BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9Y6N5 (450 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6MO6-A nrPDB 855 0.0 3HYW-A nrPDB 70 2e-12 3H8L-A nrPDB 62 4e-10 3T14-A nrPDB 59 6e-09 1FCD-A nrPDB 57 2e-08 3VRD-B nrPDB 52 4e-07 5N1T-A nrPDB 51 1e-06 5NA1-A nrPDB 40 0.002 4G74-A nrPDB 39 0.004 5JWC-A nrPDB 37 0.015 3F8P-A nrPDB 37 0.015 5MJK-A nrPDB 36 0.042 5I68-A nrPDB 33 0.31 1ZDL-A nrPDB 31 0.89 2DWU-A nrPDB 30 2.1 3VML-A nrPDB 30 2.1 3VMK-A nrPDB 30 2.2 3V7P-A nrPDB 30 2.9 4Y1B-A nrPDB 29 3.5 3II4-A nrPDB 29 5.2 2RAA-A nrPDB 28 5.6 2GAG-B nrPDB 28 6.8 5M5J-A nrPDB 28 6.8 2YQU-A nrPDB 28 7.0 1ZUW-A nrPDB 28 8.0 >6MO6-A nrPDB Length = 414 Score = 855 bits (2208), Expect = 0.0, Method: Compositional matrix adjust. Identities = 409/409 (100%), Positives = 409/409 (100%) Query: 42 NHYEVLVLGGGSGGITMAARMKRKVGAENVAIVEPSERHFYQPIWTLVGAGAKQLSSSGR 101 NHYEVLVLGGGSGGITMAARMKRKVGAENVAIVEPSERHFYQPIWTLVGAGAKQLSSSGR Sbjct: 2 NHYEVLVLGGGSGGITMAARMKRKVGAENVAIVEPSERHFYQPIWTLVGAGAKQLSSSGR 61 Query: 102 PTASVIPSGVEWIKARVTELNPDKNCIHTDDDEKISYRYLIIALGIQLDYEKIKGLPEGF 161 PTASVIPSGVEWIKARVTELNPDKNCIHTDDDEKISYRYLIIALGIQLDYEKIKGLPEGF Sbjct: 62 PTASVIPSGVEWIKARVTELNPDKNCIHTDDDEKISYRYLIIALGIQLDYEKIKGLPEGF 121 Query: 162 AHPKIGSNYSVKTVEKTWKALQDFKEGNAIFTFPNTPVKCAGAPQKIMYLSEAYFRKTGK 221 AHPKIGSNYSVKTVEKTWKALQDFKEGNAIFTFPNTPVKCAGAPQKIMYLSEAYFRKTGK Sbjct: 122 AHPKIGSNYSVKTVEKTWKALQDFKEGNAIFTFPNTPVKCAGAPQKIMYLSEAYFRKTGK 181 Query: 222 RSKANIIFNTSLGAIFGVKKYADALQEIIQERNLTVNYKKNLIEVRADKQEAVFENLDKP 281 RSKANIIFNTSLGAIFGVKKYADALQEIIQERNLTVNYKKNLIEVRADKQEAVFENLDKP Sbjct: 182 RSKANIIFNTSLGAIFGVKKYADALQEIIQERNLTVNYKKNLIEVRADKQEAVFENLDKP 241 Query: 282 GETQVISYEMLHVTPPMSPPDVLKTSPVADAAGWVDVDKETLQHRRYPNVFGIGDCTNLP 341 GETQVISYEMLHVTPPMSPPDVLKTSPVADAAGWVDVDKETLQHRRYPNVFGIGDCTNLP Sbjct: 242 GETQVISYEMLHVTPPMSPPDVLKTSPVADAAGWVDVDKETLQHRRYPNVFGIGDCTNLP 301 Query: 342 TSKTAAAVAAQSGILDRTISVIMKNQTPTKKYDGYTSCPLVTGYNRVILAEFDYKAEPLE 401 TSKTAAAVAAQSGILDRTISVIMKNQTPTKKYDGYTSCPLVTGYNRVILAEFDYKAEPLE Sbjct: 302 TSKTAAAVAAQSGILDRTISVIMKNQTPTKKYDGYTSCPLVTGYNRVILAEFDYKAEPLE 361 Query: 402 TFPFDQSKERLSMYLMKADLMPFLYWNMMLRGYWGGPAFLRKLFHLGMS 450 TFPFDQSKERLSMYLMKADLMPFLYWNMMLRGYWGGPAFLRKLFHLGMS Sbjct: 362 TFPFDQSKERLSMYLMKADLMPFLYWNMMLRGYWGGPAFLRKLFHLGMS 410 >3HYW-A nrPDB Length = 430 Score = 69.7 bits (169), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 64/272 (23%), Positives = 120/272 (44%), Gaps = 25/272 (9%) Query: 82 YQPIWTLVGAGAKQLSSSGRPTASVIPS-GVEWIKARVTELNPDKNCIHTDDDEKISYRY 140 + P + + G ++ P A ++P +E+I + ++PD N + T +KI Y Y Sbjct: 41 FTPAFPHLAMGWRKFEDISVPLAPLLPKFNIEFINEKAESIDPDANTVTTQSGKKIEYDY 100 Query: 141 LIIALGIQLDYEKIKGLPEGFAHPKIGSNYSVKTVE---KTWKALQDFKEGNAIFTFPNT 197 L+IA G +L + A + ++ S+ T E +T K LQ+ Sbjct: 101 LVIATGPKLVFG---------AEGQEENSTSICTAEHALETQKKLQELYANPGPVVIGAI 151 Query: 198 P-VKCAGAPQKIMYLSEAYFRKTGKRSKANIIFNTS---LG--AIFGVKKYADALQEIIQ 251 P V C G + + +K G R K + F TS LG + G+ ++++ Sbjct: 152 PGVSCFGPAYEFALMLHYELKKRGIRYKVPMTFITSEPYLGHFGVGGIGASKRLVEDLFA 211 Query: 252 ERNLTVNYKKNLIEVRADKQEAVFENLDKPGETQVISYEMLHVTPPMSPPDVLKTS--PV 309 ERN +++ N+ + + ++E+L+ G T + + P P+V+ ++ V Sbjct: 212 ERN--IDWIANVAVKAIEPDKVIYEDLN--GNTHEVPAKFTMFMPSFQGPEVVASAGDKV 267 Query: 310 ADAAGWVDVDKETLQHRRYPNVFGIGDCTNLP 341 A+ A + + Q+ Y N+FG+G T +P Sbjct: 268 ANPANKMVIVNRCFQNPTYKNIFGVGVVTAIP 299 >3H8L-A nrPDB Length = 409 Score = 62.4 bits (150), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 74/334 (22%), Positives = 143/334 (42%), Gaps = 55/334 (16%) Query: 45 EVLVLGGGSGGITMAARMKRKVGAE-NVAIVEPSERHFYQPIWTLVGAGAKQLSSSGRPT 103 +VLVLGG G +T A +KR VG++ +V ++ S +++P V G + + Sbjct: 3 KVLVLGGRFGALTAAYTLKRLVGSKADVKVINKSRFSYFRPALPHVAIGVRDVDELKVDL 62 Query: 104 ASVIPS-GVEWIKARVTELNPDKNCI-HTDDDEKIS---YRYLIIALGIQLDYEKIKGLP 158 + +P G+++ + V +++ + + +T D ++ Y Y+I+ +G L E +KG Sbjct: 63 SEALPEKGIQFQEGTVEKIDAKSSMVYYTKPDGSMAEEEYDYVIVGIGAHLATELVKGW- 121 Query: 159 EGFAHPKIGSNYSVKTVEKTWKALQDFKEGN-AIFT-----------------FPNTPVK 200 + + + ++ K EK L+ F+ GN AI + PN Sbjct: 122 DKYGYSVCEPEFATKLREK----LESFQGGNIAIGSGPFYQGHNPKPKVPENFVPNADSA 177 Query: 201 CAGAPQKIMYLSEAYFRKTGKRSKANIIFNTSLGAIFGVKKYAD--------ALQEIIQE 252 C G ++ + YF+K G K ++ +F +Y A+ I + Sbjct: 178 CEGPVFEMSLMLHGYFKKKGMLDKVHV-------TVFSPGEYLSDLSPNSRKAVASIYNQ 230 Query: 253 RNLTVNYKKNLIEVRADKQEAVFENLDKPGETQVISYEMLHVTPPMSPPDVLKTS--PVA 310 + + + + E+R E +D+ G T I ++ + PP + LK S + Sbjct: 231 LGIKLVHNFKIKEIRE------HEIVDEKGNT--IPADITILLPPYTGNPALKNSTPDLV 282 Query: 311 DAAGWVDVDKETLQHRRYPNVFGIGDCTNLPTSK 344 D G++ D + +Y NV+ +GD ++ K Sbjct: 283 DDGGFIPTDLNMVS-IKYDNVYAVGDANSMTVPK 315 >3T14-A nrPDB Length = 437 Score = 58.5 bits (140), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 69/303 (22%), Positives = 125/303 (41%), Gaps = 27/303 (8%) Query: 41 RNHYEVLVLGGGSGGITMAARMKRKVGA-ENVAIVEPSERHFYQPIWTLVGAGAKQLSSS 99 R V++LG G+GG+ A MK +G+ V ++ ++ + P VG G K+ Sbjct: 2 RGSAHVVILGAGTGGMPAAYEMKEALGSGHEVTLISANDYFQFVPSNPWVGVGWKERDDI 61 Query: 100 GRPTASVIP-SGVEWIKARVTELNPDKNCIHTDDDEKISYRYLIIALGIQLDYEKIKGLP 158 P + G+ +I +++ + I D + Y YL+IA G +L +E + G Sbjct: 62 AFPIRHYVERKGIHFIAQSAEQIDAEAQNITLADGNTVHYDYLMIATGPKLAFENVPG-- 119 Query: 159 EGFAHPKIGSNYSVKTVEKTWKALQDF----KEGNAIFTFPNTPVKCAGAPQKIMYLSEA 214 + P G S+ TV+ +A ++ +E I C G + + + Sbjct: 120 ---SDPHEGPVQSIATVDHAERAFAEYQALLREPGPIVIGAMAGASCFGPAYEYAMIVAS 176 Query: 215 YFRKTGKRSK-ANIIFNTSLGAI--FGVKKYADA---LQEIIQERNLTVNYKKNLIEVRA 268 +K G R K + F TS I G++ D+ L + ++E + + +V Sbjct: 177 DLKKRGMRDKIPSFTFITSEPYIGHLGIQGVGDSKGILTKGLKEEGIEAYTNCKVTKVED 236 Query: 269 DKQEAVFENLDKPGET---QVISYEMLHVTPPMSP-PDVLKTSPVADAAGWVDVDKETLQ 324 +K +D+ GET V+ + + P P V + + G+V VD + Sbjct: 237 NKMYVT--QVDEKGETIKEMVLPVKFGMMIPAFKGVPAVAGVEGLCNPGGFVLVD----E 290 Query: 325 HRR 327 H+R Sbjct: 291 HQR 293 >1FCD-A nrPDB Length = 401 Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 71/312 (22%), Positives = 134/312 (42%), Gaps = 26/312 (8%) Query: 71 VAIVEPSERHFYQPIWTLVGAGAKQLSSSGRPTASVIPSGVEWIKARVTELNPDKNCIHT 130 V ++EP+ ++ + V G ++L S + G++ + T ++PDK + T Sbjct: 30 VTLIEPNTDYYTCYLSNEVIGGDRKLESIKHGYDGLRAHGIQVVHDSATGIDPDKKLVKT 89 Query: 131 DDDEKISYRYLIIALGIQLDYEKIKGLPEGFAHPKIGSNYSVKTVEKTW---KALQDFKE 187 + Y ++A GI+L Y+KI+G E A K+ ++ K E+T K L+D + Sbjct: 90 AGGAEFGYDRCVVAPGIELIYDKIEGYSEE-AAAKL--PHAWKAGEQTAILRKQLEDMAD 146 Query: 188 GNAIFTF-PNTPVKCAGAPQKIMYLSEAYFRKTGKRSKANIIFNTSLGAIFGVKKYADAL 246 G + P P +C P + AY+ K K II ++S + ++ Sbjct: 147 GGTVVIAPPAAPFRCPPGPYE-RASQVAYYLKAHKPMSKVIILDSS-------QTFSKQS 198 Query: 247 Q-EIIQERNLTVNYKKNLIEVRADKQEAVFENLDKPGETQV-------ISYEMLHVTPPM 298 Q ER + +IE AV + +D GE V +++++ PP Sbjct: 199 QFSKGWERLYGFGTENAMIEWHPGPDSAVVK-VDG-GEMMVETAFGDEFKADVINLIPPQ 256 Query: 299 SPPDVLKTSPVADAAGWVDVDKETLQHRRYPNVFGIGDCTNL-PTSKTAAAVAAQSGILD 357 + + + + + AGW VD +T + + + IGD + P K+ + +Q + Sbjct: 257 RAGKIAQIAGLTNDAGWCPVDIKTFESSIHKGIHVIGDASIANPMPKSGYSANSQGKVAA 316 Query: 358 RTISVIMKNQTP 369 + V++K + P Sbjct: 317 AAVVVLLKGEEP 328 >3VRD-B nrPDB Length = 401 Score = 52.4 bits (124), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 79/340 (23%), Positives = 141/340 (41%), Gaps = 23/340 (6%) Query: 71 VAIVEPSERHFYQPIWTLVGAGAKQLSSSGRPTASVIPSGVEWIKARVTELNPDKNCIHT 130 V ++EP+E ++ + V G ++L+S + G++ + ++PDK + T Sbjct: 30 VTLIEPNETYYTCYMSNEVIGGDRELASLRVGYDGLRAHGIQVVHDSALGIDPDKKLVKT 89 Query: 131 DDDEKISYRYLIIALGIQLDYEKIKGLPEGFAHPKIGSNYSVKTVEKTW---KALQDFKE 187 + +Y ++A GI L Y+KI+G E A K+ ++ K E+T + L+ + Sbjct: 90 AGGAEFAYDRCVVAPGIDLLYDKIEGYSEALA-AKL--PHAWKAGEQTALLRRQLESMDD 146 Query: 188 GN-AIFTFPNTPVKCAGAPQKIMYLSEAYFRKTGKRSKANIIFNTSLGAIFGVKKYADAL 246 G I P P +C P + Y + +SK I+ N+ K A Sbjct: 147 GGVVIIAPPAPPFRCPPGPYERASQIAHYLKAHKSKSKVIILDNSQT-----FSKQAQFT 201 Query: 247 QEIIQERNLTVNYKKNLIEVRADKQEAVFENLDKPGETQVISY------EMLHVTPPMSP 300 + ER + LIE AV + D T S+ ++++ PP Sbjct: 202 KG--WERLYGFGTENALIEWHPGPDAAVVKT-DTEAMTVETSFGETFKAAVINLIPPQRA 258 Query: 301 PDVLKTSPVADAAGWVDVDKETLQHRRYPNVFGIGD-CTNLPTSKTAAAVAAQSGILDRT 359 + +++ + + +GW VD T + P + IGD C P K+A + +Q+ + Sbjct: 259 GKIAQSASLTNDSGWCPVDIRTFESSLQPGIHVIGDACNAAPMPKSAYSANSQAKVAAAA 318 Query: 360 ISVIMKNQTP-TKKYDGYTSCPLVTGYNRVILAEFDYKAE 398 + ++K + P T Y L GY I A + AE Sbjct: 319 VVALLKGEEPGTPSYLNTCYSILAPGYGISIAAVYRPNAE 358 >5N1T-A nrPDB Length = 429 Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 67/318 (21%), Positives = 129/318 (40%), Gaps = 31/318 (9%) Query: 32 LHTGASHAARNHYEVLVLGGGSGGITMAARMKRKVGAE-NVAIVEPSERHFYQPIWTLVG 90 +H + A R G + AR R + V ++ PS+ + P LV Sbjct: 30 MHDSGNKAQRVVVIGGGF-----GGSTCARYLRHFDPDLEVTLINPSDTYTTCPFSNLVL 84 Query: 91 AGAKQLSSSGRPTASV-IPSGVEWIKARVTELNPDKNCIHTDDDEKISYRYLIIALGIQL 149 G + L+S + + GV ++ V ++ D + + DD I Y L+++ GI L Sbjct: 85 GGERDLASITHDLSQLEHHHGVRLVQRWVESIDADGHRVVLDDGSAIGYDRLVVSPGIDL 144 Query: 150 DYEKIKGLPEGFAHPKIGSNYSVKTVEKTW---KALQDFKEGNAIFTF-PNTPVKCAGAP 205 ++ ++G + + ++ + E+T + L+ +G + P P +C P Sbjct: 145 RWDAVEGYDQA---AQEAMPHAWRPGEQTLLLRRQLEAMSDGGVVVIAPPANPFRCPPGP 201 Query: 206 QKIMYLSEAYFRKTGKRSKANIIFNTSLGAIFGVKKYADALQEIIQERNLTVNYKKNLIE 265 + L Y + RSK I+ K A A Q + Q T+ +IE Sbjct: 202 YERASLIAHYLKHHKPRSKILIL----------DAKDAFAKQGLFQTGWETL--YPGMIE 249 Query: 266 VRADKQEAVFENLDKP-GETQVIS----YEMLHVTPPMSPPDVLKTSPVADAAGWVDVDK 320 + E +D GE S +++++ PP + + + + D +GW V++ Sbjct: 250 WVPGIEGGTVERVDAATGEVFTPSGRYRGDVVNLIPPQHAGAIARNTGLTDDSGWCPVNQ 309 Query: 321 ETLQHRRYPNVFGIGDCT 338 +T + + P++ IGD + Sbjct: 310 QTFESLQIPHIHVIGDAS 327 >5NA1-A nrPDB Length = 408 Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust. Identities = 30/124 (24%), Positives = 60/124 (48%), Gaps = 6/124 (4%) Query: 40 ARNHYEVLVLGGGSGGITMAARMKRKVGAE--NVAIVEPSERHFYQPIWT-LVGAGAKQL 96 A++ +VLVLG G G+ ++++ + E + ++ +E H Y+ W AG Sbjct: 8 AQDRKKVLVLGAGYAGLQTVTKLQKAISTEEAEITLINKNEYH-YEATWLHEASAGTLNY 66 Query: 97 SSSGRPTASVIPSG-VEWIKARVTELNPDKNCIHTDDDEKISYRYLIIALGIQLDYEKIK 155 P SV+ V +++A VT+++ D + T+ + L++ALG + I+ Sbjct: 67 EDVLYPVESVLKKDKVNFVQAEVTKIDRDAKKVETNQG-IYDFDILVVALGFVSETFGIE 125 Query: 156 GLPE 159 G+ + Sbjct: 126 GMKD 129 >4G74-A nrPDB Length = 502 Score = 38.9 bits (89), Expect = 0.004, Method: Compositional matrix adjust. Identities = 33/137 (24%), Positives = 53/137 (38%), Gaps = 25/137 (18%) Query: 46 VLVLGGGSGGITMAARMKRKVGAENVAIVEPSERHFYQPIWTLVGAGAKQLSSSGRPTAS 105 VL+LG G G I+ + K NV+I+ P + P+ G S P + Sbjct: 45 VLILGSGWGAISFLKHIDTK--KYNVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIVN 102 Query: 106 VI---PSGVEWIKARVTELNPDKNCI--------------------HTDDDEKISYRYLI 142 V + +A T +NPD+N + H + +I Y YLI Sbjct: 103 FALKKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYLI 162 Query: 143 IALGIQLDYEKIKGLPE 159 A+G + + I G+ + Sbjct: 163 SAVGAEPNTFGIPGVTD 179 >5JWC-A nrPDB Length = 521 Score = 37.4 bits (85), Expect = 0.015, Method: Compositional matrix adjust. Identities = 71/325 (21%), Positives = 134/325 (41%), Gaps = 43/325 (13%) Query: 45 EVLVLGGGSGGITMAARMKRKVGAENVAIVEPSERHFYQPIWTLVGAGAKQLSSSGRPTA 104 ++++LG G GG + K +V ++ P + P+ + +G ++ Sbjct: 30 KIIILGSGWGGFNFLLNIDFK--KYDVTLISPRNYFTFTPLLPCLCSGTLSVNVCTESIR 87 Query: 105 SVI--PSGV--EWIKARVTEL-NPDK--NCIHTDDDE-KISYRYLIIALGIQLDYEKIKG 156 + + +G +++ T++ DK NCI ++++ K+ Y YLIIA+G + + I G Sbjct: 88 NFLRKKNGYCGNYLQLECTDVFYEDKYINCIDIENNKVKLFYDYLIIAVGAKTNTFNING 