BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9Y2L1 (958 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6D6Q-K nrPDB 1988 0.0 2VNU-D nrPDB 625 e-179 4PMW-A nrPDB 379 e-105 4RO1-B nrPDB 340 1e-93 5XGU-B nrPDB 186 4e-47 2ID0-A nrPDB 110 2e-24 2R7F-A nrPDB 86 7e-17 1XDP-A nrPDB 35 0.12 6F4A-A nrPDB 34 0.39 3W34-A nrPDB 32 1.2 6HIZ-Cg nrPDB 31 2.7 4HWG-A nrPDB 31 3.0 6MUU-A nrPDB 29 9.7 >6D6Q-K nrPDB Length = 960 Score = 1988 bits (5151), Expect = 0.0, Method: Compositional matrix adjust. Identities = 954/958 (99%), Positives = 957/958 (99%) Query: 1 MLKSKTFLKKTRAGGVMKIVREHYLRDDIGCGAPGCAACGGAHEGPALEPQPQDPASSVC 60 MLKSKTFLKKTRAGGVMKIVREHYLRDDIGCGAPGCAACGGAHEGPALEPQPQDPASSVC Sbjct: 3 MLKSKTFLKKTRAGGVMKIVREHYLRDDIGCGAPGCAACGGAHEGPALEPQPQDPASSVC 62 Query: 61 PQPHYLLPDTNVLLHQIDVLEDPAIRNVIVLQTVLQEVRNRSAPVYKRIRDVTNNQEKHF 120 PQPHYLLPDTNVLLHQIDVLEDPAIRNVIVLQTVLQEVRNRSAPVYKRIRDVTNNQEKHF Sbjct: 63 PQPHYLLPDTNVLLHQIDVLEDPAIRNVIVLQTVLQEVRNRSAPVYKRIRDVTNNQEKHF 122 Query: 121 YTFTNEHHRETYVEQEQGENANDRNDRAIRVAAKWYNEHLKKMSADNQLQVIFITNDRRN 180 YTFTNEHHRETYVEQEQGENANDRN+RAIRVAAKWYNEHLKKMSADNQLQVIFITNDRRN Sbjct: 123 YTFTNEHHRETYVEQEQGENANDRNNRAIRVAAKWYNEHLKKMSADNQLQVIFITNDRRN 182 Query: 181 KEKAIEEGIPAFTCEEYVKSLTANPELIDRLACLSEEGNEIESGKIIFSEHLPLSKLQQG 240 KEKAIEEGIPAFTCEEYVKSLTANPELIDRLACLSEEGNEIESGKIIFSEHLPLSKLQQG Sbjct: 183 KEKAIEEGIPAFTCEEYVKSLTANPELIDRLACLSEEGNEIESGKIIFSEHLPLSKLQQG 242 Query: 241 IKSGTYLQGTFRASRENYLEATVWIHGDNEENKEIILQGLKHLNRAVHEDIVAVELLPKS 300 IKSGTYLQGTFRASRENYLEATVWIHGD+EENKEIILQGLKHLNRAVHEDIVAVELLPKS Sbjct: 243 IKSGTYLQGTFRASRENYLEATVWIHGDSEENKEIILQGLKHLNRAVHEDIVAVELLPKS 302 Query: 301 QWVAPSSVVLHDEGQNEEDVEKEEETERMLKTAVSEKMLKPTGRVVGIIKRNWRPYCGML 360 QWVAPSSVVLHDEGQNEEDVEKEEETERMLKTAVSEKMLKPTGRVVGIIKRNWRPYCGML Sbjct: 303 QWVAPSSVVLHDEGQNEEDVEKEEETERMLKTAVSEKMLKPTGRVVGIIKRNWRPYCGML 362 Query: 361 SKSDIKESRRHLFTPADKRIPRIRIETRQASTLEGRRIIVAIDGWPRNSRYPNGHFVRNL 420 SKSDIKESRRHLFTPADKRIPRIRIETRQASTLEGRRIIVAIDGWPRNSRYPNGHFVRNL Sbjct: 363 SKSDIKESRRHLFTPADKRIPRIRIETRQASTLEGRRIIVAIDGWPRNSRYPNGHFVRNL 422 Query: 421 GDVGEKETETEVLLLEHDVPHQPFSQAVLSFLPKMPWSITEKDMKNREDLRHLCICSVDP 480 GDVGEKETETEVLLLEHDVPHQPFSQAVLSFLPKMPWSITEKDMKNREDLRHLCICSVDP Sbjct: 423 GDVGEKETETEVLLLEHDVPHQPFSQAVLSFLPKMPWSITEKDMKNREDLRHLCICSVDP 482 Query: 481 PGCTDIDDALHCRELENGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKRIDMV 540 PGCTDI+DALHCRELENGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKRIDMV Sbjct: 483 PGCTDINDALHCRELENGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKRIDMV 542 Query: 541 PELLSSNLCSLKCDVDRLAFSCIWEMNHNAEILKTKFTKSVINSKASLTYAEAQLRIDSA 600 PELLSSNLCSLKCDVDRLAFSCIWEMNHNAEILKTKFTKSVINSKASLTYAEAQLRIDSA Sbjct: 543 PELLSSNLCSLKCDVDRLAFSCIWEMNHNAEILKTKFTKSVINSKASLTYAEAQLRIDSA 602 Query: 601 NMNDDITTSLRGLNKLAKILKKRRIEKGALTLSSPEVRFHMDSETHDPIDLQTKELRETN 660 NMNDDITTSLRGLNKLAKILKKRRIEKGALTLSSPEVRFHMDSETHDPIDLQTKELRETN Sbjct: 603 NMNDDITTSLRGLNKLAKILKKRRIEKGALTLSSPEVRFHMDSETHDPIDLQTKELRETN 662 Query: 661 SMVEEFMLLANISVAKKIHEEFSEHALLRKHPAPPPSNYEILVKAARSRNLEIKTDTAKS 720 SMVEEFMLLANISVAKKIHEEFSEHALLRKHPAPPPSNYEILVKAARSRNLEIKTDTAKS Sbjct: 663 SMVEEFMLLANISVAKKIHEEFSEHALLRKHPAPPPSNYEILVKAARSRNLEIKTDTAKS 722 Query: 721 LAESLDQAESPTFPYLNTLLRILATRCMMQAVYFCSGMDNDFHHYGLASPIYTHFTSPIR 780 LAESLDQAESPTFPYLNTLLRILATRCMMQAVYFCSGMDNDFHHYGLASPIYTHFTSPIR Sbjct: 723 LAESLDQAESPTFPYLNTLLRILATRCMMQAVYFCSGMDNDFHHYGLASPIYTHFTSPIR 782 Query: 781 RYADVIVHRLLAVAIGADCTYPELTDKHKLADICKNLNFRHKMAQYAQRASVAFHTQLFF 840 RYADVIVHRLLAVAIGADCTYPELTDKHKLADICKNLNFRHKMAQYAQRASVAFHTQLFF Sbjct: 783 RYADVIVHRLLAVAIGADCTYPELTDKHKLADICKNLNFRHKMAQYAQRASVAFHTQLFF 842 Query: 841 KSKGIVSEEAYILFVRKNAIVVLIPKYGLEGTVFFEEKDKPNPQLIYDDEIPSLKIEDTV 900 KS GIVSEEAYILFVRKNAIVVLIPKYGLEGTVFFEEKDKPNPQLIYDDEIPSLKIEDTV Sbjct: 843 KSNGIVSEEAYILFVRKNAIVVLIPKYGLEGTVFFEEKDKPNPQLIYDDEIPSLKIEDTV 902 Query: 901 FHVFDKVKVKIMLDSSNLQHQKIRMSLVEPQIPGISIPTDTSNMDLNGPKKKKMKLGK 958 FHVFDKVKVKIMLDSSNLQHQKIRMSLVEPQIPGISIPTDTSNMDLNGPKKKKMKLGK Sbjct: 903 FHVFDKVKVKIMLDSSNLQHQKIRMSLVEPQIPGISIPTDTSNMDLNGPKKKKMKLGK 960 >2VNU-D nrPDB Length = 760 Score = 625 bits (1612), Expect = e-179, Method: Compositional matrix adjust. Identities = 333/733 (45%), Positives = 474/733 (64%), Gaps = 53/733 (7%) Query: 228 FSEHLPLSKLQQGIKSGTYLQGTFRASRENYLEATVWIHGDNEENKEIILQGLKHLNRAV 287 F E+ +++ G+K+G QG + S N+LE +V + +K +++ G K+LNRA Sbjct: 14 FPEYYSTARVMGGLKNGVLYQGNIQISEYNFLEGSVSLP---RFSKPVLIVGQKNLNRAF 70 Query: 288 HEDIVAVELLPKSQWVAPSSVVLHDE------------GQNEEDVEKEEET-------ER 328 + D V VELLP+S+W APSS+VL E G ++++ E T R Sbjct: 71 NGDQVIVELLPQSEWKAPSSIVLDSEHFDVNDNPDIEAGDDDDNNESSSNTTVISDKQRR 130 Query: 329 MLK----TAVSEKMLKPTGRVVGIIKRNWRPYCGMLSKSDI---KESRRHLFTP-ADKRI 380 +L A K ++PT +VV I +R+WR Y G L+ S + S +++F DK + Sbjct: 131 LLAKDAMIAQRSKKIQPTAKVVYIQRRSWRQYVGQLAPSSVDPQSSSTQNVFVILMDKCL 190 Query: 381 PRIRIETRQASTLEGRRIIVAIDGWPRNSRYPNGHFVRNLGDVGEKETETEVLLLEHDVP 440 P++RI TR+A+ L +RI+++ID WP +YP GHFVR+LG + + ETE LLLEHDV Sbjct: 191 PKVRIRTRRAAELLDKRIVISIDSWPTTHKYPLGHFVRDLGTIESAQAETEALLLEHDVE 250 Query: 441 HQPFSQAVLSFLP------KMPWSITEKD-------MKNREDLRHLCICSVDPPGCTDID 487 ++PFS+ VL LP K P + + + + R+DLR ICS+DPPGC DI+ Sbjct: 251 YRPFSKKVLECLPAEGHDWKAPTKLDDPEAVSKDPLLTKRKDLRDKLICSIDPPGCVDIN 310 Query: 488 DALHCRELENGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKRIDMVPELLSSN 547 DALH ++L NGN EVGVHIADV+HF++PG ALD E A RGT+VYL +KRIDM+P LL ++ Sbjct: 311 DALHAKKLPNGNWEVGVHIADVTHFVKPGTALDAEGAARGTSVYLVDKRIDMLPMLLGTD 370 Query: 548 LCSLKCDVDRLAFSCIWEMNHNAEILKTKFTKSVINSKASLTYAEAQLRIDSANMNDDIT 607 LCSLK VDR AFS IWE++ +A I+ F KSVI S+ + +Y +AQLRID