BLASTP 2.2.23 [Feb-03-2010]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Altschul, Stephen F.,
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= Q9XSM3
(730 letters)
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
36,641 sequences; 10,336,785 total letters
Searching..................................................done
Results from round 1
Score E
Sequences producing significant alignments: (bits) Value
6DMR-A nrPDB 1518 0.0
6BOA-A nrPDB 1069 0.0
6E2G-A nrPDB 1069 0.0
2RFA-A nrPDB 361 e-100
6BBJ-A nrPDB 267 1e-71
6C8G-A nrPDB 267 1e-71
5IRX-A nrPDB 233 2e-61
6DVZ-A nrPDB 230 2e-60
6MHW-A nrPDB 223 2e-58
5AN8-A nrPDB 196 4e-50
5HI9-A nrPDB 182 5e-46
6BO5-A nrPDB 182 5e-46
6OO7-A nrPDB 159 6e-39
2ETB-A nrPDB 109 5e-24
2NYJ-A nrPDB 103 2e-22
2F37-A nrPDB 100 2e-21
4DX2-A nrPDB 100 3e-21
3W9G-A nrPDB 100 3e-21
4N5Q-A nrPDB 95 1e-19
5OEO-C nrPDB 88 1e-17
5MIO-C nrPDB 74 2e-13
6MWQ-A nrPDB 70 2e-12
5H76-A nrPDB 64 2e-10
6FES-A nrPDB 63 4e-10
5AQA-A nrPDB 60 3e-09
5AQB-A nrPDB 59 6e-09
5AQ7-A nrPDB 59 9e-09
5AQ9-A nrPDB 53 6e-07
6AUN-A nrPDB 51 2e-06
4Z68-A nrPDB 50 4e-06
5CBO-A nrPDB 48 1e-05
5GP7-A nrPDB 45 1e-04
4OAU-C nrPDB 44 3e-04
6G1K-A nrPDB 43 4e-04
5Z96-A nrPDB 43 5e-04
3B7B-A nrPDB 42 0.001
4OT9-A nrPDB 41 0.002
6BY9-A nrPDB 39 0.008
5HKP-A nrPDB 39 0.008
4NIK-A nrPDB 39 0.009
1BLX-B nrPDB 38 0.015
4O1O-A nrPDB 38 0.015
3EU9-A nrPDB 38 0.016
5JHQ-A nrPDB 38 0.018
5ET1-A nrPDB 36 0.049
1WG0-A nrPDB 36 0.051
5DND-A nrPDB 35 0.14
2KXP-C nrPDB 35 0.15
6CUD-A nrPDB 35 0.17
2DWZ-A nrPDB 35 0.17
1BD8-A nrPDB 34 0.20
6BWF-A nrPDB 34 0.20
3ZKJ-A nrPDB 34 0.26
6CV9-A nrPDB 33 0.33
3EHQ-A nrPDB 33 0.34
3DEO-A nrPDB 33 0.52
3UI2-A nrPDB 33 0.61
5MKE-A nrPDB 32 0.91
5UQE-A nrPDB 32 0.93
1G3N-B nrPDB 32 1.1
5U0J-A nrPDB 32 1.2
1DCQ-A nrPDB 31 2.0
6BPQ-A nrPDB 31 2.3
6DU8-A nrPDB 31 2.4
3CO4-A nrPDB 30 2.6
6EMK-G nrPDB 30 2.7
5U0K-A nrPDB 30 2.8
4BSZ-B nrPDB 30 3.7
5UIL-A nrPDB 30 3.9
6D1W-A nrPDB 30 3.9
6AYG-A nrPDB 30 4.2
3T9K-A nrPDB 29 6.8
5T4D-A nrPDB 29 7.3
5D68-A nrPDB 29 7.4
>6DMR-A nrPDB
Length = 730
Score = 1518 bits (3931), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 730/730 (100%), Positives = 730/730 (100%)
Query: 1 MGACPPKAKGPWAQLQKLLISWPVGEQDWEQYRDRVNMLQQERIRDSPLLQAAKENDLRL 60
MGACPPKAKGPWAQLQKLLISWPVGEQDWEQYRDRVNMLQQERIRDSPLLQAAKENDLRL
Sbjct: 1 MGACPPKAKGPWAQLQKLLISWPVGEQDWEQYRDRVNMLQQERIRDSPLLQAAKENDLRL 60
Query: 61 LKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTA 120
LKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTA
Sbjct: 61 LKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTA 120
Query: 121 LHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVR 180
LHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVR
Sbjct: 121 LHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVR 180
Query: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQG 240
LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQG
Sbjct: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQG 240
Query: 241 LTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSWGEELSFLELVVSSK 300
LTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSWGEELSFLELVVSSK
Sbjct: 241 LTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSWGEELSFLELVVSSK 300
Query: 301 KREARQILEQTPVKELVSFKWKKYGRPYFCVLASLYILYMICFTTCCIYRPLKLRDDNRT 360
KREARQILEQTPVKELVSFKWKKYGRPYFCVLASLYILYMICFTTCCIYRPLKLRDDNRT
Sbjct: 301 KREARQILEQTPVKELVSFKWKKYGRPYFCVLASLYILYMICFTTCCIYRPLKLRDDNRT 360
Query: 361 DPRDITILQQKLLQEAYVTHQDNIRLVGELVTVTGAVIILLLEIPDIFRVGASRYFGQTI 420
DPRDITILQQKLLQEAYVTHQDNIRLVGELVTVTGAVIILLLEIPDIFRVGASRYFGQTI
Sbjct: 361 DPRDITILQQKLLQEAYVTHQDNIRLVGELVTVTGAVIILLLEIPDIFRVGASRYFGQTI 420
Query: 421 LGGPFHVIIITYASLVLLTMVMRLTNMNGEVVPLSFALVLGWCSVMYFARGFQMLGPFTI 480
LGGPFHVIIITYASLVLLTMVMRLTNMNGEVVPLSFALVLGWCSVMYFARGFQMLGPFTI
Sbjct: 421 LGGPFHVIIITYASLVLLTMVMRLTNMNGEVVPLSFALVLGWCSVMYFARGFQMLGPFTI 480
Query: 481 MIQKMIFGDLMRFCWLMAVVILGFASAFHITFQTEDPNNLGEFSDYPTALFSTFELFLTI 540
MIQKMIFGDLMRFCWLMAVVILGFASAFHITFQTEDPNNLGEFSDYPTALFSTFELFLTI
Sbjct: 481 MIQKMIFGDLMRFCWLMAVVILGFASAFHITFQTEDPNNLGEFSDYPTALFSTFELFLTI 540
Query: 541 IDGPANYSVDLPFMYCITYAAFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVAT 600
IDGPANYSVDLPFMYCITYAAFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVAT
Sbjct: 541 IDGPANYSVDLPFMYCITYAAFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVAT 600
Query: 601 TVMLERKMPRFLWPRSGICGYEYGLGDRWFLRVENHHDQNPLRVLRYVEAFKCSDKEDGQ 660
TVMLERKMPRFLWPRSGICGYEYGLGDRWFLRVENHHDQNPLRVLRYVEAFKCSDKEDGQ
Sbjct: 601 TVMLERKMPRFLWPRSGICGYEYGLGDRWFLRVENHHDQNPLRVLRYVEAFKCSDKEDGQ 660
Query: 661 EQLSEKRPSTVESGMLSRASVAFQTPSLSRTTSQSSNSHRGWEILRRNTLGHLNLGLDLG 720
EQLSEKRPSTVESGMLSRASVAFQTPSLSRTTSQSSNSHRGWEILRRNTLGHLNLGLDLG
Sbjct: 661 EQLSEKRPSTVESGMLSRASVAFQTPSLSRTTSQSSNSHRGWEILRRNTLGHLNLGLDLG 720
Query: 721 EGDGEEVYHF 730
EGDGEEVYHF
Sbjct: 721 EGDGEEVYHF 730
>6BOA-A nrPDB
Length = 742
Score = 1069 bits (2764), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 538/727 (74%), Positives = 602/727 (82%), Gaps = 12/727 (1%)
Query: 1 MGACPPKAKGPWAQLQKLLISWPVGEQDWEQYRDRVNMLQQERIRDSPLLQAAKENDLRL 60
MG PK KG L W + W Q RD N+LQQ+RI +SPLL AAK+ND++
Sbjct: 1 MGLSLPKEKGLILCLWSKFCRWFQRRESWAQSRDEQNLLQQKRIWESPLLLAAKDNDVQA 60
Query: 61 LKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTA 120
L LL + C QRGA+GETALH+AALYDNLEAA +LMEAAPEL EP E + GQTA
Sbjct: 61 LNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTA 120
Query: 121 LHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVR 180
LHIAV+NQN+NLVRALLAR ASVSARATG AFRRSP NLIY+GEHPLSFAACV SEEIVR
Sbjct: 121 LHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVR 180
Query: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQG 240
LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD H DHLQ L+LVPNHQG
Sbjct: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQG 240
Query: 241 LTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSWGEELSFLELVVSSK 300
LTPFKLAGVEGNTVMFQHLMQKRKH QWT GPLTSTLYDLTEIDS G+E S LEL++++K
Sbjct: 241 LTPFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEIDSSGDEQSLLELIITTK 300
Query: 301 KREARQILEQTPVKELVSFKWKKYGRPYFCVLASLYILYMICFTTCCIYRPLKLRDDNRT 360
KREARQIL+QTPVKELVS KWK+YGRPYFC+L ++Y+LY+ICFT CCIYRPLK R +NRT
Sbjct: 301 KREARQILDQTPVKELVSLKWKRYGRPYFCMLGAIYLLYIICFTMCCIYRPLKPRTNNRT 360
Query: 361 DPRDITILQQKLLQEAYVTHQDNIRLVGELVTVTGAVIILLLEIPDIFRVGASRYFGQTI 420
PRD T+LQQKLLQEAY+T +D+IRLVGELVTV GA+IILL+E+PDIFR+G +R+FGQTI
Sbjct: 361 SPRDNTLLQQKLLQEAYMTPKDDIRLVGELVTVIGAIIILLVEVPDIFRMGVTRFFGQTI 420
Query: 421 LGGPFHVIIITYASLVLLTMVMRLTNMNGEVVPLSFALVLGWCSVMYFARGFQMLGPFTI 480
LGGPFHV+IITYA +VL+TMVMRL + +GEVVP+SFALVLGWC+VMYFA GFQMLGPFTI
Sbjct: 421 LGGPFHVLIITYAFMVLVTMVMRLISASGEVVPMSFALVLGWCNVMYFAEGFQMLGPFTI 480
Query: 481 MIQKMIFGDLMRFCWLMAVVILGFASAFHITFQTEDPNNLGEFSDYPTALFSTFELFLTI 540
MIQKMIFGDLMRFCWLMAVVILGFASAF+I FQTEDP LG F DYP ALFSTFELFLTI
Sbjct: 481 MIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPEELGHFYDYPMALFSTFELFLTI 540
Query: 541 IDGPANYSVDLPFMYCITYAAFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVAT 600
IDGPANY+VDLPFMY ITYAAFAIIATLLMLNL IAMMGDTHWRVA ERDELWRAQ+VAT
Sbjct: 541 IDGPANYNVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVAT 600
Query: 601 TVMLERKMPRFLWPRSGICGYEYGLGDRWFLRVENHHDQNPLRVLRYVEAFKCSDKEDGQ 660
TVMLERK+PR LWPRSGICG EYGLGDRWFLRVE+ D N R+ RY +AF ED
Sbjct: 601 TVMLERKLPRCLWPRSGICGREYGLGDRWFLRVEDRQDLNRQRIQRYAQAFHTRGSEDLD 660
Query: 661 EQLSEKRPSTVESGMLSRASVAFQTPSLSRTTSQSSNSHRGWEILRRNTL-----GHLNL 715
+ EK +E G ++ PS+SR+TS+SS + WE LR+ TL G +N
Sbjct: 661 KDSVEK----LELGCPFSPHLSLPMPSVSRSTSRSSAN---WERLRQGTLRRDLRGIINR 713
Query: 716 GLDLGEG 722
GL+ GE
Sbjct: 714 GLEDGES 720
>6E2G-A nrPDB
Length = 727
Score = 1069 bits (2764), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 541/734 (73%), Positives = 610/734 (83%), Gaps = 24/734 (3%)
Query: 1 MGACPPKAKGPWAQLQKLLISWPVGEQDWEQYRDRVNMLQQERIRDSPLLQAAKENDLRL 60
MG PK KG L W + W Q RD N+LQQ+RI +SPLL AAKEN+++
Sbjct: 1 MGWSLPKEKGLILCLWNKFCRWFHRRESWAQSRDEQNLLQQKRIWESPLLLAAKENNVQA 60
Query: 61 LKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTA 120
L LL + C+ Q+GA+GETALH+AALYDNLEAA +LMEAAPEL EP E + GQTA
Sbjct: 61 LIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTA 120
Query: 121 LHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVR 180
LHIAV+NQN+NLVRALLARGASVSARATG+ F PHNLIYYGEHPLSFAACVGSEEIVR
Sbjct: 121 LHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVR 180
Query: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQG 240
LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD DHL+SLELVPN+QG
Sbjct: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD-GGDHLKSLELVPNNQG 239
Query: 241 LTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSWGEELSFLELVVSSK 300
LTPFKLAGVEGN VMFQHLMQKRKH+QWT GPLTSTLYDLTEIDS G++ S LEL+V++K
Sbjct: 240 LTPFKLAGVEGNIVMFQHLMQKRKHIQWTYGPLTSTLYDLTEIDSSGDDQSLLELIVTTK 299
Query: 301 KREARQILEQTPVKELVSFKWKKYGRPYFCVLASLYILYMICFTTCCIYRPLKLRDDNRT 360
KREARQIL+QTPVKELVS KWK+YGRPYFCVL ++Y+LY+ICFT CC+YRPLK R NRT
Sbjct: 300 KREARQILDQTPVKELVSLKWKRYGRPYFCVLGAIYVLYIICFTMCCVYRPLKPRITNRT 359
Query: 361 DPRDITILQQKLLQEAYVTHQDNIRLVGELVTVTGAVIILLLEIPDIFRVGASRYFGQTI 420
+PRD T+LQQKLLQEAYVT +D++RLVGELV++ GAVIILL+EIPDIFR+G +R+FGQTI
Sbjct: 360 NPRDNTLLQQKLLQEAYVTPKDDLRLVGELVSIVGAVIILLVEIPDIFRLGVTRFFGQTI 419
Query: 421 LGGPFHVIIITYASLVLLTMVMRLTNMNGEVVPLSFALVLGWCSVMYFARGFQMLGPFTI 480
LGGPFHVII+TYA +VL+TMVMRLTN +GEVVP+SFALVLGWC+VMYFARGFQMLGPFTI
Sbjct: 420 LGGPFHVIIVTYAFMVLVTMVMRLTNSDGEVVPMSFALVLGWCNVMYFARGFQMLGPFTI 479
Query: 481 MIQKMIFGDLMRFCWLMAVVILGFASAFHITFQTEDPNNLGEFSDYPTALFSTFELFLTI 540
MIQKMIFGDLMRFCWLMAVVILGFASAF+I FQTEDP+ LG F DYP ALFSTFELFLTI
Sbjct: 480 MIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPDELGHFYDYPMALFSTFELFLTI 539
Query: 541 IDGPANYSVDLPFMYCITYAAFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVAT 600
IDGPANY VDLPFMY ITYAAFAIIATLLMLNL IAMMGDTHWRVA ERDELWRAQVVAT
Sbjct: 540 IDGPANYDVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQVVAT 599
Query: 601 TVMLERKMPRFLWPRSGICGYEYGLGDRWFLRVENHHDQNPLRVLRYVEAFKCSD----- 655
TVMLERK+PR LWPRSGICG EYGLGDRWFLRVE+ D N R+ RY +AF+ D
Sbjct: 600 TVMLERKLPRCLWPRSGICGREYGLGDRWFLRVEDRQDLNRQRIRRYAQAFQQQDDLYSE 659
Query: 656 --KEDGQEQLSEKRPSTVESGMLSRASVAFQTPSLSRTTSQSSNSHRGWEILRRNTL--- 710
++D E+L RP A ++F TPS+SR+TS+SS + W+ LR+ L
Sbjct: 660 DLEKDSGEKLEMARPFG--------AYLSFPTPSVSRSTSRSSTN---WDRLRQGALRKD 708
Query: 711 --GHLNLGLDLGEG 722
G +N GL+ GEG
Sbjct: 709 LQGIINRGLEDGEG 722
>2RFA-A nrPDB
Length = 232
Score = 361 bits (926), Expect = e-100, Method: Compositional matrix adjust.
Identities = 181/221 (81%), Positives = 195/221 (88%), Gaps = 1/221 (0%)
Query: 44 IRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAP 103
I +SPLL AAKEND++ L LL + C+ QRGA+GETALH+AALYDNLEAA +LMEAAP
Sbjct: 2 IWESPLLLAAKENDVQALSKLLKFEGCEVHQRGAMGETALHIAALYDNLEAAMVLMEAAP 61
Query: 104 ELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYG 163
EL EP E + GQTALHIAV+NQN+NLVRALLARGASVSARATG+ F PHNLIYYG
Sbjct: 62 ELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYG 121
Query: 164 EHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD 223
EHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD
Sbjct: 122 EHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD 181
Query: 224 EHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRK 264
DHL+SLELVPN+QGLTPFKLAGVEGN VMFQHLMQKRK
Sbjct: 182 G-GDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKRK 221
>6BBJ-A nrPDB
Length = 868
Score = 267 bits (683), Expect = 1e-71, Method: Compositional matrix adjust.
Identities = 186/577 (32%), Positives = 293/577 (50%), Gaps = 72/577 (12%)
Query: 115 FVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFR-RSPHNLIYYGEHPLSFAACV 173
+ GQTALHIA+ + + V L+ +GA V A+A G F+ + Y+GE PLS AAC
Sbjct: 232 YRGQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACT 291
Query: 174 GSEEIVRLLIEHG---ADIRAQDSLGNTVLHILI-----LQPNKTFACQMYNLLLSYDEH 225
+IV L E+ ADIR QDS GNTVLH L+ + N F ++Y+LL+
Sbjct: 292 NQPDIVHYLTENAHKKADIRRQDSRGNTVLHALVAIADNTRENTKFVTKVYDLLVIKCVK 351
Query: 226 SDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQ-----------KRKHVQWTCGPLT 274
SLE + N+ ++P +A G +FQH+++ RK W GP+
Sbjct: 352 LYPDSSLEAIFNNDSMSPLMMAAKLGKIGIFQHIIRLEIKDEEARHLSRKFRDWAYGPVY 411
Query: 275 STLYDLTEIDSWGEELSFLELVVSSKKREAR-QILEQTPVKELVSFKWKKYGRPYFCVLA 333
S+LYDL+ +D+ GEE+S LE++V + K E R ++L P+ EL+ KW+K+G F +
Sbjct: 412 SSLYDLSMLDTCGEEVSVLEILVYNSKVENRHEMLAVEPINELLRDKWQKFGAVSFYISV 471
Query: 334 SLYILYMICFTTCCIYRPLKLRDDNRTDPRDITILQQKLLQEAYVTHQDNIRLVGELVTV 393
Y++ MI FT YRP+ + T P Y T D +RL GE+VT+
Sbjct: 472 VSYLIAMIIFTLIAYYRPM-----DGTPPY------------PYRTTMDYMRLAGEIVTL 514
Query: 394 TGAVIILLLEIPDIFRV---GASRYFGQTILGGPFHVIIITYASLVLLTMVMRLTNMNGE 450
V+ + I D+F G + F + G F ++ Y+ LV++T V+ L +
Sbjct: 515 LTGVVFFITNIKDLFMKKCPGVNSLF----IDGSFQLLYFIYSVLVIITAVLYLVGIESY 570
Query: 451 VVPLSFALVLGWCSVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAF-- 508
+ + FALVLGW + +YF RG ++ G ++IM+QK++F DL RF + + ++G+ASA
Sbjct: 571 LAVMVFALVLGWMNALYFTRGLKLTGTYSIMLQKILFKDLFRFLLVYLLFMIGYASALVS 630
Query: 509 --------HITFQTEDPNNLGEF------SDYPTALFSTFELFLTIIDGPANYSVDLPFM 554
+T + E+ S + L F+L + + D S P +
Sbjct: 631 LLNPCTSQESCIETSSNCTVPEYPSCRDSSTFSKFLLDLFKLTIGMGDLEMINSAKYPAV 690
Query: 555 YCITYAAFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVATTVMLERKMPRFLWP 614
+ I + I+ +L+LN+ IA+MG+T +V++E ++W+ Q T + +ER P +
Sbjct: 691 FIILLVTYIILTFVLLLNMLIALMGETVGQVSKESKQIWKLQWATTILDIERSFPVCMRK 750
Query: 615 --RSG----ICGYEYGLGD-RWFLRVE----NHHDQN 640
RSG + G D RW RV+ +H +QN
Sbjct: 751 AFRSGEMVTVGKNLDGTPDRRWCFRVDEVNWSHWNQN 787
>6C8G-A nrPDB
Length = 675
Score = 267 bits (682), Expect = 1e-71, Method: Compositional matrix adjust.
Identities = 186/575 (32%), Positives = 292/575 (50%), Gaps = 72/575 (12%)
Query: 117 GQTALHIAVMNQNLNLVRALLARGASVSARATGAAFR-RSPHNLIYYGEHPLSFAACVGS 175
GQTALHIA+ + + V L+ +GA V A+A G F+ + Y+GE PLS AAC
Sbjct: 103 GQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQ 162
Query: 176 EEIVRLLIEHG---ADIRAQDSLGNTVLHILI-----LQPNKTFACQMYNLLLSYDEHSD 227
+IV L E+ ADIR QDS GNTVLH L+ + N F ++Y+LL+
Sbjct: 163 PDIVHYLTENAHKKADIRRQDSRGNTVLHALVAIADNTRENTKFVTKVYDLLVIKCVKLY 222
Query: 228 HLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQ-----------KRKHVQWTCGPLTST 276
SLE + N+ ++P +A G +FQH+++ RK W GP+ S+
Sbjct: 223 PDSSLEAIFNNDSMSPLMMAAKLGKIGIFQHIIRLEIKDEEARHLSRKFRDWAYGPVYSS 282
Query: 277 LYDLTEIDSWGEELSFLELVVSSKKREAR-QILEQTPVKELVSFKWKKYGRPYFCVLASL 335
LYDL+ +D+ GEE+S LE++V + K E R ++L P+ EL+ KW+K+G F +
Sbjct: 283 LYDLSMLDTCGEEVSVLEILVYNSKVENRHEMLAVEPINELLRDKWQKFGAVSFYISVVS 342
Query: 336 YILYMICFTTCCIYRPLKLRDDNRTDPRDITILQQKLLQEAYVTHQDNIRLVGELVTVTG 395
Y++ MI FT YRP+ + T P Y T D +RL GE+VT+
Sbjct: 343 YLIAMIIFTLIAYYRPM-----DGTPPY------------PYRTTMDYMRLAGEIVTLLT 385
Query: 396 AVIILLLEIPDIFRV---GASRYFGQTILGGPFHVIIITYASLVLLTMVMRLTNMNGEVV 452
V+ + I D+F G + F + G F ++ Y+ LV++T V+ L + +
Sbjct: 386 GVVFFITNIKDLFMKKCPGVNSLF----IDGSFQLLYFIYSVLVIITAVLYLVGIESYLA 441
Query: 453 PLSFALVLGWCSVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAF---- 508
+ FALVLGW + +YF RG ++ G ++IM+QK++F DL RF + + ++G+ASA
Sbjct: 442 VMVFALVLGWMNALYFTRGLKLTGTYSIMLQKILFKDLFRFLLVYLLFMIGYASALVSLL 501
Query: 509 ------HITFQTEDPNNLGEF------SDYPTALFSTFELFLTIIDGPANYSVDLPFMYC 556
+T + E+ S + L F+L + + D S P ++
Sbjct: 502 NPCTSQESCIETSSQCTVPEYPSCRDSSTFSKFLLDLFKLTIGMGDLEMINSAKYPAVFI 561
Query: 557 ITYAAFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVATTVMLERKMPRFLWP-- 614
I + I+ +L+LN+ IA+MG+T +V++E ++W+ Q T + +ER P +
Sbjct: 562 ILLVTYIILTFVLLLNMLIALMGETVGQVSKESKQIWKLQWATTILDIERSFPVCMRKAF 621
Query: 615 RSG----ICGYEYGLGD-RWFLRVE----NHHDQN 640
RSG + G D RW RV+ +H +QN
Sbjct: 622 RSGEMVTVGKNLDGTPDRRWCFRVDEVNWSHWNQN 656
>5IRX-A nrPDB
Length = 636
Score = 233 bits (594), Expect = 2e-61, Method: Compositional matrix adjust.
Identities = 169/556 (30%), Positives = 274/556 (49%), Gaps = 68/556 (12%)
Query: 115 FVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNL-IYYGEHPLSFAACV 173
+ GQTALHIA+ +N+ LV L+ GA V A A G F+++ Y+GE PLS AAC
Sbjct: 94 YKGQTALHIAIERRNMTLVTLLVENGADVQAAANGDFFKKTKGRPGFYFGELPLSLAACT 153
Query: 174 GSEEIVRLLIEHG---ADIRAQDSLGNTVLHILILQPNKT-----FACQMYNLLLSYDEH 225
IV+ L+++ ADI A+DS+GNTVLH L+ + T F MYN +L
Sbjct: 154 NQLAIVKFLLQNSWQPADISARDSVGNTVLHALVEVADNTVDNTKFVTSMYNEILILGAK 213
Query: 226 SDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQK-----------RKHVQWTCGPLT 274
LE + N +GLTP LA G + +++Q+ RK +W GP+
Sbjct: 214 LHPTLKLEEITNRKGLTPLALAASSGKIGVLAYILQREIHEPECRHLSRKFTEWAYGPVH 273
Query: 275 STLYDLTEIDSWGEELSFLELVV--SSKKREARQILEQTPVKELVSFKWKKYGRPYFCVL 332
S+LYDL+ ID+ E+ S LE++ SS+ +L P+ L+ KW ++ + F
Sbjct: 274 SSLYDLSCIDT-CEKNSVLEVIAYSSSETPNRHDMLLVEPLNRLLQDKWDRFVKRIFYFN 332
Query: 333 ASLYILYMICFTTCCIYRPL------KLRDDNRTDPRDITILQQKLLQEAYVTHQDNIRL 386
+Y LYMI FT YRP+ KL++ T D R+
Sbjct: 333 FFVYCLYMIIFTAAAYYRPVEGLPPYKLKN----------------------TVGDYFRV 370
Query: 387 VGELVTVTGAVIILLLEIPDIFRVGASRYFGQTILGGPFHVIIITYASL-VLLTMVMRLT 445
GE+++V+G V I + S +++ + I+ SL +L+++V+ +
Sbjct: 371 TGEILSVSGGVYFFFRGIQYFLQRRPSL---KSLFVDSYSEILFFVQSLFMLVSVVLYFS 427
Query: 446 NMNGEVVPLSFALVLGWCSVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFA 505
V + F+L +GW +++Y+ RGFQ +G + +MI+KMI DL RF ++ V + GF+
Sbjct: 428 QRKEYVASMVFSLAMGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYLVFLFGFS 487
Query: 506 SAFHITFQTEDPNNLGEFSDYPTALFSTFELFLTIIDGPANYSVDLPFMYCITYAAFAII 565
+A + ED G+++ + F+ + + D + D ++ I A+ I+
Sbjct: 488 TA--VVTLIED----GKYNSLYSTCLELFKFTIGMGDLEFTENYDFKAVFIILLLAYVIL 541
Query: 566 ATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVATTVMLERKMPRFLWP--RSGI---CG 620
+L+LN+ IA+MG+T ++AQE +W+ Q T + E+ + + RSG G
Sbjct: 542 TYILLLNMLIALMGETVNKIAQESKNIWKLQRAITILDTEKSFLKCMRKAFRSGKLLQVG 601
Query: 621 YEYGLGD--RWFLRVE 634
+ D RW RV+
Sbjct: 602 FTPDGKDDYRWCFRVD 617
Score = 30.8 bits (68), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 18/39 (46%), Positives = 21/39 (53%), Gaps = 2/39 (5%)
Query: 48 PLLQAAKENDLRLLKILLLN--QSCDFQQRGAVGETALH 84
PL AA N L ++K LL N Q D R +VG T LH
Sbjct: 146 PLSLAACTNQLAIVKFLLQNSWQPADISARDSVGNTVLH 184
>6DVZ-A nrPDB
Length = 791
Score = 230 bits (586), Expect = 2e-60, Method: Compositional matrix adjust.
Identities = 157/526 (29%), Positives = 271/526 (51%), Gaps = 45/526 (8%)
Query: 113 EPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFR-RSPHNLIYYGEHPLSFAA 171
E + GQTAL+IA+ + ++ L+A GA V+A A G F + H Y+GE PL+ AA
Sbjct: 211 EAYEGQTALNIAIERRQGDITAVLIAAGADVNAHAKGVFFNPKYQHEGFYFGETPLALAA 270
Query: 172 CVGSEEIVRLLIEH-GADIRAQDSLGNTVLHILI-----LQPNKTFACQMYNLLLSYDEH 225
C EIV+LL+E+ DI +QDS GN +LH L+ + F +MY+++L +
Sbjct: 271 CTNQPEIVQLLMENEQTDITSQDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILLRSGN 330
Query: 226 SDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQK-----------RKHVQWTCGPLT 274
+ LE + N+ GLTP +LA G + ++++ + RK W GP++
Sbjct: 331 WE----LETMRNNDGLTPLQLAAKMGKAEILKYILSREIKEKPLRSLSRKFTDWAYGPVS 386
Query: 275 STLYDLTEIDSWGEELSFLELVVSSKKREAR-QILEQTPVKELVSFKWKKYGRPYFCVLA 333
S+LYDLT +D+ + S LE++V + + R ++L P+ L+ KWKK+ + F +
Sbjct: 387 SSLYDLTNVDTTTDN-SVLEIIVYNTNIDNRHEMLTLEPLHTLLHTKWKKFAKYMFFLSF 445
Query: 334 SLYILYMICFTTCCIYRPLKLRDDNRTDPRDITILQQKLLQEAYVTHQDN-IRLVGELVT 392
Y Y I T YRP R+D + L +TH+ + ++L+G +
Sbjct: 446 CFYFFYNITLTLVSYYRP---RED------------EDLPHPLALTHKMSWLQLLGRMFV 490
Query: 393 VTGAVIILLLEIPDIFRVGASRYFGQTILGGP-FHVIIITYASLVLLTMVMRLTNMNGEV 451
+ A I + E IF + S Q+IL FH + A LV+L++ + L +
Sbjct: 491 LIWATCISVKEGIAIFLLRPSDL--QSILSDAWFHFVFFVQAVLVILSVFLYLFAYKEYL 548
Query: 452 VPLSFALVLGWCSVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFHIT 511
L A+ LGW +++ + RGFQ +G +++MIQK+I D+++F ++ + +LGF A
Sbjct: 549 ACLVLAMALGWANMLAYTRGFQSMGMYSVMIQKVILHDVLKFLFVYILFLLGFGVALASL 608
Query: 512 FQ--TEDPNNLGEFSDYPTALFSTFELFLTIIDGPANYSVDLPFMYCITYAAFAIIATLL 569
+ ++D + + + A+ F+L + + D + P ++ + I+ +L
Sbjct: 609 IEKCSKDKKDCSSYGSFSDAVLELFKLTIGLGDLNIQQNSTYPILFLFLLITYVILTFVL 668
Query: 570 MLNLFIAMMGDTHWRVAQERDELWRAQVVATTVMLERKMPRFLWPR 615
+LN+ IA+MG+T V++E + +WR Q T + E+ +P +L R
Sbjct: 669 LLNMLIALMGETVENVSKESERIWRLQRARTILEFEKMLPEWLRSR 714
>6MHW-A nrPDB
Length = 826
Score = 223 bits (569), Expect = 2e-58, Method: Compositional matrix adjust.
Identities = 161/529 (30%), Positives = 272/529 (51%), Gaps = 51/529 (9%)
Query: 113 EPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFR-RSPHNLIYYGEHPLSFAA 171
E + GQTAL+IA+ + ++ L+A GA V+A A GA F + H Y+GE PL+ AA
Sbjct: 212 EAYEGQTALNIAIERRQGDIAALLIAAGADVNAHAKGAFFNPKYQHEGFYFGETPLALAA 271
Query: 172 CVGSEEIVRLLIEH-GADIRAQDSLGNTVLHILI-----LQPNKTFACQMYNLLLSYDEH 225
C EIV+LL+EH DI ++DS GN +LH L+ + F +MY+++L +
Sbjct: 272 CTNQPEIVQLLMEHEQTDITSRDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILLRSGN 331
Query: 226 SDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQK-----------RKHVQWTCGPLT 274
+ LE N+ GLTP +LA G + ++++ + RK W GP++
Sbjct: 332 WE----LETTRNNDGLTPLQLAAKMGKAEILKYILSREIKEKRLRSLSRKFTDWAYGPVS 387
Query: 275 STLYDLTEIDSWGEELSFLELVVSSKKREAR-QILEQTPVKELVSFKWKKYGRPYFCVLA 333
S+LYDLT +D+ + S LE+ V + + R ++L P+ L+ KWKK+ + F +
Sbjct: 388 SSLYDLTNVDTTTDN-SVLEITVYNTNIDNRHEMLTLEPLHTLLHMKWKKFAKHMFFLSF 446
Query: 334 SLYILYMICFTTCCIYRPLKLRDDNRTDPRDITILQQKLLQEAYVTHQDN-IRLVGELVT 392
Y Y I T YRP + ++ + +TH+ ++L+G +
Sbjct: 447 CFYFFYNITLTLVSYYRPRE---------------EEAIPHPLALTHKMGWLQLLGRMFV 491
Query: 393 VTGAVIILLLEIPDIFRVGASRYFGQTILGGP-FHVIIITYASLVLLTMVMRLTNMNGEV 451
+ A+ I + E IF + S Q+IL FH + A LV+L++ + L +
Sbjct: 492 LIWAMCISVKEGIAIFLLRPSDL--QSILSDAWFHFVFFIQAVLVILSVFLYLFAYKEYL 549
Query: 452 VPLSFALVLGWCSVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFHIT 511
L A+ LGW +++Y+ RGFQ +G +++MIQK+I D+++F ++ V +LGF A
Sbjct: 550 ACLVLAMALGWANMLYYTRGFQSMGMYSVMIQKVILHDVLKFLFVYIVFLLGFGVALASL 609
Query: 512 FQ-----TEDPNNLGEFSDYPTALFSTFELFLTIIDGPANYSVDLPFMYCITYAAFAIIA 566
+ +D ++ G FSD A+ F+L + + D + P ++ + I+
Sbjct: 610 IEKCPKDNKDCSSYGSFSD---AVLELFKLTIGLGDLNIQQNSKYPILFLFLLITYVILT 666
Query: 567 TLLMLNLFIAMMGDTHWRVAQERDELWRAQVVATTVMLERKMPRFLWPR 615
+L+LN+ IA+MG+T V++E + +WR Q T + E+ +P +L R
Sbjct: 667 FVLLLNMLIALMGETVENVSKESERIWRLQRARTILEFEKMLPEWLRSR 715
>5AN8-A nrPDB
Length = 613
Score = 196 bits (497), Expect = 4e-50, Method: Compositional matrix adjust.
Identities = 172/565 (30%), Positives = 286/565 (50%), Gaps = 61/565 (10%)
Query: 76 GAVGETALHVAALYDNL-EAATLLMEAAPELAKEPALCEPFV----------GQTALHIA 124
G+ G+T L A L NL + ++ E+ ++ +P V G +ALHIA
Sbjct: 37 GSTGKTCLMKAVL--NLQDGVNACIQPLLEIDRDSGNPQPLVNAQCTDEYYRGHSALHIA 94
Query: 125 VMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIE 184
+ ++L V+ L+ GA+V A+A G F+++ Y+GE PLS AAC ++V L+E
Sbjct: 95 IEKRSLQCVKLLVENGANVHAKACGHFFQKNQDTCFYFGELPLSLAACTKQWDVVNYLLE 154
Query: 185 H---GADIRAQDSLGNTVLHILIL-----QPNKTFACQMYNLLLSYDEHSDHLQSLELVP 236
+ A ++AQDSLGNTVLH L++ N +MY+ LL LE +P
Sbjct: 155 NPHPAASLQAQDSLGNTVLHALVMIADNSPENSALVVRMYDGLLQAGARLCPNVQLEGIP 214
Query: 237 NHQGLTPFKLAGVEGNTVMFQHLMQK----------RKHVQWTCGPLTSTLYDLTEIDSW 286
N +GLTP KLA EG +F+H++Q+ RK +W GP+ +LYDL +DSW
Sbjct: 215 NLEGLTPLKLAAKEGKIEIFKHILQREFSAPCQSLSRKFTEWCYGPVRVSLYDLASVDSW 274
Query: 287 GEELSFLELVV---SSKKREARQILEQTPVKELVSFKWKKYGRPYFCVLASLYILYMICF 343
EE S LE++ S R +LE P+ +L+ KW + P FC Y++YM+ F
Sbjct: 275 -EENSVLEIIAFHSRSPHRHRMVVLE--PLNKLLQAKWDRL-IPRFCFNFLCYLVYMLIF 330
Query: 344 TTCCIYRPLKLRDDNRTDPRDITILQQKLLQEAYVTHQDNIRLVGELVTVTGAVIILLLE 403
T ++P L+++ T +++ L+G ++ + G V +LL +
Sbjct: 331 TAVAYHQP---------------ALEKQGFPPLKATAGNSMLLLGHILILLGGVYLLLGQ 375
Query: 404 IPDIFRVGASRYFGQTILGGPFHVIIITYASLVLLTMVMRLTNMNGEVVPLSFALVLGWC 463
+ +R + + + F ++ + A L +L+ V+ + + L +LVLGW
Sbjct: 376 LWYFWR--RRLFIWISFMDSYFEILFLLQALLTVLSQVLCFLAIEWYLPLLVSSLVLGWL 433
Query: 464 SVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFHITFQTEDPNNLGEF 523
+++Y+ RGFQ G +++MIQK+I DL+RF + V + GFA A ++ E + E
Sbjct: 434 NLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVAL-VSLSREAQED--EA 490
Query: 524 SDYPTALFSTFELF-LTIIDGPANYSVDLPF--MYCITYAAFAIIATLLMLNLFIAMMGD 580
Y + L ++ ELF TI G + L F + + A+ ++ +L+LN+ IA+M +
Sbjct: 491 PPYRSILDASLELFKFTIGMGELAFQEQLRFRGVVLLLLLAYVLLTYVLLLNMLIALMSE 550
Query: 581 THWRVAQERDELWRAQVVATTVMLE 605
T VA + +W+ Q + + +E
Sbjct: 551 TVNSVATDSWSIWKLQKAISVLEME 575
>5HI9-A nrPDB
Length = 770
Score = 182 bits (462), Expect = 5e-46, Method: Compositional matrix adjust.
Identities = 173/580 (29%), Positives = 282/580 (48%), Gaps = 71/580 (12%)
Query: 76 GAVGETALHVAAL--YDNLEAATLLMEAAPELAKEP-----ALC--EPFVGQTALHIAVM 126
G+ G+T L A L D + A + + + + P A C E + G +ALHIA+
Sbjct: 114 GSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKPLVNAQCTDEFYQGHSALHIAIE 173
Query: 127 NQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHG 186
++L V+ L+ GA V RA G F++ Y+GE PLS AAC ++V L+E+
Sbjct: 174 KRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENP 233
Query: 187 ---ADIRAQDSLGNTVLHILIL-----QPNKTFACQMYNLLLSYDEHSDHLQSLELVPNH 238
A + A DSLGNTVLH L++ N MY+ LL LE + NH
Sbjct: 234 HQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNH 293
Query: 239 QGLTPFKLAGVEGNTVMFQHLMQK----------RKHVQWTCGPLTSTLYDLTEIDSWGE 288
QGLTP KLA EG +F+H++Q+ RK +W GP+ +LYDL+ +DSW E
Sbjct: 294 QGLTPLKLAAKEGKIEIFRHILQREFSGPYQPLSRKFTEWCYGPVRVSLYDLSSVDSW-E 352
Query: 289 ELSFLELVV---SSKKREARQILEQTPVKELVSFKWKKYGRPYFCVLASLYILYMICFTT 345
+ S LE++ S R +LE P+ +L+ KW + +F A Y++YM FT
Sbjct: 353 KNSVLEIIAFHCKSPNRHRMVVLE--PLNKLLQEKWDRLVSRFFFNFAC-YLVYMFIFTV 409
Query: 346 CCIYRPLKLRDDNRTDPRDITILQQKLLQEAYVTHQDNIRLVGELVTVTGAVIILLLEIP 405
++P L Q + + T +++ L+G ++ + G + +LL ++
Sbjct: 410 VAYHQP---------------SLDQPAIPSSKATFGESMLLLGHILILLGGIYLLLGQLW 454
Query: 406 DIFRVGASRYFGQTILGGPFHVIIITYASLVLLTMVMRLTNMNGEVVPLSFALVLGWCSV 465
+R + + + F ++ + A L +L+ V+R + L +LVLGW ++
Sbjct: 455 YFWR--RRLFIWISFMDSYFEILFLLQALLTVLSQVLRFMETEWYLPLLVLSLVLGWLNL 512
Query: 466 MYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAF-HITFQTEDP----NNL 520
+Y+ RGFQ G +++MIQK+I DL+RF + V + GFA A ++ + P +N
Sbjct: 513 LYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVSLSREARSPKAPEDNN 572
Query: 521 GEFSDYPTA------------LFSTFELF-LTIIDGPANYSVDLPF--MYCITYAAFAII 565
++ PT L ++ ELF TI G + L F + + A+ ++
Sbjct: 573 STVTEQPTVGQEEEPAPYRSILDASLELFKFTIGMGELAFQEQLRFRGVVLLLLLAYVLL 632
Query: 566 ATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVATTVMLE 605
+L+LN+ IA+M +T VA +W+ Q + + +E
Sbjct: 633 TYVLLLNMLIALMSETVNHVADNSWSIWKLQKAISVLEME 672
>6BO5-A nrPDB
Length = 695
Score = 182 bits (462), Expect = 5e-46, Method: Compositional matrix adjust.
