BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9Y285 (508 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3L4G-A nrPDB 1048 0.0 1PYS-A nrPDB 137 1e-32 2ALY-A nrPDB 135 5e-32 3PCO-A nrPDB 128 7e-30 2RHQ-A nrPDB 119 4e-27 4P71-C nrPDB 115 3e-26 2ODR-C nrPDB 95 8e-20 2DU7-A nrPDB 89 5e-18 2DU4-A nrPDB 77 1e-14 3TUP-A nrPDB 59 6e-09 3VQX-A nrPDB 35 0.053 2GZM-A nrPDB 33 0.29 5IKJ-A nrPDB 32 0.51 6AQG-A nrPDB 32 0.58 6AQH-A nrPDB 32 0.58 5EP0-A nrPDB 32 0.68 6NRZ-A nrPDB 32 0.86 5HGQ-A nrPDB 31 1.5 4YCV-A nrPDB 30 1.8 2YQ5-A nrPDB 30 1.9 4PRK-A nrPDB 30 3.2 4UP8-A nrPDB 30 3.7 1RR2-A nrPDB 29 5.0 1ADJ-A nrPDB 28 7.7 >3L4G-A nrPDB Length = 508 Score = 1048 bits (2711), Expect = 0.0, Method: Compositional matrix adjust. Identities = 508/508 (100%), Positives = 508/508 (100%) Query: 1 MADGQVAELLLRRLEASDGGLDSAELAAELGMEHQAVVGAVKSLQALGEVIEAELRSTKH 60 MADGQVAELLLRRLEASDGGLDSAELAAELGMEHQAVVGAVKSLQALGEVIEAELRSTKH Sbjct: 1 MADGQVAELLLRRLEASDGGLDSAELAAELGMEHQAVVGAVKSLQALGEVIEAELRSTKH 60 Query: 61 WELTAEGEEIAREGSHEARVFRSIPPEGLAQSELMRLPSGKVGFSKAMSNKWIRVDKSAA 120 WELTAEGEEIAREGSHEARVFRSIPPEGLAQSELMRLPSGKVGFSKAMSNKWIRVDKSAA Sbjct: 61 WELTAEGEEIAREGSHEARVFRSIPPEGLAQSELMRLPSGKVGFSKAMSNKWIRVDKSAA 120 Query: 121 DGPRVFRVVDSMEDEVQRRLQLVRGGQAEKLGEKERSELRKRKLLAEVTLKTYWVSKGSA 180 DGPRVFRVVDSMEDEVQRRLQLVRGGQAEKLGEKERSELRKRKLLAEVTLKTYWVSKGSA Sbjct: 121 DGPRVFRVVDSMEDEVQRRLQLVRGGQAEKLGEKERSELRKRKLLAEVTLKTYWVSKGSA 180 Query: 181 FSTSISKQETELSPEMISSGSWRDRPFKPYNFLAHGVLPDSGHLHPLLKVRSQFRQIFLE 240 FSTSISKQETELSPEMISSGSWRDRPFKPYNFLAHGVLPDSGHLHPLLKVRSQFRQIFLE Sbjct: 181 FSTSISKQETELSPEMISSGSWRDRPFKPYNFLAHGVLPDSGHLHPLLKVRSQFRQIFLE 240 Query: 241 MGFTEMPTDNFIESSFWNFDALFQPQQHPARDQHDTFFLRDPAEALQLPMDYVQRVKRTH 300 MGFTEMPTDNFIESSFWNFDALFQPQQHPARDQHDTFFLRDPAEALQLPMDYVQRVKRTH Sbjct: 241 MGFTEMPTDNFIESSFWNFDALFQPQQHPARDQHDTFFLRDPAEALQLPMDYVQRVKRTH 300 Query: 301 SQGGYGSQGYKYNWKLDEARKNLLRTHTTSASARALYRLAQKKPFTPVKYFSIDRVFRNE 360 SQGGYGSQGYKYNWKLDEARKNLLRTHTTSASARALYRLAQKKPFTPVKYFSIDRVFRNE Sbjct: 301 SQGGYGSQGYKYNWKLDEARKNLLRTHTTSASARALYRLAQKKPFTPVKYFSIDRVFRNE 360 Query: 361 TLDATHLAEFHQIEGVVADHGLTLGHLMGVLREFFTKLGITQLRFKPAYNPYTEPSMEVF 420 TLDATHLAEFHQIEGVVADHGLTLGHLMGVLREFFTKLGITQLRFKPAYNPYTEPSMEVF Sbjct: 361 TLDATHLAEFHQIEGVVADHGLTLGHLMGVLREFFTKLGITQLRFKPAYNPYTEPSMEVF 420 Query: 421 SYHQGLKKWVEVGNSGVFRPEMLLPMGLPENVSVIAWGLSLERPTMIKYGINNIRELVGH 480 SYHQGLKKWVEVGNSGVFRPEMLLPMGLPENVSVIAWGLSLERPTMIKYGINNIRELVGH Sbjct: 421 SYHQGLKKWVEVGNSGVFRPEMLLPMGLPENVSVIAWGLSLERPTMIKYGINNIRELVGH 480 Query: 481 KVNLQMVYDSPLCRLDAEPRPPPTQEAA 508 KVNLQMVYDSPLCRLDAEPRPPPTQEAA Sbjct: 481 KVNLQMVYDSPLCRLDAEPRPPPTQEAA 508 >1PYS-A nrPDB Length = 350 Score = 137 bits (344), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 93/276 (33%), Positives = 137/276 (49%), Gaps = 42/276 (15%) Query: 221 SGHLHPLLKVRSQFRQIFLEMGFTEMPTDNFIESSFWNFDALFQPQQHPARDQHDTFFLR 280 SG LHP+ + + +IF +G+ + +ES F+NFDAL P+ HPARD DTF+L Sbjct: 97 SGGLHPITLMERELVEIFRALGYQAVEGPE-VESEFFNFDALNIPEHHPARDMWDTFWLT 155 Query: 281 DPAEALQLPMDYVQRVKRTHSQGGYGSQGYKYNWKLDEARKNLLRTHTTSASARALYRLA 340 L+ P+ G + +L LLRTHT+ R Y +A Sbjct: 156 GEGFRLEGPL------------------GEEVEGRL------LLRTHTSPMQVR--YMVA 189 Query: 341 QKKPFTPVKYFSIDRVFRNETLDATHLAEFHQIEGVVADHGLTLGHLMGVLREFFTKL-- 398 PF V RVFR E DATH A FHQ+EG+V G+ + HL G + E L Sbjct: 190 HTPPFRIV---VPGRVFRFEQTDATHEAVFHQLEGLVVGEGIAMAHLKGAIYELAQALFG 246 Query: 399 GITQLRFKPAYNPYTEPSMEVFSYHQGLKKWVEVGNSGVFRPEMLLP-------MGLP-- 449 +++RF+P Y P+ EP + + KW+E+G +G+ P++ +GLP Sbjct: 247 PDSKVRFQPVYFPFVEPGAQFAVWWPEGGKWLELGGAGMVHPKVFQAVDAYRERLGLPPA 306 Query: 450 -ENVSVIAWGLSLERPTMIKYGINNIRELVGHKVNL 484 V+ A+GL +ER M++YGI +IR G ++ Sbjct: 307 YRGVTGFAFGLGVERLAMLRYGIPDIRYFFGGRLKF 342 >2ALY-A nrPDB Length = 266 Score = 135 bits (339), Expect = 5e-32, Method: Compositional matrix adjust. Identities = 92/278 (33%), Positives = 136/278 (48%), Gaps = 46/278 (16%) Query: 221 SGHLHPLLKVRSQFRQIFLEMGFTEMPTDNFIESSFWNFDALFQPQQHPARDQHDTFFLR 280 SG LHP+ + + +IF +G+ + +ES F+NFDAL P+ HPARD DTF+L Sbjct: 13 SGGLHPITLMERELVEIFRALGYQAVEGPE-VESEFFNFDALNIPEHHPARDMWDTFWLT 71 Query: 281 DPAEALQLPMDYVQRVKRTHSQGGYGSQGYKYNWKLDEARKN--LLRTHTTSASARALYR 338 +G++ L E + LLRTHT+ R Y Sbjct: 72 --------------------------GEGFRLEGPLGEEVEGRLLLRTHTSPMQVR--YM 103 Query: 339 LAQKKPFTPVKYFSIDRVFRNETLDATHLAEFHQIEGVVADHGLTLGHLMGVLREFFTKL 398 +A PF V RVFR E DATH A FHQ+EG+V G+ + HL G + E L Sbjct: 104 VAHTPPFRIV---VPGRVFRFEQTDATHEAVFHQLEGLVVGEGIAMAHLKGAIYELAQAL 160 Query: 399 --GITQLRFKPAYNPYTEPSMEVFSYHQGLKKWVEVGNSGVFRPEMLLP-------MGLP 449 +++RF+P Y P+ EP + + KW+E+G +G+ P++ +GLP Sbjct: 161 FGPDSKVRFQPVYFPFVEPGAQFAVWWPEGGKWLELGGAGMVHPKVFQAVDAYRERLGLP 220 Query: 450 ---ENVSVIAWGLSLERPTMIKYGINNIRELVGHKVNL 484 V+ A+GL +ER M++YGI +IR G ++ Sbjct: 221 PAYRGVTGFAFGLGVERLAMLRYGIPDIRYFFGGRLKF 258 >3PCO-A nrPDB Length = 327 Score = 128 bits (321), Expect = 7e-30, Method: Compositional matrix adjust. Identities = 86/261 (32%), Positives = 128/261 (49%), Gaps = 50/261 (19%) Query: 220 DSGHLHPLLKVRSQFRQIFLEMGFTEMPTDNFIESSFWNFDALFQPQQHPARDQHDTFFL 279 ++G LHP+ + + F E+GFT + T IE + NFDAL P HPAR HDTF Sbjct: 102 ENGGLHPVTRTIDRIESFFGELGFT-VATGPEIEDDYHNFDALNIPGHHPARADHDTF-- 158 Query: 280 RDPAEALQLPMDYVQRVKRTHSQGGYGSQGYKYNWKLDEARKNLLRTHTTSASARALYRL 339 W D R LLRT T+ R + Sbjct: 159 ----------------------------------W-FDTTR--LLRTQTSGVQIRTM--- 178 Query: 340 AQKKPFTPVKYFSIDRVFRNETLDATHLAEFHQIEGVVADHGLTLGHLMGVLREFFTKL- 398 ++P P++ + RV+RN+ D TH FHQ+EG++ D ++ +L G L +F Sbjct: 179 KAQQP--PIRIIAPGRVYRND-YDQTHTPMFHQMEGLIVDTNISFTNLKGTLHDFLRNFF 235 Query: 399 -GITQLRFKPAYNPYTEPSMEVFSYHQGLKKWVEVGNSGVFRPEMLLPMGL-PENVSVIA 456 Q+RF+P+Y P+TEPS EV + KW+EV G+ P +L +G+ PE S A Sbjct: 236 EEDLQIRFRPSYFPFTEPSAEVDVMGKN-GKWLEVLGCGMVHPNVLRNVGIDPEVYSGFA 294 Query: 457 WGLSLERPTMIKYGINNIREL 477 +G+ +ER TM++YG+ ++R Sbjct: 295 FGMGMERLTMLRYGVTDLRSF 315 >2RHQ-A nrPDB Length = 294 Score = 119 bits (297), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 81/277 (29%), Positives = 125/277 (45%), Gaps = 62/277 (22%) Query: 222 GHLHPLLKVRSQFRQIFLEMGFTEMPTDNFIESSFWNFDALFQPQQHPARDQHDTFFLRD 281 G HPL + + +FL +G+ E+ +E ++NF+AL P+ HPARD D+F++ D Sbjct: 50 GSKHPLTRTVEEIEDLFLGLGY-EIVDGYEVEQDYYNFEALNLPKSHPARDMQDSFYITD 