ND++T Sbjct: 371 LCSLKPYVDRFAFSVIWELDDSANIVNVNFMKSVIRSREAFSYEQAQLRIDDKTQNDELT 430 Query: 608 TSLRGLNKLAKILKKRRIEKGALTLSSPEVRFHMDSETHDPIDLQTKELRETNSMVEEFM 667 +R L KL+ LK++R+E GAL L+SPEV+ HMDSET DP +++ K+L TNS+VEEFM Sbjct: 431 MGMRALLKLSVKLKQKRLEAGALNLASPEVKVHMDSETSDPNEVEIKKLLATNSLVEEFM 490 Query: 668 LLANISVAKKIHEEFSEHALLRKHPAPPPSNYEILVKAARSR-NLEIKTDTAKSLAESLD 726 LLANISVA+KI++ F + A+LR+H APP +N+EIL + +R N+ I +++K+LA+SLD Sbjct: 491 LLANISVARKIYDAFPQTAMLRRHAAPPSTNFEILNEMLNTRKNMSISLESSKALADSLD 550 Query: 727 QAESPTFPYLNTLLRILATRCMMQAVYFCSGMDN--DFHHYGLASPIYTHFTSPIRRYAD 784 + P PY NTL+RI++TRCMM A YF SG + DF HYGLA IYTHFTSPIRRY D Sbjct: 551 RCVDPEDPYFNTLVRIMSTRCMMAAQYFYSGAYSYPDFRHYGLAVDIYTHFTSPIRRYCD 610 Query: 785 VIVHRLLAVAIGADCTYPELTDKHKLADICKNLNFRHKMAQYAQRASVAFHTQLFFKSKG 844 V+ HR LA AIG + DK+K+ IC+N+N +H+ AQ+A RAS+ ++ ++ Sbjct: 611 VVAHRQLAGAIGYEPLSLTHRDKNKMDMICRNINRKHRNAQFAGRASIEYYVGQVMRNNE 670 Query: 845 IVSEEAYILFVRKNAIVVLIPKYGLEGTVFFEE-KDKPNPQLIYDDE-----IPSLKIED 898 +E Y++ V N IVVL+PK+G+EG + + + PN + E +P+ + Sbjct: 671 -STETGYVIKVFNNGIVVLVPKFGVEGLIRLDNLTEDPNSAAFDEVEYKLTFVPTNSDKP 729 Query: 899 TVFHVFDKVKVKI 911 +VFDKV+V++ Sbjct: 730 RDVYVFDKVEVQV 742 >4PMW-A nrPDB Length = 770 Score = 379 bits (974), Expect = e-105, Method: Compositional matrix adjust. Identities = 263/773 (34%), Positives = 398/773 (51%), Gaps = 89/773 (11%) Query: 225 KIIFSEHLPLSKLQQGIKSGTYLQGTFRASRENYLEATVWIHGDNEENKEIILQGLKHLN 284 K IF ++ + +G+K GT +QG R + + + EA + + +++I + G+ N Sbjct: 11 KSIFETYMSKEDVSEGLKRGTLIQGVLRINPKKFHEAFI---PSPDGDRDIFIDGVVARN 67 Query: 285 RAVHEDIVAVELLPKSQW--VAPSSVVLHDEGQNEEDVEKE------EETERMLKTA--- 333 RA++ D+V V+LLP+ QW V P S E E D+ +E + +R T+ Sbjct: 68 RALNGDLVVVKLLPEDQWKAVKPESNDKEIEATYEADIPEEGCGDDSDSEDRHGNTSGLV 127 Query: 334 --------VSEKMLKPTGRVVGII-KRNWRPYCGMLSKSDIKES----RRHLFTPADKRI 380 +SEK L+ + +VV I+ K++ R G+L K S + LF+P+D R+ Sbjct: 128 DGVKKLSILSEKSLQKSAKVVYILEKKHSRAATGILKLLADKNSDLFKKYALFSPSDHRV 187 Query: 381 PRIRIETRQ------------ASTLEGRRIIVAIDGWPRNSRYPNGHFVRNLGDVGEKET 428 PRI + + A+TL RII W + + G ++LG GE E Sbjct: 188 PRIYVPLKDCPQDFMTRPKDFANTLFICRII----DWKEDCNFALGQLAKSLGQAGEIEP 243 Query: 429 ETEVLLLEHDVPHQPFSQAVLSFLPK-MPWSITEKDMKNREDLRHLCICSVDPPGCTDID 487 ETE +L E+ V FS VL LP+ +PW+I ++ R DLR CI ++DP D++ Sbjct: 244 ETEGILTEYGVDFSDFSSEVLECLPQSLPWTIPPDEVGKRRDLRKDCIFTIDPSTARDLN 303 Query: 488 DALHCRELENGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKRIDMVPELLSSN 547 DAL CR L +G EVGVHIADVS+F+ G++LD+ +A R T+VYL +K + M+P LL Sbjct: 304 DALACRRLTDGTFEVGVHIADVSYFVPEGSSLDKVAAERATSVYLVQKVVPMLPRLLCEE 363 Query: 548 LCSLKCDVDRLAFSCIWEMNHNAEILKTKFTKSVINSKASLTYAEAQLRIDSANMN---- 603 LCSL D+L FS IW++ +IL+ F +++I S L+Y AQ I++ Sbjct: 364 LCSLNPMTDKLTFSVIWKLTPEGKILEEWFGRTIIRSCTKLSYDHAQSMIENPTEKIPEE 423 Query: 604 -----------DDITTSLRGLNKLAKILKKRRIEKGALTLSSPEVRFHMDSETHDPIDLQ 652 +++ ++ L+ +AK L+++R GAL L ++ F +D ET P Sbjct: 424 ELPPISPEHSVEEVHQAVLNLHSIAKQLRRQRFVDGALRLDQLKLAFTLDHETGLPQGCH 483 Query: 653 TKELRETNSMVEEFMLLANISVAKKIHEEFSEHALLRKHPAPPPSNYEILVKAARSRNLE 712 E R++N +VEEFMLLAN++VA KI F E ALLR+HP P LV+ L Sbjct: 484 IYEYRDSNKLVEEFMLLANMAVAHKIFRTFPEQALLRRHPPPQTKMLSDLVEFCDQMGLP 543 Query: 713 IKTDTAKSLAESLDQAESPTFPYL--NTLLRILATRCMMQAVYFCSGMDND---FHHYGL 767 + +A +L +SL + L +L + +R M A+YFCSGM D F HY L Sbjct: 544 MDVSSAGALNKSLTKTFGDDKYSLARKEVLTNMYSRPMQMALYFCSGMLQDQEQFRHYAL 603 Query: 768 ASPIYTHFTSPIRRYADVIVHRLLAVAIGADCTYPELTDK-----HKLADICKNLNFRHK 822 P+YTHFTSPIRR+ADVIVHRLLA A+G Y E D K AD C N R Sbjct: 604 NVPLYTHFTSPIRRFADVIVHRLLAAALG----YSEQPDVEPDTLQKQADHC---NDRRM 656 Query: 823 MAQYAQRASVAFHTQLFFKSKGIVSEEAYILFVRKNAIVVLIPKYGLEGTVF-------- 874 ++ Q S+ + K G + EA ++ V A VL+ ++G++ ++ Sbjct: 657 ASKRVQELSIGLFFAVLVKESGPLESEAMVMGVLNQAFDVLVLRFGVQKRIYCNALALRS 716 Query: 875 --FEEKDKPNPQLIYDDEIPSLKIEDT--VFHVFDKVKVKIMLDSSNLQHQKI 923 F++ K P+L E L+ E T V +F V V + +++ L++ I Sbjct: 717 YSFQKVGK-KPELTLVWEPDDLEEEPTQQVITIFSLVDVVLQAEATALKYSAI 768 >4RO1-B nrPDB Length = 764 Score = 340 bits (873), Expect = 1e-93, Method: Compositional matrix adjust. Identities = 257/765 (33%), Positives = 389/765 (50%), Gaps = 74/765 (9%) Query: 225 KIIFSEHLPLSKLQQGIKSGTYLQGTFRASRENYLEATVWIHGDNEENKEIILQGLKHLN 284 K ++ + + +++G+KSGT +GT R EN+ A + E+ + + G N Sbjct: 10 KSVYPLYYDSATVKKGLKSGTLFKGTLRI-LENHRSAFACM----EDIPDFYVDGPIARN 64 Query: 285 RAVHEDIVAVELL-------PKSQWVAPSSVVLHDEGQNEEDVEKEEETERM-LKTAVSE 336 RA H D+V VE + KS ++ + + ++E E ER+ +K+ S Sbjct: 65 RAFHNDVVIVEPVMNNDSPTEKSNFLQNGVEKVKIKDHDDELGGAMEHLERLEIKSVASF 124 Query: 337 KMLKPT-GRVVGIIKR-NWRPYCGML-----SKSDI----KESRRHLFTPADKRIPRIRI 385 K T RVV I KR G+L S ++ K+S +F P DKR+P I I Sbjct: 125 KGDSRTRARVVAIEKRAEISKIVGILRAPGWSLKNVEYVSKKSSYAIFIPKDKRLPFITI 184 Query: 386 ETRQASTLEGRRII------------VAIDGWPRNSRYPNGHFVRNLGDVGEKETETEVL 433 S L G I V I W SR+P G LG++ + E T L Sbjct: 185 HKNDLSDLSGENWIENILKHHDQLFSVEITRWSIYSRWPMGVLGEKLGNITDVEAYTNAL 244 Query: 434 LLEHDVPHQPFSQAVLSFLPKMPWSITEKDMKNREDLRHLCICSVDPPGCTDIDDALHCR 493 LLE+ + PFS VL+ LP W I+ +++K R DLR+ I ++DP D+DDA+ CR Sbjct: 245 LLENGISSSPFSDEVLNCLPPDDWIISHEEIKKRRDLRNELIITIDPETARDLDDAVSCR 304 Query: 494 ELENGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKRIDMVPELLSSNLCSLKC 553 L+NG EVGVHIADV+HF++P +ALD+E+A R TTVYL +K I M+P LL LCSL Sbjct: 305 ALDNGTYEVGVHIADVTHFVKPDSALDKEAASRATTVYLVQKAIPMLPPLLCERLCSLNP 364 Query: 554 DVDRLAFSCIWEMNHNA-EILKTKFTKSVINSKASLTYAEAQLRIDSANMND-------- 604 +V+RLAFS W+++ N EI K F K+VI + A L Y+EAQ I+ + +D Sbjct: 365 NVERLAFSVFWKLDSNGKEIGKRWFGKTVIKTCARLAYSEAQGVIEGKSWDDAVGKPIGG 424 Query: 605 -----DITTSLRGLNKLAKILKKRRIEKGALTLSSPEVRFHMDSETHDPIDLQTKELRET 