Identities = 173/580 (29%), Positives = 282/580 (48%), Gaps = 71/580 (12%)
Query: 76 GAVGETALHVAAL--YDNLEAATLLMEAAPELAKEP-----ALC--EPFVGQTALHIAVM 126
G+ G+T L A L D + A + + + + P A C E + G +ALHIA+
Sbjct: 74 GSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKPLVNAQCTDEFYQGHSALHIAIE 133
Query: 127 NQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHG 186
++L V+ L+ GA V RA G F++ Y+GE PLS AAC ++V L+E+
Sbjct: 134 KRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENP 193
Query: 187 ---ADIRAQDSLGNTVLHILIL-----QPNKTFACQMYNLLLSYDEHSDHLQSLELVPNH 238
A + A DSLGNTVLH L++ N MY+ LL LE + NH
Sbjct: 194 HQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNH 253
Query: 239 QGLTPFKLAGVEGNTVMFQHLMQK----------RKHVQWTCGPLTSTLYDLTEIDSWGE 288
QGLTP KLA EG +F+H++Q+ RK +W GP+ +LYDL+ +DSW E
Sbjct: 254 QGLTPLKLAAKEGKIEIFRHILQREFSGPYQPLSRKFTEWCYGPVRVSLYDLSSVDSW-E 312
Query: 289 ELSFLELVV---SSKKREARQILEQTPVKELVSFKWKKYGRPYFCVLASLYILYMICFTT 345
+ S LE++ S R +LE P+ +L+ KW + +F A Y++YM FT
Sbjct: 313 KNSVLEIIAFHCKSPNRHRMVVLE--PLNKLLQEKWDRLVSRFFFNFAC-YLVYMFIFTV 369
Query: 346 CCIYRPLKLRDDNRTDPRDITILQQKLLQEAYVTHQDNIRLVGELVTVTGAVIILLLEIP 405
++P L Q + + T +++ L+G ++ + G + +LL ++
Sbjct: 370 VAYHQP---------------SLDQPAIPSSKATFGESMLLLGHILILLGGIYLLLGQLW 414
Query: 406 DIFRVGASRYFGQTILGGPFHVIIITYASLVLLTMVMRLTNMNGEVVPLSFALVLGWCSV 465
+R + + + F ++ + A L +L+ V+R + L +LVLGW ++
Sbjct: 415 YFWR--RRLFIWISFMDSYFEILFLLQALLTVLSQVLRFMETEWYLPLLVLSLVLGWLNL 472
Query: 466 MYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAF-HITFQTEDP----NNL 520
+Y+ RGFQ G +++MIQK+I DL+RF + V + GFA A ++ + P +N
Sbjct: 473 LYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVSLSREARSPKAPEDNN 532
Query: 521 GEFSDYPTA------------LFSTFELF-LTIIDGPANYSVDLPF--MYCITYAAFAII 565
++ PT L ++ ELF TI G + L F + + A+ ++
Sbjct: 533 STVTEQPTVGQEEEPAPYRSILDASLELFKFTIGMGELAFQEQLRFRGVVLLLLLAYVLL 592
Query: 566 ATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVATTVMLE 605
+L+LN+ IA+M +T VA +W+ Q + + +E
Sbjct: 593 TYVLLLNMLIALMSETVNHVADNSWSIWKLQKAISVLEME 632
>6OO7-A nrPDB
Length = 786
Score = 159 bits (401), Expect = 6e-39, Method: Compositional matrix adjust.
Identities = 107/308 (34%), Positives = 161/308 (52%), Gaps = 38/308 (12%)
Query: 76 GAVGETALHVAALYDNL-EAATLLMEAAPELAKEPALCEPFV----------GQTALHIA 124
G+ G+T L A L NL + ++ E+ ++ +P V G +ALHIA
Sbjct: 112 GSTGKTCLMKAVL--NLQDGVNACIQPLLEIDRDSGNPQPLVNAQCTDEYYRGHSALHIA 169
Query: 125 VMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIE 184
+ ++L V+ L+ GA+V A+A G F+++ Y+GE PLS AAC ++V L+E
Sbjct: 170 IEKRSLQCVKLLVENGANVHAKACGHFFQKNQDTCFYFGELPLSLAACTKQWDVVNYLLE 229
Query: 185 H---GADIRAQDSLGNTVLHILIL-----QPNKTFACQMYNLLLSYDEHSDHLQSLELVP 236
+ A ++AQDSLGNTVLH L++ N +MY+ LL LE +P
Sbjct: 230 NPHQPASLQAQDSLGNTVLHALVMIADDSAENSALVVRMYDGLLQAGARLCPNVQLEGIP 289
Query: 237 NHQGLTPFKLAGVEGNTVMFQHLMQK----------RKHVQWTCGPLTSTLYDLTEIDSW 286
N +GLTP KLA EG +F+H++Q+ RK +W GP+ +LYDL +DSW
Sbjct: 290 NLEGLTPLKLAAKEGKIEIFKHILQREFSAPCQSLSRKFTEWCYGPVRVSLYDLASVDSW 349
Query: 287 GEELSFLELVV---SSKKREARQILEQTPVKELVSFKWKKYGRPYFCVLASLYILYMICF 343
EE S LE++ S R +LE P+ +L+ KW + P FC Y++YM+ F
Sbjct: 350 -EENSVLEIIAFHSRSPHRHRMVVLE--PLNKLLQAKWDRL-IPRFCFNFLCYLVYMLIF 405
Query: 344 TTCCIYRP 351
T ++P
Sbjct: 406 TAVAYHQP 413
>2ETB-A nrPDB
Length = 256
Score = 109 bits (272), Expect = 5e-24, Method: Compositional matrix adjust.
Identities = 74/206 (35%), Positives = 105/206 (50%), Gaps = 17/206 (8%)
Query: 75 RGAVGETALHVAAL--YDNLEAATLLMEAAPELAKEP-----ALC--EPFVGQTALHIAV 125
G+ G+T L A L D + A + + + + P A C E + G +ALHIA+
Sbjct: 39 EGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKPLVNAQCTDEFYQGHSALHIAI 98
Query: 126 MNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEH 185
++L V+ L+ GA V RA G F++ Y+GE PLS AAC ++V L+E+
Sbjct: 99 EKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLEN 158
Query: 186 ---GADIRAQDSLGNTVLHILIL-----QPNKTFACQMYNLLLSYDEHSDHLQSLELVPN 237
A + A DSLGNTVLH L++ N MY+ LL LE + N
Sbjct: 159 PHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISN 218
Query: 238 HQGLTPFKLAGVEGNTVMFQHLMQKR 263
HQGLTP KLA EG +F+H++Q+
Sbjct: 219 HQGLTPLKLAAKEGKIEIFRHILQRE 244
>2NYJ-A nrPDB
Length = 273
Score = 103 bits (257), Expect = 2e-22, Method: Compositional matrix adjust.
Identities = 62/160 (38%), Positives = 87/160 (54%), Gaps = 9/160 (5%)
Query: 115 FVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNL-IYYGEHPLSFAACV 173
+ GQTALHIA+ +N+ LV L+ GA V A A G F+++ Y+GE PLS AAC
Sbjct: 99 YKGQTALHIAIERRNMTLVTLLVENGADVQAAANGDFFKKTKGRPGFYFGELPLSLAACT 158
Query: 174 GSEEIVRLLIEHG---ADIRAQDSLGNTVLHILILQPNKT-----FACQMYNLLLSYDEH 225
IV+ L+++ ADI A+DS+GNTVLH L+ + T F MYN +L
Sbjct: 159 NQLAIVKFLLQNSWQPADISARDSVGNTVLHALVEVADNTVDNTKFVTSMYNEILILGAK 218
Query: 226 SDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKH 265
LE + N +GLTP LA G + +++Q+ H
Sbjct: 219 LHPTLKLEEITNRKGLTPLALAASSGKIGVLAYILQREIH 258
Score = 30.0 bits (66), Expect = 4.2, Method: Compositional matrix adjust.
Identities = 18/40 (45%), Positives = 21/40 (52%), Gaps = 2/40 (5%)
Query: 48 PLLQAAKENDLRLLKILLLN--QSCDFQQRGAVGETALHV 85
PL AA N L ++K LL N Q D R +VG T LH
Sbjct: 151 PLSLAACTNQLAIVKFLLQNSWQPADISARDSVGNTVLHA 190
>2F37-A nrPDB
Length = 251
Score = 100 bits (250), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 72/204 (35%), Positives = 104/204 (50%), Gaps = 17/204 (8%)
Query: 76 GAVGETALHVAAL--YDNLEAATLLMEAAPELAKEP-----ALC--EPFVGQTALHIAVM 126
G+ G+T L A L D + A L + + P A C + + G +ALHIA+
Sbjct: 45 GSTGKTCLMKAVLNLKDGVNACILPLLQIDRDSGNPQPLVNAQCTDDYYRGHSALHIAIE 104
Query: 127 NQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEH- 185
++L V+ L+ GA+V ARA G F++ Y+GE PLS AAC ++V L+E+
Sbjct: 105 KRSLQCVKLLVENGANVHARACGRFFQKGQGTCFYFGELPLSLAACTKQWDVVSYLLENP 164
Query: 186 --GADIRAQDSLGNTVLHILIL-----QPNKTFACQMYNLLLSYDEHSDHLQSLELVPNH 238
A ++A DS GNTVLH L++ N MY+ LL LE + N
Sbjct: 165 HQPASLQATDSQGNTVLHALVMISDNSAENIALVTSMYDGLLQAGARLCPTVQLEDIRNL 224
Query: 239 QGLTPFKLAGVEGNTVMFQHLMQK 262
Q LTP KLA EG +F+H++Q+
Sbjct: 225 QDLTPLKLAAKEGKIEIFRHILQR 248
>4DX2-A nrPDB
Length = 259
Score = 100 bits (248), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 63/157 (40%), Positives = 88/157 (56%), Gaps = 9/157 (5%)
Query: 115 FVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFR-RSPHNLIYYGEHPLSFAACV 173
+ GQTALHIA+ + + V L+A+GA V A+A G F+ + Y+GE PLS AAC
Sbjct: 89 YRGQTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACT 148
Query: 174 GSEEIVRLLIEH---GADIRAQDSLGNTVLHILI-----LQPNKTFACQMYNLLLSYDEH 225
IV L E+ AD+R QDS GNTVLH L+ + N F +MY+LLL
Sbjct: 149 NQPHIVNYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLLKCAR 208
Query: 226 SDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQK 262
+LE V N+ GL+P +A G +FQH++++
Sbjct: 209 LFPDSNLEAVLNNDGLSPLMMAAKTGKIGIFQHIIRR 245
>3W9G-A nrPDB
Length = 260
Score = 100 bits (248), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 62/157 (39%), Positives = 88/157 (56%), Gaps = 9/157 (5%)
Query: 115 FVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFR-RSPHNLIYYGEHPLSFAACV 173
+ GQTALHIA+ + + V L+ +GA V A+A G F+ + Y+GE PLS AAC
Sbjct: 91 YRGQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACT 150
Query: 174 GSEEIVRLLIEHG---ADIRAQDSLGNTVLHILI-----LQPNKTFACQMYNLLLSYDEH 225
IV L E+G AD+R QDS GNTVLH L+ + N F +MY+LLL
Sbjct: 151 NQPHIVHYLTENGHKQADLRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLIKCAK 210
Query: 226 SDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQK 262
+LE + N+ GL+P +A G +FQH++++
Sbjct: 211 LFPDTNLEALLNNDGLSPLMMAAKTGKIGIFQHIIRR 247
>4N5Q-A nrPDB
Length = 257
Score = 94.7 bits (234), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 56/157 (35%), Positives = 89/157 (56%), Gaps = 11/157 (7%)
Query: 113 EPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFR-RSPHNLIYYGEHPLSFAA 171
E + GQTAL+IA+ + ++ L+A GA V+A A G F + H Y+GE PL+ AA
Sbjct: 95 EAYEGQTALNIAIERRQGDITAVLIAAGADVNAHAKGVFFNPKYQHEGFYFGETPLALAA 154
Query: 172 CVGSEEIVRLLIEH-GADIRAQDSLGNTVLHILI-----LQPNKTFACQMYNLLLSYDEH 225
C EIV+LL+E+ DI +QDS GN +LH L+ + F +MY+++L +
Sbjct: 155 CTNQPEIVQLLMENEQTDITSQDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILLRSGN 214
Query: 226 SDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQK 262
+ LE + N+ GLTP +LA G + ++++ +
Sbjct: 215 WE----LETMRNNDGLTPLQLAAKMGKAEILKYILSR 247
>5OEO-C nrPDB
Length = 73
Score = 88.2 bits (217), Expect = 1e-17, Method: Composition-based stats.
Identities = 55/73 (75%), Positives = 61/73 (83%), Gaps = 1/73 (1%)
Query: 654 SDKEDGQEQLSEKRPSTVESGMLSRASVAFQTPSLSRTTSQSSNSHRGWEILRRNTLGHL 713
+DKED QE SEK+PS ESG L+RAS+A T SLSRT SQSS SHRGWEILR+NTLGHL
Sbjct: 2 ADKEDDQEHPSEKQPSGAESGTLARASLALPTSSLSRTASQSS-SHRGWEILRQNTLGHL 60
Query: 714 NLGLDLGEGDGEE 726
NLGL+L EGDGEE
Sbjct: 61 NLGLNLSEGDGEE 73
>5MIO-C nrPDB
Length = 573
Score = 74.3 bits (181), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 52/164 (31%), Positives = 81/164 (49%), Gaps = 19/164 (11%)
Query: 49 LLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKE 108
LL+AA+ +++L+ N D A G T LH+AA Y +LE +L++ +++
Sbjct: 414 LLEAARAGQDDEVRVLMAN-GADVNATDASGLTPLHLAATYGHLEIVEVLLKHGADVS-- 470
Query: 109 PALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLS 168
+G T LH+A + +L +V LL GA V+A T +G+ PL
Sbjct: 471 ---ASDLMGSTPLHLAALIGHLEIVEVLLKHGADVNAVDT-------------WGDTPLR 514
Query: 169 FAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFA 212
AA +G +IV L++HGAD+ AQD G T I ++ A
Sbjct: 515 LAAVMGHLKIVEALLKHGADVNAQDKFGKTAYDTSIDNGSEDLA 558
Score = 56.2 bits (134), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 54/176 (30%), Positives = 85/176 (48%), Gaps = 27/176 (15%)
Query: 116 VGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGS 175
+G+ L A Q+ + VR L+A GA V+A T A+ G PL AA G
Sbjct: 410 LGKKLLEAARAGQD-DEVRVLMANGADVNA--TDAS-----------GLTPLHLAATYGH 455
Query: 176 EEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELV 235
EIV +L++HGAD+ A D +G+T LH+ L + ++ +LL + + + +
Sbjct: 456 LEIVEVLLKHGADVSASDLMGSTPLHLAALIGH----LEIVEVLLKHGADVNAVDTW--- 508
Query: 236 PNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSWGEELS 291
G TP +LA V G+ + + L++ V T YD T ID+ E+L+
Sbjct: 509 ----GDTPLRLAAVMGHLKIVEALLKHGADVNAQ-DKFGKTAYD-TSIDNGSEDLA 558
>6MWQ-A nrPDB
Length = 493
Score = 70.5 bits (171), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 58/177 (32%), Positives = 81/177 (45%), Gaps = 19/177 (10%)
Query: 49 LLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKE 108
LL+AA+ ++IL+ N D G T LH+AA +LE +L++ ++
Sbjct: 9 LLEAARAGQDDEVRILMAN-GADVNALDRFGLTPLHLAAQRGHLEIVEVLLKCGADVN-- 65
Query: 109 PALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLS 168
GQT LH+A +L +V LL GA V+A L G+ PL
Sbjct: 66 ---AADLWGQTPLHLAATAGHLEIVEVLLKYGADVNA-------------LDLIGKTPLH 109
Query: 169 FAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEH 225
A G EIV +L++HGAD+ AQD G T I I N+ A + L LS H
Sbjct: 110 LTAIDGHLEIVEVLLKHGADVNAQDKFGKTAFDISIDNGNEDLAEILQKLNLSDIAH 166
>5H76-A nrPDB
Length = 201
Score = 64.3 bits (155), Expect = 2e-10, Method: Composition-based stats.
Identities = 59/198 (29%), Positives = 90/198 (45%), Gaps = 26/198 (13%)
Query: 49 LLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKE 108
LL+AA+ ++IL+ N + D G T LH+AA +LE +L++ ++
Sbjct: 10 LLEAARAGQDDEVRILMANGA-DVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVDAS 68
Query: 109 PALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLS 168
G T LH+A +L +V LL GA V+A + G PL
Sbjct: 69 DVF-----GYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSD-------------GMTPLH 110
Query: 169 FAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFA--CQMYNLL----LSY 222
AA G EIV +L++HGA + AQD G T I I N+ A Y +L L+
Sbjct: 111 LAAKWGYLEIVEVLLKHGA-VNAQDKFGKTAFDISIDNGNEDLAQILAFYEILHLPNLNE 169
Query: 223 DEHSDHLQSLELVPNHQG 240
++ + +QSL+ P+
Sbjct: 170 EQRNAFIQSLKDDPSQSA 187
Score = 46.2 bits (108), Expect = 5e-05, Method: Composition-based stats.
Identities = 32/87 (36%), Positives = 43/87 (49%), Gaps = 14/87 (16%)
Query: 116 VGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGS 175
+G+ L A Q+ + VR L+A GA V+A G PL AA G
Sbjct: 6 LGRKLLEAARAGQD-DEVRILMANGADVNAADNT-------------GTTPLHLAAYSGH 51
Query: 176 EEIVRLLIEHGADIRAQDSLGNTVLHI 202
EIV +L++HGAD+ A D G T LH+
Sbjct: 52 LEIVEVLLKHGADVDASDVFGYTPLHL 78
>6FES-A nrPDB
Length = 367
Score = 63.2 bits (152), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 50/152 (32%), Positives = 69/152 (45%), Gaps = 19/152 (12%)
Query: 47 SPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELA 106
LL+AA+ ++ILL N D G T LH+AA +L +L++ ++
Sbjct: 8 KKLLEAARAGQDDEVRILLAN-GADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADVN 66
Query: 107 KEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHP 166
G T LH+A +L +V LL GA V+A G P
Sbjct: 67 -----ANDERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATDV-------------IGTAP 108
Query: 167 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNT 198
L AA G EEIV +L+++GAD RAQD G T
Sbjct: 109 LHLAAMWGHEEIVEVLLKNGADARAQDKFGKT 140
Score = 45.8 bits (107), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 13/86 (15%)
Query: 117 GQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSE 176
G T LH+A +L +V LL GA V+A G PL AA G
Sbjct: 39 GFTPLHLAAWEGHLGIVEVLLKNGADVNANDE-------------RGHTPLHLAAYTGHL 85
Query: 177 EIVRLLIEHGADIRAQDSLGNTVLHI 202
EIV +L+++GA + A D +G LH+
Sbjct: 86 EIVEVLLKNGAGVNATDVIGTAPLHL 111
Score = 39.7 bits (91), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 32/88 (36%), Positives = 44/88 (50%), Gaps = 16/88 (18%)
Query: 116 VGQTALHIAVMNQNLNLVRALLARGASV-SARATGAAFRRSPHNLIYYGEHPLSFAACVG 174
+G+ L A Q+ + VR LLA GA V +A TG PL AA G
Sbjct: 6 LGKKLLEAARAGQD-DEVRILLANGADVNTADETGFT--------------PLHLAAWEG 50
Query: 175 SEEIVRLLIEHGADIRAQDSLGNTVLHI 202
IV +L+++GAD+ A D G+T LH+
Sbjct: 51 HLGIVEVLLKNGADVNANDERGHTPLHL 78
>5AQA-A nrPDB
Length = 418
Score = 60.1 bits (144), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 50/167 (29%), Positives = 76/167 (45%), Gaps = 19/167 (11%)
Query: 49 LLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKE 108
LL+AA+ ++IL+ N D G T LH+AA +LE +L++ ++
Sbjct: 18 LLEAARAGQDDEVRILMAN-GADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVD-- 74
Query: 109 PALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLS 168
G T LH+A +L +V LL GA V+A + G PL
Sbjct: 75 ---ASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNA-------------MDSDGMTPLH 118
Query: 169 FAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQM 215
AA G +EIV +L++ GAD+ AQD G L + Q + A ++
Sbjct: 119 LAAKWGYKEIVEVLLKAGADVDAQDKFGKRPLWLAADQGHAEIAAKL 165
Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 32/87 (36%), Positives = 43/87 (49%), Gaps = 14/87 (16%)
Query: 116 VGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGS 175
+G+ L A Q+ + VR L+A GA V+A G PL AA G
Sbjct: 14 LGRKLLEAARAGQD-DEVRILMANGADVNAADN-------------TGTTPLHLAAYSGH 59
Query: 176 EEIVRLLIEHGADIRAQDSLGNTVLHI 202
EIV +L++HGAD+ A D G T LH+
Sbjct: 60 LEIVEVLLKHGADVDASDVFGYTPLHL 86
>5AQB-A nrPDB
Length = 428
Score = 59.3 bits (142), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 52/164 (31%), Positives = 75/164 (45%), Gaps = 20/164 (12%)
Query: 49 LLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKE 108
LL+AA+ +IL+ N D VG T LH+AA + +LE L++ ++
Sbjct: 18 LLEAARAGQDDECRILMAN-GADVNALDEVGWTPLHLAA-WGHLEIVECLLKNGADVN-- 73
Query: 109 PALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLS 168
G T LH+A + +L +V LL GA V+A G PL
Sbjct: 74 ---AADIDGYTPLHLAAFSGHLEIVEVLLKYGADVNADD-------------QAGFTPLH 117
Query: 169 FAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFA 212
AA G EIV +L+++GAD+ AQD G T + I N+ A
Sbjct: 118 LAAIFGHLEIVEVLLKNGADVNAQDKFGKTPRDLAIDNGNEDIA 161
>5AQ7-A nrPDB
Length = 418
Score = 58.5 bits (140), Expect = 9e-09, Method: Compositional matrix adjust.
Identities = 50/167 (29%), Positives = 74/167 (44%), Gaps = 19/167 (11%)
Query: 49 LLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKE 108
LL+AA+ ++ILL N D G T LH+AA +L +L++ ++
Sbjct: 18 LLEAARAGQDDEVRILLAN-GADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADVN-- 74
Query: 109 PALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLS 168
G T LH+A +L +V LL GA V+A G PL
Sbjct: 75 ---ANDERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATDV-------------IGTAPLH 118
Query: 169 FAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQM 215
AA G +EIV +L++ GAD+ AQD G L + Q + A ++
Sbjct: 119 LAAMWGYKEIVEVLLKAGADVDAQDKFGKRPLWLAADQGHAEIAAKL 165
Score = 38.1 bits (87), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 32/88 (36%), Positives = 44/88 (50%), Gaps = 16/88 (18%)
Query: 116 VGQTALHIAVMNQNLNLVRALLARGASV-SARATGAAFRRSPHNLIYYGEHPLSFAACVG 174
+G+ L A Q+ + VR LLA GA V +A TG PL AA G
Sbjct: 14 LGKKLLEAARAGQD-DEVRILLANGADVNTADETGFT--------------PLHLAAWEG 58
Query: 175 SEEIVRLLIEHGADIRAQDSLGNTVLHI 202
IV +L+++GAD+ A D G+T LH+
Sbjct: 59 HLGIVEVLLKNGADVNANDERGHTPLHL 86
>5AQ9-A nrPDB
Length = 422
Score = 52.8 bits (125), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 44/137 (32%), Positives = 60/137 (43%), Gaps = 24/137 (17%)
Query: 116 VGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGS 175
G T LH+A + +L +V LL GA V A +G PL AA G
Sbjct: 46 TGTTPLHLAAYSGHLEIVEVLLKHGADVDASDV-------------FGYTPLHLAAYWGH 92
Query: 176 EEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELV 235
EIV +L+++GAD+ A DS G T LH+ K ++ +LL + +
Sbjct: 93 LEIVEVLLKNGADVNAMDSDGMTPLHLAA----KWGYLEIVEVLLKHGADVNAQDKF--- 145
Query: 236 PNHQGLTPFKLAGVEGN 252
G TPF LA GN
Sbjct: 146 ----GKTPFDLADDNGN 158
Score = 45.8 bits (107), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 49/190 (25%), Positives = 81/190 (42%), Gaps = 26/190 (13%)
Query: 116 VGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGS 175
+G+ L A Q+ + VR L+A GA V+A G PL AA G
Sbjct: 14 LGRKLLEAARAGQD-DEVRILMANGADVNAADN-------------TGTTPLHLAAYSGH 59
Query: 176 EEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELV 235
EIV +L++HGAD+ A D G T LH+ + ++ +LL + + S
Sbjct: 60 LEIVEVLLKHGADVDASDVFGYTPLHLAAYWGH----LEIVEVLLKNGADVNAMDS---- 111
Query: 236 PNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSWGEELSFLEL 295
G+TP LA G + + L++ V T +DL + + + + L++
Sbjct: 112 ---DGMTPLHLAAKWGYLEIVEVLLKHGADVN-AQDKFGKTPFDLADDNGNDDVGTLLQV 167
Query: 296 VVSSKKREAR 305
++ + AR
Sbjct: 168 AAAADQLGAR 177
>6AUN-A nrPDB
Length = 752
Score = 51.2 bits (121), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 67/241 (27%), Positives = 102/241 (42%), Gaps = 51/241 (21%)
Query: 47 SPLLQAAKENDLRLLKILLLNQSCDFQQ--RGAVGETALHVAALYDNLEAATLLMEAAP- 103
+PL A ++ D +L L+ Q C Q GETA H A DN + LL + A
Sbjct: 154 TPLHLACRKGDSEILVELV--QYCHAQMDVTDNKGETAFHYAVQGDNSQVLQLLGKNASA 211
Query: 104 ---ELAKEPALCEPFVGQTALHIAVMNQNLNLVRALL---AR----GASVSARATGAAF- 152
++ K+ G T LH+A +VR LL AR G S T F
Sbjct: 212 GLNQVNKQ--------GLTPLHLACQMGKQEMVRVLLLCNARCNVMGPSGFPIHTAMKFS 263
Query: 153 RRSPHNLIY-------------YGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTV 199
++ +I YG PL +A + E+ R+L++ G D+ + + GNT
Sbjct: 264 QKGCAEMIISMDSSQIHSKDPRYGASPLHWAK---NAEMARMLLKRGCDVDSTSAAGNTA 320
Query: 200 LHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHL 259
LH+ +++ F C M +LL+Y ++ P G TP LA + N M + L
Sbjct: 321 LHVAVMR--NRFDCVM--VLLTYGANAG-------TPGEHGNTPLHLAISKDNMEMIKAL 369
Query: 260 M 260
+
Sbjct: 370 I 370
Score = 46.6 bits (109), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 26/80 (32%), Positives = 40/80 (50%), Gaps = 5/80 (6%)
Query: 64 LLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHI 123
+LL + CD A G TALHVA + + + +L+ A P G T LH+
Sbjct: 302 MLLKRGCDVDSTSAAGNTALHVAVMRNRFDCVMVLLTYGAN-AGTPGEH----GNTPLHL 356
Query: 124 AVMNQNLNLVRALLARGASV 143
A+ N+ +++AL+ GA V
Sbjct: 357 AISKDNMEMIKALIVFGAEV 376
Score = 41.2 bits (95), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 33/120 (27%), Positives = 50/120 (41%), Gaps = 21/120 (17%)
Query: 79 GETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLA 138
G + LH A N E A +L++ ++ A G TALH+AVM + V LL
Sbjct: 287 GASPLHWAK---NAEMARMLLKRGCDVDSTSA-----AGNTALHVAVMRNRFDCVMVLLT 338
Query: 139 RGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNT 198
GA+ +G PL A + E+++ LI GA++ + G T
Sbjct: 339 YGANAGTPGE-------------HGNTPLHLAISKDNMEMIKALIVFGAEVDTPNDFGET 385
>4Z68-A nrPDB
Length = 155
Score = 49.7 bits (117), Expect = 4e-06, Method: Composition-based stats.
Identities = 45/159 (28%), Positives = 69/159 (43%), Gaps = 20/159 (12%)
Query: 46 DSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPEL 105
D LL+AAK D+ +K L QS + + T LH AA Y+ + L++ ++
Sbjct: 4 DRQLLEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADV 63
Query: 106 -AKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGE 164
AK+ G LH A + + L+ GA V+ +
Sbjct: 64 HAKDKG------GLVPLHNACSYGHYEVAELLVKHGAVVNVAD-------------LWKF 104
Query: 165 HPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHIL 203
PL AA G EI +LL++HGAD ++ GNT L ++
Sbjct: 105 TPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLV 143
>5CBO-A nrPDB
Length = 176
Score = 48.1 bits (113), Expect = 1e-05, Method: Composition-based stats.
Identities = 33/96 (34%), Positives = 44/96 (45%), Gaps = 13/96 (13%)
Query: 117 GQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSE 176
G T LH+A + +V LL GA V+A G+ PL AA G
Sbjct: 36 GVTPLHLAAYWGHFEIVEVLLKYGADVNASDAT-------------GDTPLHLAAKWGYL 82
Query: 177 EIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFA 212
IV +L+++GAD+ AQD G T I I N+ A
Sbjct: 83 GIVEVLLKYGADVNAQDKFGKTAFDISIDNGNEDLA 118
Score = 46.6 bits (109), Expect = 4e-05, Method: Composition-based stats.
Identities = 31/87 (35%), Positives = 46/87 (52%), Gaps = 14/87 (16%)
Query: 116 VGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGS 175
+G+ L A Q+ + VR L+A GA V+A +G PL AA G
Sbjct: 3 LGKKLLEAAHAGQD-DEVRILMANGADVNAMDN-------------FGVTPLHLAAYWGH 48
Query: 176 EEIVRLLIEHGADIRAQDSLGNTVLHI 202
EIV +L+++GAD+ A D+ G+T LH+
Sbjct: 49 FEIVEVLLKYGADVNASDATGDTPLHL 75
Score = 33.1 bits (74), Expect = 0.39, Method: Composition-based stats.
Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 6/99 (6%)
Query: 47 SPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELA 106
+PL AA ++++LL D A G+T LH+AA + L +L++ ++
Sbjct: 38 TPLHLAAYWGHFEIVEVLL-KYGADVNASDATGDTPLHLAAKWGYLGIVEVLLKYGADVN 96
Query: 107 KEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSA 145
+ G+TA I++ N N +L L A +A
Sbjct: 97 AQDKF-----GKTAFDISIDNGNEDLAEILCKNKAQQAA 130
>5GP7-A nrPDB
Length = 169
Score = 44.7 bits (104), Expect = 1e-04, Method: Composition-based stats.
Identities = 42/157 (26%), Positives = 68/157 (43%), Gaps = 18/157 (11%)
Query: 46 DSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPEL 105
D+ LL AAK+ L ++ L ++ + + T LH+AA Y+NLE A L+E ++
Sbjct: 10 DAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADV 69
Query: 106 AKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEH 165
+ G LH A ++++ L+ V+A A
Sbjct: 70 NAQDK-----GGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAF-------------T 111
Query: 166 PLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHI 202
PL AA G ++ LL+ HGAD ++ G T L +
Sbjct: 112 PLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDL 148
>4OAU-C nrPDB
Length = 699
Score = 43.5 bits (101), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 53/205 (25%), Positives = 94/205 (45%), Gaps = 17/205 (8%)
Query: 64 LLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHI 123
LLL D R G T +AA+ +++ L + ++ + C+ F G TA
Sbjct: 57 LLLRHGADPVLRKKNGATPFILAAIAGSVKLLKLFLSKGADVNE----CD-FYGFTAFME 111
Query: 124 AVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLI 183
A + + ++ L RGA+V+ R + L G L AA G E++++L+
Sbjct: 112 AAVYGKVKALKFLYKRGANVNLRRKT---KEDQERLRKGGATALMDAAEKGHVEVLKILL 168
Query: 184 -EHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQGLT 242
E GAD+ A D++G L +L + + + +LLL DH + V +G T
Sbjct: 169 DEMGADVNACDNMGRNALIHALLSSDDSDVEAITHLLL------DHGADVN-VRGERGKT 221
Query: 243 PFKLAGVEGNTVMFQHLMQKRKHVQ 267
P LA + + + Q L++ ++H++
Sbjct: 222 PLILAVEKKHLGLVQRLLE-QEHIE 245
Score = 36.2 bits (82), Expect = 0.058, Method: Compositional matrix adjust.
Identities = 45/160 (28%), Positives = 69/160 (43%), Gaps = 16/160 (10%)
Query: 47 SPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPEL- 105
+P + AA ++LLK L L++ D + G TA AA+Y ++A L + +
Sbjct: 74 TPFILAAIAGSVKLLK-LFLSKGADVNECDFYGFTAFMEAAVYGKVKALKFLYKRGANVN 132
Query: 106 ----AKEPALCEPFVGQTALHIAVMNQNLNLVRALLAR-GASVSARATGAAFRRSPHNLI 160
KE G TAL A ++ +++ LL GA V+A + LI
Sbjct: 133 LRRKTKEDQERLRKGGATALMDAAEKGHVEVLKILLDEMGADVNA-----CDNMGRNALI 187
Query: 161 YYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVL 200
H L + E I LL++HGAD+ + G T L
Sbjct: 188 ----HALLSSDDSDVEAITHLLLDHGADVNVRGERGKTPL 223
Score = 35.4 bits (80), Expect = 0.089, Method: Compositional matrix adjust.
Identities = 22/65 (33%), Positives = 34/65 (52%), Gaps = 12/65 (18%)
Query: 124 AVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLI 183
AV N++++LV+ LL GA+V+ + + PL A + E+IV LL+
Sbjct: 12 AVQNEDVDLVQQLLEGGANVNFQEEEGGWT------------PLHNAVQMSREDIVELLL 59
Query: 184 EHGAD 188
HGAD
Sbjct: 60 RHGAD 64
>6G1K-A nrPDB
Length = 921
Score = 43.1 bits (100), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 34/136 (25%), Positives = 68/136 (50%), Gaps = 17/136 (12%)
Query: 475 LGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFH-ITFQTEDPNNL---GEFSDYPTAL 530
LGP I + +M+ D+++F ++ +V+L FA+ + + F E+ + G +
Sbjct: 502 LGPLQISLGRMLL-DILKFLFIYCLVLLAFANGLNQLYFYYENSEGMTCKGIRCERQNNA 560
Query: 531 FST-FE----LFLTIIDGPANYSVDLP-------FMYCITYAAFAIIATLLMLNLFIAMM 578
FST FE LF +I + Y ++ F+ + + +I+ +++LN+ IAMM
Sbjct: 561 FSTLFETLQSLFWSIFGLISLYVTNVKADHKFTEFVGATMFGTYNVISLVVLLNMLIAMM 620
Query: 579 GDTHWRVAQERDELWR 594
+++ +A D W+
Sbjct: 621 NNSYQHIADHADIEWK 636
>5Z96-A nrPDB
Length = 755
Score = 43.1 bits (100), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 32/136 (23%), Positives = 65/136 (47%), Gaps = 17/136 (12%)
Query: 475 LGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFH-ITFQTEDPNNLG-------EFSDY 526
LGP I + +M+ D+++F ++ +V+L FA+ + + F E+ L + ++
Sbjct: 502 LGPLQISLGRMLL-DILKFLFIYCLVLLAFANGLNQLYFYYEETKGLSCKGIRCEKQNNA 560
Query: 527 PTALFSTFELFLTIIDGPANYSVD--------LPFMYCITYAAFAIIATLLMLNLFIAMM 578
+ LF T + I G N V F+ + + +I+ +++LN+ IAMM
Sbjct: 561 FSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMM 620
Query: 579 GDTHWRVAQERDELWR 594
+++ +A D W+
Sbjct: 621 NNSYQLIADHADIEWK 636
>3B7B-A nrPDB
Length = 237
Score = 42.0 bits (97), Expect = 0.001, Method: Composition-based stats.
Identities = 46/173 (26%), Positives = 77/173 (44%), Gaps = 32/173 (18%)
Query: 36 VNMLQQERIRDSPLLQAAKENDLRLLKILLLN----QSCDFQQRGAVGETALHVAALYDN 91
+N + + + SPL AA+ + + +L+ +C QR T L AA ++
Sbjct: 2 MNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANIDTCSEDQR-----TPLMEAAENNH 56
Query: 92 LEAATLLMEAAPELAKEPALCEP--FVGQTALHIAVMNQNLNLVRALLARGA-SVSARAT 148
LEA L++A AL +P G T LH+A + +V+ LL+ G V+ +
Sbjct: 57 LEAVKYLIKAG-------ALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDD 109
Query: 149 GAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLH 201
G G P+ +A ++V+LL+ G+DI +D+ N LH
Sbjct: 110 G-------------GWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLH 149
Score = 30.4 bits (67), Expect = 2.9, Method: Composition-based stats.
Identities = 26/100 (26%), Positives = 45/100 (45%), Gaps = 6/100 (6%)
Query: 47 SPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELA 106
+P++ A + + L+K LLL++ D R LH AA ++ A +L+ A +L
Sbjct: 113 TPMIWATEYKHVDLVK-LLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLAAKCDLH 171
Query: 107 KEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSAR 146
G + LHIA + V L+R + V+ +
Sbjct: 172 -----AVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLK 206
>4OT9-A nrPDB
Length = 359
Score = 41.2 bits (95), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 28/78 (35%), Positives = 42/78 (53%), Gaps = 14/78 (17%)
Query: 117 GQTALHIAVMNQNLNLVRALLAR-GASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGS 175
G+TALH+A + L LV L+ + A+V+AR + G PL AA +G
Sbjct: 228 GRTALHLATEMEELGLVTHLVTKLRANVNAR-------------TFAGNTPLHLAAGLGY 274
Query: 176 EEIVRLLIEHGADIRAQD 193
+ RLL++ GADI A++
Sbjct: 275 PTLTRLLLKAGADIHAEN 292
Score = 33.1 bits (74), Expect = 0.41, Method: Compositional matrix adjust.
Identities = 35/126 (27%), Positives = 59/126 (46%), Gaps = 16/126 (12%)
Query: 80 ETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQN--LNLVRALL 137
+T LH+A + + L+ + +PAL + G +A+H+A+ L+RALL
Sbjct: 122 QTPLHLAVITGQTSVVSFLLR----VGADPALLDRH-GDSAMHLALRAGAGAPELLRALL 176
Query: 138 ARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGN 197
GA A + H + G +P+ A S E + LL++ GA++ A + G
Sbjct: 177 QSGAP--------AVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGG 228
Query: 198 -TVLHI 202
T LH+
Sbjct: 229 RTALHL 234
Score = 28.9 bits (63), Expect = 9.3, Method: Compositional matrix adjust.
