEYITQRN-CNLTQIGGLIDSKGYGIGTPMGSPYRDKIT 232 Query: 774 LAVLKLSEQGILDKLKNKWWYDKG 797 +A+L+L E+ L +K KWW G Sbjct: 233 IAILQLQEEDKLHIMKEKWWRGSG 256 >4WXJ-A nrPDB Length = 269 Score = 103 bits (258), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 52/137 (37%), Positives = 82/137 (59%), Gaps = 1/137 (0%) Query: 657 SPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGV 716 + I S DL Q ++ +GT+ G+T +F S W+ M S +P FTK +GV Sbjct: 126 TDIGSLHDLVDQNKVQFGTIRGGATSVYFSESNDTDNRMAWNKMLSFKPDAFTKNNEEGV 185 Query: 717 ARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRTPVNLAV 776 RV+ SKG +AFL+E+T +Y QR C+ ++G + K YG+A P + R+ +++ + Sbjct: 186 DRVKLSKGTYAFLMETTNLQYYVQRN-CELTQIGESFGEKHYGIAVPLNADFRSNLSVGI 244 Query: 777 LKLSEQGILDKLKNKWW 793 L+LSE+G L KL+NKW+ Sbjct: 245 LRLSERGELFKLRNKWF 261 Score = 96.3 bits (238), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 47/113 (41%), Positives = 66/113 (58%), Gaps = 2/113 (1%) Query: 420 VVTTILESPYVMYKKNHE--QLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGAR 477 V T + PY +++ E EGNER+EGY VDL Y +A+ + + V D KYG+ Sbjct: 12 TVATRVGKPYFSWREEPEGVHYEGNERFEGYAVDLIYMLAQECKFDFNFEPVRDNKYGSY 71 Query: 478 DPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKK 530 D T W+G++ +L+ A I + LTIT R V+DF+ PFM LGISI+ K Sbjct: 72 DANTDEWDGIIRQLIDNNAQIGICDLTITQARRSVVDFTVPFMQLGISILSYK 124 >5I2K-B nrPDB Length = 293 Score = 86.3 bits (212), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 39/88 (44%), Positives = 61/88 (69%), Gaps = 4/88 (4%) Query: 447 GYCVDLAYEIAKHVRIKYKLSIVGDGKYGARD----PETKIWNGMVGELVYGRADIAVAP 502 G+C+DL ++A+ + Y++ +V DGK+G ++ K WNGM+GEL+ G+AD+ VAP Sbjct: 66 GFCIDLLIKLARTMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQADMIVAP 125 Query: 503 LTITLVREEVIDFSKPFMSLGISIMIKK 530 LTI R + I+FSKPF G++I++KK Sbjct: 126 LTINNERAQYIEFSKPFKYQGLTILVKK 153 Score = 45.1 bits (105), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 35/129 (27%), Positives = 61/129 (47%), Gaps = 9/129 (6%) Query: 673 YGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLES 732 Y T+ S +FRR M+ +M+ ++ A+ + VR +K AF+ +S Sbjct: 174 YATVKQSSVDIYFRRQ--VELSTMYRHMEKHN----YESAAEAIQAVRDNK-LHAFIWDS 226 Query: 733 TMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRTPVNLAVLKLSEQGILDKLKNKW 792 + E+ E + CD + G G+G+ K S + V+L++LK E G ++ L +K Sbjct: 227 AVLEF-EASQKCDLVTTGELFFRSGFGIGMRKDSPWKQNVSLSILKSHENGFMEDL-DKT 284 Query: 793 WYDKGECGA 801 W EC + Sbjct: 285 WVRYQECDS 293 >5CC2-A nrPDB Length = 265 Score = 84.7 bits (208), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 40/110 (36%), Positives = 70/110 (63%), Gaps = 3/110 (2%) Query: 421 VTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPE 480 V T+LE P+VM +N L ++Y+G+ +D+ ++ ++ Y++ + D KYG+ E Sbjct: 7 VVTVLEEPFVMVSEN--VLGKPKKYQGFSIDVLDALSNYLGFNYEIYVAPDHKYGSPQ-E 63 Query: 481 TKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKK 530 WNG+VGELV+ RADI ++ LTIT RE V+DF+ +M + +++++ Sbjct: 64 DGTWNGLVGELVFKRADIGISALTITPDRENVVDFTTRYMDYSVGVLLRR 113 Score = 81.3 bits (199), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 47/154 (30%), Positives = 80/154 (51%), Gaps = 10/154 (6%) Query: 654 RMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKI------AVYEKMWSYMKSAEPSV 707 R + I+S +DL+KQT+I YGT+ + + R + ++Y +MW + + S Sbjct: 112 RRGTSIQSLQDLSKQTDIPYGTVLDSAVYQHVRMKGLNPFERDSMYSQMWRMINRSNGS- 170 Query: 708 FTKTTADGVARVRKSK-GKFAFLLESTMNEYIEQRKP-CDTMKVGGNLDSKGYGVATPKG 765 + A ++K K G +AF+ ++ + EY+ P C VG + +GYG+A G Sbjct: 171 -ENNVLESQAGIQKVKYGNYAFVWDAAVLEYVAINDPDCSFYTVGNTVADRGYGIALQHG 229 Query: 766 SALRTPVNLAVLKLSEQGILDKLKNKWWYDKGEC 799 S R + +L+L + G +D LK+KWW G+C Sbjct: 230 SPYRDVFSQRILELQQSGDMDILKHKWWPKNGQC 263 >5H8N-A nrPDB Length = 285 Score = 83.6 bits (205), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 37/85 (43%), Positives = 59/85 (69%), Gaps = 2/85 (2%) Query: 446 EGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTI 505 +G+C+D+ ++++ V+ Y L +V +GK+G + +WNGM+GE+VY RA +AV LTI Sbjct: 59 KGFCIDILKKLSRTVKFTYDLYLVTNGKHGKK--VNNVWNGMIGEVVYQRAVMAVGSLTI 116 Query: 506 TLVREEVIDFSKPFMSLGISIMIKK 530 R EV+DFS PF+ GIS+M+ + Sbjct: 117 NEERSEVVDFSVPFVETGISVMVSR 141 Score = 41.2 bits (95), Expect = 0.002, Method: Compositional matrix adjust. Identities = 37/126 (29%), Positives = 60/126 (47%), Gaps = 18/126 (14%) Query: 673 YGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGV--ARVRKSKGKF-AFL 729 +GT+ +GST+ R + Y M YM TK GV A V GK AF+ Sbjct: 165 FGTVPNGSTERNIRNN----YPYMHQYM--------TKFNQKGVEDALVSLKTGKLDAFI 212 Query: 730 LESTMNEYIEQR-KPCDTMKVGGN--LDSKGYGVATPKGSALRTPVNLAVLKLSEQGILD 786 ++ + Y R + C + +G + GYG+A KGS + ++LA+L+ G ++ Sbjct: 213 YDAAVLNYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGSPWKRQIDLALLQFVGDGEME 272 Query: 787 KLKNKW 792 +L+ W Sbjct: 273 ELETLW 278 >3OEK-A nrPDB Length = 286 Score = 80.5 bits (197), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 35/85 (41%), Positives = 56/85 (65%), Gaps = 2/85 (2%) Query: 446 EGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTI 505 +G+C+D+ +A + Y L +V +GK+G + +WNGM+GE+ Y RAD+A+ LTI Sbjct: 60 KGFCIDILKRLAHTIGFSYDLYLVTNGKHGKK--IDGVWNGMIGEVFYQRADMAIGSLTI 117 Query: 506 TLVREEVIDFSKPFMSLGISIMIKK 530 R E++DFS PF+ GIS+M+ + Sbjct: 118 NEERSEIVDFSVPFVETGISVMVAR 142 Score = 41.6 bits (96), Expect = 0.002, Method: Compositional matrix adjust. Identities = 34/127 (26%), Positives = 64/127 (50%), Gaps = 16/127 (12%) Query: 671 IAYGTLDSGSTKEFFRRSKIAVYEKMWSYM-KSAEPSVFTKTTADGVARVRKSKGKF-AF 728 + +GT+ +GST++ R + Y M SYM + +P V T + GK AF Sbjct: 164 LKFGTVPNGSTEKNIRSN----YPDMHSYMVRYNQPRVEEALT-------QLKAGKLDAF 212 Query: 729 LLESTMNEYIEQR-KPCDTMKVGGN--LDSKGYGVATPKGSALRTPVNLAVLKLSEQGIL 785 + ++ + Y+ ++ + C + +G + GYG+A KGS + P++LA+L+ + Sbjct: 213 IYDAAVLNYMARKDEGCKLVTIGSGKVFATTGYGIALHKGSRWKRPIDLALLQFLGDDEI 272 Query: 786 DKLKNKW 792 + L+ W Sbjct: 273 EMLERLW 279 >2RCB-A nrPDB Length = 292 Score = 80.1 bits (196), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 38/84 (45%), Positives = 55/84 (65%), Gaps = 4/84 (4%) Query: 447 GYCVDLAYEIAKHVRIKYKLSIVGDGKYGA-RDPETKIWNGMVGELVYGRADIAVAPLTI 505 GYC+DL +A+ + ++L IVGDGKYGA RD W G+VG+L+ GRA +AV +I Sbjct: 68 GYCIDLLERLAEDLAFDFELYIVGDGKYGALRDGR---WTGLVGDLLAGRAHMAVTSFSI 124 Query: 506 TLVREEVIDFSKPFMSLGISIMIK 529 R +V+DF+ PF S + IM++ Sbjct: 125 NSARSQVVDFTSPFFSTSLGIMVR 148 Score = 44.7 bits (104), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 32/130 (24%), Positives = 61/130 (46%), Gaps = 11/130 (8%) Query: 673 YGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKF-AFLLE 731 +GT+ S + + + A + +M ++M+ TT GVA + K AF+++ Sbjct: 171 FGTVWESSAEAYIK----ASFPEMHAHMRRHS----APTTPHGVAMLTSDPPKLNAFIMD 222 Query: 732 STMNEY-IEQRKPCDTMKVGGNLDSKGYGVATPKGSALRTPVNLAVLKLSEQGILDKLKN 790 ++ +Y + C + VG +GYG+ P+ S L + ++ + + G +D L + Sbjct: 223 KSLLDYEVSIDADCKLLTVGKPFAIEGYGIGLPQNSPLTSNLSEFISRYKSSGFIDLLHD 282 Query: 791 KWWYDKGECG 800 K WY CG Sbjct: 283 K-WYKMVPCG 291 >2RC9-A nrPDB Length = 294 Score = 77.8 bits (190), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 35/83 (42%), Positives = 54/83 (65%), Gaps = 2/83 (2%) Query: 447 GYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTIT 506 GYC+DL ++A+ + + L IVGDGKYGA + W G+VG+L+ G A++AV +I Sbjct: 70 GYCIDLLEQLAEDMNFDFDLYIVGDGKYGAW--KNGHWTGLVGDLLSGTANMAVTSFSIN 127 Query: 507 LVREEVIDFSKPFMSLGISIMIK 529 R +VIDF+ PF S + I+++ Sbjct: 128 TARSQVIDFTSPFFSTSLGILVR 150 Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 31/123 (25%), Positives = 58/123 (47%), Gaps = 10/123 (8%) Query: 673 YGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKF-AFLLE 731 +GT+ S +++ R+S ++E M Y A P DGV ++ K AF+++ Sbjct: 173 FGTVRESSAEDYVRQSFPEMHEYMRRYNVPATP--------DGVQYLKNDPEKLDAFIMD 224 Query: 732 STMNEY-IEQRKPCDTMKVGGNLDSKGYGVATPKGSALRTPVNLAVLKLSEQGILDKLKN 790 + +Y + C + VG +GYG+ P S L + ++ + + G +D L + Sbjct: 225 KALLDYEVSIDADCKLLTVGKPFAIEGYGIGLPPNSPLTSNISELISQYKSHGFMDVLHD 284 Query: 791 KWW 793 KW+ Sbjct: 285 KWY 287 >4YKP-A nrPDB Length = 256 Score = 66.6 bits (161), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 38/137 (27%), Positives = 68/137 (49%), Gaps = 3/137 (2%) Query: 417 RTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGA 476 R + + ++ E P++ + E EGN+ + G D+ ++++ + Y+ D K+GA Sbjct: 8 RHLRLGSVEEQPFMFFAT--EGCEGNDCWSGMVNDMVVKLSEDLGFTYEYIQPDDRKFGA 65 Query: 477 RDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKP 536 + T WNGM+ +L+ + D+ L+ R+ ID+S PFM GI ++K + Sbjct: 66 LNKTTNEWNGMIRDLLDDKTDMIAIDLSTNSARKSAIDYSFPFMDAGIKAVVKGEGTTLN 125 Query: 537 GVFSFLDPLAYEIWMCI 553 V LD Y+ W I Sbjct: 126 QVLELLDQDKYK-WGVI 141 Score = 36.6 bits (83), Expect = 0.043, Method: Compositional matrix adjust. Identities = 17/49 (34%), Positives = 24/49 (48%) Query: 744 CDTMKVGGNLDSKGYGVATPKGSALRTPVNLAVLKLSEQGILDKLKNKW 792 CD VG S Y PK S ++ ++ +LK E+G +D L KW Sbjct: 200 CDVFSVGEEFQSFEYAFGLPKDSPYKSLIDSHLLKFREEGFIDILWEKW 248 >5TUJ-C nrPDB Length = 235 Score = 56.6 bits (135), Expect = 4e-08, Method: Composition-based stats. Identities = 33/102 (32%), Positives = 56/102 (54%), Gaps = 13/102 (12%) Query: 442 NERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVA 501 N +Y G+ +DLA +AK + +K + P T W+G++ L G+ DI ++ Sbjct: 31 NGQYTGFDIDLAKALAKELGVKVEFV-----------PTT--WDGIIPALQTGKFDIVMS 77 Query: 502 PLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLD 543 +TIT R++ +DFS P+M+ G +I++KK K F L+ Sbjct: 78 GMTITPERKKKVDFSDPYMTAGQTILVKKDNADKIKSFEDLN 119 Score = 29.3 bits (64), Expect = 9.0, Method: Composition-based stats. Identities = 34/140 (24%), Positives = 55/140 (39%), Gaps = 22/140 (15%) Query: 659 IESAEDLAK---QTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADG 715 I+S EDL K + + GT + KEF ++KI +E A+ Sbjct: 112 IKSFEDLNKPDVKVAVQLGTTSEQAAKEFLPKAKIRTFE----------------NNAEA 155 Query: 716 VARVRKSKGKFAFLLESTMNEYIEQRKP-CDTMKVGGNLDSKGYGVATPKGSA-LRTPVN 773 V + A + +S + Y ++ P + V + G A KG L VN Sbjct: 156 FQEVVSGRAD-AMVTDSPVAAYYAKKNPGLAVVVVDEPFTHEPLGFAIRKGDPELLNWVN 214 Query: 774 LAVLKLSEQGILDKLKNKWW 793 + ++ + G DKL KW+ Sbjct: 215 NWLKQMKKDGTYDKLYEKWF 234 >4ZDM-A nrPDB Length = 261 Score = 49.3 bits (116), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 24/85 (28%), Positives = 44/85 (51%) Query: 445 YEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLT 504 Y G V++ +++ + Y D K+G ++ T WNG++ +L+ + D+ V L+ Sbjct: 37 YTGVNVEIVSMMSQDLNFTYNFITPEDLKFGGKNSTTGEWNGLIRDLLDNKTDMIVVALS 96 Query: 505 ITLVREEVIDFSKPFMSLGISIMIK 529 VR+ IDFS M G+ ++K Sbjct: 97 NNAVRKADIDFSLSMMDGGLGALVK 121 Score = 35.8 bits (81), Expect = 0.077, Method: Compositional matrix adjust. Identities = 31/133 (23%), Positives = 59/133 (44%), Gaps = 9/133 (6%) Query: 664 DLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSK 723 +L Q + +G +DS + + ++ A Y ++ AE +V + +G+ R+R Sbjct: 132 ELLNQDKYQWGVVDSRNPELLLASNQNADYNRI------AEDAVKVGSYGEGLERMRA-- 183 Query: 724 GKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRTPVNLAVLKLSEQG 783 G F F+ E Y + CD +++G K S + V+ +L + EQG Sbjct: 184 GGFVFIDEIPGINY-ATKGECDIVQIGETFQPFELAFGLRKNSPFKNLVDTFMLGIREQG 242 Query: 784 ILDKLKNKWWYDK 796 ++ +L K+ K Sbjct: 243 VISELYAKYENQK 255 >4F3S-A nrPDB Length = 255 Score = 48.1 bits (113), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 34/107 (31%), Positives = 57/107 (53%), Gaps = 23/107 (21%) Query: 415 ENRTIVVTTILESPYVMYKKNHEQLEGN--ERYEGYCVDLAYEIAKHVRIKYKLSIVGDG 472 E RT+ V SP +++K +L+G E + YC ++H KL+I Sbjct: 7 EGRTLNVAVSPASPPMLFKSADGKLQGIDLELFSSYCQ------SRHC----KLNIT--- 53 Query: 473 KYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPF 519 +Y W+GM+G + G+AD+A + ++IT R++VIDFS+P+ Sbjct: 54 EYA--------WDGMLGAVASGQADVAFSGISITDKRKKVIDFSEPY 92 >4ZV2-A nrPDB Length = 233 Score = 46.2 bits (108), Expect = 6e-05, Method: Composition-based stats. Identities = 27/93 (29%), Positives = 49/93 (52%), Gaps = 13/93 (13%) Query: 442 NERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVA 501 N + G+ +DLA IAK + +K + + ++G++ L G+ D+ +A Sbjct: 29 NGKLVGFDIDLAKAIAKKLGVKVEFKPMD-------------FDGIIPALQSGKIDVVIA 75 Query: 502 PLTITLVREEVIDFSKPFMSLGISIMIKKPQKS 534 +TIT R++ +DFS P+ G +I++KK S Sbjct: 76 GMTITEERKKQVDFSDPYFEAGQAIVVKKGNDS 108 Score = 33.5 bits (75), Expect = 0.44, Method: Composition-based stats. Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 1/58 (1%) Query: 737 YIEQRKPCDTMKVGGNLDSKGYGVATPKG-SALRTPVNLAVLKLSEQGILDKLKNKWW 793 Y++Q VG + YG+A KG S L +N A+ ++ + G DK+ KW+ Sbjct: 174 YVKQNPNAGVKIVGETFSGEPYGIAVRKGNSELLEKINKALEEMKKDGTYDKIYEKWF 231 >4IO3-A nrPDB Length = 248 Score = 46.2 bits (108), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 22/61 (36%), Positives = 32/61 (52%) Query: 736 EYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRTPVNLAVLKLSEQGILDKLKNKWWYD 795 EY+ C+ VG + D +G+ TPK +++ +L L E GILD LK KW+ Sbjct: 185 EYVTNNIYCNLTLVGEDFDKSTFGIVTPKEWLYAKDLDVNILSLRETGILDNLKKKWFQT 244 Query: 796 K 796 K Sbjct: 245 K 245 Score = 34.3 bits (77), Expect = 0.22, Method: Compositional matrix adjust. Identities = 23/87 (26%), Positives = 40/87 (45%), Gaps = 9/87 (10%) Query: 444 RYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPL 503 + GY +DL ++ K+ V D + P + G+V L G DIA+ + Sbjct: 36 KLTGYVLDLIE------YLRDKMGFVADVQLA---PPNTSYTGLVLALANGDYDIAIGDI 86 Query: 504 TITLVREEVIDFSKPFMSLGISIMIKK 530 T+T R E++ FS + I+++K Sbjct: 87 TVTSARREIVAFSNSISDNSMRILMRK 113 >3K4U-A nrPDB Length = 245 Score = 45.8 bits (107), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 27/84 (32%), Positives = 49/84 (58%), Gaps = 13/84 (15%) Query: 447 GYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTIT 506 G+ VDLA E+AK + +K KL P + W+G++ LV + DI ++ +TI+ Sbjct: 29 GFDVDLAREMAKAMGVKLKLV-----------PTS--WDGLIPGLVTEKFDIIISGMTIS 75 Query: 507 LVREEVIDFSKPFMSLGISIMIKK 530 R ++F +P++ +G S+++KK Sbjct: 76 QERNLRVNFVEPYIVVGQSLLVKK 99 >4PSH-A nrPDB Length = 227 Score = 45.8 bits (107), Expect = 9e-05, Method: Composition-based stats. Identities = 30/106 (28%), Positives = 55/106 (51%), Gaps = 13/106 (12%) Query: 437 EQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRA 496 E ++ N G+ VDLA EIA+ R+ +L IV ++G++ L+ + Sbjct: 23 EFVDENGNIVGFDVDLAKEIAR--RLGVELKIV-----------DMTFDGLIPSLLTKKI 69 Query: 497 DIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFL 542 D+ ++ +TIT R++V+ FS P+ G I+++K +P + L Sbjct: 70 DVIISGMTITEERKKVVAFSDPYFDAGQVIVVRKDSDFRPKTYEDL 115 >5JOS-A nrPDB Length = 247 Score = 44.3 bits (103), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 25/92 (27%), Positives = 48/92 (52%), Gaps = 13/92 (14%) Query: 444 RYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPL 503 +Y G+ +D+A +AK + +K + P T W ++ +L + DIA+ + Sbjct: 44 QYTGFDIDVAKSLAKSLGVKVEFV-----------PTT--WPTLMSDLQADKFDIAMGGV 90 Query: 504 TITLVREEVIDFSKPFMSLGISIMIKKPQKSK 535 T+T R++ DFS P+M+ G + +++K K Sbjct: 91 TVTPERQKKADFSDPYMTFGKTPLVRKEDADK 122 >1GGG-A nrPDB Length = 226 Score = 41.6 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 26/92 (28%), Positives = 48/92 (52%), Gaps = 13/92 (14%) Query: 438 QLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRAD 497 + + + Y G+ VDL IAK +++ Y+L + ++G++ L D Sbjct: 17 EFKQGDLYVGFDVDLWAAIAKELKLDYELKPMD-------------FSGIIPALQTKNVD 63 Query: 498 IAVAPLTITLVREEVIDFSKPFMSLGISIMIK 529 +A+A +TIT R++ IDFS + G+ +M+K Sbjct: 64 LALAGITITDERKKAIDFSDGYYKSGLLVMVK 95 Score = 39.7 bits (91), Expect = 0.006, Method: Composition-based stats. Identities = 20/46 (43%), Positives = 30/46 (65%), Gaps = 1/46 (2%) Query: 749 VGGNLDSKGYGVATPKGS-ALRTPVNLAVLKLSEQGILDKLKNKWW 793 VG +L+++ YG+A PKGS LR VN A+ L E G +++ KW+ Sbjct: 176 VGDSLEAQQYGIAFPKGSDELRDKVNGALKTLRENGTYNEIYKKWF 221 >5OTA-A nrPDB Length = 265 Score = 40.8 bits (94), Expect = 0.003, Method: Compositional matrix adjust. Identities = 27/100 (27%), Positives = 46/100 (46%), Gaps = 17/100 (17%) Query: 421 VTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPE 480 +T E Y Y N + G + G+ +DL ++ K + I+ K Sbjct: 7 ITIATEGSYAPY--NFKDAGG--KLIGFDIDLGNDLCKRMNIECKFV------------- 49 Query: 481 TKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFM 520 + W+G++ L GR D +A + I RE+VI FS+P++ Sbjct: 50 EQAWDGIIPSLTAGRYDAIMAAMGIQPAREKVIAFSRPYL 89 >4F3P-A nrPDB Length = 249 Score = 40.0 bits (92), Expect = 0.004, Method: Compositional matrix adjust. Identities = 24/92 (26%), Positives = 45/92 (48%), Gaps = 13/92 (14%) Query: 438 QLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRAD 497 + + ++Y G+ +DL EIAK YK+ + + G++ L D Sbjct: 38 EFKQGDKYVGFDLDLWAEIAKGAGWTYKIQPMD-------------FAGLIPALQTQNID 84 Query: 498 IAVAPLTITLVREEVIDFSKPFMSLGISIMIK 529 +A++ +TI R + IDFS P+ G++ M++ Sbjct: 85 VALSGMTIKEERRKAIDFSDPYYDSGLAAMVQ 116 Score = 29.6 bits (65), Expect = 6.2, Method: Compositional matrix adjust. Identities = 14/45 (31%), Positives = 21/45 (46%) Query: 749 VGGNLDSKGYGVATPKGSALRTPVNLAVLKLSEQGILDKLKNKWW 793 G + YG+ PKGS L VN + ++ G K+ KW+ Sbjct: 197 AGAPVSGDKYGIGFPKGSPLVAKVNAELARMKADGRYAKIYKKWF 241 >2PYY-A nrPDB Length = 228 Score = 40.0 bits (92), Expect = 0.005, Method: Compositional matrix adjust. Identities = 19/48 (39%), Positives = 25/48 (52%) Query: 749 VGGNLDSKGYGVATPKGSALRTPVNLAVLKLSEQGILDKLKNKWWYDK 796 VG L + YG+ P S R P+N A+L L E G L +KW+ K Sbjct: 177 VGSILREESYGIILPNNSPYRKPINQALLNLKENGTYQSLYDKWFDPK 224 Score = 37.0 bits (84), Expect = 0.043, Method: Compositional matrix adjust. Identities = 28/113 (24%), Positives = 54/113 (47%), Gaps = 20/113 (17%) Query: 417 RTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGA 476 + ++V T + P+V+ K G+ +DL IA + I+ KL +Y + Sbjct: 3 QPLLVATRVIPPFVLSNKGE--------LSGFSIDLWRSIATQIGIESKLI-----EYSS 49 Query: 477 RDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIK 529 PE ++ + + ++ +A ++IT RE+ DFS P + G+ IM++ Sbjct: 50 V-PE------LISAIKDNKVNLGIAAISITAEREQNFDFSLPIFASGLQIMVR 95 >4H5F-A nrPDB Length = 243 Score = 39.3 bits (90), Expect = 0.008, Method: Composition-based stats. Identities = 26/97 (26%), Positives = 48/97 (49%), Gaps = 13/97 (13%) Query: 439 LEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADI 498 ++G + G +D+A IA + +K ++ + ++ ++ L G+AD+ Sbjct: 31 VDGKNQVVGADIDMAQAIADELGVKLEILSMS-------------FDNVLTSLQTGKADL 77 Query: 499 AVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK 535 AVA ++ T R+EV DFS P+ IS ++ K K Sbjct: 78 AVAGISATDERKEVFDFSIPYYENKISFLVHKADVEK 114 >6FXG-A nrPDB Length = 227 Score = 38.5 bits (88), Expect = 0.011, Method: Compositional matrix adjust. Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 13/93 (13%) Query: 441 GNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAV 500 G +++ G VD+ E+AK K ++S G ++ + L G+ D + Sbjct: 22 GQKKWVGIDVDIMQEVAKINDWKLEMSYPG-------------FDAALQNLKAGQVDGII 68 Query: 501 APLTITLVREEVIDFSKPFMSLGISIMIKKPQK 533 A +TIT R+E DFS P+ + ++I K K Sbjct: 69 AGMTITDERKETFDFSNPYYTSALTIATTKDSK 101 >4KPT-A nrPDB Length = 251 Score = 38.5 bits (88), Expect = 0.014, Method: Compositional matrix adjust. Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 13/93 (13%) Query: 441 GNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAV 500 G +++ G VD+ E+AK K ++S G ++ + L G+ D + Sbjct: 46 GQKKWVGIDVDIMQEVAKINDWKLEMSYPG-------------FDAALQNLKAGQVDGII 92 Query: 501 APLTITLVREEVIDFSKPFMSLGISIMIKKPQK 533 A +TIT R+E DFS P+ + ++I K K Sbjct: 93 AGMTITDERKETFDFSNPYYTSALTIATTKDSK 125 >4ZEF-A nrPDB Length = 251 Score = 37.4 bits (85), Expect = 0.028, Method: Compositional matrix adjust. Identities = 18/37 (48%), Positives = 24/37 (64%) Query: 494 GRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKK 530 G+AD VA +TIT R++ DFS P+ GI I +KK Sbjct: 86 GQADGMVAGMTITDDRKKAFDFSVPYFDSGIQIAVKK 122 >4KQP-A nrPDB Length = 232 Score = 36.2 bits (82), Expect = 0.065, Method: Compositional matrix adjust. Identities = 22/85 (25%), Positives = 41/85 (48%), Gaps = 13/85 (15%) Query: 442 NERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVA 501 ++++ G VDL IAK+ K K + +G + V + G AD ++ Sbjct: 27 DKQFTGIDVDLLNAIAKNQGFKLKWNFIG-------------FQAAVDSVQSGHADGMMS 73 Query: 502 PLTITLVREEVIDFSKPFMSLGISI 526 ++IT R++V D+ P+ S ++I Sbjct: 74 GMSITDARKQVFDYGSPYYSSNLTI 98 >5ORE-A nrPDB Length = 263 Score = 35.8 bits (81), Expect = 0.093, Method: Compositional matrix adjust. Identities = 25/97 (25%), Positives = 48/97 (49%), Gaps = 15/97 (15%) Query: 444 RYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPL 503 + +G+ +DLA + + ++K K IV + W+G++ L + D +A + Sbjct: 25 KLDGFEIDLANALCE--KMKAKCQIV-----------AQNWDGIMPSLTGKKYDAIMAAM 71 Query: 504 TITLVREEVIDFSKPFMSL--GISIMIKKPQKSKPGV 538 ++T R+EVI FS P+ + G ++M PG+ Sbjct: 72 SVTPKRQEVIGFSIPYAAGINGFAVMGDSKLAEMPGL 108 >2Q2A-A nrPDB Length = 272 Score = 35.0 bits (79), Expect = 0.15, Method: Compositional matrix adjust. Identities = 21/84 (25%), Positives = 38/84 (45%), Gaps = 13/84 (15%) Query: 447 GYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTIT 506 G+ VDL + K + Y+L +G W+ + L D+ ++ +TIT Sbjct: 65 GFDVDLLDAVMKAAGLDYELKNIG-------------WDPLFASLQSKEVDMGISGITIT 111 Query: 507 LVREEVIDFSKPFMSLGISIMIKK 530 R++ DFS P+ I++K+ Sbjct: 112 DERKQSYDFSDPYFEATQVILVKQ 135 >2IEE-A nrPDB Length = 271 Score = 34.7 bits (78), Expect = 0.17, Method: Composition-based stats. Identities = 26/95 (27%), Positives = 45/95 (47%), Gaps = 14/95 (14%) Query: 436 HEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGR 495 H+ G+++ GY V++ E AK + +K + +G +GM+ + G+ Sbjct: 37 HDTDSGSDKLTGYEVEVVREAAKRLGLKVEFKEMG-------------IDGMLTAVNSGQ 83 Query: 496 ADIAVAPLTITLVREEVIDFSKPF-MSLGISIMIK 529 D A + +T REE FS P+ S G +I+ K Sbjct: 84 VDAAANDIDVTKDREEKFAFSTPYKYSYGTAIVRK 118 >4YMX-A nrPDB Length = 260 Score = 34.7 bits (78), Expect = 0.18, Method: Composition-based stats. Identities = 23/81 (28%), Positives = 42/81 (51%), Gaps = 13/81 (16%) Query: 436 HEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGR 495 H+ G + G+ +D+A IAK + +K ++ +D + K G++ L GR Sbjct: 53 HKVEGGKDEIVGFDIDIANAIAKKLGVKLEI----------KDMDFK---GLIPALQAGR 99 Query: 496 ADIAVAPLTITLVREEVIDFS 516 D+ +A +T T R++ +DFS Sbjct: 100 VDMVIAGMTPTAERKKSVDFS 120 >3I6V-A nrPDB Length = 232 Score = 34.7 bits (78), Expect = 0.19, Method: Composition-based stats. Identities = 14/37 (37%), Positives = 25/37 (67%) Query: 484 WNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFM 520 W+ ++ LV G D +A ++IT R+EVIDF++ ++ Sbjct: 53 WDSIIPNLVSGNYDTIIAGMSITDERDEVIDFTQNYI 89 >4I62-A nrPDB Length = 269 Score = 34.3 bits (77), Expect = 0.22, Method: Composition-based stats. Identities = 21/92 (22%), Positives = 48/92 (52%), Gaps = 13/92 (14%) Query: 439 LEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADI 498 ++G + G ++LA IA + ++ +LS + ++ ++ + G+AD+ Sbjct: 58 VDGKNQIVGSDIELAKAIATELGVELELSPMS-------------FDNVLASVQSGKADL 104 Query: 499 AVAPLTITLVREEVIDFSKPFMSLGISIMIKK 530 A++ ++ T R +V DFS P+ + +++KK Sbjct: 105 AISGVSKTDERSKVFDFSTPYYTAKNKLIVKK 136 >4FGU-A nrPDB Length = 429 Score = 34.3 bits (77), Expect = 0.25, Method: Compositional matrix adjust. Identities = 14/43 (32%), Positives = 27/43 (62%) Query: 182 VTARSVGNIKDIQEFRRIIEEMDRRQEKRYLIDCEVERINTIL 224 + R + N D++E R++ EE+ R + R+LI+ V +I ++L Sbjct: 302 IMKRKLMNTNDLEESRQLTEEIQRHLDARHLIEKSVRKIVSLL 344 >3TQL-A nrPDB Length = 227 Score = 32.7 bits (73), Expect = 0.67, Method: Compositional matrix adjust. Identities = 17/87 (19%), Positives = 38/87 (43%), Gaps = 13/87 (14%) Query: 444 RYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPL 503 + EG+ D+ + K ++ +S + W+ ++ L G+ D + Sbjct: 23 QVEGFGADIVKAVCKQMQAVCTIS-------------NQPWDSLIPSLKLGKFDALFGGM 69 Query: 504 TITLVREEVIDFSKPFMSLGISIMIKK 530 IT R++ +DF+ P+ + +S + K Sbjct: 70 NITTARQKEVDFTDPYYTNSVSFIADK 96 >5EYF-A nrPDB Length = 245 Score = 32.3 bits (72), Expect = 0.97, Method: Compositional matrix adjust. Identities = 27/91 (29%), Positives = 45/91 (49%), Gaps = 12/91 (13%) Query: 446 EGYCVDLAYEIAKHVRIKYKLSIVGD-GKYGARDPETKIWNGMVGELVYGRADIAVAPLT 504 +G+ VD+A I K I+GD GK + +K + L G D +A +T Sbjct: 39 QGFDVDIAKAITKK--------ILGDNGKTEFVEVTSKT---RIPLLKNGNIDAIIATMT 87 Query: 505 ITLVREEVIDFSKPFMSLGISIMIKKPQKSK 535 IT R++ +DFS + G ++++KK + K Sbjct: 88 ITDERKKQVDFSDVYFDAGQALLVKKGSQIK 118 Score = 30.0 bits (66), Expect = 4.1, Method: Compositional matrix adjust. Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 1/51 (1%) Query: 749 VGGNLDSKGYGVATPKGSA-LRTPVNLAVLKLSEQGILDKLKNKWWYDKGE 798 VGG ++ YG+A KG VN A+ ++ G DK+ KW+ ++ E Sbjct: 191 VGGTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETE 241 >5HPQ-A nrPDB Length = 255 Score = 31.2 bits (69), Expect = 2.2, Method: Compositional matrix adjust. Identities = 28/109 (25%), Positives = 53/109 (48%), Gaps = 22/109 (20%) Query: 445 YEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLT 504 Y G+ VD+A +A+ + KL +V P + W ++ + R DIA++ ++ Sbjct: 45 YAGFDVDMAQRLAES--LGAKLVVV---------PTS--WPNLMRDFADDRFDIAMSGIS 91 Query: 505 ITLVREEVIDFSKPFMSLG---ISIMIKKP------QKSKPGVFSFLDP 544 I L R+ FS P++ G I++ ++ Q +PGV + ++P Sbjct: 92 INLERQRQAYFSIPYLRDGKTPITLCSEEARFQTLEQIDQPGVTAIVNP 140 >5OCH-A nrPDB Length = 612 Score = 30.8 bits (68), Expect = 2.7, Method: Compositional matrix adjust. Identities = 23/91 (25%), Positives = 44/91 (48%), Gaps = 15/91 (16%) Query: 182 VTARSVGNIKDIQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYM- 240 V ++GN++ ++ F M++R+E+RY E+E E++ RG Sbjct: 224 VADEALGNVRTVRAF-----AMEQREEERY--GAELEACRCRAEEL------GRGIALFQ 270 Query: 241 -LANLGFTDIVLERVMHGGANITGFQIVNNE 270 L+N+ F +VL + GG+ + G Q+ + Sbjct: 271 GLSNIAFNCMVLGTLFIGGSLVAGQQLTGGD 301 >6GI9-A nrPDB Length = 373 Score = 30.4 bits (67), Expect = 3.1, Method: Compositional matrix adjust. Identities = 17/61 (27%), Positives = 30/61 (49%) Query: 458 KHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSK 517 + VR ++ I+G G Y A E I G++ + +GR IA L L ++ ++ + Sbjct: 288 QKVRERFHGVIIGAGAYTAEKAEDLIGKGLIDAVAFGRDYIANPDLVARLQKKAELNPQR 347 Query: 518 P 518 P Sbjct: 348 P 348 >6JEQ-A nrPDB Length = 675 Score = 30.4 bits (67), Expect = 3.4, Method: Compositional matrix adjust. Identities = 13/31 (41%), Positives = 18/31 (58%) Query: 153 EKFVYLYDTERGFSILQAIMEAAVQNNWQVT 183 E FV LY+TE G + + M+ VQ W +T Sbjct: 61 EAFVVLYETEDGMPVKELPMKRDVQGTWTLT 91 >5VXG-A nrPDB Length = 358 Score = 30.4 bits (67), Expect = 3.6, Method: Compositional matrix adjust. Identities = 18/54 (33%), Positives = 29/54 (53%), Gaps = 2/54 (3%) Query: 637 IIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKI 690 +++ TANL T+ERM SP + E+ + E+A TL G+ RS++ Sbjct: 166 LVVDGETANLVYEKTLERMTSPDVTEEEF--RNELAALTLGCGAAAMVMARSEL 217 >5LOM-A nrPDB Length = 269 Score = 30.4 bits (67), Expect = 3.6, Method: Compositional matrix adjust. Identities = 27/111 (24%), Positives = 54/111 (48%), Gaps = 18/111 (16%) Query: 418 TIVVTTILES-PYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGA 476 TI V T+ ++ PY +GN + G+ ++L +A + K K +V G+ Sbjct: 32 TISVGTMGDAKPYAF-----TTADGN--FTGFDIELFLNVAGRLGFK-KEQVVFTGQE-- 81 Query: 477 RDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIM 527 ++ ++ + GR D+A A + T R+E +DFS +++ +S++ Sbjct: 82 -------FSALMPSVANGRFDVAAAAIGTTAKRKETVDFSDGYLAGFLSVL 125 >4G4P-A nrPDB Length = 244 Score = 30.0 bits (66), Expect = 5.2, Method: Composition-based stats. Identities = 23/87 (26%), Positives = 39/87 (44%), Gaps = 13/87 (14%) Query: 444 RYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPL 503 +Y G VDL IAK + L +G ++ V + + D +A + Sbjct: 44 KYIGIDVDLLDAIAKDQDFEVDLKPLG-------------FDSAVQAIQSKQIDGMIAGM 90 Query: 504 TITLVREEVIDFSKPFMSLGISIMIKK 530 +IT R++ DFS P+ G+ + +KK Sbjct: 91 SITDERKKSFDFSDPYFDSGLQLAVKK 117 >5GZU-A nrPDB Length = 885 Score = 29.3 bits (64), Expect = 8.8, Method: Compositional matrix adjust. Identities = 27/113 (23%), Positives = 49/113 (43%), Gaps = 19/113 (16%) Query: 730 LESTMNEYIEQRKPCDTMKVGG--------NLDSKGYGVATPKGSALRTPVNLAVLKLSE 781 ++ST+ Y+ P + + VGG N+++KG G++ GS +P + +L Sbjct: 259 VDSTVKLYLNNGVPAEKLMVGGAFYSRVWQNVENKGTGLSEKAGSQAGSPGTIVYSELVN 318 Query: 782 QGILDKLKNKWWYDKGECGAKDSGS-----KDKTSA------LSLSNVAGVFY 823 I ++W D + +GS +D SA + +N+AG Y Sbjct: 319 NYINKNGYTRYWDDTAKAPYLFNGSTFISYEDTASAAYKAEYIKQNNLAGFMY 371 >4MS4-A nrPDB Length = 420 Score = 28.9 bits (63), Expect = 9.2, Method: Compositional matrix adjust. Identities = 13/47 (27%), Positives = 28/47 (59%), Gaps = 1/47 (2%) Query: 348 IERALKMVQVQGMTGNIQFDTYGRRTNYTIDVYEMKVSGSRKAGYWN 394 I RA+ +G++G++ FD G R +T+ + +++ +K GY++ Sbjct: 345 IYRAMNSSSFEGVSGHVVFDASGSRMAWTL-IEQLQGGSYKKIGYYD 390 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5IDF-B nrPDB 1324 0.0 6QKC-A nrPDB 1159 0.0 4U1Y-A nrPDB 1126 0.0 5KUF-A nrPDB 1017 0.0 5IPR-B nrPDB 771 0.0 4PE5-B nrPDB 706 0.0 6IRA-D nrPDB 650 0.0 5UP2-B nrPDB 646 0.0 5UOW-A nrPDB 624 e-179 5KUH-A nrPDB 622 e-178 5FXI-A nrPDB 617 e-177 5L2E-A nrPDB 527 e-150 5UN1-G nrPDB 483 e-136 5UN1-B nrPDB 476 e-134 3DP4-A nrPDB 229 5e-60 3FAT-A nrPDB 228 8e-60 1YAE-A nrPDB 228 8e-60 5O9A-A nrPDB 227 2e-59 2XXT-A nrPDB 212 5e-55 4MF3-A nrPDB 210 2e-54 4IGR-A nrPDB 208 1e-53 5EHM-A nrPDB 203 2e-52 5IKB-A nrPDB 200 2e-51 5DT6-A nrPDB 193 3e-49 4WXJ-A nrPDB 170 2e-42 5CC2-A nrPDB 170 3e-42 5I2K-B nrPDB 161 2e-39 4YKP-A nrPDB 159 4e-39 5H8N-A nrPDB 152 7e-37 2RC9-A nrPDB 146 4e-35 2RCB-A nrPDB 141 9e-34 3OEK-A nrPDB 137 2e-32 4ZDM-A nrPDB 126 3e-29 5TUJ-C nrPDB 126 4e-29 4ZV2-A nrPDB 104 2e-22 4PSH-A nrPDB 103 4e-22 5JOS-A nrPDB 99 5e-21 3K4U-A nrPDB 96 8e-20 4IO3-A nrPDB 91 3e-18 1GGG-A nrPDB 91 3e-18 4F3S-A nrPDB 85 1e-16 Sequences not found previously or not previously below threshold: 4F3P-A nrPDB 89 8e-18 4YMX-A nrPDB 79 7e-15 2Q2A-A nrPDB 78 2e-14 4H5F-A nrPDB 75 1e-13 4G4P-A nrPDB 74 3e-13 4ZEF-A nrPDB 72 9e-13 4I62-A nrPDB 71 3e-12 2PYY-A nrPDB 70 5e-12 5HPQ-A nrPDB 66 5e-11 2IEE-A nrPDB 65 2e-10 5EYF-A nrPDB 63 4e-10 4OEN-A nrPDB 61 3e-09 4KPT-A nrPDB 60 5e-09 5LOM-A nrPDB 59 6e-09 6FXG-A nrPDB 59 6e-09 5OTA-A nrPDB 59 1e-08 3TQL-A nrPDB 57 2e-08 2Y7I-A nrPDB 56 7e-08 5ORE-A nrPDB 56 8e-08 3VV5-A nrPDB 55 1e-07 1IIT-A nrPDB 54 3e-07 4KQP-A nrPDB 54 3e-07 3I6V-A nrPDB 54 3e-07 5X2M-A nrPDB 52 1e-06 1HSL-A nrPDB 52 1e-06 5OWF-A nrPDB 52 1e-06 4F11-A nrPDB 49 1e-05 3DEL-B nrPDB 46 5e-05 1YK0-A nrPDB 45 2e-04 4Q0C-A nrPDB 44 2e-04 2Q88-A nrPDB 40 0.006 4GNR-A nrPDB 39 0.010 4MLC-A nrPDB 38 0.020 3A3K-A nrPDB 34 0.21 1RHC-A nrPDB 34 0.35 4BIM-A nrPDB 33 0.75 1X87-A nrPDB 32 0.80 2O1M-A nrPDB 32 1.2 2FKN-A nrPDB 31 2.3 1R85-A nrPDB 31 2.5 3C04-A nrPDB 30 4.2 4DX0-A nrPDB 29 7.5 3AXY-C nrPDB 29 9.5 3QS1-A nrPDB 29 9.8 >5IDF-B nrPDB Length = 874 Score = 1324 bits (3427), Expect = 0.0, Method: Composition-based stats. Identities = 858/865 (99%), Positives = 861/865 (99%) Query: 24 FPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFSVTNA 83 FPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFSVTNA Sbjct: 10 FPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFSVTNA 69 Query: 84 FCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSFPTDADVQFVIQMRPALKGAI 143 FCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSFPTDADVQFVIQMRPALKGAI Sbjct: 70 FCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSFPTDADVQFVIQMRPALKGAI 129 Query: 144 LSLLGYYKWEKFVYLYDTERGFSILQAIMEAAVQNNWQVTARSVGNIKDIQEFRRIIEEM 203 LSLL YYKWEKFVYLYDTERGFS+LQAIMEAAVQNNWQVTARSVGNIKD+QEFRRIIEEM Sbjct: 130 LSLLSYYKWEKFVYLYDTERGFSVLQAIMEAAVQNNWQVTARSVGNIKDVQEFRRIIEEM 189 Query: 204 DRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANLGFTDIVLERVMHGGANITG 263 DRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANLGFTDI+LERVMHGGANITG Sbjct: 190 DRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANLGFTDILLERVMHGGANITG 249 Query: 264 FQIVNNENPMVQQFIQRWVRLDEREFPEAKNAPLKYTSALTHDAILVIAEAFRYLRRQRV 323 FQIVNNENPMVQQFIQRWVRLDE EFPEAKNAPLKYTSALTHDAILVIAEAFRYLRRQRV Sbjct: 250 FQIVNNENPMVQQFIQRWVRLDECEFPEAKNAPLKYTSALTHDAILVIAEAFRYLRRQRV 309 Query: 324 DVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNIQFDTYGRRTNYTIDVYEMK 383 DVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNIQFDTYGRRTNYTIDVYEMK Sbjct: 310 DVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNIQFDTYGRRTNYTIDVYEMK 369 Query: 384 VSGSRKAGYWNEYERFVPFSDQQISNDSSSSENRTIVVTTILESPYVMYKKNHEQLEGNE 443 VSGSRKAGYWNEYERFVPFSDQQISNDSSSSENRTIVVTTILESPYVMYKKNHEQLEGNE Sbjct: 370 VSGSRKAGYWNEYERFVPFSDQQISNDSSSSENRTIVVTTILESPYVMYKKNHEQLEGNE 429 Query: 444 RYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPL 503 RYEGYCVDLAYEIAKHV IKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPL Sbjct: 430 RYEGYCVDLAYEIAKHVGIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPL 489 Query: 504 TITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVV 563 TITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVV Sbjct: 490 TITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVV 549 Query: 564 LFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSLGAFMQQGCDISPRSLS 623 LFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSLGAFMQQGCDISPRSLS Sbjct: 550 LFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSLGAFMQQGCDISPRSLS 609 Query: 624 GRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKE 683 GRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKE Sbjct: 610 GRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKE 669 Query: 684 FFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRKP 743 FFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRKP Sbjct: 670 FFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRKP 729 Query: 744 CDTMKVGGNLDSKGYGVATPKGSALRTPVNLAVLKLSEQGILDKLKNKWWYDKGECGAKD 803 CDTMKVGGNLDSKGYGVATPKGSAL TPVNLAVLKLSEQGILDKLKNKWWYDKGECGAKD Sbjct: 730 CDTMKVGGNLDSKGYGVATPKGSALGTPVNLAVLKLSEQGILDKLKNKWWYDKGECGAKD 789 Query: 804 SGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCYKSRAESKRMKLTKNTQNFKPA 863 SGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCYKSRAESKRMKLTKNTQNFKPA Sbjct: 790 SGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCYKSRAESKRMKLTKNTQNFKPA 849 Query: 864 PATNTQNYATYREGYNVYGTESVKI 888 PATNTQNYATYREGYNVYGTESVKI Sbjct: 850 PATNTQNYATYREGYNVYGTESVKI 874 >6QKC-A nrPDB Length = 915 Score = 1159 bits (2998), Expect = 0.0, Method: Composition-based stats. Identities = 596/852 (69%), Positives = 698/852 (81%), Gaps = 20/852 (2%) Query: 11 FLVLGLLGHSHGG---------FPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEK 61 F G LG G FPN I IGGLF QEH+AFRFA+ TE Sbjct: 7 FFCTGFLGAVVGADYKDDDDKNFPNNIQIGGLFPNQQSQEHAAFRFALS------QLTEP 60 Query: 62 PFHLNYHVDHLDSSNSFSVTNAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTP 121 P L +D ++ S+SF +T FCSQFS+GVYAIFGFY++ ++N LTSFCGALH F+TP Sbjct: 61 P-KLLPQIDIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITP 119 Query: 122 SFPTDADVQFVIQMRPALKGAILSLLGYYKWEKFVYLYDTERGFSILQAIMEAAVQNNWQ 181 SFP D QFV+Q+RP L+ A++S++ +YKW+ FVY+YD +RG S+LQ +++ A + NWQ Sbjct: 120 SFPVDTSNQFVLQLRPELQEALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQ 179 Query: 182 VTARSVGNIKDIQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYML 241 VTA ++ + + +R + +++++++E+ ++DCE ER+N IL Q+V L K+ GYHY+L Sbjct: 180 VTAVNILTTTE-EGYRMLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYIL 238 Query: 242 ANLGFTDIVLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNAPLKYTS 301 ANLGF DI L + GAN+TGFQ+VN + + + +Q+W D R+ KYTS Sbjct: 239 ANLGFMDIDLNKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDSRDHTRVDWKRPKYTS 298 Query: 302 ALTHDAILVIAEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMT 361 ALT+D + V+AEAF+ LRRQR+D+SRRG+AGDCLANPAVPW QGIDI+RAL+ V+ +G+T Sbjct: 299 ALTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLT 358 Query: 362 GNIQFDTYGRRTNYTIDVYEMKVSGSRKAGYWNEYERFVPF-SDQQISNDSSSSENRTIV 420 GN+QF+ GRRTNYT+ V EMK G RK GYWNE ++FVP +D Q D+SS +NRT + Sbjct: 359 GNVQFNEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYI 418 Query: 421 VTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPE 480 VTTILE PYVM KKN Q EGN+RYEGYCV+LA EIAKHV Y+L IV DGKYGARDP+ Sbjct: 419 VTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPD 478 Query: 481 TKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFS 540 TK WNGMVGELVYGRAD+AVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFS Sbjct: 479 TKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFS 538 Query: 541 FLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIF 600 FLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWH E+ EE RD Q+ D NEFGIF Sbjct: 539 FLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEF-EEGRD-QTTSDQSNEFGIF 596 Query: 601 NSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIE 660 NSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIE Sbjct: 597 NSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIE 656 Query: 661 SAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVR 720 SAEDLAKQTEIAYGTL++GSTKEFFRRSKIAV+EKMW+YMKSAEPSVF +TT +G+ RVR Sbjct: 657 SAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVR 716 Query: 721 KSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRTPVNLAVLKLS 780 KSKGK+A+LLESTMNEYIEQRKPCDTMKVGGNLDSKGYG+ATPKGSALR PVNLAVLKLS Sbjct: 717 KSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLS 776 Query: 781 EQGILDKLKNKWWYDKGECGAKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEF 840 EQG+LDKLK+KWWYDKGECG+KDSGSKDKTSALSLSNVAGVFYIL+GGLGLAM+VALIEF Sbjct: 777 EQGVLDKLKSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEF 836 Query: 841 CYKSRAESKRMK 852 CYKSR+ESKRMK Sbjct: 837 CYKSRSESKRMK 848 >4U1Y-A nrPDB Length = 819 Score = 1126 bits (2913), Expect = 0.0, Method: Composition-based stats. Identities = 597/830 (71%), Positives = 709/830 (85%), Gaps = 19/830 (2%) Query: 26 NTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFSVTNAFC 85 N+I IGGLF R QE+SAFR + ++T++ F L H+D+L+ +NSF+VTNAFC Sbjct: 1 NSIQIGGLFPRGADQEYSAFRVGMVQFSTSE------FRLTPHIDNLEVANSFAVTNAFC 54 Query: 86 SQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSFPTDADVQFVIQMRPALKGAILS 145 SQFSRGVYAIFGFYD+ S+NT+TSFCG LH SF+TPSFPTD FVIQMRP LKGA+LS Sbjct: 55 SQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLS 114 Query: 146 LLGYYKWEKFVYLYDTERGFSILQAIMEAAVQNNWQVTARSVGNI---KDIQEFRRIIEE 202 L+ YY+W+KF YLYD++RG S LQA++++A + WQVTA +VGNI K + +R + ++ Sbjct: 115 LIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQD 174 Query: 203 MDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANLGFTDIVLERVMHGGANIT 262 ++ ++E+R ++DCE +++N I++QV+ +GKH +GYHY++ANLGFTD L ++ GGA ++ Sbjct: 175 LELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGAEVS 234 Query: 263 GFQIVNNENPMVQQFIQRWVRLDEREFPEAKNAPLKYTSALTHDAILVIAEAFRYLRRQR 322 GFQIV+ ++ +V +FI+RW L+E+E+P A A +KYTSALT+DA+ V+ EAFR LR+QR Sbjct: 235 GFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQR 294 Query: 323 VDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNIQFDTYGRRTNYTIDVYEM 382 +++SRRG+AGDCLANPAVPW QG++IERALK VQV+G++GNI+FD G+R NYTI++ E+ Sbjct: 295 IEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMEL 354 Query: 383 KVSGSRKAGYWNEYERFVPFSDQQISNDSSSSENRTIVVTTILESPYVMYKKNHEQLEGN 442 K +G RK GYW+E ++ V +D+S E +T+VVTTILESPYVM KKNHE LEGN Sbjct: 355 KTNGPRKIGYWSEVDKMVVT---LTEDDTSGLEQKTVVVTTILESPYVMMKKNHEMLEGN 411 Query: 443 ERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAP 502 ERYEGYCVDLA EIAKH KYKL+IVGDGKYGARD +TKIWNGMVGELVYG+ADIA+AP Sbjct: 412 ERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAP 471 Query: 503 LTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSV 562 LTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWM IVFAYI VSV Sbjct: 472 LTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMAIVFAYILVSV 531 Query: 563 VLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSLGAFMQQGCDISPRSL 622 VLFLVSRFSPYEWH EE D + + NEFGIFNS WF+L F QQG DISPRSL Sbjct: 532 VLFLVSRFSPYEWH----TEEFEDGE---ESTNEFGIFNSFWFALKLFFQQGADISPRSL 584 Query: 623 SGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTK 682 S RIV GVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDL+KQTEIAYGTLDSGSTK Sbjct: 585 SARIVAGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTK 644 Query: 683 EFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRK 742 EFFRRSKIAV++KMW+YM+SAEPSVF +TTA+GVARVRKSKGK+A+LLESTMNEYIEQRK Sbjct: 645 EFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRK 704 Query: 743 PCDTMKVGGNLDSKGYGVATPKGSALRTPVNLAVLKLSEQGILDKLKNKWWYDKGECGAK 802 PCDTMKVGGNLDSKGYG+ATPKGS+L TPVNLAVLKLSEQG+LDKLKNKWWYDKGECGAK Sbjct: 705 PCDTMKVGGNLDSKGYGIATPKGSSLGTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAK 764 Query: 803 DSGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCYKSRAESKRMK 852 DSGSK+KTSALSLSNVAGVFYILVGGLGLAM+VALIEF YKSRAE+KRMK Sbjct: 765 DSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFAYKSRAEAKRMK 814 >5KUF-A nrPDB Length = 877 Score = 1017 bits (2630), Expect = 0.0, Method: Composition-based stats. Identities = 350/844 (41%), Positives = 507/844 (60%), Gaps = 40/844 (4%) Query: 26 NTISIGGLFMRNTV----QEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFSVT 81 + + GG+F E AFRFAV N N+ T L Y ++ +SF + Sbjct: 3 HVLRFGGIFEYVESGPMGAEELAFRFAVNTINRNR-TLLPNTTLTYDTQKINLYDSFEAS 61 Query: 82 NAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSFP---TDADVQFVIQMRP- 137 C Q S GV AIFG S N + S C AL + + +D F + + P Sbjct: 62 KKACDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLYPD 121 Query: 138 --ALKGAILSLLGYYKWEKFVYLYDTERGFSILQAIMEAAVQNNWQVTARSVGNIKDIQE 195 +L AIL L+ ++KW+ +YD G LQ +++A + N ++ R + D ++ Sbjct: 122 FSSLSRAILDLVQFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLKIRQLP--ADTKD 179 Query: 196 FRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANLGFTDIVLERVM 255 + +++EM R +E + DC E IL+Q + +G + YHY+ L + +E Sbjct: 180 AKPLLKEMKRGKEFHVIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYR 239 Query: 256 HGGANITGFQIVNNENPMVQQFIQRWV--RLDEREFPEAK--NAPLKYTSALTHDAILVI 311 + G N+TGF+I+N EN V I++W RL P++ + + +AL +DA+ V+ Sbjct: 240 YSGVNMTGFRILNTENTQVSSIIEKWSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVV 299 Query: 312 AEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNIQFD-TYG 370 + A + + V S+ C N PW G +K +G+TG I F+ T G Sbjct: 300 SVAVQQFPQMTV------SSLQC--NRHKPWRFGTRFMSLIKEAHWEGLTGRITFNKTNG 351 Query: 371 RRTNYTIDVYEMKVSGSRKAGYWNEYERFVPFSDQQ--ISNDSSSSENRTIVVTTILESP 428 RT++ +DV +K G K G W+ Q+ +N + S NR+++VTTILE P Sbjct: 352 LRTDFDLDVISLKEEGLEKIGTWDPASGLNMTESQKGKPANITDSLSNRSLIVTTILEEP 411 Query: 429 YVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMV 488 YV++KK+ + L GN+R+EGYC+DL E++ + Y++ +V DGKYGA+D WNGMV Sbjct: 412 YVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDGKYGAQDDVNGQWNGMV 471 Query: 489 GELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYE 548 EL+ +AD+AVAPLTIT VRE+VIDFSKPFM+LGISI+ +KP + PGVFSFL+PL+ + Sbjct: 472 RELIDHKADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPD 531 Query: 549 IWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSLG 608 IWM ++ AY+GVSVVLF+++RFSPYEW+ N P +P S N F + NS WF +G Sbjct: 532 IWMYVLLAYLGVSVVLFVIARFSPYEWY----NPHPCNPDSDV-VENNFTLLNSFWFGVG 586 Query: 609 AFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ 668 A MQQG ++ P++LS RIVGG+WWFFTLIIISSYTANLAAFLTVERM SPI+SA+DLAKQ Sbjct: 587 ALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQ 646 Query: 669 TEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAF 728 T+I YG ++ GST FF++SKI+ Y+KMW++M S SV K++ +G+ RV S +A Sbjct: 647 TKIEYGAVEDGSTMTFFKKSKISTYDKMWAFMSSRRQSVLVKSSEEGIQRVLTS--DYAL 704 Query: 729 LLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRTPVNLAVLKLSEQGILDKL 788 L+EST E++ QR C+ ++GG +DSKGYGV TP GS R + +A+L+L E+G L + Sbjct: 705 LMESTTIEFVTQRN-CNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMM 763 Query: 789 KNKWWYDKGECGAKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCYKSRAES 848 K KWW G C ++S + SAL + N+ G+F +L GL L++ VA+ EF YKS+ + Sbjct: 764 KEKWWRGNG-CPEEESK---EASALGVQNIGGIFIVLAAGLVLSVFVAVGEFLYKSKKNA 819 Query: 849 KRMK 852 + K Sbjct: 820 QLEK 823 >5IPR-B nrPDB Length = 825 Score = 771 bits (1991), Expect = 0.0, Method: Composition-based stats. Identities = 204/879 (23%), Positives = 363/879 (41%), Gaps = 140/879 (15%) Query: 33 LFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHL-----------DSSNSFSVT 81 + R Q+H AV L T + K H HL S+ S+ Sbjct: 18 FYSRAYAQKHPNMDIAVILVGTTEEVAIKDVHEKDDFHHLPVTPRVELVTMQESDPKSII 77 Query: 82 NAFCSQFS----RGVY--------AIFGFYDQMSMNTLTSFCGALHTSFVTPSFPTDADV 129 C S +GV AI D +S+ TLT G S + + +A + Sbjct: 78 TRICDLMSDKKVQGVVFGDDTDQEAIAQILDFISVQTLTPILGIHGGSSMIMADKEEASM 137 Query: 130 QFVIQMRPALK---GAILSLLGYYKWEKFVYLYDTERGFSILQAIMEAAVQN---NWQV- 182 F Q P+++ +L+++ Y W F + G+ + + + ++N W++ Sbjct: 138 FF--QFGPSIEQQASVMLNIMEEYDWYIFSIVTTYFPGYQDFENKVRSTIENSFVGWELE 195 Query: 183 -TARSVGNIKDIQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYML 241 ++ DI +I ++ + Q L+ C E I E +G G+ +++ Sbjct: 196 EVIHLDMSLDDIDS--KIQNQLKKLQSPVILLYCTKEEATYIFEVAHSVGLTGYGFTWIV 253 Query: 242 ANL--GFTDIVLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNAPLKY 299 +L G TD V + G +++ DE ++ + P Sbjct: 254 PSLVAGDTDTVPDEFPTGLISVS---------------------YDEWDY----DLP--- 285 Query: 300 TSALTHDAILVIAEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQG 359 A D I +I A + + + + S+ + + V + ++R L V +G Sbjct: 286 --ARVRDGIAIITTAASTMLSEHNSIPQSKSSCNNIQESRV--YEAHMLKRYLINVTFEG 341 Query: 360 MTGNIQFDTYGRRTNYTIDVYEMKVSGSRKAGYWNEYERFVPFSDQQISNDSSSSENRTI 419 + D Y I + + R Y + + P D +++ E + Sbjct: 342 RDLSFSEDGYQMHPKLVIILLNQERKWERVGKYKDRSLKMWPVFDLYPNSEEHKDE--HL 399 Query: 420 VVTTILESPYVMY---------------------KKNHEQLEGNE----RYEGYCVDLAY 454 + T+ E+P+V+ + + EG +G+C+D+ Sbjct: 400 SIVTLEEAPFVIVEDVDPLSGTCMRNTVPCRKQIRPENRTEEGGNYIKRCCKGFCIDILK 459 Query: 455 EIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVID 514 +IAK V+ Y L +V +GK+G + +WNGM+GE+V RA +AV LTI R EV+D Sbjct: 460 KIAKTVKFTYDLYLVTNGKHGKK--INGVWNGMIGEVVTKRAYMAVGSLTINEERSEVVD 517 Query: 515 FSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW-MCIVFAYIGVSVVLFLVSRFSPY 573 FS PF+ GIS+M+ + + +FL+P + ++W M V I +V +F+ FSP Sbjct: 518 FSVPFIETGISVMVSRSNGTVSPS-AFLEPFSADVWVMMFVMLLIVSAVAVFVFEYFSPV 576 Query: 574 EWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSLGAFMQQGCDI-SPRSLSGRIVGGVWW 632 ++ F I ++W G + +P+ + +I+ VW Sbjct: 577 GYN-----------------GPSFTIGKAIWLLWGLVFNNSLPVQNPKGTTSKIMVSVWA 619 Query: 633 FFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTE------IAYGTLDSGSTKEFFR 686 FF +I ++SYTANLAAF+ R V + D Q +GT+ +GST+ R Sbjct: 620 FFAVIFLASYTANLAAFMIQRRYVDQVSGLSDKKFQRPNDFSPAFRFGTVPNGSTERNIR 679 Query: 687 RSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQR-KPCD 745 + Y +M SYM F + + KS AF+ ++ + Y+ R + C Sbjct: 680 NN----YLEMHSYMVK-----FNQRSVQDALLSLKSGKLDAFIYDAAVLNYMAGRDEGCK 730 Query: 746 TMKVGGN--LDSKGYGVATPKGSALRTPVNLAVLKLSEQGILDKLKNKWWYDKGECGAKD 803 + +G + GYG+A K S + V+LA+L+L G +++L+ W G C + Sbjct: 731 LVTIGSGKVFATTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEELEALWL--TGIC--HN 786 Query: 804 SGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCY 842 ++ +S L + N+AGVFY+L + L+++ ++E + Sbjct: 787 EKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIMEHLF 825 >4PE5-B nrPDB Length = 820 Score = 706 bits (1822), Expect = 0.0, Method: Composition-based stats. Identities = 195/872 (22%), Positives = 353/872 (40%), Gaps = 130/872 (14%) Query: 38 TVQEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHL-----------DSSNSFSVTNAFCS 86 + + + AV L T+ K H HL + ++ S+ C Sbjct: 2 SQKSPPSIGIAVILVGTSDEVAIKDAHEKDDFHHLSVVPRVELVAMNETDPKSIITRICD 61 Query: 87 QFS----RGVY--------AIFGFYDQMSMNTLTSFCGALHTSFVTPSFPTDADVQFVIQ 134 S +GV AI D +S TLT G S + + ++ + F Q Sbjct: 62 LMSDRKIQGVVFADDTDQEAIAQILDFISAQTLTPILGIHGGSSMIMADKDESSMFF--Q 119 Query: 135 MRPALK---GAILSLLGYYKWEKFVYLYDTERGFSILQAIMEAAVQN---NWQVTARSVG 188 P+++ +L+++ Y W F + G+ + + ++N W++ + Sbjct: 120 FGPSIEQQASVMLNIMEEYDWYIFSIVTTYFPGYQDFVNKIRSTIENSFVGWELEEVLLL 179 Query: 189 NIKDIQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANL--GF 246 ++ +I ++ + Q L+ C E I E +G GY +++ +L G Sbjct: 180 DMSLDDGDCKIQNQLKKLQSPIILLYCTKEEATYIFEVANSVGLTGYGYTWIVPSLVAGD 239 Query: 247 TDIVLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNAPLKYTSALTHD 306 TD V G +++ DE ++ A D Sbjct: 240 TDTVPSEFPTGLISVS---------------------YDEWDYGLP---------ARVRD 269 Query: 307 AILVIAEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNIQF 366 I +I A + + + S+ + Q + R L V +G + Sbjct: 270 GIAIITTAASDMLSEHSFIPEPKSSCYNTHEKRI--YQSNMLNRYLINVTFEGRDLSFSE 327 Query: 367 DTYGRRTNYTIDVYEMKVSGSRKAGYWNEYERFVPFSDQQISNDSSSSENRTIVVTTILE 426 D Y I + + R + ++ + + +++ + + T+ E Sbjct: 328 DGYQMHPKLVIILLNKERKWERVGKWKDKSLQM-----KYYVWP-RMTQDDHLSIVTLEE 381 Query: 427 SPYVMY-------------------------KKNHEQLEGNERYEGYCVDLAYEIAKHVR 461 +P+V+ K + E + +G+C+D+ +I+K V+ Sbjct: 382 APFVIVESVDPLSGTCMRNTVPCQKRIISENKTDEEPGYIKKCCKGFCIDILKKISKSVK 441 Query: 462 IKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMS 521 Y L +V +GK+G + WNGM+GE+V RA +AV LTI R EV+DFS PF+ Sbjct: 442 FTYDLYLVTNGKHGKK--INGTWNGMIGEVVMKRAYMAVGSLTINEERSEVVDFSVPFIE 499 Query: 522 LGISIMIKKPQKSKPGVFSFLDPLAYEIW-MCIVFAYIGVSVVLFLVSRFSPYEWHLEDN 580 GIS+M+ + + +FL+P + +W M V I +V +F+ FSP ++ + Sbjct: 500 TGISVMVSRSNGTVSPS-AFLEPFSACVWVMMFVMLLIVSAVAVFVFEYFSPVGYN--RS 556 Query: 581 NEEPRDPQSPPDPPNEFGIFNSLWFSLGAFMQQGCDI-SPRSLSGRIVGGVWWFFTLIII 639 + R+P P F I ++W G + +P+ + +I+ VW FF +I + Sbjct: 557 LADGREPGGP-----SFTIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFL 611 Query: 640 SSYTANLAAFLTVERMVSPIESAEDLAKQ------TEIAYGTLDSGSTKEFFRRSKIAVY 693 +SYTANLAAF+ E V + D Q +GT+ +GST+ R + Y Sbjct: 612 ASYTANLAAFMIQEEYVDQVSGLSDKKFQRPNDFSPPFRFGTVPNGSTERNIRNN----Y 667 Query: 694 EKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQR-KPCDTMKVGGN 752 +M +YM F + D K+ AF+ ++ + Y+ R + C + +G Sbjct: 668 AEMHAYMGK-----FNQRGVDDALLSLKTGKLDAFIYDAAVLNYMAGRDEGCKLVTIGSG 722 Query: 753 --LDSKGYGVATPKGSALRTPVNLAVLKLSEQGILDKLKNKWWYDKGECGAKDSGSKDKT 810 S GYG+A K S + V+LA+L+L G +++L+ W G C + ++ + Sbjct: 723 KVFASTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEELEALWL--TGIC--HNEKNEVMS 778 Query: 811 SALSLSNVAGVFYILVGGLGLAMMVALIEFCY 842 S L N+AGVFY+L + L+++ + E + Sbjct: 779 SQLDCDNMAGVFYMLGAAMALSLITFISEHLF 810 >6IRA-D nrPDB Length = 853 Score = 650 bits (1677), Expect = 0.0, Method: Composition-based stats. Identities = 188/856 (21%), Positives = 350/856 (40%), Gaps = 120/856 (14%) Query: 56 QNTTEKPFHLNYHVDHLDSSNSFSVTNAFCSQFS----RGVY--------AIFGFYDQMS 103 + P +N ++ ++ S+ C S G+ A+ D +S Sbjct: 58 EQAAGLPLDVNVVALLMNRTDPKSLITHVCDLMSGARIHGLVFGDDTDQEAVAQMLDFIS 117 Query: 104 MNTLTSFCGALHTSFVTPSFPTDADVQFVIQMRPALKG---AILSLLGYYKWEKFVYLYD 160 +T G + + + F Q +++ +L ++ Y W F + Sbjct: 118 SHTFVPILGIHGGASMIMADKDPTSTFF--QFGASIQQQATVMLKIMQDYDWHVFSLVTT 175 Query: 161 TERGFSILQAIMEAAVQN---NWQVTARSVGNIKDIQEFRRIIEEMDRRQEKRYLIDCEV 217 G+ + ++ V N W + ++V + E + ++ + L+ C Sbjct: 176 IFPGYREFISFVKTTVDNSFVGWDM--QNVITLDTSFEDAKTQVQLKKIHSSVILLYCSK 233 Query: 218 ERINTILEQVVILGKHSRGYHYMLANL--GFTDIVLERVMHGGANITGFQIVNNENPMVQ 275 + IL + LG + +++ +L G T+++ + G +++ Sbjct: 234 DEAVLILSEARSLGLTGYDFFWIVPSLVSGNTELIPKEFPSGLISVS------------- 280 Query: 276 QFIQRWVRLDEREFPEAKNAPLKYTSALTHDAILVIAEAFRYLRRQRVDVSRRGSAGDCL 335 D+ ++ A D I ++ A + + + ++ C Sbjct: 281 --------YDDWDYSL---------EARVRDGIGILTTAASSMLEKFSYIPEAKAS--CY 321 Query: 336 ANPAVPWSQGIDIERALKMVQVQGMTGNIQFDTYGRRTNYTIDVYEMKVSGSRKAGYWNE 395 P + + V G + + Y + V K G W Sbjct: 322 GQMERPEVPMHTLHPFMVNVTWDGKDLSFTEEGYQVHPRLVVIVLNKDREW-EKVGKWEN 380 Query: 396 YE---RFVPFSDQQISNDSSSSENRTIVVTTILESPYV---------------------M 431 + R + + +D +N + + T+ E+P+V Sbjct: 381 HTLSLRHAVWPRYKSFSDCEPDDNH-LSIVTLEEAPFVIVEDIDPLTETCVRNTVPCRKF 439 Query: 432 YKKNHEQLEG---NERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMV 488 K N+ EG + +G+C+D+ ++++ V+ Y L +V +GK+G + +WNGM+ Sbjct: 440 VKINNSTNEGMNVKKCCKGFCIDILKKLSRTVKFTYDLYLVTNGKHGKK--VNNVWNGMI 497 Query: 489 GELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYE 548 GE+VY RA +AV LTI R EV+DFS PF+ GIS+M+ + + +FL+P + Sbjct: 498 GEVVYQRAVMAVGSLTINEERSEVVDFSVPFVETGISVMVSRSNGTVSPS-AFLEPFSAS 556 Query: 549 IW-MCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSL 607 +W M V I ++ +F+ FSP ++ N + + P P F I ++W Sbjct: 557 VWVMMFVMLLIVSAIAVFVFEYFSPVGYN--RNLAKGKAPHGP-----SFTIGKAIWLLW 609 Query: 608 GAFMQQGCDI-SPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLA 666 G + +P+ + +I+ VW FF +I ++SYTANLAAF+ R V + D Sbjct: 610 GLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQRRFVDQVTGLSDKK 669 Query: 667 KQ------TEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVR 720 Q +GT+ +GST+ R + Y M YM K D + ++ Sbjct: 670 FQRPHDYSPPFRFGTVPNGSTERNIRNN----YPYMHQYMTKFNQ----KGVEDALVSLK 721 Query: 721 KSKGKFAFLLESTMNEYIEQR-KPCDTMKVGGN--LDSKGYGVATPKGSALRTPVNLAVL 777 K AF+ ++ + Y R + C + +G + GYG+A KGS + ++LA+L Sbjct: 722 TGK-LDAFIYDAAVLNYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGSPWKRQIDLALL 780 Query: 778 KLSEQGILDKLKNKWWYDKGECGAKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMMVAL 837 + G +++L+ W G C + ++ +S L + N+AGVFY+L + L+++ + Sbjct: 781 QFVGDGEMEELETLWL--TGIC--HNEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFI 836 Query: 838 IEF-CYKSRAESKRMK 852 E YKSRAE+KRMK Sbjct: 837 WEHLFYKSRAEAKRMK 852 >5UP2-B nrPDB Length = 831 Score = 646 bits (1665), Expect = 0.0, Method: Composition-based stats. Identities = 197/909 (21%), Positives = 357/909 (39%), Gaps = 147/909 (16%) Query: 1 MGQSVLRAVFFLVLGLLGHSHGGFPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTE 60 MG VL FL G LGH + AV L + TE Sbjct: 1 MGMFVLLLYTFLYAGDLGH-----------------GAEKSFPVLNIAVIL-GRTRYITE 42 Query: 61 KPFH--------LNYHVDHL----DSSNSFSVTNAFCSQFS----RGVY--------AIF 96 + L++ V+ + ++ S+ C S GV AI Sbjct: 43 RDIRSLWTRDMSLDFDVNVVTLLVQQTDPKSIITHVCDLMSGTKIHGVVFGDDTDQEAIA 102 Query: 97 GFYDQMSMNTLTSFCGALHTSFVTPSFPTDADVQFVIQMRPALKG---AILSLLGYYKWE 153 D +S T G S + + + F Q ++K +L+++ Y W Sbjct: 103 QILDFVSSQTFIPILGIHGGSSMIMADKDEMSTFF--QFGASIKQQATVMLNIMEEYDWH 160 Query: 154 KFVYLYDTERGFSILQAIMEAAVQN---NWQVTARSVGNIKDIQEFRRIIEEMDRRQEKR 210 F + G+ + ++ V N W+V ++ + + + ++ + Sbjct: 161 VFSVITSNFPGYRDFISFIKTTVDNSFVGWEV--QNYITLDTSYTDAQTLTQLKKIHSSV 218 Query: 211 YLIDCEVERINTILEQVVILGKHSRGYHYMLANL--GFTDIVLERVMHGGANITGFQIVN 268 L+ C + I E+ LG G+ +++ +L G TDI+ G +++ Sbjct: 219 ILLYCSKDEATYIFEEARSLGLMGYGFVWIVPSLVTGNTDIIPYEFPSGLVSVS------ 272 Query: 269 NENPMVQQFIQRWVRLDEREFPEAKNAPLKYTSALTHDAILVIAEAFRYLRRQRVDVSRR 328 D+ ++ A D + +I A + + + Sbjct: 273 ---------------YDDWDYGI---------EARVRDGLGIITTAASAMLEKHSVIPEA 308 Query: 329 GSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNIQFDTYGRRTNYTIDVYEMKVSGSR 388 ++ P + + V G + D Y + + M+ Sbjct: 309 KTSCYGQNERNDPPL--HTLHNFMINVTWDGKDLSFTEDGYQANPKLVVLLLNMEREW-E 