108 Query: 282 PAEALQLPMDYVQRVKRTHSQGGYGSQGYKYNWKLDEARKNLLRTHTTSASARALYRLAQ 341 L+RTHT+ AR + + Sbjct: 109 EI---------------------------------------LMRTHTSPVQARTM---EK 126 Query: 342 KKPFTPVKYFSIDRVFRNETLDATHLAEFHQIEGVVADHGLTLGHLMGVLREFFTKL--G 399 + PVK +V+R ++ DATH +F QIEG+V D + + L G L KL Sbjct: 127 RNGQGPVKIICPGKVYRRDSDDATHSHQFTQIEGLVVDKNIKMSDLKGTLELVAKKLFGA 186 Query: 400 ITQLRFKPAYNPYTEPSMEV-------------FSYHQGLKKWVEVGNSGVFRPEMLLPM 446 ++R +P+Y P+TEPS+EV H G W+E+ +G+ P +L Sbjct: 187 DREIRLRPSYFPFTEPSVEVDVSCFKCKGKGCNVCKHTG---WIEILGAGMVHPNVLEMA 243 Query: 447 GLPEN-VSVIAWGLSLERPTMIKYGINNIRELVGHKV 482 G N S A+G+ +R M+KYGI +IR + V Sbjct: 244 GFDSNEYSGFAFGMGPDRIAMLKYGIEDIRYFYTNDV 280 >4P71-C nrPDB Length = 338 Score = 115 bits (289), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 80/268 (29%), Positives = 123/268 (45%), Gaps = 59/268 (22%) Query: 221 SGHLHPLLKVRSQFRQIFLEMGFTEMPTDNFIESSFWNFDALFQPQQHPARDQHDTFFLR 280 SG LHP+ + + Q F +G+ E+ +E + NF+AL P HPAR HDTF+ Sbjct: 103 SGGLHPVTRTLERIEQCFSRIGY-EVAEGPEVEDDYHNFEALNIPGHHPARAMHDTFY-- 159 Query: 281 DPAEALQLPMDYVQRVKRTHSQGGYGSQGYKYNWKLDEARKNLLRTHTTSASARALYRLA 340 +N + LLRTHT+ R + Sbjct: 160 -------------------------------FNANM------LLRTHTSPVQVRTM---E 179 Query: 341 QKKPFTPVKYFSIDRVFRNETLDATHLAEFHQIEGVVADHGLTLGHLMGVLREFFTKLGI 400 ++P P++ RV+R ++ D TH FHQ+EG++ D G++ L G + EF Sbjct: 180 SQQP--PIRIVCPGRVYRCDS-DLTHSPMFHQVEGLLVDEGVSFADLKGTIEEFLRAFFE 236 Query: 401 TQL--RFKPAYNPYTEPSME-----VFSYHQGLK-----KWVEVGNSGVFRPEMLLPMGL 448 QL RF+P++ P+TEPS E V G + W+EV G+ P +L + Sbjct: 237 KQLEVRFRPSFFPFTEPSAEVDIQCVICSGNGCRVCKQTGWLEVMGCGMVHPNVLRMSNI 296 Query: 449 -PENVSVIAWGLSLERPTMIKYGINNIR 475 PE A+G+ ER M++YG+N++R Sbjct: 297 DPEKFQGFAFGMGAERLAMLRYGVNDLR 324 >2ODR-C nrPDB Length = 701 Score = 94.7 bits (234), Expect = 8e-20, Method: Compositional matrix adjust. Identities = 64/188 (34%), Positives = 93/188 (49%), Gaps = 19/188 (10%) Query: 324 LRTHTTSASARALYRLAQKKPFTPVKYFSIDRVFRNETL-DATHLAEFHQIEGVVADHGL 382 LR+H TS + L KKP P K FSIDR FR E D +HL +H +A G+ Sbjct: 202 LRSHMTSGWFLTVSDLMNKKPL-PFKLFSIDRCFRREQKEDKSHLMTYHSASCAIAGEGV 260 Query: 383 TLGHLMGVLREFFTKLGITQLRFKPA------YNPYTEPSMEVFSYHQGLKKWVEVGNSG 436 + + ++ G T +F P Y P T+ EV++YH LK+W+EV G Sbjct: 261 DINDGKAIAEGLLSQFGFTNFKFIPDEKKSKYYTPETQ--TEVYAYHPKLKEWLEVATFG 318 Query: 437 VFRPEMLLPMGLPENVSVIAWGLSLERPTMIKYGINNIRELV-----GHKVNLQMVYDSP 491 V+ P L G+ +V V+ GL +ER MI ++RE+V HK+N + V + Sbjct: 319 VYSPVALSKYGI--DVPVMNLGLGVERLAMISGNFADVREMVYPQFYEHKLNDRNV--AS 374 Query: 492 LCRLDAEP 499 + +LD P Sbjct: 375 MVKLDKVP 382 >2DU7-A nrPDB Length = 549 Score = 88.6 bits (218), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 57/162 (35%), Positives = 82/162 (50%), Gaps = 12/162 (7%) Query: 324 LRTHTTSASARALYRLAQKKPFTPVKYFSIDRVFRNETL-DATHLAEFHQIEGVVADHGL 382 LR+H TS L L +K+ P+K FSIDR FR E D +HL +H VV + Sbjct: 195 LRSHMTSGWFITLSSLIKKRKL-PLKLFSIDRCFRREQREDRSHLMSYHSASCVVVGEDV 253 Query: 383 TLGHLMGVLREFFTKLGITQLRFKPA------YNPYTEPSMEVFSYHQGLKKWVEVGNSG 436 ++ V + G T+ +FKP Y P T+ EV++YH L +W+EV G Sbjct: 254 SVDDGKVVAEGLLAQFGFTKFKFKPDEKKSKYYTPETQ--TEVYAYHPKLGEWIEVATFG 311 Query: 437 VFRPEMLLPMGLPENVSVIAWGLSLERPTMIKYGINNIRELV 478 V+ P L + +V V+ GL +ER MI YG ++R +V Sbjct: 312 VYSPIALAKYNI--DVPVMNLGLGVERLAMIIYGYEDVRAMV 351 Score = 29.6 bits (65), Expect = 3.0, Method: Compositional matrix adjust. Identities = 12/28 (42%), Positives = 17/28 (60%) Query: 219 PDSGHLHPLLKVRSQFRQIFLEMGFTEM 246 P G HP+++ + RQ +L MGF EM Sbjct: 51 PVYGKPHPVMETIERLRQAYLRMGFEEM 78 >2DU4-A nrPDB Length = 534 Score = 77.4 bits (189), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 54/170 (31%), Positives = 79/170 (46%), Gaps = 20/170 (11%) Query: 324 LRTHTTSASARALYRLAQKKPFTPVKYFSIDRVFRNET-LDATHLAEFHQIEGVVADHGL 382 LR+H T+ L +A K P P+K FSIDR FR E DAT L + V+ D L Sbjct: 183 LRSHMTTGWFITLSHIADKLPL-PIKLFSIDRCFRREQGEDATRLYTYFSASCVLVDEEL 241 Query: 383 TLGHLMGVLREFFTKLGITQLRFKP------AYNPYTEPSMEVFSYHQGL--------KK 428 ++ V + G RF+ Y P T+ EVF++H L Sbjct: 242 SVDDGKAVAEALLRQFGFENFRFRKDEKRSKYYIPDTQ--TEVFAFHPKLVGSSTKYSDG 299 Query: 429 WVEVGNSGVFRPEMLLPMGLPENVSVIAWGLSLERPTMIKYGINNIRELV 478 W+E+ G++ P L +P V+ GL +ER MI YG +++R++V Sbjct: 300 WIEIATFGIYSPTALAEYDIP--YPVMNLGLGVERLAMILYGYDDVRKMV 347 >3TUP-A nrPDB Length = 415 Score = 58.9 bits (141), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 70/297 (23%), Positives = 115/297 (38%), Gaps = 96/297 (32%) Query: 225 HPLLKVRSQFRQIFLEMGFTEMPT------DNF--IESSFWNFDALFQPQQHPARDQHDT 276 HPL ++ + ++ F + T DN + +++ NFD+L P HP+R + D Sbjct: 48 HPLWLIKERVKEHFYKQYVGRFGTPLFSVYDNLSPVVTTWQNFDSLLIPADHPSRKKGDN 107 Query: 277 FFLRDPAEALQLPMDYVQRVKRTHSQGGYGSQGYKYNWKLDEARKNLLRTHTTSASARAL 336 ++L RTH +LR HT++ L Sbjct: 108 YYL-----------------NRTH----------------------MLRAHTSAHQWDLL 128 Query: 337 YRLAQKKPFTPVKYFSIDRVFRNETLDATHLAEFHQIEGV--VADHGLTLG--------- 385 + + + V+R + +D+ H FHQ+E V + H L G Sbjct: 129 HAGLDA-------FLVVGDVYRRDQIDSQHYPIFHQLEAVRLFSKHELFAGIKDGESLQL 181 Query: 386 -------------HLMGVLR--EFFTKLGITQL-----------RFKPAYNPYTEPSMEV 419 H M ++ EF K +T+L R+ Y P+T PS E+ Sbjct: 182 FEQSSRSAHKQETHTMEAVKLVEFDLKQTLTRLMAHLFGDELEIRWVDCYFPFTHPSFEM 241 Query: 420 -FSYHQGLKKWVEVGNSGVFRPEMLLPMGLPENVSVIAWGLSLERPTMIKYGINNIR 475 ++H +W+EV GV +++ G + + A+GL LER MI Y I +IR Sbjct: 242 EINFH---GEWLEVLGCGVMEQQLVNSAGAQDRIG-WAFGLGLERLAMILYDIPDIR 294 >3VQX-A nrPDB Length = 291 Score = 35.4 bits (80), Expect = 0.053, Method: Compositional matrix adjust. Identities = 27/113 (23%), Positives = 50/113 (44%), Gaps = 8/113 (7%) Query: 288 LPMDYVQRVKRTHSQGGYGSQGYKYNWKLDEARKNLLRTHTTSASARALYRLAQKKPFTP 347 +P++Y++R+ + ++ K +++D + LR L +L + P P Sbjct: 105 IPLEYIERMGIDND-----TELSKQIFRVD--KNFCLRPMLAPNLYNYLRKLDRALP-DP 156 Query: 348 VKYFSIDRVFRNETLDATHLAEFHQIEGVVADHGLTLGHLMGVLREFFTKLGI 400 +K F I +R E+ HL EF + G T +L ++ +F LGI Sbjct: 157 IKIFEIGPCYRKESDGKEHLEEFTMLNFCQMGSGCTRENLESIITDFLNHLGI 209 >2GZM-A nrPDB Length = 267 Score = 33.1 bits (74), Expect = 0.29, Method: Compositional matrix adjust. Identities = 25/86 (29%), Positives = 44/86 (51%), Gaps = 18/86 (20%) Query: 30 LGMEHQAVVGAVKSLQALGEVIEAELRSTKHWELTAEGEEIAREGS---HEARVFRSIPP 86 LG H ++G