Identities = 34/126 (26%), Positives = 54/126 (42%), Gaps = 16/126 (12%)
Query: 136 LLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSL 195
+L R +AR G A +RS L+ YG + A G + + AQD
Sbjct: 33 MLQRAREYNARLFGLA-QRSARALLDYGVTADARALLAGQRHL----------LTAQDEN 81
Query: 196 GNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQGLTPFKLAGVEGNTVM 255
G+T LH+ I+ + Q+ ++ H+ L + L NH TP LA + G T +
Sbjct: 82 GDTPLHLAIIHGQTSVIEQIVYVI----HHAQDLGVVNLT-NHLHQTPLHLAVITGQTSV 136
Query: 256 FQHLMQ 261
L++
Sbjct: 137 VSFLLR 142
>6BY9-A nrPDB
Length = 328
Score = 38.9 bits (89), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 46/172 (26%), Positives = 76/172 (44%), Gaps = 32/172 (18%)
Query: 37 NMLQQERIRDSPLLQAAKENDLRLLKILLLN----QSCDFQQRGAVGETALHVAALYDNL 92
N + + + SPL AA+ + + +L+ +C QR T L AA ++L
Sbjct: 94 NFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANIDTCSEDQR-----TPLMEAAENNHL 148
Query: 93 EAATLLMEAAPELAKEPALCEP--FVGQTALHIAVMNQNLNLVRALLARGA-SVSARATG 149
EA L++A AL +P G T LH+A + +V+ LL+ G V+ + G
Sbjct: 149 EAVKYLIKAG-------ALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDG 201
Query: 150 AAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLH 201
G P+ +A ++V+LL+ G+DI +D+ N LH
Sbjct: 202 -------------GWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLH 240
>5HKP-A nrPDB
Length = 351
Score = 38.9 bits (89), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 36/113 (31%), Positives = 53/113 (46%), Gaps = 20/113 (17%)
Query: 113 EPFVGQTALHIAVMN---QNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSF 169
+P +TALH AV + + + LL +GA+V+ + N + PL
Sbjct: 207 QPQSHETALHCAVASLHPKRKQVAELLLRKGANVNEK-----------NKDFMT--PLHV 253
Query: 170 AACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSY 222
AA +++ +L +HGA + A DSLG T LH L + Q LLLSY
Sbjct: 254 AAERAHNDVMEVLHKHGAKMNALDSLGQTALHRAALAGH----LQTCRLLLSY 302
Score = 35.8 bits (81), Expect = 0.071, Method: Compositional matrix adjust.
Identities = 43/143 (30%), Positives = 70/143 (48%), Gaps = 22/143 (15%)
Query: 49 LLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALH--VAALY-DNLEAATLLMEAAPEL 105
LLQAA+E DL +K L + +F+Q + ETALH VA+L+ + A LL+ +
Sbjct: 182 LLQAAREADLAKVKKTLALEIINFKQPQS-HETALHCAVASLHPKRKQVAELLLRKGANV 240
Query: 106 AKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEH 165
++ + F+ T LH+A + +++ L GA ++A L G+
Sbjct: 241 NEKN---KDFM--TPLHVAAERAHNDVMEVLHKHGAKMNA-------------LDSLGQT 282
Query: 166 PLSFAACVGSEEIVRLLIEHGAD 188
L AA G + RLL+ +G+D
Sbjct: 283 ALHRAALAGHLQTCRLLLSYGSD 305
Score = 34.7 bits (78), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 17/36 (47%), Positives = 22/36 (61%)
Query: 166 PLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLH 201
PL AA IV+LL++HGAD+ A+D G LH
Sbjct: 61 PLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLH 96
>4NIK-A nrPDB
Length = 230
Score = 38.9 bits (89), Expect = 0.009, Method: Composition-based stats.
Identities = 38/143 (26%), Positives = 61/143 (42%), Gaps = 27/143 (18%)
Query: 81 TALHVAALYDNLEAATLLME-AAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLAR 139
TALH A + E L++ P K+ A G + LHIA +V+ALL +
Sbjct: 46 TALHWACSAGHTEIVEFLLQLGVPVNDKDDA------GWSPLHIAASAGRDEIVKALLGK 99
Query: 140 GASVSARATGA------AFRRSPHNLI--------------YYGEHPLSFAACVGSEEIV 179
GA V+A A ++ H + +Y + AA G+ +++
Sbjct: 100 GAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMI 159
Query: 180 RLLIEHGADIRAQDSLGNTVLHI 202
+L+ + A QD+ GNT LH+
Sbjct: 160 HILLYYKASTNIQDTEGNTPLHL 182
Score = 36.6 bits (83), Expect = 0.039, Method: Composition-based stats.
Identities = 27/84 (32%), Positives = 37/84 (44%), Gaps = 13/84 (15%)
Query: 118 QTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEE 177
+TALH A + +V LL G V+ + G PL AA G +E
Sbjct: 45 RTALHWACSAGHTEIVEFLLQLGVPVNDKDDA-------------GWSPLHIAASAGRDE 91
Query: 178 IVRLLIEHGADIRAQDSLGNTVLH 201
IV+ L+ GA + A + G T LH
Sbjct: 92 IVKALLGKGAQVNAVNQNGCTPLH 115
Score = 36.2 bits (82), Expect = 0.057, Method: Composition-based stats.
Identities = 45/158 (28%), Positives = 63/158 (39%), Gaps = 23/158 (14%)
Query: 47 SPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLME--AAPE 104
SPL AA ++K LL + G T LH AA + E A +L+E A P+
Sbjct: 79 SPLHIAASAGRDEIVKALL-GKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPD 137
Query: 105 LAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGE 164
AK+ TA+H A NL ++ LL AS + + T G
Sbjct: 138 -AKD------HYEATAMHRAAAKGNLKMIHILLYYKASTNIQDT-------------EGN 177
Query: 165 HPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHI 202
PL A E +LL+ GA I ++ T L +
Sbjct: 178 TPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQV 215
>1BLX-B nrPDB
Length = 166
Score = 38.1 bits (87), Expect = 0.015, Method: Compositional matrix adjust.
Identities = 28/97 (28%), Positives = 46/97 (47%), Gaps = 12/97 (12%)
Query: 155 SPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQ 214
SP+ G P+ AA G + +++L+EHGAD+ A DS G+ +H+ I + + +
Sbjct: 66 SPNVQDASGTSPVHDAARTGFLDTLKVLVEHGADVNALDSTGSLPIHLAIREGHSSVVS- 124
Query: 215 MYNLLLSYDEHSDHLQSLELVPNHQGLTPFKLAGVEG 251
L+ + H + GLTP +LA G
Sbjct: 125 ----FLAPESDLHHRDA-------SGLTPLELARQRG 150
>4O1O-A nrPDB
Length = 717
Score = 38.1 bits (87), Expect = 0.015, Method: Compositional matrix adjust.
Identities = 48/168 (28%), Positives = 74/168 (44%), Gaps = 16/168 (9%)
Query: 47 SPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPEL- 105
+P + A ++RLL++LL N D + G TA AA+Y +EA L E ++
Sbjct: 77 TPFIIAGITGNVRLLQLLLPNVE-DVNECDVNGFTAFMEAAVYGRVEALRFLYENGADVN 135
Query: 106 ----AKEPALCEPFVGQTALHIAVMNQNLNLVRALL-ARGASVSARATGAAFRRSPHNLI 160
K+ G TAL A ++ +V LL A A V AR + L+
Sbjct: 136 MHRKTKQDQERIRKGGATALMDAAEKGHVGVVTILLHAMKAEVDARDN-----MGRNALV 190
Query: 161 YYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPN 208
Y +P A + I RLL++HGAD+ + T L + + + N
Sbjct: 191 YALLNPDDGKA----KAITRLLLDHGADVNVRGEGSKTPLILAVERKN 234
Score = 36.2 bits (82), Expect = 0.048, Method: Compositional matrix adjust.
Identities = 29/83 (34%), Positives = 40/83 (48%), Gaps = 17/83 (20%)
Query: 106 AKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEH 165
A +PA E + Q AV ++ VR LL RGA A F+ +G
Sbjct: 2 AMDPASLEEMLTQ-----AVQEADIEQVRQLLERGAD-------ANFQEEE-----WGWS 44
Query: 166 PLSFAACVGSEEIVRLLIEHGAD 188
PL A + SE++V LL++HGAD
Sbjct: 45 PLHSAVQMDSEDLVALLLKHGAD 67
Score = 35.0 bits (79), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 68/259 (26%), Positives = 108/259 (41%), Gaps = 25/259 (9%)
Query: 13 AQLQKLLISWPVGEQDWEQYRDRVNM-----LQQERIRDSPLLQAAKENDLRLLKILLLN 67
A L+++L + V E D EQ R + Q+E SPL +A + D L LLL
Sbjct: 6 ASLEEML-TQAVQEADIEQVRQLLERGADANFQEEEWGWSPL-HSAVQMDSEDLVALLLK 63
Query: 68 QSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMN 127
D R G T +A + N+ LL+ ++ + C+ G TA A +
Sbjct: 64 HGADPCLRKRNGATPFIIAGITGNVRLLQLLLPNVEDVNE----CD-VNGFTAFMEAAVY 118
Query: 128 QNLNLVRALLARGASVSA-RATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEH- 185
+ +R L GA V+ R T ++ + G L AA G +V +L+
Sbjct: 119 GRVEALRFLYENGADVNMHRKT----KQDQERIRKGGATALMDAAEKGHVGVVTILLHAM 174
Query: 186 GADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQGLTPFK 245
A++ A+D++G L +L P+ A + LLL DH + V TP
Sbjct: 175 KAEVDARDNMGRNALVYALLNPDDGKAKAITRLLL------DHGADVN-VRGEGSKTPLI 227
Query: 246 LAGVEGNTVMFQHLMQKRK 264
LA N + Q L+++ +
Sbjct: 228 LAVERKNLDLVQMLLEQEQ 246
>3EU9-A nrPDB
Length = 240
Score = 37.7 bits (86), Expect = 0.016, Method: Compositional matrix adjust.
Identities = 43/179 (24%), Positives = 75/179 (41%), Gaps = 27/179 (15%)
Query: 52 AAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKEPAL 111
AA N + L+K + + Q G + T LH A +L LM+ +P+L
Sbjct: 49 AAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMK----YGADPSL 104
Query: 112 CEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATG-------AAFRR---SPHNLI- 160
+ G + +H+A + ++V L+A+G V AA+R P L+
Sbjct: 105 IDGE-GCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLL 163
Query: 161 -----------YYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPN 208
Y+ L +A G+ ++ LL+E GA++ AQ+ G + L + + N
Sbjct: 164 TFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGANVDAQNIKGESALDLAKQRKN 222
Score = 33.9 bits (76), Expect = 0.25, Method: Compositional matrix adjust.
Identities = 42/171 (24%), Positives = 67/171 (39%), Gaps = 34/171 (19%)
Query: 119 TALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHN-------------LIYYGEH 165
T LH A +N ++LV+ +++GA V G +P + L+ YG
Sbjct: 44 TLLHWAAINNRIDLVKYYISKGAIVD--QLGGDLNSTPLHWATRQGHLSMVVQLMKYGAD 101
Query: 166 P----------LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQM 215
P + AA G IV LI G D+ D G T L+ +T +
Sbjct: 102 PSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTP---LMWAAYRTHSVDP 158
Query: 216 YNLLLSYDEHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHV 266
LLL+++ S+ L + T A + GNT + L++ +V
Sbjct: 159 TRLLLTFNV------SVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGANV 203
>5JHQ-A nrPDB
Length = 482
Score = 37.7 bits (86), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 57/195 (29%), Positives = 89/195 (45%), Gaps = 37/195 (18%)
Query: 47 SPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATL------LME 100
+PL +AA +N + + LLL+ D G++A+ +A + E T L++
Sbjct: 270 TPLHEAASKNRVEVCS-LLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQ 328
Query: 101 AAPE--LAK-EPALC-------EPFVGQTALHIAVMN---QNLNLVRALLARGASVSARA 147
AA E LAK + L +P +TALH AV + + + LL +GA+V+ +
Sbjct: 329 AAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVTELLLRKGANVNEK- 387
Query: 148 TGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQP 207
N + PL AA +++ +L +HGA + A D+LG T LH L
Sbjct: 388 ----------NKDFMT--PLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAG 435
Query: 208 NKTFACQMYNLLLSY 222
+ Q LLLSY
Sbjct: 436 H----LQTCRLLLSY 446
Score = 35.8 bits (81), Expect = 0.070, Method: Compositional matrix adjust.
Identities = 44/144 (30%), Positives = 66/144 (45%), Gaps = 24/144 (16%)
Query: 49 LLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALH--VAALYDNLEAAT--LLMEAAPE 104
LLQAA+E DL +K L + +F+Q + ETALH VA+L+ + T LL + A
Sbjct: 326 LLQAAREADLAKVKKTLALEIINFKQPQS-HETALHCAVASLHPKRKQVTELLLRKGANV 384
Query: 105 LAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGE 164
K P LH+A + +++ L GA ++A L G+
Sbjct: 385 NEKNKDFMTP------LHVAAERAHNDVMEVLHKHGAKMNA-------------LDTLGQ 425
Query: 165 HPLSFAACVGSEEIVRLLIEHGAD 188
L AA G + RLL+ +G+D
Sbjct: 426 TALHRAALAGHLQTCRLLLSYGSD 449
Score = 34.3 bits (77), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 17/36 (47%), Positives = 22/36 (61%)
Query: 166 PLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLH 201
PL AA IV+LL++HGAD+ A+D G LH
Sbjct: 205 PLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLH 240
Score = 34.3 bits (77), Expect = 0.18, Method: Compositional matrix adjust.
Identities = 28/83 (33%), Positives = 36/83 (43%), Gaps = 13/83 (15%)
Query: 119 TALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEI 178
+ LH A ++V LL GA+V AR G PL A G E+
Sbjct: 51 SPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLI-------------PLHNACSFGHAEV 97
Query: 179 VRLLIEHGADIRAQDSLGNTVLH 201
V LL+ GAD A+D+ T LH
Sbjct: 98 VSLLLCQGADPNARDNWNYTPLH 120
Score = 30.0 bits (66), Expect = 4.1, Method: Compositional matrix adjust.
Identities = 37/153 (24%), Positives = 66/153 (43%), Gaps = 20/153 (13%)
Query: 49 LLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPEL-AK 107
LL+A + D+ +K L+ + + + + LH AA + + L++ + A+
Sbjct: 19 LLEACRNGDVSRVKRLVDAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHAR 78
Query: 108 EPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPL 167
+ G LH A + +V LL +GA +AR N Y PL
Sbjct: 79 DDG------GLIPLHNACSFGHAEVVSLLLCQGADPNAR----------DNWNYT---PL 119
Query: 168 SFAACVGSEEIVRLLIEHGADIRAQDSLGNTVL 200
AA G ++ +L++HGAD +++ G + L
Sbjct: 120 HEAAIKGKIDVCIVLLQHGADPNIRNTDGKSAL 152
>5ET1-A nrPDB
Length = 353
Score = 36.2 bits (82), Expect = 0.049, Method: Compositional matrix adjust.
Identities = 55/201 (27%), Positives = 76/201 (37%), Gaps = 33/201 (16%)
Query: 2 GACP---PKAKGPWAQLQKLLISWPVGEQDWEQYRDRVNMLQQERIRDSPLLQAAKENDL 58
GA P AKG L+ L+ +P G VN Q +PL A +E L
Sbjct: 139 GALPIHYAAAKGDLPSLKLLVGHYPEG----------VNA--QTNNGATPLYLACQEGHL 186
Query: 59 RLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQ 118
+ K L+ S D R G T LH AA + L+ A E + G
Sbjct: 187 EVTKYLVQECSADPHLRAQDGMTPLHAAAQMGHNPVLVWLVSFADVSFSE----QDHDGA 242
Query: 119 TALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEI 178
TA+H A + ++ LL GA +S +G PL AA G E
Sbjct: 243 TAMHFAASRGHTKVLSWLLLHGAEISQD--------------LWGGTPLHDAAENGELEC 288
Query: 179 VRLLIEHGADIRAQDSLGNTV 199
++L +GA + +D G T
Sbjct: 289 CQILAVNGAGLDVRDHDGYTA 309
>1WG0-A nrPDB
Length = 243
Score = 36.2 bits (82), Expect = 0.051, Method: Compositional matrix adjust.
Identities = 37/158 (23%), Positives = 63/158 (39%), Gaps = 13/158 (8%)
Query: 44 IRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAP 103
+ + PL QA EN+ ++ LL ++ Q+ G LH + + E + L+
Sbjct: 1 MSNYPLHQACMENEFFKVQELLHSKPSLLLQKDQDGRIPLHWSVSFQAHEITSFLLSKME 60
Query: 104 ELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYG 163
+ + + G T HIA NL +V++L R + + + G
Sbjct: 61 NVNLDDYPDDS--GWTPFHIACSVGNLEVVKSLYDR-----------PLKPDLNKITNQG 107
Query: 164 EHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLH 201
L A E+ + LIE+GA +R +D LH
Sbjct: 108 VTCLHLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLH 145
>5DND-A nrPDB
Length = 588
Score = 34.7 bits (78), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 35/102 (34%), Positives = 44/102 (43%), Gaps = 18/102 (17%)
Query: 92 LEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAA 151
LEA LME +L + + GQT LH+A N +V LL RG V+AR
Sbjct: 435 LEALQALMELGSDLRLKDS-----NGQTLLHVAARNGRDGVVTMLLHRGMDVNARDRDGL 489
Query: 152 FRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQD 193
SP L G H E +RLL + GA + QD
Sbjct: 490 ---SPLLLAVQGRH----------RECIRLLRKAGACLSPQD 518
Score = 30.8 bits (68), Expect = 2.3, Method: Compositional matrix adjust.
Identities = 14/32 (43%), Positives = 22/32 (68%)
Query: 171 ACVGSEEIVRLLIEHGADIRAQDSLGNTVLHI 202
A G E ++ L+E G+D+R +DS G T+LH+
Sbjct: 430 AHAGELEALQALMELGSDLRLKDSNGQTLLHV 461
>2KXP-C nrPDB
Length = 118
Score = 34.7 bits (78), Expect = 0.15, Method: Composition-based stats.
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 13/70 (18%)
Query: 124 AVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLI 183
A+ N +L+ V+ +A+G V+ G G PL +AA G EI+ L+
Sbjct: 9 ALKNGDLDEVKDYVAKGEDVNRTLEG-------------GRKPLHYAADCGQLEILEFLL 55
Query: 184 EHGADIRAQD 193
GADI A D
Sbjct: 56 LKGADINAPD 65
>6CUD-A nrPDB
Length = 806
Score = 34.7 bits (78), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 33/152 (21%), Positives = 63/152 (41%), Gaps = 20/152 (13%)
Query: 455 SFALVLGWCSVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFHITFQT 514
+ A+VL + + Y + GP I + + + D+ +F L +V F I +
Sbjct: 531 AIAVVLSFSRIAYILPANESFGPLQISLGRTV-KDIFKFMVLFIMVFFAFMIGMFILYSY 589
Query: 515 EDPNNLGEFSDYPTALFSTFE-----LFLTIIDGPANYSVDLPFMY-------CITYAAF 562
LG + A F+T E LF +I SV L + + + Y +
Sbjct: 590 ----YLGAKVN---AAFTTVEESFKTLFWSIFGLSEVTSVVLKYDHKFIENIGYVLYGIY 642
Query: 563 AIIATLLMLNLFIAMMGDTHWRVAQERDELWR 594
+ +++LN+ IAM+ ++ + + D W+
Sbjct: 643 NVTMVVVLLNMLIAMINSSYQEIEDDSDVEWK 674
>2DWZ-A nrPDB
Length = 231
Score = 34.7 bits (78), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 39/143 (27%), Positives = 61/143 (42%), Gaps = 27/143 (18%)
Query: 81 TALHVAALYDNLEAATLLME-AAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLAR 139
TALH A + E L++ P K+ A G + LHIA +V+ALL +
Sbjct: 42 TALHWACSAGHTEIVEFLLQLGVPVNDKDDA------GWSPLHIAASAGRDEIVKALLVK 95
Query: 140 GASVSARATGA------AFRRSPHNLI--------------YYGEHPLSFAACVGSEEIV 179
GA V+A A ++ H + +Y + AA G+ ++V
Sbjct: 96 GAHVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYDATAMHRAAAKGNLKMV 155
Query: 180 RLLIEHGADIRAQDSLGNTVLHI 202
+L+ + A QD+ GNT LH+
Sbjct: 156 HILLFYKASTNIQDTEGNTPLHL 178
Score = 32.7 bits (73), Expect = 0.59, Method: Compositional matrix adjust.
Identities = 27/84 (32%), Positives = 37/84 (44%), Gaps = 13/84 (15%)
Query: 118 QTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEE 177
+TALH A + +V LL G V+ + G PL AA G +E
Sbjct: 41 RTALHWACSAGHTEIVEFLLQLGVPVNDKDDA-------------GWSPLHIAASAGRDE 87
Query: 178 IVRLLIEHGADIRAQDSLGNTVLH 201
IV+ L+ GA + A + G T LH
Sbjct: 88 IVKALLVKGAHVNAVNQNGCTPLH 111
Score = 30.8 bits (68), Expect = 2.0, Method: Compositional matrix adjust.
Identities = 43/158 (27%), Positives = 61/158 (38%), Gaps = 23/158 (14%)
Query: 47 SPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLME--AAPE 104
SPL AA ++K LL+ + G T LH AA + E A +L+E A P+
Sbjct: 75 SPLHIAASAGRDEIVKALLV-KGAHVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPD 133
Query: 105 LAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGE 164
+ TA+H A NL +V LL AS + + T G
Sbjct: 134 -------AKDHYDATAMHRAAAKGNLKMVHILLFYKASTNIQDT-------------EGN 173
Query: 165 HPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHI 202
PL A E + L+ GA I ++ T L +
Sbjct: 174 TPLHLACDEERVEEAKFLVTQGASIYIENKEEKTPLQV 211
Score = 29.3 bits (64), Expect = 6.5, Method: Compositional matrix adjust.
Identities = 28/108 (25%), Positives = 48/108 (44%), Gaps = 8/108 (7%)
Query: 36 VNMLQQERIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAA 95
VN + Q +PL AA +N + ++LL + + TA+H AA NL+
Sbjct: 99 VNAVNQNGC--TPLHYAASKNRHEI-AVMLLEGGANPDAKDHYDATAMHRAAAKGNLKMV 155
Query: 96 TLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASV 143
+L+ K + G T LH+A + + + L+ +GAS+
Sbjct: 156 HILL-----FYKASTNIQDTEGNTPLHLACDEERVEEAKFLVTQGASI 198
>1BD8-A nrPDB
Length = 156
Score = 34.3 bits (77), Expect = 0.20, Method: Compositional matrix adjust.
Identities = 37/131 (28%), Positives = 57/131 (43%), Gaps = 26/131 (19%)
Query: 117 GQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSE 176
G+TAL + +M + + LL +GAS + + T G P+ AA G
Sbjct: 36 GKTALQV-MMFGSTAIALELLKQGASPNVQDT-------------SGTSPVHDAARTGFL 81
Query: 177 EIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVP 236
+ +++L+EHGAD+ D G +H L +Q T L D H
Sbjct: 82 DTLKVLVEHGADVNVPDGTGALPIH-LAVQEGHTAVVSF--LAAESDLHR---------R 129
Query: 237 NHQGLTPFKLA 247
+ +GLTP +LA
Sbjct: 130 DARGLTPLELA 140
>6BWF-A nrPDB
Length = 954
Score = 34.3 bits (77), Expect = 0.20, Method: Compositional matrix adjust.
Identities = 34/154 (22%), Positives = 65/154 (42%), Gaps = 23/154 (14%)
Query: 458 LVLGWCSVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFH-ITFQTED 516
++ + ++ F Q GP+ +MI KM+ ++ +MA+V+L F I + E+
Sbjct: 623 IIFWYVRLLDFLAVNQQAGPYVMMIGKMV-ANMFYIVVIMALVLLSFGVPRKAILYPHEE 681
Query: 517 PN--------------NLGEFSDYPTALFSTFELFLTIIDGPANYSVDLPFMYCITYAAF 562
P+ GE Y + + TI GP + PF+ A +
Sbjct: 682 PSWSLAKDIVFHPYWMIFGEVYAYEIDVCANDSTLPTIC-GPGTWLT--PFLQ----AVY 734
Query: 563 AIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQ 596
+ ++M+NL IA + + +V + +W+ Q
Sbjct: 735 LFVQYIIMVNLLIAFFNNVYLQVKAISNIVWKYQ 768
>3ZKJ-A nrPDB
Length = 261
Score = 33.9 bits (76), Expect = 0.26, Method: Compositional matrix adjust.
Identities = 44/183 (24%), Positives = 76/183 (41%), Gaps = 32/183 (17%)
Query: 36 VNMLQQERIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGE--TALHVAALYDNLE 93
VN++ + + SPL +A L +KILL + + Q G + T L A + + +
Sbjct: 29 VNIITADHV--SPLHEACLGGHLSCVKILLKHGA---QVNGVTADWHTPLFNACVSGSWD 83
Query: 94 AATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSAR------- 146
LL++ + E L P +H A ++ V +L+A G ++ +
Sbjct: 84 CVNLLLQHGASVQPESDLASP------IHEAARRGHVECVNSLIAYGGNIDHKISHLGTP 137
Query: 147 ---ATGAAFRRSPHNLIYYG---------EHPLSFAACVGSEEIVRLLIEHGADIRAQDS 194
A R L+ G + PL A SEE+ LL++ GAD +A+++
Sbjct: 138 LYLACENQQRACVKKLLESGADVNQGKGQDSPLHAVARTASEELACLLMDFGADTQAKNA 197
Query: 195 LGN 197
G
Sbjct: 198 EGK 200
>6CV9-A nrPDB
Length = 842
Score = 33.5 bits (75), Expect = 0.33, Method: Compositional matrix adjust.
Identities = 28/148 (18%), Positives = 63/148 (42%), Gaps = 12/148 (8%)
Query: 455 SFALVLGWCSVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFA-------SA 507
+ A+VL + + Y + GP I + + + D+ +F + +V + F S
Sbjct: 511 AIAVVLSFSRIAYILPANESFGPLQISLGRTV-KDIFKFMVIFIMVFVAFMIGMFNLYSY 569
Query: 508 FHITFQTEDPNNLGE-FSDYPTALFSTFELFLTIIDGPANYSVDLPFMYCITYAAFAIIA 566
+ Q E + E F A+F E+ +I+ + ++ + + Y + +
Sbjct: 570 YIGAKQNEAFTTVEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGY---VLYGVYNVTM 626
Query: 567 TLLMLNLFIAMMGDTHWRVAQERDELWR 594
+++LN+ IAM+ + + + D W+
Sbjct: 627 VIVLLNMLIAMINSSFQEIEDDADVEWK 654
>3EHQ-A nrPDB
Length = 222
Score = 33.5 bits (75), Expect = 0.34, Method: Compositional matrix adjust.
Identities = 35/108 (32%), Positives = 51/108 (47%), Gaps = 8/108 (7%)
Query: 40 QQERIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLM 99
Q E I D+PL +AAK +L L+ L N+ G TAL+ A + + +L
Sbjct: 69 QAESI-DNPLHEAAKRGNLSWLRECLDNR-VGVNGLDKAGSTALYWACHGGHKDIVEMLF 126
Query: 100 -EAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSAR 146
+ EL ++ L G TALH A ++V+ LLA+GA R
Sbjct: 127 TQPNIELNQQNKL-----GDTALHAAAWKGYADIVQLLLAKGARTDLR 169
>3DEO-A nrPDB
Length = 183
Score = 32.7 bits (73), Expect = 0.52, Method: Compositional matrix adjust.
Identities = 19/41 (46%), Positives = 25/41 (60%), Gaps = 1/41 (2%)
Query: 163 GEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGN-TVLHI 202
G L F A +GS++ VRLL E GAD+ +D G T LH+
Sbjct: 76 GRTALLFVAGLGSDKCVRLLAEAGADLDHRDMRGGLTALHM 116
>3UI2-A nrPDB
Length = 244
Score = 32.7 bits (73), Expect = 0.61, Method: Compositional matrix adjust.
Identities = 19/41 (46%), Positives = 25/41 (60%), Gaps = 1/41 (2%)
Query: 163 GEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGN-TVLHI 202
G L F A +GS++ VRLL E GAD+ +D G T LH+
Sbjct: 77 GRTALLFVAGLGSDKCVRLLAEAGADLDHRDMRGGLTALHM 117
>5MKE-A nrPDB
Length = 968
Score = 32.0 bits (71), Expect = 0.91, Method: Compositional matrix adjust.
Identities = 26/108 (24%), Positives = 52/108 (48%), Gaps = 9/108 (8%)
Query: 489 DLMRFCWLMAVVILGFASAFHITFQTEDPNNLGEFSDYPTALFSTFELFLTIIDGPANYS 548
DL F + ++ L +A ++ F T+ + +FS + +F+ F + L I+ A
Sbjct: 596 DLFGFAIMFFIIFLAYAQLAYLVFGTQ----VDDFSTFQECIFTQFRIILGDINF-AEIE 650
Query: 549 VDLPFMYCITYAAFAIIATLLMLNLFIAMMGDTHWRV----AQERDEL 592
+ I + F ++LN+F+A++ DT+ V AQ++ E+
Sbjct: 651 EANRVLGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKSDLAQQKAEM 698
>5UQE-A nrPDB
Length = 520
Score = 32.0 bits (71), Expect = 0.93, Method: Compositional matrix adjust.
Identities = 21/53 (39%), Positives = 29/53 (54%), Gaps = 1/53 (1%)
Query: 49 LLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEA 101
LL AA D+ L+ L+ + D +QR TALHVAA ++E L+EA
Sbjct: 421 LLFAAYTGDVSALRRFALS-AMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEA 472
>1G3N-B nrPDB
Length = 168
Score = 31.6 bits (70), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 18/51 (35%), Positives = 29/51 (56%)
Query: 48 PLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLL 98
PL AAKE LR+++ L+ + + + R G+TA +A LY E +L+
Sbjct: 106 PLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLM 156
>5U0J-A nrPDB
Length = 140
Score = 31.6 bits (70), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 21/53 (39%), Positives = 29/53 (54%), Gaps = 1/53 (1%)
Query: 49 LLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEA 101
LL AA D+ L+ L+ + D +QR TALHVAA ++E L+EA
Sbjct: 28 LLFAAYTGDVSALRRFALS-AMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEA 79
>1DCQ-A nrPDB
Length = 278
Score = 30.8 bits (68), Expect = 2.0, Method: Compositional matrix adjust.
Identities = 22/62 (35%), Positives = 31/62 (50%), Gaps = 9/62 (14%)
Query: 65 LLNQSCDFQQRGAVGETALHVAALYDNLEAATLLM--EAAPELAKEPALCEPFVGQTALH 122
L+ S + ++ G TALH L DN E LL+ +A+ E+A E G+T L
Sbjct: 191 LVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKASIEIANES-------GETPLD 243
Query: 123 IA 124
IA
Sbjct: 244 IA 245
>6BPQ-A nrPDB
Length = 950
Score = 30.8 bits (68), Expect = 2.3, Method: Compositional matrix adjust.
Identities = 37/146 (25%), Positives = 60/146 (41%), Gaps = 25/146 (17%)
Query: 475 LGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFHITFQTEDPN------------NLGE 522
LGP IM+Q+M+ D+ F +L AV ++ F A + + L
Sbjct: 727 LGPKIIMLQRMMI-DVFFFLFLFAVWMVAFGVARQGILRKNEHRWEWIFRSVIYEPYLAM 785
Query: 523 FSDYPTAL-----------FSTFELFLTIIDGPANYSVDLPFMYCITYAAFAIIAT-LLM 570
F YP + FS E ++ AN P I +++T +L+
Sbjct: 786 FGQYPDDIDGTTYNFDHCTFSGNESKPLCVELDANNQPRFPEWITIPLVCIYMLSTNILL 845
Query: 571 LNLFIAMMGDTHWRVAQERDELWRAQ 596
+NL +AM G T V + D++W+ Q
Sbjct: 846 VNLLVAMFGYTVGSVQENNDQVWKFQ 871
>6DU8-A nrPDB
Length = 805
Score = 30.8 bits (68), Expect = 2.4, Method: Compositional matrix adjust.
Identities = 25/108 (23%), Positives = 51/108 (47%), Gaps = 9/108 (8%)
Query: 489 DLMRFCWLMAVVILGFASAFHITFQTEDPNNLGEFSDYPTALFSTFELFLTIIDGPANYS 548
D++ F + +V +A ++ F T+ N FS + +F+ F + L D A +
Sbjct: 476 DILGFAVMFFIVFFAYAQLGYLLFGTQVEN----FSTFIKCIFTQFRIILGDFDYNAIDN 531
Query: 549 VDLPFMYCITYAAFAIIATLLMLNLFIAMMGDTHWRVAQE----RDEL 592
+ + + + ++LN+F+A++ DT+ V +E +DEL
Sbjct: 532 ANR-ILGPAYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELAGQKDEL 578
>3CO4-A nrPDB
Length = 312
Score = 30.4 bits (67), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 18/70 (25%), Positives = 36/70 (51%), Gaps = 4/70 (5%)
Query: 28 DWEQYRDRVNMLQQER--IRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHV 85
+WEQY D +N++ +R D P+ A+ ++ ++ LK N+ C + VG +
Sbjct: 157 EWEQYFDYINLMSYDRGAFTDKPVQHASYDDFVKDLK--YWNEQCRASKSKIVGGLPFYG 214
Query: 86 AALYDNLEAA 95
+ ++L+ A
Sbjct: 215 YSWEESLQGA 224
>6EMK-G nrPDB
Length = 426
Score = 30.4 bits (67), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 41/168 (24%), Positives = 73/168 (43%), Gaps = 19/168 (11%)
Query: 38 MLQQERIRDSPLLQAAKENDLRLLKILLL-NQSCDFQQRGAVGETALHVAALYDNLEAAT 96
ML++ +R L +A E +L ++K LL N G ++LH A+ +
Sbjct: 1 MLKEPSVR---LREAIIEGNLLIVKRLLRRNPDLLTNIDSENGWSSLHYASYHGRYLICV 57
Query: 97 LLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSP 156
L++ + + L + F G T +H+A+M + + LL + F R
Sbjct: 58 YLIQLGHDKHE---LIKTFKGNTCVHLALMKGHEQTLHLLLQQ------------FPRFI 102
Query: 157 HNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILI 204
++ G P+ A + + LLI GAD+ D+ G+T LH+ +
Sbjct: 103 NHRGENGRAPIHIACMNDYYQCLSLLIGVGADLWVMDTNGDTPLHVCL 150
>5U0K-A nrPDB
Length = 141
Score = 30.4 bits (67), Expect = 2.8, Method: Compositional matrix adjust.
Identities = 29/92 (31%), Positives = 41/92 (44%), Gaps = 13/92 (14%)
Query: 49 LLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKE 108
LL AA D+ L+ L+ + D +Q+ TALHVAA ++E L+EA
Sbjct: 29 LLFAAYSGDVSALRRFALS-AMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEACK----- 82
Query: 109 PALCEPFV----GQTALHIAVMNQNLNLVRAL 136
PF G L AV +L +V+ L
Sbjct: 83 ---VNPFAKDRWGNIPLDDAVQFNHLEVVKLL 111
>4BSZ-B nrPDB
Length = 202
Score = 30.0 bits (66), Expect = 3.7, Method: Composition-based stats.
Identities = 21/62 (33%), Positives = 31/62 (50%), Gaps = 7/62 (11%)
Query: 81 TALHVAALYDNLEAATLLMEAAPELAKEPALCEPFV------GQTALHIAVMNQNLNLVR 134
TALH+AA ++E ++E A + FV G TALH A +N L++V+
Sbjct: 54 TALHMAAANGHIETVRYILETVSR-ANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVK 112
Query: 135 AL 136
L
Sbjct: 113 LL 114
>5UIL-A nrPDB
Length = 405
Score = 30.0 bits (66), Expect = 3.9, Method: Compositional matrix adjust.
Identities = 14/38 (36%), Positives = 23/38 (60%)
Query: 162 YGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTV 199
YG P+ AA G+ E+++ L+ GA+I ++ G TV
Sbjct: 310 YGWSPVIVAAYHGNIELIKWLVSKGANINDRNYKGTTV 347
>6D1W-A nrPDB
Length = 740
Score = 30.0 bits (66), Expect = 3.9, Method: Compositional matrix adjust.
Identities = 26/108 (24%), Positives = 52/108 (48%), Gaps = 9/108 (8%)
Query: 489 DLMRFCWLMAVVILGFASAFHITFQTEDPNNLGEFSDYPTALFSTFELFLTIIDGPANYS 548
DL F + ++ L +A ++ F T+ + +FS + +F+ F + L I+ A
Sbjct: 544 DLFGFAIMPFIIFLAYAQLAYLVFGTQ----VDDFSTFQECIFTQFRIILGDINF-AEIE 598
Query: 549 VDLPFMYCITYAAFAIIATLLMLNLFIAMMGDTHWRV----AQERDEL 592
+ I + F ++LN+F+A++ DT+ V AQ++ E+
Sbjct: 599 EANRVLGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKSDLAQQKAEM 646
>6AYG-A nrPDB
Length = 558
Score = 30.0 bits (66), Expect = 4.2, Method: Compositional matrix adjust.
Identities = 33/157 (21%), Positives = 70/157 (44%), Gaps = 18/157 (11%)
Query: 444 LTNMNGEVVPLSFALVLGWCSVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILG 503
LT+ + + L + +L W V+ + F + +Q + +++RFC A++ LG
Sbjct: 372 LTSYDVCSILLGTSTMLVWLGVIRYLGFFAKYNLLILTLQAAL-PNVIRFCCCAAMIYLG 430
Query: 504 FASAFHITFQTEDPNNLGEFSDYPTALFSTFELFLTIIDGPANYSV--------DLPFMY 555
+ I LG + D +L E ++I+G ++ L +++
Sbjct: 431 YCFCGWIV--------LGPYHDKFRSLNMVSECLFSLINGDDMFATFAKMQQKSYLVWLF 482
Query: 556 CITY-AAFAIIATLLMLNLFIAMMGDTHWRVAQERDE 591
Y +F + ++L+LFIA++ DT+ + Q + +
Sbjct: 483 SRIYLYSFISLFIYMILSLFIALITDTYETIKQYQQD 519
>3T9K-A nrPDB
Length = 390
Score = 29.3 bits (64), Expect = 6.8, Method: Compositional matrix adjust.
Identities = 25/98 (25%), Positives = 42/98 (42%), Gaps = 6/98 (6%)
Query: 36 VNMLQQERIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAA 95
VN + + +PL+QA N L + LL N + Q + G LH A + + A
Sbjct: 226 VNWVNGGQDNATPLIQATAANSLLACEFLLQN-GANVNQADSAGRGPLHHATILGHTGLA 284
Query: 96 TLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLV 133
L ++ +L + G+ L IA+ N ++V
Sbjct: 285 CLFLKRGADLGARDS-----EGRDPLTIAMETANADIV 317
>5T4D-A nrPDB
Length = 510
Score = 28.9 bits (63), Expect = 7.3, Method: Compositional matrix adjust.
Identities = 29/115 (25%), Positives = 54/115 (46%), Gaps = 23/115 (20%)
Query: 489 DLMRFCWLMAVVILGFASAFHITFQTEDPNNLGEFSDYPTALFSTFELFLTIIDGPANYS 548
DL F + ++ L +A ++ F T+ + +FS + +F+ F II G N++
Sbjct: 404 DLFGFAIMFFIIFLAYAQLAYLVFGTQ----VDDFSTFQECIFTQFR----IILGDINFA 455
Query: 549 -------VDLPFMYCITYAAFAIIATLLMLNLFIAMMGDTHWRV----AQERDEL 592
V P I + F ++LN+F+A++ DT+ V AQ++ E+
Sbjct: 456 EIEEANRVLGP----IYFTTFVFFMFFILLNMFLAIINDTYSEVKSDLAQQKAEM 506
>5D68-A nrPDB
Length = 486
Score = 28.9 bits (63), Expect = 7.4, Method: Compositional matrix adjust.