147 Query: 157 LPEGFAHPKIGSNYSVKTVEKTWKALQDFKEGNAIFTFPNTPVK----------CAGAPQ 206 + + +A Y VK ++ K + F + T PN + G P Sbjct: 148 V-DKYA-------YFVKDIDDALKIRKKFLDILEKCTLPNISNEEKKKMLHVAVVGGGPT 199 Query: 207 KIMYLSE--AYFRKTGKRSKANIIFNTSLGAIFG----VKKYADALQEIIQE--RNLTVN 258 + +E + K K + +I S+ I G + + + + +E NL +N Sbjct: 200 GVEVTAEFADFINKEVKINYKDIFNFISISIIEGGNNLLPTFTQNISDFTKENFHNLNIN 259 Query: 259 YKKNLIEVRADKQEAVFENLDKPGETQVISYEMLHVTPPMSPPDV----LKTSPVADAAG 314 N + DK ++ E + +SY +L ++ + LKT PV Sbjct: 260 VLTNYYVIDVDKHSFHIQSSLNKNEKKKLSYGLLIWASGLAQTTLIQKFLKTIPVQANNA 319 Query: 315 WVDVDKETLQHRRYP--NVFGIGDC 337 + VD E L+ P N++ IGDC Sbjct: 320 ILKVD-EKLRVIGIPSNNIYAIGDC 343 >3F8P-A nrPDB Length = 323 Score = 37.4 bits (85), Expect = 0.015, Method: Compositional matrix adjust. Identities = 31/100 (31%), Positives = 49/100 (49%), Gaps = 14/100 (14%) Query: 265 EVRADK--QEAVFENLDKPGETQVISYEMLHVTPPMSPP-DVLKTSPV-ADAAGWVDVDK 320 E++ DK ++ V ENL K GE + ++ + + PP D K++ + D G++ VD+ Sbjct: 215 EIKGDKVVKQVVVENL-KTGEIKELNVNGVFIEIGFDPPTDFAKSNGIETDTNGYIKVDE 273 Query: 321 ETLQHRRYPNVFGIGDCTN-------LPTSKTAAAVAAQS 353 P VF GDCT+ + T+ AVAA S Sbjct: 274 --WMRTSVPGVFAAGDCTSAWLGFRQVITAVAQGAVAATS 311 >5MJK-A nrPDB Length = 327 Score = 35.8 bits (81), Expect = 0.042, Method: Compositional matrix adjust. Identities = 81/342 (23%), Positives = 127/342 (37%), Gaps = 75/342 (21%) Query: 36 ASHAARNHYEVLVLGGGSGGITMA---ARMKRKV-----GAENVAIVEPSERHFYQPIWT 87 SH Y+V+++G G G+T A AR + K G + +E Y T Sbjct: 17 GSHMTEKKYDVVIIGSGPAGMTAAMYTARSEMKTLLLERGVPGGQMNNTAEIENYPGYET 76 Query: 88 LVG-----AGAKQLSSSGRPTASVIPSGVEWIKARVTELNPDKNCIHTDDDEKISYRYLI 142 ++G A+ L G A +G+ E + D I T+DDE I+ + +I Sbjct: 77 IMGPELSMKMAEPLEGLGVENAYGFVTGI--------EDHGDYKKIITEDDEFIT-KSII 127 Query: 143 IALGIQLDYEKIKGLPEGFAHPKIGSNYSVKTVEKTWKALQDFKEGNAIFTFPNTPVKCA 202 IA G +I G E Y + V ++ A+ D F F N + Sbjct: 128 IATGANHRKLEIPGEEE----------YGARGV--SYCAVCD-----GAF-FRNQEILVI 169 Query: 203 GAPQKIMYLSEAYFRKTGKRSKANIIFNTSLGAIFGVKKYADAL--QEIIQERNLTVNYK 260 G G + ++ T G + D L QEIIQ+R K Sbjct: 170 GG---------------GDSAVEEALYLTRFGQSVTIMHRRDKLRAQEIIQQRAFK-EEK 213 Query: 261 KNLI------EVRADK---QEAVFENLDKPGETQVISYEMLHVTPPMSP-PDVLKTSPVA 310 N I E++ D Q V++N+ K GE ++ + + + P + + + Sbjct: 214 INFIWDSVPMEIKGDDKKIQSVVYKNV-KTGEVTEKAFGGIFIYVGLDPVAEFVSDLGIT 272 Query: 311 DAAGWVDVDKETLQHRR--YPNVFGIGDCTNLPTSKTAAAVA 350 D AGW+ D H R P +F +GD + AV Sbjct: 273 DEAGWIITD----DHMRTNIPGIFAVGDVRQKDFRQITTAVG 310 >5I68-A nrPDB Length = 663 Score = 32.7 bits (73), Expect = 0.31, Method: Compositional matrix adjust. Identities = 16/47 (34%), Positives = 25/47 (53%) Query: 44 YEVLVLGGGSGGITMAARMKRKVGAENVAIVEPSERHFYQPIWTLVG 90 +++LVLGGGS G +A R+ + V ++E E + P L G Sbjct: 7 FDILVLGGGSSGSCIAGRLANLDHSLKVGLIEAGENNLNNPWVYLPG 53 >1ZDL-A nrPDB Length = 517 Score = 31.2 bits (69), Expect = 0.89, Method: Compositional matrix adjust. Identities = 21/56 (37%), Positives = 33/56 (58%), Gaps = 7/56 (12%) Query: 29 PLQLHTGASHAA--RNHYEVLVLGGGSGGITM---AARMKRKVGAENVAIVEPSER 79 P H ++ AA + +++LV+GGGSGG+ AA++ +KV + VEPS R Sbjct: 16 PRGSHMASASAAGGQQSFDLLVIGGGSGGLACAKEAAQLGKKVAVAD--YVEPSPR 69 >2DWU-A nrPDB Length = 276 Score = 30.0 bits (66), Expect = 2.1, Method: Compositional matrix adjust. Identities = 14/46 (30%), Positives = 25/46 (54%) Query: 39 AARNHYEVLVLGGGSGGITMAARMKRKVGAENVAIVEPSERHFYQP 84 H + VL G GG+T+A+ + R++ E++ + +ER Y P Sbjct: 3 VCHKHSVIGVLDSGVGGLTVASEIIRQLPKESICYIGDNERCPYGP 48 >3VML-A nrPDB Length = 375 Score = 30.0 bits (66), Expect = 2.1, Method: Compositional matrix adjust. Identities = 15/50 (30%), Positives = 25/50 (50%) Query: 318 VDKETLQHRRYPNVFGIGDCTNLPTSKTAAAVAAQSGILDRTISVIMKNQ 367 +D T+Q R PN F + C+NL + +A +G + S+ M +Q Sbjct: 235 IDNATMQLLRRPNEFDVMLCSNLFGDIVSDEIAMLTGSMGLLASISMNSQ 284 >3VMK-A nrPDB Length = 375 Score = 30.0 bits (66), Expect = 2.2, Method: Compositional matrix adjust. Identities = 15/50 (30%), Positives = 25/50 (50%) Query: 318 VDKETLQHRRYPNVFGIGDCTNLPTSKTAAAVAAQSGILDRTISVIMKNQ 367 +D T+Q R PN F + C+NL + +A +G + S+ M +Q Sbjct: 235 IDNATMQLLRRPNEFDVMLCSNLFGDIVSDEIAMLTGSMGLLASISMNSQ 284 >3V7P-A nrPDB Length = 427 Score = 29.6 bits (65), Expect = 2.9, Method: Compositional matrix adjust. Identities = 15/34 (44%), Positives = 19/34 (55%) Query: 149 LDYEKIKGLPEGFAHPKIGSNYSVKTVEKTWKAL 182 LD EKIK +P A + SNYS+ E+ AL Sbjct: 291 LDLEKIKSIPYAIATDGLSSNYSLNMYEELKAAL 324 >4Y1B-A nrPDB Length = 425 Score = 29.3 bits (64), Expect = 3.5, Method: Compositional matrix adjust. Identities = 18/49 (36%), Positives = 24/49 (48%) Query: 31 QLHTGASHAARNHYEVLVLGGGSGGITMAARMKRKVGAENVAIVEPSER 79 QL H R VL+ GG G ++A ++ R VG VA+V ER Sbjct: 210 QLFGWEPHTVRPGDPVLIWGGAGGLGSIAIQLVRHVGGIPVAVVSSEER 258 >3II4-A nrPDB Length = 466 Score = 28.9 bits (63), Expect = 5.2, Method: Compositional matrix adjust. Identities = 16/34 (47%), Positives = 20/34 (58%), Gaps = 2/34 (5%) Query: 43 HYEVLVLGGGSGGITMAARMKRKVGAENVAIVEP 76 HY+V+VLG G GG A R + + AIVEP Sbjct: 5 HYDVVVLGAGPGGYVAAIRAAQL--GLSTAIVEP 36 >2RAA-A nrPDB Length = 204 Score = 28.5 bits (62), Expect = 5.6, Method: Compositional matrix adjust. Identities = 32/109 (29%), Positives = 45/109 (41%), Gaps = 24/109 (22%) Query: 99 SGRPTASVIPSGVEWIKARVTELNPDKNCIHTDDDEKISYRYLIIAL---GIQL-----D 150 +G P + G E+I+ R NPD + DE + ++ L GI L D Sbjct: 61 TGAPMRAFNRIGDEYIRVRSAVENPDVVVVI---DETLLSPAIVEGLSEDGILLVNTVKD 117 Query: 151 YEKIKGLPEGFAHPKIGSNYSVKTVEKTWKALQDFKEGNAIFTFPNTPV 199 +E F K G N + V+ T ALQ+ K G PNTP+ Sbjct: 118 FE--------FVRKKTGFNGKICVVDATDIALQEIKRG-----IPNTPM 153 >2GAG-B nrPDB Length = 405 Score = 28.5 bits (62), Expect = 6.8, Method: Compositional matrix adjust. Identities = 11/32 (34%), Positives = 20/32 (62%) Query: 44 YEVLVLGGGSGGITMAARMKRKVGAENVAIVE 75 Y+ +++GGG G+ A + + G NVA++E Sbjct: 22 YDAIIVGGGGHGLATAYFLAKNHGITNVAVLE 53 >5M5J-A nrPDB Length = 325 Score = 28.5 bits (62), Expect = 6.8, Method: Compositional matrix adjust. Identities = 28/114 (24%), Positives = 52/114 (45%), Gaps = 8/114 (7%) Query: 246 LQEIIQERNLTVNYKKNLIEVRADKQ---EAVFENLDKPGETQVISYEMLHVTPPMSP-P 301 +++++ E+ + + Y + E++ D + +NL K G+T+ ++ L+ P Sbjct: 200 VKKVMNEKLIEIIYDSAIDEIKGDGKCVTSVSIKNL-KDGKTRTLNAGALYWAVGHDPQT 258 Query: 302 DVLKTSPVA-DAAGWVDVDKETLQHRRYPNVFGIGDCTNLPTSKTAAAVAAQSG 354 LK + D AG++ + Q VF GDC + + A VAA SG Sbjct: 259 SFLKKGQLEQDEAGYILLKDHPTQRTSVDGVFAAGDCCDHLYRQ--AVVAAGSG 310 >2YQU-A nrPDB Length = 455 Score = 28.5 bits (62), Expect = 7.0, Method: Compositional matrix adjust. Identities = 37/166 (22%), Positives = 66/166 (39%), Gaps = 44/166 (26%) Query: 44 YEVLVLGGGSGGITM---AARMKRKVGA-----------------ENVAIVEPSERHFYQ 83 Y++LV+G G GG AA++ KVG + A++E +ER Y+ Sbjct: 2 YDLLVIGAGPGGYVAAIRAAQLGMKVGVVEKEKALGGTCLRVGCIPSKALLETTER-IYE 60 Query: 84 PIWTLVGAGAK-------QLSSSGRPTASVIPSGVEWIKAR--------VTELNPDKNCI 128 L+GA K L + GVE++ + ++ + Sbjct: 61 AKKGLLGAKVKGVELDLPALMAHKDKVVQANTQGVEFLFKKNGIARHQGTARFLSERKVL 120 Query: 129 HTDDDEKISYRYLIIALG--------IQLDYEKIKGLPEGFAHPKI 166 + E++ RY++IA G Q+DYE++ E + P++ Sbjct: 121 VEETGEELEARYILIATGSAPLIPPWAQVDYERVVTSTEALSFPEV 166 >1ZUW-A nrPDB Length = 272 Score = 28.1 bits (61), Expect = 8.0, Method: Compositional matrix adjust. Identities = 13/37 (35%), Positives = 22/37 (59%) Query: 48 VLGGGSGGITMAARMKRKVGAENVAIVEPSERHFYQP 84 V+ G GG+T+A + R++ EN+ V ++R Y P Sbjct: 8 VIDSGVGGLTVAKEIMRQLPKENIIYVGDTKRCPYGP 44 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6MO6-A nrPDB 595 e-170 1FCD-A nrPDB 362 e-100 5N1T-A nrPDB 353 1e-97 3VRD-B nrPDB 345 2e-95 3T14-A nrPDB 284 6e-77 3HYW-A nrPDB 274 5e-74 3H8L-A nrPDB 272 2e-73 5NA1-A nrPDB 144 8e-35 Sequences not found previously or not previously below threshold: 4G74-A nrPDB 80 2e-15 3KLJ-A nrPDB 64 9e-11 1NHQ-A nrPDB 60 3e-09 3IWA-A nrPDB 57 2e-08 3CGD-A nrPDB 56 3e-08 1EBD-A nrPDB 56 4e-08 5JWC-A nrPDB 56 4e-08 1XHC-A nrPDB 56 4e-08 3FG2-P nrPDB 55 6e-08 3LXD-A nrPDB 53 2e-07 2BC1-A nrPDB 51 8e-07 5MJK-A nrPDB 51 9e-07 2CDU-A nrPDB 51 1e-06 2YVG-A nrPDB 50 3e-06 5ER0-A nrPDB 49 5e-06 3F8P-A nrPDB 46 2e-05 1Q1R-A nrPDB 46 3e-05 3OC4-A nrPDB 46 3e-05 4EMJ-A nrPDB 46 3e-05 3ICS-A nrPDB 45 6e-05 4NTC-A nrPDB 43 3e-04 1V59-A nrPDB 43 3e-04 2YQU-A nrPDB 42 4e-04 5J5Z-A nrPDB 41 0.001 4FX9-A nrPDB 40 0.002 1FOB-A nrPDB 39 0.003 5JCN-A nrPDB 39 0.005 1ZK7-A nrPDB 39 0.005 2WOV-A nrPDB 38 0.008 5YGQ-A nrPDB 37 0.011 4ZN0-A nrPDB 37 0.018 2A87-A nrPDB 37 0.020 5VDN-A nrPDB 36 0.031 4JDR-A nrPDB 36 0.044 6B4O-A nrPDB 36 0.050 5U25-A nrPDB 36 0.050 1F8S-A nrPDB 36 0.051 5W1J-A nrPDB 35 0.056 1REO-A nrPDB 35 0.057 1OJT-A nrPDB 35 0.057 3Q6J-A nrPDB 35 0.062 4YKF-A nrPDB 34 0.12 1FL2-A nrPDB 34 0.12 5KVH-A nrPDB 34 0.14 1GEU-A nrPDB 33 0.28 3KVE-A nrPDB 33 0.33 4JNQ-A nrPDB 32 0.47 4UIR-A nrPDB 32 0.61 3UKH-A nrPDB 32 0.65 5M5J-A nrPDB 31 0.82 6N7F-A nrPDB 31 0.92 5MIU-A nrPDB 31 0.93 3NTA-A nrPDB 31 1.2 1JNS-A nrPDB 31 1.2 2R9Z-A nrPDB 30 1.6 2EQ6-A nrPDB 30 1.7 2DWU-A nrPDB 30 2.0 4Z44-A nrPDB 30 2.1 3LOV-A nrPDB 30 2.2 5MLK-A nrPDB 30 2.6 4G2C-A nrPDB 29 3.4 3RBN-A nrPDB 29 3.8 3O4F-A nrPDB 29 4.6 5ZHA-A nrPDB 29 4.7 2GMH-A nrPDB 29 6.2 2GAG-B nrPDB 28 8.3 1XJ5-A nrPDB 28 9.2 >6MO6-A nrPDB Length = 414 Score = 595 bits (1533), Expect = e-170, Method: Composition-based stats. Identities = 409/409 (100%), Positives = 409/409 (100%) Query: 42 NHYEVLVLGGGSGGITMAARMKRKVGAENVAIVEPSERHFYQPIWTLVGAGAKQLSSSGR 101 NHYEVLVLGGGSGGITMAARMKRKVGAENVAIVEPSERHFYQPIWTLVGAGAKQLSSSGR Sbjct: 2 NHYEVLVLGGGSGGITMAARMKRKVGAENVAIVEPSERHFYQPIWTLVGAGAKQLSSSGR 61 Query: 102 PTASVIPSGVEWIKARVTELNPDKNCIHTDDDEKISYRYLIIALGIQLDYEKIKGLPEGF 161 PTASVIPSGVEWIKARVTELNPDKNCIHTDDDEKISYRYLIIALGIQLDYEKIKGLPEGF Sbjct: 62 PTASVIPSGVEWIKARVTELNPDKNCIHTDDDEKISYRYLIIALGIQLDYEKIKGLPEGF 121 Query: 162 AHPKIGSNYSVKTVEKTWKALQDFKEGNAIFTFPNTPVKCAGAPQKIMYLSEAYFRKTGK 221 AHPKIGSNYSVKTVEKTWKALQDFKEGNAIFTFPNTPVKCAGAPQKIMYLSEAYFRKTGK Sbjct: 122 AHPKIGSNYSVKTVEKTWKALQDFKEGNAIFTFPNTPVKCAGAPQKIMYLSEAYFRKTGK 181 Query: 222 RSKANIIFNTSLGAIFGVKKYADALQEIIQERNLTVNYKKNLIEVRADKQEAVFENLDKP 281 RSKANIIFNTSLGAIFGVKKYADALQEIIQERNLTVNYKKNLIEVRADKQEAVFENLDKP Sbjct: 182 RSKANIIFNTSLGAIFGVKKYADALQEIIQERNLTVNYKKNLIEVRADKQEAVFENLDKP 241 Query: 282 GETQVISYEMLHVTPPMSPPDVLKTSPVADAAGWVDVDKETLQHRRYPNVFGIGDCTNLP 341 GETQVISYEMLHVTPPMSPPDVLKTSPVADAAGWVDVDKETLQHRRYPNVFGIGDCTNLP Sbjct: 242 GETQVISYEMLHVTPPMSPPDVLKTSPVADAAGWVDVDKETLQHRRYPNVFGIGDCTNLP 301 Query: 342 TSKTAAAVAAQSGILDRTISVIMKNQTPTKKYDGYTSCPLVTGYNRVILAEFDYKAEPLE 401 TSKTAAAVAAQSGILDRTISVIMKNQTPTKKYDGYTSCPLVTGYNRVILAEFDYKAEPLE Sbjct: 302 TSKTAAAVAAQSGILDRTISVIMKNQTPTKKYDGYTSCPLVTGYNRVILAEFDYKAEPLE 361 Query: 402 TFPFDQSKERLSMYLMKADLMPFLYWNMMLRGYWGGPAFLRKLFHLGMS 450 TFPFDQSKERLSMYLMKADLMPFLYWNMMLRGYWGGPAFLRKLFHLGMS Sbjct: 362 TFPFDQSKERLSMYLMKADLMPFLYWNMMLRGYWGGPAFLRKLFHLGMS 410 >1FCD-A nrPDB Length = 401 Score = 362 bits (929), Expect = e-100, Method: Composition-based stats. Identities = 75/350 (21%), Positives = 142/350 (40%), Gaps = 27/350 (7%) Query: 70 NVAIVEPSERHFYQPIWTLVGAGAKQLSSSGRPTASVIPSGVEWIKARVTELNPDKNCIH 129 V ++EP+ ++ + V G ++L S + G++ + T ++PDK + Sbjct: 29 EVTLIEPNTDYYTCYLSNEVIGGDRKLESIKHGYDGLRAHGIQVVHDSATGIDPDKKLVK 88 Query: 130 TDDDEKISYRYLIIALGIQLDYEKIKGLPEGFAHPKIGSNYSVKTVEKTW---KALQDFK 