V Q +G+ ++ L + G+E ARE S + +++ Sbjct: 182 LGCTHYPILGPVIK-QVMGDKVQ----------LISSGDETAREVSTILYHSKMLN---- 226 Query: 87 EGLAQSELMRLPSGKVGFSKAMSNKW 112 EG QS+ + L +GK+G K +++KW Sbjct: 227 EGEEQSDHLFLTTGKIGLFKEIASKW 252 >5IKJ-A nrPDB Length = 548 Score = 32.3 bits (72), Expect = 0.51, Method: Compositional matrix adjust. Identities = 30/109 (27%), Positives = 46/109 (42%), Gaps = 15/109 (13%) Query: 112 WIRVDKSAADGPRVFRVVDSMEDEVQ---RRLQLVRGGQAEKLGEKERSELRKRKL---- 164 W ++DK+A D +D +D+++ RRLQ+V KL L + + Sbjct: 432 WTQIDKNALDYNDSADNIDEHKDDLKELPRRLQMV-----SKLSNTYFRCLHDKSVEYVC 486 Query: 165 -LAEVTLKTY--WVSKGSAFSTSISKQETELSPEMISSGSWRDRPFKPY 210 A+V + Y W KG TS K+ T + S +W D F Y Sbjct: 487 PFADVLGRWYEPWFVKGDLNYTSEVKERTSSRLSAVGSENWVDDDFYEY 535 >6AQG-A nrPDB Length = 506 Score = 32.0 bits (71), Expect = 0.58, Method: Compositional matrix adjust. Identities = 13/26 (50%), Positives = 18/26 (69%) Query: 349 KYFSIDRVFRNETLDATHLAEFHQIE 374 + F ++RVFRNE D+TH EF +E Sbjct: 254 RVFELNRVFRNEGSDSTHSPEFSMLE 279 >6AQH-A nrPDB Length = 508 Score = 32.0 bits (71), Expect = 0.58, Method: Compositional matrix adjust. Identities = 13/26 (50%), Positives = 18/26 (69%) Query: 349 KYFSIDRVFRNETLDATHLAEFHQIE 374 + F ++RVFRNE D+TH EF +E Sbjct: 257 RVFELNRVFRNEGADSTHSPEFVMLE 282 >5EP0-A nrPDB Length = 396 Score = 32.0 bits (71), Expect = 0.68, Method: Compositional matrix adjust. Identities = 37/149 (24%), Positives = 67/149 (44%), Gaps = 16/149 (10%) Query: 31 GMEHQAVVGAVKSLQALGEVIEAELRSTKHWELTAE---GEEIAREGSHEARVFRSIP-- 85 G ++Q +G +QA+ VIE+ S +T E G+E+ E H A P Sbjct: 137 GAQYQGFIGNSLPMQAVYRVIESAASSKATVFITGESGTGKEVCAEAIHAASPRHDKPFI 196 Query: 86 -------PEGLAQSELMRLPSGKVGFSKAMSNKWIRVDKSAADGPRVFRVVDSMEDEVQR 138 P+ L +SEL G F+ A + + V+ A +G + + M+ ++Q Sbjct: 197 ALNCAAIPKDLIESELFGHVKG--AFTGASTERQGAVEM-AHNGTLMLDELCEMDLDLQS 253 Query: 139 R-LQLVRGGQAEKLGEKERSELRKRKLLA 166 + L+ ++ G +K+G + S + R + A Sbjct: 254 KLLRFIQTGTYQKVGSSKMSSVDVRFVCA 282 >6NRZ-A nrPDB Length = 534 Score = 31.6 bits (70), Expect = 0.86, Method: Compositional matrix adjust. Identities = 14/30 (46%), Positives = 18/30 (60%) Query: 349 KYFSIDRVFRNETLDATHLAEFHQIEGVVA 378 + + I +VFRNE +D TH EF IE A Sbjct: 270 RVYEIGKVFRNEGIDRTHNPEFTMIEAYAA 299 >5HGQ-A nrPDB Length = 524 Score = 30.8 bits (68), Expect = 1.5, Method: Compositional matrix adjust. Identities = 14/30 (46%), Positives = 18/30 (60%) Query: 349 KYFSIDRVFRNETLDATHLAEFHQIEGVVA 378 + + I RVFRNE +D TH EF E +A Sbjct: 248 RVYEIGRVFRNEGIDQTHNPEFTSCEFYMA 277 >4YCV-A nrPDB Length = 516 Score = 30.4 bits (67), Expect = 1.8, Method: Compositional matrix adjust. Identities = 18/55 (32%), Positives = 24/55 (43%), Gaps = 6/55 (10%) Query: 326 THTTSASARALYRLAQKKPFTPV------KYFSIDRVFRNETLDATHLAEFHQIE 374 TH R+A + P + K + I +VFRNE +D TH EF E Sbjct: 217 THHNDLDLDLYLRIATELPLKMLIVGGIDKVYEIGKVFRNEGIDNTHNPEFTSCE 271 >2YQ5-A nrPDB Length = 343 Score = 30.4 bits (67), Expect = 1.9, Method: Compositional matrix adjust. Identities = 13/45 (28%), Positives = 23/45 (51%) Query: 384 LGHLMGVLREFFTKLGITQLRFKPAYNPYTEPSMEVFSYHQGLKK 428 +GH+ + E F+ +G + + AYNP EP + + LK+ Sbjct: 156 VGHIGSAVAEIFSAMGAKVIAYDVAYNPEFEPFLTYTDFDTVLKE 200 >4PRK-A nrPDB Length = 336 Score = 29.6 bits (65), Expect = 3.2, Method: Compositional matrix adjust. Identities = 12/45 (26%), Positives = 22/45 (48%) Query: 384 LGHLMGVLREFFTKLGITQLRFKPAYNPYTEPSMEVFSYHQGLKK 428 +GH+ + + F+ +G L + YNP EP + + LK+ Sbjct: 154 VGHIGSAVAQIFSAMGAKVLAYDVIYNPEVEPYLTYADFDTVLKE 198 >4UP8-A nrPDB Length = 777 Score = 29.6 bits (65), Expect = 3.7, Method: Compositional matrix adjust. Identities = 13/30 (43%), Positives = 18/30 (60%) Query: 349 KYFSIDRVFRNETLDATHLAEFHQIEGVVA 378 + + I R+FRNE +D TH EF E +A Sbjct: 250 RVYEIGRLFRNEGIDQTHNPEFTTCEFYMA 279 >1RR2-A nrPDB Length = 539 Score = 28.9 bits (63), Expect = 5.0, Method: Compositional matrix adjust. Identities = 13/20 (65%), Positives = 15/20 (75%) Query: 115 VDKSAADGPRVFRVVDSMED 134 VDKSA +G VFRV D+M D Sbjct: 123 VDKSAENGMDVFRVFDAMND 142 >1ADJ-A nrPDB Length = 421 Score = 28.5 bits (62), Expect = 7.7, Method: Compositional matrix adjust. Identities = 30/118 (25%), Positives = 49/118 (41%), Gaps = 15/118 (12%) Query: 319 ARKNLLRTHTTSASARALYRLAQKKPFTPVKYFSIDRVFRNETLDATHLAEFHQI--EGV 376 R LR T+A RA K PV+ + +FR E +FHQ+ E + Sbjct: 73 GRSLTLRPEGTAAMVRAYLEHGMKVWPQPVRLWMAGPMFRAERPQKGRYRQFHQVNYEAL 132 Query: 377 VADHGLTLGHLMGVLREFFTKLGITQLRFKPA----------YNPYTEPSMEVFSYHQ 424 +++ + + +L E +LG+ +L+ K + YN Y EV S H+ Sbjct: 133 GSENPILDAEAVVLLYECLKELGLRRLKVKLSSVGDPEDRARYNAYLR---EVLSPHR 187 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3L4G-A nrPDB 888 0.0 2ALY-A nrPDB 314 4e-86 1PYS-A nrPDB 310 6e-85 3PCO-A nrPDB 288 4e-78 4P71-C nrPDB 286 1e-77 2RHQ-A nrPDB 276 2e-74 2ODR-C nrPDB 217 7e-57 2DU7-A nrPDB 214 7e-56 3TUP-A nrPDB 210 1e-54 2DU4-A nrPDB 200 2e-51 Sequences not found previously or not previously below threshold: 1PYS-B nrPDB 51 1e-06 2ZNJ-A nrPDB 50 2e-06 3VQX-A nrPDB 49 3e-06 5HGQ-A nrPDB 37 0.015 4YCV-A nrPDB 37 0.019 2GZM-A nrPDB 37 0.027 5EP0-A nrPDB 36 0.048 6JP2-A nrPDB 36 0.050 6NRZ-A nrPDB 35 0.063 6AQH-A nrPDB 35 0.072 1ADJ-A nrPDB 35 0.083 4UP8-A nrPDB 35 0.092 6AQG-A nrPDB 34 0.11 1QE0-A nrPDB 34 0.15 4WJ3-M nrPDB 33 0.36 5ELO-A nrPDB 32 0.49 1XHC-A nrPDB 32 0.53 1W0O-A nrPDB 32 0.54 3I7F-A nrPDB 32 0.84 6ILH-A nrPDB 31 0.90 6CHD-A nrPDB 31 0.90 3OD1-A nrPDB 31 1.4 1UG3-A nrPDB 31 1.5 6NUD-J nrPDB 31 1.6 3A74-A nrPDB 31 1.8 2EXX-A nrPDB 30 2.0 2KY4-A nrPDB 30 2.3 2KK6-A nrPDB 30 2.3 3P8T-A nrPDB 30 2.4 6NIY-R nrPDB 30 3.2 5II0-A nrPDB 30 3.2 2H09-A nrPDB 29 4.2 5W25-A nrPDB 29 5.6 >3L4G-A nrPDB Length = 508 Score = 888 bits (2295), Expect = 0.0, Method: Composition-based stats. Identities = 508/508 (100%), Positives = 508/508 (100%) Query: 1 MADGQVAELLLRRLEASDGGLDSAELAAELGMEHQAVVGAVKSLQALGEVIEAELRSTKH 60 MADGQVAELLLRRLEASDGGLDSAELAAELGMEHQAVVGAVKSLQALGEVIEAELRSTKH Sbjct: 1 MADGQVAELLLRRLEASDGGLDSAELAAELGMEHQAVVGAVKSLQALGEVIEAELRSTKH 60 Query: 61 WELTAEGEEIAREGSHEARVFRSIPPEGLAQSELMRLPSGKVGFSKAMSNKWIRVDKSAA 120 WELTAEGEEIAREGSHEARVFRSIPPEGLAQSELMRLPSGKVGFSKAMSNKWIRVDKSAA Sbjct: 61 WELTAEGEEIAREGSHEARVFRSIPPEGLAQSELMRLPSGKVGFSKAMSNKWIRVDKSAA 