Identities = 39/164 (23%), Positives = 59/164 (35%), Gaps = 52/164 (31%)
Query: 40 QQERIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLM 99
+++ + D PL ++A E D LL LL++ Q + +H A Y +EA +L+
Sbjct: 33 ERQWVDDFPLHRSACEGDSELLS-RLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILL 91
Query: 100 EAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNL 159
E C P NL+ L+
Sbjct: 92 EKGK--------CNP----------------NLLNGQLSS-------------------- 107
Query: 160 IYYGEHPLSFAACVGSEEIVRLLIEH-GADIRAQDSLGNTVLHI 202
PL FAA G EIV++L+ H D D G + L+I
Sbjct: 108 ------PLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 145
Searching..................................................done
Results from round 2
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
6DMR-A nrPDB 1056 0.0
6BOA-A nrPDB 1002 0.0
6E2G-A nrPDB 994 0.0
6BBJ-A nrPDB 608 e-174
6C8G-A nrPDB 600 e-172
6DVZ-A nrPDB 595 e-170
5IRX-A nrPDB 594 e-170
6MHW-A nrPDB 580 e-166
6OO7-A nrPDB 548 e-156
5AN8-A nrPDB 541 e-154
5HI9-A nrPDB 531 e-151
6BO5-A nrPDB 526 e-149
2RFA-A nrPDB 288 7e-78
2ETB-A nrPDB 223 3e-58
2F37-A nrPDB 221 7e-58
3W9G-A nrPDB 197 1e-50
4DX2-A nrPDB 196 2e-50
5H76-A nrPDB 195 5e-50
6MWQ-A nrPDB 195 6e-50
5AQ9-A nrPDB 193 2e-49
4N5Q-A nrPDB 193 4e-49
5AQA-A nrPDB 192 5e-49
5MIO-C nrPDB 189 4e-48
2NYJ-A nrPDB 187 1e-47
5AQB-A nrPDB 187 1e-47
5AQ7-A nrPDB 186 2e-47
4OAU-C nrPDB 184 1e-46
6FES-A nrPDB 179 3e-45
6G1K-A nrPDB 175 6e-44
3B7B-A nrPDB 173 2e-43
6AUN-A nrPDB 167 2e-41
5Z96-A nrPDB 162 5e-40
4Z68-A nrPDB 161 9e-40
5GP7-A nrPDB 158 9e-39
5CBO-A nrPDB 132 7e-31
5OEO-C nrPDB 95 9e-20
4OT9-A nrPDB 94 3e-19
Sequences not found previously or not previously below threshold:
6BY9-A nrPDB 172 5e-43
4O1O-A nrPDB 150 2e-36
5JHQ-A nrPDB 141 1e-33
5HKP-A nrPDB 139 4e-33
2DWZ-A nrPDB 116 3e-26
4NIK-A nrPDB 116 4e-26
5ET1-A nrPDB 105 7e-23
3EU9-A nrPDB 101 1e-21
3ZKJ-A nrPDB 96 4e-20
6CUD-A nrPDB 94 2e-19
1BD8-A nrPDB 91 2e-18
1WG0-A nrPDB 90 4e-18
6CV9-A nrPDB 86 5e-17
1BLX-B nrPDB 83 4e-16
3LJN-A nrPDB 77 2e-14
1G3N-B nrPDB 70 3e-12
5DND-A nrPDB 69 7e-12
6EMK-G nrPDB 68 1e-11
2KXP-C nrPDB 68 2e-11
3T9K-A nrPDB 67 3e-11
5D68-A nrPDB 66 6e-11
3UI2-A nrPDB 66 6e-11
3EHQ-A nrPDB 66 8e-11
3DEO-A nrPDB 65 9e-11
1D9S-A nrPDB 60 5e-09
6BWF-A nrPDB 57 2e-08
6DJS-A nrPDB 57 3e-08
4BSZ-B nrPDB 56 4e-08
5U0K-A nrPDB 54 3e-07
6BPQ-A nrPDB 52 6e-07
1DCQ-A nrPDB 51 2e-06
5UQE-A nrPDB 50 3e-06
5U0J-A nrPDB 50 3e-06
2A5E-A nrPDB 50 3e-06
5Z1W-A nrPDB 45 9e-05
3LVQ-E nrPDB 45 1e-04
2B0O-E nrPDB 45 1e-04
6DU8-A nrPDB 45 1e-04
5UIL-A nrPDB 42 8e-04
5MKE-A nrPDB 41 0.002
5EK0-A nrPDB 41 0.002
5T4D-A nrPDB 41 0.002
5WPT-A nrPDB 41 0.002
6E7Z-A nrPDB 39 0.009
4DXW-A nrPDB 39 0.010
6D1W-A nrPDB 39 0.010
3RVY-A nrPDB 39 0.010
6AYG-A nrPDB 37 0.020
4XD0-A nrPDB 37 0.023
6BWI-A nrPDB 35 0.089
4GX0-A nrPDB 35 0.14
6N4I-A nrPDB 35 0.17
5E1J-A nrPDB 33 0.51
2GBW-A nrPDB 32 1.1
3G2F-A nrPDB 31 2.4
2FT0-A nrPDB 30 3.3
3CO4-A nrPDB 30 3.3
2N4X-A nrPDB 29 7.2
>6DMR-A nrPDB
Length = 730
Score = 1056 bits (2731), Expect = 0.0, Method: Composition-based stats.
Identities = 730/730 (100%), Positives = 730/730 (100%)
Query: 1 MGACPPKAKGPWAQLQKLLISWPVGEQDWEQYRDRVNMLQQERIRDSPLLQAAKENDLRL 60
MGACPPKAKGPWAQLQKLLISWPVGEQDWEQYRDRVNMLQQERIRDSPLLQAAKENDLRL
Sbjct: 1 MGACPPKAKGPWAQLQKLLISWPVGEQDWEQYRDRVNMLQQERIRDSPLLQAAKENDLRL 60
Query: 61 LKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTA 120
LKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTA
Sbjct: 61 LKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTA 120
Query: 121 LHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVR 180
LHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVR
Sbjct: 121 LHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVR 180
Query: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQG 240
LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQG
Sbjct: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQG 240
Query: 241 LTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSWGEELSFLELVVSSK 300
LTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSWGEELSFLELVVSSK
Sbjct: 241 LTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSWGEELSFLELVVSSK 300
Query: 301 KREARQILEQTPVKELVSFKWKKYGRPYFCVLASLYILYMICFTTCCIYRPLKLRDDNRT 360
KREARQILEQTPVKELVSFKWKKYGRPYFCVLASLYILYMICFTTCCIYRPLKLRDDNRT
Sbjct: 301 KREARQILEQTPVKELVSFKWKKYGRPYFCVLASLYILYMICFTTCCIYRPLKLRDDNRT 360
Query: 361 DPRDITILQQKLLQEAYVTHQDNIRLVGELVTVTGAVIILLLEIPDIFRVGASRYFGQTI 420
DPRDITILQQKLLQEAYVTHQDNIRLVGELVTVTGAVIILLLEIPDIFRVGASRYFGQTI
Sbjct: 361 DPRDITILQQKLLQEAYVTHQDNIRLVGELVTVTGAVIILLLEIPDIFRVGASRYFGQTI 420
Query: 421 LGGPFHVIIITYASLVLLTMVMRLTNMNGEVVPLSFALVLGWCSVMYFARGFQMLGPFTI 480
LGGPFHVIIITYASLVLLTMVMRLTNMNGEVVPLSFALVLGWCSVMYFARGFQMLGPFTI
Sbjct: 421 LGGPFHVIIITYASLVLLTMVMRLTNMNGEVVPLSFALVLGWCSVMYFARGFQMLGPFTI 480
Query: 481 MIQKMIFGDLMRFCWLMAVVILGFASAFHITFQTEDPNNLGEFSDYPTALFSTFELFLTI 540
MIQKMIFGDLMRFCWLMAVVILGFASAFHITFQTEDPNNLGEFSDYPTALFSTFELFLTI
Sbjct: 481 MIQKMIFGDLMRFCWLMAVVILGFASAFHITFQTEDPNNLGEFSDYPTALFSTFELFLTI 540
Query: 541 IDGPANYSVDLPFMYCITYAAFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVAT 600
IDGPANYSVDLPFMYCITYAAFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVAT
Sbjct: 541 IDGPANYSVDLPFMYCITYAAFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVAT 600
Query: 601 TVMLERKMPRFLWPRSGICGYEYGLGDRWFLRVENHHDQNPLRVLRYVEAFKCSDKEDGQ 660
TVMLERKMPRFLWPRSGICGYEYGLGDRWFLRVENHHDQNPLRVLRYVEAFKCSDKEDGQ
Sbjct: 601 TVMLERKMPRFLWPRSGICGYEYGLGDRWFLRVENHHDQNPLRVLRYVEAFKCSDKEDGQ 660
Query: 661 EQLSEKRPSTVESGMLSRASVAFQTPSLSRTTSQSSNSHRGWEILRRNTLGHLNLGLDLG 720
EQLSEKRPSTVESGMLSRASVAFQTPSLSRTTSQSSNSHRGWEILRRNTLGHLNLGLDLG
Sbjct: 661 EQLSEKRPSTVESGMLSRASVAFQTPSLSRTTSQSSNSHRGWEILRRNTLGHLNLGLDLG 720
Query: 721 EGDGEEVYHF 730
EGDGEEVYHF
Sbjct: 721 EGDGEEVYHF 730
>6BOA-A nrPDB
Length = 742
Score = 1002 bits (2590), Expect = 0.0, Method: Composition-based stats.
Identities = 538/727 (74%), Positives = 602/727 (82%), Gaps = 12/727 (1%)
Query: 1 MGACPPKAKGPWAQLQKLLISWPVGEQDWEQYRDRVNMLQQERIRDSPLLQAAKENDLRL 60
MG PK KG L W + W Q RD N+LQQ+RI +SPLL AAK+ND++
Sbjct: 1 MGLSLPKEKGLILCLWSKFCRWFQRRESWAQSRDEQNLLQQKRIWESPLLLAAKDNDVQA 60
Query: 61 LKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTA 120
L LL + C QRGA+GETALH+AALYDNLEAA +LMEAAPEL EP E + GQTA
Sbjct: 61 LNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTA 120
Query: 121 LHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVR 180
LHIAV+NQN+NLVRALLAR ASVSARATG AFRRSP NLIY+GEHPLSFAACV SEEIVR
Sbjct: 121 LHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVR 180
Query: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQG 240
LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD H DHLQ L+LVPNHQG
Sbjct: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQG 240
Query: 241 LTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSWGEELSFLELVVSSK 300
LTPFKLAGVEGNTVMFQHLMQKRKH QWT GPLTSTLYDLTEIDS G+E S LEL++++K
Sbjct: 241 LTPFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEIDSSGDEQSLLELIITTK 300
Query: 301 KREARQILEQTPVKELVSFKWKKYGRPYFCVLASLYILYMICFTTCCIYRPLKLRDDNRT 360
KREARQIL+QTPVKELVS KWK+YGRPYFC+L ++Y+LY+ICFT CCIYRPLK R +NRT
Sbjct: 301 KREARQILDQTPVKELVSLKWKRYGRPYFCMLGAIYLLYIICFTMCCIYRPLKPRTNNRT 360
Query: 361 DPRDITILQQKLLQEAYVTHQDNIRLVGELVTVTGAVIILLLEIPDIFRVGASRYFGQTI 420
PRD T+LQQKLLQEAY+T +D+IRLVGELVTV GA+IILL+E+PDIFR+G +R+FGQTI
Sbjct: 361 SPRDNTLLQQKLLQEAYMTPKDDIRLVGELVTVIGAIIILLVEVPDIFRMGVTRFFGQTI 420
Query: 421 LGGPFHVIIITYASLVLLTMVMRLTNMNGEVVPLSFALVLGWCSVMYFARGFQMLGPFTI 480
LGGPFHV+IITYA +VL+TMVMRL + +GEVVP+SFALVLGWC+VMYFA GFQMLGPFTI
Sbjct: 421 LGGPFHVLIITYAFMVLVTMVMRLISASGEVVPMSFALVLGWCNVMYFAEGFQMLGPFTI 480
Query: 481 MIQKMIFGDLMRFCWLMAVVILGFASAFHITFQTEDPNNLGEFSDYPTALFSTFELFLTI 540
MIQKMIFGDLMRFCWLMAVVILGFASAF+I FQTEDP LG F DYP ALFSTFELFLTI
Sbjct: 481 MIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPEELGHFYDYPMALFSTFELFLTI 540
Query: 541 IDGPANYSVDLPFMYCITYAAFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVAT 600
IDGPANY+VDLPFMY ITYAAFAIIATLLMLNL IAMMGDTHWRVA ERDELWRAQ+VAT
Sbjct: 541 IDGPANYNVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVAT 600
Query: 601 TVMLERKMPRFLWPRSGICGYEYGLGDRWFLRVENHHDQNPLRVLRYVEAFKCSDKEDGQ 660
TVMLERK+PR LWPRSGICG EYGLGDRWFLRVE+ D N R+ RY +AF ED
Sbjct: 601 TVMLERKLPRCLWPRSGICGREYGLGDRWFLRVEDRQDLNRQRIQRYAQAFHTRGSEDLD 660
Query: 661 EQLSEKRPSTVESGMLSRASVAFQTPSLSRTTSQSSNSHRGWEILRRNTL-----GHLNL 715
+ EK +E G ++ PS+SR+TS+SS + WE LR+ TL G +N
Sbjct: 661 KDSVEK----LELGCPFSPHLSLPMPSVSRSTSRSSAN---WERLRQGTLRRDLRGIINR 713
Query: 716 GLDLGEG 722
GL+ GE
Sbjct: 714 GLEDGES 720
>6E2G-A nrPDB
Length = 727
Score = 994 bits (2571), Expect = 0.0, Method: Composition-based stats.
Identities = 541/734 (73%), Positives = 610/734 (83%), Gaps = 24/734 (3%)
Query: 1 MGACPPKAKGPWAQLQKLLISWPVGEQDWEQYRDRVNMLQQERIRDSPLLQAAKENDLRL 60
MG PK KG L W + W Q RD N+LQQ+RI +SPLL AAKEN+++
Sbjct: 1 MGWSLPKEKGLILCLWNKFCRWFHRRESWAQSRDEQNLLQQKRIWESPLLLAAKENNVQA 60
Query: 61 LKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTA 120
L LL + C+ Q+GA+GETALH+AALYDNLEAA +LMEAAPEL EP E + GQTA
Sbjct: 61 LIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTA 120
Query: 121 LHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVR 180
LHIAV+NQN+NLVRALLARGASVSARATG+ F PHNLIYYGEHPLSFAACVGSEEIVR
Sbjct: 121 LHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVR 180
Query: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQG 240
LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD DHL+SLELVPN+QG
Sbjct: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDG-GDHLKSLELVPNNQG 239
Query: 241 LTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSWGEELSFLELVVSSK 300
LTPFKLAGVEGN VMFQHLMQKRKH+QWT GPLTSTLYDLTEIDS G++ S LEL+V++K
Sbjct: 240 LTPFKLAGVEGNIVMFQHLMQKRKHIQWTYGPLTSTLYDLTEIDSSGDDQSLLELIVTTK 299
Query: 301 KREARQILEQTPVKELVSFKWKKYGRPYFCVLASLYILYMICFTTCCIYRPLKLRDDNRT 360
KREARQIL+QTPVKELVS KWK+YGRPYFCVL ++Y+LY+ICFT CC+YRPLK R NRT
Sbjct: 300 KREARQILDQTPVKELVSLKWKRYGRPYFCVLGAIYVLYIICFTMCCVYRPLKPRITNRT 359
Query: 361 DPRDITILQQKLLQEAYVTHQDNIRLVGELVTVTGAVIILLLEIPDIFRVGASRYFGQTI 420
+PRD T+LQQKLLQEAYVT +D++RLVGELV++ GAVIILL+EIPDIFR+G +R+FGQTI
Sbjct: 360 NPRDNTLLQQKLLQEAYVTPKDDLRLVGELVSIVGAVIILLVEIPDIFRLGVTRFFGQTI 419
Query: 421 LGGPFHVIIITYASLVLLTMVMRLTNMNGEVVPLSFALVLGWCSVMYFARGFQMLGPFTI 480
LGGPFHVII+TYA +VL+TMVMRLTN +GEVVP+SFALVLGWC+VMYFARGFQMLGPFTI
Sbjct: 420 LGGPFHVIIVTYAFMVLVTMVMRLTNSDGEVVPMSFALVLGWCNVMYFARGFQMLGPFTI 479
Query: 481 MIQKMIFGDLMRFCWLMAVVILGFASAFHITFQTEDPNNLGEFSDYPTALFSTFELFLTI 540
MIQKMIFGDLMRFCWLMAVVILGFASAF+I FQTEDP+ LG F DYP ALFSTFELFLTI
Sbjct: 480 MIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPDELGHFYDYPMALFSTFELFLTI 539
Query: 541 IDGPANYSVDLPFMYCITYAAFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVAT 600
IDGPANY VDLPFMY ITYAAFAIIATLLMLNL IAMMGDTHWRVA ERDELWRAQVVAT
Sbjct: 540 IDGPANYDVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQVVAT 599
Query: 601 TVMLERKMPRFLWPRSGICGYEYGLGDRWFLRVENHHDQNPLRVLRYVEAFKCSD----- 655
TVMLERK+PR LWPRSGICG EYGLGDRWFLRVE+ D N R+ RY +AF+ D
Sbjct: 600 TVMLERKLPRCLWPRSGICGREYGLGDRWFLRVEDRQDLNRQRIRRYAQAFQQQDDLYSE 659
Query: 656 --KEDGQEQLSEKRPSTVESGMLSRASVAFQTPSLSRTTSQSSNSHRGWEILRRNTL--- 710
++D E+L RP A ++F TPS+SR+TS+SS + W+ LR+ L
Sbjct: 660 DLEKDSGEKLEMARPFG--------AYLSFPTPSVSRSTSRSSTN---WDRLRQGALRKD 708
Query: 711 --GHLNLGLDLGEG 722
G +N GL+ GEG
Sbjct: 709 LQGIINRGLEDGEG 722
>6BBJ-A nrPDB
Length = 868
Score = 608 bits (1568), Expect = e-174, Method: Composition-based stats.
Identities = 192/624 (30%), Positives = 306/624 (49%), Gaps = 81/624 (12%)
Query: 77 AVGETALHVAALY---DNLEAATLLME------AAPELAKEPALCEPFVGQTALHIAVMN 127
+ G+T L A + + +L++ E P + GQTALHIA+
Sbjct: 185 STGKTCLTKALMNLNGGKNDTIPMLIDIAEKTGNLREFINSPFRDVYYRGQTALHIAIER 244
Query: 128 QNLNLVRALLARGASVSARATGAAFR-RSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHG 186
+ + V L+ +GA V A+A G F+ + Y+GE PLS AAC +IV L E+
Sbjct: 245 RCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPDIVHYLTENA 304
Query: 187 ---ADIRAQDSLGNTVLHILI-----LQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNH 238
ADIR QDS GNTVLH L+ + N F ++Y+LL+ SLE + N+
Sbjct: 305 HKKADIRRQDSRGNTVLHALVAIADNTRENTKFVTKVYDLLVIKCVKLYPDSSLEAIFNN 364
Query: 239 QGLTPFKLAGVEGNTVMFQHLMQ-----------KRKHVQWTCGPLTSTLYDLTEIDSWG 287
++P +A G +FQH+++ RK W GP+ S+LYDL+ +D+ G
Sbjct: 365 DSMSPLMMAAKLGKIGIFQHIIRLEIKDEEARHLSRKFRDWAYGPVYSSLYDLSMLDTCG 424
Query: 288 EELSFLELVVSSKKREAR-QILEQTPVKELVSFKWKKYGRPYFCVLASLYILYMICFTTC 346
EE+S LE++V + K E R ++L P+ EL+ KW+K+G F + Y++ MI FT
Sbjct: 425 EEVSVLEILVYNSKVENRHEMLAVEPINELLRDKWQKFGAVSFYISVVSYLIAMIIFTLI 484
Query: 347 CIYRPLKLRDDNRTDPRDITILQQKLLQEAYVTHQDNIRLVGELVTVTGAVIILLLEIPD 406
YRP+ + T P Y T D +RL GE+VT+ V+ + I D
Sbjct: 485 AYYRPM-----DGTPPY------------PYRTTMDYMRLAGEIVTLLTGVVFFITNIKD 527
Query: 407 IFRV---GASRYFGQTILGGPFHVIIITYASLVLLTMVMRLTNMNGEVVPLSFALVLGWC 463
+F G + F + G F ++ Y+ LV++T V+ L + + + FALVLGW
Sbjct: 528 LFMKKCPGVNSLF----IDGSFQLLYFIYSVLVIITAVLYLVGIESYLAVMVFALVLGWM 583
Query: 464 SVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAF----------HITFQ 513
+ +YF RG ++ G ++IM+QK++F DL RF + + ++G+ASA +
Sbjct: 584 NALYFTRGLKLTGTYSIMLQKILFKDLFRFLLVYLLFMIGYASALVSLLNPCTSQESCIE 643
Query: 514 TEDPNNLGEFSD------YPTALFSTFELFLTIIDGPANYSVDLPFMYCITYAAFAIIAT 567
T + E+ + L F+L + + D S P ++ I + I+
Sbjct: 644 TSSNCTVPEYPSCRDSSTFSKFLLDLFKLTIGMGDLEMINSAKYPAVFIILLVTYIILTF 703
Query: 568 LLMLNLFIAMMGDTHWRVAQERDELWRAQVVATTVMLERKMPRFLWP--RSG----ICGY 621
+L+LN+ IA+MG+T +V++E ++W+ Q T + +ER P + RSG +
Sbjct: 704 VLLLNMLIALMGETVGQVSKESKQIWKLQWATTILDIERSFPVCMRKAFRSGEMVTVGKN 763
Query: 622 EYGLGD-RWFLRVE----NHHDQN 640
G D RW RV+ +H +QN
Sbjct: 764 LDGTPDRRWCFRVDEVNWSHWNQN 787
>6C8G-A nrPDB
Length = 675
Score = 600 bits (1547), Expect = e-172, Method: Composition-based stats.
Identities = 192/624 (30%), Positives = 306/624 (49%), Gaps = 81/624 (12%)
Query: 77 AVGETALHVAALY---DNLEAATLLME------AAPELAKEPALCEPFVGQTALHIAVMN 127
+ G+T L A + + +L++ E P + GQTALHIA+
Sbjct: 54 STGKTCLTKALMNLNGGKNDTIPMLIDIAEKTGNLREFINSPFRDVYYRGQTALHIAIER 113
Query: 128 QNLNLVRALLARGASVSARATGAAFR-RSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHG 186
+ + V L+ +GA V A+A G F+ + Y+GE PLS AAC +IV L E+
Sbjct: 114 RCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPDIVHYLTENA 173
Query: 187 ---ADIRAQDSLGNTVLHILI-----LQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNH 238
ADIR QDS GNTVLH L+ + N F ++Y+LL+ SLE + N+
Sbjct: 174 HKKADIRRQDSRGNTVLHALVAIADNTRENTKFVTKVYDLLVIKCVKLYPDSSLEAIFNN 233
Query: 239 QGLTPFKLAGVEGNTVMFQHLMQ-----------KRKHVQWTCGPLTSTLYDLTEIDSWG 287
++P +A G +FQH+++ RK W GP+ S+LYDL+ +D+ G
Sbjct: 234 DSMSPLMMAAKLGKIGIFQHIIRLEIKDEEARHLSRKFRDWAYGPVYSSLYDLSMLDTCG 293
Query: 288 EELSFLELVVSSKKREAR-QILEQTPVKELVSFKWKKYGRPYFCVLASLYILYMICFTTC 346
EE+S LE++V + K E R ++L P+ EL+ KW+K+G F + Y++ MI FT
Sbjct: 294 EEVSVLEILVYNSKVENRHEMLAVEPINELLRDKWQKFGAVSFYISVVSYLIAMIIFTLI 353
Query: 347 CIYRPLKLRDDNRTDPRDITILQQKLLQEAYVTHQDNIRLVGELVTVTGAVIILLLEIPD 406
YRP+ + T P Y T D +RL GE+VT+ V+ + I D
Sbjct: 354 AYYRPM-----DGTPPY------------PYRTTMDYMRLAGEIVTLLTGVVFFITNIKD 396
Query: 407 IFRV---GASRYFGQTILGGPFHVIIITYASLVLLTMVMRLTNMNGEVVPLSFALVLGWC 463
+F G + F + G F ++ Y+ LV++T V+ L + + + FALVLGW
Sbjct: 397 LFMKKCPGVNSLF----IDGSFQLLYFIYSVLVIITAVLYLVGIESYLAVMVFALVLGWM 452
Query: 464 SVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAF----------HITFQ 513
+ +YF RG ++ G ++IM+QK++F DL RF + + ++G+ASA +
Sbjct: 453 NALYFTRGLKLTGTYSIMLQKILFKDLFRFLLVYLLFMIGYASALVSLLNPCTSQESCIE 512
Query: 514 TEDPNNLGEFSD------YPTALFSTFELFLTIIDGPANYSVDLPFMYCITYAAFAIIAT 567
T + E+ + L F+L + + D S P ++ I + I+
Sbjct: 513 TSSQCTVPEYPSCRDSSTFSKFLLDLFKLTIGMGDLEMINSAKYPAVFIILLVTYIILTF 572
Query: 568 LLMLNLFIAMMGDTHWRVAQERDELWRAQVVATTVMLERKMPRFLWP--RSG----ICGY 621
+L+LN+ IA+MG+T +V++E ++W+ Q T + +ER P + RSG +
Sbjct: 573 VLLLNMLIALMGETVGQVSKESKQIWKLQWATTILDIERSFPVCMRKAFRSGEMVTVGKN 632
Query: 622 EYGLGD-RWFLRVE----NHHDQN 640
G D RW RV+ +H +QN
Sbjct: 633 LDGTPDRRWCFRVDEVNWSHWNQN 656
>6DVZ-A nrPDB
Length = 791
Score = 595 bits (1535), Expect = e-170, Method: Composition-based stats.
Identities = 179/676 (26%), Positives = 309/676 (45%), Gaps = 82/676 (12%)
Query: 49 LLQAAKENDLRLLKILLL--------NQSCDFQQ-------RGAVGETALHVAALY---D 90
+ A E + L+ LL + D G+T L A L +
Sbjct: 123 IFAAVSEGCVEELRELLQDLQDLCRRRRGLDVPDFLMHKLTASDTGKTCLMKALLNINPN 182
Query: 91 NLEAATLLMEAAPELAKEPA------LCEPFVGQTALHIAVMNQNLNLVRALLARGASVS 144
E +L+ A E E + GQTAL+IA+ + ++ L+A GA V+
Sbjct: 183 TKEIVRILLAFAEENDILDRFINAEYTEEAYEGQTALNIAIERRQGDITAVLIAAGADVN 242
Query: 145 ARATGAAFR-RSPHNLIYYGEHPLSFAACVGSEEIVRLLIEH-GADIRAQDSLGNTVLHI 202
A A G F + H Y+GE PL+ AAC EIV+LL+E+ DI +QDS GN +LH
Sbjct: 243 AHAKGVFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMENEQTDITSQDSRGNNILHA 302
Query: 203 LI-----LQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQ 257
L+ + F +MY+++L + + LE + N+ GLTP +LA G + +
Sbjct: 303 LVTVAEDFKTQNDFVKRMYDMILLRSGNWE----LETMRNNDGLTPLQLAAKMGKAEILK 358
Query: 258 HLMQK-----------RKHVQWTCGPLTSTLYDLTEIDSWGEELSFLELVVSSKKREAR- 305
+++ + RK W GP++S+LYDLT +D+ + S LE++V + + R
Sbjct: 359 YILSREIKEKPLRSLSRKFTDWAYGPVSSSLYDLTNVDTTTD-NSVLEIIVYNTNIDNRH 417
Query: 306 QILEQTPVKELVSFKWKKYGRPYFCVLASLYILYMICFTTCCIYRPLKLRDDNRTDPRDI 365
++L P+ L+ KWKK+ + F + Y Y I T YRP +
Sbjct: 418 EMLTLEPLHTLLHTKWKKFAKYMFFLSFCFYFFYNITLTLVSYYRPRE------------ 465
Query: 366 TILQQKLLQEAYVTHQDN-IRLVGELVTVTGAVIILLLEIPDIFRVGASRYFGQTILGGP 424
+ L +TH+ + ++L+G + + A I + E IF + S Q+IL
Sbjct: 466 ---DEDLPHPLALTHKMSWLQLLGRMFVLIWATCISVKEGIAIFLLRPSDL--QSILSDA 520
Query: 425 -FHVIIITYASLVLLTMVMRLTNMNGEVVPLSFALVLGWCSVMYFARGFQMLGPFTIMIQ 483
FH + A LV+L++ + L + L A+ LGW +++ + RGFQ +G +++MIQ
Sbjct: 521 WFHFVFFVQAVLVILSVFLYLFAYKEYLACLVLAMALGWANMLAYTRGFQSMGMYSVMIQ 580
Query: 484 KMIFGDLMRFCWLMAVVILGFASAFHITFQ--TEDPNNLGEFSDYPTALFSTFELFLTII 541
K+I D+++F ++ + +LGF A + ++D + + + A+ F+L + +
Sbjct: 581 KVILHDVLKFLFVYILFLLGFGVALASLIEKCSKDKKDCSSYGSFSDAVLELFKLTIGLG 640
Query: 542 DGPANYSVDLPFMYCITYAAFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVATT 601
D + P ++ + I+ +L+LN+ IA+MG+T V++E + +WR Q T
Sbjct: 641 DLNIQQNSTYPILFLFLLITYVILTFVLLLNMLIALMGETVENVSKESERIWRLQRARTI 700
Query: 602 VMLERKMPRFLWP--RSGICGYEYGLGDRWFLRV-ENHH----------DQNPLRVLRYV 648
+ E+ +P +L R G R LR+ E +++P + R
Sbjct: 701 LEFEKMLPEWLRSRFRMGELCKVADEDFRLCLRINEVKWTEWKTHVSFLNEDPGPIRRTA 760
Query: 649 EAFKCSDKEDGQEQLS 664
+ K D + +
Sbjct: 761 DLNKIQDSSRSNSKTT 776
Score = 45.9 bits (107), Expect = 7e-05, Method: Composition-based stats.
Identities = 33/170 (19%), Positives = 61/170 (35%), Gaps = 8/170 (4%)
Query: 17 KLLISWPVGEQDWEQYRDRVNMLQQERIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRG 76
I+ E+ +E + +N+ + R D + A D+ + +
Sbjct: 201 DRFINAEYTEEAYE-GQTALNIAIERRQGDITAVLIAAGADVNAHAKGVFFNPKYQHEGF 259
Query: 77 AVGETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALH-IAVMNQNLNLVRA 135
GET L +AA + E LLME + + G LH + + ++
Sbjct: 260 YFGETPLALAACTNQPEIVQLLMEN----EQTDITSQDSRGNNILHALVTVAEDFKTQND 315
Query: 136 LLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEH 185
+ R + +G + N G PL AA +G EI++ ++
Sbjct: 316 FVKRMYDMILLRSGNWELETMRNND--GLTPLQLAAKMGKAEILKYILSR 363
>5IRX-A nrPDB
Length = 636
Score = 594 bits (1530), Expect = e-170, Method: Composition-based stats.
Identities = 176/644 (27%), Positives = 294/644 (45%), Gaps = 74/644 (11%)
Query: 46 DSPLLQAAKENDLRLLKILLLN-QSCDFQQRGA------VGETALHVAALY---DNLEAA 95
+ A +++ + L+ LL Q + + G+T L A L +
Sbjct: 9 RRSIFDAVAQSNCQELESLLPFLQRSKKRLTDSEFKDPETGKTCLLKAMLNLHNGQNDTI 68
Query: 96 TLLMEAAPELAKEPALCEP------FVGQTALHIAVMNQNLNLVRALLARGASVSARATG 149
LL++ A + + GQTALHIA+ +N+ LV L+ GA V A A G
Sbjct: 69 ALLLDVARKTDSLKQFVNASYTDSYYKGQTALHIAIERRNMTLVTLLVENGADVQAAANG 128
Query: 150 AAFRRSPHNL-IYYGEHPLSFAACVGSEEIVRLLIEH---GADIRAQDSLGNTVLHILIL 205
F+++ Y+GE PLS AAC IV+ L+++ ADI A+DS+GNTVLH L+
Sbjct: 129 DFFKKTKGRPGFYFGELPLSLAACTNQLAIVKFLLQNSWQPADISARDSVGNTVLHALVE 188
Query: 206 QPNKT-----FACQMYNLLLSYDEHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLM 260
+ T F MYN +L LE + N +GLTP LA G + +++
Sbjct: 189 VADNTVDNTKFVTSMYNEILILGAKLHPTLKLEEITNRKGLTPLALAASSGKIGVLAYIL 248
Query: 261 QK-----------RKHVQWTCGPLTSTLYDLTEIDSWGEELSFLELVVSS--KKREARQI 307
Q+ RK +W GP+ S+LYDL+ ID+ E+ S LE++ S + +
Sbjct: 249 QREIHEPECRHLSRKFTEWAYGPVHSSLYDLSCIDTC-EKNSVLEVIAYSSSETPNRHDM 307
Query: 308 LEQTPVKELVSFKWKKYGRPYFCVLASLYILYMICFTTCCIYRPLKLRDDNRTDPRDITI 367
L P+ L+ KW ++ + F +Y LYMI FT YRP++ P
Sbjct: 308 LLVEPLNRLLQDKWDRFVKRIFYFNFFVYCLYMIIFTAAAYYRPVE-----GLPPY---- 358
Query: 368 LQQKLLQEAYVTHQDNIRLVGELVTVTGAVIILLLEIPDIFRVGASRYFGQTILGGPFHV 427
+ T D R+ GE+++V+G V I + S + +
Sbjct: 359 -------KLKNTVGDYFRVTGEILSVSGGVYFFFRGIQYFLQRRPSL--KSLFVDSYSEI 409
Query: 428 IIITYASLVLLTMVMRLTNMNGEVVPLSFALVLGWCSVMYFARGFQMLGPFTIMIQKMIF 487
+ + +L+++V+ + V + F+L +GW +++Y+ RGFQ +G + +MI+KMI
Sbjct: 410 LFFVQSLFMLVSVVLYFSQRKEYVASMVFSLAMGWTNMLYYTRGFQQMGIYAVMIEKMIL 469
Query: 488 GDLMRFCWLMAVVILGFASAFHITFQTEDPNNLGEFSDYPTALFSTFELFLTIIDGPANY 547
DL RF ++ V + GF++A + G+++ + F+ + + D
Sbjct: 470 RDLCRFMFVYLVFLFGFSTAVVTLIED------GKYNSLYSTCLELFKFTIGMGDLEFTE 523
Query: 548 SVDLPFMYCITYAAFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVATTVMLERK 607
+ D ++ I A+ I+ +L+LN+ IA+MG+T ++AQE +W+ Q T + E+
Sbjct: 524 NYDFKAVFIILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAITILDTEKS 583
Query: 608 MPRFLWP--RSGI---CGYEYGLGD--RWFLRVEN----HHDQN 640
+ + RSG G+ D RW RV+ + N
Sbjct: 584 FLKCMRKAFRSGKLLQVGFTPDGKDDYRWCFRVDEVNWTTWNTN 627
>6MHW-A nrPDB
Length = 826
Score = 580 bits (1495), Expect = e-166, Method: Composition-based stats.
Identities = 171/617 (27%), Positives = 292/617 (47%), Gaps = 60/617 (9%)
Query: 53 AKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALY---DNLEAATLLMEAAPELA--- 106
+ + L+ G+T L A L + E +L+ A E
Sbjct: 147 CRRRHDEDVPDFLM----HKLTASDTGKTCLMKALLNINPNTKEIVRILLAFAEENDILG 202
Query: 107 ---KEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFR-RSPHNLIYY 162
E + GQTAL+IA+ + ++ L+A GA V+A A GA F + H Y+
Sbjct: 203 RFINAEYTEEAYEGQTALNIAIERRQGDIAALLIAAGADVNAHAKGAFFNPKYQHEGFYF 262
Query: 163 GEHPLSFAACVGSEEIVRLLIEH-GADIRAQDSLGNTVLHILI-----LQPNKTFACQMY 216
GE PL+ AAC EIV+LL+EH DI ++DS GN +LH L+ + F +MY
Sbjct: 263 GETPLALAACTNQPEIVQLLMEHEQTDITSRDSRGNNILHALVTVAEDFKTQNDFVKRMY 322
Query: 217 NLLLSYDEHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQK-----------RKH 265
+++L + + LE N+ GLTP +LA G + ++++ + RK
Sbjct: 323 DMILLRSGNWE----LETTRNNDGLTPLQLAAKMGKAEILKYILSREIKEKRLRSLSRKF 378
Query: 266 VQWTCGPLTSTLYDLTEIDSWGEELSFLELVVSSKKREAR-QILEQTPVKELVSFKWKKY 324
W GP++S+LYDLT +D+ + S LE+ V + + R ++L P+ L+ KWKK+
Sbjct: 379 TDWAYGPVSSSLYDLTNVDTTTD-NSVLEITVYNTNIDNRHEMLTLEPLHTLLHMKWKKF 437
Query: 325 GRPYFCVLASLYILYMICFTTCCIYRPLKLRDDNRTDPRDITILQQKLLQEAYVTHQDN- 383
+ F + Y Y I T YRP + ++ + +TH+
Sbjct: 438 AKHMFFLSFCFYFFYNITLTLVSYYRPRE---------------EEAIPHPLALTHKMGW 482
Query: 384 IRLVGELVTVTGAVIILLLEIPDIFRVGASRYFGQTILGGP-FHVIIITYASLVLLTMVM 442
++L+G + + A+ I + E IF + S Q+IL FH + A LV+L++ +
Sbjct: 483 LQLLGRMFVLIWAMCISVKEGIAIFLLRPSDL--QSILSDAWFHFVFFIQAVLVILSVFL 540
Query: 443 RLTNMNGEVVPLSFALVLGWCSVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVIL 502
L + L A+ LGW +++Y+ RGFQ +G +++MIQK+I D+++F ++ V +L
Sbjct: 541 YLFAYKEYLACLVLAMALGWANMLYYTRGFQSMGMYSVMIQKVILHDVLKFLFVYIVFLL 600
Query: 503 GFASAFHITFQT--EDPNNLGEFSDYPTALFSTFELFLTIIDGPANYSVDLPFMYCITYA 560
GF A + +D + + + A+ F+L + + D + P ++
Sbjct: 601 GFGVALASLIEKCPKDNKDCSSYGSFSDAVLELFKLTIGLGDLNIQQNSKYPILFLFLLI 660
Query: 561 AFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVATTVMLERKMPRFLWPRSGICG 620
+ I+ +L+LN+ IA+MG+T V++E + +WR Q T + E+ +P +L R +
Sbjct: 661 TYVILTFVLLLNMLIALMGETVENVSKESERIWRLQRARTILEFEKMLPEWLRSRFRMGE 720
Query: 621 YEYGLGD--RWFLRVEN 635
D R LR+
Sbjct: 721 LCKVAEDDFRLCLRINE 737
>6OO7-A nrPDB
Length = 786
Score = 548 bits (1413), Expect = e-156, Method: Composition-based stats.
Identities = 173/634 (27%), Positives = 294/634 (46%), Gaps = 74/634 (11%)
Query: 55 ENDLRLLKILLLNQSCDFQQRGAVGETALHVAALY--DNLEAATLLMEAAPELAKEPA-- 110
L L+ + G+ G+T L A L D + A + + P
Sbjct: 91 AGLLEYLRRTSKYLTDSEYTEGSTGKTCLMKAVLNLQDGVNACIQPLLEIDRDSGNPQPL 150
Query: 111 -----LCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEH 165
E + G +ALHIA+ ++L V+ L+ GA+V A+A G F+++ Y+GE
Sbjct: 151 VNAQCTDEYYRGHSALHIAIEKRSLQCVKLLVENGANVHAKACGHFFQKNQDTCFYFGEL 210
Query: 166 PLSFAACVGSEEIVRLLIEHG---ADIRAQDSLGNTVLHILIL-----QPNKTFACQMYN 217
PLS AAC ++V L+E+ A ++AQDSLGNTVLH L++ N +MY+
Sbjct: 211 PLSLAACTKQWDVVNYLLENPHQPASLQAQDSLGNTVLHALVMIADDSAENSALVVRMYD 270
Query: 218 LLLSYDEHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQK----------RKHVQ 267
LL LE +PN +GLTP KLA EG +F+H++Q+ RK +
Sbjct: 271 GLLQAGARLCPNVQLEGIPNLEGLTPLKLAAKEGKIEIFKHILQREFSAPCQSLSRKFTE 330
Query: 268 WTCGPLTSTLYDLTEIDSWGEELSFLELVVS-SKKREARQILEQTPVKELVSFKWKKYGR 326
W GP+ +LYDL +DSW EE S LE++ S+ +++ P+ +L+ KW +
Sbjct: 331 WCYGPVRVSLYDLASVDSW-EENSVLEIIAFHSRSPHRHRMVVLEPLNKLLQAKWDRL-I 388
Query: 327 PYFCVLASLYILYMICFTTCCIYRPLKLRDDNRTDPRDITILQQKLLQEAYVTHQDNIRL 386
P FC Y++YM+ FT ++P L+++ T +++ L
Sbjct: 389 PRFCFNFLCYLVYMLIFTAVAYHQP---------------ALEKQGFPPLKATAGNSMLL 433
Query: 387 VGELVTVTGAVIILLLEIPDIFRVGASRYFGQTILGGPFHVIIITYASLVLLTMVMRLTN 446
+G ++ + G V +LL ++ +R + + + ++ + A L +L+ V+
Sbjct: 434 LGHILILLGGVYLLLGQLWYFWRRR--LFIWISFMDSYSEILFLLQALLTVLSQVLCFLA 491
Query: 447 MNGEVVPLSFALVLGWCSVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFAS 506
+ + L +L +GW +++Y+ RGFQ G +++MI+K+I DL+RF + V + GFA
Sbjct: 492 IEWYLPLLVSSLAMGWTNLLYYTRGFQHTGIYSVMIEKVILRDLLRFLLVYLVFLFGFAV 551
Query: 507 AF-HITFQTEDPNNLG----------------EFSDYPTALFSTFELF-LTIIDGPANYS 548
A ++ + ++ E Y + L ++ ELF TI G +
Sbjct: 552 ALVSLSREAQNSRTPAGPNATEVGQPGAGQEDEAPPYRSILDASLELFKFTIGMGELAFQ 611
Query: 549 VDLPFMY--CITYAAFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVATTVMLER 606
L F + A+ ++ +L+LN+ IA+M +T VA + +W+ Q + + +E
Sbjct: 612 EQLRFRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNSVATDSWSIWKLQKAISVLEMEN 671
Query: 607 KMPRFLWP--RSG----ICGYEYGLGD-RWFLRV 633
R+G + G D RW RV
Sbjct: 672 GYWWCRRKKQRAGVMLTVGTRPDGSPDERWCFRV 705
>5AN8-A nrPDB
Length = 613
Score = 541 bits (1393), Expect = e-154, Method: Composition-based stats.
