BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9Z2U0 (248 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5LEZ-C nrPDB 504 e-143 4YA5-C nrPDB 286 7e-78 5FMG-D nrPDB 250 5e-67 6HE5-A nrPDB 213 5e-56 3H4P-A nrPDB 189 9e-49 2KU2-A nrPDB 171 2e-43 5LF0-A nrPDB 169 7e-43 5FMG-B nrPDB 166 7e-42 6J30-C nrPDB 161 3e-40 5GJR-F nrPDB 157 3e-39 2Z5C-C nrPDB 157 4e-39 1G0U-D nrPDB 155 1e-38 5LE5-B nrPDB 154 3e-38 4FZC-A nrPDB 147 5e-36 5T0I-L nrPDB 142 1e-34 5FMG-C nrPDB 138 3e-33 1IRU-A nrPDB 136 7e-33 5FMG-E nrPDB 136 9e-33 5FMG-F nrPDB 133 7e-32 6EPD-G nrPDB 127 5e-30 3NZW-E nrPDB 123 9e-29 5FGG-F nrPDB 121 2e-28 6FVW-g nrPDB 121 2e-28 5L5W-G nrPDB 102 1e-22 5FMG-A nrPDB 102 2e-22 5FMG-G nrPDB 89 2e-18 3H4P-a nrPDB 62 2e-10 6HEC-1 nrPDB 58 4e-09 3IPM-H nrPDB 57 1e-08 3NZW-L nrPDB 55 2e-08 3UNH-H nrPDB 51 4e-07 5FMG-I nrPDB 51 5e-07 6AVO-B nrPDB 48 4e-06 6EPF-2 nrPDB 47 1e-05 5L4G-8 nrPDB 45 2e-05 3NZW-K nrPDB 43 1e-04 5FMG-K nrPDB 42 2e-04 5FGE-J nrPDB 42 2e-04 3WXR-K nrPDB 42 2e-04 6EPF-5 nrPDB 40 7e-04 3UNB-K nrPDB 40 0.001 5CZ8-K nrPDB 40 0.001 5FGI-H nrPDB 40 0.001 5FMG-M nrPDB 40 0.001 5LN3-5 nrPDB 39 0.002 5L64-K nrPDB 35 0.026 5L5A-K nrPDB 35 0.044 5FMG-N nrPDB 34 0.062 6AVO-A nrPDB 31 0.40 3BB7-A nrPDB 31 0.48 5FMG-J nrPDB 31 0.58 3C1M-A nrPDB 30 0.72 5VFT-S nrPDB 30 0.92 5L4G-U nrPDB 30 1.1 6EPF-6 nrPDB 30 1.3 5MPC-h nrPDB 29 1.8 2FV8-A nrPDB 29 1.9 6DTT-A nrPDB 28 2.5 5LF3-J nrPDB 28 5.4 4HO7-A nrPDB 27 6.6 6FAI-j nrPDB 27 7.1 >5LEZ-C nrPDB Length = 248 Score = 504 bits (1297), Expect = e-143, Method: Compositional matrix adjust. Identities = 245/248 (98%), Positives = 247/248 (99%) Query: 1 MSYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVR 60 MSYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRG+DIVVLGVEKKSVAKLQDERTVR Sbjct: 1 MSYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTVR 60 Query: 61 KICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQ 120 KICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQ Sbjct: 61 KICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQ 120 Query: 121 SNGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDA 180 SNGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTD+A Sbjct: 121 SNGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDEA 180 Query: 181 IETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQPLKILNPEEIEKYVAEIEKEKEENE 240 IETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQ LKILNPEEIEKYVAEIEKEKEENE Sbjct: 181 IETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQSLKILNPEEIEKYVAEIEKEKEENE 240 Query: 241 KKKQKKAS 248 KKKQKKAS Sbjct: 241 KKKQKKAS 248 >4YA5-C nrPDB Length = 254 Score = 286 bits (731), Expect = 7e-78, Method: Compositional matrix adjust. Identities = 137/233 (58%), Positives = 181/233 (77%), Gaps = 3/233 (1%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDER-TVRK 61 YDRA+++FSPDGH+FQVEYA EAVK+G+ AVGV+GK+ VVLG E++S KLQD R T K Sbjct: 4 YDRALSIFSPDGHIFQVEYALEAVKRGTCAVGVKGKNCVVLGCERRSTLKLQDTRITPSK 63 Query: 62 ICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQS 121 + +D +V ++F+GL AD+RI+I +ARVE QSHRLT+EDPVTVEY+TRY+A ++QRYTQS Sbjct: 64 VSKIDSHVVLSFSGLNADSRILIEKARVEAQSHRLTLEDPVTVEYLTRYVAGVQQRYTQS 123 Query: 122 NGRRPFGISALIVGFD-FDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYT-DD 179 G RPFG+S LI GFD D P+LYQT+PSG Y +W A IGR +K+VREFLEKNY + Sbjct: 124 GGVRPFGVSTLIAGFDPRDDEPKLYQTEPSGIYSSWSAQTIGRNSKTVREFLEKNYDRKE 183 Query: 180 AIETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQPLKILNPEEIEKYVAEI 232 T + +KL +++LLEVVQ+G KNIE+ V++ D + L+ EEI +YV +I Sbjct: 184 PPATVEECVKLTVRSLLEVVQTGAKNIEITVVKPDSDIVALSSEEINQYVTQI 236 >5FMG-D nrPDB Length = 241 Score = 250 bits (638), Expect = 5e-67, Method: Compositional matrix adjust. Identities = 118/244 (48%), Positives = 173/244 (70%), Gaps = 3/244 (1%) Query: 1 MSYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVR 60 MSYDRAITVFSPDGHL QVE+A EAVKKG AV ++ + VL VEKK++ KLQ+ +T Sbjct: 1 MSYDRAITVFSPDGHLLQVEHALEAVKKGGCAVAIKSSNFAVLAVEKKNIPKLQNPKTTE 60 Query: 61 KICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQ 120 K+ LD++ C+AFAGL ADAR+++N+ R+ECQ + L +++P V+YI +Y+A ++Q++T Sbjct: 61 KLIKLDEHNCLAFAGLNADARVLVNKTRLECQRYYLNMDEPAPVDYIAKYVAKVQQKFTH 120 Query: 121 SNGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDA 180 G RPFGI+ LI GF + +YQT+PSG Y AWKA AIG+ AK V+EFLEKNY ++ Sbjct: 121 RGGVRPFGIATLIAGFKNNKEICIYQTEPSGIYAAWKAQAIGKNAKIVQEFLEKNYQENM 180 Query: 181 IETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQPLKILNPEEIEKYVAEIEKEKEENE 240 + D I L +KA+ EVV+ KN+E+A++ ++ L + +EI V I++E+ +N Sbjct: 181 EQKD--CIFLALKAIFEVVELSSKNVEVALL-TEKDLTFIEEQEINSMVELIDQERTKNN 237 Query: 241 KKKQ 244 ++ + Sbjct: 238 EQNE 241 >6HE5-A nrPDB Length = 247 Score = 213 bits (543), Expect = 5e-56, Method: Compositional matrix adjust. Identities = 110/230 (47%), Positives = 157/230 (68%), Gaps = 3/230 (1%) Query: 1 MSYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVR 60 M YDRAITVFSPDG LFQVEYA+EAVK+G+TA+G++ K+ V+L +K+ +KL + T+ Sbjct: 7 MGYDRAITVFSPDGRLFQVEYAREAVKRGATAIGIKCKEGVILIADKRVGSKLLEADTIE 66 Query: 61 KICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQ 120 KI +D+++C A +GL ADAR++I+RAR+E Q +RLT ++P+TV+ + + I KQ+YTQ Sbjct: 67 KIYKIDEHICAATSGLVADARVLIDRARIEAQINRLTYDEPITVKELAKKICDFKQQYTQ 126 Query: 121 SNGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDA 180 G RPFG+S LI G D P+LY+TDPSG +KA AIG G +V EF EK Y DD Sbjct: 127 YGGVRPFGVSLLIAG--VDEVPKLYETDPSGALLEYKATAIGMGRNAVTEFFEKEYRDDL 184 Query: 181 IETDDLTIKLVIKALLEVVQSGGKNIELAVMR-RDQPLKILNPEEIEKYV 229 D + + LV L + +NIE+ ++ D+ K ++PEE++ YV Sbjct: 185 SFDDAMVLGLVAMGLSIESELVPENIEVGYVKVDDRTFKEVSPEELKPYV 234 >3H4P-A nrPDB Length = 264 Score = 189 bits (480), Expect = 9e-49, Method: Compositional matrix adjust. Identities = 98/194 (50%), Positives = 134/194 (69%), Gaps = 3/194 (1%) Query: 2 SYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRK 61 +YDRAITVFSP+G L+QVEYA+EAV++G+TA+G+ KD VVL V+++ +KL R++ K Sbjct: 11 AYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRSIEK 70 Query: 62 ICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQS 121 I +DD+V A +GL ADAR++I+RAR+E Q +RLT + +++E + + I +KQ YTQ Sbjct: 71 IFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQH 130 Query: 122 NGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAI 181 G RPFG+S LI G D RL++TDPSG +KA AIG G V E LEK Y DD Sbjct: 131 GGVRPFGVSLLIAGID-KNEARLFETDPSGALIEYKATAIGSGRPVVMELLEKEYRDDI- 188 Query: 182 ETDDLTIKLVIKAL 195 T D ++L I AL Sbjct: 189 -TLDEGLELAITAL 201 >2KU2-A nrPDB Length = 237 Score = 171 bits (433), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 96/231 (41%), Positives = 147/231 (63%), Gaps = 5/231 (2%) Query: 1 MSYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVR 60 M+ RAITVFSPDG LFQVEYA+EAVKKGSTA+G++ + V+L +KK ++L ++ ++ Sbjct: 10 MAGGRAITVFSPDGRLFQVEYAREAVKKGSTALGMKFANGVLLISDKKVRSRLIEQNSIE 69 Query: 61 KICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQ 120 KI +DD V +GL ADAR++++ AR+ Q ++T V +E + + +A Q+YTQ Sbjct: 70 KIQLIDDYVAAVTSGLVADARVLVDFARISAQQEKVTYGSLVNIENLVKRVADQMQQYTQ 129 Query: 121 SNGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDA 180 G RP+G+S + G D G PRL+ DP+GT + +KA AIG G +V FLE+ Y ++ Sbjct: 130 YGGVRPYGVSLIFAGIDQIG-PRLFDCDPAGTINEYKATAIGSGKDAVVSFLEREYKENL 188 Query: 181 IETDDLTIKLVIKALLEVVQSGG--KNIELAVMRRDQPLKILNPEEIEKYV 229 E + +T L IKAL ++ G K E+A + +I + EE++K++ Sbjct: 189 PEKEAVT--LGIKALKSSLEEGEELKAPEIASITVGNKYRIYDQEEVKKFL 237 >5LF0-A nrPDB Length = 234 Score = 169 bits (429), Expect = 7e-43, Method: Compositional matrix adjust. Identities = 90/235 (38%), Positives = 140/235 (59%), Gaps = 12/235 (5%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRKI 62 Y ++T FSP G L Q+EYA AV G+ +VG++ + VVL EKK + L DER+V K+ Sbjct: 6 YSFSLTTFSPSGKLVQIEYALAAVAGGAPSVGIKAANGVVLATEKKQKSILYDERSVHKV 65 Query: 63 CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122 + ++ + ++G+ D R++++RAR Q + L ++P+ + + +AS+ Q YTQS Sbjct: 66 EPITKHIGLVYSGMGPDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYTQSG 125 Query: 123 GRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYT----- 177 G RPFG+S LI G++ +G P L+Q+DPSG Y AWKA A+G+ + + FLEK Y Sbjct: 126 GVRPFGVSLLICGWN-EGRPYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNEDLEL 184 Query: 178 DDAIETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQPLKILNPEEIEKYVAEI 232 +DAI T LT+K + Q NIE+ + + + L P E++ Y+A I Sbjct: 185 EDAIHTAILTLKESFEG-----QMTEDNIEVGIC-NEAGFRRLTPTEVKDYLAAI 233 >5FMG-B nrPDB Length = 235 Score = 166 bits (421), Expect = 7e-42, Method: Compositional matrix adjust. Identities = 92/236 (38%), Positives = 136/236 (57%), Gaps = 11/236 (4%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRKI 62 Y ++T FSP G L Q+EYA V S A+G+R K+ V++ EKKS +L +E ++ KI Sbjct: 6 YSFSLTTFSPTGKLVQIEYALNRVSSSSPALGIRAKNGVIIATEKKSPNELIEENSIFKI 65 Query: 63 CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122 + +++ + +AG+ D R+++ RAR E + L + V+ + + IAS+ Q +TQ+ Sbjct: 66 QQISEHIGIVYAGMPGDFRVLLKRARKEAIRYSLQYGSEILVKELVKIIASIVQEFTQTG 125 Query: 123 GRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYT----- 177 G RPFG+S LI G D G LYQ DPSG Y W A +G+ ++ FLEK Y Sbjct: 126 GVRPFGLSLLICGVDVYGY-HLYQIDPSGCYFNWMATCVGKDYQNNMSFLEKRYNKDIEI 184 Query: 178 DDAIETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQPLKILNPEEIEKYVAEIE 233 +DAI T LT+K + +L KNIE+ V ++P KIL EI+ Y+ EIE Sbjct: 185 EDAIHTAILTLKESYEGVLN-----EKNIEIGVAYDNKPFKILTQNEIKDYLIEIE 235 >6J30-C nrPDB Length = 258 Score = 161 bits (407), Expect = 3e-40, Method: Compositional matrix adjust. Identities = 87/233 (37%), Positives = 135/233 (57%), Gaps = 11/233 (4%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERT-VRK 61 YD T+FSP+G L+QVEYA E++ TA+G+ D +VL E+K + L ++ T K Sbjct: 6 YDSRTTIFSPEGRLYQVEYALESISHAGTAIGIMASDGIVLAAERKVTSTLLEQDTSTEK 65 Query: 62 ICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQS 121 + L+D + +A AGLTADA I+IN AR+ Q++ T + + VE + R ++ +KQ YTQ Sbjct: 66 LYKLNDKIAVAVAGLTADAEILINTARIHAQNYLKTYNEDIPVEILVRRLSDIKQGYTQH 125 Query: 122 NGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAI 181 G RPFG+S + G+D +LY ++PSG Y WKA ++G + + L+ +Y DD + Sbjct: 126 GGLRPFGVSFIYAGYDDRYGYQLYTSNPSGNYTGWKAISVGANTSAAQTLLQMDYKDD-M 184 Query: 182 ETDDLTIKLVIKALLEVVQSGG---KNIELAVMRRDQP-----LKILNPEEIE 226 + DD I+L +K L + S +E A +R+ KI P+EI+ Sbjct: 185 KVDD-AIELALKTLSKTTDSSALTYDRLEFATIRKGANDGEVYQKIFKPQEIK 236 >5GJR-F nrPDB Length = 241 Score = 157 bits (398), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 86/241 (35%), Positives = 141/241 (58%), Gaps = 18/241 (7%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRKI 62 YDR + FSP+G LFQVEYA EA+K GSTA+G++ + V L VEK+ + L + ++ KI Sbjct: 8 YDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLMEPSSIEKI 67 Query: 63 CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122 +D ++ A +GL ADA+ +I++ARVE Q+H T + +TVE +T+ +++L ++ + + Sbjct: 68 VEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLALQFGEED 127 Query: 123 G-----RRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYT 177 RPFG++ L G D G P+L+ DPSGT+ A AIG ++ + L++ Y Sbjct: 128 ADPGAMSRPFGVALLFGGVDEKG-PQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEVY- 185 Query: 178 DDAIETDDLTIKLVIKALLEVVQS------GGKNIELAVMRRDQPLKILNPEEIEKYVAE 231 +T+K IK+ L +++ NIELA ++ Q + EE+E+ + + Sbjct: 186 -----HKSMTLKEAIKSSLIILKQVMEEKLNATNIELATVQPGQNFHMFTKEELEEVIKD 240 Query: 232 I 232 I Sbjct: 241 I 241 >2Z5C-C nrPDB Length = 262 Score = 157 bits (397), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 89/251 (35%), Positives = 149/251 (59%), Gaps = 13/251 (5%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRKI 62 YDR ++ FSP+G LFQVEY+ EA+K GSTA+G+ K+ VVLGVEK++ + L + ++ KI Sbjct: 10 YDRGVSTFSPEGRLFQVEYSLEAIKLGSTAIGIATKEGVVLGVEKRATSPLLESDSIEKI 69 Query: 63 CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122 +D ++ A +GLTADAR +I AR +H L ++ + VE +T+ + L R+ + Sbjct: 70 VEIDRHIGCAMSGLTADARSMIEHARTAAVTHNLYYDEDINVESLTQSVCDLALRFGEGA 129 Query: 123 G------RRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVR-EFLEKN 175 RPFG++ LI G D D +L+ +PSGT++ + A AIG G++ + E L + Sbjct: 130 SGEERLMSRPFGVALLIAGHDADDGYQLFHAEPSGTFYRYNAKAIGSGSEGAQAELLNEW 189 Query: 176 YTDDAIETDDLTIKLVIKALLEVVQS--GGKNIELAVMRRDQPLKILNPEEIEKYVAEIE 233 ++ ++ +L LV+K L +V++ N +L+ + + KI + E+ + + E+ Sbjct: 190 HSSLTLKEAEL---LVLKILKQVMEEKLDENNAQLSCITKQDGFKIYDNEKTAELIKEL- 245 Query: 234 KEKEENEKKKQ 244 KEKE E ++ Sbjct: 246 KEKEAAESPEE 256 >1G0U-D nrPDB Length = 241 Score = 155 bits (393), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 89/241 (36%), Positives = 145/241 (60%), Gaps = 10/241 (4%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRKI 62 YDR ++ FSP+G LFQVEY+ EA+K GSTA+G+ K+ VVLGVEK++ + L + ++ KI Sbjct: 8 YDRGVSTFSPEGRLFQVEYSLEAIKLGSTAIGIATKEGVVLGVEKRATSPLLESDSIEKI 67 Query: 63 CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122 +D ++ A +GLTADAR +I AR +H L ++ + VE +T+ + L S Sbjct: 68 VEIDRHIGCAMSGLTADARSMIEHARTAAVTHNLYYDEDINVESLTQSVCDLAAAAAMS- 126 Query: 123 GRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVR-EFLEKNYTDDAI 181 RPFG++ LI G D D +L+ +PSGT++ + A AIG G++ + E L + ++ + Sbjct: 127 --RPFGVALLIAGHDADDGYQLFHAEPSGTFYRYNAKAIGSGSEGAQAELLNEWHSSLTL 184 Query: 182 ETDDLTIKLVIKALLEVVQS--GGKNIELAVMRRDQPLKILNPEEIEKYVAEIEKEKEEN 239 + +L LV+K L +V++ N +L+ + + KI + E+ + + E+ KEKE Sbjct: 185 KEAEL---LVLKILKQVMEEKLDENNAQLSCITKQDGFKIYDNEKTAELIKEL-KEKEAA 240 Query: 240 E 240 E Sbjct: 241 E 241 >5LE5-B nrPDB Length = 261 Score = 154 bits (390), Expect = 3e-38, Method: Compositional matrix adjust. Identities = 80/234 (34%), Positives = 137/234 (58%), Gaps = 8/234 (3%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTV-RK 61 YD T+FSP+G L+QVEYA EA+ T +G+ D V+L E++++ KL DE K Sbjct: 5 YDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEK 64 Query: 62 ICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQS 121 I L++++ + AG+T+DA ++ N R+ Q + L ++P+ E + + +KQ YTQ Sbjct: 65 IYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQF 124 Query: 122 NGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAI 181 G+RPFG+S L +G+D +LYQ+DPSG Y WKA IG + + L+++Y + + Sbjct: 125 GGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEM 184 Query: 182 ETDDLTIKLVIKAL---LEVVQSGGKNIELAVMRRDQP---LKILNPEEIEKYV 229 T + L IK L ++V + + +E+A + R+ +++L +E+E+ + Sbjct: 185 -TLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLI 237 >4FZC-A nrPDB Length = 250 Score = 147 bits (370), Expect = 5e-36, Method: Compositional matrix adjust. Identities = 83/219 (37%), Positives = 130/219 (59%), Gaps = 9/219 (4%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRKI 62 Y ++T FSP G L Q++YA AVK+G T++G++ + VV+ EKKS + L T+ K+ Sbjct: 5 YSFSLTTFSPSGKLGQIDYALTAVKQGVTSLGIKATNGVVIATEKKSSSPLAMSETLSKV 64 Query: 63 CALDDNVCMAFAGLTADARIVINRAR--VECQSHRLTVEDPVTVEYITRYIASLKQRYTQ 120 L ++ ++G+ D R++++++R R+ E P T + + +A + Q TQ Sbjct: 65 SLLTPDIGAVYSGMGPDYRVLVDKSRKVAHTSYKRIYGEYPPT-KLLVSEVAKIMQEATQ 123 Query: 121 SNGRRPFGISALIVGFD-FDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDD 179 S G RPFG+S LI G D F+G LYQ DPSG+Y WKA AIG+G+ + + FLEK + D+ Sbjct: 124 SGGVRPFGVSLLIAGHDEFNGF-SLYQVDPSGSYFPWKATAIGKGSVAAKTFLEKRWNDE 182 Query: 180 AIETDDLTIKLVIKALLEVVQS--GGKNIELAVMRRDQP 216 +E +D I + + L E V+ G IELA++ + P Sbjct: 183 -LELED-AIHIALLTLKESVEGEFNGDTIELAIIGDENP 219 >5T0I-L nrPDB Length = 268 Score = 142 bits (359), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 80/246 (32%), Positives = 139/246 (56%), Gaps = 7/246 (2%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRKI 62 YD +TV+SP G + Q+EYA EAVK+GS VG++ K VL K++ ++L + +KI Sbjct: 11 YDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQ--KKI 68 Query: 63 CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122 +D+++ ++ AGLTADAR++ N R EC R + P+ V + I S Q TQ Sbjct: 69 LHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRY 128 Query: 123 GRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIE 182 GRRP+G+ LI G+D D P ++QT PS Y +A +IG ++S R +LE++ ++ Sbjct: 129 GRRPYGVGLLIAGYD-DMGPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFMEC 187 Query: 183 TDDLTIKLVIKALLEVVQS----GGKNIELAVMRRDQPLKILNPEEIEKYVAEIEKEKEE 238 + +K ++AL E + + KN+ + ++ +D I + +++ ++ +E+ + Sbjct: 188 NLNELVKHGLRALRETLPAEQDLTTKNVSIGIVGKDLEFTIYDDDDVSPFLEGLEERPQR 247 Query: 239 NEKKKQ 244 + Q Sbjct: 248 KAQPAQ 253 >5FMG-C nrPDB Length = 246 Score = 138 bits (347), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 71/178 (39%), Positives = 101/178 (56%), Gaps = 1/178 (0%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDE-RTVRK 61 YD T FSP+G L+QVEYA EA+ S +G+ KD V+LG +K ++KL D+ K Sbjct: 5 YDSRTTTFSPEGRLYQVEYALEAINNASITIGLITKDGVILGADKVFISKLIDKANNYEK 64 Query: 62 ICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQS 121 I +D ++ AGL ADA I+IN++R+ Q + + V + I +KQ YTQ Sbjct: 65 IYKIDKHIFCGVAGLNADANILINQSRLYAQRYLYNYNEVQPVSQLVVQICDIKQSYTQY 124 Query: 122 NGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDD 179 G RP+G+S LI G+D +LY TDPSG Y W A AIG + L++ + +D Sbjct: 125 GGLRPYGVSFLIGGYDTKDGYQLYHTDPSGNYSGWFATAIGTNNLTASSVLKQEWKND 182 >1IRU-A nrPDB Length = 246 Score = 136 bits (343), Expect = 7e-33, Method: Compositional matrix adjust. Identities = 81/234 (34%), Positives = 127/234 (54%), Gaps = 4/234 (1%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGS-TAVGVRGKDIVVLGVEKKSVAKLQDERTVRK 61 +DR IT+FSP+G L+QVEYA +A+ +G T+V VRGKD V+ +KK KL D TV Sbjct: 9 FDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTH 68 Query: 62 ICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQS 121 + + +N+ G+TAD+R + RAR E + + + V+ + + IA + Q YTQ+ Sbjct: 69 LFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQN 128 Query: 122 NGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAI 181 RP G +++G D + P++Y+ DP+G Y +KA A G FLEK Sbjct: 129 AEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFD 188 Query: 182 ETDDLTIKLVIKALLEVVQSGGK--NIELAVMRRDQP-LKILNPEEIEKYVAEI 232 T + T++ I L V+ K IE+ V+ + P +IL EI+ ++ + Sbjct: 189 WTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLVAL 242 >5FMG-E nrPDB Length = 256 Score = 136 bits (342), Expect = 9e-33, Method: Compositional matrix adjust. Identities = 80/236 (33%), Positives = 133/236 (56%), Gaps = 11/236 (4%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRKI 62 YDR + FSP+G LFQVEYA A+K GSTAVG+ D V+L E++ + L ++ +V K+ Sbjct: 8 YDRGVNTFSPEGRLFQVEYALGAIKLGSTAVGICVNDGVILASERRISSTLIEKDSVEKL 67 Query: 63 CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122 ++DD++ A +GL ADAR +I+ ARVEC ++ + + ++ I+ L ++ + Sbjct: 68 LSIDDHIGCAMSGLMADARTLIDYARVECNHYKFIYNENINIKSCVELISELALDFSNLS 127 Query: 123 G-------RRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKN 175 RPFG++ LI G D +G P L+ T+PSGT + A +IG + L++N Sbjct: 128 DSKRKKIMSRPFGVALLIGGVDKNG-PCLWYTEPSGTNTRFSAASIGSAQEGAELLLQEN 186 Query: 176 YTDD-AIETDDLTIKLVIKALLEVVQSGGKNIEL-AVMRRDQPLKILNPEEIEKYV 229 Y D E ++ V++ ++E S N+E+ A+ + DQ N ++I + + Sbjct: 187 YKKDMTFEQAEILALTVLRQVMEDKLS-TSNVEICAIKKSDQTFYKYNTDDISRII 241 >5FMG-F nrPDB Length = 254 Score = 133 bits (334), Expect = 7e-32, Method: Compositional matrix adjust. Identities = 75/253 (29%), Positives = 149/253 (58%), Gaps = 12/253 (4%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRKI 62 YD ++SP+G L+QVEYA EA+K+G+ AV ++ KD VV+ KK ++KL + KI Sbjct: 6 YDTDNIIYSPEGRLYQVEYASEAIKQGTCAVAIKSKDYVVVSGLKKCISKLSFPQ--EKI 63 Query: 63 CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122 +DD + ++ +G+T+DA+++ + EC SH+ + + +E + R +A Q+ TQ + Sbjct: 64 FKIDDYIGISMSGITSDAKVLTKFMQNECLSHKFLYNENINIESLVRSVADKYQKNTQKS 123 Query: 123 GRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKN-YTDDAI 181 +R FG+ +I + P +++T P+G+Y + A + G + + + +LEKN + + Sbjct: 124 SKRAFGVGLMIAA--YHNEPCIFETRPNGSYFEYDALSFGARSHASKTYLEKNLHLFEEC 181 Query: 182 ETDDLTIKLVIKALLEVVQSGGK----NIELAVMRRDQPLKILNPEEIEKYVAEI--EKE 235 ++L + +KAL + S + N LAV+ ++ P + ++ ++E+Y++++ + E Sbjct: 182 SLEELILH-CLKALKCSLSSESELTISNTALAVVGKNHPWQEISSLQLEEYLSKVKMDAE 240 Query: 236 KEENEKKKQKKAS 248 +E+ E+ Q +A+ Sbjct: 241 QEQVEENVQNEAN 253 >6EPD-G nrPDB Length = 255 Score = 127 bits (319), Expect = 5e-30, Method: Compositional matrix adjust. Identities = 81/250 (32%), Positives = 137/250 (54%), Gaps = 18/250 (7%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRKI 62 YD + + FSPDG +FQVEYA +AV+ STA+G+R KD VV GVEK ++KL +E + +++ Sbjct: 8 YDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKRL 67 Query: 63 CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122 +D +V MA AGL ADAR + + AR E + R + ++++ +A YT + Sbjct: 68 FNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYS 127 Query: 123 GRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIE 182 RPFG S ++ + + +LY DPSG + + AIG+ ++ + +EK ++ Sbjct: 128 AVRPFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEK------LQ 181 Query: 183 TDDLTIKLVIKALLEVV-----QSGGKNIELAVMRRDQPLKILNP-------EEIEKYVA 230 ++T + V+K + +++ + K EL + + K + EE EKY Sbjct: 182 MKEMTCRDVVKEVAKIIYIVHDEVKDKAFELELSWVGELTKGRHEIVPKDVREEAEKYAK 241 Query: 231 EIEKEKEENE 240 E KE++E++ Sbjct: 242 ESLKEEDESD 251 >3NZW-E nrPDB Length = 234 Score = 123 bits (308), Expect = 9e-29, Method: Compositional matrix adjust. Identities = 77/234 (32%), Positives = 122/234 (52%), Gaps = 10/234 (4%) Query: 2 SYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRK 61 +YD FSP G LFQVEYA EA+K+GS VG+R VL K++ +L + +K Sbjct: 5 NYDGDTVTFSPTGRLFQVEYALEAIKQGSVTVGLRSNTHAVLVALKRNADELSSYQ--KK 62 Query: 62 ICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQS 121 I D+++ ++ AGL DAR++ N R +C L + VE + Q+ TQS Sbjct: 63 IIKCDEHMGLSLAGLAPDARVLSNYLRQQCNYSSLVFNRKLAVERAGHLLCDKAQKNTQS 122 Query: 122 NGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAI 181 G RP+G+ LI+G+D G L + PSG AIG ++ + +LE+ D I Sbjct: 123 YGGRPYGVGLLIIGYDKSGA-HLLEFQPSGNVTELYGTAIGARSQGAKTYLERT-LDTFI 180 Query: 182 ETD---DLTIKLVIKALLEVVQSGG---KNIELAVMRRDQPLKILNPEEIEKYV 229 + D D IK ++A+ + ++ N+ +A++ +D P I + E + KY+ Sbjct: 181 KIDGNPDELIKAGVEAISQSLRDESLTVDNLSIAIVGKDTPFTIYDGEAVAKYI 234 >5FGG-F nrPDB Length = 288 Score = 121 bits (304), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 65/172 (37%), Positives = 98/172 (56%), Gaps = 1/172 (0%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRKI 62 YD + +VFSPDG FQVEYA +AV+ G+T++G++ D VV VEK +KL + KI Sbjct: 8 YDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVKI 67 Query: 63 CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122 +D ++ ++GL D R ++NR R E S + + P+ + + Q +T N Sbjct: 68 QVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYN 127 Query: 123 GRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEK 174 RPFG+S + G D +G LY +PSG+Y +K A G+G +S + LEK Sbjct: 128 SVRPFGVSTIFGGVDKNGA-HLYMLEPSGSYWGYKGAATGKGRQSAKAELEK 178 >6FVW-g nrPDB Length = 245 Score = 121 bits (304), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 65/173 (37%), Positives = 98/173 (56%), Gaps = 1/173 (0%) Query: 2 SYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRK 61 YD + +VFSPDG FQVEYA +AV+ G+T++G++ D VV VEK +KL + K Sbjct: 4 GYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVK 63 Query: 62 ICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQS 121 I +D ++ ++GL D R ++NR R E S + + P+ + + Q +T Sbjct: 64 IQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLY 123 Query: 122 NGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEK 174 N RPFG+S + G D +G LY +PSG+Y +K A G+G +S + LEK Sbjct: 124 NSVRPFGVSTIFGGVDKNGA-HLYMLEPSGSYWGYKGAATGKGRQSAKAELEK 175 >5L5W-G nrPDB Length = 252 Score = 102 bits (255), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 74/241 (30%), Positives = 122/241 (50%), Gaps = 9/241 (3%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGS-TAVGVRGKDIVVLGVEKKSVAKLQDERTVRK 61 YDR IT+FSP+G L+QVEYA +A + + ++ VRGKD V+ +KK KL D TV Sbjct: 12 YDRHITIFSPEGRLYQVEYAFKATNQTNINSLAVRGKDCTVVISQKKVPDKLLDPTTVSY 71 Query: 62 ICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQS 121 I + + M G DAR RA+ E R + + + + +A+L Q YTQ Sbjct: 72 IFCISRTIGMVVNGPIPDARNAALRAKAEAAEFRYKYGYDMPCDVLAKRMANLSQIYTQR 131 Query: 122 NGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAI 181 RP G+ V D + P +Y+TDP+G Y +KA A G + + LE ++ I Sbjct: 132 AYMRPLGVILTFVSVDEELGPSIYKTDPAGYYVGYKATATGPKQQEITTNLENHFKKSKI 191 Query: 182 -----ETDDLTIKLVIKALLEVV--QSGGKNIELAVMRRDQPLKILNPEEIEKYVAEIEK 234 E+ + ++ I +++ + + ++E+ V +D+ L+ E IE+ + I + Sbjct: 192 DHINEESWEKVVEFAITHMIDALGTEFSKNDLEVGVATKDK-FFTLSAENIEERLVAIAE 250 Query: 235 E 235 + Sbjct: 251 Q 251 >5FMG-A nrPDB Length = 260 Score = 102 bits (253), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 80/248 (32%), Positives = 126/248 (50%), Gaps = 18/248 (7%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGS-TAVGVRGKDIVVLGVEKK------SVAKLQD 55 YDR +T+FSPDG+L+Q+EYA +AVK + T+VGV+G++ V+ +KK S KL D Sbjct: 9 YDRHLTIFSPDGNLYQIEYAIKAVKNTNITSVGVKGENCAVIISQKKMATQYISQDKLLD 68 Query: 56 ERTVRKICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLK 115 + I + D + + G+ D ++ +AR E + V E + R I Sbjct: 69 YNNITNIYNITDEIGCSMVGMPGDCLSMVYKARSEASEFLYSNGYNVNAETLCRNICDKI 128 Query: 116 QRYTQSNGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAK---SVRE-F 171 Q YTQ R S +I+G D + P L++ DPSG ++A IG + SV E Sbjct: 129 QVYTQHAYMRLHACSGMIIGIDENNKPELFKFDPSGFCAGYRACVIGNKEQESISVLERL 188 Query: 172 LEKNYTDDAIETDDLTIK----LVIKALLEVVQSGGK--NIELAVMR-RDQPLKILNPEE 224 LEK ET D I+ L I+AL ++ K IE+A++ +++ ++ +E Sbjct: 189 LEKRKKKIQQETIDEDIRNTTILAIEALQTILAFDLKASEIEVAIVSTKNRNFTQISEKE 248 Query: 225 IEKYVAEI 232 I+ Y+ I Sbjct: 249 IDNYLTYI 256 >5FMG-G nrPDB Length = 252 Score = 89.0 bits (219), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 50/187 (26%), Positives = 95/187 (50%), Gaps = 7/187 (3%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSV--AKLQDERTVR 60 YD +++ FSPDG L+QVEY +++ +TA+ + KD ++ ++ K+ + + Sbjct: 8 YDLSVSTFSPDGRLYQVEYIYKSINNNNTALCLECKDGIICCCINSNMDKNKMIKKNSYN 67 Query: 61 KICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQ 120 +I +++N+ + ++G DAR +I+RAR E ++ + + + I+ YT Sbjct: 68 RIYHVNNNIIITYSGFDGDARNIIDRARSEANTYYYNFHTNIPLHILVNRISLYIHAYTL 127 Query: 121 SNGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLE-KNYTD- 178 RPF S +I F+ +Y +P+G + + IG+ + + +E K+Y D Sbjct: 128 YWHMRPFAASIIISSFNEKDKGDIYCIEPNGACYKYSGIVIGKNKEMFKTEIEKKDYKDI 187 Query: 179 ---DAIE 182 DAIE Sbjct: 188 NVRDAIE 194 >3H4P-a nrPDB Length = 219 Score = 62.0 bits (149), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 54/203 (26%), Positives = 92/203 (45%), Gaps = 8/203 (3%) Query: 30 STAVGVRGKDIVVLGVEKK-SVAKLQDERTVRKICALDDNVCMAFAGLTADARIVINRAR 88 +T VG+ D V+L +K+ S+ L ++ +K+ +DD + M AG DA+ ++ Sbjct: 2 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 61 Query: 89 VECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQTD 148 E + +++ + A+L S+ PF +I G+D +L+ D Sbjct: 62 AEAKLYKMRTGRNIP----PLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLD 117 Query: 149 PSGTYHAWKA-NAIGRGAKSVREFLEKNYTDDAIETDDLTIKL-VIKALLEVVQSGGKNI 206 P G + K A G G+ LE Y D + + + L +K+ +E G I Sbjct: 118 PLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGI 177 Query: 207 ELAVMRRDQPLKILNPEEIEKYV 229 LAV+ +D +KI EEIEK + Sbjct: 178 SLAVITKDG-VKIFEDEEIEKIL 199 >6HEC-1 nrPDB Length = 202 Score = 57.8 bits (138), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 55/210 (26%), Positives = 99/210 (47%), Gaps = 13/210 (6%) Query: 30 STAVGVRGKDIVVLGVEKK-SVAKLQDERTVRKICALDDNVCMAFAGLTADARIVINRAR 88 +T VG+ KD VV+ EK+ ++ + +KI + D + M AG DA+ + + Sbjct: 1 TTTVGLVCKDGVVMATEKRATMGNFIASKAAKKIYQIADRMAMTTAGSVGDAQFLARIIK 60 Query: 89 VECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQTD 148 +E + + E TV R IA+L S P+ + LI G D +G +Y D Sbjct: 61 IEANLYEIRRERKPTV----RAIATLTSNLLNSYRYFPYLVQLLIGGIDSEG-KSIYSID 115 Query: 149 P-SGTYHAWKANAIGRGAKSVREFLEKNYTDDAIETDDLTIKLVIKALLEVVQ---SGGK 204 P G A G G+ + LE +T + I D+ ++L ++A+ ++ + G Sbjct: 116 PIGGAIEEKDIVATGSGSLTAYGVLEDRFTPE-IGVDE-AVELAVRAIYSAMKRDSASGD 173 Query: 205 NIELAVMRRDQPLKILNPEEIEKYVAEIEK 234 I++ + D+ + +PEE+E+ +A+ K Sbjct: 174 GIDVVKITEDEFYQ-YSPEEVEQILAKFRK 202 >3IPM-H nrPDB Length = 217 Score = 56.6 bits (135), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 50/208 (24%), Positives = 95/208 (45%), Gaps = 12/208 (5%) Query: 24 EAVKKGSTAVGVRGKDIVVLGVEKK-SVAKLQDERTVRKICALDDNVCMAFAGLTADARI 82 + ++ G+T VG+ KD V++ E++ ++ + +K+ +D M AGL DA++ Sbjct: 3 QTLETGTTTVGITLKDAVIMATERRVTMENFIMHKNGKKLFQIDTYTGMTIAGLVGDAQV 62 Query: 83 VINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTP 142 ++ + E + +RL + +E +A+L P+ + L+ G D P Sbjct: 63 LVRYMKAELELYRLQRRVNMPIE----AVATLLSNMLNQVKYMPYMVQLLVGGIDT--AP 116 Query: 143 RLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIETDDLTIKLVIKALLEVVQ-- 200 ++ D +G + G G+ V LE Y++ T D + LVI+A+ Q Sbjct: 117 HVFSIDAAGGSVEDIYASTGSGSPFVYGVLESQYSEKM--TVDEGVDLVIRAISAAKQRD 174 Query: 201 -SGGKNIELAVMRRDQPLKILNPEEIEK 227 + G I++AV+ R L ++IE Sbjct: 175 SASGGMIDVAVITRKDGYVQLPTDQIES 202 >3NZW-L nrPDB Length = 241 Score = 55.5 bits (132), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 38/151 (25%), Positives = 66/151 (43%), Gaps = 10/151 (6%) Query: 28 KGSTAVGVRGKDIVVLGVEKKSVAKLQ-DERTVRKICALDDNVCMAFAGLTADARIVINR 86 G T +G+ G+D VL + +++ + R K+ DN+ M+ G AD ++ R Sbjct: 27 NGGTILGIAGEDFAVLAGDTRNITDYSINSRYEPKVFDCGDNIVMSANGFAADGDALVKR 86 Query: 87 ARVECQSHRLTVEDP-VTVEYITRYIASLKQRYTQSNGRR--PFGISALIVGFDFDGTPR 143 + + + D +++ R I L G+R P+ + +I G D DG Sbjct: 87 FKNSVKWYHFDHNDKKLSINSAARNIQHLLY------GKRFFPYYVHTIIAGLDEDGKGA 140 Query: 144 LYQTDPSGTYHAWKANAIGRGAKSVREFLEK 174 +Y DP G+Y + A G A + FL+ Sbjct: 141 VYSFDPVGSYEREQCRAGGAAASLIMPFLDN 171 >3UNH-H nrPDB Length = 234 Score = 51.2 bits (121), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 47/187 (25%), Positives = 87/187 (46%), Gaps = 14/187 (7%) Query: 30 STAVGVRGKDIVVLGVEKKSVA-KLQDERTVRKICALDDNVCMAFAGLTADARIVINRAR 88 +T G+ +D V+LG + ++ + +++ KI + + AG+ AD + A Sbjct: 1 TTIAGLVFRDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADTEMTTRMAA 60 Query: 89 VECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQTD 148 + + H L+ V +TR L+Q + G G S ++ G D +G P+LY+ Sbjct: 61 SKMELHALSTGREPRVATVTRI---LRQTLFRYQGH--VGASLVVGGVDLNG-PQLYEVH 114 Query: 149 PSGTYHAWKANAIGRGAKSVREFLE----KNYTDDAIETDDLTIKLVIKALLEVVQSGGK 204 P G+Y A+G G + LE N T +A + +L ++ + +L + SGG Sbjct: 115 PHGSYSRLPFTALGSGQGAAVALLEDRFQPNMTLEAAQ--ELLVEAITAGILSDLGSGG- 171 Query: 205 NIELAVM 211 N++ V+ Sbjct: 172 NVDACVI 178 >5FMG-I nrPDB Length = 229 Score = 50.8 bits (120), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 42/190 (22%), Positives = 86/190 (45%), Gaps = 12/190 (6%) Query: 30 STAVGVRGKDIVVLGVEKKSV-AKLQDERTVRKICALDDNVCMAFAGLTADARIVINRAR 88 +T G+ ++ V+LG + ++ + ++ K+ + N+ A AG+ D + Sbjct: 1 TTICGLVCQNAVILGADTRATEGPIVADKNCSKLHYISKNIWCAGAGVAGDLEHTTLWLQ 60 Query: 89 VECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVG-FDFDGTPRLYQT 147 + HRL T ++ ++ L Q + G + + A+++G D +G P+LY Sbjct: 61 HNVELHRLNTN---TQPRVSMCVSRLTQELFKYQGYK---VCAIVLGGVDVNG-PQLYGI 113 Query: 148 DPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAI--ETDDLTIKLVIKALLEVVQSGGKN 205 P G+ A+G G+ + LE Y D+ E +L + + + + SGG N Sbjct: 114 HPHGSSCLLPFTALGSGSLNAMAVLEAKYRDNMTIEEGKNLVCEAICAGIFNDLGSGG-N 172 Query: 206 IELAVMRRDQ 215 +++ V+ +D Sbjct: 173 VDICVITKDS 182 >6AVO-B nrPDB Length = 234 Score = 47.8 bits (112), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 48/189 (25%), Positives = 85/189 (44%), Gaps = 14/189 (7%) Query: 30 STAVGVRGKDIVVLGVEKKSVA-KLQDERTVRKICALDDNVCMAFAGLTADARIVINRAR 88 +T G+ +D V+LG + ++ + +++ KI + + AG+ ADA + Sbjct: 1 TTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADAEMTTRMVA 60 Query: 89 VECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQTD 148 + + H L+ V +TR L+Q + G G S ++ G D G P+LY Sbjct: 61 SKMELHALSTGREPRVATVTRI---LRQTLFRYQGH--VGASLIVGGVDLTG-PQLYGVH 114 Query: 149 PSGTYHAWKANAIGRGAKSVREFLE----KNYTDDAIETDDLTIKLVIKALLEVVQSGGK 204 P G+Y A+G G + LE N T +A + L ++ V +L + SGG Sbjct: 115 PHGSYSRLPFTALGSGQDAALAVLEDRFQPNMTLEAAQ--GLLVEAVTAGILGDLGSGG- 171 Query: 205 NIELAVMRR 213 N++ V+ + Sbjct: 172 NVDACVITK 180 >6EPF-2 nrPDB Length = 277 Score = 46.6 bits (109), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 51/206 (24%), Positives = 84/206 (40%), Gaps = 13/206 (6%) Query: 24 EAVKKGSTAVGVRGKDIVVLGVEKKSV-AKLQDERTVRKICALDDNVCMAFAGLTADARI 82 +A K G+T GV KD +VLG + ++ + ++ KI + N+ AG AD + Sbjct: 38 KARKTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDM 97 Query: 83 VINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTP 142 + H LT V R + + RY + G + ++ G D G P Sbjct: 98 TTQLISSNLELHSLTTGRLPRVVTANRMLKQMLFRY-----QGYIGAALVLGGVDVTG-P 151 Query: 143 RLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIETDDLTIKLVIKALLEVV--- 199 LY P G+ +G G+ + E + D E + KLV +A+ + Sbjct: 152 HLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEE--AKKLVSEAIAAGIFND 209 Query: 200 QSGGKNIELAVMRRDQPLKILNPEEI 225 G NI+L V+ + + L L P + Sbjct: 210 LGSGSNIDLCVISKSK-LDFLRPYSV 234 >5L4G-8 nrPDB Length = 277 Score = 45.4 bits (106), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 47/202 (23%), Positives = 83/202 (41%), Gaps = 11/202 (5%) Query: 27 KKGSTAVGVRGKDIVVLGVEKKSV-AKLQDERTVRKICALDDNVCMAFAGLTADARIVIN 85 K G+T GV KD +VLG + ++ + ++ KI + N+ AG AD + Sbjct: 41 KTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQ 100 Query: 86 RARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLY 145 + H L+ V R + + RY + G + ++ G D G P LY Sbjct: 101 LISSNLELHSLSTGRLPRVVTANRMLKQMLFRY-----QGYIGAALVLGGVDVTG-PHLY 154 Query: 146 QTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIETD--DLTIKLVIKALLEVVQSGG 203 P G+ +G G+ + E + D E + +L + + + + S G Sbjct: 155 SIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGS-G 