186 T + Y ++A GI+L Y+KI+G E A ++ K E+T K L+D Sbjct: 89 TAGGAEFGYDRCVVAPGIELIYDKIEGYSEEAAA---KLPHAWKAGEQTAILRKQLEDMA 145 Query: 187 EGNAIFT-FPNTPVKCAGAPQKIMYLSEAYFRKTGKRSKANIIFNTSLGAIFGVKKYADA 245 +G + P P +C P + Y + SK I+ ++ K + Sbjct: 146 DGGTVVIAPPAAPFRCPPGPYERASQVAYYLKAHKPMSKVIILDSSQT-----FSKQSQF 200 Query: 246 LQEIIQERNLTVNYKKNLIEVRADKQEAVFENLDKPGETQV-------ISYEMLHVTPPM 298 + ER + +IE AV + +D GE V +++++ PP Sbjct: 201 SKG--WERLYGFGTENAMIEWHPGPDSAVVK-VDG-GEMMVETAFGDEFKADVINLIPPQ 256 Query: 299 SPPDVLKTSPVADAAGWVDVDKETLQHRRYPNVFGIGDCTNL-PTSKTAAAVAAQSGILD 357 + + + + + AGW VD +T + + + IGD + P K+ + +Q + Sbjct: 257 RAGKIAQIAGLTNDAGWCPVDIKTFESSIHKGIHVIGDASIANPMPKSGYSANSQGKVAA 316 Query: 358 RTISVIMKNQTP-TKKYDGYTSCPLVTGYNRVILAEFDYKAE--PLETFP 404 + V++K + P T Y L Y + A + A+ +E+ P Sbjct: 317 AAVVVLLKGEEPGTPSYLNTCYSILAPAYGISVAAIYRPNADGSAIESVP 366 >5N1T-A nrPDB Length = 429 Score = 353 bits (905), Expect = 1e-97, Method: Composition-based stats. Identities = 76/376 (20%), Positives = 147/376 (39%), Gaps = 33/376 (8%) Query: 32 LHTGASHAARNHYEVLVLGGGSGGITMAARMKRKVGAE-NVAIVEPSERHFYQPIWTLVG 90 +H + A R GG G + AR R + V ++ PS+ + P LV Sbjct: 30 MHDSGNKAQRVVVI-----GGGFGGSTCARYLRHFDPDLEVTLINPSDTYTTCPFSNLVL 84 Query: 91 AGAKQLSSSGRPTASV-IPSGVEWIKARVTELNPDKNCIHTDDDEKISYRYLIIALGIQL 149 G + L+S + + GV ++ V ++ D + + DD I Y L+++ GI L Sbjct: 85 GGERDLASITHDLSQLEHHHGVRLVQRWVESIDADGHRVVLDDGSAIGYDRLVVSPGIDL 144 Query: 150 DYEKIKGLPEGFAHPKIGSNYSVKTVEKTW---KALQDFKEGNAIFT-FPNTPVKCAGAP 205 ++ ++G + + ++ + E+T + L+ +G + P P +C P Sbjct: 145 RWDAVEGYDQA---AQEAMPHAWRPGEQTLLLRRQLEAMSDGGVVVIAPPANPFRCPPGP 201 Query: 206 QKIMYLSEAYFRKTGKRSKANIIFNTSLGAIFGVKKYADALQEIIQERNLTVNYKKNLIE 265 + L Y + RSK I+ K A A Q + Q T+ +IE Sbjct: 202 YERASLIAHYLKHHKPRSKILIL----------DAKDAFAKQGLFQTGWETLY--PGMIE 249 Query: 266 VRADKQEAVFENLDKP-GETQVIS----YEMLHVTPPMSPPDVLKTSPVADAAGWVDVDK 320 + E +D GE S +++++ PP + + + + D +GW V++ Sbjct: 250 WVPGIEGGTVERVDAATGEVFTPSGRYRGDVVNLIPPQHAGAIARNTGLTDDSGWCPVNQ 309 Query: 321 ETLQHRRYPNVFGIGDCTNL-PTSKTAAAVAAQSGILDRTISVIMKNQTPT-KKYDGYTS 378 +T + + P++ IGD + K A +Q+ + + + PT + Sbjct: 310 QTFESLQIPHIHVIGDASIAGAMPKAGFAANSQAKVCAAAVVAALHGFDPTEPSWSSTCY 369 Query: 379 CPLVTGYNRVILAEFD 394 + Y + A + Sbjct: 370 SLVGPEYGISVSAVYR 385 >3VRD-B nrPDB Length = 401 Score = 345 bits (886), Expect = 2e-95, Method: Composition-based stats. Identities = 79/349 (22%), Positives = 141/349 (40%), Gaps = 25/349 (7%) Query: 70 NVAIVEPSERHFYQPIWTLVGAGAKQLSSSGRPTASVIPSGVEWIKARVTELNPDKNCIH 129 V ++EP+E ++ + V G ++L+S + G++ + ++PDK + Sbjct: 29 EVTLIEPNETYYTCYMSNEVIGGDRELASLRVGYDGLRAHGIQVVHDSALGIDPDKKLVK 88 Query: 130 TDDDEKISYRYLIIALGIQLDYEKIKGLPEGFAHPKIGSNYSVKTVEKTW---KALQDFK 186 T + +Y ++A GI L Y+KI+G E A ++ K E+T + L+ Sbjct: 89 TAGGAEFAYDRCVVAPGIDLLYDKIEGYSEALAA---KLPHAWKAGEQTALLRRQLESMD 145 Query: 187 EGNAIFTF-PNTPVKCAGAPQKIMYLSEAYFRKTGKRSKANIIFNTSLGAIFGVKKYADA 245 +G + P P +C P + Y + +SK I+ N+ K A Sbjct: 146 DGGVVIIAPPAPPFRCPPGPYERASQIAHYLKAHKSKSKVIILDNSQT-----FSKQAQF 200 Query: 246 LQEIIQERNLTVNYKKNLIEVRADKQEAVFENLDKPGETQVIS------YEMLHVTPPMS 299 + ER + LIE AV + D T S ++++ PP Sbjct: 201 TKG--WERLYGFGTENALIEWHPGPDAAVVKT-DTEAMTVETSFGETFKAAVINLIPPQR 257 Query: 300 PPDVLKTSPVADAAGWVDVDKETLQHRRYPNVFGIGD-CTNLPTSKTAAAVAAQSGILDR 358 + +++ + + +GW VD T + P + IGD C P K+A + +Q+ + Sbjct: 258 AGKIAQSASLTNDSGWCPVDIRTFESSLQPGIHVIGDACNAAPMPKSAYSANSQAKVAAA 317 Query: 359 TISVIMKNQTP-TKKYDGYTSCPLVTGYNRVILAEFDYKAE--PLETFP 404 + ++K + P T Y L GY I A + AE +E P Sbjct: 318 AVVALLKGEEPGTPSYLNTCYSILAPGYGISIAAVYRPNAEGKAIEAVP 366 >3T14-A nrPDB Length = 437 Score = 284 bits (726), Expect = 6e-77, Method: Composition-based stats. Identities = 77/371 (20%), Positives = 137/371 (36%), Gaps = 43/371 (11%) Query: 41 RNHYEVLVLGGGSGGITMAARMKRKVGA-ENVAIVEPSERHFYQPIWTLVGAGAKQLSSS 99 R V++LG G+GG+ A MK +G+ V ++ ++ + P VG G K+ Sbjct: 2 RGSAHVVILGAGTGGMPAAYEMKEALGSGHEVTLISANDYFQFVPSNPWVGVGWKERDDI 61 Query: 100 GRPTASVIP-SGVEWIKARVTELNPDKNCIHTDDDEKISYRYLIIALGIQLDYEKIKGLP 158 P + G+ +I +++ + I D + Y YL+IA G +L +E + G Sbjct: 62 AFPIRHYVERKGIHFIAQSAEQIDAEAQNITLADGNTVHYDYLMIATGPKLAFENVPG-- 119 Query: 159 EGFAHPKIGSNYSVKTVEKTWKALQDFK----EGNAIFTFPNTPVKCAGAPQKIMYLSEA 214 + P G S+ TV+ +A +++ E I C G + + + Sbjct: 120 ---SDPHEGPVQSIATVDHAERAFAEYQALLREPGPIVIGAMAGASCFGPAYEYAMIVAS 176 Query: 215 YFRKTGKRSKAN-IIFNTSLGAIF-----GVKKYADALQEIIQERNLTVNYKKNLIEVRA 268 +K G R K F TS I GV L + ++E + + +V Sbjct: 177 DLKKRGMRDKIPSFTFITSEPYIGHLGIQGVGDSKGILTKGLKEEGIEAYTNCKVTKVED 236 Query: 269 DKQEAVFENLDKPGET---QVISYEMLHVTPPMSP-PDVLKTSPVADAAGWVDVDKETLQ 324 +K +D+ GET V+ + + P P V + + G+V VD + Sbjct: 237 NKMYVT--QVDEKGETIKEMVLPVKFGMMIPAFKGVPAVAGVEGLCNPGGFVLVD----E 290 Query: 325 HRRYPNVFGIG-----------DCTNLPT--SKTAAAVAAQSGILDRTISVIM---KNQT 368 H+R I + T +PT KT + + I + K + Sbjct: 291 HQRSKKYANIFAAGIAIAIPPVETTPVPTGAPKTGYMIESMVSAAVHNIKADLEGRKGEQ 350 Query: 369 PTKKYDGYTSC 379 ++ Sbjct: 351 TMGTWNAVCFA 361 >3HYW-A nrPDB Length = 430 Score = 274 bits (701), Expect = 5e-74, Method: Composition-based stats. Identities = 67/331 (20%), Positives = 133/331 (40%), Gaps = 35/331 (10%) Query: 58 MAARMKRKVGAENVAIVEPSERHFYQPIWTLVGAGAKQLSSSGRPTASVIPS-GVEWIKA 116 A ++ + + ++ + P + + G ++ P A ++P +E+I Sbjct: 17 TAYNLRNLMPDLKITLISDRPYFGFTPAFPHLAMGWRKFEDISVPLAPLLPKFNIEFINE 76 Query: 117 RVTELNPDKNCIHTDDDEKISYRYLIIALGIQLDYEKIKGLPEGFAHPKIGSNYSVKTVE 176 + ++PD N + T +KI Y YL+IA G +L + A + ++ S+ T E Sbjct: 77 KAESIDPDANTVTTQSGKKIEYDYLVIATGPKLVFG---------AEGQEENSTSICTAE 127 Query: 177 K---TWKALQDFKEGNAIFTFPNTP-VKCAGAPQKIMYLSEAYFRKTGKRSKANIIFNTS 232 T K LQ+ P V C G + + +K G R K + F TS Sbjct: 128 HALETQKKLQELYANPGPVVIGAIPGVSCFGPAYEFALMLHYELKKRGIRYKVPMTFITS 187 Query: 233 LGA-----IFGVKKYADALQEIIQERNLTVNYKKNLIEVRADKQEAVFENLDKPGETQVI 287 + G+ ++++ ERN+ ++ N+ + + ++E+L+ G T + Sbjct: 188 EPYLGHFGVGGIGASKRLVEDLFAERNI--DWIANVAVKAIEPDKVIYEDLN--GNTHEV 243 Query: 288 SYEMLHVTPPMSPPDVLKTSP--VADAAGWVDVDKETLQHRRYPNVFGIGDCTNLP---- 341 + P P+V+ ++ VA+ A + + Q+ Y N+FG+G T +P Sbjct: 244 PAKFTMFMPSFQGPEVVASAGDKVANPANKMVIVNRCFQNPTYKNIFGVGVVTAIPPIEK 303 Query: 342 ------TSKTAAAVAAQSGILDRTISVIMKN 366 KT + + + I ++N Sbjct: 304 TPIPTGVPKTGMMIEQMAMAVAHNIVNDIRN 334 >3H8L-A nrPDB Length = 409 Score = 272 bits (696), Expect = 2e-73, Method: Composition-based stats. Identities = 77/375 (20%), Positives = 152/375 (40%), Gaps = 44/375 (11%) Query: 45 EVLVLGGGSGGITMAARMKRKVGAE-NVAIVEPSERHFYQPIWTLVGAGAKQLSSSGRPT 103 +VLVLGG G +T A +KR VG++ +V ++ S +++P V G + + Sbjct: 3 KVLVLGGRFGALTAAYTLKRLVGSKADVKVINKSRFSYFRPALPHVAIGVRDVDELKVDL 62 Query: 104 ASVIP-SGVEWIKARVTELNPDKNCIH-TDDDEKIS---YRYLIIALGIQLDYEKIKGLP 158 + +P G+++ + V +++ + ++ T D ++ Y Y+I+ +G L E +KG Sbjct: 63 SEALPEKGIQFQEGTVEKIDAKSSMVYYTKPDGSMAEEEYDYVIVGIGAHLATELVKGW- 121 Query: 159 EGFAHPKIGSNYSVKTVEKTWKALQDFKEGNAIF------------------TFPNTPVK 200 + + + ++ K EK L+ F+ GN PN Sbjct: 122 DKYGYSVCEPEFATKLREK----LESFQGGNIAIGSGPFYQGHNPKPKVPENFVPNADSA 177 Query: 201 CAGAPQKIMYLSEAYFRKTGKRSKANIIFNTSLGAIFGVKKYAD-ALQEIIQERNLTVNY 259 C G ++ + YF+K G K ++ + + + + A+ I + + + + Sbjct: 178 CEGPVFEMSLMLHGYFKKKGMLDKVHVTVFSPGEYLSDLSPNSRKAVASIYNQLGIKLVH 237 Query: 260 KKNLIEVRADKQEAVFENLDKPGETQVISYEMLHVTPPMSPPDVLKTS--PVADAAGWVD 317 + E+R E +D+ G T I ++ + PP + LK S + D G++ Sbjct: 238 NFKIKEIRE------HEIVDEKGNT--IPADITILLPPYTGNPALKNSTPDLVDDGGFIP 289 Query: 318 VDKETLQHRRYPNVFGIGDCTNLPTSKTAAAVAAQSGILDRTISVIMKNQTPTKKYDGYT 377 D + +Y NV+ +GD ++ K I + ++ + T KY Sbjct: 290 TDLNMV-SIKYDNVYAVGDANSMTVPKLGYLAVMTGRIAAQHLANRLGVPTKVDKYYPTI 348 Query: 378 SCPL---VTGYNRVI 389 C GY + Sbjct: 349 VCVADNPYEGYAVSV 363 >5NA1-A nrPDB Length = 408 Score = 144 bits (362), Expect = 8e-35, Method: Composition-based stats. Identities = 58/348 (16%), Positives = 127/348 (36%), Gaps = 27/348 (7%) Query: 40 ARNHYEVLVLGGGSGGITMAARMKRKVGAE--NVAIVEPSERHFYQPIWTLVGAGAKQLS 97 A++ +VLVLG G G+ ++++ + E + ++ +E H+ AG Sbjct: 8 AQDRKKVLVLGAGYAGLQTVTKLQKAISTEEAEITLINKNEYHYEATWLHEASAGTLNYE 67 Query: 98 SSGRPTASVIPSG-VEWIKARVTELNPDKNCIHTDDDEKISYRYLIIALGIQLDYEKIKG 156 P SV+ V +++A VT+++ D + T+ + L++ALG + I+G Sbjct: 68 DVLYPVESVLKKDKVNFVQAEVTKIDRDAKKVETNQG-IYDFDILVVALGFVSETFGIEG 126 Query: 157 LPEGFAHPKIGSNYSVKTVEKTWKALQDF------KEGNAIFTFPNTPVKCAGAPQKIMY 210 + + A + + ++ + + ++ Sbjct: 127 MKD-HAFQIENVITARELSRHIEDKFANYAASKEKDDNDLSILVGGAGFTGVEFLGELTD 185 Query: 211 LSEAYFRKTGK-RSKANIIFNTSLGAIFGV--KKYADALQEIIQERNLTVNYKKNLIEVR 267 K G ++K I + + + ++ + +++R + K + Sbjct: 186 RIPELCSKYGVDQNKVKITCVEAAPKMLPMFSEELVNHAVSYLEDRGVEF---KIATPIV 242 Query: 268 ADKQEAVFENLDKPGETQVISYEMLHVTPPMSPPDVLKTSPVADAAGWVDVDKETLQHRR 327 A ++ +D GE Q ++ + +++ S G + V K+ L Sbjct: 243 ACNEKGFVVEVD--GEKQQLNAGTSVWAAGVRGSKLMEESFEGVKRGRI-VTKQDLTING 299 Query: 328 YPNVFGIGDCTNL-------PTSKTAAAVAAQSGILDRTISVIMKNQT 368 Y N+F IGDC+ P TA Q + + I I+ ++ Sbjct: 300 YDNIFVIGDCSAFIPAGEERPLPTTAQIAMQQGESVAKNIKRILNGES 347 >4G74-A nrPDB Length = 502 Score = 79.8 bits (195), Expect = 2e-15, Method: Composition-based stats. Identities = 64/359 (17%), Positives = 122/359 (33%), Gaps = 47/359 (13%) Query: 42 NHYEVLVLGGGSGGITMAARMKRKVGAE--NVAIVEPSERHFYQPIWTLVGAGAKQLSSS 99 + VL+LG G G I+ + + + NV+I+ P + P+ G S Sbjct: 41 DKPNVLILGSGWGAIS----FLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSI 96 Query: 100 GRPTASVIPS---GVEWIKARVTELNPDKNCI--------------------HTDDDEKI 136 P + V + +A T +NPD+N + H + +I Sbjct: 97 IEPIVNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEI 156 Query: 137 SYRYLIIALGIQLDYEKIKGLPEGFAHPKIGSNYSVKTVEKTWKALQD---FKEGNA--- 190 Y YLI A+G + + I G+ + + H S++ L+ +G+ Sbjct: 157 KYDYLISAVGAEPNTFGIPGVTD-YGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERR 215 Query: 191 ---IFTFPNTPVKCAGAPQKIMYLSEAYFRK--TGKRSKANIIFNTSLGAIFGV--KKYA 243 A ++ RK + I +L + + KK + Sbjct: 216 RLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLS 275 Query: 244 DALQEIIQERNLTVNYKKNLIEVRADKQEAVFENLDKPGETQVISYEMLHVTPPMSPPDV 303 Q ++ ++ V+ + + +V + A ++ D + I Y L V Sbjct: 276 SYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPV 335 Query: 304 L----KTSPVADAAGWVDVDKETLQHRRYPNVFGIGDCTNLPTSKTAAAVAAQSGILDR 358 + K P +++ + LQ + N+F IGD TA ++ L + Sbjct: 336 ITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAK 394 >3KLJ-A nrPDB Length = 385 Score = 64.4 bits (155), Expect = 9e-11, Method: Composition-based stats. Identities = 27/124 (21%), Positives = 52/124 (41%), Gaps = 7/124 (5%) Query: 43 HYEVLVLGGGSGGITMAARMKRKVGA-ENVAIVEPSERH-FYQPIWTLVGAGAKQLSSSG 100 ++L+LG G G + A K +G +++ ++ + +Y+P + A K + Sbjct: 9 STKILILGAGPAGFSAA---KAALGKCDDITMINSEKYLPYYRPRLNEIIAKNKSIDDIL 65 Query: 101 RPTASVIPSG-VEWIKAR-VTELNPDKNCIHTDDDEKISYRYLIIALGIQLDYEKIKGLP 158 ++ I + T ++P+ + EKI Y LIIA G + K+ Sbjct: 66 IKKNDWYEKNNIKVITSEFATSIDPNNKLVTLKSGEKIKYEKLIIASGSIANKIKVPHAD 125 Query: 159 EGFA 162 E F+ Sbjct: 126 EIFS 129 >1NHQ-A nrPDB Length = 447 Score = 59.8 bits (143), Expect = 3e-09, Method: Composition-based stats. Identities = 69/364 (18%), Positives = 125/364 (34%), Gaps = 42/364 (11%) Query: 45 EVLVLGGGSGGITMAARMKRKVGAENVAIVEPSERHFYQP--IWTLVGAGAKQLSSSGRP 102 +V+VLG GG + + E + + + + K ++S Sbjct: 2 KVIVLGSSHGGYEAVEELLNLHPDAEIQWYEKGDFISFLSSGMQLYLEGKVKDVNSVRYM 61 Query: 103 TASVIPS-GVE-WIKARVTELNPDKNCIHTDD-----DEKISYRYLIIALGIQLDYEKIK 