Identities = 178/617 (28%), Positives = 295/617 (47%), Gaps = 60/617 (9%)
Query: 55 ENDLRLLKILLLNQSCDFQQRGAVGETALHVAAL--YDNLEAATLLMEAAPELAKEPA-- 110
L L+ + G+ G+T L A L D + A + + P
Sbjct: 16 AGLLEYLRRTSKYLTDSEYTEGSTGKTCLMKAVLNLQDGVNACIQPLLEIDRDSGNPQPL 75
Query: 111 -----LCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEH 165
E + G +ALHIA+ ++L V+ L+ GA+V A+A G F+++ Y+GE
Sbjct: 76 VNAQCTDEYYRGHSALHIAIEKRSLQCVKLLVENGANVHAKACGHFFQKNQDTCFYFGEL 135
Query: 166 PLSFAACVGSEEIVRLLIEHG---ADIRAQDSLGNTVLHILIL-----QPNKTFACQMYN 217
PLS AAC ++V L+E+ A ++AQDSLGNTVLH L++ N +MY+
Sbjct: 136 PLSLAACTKQWDVVNYLLENPHPAASLQAQDSLGNTVLHALVMIADNSPENSALVVRMYD 195
Query: 218 LLLSYDEHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQK----------RKHVQ 267
LL LE +PN +GLTP KLA EG +F+H++Q+ RK +
Sbjct: 196 GLLQAGARLCPNVQLEGIPNLEGLTPLKLAAKEGKIEIFKHILQREFSAPCQSLSRKFTE 255
Query: 268 WTCGPLTSTLYDLTEIDSWGEELSFLELVVS-SKKREARQILEQTPVKELVSFKWKKYGR 326
W GP+ +LYDL +DSW EE S LE++ S+ +++ P+ +L+ KW +
Sbjct: 256 WCYGPVRVSLYDLASVDSW-EENSVLEIIAFHSRSPHRHRMVVLEPLNKLLQAKWDRL-I 313
Query: 327 PYFCVLASLYILYMICFTTCCIYRPLKLRDDNRTDPRDITILQQKLLQEAYVTHQDNIRL 386
P FC Y++YM+ FT ++P L+++ T +++ L
Sbjct: 314 PRFCFNFLCYLVYMLIFTAVAYHQP---------------ALEKQGFPPLKATAGNSMLL 358
Query: 387 VGELVTVTGAVIILLLEIPDIFRVGASRYFGQTILGGPFHVIIITYASLVLLTMVMRLTN 446
+G ++ + G V +LL ++ +R + + + F ++ + A L +L+ V+
Sbjct: 359 LGHILILLGGVYLLLGQLWYFWRRR--LFIWISFMDSYFEILFLLQALLTVLSQVLCFLA 416
Query: 447 MNGEVVPLSFALVLGWCSVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFAS 506
+ + L +LVLGW +++Y+ RGFQ G +++MIQK+I DL+RF + V + GFA
Sbjct: 417 IEWYLPLLVSSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAV 476
Query: 507 AFHITFQTEDPNNLGEFSDYPTALFSTFELF-LTIIDGPANYSVDLPFMY--CITYAAFA 563
A ++ E + E Y + L ++ ELF TI G + L F + A+
Sbjct: 477 AL-VSLSREAQED--EAPPYRSILDASLELFKFTIGMGELAFQEQLRFRGVVLLLLLAYV 533
Query: 564 IIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVATTVMLERKMPRFLWP--RSG---- 617
++ +L+LN+ IA+M +T VA + +W+ Q + + +E R+G
Sbjct: 534 LLTYVLLLNMLIALMSETVNSVATDSWSIWKLQKAISVLEMENGYWWCRRKKQRAGVMLT 593
Query: 618 ICGYEYGLGD-RWFLRV 633
+ G D RW RV
Sbjct: 594 VGTRPDGSPDERWCFRV 610
>5HI9-A nrPDB
Length = 770
Score = 531 bits (1368), Expect = e-151, Method: Composition-based stats.
Identities = 176/622 (28%), Positives = 285/622 (45%), Gaps = 78/622 (12%)
Query: 71 DFQQRGAVGETALHVAALY--DNLEAATLLMEAAPELAKEPA-------LCEPFVGQTAL 121
G+ G+T L A L D + A + + + + P E + G +AL
Sbjct: 109 SAYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKPLVNAQCTDEFYQGHSAL 168
Query: 122 HIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRL 181
HIA+ ++L V+ L+ GA V RA G F++ Y+GE PLS AAC ++V
Sbjct: 169 HIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTY 228
Query: 182 LIEHG---ADIRAQDSLGNTVLHILIL-----QPNKTFACQMYNLLLSYDEHSDHLQSLE 233
L+E+ A + A DSLGNTVLH L++ N MY+ LL LE
Sbjct: 229 LLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLE 288
Query: 234 LVPNHQGLTPFKLAGVEGNTVMFQHLMQK----------RKHVQWTCGPLTSTLYDLTEI 283
+ NHQGLTP KLA EG +F+H++Q+ RK +W GP+ +LYDL+ +
Sbjct: 289 EISNHQGLTPLKLAAKEGKIEIFRHILQREFSGPYQPLSRKFTEWCYGPVRVSLYDLSSV 348
Query: 284 DSWGEELSFLELVV---SSKKREARQILEQTPVKELVSFKWKKYGRPYFCVLASLYILYM 340
DSW E+ S LE++ S R +L P+ +L+ KW + F + Y++YM
Sbjct: 349 DSW-EKNSVLEIIAFHCKSPNRHRMVVL--EPLNKLLQEKWDRLVSR-FFFNFACYLVYM 404
Query: 341 ICFTTCCIYRPLKLRDDNRTDPRDITILQQKLLQEAYVTHQDNIRLVGELVTVTGAVIIL 400
FT ++P L Q + + T +++ L+G ++ + G + +L
Sbjct: 405 FIFTVVAYHQP---------------SLDQPAIPSSKATFGESMLLLGHILILLGGIYLL 449
Query: 401 LLEIPDIFRVGASRYFGQTILGGPFHVIIITYASLVLLTMVMRLTNMNGEVVPLSFALVL 460
L ++ +R + + + F ++ + A L +L+ V+R + L +LVL
Sbjct: 450 LGQLWYFWRRR--LFIWISFMDSYFEILFLLQALLTVLSQVLRFMETEWYLPLLVLSLVL 507
Query: 461 GWCSVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAF-HITFQTEDPNN 519
GW +++Y+ RGFQ G +++MIQK+I DL+RF + V + GFA A ++ + P
Sbjct: 508 GWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVSLSREARSPKA 567
Query: 520 LGEFS----------------DYPTALFSTFELF-LTIIDGPANYSVDLPFMY--CITYA 560
+ + Y + L ++ ELF TI G + L F +
Sbjct: 568 PEDNNSTVTEQPTVGQEEEPAPYRSILDASLELFKFTIGMGELAFQEQLRFRGVVLLLLL 627
Query: 561 AFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVATTVMLERKMPRFLWP--RSG- 617
A+ ++ +L+LN+ IA+M +T VA +W+ Q + + +E R G
Sbjct: 628 AYVLLTYVLLLNMLIALMSETVNHVADNSWSIWKLQKAISVLEMENGYWWCRRKKHREGR 687
Query: 618 ---ICGYEYGLGD-RWFLRVEN 635
+ G D RW RVE
Sbjct: 688 LLKVGTRGDGTPDERWCFRVEE 709
>6BO5-A nrPDB
Length = 695
Score = 526 bits (1354), Expect = e-149, Method: Composition-based stats.
Identities = 176/622 (28%), Positives = 285/622 (45%), Gaps = 78/622 (12%)
Query: 71 DFQQRGAVGETALHVAAL--YDNLEAATLLMEAAPELAKEPA-------LCEPFVGQTAL 121
G+ G+T L A L D + A + + + + P E + G +AL
Sbjct: 69 SAYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKPLVNAQCTDEFYQGHSAL 128
Query: 122 HIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRL 181
HIA+ ++L V+ L+ GA V RA G F++ Y+GE PLS AAC ++V
Sbjct: 129 HIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTY 188
Query: 182 LIEHG---ADIRAQDSLGNTVLHILIL-----QPNKTFACQMYNLLLSYDEHSDHLQSLE 233
L+E+ A + A DSLGNTVLH L++ N MY+ LL LE
Sbjct: 189 LLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLE 248
Query: 234 LVPNHQGLTPFKLAGVEGNTVMFQHLMQK----------RKHVQWTCGPLTSTLYDLTEI 283
+ NHQGLTP KLA EG +F+H++Q+ RK +W GP+ +LYDL+ +
Sbjct: 249 EISNHQGLTPLKLAAKEGKIEIFRHILQREFSGPYQPLSRKFTEWCYGPVRVSLYDLSSV 308
Query: 284 DSWGEELSFLELVV---SSKKREARQILEQTPVKELVSFKWKKYGRPYFCVLASLYILYM 340
DSW E+ S LE++ S R +L P+ +L+ KW + F + Y++YM
Sbjct: 309 DSW-EKNSVLEIIAFHCKSPNRHRMVVL--EPLNKLLQEKWDRLVSR-FFFNFACYLVYM 364
Query: 341 ICFTTCCIYRPLKLRDDNRTDPRDITILQQKLLQEAYVTHQDNIRLVGELVTVTGAVIIL 400
FT ++P L Q + + T +++ L+G ++ + G + +L
Sbjct: 365 FIFTVVAYHQP---------------SLDQPAIPSSKATFGESMLLLGHILILLGGIYLL 409
Query: 401 LLEIPDIFRVGASRYFGQTILGGPFHVIIITYASLVLLTMVMRLTNMNGEVVPLSFALVL 460
L ++ +R + + + F ++ + A L +L+ V+R + L +LVL
Sbjct: 410 LGQLWYFWRRR--LFIWISFMDSYFEILFLLQALLTVLSQVLRFMETEWYLPLLVLSLVL 467
Query: 461 GWCSVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAF-HITFQTEDPNN 519
GW +++Y+ RGFQ G +++MIQK+I DL+RF + V + GFA A ++ + P
Sbjct: 468 GWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVSLSREARSPKA 527
Query: 520 LGEFS----------------DYPTALFSTFELF-LTIIDGPANYSVDLPFMY--CITYA 560
+ + Y + L ++ ELF TI G + L F +
Sbjct: 528 PEDNNSTVTEQPTVGQEEEPAPYRSILDASLELFKFTIGMGELAFQEQLRFRGVVLLLLL 587
Query: 561 AFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVATTVMLERKMPRFLWP--RSG- 617
A+ ++ +L+LN+ IA+M +T VA +W+ Q + + +E R G
Sbjct: 588 AYVLLTYVLLLNMLIALMSETVNHVADNSWSIWKLQKAISVLEMENGYWWCRRKKHREGR 647
Query: 618 ---ICGYEYGLGD-RWFLRVEN 635
+ G D RW RVE
Sbjct: 648 LLKVGTRGDGTPDERWCFRVEE 669
>2RFA-A nrPDB
Length = 232
Score = 288 bits (736), Expect = 7e-78, Method: Composition-based stats.
Identities = 181/221 (81%), Positives = 195/221 (88%), Gaps = 1/221 (0%)
Query: 44 IRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAP 103
I +SPLL AAKEND++ L LL + C+ QRGA+GETALH+AALYDNLEAA +LMEAAP
Sbjct: 2 IWESPLLLAAKENDVQALSKLLKFEGCEVHQRGAMGETALHIAALYDNLEAAMVLMEAAP 61
Query: 104 ELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYG 163
EL EP E + GQTALHIAV+NQN+NLVRALLARGASVSARATG+ F PHNLIYYG
Sbjct: 62 ELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYG 121
Query: 164 EHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD 223
EHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD
Sbjct: 122 EHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD 181
Query: 224 EHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRK 264
DHL+SLELVPN+QGLTPFKLAGVEGN VMFQHLMQKRK
Sbjct: 182 G-GDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKRK 221
>2ETB-A nrPDB
Length = 256
Score = 223 bits (568), Expect = 3e-58, Method: Composition-based stats.
Identities = 72/210 (34%), Positives = 103/210 (49%), Gaps = 17/210 (8%)
Query: 71 DFQQRGAVGETALHVAAL--YDNLEAATLLMEAAPELAKEPA-------LCEPFVGQTAL 121
G+ G+T L A L D + A + + + + P E + G +AL
Sbjct: 35 SAYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKPLVNAQCTDEFYQGHSAL 94
Query: 122 HIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRL 181
HIA+ ++L V+ L+ GA V RA G F++ Y+GE PLS AAC ++V
Sbjct: 95 HIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTY 154
Query: 182 LIEH---GADIRAQDSLGNTVLHILIL-----QPNKTFACQMYNLLLSYDEHSDHLQSLE 233
L+E+ A + A DSLGNTVLH L++ N MY+ LL LE
Sbjct: 155 LLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLE 214
Query: 234 LVPNHQGLTPFKLAGVEGNTVMFQHLMQKR 263
+ NHQGLTP KLA EG +F+H++Q+
Sbjct: 215 EISNHQGLTPLKLAAKEGKIEIFRHILQRE 244
>2F37-A nrPDB
Length = 251
Score = 221 bits (564), Expect = 7e-58, Method: Composition-based stats.
Identities = 70/226 (30%), Positives = 105/226 (46%), Gaps = 17/226 (7%)
Query: 55 ENDLRLLKILLLNQSCDFQQRGAVGETALHVAALY--DNLEAATLLMEAAPELAKEPA-- 110
L + G+ G+T L A L D + A L + + P
Sbjct: 24 AGLPEYLSKTSKYLTDSEYTEGSTGKTCLMKAVLNLKDGVNACILPLLQIDRDSGNPQPL 83
Query: 111 -----LCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEH 165
+ + G +ALHIA+ ++L V+ L+ GA+V ARA G F++ Y+GE
Sbjct: 84 VNAQCTDDYYRGHSALHIAIEKRSLQCVKLLVENGANVHARACGRFFQKGQGTCFYFGEL 143
Query: 166 PLSFAACVGSEEIVRLLIEH---GADIRAQDSLGNTVLHILILQPNKT-----FACQMYN 217
PLS AAC ++V L+E+ A ++A DS GNTVLH L++ + + MY+
Sbjct: 144 PLSLAACTKQWDVVSYLLENPHQPASLQATDSQGNTVLHALVMISDNSAENIALVTSMYD 203
Query: 218 LLLSYDEHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKR 263
LL LE + N Q LTP KLA EG +F+H++Q+
Sbjct: 204 GLLQAGARLCPTVQLEDIRNLQDLTPLKLAAKEGKIEIFRHILQRE 249
>3W9G-A nrPDB
Length = 260
Score = 197 bits (501), Expect = 1e-50, Method: Composition-based stats.
Identities = 70/205 (34%), Positives = 102/205 (49%), Gaps = 18/205 (8%)
Query: 77 AVGETALHVAALY---DNLEAATLLME------AAPELAKEPALCEPFVGQTALHIAVMN 127
+ G+T L A L + +L++ E P + GQTALHIA+
Sbjct: 44 STGKTCLPKALLNLSAGRNDTIPILLDIAEKTGNMREFINSPFRDVYYRGQTALHIAIER 103
Query: 128 QNLNLVRALLARGASVSARATGAAFR-RSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHG 186
+ + V L+ +GA V A+A G F+ + Y+GE PLS AAC IV L E+G
Sbjct: 104 RCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHIVHYLTENG 163
Query: 187 ---ADIRAQDSLGNTVLHILI-----LQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNH 238
AD+R QDS GNTVLH L+ + N F +MY+LLL +LE + N+
Sbjct: 164 HKQADLRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLIKCAKLFPDTNLEALLNN 223
Query: 239 QGLTPFKLAGVEGNTVMFQHLMQKR 263
GL+P +A G +FQH++++
Sbjct: 224 DGLSPLMMAAKTGKIGIFQHIIRRE 248
>4DX2-A nrPDB
Length = 259
Score = 196 bits (499), Expect = 2e-50, Method: Composition-based stats.
Identities = 71/205 (34%), Positives = 102/205 (49%), Gaps = 18/205 (8%)
Query: 77 AVGETALHVAALY---DNLEAATLLME------AAPELAKEPALCEPFVGQTALHIAVMN 127
+ G+T L A L + +L++ E P + GQTALHIA+
Sbjct: 42 STGKTCLPKALLNLSNGRNDTIPVLLDIAERTGNMREFINSPFRDIYYRGQTALHIAIER 101
Query: 128 QNLNLVRALLARGASVSARATGAAFR-RSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHG 186
+ + V L+A+GA V A+A G F+ + Y+GE PLS AAC IV L E+
Sbjct: 102 RCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHIVNYLTENP 161
Query: 187 ---ADIRAQDSLGNTVLHILI-----LQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNH 238
AD+R QDS GNTVLH L+ + N F +MY+LLL +LE V N+
Sbjct: 162 HKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLLKCARLFPDSNLEAVLNN 221
Query: 239 QGLTPFKLAGVEGNTVMFQHLMQKR 263
GL+P +A G +FQH++++
Sbjct: 222 DGLSPLMMAAKTGKIGIFQHIIRRE 246
>5H76-A nrPDB
Length = 201
Score = 195 bits (496), Expect = 5e-50, Method: Composition-based stats.
Identities = 59/201 (29%), Positives = 89/201 (44%), Gaps = 26/201 (12%)
Query: 47 SPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELA 106
LL+AA+ ++IL+ N D G T LH+AA +LE +L++ ++
Sbjct: 8 RKLLEAARAGQDDEVRILMAN-GADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVD 66
Query: 107 KEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHP 166
G T LH+A +L +V LL GA V+A + G P
Sbjct: 67 -----ASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSD-------------GMTP 108
Query: 167 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFA--CQMYNLL----L 220
L AA G EIV +L++HGA + AQD G T I I N+ A Y +L L
Sbjct: 109 LHLAAKWGYLEIVEVLLKHGA-VNAQDKFGKTAFDISIDNGNEDLAQILAFYEILHLPNL 167
Query: 221 SYDEHSDHLQSLELVPNHQGL 241
+ ++ + +QSL+ P+
Sbjct: 168 NEEQRNAFIQSLKDDPSQSAN 188
Score = 127 bits (318), Expect = 2e-29, Method: Composition-based stats.
Identities = 43/173 (24%), Positives = 67/173 (38%), Gaps = 26/173 (15%)
Query: 121 LHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVR 180
L A + VR L+A GA V+A G PL AA G EIV
Sbjct: 10 LLEAARAGQDDEVRILMANGADVNAADNT-------------GTTPLHLAAYSGHLEIVE 56
Query: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQG 240
+L++HGAD+ A D G T LH+ + ++ +LL + + S G
Sbjct: 57 VLLKHGADVDASDVFGYTPLHLAAYWGH----LEIVEVLLKNGADVNAMDS-------DG 105
Query: 241 LTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSWGEELSFL 293
+TP LA G + + L++ T +D++ + + L
Sbjct: 106 MTPLHLAAKWGYLEIVEVLLKHGAVN--AQDKFGKTAFDISIDNGNEDLAQIL 156
Score = 54.0 bits (128), Expect = 3e-07, Method: Composition-based stats.
Identities = 31/159 (19%), Positives = 49/159 (30%), Gaps = 57/159 (35%)
Query: 167 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHS 226
L AA G ++ VR+L+ +GAD+ A D
Sbjct: 10 LLEAARAGQDDEVRILMANGADVNAAD--------------------------------- 36
Query: 227 DHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQWT----CGPLTSTLYDLTE 282
+ G TP LA G+ + + L++ V + PL Y
Sbjct: 37 -----------NTGTTPLHLAAYSGHLEIVEVLLKHGADVDASDVFGYTPLHLAAY---- 81
Query: 283 IDSWGEELSFLELVVSSKKREARQILEQTPVKELVSFKW 321
WG L+ + A TP+ ++ KW
Sbjct: 82 ---WGHLEIVEVLLKNGADVNAMDSDGMTPLH--LAAKW 115
>6MWQ-A nrPDB
Length = 493
Score = 195 bits (495), Expect = 6e-50, Method: Composition-based stats.
Identities = 57/179 (31%), Positives = 80/179 (44%), Gaps = 19/179 (10%)
Query: 47 SPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELA 106
LL+AA+ ++IL+ N D G T LH+AA +LE +L++ ++
Sbjct: 7 KKLLEAARAGQDDEVRILMAN-GADVNALDRFGLTPLHLAAQRGHLEIVEVLLKCGADVN 65
Query: 107 KEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHP 166
GQT LH+A +L +V LL GA V+A G+ P
Sbjct: 66 -----AADLWGQTPLHLAATAGHLEIVEVLLKYGADVNALD-------------LIGKTP 107
Query: 167 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEH 225
L A G EIV +L++HGAD+ AQD G T I I N+ A + L LS H
Sbjct: 108 LHLTAIDGHLEIVEVLLKHGADVNAQDKFGKTAFDISIDNGNEDLAEILQKLNLSDIAH 166
Score = 134 bits (337), Expect = 1e-31, Method: Composition-based stats.
Identities = 44/184 (23%), Positives = 73/184 (39%), Gaps = 25/184 (13%)
Query: 121 LHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVR 180
L A + VR L+A GA V+A +G PL AA G EIV
Sbjct: 9 LLEAARAGQDDEVRILMANGADVNALDR-------------FGLTPLHLAAQRGHLEIVE 55
Query: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQG 240
+L++ GAD+ A D G T LH+ + ++ +LL Y + L + G
Sbjct: 56 VLLKCGADVNAADLWGQTPLHLAATAGH----LEIVEVLLKYGADVNALDLI-------G 104
Query: 241 LTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSWGEELSFLELVVSSK 300
TP L ++G+ + + L++ V T +D++ + + L+ + S
Sbjct: 105 KTPLHLTAIDGHLEIVEVLLKHGADVN-AQDKFGKTAFDISIDNGNEDLAEILQKLNLSD 163
Query: 301 KREA 304
Sbjct: 164 IAHR 167
Score = 84.8 bits (208), Expect = 1e-16, Method: Composition-based stats.
Identities = 24/93 (25%), Positives = 44/93 (47%), Gaps = 6/93 (6%)
Query: 46 DSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPEL 105
+PL AA L ++++LL D +G+T LH+ A+ +LE +L++ ++
Sbjct: 72 QTPLHLAATAGHLEIVEVLLKY-GADVNALDLIGKTPLHLTAIDGHLEIVEVLLKHGADV 130
Query: 106 AKEPALCEPFVGQTALHIAVMNQNLNLVRALLA 138
+ G+TA I++ N N +L L
Sbjct: 131 NAQDKF-----GKTAFDISIDNGNEDLAEILQK 158
Score = 55.1 bits (131), Expect = 1e-07, Method: Composition-based stats.
Identities = 28/148 (18%), Positives = 45/148 (30%), Gaps = 47/148 (31%)
Query: 167 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHS 226
L AA G ++ VR+L+ +GAD+ A D
Sbjct: 9 LLEAARAGQDDEVRILMANGADVNALDRF------------------------------- 37
Query: 227 DHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSW 286
GLTP LA G+ + + L++ V T L
Sbjct: 38 -------------GLTPLHLAAQRGHLEIVEVLLKCGADVNAA-DLWGQTPLHLAATAGH 83
Query: 287 GEELSFLELVVSSKKREARQILEQTPVK 314
E + L + A ++ +TP+
Sbjct: 84 LEIVEVL--LKYGADVNALDLIGKTPLH 109
>5AQ9-A nrPDB
Length = 422
Score = 193 bits (490), Expect = 2e-49, Method: Composition-based stats.
Identities = 50/170 (29%), Positives = 73/170 (42%), Gaps = 19/170 (11%)
Query: 47 SPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELA 106
LL+AA+ ++IL+ N D G T LH+AA +LE +L++ ++
Sbjct: 16 RKLLEAARAGQDDEVRILMAN-GADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVD 74
Query: 107 KEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHP 166
G T LH+A +L +V LL GA V+A + G P
Sbjct: 75 -----ASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSD-------------GMTP 116
Query: 167 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMY 216
L AA G EIV +L++HGAD+ AQD G T + N +
Sbjct: 117 LHLAAKWGYLEIVEVLLKHGADVNAQDKFGKTPFDLADDNGNDDVGTLLQ 166
Score = 152 bits (384), Expect = 5e-37, Method: Composition-based stats.
Identities = 47/186 (25%), Positives = 76/186 (40%), Gaps = 25/186 (13%)
Query: 121 LHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVR 180
L A + VR L+A GA V+A G PL AA G EIV
Sbjct: 18 LLEAARAGQDDEVRILMANGADVNAADNT-------------GTTPLHLAAYSGHLEIVE 64
Query: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQG 240
+L++HGAD+ A D G T LH+ + ++ +LL + + S G
Sbjct: 65 VLLKHGADVDASDVFGYTPLHLAAYWGH----LEIVEVLLKNGADVNAMDS-------DG 113
Query: 241 LTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSWGEELSFLELVVSSK 300
+TP LA G + + L++ V T +DL + + + + L++ ++
Sbjct: 114 MTPLHLAAKWGYLEIVEVLLKHGADVN-AQDKFGKTPFDLADDNGNDDVGTLLQVAAAAD 172
Query: 301 KREARQ 306
+ AR
Sbjct: 173 QLGARV 178
Score = 45.5 bits (106), Expect = 8e-05, Method: Composition-based stats.
Identities = 18/57 (31%), Positives = 27/57 (47%), Gaps = 1/57 (1%)
Query: 47 SPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAP 103
+PL AAK L ++++LL D + G+T +A N + TLL AA
Sbjct: 115 TPLHLAAKWGYLEIVEVLLK-HGADVNAQDKFGKTPFDLADDNGNDDVGTLLQVAAA 170
>4N5Q-A nrPDB
Length = 257
Score = 193 bits (489), Expect = 4e-49, Method: Composition-based stats.
Identities = 71/249 (28%), Positives = 112/249 (44%), Gaps = 35/249 (14%)
Query: 46 DSPLLQAAKENDLRLLKILLL--------NQSCDFQQ-------RGAVGETALHVAALY- 89
+ A E + L+ LL + D G+T L A L
Sbjct: 4 KKRIFAAVSEGCVEELRELLQDLQDLCRRRRGLDVPDFLMHKLTASDTGKTCLMKALLNI 63
Query: 90 --DNLEAATLLMEAAPELAKEPA------LCEPFVGQTALHIAVMNQNLNLVRALLARGA 141
+ E +L+ A E E + GQTAL+IA+ + ++ L+A GA
Sbjct: 64 NPNTKEIVRILLAFAEENDILDRFINAEYTEEAYEGQTALNIAIERRQGDITAVLIAAGA 123
Query: 142 SVSARATGAAFR-RSPHNLIYYGEHPLSFAACVGSEEIVRLLIEH-GADIRAQDSLGNTV 199
V+A A G F + H Y+GE PL+ AAC EIV+LL+E+ DI +QDS GN +
Sbjct: 124 DVNAHAKGVFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMENEQTDITSQDSRGNNI 183
Query: 200 LHILI-----LQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQGLTPFKLAGVEGNTV 254
LH L+ + F +MY+++L + + LE + N+ GLTP +LA G
Sbjct: 184 LHALVTVAEDFKTQNDFVKRMYDMILLRSGNWE----LETMRNNDGLTPLQLAAKMGKAE 239
Query: 255 MFQHLMQKR 263
+ ++++ +
Sbjct: 240 ILKYILSRE 248
>5AQA-A nrPDB
Length = 418
Score = 192 bits (487), Expect = 5e-49, Method: Composition-based stats.
Identities = 54/198 (27%), Positives = 85/198 (42%), Gaps = 24/198 (12%)
Query: 47 SPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELA 106
LL+AA+ ++IL+ N D G T LH+AA +LE +L++ ++
Sbjct: 16 RKLLEAARAGQDDEVRILMAN-GADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVD 74
Query: 107 KEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHP 166
G T LH+A +L +V LL GA V+A + G P
Sbjct: 75 -----ASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSD-------------GMTP 116
Query: 167 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSY---- 222
L AA G +EIV +L++ GAD+ AQD G L + Q + A ++ L
Sbjct: 117 LHLAAKWGYKEIVEVLLKAGADVDAQDKFGKRPLWLAADQGHAEIAAKLVAARLKARVGY 176
Query: 223 -DEHSDHLQSLELVPNHQ 239
+ + + LE V + +
Sbjct: 177 IELDLNSGKILESVRSEE 194
Score = 119 bits (298), Expect = 5e-27, Method: Composition-based stats.
Identities = 44/173 (25%), Positives = 64/173 (36%), Gaps = 25/173 (14%)
Query: 121 LHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVR 180
L A + VR L+A GA V+A G PL AA G EIV
Sbjct: 18 LLEAARAGQDDEVRILMANGADVNAADNT-------------GTTPLHLAAYSGHLEIVE 64
Query: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQG 240
+L++HGAD+ A D G T LH+ + ++ +LL + + S G
Sbjct: 65 VLLKHGADVDASDVFGYTPLHLAAYWGH----LEIVEVLLKNGADVNAMDS-------DG 113
Query: 241 LTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSWGEELSFL 293
+TP LA G + + L++ V L E + L
Sbjct: 114 MTPLHLAAKWGYKEIVEVLLKAGADVD-AQDKFGKRPLWLAADQGHAEIAAKL 165
Score = 54.0 bits (128), Expect = 2e-07, Method: Composition-based stats.
Identities = 31/159 (19%), Positives = 49/159 (30%), Gaps = 57/159 (35%)
Query: 167 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHS 226
L AA G ++ VR+L+ +GAD+ A D
Sbjct: 18 LLEAARAGQDDEVRILMANGADVNAAD--------------------------------- 44
Query: 227 DHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQWT----CGPLTSTLYDLTE 282
+ G TP LA G+ + + L++ V + PL Y
Sbjct: 45 -----------NTGTTPLHLAAYSGHLEIVEVLLKHGADVDASDVFGYTPLHLAAY---- 89
Query: 283 IDSWGEELSFLELVVSSKKREARQILEQTPVKELVSFKW 321
WG L+ + A TP+ ++ KW
Sbjct: 90 ---WGHLEIVEVLLKNGADVNAMDSDGMTPLH--LAAKW 123
>5MIO-C nrPDB
Length = 573
Score = 189 bits (480), Expect = 4e-48, Method: Composition-based stats.
Identities = 54/174 (31%), Positives = 84/174 (48%), Gaps = 19/174 (10%)
Query: 47 SPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELA 106
LL+AA+ +++L+ N D A G T LH+AA Y +LE +L++ +++
Sbjct: 412 KKLLEAARAGQDDEVRVLMAN-GADVNATDASGLTPLHLAATYGHLEIVEVLLKHGADVS 470
Query: 107 KEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHP 166
+G T LH+A + +L +V LL GA V+A T +G+ P
Sbjct: 471 -----ASDLMGSTPLHLAALIGHLEIVEVLLKHGADVNAVDT-------------WGDTP 512
Query: 167 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLL 220
L AA +G +IV L++HGAD+ AQD G T I ++ A + L L
Sbjct: 513 LRLAAVMGHLKIVEALLKHGADVNAQDKFGKTAYDTSIDNGSEDLAEILQKLNL 566
Score = 142 bits (357), Expect = 6e-34, Method: Composition-based stats.
Identities = 50/171 (29%), Positives = 77/171 (45%), Gaps = 26/171 (15%)
Query: 121 LHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVR 180
L A + VR L+A GA V+A G PL AA G EIV
Sbjct: 414 LLEAARAGQDDEVRVLMANGADVNATDAS-------------GLTPLHLAATYGHLEIVE 460
Query: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQG 240
+L++HGAD+ A D +G+T LH+ L + ++ +LL + + + + G
Sbjct: 461 VLLKHGADVSASDLMGSTPLHLAALIGH----LEIVEVLLKHGADVNAVDTW-------G 509
Query: 241 LTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSWGEELS 291
TP +LA V G+ + + L++ V T YD T ID+ E+L+
Sbjct: 510 DTPLRLAAVMGHLKIVEALLKHGADVN-AQDKFGKTAYD-TSIDNGSEDLA 558
Score = 38.2 bits (87), Expect = 0.015, Method: Composition-based stats.
Identities = 14/55 (25%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Query: 46 DSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLME 100
D+PL AA L++++ LL D + G+TA + + + A +L +
Sbjct: 510 DTPLRLAAVMGHLKIVEALLK-HGADVNAQDKFGKTAYDTSIDNGSEDLAEILQK 563
>2NYJ-A nrPDB
Length = 273
Score = 187 bits (475), Expect = 1e-47, Method: Composition-based stats.
Identities = 75/245 (30%), Positives = 113/245 (46%), Gaps = 25/245 (10%)
Query: 46 DSPLLQAAKENDLRLLKILLLN-QSCDFQQRGA------VGETALHVAALY---DNLEAA 95
+ A +++ + L+ LL Q + + G+T L A L +
Sbjct: 14 RRSIFDAVAQSNCQELESLLPFLQRSKKRLTDSEFKDPETGKTCLLKAMLNLHNGQNDTI 73
Query: 96 TLLMEAAPELAKEPALCEP------FVGQTALHIAVMNQNLNLVRALLARGASVSARATG 149
LL++ A + + GQTALHIA+ +N+ LV L+ GA V A A G
Sbjct: 74 ALLLDVARKTDSLKQFVNASYTDSYYKGQTALHIAIERRNMTLVTLLVENGADVQAAANG 133
Query: 150 AAFRRSPHNL-IYYGEHPLSFAACVGSEEIVRLLIEH---GADIRAQDSLGNTVLHILIL 205
F+++ Y+GE PLS AAC IV+ L+++ ADI A+DS+GNTVLH L+
Sbjct: 134 DFFKKTKGRPGFYFGELPLSLAACTNQLAIVKFLLQNSWQPADISARDSVGNTVLHALVE 193
Query: 206 QPNKT-----FACQMYNLLLSYDEHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLM 260
+ T F MYN +L LE + N +GLTP LA G + +++
Sbjct: 194 VADNTVDNTKFVTSMYNEILILGAKLHPTLKLEEITNRKGLTPLALAASSGKIGVLAYIL 253
Query: 261 QKRKH 265
Q+ H
Sbjct: 254 QREIH 258
>5AQB-A nrPDB
Length = 428
Score = 187 bits (475), Expect = 1e-47, Method: Composition-based stats.
Identities = 52/169 (30%), Positives = 75/169 (44%), Gaps = 20/169 (11%)
Query: 47 SPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELA 106
LL+AA+ +IL+ N D VG T LH+AA +LE L++ ++
Sbjct: 16 KKLLEAARAGQDDECRILMAN-GADVNALDEVGWTPLHLAAW-GHLEIVECLLKNGADVN 73
Query: 107 KEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHP 166
G T LH+A + +L +V LL GA V+A G P
Sbjct: 74 -----AADIDGYTPLHLAAFSGHLEIVEVLLKYGADVNADDQA-------------GFTP 115
Query: 167 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQM 215
L AA G EIV +L+++GAD+ AQD G T + I N+ A +
Sbjct: 116 LHLAAIFGHLEIVEVLLKNGADVNAQDKFGKTPRDLAIDNGNEDIAEVL 164
Score = 128 bits (321), Expect = 9e-30, Method: Composition-based stats.
Identities = 45/193 (23%), Positives = 69/193 (35%), Gaps = 33/193 (17%)
Query: 121 LHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVR 180
L A + R L+A GA V+A G PL AA G EIV
Sbjct: 18 LLEAARAGQDDECRILMANGADVNALDE-------------VGWTPLHLAA-WGHLEIVE 63
Query: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQG 240
L+++GAD+ A D G T LH+ + ++ +LL Y + G
Sbjct: 64 CLLKNGADVNAADIDGYTPLHLAAFSGH----LEIVEVLLKYGADVNADDQ-------AG 112
Query: 241 LTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSWGEELSFLELVVS-- 298
TP LA + G+ + + L++ V T DL + + L +
Sbjct: 113 FTPLHLAAIFGHLEIVEVLLKNGADVN-AQDKFGKTPRDLAIDNGNEDIAEVLGKAATLV 171
Query: 299 -----SKKREARQ 306
+ + AR
Sbjct: 172 KVKDAADQLGARV 184
Score = 87.5 bits (215), Expect = 2e-17, Method: Composition-based stats.
Identities = 24/104 (23%), Positives = 45/104 (43%), Gaps = 6/104 (5%)
Query: 47 SPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELA 106
+PL AA L ++++LL D G T LH+AA++ +LE +L++ ++
Sbjct: 81 TPLHLAAFSGHLEIVEVLLKY-GADVNADDQAGFTPLHLAAIFGHLEIVEVLLKNGADVN 139
Query: 107 KEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGA 150
+ G+T +A+ N N ++ L V +
Sbjct: 140 AQDKF-----GKTPRDLAIDNGNEDIAEVLGKAATLVKVKDAAD 178
>5AQ7-A nrPDB
Length = 418
Score = 186 bits (473), Expect = 2e-47, Method: Composition-based stats.
Identities = 54/198 (27%), Positives = 83/198 (41%), Gaps = 24/198 (12%)
Query: 47 SPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELA 106
LL+AA+ ++ILL N D G T LH+AA +L +L++ ++
Sbjct: 16 KKLLEAARAGQDDEVRILLAN-GADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADVN 74
Query: 107 KEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHP 166
G T LH+A +L +V LL GA V+A G P
Sbjct: 75 -----ANDERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATDV-------------IGTAP 116
Query: 167 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSY---- 222
L AA G +EIV +L++ GAD+ AQD G L + Q + A ++ L
Sbjct: 117 LHLAAMWGYKEIVEVLLKAGADVDAQDKFGKRPLWLAADQGHAEIAAKLVAARLKARVGY 176
Query: 223 -DEHSDHLQSLELVPNHQ 239
+ + + LE V + +
Sbjct: 177 IELDLNSGKILESVRSEE 194
Score = 109 bits (273), Expect = 4e-24, Method: Composition-based stats.
Identities = 40/173 (23%), Positives = 61/173 (35%), Gaps = 25/173 (14%)
Query: 121 LHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVR 180
L A + VR LLA GA V+ G PL AA G IV
Sbjct: 18 LLEAARAGQDDEVRILLANGADVNTADET-------------GFTPLHLAAWEGHLGIVE 64
Query: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQG 240
+L+++GAD+ A D G+T LH+ + ++ +LL + + G
Sbjct: 65 VLLKNGADVNANDERGHTPLHLAAYTGH----LEIVEVLLKNGAGVNATDVI-------G 113
Query: 241 LTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSWGEELSFL 293
P LA + G + + L++ V L E + L
Sbjct: 114 TAPLHLAAMWGYKEIVEVLLKAGADVD-AQDKFGKRPLWLAADQGHAEIAAKL 165
Score = 47.8 bits (112), Expect = 2e-05, Method: Composition-based stats.
Identities = 27/155 (17%), Positives = 46/155 (29%), Gaps = 49/155 (31%)
Query: 167 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHS 226
L AA G ++ VR+L+ +GAD+ D
Sbjct: 18 LLEAARAGQDDEVRILLANGADVNTAD--------------------------------- 44
Query: 227 DHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSW 286
G TP LA EG+ + + L++ V T L
Sbjct: 45 -----------ETGFTPLHLAAWEGHLGIVEVLLKNGADVN-ANDERGHTPLHLAAYTGH 92
Query: 287 GEELSFLELVVSSKKREARQILEQTPVKELVSFKW 321
E + L + + A ++ P+ ++ W
Sbjct: 93 LEIVEVL--LKNGAGVNATDVIGTAPLH--LAAMW 123
>4OAU-C nrPDB
Length = 699
Score = 184 bits (467), Expect = 1e-46, Method: Composition-based stats.