213 Query: 204 KNIELAVMRRDQPLKILNPEEI 225 NI+L V+ +++ L L P + Sbjct: 214 SNIDLCVISKNK-LDFLRPYTV 234 >3NZW-K nrPDB Length = 287 Score = 43.1 bits (100), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 37/182 (20%), Positives = 77/182 (42%), Gaps = 7/182 (3%) Query: 26 VKKGSTAVGVRGKDIVVLGVEKKSVA-KLQDERTVRKICALDDNVCMAFAGLTADARIVI 84 + G+T + R + +++ V+ ++ A +TV+K+ ++ + AG AD + Sbjct: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 Query: 85 NRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRL 144 +C+ H L ++ ++V ++ +++L +Y + + +I G+ P + Sbjct: 132 TWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAG----LSMGTMICGYTRKEGPTI 187 Query: 145 YQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIETDDLTI--KLVIKALLEVVQSG 202 Y D GT +G G L+ NY D D L + + ++ A SG Sbjct: 188 YYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSG 247 Query: 203 GK 204 G Sbjct: 248 GS 249 >5FMG-K nrPDB Length = 195 Score = 42.4 bits (98), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 49/189 (25%), Positives = 78/189 (41%), Gaps = 16/189 (8%) Query: 31 TAVGVRGKDIVVLGVEK---KSVAKLQDERTVRKICALDDNVCMAFAGLTADARIVIN-- 85 T +G+RG + VVL + S+ KL+++ K + N C+ G D R+ Sbjct: 3 TLIGLRGNNFVVLAADTYSINSIIKLKNDDNT-KFYDIHGNKCLLLGGSIGD-RLQFGEF 60 Query: 86 -RARVECQSHRLTVEDPV-TVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPR 143 R V ++ + V + + TR + R R PF ++ LI G+D + Sbjct: 61 IRKNVHLYQYQNNTDMFVKSFAFFTRKNLAYYLR------RNPFEVNCLIAGYDKKDGYQ 114 Query: 144 LYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIETDDLTI-KLVIKALLEVVQSG 202 LY D + A G GA V L+K Y ++ + L I KL + L + Sbjct: 115 LYWCDYLSNMDSVNKGAHGYGAYLVSAILDKYYHENLTVDEALDIFKLCFEELKKRFLLT 174 Query: 203 GKNIELAVM 211 N EL +M Sbjct: 175 QINYELRIM 183 >5FGE-J nrPDB Length = 198 Score = 42.4 bits (98), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 43/171 (25%), Positives = 75/171 (43%), Gaps = 15/171 (8%) Query: 33 VGVRGKDIVVLGVEKK-----SVAKLQDERTVRKICALDDNVCMAFAGLTADARIVINRA 87 +G+R +D V+L K SV K D++T + L + M+FAG D Sbjct: 5 LGIRVQDSVILASSKAVTRGISVLKDSDDKTRQ----LSPHTLMSFAGEAGDTVQFAEYI 60 Query: 88 RVECQSHRLTVEDPVTVEYITRYIASLKQRYTQS-NGRRPFGISALIVGFD-FDGTPRLY 145 + Q + + + ++ + ++ ++ +Q +S RRP+ ++ LI G+D P LY Sbjct: 61 QANIQLYSIREDYELSPQAVSSFV---RQELAKSIRSRRPYQVNVLIGGYDKKKNKPELY 117 Query: 146 QTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIETDDL-TIKLVIKAL 195 Q D GT A G L+ +Y D + L +KL ++ L Sbjct: 118 QIDYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQEL 168 >3WXR-K nrPDB Length = 238 Score = 42.0 bits (97), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 43/171 (25%), Positives = 75/171 (43%), Gaps = 15/171 (8%) Query: 33 VGVRGKDIVVLGVEKK-----SVAKLQDERTVRKICALDDNVCMAFAGLTADARIVINRA 87 +G+R +D V+L K SV K D++T + L + M+FAG D Sbjct: 5 LGIRVQDSVILASSKAVTRGISVLKDSDDKTRQ----LSPHTLMSFAGEAGDTVQFAEYI 60 Query: 88 RVECQSHRLTVEDPVTVEYITRYIASLKQRYTQS-NGRRPFGISALIVGFD-FDGTPRLY 145 + Q + + + ++ + ++ ++ +Q +S RRP+ ++ LI G+D P LY Sbjct: 61 QANIQLYSIREDYELSPQAVSSFV---RQELAKSIRSRRPYQVNVLIGGYDKKKNKPELY 117 Query: 146 QTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIETDDL-TIKLVIKAL 195 Q D GT A G L+ +Y D + L +KL ++ L Sbjct: 118 QIDYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQEL 168 >6EPF-5 nrPDB Length = 263 Score = 40.4 bits (93), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 40/195 (20%), Positives = 87/195 (44%), Gaps = 9/195 (4%) Query: 28 KGSTAVGVRGKDIVVLGVEKKSVA-KLQDERTVRKICALDDNVCMAFAGLTADARIVINR 86 G+T + + + V++ + ++ A +TV+K+ ++ + AG AD Sbjct: 58 HGTTTLAFKFQHGVIVAADSRATAGPYIASQTVKKVIEINPYLLGTMAGGAADCSFWERL 117 Query: 87 ARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQ 146 +C+ + L ++ ++V ++ +A++ +Y + +I G+D G P LY Sbjct: 118 LARQCRIYELRNKERISVAAASKLLANMVYQYKGMG----LSMGTMICGWDKRG-PGLYY 172 Query: 147 TDPSGTYHAWKANAIGRGAKSVREFLEKNYTDD--AIETDDLTIKLVIKALLEVVQSGGK 204 D G + A ++G G+ +++ Y+ D E DL + + +A SGG Sbjct: 173 VDSEGNRISGTAFSVGSGSVYAFGVMDRGYSYDLQVEEAYDLARRAIYQATYRDAYSGGA 232 Query: 205 NIELAVMRRDQPLKI 219 + L +R D +++ Sbjct: 233 -VNLYHVREDGWIRV 246 >3UNB-K nrPDB Length = 205 Score = 39.7 bits (91), Expect = 0.001, Method: Compositional matrix adjust. Identities = 39/184 (21%), Positives = 82/184 (44%), Gaps = 12/184 (6%) Query: 40 IVVLGVEKKSVAKLQDERTVRKICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVE 99 ++V + + +TV+K+ ++ + AG AD +C+ + L + Sbjct: 12 VIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLARQCRIYELRNK 71 Query: 100 DPVTVEYITRYIASLKQRYTQSNGRRPFGIS--ALIVGFDFDGTPRLYQTDPSGTYHAWK 157 + ++V ++ +A++ +Y + G+S +I G+D G P LY D G + Sbjct: 72 ERISVAAASKLLANMVYQY------KGMGLSMGTMICGWDKRG-PGLYYVDSEGNRISGT 124 Query: 158 ANAIGRGAKSVREFLEKNYTDD--AIETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQ 215 A ++G G+ +++ Y+ D E DL + + +A SGG + L +R D Sbjct: 125 AFSVGSGSVYAYGVMDRGYSYDLKVEEAYDLARRAIYQATYRDAYSGGA-VNLYHVREDG 183 Query: 216 PLKI 219 +++ Sbjct: 184 WIRV 187 >5CZ8-K nrPDB Length = 221 Score = 39.7 bits (91), Expect = 0.001, Method: Compositional matrix adjust. Identities = 43/218 (19%), Positives = 90/218 (41%), Gaps = 8/218 (3%) Query: 26 VKKGSTAVGVRGKDIVVLGVEKKSVA-KLQDERTVRKICALDDNVCMAFAGLTADARIVI 84 + G+T + R + +++ V+ ++ A +TV+ + ++ + AG AD + Sbjct: 6 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKAVIEINPFLLGTMAGGAADCQFWE 65 Query: 85 NRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRL 144 +C+ H L ++ ++V ++ +++L +Y + + +I G+ P + Sbjct: 66 TWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAG----LSMGTMICGYTRKEGPTI 121 Query: 145 YQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIETDDLTI--KLVIKALLEVVQSG 202 Y D GT +G G L+ NY D D L + + ++ A SG Sbjct: 122 YYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSG 181 Query: 203 GKNIELAVMRRDQPLKILNPEEIEKYVAEIEKEKEENE 240 G ++ L + D + N + E + E+E N Sbjct: 182 G-SVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNN 218 >5FGI-H nrPDB Length = 244 Score = 39.7 bits (91), Expect = 0.001, Method: Compositional matrix adjust. Identities = 46/197 (23%), Positives = 81/197 (41%), Gaps = 22/197 (11%) Query: 24 EAVKKGSTAVGVRGKDIVVLGVEKKSV-AKLQDERTVRKICALDDNVCMAFAGLTADARI 82 +A G+T VGV+ + VV+ + +S + ++ K+ + + A AG AD Sbjct: 7 KATSTGATIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEA 66 Query: 83 VINRARVECQSHRL-TVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGT 141 V + H L T +P V + LKQ + G G ++ G D G+ Sbjct: 67 VTQLIGSNIELHSLYTSREPRVVSALQM----LKQHLFKYQGH--IGAYLIVAGVDPTGS 120 Query: 142 PRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIETDDLTIKLVIKALLEVVQS 201 L+ G+ ++G G+ + LE ++ DLT + IK + +Q+ Sbjct: 121 -HLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHW------KQDLTKEEAIKLASDAIQA 173 Query: 202 G-------GKNIELAVM 211 G G N+++ VM Sbjct: 174 GIWNDLGSGSNVDVCVM 190 >5FMG-M nrPDB Length = 240 Score = 39.7 bits (91), Expect = 0.001, Method: Compositional matrix adjust. Identities = 32/150 (21%), Positives = 63/150 (42%), Gaps = 5/150 (3%) Query: 26 VKKGSTAVGVRGKDIVVLGVEKK-SVAKLQDERTVRKICALDDNVCMAFAGLTADARIVI 84 + G T +G+ GKD V+L + + S++ R KI L D + +G+ +D + + Sbjct: 34 IDNGGTVIGLTGKDYVILAADTRLSLSYSIYTRFCPKISKLTDKCIIGSSGMQSDIKTLH 93 Query: 85 NRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRL 144 + + + Q L + I R + + S P+ ++ G D + L Sbjct: 94 SLLQKKIQLFVLEHSHYPDIHVIARLLCVI----LYSRRFFPYYAFNILAGVDENNKGVL 149 Query: 145 YQTDPSGTYHAWKANAIGRGAKSVREFLEK 174 Y D G+Y + +G G++ + L+ Sbjct: 150 YNYDSVGSYCEATHSCVGSGSQLILPILDN 179 >5LN3-5 nrPDB Length = 263 Score = 38.9 bits (89), Expect = 0.002, Method: Compositional matrix adjust. Identities = 39/196 (19%), Positives = 88/196 (44%), Gaps = 11/196 (5%) Query: 28 KGSTAVGVRGKDIVVLGVEKKSVAKLQ-DERTVRKICALDDNVCMAFAGLTADARIVINR 86 G+T + + + V++ + ++ A +TV+K+ ++ + AG AD Sbjct: 58 HGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERL 117 Query: 87 ARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQ 146 +C+ + L ++ ++V ++ +A++ +Y + +I G+D G P LY Sbjct: 118 LARQCRIYELRNKERISVAAASKLLANMVYQYKGMG----LSMGTMICGWDKRG-PGLYY 172 Query: 147 TDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIETD---DLTIKLVIKALLEVVQSGG 203 D G + ++G G+ +++ Y+ D +E + DL + + +A SGG Sbjct: 173 VDSEGNRISGATFSVGSGSVYAYGVMDRGYSYD-LEVEQAYDLARRAIYQATYRDAYSGG 231 Query: 204 KNIELAVMRRDQPLKI 219 + L +R D +++ Sbjct: 232 A-VNLYHVREDGWIRV 246 >5L64-K nrPDB Length = 211 Score = 35.4 bits (80), Expect = 0.026, Method: Compositional matrix adjust. Identities = 36/169 (21%), Positives = 72/169 (42%), Gaps = 11/169 (6%) Query: 40 IVVLGVEKKSVAKLQDERTVRKICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVE 99 ++V + + +TV+K+ ++ + AG AD +C+ + L + Sbjct: 12 VIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLARQCRIYELRNK 71 Query: 100 DPVTVEYITRYIASLKQRYTQSNGRRPFGIS--ALIVGFDFDGTPRLYQTDPSGTYHAWK 157 + ++V ++ +A++ +Y + G+S +I G+D G P LY D G + Sbjct: 72 ERISVAAASKLLANMVYQY------KGMGLSMGTMICGWDKRG-PGLYYVDSEGNRISGA 124 Query: 158 ANAIGRGAKSVREFLEKNYTDDAIETDDLTI--KLVIKALLEVVQSGGK 204 ++G G+ L+ NY D D L + + ++ A SGG Sbjct: 125 TFSVGSGSVYAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGS 173 >5L5A-K nrPDB Length = 211 Score = 34.7 bits (78), Expect = 0.044, Method: Compositional matrix adjust. Identities = 35/150 (23%), Positives = 64/150 (42%), Gaps = 11/150 (7%) Query: 59 VRKICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRY 118 V K+ ++ + +G AD + EC+ + L + ++V ++ ++++ +Y Sbjct: 31 VNKVIEINPYLLGTMSGCAADCQYWETLLAKECRLYYLRNGERISVSAASKLLSNMMCQY 90 Query: 119 TQSNGRRPFGIS--ALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNY 176 R G+S ++I G+D G P LY D GT + + G G L+ NY Sbjct: 91 ------RGMGLSMGSMICGWDKKG-PGLYYVDEHGTRLSGNMFSTGSGNTYAYGVLDSNY 143 Query: 177 TDDAIETDDLTI--KLVIKALLEVVQSGGK 204 D D L + + ++ A SGG Sbjct: 144 KWDLSVEDALYLGKRSILAAAHRDAYSGGS 173 >5FMG-N nrPDB Length = 265 Score = 33.9 bits (76), Expect = 0.062, Method: Compositional matrix adjust. Identities = 27/119 (22%), Positives = 57/119 (47%), Gaps = 12/119 (10%) Query: 26 VKKGSTAVGVRGKDIVVLGVEKK----SVAKLQDERTVRKICALDDNVCMAFAGLTADAR 81 V G++ + ++ K +++ ++K S AK Q+ V +I +++ M F+G ADA+ Sbjct: 6 VVTGTSVIAIKYKHGIMIAADRKASYGSYAKFQN---VERIFKINNKTVMGFSGELADAQ 62 Query: 82 I---VINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFD 137 ++ R + S + ED T ++ Y++ + Y + N P + +I G + Sbjct: 63 YLHELLTRKNINNLSEKKRKEDMYTPQHYHSYVSRV--FYVRKNRIDPLFNNIIIAGIN 119 >6AVO-A nrPDB Length = 199 Score = 31.2 bits (69), Expect = 0.40, Method: Compositional matrix adjust. Identities = 22/98 (22%), Positives = 44/98 (44%), Gaps = 6/98 (6%) Query: 41 VVLGVEKK-SVAKLQDERTVRKICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVE 99 VV+G + + S + R K+ L + + A +G ADA+ V + A + + H + +E Sbjct: 12 VVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAVADMAAYQLELHGIELE 71 Query: 100 DPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFD 137 +P V + ++ +Y R ++ G+D Sbjct: 72 EPPLVLAAANVVRNISYKY-----REDLSAHLMVAGWD 104 >3BB7-A nrPDB Length = 321 Score = 31.2 bits (69), Expect = 0.48, Method: Compositional matrix adjust. Identities = 15/53 (28%), Positives = 30/53 (56%), Gaps = 9/53 (16%) Query: 181 IETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQPLKILNPEEIEKYVAEIE 233 +ETD+ + K +KA+ EV+ + ++ ++PL ++ P+ KY AE+ Sbjct: 44 VETDNPSFKWWLKAIDEVITN--------AVKSNKPLNVIKPDP-SKYAAEVS 87 >5FMG-J nrPDB Length = 218 Score = 30.8 bits (68), Expect = 0.58, Method: Compositional matrix adjust. Identities = 22/111 (19%), Positives = 49/111 (44%), Gaps = 6/111 (5%) Query: 28 KGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVR--KICALDDNVCMAFAGLTADARIVIN 85 G +G+ G + V + + + A + + KI +++NV + +GL D + + Sbjct: 8 NGGCVLGMSGSNCVAIACDLRLGANTFTTVSTKFSKIFKMNNNVYVGLSGLATDIQTLYE 67 Query: 86 RARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGF 136 R + + + + VE ++S+ SN P+ ++ ++VGF Sbjct: 68 ILRYRVNLYEVRQDAEMDVECFANMLSSI----LYSNRFSPYFVNPIVVGF 114 >3C1M-A nrPDB Length = 473 Score = 30.4 bits (67), Expect = 0.72, Method: Compositional matrix adjust. Identities = 21/81 (25%), Positives = 35/81 (43%), Gaps = 1/81 (1%) Query: 74 AGLTADARIVINRA-RVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISAL 132 AG+ D R R+E + L + + +T +I + ++ Y + GR SA Sbjct: 156 AGIITDNNFGSARVKRLEVKERLLPLLKEGIIPVVTGFIGTTEEGYITTLGRGGSDYSAA 215 Query: 133 IVGFDFDGTPRLYQTDPSGTY 153 ++G+ D TD SG Y Sbjct: 216 LIGYGLDADIIEIWTDVSGVY 236 >5VFT-S nrPDB Length = 213 Score = 30.0 bits (66), Expect = 0.92, Method: Compositional matrix adjust. Identities = 29/150 (19%), Positives = 56/150 (37%), Gaps = 5/150 (3%) Query: 26 VKKGSTAVGVRGKDIVVLGVEKKSVAKLQ-DERTVRKICALDDNVCMAFAGLTADARIVI 84 V G T + + G+D ++ + + R K L D + +G D + Sbjct: 6 VFNGGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLT 65 Query: 85 NRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRL 144 + ++ + +T T IA++ S P+ + +I G D +G + Sbjct: 66 KIIEARLKMYKHSNNKAMT----TGAIAAMLSTILYSRRFFPYYVYNIIGGLDEEGKGAV 121 Query: 145 YQTDPSGTYHAWKANAIGRGAKSVREFLEK 174 Y DP G+Y A G + ++ L+ Sbjct: 122 YSFDPVGSYQRDSFKAGGSASAMLQPLLDN 151 >5L4G-U nrPDB Length = 241 Score = 29.6 bits (65), Expect = 1.1, Method: Compositional matrix adjust. Identities = 29/150 (19%), Positives = 56/150 (37%), Gaps = 5/150 (3%) Query: 26 VKKGSTAVGVRGKDIVVLGVEKKSVAKLQ-DERTVRKICALDDNVCMAFAGLTADARIVI 84 V G T + + G+D ++ + + R K L D + +G D + Sbjct: 34 VFNGGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLT 93 Query: 85 NRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRL 144 + ++ + +T T IA++ S P+ + +I G D +G + Sbjct: 94 KIIEARLKMYKHSNNKAMT----TGAIAAMLSTILYSRRFFPYYVYNIIGGLDEEGKGAV 149 Query: 145 YQTDPSGTYHAWKANAIGRGAKSVREFLEK 174 Y DP G+Y A G + ++ L+ Sbjct: 150 YSFDPVGSYQRDSFKAGGSASAMLQPLLDN 179 >6EPF-6 nrPDB Length = 240 Score = 29.6 bits (65), Expect = 1.3, Method: Compositional matrix adjust. Identities = 33/169 (19%), Positives = 63/169 (37%), Gaps = 8/169 (4%) Query: 9 VFSPDGHL--FQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQ-DERTVRKICAL 65 V P G Q+ ++ A G T + + G+D ++ + + R K L Sbjct: 15 VMGPQGSAGPVQMRFSPYAFN-GGTVLAIAGEDFSIVASDTRLSEGFSIHTRDSPKCYKL 73 Query: 66 DDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRR 125 D + +G D + + ++ + +T T IA++ S Sbjct: 74 TDKTVIGCSGFHGDCLTLTKIIEARLKMYKHSNNKAMT----TGAIAAMLSTILYSRRFF 129 Query: 126 PFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEK 174 P+ + +I G D +G +Y DP G+Y A G + ++ L+ Sbjct: 130 PYYVYNIIEGLDEEGKGAVYSFDPVGSYQRDSFKAGGSASAMLQPLLDN 178 >5MPC-h nrPDB Length = 215 Score = 29.3 bits (64), Expect = 1.8, Method: Compositional matrix adjust. Identities = 38/207 (18%), Positives = 83/207 (40%), Gaps = 13/207 (6%) Query: 26 VKKGSTAVGVRGKDIVVLGVEKKSV-AKLQDERTVRKICALDDNVCMAFAGLTADARIVI 84 V G++ + V KD V+LG + ++ R K+ + D + +G AD + + Sbjct: 16 VSLGTSIMAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDKIWCCRSGSAADTQAIA 75 Query: 85 NRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRL 144 + + + + P T AS+ + N + ++ G+D + Sbjct: 76 DIVQYHLELYTSQYGTPST-----ETAASVFKELCYEN-KDNLTAGIIVAGYDDKNKGEV 129 Query: 145 YQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIETDDLTIKLVIKALLEVVQ---S 201 Y G+ H G G+ + + +KN+ ++ + + T+ + +L + ++ S Sbjct: 130 YTIPLGGSVHKLPYAIAGSGSTFIYGYCDKNFRENM--SKEETVDFIKHSLSQAIKWDGS 187 Query: 202 GGKNIELAVMRRDQPLK-ILNPEEIEK 227 G I + V+ + I P+E E+ Sbjct: 188 SGGVIRMVVLTAAGVERLIFYPDEYEQ 214 >2FV8-A nrPDB Length = 207 Score = 28.9 bits (63), Expect = 1.9, Method: Compositional matrix adjust. Identities = 20/60 (33%), Positives = 33/60 (55%), Gaps = 2/60 (3%) Query: 183 TDDLTIKLVIKALLEVVQSG--GKNIELAVMRRDQPLKILNPEEIEKYVAEIEKEKEENE 240 T++L + +I+ L VV G GK L V +D+ ++ P E YVA+IE + ++ E Sbjct: 15 TENLYFQSMIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVE 74 >6DTT-A nrPDB Length = 383 Score = 28.5 bits (62), Expect = 2.5, Method: Compositional matrix adjust. Identities = 13/24 (54%), Positives = 15/24 (62%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAV 26 YD A+ FS G L+ V YA EAV Sbjct: 88 YDTALKAFSYGGKLYGVPYAMEAV 111 >5LF3-J nrPDB Length = 201 Score = 27.7 bits (60), Expect = 5.4, Method: Compositional matrix adjust. Identities = 16/54 (29%), Positives = 23/54 (42%) Query: 124 RRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYT 177 R P+ ++ L+ G+D P LY D A G GA L++ YT Sbjct: 95 RTPYHVNLLLAGYDEHEGPALYYMDYLAALAKAPFAAHGYGAFLTLSILDRYYT 148 >4HO7-A nrPDB Length = 179 Score = 27.3 bits (59), Expect = 6.6, Method: Compositional matrix adjust. Identities = 25/59 (42%), Positives = 32/59 (54%), Gaps = 13/59 (22%) Query: 25 AVKKGSTAVGVRGKDIVVLG---VEKKSVAKLQDERTVRKICALDDNVCMAFAGLTADA 80 +V+KG T V + G V LG V K S KL R+I +D+V + FAG TADA Sbjct: 5 SVRKGDTVV-LLGDRQVTLGERIVAKSSACKL------RRI---NDDVVIGFAGSTADA 53 >6FAI-j nrPDB Length = 463 Score = 26.9 bits (58), Expect = 7.1, Method: Compositional matrix adjust. Identities = 33/136 (24%), Positives = 55/136 (40%), Gaps = 22/136 (16%) Query: 69 