120 Query: 121 DGPRVFRVVDSMEDEVQRRLQLVRGGQAEKLGEKERSELRKRKLLAEVTLKTYWVSKGSA 180 DGPRVFRVVDSMEDEVQRRLQLVRGGQAEKLGEKERSELRKRKLLAEVTLKTYWVSKGSA Sbjct: 121 DGPRVFRVVDSMEDEVQRRLQLVRGGQAEKLGEKERSELRKRKLLAEVTLKTYWVSKGSA 180 Query: 181 FSTSISKQETELSPEMISSGSWRDRPFKPYNFLAHGVLPDSGHLHPLLKVRSQFRQIFLE 240 FSTSISKQETELSPEMISSGSWRDRPFKPYNFLAHGVLPDSGHLHPLLKVRSQFRQIFLE Sbjct: 181 FSTSISKQETELSPEMISSGSWRDRPFKPYNFLAHGVLPDSGHLHPLLKVRSQFRQIFLE 240 Query: 241 MGFTEMPTDNFIESSFWNFDALFQPQQHPARDQHDTFFLRDPAEALQLPMDYVQRVKRTH 300 MGFTEMPTDNFIESSFWNFDALFQPQQHPARDQHDTFFLRDPAEALQLPMDYVQRVKRTH Sbjct: 241 MGFTEMPTDNFIESSFWNFDALFQPQQHPARDQHDTFFLRDPAEALQLPMDYVQRVKRTH 300 Query: 301 SQGGYGSQGYKYNWKLDEARKNLLRTHTTSASARALYRLAQKKPFTPVKYFSIDRVFRNE 360 SQGGYGSQGYKYNWKLDEARKNLLRTHTTSASARALYRLAQKKPFTPVKYFSIDRVFRNE Sbjct: 301 SQGGYGSQGYKYNWKLDEARKNLLRTHTTSASARALYRLAQKKPFTPVKYFSIDRVFRNE 360 Query: 361 TLDATHLAEFHQIEGVVADHGLTLGHLMGVLREFFTKLGITQLRFKPAYNPYTEPSMEVF 420 TLDATHLAEFHQIEGVVADHGLTLGHLMGVLREFFTKLGITQLRFKPAYNPYTEPSMEVF Sbjct: 361 TLDATHLAEFHQIEGVVADHGLTLGHLMGVLREFFTKLGITQLRFKPAYNPYTEPSMEVF 420 Query: 421 SYHQGLKKWVEVGNSGVFRPEMLLPMGLPENVSVIAWGLSLERPTMIKYGINNIRELVGH 480 SYHQGLKKWVEVGNSGVFRPEMLLPMGLPENVSVIAWGLSLERPTMIKYGINNIRELVGH Sbjct: 421 SYHQGLKKWVEVGNSGVFRPEMLLPMGLPENVSVIAWGLSLERPTMIKYGINNIRELVGH 480 Query: 481 KVNLQMVYDSPLCRLDAEPRPPPTQEAA 508 KVNLQMVYDSPLCRLDAEPRPPPTQEAA Sbjct: 481 KVNLQMVYDSPLCRLDAEPRPPPTQEAA 508 >2ALY-A nrPDB Length = 266 Score = 314 bits (805), Expect = 4e-86, Method: Composition-based stats. Identities = 92/276 (33%), Positives = 137/276 (49%), Gaps = 42/276 (15%) Query: 221 SGHLHPLLKVRSQFRQIFLEMGFTEMPTDNFIESSFWNFDALFQPQQHPARDQHDTFFLR 280 SG LHP+ + + +IF +G+ + +ES F+NFDAL P+ HPARD DTF+L Sbjct: 13 SGGLHPITLMERELVEIFRALGYQAVE-GPEVESEFFNFDALNIPEHHPARDMWDTFWLT 71 Query: 281 DPAEALQLPMDYVQRVKRTHSQGGYGSQGYKYNWKLDEARKNLLRTHTTSASARALYRLA 340 L+ P+ G + +L LLRTHT+ R Y +A Sbjct: 72 GEGFRLEGPL------------------GEEVEGRL------LLRTHTSPMQVR--YMVA 105 Query: 341 QKKPFTPVKYFSIDRVFRNETLDATHLAEFHQIEGVVADHGLTLGHLMGVLREFFTKL-- 398 PF + RVFR E DATH A FHQ+EG+V G+ + HL G + E L Sbjct: 106 HTPPF---RIVVPGRVFRFEQTDATHEAVFHQLEGLVVGEGIAMAHLKGAIYELAQALFG 162 Query: 399 GITQLRFKPAYNPYTEPSMEVFSYHQGLKKWVEVGNSGVFRPEMLLP-------MGLP-- 449 +++RF+P Y P+ EP + + KW+E+G +G+ P++ +GLP Sbjct: 163 PDSKVRFQPVYFPFVEPGAQFAVWWPEGGKWLELGGAGMVHPKVFQAVDAYRERLGLPPA 222 Query: 450 -ENVSVIAWGLSLERPTMIKYGINNIRELVGHKVNL 484 V+ A+GL +ER M++YGI +IR G ++ Sbjct: 223 YRGVTGFAFGLGVERLAMLRYGIPDIRYFFGGRLKF 258 >1PYS-A nrPDB Length = 350 Score = 310 bits (795), Expect = 6e-85, Method: Composition-based stats. Identities = 92/276 (33%), Positives = 137/276 (49%), Gaps = 42/276 (15%) Query: 221 SGHLHPLLKVRSQFRQIFLEMGFTEMPTDNFIESSFWNFDALFQPQQHPARDQHDTFFLR 280 SG LHP+ + + +IF +G+ + +ES F+NFDAL P+ HPARD DTF+L Sbjct: 97 SGGLHPITLMERELVEIFRALGYQAVE-GPEVESEFFNFDALNIPEHHPARDMWDTFWLT 155 Query: 281 DPAEALQLPMDYVQRVKRTHSQGGYGSQGYKYNWKLDEARKNLLRTHTTSASARALYRLA 340 L+ P+ G + +L LLRTHT+ R Y +A Sbjct: 156 GEGFRLEGPL------------------GEEVEGRL------LLRTHTSPMQVR--YMVA 189 Query: 341 QKKPFTPVKYFSIDRVFRNETLDATHLAEFHQIEGVVADHGLTLGHLMGVLREFFTKL-- 398 PF + RVFR E DATH A FHQ+EG+V G+ + HL G + E L Sbjct: 190 HTPPF---RIVVPGRVFRFEQTDATHEAVFHQLEGLVVGEGIAMAHLKGAIYELAQALFG 246 Query: 399 GITQLRFKPAYNPYTEPSMEVFSYHQGLKKWVEVGNSGVFRPEMLLP-------MGLP-- 449 +++RF+P Y P+ EP + + KW+E+G +G+ P++ +GLP Sbjct: 247 PDSKVRFQPVYFPFVEPGAQFAVWWPEGGKWLELGGAGMVHPKVFQAVDAYRERLGLPPA 306 Query: 450 -ENVSVIAWGLSLERPTMIKYGINNIRELVGHKVNL 484 V+ A+GL +ER M++YGI +IR G ++ Sbjct: 307 YRGVTGFAFGLGVERLAMLRYGIPDIRYFFGGRLKF 342 >3PCO-A nrPDB Length = 327 Score = 288 bits (737), Expect = 4e-78, Method: Composition-based stats. Identities = 85/268 (31%), Positives = 128/268 (47%), Gaps = 50/268 (18%) Query: 220 DSGHLHPLLKVRSQFRQIFLEMGFTEMPTDNFIESSFWNFDALFQPQQHPARDQHDTFFL 279 ++G LHP+ + + F E+GFT + T IE + NFDAL P HPAR HDTF+ Sbjct: 102 ENGGLHPVTRTIDRIESFFGELGFT-VATGPEIEDDYHNFDALNIPGHHPARADHDTFW- 159 Query: 280 RDPAEALQLPMDYVQRVKRTHSQGGYGSQGYKYNWKLDEARKNLLRTHTTSASARALYRL 339 D R LLRT T+ R + Sbjct: 160 ------------------------------------FDTTR--LLRTQTSGVQIRTM--- 178 Query: 340 AQKKPFTPVKYFSIDRVFRNETLDATHLAEFHQIEGVVADHGLTLGHLMGVLREFFTKLG 399 K P++ + RV+RN+ D TH FHQ+EG++ D ++ +L G L +F Sbjct: 179 --KAQQPPIRIIAPGRVYRND-YDQTHTPMFHQMEGLIVDTNISFTNLKGTLHDFLRNFF 235 Query: 400 --ITQLRFKPAYNPYTEPSMEVFSYHQGLKKWVEVGNSGVFRPEMLLPMGL-PENVSVIA 456 Q+RF+P+Y P+TEPS EV + KW+EV G+ P +L +G+ PE S A Sbjct: 236 EEDLQIRFRPSYFPFTEPSAEVDVMGKN-GKWLEVLGCGMVHPNVLRNVGIDPEVYSGFA 294 Query: 457 WGLSLERPTMIKYGINNIRELVGHKVNL 484 +G+ +ER TM++YG+ ++R + + Sbjct: 295 FGMGMERLTMLRYGVTDLRSFFENDLRF 322 >4P71-C nrPDB Length = 338 Score = 286 bits (732), Expect = 1e-77, Method: Composition-based stats. Identities = 80/277 (28%), Positives = 125/277 (45%), Gaps = 59/277 (21%) Query: 221 SGHLHPLLKVRSQFRQIFLEMGFTEMPTDNFIESSFWNFDALFQPQQHPARDQHDTFFLR 280 SG LHP+ + + Q F +G+ E+ +E + NF+AL P HPAR HDTF+ Sbjct: 103 SGGLHPVTRTLERIEQCFSRIGY-EVAEGPEVEDDYHNFEALNIPGHHPARAMHDTFY-- 159 Query: 281 DPAEALQLPMDYVQRVKRTHSQGGYGSQGYKYNWKLDEARKNLLRTHTTSASARALYRLA 340 +N + LLRTHT+ R + Sbjct: 160 -------------------------------FNANM------LLRTHTSPVQVRTM---E 179 Query: 341 QKKPFTPVKYFSIDRVFRNETLDATHLAEFHQIEGVVADHGLTLGHLMGVLREFFTKLGI 400 ++P P++ RV+R ++ D TH FHQ+EG++ D G++ L G + EF Sbjct: 180 SQQP--PIRIVCPGRVYRCDS-DLTHSPMFHQVEGLLVDEGVSFADLKGTIEEFLRAFFE 236 Query: 401 TQL--RFKPAYNPYTEPSME-----VFSYHQGLK-----KWVEVGNSGVFRPEMLLPMGL 448 QL RF+P++ P+TEPS E V G + W+EV G+ P +L + Sbjct: 237 KQLEVRFRPSFFPFTEPSAEVDIQCVICSGNGCRVCKQTGWLEVMGCGMVHPNVLRMSNI 296 Query: 449 -PENVSVIAWGLSLERPTMIKYGINNIRELVGHKVNL 484 PE A+G+ ER M++YG+N++R + + Sbjct: 297 DPEKFQGFAFGMGAERLAMLRYGVNDLRLFFDNDLRF 333 >2RHQ-A nrPDB Length = 294 Score = 276 bits (705), Expect = 2e-74, Method: Composition-based stats. Identities = 80/276 (28%), Positives = 125/276 (45%), Gaps = 56/276 (20%) Query: 222 GHLHPLLKVRSQFRQIFLEMGFTEMPTDNFIESSFWNFDALFQPQQHPARDQHDTFFLRD 281 G HPL + + +FL +G+ E+ +E ++NF+AL P+ HPARD D+F++ D Sbjct: 50 GSKHPLTRTVEEIEDLFLGLGY-EIVDGYEVEQDYYNFEALNLPKSHPARDMQDSFYITD 108 Query: 282 PAEALQLPMDYVQRVKRTHSQGGYGSQGYKYNWKLDEARKNLLRTHTTSASARALYRLAQ 341 L+RTHT+ AR + + Sbjct: 109 EI---------------------------------------LMRTHTSPVQARTM---EK 126 Query: 342 KKPFTPVKYFSIDRVFRNETLDATHLAEFHQIEGVVADHGLTLGHLMGVLREFFTKL--G 399 + PVK +V+R ++ DATH +F QIEG+V D + + L G L KL Sbjct: 127 RNGQGPVKIICPGKVYRRDSDDATHSHQFTQIEGLVVDKNIKMSDLKGTLELVAKKLFGA 186 Query: 400 ITQLRFKPAYNPYTEPSMEVF-----SYHQGLK-----KWVEVGNSGVFRPEMLLPMGLP 449 ++R +P+Y P+TEPS+EV +G W+E+ +G+ P +L G Sbjct: 187 DREIRLRPSYFPFTEPSVEVDVSCFKCKGKGCNVCKHTGWIEILGAGMVHPNVLEMAGFD 246 Query: 450 EN-VSVIAWGLSLERPTMIKYGINNIRELVGHKVNL 484 N S A+G+ +R M+KYGI +IR + V Sbjct: 247 SNEYSGFAFGMGPDRIAMLKYGIEDIRYFYTNDVRF 282 >2ODR-C nrPDB Length = 701 Score = 217 bits (553), Expect = 7e-57, Method: Composition-based stats. Identities = 85/333 (25%), Positives = 125/333 (37%), Gaps = 57/333 (17%) Query: 217 VLPDSGHLHPLLKVRSQFRQIFLEMGFTEMPTDNFIE--SSFWNF--------DALFQPQ 266 + P G HP+ RQ +L MGF E ++ + F D F Sbjct: 57 IKPVFGKTHPVNDTIENLRQAYLRMGFEEYINPVIVDERDIYKQFGPEAMAVLDRCFYLA 116 Query: 267 QHPARDQH--DTFFLRDPAEALQLPMDYVQRVKRTHSQGGYGSQGYKYNWKLDEA----- 319 P D D + +++ K H G ++ A Sbjct: 117 GLPRPDVGLSDEKISQIEKLGIKVSEHKESLQKILHGYKKGTLDGDDLVLEISNALEISS 176 Query: 320 ---------------------RKNLLRTHTTSASARALYRLAQKKPFTPVKYFSIDRVFR 358 K LR+H TS + L KKP P K FSIDR FR Sbjct: 177 EMGLKILEDVFPEFKDLTAVSSKLTLRSHMTSGWFLTVSDLMNKKPL-PFKLFSIDRCFR 235 Query: 359 NET-LDATHLAEFHQIEGVVADHGLTLGHLMGVLREFFTKLGITQLRFKPA------YNP 411 E D +HL +H +A G+ + + ++ G T +F P Y P Sbjct: 236 REQKEDKSHLMTYHSASCAIAGEGVDINDGKAIAEGLLSQFGFTNFKFIPDEKKSKYYTP 295 Query: 412 YTEPSMEVFSYHQGLKKWVEVGNSGVFRPEMLLPMGLPENVSVIAWGLSLERPTMIKYGI 471 T+ EV++YH LK+W+EV GV+ P L G+ +V V+ GL +ER MI Sbjct: 296 ETQ--TEVYAYHPKLKEWLEVATFGVYSPVALSKYGI--DVPVMNLGLGVERLAMISGNF 351 Query: 472 NNIRE-----LVGHKVNLQMVYDSPLCRLDAEP 499 ++RE HK+N + V + + +LD P Sbjct: 352 ADVREMVYPQFYEHKLNDRNV--ASMVKLDKVP 382 >2DU7-A nrPDB Length = 549 Score = 214 bits (545), Expect = 7e-56, Method: Composition-based stats. Identities = 81/332 (24%), Positives = 133/332 (40%), Gaps = 58/332 (17%) Query: 219 PDSGHLHPLLKVRSQFRQIFLEMGFTEMPTDNFIESS--FWNF--------DALFQPQQH 268 P G HP+++ + RQ +L MGF EM ++ + F D F Sbjct: 51 PVYGKPHPVMETIERLRQAYLRMGFEEMINPVIVDEMEIYKQFGPEAMAVLDRCFYLAGL 110 Query: 269 PARDQH----------------DT-----------FFLRDPAEALQLPMDYVQRVKRTHS 301 P D D + + + L + + + ++ Sbjct: 111 PRPDVGLGNEKVEIIKNLGIDIDEEKKERLREVLHLYKKGAIDGDDLVFEIAKALNVSNE 170 Query: 302 QGGYGSQGYKYNWK--LDEARKNLLRTHTTSASARALYRLAQKKPFTPVKYFSIDRVFRN 359 G + +K E+ LR+H TS L L +K+ P+K FSIDR FR Sbjct: 171 MGLKVLETAFPEFKDLKPESTTLTLRSHMTSGWFITLSSLIKKRKL-PLKLFSIDRCFRR 229 Query: 360 ETL-DATHLAEFHQIEGVVADHGLTLGHLMGVLREFFTKLGITQLRFKPA------YNPY 412 E D +HL +H VV +++ V + G T+ +FKP Y P Sbjct: 230 EQREDRSHLMSYHSASCVVVGEDVSVDDGKVVAEGLLAQFGFTKFKFKPDEKKSKYYTPE 289 Query: 413 TEPSMEVFSYHQGLKKWVEVGNSGVFRPEMLLPMGLPENVSVIAWGLSLERPTMIKYGIN 472 T+ EV++YH L +W+EV GV+ P L + +V V+ GL +ER MI YG Sbjct: 290 TQ--TEVYAYHPKLGEWIEVATFGVYSPIALAKYNI--DVPVMNLGLGVERLAMIIYGYE 345 Query: 473 NIRE-----LVGHKVNLQMVYDSPLCRLDAEP 499 ++R ++++ + + + + R+D P Sbjct: 346 DVRAMVYPQFYEYRLSDRDI--AGMIRVDKVP 375 >3TUP-A nrPDB Length = 415 Score = 210 bits (534), Expect = 1e-54, Method: Composition-based stats. Identities = 69/306 (22%), Positives = 114/306 (37%), Gaps = 96/306 (31%) Query: 225 HPLLKVRSQFRQIFLEMGFTEMPTDNF--------IESSFWNFDALFQPQQHPARDQHDT 276 HPL ++ + ++ F + T F + +++ NFD+L P HP+R + D Sbjct: 48 HPLWLIKERVKEHFYKQYVGRFGTPLFSVYDNLSPVVTTWQNFDSLLIPADHPSRKKGDN 107 Query: 277 FFLRDPAEALQLPMDYVQRVKRTHSQGGYGSQGYKYNWKLDEARKNLLRTHTTSASARAL 336 ++L RTH +LR HT++ L Sbjct: 108 YYL-----------------NRTH----------------------MLRAHTSAHQWDLL 128 Query: 337 YRLAQKKPFTPVKYFSIDRVFRNETLDATHLAEFHQIEGV--VADHGLTLG--------- 385 + + + V+R + +D+ H FHQ+E V + H L G Sbjct: 129 HAGLDA-------FLVVGDVYRRDQIDSQHYPIFHQLEAVRLFSKHELFAGIKDGESLQL 181 Query: 386 -------------HLMGVLR--EFFTKLGITQL-----------RFKPAYNPYTEPSMEV 419 H M ++ EF K +T+L R+ Y P+T PS E+ Sbjct: 182 FEQSSRSAHKQETHTMEAVKLVEFDLKQTLTRLMAHLFGDELEIRWVDCYFPFTHPSFEM 241 Query: 420 -FSYHQGLKKWVEVGNSGVFRPEMLLPMGLPENVSVIAWGLSLERPTMIKYGINNIRELV 478 ++H +W+EV GV +++ G + + A+GL LER MI Y I +IR Sbjct: 242 EINFH---GEWLEVLGCGVMEQQLVNSAGAQDRI-GWAFGLGLERLAMILYDIPDIRLFW 297 Query: 479 GHKVNL 484 Sbjct: 298 CEDERF 303 >2DU4-A nrPDB Length = 534 Score = 200 bits (507), Expect = 2e-51, Method: Composition-based stats. Identities = 73/335 (21%), Positives = 124/335 (37%), Gaps = 61/335 (18%) Query: 222 GHLHPLLKVRSQFRQIFLEMGFTEMPTDNFIESSF----WNFDAL----------FQPQQ 267 G HPL + R+ +L +GF+E+ +E + +AL P+ Sbjct: 44 GKEHPLFATIQRLREAYLSIGFSEVVNPLIVEDVHVKKQFGREALAVLDRCFYLATLPKP 103 Query: 268 H-------------------PARDQHDTFFLRDPAEALQLPMDYVQRVKRTHSQGGYGSQ 308 + ++ + F E + Y+ Sbjct: 104 NVGISAEKIRQIEAITKREVDSKPLQEIFHRYKKGEIDGDDLSYLIAEVLDVDDITAVKI 163 Query: 309 GYKYNWKLDE----ARKNLLRTHTTSASARALYRLAQKKPFTPVKYFSIDRVFRNET-LD 363 + + E + LR+H T+ L +A K P P+K FSIDR FR E D Sbjct: 164 LDEVFPEFKELKPISSTLTLRSHMTTGWFITLSHIADKLPL-PIKLFSIDRCFRREQGED 222 Query: 364 ATHLAEFHQIEGVVADHGLTLGHLMGVLREFFTKLGITQLRFKPA------YNPYTEPSM 417 AT L + V+ D L++ V + G RF+ Y P T+ Sbjct: 223 ATRLYTYFSASCVLVDEELSVDDGKAVAEALLRQFGFENFRFRKDEKRSKYYIPDTQ--T 280 Query: 418 EVFSYHQGL--------KKWVEVGNSGVFRPEMLLPMGLPENVSVIAWGLSLERPTMIKY 469 EVF++H L W+E+ G++ P L +P V+ GL +ER MI Y Sbjct: 281 EVFAFHPKLVGSSTKYSDGWIEIATFGIYSPTALAEYDIP--YPVMNLGLGVERLAMILY 338 Query: 470 GINNIRELV----GHKVNLQMVYDSPLCRLDAEPR 500 G +++R++V ++ L + + ++ P+ Sbjct: 339 GYDDVRKMVYPQIHGEIKLSDLDIAREIKVKEVPQ 373 >1PYS-B nrPDB Length = 785 Score = 50.6 bits (119), Expect = 1e-06, Method: Composition-based stats. Identities = 37/139 (26%), Positives = 50/139 (35%), Gaps = 23/139 (16%) Query: 321 KNLLRTHTTSASARALYRLAQKKPFTPVKYFSIDRVFRNETLDATHLAEFHQIEGVVADH 380 K LRTH R L F + RVFR + THLA G++ Sbjct: 541 KAALRTHLFPGLVRVLKENLDLDRPERALLFEVGRVFR--EREETHLA------GLLFGE 592 Query: 381 GLTLG----------HLMGVLREFFTKLGITQLRFKPAYNPYTEPSMEVFSYHQGLKKWV 430 G+ L L G L F +LG+ R + P+ P + L + Sbjct: 593 GVGLPWAKERLSGYFLLKGYLEALFARLGLA-FRVEAQAFPFLHPG----VSGRVLVEGE 647 Query: 431 EVGNSGVFRPEMLLPMGLP 449 EVG G PE+ + LP Sbjct: 648 EVGFLGALHPEIAQELELP 666 >2ZNJ-A nrPDB Length = 308 Score = 50.2 bits (118), Expect = 