Identities = 56/233 (24%), Positives = 104/233 (44%), Gaps = 19/233 (8%)
Query: 36 VNMLQQERIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAA 95
VN ++E +PL A + + ++ LLL D R G T +AA+ +++
Sbjct: 31 VNFQEEEGGW-TPLHNAVQMSREDIV-ELLLRHGADPVLRKKNGATPFILAAIAGSVKLL 88
Query: 96 TLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRS 155
L + ++ + F G TA A + + ++ L RGA+V+ R +
Sbjct: 89 KLFLSKGADVNEC-----DFYGFTAFMEAAVYGKVKALKFLYKRGANVNLRRKT---KED 140
Query: 156 PHNLIYYGEHPLSFAACVGSEEIVRLLI-EHGADIRAQDSLGNTVLHILILQPNKTFACQ 214
L G L AA G E++++L+ E GAD+ A D++G L +L + +
Sbjct: 141 QERLRKGGATALMDAAEKGHVEVLKILLDEMGADVNACDNMGRNALIHALLSSDDSDVEA 200
Query: 215 MYNLLLSYDEHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQ 267
+ +LLL + + V +G TP LA + + + Q L++ ++H++
Sbjct: 201 ITHLLLDHGADVN-------VRGERGKTPLILAVEKKHLGLVQRLLE-QEHIE 245
Score = 69.4 bits (168), Expect = 5e-12, Method: Composition-based stats.
Identities = 33/139 (23%), Positives = 53/139 (38%), Gaps = 24/139 (17%)
Query: 50 LQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKEP 109
L ++ ++D+ + LLL+ D RG G+T L +A +L L+E
Sbjct: 190 LLSSDDSDVEAITHLLLDHGADVNVRGERGKTPLILAVEKKHLGLVQRLLEQ----EHIE 245
Query: 110 ALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSF 169
G+TAL +AV + + L RGAS L
Sbjct: 246 INDTDSDGKTALLLAVELKLKKIAELLCKRGASTDCGD-------------------LVM 286
Query: 170 AACVGSEE-IVRLLIEHGA 187
A + +V++L+ HGA
Sbjct: 287 TARRNYDHSLVKVLLSHGA 305
Score = 57.4 bits (137), Expect = 2e-08, Method: Composition-based stats.
Identities = 29/150 (19%), Positives = 56/150 (37%), Gaps = 13/150 (8%)
Query: 167 LSFAACVGSEEIVRLLIEHGADIRAQDSLGN-TVLHILILQPNKTFACQMYNLLLSYDEH 225
L A ++V+ L+E GA++ Q+ G T LH + + LLL +
Sbjct: 9 LIKAVQNEDVDLVQQLLEGGANVNFQEEEGGWTPLHNAVQMSREDIV----ELLLRHGAD 64
Query: 226 SDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDS 285
++ G TPF LA + G+ + + + K V T + +
Sbjct: 65 -------PVLRKKNGATPFILAAIAGSVKLLKLFLSKGADVNEC-DFYGFTAFMEAAVYG 116
Query: 286 WGEELSFLELVVSSKKREARQILEQTPVKE 315
+ L FL ++ + +Q +++
Sbjct: 117 KVKALKFLYKRGANVNLRRKTKEDQERLRK 146
Score = 46.6 bits (109), Expect = 4e-05, Method: Composition-based stats.
Identities = 23/96 (23%), Positives = 41/96 (42%), Gaps = 10/96 (10%)
Query: 46 DSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPEL 105
+PL+ A ++ L L++ LL + + + G+TAL +A + A LL +
Sbjct: 220 KTPLILAVEKKHLGLVQRLLEQEHIEINDTDSDGKTALLLAVELKLKKIAELLCKRGAST 279
Query: 106 AKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGA 141
+ A N + +LV+ LL+ GA
Sbjct: 280 DCGDL----------VMTARRNYDHSLVKVLLSHGA 305
>6FES-A nrPDB
Length = 367
Score = 179 bits (455), Expect = 3e-45, Method: Composition-based stats.
Identities = 51/166 (30%), Positives = 73/166 (43%), Gaps = 19/166 (11%)
Query: 47 SPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELA 106
LL+AA+ ++ILL N D G T LH+AA +L +L++ ++
Sbjct: 8 KKLLEAARAGQDDEVRILLAN-GADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADVN 66
Query: 107 KEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHP 166
G T LH+A +L +V LL GA V+A G P
Sbjct: 67 -----ANDERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATDV-------------IGTAP 108
Query: 167 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFA 212
L AA G EEIV +L+++GAD RAQD G T + ++ A
Sbjct: 109 LHLAAMWGHEEIVEVLLKNGADARAQDKFGKTPEDLARDNGYESVA 154
Score = 114 bits (285), Expect = 1e-25, Method: Composition-based stats.
Identities = 39/165 (23%), Positives = 62/165 (37%), Gaps = 25/165 (15%)
Query: 121 LHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVR 180
L A + VR LLA GA V+ G PL AA G IV
Sbjct: 10 LLEAARAGQDDEVRILLANGADVNTADET-------------GFTPLHLAAWEGHLGIVE 56
Query: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQG 240
+L+++GAD+ A D G+T LH+ + ++ +LL + + G
Sbjct: 57 VLLKNGADVNANDERGHTPLHLAAYTGH----LEIVEVLLKNGAGVNATDVI-------G 105
Query: 241 LTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDS 285
P LA + G+ + + L++ + T DL +
Sbjct: 106 TAPLHLAAMWGHEEIVEVLLKNGADAR-AQDKFGKTPEDLARDNG 149
Score = 37.4 bits (85), Expect = 0.021, Method: Composition-based stats.
Identities = 13/51 (25%), Positives = 22/51 (43%), Gaps = 1/51 (1%)
Query: 47 SPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATL 97
+PL AA ++++LL N D + + G+T +A A L
Sbjct: 107 APLHLAAMWGHEEIVEVLLKN-GADARAQDKFGKTPEDLARDNGYESVARL 156
>6G1K-A nrPDB
Length = 921
Score = 175 bits (444), Expect = 6e-44, Method: Composition-based stats.
Identities = 102/663 (15%), Positives = 221/663 (33%), Gaps = 116/663 (17%)
Query: 23 PVGEQDWEQYRDRVNML-----QQERIRDSPLLQAAKENDLRLLKILLL----NQSCDFQ 73
D YRDR+ + + ++ L A ++ D +K+ L +
Sbjct: 5 YFRRTDNSSYRDRIPLRIVRAESELSTQEKSYLSAVEKGDYASVKLALEEAEIYFKININ 64
Query: 74 QRGAVGETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLV 133
+G TAL +A +NLE LL+ +VG LH A+ + + V
Sbjct: 65 CIDPLGRTALLIAIENENLEIIELLLS-----------FNVYVGDALLH-AIRKEVVGAV 112
Query: 134 RALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQD 193
LL + + P+ AA + EI+++L++ G +
Sbjct: 113 ELLLNHKKPSGEKQVPPILLDKQFSDFTPDITPIILAAHTNNYEIIKMLVQKGVSVPQPH 172
Query: 194 SLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQG-LTPFKLAGVEGN 252
+ + + + + L Y + SL + + LT F+L+
Sbjct: 173 EVRCNCVE-CVSSSDVDSLRHSRSRLNIYKALASP--SLIALSSEDPFLTAFQLSWELQE 229
Query: 253 TVMFQHLMQKR-KHVQWTCGPLTSTLYD-------LTEIDSWGEELSFLELVVSSK---- 300
++ + + + C L D L I ++ ++++ L+ +++
Sbjct: 230 LSKVENEFKAEYEELSHQCKHFAKDLLDQTRSSRELELILNFRDDMNLLQDEANNELARL 289
Query: 301 ----KREARQILEQTPVKELVSFKWKK------------------YGRPYFCVLASLYIL 338
K ++ + Q ++L++ +W + F +L+ Y++
Sbjct: 290 KLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAGKLITCVFIGLMFPLLSLCYLV 349
Query: 339 Y---------------MICFTTCCIYRPLKLRDDNRTDPRDITILQQKLLQEAYVTHQDN 383
IC T Y + ++ + V
Sbjct: 350 APKSRYGLFIRKPFIKFICHT--ASYLTFLFLLLLASQHIVSNNPDRQGPKPTTV----- 402
Query: 384 IRLVGELVTVTGAVIILLLEIPDIFRVGASRYF--GQTILGGPFHVIIITYASLVLLTMV 441
E + + + + EI ++ G Y ++ + + + SL ++ V
Sbjct: 403 -----EWMILPWVLGFIWTEIKQMWDGGFQDYIHDWWNLMDFVMNSLYLATISLKIVAYV 457
Query: 442 MR-----LTNMNGEVVPLSFALVLGWCSVMYFAR------GFQMLGPFTIMIQKMIFGDL 490
L V ++ R LGP I + +M+ D+
Sbjct: 458 KYSGCKPRDTWEMWHPTLVAEAVFAIANIFSSLRLISLFTANSHLGPLQISLGRMLL-DI 516
Query: 491 MRFCWLMAVVILGFASAFH-ITFQTEDPNNLG-------EFSDYPTALFSTFELFLTIID 542
++F ++ +V+L FA+ + + F E+ + ++ + LF T + I
Sbjct: 517 LKFLFIYCLVLLAFANGLNQLYFYYENSEGMTCKGIRCERQNNAFSTLFETLQSLFWSIF 576
Query: 543 GPANYSVD--------LPFMYCITYAAFAIIATLLMLNLFIAMMGDTHWRVAQERDELWR 594
G + V F+ + + +I+ +++LN+ IAMM +++ +A D W+
Sbjct: 577 GLISLYVTNVKADHKFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQHIADHADIEWK 636
Query: 595 AQV 597
Sbjct: 637 FAR 639
>3B7B-A nrPDB
Length = 237
Score = 173 bits (439), Expect = 2e-43, Method: Composition-based stats.
Identities = 51/251 (20%), Positives = 92/251 (36%), Gaps = 32/251 (12%)
Query: 36 VNMLQQERIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAA 95
+N + + + SPL AA+ + + +L+ + T L AA ++LEA
Sbjct: 2 MNFKMEHQNKRSPLHAAAEAGHVDICHMLVQA-GANIDTCSEDQRTPLMEAAENNHLEAV 60
Query: 96 TLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGA-SVSARATGAAFRR 154
L++A + + G T LH+A + +V+ LL+ G V+ + G
Sbjct: 61 KYLIKAGALVD-----PKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDG----- 110
Query: 155 SPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQ 214
G P+ +A ++V+LL+ G+DI +D+ N LH A
Sbjct: 111 --------GWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIA-- 160
Query: 215 MYNLLLSYDEHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLT 274
+LL+ + N G +P +A E + + V
Sbjct: 161 --EILLAAKCDLHAV-------NIHGDSPLHIAARENRYDCVVLFLSRDSDVTLK-NKEG 210
Query: 275 STLYDLTEIDS 285
T ++S
Sbjct: 211 ETPLQCASLNS 221
>6BY9-A nrPDB
Length = 328
Score = 172 bits (436), Expect = 5e-43, Method: Composition-based stats.
Identities = 51/250 (20%), Positives = 91/250 (36%), Gaps = 32/250 (12%)
Query: 37 NMLQQERIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAAT 96
N + + + SPL AA+ + + +L+ + T L AA ++LEA
Sbjct: 94 NFKMEHQNKRSPLHAAAEAGHVDICHMLVQA-GANIDTCSEDQRTPLMEAAENNHLEAVK 152
Query: 97 LLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGA-SVSARATGAAFRRS 155
L++A + + G T LH+A + +V+ LL+ G V+ + G
Sbjct: 153 YLIKAGALVD-----PKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDG------ 201
Query: 156 PHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQM 215
G P+ +A ++V+LL+ G+DI +D+ N LH A
Sbjct: 202 -------GWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIA--- 251
Query: 216 YNLLLSYDEHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTS 275
+LL+ + N G +P +A E + + V
Sbjct: 252 -EILLAAKCDLHAV-------NIHGDSPLHIAARENRYDCVVLFLSRDSDVTLK-NKEGE 302
Query: 276 TLYDLTEIDS 285
T ++S
Sbjct: 303 TPLQCASLNS 312
Score = 67.8 bits (164), Expect = 2e-11, Method: Composition-based stats.
Identities = 27/157 (17%), Positives = 48/157 (30%), Gaps = 22/157 (14%)
Query: 121 LHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVR 180
L+ + L V +L G + + PL AA G +I
Sbjct: 71 LYFSARQGELQKVLLMLVDGIDPN------FKMEHQNK-----RSPLHAAAEAGHVDICH 119
Query: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQG 240
+L++ GA+I T L + + L+ D + +G
Sbjct: 120 MLVQAGANIDTCSEDQRTPLMEAAENNH----LEAVKYLIKAGALVDPKDA-------EG 168
Query: 241 LTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTL 277
T LA +G+ + Q+L+ + T
Sbjct: 169 STCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTP 205
Score = 30.5 bits (67), Expect = 3.0, Method: Composition-based stats.
Identities = 11/71 (15%), Positives = 26/71 (36%), Gaps = 3/71 (4%)
Query: 214 QMYNLLLSYDEHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPL 273
++ +LL + D +E + +P A G+ + L+Q ++
Sbjct: 79 ELQKVLLMLVDGIDPNFKME---HQNKRSPLHAAAEAGHVDICHMLVQAGANIDTCSEDQ 135
Query: 274 TSTLYDLTEID 284
+ L + E +
Sbjct: 136 RTPLMEAAENN 146
>6AUN-A nrPDB
Length = 752
Score = 167 bits (422), Expect = 2e-41, Method: Composition-based stats.
Identities = 63/246 (25%), Positives = 98/246 (39%), Gaps = 47/246 (19%)
Query: 47 SPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAP--- 103
+PL A ++ D +L L+ GETA H A DN + LL + A
Sbjct: 154 TPLHLACRKGDSEILVELVQYCHAQMDVTDNKGETAFHYAVQGDNSQVLQLLGKNASAGL 213
Query: 104 -ELAKEPALCEPFVGQTALHIAVMNQNLNLVRALL-------ARGASVSARATGAAF-RR 154
++ K+ G T LH+A +VR LL G S T F ++
Sbjct: 214 NQVNKQ--------GLTPLHLACQMGKQEMVRVLLLCNARCNVMGPSGFPIHTAMKFSQK 265
Query: 155 SPHNLIY-------------YGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLH 201
+I YG PL +A + E+ R+L++ G D+ + + GNT LH
Sbjct: 266 GCAEMIISMDSSQIHSKDPRYGASPLHWA---KNAEMARMLLKRGCDVDSTSAAGNTALH 322
Query: 202 ILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQ 261
+ +++ F C M +LL+Y ++ P G TP LA + N M + L+
Sbjct: 323 VAVMR--NRFDCVM--VLLTYGANAG-------TPGEHGNTPLHLAISKDNMEMIKALIV 371
Query: 262 KRKHVQ 267
V
Sbjct: 372 FGAEVD 377
Score = 80.9 bits (198), Expect = 2e-15, Method: Composition-based stats.
Identities = 50/246 (20%), Positives = 89/246 (36%), Gaps = 29/246 (11%)
Query: 48 PLLQAAKENDLRLLKILLLNQSCDFQQRGAV-GETALHVAALYDNLEAATLLMEAAPELA 106
P+ A K + ++++ S + G + LH A N E A +L++ ++
Sbjct: 255 PIHTAMKFSQKGCAEMIISMDSSQIHSKDPRYGASPLHWA---KNAEMARMLLKRGCDVD 311
Query: 107 KEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHP 166
A G TALH+AVM + V LL GA+ +G P
Sbjct: 312 STSAA-----GNTALHVAVMRNRFDCVMVLLTYGAN-------------AGTPGEHGNTP 353
Query: 167 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHS 226
L A + E+++ LI GA++ + G T + + Q+ +L+
Sbjct: 354 LHLAISKDNMEMIKALIVFGAEVDTPNDFGETPAFMA-----SKISKQLQDLMPISRAR- 407
Query: 227 DHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSW 286
L + + + + L G ++Q ++ G T L+D S
Sbjct: 408 KPAFILSSMRDEKRIHDHLLCLDGGGVKGL-VIIQLLIAIEKASGVATKDLFDWVAGTST 466
Query: 287 GEELSF 292
G L+
Sbjct: 467 GGILAL 472
Score = 36.2 bits (82), Expect = 0.046, Method: Composition-based stats.
Identities = 26/149 (17%), Positives = 47/149 (31%), Gaps = 15/149 (10%)
Query: 199 VLHILILQPNKTFACQ-----MYNLLLSYDEHSDHLQS-----LELVPNHQGLTPFKLAG 248
VLH+ +LQ + +L + S N +G TP LA
Sbjct: 101 VLHVEVLQHLSDLIRSHPSWTVTHLAVELGIRECFHHSRIISCANSTENEEGCTPLHLAC 160
Query: 249 VEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSWGEELSFLELVVSSKKREARQIL 308
+G++ + L+Q T + G+ L+L+ + Q+
Sbjct: 161 RKGDSEILVELVQYCHAQMDVTDNKGETAFHYA---VQGDNSQVLQLLGKNASAGLNQVN 217
Query: 309 EQ--TPVKELVSFKWKKYGRPYFCVLASL 335
+Q TP+ ++ R A
Sbjct: 218 KQGLTPLHLACQMGKQEMVRVLLLCNARC 246
>5Z96-A nrPDB
Length = 755
Score = 162 bits (410), Expect = 5e-40, Method: Composition-based stats.
Identities = 103/667 (15%), Positives = 218/667 (32%), Gaps = 116/667 (17%)
Query: 19 LISWPVGEQDWEQYRDRVNML-----QQERIRDSPLLQAAKENDLRLLKILLL----NQS 69
+ + YRDR+ + + + L A ++ D +K L
Sbjct: 1 MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFK 60
Query: 70 CDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQN 129
+ +G TAL +A EL + +VG LH A+ +
Sbjct: 61 ININCIDPLGRTALLIAIEN-----------ENLELIELLLSFNVYVGDALLH-AIRKEV 108
Query: 130 LNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADI 189
+ V LL + + P+ AA + EI++LL++ G +
Sbjct: 109 VGAVELLLNHKKPSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSV 168
Query: 190 RAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQG-LTPFKLAG 248
+ + + + + L Y + SL + + LT F+L+
Sbjct: 169 PRPHEVRCNCVE-CVSSSDVDSLRHSRSRLNIYKALASP--SLIALSSEDPFLTAFQLSW 225
Query: 249 VEGNTVMFQHLMQKR-KHVQWTCGPLTSTLYD-------LTEIDSWGEELSFLELVVSSK 300
++ + + + C L D L I ++ ++ S +E +
Sbjct: 226 ELQELSKVENEFKSEYEELSRQCKQFAKDLLDQTRSSRELEIILNYRDDNSLIEEQSGND 285
Query: 301 --------KREARQILEQTPVKELVSFKW-KKYGRPY-----------------FCVLAS 334
K ++ + Q ++L++ +W ++ F V +
Sbjct: 286 LARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSV 345
Query: 335 LYILY---------------MICFTTCCIYRPLKLRDDNRTDPRDITILQQKLLQEAYVT 379
Y++ IC T Y + D + L ++ V
Sbjct: 346 CYLIAPKSPLGLFIRKPFIKFICHT--ASYLTFLFLLLLASQHIDRSDLNRQGPPPTIV- 402
Query: 380 HQDNIRLVGELVTVTGAVIILLLEIPDIFRVGASRYF--GQTILGGPFHVIIITYASLVL 437
E + + + + EI ++ G Y ++ + + + SL +
Sbjct: 403 ---------EWMILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKI 453
Query: 438 LTMVMRLT-----NMNGEVVPLSFALVLGWCSVMYFAR------GFQMLGPFTIMIQKMI 486
+ V + + L + ++ R LGP I + +M+
Sbjct: 454 VAFVKYSALNPRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRML 513
Query: 487 FGDLMRFCWLMAVVILGFASAFH-ITFQTEDPNNLG-------EFSDYPTALFSTFELFL 538
D+++F ++ +V+L FA+ + + F E+ L + ++ + LF T +
Sbjct: 514 L-DILKFLFIYCLVLLAFANGLNQLYFYYEETKGLSCKGIRCEKQNNAFSTLFETLQSLF 572
Query: 539 TIIDGPANYSVD--------LPFMYCITYAAFAIIATLLMLNLFIAMMGDTHWRVAQERD 590
I G N V F+ + + +I+ +++LN+ IAMM +++ +A D
Sbjct: 573 WSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHAD 632
Query: 591 ELWRAQV 597
W+
Sbjct: 633 IEWKFAR 639
>4Z68-A nrPDB
Length = 155
Score = 161 bits (408), Expect = 9e-40, Method: Composition-based stats.
Identities = 46/174 (26%), Positives = 71/174 (40%), Gaps = 23/174 (13%)
Query: 46 DSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPEL 105
D LL+AAK D+ +K L QS + + T LH AA Y+ + L++ ++
Sbjct: 4 DRQLLEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADV 63
Query: 106 AKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEH 165
+ G LH A + + L+ GA V+
Sbjct: 64 -----HAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKF-------------T 105
Query: 166 PLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLL 219
PL AA G EI +LL++HGAD ++ GNT L ++ K + +LL
Sbjct: 106 PLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLV-----KDGDTDIQDLL 154
Score = 80.1 bits (196), Expect = 3e-15, Method: Composition-based stats.
Identities = 37/173 (21%), Positives = 58/173 (33%), Gaps = 25/173 (14%)
Query: 121 LHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVR 180
L A ++ V+ L SV+ R PL FAA +V
Sbjct: 7 LLEAAKAGDVETVKKLCTV-QSVNCRDIEGRQS-----------TPLHFAAGYNRVSVVE 54
Query: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQG 240
L++HGAD+ A+D G LH + A LL+ + + +
Sbjct: 55 YLLQHGADVHAKDKGGLVPLHNACSYGHYEVA----ELLVKHGAVVNVADLWK------- 103
Query: 241 LTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSWGEELSFL 293
TP A +G + + L+Q +T DL + D + L
Sbjct: 104 FTPLHEAAAKGKYEICKLLLQHGADPT-KKNRDGNTPLDLVK-DGDTDIQDLL 154
>5GP7-A nrPDB
Length = 169
Score = 158 bits (399), Expect = 9e-39, Method: Composition-based stats.
Identities = 42/158 (26%), Positives = 68/158 (43%), Gaps = 18/158 (11%)
Query: 46 DSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPEL 105
D+ LL AAK+ L ++ L ++ + + T LH+AA Y+NLE A L+E ++
Sbjct: 10 DAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADV 69
Query: 106 AKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEH 165
+ G LH A ++++ L+ V+A A
Sbjct: 70 NAQDK-----GGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAF-------------T 111
Query: 166 PLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHIL 203
PL AA G ++ LL+ HGAD ++ G T L +
Sbjct: 112 PLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLA 149
Score = 85.2 bits (209), Expect = 8e-17, Method: Composition-based stats.
Identities = 40/173 (23%), Positives = 56/173 (32%), Gaps = 24/173 (13%)
Query: 112 CEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAA 171
+ G AL A L V+ L +++ R T PL AA
Sbjct: 4 SDLLRGDAALLDAAKKGCLARVQKLCTP-ENINCRDTQGRNS-----------TPLHLAA 51
Query: 172 CVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQS 231
+ E+ L+EHGAD+ AQD G LH + A LL+ Y+ +
Sbjct: 52 GYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAA----LLIKYNTCVNATDK 107
Query: 232 LELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEID 284
TP A +G T + L+ T DL D
Sbjct: 108 W-------AFTPLHEAAQKGRTQLCALLLAHGADPT-MKNQEGQTPLDLATAD 152
Score = 75.9 bits (185), Expect = 6e-14, Method: Composition-based stats.
Identities = 33/125 (26%), Positives = 45/125 (36%), Gaps = 19/125 (15%)
Query: 47 SPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELA 106
+PL AA N+L + + LL D + G LH AA Y +++ A LL++ +
Sbjct: 45 TPLHLAAGYNNLEVAEYLLE-HGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVN 103
Query: 107 KEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHP 166
T LH A L LLA GA P G+ P
Sbjct: 104 -----ATDKWAFTPLHEAAQKGRTQLCALLLAHGAD-------------PTMKNQEGQTP 145
Query: 167 LSFAA 171
L A
Sbjct: 146 LDLAT 150
Score = 39.7 bits (91), Expect = 0.004, Method: Composition-based stats.
Identities = 13/44 (29%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 47 SPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYD 90
+PL +AA++ +L +LL D + G+T L +A D
Sbjct: 111 TPLHEAAQKGRTQLCALLLA-HGADPTMKNQEGQTPLDLATADD 153
>4O1O-A nrPDB
Length = 717
Score = 150 bits (379), Expect = 2e-36, Method: Composition-based stats.
Identities = 60/248 (24%), Positives = 95/248 (38%), Gaps = 24/248 (9%)
Query: 24 VGEQDWEQYRD------RVNMLQQERIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGA 77
V E D EQ R N ++E SPL A + D L LLL D R
Sbjct: 16 VQEADIEQVRQLLERGADANFQEEEWGW-SPLHSAVQM-DSEDLVALLLKHGADPCLRKR 73
Query: 78 VGETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALL 137
G T +A + N+ LL+ ++ + G TA A + + +R L
Sbjct: 74 NGATPFIIAGITGNVRLLQLLLPNVEDVNECDVN-----GFTAFMEAAVYGRVEALRFLY 128
Query: 138 ARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLI-EHGADIRAQDSLG 196
GA V+ ++ + G L AA G +V +L+ A++ A+D++G
Sbjct: 129 ENGADVNMHRKT---KQDQERIRKGGATALMDAAEKGHVGVVTILLHAMKAEVDARDNMG 185
Query: 197 NTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMF 256
L +L P+ A + LLL + + V TP LA N +
Sbjct: 186 RNALVYALLNPDDGKAKAITRLLLDHGADVN-------VRGEGSKTPLILAVERKNLDLV 238
Query: 257 QHLMQKRK 264
Q L+++ +
Sbjct: 239 QMLLEQEQ 246
Score = 72.8 bits (177), Expect = 5e-13, Method: Composition-based stats.
Identities = 45/218 (20%), Positives = 70/218 (32%), Gaps = 65/218 (29%)
Query: 40 QQERIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLM 99
++R +P + A ++RLL++LL N D + G TA AA+Y +EA L
Sbjct: 70 LRKRNGATPFIIAGITGNVRLLQLLLPNVE-DVNECDVNGFTAFMEAAVYGRVEALRFLY 128
Query: 100 EAAPELAKEPALCEPFV-----GQTALHIAVMNQNLNLV--------------------- 133
E ++ + G TAL A ++ +V
Sbjct: 129 ENGADVNMHRKTKQDQERIRKGGATALMDAAEKGHVGVVTILLHAMKAEVDARDNMGRNA 188
Query: 134 -----------------RALLARGASVSARATGAAF---------------------RRS 155
R LL GA V+ R G+ +
Sbjct: 189 LVYALLNPDDGKAKAITRLLLDHGADVNVRGEGSKTPLILAVERKNLDLVQMLLEQEQIE 248
Query: 156 PHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQD 193
++ G+ L A + EEI +LL GA D
Sbjct: 249 VNDTDREGKTALLLAVELRLEEIAKLLCHRGASTNCGD 286
Score = 55.9 bits (133), Expect = 7e-08, Method: Composition-based stats.
Identities = 34/150 (22%), Positives = 56/150 (37%), Gaps = 13/150 (8%)
Query: 167 LSFAACVGSEEIVRLLIEHGADIRAQDSL-GNTVLHILILQPNKTFACQMYNLLLSYDEH 225
L+ A E VR L+E GAD Q+ G + LH + ++ LLL +
Sbjct: 12 LTQAVQEADIEQVRQLLERGADANFQEEEWGWSPLHSAVQMDSEDLVA----LLLKHGAD 67
Query: 226 SDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDS 285
+ G TPF +AG+ GN + Q L+ + V T + +
Sbjct: 68 PC-------LRKRNGATPFIIAGITGNVRLLQLLLPNVEDVNEC-DVNGFTAFMEAAVYG 119
Query: 286 WGEELSFLELVVSSKKREARQILEQTPVKE 315
E L FL + + +Q +++
Sbjct: 120 RVEALRFLYENGADVNMHRKTKQDQERIRK 149
Score = 43.9 bits (102), Expect = 3e-04, Method: Composition-based stats.
Identities = 25/130 (19%), Positives = 44/130 (33%), Gaps = 17/130 (13%)
Query: 46 DSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPEL 105
+PL+ A + +L L+++LL + + G+TAL +A E A LL
Sbjct: 223 KTPLILAVERKNLDLVQMLLEQEQIEVNDTDREGKTALLLAVELRLEEIAKLLCHRGAST 282
Query: 106 AKEPALCEPFVGQTALHIAVMNQNL--NLVRALLARGASVSARATGAAFRRSPHNLIYYG 163
+A+ +N +LV+ L A R ++ +G
Sbjct: 283 NCGDL------------VAIARRNYDSDLVKFLRLHKAGEDFRPPAENWKPQSSR---WG 327
Query: 164 EHPLSFAACV 173
E
Sbjct: 328 EALKHLHRIW 337
>5JHQ-A nrPDB
Length = 482
Score = 141 bits (355), Expect = 1e-33, Method: Composition-based stats.
Identities = 51/279 (18%), Positives = 91/279 (32%), Gaps = 31/279 (11%)
Query: 47 SPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELA 106
LL+A + D+ +K L+ + + + + LH AA + + L++ +
Sbjct: 17 RELLEACRNGDVSRVKRLVDAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANV- 75
Query: 107 KEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHP 166
G LH A + +V LL +GA +AR P
Sbjct: 76 ----HARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNY-------------TP 118
Query: 167 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHS 226
L AA G ++ +L++HGAD +++ G + L + + L S
Sbjct: 119 LHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAARS 178
Query: 227 DHLQSLELV----------PNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTST 276
+ + L + + + TP LA + Q L+Q V
Sbjct: 179 GNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVH-AKDKGGLV 237
Query: 277 LYDLTEIDSWGEELSFLELVVSSKKREARQILEQTPVKE 315
E L + A + + TP+ E
Sbjct: 238 PLHNACSYGHYEVTELL--LKHGACVNAMDLWQFTPLHE 274
Score = 140 bits (353), Expect = 2e-33, Method: Composition-based stats.
Identities = 50/286 (17%), Positives = 84/286 (29%), Gaps = 79/286 (27%)
Query: 45 RDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPE 104
+ LL+AA+ + L LL + + T LH+AA Y+ + LL++ +
Sbjct: 168 KKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGAD 227
Query: 105 LAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGE 164
+ + G LH A + + LL GA V+A
Sbjct: 228 V-----HAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQF------------- 269
Query: 165 HPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQP----------------- 207
PL AA E+ LL+ HGAD + G + + +
Sbjct: 270 TPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQA 329
Query: 208 ---------NKTFACQM---------------------------YNLLLSYDEHSDHLQS 231
KT A ++ LLL + +
Sbjct: 330 AREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVTELLLRKGANVNE--- 386
Query: 232 LELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTL 277
N +TP +A + + + L + + L T
Sbjct: 387 ----KNKDFMTPLHVAAERAHNDVMEVLHKHGAKMN-ALDTLGQTA 427
Score = 125 bits (313), Expect = 9e-29, Method: Composition-based stats.
Identities = 52/271 (19%), Positives = 83/271 (30%), Gaps = 58/271 (21%)
Query: 36 VNMLQQERIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAA 95
VN + SPL AA +++ LL + R G LH A + + E
Sbjct: 40 VNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQ-MGANVHARDDGGLIPLHNACSFGHAEVV 98
Query: 96 TLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAA---- 151
+LL+ + T LH A + +++ LL GA + R T
Sbjct: 99 SLLLCQGADPN-----ARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALD 153
Query: 152 -------------------------------------FRRSPHNLIYYGEHPLSFAACVG 174
+ H PL AA
Sbjct: 154 LADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYN 213
Query: 175 SEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLEL 234
IV+LL++HGAD+ A+D G LH + ++ LLL + + + +
Sbjct: 214 RVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGH----YEVTELLLKHGACVNAMDLWQ- 268
Query: 235 VPNHQGLTPFKLAGVEGNTVMFQHLMQKRKH 265
TP A + + L+
Sbjct: 269 ------FTPLHEAASKNRVEVCSLLLSHGAD 293
Score = 111 bits (277), Expect = 1e-24, Method: Composition-based stats.
Identities = 47/265 (17%), Positives = 83/265 (31%), Gaps = 61/265 (23%)
Query: 45 RDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPE 104
+ +PL AA N +R++++LL D + G LH A Y + E LL++
Sbjct: 202 KSTPLHLAAGYNRVRIVQLLLQ-HGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGAC 260
Query: 105 LAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGAS---VSARATGAAFRRSPHNLI- 160
+ T LH A + + LL+ GA V+ A L
Sbjct: 261 VN-----AMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRE 315
Query: 161 -----YYG--------------------------------EHPLSFAACVGSE---EIVR 180
+ G E L A ++
Sbjct: 316 RLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVTE 375
Query: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQG 240
LL+ GA++ ++ T LH+ + + + +L + + L +L G
Sbjct: 376 LLLRKGANVNEKNKDFMTPLHVAAERAHND----VMEVLHKHGAKMNALDTL-------G 424
Query: 241 LTPFKLAGVEGNTVMFQHLMQKRKH 265
T A + G+ + L+
Sbjct: 425 QTALHRAALAGHLQTCRLLLSYGSD 449
Score = 94.4 bits (233), Expect = 2e-19, Method: Composition-based stats.
Identities = 56/266 (21%), Positives = 82/266 (30%), Gaps = 82/266 (30%)
Query: 48 PLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPE--- 104
PL A + LLL T LH AA + +E +LL+ +
Sbjct: 238 PLHNACSYGHYE-VTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTL 296
Query: 105 LAKEPALCEP--------------FVGQ-------------------------------- 118
+ F G
Sbjct: 297 VNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHE 356
Query: 119 TALHIAVMNQN---LNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGS 175
TALH AV + + + LL +GA+V+ + PL AA
Sbjct: 357 TALHCAVASLHPKRKQVTELLLRKGANVNEKNKDF-------------MTPLHVAAERAH 403
Query: 176 EEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELV 235
+++ +L +HGA + A D+LG T LH L + Q LLLSY +
Sbjct: 404 NDVMEVLHKHGAKMNALDTLGQTALHRAALAGH----LQTCRLLLSYGSD-------PSI 452
Query: 236 PNHQGLTPFKLAGVEGNTVMFQHLMQ 261
+ QG T A GN Q ++
Sbjct: 453 ISLQGFT----AAQMGN-EAVQQILS 473
Score = 55.9 bits (133), Expect = 6e-08, Method: Composition-based stats.
Identities = 23/104 (22%), Positives = 42/104 (40%), Gaps = 10/104 (9%)
Query: 33 RDRVNMLQQERIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNL 92
R N+ ++ + +PL AA+ ++++L +G+TALH AAL +L
Sbjct: 379 RKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHK-HGAKMNALDTLGQTALHRAALAGHL 437
Query: 93 EAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRAL 136
+ LL+ + + G T A N + + L
Sbjct: 438 QTCRLLLSYGSDPSIIS-----LQGFT----AAQMGNEAVQQIL 472
Score = 29.3 bits (64), Expect = 5.8, Method: Composition-based stats.
Identities = 15/58 (25%), Positives = 22/58 (37%), Gaps = 5/58 (8%)
Query: 46 DSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAP 103
+ L +AA L+ ++LL D G T AA N +L E+ P
Sbjct: 425 QTALHRAALAGHLQTCRLLLSY-GSDPSIISLQGFT----AAQMGNEAVQQILSESTP 477
>5HKP-A nrPDB
Length = 351
Score = 139 bits (350), Expect = 4e-33, Method: Composition-based stats.
Identities = 51/286 (17%), Positives = 85/286 (29%), Gaps = 79/286 (27%)
Query: 45 RDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPE 104
+ LL+AA+ + L LL + + T LH+AA Y+ + LL++ +
Sbjct: 24 KKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGAD 83
Query: 105 LAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGE 164
+ + G LH A + + LL GA V+A
Sbjct: 84 V-----HAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQF------------- 125
Query: 165 HPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQP----------------- 207
PL AA E+ LL+ HGAD + G + + +
Sbjct: 126 TPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQA 185
Query: 208 ---------NKTFACQMYN---------------------------LLLSYDEHSDHLQS 231
KT A ++ N LLL + +
Sbjct: 186 AREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVAELLLRKGANVNE--- 242
Query: 232 LELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTL 277
N +TP +A + + + L + + L T
Sbjct: 243 ----KNKDFMTPLHVAAERAHNDVMEVLHKHGAKMN-ALDSLGQTA 283
Score = 110 bits (276), Expect = 1e-24, Method: Composition-based stats.
Identities = 47/265 (17%), Positives = 81/265 (30%), Gaps = 61/265 (23%)
Query: 45 RDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPE 104
+ +PL AA N +R++++LL D + G LH A Y + E LL++
Sbjct: 58 KSTPLHLAAGYNRVRIVQLLLQ-HGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGAC 116
Query: 105 LAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGAS---VSARATGAAFRRSPHNLI- 160
+ T LH A + + LL+ GA V+ A L
Sbjct: 117 VN-----AMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRE 171
Query: 161 -------------------------------------YYGEHPLSFAACVGSE---EIVR 180
E L A ++
Sbjct: 172 RLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVAE 231
Query: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQG 240
LL+ GA++ ++ T LH+ + + + +L + + L SL G
Sbjct: 232 LLLRKGANVNEKNKDFMTPLHVAAERAHND----VMEVLHKHGAKMNALDSL-------G 280
Query: 241 LTPFKLAGVEGNTVMFQHLMQKRKH 265
T A + G+ + L+
Sbjct: 281 QTALHRAALAGHLQTCRLLLSYGSD 305
Score = 95.2 bits (235), Expect = 1e-19, Method: Composition-based stats.
Identities = 57/266 (21%), Positives = 82/266 (30%), Gaps = 82/266 (30%)
Query: 48 PLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPE--- 104
PL A + LLL T LH AA + +E +LL+ +
Sbjct: 94 PLHNACSYGHYE-VTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTL 152
Query: 105 LAKEPALCEP--------------FVGQ-------------------------------- 118
+ F G
Sbjct: 153 VNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHE 212
Query: 119 TALHIAVMNQN---LNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGS 175
TALH AV + + + LL +GA+V+ + PL AA
Sbjct: 213 TALHCAVASLHPKRKQVAELLLRKGANVNEKNKDF-------------MTPLHVAAERAH 259
Query: 176 EEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELV 235
+++ +L +HGA + A DSLG T LH L + Q LLLSY +
Sbjct: 260 NDVMEVLHKHGAKMNALDSLGQTALHRAALAGH----LQTCRLLLSYGSD-------PSI 308
Query: 236 PNHQGLTPFKLAGVEGNTVMFQHLMQ 261
+ QG T A GN Q ++
Sbjct: 309 ISLQGFT----AAQMGN-EAVQQILS 329
Score = 56.3 bits (134), Expect = 4e-08, Method: Composition-based stats.
Identities = 23/104 (22%), Positives = 43/104 (41%), Gaps = 10/104 (9%)
Query: 33 RDRVNMLQQERIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNL 92
R N+ ++ + +PL AA+ ++++L ++G+TALH AAL +L
Sbjct: 235 RKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHK-HGAKMNALDSLGQTALHRAALAGHL 293
Query: 93 EAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRAL 136
+ LL+ + + G T A N + + L
Sbjct: 294 QTCRLLLSYGSDPSIIS-----LQGFT----AAQMGNEAVQQIL 328
Score = 33.2 bits (74), Expect = 0.38, Method: Composition-based stats.
Identities = 19/131 (14%), Positives = 33/131 (25%), Gaps = 13/131 (9%)
Query: 195 LGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELV----------PNHQGLTPF 244
G + L + + L S + + L + + + TP
Sbjct: 3 FGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPL 62
Query: 245 KLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSWGEELSFLELVVSSKKREA 304
LA + Q L+Q V E L + A
Sbjct: 63 HLAAGYNRVRIVQLLLQHGADVH-AKDKGGLVPLHNACSYGHYEVTELL--LKHGACVNA 119
Query: 305 RQILEQTPVKE 315
+ + TP+ E
Sbjct: 120 MDLWQFTPLHE 130
Score = 29.3 bits (64), Expect = 6.3, Method: Composition-based stats.
Identities = 15/58 (25%), Positives = 22/58 (37%), Gaps = 5/58 (8%)
Query: 46 DSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAP 103
+ L +AA L+ ++LL D G T AA N +L E+ P
Sbjct: 281 QTALHRAALAGHLQTCRLLLSY-GSDPSIISLQGFT----AAQMGNEAVQQILSESTP 333
>5CBO-A nrPDB
Length = 176
Score = 132 bits (331), Expect = 7e-31, Method: Composition-based stats.
Identities = 44/171 (25%), Positives = 67/171 (39%), Gaps = 32/171 (18%)
Query: 83 LHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGAS 142
L AA + +LM ++ G T LH+A + +V LL GA
Sbjct: 7 LLEAAHAGQDDEVRILMANGADVN-----AMDNFGVTPLHLAAYWGHFEIVEVLLKYGAD 61
Query: 143 VSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHI 202
V+A G+ PL AA G IV +L+++GAD+ AQD G T I
Sbjct: 62 VNASDAT-------------GDTPLHLAAKWGYLGIVEVLLKYGADVNAQDKFGKTAFDI 108
Query: 203 LILQPNKT--------------FACQMYNLLLSYDEHSDHLQSLELVPNHQ 239
I N+ F C ++ L+ + + +QSL+ P+
Sbjct: 109 SIDNGNEDLAEILCKNKAQQAAFYCILHMPNLNEAQRNGFIQSLKDDPSQS 159
Score = 95.6 bits (236), Expect = 7e-20, Method: Composition-based stats.