365 Query: 389 KAGYWNEYERFVPFSDQQISNDSSSSENRTIVVTTILESPYV------------------ 430 K G W E + DS +N + + T+ E+P+V Sbjct: 366 KVGKW-EAKSLNMKYPVWPRIDSDHDDNH-LSIVTLEEAPFVIVENIDYLTGTCVRNTVP 423 Query: 431 ---MYKKNHEQLEG---NERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIW 484 ++ + EG + +G+C+D+ +++K V+ Y L +V +GK+G + +W Sbjct: 424 CRKYFRLANSTTEGTSVKKCCKGFCIDILKKLSKTVKFTYDLYLVTNGKHGKKIK--NVW 481 Query: 485 NGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDP 544 NGM+GE+VY RA +AV LTI R +DFS PF+ GIS+M+ + + +FL+P Sbjct: 482 NGMIGEVVYKRAVMAVGSLTINEERSVAVDFSVPFVETGISVMVSRSAGTVSPS-AFLEP 540 Query: 545 LAYEIW-MCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSL 603 + +W M V + ++ +F+ FSP ++ N + +DP P F I ++ Sbjct: 541 FSASVWVMMFVMLLLVSAMAVFIFEYFSPVGYN--RNLAQGKDPHGP-----SFTIGKAV 593 Query: 604 WFSLGAFMQQGCDI-SPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESA 662 W G + +P+ + +I+ +W FF +I ++SYTANLAAF+ R V + Sbjct: 594 WLLWGLVFNNSLPVQNPKGTTSKIIVSIWAFFAVIFLASYTANLAAFMIQRRFVDQVTGL 653 Query: 663 EDLAKQ------TEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGV 716 D Q +GT+ GST+ R + Y M YM K D + Sbjct: 654 SDNKFQRPHDYSPPFRFGTVPQGSTERNIRNN----YPDMHQYMVKFHQ----KGVQDAL 705 Query: 717 ARVRKSKGKFAFLLESTMNEYIEQR-KPCDTMKVGGN--LDSKGYGVATPKGSALRTPVN 773 ++ K AF+ ++ + Y+ R + C + +G + GYG+A KGS + P++ Sbjct: 706 VSLKTGK-LDAFIYDAAVLNYMAGRDEGCKLVTIGSGYIFATTGYGIALQKGSRWKRPID 764 Query: 774 LAVLKLSEQGILDKLKNKWWYDKGECGAKDSGSKDKTSALSLSNVAGVFYILVGGLGLAM 833 LA+L+ G +++L+ W G C ++ +S L + N+AGVFY+L + L++ Sbjct: 765 LALLQFVGDGEMEELEKLWL--TGIC--HTEKNEVMSSQLDIDNMAGVFYMLAAAMALSL 820 Query: 834 MVALIEFCY 842 + + E + Sbjct: 821 ITFVWEHLF 829 >5UOW-A nrPDB Length = 814 Score = 624 bits (1609), Expect = e-179, Method: Composition-based stats. Identities = 202/877 (23%), Positives = 365/877 (41%), Gaps = 122/877 (13%) Query: 25 PNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFSVTNAF 84 P ++IG + +T + FR AV N ++ T K V H N+ + + Sbjct: 2 PKIVNIGAVL--STKKHEQIFREAVNQANK-RHFTRKIQLNATSVTH--RPNAIQMALSV 56 Query: 85 C-SQFSRGVYAIF-----GFYDQMSMNTLTSFCGALHTSFV----TPSFPTDADV--QFV 132 C S VYAI D ++ ++ G + S +D + F+ Sbjct: 57 CEDLISSQVYAILVSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFL 116 Query: 133 IQMRPALKGAIL--SLLGYYKWEKFVYLYDTERGFSILQAIMEAAVQNNWQVTARSVGNI 190 + P A++ ++ + W + + + Q +E ++ + + Sbjct: 117 RTVPPYSHQALVWFEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEEKESKADKVLQFE 176 Query: 191 KDIQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANLGFTDIV 250 + ++ E + + ++ + + + +L GY +++ G +I Sbjct: 177 PGTKNLTALLLEAKELEARVIILSASEDDATAVYKSAAMLDMTGAGYVWLV---GEREIS 233 Query: 251 LERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNAPLKYTSALTHDAILV 310 + + I G Q++N K SA DA+ V Sbjct: 234 GSALRYAPDGIIGLQLING----------------------------KNESAHISDAVAV 265 Query: 311 IAEAFRYL-RRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQV-QGMTGNIQFDT 368 +A+A L +++ RG C+ N + W G +R L + G+TG I+F+ Sbjct: 266 VAQAIHELFEMEQITDPPRG----CVGNTNI-WKTGPLFKRVLMSSKYPDGVTGRIEFNE 320 Query: 369 YGRRTNYTIDVYEMKVS-----GSRKAGYWNEYERFVPFSDQQISNDSSSSENRTIVVTT 423 G R + ++ G Y + +R + + + + + + T Sbjct: 321 DGDRKFAQYSIMNLQNRKLVQVGIFDGSYIIQNDRKIIWPGGETERPQGYQMSTRLKIVT 380 Query: 424 ILESPYVMYKKNHEQLEGNERYE-----------------------------GYCVDLAY 454 I + P+V + E Y G+CVDL Sbjct: 381 IHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPDETIPGRPTVPQCCYGFCVDLLI 440 Query: 455 EIAKHVRIKYKLSIVGDGKYGAR----DPETKIWNGMVGELVYGRADIAVAPLTITLVRE 510 ++A+ + Y++ +V DGK+G + + WNGM+GEL+ G+AD+ VAPLTI R Sbjct: 441 KLAREMDFTYEVHLVADGKFGTQERVNNSNAAAWNGMMGELLSGQADMIVAPLTINNERA 500 Query: 511 EVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRF 570 + I+FSKPF G++I++KK + + SF+ P +W+ + + V+V+L+L+ RF Sbjct: 501 QYIEFSKPFKYQGLTILVKKE-IPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYLLDRF 559 Query: 571 SPYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSLGAFMQQGC-DISPRSLSGRIVGG 629 SP+ ++ D + +++WFS + G + +PRS S RI+G Sbjct: 560 SPFGRFKVNSAAAEED---------ALTLSSAMWFSWRVLLNSGLGEGAPRSFSARILGM 610 Query: 630 VWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQT---EIAYGTLDSGSTKEFFR 686 VW F +II++SYTANLAAFL + R I D + + Y T+ S +FR Sbjct: 611 VWALFAMIIVASYTANLAAFLVLRRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFR 670 Query: 687 RSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDT 746 R M+ +M+ ++ A+ + VR +K AF+ +S + E+ E + CD Sbjct: 671 RQ--VELSTMYRHMEKHN----YESAAEAIQAVRDNK-LHAFIWDSAVLEF-EASQDCDL 722 Query: 747 MKVGGNLDSKGYGVATPKGSALRTPVNLAVLKLSEQGILDKLKNKWWYDKGECGAKDSGS 806 + G G+G+ K S + V+L +LK E G +++L +K W EC ++ + Sbjct: 723 VTTGELFFRSGFGIGMRKDSPWKQEVSLNILKSHENGFMEEL-DKTWVRYQECDSRSNAP 781 Query: 807 KDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCYK 843 + L+ N+AGVFY++ GG+ + + IE YK Sbjct: 782 ----ATLTFENMAGVFYLVAGGIVAGIFLIFIEIAYK 814 >5KUH-A nrPDB Length = 757 Score = 622 bits (1603), Expect = e-178, Method: Composition-based stats. Identities = 192/578 (33%), Positives = 296/578 (51%), Gaps = 35/578 (6%) Query: 26 NTISIGGLFMRNTV----QEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFSVT 81 + + GG+F E AFRFAV N N+ T L Y ++ +SF + Sbjct: 3 HVLRFGGIFEYVESGPMGAEELAFRFAVNTINRNR-TLLPNTTLTYDTQKINLYDSFEAS 61 Query: 82 NAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSFP---TDADVQFVIQMRP- 137 C Q S GV AIFG S N + S C AL + + +D F + + P Sbjct: 62 KKACDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLYPD 121 Query: 138 --ALKGAILSLLGYYKWEKFVYLYDTERGFSILQAIMEAAVQNNWQVTARSVGNIKDIQE 195 +L AIL L+ ++KW+ +YD G LQ +++A + N ++ R + D ++ Sbjct: 122 FSSLSRAILDLVQFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLKIRQLP--ADTKD 179 Query: 196 FRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANLGFTDIVLERVM 255 + +++EM R +E + DC E IL+Q + +G + YHY+ L + +E Sbjct: 180 AKPLLKEMKRGKEFHVIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYR 239 Query: 256 HGGANITGFQIVNNENPMVQQFIQRWV--RLDEREFPEAK--NAPLKYTSALTHDAILVI 311 + G N+TGF+I+N EN V I++W RL P++ + + +AL +DA+ V+ Sbjct: 240 YSGVNMTGFRILNTENTQVSSIIEKWSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVV 299 Query: 312 AEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNIQFD-TYG 370 + A + + V S+ C N PW G +K +G+TG I F+ T G Sbjct: 300 SVAVQQFPQMTV------SSLQC--NRHKPWRFGTRFMSLIKEAHWEGLTGRITFNKTNG 351 Query: 371 RRTNYTIDVYEMKVSGSRKAGYWNEYERFVPFSDQQ--ISNDSSSSENRTIVVTTILESP 428 RT++ +DV +K G K G W+ Q+ +N + S NR+++VTTILE P Sbjct: 352 LRTDFDLDVISLKEEGLEKIGTWDPASGLNMTESQKGKPANITDSLSNRSLIVTTILEEP 411 Query: 429 YVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMV 488 YV++KK+ + L GN+R+EGYC+DL E++ + Y++ +V DGKYGA+D WNGMV Sbjct: 412 YVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDGKYGAQDDVNGQWNGMV 471 Query: 489 GELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYE 548 EL+ +AD+AVAPLTIT VRE+VIDFSKPFM+LGISI+ +K D LA + Sbjct: 472 RELIDHKADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKGTP-----IDSADDLAKQ 526 Query: 549 IWMCIVFAYIGVSVVLFLVSRFSPYE--WHLEDNNEEP 584 + G ++ F S+ S Y+ W + + Sbjct: 527 TKIEYGAVEDGSTMTFFKKSKISTYDKMWAFMSSRRQS 564 Score = 268 bits (686), Expect = 5e-72, Method: Composition-based stats. Identities = 89/202 (44%), Positives = 133/202 (65%), Gaps = 7/202 (3%) Query: 651 TVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTK 710 + R +PI+SA+DLAKQT+I YG ++ GST FF++SKI+ Y+KMW++M S SV K Sbjct: 509 ILYRKGTPIDSADDLAKQTKIEYGAVEDGSTMTFFKKSKISTYDKMWAFMSSRRQSVLVK 568 Query: 711 TTADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRT 770 ++ +G+ RV S +A L+EST E++ QR C+ ++GG +DSKGYGV TP GS R Sbjct: 569 SSEEGIQRVLTS--DYALLMESTTIEFVTQRN-CNLTQIGGLIDSKGYGVGTPMGSPYRD 625 Query: 771 PVNLAVLKLSEQGILDKLKNKWWYDKGECGAKDSGSKDKTSALSLSNVAGVFYILVGGLG 830 + +A+L+L E+G L +K KWW G C ++S + SAL + N+ G+F +L GL Sbjct: 626 KITIAILQLQEEGKLHMMKEKWWRGNG-CPEEESK---EASALGVQNIGGIFIVLAAGLV 681 Query: 831 LAMMVALIEFCYKSRAESKRMK 852 L++ VA+ EF YKS+ ++ K Sbjct: 682 LSVFVAVGEFLYKSKKNAQLEK 703 >5FXI-A nrPDB Length = 846 Score = 617 bits (1590), Expect = e-177, Method: Composition-based stats. Identities = 200/905 (22%), Positives = 363/905 (40%), Gaps = 145/905 (16%) Query: 25 PNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFSVTNAF 84 P ++IG + +T + FR AV N + + N+ + + Sbjct: 2 PKIVNIGAVL--STRKHEQMFREAVNQANKRHGSWKIQLQATSVTHK---PNAIQMALSV 56 Query: 85 C-SQFSRGVYAIF-----GFYDQMSMNTLTSFCGALHTSFV--TPSFPTDADVQFVIQM- 135 C S VYAI D + ++ G + T +D + Sbjct: 57 CEDLISSQVYAILVSHPPTPNDHFTPTPVSYTAGFYRIPVLGLTTRMSIYSDKSIHLSFL 116 Query: 136 -----RPALKGAILSLLGYYKWEKFVYLYDTERGFSILQAIMEAAVQ-NNWQVTARSVGN 189 ++ Y W + L + Q +E ++ + R+ N Sbjct: 117 RTVPPYSHQSSVWFEMMRVYNWNHIILLVSDDHEGRAAQKRLETLLEERESKSKKRNYEN 176 Query: 190 IKD--------------------IQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVI 229 + + ++ E + + ++ + T+ + Sbjct: 177 LDQLSYDNKRGPKAEKVLQFDPGTKNVTALLMEARELEARVIILSASEDDAATVYRAAAM 236 Query: 230 LGKHSRGYHYMLANLGFTDIVLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREF 289 L GY +++ G +I + + I G Q++N Sbjct: 237 LDMTGSGYVWLV---GEREISGNALRYAPDGIIGLQLING-------------------- 273 Query: 290 PEAKNAPLKYTSALTHDAILVIAEAFRYL-RRQRVDVSRRGSAGDCLANPAVPWSQGIDI 348 K SA DA+ V+A+A L ++ + RG C+ N + W G Sbjct: 274 --------KNESAHISDAVGVVAQAVHELLEKENITDPPRG----CVGNTNI-WKTGPLF 320 Query: 349 ERALKMVQV-QGMTGNIQFDTYGRRTNYTIDVYEMKVSGSRKAGYWN-----EYERFVPF 402 +R L + G+TG ++F+ G R + ++ + G +N +R + + Sbjct: 321 KRVLMSSKYADGVTGRVEFNEDGDRKFAQYSIMNLQNRKLVQVGIYNGTHVIPNDRKIIW 380 Query: 403 SDQQISNDSSSSENRTIVVTTILESPYVMYKKNHEQLEGNERYE---------------- 446 + + + + TI + P+V K E + Sbjct: 381 PGGETEKPRGYQMSTRLKIVTIHQEPFVYVKPTMSDGTCKEEFTVNGDPVKKVICTGPND 440 Query: 447 ---------------GYCVDLAYEIAKHVRIKYKLSIVGDGKYGAR----DPETKIWNGM 487 G+C+DL ++A+ ++ Y++ +V DGK+G + + K WNGM Sbjct: 441 TSPGSPRHTVPQCCYGFCIDLLIKLARTMQFTYEVHLVADGKFGTQERVQNSNKKEWNGM 500 Query: 488 VGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAY 547 +GEL+ G+AD+ VAPLTI R + I+FSKPF G++I++KK + + SF+ P Sbjct: 501 MGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKE-IPRSTLDSFMQPFQS 559 Query: 548 EIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSL 607 +W+ + + V+V+L+L+ RFSP+ ++ E D + +++WFS Sbjct: 560 TLWLLVGLSVHVVAVMLYLLDRFSPFGRFKVNSQSESTD---------ALTLSSAMWFSW 610 Query: 608 GAFMQQGC-DISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLA 666 G + G + +PRS S RI+G VW F +II++SYTANLAAFL ++R I D Sbjct: 611 GVLLNSGIGEGAPRSFSARILGMVWAGFAMIIVASYTANLAAFLVLDRPEERITGINDPR 670 Query: 667 KQT---EIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSK 723 + + Y T+ S +FRR M+ +M+ ++ A+ + VR +K Sbjct: 671 LRNPSDKFIYATVKQSSVDIYFRRQ--VELSTMYRHMEKHN----YESAAEAIQAVRDNK 724 Query: 724 GKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRTPVNLAVLKLSEQG 783 AF+ +S + E+ E + CD + G G+G+ K S + V+L++LK E G Sbjct: 725 -LHAFIWDSAVLEF-EASQKCDLVTTGELFFRSGFGIGMRKDSPWKQQVSLSILKSHENG 782 Query: 784 ILDKLKNKWWYDKGECGAKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCYK 843 ++ L +K W EC ++ + + L+ N+AGVF ++ GG+ + + IE YK Sbjct: 783 FMEDL-DKTWVRYQECDSRSNAP----ATLTCENMAGVFMLVAGGIVAGIFLIFIEIAYK 837 Query: 844 SRAES 848 ++ Sbjct: 838 RHKDA 842 >5L2E-A nrPDB Length = 688 Score = 527 bits (1358), Expect = e-150, Method: Composition-based stats. Identities = 137/589 (23%), Positives = 260/589 (44%), Gaps = 55/589 (9%) Query: 23 GFPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFSVTN 82 G + I IG +F + ++ FR AV N N+ + + + V +D +N F Sbjct: 1 GSDSIIHIGAIFDESAKKDDEVFRTAVGDLNQNEEILQTE-KITFSVTFVDGNNPFQAVQ 59 Query: 83 AFCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFV-----TPSFP--------TDADV 129 C ++G+ A+ S +L S A+H + T P ++ + Sbjct: 60 EACELMNQGILALVSSIGCTSAGSLQSLADAMHIPHLFIQRSTAGTPRSGCGLTRSNRND 119 Query: 130 QFVIQMRPA--LKGAILSLLGYYKWEKFVYLYDTERGFSILQAIMEAAVQNNWQVTARSV 187 + + +RP L IL ++ Y W+KF+ YD+E +Q ++ Q V + V Sbjct: 120 DYTLSVRPPVYLNEVILRVVTEYAWQKFIIFYDSEYDIRGIQEFLDKVSQQGMDVALQKV 179 Query: 188 GN-----IKDIQEFRRIIEEMDRRQE--KRYLIDCEVERINTILEQVVILGKHSRGYHYM 240 N I + + RI EE++R ++ +R ++ + + +VV + H++ Sbjct: 180 ENNINKMITTLFDTMRI-EELNRYRDTLRRAILVMNPATAKSFISEVVETNLVAFDCHWI 238 Query: 241 LANLGFTDIVLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDER--------EFPEA 292 + N D+ ++ ++ +I I+ P+ Q QR R + R + P A Sbjct: 239 IINEEINDVDVQELVR--RSIGRLTIIRQTFPVPQNISQRCFRGNHRISSTLCDPKDPFA 296 Query: 293 KNAPLKYTSALTHDAILVIAEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERAL 352 +N ++ ++ +D +L++A AF + R S ++ C+ + PW G + + Sbjct: 297 QN--MEISNLYIYDTVLLLANAFHKKLQDRKWHSM--ASLSCIRKNSKPWQGGRSMLETI 352 Query: 353 KMVQVQGMTGNIQFDTYGRRTNYTIDVY-----EMKVSGSRKAGYWNEYERFV-PFSDQQ 406 K V G+TG+++F G N ++ E G RK G WN +D++ Sbjct: 353 KKGGVNGLTGDLEFGENGGNPNVHFEILGTNYGEELGRGVRKLGCWNPVTGLNGSLTDKK 412 Query: 407 ISNDSSSSENRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKL 466 + N+ + V T+LE P+VM +N L ++Y+G+ +D+ ++ ++ Y++ Sbjct: 413 LENNMRGVV---LRVVTVLEEPFVMVSEN--VLGKPKKYQGFSIDVLDALSNYLGFNYEI 467 Query: 467 SIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISI 526 + D KYG+ E WNG+VGELV+ RADI ++ LTIT RE V+DF+ +M + + Sbjct: 468 YVAPDHKYGSPQ-EDGTWNGLVGELVFKRADIGISALTITPDRENVVDFTTRYMDYSVGV 526 Query: 527 MIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEW 575 ++++ L L+ + + + +P+E Sbjct: 527 LLRRG-----TSIQSLQDLSKQTDIPYGTVLDSAVYQHVRMKGLNPFER 570 Score = 171 bits (434), Expect = 9e-43, Method: Composition-based stats. Identities = 47/158 (29%), Positives = 81/158 (51%), Gaps = 10/158 (6%) Query: 651 TVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRS------KIAVYEKMWSYMKSAE 704 + R + I+S +DL+KQT+I YGT+ + + R + ++Y +MW + + Sbjct: 526 VLLRRGTSIQSLQDLSKQTDIPYGTVLDSAVYQHVRMKGLNPFERDSMYSQMWRMINRSN 585 Query: 705 PSVFTKTTADGVARVRKSK-GKFAFLLESTMNEYIEQRKP-CDTMKVGGNLDSKGYGVAT 762 S + A ++K K G +AF+ ++ + EY+ P C VG + +GYG+A Sbjct: 586 GS--ENNVLESQAGIQKVKYGNYAFVWDAAVLEYVAINDPDCSFYTVGNTVADRGYGIAL 643 Query: 763 PKGSALRTPVNLAVLKLSEQGILDKLKNKWWYDKGECG 800 GS R + +L+L + G +D LK+KWW G+C Sbjct: 644 QHGSPYRDVFSQRILELQQSGDMDILKHKWWPKNGQCD 681 >5UN1-G nrPDB Length = 451 Score = 483 bits (1244), Expect = e-136, Method: Composition-based stats. Identities = 141/475 (29%), Positives = 232/475 (48%), Gaps = 68/475 (14%) Query: 415 ENRTIVVTTILESPYVMYKKNHEQLEGNERYE---------------------------- 446 + + + TI + P+V + E Y Sbjct: 1 MSTRLKIVTIHQEPFVYVRPTTSDGTCREEYTINGDPIKKVICNGPDETIPGRPTVPQCC 60 Query: 447 -GYCVDLAYEIAKHVRIKYKLSIVGDGKYGAR----DPETKIWNGMVGELVYGRADIAVA 501 G+CVDL ++A+ + Y++ +V DGK+G + + WNGM+GEL+ G+AD+ VA Sbjct: 61 YGFCVDLLIKLAREMDFTYEVHLVADGKFGTQERVNNSNAAAWNGMMGELLSGQADMIVA 120 Query: 502 PLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVS 561 PLTI R + I+FSKPF G++I++KK + + SF+ P +W+ + + V+ Sbjct: 121 PLTINNERAQYIEFSKPFKYQGLTILVKKE-IPRSTLDSFMQPFQSTLWLLVGLSVHVVA 179 Query: 562 VVLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSLGAFMQQGC-DISPR 620 V+L+L+ RFSP+ + + +++WFS + G + +PR Sbjct: 180 VMLYLLDRFSPFGRF-----------------EDALTLSSAMWFSWRVLLNSGLGEGAPR 222 Query: 621 SLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQT---EIAYGTLD 677 S S RI+G VW F +II++SYTANLAAFL + R I D + + Y T+ Sbjct: 223 SFSARILGMVWAGFAMIIVASYTANLAAFLVLRRPEERITGINDPRLRNPSDKFIYATVK 282 Query: 678 SGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEY 737 S +FRR M+ +M+ ++ A+ + VR +K AF+ +S + E+ Sbjct: 283 QSSVDIYFRRQ--VELSTMYRHMEKHN----YESAAEAIQAVRDNK-LHAFIWDSAVLEF 335 Query: 738 IEQRKPCDTMKVGGNLDSKGYGVATPKGSALRTPVNLAVLKLSEQGILDKLKNKWWYDKG 797 E + CD + G G+G+ K S + V+L +LK E G +++L +K W Sbjct: 336 -EASQKCDLVTTGELFFRSGFGIGMRKDSPWKQEVSLNILKSHENGFMEEL-DKTWVRYQ 393 Query: 798 ECGAKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEFCYKSRAESKRMK 852 EC ++ + + L+ N+AGVF ++ GG+ + + IE YKSRAE+KRMK Sbjct: 394 ECDSRSNAP----ATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKSRAEAKRMK 444 >5UN1-B nrPDB Length = 448 Score = 476 bits (1225), Expect = e-134, Method: Composition-based stats. Identities = 138/472 (29%), Positives = 229/472 (48%), Gaps = 70/472 (14%) Query: 418 TIVVTTILESPYVMY---------------------KKNHEQLEGNE----RYEGYCVDL 452 + + T+ E+P+V+ + + EG +G+C+D+ Sbjct: 3 HLSIVTLEEAPFVIVEDVDPLSGTCMRNTVPCRKQIRPENRTEEGGNYIKRCCKGFCIDI 62 Query: 453 AYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEV 512 +IAK V+ Y L +V +GK+G + +WNGM+GE+V RA +AV LTI R EV Sbjct: 63 LKKIAKTVKFTYDLYLVTNGKHGKK--INGVWNGMIGEVVTKRAYMAVGSLTINEERSEV 120 Query: 513 IDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW-MCIVFAYIGVSVVLFLVSRFS 571 +DFS PF+ GIS+M+ + + +FL+P + ++W M V I +V +F+ FS Sbjct: 121 VDFSVPFIETGISVMVSRSNGTVSPS-AFLEPFSADVWVMMFVMLLIVSAVAVFVFEYFS 179 Query: 572 PYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLWFSLGAFMQQGCDI-SPRSLSGRIVGGV 630 P ++ F I ++W G + +P+ + +I+ V Sbjct: 180 PVGYN-----------------GPSFTIGKAIWLLWGLVFNNSLPVQNPKGTTSKIMVSV 222 Query: 631 WWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTE------IAYGTLDSGSTKEF 684 W FF +I ++SYTANLAAF+ R V + D Q +GT+ +GST+ Sbjct: 223 WAFFAVIFLASYTANLAAFMIQRRYVDQVSGLSDKKFQRPNDFSPAFRFGTVPNGSTERN 282 Query: 685 FRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQR-KP 743 R + Y +M SYM F + + KS AF+ ++ + Y+ R + Sbjct: 283 IRNN----YLEMHSYMVK-----FNQRSVQDALLSLKSGKLDAFIYDAAVLNYMAGRDEG 333 Query: 744 CDTMKVGGN--LDSKGYGVATPKGSALRTPVNLAVLKLSEQGILDKLKNKWWYDKGECGA 801 C + +G + GYG+A K S + V+LA+L+L G +++L+ W G C Sbjct: 334 CKLVTIGSGKVFATTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEELEALWL--TGIC-- 389 Query: 802 KDSGSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIEF-CYKSRAESKRMK 852 + ++ +S L + N+AGVFY+L + L+++ ++E YKSRAE+KRMK Sbjct: 390 HNEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIMEHLFYKSRAEAKRMK 441 >3DP4-A nrPDB Length = 278 Score = 229 bits (583), Expect = 5e-60, Method: Composition-based stats. Identities = 142/147 (96%), Positives = 144/147 (97%) Query: 654 RMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTA 713 + +PIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTA Sbjct: 132 KKGTPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTA 191 Query: 714 DGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRTPVN 773 DGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSAL TPVN Sbjct: 192 DGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALGTPVN 251 Query: 774 LAVLKLSEQGILDKLKNKWWYDKGECG 800 LAVLKLSEQGILDKLKNKWWYDKGECG Sbjct: 252 LAVLKLSEQGILDKLKNKWWYDKGECG 278 Score = 212 bits (539), Expect = 5e-55, Method: Composition-based stats. Identities = 135/217 (62%), Positives = 147/217 (67%), Gaps = 8/217 (3%) Query: 403 SDQQISNDSSSSENRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRI 462 S ISNDSS NRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRI Sbjct: 6 SAMGISNDSSRGANRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRI 65 Query: 463 KYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSL 522 KYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSL Sbjct: 66 KYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSL 125 Query: 523 GISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYE--WHLEDN 580 GISIMIKK + LA + + G + F S+ + YE W + Sbjct: 126 GISIMIKKGTP-----IESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKS 180 Query: 581 NEEPRDPQSPPDPPNEFGIFNS-LWFSLGAFMQQGCD 616 E ++ D F L + M + + Sbjct: 181 AEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIE 217 >3FAT-A nrPDB Length = 260 Score = 228 bits (581), Expect = 8e-60, Method: Composition-based stats. Identities = 136/147 (92%), Positives = 144/147 (97%) Query: 654 RMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTA 713 + +PIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMW+YM+SAEPSVFT+TTA Sbjct: 114 KKGTPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTA 173 Query: 714 DGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRTPVN 773 +GVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGS+LRTPVN Sbjct: 174 EGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLRTPVN 233 Query: 774 LAVLKLSEQGILDKLKNKWWYDKGECG 800 LAVLKLSE G+LDKLKNKWWYDKGECG Sbjct: 234 LAVLKLSEAGVLDKLKNKWWYDKGECG 260 Score = 199 bits (505), Expect = 6e-51, Method: Composition-based stats. Identities = 106/169 (62%), Positives = 124/169 (73%), Gaps = 7/169 (4%) Query: 416 NRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYG 475 RT+VVTTI+ESPYVMYKKNHE EGN++YEGYCVDLA EIAKH+ IKYK++IV DGKYG Sbjct: 1 GRTVVVTTIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYG 60 Query: 476 ARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK 535 ARD +TKIWNGMVGELVYG+A+IA+APLTITLVREEVIDFSKPFMSLGISIMIKK Sbjct: 61 ARDADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTP-- 118 Query: 536 PGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYE--WHLEDNNE 582 + LA + + G + F S+ + YE W + E Sbjct: 119 ---IESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAE 164 >1YAE-A nrPDB Length = 312 Score = 228 bits (581), Expect = 8e-60, Method: Composition-based stats. Identities = 85/190 (44%), Positives = 119/190 (62%), Gaps = 20/190 (10%) Query: 405 QQISNDSSSSENRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKY 464 + +N + S NR+++VTTILE PYV++KK+ + L GN+R+EGYC+DL E++ + Y Sbjct: 1 GKPANITDSLSNRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTY 60 Query: 465 KLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGI 524 ++ +V DGKYGA+D WNGMV EL+ +AD+AVAPL IT VRE+VIDFSKPFM+LGI Sbjct: 61 EIRLVEDGKYGAQDDVNGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGI 120 Query: 525 SIMIKKPQKSKPGVFSFL--------------------DPLAYEIWMCIVFAYIGVSVVL 564 SI+ +KP + PGVFSFL D LA + + G ++ Sbjct: 121 SILYRKPNGTNPGVFSFLNGGSLVPRGSERMESPIDSADDLAKQTKIEYGAVEDGATMTF 180 Query: 565 FLVSRFSPYE 574 F S+ S Y+ Sbjct: 181 FKKSKISTYD 190 Score = 221 bits (563), Expect = 1e-57, Method: Composition-based stats. Identities = 78/165 (47%), Positives = 111/165 (67%), Gaps = 7/165 (4%) Query: 653 ERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTT 712 ERM SPI+SA+DLAKQT+I YG ++ G+T FF++SKI+ Y+KMW++M S SV K+ Sbjct: 149 ERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSN 208 Query: 713 ADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRTPV 772 +G+ RV S +AFL+EST E++ QR C+ ++GG +DSKGYGV TP GS R + Sbjct: 209 EEGIQRVLTS--DYAFLMESTTIEFVTQRN-CNLTQIGGLIDSKGYGVGTPMGSPYRDKI 265 Query: 773 NLAVLKLSEQGILDKLKNKWWYDKGECGAKDSGSKDKTSALSLSN 817 +A+L+L E+G L +K KWW G C ++S + SAL + N Sbjct: 266 TIAILQLQEEGKLHMMKEKWWRGNG-CPEEESK---EASALGVQN 306 >5O9A-A nrPDB Length = 264 Score = 227 bits (578), Expect = 2e-59, Method: Composition-based stats. Identities = 127/148 (85%), Positives = 142/148 (95%) Query: 654 RMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTA 713 + +PIESAEDL+KQTEIAYGTLDSGSTKEFFRRSKIAV++KMW+YM+SAEPSVF +TTA Sbjct: 116 KKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTA 175 Query: 714 DGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRTPVN 773 +GVARVRKSKGK+A+LLESTMNEYIEQRKPCDTMKVGGNLDSKGYG+ATPKGS+L VN Sbjct: 176 EGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVN 235 Query: 774 LAVLKLSEQGILDKLKNKWWYDKGECGA 801 LAVLKLSEQG+LDKLKNKWWYDKGECG+ Sbjct: 236 LAVLKLSEQGLLDKLKNKWWYDKGECGS 263 Score = 204 bits (518), Expect = 2e-52, Method: Composition-based stats. Identities = 107/170 (62%), Positives = 123/170 (72%), Gaps = 7/170 (4%) Query: 415 ENRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKY 474 N+T+VVTTILESPYVM KKNHE LEGNERYEGYCVDLA EIAKH KYKL+IVGDGKY Sbjct: 2 ANKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKY 61 Query: 475 GARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKS 534 GARD +TKIWNGMVGELVYG+ADIA+APLTIT VREEVIDFSKPFMSLGISIMIKK Sbjct: 62 GARDADTKIWNGMVGELVYGKADIAIAPLTITYVREEVIDFSKPFMSLGISIMIKKGTP- 120 Query: 535 KPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYE--WHLEDNNE 582 + L+ + + G + F S+ + ++ W + E Sbjct: 121 ----IESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAE 166 >2XXT-A nrPDB Length = 261 Score = 212 bits (540), Expect = 5e-55, Method: Composition-based stats. Identities = 70/151 (46%), Positives = 101/151 (66%), Gaps = 4/151 (2%) Query: 651 TVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTK 710 + R +PI+SA+DLAKQT+I YG ++ G+T FF++SKI+ Y+KMW++M S SV K Sbjct: 113 ILYRKGTPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVK 172 Query: 711 TTADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRT 770 + +G+ RV S +AFL+EST E++ QR C+ ++GG +DSKGYGV TP GS R Sbjct: 173 SNEEGIQRVLTS--DYAFLMESTTIEFVTQRN-CNLTQIGGLIDSKGYGVGTPMGSPYRD 229 Query: 771 PVNLAVLKLSEQGILDKLKNKWWYDKGECGA 801 + +A+L+L E+G L +K KWW G C Sbjct: 230 KITIAILQLQEEGKLHMMKEKWWRGNG-CPE 259 Score = 212 bits (539), Expect = 6e-55, Method: Composition-based stats. Identities = 75/160 (46%), Positives = 105/160 (65%), Gaps = 5/160 (3%) Query: 415 ENRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKY 474 NR+++VTTILE PYV++KK+ + L GN+R+EGYC+DL E++ + Y++ +V DGKY Sbjct: 2 SNRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDGKY 61 Query: 475 GARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKS 534 GA+D WNGMV EL+ +AD+AVAPL IT VRE+VIDFSKPFM+LGISI+ +K Sbjct: 62 GAQDDVNGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRKGTP- 120 Query: 535 KPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYE 574 D LA + + G ++ F S+ S Y+ Sbjct: 121 ----IDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYD 156 >4MF3-A nrPDB Length = 261 Score = 210 bits (535), Expect = 2e-54, Method: Composition-based stats. Identities = 81/173 (46%), Positives = 111/173 (64%), Gaps = 8/173 (4%) Query: 413 SSENRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDG 472 S NRT++VTTILE PYVMY+K+ + L GN+R+EGYC+DL E++ + Y + +V DG Sbjct: 1 SLANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLVPDG 60 Query: 473 KYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQ 532 KYGA++ + WNGMV EL+ RAD+AVAPLTIT VRE+VIDFSKPFM+LGISI+ +K Sbjct: 61 KYGAQNDK-GEWNGMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKGT 119 Query: 533 KSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYE--WHLEDNNEE 583 D LA + + G ++ F S+ S YE W + ++ Sbjct: 120 P-----IDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQ 167 Score = 209 bits (532), Expect = 4e-54, Method: Composition-based stats. Identities = 68/152 (44%), Positives = 100/152 (65%), Gaps = 4/152 (2%) Query: 651 TVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTK 710 + R +PI+SA+DLAKQT+I YG + GST FF++SKI+ YEKMW++M S + + + Sbjct: 113 ILYRKGTPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQTALVR 172 Query: 711 TTADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRT 770 + +G+ RV + +A L+EST EY+ QR C+ ++GG +DSKGYGV TP GS R Sbjct: 173 NSDEGIQRVLTT--DYALLMESTSIEYVTQRN-CNLTQIGGLIDSKGYGVGTPIGSPYRD 229 Query: 771 PVNLAVLKLSEQGILDKLKNKWWYDKGECGAK 802 + +A+L+L E+G L +K KWW G C + Sbjct: 230 KITIAILQLQEEGKLHMMKEKWWRGNG-CPEE 260 >4IGR-A nrPDB Length = 258 Score = 208 bits (528), Expect = 1e-53, Method: Composition-based stats. Identities = 81/202 (40%), Positives = 117/202 (57%), Gaps = 10/202 (4%) Query: 412 SSSENRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGD 471 NR+++VTT+LE P+VM++K+ L GN+R+EGYC+DL E+A + Y++ +V D Sbjct: 1 GPGTNRSLIVTTLLEEPFVMFRKSDRTLYGNDRFEGYCIDLLKELAHILGFSYEIRLVED 60 Query: 472 GKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKP 531 GKYGA+D + WNGMV EL+ +AD+AVAPLTIT VRE+ IDFSKPFM+LG+SI+ +K Sbjct: 61 GKYGAQDDK-GQWNGMVKELIDHKADLAVAPLTITHVREKAIDFSKPFMTLGVSILYRKG 119 Query: 532 QKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPP 591 D LA + + G ++ F S+ S +E + +P S Sbjct: 120 TP-----IDSADDLAKQTKIEYGAVKDGATMTFFKKSKISTFEKMWAFMSSKP----SAL 170 Query: 592 DPPNEFGIFNSLWFSLGAFMQQ 613 NE GI +L M+ Sbjct: 171 VKNNEEGIQRTLTADYALLMES 192 Score = 201 bits (510), Expect = 1e-51, Method: Composition-based stats. Identities = 67/150 (44%), Positives = 98/150 (65%), Gaps = 5/150 (3%) Query: 651 TVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTK 710 + R +PI+SA+DLAKQT+I YG + G+T FF++SKI+ +EKMW++M S++PS K Sbjct: 114 ILYRKGTPIDSADDLAKQTKIEYGAVKDGATMTFFKKSKISTFEKMWAFM-SSKPSALVK 172 Query: 711 TTADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRT 770 +G+ R + +A L+EST EYI QR C+ ++GG +DSKGYG+ TP GS R Sbjct: 173 NNEEGIQRTLTA--DYALLMESTTIEYITQRN-CNLTQIGGLIDSKGYGIGTPMGSPYRD 229 Query: 771 PVNLAVLKLSEQGILDKLKNKWWYDKGECG 800 + +A+L+L E+ L +K KWW G C Sbjct: 230 KITIAILQLQEEDKLHIMKEKWWRGSG-CP 258 >5EHM-A nrPDB Length = 268 Score = 203 bits (517), Expect = 2e-52, Method: Composition-based stats. Identities = 84/152 (55%), Positives = 106/152 (69%), Gaps = 4/152 (2%) Query: 651 TVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTK 710 + R +PIESAEDLAKQT I YG L GST FFR SKI+ Y++MWS+M+SA PSVFT Sbjct: 117 ILYRKGTPIESAEDLAKQTRIKYGALKGGSTAAFFRDSKISTYQRMWSFMESARPSVFTA 176 Query: 711 TTADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRT 770 + +GV RV K KG +AFL+EST EY+ +R C+ +VGG LD+K YG+ATP S RT Sbjct: 177 SNGEGVERVAKGKGSYAFLMESTSIEYVTERN-CELTQVGGMLDTKSYGIATPPNSPYRT 235 Query: 771 PVNLAVLKLSEQGILDKLKNKWWYDK---GEC 799 +N +LKL E+G L LK KWW +K G+C Sbjct: 236 AINSVILKLQEEGKLHILKTKWWKEKRGGGKC 267 Score = 188 bits (476), Expect = 1e-47, Method: Composition-based stats. Identities = 67/165 (40%), Positives = 102/165 (61%), Gaps = 5/165 (3%) Query: 411 SSSSENRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVG 470 S++ +N+T+VVTTIL +PY M K++ L GN+++EGY VDL +EI+K + YK+ +V Sbjct: 2 SANLKNKTLVVTTILSNPYCMRKESAIPLSGNDQFEGYAVDLIHEISKSLGFNYKIQLVP 61 Query: 471 DGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKK 530 DG YG+ + T WNGM+ EL+ RAD+A+A LTIT RE+ +DF+ PFM+LG+SI+ +K Sbjct: 62 DGSYGSLNKLTGEWNGMIRELLEQRADLAIADLTITFEREQAVDFTTPFMNLGVSILYRK 121 Query: 531 PQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEW 575 + LA + + G + F S+ S Y+ Sbjct: 122 GTP-----IESAEDLAKQTRIKYGALKGGSTAAFFRDSKISTYQR 161 >5IKB-A nrPDB Length = 257 Score = 200 bits (509), Expect = 2e-51, Method: Composition-based stats. Identities = 78/160 (48%), Positives = 106/160 (66%), Gaps = 6/160 (3%) Query: 416 NRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYG 475 N T+VVTTILE+PY+M K NH+ +EGN+RYEG+CVD+ E+A+ +R YK+ +VGDG YG Sbjct: 3 NTTLVVTTILENPYLMLKGNHQDMEGNDRYEGFCVDMLKELAEILRFNYKIRLVGDGVYG 62 Query: 476 ARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK 535 + W GMVGEL+ +AD+AVA LTIT RE+VIDFSKPFM+LGISI+ +K Sbjct: 63 VPEA-NGTWTGMVGELIARKADLAVAGLTITAEREKVIDFSKPFMTLGISILYRKGTP-- 119 Query: 536 PGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEW 575 +D LA + + + G S+ F SR+ Y+ Sbjct: 120 ---IESVDDLADQTAIEYGTIHGGSSMTFFQNSRYQTYQR 156 Score = 199 bits (506), Expect = 4e-51, Method: Composition-based stats. Identities = 75/150 (50%), Positives = 101/150 (67%), Gaps = 4/150 (2%) Query: 651 TVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTK 710 + R +PIES +DLA QT I YGT+ GS+ FF+ S+ Y++MW+YM S +PSVF K Sbjct: 112 ILYRKGTPIESVDDLADQTAIEYGTIHGGSSMTFFQNSRYQTYQRMWNYMYSKQPSVFVK 171 Query: 711 TTADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRT 770 +T +G+ARV S +AFLLESTMNEY QR C+ ++GG LD+KGYG+ P GS R Sbjct: 172 STEEGIARVLNS--NYAFLLESTMNEYYRQRN-CNLTQIGGLLDTKGYGIGMPVGSVFRD 228 Query: 771 PVNLAVLKLSEQGILDKLKNKWWYDKGECG 800 +LA+L+L E L+ LK KWW + G+C Sbjct: 229 EFDLAILQLQENNRLEILKRKWW-EGGKCP 257 >5DT6-A nrPDB Length = 267 Score = 193 bits (490), Expect = 3e-49, Method: Composition-based stats. Identities = 81/146 (55%), Positives = 105/146 (71%), Gaps = 1/146 (0%) Query: 654 RMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTA 713 + +PI++ EDL QT++ YGTL GST EFFRRS+I ++ KMW YM +A T Sbjct: 122 KKGTPIKTPEDLTMQTDVNYGTLLYGSTWEFFRRSQIGLHNKMWEYM-NANQHHSVHTYD 180 Query: 714 DGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRTPVN 773 +G+ RVR+SKGK+A L+ES NEY+ R PCDTMKVG N+D+KG+GVATP GS LR +N Sbjct: 181 EGIRRVRQSKGKYALLVESPKNEYVNARPPCDTMKVGRNIDTKGFGVATPIGSPLRKRLN 240 Query: 774 LAVLKLSEQGILDKLKNKWWYDKGEC 799 AVL L E G L +++NKWW+DK EC Sbjct: 241 EAVLTLKENGELLRIRNKWWFDKTEC 266 Score = 168 bits (424), Expect = 1e-41, Method: Composition-based stats. Identities = 72/178 (40%), Positives = 100/178 (56%), Gaps = 10/178 (5%) Query: 411 SSSSENRTIVVTTILESPYVMYKKNH--EQLEGNERYEGYCVDLAYEIAKHVRIKYKLSI 468 S N T +V+++LE PY+ K+ E L GN+R+EGYC DLA +A + IKY++ + Sbjct: 1 GSYDRNHTYIVSSLLEEPYLSLKQYTYGESLVGNDRFEGYCKDLADMLAAQLGIKYEIRL 60 Query: 469 VGDGKYGARDP-ETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIM 527 V DG YGA + W+GMVGEL+ ADIA++ +TIT RE VIDFSKPFM+LGISIM Sbjct: 61 VQDGNYGAENQYAPGGWDGMVGELIRKEADIAISAMTITAERERVIDFSKPFMTLGISIM 120 Query: 528 IKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYE--WHLEDNNEE 583 IKK K + L + + G + F S+ + W + N+ Sbjct: 121 IKKGTPIKTP-----EDLTMQTDVNYGTLLYGSTWEFFRRSQIGLHNKMWEYMNANQH 173 >4WXJ-A nrPDB Length = 269 Score = 170 bits (431), Expect = 2e-42, Method: Composition-based stats. Identities = 52/146 (35%), Positives = 83/146 (56%), Gaps = 1/146 (0%) Query: 651 TVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTK 710 + + I S DL Q ++ +GT+ G+T +F S W+ M S +P FTK Sbjct: 120 ILSYKGTDIGSLHDLVDQNKVQFGTIRGGATSVYFSESNDTDNRMAWNKMLSFKPDAFTK 179 Query: 711 TTADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRT 770 +GV RV+ SKG +AFL+E+T +Y QR C+ ++G + K YG+A P + R+ Sbjct: 180 NNEEGVDRVKLSKGTYAFLMETTNLQYYVQRN-CELTQIGESFGEKHYGIAVPLNADFRS 238 Query: 771 PVNLAVLKLSEQGILDKLKNKWWYDK 796 +++ +L+LSE+G L KL+NKW+ Sbjct: 239 NLSVGILRLSERGELFKLRNKWFNSN 264 Score = 146 bits (367), Expect = 5e-35, Method: Composition-based stats. Identities = 52/150 (34%), Positives = 74/150 (49%), Gaps = 7/150 (4%) Query: 418 TIVVTTILESPYVMYKKNHE--QLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYG 475 V T + PY +++ E EGNER+EGY VDL Y +A+ + + V D KYG Sbjct: 10 RYTVATRVGKPYFSWREEPEGVHYEGNERFEGYAVDLIYMLAQECKFDFNFEPVRDNKYG 69 Query: 476 ARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSK 535 + D T W+G++ +L+ A I + LTIT R V+DF+ PFM LGISI+ K Sbjct: 70 SYDANTDEWDGIIRQLIDNNAQIGICDLTITQARRSVVDFTVPFMQLGISILSYKGTD-- 127 Query: 536 PGVFSFLDPLAYEIWMCIVFAYIGVSVVLF 565 L L + + G + V F Sbjct: 128 ---IGSLHDLVDQNKVQFGTIRGGATSVYF 154 >5CC2-A nrPDB Length = 265 Score = 170 bits (430), Expect = 3e-42, Method: Composition-based stats. Identities = 47/158 (29%), Positives = 81/158 (51%), Gaps = 10/158 (6%) Query: 651 TVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRS------KIAVYEKMWSYMKSAE 704 + R + I+S +DL+KQT+I YGT+ + + R + ++Y +MW + + Sbjct: 109 VLLRRGTSIQSLQDLSKQTDIPYGTVLDSAVYQHVRMKGLNPFERDSMYSQMWRMINRSN 168 Query: 705 PSVFTKTTADGVARVRKSK-GKFAFLLESTMNEYIEQRKP-CDTMKVGGNLDSKGYGVAT 762 S + A ++K K G +AF+ ++ + EY+ P C VG + +GYG+A Sbjct: 169 GS--ENNVLESQAGIQKVKYGNYAFVWDAAVLEYVAINDPDCSFYTVGNTVADRGYGIAL 226 Query: 763 PKGSALRTPVNLAVLKLSEQGILDKLKNKWWYDKGECG 800 GS R + +L+L + G +D LK+KWW G+C Sbjct: 227 QHGSPYRDVFSQRILELQQSGDMDILKHKWWPKNGQCD 264 Score = 145 bits (365), Expect = 8e-35, Method: Composition-based stats. Identities = 44/157 (28%), Positives = 81/157 (51%), Gaps = 8/157 (5%) Query: 419 IVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARD 478 + V T+LE P+VM +N L ++Y+G+ +D+ ++ ++ Y++ + D KYG+ Sbjct: 5 LRVVTVLEEPFVMVSEN--VLGKPKKYQGFSIDVLDALSNYLGFNYEIYVAPDHKYGSPQ 62 Query: 479 PETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGV 538 E WNG+VGELV+ RADI ++ LTIT RE V+DF+ +M + +++++ Sbjct: 63 -EDGTWNGLVGELVFKRADIGISALTITPDRENVVDFTTRYMDYSVGVLLRRG-----TS 116 Query: 539 FSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEW 575 L L+ + + + +P+E Sbjct: 117 IQSLQDLSKQTDIPYGTVLDSAVYQHVRMKGLNPFER 153 >5I2K-B nrPDB Length = 293 Score = 161 bits (406), Expect = 2e-39, Method: Composition-based stats. Identities = 37/154 (24%), Positives = 68/154 (44%), Gaps = 12/154 (7%) Query: 651 TVERMVSPIESAEDLAKQT---EIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSV 707 + + + I D + + Y T+ S +FRR M+ +M+ Sbjct: 149 ILVKKGTRITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQ--VELSTMYRHMEKHN--- 203 Query: 708 FTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSA 767 ++ A+ + VR +K AF+ +S + E+ E + CD + G G+G+ K S Sbjct: 204 -YESAAEAIQAVRDNK-LHAFIWDSAVLEF-EASQKCDLVTTGELFFRSGFGIGMRKDSP 260 Query: 768 LRTPVNLAVLKLSEQGILDKLKNKWWYDKGECGA 801 + V+L++LK E G ++ L +K W EC + Sbjct: 261 WKQNVSLSILKSHENGFMEDL-DKTWVRYQECDS 293 Score = 138 bits (348), Expect = 1e-32, Method: Composition-based stats. Identities = 55/228 (24%), Positives = 91/228 (39%), Gaps = 40/228 (17%) Query: 413 SSENRTIVVTTILESPYVMYKKNHEQLEGNERYE-------------------------- 