659 D+ TS+ L ++++ L+K R KGA+ ++S E++F +D E P + E + Sbjct: 425 THTPKDVETSILTLCEISRKLRKDRFAKGAVEINSTELKFQLD-EYGMPNKCEVYEQTDA 483 Query: 660 NSMVEEFMLLANISVAKKIHEEFSEHALLRKHPAPPPSNYEILVKAARSRNLEIKTDTAK 719 N ++EEFMLLAN SVA+ I + FS ++LLR+H +P +S N + ++ Sbjct: 484 NHLIEEFMLLANRSVAEHISKNFSNNSLLRRHASPKEKQINEFCHFLKSMNFDFDASSSA 543 Query: 720 SLAESLDQAESPTFPYLNTLLRILATRCMMQAVYFCS---GMDNDFHHYGLASPIYTHFT 776 + S+ + S L L +A R + +A YFC+ G D+HHY L+ YTHFT Sbjct: 544 AFNASMVRLRSTFNEELVELFENMAVRSLNRAEYFCTGDFGEKTDWHHYALSFNHYTHFT 603 Query: 777 SPIRRYADVIVHRLLAVAIGADCTYPELTDKHKLADICKNLNFRHKMAQYAQRASVAFHT 836 SPIRRY D+IVHRLL ++ T P + DK + + + N + + + Q S Sbjct: 604 SPIRRYPDIIVHRLLERSLKN--TSPGI-DKKNCSLVAAHCNEKKEKSTTVQEDSQQLFL 660 Query: 837 QLFFK------SKGIVSEEAYILFVRKNAIVVLIPKYGLEGTVFFEEKDKPNPQLIYDDE 890 ++ K + +A+ + N+I V I +YG+ V D+ ++ D+ Sbjct: 661 SVYIAEYCKKHDKKSMPVQAFATRISGNSIDVYISEYGISNRVDLSSDDRIKSFIVAPDD 720 Query: 891 IPSLKIEDTVFH-------VFDKVKVKIMLDSSNLQHQKIRMSLV 928 S+KI T+F + D+ +V + D S IR SLV Sbjct: 721 -SSVKI--TLFDDSQKTIALTDRFQVYLYSDYSR-TFFSIRCSLV 761 >5XGU-B nrPDB Length = 645 Score = 186 bits (472), Expect = 4e-47, Method: Compositional matrix adjust. Identities = 162/559 (28%), Positives = 256/559 (45%), Gaps = 47/559 (8%) Query: 395 GRRIIVAIDGWPRNSRYPNGHFVRNLGDVGEKETETEVLLLEHDVPHQPFSQAVLSFLPK 454 G ++V + P G V LGD ++ L H++P+ + QAV + Sbjct: 109 GFVVVVELTQRPTRRTKAVGKIVEVLGDNMGTGMAVDIALRTHEIPY-IWPQAVEQQVAG 167 Query: 455 MPWSITEKDMKNREDLRHLCICSVDPPGCTDIDDALHCRELENGNLEVGVHIADVSHFIR 514 + + E+ R DLR L + ++D D DDA++C + G + V IADVS+++R Sbjct: 168 LKEEVPEEAKAGRVDLRDLPLVTIDGEDARDFDDAVYCEKKRGGGWRLWVAIADVSYYVR 227 Query: 515 PGNALDQESARRGTTVYLCEKRIDMVPELLSSNLCSLKCDVDRLAFSCIWEMNHNAEILK 574 P LD+E+ RGT+VY + I M+PE+LS+ LCSL VDRL C ++ + Sbjct: 228 PSTPLDREARNRGTSVYFPSQVIPMLPEVLSNGLCSLNPQVDRLCMVCEMTVSSKGRLTG 287 Query: 575 TKFTKSVINSKASLTYAEA----QLRIDSANMNDDITTSLRGLNKLAKILKKRRIEKGAL 630 KF ++V++S A LTY + Q D + L L+ L K+L K R E+G + Sbjct: 288 YKFYEAVMSSHARLTYTKVWHILQGDQDLREQYAPLVKHLEELHNLYKVLDKAREERGGI 347 Query: 631 TLSSPEVRFHMDSETHDPIDLQTKELRETNSMVEEFMLLANISVAKKIHEEFSEHALLRK 690 + S E +F ++E QT+ + + ++EE M+LANIS A+ + E+ E AL R Sbjct: 348 SFESEEAKFIFNAERRIERIEQTQR-NDAHKLIEECMILANISAARFV-EKAKEPALFRI 405 Query: 691 HPAPPPSNYEILVKAARSRNLEIKTDTA---KSLAESLDQ-AESPTFPYLNTLLRILATR 746 H P LE+ + AE L+ A+ P L T+L R Sbjct: 406 HDKPSTEAITSFRSVLAELGLELPGGNKPEPRDYAELLESVADRPDAEMLQTML----LR 461 Query: 747 CMMQAVYFCSGMDNDFHHYGLASPIYTHFTSPIRRYADVIVHR----LLAVAIGADCTYP 802 M QA+Y + H+GLA Y HFTSPIRRY D+ +HR LLA G Sbjct: 462 SMKQAIY----DPENRGHFGLALQSYAHFTSPIRRYPDLTLHRAIKYLLAKEQGHQGNTT 517 Query: 803 ELTDKH----KLADICKNLNFRHKMAQYAQRASVAFHTQLFFKS------KGIVSE-EAY 851 E H ++ + ++ + + A A R + F KG++S + Sbjct: 518 ETGGYHYSMEEMLQLGQHCSMAERRADEATRDVADWLKCDFMLDQVGNVFKGVISSVTGF 577 Query: 852 ILFVRKNAIVVLIPKYGLEGTVFFEEKDKPNPQLIYDDEIPSLKIEDT--VFHVFDKVKV 909 FVR + + + +G V D N +D L E + + + D+V+V Sbjct: 578 GFFVRLDDLFI-------DGLVHVSSLD--NDYYRFDQVGQRLMGESSGQTYRLGDRVEV 628 Query: 910 KIMLDSSNLQHQKIRMSLV 928 ++ ++ N+ +KI SL+ Sbjct: 629 RV--EAVNMDERKIDFSLI 645 >2ID0-A nrPDB Length = 644 Score = 110 bits (276), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 100/387 (25%), Positives = 174/387 (44%), Gaps = 26/387 (6%) Query: 467 REDLRHLCICSVDPPGCTDIDDALHCRELENGNLEVGVHIADVSHFIRPGNALDQESARR 526 REDL L ++D D+DDAL + L + L++ V IAD + +I G+ LD+ + R Sbjct: 189 REDLTALDFVTIDSASTEDMDDALFAKALPDDKLQLIVAIADPTAWIAEGSKLDKAAKIR 248 Query: 527 GTTVYLCEKRIDMVPELLSSNLCSLKCDVDRLAFSCIWEMNHNAEIL-KTKFTKSVINSK 585 T YL I M+P LS +LCSL+ + R +C ++ + I +F + I SK Sbjct: 249 AFTNYLPGFNIPMLPRELSDDLCSLRANEVRPVLACRMTLSADGTIEDNIEFFAATIESK 308 Query: 586 ASLTYAEAQLRIDSAN----MNDDITTSLRGLNKLAKILKKRRIEKGALTLSSPEVRFHM 641 A L Y + +++ ++ I +R L ++ + + R + P+ RF + Sbjct: 309 AKLVYDQVSDWLENTGDWQPESEAIAEQVRLLAQICQRRGEWRHNHALVFKDRPDYRFIL 368 Query: 642 DSETHDPIDLQTKELRETNSMVEEFMLLANISVAKKIHEEFSEHALLRKHPAPPPSNYEI 701 E + +D+ + R N +VEE M+ ANI A+ + ++ + H P+N + Sbjct: 369 -GEKGEVLDIVAEPRRIANRIVEEAMIAANICAARVLRDKLG-FGIYNVHMGFDPANADA 426 Query: 702 LVKAARSRNLEIKTD---TAKSLAESLDQAESPTFPYLNTLLRILATRCMMQAVYFCSGM 758 L ++ L + + T + + ++ +L++ +R + F Sbjct: 427 LAALLKTHGLHVDAEEVLTLDGFCKLRRELDAQPTGFLDSRIRRFQS--------FAEIS 478 Query: 759 DNDFHHYGLASPIYTHFTSPIRRYADVIVHRLL-AVAIGADCTYPELTDKHKLADICKNL 817 H+GL Y +TSPIR+Y D+I HRLL AV G T P+ +I + Sbjct: 479 TEPGPHFGLGLEAYATWTSPIRKYGDMINHRLLKAVIKGETATRPQ-------DEITVQM 531 Query: 818 NFRHKMAQYAQRASVAFHTQLFFKSKG 844 R ++ + A+R + F K K Sbjct: 532 AERRRLNRMAERDVGDWLYARFLKDKA 558 >2R7F-A nrPDB Length = 469 Score = 85.9 bits (211), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 106/408 (25%), Positives = 167/408 (40%), Gaps = 59/408 (14%) Query: 465 KNREDLRHLCICSVDPPGCTDIDDALHCRELENGNLEVGVHIADVSHFIRPGNALDQESA 524 + R DL HL ++D G D DDA+ +L G + VH+ADV+ + P + LD E+ Sbjct: 79 EERLDLTHLPTFAIDDEGNQDPDDAVGVEDLGGGLTRLWVHVADVAALVAPDSPLDLEAR 138 Query: 525 RRGTTVYLCEKRIDMVP-ELLSSNLCSLKCDVDRLAFSCIWEMNHNAEILKTKFTKSVIN 583 RG T+YL ++ I M+P EL++ L L+ + + NAE + T+ + Sbjct: 139 ARGATLYLPDRTIGMLPDELVAKAGLGLHEVSPALSICLDLDPDGNAEAVDVLLTRVKVQ 198 Query: 584 SKASLTYAEAQLRIDSANMNDDITTSLRGLNKLAKILKKRRIEKGALTLSSPEVRFHMDS 643 L Y EAQ R+++ + T R ++ + +GAL++ PEVR D Sbjct: 199 ---RLAYQEAQARLEAG--EEPFVTLARLARASRRLREG----EGALSIDLPEVRVKADE 249 Query: 644 ETHDPIDLQTKELRETNSMVEEFMLLANISVAKKIHEEFSEHALLRKHPAPPPSNYEILV 703 L E+R ++V+E M LA A I + +E L P + + Sbjct: 250 TGASVFPLPKPEMR---TVVQECMTLAGWGTA--IFADDNEIPL-------PFATQDYPT 297 Query: 704 KAARSRNLEIKTDTAKSLAESLDQAESPTFPYLNTLLRILATRCMMQAVYFCSGMDNDFH 763 + L K+LA + Q SP H