Identities = 36/138 (26%), Positives = 65/138 (47%), Gaps = 15/138 (10%)
Query: 167 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHS 226
L AA G ++ VR+L+ +GAD+ A D+ G T LH+ + ++ +LL Y
Sbjct: 7 LLEAAHAGQDDEVRILMANGADVNAMDNFGVTPLHLAAYWGH----FEIVEVLLKYGADV 62
Query: 227 DHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSW 286
+ + G TP LA G + + L++ V T +D++ ID+
Sbjct: 63 NASDA-------TGDTPLHLAAKWGYLGIVEVLLKYGADVN-AQDKFGKTAFDIS-IDNG 113
Query: 287 GEELSFLELVVSSKKREA 304
E+L+ E++ +K ++A
Sbjct: 114 NEDLA--EILCKNKAQQA 129
Score = 46.2 bits (108), Expect = 5e-05, Method: Composition-based stats.
Identities = 16/59 (27%), Positives = 29/59 (49%), Gaps = 1/59 (1%)
Query: 46 DSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPE 104
D+PL AAK L ++++LL D + G+TA ++ N + A +L + +
Sbjct: 70 DTPLHLAAKWGYLGIVEVLLKY-GADVNAQDKFGKTAFDISIDNGNEDLAEILCKNKAQ 127
>2DWZ-A nrPDB
Length = 231
Score = 116 bits (291), Expect = 3e-26, Method: Composition-based stats.
Identities = 52/214 (24%), Positives = 83/214 (38%), Gaps = 29/214 (13%)
Query: 53 AKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKEPALC 112
A L LK +L + TALH A + E L++ + +
Sbjct: 14 AYSGKLDELKERILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDA- 72
Query: 113 EPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAAC 172
G + LHIA +V+ALL +GA V+A G PL +AA
Sbjct: 73 ----GWSPLHIAASAGRDEIVKALLVKGAHVNAVNQN-------------GCTPLHYAAS 115
Query: 173 VGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSL 232
EI +L+E GA+ A+D T +H + N +M ++LL Y ++
Sbjct: 116 KNRHEIAVMLLEGGANPDAKDHYDATAMHRAAAKGN----LKMVHILLFYKASTN----- 166
Query: 233 ELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHV 266
+ + +G TP LA E + L+ + +
Sbjct: 167 --IQDTEGNTPLHLACDEERVEEAKFLVTQGASI 198
Score = 113 bits (282), Expect = 3e-25, Method: Composition-based stats.
Identities = 42/214 (19%), Positives = 74/214 (34%), Gaps = 32/214 (14%)
Query: 43 RIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAA 102
+ + L A +++ LL + G + LH+AA E L+
Sbjct: 38 QDSRTALHWACSAGHTEIVEFLLQL-GVPVNDKDDAGWSPLHIAASAGRDEIVKALLVKG 96
Query: 103 PELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYY 162
+ G T LH A + LL GA+ A+ +Y
Sbjct: 97 AHVNAVNQN-----GCTPLHYAASKNRHEIAVMLLEGGANPDAKD-------------HY 138
Query: 163 GEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSY 222
+ AA G+ ++V +L+ + A QD+ GNT LH+ + A L++
Sbjct: 139 DATAMHRAAAKGNLKMVHILLFYKASTNIQDTEGNTPLHLACDEERVEEA----KFLVTQ 194
Query: 223 DEHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMF 256
+ N + TP ++A +G +
Sbjct: 195 GASIY-------IENKEEKTPLQVA--KGGLGLI 219
Score = 95.2 bits (235), Expect = 9e-20, Method: Composition-based stats.
Identities = 50/209 (23%), Positives = 75/209 (35%), Gaps = 27/209 (12%)
Query: 106 AKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEH 165
K A +TALH A + +V LL G V+ + G
Sbjct: 29 DKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDA-------------GWS 75
Query: 166 PLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEH 225
PL AA G +EIV+ L+ GA + A + G T LH + A +LL +
Sbjct: 76 PLHIAASAGRDEIVKALLVKGAHVNAVNQNGCTPLHYAASKNRHEIAV----MLLEGGAN 131
Query: 226 SDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDS 285
D + T A +GN M L+ + +T L +
Sbjct: 132 PDAKDHYDA-------TAMHRAAAKGNLKMVHILLFYKASTN-IQDTEGNTPLHLACDEE 183
Query: 286 WGEELSFLELVVSSKKREARQILEQTPVK 314
EE FL +S E ++ E+TP++
Sbjct: 184 RVEEAKFLVTQGASIYIENKE--EKTPLQ 210
>4NIK-A nrPDB
Length = 230
Score = 116 bits (290), Expect = 4e-26, Method: Composition-based stats.
Identities = 52/214 (24%), Positives = 83/214 (38%), Gaps = 29/214 (13%)
Query: 53 AKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKEPALC 112
A L LK +L + TALH A + E L++ + +
Sbjct: 18 AYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDA- 76
Query: 113 EPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAAC 172
G + LHIA +V+ALL +GA V+A G PL +AA
Sbjct: 77 ----GWSPLHIAASAGRDEIVKALLGKGAQVNAVNQN-------------GCTPLHYAAS 119
Query: 173 VGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSL 232
EI +L+E GA+ A+D T +H + N +M ++LL Y ++
Sbjct: 120 KNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGN----LKMIHILLYYKASTN----- 170
Query: 233 ELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHV 266
+ + +G TP LA E + L+ + +
Sbjct: 171 --IQDTEGNTPLHLACDEERVEEAKLLVSQGASI 202
Score = 114 bits (286), Expect = 1e-25, Method: Composition-based stats.
Identities = 43/214 (20%), Positives = 76/214 (35%), Gaps = 32/214 (14%)
Query: 43 RIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAA 102
+ + L A +++ LL + G + LH+AA E L+
Sbjct: 42 QDSRTALHWACSAGHTEIVEFLLQL-GVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKG 100
Query: 103 PELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYY 162
++ G T LH A + LL GA+ A+ +Y
Sbjct: 101 AQVNAVNQN-----GCTPLHYAASKNRHEIAVMLLEGGANPDAKD-------------HY 142
Query: 163 GEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSY 222
+ AA G+ +++ +L+ + A QD+ GNT LH+ + A LL+S
Sbjct: 143 EATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEA----KLLVSQ 198
Query: 223 DEHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMF 256
+ N + TP ++A +G +
Sbjct: 199 GASIY-------IENKEEKTPLQVA--KGGLGLI 223
Score = 97.5 bits (241), Expect = 2e-20, Method: Composition-based stats.
Identities = 50/216 (23%), Positives = 77/216 (35%), Gaps = 27/216 (12%)
Query: 99 MEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHN 158
++ + K A +TALH A + +V LL G V+ +
Sbjct: 26 LKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDA--------- 76
Query: 159 LIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNL 218
G PL AA G +EIV+ L+ GA + A + G T LH + A +
Sbjct: 77 ----GWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAV----M 128
Query: 219 LLSYDEHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLY 278
LL + D E T A +GN M L+ + +T
Sbjct: 129 LLEGGANPDAKDHYEA-------TAMHRAAAKGNLKMIHILLYYKASTN-IQDTEGNTPL 180
Query: 279 DLTEIDSWGEELSFLELVVSSKKREARQILEQTPVK 314
L + EE L +S E ++ E+TP++
Sbjct: 181 HLACDEERVEEAKLLVSQGASIYIENKE--EKTPLQ 214
>5ET1-A nrPDB
Length = 353
Score = 105 bits (262), Expect = 7e-23, Method: Composition-based stats.
Identities = 48/237 (20%), Positives = 78/237 (32%), Gaps = 32/237 (13%)
Query: 43 RIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAA 102
R +P AA L L+ LL C Q++ G T LH+AA + + + L+
Sbjct: 69 RNGATPAHDAAATGYLSCLQWLLTQGGCRVQEKDNSGATVLHLAARFGHPDVVKWLLYQG 128
Query: 103 PELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGAS-VSARATGAAFRRSPHNLIY 161
+ G +H A +L ++ L+ V+A+
Sbjct: 129 ----GANSAITTDTGALPIHYAAAKGDLPSLKLLVGHYPEGVNAQTNN------------ 172
Query: 162 YGEHPLSFAACVGSEEIVRLLIEH-GADIRAQDSLGNTVLHILILQPNKTFACQMYNLLL 220
G PL A G E+ + L++ AD + G T LH + + L
Sbjct: 173 -GATPLYLACQEGHLEVTKYLVQECSADPHLRAQDGMTPLHAAAQMGHNPVL-----VWL 226
Query: 221 SYDEHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQ---WTCGPLT 274
+ +H G T A G+T + L+ + W PL
Sbjct: 227 VSFADVSFSEQ-----DHDGATAMHFAASRGHTKVLSWLLLHGAEISQDLWGGTPLH 278
Score = 102 bits (254), Expect = 6e-22, Method: Composition-based stats.
Identities = 40/169 (23%), Positives = 65/169 (38%), Gaps = 18/169 (10%)
Query: 41 QERIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLME 100
Q +PL A +E L + K L+ S D R G T LH AA + + +
Sbjct: 169 QTNNGATPLYLACQEGHLEVTKYLVQECSADPHLRAQDGMTPLHAAAQMGH-NPVLVWLV 227
Query: 101 AAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLI 160
+ +++ + G TA+H A + ++ LL GA +S
Sbjct: 228 SFADVSFSE---QDHDGATAMHFAASRGHTKVLSWLLLHGAEIS--------------QD 270
Query: 161 YYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNK 209
+G PL AA G E ++L +GA + +D G T + +
Sbjct: 271 LWGGTPLHDAAENGELECCQILAVNGAGLDVRDHDGYTAADLAEFNGHT 319
Score = 98.6 bits (244), Expect = 8e-21, Method: Composition-based stats.
Identities = 56/212 (26%), Positives = 88/212 (41%), Gaps = 28/212 (13%)
Query: 48 PLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAK 107
P+ AA + DL LK+L+ + + G T L++A +LE L++ E +
Sbjct: 142 PIHYAAAKGDLPSLKLLVGHYPEGVNAQTNNGATPLYLACQEGHLEVTKYLVQ---ECSA 198
Query: 108 EPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPL 167
+P L G T LH A + ++ L++ A VS F H+ G +
Sbjct: 199 DPHL-RAQDGMTPLHAAAQMGHNPVLVWLVSF-ADVS-------FSEQDHD----GATAM 245
Query: 168 SFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSD 227
FAA G +++ L+ HGA+I +QD G T LH + +L D
Sbjct: 246 HFAASRGHTKVLSWLLLHGAEI-SQDLWGGTPLHDAAENGE----LECCQILAVNGAGLD 300
Query: 228 HLQSLELVPNHQGLTPFKLAGVEGNTVMFQHL 259
V +H G T LA G+T ++L
Sbjct: 301 -------VRDHDGYTAADLAEFNGHTHCSRYL 325
Score = 91.3 bits (225), Expect = 1e-18, Method: Composition-based stats.
Identities = 49/214 (22%), Positives = 77/214 (35%), Gaps = 29/214 (13%)
Query: 50 LQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKEP 109
LQAA+ DL +L+ L R ++ +H AA L L+E P
Sbjct: 8 LQAARRGDLDVLRSLHAAGLLGPSLRDSLDALPVHHAARSGKLHCLRYLVEEVA----LP 63
Query: 110 ALCEPFVGQTALHIAVMNQNLNLVRALLARGAS-VSARATGAAFRRSPHNLIYYGEHPLS 168
A+ G T H A L+ ++ LL +G V + G L
Sbjct: 64 AVSRARNGATPAHDAAATGYLSCLQWLLTQGGCRVQEKDNS-------------GATVLH 110
Query: 169 FAACVGSEEIVRLLI-EHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSD 227
AA G ++V+ L+ + GA+ G +H + + L S
Sbjct: 111 LAARFGHPDVVKWLLYQGGANSAITTDTGALPIHYAAAKGD----------LPSLKLLVG 160
Query: 228 HLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQ 261
H + G TP LA EG+ + ++L+Q
Sbjct: 161 HYPEGVNAQTNNGATPLYLACQEGHLEVTKYLVQ 194
Score = 54.7 bits (130), Expect = 2e-07, Method: Composition-based stats.
Identities = 27/108 (25%), Positives = 39/108 (36%), Gaps = 7/108 (6%)
Query: 29 WEQYRDRVNMLQQERIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAAL 88
W V+ +Q+ + + AA ++L LLL + Q G T LH AA
Sbjct: 225 WLVSFADVSFSEQDHDGATAMHFAASRGHTKVLSWLLL-HGAEISQ-DLWGGTPLHDAAE 282
Query: 89 YDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRAL 136
LE +L L G TA +A N + + R L
Sbjct: 283 NGELECCQILAVNGAGLD-----VRDHDGYTAADLAEFNGHTHCSRYL 325
>3EU9-A nrPDB
Length = 240
Score = 101 bits (251), Expect = 1e-21, Method: Composition-based stats.
Identities = 52/218 (23%), Positives = 80/218 (36%), Gaps = 31/218 (14%)
Query: 49 LLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKE 108
L AA N + L+K + + Q G + T LH A +L LM+ + +
Sbjct: 46 LHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLI 105
Query: 109 PALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLS 168
G + +H+A + ++V L+A+G V G PL
Sbjct: 106 DG-----EGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQN-------------GMTPLM 147
Query: 169 FAACVGS-EEIVRLLIEHGADIRAQDSL-GNTVLHILILQPNKTFACQMYNLLLSYDEHS 226
+AA + RLL+ + D NT LH +L N T +LLL +
Sbjct: 148 WAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVI----SLLLEAGANV 203
Query: 227 DHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRK 264
D N +G + LA N M HL + R+
Sbjct: 204 DAQ-------NIKGESALDLAKQRKNVWMINHLQEARQ 234
Score = 101 bits (251), Expect = 1e-21, Method: Composition-based stats.
Identities = 34/172 (19%), Positives = 65/172 (37%), Gaps = 19/172 (11%)
Query: 47 SPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELA 106
+PL A ++ L ++ L+ D G + +H+AA + + L+ ++
Sbjct: 78 TPLHWATRQGHLSMVVQLMKY-GADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVD 136
Query: 107 KEPALCEPFVGQTALHIAVMNQN-LNLVRALLARGASVSARATGAAFRRSPHNLIYYGEH 165
G T L A + ++ R LL SV+ Y+
Sbjct: 137 MMDQN-----GMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDK------------YHKNT 179
Query: 166 PLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYN 217
L +A G+ ++ LL+E GA++ AQ+ G + L + + N +
Sbjct: 180 ALHWAVLAGNTTVISLLLEAGANVDAQNIKGESALDLAKQRKNVWMINHLQE 231
Score = 67.8 bits (164), Expect = 2e-11, Method: Composition-based stats.
Identities = 34/168 (20%), Positives = 62/168 (36%), Gaps = 28/168 (16%)
Query: 85 VAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVS 144
A Y E L+EA ++ + T LH A +N ++LV+ +++GA V
Sbjct: 15 KATQYGIYERCRELVEAGYDVRQPDK-----ENVTLLHWAAINNRIDLVKYYISKGAIVD 69
Query: 145 ARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILI 204
PL +A G +V L+++GAD D G + +H+
Sbjct: 70 ------------QLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAA 117
Query: 205 LQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQGLTPFKLAGVEGN 252
+ + L++ + D + + G+TP A +
Sbjct: 118 QFGHTSIVAY----LIAKGQDVD-------MMDQNGMTPLMWAAYRTH 154
Score = 53.6 bits (127), Expect = 3e-07, Method: Composition-based stats.
Identities = 30/148 (20%), Positives = 48/148 (32%), Gaps = 31/148 (20%)
Query: 124 AVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLI 183
A R L+ G V L +AA ++V+ I
Sbjct: 16 ATQYGIYERCRELVEAGYDVRQPDKENV-------------TLLHWAAINNRIDLVKYYI 62
Query: 184 EHGADIRAQDSLG----NTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQ 239
GA + D LG +T LH Q + + Q L+ Y + +
Sbjct: 63 SKGAIV---DQLGGDLNSTPLHWATRQGHLSMVVQ----LMKYGADPSLIDG-------E 108
Query: 240 GLTPFKLAGVEGNTVMFQHLMQKRKHVQ 267
G + LA G+T + +L+ K + V
Sbjct: 109 GCSCIHLAAQFGHTSIVAYLIAKGQDVD 136
>3ZKJ-A nrPDB
Length = 261
Score = 96.3 bits (238), Expect = 4e-20, Method: Composition-based stats.
Identities = 44/222 (19%), Positives = 74/222 (33%), Gaps = 32/222 (14%)
Query: 47 SPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELA 106
SP+ +AA L+ L+ Q A + LH A L +L +L++ ++
Sbjct: 5 SPMHEAAIHGHQLSLRNLIS-QGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQVN 63
Query: 107 KEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHP 166
A T L A ++ + + V LL GASV + P
Sbjct: 64 GVTADW-----HTPLFNACVSGSWDCVNLLLQHGASVQPESDL--------------ASP 104
Query: 167 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHS 226
+ AA G E V LI +G +I + S T L++ + + LL
Sbjct: 105 IHEAARRGHVECVNSLIAYGGNIDHKISHLGTPLYLACENQQRACVKK----LLESGADV 160
Query: 227 DHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQW 268
+ + + +P + + LM Q
Sbjct: 161 NQGKGQD--------SPLHAVARTASEELACLLMDFGADTQA 194
Score = 84.0 bits (206), Expect = 2e-16, Method: Composition-based stats.
Identities = 44/193 (22%), Positives = 75/193 (38%), Gaps = 32/193 (16%)
Query: 80 ETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLAR 139
+ +H AA++ + + L+ + A + LH A + +L+ V+ LL
Sbjct: 4 WSPMHEAAIHGHQLSLRNLISQGWAVNIITADH-----VSPLHEACLGGHLSCVKILLKH 58
Query: 140 GASVS-ARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNT 198
GA V+ A PL A GS + V LL++HGA ++ + L +
Sbjct: 59 GAQVNGVTADWH--------------TPLFNACVSGSWDCVNLLLQHGASVQPESDLA-S 103
Query: 199 VLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQH 258
+H + + + N L++Y + DH S H G TP LA +
Sbjct: 104 PIHEAARRGH----VECVNSLIAYGGNIDHKIS------HLG-TPLYLACENQQRACVKK 152
Query: 259 LMQKRKHVQWTCG 271
L++ V G
Sbjct: 153 LLESGADVNQGKG 165
>5OEO-C nrPDB
Length = 73
Score = 95.2 bits (235), Expect = 9e-20, Method: Composition-based stats.
Identities = 55/73 (75%), Positives = 61/73 (83%), Gaps = 1/73 (1%)
Query: 654 SDKEDGQEQLSEKRPSTVESGMLSRASVAFQTPSLSRTTSQSSNSHRGWEILRRNTLGHL 713
+DKED QE SEK+PS ESG L+RAS+A T SLSRT SQSS SHRGWEILR+NTLGHL
Sbjct: 2 ADKEDDQEHPSEKQPSGAESGTLARASLALPTSSLSRTASQSS-SHRGWEILRQNTLGHL 60
Query: 714 NLGLDLGEGDGEE 726
NLGL+L EGDGEE
Sbjct: 61 NLGLNLSEGDGEE 73
>6CUD-A nrPDB
Length = 806
Score = 94.0 bits (232), Expect = 2e-19, Method: Composition-based stats.
Identities = 96/679 (14%), Positives = 199/679 (29%), Gaps = 154/679 (22%)
Query: 46 DSPLLQAAKENDLRLLKILLL-NQSCDFQQRGAVGETALHVAALYDNLE----------- 93
+ L AA+ ++ +++ +L +++ + +G+ AL +A ++LE
Sbjct: 28 EERFLDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENL 87
Query: 94 -----------------AATLLMEAAP--------------ELAKEPALCEPFVGQ---- 118
++ EL + G
Sbjct: 88 ARIGDALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAYDEDGTRFSP 147
Query: 119 --TALHIAVMNQNLNLVRALLARGASVSARA-----TGAAFRRSPHNLI---------YY 162
T + +A Q +V LL +GA + G + H+ Y
Sbjct: 148 DITPIILAAHCQKYEVVHMLLMKGARIERPHDYFCKCGDCMEKQRHDSFSHSRSRINAYK 207
Query: 163 G-EHPLSFAACVGSEEIVRLLIEHG-ADIRAQDSLGNTVLHILILQPNKTFACQMYNLL- 219
G P + + L + + A + + L +Q K F + +L
Sbjct: 208 GLASPAYLSLSSEDPVLTALELSNELAKLANIEKEFKNDYRKLSMQC-KDFVVGVLDLCR 266
Query: 220 ------LSYDEHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPL 273
+ + + LE+ + L+ KLA + + + H L
Sbjct: 267 DSEEVEAILNGDLESAEPLEVHRHKASLSRVKLAI---KYEVKKFV----AHPNCQQQLL 319
Query: 274 TSTLYDLTEIDSWGEELSFL-ELVVSSKKREARQILEQTPVKELVSFKW----KKYGR-- 326
T W E LS L E ++ K + P L W + G+
Sbjct: 320 TI----------WYENLSGLREQTIAIKCLVVLVVALGLPF--LAIGYWIAPCSRLGKIL 367
Query: 327 PYFCVLASLYILYMICFTTCCIYRPLKLRDDNRTDPRDITILQQKLLQEAYVTHQDNIRL 386
+ + I F ++ + T P K + T
Sbjct: 368 RSPFMKFVAHAASFIIFLGLLVFNASDRFEGITTLPNITVTDYPKQIFRVKTTQFTWT-- 425
Query: 387 VGELVTVTGAVIILLLEIPDIFRVGASRYFGQ----------TILGGPF--HVIIITYAS 434
E++ + + ++ E +++ G Y Q +I F + A+
Sbjct: 426 --EMLIMVWVLGMMWSECKELWLEGPREYILQLWNVLDFGMLSIFIAAFTARFLAFLQAT 483
Query: 435 -----------------LVLLTMVMRLT-NMNGEVV---------PLSFALVLGWCSVMY 467
+ L + T + + + A+VL + + Y
Sbjct: 484 KAQQYVDSYVQESDLSEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSRIAY 543
Query: 468 FARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFHITFQTEDPNNLGEFSDYP 527
+ GP I + + + D+ +F L +V F I + + +
Sbjct: 544 ILPANESFGPLQISLGRTV-KDIFKFMVLFIMVFFAFMIGMFILYSY---YLGAKVNAAF 599
Query: 528 TALFSTFELFLTIIDGP-----ANYSVDLPFM---YCITYAAFAIIATLLMLNLFIAMMG 579
T + +F+ I G D F+ + Y + + +++LN+ IAM+
Sbjct: 600 TTVEESFKTLFWSIFGLSEVTSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLNMLIAMIN 659
Query: 580 DTHWRVAQERDELWRAQVV 598
++ + + D W+
Sbjct: 660 SSYQEIEDDSDVEWKFARS 678
>4OT9-A nrPDB
Length = 359
Score = 93.6 bits (231), Expect = 3e-19, Method: Composition-based stats.
Identities = 39/179 (21%), Positives = 65/179 (36%), Gaps = 25/179 (13%)
Query: 46 DSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVA--ALYDNLEAATLLMEAAP 103
+PL A ++ LL D G++A+H+A A E L+++
Sbjct: 122 QTPLHLAVITGQTSVVSFLLRV-GADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGA 180
Query: 104 ELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATG-------------- 149
+ F G +H+AV ++ + L+ GA V A
Sbjct: 181 PAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEE 240
Query: 150 --------AAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVL 200
R + + + G PL AA +G + RLL++ GADI A++ L
Sbjct: 241 LGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPL 299
Score = 89.8 bits (221), Expect = 4e-18, Method: Composition-based stats.
Identities = 55/264 (20%), Positives = 97/264 (36%), Gaps = 35/264 (13%)
Query: 38 MLQQERIRDSPLLQAAKENDLRLLKILL-----LNQSCDFQQRGAVGETALHVAALYDNL 92
+ Q+ D+PL A +++ ++ + +T LH+A +
Sbjct: 75 LTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQT 134
Query: 93 EAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNL--NLVRALLARGASVSARATGA 150
+ L+ + PAL + G +A+H+A+ L+RALL GA
Sbjct: 135 SVVSFLLRVGAD----PALLDRH-GDSAMHLALRAGAGAPELLRALLQSGA--------P 181
Query: 151 AFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSL-GNTVLHILILQPNK 209
A + H + G +P+ A S E + LL++ GA++ A + G T LH+
Sbjct: 182 AVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEEL 241
Query: 210 TFACQMYNLLLSYDEHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQWT 269
+ L + + G TP LA G + + L++ +
Sbjct: 242 GLVTHLVTKL---RANVNA-------RTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAE 291
Query: 270 CG----PLTSTLYDLTEIDSWGEE 289
PL S ++ DS G E
Sbjct: 292 NEEPLCPLPSPPTSDSDSDSEGPE 315
Score = 77.8 bits (190), Expect = 1e-14, Method: Composition-based stats.
Identities = 42/206 (20%), Positives = 77/206 (37%), Gaps = 16/206 (7%)
Query: 111 LCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFA 170
+ G T LH+A+++ +++ ++ A+ G + + + PL A
Sbjct: 76 TAQDENGDTPLHLAIIHGQTSVIEQIVY--VIHHAQDLGVVNLTNHLH-----QTPLHLA 128
Query: 171 ACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQ 230
G +V L+ GAD D G++ +H+ + A ++ LL +
Sbjct: 129 VITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAG--AGAPELLRALLQSGAPAVP-- 184
Query: 231 SLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSWGEEL 290
L +P+ +GL P LA + L+ V+ T T L + EEL
Sbjct: 185 QLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLA---TEMEEL 241
Query: 291 SFLELVVSS--KKREARQILEQTPVK 314
+ +V+ AR TP+
Sbjct: 242 GLVTHLVTKLRANVNARTFAGNTPLH 267
Score = 50.1 bits (118), Expect = 3e-06, Method: Composition-based stats.
Identities = 24/125 (19%), Positives = 40/125 (32%), Gaps = 28/125 (22%)
Query: 41 QERIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLME 100
+ + + L A + +L L+ L+ + R G T LH+AA LL++
Sbjct: 224 ERQGGRTALHLATEMEELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLK 283
Query: 101 AAPELAKEPALC------------------------EPFVGQTALHIAVMNQNLNLVRAL 136
A ++ E F G T L + + V+ L
Sbjct: 284 AGADIHAENEEPLCPLPSPPTSDSDSDSEGPEKDTRSSFRGHTPLDLTCSTK----VKTL 339
Query: 137 LARGA 141
L A
Sbjct: 340 LLNAA 344
>1BD8-A nrPDB
Length = 156
Score = 90.5 bits (223), Expect = 2e-18, Method: Composition-based stats.
Identities = 31/165 (18%), Positives = 61/165 (36%), Gaps = 20/165 (12%)
Query: 52 AAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKEPAL 111
AA D++ ++ LL + G+TAL V ++ + A L++
Sbjct: 9 AAARGDVQEVRRLLHRELVHPDALNRFGKTALQV-MMFGSTAIALELLKQGASPN----- 62
Query: 112 CEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAA 171
+ G + +H A L+ ++ L+ GA V+ G P+ A
Sbjct: 63 VQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGT-------------GALPIHLAV 109
Query: 172 CVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMY 216
G +V L +D+ +D+ G T L + + + + +
Sbjct: 110 QEGHTAVVSFL-AAESDLHRRDARGLTPLELALQRGAQDLVDILQ 153
Score = 64.7 bits (156), Expect = 1e-10, Method: Composition-based stats.
Identities = 26/121 (21%), Positives = 43/121 (35%), Gaps = 19/121 (15%)
Query: 65 LLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIA 124
LL Q + G + +H AA L+ +L+E ++ G +H+A
Sbjct: 54 LLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGT-----GALPIHLA 108
Query: 125 VMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIE 184
V + +V L A H G PL A G++++V +L
Sbjct: 109 VQEGHTAVVSFLAA--------------ESDLHRRDARGLTPLELALQRGAQDLVDILQG 154
Query: 185 H 185
H
Sbjct: 155 H 155
Score = 64.0 bits (154), Expect = 2e-10, Method: Composition-based stats.
Identities = 21/90 (23%), Positives = 33/90 (36%), Gaps = 7/90 (7%)
Query: 47 SPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELA 106
SP+ AA+ L LK+L+ D G +H+A + + L A
Sbjct: 70 SPVHDAARTGFLDTLKVLVE-HGADVNVPDGTGALPIHLAVQEGHTAVVSFL------AA 122
Query: 107 KEPALCEPFVGQTALHIAVMNQNLNLVRAL 136
+ G T L +A+ +LV L
Sbjct: 123 ESDLHRRDARGLTPLELALQRGAQDLVDIL 152
>1WG0-A nrPDB
Length = 243
Score = 89.8 bits (221), Expect = 4e-18, Method: Composition-based stats.
Identities = 44/205 (21%), Positives = 73/205 (35%), Gaps = 23/205 (11%)
Query: 48 PLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAK 107
PL QA EN+ ++ LL ++ Q+ G LH + + E + L+ +
Sbjct: 5 PLHQACMENEFFKVQELLHSKPSLLLQKDQDGRIPLHWSVSFQAHEITSFLLSKMENVNL 64
Query: 108 EPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPL 167
+ + G T HIA NL +V++L R + + + G L
Sbjct: 65 DDYPDDS--GWTPFHIACSVGNLEVVKSLYDR-----------PLKPDLNKITNQGVTCL 111
Query: 168 SFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSD 227
A E+ + LIE+GA +R +D LH + +
Sbjct: 112 HLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHRAASVGSLKLIELL-------CGLGK 164
Query: 228 HLQSLELVPNHQGLTPFKLAGVEGN 252
+ + QG TP A EG+
Sbjct: 165 SAVNWQD---KQGWTPLFHALAEGH 186
Score = 80.1 bits (196), Expect = 3e-15, Method: Composition-based stats.
Identities = 43/197 (21%), Positives = 74/197 (37%), Gaps = 22/197 (11%)
Query: 38 MLQQERIRDSPLLQAAKENDLRLLKILL-LNQSCDFQQ-RGAVGETALHVAALYDNLEAA 95
+LQ+++ PL + + LL ++ + G T H+A NLE
Sbjct: 29 LLQKDQDGRIPLHWSVSFQAHEITSFLLSKMENVNLDDYPDDSGWTPFHIACSVGNLEVV 88
Query: 96 TLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRS 155
L + + + G T LH+AV + + + L+ GASV +
Sbjct: 89 KSLYDRPLKPDLNKITNQ---GVTCLHLAVGKKWFEVSQFLIENGASVRIKDK------- 138
Query: 156 PHNLIYYGEHPLSFAACVGSEEIVRLLIEHGAD-IRAQDSLGNTVLHILILQPNKTFACQ 214
+ + PL AA VGS +++ LL G + QD G T L + + + A
Sbjct: 139 ------FNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVL 192
Query: 215 MYNLLLSYDEHSDHLQS 231
+ Y D + +
Sbjct: 193 LVE---KYGAEYDLVDN 206
Score = 45.5 bits (106), Expect = 9e-05, Method: Composition-based stats.
Identities = 41/178 (23%), Positives = 71/178 (39%), Gaps = 23/178 (12%)
Query: 166 PLSFAACVGSE-EIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDE 224
PL A ++ LL + + +D G LH + A ++ + LLS E
Sbjct: 5 PLHQACMENEFFKVQELLHSKPSLLLQKDQDGRIPLHWSVSFQ----AHEITSFLLSKME 60
Query: 225 HSDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEID 284
+ + L+ P+ G TPF +A GN + + L + PL DL +I
Sbjct: 61 NVN----LDDYPDDSGWTPFHIACSVGNLEVVKSLYDR---------PLKP---DLNKIT 104
Query: 285 SWGEELSFLELVVSSKKREARQILEQTPVKELVSFKWKKYGRPYFCVLASLYILYMIC 342
+ G ++ L L V K E Q L + + K+ + + SL ++ ++C
Sbjct: 105 NQG--VTCLHLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHRAASVGSLKLIELLC 160
>6CV9-A nrPDB
Length = 842
Score = 86.3 bits (212), Expect = 5e-17, Method: Composition-based stats.
Identities = 28/168 (16%), Positives = 65/168 (38%), Gaps = 17/168 (10%)
Query: 455 SFALVLGWCSVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASA-FHITFQ 513
+ A+VL + + Y + GP I + + + D+ +F + +V + F F++
Sbjct: 511 AIAVVLSFSRIAYILPANESFGPLQISLGRTV-KDIFKFMVIFIMVFVAFMIGMFNLYSY 569
Query: 514 TEDPNNLGEFSDYPTALFSTFELFLTIIDGP-------ANYSVDL-PFMYCITYAAFAII 565
+ ++ T + +F+ I G NY+ + + Y + +
Sbjct: 570 YIG----AKQNEAFTTVEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGYVLYGVYNVT 625
Query: 566 ATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVA---TTVMLERKMPR 610
+++LN+ IAM+ + + + D W+ + R +P
Sbjct: 626 MVIVLLNMLIAMINSSFQEIEDDADVEWKFARAKLWFSYFEEGRTLPV 673
Score = 57.4 bits (137), Expect = 2e-08, Method: Composition-based stats.
Identities = 31/161 (19%), Positives = 58/161 (36%), Gaps = 23/161 (14%)
Query: 44 IRDSPLLQAAKENDLRLLKILLLN-QSCDFQQRGAVGETALHVAALYDNLEAATLLMEAA 102
I + L AA+ ++ +++ +L S + +G+ AL +A ++LE LL++
Sbjct: 8 IEEERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKK- 66
Query: 103 PELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGA------------SVSARATGA 150
+ + AL +A+ + +V A+L A +
Sbjct: 67 ----ENLSRVGD-----ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDF 117
Query: 151 AFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRA 191
+ P+ AA EIV L+ GA I
Sbjct: 118 YAYDEDGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIER 158
Score = 53.6 bits (127), Expect = 3e-07, Method: Composition-based stats.
Identities = 35/193 (18%), Positives = 57/193 (29%), Gaps = 40/193 (20%)
Query: 83 LHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGAS 142
AA Y N+ ++E L C ++GQ AL +AV N++L + LL +
Sbjct: 13 FLDAAEYGNIPVVRKMLEECHSLN---VNCVDYMGQNALQLAVANEHLEITELLLKKE-- 67
Query: 143 VSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHI 202
+ G L A G IV ++ H A
Sbjct: 68 -NLSRVGD---------------ALLLAISKGYVRIVEAILNHPA--------------- 96
Query: 203 LILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQK 262
K A L D+ + + +TP LA + L++K
Sbjct: 97 --FAEGKRLATSPSQSELQQDDFYAYDED--GTRFSHDVTPIILAAHCQEYEIVHTLLRK 152
Query: 263 RKHVQWTCGPLTS 275
++
Sbjct: 153 GARIERPHDYFCK 165
>1BLX-B nrPDB
Length = 166
Score = 83.2 bits (204), Expect = 4e-16, Method: Composition-based stats.
Identities = 37/174 (21%), Positives = 67/174 (38%), Gaps = 20/174 (11%)
Query: 38 MLQQERIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATL 97
ML +E L AA D++ ++ LL + G+TAL V ++ + A
Sbjct: 1 MLLEEVCVGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQV-MMFGSPAVALE 59
Query: 98 LMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPH 157
L++ + A G + +H A L+ ++ L+ GA V+A +
Sbjct: 60 LLKQGASPNVQDAS-----GTSPVHDAARTGFLDTLKVLVEHGADVNALDST-------- 106
Query: 158 NLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTF 211
G P+ A G +V L +D+ +D+ G T L + + +
Sbjct: 107 -----GSLPIHLAIREGHSSVVSFLAPE-SDLHHRDASGLTPLELARQRGAQNL 154
Score = 61.3 bits (147), Expect = 2e-09, Method: Composition-based stats.
Identities = 25/121 (20%), Positives = 47/121 (38%), Gaps = 19/121 (15%)
Query: 65 LLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIA 124
LL Q + A G + +H AA L+ +L+E ++ + G +H+A
Sbjct: 60 LLKQGASPNVQDASGTSPVHDAARTGFLDTLKVLVEHGADVNALDST-----GSLPIHLA 114
Query: 125 VMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIE 184
+ + ++V L A + + R G PL A G++ ++ +L
Sbjct: 115 IREGHSSVVSFL-APESDLHHRDAS-------------GLTPLELARQRGAQNLMDILQG 160
Query: 185 H 185
H
Sbjct: 161 H 161
Score = 59.3 bits (142), Expect = 5e-09, Method: Composition-based stats.
Identities = 20/90 (22%), Positives = 32/90 (35%), Gaps = 7/90 (7%)
Query: 47 SPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELA 106
SP+ AA+ L LK+L+ D + G +H+A + + L
Sbjct: 76 SPVHDAARTGFLDTLKVLVE-HGADVNALDSTGSLPIHLAIREGHSSVVSFL------AP 128
Query: 107 KEPALCEPFVGQTALHIAVMNQNLNLVRAL 136
+ G T L +A NL+ L
Sbjct: 129 ESDLHHRDASGLTPLELARQRGAQNLMDIL 158
>3LJN-A nrPDB
Length = 364
Score = 77.4 bits (189), Expect = 2e-14, Method: Composition-based stats.
Identities = 45/243 (18%), Positives = 84/243 (34%), Gaps = 28/243 (11%)
Query: 48 PLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAK 107
+ AA++ ++ L+ + G TALH+A + ++ A L
Sbjct: 23 KIHVAARKGQTDEVRRLIET-GVSPTIQNRFGCTALHLACKFGCVDTAKYLASVG----- 76
Query: 108 EPALCEPFVGQTALHIAVMNQNLNLVRALLARGAS---------VSARATGAAFRRSPHN 158
+ + GQ +H+AVM +LV AL+ GA ++ H
Sbjct: 77 --EVHSLWHGQKPIHLAVMANKTDLVVALVE-GAKERGQMPESLLNECDEREVNEIGSHV 133
Query: 159 LIYYGEHPLSFAACVG--SEEIVRLLIEHGADIRAQDSLGNTVLHILI-LQPNKTFACQM 215
G+ L + +G E++++L++ GA A+D T L + + + M
Sbjct: 134 KHCKGQTALHWCVGLGPEYLEMIKILVQLGASPTAKDKADETPLMRAMEFRNREALDLMM 193
Query: 216 YNLLLSYDEHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTS 275
+ D+ N QG + A + + ++ V T
Sbjct: 194 DTVPSKSSLRLDYA-------NKQGNSHLHWAILINWEDVAMRFVEMGIDVNMEDNEHTV 246
Query: 276 TLY 278
LY
Sbjct: 247 PLY 249
Score = 60.9 bits (146), Expect = 2e-09, Method: Composition-based stats.
Identities = 39/207 (18%), Positives = 70/207 (33%), Gaps = 46/207 (22%)
Query: 41 QERIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLME 100
Q R + L A K + K L G+ +H+A + + + L+E
Sbjct: 49 QNRFGCTALHLACKFGCVDTAKYLASVGEVH---SLWHGQKPIHLAVMANKTDLVVALVE 105
Query: 101 AAPE----------------LAKEPALCEPFVGQTALHIAVMNQ--NLNLVRALLARGAS 142
A E + + + + GQTALH V L +++ L+ GAS
Sbjct: 106 GAKERGQMPESLLNECDEREVNEIGSHVKHCKGQTALHWCVGLGPEYLEMIKILVQLGAS 165
Query: 143 VSARATGA----------------------AFRRSPHNLIYY---GEHPLSFAACVGSEE 177
+A+ +S L Y G L +A + E+
Sbjct: 166 PTAKDKADETPLMRAMEFRNREALDLMMDTVPSKSSLRLDYANKQGNSHLHWAILINWED 225
Query: 178 IVRLLIEHGADIRAQDSLGNTVLHILI 204
+ +E G D+ +D+ L++ +
Sbjct: 226 VAMRFVEMGIDVNMEDNEHTVPLYLSV 252
>1G3N-B nrPDB
Length = 168
Score = 70.1 bits (170), Expect = 3e-12, Method: Composition-based stats.
Identities = 32/138 (23%), Positives = 51/138 (36%), Gaps = 18/138 (13%)
Query: 50 LQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKEP 109
LQ K + + + LLL + + G +H AA L+ L+E ++
Sbjct: 42 LQVMKLGNPEIARRLLLR-GANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVN--- 97
Query: 110 ALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSF 169
E G LH+A +L +V L+ AS G + G+
Sbjct: 98 --IEDNEGNLPLHLAAKEGHLRVVEFLVKHTAS----NVGHRNHK--------GDTACDL 143
Query: 170 AACVGSEEIVRLLIEHGA 187
A G E+V L+ +GA
Sbjct: 144 ARLYGRNEVVSLMQANGA 161
Score = 64.7 bits (156), Expect = 2e-10, Method: Composition-based stats.
