BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9Y5K2 (254 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2BDH-A nrPDB 456 e-129 2PSX-A nrPDB 245 1e-65 3BSQ-A nrPDB 212 1e-55 1NPM-A nrPDB 201 2e-52 5ZFH-A nrPDB 197 3e-51 5MS3-A nrPDB 191 4e-49 1SGF-G nrPDB 187 3e-48 1AO5-A nrPDB 186 1e-47 3QUM-P nrPDB 185 2e-47 6QHB-A nrPDB 184 4e-47 4NFE-A nrPDB 183 7e-47 1TON-A nrPDB 180 4e-46 5FXL-A nrPDB 180 5e-46 1SPJ-A nrPDB 176 7e-45 1A0J-A nrPDB 173 7e-44 4AN7-A nrPDB 173 8e-44 1UTJ-A nrPDB 172 9e-44 4WWY-A nrPDB 172 1e-43 1SGF-A nrPDB 169 1e-42 5C67-A nrPDB 168 2e-42 1F7Z-A nrPDB 167 3e-42 2TLD-E nrPDB 167 4e-42 1GVZ-A nrPDB 164 4e-41 2EEK-A nrPDB 158 3e-39 4GSO-A nrPDB 156 8e-39 1OP0-A nrPDB 152 1e-37 1FXY-A nrPDB 151 2e-37 5LPF-A nrPDB 147 3e-36 2AIQ-A nrPDB 147 3e-36 1EUF-A nrPDB 146 9e-36 2ZKS-A nrPDB 146 1e-35 4E7N-A nrPDB 144 3e-35 3S69-A nrPDB 144 3e-35 3G01-A nrPDB 142 2e-34 1MZD-A nrPDB 141 2e-34 3S9B-A nrPDB 140 4e-34 1FDP-A nrPDB 138 2e-33 1NN6-A nrPDB 138 2e-33 1BQY-A nrPDB 134 3e-32 5XRF-A nrPDB 134 4e-32 1KYN-A nrPDB 133 6e-32 1IAU-A nrPDB 132 2e-31 5FCR-A nrPDB 131 4e-31 1FI8-A nrPDB 130 5e-31 4Q7Y-A nrPDB 130 7e-31 1ORF-A nrPDB 128 2e-30 1BRU-P nrPDB 128 2e-30 1PYT-D nrPDB 127 3e-30 3TK9-A nrPDB 127 4e-30 4H4F-A nrPDB 127 4e-30 2CGA-A nrPDB 126 8e-30 3DFJ-A nrPDB 125 2e-29 3E0N-B nrPDB 125 2e-29 1AZZ-A nrPDB 124 4e-29 1X7A-C nrPDB 124 5e-29 5TJX-A nrPDB 122 1e-28 4DGJ-A nrPDB 121 3e-28 3LC3-A nrPDB 119 9e-28 1KIG-H nrPDB 119 1e-27 2RDL-A nrPDB 119 1e-27 4MPW-A nrPDB 118 2e-27 6I44-A nrPDB 116 8e-27 1LTO-A nrPDB 116 9e-27 5LHN-A nrPDB 116 1e-26 1AE5-A nrPDB 115 1e-26 2F91-A nrPDB 115 2e-26 3F6U-H nrPDB 115 2e-26 1EKB-B nrPDB 114 3e-26 5GVT-A nrPDB 114 4e-26 3K65-B nrPDB 113 6e-26 3NXP-A nrPDB 113 7e-26 2OLG-A nrPDB 113 8e-26 2XXL-A nrPDB 112 1e-25 4NZQ-A nrPDB 112 1e-25 3P8G-A nrPDB 112 2e-25 1FUJ-A nrPDB 112 2e-25 3W94-A nrPDB 112 2e-25 1YC0-A nrPDB 112 2e-25 2PKA-B nrPDB 111 3e-25 2OCV-B nrPDB 111 3e-25 2R0L-A nrPDB 111 4e-25 1FON-A nrPDB 110 5e-25 5UGG-A nrPDB 110 6e-25 1C5M-D nrPDB 110 6e-25 1PPF-E nrPDB 109 1e-24 5TO3-B nrPDB 108 2e-24 1MKW-K nrPDB 108 2e-24 1SC8-U nrPDB 108 2e-24 1ETT-H nrPDB 108 2e-24 5O32-I nrPDB 107 3e-24 1P57-B nrPDB 107 4e-24 4IGD-A nrPDB 107 5e-24 3T2N-A nrPDB 107 5e-24 4DUR-A nrPDB 106 8e-24 1VR1-H nrPDB 106 9e-24 4Z6A-H nrPDB 106 1e-23 2XRC-A nrPDB 105 1e-23 4DJZ-B nrPDB 105 2e-23 6AOD-C nrPDB 105 2e-23 4BXW-A nrPDB 103 7e-23 3RP2-A nrPDB 103 7e-23 2OQ5-A nrPDB 102 1e-22 2F83-A nrPDB 102 2e-22 4LK4-A nrPDB 100 6e-22 2B9L-A nrPDB 99 2e-21 5XW8-A nrPDB 97 1e-20 4XDE-A nrPDB 97 1e-20 5KWM-A nrPDB 96 1e-20 1FIZ-A nrPDB 96 2e-20 1A5I-A nrPDB 95 2e-20 1ZJK-A nrPDB 95 3e-20 1Q3X-A nrPDB 94 4e-20 4FXG-H nrPDB 94 7e-20 4IW4-E nrPDB 93 1e-19 1FIW-A nrPDB 92 2e-19 1BDA-A nrPDB 92 3e-19 1PQ7-A nrPDB 91 4e-19 5UBM-A nrPDB 91 7e-19 4KKD-A nrPDB 90 1e-18 1ELV-A nrPDB 89 1e-18 1ELT-A nrPDB 88 4e-18 2V35-A nrPDB 87 5e-18 4J1Y-A nrPDB 87 5e-18 1EQ9-A nrPDB 87 5e-18 4X0L-C nrPDB 87 6e-18 4WJG-C nrPDB 87 8e-18 1AKS-B nrPDB 86 1e-17 1YM0-A nrPDB 86 1e-17 2HLC-A nrPDB 84 8e-17 2ASU-B nrPDB 83 1e-16 1SI5-H nrPDB 82 2e-16 6BQM-A nrPDB 79 2e-15 4F4O-C nrPDB 75 2e-14 3I77-A nrPDB 75 3e-14 3VGC-B nrPDB 75 3e-14 3H7T-A nrPDB 74 6e-14 3BEU-A nrPDB 71 3e-13 2KAI-A nrPDB 69 3e-12 2FMJ-A nrPDB 66 1e-11 2JET-B nrPDB 65 4e-11 2HNT-F nrPDB 62 2e-10 1BBR-E nrPDB 62 2e-10 1RIW-B nrPDB 61 4e-10 3H7O-A nrPDB 60 1e-09 2QY0-B nrPDB 60 1e-09 1GPZ-A nrPDB 60 1e-09 2JET-C nrPDB 59 2e-09 1MD7-A nrPDB 59 3e-09 1EPT-B nrPDB 59 3e-09 1BBR-H nrPDB 58 3e-09 2OK5-A nrPDB 58 5e-09 3RU4-E nrPDB 57 6e-09 1DLE-A nrPDB 57 6e-09 2WIN-I nrPDB 57 7e-09 1M9U-A nrPDB 55 2e-08 2I6S-A nrPDB 44 5e-05 2HNT-C nrPDB 40 7e-04 3H5C-B nrPDB 40 9e-04 3F1S-B nrPDB 40 0.001 1H2B-A nrPDB 29 2.2 5JM5-A nrPDB 27 5.9 >2BDH-A nrPDB Length = 223 Score = 456 bits (1174), Expect = e-129, Method: Compositional matrix adjust. Identities = 222/223 (99%), Positives = 222/223 (99%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ Sbjct: 1 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 60 Query: 91 EPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLV 150 EPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLV Sbjct: 61 EPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLV 120 Query: 151 SGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDSGGP 210 SGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGG DQKDSCNGDSGGP Sbjct: 121 SGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGQDQKDSCNGDSGGP 180 Query: 211 LICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQA 253 LICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQA Sbjct: 181 LICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQA 223 >2PSX-A nrPDB Length = 227 Score = 245 bits (626), Expect = 1e-65, Method: Compositional matrix adjust. Identities = 117/227 (51%), Positives = 159/227 (70%), Gaps = 4/227 (1%) Query: 31 IINGEDCSPHSQPWQAALVME-NELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEAD 89 IING DC H+QPWQAAL++ N+L+C VLVHPQW+L+AAHC + + + LG +SL Sbjct: 1 IINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPV 60 Query: 90 QEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCL 149 E G QM + S+ HP Y+ P +NDLMLIKL+ + + +R I+++S CP+AG CL Sbjct: 61 YESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCL 120 Query: 150 VSGWGLLANGRM--PTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDS 207 VSGWG + ++ P VLQC+N+SV+S++ C Y +MFCAG +DSC GDS Sbjct: 121 VSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAG-RDSCQGDS 179 Query: 208 GGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 GGP++CNG LQGLVS+G PC + PGVYTNLCKFT+WI++T+QA+ Sbjct: 180 GGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 226 >3BSQ-A nrPDB Length = 227 Score = 212 bits (540), Expect = 1e-55, Method: Compositional matrix adjust. Identities = 106/224 (47%), Positives = 145/224 (64%), Gaps = 5/224 (2%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 II+G C+ S PWQ AL+ N+L C GVLV+ +WVL+AAHC N YT+ LG +L D+ Sbjct: 1 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTL-GDR 59 Query: 91 EPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLV 150 +Q ++AS S RHP Y+ NDLML+KL+ S ++ + + S+C G +C V Sbjct: 60 R--AQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTV 117 Query: 151 SGWGLLA--NGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDSG 208 SGWG + P+ L CV+V ++S + C+K+Y L SM CAG +K++CNGDSG Sbjct: 118 SGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSG 177 Query: 209 GPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 252 GPL+C G LQGLVS+G PCGQ PGVYT +CKFT+WI T++ Sbjct: 178 GPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 221 >1NPM-A nrPDB Length = 225 Score = 201 bits (512), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 96/226 (42%), Positives = 141/226 (62%), Gaps = 7/226 (3%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 I+ G +C PHSQPWQAAL L C GVLV +WVL+AAHC + Y++ LG HSL++ Sbjct: 1 ILEGRECIPHSQPWQAALFQGERLICGGVLVGDRWVLTAAHCKKQKYSVRLGDHSLQSRD 60 Query: 91 EPGSQMVEASLSVRHPEYNR---PLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNS 147 +P Q ++ + S++HP YN ++D+MLI+L S + D ++ + +A+ CP G Sbjct: 61 QP-EQEIQVAQSIQHPCYNNSNPEDHSHDIMLIRLQNSANLGDKVKPVQLANLCPKVGQK 119 Query: 148 CLVSGWGLLANGR--MPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNG 205 C++SGWG + + + P L C V + S+ C + Y M CAG + D+C G Sbjct: 120 CIISGWGTVTSPQENFPNTLNCAEVKIYSQNKCERAYPGKITEGMVCAGSSNG-ADTCQG 178 Query: 206 DSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 251 DSGGPL+C+G LQG+ S+G PCG+ PGVYT +C++T WI+KT+ Sbjct: 179 DSGGPLVCDGMLQGITSWGSDPCGKPEKPGVYTKICRYTTWIKKTM 224 >5ZFH-A nrPDB Length = 224 Score = 197 bits (502), Expect = 3e-51, Method: Compositional matrix adjust. Identities = 98/225 (43%), Positives = 134/225 (59%), Gaps = 5/225 (2%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 II+G C S PWQ AL+ N+L C GVLV WVL+AAHC Y + LG + DQ Sbjct: 1 IIDGYKCKEGSHPWQVALLKGNQLHCGGVLVDKYWVLTAAHCKMGQYQVQLGSDKI-GDQ 59 Query: 91 EPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLV 150 +Q ++A+ S RHP Y+ ND+ML++LDE V S + ++ + C G SC V Sbjct: 60 S--AQKIKATKSFRHPGYSTKTHVNDIMLVRLDEPVKMSSKVEAVQLPEHCEPPGTSCTV 117 Query: 151 SGWGLLA--NGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDSG 208 SGWG + P+ L C +V ++S C K+Y L +M CAG + ++CNGDSG Sbjct: 118 SGWGTTTSPDVTFPSDLMCSDVKLISSRECKKVYKDLLGKTMLCAGIPDSKTNTCNGDSG 177 Query: 209 GPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQA 253 GPL+CN LQGLVS+G PCGQ PGVYT +CK+ W+ +T++ Sbjct: 178 GPLVCNDTLQGLVSWGTYPCGQPNDPGVYTQVCKYKRWVMETMKT 222 >5MS3-A nrPDB Length = 228 Score = 191 bits (484), Expect = 4e-49, Method: Compositional matrix adjust. Identities = 96/226 (42%), Positives = 131/226 (57%), Gaps = 7/226 (3%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 ++ G +C PHSQPWQAAL +L C GVLV WVL+AAHC + YT+ LG HSL+ Sbjct: 1 VLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQNKD 60 Query: 91 EPGSQMVEASLSVRHPEYNRPLLAN---DLMLIKLDESVSESDTIRSISIASQCPTAGNS 147 P Q + S+ HP YN + + DLML++L + S ++ IS+A C G Sbjct: 61 GP-EQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPGQK 119 Query: 148 CLVSGWGLLANGR--MPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNG 205 C VSGWG + + R P L C V + ++ C Y M CAG D+C G Sbjct: 120 CTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKG-ADTCQG 178 Query: 206 DSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 251 DSGGPL+C+G LQG+ S+G PCG+ PGVYTN+C++ +WI+K + Sbjct: 179 DSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKII 224 >1SGF-G nrPDB Length = 237 Score = 187 bits (476), Expect = 3e-48, Method: Compositional matrix adjust. Identities = 94/234 (40%), Positives = 140/234 (59%), Gaps = 14/234 (5%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 I+ G C +SQPW A+ + C GVL+ P WVL+AAHC+ ++Y + LG ++L D Sbjct: 1 IVGGFKCEKNSQPWHVAVYRYTQYLCGGVLLDPNWVLTAAHCYDDNYKVWLGKNNLFKD- 59 Query: 91 EPGSQMVEASLSVRHPEYNRPLL-----------ANDLMLIKLDESVSESDTIRSISIAS 139 EP +Q S ++ HP +N L+ +NDLML++L + +DT++ I++ + Sbjct: 60 EPSAQHRFVSKAIPHPGFNMSLMRKHIRFLEYDYSNDLMLLRLSKPADITDTVKPITLPT 119 Query: 140 QCPTAGNSCLVSGWGLLANGRMPTV--LQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGH 197 + P G++CL SGWG + + L CVN+ ++ E C+K + +M CAG Sbjct: 120 EEPKLGSTCLASGWGSITPTKFQFTDDLYCVNLKLLPNEDCAKAHIEKVTDAMLCAGEMD 179 Query: 198 DQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 251 KD+C GDSGGPLIC+G LQG+ S+G PCG+ +PGVYT L KFT WI+ T+ Sbjct: 180 GGKDTCKGDSGGPLICDGVLQGITSWGHTPCGEPDMPGVYTKLNKFTSWIKDTM 233 >1AO5-A nrPDB Length = 237 Score = 186 bits (471), Expect = 1e-47, Method: Compositional matrix adjust. Identities = 95/237 (40%), Positives = 138/237 (58%), Gaps = 14/237 (5%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 ++ G +C +SQPWQ A+ + E C GVL+ WVL+AAHC+ + Y + LG + L + Sbjct: 1 VVGGFNCEKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKL-FQE 59 Query: 91 EPGSQMVEASLSVRHPEYNRPLL-----------ANDLMLIKLDESVSESDTIRSISIAS 139 EP +Q S S HP +N LL ++DLML++L + +D ++ I++ + Sbjct: 60 EPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSDDLMLLRLSKPADITDVVKPIALPT 119 Query: 140 QCPTAGNSCLVSGWGLLANGR--MPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGH 197 + P G+ CL SGWG + R P LQCV ++++ E C+K+Y M CAG Sbjct: 120 KEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMG 179 Query: 198 DQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 KD+C DSGGPLIC+G LQG S+G PCG+ GVP +YTNL KF WI+ T+ + Sbjct: 180 GGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 236 >3QUM-P nrPDB Length = 237 Score = 185 bits (469), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 95/237 (40%), Positives = 135/237 (56%), Gaps = 14/237 (5%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 I+ G +C HSQPWQ + C GVLVHPQWVL+AAHC +N I LG HSL + Sbjct: 1 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 60 Query: 91 EPGSQMVEASLSVRHPEYNRPLLAN-----------DLMLIKLDESVSESDTIRSISIAS 139 + G Q+ + S S HP Y+ LL N DLML++L E +D ++ + + + Sbjct: 61 DTG-QVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPT 119 Query: 140 QCPTAGNSCLVSGWGLLANGRM--PTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGH 197 Q P G +C SGWG + P LQCV++ V+S +VC++++ M CAG Sbjct: 120 QEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWT 179 Query: 198 DQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 K +C+GDSGGPL+CNG LQG+ S+G PC P +YT + + +WI+ T+ A+ Sbjct: 180 GGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 236 >6QHB-A nrPDB Length = 223 Score = 184 bits (466), Expect = 4e-47, Method: Compositional matrix adjust. Identities = 93/224 (41%), Positives = 129/224 (57%), Gaps = 1/224 (0%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 +++G C S P+QAAL L C GVL+HP WVL+AAHC + + + LG H+L Q Sbjct: 1 LVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNL-GQQ 59 Query: 91 EPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLV 150 E + +V HP+Y+ D+ML++L S+ I+ + + C SC + Sbjct: 60 ESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSAQTTSCHI 119 Query: 151 SGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDSGGP 210 GWG A+G P +QC + +VS E C Y +M CAG KDSC GDSGGP Sbjct: 120 LGWGKTADGDFPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDSCQGDSGGP 179 Query: 211 LICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 L+C +L+GLVS+G PCG PGVYTN+C++T WI+KT+QA Sbjct: 180 LVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQAK 223 >4NFE-A nrPDB Length = 237 Score = 183 bits (464), Expect = 7e-47, Method: Compositional matrix adjust. Identities = 95/237 (40%), Positives = 135/237 (56%), Gaps = 14/237 (5%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 I+ G +C HSQPWQ A+ C GVLVHPQWVL+AAHC + + + LG H+L + Sbjct: 1 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 60 Query: 91 EPGSQMVEASLSVRHPEYNRPLL-----------ANDLMLIKLDESVSESDTIRSISIAS 139 + G Q V S S HP YN LL ++DLML++L E +D ++ + + + Sbjct: 61 DTG-QRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPT 119 Query: 140 QCPTAGNSCLVSGWGLLANGRM--PTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGH 197 Q P G +C SGWG + P LQCV++ ++S ++C++ Y M CAG Sbjct: 120 QEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWT 179 Query: 198 DQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 KD+C GDSGGPL+CNG LQG+ S+G PC P VYT + + +WI+ T+ A+ Sbjct: 180 GGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 236 >1TON-A nrPDB Length = 235 Score = 180 bits (457), Expect = 4e-46, Method: Compositional matrix adjust. Identities = 97/238 (40%), Positives = 135/238 (56%), Gaps = 18/238 (7%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 I+ G C +SQPWQ A++ NE C GVL+ P WV++AAHC+ N+Y + LG ++L D Sbjct: 1 IVGGYKCEKNSQPWQVAVI--NEYLCGGVLIDPSWVITAAHCYSNNYQVLLGRNNLFKD- 57 Query: 91 EPGSQMVEASLSVRHPEYNRPLL------------ANDLMLIKLDESVSESDTIRSISIA 138 EP +Q S RHP+Y PL+ +NDLML+ L E + ++ I + Sbjct: 58 EPFAQRRLVRQSFRHPDY-IPLIVTNDTEQPVHDHSNDLMLLHLSEPADITGGVKVIDLP 116 Query: 139 SQCPTAGNSCLVSGWGLLANGRMPTV--LQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGG 196 ++ P G++CL SGWG M LQCVN+ ++S E C + Y M CAG Sbjct: 117 TKEPKVGSTCLASGWGSTNPSEMVVSHDLQCVNIHLLSNEKCIETYKDNVTDVMLCAGEM 176 Query: 197 HDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 KD+C GDSGGPLIC+G LQG+ S G PC + P +Y L KFT WI+K ++ + Sbjct: 177 EGGKDTCAGDSGGPLICDGVLQGITSGGATPCAKPKTPAIYAKLIKFTSWIKKVMKEN 234 >5FXL-A nrPDB Length = 246 Score = 180 bits (457), Expect = 5e-46, Method: Compositional matrix adjust. Identities = 95/246 (38%), Positives = 142/246 (57%), Gaps = 5/246 (2%) Query: 11 FLGYLILGVAGSLVSGSCSQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAA 70 F+ +LG A + +I+ G C ++ P+Q +L FC G L++ QWV+SAA Sbjct: 4 FIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSL-NSGYHFCGGSLINSQWVVSAA 62 Query: 71 HCFQNSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESD 130 HC+++ + LG ++ E Q + AS S+ HP YN L ND+MLIKL + S + Sbjct: 63 HCYKSGIQVRLGEDNINV-VEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNS 121 Query: 131 TIRSISIASQCPTAGNSCLVSGWGLLANG--RMPTVLQCVNVSVVSEEVCSKLYDPLYHP 188 + SIS+ + C +AG CL+SGWG + P VL+C+ ++S+ C Y Sbjct: 122 RVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITS 181 Query: 189 SMFCAGGGHDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIE 248 +MFCAG KDSC GDSGGP++C+G LQG+VS+G C Q PGVYT +C + WI+ Sbjct: 182 NMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSG-CAQKNKPGVYTKVCNYVSWIK 240 Query: 249 KTVQAS 254 +T+ ++ Sbjct: 241 QTIASN 246 >1SPJ-A nrPDB Length = 238 Score = 176 bits (447), Expect = 7e-45, Method: Compositional matrix adjust. Identities = 94/235 (40%), Positives = 132/235 (56%), Gaps = 15/235 (6%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 I+ G +C HSQPWQAAL + C G+LVH QWVL+AAHC ++Y + LG H+L D Sbjct: 1 IVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAAHCISDNYQLWLGRHNL-FDD 59 Query: 91 EPGSQMVEASLSVRHPEYNRPLLAN-----------DLMLIKLDESVSE-SDTIRSISIA 138 E +Q V S S HP +N LL N DLML++L E +D ++ + + Sbjct: 60 ENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKVVELP 119 Query: 139 SQCPTAGNSCLVSGWGLLA--NGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGG 196 ++ P G++CL SGWG + N P LQCV++ ++ + C K + M C G Sbjct: 120 TEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQKVTDFMLCVGHL 179 Query: 197 HDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 251 KD+C GDSGGPL+C+G LQG+ S+G PCG P V + + +WIE T+ Sbjct: 180 EGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWIEDTI 234 >1A0J-A nrPDB Length = 223 Score = 173 bits (438), Expect = 7e-44, Method: Compositional matrix adjust. Identities = 89/226 (39%), Positives = 135/226 (59%), Gaps = 5/226 (2%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 I+ G +C +S +QA+L FC G L+ WV+SAAHC+++ + LG H++ A Sbjct: 1 IVGGYECRKNSASYQASL-QSGYHFCGGSLISSTWVVSAAHCYKSRIQVRLGEHNI-AVN 58 Query: 91 EPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLV 150 E Q +++ + HP YN L ND+MLIKL + S + + ++++ S C ++G CLV Sbjct: 59 EGTEQFIDSVKVIMHPSYNSRNLDNDIMLIKLSKPASLNSYVSTVALPSSCASSGTRCLV 118 Query: 151 SGWGLLA--NGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDSG 208 SGWG L+ + P L+C+++ ++S C+ Y +MFCAG KDSC GDSG Sbjct: 119 SGWGNLSGSSSNYPDTLRCLDLPILSSSSCNSAYPGQITSNMFCAGFMEGGKDSCQGDSG 178 Query: 209 GPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 GP++CNG LQG+VS+G C Q PGVYT +C + WI T+ ++ Sbjct: 179 GPVVCNGQLQGVVSWGYG-CAQRNKPGVYTKVCNYRSWISSTMSSN 223 >4AN7-A nrPDB Length = 231 Score = 173 bits (438), Expect = 8e-44, Method: Compositional matrix adjust. Identities = 88/227 (38%), Positives = 133/227 (58%), Gaps = 5/227 (2%) Query: 30 QIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEAD 89 +I+ G C+ +S P+Q +L FC G L++ QWV+SAAHC+++ + LG H+++ Sbjct: 8 KIVGGYTCAANSIPYQVSL-NSGSHFCGGSLINSQWVVSAAHCYKSRIQVRLGEHNIDV- 65 Query: 90 QEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCL 149 E Q + A+ + HP +N L ND+MLIKL + + + ++S+ C AG CL Sbjct: 66 LEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRSCAAAGTECL 125 Query: 150 VSGWGLL--ANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDS 207 +SGWG + P++LQC+ V+S+ C Y +M C G KDSC GDS Sbjct: 126 ISGWGNTKSSGSSYPSLLQCLKAPVLSDSSCKSSYPGQITGNMICVGFLEGGKDSCQGDS 185 Query: 208 GGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 GGP++CNG LQG+VS+G C Q PGVYT +C + WI++T+ A+ Sbjct: 186 GGPVVCNGQLQGIVSWGYG-CAQKNKPGVYTKVCNYVNWIQQTIAAN 231 >1UTJ-A nrPDB Length = 242 Score = 172 bits (437), Expect = 9e-44, Method: Compositional matrix adjust. Identities = 88/225 (39%), Positives = 137/225 (60%), Gaps = 4/225 (1%) Query: 30 QIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEAD 89 +I+ G +C P+SQP Q +L FC G LV+ WV+SAAHC+++ + LG H+++ Sbjct: 20 KIVGGYECKPYSQPHQVSL-NSGYHFCGGSLVNENWVVSAAHCYKSRVEVRLGEHNIKV- 77 Query: 90 QEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCL 149 E Q + +S +RHP Y+ + ND+MLIKL + + + ++ +++ + C AG C Sbjct: 78 TEGSEQFISSSRVIRHPNYSSYNIDNDIMLIKLSKPATLNTYVQPVALPTSCAPAGTMCT 137 Query: 150 VSGWG-LLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDSG 208 VSGWG +++ LQC+N+ ++S C+ Y + +MFCAG KDSC GDSG Sbjct: 138 VSGWGNTMSSTADSNKLQCLNIPILSYSDCNNSYPGMITNAMFCAGYLEGGKDSCQGDSG 197 Query: 209 GPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQA 253 GP++CNG LQG+VS+G C + G PGVY +C F +W+ T+ + Sbjct: 198 GPVVCNGELQGVVSWGYG-CAEPGNPGVYAKVCIFNDWLTSTMAS 241 >4WWY-A nrPDB Length = 224 Score = 172 bits (436), Expect = 1e-43, Method: Compositional matrix adjust. Identities = 90/226 (39%), Positives = 132/226 (58%), Gaps = 5/226 (2%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 I+ G +C +S P+Q +L FC G L++ QWV+SA HC+++ + LG H++E Sbjct: 1 IVGGYNCEENSVPYQVSL-NSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEV-L 58 Query: 91 EPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLV 150 E Q + A+ +RHP+Y+R L ND+MLIKL + + +IS+ + P G CL+ Sbjct: 59 EGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINAHVSTISLPTAPPATGTKCLI 118 Query: 151 SGWGLLAN--GRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDSG 208 SGWG A+ P LQC++ V+S+ C Y +MFC G KDSC DSG Sbjct: 119 SGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQRDSG 178 Query: 209 GPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 GP++CNG LQG+VS+G C Q PGVYT + + +WI+ T+ A+ Sbjct: 179 GPVVCNGQLQGVVSWGDG-CAQKNKPGVYTKVYNYVKWIKNTIAAN 223 >1SGF-A nrPDB Length = 240 Score = 169 bits (428), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 89/229 (38%), Positives = 131/229 (57%), Gaps = 15/229 (6%) Query: 36 DCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQEPGSQ 95 DC +SQPW A+ N+ C GVL+ WVL+AAHC+ + Y + LG ++ D EP Q Sbjct: 10 DCE-NSQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHCYNDKYQVWLGKNNFLED-EPSDQ 67 Query: 96 MVEASLSVRHPEYNRPLL-----------ANDLMLIKLDESVSESDTIRSISIASQCPTA 144 S ++ HP++N LL +NDLML++L + +D ++ I++ ++ P Sbjct: 68 HRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEEPKL 127 Query: 145 GNSCLVSGWGLLA--NGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDS 202 G++CL SGWG + P LQCVN+ ++ E C K ++ +M CAG + Sbjct: 128 GSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAMLCAGEMDGGSYT 187 Query: 203 CNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 251 C DSGGPLIC+G LQG+ S+G PCG+ P VYT L KF+ WI +T+ Sbjct: 188 CEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRETM 236 >5C67-A nrPDB Length = 224 Score = 168 bits (425), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 89/226 (39%), Positives = 129/226 (57%), Gaps = 5/226 (2%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 I+ G C +S P+Q +L FC G L+ QWV+SAAHC++ + LG H+++ Sbjct: 1 IVGGYTCEENSLPYQVSL-NSGSHFCGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKV-L 58 Query: 91 EPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLV 150 E Q + A+ +RHP+YNR L ND+MLIKL + + +IS+ + P AG CL+ Sbjct: 59 EGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPPAAGTECLI 118 Query: 151 SGWG--LLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDSG 208 SGWG L P L+C++ V+++ C Y SMFC G KDSC D+G Sbjct: 119 SGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSCQRDAG 178 Query: 209 GPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 GP++CNG LQG+VS+G C PGVYT + + +WI+ T+ A+ Sbjct: 179 GPVVCNGQLQGVVSWGHG-CAWKNRPGVYTKVYNYVDWIKDTIAAN 223 >1F7Z-A nrPDB Length = 233 Score = 167 bits (424), Expect = 3e-42, Method: Compositional matrix adjust. Identities = 89/226 (39%), Positives = 134/226 (59%), Gaps = 5/226 (2%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 I+ G C +S P+Q +L FC G L++ QWV+SAAHC+++ + LG H++ Sbjct: 11 IVGGYTCQENSVPYQVSL-NSGYHFCGGSLINDQWVVSAAHCYKSRIQVRLGEHNINV-L 68 Query: 91 EPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLV 150 E Q V A+ ++HP ++R L ND+MLIKL V + + ++++ S C AG CL+ Sbjct: 69 EGNEQFVNAAKIIKHPNFDRKTLNNDIMLIKLSSPVKLNARVATVALPSSCAPAGTQCLI 128 Query: 151 SGWG-LLANG-RMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDSG 208 SGWG L++G P +LQC++ ++ + C Y +M C G KDSC GDSG Sbjct: 129 SGWGNTLSSGVNEPDLLQCLDAPLLPQADCEASYPGKITDNMVCVGFLEGGKDSCQGDSG 188 Query: 209 GPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 GP++CNG LQG+VS+G C PGVYT +C + +WI+ T+ A+ Sbjct: 189 GPVVCNGELQGIVSWGYG-CALPDNPGVYTKVCNYVDWIQDTIAAN 233 >2TLD-E nrPDB Length = 220 Score = 167 bits (423), Expect = 4e-42, Method: Compositional matrix adjust. Identities = 89/226 (39%), Positives = 134/226 (59%), Gaps = 8/226 (3%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 I+ G C ++ P+Q +L FC G L++ QWV+SAAHC+++ + LG ++ Sbjct: 1 IVGGYTCGANTVPYQVSL-NSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINV-V 58 Query: 91 EPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLV 150 E Q + AS S+ HP YN L ND+MLIKL + S + + SIS+ + C +AG CL+ Sbjct: 59 EGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLI 118 Query: 151 SGWGLLANG--RMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDSG 208 SGWG + P VL+C+ ++S+ C Y +MFCA G + DSC GDSG Sbjct: 119 SGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCA--GLEGGDSCQGDSG 176 Query: 209 GPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 GP++C+G LQG+VS+G C + PGVYT +C + WI++T+ ++ Sbjct: 177 GPVVCSGKLQGIVSWGSG-CAK-NKPGVYTKVCNYVSWIKQTIASN 220 >1GVZ-A nrPDB Length = 237 Score = 164 bits (414), Expect = 4e-41, Method: Compositional matrix adjust. Identities = 86/237 (36%), Positives = 130/237 (54%), Gaps = 14/237 (5%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 II G +C HS+PWQ A+ + C GVLVHPQWVL+AAHC + Y I LG H+L D Sbjct: 1 IIGGWECEKHSKPWQVAVYHQGHFQCGGVLVHPQWVLTAAHCMSDDYQIWLGRHNLSKD- 59 Query: 91 EPGSQMVEASLSVRHPEYNRPLL-----------ANDLMLIKLDESVSESDTIRSISIAS 139 E +Q + S S P+++ LL ++DLML++L + +D ++ + + + Sbjct: 60 EDTAQFHQVSDSFLDPQFDLSLLKKKYLRPYDDISHDLMLLRLAQPARITDAVKILDLPT 119 Query: 140 QCPTAGNSCLVSGWGLLA--NGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGH 197 Q P G++C SGWGL++ R LQCV + + S E C++ Y + CA Sbjct: 120 QEPKLGSTCYTSGWGLISTFTNRGSGTLQCVELRLQSNEKCARAYPEKMTEFVLCATHRD 179 Query: 198 DQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 D C GDSGG LIC+G QG+ S+G + C V+T + +WI++T++ + Sbjct: 180 DSGSICLGDSGGALICDGVFQGITSWGYSECADFNDNFVFTKVMPHKKWIKETIEKN 236 >2EEK-A nrPDB Length = 220 Score = 158 bits (399), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 83/222 (37%), Positives = 129/222 (58%), Gaps = 4/222 (1%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 I+ G +C+ HSQ Q +L FC G LV WV+SAAHC+++ + LG H + + Sbjct: 1 IVGGYECTKHSQAHQVSL-NSGYHFCGGSLVSKDWVVSAAHCYKSVLRVRLGEHHIRVN- 58 Query: 91 EPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLV 150 E Q + +S +RHP Y+ + ND+MLIKL + + + + ++++ ++C C V Sbjct: 59 EGTEQYISSSSVIRHPNYSSYNINNDIMLIKLTKPATLNQYVHAVALPTECAADATMCTV 118 Query: 151 SGWG-LLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDSGG 209 SGWG +++ LQC+++ ++S C+ Y + SMFCAG KDSC GDSGG Sbjct: 119 SGWGNTMSSVADGDKLQCLSLPILSHADCANSYPGMITQSMFCAGYLEGGKDSCQGDSGG 178 Query: 210 PLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 251 P++CNG LQG+VS+G C + PGVY +C + W+ T+ Sbjct: 179 PVVCNGVLQGVVSWGYG-CAERDHPGVYAKVCVLSGWVRDTM 219 >4GSO-A nrPDB Length = 232 Score = 156 bits (395), Expect = 8e-39, Method: Compositional matrix adjust. Identities = 84/224 (37%), Positives = 127/224 (56%), Gaps = 5/224 (2%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 ++ G++C + P+ A + + FC L++ +WV++AAHC ++ + LG+HS + Sbjct: 1 VLGGDECDINEHPF-LAFLYSHGYFCGLTLINQEWVVTAAHCDSTNFQMQLGVHSKKVLN 59 Query: 91 EPGSQMVEASLSVRHPEYN-RPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCL 149 E Q P N +L D+MLIKLD+ +S S I +S+ S P+ G+ C Sbjct: 60 E-DEQTRNPKEKFICPNKNMSEVLDKDIMLIKLDKPISNSKHIAPLSLPSNPPSVGSVCR 118 Query: 150 VSGWG--LLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDS 207 + GWG + N P V C N+++V EVC Y+ L + CAG KD+C GDS Sbjct: 119 IMGWGSITIPNETYPDVPYCANINLVDYEVCQGAYNGLPAKTTLCAGVLEGGKDTCVGDS 178 Query: 208 GGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 251 GGPLICNG QG+VS+G CGQ PG+YTN+ +T+WI++ + Sbjct: 179 GGPLICNGQFQGIVSYGAHSCGQGPKPGIYTNVFDYTDWIQRNI 222 >1OP0-A nrPDB Length = 234 Score = 152 bits (384), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 82/227 (36%), Positives = 124/227 (54%), Gaps = 3/227 (1%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 +I G +C + + A FC G L++P+WV++AAHC + + LG+HS + Sbjct: 1 VIGGNECDINEHRFLVAFFNTTGFFCGGTLINPEWVVTAAHCDSTDFQMQLGVHSKKVLN 60 Query: 91 EPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLV 150 E + + N +L D+MLIKLD+ +S S I +S+ S P+ G+ C + Sbjct: 61 EDEQTRNPKEKFICPNKNNNEVLDKDIMLIKLDKPISNSKHIAPLSLPSSPPSVGSVCRI 120 Query: 151 SGWGLLANGR--MPTVLQCVNVSVVSEEVCSKLY-DPLYHPSMFCAGGGHDQKDSCNGDS 207 GWG + + P V C N++++ VC Y + L CAG KD+C GDS Sbjct: 121 MGWGSITPVKETFPDVPYCANINLLDHAVCQAGYPELLAEYRTLCAGIVQGGKDTCGGDS 180 Query: 208 GGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 GGPLICNG QG+VS+G PCGQ PG+YTN+ +T+WI++ + + Sbjct: 181 GGPLICNGQFQGIVSYGAHPCGQGPKPGIYTNVFDYTDWIQRNIAGN 227 >1FXY-A nrPDB Length = 228 Score = 151 bits (382), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 79/228 (34%), Positives = 123/228 (53%), Gaps = 5/228 (2%) Query: 31 IINGEDCSPHSQPWQAALV-MENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEAD 89 I+ G +C PWQA L+ ENE FC G ++ ++L+AAHC + + + + Sbjct: 1 IVGGYNCKDGEVPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTE 60 Query: 90 QEPGSQMV-EASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSC 148 QE G + V E + ++H + + D+ +++L ++ + S+ + P G C Sbjct: 61 QEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPASLPTAPPATGTKC 120 Query: 149 LVSGWGLLAN--GRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGD 206 L+SGWG A+ P LQC++ V+S+ C Y +MFC G KDSC GD Sbjct: 121 LISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGD 180 Query: 207 SGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 SGGP++CNG LQG+VS+G C Q PGVYT + + +WI+ T+ A+ Sbjct: 181 SGGPVVCNGQLQGVVSWGDG-CAQKNKPGVYTKVYNYVKWIKNTIAAN 227 >5LPF-A nrPDB Length = 234 Score = 147 bits (372), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 85/231 (36%), Positives = 125/231 (54%), Gaps = 13/231 (5%) Query: 34 GEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQEPG 93 G C+ SQPWQ +L C+GVLV WVL+AAHC +G L Q G Sbjct: 7 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQ--G 64 Query: 94 SQMVEASLSVRHPEYNR---PLLA-----NDLMLIKLDESVSESDTIRSISIASQCPTAG 145 Q+ + SV HP+Y++ P+L +DLML+KL V +R++ + +C G Sbjct: 65 EQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPG 124 Query: 146 NSCLVSGWGLLANGRMP--TVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSC 203 + C V+GWG A R+ L C +++++S + C Y + +M CAG Q D C Sbjct: 125 DQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGLDRGQ-DPC 183 Query: 204 NGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 DSGGPL+C+ LQG++S+G PCG P VYT +CK+ WI K ++++ Sbjct: 184 QSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 234 >2AIQ-A nrPDB Length = 231 Score = 147 bits (372), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 78/226 (34%), Positives = 121/226 (53%), Gaps = 4/226 (1%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 +I G++C+ + + ALV N C G L++ +WVL+A HC + + I LG+H+L+ Sbjct: 1 VIGGDECNINEHRF-LALVYANGSLCGGTLINQEWVLTARHCDRGNMRIYLGMHNLKVLN 59 Query: 91 EPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLV 150 + + N + D+MLI+L+ V S I +S+ S P+ G+ C + Sbjct: 60 KDALRRFPKEKYFCLNTRNDTIWDKDIMLIRLNRPVRNSAHIAPLSLPSNPPSVGSVCRI 119 Query: 151 SGWGLLA--NGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDSG 208 GWG + N +P V C N++++ VC Y L + CAG KD+C GDSG Sbjct: 120 MGWGTITSPNATLPDVPHCANINILDYAVCQAAYKGL-AATTLCAGILEGGKDTCKGDSG 178 Query: 209 GPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 GPLICNG QG++S G PC Q PG+YT + +T+WI+ + + Sbjct: 179 GPLICNGQFQGILSVGGNPCAQPRKPGIYTKVFDYTDWIQSIISGN 224 >1EUF-A nrPDB Length = 227 Score = 146 bits (368), Expect = 9e-36, Method: Compositional matrix adjust. Identities = 84/229 (36%), Positives = 123/229 (53%), Gaps = 12/229 (5%) Query: 31 IINGEDCSPHSQPWQAALVME---NELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLE 87 II G + PHS+P+ A L+ + C G LV +VL+AAHC +S + LG H++ Sbjct: 1 IIGGHEAKPHSRPYMAFLLFKTSGKSHICGGFLVREDFVLTAAHCLGSSINVTLGAHNI- 59 Query: 88 ADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTA--G 145 ++E Q++ + HP+YN LAND+ML+KL +D + I++ G Sbjct: 60 MERERTQQVIPVRRPIPHPDYNDETLANDIMLLKLTRKADITDKVSPINLPRSLAEVKPG 119 Query: 146 NSCLVSGWGLLANGRMPTV--LQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSC 203 C V+GWG L MP+ LQ V++ V SEE C + + CAG +K+S Sbjct: 120 MMCSVAGWGRLGVN-MPSTDKLQEVDLEVQSEEKCIARFKNYIPFTQICAGDPSKRKNSF 178 Query: 204 NGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 252 +GDSGGPL+CNG QG+VS+G+ P VYT + F WI T++ Sbjct: 179 SGDSGGPLVCNGVAQGIVSYGR---NDGTTPDVYTRISSFLSWIHSTMR 224 >2ZKS-A nrPDB Length = 240 Score = 146 bits (368), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 87/235 (37%), Positives = 124/235 (52%), Gaps = 15/235 (6%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYT---IGLGLHSLE 87 II G + PHS+P+ A+L C GVLVHP+WVL+AAHC + LGLH+L+ Sbjct: 1 IIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTAAHCLAQRMAQLRLVLGLHTLD 60 Query: 88 ADQEPGSQMVEASLSVRHPEYNR-PLLANDLMLIKLDESVSESDTIRSISIAS--QCPTA 144 + PG +++HP Y P L NDL L++LD V S TIR +++ S Q A Sbjct: 61 S---PGLTF-HIKAAIQHPRYKPVPALENDLALLQLDGKVKPSRTIRPLALPSKRQVVAA 116 Query: 145 GNSCLVSGWGLLAN-GRMPTVLQCVNVSVVSEEVC--SKLYDPLYHPSMFCAGGGHDQKD 201 G C ++GWGL GR+ VL+ +++ V+ +C S+ ++ PSM C + Sbjct: 117 GTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRFWNGSLSPSMVCLAADSKDQA 176 Query: 202 SCNGDSGGPLICNG--YLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 C GDSGGPL+C L G++SF C + P V T + + WI K S Sbjct: 177 PCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVATAVAPYVSWIRKVTGRS 231 >4E7N-A nrPDB Length = 238 Score = 144 bits (364), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 84/228 (36%), Positives = 118/228 (51%), Gaps = 7/228 (3%) Query: 31 IINGEDCSPHSQPWQAALVMENE--LFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEA 88 II G++C+ + + AL LFC G L++ +WVL+AAHC + ++ I LG+HS + Sbjct: 1 IIGGDECNINEHRFLVALYTSRSRTLFCGGTLINQEWVLTAAHCDRKNFRIKLGMHSKKV 60 Query: 89 DQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSC 148 E V N L D+MLI+LD V S I S+ S P+ G+ C Sbjct: 61 PNEDEQTRVPKEKFFCLSSKNYTLWDKDIMLIRLDSPVKNSKHIAPFSLPSSPPSVGSVC 120 Query: 149 LVSGWGLLA--NGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSM---FCAGGGHDQKDSC 203 + GWG ++ G P V CVN++++ E+C Y P+ CAG KD+C Sbjct: 121 RIMGWGRISPTEGTYPDVPHCVNINLLEYEMCRAPYPEFELPATSRTLCAGILEGGKDTC 180 Query: 204 NGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 251 GDSGGPLICNG QG+ S+G PC Q P YT + +WIE + Sbjct: 181 KGDSGGPLICNGQFQGIASWGDDPCAQPHKPAAYTKVFDHLDWIENII 228 >3S69-A nrPDB Length = 234 Score = 144 bits (364), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 83/224 (37%), Positives = 122/224 (54%), Gaps = 3/224 (1%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 +I G++C+ + A FCSG L++ +WVL+AAHC ++ + LG+HS + Sbjct: 1 VIGGDECNINEHRSLVAFFNSTGFFCSGTLINEEWVLTAAHCDNTNFQMKLGVHSKKVLN 60 Query: 91 EPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLV 150 E + + N +L D+MLIKLD VS S+ I +S+ S P+ G+ C + Sbjct: 61 EDEQTRNPKEKFICPNKKNDEVLDKDIMLIKLDSRVSNSEHIVPLSLPSSPPSVGSVCHI 120 Query: 151 SGWGLLANGRM--PTVLQCVNVSVVSEEVCSKLY-DPLYHPSMFCAGGGHDQKDSCNGDS 207 GWG + ++ P V C ++++ + VC Y + L CAG KD+C GDS Sbjct: 121 MGWGSITPIKVTYPDVPYCAYINLLDDAVCQAGYPELLTEYRTLCAGILEGGKDTCGGDS 180 Query: 208 GGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 251 GGPLICNG QG+VSFG PCGQ PGVYT + + WI+ + Sbjct: 181 GGPLICNGQFQGIVSFGAHPCGQGLKPGVYTKVFDYNHWIQSII 224 >3G01-A nrPDB Length = 227 Score = 142 bits (357), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 77/230 (33%), Positives = 127/230 (55%), Gaps = 12/230 (5%) Query: 31 IINGEDCSPHSQPWQAAL----VMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSL 86 II G + SPHS+P+ A V ++FC G LV ++VL+AAHC S T+ LG H++ Sbjct: 1 IIGGNEISPHSRPYMAYYEFLKVGGKKMFCGGFLVRDKFVLTAAHCKGRSMTVTLGAHNI 60 Query: 87 EADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCP--TA 144 +A +E Q++ + ++ HP+YN +ND+ML+KL + + +R +++ + Sbjct: 61 KAKEET-QQIIPVAKAIPHPDYNPDDRSNDIMLLKLVRNAKRTRAVRPLNLPRRNAHVKP 119 Query: 145 GNSCLVSGWGLLA-NGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPS-MFCAGGGHDQKDS 202 G+ C V+GWG + +G P L V ++V ++VC + Y+ + C G + S Sbjct: 120 GDECYVAGWGKVTPDGEFPKTLHEVKLTVQKDQVCESQFQSSYNRANEICVGDSKIKGAS 179 Query: 203 CNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 252 GDSGGPL+C G+VS+G+ P V+T + F WI+KT++ Sbjct: 180 FRGDSGGPLVCKRAAAGIVSYGQT---DGSAPQVFTRVLSFVSWIKKTMK 226 >1MZD-A nrPDB Length = 240 Score = 141 bits (356), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 89/233 (38%), Positives = 124/233 (53%), Gaps = 17/233 (7%) Query: 30 QIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIG------LGL 83 +II G++ SPHS+P+ A++ C GVL+ PQWVL+AAHC Q +T G LG Sbjct: 2 EIIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHC-QYRFTKGQSPTVVLGA 60 Query: 84 HSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCP- 142 HSL + E Q +E + +ND+ML+KL + + ++ + I S+ Sbjct: 61 HSLSKN-EASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHIRSKTSL 119 Query: 143 TAGNSCLVSGWGLLANG--RMPTVLQCVNVSVVSEEVC-SKLY---DPLYHPSMFCAGGG 196 +G C V+GWG R L+ V V+V+S ++C S+ Y DP M CAG Sbjct: 120 RSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAGDA 179 Query: 197 HDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLC-KFTEWIE 248 QKDSC GD+GGPLIC G +VS G CG PG+YT L K+ WI+ Sbjct: 180 KGQKDSCKGDAGGPLICKGVFHAIVSGGHE-CGVATKPGIYTLLTKKYQTWIK 231 >3S9B-A nrPDB Length = 234 Score = 140 bits (354), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 78/228 (34%), Positives = 121/228 (53%), Gaps = 11/228 (4%) Query: 31 IINGEDCSPHSQPWQAALVME--NELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEA 88 ++ G++C+ + P+ AL + + C+G L++ +WVL+AAHC + + I LG+HS Sbjct: 1 VVGGDECNINEHPFLVALYTSASSTIHCAGALINREWVLTAAHCDRRNIRIKLGMHSKNI 60 Query: 89 DQEPGSQMVEAS----LSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTA 144 E V L+ + P L D+MLI+L V+ S I +S+ S+ Sbjct: 61 RNEDEQIRVPRGKYFCLNTKFPNG----LDKDIMLIRLRRPVTYSTHIAPVSLPSRSRGV 116 Query: 145 GNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSM-FCAGGGHDQKDSC 203 G+ C + GWG ++ P V C N+ +V + C LY + S CAG +D+C Sbjct: 117 GSRCRIMGWGKISTTTYPDVPHCTNIFIVKHKWCEPLYPWVPADSRTLCAGILKGGRDTC 176 Query: 204 NGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 251 +GDSGGPLICNG + G+V+ G PCGQ P VYT + + WI+ + Sbjct: 177 HGDSGGPLICNGEMHGIVAGGSEPCGQHLKPAVYTKVFDYNNWIQSII 224 >1FDP-A nrPDB Length = 235 Score = 138 bits (348), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 76/231 (32%), Positives = 126/231 (54%), Gaps = 12/231 (5%) Query: 30 QIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNS----YTIGLGLHS 85 +I+ G + H++P+ A++ + C GVLV QWVLSAAHC +++ + LG HS Sbjct: 7 RILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQVLLGAHS 66 Query: 86 LEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSI--SIASQCPT 143 L + EP ++ + +V HP+ + +DL+L++L E + +R + + Sbjct: 67 L-SQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVA 125 Query: 144 AGNSCLVSGWGLLAN-GRMPTVLQCVNVSVVSEEVCSKL--YDPLYHPSMFCAGGGHDQK 200 G C V+GWG++ + GR P LQ V + V+ C++ +D + CA +++ Sbjct: 126 PGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITERLMCAES--NRR 183 Query: 201 DSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 251 DSC GDSGGPL+C G L+G+V+ G CG PG+YT + + WI+ + Sbjct: 184 DSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVL 234 >1NN6-A nrPDB Length = 228 Score = 138 bits (347), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 84/234 (35%), Positives = 123/234 (52%), Gaps = 16/234 (6%) Query: 30 QIINGEDCSPHSQPWQAAL--VMEN--ELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHS 85 +II G +C PHS+P+ A L V N FC G L+ +VL+AAHC S T+ LG H+ Sbjct: 2 EIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHN 61 Query: 86 LEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTA- 144 + ++E Q +E RHP+YN L +D+ML+KL E S + + ++ SQ Sbjct: 62 I-TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVP 120 Query: 145 -GNSCLVSGWG---LLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQK 200 G C V+GWG +L G LQ V + ++ + CS D H C G K Sbjct: 121 PGRMCRVAGWGRTGVLKPGS--DTLQEVKLRLMDPQACSHFRD-FDHNLQLCVGNPRKTK 177 Query: 201 DSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 + GDSGGPL+C G QG+VS+G++ P V+T + + WI + +QA+ Sbjct: 178 SAFKGDSGGPLLCAGVAQGIVSYGRS---DAKPPAVFTRISHYRPWINQILQAN 228 >1BQY-A nrPDB Length = 234 Score = 134 bits (338), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 79/228 (34%), Positives = 120/228 (52%), Gaps = 5/228 (2%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 + G++C+ + L N C G L++ WV++AAHC N++ + G+HS + Sbjct: 1 VFGGDECNINEHRSLVVLFNSNGFLCGGTLINQDWVVTAAHCDSNNFQLLFGVHSKKILN 60 