Sbjct: 298 REVAGDTLPAMWARRKTLARTRFQ-PSP----------------------------GPHH 328 Query: 764 HYGLASPIYTHFTSPIRRYADVIVHRLL-AVAIGADCTYPELTDKHKLADICKNLNFRHK 822 GL +Y TSP+RRY D++VH+ L A G D L+ K A I ++ Sbjct: 329 GMGLD--LYAQATSPMRRYLDLVVHQQLRAFLAGRD----PLSSKVMAAHIAES-QMNAD 381 Query: 823 MAQYAQRASVAFHTQLFFKSKGIVSEEAYILFVRKNAIVVLIPKYGLE 870 + A+R S HT F ++ +A ++ R +LIP + Sbjct: 382 ATRQAERLSRRHHTLRFIAAQPERVWDAVVVDRRGAQATLLIPDLAFD 429 >1XDP-A nrPDB Length = 687 Score = 35.4 bits (80), Expect = 0.12, Method: Compositional matrix adjust. Identities = 30/100 (30%), Positives = 54/100 (54%), Gaps = 16/100 (16%) Query: 92 QTVLQEVRNRSAPVYKRIRDV---TNNQEKHFYTFTNEHHRETYVEQEQGENANDRN--- 145 + VLQE ++S P+ +R+R + +NN ++ + E R + +EQG N++ R+ Sbjct: 18 ERVLQEAADKSNPLIERMRFLGIYSNNLDEFYKVRFAELKRRIIISEEQGSNSHSRHLLG 77 Query: 146 ---DRAIRVAAKW---YNEHLKKMSADNQLQVIFITNDRR 179 R ++ ++ YNE L +M A NQ IF+ N+R+ Sbjct: 78 KIQSRVLKADQEFDGLYNELLLEM-ARNQ---IFLINERQ 113 >6F4A-A nrPDB Length = 832 Score = 33.9 bits (76), Expect = 0.39, Method: Compositional matrix adjust. Identities = 103/480 (21%), Positives = 178/480 (37%), Gaps = 81/480 (16%) Query: 455 MPWSITEKDMKNREDLRHLCICSVDPPGCTDIDDALHCRELENGNLEVGVHIADVS---- 510 MP +++ D + D+ CI S D +I+D + EL+ + +HIAD + Sbjct: 380 MPTIVSDTDRYDFGDMPVFCIDSED---AHEINDGISIEELDGVRSRIHIHIADPAGLFP 436 Query: 511 ---HFIRPGNALD--QESARRGTTVYLCEKRIDMVPELLSSNLCSL-----KCDVDRLAF 560 + + G + D + S +R T YL + + M+P+ N L K + +F Sbjct: 437 ESFDYTKSGISDDVLRVSLKRAFTTYLPDLVVPMLPKSF-CNRADLGKHDRKTETISFSF 495 Query: 561 SCIWEMNHNAEILKTKFTK--SVINSKASLTY--AEAQLRIDSANMNDDITTSLRGLNKL 616 + + + + F ++++ +TY ++ L D ++ L L+ L Sbjct: 496 ELVNKEDGGLHVDYDTFQVRLGIVSNFPKVTYDKVDSILNGDDNSLPSKQKKQLELLHTL 555 Query: 617 AKILKKRRI------------EKGALTLSSPEVRFHMDSETHDPIDLQTKELRETNSMVE 664 A L +RI KG ++LS + D E P + + T +V Sbjct: 556 ATKLLHKRIHDDNAVVFGDGFNKGLVSLSPDD-----DGELCIPTFYDQSQTKST-LLVS 609 Query: 665 EFMLLANISVAKKIHEEFSEHALLRKHPAPPPSNYEILVKAARSRNLEIKTDTAKSLAES 724 EFM+L N A E K P + + NL + AK+ E Sbjct: 610 EFMILTNKLCAAFFQEN--------KIPG--------VYRCYNGLNL---GNQAKAQFEL 650 Query: 725 L-DQAESPTFPYLNTLLRILATRCMMQAVYFCSGMDNDFHHYGLASPIYTHFTSPIRRYA 783 L + + P L + +I + F H + + Y TSP+RR Sbjct: 651 LKENIKLGKLPSLKDITKISSQLSSSFYSPF------PLPHKMIGNTAYLTVTSPMRRGP 704 Query: 784 DVI----VHRLLAVAIGADCTYPELTDKHKLADICKNLNFRHKMAQYAQRASVAFHTQLF 839 D+I +HR L P + L + R + + QR S + T Sbjct: 705 DLINHLQLHRFLK-------KLPLCFKQEYLDQYVWSFQARADILKIFQRHSSTYWTLKH 757 Query: 840 FKSKGIVSEEAYILFVRKNAIV-VLIPKYGL-EGTVFFEEKDKPNPQLIYDDEIPSLKIE 897 + G + + + V +N V L P+Y GT+ + K P++ D I K+E Sbjct: 758 LEQSGTKTHDVIVTSVPQNGTVNCLFPEYSYARGTLKLDPAMKKIPRI--GDTIRHCKVE 815 >3W34-A nrPDB Length = 211 Score = 32.3 bits (72), Expect = 1.2, Method: Composition-based stats. Identities = 12/20 (60%), Positives = 15/20 (75%) Query: 770 PIYTHFTSPIRRYADVIVHR 789 P++ HF P +RYADVIV R Sbjct: 167 PMHLHFVEPTKRYADVIVPR 186 >6HIZ-Cg nrPDB Length = 498 Score = 30.8 bits (68), Expect = 2.7, Method: Compositional matrix adjust. Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 9/75 (12%) Query: 398 IIVAIDGWPRNS-----RYPNGHFVRNLGDVGEKETETEVLLLEHDVPHQPFSQAVLSFL 452 +++ +DGW S RYP+ F+R L E+ T++ L ++P P S+ LSF+ Sbjct: 281 VVIVVDGWNLFSHETHFRYPHPDFLRGLASF--NESSTDIDLYPQELPRIPASR--LSFV 336 Query: 453 PKMPWSITEKDMKNR 467 + I D N+ Sbjct: 337 RGLNKMILSGDDPNK 351 >4HWG-A nrPDB Length = 385 Score = 30.8 bits (68), Expect = 3.0, Method: Compositional matrix adjust. Identities = 37/137 (27%), Positives = 59/137 (43%), Gaps = 29/137 (21%) Query: 160 LKKMSADNQLQVIFITNDRRNKEKAIEEG----------IPAFTCEEYVKSLTANPELID 209 L+ + + +IF T+ R K EG +PAF+ +YVK L N Sbjct: 229 LQMLIKEYNFLIIFSTHPRTKKRLEDLEGFKELGDKIRFLPAFSFTDYVK-LQMNA---- 283 Query: 210 RLACLSEEGNEIESGKIIFSEHLPLSKLQQ------GIKSGTYLQGTFRASRENYLEATV 263 LS+ G E I+ +LP +++ G+ +GT + F+A R L+A Sbjct: 284 -FCILSDSGTITEEASIL---NLPALNIREAHERPEGMDAGTLIMSGFKAER--VLQAVK 337 Query: 264 WIHGDNEENKEIILQGL 280 I +++ NK QGL Sbjct: 338 TITEEHDNNKRT--QGL 352 >6MUU-A nrPDB Length = 791 Score = 29.3 bits (64), Expect = 9.7, Method: Compositional matrix adjust. Identities = 19/60 (31%), Positives = 27/60 (45%), Gaps = 4/60 (6%) Query: 2 LKSKTFLKKTRAGGVMKIVREHYLRDDIGCGAPGCAACGGAHEGPALEPQPQDPASSVCP 61 LK K ++K + G +K + EH + + C CG LEP DP + VCP Sbjct: 373 LKHKLTVRKLKRFGEIKGLFEHGHTERLAE----CPVCGRELPEGKLEPSASDPETKVCP 428 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6D6Q-K nrPDB 1615 0.0 2VNU-D nrPDB 843 0.0 4PMW-A nrPDB 810 0.0 4RO1-B nrPDB 810 0.0 5XGU-B nrPDB 584 e-167 2ID0-A nrPDB 408 e-114 2R7F-A nrPDB 347 1e-95 Sequences not found previously or not previously below threshold: 6F4A-A nrPDB 125 1e-28 1XDP-A nrPDB 42 0.001 6MUU-A nrPDB 33 0.65 4UZY-A nrPDB 33 0.65 2AFB-A nrPDB 32 0.90 2O8R-A nrPDB 30 3.2 4AW2-A nrPDB 30 4.3 >6D6Q-K nrPDB Length = 960 Score = 1615 bits (4182), Expect = 0.0, Method: Composition-based stats. Identities = 954/958 (99%), Positives = 957/958 (99%) Query: 1 MLKSKTFLKKTRAGGVMKIVREHYLRDDIGCGAPGCAACGGAHEGPALEPQPQDPASSVC 60 MLKSKTFLKKTRAGGVMKIVREHYLRDDIGCGAPGCAACGGAHEGPALEPQPQDPASSVC Sbjct: 3 MLKSKTFLKKTRAGGVMKIVREHYLRDDIGCGAPGCAACGGAHEGPALEPQPQDPASSVC 62 Query: 61 PQPHYLLPDTNVLLHQIDVLEDPAIRNVIVLQTVLQEVRNRSAPVYKRIRDVTNNQEKHF 120 PQPHYLLPDTNVLLHQIDVLEDPAIRNVIVLQTVLQEVRNRSAPVYKRIRDVTNNQEKHF Sbjct: 63 PQPHYLLPDTNVLLHQIDVLEDPAIRNVIVLQTVLQEVRNRSAPVYKRIRDVTNNQEKHF 122 Query: 121 YTFTNEHHRETYVEQEQGENANDRNDRAIRVAAKWYNEHLKKMSADNQLQVIFITNDRRN 180 YTFTNEHHRETYVEQEQGENANDRN+RAIRVAAKWYNEHLKKMSADNQLQVIFITNDRRN Sbjct: 123 YTFTNEHHRETYVEQEQGENANDRNNRAIRVAAKWYNEHLKKMSADNQLQVIFITNDRRN 182 Query: 181 