VCMAFAGLTADARIVINRAR-------VECQSHRLTVEDPVTVEYITRYIASLKQR---Y 118 + F+ + +V++R + +H L PV+ T A L+++ Sbjct: 1 MSKKFSSKNSQRYVVVHRPHDDPSFYDTDASAHVLV---PVSNPNKTSPEADLRKKDVSS 57 Query: 119 TQSNGRRPFGISALIVGFDFDGTPRLYQT-------DPSGT-YHAWKANAIGRGAKSVRE 170 T+ GRR A + G +FD + Y DP + + A K N K++ + Sbjct: 58 TKPKGRRAHVGEAALYGINFDDSEYDYTQHLKPIGLDPENSIFIASKGNEQKVEKKNIED 117 Query: 171 -FLEKNYTDDAIETDD 185 F+E Y D IE DD Sbjct: 118 LFIEPKYRRDEIEKDD 133 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5LEZ-C nrPDB 331 1e-91 6HE5-A nrPDB 282 6e-77 4YA5-C nrPDB 272 7e-74 5FMG-D nrPDB 271 2e-73 3H4P-A nrPDB 270 4e-73 5T0I-L nrPDB 263 6e-71 1IRU-A nrPDB 259 6e-70 2Z5C-C nrPDB 251 3e-67 2KU2-A nrPDB 250 4e-67 5GJR-F nrPDB 250 4e-67 5FMG-B nrPDB 249 8e-67 5LF0-A nrPDB 249 8e-67 5LE5-B nrPDB 249 1e-66 5FMG-E nrPDB 245 1e-65 1G0U-D nrPDB 243 5e-65 5FMG-F nrPDB 242 9e-65 6J30-C nrPDB 242 1e-64 5FMG-C nrPDB 238 2e-63 4FZC-A nrPDB 234 3e-62 6EPD-G nrPDB 230 3e-61 3NZW-E nrPDB 224 2e-59 5L5W-G nrPDB 222 9e-59 6FVW-g nrPDB 221 3e-58 5FMG-A nrPDB 220 3e-58 5FGG-F nrPDB 220 4e-58 3NZW-K nrPDB 198 2e-51 5CZ8-K nrPDB 192 1e-49 5FMG-G nrPDB 191 3e-49 6EPF-2 nrPDB 180 4e-46 5L4G-8 nrPDB 178 2e-45 3H4P-a nrPDB 177 4e-45 6EPF-5 nrPDB 177 6e-45 5FMG-I nrPDB 176 8e-45 6AVO-B nrPDB 172 1e-43 3UNH-H nrPDB 172 2e-43 3IPM-H nrPDB 171 3e-43 6HEC-1 nrPDB 165 2e-41 3UNB-K nrPDB 162 1e-40 5FGI-H nrPDB 161 2e-40 3WXR-K nrPDB 135 1e-32 5FGE-J nrPDB 135 1e-32 5FMG-K nrPDB 134 3e-32 5FMG-M nrPDB 133 7e-32 3NZW-L nrPDB 131 3e-31 Sequences not found previously or not previously below threshold: 5L64-K nrPDB 183 5e-47 6HUB-H nrPDB 172 9e-44 5LN3-5 nrPDB 170 5e-43 5L5A-K nrPDB 169 9e-43 6HV7-H nrPDB 153 7e-38 3UNF-K nrPDB 143 7e-35 6AVO-C nrPDB 143 8e-35 5FMG-L nrPDB 128 2e-30 6EPC-1 nrPDB 113 9e-26 5GJQ-a nrPDB 111 3e-25 5L4G-U nrPDB 110 4e-25 5VFT-S nrPDB 109 1e-24 6EPF-6 nrPDB 108 2e-24 5MPC-h nrPDB 106 7e-24 5LEZ-N nrPDB 105 3e-23 5LF3-J nrPDB 101 4e-22 6AVO-A nrPDB 95 3e-20 1Q5R-H nrPDB 93 8e-20 1Q5Q-H nrPDB 90 1e-18 3UNF-N nrPDB 85 3e-17 3UNE-I nrPDB 78 4e-15 4Y8P-I nrPDB 77 6e-15 2JAY-A nrPDB 76 1e-14 5FMG-J nrPDB 75 2e-14 5FMG-N nrPDB 75 4e-14 6GOP-M nrPDB 74 6e-14 5FMG-H nrPDB 69 2e-12 5LZP-A nrPDB 69 2e-12 5GJQ-g nrPDB 65 4e-11 5LF6-M nrPDB 63 1e-10 6EPE-7 nrPDB 60 1e-09 4HO7-A nrPDB 51 3e-07 5LOX-A nrPDB 48 3e-06 5LOY-A nrPDB 46 1e-05 5NYF-A nrPDB 44 5e-05 5JI2-A nrPDB 42 2e-04 5NYW-A nrPDB 40 8e-04 1OFH-G nrPDB 37 0.007 6DTT-A nrPDB 37 0.010 1M4Y-A nrPDB 33 0.16 2GHB-A nrPDB 31 0.36 4OQJ-A nrPDB 31 0.46 4W8N-A nrPDB 30 1.1 3QQE-A nrPDB 30 1.2 2WR7-A nrPDB 30 1.2 2PF1-A nrPDB 29 1.8 1G61-A nrPDB 29 2.0 3PFQ-A nrPDB 29 2.3 2E21-A nrPDB 29 2.3 2Z3B-A nrPDB 29 2.5 3MYR-A nrPDB 28 2.8 2WR0-A nrPDB 28 3.0 1JSO-A nrPDB 28 3.7 3GTD-A nrPDB 28 3.8 1KSU-A nrPDB 28 5.0 3TY6-A nrPDB 28 5.9 >5LEZ-C nrPDB Length = 248 Score = 331 bits (850), Expect = 1e-91, Method: Composition-based stats. Identities = 245/248 (98%), Positives = 247/248 (99%) Query: 1 MSYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVR 60 MSYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRG+DIVVLGVEKKSVAKLQDERTVR Sbjct: 1 MSYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTVR 60 Query: 61 KICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQ 120 KICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQ Sbjct: 61 KICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQ 120 Query: 121 SNGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDA 180 SNGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTD+A Sbjct: 121 SNGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDEA 180 Query: 181 IETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQPLKILNPEEIEKYVAEIEKEKEENE 240 IETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQ LKILNPEEIEKYVAEIEKEKEENE Sbjct: 181 IETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQSLKILNPEEIEKYVAEIEKEKEENE 240 Query: 241 KKKQKKAS 248 KKKQKKAS Sbjct: 241 KKKQKKAS 248 >6HE5-A nrPDB Length = 247 Score = 282 bits (723), Expect = 6e-77, Method: Composition-based stats. Identities = 110/236 (46%), Positives = 158/236 (66%), Gaps = 3/236 (1%) Query: 1 MSYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVR 60 M YDRAITVFSPDG LFQVEYA+EAVK+G+TA+G++ K+ V+L +K+ +KL + T+ Sbjct: 7 MGYDRAITVFSPDGRLFQVEYAREAVKRGATAIGIKCKEGVILIADKRVGSKLLEADTIE 66 Query: 61 KICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQ 120 KI +D+++C A +GL ADAR++I+RAR+E Q +RLT ++P+TV+ + + I KQ+YTQ Sbjct: 67 KIYKIDEHICAATSGLVADARVLIDRARIEAQINRLTYDEPITVKELAKKICDFKQQYTQ 126 Query: 121 SNGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDA 180 G RPFG+S LI G D P+LY+TDPSG +KA AIG G +V EF EK Y DD Sbjct: 127 YGGVRPFGVSLLIAGVDE--VPKLYETDPSGALLEYKATAIGMGRNAVTEFFEKEYRDDL 184 Query: 181 IETDDLTIKLVIKALLEVVQSGGKNIELAVMR-RDQPLKILNPEEIEKYVAEIEKE 235 D + + LV L + +NIE+ ++ D+ K ++PEE++ YV + Sbjct: 185 SFDDAMVLGLVAMGLSIESELVPENIEVGYVKVDDRTFKEVSPEELKPYVERANER 240 >4YA5-C nrPDB Length = 254 Score = 272 bits (697), Expect = 7e-74, Method: Composition-based stats. Identities = 137/234 (58%), Positives = 181/234 (77%), Gaps = 3/234 (1%) Query: 2 SYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDER-TVR 60 YDRA+++FSPDGH+FQVEYA EAVK+G+ AVGV+GK+ VVLG E++S KLQD R T Sbjct: 3 GYDRALSIFSPDGHIFQVEYALEAVKRGTCAVGVKGKNCVVLGCERRSTLKLQDTRITPS 62 Query: 61 KICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQ 120 K+ +D +V ++F+GL AD+RI+I +ARVE QSHRLT+EDPVTVEY+TRY+A ++QRYTQ Sbjct: 63 KVSKIDSHVVLSFSGLNADSRILIEKARVEAQSHRLTLEDPVTVEYLTRYVAGVQQRYTQ 122 Query: 121 SNGRRPFGISALIVGFD-FDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNY-TD 178 S G RPFG+S LI GFD D P+LYQT+PSG Y +W A IGR +K+VREFLEKNY Sbjct: 123 SGGVRPFGVSTLIAGFDPRDDEPKLYQTEPSGIYSSWSAQTIGRNSKTVREFLEKNYDRK 182 Query: 179 DAIETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQPLKILNPEEIEKYVAEI 232 + T + +KL +++LLEVVQ+G KNIE+ V++ D + L+ EEI +YV +I Sbjct: 183 EPPATVEECVKLTVRSLLEVVQTGAKNIEITVVKPDSDIVALSSEEINQYVTQI 236 >5FMG-D nrPDB Length = 241 Score = 271 bits (693), Expect = 2e-73, Method: Composition-based stats. Identities = 118/244 (48%), Positives = 173/244 (70%), Gaps = 3/244 (1%) Query: 1 MSYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVR 60 MSYDRAITVFSPDGHL QVE+A EAVKKG AV ++ + VL VEKK++ KLQ+ +T Sbjct: 1 MSYDRAITVFSPDGHLLQVEHALEAVKKGGCAVAIKSSNFAVLAVEKKNIPKLQNPKTTE 60 Query: 61 KICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQ 120 K+ LD++ C+AFAGL ADAR+++N+ R+ECQ + L +++P V+YI +Y+A ++Q++T Sbjct: 61 KLIKLDEHNCLAFAGLNADARVLVNKTRLECQRYYLNMDEPAPVDYIAKYVAKVQQKFTH 120 Query: 121 SNGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDA 180 G RPFGI+ LI GF + +YQT+PSG Y AWKA AIG+ AK V+EFLEKNY ++ Sbjct: 121 RGGVRPFGIATLIAGFKNNKEICIYQTEPSGIYAAWKAQAIGKNAKIVQEFLEKNYQENM 180 Query: 181 IETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQPLKILNPEEIEKYVAEIEKEKEENE 240 + D I L +KA+ EVV+ KN+E+A++ ++ L + +EI V I++E+ +N Sbjct: 181 EQKD--CIFLALKAIFEVVELSSKNVEVALLT-EKDLTFIEEQEINSMVELIDQERTKNN 237 Query: 241 KKKQ 244 ++ + Sbjct: 238 EQNE 241 >3H4P-A nrPDB Length = 264 Score = 270 bits (690), Expect = 4e-73, Method: Composition-based stats. Identities = 103/225 (45%), Positives = 150/225 (66%), Gaps = 5/225 (2%) Query: 2 SYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRK 61 +YDRAITVFSP+G L+QVEYA+EAV++G+TA+G+ KD VVL V+++ +KL R++ K Sbjct: 11 AYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITSKLVKIRSIEK 70 Query: 62 ICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQS 121 I +DD+V A +GL ADAR++I+RAR+E Q +RLT + +++E + + I +KQ YTQ Sbjct: 71 IFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQH 130 Query: 122 NGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAI 181 G RPFG+S LI G D + RL++TDPSG +KA AIG G V E LEK Y DD Sbjct: 131 GGVRPFGVSLLIAGIDKNEA-RLFETDPSGALIEYKATAIGSGRPVVMELLEKEYRDDI- 188 Query: 182 ETDDLTIKLVIKALLEVVQ-SGGKNIELAVMR-RDQPLKILNPEE 224 T D ++L I AL + + +N+++ ++ +D K + EE Sbjct: 189 -TLDEGLELAITALTKANEDIKPENVDVCIITVKDAQFKKIPVEE 232 >5T0I-L nrPDB Length = 268 Score = 263 bits (672), Expect = 6e-71, Method: Composition-based stats. Identities = 80/246 (32%), Positives = 139/246 (56%), Gaps = 7/246 (2%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRKI 62 YD +TV+SP G + Q+EYA EAVK+GS VG++ K VL K++ ++L + +KI Sbjct: 11 YDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQ--KKI 68 Query: 63 CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122 +D+++ ++ AGLTADAR++ N R EC R + P+ V + I S Q TQ Sbjct: 69 LHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRY 128 Query: 123 GRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIE 182 GRRP+G+ LI G+D D P ++QT PS Y +A +IG ++S R +LE++ ++ Sbjct: 129 GRRPYGVGLLIAGYD-DMGPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFMEC 187 Query: 183 TDDLTIKLVIKALLEVVQS----GGKNIELAVMRRDQPLKILNPEEIEKYVAEIEKEKEE 238 + +K ++AL E + + KN+ + ++ +D I + +++ ++ +E+ + Sbjct: 188 NLNELVKHGLRALRETLPAEQDLTTKNVSIGIVGKDLEFTIYDDDDVSPFLEGLEERPQR 247 Query: 239 NEKKKQ 244 + Q Sbjct: 248 KAQPAQ 253 >1IRU-A nrPDB Length = 246 Score = 259 bits (663), Expect = 6e-70, Method: Composition-based stats. Identities = 81/238 (34%), Positives = 128/238 (53%), Gaps = 4/238 (1%) Query: 2 SYDRAITVFSPDGHLFQVEYAQEAVKKGS-TAVGVRGKDIVVLGVEKKSVAKLQDERTVR 60 +DR IT+FSP+G L+QVEYA +A+ +G T+V VRGKD V+ +KK KL D TV Sbjct: 8 GFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVT 67 Query: 61 KICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQ 120 + + +N+ G+TAD+R + RAR E + + + V+ + + IA + Q YTQ Sbjct: 68 HLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQ 127 Query: 121 SNGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDA 180 + RP G +++G D + P++Y+ DP+G Y +KA A G FLEK Sbjct: 128 NAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKF 187 Query: 181 IETDDLTIKLVIKALLEVVQSGGK--NIELAVMRRDQP-LKILNPEEIEKYVAEIEKE 235 T + T++ I L V+ K IE+ V+ + P +IL EI+ ++ + + Sbjct: 188 DWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLVALAER 245 >2Z5C-C nrPDB Length = 262 Score = 251 bits (640), Expect = 3e-67, Method: Composition-based stats. Identities = 87/250 (34%), Positives = 143/250 (57%), Gaps = 11/250 (4%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRKI 62 YDR ++ FSP+G LFQVEY+ EA+K GSTA+G+ K+ VVLGVEK++ + L + ++ KI Sbjct: 10 YDRGVSTFSPEGRLFQVEYSLEAIKLGSTAIGIATKEGVVLGVEKRATSPLLESDSIEKI 69 Query: 63 CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122 +D ++ A +GLTADAR +I AR +H L ++ + VE +T+ + L R+ + Sbjct: 70 VEIDRHIGCAMSGLTADARSMIEHARTAAVTHNLYYDEDINVESLTQSVCDLALRFGEGA 129 Query: 123 G------RRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNY 176 RPFG++ LI G D D +L+ +PSGT++ + A AIG G++ + L + Sbjct: 130 SGEERLMSRPFGVALLIAGHDADDGYQLFHAEPSGTFYRYNAKAIGSGSEGAQAELLNEW 189 Query: 177 TDDAIETDDLTIKLVIKALLEVVQ--SGGKNIELAVMRRDQPLKILNPEEIEKYVAEIEK 234 + LV+K L +V++ N +L+ + + KI + E+ + + E+ K Sbjct: 190 HSSLTLKEAEL--LVLKILKQVMEEKLDENNAQLSCITKQDGFKIYDNEKTAELIKEL-K 246 Query: 235 EKEENEKKKQ 244 EKE E ++ Sbjct: 247 EKEAAESPEE 256 >2KU2-A nrPDB Length = 237 Score = 250 bits (639), Expect = 4e-67, Method: Composition-based stats. Identities = 96/231 (41%), Positives = 147/231 (63%), Gaps = 5/231 (2%) Query: 1 MSYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVR 60 M+ RAITVFSPDG LFQVEYA+EAVKKGSTA+G++ + V+L +KK ++L ++ ++ Sbjct: 10 MAGGRAITVFSPDGRLFQVEYAREAVKKGSTALGMKFANGVLLISDKKVRSRLIEQNSIE 69 Query: 61 KICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQ 120 KI +DD V +GL ADAR++++ AR+ Q ++T V +E + + +A Q+YTQ Sbjct: 70 KIQLIDDYVAAVTSGLVADARVLVDFARISAQQEKVTYGSLVNIENLVKRVADQMQQYTQ 129 Query: 121 SNGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDA 180 G RP+G+S + G D G PRL+ DP+GT + +KA AIG G +V FLE+ Y ++ Sbjct: 130 YGGVRPYGVSLIFAGIDQIG-PRLFDCDPAGTINEYKATAIGSGKDAVVSFLEREYKENL 188 Query: 181 IETDDLTIKLVIKALLEVVQSGG--KNIELAVMRRDQPLKILNPEEIEKYV 229 E + +T L IKAL ++ G K E+A + +I + EE++K++ Sbjct: 189 PEKEAVT--LGIKALKSSLEEGEELKAPEIASITVGNKYRIYDQEEVKKFL 237 >5GJR-F nrPDB Length = 241 Score = 250 bits (639), Expect = 4e-67, Method: Composition-based stats. Identities = 83/235 (35%), Positives = 137/235 (58%), Gaps = 6/235 (2%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRKI 62 YDR + FSP+G LFQVEYA EA+K GSTA+G++ + V L VEK+ + L + ++ KI Sbjct: 8 YDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLMEPSSIEKI 67 Query: 63 CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122 +D ++ A +GL ADA+ +I++ARVE Q+H T + +TVE +T+ +++L ++ + + Sbjct: 68 VEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLALQFGEED 127 Query: 123 G-----RRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYT 177 RPFG++ L G D G P+L+ DPSGT+ A AIG ++ + L++ Y Sbjct: 128 ADPGAMSRPFGVALLFGGVDEKG-PQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEVYH 186 Query: 178 DDAIETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQPLKILNPEEIEKYVAEI 232 + + L+I + + NIELA ++ Q + EE+E+ + +I Sbjct: 187 KSMTLKEAIKSSLIILKQVMEEKLNATNIELATVQPGQNFHMFTKEELEEVIKDI 241 >5FMG-B nrPDB Length = 235 Score = 249 bits (636), Expect = 8e-67, Method: Composition-based stats. Identities = 90/233 (38%), Positives = 131/233 (56%), Gaps = 5/233 (2%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRKI 62 Y ++T FSP G L Q+EYA V S A+G+R K+ V++ EKKS +L +E ++ KI Sbjct: 6 YSFSLTTFSPTGKLVQIEYALNRVSSSSPALGIRAKNGVIIATEKKSPNELIEENSIFKI 65 Query: 63 CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122 + +++ + +AG+ D R+++ RAR E + L + V+ + + IAS+ Q +TQ+ Sbjct: 66 QQISEHIGIVYAGMPGDFRVLLKRARKEAIRYSLQYGSEILVKELVKIIASIVQEFTQTG 125 Query: 123 GRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIE 182 G RPFG+S LI G D G LYQ DPSG Y W A +G+ ++ FLEK Y D Sbjct: 126 GVRPFGLSLLICGVDVYG-YHLYQIDPSGCYFNWMATCVGKDYQNNMSFLEKRYNKDIEI 184 Query: 183 TDDLTIKLVIKALLEVVQ--SGGKNIELAVMRRDQPLKILNPEEIEKYVAEIE 233 D I I L E + KNIE+ V ++P KIL EI+ Y+ EIE Sbjct: 185 ED--AIHTAILTLKESYEGVLNEKNIEIGVAYDNKPFKILTQNEIKDYLIEIE 235 >5LF0-A nrPDB Length = 234 Score = 249 bits (636), Expect = 8e-67, Method: Composition-based stats. Identities = 89/234 (38%), Positives = 136/234 (58%), Gaps = 6/234 (2%) Query: 2 SYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRK 61 Y ++T FSP G L Q+EYA AV G+ +VG++ + VVL EKK + L DER+V K Sbjct: 5 GYSFSLTTFSPSGKLVQIEYALAAVAGGAPSVGIKAANGVVLATEKKQKSILYDERSVHK 64 Query: 62 ICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQS 121 + + ++ + ++G+ D R++++RAR Q + L ++P+ + + +AS+ Q YTQS Sbjct: 65 VEPITKHIGLVYSGMGPDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYTQS 124 Query: 122 NGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAI 181 G RPFG+S LI G++ G P L+Q+DPSG Y AWKA A+G+ + + FLEK Y +D Sbjct: 125 GGVRPFGVSLLICGWNE-GRPYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNEDLE 183 Query: 182 ETDDLTIKLVIKALLEVV--QSGGKNIELAVMRRDQPLKILNPEEIEKYVAEIE 233 D I I L E Q NIE+ + + + L P E++ Y+A I Sbjct: 184 LED--AIHTAILTLKESFEGQMTEDNIEVGIC-NEAGFRRLTPTEVKDYLAAIA 234 >5LE5-B nrPDB Length = 261 Score = 249 bits (635), Expect = 1e-66, Method: Composition-based stats. Identities = 80/234 (34%), Positives = 137/234 (58%), Gaps = 8/234 (3%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTV-RK 61 YD T+FSP+G L+QVEYA EA+ T +G+ D V+L E++++ KL DE K Sbjct: 5 YDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEK 64 Query: 62 ICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQS 121 I L++++ + AG+T+DA ++ N R+ Q + L ++P+ E + + +KQ YTQ Sbjct: 65 IYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQF 124 Query: 122 NGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAI 181 G+RPFG+S L +G+D +LYQ+DPSG Y WKA IG + + L+++Y + + Sbjct: 125 GGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEM 184 Query: 182 ETDDLTIKLVIKAL---LEVVQSGGKNIELAVMRRDQP---LKILNPEEIEKYV 229 T + L IK L ++V + + +E+A + R+ +++L +E+E+ + Sbjct: 185 -TLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLI 237 >5FMG-E nrPDB Length = 256 Score = 245 bits (626), Expect = 1e-65, Method: Composition-based stats. Identities = 78/239 (32%), Positives = 133/239 (55%), Gaps = 11/239 (4%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRKI 62 YDR + FSP+G LFQVEYA A+K GSTAVG+ D V+L E++ + L ++ +V K+ Sbjct: 8 YDRGVNTFSPEGRLFQVEYALGAIKLGSTAVGICVNDGVILASERRISSTLIEKDSVEKL 67 Query: 63 CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122 ++DD++ A +GL ADAR +I+ ARVEC ++ + + ++ I+ L ++ + Sbjct: 68 LSIDDHIGCAMSGLMADARTLIDYARVECNHYKFIYNENINIKSCVELISELALDFSNLS 127 Query: 123 G-------RRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKN 175 RPFG++ LI G D +G P L+ T+PSGT + A +IG + L++N Sbjct: 128 DSKRKKIMSRPFGVALLIGGVDKNG-PCLWYTEPSGTNTRFSAASIGSAQEGAELLLQEN 186 Query: 176 YTDDAIETDDLTIKL-VIKALLEVVQSGGKNIELAVMRR-DQPLKILNPEEIEKYVAEI 232 Y D + L V++ ++E + N+E+ +++ DQ N ++I + + + Sbjct: 187 YKKDMTFEQAEILALTVLRQVMED-KLSTSNVEICAIKKSDQTFYKYNTDDISRIIDVL 244 >1G0U-D nrPDB Length = 241 Score = 243 bits (621), Expect = 5e-65, Method: Composition-based