155 T + S GV + +T + P ++ + D + +Y LII+ G I Sbjct: 62 TGEKMESRGVNVFSNTEITAIQPKEHQVTVKDLVSGEERVENYDKLIISPGAVPFELDIP 121 Query: 156 GLPEGFAHPKIGSNYSVKTVEKTWKALQDFKEGNAIFTFPNTPVKCAGAPQKIMYLSEAY 215 G + G +++K +KT D + N + G+ I + Sbjct: 122 GKDLDNIYLMRGRQWAIKLKQKTV----DPEVNNVVVI---------GSGY-IGIEAAEA 167 Query: 216 FRKTGKRSKANIIFNTSLGAIFGVKKYADALQEIIQERNLTVNYKKNLIEVRADKQEAVF 275 F K GK+ I + LG ++ K++ D L E ++ N+T+ R + V Sbjct: 168 FAKAGKKVTVIDILDRPLG-VYLDKEFTDVLTEEMEANNITIAT--GETVERYEGDGRVQ 224 Query: 276 ENLDKPGETQVISYEMLHVTPPMSPPDV-LKTSPVADAAGWVDVDKETLQHRRYPNVFGI 334 + + +++ V + P LK + G + D+ P+VF + Sbjct: 225 KVVTDKN---AYDADLVVVAVGVRPNTAWLKGTLELHPNGLIKTDEYMRTSE--PDVFAV 279 Query: 335 GDCTNLPTSKTAAAVAAQSGILDR--TISVIMKNQTPTKKYDGYTSCPLVTGYNRVILAE 392 GD T + + V R + + P K + G LA Sbjct: 280 GDATLIKYNPADTEVNIALATNARKQGRFAVKNLEEPVKPFPGV--------QGSSGLAV 331 Query: 393 FDYK 396 FDYK Sbjct: 332 FDYK 335 >3IWA-A nrPDB Length = 472 Score = 56.7 bits (135), Expect = 2e-08, Method: Composition-based stats. Identities = 49/322 (15%), Positives = 112/322 (34%), Gaps = 50/322 (15%) Query: 44 YEVLVLGGGSGGITMAARMKRKVGAENVAIVEPSERHFY--QPIWTLVGAGAKQLSSS-G 100 V+V+G + G A R KR +V +++ + R Y I V + S Sbjct: 4 KHVVVIGAVALGPKAACRFKRLDPEAHVTMIDQASRISYGGCGIPYYVSGEVSNIESLQA 63 Query: 101 RPTASVIP-------SGVE-WIKARVTELNPDKNCIH-----TDDDEKISYRYLIIALGI 147 P V VE ++ R ++ + + T + + Y L++ALG Sbjct: 64 TPYNVVRDPEFFRINKDVEALVETRAHAIDRAAHTVEIENLRTGERRTLKYDKLVLALGS 123 Query: 148 QLDYEKIKGLPEGFAHPK------IGSNYSVKTVEKTWKALQDFKEGNAIFTFPNTPVKC 201 + + ++G+ P +++ E + G I Sbjct: 124 KANRPPVEGMDLAGVTPVTNLDEAEFVQHAISAGEVSK---AVIVGGGFIGL-------- 172 Query: 202 AGAPQKIMYLSEAYFRKTGKRSKANIIFNTSLGAIFGVKKYADALQEIIQERNLTVNYKK 261 ++ + G + + + + F K + L+ +++ ++ V+ + Sbjct: 173 -----EMAVSLADMW---GIDTTVVELADQIMPG-FTSKSLSQMLRHDLEKNDVVVHTGE 223 Query: 262 NLIEVRADKQEAVFENLDKPGETQVISYEMLHVTPPMSPP-DVLKTSPV-ADAAGWVDVD 319 ++ + + + DK + +++ + +SP + + + + D G + VD Sbjct: 224 KVVRLEGENGKVARVITDKR----TLDADLVILAAGVSPNTQLARDAGLELDPRGAIIVD 279 Query: 320 KETLQHRRYPNVFGIGDCTNLP 341 P++F GDC +P Sbjct: 280 TRMRTSD--PDIFAGGDCVTIP 299 >3CGD-A nrPDB Length = 480 Score = 55.9 bits (133), Expect = 3e-08, Method: Composition-based stats. Identities = 58/357 (16%), Positives = 125/357 (35%), Gaps = 50/357 (14%) Query: 23 GTQQVGPLQLHTGASHAARNHYEVLVLGGGSGGITMAARMKRKVGAENVAIVEPSE-RHF 81 G QQ+G L+ +++GG + G++ A ++ R NV +E E + Sbjct: 17 GGQQMGR-TLYDDDDKDRWGSMNYVIIGGDAAGMSAAMQIVRNDENANVVTLEKGEIYSY 75 Query: 82 YQPIWTLVGAGAKQLSS--SGRPTASVIPS-GVEW-IKARVTELNPDKNCIH-----TDD 132 Q V +GA + R + G++ ++ VT+++ +K ++ T D Sbjct: 76 AQCGLPYVISGAIASTEKLIARNVKTFRDKYGIDAKVRHEVTKVDTEKKIVYAEHTKTKD 135 Query: 133 DEKISYRYLIIALGIQLDYEKIKGLPEGFAHPKIGSNYSVKTVEKTWKALQDFKEGNAIF 192 + SY L+IA G++ + +G H + E+ K L+ K + Sbjct: 136 VFEFSYDRLLIATGVRPVMPEWEGRDLQGVHLLKTIPDA----ERILKTLETNKVEDVTI 191 Query: 193 TFPNTPVKCAGAPQKIMYLSEAYFRKTGKRSKANIIFNTSLGAIFGVKKYADALQEIIQE 252 I F + GK K +I A+ + + + Sbjct: 192 IGGGA----------IGLEMAETFVELGK--KVRMIERNDHIGTIYDGDMAEYIYKEADK 239 Query: 253 RNLTVNYKKNLIEVRADKQEAVFENLDKPGETQVISYEMLHVTPPMSPPD--VLKTSPVA 310 ++ + +N+ + +++ E G +++ V+ + P + T+ Sbjct: 240 HHIEILTNENVKAFKGNERVEAVET--DKG---TYKADLVLVSVGVKPNTDFLEGTNIRT 294 Query: 311 DAAGWVDVDKETLQHRRYPNVFGIGDCTN-----------LPTSKTAAAVAAQSGIL 356 + G ++V+ + + +V+ GDC +P Q + Sbjct: 295 NHKGAIEVNAYMQTNVQ--DVYAAGDCATHYHVIKEIHDHIPI---GTTANKQGRLA 346 >1EBD-A nrPDB Length = 455 Score = 55.5 bits (132), Expect = 4e-08, Method: Composition-based stats. Identities = 50/312 (16%), Positives = 112/312 (35%), Gaps = 39/312 (12%) Query: 56 ITMAARMKRKVGAENVAIVEPSERHFYQPIWTLVGAGAKQLSSSGRPTASVIPSG-VEWI 114 I+ + R ++ +E + I + + + + K+L+ ++ VE + Sbjct: 53 ISASHRYEQAKHSEEMGIKAENVTIDFAKVQEWKASVVKKLTG---GVEGLLKGNKVEIV 109 Query: 115 KARVTELNPDKNCIHTDDDE-KISYRYLIIALGIQLDYEKIKGLPEGFAHPKIGSNYSVK 173 K ++ + + D +++ IIA G + I+ F++ + S ++ Sbjct: 110 KGEAYFVDANTVRVVNGDSAQTYTFKNAIIATGSR----PIELPNFKFSNRILDSTGALN 165 Query: 174 TVEKTWKALQDFKEGNAIFTFPNTPVKCAGAPQKIMYLSEAYFRKTGKRSKANIIFNTSL 233 E K+L G I T G +K I+ Sbjct: 166 LGE-VPKSLVVI-GGGYIGIELGTAYANFG-------------------TKVTILEGAGE 204 Query: 234 GAIFGVKKYADALQEIIQERNLTVNYKKNLIEVRADKQEAVFENLDKPGETQVISYEMLH 293 K+ A +++ ++++ + V L + ++++ V + GET+ I + + Sbjct: 205 ILSGFEKQMAAIIKKRLKKKGVEVVTN-ALAKGAEEREDGVTVTYEANGETKTIDADYVL 263 Query: 294 VTPPMSPPD----VLKTSPVADAAGWVDVDKETLQHRRYPNVFGIGDCTNLPTSKTAAAV 349 VT P + + G ++VD++ PN+F IGD +P A Sbjct: 264 VTVGRRPNTDELGLEQIGIKMTNRGLIEVDQQCRTSV--PNIFAIGD--IVPGPALAHKA 319 Query: 350 AAQSGILDRTIS 361 + + + I+ Sbjct: 320 SYEGKVAAEAIA 331 >5JWC-A nrPDB Length = 521 Score = 55.5 bits (132), Expect = 4e-08, Method: Composition-based stats. Identities = 58/404 (14%), Positives = 128/404 (31%), Gaps = 75/404 (18%) Query: 37 SHAARNHYEVLVLGGGSGGITMAARMKRKVGAENVAIVEPSERHFYQPIWTLVGAGAKQL 96 + ++++LG G GG + +V ++ P + P+ + +G + Sbjct: 22 NKDIERKEKIIILGSGWGGFN--FLLNIDFKKYDVTLISPRNYFTFTPLLPCLCSGTLSV 79 Query: 97 SSSGRPTASVIPS--------------GVEWIKARVTELNPDKNCIHTDDDEKISYRYLI 142 + + + V + + ++ + N + K+ Y YLI Sbjct: 80 NVCTESIRNFLRKKNGYCGNYLQLECTDVFYEDKYINCIDIENNKV------KLFYDYLI 133 Query: 143 IALGIQLDYEKIKGLPEGFAHPKIGSNYSVKTVEKTWKALQDFKEGNA----------IF 192 IA+G + + I G+ + +A+ + ++K +K L+ N + Sbjct: 134 IAVGAKTNTFNINGV-DKYAYFVKDIDDALKIRKKFLDILEKCTLPNISNEEKKKMLHVA 192 Query: 193 TFPNTPVKCAGAPQKIMYLSEAYFRKTGKRSKANIIFNTSLGAIFGV----KKYADALQE 248 P + + K I + G + + +D +E Sbjct: 193 VVGGGPTGVEVTA-EFADFINKEVKINYKDIFNFISISIIEGGNNLLPTFTQNISDFTKE 251 Query: 249 IIQERNLTVNYKKNLIEVRADKQEAVFENLDKPGETQVISY----------------EML 292 N+ V +I+V DK ++ E + +SY + L Sbjct: 252 NFHNLNINVLTNYYVIDV--DKHSFHIQSSLNKNEKKKLSYGLLIWASGLAQTTLIQKFL 309 Query: 293 HVTPPMSPPDVLKTSPVADAAGWVDVDKETLQHRRYPNVFGIGDCTNLPTSKTAAAVAAQ 352 P + +LK G + + N++ IGDC + K + Sbjct: 310 KTIPVQANNAILKVDEKLRVIG-IPSN----------NIYAIGDCKKI-QPKLLHEHTNE 357 Query: 353 SGILDRTISVIMKNQTPTKKYDGYTSCPLVTGYNRVILAEFDYK 396 I I+ T + L + ++ ++++DY+ Sbjct: 358 -------IIKILTGNKLTSEALKLKQSELTKTFPQLSISKWDYE 394 >1XHC-A nrPDB Length = 367 Score = 55.5 bits (132), Expect = 4e-08, Method: Composition-based stats. Identities = 46/328 (14%), Positives = 124/328 (37%), Gaps = 45/328 (13%) Query: 45 EVLVLGGGSGGITMAARMKRKVGAENVAIVEPSER-HFYQPIWTLVGAGAKQLSSS-GRP 102 +V+++G G GG +A ++ + V +++ ++ +P+ + AG + Sbjct: 10 KVVIVGNGPGGFELAKQLSQ---TYEVTVIDKEPVPYYSKPMLSHYIAGFIPRNRLFPYS 66 Query: 103 TASVIPSGVEW-IKARVTELNPDKNCIHTDDDEKISYRYLIIALGIQLDYEKIKGLPEGF 161 G+E + ++ + + T+ ++ Y L++A G + +IKG Sbjct: 67 LDWYRKRGIEIRLAEEAKLIDRGRKVVITEKG-EVPYDTLVLATGARAREPQIKG----- 120 Query: 162 AHPKIGSNYSVKTVEKTWKALQDFKEGNAIFTFPNTPVKCAGAPQKIMYLSEAYFRKTGK 221 +++T+ + + + I + G Sbjct: 121 ----KEYLLTLRTIFDADRIKESIENSGEAIIIGGG---------FIGLELAGNLAEAGY 167 Query: 222 RSKANIIFNTSLGAIFGVKKYADALQEIIQERNLTVNYKKNLIEVRADKQEAVFENLDKP 281 K + + + ++ ++ ++++++E + L+E A+++ + + Sbjct: 168 HVK---LIHRGAMFLGLDEELSNMIKDMLEETGVKFFLNSELLE--ANEEGVLTNSGFIE 222 Query: 282 GETQVISYEMLHVTPPMSPPDVLKTSPVADAAGWVDVDKETLQHRRYPNVFGIGDCT--N 339 G+ ++ + + + P + D+ + S + G + +D +V+ IGDC + Sbjct: 223 GKVKICA---IGIVPNV---DLARRSGIHTGRG-ILIDDNFRTSA--KDVYAIGDCAEYS 273 Query: 340 LPTSKTAAAVAAQSGILDRTISVIMKNQ 367 + TA A Q+ +L I+K + Sbjct: 274 GIIAGTAKAAMEQARVLAD----ILKGE 297 >3FG2-P nrPDB Length = 404 Score = 55.2 bits (131), Expect = 6e-08, Method: Composition-based stats. Identities = 53/339 (15%), Positives = 115/339 (33%), Gaps = 33/339 (9%) Query: 46 VLVLGGGSGGITMAARMKRKVGAENVAIVEPSERHFYQ--PIWT--LVGAGAKQLSSSGR 101 VL+ G G G +A +++ +A++ + YQ P+ L G S R Sbjct: 4 VLIAGAGHAGFQVAVSLRQAKYPGRIALINDEKHLPYQRPPLSKAYLKSGGDPN-SLMFR 62 Query: 102 PTASVIPSGVEWIKARVTELNPDKNCIHTDDDEKISYRYLIIALGIQLDYEKIKGLPEGF 161 P +E I R+ ++ + + I Y +L++A G + + Sbjct: 63 PEKFFQDQAIELISDRMVSIDREGRKLLLASGTAIEYGHLVLATGARNRMLDVP------ 116 Query: 162 AHPKIGSNYSVKTVEKTWKALQDFKEGNAIFTFPNTPVKCAGAPQKIMYLSEAYFRKTGK 221 + + ++T++++ Q + + + A E + Sbjct: 117 -NASLPDVLYLRTLDESEVLRQRMPDKKHVVVIGAGFIGLEFAATARAKGLEVDVVELAP 175 Query: 222 RSKANIIFNTSLGAIFGVKKYADALQEIIQERNLTVNYKKNLIEVRADKQEAVFENLDKP 281 R A ++ + + + + ++Y E+ A+ L Sbjct: 176 RVMARVV----------TPEISSYFHDRHSGAGIRMHYGVRATEIAAEGDRVTGVVL-SD 224 Query: 282 GETQVISYEMLHVTPPMSPPDVLKTSPVADAAGWVDVDKETLQHRRYPNVFGIGDCTNLP 341 G T + +++ V + P + + A + VD++ L P++ IGDC Sbjct: 225 GNT--LPCDLVVVGVGVIPNVEIAAAAGLPTAAGIIVDQQLLTSD--PHISAIGDCALFE 280 Query: 342 TSKTAAAVAAQS----GILDRTISVIMKNQTPTKKYDGY 376 + + + +S R ++ + K YDGY Sbjct: 281 SVRFGETMRVESVQNATDQARCVAARLTGD--AKPYDGY 317 >3LXD-A nrPDB Length = 415 Score = 53.2 bits (126), Expect = 2e-07, Method: Composition-based stats. Identities = 63/314 (20%), Positives = 105/314 (33%), Gaps = 37/314 (11%) Query: 36 ASHAARNHYEVLVLGGGSGGITMAARMKRKVGAENVAIV--EPSERHFYQPIWTLVGAGA 93 AS +V+++G G GG A +++ V ++ EP + P+ A Sbjct: 2 ASEVQAERADVVIVGAGHGGAQAAIALRQNGFEGRVLVIGREPEIPYERPPLSKEYLARE 61 Query: 94 KQLSSS-GRPTASVIPSGVEW-IKARVTELNPDKNCIHTDDDEKISYRYLIIALGIQLDY 151 K RP VE + A V L+P + + D I Y LI A G Sbjct: 62 KTFERICIRPAQFWEDKAVEMKLGAEVVSLDPAAHTVKLGDGSAIEYGKLIWATGGDPRR 121 Query: 152 EKIKGLPEGFAHPKIGSNYSVKTVEKTWKALQDFKEG--NAIFTFPNTPVKCAGAPQKIM 209 G + ++V+T E + + + G NA+ G I Sbjct: 122 LSCVG-------ADLAGVHAVRTKEDADRLMAELDAGAKNAVVI---------GGGY-IG 164 Query: 210 YLSEAYFRKTGKRSKANIIFNTSLGAIFGVKKYADALQEIIQER----NLTVNYKKNLIE 265 + A K G N+ +L + + +AL E Q + + + Sbjct: 165 LEAAAVLTKFG----VNVTLLEALPRVLA-RVAGEALSEFYQAEHRAHGVDLRTGAAMDC 219 Query: 266 VRADKQEAVFENLDKPGETQVISYEMLHVTPPMSPPDVLKTSPVADAAGWVDVDKETLQH 325 + D + + VI +++ V + P S A VDVD+ Sbjct: 220 IEGDGTKVTGVRMQDGS---VIPADIVIVGIGIVPCVGALISAGASGGNGVDVDEFCRTS 276 Query: 326 RRYPNVFGIGDCTN 339 +V+ IGDC Sbjct: 277 LT--DVYAIGDCAA 288 >2BC1-A nrPDB Length = 490 Score = 51.3 bits (121), Expect = 8e-07, Method: Composition-based stats. Identities = 63/334 (18%), Positives = 109/334 (32%), Gaps = 36/334 (10%) Query: 23 GTQQVGPLQLHTGASHAARNHYEVLVLGGGSGGITMAARMKRKVG-AENVAIVEPSERHF 81 G QQ+G L+ V+V G G M G A + + + + Sbjct: 17 GGQQMGR-TLYDDDDKDRWGSKIVVV-GANHAGTACIKTMLTNYGDANEIVVFDQNSNIS 74 Query: 82 YQPIWTLVGAGAK------QLSSSGRPTASVIPSGVEWIKARVTELNPDKNCIHTDDDEK 135 + + G + S S+ ++++ V ++ D + D K Sbjct: 75 FLGSGMALWIGEQIAGPEGLFYSDKEELESLGAK--VYMESPVQSIDYDAKTVTALVDGK 132 Query: 136 IS---YRYLIIALGIQLDYEKIKGLPEGFAHPKIGSNYSVKTVEKTWKALQDFKEGNAIF 192 Y LI A G Q IKG A K GS T+E + +A Sbjct: 133 NHVETYDKLIFATGSQPILPPIKG-----AEIKEGSLEFEATLENL--QFVKLYQNSADV 185 Query: 193 TFPNTP-----VKCAGAPQKIMYLSEAYFRKTGKRSKANIIFNTSLGAIFGVKKYADALQ 247 V GA I F++ GK + +T L + + D + Sbjct: 186 IAKLENKDIKRVAVVGAGY-IGVELAEAFQRKGKEVVLIDVVDTCLAGYY-DRDLTDLMA 243 Query: 248 EIIQERNLTVNYKKNLIEVRADKQEAVFENLDKPGETQVISYEMLHVTPPMSPPDVLKTS 307 + ++E + + + + + EV + V + + E +M+ + P L Sbjct: 244 KNMEEHGIQLAFGETVKEVAGN--GKVEKIITDKNE---YDVDMVILAVGFRPNTTLGNG 298 Query: 308 PV-ADAAGWVDVDKETLQHRRYPNVFGIGDCTNL 340 + G V+K Q P V+ IGDC + Sbjct: 299 KIDLFRNGAFLVNKR--QETSIPGVYAIGDCATI 330 >5MJK-A nrPDB Length = 327 Score = 51.3 bits (121), Expect = 9e-07, Method: Composition-based stats. Identities = 58/313 (18%), Positives = 96/313 (30%), Gaps = 43/313 (13%) Query: 36 ASHAARNHYEVLVLGGGSGGITMA-----ARMKRKVGAENVAIVEPSERHFYQ-PIWTLV 89 SH Y+V+++G G G+T A + MK + V + + + Sbjct: 17 