Query: 91 EPGSQMVEASLSVRHPEYNRP-LLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCL 149 E Q + P + + D+MLIKLD SVS S+ I +S+ S P+ G+ C Sbjct: 61 E-DEQTRDPKEKFFCPNRKKDDEVDKDIMLIKLDSSVSNSEHIAPLSLPSSPPSVGSVCR 119 Query: 150 VSGWGLLANGR--MPTVLQCVNVSVVSEEVCSKLYD-PLYHPSMFCAGGGHDQKDSCNGD 206 + GWG + P V C N++++ VC Y + CAG +D+C+ D Sbjct: 120 IMGWGKTIPTKEIYPDVPHCANINILDHAVCRTAYSWRQVANTTLCAGILQGGRDTCHFD 179 Query: 207 SGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 SGGPLICNG QG+VS+G PCGQ G PGVYT + + +WI+ + + Sbjct: 180 SGGPLICNGIFQGIVSWGGHPCGQPGEPGVYTKVFDYLDWIKSIIAGN 227 >5XRF-A nrPDB Length = 242 Score = 134 bits (337), Expect = 4e-32, Method: Compositional matrix adjust. Identities = 78/228 (34%), Positives = 124/228 (54%), Gaps = 9/228 (3%) Query: 31 IINGEDCSPHSQPWQAALVMEN--ELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLH--SL 86 +I G +C + + AA C+G L+H +WVL+AAHC++ I LG+H S+ Sbjct: 7 VIGGNECDTNEHRFLAAFFTSRPWTFQCAGTLIHEEWVLAAAHCYKRGLNIYLGMHNQSI 66 Query: 87 EADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGN 146 + D E +E + + D++L+KL++ VS S I +S+ S P+ G+ Sbjct: 67 QFDDEQRRYAIEEHYYRCDEKLTK--WEKDVVLLKLNKPVSNSTHIAPLSLPSSPPSIGS 124 Query: 147 SCLVSGWGLLANGR--MPTVLQCVNVSVVSEEVCSKLY-DPLYHPSMFCAGGGHDQKDSC 203 C V GWG++++ + +P V C N+++++ C Y D + CAG D+C Sbjct: 125 VCRVMGWGIMSSTKDILPDVPHCANINLLNYMECVAHYPDVPETTRLLCAGVLEGGIDTC 184 Query: 204 NGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 251 N DSGGPLIC+G QG+V FGK PC Q PG+YT + + +WI+ + Sbjct: 185 NQDSGGPLICDGQFQGIVFFGKYPCAQPNKPGLYTRVSNYNDWIQNII 232 >1KYN-A nrPDB Length = 235 Score = 133 bits (335), Expect = 6e-32, Method: Compositional matrix adjust. Identities = 74/229 (32%), Positives = 127/229 (55%), Gaps = 11/229 (4%) Query: 31 IINGEDCSPHSQPWQAALVMEN---ELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLE 87 II G + PHS+P+ A L +++ + C G LV +VL+AAHC+ ++ + LG H+++ Sbjct: 1 IIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQ 60 Query: 88 ADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISI--ASQCPTAG 145 +E Q + A ++RHP+YN+ + ND+ML++L V + + +++ A + G Sbjct: 61 R-RENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPG 119 Query: 146 NSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNG 205 C V+GWG ++ R L+ V + V + C +++ C G ++K + G Sbjct: 120 TLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKAAFKG 179 Query: 206 DSGGPLICNGYLQGLVSFGKAPCGQVGV-PGVYTNLCKFTEWIEKTVQA 253 DSGGPL+CN G+VS+GK+ GV P V+T + F WI T+++ Sbjct: 180 DSGGPLLCNNVAHGIVSYGKSS----GVPPEVFTRVSSFLPWIRTTMRS 224 >1IAU-A nrPDB Length = 227 Score = 132 bits (331), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 75/229 (32%), Positives = 121/229 (52%), Gaps = 11/229 (4%) Query: 31 IINGEDCSPHSQPWQAALVMENEL---FCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLE 87 II G + PHS+P+ A L++ ++ C G L+ +VL+AAHC+ +S + LG H+++ Sbjct: 1 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 60 Query: 88 ADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCP--TAG 145 +QEP Q + + HP YN +ND+ML++L+ + ++ + + S G Sbjct: 61 -EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPG 119 Query: 146 NSCLVSGWGLLAN-GRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSM-FCAGGGHDQKDSC 203 +C V+GWG A G+ LQ V ++V + C Y ++ C G +K S Sbjct: 120 QTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSF 179 Query: 204 NGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 252 GDSGGPL+CN QG+VS+G+ P T + F WI+KT++ Sbjct: 180 KGDSGGPLVCNKVAQGIVSYGR---NNGMPPRACTKVSSFVHWIKKTMK 225 >5FCR-A nrPDB Length = 234 Score = 131 bits (329), Expect = 4e-31, Method: Compositional matrix adjust. Identities = 77/229 (33%), Positives = 124/229 (54%), Gaps = 13/229 (5%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQ-----NSYTIGLGLHS 85 I+ G++ + H++P+ A++ + C G L+ QWVLSAAHC +S + LG HS Sbjct: 1 ILGGQEAAAHARPYMASVQVNGTHVCGGTLLDEQWVLSAAHCMDGVTDDDSVQVLLGAHS 60 Query: 86 LEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTA- 144 L A EP + + V HP L +DL+L KL ++ S +R + + + Sbjct: 61 LSA-PEPYKRWYDVQSVVPHPGSRPDSLEDDLILFKLSQNASLGPHVRPLPLQYEDKEVE 119 Query: 145 -GNSCLVSGWGLLAN-GRMPTVLQCVNVSVVSEEVCS--KLYDPLYHPSMFCAGGGHDQK 200 G C V+GWG++ + GR P VL + VS+++ C+ +D + +M CA +++ Sbjct: 120 PGTLCDVAGWGVVTHAGRRPDVLHQLRVSIMNRTTCNLRTYHDGVVTINMMCAES--NRR 177 Query: 201 DSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEK 249 D+C GDSG PL+C ++G+V++G CG PGVYT + + WIE Sbjct: 178 DTCRGDSGSPLVCGDAVEGVVTWGSRVCGNGKKPGVYTRVSSYRMWIEN 226 >1FI8-A nrPDB Length = 228 Score = 130 bits (327), Expect = 5e-31, Method: Compositional matrix adjust. Identities = 75/232 (32%), Positives = 122/232 (52%), Gaps = 12/232 (5%) Query: 31 IINGEDCSPHSQPWQAALVMENEL----FCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSL 86 II G + PHS+P+ A L + +E C G L+ +VL+AAHC + + LG H++ Sbjct: 1 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKIQVTLGAHNI 60 Query: 87 EADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTA-- 144 + +QE Q++ + HP YN ++ND+ML+KL S ++ +++ + Sbjct: 61 K-EQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKP 119 Query: 145 GNSCLVSGWGLLA-NGRMPTVLQCVNVSVVSEEVC-SKLYDPLYHPSMFCAGGGHDQKDS 202 G+ C V+GWG L G+ LQ V ++V ++ C S L + + CAG ++ S Sbjct: 120 GDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRAS 179 Query: 203 CNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 GDSGGPL+C G+VS+G+ P +T + F WI+KT++ S Sbjct: 180 FRGDSGGPLVCKKVAAGIVSYGQ---NDGSTPRAFTKVSTFLSWIKKTMKKS 228 >4Q7Y-A nrPDB Length = 250 Score = 130 bits (326), Expect = 7e-31, Method: Compositional matrix adjust. Identities = 78/233 (33%), Positives = 117/233 (50%), Gaps = 10/233 (4%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQN----SYTIGLGLHSL 86 II G + +PHS+P+ A++ + C G L+ +WV+SAAHCF + + + LG H L Sbjct: 1 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 60 Query: 87 EADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTI---RSISIASQCPT 143 + EP Q+ HP+Y+ AND+ L++L+ S + R ++ PT Sbjct: 61 -STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRLPGRRARPPT 119 Query: 144 AGNSCLVSGWGLLAN-GRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDS 202 AG C V+GWG +++ +P L V V+ +VC+ + +M C G + Sbjct: 120 AGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRG 179 Query: 203 -CNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 C+ DSGGPL+C GLVSF CG P VYT + F WI V+ S Sbjct: 180 FCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRS 232 >1ORF-A nrPDB Length = 234 Score = 128 bits (322), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 78/234 (33%), Positives = 122/234 (52%), Gaps = 11/234 (4%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYT-IGLGLHSLEAD 89 II G + +PHS+P+ L ++ + C+G L+ WVL+AAHC N + + LG HS+ Sbjct: 1 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSI-TR 59 Query: 90 QEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDES--VSESDTIRSISIASQCPTAGNS 147 +EP Q++ +P Y+ DL L++L E +++ TI + G Sbjct: 60 EEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLTEKAKINKYVTILHLPKKGDDVKPGTM 119 Query: 148 CLVSGWGLLAN-GRMPTVLQCVNVSVVSEEVCSKL----YDPLYHPSMFCAGGGHDQKDS 202 C V+GWG N L+ V ++++ +VC+ ++P+ +M CAG +DS Sbjct: 120 CQVAGWGRTHNSASWSDTLREVEITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDS 179 Query: 203 CNGDSGGPLICNGYLQGLVSFG-KAPCGQVGVPGVYTNLC-KFTEWIEKTVQAS 254 CNGDSG PL+C G +G+ SFG + CG PGVY L K WI T++ + Sbjct: 180 CNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKGA 233 >1BRU-P nrPDB Length = 241 Score = 128 bits (322), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 91/240 (37%), Positives = 125/240 (52%), Gaps = 21/240 (8%) Query: 31 IINGEDCSPHSQPWQAALVMEN----ELFCSGVLVHPQWVLSAAHCFQNS--YTIGLGLH 84 ++ GED P+S PWQ +L ++ C G LV WVL+AAHC +S Y + LG H Sbjct: 1 VVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISSSRTYRVVLGRH 60 Query: 85 SLEADQEPGSQMVEASLSVRHPEYNRPLLA--NDLMLIKLDESVSESDTIRSISIASQCP 142 SL + EPGS V+ S V H ++N L+ ND+ L+KL VS +D I+ + + Sbjct: 61 SLSTN-EPGSLAVKVSKLVVHQDWNSNQLSNGNDIALLKLASPVSLTDKIQLGCLPAAGT 119 Query: 143 TAGNS--CLVSGWGLL-ANGRMPTVLQCVNVSVVSEEVCSK--LYDPLYHPSMFCAGGGH 197 N+ C V+GWG L NG P +LQ + VV CSK + +M CA GG Sbjct: 120 ILPNNYVCYVTGWGRLQTNGASPDILQQGQLLVVDYATCSKPGWWGSTVKTNMICA-GGD 178 Query: 198 DQKDSCNGDSGGPLICNG-----YLQGLVSFGKA-PCGQVGVPGVYTNLCKFTEWIEKTV 251 SCNGDSGGPL C G + G+VSFG + C P V+T + + +WI + Sbjct: 179 GIISSCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRVSNYIDWINSVI 238 >1PYT-D nrPDB Length = 251 Score = 127 bits (320), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 87/240 (36%), Positives = 124/240 (51%), Gaps = 17/240 (7%) Query: 29 SQIINGEDCSPHSQPWQAAL--VMEN--ELFCSGVLVHPQWVLSAAHCFQNS--YTIGLG 82 ++++ GED PHS PWQ +L + +N C G L+ P VL+AAHC N+ Y + LG Sbjct: 12 ARVVGGEDAIPHSWPWQISLQYLRDNTWRHTCGGTLITPNHVLTAAHCISNTLTYRVALG 71 Query: 83 LHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCP 142 ++LE + E GS V H ++N L+ ND+ LIKL E+V DTI+ + S+ Sbjct: 72 KNNLEVEDEAGSLYVGVDTIFVHEKWNSFLVRNDIALIKLAETVELGDTIQVACLPSEGS 131 Query: 143 TAGNS--CLVSGWG-LLANGRMPTVLQCVNVSVVSEEVCSKL--YDPLYHPSMFCAGGGH 197 C V+GWG L NG + LQ VV CS+ + +M CA GG Sbjct: 132 LLPQDYPCFVTGWGRLYTNGPIAAELQQGLQPVVDYATCSQRDWWGTTVKETMVCA-GGD 190 Query: 198 DQKDSCNGDSGGPLICNG----YLQGLVSFGKA-PCGQVGVPGVYTNLCKFTEWIEKTVQ 252 +CNGDSGGPL C ++G+VSFG C P V+T + + +WI + +Q Sbjct: 191 GVISACNGDSGGPLNCQADGQWDVRGIVSFGSGLSCNTFKKPTVFTRVSAYIDWINQKLQ 250 >3TK9-A nrPDB Length = 226 Score = 127 bits (319), Expect = 4e-30, Method: Compositional matrix adjust. Identities = 72/228 (31%), Positives = 119/228 (52%), Gaps = 10/228 (4%) Query: 31 IINGEDCSPHSQPWQAA---LVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLE 87 II G + PHS+P+ A L ++ C G+LV +VL+AAHC +S + LG H+++ Sbjct: 1 IIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAHCQGSSINVTLGAHNIK 60 Query: 88 ADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTA--G 145 +QE Q + + HP YN +N++ML++L+ + +R + + S G Sbjct: 61 -EQERTQQFIPVKRPIPHPAYNPKNFSNNIMLLQLERKAKWTTAVRPLRLPSSKAQVKPG 119 Query: 146 NSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYDPLY-HPSMFCAGGGHDQKDSCN 204 C V+GWG ++ + T LQ V ++V + C +L+ Y + C G + Sbjct: 120 QLCSVAGWGYVSMSTLATTLQEVLLTVQKDCQCERLFHGNYSRATEICVGDPKKTQTGFK 179 Query: 205 GDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 252 GDSGGPL+C QG++S+G + PGVY + F WI++T++ Sbjct: 180 GDSGGPLVCKDVAQGILSYGNK---KGTPPGVYIKVSHFLPWIKRTMK 224 >4H4F-A nrPDB Length = 249 Score = 127 bits (319), Expect = 4e-30, Method: Compositional matrix adjust. Identities = 89/239 (37%), Positives = 125/239 (52%), Gaps = 18/239 (7%) Query: 31 IINGEDCSPHSQPWQAAL-VMENELF---CSGVLVHPQWVLSAAHCFQNS--YTIGLGLH 84 ++ GED PHS PWQ +L ++N+ + C G L+ +VL+AAHC N+ Y + +G + Sbjct: 1 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 60 Query: 85 SLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTA 144 +LE + E GS V H +N LL ND+ LIKL E V SDTI+ + + Sbjct: 61 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 120 Query: 145 GNS--CLVSGWG-LLANGRMPTVLQCVNVSVVSEEVCSKL--YDPLYHPSMFCAGGGHDQ 199 C V+GWG L NG + LQ VV CS++ + +M CA GG Sbjct: 121 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCA-GGDGV 179 Query: 200 KDSCNGDSGGPLIC---NGYLQ--GLVSFG-KAPCGQVGVPGVYTNLCKFTEWIEKTVQ 252 +CNGDSGGPL C NG + G+VSFG + C P VYT + + +WI + +Q Sbjct: 180 ISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 238 >2CGA-A nrPDB Length = 245 Score = 126 bits (317), Expect = 8e-30, Method: Compositional matrix adjust. Identities = 77/235 (32%), Positives = 123/235 (52%), Gaps = 12/235 (5%) Query: 29 SQIINGEDCSPHSQPWQAALVMENEL-FCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLE 87 S+I+NGE+ P S PWQ +L + FC G L++ WV++AAHC + + + + Sbjct: 14 SRIVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGVTTSDVVVAGEFDQ 73 Query: 88 ADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISI--ASQCPTAG 145 Q ++ + ++ +YN + ND+ L+KL + S S T+ ++ + AS AG Sbjct: 74 GSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDDFAAG 133 Query: 146 NSCLVSGWGL--LANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSC 203 +C+ +GWGL N P LQ ++ ++S C K + +M CAG SC Sbjct: 134 TTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKKYWGTKIKDAMICAGASG--VSSC 191 Query: 204 NGDSGGPLIC--NG--YLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 GDSGGPL+C NG L G+VS+G + C PGVY + W+++T+ A+ Sbjct: 192 MGDSGGPLVCKKNGAWTLVGIVSWGSSTC-STSTPGVYARVTALVNWVQQTLAAN 245 >3DFJ-A nrPDB Length = 263 Score = 125 bits (314), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 84/231 (36%), Positives = 114/231 (49%), Gaps = 24/231 (10%) Query: 43 PWQAALVMENELFCSGVLVHPQWVLSAAHCF-----QNSYTIGLGLHSLEADQEPGSQMV 97 PWQ ++ E C G LV QWVLSAAHCF + +Y + LG H L++ E Sbjct: 13 PWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAKVST 72 Query: 98 EASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNS--CLVSGWGL 155 + + HP Y + D+ L++L ++ S IR IS+ + + N C V+GWG Sbjct: 73 LKDI-IPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAANASFPNGLHCTVTGWGH 131 Query: 156 LANG---RMPTVLQCVNVSVVSEEVCSKLYDPLYHP--------SMFCAGGGHDQKDSCN 204 +A P LQ + V ++S E C+ LY+ P M CAG KD+C Sbjct: 132 VAPSVSLLTPKPLQQLEVPLISRETCNALYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQ 191 Query: 205 GDSGGPLICN----GYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 251 GDSGGPL C YL G+VS+G A CG PGVYT + WI+ V Sbjct: 192 GDSGGPLSCPVEGLWYLTGIVSWGDA-CGARNRPGVYTLASSYASWIQSKV 241 >3E0N-B nrPDB Length = 271 Score = 125 bits (313), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 84/231 (36%), Positives = 114/231 (49%), Gaps = 24/231 (10%) Query: 43 PWQAALVMENELFCSGVLVHPQWVLSAAHCF-----QNSYTIGLGLHSLEADQEPGSQMV 97 PWQ ++ E C G LV QWVLSAAHCF + +Y + LG H L++ E Sbjct: 13 PWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAKVST 72 Query: 98 EASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGN--SCLVSGWGL 155 + + HP Y + D+ L++L ++ S IR IS+ + + N C V+GWG Sbjct: 73 LKDI-IPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAAQASFPNGLHCTVTGWGH 131 Query: 156 LANG---RMPTVLQCVNVSVVSEEVCSKLYDPLYHP--------SMFCAGGGHDQKDSCN 204 +A P LQ + V ++S E C+ LY+ P M CAG KD+C Sbjct: 132 VAPSVSLLTPKPLQQLEVPLISRETCNSLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQ 191 Query: 205 GDSGGPLICN----GYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 251 GDSGGPL C YL G+VS+G A CG PGVYT + WI+ V Sbjct: 192 GDSGGPLSCPVEGLWYLTGIVSWGDA-CGARNRPGVYTLASSYASWIQSKV 241 >1AZZ-A nrPDB Length = 226 Score = 124 bits (311), Expect = 4e-29, Method: Compositional matrix adjust. Identities = 71/223 (31%), Positives = 118/223 (52%), Gaps = 7/223 (3%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNS--YTIGLGLHSLEA 88 I+ G + P+S P QAAL +++ FC G L+ P+W+L+AAHC + + LG H++ Sbjct: 1 IVGGVEAVPNSWPHQAALFIDDMYFCGGSLISPEWILTAAHCMDGAGFVDVVLGAHNIRE 60 Query: 89 DQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSC 148 D+ + +V H YN +++ND+ +I+L V+ + I ++ + S G Sbjct: 61 DEATQVTIQSTDFTV-HENYNSFVISNDIAVIRLPVPVTLTAAIATVGLPSTDVGVGTVV 119 Query: 149 LVSGWGLLANGRM--PTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGD 206 +GWGL ++ + VL+ V+V ++S C +Y + ++ G K +CNGD Sbjct: 120 TPTGWGLPSDSALGISDVLRQVDVPIMSNADCDAVYGIVTDGNICIDSTG--GKGTCNGD 177 Query: 207 SGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEK 249 SGGPL NG G+ SFG A + G P +T + F +WI+ Sbjct: 178 SGGPLNYNGLTYGITSFGAAAGCEAGYPDAFTRVTYFLDWIQT 220 >1X7A-C nrPDB Length = 235 Score = 124 bits (310), Expect = 5e-29, Method: Compositional matrix adjust. Identities = 76/237 (32%), Positives = 125/237 (52%), Gaps = 15/237 (6%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQN--SYTIGLGLHSLEA 88 I+ GE+ P PWQ L + + FC G +++ +WV++AAHC + T+ G ++ E Sbjct: 1 IVGGENAKPGQFPWQVLLNGKIDAFCGGSIINEKWVVTAAHCIEPGVKITVVAGEYNTE- 59 Query: 89 DQEPGSQMVEASLSVRHPEYNRPL--LANDLMLIKLDESVSESDTIRSISIASQCPT--- 143 + EP Q ++ H YN + ++D+ L++LDE ++ + + I IA + T Sbjct: 60 ETEPTEQRRNVIRAIPHHSYNATVNKYSHDIALLELDEPLTLNSYVTPICIADKEYTNIF 119 Query: 144 -AGNSCLVSGWGLLAN-GRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKD 201 S VSGWG + N GR T+LQ + V +V C + + +MFCAG KD Sbjct: 120 LKFGSGYVSGWGRVFNRGRSATILQYLKVPLVDRATCLRSTKFTIYSNMFCAGFHEGGKD 179 Query: 202 SCNGDSGGPLIC----NGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 SC GDSGGP + +L G++S+G+ C G G+YT + ++ WI++ + + Sbjct: 180 SCQGDSGGPHVTEVEGTSFLTGIISWGEE-CAVKGKYGIYTKVSRYVNWIKEKTKLT 235 >5TJX-A nrPDB Length = 263 Score = 122 bits (306), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 85/249 (34%), Positives = 129/249 (51%), Gaps = 22/249 (8%) Query: 24 VSGSCSQIINGEDCSPHSQPWQAALVME---NELFCSGVLVHPQWVLSAAHCF-----QN 75 + + ++I+ G + S PWQ +L ++ C G L+ QWVL+AAHCF Q+ Sbjct: 9 TTKTSTRIVGGTESSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQD 68 Query: 76 SYTIGLGLHSLE--ADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIR 133 + I G+ L P SQ+ E + H Y +D+ LIKL + ++ + Sbjct: 69 VWRIYSGILELSDITKDTPFSQIKEI---IIHQNYKVSEGNHDIALIKLQAPLEYTEFQK 125 Query: 134 SISIASQCPTAG--NSCLVSGWGL-LANGRMPTVLQCVNVSVVSEEVCSKLY-DPLYHPS 189 IS+ S+ T+ +C V+GWG G + +LQ VN+ +V+ E C K Y D Sbjct: 126 PISLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQR 185 Query: 190 MFCAGGGHDQKDSCNGDSGGPLIC--NG--YLQGLVSFGKAPCGQVGVPGVYTNLCKFTE 245 M CAG KD+C GDSGGPL+C NG L G+ S+G+ C + PGVYT + ++ + Sbjct: 186 MVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEG-CARREQPGVYTKVAEYMD 244 Query: 246 WIEKTVQAS 254 WI + Q+S Sbjct: 245 WILEKTQSS 253 >4DGJ-A nrPDB Length = 235 Score = 121 bits (304), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 80/233 (34%), Positives = 117/233 (50%), Gaps = 17/233 (7%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQ------NSYTIGLGLH 84 I+ G D + PW L ++ L C LV W++SAAHC + +T LGLH Sbjct: 1 IVGGSDAKEGAWPWVVGLYYDDRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLH 60 Query: 85 SLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISI--ASQCP 142 P + V +P YNR ND+ ++ L+ V+ +D I+ IS+ +Q Sbjct: 61 MKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPISLPEENQVF 120 Query: 143 TAGNSCLVSGWG-LLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYH--PSMFCAGGGHDQ 199 G +C ++GWG ++ G +LQ +V ++S E C + P Y+ +M CAG Sbjct: 121 PPGRNCSIAGWGTVVYQGTTADILQEADVPLLSNERCQQQM-PEYNITENMICAGYEEGG 179 Query: 200 KDSCNGDSGGPLICNG----YLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIE 248 DSC GDSGGPL+C +L G+ SFG C PGVY + +FTEWI+ Sbjct: 180 IDSCQGDSGGPLMCQENNRWFLAGVTSFGYE-CALPNRPGVYARVSRFTEWIQ 231 >3LC3-A nrPDB Length = 235 Score = 119 bits (299), Expect = 9e-28, Method: Compositional matrix adjust. Identities = 74/237 (31%), Positives = 120/237 (50%), Gaps = 15/237 (6%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQN--SYTIGLGLHSLEA 88 ++ GED P PWQ L + + FC G +V+ +W+++AAHC + T+ G H++E Sbjct: 1 VVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCVETGVKITVVAGEHNIE- 59 Query: 89 DQEPGSQMVEASLSVRHPEYNRPL--LANDLMLIKLDESVSESDTIRSISIASQCPT--- 143 + E Q + H YN + +D+ L++LDE + + + I IA + T Sbjct: 60 ETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEYTNIF 119 Query: 144 -AGNSCLVSGWG-LLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKD 201 S VSGWG + GR VLQ + V +V C + + +MFCAG +D Sbjct: 120 LKFGSGYVSGWGRVFHKGRSALVLQYLRVPLVDRATCLRSTKFTIYNNMFCAGFHEGGRD 179 Query: 202 SCNGDSGGPLIC----NGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 SC GDSGGP + +L G++S+G+ C G G+YT + ++ WI++ + + Sbjct: 180 SCQGDSGGPHVTEVEGTSFLTGIISWGE-ECAMKGKYGIYTKVSRYVNWIKEKTKLT 235 >1KIG-H nrPDB Length = 241 Score = 119 bits (299), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 71/236 (30%), Positives = 118/236 (50%), Gaps = 13/236 (5%) Query: 31 IINGEDCSPHSQPWQAALV-MENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEAD 89 I+ G DC+ PWQA LV ENE FC G +++ +VL+AAHC + + + + Sbjct: 1 IVGGRDCAEGECPWQALLVNEENEGFCGGTILNEFYVLTAAHCLHQAKRFTVRVGDRNTE 60 Query: 90 QEPGSQMV-EASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISI-----ASQCPT 143 QE G++M E ++V+H + + D+ +++L + + + A Sbjct: 61 QEEGNEMAHEVEMTVKHSRFVKETYDFDIAVLRLKTPIRFRRNVAPACLPEKDWAEATLM 120 Query: 144 AGNSCLVSGWGLL-ANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDS 202 + +VSG+G GR+ + L+ + V V C P+MFCAG +D+ Sbjct: 121 TQKTGIVSGFGRTHEKGRLSSTLKMLEVPYVDRSTCKLSSSFTITPNMFCAGYDTQPEDA 180 Query: 203 CNGDSGGPLICNG----YLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 C GDSGGP + ++ G+VS+G+ C + G GVYT + F +WI+K ++A Sbjct: 181 CQGDSGGPHVTRFKDTYFVTGIVSWGEG-CARKGKFGVYTKVSNFLKWIDKIMKAR 235 >2RDL-A nrPDB Length = 226 Score = 119 bits (298), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 72/231 (31%), Positives = 119/231 (51%), Gaps = 12/231 (5%) Query: 31 IINGEDCSPHSQPWQAALVM---ENEL-FCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSL 86 II G +C PH++P+ A L + EN L CSG L+ +V++AAHC S T+ LG H+ Sbjct: 1 IIGGTECRPHARPYMAYLEIVTPENHLSACSGFLIRRNFVMTAAHCAGRSITVLLGAHNK 60 Query: 87 EADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPT--A 144 + +E Q +E HP+Y+ L+ ND+ML+KL E + + + ++ I+++ + Sbjct: 61 KV-KEDTWQKLEVEKQFPHPKYDDRLVLNDIMLLKLKEKANLTLGVGTLPISAKSNSIPP 119 Query: 145 GNSCLVSGWGLLANGRMPT-VLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSC 203 G C GWG P+ LQ V + ++ + C K ++ + C G ++ Sbjct: 120 GRVCRAVGWGRTNVNEPPSDTLQEVKMRILDPQAC-KHFEDFHQEPQLCVGNPKKIRNVY 178 Query: 204 NGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 GDSGGPL+C G QG+ S+ P V+T + + WI K ++ + Sbjct: 179 KGDSGGPLLCAGIAQGIASYV---LRNAKPPSVFTRISHYRPWINKILREN 226 >4MPW-A nrPDB Length = 245 Score = 118 bits (296), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 79/244 (32%), Positives = 122/244 (50%), Gaps = 26/244 (10%) Query: 31 IINGEDCSPHSQPWQAALVMENEL---FCSGVLVHPQWVLSAAHCFQNSYT--IGLGLHS 85 I+ G++ PWQ +L + FC G L+HPQWVL+AAHC L + Sbjct: 1 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 60 Query: 86 LEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISI--ASQCPT 143 E Q++ S + HP++ + D+ L++L+E V S + ++++ AS+ Sbjct: 61 REQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVKVSSHVHTVTLPPASETFP 120 Query: 144 AGNSCLVSGWGLLANGRM---PTVLQCVNVSVVSEEVCSKLYD---------PLYHPSMF 191 G C V+GWG + N P L+ V V ++ +C Y + M Sbjct: 121 PGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDML 180 Query: 192 CAGGGHDQKDSCNGDSGGPLIC--NG-YLQ-GLVSFGKAPCGQVGVPGVYTNLCKFTEWI 247 CA G+ ++DSC GDSGGPL+C NG +LQ G+VS+G+ C Q PG+YT + + +WI Sbjct: 181 CA--GNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEG-CAQPNRPGIYTRVTYYLDWI 237 Query: 248 EKTV 251 V Sbjct: 238 HHYV 241 >6I44-A nrPDB Length = 627 Score = 116 bits (291), Expect = 8e-27, Method: Compositional matrix adjust. Identities = 84/249 (33%), Positives = 128/249 (51%), Gaps = 22/249 (8%) Query: 24 VSGSCSQIINGEDCSPHSQPWQAALVME---NELFCSGVLVHPQWVLSAAHCF-----QN 75 + + ++I+ G S PWQ +L ++ C G L+ QWVL+AAHCF Q+ Sbjct: 373 TTKTSTRIVGGTQSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQD 432 Query: 76 SYTIGLGLHSLE--ADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIR 133 + I G+ L P SQ+ E + H Y +D+ LIKL + ++ + Sbjct: 433 VWRIYSGILQLSDITKDTPFSQIKEI---IIHQNYKVSEGNHDIALIKLQAPLQYTEFQK 489 Query: 134 SISIASQCPTAG--NSCLVSGWGLLAN-GRMPTVLQCVNVSVVSEEVCSKLY-DPLYHPS 189 I + S+ T+ +C V+GWG A G + +LQ VN+ +V+ E C K Y D Sbjct: 490 PICLPSKGDTSTIYTNCWVTGWGFSAEAGEIQNILQKVNIPLVTNEECQKRYQDYKITQR 549 Query: 190 MFCAGGGHDQKDSCNGDSGGPLIC--NG--YLQGLVSFGKAPCGQVGVPGVYTNLCKFTE 245 M CAG KD+C GD+GGPL+C NG L G+ S+G+ C + PGVYT + ++ + Sbjct: 550 MVCAGYKEGGKDACKGDAGGPLVCKHNGMWRLVGITSWGEG-CARREQPGVYTKVAEYMD 608 Query: 246 WIEKTVQAS 254 WI + Q+S Sbjct: 609 WILEKTQSS 617 >1LTO-A nrPDB Length = 245 Score = 116 bits (291), Expect = 9e-27, Method: Compositional matrix adjust. Identities = 79/246 (32%), Positives = 124/246 (50%), Gaps = 30/246 (12%) Query: 31 IINGEDCSPHSQPWQAALVMENEL---FCSGVLVHPQWVLSAAHCF----QNSYTIGLGL 83 I+ G++ PWQ +L + + FC G L+HPQWVL+AAHC ++ T+ + L Sbjct: 1 IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCLGPDVKDLATLRVQL 60 Query: 84 HSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISI--ASQC 141 + Q++ S + HP++ D+ L++L+E V+ S + ++ + AS+ Sbjct: 61 REQHLYYQ--DQLLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSRVHTVMLPPASET 118 Query: 142 PTAGNSCLVSGWGLLANGR---MPTVLQCVNVSVVSEEVCSKLYD---------PLYHPS 189 G C V+GWG + N P L+ V V ++ +C Y + Sbjct: 119 FPPGMPCWVTGWGDVDNDEPLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIIRDD 178 Query: 190 MFCAGGGHDQKDSCNGDSGGPLIC--NG-YLQ-GLVSFGKAPCGQVGVPGVYTNLCKFTE 245 M CAG Q+DSC GDSGGPL+C NG +LQ G+VS+ + C Q PG+YT + + + Sbjct: 179 MLCAGNS--QRDSCKGDSGGPLVCKVNGTWLQAGVVSWDEG-CAQPNRPGIYTRVTYYLD 235 Query: 246 WIEKTV 251 WI V Sbjct: 236 WIHHYV 241 >5LHN-A nrPDB Length = 247 Score = 116 bits (290), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 86/251 (34%), Positives = 125/251 (49%), Gaps = 35/251 (13%) Query: 31 IINGEDCSPHSQPWQAALVMENE------LFCSGVLVHPQWVLSAAHCF-----QNSYTI 79 I+ GE +QPW AA+ +N+ C G L+ P WV SAAHCF + +Y + Sbjct: 1 IVGGEFTEVENQPWFAAIYQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVV 60 Query: 80 GLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLA--NDLMLIKLDESVSE----SDTIR 133 LG S E+ PG E + H Y LA ND+ L+K+ S + S +I+ Sbjct: 61 YLG-QSKESSYNPGEMKFEVEQLILHEYYREDSLAYHNDIALLKIRTSTGQCAQPSRSIQ 119 Query: 134 SISIASQCPTA--GNSCLVSGWGLLANGRM--PTVLQCVNVSVVSEEVCSKLYDPLYHPS 189 +I++ + A G+ C ++G+G + P L+ V +VS E C + P Y+ S Sbjct: 120 TIALPPRFTDAPFGSDCEITGFGKESESDYLYPKNLKMSVVKLVSHEQCMQ---PHYYGS 176 Query: 190 -----MFCAGGGHDQKDSCNGDSGGPLICN----GYLQGLVSFGKAPCGQVGVPGVYTNL 240 M CA + DSC GDSGGPLICN L G+VS+G+ C + PGVYT + Sbjct: 177 EINYKMLCAADPEWKTDSCKGDSGGPLICNIEGRPTLSGIVSWGRG-CAEKNKPGVYTRV 235 Query: 241 CKFTEWIEKTV 251 F +WI+ + Sbjct: 236 SHFLDWIQSHI 246 >1AE5-A nrPDB Length = 225 Score = 115 bits (289), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 72/225 (32%), Positives = 111/225 (49%), Gaps = 18/225 (8%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSY----TIGLGLHSL 86 I+ G P P+ A++ + FC G L+H ++V++AA CFQ+ T+ LG + L Sbjct: 1 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 60 Query: 87 EADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDE--SVSESDTIRSISIASQCPTA 144 + Q S S+ Y+ NDLML++LD +++ S TI + + + A Sbjct: 61 RRRERQSRQTFSIS-SMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEA 119 Query: 145 GNSCLVSGWG-LLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSC 203 G C V+GWG + GR+ + VNV+V E+ C P+ C G + C Sbjct: 120 GTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC--------RPNNVCTGVLTRRGGIC 171 Query: 204 NGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIE 248 NGD G PL+C G G+ SF PCG+ P +T + F +WI+ Sbjct: 172 NGDGGTPLVCEGLAHGVASFSLGPCGR--GPDFFTRVALFRDWID 214 >2F91-A nrPDB Length = 237 Score = 115 bits (288), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 78/235 (33%), Positives = 119/235 (50%), Gaps = 19/235 (8%) Query: 31 IINGEDCS----PHSQPWQAALVMENELFCSGVLVHPQWVLSAAHC-FQNSYTIGLGLHS 85 I+ G D + P+ +Q + + FC + + + ++A HC + + Y GL Sbjct: 1 IVGGTDATLGEFPYQLSFQETFIGFSFHFCGASIYNENYAITAGHCVYGDDYENPSGLQI 60 Query: 86 LEAD-----QEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQ 140 + + E Q++ S + H ++ LL ND+ L+KL S++ +D + I++ Q Sbjct: 61 VAGELDMSVNEGSEQIITVSKIILHENFDYNLLDNDISLLKLSGSLTFNDNVAPIALPEQ 120 Query: 141 CPTAGNSCLVSGWGLLAN-GRMPTVLQCVNVSVVSEEVCSKLY--DPLYHPSMFCAGGGH 197 TA +V+GWG + G P VLQ V V +VS+E C Y D + SM CAG Sbjct: 121 GHTATGDVIVTGWGTTSEGGNTPDVLQKVTVPLVSDEDCRADYGADEILD-SMICAGVPE 179 Query: 198 DQKDSCNGDSGGPLICNG----YLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIE 248 KDSC GDSGGPL + YL G+VS+G C + G PGVYT + +WI+ Sbjct: 180 GGKDSCQGDSGGPLAASDTGSTYLAGIVSWGYG-CARPGYPGVYTEVSYHVDWIK 233 >3F6U-H nrPDB Length = 240 Score = 115 bits (288), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 74/240 (30%), Positives = 119/240 (49%), Gaps = 19/240 (7%) Query: 31 IINGEDCSPHSQPWQAALV-MENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEAD 89 +I+G+ PWQ L+ + +L C VL+HP WVL+AAHC S + + L + Sbjct: 1 LIDGKMTRRGDSPWQVVLLDSKKKLACGAVLIHPSWVLTAAHCMDESKKLLVRLGEYDLR 60 Query: 90 Q-EPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISI------ASQCP 142 + E ++ HP Y++ ND+ L+ L + + S TI I + + Sbjct: 61 RWEKWELDLDIKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPICLPDSGLAERELN 120 Query: 143 TAGNSCLVSGWGLL------ANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGG 196 AG LV+GWG A VL + + VV CS++ + +M CAG Sbjct: 121 QAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSNMVSENMLCAGIL 180 Query: 197 HDQKDSCNGDSGGPLICN----GYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 252 D++D+C GDSGGP++ + +L GLVS+G+ CG + GVYT + ++ +WI ++ Sbjct: 181 GDRQDACEGDSGGPMVASFHGTWFLVGLVSWGEG-CGLLHNYGVYTKVSRYLDWIHGHIR 239 >1EKB-B nrPDB Length = 235 Score = 114 bits (286), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 79/233 (33%), Positives = 114/233 (48%), Gaps = 17/233 (7%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQ------NSYTIGLGLH 84 I+ G D + PW AL +++ C LV W++SAAHC + + LGLH Sbjct: 1 IVGGSDSREGAWPWVVALYFDDQQVCGASLVSRDWLVSAAHCVYGRNMEPSKWKAVLGLH 60 Query: 85 SLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISI--ASQCP 142 P + V +P YN+ ND+ ++ L+ V+ +D I+ I + +Q Sbjct: 61 MASNLTSPQIETRLIDQIVINPHYNKRRKNNDIAMMHLEMKVNYTDYIQPICLPEENQVF 120 Query: 143 TAGNSCLVSGWG-LLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYH--PSMFCAGGGHDQ 199 G C ++GWG L+ G VLQ +V ++S E C + P Y+ +M CAG Sbjct: 121 PPGRICSIAGWGALIYQGSTADVLQEADVPLLSNEKCQQQM-PEYNITENMVCAGYEAGG 179 Query: 200 KDSCNGDSGGPLICNG----YLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIE 248 DSC GDSGGPL+C L G+ SFG C PGVY + +FTEWI+ Sbjct: 180 VDSCQGDSGGPLMCQENNRWLLAGVTSFGYQ-CALPNRPGVYARVPRFTEWIQ 231 >5GVT-A nrPDB Length = 250 Score = 114 bits (285), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 79/242 (32%), Positives = 121/242 (50%), Gaps = 22/242 (9%) Query: 31 IINGEDCSPHSQPWQAAL---VMENELFCSGVLVHPQWVLSAAHCFQ-----NSYTIGLG 82 I+ G + S PWQ +L ++ C G ++ QWVL+AAHCF + + I G Sbjct: 1 IVGGTNASLGEWPWQVSLQVKLVSQTHLCGGSIIGRQWVLTAAHCFDGIPYPDVWRIYGG 60 Query: 83 LHSLE--ADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQ 140 + SL + P S++ E + H EY D+ LIKL ++ ++ + IS+ S+ Sbjct: 61 ILSLSEITKETPSSRIKEL---IIHQEYKVSEGNYDIALIKLQTPLNYTEFQKPISLPSK 117 Query: 141 CPTAG--NSCLVSGWGLLA-NGRMPTVLQCVNVSVVSEEVCSKLY-DPLYHPSMFCAGGG 196 T +C V+GWG G +LQ + +V E C K Y D + + M CAG Sbjct: 118 ADTNTIYTNCWVTGWGYTKEQGETQNILQKATIPLVPNEECQKKYRDYVINKQMICAGYK 177 Query: 197 HDQKDSCNGDSGGPLICNG----YLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 252 D+C GDSGGPL+C L G+ S+G+ C + PGVYT + ++ +WI + Q Sbjct: 178 EGGTDACKGDSGGPLVCKHSGRWQLVGITSWGEG-CARKDQPGVYTKVSEYMDWILEKTQ 236 Query: 253 AS 254 +S Sbjct: 237 SS 238 >3K65-B nrPDB Length = 308 Score = 113 bits (283), Expect = 6e-26, Method: Compositional matrix adjust. Identities = 80/256 (31%), Positives = 119/256 (46%), Gaps = 35/256 (13%) Query: 30 QIINGEDCSPHSQPWQAALVMEN--ELFCSGVLVHPQWVLSAAHCF----------QNSY 77 +I+ G D PWQ L ++ EL C L+ +WVL+AAHC +N Sbjct: 49 RIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 108 Query: 78 TIGLGLHSLEADQEPGSQMVEASLSVRHPEYN-RPLLANDLMLIKLDESVSESDTIRSI- 135 + +G HS + ++ HP YN R L D+ L+KL + V+ SD I + Sbjct: 109 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVC 168 Query: 136 ----SIASQCPTAGNSCLVSGWGLLAN------GR-MPTVLQCVNVSVVSEEVCSKLYDP 184 A+ AG V+GWG L G+ P+VLQ VN+ +V VC Sbjct: 169 LPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRI 228 Query: 185 LYHPSMFCAGGGHDQ---KDSCNGDSGGPLICNG------YLQGLVSFGKAPCGQVGVPG 235 +MFCAG D+ D+C GD+GGP + Y G+VS+G+ C + G G Sbjct: 229 RITDNMFCAGYKPDEGKRGDACEGDAGGPFVMKSPFNNRWYQMGIVSWGEG-CDRDGKYG 287 Query: 236 VYTNLCKFTEWIEKTV 251 YT++ + +WI+K + Sbjct: 288 FYTHVFRLKKWIQKVI 303 >3NXP-A nrPDB Length = 424 Score = 113 bits (283), Expect = 7e-26, Method: Compositional matrix adjust. Identities = 81/256 (31%), Positives = 119/256 (46%), Gaps = 35/256 (13%) Query: 30 QIINGEDCSPHSQPWQAALVMEN--ELFCSGVLVHPQWVLSAAHCF----------QNSY 77 +I+ G D PWQ L ++ EL C L+ +WVL+AAHC +N Sbjct: 165 RIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 224 Query: 78 TIGLGLHSLEADQEPGSQMVEASLSVRHPEYN-RPLLANDLMLIKLDESVSESDTIRSI- 135 + +G HS + ++ HP YN R L D+ L+KL + V+ SD I + Sbjct: 225 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVC 284 Query: 136 ----SIASQCPTAGNSCLVSGWGLLAN------GR-MPTVLQCVNVSVVSEEVCSKLYDP 184 A+ AG V+GWG L G+ P+VLQ VN+ +V VC Sbjct: 285 LPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRI 344 Query: 185 LYHPSMFCAGGGHDQ---KDSCNGDSGGPLICNG------YLQGLVSFGKAPCGQVGVPG 235 +MFCAG D+ D+C GDSGGP + Y G+VS+G+ C + G G Sbjct: 345 RITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEG-CDRDGKYG 403 Query: 236 VYTNLCKFTEWIEKTV 251 YT++ + +WI+K + Sbjct: 404 FYTHVFRLKKWIQKVI 419 >2OLG-A nrPDB Length = 278 Score = 113 bits (282), Expect = 8e-26, Method: Compositional matrix adjust. Identities = 80/261 (30%), Positives = 126/261 (48%), Gaps = 41/261 (15%) Query: 29 SQIINGEDCSPHSQPWQAALVMEN-----ELFCSGVLVHPQWVLSAAHCFQ--------- 74 +I+NG+D P PW A + +N + C G L++ +++++AAHC Sbjct: 21 DKILNGDDTVPEEFPWTAMIGYKNSSNFEQFACGGSLINNRYIVTAAHCVAGRVLRVVGA 80 Query: 75 -NSYTIGLGLHSLEAD----------QEPGSQMVEASLSVRHPEY--NRPLLANDLMLIK 121 N +G + + D +P +E + ++HP+Y +D+ LI+ Sbjct: 81 LNKVRLGEWNTATDPDCYGAVRVCVPDKPIDLGIEET--IQHPDYVDGSKDRYHDIALIR 138 Query: 122 LDESVSESDTIRSISIA--SQCPTAGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCS 179 L+ V ++ IR + + ++ G V GWG G+ T+ Q + V VV E C+ Sbjct: 139 LNRQVEFTNYIRPVCLPQPNEEVQVGQRLTVVGWGRTETGQYSTIKQKLAVPVVHAEQCA 198 Query: 180 KLYDP---LYHPSMFCAGGGHDQKDSCNGDSGGPLICNG-----YLQGLVSFGKAPCGQV 231 K + S CAGG KDSC GDSGGPL+ +L+GLVSFG A CG Sbjct: 199 KTFGAAGVRVRSSQLCAGG-EKAKDSCGGDSGGPLLAERANQQFFLEGLVSFG-ATCGTE 256 Query: 232 GVPGVYTNLCKFTEWIEKTVQ 252 G PG+YT + K+ +WIE ++ Sbjct: 257 GWPGIYTKVGKYRDWIEGNIR 277 >2XXL-A nrPDB Length = 408 Score = 112 bits (281), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 80/256 (31%), Positives = 121/256 (47%), Gaps = 35/256 (13%) Query: 30 QIINGEDCSPHSQPWQAALVM----ENELFCSGVLVHPQWVLSAAHC---FQNS-YTIGL 81 ++ NG + S+PW A L E+ C G ++ +++L+AAHC QN Y I L Sbjct: 118 RVSNGYEVKLSSRPWMALLRYQQFGESRFLCGGAMISERYILTAAHCVHGLQNDLYEIRL 177 Query: 82 GLHSLEADQE-----------PGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESD 130 G H + +++ P V + H +Y+ + +D+ L+KL+ SV Sbjct: 178 GEHRISTEEDCRQQGRKKKCAPPVVNVGIEKHLIHEKYDARHIMHDIALLKLNRSVPFQK 237 Query: 131 TIRSISIA-----SQCPTAGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYDPL 185 I+ I + + ++ V+GWG NG VL NV + CS+ Y Sbjct: 238 HIKPICLPITDELKEKAEQISTYFVTGWGTTENGSSSDVLLQANVPLQPRSACSQAYRRA 297 Query: 186 YHPSMFCAGGGHDQKDSCNGDSGGPLICNG-YLQ---------GLVSFGKAPCGQVGVPG 235 S C GGG D +DSC GDSGGPL YL G+VS G CGQ+ +PG Sbjct: 298 VPLSQLCVGGG-DLQDSCKGDSGGPLQAPAQYLGEYAPKMVEFGIVSQGVVTCGQISLPG 356 Query: 236 VYTNLCKFTEWIEKTV 251 +YTN+ ++ +WI T+ Sbjct: 357 LYTNVGEYVQWITDTM 372 >4NZQ-A nrPDB Length = 557 Score = 112 bits (281), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 81/256 (31%), Positives = 119/256 (46%), Gaps = 35/256 (13%) Query: 30 QIINGEDCSPHSQPWQAALVMEN--ELFCSGVLVHPQWVLSAAHCF----------QNSY 77 +I+ G D PWQ L ++ EL C L+ +WVL+AAHC +N Sbjct: 298 RIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 357 Query: 78 TIGLGLHSLEADQEPGSQMVEASLSVRHPEYN-RPLLANDLMLIKLDESVSESDTIRSI- 135 + +G HS + ++ HP YN R L D+ L+KL + V+ SD I + Sbjct: 358 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVC 417 Query: 136 ----SIASQCPTAGNSCLVSGWGLLAN------GR-MPTVLQCVNVSVVSEEVCSKLYDP 184 A+ AG V+GWG L G+ P+VLQ VN+ +V VC Sbjct: 418 LPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRI 477 Query: 185 LYHPSMFCAGGGHDQ---KDSCNGDSGGPLICNG------YLQGLVSFGKAPCGQVGVPG 235 +MFCAG D+ D+C GDSGGP + Y G+VS+G+ C + G G Sbjct: 478 RITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEG-CDRDGKYG 536 Query: 236 VYTNLCKFTEWIEKTV 251 YT++ + +WI+K + Sbjct: 537 FYTHVFRLKKWIQKVI 552 >3P8G-A nrPDB Length = 241 Score = 112 bits (280), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 76/240 (31%), Positives = 108/240 (45%), Gaps = 20/240 (8%) Query: 31 IINGEDCSPHSQPWQAAL-VMENELFCSGVLVHPQWVLSAAHCFQNS----------YTI 79 ++ G D PWQ +L + C L+ P W++SAAHC+ + +T Sbjct: 1 VVGGTDADEGEWPWQVSLHALGQGHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQWTA 60 Query: 80 GLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISI-- 137 LGLH PG Q + HP +N D+ L++L++ S +R I + Sbjct: 61 FLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALLELEKPAEYSSMVRPICLPD 120 Query: 138 ASQCPTAGNSCLVSGWGLLA-NGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGG 196 AS AG + V+GWG G +LQ + V+ + C L P M C G Sbjct: 121 ASHVFPAGKAIWVTGWGHTQYGGTGALILQKGEIRVIQQTTCENLLPQQITPRMMCVGFL 180 Query: 197 HDQKDSCNGDSGGPLI---CNG--YLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 251 DSC GDSGGPL +G + G+VS+G C Q PGVYT L F +WI++ Sbjct: 181 SGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWGDG-CAQRNKPGVYTRLPLFRDWIKENT 239 >1FUJ-A nrPDB Length = 221 Score = 112 bits (279), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 75/232 (32%), Positives = 111/232 (47%), Gaps = 21/232 (9%) Query: 31 IINGEDCSPHSQPWQAALVMENE---LFCSGVLVHPQWVLSAAHCF----QNSYTIGLGL 83 I+ G + PHS+P+ A+L M FC G L+HP +VL+AAHC Q + LG Sbjct: 1 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 60 Query: 84 HSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPT 143 H++ QEP Q + V Y+ ND++LI+L + S ++ ++ + Q Sbjct: 61 HNVRT-QEPTQQHFSVA-QVFLNNYDAENKLNDILLIQLSSPANLSASVATVQLPQQDQP 118 Query: 144 A--GNSCLVSGWGLLANGRMPT-VLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQK 200 G CL GWG + P VLQ +NV+VV+ P C + Sbjct: 119 VPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTF---------FCRPHNICTFVPRRKA 169 Query: 201 DSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 252 C GDSGGPLIC+G +QG+ SF C P +T + + +WI T++ Sbjct: 170 GICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 221 >3W94-A nrPDB Length = 235 Score = 112 bits (279), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 72/236 (30%), Positives = 114/236 (48%), Gaps = 15/236 (6%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNS------YTIGLGLH 84 ++ G + + PW +L C L+ W+L+AAHC ++ LGLH Sbjct: 1 VVGGVNAEKGAWPWMVSLHWRGRHGCGASLIGRDWLLTAAHCVYGKNTHLQYWSAVLGLH 60 Query: 85 SLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIAS--QCP 142 + + Q+ + + + YNR D+ ++ L + V+ ++ + + +AS Q Sbjct: 61 AQSSMNSQEVQIRQVDRIIINKNYNRRTKEADIAMMHLQQPVNFTEWVLPVCLASEDQHF 120 Query: 143 TAGNSCLVSGWGLLANG-RMPTVLQCVNVSVVSEEVCSKLY-DPLYHPSMFCAGGGHDQK 200 AG C ++GWG A G +P +LQ V +V ++ C +L + + SM CAG Sbjct: 121 PAGRRCFIAGWGRDAEGGSLPDILQEAEVPLVDQDECQRLLPEYTFTSSMLCAGYPEGGV 180 Query: 201 DSCNGDSGGPLIC----NGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 252 DSC GDSGGPL+C L G+ SFG CG+ PG Y + FT WI +T + Sbjct: 181 DSCQGDSGGPLMCLEDARWTLIGVTSFGVG-CGRPERPGAYARVSAFTSWIAETRR 235 >1YC0-A nrPDB Length = 283 Score = 112 bits (279), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 86/248 (34%), Positives = 132/248 (53%), Gaps = 33/248 (13%) Query: 30 QIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCF-----QNSYTIGLGLH 84 +II G P S PW AA+ + + FC+G LVH WV+SAAHCF ++S ++ LG H Sbjct: 35 RIIGGSSSLPGSHPWLAAIYIGDS-FCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQH 93 Query: 85 ----SLEADQEPG-SQMVEASL-SVRHPEYNRPLLANDLMLIKL----DESVSESDTIRS 134 + + Q G + + +L SV +P +DL+LI+L D + S ++ Sbjct: 94 FFNRTTDVTQTFGIEKYIPYTLYSVFNPS------DHDLVLIRLKKKGDRCATRSQFVQP 147 Query: 135 ISIASQCPT--AGNSCLVSGWGLLANGR--MPTVLQCVNVSVVSEEVCS--KLYDPLYHP 188 I + T AG+ C ++GWG L + L+ V +V++ CS ++Y P Sbjct: 148 ICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISP 207 Query: 189 SMFCAGGGHDQKDSCNGDSGGPLIC--NG--YLQGLVSFGKAPCGQVGVPGVYTNLCKFT 244 +M CAG + D+C GDSGGPL C NG YL G++S+G CG++ PGVYT + + Sbjct: 208 NMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDG-CGRLHKPGVYTRVANYV 266 Query: 245 EWIEKTVQ 252 +WI ++ Sbjct: 267 DWINDRIR 274 >2PKA-B nrPDB Length = 152 Score = 111 bits (278), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 53/142 (37%), Positives = 81/142 (57%), Gaps = 4/142 (2%) Query: 114 ANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLVSGWGLLANG----RMPTVLQCVN 169 ++DLML++L +D ++ + + +Q P G++C SGWG + G P +QCV Sbjct: 7 SHDLMLLRLQSPAKITDAVKVLELPTQEPELGSTCEASGWGSIEPGPDDFEFPDEIQCVQ 66 Query: 170 VSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCG 229 ++++ C+ + SM CAG KD+C GDSGGPLICNG QG+ S+G PCG Sbjct: 67 LTLLQNTFCADAHPDKVTESMLCAGYLPGGKDTCMGDSGGPLICNGMWQGITSWGHTPCG 126 Query: 230 QVGVPGVYTNLCKFTEWIEKTV 251 P +YT L + +WI+ T+ Sbjct: 127 SANKPSIYTKLIFYLDWIDDTI 148 >2OCV-B nrPDB Length = 259 Score = 111 bits (277), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 81/255 (31%), Positives = 116/255 (45%), Gaps = 35/255 (13%) Query: 31 IINGEDCSPHSQPWQAALVMEN--ELFCSGVLVHPQWVLSAAHCF----------QNSYT 78 I+ G D PWQ L ++ EL C L+ +WVL+AAHC +N Sbjct: 1 IVEGWDAEKGIAPWQVMLFRKSPQELLCGASLISDRWVLTAAHCILYPPWDKNFTENDLL 60 Query: 79 