stats. Identities = 87/240 (36%), Positives = 139/240 (57%), Gaps = 8/240 (3%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRKI 62 YDR ++ FSP+G LFQVEY+ EA+K GSTA+G+ K+ VVLGVEK++ + L + ++ KI Sbjct: 8 YDRGVSTFSPEGRLFQVEYSLEAIKLGSTAIGIATKEGVVLGVEKRATSPLLESDSIEKI 67 Query: 63 CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122 +D ++ A +GLTADAR +I AR +H L ++ + VE +T+ + L S Sbjct: 68 VEIDRHIGCAMSGLTADARSMIEHARTAAVTHNLYYDEDINVESLTQSVCDLAAAAAMS- 126 Query: 123 GRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIE 182 RPFG++ LI G D D +L+ +PSGT++ + A AIG G++ + L + Sbjct: 127 --RPFGVALLIAGHDADDGYQLFHAEPSGTFYRYNAKAIGSGSEGAQAELLNEWHSSLTL 184 Query: 183 TDDLTIKLVIKALLEVVQ--SGGKNIELAVMRRDQPLKILNPEEIEKYVAEIEKEKEENE 240 + LV+K L +V++ N +L+ + + KI + E+ + + E+ KEKE E Sbjct: 185 KEAEL--LVLKILKQVMEEKLDENNAQLSCITKQDGFKIYDNEKTAELIKEL-KEKEAAE 241 >5FMG-F nrPDB Length = 254 Score = 242 bits (618), Expect = 9e-65, Method: Composition-based stats. Identities = 75/252 (29%), Positives = 146/252 (57%), Gaps = 10/252 (3%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRKI 62 YD ++SP+G L+QVEYA EA+K+G+ AV ++ KD VV+ KK ++KL + KI Sbjct: 6 YDTDNIIYSPEGRLYQVEYASEAIKQGTCAVAIKSKDYVVVSGLKKCISKLSFPQ--EKI 63 Query: 63 CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122 +DD + ++ +G+T+DA+++ + EC SH+ + + +E + R +A Q+ TQ + Sbjct: 64 FKIDDYIGISMSGITSDAKVLTKFMQNECLSHKFLYNENINIESLVRSVADKYQKNTQKS 123 Query: 123 GRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIE 182 +R FG+ +I + P +++T P+G+Y + A + G + + + +LEKN Sbjct: 124 SKRAFGVGLMIAAY--HNEPCIFETRPNGSYFEYDALSFGARSHASKTYLEKNLHLFEEC 181 Query: 183 TDDLTIKLVIKALLEVVQSGGK----NIELAVMRRDQPLKILNPEEIEKYVAEI--EKEK 236 + + I +KAL + S + N LAV+ ++ P + ++ ++E+Y++++ + E+ Sbjct: 182 SLEELILHCLKALKCSLSSESELTISNTALAVVGKNHPWQEISSLQLEEYLSKVKMDAEQ 241 Query: 237 EENEKKKQKKAS 248 E+ E+ Q +A+ Sbjct: 242 EQVEENVQNEAN 253 >6J30-C nrPDB Length = 258 Score = 242 bits (617), Expect = 1e-64, Method: Composition-based stats. Identities = 86/238 (36%), Positives = 134/238 (56%), Gaps = 11/238 (4%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERT-VRK 61 YD T+FSP+G L+QVEYA E++ TA+G+ D +VL E+K + L ++ T K Sbjct: 6 YDSRTTIFSPEGRLYQVEYALESISHAGTAIGIMASDGIVLAAERKVTSTLLEQDTSTEK 65 Query: 62 ICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQS 121 + L+D + +A AGLTADA I+IN AR+ Q++ T + + VE + R ++ +KQ YTQ Sbjct: 66 LYKLNDKIAVAVAGLTADAEILINTARIHAQNYLKTYNEDIPVEILVRRLSDIKQGYTQH 125 Query: 122 NGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAI 181 G RPFG+S + G+D +LY ++PSG Y WKA ++G + + L+ +Y DD Sbjct: 126 GGLRPFGVSFIYAGYDDRYGYQLYTSNPSGNYTGWKAISVGANTSAAQTLLQMDYKDDMK 185 Query: 182 ETDDLTIKLVIKALLEVVQSGG---KNIELAVMRRDQP-----LKILNPEEIEKYVAE 231 D I+L +K L + S +E A +R+ KI P+EI+ + + Sbjct: 186 VDD--AIELALKTLSKTTDSSALTYDRLEFATIRKGANDGEVYQKIFKPQEIKDILVK 241 >5FMG-C nrPDB Length = 246 Score = 238 bits (607), Expect = 2e-63, Method: Composition-based stats. Identities = 83/233 (35%), Positives = 121/233 (51%), Gaps = 5/233 (2%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDE-RTVRK 61 YD T FSP+G L+QVEYA EA+ S +G+ KD V+LG +K ++KL D+ K Sbjct: 5 YDSRTTTFSPEGRLYQVEYALEAINNASITIGLITKDGVILGADKVFISKLIDKANNYEK 64 Query: 62 ICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQS 121 I +D ++ AGL ADA I+IN++R+ Q + + V + I +KQ YTQ Sbjct: 65 IYKIDKHIFCGVAGLNADANILINQSRLYAQRYLYNYNEVQPVSQLVVQICDIKQSYTQY 124 Query: 122 NGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAI 181 G RP+G+S LI G+D +LY TDPSG Y W A AIG + L++ + +D Sbjct: 125 GGLRPYGVSFLIGGYDTKDGYQLYHTDPSGNYSGWFATAIGTNNLTASSVLKQEWKNDMT 184 Query: 182 ETDDLTIKLVIKALLEVVQS-GGKNIELAVMRRDQP---LKILNPEEIEKYVA 230 + L + L A + + IELA + K L +EIE+ + Sbjct: 185 LEEGLLLALKTLAKSTDTEIPKSEKIELAYLTNKDGEVYQKYLTEKEIEELIK 237 >4FZC-A nrPDB Length = 250 Score = 234 bits (596), Expect = 3e-62, Method: Composition-based stats. Identities = 80/248 (32%), Positives = 130/248 (52%), Gaps = 20/248 (8%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRKI 62 Y ++T FSP G L Q++YA AVK+G T++G++ + VV+ EKKS + L T+ K+ Sbjct: 5 YSFSLTTFSPSGKLGQIDYALTAVKQGVTSLGIKATNGVVIATEKKSSSPLAMSETLSKV 64 Query: 63 CALDDNVCMAFAGLTADARIVINRARVECQ-SHRLTVEDPVTVEYITRYIASLKQRYTQS 121 L ++ ++G+ D R++++++R S++ + + + +A + Q TQS Sbjct: 65 SLLTPDIGAVYSGMGPDYRVLVDKSRKVAHTSYKRIYGEYPPTKLLVSEVAKIMQEATQS 124 Query: 122 NGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAI 181 G RPFG+S LI G D LYQ DPSG+Y WKA AIG+G+ + + FLEK + D+ Sbjct: 125 GGVRPFGVSLLIAGHDEFNGFSLYQVDPSGSYFPWKATAIGKGSVAAKTFLEKRWNDELE 184 Query: 182 ETDDLTIKLVIKALLEVV--QSGGKNIELAVMRRDQP---------------LKILNPEE 224 D I + + L E V + G IELA++ + P + L +E Sbjct: 185 LED--AIHIALLTLKESVEGEFNGDTIELAIIGDENPDLLGYTGIPTDKGPRFRKLTSQE 242 Query: 225 IEKYVAEI 232 I + + Sbjct: 243 INDRLEAL 250 >6EPD-G nrPDB Length = 255 Score = 230 bits (588), Expect = 3e-61, Method: Composition-based stats. Identities = 81/254 (31%), Positives = 137/254 (53%), Gaps = 18/254 (7%) Query: 2 SYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRK 61 YD + + FSPDG +FQVEYA +AV+ STA+G+R KD VV GVEK ++KL +E + ++ Sbjct: 7 GYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKR 66 Query: 62 ICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQS 121 + +D +V MA AGL ADAR + + AR E + R + ++++ +A YT Sbjct: 67 LFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLY 126 Query: 122 NGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAI 181 + RPFG S ++ + + +LY DPSG + + AIG+ ++ + +EK + Sbjct: 127 SAVRPFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEK------L 180 Query: 182 ETDDLTIKLVIKALLEVV-----QSGGKNIELAVMRRDQPLKILNP-------EEIEKYV 229 + ++T + V+K + +++ + K EL + + K + EE EKY Sbjct: 181 QMKEMTCRDVVKEVAKIIYIVHDEVKDKAFELELSWVGELTKGRHEIVPKDVREEAEKYA 240 Query: 230 AEIEKEKEENEKKK 243 E KE++E++ Sbjct: 241 KESLKEEDESDDDN 254 >3NZW-E nrPDB Length = 234 Score = 224 bits (572), Expect = 2e-59, Method: Composition-based stats. Identities = 77/234 (32%), Positives = 122/234 (52%), Gaps = 10/234 (4%) Query: 2 SYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRK 61 +YD FSP G LFQVEYA EA+K+GS VG+R VL K++ +L + +K Sbjct: 5 NYDGDTVTFSPTGRLFQVEYALEAIKQGSVTVGLRSNTHAVLVALKRNADELSSYQ--KK 62 Query: 62 ICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQS 121 I D+++ ++ AGL DAR++ N R +C L + VE + Q+ TQS Sbjct: 63 IIKCDEHMGLSLAGLAPDARVLSNYLRQQCNYSSLVFNRKLAVERAGHLLCDKAQKNTQS 122 Query: 122 NGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAI 181 G RP+G+ LI+G+D G L + PSG AIG ++ + +LE+ D I Sbjct: 123 YGGRPYGVGLLIIGYDKSGA-HLLEFQPSGNVTELYGTAIGARSQGAKTYLERT-LDTFI 180 Query: 182 ETD---DLTIKLVIKALLEVVQSGG---KNIELAVMRRDQPLKILNPEEIEKYV 229 + D D IK ++A+ + ++ N+ +A++ +D P I + E + KY+ Sbjct: 181 KIDGNPDELIKAGVEAISQSLRDESLTVDNLSIAIVGKDTPFTIYDGEAVAKYI 234 >5L5W-G nrPDB Length = 252 Score = 222 bits (567), Expect = 9e-59, Method: Composition-based stats. Identities = 74/241 (30%), Positives = 122/241 (50%), Gaps = 9/241 (3%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGS-TAVGVRGKDIVVLGVEKKSVAKLQDERTVRK 61 YDR IT+FSP+G L+QVEYA +A + + ++ VRGKD V+ +KK KL D TV Sbjct: 12 YDRHITIFSPEGRLYQVEYAFKATNQTNINSLAVRGKDCTVVISQKKVPDKLLDPTTVSY 71 Query: 62 ICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQS 121 I + + M G DAR RA+ E R + + + + +A+L Q YTQ Sbjct: 72 IFCISRTIGMVVNGPIPDARNAALRAKAEAAEFRYKYGYDMPCDVLAKRMANLSQIYTQR 131 Query: 122 NGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAI 181 RP G+ V D + P +Y+TDP+G Y +KA A G + + LE ++ I Sbjct: 132 AYMRPLGVILTFVSVDEELGPSIYKTDPAGYYVGYKATATGPKQQEITTNLENHFKKSKI 191 Query: 182 -----ETDDLTIKLVIKALLEVV--QSGGKNIELAVMRRDQPLKILNPEEIEKYVAEIEK 234 E+ + ++ I +++ + + ++E+ V +D+ L+ E IE+ + I + Sbjct: 192 DHINEESWEKVVEFAITHMIDALGTEFSKNDLEVGVATKDKFFT-LSAENIEERLVAIAE 250 Query: 235 E 235 + Sbjct: 251 Q 251 >6FVW-g nrPDB Length = 245 Score = 221 bits (563), Expect = 3e-58, Method: Composition-based stats. Identities = 70/216 (32%), Positives = 112/216 (51%), Gaps = 9/216 (4%) Query: 2 SYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRK 61 YD + +VFSPDG FQVEYA +AV+ G+T++G++ D VV VEK +KL + K Sbjct: 4 GYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVK 63 Query: 62 ICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQS 121 I +D ++ ++GL D R ++NR R E S + + P+ + + Q +T Sbjct: 64 IQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLY 123 Query: 122 NGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAI 181 N RPFG+S + G D +G LY +PSG+Y +K A G+G +S + LEK Sbjct: 124 NSVRPFGVSTIFGGVDKNGA-HLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDH--- 179 Query: 182 ETDDLTIKLVIKALLEVVQS-----GGKNIELAVMR 212 + L+ + +K +++ K+ EL + Sbjct: 180 HPEGLSAREAVKQAAKIIYLAHEDNKEKDFELEISW 215 >5FMG-A nrPDB Length = 260 Score = 220 bits (562), Expect = 3e-58, Method: Composition-based stats. Identities = 76/251 (30%), Positives = 123/251 (49%), Gaps = 18/251 (7%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGS-TAVGVRGKDIVVLGVEKK------SVAKLQD 55 YDR +T+FSPDG+L+Q+EYA +AVK + T+VGV+G++ V+ +KK S KL D Sbjct: 9 YDRHLTIFSPDGNLYQIEYAIKAVKNTNITSVGVKGENCAVIISQKKMATQYISQDKLLD 68 Query: 56 ERTVRKICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLK 115 + I + D + + G+ D ++ +AR E + V E + R I Sbjct: 69 YNNITNIYNITDEIGCSMVGMPGDCLSMVYKARSEASEFLYSNGYNVNAETLCRNICDKI 128 Query: 116 QRYTQSNGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREF---- 171 Q YTQ R S +I+G D + P L++ DPSG ++A IG + Sbjct: 129 QVYTQHAYMRLHACSGMIIGIDENNKPELFKFDPSGFCAGYRACVIGNKEQESISVLERL 188 Query: 172 LEKNYTDDAIETDDLTIK----LVIKALLEVVQSG--GKNIELAVM-RRDQPLKILNPEE 224 LEK ET D I+ L I+AL ++ IE+A++ +++ ++ +E Sbjct: 189 LEKRKKKIQQETIDEDIRNTTILAIEALQTILAFDLKASEIEVAIVSTKNRNFTQISEKE 248 Query: 225 IEKYVAEIEKE 235 I+ Y+ I + Sbjct: 249 IDNYLTYIAER 259 >5FGG-F nrPDB Length = 288 Score = 220 bits (562), Expect = 4e-58, Method: Composition-based stats. Identities = 70/216 (32%), Positives = 112/216 (51%), Gaps = 9/216 (4%) Query: 2 SYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRK 61 YD + +VFSPDG FQVEYA +AV+ G+T++G++ D VV VEK +KL + K Sbjct: 7 GYDLSNSVFSPDGRNFQVEYAVKAVENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNVK 66 Query: 62 ICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQS 121 I +D ++ ++GL D R ++NR R E S + + P+ + + Q +T Sbjct: 67 IQVVDRHIGCVYSGLIPDGRHLVNRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLY 126 Query: 122 NGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAI 181 N RPFG+S + G D +G LY +PSG+Y +K A G+G +S + LEK Sbjct: 127 NSVRPFGVSTIFGGVDKNGA-HLYMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDH--- 182 Query: 182 ETDDLTIKLVIKALLEVVQS-----GGKNIELAVMR 212 + L+ + +K +++ K+ EL + Sbjct: 183 HPEGLSAREAVKQAAKIIYLAHEDNKEKDFELEISW 218 >3NZW-K nrPDB Length = 287 Score = 198 bits (503), Expect = 2e-51, Method: Composition-based stats. Identities = 43/218 (19%), Positives = 89/218 (40%), Gaps = 8/218 (3%) Query: 26 VKKGSTAVGVRGKDIVVLGVEKKSV-AKLQDERTVRKICALDDNVCMAFAGLTADARIVI 84 + G+T + R + +++ V+ ++ +TV+K+ ++ + AG AD + Sbjct: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 Query: 85 NRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRL 144 +C+ H L ++ ++V ++ +++L +Y + + +I G+ P + Sbjct: 132 TWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAG----LSMGTMICGYTRKEGPTI 187 Query: 145 YQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIETDDLTI--KLVIKALLEVVQSG 202 Y D GT +G G L+ NY D D L + + ++ A SG Sbjct: 188 YYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSG 247 Query: 203 GKNIELAVMRRDQPLKILNPEEIEKYVAEIEKEKEENE 240 G + L + D + N + E + E+E N Sbjct: 248 GS-VNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNN 284 >5CZ8-K nrPDB Length = 221 Score = 192 bits (489), Expect = 1e-49, Method: Composition-based stats. Identities = 42/218 (19%), Positives = 88/218 (40%), Gaps = 8/218 (3%) Query: 26 VKKGSTAVGVRGKDIVVLGVEKKSV-AKLQDERTVRKICALDDNVCMAFAGLTADARIVI 84 + G+T + R + +++ V+ ++ +TV+ + ++ + AG AD + Sbjct: 6 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKAVIEINPFLLGTMAGGAADCQFWE 65 Query: 85 NRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRL 144 +C+ H L ++ ++V ++ +++L +Y + + +I G+ P + Sbjct: 66 TWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAG----LSMGTMICGYTRKEGPTI 121 Query: 145 YQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIETDDLTI--KLVIKALLEVVQSG 202 Y D GT +G G L+ NY D D L + + ++ A SG Sbjct: 122 YYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSG 181 Query: 203 GKNIELAVMRRDQPLKILNPEEIEKYVAEIEKEKEENE 240 G + L + D + N + E + E+E N Sbjct: 182 GS-VNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNN 218 >5FMG-G nrPDB Length = 252 Score = 191 bits (485), Expect = 3e-49, Method: Composition-based stats. Identities = 60/246 (24%), Positives = 113/246 (45%), Gaps = 15/246 (6%) Query: 2 SYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSV--AKLQDERTV 59 YD +++ FSPDG L+QVEY +++ +TA+ + KD ++ ++ K+ + + Sbjct: 7 GYDLSVSTFSPDGRLYQVEYIYKSINNNNTALCLECKDGIICCCINSNMDKNKMIKKNSY 66 Query: 60 RKICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYT 119 +I +++N+ + ++G DAR +I+RAR E ++ + + + I+ YT Sbjct: 67 NRIYHVNNNIIITYSGFDGDARNIIDRARSEANTYYYNFHTNIPLHILVNRISLYIHAYT 126 Query: 120 QSNGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDD 179 RPF S +I F+ +Y +P+G + + IG+ + + +EK D Sbjct: 127 LYWHMRPFAASIIISSFNEKDKGDIYCIEPNGACYKYSGIVIGKNKEMFKTEIEKKDYKD 186 Query: 180 AIETDDLTIKLVIKALLEVVQSGGKN-----IELAVMRRDQPLKILN-PEEI-----EKY 228 D I+ + K +L KN + + + ++ + N EEI K Sbjct: 187 INVRD--AIEDIYKFILTSDDHMNKNNLQNLVNFSWICKESSYEFQNIHEEILTPALNKA 244 Query: 229 VAEIEK 234 V IEK Sbjct: 245 VEYIEK 250 >5L64-K nrPDB Length = 211 Score = 183 bits (466), Expect = 5e-47, Method: Composition-based stats. Identities = 42/214 (19%), Positives = 88/214 (41%), Gaps = 9/214 (4%) Query: 30 STAVGVRGKDIVVLGVEKKSV-AKLQDERTVRKICALDDNVCMAFAGLTADARIVINRAR 88 +T + + + V++ + ++ +TV+K+ ++ + AG AD Sbjct: 1 TTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLA 60 Query: 89 VECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQTD 148 +C+ + L ++ ++V ++ +A++ +Y + +I G+D G P LY D Sbjct: 61 RQCRIYELRNKERISVAAASKLLANMVYQYKGMG----LSMGTMICGWDKRG-PGLYYVD 115 Query: 149 PSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIETDDLTI--KLVIKALLEVVQSGGKNI 206 G + ++G G+ L+ NY D D L + + ++ A SGG + Sbjct: 116 SEGNRISGATFSVGSGSVYAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGS-V 174 Query: 207 ELAVMRRDQPLKILNPEEIEKYVAEIEKEKEENE 240 L + D + N + E + E+E N Sbjct: 175 NLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNN 208 >6EPF-2 nrPDB Length = 277 Score = 180 bits (458), Expect = 4e-46, Method: Composition-based stats. Identities = 49/205 (23%), Positives = 82/205 (40%), Gaps = 11/205 (5%) Query: 24 EAVKKGSTAVGVRGKDIVVLGVEKKSV-AKLQDERTVRKICALDDNVCMAFAGLTADARI 82 +A K G+T GV KD +VLG + ++ + ++ KI + N+ AG AD + Sbjct: 38 KARKTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDM 97 Query: 83 VINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTP 142 + H LT V R + + RY G + ++ G D G P Sbjct: 98 TTQLISSNLELHSLTTGRLPRVVTANRMLKQMLFRYQGY-----IGAALVLGGVDVTG-P 151 Query: 143 RLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIETDD--LTIKLVIKALLEVVQ 200 LY P G+ +G G+ + E + D E + L + + + + Sbjct: 152 HLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKKLVSEAIAAGIFNDLG 211 Query: 201 SGGKNIELAVMRRDQPLKILNPEEI 225 S G NI+L V+ + + L L P + Sbjct: 212 S-GSNIDLCVISKSK-LDFLRPYSV 234 >5L4G-8 nrPDB Length = 277 Score = 178 bits (451), Expect = 2e-45, Method: Composition-based stats. Identities = 47/205 (22%), Positives = 83/205 (40%), Gaps = 11/205 (5%) Query: 24 EAVKKGSTAVGVRGKDIVVLGVEKKSV-AKLQDERTVRKICALDDNVCMAFAGLTADARI 82 + K G+T GV KD +VLG + ++ + ++ KI + N+ AG AD + Sbjct: 38 KVRKTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDM 97 Query: 83 VINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTP 142 + H L+ V R + + RY G + ++ G D G P Sbjct: 98 TTQLISSNLELHSLSTGRLPRVVTANRMLKQMLFRYQGY-----IGAALVLGGVDVTG-P 151 Query: 143 RLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIETD--DLTIKLVIKALLEVVQ 200 LY P G+ +G G+ + E + D E + +L + + + + Sbjct: 152 HLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIFNDLG 211 Query: 201 SGGKNIELAVMRRDQPLKILNPEEI 225 S G NI+L V+ +++ L L P + Sbjct: 212 S-GSNIDLCVISKNK-LDFLRPYTV 234 >3H4P-a nrPDB Length = 219 Score = 177 bits (449), Expect = 4e-45, Method: Composition-based stats. Identities = 52/203 (25%), Positives = 93/203 (45%), Gaps = 8/203 (3%) Query: 30 STAVGVRGKDIVVLGVEKK-SVAKLQDERTVRKICALDDNVCMAFAGLTADARIVINRAR 88 +T VG+ D V+L +K+ S+ L ++ +K+ +DD + M AG DA+ ++ Sbjct: 2 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 61 Query: 89 VECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQTD 148 E + +++ + ++++ S+ PF +I G+D +L+ D Sbjct: 62 AEAKLYKMRTGRNIPPLACATLLSNILH----SSRMFPFLTQIIIGGYDLLEGAKLFSLD 117 Query: 149 PSGTYHAWK-ANAIGRGAKSVREFLEKNYTDDAIETDDLTIKL-VIKALLEVVQSGGKNI 