2e-06, Method: Composition-based stats. Identities = 34/146 (23%), Positives = 56/146 (38%), Gaps = 12/146 (8%) Query: 335 ALYRLAQKKPFTPVKYFSIDRVFRNETLDATHLAEFHQIEGVVADHGLTLGH--LMGVLR 392 L+R ++ P++ F I +R E+ A HL EF + L H L + R Sbjct: 157 TLWRELERLWDKPIRIFEIGTCYRKESQGAQHLNEFTMLNLTELGTPLEERHQRLEDMAR 216 Query: 393 EFFTKLGITQLRFKPAYNPYTEPSMEVFSYHQGLKKWVEVGNSGVFRPEML-LPMGLPEN 451 GI + TE S+ +K +E+ SG P L + + Sbjct: 217 WVLEAAGIREFELV------TESSVVYGDTVDVMKGDLELA-SGAMGPHFLDEKWEIFD- 268 Query: 452 VSVIAWGLSLERPTMIKYGINNIREL 477 + G LER MI+ G +++ + Sbjct: 269 -PWVGLGFGLERLLMIREGTQHVQSM 293 >3VQX-A nrPDB Length = 291 Score = 49.4 bits (116), Expect = 3e-06, Method: Composition-based stats. Identities = 38/153 (24%), Positives = 58/153 (37%), Gaps = 12/153 (7%) Query: 324 LRTHTTSASARALYRLAQKKPFTPVKYFSIDRVFRNETLDATHLAEFHQIEGVVADHGLT 383 LR L +L + P P+K F I +R E+ HL EF + G T Sbjct: 134 LRPMLAPNLYNYLRKLDRALP-DPIKIFEIGPCYRKESDGKEHLEEFTMLNFCQMGSGCT 192 Query: 384 LGHLMGVLREFFTKLGITQLRFKPAYNPYTEPSMEVFSYHQGLKKWVEVGNSGVFRPEML 443 +L ++ +F LG + FK + + H L+ +S V P L Sbjct: 193 RENLESIITDFLNHLG---IDFKIVGDSCMVYGDTLDVMHGDLE-----LSSAVVGPIPL 244 Query: 444 -LPMGLPENVSVIAWGLSLERPTMIKYGINNIR 475 G+ + I G LER +K+ NI+ Sbjct: 245 DREWGIDK--PWIGAGFGLERLLKVKHDFKNIK 275 >5HGQ-A nrPDB Length = 524 Score = 37.5 bits (85), Expect = 0.015, Method: Composition-based stats. Identities = 16/50 (32%), Positives = 24/50 (48%), Gaps = 2/50 (4%) Query: 349 KYFSIDRVFRNETLDATHLAEFHQIEGVVADHGLTLGHLMGVLREFFTKL 398 + + I RVFRNE +D TH EF E +A LM + + ++ Sbjct: 248 RVYEIGRVFRNEGIDQTHNPEFTSCEFYMAYAD--YEDLMKITEDMLARM 295 Score = 33.2 bits (74), Expect = 0.27, Method: Composition-based stats. Identities = 12/34 (35%), Positives = 18/34 (52%), Gaps = 3/34 (8%) Query: 445 PMGLPENVSVIAWGLSLERPTMIKYGINNIRELV 478 GLP WG+ ++R MI NNI+E++ Sbjct: 473 EYGLP---PTAGWGMGIDRLAMILTDSNNIKEVL 503 >4YCV-A nrPDB Length = 516 Score = 37.1 bits (84), Expect = 0.019, Method: Composition-based stats. Identities = 27/100 (27%), Positives = 40/100 (40%), Gaps = 12/100 (12%) Query: 326 THTTSASARALYRLAQKKPFTPV------KYFSIDRVFRNETLDATHLAEFHQIEGVVAD 379 TH R+A + P + K + I +VFRNE +D TH EF E Sbjct: 217 THHNDLDLDLYLRIATELPLKMLIVGGIDKVYEIGKVFRNEGIDNTHNPEFTSCE--FYW 274 Query: 380 HGLTLGHLMGVLREFFTKLGITQL-RFKPAYN---PYTEP 415 L+ +FF++L +K +YN P +P Sbjct: 275 AYADYNDLIKWSEDFFSQLVYHLFGTYKISYNKDGPENQP 314 >2GZM-A nrPDB Length = 267 Score = 36.7 bits (83), Expect = 0.027, Method: Composition-based stats. Identities = 25/86 (29%), Positives = 44/86 (51%), Gaps = 18/86 (20%) Query: 30 LGMEHQAVVGAVKSLQALGEVIEAELRSTKHWELTAEGEEIAREGS---HEARVFRSIPP 86 LG H ++G V Q +G+ ++ L + G+E ARE S + +++ Sbjct: 182 LGCTHYPILGPVIK-QVMGDKVQ----------LISSGDETAREVSTILYHSKMLN---- 226 Query: 87 EGLAQSELMRLPSGKVGFSKAMSNKW 112 EG QS+ + L +GK+G K +++KW Sbjct: 227 EGEEQSDHLFLTTGKIGLFKEIASKW 252 >5EP0-A nrPDB Length = 396 Score = 35.6 bits (80), Expect = 0.048, Method: Composition-based stats. Identities = 40/168 (23%), Positives = 73/168 (43%), Gaps = 16/168 (9%) Query: 12 RRLEASDGGLDSAELAAELGMEHQAVVGAVKSLQALGEVIEAELRSTKHWELTAE---GE 68 + L+A S + G ++Q +G +QA+ VIE+ S +T E G+ Sbjct: 118 KALKAESKSNTSTQSKQSDGAQYQGFIGNSLPMQAVYRVIESAASSKATVFITGESGTGK 177 Query: 69 EIAREGSHEARVFRSIP---------PEGLAQSELMRLPSGKVGFSKAMSNKWIRVDKSA 119 E+ E H A P P+ L +SEL G F+ A + + V+ A Sbjct: 178 EVCAEAIHAASPRHDKPFIALNCAAIPKDLIESELFGHVKG--AFTGASTERQGAVEM-A 234 Query: 120 ADGPRVFRVVDSMEDEVQRR-LQLVRGGQAEKLGEKERSELRKRKLLA 166 +G + + M+ ++Q + L+ ++ G +K+G + S + R + A Sbjct: 235 HNGTLMLDELCEMDLDLQSKLLRFIQTGTYQKVGSSKMSSVDVRFVCA 282 >6JP2-A nrPDB Length = 278 Score = 35.6 bits (80), Expect = 0.050, Method: Composition-based stats. Identities = 49/262 (18%), Positives = 78/262 (29%), Gaps = 63/262 (24%) Query: 221 SGHLHPLLKVRSQFRQIFLEMGFTEMPTDNFIESSFWNFDALFQPQQHPARDQHDTFFLR 280 + H L ++ + + GF E+ T FI + + P Q F++ Sbjct: 60 NPSRHGLTQLMNDIADALVAEGFIEVRTPIFISKD--ALARMTITEDKPLFKQ--VFWID 115 Query: 281 DPAEALQLPMDYVQRVKRTHSQGGYGSQGYKYNWKLDEARKNLLRTHTTSASARALYRLA 340 + + + V R LR HT Sbjct: 116 EKRALRPMLAPNLYSVMRD------------------------LRDHTD----------- 140 Query: 341 QKKPFTPVKYFSIDRVFRNETLDATHLAEFHQIEGVVAD-HGLTLGHLMGVLREFFTKLG 399 PVK F + FR E+ HL EF + V G L + G Sbjct: 141 -----GPVKIFEMGSCFRKESHSGMHLEEFTMLNLVDMGPRGDATEVLKNYISVVMKAAG 195 Query: 400 ITQLRFKPAYNPYTEPSMEVFSYHQGLKKWVEVGN----SGVFRPEMLLPM-GLPENVSV 454 + P Y+ E E Y + + VE+ S P L + E S Sbjct: 196 L------PDYDLVQE---ESDVYKETID--VEINGQEVCSAAVGPHYLDAAHDVHEPWSG 244 Query: 455 IAWGLSLERPTMIKYGINNIRE 476 +GL ER I+ + +++ Sbjct: 245 AGFGL--ERLLTIREKYSTVKK 264 >6NRZ-A nrPDB Length = 534 Score = 35.2 bits (79), Expect = 0.063, Method: Composition-based stats. Identities = 30/141 (21%), Positives = 48/141 (34%), Gaps = 8/141 (5%) Query: 270 ARDQHDTFFLRDPAEALQLPMDYVQRVKRTHSQGGYGSQGYKYNWKLDEARKNLLRTHTT 329 + D TF R L Q + G + L H Sbjct: 193 SEDVRKTFLTRSRILKLIREYMDQQSFLEVETPILQTVYGGAEATPFVTTLQAL---HAE 249 Query: 330 SASARALYRLAQKKPFTPV-KYFSIDRVFRNETLDATHLAEFHQIEGVVA--DHGLTLGH 386 +L +K + + + I +VFRNE +D TH EF IE A D+ + Sbjct: 250 MFLRISLEIALKKLLVGGMSRVYEIGKVFRNEGIDRTHNPEFTMIEAYAAYWDYNDVMKC 309 Query: 387 LMGVLREFFTKL--GITQLRF 405 + ++ L G TQ+++ Sbjct: 310 VENLVEYIVRALNNGETQVQY 330 Score = 31.7 bits (70), Expect = 0.84, Method: Composition-based stats. Identities = 19/80 (23%), Positives = 32/80 (40%), Gaps = 22/80 (27%) Query: 396 TKLGITQLRFKPAYNPYTEPSMEVFSYHQGLKKWVEVGNSGVFRPEMLLPMGLPENVSVI 455 KL Q+R K A NP +E YH ++++E G+ P Sbjct: 461 RKLLEEQMR-KKALNPDSE-------YHPIDEEFLEALCQGM--P------------PAG 498 Query: 456 AWGLSLERPTMIKYGINNIR 475 +G+ ++R M+ +IR Sbjct: 499 GFGIGIDRLVMMLTDAASIR 518 >6AQH-A nrPDB Length = 508 Score = 35.2 bits (79), Expect = 0.072, Method: Composition-based stats. Identities = 19/64 (29%), Positives = 28/64 (43%), Gaps = 2/64 (3%) Query: 349 KYFSIDRVFRNETLDATHLAEFHQIEGVVADHGLTLGHLMGVLREFFTKLGITQLRFKPA 408 + F ++RVFRNE D+TH EF +E A T V RE ++ + + Sbjct: 257 RVFELNRVFRNEGADSTHSPEFVMLETYQAYG--TYDDSAVVTRELIQEVADEAIGTRQV 314 Query: 409 YNPY 412 P Sbjct: 315 PLPD 318 >1ADJ-A nrPDB Length = 421 Score = 34.8 bits (78), Expect = 0.083, Method: Composition-based stats. Identities = 25/105 (23%), Positives = 44/105 (41%), Gaps = 2/105 (1%) Query: 320 RKNLLRTHTTSASARALYRLAQKKPFTPVKYFSIDRVFRNETLDATHLAEFHQI--EGVV 377 R LR T+A RA K PV+ + +FR E +FHQ+ E + Sbjct: 74 RSLTLRPEGTAAMVRAYLEHGMKVWPQPVRLWMAGPMFRAERPQKGRYRQFHQVNYEALG 133 Query: 378 ADHGLTLGHLMGVLREFFTKLGITQLRFKPAYNPYTEPSMEVFSY 422 +++ + + +L E +LG+ +L+ K + E +Y Sbjct: 134 SENPILDAEAVVLLYECLKELGLRRLKVKLSSVGDPEDRARYNAY 178 >4UP8-A nrPDB Length = 777 Score = 34.8 bits (78), Expect = 0.092, Method: Composition-based stats. Identities = 15/50 (30%), Positives = 23/50 (46%), Gaps = 2/50 (4%) Query: 349 KYFSIDRVFRNETLDATHLAEFHQIEGVVADHGLTLGHLMGVLREFFTKL 398 + + I R+FRNE +D TH EF E +A +M + E + Sbjct: 250 RVYEIGRLFRNEGIDQTHNPEFTTCEFYMAYAD--YNDIMKMTEELLGNM 297 Score = 32.5 bits (72), Expect = 0.51, Method: Composition-based stats. Identities = 8/22 (36%), Positives = 16/22 (72%) Query: 457 WGLSLERPTMIKYGINNIRELV 478 WGL ++R M+ ++NI+E++ Sbjct: 541 WGLGIDRLAMLLADVDNIKEVI 562 >6AQG-A nrPDB Length = 506 Score = 34.4 bits (77), Expect = 0.11, Method: Composition-based stats. Identities = 17/64 (26%), Positives = 27/64 (42%), Gaps = 2/64 (3%) Query: 349 KYFSIDRVFRNETLDATHLAEFHQIEGVVADHGLTLGHLMGVLREFFTKLGITQLRFKPA 408 + F ++RVFRNE D+TH EF +E T + RE ++ + + Sbjct: 254 RVFELNRVFRNEGSDSTHSPEFSMLE--TYQTYGTYDDSALITRELIQEVADEAIGTRQL 311 Query: 409 YNPY 412 P Sbjct: 312 SMPD 315 >1QE0-A nrPDB Length = 420 Score = 34.0 bits (76), Expect = 0.15, Method: Composition-based stats. Identities = 25/134 (18%), Positives = 48/134 (35%), Gaps = 5/134 (3%) Query: 276 TFFLRDPAEALQLPMDYVQRVKRTHSQGGYGSQGYKYNWKLDEARKNLLRTHTTSASARA 335 TF+ + S + Y + K D R LR T+A R+ Sbjct: 31 TFYNYKEIRTPIFESTDLFARGVGDSTDVVQKEMYTFKDKGD--RSITLRPEGTAAVVRS 88 Query: 336 -LYRLAQKKPFTPVKYFSIDRVFRNETLDATHLAEFHQ--IEGVVADHGLTLGHLMGVLR 392 + Q P P+K + +FR E +F+Q +E + A++ ++ ++ Sbjct: 89 YIEHKMQGNPNQPIKLYYNGPMFRYERKQKGRYRQFNQFGVEAIGAENPSVDAEVLAMVM 148 Query: 393 EFFTKLGITQLRFK 406 + G+ L+ Sbjct: 149 HIYQSFGLKHLKLV 162 >4WJ3-M nrPDB Length = 599 Score = 32.9 bits (73), Expect = 0.36, Method: Composition-based stats. Identities = 29/121 (23%), Positives = 49/121 (40%), Gaps = 8/121 (6%) Query: 319 ARKNLLRTHTTSASARALYRLAQKKPFTPV-----KYFSIDRVFRNETLDATHLAEFHQ- 372 AR L+ + T AL + Q + +Y+ I + FR+E L A EF Q Sbjct: 184 ARDYLVPSRTYPGHFFALPQSPQLFKQLLMVAGFDRYYQIAKCFRDEDLRADRQPEFTQI 243 Query: 373 -IEGVVADHGLTLGHLMGVLREFFTKLGITQLRFKPAYNPYTEPSMEVFSYHQGLKKWVE 431 IE D +G ++R+ F ++ + P + P+ E S L+ +E Sbjct: 244 DIETSFLDESDIIGITEKMVRQLFKEVLDVEFDEFP-HMPFEEAMRRYGSDKPDLRIPLE 302 Query: 432 V 432 + Sbjct: 303 L 303 >5ELO-A nrPDB Length = 535 Score = 32.5 bits (72), Expect = 0.49, Method: Composition-based stats. Identities = 17/50 (34%), Positives = 24/50 (48%), Gaps = 2/50 (4%) Query: 349 KYFSIDRVFRNETLDATHLAEFHQIEGVVADHGLTLGHLMGVLREFFTKL 398 K + I + FRNE +D TH EF +E +A LM + E + L Sbjct: 262 KVYEIGKNFRNEGIDLTHNPEFTAMEFYMAYADYY--DLMDLTEELISGL 309 >1XHC-A nrPDB Length = 367 Score = 32.1 bits (71), Expect = 0.53, Method: Composition-based stats. Identities = 16/95 (16%), Positives = 33/95 (34%), Gaps = 1/95 (1%) Query: 338 RLAQKKPFTPVKYFSIDRVFRNETLDATHLAEFHQIEGVVADHGLTLGHLMGVLREFFTK 397 LA++ + ID FR D + + + G++A VL + Sbjct: 237 DLARRSGIHTGRGILIDDNFRTSAKDVYAIGDCAEYSGIIAGTAKAAMEQARVLADILKG 296 Query: 398 LGIT-QLRFKPAYNPYTEPSMEVFSYHQGLKKWVE 431 +F+ + + + + +G KW+E Sbjct: 297 EPRRYNFKFRSTVFKFGKLQIAIIGNTKGEGKWIE 331 >1W0O-A nrPDB Length = 781 Score = 32.1 bits (71), Expect = 0.54, Method: Composition-based stats. Identities = 44/272 (16%), Positives = 91/272 (33%), Gaps = 55/272 (20%) Query: 169 TLKTYWVSKGSAFSTSISKQETELSPEMISSGSWRDRPFKPYNFLAHG---VLP-----D 220 +L T ++ S+F ++ + LS MI+ N+ A+G VLP Sbjct: 80 SLSTNQHAQASSFGWRMTTEMKVLSGGMIT------------NYYANGTQRVLPIISLDS 127 Query: 221 SGHLHPLLKVRSQFRQIFLEMGFTEMPTDNFIESSFWNFDALFQPQQHPARDQH-DTFFL 279 SG+L + + G T + T + + F+ +F P +P+ + D + Sbjct: 128 SGNL---------VVEFEGQTGRTVLATGT-AATEYHKFELVFLPGSNPSASFYFDGKLI 177 Query: 280 RD---PAEALQLPMDYVQRVKRTHSQGGYGSQGYKYNWKL----DEARKNLLRTHTTSAS 332 RD P + Q + + T Y ++ + + +++ + T Sbjct: 178 RDNIQPTASKQNMIVWGNGSSNTDGVAAYRDIKFEIQGDVIFRGPDRIPSIVASSVTPG- 236 Query: 333 ARALYRLAQKKPFTPVKYFSIDRVFRNETLDATHLAEFHQIEGVVADHGLTLGHLMGVLR 392 + + P + + + + D G+ D L L + V Sbjct: 237 VVTAFAEKRVGGGDPGALSNTNDIITRTSRDG----------GITWDTELNLTEQINVSD 286 Query: 393 EFFTKLGITQLRFKPAYNPYTEPSMEVFSYHQ 424 EF +P Y+P + + ++ Sbjct: 287 EFDFSDP------RPIYDPSSNTVLVSYARWP 312 >3I7F-A nrPDB Length = 548 Score = 31.7 bits (70), Expect = 0.84, Method: Composition-based stats. Identities = 13/42 (30%), Positives = 16/42 (38%), Gaps = 3/42 (7%) Query: 438 FRPEMLLPMGLPENVSVI---AWGLSLERPTMIKYGINNIRE 476 P L G+ LER TM+ GI NIR+ Sbjct: 494 VDPATLKDYIESFRFGSWPHAGCGIGLERITMLYLGIPNIRK 535 >6ILH-A nrPDB Length = 521 Score = 31.3 bits (69), Expect = 0.90, Method: Composition-based stats. Identities = 12/26 (46%), Positives = 15/26 (57%) Query: 349 KYFSIDRVFRNETLDATHLAEFHQIE 374 + + I R FRNE +D TH EF E Sbjct: 246 RVYEIGRQFRNEGIDLTHNPEFTTCE 271 Score = 30.2 bits (66), Expect = 2.1, Method: Composition-based stats. Identities = 11/34 (32%), Positives = 17/34 (50%), Gaps = 3/34 (8%) Query: 445 PMGLPENVSVIAWGLSLERPTMIKYGINNIRELV 478 GLP WG+ ++R M NNI+E++ Sbjct: 470 EYGLP---PTAGWGMGIDRVAMFLTDSNNIKEVL 500 >6CHD-A nrPDB Length = 597 Score = 31.3 bits (69), Expect = 0.90, Method: Composition-based stats. Identities = 12/26 (46%), Positives = 15/26 (57%) Query: 349 KYFSIDRVFRNETLDATHLAEFHQIE 374 + + I R FRNE +D TH EF E Sbjct: 314 RVYEIGRQFRNEGIDLTHNPEFTTCE 339 Score = 30.2 bits (66), Expect = 2.1, Method: Composition-based stats. Identities = 11/34 (32%), Positives = 17/34 (50%), Gaps = 3/34 (8%) Query: 445 PMGLPENVSVIAWGLSLERPTMIKYGINNIRELV 478 GLP WG+ ++R M NNI+E++ Sbjct: 538 EYGLP---PTAGWGMGIDRVAMFLTDSNNIKEVL 568 >3OD1-A nrPDB Length = 400 Score = 30.9 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 14/84 (16%), Positives = 33/84 (39%), Gaps = 3/84 (3%) Query: 323 LLRTHTTSASARALYRLAQKKPFTPVKYFSIDRVFRNETLDATHLAEFHQIEGVVADHGL 382 +LR T+ AR + + + + P++ V+R + + AEF Q+ + G Sbjct: 80 VLRPDMTAPIARLVASSLKDRAY-PLRLAYQSNVYRAQQNEGGKPAEFEQLGVELIGDGT 138 Query: 383 TLGHLMGVLREF--FTKLGITQLR 404 + + G+++ + Sbjct: 139 ASADGEVIALMIAALKRAGLSEFK 