IGLGLHSLEADQEPGSQMVEASLSVRHPEYN-RPLLANDLMLIKLDESVSESDTIRSISI 137 + +G HS + ++ HP YN R L D+ L+KL + V SD I + + Sbjct: 61 VRIGKHSRTRYERNVEKISMLEKIYVHPRYNWRENLDRDIALLKLKKPVPFSDYIHPVCL 120 Query: 138 ASQCPT-----AGNSCLVSGWGLLA-------NGRMPTVLQCVNVSVVSEEVCSKLYDPL 185 + AG V+GWG L N P+VLQ VN+ +V VC Sbjct: 121 PDKQTVTSLLRAGYKGRVTGWGNLRETWTTNINEIQPSVLQVVNLPIVERPVCKASTRIR 180 Query: 186 YHPSMFCAGGG-HDQK--DSCNGDSGGPLICNG------YLQGLVSFGKAPCGQVGVPGV 236 +MFCAG +D K D+C GDSGGP + Y G+VS+G+ C + G G Sbjct: 181 ITDNMFCAGFKVNDTKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEG-CDRKGKYGF 239 Query: 237 YTNLCKFTEWIEKTV 251 YT++ + WI+K + Sbjct: 240 YTHVFRLKAWIQKVI 254 >2R0L-A nrPDB Length = 248 Score = 111 bits (277), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 86/247 (34%), Positives = 131/247 (53%), Gaps = 33/247 (13%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCF-----QNSYTIGLGLH- 84 II G P S PW AA+ + + FC+G LVH WV+SAAHCF ++S ++ LG H Sbjct: 1 IIGGSSSLPGSHPWLAAIYIGDS-FCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHF 59 Query: 85 ---SLEADQEPG-SQMVEASL-SVRHPEYNRPLLANDLMLIKL----DESVSESDTIRSI 135 + + Q G + + +L SV +P +DL+LI+L D + S ++ I Sbjct: 60 FNRTTDVTQTFGIEKYIPYTLYSVFNPS------DHDLVLIRLKKKGDRCATRSQFVQPI 113 Query: 136 SIASQCPT--AGNSCLVSGWGLLANGR--MPTVLQCVNVSVVSEEVCS--KLYDPLYHPS 189 + T AG+ C ++GWG L + L+ V +V++ CS ++Y P+ Sbjct: 114 CLPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPN 173 Query: 190 MFCAGGGHDQKDSCNGDSGGPLIC--NG--YLQGLVSFGKAPCGQVGVPGVYTNLCKFTE 245 M CAG + D+C GDSGGPL C NG YL G++S+G CG++ PGVYT + + + Sbjct: 174 MLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDG-CGRLHKPGVYTRVANYVD 232 Query: 246 WIEKTVQ 252 WI ++ Sbjct: 233 WINDRIR 239 >1FON-A nrPDB Length = 240 Score = 110 bits (275), Expect = 5e-25, Method: Compositional matrix adjust. Identities = 84/246 (34%), Positives = 120/246 (48%), Gaps = 30/246 (12%) Query: 33 NGEDCSPHSQPWQAALVMENE----LFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEA 88 NGED P+S WQ +L E + C G L+ P WV++A HC S T + L + Sbjct: 1 NGEDAVPYSWSWQVSLQYEKDGAFHHTCGGSLIAPDWVVTAGHCISTSRTYQVVLGEYDR 60 Query: 89 DQEPGSQMV---EASLSVRHPEYNRPLLA--NDLMLIKLDESVSESDTIRSISIASQCPT 143 GS+ V A HP +N +A ND+ L+KL S D ++ ++ P Sbjct: 61 SVLEGSEQVIPINAGDLFVHPLWNSNCVACGNDIALVKLSRSAQLGDKVQLANL----PP 116 Query: 144 AGN------SCLVSGWG-LLANGRMPTVLQCVNVSVVSEEVCSK--LYDPLYHPSMFCAG 194 AG+ C +SGWG L G +P LQ + V E CS+ + +M CAG Sbjct: 117 AGDILPNEAPCYISGWGRLYTGGPLPDKLQQALLPTVDYEHCSQWDWWGITVKKTMVCAG 176 Query: 195 GGHDQKDSCNGDSGGPLIC---NGYLQ--GLVSFGKA-PCGQVGVPGVYTNLCKFTEWIE 248 G D + CNGDSGGPL C +G Q G+ SF A C + P V+T + F +WI+ Sbjct: 177 G--DTRSGCNGDSGGPLNCPAADGSWQVHGVTSFVSAFGCNTIKKPTVFTRVSAFIDWID 234 Query: 249 KTVQAS 254 +T+ ++ Sbjct: 235 ETIASN 240 >5UGG-A nrPDB Length = 251 Score = 110 bits (275), Expect = 6e-25, Method: Compositional matrix adjust. Identities = 75/237 (31%), Positives = 113/237 (47%), Gaps = 22/237 (9%) Query: 30 QIINGEDCSPHSQPWQAALVMENEL-FCSGVLVHPQWVLSAAHCFQN-----SYTIGLGL 83 +++ G PHS PWQ +L + FC G L+ P+WVL+AAHC + SY + LG Sbjct: 21 RVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGA 80 Query: 84 HSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPT 143 H E + EP Q +E S P D+ L+KL +D + + S Sbjct: 81 HQ-EVNLEPHVQEIEVSRLFLEP------TRKDIALLKLSSPAVITDKVIPACLPSPNYV 133 Query: 144 AGNS--CLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSK--LYDPLYHPSMFCAGGGHDQ 199 + C ++GWG +L+ + V+ +VC++ + + CAG Sbjct: 134 VADRTECFITGWGETQGTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGG 193 Query: 200 KDSCNGDSGGPLIC---NGY-LQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 252 DSC GDSGGPL+C + Y LQG+ S+G C + PGVY + +F WIE ++ Sbjct: 194 TDSCQGDSGGPLVCFEKDKYILQGVTSWGLG-CARPNKPGVYVRVSRFVTWIEGVMR 249 >1C5M-D nrPDB Length = 255 Score = 110 bits (275), Expect = 6e-25, Method: Compositional matrix adjust. Identities = 65/236 (27%), Positives = 116/236 (49%), Gaps = 13/236 (5%) Query: 31 IINGEDCSPHSQPWQAALV-MENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEAD 89 I+ G++C PWQA L+ ENE FC G ++ ++L+AAHC + + + + Sbjct: 1 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTE 60 Query: 90 QEPGSQMV-EASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISI-----ASQCPT 143 QE G + V E + ++H + + D+ +++L ++ + + A Sbjct: 61 QEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLM 120 Query: 144 AGNSCLVSGWGLL-ANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDS 202 + +VSG+G GR T L+ + V V C + +MFCAG Q+D+ Sbjct: 121 TQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDA 180 Query: 203 CNGDSGGPLICNG----YLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 C GDSGGP + ++ G+VS+G+ C + G G+YT + F +WI+++++ Sbjct: 181 CQGDSGGPHVTRFKDTYFVTGIVSWGEG-CARKGKYGIYTKVTAFLKWIDRSMKTR 235 >1PPF-E nrPDB Length = 218 Score = 109 bits (273), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 73/229 (31%), Positives = 114/229 (49%), Gaps = 18/229 (7%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIG----LGLHSL 86 I+ G PH+ P+ +L + FC L+ P +V+SAAHC N LG H+L Sbjct: 1 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 60 Query: 87 EADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGN 146 + +EP Q V A + Y+ L ND+++++L+ S + + ++ + +Q GN Sbjct: 61 -SRREPTRQ-VFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGN 118 Query: 147 --SCLVSGWGLLANGR-MPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSC 203 CL GWGLL R + +VLQ +NV+VV+ +C + S C Q C Sbjct: 119 GVQCLAMGWGLLGRNRGIASVLQELNVTVVTS-LCRR--------SNVCTLVRGRQAGVC 169 Query: 204 NGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 252 GDSG PL+CNG + G+ SF + C P + + +F WI+ +Q Sbjct: 170 FGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 218 >5TO3-B nrPDB Length = 409 Score = 108 bits (271), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 82/256 (32%), Positives = 118/256 (46%), Gaps = 35/256 (13%) Query: 31 IINGEDCSPHSQPWQAALVMEN--ELFCSGVLVHPQWVLSAAHCF----------QNSYT 78 I+ G D PWQ L ++ EL C L+ +WVL+AAHC +N Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 79 IGLGLHSLEADQEPGSQMVEASLSVRHPEYN-RPLLANDLMLIKLDESVSESDTIRSISI 137 + +G HS + ++ HP YN R L D+ L+KL + V+ SD I + + Sbjct: 61 VRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCL 120 Query: 138 -----ASQCPTAGNSCLVSGWGLLAN------GR-MPTVLQCVNVSVVSEEVCSKLYDPL 185 A+ AG V+GWG L G+ P+VLQ VN+ +V VC Sbjct: 121 PDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIR 180 Query: 186 YHPSMFCAGGGHDQ---KDSCNGDSGGPLICNG------YLQGLVSFGKAPCGQVGVPGV 236 +MFCAG D+ D+C GDSGGP + Y G+VS G A C + G G Sbjct: 181 ITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSAG-AGCDRDGKYGF 239 Query: 237 YTNLCKFTEWIEKTVQ 252 YT++ + +WI+K + Sbjct: 240 YTHVFRLKKWIQKVID 255 >1MKW-K nrPDB Length = 308 Score = 108 bits (271), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 79/259 (30%), Positives = 120/259 (46%), Gaps = 41/259 (15%) Query: 30 QIINGEDCSPHSQPWQAALVMEN--ELFCSGVLVHPQWVLSAAHC-----FQNSYTIG-- 80 +I+ G+D PWQ L ++ EL C L+ +WVL+AAHC + ++T+ Sbjct: 49 RIVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDL 108 Query: 81 ---LGLHSLEADQEPGSQMVEASLSVRHPEYN-RPLLANDLMLIKLDESVSESDTIRSI- 135 +G HS + ++ HP YN + L D+ L+KL + SD I + Sbjct: 109 LVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVC 168 Query: 136 ----SIASQCPTAGNSCLVSGWGLLANGR----------MPTVLQCVNVSVVSEEVCSKL 181 A++ AG V+GWG N R P+VLQ VN+ +V VC Sbjct: 169 LPDKQTAAKLLHAGFKGRVTGWG---NRRETWTTSVAEVQPSVLQVVNLPLVERPVCKAS 225 Query: 182 YDPLYHPSMFCAG---GGHDQKDSCNGDSGGPLICNG------YLQGLVSFGKAPCGQVG 232 +MFCAG G + D+C GDSGGP + Y G+VS+G+ C + G Sbjct: 226 TRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWGEG-CDRDG 284 Query: 233 VPGVYTNLCKFTEWIEKTV 251 G YT++ + +WI+K + Sbjct: 285 KYGFYTHVFRLKKWIQKVI 303 >1SC8-U nrPDB Length = 262 Score = 108 bits (270), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 82/248 (33%), Positives = 118/248 (47%), Gaps = 34/248 (13%) Query: 30 QIINGEDCSPHSQPWQAALVMENE-----LFCSGVLVHPQWVLSAAHCF-----QNSYTI 79 +II GE + +QPW AA+ + C G L+ P WV+SA HCF + Y + Sbjct: 15 KIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIV 74 Query: 80 GLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLA--NDLMLIKLDES----VSESDTIR 133 LG L ++ + G E + H +Y+ LA ND+ L+K+ S TI+ Sbjct: 75 YLGRSRLNSNTQ-GEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQ 133 Query: 134 SISIASQC--PTAGNSCLVSGWGLL--ANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPS 189 +IS+ S P G SC ++G+G + P L+ V ++S C + P Y+ S Sbjct: 134 TISLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQ---PHYYGS 190 Query: 190 -----MFCAGGGHDQKDSCNGDSGGPLIC----NGYLQGLVSFGKAPCGQVGVPGVYTNL 240 M CA + DSC GDSGGPL+C L G+VS+G+ C PGVYT + Sbjct: 191 EVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRG-CALKDKPGVYTRV 249 Query: 241 CKFTEWIE 248 F WI Sbjct: 250 SHFLPWIR 257 >1ETT-H nrPDB Length = 259 Score = 108 bits (270), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 79/258 (30%), Positives = 120/258 (46%), Gaps = 41/258 (15%) Query: 31 IINGEDCSPHSQPWQAALVMEN--ELFCSGVLVHPQWVLSAAHC-----FQNSYTIG--- 80 I+ G+D PWQ L ++ EL C L+ +WVL+AAHC + ++T+ Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDLL 60 Query: 81 --LGLHSLEADQEPGSQMVEASLSVRHPEYN-RPLLANDLMLIKLDESVSESDTIRSISI 137 +G HS + ++ HP YN + L D+ L+KL + SD I + + Sbjct: 61 VRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVCL 120 Query: 138 -----ASQCPTAGNSCLVSGWGLLANGR----------MPTVLQCVNVSVVSEEVCSKLY 182 A++ AG V+GWG N R P+VLQ VN+ +V VC Sbjct: 121 PDKQTAAKLLHAGFKGRVTGWG---NRRETWTTSVAEVQPSVLQVVNLPLVERPVCKAST 177 Query: 183 DPLYHPSMFCAG---GGHDQKDSCNGDSGGPLICNG------YLQGLVSFGKAPCGQVGV 233 +MFCAG G + D+C GDSGGP + Y G+VS+G+ C + G Sbjct: 178 RIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWGEG-CDRDGK 236 Query: 234 PGVYTNLCKFTEWIEKTV 251 G YT++ + +WI+K + Sbjct: 237 YGFYTHVFRLKKWIQKVI 254 >5O32-I nrPDB Length = 244 Score = 107 bits (268), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 74/237 (31%), Positives = 113/237 (47%), Gaps = 19/237 (8%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 I+ G+ PWQ A+ + + C G+ + W+L+AAHC + S T + + D Sbjct: 1 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 60 Query: 91 -EPGSQMVEASLSVR---HPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTA-- 144 P + + R H YN ND+ LI++ + ++ D SI + P + Sbjct: 61 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 120 Query: 145 ----GNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLY-DPLYHPSMFCAGGGHDQ 199 ++C+VSGWG + LQ V ++S CSK Y + Y M CAG Sbjct: 121 LFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISN--CSKFYGNRFYEKEMECAGTYDGS 178 Query: 200 KDSCNGDSGGPLICNG-----YLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 251 D+C GDSGGPL+C Y+ G+VS+G+ CG+ PGVYT + + +WI V Sbjct: 179 IDACKGDSGGPLVCMDANNVTYVWGVVSWGEN-CGKPEFPGVYTKVANYFDWISYHV 234 >1P57-B nrPDB Length = 255 Score = 107 bits (268), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 76/244 (31%), Positives = 107/244 (43%), Gaps = 23/244 (9%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLE--- 87 I+ G D S PWQ +L + C G L+ WVL+AAHCF + Sbjct: 1 IVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAV 60 Query: 88 ADQEPGSQMVEASLSVRHPEY------NRPLLANDLMLIKLDESVSESDTIRSISI--AS 139 A P + V H Y N +ND+ L+ L + ++ I+ + + A Sbjct: 61 AQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAG 120 Query: 140 QCPTAGNSCLVSGWG-LLANGRMPTVLQCVNVSVVSEEVC--SKLYDPLYHPSMFCAGGG 196 Q G C V+GWG G+ VLQ V ++S +VC + Y P MFCAG Sbjct: 121 QALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGYP 180 Query: 197 HDQKDSCNGDSGGPLICNGYLQ--------GLVSFGKAPCGQVGVPGVYTNLCKFTEWIE 248 D+C GDSGGP +C + G+VS+G C PGVYT + F EWI Sbjct: 181 EGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTG-CALAQKPGVYTKVSDFREWIF 239 Query: 249 KTVQ 252 + ++ Sbjct: 240 QAIK 243 >4IGD-A nrPDB Length = 406 Score = 107 bits (267), Expect = 5e-24, Method: Compositional matrix adjust. Identities = 77/252 (30%), Positives = 111/252 (44%), Gaps = 32/252 (12%) Query: 29 SQIINGEDCSPHSQPWQAALVMEN-ELFCSGVLVHPQWVLSAAHCFQNS----------- 76 +QI NG + PW A L N + FC G L+ W+++AAHC S Sbjct: 154 AQIFNGRPAQKGTTPWIAMLSHLNGQPFCGGSLLGSSWIVTAAHCLHQSLDPEDPTLRDS 213 Query: 77 -------YTIGLGLH-SLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSE 128 + I LG H L +D+ Q + + HP+Y+ ND+ L++L ES Sbjct: 214 DLLSPSDFKIILGKHWRLRSDE--NEQHLGVKHTTLHPQYDPNTFENDVALVELLESPVL 271 Query: 129 SDTIRSISIASQCPTAGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHP 188 + + I + G +VSGWG R P L + + +V C K Y PL Sbjct: 272 NAFVMPICLPEGPQQEGAMVIVSGWGKQFLQRFPETLMEIEIPIVDHSTCQKAYAPLKKK 331 Query: 189 ---SMFCAGGGHDQKDSCNGDSGGPLIC------NGYLQGLVSFGKAPCGQVGVPGVYTN 239 M CAG KD+C GDSGGP++ YL G VS+G CG+ GVY+ Sbjct: 332 VTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGDD-CGKKDRYGVYSY 390 Query: 240 LCKFTEWIEKTV 251 + +WI++ Sbjct: 391 IHHNKDWIQRVT 402 >3T2N-A nrPDB Length = 372 Score = 107 bits (267), Expect = 5e-24, Method: Compositional matrix adjust. Identities = 77/246 (31%), Positives = 108/246 (43%), Gaps = 23/246 (9%) Query: 29 SQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLE- 87 +I+ G D S PWQ +L + C G L+ WVL+AAHCF + Sbjct: 116 DRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAG 175 Query: 88 --ADQEPGSQMVEASLSVRHPEY------NRPLLANDLMLIKLDESVSESDTIRSISI-- 137 A P + V H Y N +ND+ L+ L + ++ I+ + + Sbjct: 176 AVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPA 235 Query: 138 ASQCPTAGNSCLVSGWG-LLANGRMPTVLQCVNVSVVSEEVC--SKLYDPLYHPSMFCAG 194 A Q G C V+GWG G+ VLQ V ++S +VC + Y P MFCAG Sbjct: 236 AGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAG 295 Query: 195 GGHDQKDSCNGDSGGPLICNG--------YLQGLVSFGKAPCGQVGVPGVYTNLCKFTEW 246 D+C GDSGGP +C L G+VS+G C PGVYT + F EW Sbjct: 296 YPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTG-CALAQKPGVYTKVSDFREW 354 Query: 247 IEKTVQ 252 I + ++ Sbjct: 355 IFQAIK 360 >4DUR-A nrPDB Length = 791 Score = 106 bits (265), Expect = 8e-24, Method: Compositional matrix adjust. Identities = 75/233 (32%), Positives = 111/233 (47%), Gaps = 22/233 (9%) Query: 30 QIINGEDCSPHSQPWQAALVMENEL-FCSGVLVHPQWVLSAAHCFQN-----SYTIGLGL 83 +++ G PHS PWQ +L + FC G L+ P+WVL+AAHC + SY + LG Sbjct: 561 RVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGA 620 Query: 84 HSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPT 143 H E + EP Q +E S P D+ L+KL +D + + S Sbjct: 621 HQ-EVNLEPHVQEIEVSRLFLEP------TRKDIALLKLSSPAVITDKVIPACLPSPNYV 673 Query: 144 AGN--SCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSK--LYDPLYHPSMFCAGGGHDQ 199 + C ++GWG +L+ + V+ +VC++ + + CAG Sbjct: 674 VADRTECFITGWGETQGTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGG 733 Query: 200 KDSCNGDSGGPLIC---NGY-LQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIE 248 DSC GDSGGPL+C + Y LQG+ S+G C + PGVY + +F WIE Sbjct: 734 TDSCQGDSGGPLVCFEKDKYILQGVTSWGLG-CARPNKPGVYVRVSRFVTWIE 785 >1VR1-H nrPDB Length = 261 Score = 106 bits (265), Expect = 9e-24, Method: Compositional matrix adjust. Identities = 78/259 (30%), Positives = 115/259 (44%), Gaps = 39/259 (15%) Query: 31 IINGEDCSPHSQPWQAALVMENE------LFCSGVLVHPQWVLSAAHCF----------Q 74 I+ G D PWQ L ++ C L+ +WVL+AAHC + Sbjct: 1 IVEGSDAEIGMSPWQVMLFAKHRRSPGERFLCGASLISDRWVLTAAHCLLYPPWDKNFTE 60 Query: 75 NSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYN-RPLLANDLMLIKLDESVSESDTIR 133 N + +G HS + ++ HP YN R L D+ L+KL + V+ SD I Sbjct: 61 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIH 120 Query: 134 SI-----SIASQCPTAGNSCLVSGWGLLAN------GR-MPTVLQCVNVSVVSEEVCSKL 181 + A+ AG V+GWG L G+ P+VLQ VN+ +V VC Sbjct: 121 PVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDS 180 Query: 182 YDPLYHPSMFCAGGGHDQ---KDSCNGDSGGPLICNG------YLQGLVSFGKAPCGQVG 232 +MFCA D+ D+C GDSGGP + Y G+VS+G+ C + G Sbjct: 181 TRIRITDNMFCAYYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEG-CDRDG 239 Query: 233 VPGVYTNLCKFTEWIEKTV 251 G YT++ + +WI+K + Sbjct: 240 KYGFYTHVFRLKKWIQKVI 258 >4Z6A-H nrPDB Length = 249 Score = 106 bits (264), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 77/240 (32%), Positives = 112/240 (46%), Gaps = 19/240 (7%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQ-----NSYTIGLGLHS 85 I+ G+ C PWQ L++ C G L++ WV+SAAHCF + LG H Sbjct: 1 IVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLGEHD 60 Query: 86 LEADQEPGSQMVEASLSVRHPEYNRPLLAN-DLMLIKLDESVSESDTIRSI-----SIAS 139 L + G + V P P N D+ L++L + V +D + + + + Sbjct: 61 LS--EHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSE 118 Query: 140 QCPTAGNSCLVSGWG-LLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHD 198 + LVSGWG LL G L +NV + + C Y MFCAG Sbjct: 119 RTLAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQDCEASYPGKITEYMFCAGYSDG 178 Query: 199 QKDSCNGDSGGPLICN----GYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 KDSC GDSGGP + YL G+VS+G+ C VG GVYT + ++ EW++K +++ Sbjct: 179 SKDSCKGDSGGPHATHYRGTWYLTGIVSWGQG-CATVGHFGVYTRVSQYIEWLQKLMRSE 237 >2XRC-A nrPDB Length = 565 Score = 105 bits (263), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 73/235 (31%), Positives = 112/235 (47%), Gaps = 19/235 (8%) Query: 29 SQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEA 88 +I+ G+ PWQ A+ + + C G+ + W+L+AAHC + S T + + Sbjct: 320 KRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVV 379 Query: 89 DQ-EPGSQMVEASLSVR---HPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCP-- 142 D P + + R H YN ND+ LI++ + ++ D SI + P Sbjct: 380 DWIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWS 439 Query: 143 ----TAGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLY-DPLYHPSMFCAGGGH 197 ++C+VSGWG + LQ V ++S CSK Y + Y M CAG Sbjct: 440 PYLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISN--CSKFYGNRFYEKEMECAGTYD 497 Query: 198 DQKDSCNGDSGGPLICNG-----YLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWI 247 D+C GDSGGPL+C Y+ G+VS+G+ CG+ PGVYT + + +WI Sbjct: 498 GSIDACKGDSGGPLVCMDANNVTYVWGVVSWGEN-CGKPEFPGVYTKVANYFDWI 551 >4DJZ-B nrPDB Length = 251 Score = 105 bits (263), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 76/250 (30%), Positives = 109/250 (43%), Gaps = 32/250 (12%) Query: 31 IINGEDCSPHSQPWQAALVMEN-ELFCSGVLVHPQWVLSAAHCFQNS------------- 76 I NG + PW A L N + FC G L+ W+++AAHC S Sbjct: 1 IFNGRPAQKGTTPWIAMLSHLNGQPFCGGSLLGSSWIVTAAHCLHQSLDPKDPTLRDSDL 60 Query: 77 -----YTIGLGLH-SLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESD 130 + I LG H L +D+ Q + + HP+Y+ ND+ L++L ES + Sbjct: 61 LSPSDFKIILGKHWRLRSDEN--EQHLGVKHTTLHPQYDPNTFENDVALVELLESPVLNA 118 Query: 131 TIRSISIASQCPTAGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHP-- 188 + I + G +VSGWG R P L + + +V C K Y PL Sbjct: 119 FVMPICLPEGPQQEGAMVIVSGWGKQFLQRFPETLMEIEIPIVDHSTCQKAYAPLKKKVT 178 Query: 189 -SMFCAGGGHDQKDSCNGDSGGPLIC------NGYLQGLVSFGKAPCGQVGVPGVYTNLC 241 M CAG KD+C GDSGGP++ YL G VS+G CG+ GVY+ + Sbjct: 179 RDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGDD-CGKKDRYGVYSYIH 237 Query: 242 KFTEWIEKTV 251 +WI++ Sbjct: 238 HNKDWIQRVT 247 >6AOD-C nrPDB Length = 245 Score = 105 bits (261), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 73/239 (30%), Positives = 115/239 (48%), Gaps = 18/239 (7%) Query: 31 IINGEDCSPHSQPWQAALVMEN---ELFCSGVLVHPQWVLSAAHCFQNSYTIG-LGLHS- 85 I+ G PWQ L + C G ++ QW+L+AAHCF + L ++S Sbjct: 1 IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSG 60 Query: 86 --LEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCP- 142 +++ + + + H +Y D+ L+KL+ +V +D+ R IS+ S+ Sbjct: 61 ILQQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVQYTDSQRPISLPSKGDR 120 Query: 143 -TAGNSCLVSGWGLLA-NGRMPTVLQCVNVSVVSEEVCSKLYD--PLYHPSMFCAGGGHD 198 C V+GWG ++ LQ + +V+ E C K Y + H M CAG Sbjct: 121 NVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITH-KMICAGYREG 179 Query: 199 QKDSCNGDSGGPLICNG----YLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQA 253 KD+C GD+GGPL C +L G+ S+G+ C Q PGVYTN+ ++ +WI + QA Sbjct: 180 GKDACKGDAGGPLSCKHNEVWHLVGITSWGEG-CAQRERPGVYTNVVEYVDWILEKTQA 237 >4BXW-A nrPDB Length = 423 Score = 103 bits (257), Expect = 7e-23, Method: Compositional matrix adjust. Identities = 71/243 (29%), Positives = 117/243 (48%), Gaps = 21/243 (8%) Query: 30 QIINGEDCSPHSQPWQAALVMENE-LFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEA 88 +I+NG DC PWQAALV E E +FC G ++ P +VL+AAHC + TI + + ++ Sbjct: 169 RIVNGMDCKLGECPWQAALVDEKEGVFCGGTILSPIYVLTAAHCINETETISVVVGEIDK 228 Query: 89 DQEPGSQMVEASLSVRHPEYNRPLLAN---------DLMLIKLDESVSESDTI-----RS 134 + ++ H ++ P A D+ +I++ + S+ + + Sbjct: 229 SRIETGPLLSVDKIYVHKKFVPPQKAYKFDLAAYDYDIAIIQMKTPIQFSENVVPACLPT 288 Query: 135 ISIASQCPTAGNSCLVSGWG-LLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCA 193 A+Q + +VSG+G ++ G L+ + V V C + P+MFCA Sbjct: 289 ADFANQVLMKQDFGIVSGFGRIVEKGPKSKTLKVLKVPYVDRHTCMVSSETPITPNMFCA 348 Query: 194 GGGHDQKDSCNGDSGGPLIC----NGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEK 249 G +D+C GDSGGP ++ G+VS G+ C + G G YT L KF WI++ Sbjct: 349 GYDTLPRDACQGDSGGPHTTVYRDTHFITGIVSSGEG-CARNGKYGNYTKLSKFIPWIKR 407 Query: 250 TVQ 252 ++ Sbjct: 408 IMR 410 >3RP2-A nrPDB Length = 224 Score = 103 bits (257), Expect = 7e-23, Method: Compositional matrix adjust. Identities = 70/231 (30%), Positives = 110/231 (47%), Gaps = 18/231 (7%) Query: 31 IINGEDCSPHSQPWQAALVMENE----LFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSL 86 II G + PHS+P+ A L + E + C G L+ Q+VL+AAHC T+ LG H + Sbjct: 1 IIGGVESIPHSRPYMAHLDIVTEKGLRVICGGFLISRQFVLTAAHCKGREITVILGAHDV 60 Query: 87 EADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCP--TA 144 +E Q ++ + H YN +D+ML+KL++ V + + + + S Sbjct: 61 R-KRESTQQKIKVEKQIIHESYNSVPNLHDIMLLKLEKKVELTPAVNVVPLPSPSDFIHP 119 Query: 145 GNSCLVSGWGLLANGRMPT--VLQCVNVSVVSEEVCSKLYDPLYHPSMF--CAGGGHDQK 200 G C +GWG R PT L+ V + ++ E+ C D Y+ F C G + Sbjct: 120 GAMCWAAGWGK-TGVRDPTSYTLREVELRIMDEKAC---VDYRYYEYKFQVCVGSPTTLR 175 Query: 201 DSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 251 + GDSGGPL+C G G+VS+G P ++T + + WI + Sbjct: 176 AAFMGDSGGPLLCAGVAHGIVSYGHPDAKP---PAIFTRVSTYVPWINAVI 223 >2OQ5-A nrPDB Length = 232 Score = 102 bits (254), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 66/227 (29%), Positives = 103/227 (45%), Gaps = 11/227 (4%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 I+ G + PWQA+L + C L++ W++SAAHCF S Sbjct: 1 IVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTYKNPARWTASFGVTI 60 Query: 91 EPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISI--ASQCPTAGNSC 148 +P + H +Y P D+ L +L V ++ + + + AS G+ Sbjct: 61 KPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASYEFQPGDVM 120 Query: 149 LVSGWGLLAN-GRMPTVLQCVNVSVVSEEVCS--KLYDPLYHPSMFCAGGGHDQKDSCNG 205 V+G+G L N G L+ V+++ C+ + Y+ P M CAG + D+C G Sbjct: 121 FVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITPRMLCAGSLEGKTDACQG 180 Query: 206 DSGGPLICNG-----YLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWI 247 DSGGPL+ + YL G+VS+G C + PGVYT + +WI Sbjct: 181 DSGGPLVSSDARDIWYLAGIVSWGDE-CAKPNKPGVYTRVTALRDWI 226 >2F83-A nrPDB Length = 625 Score = 102 bits (254), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 73/235 (31%), Positives = 111/235 (47%), Gaps = 34/235 (14%) Query: 43 PWQAALVMEN---ELFCSGVLVHPQWVLSAAHCFQ--------NSYTIGLGLHSLEADQE 91 PWQ L + C G ++ QW+L+AAHCF Y+ L ++ D Sbjct: 400 PWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSGILNQSEIKED-- 457 Query: 92 PGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNS---- 147 + + H +Y D+ L+KL+ +V+ +D+ R I + P+ G+ Sbjct: 458 --TSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPICL----PSKGDRNVIY 511 Query: 148 --CLVSGWGLLA-NGRMPTVLQCVNVSVVSEEVCSKLYD--PLYHPSMFCAGGGHDQKDS 202 C V+GWG ++ LQ + +V+ E C K Y + H M CAG KD+ Sbjct: 512 TDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITH-KMICAGYREGGKDA 570 Query: 203 CNGDSGGPLICNG----YLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQA 253 C GDSGGPL C +L G+ S+G+ C Q PGVYTN+ ++ +WI + QA Sbjct: 571 CKGDSGGPLSCKHNEVWHLVGITSWGEG-CAQRERPGVYTNVVEYVDWILEKTQA 624 >4LK4-A nrPDB Length = 357 Score = 100 bits (249), Expect = 6e-22, Method: Compositional matrix adjust. Identities = 73/243 (30%), Positives = 124/243 (51%), Gaps = 30/243 (12%) Query: 29 SQIINGEDCSPHSQPWQAALVMENE-----LFCSGVLVHPQWVLSAAHCF--QNSYTIGL 81 S+IING + + P ALV FC G + ++VL+AAHCF +++ ++ + Sbjct: 9 SRIINGSNANSAEWPSIVALVKRGADAYQGQFCGGSFLGGRYVLTAAHCFDSRSAASVDV 68 Query: 82 GLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQC 141 + + + + + + A RH Y+ L ND+ +++L +++ ++ +I++A Sbjct: 69 IIGAYDLNNSSQGERIAAQKIYRHLSYSPSNLLNDIAIVEL----AQTSSLPAITLAGPA 124 Query: 142 PTAGNSCL----VSGWGLLANGRMPT---VLQCVNVSVVSEEVCSKLY------DPLYHP 188 L V+GWG+ + P +LQ V+V +VS+ +C + DP + Sbjct: 125 TRTSLPALTPLTVAGWGITVQSKPPQFTPILQEVDVDLVSQSLCQIVMQHGISSDP--NS 182 Query: 189 SMFCAGGGHDQKDSCNGDSGGPLICN-GYLQ-GLVSFGKAPCGQVGVPGVYTNLCKFTEW 246 + FCA KDSC GD+GGP++ G Q G+VS+G C + G GVYTN+ F +W Sbjct: 183 TNFCAA--RLTKDSCQGDAGGPIVVKTGREQLGIVSWGDEQCAKTGTYGVYTNVSYFRDW 240 Query: 247 IEK 249 I K Sbjct: 241 ITK 243 >2B9L-A nrPDB Length = 394 Score = 98.6 bits (244), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 72/245 (29%), Positives = 109/245 (44%), Gaps = 35/245 (14%) Query: 43 PWQAALVM--------ENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEA------ 88 PW A++ E +L C G L+ P VL+ AHC NSY L + A Sbjct: 143 PWMVAVLKANVIPGSGEEQLVCGGSLIAPSVVLTGAHCV-NSYQSNLDAIKIRAGEWDTL 201 Query: 89 --DQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGN 146 + Q + + H +N + ND+ L+ LD + ++D I +I + Q + Sbjct: 202 TEKERLPYQERKIRQVIIHSNFNPKTVVNDVALLLLDRPLVQADNIGTICLPQQSQIFDS 261 Query: 147 S-CLVSGWGLLANG---RMPTVLQCVNVSVVSEEVC------SKLYDPLYHPSMFCAGGG 196 + C SGWG G R +L+ + + V + C ++L F GG Sbjct: 262 TECFASGWGKKEFGSRHRYSNILKKIQLPTVDRDKCQADLRNTRLGLKFVLDQTFVCAGG 321 Query: 197 HDQKDSCNGDSGGPLIC------NGYLQ-GLVSFGKAPCGQVGVPGVYTNLCKFTEWIEK 249 KD+C GD G PL C + Y+Q G+V++G CG VPGVY N+ F WI++ Sbjct: 322 EQGKDTCTGDGGSPLFCPDPRNPSRYMQMGIVAWGIG-CGDENVPGVYANVAHFRNWIDQ 380 Query: 250 TVQAS 254 +QA Sbjct: 381 EMQAK 385 >5XW8-A nrPDB Length = 133 Score = 96.7 bits (239), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 46/125 (36%), Positives = 74/125 (59%), Gaps = 2/125 (1%) Query: 30 QIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEAD 89 +I+ G C+ +S P+Q +L FC G L++ QWV+SAAHC+++ + LG H+++ Sbjct: 8 KIVGGYTCAANSIPYQVSL-NSGSHFCGGSLINSQWVVSAAHCYKSRIQVRLGEHNIDV- 65 Query: 90 QEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCL 149 E Q + A+ + HP +N L ND+MLIKL + + + ++S+ C AG CL Sbjct: 66 LEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRSCAAAGTECL 125 Query: 150 VSGWG 154 +SGWG Sbjct: 126 ISGWG 130 >4XDE-A nrPDB Length = 257 Score = 96.7 bits (239), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 75/232 (32%), Positives = 109/232 (46%), Gaps = 26/232 (11%) Query: 41 SQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQN-----SYTIGLGLHSLEADQEPGSQ 95 + P+ AAL + FC+G L+ P WVL+AAHC Q+ T+ LG EP Sbjct: 13 AHPYIAALYWGHS-FCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVLGQERRNHSCEPCQT 71 Query: 96 MVEASLSVRHPEYNRPLLANDLMLIKLDESVSES-----DTIRSISIASQC--PTAGNSC 148 + S + H ++ +DL L++L E S ++ +S+ S P+ C Sbjct: 72 LAVRSYRL-HEAFSPVSYQHDLALLRLQEDADGSCALLSPYVQPVSLPSGAARPSETTLC 130 Query: 149 LVSGWGLLANG--RMPTVLQCVNVSVVSEEVCS--KLYDPLYHPSMFCAGGGHDQKDSCN 204 V+GWG G + LQ V +S E CS ++ P M CAG D+C Sbjct: 131 QVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGSSILPGMLCAGFLEGGTDACQ 190 Query: 205 GDSGGPLICNGY-------LQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEK 249 GDSGGPL+C LQG++S+G CG PGVYT++ + WI + Sbjct: 191 GDSGGPLVCEDQAAERRLTLQGIISWGSG-CGDRNKPGVYTDVAYYLAWIRE 241 >5KWM-A nrPDB Length = 230 Score = 96.3 bits (238), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 68/227 (29%), Positives = 104/227 (45%), Gaps = 7/227 (3%) Query: 31 IINGEDCSPHSQPWQAALVM-ENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEAD 89 I+ GED + P+ ALV + + FC G L P V++AAHC S + + S Sbjct: 1 IVGGEDANVQDHPFTVALVTPDGQQFCGGTLAAPNKVVTAAHCTVGSQPADINVVSGRTV 60 Query: 90 QEPGSQMVEASLSV-RHPEYNRPLLANDLMLIKLDESVSESD-TIRSISIASQCPTAGNS 147 V +V HPEY D+ ++ L+ V E+ + A P + Sbjct: 61 MSSNEGTVSKVTNVWVHPEYQDAAKGFDVSVLTLEAPVKEAPIELAKADDAGYAPDTAAT 120 Query: 148 CLVSGWGLLANG-RMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGD 206 L GWG + G + LQ V V S++ C + Y +M CAG D+C GD Sbjct: 121 IL--GWGNTSEGGQQADHLQKATVPVNSDDTCKQAYGEYTPDAMVCAGVPEGGVDTCQGD 178 Query: 207 SGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQA 253 SGGP++ N L G+ S+G+ C + G PGVY + + + + + + A Sbjct: 179 SGGPMVVNNKLIGVTSWGEG-CARPGKPGVYARVGAYYDVLMEQINA 224 >1FIZ-A nrPDB Length = 263 Score = 95.5 bits (236), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 70/249 (28%), Positives = 110/249 (44%), Gaps = 29/249 (11%) Query: 31 IINGEDCSPHSQPWQAALVM----ENELF--CSGVLVHPQWVLSAAHCFQNSYTIGLGLH 84 ++ G P + PW +L + N + C G+L++ WVL+AAHCF+N + Sbjct: 1 VVGGMSAEPGAWPWMVSLQIFMYHNNRRYHTCGGILLNSHWVLTAAHCFKNKKKVTDWRL 60 Query: 85 SLEADQ---------EPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRS- 134 A++ +P Q + H +Y L ND+ LIK+ V I Sbjct: 61 IFGANEVVWGSNKPVKPPLQERFVEEIIIHEKYVSGLEINDIALIKITPPVPCGPFIGPG 120 Query: 135 --ISIASQCPTAGNSCLVSGWGLLANG--RMPTVLQCVNVSVVSEEVC--SKLYDPLYHP 188 + P A +C V+GWG L R LQ V+++ E+C ++ Y+ Sbjct: 121 CLPQFKAGPPRAPQTCWVTGWGYLKEKGPRTSPTLQEARVALIDLELCNSTRWYNGRIRS 180 Query: 189 SMFCAGGGHDQKDSCNGDSGGPLICNGYLQ------GLVSFGKAPCGQVGVPGVYTNLCK 242 + CAG + D+C GDSGGPL+C + G+ S+G C + PGVYT+ Sbjct: 181 TNVCAGYPRGKIDTCQGDSGGPLMCRDRAENTFVVVGITSWGVG-CARAKRPGVYTSTWP 239 Query: 243 FTEWIEKTV 251 + WI + Sbjct: 240 YLNWIASKI 248 >1A5I-A nrPDB Length = 265 Score = 95.1 bits (235), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 73/246 (29%), Positives = 114/246 (46%), Gaps = 39/246 (15%) Query: 41 SQPWQAALVMENE------LFCSGVLVHPQWVLSAAHCFQNSY-------TIGLGLHSLE 87 S PWQAA+ +N C G+L+ WVL+AAHCFQ SY +G Sbjct: 24 SHPWQAAIFAQNRRSSGERFLCGGILISSCWVLTAAHCFQESYLPDQLKVVLGRTYRVKP 83 Query: 88 ADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLD----ESVSESDTIRSISIAS---Q 140 ++E Q + + H E++ ND+ L++L + ESD++R+I + Q Sbjct: 84 GEEE---QTFKVKKYIVHKEFDDDTYNNDIALLQLKSDSPQCAQESDSVRAICLPEANLQ 140 Query: 141 CPTAGNSCLVSGWGLLANGR--MPTVLQCVNVSVVSEEVCSK--LYDPLYHPSMFCAGGG 196 P C +SG+G + L+ +V + C+ L++ +M CAG Sbjct: 141 LPDW-TECELSGYGKHKSSSPFYSEQLKEGHVRLYPSSRCAPKFLFNKTVTNNMLCAGDT 199 Query: 197 H------DQKDSCNGDSGGPLIC----NGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEW 246 + D+C GDSGGPL+C + L G++S+G CG+ VPGVYT + + W Sbjct: 200 RSGEIYPNVHDACQGDSGGPLVCMNDNHMTLLGIISWGVG-CGEKDVPGVYTKVTNYLGW 258 Query: 247 IEKTVQ 252 I + Sbjct: 259 IRDNMH 264 >1ZJK-A nrPDB Length = 403 Score = 95.1 bits (235), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 67/242 (27%), Positives = 109/242 (45%), Gaps = 22/242 (9%) Query: 30 QIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCF----QNSYTIGLGLHS 85 QI G+ P PWQ ++ +G L++ WVL+AAH ++ + + + + Sbjct: 161 QIYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNWVLTAAHAVYEQKHDASALDIRMGT 218 Query: 86 LEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISI----ASQC 141 L+ +Q ++ + + ND+ LIKL+ V + I I + A Sbjct: 219 LKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPICLPRKEAESF 278 Query: 142 PTAGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHP------SMFCAGG 195 + SGWGL G + L V++ +V + C+ Y+ +P +M CAG Sbjct: 279 MRTDDIGTASGWGLTQRGFLARNLMYVDIPIVDHQKCTAAYEKPPYPRGSVTANMLCAGL 338 Query: 196 GHDQKDSCNGDSGGPLIC------NGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEK 249 KDSC GDSGG L+ ++ G+VS+G CG+ G GVYT + + WIE Sbjct: 339 ESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVYTKVINYIPWIEN 398 Query: 250 TV 251 + Sbjct: 399 II 400 >1Q3X-A nrPDB Length = 328 Score = 94.4 bits (233), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 66/242 (27%), Positives = 109/242 (45%), Gaps = 22/242 (9%) Query: 30 QIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCF----QNSYTIGLGLHS 85 +I G+ P PWQ ++ +G L++ WVL+AAH ++ + + + + Sbjct: 86 RIYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNWVLTAAHAVYEQKHDASALDIRMGT 143 Query: 86 LEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISI----ASQC 141 L+ +Q ++ + + ND+ LIKL+ V + I I + A Sbjct: 144 LKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPICLPRKEAESF 203 Query: 142 PTAGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHP------SMFCAGG 195 + SGWGL G + L V++ +V + C+ Y+ +P +M CAG Sbjct: 204 MRTDDIGTASGWGLTQRGFLARNLMYVDIPIVDHQKCTAAYEKPPYPRGSVTANMLCAGL 263 Query: 196 GHDQKDSCNGDSGGPLIC------NGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEK 249 KDSC GDSGG L+ ++ G+VS+G CG+ G GVYT + + WIE Sbjct: 264 ESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVYTKVINYIPWIEN 323 Query: 250 TV 251 + Sbjct: 324 II 325 >4FXG-H nrPDB Length = 242 Score = 93.6 bits (231), Expect = 7e-20, Method: Compositional matrix adjust. Identities = 65/241 (26%), Positives = 108/241 (44%), Gaps = 22/241 (9%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCF----QNSYTIGLGLHSL 86 I G+ P PWQ ++ +G L++ WVL+AAH ++ + + + +L Sbjct: 1 IYGGQKAKPGDFPWQVLILGGTT--AAGALLYDNWVLTAAHAVYEQKHDASALDIRMGTL 58 Query: 87 EADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISI----ASQCP 142 + +Q ++ + + ND+ LIKL+ V + I I + A Sbjct: 59 KRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPICLPRKEAESFM 118 Query: 143 TAGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHP------SMFCAGGG 196 + SGWGL G + L V++ +V + C+ Y+ +P +M CAG Sbjct: 119 RTDDIGTASGWGLTQRGFLARNLMYVDIPIVDHQKCTAAYEKPPYPRGSVTANMLCAGLE 178 Query: 197 HDQKDSCNGDSGGPLIC------NGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKT 250 KDSC GD+GG L+ ++ G+VS+G CG+ G GVYT + + WIE Sbjct: 179 SGGKDSCRGDAGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVYTKVINYIPWIENI 238 Query: 251 V 251 + Sbjct: 239 I 239 >4IW4-E nrPDB Length = 279 Score = 93.2 bits (230), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 78/264 (29%), Positives = 119/264 (45%), Gaps = 49/264 (18%) Query: 31 IINGEDCSPHSQPWQAALVMEN-------ELFCSGVLVHPQWVLSAAHCFQNSY------ 77 II G + P PWQA +V+E+ + F SG L+ W+L+AAH ++ Sbjct: 1 IIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVI 60 Query: 78 -------TIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESD 130 T+ LGLH + + G+ A+ V HP++N +D+ L++L E V Sbjct: 61 PVSKEHVTVYLGLHDVR--DKSGAVNSSAARVVLHPDFNIQNYNHDIALVQLQEPVPLGP 118 Query: 131 TIRSI---SIASQCPTAGNSCLVSGWGL----------LANGR--MPTVLQCVNVSVVSE 175 + + + + P LV+GWG+ +++G + VLQ V + VV Sbjct: 119 HVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPH 178 Query: 176 EVCSKLYDPL-----YHPSMFCAGGGHDQKDSCNGDSGGPLICNGYL------QGLVSF- 223 C Y+ +MFCAG KD+C GDSGG + L QGLVS+ Sbjct: 179 AECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGGAFVIFDDLSQRWVVQGLVSWG 238 Query: 224 GKAPCGQVGVPGVYTNLCKFTEWI 247 G CG V GVYT + + +W+ Sbjct: 239 GPEECGSKQVYGVYTKVSNYVDWV 262 >1FIW-A nrPDB Length = 290 Score = 92.4 bits (228), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 71/249 (28%), Positives = 114/249 (45%), Gaps = 29/249 (11%) Query: 31 IINGEDCSPHSQPWQAALVM----ENELF--CSGVLVHPQWVLSAAHCFQ-----NSYTI 79 II G+D + + PW +L + N + C G L++ QW+L+AAHCF+ + + Sbjct: 1 IIGGQDAAHGAWPWMVSLQIFTYHNNRRYHVCGGSLLNSQWLLTAAHCFRIKKKVTDWRL 60 Query: 80 GLGLHSLE----ADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRS- 134 G +E +P Q + H +Y+ AND+ L+K+ V+ I Sbjct: 61 IFGAKEVEWGTNKPVKPPLQERYVEKIIIHEKYSASSEANDIALMKITPPVTCGHFIGPG 120 Query: 135 --ISIASQCPTAGNSCLVSGWGLLANG--RMPTVLQCVNVSVVSEEVC--SKLYDPLYHP 188 + P +C V+GWG L R +LQ V ++ +C ++ Y+ Sbjct: 121 CLPQFRAGPPRVPQTCWVAGWGFLQENARRTSPMLQEARVDLIDLGLCNSTRWYNGRIRS 180 Query: 189 SMFCAGGGHDQKDSCNGDSGGPLIC-----NGY-LQGLVSFGKAPCGQVGVPGVYTNLCK 242 + CAG + D+C GDSGGPL+C N Y + G+ S+G C + PGVYT+ Sbjct: 181 TNVCAGYPEGKIDTCQGDSGGPLMCKDSAENSYVVVGITSWGVG-CARAKRPGVYTSTWS 239 Query: 243 FTEWIEKTV 251 + WI + Sbjct: 240 YLNWIASKI 248 >1BDA-A nrPDB Length = 265 Score = 91.7 bits (226), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 71/246 (28%), Positives = 112/246 (45%), Gaps = 39/246 (15%) Query: 41 SQPWQAALVMENE------LFCSGVLVHPQWVLSAAHCFQNSY-------TIGLGLHSLE 87 S PWQAA+ ++ C G+L+ W+LSAAHCFQ + +G + Sbjct: 24 SHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQERFPPHHLTVILGRTYRVVP 83 Query: 88 ADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVS----ESDTIRSISIAS---Q 140 ++E Q E + H E++ ND+ L++L S ES +R++ + Q Sbjct: 84 GEEE---QKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRTVCLPPADLQ 140 Query: 141 CPTAGNSCLVSGWGL--LANGRMPTVLQCVNVSVVSEEVCS--KLYDPLYHPSMFCAGGG 196 P C +SG+G + L+ +V + C+ L + +M CAG Sbjct: 141 LPD-WTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCTSQHLLNRTVTDNMLCAGDT 199 Query: 197 H------DQKDSCNGDSGGPLIC----NGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEW 246 + D+C GDSGGPL+C L G++S+G CGQ VPGVYT + + +W Sbjct: 200 RSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWGLG-CGQKDVPGVYTKVTNYLDW 258 Query: 247 IEKTVQ 252 I ++ Sbjct: 259 IRDNMR 264 >1PQ7-A nrPDB Length = 224 Score = 91.3 bits (225), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 73/226 (32%), Positives = 105/226 (46%), Gaps = 13/226 (5%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 I+ G S P+ ++ +C G L++ VL+AAHC G + + + Sbjct: 1 IVGGTSASAGDFPFIVSISRNGGPWCGGSLLNANTVLTAAHCVSGYAQSGFQIRAGSLSR 60 Query: 91 EPGSQMVEASLS-VR-HPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQC--PTAGN 146 G + +SLS VR HP Y+ NDL ++KL S+ I +A+ P AG+ Sbjct: 61 TSGG--ITSSLSSVRVHPSYSGN--NNDLAILKLSTSIPSGGNIGYARLAASGSDPVAGS 116 Query: 147 SCLVSGWGLLANG--RMPTVLQCVNVSVVSEEVCSKLY-DPLYHPSMFCAGGGHDQKDSC 203 S V+GWG + G P L V V +VS C Y MFCAG KDSC Sbjct: 117 SATVAGWGATSEGGSSTPVNLLKVTVPIVSRATCRAQYGTSAITNQMFCAGVSSGGKDSC 176 Query: 204 NGDSGGPLI-CNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIE 248 GDSGGP++ + L G VS+G C + GVY ++ +I+ Sbjct: 177 QGDSGGPIVDSSNTLIGAVSWGNG-CARPNYSGVYASVGALRSFID 221 >5UBM-A nrPDB Length = 252 Score = 90.5 bits (223), Expect = 7e-19, Method: Compositional matrix adjust. Identities = 74/254 (29%), Positives = 113/254 (44%), Gaps = 41/254 (16%) Query: 30 QIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSY--TIGLGLHSLE 87 +II G D + PWQ V + + G L++ WVL+AAH + + T+ +G S++ Sbjct: 1 RIIGGSDADIKNFPWQ---VFFDNPWAGGALINEYWVLTAAHVVEGNREPTMYVGSTSVQ 57 Query: 88 ADQEPGSQMVEASLSVRHPEYN-------RPLLANDLMLIKLDESVSESDTIRSISIASQ 140 + S+M+ HP + R ND+ L++L + V T+ I + Sbjct: 58 TSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLPGT 117 Query: 141 CPT----AGNSCLVSGWGL---------LANGRMPT--VLQCVNVSVVSEEVCSKLYDPL 185 G+ L+SGWG L R+P + +C V V ++ Y + Sbjct: 118 SSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKVEKPTADAEAY--V 175 Query: 186 YHPSMFCAGGGHDQKDSCNGDSGGPLICNG-------YLQGLVSFGKAPCGQVGVPGVYT 238 + P+M CAGG DSC GDSGG Y GLVS+G Q G G+YT Sbjct: 176 FTPNMICAGG-EKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGP----QCGTYGLYT 230 Query: 239 NLCKFTEWIEKTVQ 252 + + +WI KT+Q Sbjct: 231 RVKNYVDWIMKTMQ 244 >4KKD-A nrPDB Length = 433 Score = 89.7 bits (221), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 77/265 (29%), Positives = 119/265 (44%), Gaps = 49/265 (18%) Query: 30 QIINGEDCSPHSQPWQAALVMEN-------ELFCSGVLVHPQWVLSAAHCFQNSY----- 77 +II G + P PWQA +V+E+ + F SG L+ W+L+AAH ++ Sbjct: 154 RIIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTV 213 Query: 78 --------TIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSES 129 T+ LGLH + + G+ A+ V HP++N +D+ L++L E V Sbjct: 214 IPVSKEHVTVYLGLHDVR--DKSGAVNSSAARVVLHPDFNIQNYNHDIALVQLQEPVPLG 271 Query: 130 DTIRSI---SIASQCPTAGNSCLVSGWGL----------LANGR--MPTVLQCVNVSVVS 174 + + + + P LV+GWG+ +++G + VLQ V + VV Sbjct: 272 PHVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVP 331 Query: 175 EEVCSKLYDPL-----YHPSMFCAGGGHDQKDSCNGDSGGPLICNGYL------QGLVSF 223 C Y+ +MFCAG KD+C GDSG + L QGLVS+ Sbjct: 332 HAECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGEAFVIFDDLSQRWVVQGLVSW 391 Query: 224 -GKAPCGQVGVPGVYTNLCKFTEWI 247 G CG V GVYT + + +W+ Sbjct: 392 GGPEECGSKQVYGVYTKVSNYVDWV 416 >1ELV-A nrPDB Length = 333 Score = 89.4 bits (220), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 74/256 (28%), Positives = 114/256 (44%), Gaps = 41/256 (16%) Query: 30 QIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSY--TIGLGLHSLE 87 +II G D + PWQ V + + G L++ WVL+AAH + + T+ +G S++ Sbjct: 82 RIIGGSDADIKNFPWQ---VFFDNPWAGGALINEYWVLTAAHVVEGNREPTMYVGSTSVQ 138 Query: 88 ADQEPGSQMVEASLSVRHPEYN-------RPLLANDLMLIKLDESVSESDTIRSISIASQ 140 + S+M+ HP + R ND+ L++L + V T+ I + Sbjct: 139 TSRLAKSKMLTPEHVFIHPGWKLLAVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLPGT 198 Query: 141 CPT----AGNSCLVSGWGL---------LANGRMPT--VLQCVNVSVVSEEVCSKLYDPL 185 G+ L+SGWG L R+P + +C V V ++ Y + Sbjct: 199 SSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKVEKPTADAEAY--V 256 Query: 186 YHPSMFCAGGGHDQKDSCNGDSGGPLICNG-------YLQGLVSFGKAPCGQVGVPGVYT 238 + P+M CAGG DSC GDSGG Y GLVS+G