206 P G + K A G G+ LE Y D + + + L +K+ +E G I Sbjct: 118 PLGGMNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGI 177 Query: 207 ELAVMRRDQPLKILNPEEIEKYV 229 LAV+ +D +KI EEIEK + Sbjct: 178 SLAVITKD-GVKIFEDEEIEKIL 199 >6EPF-5 nrPDB Length = 263 Score = 177 bits (448), Expect = 6e-45, Method: Composition-based stats. Identities = 38/204 (18%), Positives = 89/204 (43%), Gaps = 9/204 (4%) Query: 28 KGSTAVGVRGKDIVVLGVEKKSV-AKLQDERTVRKICALDDNVCMAFAGLTADARIVINR 86 G+T + + + V++ + ++ +TV+K+ ++ + AG AD Sbjct: 58 HGTTTLAFKFQHGVIVAADSRATAGPYIASQTVKKVIEINPYLLGTMAGGAADCSFWERL 117 Query: 87 ARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQ 146 +C+ + L ++ ++V ++ +A++ +Y + +I G+D G P LY Sbjct: 118 LARQCRIYELRNKERISVAAASKLLANMVYQYKGMG----LSMGTMICGWDKRG-PGLYY 172 Query: 147 TDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIETD--DLTIKLVIKALLEVVQSGGK 204 D G + A ++G G+ +++ Y+ D + DL + + +A SGG Sbjct: 173 VDSEGNRISGTAFSVGSGSVYAFGVMDRGYSYDLQVEEAYDLARRAIYQATYRDAYSGGA 232 Query: 205 NIELAVMRRDQPLKILNPEEIEKY 228 + L +R D +++ + + + Sbjct: 233 -VNLYHVREDGWIRVSSDNVADLH 255 >5FMG-I nrPDB Length = 229 Score = 176 bits (446), Expect = 8e-45, Method: Composition-based stats. Identities = 43/198 (21%), Positives = 86/198 (43%), Gaps = 10/198 (5%) Query: 30 STAVGVRGKDIVVLGVEKKSV-AKLQDERTVRKICALDDNVCMAFAGLTADARIVINRAR 88 +T G+ ++ V+LG + ++ + ++ K+ + N+ A AG+ D + Sbjct: 1 TTICGLVCQNAVILGADTRATEGPIVADKNCSKLHYISKNIWCAGAGVAGDLEHTTLWLQ 60 Query: 89 VECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQTD 148 + HRL V + ++ L Q + G + + ++ G D +G P+LY Sbjct: 61 HNVELHRLNTNTQPRV---SMCVSRLTQELFKYQGYKV--CAIVLGGVDVNG-PQLYGIH 114 Query: 149 PSGTYHAWKANAIGRGAKSVREFLEKNYTDDA--IETDDLTIKLVIKALLEVVQSGGKNI 206 P G+ A+G G+ + LE Y D+ E +L + + + + SGG N+ Sbjct: 115 PHGSSCLLPFTALGSGSLNAMAVLEAKYRDNMTIEEGKNLVCEAICAGIFNDLGSGG-NV 173 Query: 207 ELAVMRRDQPLKILNPEE 224 ++ V+ +D I +E Sbjct: 174 DICVITKDSYQHIRPYKE 191 >6HUB-H nrPDB Length = 234 Score = 172 bits (437), Expect = 9e-44, Method: Composition-based stats. Identities = 46/199 (23%), Positives = 81/199 (40%), Gaps = 11/199 (5%) Query: 30 STAVGVRGKDIVVLGVEKKSV-AKLQDERTVRKICALDDNVCMAFAGLTADARIVINRAR 88 +T GV KD +VLG + ++ + ++ KI + N+ AG AD + Sbjct: 1 TTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLIS 60 Query: 89 VECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQTD 148 + H L+ V R + + RY G + ++ G D G P LY Sbjct: 61 SNLELHSLSTGRLPRVVTANRMLKQMLFRYQGY-----IGAALVLGGVDVTG-PHLYSIY 114 Query: 149 PSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIETD--DLTIKLVIKALLEVVQSGGKNI 206 P G+ +G G+ + E + D E + +L + + + + SGG NI Sbjct: 115 PHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGSGG-NI 173 Query: 207 ELAVMRRDQPLKILNPEEI 225 +L V+ +++ L L P + Sbjct: 174 DLCVISKNK-LDFLRPYTV 191 >6AVO-B nrPDB Length = 234 Score = 172 bits (437), Expect = 1e-43, Method: Composition-based stats. Identities = 45/187 (24%), Positives = 82/187 (43%), Gaps = 10/187 (5%) Query: 30 STAVGVRGKDIVVLGVEKKSVAK-LQDERTVRKICALDDNVCMAFAGLTADARIVINRAR 88 +T G+ +D V+LG + ++ + +++ KI + + AG+ ADA + Sbjct: 1 TTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADAEMTTRMVA 60 Query: 89 VECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQTD 148 + + H L+ V +TR L+Q + G G S ++ G D G P+LY Sbjct: 61 SKMELHALSTGREPRVATVTRI---LRQTLFRYQGH--VGASLIVGGVDLTG-PQLYGVH 114 Query: 149 PSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIETDD--LTIKLVIKALLEVVQSGGKNI 206 P G+Y A+G G + LE + + L ++ V +L + SGG N+ Sbjct: 115 PHGSYSRLPFTALGSGQDAALAVLEDRFQPNMTLEAAQGLLVEAVTAGILGDLGSGG-NV 173 Query: 207 ELAVMRR 213 + V+ + Sbjct: 174 DACVITK 180 >3UNH-H nrPDB Length = 234 Score = 172 bits (435), Expect = 2e-43, Method: Composition-based stats. Identities = 44/189 (23%), Positives = 84/189 (44%), Gaps = 10/189 (5%) Query: 30 STAVGVRGKDIVVLGVEKKSVAK-LQDERTVRKICALDDNVCMAFAGLTADARIVINRAR 88 +T G+ +D V+LG + ++ + +++ KI + + AG+ AD + A Sbjct: 1 TTIAGLVFRDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADTEMTTRMAA 60 Query: 89 VECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQTD 148 + + H L+ V +TR L+Q + G G S ++ G D +G P+LY+ Sbjct: 61 SKMELHALSTGREPRVATVTRI---LRQTLFRYQGH--VGASLVVGGVDLNG-PQLYEVH 114 Query: 149 PSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIET--DDLTIKLVIKALLEVVQSGGKNI 206 P G+Y A+G G + LE + + +L ++ + +L + SGG N+ Sbjct: 115 PHGSYSRLPFTALGSGQGAAVALLEDRFQPNMTLEAAQELLVEAITAGILSDLGSGG-NV 173 Query: 207 ELAVMRRDQ 215 + V+ Sbjct: 174 DACVITAGG 182 >3IPM-H nrPDB Length = 217 Score = 171 bits (433), Expect = 3e-43, Method: Composition-based stats. Identities = 45/211 (21%), Positives = 93/211 (44%), Gaps = 8/211 (3%) Query: 24 EAVKKGSTAVGVRGKDIVVLGVEKKSV-AKLQDERTVRKICALDDNVCMAFAGLTADARI 82 + ++ G+T VG+ KD V++ E++ + +K+ +D M AGL DA++ Sbjct: 3 QTLETGTTTVGITLKDAVIMATERRVTMENFIMHKNGKKLFQIDTYTGMTIAGLVGDAQV 62 Query: 83 VINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTP 142 ++ + E + +RL + +E +A+L P+ + L+ G D P Sbjct: 63 LVRYMKAELELYRLQRRVNMPIEA----VATLLSNMLNQVKYMPYMVQLLVGGIDT--AP 116 Query: 143 RLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIETDDLTIKL-VIKALLEVVQS 201 ++ D +G + G G+ V LE Y++ + + + + I A + + Sbjct: 117 HVFSIDAAGGSVEDIYASTGSGSPFVYGVLESQYSEKMTVDEGVDLVIRAISAAKQRDSA 176 Query: 202 GGKNIELAVMRRDQPLKILNPEEIEKYVAEI 232 G I++AV+ R L ++IE + ++ Sbjct: 177 SGGMIDVAVITRKDGYVQLPTDQIESRIRKL 207 >5LN3-5 nrPDB Length = 263 Score = 170 bits (431), Expect = 5e-43, Method: Composition-based stats. Identities = 37/204 (18%), Positives = 87/204 (42%), Gaps = 9/204 (4%) Query: 28 KGSTAVGVRGKDIVVLGVEKKSV-AKLQDERTVRKICALDDNVCMAFAGLTADARIVINR 86 G+T + + + V++ + ++ +TV+K+ ++ + AG AD Sbjct: 58 HGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERL 117 Query: 87 ARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQ 146 +C+ + L ++ ++V ++ +A++ +Y + +I G+D G P LY Sbjct: 118 LARQCRIYELRNKERISVAAASKLLANMVYQYKGMG----LSMGTMICGWDKRG-PGLYY 172 Query: 147 TDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIET--DDLTIKLVIKALLEVVQSGGK 204 D G + ++G G+ +++ Y+ D DL + + +A SGG Sbjct: 173 VDSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGA 232 Query: 205 NIELAVMRRDQPLKILNPEEIEKY 228 + L +R D +++ + + + Sbjct: 233 -VNLYHVREDGWIRVSSDNVADLH 255 >5L5A-K nrPDB Length = 211 Score = 169 bits (429), Expect = 9e-43, Method: Composition-based stats. Identities = 43/214 (20%), Positives = 85/214 (39%), Gaps = 9/214 (4%) Query: 30 STAVGVRGKDIVVLGVEKK-SVAKLQDERTVRKICALDDNVCMAFAGLTADARIVINRAR 88 +T + + + V+ V+ + S V K+ ++ + +G AD + Sbjct: 1 TTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWETLLA 60 Query: 89 VECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQTD 148 EC+ + L + ++V ++ ++++ +Y + ++I G+D G P LY D Sbjct: 61 KECRLYYLRNGERISVSAASKLLSNMMCQYRGMG----LSMGSMICGWDKKG-PGLYYVD 115 Query: 149 PSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIETDDLTI--KLVIKALLEVVQSGGKNI 206 GT + + G G L+ NY D D L + + ++ A SGG + Sbjct: 116 EHGTRLSGNMFSTGSGNTYAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGS-V 174 Query: 207 ELAVMRRDQPLKILNPEEIEKYVAEIEKEKEENE 240 L + D + N + E + E+E N Sbjct: 175 NLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNN 208 >6HEC-1 nrPDB Length = 202 Score = 165 bits (417), Expect = 2e-41, Method: Composition-based stats. Identities = 54/210 (25%), Positives = 95/210 (45%), Gaps = 13/210 (6%) Query: 30 STAVGVRGKDIVVLGVEKKSV-AKLQDERTVRKICALDDNVCMAFAGLTADARIVINRAR 88 +T VG+ KD VV+ EK++ + +KI + D + M AG DA+ + + Sbjct: 1 TTTVGLVCKDGVVMATEKRATMGNFIASKAAKKIYQIADRMAMTTAGSVGDAQFLARIIK 60 Query: 89 VECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQTD 148 +E + + E TV R IA+L S P+ + LI G D +G +Y D Sbjct: 61 IEANLYEIRRERKPTV----RAIATLTSNLLNSYRYFPYLVQLLIGGIDSEGK-SIYSID 115 Query: 149 P-SGTYHAWKANAIGRGAKSVREFLEKNYTDDAIETDDLTIKLVIKALLEVVQ---SGGK 204 P G A G G+ + LE +T + D ++L ++A+ ++ + G Sbjct: 116 PIGGAIEEKDIVATGSGSLTAYGVLEDRFTPEI--GVDEAVELAVRAIYSAMKRDSASGD 173 Query: 205 NIELAVMRRDQPLKILNPEEIEKYVAEIEK 234 I++ + D+ +PEE+E+ +A+ K Sbjct: 174 GIDVVKITEDE-FYQYSPEEVEQILAKFRK 202 >3UNB-K nrPDB Length = 205 Score = 162 bits (410), Expect = 1e-40, Method: Composition-based stats. Identities = 38/202 (18%), Positives = 87/202 (43%), Gaps = 9/202 (4%) Query: 30 STAVGVRGKDIVVLGVEKKSV-AKLQDERTVRKICALDDNVCMAFAGLTADARIVINRAR 88 +T + + V++ + ++ +TV+K+ ++ + AG AD Sbjct: 1 TTTLAFKFLHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLA 60 Query: 89 VECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQTD 148 +C+ + L ++ ++V ++ +A++ +Y + +I G+D G P LY D Sbjct: 61 RQCRIYELRNKERISVAAASKLLANMVYQYKGMG----LSMGTMICGWDKRG-PGLYYVD 115 Query: 149 PSGTYHAWKANAIGRGAKSVREFLEKNYTDDA--IETDDLTIKLVIKALLEVVQSGGKNI 206 G + A ++G G+ +++ Y+ D E DL + + +A SGG + Sbjct: 116 SEGNRISGTAFSVGSGSVYAYGVMDRGYSYDLKVEEAYDLARRAIYQATYRDAYSGGA-V 174 Query: 207 ELAVMRRDQPLKILNPEEIEKY 228 L +R D +++ + + + Sbjct: 175 NLYHVREDGWIRVSSDNVADLH 196 >5FGI-H nrPDB Length = 244 Score = 161 bits (408), Expect = 2e-40, Method: Composition-based stats. Identities = 44/219 (20%), Positives = 89/219 (40%), Gaps = 14/219 (6%) Query: 24 EAVKKGSTAVGVRGKDIVVLGVEKKSV-AKLQDERTVRKICALDDNVCMAFAGLTADARI 82 +A G+T VGV+ + VV+ + +S + ++ K+ + + A AG AD Sbjct: 7 KATSTGATIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEA 66 Query: 83 VINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTP 142 V + H L V + LKQ + G G ++ G D G+ Sbjct: 67 VTQLIGSNIELHSLYTSREPRV---VSALQMLKQHLFKYQGH--IGAYLIVAGVDPTGS- 120 Query: 143 RLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIETDDLTIKL-VIKALLEVVQS 201 L+ G+ ++G G+ + LE ++ D + + + + I+A + Sbjct: 121 HLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLG 180 Query: 202 GGKNIELAVMRRDQPLKILNPEEIEKYVA-EIEKEKEEN 239 G N+++ VM + + E + Y+ + +EK+++ Sbjct: 181 SGSNVDVCVMEIGK-----DAEYLRNYLTPNVREEKQKS 214 >6HV7-H nrPDB Length = 226 Score = 153 bits (386), Expect = 7e-38, Method: Composition-based stats. Identities = 42/213 (19%), Positives = 88/213 (41%), Gaps = 14/213 (6%) Query: 30 STAVGVRGKDIVVLGVEKKSVAK-LQDERTVRKICALDDNVCMAFAGLTADARIVINRAR 88 +T G+ +D V+LG + ++ + +++ KI + + AG+ ADA V Sbjct: 1 TTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADAEAVTQLIG 60 Query: 89 VECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQTD 148 + H L V + LKQ + G G ++ G D G+ L+ Sbjct: 61 SNIELHSLYTSREPRV---VSALQMLKQHLFKYQGH--IGAYLIVAGVDPTGS-HLFSIH 114 Query: 149 PSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIETDDLTIKL-VIKALLEVVQSGGKNIE 207 G+ ++G G+ + LE ++ D + + + + I+A + G N++ Sbjct: 115 AHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVD 174 Query: 208 LAVMRRDQPLKILNPEEIEKYVA-EIEKEKEEN 239 + VM + + E + Y+ + +EK+++ Sbjct: 175 VCVMEIGK-----DAEYLRNYLTPNVREEKQKS 202 >3UNF-K nrPDB Length = 204 Score = 143 bits (361), Expect = 7e-35, Method: Composition-based stats. Identities = 37/208 (17%), Positives = 85/208 (40%), Gaps = 9/208 (4%) Query: 30 STAVGVRGKDIVVLGVEKKSV-AKLQDERTVRKICALDDNVCMAFAGLTADARIVINRAR 88 +T + + + V++ V+ ++ + K+ ++ + +G AD + Sbjct: 1 TTTLAFKFQHGVIVAVDSRATAGSYISSLRMNKVIEINPYLLGTMSGCAADCQYWERLLA 60 Query: 89 VECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQTD 148 EC+ + L + ++V ++ ++++ +Y + ++I G+D G P LY D Sbjct: 61 KECRLYYLRNGERISVSAASKLLSNMMLQYRGMG----LSMGSMICGWDKKG-PGLYYVD 115 Query: 149 PSGTYHAWKANAIGRGAKSVREFLEKNYTDDA--IETDDLTIKLVIKALLEVVQSGGKNI 206 +GT + + + G G ++ Y D E DL + + A SGG + Sbjct: 116 DNGTRLSGQMFSTGSGNTYAYGVMDSGYRQDLSPEEAYDLGRRAIAYATHRDNYSGGV-V 174 Query: 207 ELAVMRRDQPLKILNPEEIEKYVAEIEK 234 + M+ D +K+ + + + E Sbjct: 175 NMYHMKEDGWVKVESSDVSDLLYKYGEA 202 >6AVO-C nrPDB Length = 204 Score = 143 bits (360), Expect = 8e-35, Method: Composition-based stats. Identities = 37/211 (17%), Positives = 84/211 (39%), Gaps = 10/211 (4%) Query: 30 STAVGVRGKDIVVLGVEKK-SVAKLQDERTVRKICALDDNVCMAFAGLTADARIVINRAR 88 +T + + + V+ V+ + S V K+ ++ + +G AD + Sbjct: 1 TTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWERLLA 60 Query: 89 VECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQTD 148 EC+ + L + ++V ++ ++++ +Y + ++I G+D G P LY D Sbjct: 61 KECRLYYLRNGERISVSAASKLLSNMMCQYRGMG----LSMGSMICGWDKKG-PGLYYVD 115 Query: 149 PSGTYHAWKANAIGRGAKSVREFLEKNYTDDA--IETDDLTIKLVIKALLEVVQSGGKNI 206 GT + + G G ++ Y + E DL + + A SGG + Sbjct: 116 EHGTRLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDSYSGGV-V 174 Query: 207 ELAVMRRDQPLKILNPEEIEKYVAEIEKEKE 237 + M+ D +K+ ++ + + + + Sbjct: 175 NMYHMKEDGWVKV-ESTDVSDLLHQYREANQ 204 >3WXR-K nrPDB Length = 238 Score = 135 bits (341), Expect = 1e-32, Method: Composition-based stats. Identities = 41/188 (21%), Positives = 79/188 (42%), Gaps = 7/188 (3%) Query: 32 AVGVRGKDIVVLGVEKKSV-AKLQDERTVRKICALDDNVCMAFAGLTADARIVINRARVE 90 +G+R +D V+L K + + K L + M+FAG D + Sbjct: 4 ILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQAN 63 Query: 91 CQSHRLTVEDPVTVEYITRYIASLKQRYTQS-NGRRPFGISALIVGFDFD-GTPRLYQTD 148 Q + + + ++ + ++ ++ +Q +S RRP+ ++ LI G+D P LYQ D Sbjct: 64 IQLYSIREDYELSPQAVSSFV---RQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQID 120 Query: 149 PSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIETDDL-TIKLVIKALLEVVQSGGKNIE 207 GT A G L+ +Y D + L +KL ++ L + + K + Sbjct: 121 YLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVI 180 Query: 208 LAVMRRDQ 215 + ++ +D Sbjct: 181 VKIVDKDG 188 >5FGE-J nrPDB Length = 198 Score = 135 bits (341), Expect = 1e-32, Method: Composition-based stats. Identities = 41/188 (21%), Positives = 79/188 (42%), Gaps = 7/188 (3%) Query: 32 AVGVRGKDIVVLGVEKKSV-AKLQDERTVRKICALDDNVCMAFAGLTADARIVINRARVE 90 +G+R +D V+L K + + K L + M+FAG D + Sbjct: 4 ILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQAN 63 Query: 91 CQSHRLTVEDPVTVEYITRYIASLKQRYTQS-NGRRPFGISALIVGFDFD-GTPRLYQTD 148 Q + + + ++ + ++ ++ +Q +S RRP+ ++ LI G+D P LYQ D Sbjct: 64 IQLYSIREDYELSPQAVSSFV---RQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQID 120 Query: 149 PSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIETDDL-TIKLVIKALLEVVQSGGKNIE 207 GT A G L+ +Y D + L +KL ++ L + + K + Sbjct: 121 YLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVI 180 Query: 208 LAVMRRDQ 215 + ++ +D Sbjct: 181 VKIVDKDG 188 >5FMG-K nrPDB Length = 195 Score = 134 bits (338), Expect = 3e-32, Method: Composition-based stats. Identities = 42/193 (21%), Positives = 72/193 (37%), Gaps = 6/193 (3%) Query: 31 TAVGVRGKDIVVLGVEKKSVAKLQDERT--VRKICALDDNVCMAFAGLTADARIVINRAR 88 T +G+RG + VVL + S+ + + K + N C+ G D R Sbjct: 3 TLIGLRGNNFVVLAADTYSINSIIKLKNDDNTKFYDIHGNKCLLLGGSIGDRLQFGEFIR 62 Query: 89 VECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQTD 148 ++ + V+ + ++ R PF ++ LI G+D +LY D Sbjct: 63 KNVHLYQYQNNTDMFVKSFAFFT---RKNLAYYLRRNPFEVNCLIAGYDKKDGYQLYWCD 119 Query: 149 PSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIETDDLTI-KLVIKALLEVVQSGGKNIE 207 + A G GA V L+K Y ++ + L I KL + L + N E Sbjct: 120 YLSNMDSVNKGAHGYGAYLVSAILDKYYHENLTVDEALDIFKLCFEELKKRFLLTQINYE 179 Query: 208 LAVMRRDQPLKIL 220 L +M ++ Sbjct: 180 LRIMYDNKVETQY 192 >5FMG-M nrPDB Length = 240 Score = 133 bits (335), Expect = 7e-32, Method: Composition-based stats. Identities = 41/211 (19%), Positives = 83/211 (39%), Gaps = 18/211 (8%) Query: 14 GHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKK-SVAKLQDERTVRKICALDDNVCMA 72 G F+ Y + G T +G+ GKD V+L + + S++ R KI L D + Sbjct: 24 GRGFKRWYPY--IDNGGTVIGLTGKDYVILAADTRLSLSYSIYTRFCPKISKLTDKCIIG 81 Query: 73 FAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISAL 132 +G+ +D + + + + + Q L + I R + + S P+ + Sbjct: 82 SSGMQSDIKTLHSLLQKKIQLFVLEHSHYPDIHVIARLLCVILY----SRRFFPYYAFNI 137 Query: 133 IVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLE----------KNYTDDAIE 182 + G D + LY D G+Y + +G G++ + L+ KN + + Sbjct: 138 LAGVDENNKGVLYNYDSVGSYCEATHSCVGSGSQLILPILDNRVEQKNQLIKNTNFNLGD 197 Query: 183 TDDLTIKLVIKALLEVVQSGGKNIELAVMRR 213 + + A + +G K + + V+ + Sbjct: 198 DINFVKDAITSATERDIYTGDKTL-IYVIDK 227 >3NZW-L nrPDB Length = 241 Score = 131 bits (329), Expect = 3e-31, Method: Composition-based stats. Identities = 49/233 (21%), Positives = 87/233 (37%), Gaps = 36/233 (15%) Query: 20 EYAQEAVK------------KGSTAVGVRGKDIVVLGVEKKSVAKL-QDERTVRKICALD 66 EY+ EA G T +G+ G+D VL + +++ + R K+ Sbjct: 7 EYSSEASNTPIEHQFNPYGDNGGTILGIAGEDFAVLAGDTRNITDYSINSRYEPKVFDCG 66 Query: 67 DNVCMAFAGLTADARIVINRARVECQSHRLTVEDP-VTVEYITRYIASLKQRYTQSNGRR 125 DN+ M+ G AD ++ R + + + D +++ R I Q Sbjct: 67 DNIVMSANGFAADGDALVKRFKNSVKWYHFDHNDKKLSINSAARNI----QHLLYGKRFF 122 Query: 126 PFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIETDD 185 P+ + +I G D DG +Y DP G+Y + A G A + FL+ Sbjct: 123 PYYVHTIIAGLDEDGKGAVYSFDPVGSYEREQCRAGGAAASLIMPFLDNQVNFKNQYEPG 182 Query: 186 -----------LTIKLVIKALLEVVQSG-------GKNIELAVMRRDQPLKIL 220 L+++ VIK + + S G +E+ ++ +D K Sbjct: 183 TNGKVKKPLKYLSVEEVIKLVRDSFTSATERHIQVGDGLEILIVTKDGVRKEF 235 >5FMG-L nrPDB Length = 211 Score = 128 bits (323), Expect = 2e-30, Method: Composition-based