446 S + + + TI + P+V K E + Sbjct: 1 GSMSTRLKIVTIHQEPFVYVKPTLSDGTCKEEFTVNGDPVKKVICTGPNDTSPGSPRHTV 60 Query: 447 -----GYCVDLAYEIAKHVRIKYKLSIVGDGKYGAR----DPETKIWNGMVGELVYGRAD 497 G+C+DL ++A+ + Y++ +V DGK+G + + K WNGM+GEL+ G+AD Sbjct: 61 PQCCYGFCIDLLIKLARTMNFTYEVHLVADGKFGTQERVNNSNKKEWNGMMGELLSGQAD 120 Query: 498 IAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAY 557 + VAPLTI R + I+FSKPF G++I++KK ++ + Sbjct: 121 MIVAPLTINNERAQYIEFSKPFKYQGLTILVKK--GTRITGINDPRLRNPSDKFIYATVK 178 Query: 558 IGVSVVLFLVS-RFSPYEWHLEDNNEEPRDPQSPPDPPNEFGIFNSLW 604 + F S H+E +N E N+ F +W Sbjct: 179 QSSVDIYFRRQVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAF--IW 224 >4YKP-A nrPDB Length = 256 Score = 159 bits (402), Expect = 4e-39, Method: Composition-based stats. Identities = 42/161 (26%), Positives = 76/161 (47%), Gaps = 3/161 (1%) Query: 411 SSSSENRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVG 470 S + R + + ++ E P++ + E EGN+ + G D+ ++++ + Y+ Sbjct: 2 SKNLIGRHLRLGSVEEQPFMFF--ATEGCEGNDCWSGMVNDMVVKLSEDLGFTYEYIQPD 59 Query: 471 DGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKK 530 D K+GA + T WNGM+ +L+ + D+ L+ R+ ID+S PFM GI ++K Sbjct: 60 DRKFGALNKTTNEWNGMIRDLLDDKTDMIAIDLSTNSARKSAIDYSFPFMDAGIKAVVKG 119 Query: 531 PQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFS 571 + V LD Y+ W I + + SR+S Sbjct: 120 EGTTLNQVLELLDQDKYK-WGVIGSRHPETLLKTHRDSRYS 159 Score = 73.3 bits (178), Expect = 5e-13, Method: Composition-based stats. Identities = 31/149 (20%), Positives = 57/149 (38%), Gaps = 9/149 (6%) Query: 651 TVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTK 710 V+ + + +L Q + +G + S + + + + Y ++ + V K Sbjct: 116 VVKGEGTTLNQVLELLDQDKYKWGVIGSRHPETLLKTHRDSRYSRL------VDEGVELK 169 Query: 711 TTADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRT 770 + +R G F F+ E + + CD VG S Y PK S ++ Sbjct: 170 DLNHAIETLR--GGLFVFIDEGPVLAHNLIS-DCDVFSVGEEFQSFEYAFGLPKDSPYKS 226 Query: 771 PVNLAVLKLSEQGILDKLKNKWWYDKGEC 799 ++ +LK E+G +D L KW C Sbjct: 227 LIDSHLLKFREEGFIDILWEKWSSGNSVC 255 >5H8N-A nrPDB Length = 285 Score = 152 bits (383), Expect = 7e-37, Method: Composition-based stats. Identities = 36/155 (23%), Positives = 64/155 (41%), Gaps = 20/155 (12%) Query: 655 MVSPIESAEDLAKQ------TEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVF 708 + + D Q +GT+ +GST+ R + Y M YM Sbjct: 141 RGTQVTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNIRNN----YPYMHQYMTKFNQ--- 193 Query: 709 TKTTADGVARVRKSKGKFAFLLESTMNEYIEQR-KPCDTMKVGGN--LDSKGYGVATPKG 765 K D + ++ K AF+ ++ + Y R + C + +G + GYG+A KG Sbjct: 194 -KGVEDALVSLKTGK-LDAFIYDAAVLNYKAGRDEGCKLVTIGSGYIFATTGYGIALQKG 251 Query: 766 SALRTPVNLAVLKLSEQGILDKLKNKWWYDKGECG 800 S + ++LA+L+ G +++L+ W G C Sbjct: 252 SPWKRQIDLALLQFVGDGEMEELETLWL--TGICH 284 Score = 136 bits (341), Expect = 5e-32, Method: Composition-based stats. Identities = 51/175 (29%), Positives = 84/175 (48%), Gaps = 27/175 (15%) Query: 412 SSSENRTIVVTTILESPYV---------------------MYKKNHEQLEG---NERYEG 447 S ++ + + T+ E+P+V K N+ EG + +G Sbjct: 1 GSPDDNHLSIVTLEEAPFVIVEDIDPLTETCVRNTVPCRKFVKINNSTNEGMNVKKCCKG 60 Query: 448 YCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITL 507 +C+D+ ++++ V+ Y L +V +GK+G + +WNGM+GE+VY RA +AV LTI Sbjct: 61 FCIDILKKLSRTVKFTYDLYLVTNGKHGKK--VNNVWNGMIGEVVYQRAVMAVGSLTINE 118 Query: 508 VREEVIDFSKPFMSLGISIMIKKP-QKSKPGVFSFLDPLAYEIWMCIVFAYIGVS 561 R EV+DFS PF+ GIS+M+ + Q + F P Y G + Sbjct: 119 ERSEVVDFSVPFVETGISVMVSRGTQVTGLSDKKFQRPHDYSPPFRFGTVPNGST 173 >2RC9-A nrPDB Length = 294 Score = 146 bits (368), Expect = 4e-35, Method: Composition-based stats. Identities = 35/156 (22%), Positives = 65/156 (41%), Gaps = 14/156 (8%) Query: 650 LTVERMVSPIESAEDLAKQTE---IAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPS 706 + V + + D +GT+ S +++ R+S + +M YM+ Sbjct: 147 ILVRTRGTELSGIHDPKLHHPSQGFRFGTVRESSAEDYVRQS----FPEMHEYMRRYN-- 200 Query: 707 VFTKTTADGVARVRKSKGKF-AFLLESTMNEY-IEQRKPCDTMKVGGNLDSKGYGVATPK 764 T DGV ++ K AF+++ + +Y + C + VG +GYG+ P Sbjct: 201 --VPATPDGVQYLKNDPEKLDAFIMDKALLDYEVSIDADCKLLTVGKPFAIEGYGIGLPP 258 Query: 765 GSALRTPVNLAVLKLSEQGILDKLKNKWWYDKGECG 800 S L + ++ + + G +D L +KW Y CG Sbjct: 259 NSPLTSNISELISQYKSHGFMDVLHDKW-YKVVPCG 293 Score = 117 bits (293), Expect = 2e-26, Method: Composition-based stats. Identities = 41/158 (25%), Positives = 71/158 (44%), Gaps = 37/158 (23%) Query: 418 TIVVTTILESPYVMYKKNHE-----------------------------------QLEGN 442 + V T++E P+V ++ + ++ Sbjct: 6 HLRVVTLIEHPFVFTREVDDEGLCPAGQLCLDPMTNDSSMLDRLFSSLHSSNDTVPIKFK 65 Query: 443 ERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAP 502 + GYC+DL ++A+ + + L IVGDGKYGA + W G+VG+L+ G A++AV Sbjct: 66 KCCYGYCIDLLEQLAEDMNFDFDLYIVGDGKYGAW--KNGHWTGLVGDLLSGTANMAVTS 123 Query: 503 LTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFS 540 +I R +VIDF+ PF S + I+++ G+ Sbjct: 124 FSINTARSQVIDFTSPFFSTSLGILVRTRGTELSGIHD 161 >2RCB-A nrPDB Length = 292 Score = 141 bits (356), Expect = 9e-34, Method: Composition-based stats. Identities = 34/156 (21%), Positives = 66/156 (42%), Gaps = 14/156 (8%) Query: 650 LTVERMVSPIESAEDLAKQTE---IAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPS 706 + V + + D +GT+ S + + + S + +M ++M+ Sbjct: 145 IMVRTRGTELSGIHDPKLHHPSQGFRFGTVWESSAEAYIKAS----FPEMHAHMRRHS-- 198 Query: 707 VFTKTTADGVARVRKSKGKF-AFLLESTMNEY-IEQRKPCDTMKVGGNLDSKGYGVATPK 764 TT GVA + K AF+++ ++ +Y + C + VG +GYG+ P+ Sbjct: 199 --APTTPHGVAMLTSDPPKLNAFIMDKSLLDYEVSIDADCKLLTVGKPFAIEGYGIGLPQ 256 Query: 765 GSALRTPVNLAVLKLSEQGILDKLKNKWWYDKGECG 800 S L + ++ + + G +D L +KW Y CG Sbjct: 257 NSPLTSNLSEFISRYKSSGFIDLLHDKW-YKMVPCG 291 Score = 121 bits (303), Expect = 2e-27, Method: Composition-based stats. Identities = 65/288 (22%), Positives = 104/288 (36%), Gaps = 52/288 (18%) Query: 419 IVVTTILESPYVMYKKNHEQLEGN---------------------------------ERY 445 + V T++E P+V +++ E + Sbjct: 7 LRVVTLVEHPFVFTRESDEDGQCPAGQLCLDPGTNDSARLDALFAALVNGSVPRTLRRCC 66 Query: 446 EGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTI 505 GYC+DL +A+ + ++L IVGDGKYGA W G+VG+L+ GRA +AV +I Sbjct: 67 YGYCIDLLERLAEDLAFDFELYIVGDGKYGAL--RDGRWTGLVGDLLAGRAHMAVTSFSI 124 Query: 506 TLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDP--LAYEIWMCIVFAYIGVSVV 563 R +V+DF+ PF S + IM++ G+ DP + + Sbjct: 125 NSARSQVVDFTSPFFSTSLGIMVRTRGTELSGIH---DPKLHHPSQGFRFGTVWESSAEA 181 Query: 564 LFLVSRFSPYEWHLEDNNEEPRDPQS------PPDPPNEFGIFNSLWFSLGAFMQQGCDI 617 S P + P P P N F + SL + C + Sbjct: 182 YIKASF--PEMHAHMRRHSAPTTPHGVAMLTSDPPKLNAFIMDKSL-LDYEVSIDADCKL 238 Query: 618 SPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDL 665 I G + L S T+NL+ F++ + I+ D Sbjct: 239 LTVGKPFAIEG---YGIGLPQNSPLTSNLSEFISRYKSSGFIDLLHDK 283 >3OEK-A nrPDB Length = 286 Score = 137 bits (346), Expect = 2e-32, Method: Composition-based stats. Identities = 34/155 (21%), Positives = 67/155 (43%), Gaps = 20/155 (12%) Query: 655 MVSPIESAEDLAKQ------TEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVF 708 + + D Q + +GT+ +GST++ R + Y M SYM Sbjct: 142 RGTTVSGLSDRKFQRPQEQYPPLKFGTVPNGSTEKNIRSN----YPDMHSYMVRYNQ--- 194 Query: 709 TKTTADGVARVRKSKGKFAFLLESTMNEYIEQ-RKPCDTMKVGGN--LDSKGYGVATPKG 765 + + +++ K AF+ ++ + Y+ + + C + +G + GYG+A KG Sbjct: 195 -PRVEEALTQLKAGK-LDAFIYDAAVLNYMARKDEGCKLVTIGSGKVFATTGYGIALHKG 252 Query: 766 SALRTPVNLAVLKLSEQGILDKLKNKWWYDKGECG 800 S + P++LA+L+ ++ L+ W G C Sbjct: 253 SRWKRPIDLALLQFLGDDEIEMLERLWL--SGICH 285 Score = 134 bits (337), Expect = 2e-31, Method: Composition-based stats. Identities = 40/147 (27%), Positives = 68/147 (46%), Gaps = 28/147 (19%) Query: 413 SSENRTIVVTTILESPYVMYKKNH--------------------------EQLEGNERYE 446 + + + V T+ E P+V+ + + Sbjct: 1 GDDTQHLTVATLEERPFVIVEPADPISGTCIRDSVPCRSQLNRTHSPPPDAPRPEKRCCK 60 Query: 447 GYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTIT 506 G+C+D+ +A + Y L +V +GK+G + +WNGM+GE+ Y RAD+A+ LTI Sbjct: 61 GFCIDILKRLAHTIGFSYDLYLVTNGKHGKK--IDGVWNGMIGEVFYQRADMAIGSLTIN 118 Query: 507 LVREEVIDFSKPFMSLGISIMIKKPQK 533 R E++DFS PF+ GIS+M+ + Sbjct: 119 EERSEIVDFSVPFVETGISVMVARGTT 145 >4ZDM-A nrPDB Length = 261 Score = 126 bits (317), Expect = 3e-29, Method: Composition-based stats. Identities = 31/144 (21%), Positives = 61/144 (42%), Gaps = 2/144 (1%) Query: 411 SSSSENRTIVVTTILESPYVMYKK-NHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIV 469 S++ + + I E P++ + Y G V++ +++ + Y Sbjct: 2 SNNLNGMHLRLGIIPEMPFISEPSLGCTNIRDPSCYTGVNVEIVSMMSQDLNFTYNFITP 61 Query: 470 GDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIK 529 D K+G ++ T WNG++ +L+ + D+ V L+ VR+ IDFS M G+ ++K Sbjct: 62 EDLKFGGKNSTTGEWNGLIRDLLDNKTDMIVVALSNNAVRKADIDFSLSMMDGGLGALVK 121 Query: 530 KPQKSKPGVFSFLDPLAYEIWMCI 553 L+ Y+ W + Sbjct: 122 SDGTDLSHPLELLNQDKYQ-WGVV 144 Score = 62.5 bits (150), Expect = 9e-10, Method: Composition-based stats. Identities = 31/142 (21%), Positives = 63/142 (44%), Gaps = 9/142 (6%) Query: 651 TVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTK 710 V+ + + +L Q + +G +DS + + ++ A Y ++ AE +V Sbjct: 119 LVKSDGTDLSHPLELLNQDKYQWGVVDSRNPELLLASNQNADYNRI------AEDAVKVG 172 Query: 711 TTADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRT 770 + +G+ R+R G F F+ E Y + + CD +++G K S + Sbjct: 173 SYGEGLERMR--AGGFVFIDEIPGINYATKGE-CDIVQIGETFQPFELAFGLRKNSPFKN 229 Query: 771 PVNLAVLKLSEQGILDKLKNKW 792 V+ +L + EQG++ +L K+ Sbjct: 230 LVDTFMLGIREQGVISELYAKY 251 >5TUJ-C nrPDB Length = 235 Score = 126 bits (317), Expect = 4e-29, Method: Composition-based stats. Identities = 38/165 (23%), Positives = 74/165 (44%), Gaps = 19/165 (11%) Query: 418 TIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGAR 477 T+ V T + +K + N +Y G+ +DLA +AK + +K + Sbjct: 13 TLRVGTDADYKPFSFK------DKNGQYTGFDIDLAKALAKELGVKVEFVPT-------- 58 Query: 478 DPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPG 537 W+G++ L G+ DI ++ +TIT R++ +DFS P+M+ G +I++KK K Sbjct: 59 -----TWDGIIPALQTGKFDIVMSGMTITPERKKKVDFSDPYMTAGQTILVKKDNADKIK 113 Query: 538 VFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNE 582 F L+ ++ + + + ++ +E + E E Sbjct: 114 SFEDLNKPDVKVAVQLGTTSEQAAKEFLPKAKIRTFENNAEAFQE 158 Score = 50.2 bits (118), Expect = 4e-06, Method: Composition-based stats. Identities = 35/150 (23%), Positives = 57/150 (38%), Gaps = 22/150 (14%) Query: 650 LTVERMVSPIESAEDLAK---QTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPS 706 L + I+S EDL K + + GT + KEF ++KI +E Sbjct: 103 LVKKDNADKIKSFEDLNKPDVKVAVQLGTTSEQAAKEFLPKAKIRTFE------------ 150 Query: 707 VFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRKP-CDTMKVGGNLDSKGYGVATPKG 765 A+ V + A + +S + Y ++ P + V + G A KG Sbjct: 151 ----NNAEAFQEVVSGRAD-AMVTDSPVAAYYAKKNPGLAVVVVDEPFTHEPLGFAIRKG 205 Query: 766 SA-LRTPVNLAVLKLSEQGILDKLKNKWWY 794 L VN + ++ + G DKL KW+ Sbjct: 206 DPELLNWVNNWLKQMKKDGTYDKLYEKWFK 235 >4ZV2-A nrPDB Length = 233 Score = 104 bits (258), Expect = 2e-22, Method: Composition-based stats. Identities = 32/124 (25%), Positives = 57/124 (45%), Gaps = 19/124 (15%) Query: 418 TIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGAR 477 T+ V T P +K N + G+ +DLA IAK + +K + + Sbjct: 11 TLRVGTEATFPPFGFKDE------NGKLVGFDIDLAKAIAKKLGVKVEFKPMD------- 57 Query: 478 DPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPG 537 ++G++ L G+ D+ +A +TIT R++ +DFS P+ G +I++KK S Sbjct: 58 ------FDGIIPALQSGKIDVVIAGMTITEERKKQVDFSDPYFEAGQAIVVKKGNDSIKS 111 Query: 538 VFSF 541 + Sbjct: 112 LEDL 115 Score = 52.5 bits (124), Expect = 9e-07, Method: Composition-based stats. Identities = 30/146 (20%), Positives = 61/146 (41%), Gaps = 16/146 (10%) Query: 650 LTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFT 709 + V++ I+S EDL + G ++++ ++ K+ + F+ Sbjct: 100 IVVKKGNDSIKSLEDLKGK---KVGVQLGSTSEQHVKKVAKDAGVKVKKF------DNFS 150 Query: 710 KTTADGVARVRKSKGKFAFLLESTM-NEYIEQRKPCDTMKVGGNLDSKGYGVATPKG-SA 767 + + KS A + ++ + Y++Q VG + YG+A KG S Sbjct: 151 EAFQE-----LKSGRVDAVVTDNAVALAYVKQNPNAGVKIVGETFSGEPYGIAVRKGNSE 205 Query: 768 LRTPVNLAVLKLSEQGILDKLKNKWW 793 L +N A+ ++ + G DK+ KW+ Sbjct: 206 LLEKINKALEEMKKDGTYDKIYEKWF 231 >4PSH-A nrPDB Length = 227 Score = 103 bits (256), Expect = 4e-22, Method: Composition-based stats. Identities = 27/106 (25%), Positives = 54/106 (50%), Gaps = 13/106 (12%) Query: 437 EQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRA 496 E ++ N G+ VDLA EIA+ + ++ K+ ++G++ L+ + Sbjct: 23 EFVDENGNIVGFDVDLAKEIARRLGVELKIV-------------DMTFDGLIPSLLTKKI 69 Query: 497 DIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFL 542 D+ ++ +TIT R++V+ FS P+ G I+++K +P + L Sbjct: 70 DVIISGMTITEERKKVVAFSDPYFDAGQVIVVRKDSDFRPKTYEDL 115 Score = 35.5 bits (80), Expect = 0.11, Method: Composition-based stats. Identities = 25/93 (26%), Positives = 37/93 (39%), Gaps = 12/93 (12%) Query: 714 DGVARVRKSKGKFAFL-----------LESTMNEYIEQRKPCDTMKVGGNLDSKGYGVAT 762 DG+ VR K AFL L+S + P D + G L S+ YG+A Sbjct: 136 DGIKVVRFDKFTDAFLELKRGRADAVVLDSATARAFVAKNP-DLVISSGVLSSEQYGIAV 194 Query: 763 PKGSALRTPVNLAVLKLSEQGILDKLKNKWWYD 795 K +VL+ ++ D L KW+ + Sbjct: 195 RKEDTDLLEFINSVLRELKKSPYDVLIEKWFSE 227 >5JOS-A nrPDB Length = 247 Score = 99.5 bits (246), Expect = 5e-21, Method: Composition-based stats. Identities = 27/126 (21%), Positives = 55/126 (43%), Gaps = 19/126 (15%) Query: 418 TIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGAR 477 T+ V T + Y+ +Y G+ +D+A +AK + +K + Sbjct: 24 TLRVGTTGDYKPFSYRDPD------GQYTGFDIDVAKSLAKSLGVKVEFVPT-------- 69 Query: 478 DPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPG 537 W ++ +L + DIA+ +T+T R++ DFS P+M+ G + +++K K Sbjct: 70 -----TWPTLMSDLQADKFDIAMGGVTVTPERQKKADFSDPYMTFGKTPLVRKEDADKFK 124 Query: 538 VFSFLD 543 ++ Sbjct: 125 SLEDIN 130 >3K4U-A nrPDB Length = 245 Score = 95.6 bits (236), Expect = 8e-20, Method: Composition-based stats. Identities = 34/146 (23%), Positives = 64/146 (43%), Gaps = 13/146 (8%) Query: 437 EQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRA 496 E + G+ VDLA E+AK + +K KL W+G++ LV + Sbjct: 19 EMKDKKGNVIGFDVDLAREMAKAMGVKLKLVPTS-------------WDGLIPGLVTEKF 65 Query: 497 DIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFA 556 DI ++ +TI+ R ++F +P++ +G S+++KK + + LD + + Sbjct: 66 DIIISGMTISQERNLRVNFVEPYIVVGQSLLVKKGLEKGVKSYKDLDKPELTLVTKFGVS 125 Query: 557 YIGVSVVLFLVSRFSPYEWHLEDNNE 582 + LF ++ Y+ E E Sbjct: 126 AEYAAKRLFKNAKLKTYDTEAEAVQE 151 Score = 40.1 bits (92), Expect = 0.004, Method: Composition-based stats. Identities = 30/165 (18%), Positives = 62/165 (37%), Gaps = 24/165 (14%) Query: 638 IISSYTANLAAFLTVERMVSPIESAEDLAKQTEI----AYGTLDSGSTKEFFRRSKIAVY 693 + Y + L + + ++S +DL + E+ +G + K F+ +K+ Y Sbjct: 84 FVEPYIVVGQSLLVKKGLEKGVKSYKDL-DKPELTLVTKFGVSAEYAAKRLFKNAKLKTY 142 Query: 694 EKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMN-EYIEQRKPCDTMKVGGN 752 + T A+ V V K F+ + N ++ Q+ + + + Sbjct: 143 D----------------TEAEAVQEVLNGKADM-FIFDLPFNVAFMAQKGQGYLVHLDTS 185 Query: 753 LDSKGYGVATPKGSA-LRTPVNLAVLKLSEQGILDKLKNKWWYDK 796 L + G A KG +N + ++ G D+L +W+ D Sbjct: 186 LTYEPLGWAIKKGDPDFLNWLNHFLAQIKHDGSYDELYERWFVDT 230 >4IO3-A nrPDB Length = 248 Score = 90.6 bits (223), Expect = 3e-18, Method: Composition-based stats. Identities = 33/150 (22%), Positives = 57/150 (38%), Gaps = 10/150 (6%) Query: 651 TVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTK 710 + R + I+ +DL K +I Y + R + + K Sbjct: 109 ILMRKGTLIDGMDDL-KNGKIPYNRIG-------IRIGTAGEDYYLREISGGSRNFYPLK 160 Query: 711 TTADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRT 770 + + + +F ++ EY+ C+ VG + D +G+ TPK Sbjct: 161 SRQEMYDSLLAGIIDVSF-MDIGTAEYVTNNIYCNLTLVGEDFDKSTFGIVTPKEWLYAK 219 Query: 771 PVNLAVLKLSEQGILDKLKNKWWYDKGECG 800 +++ +L L E GILD LK KW+ K C Sbjct: 220 DLDVNILSLRETGILDNLKKKWFQTKA-CP 248 Score = 64.8 bits (156), Expect = 2e-10, Method: Composition-based stats. Identities = 27/137 (19%), Positives = 53/137 (38%), Gaps = 15/137 (10%) Query: 411 SSSSENRTIVVTTILESPYVMYKKNHEQLEGNE-RYEGYCVDLAYEIAKHVRIKYKLSIV 469 S+ + T+ + I P+ + + N + GY +DL + + + + Sbjct: 2 SARLKGITLRIGVIESVPFTIVANVIDTSGRNTTKLTGYVLDLIEYLRDKMGFVADVQLA 61 Query: 470 GDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIK 529 P + G+V L G DIA+ +T+T R E++ FS + I+++ Sbjct: 62 ---------PPNTSYTGLVLALANGDYDIAIGDITVTSARREIVAFSNSISDNSMRILMR 112 Query: 530 KPQKSKPGVFSFLDPLA 546 K + +D L Sbjct: 113 KG-----TLIDGMDDLK 124 >1GGG-A nrPDB Length = 226 Score = 90.6 bits (223), Expect = 3e-18, Method: Composition-based stats. Identities = 27/104 (25%), Positives = 49/104 (47%), Gaps = 13/104 (12%) Query: 438 QLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRAD 497 + + + Y G+ VDL IAK +++ Y+L + ++G++ L D Sbjct: 17 EFKQGDLYVGFDVDLWAAIAKELKLDYELKPMD-------------FSGIIPALQTKNVD 63 Query: 498 IAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSF 541 +A+A +TIT R++ IDFS + G+ +M+K V Sbjct: 64 LALAGITITDERKKAIDFSDGYYKSGLLVMVKANNNDVKSVKDL 107 Score = 43.6 bits (101), Expect = 3e-04, Method: Composition-based stats. Identities = 23/70 (32%), Positives = 36/70 (51%), Gaps = 2/70 (2%) Query: 726 FAFLLESTMNEYIEQRKP-CDTMKVGGNLDSKGYGVATPKGSA-LRTPVNLAVLKLSEQG 783 A L ++ Y + VG +L+++ YG+A PKGS LR VN A+ L E G Sbjct: 152 DAVLHDTPNILYFIKTAGNGQFKAVGDSLEAQQYGIAFPKGSDELRDKVNGALKTLRENG 211 Query: 784 ILDKLKNKWW 793 +++ KW+ Sbjct: 212 TYNEIYKKWF 221 >4F3P-A nrPDB Length = 249 Score = 89.1 bits (219), Expect = 8e-18, Method: Composition-based stats. Identities = 30/146 (20%), Positives = 62/146 (42%), Gaps = 21/146 (14%) Query: 438 QLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRAD 497 + + ++Y G+ +DL EIAK YK+ + + G++ L D Sbjct: 38 EFKQGDKYVGFDLDLWAEIAKGAGWTYKIQPMD-------------FAGLIPALQTQNID 84 Query: 498 IAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAY 557 +A++ +TI R + IDFS P+ G++ M++ + L+ ++ A Sbjct: 85 VALSGMTIKEERRKAIDFSDPYYDSGLAAMVQANNTT-IKSIDDLN-------GKVIAAK 136 Query: 558 IGVSVVLFLVSRFSPYEWHLEDNNEE 583 G + + ++ + P E N ++ Sbjct: 137 TGTATIDWIKAHLKPKEIRQFPNIDQ 162 Score = 45.5 bits (106), Expect = 1e-04, Method: Composition-based stats. Identities = 33/153 (21%), Positives = 60/153 (39%), Gaps = 19/153 (12%) Query: 642 YTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMK 701 Y + LAA V+ + I+S +DL G + + T A + + +++K Sbjct: 107 YDSGLAA--MVQANNTTIKSIDDLN-------GKVIAAKT-------GTATIDWIKAHLK 150 Query: 702 SAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKV-GGNLDSKGYGV 