Q G G+YT Sbjct: 257 FTPNMICAGG-EKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGP----QCGTYGLYT 311 Query: 239 NLCKFTEWIEKTVQAS 254 + + +WI KT+Q + Sbjct: 312 RVKNYVDWIMKTMQEN 327 >1ELT-A nrPDB Length = 236 Score = 87.8 bits (216), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 68/236 (28%), Positives = 114/236 (48%), Gaps = 21/236 (8%) Query: 31 IINGEDCSPHSQPWQAALVMEN----ELFCSGVLVHPQWVLSAAHCFQNSYT--IGLGLH 84 ++ G P+S PWQ +L ++ C G L+ WV++AAHC ++ T + LG H Sbjct: 1 VVGGRVAQPNSWPWQISLQYKSGSSYYHTCGGSLIRQGWVMTAAHCVDSARTWRVVLGEH 60 Query: 85 SLEADQEPGSQMVEASLSVRHPEYNRPLLAN--DLMLIKLDESVSESDTIRSISI--ASQ 140 +L + E Q++ + H +N +A D+ L++L+ S + ++ ++ ++Q Sbjct: 61 NLNTN-EGKEQIMTVNSVFIHSGWNSDDVAGGYDIALLRLNTQASLNSAVQLAALPPSNQ 119 Query: 141 CPTAGNSCLVSGWGLLANGR-MPTVLQCVNVSVVSEEVCSK--LYDPLYHPSMFCAGGGH 197 N C ++GWG + G + L+ + V CS + +M CAGGG Sbjct: 120 ILPNNNPCYITGWGKTSTGGPLSDSLKQAWLPSVDHATCSSSGWWGSTVKTTMVCAGGGA 179 Query: 198 DQKDSCNGDSGGPLIC--NG--YLQGLVSF-GKAPCGQVGVPGVYTNLCKFTEWIE 248 + CNGDSGGPL C NG Y+ G+ SF + C P V+T + + W+ Sbjct: 180 N--SGCNGDSGGPLNCQVNGSYYVHGVTSFVSSSGCNASKKPTVFTRVSAYISWMN 233 >2V35-A nrPDB Length = 240 Score = 87.4 bits (215), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 73/244 (29%), Positives = 119/244 (48%), Gaps = 24/244 (9%) Query: 31 IINGEDCSPHSQPWQAALVMEN----ELFCSGVLVHPQWVLSAAHCFQN--SYTIGLGLH 84 ++ G + +S P Q +L + C G L+ WV++AAHC ++ + +G H Sbjct: 1 VVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDRELTFRVVVGEH 60 Query: 85 SLEADQEPGS-QMVEASLSVRHPEYNRPLLAN--DLMLIKLDESVSESDTIRSISIASQC 141 +L +Q G+ Q V V HP +N +A D+ L++L +SV+ + ++ + + + Sbjct: 61 NL--NQNDGTEQYVGVQKIVVHPYWNTDDVAAGYDIALLRLAQSVTLNSYVQ-LGVLPRA 117 Query: 142 PT--AGNS-CLVSGWGLL-ANGRMPTVLQCVNVSVVSEEVC--SKLYDPLYHPSMFCAGG 195 T A NS C ++GWGL NG++ LQ + V +C S + SM CA G Sbjct: 118 GTILANNSPCYITGWGLTRTNGQLAQTLQQAYLPTVDYAICSSSSYWGSTVKNSMVCA-G 176 Query: 196 GHDQKDSCNGDSGGPLIC--NGY--LQGLVSF-GKAPCGQVGVPGVYTNLCKFTEWIEKT 250 G + C GDSGGPL C NG + G+ SF + C P V+T + + WI Sbjct: 177 GDGVRSGCQGDSGGPLHCLVNGQYAVHGVTSFVSRLGCNVTRKPTVFTRVSAYISWINNV 236 Query: 251 VQAS 254 + ++ Sbjct: 237 IASN 240 >4J1Y-A nrPDB Length = 397 Score = 87.4 bits (215), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 73/257 (28%), Positives = 114/257 (44%), Gaps = 41/257 (15%) Query: 29 SQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSY--TIGLGLHSL 86 ++ I G D + PWQ V + + G L++ WVL+AAH + + T+ +G S+ Sbjct: 145 ARAIGGSDADIKNFPWQ---VFFDNPWAGGALINEYWVLTAAHVVEGNREPTMYVGSTSV 201 Query: 87 EADQEPGSQMVEASLSVRHPEYN-------RPLLANDLMLIKLDESVSESDTIRSISIAS 139 + + S+M+ HP + R ND+ L++L + V T+ I + Sbjct: 202 QTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLPG 261 Query: 140 QCPT----AGNSCLVSGWGL---------LANGRMPT--VLQCVNVSVVSEEVCSKLYDP 184 G+ L+SGWG L R+P + +C V V ++ Y Sbjct: 262 TSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKVEKPTADAEAY-- 319 Query: 185 LYHPSMFCAGGGHDQKDSCNGDSGGPLICNG-------YLQGLVSFGKAPCGQVGVPGVY 237 ++ P+M CAGG DSC GDSGG Y GLVS+G Q G G+Y Sbjct: 320 VFTPNMICAGG-EKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGP----QCGTYGLY 374 Query: 238 TNLCKFTEWIEKTVQAS 254 T + + +WI KT+Q + Sbjct: 375 TRVKNYVDWIMKTMQEN 391 >1EQ9-A nrPDB Length = 222 Score = 87.4 bits (215), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 67/233 (28%), Positives = 110/233 (47%), Gaps = 23/233 (9%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQ-----NSYTIGLGLHS 85 I+ G+D P+Q +L + C ++ VL+AAHC N + +G + Sbjct: 1 IVGGKDAPVGKYPYQVSLRLSGSHRCGASILDNNNVLTAAHCVDGLSNLNRLKVHVGTNY 60 Query: 86 LEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPT-A 144 L E G + + +V + Y+ LL ND+ L+ L + +D ++ I +++ Sbjct: 61 L---SESG-DVYDVEDAVVNKNYDDFLLRNDVALVHLTNPIKFNDLVQPIKLSTNDEDLE 116 Query: 145 GNSCLVSGWG-LLANGRMPTVLQCVNVSVVSEEVCSK----LYDPLYHPSMFCAGGGHDQ 199 N C ++GWG G P LQ + + V ++ C + + D H G Sbjct: 117 SNPCTLTGWGSTRLGGNTPNALQEIELIVHPQKQCERDQWRVIDS--HICTLTKRG---- 170 Query: 200 KDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 252 + +C+GDSGGPL+ NG G+VSFG +PC +G P VYT + F WI ++ Sbjct: 171 EGACHGDSGGPLVANGAQIGIVSFG-SPCA-LGEPDVYTRVSSFVSWINANLK 221 >4X0L-C nrPDB Length = 259 Score = 87.4 bits (215), Expect = 6e-18, Method: Compositional matrix adjust. Identities = 69/253 (27%), Positives = 113/253 (44%), Gaps = 41/253 (16%) Query: 30 QIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEAD 89 +I+ G + S PWQA +V + L L++ QW+L+ A + + ++ D Sbjct: 14 RILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTA----KNLFLNHSENATAKD 69 Query: 90 QEP-------GSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQ-C 141 P Q+VE V HP Y++ D+ LIKL + VS ++ + I + S+ Sbjct: 70 IAPTLTLYVGKKQLVEIEKVVLHPNYSQV----DIGLIKLKQKVSVNERVMPICLPSKDY 125 Query: 142 PTAGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYD-----------------P 184 G VSGWG AN + L+ V + V ++ C + Y+ P Sbjct: 126 AEVGRVGYVSGWGRNANFKFTDHLKYVMLPVADQDQCIRHYEGSTVPEKKTPKSPVGVQP 185 Query: 185 LYHPSMFCAGGGHDQKDSCNGDSGGPLICNG------YLQGLVSFGKAPCGQVGVPGVYT 238 + + FCAG Q+D+C GD+G + Y G++SF K+ C V GVY Sbjct: 186 ILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDKS-CA-VAEYGVYV 243 Query: 239 NLCKFTEWIEKTV 251 + +W++KT+ Sbjct: 244 KVTSIQDWVQKTI 256 >4WJG-C nrPDB Length = 315 Score = 86.7 bits (213), Expect = 8e-18, Method: Compositional matrix adjust. Identities = 69/253 (27%), Positives = 113/253 (44%), Gaps = 41/253 (16%) Query: 30 QIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEAD 89 +I+ G + S PWQA +V + L L++ QW+L+ A + + ++ D Sbjct: 70 RILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTA----KNLFLNHSENATAKD 125 Query: 90 QEP-------GSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQ-C 141 P Q+VE V HP Y++ D+ LIKL + VS ++ + I + S+ Sbjct: 126 IAPTLTLYVGKKQLVEIEKVVLHPNYSQV----DIGLIKLKQKVSVNERVMPICLPSKDY 181 Query: 142 PTAGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYD-----------------P 184 G VSGWG AN + L+ V + V ++ C + Y+ P Sbjct: 182 AEVGRVGYVSGWGRNANFKFTDHLKYVMLPVADQDQCIRHYEGSTVPEKKTPKSPVGVQP 241 Query: 185 LYHPSMFCAGGGHDQKDSCNGDSGGPLICNG------YLQGLVSFGKAPCGQVGVPGVYT 238 + + FCAG Q+D+C GD+G + Y G++SF K+ C V GVY Sbjct: 242 ILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDKS-CA-VAEYGVYV 299 Query: 239 NLCKFTEWIEKTV 251 + +W++KT+ Sbjct: 300 KVTSIQDWVQKTI 312 >1AKS-B nrPDB Length = 98 Score = 86.3 bits (212), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 42/93 (45%), Positives = 57/93 (61%), Gaps = 1/93 (1%) Query: 162 PTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDSGGPLICNGYLQGLV 221 P++LQC+ V+S C Y +M C G KDSC GDSGGP++CNG LQG+V Sbjct: 7 PSLLQCLKAPVLSNSSCKSSYPGQITGNMICVGFLQGGKDSCQGDSGGPVVCNGQLQGIV 66 Query: 222 SFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 S+G C Q PGVYT +C + WI++T+ A+ Sbjct: 67 SWGYG-CAQKNKPGVYTKVCNYVNWIQQTIAAN 98 >1YM0-A nrPDB Length = 238 Score = 86.3 bits (212), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 73/243 (30%), Positives = 115/243 (47%), Gaps = 30/243 (12%) Query: 31 IINGEDCSPHSQPWQAALVME--NELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEA 88 I+ G + P+ PWQ ++ + + FC G +++ +WV+ AAHC Q + L E Sbjct: 1 IVGGIEARPYEFPWQVSVRRKSSDSHFCGGSIINDRWVVCAAHCMQGEAPALVSLVVGEH 60 Query: 89 DQEPGS---QMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQC-PTA 144 D S Q + + Y+ L ND+ +IK +++ I++ C P Sbjct: 61 DSSAASTVRQTHDVDSIFVNENYDPATLENDVSVIKTAVAIT-----FDINVGPICAPDP 115 Query: 145 GNSCLV-----SGWGLLANGRM--PTVLQCVNVSVVSEEVCSKLY--DPLYHPSMFCA-- 193 N + SGWG + +G + P VL+ V +++ + C +Y D +Y M CA Sbjct: 116 ANDYVYRKSQCSGWGTINSGGVCCPAVLRYVTLNITTNAFCDAVYTSDTIYD-DMICATD 174 Query: 194 GGGHDQKDSCNGDSGGPL-ICNG----YLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIE 248 G +DSC GDSGGPL + +G L G+VS+G C G PGVY+ + WI Sbjct: 175 NTGMTDRDSCQGDSGGPLSVKDGSGIFSLVGIVSWGIG-CAS-GYPGVYSRVGFHAGWIT 232 Query: 249 KTV 251 T+ Sbjct: 233 DTI 235 >2HLC-A nrPDB Length = 230 Score = 83.6 bits (205), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 67/230 (29%), Positives = 108/230 (46%), Gaps = 17/230 (7%) Query: 31 IINGEDCSPHSQPWQAALVM----ENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSL 86 IING + P+QA L + + ++C G L+ +W+L+AAHC ++ ++ + L S Sbjct: 1 IINGYEAYTGLFPYQAGLDITLQDQRRVWCGGSLIDNKWILTAAHCVHDAVSVVVYLGS- 59 Query: 87 EADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGN 146 A Q G +V + + H +N ND+ LIK+ V +D I+ I + S Sbjct: 60 -AVQYEGEAVVNSERIISHSMFNPDTYLNDVALIKIPH-VEYTDNIQPIRLPSGEELNNK 117 Query: 147 S----CLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYDP-LYHPSMFCAGGGHDQKD 201 VSGWG + +LQ V+ + C++ Y P + S C G D K Sbjct: 118 FENIWATVSGWG--QSNTDTVILQYTYNLVIDNDRCAQEYPPGIIVESTIC-GDTSDGKS 174 Query: 202 SCNGDSGGPLIC--NGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEK 249 C GDSGGP + L G+VSF + G P ++ + + +WI++ Sbjct: 175 PCFGDSGGPFVLSDKNLLIGVVSFVSGAGCESGKPVGFSRVTSYMDWIQQ 224 >2ASU-B nrPDB Length = 234 Score = 82.8 bits (203), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 64/228 (28%), Positives = 102/228 (44%), Gaps = 21/228 (9%) Query: 39 PHSQPWQAALV-MENELFCSGVLVHPQWVLSAAHCFQN------SYTIGLG-LHSLEADQ 90 P + PW +L + + FC G LV QW+L+A CF + Y + LG L Sbjct: 6 PGNSPWTVSLRNRQGQHFCGGSLVKEQWILTARQCFSSCHMPLTGYEVWLGTLFQNPQHG 65 Query: 91 EPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTA--GNSC 148 EP Q V + V P + L+L+KL+ SV+ + + I + + G C Sbjct: 66 EPSLQRVPVAKMVCGPS------GSQLVLLKLERSVTLNQRVALICLPPEWYVVPPGTKC 119 Query: 149 LVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDSG 208 ++GWG TVL ++V+S + C+ + S C G +C GD G Sbjct: 120 EIAGWGETKGTGNDTVLNVALLNVISNQECNIKHRGRVRESEMCTEGLLAPVGACEGDYG 179 Query: 209 GPLICNGY----LQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 252 GPL C + L+G++ + C + P V+T + F +WI K ++ Sbjct: 180 GPLACFTHNSWVLEGIIIPNRV-CARSRWPAVFTRVSVFVDWIHKVMR 226 >1SI5-H nrPDB Length = 240 Score = 82.4 bits (202), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 60/220 (27%), Positives = 93/220 (42%), Gaps = 18/220 (8%) Query: 44 WQAALVMENELFCSGVLVHPQWVLSAAHCFQ----NSYTIGLGLHSLEAD-QEPGSQMVE 98 W +L N+ C G L+ WVL+A CF Y LG+H + E Q++ Sbjct: 13 WMVSLRYRNKHICGGSLIKESWVLTARQCFPSRDLKDYEAWLGIHDVHGRGDEKCKQVLN 72 Query: 99 ASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPT--AGNSCLVSGWGLL 156 S V PE +DL+L+KL D + +I + + T SC V GWG Sbjct: 73 VSQLVYGPE------GSDLVLMKLARPAVLDDFVSTIDLPNYGSTIPEKTSCSVYGWGYT 126 Query: 157 ANGRMPTVLQCVNVSVVSEEVCSKLY--DPLYHPSMFCAGGGHDQKDSCNGDSGGPLICN 214 +L+ ++ ++ E CS+ + + S CAG C GD GGPL+C Sbjct: 127 GLINYDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAGAEKIGSGPCEGDYGGPLVCE 186 Query: 215 GYLQGLVSFGKAP---CGQVGVPGVYTNLCKFTEWIEKTV 251 + +V P C PG++ + + +WI K + Sbjct: 187 QHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKII 226 >6BQM-A nrPDB Length = 506 Score = 79.0 bits (193), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 73/251 (29%), Positives = 113/251 (45%), Gaps = 35/251 (13%) Query: 25 SGSCSQIINGEDCSPHSQPWQAALVMEN--ELFCSGVLVHPQWVLSAAHCF--QNSYTIG 80 SG S+II GE + P+ AL N +FC G + ++VL+AAHC ++ Sbjct: 5 SGVSSRIIGGEQATAGEWPYMVALTARNSSHVFCGGSYLGGRYVLTAAHCVDKEDPAKGD 64 Query: 81 LGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDE------SVSESDTIRS 134 + L + + + ++ + H Y + ND+ +++L+ SV SD+ Sbjct: 65 VLLGAFDMNDVNTAERIHVRQIYVHNSYITASMGNDIAVLELERDPLPRRSVQISDSSDF 124 Query: 135 ISIASQCPTA----GNSCLVSGWGLLANGRMPTVLQCVNVSVV---------SEEVCSKL 181 + P GN V G T+L V V V S++ Sbjct: 125 NELTKDSPMTVIGFGNRKEVDG----EKSDPATILHQVQVPFVPLPECKTKGSDQDAKNN 180 Query: 182 YDPLYHPSMFCAGGGHDQKDSCNGDSGGPLIC---NGYLQ-GLVSFGKAPCGQVGVPGVY 237 Y L + + FCAG KD+C+GD+GGP+ NG Q G+VS+G CG+ PGVY Sbjct: 181 YSQLTN-NAFCAGSF--GKDACSGDAGGPIFFDSNNGRKQMGVVSWGDG-CGRANSPGVY 236 Query: 238 TNLCKFTEWIE 248 TNL F +W++ Sbjct: 237 TNLSVFNDWLD 247 >4F4O-C nrPDB Length = 347 Score = 75.5 bits (184), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 66/253 (26%), Positives = 108/253 (42%), Gaps = 41/253 (16%) Query: 30 QIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEAD 89 +I+ G + S PWQA ++ + L L++ QW+L+ A + +G + D Sbjct: 102 RIMGGSLDAKGSFPWQAKMISHHNLTSGATLINEQWLLTTAKNLR----LGHKNDTKAKD 157 Query: 90 QEP-------GSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQ-C 141 P Q VE + HP+ + D+ LIKL + V ++ + I + S+ Sbjct: 158 IAPTLRLYVGKKQEVEIEKVIFHPDNS----TVDIGLIKLKQKVPVNERVMPICLPSKDY 213 Query: 142 PTAGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYD-----------------P 184 G VSGWG AN L+ V + V +E C + Y+ P Sbjct: 214 VNVGLVGYVSGWGRNANLNFTEHLKYVMLPVADQEKCVQYYEGSTVPEKKTPKSPVGVQP 273 Query: 185 LYHPSMFCAGGGHDQKDSCNGDSGGPLICNG------YLQGLVSFGKAPCGQVGVPGVYT 238 + + FCAG Q+D+C GD+G + Y G++SF K+ C + GVY Sbjct: 274 ILNEHTFCAGLSKYQEDTCYGDAGSAFAVHDKDDDTWYAAGILSFDKS-C-RTAEYGVYV 331 Query: 239 NLCKFTEWIEKTV 251 + +WI+ T+ Sbjct: 332 RVTSILDWIQTTI 344 >3I77-A nrPDB Length = 230 Score = 75.1 bits (183), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 71/239 (29%), Positives = 105/239 (43%), Gaps = 28/239 (11%) Query: 31 IINGEDCSPHSQPWQAALV-MENELFCSGVLVHPQWVLSAAHCF-----QNSYTIGLGLH 84 ++ G + P+ L+ ENE FC G L VL+AAHC S T G+ Sbjct: 1 VVGGTRAAQGEFPFMVRLINEENEGFCGGALYAQDIVLTAAHCVSGSGNNTSITATGGVV 60 Query: 85 SLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTA 144 L Q + V ++ ++ P + + D LIKL + +++ ++ IA+ Sbjct: 61 DL---QSSSAVKVRSTKVLQAPGFTKETYGKDWALIKLAQPINQP----TLKIATTTAYN 113 Query: 145 GNSCLVSGWGL-LANGRMPTVLQCVNVSVVSEEVC-SKLYDPLYHPSMFCAG----GGHD 198 + V+GWG G L NV VS+ C S L M CAG GG Sbjct: 114 QGTFTVAGWGANREGGSQQRYLLKANVPFVSDAACRSSSSFILVANEMICAGYPDTGG-- 171 Query: 199 QKDSCNGDSGGPLI----CNGYLQ-GLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 252 D+C GDSGGP+ + ++Q G+VS+G C + G PGVYT + F I + Sbjct: 172 -VDTCQGDSGGPMFRKDNADEWIQVGIVSWGYG-CARPGYPGVYTEVSTFASAIASAAR 228 >3VGC-B nrPDB Length = 131 Score = 75.1 bits (183), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 40/128 (31%), Positives = 69/128 (53%), Gaps = 3/128 (2%) Query: 31 IINGEDCSPHSQPWQAALVMENEL-FCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEAD 89 I+NGE+ P S PWQ +L + FC G L++ WV++AAHC + + + + Sbjct: 1 IVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGVTTSDVVVAGEFDQGS 60 Query: 90 QEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISI--ASQCPTAGNS 147 Q ++ + ++ +YN + ND+ L+KL + S S T+ ++ + AS AG + Sbjct: 61 SSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDDFAAGTT 120 Query: 148 CLVSGWGL 155 C+ +GWGL Sbjct: 121 CVTTGWGL 128 >3H7T-A nrPDB Length = 235 Score = 73.9 bits (180), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 59/208 (28%), Positives = 95/208 (45%), Gaps = 21/208 (10%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLH--SLEA 88 II G+ +PW ++++ + FC G ++ +V++AA C + + +H S Sbjct: 1 IIGGKKSDITKEPWAVGVLVDEKPFCGGSILTANFVITAAQCVDGTKPSDISIHYGSSYR 60 Query: 89 DQEPGSQMVEASLSVR-HP---EYNRPLLANDLMLIKLDESVSESDTIRSISIASQC--P 142 + S M + VR HP + N ++ + M IKLD+ T + I + S P Sbjct: 61 TTKGTSVMAKKIYIVRYHPLTMQNNYAVIETE-MPIKLDDK-----TTKKIELPSLLYDP 114 Query: 143 TAGNSCLVSGWGL--LANGRMPTVLQCVNVSVVSEEVCSKLY-----DPLYHPSMFCAGG 195 S LVSGWG + L N +VV + C + Y D + +FCAGG Sbjct: 115 EPDTSVLVSGWGSTNFKSLEYSGDLMEANFTVVDRKSCEEQYKQIEADKYIYDGVFCAGG 174 Query: 196 GHDQKDSCNGDSGGPLICNGYLQGLVSF 223 +D+ GD+G P + NG L G+ S+ Sbjct: 175 EYDETYIGYGDAGDPAVQNGTLVGVASY 202 >3BEU-A nrPDB Length = 224 Score = 71.2 bits (173), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 66/229 (28%), Positives = 100/229 (43%), Gaps = 24/229 (10%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCF-----QNSYTIGLGLHS 85 ++ G + P+ L M C G L VL+AAHC S T G+ Sbjct: 1 VVGGTRAAQGEFPFMVRLSMG----CGGALYAQDIVLTAAHCVSGSGNNTSITATGGVVD 56 Query: 86 LEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAG 145 L Q + V ++ ++ P + + D LIKL + +++ ++ IA+ Sbjct: 57 L---QSSSAVKVRSTKVLQAPGFTKETYGKDWALIKLAQPINQP----TLKIATTTAYNQ 109 Query: 146 NSCLVSGWGL-LANGRMPTVLQCVNVSVVSEEVC-SKLYDPLYHPSMFCAGGGHDQKDSC 203 + V+GWG G L NV VS+ C S L M CAG Q+D+C Sbjct: 110 GTFTVAGWGANREGGSQQRYLLKANVPFVSDAACRSSSSFILVANEMICAGYDTKQEDTC 169 Query: 204 NGDSGGPLI----CNGYLQ-GLVSFGKAPCGQVGVPGVYTNLCKFTEWI 247 GDSGGP+ + ++Q G+VS+G+ C + G GVYT + F I Sbjct: 170 QGDSGGPMFRKDNADEWVQVGIVSWGEG-CARKGKYGVYTEVSTFASAI 217 >2KAI-A nrPDB Length = 80 Score = 68.6 bits (166), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 32/79 (40%), Positives = 47/79 (59%), Gaps = 1/79 (1%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 II G +C +S PWQ A+ + C GVLV+P+WVL+AAHC ++Y + LG H+L + Sbjct: 1 IIGGRECEKNSHPWQVAIYHYSSFQCGGVLVNPKWVLTAAHCKNDNYEVWLGRHNL-FEN 59 Query: 91 EPGSQMVEASLSVRHPEYN 109 E +Q + HP +N Sbjct: 60 ENTAQFFGVTADFPHPGFN 78 >2FMJ-A nrPDB Length = 222 Score = 66.2 bits (160), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 66/234 (28%), Positives = 99/234 (42%), Gaps = 26/234 (11%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCF-----QNSYTIGLGLHS 85 ++ G + P+ L M C G L VL+AAHC S T G+ Sbjct: 1 VVGGTRAAQGEFPFMVRLSMG----CGGALYAQDIVLTAAHCVSGSGNNTSITATGGVVD 56 Query: 86 LEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAG 145 L Q + V ++ ++ P YN D LIKL + +++ ++ IA+ Sbjct: 57 L---QSSSAVKVRSTKVLQAPGYNGT--GKDWALIKLAQPINQP----TLKIATTTAYNQ 107 Query: 146 NSCLVSGWGL-LANGRMPTVLQCVNVSVVSEEVCSKLY-DPLYHPSMFCAGGGHDQKDSC 203 + V+GWG G L NV VS+ C Y + L CAG D+C Sbjct: 108 GTFTVAGWGANREGGSQQRYLLKANVPFVSDAACRSAYGNELVANEEICAGYDTGGVDTC 167 Query: 204 NGDSGGPLI----CNGYLQ-GLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 252 GDSGGP+ + ++Q G+VS+G+ C + G GVYT + F I + Sbjct: 168 QGDSGGPMFRKDNADEWIQVGIVSWGEG-CARKGKYGVYTEVSTFASAIASAAR 220 >2JET-B nrPDB Length = 128 Score = 64.7 bits (156), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 36/125 (28%), Positives = 63/125 (50%), Gaps = 5/125 (4%) Query: 34 GEDCSPHSQPWQAALVMENEL-FCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQEP 92 GED P S PWQ +L + FC G L+ WV++AAHC + + + + E Sbjct: 1 GEDAIPGSWPWQVSLQDKTGFHFCGGSLISEDWVVTAAHCGVKTSDVVVAGEFDQGSDEE 60 Query: 93 GSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSI---SIASQCPTAGNSCL 149 Q+++ + ++P++N + ND+ L+KL S+T+ ++ ++ P G C Sbjct: 61 NIQVLKIAQVFKNPKFNMFTVRNDITLLKLATPAQFSETVSAVCLPNVDDDFP-PGTVCA 119 Query: 150 VSGWG 154 +GWG Sbjct: 120 TTGWG 124 >2HNT-F nrPDB Length = 105 Score = 62.4 bits (150), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 36/99 (36%), Positives = 53/99 (53%), Gaps = 10/99 (10%) Query: 162 PTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQK---DSCNGDSGGPLICNG--- 215 P+VLQ VN+ +V VC +MFCAG D+ D+C GDSGGP + Sbjct: 3 PSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFN 62 Query: 216 ---YLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 251 Y G+VS+G+ C + G G YT++ + +WI+K + Sbjct: 63 NRWYQMGIVSWGEG-CDRDGKYGFYTHVFRLKKWIQKVI 100 >1BBR-E nrPDB Length = 109 Score = 62.4 bits (150), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 36/99 (36%), Positives = 53/99 (53%), Gaps = 10/99 (10%) Query: 162 PTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAG---GGHDQKDSCNGDSGGPLICNG--- 215 P+VLQ VN+ +V VC +MFCAG G + D+C GDSGGP + Sbjct: 7 PSVLQVVNLPLVERPVCKASTRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYN 66 Query: 216 ---YLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 251 Y G+VS+G+ C + G G YT++ + +WI+K + Sbjct: 67 NRWYQMGIVSWGEG-CDRDGKYGFYTHVFRLKKWIQKVI 104 >1RIW-B nrPDB Length = 147 Score = 61.2 bits (147), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 44/145 (30%), Positives = 63/145 (43%), Gaps = 18/145 (12%) Query: 31 IINGEDCSPHSQPWQAALVMEN--ELFCSGVLVHPQWVLSAAHCF----------QNSYT 78 I+ G D PWQ L ++ EL C L+ +WVL+AAHC +N Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 79 IGLGLHSLEADQEPGSQMVEASLSVRHPEYN-RPLLANDLMLIKLDESVSESDTIRSI-- 135 + +G HS + ++ HP YN R L D+ L+KL + V+ SD I + Sbjct: 61 VRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCL 120 Query: 136 ---SIASQCPTAGNSCLVSGWGLLA 157 A+ AG V+GWG L Sbjct: 121 PDRETAASLLQAGYKGRVTGWGNLK 145 >3H7O-A nrPDB Length = 228 Score = 60.1 bits (144), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 63/240 (26%), Positives = 101/240 (42%), Gaps = 33/240 (13%) Query: 34 GEDCSPHSQPWQAALVM---ENELFCSGVLVHPQWVLSAAHCF--QNSYTIGLGLHSLEA 88 GE PW A+ E L C G ++ +VL+AAHC Q TI + S Sbjct: 3 GEKTDIKQVPWTVAVRTYPGEESLTCGGAILSQWFVLTAAHCVFDQKPETIVIQYESTNL 62 Query: 89 DQEPGSQMVEASLSVRHPEYNRPLLANDLML------IKLDESVSESDTIRSISIASQCP 142 ++PG S V Y + + ND+ + +KLD S+ + I P Sbjct: 63 WEDPGKSDPYVS-HVYLSFYRQETMENDIAILELSRPLKLDGLKSKPAKLPDIEFR---P 118 Query: 143 TAGNSCLVSGWGLLANGRM----PTVLQCVNVSVVSEEVCSKLYDPLYHP-SMFCAGGGH 197 G+ LVSG+G +G+ L+ ++VV + C Y P++ +FCA Sbjct: 119 KTGSDVLVSGYG---DGQTMDPKDHDLKSAQLTVVDLDECRTKYGPIFLSLQVFCA---- 171 Query: 198 DQKDSC---NGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 QK +GD+G P + L G+ ++ P G P V+T + + WI+ ++ Sbjct: 172 -QKVGVSLESGDAGDPTVQQDTLVGVAAY--FPKRPEGAPEVFTKVGSYVSWIQDIIKKK 228 >2QY0-B nrPDB Length = 242 Score = 60.1 bits (144), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 64/247 (25%), Positives = 110/247 (44%), Gaps = 33/247 (13%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCF---------QNSYTIGL 81 II G+ + PWQ + G L+ +W+L+AAH S + L Sbjct: 1 IIGGQKAKMGNFPWQVFTNIHGR--GGGALLGDRWILTAAHTLYPKEHEAQSNASLDVFL 58 Query: 82 GLHSLEADQEPGSQMVEASLSVRHPEYNRPLLAN---DLMLIKLDESVSESDTIRSISIA 138 G ++E + G+ + +SV HP+Y + N D+ L++L+ SV+ + I + Sbjct: 59 GHTNVEELMKLGNHPIR-RVSV-HPDYRQDESYNFEGDIALLELENSVTLGPNLLPICLP 116 Query: 139 SQCP--TAGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCS-----KLYDPLYHPSMF 191 G VSG+G++ ++ L+ V + V + + C K ++ +MF Sbjct: 117 DNDTFYDLGLMGYVSGFGVMEE-KIAHDLRFVRLPVANPQACENWLRGKNRMDVFSQNMF 175 Query: 192 CAGGGHDQKDSCNGDSGG------PLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTE 245 CAG ++D+C GDSGG P G+VS+G G G YT + + + Sbjct: 176 CAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWG---IGCSRGYGFYTKVLNYVD 232 Query: 246 WIEKTVQ 252 WI+K ++ Sbjct: 233 WIKKEME 239 >1GPZ-A nrPDB Length = 399 Score = 60.1 bits (144), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 65/249 (26%), Positives = 111/249 (44%), Gaps = 33/249 (13%) Query: 29 SQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCF---------QNSYTI 79 QII G+ + PWQ + G L+ +W+L+AAH S + Sbjct: 156 QQIIGGQKAKMGNFPWQVFTNIHGR--GGGALLGDRWILTAAHTLYPKEHEAQSNASLDV 213 Query: 80 GLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLAN---DLMLIKLDESVSESDTIRSIS 136 LG ++E + G+ + +SV HP+Y + N D+ L++L+ SV+ + I Sbjct: 214 FLGHTNVEELMKLGNHPIR-RVSV-HPDYRQDESYNFEGDIALLELENSVTLGPNLLPIC 271 Query: 137 IASQCP--TAGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCS-----KLYDPLYHPS 189 + G VSG+G++ ++ L+ V + V + + C K ++ + Sbjct: 272 LPDNDTFYDLGLMGYVSGFGVMEE-KIAHDLRFVRLPVANPQACENWLRGKNRMDVFSQN 330 Query: 190 MFCAGGGHDQKDSCNGDSGG------PLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKF 243 MFCAG ++D+C GDSGG P G+VS+G G G YT + + Sbjct: 331 MFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWG---IGCSRGYGFYTKVLNY 387 Query: 244 TEWIEKTVQ 252 +WI+K ++ Sbjct: 388 VDWIKKEME 396 >2JET-C nrPDB Length = 99 Score = 58.9 bits (141), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 35/99 (35%), Positives = 50/99 (50%), Gaps = 7/99 (7%) Query: 160 RMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDSGGPLICNG---- 215 + P LQ + +VSE C K + M CAG DSC GDSGGPL+C Sbjct: 4 KTPEKLQQAALPIVSEADCKKSWGSKITDVMTCAGASG--VDSCMGDSGGPLVCQKDGVW 61 Query: 216 YLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 L G+VS+G C PGVY+ + W+++ ++A+ Sbjct: 62 TLAGIVSWGSGVC-STSTPGVYSRVTALMPWVQQILEAN 99 >1MD7-A nrPDB Length = 328 Score = 58.5 bits (140), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 63/249 (25%), Positives = 111/249 (44%), Gaps = 33/249 (13%) Query: 29 SQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCF---------QNSYTI 79 +II G+ + PWQ + G L+ +W+L+AAH S + Sbjct: 88 QRIIGGQKAKMGNFPWQVFTNIHGR--GGGALLGDRWILTAAHTLYPKEHEAQSNASLDV 145 Query: 80 GLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLAN---DLMLIKLDESVSESDTIRSIS 136 LG ++E + G+ + +SV HP+Y + N D+ L++L+ SV+ + I Sbjct: 146 FLGHTNVEELMKLGNHPIR-RVSV-HPDYRQDESYNFEGDIALLELENSVTLGPNLLPIC 203 Query: 137 IASQCP--TAGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCS-----KLYDPLYHPS 189 + G VSG+G++ ++ L+ V + V + + C K ++ + Sbjct: 204 LPDNDTFYDLGLMGYVSGFGVMEE-KIAHDLRFVRLPVANPQACENWLRGKNRMDVFSQN 262 Query: 190 MFCAGGGHDQKDSCNGDSGG------PLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKF 243 MFCAG ++D+C GD+GG P G+VS+G G G YT + + Sbjct: 263 MFCAGHPSLKQDACQGDAGGVFAVRDPNTDRWVATGIVSWG---IGCSRGYGFYTKVLNY 319 Query: 244 TEWIEKTVQ 252 +WI+K ++ Sbjct: 320 VDWIKKEME 328 >1EPT-B nrPDB Length = 82 Score = 58.5 bits (140), Expect = 3e-09, Method: Composition-based stats. Identities = 27/76 (35%), Positives = 43/76 (56%), Gaps = 1/76 (1%) Query: 79 IGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIA 138 + LG H+++ E Q + A+ + HP +N L ND+MLIKL + + + ++S+ Sbjct: 5 VRLGEHNIDV-LEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLP 63 Query: 139 SQCPTAGNSCLVSGWG 154 C AG CL+SGWG Sbjct: 64 RSCAAAGTECLISGWG 79 >1BBR-H nrPDB Length = 150 Score = 58.2 bits (139), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 41/142 (28%), Positives = 64/142 (45%), Gaps = 18/142 (12%) Query: 31 IINGEDCSPHSQPWQAALVMEN--ELFCSGVLVHPQWVLSAAHC-----FQNSYTIG--- 80 I+ G+D PWQ L ++ EL C L+ +WVL+AAHC + ++T+ Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDLL 60 Query: 81 --LGLHSLEADQEPGSQMVEASLSVRHPEYN-RPLLANDLMLIKLDESVSESDTIRSI-- 135 +G HS + ++ HP YN + L D+ L+KL + SD I + Sbjct: 61 VRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVCL 120 Query: 136 ---SIASQCPTAGNSCLVSGWG 154 A++ AG V+GWG Sbjct: 121 PDKQTAAKLLHAGFKGRVTGWG 142 >2OK5-A nrPDB Length = 752 Score = 57.8 bits (138), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 73/283 (25%), Positives = 104/283 (36%), Gaps = 86/283 (30%) Query: 40 HSQPWQAALVM----ENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQEPGSQ 95 H QPWQA + + + C G +V +VL+AAHCF T+ HS++ + Sbjct: 476 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCF----TVDDKEHSIKVSVGGEKR 531 Query: 96 MVEASLSVRHPEYN---------RPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGN 146 +E + + HP YN D+ LIKL + TIR I Sbjct: 532 DLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPI----------- 580 Query: 147 SCLVSGWGLLANGRMPTVLQC------------VNVSVVSEE------------------ 176 CL G R+P C + VSEE Sbjct: 581 -CLPCTEGTTRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKG 639 Query: 177 VCSK--LYDPLYH----------PSMFCAGGGHDQKD--SCNGDSGGPLICNG---YLQ- 218 C + Y P Y P C GG D +C GDSGGPLI + ++Q Sbjct: 640 SCERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQV 699 Query: 219 GLVSFG-----KAPCGQVGVPG----VYTNLCKFTEWIEKTVQ 252 G++S+G K Q VP + NL + W+++ +Q Sbjct: 700 GVISWGVVDVCKNQKRQKQVPAHARDFHINLFQVLPWLKEKLQ 742 >3RU4-E nrPDB Length = 96 Score = 57.4 bits (137), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 35/97 (36%), Positives = 51/97 (52%), Gaps = 7/97 (7%) Query: 162 PTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDSGGPLIC--NG--YL 217 P LQ ++ ++S C K + +M CAG SC GDSGGPL+C NG L Sbjct: 3 PDRLQQASLPLLSNTNCKKYWGTKIKDAMICAGA--SGVSSCMGDSGGPLVCKKNGAWTL 60 Query: 218 QGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 G+VS+G + C PGVY + W+++T+ A+ Sbjct: 61 VGIVSWGSSTC-STSTPGVYARVTALVNWVQQTLAAN 96 >1DLE-A nrPDB Length = 298 Score = 57.4 bits (137), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 73/283 (25%), Positives = 104/283 (36%), Gaps = 86/283 (30%) Query: 40 HSQPWQAALVM----ENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQEPGSQ 95 H QPWQA + + + C G +V +VL+AAHCF T+ HS++ + Sbjct: 25 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCF----TVDDKEHSIKVSVGGEKR 80 Query: 96 MVEASLSVRHPEYN---------RPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGN 146 +E + + HP YN D+ LIKL + TIR I Sbjct: 81 DLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPI----------- 129 Query: 147 SCLVSGWGLLANGRMPTVLQC------------VNVSVVSEE------------------ 176 CL G R+P C + VSEE Sbjct: 130 -CLPCTEGTTRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKG 188 Query: 177 VCSK--LYDPLYH----------PSMFCAGGGHDQKD--SCNGDSGGPLICNG---YLQ- 218 C + Y P Y P C GG D +C GDSGGPLI + ++Q Sbjct: 189 SCERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQV 248 Query: 219 GLVSFG-----KAPCGQVGVPG----VYTNLCKFTEWIEKTVQ 252 G++S+G K Q VP + NL + W+++ +Q Sbjct: 249 GVISWGVVDVCKNQKRQKQVPAHARDFHINLFQVLPWLKEKLQ 291 >2WIN-I nrPDB Length = 507 Score = 57.4 bits (137), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 73/283 (25%), Positives = 104/283 (36%), Gaps = 86/283 (30%) Query: 40 HSQPWQAALVM----ENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQEPGSQ 95 H QPWQA + + + C G +V +VL+AAHCF T+ HS++ + Sbjct: 232 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCF----TVDDKEHSIKVSVGGEKR 287 Query: 96 MVEASLSVRHPEYN---------RPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGN 146 +E + + HP YN D+ LIKL + TIR I Sbjct: 288 DLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPI----------- 336 Query: 147 SCLVSGWGLLANGRMPTVLQC------------VNVSVVSEE------------------ 176 CL G R+P C + VSEE Sbjct: 337 -CLPCTEGTTRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKG 395 Query: 177 VCSK--LYDPLYH----------PSMFCAGGGHDQKD--SCNGDSGGPLICNG---YLQ- 218 C + Y P Y P C GG D +C GDSGGPLI + ++Q Sbjct: 396 SCERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQV 455 Query: 219 GLVSFG-----KAPCGQVGVPG----VYTNLCKFTEWIEKTVQ 252 G++S+G K Q VP + NL + W+++ +Q Sbjct: 456 GVISWGVVDVCKNQKRQKQVPAHARDFHINLFQVLPWLKEKLQ 498 >1M9U-A nrPDB Length = 241 Score = 55.5 bits (132), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 61/240 (25%), Positives = 100/240 (41%), Gaps = 26/240 (10%) Query: 31 IINGEDCSPHSQPWQAALVMENELF---CSGVLVHPQWVLSAAHCFQ----NSYTIGLGL 83 +I G + SP PWQ + ++ + C L+ LSA+HC N+ + GL Sbjct: 1 VIGGTNASPGEFPWQLSQQRQSGSWSHSCGASLLSSTSALSASHCVDGVLPNNIRVIAGL 60 Query: 84 HSLEADQEPGSQMVEASLSVRHPEYN--RPLLANDLMLIKLDESVSESDTIRSISIASQC 141 + G+Q H Y +ND+ ++ L S+S I++ + + Sbjct: 61 --WQQSDTSGTQTANVDSYTMHENYGAGTASYSNDIAILHLATSISLGGNIQAAVLPANN 118 Query: 142 PT--AGNSCLVSGWGLL-ANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMF----CAG 194 AG +C++SGWG +P +LQ ++ V++ C+ + +++ C Sbjct: 119 NNDYAGTTCVISGWGRTDGTNNLPDILQKSSIPVITTAQCTAAMVGVGGANIWDNHICVQ 178 Query: 195 GGHDQKDSCNGDSGGPLICN-------GYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWI 247 +CNGDSGGPL C G +VS G C P VYT + + WI Sbjct: 179 DPAGNTGACNGDSGGPLNCPDGGTRVVGVTSWVVSSGLGAC-LPDYPSVYTRVSAYLGWI 237 >2I6S-A nrPDB Length = 517 Score = 44.3 bits (103), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 65/273 (23%), Positives = 108/273 (39%), Gaps = 76/273 (27%) Query: 43 PWQAALVMENELFCSGVLVHPQWVLSAAHCFQNS-----YTIGLGLHSLEADQEPGSQMV 97 PW + +++ C G L+ QWVL+AAHCF++ + + +G +P SQ Sbjct: 244 PWHVTIKPKSQETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVG--------DPKSQWG 295 Query: 98 EASL---SVRHPEY------NRPLL---ANDLMLIKLDESVSESDTIRSI--------SI 137 + L +V P + N+ +L +D+ L+KL + V S R I ++ Sbjct: 296 KEFLIEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPICLPCTMEANL 355 Query: 138 ASQCPTAGNSCLVSGWGLLANGRMPTVLQCVN-----------------VSVVSEE--VC 178 A + P G++C LL +P +N VVS+E + Sbjct: 356 ALRRP-QGSTCRDHENELLNKQSVPAHFVALNGSKLNINLKMGVEWTSCAEVVSQEKTMF 414 Query: 179 SKLYD--PLYHPSMFCAGGGHDQKDSCNGDSGGPLICNGYLQ----GLVSFG-------- 224 L D + C+G D+ C G+SGG + + GLVS+G Sbjct: 415 PNLTDVREVVTDQFLCSGTQEDES-PCKGESGGAVFLERRFRFFQVGLVSWGLYNPCLGS 473 Query: 225 -------KAPCGQVGVP-GVYTNLCKFTEWIEK 249 +AP +V P + NL + W+ + Sbjct: 474 ADKNSRKRAPRSKVPPPRDFHINLFRMQPWLRQ 506 >2HNT-C nrPDB Length = 70 Score = 40.4 bits (93), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 22/67 (32%), Positives = 31/67 (46%), Gaps = 12/67 (17%) Query: 31 IINGEDCSPHSQPWQAALVMEN--ELFCSGVLVHPQWVLSAAHCF----------QNSYT 78 I+ G D PWQ L ++ EL C L+ +WVL+AAHC +N Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 79 IGLGLHS 85 + +G HS Sbjct: 61 VRIGKHS 67 >3H5C-B nrPDB Length = 317 Score = 40.0 bits (92), Expect = 9e-04, Method: Compositional matrix adjust. Identities = 32/118 (27%), Positives = 51/118 (43%), Gaps = 18/118 (15%) Query: 31 IINGEDCSPHSQ--PWQAALV-MENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLE 87 ++ E +P Q PWQ L E + FC GV++ +VL+ A C I + + Sbjct: 92 VLTSEKRAPDLQDLPWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYFNR 151 Query: 88 ADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAG 145 Q+P M++ + H Y+ NDL L++L+ + QCP AG Sbjct: 152 TSQDP--LMIKITHVHVHMRYDADAGENDLSLLELEWPI-------------QCPGAG 194 >3F1S-B nrPDB Length = 283 Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust. Identities = 32/118 (27%), Positives = 51/118 (43%), Gaps = 18/118 (15%) Query: 31 IINGEDCSPHSQ--PWQAALV-MENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLE 87 ++ E +P Q PWQ L E + FC GV++ +VL+ A C I + + Sbjct: 51 VLTSEKRAPDLQDLPWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYFNR 110 Query: 88 ADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAG 145 Q+P M++ + H Y+ NDL L++L+ + QCP AG Sbjct: 111 TSQDP--LMIKITHVHVHMRYDADAGENDLSLLELEWPI-------------QCPGAG 153 >1H2B-A nrPDB Length = 359 Score = 28.9 bits (63), Expect = 2.2, Method: Compositional matrix adjust. Identities = 26/80 (32%), Positives = 36/80 (45%), Gaps = 6/80 (7%) Query: 97 VEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLVSG-WGL 155 VE + R EYN+PL D+ +L+ D I I+ A C T + LV G W Sbjct: 13 VERLKAARLHEYNKPLRIEDVDYPRLE---GRFDVIVRIAGAGVCHT--DLHLVQGMWHE 67 Query: 156 LANGRMPTVLQCVNVSVVSE 175 L ++P L NV + E Sbjct: 68 LLQPKLPYTLGHENVGYIEE 87 >5JM5-A nrPDB Length = 332 Score = 27.3 bits (59), Expect = 5.9, Method: Compositional matrix adjust. Identities = 20/64 (31%), Positives = 27/64 (42%), Gaps = 10/64 (15%) Query: 67 LSAAHCFQNSYTIGLGLHSLEADQEPGSQMVEASL-------SVRHPEYNRPLLANDLML 119 + +AH + N +GL + S AD GS E + PE RP L N L Sbjct: 49 IDSAHLYNNEEQVGLAIRSKIAD---GSVKREDIFYTSKLWSTFHRPELVRPALENSLKK 105 Query: 120 IKLD 123 +LD Sbjct: 106 AQLD 109 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5FXL-A nrPDB 343 4e-95 2BDH-A nrPDB 337 2e-93 4AN7-A nrPDB 332 1e-91 1F7Z-A nrPDB 330 3e-91 1UTJ-A nrPDB 323 6e-89 4WWY-A nrPDB 320 3e-88 5C67-A nrPDB 319 6e-88 1A0J-A nrPDB 318 1e-87 1SGF-G nrPDB 314 2e-86 4NFE-A nrPDB 312 9e-86 1FXY-A nrPDB 305 1e-83 1SPJ-A nrPDB 304 2e-83 2PSX-A nrPDB 304 2e-83 1NPM-A nrPDB 302 1e-82 5MS3-A nrPDB 299 8e-82 3QUM-P nrPDB 298 1e-81 3BSQ-A nrPDB 298 2e-81 2TLD-E nrPDB 295 8e-81 1AO5-A nrPDB 295 1e-80 6QHB-A nrPDB 294 3e-80 1SGF-A nrPDB 293 4e-80 1TON-A nrPDB 291 2e-79 5ZFH-A nrPDB 290 5e-79 4GSO-A nrPDB 289 8e-79 2EEK-A nrPDB 288 1e-78 1EUF-A nrPDB 285 8e-78 2AIQ-A nrPDB 282 1e-76 4E7N-A nrPDB 282 1e-76 1FI8-A nrPDB 281 2e-76 6I44-A nrPDB 278 2e-75 5TJX-A nrPDB 278 2e-75 1GVZ-A nrPDB 276 6e-75 1OP0-A nrPDB 276 7e-75 3S9B-A nrPDB 275 1e-74 3W94-A nrPDB 274 2e-74 4DGJ-A nrPDB 274 3e-74 1X7A-C nrPDB 274 3e-74 3S69-A nrPDB 272 8e-74 2F83-A nrPDB 272 9e-74 1NN6-A nrPDB 272 1e-73 1IAU-A nrPDB 271 2e-73 1BQY-A nrPDB 270 3e-73 3LC3-A nrPDB 270 3e-73 5GVT-A nrPDB 269 8e-73 1EKB-B nrPDB 267 3e-72 2CGA-A nrPDB 267 4e-72 3T2N-A nrPDB 267 4e-72 1KIG-H nrPDB 267 5e-72 3TK9-A nrPDB 266 6e-72 3K65-B nrPDB 265 1e-71 3NXP-A nrPDB 265 2e-71 4NZQ-A nrPDB 263 4e-71 4DUR-A nrPDB 263 5e-71 5UGG-A nrPDB 263 5e-71 1MKW-K nrPDB 263 5e-71 2F91-A nrPDB 262 1e-70 1C5M-D nrPDB 262 1e-70 3G01-A nrPDB 262 1e-70 4MPW-A nrPDB 261 2e-70 5LPF-A nrPDB 261 2e-70 2OQ5-A nrPDB 260 3e-70 3E0N-B nrPDB 260 4e-70 3DFJ-A nrPDB 259 9e-70 6AOD-C nrPDB 259 1e-69 1P57-B nrPDB 258 1e-69 3P8G-A nrPDB 257 3e-69 2OCV-B nrPDB 257 4e-69 1LTO-A nrPDB 257 5e-69 1FDP-A nrPDB 256 6e-69 1KYN-A nrPDB 256 7e-69 4H4F-A nrPDB 256 7e-69 1ETT-H nrPDB 256 9e-69 1PYT-D nrPDB 255 1e-68 1BRU-P nrPDB 255 1e-68 1VR1-H nrPDB 255 1e-68 5FCR-A nrPDB 254 2e-68 1FIZ-A nrPDB 252 1e-67 4Z6A-H nrPDB 251 2e-67 1FIW-A nrPDB 250 4e-67 1MZD-A nrPDB 250 5e-67 1ORF-A nrPDB 250 6e-67 3F6U-H nrPDB 248 2e-66 4Q7Y-A nrPDB 247 4e-66 2RDL-A nrPDB 245 1e-65 5TO3-B nrPDB 245 1e-65 1AZZ-A nrPDB 245 2e-65 1FUJ-A nrPDB 244 2e-65 1BDA-A nrPDB 244 3e-65 1SC8-U nrPDB 243 5e-65 5LHN-A nrPDB 242 9e-65 4XDE-A nrPDB 242 2e-64 4IGD-A nrPDB 241 3e-64 3RP2-A nrPDB 240 3e-64 2XRC-A nrPDB 240 4e-64 1YC0-A nrPDB 240 5e-64 1Q3X-A nrPDB 238 2e-63 4IW4-E nrPDB 238 2e-63 4DJZ-B nrPDB 237 3e-63 4KKD-A nrPDB 237 3e-63 5XRF-A nrPDB 237 4e-63 2XXL-A nrPDB 237 4e-63 4BXW-A nrPDB 236 6e-63 2ZKS-A nrPDB 236 6e-63 1ZJK-A nrPDB 236 8e-63 2V35-A nrPDB 236 1e-62 1A5I-A nrPDB 235 1e-62 4FXG-H nrPDB 235 1e-62 2R0L-A nrPDB 235 2e-62 5O32-I nrPDB 234 3e-62 5UBM-A nrPDB 228 1e-60 1ELV-A nrPDB 226 6e-60 1FON-A nrPDB 225 1e-59 1ELT-A nrPDB 224 3e-59 1AE5-A nrPDB 222 1e-58 4J1Y-A nrPDB 222 1e-58 1EQ9-A nrPDB 221 2e-58 2OLG-A nrPDB 221 2e-58 1PPF-E nrPDB 218 2e-57 5KWM-A nrPDB 217 3e-57 4X0L-C nrPDB 215 2e-56 2B9L-A nrPDB 215 2e-56 4WJG-C nrPDB 214 2e-56 4LK4-A nrPDB 211 3e-55 4F4O-C nrPDB 211 3e-55 1PQ7-A nrPDB 210 3e-55 1GPZ-A nrPDB 210 4e-55 2QY0-B nrPDB 209 9e-55 1MD7-A nrPDB 209 1e-54 1YM0-A nrPDB 208 2e-54 6BQM-A nrPDB 207 3e-54 2HLC-A nrPDB 206 6e-54 2ASU-B nrPDB 205 1e-53 3I77-A nrPDB 205 2e-53 2PKA-B nrPDB 202 1e-52 1SI5-H nrPDB 201 2e-52 3BEU-A nrPDB 201 2e-52 2FMJ-A nrPDB 195 2e-50 5XW8-A nrPDB 186 8e-48 3H7T-A nrPDB 175 2e-44 1M9U-A nrPDB 175 2e-44 3H7O-A nrPDB 173 6e-44 3VGC-B nrPDB 155 1e-38 1AKS-B nrPDB 154 3e-38 2JET-B nrPDB 153 6e-38 1RIW-B nrPDB 151 3e-37 2I6S-A nrPDB 147 4e-36 1BBR-H nrPDB 146 6e-36 2WIN-I nrPDB 145 1e-35 1DLE-A nrPDB 144 3e-35 2OK5-A nrPDB 142 2e-34 1BBR-E nrPDB 121 4e-28 2HNT-F nrPDB 120 6e-28 2JET-C nrPDB 116 9e-27 3RU4-E nrPDB 116 1e-26 2KAI-A nrPDB 114 4e-26 3F1S-B nrPDB 108 2e-24 1EPT-B nrPDB 106 9e-24 3H5C-B nrPDB 105 2e-23 2HNT-C nrPDB 76 1e-14 Sequences not found previously or not previously below threshold: 2HNT-E nrPDB 78 5e-15 1P3E-A nrPDB 44 8e-05 3LT3-A nrPDB 37 0.006 2EA3-A nrPDB 37 0.006 2PFE-A nrPDB 37 0.007 2OUA-A nrPDB 36 0.014 2SFA-A nrPDB 36 0.017 5ILB-A nrPDB 34 0.046 4FLN-A nrPDB 34 0.046 2SGA-A nrPDB 34 0.063 5JYK-A nrPDB 33 0.16 5ILA-A nrPDB 32 0.26 1DUE-A nrPDB 31 0.71 2HRV-A nrPDB 29 1.6 3W95-A nrPDB 28 3.4 4FVB-A nrPDB 28 3.5 4NWK-A nrPDB 28 3.7 6C2N-A nrPDB 28 3.9 4B6E-A nrPDB 28 4.0 2M5T-A nrPDB 28 4.1 3H7V-A nrPDB 28 4.2 6FE6-A nrPDB 28 4.6 4NSY-A nrPDB 28 4.6 4U01-A nrPDB 28 5.1 4K8B-A nrPDB 28 5.2 4EXK-A nrPDB 27 5.4 1HPG-A nrPDB 27 5.7 5MRT-A nrPDB 27 8.2 5VAI-R nrPDB 27 9.4 5NX2-A nrPDB 27 9.5 >5FXL-A nrPDB Length = 246 Score = 343 bits (881), Expect = 4e-95, Method: Composition-based stats. Identities = 95/246 (38%), Positives = 142/246 (57%), Gaps = 5/246 (2%) Query: 11 FLGYLILGVAGSLVSGSCSQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAA 70 F+ +LG A + +I+ G C ++ P+Q +L FC G L++ QWV+SAA Sbjct: 4 FIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSL-NSGYHFCGGSLINSQWVVSAA 62 Query: 71 HCFQNSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESD 130 HC+++ + LG ++ E Q + AS S+ HP YN L ND+MLIKL + S + Sbjct: 63 HCYKSGIQVRLGEDNINVV-EGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNS 121 Query: 131 TIRSISIASQCPTAGNSCLVSGWGLLANG--RMPTVLQCVNVSVVSEEVCSKLYDPLYHP 188 + SIS+ + C +AG CL+SGWG + P VL+C+ ++S+ C Y Sbjct: 122 RVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITS 181 Query: 189 SMFCAGGGHDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIE 248 +MFCAG KDSC GDSGGP++C+G LQG+VS+G C Q PGVYT +C + WI+ Sbjct: 182 NMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSG-CAQKNKPGVYTKVCNYVSWIK 240 Query: 249 KTVQAS 254 +T+ ++ Sbjct: 241 QTIASN 246 >2BDH-A nrPDB Length = 223 Score = 337 bits (866), Expect = 2e-93, Method: Composition-based stats. Identities = 222/223 (99%), Positives = 222/223 (99%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ Sbjct: 1 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 60 Query: 91 EPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLV 150 EPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLV Sbjct: 61 EPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLV 120 Query: 151 SGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDSGGP 210 SGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGG DQKDSCNGDSGGP Sbjct: 121 SGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGQDQKDSCNGDSGGP 180 Query: 211 LICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQA 253 LICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQA Sbjct: 181 LICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQA 223 >4AN7-A nrPDB Length = 231 Score = 332 bits (852), Expect = 1e-91, Method: Composition-based stats. Identities = 88/234 (37%), Positives = 134/234 (57%), Gaps = 5/234 (2%) Query: 23 LVSGSCSQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLG 82 + +I+ G C+ +S P+Q +L FC G L++ QWV+SAAHC+++ + LG Sbjct: 1 FPTDDDDKIVGGYTCAANSIPYQVSL-NSGSHFCGGSLINSQWVVSAAHCYKSRIQVRLG 59 Query: 