stats. Identities = 35/199 (17%), Positives = 80/199 (40%), Gaps = 9/199 (4%) Query: 30 STAVGVRGKDIVVLGVEKK-SVAKLQDERTVRKICALDDNVCMAFAGLTADARIVINRAR 88 +T + + KD +++ V+ + S+ + V KI ++ N+ AG AD Sbjct: 1 TTTLAFKFKDGIIVAVDSRASMGSFISSQNVEKIIEINKNILGTMAGGAADCLYWEKYLG 60 Query: 89 VECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQTD 148 + + L + ++V + ++++ +Y ++ G+D G ++ D Sbjct: 61 KIIKIYELRNNEKISVRAASTILSNILYQYKGYG----LCCGIILSGYDHTG-FNMFYVD 115 Query: 149 PSGTYHAWKANAIGRGAKSVREFLEK--NYTDDAIETDDLTIKLVIKALLEVVQSGGKNI 206 SG + G G+ L+ +Y + + +L + A SGGK + Sbjct: 116 DSGKKVEGNLFSCGSGSTYAYSILDSAYDYNLNLDQAVELARNAIYHATFRDGGSGGK-V 174 Query: 207 ELAVMRRDQPLKILNPEEI 225 + + ++ KI+ E++ Sbjct: 175 RVFHIHKNGYDKIIEGEDV 193 >6EPC-1 nrPDB Length = 238 Score = 113 bits (282), Expect = 9e-26, Method: Composition-based stats. Identities = 36/192 (18%), Positives = 71/192 (36%), Gaps = 7/192 (3%) Query: 26 VKKGSTAVGVRGKDIVVLGVEKKSV-AKLQDERTVRKICALDDNVCMAFAGLTADARIVI 84 V G+T + V+ VVLG + ++ R K+ + D++ +G AD + V Sbjct: 30 VSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDHIFCCRSGSAADTQAVA 89 Query: 85 NRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRL 144 + + H + + +P V + RY R +I G+D ++ Sbjct: 90 DAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRY-----REDLMAGIIIAGWDPQEGGQV 144 Query: 145 YQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIETDDLTIKL-VIKALLEVVQSGG 203 Y G G G+ + +++ Y + + + L + +E S G Sbjct: 145 YSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKDECLQFTANALALAMERDGSSG 204 Query: 204 KNIELAVMRRDQ 215 I LA +++ Sbjct: 205 GVIRLAAIQQSG 216 >5GJQ-a nrPDB Length = 239 Score = 111 bits (277), Expect = 3e-25, Method: Composition-based stats. Identities = 39/209 (18%), Positives = 76/209 (36%), Gaps = 8/209 (3%) Query: 26 VKKGSTAVGVRGKDIVVLGVEKKSV-AKLQDERTVRKICALDDNVCMAFAGLTADARIVI 84 V G+T + V+ VVLG + ++ R K+ + D + +G AD + V Sbjct: 31 VSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVA 90 Query: 85 NRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRL 144 + + H + + +P V + RY R +I G+D ++ Sbjct: 91 DAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRY-----REDLMAGIIIAGWDPQEGGQV 145 Query: 145 YQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIETDDLTIKL-VIKALLEVVQSGG 203 Y G G G+ + +++ Y + + + L + +E S G Sbjct: 146 YSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSG 205 Query: 204 KNIELAVMRRDQ-PLKILNPEEIEKYVAE 231 I LA + ++L ++I K+ Sbjct: 206 GVIRLAAIAESGVERQVLLGDQIPKFAVA 234 >5L4G-U nrPDB Length = 241 Score = 110 bits (276), Expect = 4e-25, Method: Composition-based stats. Identities = 31/199 (15%), Positives = 71/199 (35%), Gaps = 15/199 (7%) Query: 28 KGSTAVGVRGKDIVVLGVEKK-SVAKLQDERTVRKICALDDNVCMAFAGLTADARIVINR 86 G T + + G+D ++ + + S R K L D + +G D + Sbjct: 36 NGGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKI 95 Query: 87 ARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQ 146 + ++ + +T I ++++ S P+ + +I G D +G +Y Sbjct: 96 IEARLKMYKHSNNKAMTTGAIAAMLSTILY----SRRFFPYYVYNIIGGLDEEGKGAVYS 151 Query: 147 TDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIETDD----------LTIKLVIKALL 196 DP G+Y A G + ++ L+ ++ + +K V + Sbjct: 152 FDPVGSYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLSLDRAMRLVKDVFISAA 211 Query: 197 EVVQSGGKNIELAVMRRDQ 215 E G + + ++ ++ Sbjct: 212 ERDVYTGDALRICIVTKEG 230 >5VFT-S nrPDB Length = 213 Score = 109 bits (273), Expect = 1e-24, Method: Composition-based stats. Identities = 31/199 (15%), Positives = 71/199 (35%), Gaps = 15/199 (7%) Query: 28 KGSTAVGVRGKDIVVLGVEKK-SVAKLQDERTVRKICALDDNVCMAFAGLTADARIVINR 86 G T + + G+D ++ + + S R K L D + +G D + Sbjct: 8 NGGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKI 67 Query: 87 ARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQ 146 + ++ + +T I ++++ S P+ + +I G D +G +Y Sbjct: 68 IEARLKMYKHSNNKAMTTGAIAAMLSTILY----SRRFFPYYVYNIIGGLDEEGKGAVYS 123 Query: 147 TDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIETDD----------LTIKLVIKALL 196 DP G+Y A G + ++ L+ ++ + +K V + Sbjct: 124 FDPVGSYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLSLDRAMRLVKDVFISAA 183 Query: 197 EVVQSGGKNIELAVMRRDQ 215 E G + + ++ ++ Sbjct: 184 ERDVYTGDALRICIVTKEG 202 >6EPF-6 nrPDB Length = 240 Score = 108 bits (270), Expect = 2e-24, Method: Composition-based stats. Identities = 37/217 (17%), Positives = 80/217 (36%), Gaps = 27/217 (12%) Query: 10 FSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKK-SVAKLQDERTVRKICALDDN 68 FSP YA G T + + G+D ++ + + S R K L D Sbjct: 29 FSP--------YAF----NGGTVLAIAGEDFSIVASDTRLSEGFSIHTRDSPKCYKLTDK 76 Query: 69 VCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFG 128 + +G D + + ++ + +T I ++++ S P+ Sbjct: 77 TVIGCSGFHGDCLTLTKIIEARLKMYKHSNNKAMTTGAIAAMLSTILY----SRRFFPYY 132 Query: 129 ISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIETDD--- 185 + +I G D +G +Y DP G+Y A G + ++ L+ ++ + Sbjct: 133 VYNIIEGLDEEGKGAVYSFDPVGSYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVP 192 Query: 186 LTIKLVIKALLEVVQS-------GGKNIELAVMRRDQ 215 LT+ ++ + +V S G + + ++ ++ Sbjct: 193 LTLDRAMRLVKDVFISAAERDVYTGDALRICIVTKEG 229 >5MPC-h nrPDB Length = 215 Score = 106 bits (266), Expect = 7e-24, Method: Composition-based stats. Identities = 36/206 (17%), Positives = 78/206 (37%), Gaps = 9/206 (4%) Query: 26 VKKGSTAVGVRGKDIVVLGVEKKSV-AKLQDERTVRKICALDDNVCMAFAGLTADARIVI 84 V G++ + V KD V+LG + ++ R K+ + D + +G AD + + Sbjct: 16 VSLGTSIMAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDKIWCCRSGSAADTQAIA 75 Query: 85 NRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRL 144 + + + + P + E L + ++ G+D + Sbjct: 76 DIVQYHLELYTSQYGTP-STETAASVFKELCYENKDN-----LTAGIIVAGYDDKNKGEV 129 Query: 145 YQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIETDDLT-IKLVIKALLEVVQSGG 203 Y G+ H G G+ + + +KN+ ++ + + + IK + ++ S G Sbjct: 130 YTIPLGGSVHKLPYAIAGSGSTFIYGYCDKNFRENMSKEETVDFIKHSLSQAIKWDGSSG 189 Query: 204 KNIELAVMRRDQPLK-ILNPEEIEKY 228 I + V+ + I P+E E+ Sbjct: 190 GVIRMVVLTAAGVERLIFYPDEYEQL 215 >5LEZ-N nrPDB Length = 205 Score = 105 bits (261), Expect = 3e-23, Method: Composition-based stats. Identities = 37/205 (18%), Positives = 74/205 (36%), Gaps = 8/205 (3%) Query: 30 STAVGVRGKDIVVLGVEKKSV-AKLQDERTVRKICALDDNVCMAFAGLTADARIVINRAR 88 +T + V+ VVLG + ++ R K+ + D + +G AD + V + Sbjct: 1 TTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVADAVT 60 Query: 89 VECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQTD 148 + H + + +P V + RY R +I G+D ++Y Sbjct: 61 YQLGFHSIELNEPPLVHTAASLFKEMCYRY-----REDLMAGIIIAGWDPQEGGQVYSVP 115 Query: 149 PSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIETDDLTIKL-VIKALLEVVQSGGKNIE 207 G G G+ + +++ Y + + + L + +E S G I Sbjct: 116 MGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSGGVIR 175 Query: 208 LAVMRRDQ-PLKILNPEEIEKYVAE 231 LA + ++L ++I K+ Sbjct: 176 LAAIAESGVERQVLLGDQIPKFAVA 200 >5LF3-J nrPDB Length = 201 Score = 101 bits (251), Expect = 4e-22, Method: Composition-based stats. Identities = 27/189 (14%), Positives = 67/189 (35%), Gaps = 12/189 (6%) Query: 33 VGVRGKDIVVLGVEKKSVAKLQ-DERTVRKICALDDNVCMAFAGLTADARIVINRARVEC 91 +G++G D V++ ++ + + + + K+ + + + + G D + Sbjct: 5 IGIQGPDYVLVASDRVAASNIVQMKDDHDKMFKMSEKILLLCVGEAGDTVQFAEYIQKNV 64 Query: 92 QSHRLTVEDPVTVEYIT----RYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQT 147 Q +++ ++ R +A R P+ ++ L+ G+D P LY Sbjct: 65 QLYKMRNGYELSPTAAANFTRRNLADCL------RSRTPYHVNLLLAGYDEHEGPALYYM 118 Query: 148 DPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIETDD-LTIKLVIKALLEVVQSGGKNI 206 D A G GA L++ YT ++ ++ L + Sbjct: 119 DYLAALAKAPFAAHGYGAFLTLSILDRYYTPTISRERAVELLRKCLEELQKRFILNLPTF 178 Query: 207 ELAVMRRDQ 215 + ++ ++ Sbjct: 179 SVRIIDKNG 187 >6AVO-A nrPDB Length = 199 Score = 95.0 bits (235), Expect = 3e-20, Method: Composition-based stats. Identities = 39/203 (19%), Positives = 81/203 (39%), Gaps = 11/203 (5%) Query: 30 STAVGVRGKDIVVLGVEKK-SVAKLQDERTVRKICALDDNVCMAFAGLTADARIVINRAR 88 +T + V VV+G + + S + R K+ L + + A +G ADA+ V + A Sbjct: 1 TTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAVADMAA 60 Query: 89 VECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQTD 148 + + H + +E+P V + ++ +Y R ++ G+D ++Y T Sbjct: 61 YQLELHGIELEEPPLVLAAANVVRNISYKY-----REDLSAHLMVAGWDQREGGQVYGT- 114 Query: 149 PSGTYHAWKANAI-GRGAKSVREFLEKNYTDDAIETD--DLTIKLVIKALLEVVQSGGKN 205 G + AI G G+ + +++ Y + T + A+ SGG Sbjct: 115 -LGGMLTRQPFAIGGSGSTFIYGYVDAAYKPGMSPEECRRFTTDAIALAMSRDGSSGGVI 173 Query: 206 IELAVMRRDQPLKILNPEEIEKY 228 + + +++ E+ K+ Sbjct: 174 YLVTITAAGVDHRVILGNELPKF 196 >1Q5R-H nrPDB Length = 294 Score = 93.5 bits (231), Expect = 8e-20, Method: Composition-based stats. Identities = 43/228 (18%), Positives = 84/228 (36%), Gaps = 20/228 (8%) Query: 28 KGSTAVGVRGKDIVVLGVEKKSV-AKLQDERTVRKICALDDNVCMAFAGLTADARIVINR 86 G+T V + K V+L ++++ L R V + D+ AG A ++ Sbjct: 64 HGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEAVYVTDEYSAAGIAGTAGIAIELVRL 123 Query: 87 ARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDG-----T 141 VE + + P+T + +AS+ + + + L+VG+D D Sbjct: 124 FAVELEHYEKIEGVPLTFDGKANRLASMVRGNLG-AAMQGLAVVPLLVGYDLDADDESRA 182 Query: 142 PRLYQTDPSGTYHAWKAN--AIGRGAKSVREFLEKNYTDDAIETDDLTIKLVIKALLEVV 199 R+ D G + +A A+G G+ + L+K Y+ D ++ ++ I++L + Sbjct: 183 GRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPD--SDEETALRAAIESLYDAA 240 Query: 200 QSGGKN---------IELAVMRRDQPLKILNPEEIEKYVAEIEKEKEE 238 AV ++ E + I E+ E Sbjct: 241 DDDSATGGPDLTRGIYPTAVTITQAGAVHVSEETTSELARRIVAERTE 288 >1Q5Q-H nrPDB Length = 235 Score = 89.6 bits (221), Expect = 1e-18, Method: Composition-based stats. Identities = 43/226 (19%), Positives = 84/226 (37%), Gaps = 20/226 (8%) Query: 30 STAVGVRGKDIVVLGVEKKSV-AKLQDERTVRKICALDDNVCMAFAGLTADARIVINRAR 88 +T V + K V+L ++++ L R V K+ D+ AG A ++ Sbjct: 1 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA 60 Query: 89 VECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDG-----TPR 143 VE + + P+T + +AS+ + + + L+VG+D D R Sbjct: 61 VELEHYEKIEGVPLTFDGKANRLASMVRGNLG-AAMQGLAVVPLLVGYDLDADDESRAGR 119 Query: 144 LYQTDPSGTYHAWKAN--AIGRGAKSVREFLEKNYTDDAIETDDLTIKLVIKALLEVVQS 201 + D G + +A A+G G+ + L+K Y+ D ++ ++ I++L + Sbjct: 120 IVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPD--SDEETALRAAIESLYDAADD 177 Query: 202 GGKN---------IELAVMRRDQPLKILNPEEIEKYVAEIEKEKEE 238 AV ++ E + I E+ E Sbjct: 178 DSATGGPDLTRGIYPTAVTITQAGAVHVSEETTSELARRIVAERTE 223 >3UNF-N nrPDB Length = 199 Score = 85.0 bits (209), Expect = 3e-17, Method: Composition-based stats. Identities = 37/202 (18%), Positives = 77/202 (38%), Gaps = 9/202 (4%) Query: 30 STAVGVRGKDIVVLGVEKK-SVAKLQDERTVRKICALDDNVCMAFAGLTADARIVINRAR 88 +T + V VV+G + + S R K+ L + A +G ADA+ + + A Sbjct: 1 TTIMAVEFDGGVVVGSDSRVSAGTAVVNRVFDKLSPLHQRIFCALSGSAADAQAIADMAA 60 Query: 89 VECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQTD 148 + + H L +E+P V + ++ +Y R ++ G+D ++Y T Sbjct: 61 YQLELHGLELEEPPLVLAAANVVKNISYKY-----REDLLAHLIVAGWDQREGGQVYGTM 115 Query: 149 PSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIETD--DLTIKLVIKALLEVVQSGGKNI 206 G G G+ + +++ Y + T + A+ SGG Sbjct: 116 -GGMLIRQPFTIGGSGSSYIYGYVDAAYKPGMTPEECRRFTTNAITLAMNRDGSSGGVIY 174 Query: 207 ELAVMRRDQPLKILNPEEIEKY 228 + + +++ +E+ K+ Sbjct: 175 LVTITAAGVDHRVILGDELPKF 196 >3UNE-I nrPDB Length = 205 Score = 78.1 bits (191), Expect = 4e-15, Method: Composition-based stats. Identities = 32/193 (16%), Positives = 69/193 (35%), Gaps = 10/193 (5%) Query: 28 KGSTAVGVRGKDIVVLGVEKK--SVAKLQDERTVRKICALDDNVCMAFAGLTADARIVIN 85 G + ++GK+ V + +++ A++ +KI + D + + AGL D + V Sbjct: 7 NGGAVMAMKGKNCVAIAADRRFGIQAQMVTTDF-QKIFPMGDRLYIGLAGLATDVQTVAQ 65 Query: 86 RARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDG-TPRL 144 R + + L + + +A+L P+ +I G D P + Sbjct: 66 RLKFRLNLYELKEGRQIKPYTLMSMVANLLYE----KRFGPYYTEPVIAGLDPKTFKPFI 121 Query: 145 YQTDPSGT-YHAWKANAIGRGAKSVREFLEKNYTDDA-IETDDLTIKLVIKALLEVVQSG 202 D G G ++ + E + + E TI + ++ Sbjct: 122 CSLDLIGCPMVTDDFVVSGTCSEQMYGMCESLWEPNMDPEHLFETISQAMLNAVDRDAVS 181 Query: 203 GKNIELAVMRRDQ 215 G + + V+ +D+ Sbjct: 182 GMGVIVHVIEKDK 194 >4Y8P-I nrPDB Length = 205 Score = 77.3 bits (189), Expect = 6e-15, Method: Composition-based stats. Identities = 35/197 (17%), Positives = 68/197 (34%), Gaps = 9/197 (4%) Query: 28 KGSTAVGVRGKDIVVLGVEKKSVA-KLQDERTVRKICALDDNVCMAFAGLTADARIVINR 86 G V + GKD V + + + + L KI +V + GL D + Sbjct: 8 NGGIVVAMTGKDCVAIACDLRLGSQSLGVSNKFEKIFHYG-HVFLGITGLATDVTTLNEM 66 Query: 87 ARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFD-FDGTPRLY 145 R + ++L E + E T+ ++S P+ + ++ G + G P + Sbjct: 67 FRYKTNLYKLKEERAIEPETFTQLVSSSLYE----RRFGPYFVGPVVAGINSKSGKPFIA 122 Query: 146 QTDPSGTYHAWK-ANAIGRGAKSVREFLEKNYTDDAI-ETDDLTIKLVIKALLEVVQSGG 203 D G K G + + E Y + E TI + + G Sbjct: 123 GFDLIGCIDEAKDFIVSGTASDQLFGMCESLYEPNLEPEDLFETISQALLNAADRDALSG 182 Query: 204 KNIELAVMRRDQPLKIL 220 + ++++D+ +K Sbjct: 183 WGAVVYIIKKDEVVKRY 199 >2JAY-A nrPDB Length = 291 Score = 76.1 bits (186), Expect = 1e-14, Method: Composition-based stats. Identities = 36/183 (19%), Positives = 66/183 (36%), Gaps = 9/183 (4%) Query: 28 KGSTAVGVRGKDIVVLGVEKKSV-AKLQDERTVRKICALDDNVCMAFAGLTADARIVINR 86 G+T V ++ VV+ +++S + R VRK+ DD AG A A Sbjct: 56 HGTTIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARL 115 Query: 87 ARVECQSHRLTVEDPVTVEYITRYIASLKQRYT----QSNGRRPFGISALIVGFDFDGTP 142 VE + + P+T +A + + Q P I D Sbjct: 116 YAVELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAG 175 Query: 143 RLYQTDPSG--TYHAWKANAIGRGAKSVREFLEKNYTDDAIETDDLTIKLVIKALLEVVQ 200 R+ D +G A+G G+ + ++K Y+ + D +++ ++AL + Sbjct: 176 RIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYS--QVTDGDSGLRVAVEALYDAAD 233 Query: 201 SGG 203 Sbjct: 234 DDS 236 >5FMG-J nrPDB Length = 218 Score = 75.4 bits (184), Expect = 2e-14, Method: Composition-based stats. Identities = 39/207 (18%), Positives = 80/207 (38%), Gaps = 20/207 (9%) Query: 28 KGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVR--KICALDDNVCMAFAGLTADARIVIN 85 G +G+ G + V + + + A + + KI +++NV + +GL D + + Sbjct: 8 NGGCVLGMSGSNCVAIACDLRLGANTFTTVSTKFSKIFKMNNNVYVGLSGLATDIQTLYE 67 Query: 86 RARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVG------FDFD 139 R + + + + VE ++S+ SN P+ ++ ++VG D + Sbjct: 68 ILRYRVNLYEVRQDAEMDVECFANMLSSILY----SNRFSPYFVNPIVVGFKLKHYVDEE 123 Query: 140 G------TPRLYQTDPSGTYHAWKANAI-GRGAKSVREFLEKNYTDDAIET-DDLTIKLV 191 G P L D G + + G ++ + E Y D E TI Sbjct: 124 GEKKVNYEPYLTAYDLIGAKCETRDFVVNGVTSEQLFGMCESLYVKDQDENGLFETISQC 183 Query: 192 IKALLEVVQSGGKNIELAVMRRDQPLK 218 + + L+ G E+ V+ ++ +K Sbjct: 184 LLSALDRDCISGWGAEVLVLTPEKIIK 210 >5FMG-N nrPDB Length = 265 Score = 74.6 bits (182), Expect = 4e-14, Method: Composition-based stats. Identities = 34/230 (14%), Positives = 76/230 (33%), Gaps = 42/230 (18%) Query: 26 VKKGSTAVGVRGKDIVVLGVEKKSV-AKLQDERTVRKICALDDNVCMAFAGLTADARIVI 84 V G++ + ++ K +++ ++K+ + V +I +++ M F+G ADA+ + Sbjct: 6 VVTGTSVIAIKYKHGIMIAADRKASYGSYAKFQNVERIFKINNKTVMGFSGELADAQYLH 65 Query: 85 NRA-RVEC-QSHRLTVEDPV-TVEYITRYIASLKQRYTQSNGRRPFGISALIVG-----F 136 R ++ + T ++ Y++ + Y + N P + +I G + Sbjct: 66 ELLTRKNINNLSEKKRKEDMYTPQHYHSYVSRVF--YVRKNRIDPLFNNIIIAGINSQKY 123 Query: 137 DFDGTPRLYQT------------------------------DPSGTYHAWKANAIGRGAK 166 D + L T D GT G Sbjct: 124 DNNDDNVLLYTNKNNDDEQNEYKNNEEYKEIHKDDLYIGFVDMHGTNFCDDYITTGYARY 183 Query: 167 SVREFLEKNYTDDAIETDD-LTIKLVIKALLEVVQSGGKNIELAVMRRDQ 215 L +Y D+ E + + I ++ L + I++ + Sbjct: 184 FALTLLRDHYKDNMTEEEARILINECLRILYFRDATSSNFIQIVKVTSKG 233 >6GOP-M nrPDB Length = 246 Score = 73.8 bits (180), Expect = 6e-14, Method: Composition-based stats. Identities = 33/222 (14%), Positives = 83/222 (37%), Gaps = 14/222 (6%) Query: 26 VKKGSTAVGVRGKDIVVLGVEKK-SVAKLQDERTVRKICALDDNVCMAFAGLTADARIVI 84 + G++ + ++ + V++ + S L V ++ + DN + +G +D + + Sbjct: 18 IVTGTSVISMKYDNGVIIAADNLGSYGSLLRFNGVERLIPVGDNTVVGISGDISDMQHIE 77 Query: 85 NRARVECQSHRLTV-----EDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFD 139 + + E+ + YI Y+A++ + + + P + ++ G + Sbjct: 78 RLLKDLVTENAYDNPLADAEEALEPSYIFEYLATVMYQ--RRSKMNPLWNAIIVAGVQSN 135 Query: 140 GTPRLYQTDPSGTYHAWKANAIGRGAKSVREFL------EKNYTDDAIETDDLTIKLVIK 193 G L + G ++ A G GA L E + ++ + I ++ Sbjct: 136 GDQFLRYVNLLGVTYSSPTLATGFGAHMANPLLRKVVDRESDIPKTTVQVAEEAIVNAMR 195 Query: 194 ALLEVVQSGGKNIELAVMRRDQPLKILNPEEIEKYVAEIEKE 235 L +N LA++ ++ L ++E + K+ Sbjct: 196 VLYYRDARSSRNFSLAIIDKNTGLTFKKNLQVENMKWDFAKD 237 >5FMG-H nrPDB Length = 252 Score = 68.8 bits (167), Expect = 2e-12, Method: Composition-based stats. Identities = 32/236 (13%), Positives = 84/236 (35%), Gaps = 53/236 (22%) Query: 30 STAVGVRGKDIVVLGVEKK-SVAKLQDERTVRKICALDDNVCMAFAGLTADARIVINRAR 88 +T +G+ + V+L + + S + RKI +++N+ + +G +A ++ +I + Sbjct: 1 TTIIGIIYDNGVMLACDSRTSSGTFISNKCSRKINRINENLYVCRSGASAHSQKIIEIIK 60 Query: 89 VECQSHRL------------------TVEDPVTVEY------------------------ 106 C S + T ++ + ++ Sbjct: 61 HYCVSMKNENRKKGRFHEGETIYDETTYDEEIDIDSINYLDYNNNNDNNLVTKNKYFYED 