GSHMTEKKYDVVIIGSGPAGMTAAMYTARSEMKTLLLERGVPGGQMNNTAEIENYPGYET 76 Query: 90 GAGAKQLSSSGRPTASVIPSGVEWIKARVTELN--PDKNCIHTDDDEKISYRYLIIALGI 147 G + P + GVE VT + D I T+DDE I+ + +IIA G Sbjct: 77 IMGPELSMKMAEPLEGL---GVENAYGFVTGIEDHGDYKKIITEDDEFIT-KSIIIATGA 132 Query: 148 QLDYEKIKGLPEGFAHPKIGSNYSVKTVEKTWKALQDFKEGNAIFTFPNTPVKCAGAPQK 207 +I G E A S +V F I A Sbjct: 133 NHRKLEIPGEEEYGARGV--SYCAVCDG--------AFFRNQEILVIGGGDSAVEEALYL 182 Query: 208 IMYLSEAYFRKTGKRSKANIIFNTSLGAIFGVKKYADALQEIIQERNLTVNYKKNLIEVR 267 + R K Q +E + + +E++ Sbjct: 183 TRFGQSVTIMHR--RDKLRAQEIIQ--------------QRAFKEEKINFIWDSVPMEIK 226 Query: 268 AD---KQEAVFENLDKPGETQVISYEMLHVTPPMSPPDVLKTSPVADAAGWVDVDKETLQ 324 D Q V++N+ T+ + + + + D AGW+ D Sbjct: 227 GDDKKIQSVVYKNVKTGEVTEKAFGGIFIYVGLDPVAEFVSDLGITDEAGWIITDDHMRT 286 Query: 325 HRRYPNVFGIGDC 337 + P +F +GD Sbjct: 287 NI--PGIFAVGDV 297 >2CDU-A nrPDB Length = 452 Score = 50.9 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 62/364 (17%), Positives = 123/364 (33%), Gaps = 43/364 (11%) Query: 45 EVLVLGGGSGGITMAARMKRKVGAENVAIVEPSERHFY--QPIWTLVGAGAKQLSSSGRP 102 +V+V+G G + +V E ++ + I +G K G Sbjct: 2 KVIVVGCTHAGTFAVKQTIADHPDADVTAYEMNDNISFLSCGIALYLGKEIKNNDPRGLF 61 Query: 103 TASV-----IPSGVEWIKARVTELNPDKNCIH-----TDDDEKISYRYLIIALGIQLDYE 152 +S + + V+ VT ++P+ I T++++ +Y LI+ G + Sbjct: 62 YSSPEELSNLGANVQMRHQ-VTNVDPETKTIKVKDLITNEEKTEAYDKLIMTTGSKPTVP 120 Query: 153 KIKGLPEGFAHPKIGSNYSVKTVEKTWKALQDFKEGNAIFTFPNTPVKCAGAPQKIMYLS 212 I G+ + N + K E+ KA I G+ L+ Sbjct: 121 PIPGIDSSRVYLCKNYNDAKKLFEEAPKA-------KTITII--------GSGYIGAELA 165 Query: 213 EAYFRKTGKRSKANIIF-NTSLGAIFGVKKYADALQEIIQERNLTVNYKKNLIEVRADKQ 271 EAY + + N+I + + + K++ D L + + + + + Sbjct: 166 EAY---SNQNYNVNLIDGHERVLYKYFDKEFTDILAKDYEAHGVNLVLGSKVAAFEEVDD 222 Query: 272 EAVFENLDKPGETQVISYEMLHVTPPMSPPDVLKTSPVAD-AAGWVDVDKETLQHRRYPN 330 E + + LD I ++ + P L VA G + D+ R + Sbjct: 223 EIITKTLDGK----EIKSDIAILCIGFRPNTELLKGKVAMLDNGAIITDEYMHSSNR--D 276 Query: 331 VFGIGDCTNL---PTSKTAAAVAAQSGILDRTISVIMKNQTPTKKYDGYTSCPLVTGYNR 387 +F GD + PT+ A A + + + + + K G S + Y R Sbjct: 277 IFAAGDSAAVHYNPTNSNAYIPLATNAVRQGRLVGLNLTEDKVKD-MGTQSSSGLKLYGR 335 Query: 388 VILA 391 ++ Sbjct: 336 TYVS 339 >2YVG-A nrPDB Length = 408 Score = 49.8 bits (117), Expect = 3e-06, Method: Composition-based stats. Identities = 43/305 (14%), Positives = 100/305 (32%), Gaps = 35/305 (11%) Query: 46 VLVLGGGSGGITMAARMKRKVGAENVAIV-EPSERHFYQPIWTLVGAGAKQLSSSGRPTA 104 V+VLG G ++ A +++ + +V + +ER + +P + Sbjct: 10 VVVLGAGLASVSFVAELRQAGYQGLITVVGDEAERPYDRPPLSKDFMAHGDAEKIRLDCK 69 Query: 105 SVIPSGVEWIKA-RVTELNPDKNCIHTDDDEKISYRYLIIALGIQLDYEKIKGLPEGFAH 163 VEW+ +P + + D + Y L++A G + LP Sbjct: 70 --RAPEVEWLLGVTAQSFDPQAHTVALSDGRTLPYGTLVLATGA-----APRALPTLQGA 122 Query: 164 PKIGSNYSVKTVEKTWKALQDFKEGNAIFTFPNTPVKCAGAPQKIMYLSEAYFRKTGKRS 223 ++++T+E + + + + + A +T R Sbjct: 123 TM--PVHTLRTLEDARRIQAGLRPQSRLLIVGGGVIGLELAATARTAGVHVSLVETQPR- 179 Query: 224 KANIIFNTSLGAIFGVKKYADALQEIIQERNLTVNYKKNLIEVRADKQEAVFENLDKPGE 283 L + AD + + + + +++++ + V D Sbjct: 180 ---------LMSRAAPATLADFVARYHAAQGVDLRFERSVT----GSVDGVVLLDDGT-- 224 Query: 284 TQVISYEMLHV-TPPMSPPDVLKTSPV-ADAAGWVDVDKETLQHRRYPNVFGIGDCTNLP 341 I+ +M+ V ++ + + + + D +VD T P+V+ +GD T Sbjct: 225 --RIAADMVVVGIGVLANDALARAAGLACDDGIFVDAYGRT----TCPDVYALGDVTRQR 278 Query: 342 TSKTA 346 + Sbjct: 279 NPLSG 283 >5ER0-A nrPDB Length = 518 Score = 48.6 bits (114), Expect = 5e-06, Method: Composition-based stats. Identities = 63/372 (16%), Positives = 120/372 (32%), Gaps = 40/372 (10%) Query: 34 TGASHAARNHYEVLVLGGGSGGITMAARMKRKVGAENVAIVEPSERHFY--QPIWTLVGA 91 + A +V V+G G ++ + V + E ++ + I +G Sbjct: 41 DDKAMADIGSMKVTVVGCTHAGTFAIKQILAEHPDAEVTVYERNDVISFLSCGIALYLGG 100 Query: 92 GAKQLSSSGRPTASVIPS-GVEWI-KARVTELNPDKNCIHTDD-----DEKISYRYLIIA 144 + + G V ++PD+ + +D SY L++ Sbjct: 101 KVADPQGLFYSSPEELQKLGANVQMNHNVLAIDPDQKTVTVEDLTNHAQTTESYDKLVMT 160 Query: 145 LGIQLDYEKIKGLPEGFAHPKIGSNYSVKTVEKTWKALQDFKEGNAIFTFPNTPVKCAGA 204 G KI G+ K+ N++ ++D KE I GA Sbjct: 161 SGSWPIVPKIPGIDSDRV--KLCKNWA-----HAQALIEDAKEAKRITVI--------GA 205 Query: 205 PQKIMYLSEAYFRKTGKRSKANIIFNTSLGAIFGVKKYADALQEIIQERNLTVNYKKNLI 264 L+EAY I + + + D +++ ++ + + + + Sbjct: 206 GYIGAELAEAYSTTGH--DVTLIDAMARVMPKYFDADFTDVIEQDYRDHGVQLALGETVE 263 Query: 265 EVRADKQEAVFENLDKPGETQVISYEMLHVTPPMSPP-DVLKTSPVADAAGWVDVDKETL 323 + ET ++ + P D+LK G + D Sbjct: 264 SFTDSATGLTIKTDKNSYET-----DLAILCIGFRPNTDLLKGKVDMAPNGAIITDDYMR 318 Query: 324 QHRRYPNVFGIGDCTNL---PTSKTAAAVAAQSGILDRTISVIMKN-QTPTKKYDGYTSC 379 P++F GD + PT + A A + + R ++ KN PT KY G S Sbjct: 319 SSN--PDIFAAGDSAAVHYNPTHQNAYIPLATNAV--RQGILVGKNLVKPTVKYMGTQSS 374 Query: 380 PLVTGYNRVILA 391 + Y+R I++ Sbjct: 375 SGLALYDRTIVS 386 >3F8P-A nrPDB Length = 323 Score = 46.3 bits (108), Expect = 2e-05, Method: Composition-based stats. Identities = 42/270 (15%), Positives = 90/270 (33%), Gaps = 36/270 (13%) Query: 97 SSSGRPTASVIPSGVEWIKARVTELN--PDKNCIHTDDDEKISYRYLIIALGIQLDYEKI 154 + V + V ++ D+ + T + +I+ +G++ + Sbjct: 71 DMIKVFNKHIEKYEVPVLLDIVEKIENRGDEFVVKTKRKGEFKADSVILGIGVKRRKLGV 130 Query: 155 KGLPEGFAHPKIGSNYSVKTVEKTWKALQDFKEGNAIFTFPNTPVKCAGAPQKIMYLSEA 214 G ++ + + + + GA Y ++ Sbjct: 131 PG----------EQEFAGRGISYCSVCDAPLFKNRVVAVIGGGDSALEGAEILSSYSTKV 180 Query: 215 YFRKTGKRSKANIIFNTSLGAIFGVKKYADALQEIIQERNLTVNYKKNLIEVRADK--QE 272 Y KA I+ ++ + ++ N+ + E++ DK ++ Sbjct: 181 YLIHRRDTFKAQPIY----------------VETVKKKPNVEFVLNSVVKEIKGDKVVKQ 224 Query: 273 AVFENLDKPGETQVISYEMLHVTPPMSPP-DVLKTSPV-ADAAGWVDVDKETLQHRRYPN 330 V ENL K GE + ++ + + PP D K++ + D G++ VD+ P Sbjct: 225 VVVENL-KTGEIKELNVNGVFIEIGFDPPTDFAKSNGIETDTNGYIKVDEWMRTSV--PG 281 Query: 331 VFGIGDCTNLPTS-KTAAAVAAQSGILDRT 359 VF GDCT+ + AQ + + Sbjct: 282 VFAAGDCTSAWLGFRQVITAVAQGAVAATS 311 >1Q1R-A nrPDB Length = 431 Score = 46.3 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 22/105 (20%), Positives = 43/105 (40%), Gaps = 4/105 (3%) Query: 46 VLVLGGGSGGITMAARMKRKVGAENVAIVEPSER--HFYQPIWTLVGAGAKQLSSS-GRP 102 V+++G G G+ +A ++ N+ +V + H P+ AG S R Sbjct: 7 VVIVGTGLAGVEVAFGLRASGWEGNIRLVGDATVIPHHLPPLSKAYLAGKATAESLYLRT 66 Query: 103 TASVIPSGVEWIKAR-VTELNPDKNCIHTDDDEKISYRYLIIALG 146 + ++ + VT +N D+ + D + Y L++A G Sbjct: 67 PDAYAAQNIQLLGGTQVTAINRDRQQVILSDGRALDYDRLVLATG 111 >3OC4-A nrPDB Length = 452 Score = 45.9 bits (107), Expect = 3e-05, Method: Composition-based stats. Identities = 52/348 (14%), Positives = 119/348 (34%), Gaps = 42/348 (12%) Query: 43 HYEVLVLGGGSGGITMAARMKRKVGAENVAIVEPSERHFY-----QPIWTLVGAGAKQLS 97 +++++G GI+ A ++K +++++ Y + +L Sbjct: 2 SLKIVIIGASFAGISAAIASRKKYPQAEISLIDKQATVGYLSGGLSAYFNHTI---NELH 58 Query: 98 SSGRPTAS-VIPSGVEWI-KARVTELNPDKNCIHTDDDEK---ISYRYLIIALGIQLDYE 152 + T + ++ + V ++ + I E+ SY LI+A G Sbjct: 59 EARYITEEELRRQKIQLLLNREVVAMDVENQLIAWTRKEEQQWYSYDKLILATGASQFST 118 Query: 153 KIKGLPEGFAHPKIGSNYSVKTVEKTWKALQDFKEGNAIFTFPNTPVKCAGAPQKIMYLS 212 +I+G + K + A+ + + P+ + Sbjct: 119 QIRG-------SQTEKLLKYKFLSGALAAVPLLENSQTVAVIGAGPIG----------ME 161 Query: 213 EAYFRKTGKRSKANIIFNTSLGAIFGVKKYADALQEIIQERNLTVNYKKNLIEVRADKQE 272 F K++ +L + K+ +Q+ ++++ + ++++ ++ + Sbjct: 162 AIDFLVKMKKTVHVFESLENLLPKYFDKEMVAEVQKSLEKQAVIFHFEETVLGIEETANG 221 Query: 273 AVFENLDKPGETQVISYEMLHVTPPMSPPDVLKTSPVADAAGWVDVDKETLQHRRYPNVF 332 V E + Q IS + + P + LQ PNVF Sbjct: 222 IVLETSE-----QEISCDSGIFALNLHPQLAYLDKKIQRNLDQTIAVDAYLQTSV-PNVF 275 Query: 333 GIGDCTNL---PTSKTAAAVAAQSGILDRTISVIMKN-QTPTKKYDGY 376 IGDC ++ P ++T A + + RT V+ N + T ++ G Sbjct: 276 AIGDCISVMNEPVAETFYAPLVNNAV--RTGLVVANNLEEKTHRFIGS 321 >4EMJ-A nrPDB Length = 410 Score = 45.9 bits (107), Expect = 3e-05, Method: Composition-based stats. Identities = 42/301 (13%), Positives = 97/301 (32%), Gaps = 26/301 (8%) Query: 45 EVLVLGGGSGGITMAARMKRKVGAENVAIV--EPSERHFYQPIWTLVGAGAKQLSSSGRP 102 V ++G G GG T A ++ + ++++ EP + + V G+ + Sbjct: 4 HVAIIGNGVGGFTTAQALRAEGFEGRISLIGDEPHLPYDRPSLSKAVLDGSLERPPILAE 63 Query: 103 TASVIPSGVEWIKA-RVTELNPDKNCIHTDDDEKISYRYLIIALGIQLDYEKIKGLPEGF 161 + ++ + VT L+ I DD +S ++IA G + + G Sbjct: 64 ADWYGEARIDMLTGPEVTALDVQTRTISLDDGTTLSADAIVIATGSRARTMALPG----- 118 Query: 162 AHPKIGSNYSVKTVEKTWKALQDFKEGNAIFTFPNTPVKCAGAPQKIMYLSEAYFRKTGK 221 ++ +++T + + + C RK G Sbjct: 119 --SQLPGVVTLRTYGDVQVLRDSWTSATRLLIVGGGLIGCE---------VATTARKLGL 167 Query: 222 RSKANIIFNTSLGAIFGVKKYADALQEIIQERNLTVNYKKNLIEVRADKQEAVFENLDKP 281 + L + G ++ L+ ++ E + V ++ + + + + Sbjct: 168 SVTILEAGDELLVRVLG-RRIGAWLRGLLTELGVQVELGTGVVGF--SGEGQLEQVMASD 224 Query: 282 GETQVISYEMLHVTPPMSPPDVLKTSPVADAAGWVDVDKETLQHRRYPNVFGIGDCTNLP 341 G + V ++ + + + +A G V + VF +GD + P Sbjct: 225 GRSFVADSALI-CVGAEPADQLARQAGLACDRG---VIVDHCGATLAKGVFAVGDVASWP 280 Query: 342 T 342 Sbjct: 281 L 281 >3ICS-A nrPDB Length = 588 Score = 45.1 bits (105), Expect = 6e-05, Method: Composition-based stats. Identities = 59/357 (16%), Positives = 124/357 (34%), Gaps = 42/357 (11%) Query: 23 GTQQVGPLQLHTGASHAARNHYEVLVLGGGSGGITMAARMKRKVGAENVAIVEPSERHFY 82 G QQ+G L+ +++V+GG +GG ++AAR++R + + +VE E + Sbjct: 17 GGQQMGR-TLYDDDDKDRWGSRKIVVVGGVAGGASVAARLRRLSEEDEIIMVERGEYISF 75 Query: 83 --QPIWTLVGAGAKQLSSSGRPTASVIPSGVEW---IKARVTELNPDKN-----CIHTDD 132 + +G + T + + + V ++N ++ + T++ Sbjct: 76 ANCGLPYYIGGVITERQKLLVQTVERMSKRFNLDIRVLSEVVKINKEEKTITIKNVTTNE 135 Query: 133 DEKISYRYLIIALGIQLDYEKIKGLPEGFAHPKIGSNYSVKTVEKTWKALQDFKEGNAIF 192 +Y LI++ G + I G+ E A ++++ V T + E Sbjct: 136 TYNEAYDVLILSPGAKPIVPSIPGIEEAKAL------FTLRNVPDTDRIKAYIDEKKP-- 187 Query: 193 TFPNTPVKCAGAPQKIMYLSEAYFRKTGKRSKANIIFNTSLGAIFGVKKYADALQEIIQE 252 G + + E R+ G + N + I + A + E ++ Sbjct: 188 ----RHATVIGGGFIGVEMVEN-LRERGIEVTLVEMANQVMPPI--DYEMAAYVHEHMKN 240 Query: 253 RNLTVNYKKNLIEVRADKQEAVFENLDKPGETQVISYEMLHV-TPPMSPPDVLKTSPVAD 311 ++ + ++ + + + AV VI +ML + + K + +A Sbjct: 241 HDVELVFEDGVDALEEN--GAVVRLKSGS----VIQTDMLILAIGVQPESSLAKGAGLAL 294 Query: 312 AAGWVDVDKETLQHRRYPNVFGIGDCTNL--------PTSKTAAAVAAQSGILDRTI 360 E Q P+++ IGD + A Q +L I Sbjct: 295 GVRGTIKVNEKFQTSD-PHIYAIGDAIEVKDFVTETETMIPLAWPANRQGRMLADII 350 >4NTC-A nrPDB Length = 335 Score = 42.8 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 38/335 (11%), Positives = 100/335 (29%), Gaps = 36/335 (10%) Query: 44 YEVLVLGGGSGGITMAARMKRKVGAENVAIVEPSERHFYQPIWTLVGAGAKQLSSSGRPT 103 +VL++G G G++ A + R++ V Q + ++G + + Sbjct: 15 VDVLIIGAGPAGLSTATGLARQLHTAVVFDSGVYRNAKTQHMHNVLGWDHRNPAELRAAG 74 Query: 104 AS---VIPSGVEWIKARVTELNPDKNCIHTDD--------DEKISYRYLIIALGIQLDYE 152 + S +++ + + + + T+ R +++A G++ Sbjct: 75 RADLTTRYSTIQFQNSTIEAI----RQVETNQLFEARDNEGHSWYGRKVVLATGVRDIPL 130 Query: 153 KIKGLPEGFAHPKIGSNYSVKTVEKTWKALQDFKEGNAIFTFPNTPVKCAGAPQKIMYLS 212 I+G E +A+ + E+ + + G P + Sbjct: 131 DIEGYSECWANGIYHCLFCDGYEERGQETVGVLALGPI-----ANPAR------------ 173 Query: 213 EAYFRKTGKRSKANIIFNTSLGAIFGVKKYADALQEIIQERNLTVNYKKNLIEVRADKQE 272 + + R ++ T+ + A + + L + + Sbjct: 174 ALHLARMALRLSESVTIYTNGNEQLAKEIQQAAEESPVGASGLKFEARP-IRRFEKGDVA 232 Query: 273 AVFENLDKPGETQVISYEMLHVTPPMSPPDVLKTSPVADAAGWVDVDKETLQHRRYPNVF 332 E++ + + + ++ P + + G + + P VF Sbjct: 233 KTVIVHLGESESKTEGFLVYNPQTEVNGPFAKQLALNMTEGGDILTTPPFYETSV-PGVF 291 Query: 333 GIGDCTNLPTSKTAAAVAAQSGILDRTISVIMKNQ 367 +GDC P K + + + ++ Q Sbjct: 292 AVGDC-ATPL-KAVTPAVSMGSLAAGGLVAQLQAQ 324 >1V59-A nrPDB Length = 478 Score = 42.8 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 23/127 (18%), Positives = 49/127 (38%), Gaps = 9/127 (7%) Query: 