83 LHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCP 142 H+++ E Q + A+ + HP +N L ND+MLIKL + + + ++S+ C Sbjct: 60 EHNIDVL-EGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRSCA 118 Query: 143 TAGNSCLVSGWGLLANG--RMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQK 200 AG CL+SGWG + P++LQC+ V+S+ C Y +M C G K Sbjct: 119 AAGTECLISGWGNTKSSGSSYPSLLQCLKAPVLSDSSCKSSYPGQITGNMICVGFLEGGK 178 Query: 201 DSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 DSC GDSGGP++CNG LQG+VS+G C Q PGVYT +C + WI++T+ A+ Sbjct: 179 DSCQGDSGGPVVCNGQLQGIVSWGYG-CAQKNKPGVYTKVCNYVNWIQQTIAAN 231 >1F7Z-A nrPDB Length = 233 Score = 330 bits (848), Expect = 3e-91, Method: Composition-based stats. Identities = 87/235 (37%), Positives = 132/235 (56%), Gaps = 5/235 (2%) Query: 22 SLVSGSCSQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGL 81 + I+ G C +S P+Q +L FC G L++ QWV+SAAHC+++ + L Sbjct: 2 AFPVDDDDAIVGGYTCQENSVPYQVSL-NSGYHFCGGSLINDQWVVSAAHCYKSRIQVRL 60 Query: 82 GLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQC 141 G H++ E Q V A+ ++HP ++R L ND+MLIKL V + + ++++ S C Sbjct: 61 GEHNINVL-EGNEQFVNAAKIIKHPNFDRKTLNNDIMLIKLSSPVKLNARVATVALPSSC 119 Query: 142 PTAGNSCLVSGWGLL--ANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQ 199 AG CL+SGWG + P +LQC++ ++ + C Y +M C G Sbjct: 120 APAGTQCLISGWGNTLSSGVNEPDLLQCLDAPLLPQADCEASYPGKITDNMVCVGFLEGG 179 Query: 200 KDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 KDSC GDSGGP++CNG LQG+VS+G C PGVYT +C + +WI+ T+ A+ Sbjct: 180 KDSCQGDSGGPVVCNGELQGIVSWGYG-CALPDNPGVYTKVCNYVDWIQDTIAAN 233 >1UTJ-A nrPDB Length = 242 Score = 323 bits (828), Expect = 6e-89, Method: Composition-based stats. Identities = 91/244 (37%), Positives = 143/244 (58%), Gaps = 7/244 (2%) Query: 11 FLGYLILGVAGSLVSGSCSQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAA 70 + L++G A + +I+ G +C P+SQP Q +L FC G LV+ WV+SAA Sbjct: 4 LVFVLLIGAAFA---TEDDKIVGGYECKPYSQPHQVSL-NSGYHFCGGSLVNENWVVSAA 59 Query: 71 HCFQNSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESD 130 HC+++ + LG H+++ E Q + +S +RHP Y+ + ND+MLIKL + + + Sbjct: 60 HCYKSRVEVRLGEHNIKV-TEGSEQFISSSRVIRHPNYSSYNIDNDIMLIKLSKPATLNT 118 Query: 131 TIRSISIASQCPTAGNSCLVSGWGLL-ANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPS 189 ++ +++ + C AG C VSGWG ++ LQC+N+ ++S C+ Y + + Sbjct: 119 YVQPVALPTSCAPAGTMCTVSGWGNTMSSTADSNKLQCLNIPILSYSDCNNSYPGMITNA 178 Query: 190 MFCAGGGHDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEK 249 MFCAG KDSC GDSGGP++CNG LQG+VS+G C + G PGVY +C F +W+ Sbjct: 179 MFCAGYLEGGKDSCQGDSGGPVVCNGELQGVVSWGYG-CAEPGNPGVYAKVCIFNDWLTS 237 Query: 250 TVQA 253 T+ + Sbjct: 238 TMAS 241 >4WWY-A nrPDB Length = 224 Score = 320 bits (821), Expect = 3e-88, Method: Composition-based stats. Identities = 90/226 (39%), Positives = 132/226 (58%), Gaps = 5/226 (2%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 I+ G +C +S P+Q +L FC G L++ QWV+SA HC+++ + LG H++E Sbjct: 1 IVGGYNCEENSVPYQVSL-NSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVL- 58 Query: 91 EPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLV 150 E Q + A+ +RHP+Y+R L ND+MLIKL + + +IS+ + P G CL+ Sbjct: 59 EGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINAHVSTISLPTAPPATGTKCLI 118 Query: 151 SGWGLLANG--RMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDSG 208 SGWG A+ P LQC++ V+S+ C Y +MFC G KDSC DSG Sbjct: 119 SGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQRDSG 178 Query: 209 GPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 GP++CNG LQG+VS+G C Q PGVYT + + +WI+ T+ A+ Sbjct: 179 GPVVCNGQLQGVVSWGDG-CAQKNKPGVYTKVYNYVKWIKNTIAAN 223 >5C67-A nrPDB Length = 224 Score = 319 bits (819), Expect = 6e-88, Method: Composition-based stats. Identities = 88/226 (38%), Positives = 128/226 (56%), Gaps = 5/226 (2%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 I+ G C +S P+Q +L FC G L+ QWV+SAAHC++ + LG H+++ Sbjct: 1 IVGGYTCEENSLPYQVSL-NSGSHFCGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKVL- 58 Query: 91 EPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLV 150 E Q + A+ +RHP+YNR L ND+MLIKL + + +IS+ + P AG CL+ Sbjct: 59 EGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPPAAGTECLI 118 Query: 151 SGWGLL--ANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDSG 208 SGWG P L+C++ V+++ C Y SMFC G KDSC D+G Sbjct: 119 SGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSCQRDAG 178 Query: 209 GPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 GP++CNG LQG+VS+G C PGVYT + + +WI+ T+ A+ Sbjct: 179 GPVVCNGQLQGVVSWGHG-CAWKNRPGVYTKVYNYVDWIKDTIAAN 223 >1A0J-A nrPDB Length = 223 Score = 318 bits (816), Expect = 1e-87, Method: Composition-based stats. Identities = 88/226 (38%), Positives = 134/226 (59%), Gaps = 5/226 (2%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 I+ G +C +S +QA+L FC G L+ WV+SAAHC+++ + LG H++ Sbjct: 1 IVGGYECRKNSASYQASLQ-SGYHFCGGSLISSTWVVSAAHCYKSRIQVRLGEHNIAV-N 58 Query: 91 EPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLV 150 E Q +++ + HP YN L ND+MLIKL + S + + ++++ S C ++G CLV Sbjct: 59 EGTEQFIDSVKVIMHPSYNSRNLDNDIMLIKLSKPASLNSYVSTVALPSSCASSGTRCLV 118 Query: 151 SGWGLLA--NGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDSG 208 SGWG L+ + P L+C+++ ++S C+ Y +MFCAG KDSC GDSG Sbjct: 119 SGWGNLSGSSSNYPDTLRCLDLPILSSSSCNSAYPGQITSNMFCAGFMEGGKDSCQGDSG 178 Query: 209 GPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 GP++CNG LQG+VS+G C Q PGVYT +C + WI T+ ++ Sbjct: 179 GPVVCNGQLQGVVSWGYG-CAQRNKPGVYTKVCNYRSWISSTMSSN 223 >1SGF-G nrPDB Length = 237 Score = 314 bits (805), Expect = 2e-86, Method: Composition-based stats. Identities = 93/237 (39%), Positives = 139/237 (58%), Gaps = 14/237 (5%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 I+ G C +SQPW A+ + C GVL+ P WVL+AAHC+ ++Y + LG ++L Sbjct: 1 IVGGFKCEKNSQPWHVAVYRYTQYLCGGVLLDPNWVLTAAHCYDDNYKVWLGKNNL-FKD 59 Query: 91 EPGSQMVEASLSVRHPEYNRPL-----------LANDLMLIKLDESVSESDTIRSISIAS 139 EP +Q S ++ HP +N L +NDLML++L + +DT++ I++ + Sbjct: 60 EPSAQHRFVSKAIPHPGFNMSLMRKHIRFLEYDYSNDLMLLRLSKPADITDTVKPITLPT 119 Query: 140 QCPTAGNSCLVSGWGLLANGRMP--TVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGH 197 + P G++CL SGWG + + L CVN+ ++ E C+K + +M CAG Sbjct: 120 EEPKLGSTCLASGWGSITPTKFQFTDDLYCVNLKLLPNEDCAKAHIEKVTDAMLCAGEMD 179 Query: 198 DQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 KD+C GDSGGPLIC+G LQG+ S+G PCG+ +PGVYT L KFT WI+ T+ + Sbjct: 180 GGKDTCKGDSGGPLICDGVLQGITSWGHTPCGEPDMPGVYTKLNKFTSWIKDTMAKN 236 >4NFE-A nrPDB Length = 237 Score = 312 bits (800), Expect = 9e-86, Method: Composition-based stats. Identities = 95/237 (40%), Positives = 134/237 (56%), Gaps = 14/237 (5%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 I+ G +C HSQPWQ A+ C GVLVHPQWVL+AAHC + + + LG H+L + Sbjct: 1 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNL-FEP 59 Query: 91 EPGSQMVEASLSVRHPEYNRPLL-----------ANDLMLIKLDESVSESDTIRSISIAS 139 E Q V S S HP YN LL ++DLML++L E +D ++ + + + Sbjct: 60 EDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPT 119 Query: 140 QCPTAGNSCLVSGWGLLANGRM--PTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGH 197 Q P G +C SGWG + P LQCV++ ++S ++C++ Y M CAG Sbjct: 120 QEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWT 179 Query: 198 DQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 KD+C GDSGGPL+CNG LQG+ S+G PC P VYT + + +WI+ T+ A+ Sbjct: 180 GGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 236 >1FXY-A nrPDB Length = 228 Score = 305 bits (781), Expect = 1e-83, Method: Composition-based stats. Identities = 79/228 (34%), Positives = 123/228 (53%), Gaps = 5/228 (2%) Query: 31 IINGEDCSPHSQPWQAALVME-NELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEAD 89 I+ G +C PWQA L+ E NE FC G ++ ++L+AAHC + + + + Sbjct: 1 IVGGYNCKDGEVPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTE 60 Query: 90 QEPGSQMV-EASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSC 148 QE G + V E + ++H + + D+ +++L ++ + S+ + P G C Sbjct: 61 QEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPASLPTAPPATGTKC 120 Query: 149 LVSGWGLLANG--RMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGD 206 L+SGWG A+ P LQC++ V+S+ C Y +MFC G KDSC GD Sbjct: 121 LISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGD 180 Query: 207 SGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 SGGP++CNG LQG+VS+G C Q PGVYT + + +WI+ T+ A+ Sbjct: 181 SGGPVVCNGQLQGVVSWGDG-CAQKNKPGVYTKVYNYVKWIKNTIAAN 227 >1SPJ-A nrPDB Length = 238 Score = 304 bits (780), Expect = 2e-83, Method: Composition-based stats. Identities = 93/238 (39%), Positives = 133/238 (55%), Gaps = 15/238 (6%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 I+ G +C HSQPWQAAL + C G+LVH QWVL+AAHC ++Y + LG H+L D Sbjct: 1 IVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAAHCISDNYQLWLGRHNL-FDD 59 Query: 91 EPGSQMVEASLSVRHPEYNRPLLAN-----------DLMLIKLDESV-SESDTIRSISIA 138 E +Q V S S HP +N LL N DLML++L E + +D ++ + + Sbjct: 60 ENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKVVELP 119 Query: 139 SQCPTAGNSCLVSGWGLLANGRM--PTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGG 196 ++ P G++CL SGWG + P LQCV++ ++ + C K + M C G Sbjct: 120 TEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQKVTDFMLCVGHL 179 Query: 197 HDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 KD+C GDSGGPL+C+G LQG+ S+G PCG P V + + +WIE T+ + Sbjct: 180 EGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWIEDTIAEN 237 >2PSX-A nrPDB Length = 227 Score = 304 bits (779), Expect = 2e-83, Method: Composition-based stats. Identities = 117/227 (51%), Positives = 158/227 (69%), Gaps = 4/227 (1%) Query: 31 IINGEDCSPHSQPWQAALVME-NELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEAD 89 IING DC H+QPWQAAL++ N+L+C VLVHPQW+L+AAHC + + + LG +SL Sbjct: 1 IINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPV 60 Query: 90 QEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCL 149 E G QM + S+ HP Y+ P +NDLMLIKL+ + + +R I+++S CP+AG CL Sbjct: 61 YESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCL 120 Query: 150 VSGWGLLANGR--MPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDS 207 VSGWG + + P VLQC+N+SV+S++ C Y +MFCAG +DSC GDS Sbjct: 121 VSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD-KAGRDSCQGDS 179 Query: 208 GGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 GGP++CNG LQGLVS+G PC + PGVYTNLCKFT+WI++T+QA+ Sbjct: 180 GGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 226 >1NPM-A nrPDB Length = 225 Score = 302 bits (774), Expect = 1e-82, Method: Composition-based stats. Identities = 96/226 (42%), Positives = 140/226 (61%), Gaps = 7/226 (3%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 I+ G +C PHSQPWQAAL L C GVLV +WVL+AAHC + Y++ LG HSL++ Sbjct: 1 ILEGRECIPHSQPWQAALFQGERLICGGVLVGDRWVLTAAHCKKQKYSVRLGDHSLQSRD 60 Query: 91 EPGSQMVEASLSVRHPEYN---RPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNS 147 +P Q ++ + S++HP YN ++D+MLI+L S + D ++ + +A+ CP G Sbjct: 61 QP-EQEIQVAQSIQHPCYNNSNPEDHSHDIMLIRLQNSANLGDKVKPVQLANLCPKVGQK 119 Query: 148 CLVSGWGLLAN--GRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNG 205 C++SGWG + + P L C V + S+ C + Y M CAG + D+C G Sbjct: 120 CIISGWGTVTSPQENFPNTLNCAEVKIYSQNKCERAYPGKITEGMVCAGS-SNGADTCQG 178 Query: 206 DSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 251 DSGGPL+C+G LQG+ S+G PCG+ PGVYT +C++T WI+KT+ Sbjct: 179 DSGGPLVCDGMLQGITSWGSDPCGKPEKPGVYTKICRYTTWIKKTM 224 >5MS3-A nrPDB Length = 228 Score = 299 bits (766), Expect = 8e-82, Method: Composition-based stats. Identities = 96/229 (41%), Positives = 131/229 (57%), Gaps = 7/229 (3%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 ++ G +C PHSQPWQAAL +L C GVLV WVL+AAHC + YT+ LG HSL+ Sbjct: 1 VLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQNKD 60 Query: 91 EPGSQMVEASLSVRHPEYNR---PLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNS 147 P Q + S+ HP YN +DLML++L + S ++ IS+A C G Sbjct: 61 GP-EQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPGQK 119 Query: 148 CLVSGWGLLANGR--MPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNG 205 C VSGWG + + R P L C V + ++ C Y M CAG D+C G Sbjct: 120 CTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKG-ADTCQG 178 Query: 206 DSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 DSGGPL+C+G LQG+ S+G PCG+ PGVYTN+C++ +WI+K + + Sbjct: 179 DSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGSK 227 >3QUM-P nrPDB Length = 237 Score = 298 bits (764), Expect = 1e-81, Method: Composition-based stats. Identities = 95/237 (40%), Positives = 133/237 (56%), Gaps = 14/237 (5%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 I+ G +C HSQPWQ + C GVLVHPQWVL+AAHC +N I LG HSL Sbjct: 1 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSL-FHP 59 Query: 91 EPGSQMVEASLSVRHPEYNRPLLAN-----------DLMLIKLDESVSESDTIRSISIAS 139 E Q+ + S S HP Y+ LL N DLML++L E +D ++ + + + Sbjct: 60 EDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPT 119 Query: 140 QCPTAGNSCLVSGWGLLANGRM--PTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGH 197 Q P G +C SGWG + P LQCV++ V+S +VC++++ M CAG Sbjct: 120 QEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWT 179 Query: 198 DQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 K +C+GDSGGPL+CNG LQG+ S+G PC P +YT + + +WI+ T+ A+ Sbjct: 180 GGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 236 >3BSQ-A nrPDB Length = 227 Score = 298 bits (763), Expect = 2e-81, Method: Composition-based stats. Identities = 105/224 (46%), Positives = 144/224 (64%), Gaps = 5/224 (2%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 II+G C+ S PWQ AL+ N+L C GVLV+ +WVL+AAHC N YT+ LG +L + Sbjct: 1 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRR 60 Query: 91 EPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLV 150 +Q ++AS S RHP Y+ NDLML+KL+ S ++ + + S+C G +C V Sbjct: 61 ---AQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTV 117 Query: 151 SGWGLLANG--RMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDSG 208 SGWG + P+ L CV+V ++S + C+K+Y L SM CAG +K++CNGDSG Sbjct: 118 SGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSG 177 Query: 209 GPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 252 GPL+C G LQGLVS+G PCGQ PGVYT +CKFT+WI T++ Sbjct: 178 GPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 221 >2TLD-E nrPDB Length = 220 Score = 295 bits (757), Expect = 8e-81, Method: Composition-based stats. Identities = 89/226 (39%), Positives = 132/226 (58%), Gaps = 8/226 (3%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 I+ G C ++ P+Q +L FC G L++ QWV+SAAHC+++ + LG ++ Sbjct: 1 IVGGYTCGANTVPYQVSL-NSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVV- 58 Query: 91 EPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLV 150 E Q + AS S+ HP YN L ND+MLIKL + S + + SIS+ + C +AG CL+ Sbjct: 59 EGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLI 118 Query: 151 SGWGLLANG--RMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDSG 208 SGWG + P VL+C+ ++S+ C Y +MFCAG DSC GDSG Sbjct: 119 SGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGLEGG--DSCQGDSG 176 Query: 209 GPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 GP++C+G LQG+VS+G C PGVYT +C + WI++T+ ++ Sbjct: 177 GPVVCSGKLQGIVSWGSG-CA-KNKPGVYTKVCNYVSWIKQTIASN 220 >1AO5-A nrPDB Length = 237 Score = 295 bits (756), Expect = 1e-80, Method: Composition-based stats. Identities = 95/237 (40%), Positives = 138/237 (58%), Gaps = 14/237 (5%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 ++ G +C +SQPWQ A+ + E C GVL+ WVL+AAHC+ + Y + LG + L + Sbjct: 1 VVGGFNCEKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKL-FQE 59 Query: 91 EPGSQMVEASLSVRHPEYNRPLL-----------ANDLMLIKLDESVSESDTIRSISIAS 139 EP +Q S S HP +N LL ++DLML++L + +D ++ I++ + Sbjct: 60 EPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSDDLMLLRLSKPADITDVVKPIALPT 119 Query: 140 QCPTAGNSCLVSGWGLLANGRM--PTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGH 197 + P G+ CL SGWG + R P LQCV ++++ E C+K+Y M CAG Sbjct: 120 KEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMG 179 Query: 198 DQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 KD+C DSGGPLIC+G LQG S+G PCG+ GVP +YTNL KF WI+ T+ + Sbjct: 180 GGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 236 >6QHB-A nrPDB Length = 223 Score = 294 bits (753), Expect = 3e-80, Method: Composition-based stats. Identities = 93/223 (41%), Positives = 128/223 (57%), Gaps = 1/223 (0%) Query: 32 INGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQE 91 ++G C S P+QAAL L C GVL+HP WVL+AAHC + + + LG H+L QE Sbjct: 2 VHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNL-GQQE 60 Query: 92 PGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLVS 151 + +V HP+Y+ D+ML++L S+ I+ + + C SC + Sbjct: 61 SSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSAQTTSCHIL 120 Query: 152 GWGLLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDSGGPL 211 GWG A+G P +QC + +VS E C Y +M CAG KDSC GDSGGPL Sbjct: 121 GWGKTADGDFPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDSCQGDSGGPL 180 Query: 212 ICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 +C +L+GLVS+G PCG PGVYTN+C++T WI+KT+QA Sbjct: 181 VCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQAK 223 >1SGF-A nrPDB Length = 240 Score = 293 bits (751), Expect = 4e-80, Method: Composition-based stats. Identities = 86/232 (37%), Positives = 130/232 (56%), Gaps = 15/232 (6%) Query: 36 DCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQEPGSQ 95 DC +SQPW A+ N+ C GVL+ WVL+AAHC+ + Y + LG ++ + EP Q Sbjct: 10 DCE-NSQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHCYNDKYQVWLGKNNF-LEDEPSDQ 67 Query: 96 MVEASLSVRHPEYNR-----------PLLANDLMLIKLDESVSESDTIRSISIASQCPTA 144 S ++ HP++N +NDLML++L + +D ++ I++ ++ P Sbjct: 68 HRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEEPKL 127 Query: 145 GNSCLVSGWGLLAN--GRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDS 202 G++CL SGWG + P LQCVN+ ++ E C K ++ +M CAG + Sbjct: 128 GSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAMLCAGEMDGGSYT 187 Query: 203 CNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 C DSGGPLIC+G LQG+ S+G PCG+ P VYT L KF+ WI +T+ + Sbjct: 188 CEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRETMANN 239 >1TON-A nrPDB Length = 235 Score = 291 bits (746), Expect = 2e-79, Method: Composition-based stats. Identities = 94/237 (39%), Positives = 131/237 (55%), Gaps = 16/237 (6%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 I+ G C +SQPWQ A++ NE C GVL+ P WV++AAHC+ N+Y + LG ++L Sbjct: 1 IVGGYKCEKNSQPWQVAVI--NEYLCGGVLIDPSWVITAAHCYSNNYQVLLGRNNL-FKD 57 Query: 91 EPGSQMVEASLSVRHPEYNR-----------PLLANDLMLIKLDESVSESDTIRSISIAS 139 EP +Q S RHP+Y +NDLML+ L E + ++ I + + Sbjct: 58 EPFAQRRLVRQSFRHPDYIPLIVTNDTEQPVHDHSNDLMLLHLSEPADITGGVKVIDLPT 117 Query: 140 QCPTAGNSCLVSGWGLLANGRM--PTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGH 197 + P G++CL SGWG M LQCVN+ ++S E C + Y M CAG Sbjct: 118 KEPKVGSTCLASGWGSTNPSEMVVSHDLQCVNIHLLSNEKCIETYKDNVTDVMLCAGEME 177 Query: 198 DQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 KD+C GDSGGPLIC+G LQG+ S G PC + P +Y L KFT WI+K ++ + Sbjct: 178 GGKDTCAGDSGGPLICDGVLQGITSGGATPCAKPKTPAIYAKLIKFTSWIKKVMKEN 234 >5ZFH-A nrPDB Length = 224 Score = 290 bits (742), Expect = 5e-79, Method: Composition-based stats. Identities = 96/225 (42%), Positives = 133/225 (59%), Gaps = 5/225 (2%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 II+G C S PWQ AL+ N+L C GVLV WVL+AAHC Y + LG + Sbjct: 1 IIDGYKCKEGSHPWQVALLKGNQLHCGGVLVDKYWVLTAAHCKMGQYQVQLGSDKIG--- 57 Query: 91 EPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLV 150 + +Q ++A+ S RHP Y+ ND+ML++LDE V S + ++ + C G SC V Sbjct: 58 DQSAQKIKATKSFRHPGYSTKTHVNDIMLVRLDEPVKMSSKVEAVQLPEHCEPPGTSCTV 117 Query: 151 SGWGLLANG--RMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDSG 208 SGWG + P+ L C +V ++S C K+Y L +M CAG + ++CNGDSG Sbjct: 118 SGWGTTTSPDVTFPSDLMCSDVKLISSRECKKVYKDLLGKTMLCAGIPDSKTNTCNGDSG 177 Query: 209 GPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQA 253 GPL+CN LQGLVS+G PCGQ PGVYT +CK+ W+ +T++ Sbjct: 178 GPLVCNDTLQGLVSWGTYPCGQPNDPGVYTQVCKYKRWVMETMKT 222 >4GSO-A nrPDB Length = 232 Score = 289 bits (740), Expect = 8e-79, Method: Composition-based stats. Identities = 82/226 (36%), Positives = 126/226 (55%), Gaps = 3/226 (1%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 ++ G++C + P+ A L FC L++ +WV++AAHC ++ + LG+HS + Sbjct: 1 VLGGDECDINEHPFLAFLYSHG-YFCGLTLINQEWVVTAAHCDSTNFQMQLGVHSKKVLN 59 Query: 91 EPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLV 150 E + + +L D+MLIKLD+ +S S I +S+ S P+ G+ C + Sbjct: 60 EDEQTRNPKEKFICPNKNMSEVLDKDIMLIKLDKPISNSKHIAPLSLPSNPPSVGSVCRI 119 Query: 151 SGWGLLA--NGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDSG 208 GWG + N P V C N+++V EVC Y+ L + CAG KD+C GDSG Sbjct: 120 MGWGSITIPNETYPDVPYCANINLVDYEVCQGAYNGLPAKTTLCAGVLEGGKDTCVGDSG 179 Query: 209 GPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 GPLICNG QG+VS+G CGQ PG+YTN+ +T+WI++ + + Sbjct: 180 GPLICNGQFQGIVSYGAHSCGQGPKPGIYTNVFDYTDWIQRNIAGN 225 >2EEK-A nrPDB Length = 220 Score = 288 bits (739), Expect = 1e-78, Method: Composition-based stats. Identities = 83/223 (37%), Positives = 127/223 (56%), Gaps = 4/223 (1%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 I+ G +C+ HSQ Q +L FC G LV WV+SAAHC+++ + LG H + Sbjct: 1 IVGGYECTKHSQAHQVSL-NSGYHFCGGSLVSKDWVVSAAHCYKSVLRVRLGEHHIRV-N 58 Query: 91 EPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLV 150 E Q + +S +RHP Y+ + ND+MLIKL + + + + ++++ ++C C V Sbjct: 59 EGTEQYISSSSVIRHPNYSSYNINNDIMLIKLTKPATLNQYVHAVALPTECAADATMCTV 118 Query: 151 SGWGLL-ANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDSGG 209 SGWG ++ LQC+++ ++S C+ Y + SMFCAG KDSC GDSGG Sbjct: 119 SGWGNTMSSVADGDKLQCLSLPILSHADCANSYPGMITQSMFCAGYLEGGKDSCQGDSGG 178 Query: 210 PLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 252 P++CNG LQG+VS+G C + PGVY +C + W+ T+ Sbjct: 179 PVVCNGVLQGVVSWGYG-CAERDHPGVYAKVCVLSGWVRDTMA 220 >1EUF-A nrPDB Length = 227 Score = 285 bits (731), Expect = 8e-78, Method: Composition-based stats. Identities = 82/229 (35%), Positives = 120/229 (52%), Gaps = 10/229 (4%) Query: 31 IINGEDCSPHSQPWQAALVMENE---LFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLE 87 II G + PHS+P+ A L+ + C G LV +VL+AAHC +S + LG H++ Sbjct: 1 IIGGHEAKPHSRPYMAFLLFKTSGKSHICGGFLVREDFVLTAAHCLGSSINVTLGAHNI- 59 Query: 88 ADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPT--AG 145 ++E Q++ + HP+YN LAND+ML+KL +D + I++ G Sbjct: 60 MERERTQQVIPVRRPIPHPDYNDETLANDIMLLKLTRKADITDKVSPINLPRSLAEVKPG 119 Query: 146 NSCLVSGWGLLANGRMP-TVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCN 204 C V+GWG L LQ V++ V SEE C + + CAG +K+S + Sbjct: 120 MMCSVAGWGRLGVNMPSTDKLQEVDLEVQSEEKCIARFKNYIPFTQICAGDPSKRKNSFS 179 Query: 205 GDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQA 253 GDSGGPL+CNG QG+VS+G+ P VYT + F WI T++ Sbjct: 180 GDSGGPLVCNGVAQGIVSYGR---NDGTTPDVYTRISSFLSWIHSTMRR 225 >2AIQ-A nrPDB Length = 231 Score = 282 bits (722), Expect = 1e-76, Method: Composition-based stats. Identities = 77/226 (34%), Positives = 120/226 (53%), Gaps = 4/226 (1%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 +I G++C+ + + A LV N C G L++ +WVL+A HC + + I LG+H+L+ Sbjct: 1 VIGGDECNINEHRFLA-LVYANGSLCGGTLINQEWVLTARHCDRGNMRIYLGMHNLKVLN 59 Query: 91 EPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLV 150 + + N + D+MLI+L+ V S I +S+ S P+ G+ C + Sbjct: 60 KDALRRFPKEKYFCLNTRNDTIWDKDIMLIRLNRPVRNSAHIAPLSLPSNPPSVGSVCRI 119 Query: 151 SGWGLLA--NGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDSG 208 GWG + N +P V C N++++ VC Y + CAG KD+C GDSG Sbjct: 120 MGWGTITSPNATLPDVPHCANINILDYAVCQAAYKG-LAATTLCAGILEGGKDTCKGDSG 178 Query: 209 GPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 GPLICNG QG++S G PC Q PG+YT + +T+WI+ + + Sbjct: 179 GPLICNGQFQGILSVGGNPCAQPRKPGIYTKVFDYTDWIQSIISGN 224 >4E7N-A nrPDB Length = 238 Score = 282 bits (721), Expect = 1e-76, Method: Composition-based stats. Identities = 83/231 (35%), Positives = 117/231 (50%), Gaps = 7/231 (3%) Query: 31 IINGEDCSPHSQPWQAALVMENE--LFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEA 88 II G++C+ + + AL LFC G L++ +WVL+AAHC + ++ I LG+HS + Sbjct: 1 IIGGDECNINEHRFLVALYTSRSRTLFCGGTLINQEWVLTAAHCDRKNFRIKLGMHSKKV 60 Query: 89 DQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSC 148 E V N L D+MLI+LD V S I S+ S P+ G+ C Sbjct: 61 PNEDEQTRVPKEKFFCLSSKNYTLWDKDIMLIRLDSPVKNSKHIAPFSLPSSPPSVGSVC 120 Query: 149 LVSGWGLLAN--GRMPTVLQCVNVSVVSEEVCSKLYDPL---YHPSMFCAGGGHDQKDSC 203 + GWG ++ G P V CVN++++ E+C Y CAG KD+C Sbjct: 121 RIMGWGRISPTEGTYPDVPHCVNINLLEYEMCRAPYPEFELPATSRTLCAGILEGGKDTC 180 Query: 204 NGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 GDSGGPLICNG QG+ S+G PC Q P YT + +WIE + + Sbjct: 181 KGDSGGPLICNGQFQGIASWGDDPCAQPHKPAAYTKVFDHLDWIENIIAGN 231 >1FI8-A nrPDB Length = 228 Score = 281 bits (719), Expect = 2e-76, Method: Composition-based stats. Identities = 72/232 (31%), Positives = 117/232 (50%), Gaps = 12/232 (5%) Query: 31 IINGEDCSPHSQPWQAALV----MENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSL 86 II G + PHS+P+ A L C G L+ +VL+AAHC + + LG H++ Sbjct: 1 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKIQVTLGAHNI 60 Query: 87 EADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQC--PTA 144 + +QE Q++ + HP YN ++ND+ML+KL S ++ +++ + Sbjct: 61 K-EQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKP 119 Query: 145 GNSCLVSGWGLLAN-GRMPTVLQCVNVSVVSEEVCSKLYDPLYHP-SMFCAGGGHDQKDS 202 G+ C V+GWG L G+ LQ V ++V ++ C + + CAG ++ S Sbjct: 120 GDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRAS 179 Query: 203 CNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 GDSGGPL+C G+VS+G+ P +T + F WI+KT++ S Sbjct: 180 FRGDSGGPLVCKKVAAGIVSYGQ---NDGSTPRAFTKVSTFLSWIKKTMKKS 228 >6I44-A nrPDB Length = 627 Score = 278 bits (712), Expect = 2e-75, Method: Composition-based stats. Identities = 81/262 (30%), Positives = 127/262 (48%), Gaps = 18/262 (6%) Query: 9 GWFLGYLILGVAGSLVSGSCSQIINGEDCSPHSQPWQAALVME---NELFCSGVLVHPQW 65 G+ L G + + ++I+ G S PWQ +L ++ C G L+ QW Sbjct: 358 GYSLRLCNTGDNSVCTTKTSTRIVGGTQSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQW 417 Query: 66 VLSAAHCF-----QNSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLI 120 VL+AAHCF Q+ + I G+ L D + + + H Y +D+ LI Sbjct: 418 VLTAAHCFDGLPLQDVWRIYSGILQLS-DITKDTPFSQIKEIIIHQNYKVSEGNHDIALI 476 Query: 121 KLDESVSESDTIRSISIASQCPTAG--NSCLVSGWG-LLANGRMPTVLQCVNVSVVSEEV 177 KL + ++ + I + S+ T+ +C V+GWG G + +LQ VN+ +V+ E Sbjct: 477 KLQAPLQYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSAEAGEIQNILQKVNIPLVTNEE 536 Query: 178 CSKLY-DPLYHPSMFCAGGGHDQKDSCNGDSGGPLICN----GYLQGLVSFGKAPCGQVG 232 C K Y D M CAG KD+C GD+GGPL+C L G+ S+G+ C + Sbjct: 537 CQKRYQDYKITQRMVCAGYKEGGKDACKGDAGGPLVCKHNGMWRLVGITSWGEG-CARRE 595 Query: 233 VPGVYTNLCKFTEWIEKTVQAS 254 PGVYT + ++ +WI + Q+S Sbjct: 596 QPGVYTKVAEYMDWILEKTQSS 617 >5TJX-A nrPDB Length = 263 Score = 278 bits (711), Expect = 2e-75, Method: Composition-based stats. Identities = 80/247 (32%), Positives = 125/247 (50%), Gaps = 18/247 (7%) Query: 24 VSGSCSQIINGEDCSPHSQPWQAALVME---NELFCSGVLVHPQWVLSAAHCF-----QN 75 + + ++I+ G + S PWQ +L ++ C G L+ QWVL+AAHCF Q+ Sbjct: 9 TTKTSTRIVGGTESSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQD 68 Query: 76 SYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSI 135 + I G+ L D + + + H Y +D+ LIKL + ++ + I Sbjct: 69 VWRIYSGILELS-DITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLEYTEFQKPI 127 Query: 136 SIASQCPTAG--NSCLVSGWG-LLANGRMPTVLQCVNVSVVSEEVCSKLY-DPLYHPSMF 191 S+ S+ T+ +C V+GWG G + +LQ VN+ +V+ E C K Y D M Sbjct: 128 SLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMV 187 Query: 192 CAGGGHDQKDSCNGDSGGPLICN----GYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWI 247 CAG KD+C GDSGGPL+C L G+ S+G+ C + PGVYT + ++ +WI Sbjct: 188 CAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEG-CARREQPGVYTKVAEYMDWI 246 Query: 248 EKTVQAS 254 + Q+S Sbjct: 247 LEKTQSS 253 >1GVZ-A nrPDB Length = 237 Score = 276 bits (707), Expect = 6e-75, Method: Composition-based stats. Identities = 84/237 (35%), Positives = 129/237 (54%), Gaps = 14/237 (5%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 II G +C HS+PWQ A+ + C GVLVHPQWVL+AAHC + Y I LG H+L D Sbjct: 1 IIGGWECEKHSKPWQVAVYHQGHFQCGGVLVHPQWVLTAAHCMSDDYQIWLGRHNLSKD- 59 Query: 91 EPGSQMVEASLSVRHPEYN-----------RPLLANDLMLIKLDESVSESDTIRSISIAS 139 E +Q + S S P+++ +++DLML++L + +D ++ + + + Sbjct: 60 EDTAQFHQVSDSFLDPQFDLSLLKKKYLRPYDDISHDLMLLRLAQPARITDAVKILDLPT 119 Query: 140 QCPTAGNSCLVSGWGLLAN--GRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGH 197 Q P G++C SGWGL++ R LQCV + + S E C++ Y + CA Sbjct: 120 QEPKLGSTCYTSGWGLISTFTNRGSGTLQCVELRLQSNEKCARAYPEKMTEFVLCATHRD 179 Query: 198 DQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 D C GDSGG LIC+G QG+ S+G + C V+T + +WI++T++ + Sbjct: 180 DSGSICLGDSGGALICDGVFQGITSWGYSECADFNDNFVFTKVMPHKKWIKETIEKN 236 >1OP0-A nrPDB Length = 234 Score = 276 bits (706), Expect = 7e-75, Method: Composition-based stats. Identities = 82/227 (36%), Positives = 123/227 (54%), Gaps = 3/227 (1%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 +I G +C + + A FC G L++P+WV++AAHC + + LG+HS + Sbjct: 1 VIGGNECDINEHRFLVAFFNTTGFFCGGTLINPEWVVTAAHCDSTDFQMQLGVHSKKVLN 60 Query: 91 EPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLV 150 E + + N +L D+MLIKLD+ +S S I +S+ S P+ G+ C + Sbjct: 61 EDEQTRNPKEKFICPNKNNNEVLDKDIMLIKLDKPISNSKHIAPLSLPSSPPSVGSVCRI 120 Query: 151 SGWGLLANGR--MPTVLQCVNVSVVSEEVCSKLYDPLYHP-SMFCAGGGHDQKDSCNGDS 207 GWG + + P V C N++++ VC Y L CAG KD+C GDS Sbjct: 121 MGWGSITPVKETFPDVPYCANINLLDHAVCQAGYPELLAEYRTLCAGIVQGGKDTCGGDS 180 Query: 208 GGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 GGPLICNG QG+VS+G PCGQ PG+YTN+ +T+WI++ + + Sbjct: 181 GGPLICNGQFQGIVSYGAHPCGQGPKPGIYTNVFDYTDWIQRNIAGN 227 >3S9B-A nrPDB Length = 234 Score = 275 bits (704), Expect = 1e-74, Method: Composition-based stats. Identities = 76/227 (33%), Positives = 118/227 (51%), Gaps = 3/227 (1%) Query: 31 IINGEDCSPHSQPWQAALVME--NELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEA 88 ++ G++C+ + P+ AL + + C+G L++ +WVL+AAHC + + I LG+HS Sbjct: 1 VVGGDECNINEHPFLVALYTSASSTIHCAGALINREWVLTAAHCDRRNIRIKLGMHSKNI 60 Query: 89 DQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSC 148 E V L D+MLI+L V+ S I +S+ S+ G+ C Sbjct: 61 RNEDEQIRVPRGKYFCLNTKFPNGLDKDIMLIRLRRPVTYSTHIAPVSLPSRSRGVGSRC 120 Query: 149 LVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPS-MFCAGGGHDQKDSCNGDS 207 + GWG ++ P V C N+ +V + C LY + S CAG +D+C+GDS Sbjct: 121 RIMGWGKISTTTYPDVPHCTNIFIVKHKWCEPLYPWVPADSRTLCAGILKGGRDTCHGDS 180 Query: 208 GGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 GGPLICNG + G+V+ G PCGQ P VYT + + WI+ + + Sbjct: 181 GGPLICNGEMHGIVAGGSEPCGQHLKPAVYTKVFDYNNWIQSIIAGN 227 >3W94-A nrPDB Length = 235 Score = 274 bits (702), Expect = 2e-74, Method: Composition-based stats. Identities = 70/236 (29%), Positives = 112/236 (47%), Gaps = 15/236 (6%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNS------YTIGLGLH 84 ++ G + + PW +L C L+ W+L+AAHC ++ LGLH Sbjct: 1 VVGGVNAEKGAWPWMVSLHWRGRHGCGASLIGRDWLLTAAHCVYGKNTHLQYWSAVLGLH 60 Query: 85 SLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQC--P 142 + + Q+ + + + YNR D+ ++ L + V+ ++ + + +AS+ Sbjct: 61 AQSSMNSQEVQIRQVDRIIINKNYNRRTKEADIAMMHLQQPVNFTEWVLPVCLASEDQHF 120 Query: 143 TAGNSCLVSGWGL-LANGRMPTVLQCVNVSVVSEEVCSKLYDPL-YHPSMFCAGGGHDQK 200 AG C ++GWG G +P +LQ V +V ++ C +L + SM CAG Sbjct: 121 PAGRRCFIAGWGRDAEGGSLPDILQEAEVPLVDQDECQRLLPEYTFTSSMLCAGYPEGGV 180 Query: 201 DSCNGDSGGPLIC----NGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 252 DSC GDSGGPL+C L G+ SFG CG+ PG Y + FT WI +T + Sbjct: 181 DSCQGDSGGPLMCLEDARWTLIGVTSFGVG-CGRPERPGAYARVSAFTSWIAETRR 235 >4DGJ-A nrPDB Length = 235 Score = 274 bits (701), Expect = 3e-74, Method: Composition-based stats. Identities = 78/233 (33%), Positives = 113/233 (48%), Gaps = 15/233 (6%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQ------NSYTIGLGLH 84 I+ G D + PW L ++ L C LV W++SAAHC + +T LGLH Sbjct: 1 IVGGSDAKEGAWPWVVGLYYDDRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLH 60 Query: 85 SLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIA--SQCP 142 P + V +P YNR ND+ ++ L+ V+ +D I+ IS+ +Q Sbjct: 61 MKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPISLPEENQVF 120 Query: 143 TAGNSCLVSGWGL-LANGRMPTVLQCVNVSVVSEEVCSKLYDPL-YHPSMFCAGGGHDQK 200 G +C ++GWG + G +LQ +V ++S E C + +M CAG Sbjct: 121 PPGRNCSIAGWGTVVYQGTTADILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGI 180 Query: 201 DSCNGDSGGPLICN----GYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEK 249 DSC GDSGGPL+C +L G+ SFG C PGVY + +FTEWI+ Sbjct: 181 DSCQGDSGGPLMCQENNRWFLAGVTSFGYE-CALPNRPGVYARVSRFTEWIQS 232 >1X7A-C nrPDB Length = 235 Score = 274 bits (701), Expect = 3e-74, Method: Composition-based stats. Identities = 74/234 (31%), Positives = 121/234 (51%), Gaps = 13/234 (5%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 I+ GE+ P PWQ L + + FC G +++ +WV++AAHC + I + ++ Sbjct: 1 IVGGENAKPGQFPWQVLLNGKIDAFCGGSIINEKWVVTAAHCIEPGVKITVVAGEYNTEE 60 Query: 91 -EPGSQMVEASLSVRHPEYNRPL--LANDLMLIKLDESVSESDTIRSISIASQCPTA--- 144 EP Q ++ H YN + ++D+ L++LDE ++ + + I IA + T Sbjct: 61 TEPTEQRRNVIRAIPHHSYNATVNKYSHDIALLELDEPLTLNSYVTPICIADKEYTNIFL 120 Query: 145 -GNSCLVSGWGLLAN-GRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDS 202 S VSGWG + N GR T+LQ + V +V C + + +MFCAG KDS Sbjct: 121 KFGSGYVSGWGRVFNRGRSATILQYLKVPLVDRATCLRSTKFTIYSNMFCAGFHEGGKDS 180 Query: 203 CNGDSGGPLICN----GYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 252 C GDSGGP + +L G++S+G+ C G G+YT + ++ WI++ + Sbjct: 181 CQGDSGGPHVTEVEGTSFLTGIISWGEE-CAVKGKYGIYTKVSRYVNWIKEKTK 233 >3S69-A nrPDB Length = 234 Score = 272 bits (697), Expect = 8e-74, Method: Composition-based stats. Identities = 83/227 (36%), Positives = 121/227 (53%), Gaps = 3/227 (1%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 +I G++C+ + A FCSG L++ +WVL+AAHC ++ + LG+HS + Sbjct: 1 VIGGDECNINEHRSLVAFFNSTGFFCSGTLINEEWVLTAAHCDNTNFQMKLGVHSKKVLN 60 Query: 91 EPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLV 150 E + + N +L D+MLIKLD VS S+ I +S+ S P+ G+ C + Sbjct: 61 EDEQTRNPKEKFICPNKKNDEVLDKDIMLIKLDSRVSNSEHIVPLSLPSSPPSVGSVCHI 120 Query: 151 SGWGLLANGR--MPTVLQCVNVSVVSEEVCSKLYDPLYHP-SMFCAGGGHDQKDSCNGDS 207 GWG + + P V C ++++ + VC Y L CAG KD+C GDS Sbjct: 121 MGWGSITPIKVTYPDVPYCAYINLLDDAVCQAGYPELLTEYRTLCAGILEGGKDTCGGDS 180 Query: 208 GGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 GGPLICNG QG+VSFG PCGQ PGVYT + + WI+ + + Sbjct: 181 GGPLICNGQFQGIVSFGAHPCGQGLKPGVYTKVFDYNHWIQSIIAGN 227 >2F83-A nrPDB Length = 625 Score = 272 bits (696), Expect = 9e-74, Method: Composition-based stats. Identities = 73/246 (29%), Positives = 112/246 (45%), Gaps = 18/246 (7%) Query: 24 VSGSCSQIINGEDCSPHSQPWQAALVMEN---ELFCSGVLVHPQWVLSAAHCFQNS---- 76 + +I+ G PWQ L + C G ++ QW+L+AAHCF Sbjct: 381 TTKIKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPK 440 Query: 77 -YTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSI 135 + G+ + +E S + H +Y D+ L+KL+ +V+ +D+ R I Sbjct: 441 ILRVYSGILNQSEIKEDTS-FFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPI 499 Query: 136 SIASQCPTA--GNSCLVSGWGLLA-NGRMPTVLQCVNVSVVSEEVCSKLYDP-LYHPSMF 191 + S+ C V+GWG ++ LQ + +V+ E C K Y M Sbjct: 500 CLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMI 559 Query: 192 CAGGGHDQKDSCNGDSGGPLICN----GYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWI 247 CAG KD+C GDSGGPL C +L G+ S+G+ C Q PGVYTN+ ++ +WI Sbjct: 560 CAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEG-CAQRERPGVYTNVVEYVDWI 618 Query: 248 EKTVQA 253 + QA Sbjct: 619 LEKTQA 624 >1NN6-A nrPDB Length = 228 Score = 272 bits (696), Expect = 1e-73, Method: Composition-based stats. Identities = 81/232 (34%), Positives = 121/232 (52%), Gaps = 12/232 (5%) Query: 30 QIINGEDCSPHSQPWQAAL--VMENEL--FCSGVLVHPQWVLSAAHCFQNSYTIGLGLHS 85 +II G +C PHS+P+ A L V N FC G L+ +VL+AAHC S T+ LG H+ Sbjct: 2 EIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHN 61 Query: 86 LEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQ--CPT 143 + ++E Q +E RHP+YN L +D+ML+KL E S + + ++ SQ Sbjct: 62 I-TEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVP 120 Query: 144 AGNSCLVSGWGLLANGRM-PTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDS 202 G C V+GWG + LQ V + ++ + CS + H C G K + Sbjct: 121 PGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACS-HFRDFDHNLQLCVGNPRKTKSA 179 Query: 203 CNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 GDSGGPL+C G QG+VS+G++ P V+T + + WI + +QA+ Sbjct: 180 FKGDSGGPLLCAGVAQGIVSYGRS---DAKPPAVFTRISHYRPWINQILQAN 228 >1IAU-A nrPDB Length = 227 Score = 271 bits (693), Expect = 2e-73, Method: Composition-based stats. Identities = 75/230 (32%), Positives = 120/230 (52%), Gaps = 11/230 (4%) Query: 31 IINGEDCSPHSQPWQAALVMENEL---FCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLE 87 II G + PHS+P+ A L++ ++ C G L+ +VL+AAHC+ +S + LG H+++ Sbjct: 1 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 60 Query: 88 ADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPT--AG 145 +QEP Q + + HP YN +ND+ML++L+ + ++ + + S G Sbjct: 61 -EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPG 119 Query: 146 NSCLVSGWGLLAN-GRMPTVLQCVNVSVVSEEVCSKLYDPLYHPS-MFCAGGGHDQKDSC 203 +C V+GWG A G+ LQ V ++V + C Y + C G +K S Sbjct: 120 QTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSF 179 Query: 204 NGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQA 253 GDSGGPL+CN QG+VS+G+ P T + F WI+KT++ Sbjct: 180 KGDSGGPLVCNKVAQGIVSYGR---NNGMPPRACTKVSSFVHWIKKTMKR 226 >1BQY-A nrPDB Length = 234 Score = 270 bits (692), Expect = 3e-73, Method: Composition-based stats. Identities = 77/227 (33%), Positives = 116/227 (51%), Gaps = 3/227 (1%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 + G++C+ + L N C G L++ WV++AAHC N++ + G+HS + Sbjct: 1 VFGGDECNINEHRSLVVLFNSNGFLCGGTLINQDWVVTAAHCDSNNFQLLFGVHSKKILN 60 Query: 91 EPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLV 150 E + D+MLIKLD SVS S+ I +S+ S P+ G+ C + Sbjct: 61 EDEQTRDPKEKFFCPNRKKDDEVDKDIMLIKLDSSVSNSEHIAPLSLPSSPPSVGSVCRI 120 Query: 151 SGWGLLANGR--MPTVLQCVNVSVVSEEVCSKLYDPL-YHPSMFCAGGGHDQKDSCNGDS 207 GWG + P V C N++++ VC Y + CAG +D+C+ DS Sbjct: 121 MGWGKTIPTKEIYPDVPHCANINILDHAVCRTAYSWRQVANTTLCAGILQGGRDTCHFDS 180 Query: 208 GGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 GGPLICNG QG+VS+G PCGQ G PGVYT + + +WI+ + + Sbjct: 181 GGPLICNGIFQGIVSWGGHPCGQPGEPGVYTKVFDYLDWIKSIIAGN 227 >3LC3-A nrPDB Length = 235 Score = 270 bits (692), Expect = 3e-73, Method: Composition-based stats. Identities = 74/235 (31%), Positives = 119/235 (50%), Gaps = 15/235 (6%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQN--SYTIGLGLHSLEA 88 ++ GED P PWQ L + + FC G +V+ +W+++AAHC + T+ G H++E Sbjct: 1 VVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCVETGVKITVVAGEHNIE- 59 Query: 89 DQEPGSQMVEASLSVRHPEYNRPL--LANDLMLIKLDESVSESDTIRSISIASQCPTA-- 144 + E Q + H YN + +D+ L++LDE + + + I IA + T Sbjct: 60 ETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEYTNIF 119 Query: 145 --GNSCLVSGWGLL-ANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKD 201 S VSGWG + GR VLQ + V +V C + + +MFCAG +D Sbjct: 120 LKFGSGYVSGWGRVFHKGRSALVLQYLRVPLVDRATCLRSTKFTIYNNMFCAGFHEGGRD 179 Query: 202 SCNGDSGGPLICN----GYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 252 SC GDSGGP + +L G++S+G+ C G G+YT + ++ WI++ + Sbjct: 180 SCQGDSGGPHVTEVEGTSFLTGIISWGEE-CAMKGKYGIYTKVSRYVNWIKEKTK 233 >5GVT-A nrPDB Length = 250 Score = 269 bits (689), Expect = 8e-73, Method: Composition-based stats. Identities = 76/240 (31%), Positives = 116/240 (48%), Gaps = 18/240 (7%) Query: 31 IINGEDCSPHSQPWQAALVME---NELFCSGVLVHPQWVLSAAHCFQ-----NSYTIGLG 82 I+ G + S PWQ +L ++ C G ++ QWVL+AAHCF + + I G Sbjct: 1 IVGGTNASLGEWPWQVSLQVKLVSQTHLCGGSIIGRQWVLTAAHCFDGIPYPDVWRIYGG 60 Query: 83 LHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCP 142 + SL + + H EY D+ LIKL ++ ++ + IS+ S+ Sbjct: 61 ILSLSEITKETPSSR-IKELIIHQEYKVSEGNYDIALIKLQTPLNYTEFQKPISLPSKAD 119 Query: 143 TAG--NSCLVSGWGLLAN-GRMPTVLQCVNVSVVSEEVCSKLY-DPLYHPSMFCAGGGHD 198 T +C V+GWG G +LQ + +V E C K Y D + + M CAG Sbjct: 120 TNTIYTNCWVTGWGYTKEQGETQNILQKATIPLVPNEECQKKYRDYVINKQMICAGYKEG 179 Query: 199 QKDSCNGDSGGPLICN----GYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 D+C GDSGGPL+C L G+ S+G+ C + PGVYT + ++ +WI + Q+S Sbjct: 180 GTDACKGDSGGPLVCKHSGRWQLVGITSWGEG-CARKDQPGVYTKVSEYMDWILEKTQSS 238 >1EKB-B nrPDB Length = 235 Score = 267 bits (684), Expect = 3e-72, Method: Composition-based stats. Identities = 77/233 (33%), Positives = 111/233 (47%), Gaps = 15/233 (6%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQ------NSYTIGLGLH 84 I+ G D + PW AL +++ C LV W++SAAHC + + LGLH Sbjct: 1 IVGGSDSREGAWPWVVALYFDDQQVCGASLVSRDWLVSAAHCVYGRNMEPSKWKAVLGLH 