760 E F D ++ A + ++ + + +KV G + YG+ Sbjct: 151 PKEIRQF--PNIDQAYLALEAGRVDAAMHDTPNVLFFVNNEGKGRVKVAGAPVSGDKYGI 208 Query: 761 ATPKGSALRTPVNLAVLKLSEQGILDKLKNKWW 793 PKGS L VN + ++ G K+ KW+ Sbjct: 209 GFPKGSPLVAKVNAELARMKADGRYAKIYKKWF 241 >4F3S-A nrPDB Length = 255 Score = 85.2 bits (209), Expect = 1e-16, Method: Composition-based stats. Identities = 29/109 (26%), Positives = 54/109 (49%), Gaps = 23/109 (21%) Query: 414 SENRTIVVTTILESPYVMYKKNHEQLEGNER--YEGYCVDLAYEIAKHVRIKYKLSIVGD 471 E RT+ V SP +++K +L+G + + YC ++H ++ Sbjct: 6 VEGRTLNVAVSPASPPMLFKSADGKLQGIDLELFSSYCQ------SRHCKL--------- 50 Query: 472 GKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFM 520 + W+GM+G + G+AD+A + ++IT R++VIDFS+P+ Sbjct: 51 ------NITEYAWDGMLGAVASGQADVAFSGISITDKRKKVIDFSEPYY 93 Score = 31.7 bits (70), Expect = 1.7, Method: Composition-based stats. Identities = 22/77 (28%), Positives = 35/77 (45%), Gaps = 6/77 (7%) Query: 708 FTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRK-PCDTMKVGGNLDSKGYGVATPKGS 766 T + +A ++ AF+ E + ++K P ++ V N+D G+A KGS Sbjct: 149 LYPTYNETMADLKNGNLDLAFIEEPVYFTFKNKKKMPIESRYVFKNVDQ--LGIAFKKGS 206 Query: 767 ALRTPVNLAVLKLSEQG 783 +R N L L EQG Sbjct: 207 PVRDDFN---LWLKEQG 220 >4YMX-A nrPDB Length = 260 Score = 79.0 bits (193), Expect = 7e-15, Method: Composition-based stats. Identities = 29/124 (23%), Positives = 54/124 (43%), Gaps = 18/124 (14%) Query: 419 IVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARD 478 IV+ T + P + H+ G + G+ +D+A IAK + +K ++ Sbjct: 39 IVMGTSADFPPFEF---HKVEGGKDEIVGFDIDIANAIAKKLGVKLEIK----------- 84 Query: 479 PETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGV 538 + G++ L GR D+ +A +T T R++ +DFS + +++K S Sbjct: 85 --DMDFKGLIPALQAGRVDMVIAGMTPTAERKKSVDFSDLYYDSRQVVVVK--NDSPISK 140 Query: 539 FSFL 542 F L Sbjct: 141 FDDL 144 Score = 34.7 bits (78), Expect = 0.19, Method: Composition-based stats. Identities = 32/148 (21%), Positives = 52/148 (35%), Gaps = 18/148 (12%) Query: 650 LTVERMVSPIESAEDLAKQT-EIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVF 708 + V + SPI +DL +T + GT + K+ + +M Sbjct: 129 VVVVKNDSPISKFDDLKVKTIAVQIGTTSEEAAKKIPNVKLKQLNRVSDEFMDLQNGRCD 188 Query: 709 TKTTADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGS-A 767 D VA+ + K +L +E G VA KG+ + Sbjct: 189 AIVVEDTVAKAYLKEYKDMKILYMDEINNVEN----------------GSAVAVAKGNKS 232 Query: 768 LRTPVNLAVLKLSEQGILDKLKNKWWYD 795 L VN + +L + G DKL +KW+ Sbjct: 233 LLDVVNEVIKELKQSGEYDKLVDKWFKQ 260 >2Q2A-A nrPDB Length = 272 Score = 77.9 bits (190), Expect = 2e-14, Method: Composition-based stats. Identities = 22/99 (22%), Positives = 41/99 (41%), Gaps = 13/99 (13%) Query: 441 GNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAV 500 + G+ VDL + K + Y+L +G W+ + L D+ + Sbjct: 59 QKGKIVGFDVDLLDAVMKAAGLDYELKNIG-------------WDPLFASLQSKEVDMGI 105 Query: 501 APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVF 539 + +TIT R++ DFS P+ I++K+ K + Sbjct: 106 SGITITDERKQSYDFSDPYFEATQVILVKQGSPVKNALD 144 Score = 48.6 bits (114), Expect = 1e-05, Method: Composition-based stats. Identities = 30/151 (19%), Positives = 62/151 (41%), Gaps = 20/151 (13%) Query: 647 AAFLTVERMVSPIESAEDLAKQT-EIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEP 705 A + + + SP+++A DL +T + T + ++ F + ++K E Sbjct: 127 ATQVILVKQGSPVKNALDLKGKTIGVQNATTGQEAAEKLFGKGP---------HIKKFET 177 Query: 706 SVFTKTTADGVARVRKSKGKFAFLLESTM-NEYIEQRKPCDTMKVG--GNLDSKGYGVAT 762 +V + G A + ++ + NEY++ + N S+ YG+ Sbjct: 178 TVV-------AIMELLNGGVDAVITDNAVANEYVKNNPNKKLQVIEDPKNFASEYYGMIF 230 Query: 763 PKGSALRTPVNLAVLKLSEQGILDKLKNKWW 793 PK S L+ V+ A+ + G ++ KW+ Sbjct: 231 PKNSELKAKVDEALKNVINSGKYTEIYKKWF 261 >4H5F-A nrPDB Length = 243 Score = 74.8 bits (182), Expect = 1e-13, Method: Composition-based stats. Identities = 31/126 (24%), Positives = 60/126 (47%), Gaps = 18/126 (14%) Query: 419 IVVTTILE-SPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGAR 477 +VV T + +P+ + ++G + G +D+A IA + +K ++ Sbjct: 14 LVVATSPDYAPF----EFQSLVDGKNQVVGADIDMAQAIADELGVKLEI----------- 58 Query: 478 DPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPG 537 + ++ ++ L G+AD+AVA ++ T R+EV DFS P+ IS ++ K K Sbjct: 59 --LSMSFDNVLTSLQTGKADLAVAGISATDERKEVFDFSIPYYENKISFLVHKADVEKYK 116 Query: 538 VFSFLD 543 + L+ Sbjct: 117 DLTSLE 122 >4G4P-A nrPDB Length = 244 Score = 74.0 bits (180), Expect = 3e-13, Method: Composition-based stats. Identities = 36/172 (20%), Positives = 66/172 (38%), Gaps = 29/172 (16%) Query: 413 SSENRTIVVTTILE-SPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGD 471 E + + T L +P+ E + +Y G VDL IAK + L +G Sbjct: 19 GMEGKKYTIGTDLTFAPF-------EFQDSKGKYIGIDVDLLDAIAKDQDFEVDLKPLG- 70 Query: 472 GKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKP 531 ++ V + + D +A ++IT R++ DFS P+ G+ + +KK Sbjct: 71 ------------FDSAVQAIQSKQIDGMIAGMSITDERKKSFDFSDPYFDSGLQLAVKKG 118 Query: 532 QKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEE 583 K + L V A +G FL Y++ +++ ++ Sbjct: 119 N-DKIKSYDDL-------KGKTVAAKVGTESANFLEKNKEKYDYTIKNFDDA 162 Score = 33.6 bits (75), Expect = 0.44, Method: Composition-based stats. Identities = 28/146 (19%), Positives = 49/146 (33%), Gaps = 17/146 (11%) Query: 650 LTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFT 709 L V++ I+S +DL +T G+ F Y+ ++ Sbjct: 113 LAVKKGNDKIKSYDDLKGKTV----AAKVGTESANFLEKNKEKYDY----------TIKN 158 Query: 710 KTTADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGS--A 767 A G+ + ++ A + + + Y + VG YG A KG Sbjct: 159 FDDATGLYKALENGEADAIVDDYPVLGY-AVKNGQKLQLVGDKETGSSYGFAVKKGQNPE 217 Query: 768 LRTPVNLAVLKLSEQGILDKLKNKWW 793 L N + L + G DK+ N + Sbjct: 218 LIKKFNAGLKNLKDNGTYDKILNNYL 243 >4ZEF-A nrPDB Length = 251 Score = 72.1 bits (175), Expect = 9e-13, Method: Composition-based stats. Identities = 32/124 (25%), Positives = 48/124 (38%), Gaps = 18/124 (14%) Query: 423 TILESPYVMYKKNH----EQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARD 478 T + YV+ + E Y G VDL A+ + +G Sbjct: 24 TPKKEKYVIASDSTFAPFEFQNAQGDYVGIDVDLVKRAAELQGFTVEFKFIG-------- 75 Query: 479 PETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGV 538 ++ V + G+AD VA +TIT R++ DFS P+ GI I +KK K Sbjct: 76 -----FSSAVQAVESGQADGMVAGMTITDDRKKAFDFSVPYFDSGIQIAVKKGN-DKIKS 129 Query: 539 FSFL 542 + L Sbjct: 130 YDDL 133 >4I62-A nrPDB Length = 269 Score = 70.6 bits (171), Expect = 3e-12, Method: Composition-based stats. Identities = 22/111 (19%), Positives = 53/111 (47%), Gaps = 13/111 (11%) Query: 434 KNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVY 493 + + ++G + G ++LA IA + ++ +LS + ++ ++ + Sbjct: 53 EYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMS-------------FDNVLASVQS 99 Query: 494 GRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDP 544 G+AD+A++ ++ T R +V DFS P+ + +++KK + + L Sbjct: 100 GKADLAISGVSKTDERSKVFDFSTPYYTAKNKLIVKKSDLATYQSVNDLAQ 150 Score = 34.4 bits (77), Expect = 0.24, Method: Composition-based stats. Identities = 32/134 (23%), Positives = 50/134 (37%), Gaps = 23/134 (17%) Query: 660 ESAEDLA-KQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVAR 718 +S DLA K+ G++ K+ + S + K ++ T Sbjct: 143 QSVNDLAQKKVGAQKGSIQETMAKDLLQNSSLVSLPK--------NGNLITD-------- 186 Query: 719 VRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSK---GYGVATPKGSA-LRTPVNL 774 KS A + E + + + P D N + + Y VA K S L+ V+ Sbjct: 187 -LKSGQVDAVIFEEPVAKGFVENNP-DLAIADLNFEKEQDDSYAVAMKKDSKELKEAVDK 244 Query: 775 AVLKLSEQGILDKL 788 + KL E G LDKL Sbjct: 245 TIQKLKESGELDKL 258 >2PYY-A nrPDB Length = 228 Score = 69.8 bits (169), Expect = 5e-12, Method: Composition-based stats. Identities = 23/96 (23%), Positives = 41/96 (42%), Gaps = 1/96 (1%) Query: 699 YMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRKP-CDTMKVGGNLDSKG 757 Y++ SV + + ++K A + ++ + + + VG L + Sbjct: 126 YLREHHISVLEVPKIEEAYKALQTKKADAVVFDAPVLLFYAANEGKGKVEIVGSILREES 185 Query: 758 YGVATPKGSALRTPVNLAVLKLSEQGILDKLKNKWW 793 YG+ P S R P+N A+L L E G L +KW+ Sbjct: 186 YGIILPNNSPYRKPINQALLNLKENGTYQSLYDKWF 221 Score = 63.3 bits (152), Expect = 4e-10, Method: Composition-based stats. Identities = 26/111 (23%), Positives = 50/111 (45%), Gaps = 20/111 (18%) Query: 419 IVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARD 478 ++V T + P+V L G+ +DL IA + I+ KL +Y + Sbjct: 5 LLVATRVIPPFV--------LSNKGELSGFSIDLWRSIATQIGIESKLI-----EYSSVP 51 Query: 479 PETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIK 529 ++ + + ++ +A ++IT RE+ DFS P + G+ IM++ Sbjct: 52 E-------LISAIKDNKVNLGIAAISITAEREQNFDFSLPIFASGLQIMVR 95 >5HPQ-A nrPDB Length = 255 Score = 66.3 bits (160), Expect = 5e-11, Method: Composition-based stats. Identities = 24/131 (18%), Positives = 51/131 (38%), Gaps = 19/131 (14%) Query: 414 SENRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGK 473 E+ + V T + Y+ Y G+ VD+A +A+ + K + Sbjct: 20 LESGVLRVATTGDYKPFSYRTEEGG------YAGFDVDMAQRLAESLGAKLVVVPTS--- 70 Query: 474 YGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQK 533 W ++ + R DIA++ ++I L R+ FS P++ G + + ++ Sbjct: 71 ----------WPNLMRDFADDRFDIAMSGISINLERQRQAYFSIPYLRDGKTPITLCSEE 120 Query: 534 SKPGVFSFLDP 544 ++ +D Sbjct: 121 ARFQTLEQIDQ 131 >2IEE-A nrPDB Length = 271 Score = 64.8 bits (156), Expect = 2e-10, Method: Composition-based stats. Identities = 28/146 (19%), Positives = 55/146 (37%), Gaps = 17/146 (11%) Query: 397 ERFVPFSDQQISNDSSSSENRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEI 456 + + + + +V T+ P H+ G+++ GY V++ E Sbjct: 2 SGKNEADSKDTGWEQIKDKGKIVVATSGTLYP----TSYHDTDSGSDKLTGYEVEVVREA 57 Query: 457 AKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFS 516 AK + +K + +G +GM+ + G+ D A + +T REE FS Sbjct: 58 AKRLGLKVEFKEMGI-------------DGMLTAVNSGQVDAAANDIDVTKDREEKFAFS 104 Query: 517 KPFMSLGISIMIKKPQKSKPGVFSFL 542 P+ + +++K S L Sbjct: 105 TPYKYSYGTAIVRKDDLSGIKTLKDL 130 >5EYF-A nrPDB Length = 245 Score = 63.3 bits (152), Expect = 4e-10, Method: Composition-based stats. Identities = 25/98 (25%), Positives = 46/98 (46%), Gaps = 12/98 (12%) Query: 446 EGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTI 505 +G+ VD+A I K + + +GK + +K + L G D +A +TI Sbjct: 39 QGFDVDIAKAITKKI-------LGDNGKTEFVEVTSKT---RIPLLKNGNIDAIIATMTI 88 Query: 506 TLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLD 543 T R++ +DFS + G ++++KK S+ L+ Sbjct: 89 TDERKKQVDFSDVYFDAGQALLVKK--GSQIKSVDDLN 124 Score = 51.7 bits (122), Expect = 2e-06, Method: Composition-based stats. Identities = 29/146 (19%), Positives = 57/146 (39%), Gaps = 17/146 (11%) Query: 654 RMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTA 713 + S I+S +DL T + + ++ R+ + + A Sbjct: 112 KKGSQIKSVDDLNASTTVL--AVKGSTSAANIRQHAPDA------------KILELENYA 157 Query: 714 DGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSA-LRTPV 772 + ++ +G A ++ + I P + VGG ++ YG+A KG V Sbjct: 158 EAFTALQSGQGD-AMTTDNAILLGIADENP-EYELVGGTFTNEPYGIAINKGQENFLKAV 215 Query: 773 NLAVLKLSEQGILDKLKNKWWYDKGE 798 N A+ ++ G DK+ KW+ ++ E Sbjct: 216 NQALEEMHADGTYDKIYQKWFPNETE 241 >4OEN-A nrPDB Length = 223 Score = 60.6 bits (145), Expect = 3e-09, Method: Composition-based stats. Identities = 26/149 (17%), Positives = 55/149 (36%), Gaps = 29/149 (19%) Query: 427 SPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNG 486 +P+V ++ +Y G ++L IAK + ++ ++ Sbjct: 14 APFVFQNSSN-------QYTGIDMELIKAIAKDQGFEIEI-------------TNPGFDA 53 Query: 487 MVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLA 546 + + G+AD +A +++T R+ DFS+ + + + +K + S + L Sbjct: 54 AISAVQAGQADGIIAGMSVTDARKATFDFSESYYTANTILGVK--ESSNIASYEDL---- 107 Query: 547 YEIWMCIVFAYIGVSVVLFLVSRFSPYEW 575 V G + FL S Y + Sbjct: 108 ---KGKTVGVKNGTASQTFLTENQSKYGY 133 >4KPT-A nrPDB Length = 251 Score = 59.8 bits (143), Expect = 5e-09, Method: Composition-based stats. Identities = 32/123 (26%), Positives = 54/123 (43%), Gaps = 23/123 (18%) Query: 437 EQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRA 496 E G +++ G VD+ E+AK K ++S G ++ + L G+ Sbjct: 42 EFQNGQKKWVGIDVDIMQEVAKINDWKLEMSYPG-------------FDAALQNLKAGQV 88 Query: 497 DIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFL--------DPLAYE 548 D +A +TIT R+E DFS P+ + ++I K SK +S L + A + Sbjct: 89 DGIIAGMTITDERKETFDFSNPYYTSALTIATTKD--SKLSDYSDLKGKAVGAKNGTAAQ 146 Query: 549 IWM 551 W+ Sbjct: 147 TWL 149 >5LOM-A nrPDB Length = 269 Score = 59.4 bits (142), Expect = 6e-09, Method: Composition-based stats. Identities = 23/137 (16%), Positives = 55/137 (40%), Gaps = 17/137 (12%) Query: 398 RFVPFSDQQISNDSSSSENRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIA 457 VP + N + TI V T+ ++ + + G+ ++L +A Sbjct: 13 GLVP-RGSHMDNPLGLIDPTTISVGTMGDAKPYAFTTAD------GNFTGFDIELFLNVA 65 Query: 458 KHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSK 517 + K + + + ++ ++ + GR D+A A + T R+E +DFS Sbjct: 66 GRLGFKKEQVVF----------TGQEFSALMPSVANGRFDVAAAAIGTTAKRKETVDFSD 115 Query: 518 PFMSLGISIMIKKPQKS 534 +++ +S++ + + Sbjct: 116 GYLAGFLSVLTSEAGIT 132 Score = 33.2 bits (74), Expect = 0.54, Method: Composition-based stats. Identities = 30/153 (19%), Positives = 50/153 (32%), Gaps = 19/153 (12%) Query: 646 LAAFLTVERMVSPIESAEDLA-KQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAE 704 LA FL+V + I A L K+ + GTL ++ F + + + Sbjct: 118 LAGFLSVLTSEAGITDAAGLKGKRLGVVQGTLQEIYAEKNFAGTDLVKFPD--------- 168 Query: 705 PSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPK 764 V+ + FL +Y R P + V G K Sbjct: 169 -------NNSAVSALNNGTVDAHFLDFEAAKDY-SARYPALKIAVNIPSFDAPAGFVIRK 220 Query: 765 GSA-LRTPVNLAVLKLSEQGILDKLKNKWWYDK 796 G+ LR ++ + + + G KL KW+ Sbjct: 221 GNDALRNALDKGLKEAMQDGTWKKLHEKWFPGT 253 >6FXG-A nrPDB Length = 227 Score = 59.4 bits (142), Expect = 6e-09, Method: Composition-based stats. Identities = 32/123 (26%), Positives = 54/123 (43%), Gaps = 23/123 (18%) Query: 437 EQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRA 496 E G +++ G VD+ E+AK K ++S G ++ + L G+ Sbjct: 18 EFQNGQKKWVGIDVDIMQEVAKINDWKLEMSYPG-------------FDAALQNLKAGQV 64 Query: 497 DIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFL--------DPLAYE 548 D +A +TIT R+E DFS P+ + ++I K SK +S L + A + Sbjct: 65 DGIIAGMTITDERKETFDFSNPYYTSALTIATTKD--SKLSDYSDLKGKAVGAKNGTAAQ 122 Query: 549 IWM 551 W+ Sbjct: 123 TWL 125 >5OTA-A nrPDB Length = 265 Score = 58.6 bits (140), Expect = 1e-08, Method: Composition-based stats. Identities = 21/94 (22%), Positives = 42/94 (44%), Gaps = 13/94 (13%) Query: 440 EGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIA 499 + + G+ +DL ++ K + I+ K + W+G++ L GR D Sbjct: 22 DAGGKLIGFDIDLGNDLCKRMNIECKFV-------------EQAWDGIIPSLTAGRYDAI 68 Query: 500 VAPLTITLVREEVIDFSKPFMSLGISIMIKKPQK 533 +A + I RE+VI FS+P++ ++ + Sbjct: 69 MAAMGIQPAREKVIAFSRPYLLTPMTFLTTADSP 102 >3TQL-A nrPDB Length = 227 Score = 57.5 bits (137), Expect = 2e-08, Method: Composition-based stats. Identities = 19/106 (17%), Positives = 40/106 (37%), Gaps = 20/106 (18%) Query: 428 PYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGM 487 PYV + + EG+ D+ + K ++ + W+ + Sbjct: 14 PYVYMGPS-------GQVEGFGADIVKAVCKQMQ-------------AVCTISNQPWDSL 53 Query: 488 VGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQK 533 + L G+ D + IT R++ +DF+ P+ + +S + K Sbjct: 54 IPSLKLGKFDALFGGMNITTARQKEVDFTDPYYTNSVSFIADKNTP 99 >2Y7I-A nrPDB Length = 229 Score = 55.9 bits (133), Expect = 7e-08, Method: Composition-based stats. Identities = 22/118 (18%), Positives = 53/118 (44%), Gaps = 22/118 (18%) Query: 412 SSSENRTIVVTTILE-SPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVG 470 +S RT+ T +PY E ++ + + G+ +D+A + K ++ + Sbjct: 1 ASVSARTLHFGTSATYAPY-------EFVDADNKIVGFDIDVANAVCKEMQAECSF---- 49 Query: 471 DGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMI 528 + ++ ++ L + + D +A + +T RE+ + FS+P+ G+S ++ Sbjct: 50 ---------TNQSFDSLIPSLRFKKFDAVIAGMDMTPKREQQVSFSQPYYE-GLSAVV 97 >5ORE-A nrPDB Length = 263 Score = 55.5 bits (132), Expect = 8e-08, Method: Composition-based stats. Identities = 18/80 (22%), Positives = 39/80 (48%), Gaps = 13/80 (16%) Query: 440 EGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIA 499 + +G+ +DLA + + ++ K ++ + W+G++ L + D Sbjct: 21 GPGGKLDGFEIDLANALCEKMKAKCQIV-------------AQNWDGIMPSLTGKKYDAI 67 Query: 500 VAPLTITLVREEVIDFSKPF 519 +A +++T R+EVI FS P+ Sbjct: 68 MAAMSVTPKRQEVIGFSIPY 87 Score = 32.1 bits (71), Expect = 1.2, Method: Composition-based stats. Identities = 21/80 (26%), Positives = 33/80 (41%), Gaps = 5/80 (6%) Query: 720 RKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKG-YGV---ATPK-GSALRTPVNL 774 S A L +T+ ++ K+ G L S G +GV K +AL+ + Sbjct: 172 LTSGRLDAVLANATVLAAAIEKPEMKGAKLVGPLFSGGEFGVVAVGLRKEDTALKADFDA 231 Query: 775 AVLKLSEQGILDKLKNKWWY 794 A+ SE G + L KW+ Sbjct: 232 AIKAASEDGTIKTLSLKWFK 251 >3VV5-A nrPDB Length = 260 Score = 54.8 bits (130), Expect = 1e-07, Method: Composition-based stats. Identities = 21/95 (22%), Positives = 38/95 (40%), Gaps = 13/95 (13%) Query: 439 LEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADI 498 + + G+ VDL IA+ + +K + ++ ++ +L GR D Sbjct: 52 FDERNQLTGFEVDLGNAIAERLGLK-------------PRWIAQSFDTLLIQLNQGRFDF 98 Query: 499 AVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQK 533 +A IT R +DF+ P G I+ +K Sbjct: 99 VIASHGITEERARAVDFTNPHYCTGGVIVSRKGGP 133 Score = 34.0 bits (76), Expect = 0.29, Method: Composition-based stats. Identities = 18/65 (27%), Positives = 36/65 (55%), Gaps = 1/65 (1%) Query: 736 EYIEQRKPCDTMKVGGNLDSKGYGVATPKGS-ALRTPVNLAVLKLSEQGILDKLKNKWWY 794 E I++RK +T++VG + + +A KG+ +L +N A+ +L + G ++ KW+ Sbjct: 195 EAIKERKLENTLQVGELVFQERVAMAVAKGNKSLLDALNRALAELMQDGTYARISQKWFG 254 Query: 795 DKGEC 799 + C Sbjct: 255 EDVRC 259 >1IIT-A nrPDB Length = 232 Score = 54.0 bits (128), Expect = 3e-07, Method: Composition-based stats. Identities = 23/126 (18%), Positives = 46/126 (36%), Gaps = 19/126 (15%) Query: 419 IVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARD 478 + V + P+V Y + N + G +D+ +A+ + + G Sbjct: 6 LKVGVVGNPPFVFYGE-----GKNAAFTGISLDVWRAVAESQKWNSEYVRQNSISAG--- 57 Query: 479 PETKIWNGMVGELVYGRADIAVAPLTITLVREEV--IDFSKPFMSLGISIMIKKPQKSKP 536 + + G DI + P+++T R + I F++P+ S GI ++I Sbjct: 58 ---------ITAVAEGELDILIGPISVTPERAAIEGITFTQPYFSSGIGLLIPGTATPLF 108 Query: 537 GVFSFL 542 L Sbjct: 109 RSVGDL 114 Score = 35.1 bits (79), Expect = 0.13, Method: Composition-based stats. Identities = 13/91 (14%), Positives = 32/91 (35%), Gaps = 1/91 (1%) Query: 704 EPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRKP-CDTMKVGGNLDSKGYGVAT 762 + V + + K A + + Y ++ P + + + YG Sbjct: 135 QADVRETNNLTAAITLLQKKQVEAVMFDRPALIYYTRQNPNLNLEVTEIRVSLEPYGFVL 194 Query: 763 PKGSALRTPVNLAVLKLSEQGILDKLKNKWW 793 + S L+ +N+ +L L ++ + +W Sbjct: 195 KENSPLQKTINVEMLNLLYSRVIAEFTERWL 225 >4KQP-A nrPDB Length = 232 Score = 54.0 bits (128), Expect = 3e-07, Method: Composition-based stats. Identities = 23/93 (24%), Positives = 42/93 (45%), Gaps = 13/93 (13%) Query: 442 NERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVA 501 ++++ G VDL IAK+ K K + +G + V + G AD ++ Sbjct: 27 DKQFTGIDVDLLNAIAKNQGFKLKWNFIG-------------FQAAVDSVQSGHADGMMS 73 Query: 502 PLTITLVREEVIDFSKPFMSLGISIMIKKPQKS 534 ++IT R++V D+ P+ S ++I S Sbjct: 74 GMSITDARKQVFDYGSPYYSSNLTIATSSTDDS 106 >3I6V-A nrPDB Length = 232 Score = 54.0 bits (128), Expect = 3e-07, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 34/74 (45%), Gaps = 13/74 (17%) Query: 447 GYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTIT 506 G+ +L E+ K + + W+ ++ LV G D +A ++IT Sbjct: 29 GFERELGDELCKRAGLTCEWV-------------KNDWDSIIPNLVSGNYDTIIAGMSIT 75 Query: 507 LVREEVIDFSKPFM 520 R+EVIDF++ ++ Sbjct: 76 DERDEVIDFTQNYI 89 Score = 37.1 bits (84), Expect = 0.033, Method: Composition-based stats. Identities = 29/160 (18%), Positives = 57/160 (35%), Gaps = 6/160 (3%) Query: 637 IIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKM 696 ++ +Y +A + I+ ++ T +Y G+ ++ A + Sbjct: 60 LVSGNYDTIIAGMSITDERDEVIDFTQNYIPPTASSYVATSDGADLSGIVAAQTATIQAG 119 Query: 697 WSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSK 756 + +S V T + +A VR + F + I + M VG ++ Sbjct: 120 Y-IAESGATLVEFATPEETIAAVRNGEADAVFA-DRDYLVPIVAESGGELMFVGDDVPLG 177 Query: 757 GYGVAT---PKGSALRTPVNLAVLKLSEQGILDKLKNKWW 793 G GV LR + A+ + E G L+ + KW+ Sbjct: 178 G-GVGMGLRESDGELRGKFDAAITSMKEDGTLNTMIKKWF 216 >5X2M-A nrPDB Length = 461 Score = 52.1 bits (123), Expect = 1e-06, Method: Composition-based stats. Identities = 62/420 (14%), Positives = 125/420 (29%), Gaps = 75/420 (17%) Query: 45 FRFAVQLYNTNQNTTEKPFHLNYH-VDHLDSSNSFSVTNAFCSQ---------FSRGV-- 92 RF+V+ N N ++ L Y DH +SF S S G+ Sbjct: 55 MRFSVEEIN-NSSSLLPNVSLGYQMFDHCSDIHSFPGIFKLLSVNDLIRPWEDASTGLPN 113 Query: 93 -YAIFGFYDQMSMNTLTSFCGALHTSFVTPSFPT-----DADVQFVIQMRPALKG----- 141 + G + ++ F+T FP V + P+ Sbjct: 114 AIGVVGPFTSTHALSIAPI-------FMTNLFPMVSYGCSGSVFSKENLYPSFLRTVHSN 166 Query: 142 -----AILSLLGYYKWEKFVYLY-DTERGFSILQAIMEAAVQNNWQVTARSVGNIKDIQE 195 AI+ ++ + W +LY D + G L+ + + N+ + Sbjct: 167 KDVINAIVGIILNFNWRWVAFLYSDDDFGKDGLEQFKNKIEDSEICLAFYKAINVNT--D 224 Query: 196 FRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANLGFTDIVLERVM 255 + ++ ++++ + K ++ ++E V L ++ + +A+ G++ M Sbjct: 225 YLQVFKQIEEQNIKVIVVFAPKVYAEAVVESAVQLNVTNKVW---IADDGWSLNKKLPSM 281 Query: 256 HGGANITGF--------QIVNNENPMVQQFIQRWVRLDEREFPEAKNAPLKYTSAL---- 303 +G NI I + + Q E++ + S Sbjct: 282 NGIQNIGTVLGVAQPVVTIPGFTDFIYSAISQTDGGDTEQKMFCNQKCNCSNLSVKSLLN 341 Query: 304 --------THDAILVIAEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMV 355 + A+ IA A R + C N V I LK Sbjct: 342 ADPSFSFPVYAAVYAIAHALHNTL--------RCGSDRCPKNITV---HPHMILEELKKS 390 Query: 356 QVQGMTGNIQFDTYGRRTNYTIDVY--EMKVSGSRKAGYWNEYERFVPFSDQQISNDSSS 413 + +QFD G ++ V + Y + + + +I ++ Sbjct: 391 NFTLLNQTVQFDENGDPKFGSLSVVFWNSSGNAEEVGSYHFQSSIHLSINKTKIKWFTNG 450 >1HSL-A nrPDB Length = 238 Score = 52.1 bits (123), Expect = 1e-06, Method: Composition-based stats. Identities = 21/132 (15%), Positives = 45/132 (34%), Gaps = 21/132 (15%) Query: 443 ERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIAVAP 502 G+ +DLA E+ K + + + ++ L + D ++ Sbjct: 24 GELVGFDIDLAKELCKRINTQCTFV-------------ENPLDALIPSLKAKKIDAIMSS 70 Query: 503 LTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSV 562 L+IT R++ I F+ + +++ K S + P + V G + Sbjct: 71 LSITEKRQQEIAFTDKLYAADSRLVVAKN--------SDIQPTVASLKGKRVGVLQGTTQ 122 Query: 563 VLFLVSRFSPYE 574 F ++P Sbjct: 123 ETFGNEHWAPKG 134 >5OWF-A nrPDB Length = 259 Score = 52.1 bits (123), Expect = 1e-06, Method: Composition-based stats. Identities = 18/102 (17%), Positives = 41/102 (40%), Gaps = 13/102 (12%) Query: 440 EGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNGMVGELVYGRADIA 499 + + G+ +DL E+ K +++K ++ ++ L + D Sbjct: 42 DAKGEFIGFDIDLGNEMCKRMQVK-------------CTWVASDFDALIPSLKAKKIDAI 88 Query: 500 VAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSF 541 ++ L+IT R++ I FS + ++ K +P + S Sbjct: 89 ISSLSITDKRQQEIAFSDKLYAADSRLIAAKGSPIQPTLESL 130 >4F11-A nrPDB Length = 433 Score = 48.6 bits (114), Expect = 1e-05, Method: Composition-based stats. Identities = 50/295 (16%), Positives = 102/295 (34%), Gaps = 31/295 (10%) Query: 120 TPSFPTDADVQFVIQMRPA---LKGAILSLLGYYKWEKFVYLYDTERGFSILQAIMEAAV 176 TP + + P+ + AIL LL +Y+W++ L + FS ++ + V Sbjct: 119 TPVLADKKKYPYFFRTVPSDNAVNPAILKLLKHYQWKRVGTLTQDVQRFSEVRNDL-TGV 177 Query: 177 QNNWQVTARSVGNIKDIQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRG 236 + + + ++++ + L + + + Sbjct: 178 LYGEDIEISDTESFSNDPCTS--VKKLKGNDVRIILGQFDQNMAAKVFCCAYEENMYGSK 235 Query: 237 YHYMLANLGFTDIVLERVMHGGAN------------ITGFQIVNNE---NPMVQQFIQRW 281 Y +++ G+ + +H AN + G+ V+ E + ++ + Sbjct: 236 YQWIIP--GWYEPSWWEQVHTEANSSRCLRKNLLAAMEGYIGVDFEPLSSKQIKTISGKT 293 Query: 282 VRLDEREF--PEAKNAPLKYTSALTHDAILVIAEAFRYLRRQRVDVSRRGSAGDCLANPA 339 + ERE+ + P K+ +D I VIA+ + + + S R Sbjct: 294 PQQYEREYNNKRSGVGPSKF-HGYAYDGIWVIAKTLQR-AMETLHASSRHQRIQDF--NY 349 Query: 340 VPWSQGIDIERALKMVQVQGMTGNIQFDTYGRRTNYTIDVYEMKVSGSRKAGYWN 394 + G I A+ G+TG + F G R TI + + S K G +N Sbjct: 350 TDHTLGRIILNAMNETNFFGVTGQVVF-RNGERMG-TIKFTQFQDSREVKVGEYN 402 >3DEL-B nrPDB Length = 242 Score = 46.3 bits (108), Expect = 5e-05, Method: Composition-based stats. Identities = 22/129 (17%), Positives = 45/129 (34%), Gaps = 22/129 (17%) Query: 410 DSSSSENRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIV 469 + S + +V T P E ++ G+ +DLA EI+ + + Sbjct: 4 EGGDSNSEKFIVGTNATYPPF------EFVDKRGEVVGFDIDLAREISNKLGKTLDVR-- 55 Query: 470 GDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGIS--IM 527 ++ ++ L R D + ++IT R + I P+ I ++ Sbjct: 56 -----------EFSFDALILNLKQHRIDAVITGMSITPSRLKEI-LMIPYYGEEIKHLVL 103 Query: 528 IKKPQKSKP 536 + K + P Sbjct: 104 VFKGENKHP 112 >1YK0-A nrPDB Length = 480 Score = 44.8 bits (104), Expect = 2e-04, Method: Composition-based stats. Identities = 41/295 (13%), Positives = 92/295 (31%), Gaps = 44/295 (14%) Query: 136 RPALKGAILSLLGYYKWEKFVYLYDTER----GFSILQAIMEAAVQNNWQVTARSVGNIK 191 + +L+L ++ W + +Y ++ + L+ + E + + S K Sbjct: 181 YAKMGEMMLALFRHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETK 240 Query: 192 DIQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANL------- 244 D+ + I+ + E+ ++ + I +I+ G S Y + L Sbjct: 241 DL-DLEDIVRNIQ-ASERVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFNIELFNSSSYG 298 Query: 245 -------GFTDIVLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNAPL 297 D ++ +T + V E ++ V + N + Sbjct: 299 DGSWKRGDKHDFEAKQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVEKQGLNMEDYVNMFV 358 Query: 298 KYTSALTHDAILVIAEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQV 357 + HDAIL+ A + R G N Sbjct: 359 EG----FHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNR-----------------TF 397 Query: 358 QGMTGNIQFDTYGRR-TNYTIDVYEMKVSGSRK--AGYWNEYERFVPFSDQQISN 409 +G+ G + D G R ++++ +G+++ Y+ + RF + + Sbjct: 398 EGIAGQVSIDANGDRYGDFSVIAMTDVEAGTQEVIGDYFGKEGRFEMRPNVKYPW 452 >4Q0C-A nrPDB Length = 584 Score = 44.4 bits (103), Expect = 2e-04, Method: Composition-based stats. Identities = 19/117 (16%), Positives = 48/117 (41%), Gaps = 21/117 (17%) Query: 427 SPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDPETKIWNG 486 +P+ +++ +E++ G + + + +++ V + Sbjct: 351 APFTLFRT-------DEQFGGISAAVLQLLQLRTGLDFEIIGVDTVEE------------ 391 Query: 487 MVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLD 543 ++ +L G AD+A L + RE + FS+P++ G+ +++ + P LD Sbjct: 392 LIAKLRSGEADMA-GALFVNSARESFLSFSRPYVRNGM-VIVTRQDPDAPVDADHLD 446 >2Q88-A nrPDB Length = 257 Score = 39.8 bits (91), Expect = 0.006, Method: Composition-based stats. Identities = 25/130 (19%), Positives = 45/130 (34%), Gaps = 21/130 (16%) Query: 420 VVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKYGARDP 479 + E P+ + + G D+A EI K + + + +YGA Sbjct: 16 RIAIANEPPFTAV-------GADGKVSGAAPDVAREIFKRLGVAD--VVASISEYGA--- 63 Query: 480 ETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVF 539 M+ L GR D A L + R + +S+P + + +KK + Sbjct: 64 -------MIPGLQAGRHDAITAGLFMKPERCAAVAYSQPILCDAEAFALKKGNPLGLKSY 116 Query: 540 SFL--DPLAY 547 + +P A Sbjct: 117 KDIADNPDAK 126 >4GNR-A nrPDB Length = 353 Score = 39.0 bits (89), Expect = 0.010, Method: Composition-based stats. Identities = 55/363 (15%), Positives = 113/363 (31%), Gaps = 61/363 (16%) Query: 27 TISIGGLFMRNTV------QEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFSV 80 TI IG F + E + AV N K + + +++ + SV Sbjct: 7 TIKIGFNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASV 66 Query: 81 TNAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSFPTDA-----DVQFVIQM 135 T +Q V A+ G + + ++PS D D F+ Sbjct: 67 TTNLVTQ--SKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTF 124 Query: 136 RPALKGAILS--LLGYYKWEKFVYLYDTERGFSILQAIMEAAVQNNWQVTARSVGN-IKD 192 + + +G I+S + +K V D ++ + + + +++ + + Sbjct: 125 QDSFQGKIISNYVSEKLNAKKVVLYTDNASDYA---KGIAKSFRESYKGEIVADETFVAG 181 Query: 193 IQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKH-----SRGYHYMLANLGFT 247 +F+ + +M + ++ I+ Q +G G++ F Sbjct: 182 DTDFQAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFN----GEEFV 237 Query: 248 DIVLERVMHGGANITGFQIVNNENPMVQQFIQRWV-RLDEREFPEAKNAPLKYTSALTHD 306 I+GF + + F+ + + +E A AL +D Sbjct: 238 QQATAEKASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFA---------ALAYD 288 Query: 307 AILVIAEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNIQF 366 ++ ++A A + + G D LA +G+TG F Sbjct: 289 SVHLVANAAKGAKN-------SGEIKDNLAKTK----------------DFEGVTGQTSF 325 Query: 367 DTY 369 D Sbjct: 326 DAD 328 >4MLC-A nrPDB Length = 356 Score = 37.8 bits (86), Expect = 0.020, Method: Composition-based stats. Identities = 59/360 (16%), Positives = 112/360 (31%), Gaps = 51/360 (14%) Query: 28 ISIGGLFMRNTVQE--HSAFRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFSVTNAFC 85 I IG + ++ + AVQ N + L D + ++ AF Sbjct: 11 IFIGVAWPFASLDDLFAEGLELAVQEINEQGGVQGRKLSLVKADDEAELEKGLAIAQAFA 70 Query: 86 SQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSF--PTDADVQFVIQMR--PALKG 141 + G+ A+ G + S ++P+ P D ++ R P+ + Sbjct: 71 D--NAGIQAVIGHRNSFISIPAASIYDQAGLVMLSPASTSPDLTDHGYIHVFRNIPSDQE 128 Query: 142 AILSLLGYYKWE----KFVYLYDTERGFSILQAIMEAAVQNNWQVTARSVGNIKDIQEFR 197 L Y + +Y D G + A + A I D + Sbjct: 129 IARQLAIYLAEQGHERMVIYYTDDSYGNGLANAFEDYARAQGI--------TIVDRFNYY 180 Query: 198 RIIEEMDRRQEKRYLIDCE-----VERINTILEQVVILGKHSRGYHYMLANLGFTDIVLE 252 +++++R +K + E +V + N + E Sbjct: 181 GNLKDLERLYDKWQAFGMDGIFIAKTATGGGTEFLVDAKSVGIEVPLIAGNSWDALSLTE 240 Query: 253 RVMHGGANITGFQIVNNENPM-VQQFIQRWVRLDEREFPEAKNAPLKYTSALTHDAILVI 311 + + G G + + NP Q +V RE+ + P +A +DA++++ Sbjct: 241 DIENIGMTAEGLLVGSFFNPQRPDSRTQDFVEAFRREYGQ----PPTSYAAAGYDAVILL 296 Query: 312 AEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNIQFDTYGR 371 AEA L + + + G R L +G+ G +FD G Sbjct: 297 AEA---LEKSDLTHPATLAQG----------------LRDL--GPWEGVMGMHRFDGRGD 335 >3A3K-A nrPDB Length = 435 Score = 34.4 bits (77), Expect = 0.21, Method: Composition-based stats. Identities = 34/261 (13%), Positives = 82/261 (31%), Gaps = 43/261 (16%) Query: 176 VQNNWQVTARSVGNIKDIQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSR 235 V+ +T ++ + + RR+ + I + ++ + G Sbjct: 175 VRERLNITVNHQEFVEGDPDHYPKLLRAVRRKGRVIYICSSPDAFRNLMLLALNAGLTGE 234 Query: 236 GYHYMLANLGFTDIVLERVMHGGANITGFQIVNNENPMVQQFIQ--RWVRLDEREFPE-- 291 Y+ +L L+ G ++ + ++ +Q Q + + E + PE Sbjct: 235 D--YVFFHLDVFGQSLKSAQ-GLVPQKPWERGDGQDRSARQAFQAAKIITYKEPDNPEYL 291 Query: 292 -----------------AKNAPLKYTSALTHDAILVIAEAFRYLRRQRVDVSRRGSAGDC 334 ++ A HD +L+ +A Q V+ + Sbjct: 292 EFLKQLKLLADKKFNFTVEDGLKNIIPASFHDGLLLYVQAVTETLAQGGTVTDGENITQR 351 Query: 335 LANPAVPWSQGIDIERALKMVQVQGMTGNIQFDTYGRR-TNYTIDVYEMKVSGSRKAGYW 393 + N + QG+TG ++ D G R T++++ + + R + Sbjct: 352 MWNRS-----------------FQGVTGYLKIDRNGDRDTDFSLWDMDPETGAFRVVLNY 394 Query: 394 NEYER-FVPFSDQQISNDSSS 413 N + + S+ ++ Sbjct: 395 NGTSQELMAVSEHKLYWPLGY 415 >1RHC-A nrPDB Length = 330 Score = 33.6 bits (75), Expect = 0.35, Method: Composition-based stats. Identities = 23/122 (18%), Positives = 41/122 (33%), Gaps = 9/122 (7%) Query: 469 VGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITL---VREEVIDFSKPFMSLGIS 525 VG G+ P T W V R D+ V + + ++ + F + +L + Sbjct: 104 VGAGEAMNEVPVTGEWPS-----VPVRQDMTVEAVKVMRMLWESDKPVTFKGDYFTLDKA 158 Query: 526 IMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPR 585 + KP P FS + P ++ + V+ + E E + Sbjct: 159 FLYTKPDDEVPLYFSGMGPKGAKLAGMYGDHLMTVAAAPSTLKNV-TIPKFEEGAREAGK 217 Query: 586 DP 587 DP Sbjct: 218 DP 219 >4BIM-A nrPDB Length = 746 Score = 32.8 bits (73), Expect = 0.75, Method: Composition-based stats. Identities = 20/107 (18%), Positives = 35/107 (32%), Gaps = 19/107 (17%) Query: 645 NLAAFLTVE--RMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMW----- 697 N+ F + R I S + + E+ S +FF A++ W Sbjct: 203 NIPVFFIQDAIRFPDLIHSVK-PSPDNEVPQAATAHDSAWDFFSSQPSALHTLFWAMSGN 261 Query: 698 ------SYMKSAEPSVFTKTTADGVARV-----RKSKGKFAFLLEST 733 +M F T DG +++ + +GK A + E Sbjct: 262 GIPRSYRHMDGFGIHTFRLVTEDGKSKLVKWHWKTKQGKAALVWEEA 308 >1X87-A nrPDB Length = 551 Score = 32.4 bits (72), Expect = 0.80, Method: Composition-based stats. Identities = 14/70 (20%), Positives = 26/70 (37%) Query: 346 IDIERALKMVQVQGMTGNIQFDTYGRRTNYTIDVYEMKVSGSRKAGYWNEYERFVPFSDQ 405 I A K ++ QG+ I + YG R + + +M G KA + S Sbjct: 387 HWIRMAQKRIKFQGLPARICWLGYGERAKFGKIINDMVAKGELKAPIVIGRDHLDSGSVA 446 Query: 406 QISNDSSSSE 415 + ++ + Sbjct: 447 SPNRETEGMK 456 >2O1M-A nrPDB Length = 258 Score = 32.1 bits (71), Expect = 1.2, Method: Composition-based stats. Identities = 23/129 (17%), Positives = 47/129 (36%), Gaps = 25/129 (19%) Query: 417 RTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHV---RIKYKLSIVGDGK 473 +TI V T + P + + L GY V+L E+ K + + +K Sbjct: 16 QTITVGTGTQFPNICFIDEKGDL------TGYDVELIKELDKRLPHYKFTFK-------- 61 Query: 474 YGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSK-PFMSLGISIMIKKPQ 532 T ++ ++ L + DI + + RE+ F+K + + I + + Sbjct: 62 -------TMEFSNLLVSLGQHKVDIVAHQMEKSKEREKKFLFNKVAYNHFPLKITVLQNN 114 Query: 533 KSKPGVFSF 541 + G+ Sbjct: 115 DTIRGIEDL 123 >2FKN-A nrPDB Length = 552 Score = 30.9 bits (68), Expect = 2.3, Method: Composition-based stats. Identities = 13/69 (18%), Positives = 27/69 (39%) Query: 354 MVQVQGMTGNIQFDTYGRRTNYTIDVYEMKVSGSRKAGYWNEYERFVPFSDQQISNDSSS 413 V QG+ I + YG R + + E+ +G KA + S + ++ + Sbjct: 396 KVTFQGLPSRICWLGYGERKKMGLAINELVRTGELKAPVVIGRDHLDCGSVASPNRETEA 455 Query: 414 SENRTIVVT 422 ++ + V Sbjct: 456 MKDGSDAVG 464 >1R85-A nrPDB Length = 379 Score = 30.9 bits (68), Expect = 2.5, Method: Composition-based stats. Identities = 18/75 (24%), Positives = 30/75 (40%), Gaps = 8/75 (10%) Query: 109 SFCGALHTSFVTPSFPTDADVQFVIQMRPA--LKGAILSL-LGYYKWEKFVY-LYDTERG 164 G H S + +P++A+++ I M A L I L + Y W Y YD Sbjct: 227 PIDGIGHQSHIQIGWPSEAEIEKTINMFAALGLDNQITELDVSMYGWPPRAYPTYDAIPK 286 Query: 165 FSILQAIMEAAVQNN 179 Q ++ A + + Sbjct: 287 ----QKFLDQAARYD 297 >3C04-A nrPDB Length = 463 Score = 30.1 bits (66), Expect = 4.2, Method: Composition-based stats. Identities = 26/133 (19%), Positives = 47/133 (35%), Gaps = 13/133 (9%) Query: 348 IERALKMVQVQGMTGNIQFDTYGRR----TNYTIDVYEMKVSGSRKAGYWNEYERFVPFS 403 ++ + V+ + + FD G R TN +Y ++ + Sbjct: 223 LKDLIAKVKAENADLGLAFDGDGDRVGVVTNTGTIIYPDRLLMLFAKDVVSRNPGADIIF 282 Query: 404 DQQISNDSSSSENRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIK 463 D + + R I + + VM+K H ++ + G LA E++ HV K Sbjct: 283 DVKCTR-------RLIALISGYGGRPVMWKTGHSLIKKKMKETGAL--LAGEMSGHVFFK 333 Query: 464 YKLSIVGDGKYGA 476 + DG Y A Sbjct: 334 ERWFGFDDGIYSA 346 >4DX0-A nrPDB Length = 243 Score = 29.4 bits (64), Expect = 7.5, Method: Composition-based stats. Identities = 19/84 (22%), Positives = 36/84 (42%), Gaps = 2/84 (2%) Query: 642 YTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMK 701 Y A LA ER +E E +AK ++ T++ + ++ I W + Sbjct: 16 YMAKLAE--QAERYEEMVEFMEKVAKTVDVEELTVEERNLLSVAYKNVIGARRASWRIIS 73 Query: 702 SAEPSVFTKTTADGVARVRKSKGK 725 S E ++ D V+ +++ +GK Sbjct: 74 SIEQKEESRGNEDHVSSIKEYRGK 97 >3AXY-C nrPDB Length = 240 Score = 29.0 bits (63), Expect = 9.5, Method: Composition-based stats. Identities = 18/84 (21%), Positives = 34/84 (40%), Gaps = 2/84 (2%) Query: 642 YTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMK 701 Y A LA ER +E E +AK ++ T++ + ++ I W + Sbjct: 13 YMAKLAE--QAERYEEMVEYMEKVAKTVDVEELTVEERNLLSVAYKNVIGARRASWRIVS 70 Query: 702 SAEPSVFTKTTADGVARVRKSKGK 725 S E + + V +++ +GK Sbjct: 71 SIEQKEEGRGNEEHVTLIKEYRGK 94 >3QS1-A nrPDB Length = 336 Score = 29.0 bits (63), Expect = 9.8, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 23/65 (35%), Gaps = 5/65 (7%) Query: 460 VRIKYKLSIVGDGKYGARDPETKIWNGMVG----ELVYGRADIAVAPLTITLVREEVI-D 514 + YK V D ++G+VG +L G D V L E+ + Sbjct: 103 LSFPYKFIEVTDTNGFEPAYTLGQFDGIVGLGWKDLSIGSVDPVVVELKNQNKIEQAVFT 162 Query: 515 FSKPF 519 F PF Sbjct: 163 FYLPF 167 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.125 0.320 Lambda K H 0.267 0.0384 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 29,727,231 Number of Sequences: 36641 Number of extensions: 1095489 Number of successful extensions: 3296 Number of sequences better than 10.0: 85 Number of HSP's better than 10.0 without gapping: 131 Number of HSP's successfully gapped in prelim test: 22 Number of HSP's that attempted gapping in prelim test: 2717 Number of HSP's gapped (non-prelim): 238 length of query: 888 length of database: 10,336,785 effective HSP length: 106 effective length of query: 782 effective length of database: 6,452,839 effective search space: 5046120098 effective search space used: 5046120098 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 63 (29.0 bits)