120 Query: 107 -------ITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKAN 159 + +A + ++ +N + + G+D +LY + +G+ Sbjct: 121 KFNDYNPLVENVAHITKKIIYTNNNF-LSCALIFGGYDKIKKQQLYAVNLNGSIIEKHDF 179 Query: 160 AI-GRGAKSVREFLEKNYTDDAIETDDLTIKL-VIKALLEVVQSGGKNIELAVMRR 213 A+ G G+ ++ +L+ Y + + + L +K + S G I + + + Sbjct: 180 AVSGSGSIYIQSYLQDKYKKFMTKKECFNLILNCVKYAMHNDNSSGGLIRIVNITK 235 >5LZP-A nrPDB Length = 242 Score = 68.8 bits (167), Expect = 2e-12, Method: Composition-based stats. Identities = 35/181 (19%), Positives = 65/181 (35%), Gaps = 9/181 (4%) Query: 30 STAVGVRGKDIVVLGVEKKSV-AKLQDERTVRKICALDDNVCMAFAGLTADARIVINRAR 88 +T V ++ VV+ +++S + R VRK+ DD AG A A Sbjct: 1 ATIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYA 60 Query: 89 VECQSHRLTVEDPVTVEYITRYIASLKQRYT----QSNGRRPFGISALIVGFDFDGTPRL 144 VE + + P+T +A + + Q P I D R+ Sbjct: 61 VELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAGRI 120 Query: 145 YQTDPSG--TYHAWKANAIGRGAKSVREFLEKNYTDDAIETDDLTIKLVIKALLEVVQSG 202 D +G A+G G+ + ++K Y+ + D +++ ++AL + Sbjct: 121 VSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYS--QVTDGDSGLRVAVEALYDAADDD 178 Query: 203 G 203 Sbjct: 179 S 179 >5GJQ-g nrPDB Length = 264 Score = 64.6 bits (156), Expect = 4e-11, Method: Composition-based stats. Identities = 42/221 (19%), Positives = 83/221 (37%), Gaps = 23/221 (10%) Query: 28 KGSTAVGVRGKDIVVLGVEKK-SVAKLQDERTVRKICALDDNVCMAFAGLTADARIVINR 86 G++ +GV+ + VV+ + S L R + +I ++++ + +G AD + + Sbjct: 52 TGTSVLGVKFEGGVVIAADMLGSYGSLARFRNISRIMRVNNSTMLGASGDYADFQYLKQV 111 Query: 87 ARVECQSHRLTVE----DPVTVEY-ITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGT 141 L + P + +TR + Y++ + P + +I G+ DG Sbjct: 112 LGQMVIDEELLGDGHSYSPRAIHSWLTRAM------YSRRSKMNPLWNTMVIGGY-ADGE 164 Query: 142 PRLYQTDPSGTYHAWKANAIGRGAKSVR----EFLEKNYTDDAIETDDLTIKLVIKALLE 197 L D G + + A G GA + E LEK E DL ++ ++ L Sbjct: 165 SFLGYVDMLGVAYEAPSLATGYGAYLAQPLLREVLEKQPVLSQTEARDL-VERCMRVLYY 223 Query: 198 VVQSGGKNIELAVMRR-----DQPLKILNPEEIEKYVAEIE 233 ++A + + PL +I ++ E Sbjct: 224 RDARSYNRFQIATVTEKGVEIEGPLSTETNWDIAHMISGFE 264 >5LF6-M nrPDB Length = 219 Score = 63.0 bits (152), Expect = 1e-10, Method: Composition-based stats. Identities = 42/221 (19%), Positives = 83/221 (37%), Gaps = 23/221 (10%) Query: 28 KGSTAVGVRGKDIVVLGVEKK-SVAKLQDERTVRKICALDDNVCMAFAGLTADARIVINR 86 G++ +GV+ + VV+ + S L R + +I ++++ + +G AD + + Sbjct: 7 TGTSVLGVKFEGGVVIAADMLGSYGSLARFRNISRIMRVNNSTMLGASGDYADFQYLKQV 66 Query: 87 ARVECQSHRLTVE----DPVTVEY-ITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGT 141 L + P + +TR + Y++ + P + +I G+ DG Sbjct: 67 LGQMVIDEELLGDGHSYSPRAIHSWLTRAM------YSRRSKMNPLWNTMVIGGY-ADGE 119 Query: 142 PRLYQTDPSGTYHAWKANAIGRGAKSVR----EFLEKNYTDDAIETDDLTIKLVIKALLE 197 L D G + + A G GA + E LEK E DL ++ ++ L Sbjct: 120 SFLGYVDMLGVAYEAPSLATGYGAYLAQPLLREVLEKQPVLSQTEARDL-VERCMRVLYY 178 Query: 198 VVQSGGKNIELAVMRR-----DQPLKILNPEEIEKYVAEIE 233 ++A + + PL +I ++ E Sbjct: 179 RDARSYNRFQIATVTEKGVEIEGPLSTETNWDIAHMISGFE 219 >6EPE-7 nrPDB Length = 263 Score = 59.6 bits (143), Expect = 1e-09, Method: Composition-based stats. Identities = 41/221 (18%), Positives = 81/221 (36%), Gaps = 23/221 (10%) Query: 28 KGSTAVGVRGKDIVVLGVEKK-SVAKLQDERTVRKICALDDNVCMAFAGLTADARIVINR 86 G++ +GV+ VV+ + S L R + +I ++D+ + +G AD + + Sbjct: 51 TGTSVLGVKFDCGVVIAADMLGSYGSLARFRNISRIMRVNDSTMLGASGDYADFQYLKQV 110 Query: 87 ARVECQSHRLTVE----DPVTVEY-ITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGT 141 L + P + +TR + Y++ + P + +I G+ G Sbjct: 111 LGQMVIDEELFGDGHSYSPRAIHSWLTRAM------YSRRSKMNPLWNTKVIGGY-AGGE 163 Query: 142 PRLYQTDPSGTYHAWKANAIGRGAKSVR----EFLEKNYTDDAIETDDLTIKLVIKALLE 197 L D G + + A G GA + E LEK E +L ++ ++ L Sbjct: 164 SFLGYVDMLGVAYEAPSLATGYGAYLAQPLLREVLEKQPVLSQTEAREL-VERCMRVLYY 222 Query: 198 VVQSGGKNIELAVMRR-----DQPLKILNPEEIEKYVAEIE 233 ++A + + PL +I ++ E Sbjct: 223 RDARSYNRFQVATVTEKGVEIEGPLSAQTNWDIAHMISGFE 263 >4HO7-A nrPDB Length = 179 Score = 51.5 bits (122), Expect = 3e-07, Method: Composition-based stats. Identities = 29/146 (19%), Positives = 56/146 (38%), Gaps = 19/146 (13%) Query: 30 STAVGVRGKDIVVLGVEKKSV--AKLQDERTVRKICALDDNVCMAFAGLTADARIVINRA 87 +T + VR D VVL +++ ++ + + K+ ++D+V + FAG TADA ++ + Sbjct: 1 TTILSVRKGDTVVLLGDRQVTLGERIVAKSSACKLRRINDDVVIGFAGSTADAISLMEKL 60 Query: 88 RVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQT 147 + +TR L + + R S ++ + + Sbjct: 61 ENKIGEF---------PNQLTRAAVELAKEWRTDRALRRLEASLIVCSAEET-----LEI 106 Query: 148 DPSGTYHAWKA---NAIGRGAKSVRE 170 D G +A AIG G + Sbjct: 107 DGQGNVITPEADGIVAIGSGGTFAKA 132 >5LOX-A nrPDB Length = 242 Score = 48.4 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 43/222 (19%), Positives = 82/222 (36%), Gaps = 17/222 (7%) Query: 30 STAVGVRGKDIVVLGVEKKSVAKLQDERTVRKICALD----DNVCMAFAGLTADARIVIN 85 + V + D +V + ++ A + T RK+ + + AG A ++ VIN Sbjct: 1 TYCVAMHLADGLVFASDSRTNAGIDHIATFRKLFTFGTPGERLLVVQTAGNLATSQSVIN 60 Query: 86 RARVECQSHRLTVEDPVTVEYITRYIAS-----LKQRYTQSNGRRPFGISALIVGFDFDG 140 + + ++ + +V T +A + + G S ++ G G Sbjct: 61 LLQQRIRRDGASLLNVPSVYDATALVAETTREVMARDSGNLAGNTDLSCSFMVGGQIAGG 120 Query: 141 TPRLYQTDPSGTYHAW----KANAIGRGAKSVREFLEKNYTDDAIETDDLTIKLV-IKAL 195 P LY P G + +G +K + L++N T D L LV + Sbjct: 121 PPALYSIYPQGNFIQATPDTPFLQLGE-SKYGKPILDRNLTFDTPLEQALRCALVSFDST 179 Query: 196 LEVVQSGGKNIELAVMRRDQPL--KILNPEEIEKYVAEIEKE 235 + S G ++L V RD + + E + Y + I ++ Sbjct: 180 IRSNLSVGMPLDLLVYHRDSLILPEGYRVTEDDAYFSAIRRQ 221 >5LOY-A nrPDB Length = 240 Score = 46.5 bits (109), Expect = 1e-05, Method: Composition-based stats. Identities = 41/226 (18%), Positives = 78/226 (34%), Gaps = 18/226 (7%) Query: 30 STAVGVRGKDIVVLGVEKKSVAKLQDERTVRKICALD----DNVCMAFAGLTADARIVIN 85 + VG+R + +V + ++ A + + T RK+ + + + AG A + VI+ Sbjct: 1 TYCVGIRLDEGLVFASDSRTNAGVDNISTFRKMHVFEVPGERVIVLLTAGNLATTQAVIS 60 Query: 86 RARVECQSHRLTVEDPVTVEYITRYIASLKQR------YTQSNGRRPFGISALIVGFDFD 139 + + ++ R + + F S ++ G Sbjct: 61 LLEERLKDPEERLLTAPSMFEAARLVGEALREVQARDAPALEADGVDFNASFILGGQIAG 120 Query: 140 GTPRLYQTDPSGTYHAW----KANAIGRGAKSVREFLEKNYTDDAIETDDLTIKLV-IKA 194 PRL+ P+G + IG K + L++ T D D LV + Sbjct: 121 EPPRLFLIYPAGNFIEATPDTPFFQIGE-TKYGKPILDRVITPDTSLEDAAKCALVSFDS 179 Query: 195 LLEVVQSGGKNIELAVMRRDQPL--KILNPEEIEKYVAEIEKEKEE 238 + S G ++L V RD +E + Y + K+ E Sbjct: 180 TMRSNLSVGLPLDLLVYERDSLRVGHRRRIDEDDPYFRMLRKQWSE 225 >5NYF-A nrPDB Length = 245 Score = 44.2 bits (103), Expect = 5e-05, Method: Composition-based stats. Identities = 33/220 (15%), Positives = 67/220 (30%), Gaps = 27/220 (12%) Query: 29 GSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRKICAL----DDNVCMAFAGLTADARIVI 84 G+ AV R + +V + ++ A + + +K+ + + AG A + V+ Sbjct: 2 GTYAVAFRLERGLVFAADTRTNAGVDNIAQYKKLQLWRQPGERVFVLLSAGNLAATQAVV 61 Query: 85 NRARVECQSHRLTVEDP-------VTVEYITRYIASLKQRY------TQSNGRRPFGISA 131 + +D + R + + + F + Sbjct: 62 SLINEHLSQ---ETDDEVTTLFTAPNMYRAARVVGDAVREARSIDGAALEASKLGFNTNF 118 Query: 132 LIVGFDFDGTPRLYQTDPSGTYHAW----KANAIGRGAKSVREFLEKNYTDDA-IETDDL 186 + G PRL+Q P G + IG + L++ D + Sbjct: 119 IFGGQIKGERPRLFQIYPEGNFIEATDDTPFFQIGEHKYG-KPILDRVARSDMRLGEAAK 177 Query: 187 TIKLVIKALLEVVQSGGKNIELAVMRRDQPLKILNPEEIE 226 + L + L S G I+L V+ + + I Sbjct: 178 LMLLSFDSTLRSNLSVGMPIDL-VIYERDTFDVTREKRIS 216 >5JI2-A nrPDB Length = 184 Score = 42.2 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 19/68 (27%), Positives = 32/68 (47%), Gaps = 2/68 (2%) Query: 30 STAVGVRGKDIVVLGVEKKSV-AKLQDERTVRKICAL-DDNVCMAFAGLTADARIVINRA 87 +T V VR VV+ + ++ + V+K+ L +D V FAG TADA + Sbjct: 2 TTIVSVRRNGHVVIAGDGQATLGNTVMKGNVKKVRRLYNDKVIAGFAGGTADAFTLFELF 61 Query: 88 RVECQSHR 95 + + H+ Sbjct: 62 ERKLEMHQ 69 >5NYW-A nrPDB Length = 251 Score = 40.3 bits (93), Expect = 8e-04, Method: Composition-based stats. Identities = 26/178 (14%), Positives = 59/178 (33%), Gaps = 17/178 (9%) Query: 30 STAVGVRGKDIVVLGVEKKSVAKLQDERTVRKICAL----DDNVCMAFAGLTADARIVIN 85 + V +R + + ++ A + T RK+ + + + AG A + +++ Sbjct: 1 TYCVAMRLSSGLAFASDSRTNAGVDHISTFRKLHLFQQPGERTLVVQSAGNLATTQSIVS 60 Query: 86 RARVECQSHRLTVEDPVT--------VEYITRYIASLKQRYTQSNGRRPFGISALIVGFD 137 + C T V + R + + Q++ F + L+ G Sbjct: 61 LLQRRCLDPEQTNLMNVASMYEAATLLGETVREVINRDSGAQQNSHGTDFNCNLLLGGQI 120 Query: 138 FDGTPRLYQTDPSGTYHAW----KANAIGRGAKSVREFLEKNYTDDAIETDDLTIKLV 191 RL+ P G + IG +K + +++ + D + L+ Sbjct: 121 KGEGLRLFHIYPQGNFIEATQDTPYFQIGE-SKYGKPIIDRVLSYDTPLDQAMQCALI 177 >1OFH-G nrPDB Length = 174 Score = 37.2 bits (85), Expect = 0.007, Method: Composition-based stats. Identities = 32/192 (16%), Positives = 64/192 (33%), Gaps = 25/192 (13%) Query: 30 STAVGVRGKDIVVLGVE-KKSVAKLQDERTVRKICAL-DDNVCMAFAGLTADARIVINRA 87 +T V VR VV+G + + S+ + RK+ L + V FAG TADA + Sbjct: 1 TTIVSVRRNGQVVVGGDGQVSLGNTVMKGNARKVRRLYNGKVLAGFAGGTADAFTLFELF 60 Query: 88 RVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQT 147 + + H+ ++ + L + + R ++ D + + Sbjct: 61 ERKLEMHQ---------GHLLKSAVELAKDWRTDRALRKLEAMLIVA--DEKESLIITGI 109 Query: 148 DPSGTYHAWKANAIGRGAKSVREFLEKNYTDDAIETDDLTIKLVIKALLEVVQSGGKNIE 207 + AIG G +E +L+ +++ L + + Sbjct: 110 GDVVQPEEDQILAIGSGGNYALSA-----ARALVENTELSAHEIVEKSLRIAG------D 158 Query: 208 LAVMRRDQPLKI 219 + V + I Sbjct: 159 ICVFT-NTNFTI 169 >6DTT-A nrPDB Length = 383 Score = 36.8 bits (84), Expect = 0.010, Method: Composition-based stats. Identities = 22/77 (28%), Positives = 30/77 (38%), Gaps = 13/77 (16%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRKI 62 YD A+ FS G L+ V YA EAV + KD V K++ +L K Sbjct: 88 YDTALKAFSYGGKLYGVPYAMEAVAL------IYNKDYV--DSVPKTMDELI-----EKA 134 Query: 63 CALDDNVCMAFAGLTAD 79 +D+ G D Sbjct: 135 KQIDEEYGGEVRGFIYD 151 >1M4Y-A nrPDB Length = 171 Score = 32.6 bits (73), Expect = 0.16, Method: Composition-based stats. Identities = 27/142 (19%), Positives = 48/142 (33%), Gaps = 18/142 (12%) Query: 30 STAVGVRGKDIVVLGVEKKSV-AKLQDERTVRKICALDD-NVCMAFAGLTADARIVINRA 87 +T + VR V+G + + + RK+ L + V FAG ADA + +R Sbjct: 1 TTILVVRRNGQTVMGGDGQVTFGSTVLKGNARKVRKLGEGKVLAGFAGSVADAMTLFDRF 60 Query: 88 RVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQT 147 + + +T+ L + + R L+ D + ++ Sbjct: 61 EAKLREWGGN---------LTKAAVELAKDWRTDRVLRRLEALLLVA--DKEN---IFII 106 Query: 148 DPSGTYHA--WKANAIGRGAKS 167 +G A AIG G Sbjct: 107 SGNGEVIQPDDDAAAIGSGGPY 128 >2GHB-A nrPDB Length = 382 Score = 31.5 bits (70), Expect = 0.36, Method: Composition-based stats. Identities = 10/25 (40%), Positives = 15/25 (60%) Query: 3 YDRAITVFSPDGHLFQVEYAQEAVK 27 Y+ A+ FS G L+ + YA EA+ Sbjct: 88 YETALNAFSYGGKLYGIPYAMEAIA 112 >4OQJ-A nrPDB Length = 845 Score = 31.1 bits (69), Expect = 0.46, Method: Composition-based stats. Identities = 18/56 (32%), Positives = 25/56 (44%), Gaps = 9/56 (16%) Query: 9 VFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRKICA 64 +FSPDGH A +A +G T +G + V V K+ L D TV + Sbjct: 237 IFSPDGHCR----AFDAKAQG-TVIG----NGVGAVVLKRLSDALADGDTVHAVIK 283 >4W8N-A nrPDB Length = 330 Score = 29.9 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 13/62 (20%), Positives = 23/62 (37%), Gaps = 2/62 (3%) Query: 6 AITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRKICAL 65 + F G+L EY + K+GS+ G+ + ++ E K L T + Sbjct: 241 DVINFESTGNLIAPEYGFKISKRGSS--GIMKTEKILENCETKCQTPLGAINTTLPFHNI 298 Query: 66 DD 67 Sbjct: 299 HP 300 >3QQE-A nrPDB Length = 327 Score = 29.5 bits (65), Expect = 1.2, Method: Composition-based stats. Identities = 13/62 (20%), Positives = 21/62 (33%), Gaps = 2/62 (3%) Query: 6 AITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRKICAL 65 F G+L EY + K+GS+ G+ + + E K L T + Sbjct: 238 DTINFESTGNLIAPEYGFKISKRGSS--GIMKTEGTLENCETKCQTPLGAINTTLPFHNV 295 Query: 66 DD 67 Sbjct: 296 HP 297 >2WR7-A nrPDB Length = 506 Score = 29.5 bits (65), Expect = 1.2, Method: Composition-based stats. Identities = 13/62 (20%), Positives = 21/62 (33%), Gaps = 2/62 (3%) Query: 6 AITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRKICAL 65 F G+L EY + K+GS+ G+ + + E K L T + Sbjct: 251 DTINFESTGNLIAPEYGFKISKRGSS--GIMKTEGTLENCETKCQTPLGAINTTLPFHNV 308 Query: 66 DD 67 Sbjct: 309 HP 310 >2PF1-A nrPDB Length = 156 Score = 29.1 bits (64), Expect = 1.8, Method: Composition-based stats. Identities = 18/99 (18%), Positives = 29/99 (29%), Gaps = 14/99 (14%) Query: 54 QDERTVRKICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIAS 113 K+ + C G+ + + R+ +ECQ R + T A Sbjct: 50 SARNPREKLNECLEGNCAEGVGMNYRGNVSVTRSGIECQLWRSRYPHKPEINSTTHPGAD 109 Query: 114 LKQR--------------YTQSNGRRPFGISALIVGFDF 138 L++ YT S R S + G D Sbjct: 110 LRENFCRNPDGSITGPWCYTTSPTLRREECSVPVCGQDR 148 >1G61-A nrPDB Length = 228 Score = 29.1 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 13/46 (28%), Positives = 20/46 (43%), Gaps = 4/46 (8%) Query: 16 LFQVEYAQEAVKK-GSTAVG---VRGKDIVVLGVEKKSVAKLQDER 57 LF+VEY + G+T+VG + V+G + L E Sbjct: 178 LFKVEYIGKGTANKGTTSVGACIIANSKGAVVGGDTTGPELLIIED 223 >3PFQ-A nrPDB Length = 674 Score = 28.8 bits (63), Expect = 2.3, Method: Composition-based stats. Identities = 11/40 (27%), Positives = 19/40 (47%) Query: 207 ELAVMRRDQPLKILNPEEIEKYVAEIEKEKEENEKKKQKK 246 EL D K+L+ EE E + + E E ++ ++K Sbjct: 266 ELQKAGVDGWFKLLSQEEGEYFNVPVPPEGSEGNEELRQK 305 >2E21-A nrPDB Length = 317 Score = 28.8 bits (63), Expect = 2.3, Method: Composition-based stats. Identities = 10/53 (18%), Positives = 22/53 (41%), Gaps = 1/53 (1%) Query: 46 EKKSVAKLQDERTVRKICALDDNVCMAFAGLTADARIVINRARVECQSHRLTV 98 E + + K+ + KI + + V +AF+G D+ ++ + L Sbjct: 4 ESRVIRKVLALQNDEKIFSGERRVLIAFSGGV-DSVVLTDVLLKLKNYFSLKE 55 >2Z3B-A nrPDB Length = 180 Score = 28.8 bits (63), Expect = 2.5, Method: Composition-based stats. Identities = 14/70 (20%), Positives = 28/70 (40%), Gaps = 3/70 (4%) Query: 28 KGSTAVGVRGKDIVVLGVEKKSV--AKLQDERTVRKICAL-DDNVCMAFAGLTADARIVI 84 +T V+ K + + + + + T RK+ L + V FAG ADA + Sbjct: 4 HATTIFAVQHKGRSAMSGDGQVTFGQAVVMKHTARKVRKLFNGKVLAGFAGSVADAFTLF 63 Query: 85 NRARVECQSH 94 + + + + Sbjct: 64 EKFEAKLEEY 73 >3MYR-A nrPDB Length = 269 Score = 28.4 bits (62), Expect = 2.8, Method: Composition-based stats. Identities = 16/71 (22%), Positives = 23/71 (32%), Gaps = 3/71 (4%) Query: 94 HRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIV-GFDFDGTPRLYQTDPSGT 152 H L ++ R +A Q RRPF L FD +G + + G Sbjct: 160 HYLVFGRLPELDGYGRPLAFYGQSIHDRCYRRPFYDKGLFAESFDDEGAKQGWCLYRLGC 219 Query: 153 Y--HAWKANAI 161 + A A Sbjct: 220 KGPTTYNACAT 230 >2WR0-A nrPDB Length = 509 Score = 28.4 bits (62), Expect = 3.0, Method: Composition-based stats. Identities = 13/62 (20%), Positives = 22/62 (35%), Gaps = 2/62 (3%) Query: 6 AITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKDIVVLGVEKKSVAKLQDERTVRKICAL 65 + F G+L EY + K+GS+ G+ + + E K L T + Sbjct: 251 DVINFESTGNLIAPEYGFKISKRGSS--GIMKTEKTLENCETKCQTPLGAINTTLPFHNI 308 Query: 66 DD 67 Sbjct: 309 HP 310 >1JSO-A nrPDB Length = 325 Score = 28.0 bits (61), Expect = 3.7, Method: Composition-based stats. Identities = 12/61 (19%), Positives = 22/61 (36%), Gaps = 8/61 (13%) Query: 10 FSPDGHLFQVEYAQEAVKKGSTAV---GVRGKDIVVLGVEKKSVAKLQDERTVRKICALD 66 F +G+ EYA + VKKG +A+ G+ + K + + + Sbjct: 241 FESNGNFIAPEYAYKIVKKGGSAIMKSGLEYGNC-----NTKCQTPMGAINSSMPFHNIH 295 Query: 67 D 67 Sbjct: 296 P 296 >3GTD-A nrPDB Length = 482 Score = 28.0 bits (61), Expect = 3.8, Method: Composition-based stats. Identities = 13/35 (37%), Positives = 19/35 (54%), Gaps = 12/35 (34%) Query: 10 FSPDGHLFQVEYAQEAVK----------KGSTAVG 34 FS G++ Q+EYA E ++ +G TAVG Sbjct: 222 FS--GYITQIEYALERIEDALKKVYLLAQGGTAVG 254 >1KSU-A nrPDB Length = 571 Score = 27.6 bits (60), Expect = 5.0, Method: Composition-based stats. Identities = 11/56 (19%), Positives = 24/56 (42%), Gaps = 4/56 (7%) Query: 36 RGKDIVVLGVEKKSVAKLQDERTVRK-ICALDDNVCMAFAGLTADARIVINRARVE 90 R K + + A L + +VRK + +D + + G+ A ++ ++E Sbjct: 402 RDKASAAILAQTGKSAYLIFDDSVRKSLSKIDKYIGL---GVAPTADSLVKLGKME 454 >3TY6-A nrPDB Length = 183 Score = 27.6 bits (60), Expect = 5.9, Method: Composition-based stats. Identities = 13/70 (18%), Positives = 24/70 (34%), Gaps = 3/70 (4%) Query: 28 KGSTAVGVRGKDIVVLGVEKKSV--AKLQDERTVRKICAL-DDNVCMAFAGLTADARIVI 84 +T V + + + + + T RK+ L V FAG ADA + Sbjct: 8 HATTIFAVHHNGECAMAGDGQVTMGNAVVMKHTARKVRKLFQGKVLAGFAGSVADAFTLF 67 Query: 85 NRARVECQSH 94 + + + Sbjct: 68 EMFEGKLEEY 77 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.145 0.376 Lambda K H 0.267 0.0446 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,211,515 Number of Sequences: 36641 Number of extensions: 370134 Number of successful extensions: 1846 Number of sequences better than 10.0: 104 Number of HSP's better than 10.0 without gapping: 127 Number of HSP's successfully gapped in prelim test: 64 Number of HSP's that attempted gapping in prelim test: 1482 Number of HSP's gapped (non-prelim): 214 length of query: 248 length of database: 10,336,785 effective HSP length: 95 effective length of query: 153 effective length of database: 6,855,890 effective search space: 1048951170 effective search space used: 1048951170 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 58 (26.8 bits)