60 Query: 85 SLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIA--SQCP 142 P + V +P YN+ ND+ ++ L+ V+ +D I+ I + +Q Sbjct: 61 MASNLTSPQIETRLIDQIVINPHYNKRRKNNDIAMMHLEMKVNYTDYIQPICLPEENQVF 120 Query: 143 TAGNSCLVSGWG-LLANGRMPTVLQCVNVSVVSEEVCSKLYDPL-YHPSMFCAGGGHDQK 200 G C ++GWG L+ G VLQ +V ++S E C + +M CAG Sbjct: 121 PPGRICSIAGWGALIYQGSTADVLQEADVPLLSNEKCQQQMPEYNITENMVCAGYEAGGV 180 Query: 201 DSCNGDSGGPLICN----GYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEK 249 DSC GDSGGPL+C L G+ SFG C PGVY + +FTEWI+ Sbjct: 181 DSCQGDSGGPLMCQENNRWLLAGVTSFGY-QCALPNRPGVYARVPRFTEWIQS 232 >2CGA-A nrPDB Length = 245 Score = 267 bits (682), Expect = 4e-72, Method: Composition-based stats. Identities = 74/235 (31%), Positives = 120/235 (51%), Gaps = 12/235 (5%) Query: 29 SQIINGEDCSPHSQPWQAALVME-NELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLE 87 S+I+NGE+ P S PWQ +L + FC G L++ WV++AAHC + + + + Sbjct: 14 SRIVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGVTTSDVVVAGEFDQ 73 Query: 88 ADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIA--SQCPTAG 145 Q ++ + ++ +YN + ND+ L+KL + S S T+ ++ + S AG Sbjct: 74 GSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDDFAAG 133 Query: 146 NSCLVSGWGLL--ANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSC 203 +C+ +GWGL N P LQ ++ ++S C K + +M CAG SC Sbjct: 134 TTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKKYWGTKIKDAMICAGAS--GVSSC 191 Query: 204 NGDSGGPLICN----GYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 GDSGGPL+C L G+VS+G + C PGVY + W+++T+ A+ Sbjct: 192 MGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTS-TPGVYARVTALVNWVQQTLAAN 245 >3T2N-A nrPDB Length = 372 Score = 267 bits (682), Expect = 4e-72, Method: Composition-based stats. Identities = 76/247 (30%), Positives = 108/247 (43%), Gaps = 23/247 (9%) Query: 29 SQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLE- 87 +I+ G D S PWQ +L + C G L+ WVL+AAHCF + Sbjct: 116 DRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAG 175 Query: 88 --ADQEPGSQMVEASLSVRHPEY------NRPLLANDLMLIKLDESVSESDTIRSISIAS 139 A P + V H Y N +ND+ L+ L + ++ I+ + + + Sbjct: 176 AVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPA 235 Query: 140 --QCPTAGNSCLVSGWGLLA-NGRMPTVLQCVNVSVVSEEVCS--KLYDPLYHPSMFCAG 194 Q G C V+GWG G+ VLQ V ++S +VC+ Y P MFCAG Sbjct: 236 AGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAG 295 Query: 195 GGHDQKDSCNGDSGGPLICN--------GYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEW 246 D+C GDSGGP +C L G+VS+G C PGVYT + F EW Sbjct: 296 YPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTG-CALAQKPGVYTKVSDFREW 354 Query: 247 IEKTVQA 253 I + ++ Sbjct: 355 IFQAIKT 361 >1KIG-H nrPDB Length = 241 Score = 267 bits (682), Expect = 5e-72, Method: Composition-based stats. Identities = 69/236 (29%), Positives = 115/236 (48%), Gaps = 13/236 (5%) Query: 31 IINGEDCSPHSQPWQAALVME-NELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEAD 89 I+ G DC+ PWQA LV E NE FC G +++ +VL+AAHC + + + + Sbjct: 1 IVGGRDCAEGECPWQALLVNEENEGFCGGTILNEFYVLTAAHCLHQAKRFTVRVGDRNTE 60 Query: 90 QEPG-SQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQC-----PT 143 QE G E ++V+H + + D+ +++L + + + + Sbjct: 61 QEEGNEMAHEVEMTVKHSRFVKETYDFDIAVLRLKTPIRFRRNVAPACLPEKDWAEATLM 120 Query: 144 AGNSCLVSGWGLL-ANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDS 202 + +VSG+G GR+ + L+ + V V C P+MFCAG +D+ Sbjct: 121 TQKTGIVSGFGRTHEKGRLSSTLKMLEVPYVDRSTCKLSSSFTITPNMFCAGYDTQPEDA 180 Query: 203 CNGDSGGPLICNG----YLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 C GDSGGP + ++ G+VS+G+ C + G GVYT + F +WI+K ++A Sbjct: 181 CQGDSGGPHVTRFKDTYFVTGIVSWGEG-CARKGKFGVYTKVSNFLKWIDKIMKAR 235 >3TK9-A nrPDB Length = 226 Score = 266 bits (681), Expect = 6e-72, Method: Composition-based stats. Identities = 72/229 (31%), Positives = 119/229 (51%), Gaps = 10/229 (4%) Query: 31 IINGEDCSPHSQPWQAA---LVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLE 87 II G + PHS+P+ A L ++ C G+LV +VL+AAHC +S + LG H+++ Sbjct: 1 IIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAHCQGSSINVTLGAHNIK 60 Query: 88 ADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPT--AG 145 +QE Q + + HP YN +N++ML++L+ + +R + + S G Sbjct: 61 -EQERTQQFIPVKRPIPHPAYNPKNFSNNIMLLQLERKAKWTTAVRPLRLPSSKAQVKPG 119 Query: 146 NSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYDPLY-HPSMFCAGGGHDQKDSCN 204 C V+GWG ++ + T LQ V ++V + C +L+ Y + C G + Sbjct: 120 QLCSVAGWGYVSMSTLATTLQEVLLTVQKDCQCERLFHGNYSRATEICVGDPKKTQTGFK 179 Query: 205 GDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQA 253 GDSGGPL+C QG++S+G + PGVY + F WI++T++ Sbjct: 180 GDSGGPLVCKDVAQGILSYGNK---KGTPPGVYIKVSHFLPWIKRTMKR 225 >3K65-B nrPDB Length = 308 Score = 265 bits (678), Expect = 1e-71, Method: Composition-based stats. Identities = 79/263 (30%), Positives = 118/263 (44%), Gaps = 35/263 (13%) Query: 23 LVSGSCSQIINGEDCSPHSQPWQAALVMEN--ELFCSGVLVHPQWVLSAAHCF------- 73 L S +I+ G D PWQ L ++ EL C L+ +WVL+AAHC Sbjct: 42 LESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDK 101 Query: 74 ---QNSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYN-RPLLANDLMLIKLDESVSES 129 +N + +G HS + ++ HP YN R L D+ L+KL + V+ S Sbjct: 102 NFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFS 161 Query: 130 DTIRSISIASQCP-----TAGNSCLVSGWGLLANG-------RMPTVLQCVNVSVVSEEV 177 D I + + + AG V+GWG L P+VLQ VN+ +V V Sbjct: 162 DYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPV 221 Query: 178 CSKLYDPLYHPSMFCAGG---GHDQKDSCNGDSGGPLICN------GYLQGLVSFGKAPC 228 C +MFCAG + D+C GD+GGP + Y G+VS+G+ C Sbjct: 222 CKDSTRIRITDNMFCAGYKPDEGKRGDACEGDAGGPFVMKSPFNNRWYQMGIVSWGEG-C 280 Query: 229 GQVGVPGVYTNLCKFTEWIEKTV 251 + G G YT++ + +WI+K + Sbjct: 281 DRDGKYGFYTHVFRLKKWIQKVI 303 >3NXP-A nrPDB Length = 424 Score = 265 bits (677), Expect = 2e-71, Method: Composition-based stats. Identities = 80/263 (30%), Positives = 118/263 (44%), Gaps = 35/263 (13%) Query: 23 LVSGSCSQIINGEDCSPHSQPWQAALVMEN--ELFCSGVLVHPQWVLSAAHCF------- 73 L S +I+ G D PWQ L ++ EL C L+ +WVL+AAHC Sbjct: 158 LESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDK 217 Query: 74 ---QNSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYN-RPLLANDLMLIKLDESVSES 129 +N + +G HS + ++ HP YN R L D+ L+KL + V+ S Sbjct: 218 NFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFS 277 Query: 130 DTIRSISIASQCP-----TAGNSCLVSGWGLLANG-------RMPTVLQCVNVSVVSEEV 177 D I + + + AG V+GWG L P+VLQ VN+ +V V Sbjct: 278 DYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPV 337 Query: 178 CSKLYDPLYHPSMFCAGG---GHDQKDSCNGDSGGPLICN------GYLQGLVSFGKAPC 228 C +MFCAG + D+C GDSGGP + Y G+VS+G+ C Sbjct: 338 CKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEG-C 396 Query: 229 GQVGVPGVYTNLCKFTEWIEKTV 251 + G G YT++ + +WI+K + Sbjct: 397 DRDGKYGFYTHVFRLKKWIQKVI 419 >4NZQ-A nrPDB Length = 557 Score = 263 bits (673), Expect = 4e-71, Method: Composition-based stats. Identities = 80/263 (30%), Positives = 118/263 (44%), Gaps = 35/263 (13%) Query: 23 LVSGSCSQIINGEDCSPHSQPWQAALVMEN--ELFCSGVLVHPQWVLSAAHCF------- 73 L S +I+ G D PWQ L ++ EL C L+ +WVL+AAHC Sbjct: 291 LESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDK 350 Query: 74 ---QNSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYN-RPLLANDLMLIKLDESVSES 129 +N + +G HS + ++ HP YN R L D+ L+KL + V+ S Sbjct: 351 NFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFS 410 Query: 130 DTIRSISIASQCP-----TAGNSCLVSGWGLLANG-------RMPTVLQCVNVSVVSEEV 177 D I + + + AG V+GWG L P+VLQ VN+ +V V Sbjct: 411 DYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPV 470 Query: 178 CSKLYDPLYHPSMFCAGG---GHDQKDSCNGDSGGPLICN------GYLQGLVSFGKAPC 228 C +MFCAG + D+C GDSGGP + Y G+VS+G+ C Sbjct: 471 CKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEG-C 529 Query: 229 GQVGVPGVYTNLCKFTEWIEKTV 251 + G G YT++ + +WI+K + Sbjct: 530 DRDGKYGFYTHVFRLKKWIQKVI 552 >4DUR-A nrPDB Length = 791 Score = 263 bits (673), Expect = 5e-71, Method: Composition-based stats. Identities = 74/245 (30%), Positives = 111/245 (45%), Gaps = 22/245 (8%) Query: 24 VSGSCSQIINGEDCSPHSQPWQAALVME-NELFCSGVLVHPQWVLSAAHCFQ-----NSY 77 +++ G PHS PWQ +L FC G L+ P+WVL+AAHC + +SY Sbjct: 555 PKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSY 614 Query: 78 TIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISI 137 + LG H E + EP Q +E S P D+ L+KL +D + + Sbjct: 615 KVILGAHQ-EVNLEPHVQEIEVSRLFLEP------TRKDIALLKLSSPAVITDKVIPACL 667 Query: 138 ASQCPTAG--NSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSK--LYDPLYHPSMFCA 193 S C ++GWG +L+ + V+ +VC++ + + CA Sbjct: 668 PSPNYVVADRTECFITGWGETQGTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCA 727 Query: 194 GGGHDQKDSCNGDSGGPLICNG----YLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEK 249 G DSC GDSGGPL+C LQG+ S+G C + PGVY + +F WIE Sbjct: 728 GHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLG-CARPNKPGVYVRVSRFVTWIEG 786 Query: 250 TVQAS 254 ++ + Sbjct: 787 VMRNN 791 >5UGG-A nrPDB Length = 251 Score = 263 bits (673), Expect = 5e-71, Method: Composition-based stats. Identities = 74/245 (30%), Positives = 111/245 (45%), Gaps = 22/245 (8%) Query: 24 VSGSCSQIINGEDCSPHSQPWQAALVME-NELFCSGVLVHPQWVLSAAHCFQ-----NSY 77 +++ G PHS PWQ +L FC G L+ P+WVL+AAHC + +SY Sbjct: 15 PKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSY 74 Query: 78 TIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISI 137 + LG H E + EP Q +E S P D+ L+KL +D + + Sbjct: 75 KVILGAHQ-EVNLEPHVQEIEVSRLFLEP------TRKDIALLKLSSPAVITDKVIPACL 127 Query: 138 ASQCPTAG--NSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSK--LYDPLYHPSMFCA 193 S C ++GWG +L+ + V+ +VC++ + + CA Sbjct: 128 PSPNYVVADRTECFITGWGETQGTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCA 187 Query: 194 GGGHDQKDSCNGDSGGPLICNG----YLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEK 249 G DSC GDSGGPL+C LQG+ S+G C + PGVY + +F WIE Sbjct: 188 GHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLG-CARPNKPGVYVRVSRFVTWIEG 246 Query: 250 TVQAS 254 ++ + Sbjct: 247 VMRNN 251 >1MKW-K nrPDB Length = 308 Score = 263 bits (673), Expect = 5e-71, Method: Composition-based stats. Identities = 75/263 (28%), Positives = 115/263 (43%), Gaps = 35/263 (13%) Query: 23 LVSGSCSQIINGEDCSPHSQPWQAALVMEN--ELFCSGVLVHPQWVLSAAHCF------- 73 S +I+ G+D PWQ L ++ EL C L+ +WVL+AAHC Sbjct: 42 FESYIEGRIVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDK 101 Query: 74 ---QNSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYN-RPLLANDLMLIKLDESVSES 129 + + +G HS + ++ HP YN + L D+ L+KL + S Sbjct: 102 NFTVDDLLVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELS 161 Query: 130 DTIRSISIA-----SQCPTAGNSCLVSGWGLLANG-------RMPTVLQCVNVSVVSEEV 177 D I + + ++ AG V+GWG P+VLQ VN+ +V V Sbjct: 162 DYIHPVCLPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVERPV 221 Query: 178 CSKLYDPLYHPSMFCAGGGHD---QKDSCNGDSGGPLICN------GYLQGLVSFGKAPC 228 C +MFCAG + D+C GDSGGP + Y G+VS+G+ C Sbjct: 222 CKASTRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWGEG-C 280 Query: 229 GQVGVPGVYTNLCKFTEWIEKTV 251 + G G YT++ + +WI+K + Sbjct: 281 DRDGKYGFYTHVFRLKKWIQKVI 303 >2F91-A nrPDB Length = 237 Score = 262 bits (670), Expect = 1e-70, Method: Composition-based stats. Identities = 77/234 (32%), Positives = 115/234 (49%), Gaps = 17/234 (7%) Query: 31 IINGEDCSPHSQPWQAALVM----ENELFCSGVLVHPQWVLSAAHC-FQNSYTIGLGLHS 85 I+ G D + P+Q + + FC + + + ++A HC + + Y GL Sbjct: 1 IVGGTDATLGEFPYQLSFQETFIGFSFHFCGASIYNENYAITAGHCVYGDDYENPSGLQI 60 Query: 86 LEAD-----QEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQ 140 + + E Q++ S + H ++ LL ND+ L+KL S++ +D + I++ Q Sbjct: 61 VAGELDMSVNEGSEQIITVSKIILHENFDYNLLDNDISLLKLSGSLTFNDNVAPIALPEQ 120 Query: 141 CPTAGNSCLVSGWGLL-ANGRMPTVLQCVNVSVVSEEVCSKLYD-PLYHPSMFCAGGGHD 198 TA +V+GWG G P VLQ V V +VS+E C Y SM CAG Sbjct: 121 GHTATGDVIVTGWGTTSEGGNTPDVLQKVTVPLVSDEDCRADYGADEILDSMICAGVPEG 180 Query: 199 QKDSCNGDSGGPLICNG----YLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIE 248 KDSC GDSGGPL + YL G+VS+G C + G PGVYT + +WI+ Sbjct: 181 GKDSCQGDSGGPLAASDTGSTYLAGIVSWGYG-CARPGYPGVYTEVSYHVDWIK 233 >1C5M-D nrPDB Length = 255 Score = 262 bits (670), Expect = 1e-70, Method: Composition-based stats. Identities = 64/236 (27%), Positives = 116/236 (49%), Gaps = 13/236 (5%) Query: 31 IINGEDCSPHSQPWQAALVME-NELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEAD 89 I+ G++C PWQA L+ E NE FC G ++ ++L+AAHC + + + + Sbjct: 1 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTE 60 Query: 90 QEPGSQMV-EASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQC-----PT 143 QE G + V E + ++H + + D+ +++L ++ + + + Sbjct: 61 QEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLM 120 Query: 144 AGNSCLVSGWGLL-ANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDS 202 + +VSG+G GR T L+ + V V C + +MFCAG Q+D+ Sbjct: 121 TQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDA 180 Query: 203 CNGDSGGPLICNG----YLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 C GDSGGP + ++ G+VS+G+ C + G G+YT + F +WI+++++ Sbjct: 181 CQGDSGGPHVTRFKDTYFVTGIVSWGEG-CARKGKYGIYTKVTAFLKWIDRSMKTR 235 >3G01-A nrPDB Length = 227 Score = 262 bits (669), Expect = 1e-70, Method: Composition-based stats. Identities = 77/230 (33%), Positives = 126/230 (54%), Gaps = 12/230 (5%) Query: 31 IINGEDCSPHSQPWQAAL----VMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSL 86 II G + SPHS+P+ A V ++FC G LV ++VL+AAHC S T+ LG H++ Sbjct: 1 IIGGNEISPHSRPYMAYYEFLKVGGKKMFCGGFLVRDKFVLTAAHCKGRSMTVTLGAHNI 60 Query: 87 EADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCP--TA 144 +A +E Q++ + ++ HP+YN +ND+ML+KL + + +R +++ + Sbjct: 61 KAKEE-TQQIIPVAKAIPHPDYNPDDRSNDIMLLKLVRNAKRTRAVRPLNLPRRNAHVKP 119 Query: 145 GNSCLVSGWGLLAN-GRMPTVLQCVNVSVVSEEVCSKLYDPLYH-PSMFCAGGGHDQKDS 202 G+ C V+GWG + G P L V ++V ++VC + Y+ + C G + S Sbjct: 120 GDECYVAGWGKVTPDGEFPKTLHEVKLTVQKDQVCESQFQSSYNRANEICVGDSKIKGAS 179 Query: 203 CNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 252 GDSGGPL+C G+VS+G+ P V+T + F WI+KT++ Sbjct: 180 FRGDSGGPLVCKRAAAGIVSYGQT---DGSAPQVFTRVLSFVSWIKKTMK 226 >4MPW-A nrPDB Length = 245 Score = 261 bits (667), Expect = 2e-70, Method: Composition-based stats. Identities = 73/241 (30%), Positives = 113/241 (46%), Gaps = 26/241 (10%) Query: 31 IINGEDCSPHSQPWQAALVMEN---ELFCSGVLVHPQWVLSAAHCFQNSYT--IGLGLHS 85 I+ G++ PWQ +L + FC G L+HPQWVL+AAHC L + Sbjct: 1 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 60 Query: 86 LEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIA--SQCPT 143 E Q++ S + HP++ + D+ L++L+E V S + ++++ S+ Sbjct: 61 REQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVKVSSHVHTVTLPPASETFP 120 Query: 144 AGNSCLVSGWGLLANGR---MPTVLQCVNVSVVSEEVCSKLYD---------PLYHPSMF 191 G C V+GWG + N P L+ V V ++ +C Y + M Sbjct: 121 PGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDML 180 Query: 192 CAGGGHDQKDSCNGDSGGPLICN----GYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWI 247 CAG +DSC GDSGGPL+C G+VS+G+ C Q PG+YT + + +WI Sbjct: 181 CAGNTR--RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEG-CAQPNRPGIYTRVTYYLDWI 237 Query: 248 E 248 Sbjct: 238 H 238 >5LPF-A nrPDB Length = 234 Score = 261 bits (667), Expect = 2e-70, Method: Composition-based stats. Identities = 82/231 (35%), Positives = 121/231 (52%), Gaps = 13/231 (5%) Query: 34 GEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQEPG 93 G C+ SQPWQ +L C+GVLV WVL+AAHC +G L Q G Sbjct: 7 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQ--G 64 Query: 94 SQMVEASLSVRHPEYNR--------PLLANDLMLIKLDESVSESDTIRSISIASQCPTAG 145 Q+ + SV HP+Y++ +DLML+KL V +R++ + +C G Sbjct: 65 EQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPG 124 Query: 146 NSCLVSGWGLLANGR--MPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSC 203 + C V+GWG A R L C +++++S + C Y + +M CAG +D C Sbjct: 125 DQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAG-LDRGQDPC 183 Query: 204 NGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 DSGGPL+C+ LQG++S+G PCG P VYT +CK+ WI K ++++ Sbjct: 184 QSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 234 >2OQ5-A nrPDB Length = 232 Score = 260 bits (666), Expect = 3e-70, Method: Composition-based stats. Identities = 64/231 (27%), Positives = 101/231 (43%), Gaps = 11/231 (4%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 I+ G + PWQA+L + C L++ W++SAAHCF S Sbjct: 1 IVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTYKNPARWTASFGVTI 60 Query: 91 EPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIA--SQCPTAGNSC 148 +P + H +Y P D+ L +L V ++ + + + S G+ Sbjct: 61 KPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASYEFQPGDVM 120 Query: 149 LVSGWGLLANGRMP-TVLQCVNVSVVSEEVCS--KLYDPLYHPSMFCAGGGHDQKDSCNG 205 V+G+G L N L+ V+++ C+ + Y+ P M CAG + D+C G Sbjct: 121 FVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITPRMLCAGSLEGKTDACQG 180 Query: 206 DSGGPLICN-----GYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 251 DSGGPL+ + YL G+VS+G C + PGVYT + +WI Sbjct: 181 DSGGPLVSSDARDIWYLAGIVSWGDE-CAKPNKPGVYTRVTALRDWITSKT 230 >3E0N-B nrPDB Length = 271 Score = 260 bits (665), Expect = 4e-70, Method: Composition-based stats. Identities = 85/243 (34%), Positives = 115/243 (47%), Gaps = 24/243 (9%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCF-----QNSYTIGLGLHS 85 I G PWQ ++ E C G LV QWVLSAAHCF + +Y + LG H Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQ 60 Query: 86 LEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIAS--QCPT 143 L++ E +++ + HP Y + D+ L++L ++ S IR IS+ + Sbjct: 61 LDSYSED-AKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAAQASFP 119 Query: 144 AGNSCLVSGWGLLANGR---MPTVLQCVNVSVVSEEVCSKLY--------DPLYHPSMFC 192 G C V+GWG +A P LQ + V ++S E C+ LY M C Sbjct: 120 NGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNSLYNIDAKPEEPHFVQEDMVC 179 Query: 193 AGGGHDQKDSCNGDSGGPLICN----GYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIE 248 AG KD+C GDSGGPL C YL G+VS+G A CG PGVYT + WI+ Sbjct: 180 AGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDA-CGARNRPGVYTLASSYASWIQ 238 Query: 249 KTV 251 V Sbjct: 239 SKV 241 >3DFJ-A nrPDB Length = 263 Score = 259 bits (662), Expect = 9e-70, Method: Composition-based stats. Identities = 85/243 (34%), Positives = 115/243 (47%), Gaps = 24/243 (9%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCF-----QNSYTIGLGLHS 85 I G PWQ ++ E C G LV QWVLSAAHCF + +Y + LG H Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQ 60 Query: 86 LEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIAS--QCPT 143 L++ E +++ + HP Y + D+ L++L ++ S IR IS+ + Sbjct: 61 LDSYSED-AKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAANASFP 119 Query: 144 AGNSCLVSGWGLLANGR---MPTVLQCVNVSVVSEEVCSKLY--------DPLYHPSMFC 192 G C V+GWG +A P LQ + V ++S E C+ LY M C Sbjct: 120 NGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNALYNIDAKPEEPHFVQEDMVC 179 Query: 193 AGGGHDQKDSCNGDSGGPLICN----GYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIE 248 AG KD+C GDSGGPL C YL G+VS+G A CG PGVYT + WI+ Sbjct: 180 AGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDA-CGARNRPGVYTLASSYASWIQ 238 Query: 249 KTV 251 V Sbjct: 239 SKV 241 >6AOD-C nrPDB Length = 245 Score = 259 bits (662), Expect = 1e-69, Method: Composition-based stats. Identities = 73/239 (30%), Positives = 109/239 (45%), Gaps = 18/239 (7%) Query: 31 IINGEDCSPHSQPWQAALVMEN---ELFCSGVLVHPQWVLSAAHCFQNS-----YTIGLG 82 I+ G PWQ L + C G ++ QW+L+AAHCF + G Sbjct: 1 IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSG 60 Query: 83 LHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCP 142 + +E S + H +Y D+ L+KL+ +V +D+ R IS+ S+ Sbjct: 61 ILQQSEIKEDTS-FFGVQEIIIHDQYKMAESGYDIALLKLETTVQYTDSQRPISLPSKGD 119 Query: 143 TA--GNSCLVSGWGLLA-NGRMPTVLQCVNVSVVSEEVCSKLYDP-LYHPSMFCAGGGHD 198 C V+GWG ++ LQ + +V+ E C K Y M CAG Sbjct: 120 RNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREG 179 Query: 199 QKDSCNGDSGGPLICN----GYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQA 253 KD+C GD+GGPL C +L G+ S+G+ C Q PGVYTN+ ++ +WI + QA Sbjct: 180 GKDACKGDAGGPLSCKHNEVWHLVGITSWGEG-CAQRERPGVYTNVVEYVDWILEKTQA 237 >1P57-B nrPDB Length = 255 Score = 258 bits (661), Expect = 1e-69, Method: Composition-based stats. Identities = 76/245 (31%), Positives = 107/245 (43%), Gaps = 23/245 (9%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLE--- 87 I+ G D S PWQ +L + C G L+ WVL+AAHCF + Sbjct: 1 IVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAV 60 Query: 88 ADQEPGSQMVEASLSVRHPEY------NRPLLANDLMLIKLDESVSESDTIRSISIAS-- 139 A P + V H Y N +ND+ L+ L + ++ I+ + + + Sbjct: 61 AQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAG 120 Query: 140 QCPTAGNSCLVSGWGLLA-NGRMPTVLQCVNVSVVSEEVCS--KLYDPLYHPSMFCAGGG 196 Q G C V+GWG G+ VLQ V ++S +VC+ Y P MFCAG Sbjct: 121 QALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGYP 180 Query: 197 HDQKDSCNGDSGGPLICN--------GYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIE 248 D+C GDSGGP +C L G+VS+G C PGVYT + F EWI Sbjct: 181 EGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTG-CALAQKPGVYTKVSDFREWIF 239 Query: 249 KTVQA 253 + ++ Sbjct: 240 QAIKT 244 >3P8G-A nrPDB Length = 241 Score = 257 bits (657), Expect = 3e-69, Method: Composition-based stats. Identities = 75/240 (31%), Positives = 107/240 (44%), Gaps = 20/240 (8%) Query: 31 IINGEDCSPHSQPWQAALVMENE-LFCSGVLVHPQWVLSAAHCFQNS----------YTI 79 ++ G D PWQ +L + C L+ P W++SAAHC+ + +T Sbjct: 1 VVGGTDADEGEWPWQVSLHALGQGHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQWTA 60 Query: 80 GLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIA- 138 LGLH PG Q + HP +N D+ L++L++ S +R I + Sbjct: 61 FLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALLELEKPAEYSSMVRPICLPD 120 Query: 139 -SQCPTAGNSCLVSGWGLLA-NGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGG 196 S AG + V+GWG G +LQ + V+ + C L P M C G Sbjct: 121 ASHVFPAGKAIWVTGWGHTQYGGTGALILQKGEIRVIQQTTCENLLPQQITPRMMCVGFL 180 Query: 197 HDQKDSCNGDSGGPLI---CNG--YLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 251 DSC GDSGGPL +G + G+VS+G C Q PGVYT L F +WI++ Sbjct: 181 SGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWGDG-CAQRNKPGVYTRLPLFRDWIKENT 239 >2OCV-B nrPDB Length = 259 Score = 257 bits (656), Expect = 4e-69, Method: Composition-based stats. Identities = 79/255 (30%), Positives = 114/255 (44%), Gaps = 35/255 (13%) Query: 31 IINGEDCSPHSQPWQAALVMEN--ELFCSGVLVHPQWVLSAAHCF----------QNSYT 78 I+ G D PWQ L ++ EL C L+ +WVL+AAHC +N Sbjct: 1 IVEGWDAEKGIAPWQVMLFRKSPQELLCGASLISDRWVLTAAHCILYPPWDKNFTENDLL 60 Query: 79 IGLGLHSLEADQEPGSQMVEASLSVRHPEYN-RPLLANDLMLIKLDESVSESDTIRSISI 137 + +G HS + ++ HP YN R L D+ L+KL + V SD I + + Sbjct: 61 VRIGKHSRTRYERNVEKISMLEKIYVHPRYNWRENLDRDIALLKLKKPVPFSDYIHPVCL 120 Query: 138 A-----SQCPTAGNSCLVSGWGLLA-------NGRMPTVLQCVNVSVVSEEVCSKLYDPL 185 + AG V+GWG L N P+VLQ VN+ +V VC Sbjct: 121 PDKQTVTSLLRAGYKGRVTGWGNLRETWTTNINEIQPSVLQVVNLPIVERPVCKASTRIR 180 Query: 186 YHPSMFCAGG---GHDQKDSCNGDSGGPLICN------GYLQGLVSFGKAPCGQVGVPGV 236 +MFCAG + D+C GDSGGP + Y G+VS+G+ C + G G Sbjct: 181 ITDNMFCAGFKVNDTKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEG-CDRKGKYGF 239 Query: 237 YTNLCKFTEWIEKTV 251 YT++ + WI+K + Sbjct: 240 YTHVFRLKAWIQKVI 254 >1LTO-A nrPDB Length = 245 Score = 257 bits (656), Expect = 5e-69, Method: Composition-based stats. Identities = 73/241 (30%), Positives = 113/241 (46%), Gaps = 26/241 (10%) Query: 31 IINGEDCSPHSQPWQAALVMENE---LFCSGVLVHPQWVLSAAHCFQNSYT--IGLGLHS 85 I+ G++ PWQ +L + + FC G L+HPQWVL+AAHC L + Sbjct: 1 IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCLGPDVKDLATLRVQL 60 Query: 86 LEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIA--SQCPT 143 E Q++ S + HP++ D+ L++L+E V+ S + ++ + S+ Sbjct: 61 REQHLYYQDQLLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSRVHTVMLPPASETFP 120 Query: 144 AGNSCLVSGWGLLANGR---MPTVLQCVNVSVVSEEVCSKLYD---------PLYHPSMF 191 G C V+GWG + N P L+ V V ++ +C Y + M Sbjct: 121 PGMPCWVTGWGDVDNDEPLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIIRDDML 180 Query: 192 CAGGGHDQKDSCNGDSGGPLICN----GYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWI 247 CAG Q+DSC GDSGGPL+C G+VS+ + C Q PG+YT + + +WI Sbjct: 181 CAGNS--QRDSCKGDSGGPLVCKVNGTWLQAGVVSWDEG-CAQPNRPGIYTRVTYYLDWI 237 Query: 248 E 248 Sbjct: 238 H 238 >1FDP-A nrPDB Length = 235 Score = 256 bits (655), Expect = 6e-69, Method: Composition-based stats. Identities = 76/232 (32%), Positives = 124/232 (53%), Gaps = 12/232 (5%) Query: 30 QIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQN----SYTIGLGLHS 85 +I+ G + H++P+ A++ + C GVLV QWVLSAAHC ++ + LG HS Sbjct: 7 RILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQVLLGAHS 66 Query: 86 LEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIA--SQCPT 143 L EP ++ + +V HP+ + +DL+L++L E + +R + + Sbjct: 67 LSQP-EPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVA 125 Query: 144 AGNSCLVSGWGLLAN-GRMPTVLQCVNVSVVSEEVCSK--LYDPLYHPSMFCAGGGHDQK 200 G C V+GWG++ + GR P LQ V + V+ C++ +D + CA +++ Sbjct: 126 PGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITERLMCA--ESNRR 183 Query: 201 DSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 252 DSC GDSGGPL+C G L+G+V+ G CG PG+YT + + WI+ + Sbjct: 184 DSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVLA 235 >1KYN-A nrPDB Length = 235 Score = 256 bits (655), Expect = 7e-69, Method: Composition-based stats. Identities = 71/228 (31%), Positives = 122/228 (53%), Gaps = 9/228 (3%) Query: 31 IINGEDCSPHSQPWQAALVME---NELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLE 87 II G + PHS+P+ A L ++ + C G LV +VL+AAHC+ ++ + LG H+++ Sbjct: 1 IIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQ 60 Query: 88 ADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIA--SQCPTAG 145 E Q + A ++RHP+YN+ + ND+ML++L V + + +++ + G Sbjct: 61 RR-ENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPG 119 Query: 146 NSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNG 205 C V+GWG ++ R L+ V + V + C +++ C G ++K + G Sbjct: 120 TLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKAAFKG 179 Query: 206 DSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQA 253 DSGGPL+CN G+VS+GK+ P V+T + F WI T+++ Sbjct: 180 DSGGPLLCNNVAHGIVSYGKS---SGVPPEVFTRVSSFLPWIRTTMRS 224 >4H4F-A nrPDB Length = 249 Score = 256 bits (654), Expect = 7e-69, Method: Composition-based stats. Identities = 86/239 (35%), Positives = 117/239 (48%), Gaps = 18/239 (7%) Query: 31 IINGEDCSPHSQPWQAALVMEN----ELFCSGVLVHPQWVLSAAHCFQNS--YTIGLGLH 84 ++ GED PHS PWQ +L C G L+ +VL+AAHC N+ Y + +G + Sbjct: 1 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 60 Query: 85 SLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCP-- 142 +LE + E GS V H +N LL ND+ LIKL E V SDTI+ + + Sbjct: 61 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 120 Query: 143 TAGNSCLVSGWGLL-ANGRMPTVLQCVNVSVVSEEVCSK--LYDPLYHPSMFCAGGGHDQ 199 C V+GWG L NG + LQ VV CS+ + +M CAGG Sbjct: 121 PKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGG-DGV 179 Query: 200 KDSCNGDSGGPLICN-----GYLQGLVSFG-KAPCGQVGVPGVYTNLCKFTEWIEKTVQ 252 +CNGDSGGPL C + G+VSFG + C P VYT + + +WI + +Q Sbjct: 180 ISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 238 >1ETT-H nrPDB Length = 259 Score = 256 bits (654), Expect = 9e-69, Method: Composition-based stats. Identities = 74/255 (29%), Positives = 113/255 (44%), Gaps = 35/255 (13%) Query: 31 IINGEDCSPHSQPWQAALVMEN--ELFCSGVLVHPQWVLSAAHCF----------QNSYT 78 I+ G+D PWQ L ++ EL C L+ +WVL+AAHC + Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDLL 60 Query: 79 IGLGLHSLEADQEPGSQMVEASLSVRHPEYN-RPLLANDLMLIKLDESVSESDTIRSISI 137 + +G HS + ++ HP YN + L D+ L+KL + SD I + + Sbjct: 61 VRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVCL 120 Query: 138 A-----SQCPTAGNSCLVSGWGLLANG-------RMPTVLQCVNVSVVSEEVCSKLYDPL 185 ++ AG V+GWG P+VLQ VN+ +V VC Sbjct: 121 PDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVERPVCKASTRIR 180 Query: 186 YHPSMFCAGGGHD---QKDSCNGDSGGPLICN------GYLQGLVSFGKAPCGQVGVPGV 236 +MFCAG + D+C GDSGGP + Y G+VS+G+ C + G G Sbjct: 181 ITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWGEG-CDRDGKYGF 239 Query: 237 YTNLCKFTEWIEKTV 251 YT++ + +WI+K + Sbjct: 240 YTHVFRLKKWIQKVI 254 >1PYT-D nrPDB Length = 251 Score = 255 bits (653), Expect = 1e-68, Method: Composition-based stats. Identities = 86/246 (34%), Positives = 121/246 (49%), Gaps = 17/246 (6%) Query: 23 LVSGSCSQIINGEDCSPHSQPWQAALVMEN----ELFCSGVLVHPQWVLSAAHCFQNS-- 76 ++++ GED PHS PWQ +L C G L+ P VL+AAHC N+ Sbjct: 6 FQPNLSARVVGGEDAIPHSWPWQISLQYLRDNTWRHTCGGTLITPNHVLTAAHCISNTLT 65 Query: 77 YTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSIS 136 Y + LG ++LE + E GS V H ++N L+ ND+ LIKL E+V DTI+ Sbjct: 66 YRVALGKNNLEVEDEAGSLYVGVDTIFVHEKWNSFLVRNDIALIKLAETVELGDTIQVAC 125 Query: 137 IASQCP--TAGNSCLVSGWGLL-ANGRMPTVLQCVNVSVVSEEVCSK--LYDPLYHPSMF 191 + S+ C V+GWG L NG + LQ VV CS+ + +M Sbjct: 126 LPSEGSLLPQDYPCFVTGWGRLYTNGPIAAELQQGLQPVVDYATCSQRDWWGTTVKETMV 185 Query: 192 CAGGGHDQKDSCNGDSGGPLIC----NGYLQGLVSFGKA-PCGQVGVPGVYTNLCKFTEW 246 CAGG +CNGDSGGPL C ++G+VSFG C P V+T + + +W Sbjct: 186 CAGG-DGVISACNGDSGGPLNCQADGQWDVRGIVSFGSGLSCNTFKKPTVFTRVSAYIDW 244 Query: 247 IEKTVQ 252 I + +Q Sbjct: 245 INQKLQ 250 >1BRU-P nrPDB Length = 241 Score = 255 bits (652), Expect = 1e-68, Method: Composition-based stats. Identities = 90/243 (37%), Positives = 122/243 (50%), Gaps = 21/243 (8%) Query: 31 IINGEDCSPHSQPWQAALVMEN----ELFCSGVLVHPQWVLSAAHCFQNS--YTIGLGLH 84 ++ GED P+S PWQ +L ++ C G LV WVL+AAHC +S Y + LG H Sbjct: 1 VVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISSSRTYRVVLGRH 60 Query: 85 SLEADQEPGSQMVEASLSVRHPEYNRPLL--ANDLMLIKLDESVSESDTIRSISIASQCP 142 SL EPGS V+ S V H ++N L ND+ L+KL VS +D I+ + + Sbjct: 61 SLST-NEPGSLAVKVSKLVVHQDWNSNQLSNGNDIALLKLASPVSLTDKIQLGCLPAAGT 119 Query: 143 --TAGNSCLVSGWGLL-ANGRMPTVLQCVNVSVVSEEVCSK--LYDPLYHPSMFCAGGGH 197 C V+GWG L NG P +LQ + VV CSK + +M CAGG Sbjct: 120 ILPNNYVCYVTGWGRLQTNGASPDILQQGQLLVVDYATCSKPGWWGSTVKTNMICAGG-D 178 Query: 198 DQKDSCNGDSGGPLICNG-----YLQGLVSFGKA-PCGQVGVPGVYTNLCKFTEWIEKTV 251 SCNGDSGGPL C G + G+VSFG + C P V+T + + +WI + Sbjct: 179 GIISSCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRVSNYIDWINSVI 238 Query: 252 QAS 254 + Sbjct: 239 ANN 241 >1VR1-H nrPDB Length = 261 Score = 255 bits (652), Expect = 1e-68, Method: Composition-based stats. Identities = 75/259 (28%), Positives = 112/259 (43%), Gaps = 39/259 (15%) Query: 31 IINGEDCSPHSQPWQAALVMENE------LFCSGVLVHPQWVLSAAHCF----------Q 74 I+ G D PWQ L ++ C L+ +WVL+AAHC + Sbjct: 1 IVEGSDAEIGMSPWQVMLFAKHRRSPGERFLCGASLISDRWVLTAAHCLLYPPWDKNFTE 60 Query: 75 NSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYN-RPLLANDLMLIKLDESVSESDTIR 133 N + +G HS + ++ HP YN R L D+ L+KL + V+ SD I Sbjct: 61 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIH 120 Query: 134 SISIASQCP-----TAGNSCLVSGWGLLANG-------RMPTVLQCVNVSVVSEEVCSKL 181 + + + AG V+GWG L P+VLQ VN+ +V VC Sbjct: 121 PVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDS 180 Query: 182 YDPLYHPSMFCAGG---GHDQKDSCNGDSGGPLICN------GYLQGLVSFGKAPCGQVG 232 +MFCA + D+C GDSGGP + Y G+VS+G+ C + G Sbjct: 181 TRIRITDNMFCAYYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEG-CDRDG 239 Query: 233 VPGVYTNLCKFTEWIEKTV 251 G YT++ + +WI+K + Sbjct: 240 KYGFYTHVFRLKKWIQKVI 258 >5FCR-A nrPDB Length = 234 Score = 254 bits (650), Expect = 2e-68, Method: Composition-based stats. Identities = 77/234 (32%), Positives = 123/234 (52%), Gaps = 13/234 (5%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQ-----NSYTIGLGLHS 85 I+ G++ + H++P+ A++ + C G L+ QWVLSAAHC +S + LG HS Sbjct: 1 ILGGQEAAAHARPYMASVQVNGTHVCGGTLLDEQWVLSAAHCMDGVTDDDSVQVLLGAHS 60 Query: 86 LEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISI--ASQCPT 143 L A EP + + V HP L +DL+L KL ++ S +R + + + Sbjct: 61 LSAP-EPYKRWYDVQSVVPHPGSRPDSLEDDLILFKLSQNASLGPHVRPLPLQYEDKEVE 119 Query: 144 AGNSCLVSGWGL-LANGRMPTVLQCVNVSVVSEEVCS--KLYDPLYHPSMFCAGGGHDQK 200 G C V+GWG+ GR P VL + VS+++ C+ +D + +M CA +++ Sbjct: 120 PGTLCDVAGWGVVTHAGRRPDVLHQLRVSIMNRTTCNLRTYHDGVVTINMMCA--ESNRR 177 Query: 201 DSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 D+C GDSG PL+C ++G+V++G CG PGVYT + + WIE + Sbjct: 178 DTCRGDSGSPLVCGDAVEGVVTWGSRVCGNGKKPGVYTRVSSYRMWIENITNGN 231 >1FIZ-A nrPDB Length = 263 Score = 252 bits (645), Expect = 1e-67, Method: Composition-based stats. Identities = 69/252 (27%), Positives = 110/252 (43%), Gaps = 29/252 (11%) Query: 31 IINGEDCSPHSQPWQAALV------MENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLH 84 ++ G P + PW +L C G+L++ WVL+AAHCF+N + Sbjct: 1 VVGGMSAEPGAWPWMVSLQIFMYHNNRRYHTCGGILLNSHWVLTAAHCFKNKKKVTDWRL 60 Query: 85 SLEADQ---------EPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSI 135 A++ +P Q + H +Y L ND+ LIK+ V I Sbjct: 61 IFGANEVVWGSNKPVKPPLQERFVEEIIIHEKYVSGLEINDIALIKITPPVPCGPFIGPG 120 Query: 136 SIA---SQCPTAGNSCLVSGWGLLAN--GRMPTVLQCVNVSVVSEEVCS--KLYDPLYHP 188 + + P A +C V+GWG L R LQ V+++ E+C+ + Y+ Sbjct: 121 CLPQFKAGPPRAPQTCWVTGWGYLKEKGPRTSPTLQEARVALIDLELCNSTRWYNGRIRS 180 Query: 189 SMFCAGGGHDQKDSCNGDSGGPLICNG------YLQGLVSFGKAPCGQVGVPGVYTNLCK 242 + CAG + D+C GDSGGPL+C + G+ S+G C + PGVYT+ Sbjct: 181 TNVCAGYPRGKIDTCQGDSGGPLMCRDRAENTFVVVGITSWGVG-CARAKRPGVYTSTWP 239 Query: 243 FTEWIEKTVQAS 254 + WI + ++ Sbjct: 240 YLNWIASKIGSN 251 >4Z6A-H nrPDB Length = 249 Score = 251 bits (641), Expect = 2e-67, Method: Composition-based stats. Identities = 74/238 (31%), Positives = 110/238 (46%), Gaps = 17/238 (7%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQN-----SYTIGLGLHS 85 I+ G+ C PWQ L++ C G L++ WV+SAAHCF + LG H Sbjct: 1 IVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLGEHD 60 Query: 86 LEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAG 145 L Q + + Y +D+ L++L + V +D + + + + + Sbjct: 61 LSEHD-GDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSER 119 Query: 146 NSC-----LVSGWG-LLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQ 199 LVSGWG LL G L +NV + + C Y MFCAG Sbjct: 120 TLAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQDCEASYPGKITEYMFCAGYSDGS 179 Query: 200 KDSCNGDSGGPLICN----GYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQA 253 KDSC GDSGGP + YL G+VS+G+ C VG GVYT + ++ EW++K +++ Sbjct: 180 KDSCKGDSGGPHATHYRGTWYLTGIVSWGQG-CATVGHFGVYTRVSQYIEWLQKLMRS 236 >1FIW-A nrPDB Length = 290 Score = 250 bits (639), Expect = 4e-67, Method: Composition-based stats. Identities = 66/252 (26%), Positives = 108/252 (42%), Gaps = 29/252 (11%) Query: 31 IINGEDCSPHSQPWQAALV------MENELFCSGVLVHPQWVLSAAHCFQNSYTIGLG-- 82 II G+D + + PW +L C G L++ QW+L+AAHCF+ + Sbjct: 1 IIGGQDAAHGAWPWMVSLQIFTYHNNRRYHVCGGSLLNSQWLLTAAHCFRIKKKVTDWRL 60 Query: 83 -------LHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSI 135 +P Q + H +Y+ AND+ L+K+ V+ I Sbjct: 61 IFGAKEVEWGTNKPVKPPLQERYVEKIIIHEKYSASSEANDIALMKITPPVTCGHFIGPG 120 Query: 136 SIA---SQCPTAGNSCLVSGWGLLANG--RMPTVLQCVNVSVVSEEVCS--KLYDPLYHP 188 + + P +C V+GWG L R +LQ V ++ +C+ + Y+ Sbjct: 121 CLPQFRAGPPRVPQTCWVAGWGFLQENARRTSPMLQEARVDLIDLGLCNSTRWYNGRIRS 180 Query: 189 SMFCAGGGHDQKDSCNGDSGGPLICNG------YLQGLVSFGKAPCGQVGVPGVYTNLCK 242 + CAG + D+C GDSGGPL+C + G+ S+G C + PGVYT+ Sbjct: 181 TNVCAGYPEGKIDTCQGDSGGPLMCKDSAENSYVVVGITSWGVG-CARAKRPGVYTSTWS 239 Query: 243 FTEWIEKTVQAS 254 + WI + ++ Sbjct: 240 YLNWIASKIGST 251 >1MZD-A nrPDB Length = 240 Score = 250 bits (639), Expect = 5e-67, Method: Composition-based stats. Identities = 88/235 (37%), Positives = 123/235 (52%), Gaps = 15/235 (6%) Query: 30 QIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHC-----FQNSYTIGLGLH 84 +II G++ SPHS+P+ A++ C GVL+ PQWVL+AAHC S T+ LG H Sbjct: 2 EIIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAH 61 Query: 85 SLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCP-T 143 SL E Q +E + +ND+ML+KL + + ++ + I S+ Sbjct: 62 SLSK-NEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHIRSKTSLR 120 Query: 144 AGNSCLVSGWGLLANG--RMPTVLQCVNVSVVSEEVC-SKLY---DPLYHPSMFCAGGGH 197 +G C V+GWG R L+ V V+V+S ++C S+ Y DP M CAG Sbjct: 121 SGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAGDAK 180 Query: 198 DQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLC-KFTEWIEKTV 251 QKDSC GD+GGPLIC G +VS G CG PG+YT L K+ WI+ + Sbjct: 181 GQKDSCKGDAGGPLICKGVFHAIVSGGHE-CGVATKPGIYTLLTKKYQTWIKSNL 234 >1ORF-A nrPDB Length = 234 Score = 250 bits (638), Expect = 6e-67, Method: Composition-based stats. Identities = 75/233 (32%), Positives = 117/233 (50%), Gaps = 11/233 (4%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHC-FQNSYTIGLGLHSLEAD 89 II G + +PHS+P+ L ++ + C+G L+ WVL+AAHC + LG HS+ Sbjct: 1 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSI-TR 59 Query: 90 QEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIA--SQCPTAGNS 147 +EP Q++ +P Y+ DL L++L E + + + + G Sbjct: 60 EEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLTEKAKINKYVTILHLPKKGDDVKPGTM 119 Query: 148 CLVSGWGLLANG-RMPTVLQCVNVSVVSEEVCSKL----YDPLYHPSMFCAGGGHDQKDS 202 C V+GWG N L+ V ++++ +VC+ ++P+ +M CAG +DS Sbjct: 120 CQVAGWGRTHNSASWSDTLREVEITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDS 179 Query: 203 CNGDSGGPLICNGYLQGLVSFG-KAPCGQVGVPGVYTNLC-KFTEWIEKTVQA 253 CNGDSG PL+C G +G+ SFG + CG PGVY L K WI T++ Sbjct: 180 CNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIKG 232 >3F6U-H nrPDB Length = 240 Score = 248 bits (634), Expect = 2e-66, Method: Composition-based stats. Identities = 73/239 (30%), Positives = 117/239 (48%), Gaps = 19/239 (7%) Query: 32 INGEDCSPHSQPWQAALV-MENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLE-AD 89 I+G+ PWQ L+ + +L C VL+HP WVL+AAHC S + + L + Sbjct: 2 IDGKMTRRGDSPWQVVLLDSKKKLACGAVLIHPSWVLTAAHCMDESKKLLVRLGEYDLRR 61 Query: 90 QEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCP------T 143 E ++ HP Y++ ND+ L+ L + + S TI I + Sbjct: 62 WEKWELDLDIKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPICLPDSGLAERELNQ 121 Query: 144 AGNSCLVSGWGLLANG------RMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGH 197 AG LV+GWG ++ VL + + VV CS++ + +M CAG Sbjct: 122 AGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSNMVSENMLCAGILG 181 Query: 198 DQKDSCNGDSGGPLICN----GYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 252 D++D+C GDSGGP++ + +L GLVS+G+ CG + GVYT + ++ +WI ++ Sbjct: 182 DRQDACEGDSGGPMVASFHGTWFLVGLVSWGEG-CGLLHNYGVYTKVSRYLDWIHGHIR 239 >4Q7Y-A nrPDB Length = 250 Score = 247 bits (631), Expect = 4e-66, Method: Composition-based stats. Identities = 77/233 (33%), Positives = 117/233 (50%), Gaps = 10/233 (4%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQ----NSYTIGLGLHSL 86 II G + +PHS+P+ A++ + C G L+ +WV+SAAHCF + + LG H L Sbjct: 1 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 60 Query: 87 EADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIA---SQCPT 143 EP Q+ HP+Y+ AND+ L++L+ S + + + ++ PT Sbjct: 61 ST-AEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRLPGRRARPPT 119 Query: 144 AGNSCLVSGWGLLAN-GRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHD-QKD 201 AG C V+GWG +++ +P L V V+ +VC+ + +M C G ++ Sbjct: 120 AGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRG 179 Query: 202 SCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 C+ DSGGPL+C GLVSF CG P VYT + F WI V+ S Sbjct: 180 FCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRRS 232 >2RDL-A nrPDB Length = 226 Score = 245 bits (626), Expect = 1e-65, Method: Composition-based stats. Identities = 71/231 (30%), Positives = 111/231 (48%), Gaps = 12/231 (5%) Query: 31 IINGEDCSPHSQPWQAALVM----ENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSL 86 II G +C PH++P+ A L + + CSG L+ +V++AAHC S T+ LG H+ Sbjct: 1 IIGGTECRPHARPYMAYLEIVTPENHLSACSGFLIRRNFVMTAAHCAGRSITVLLGAHNK 60 Query: 87 EADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIR--SISIASQCPTA 144 + E Q +E HP+Y+ L+ ND+ML+KL E + + + IS S Sbjct: 61 KVK-EDTWQKLEVEKQFPHPKYDDRLVLNDIMLLKLKEKANLTLGVGTLPISAKSNSIPP 119 Query: 145 GNSCLVSGWGLLANGRMP-TVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSC 203 G C GWG P LQ V + ++ + C K ++ + C G ++ Sbjct: 120 GRVCRAVGWGRTNVNEPPSDTLQEVKMRILDPQAC-KHFEDFHQEPQLCVGNPKKIRNVY 178 Query: 204 NGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 GDSGGPL+C G QG+ S+ P V+T + + WI K ++ + Sbjct: 179 KGDSGGPLLCAGIAQGIASYVL---RNAKPPSVFTRISHYRPWINKILREN 226 >5TO3-B nrPDB Length = 409 Score = 245 bits (626), Expect = 1e-65, Method: Composition-based stats. Identities = 78/255 (30%), Positives = 113/255 (44%), Gaps = 35/255 (13%) Query: 31 IINGEDCSPHSQPWQAALVMEN--ELFCSGVLVHPQWVLSAAHCF----------QNSYT 78 I+ G D PWQ L ++ EL C L+ +WVL+AAHC +N Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 79 IGLGLHSLEADQEPGSQMVEASLSVRHPEYN-RPLLANDLMLIKLDESVSESDTIRSISI 137 + +G HS + ++ HP YN R L D+ L+KL + V+ SD I + + Sbjct: 61 VRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCL 120 Query: 138 ASQCP-----TAGNSCLVSGWGLLANG-------RMPTVLQCVNVSVVSEEVCSKLYDPL 185 + AG V+GWG L P+VLQ VN+ +V VC Sbjct: 121 PDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIR 180 Query: 186 YHPSMFCAGG---GHDQKDSCNGDSGGPLICN------GYLQGLVSFGKAPCGQVGVPGV 236 +MFCAG + D+C GDSGGP + Y G+VS G C + G G Sbjct: 181 ITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSAGAG-CDRDGKYGF 239 Query: 237 YTNLCKFTEWIEKTV 251 YT++ + +WI+K + Sbjct: 240 YTHVFRLKKWIQKVI 254 >1AZZ-A nrPDB Length = 226 Score = 245 bits (626), Expect = 2e-65, Method: Composition-based stats. Identities = 70/222 (31%), Positives = 117/222 (52%), Gaps = 7/222 (3%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNS--YTIGLGLHSLEA 88 I+ G + P+S P QAAL +++ FC G L+ P+W+L+AAHC + + LG H++ Sbjct: 1 IVGGVEAVPNSWPHQAALFIDDMYFCGGSLISPEWILTAAHCMDGAGFVDVVLGAHNIR- 59 Query: 89 DQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSC 148 + E ++++ H YN +++ND+ +I+L V+ + I ++ + S G Sbjct: 60 EDEATQVTIQSTDFTVHENYNSFVISNDIAVIRLPVPVTLTAAIATVGLPSTDVGVGTVV 119 Query: 149 LVSGWGLLANGRM--PTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGD 206 +GWGL ++ + VL+ V+V ++S C +Y + C K +CNGD Sbjct: 120 TPTGWGLPSDSALGISDVLRQVDVPIMSNADCDAVY-GIVTDGNICI-DSTGGKGTCNGD 177 Query: 207 SGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIE 248 SGGPL NG G+ SFG A + G P +T + F +WI+ Sbjct: 178 SGGPLNYNGLTYGITSFGAAAGCEAGYPDAFTRVTYFLDWIQ 219 >1FUJ-A nrPDB Length = 221 Score = 244 bits (624), Expect = 2e-65, Method: Composition-based stats. Identities = 73/232 (31%), Positives = 112/232 (48%), Gaps = 21/232 (9%) Query: 31 IINGEDCSPHSQPWQAALVMENE---LFCSGVLVHPQWVLSAAHCFQN----SYTIGLGL 83 I+ G + PHS+P+ A+L M FC G L+HP +VL+AAHC ++ + LG Sbjct: 1 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 60 Query: 84 HSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPT 143 H++ QEP Q + + Y+ ND++LI+L + S ++ ++ + Q Sbjct: 61 HNVRT-QEPTQQHFSVAQVFLN-NYDAENKLNDILLIQLSSPANLSASVATVQLPQQDQP 118 Query: 144 A--GNSCLVSGWGLLANGRMPT-VLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQK 200 G CL GWG + P VLQ +NV+VV+ P C + Sbjct: 119 VPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVT---------FFCRPHNICTFVPRRKA 169 Query: 201 DSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 252 C GDSGGPLIC+G +QG+ SF C P +T + + +WI T++ Sbjct: 170 GICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 221 >1BDA-A nrPDB Length = 265 Score = 244 bits (624), Expect = 3e-65, Method: Composition-based stats. Identities = 71/254 (27%), Positives = 109/254 (42%), Gaps = 33/254 (12%) Query: 30 QIINGEDCSPHSQPWQAALVMENE------LFCSGVLVHPQWVLSAAHCFQNSY-----T 78 +I G S PWQAA+ ++ C G+L+ W+LSAAHCFQ + T Sbjct: 13 RIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQERFPPHHLT 72 Query: 79 IGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLD----ESVSESDTIRS 134 + LG E Q E + H E++ ND+ L++L ES +R+ Sbjct: 73 VILGRTYRVVPGEE-EQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRT 131 Query: 135 ISIASQCPTAG--NSCLVSGWGLLANGR--MPTVLQCVNVSVVSEEVCSKLY--DPLYHP 188 + + C +SG+G L+ +V + C+ + + Sbjct: 132 VCLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCTSQHLLNRTVTD 191 Query: 189 SMFCAGGGHDQK------DSCNGDSGGPLIC----NGYLQGLVSFGKAPCGQVGVPGVYT 238 +M CAG D+C GDSGGPL+C L G++S+G CGQ VPGVYT Sbjct: 192 NMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWGLG-CGQKDVPGVYT 250 Query: 239 NLCKFTEWIEKTVQ 252 + + +WI ++ Sbjct: 251 KVTNYLDWIRDNMR 264 >1SC8-U nrPDB Length = 262 Score = 243 bits (621), Expect = 5e-65, Method: Composition-based stats. Identities = 80/250 (32%), Positives = 113/250 (45%), Gaps = 28/250 (11%) Query: 30 QIINGEDCSPHSQPWQAALVMENE-----LFCSGVLVHPQWVLSAAHCF-----QNSYTI 79 +II GE + +QPW AA+ + C G L+ P WV+SA HCF + Y + Sbjct: 15 KIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIV 74 Query: 80 GLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLA--NDLMLIKLDES----VSESDTIR 133 LG L G E + H +Y+ LA ND+ L+K+ S TI+ Sbjct: 75 YLGRSRLN-SNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQ 133 Query: 134 SISIAS--QCPTAGNSCLVSGWGLLANGRM--PTVLQCVNVSVVSEEVCSK--LYDPLYH 187 +IS+ S P G SC ++G+G + P L+ V ++S C + Y Sbjct: 134 TISLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVT 193 Query: 188 PSMFCAGGGHDQKDSCNGDSGGPLIC----NGYLQGLVSFGKAPCGQVGVPGVYTNLCKF 243 M CA + DSC GDSGGPL+C L G+VS+G+ C PGVYT + F Sbjct: 194 TKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRG-CALKDKPGVYTRVSHF 252 Query: 244 TEWIEKTVQA 253 WI + Sbjct: 253 LPWIRSHTKE 262 >5LHN-A nrPDB Length = 247 Score = 242 bits (619), Expect = 9e-65, Method: Composition-based stats. Identities = 83/248 (33%), Positives = 121/248 (48%), Gaps = 29/248 (11%) Query: 31 IINGEDCSPHSQPWQAALVMENE------LFCSGVLVHPQWVLSAAHCF-----QNSYTI 79 I+ GE +QPW AA+ +N+ C G L+ P WV SAAHCF + +Y + Sbjct: 1 IVGGEFTEVENQPWFAAIYQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVV 60 Query: 80 GLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLA--NDLMLIKLDES----VSESDTIR 133 LG S E+ PG E + H Y LA ND+ L+K+ S S +I+ Sbjct: 61 YLG-QSKESSYNPGEMKFEVEQLILHEYYREDSLAYHNDIALLKIRTSTGQCAQPSRSIQ 119 Query: 134 SISIASQ--CPTAGNSCLVSGWGLLANGRM--PTVLQCVNVSVVSEEVCSK--LYDPLYH 187 +I++ + G+ C ++G+G + P L+ V +VS E C + Y + Sbjct: 120 TIALPPRFTDAPFGSDCEITGFGKESESDYLYPKNLKMSVVKLVSHEQCMQPHYYGSEIN 179 Query: 188 PSMFCAGGGHDQKDSCNGDSGGPLICN----GYLQGLVSFGKAPCGQVGVPGVYTNLCKF 243 M CA + DSC GDSGGPLICN L G+VS+G+ C + PGVYT + F Sbjct: 180 YKMLCAADPEWKTDSCKGDSGGPLICNIEGRPTLSGIVSWGRG-CAEKNKPGVYTRVSHF 238 Query: 244 TEWIEKTV 251 +WI+ + Sbjct: 239 LDWIQSHI 246 >4XDE-A nrPDB Length = 257 Score = 242 bits (617), Expect = 2e-64, Method: Composition-based stats. Identities = 75/244 (30%), Positives = 109/244 (44%), Gaps = 26/244 (10%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQN-----SYTIGLGLHS 85 ++ G + P+ AAL + FC+G L+ P WVL+AAHC Q+ T+ LG Sbjct: 3 VVGGLVALRGAHPYIAALYWGHS-FCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVLGQER 61 Query: 86 LEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVS-----ESDTIRSISIASQ 140 EP Q + H ++ +DL L++L E S ++ +S+ S Sbjct: 62 RNHSCEPC-QTLAVRSYRLHEAFSPVSYQHDLALLRLQEDADGSCALLSPYVQPVSLPSG 120 Query: 141 CPTA--GNSCLVSGWGLLANG--RMPTVLQCVNVSVVSEEVCSK--LYDPLYHPSMFCAG 194 C V+GWG G + LQ V +S E CS ++ P M CAG Sbjct: 121 AARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGSSILPGMLCAG 180 Query: 195 GGHDQKDSCNGDSGGPLICNG-------YLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWI 247 D+C GDSGGPL+C LQG++S+G CG PGVYT++ + WI Sbjct: 181 FLEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWGSG-CGDRNKPGVYTDVAYYLAWI 239 Query: 248 EKTV 251 + Sbjct: 240 REHT 243 >4IGD-A nrPDB Length = 406 Score = 241 bits (615), Expect = 3e-64, Method: Composition-based stats. Identities = 72/257 (28%), Positives = 106/257 (41%), Gaps = 30/257 (11%) Query: 23 LVSGSCSQIINGEDCSPHSQPWQAALVM-ENELFCSGVLVHPQWVLSAAHCFQ------- 74 +QI NG + PW A L + FC G L+ W+++AAHC Sbjct: 148 FSRKLMAQIFNGRPAQKGTTPWIAMLSHLNGQPFCGGSLLGSSWIVTAAHCLHQSLDPED 207 Query: 75 -----------NSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLD 123 + + I LG H + Q + + HP+Y+ ND+ L++L Sbjct: 208 PTLRDSDLLSPSDFKIILGKH-WRLRSDENEQHLGVKHTTLHPQYDPNTFENDVALVELL 266 Query: 124 ESVSESDTIRSISIASQCPTAGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYD 183 ES + + I + G +VSGWG R P L + + +V C K Y Sbjct: 267 ESPVLNAFVMPICLPEGPQQEGAMVIVSGWGKQFLQRFPETLMEIEIPIVDHSTCQKAYA 326 Query: 184 P---LYHPSMFCAGGGHDQKDSCNGDSGGPLIC------NGYLQGLVSFGKAPCGQVGVP 234 P M CAG KD+C GDSGGP++ YL G VS+G CG+ Sbjct: 327 PLKKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGD-DCGKKDRY 385 Query: 235 GVYTNLCKFTEWIEKTV 251 GVY+ + +WI++ Sbjct: 386 GVYSYIHHNKDWIQRVT 402 >3RP2-A nrPDB Length = 224 Score = 240 bits (614), Expect = 3e-64, Method: Composition-based stats. Identities = 64/228 (28%), Positives = 103/228 (45%), Gaps = 12/228 (5%) Query: 31 IINGEDCSPHSQPWQAALVMEN----ELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSL 86 II G + PHS+P+ A L + + C G L+ Q+VL+AAHC T+ LG H + Sbjct: 1 IIGGVESIPHSRPYMAHLDIVTEKGLRVICGGFLISRQFVLTAAHCKGREITVILGAHDV 60 Query: 87 EADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCP--TA 144 E Q ++ + H YN +D+ML+KL++ V + + + + S Sbjct: 61 RKR-ESTQQKIKVEKQIIHESYNSVPNLHDIMLLKLEKKVELTPAVNVVPLPSPSDFIHP 119 Query: 145 GNSCLVSGWGLLA-NGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSC 203 G C +GWG L+ V + ++ E+ C Y + C G + + Sbjct: 120 GAMCWAAGWGKTGVRDPTSYTLREVELRIMDEKACVD-YRYYEYKFQVCVGSPTTLRAAF 178 Query: 204 NGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 251 GDSGGPL+C G G+VS+G P ++T + + WI + Sbjct: 179 MGDSGGPLLCAGVAHGIVSYGHP---DAKPPAIFTRVSTYVPWINAVI 223 >2XRC-A nrPDB Length = 565 Score = 240 bits (613), Expect = 4e-64, Method: Composition-based stats. Identities = 71/234 (30%), Positives = 112/234 (47%), Gaps = 19/234 (8%) Query: 30 QIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEAD 89 +I+ G+ PWQ A+ + + C G+ + W+L+AAHC + S T + + D Sbjct: 321 RIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVD 380 Query: 90 Q-EPGSQMV---EASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPT-- 143 P + + + H YN ND+ LI++ + ++ D SI + P Sbjct: 381 WIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSP 440 Query: 144 ----AGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHP-SMFCAGGGHD 198 ++C+VSGWG + LQ V ++S CSK Y ++ M CAG Sbjct: 441 YLFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISN--CSKFYGNRFYEKEMECAGTYDG 498 Query: 199 QKDSCNGDSGGPLICNG-----YLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWI 247 D+C GDSGGPL+C Y+ G+VS+G+ CG+ PGVYT + + +WI Sbjct: 499 SIDACKGDSGGPLVCMDANNVTYVWGVVSWGEN-CGKPEFPGVYTKVANYFDWI 551 >1YC0-A nrPDB Length = 283 Score = 240 bits (613), Expect = 5e-64, Method: Composition-based stats. Identities = 78/243 (32%), Positives = 122/243 (50%), Gaps = 23/243 (9%) Query: 30 QIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCF-----QNSYTIGLGLH 84 +II G P S PW AA+ + + FC+G LVH WV+SAAHCF ++S ++ LG H Sbjct: 35 RIIGGSSSLPGSHPWLAAIYIGDS-FCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQH 93 Query: 85 SLEADQEPGSQMVEASLSVRHPEYNRPL-LANDLMLIKLDES----VSESDTIRSISIAS 139 +Q + + Y+ +DL+LI+L + + S ++ I + Sbjct: 94 FFNR-TTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLPE 152 Query: 140 --QCPTAGNSCLVSGWGLLANG--RMPTVLQCVNVSVVSEEVCSK--LYDPLYHPSMFCA 193 AG+ C ++GWG L + L+ V +V++ CS +Y P+M CA Sbjct: 153 PGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNMLCA 212 Query: 194 GGGHDQKDSCNGDSGGPLICNG----YLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEK 249 G + D+C GDSGGPL C YL G++S+G CG++ PGVYT + + +WI Sbjct: 213 GYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDG-CGRLHKPGVYTRVANYVDWIND 271 Query: 250 TVQ 252 ++ Sbjct: 272 RIR 274 >1Q3X-A nrPDB Length = 328 Score = 238 bits (608), Expect = 2e-63, Method: Composition-based stats. Identities = 66/246 (26%), Positives = 107/246 (43%), Gaps = 24/246 (9%) Query: 27 SCSQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCF----QNSYTIGLG 82 + +I G+ P PWQ ++ +G L++ WVL+AAH ++ + + Sbjct: 83 TGGRIYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNWVLTAAHAVYEQKHDASALDIR 140 Query: 83 LHSLEADQEPGSQMVEASLSVRHPEY-NRPLLANDLMLIKLDESVSESDTIRSISIASQC 141 + +L+ +Q H Y + ND+ LIKL+ V + I I + + Sbjct: 141 MGTLKRLSPHYTQAWS-EAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPICLPRKE 199 Query: 142 PT----AGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYD------PLYHPSMF 191 + SGWGL G + L V++ +V + C+ Y+ +M Sbjct: 200 AESFMRTDDIGTASGWGLTQRGFLARNLMYVDIPIVDHQKCTAAYEKPPYPRGSVTANML 259 Query: 192 CAGGGHDQKDSCNGDSGGPLIC------NGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTE 245 CAG KDSC GDSGG L+ ++ G+VS+G CG+ G GVYT + + Sbjct: 260 CAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVYTKVINYIP 319 Query: 246 WIEKTV 251 WIE + Sbjct: 320 WIENII 325 >4IW4-E nrPDB Length = 279 Score = 238 bits (607), Expect = 2e-63, Method: Composition-based stats. Identities = 76/268 (28%), Positives = 117/268 (43%), Gaps = 49/268 (18%) Query: 31 IINGEDCSPHSQPWQAALVMEN-------ELFCSGVLVHPQWVLSAAHCFQNSY------ 77 II G + P PWQA +V+E+ + F SG L+ W+L+AAH ++ Sbjct: 1 IIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVI 60 Query: 78 -------TIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESD 130 T+ LGLH + + G+ A+ V HP++N +D+ L++L E V Sbjct: 61 PVSKEHVTVYLGLH--DVRDKSGAVNSSAARVVLHPDFNIQNYNHDIALVQLQEPVPLGP 118 Query: 131 TIRSISIA---SQCPTAGNSCLVSGWGLLANG------------RMPTVLQCVNVSVVSE 175 + + + + P LV+GWG+ + VLQ V + VV Sbjct: 119 HVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPH 178 Query: 176 EVCSKLYDPL-----YHPSMFCAGGGHDQKDSCNGDSGGPLI------CNGYLQGLVSF- 223 C Y+ +MFCAG KD+C GDSGG + +QGLVS+ Sbjct: 179 AECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGGAFVIFDDLSQRWVVQGLVSWG 238 Query: 224 GKAPCGQVGVPGVYTNLCKFTEWIEKTV 251 G CG V GVYT + + +W+ + + Sbjct: 239 GPEECGSKQVYGVYTKVSNYVDWVWEQM 266 >4DJZ-B nrPDB Length = 251 Score = 237 bits (606), Expect = 3e-63, Method: Composition-based stats. Identities = 71/249 (28%), Positives = 104/249 (41%), Gaps = 30/249 (12%) Query: 31 IINGEDCSPHSQPWQAALVM-ENELFCSGVLVHPQWVLSAAHCFQ--------------- 74 I NG + PW A L + FC G L+ W+++AAHC Sbjct: 1 IFNGRPAQKGTTPWIAMLSHLNGQPFCGGSLLGSSWIVTAAHCLHQSLDPKDPTLRDSDL 60 Query: 75 ---NSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDT 131 + + I LG H + Q + + HP+Y+ ND+ L++L ES + Sbjct: 61 LSPSDFKIILGKH-WRLRSDENEQHLGVKHTTLHPQYDPNTFENDVALVELLESPVLNAF 119 Query: 132 IRSISIASQCPTAGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYDP---LYHP 188 + I + G +VSGWG R P L + + +V C K Y P Sbjct: 120 VMPICLPEGPQQEGAMVIVSGWGKQFLQRFPETLMEIEIPIVDHSTCQKAYAPLKKKVTR 179 Query: 189 SMFCAGGGHDQKDSCNGDSGGPLIC------NGYLQGLVSFGKAPCGQVGVPGVYTNLCK 242 M CAG KD+C GDSGGP++ YL G VS+G CG+ GVY+ + Sbjct: 180 DMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGD-DCGKKDRYGVYSYIHH 238 Query: 243 FTEWIEKTV 251 +WI++ Sbjct: 239 NKDWIQRVT 247 >4KKD-A nrPDB Length = 433 Score = 237 bits (606), Expect = 3e-63, Method: Composition-based stats. Identities = 75/269 (27%), Positives = 117/269 (43%), Gaps = 49/269 (18%) Query: 30 QIINGEDCSPHSQPWQAALVMEN-------ELFCSGVLVHPQWVLSAAHCFQNSY----- 77 +II G + P PWQA +V+E+ + F SG L+ W+L+AAH ++ Sbjct: 154 RIIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTV 213 Query: 78 --------TIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSES 129 T+ LGLH + + G+ A+ V HP++N +D+ L++L E V Sbjct: 214 IPVSKEHVTVYLGLH--DVRDKSGAVNSSAARVVLHPDFNIQNYNHDIALVQLQEPVPLG 271 Query: 130 DTIRSISIA---SQCPTAGNSCLVSGWGLLANG------------RMPTVLQCVNVSVVS 174 + + + + P LV+GWG+ + VLQ V + VV Sbjct: 272 PHVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVP 331 Query: 175 EEVCSKLYDPL-----YHPSMFCAGGGHDQKDSCNGDSGGPLI------CNGYLQGLVSF 223 C Y+ +MFCAG KD+C GDSG + +QGLVS+ Sbjct: 332 HAECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGEAFVIFDDLSQRWVVQGLVSW 391 Query: 224 -GKAPCGQVGVPGVYTNLCKFTEWIEKTV 251 G CG V GVYT + + +W+ + + Sbjct: 392 GGPEECGSKQVYGVYTKVSNYVDWVWEQM 420 >5XRF-A nrPDB Length = 242 Score = 237 bits (605), Expect = 4e-63, Method: Composition-based stats. Identities = 78/236 (33%), Positives = 125/236 (52%), Gaps = 9/236 (3%) Query: 26 GSCSQIINGEDCSPHSQPWQAALVMEN--ELFCSGVLVHPQWVLSAAHCFQNSYTIGLGL 83 S +I G +C + + AA C+G L+H +WVL+AAHC++ I LG+ Sbjct: 2 KSSELVIGGNECDTNEHRFLAAFFTSRPWTFQCAGTLIHEEWVLAAAHCYKRGLNIYLGM 61 Query: 84 H--SLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQC 141 H S++ D E +E + + D++L+KL++ VS S I +S+ S Sbjct: 62 HNQSIQFDDEQRRYAIEEHYYRCDEKLTK--WEKDVVLLKLNKPVSNSTHIAPLSLPSSP 119 Query: 142 PTAGNSCLVSGWGLLANGR--MPTVLQCVNVSVVSEEVCSKLYDPLY-HPSMFCAGGGHD 198 P+ G+ C V GWG++++ + +P V C N+++++ C Y + + CAG Sbjct: 120 PSIGSVCRVMGWGIMSSTKDILPDVPHCANINLLNYMECVAHYPDVPETTRLLCAGVLEG 179 Query: 199 QKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 D+CN DSGGPLIC+G QG+V FGK PC Q PG+YT + + +WI+ + Sbjct: 180 GIDTCNQDSGGPLICDGQFQGIVFFGKYPCAQPNKPGLYTRVSNYNDWIQNIIAGK 235 >2XXL-A nrPDB Length = 408 Score = 237 bits (605), Expect = 4e-63, Method: Composition-based stats. Identities = 76/261 (29%), Positives = 119/261 (45%), Gaps = 35/261 (13%) Query: 28 CSQIINGEDCSPHSQPWQAALVM----ENELFCSGVLVHPQWVLSAAHCF----QNSYTI 79 ++ NG + S+PW A L E+ C G ++ +++L+AAHC + Y I Sbjct: 116 SQRVSNGYEVKLSSRPWMALLRYQQFGESRFLCGGAMISERYILTAAHCVHGLQNDLYEI 175 Query: 80 GLGLHSLEADQE-----------PGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSE 128 LG H + +++ P V + H +Y+ + +D+ L+KL+ SV Sbjct: 176 RLGEHRISTEEDCRQQGRKKKCAPPVVNVGIEKHLIHEKYDARHIMHDIALLKLNRSVPF 235 Query: 129 SDTIRSISIA-----SQCPTAGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYD 183 I+ I + + ++ V+GWG NG VL NV + CS+ Y Sbjct: 236 QKHIKPICLPITDELKEKAEQISTYFVTGWGTTENGSSSDVLLQANVPLQPRSACSQAYR 295 Query: 184 PLYHPSMFCAGGGHDQKDSCNGDSGGPLIC----------NGYLQGLVSFGKAPCGQVGV 233 S C GGG Q DSC GDSGGPL G+VS G CGQ+ + Sbjct: 296 RAVPLSQLCVGGGDLQ-DSCKGDSGGPLQAPAQYLGEYAPKMVEFGIVSQGVVTCGQISL 354 Query: 234 PGVYTNLCKFTEWIEKTVQAS 254 PG+YTN+ ++ +WI T+ ++ Sbjct: 355 PGLYTNVGEYVQWITDTMASN 375 >4BXW-A nrPDB Length = 423 Score = 236 bits (603), Expect = 6e-63, Method: Composition-based stats. Identities = 66/247 (26%), Positives = 112/247 (45%), Gaps = 21/247 (8%) Query: 28 CSQIINGEDCSPHSQPWQAALVM-ENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSL 86 +I+NG DC PWQAALV + +FC G ++ P +VL+AAHC + TI + + + Sbjct: 167 DIRIVNGMDCKLGECPWQAALVDEKEGVFCGGTILSPIYVLTAAHCINETETISVVVGEI 226 Query: 87 EADQEPGSQMVEASLSVRHPEYNRPL---------LANDLMLIKLDESVSESDTIRSISI 137 + + ++ H ++ P D+ +I++ + S+ + + Sbjct: 227 DKSRIETGPLLSVDKIYVHKKFVPPQKAYKFDLAAYDYDIAIIQMKTPIQFSENVVPACL 286 Query: 138 ASQCPTAG-----NSCLVSGWGLL-ANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMF 191 + + +VSG+G + G L+ + V V C + P+MF Sbjct: 287 PTADFANQVLMKQDFGIVSGFGRIVEKGPKSKTLKVLKVPYVDRHTCMVSSETPITPNMF 346 Query: 192 CAGGGHDQKDSCNGDSGGPLIC----NGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWI 247 CAG +D+C GDSGGP ++ G+VS G+ C + G G YT L KF WI Sbjct: 347 CAGYDTLPRDACQGDSGGPHTTVYRDTHFITGIVSSGEG-CARNGKYGNYTKLSKFIPWI 405 Query: 248 EKTVQAS 254 ++ ++ Sbjct: 406 KRIMRQK 412 >2ZKS-A nrPDB Length = 240 Score = 236 bits (603), Expect = 6e-63, Method: Composition-based stats. Identities = 85/235 (36%), Positives = 121/235 (51%), Gaps = 15/235 (6%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNS---YTIGLGLHSLE 87 II G + PHS+P+ A+L C GVLVHP+WVL+AAHC + LGLH+L+ Sbjct: 1 IIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTAAHCLAQRMAQLRLVLGLHTLD 60 Query: 88 ADQEPGSQMVEASLSVRHPEYNR-PLLANDLMLIKLDESVSESDTIRSISIAS--QCPTA 144 +++HP Y P L NDL L++LD V S TIR +++ S Q A Sbjct: 61 ----SPGLTFHIKAAIQHPRYKPVPALENDLALLQLDGKVKPSRTIRPLALPSKRQVVAA 116 Query: 145 GNSCLVSGWGLLA-NGRMPTVLQCVNVSVVSEEVC--SKLYDPLYHPSMFCAGGGHDQKD 201 G C ++GWGL GR+ VL+ +++ V+ +C S+ ++ PSM C + Sbjct: 117 GTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRFWNGSLSPSMVCLAADSKDQA 176 Query: 202 SCNGDSGGPLIC--NGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 C GDSGGPL+C L G++SF C + P V T + + WI K S Sbjct: 177 PCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVATAVAPYVSWIRKVTGRS 231 >1ZJK-A nrPDB Length = 403 Score = 236 bits (602), Expect = 8e-63, Method: Composition-based stats. Identities = 67/246 (27%), Positives = 107/246 (43%), Gaps = 24/246 (9%) Query: 27 SCSQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCF----QNSYTIGLG 82 + QI G+ P PWQ ++ +G L++ WVL+AAH ++ + + Sbjct: 158 TGGQIYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNWVLTAAHAVYEQKHDASALDIR 215 Query: 83 LHSLEADQEPGSQMVEASLSVRHPEY-NRPLLANDLMLIKLDESVSESDTIRSISIASQC 141 + +L+ +Q H Y + ND+ LIKL+ V + I I + + Sbjct: 216 MGTLKRLSPHYTQAWS-EAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPICLPRKE 274 Query: 142 PT----AGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYD------PLYHPSMF 191 + SGWGL G + L V++ +V + C+ Y+ +M Sbjct: 275 AESFMRTDDIGTASGWGLTQRGFLARNLMYVDIPIVDHQKCTAAYEKPPYPRGSVTANML 334 Query: 192 CAGGGHDQKDSCNGDSGGPLIC------NGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTE 245 CAG KDSC GDSGG L+ ++ G+VS+G CG+ G GVYT + + Sbjct: 335 CAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVYTKVINYIP 394 Query: 246 WIEKTV 251 WIE + Sbjct: 395 WIENII 400 >2V35-A nrPDB Length = 240 Score = 236 bits (602), Expect = 1e-62, Method: Composition-based stats. Identities = 66/242 (27%), Positives = 109/242 (45%), Gaps = 20/242 (8%) Query: 31 IINGEDCSPHSQPWQAALVMENE----LFCSGVLVHPQWVLSAAHCFQN--SYTIGLGLH 84 ++ G + +S P Q +L + C G L+ WV++AAHC ++ + +G H Sbjct: 1 VVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDRELTFRVVVGEH 60 Query: 85 SLEADQEPGSQMVEASLSVRHPEYNRPLL--ANDLMLIKLDESVSESDTIRSISIASQCP 142 +L + Q V V HP +N + D+ L++L +SV+ + ++ + Sbjct: 61 NLNQND-GTEQYVGVQKIVVHPYWNTDDVAAGYDIALLRLAQSVTLNSYVQLGVLPRAGT 119 Query: 143 --TAGNSCLVSGWGLL-ANGRMPTVLQCVNVSVVSEEVCSKL--YDPLYHPSMFCAGGGH 197 + C ++GWGL NG++ LQ + V +CS + SM CAGG Sbjct: 120 ILANNSPCYITGWGLTRTNGQLAQTLQQAYLPTVDYAICSSSSYWGSTVKNSMVCAGG-D 178 Query: 198 DQKDSCNGDSGGPLIC--NGY--LQGLVSFGKA-PCGQVGVPGVYTNLCKFTEWIEKTVQ 252 + C GDSGGPL C NG + G+ SF C P V+T + + WI + Sbjct: 179 GVRSGCQGDSGGPLHCLVNGQYAVHGVTSFVSRLGCNVTRKPTVFTRVSAYISWINNVIA 238 Query: 253 AS 254 ++ Sbjct: 239 SN 240 >1A5I-A nrPDB Length = 265 Score = 235 bits (601), Expect = 1e-62, Method: Composition-based stats. Identities = 72/250 (28%), Positives = 112/250 (44%), Gaps = 33/250 (13%) Query: 33 NGEDCSPHSQPWQAALVMENE------LFCSGVLVHPQWVLSAAHCFQNSY-----TIGL 81 G S PWQAA+ +N C G+L+ WVL+AAHCFQ SY + L Sbjct: 16 GGLFTDITSHPWQAAIFAQNRRSSGERFLCGGILISSCWVLTAAHCFQESYLPDQLKVVL 75 Query: 82 GLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLD----ESVSESDTIRSISI 137 G + Q + + H E++ ND+ L++L + ESD++R+I + Sbjct: 76 G-RTYRVKPGEEEQTFKVKKYIVHKEFDDDTYNNDIALLQLKSDSPQCAQESDSVRAICL 134 Query: 138 ASQCPTAG--NSCLVSGWGLLANGR--MPTVLQCVNVSVVSEEVCSK--LYDPLYHPSMF 191 C +SG+G + L+ +V + C+ L++ +M Sbjct: 135 PEANLQLPDWTECELSGYGKHKSSSPFYSEQLKEGHVRLYPSSRCAPKFLFNKTVTNNML 194 Query: 192 CAGGGHDQK------DSCNGDSGGPLIC----NGYLQGLVSFGKAPCGQVGVPGVYTNLC 241 CAG + D+C GDSGGPL+C + L G++S+G CG+ VPGVYT + Sbjct: 195 CAGDTRSGEIYPNVHDACQGDSGGPLVCMNDNHMTLLGIISWGVG-CGEKDVPGVYTKVT 253 Query: 242 KFTEWIEKTV 251 + WI + Sbjct: 254 NYLGWIRDNM 263 >4FXG-H nrPDB Length = 242 Score = 235 bits (601), Expect = 1e-62, Method: Composition-based stats. Identities = 65/242 (26%), Positives = 105/242 (43%), Gaps = 24/242 (9%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCF----QNSYTIGLGLHSL 86 I G+ P PWQ ++ +G L++ WVL+AAH ++ + + + +L Sbjct: 1 IYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNWVLTAAHAVYEQKHDASALDIRMGTL 58 Query: 87 EADQEPGSQMVEASLSVRHPEY-NRPLLANDLMLIKLDESVSESDTIRSISIASQCPT-- 143 + +Q H Y + ND+ LIKL+ V + I I + + Sbjct: 59 KRLSPHYTQAWS-EAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPICLPRKEAESF 117 Query: 144 --AGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYD------PLYHPSMFCAGG 195 + SGWGL G + L V++ +V + C+ Y+ +M CAG Sbjct: 118 MRTDDIGTASGWGLTQRGFLARNLMYVDIPIVDHQKCTAAYEKPPYPRGSVTANMLCAGL 177 Query: 196 GHDQKDSCNGDSGGPLIC------NGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEK 249 KDSC GD+GG L+ ++ G+VS+G CG+ G GVYT + + WIE Sbjct: 178 ESGGKDSCRGDAGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVYTKVINYIPWIEN 237 Query: 250 TV 251 + Sbjct: 238 II 239 >2R0L-A nrPDB Length = 248 Score = 235 bits (599), Expect = 2e-62, Method: Composition-based stats. Identities = 78/242 (32%), Positives = 121/242 (50%), Gaps = 23/242 (9%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCF-----QNSYTIGLGLHS 85 II G P S PW AA+ + + FC+G LVH WV+SAAHCF ++S ++ LG H Sbjct: 1 IIGGSSSLPGSHPWLAAIYIGDS-FCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHF 59 Query: 86 LEADQEPGSQMVEASLSVRHPEYNRPL-LANDLMLIKLDES----VSESDTIRSISIAS- 139 +Q + + Y+ +DL+LI+L + + S ++ I + Sbjct: 60 FNR-TTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLPEP 118 Query: 140 -QCPTAGNSCLVSGWGLLANG--RMPTVLQCVNVSVVSEEVCSK--LYDPLYHPSMFCAG 194 AG+ C ++GWG L + L+ V +V++ CS +Y P+M CAG Sbjct: 119 GSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNMLCAG 178 Query: 195 GGHDQKDSCNGDSGGPLICNG----YLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKT 250 + D+C GDSGGPL C YL G++S+G CG++ PGVYT + + +WI Sbjct: 179 YFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDG-CGRLHKPGVYTRVANYVDWINDR 237 Query: 251 VQ 252 ++ Sbjct: 238 IR 239 >5O32-I nrPDB Length = 244 Score = 234 bits (597), Expect = 3e-62, Method: Composition-based stats. Identities = 71/233 (30%), Positives = 111/233 (47%), Gaps = 19/233 (8%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 I+ G+ PWQ A+ + + C G+ + W+L+AAHC + S T + + D Sbjct: 1 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 60 Query: 91 -EPGSQMV---EASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPT--- 143 P + + + H YN ND+ LI++ + ++ D SI + P Sbjct: 61 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 120 Query: 144 ---AGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHP-SMFCAGGGHDQ 199 ++C+VSGWG + LQ V ++S CSK Y ++ M CAG Sbjct: 121 LFQPNDTCIVSGWGREKDNERVFSLQWGEVKLISN--CSKFYGNRFYEKEMECAGTYDGS 178 Query: 200 KDSCNGDSGGPLICNG-----YLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWI 247 D+C GDSGGPL+C Y+ G+VS+G+ CG+ PGVYT + + +WI Sbjct: 179 IDACKGDSGGPLVCMDANNVTYVWGVVSWGEN-CGKPEFPGVYTKVANYFDWI 230 >5UBM-A nrPDB Length = 252 Score = 228 bits (583), Expect = 1e-60, Method: Composition-based stats. Identities = 69/254 (27%), Positives = 108/254 (42%), Gaps = 37/254 (14%) Query: 30 QIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSY--TIGLGLHSLE 87 +II G D + PWQ + + G L++ WVL+AAH + + T+ +G S++ Sbjct: 1 RIIGGSDADIKNFPWQVFF---DNPWAGGALINEYWVLTAAHVVEGNREPTMYVGSTSVQ 57 Query: 88 ADQEPGSQMVEASLSVRHPEYN-------RPLLANDLMLIKLDESVSESDTIRSISIASQ 140 + S+M+ HP + R ND+ L++L + V T+ I + Sbjct: 58 TSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLPGT 117 Query: 141 CPT----AGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLY---------DPLYH 187 G+ L+SGWG L+ + V C ++ ++ Sbjct: 118 SSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKVEKPTADAEAYVFT 177 Query: 188 PSMFCAGGGHDQKDSCNGDSGGPLICNG-------YLQGLVSFGKAPCGQVGVPGVYTNL 240 P+M CAGG DSC GDSGG Y GLVS+G Q G G+YT + Sbjct: 178 PNMICAGG-EKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGP----QCGTYGLYTRV 232 Query: 241 CKFTEWIEKTVQAS 254 + +WI KT+Q + Sbjct: 233 KNYVDWIMKTMQEN 246 >1ELV-A nrPDB Length = 333 Score = 226 bits (578), Expect = 6e-60, Method: Composition-based stats. Identities = 69/260 (26%), Positives = 108/260 (41%), Gaps = 37/260 (14%) Query: 24 VSGSCSQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSY--TIGL 81 +II G D + PWQ + + G L++ WVL+AAH + + T+ + Sbjct: 76 PFEEKQRIIGGSDADIKNFPWQVFF---DNPWAGGALINEYWVLTAAHVVEGNREPTMYV 132 Query: 82 GLHSLEADQEPGSQMVEASLSVRHPEYN-------RPLLANDLMLIKLDESVSESDTIRS 134 G S++ + S+M+ HP + R ND+ L++L + V T+ Sbjct: 133 GSTSVQTSRLAKSKMLTPEHVFIHPGWKLLAVPEGRTNFDNDIALVRLKDPVKMGPTVSP 192 Query: 135 ISIASQCPT----AGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLY-------- 182 I + G+ L+SGWG L+ + V C ++ Sbjct: 193 ICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKVEKPTADA 252 Query: 183 -DPLYHPSMFCAGGGHDQKDSCNGDSGGPLICNG-------YLQGLVSFGKAPCGQVGVP 234 ++ P+M CAGG DSC GDSGG Y GLVS+G Q G Sbjct: 253 EAYVFTPNMICAGG-EKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGP----QCGTY 307 Query: 235 GVYTNLCKFTEWIEKTVQAS 254 G+YT + + +WI KT+Q + Sbjct: 308 GLYTRVKNYVDWIMKTMQEN 327 >1FON-A nrPDB Length = 240 Score = 225 bits (574), Expect = 1e-59, Method: Composition-based stats. Identities = 78/243 (32%), Positives = 115/243 (47%), Gaps = 24/243 (9%) Query: 33 NGEDCSPHSQPWQAALVMEN----ELFCSGVLVHPQWVLSAAHCFQNS--YTIGLGLHSL 86 NGED P+S WQ +L E C G L+ P WV++A HC S Y + LG + Sbjct: 1 NGEDAVPYSWSWQVSLQYEKDGAFHHTCGGSLIAPDWVVTAGHCISTSRTYQVVLGEYDR 60 Query: 87 EADQEPGSQMVEAS--LSVRHPEYNRPLL--ANDLMLIKLDESVSESDTIRSISIASQCP 142 E Q++ + HP +N + ND+ L+KL S D ++ ++ Sbjct: 61 SVL-EGSEQVIPINAGDLFVHPLWNSNCVACGNDIALVKLSRSAQLGDKVQLANLPPAGD 119 Query: 143 TAGN--SCLVSGWGLL-ANGRMPTVLQCVNVSVVSEEVCSK--LYDPLYHPSMFCAGGGH 197 N C +SGWG L G +P LQ + V E CS+ + +M CAGG Sbjct: 120 ILPNEAPCYISGWGRLYTGGPLPDKLQQALLPTVDYEHCSQWDWWGITVKKTMVCAGG-- 177 Query: 198 DQKDSCNGDSGGPLIC-----NGYLQGLVSFGKA-PCGQVGVPGVYTNLCKFTEWIEKTV 251 D + CNGDSGGPL C + + G+ SF A C + P V+T + F +WI++T+ Sbjct: 178 DTRSGCNGDSGGPLNCPAADGSWQVHGVTSFVSAFGCNTIKKPTVFTRVSAFIDWIDETI 237 Query: 252 QAS 254 ++ Sbjct: 238 ASN 240 >1ELT-A nrPDB Length = 236 Score = 224 bits (572), Expect = 3e-59, Method: Composition-based stats. Identities = 66/239 (27%), Positives = 110/239 (46%), Gaps = 21/239 (8%) Query: 31 IINGEDCSPHSQPWQAALVMENE----LFCSGVLVHPQWVLSAAHCFQN--SYTIGLGLH 84 ++ G P+S PWQ +L ++ C G L+ WV++AAHC + ++ + LG H Sbjct: 1 VVGGRVAQPNSWPWQISLQYKSGSSYYHTCGGSLIRQGWVMTAAHCVDSARTWRVVLGEH 60 Query: 85 SLEADQEPGSQMVEASLSVRHPEYNRPLL--ANDLMLIKLDESVSESDTIRSISIAS--Q 140 +L E Q++ + H +N + D+ L++L+ S + ++ ++ Q Sbjct: 61 NLNT-NEGKEQIMTVNSVFIHSGWNSDDVAGGYDIALLRLNTQASLNSAVQLAALPPSNQ 119 Query: 141 CPTAGNSCLVSGWGLL-ANGRMPTVLQCVNVSVVSEEVCSK--LYDPLYHPSMFCAGGGH 197 N C ++GWG G + L+ + V CS + +M CAGGG Sbjct: 120 ILPNNNPCYITGWGKTSTGGPLSDSLKQAWLPSVDHATCSSSGWWGSTVKTTMVCAGGGA 179 Query: 198 DQKDSCNGDSGGPLIC--NG--YLQGLVSFG-KAPCGQVGVPGVYTNLCKFTEWIEKTV 251 + CNGDSGGPL C NG Y+ G+ SF + C P V+T + + W+ + Sbjct: 180 N--SGCNGDSGGPLNCQVNGSYYVHGVTSFVSSSGCNASKKPTVFTRVSAYISWMNGIM 236 >1AE5-A nrPDB Length = 225 Score = 222 bits (567), Expect = 1e-58, Method: Composition-based stats. Identities = 71/228 (31%), Positives = 110/228 (48%), Gaps = 18/228 (7%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNS----YTIGLGLHSL 86 I+ G P P+ A++ + FC G L+H ++V++AA CFQ+ T+ LG + L Sbjct: 1 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 60 Query: 87 EADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESD--TIRSISIASQCPTA 144 + Q S S+ Y+ NDLML++LD + + TI + + + A Sbjct: 61 RRRERQSRQTFSIS-SMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEA 119 Query: 145 GNSCLVSGWGL-LANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSC 203 G C V+GWG + GR+ + VNV+V E+ C P+ C G + C Sbjct: 120 GTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC--------RPNNVCTGVLTRRGGIC 171 Query: 204 NGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 251 NGD G PL+C G G+ SF PCG+ P +T + F +WI+ + Sbjct: 172 NGDGGTPLVCEGLAHGVASFSLGPCGRG--PDFFTRVALFRDWIDGVL 217 >4J1Y-A nrPDB Length = 397 Score = 222 bits (566), Expect = 1e-58, Method: Composition-based stats. Identities = 68/260 (26%), Positives = 108/260 (41%), Gaps = 37/260 (14%) Query: 24 VSGSCSQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSY--TIGL 81 ++ I G D + PWQ + + G L++ WVL+AAH + + T+ + Sbjct: 140 PFEEKARAIGGSDADIKNFPWQVFF---DNPWAGGALINEYWVLTAAHVVEGNREPTMYV 196 Query: 82 GLHSLEADQEPGSQMVEASLSVRHPEYN-------RPLLANDLMLIKLDESVSESDTIRS 134 G S++ + S+M+ HP + R ND+ L++L + V T+ Sbjct: 197 GSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSP 256 Query: 135 ISIASQCPT----AGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLY-------- 182 I + G+ L+SGWG L+ + V C ++ Sbjct: 257 ICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKVEKPTADA 316 Query: 183 -DPLYHPSMFCAGGGHDQKDSCNGDSGGPLICNG-------YLQGLVSFGKAPCGQVGVP 234 ++ P+M CAGG DSC GDSGG Y GLVS+G Q G Sbjct: 317 EAYVFTPNMICAGG-EKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGP----QCGTY 371 Query: 235 GVYTNLCKFTEWIEKTVQAS 254 G+YT + + +WI KT+Q + Sbjct: 372 GLYTRVKNYVDWIMKTMQEN 391 >1EQ9-A nrPDB Length = 222 Score = 221 bits (564), Expect = 2e-58, Method: Composition-based stats. Identities = 63/226 (27%), Positives = 102/226 (45%), Gaps = 7/226 (3%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTI-GLGLHSLEAD 89 I+ G+D P+Q +L + C ++ VL+AAHC + L +H Sbjct: 1 IVGGKDAPVGKYPYQVSLRLSGSHRCGASILDNNNVLTAAHCVDGLSNLNRLKVHVGTNY 60 Query: 90 QEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPT-AGNSC 148 + + +V + Y+ LL ND+ L+ L + +D ++ I +++ N C Sbjct: 61 LSESGDVYDVEDAVVNKNYDDFLLRNDVALVHLTNPIKFNDLVQPIKLSTNDEDLESNPC 120 Query: 149 LVSGWGLLA-NGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDS 207 ++GWG G P LQ + + V ++ C + S C + +C+GDS Sbjct: 121 TLTGWGSTRLGGNTPNALQEIELIVHPQKQCERD-QWRVIDSHICT-LTKRGEGACHGDS 178 Query: 208 GGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQA 253 GGPL+ NG G+VSFG PC G P VYT + F WI ++ Sbjct: 179 GGPLVANGAQIGIVSFGS-PCAL-GEPDVYTRVSSFVSWINANLKK 222 >2OLG-A nrPDB Length = 278 Score = 221 bits (564), Expect = 2e-58, Method: Composition-based stats. Identities = 78/260 (30%), Positives = 123/260 (47%), Gaps = 37/260 (14%) Query: 28 CSQIINGEDCSPHSQPWQAALVMEN-----ELFCSGVLVHPQWVLSAAHCFQNSY----- 77 +I+NG+D P PW A + +N + C G L++ +++++AAHC Sbjct: 20 ADKILNGDDTVPEEFPWTAMIGYKNSSNFEQFACGGSLINNRYIVTAAHCVAGRVLRVVG 79 Query: 78 ---TIGLGLHSLEADQE----------PGSQMVEASLSVRHPEYNRPLLA--NDLMLIKL 122 + LG + D + + +++HP+Y +D+ LI+L Sbjct: 80 ALNKVRLGEWNTATDPDCYGAVRVCVPDKPIDLGIEETIQHPDYVDGSKDRYHDIALIRL 139 Query: 123 DESVSESDTIRSISI--ASQCPTAGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSK 180 + V ++ IR + + ++ G V GWG G+ T+ Q + V VV E C+K Sbjct: 140 NRQVEFTNYIRPVCLPQPNEEVQVGQRLTVVGWGRTETGQYSTIKQKLAVPVVHAEQCAK 199 Query: 181 LYDP---LYHPSMFCAGGGHDQKDSCNGDSGGPLICNG-----YLQGLVSFGKAPCGQVG 232 + S CAGG KDSC GDSGGPL+ +L+GLVSFG A CG G Sbjct: 200 TFGAAGVRVRSSQLCAGG-EKAKDSCGGDSGGPLLAERANQQFFLEGLVSFG-ATCGTEG 257 Query: 233 VPGVYTNLCKFTEWIEKTVQ 252 PG+YT + K+ +WIE ++ Sbjct: 258 WPGIYTKVGKYRDWIEGNIR 277 >1PPF-E nrPDB Length = 218 Score = 218 bits (555), Expect = 2e-57, Method: Composition-based stats. Identities = 71/229 (31%), Positives = 110/229 (48%), Gaps = 18/229 (7%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIG----LGLHSL 86 I+ G PH+ P+ +L + FC L+ P +V+SAAHC N LG H+L Sbjct: 1 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 60 Query: 87 EADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGN 146 EP Q+ Y+ L ND+++++L+ S + + ++ + +Q GN Sbjct: 61 SRR-EPTRQVFAVQRIF-ENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGN 118 Query: 147 --SCLVSGWGLLANGR-MPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSC 203 CL GWGLL R + +VLQ +NV+VV+ +C + S C Q C Sbjct: 119 GVQCLAMGWGLLGRNRGIASVLQELNVTVVT-SLCRR--------SNVCTLVRGRQAGVC 169 Query: 204 NGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 252 GDSG PL+CNG + G+ SF + C P + + +F WI+ +Q Sbjct: 170 FGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 218 >5KWM-A nrPDB Length = 230 Score = 217 bits (554), Expect = 3e-57, Method: Composition-based stats. Identities = 66/229 (28%), Positives = 102/229 (44%), Gaps = 11/229 (4%) Query: 31 IINGEDCSPHSQPWQAALVM-ENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEAD 89 I+ GED + P+ ALV + + FC G L P V++AAHC S + + S Sbjct: 1 IVGGEDANVQDHPFTVALVTPDGQQFCGGTLAAPNKVVTAAHCTVGSQPADINVVSGRTV 60 Query: 90 QEPGSQMV-EASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQC---PTAG 145 V + + HPEY D+ ++ L+ V E I +A Sbjct: 61 MSSNEGTVSKVTNVWVHPEYQDAAKGFDVSVLTLEAPVKE----APIELAKADDAGYAPD 116 Query: 146 NSCLVSGWGLL-ANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCN 204 + + GWG G+ LQ V V S++ C + Y +M CAG D+C Sbjct: 117 TAATILGWGNTSEGGQQADHLQKATVPVNSDDTCKQAYGEYTPDAMVCAGVPEGGVDTCQ 176 Query: 205 GDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQA 253 GDSGGP++ N L G+ S+G+ C + G PGVY + + + + + + A Sbjct: 177 GDSGGPMVVNNKLIGVTSWGEG-CARPGKPGVYARVGAYYDVLMEQINA 224 >4X0L-C nrPDB Length = 259 Score = 215 bits (548), Expect = 2e-56, Method: Composition-based stats. Identities = 68/262 (25%), Positives = 114/262 (43%), Gaps = 41/262 (15%) Query: 24 VSGSCSQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGL 83 + +I+ G + S PWQA +V + L L++ QW+L+ A + + Sbjct: 8 PANPVQRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTA----KNLFLNHSE 63 Query: 84 HSLEADQEPG-------SQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSIS 136 ++ D P Q+VE V HP Y++ D+ LIKL + VS ++ + I Sbjct: 64 NATAKDIAPTLTLYVGKKQLVEIEKVVLHPNYSQV----DIGLIKLKQKVSVNERVMPIC 119 Query: 137 IASQC-PTAGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYD------------ 183 + S+ G VSGWG AN + L+ V + V ++ C + Y+ Sbjct: 120 LPSKDYAEVGRVGYVSGWGRNANFKFTDHLKYVMLPVADQDQCIRHYEGSTVPEKKTPKS 179 Query: 184 -----PLYHPSMFCAGGGHDQKDSCNGDSGGPLICN------GYLQGLVSFGKAPCGQVG 232 P+ + FCAG Q+D+C GD+G + Y G++SF K+ C Sbjct: 180 PVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDKS-CAVA- 237 Query: 233 VPGVYTNLCKFTEWIEKTVQAS 254 GVY + +W++KT+ + Sbjct: 238 EYGVYVKVTSIQDWVQKTIAEN 259 >2B9L-A nrPDB Length = 394 Score = 215 bits (547), Expect = 2e-56, Method: Composition-based stats. Identities = 70/263 (26%), Positives = 109/263 (41%), Gaps = 36/263 (13%) Query: 26 GSCSQIINGE-DCSPHSQPWQAALVMEN--------ELFCSGVLVHPQWVLSAAHCFQ-- 74 G +I + PW A++ N +L C G L+ P VL+ AHC Sbjct: 125 GLDFKITGQTNEAEYGEFPWMVAVLKANVIPGSGEEQLVCGGSLIAPSVVLTGAHCVNSY 184 Query: 75 ----NSYTIGLGLHSLEADQEP-GSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSES 129 ++ I G ++E Q + + H +N + ND+ L+ LD + ++ Sbjct: 185 QSNLDAIKIRAGEWDTLTEKERLPYQERKIRQVIIHSNFNPKTVVNDVALLLLDRPLVQA 244 Query: 130 DTIRSISIASQCPTAGNS-CLVSGWGLLANG---RMPTVLQCVNVSVVSEEVCSKLYDP- 184 D I +I + Q ++ C SGWG G R +L+ + + V + C Sbjct: 245 DNIGTICLPQQSQIFDSTECFASGWGKKEFGSRHRYSNILKKIQLPTVDRDKCQADLRNT 304 Query: 185 ------LYHPSMFCAGGGHDQKDSCNGDSGGPLICNG-------YLQGLVSFGKAPCGQV 231 + + CAGG KD+C GD G PL C G+V++G CG Sbjct: 305 RLGLKFVLDQTFVCAGG-EQGKDTCTGDGGSPLFCPDPRNPSRYMQMGIVAWGIG-CGDE 362 Query: 232 GVPGVYTNLCKFTEWIEKTVQAS 254 VPGVY N+ F WI++ +QA Sbjct: 363 NVPGVYANVAHFRNWIDQEMQAK 385 >4WJG-C nrPDB Length = 315 Score = 214 bits (546), Expect = 2e-56, Method: Composition-based stats. Identities = 68/262 (25%), Positives = 114/262 (43%), Gaps = 41/262 (15%) Query: 24 VSGSCSQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGL 83 + +I+ G + S PWQA +V + L L++ QW+L+ A + + Sbjct: 64 PANPVQRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTA----KNLFLNHSE 119 Query: 84 HSLEADQEPG-------SQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSIS 136 ++ D P Q+VE V HP Y++ D+ LIKL + VS ++ + I Sbjct: 120 NATAKDIAPTLTLYVGKKQLVEIEKVVLHPNYSQV----DIGLIKLKQKVSVNERVMPIC 175 Query: 137 IASQC-PTAGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYD------------ 183 + S+ G VSGWG AN + L+ V + V ++ C + Y+ Sbjct: 176 LPSKDYAEVGRVGYVSGWGRNANFKFTDHLKYVMLPVADQDQCIRHYEGSTVPEKKTPKS 235 Query: 184 -----PLYHPSMFCAGGGHDQKDSCNGDSGGPLICN------GYLQGLVSFGKAPCGQVG 232 P+ + FCAG Q+D+C GD+G + Y G++SF K+ C Sbjct: 236 PVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDKS-CAVA- 293 Query: 233 VPGVYTNLCKFTEWIEKTVQAS 254 GVY + +W++KT+ + Sbjct: 294 EYGVYVKVTSIQDWVQKTIAEN 315 >4LK4-A nrPDB Length = 357 Score = 211 bits (537), Expect = 3e-55, Method: Composition-based stats. Identities = 70/248 (28%), Positives = 121/248 (48%), Gaps = 26/248 (10%) Query: 24 VSGSCSQIINGEDCSPHSQPWQAALVMEN-----ELFCSGVLVHPQWVLSAAHCF--QNS 76 + S+IING + + P ALV FC G + ++VL+AAHCF +++ Sbjct: 4 TADISSRIINGSNANSAEWPSIVALVKRGADAYQGQFCGGSFLGGRYVLTAAHCFDSRSA 63 Query: 77 YTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSIS 136 ++ + + + + + + + A RH Y+ L ND+ +++L + + ++ +I+ Sbjct: 64 ASVDVIIGAYDLNNSSQGERIAAQKIYRHLSYSPSNLLNDIAIVELAQ----TSSLPAIT 119 Query: 137 IASQCPTAG----NSCLVSGWGLLANGRMP---TVLQCVNVSVVSEEVCSKLYDPLY--- 186 +A V+GWG+ + P +LQ V+V +VS+ +C + Sbjct: 120 LAGPATRTSLPALTPLTVAGWGITVQSKPPQFTPILQEVDVDLVSQSLCQIVMQHGISSD 179 Query: 187 -HPSMFCAGGGHDQKDSCNGDSGGPLICN-GYLQ-GLVSFGKAPCGQVGVPGVYTNLCKF 243 + + FCA KDSC GD+GGP++ G Q G+VS+G C + G GVYTN+ F Sbjct: 180 PNSTNFCAARLT--KDSCQGDAGGPIVVKTGREQLGIVSWGDEQCAKTGTYGVYTNVSYF 237 Query: 244 TEWIEKTV 251 +WI K Sbjct: 238 RDWITKHT 245 >4F4O-C nrPDB Length = 347 Score = 211 bits (537), Expect = 3e-55, Method: Composition-based stats. Identities = 65/262 (24%), Positives = 108/262 (41%), Gaps = 41/262 (15%) Query: 24 VSGSCSQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGL 83 +I+ G + S PWQA ++ + L L++ QW+L+ A + +G Sbjct: 96 PVDQVQRIMGGSLDAKGSFPWQAKMISHHNLTSGATLINEQWLLTTA----KNLRLGHKN 151 Query: 84 HSLEADQEPG-------SQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSIS 136 + D P Q VE + HP+ + D+ LIKL + V ++ + I Sbjct: 152 DTKAKDIAPTLRLYVGKKQEVEIEKVIFHPDNSTV----DIGLIKLKQKVPVNERVMPIC 207 Query: 137 IASQCP-TAGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYD------------ 183 + S+ G VSGWG AN L+ V + V +E C + Y+ Sbjct: 208 LPSKDYVNVGLVGYVSGWGRNANLNFTEHLKYVMLPVADQEKCVQYYEGSTVPEKKTPKS 267 Query: 184 -----PLYHPSMFCAGGGHDQKDSCNGDSGGPLICN------GYLQGLVSFGKAPCGQVG 232 P+ + FCAG Q+D+C GD+G + Y G++SF K+ + Sbjct: 268 PVGVQPILNEHTFCAGLSKYQEDTCYGDAGSAFAVHDKDDDTWYAAGILSFDKS--CRTA 325 Query: 233 VPGVYTNLCKFTEWIEKTVQAS 254 GVY + +WI+ T+ + Sbjct: 326 EYGVYVRVTSILDWIQTTIADN 347 >1PQ7-A nrPDB Length = 224 Score = 210 bits (536), Expect = 3e-55, Method: Composition-based stats. Identities = 69/224 (30%), Positives = 99/224 (44%), Gaps = 9/224 (4%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 I+ G S P+ ++ +C G L++ VL+AAHC G + + + Sbjct: 1 IVGGTSASAGDFPFIVSISRNGGPWCGGSLLNANTVLTAAHCVSGYAQSGFQIRAGSLSR 60 Query: 91 EPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIAS--QCPTAGNSC 148 G S HP Y+ NDL ++KL S+ I +A+ P AG+S Sbjct: 61 TSGGITSSLSSVRVHPSYSGNN--NDLAILKLSTSIPSGGNIGYARLAASGSDPVAGSSA 118 Query: 149 LVSGWGLLANG--RMPTVLQCVNVSVVSEEVCSKLYD-PLYHPSMFCAGGGHDQKDSCNG 205 V+GWG + G P L V V +VS C Y MFCAG KDSC G Sbjct: 119 TVAGWGATSEGGSSTPVNLLKVTVPIVSRATCRAQYGTSAITNQMFCAGVSSGGKDSCQG 178 Query: 206 DSGGPLI-CNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIE 248 DSGGP++ + L G VS+G C + GVY ++ +I+ Sbjct: 179 DSGGPIVDSSNTLIGAVSWGNG-CARPNYSGVYASVGALRSFID 221 >1GPZ-A nrPDB Length = 399 Score = 210 bits (536), Expect = 4e-55, Method: Composition-based stats. Identities = 62/255 (24%), Positives = 107/255 (41%), Gaps = 33/255 (12%) Query: 24 VSGSCSQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCF---------Q 74 QII G+ + PWQ + G L+ +W+L+AAH Sbjct: 151 PVEQRQQIIGGQKAKMGNFPWQVFTNIHGRG--GGALLGDRWILTAAHTLYPKEHEAQSN 208 Query: 75 NSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLAN---DLMLIKLDESVSESDT 131 S + LG ++E + G+ HP+Y + N D+ L++L+ SV+ Sbjct: 209 ASLDVFLGHTNVEELMKLGNH--PIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPN 266 Query: 132 IRSISIASQC--PTAGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYDP----- 184 + I + G VSG+G++ ++ L+ V + V + + C Sbjct: 267 LLPICLPDNDTFYDLGLMGYVSGFGVMEE-KIAHDLRFVRLPVANPQACENWLRGKNRMD 325 Query: 185 LYHPSMFCAGGGHDQKDSCNGDSGG------PLICNGYLQGLVSFGKAPCGQVGVPGVYT 238 ++ +MFCAG ++D+C GDSGG P G+VS+G C + G YT Sbjct: 326 VFSQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGIG-CSRG--YGFYT 382 Query: 239 NLCKFTEWIEKTVQA 253 + + +WI+K ++ Sbjct: 383 KVLNYVDWIKKEMEE 397 >2QY0-B nrPDB Length = 242 Score = 209 bits (533), Expect = 9e-55, Method: Composition-based stats. Identities = 61/248 (24%), Positives = 106/248 (42%), Gaps = 33/248 (13%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCF---------QNSYTIGL 81 II G+ + PWQ + G L+ +W+L+AAH S + L Sbjct: 1 IIGGQKAKMGNFPWQVFTNIHGRG--GGALLGDRWILTAAHTLYPKEHEAQSNASLDVFL 58 Query: 82 GLHSLEADQEPGSQMVEASLSVRHPEYNRPLLAN---DLMLIKLDESVSESDTIRSISIA 138 G ++E + G+ HP+Y + N D+ L++L+ SV+ + I + Sbjct: 59 GHTNVEELMKLGNH--PIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPICLP 116 Query: 139 SQC--PTAGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYDP-----LYHPSMF 191 G VSG+G++ ++ L+ V + V + + C ++ +MF Sbjct: 117 DNDTFYDLGLMGYVSGFGVMEE-KIAHDLRFVRLPVANPQACENWLRGKNRMDVFSQNMF 175 Query: 192 CAGGGHDQKDSCNGDSGG------PLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTE 245 CAG ++D+C GDSGG P G+VS+G C + G YT + + + Sbjct: 176 CAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGIG-CSRG--YGFYTKVLNYVD 232 Query: 246 WIEKTVQA 253 WI+K ++ Sbjct: 233 WIKKEMEE 240 >1MD7-A nrPDB Length = 328 Score = 209 bits (532), Expect = 1e-54, Method: Composition-based stats. Identities = 60/254 (23%), Positives = 107/254 (42%), Gaps = 33/254 (12%) Query: 24 VSGSCSQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCF---------Q 74 +II G+ + PWQ + G L+ +W+L+AAH Sbjct: 83 PVEQRQRIIGGQKAKMGNFPWQVFTNIHGRG--GGALLGDRWILTAAHTLYPKEHEAQSN 140 Query: 75 NSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLAN---DLMLIKLDESVSESDT 131 S + LG ++E + G+ HP+Y + N D+ L++L+ SV+ Sbjct: 141 ASLDVFLGHTNVEELMKLGNH--PIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPN 198 Query: 132 IRSISIASQC--PTAGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYDP----- 184 + I + G VSG+G++ ++ L+ V + V + + C Sbjct: 199 LLPICLPDNDTFYDLGLMGYVSGFGVMEE-KIAHDLRFVRLPVANPQACENWLRGKNRMD 257 Query: 185 LYHPSMFCAGGGHDQKDSCNGDSGG------PLICNGYLQGLVSFGKAPCGQVGVPGVYT 238 ++ +MFCAG ++D+C GD+GG P G+VS+G C + G YT Sbjct: 258 VFSQNMFCAGHPSLKQDACQGDAGGVFAVRDPNTDRWVATGIVSWGIG-CSRG--YGFYT 314 Query: 239 NLCKFTEWIEKTVQ 252 + + +WI+K ++ Sbjct: 315 KVLNYVDWIKKEME 328 >1YM0-A nrPDB Length = 238 Score = 208 bits (530), Expect = 2e-54, Method: Composition-based stats. Identities = 66/240 (27%), Positives = 105/240 (43%), Gaps = 18/240 (7%) Query: 31 IINGEDCSPHSQPWQAALVMENE--LFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEA 88 I+ G + P+ PWQ ++ ++ FC G +++ +WV+ AAHC Q + L E Sbjct: 1 IVGGIEARPYEFPWQVSVRRKSSDSHFCGGSIINDRWVVCAAHCMQGEAPALVSLVVGEH 60 Query: 89 DQEPGS---QMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPT-A 144 D S Q + + Y+ L ND+ +IK +++ + I Sbjct: 61 DSSAASTVRQTHDVDSIFVNENYDPATLENDVSVIKTAVAITFDINVGPICAPDPANDYV 120 Query: 145 GNSCLVSGWGLLANGRM--PTVLQCVNVSVVSEEVCSKLY-DPLYHPSMFCAGGGHD--Q 199 SGWG + +G + P VL+ V +++ + C +Y + M CA Sbjct: 121 YRKSQCSGWGTINSGGVCCPAVLRYVTLNITTNAFCDAVYTSDTIYDDMICATDNTGMTD 180 Query: 200 KDSCNGDSGGPLICNG-----YLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 +DSC GDSGGPL L G+VS+G C G PGVY+ + WI T+ + Sbjct: 181 RDSCQGDSGGPLSVKDGSGIFSLVGIVSWGIG-CAS-GYPGVYSRVGFHAGWITDTITNN 238 >6BQM-A nrPDB Length = 506 Score = 207 bits (528), Expect = 3e-54, Method: Composition-based stats. Identities = 70/251 (27%), Positives = 107/251 (42%), Gaps = 33/251 (13%) Query: 25 SGSCSQIINGEDCSPHSQPWQAAL--VMENELFCSGVLVHPQWVLSAAHCFQ--NSYTIG 80 SG S+II GE + P+ AL + +FC G + ++VL+AAHC + Sbjct: 5 SGVSSRIIGGEQATAGEWPYMVALTARNSSHVFCGGSYLGGRYVLTAAHCVDKEDPAKGD 64 Query: 81 LGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLD------ESVSESDTIRS 134 + L + + + ++ + H Y + ND+ +++L+ SV SD+ Sbjct: 65 VLLGAFDMNDVNTAERIHVRQIYVHNSYITASMGNDIAVLELERDPLPRRSVQISDSSDF 124 Query: 135 ISIASQCPTA----GNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYD------- 183 + P GN V G T+L V V V C Sbjct: 125 NELTKDSPMTVIGFGNRKEVDG----EKSDPATILHQVQVPFVPLPECKTKGSDQDAKNN 180 Query: 184 -PLYHPSMFCAGGGHDQKDSCNGDSGGPLIC---NGYLQ-GLVSFGKAPCGQVGVPGVYT 238 + FCAG KD+C+GD+GGP+ NG Q G+VS+G CG+ PGVYT Sbjct: 181 YSQLTNNAFCAGSF--GKDACSGDAGGPIFFDSNNGRKQMGVVSWGDG-CGRANSPGVYT 237 Query: 239 NLCKFTEWIEK 249 NL F +W++ Sbjct: 238 NLSVFNDWLDD 248 >2HLC-A nrPDB Length = 230 Score = 206 bits (526), Expect = 6e-54, Method: Composition-based stats. Identities = 67/232 (28%), Positives = 108/232 (46%), Gaps = 17/232 (7%) Query: 31 IINGEDCSPHSQPWQA----ALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSL 86 IING + P+QA L + ++C G L+ +W+L+AAHC ++ ++ + L S Sbjct: 1 IINGYEAYTGLFPYQAGLDITLQDQRRVWCGGSLIDNKWILTAAHCVHDAVSVVVYLGS- 59 Query: 87 EADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGN 146 A Q G +V + + H +N ND+ LIK+ V +D I+ I + S Sbjct: 60 -AVQYEGEAVVNSERIISHSMFNPDTYLNDVALIKIPH-VEYTDNIQPIRLPSGEELNNK 117 Query: 147 S----CLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYDP-LYHPSMFCAGGGHDQKD 201 VSGWG + +LQ V+ + C++ Y P + S C G D K Sbjct: 118 FENIWATVSGWG--QSNTDTVILQYTYNLVIDNDRCAQEYPPGIIVESTIC-GDTSDGKS 174 Query: 202 SCNGDSGGPLICNG--YLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 251 C GDSGGP + + L G+VSF + G P ++ + + +WI++ Sbjct: 175 PCFGDSGGPFVLSDKNLLIGVVSFVSGAGCESGKPVGFSRVTSYMDWIQQNT 226 >2ASU-B nrPDB Length = 234 Score = 205 bits (523), Expect = 1e-53, Method: Composition-based stats. Identities = 64/236 (27%), Positives = 105/236 (44%), Gaps = 24/236 (10%) Query: 31 IINGEDCSPHSQPWQAALV-MENELFCSGVLVHPQWVLSAAHCFQN------SYTIGLGL 83 ++ G P + PW +L + + FC G LV QW+L+A CF + Y + LG Sbjct: 1 VVGGH---PGNSPWTVSLRNRQGQHFCGGSLVKEQWILTARQCFSSCHMPLTGYEVWLGT 57 Query: 84 HSLE-ADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCP 142 EP Q V + V P ++ L+L+KL+ SV+ + + I + + Sbjct: 58 LFQNPQHGEPSLQRVPVAKMVCGPSGSQ------LVLLKLERSVTLNQRVALICLPPEWY 111 Query: 143 --TAGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQK 200 G C ++GWG TVL ++V+S + C+ + S C G Sbjct: 112 VVPPGTKCEIAGWGETKGTGNDTVLNVALLNVISNQECNIKHRGRVRESEMCTEGLLAPV 171 Query: 201 DSCNGDSGGPLIC----NGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 252 +C GD GGPL C + L+G++ + C + P V+T + F +WI K ++ Sbjct: 172 GACEGDYGGPLACFTHNSWVLEGIIIPNR-VCARSRWPAVFTRVSVFVDWIHKVMR 226 >3I77-A nrPDB Length = 230 Score = 205 bits (522), Expect = 2e-53, Method: Composition-based stats. Identities = 66/237 (27%), Positives = 98/237 (41%), Gaps = 22/237 (9%) Query: 31 IINGEDCSPHSQPWQAALVME-NELFCSGVLVHPQWVLSAAHCF-----QNSYTIGLGLH 84 ++ G + P+ L+ E NE FC G L VL+AAHC S T G+ Sbjct: 1 VVGGTRAAQGEFPFMVRLINEENEGFCGGALYAQDIVLTAAHCVSGSGNNTSITATGGVV 60 Query: 85 SLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTA 144 L Q + V ++ ++ P + + D LIKL + +++ ++ IA+ Sbjct: 61 DL---QSSSAVKVRSTKVLQAPGFTKETYGKDWALIKLAQPINQP----TLKIATTTAYN 113 Query: 145 GNSCLVSGWG-LLANGRMPTVLQCVNVSVVSEEVCSKLYDPL-YHPSMFCAGGGH-DQKD 201 + V+GWG G L NV VS+ C + M CAG D Sbjct: 114 QGTFTVAGWGANREGGSQQRYLLKANVPFVSDAACRSSSSFILVANEMICAGYPDTGGVD 173 Query: 202 SCNGDSGGPLI-----CNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQA 253 +C GDSGGP+ G+VS+G C + G PGVYT + F I + Sbjct: 174 TCQGDSGGPMFRKDNADEWIQVGIVSWGYG-CARPGYPGVYTEVSTFASAIASAART 229 >2PKA-B nrPDB Length = 152 Score = 202 bits (515), Expect = 1e-52, Method: Composition-based stats. Identities = 53/150 (35%), Positives = 83/150 (55%), Gaps = 4/150 (2%) Query: 109 NRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLVSGWGLLANG----RMPTV 164 + ++DLML++L +D ++ + + +Q P G++C SGWG + G P Sbjct: 2 DGKDYSHDLMLLRLQSPAKITDAVKVLELPTQEPELGSTCEASGWGSIEPGPDDFEFPDE 61 Query: 165 LQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDSGGPLICNGYLQGLVSFG 224 +QCV ++++ C+ + SM CAG KD+C GDSGGPLICNG QG+ S+G Sbjct: 62 IQCVQLTLLQNTFCADAHPDKVTESMLCAGYLPGGKDTCMGDSGGPLICNGMWQGITSWG 121 Query: 225 KAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 PCG P +YT L + +WI+ T+ + Sbjct: 122 HTPCGSANKPSIYTKLIFYLDWIDDTITEN 151 >1SI5-H nrPDB Length = 240 Score = 201 bits (513), Expect = 2e-52, Method: Composition-based stats. Identities = 62/236 (26%), Positives = 100/236 (42%), Gaps = 25/236 (10%) Query: 31 IING--EDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQN----SYTIGLGLH 84 ++NG + W +L N+ C G L+ WVL+A CF + Y LG+H Sbjct: 1 VVNGIPTRTNIG---WMVSLRYRNKHICGGSLIKESWVLTARQCFPSRDLKDYEAWLGIH 57 Query: 85 SLEAD-QEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPT 143 + E Q++ S V PE +DL+L+KL D + +I + + T Sbjct: 58 DVHGRGDEKCKQVLNVSQLVYGPE------GSDLVLMKLARPAVLDDFVSTIDLPNYGST 111 Query: 144 AG--NSCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYH--PSMFCAGGGHDQ 199 SC V GWG +L+ ++ ++ E CS+ + S CAG Sbjct: 112 IPEKTSCSVYGWGYTGLINYDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAGAEKIG 171 Query: 200 KDSCNGDSGGPLICNGYLQ----GLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 251 C GD GGPL+C + G++ G+ C PG++ + + +WI K + Sbjct: 172 SGPCEGDYGGPLVCEQHKMRMVLGVIVPGRG-CAIPNRPGIFVRVAYYAKWIHKII 226 >3BEU-A nrPDB Length = 224 Score = 201 bits (512), Expect = 2e-52, Method: Composition-based stats. Identities = 63/235 (26%), Positives = 96/235 (40%), Gaps = 24/235 (10%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCF-----QNSYTIGLGLHS 85 ++ G + P+ L M C G L VL+AAHC S T G+ Sbjct: 1 VVGGTRAAQGEFPFMVRLSMG----CGGALYAQDIVLTAAHCVSGSGNNTSITATGGVVD 56 Query: 86 LEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAG 145 L Q + V ++ ++ P + + D LIKL + +++ ++ IA+ Sbjct: 57 L---QSSSAVKVRSTKVLQAPGFTKETYGKDWALIKLAQPINQP----TLKIATTTAYNQ 109 Query: 146 NSCLVSGWG-LLANGRMPTVLQCVNVSVVSEEVCSKLYDPL-YHPSMFCAGGGHDQKDSC 203 + V+GWG G L NV VS+ C + M CAG Q+D+C Sbjct: 110 GTFTVAGWGANREGGSQQRYLLKANVPFVSDAACRSSSSFILVANEMICAGYDTKQEDTC 169 Query: 204 NGDSGGPLI-----CNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQA 253 GDSGGP+ G+VS+G+ C + G GVYT + F I + Sbjct: 170 QGDSGGPMFRKDNADEWVQVGIVSWGEG-CARKGKYGVYTEVSTFASAIASAART 223 >2FMJ-A nrPDB Length = 222 Score = 195 bits (496), Expect = 2e-50, Method: Composition-based stats. Identities = 65/235 (27%), Positives = 95/235 (40%), Gaps = 26/235 (11%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCF-----QNSYTIGLGLHS 85 ++ G + P+ L M C G L VL+AAHC S T G+ Sbjct: 1 VVGGTRAAQGEFPFMVRLSMG----CGGALYAQDIVLTAAHCVSGSGNNTSITATGGVVD 56 Query: 86 LEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAG 145 L Q + V ++ ++ P YN D LIKL + +++ ++ IA+ Sbjct: 57 L---QSSSAVKVRSTKVLQAPGYN--GTGKDWALIKLAQPINQP----TLKIATTTAYNQ 107 Query: 146 NSCLVSGWG-LLANGRMPTVLQCVNVSVVSEEVCSKLY-DPLYHPSMFCAGGGHDQKDSC 203 + V+GWG G L NV VS+ C Y + L CAG D+C Sbjct: 108 GTFTVAGWGANREGGSQQRYLLKANVPFVSDAACRSAYGNELVANEEICAGYDTGGVDTC 167 Query: 204 NGDSGGPLI-----CNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQA 253 GDSGGP+ G+VS+G+ C + G GVYT + F I + Sbjct: 168 QGDSGGPMFRKDNADEWIQVGIVSWGEG-CARKGKYGVYTEVSTFASAIASAART 221 >5XW8-A nrPDB Length = 133 Score = 186 bits (473), Expect = 8e-48, Method: Composition-based stats. Identities = 46/135 (34%), Positives = 75/135 (55%), Gaps = 2/135 (1%) Query: 23 LVSGSCSQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLG 82 + +I+ G C+ +S P+Q +L FC G L++ QWV+SAAHC+++ + LG Sbjct: 1 FPTDDDDKIVGGYTCAANSIPYQVSL-NSGSHFCGGSLINSQWVVSAAHCYKSRIQVRLG 59 Query: 83 LHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCP 142 H+++ E Q + A+ + HP +N L ND+MLIKL + + + ++S+ C Sbjct: 60 EHNIDVL-EGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRSCA 118 Query: 143 TAGNSCLVSGWGLLA 157 AG CL+SGWG Sbjct: 119 AAGTECLISGWGNTK 133 >3H7T-A nrPDB Length = 235 Score = 175 bits (444), Expect = 2e-44, Method: Composition-based stats. Identities = 55/234 (23%), Positives = 99/234 (42%), Gaps = 13/234 (5%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 II G+ +PW ++++ + FC G ++ +V++AA C + + +H + + Sbjct: 1 IIGGKKSDITKEPWAVGVLVDEKPFCGGSILTANFVITAAQCVDGTKPSDISIHYGSSYR 60 Query: 91 EPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESD-TIRSISIAS--QCPTAGNS 147 V A Y+ + N+ +I+ + + D T + I + S P S Sbjct: 61 TTKGTSVMAKKIYI-VRYHPLTMQNNYAVIETEMPIKLDDKTTKKIELPSLLYDPEPDTS 119 Query: 148 CLVSGWGLL--ANGRMPTVLQCVNVSVVSEEVCSKLY-----DPLYHPSMFCAGGGHDQK 200 LVSGWG + L N +VV + C + Y D + +FCAGG +D+ Sbjct: 120 VLVSGWGSTNFKSLEYSGDLMEANFTVVDRKSCEEQYKQIEADKYIYDGVFCAGGEYDET 179 Query: 201 DSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 GD+G P + NG L G+ S+ + P V+ + + I+ + Sbjct: 180 YIGYGDAGDPAVQNGTLVGVASYISSM--PSEFPSVFLRVGYYVLDIKDIISGK 231 >1M9U-A nrPDB Length = 241 Score = 175 bits (444), Expect = 2e-44, Method: Composition-based stats. Identities = 60/240 (25%), Positives = 98/240 (40%), Gaps = 26/240 (10%) Query: 31 IINGEDCSPHSQPWQAALVMENE---LFCSGVLVHPQWVLSAAHCFQ----NSYTIGLGL 83 +I G + SP PWQ + ++ C L+ LSA+HC N+ + GL Sbjct: 1 VIGGTNASPGEFPWQLSQQRQSGSWSHSCGASLLSSTSALSASHCVDGVLPNNIRVIAGL 60 Query: 84 HSLEADQEPGSQMVEASLSVRHPEYNRPL--LANDLMLIKLDESVSESDTIRSISIASQC 141 + G+Q H Y +ND+ ++ L S+S I++ + + Sbjct: 61 W--QQSDTSGTQTANVDSYTMHENYGAGTASYSNDIAILHLATSISLGGNIQAAVLPANN 118 Query: 142 P--TAGNSCLVSGWGLLAN-GRMPTVLQCVNVSVVSEEVCSKLYDPL----YHPSMFCAG 194 AG +C++SGWG +P +LQ ++ V++ C+ + + C Sbjct: 119 NNDYAGTTCVISGWGRTDGTNNLPDILQKSSIPVITTAQCTAAMVGVGGANIWDNHICVQ 178 Query: 195 GGHDQKDSCNGDSGGPLICNG---YLQGLVSF----GKAPCGQVGVPGVYTNLCKFTEWI 247 +CNGDSGGPL C + G+ S+ G C P VYT + + WI Sbjct: 179 DPAGNTGACNGDSGGPLNCPDGGTRVVGVTSWVVSSGLGAC-LPDYPSVYTRVSAYLGWI 237 >3H7O-A nrPDB Length = 228 Score = 173 bits (439), Expect = 6e-44, Method: Composition-based stats. Identities = 55/232 (23%), Positives = 93/232 (40%), Gaps = 15/232 (6%) Query: 33 NGEDCSPHSQPWQAALVM---ENELFCSGVLVHPQWVLSAAHCF--QNSYTIGLGLHSLE 87 GE PW A+ E L C G ++ +VL+AAHC Q TI + S Sbjct: 2 GGEKTDIKQVPWTVAVRTYPGEESLTCGGAILSQWFVLTAAHCVFDQKPETIVIQYESTN 61 Query: 88 ADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSE-SDTIRSISIASQC--PTA 144 ++PG S Y + + ND+ +++L + + + P Sbjct: 62 LWEDPGKSDPYVSHVYL-SFYRQETMENDIAILELSRPLKLDGLKSKPAKLPDIEFRPKT 120 Query: 145 GNSCLVSGWGL-LANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHP-SMFCAGGGHDQKDS 202 G+ LVSG+G L+ ++VV + C Y P++ +FCA Sbjct: 121 GSDVLVSGYGDGQTMDPKDHDLKSAQLTVVDLDECRTKYGPIFLSLQVFCA--QKVGVSL 178 Query: 203 CNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 +GD+G P + L G+ ++ P G P V+T + + WI+ ++ Sbjct: 179 ESGDAGDPTVQQDTLVGVAAY--FPKRPEGAPEVFTKVGSYVSWIQDIIKKK 228 >3VGC-B nrPDB Length = 131 Score = 155 bits (393), Expect = 1e-38, Method: Composition-based stats. Identities = 39/130 (30%), Positives = 68/130 (52%), Gaps = 3/130 (2%) Query: 31 IINGEDCSPHSQPWQAALVME-NELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEAD 89 I+NGE+ P S PWQ +L + FC G L++ WV++AAHC + + + + Sbjct: 1 IVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGVTTSDVVVAGEFDQGS 60 Query: 90 QEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIA--SQCPTAGNS 147 Q ++ + ++ +YN + ND+ L+KL + S S T+ ++ + S AG + Sbjct: 61 SSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDDFAAGTT 120 Query: 148 CLVSGWGLLA 157 C+ +GWGL Sbjct: 121 CVTTGWGLTR 130 >1AKS-B nrPDB Length = 98 Score = 154 bits (391), Expect = 3e-38, Method: Composition-based stats. Identities = 42/98 (42%), Positives = 58/98 (59%), Gaps = 1/98 (1%) Query: 157 ANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDSGGPLICNGY 216 + P++LQC+ V+S C Y +M C G KDSC GDSGGP++CNG Sbjct: 2 SGSSYPSLLQCLKAPVLSNSSCKSSYPGQITGNMICVGFLQGGKDSCQGDSGGPVVCNGQ 61 Query: 217 LQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 LQG+VS+G C Q PGVYT +C + WI++T+ A+ Sbjct: 62 LQGIVSWGYG-CAQKNKPGVYTKVCNYVNWIQQTIAAN 98 >2JET-B nrPDB Length = 128 Score = 153 bits (388), Expect = 6e-38, Method: Composition-based stats. Identities = 35/127 (27%), Positives = 62/127 (48%), Gaps = 3/127 (2%) Query: 34 GEDCSPHSQPWQAALVME-NELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQEP 92 GED P S PWQ +L + FC G L+ WV++AAHC + + + + E Sbjct: 1 GEDAIPGSWPWQVSLQDKTGFHFCGGSLISEDWVVTAAHCGVKTSDVVVAGEFDQGSDEE 60 Query: 93 GSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIAS--QCPTAGNSCLV 150 Q+++ + ++P++N + ND+ L+KL S+T+ ++ + + G C Sbjct: 61 NIQVLKIAQVFKNPKFNMFTVRNDITLLKLATPAQFSETVSAVCLPNVDDDFPPGTVCAT 120 Query: 151 SGWGLLA 157 +GWG Sbjct: 121 TGWGKTK 127 >1RIW-B nrPDB Length = 147 Score = 151 bits (382), Expect = 3e-37, Method: Composition-based stats. Identities = 43/147 (29%), Positives = 63/147 (42%), Gaps = 18/147 (12%) Query: 31 IINGEDCSPHSQPWQAALVMEN--ELFCSGVLVHPQWVLSAAHCF----------QNSYT 78 I+ G D PWQ L ++ EL C L+ +WVL+AAHC +N Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 79 IGLGLHSLEADQEPGSQMVEASLSVRHPEYN-RPLLANDLMLIKLDESVSESDTIRSISI 137 + +G HS + ++ HP YN R L D+ L+KL + V+ SD I + + Sbjct: 61 VRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCL 120 Query: 138 ASQCP-----TAGNSCLVSGWGLLANG 159 + AG V+GWG L Sbjct: 121 PDRETAASLLQAGYKGRVTGWGNLKET 147 >2I6S-A nrPDB Length = 517 Score = 147 bits (372), Expect = 4e-36, Method: Composition-based stats. Identities = 56/290 (19%), Positives = 101/290 (34%), Gaps = 63/290 (21%) Query: 24 VSGSCSQI--INGEDCSPHSQ---PWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYT 78 VS I + + Q PW + +++ C G L+ QWVL+AAHCF++ Sbjct: 220 VSKLTDTICGVGNMSANASDQERTPWHVTIKPKSQETCRGALISDQWVLTAAHCFRDGND 279 Query: 79 IGLGLHSLEADQEPGSQMVEASLSVRHPEYNR---------PLLANDLMLIKLDESVSES 129 L ++ + + +V P ++ +D+ L+KL + V S Sbjct: 280 HSLWRVNVGDPKSQWGKEFLIEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMS 339 Query: 130 DTIRSISIA-------SQCPTAGNSCLVSGWGLLANGRMPTVLQ-----CVNVSV---VS 174 R I + + G++C LL +P +N+++ V Sbjct: 340 THARPICLPCTMEANLALRRPQGSTCRDHENELLNKQSVPAHFVALNGSKLNINLKMGVE 399 Query: 175 EEVCSKL-------------YDPLYHPSMFCAGGGHDQKDSCNGDSGGPLICNGYL---- 217 C+++ + C+G D + C G+SGG + Sbjct: 400 WTSCAEVVSQEKTMFPNLTDVREVVTDQFLCSGTQED-ESPCKGESGGAVFLERRFRFFQ 458 Query: 218 QGLVSFG-KAPC-------GQVGVP--------GVYTNLCKFTEWIEKTV 251 GLVS+G PC + P + NL + W+ + + Sbjct: 459 VGLVSWGLYNPCLGSADKNSRKRAPRSKVPPPRDFHINLFRMQPWLRQHL 508 >1BBR-H nrPDB Length = 150 Score = 146 bits (370), Expect = 6e-36, Method: Composition-based stats. Identities = 39/147 (26%), Positives = 61/147 (41%), Gaps = 18/147 (12%) Query: 31 IINGEDCSPHSQPWQAALVMEN--ELFCSGVLVHPQWVLSAAHCF----------QNSYT 78 I+ G+D PWQ L ++ EL C L+ +WVL+AAHC + Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDLL 60 Query: 79 IGLGLHSLEADQEPGSQMVEASLSVRHPEYN-RPLLANDLMLIKLDESVSESDTIRSISI 137 + +G HS + ++ HP YN + L D+ L+KL + SD I + + Sbjct: 61 VRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVCL 120 Query: 138 A-----SQCPTAGNSCLVSGWGLLANG 159 ++ AG V+GWG Sbjct: 121 PDKQTAAKLLHAGFKGRVTGWGNRRET 147 >2WIN-I nrPDB Length = 507 Score = 145 bits (367), Expect = 1e-35, Method: Composition-based stats. Identities = 68/278 (24%), Positives = 100/278 (35%), Gaps = 76/278 (27%) Query: 40 HSQPWQAALV----MENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQEPGSQ 95 H QPWQA + + C G +V +VL+AAHCF T+ HS++ + Sbjct: 232 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCF----TVDDKEHSIKVSVGGEKR 287 Query: 96 MVEASLSVRHPEYN---------RPLLANDLMLIKLDESVSESDTIRSISIA-------S 139 +E + + HP YN D+ LIKL + TIR I + + Sbjct: 288 DLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTTRA 347 Query: 140 QCPTAGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEV------------------CSK- 180 +C +P Q + VSEE C + Sbjct: 348 LRLPPTTTCQ-----QQKEELLPA--QDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERD 400 Query: 181 -LYDP----------LYHPSMFCAGGGHDQKD--SCNGDSGGPLICNGY----LQGLVSF 223 Y P + P C GG D +C GDSGGPLI + G++S+ Sbjct: 401 AQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISW 460 Query: 224 G-----KAPCGQVGVP----GVYTNLCKFTEWIEKTVQ 252 G K Q VP + NL + W+++ +Q Sbjct: 461 GVVDVCKNQKRQKQVPAHARDFHINLFQVLPWLKEKLQ 498 >1DLE-A nrPDB Length = 298 Score = 144 bits (365), Expect = 3e-35, Method: Composition-based stats. Identities = 68/278 (24%), Positives = 100/278 (35%), Gaps = 76/278 (27%) Query: 40 HSQPWQAALV----MENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQEPGSQ 95 H QPWQA + + C G +V +VL+AAHCF T+ HS++ + Sbjct: 25 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCF----TVDDKEHSIKVSVGGEKR 80 Query: 96 MVEASLSVRHPEYN---------RPLLANDLMLIKLDESVSESDTIRSISIA-------S 139 +E + + HP YN D+ LIKL + TIR I + + Sbjct: 81 DLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTTRA 140 Query: 140 QCPTAGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEV------------------CSK- 180 +C +P Q + VSEE C + Sbjct: 141 LRLPPTTTCQ-----QQKEELLPA--QDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERD 193 Query: 181 -LYDP----------LYHPSMFCAGGGHDQKD--SCNGDSGGPLICNGY----LQGLVSF 223 Y P + P C GG D +C GDSGGPLI + G++S+ Sbjct: 194 AQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISW 253 Query: 224 G-----KAPCGQVGVP----GVYTNLCKFTEWIEKTVQ 252 G K Q VP + NL + W+++ +Q Sbjct: 254 GVVDVCKNQKRQKQVPAHARDFHINLFQVLPWLKEKLQ 291 >2OK5-A nrPDB Length = 752 Score = 142 bits (358), Expect = 2e-34, Method: Composition-based stats. Identities = 68/278 (24%), Positives = 100/278 (35%), Gaps = 76/278 (27%) Query: 40 HSQPWQAALV----MENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQEPGSQ 95 H QPWQA + + C G +V +VL+AAHCF T+ HS++ + Sbjct: 476 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCF----TVDDKEHSIKVSVGGEKR 531 Query: 96 MVEASLSVRHPEYN---------RPLLANDLMLIKLDESVSESDTIRSISIA-------S 139 +E + + HP YN D+ LIKL + TIR I + + Sbjct: 532 DLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTTRA 591 Query: 140 QCPTAGNSCLVSGWGLLANGRMPTVLQCVNVSVVSEEV------------------CSK- 180 +C +P Q + VSEE C + Sbjct: 592 LRLPPTTTCQ-----QQKEELLPA--QDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERD 644 Query: 181 -LYDP----------LYHPSMFCAGGGHDQKD--SCNGDSGGPLICNGY----LQGLVSF 223 Y P + P C GG D +C GDSGGPLI + G++S+ Sbjct: 645 AQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISW 704 Query: 224 G-----KAPCGQVGVP----GVYTNLCKFTEWIEKTVQ 252 G K Q VP + NL + W+++ +Q Sbjct: 705 GVVDVCKNQKRQKQVPAHARDFHINLFQVLPWLKEKLQ 742 >1BBR-E nrPDB Length = 109 Score = 121 bits (303), Expect = 4e-28, Method: Composition-based stats. Identities = 35/100 (35%), Positives = 52/100 (52%), Gaps = 10/100 (10%) Query: 161 MPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHD---QKDSCNGDSGGPLICN--- 214 P+VLQ VN+ +V VC +MFCAG + D+C GDSGGP + Sbjct: 6 QPSVLQVVNLPLVERPVCKASTRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPY 65 Query: 215 ---GYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 251 Y G+VS+G+ C + G G YT++ + +WI+K + Sbjct: 66 NNRWYQMGIVSWGEG-CDRDGKYGFYTHVFRLKKWIQKVI 104 >2HNT-F nrPDB Length = 105 Score = 120 bits (302), Expect = 6e-28, Method: Composition-based stats. Identities = 35/100 (35%), Positives = 52/100 (52%), Gaps = 10/100 (10%) Query: 161 MPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGG---GHDQKDSCNGDSGGPLICN--- 214 P+VLQ VN+ +V VC +MFCAG + D+C GDSGGP + Sbjct: 2 QPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPF 61 Query: 215 ---GYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 251 Y G+VS+G+ C + G G YT++ + +WI+K + Sbjct: 62 NNRWYQMGIVSWGEG-CDRDGKYGFYTHVFRLKKWIQKVI 100 >2JET-C nrPDB Length = 99 Score = 116 bits (291), Expect = 9e-27, Method: Composition-based stats. Identities = 35/99 (35%), Positives = 50/99 (50%), Gaps = 7/99 (7%) Query: 160 RMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDSGGPLICN----G 215 + P LQ + +VSE C K + M CAG DSC GDSGGPL+C Sbjct: 4 KTPEKLQQAALPIVSEADCKKSWGSKITDVMTCAGAS--GVDSCMGDSGGPLVCQKDGVW 61 Query: 216 YLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 L G+VS+G C PGVY+ + W+++ ++A+ Sbjct: 62 TLAGIVSWGSGVCSTS-TPGVYSRVTALMPWVQQILEAN 99 >3RU4-E nrPDB Length = 96 Score = 116 bits (290), Expect = 1e-26, Method: Composition-based stats. Identities = 33/99 (33%), Positives = 49/99 (49%), Gaps = 7/99 (7%) Query: 160 RMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDSGGPLICN----G 215 P LQ ++ ++S C K + +M CAG SC GDSGGPL+C Sbjct: 1 NTPDRLQQASLPLLSNTNCKKYWGTKIKDAMICAGAS--GVSSCMGDSGGPLVCKKNGAW 58 Query: 216 YLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254 L G+VS+G + C PGVY + W+++T+ A+ Sbjct: 59 TLVGIVSWGSSTCSTS-TPGVYARVTALVNWVQQTLAAN 96 >2KAI-A nrPDB Length = 80 Score = 114 bits (286), Expect = 4e-26, Method: Composition-based stats. Identities = 32/79 (40%), Positives = 47/79 (59%), Gaps = 1/79 (1%) Query: 31 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 90 II G +C +S PWQ A+ + C GVLV+P+WVL+AAHC ++Y + LG H+L + Sbjct: 1 IIGGRECEKNSHPWQVAIYHYSSFQCGGVLVNPKWVLTAAHCKNDNYEVWLGRHNL-FEN 59 Query: 91 EPGSQMVEASLSVRHPEYN 109 E +Q + HP +N Sbjct: 60 ENTAQFFGVTADFPHPGFN 78 >3F1S-B nrPDB Length = 283 Score = 108 bits (270), Expect = 2e-24, Method: Composition-based stats. Identities = 44/228 (19%), Positives = 83/228 (36%), Gaps = 32/228 (14%) Query: 43 PWQAALVM-ENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQEPGSQMVEASL 101 PWQ L E + FC GV++ +VL+ A C I + + Q+P M++ + Sbjct: 65 PWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYFNRTSQDP--LMIKITH 122 Query: 102 SVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPT-----AGNSCLVSGWGLL 156 H Y+ NDL L++L+ + + + L+SGW Sbjct: 123 VHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSGW-AR 181 Query: 157 ANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFC------AGGGHDQKDSCNGDSGGP 210 + L V++V E C ++ + +C A D Sbjct: 182 NGTDLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCERSSVAAMHWMDGS---------- 231 Query: 211 LICN-----GYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQA 253 ++ +L G++ G P G + T + +++ W ++ + A Sbjct: 232 VVTREHRGSWFLTGVL--GSQPVGGQAHMVLVTKVSRYSLWFKQIMNA 277 >1EPT-B nrPDB Length = 82 Score = 106 bits (265), Expect = 9e-24, Method: Composition-based stats. Identities = 27/83 (32%), Positives = 44/83 (53%), Gaps = 1/83 (1%) Query: 75 NSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRS 134 + + LG H+++ E Q + A+ + HP +N L ND+MLIKL + + + + Sbjct: 1 SRIQVRLGEHNIDVL-EGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVAT 59 Query: 135 ISIASQCPTAGNSCLVSGWGLLA 157 +S+ C AG CL+SGWG Sbjct: 60 VSLPRSCAAAGTECLISGWGNTK 82 >3H5C-B nrPDB Length = 317 Score = 105 bits (262), Expect = 2e-23, Method: Composition-based stats. Identities = 43/226 (19%), Positives = 82/226 (36%), Gaps = 32/226 (14%) Query: 43 PWQAALVM-ENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQEPGSQMVEASL 101 PWQ L E + FC GV++ +VL+ A C I + + Q+P M++ + Sbjct: 106 PWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYFNRTSQDP--LMIKITH 163 Query: 102 SVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPT-----AGNSCLVSGWGLL 156 H Y+ NDL L++L+ + + + L+SGW Sbjct: 164 VHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSGW-AR 222 Query: 157 ANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFC------AGGGHDQKDSCNGDSGGP 210 + L V++V E C ++ + +C A D Sbjct: 223 NGTDLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCERSSVAAMHWMDGS---------- 272 Query: 211 LICN-----GYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 251 ++ +L G++ G P G + T + +++ W ++ + Sbjct: 273 VVTREHRGSWFLTGVL--GSQPVGGQAHMVLVTKVSRYSLWFKQIM 316 >2HNT-E nrPDB Length = 81 Score = 77.5 bits (190), Expect = 5e-15, Method: Composition-based stats. Identities = 22/77 (28%), Positives = 32/77 (41%), Gaps = 6/77 (7%) Query: 94 SQMVEASLSVRHPEYN-RPLLANDLMLIKLDESVSESDTIRSISIASQCP-----TAGNS 147 ++ HP YN R L D+ L+KL + V+ SD I + + + AG Sbjct: 3 EKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYK 62 Query: 148 CLVSGWGLLANGRMPTV 164 V+GWG L V Sbjct: 63 GRVTGWGNLKETWTANV 79 >2HNT-C nrPDB Length = 70 Score = 76.4 bits (187), Expect = 1e-14, Method: Composition-based stats. Identities = 22/70 (31%), Positives = 31/70 (44%), Gaps = 12/70 (17%) Query: 31 IINGEDCSPHSQPWQAALVMEN--ELFCSGVLVHPQWVLSAAHCF----------QNSYT 78 I+ G D PWQ L ++ EL C L+ +WVL+AAHC +N Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 79 IGLGLHSLEA 88 + +G HS Sbjct: 61 VRIGKHSRTR 70 >1P3E-A nrPDB Length = 215 Score = 43.6 bits (102), Expect = 8e-05, Method: Composition-based stats. Identities = 35/180 (19%), Positives = 61/180 (33%), Gaps = 23/180 (12%) Query: 47 ALVMENELFCSGVLVHPQWVLSAAHCFQN----SYTIGLGLHSLEADQEPGSQMVEASLS 102 A + C+G L+ P +L+ HC N SY+ ++ D + + Sbjct: 23 AYITFGGSSCTGTLIAPNKILTNGHCVYNTASRSYSAKGSVYPGMNDSTAVNGSANMTEF 82 Query: 103 VRHPEY-NRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLVSGWGLLANGRM 161 Y N D +IK D + +T+ SI G + +SG+ Sbjct: 83 YVPSGYINTGASQYDFAVIKTDT--NIGNTVGYRSIRQVTNLTGTTIKISGYPGDKMRST 140 Query: 162 PTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDSGGPLI-CNGYLQGL 220 V Q V+ E + Y D+ +G+SG ++ N + G+ Sbjct: 141 GKVSQWEMSGSVTREDTNLAY---------------YTIDTFSGNSGSAMLDQNQQIVGV 185 >3LT3-A nrPDB Length = 217 Score = 37.5 bits (86), Expect = 0.006, Method: Composition-based stats. Identities = 32/174 (18%), Positives = 59/174 (33%), Gaps = 47/174 (27%) Query: 58 GVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDL 117 G ++ P V++ AH S + + G + EA++ Y+ + D+ Sbjct: 42 GFVISPDRVMTNAHVVAGSNNVTVYA---------GDKPFEATVV----SYDPSV---DV 85 Query: 118 MLIKLDESVSESDTIRSISIASQCPTAGNSCLVSGW-GLLANGRMPTVLQCVNVSVVSEE 176 ++ + A++ G +V G+ G P ++ Sbjct: 86 AIL-----AVPHLPPPPLVFAAEPAKTGADVVVLGYPGGGNFTATPARIREA-------- 132 Query: 177 VCSKLYDPLYHPSMFCAGGGH--------DQKDSCNGDSGGPLI-CNGYLQGLV 221 +L P + G + D GD+GGPLI NG + G+V Sbjct: 133 --IRLSGPDIY------GDPEPVTRDVYTIRADVEQGDAGGPLIDLNGQVLGVV 178 >2EA3-A nrPDB Length = 189 Score = 37.5 bits (86), Expect = 0.006, Method: Composition-based stats. Identities = 12/29 (41%), Positives = 14/29 (48%) Query: 205 GDSGGPLICNGYLQGLVSFGKAPCGQVGV 233 GDSGG L+ QG+ S G C G Sbjct: 135 GDSGGSLLAGNQAQGVTSGGSGNCRTGGT 163 >2PFE-A nrPDB Length = 186 Score = 37.1 bits (85), Expect = 0.007, Method: Composition-based stats. Identities = 12/28 (42%), Positives = 14/28 (50%) Query: 205 GDSGGPLICNGYLQGLVSFGKAPCGQVG 232 GDSGGP + QG+ S G C G Sbjct: 138 GDSGGPWLTGSQAQGVTSGGTGDCRSGG 165 >2OUA-A nrPDB Length = 188 Score = 36.3 bits (83), Expect = 0.014, Method: Composition-based stats. Identities = 14/43 (32%), Positives = 16/43 (37%), Gaps = 2/43 (4%) Query: 205 GDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFT-EW 246 GDSGG I QG+ S G C G Y + W Sbjct: 141 GDSGGSFISGTQAQGVTSGGSGNCRTGGT-TFYQEVNPMLNSW 182 >2SFA-A nrPDB Length = 191 Score = 35.9 bits (82), Expect = 0.017, Method: Composition-based stats. Identities = 12/29 (41%), Positives = 12/29 (41%) Query: 205 GDSGGPLICNGYLQGLVSFGKAPCGQVGV 233 GDSGG L GL S G C G Sbjct: 145 GDSGGALFAGSTALGLTSGGSGNCRTGGT 173 >5ILB-A nrPDB Length = 474 Score = 34.4 bits (78), Expect = 0.046, Method: Composition-based stats. Identities = 19/124 (15%), Positives = 41/124 (33%), Gaps = 28/124 (22%) Query: 35 EDCSPHSQPWQAALVMENELFCSGV--LVHPQWVLSAAHCFQNSYTIGLGLHSLEADQEP 92 +S PWQ + + +G ++ +L+ AHC ++ + + Sbjct: 17 HTAPDYSLPWQ----KQRQFTSTGSAFMIGDGKLLTNAHCVEHDTQVKVKRR-------- 64 Query: 93 GSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIR---SISIASQCPTAGNSCL 149 G + + + D+ L+ SV D + + + P +S Sbjct: 65 GDDRKYVAKVLV------RGVDCDIALL----SVESEDFWKGAEPLRL-GHLPRLQDSVT 113 Query: 150 VSGW 153 V G+ Sbjct: 114 VVGY 117 >4FLN-A nrPDB Length = 539 Score = 34.4 bits (78), Expect = 0.046, Method: Composition-based stats. Identities = 19/124 (15%), Positives = 41/124 (33%), Gaps = 28/124 (22%) Query: 35 EDCSPHSQPWQAALVMENELFCSGV--LVHPQWVLSAAHCFQNSYTIGLGLHSLEADQEP 92 +S PWQ + + +G ++ +L+ AHC ++ + + Sbjct: 57 HTAPDYSLPWQ----KQRQFTSTGSAFMIGDGKLLTNAHCVEHDTQVKVKRR-------- 104 Query: 93 GSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIR---SISIASQCPTAGNSCL 149 G + + + D+ L+ SV D + + + P +S Sbjct: 105 GDDRKYVAKVLV------RGVDCDIALL----SVESEDFWKGAEPLRL-GHLPRLQDSVT 153 Query: 150 VSGW 153 V G+ Sbjct: 154 VVGY 157 >2SGA-A nrPDB Length = 181 Score = 34.0 bits (77), Expect = 0.063, Method: Composition-based stats. Identities = 12/29 (41%), Positives = 12/29 (41%) Query: 205 GDSGGPLICNGYLQGLVSFGKAPCGQVGV 233 GDSGG L GL S G C G Sbjct: 135 GDSGGSLFAGSTALGLTSGGSGNCRTGGT 163 >5JYK-A nrPDB Length = 566 Score = 32.8 bits (74), Expect = 0.16, Method: Composition-based stats. Identities = 16/113 (14%), Positives = 36/113 (31%), Gaps = 18/113 (15%) Query: 41 SQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQEPGSQMVEAS 100 S PWQ + SG ++ + VL+ AH ++ + L + + Sbjct: 115 SLPWQRKRQYSSGS--SGFIIGGRRVLTNAHSVEHHTQVKLKKRGSDTKYLATVLAIGTE 172 Query: 101 LSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLVSGW 153 D+ L+ + + + + + P ++ V G+ Sbjct: 173 C--------------DIALLTVTDD-EFWEGVSPVEF-GDLPALQDAVTVVGY 209 >5ILA-A nrPDB Length = 301 Score = 32.1 bits (72), Expect = 0.26, Method: Composition-based stats. Identities = 16/113 (14%), Positives = 36/113 (31%), Gaps = 18/113 (15%) Query: 41 SQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQEPGSQMVEAS 100 S PWQ + SG ++ + VL+ AH ++ + L + + Sbjct: 115 SLPWQRKRQYSSGS--SGFIIGGRRVLTNAHSVEHHTQVKLKKRGSDTKYLATVLAIGTE 172 Query: 101 LSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLVSGW 153 D+ L+ + + + + + P ++ V G+ Sbjct: 173 C--------------DIALLTVTDD-EFWEGVSPVEF-GDLPALQDAVTVVGY 209 >1DUE-A nrPDB Length = 242 Score = 30.5 bits (68), Expect = 0.71, Method: Composition-based stats. Identities = 19/103 (18%), Positives = 33/103 (32%), Gaps = 14/103 (13%) Query: 48 LVMENELFCSGVLVHPQWVLSAAH----CFQNSYTIGLG---LHSLEADQEPGSQMVEAS 100 + ++ + +GVL+ VL+ H + + + E E Sbjct: 49 VFVKGQTSATGVLIGKNTVLTNRHIAKFANGDPSKVSFRPSINTDDNGNTETPYGEYEVK 108 Query: 101 LSVRHPEYNRPLLANDLMLIKLDES---VSESDTIRSISIASQ 140 ++ P DL LI+L VS D I I + Sbjct: 109 EILQEP----FGAGVDLALIRLKPDQNGVSLGDKISPAKIGTS 147 >2HRV-A nrPDB Length = 142 Score = 29.4 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 12/47 (25%), Positives = 20/47 (42%), Gaps = 7/47 (14%) Query: 179 SKLYDPLYHPSMFCAGGGHDQKDSCN-GDSGGPLICNGYLQGLVSFG 224 S+ Y ++ + C GD GG L+C + G+V+ G Sbjct: 83 SEYYPKHIQYNLL------IGEGPCEPGDCGGKLLCKHGVIGIVTAG 123 >3W95-A nrPDB Length = 171 Score = 28.2 bits (62), Expect = 3.4, Method: Composition-based stats. Identities = 10/20 (50%), Positives = 13/20 (65%) Query: 205 GDSGGPLICNGYLQGLVSFG 224 GD+GG L C + G+VS G Sbjct: 129 GDAGGILRCQHGVVGIVSTG 148 >4FVB-A nrPDB Length = 152 Score = 28.2 bits (62), Expect = 3.5, Method: Composition-based stats. Identities = 10/20 (50%), Positives = 13/20 (65%) Query: 205 GDSGGPLICNGYLQGLVSFG 224 GD+GG L C + G+VS G Sbjct: 110 GDAGGILRCQHGVVGIVSTG 129 >4NWK-A nrPDB Length = 219 Score = 28.2 bits (62), Expect = 3.7, Method: Composition-based stats. Identities = 9/18 (50%), Positives = 12/18 (66%), Gaps = 1/18 (5%) Query: 204 NGDSGGPLICN-GYLQGL 220 G SGGPL+C G+ G+ Sbjct: 151 KGSSGGPLLCPAGHAVGI 168 >6C2N-A nrPDB Length = 203 Score = 28.2 bits (62), Expect = 3.9, Method: Composition-based stats. Identities = 9/18 (50%), Positives = 12/18 (66%), Gaps = 1/18 (5%) Query: 204 NGDSGGPLICN-GYLQGL 220 G SGGPL+C G+ G+ Sbjct: 157 KGSSGGPLLCPAGHAVGI 174 >4B6E-A nrPDB Length = 683 Score = 28.2 bits (62), Expect = 4.0, Method: Composition-based stats. Identities = 9/18 (50%), Positives = 13/18 (72%), Gaps = 1/18 (5%) Query: 204 NGDSGGPLIC-NGYLQGL 220 G SGGPL+C +G+ G+ Sbjct: 171 KGSSGGPLLCPSGHAVGI 188 >2M5T-A nrPDB Length = 142 Score = 27.8 bits (61), Expect = 4.1, Method: Composition-based stats. Identities = 10/47 (21%), Positives = 21/47 (44%), Gaps = 7/47 (14%) Query: 179 SKLYDPLYHPSMFCAGGGHDQKDSCN-GDSGGPLICNGYLQGLVSFG 224 ++ Y ++ + C GD+GG L+C + G+++ G Sbjct: 82 TQYYPKHIQYNLL------IGEGPCVPGDAGGKLLCRHGVIGIITAG 122 >3H7V-A nrPDB Length = 330 Score = 27.8 bits (61), Expect = 4.2, Method: Composition-based stats. Identities = 20/96 (20%), Positives = 33/96 (34%), Gaps = 11/96 (11%) Query: 67 LSAAHCFQNSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESV 126 L+ A Q + G++ L + E G V P + L D+ L + Sbjct: 16 LTTA---QGVWRSRSGIY-LRLEDEQGQ--VGYGEIAPLPGWGSETLNADIALCQ-QLPG 68 Query: 127 SESDTIRSISIASQCPTAGNSCLVSGWGLLANGRMP 162 + I +I P A + W + GR+P Sbjct: 69 HLTPEIM-ATIPEALPAA-QFGFATAW--QSVGRLP 100 >6FE6-A nrPDB Length = 165 Score = 27.8 bits (61), Expect = 4.6, Method: Composition-based stats. Identities = 9/18 (50%), Positives = 13/18 (72%), Gaps = 1/18 (5%) Query: 204 NGDSGGPLIC-NGYLQGL 220 G SGGPL+C +G+ G+ Sbjct: 115 KGSSGGPLLCPSGHAVGI 132 >4NSY-A nrPDB Length = 275 Score = 27.8 bits (61), Expect = 4.6, Method: Composition-based stats. Identities = 10/33 (30%), Positives = 17/33 (51%), Gaps = 6/33 (18%) Query: 46 AALVMENELFCSGVLVHPQ------WVLSAAHC 72 AA + ++C+G LV+ + L+A HC Sbjct: 26 AAYSKQGTMWCTGSLVNNSANDKKMYFLTANHC 58 >4U01-A nrPDB Length = 203 Score = 27.8 bits (61), Expect = 5.1, Method: Composition-based stats. Identities = 9/18 (50%), Positives = 13/18 (72%), Gaps = 1/18 (5%) Query: 204 NGDSGGPLIC-NGYLQGL 220 G SGGPL+C +G+ G+ Sbjct: 137 KGSSGGPLLCPSGHAVGI 154 >4K8B-A nrPDB Length = 181 Score = 27.8 bits (61), Expect = 5.2, Method: Composition-based stats. Identities = 9/18 (50%), Positives = 13/18 (72%), Gaps = 1/18 (5%) Query: 204 NGDSGGPLIC-NGYLQGL 220 G SGGPL+C +G+ G+ Sbjct: 136 KGSSGGPLLCPSGHAVGI 153 >4EXK-A nrPDB Length = 487 Score = 27.4 bits (60), Expect = 5.4, Method: Composition-based stats. Identities = 9/33 (27%), Positives = 15/33 (45%), Gaps = 2/33 (6%) Query: 212 ICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFT 244 + L+GL + P + VPG YT + + Sbjct: 420 VARENLKGL--WDYGPLKKENVPGKYTQVITYR 450 >1HPG-A nrPDB Length = 187 Score = 27.4 bits (60), Expect = 5.7, Method: Composition-based stats. Identities = 12/58 (20%), Positives = 19/58 (32%), Gaps = 9/58 (15%) Query: 179 SKLYDPLYHPSMFCAGGGHD------QKDSCN--GDSGGPLICNGYLQGLVSFGKAPC 228 +K+ G + +C+ GDSGG G+ S G + C Sbjct: 107 TKVTSGTVTAVNVTVNYGDGPVYNMVRTTACSAGGDSGGAHFAGSVALGIHS-GSSGC 163 >5MRT-A nrPDB Length = 205 Score = 27.1 bits (59), Expect = 8.2, Method: Composition-based stats. Identities = 14/28 (50%), Positives = 15/28 (53%), Gaps = 1/28 (3%) Query: 204 NGDSGGP-LICNGYLQGLVSFGKAPCGQ 230 GDSGG + G QGL S G P GQ Sbjct: 146 RGDSGGSWITAAGQAQGLTSGGNLPAGQ 173 >5VAI-R nrPDB Length = 461 Score = 26.7 bits (58), Expect = 9.4, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 15/45 (33%), Gaps = 8/45 (17%) Query: 211 LICNGYLQGLVSFGKAPCGQVGVPGVYTNLCK--FTEWIEKTVQA 253 L CN F C G PG + N+ + W +Q Sbjct: 99 LFCNRT------FDDYACWPDGAPGSFVNVSCPWYLPWASNVLQG 137 >5NX2-A nrPDB Length = 422 Score = 26.7 bits (58), Expect = 9.5, Method: Composition-based stats. Identities = 10/38 (26%), Positives = 14/38 (36%), Gaps = 8/38 (21%) Query: 211 LICNGYLQGLVSFGKAPCGQVGVPGVYTNLCK--FTEW 246 L CN F + C G PG + N+ + W Sbjct: 41 LFCNRT------FDEYACWPDGEPGSFVNVSCPWYLPW 72 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.313 0.162 0.601 Lambda K H 0.267 0.0500 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,064,755 Number of Sequences: 36641 Number of extensions: 550558 Number of successful extensions: 2615 Number of sequences better than 10.0: 194 Number of HSP's better than 10.0 without gapping: 324 Number of HSP's successfully gapped in prelim test: 34 Number of HSP's that attempted gapping in prelim test: 1030 Number of HSP's gapped (non-prelim): 375 length of query: 254 length of database: 10,336,785 effective HSP length: 95 effective length of query: 159 effective length of database: 6,855,890 effective search space: 1090086510 effective search space used: 1090086510 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 59 (27.0 bits)