223 SKANIIFNTSLGAIFGVKKYADALQEIIQERNLTVNYKKNLIEVRADKQEAVFENL--DK 280 SK ++ + A A Q+ ++++ L +I + + + V E + D Sbjct: 207 SKVTVVEFQPQIGASMDGEVAKATQKFLKKQGLDFKLSTKVISAKRNDDKNVVEIVVEDT 266 Query: 281 PGETQV-ISYEMLHVT---PPMSPPDVLKTSPV-ADAAGWVDVDKETLQHRRYPNVFGIG 335 Q + E+L V P + + D G + +D + + ++P++ +G Sbjct: 267 KTNKQENLEAEVLLVAVGRRPYIAGLGAEKIGLEVDKRGRLVIDDQF--NSKFPHIKVVG 324 Query: 336 DCTNLPT 342 D T P Sbjct: 325 DVTFGPM 331 >2YQU-A nrPDB Length = 455 Score = 42.4 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 25/119 (21%), Positives = 50/119 (42%), Gaps = 9/119 (7%) Query: 241 KYADALQEIIQERNLTVNYKKNLIEVRADKQEAVFENLDKPGETQVISYEMLHV-TPPMS 299 + + A + + +++ LT+ + V + + A E + GE ++ V P + Sbjct: 209 EVSRAAERVFKKQGLTIRTGVRVTAVVPEAKGARVEL--EGGEVLEADRVLVAVGRRPYT 266 Query: 300 PPDVLKTSPV-ADAAGWVDVDKETLQHRRYPNVFGIGDCTNLPTSKTAAAVAAQSGILD 357 L+ + + D G + VD+ R P+++ IGD P A A++ GI Sbjct: 267 EGLSLENAGLSTDERGRIPVDEHL--RTRVPHIYAIGDVVRGPM---LAHKASEEGIAA 320 >5J5Z-A nrPDB Length = 496 Score = 40.9 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 24/123 (19%), Positives = 48/123 (39%), Gaps = 10/123 (8%) Query: 227 IIFNTSLGAIFGVKKYADALQEIIQERNLTVNYKKNLI---EVRADKQEAVFENLDKPGE 283 + F +G + + + Q I+Q++ + + K + E G+ Sbjct: 229 VEFLGHVGGVGIDMEISKNFQRILQKQGFKFKLNTKVTGATKKSDGKIDVSIEAASG-GK 287 Query: 284 TQVISYEMLHVT---PPMSPPDVLKTSPV-ADAAGWVDVDKETLQHRRYPNVFGIGDCTN 339 +VI+ ++L V P + L+ + D G + V+ Q + PN++ IGD Sbjct: 288 AEVITCDVLLVCIGRRPFTKNLGLEELGIELDPRGRIPVNTR-FQT-KIPNIYAIGDVVA 345 Query: 340 LPT 342 P Sbjct: 346 GPM 348 >4FX9-A nrPDB Length = 453 Score = 40.1 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 30/143 (20%), Positives = 57/143 (39%), Gaps = 5/143 (3%) Query: 43 HYEVLVLGGGSGGITMAARMKRKVGAENVAIVEPSERHFYQPI-WTLVGAGAKQLSSSGR 101 +V+++GGG+ G++ A+R+KR +V + E +E + P V G Sbjct: 6 KKKVVIIGGGAAGMSAASRVKRLKPEWDVKVFEATEWVSHAPCGIPYVVEGLSTPDKLMY 65 Query: 102 --PTASVIPSGVEW-IKARVTELNPDKNCIHTDDDEK-ISYRYLIIALGIQLDYEKIKGL 157 P + G++ + A V E++ + + EK + YL+ A G I+G+ Sbjct: 66 YPPEVFIKKRGIDLHLNAEVIEVDTGYVRVRENGGEKSYEWDYLVFANGASPQVPAIEGV 125 Query: 158 PEGFAHPKIGSNYSVKTVEKTWK 180 ++ E K Sbjct: 126 NLKGVFTADLPPDALAIREYMEK 148 >1FOB-A nrPDB Length = 334 Score = 39.4 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 33/197 (16%), Positives = 57/197 (28%), Gaps = 33/197 (16%) Query: 103 TASVIPSGVEWIKARVTELNPDKNCIHTDDDEKIS---YRY-LIIALG----IQLDYEKI 154 +++ SG +K P K IH DD Y Y ++A G DY + Sbjct: 154 IGALLHSGAWGVKDSNLATTP-KIMIHLDDGWSWDQQNYFYETVLATGELLSTDFDYFGV 212 Query: 155 KGLPEGFAHPKIGSNYSVKTVEKTWKALQDFKEGNAIFTFPNTPVKCAGAPQKIMYLSEA 214 P A + S+KT + LQ + + N PV C Sbjct: 213 SYYPFYSASATLA---SLKT---SLANLQSTYDKPVVVVETNWPVSCPNPAYAFPSDL-- 264 Query: 215 YFRKTGKRSKANIIFNTSLGAIFGVKKYADALQEII--------QERNLTVNYKKNLIEV 266 S + + +A + + N + + Sbjct: 265 --------SSIPFSVAGQQEFLEKLAAVVEATTDGLGVYYWEPAWIGNAGLGSSCADNLM 316 Query: 267 RADKQEAVFENLDKPGE 283 + V+E+++ GE Sbjct: 317 VDYTTDEVYESIETLGE 333 >5JCN-A nrPDB Length = 451 Score = 39.0 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 45/284 (15%), Positives = 80/284 (28%), Gaps = 29/284 (10%) Query: 106 VIPSGVEWI-KARVTELNPDKNCIHTDDDEKISYRYLIIALG---IQLDYEKIKGLPEGF 161 G+E I + + + + + +Y LIIA G I+L +G Sbjct: 99 YSEKGIELILSTEIVKADLASKTLTSAVGATFTYEILIIATGSSVIKLSDFGTQGADSNN 158 Query: 162 AHPKIGSNYSVKTVEKTWKALQDFKEGNAIFTFPNTPVKCAGAPQKIMYLSEAYFRKTGK 221 + + +K A+Q K G A+ G I A + Sbjct: 159 ILYLREVDDA----DKLVAAIQAKKGGKAVIV---------GGGY-IGLELSAALKINDF 204 Query: 222 RSKANIIFNTSLGAIFGVKKYADALQEIIQERNLTVNYKKNLIEVRADKQEAVFENLDKP 281 + +F A + + + + + AD V K Sbjct: 205 DVTMVFPEPWCMPRLFT-ADIAAFYESYYTNKGVKIVKGTVAVGFDADANGDVTAVNLKN 263 Query: 282 GETQVISYEMLHVTPPMSPPDVLKTSPVADAAGWVDVDKETLQHRRYPNVFGIGDCTNLP 341 G +++ V P L VA+ G + D P V+ +GD P Sbjct: 264 GSVLE--ADIVVVGVGGRPLTTLFKGQVAEEKGGIKTD--AFFETSVPGVYAVGDVATFP 319 Query: 342 TS-----KTAAAVAAQSGILDRTISVIMKNQTPTKKYDGYTSCP 380 + V ++ + I K + + Y P Sbjct: 320 MKMYNELRRVEHVDHARKSAEQAVKAI-KGKESGESVVEYDYLP 362 >1ZK7-A nrPDB Length = 467 Score = 38.6 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 33/234 (14%), Positives = 68/234 (29%), Gaps = 32/234 (13%) Query: 111 VEWIKARVTELNPDKNCIHTDDDEK--ISYRYLIIALGIQLDYEKIKGLPEGFAHPKIGS 168 + + + + ++ + + + ++A G I GL E S Sbjct: 110 ITVVHGEARFKDDQSLTVRLNEGGERVVMFDRCLVATGASPAVPPIPGLKE--------S 161 Query: 169 NYSVKTVEKTWKALQDFKEGNAIFTFPNTPVKCAGAPQKIMYLSEAYFRKTGKRSKANII 228 Y W + + + F + G SK ++ Sbjct: 162 PY--------WTSTEALASDTIPERLAVIGSSV------VALELAQAFARLG--SKVTVL 205 Query: 229 FNTSLGAIFGVKKYADALQEIIQERNLTVNYKKNLIEVRADKQEAVFENLDKPGETQVIS 288 +L +A+ + + V +V + F GE + Sbjct: 206 ARNTLFFREDPA-IGEAVTAAFRAEGIEVLEHTQASQVA--HMDGEFVLTTTHGELRADK 262 Query: 289 YEMLHVTPPMSPPDVLKTSPVA-DAAGWVDVDKETLQHRRYPNVFGIGDCTNLP 341 + P + L + V +A G + +D+ PN++ GDCT+ P Sbjct: 263 LLVATGRTPNTRSLALDAAGVTVNAQGAIVIDQGMRTSN--PNIYAAGDCTDQP 314 >2WOV-A nrPDB Length = 495 Score = 38.2 bits (87), Expect = 0.008, Method: Composition-based stats. Identities = 44/314 (14%), Positives = 101/314 (32%), Gaps = 47/314 (14%) Query: 29 PLQLHTGASHAARNHYEVLVLGGGSGGITMAARMKRKVGAENVAIVEPSERHFYQPIWTL 88 P +L + + E G G ++ A K+ + A+N A+++ ++ + Sbjct: 62 PKKLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSY-------E 114 Query: 89 VGAGAKQLSSSGRPTASVIPSGVEWIKARVTELNPDKNCIHTDDDEKISYRYLIIALGIQ 148 + S+ V ++ +P E++ ++++A G Sbjct: 115 GMFNDTEGLDFFLGWGSLESKNVVVVRETA---DPKS-----AVKERLQADHILLATGSW 166 Query: 149 LDYEKIKGLPEGFAHPKIGSNYSVKTVEKTWKALQDFKEGNAIFTFPNTPVKCAGAPQKI 208 I G+ + SN + E + L G + + Sbjct: 167 PQMPAIPGIEHCIS-----SNEAFYLPEPPRRVL---TVGGGFISV------------EF 206 Query: 209 MYLSEAYFRKTGKRSKANIIFNTSLGAIFGVKKYADALQEIIQERNLTVNYKKNLIEVRA 268 + AY K + + +L + + + + + + + +N +V Sbjct: 207 AGIFNAY---KPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGIEIMTNENPAKVSL 263 Query: 269 DKQEAVFENLDKPGETQVISYEMLHVTP---PMSPPDVLKTSPV-ADAAGWVDVDKETLQ 324 + + + G+T + +++ + P + L V G V VD+ Sbjct: 264 NTDGSKHVTF-ESGKTLDV--DVVMMAIGRIPRTNDLQLGNVGVKLTPKGGVQVDE--FS 318 Query: 325 HRRYPNVFGIGDCT 338 PN++ IGD T Sbjct: 319 RTNVPNIYAIGDIT 332 >5YGQ-A nrPDB Length = 342 Score = 37.4 bits (85), Expect = 0.011, Method: Composition-based stats. Identities = 45/309 (14%), Positives = 88/309 (28%), Gaps = 36/309 (11%) Query: 46 VLVLGGGSGGITMAARM-KRKVGAENVAIVE----------PSERHFYQPIWTLVGAG-- 92 VL++G G G+ + V A V I++ P + + P +V Sbjct: 9 VLIVGAGPCGLFAVFELGLLDVKAHLVDILDKVGGQCAELYPEKPIYDIPGIPMVTGHGL 68 Query: 93 AKQLSSSGRPTASVIPSGVEWIKARVTELNPDKNCIHTDDDEKISYRYLIIALGIQLDYE 152 + L +P + + V ++ + T+ + L++A G Sbjct: 69 TEALMEQIKPFNPTFH--LSEMVENVEKIGDPGFRVTTNAGKVFECTVLVVAAGGGSFLP 126 Query: 153 KIKGLPEGFAHPKIGSNYSVKTVEKTWKALQDFKEGNAIFTFPNTPVKCAGAPQKIMYLS 212 K +P A+ +Y+V + ++DF+ + + Sbjct: 127 KRPPVPGVEAYEGTSVHYAV-------RKMEDFRGKDILIVGGG----------DSALDW 169 Query: 213 EAYFRKTGKRSKANIIFNTSLGAIFGVKKYADALQEIIQERNLTVNYKKNLIEVRADKQE 272 K + GA V++ + + +L + L Sbjct: 170 TLNLNPIAKSMTLVHRRDDFRGAPHSVEQMRQLVASG--KLDLKIGQITELQGDNGQLTG 227 Query: 273 AVFENLDKPGETQVISYEMLHVTPPMSPPDVLKTSPVADAAGWVDVDKETLQHRRYPNVF 332 A + D + M V + + VD T + P +F Sbjct: 228 ATVKLNDNTTSQIKCDAMLPFFGLTMKLGPVA-NWGLDLENNLIPVDTGTFET-NVPGIF 285 Query: 333 GIGDCTNLP 341 IGD P Sbjct: 286 AIGDINTYP 294 >4ZN0-A nrPDB Length = 311 Score = 37.0 bits (84), Expect = 0.018, Method: Composition-based stats. Identities = 48/339 (14%), Positives = 109/339 (32%), Gaps = 39/339 (11%) Query: 36 ASHAARNHYEVLVLGGGSGGITM-AARMKRKVGA-----ENVA-IVEPSERHFYQPIWTL 88 SH A + Y+++++GGG G+T ++ + ++ + ++ P + Sbjct: 1 GSHMA-SMYDLIIIGGGPAGLTAGIYAVRYGLDTLILERNEISGQISMADIVENYPGFPS 59 Query: 89 VGAGAKQLSSSGRPTASVIPSGVEWIKARVTELNPDK-NCIHTDDDEKISYRYLIIALGI 147 + L R GV+ V + + I T D + + +IIA G Sbjct: 60 ISG----LELMERFRTHAQEVGVKTTITEVLSVRSEGTKKIITTDSGDLEAKAVIIATGA 115 Query: 148 QLDYEKIKGLPEGFAHPKIGSNYSVKTVEKTWKALQDFKEGNAIFTFPNTPVKCAGAPQK 207 + + G E + S ++ F + A Sbjct: 116 NPKHLGVPGEKELISKGV--SYCAICDG--------PFFRNKIVAVVGGGNSAVTDALFL 165 Query: 208 IMYLSEAYFRKTGKRSKANIIFNTSLGAIFGVKKYADALQEIIQERNLTVNYKKNLIEVR 267 + Y KA + + ++ ++ V ++ + +V Sbjct: 166 SKVAQKVYLVHRRDHLKAARVLQDRVDGTPNIELILNS------HVLEIVGTREGIKKV- 218 Query: 268 ADKQEAVFENLDKPGETQVISYEMLHVTPPMSPP-DVLKTSPVADAAGWVDVDKETLQHR 326 ++ + E+++ ET+ +S + + + P + + D G++ D+ Sbjct: 219 ---EKIILEDVNSR-ETRELSTNGVFIYVGIHPNTEFVDVEK--DEGGFIKTDRWMETSE 272 Query: 327 RYPNVFGIGDCTNLPTSKTAAAVAAQSGILDRTISVIMK 365 ++ GDC + P + AV + I K Sbjct: 273 --KGIYAAGDCRDTPIWQLVTAVRDGAIAATAAYEYIEK 309 >2A87-A nrPDB Length = 335 Score = 36.7 bits (83), Expect = 0.020, Method: Composition-based stats. Identities = 53/332 (15%), Positives = 98/332 (29%), Gaps = 46/332 (13%) Query: 32 LHTGASHAARNHYEVLVLGGGSGGITMAARMKRKVGAENV--------AIVEPSERHFYQ 83 +H A H R+ V+V+G G G T A R A V A++ ++ Y Sbjct: 6 VHDRAHHPVRD---VIVIGSGPAGYTAALYAARAQLAPLVFEGTSFGGALMTTTDVENY- 61 Query: 84 PIWTLVGAGAKQLSSSGRPTASVIPSGVEWIKARVTELNPDK--NCIHTDDDEKISYRYL 141 P + G + + + G + V ++ + T D + R + Sbjct: 62 PGFRNGITGPELMDEMR---EQALRFGADLRMEDVESVSLHGPLKSVVTADGQTHRARAV 118 Query: 142 IIALGIQLDYEKIKGLPEGFAHPKIGSNYSVKTVEKTWKALQDFKEGNAIFTFPNTPVKC 201 I+A+G Y ++ G E S+ + F++ + Sbjct: 119 ILAMGAAARYLQVPGEQELLGRGV--SSCATCDG-------FFFRDQDIAVIGGGD---- 165 Query: 202 AGAPQKIMYLSEAYFRKTGKRSKANIIFNTSLGAIFGVKKYADALQEIIQERNLTVNYKK 261 + EA F RS T + + L + Sbjct: 166 -------SAMEEATFLTRFARS------VTLVHRRDEFRASKIMLDRARNNDKIRFLTNH 212 Query: 262 NLIEVRADK--QEAVFENLDKPGETQVISYEMLHVTPPMSPPDVLKTSPVADAAGWVDVD 319 ++ V D + + ET + + +++ + D G+V V Sbjct: 213 TVVAVDGDTTVTGLRVRDTNTGAETTLPVTGVFVAIGHEPRSGLVREAIDVDPDGYVLVQ 272 Query: 320 KETLQHRRYPNVFGIGDCTNLPTSKTAAAVAA 351 T P VF GD + + A + Sbjct: 273 GRTTSTSL-PGVFAAGDLVDRTYRQAVTAAGS 303 >5VDN-A nrPDB Length = 463 Score = 36.3 bits (82), Expect = 0.031, Method: Composition-based stats. Identities = 54/294 (18%), Positives = 104/294 (35%), Gaps = 39/294 (13%) Query: 124 DKNCIHTDDDEKISYRYLIIALGIQLDYEKIKGLPEGFAHPKIGSNYSVKTVEKTWKALQ 183 D + + + E I+ +++IA G + + I G G + L Sbjct: 132 DAHTVEVN-GETITADHILIATGGRPSHPDIPGAEYGIDS-------------DGFFELD 177 Query: 184 DFKEGNAIFTFPNTPVKCAGAPQKIMYLSEAYFRKTGK-RSKANIIFNTSLGAIFGVKKY 242 + + A+ V+ AG + + + RK R+ +I T L Sbjct: 178 EMPKRVAVVGAGYIAVEIAGVLNGLGTETHLFVRKHAPLRTFDPLIVETLL--------- 228 Query: 243 ADALQEIIQERNLTVNYKKNLIEVRADKQEAVFENLDKPGETQVISYEMLHVTPPMSPPD 302 E++ ++ + V + ++ L+ E V P + Sbjct: 229 -----EVMNTEGPKLHTESVPKAVIKNADGSLTLQLENGTEVTVDHLIWAIGREPATDNL 283 Query: 303 VLKTSPV-ADAAGWVDVDKETLQHRRYPNVFGIGDCTNLPTSKTAAAVAAQSGILDRTIS 361 L + V + G+++VDK Q+ ++ +GD T + T AVAA + +R Sbjct: 284 NLSVTGVKTNDKGYIEVDK--FQNTNVKGIYAVGDNTGV-VELTPVAVAAGRRLSER--- 337 Query: 362 VIMKNQTPTKKYDGYTSCPLVTGYNRVILAEFDYKAEPLETFPFDQSKERLSMY 415 + N P ++ Y++ P V + I + + E F DQ K S + Sbjct: 338 --LFNNKP-DEHLDYSNIPTVVFSHPPIGTIGLTEPQAREKFGDDQVKVYTSSF 388 >4JDR-A nrPDB Length = 474 Score = 35.5 bits (80), Expect = 0.044, Method: Composition-based stats. Identities = 26/119 (21%), Positives = 44/119 (36%), Gaps = 6/119 (5%) Query: 245 ALQEIIQERNLTVNYKKNLIEVRADKQEAVFENLDKPGETQVISYEMLHV--TPPMSPPD 302 + I ++ NL + K +E + D E P E Q ++ + P D Sbjct: 222 FTKRISKKFNLMLETKVTAVEAKEDGIYVTMEGKKAPAEPQRYDAVLVAIGRVPNGKNLD 281 Query: 303 VLKTSPVADAAGWVDVDKETLQHRRYPNVFGIGDCTNLPTSKTAAAVAAQSGILDRTIS 361 K D G++ VDK+ + P++F IGD