KEKAIEEGIPAFTCEEYVKSLTANPELIDRLACLSEEGNEIESGKIIFSEHLPLSKLQQG 240 KEKAIEEGIPAFTCEEYVKSLTANPELIDRLACLSEEGNEIESGKIIFSEHLPLSKLQQG Sbjct: 183 KEKAIEEGIPAFTCEEYVKSLTANPELIDRLACLSEEGNEIESGKIIFSEHLPLSKLQQG 242 Query: 241 IKSGTYLQGTFRASRENYLEATVWIHGDNEENKEIILQGLKHLNRAVHEDIVAVELLPKS 300 IKSGTYLQGTFRASRENYLEATVWIHGD+EENKEIILQGLKHLNRAVHEDIVAVELLPKS Sbjct: 243 IKSGTYLQGTFRASRENYLEATVWIHGDSEENKEIILQGLKHLNRAVHEDIVAVELLPKS 302 Query: 301 QWVAPSSVVLHDEGQNEEDVEKEEETERMLKTAVSEKMLKPTGRVVGIIKRNWRPYCGML 360 QWVAPSSVVLHDEGQNEEDVEKEEETERMLKTAVSEKMLKPTGRVVGIIKRNWRPYCGML Sbjct: 303 QWVAPSSVVLHDEGQNEEDVEKEEETERMLKTAVSEKMLKPTGRVVGIIKRNWRPYCGML 362 Query: 361 SKSDIKESRRHLFTPADKRIPRIRIETRQASTLEGRRIIVAIDGWPRNSRYPNGHFVRNL 420 SKSDIKESRRHLFTPADKRIPRIRIETRQASTLEGRRIIVAIDGWPRNSRYPNGHFVRNL Sbjct: 363 SKSDIKESRRHLFTPADKRIPRIRIETRQASTLEGRRIIVAIDGWPRNSRYPNGHFVRNL 422 Query: 421 GDVGEKETETEVLLLEHDVPHQPFSQAVLSFLPKMPWSITEKDMKNREDLRHLCICSVDP 480 GDVGEKETETEVLLLEHDVPHQPFSQAVLSFLPKMPWSITEKDMKNREDLRHLCICSVDP Sbjct: 423 GDVGEKETETEVLLLEHDVPHQPFSQAVLSFLPKMPWSITEKDMKNREDLRHLCICSVDP 482 Query: 481 PGCTDIDDALHCRELENGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKRIDMV 540 PGCTDI+DALHCRELENGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKRIDMV Sbjct: 483 PGCTDINDALHCRELENGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKRIDMV 542 Query: 541 PELLSSNLCSLKCDVDRLAFSCIWEMNHNAEILKTKFTKSVINSKASLTYAEAQLRIDSA 600 PELLSSNLCSLKCDVDRLAFSCIWEMNHNAEILKTKFTKSVINSKASLTYAEAQLRIDSA Sbjct: 543 PELLSSNLCSLKCDVDRLAFSCIWEMNHNAEILKTKFTKSVINSKASLTYAEAQLRIDSA 602 Query: 601 NMNDDITTSLRGLNKLAKILKKRRIEKGALTLSSPEVRFHMDSETHDPIDLQTKELRETN 660 NMNDDITTSLRGLNKLAKILKKRRIEKGALTLSSPEVRFHMDSETHDPIDLQTKELRETN Sbjct: 603 NMNDDITTSLRGLNKLAKILKKRRIEKGALTLSSPEVRFHMDSETHDPIDLQTKELRETN 662 Query: 661 SMVEEFMLLANISVAKKIHEEFSEHALLRKHPAPPPSNYEILVKAARSRNLEIKTDTAKS 720 SMVEEFMLLANISVAKKIHEEFSEHALLRKHPAPPPSNYEILVKAARSRNLEIKTDTAKS Sbjct: 663 SMVEEFMLLANISVAKKIHEEFSEHALLRKHPAPPPSNYEILVKAARSRNLEIKTDTAKS 722 Query: 721 LAESLDQAESPTFPYLNTLLRILATRCMMQAVYFCSGMDNDFHHYGLASPIYTHFTSPIR 780 LAESLDQAESPTFPYLNTLLRILATRCMMQAVYFCSGMDNDFHHYGLASPIYTHFTSPIR Sbjct: 723 LAESLDQAESPTFPYLNTLLRILATRCMMQAVYFCSGMDNDFHHYGLASPIYTHFTSPIR 782 Query: 781 RYADVIVHRLLAVAIGADCTYPELTDKHKLADICKNLNFRHKMAQYAQRASVAFHTQLFF 840 RYADVIVHRLLAVAIGADCTYPELTDKHKLADICKNLNFRHKMAQYAQRASVAFHTQLFF Sbjct: 783 RYADVIVHRLLAVAIGADCTYPELTDKHKLADICKNLNFRHKMAQYAQRASVAFHTQLFF 842 Query: 841 KSKGIVSEEAYILFVRKNAIVVLIPKYGLEGTVFFEEKDKPNPQLIYDDEIPSLKIEDTV 900 KS GIVSEEAYILFVRKNAIVVLIPKYGLEGTVFFEEKDKPNPQLIYDDEIPSLKIEDTV Sbjct: 843 KSNGIVSEEAYILFVRKNAIVVLIPKYGLEGTVFFEEKDKPNPQLIYDDEIPSLKIEDTV 902 Query: 901 FHVFDKVKVKIMLDSSNLQHQKIRMSLVEPQIPGISIPTDTSNMDLNGPKKKKMKLGK 958 FHVFDKVKVKIMLDSSNLQHQKIRMSLVEPQIPGISIPTDTSNMDLNGPKKKKMKLGK Sbjct: 903 FHVFDKVKVKIMLDSSNLQHQKIRMSLVEPQIPGISIPTDTSNMDLNGPKKKKMKLGK 960 >2VNU-D nrPDB Length = 760 Score = 843 bits (2178), Expect = 0.0, Method: Composition-based stats. Identities = 333/735 (45%), Positives = 474/735 (64%), Gaps = 53/735 (7%) Query: 228 FSEHLPLSKLQQGIKSGTYLQGTFRASRENYLEATVWIHGDNEENKEIILQGLKHLNRAV 287 F E+ +++ G+K+G QG + S N+LE +V + +K +++ G K+LNRA Sbjct: 14 FPEYYSTARVMGGLKNGVLYQGNIQISEYNFLEGSVSL---PRFSKPVLIVGQKNLNRAF 70 Query: 288 HEDIVAVELLPKSQWVAPSSVVLHDE------------GQNEEDVEKEEET-------ER 328 + D V VELLP+S+W APSS+VL E G ++++ E T R Sbjct: 71 NGDQVIVELLPQSEWKAPSSIVLDSEHFDVNDNPDIEAGDDDDNNESSSNTTVISDKQRR 130 Query: 329 MLK----TAVSEKMLKPTGRVVGIIKRNWRPYCGMLSKSDI---KESRRHLFTP-ADKRI 380 +L A K ++PT +VV I +R+WR Y G L+ S + S +++F DK + Sbjct: 131 LLAKDAMIAQRSKKIQPTAKVVYIQRRSWRQYVGQLAPSSVDPQSSSTQNVFVILMDKCL 190 Query: 381 PRIRIETRQASTLEGRRIIVAIDGWPRNSRYPNGHFVRNLGDVGEKETETEVLLLEHDVP 440 P++RI TR+A+ L +RI+++ID WP +YP GHFVR+LG + + ETE LLLEHDV Sbjct: 191 PKVRIRTRRAAELLDKRIVISIDSWPTTHKYPLGHFVRDLGTIESAQAETEALLLEHDVE 250 Query: 441 HQPFSQAVLSFLP------KMPWSITEKD-------MKNREDLRHLCICSVDPPGCTDID 487 ++PFS+ VL LP K P + + + + R+DLR ICS+DPPGC DI+ Sbjct: 251 YRPFSKKVLECLPAEGHDWKAPTKLDDPEAVSKDPLLTKRKDLRDKLICSIDPPGCVDIN 310 Query: 488 DALHCRELENGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKRIDMVPELLSSN 547 DALH ++L NGN EVGVHIADV+HF++PG ALD E A RGT+VYL +KRIDM+P LL ++ Sbjct: 311 DALHAKKLPNGNWEVGVHIADVTHFVKPGTALDAEGAARGTSVYLVDKRIDMLPMLLGTD 370 Query: 548 LCSLKCDVDRLAFSCIWEMNHNAEILKTKFTKSVINSKASLTYAEAQLRIDSANMNDDIT 607 LCSLK VDR AFS IWE++ +A I+ F KSVI S+ + +Y +AQLRID ND++T Sbjct: 371 LCSLKPYVDRFAFSVIWELDDSANIVNVNFMKSVIRSREAFSYEQAQLRIDDKTQNDELT 430 Query: 608 TSLRGLNKLAKILKKRRIEKGALTLSSPEVRFHMDSETHDPIDLQTKELRETNSMVEEFM 667 +R L KL+ LK++R+E GAL L+SPEV+ HMDSET DP +++ K+L TNS+VEEFM Sbjct: 431 MGMRALLKLSVKLKQKRLEAGALNLASPEVKVHMDSETSDPNEVEIKKLLATNSLVEEFM 490 Query: 668 LLANISVAKKIHEEFSEHALLRKHPAPPPSNYEILVKAARSR-NLEIKTDTAKSLAESLD 726 LLANISVA+KI++ F + A+LR+H APP +N+EIL + +R N+ I +++K+LA+SLD Sbjct: 491 LLANISVARKIYDAFPQTAMLRRHAAPPSTNFEILNEMLNTRKNMSISLESSKALADSLD 550 Query: 727 QAESPTFPYLNTLLRILATRCMMQAVYFCSGMDN--DFHHYGLASPIYTHFTSPIRRYAD 784 + P PY NTL+RI++TRCMM A YF SG + DF HYGLA IYTHFTSPIRRY D Sbjct: 551 RCVDPEDPYFNTLVRIMSTRCMMAAQYFYSGAYSYPDFRHYGLAVDIYTHFTSPIRRYCD 610 Query: 785 VIVHRLLAVAIGADCTYPELTDKHKLADICKNLNFRHKMAQYAQRASVAFHTQLFFKSKG 844 V+ HR LA AIG + DK+K+ IC+N+N +H+ AQ+A RAS+ ++ ++ Sbjct: 611 VVAHRQLAGAIGYEPLSLTHRDKNKMDMICRNINRKHRNAQFAGRASIEYYVGQVMRNN- 669 Query: 845 IVSEEAYILFVRKNAIVVLIPKYGLEGTVFFEE-KDKPNPQLIYDDE-----IPSLKIED 898 +E Y++ V N IVVL+PK+G+EG + + + PN + E +P+ + Sbjct: 670 ESTETGYVIKVFNNGIVVLVPKFGVEGLIRLDNLTEDPNSAAFDEVEYKLTFVPTNSDKP 729 Query: 899 TVFHVFDKVKVKIML 913 +VFDKV+V++ Sbjct: 730 RDVYVFDKVEVQVRS 744 >4PMW-A nrPDB Length = 770 Score = 810 bits (2092), Expect = 0.0, Method: Composition-based stats. Identities = 260/770 (33%), Positives = 395/770 (51%), Gaps = 83/770 (10%) Query: 225 KIIFSEHLPLSKLQQGIKSGTYLQGTFRASRENYLEATVWIHGDNEENKEIILQGLKHLN 284 K IF ++ + +G+K GT +QG R + + + EA + + +++I + G+ N Sbjct: 11 KSIFETYMSKEDVSEGLKRGTLIQGVLRINPKKFHEAFI---PSPDGDRDIFIDGVVARN 67 Query: 285 RAVHEDIVAVELLPKSQW--VAPSSVVLHDEGQNEEDVEKE------EETERMLKTA--- 333 RA++ D+V V+LLP+ QW V P S E E D+ +E + +R T+ Sbjct: 68 RALNGDLVVVKLLPEDQWKAVKPESNDKEIEATYEADIPEEGCGDDSDSEDRHGNTSGLV 127 Query: 334 --------VSEKMLKPTGRVVGI-IKRNWRPYCGMLSKSDIKES----RRHLFTPADKRI 380 +SEK L+ + +VV I K++ R G+L K S + LF+P+D R+ Sbjct: 128 DGVKKLSILSEKSLQKSAKVVYILEKKHSRAATGILKLLADKNSDLFKKYALFSPSDHRV 187 Query: 381 PRIRIETRQ------------ASTLEGRRIIVAIDGWPRNSRYPNGHFVRNLGDVGEKET 428 PRI + + A+TL RII W + + G ++LG GE E Sbjct: 188 PRIYVPLKDCPQDFMTRPKDFANTLFICRII----DWKEDCNFALGQLAKSLGQAGEIEP 243 Query: 429 ETEVLLLEHDVPHQPFSQAVLSFLPK-MPWSITEKDMKNREDLRHLCICSVDPPGCTDID 487 ETE +L E+ V FS VL LP+ +PW+I ++ R DLR CI ++DP D++ Sbjct: 244 ETEGILTEYGVDFSDFSSEVLECLPQSLPWTIPPDEVGKRRDLRKDCIFTIDPSTARDLN 303 Query: 488 DALHCRELENGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKRIDMVPELLSSN 547 DAL CR L +G EVGVHIADVS+F+ G++LD+ +A R T+VYL +K + M+P LL Sbjct: 304 DALACRRLTDGTFEVGVHIADVSYFVPEGSSLDKVAAERATSVYLVQKVVPMLPRLLCEE 363 Query: 548 LCSLKCDVDRLAFSCIWEMNHNAEILKTKFTKSVINSKASLTYAEAQLRIDSANMN---- 603 LCSL D+L FS IW++ +IL+ F +++I S L+Y AQ I++ Sbjct: 364 LCSLNPMTDKLTFSVIWKLTPEGKILEEWFGRTIIRSCTKLSYDHAQSMIENPTEKIPEE 423 Query: 604 -----------DDITTSLRGLNKLAKILKKRRIEKGALTLSSPEVRFHMDSETHDPIDLQ 652 +++ ++ L+ +AK L+++R GAL L ++ F +D ET P Sbjct: 424 ELPPISPEHSVEEVHQAVLNLHSIAKQLRRQRFVDGALRLDQLKLAFTLDHETGLPQGCH 483 Query: 653 TKELRETNSMVEEFMLLANISVAKKIHEEFSEHALLRKHPAPPPSNYEILVKAARSRNLE 712 E R++N +VEEFMLLAN++VA KI F E ALLR+HP P LV+ L Sbjct: 484 IYEYRDSNKLVEEFMLLANMAVAHKIFRTFPEQALLRRHPPPQTKMLSDLVEFCDQMGLP 543 Query: 713 IKTDTAKSLAESLDQAESPTFPYL--NTLLRILATRCMMQAVYFCSGMDND---FHHYGL 767 + +A +L +SL + L +L + +R M A+YFCSGM D F HY L Sbjct: 544 MDVSSAGALNKSLTKTFGDDKYSLARKEVLTNMYSRPMQMALYFCSGMLQDQEQFRHYAL 603 Query: 768 ASPIYTHFTSPIRRYADVIVHRLLAVAIGADCTYPELTDKH--KLADICKNLNFRHKMAQ 825 P+YTHFTSPIRR+ADVIVHRLLA A+G Y E D L + N R ++ Sbjct: 604 NVPLYTHFTSPIRRFADVIVHRLLAAALG----YSEQPDVEPDTLQKQADHCNDRRMASK 659 Query: 826 YAQRASVAFHTQLFFKSKGIVSEEAYILFVRKNAIVVLIPKYGLEGTVF----------F 875 Q S+ + K G + EA ++ V A VL+ ++G++ ++ F Sbjct: 660 RVQELSIGLFFAVLVKESGPLESEAMVMGVLNQAFDVLVLRFGVQKRIYCNALALRSYSF 719 Query: 876 EEKDKPNPQLIYDDEIPSLKIEDT--VFHVFDKVKVKIMLDSSNLQHQKI 923 ++ K P+L E L+ E T V +F V V + +++ L++ I Sbjct: 720 QKVGK-KPELTLVWEPDDLEEEPTQQVITIFSLVDVVLQAEATALKYSAI 768 >4RO1-B nrPDB Length = 764 Score = 810 bits (2091), Expect = 0.0, Method: Composition-based stats. Identities = 253/762 (33%), Positives = 383/762 (50%), Gaps = 68/762 (8%) Query: 225 KIIFSEHLPLSKLQQGIKSGTYLQGTFRASRENYLEATVWIHGDNEENKEIILQGLKHLN 284 K ++ + + +++G+KSGT +GT R EN+ A + E+ + + G N Sbjct: 10 KSVYPLYYDSATVKKGLKSGTLFKGTLRI-LENHRSAFACM----EDIPDFYVDGPIARN 64 Query: 285 RAVHEDIVAVELL-------PKSQWVAPSSVVLHDEGQNEEDVEKEEETERM-LKTAVSE 336 RA H D+V VE + KS ++ + + ++E E ER+ +K+ S Sbjct: 65 RAFHNDVVIVEPVMNNDSPTEKSNFLQNGVEKVKIKDHDDELGGAMEHLERLEIKSVASF 124 Query: 337 KMLKPT-GRVVGIIKR-NWRPYCGML-----SKSDI----KESRRHLFTPADKRIPRIRI 385 K T RVV I KR G+L S ++ K+S +F P DKR+P I I Sbjct: 125 KGDSRTRARVVAIEKRAEISKIVGILRAPGWSLKNVEYVSKKSSYAIFIPKDKRLPFITI 184 Query: 386 ETRQASTLEGRRII------------VAIDGWPRNSRYPNGHFVRNLGDVGEKETETEVL 433 S L G I V I W SR+P G LG++ + E T L Sbjct: 185 HKNDLSDLSGENWIENILKHHDQLFSVEITRWSIYSRWPMGVLGEKLGNITDVEAYTNAL 244 Query: 434 LLEHDVPHQPFSQAVLSFLPKMPWSITEKDMKNREDLRHLCICSVDPPGCTDIDDALHCR 493 LLE+ + PFS VL+ LP W I+ +++K R DLR+ I ++DP D+DDA+ CR Sbjct: 245 LLENGISSSPFSDEVLNCLPPDDWIISHEEIKKRRDLRNELIITIDPETARDLDDAVSCR 304 Query: 494 ELENGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKRIDMVPELLSSNLCSLKC 553 L+NG EVGVHIADV+HF++P +ALD+E+A R TTVYL +K I M+P LL LCSL Sbjct: 305 ALDNGTYEVGVHIADVTHFVKPDSALDKEAASRATTVYLVQKAIPMLPPLLCERLCSLNP 364 Query: 554 DVDRLAFSCIWEMNHNA-EILKTKFTKSVINSKASLTYAEAQLRIDSANMND-------- 604 +V+RLAFS W+++ N EI K F K+VI + A L Y+EAQ I+ + +D Sbjct: 365 NVERLAFSVFWKLDSNGKEIGKRWFGKTVIKTCARLAYSEAQGVIEGKSWDDAVGKPIGG 424 Query: 605 -----DITTSLRGLNKLAKILKKRRIEKGALTLSSPEVRFHMDSETHDPIDLQTKELRET 659 D+ TS+ L ++++ L+K R KGA+ ++S E++F +D E P + E + Sbjct: 425 THTPKDVETSILTLCEISRKLRKDRFAKGAVEINSTELKFQLD-EYGMPNKCEVYEQTDA 483 Query: 660 NSMVEEFMLLANISVAKKIHEEFSEHALLRKHPAPPPSNYEILVKAARSRNLEIKTDTAK 719 N ++EEFMLLAN SVA+ I + FS ++LLR+H +P +S N + ++ Sbjct: 484 NHLIEEFMLLANRSVAEHISKNFSNNSLLRRHASPKEKQINEFCHFLKSMNFDFDASSSA 543 Query: 720 SLAESLDQAESPTFPYLNTLLRILATRCMMQAVYFCSGM---DNDFHHYGLASPIYTHFT 776 + S+ + S L L +A R + +A YFC+G D+HHY L+ YTHFT Sbjct: 544 AFNASMVRLRSTFNEELVELFENMAVRSLNRAEYFCTGDFGEKTDWHHYALSFNHYTHFT 603 Query: 777 SPIRRYADVIVHRLLAVAIGADCTYPELTDKHKLADICKNLNFRHKMAQYAQRASVAFHT 836 SPIRRY D+IVHRLL ++ T P + DK + + + N + + + Q S Sbjct: 604 SPIRRYPDIIVHRLLERSLKN--TSPGI-DKKNCSLVAAHCNEKKEKSTTVQEDSQQLFL 660 Query: 837 QLFFK------SKGIVSEEAYILFVRKNAIVVLIPKYGLEGTVFFEEKDKPNPQLIYDDE 890 ++ K + +A+ + N+I V I +YG+ V D+ ++ D+ Sbjct: 661 SVYIAEYCKKHDKKSMPVQAFATRISGNSIDVYISEYGISNRVDLSSDDRIKSFIVAPDD 720 Query: 891 ----IPSLKIEDTVFHVFDKVKVKIMLDSSNLQHQKIRMSLV 928 I + D+ +V + D S IR SLV Sbjct: 721 SSVKITLFDDSQKTIALTDRFQVYLYSDYSR-TFFSIRCSLV 761 >5XGU-B nrPDB Length = 645 Score = 584 bits (1504), Expect = e-167, Method: Composition-based stats. Identities = 174/646 (26%), Positives = 281/646 (43%), Gaps = 46/646 (7%) Query: 310 