162 >1UG3-A nrPDB Length = 339 Score = 30.9 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 38/136 (27%), Positives = 59/136 (43%), Gaps = 8/136 (5%) Query: 18 DGGLDSAELAAELGMEHQAVVGAVKSLQALGEVIEAE-LRSTKHWELTAEGEEIAREGSH 76 + GL E E G + A V K LGE EA R+ EL + E++ +EGS Sbjct: 166 EAGLSWKEFLPE-GQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS 224 Query: 77 EARVF----RSIPPEGLAQSELMRLPSGKVGFSKAMSNKWIRVDKSAADGPRVFRVVDSM 132 RVF ++ + + + L+R V +S + +RVD + R + + Sbjct: 225 NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKA-RAKLLQKYL 283 Query: 133 EDEVQRRLQLVRGGQA 148 DE Q+ LQ + QA Sbjct: 284 CDE-QKELQALYALQA 298 >6NUD-J nrPDB Length = 758 Score = 30.5 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 31/204 (15%), Positives = 60/204 (29%), Gaps = 28/204 (13%) Query: 274 HDTFFLRDPAEALQLPMDY---VQRVKRTHSQGGYGSQGYKYNWKLDEARKNLLRTHTTS 330 +F +D L P Y Q+ R S+ Y+ L+ K+ R Sbjct: 343 WGSFAAKDIMSELNSPESYRQIYQKASRMISEKKISRYDYRTLMLLNRGGKSSERECEIC 402 Query: 331 ASARALYRLAQKKPFTPVKYFSIDRVFRNETLDATHLAEFHQIEGVVADHGLTLGHLMGV 390 S L +K + ++ A + EG+ L GV Sbjct: 403 HSVENLVSYHDQKVCDICRGL-----YQFSKEIAHDHFIITENEGLPIGPN---ACLKGV 454 Query: 391 LREFFTKLGITQLRFKPAYNPYTEPSMEVFSYHQGLKKWVEVGNSGVFRPEMLLPMGLPE 450 E ++ +++ K Y T + VF + L Sbjct: 455 AFEKLSQESFSRVYVKNDYKAGTIKATHVFVGDYQCDE---------IHKYAALSKNED- 504 Query: 451 NVSVIAWGLSLERPTMIKYGINNI 474 GL ++R +++ ++++ Sbjct: 505 -------GLGIKRLAVVRLDVDDL 521 >3A74-A nrPDB Length = 493 Score = 30.5 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 12/26 (46%), Positives = 15/26 (57%) Query: 349 KYFSIDRVFRNETLDATHLAEFHQIE 374 K + I RVFRNE + H EF +E Sbjct: 244 KVYEIGRVFRNEGISTRHNPEFTMLE 269 Score = 28.2 bits (61), Expect = 8.9, Method: Composition-based stats. Identities = 7/31 (22%), Positives = 13/31 (41%), Gaps = 3/31 (9%) Query: 445 PMGLPENVSVIAWGLSLERPTMIKYGINNIR 475 G+P G+ ++R M+ +IR Sbjct: 455 EYGMP---PTGGLGIGVDRLVMLLTNSPSIR 482 >2EXX-A nrPDB Length = 306 Score = 30.2 bits (66), Expect = 2.0, Method: Composition-based stats. Identities = 24/119 (20%), Positives = 42/119 (35%), Gaps = 16/119 (13%) Query: 366 HLAEFHQIEGV--VADHGLTLGH--LMGVLREFFTKLG--ITQLRFKPAYN--------P 411 H + +E + + L H G + E+F +G +T +R P Y P Sbjct: 114 HYVVYSGLENIKKLTAGRLAAAHFDGKGEVEEYFRDIGVPMTSVRL-PCYFENLLSHFLP 172 Query: 412 YTEPSMEVFSYH-QGLKKWVEVGNSGVFRPEMLLPMGLPENVSVIAWGLSLERPTMIKY 469 P + + ++ + P +L + +PE GLS R T +Y Sbjct: 173 QKAPDGKSYLLSLPTGDVPMDGMSVSDLGPVVLSLLKMPEKYVGQNIGLSTCRHTAEEY 231 >2KY4-A nrPDB Length = 149 Score = 30.2 bits (66), Expect = 2.3, Method: Composition-based stats. Identities = 13/49 (26%), Positives = 20/49 (40%), Gaps = 2/49 (4%) Query: 377 VADHGLTLGHLMGVLREFFTKLGITQLRFKPAYNPYTEPSMEVFSYHQG 425 + LG+ ++EF LG + L K Y PY P+ +V Sbjct: 41 FSGWESKLGNGEITVKEFIEGLGYSNLYLKEFYTPY--PNTKVIELGTK 87 >2KK6-A nrPDB Length = 116 Score = 30.2 bits (66), Expect = 2.3, Method: Composition-based stats. Identities = 11/86 (12%), Positives = 23/86 (26%) Query: 250 NFIESSFWNFDALFQPQQHPARDQHDTFFLRDPAEALQLPMDYVQRVKRTHSQGGYGSQG 309 E +++ Q + Q D + + + +R H Y Sbjct: 13 PLAEQDWYHGAIPRIEAQELLKKQGDFLVRESHGKPGEYVLSVYSDGQRRHFIIQYVDNM 72 Query: 310 YKYNWKLDEARKNLLRTHTTSASARA 335 Y++ L+ H T+ Sbjct: 73 YRFEGTGFSNIPQLIDHHYTTKQVIT 98 >3P8T-A nrPDB Length = 294 Score = 30.2 bits (66), Expect = 2.4, Method: Composition-based stats. Identities = 20/124 (16%), Positives = 42/124 (33%), Gaps = 4/124 (3%) Query: 330 SASARALYRLAQKKPFTPVKYFSID-RVFRNETLDATHLAEFHQIEGVVADHGLTLGHLM 388 + S +LA + S + R+ D H EF Q++ + G + +M Sbjct: 73 THSMILHKQLAIAMGLEKIFVLSPNIRLESRRKDDGRHSYEFTQLDFEI--EGAKMKDVM 130 Query: 389 GVLREFFTKLGITQLRFKPAYNPYTEPSMEVFSYHQGLKKWVEVGNSGVFRPEMLLPMGL 448 ++ E L + P +V+ Y L+++ + + E + + Sbjct: 131 RLIEELIYGLFRKAEEWTGREFPRAR-HFKVYDYKDILEEFGSDEKASMEMEEPFWIVNI 189 Query: 449 PENV 452 P Sbjct: 190 PREF 193 >6NIY-R nrPDB Length = 474 Score = 29.8 bits (65), Expect = 3.2, Method: Composition-based stats. Identities = 10/33 (30%), Positives = 15/33 (45%) Query: 399 GITQLRFKPAYNPYTEPSMEVFSYHQGLKKWVE 431 G+ +F P Y P +PS +V Y W + Sbjct: 88 GVLSYQFCPDYFPDFDPSEKVTKYCDEKGVWFK 120 >5II0-A nrPDB Length = 122 Score = 29.8 bits (65), Expect = 3.2, Method: Composition-based stats. Identities = 10/33 (30%), Positives = 15/33 (45%) Query: 399 GITQLRFKPAYNPYTEPSMEVFSYHQGLKKWVE 431 G+ +F P Y P +PS +V Y W + Sbjct: 66 GVLSYQFCPDYFPDFDPSEKVTKYCDEKGVWFK 98 >2H09-A nrPDB Length = 155 Score = 29.4 bits (64), Expect = 4.2, Method: Composition-based stats. Identities = 18/62 (29%), Positives = 31/62 (50%), Gaps = 3/62 (4%) Query: 19 GGLDSAELAAELGMEHQAVVGAVKSLQALGEVIEAELRSTKHWELTAEGEEIAREGSHEA 78 G ++AA LG+ V +K L +G + E+ + LTAEGE++A+E Sbjct: 53 GEARQVDMAARLGVSQPTVAKMLKRLATMGLI---EMIPWRGVFLTAEGEKLAQESRERH 109 Query: 79 RV 80 ++ Sbjct: 110 QI 111 >5W25-A nrPDB Length = 616 Score = 29.0 bits (63), Expect = 5.6, Method: Composition-based stats. Identities = 29/139 (20%), Positives = 47/139 (33%), Gaps = 11/139 (7%) Query: 349 KYFSIDRVFRNETLDATHLAEFHQI--EGVVADHGLTLGHLMGVLREFFTKLGITQLRFK 406 +Y+ I R +R+E A EF Q+ E D + VL E + +G Sbjct: 232 RYYQIARCYRDEDFRADRQPEFTQLDMEMSFVDAEDIIAISEEVLTELWALIGYR----I 287 Query: 407 PAYNP---YTEPSMEVFSYHQGLKKWVEVGNS-GVFRPEMLLPMGLPENVSVIAWGLSLE 462 P P Y E + L+ +E+ F P +V+ G Sbjct: 288 PTPIPRIGYAEAMRRFGTDKPDLRFGLELVECTDFFSDTTFRVFQAPYVGAVVMPG-GAS 346 Query: 463 RPTMIKYGINNIRELVGHK 481 +P G + + GH+ Sbjct: 347 QPRRTLDGWQDWAKQRGHR 365 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.122 0.333 Lambda K H 0.267 0.0378 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 19,052,792 Number of Sequences: 36641 Number of extensions: 734735 Number of successful extensions: 2302 Number of sequences better than 10.0: 48 Number of HSP's better than 10.0 without gapping: 52 Number of HSP's successfully gapped in prelim test: 29 Number of HSP's that attempted gapping in prelim test: 2140 Number of HSP's gapped (non-prelim): 117 length of query: 508 length of database: 10,336,785 effective HSP length: 101 effective length of query: 407 effective length of database: 6,636,044 effective search space: 2700869908 effective search space used: 2700869908 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 61 (28.2 bits)