P A + + I+ Sbjct: 282 AGKAGVEVDDRGFIRVDKQLRTNV--PHIFAIGDIVGQPM--LAHKGVHEGHVAAEVIA 336 >6B4O-A nrPDB Length = 452 Score = 35.5 bits (80), Expect = 0.050, Method: Composition-based stats. Identities = 47/270 (17%), Positives = 84/270 (31%), Gaps = 44/270 (16%) Query: 170 YSVKTVEKT-WKALQDFKEGNAIFTFPNTPVKCAGAPQKIMYLSEAYFRKTGKRSKANII 228 Y+ T E+T ++ + + P K ++ S +F + + Sbjct: 116 YATFTGEQTIEVNGTEYTAPHILIATGGRPKKLGIPGEEYALDSNGFFALEEMPKRVVFV 175 Query: 229 FNTSLGAIFGVKKYADALQEIIQERNLTVNYKKNLIEVRADKQEAVFENLDKPGETQVIS 288 GA + + A L + E + +++ L E V E + G + Sbjct: 176 -----GAGYIAAELAGTLHGLGAETHWAFRHERPLRSFDDMLSEKVVERYQEMGMQIHPN 230 Query: 289 Y-------------------------EMLHVTPPMSPPD---VLKTSPVA-DAAGWVDVD 319 + + P L+ + VA D G+V VD Sbjct: 231 ATPAKIEKTAQNEYVITFENGESITTDAVIFGTGRQPNTDQLGLENTKVALDEKGYVKVD 290 Query: 320 KETLQHRRYPNVFGIGDCTNLPTSKTAAAVAAQSGILDRTISVIMKNQTPTKKYDGYTSC 379 K Q+ ++ +GD T A+AA + +R + Q T Y Y Sbjct: 291 K--FQNTTQNGIYAVGDV-IGKIDLTPVAIAAGRRLSER----LFNGQ--TDLYLDYNLV 341 Query: 380 PLVTGYNRVILAEFDYKAEPLETFPFDQSK 409 P V + + + LE + DQ K Sbjct: 342 PTVVFTHPPVATIGLTEKAALEEYGEDQVK 371 >5U25-A nrPDB Length = 602 Score = 35.5 bits (80), Expect = 0.050, Method: Composition-based stats. Identities = 25/118 (21%), Positives = 44/118 (37%), Gaps = 12/118 (10%) Query: 245 ALQEIIQERNLTVNYKKNLIEVRADKQEAVFENLDKPGETQVISYEMLHVTPPMSPPD-- 302 Q + N+ VN K +E + D FE + P E Q + P+ Sbjct: 352 QKQNEYRFDNIMVNTKTVAVEPKEDGVYVTFEGANAPKEPQRYDA---VLVAAGRAPNGK 408 Query: 303 --VLKTSPVA-DAAGWVDVDKETLQHRRYPNVFGIGDCTNLPTSKTAAAVAAQSGILD 357 + + VA G+++VDK+ + P+++ IGD P A + + Sbjct: 409 LISAEKAGVAVTDRGFIEVDKQMRTNV--PHIYAIGDIVGQPM--LAHKAVHEGHVAA 462 >1F8S-A nrPDB Length = 498 Score = 35.5 bits (80), Expect = 0.051, Method: Composition-based stats. Identities = 13/50 (26%), Positives = 23/50 (46%), Gaps = 2/50 (4%) Query: 30 LQLHTGASHAARNHYEVLVLGGGSGGITMAARMKRKVGAENVAIVEPSER 79 L++ A N V+++G G G++ A + V ++E SER Sbjct: 20 LEIARNGLKATSNPKHVVIVGAGMAGLSAAYVLAGA--GHQVTVLEASER 67 >5W1J-A nrPDB Length = 584 Score = 35.1 bits (79), Expect = 0.056, Method: Composition-based stats. Identities = 42/269 (15%), Positives = 80/269 (29%), Gaps = 42/269 (15%) Query: 104 ASVIPSGVEWIKARVTELNPDKNCIHTDDD--EKISYRYLIIALGIQLDYEKIKGLPEGF 161 +S++ + V+++ A ++P + I+ +I+A G + Y I G E Sbjct: 208 SSMMNANVKYLNALGEIVDPHTIKTTNKQGIVKNITTNTIIVATGERPRYPPIPGAKEYG 267 Query: 162 AHPKIGSNYSVKTVEKTWKALQDFKEGNAIFTFPNTPVKCAGAPQKIMYLSEAYFRKTGK 221 T L C GA + + G Sbjct: 268 I---------------TSDDLFTLDHNPGKTL-------CVGASY-VSLECAGFLSSIGC 304 Query: 222 RSKANIIFNTSLGAIFGVKKYADALQEIIQERNLTVNYKKN------LIEVRADKQEAVF 275 + S+ ++ A + + I + + L E + + Sbjct: 305 DVTVMV---RSIFLRGFDQQMAGLISDYIAKYGVKFVRPCVPTSVRCLEEYDPESGKLAI 361 Query: 276 ENLDKPGETQVISYEMLHVT------PPMSPPDVLKTSPVADAAGWVDVDKETLQHRRYP 329 ++ E + + P + L+ V G V VD E + P Sbjct: 362 YEVEGKHEDGTPFKDTFNTVLFAVGRDPCTTNIGLQNVDVKTTNGRVVVDDE--ERTNVP 419 Query: 330 NVFGIGDCTNLPTSKTAAAVAAQSGILDR 358 N++ IGD +N T A+ A + R Sbjct: 420 NIYAIGDVSNAGYQLTPLAIQAGKNLARR 448 >1REO-A nrPDB Length = 486 Score = 35.1 bits (79), Expect = 0.057, Method: Composition-based stats. Identities = 14/50 (28%), Positives = 23/50 (46%), Gaps = 2/50 (4%) Query: 30 LQLHTGASHAARNHYEVLVLGGGSGGITMAARMKRKVGAENVAIVEPSER 79 L++ A N V+V+G G G++ A + V ++E SER Sbjct: 20 LEIARNGLKATSNPKHVVVVGAGMSGLSAAYVLSGA--GHQVTVLEASER 67 >1OJT-A nrPDB Length = 482 Score = 35.1 bits (79), Expect = 0.057, Method: Composition-based stats. Identities = 25/118 (21%), Positives = 44/118 (37%), Gaps = 12/118 (10%) Query: 245 ALQEIIQERNLTVNYKKNLIEVRADKQEAVFENLDKPGETQVISYEMLHVTPPMSPPD-- 302 Q + N+ VN K +E + D FE + P E Q + P+ Sbjct: 233 QKQNEYRFDNIMVNTKTVAVEPKEDGVYVTFEGANAPKEPQRYDA---VLVAAGRAPNGK 289 Query: 303 --VLKTSPVA-DAAGWVDVDKETLQHRRYPNVFGIGDCTNLPTSKTAAAVAAQSGILD 357 + + VA G+++VDK+ + P+++ IGD P A + + Sbjct: 290 LISAEKAGVAVTDRGFIEVDKQMRTNV--PHIYAIGDIVGQPM--LAHKAVHEGHVAA 343 >3Q6J-A nrPDB Length = 523 Score = 35.1 bits (79), Expect = 0.062, Method: Composition-based stats. Identities = 44/322 (13%), Positives = 95/322 (29%), Gaps = 44/322 (13%) Query: 81 FYQPIWTLVGAGAKQLSSSGRPTASVIPSGV-EWIKARVTELN---------PDKNCIHT 130 ++ P T G K++ R + P G+ + L D + + Sbjct: 110 YWFPDMTEKVVGIKEVVDLFRAGRNG-PHGIMNFQSKEQLNLEYILNCPAKVIDNHTVEA 168 Query: 131 DDDEKISYRYLIIALGIQLDYEKIKGLPEGFAHPKIGSNYSVKTVEKTWKALQDFKEGNA 190 + + LI+A+G + G+ K +++ E D++ G+ Sbjct: 169 A-GKVFKAKNLILAVGAGPGTLDVPGVN-----AKGVFDHATLVEE------LDYEPGST 216 Query: 191 IFTFPNTPVKCAGAPQKIMYLSEAYFRKTGKRSKANIIFNTSLGAIFGVKKYADALQEII 250 + + F TG+R+ ++ T + + + + + Sbjct: 217 VVVVGGSKTAVEYGCF---------FNATGRRT--VMLVRTEPLKLIKDNETRAYVLDRM 265 Query: 251 QERNLTVNYKKNLIEVRADKQEAVFENL--DKPGET-QVISYEMLHVTPPMSPPDVLKTS 307 +E+ + + N+ + D V + GE + L + ++ K Sbjct: 266 KEQGMEIISGSNVTRIEEDANGRVQAVVAMTPNGEMRIETDFVFLGLGEQPRSAELAKIL 325 Query: 308 PV-ADAAGWVDVDKETLQHRRYPNVFGIGDCTNLPTSKTAAAVAAQSGILDRTISVIMKN 366 + G V V++ PNV+ +GD P R + + Sbjct: 326 GLDLGPKGEVLVNEYLQTSV--PNVYAVGDLIGGPM--EMFKARKSGCYAARNVMGEKIS 381 Query: 367 QTPT--KKYDGYTSCPLVTGYN 386 TP + G Sbjct: 382 YTPKNYPDFLHTHYEVSFLGMG 403 >4YKF-A nrPDB Length = 521 Score = 34.4 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 49/345 (14%), Positives = 105/345 (30%), Gaps = 68/345 (19%) Query: 38 HAARNHYEVLVLGGGSGGITMAARMKRKVGAENVAIVEPSERHFYQPIWTLVGAGAKQLS 97 ++AR ++G GG ++ V EN V +E G K Sbjct: 230 YSARKGIRTGLMGERFGG-----QILDTVDIENYISVPKTE-------------GQKLAG 271 Query: 98 SSGRPTASVIPSGVEWI-KARVTELNPDK-----NCIHTDDDEKISYRYLIIALGIQLDY 151 + V+ I ++L P + I T + R +I+A G + Sbjct: 272 ALKVHVDEY---DVDVIDSQSASKLIPAAVEGGLHQIETASGAVLKARSIIVATGAKWRN 328 Query: 152 EKIKGLPEGFAHPKIGSNYSVKTVEKTWKALQDFKEGNAIFTFPNTPVKCAGAPQKIMYL 211 + G + + + K + A+ N+ V+ A + + Sbjct: 329 MNVPGEDQYRTKGVTYCPHCDGPLFKGKRV--------AVIGGGNSGVE---AAIDLAGI 377 Query: 212 SEAYFRKTGKRSKANIIFNTSLGAIFGVKKYADALQEIIQERNLTVNYKKNLIEVRADKQ 271 E + + + D L+ + +N+ + EV+ D Sbjct: 378 VEH------------VTLLEFAPEMKADQVLQDKLRSL---KNVDIILNAQTTEVKGDGS 422 Query: 272 EAV----FENLDKPGETQVISYEMLH--VTPPMS--PPDVLKTSPVADAAGWVDVDKETL 323 + V + + ++ + + P + V + + G + +D + Sbjct: 423 KVVGLEYRDRVSGDIHNIELAGIFVQIGLLPNTNWLEGAVER-----NRMGEIIIDAKCE 477 Query: 324 QHRRYPNVFGIGDCTNLPTSKTAAAVAAQSGILDRTISVIMKNQT 368 + VF GDCT +P + A + +++ +T Sbjct: 478 TNV--KGVFAAGDCTTVPYKQIIIATGEGAKASLSAFDYLIRTKT 520 >1FL2-A nrPDB Length = 310 Score = 34.4 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 49/345 (14%), Positives = 105/345 (30%), Gaps = 68/345 (19%) Query: 38 HAARNHYEVLVLGGGSGGITMAARMKRKVGAENVAIVEPSERHFYQPIWTLVGAGAKQLS 97 ++AR ++G GG ++ V EN V +E G K Sbjct: 19 YSARKGIRTGLMGERFGG-----QILDTVDIENYISVPKTE-------------GQKLAG 60 Query: 98 SSGRPTASVIPSGVEWI-KARVTELNPDK-----NCIHTDDDEKISYRYLIIALGIQLDY 151 + V+ I ++L P + I T + R +I+A G + Sbjct: 61 ALKVHVDEY---DVDVIDSQSASKLIPAAVEGGLHQIETASGAVLKARSIIVATGAKWRN 117 Query: 152 EKIKGLPEGFAHPKIGSNYSVKTVEKTWKALQDFKEGNAIFTFPNTPVKCAGAPQKIMYL 211 + G + + + K + A+ N+ V+ A + + Sbjct: 118 MNVPGEDQYRTKGVTYCPHCDGPLFKGKRV--------AVIGGGNSGVE---AAIDLAGI 166 Query: 212 SEAYFRKTGKRSKANIIFNTSLGAIFGVKKYADALQEIIQERNLTVNYKKNLIEVRADKQ 271 E + + + D L+ + +N+ + EV+ D Sbjct: 167 VEH------------VTLLEFAPEMKADQVLQDKLRSL---KNVDIILNAQTTEVKGDGS 211 Query: 272 EAV----FENLDKPGETQVISYEMLH--VTPPMS--PPDVLKTSPVADAAGWVDVDKETL 323 + V + + ++ + + P + V + + G + +D + Sbjct: 212 KVVGLEYRDRVSGDIHNIELAGIFVQIGLLPNTNWLEGAVER-----NRMGEIIIDAKCE 266 Query: 324 QHRRYPNVFGIGDCTNLPTSKTAAAVAAQSGILDRTISVIMKNQT 368 + VF GDCT +P + A + +++ +T Sbjct: 267 TNV--KGVFAAGDCTTVPYKQIIIATGEGAKASLSAFDYLIRTKT 309 >5KVH-A nrPDB Length = 543 Score = 34.0 bits (76), Expect = 0.14, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 28/72 (38%), Gaps = 10/72 (13%) Query: 76 PSERHFYQPIWTLVGAGAKQLSSSGRPTASVIPSGVEWIKAR-VTELNPDKNCIHTDDDE 134 ++QP V A + + GV + + V +L+ N + +D Sbjct: 123 KERSIYFQPPSFYVSA---------QDLPHIENGGVAVLTGKKVVQLDVRDNMVKLNDGS 173 Query: 135 KISYRYLIIALG 146 +I+Y +IA G Sbjct: 174 QITYEKCLIATG 185 >1GEU-A nrPDB Length = 450 Score = 32.8 bits (73), Expect = 0.28, Method: Composition-based stats. Identities = 54/318 (16%), Positives = 106/318 (33%), Gaps = 44/318 (13%) Query: 96 LSSSGRPTASVIPSG-VEWIKARVTELNPDKNCIHTDDDEKISYRYLIIALGIQLDYEKI 154 + +V+ V+ IK ++ + + E I+ +++IA G + + I Sbjct: 92 IDRIHTSYENVLGKNNVDVIKGFARFVDAKTLEV---NGETITADHILIATGGRPSHPDI 148 Query: 155 KGLPEGFAHPKIGSNYSVKTVEKTWKALQDFKEGNAIFTFPNTPVKCA--GAPQKIMYLS 212 G+ G + + F P P + A GA I Sbjct: 149 PGVEYGI-------------------------DSDGFFALPALPERVAVVGAGY-IGVEL 182 Query: 213 EAYFRKTGKRSKANIIFNTSLGAIFGVKKYADALQEIIQERNLTVNYKKNLIEVRADKQE 272 G ++ +F+ L + ++ L E++ ++ V + Sbjct: 183 GGVINGLGAKTHLFEMFDAPLPSF--DPMISETLVEVMNAEGPQLHTNAIPKAVVKNTDG 240 Query: 273 A-VFENLDKPGETQVISYEMLHVTPPMSPPDVLKTSPVADAAGWVDVDKETLQHRRYPNV 331 + E D ET + P ++ + G++ VDK Q+ + Sbjct: 241 SLTLELEDGRSETVDCLIWAIGREPANDNINLEAAGVKTNEKGYIVVDK--YQNTNIEGI 298 Query: 332 FGIGDCTNLPTSKTAAAVAAQSGILDRTISVIMKNQTPTKKYDGYTSCPLVTGYNRVILA 391 + +GD T T AVAA + +R + N P ++ Y++ P V + I Sbjct: 299 YAVGDNTGA-VELTPVAVAAGRRLSER-----LFNNKP-DEHLDYSNIPTVVFSHPPIGT 351 Query: 392 EFDYKAEPLETFPFDQSK 409 + + E + DQ K Sbjct: 352 VGLTEPQAREQYGDDQVK 369 >3KVE-A nrPDB Length = 486 Score = 32.8 bits (73), Expect = 0.33, Method: Composition-based stats. Identities = 13/50 (26%), Positives = 22/50 (44%), Gaps = 2/50 (4%) Query: 30 LQLHTGASHAARNHYEVLVLGGGSGGITMAARMKRKVGAENVAIVEPSER 79 L++ N V+V+G G G++ A + V ++E SER Sbjct: 20 LEIARNGLKKTSNPKHVVVVGAGMSGLSAAYVLAGA--GHKVTVLEASER 67 >4JNQ-A nrPDB Length = 345 Score = 32.0 bits (71), Expect = 0.47, Method: Composition-based stats. Identities = 56/367 (15%), Positives = 100/367 (27%), Gaps = 60/367 (16%) Query: 27 VGPLQLHTGA-SHAARNHYEVLVLGGGSGGITMAARMKRKV-------GAENVAIVEPSE 78 +G L+ T + H V+V+G G G T A R + G + + + Sbjct: 9 MGTLEAQTQGPGSMTQRHAPVIVIGSGPAGYTAAIYAARAMLKPVVIAGLQQGGQLMITT 68 Query: 79 RHFYQPIWTLVGAGAKQLSSSGRPTASVIPSGVEWIKARVTELNPDKN--CIHTDDDEKI 136 P + G + R +V G + + +TE+ + D Sbjct: 69 DVENYPGYAEPVQGPWMMEQMARQAENV---GAQIVHDIITEVETTVRPFRLKGDSGTIY 125 Query: 137 SYRYLIIALGIQLDYEKIKGLPEGFAHPKIGSNYSVKTVEKTWKALQDFKEGNAIFTFPN 196 + LIIA G Q + ++ E+T F G + Sbjct: 126 TCDALIIATGAQAKWLGLES-------------------EQT------FMGGGV-----S 155 Query: 197 TPVKCAGAPQKIMYLSEAYFRKTGKRSKANIIFNTSLGAIF----GVKKYADALQEIIQE 252 C G + + T + I G + ++ Sbjct: 156 ACATCDGFFYRGKDVVVVGGGNTAVEEALYLSHIAKSVTIVHRRDGFRAEKIMQDRLLSR 215 Query: 253 RNLTVNYKKNLIEV----RADKQEAVFENLDKP----GETQVISYEMLHVTPPMSPPDVL 304 N++V + + E+ A + GETQ P V Sbjct: 216 ENVSVVWNSVIDEILGTEARPPMGATVTGVRLKNIVTGETQE-RATHGVFIAIGHAPAVS 274 Query: 305 KTSPVA--DAAGWVDVDKETLQHRRYPNVFGIGDCTNLPTSKTAAAVAAQSGILDRTISV 362 G++ ++ P +F GD T+ + A A + Sbjct: 275 LFEGKLKQKPNGYLWTAPDS-TATDVPGIFAAGDVTD-DIYRQAVTAAGMGCMAALEAER 332 Query: 363 IMKNQTP 369 + Q P Sbjct: 333 WLAAQEP 339 >4UIR-A nrPDB Length = 646 Score = 31.7 bits (70), Expect = 0.61, Method: Composition-based stats. Identities = 20/89 (22%), Positives = 37/89 (41%), Gaps = 14/89 (15%) Query: 24 TQQVGPLQLHTGASHAARNHYEVLVLGGGSGGITMAARMKR--KVGAENVAIVEPSERHF 81 + Q+G Q + G + ++ ++ ++G G G++ A R V A+N+ +E Sbjct: 43 SDQIGNYQRNKGIPVQSYDNSKIYIIGSGIAGMSAAYYFIRDGHVPAKNITFLEQ----- 97 Query: 82 YQPIWTLVGAGAKQLSSSGRPTASVIPSG 110 + G L +G PT I G Sbjct: 98 -----LHIDGG--SLDGAGNPTDGYIIRG 119 >3UKH-A nrPDB Length = 519 Score = 31.7 bits (70), Expect = 0.65, Method: Composition-based stats. Identities = 9/40 (22%), Positives = 19/40 (47%) Query: 115 KARVTELNPDKNCIHTDDDEKISYRYLIIALGIQLDYEKI 154 K +VT++N + + D I Y+ L+ + + E + Sbjct: 238 KGKVTKVNANNKTVTLQDGTTIGYKKLVSTMAVDFLAEAM 277 >5M5J-A nrPDB Length = 325 Score = 31.3 bits (69), Expect = 0.82, Method: Composition-based stats. Identities = 45/254 (17%), Positives = 83/254 (32%), Gaps = 33/254 (12%) Query: 110 GVEWIKARVTELNPDK---NCIHTDDDEKISYRYLIIALGIQLDYEKIKGLPEGFAHPKI 166 G E + V ++ +H ++E LIIA G KG E + Sbjct: 87 GAELLYEDVHSIDVSSRPFKIVHGYENETTLADALIIATGATARRLDCKGEKEYWQKGV- 145 Query: 167 GSNYSVKTVEKTWKALQDFKEGNAIFTFPNTPVKCAGAPQKIMYLSEAYFRKTGKRSKAN 226 S V + G + V C A ++ Y R K Sbjct: 146 ----SACAVCDSA-----MATGKEVVVVGGGDVACEEATYLTKIATKVYMVLR--RDK-- 192 Query: 227 IIFNTSLGAIFGVKKYADALQEIIQERNLTVNYKKNLIEVRADKQEAVFENLD--KPGET 284 + A +++++ E+ + + Y + E++ D + ++ K G+T Sbjct: 193 ------------FRASAAMVKKVMNEKLIEIIYDSAIDEIKGDGKCVTSVSIKNLKDGKT 240 Query: 285 QVISYEMLHVTPPMSP-PDVLKTSPV-ADAAGWVDVDKETLQHRRYPNVFGIGDCTNLPT 342 + ++ L+ P LK + D AG++ + Q VF GDC + Sbjct: 241 RTLNAGALYWAVGHDPQTSFLKKGQLEQDEAGYILLKDHPTQRTSVDGVFAAGDCCDHLY 300 Query: 343 SKTAAAVAAQSGIL 356 + A + S Sbjct: 301 RQAVVAAGSGSKAA 314 >6N7F-A nrPDB Length = 453 Score = 31.3 bits (69), Expect = 0.92, Method: Composition-based stats. Identities = 44/287 (15%), Positives = 93/287 (32%), Gaps = 41/287 (14%) Query: 124 DKNCIHTDDDEKISYRYLIIALGIQLDYEKIKGLPEGFAHPKIGSNYSVKTVEKTWKALQ 183 D + + + + +++IA G + I+G G + + AL Sbjct: 122 DAHTVEIA-GQLYTAPHILIATGGHPVFPDIEGAQYGISS-------------DGFFALD 167 Query: 184 DFKEGNAIFTFPNTPVKCAGAPQKIMYLSEAYFRKTGKRSKANIIFNTSLGAIFGVKKYA 243 + + A+ V ++ + A SK ++ K Sbjct: 168 EVPKRTAVVGAGYIAV-------ELAGVLHA------LGSKTDLFIRHDRPLRSFDKTIV 214 Query: 244 DALQEIIQERNLTVNYKKNLIEVRADKQEAVFENLDKPGETQVISYEMLHVTPPMSPPDV 303 D L + + ++ + +V + E++ L E +V P Sbjct: 215 DVLVDEMAVNGPRLHTHAEVAKVVKNTDESLTLYLKDGQEVEVDQLIWAIGRKPNLEGFS 274 Query: 304 LKTSPVA-DAAGWVDVDKETLQHRRYPNVFGIGDCTNLPTSKTAAAVAAQSGILDRTISV 362 L + V + G+++ D ++ ++ +GD + T AVAA + +R Sbjct: 275 LDKTGVTLNDKGYIETD--AYENTSVKGIYAVGDVNG-KLALTPVAVAAGRRLSER---- 327 Query: 363 IMKNQTPTK-KYDGYT----SCPLVTGYNRV-ILAEFDYKAEPLETF 403 + +T K Y S P++ A Y E ++T+ Sbjct: 328 LFNGKTDEKLDYQNVATVIFSHPVIGSVGLSEEAAVKQYGQEAVKTY 374 >5MIU-A nrPDB Length = 535 Score = 31.3 bits (69), Expect = 0.93, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 28/72 (38%), Gaps = 10/72 (13%) Query: 76 PSERHFYQPIWTLVGAGAKQLSSSGRPTASVIPSGVEWIKAR-VTELNPDKNCIHTDDDE 134 ++QP V A + ++ GV + + V L+ N + +D Sbjct: 121 KERSIYFQPPSFYVSA---------QDLPNIENGGVAVLTGKKVVHLDVRGNMVKLNDGS 171 Query: 135 KISYRYLIIALG 146 +I++ +IA G Sbjct: 172 QITFEKCLIATG 183 >3NTA-A nrPDB Length = 574 Score = 30.9 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 49/321 (15%), Positives = 105/321 (32%), Gaps = 45/321 (14%) Query: 44 YEVLVLGGGSGGITMAARMKRKVGAENVAIVEPSERHFY--QPIWTLVGAGAKQLSSSGR 101 ++L++GG +GG + AAR +R + + E E + + + Q S+ Sbjct: 2 KKILIIGGVAGGASAAARARRLSETAEIIMFERGEYVSFANCGLPYHISGEIAQRSALVL 61 Query: 102 PTASVIPSGVEW---IKARVTELNPDKNCIHTD---DDEKI--SYRYLIIALGIQLDYEK 153 T + +K V ++ + D + SY L+++ G Sbjct: 62 QTPESFKARFNVEVRVKHEVVAIDRAAKLVTVRRLLDGSEYQESYDTLLLSPGAAPIVPP 121 Query: 154 IKGLPEGFAHPKIGSNYSVKTVEKTWKALQDFKEGNAIFTFPNTPVKCAGAPQKIMYLSE 213 I G+ +S++ + + LQ + N G + + E Sbjct: 122 IPGVDNPLT-------HSLRNIPDMDRILQTIQMNNV------EHATVVGGGFIGLEMME 168 Query: 214 AYFRKTGKRSKANIIFNTSLGAIFGVKKYADALQEIIQERNLTVNYKKNLIEVRADKQEA 273 + K ++ ++ A + I+++ + + L EV Q Sbjct: 169 SL---HHLGIKTTLLELADQVMTPVDREMAGFAHQAIRDQGVDLRLGTALSEVSYQVQ-- 223 Query: 274 VFENLDKPGETQVISYEMLHVTPPMSPPDVLKT------------SPVADAAGWVD---- 317 D GE + H++ +S ++L+T + +A AG Sbjct: 224 THVASDAAGEDTAHQHIKGHLSLTLSNGELLETDLLIMAIGVRPETQLARDAGLAIGELG 283 Query: 318 -VDKETLQHRRYPNVFGIGDC 337 + + P ++ +GD Sbjct: 284 GIKVNAMMQTSDPAIYAVGDA 304 >1JNS-A nrPDB Length = 92 Score = 30.9 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 10/55 (18%), Positives = 22/55 (40%) Query: 148 QLDYEKIKGLPEGFAHPKIGSNYSVKTVEKTWKALQDFKEGNAIFTFPNTPVKCA 202 +L + ++ + G K+ +S+ K L +F++G + F C Sbjct: 15 KLALDLLEQIKNGADFGKLAKKHSICPSGKRGGDLGEFRQGQMVPAFDKVVFSCP 69 >2R9Z-A nrPDB Length = 463 Score = 30.5 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 24/114 (21%), Positives = 47/114 (41%), Gaps = 10/114 (8%) Query: 34 TGASHAARNHYEVLVLGGGSGGITMAARMKRKVGAENVAIVEPSERHFYQPIWTLVGAGA 93 G + V ++G G GI +A + R G+ V +V +R +Q L+ A Sbjct: 157 DGFFALQQQPKRVAIIGAGYIGIELAG-LLRSFGS-EVTVVALEDRLLFQ-FDPLLSA-- 211 Query: 94 KQLSSSGRPTASVIPSGVEWIKARVTELNPDKNCIHTDDDEKI-SYRYLIIALG 146 L+ + A I + +E+ A + + + D ++ + +I A+G Sbjct: 212 -TLAENMH--AQGIETHLEFAVAALER-DAQGTTLVAQDGTRLEGFDSVIWAVG 261 >2EQ6-A nrPDB Length = 464 Score = 30.5 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 59/356 (16%), Positives = 107/356 (30%), Gaps = 53/356 (14%) Query: 19 LLRLGTQQVGPLQLHTGASHAARNHYEVLVLGGGSGG-------ITMAARMKRKVGAENV 71 L+ +GT GP H A + V G GG I A + ++ Sbjct: 9 LIVIGT---GPGGYHAAIRAAQLGLKVLAVEAGEVGGVCLNVGCIPTKALLHAAETLHHL 65 Query: 72 AIVEPSERHFYQPIWTLVGAGAKQ--LSSSGRPTASVIP-SGVEWIKARVTELNPDKNCI 128 + E + G + + +++ +GVE ++ + P + + Sbjct: 66 KVAEGFGLKAKPELDLKKLGGWRDQVVKKLTGGVGTLLKGNGVELLRGFARLVGPKEVEV 125 Query: 129 HTDDDEKISYRYLIIALGIQLDYEKIKGLPEGFAHPKIGSNYSVKTVEKTWKALQDFKEG 188 E+ + LI+A G + ++KG P F S ++K E K L G Sbjct: 126 ---GGERYGAKSLILATGSEPL--ELKGFP--FGEDVWDSTRALKVEEGLPKRLLVI-GG 177 Query: 189 NAIFTFPNTPVKCAGAPQKIMYLSEAYFRKTGKRSKANIIFNTSLGAIF--GVKKYADAL 246 A+ + +R A + + I G + A L Sbjct: 178 GAVGL---------------------ELGQVYRRLGAEVTLIEYMPEILPQGDPETAALL 216 Query: 247 QEIIQERNLTVNYKKNLIEVRADKQEAVFENLDKPGETQVISYEMLHVT----PPMSPPD 302 + +++ + V K + K G + P + Sbjct: 217 RRALEKEGIRVRTKTKAVGYEKKKDGLHVRLEPAEGGEGEEVVVDKVLVAVGRKPRTEGL 276 Query: 303 VLKTSPV-ADAAGWVDVDKETLQHRRYPNVFGIGDCTNLPTSKTAAAVAAQSGILD 357 L+ + V D G++ V+ P V+ IGD P A + I Sbjct: 277 GLEKAGVKVDERGFIRVNARMETSV--PGVYAIGDAARPPL--LAHKAMREGLIAA 328 >2DWU-A nrPDB Length = 276 Score = 30.1 bits (66), Expect = 2.0, Method: Composition-based stats. Identities = 14/46 (30%), Positives = 25/46 (54%) Query: 43 HYEVLVLGGGSGGITMAARMKRKVGAENVAIVEPSERHFYQPIWTL 88 H + VL G GG+T+A+ + R++ E++ + +ER Y P Sbjct: 7 HSVIGVLDSGVGGLTVASEIIRQLPKESICYIGDNERCPYGPRSVE 52 >4Z44-A nrPDB Length = 554 Score = 30.1 bits (66), Expect = 2.1, Method: Composition-based stats. Identities = 13/65 (20%), Positives = 28/65 (43%), Gaps = 8/65 (12%) Query: 36 ASHAARNHYEVLVLGGGSGGITMAARMKRKVGAE-NVAIVEPSERHFYQPIWTLVGAGAK 94 SH + ++++GGG+ G A+ + R + + N+ ++E +G G Sbjct: 14 GSHMNKPIKNIVIVGGGTAGWMAASYLVRALQQQANITLIES-------AAIPRIGVGEA 66 Query: 95 QLSSS 99 + S Sbjct: 67 TIPSL 71 >3LOV-A nrPDB Length = 475 Score = 30.1 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 10/37 (27%), Positives = 19/37 (51%) Query: 43 HYEVLVLGGGSGGITMAARMKRKVGAENVAIVEPSER 79 ++++GGG G+ A +R N+ ++E ER Sbjct: 4 SKRLVIVGGGITGLAAAYYAERAFPDLNITLLEAGER 40 >5MLK-A nrPDB Length = 614 Score = 29.7 bits (65), Expect = 2.6, Method: Composition-based stats. Identities = 21/167 (12%), Positives = 42/167 (25%), Gaps = 24/167 (14%) Query: 236 IFGVKKYADALQEIIQERNLTVNYKKNLIEVRAD--------KQEAVFENLDKPGETQVI 287 + DA + R + + + ++ V +D + Sbjct: 449 VSDPAFIGDANGFSVHTRWIETEWNNTIEPFTDGEPLDEDARPRQKVVVEIDGRRVEVSL 508 Query: 288 SYEMLHVTPPMSPPDVLKTSPVADAAGWVDVDKETLQHRRYPNVFGIGDCTNLPTSKTAA 347 ++ L D G + + + + GD P T Sbjct: 509 PADL-----------ALSNGGGCDPVGVIRRKPKPRKRGAHTGAAASGDAVTAPMQGTVV 557 Query: 348 AVAAQSG---ILDRTISVI--MKNQTPTKKYDGYTSCPLVTGYNRVI 389 A + G + + V+ MK + P + T L I Sbjct: 558 KFAVEEGQEVVAGDLVVVLEAMKMENPVTAHKDGTITGLAVEAGAAI 604 >4G2C-A nrPDB Length = 493 Score = 29.3 bits (64), Expect = 3.4, Method: Composition-based stats. Identities = 10/47 (21%), Positives = 15/47 (31%), Gaps = 3/47 (6%) Query: 296 PPMSPPDVLKTSPVADAAGWVDVDKETLQHRRYPNVFGIGDCTNLPT 342 P + +AD A + E + V +GD T P Sbjct: 135 PSFTAGAKAAVEKLADPA---VTEWEGHYQQTIDAVLLLGDATAGPV 178 >3RBN-A nrPDB Length = 284 Score = 29.3 bits (64), Expect = 3.8, Method: Composition-based stats. Identities = 14/105 (13%), Positives = 36/105 (34%), Gaps = 4/105 (3%) Query: 222 RSKANIIFNTSLGAIFGVKKYADALQEIIQERNLTVNYKKNLIEVRADKQEAVFENLDKP 281 S+ +F+ ++ A+ + ++ +E + + E +D+ Sbjct: 109 LSEPAPLFDLAMLALDSP-ESGWTEEDGPKEGLAEYIVEFLKKKAEMLADYFSLE-IDEE 166 Query: 282 GETQVISYEMLHVTPPMSPPDVLKTSPVADAAGWVDVDKETLQHR 326 G + + + PP+ + +A W D +KE + Sbjct: 167 GNLIGLPLLIDNYVPPLEGLPIF-ILRLATEVNW-DEEKECFESL 209 >3O4F-A nrPDB Length = 294 Score = 29.0 bits (63), Expect = 4.6, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 28/81 (34%), Gaps = 8/81 (9%) Query: 44 YEVLVLGGGSGGITMAARMKRKVGAENVAIVE--PSERHFYQPIWTLVGAGAKQLSSSGR 101 VL++GGG G + + R E++ +VE F + AG Sbjct: 85 KHVLIIGGGDGAM--LREVTRHKNVESITMVEIDAGVVSFCRQYLPNHNAG--SYDDPRF 140 Query: 102 PTASVIPSGVEWIKARVTELN 122 VI GV ++ + Sbjct: 141 KL--VIDDGVNFVNQTSQTFD 159 >5ZHA-A nrPDB Length = 275 Score = 29.0 bits (63), Expect = 4.7, Method: Composition-based stats. Identities = 8/77 (10%), Positives = 24/77 (31%), Gaps = 2/77 (2%) Query: 63 KRKVGAENVAIVEPSERHFYQ--PIWTLVGAGAKQLSSSGRPTASVIPSGVEWIKARVTE 120 KR +V +E ++ +W + + S + +++I + T Sbjct: 165 KRWFVTSEGCLVYLAEDFGFKSLYLWPINSDSERSPSMMRHAINQMRSHKIKFIFSESTN 224 Query: 121 LNPDKNCIHTDDDEKIS 137 + + + + Sbjct: 225 SDQPAKQVAYETNASYG 241 >2GMH-A nrPDB Length = 584 Score = 28.6 bits (62), Expect = 6.2, Method: Composition-based stats. Identities = 10/37 (27%), Positives = 19/37 (51%), Gaps = 4/37 (10%) Query: 44 YEVLVLGGGSGGITMAARMKRKVGAEN----VAIVEP 76 +V+++G G G++ A R+K+ V +VE Sbjct: 36 ADVVIVGAGPAGLSAATRLKQLAAQHEKDLRVCLVEK 72 >2GAG-B nrPDB Length = 405 Score = 28.2 bits (61), Expect = 8.3, Method: Composition-based stats. Identities = 12/41 (29%), Positives = 23/41 (56%) Query: 36 ASHAARNHYEVLVLGGGSGGITMAARMKRKVGAENVAIVEP 76 A+ + Y+ +++GGG G+ A + + G NVA++E Sbjct: 14 ANPEPKKSYDAIIVGGGGHGLATAYFLAKNHGITNVAVLEK 54 >1XJ5-A nrPDB Length = 334 Score = 27.8 bits (60), Expect = 9.2, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 30/81 (37%), Gaps = 9/81 (11%) Query: 42 NHYEVLVLGGGSGGITMAARMKRKVGAENVAI--VEPSERHFYQPIWTLVGAGAKQLSSS 99 N +VLV+GGG GG+ + R E + + ++ + + V G Sbjct: 120 NPKKVLVIGGGDGGV--LREVARHASIEQIDMCEIDKMVVDVSKQFFPDVAIG---YEDP 174 Query: 100 GRPTASVIPSGVEWIKARVTE 120 VI GV ++K Sbjct: 175 RVNL--VIGDGVAFLKNAAEG 193 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.313 0.126 0.318 Lambda K H 0.267 0.0389 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,324,257 Number of Sequences: 36641 Number of extensions: 580213 Number of successful extensions: 2107 Number of sequences better than 10.0: 80 Number of HSP's better than 10.0 without gapping: 57 Number of HSP's successfully gapped in prelim test: 72 Number of HSP's that attempted gapping in prelim test: 1964 Number of HSP's gapped (non-prelim): 150 length of query: 450 length of database: 10,336,785 effective HSP length: 100 effective length of query: 350 effective length of database: 6,672,685 effective search space: 2335439750 effective search space used: 2335439750 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.5 bits) S2: 61 (28.2 bits)