LHDEGQNEEDVEKEE------ETERMLKTAVS-EKMLKPTGRVVGIIKRNWRPYCGMLSK 362 L EG+ ++ E +++L + ++ + R+V ++ G Sbjct: 19 LRVEGRKDDLYLSSEQMKTCIHGDQVLAQPLGVDRKGRREARIVRVLVPKTSQIVG---- 74 Query: 363 SDIKESRRHLFTPADKRIPR-IRIETRQ-ASTLEGRRIIVAIDGWPRNSRYPNGHFVRNL 420 E+ P D R+ I I Q G ++V + P G V L Sbjct: 75 RYFTEAGVGFVVPDDSRLSFDILIPPDQIMGARMGFVVVVELTQRPTRRTKAVGKIVEVL 134 Query: 421 GDVGEKETETEVLLLEHDVPHQPFSQAVLSFLPKMPWSITEKDMKNREDLRHLCICSVDP 480 GD ++ L H++P+ + QAV + + + E+ R DLR L + ++D Sbjct: 135 GDNMGTGMAVDIALRTHEIPY-IWPQAVEQQVAGLKEEVPEEAKAGRVDLRDLPLVTIDG 193 Query: 481 PGCTDIDDALHCRELENGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKRIDMV 540 D DDA++C + G + V IADVS+++RP LD+E+ RGT+VY + I M+ Sbjct: 194 EDARDFDDAVYCEKKRGGGWRLWVAIADVSYYVRPSTPLDREARNRGTSVYFPSQVIPML 253 Query: 541 PELLSSNLCSLKCDVDRLAFSCIWEMNHNAEILKTKFTKSVINSKASLTYAEA----QLR 596 PE+LS+ LCSL VDRL C ++ + KF ++V++S A LTY + Q Sbjct: 254 PEVLSNGLCSLNPQVDRLCMVCEMTVSSKGRLTGYKFYEAVMSSHARLTYTKVWHILQGD 313 Query: 597 IDSANMNDDITTSLRGLNKLAKILKKRRIEKGALTLSSPEVRFHMDSETHDPIDLQTKEL 656 D + L L+ L K+L K R E+G ++ S E +F ++E QT+ Sbjct: 314 QDLREQYAPLVKHLEELHNLYKVLDKAREERGGISFESEEAKFIFNAERRIERIEQTQR- 372 Query: 657 RETNSMVEEFMLLANISVAKKIHEEFSEHALLRKHPAPPPSNYEILVKAARSRNLEIKTD 716 + + ++EE M+LANIS A+ + E+ E AL R H P LE+ Sbjct: 373 NDAHKLIEECMILANISAARFV-EKAKEPALFRIHDKPSTEAITSFRSVLAELGLELPGG 431 Query: 717 TA---KSLAESLDQ-AESPTFPYLNTLLRILATRCMMQAVYFCSGMDNDFHHYGLASPIY 772 + AE L+ A+ P L T+L R M QA+Y + H+GLA Y Sbjct: 432 NKPEPRDYAELLESVADRPDAEMLQTML----LRSMKQAIY----DPENRGHFGLALQSY 483 Query: 773 THFTSPIRRYADVIVHR----LLAVAIGADCTYPELTDKH----KLADICKNLNFRHKMA 824 HFTSPIRRY D+ +HR LLA G E H ++ + ++ + + A Sbjct: 484 AHFTSPIRRYPDLTLHRAIKYLLAKEQGHQGNTTETGGYHYSMEEMLQLGQHCSMAERRA 543 Query: 825 QYAQRASVAFHTQLFFKSKGIVSEEAYILFVRKNAIVVLIPKYGLEGTVFFEEKDKPNPQ 884 A R + F + + I V V + ++G V D N Sbjct: 544 DEATRDVADWLKCDFMLDQVGNVFKGVISSVTGFGFFVRLDDLFIDGLVHVSSLD--NDY 601 Query: 885 LIYDDEIPSLKIEDT--VFHVFDKVKVKIMLDSSNLQHQKIRMSLV 928 +D L E + + + D+V+V++ ++ N+ +KI SL+ Sbjct: 602 YRFDQVGQRLMGESSGQTYRLGDRVEVRV--EAVNMDERKIDFSLI 645 >2ID0-A nrPDB Length = 644 Score = 408 bits (1049), Expect = e-114, Method: Composition-based stats. Identities = 114/469 (24%), Positives = 206/469 (43%), Gaps = 31/469 (6%) Query: 467 REDLRHLCICSVDPPGCTDIDDALHCRELENGNLEVGVHIADVSHFIRPGNALDQESARR 526 REDL L ++D D+DDAL + L + L++ V IAD + +I G+ LD+ + R Sbjct: 189 REDLTALDFVTIDSASTEDMDDALFAKALPDDKLQLIVAIADPTAWIAEGSKLDKAAKIR 248 Query: 527 GTTVYLCEKRIDMVPELLSSNLCSLKCDVDRLAFSCIWEMNHNAEIL-KTKFTKSVINSK 585 T YL I M+P LS +LCSL+ + R +C ++ + I +F + I SK Sbjct: 249 AFTNYLPGFNIPMLPRELSDDLCSLRANEVRPVLACRMTLSADGTIEDNIEFFAATIESK 308 Query: 586 ASLTYAEAQLRIDSAN----MNDDITTSLRGLNKLAKILKKRRIEKGALTLSSPEVRFHM 641 A L Y + +++ ++ I +R L ++ + + R + P+ RF + Sbjct: 309 AKLVYDQVSDWLENTGDWQPESEAIAEQVRLLAQICQRRGEWRHNHALVFKDRPDYRFIL 368 Query: 642 DSETHDPIDLQTKELRETNSMVEEFMLLANISVAKKIHEEFSEHALLRKHPAPPPSNYEI 701 E + +D+ + R N +VEE M+ ANI A+ + ++ + H P+N + Sbjct: 369 -GEKGEVLDIVAEPRRIANRIVEEAMIAANICAARVLRDKLG-FGIYNVHMGFDPANADA 426 Query: 702 LVKAARSRNLEIKTD---TAKSLAESLDQAESPTFPYLNTLLRILATRCMMQAVYFCSGM 758 L ++ L + + T + + ++ +L++ +R + F Sbjct: 427 LAALLKTHGLHVDAEEVLTLDGFCKLRRELDAQPTGFLDSRIRRFQS--------FAEIS 478 Query: 759 DNDFHHYGLASPIYTHFTSPIRRYADVIVHRLL-AVAIGADCTYPELTDKHKLADICKNL 817 H+GL Y +TSPIR+Y D+I HRLL AV G T P+ +I + Sbjct: 479 TEPGPHFGLGLEAYATWTSPIRKYGDMINHRLLKAVIKGETATRPQ-------DEITVQM 531 Query: 818 NFRHKMAQYAQRASVAFHTQLFFKSKGIVSEE--AYILFVRKNAIVVLIPKYGLEGTVFF 875 R ++ + A+R + F K K A I+ + + + V + G + Sbjct: 532 AERRRLNRMAERDVGDWLYARFLKDKAGTDTRFAAEIVDISRGGMRVRLVDNGAIAFIPA 591 Query: 876 EEKDKPNPQLIYDDEIPSLKIE-DTVFHVFDKVKVKIMLDSSNLQHQKI 923 +L+ E +++I+ +TV+ V D + V I ++ + I Sbjct: 592 PFLHAVRDELVCSQENGTVQIKGETVYKVTDVIDVTIAE--VRMETRSI 638 >2R7F-A nrPDB Length = 469 Score = 347 bits (890), Expect = 1e-95, Method: Composition-based stats. Identities = 115/486 (23%), Positives = 191/486 (39%), Gaps = 68/486 (13%) Query: 425 EKETETEVLLLEHDV---PHQPFSQAVLSFLPKMPWSITE-KDMKNREDLRHLCICSVDP 480 E LLL V P++ + + L + + + + R DL HL ++D Sbjct: 35 ETPEAAHALLLRLGVWDEARTPYADRLRAALNAVELPVPDFDPAEERLDLTHLPTFAIDD 94 Query: 481 PGCTDIDDALHCRELENGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKRIDMV 540 G D DDA+ +L G + VH+ADV+ + P + LD E+ RG T+YL ++ I M+ Sbjct: 95 EGNQDPDDAVGVEDLGGGLTRLWVHVADVAALVAPDSPLDLEARARGATLYLPDRTIGML 154 Query: 541 P-ELLSSNLCSLKCDVDRLAFSCIWEMNHNAEILKTKFTKSVINSKASLTYAEAQLRIDS 599 P EL++ L L+ + + NAE + T+ + L Y EAQ R+++ Sbjct: 155 PDELVAKAGLGLHEVSPALSICLDLDPDGNAEAVDVLLTRVKVQ---RLAYQEAQARLEA 211 Query: 600 ANMNDDITTSLRGLNKLAKILKKRRIEKGALTLSSPEVRFHMDSETHDPIDLQTKELRET 659 + T R ++ + +GAL++ PEVR D L E+R Sbjct: 212 G--EEPFVTLARLARASRRLREG----EGALSIDLPEVRVKADETGASVFPLPKPEMR-- 263 Query: 660 NSMVEEFMLLANISVAKKIHEEFSEHALLRKHPAPPPSNYEILVKAARSRNLEIKTDTAK 719 ++V+E M LA A I + +E L P + + + L K Sbjct: 264 -TVVQECMTLAGWGTA--IFADDNEIPL-------PFATQDYPTREVAGDTLPAMWARRK 313 Query: 720 SLAESLDQAESPTFPYLNTLLRILATRCMMQAVYFCSGMDNDFHHYGLASPIYTHFTSPI 779 +LA + Q + H+G+ +Y TSP+ Sbjct: 314 TLARTRFQ-------------------------------PSPGPHHGMGLDLYAQATSPM 342 Query: 780 RRYADVIVHRLL-AVAIGADCTYPELTDKHKLADICKNLNFRHKMAQYAQRASVAFHTQL 838 RRY D++VH+ L A G D L+ K A I ++ + A+R S HT Sbjct: 343 RRYLDLVVHQQLRAFLAGRD----PLSSKVMAAHIAES-QMNADATRQAERLSRRHHTLR 397 Query: 839 FFKSKGIVSEEAYILFVRKNAIVVLIPKYGLEGTVFFEEKDKPNPQL---IYDDEIPSLK 895 F ++ +A ++ R +LIP + V P L D ++P ++ Sbjct: 398 FIAAQPERVWDAVVVDRRGAQATLLIPDLAFD--VQVNTPAAPGTALQVQFADIDLPQMR 455 Query: 896 IEDTVF 901 + Sbjct: 456 VRARSV 461 >6F4A-A nrPDB Length = 832 Score = 125 bits (313), Expect = 1e-28, Method: Composition-based stats. Identities = 82/464 (17%), Positives = 159/464 (34%), Gaps = 68/464 (14%) Query: 438 DVPHQPFSQAVLSFL--PKMPWSITEKDMKNREDLRHLCICSVDPPGCTDIDDALHCREL 495 ++P +V L MP +++ D R D + + +D +I+D + EL Sbjct: 361 NIPKSSGISSVEQKLYDTAMPTIVSDTD---RYDFGDMPVFCIDSEDAHEINDGISIEEL 417 Query: 496 ENGNLEVGVHIADVSHFIRP-------GNALD--QESARRGTTVYLCEKRIDMVPELLSS 546 + + +HIAD + G + D + S +R T YL + + M+P+ + Sbjct: 418 DGVRSRIHIHIADPAGLFPESFDYTKSGISDDVLRVSLKRAFTTYLPDLVVPMLPKSFCN 477 Query: 547 --NLCSLKCDVDRLAFSCIWEMNHNAEI-LKTKFTKS---VINSKASLTYAEAQLRI--D 598 +L + ++FS + + + + ++++ +TY + + D Sbjct: 478 RADLGKHDRKTETISFSFELVNKEDGGLHVDYDTFQVRLGIVSNFPKVTYDKVDSILNGD 537 Query: 599 SANMNDDITTSLRGLNKLAKILKKRR------------IEKGALTLSSPEVRFHMDSETH 646 ++ L L+ LA L +R KG ++LS + D E Sbjct: 538 DNSLPSKQKKQLELLHTLATKLLHKRIHDDNAVVFGDGFNKGLVSLSPDD-----DGELC 592 Query: 647 DPIDLQTKELRETNSMVEEFMLLANISVAKKIHEEFSEHALLRKHPAPPPSNYEILVKAA 706 P + ++ +V EFM+L N A +E + R + Sbjct: 593 IPT-FYDQSQTKSTLLVSEFMILTNKLCAAF-FQENKIPGVYRCY--------------- 635 Query: 707 RSRNLEIKTDTAKSLAESLDQAESPTFPYLNTLLRILATRCMMQAVYFCSGMDNDFHHYG 766 L + + + P L + +I + F H Sbjct: 636 --NGLNLGNQAKAQFELLKENIKLGKLPSLKDITKISSQLSSSFYSPF------PLPHKM 687 Query: 767 LASPIYTHFTSPIRRYADVIVHRLLAVAIGADCTYPELTDKHKLADICKNLNFRHKMAQY 826 + + Y TSP+RR D+I H L + + L + R + + Sbjct: 688 IGNTAYLTVTSPMRRGPDLINHLQLHRFLKKLPLCFKQ---EYLDQYVWSFQARADILKI 744 Query: 827 AQRASVAFHTQLFFKSKGIVSEEAYILFVRKNA-IVVLIPKYGL 869 QR S + T + G + + + V +N + L P+Y Sbjct: 745 FQRHSSTYWTLKHLEQSGTKTHDVIVTSVPQNGTVNCLFPEYSY 788 >1XDP-A nrPDB Length = 687 Score = 42.0 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 30/100 (30%), Positives = 54/100 (54%), Gaps = 16/100 (16%) Query: 92 QTVLQEVRNRSAPVYKRIRDV---TNNQEKHFYTFTNEHHRETYVEQEQGENANDRN--- 145 + VLQE ++S P+ +R+R + +NN ++ + E R + +EQG N++ R+ Sbjct: 18 ERVLQEAADKSNPLIERMRFLGIYSNNLDEFYKVRFAELKRRIIISEEQGSNSHSRHLLG 77 Query: 146 ---DRAIRVAAKW---YNEHLKKMSADNQLQVIFITNDRR 179 R ++ ++ YNE L +M A NQ IF+ N+R+ Sbjct: 78 KIQSRVLKADQEFDGLYNELLLEM-ARNQ---IFLINERQ 113 >6MUU-A nrPDB Length = 791 Score = 32.8 bits (73), Expect = 0.65, Method: Composition-based stats. Identities = 20/66 (30%), Positives = 30/66 (45%), Gaps = 4/66 (6%) Query: 2 LKSKTFLKKTRAGGVMKIVREHYLRDDIGCGAPGCAACGGAHEGPALEPQPQDPASSVCP 61 LK K ++K + G +K + EH + + C CG LEP DP + VCP Sbjct: 373 LKHKLTVRKLKRFGEIKGLFEHGHTERLA----ECPVCGRELPEGKLEPSASDPETKVCP 428 Query: 62 QPHYLL 67 + L+ Sbjct: 429 TCNRLV 434 >4UZY-A nrPDB Length = 651 Score = 32.8 bits (73), Expect = 0.65, Method: Composition-based stats. Identities = 39/226 (17%), Positives = 75/226 (33%), Gaps = 31/226 (13%) Query: 612 GLNKLAKILKKRRIEKGALTLSSPEVRFHMDSETHDPIDLQTKELRETNSMVEEFMLLAN 671 L LA+I++K E PE+ +++ + + + + +++E F L A Sbjct: 200 ALKHLAEIIEKAVREH-------PELSVGSNTDGMEVRSVGNSQTLKETALIEAFNLKAA 252 Query: 672 ISVAKKIHEEFSEHALLRKHPAPPPSNYEILVKAARSRNLEIKTDTAKSLAESLDQAESP 731 I K E E AL P V S + + +D + +SP Sbjct: 253 IEYTMKNVEAAKE-AL--TDMPPRAEEELDPVTLHNSALINMDSDPTGGFKKLNFLLQSP 309 Query: 732 TF-PYLNTLLRILATRCMMQAVYFCSGMDNDFHHYG---LASPIYTHFTSPIRRYADVIV 787 F P L +L + + + + Y L+ +Y + + I RY Sbjct: 310 PFPPETFANLLLLYCKPSHGFYDLAADVLAENPQYAGKLLSPDLYDYLQAAIGRY----- 364 Query: 788 HRLLAVAIGADCTYPELTDKHKLADICKNLNFRHKMAQYAQRASVA 833 PE + +++ ++ + Q A +A Sbjct: 365 ------------KSPEEAFRRFDELATRHVEQLRRLTKQIQDARIA 398 >2AFB-A nrPDB Length = 351 Score = 32.4 bits (72), Expect = 0.90, Method: Composition-based stats. Identities = 40/171 (23%), Positives = 73/171 (42%), Gaps = 22/171 (12%) Query: 181 KEKAIEEGIPAFTCEEYVKSLTANPELIDRLACLSEEGNEIESGKIIFSEHLPLSKLQQG 240 KE+A + IP EYV L AN E I+++ +S EG ++++GK+ + +K+ + Sbjct: 186 KEEAQKVMIPFM---EYVDVLIANEEDIEKVLGISVEGLDLKTGKLNREAY---AKIAEE 239 Query: 241 IKSGTYLQG---TFRASRE---NYLEATVWIHGDNEENK--EIILQGLKHLNRAVHEDIV 292 + + T R S NY V+ +G + EI + + ++ Sbjct: 240 VTRKYNFKTVGITLRESISATVNYWSVMVFENGQPHFSNRYEIHIVDRVGAGDSFAGALI 299 Query: 293 AVELL-----PKSQWVAPSSVVLH-DEGQNEEDVEKEEETERMLKTAVSEK 337 L+ K+++ A +S + H G V EE E++ A S + Sbjct: 300 YGSLMGFDSQKKAEFAAAASCLKHTIPGDF--VVLSIEEIEKLASGATSGR 348 >2O8R-A nrPDB Length = 705 Score = 30.5 bits (67), Expect = 3.2, Method: Composition-based stats. Identities = 20/67 (29%), Positives = 33/67 (49%), Gaps = 8/67 (11%) Query: 92 QTVLQEVRNRSAPVYKRIR--DVTNNQEKHFYTFTNEHH------RETYVEQEQGENAND 143 + VL E +R+ PVY RI+ + ++ + FYT +H R E E+ +A+ Sbjct: 22 ERVLMEAADRTLPVYDRIKFLSIFSSNLEEFYTVRVAYHQAVLQKRRDRSEAEEDSDADA 81 Query: 144 RNDRAIR 150 +AIR Sbjct: 82 HILQAIR 88 >4AW2-A nrPDB Length = 437 Score = 30.1 bits (66), Expect = 4.3, Method: Composition-based stats. Identities = 11/18 (61%), Positives = 14/18 (77%) Query: 930 PQIPGISIPTDTSNMDLN 947 P IP +S PTDTSN D++ Sbjct: 356 PYIPEVSSPTDTSNFDVD 373 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.127 0.329 Lambda K H 0.267 0.0382 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 33,081,627 Number of Sequences: 36641 Number of extensions: 1317751 Number of successful extensions: 3779 Number of sequences better than 10.0: 17 Number of HSP's better than 10.0 without gapping: 18 Number of HSP's successfully gapped in prelim test: 21 Number of HSP's that attempted gapping in prelim test: 3674 Number of HSP's gapped (non-prelim): 45 length of query: 958 length of database: 10,336,785 effective HSP length: 106 effective length of query: 852 effective length of database: 6,452,839 effective search space: 5497818828 effective search space used: 5497818828 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 64 (29.4 bits)