Identities = 23/93 (24%), Positives = 34/93 (36%), Gaps = 5/93 (5%)
Query: 49 LLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKE 108
+ AA+ L L+ LL Q D G LH+AA +L L++
Sbjct: 74 IHDAARAGFLDTLQTLLEFQ-ADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGH 132
Query: 109 PALCEPFVGQTALHIAVMNQNLNLVRALLARGA 141
G TA +A + +V + A GA
Sbjct: 133 R----NHKGDTACDLARLYGRNEVVSLMQANGA 161
Score = 64.4 bits (155), Expect = 2e-10, Method: Composition-based stats.
Identities = 40/174 (22%), Positives = 66/174 (37%), Gaps = 29/174 (16%)
Query: 83 LHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGAS 142
L AA +LE T L++ + + G+TAL + + N + R LL RGA+
Sbjct: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGF-----GRTALQV-MKLGNPEIARRLLLRGAN 62
Query: 143 VSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHI 202
+ G + AA G + ++ L+E AD+ +D+ GN LH+
Sbjct: 63 PDLKDRT-------------GFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHL 109
Query: 203 LILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMF 256
+ + + H S NH+G T LA + G +
Sbjct: 110 AAKEGHLRVVEFLVK----------HTASNVGHRNHKGDTACDLARLYGRNEVV 153
Score = 55.5 bits (132), Expect = 9e-08, Method: Composition-based stats.
Identities = 27/133 (20%), Positives = 49/133 (36%), Gaps = 12/133 (9%)
Query: 162 YGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLS 221
+G L +G+ EI R L+ GA+ +D G V+H LL
Sbjct: 37 FGRTALQVMK-LGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAG----FLDTLQTLLE 91
Query: 222 YDEHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLT 281
+ + + +++G P LA EG+ + + L++ T DL
Sbjct: 92 FQADVN-------IEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLA 144
Query: 282 EIDSWGEELSFLE 294
+ E +S ++
Sbjct: 145 RLYGRNEVVSLMQ 157
Score = 42.4 bits (98), Expect = 6e-04, Method: Composition-based stats.
Identities = 18/56 (32%), Positives = 29/56 (51%)
Query: 48 PLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAP 103
PL AAKE LR+++ L+ + + + R G+TA +A LY E +L+
Sbjct: 106 PLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161
>5DND-A nrPDB
Length = 588
Score = 69.0 bits (167), Expect = 7e-12, Method: Composition-based stats.
Identities = 36/171 (21%), Positives = 60/171 (35%), Gaps = 18/171 (10%)
Query: 50 LQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKEP 109
L A +L L+ L+ D + + + G+T LHVAA T+L+ ++
Sbjct: 427 LALAHAGELEALQALMEL-GSDLRLKDSNGQTLLHVAARNGRDGVVTMLLHRGMDVN--- 482
Query: 110 ALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSF 169
G + L +AV ++ +R L GA +S + A L
Sbjct: 483 --ARDRDGLSPLLLAVQGRHRECIRLLRKAGACLSPQDLKDAGTELCRLASRADMEGLQ- 539
Query: 170 AACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLL 220
G GAD++ G + L + N+ + NL L
Sbjct: 540 --AWGQA---------GADLQQPGYDGRSALCVAEAAGNQEVLALLRNLAL 579
Score = 50.5 bits (119), Expect = 3e-06, Method: Composition-based stats.
Identities = 28/146 (19%), Positives = 52/146 (35%), Gaps = 18/146 (12%)
Query: 37 NMLQQERIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAAT 96
++ ++ + L AA+ ++ +LL D R G + L +A + E
Sbjct: 447 DLRLKDSNGQTLLHVAARNGRDGVVTMLLHR-GMDVNARDRDGLSPLLLAVQGRHRECIR 505
Query: 97 LLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSP 156
LL +A L+ + T L ++ ++A GA +
Sbjct: 506 LLRKAGACLSPQDLKDAG----TELCRLASRADMEGLQAWGQAGADLQ------------ 549
Query: 157 HNLIYYGEHPLSFAACVGSEEIVRLL 182
Y G L A G++E++ LL
Sbjct: 550 -QPGYDGRSALCVAEAAGNQEVLALL 574
Score = 48.6 bits (114), Expect = 1e-05, Method: Composition-based stats.
Identities = 32/191 (16%), Positives = 63/191 (32%), Gaps = 25/191 (13%)
Query: 107 KEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHP 166
+E ++ + + AL +A L ++AL+ G+ + + + G+
Sbjct: 413 EEDSVQDAVMPSLALALA-HAGELEALQALMELGSDLRLKDSN-------------GQTL 458
Query: 167 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHS 226
L AA G + +V +L+ G D+ A+D G + L + + ++ LL
Sbjct: 459 LHVAARNGRDGVVTMLLHRGMDVNARDRDGLSPLLLAVQGRHRECI----RLLRKAGACL 514
Query: 227 DHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSW 286
T + Q Q +Q G + + E
Sbjct: 515 SPQDL------KDAGTELCRLASRADMEGLQAWGQAGADLQ-QPGYDGRSALCVAEAAGN 567
Query: 287 GEELSFLELVV 297
E L+ L +
Sbjct: 568 QEVLALLRNLA 578
>6EMK-G nrPDB
Length = 426
Score = 68.2 bits (165), Expect = 1e-11, Method: Composition-based stats.
Identities = 38/161 (23%), Positives = 68/161 (42%), Gaps = 16/161 (9%)
Query: 49 LLQAAKENDLRLLKILLL-NQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAK 107
L +A E +L ++K LL N G ++LH A+ + L++ +
Sbjct: 9 LREAIIEGNLLIVKRLLRRNPDLLTNIDSENGWSSLHYASYHGRYLICVYLIQLGHD--- 65
Query: 108 EPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPL 167
+ L + F G T +H+A+M + + LL + F R ++ G P+
Sbjct: 66 KHELIKTFKGNTCVHLALMKGHEQTLHLLLQQ------------FPRFINHRGENGRAPI 113
Query: 168 SFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPN 208
A + + LLI GAD+ D+ G+T LH+ + +
Sbjct: 114 HIACMNDYYQCLSLLIGVGADLWVMDTNGDTPLHVCLEYGS 154
Score = 61.3 bits (147), Expect = 1e-09, Method: Composition-based stats.
Identities = 35/186 (18%), Positives = 61/186 (32%), Gaps = 25/186 (13%)
Query: 47 SPLLQAAKENDLRLLKILLL-NQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPEL 105
S L A+ + L+ + G T +H+A + + + LL++ P
Sbjct: 42 SSLHYASYHGRYLICVYLIQLGHDKHELIKTFKGNTCVHLALMKGHEQTLHLLLQQFPRF 101
Query: 106 AKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEH 165
G+ +HIA MN + L+ GA + T G+
Sbjct: 102 INHRGE----NGRAPIHIACMNDYYQCLSLLIGVGADLWVMDTN-------------GDT 144
Query: 166 PLSFAACVGSEEIVRLLIEHGA---DIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSY 222
PL GS +++L+ G D +D GN I +Y+ +L
Sbjct: 145 PLHVCLEYGSISCMKMLLNEGEVSLDDNVRDK-GN---WKPIDVAQTFEVGNIYSKVLKE 200
Query: 223 DEHSDH 228
+
Sbjct: 201 VKKKGP 206
Score = 58.2 bits (139), Expect = 1e-08, Method: Composition-based stats.
Identities = 32/183 (17%), Positives = 60/183 (32%), Gaps = 26/183 (14%)
Query: 83 LHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGAS 142
L A + NL L+ P+L + G ++LH A + + L+ G
Sbjct: 9 LREAIIEGNLLIVKRLLRRNPDL---LTNIDSENGWSSLHYASYHGRYLICVYLIQLGHD 65
Query: 143 VSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEH-GADIRAQDSLGNTVLH 201
+ + G + A G E+ + LL++ I + G +H
Sbjct: 66 -----------KHELIKTFKGNTCVHLALMKGHEQTLHLLLQQFPRFINHRGENGRAPIH 114
Query: 202 ILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQ 261
I + Q +LL+ V + G TP + G+ + L+
Sbjct: 115 IACMN----DYYQCLSLLIGVGADL-------WVMDTNGDTPLHVCLEYGSISCMKMLLN 163
Query: 262 KRK 264
+ +
Sbjct: 164 EGE 166
Score = 37.8 bits (86), Expect = 0.019, Method: Composition-based stats.
Identities = 14/60 (23%), Positives = 22/60 (36%), Gaps = 1/60 (1%)
Query: 43 RIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAA 102
+P+ A ND LL+ D G+T LHV Y ++ +L+
Sbjct: 107 ENGRAPIHIAC-MNDYYQCLSLLIGVGADLWVMDTNGDTPLHVCLEYGSISCMKMLLNEG 165
Score = 31.6 bits (70), Expect = 1.2, Method: Composition-based stats.
Identities = 27/130 (20%), Positives = 52/130 (40%), Gaps = 13/130 (10%)
Query: 167 LSFAACVGSEEIVRLLIEHGADI--RAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDE 224
L A G+ IV+ L+ D+ G + LH + + +Y + L +D+
Sbjct: 9 LREAIIEGNLLIVKRLLRRNPDLLTNIDSENGWSSLHYA--SYHGRYLICVYLIQLGHDK 66
Query: 225 HSDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQK-RKHVQWTCGPLTSTLYDLTEI 283
H EL+ +G T LA ++G+ L+Q+ + + G + +
Sbjct: 67 H-------ELIKTFKGNTCVHLALMKGHEQTLHLLLQQFPRFIN-HRGENGRAPIHIACM 118
Query: 284 DSWGEELSFL 293
+ + + LS L
Sbjct: 119 NDYYQCLSLL 128
>2KXP-C nrPDB
Length = 118
Score = 67.8 bits (164), Expect = 2e-11, Method: Composition-based stats.
Identities = 24/97 (24%), Positives = 38/97 (39%), Gaps = 6/97 (6%)
Query: 46 DSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPEL 105
D + A K DL +K + + D + G LH AA LE L+ ++
Sbjct: 3 DKEFMWALKNGDLDEVKDYVA-KGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADI 61
Query: 106 AKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGAS 142
T L AV +++ V+ LL++GA
Sbjct: 62 NAPDKHH-----ITPLLSAVYEGHVSCVKLLLSKGAD 93
Score = 66.7 bits (161), Expect = 3e-11, Method: Composition-based stats.
Identities = 25/120 (20%), Positives = 40/120 (33%), Gaps = 18/120 (15%)
Query: 83 LHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGAS 142
A +L+ + ++ + G+ LH A L ++ LL +GA
Sbjct: 6 FMWALKNGDLDEVKDYVAKGEDVNRT-----LEGGRKPLHYAADCGQLEILEFLLLKGAD 60
Query: 143 VSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHI 202
++A PL A G V+LL+ GAD + G T L
Sbjct: 61 INAPDKHHI-------------TPLLSAVYEGHVSCVKLLLSKGADKTVKGPDGLTALEA 107
Score = 60.9 bits (146), Expect = 2e-09, Method: Composition-based stats.
Identities = 34/141 (24%), Positives = 54/141 (38%), Gaps = 28/141 (19%)
Query: 121 LHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVR 180
A+ N +L+ V+ +A+G V+ + G PL +AA G EI+
Sbjct: 6 FMWALKNGDLDEVKDYVAKGEDVN-------------RTLEGGRKPLHYAADCGQLEILE 52
Query: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQG 240
L+ GADI A D T L + + + + LLLS + V G
Sbjct: 53 FLLLKGADINAPDKHHITPLLSAVYEGHVSCV----KLLLSKGAD-------KTVKGPDG 101
Query: 241 LTPFKLAGVEGNTVMFQHLMQ 261
LT + + + L+Q
Sbjct: 102 LTALEATDNQA----IKALLQ 118
Score = 48.2 bits (113), Expect = 1e-05, Method: Composition-based stats.
Identities = 22/115 (19%), Positives = 38/115 (33%), Gaps = 12/115 (10%)
Query: 168 SFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSD 227
+A G + V+ + G D+ G LH ++ LL +
Sbjct: 7 MWALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQ----LEILEFLLLKGADIN 62
Query: 228 HLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTE 282
P+ +TP A EG+ + L+ K + GP T + T+
Sbjct: 63 A-------PDKHHITPLLSAVYEGHVSCVKLLLSKGAD-KTVKGPDGLTALEATD 109
Score = 28.9 bits (63), Expect = 7.9, Method: Composition-based stats.
Identities = 14/37 (37%), Positives = 19/37 (51%), Gaps = 1/37 (2%)
Query: 47 SPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETAL 83
+PLL A E + LLL++ D +G G TAL
Sbjct: 70 TPLLSAVYEGHVS-CVKLLLSKGADKTVKGPDGLTAL 105
>3T9K-A nrPDB
Length = 390
Score = 67.0 bits (162), Expect = 3e-11, Method: Composition-based stats.
Identities = 25/117 (21%), Positives = 41/117 (35%), Gaps = 16/117 (13%)
Query: 99 MEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHN 158
+ ++ + T L A +L LL GA+V+ +
Sbjct: 220 LAHGADVNWVNGGQDNA---TPLIQATAANSLLACEFLLQNGANVNQADSA--------- 267
Query: 159 LIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQM 215
G PL A +G + L ++ GAD+ A+DS G L I + N +
Sbjct: 268 ----GRGPLHHATILGHTGLACLFLKRGADLGARDSEGRDPLTIAMETANADIVTLL 320
Score = 65.1 bits (157), Expect = 1e-10, Method: Composition-based stats.
Identities = 30/143 (20%), Positives = 45/143 (31%), Gaps = 23/143 (16%)
Query: 137 LARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLG 196
LA GA V+ G PL A S L+++GA++ DS G
Sbjct: 220 LAHGADVNWVNGGQD-----------NATPLIQATAANSLLACEFLLQNGANVNQADSAG 268
Query: 197 NTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMF 256
LH + + AC L L + +G P +A N +
Sbjct: 269 RGPLHHATILGHTGLAC----LFLKRGADLGA-------RDSEGRDPLTIAMETANADIV 317
Query: 257 QHL-MQKRKHVQWTCGPLTSTLY 278
L + K + + G Y
Sbjct: 318 TLLRLAKMREAEAAQGQAGDETY 340
Score = 60.1 bits (144), Expect = 3e-09, Method: Composition-based stats.
Identities = 26/102 (25%), Positives = 42/102 (41%), Gaps = 6/102 (5%)
Query: 35 RVNMLQQERIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEA 94
VN + + +PL+QA N L + LL N + Q + G LH A + +
Sbjct: 225 DVNWVNGGQDNATPLIQATAANSLLACEFLLQN-GANVNQADSAGRGPLHHATILGHTGL 283
Query: 95 ATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRAL 136
A L ++ +L G+ L IA+ N ++V L
Sbjct: 284 ACLFLKRGADL-----GARDSEGRDPLTIAMETANADIVTLL 320
>5D68-A nrPDB
Length = 486
Score = 65.9 bits (159), Expect = 6e-11, Method: Composition-based stats.
Identities = 34/165 (20%), Positives = 57/165 (34%), Gaps = 24/165 (14%)
Query: 25 GEQDWEQYRDRVNMLQQER-IRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETAL 83
++ W++ V ++ + + D PL ++A E D LL LL + Q + +
Sbjct: 17 KQEKWQRSMSSVTEDKERQWVDDFPLHRSACEGDSELLSRLLS-ERFSVNQLDSDHWAPI 75
Query: 84 HVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQ--TALHIAVMNQNLNLVRALLARGA 141
H A Y +EA +L+E GQ + LH A + +V+ LL
Sbjct: 76 HYACWYGKVEATRILLEKG------KCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNH-- 127
Query: 142 SVSARATGAAFRRSPHNLIYYGEHPLSFAACVGS--EEIVRLLIE 184
H G PL+ E L++
Sbjct: 128 ----------PETDRHITDQQGRSPLNICEENKQNNWEEAAKLLK 162
Score = 60.9 bits (146), Expect = 2e-09, Method: Composition-based stats.
Identities = 29/129 (22%), Positives = 46/129 (35%), Gaps = 18/129 (13%)
Query: 82 ALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGA 141
LH +A + E + L+ + + + +H A + R LL +G
Sbjct: 41 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWA-----PIHYACWYGKVEATRILLEKGK 95
Query: 142 SVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHG-ADIRAQDSLGNTVL 200
+P+ L PL FAA G EIV++L+ H D D G + L
Sbjct: 96 C------------NPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPL 143
Query: 201 HILILQPNK 209
+I
Sbjct: 144 NICEENKQN 152
Score = 43.6 bits (101), Expect = 4e-04, Method: Composition-based stats.
Identities = 24/143 (16%), Positives = 49/143 (34%), Gaps = 13/143 (9%)
Query: 166 PLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEH 225
PL +AC G E++ L+ + DS +H + +L
Sbjct: 41 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYAC-----WYGKVEATRILLEKGK 95
Query: 226 SDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQK---RKHVQWTCGPLTSTLYDLTE 282
+ + N Q +P A G+ + Q L+ +H+ G + + +
Sbjct: 96 CNPN-----LLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENK 150
Query: 283 IDSWGEELSFLELVVSSKKREAR 305
++W E L+ ++ + R
Sbjct: 151 QNNWEEAAKLLKEAINKPYEKVR 173
>3UI2-A nrPDB
Length = 244
Score = 65.9 bits (159), Expect = 6e-11, Method: Composition-based stats.
Identities = 29/103 (28%), Positives = 42/103 (40%), Gaps = 6/103 (5%)
Query: 45 RDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPE 104
++P AA++ D + L LL + D G TAL A + + LL EA +
Sbjct: 45 YETPWWTAARKADEQALSQLL--EDRDVDAVDENGRTALLFVAGLGSDKCVRLLAEAGAD 102
Query: 105 LAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARA 147
L G TALH+A +V AL+ GA +
Sbjct: 103 LDHRDMR----GGLTALHMAAGYVRPEVVEALVELGADIEVED 141
Score = 62.8 bits (151), Expect = 5e-10, Method: Composition-based stats.
Identities = 33/124 (26%), Positives = 45/124 (36%), Gaps = 18/124 (14%)
Query: 80 ETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLAR 139
ET AA + +A + L+E G+TAL + VR L
Sbjct: 46 ETPWWTAARKADEQALSQLLE------DRDVDAVDENGRTALLFVAGLGSDKCVRLLAEA 99
Query: 140 GASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTV 199
GA + R + G L AA E+V L+E GADI +D G T
Sbjct: 100 GADLDHRD------------MRGGLTALHMAAGYVRPEVVEALVELGADIEVEDERGLTA 147
Query: 200 LHIL 203
L +
Sbjct: 148 LELA 151
Score = 53.2 bits (126), Expect = 4e-07, Method: Composition-based stats.
Identities = 27/102 (26%), Positives = 37/102 (36%), Gaps = 7/102 (6%)
Query: 26 EQDWEQYRDRVNMLQQERIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVG-ETALH 84
EQ Q + ++ + + LL A LL D R G TALH
Sbjct: 58 EQALSQLLEDRDVDAVDENGRTALLFVAGLG-SDKCVRLLAEAGADLDHRDMRGGLTALH 116
Query: 85 VAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVM 126
+AA Y E L+E ++ E G TAL +A
Sbjct: 117 MAAGYVRPEVVEALVELGADI-----EVEDERGLTALELARE 153
Score = 40.5 bits (93), Expect = 0.003, Method: Composition-based stats.
Identities = 22/104 (21%), Positives = 35/104 (33%), Gaps = 11/104 (10%)
Query: 164 EHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD 223
E P AA E+ + L+E D+ A D G T L + + LL
Sbjct: 46 ETPWWTAARKADEQALSQLLEDR-DVDAVDENGRTALLFVAGLGSDKCV----RLLAEAG 100
Query: 224 EHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQ 267
DH GLT +A + + L++ ++
Sbjct: 101 ADLDHRDM------RGGLTALHMAAGYVRPEVVEALVELGADIE 138
>3EHQ-A nrPDB
Length = 222
Score = 65.5 bits (158), Expect = 8e-11, Method: Composition-based stats.
Identities = 33/108 (30%), Positives = 50/108 (46%), Gaps = 7/108 (6%)
Query: 40 QQERIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLM 99
+Q D+PL +AAK +L L+ L N+ G TAL+ A + + +L
Sbjct: 68 EQAESIDNPLHEAAKRGNLSWLRECLDNR-VGVNGLDKAGSTALYWACHGGHKDIVEMLF 126
Query: 100 -EAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSAR 146
+ EL ++ L G TALH A ++V+ LLA+GA R
Sbjct: 127 TQPNIELNQQNKL-----GDTALHAAAWKGYADIVQLLLAKGARTDLR 169
Score = 61.3 bits (147), Expect = 2e-09, Method: Composition-based stats.
Identities = 24/133 (18%), Positives = 42/133 (31%), Gaps = 17/133 (12%)
Query: 82 ALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGA 141
LH AA NL ++ + G TAL+ A + ++V L +
Sbjct: 76 PLHEAAKRGNLSWLRECLDNRVGVNGLDKA-----GSTALYWACHGGHKDIVEMLFTQ-- 128
Query: 142 SVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLH 201
+ G+ L AA G +IV+LL+ GA ++
Sbjct: 129 ----------PNIELNQQNKLGDTALHAAAWKGYADIVQLLLAKGARTDLRNIEKKLAFD 178
Query: 202 ILILQPNKTFACQ 214
+ + +
Sbjct: 179 MATNAACASLLKK 191
Score = 48.2 bits (113), Expect = 1e-05, Method: Composition-based stats.
Identities = 20/102 (19%), Positives = 35/102 (34%), Gaps = 10/102 (9%)
Query: 166 PLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEH 225
PL AA G+ +R +++ + D G+T L+ +K ++
Sbjct: 76 PLHEAAKRGNLSWLRECLDNRVGVNGLDKAGSTALYWACHGGHKDIVEMLF--------- 126
Query: 226 SDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQ 267
+ L N G T A +G + Q L+ K
Sbjct: 127 TQPNIELNQ-QNKLGDTALHAAAWKGYADIVQLLLAKGARTD 167
>3DEO-A nrPDB
Length = 183
Score = 65.1 bits (157), Expect = 9e-11, Method: Composition-based stats.
Identities = 29/103 (28%), Positives = 42/103 (40%), Gaps = 6/103 (5%)
Query: 45 RDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPE 104
++P AA++ D + L LL + D G TAL A + + LL EA +
Sbjct: 44 YETPWWTAARKADEQALSQLL--EDRDVDAVDENGRTALLFVAGLGSDKCVRLLAEAGAD 101
Query: 105 LAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARA 147
L G TALH+A +V AL+ GA +
Sbjct: 102 LDHRDMR----GGLTALHMAAGYVRPEVVEALVELGADIEVED 140
Score = 62.4 bits (150), Expect = 7e-10, Method: Composition-based stats.
Identities = 33/124 (26%), Positives = 45/124 (36%), Gaps = 18/124 (14%)
Query: 80 ETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLAR 139
ET AA + +A + L+E G+TAL + VR L
Sbjct: 45 ETPWWTAARKADEQALSQLLE------DRDVDAVDENGRTALLFVAGLGSDKCVRLLAEA 98
Query: 140 GASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTV 199
GA + R + G L AA E+V L+E GADI +D G T
Sbjct: 99 GADLDHRD------------MRGGLTALHMAAGYVRPEVVEALVELGADIEVEDERGLTA 146
Query: 200 LHIL 203
L +
Sbjct: 147 LELA 150
Score = 52.8 bits (125), Expect = 5e-07, Method: Composition-based stats.
Identities = 27/102 (26%), Positives = 37/102 (36%), Gaps = 7/102 (6%)
Query: 26 EQDWEQYRDRVNMLQQERIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVG-ETALH 84
EQ Q + ++ + + LL A LL D R G TALH
Sbjct: 57 EQALSQLLEDRDVDAVDENGRTALLFVAGLG-SDKCVRLLAEAGADLDHRDMRGGLTALH 115
Query: 85 VAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVM 126
+AA Y E L+E ++ E G TAL +A
Sbjct: 116 MAAGYVRPEVVEALVELGADI-----EVEDERGLTALELARE 152
Score = 40.1 bits (92), Expect = 0.004, Method: Composition-based stats.
Identities = 22/104 (21%), Positives = 35/104 (33%), Gaps = 11/104 (10%)
Query: 164 EHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD 223
E P AA E+ + L+E D+ A D G T L + + LL
Sbjct: 45 ETPWWTAARKADEQALSQLLEDR-DVDAVDENGRTALLFVAGLGSDKCV----RLLAEAG 99
Query: 224 EHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQ 267
DH GLT +A + + L++ ++
Sbjct: 100 ADLDHRDM------RGGLTALHMAAGYVRPEVVEALVELGADIE 137
>1D9S-A nrPDB
Length = 136
Score = 59.7 bits (143), Expect = 5e-09, Method: Composition-based stats.
Identities = 29/143 (20%), Positives = 45/143 (31%), Gaps = 19/143 (13%)
Query: 46 DSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPEL 105
D+ L AA + ++ LL D G + V + + + A LL+ E
Sbjct: 13 DAGLATAAARGQVETVRQLLEA-GADPNALNRFGRRPIQV-MMMGSAQVAELLLLHGAE- 69
Query: 106 AKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEH 165
P +P +H A L+ + L GA +G
Sbjct: 70 ---PNCADPATLTRPVHDAAREGFLDTLVVLHRAGA-------------RLDVCDAWGRL 113
Query: 166 PLSFAACVGSEEIVRLLIEHGAD 188
P+ A G +I R L D
Sbjct: 114 PVDLAEEQGHRDIARYLHAATGD 136
Score = 58.2 bits (139), Expect = 1e-08, Method: Composition-based stats.
Identities = 26/141 (18%), Positives = 47/141 (33%), Gaps = 18/141 (12%)
Query: 72 FQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLN 131
G + L AA +E L+EA + G+ + + +M +
Sbjct: 5 IHMLGGSSDAGLATAAARGQVETVRQLLEAGADPNALNRF-----GRRPIQV-MMMGSAQ 58
Query: 132 LVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRA 191
+ LL GA + R P+ AA G + + +L GA +
Sbjct: 59 VAELLLLHGAEPNCADPATLTR------------PVHDAAREGFLDTLVVLHRAGARLDV 106
Query: 192 QDSLGNTVLHILILQPNKTFA 212
D+ G + + Q ++ A
Sbjct: 107 CDAWGRLPVDLAEEQGHRDIA 127
Score = 53.6 bits (127), Expect = 3e-07, Method: Composition-based stats.
Identities = 28/127 (22%), Positives = 43/127 (33%), Gaps = 12/127 (9%)
Query: 167 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHS 226
L+ AA G E VR L+E GAD A + G + ++++ Q+ LLL +
Sbjct: 16 LATAAARGQVETVRQLLEAGADPNALNRFGRRPIQVMMMGS-----AQVAELLLLHGAEP 70
Query: 227 DHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSW 286
+ L P A EG L + + DL E
Sbjct: 71 NCADPATLTR------PVHDAAREGFLDTLVVLHRAGARLDVC-DAWGRLPVDLAEEQGH 123
Query: 287 GEELSFL 293
+ +L
Sbjct: 124 RDIARYL 130
>6BWF-A nrPDB
Length = 954
Score = 57.4 bits (137), Expect = 2e-08, Method: Composition-based stats.
Identities = 29/157 (18%), Positives = 60/157 (38%), Gaps = 23/157 (14%)
Query: 456 FALVLGWCSVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFHITFQTE 515
++ + ++ F Q GP+ +MI KM+ ++ +MA+V+L F
Sbjct: 621 LNIIFWYVRLLDFLAVNQQAGPYVMMIGKMV-ANMFYIVVIMALVLLSFGVPRKAILY-- 677
Query: 516 DPNNLGEFSDYPTALFSTFELFLTIIDGPA--------NYSVDLP-------FMYCITYA 560
P+ +S +F + +I G LP ++ A
Sbjct: 678 -PHEEPSWSLAKDIVFHPY----WMIFGEVYAYEIDVCANDSTLPTICGPGTWLTPFLQA 732
Query: 561 AFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQV 597
+ + ++M+NL IA + + +V + +W+ Q
Sbjct: 733 VYLFVQYIIMVNLLIAFFNNVYLQVKAISNIVWKYQR 769
>6DJS-A nrPDB
Length = 676
Score = 56.6 bits (135), Expect = 3e-08, Method: Composition-based stats.
Identities = 28/159 (17%), Positives = 60/159 (37%), Gaps = 23/159 (14%)
Query: 46 DSPLLQAAKENDLRLLKILLL-NQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPE 104
+ L AA+ ++ +++ +L +++ + +G+ AL +A ++LE LL++
Sbjct: 45 EERFLDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKK--- 101
Query: 105 LAKEPALCEPFVGQTALHIAVMNQNLNLVRALLAR-----------GASVSARATGAAFR 153
+ A AL +A+ + +V A+L +
Sbjct: 102 --ENLARIGD-----ALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYA 154
Query: 154 RSPHNLIYYGE-HPLSFAACVGSEEIVRLLIEHGADIRA 191
+ + P+ AA E+V +L+ GA I
Sbjct: 155 YDEDGTRFSPDITPIILAAHCQKYEVVHMLLMKGARIER 193
Score = 49.3 bits (116), Expect = 6e-06, Method: Composition-based stats.
Identities = 35/193 (18%), Positives = 58/193 (30%), Gaps = 40/193 (20%)
Query: 83 LHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGAS 142
AA Y N+ ++E + L C ++GQ AL +AV N++L + LL +
Sbjct: 48 FLDAAEYGNIPVVRKMLEESKTLN---VNCVDYMGQNALQLAVGNEHLEVTELLLKK--- 101
Query: 143 VSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHI 202
NL G+ L A G IV ++ H
Sbjct: 102 --------------ENLARIGD-ALLLAISKGYVRIVEAILNHPG--------------- 131
Query: 203 LILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQK 262
+K L D+ + + +TP LA + L+ K
Sbjct: 132 --FAASKRLTLSPCEQELQDDDFYAYDED--GTRFSPDITPIILAAHCQKYEVVHMLLMK 187
Query: 263 RKHVQWTCGPLTS 275
++
Sbjct: 188 GARIERPHDYFCK 200
>4BSZ-B nrPDB
Length = 202
Score = 56.3 bits (134), Expect = 4e-08, Method: Composition-based stats.
Identities = 33/147 (22%), Positives = 54/147 (36%), Gaps = 23/147 (15%)
Query: 49 LLQAAKENDLRLLK----ILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLME---- 100
++ A+ DL LK L+ + + TALH+AA ++E ++E
Sbjct: 18 IILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETVSR 77
Query: 101 -AAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALL-ARGASVSARATGAAFRRSPHN 158
+ E K G TALH A +N L++V+ L A R
Sbjct: 78 ANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNK---------- 127
Query: 159 LIYYGEHPLSFAACVGSEEIVRLLIEH 185
+G + A G EE+ ++
Sbjct: 128 ---FGHDAIFEAENSGKEEVETYFLKK 151
Score = 55.9 bits (133), Expect = 7e-08, Method: Composition-based stats.
Identities = 28/155 (18%), Positives = 57/155 (36%), Gaps = 8/155 (5%)
Query: 69 SCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQ 128
+ + + + A +L++ + E TALH+A N
Sbjct: 4 GLHSEPLDQEDQDTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANG 63
Query: 129 NLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLI-EHGA 187
++ VR +L +VS + + + + G L +A+ G ++V+LL E+ A
Sbjct: 64 HIETVRYILE---TVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEA 120
Query: 188 DIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSY 222
D ++ G H I + + ++ L
Sbjct: 121 DPFIRNKFG----HDAIFEAENSGKEEVETYFLKK 151
Score = 42.0 bits (97), Expect = 0.001, Method: Composition-based stats.
Identities = 23/108 (21%), Positives = 36/108 (33%), Gaps = 20/108 (18%)
Query: 165 HPLSFAACVGSEEIVRLLIE-----HGAD-----IRAQDSLGNTVLHILILQPNKTFACQ 214
L AA G E VR ++E + A+ + + GNT LH L
Sbjct: 54 TALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVK- 112
Query: 215 MYNLLLSYDEHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQK 262
LL + +D + N G A G + + ++K
Sbjct: 113 ----LLCDEYEADP-----FIRNKFGHDAIFEAENSGKEEVETYFLKK 151
>5U0K-A nrPDB
Length = 141
Score = 53.6 bits (127), Expect = 3e-07, Method: Composition-based stats.
Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 5/88 (5%)
Query: 49 LLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKE 108
LL AA D+ L+ + D +Q+ TALHVAA ++E L+EA K
Sbjct: 29 LLFAAYSGDVSALRRF-ALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEA----CKV 83
Query: 109 PALCEPFVGQTALHIAVMNQNLNLVRAL 136
+ G L AV +L +V+ L
Sbjct: 84 NPFAKDRWGNIPLDDAVQFNHLEVVKLL 111
Score = 52.8 bits (125), Expect = 6e-07, Method: Composition-based stats.
Identities = 22/100 (22%), Positives = 41/100 (41%), Gaps = 17/100 (17%)
Query: 83 LHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGAS 142
L AA ++ A +A ++ ++ + +TALH+A ++ +V+ L+
Sbjct: 29 LLFAAYSGDVSALRRFALSAMDMEQK-----DYDSRTALHVAAAEGHIEVVKFLIEA-CK 82
Query: 143 VSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLL 182
V+ A +G PL A E+V+LL
Sbjct: 83 VNPFAKDR-----------WGNIPLDDAVQFNHLEVVKLL 111
Score = 46.6 bits (109), Expect = 4e-05, Method: Composition-based stats.
Identities = 22/88 (25%), Positives = 31/88 (35%), Gaps = 2/88 (2%)
Query: 132 LVRALLA-RGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEH-GADI 189
+V L A VSA A Y L AA G E+V+ LIE +
Sbjct: 26 VVNLLFAAYSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEACKVNP 85
Query: 190 RAQDSLGNTVLHILILQPNKTFACQMYN 217
A+D GN L + + + +
Sbjct: 86 FAKDRWGNIPLDDAVQFNHLEVVKLLQD 113
Score = 45.1 bits (105), Expect = 1e-04, Method: Composition-based stats.
Identities = 15/63 (23%), Positives = 29/63 (46%)
Query: 36 VNMLQQERIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAA 95
++M Q++ + L AA E + ++K L+ + + G L A +++LE
Sbjct: 49 MDMEQKDYDSRTALHVAAAEGHIEVVKFLIEACKVNPFAKDRWGNIPLDDAVQFNHLEVV 108
Query: 96 TLL 98
LL
Sbjct: 109 KLL 111
>6BPQ-A nrPDB
Length = 950
Score = 52.4 bits (124), Expect = 6e-07, Method: Composition-based stats.
Identities = 41/236 (17%), Positives = 85/236 (36%), Gaps = 33/236 (13%)
Query: 389 ELVTVTGAVIILLLEIPDIFRVGASRYFGQTILGGPFHVIIITYASLVLLTMVMRLTNMN 448
E++ I+L E+ + G+ + + + + + +
Sbjct: 643 EIILYVLVFILLCDEVRQWYMNGSKYFSDLWNVMDTLAIFYFIAGIVFR----LHSDESS 698
Query: 449 GEVVPLSFAL--VLGWCSVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFAS 506
+ F L ++ +++ + LGP IM+Q+M+ D+ F +L AV ++ F
Sbjct: 699 WYSGRVIFCLDYIVFTLRLIHIFTVSRNLGPKIIMLQRMMI-DVFFFLFLFAVWMVAFGV 757
Query: 507 A------------------------FHITFQTEDPNNLGEFSDYPTALFSTFELFLTIID 542
A + Q D + G ++ FS E ++
Sbjct: 758 ARQGILRKNEHRWEWIFRSVIYEPYLAMFGQYPDDID-GTTYNFDHCTFSGNESKPLCVE 816
Query: 543 GPANYSVDLP-FMYCITYAAFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQV 597
AN P ++ + + +L++NL +AM G T V + D++W+ Q
Sbjct: 817 LDANNQPRFPEWITIPLVCIYMLSTNILLVNLLVAMFGYTVGSVQENNDQVWKFQR 872
>1DCQ-A nrPDB
Length = 278
Score = 50.9 bits (120), Expect = 2e-06, Method: Composition-based stats.
Identities = 34/166 (20%), Positives = 55/166 (33%), Gaps = 29/166 (17%)
Query: 30 EQYRDRVNMLQQERIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAV--------GET 81
+Y +R ++ + L + R + LL + + ET
Sbjct: 112 AKYMERRYARKKHADTAAKLHSLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDET 171
Query: 82 ALHVAALY---DNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLA 138
ALH+A +L L++ + L K+ G TALH + N ++ LL
Sbjct: 172 ALHLAVRSVDRTSLHIVDFLVQNSGNLDKQTG-----KGSTALHYCCLTDNAECLKLLLR 226
Query: 139 RGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIE 184
AS+ GE PL A + E LL +
Sbjct: 227 GKASIEIANES-------------GETPLDIAKRLKHEHCEELLTQ 259
Score = 43.9 bits (102), Expect = 2e-04, Method: Composition-based stats.
Identities = 27/155 (17%), Positives = 50/155 (32%), Gaps = 33/155 (21%)
Query: 53 AKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAAT-LLMEAAPELAKEPAL 111
A++ L + R G + A D ++ + + E +
Sbjct: 120 ARKKHADTAAKLHSLCEA-VKTRDIFGL----LQAYADGVDLTEKIPLANGHEPDE---- 170
Query: 112 CEPFVGQTALHIAV---MNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLS 168
TALH+AV +L++V L+ ++ + G L
Sbjct: 171 -------TALHLAVRSVDRTSLHIVDFLVQNSGNLDKQTGK-------------GSTALH 210
Query: 169 FAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHIL 203
+ + E ++LL+ A I + G T L I
Sbjct: 211 YCCLTDNAECLKLLLRGKASIEIANESGETPLDIA 245
Score = 40.5 bits (93), Expect = 0.003, Method: Composition-based stats.
Identities = 27/136 (19%), Positives = 41/136 (30%), Gaps = 20/136 (14%)
Query: 121 LHIAVMN-QNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACV---GSE 176
LH + ++ L A V + E L A S
Sbjct: 131 LHSLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPD-----ETALHLAVRSVDRTSL 185
Query: 177 EIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVP 236
IV L+++ ++ Q G+T LH L N + LLL +
Sbjct: 186 HIVDFLVQNSGNLDKQTGKGSTALHYCCLTDN----AECLKLLLRGKASI-------EIA 234
Query: 237 NHQGLTPFKLAGVEGN 252
N G TP +A +
Sbjct: 235 NESGETPLDIAKRLKH 250
>5UQE-A nrPDB
Length = 520
Score = 50.5 bits (119), Expect = 3e-06, Method: Composition-based stats.
Identities = 24/91 (26%), Positives = 39/91 (42%), Gaps = 5/91 (5%)
Query: 49 LLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKE 108
LL AA D+ L+ + D +QR TALHVAA ++E L+E A ++
Sbjct: 421 LLFAAYTGDVSALRRF-ALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLE-ACKVNPF 478
Query: 109 PALCEPFVGQTALHIAVMNQNLNLVRALLAR 139
P T + A+ + ++ + L
Sbjct: 479 PK---DRWNNTPMDEALHFGHHDVFKILQEY 506
Score = 46.2 bits (108), Expect = 5e-05, Method: Composition-based stats.
Identities = 21/110 (19%), Positives = 43/110 (39%), Gaps = 17/110 (15%)
Query: 83 LHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGAS 142
L AA ++ A +A ++ + + +TALH+A ++ +V+ LL
Sbjct: 421 LLFAAYTGDVSALRRFALSAMDMEQR-----DYDSRTALHVAAAEGHVEVVKFLLEA-CK 474
Query: 143 VSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQ 192
V+ F + + P+ A G ++ ++L E+ Q
Sbjct: 475 VNP------FPKDR-----WNNTPMDEALHFGHHDVFKILQEYQVQYTPQ 513
Score = 45.1 bits (105), Expect = 1e-04, Method: Composition-based stats.
Identities = 19/96 (19%), Positives = 29/96 (30%), Gaps = 1/96 (1%)
Query: 135 ALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEH-GADIRAQD 193
A VSA A Y L AA G E+V+ L+E + +D
Sbjct: 422 LFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKD 481
Query: 194 SLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHL 229
NT + + + + + Y D
Sbjct: 482 RWNNTPMDEALHFGHHDVFKILQEYQVQYTPQGDSD 517
Score = 38.9 bits (89), Expect = 0.009, Method: Composition-based stats.
Identities = 13/65 (20%), Positives = 28/65 (43%)
Query: 36 VNMLQQERIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAA 95
++M Q++ + L AA E + ++K LL + + T + A + + +
Sbjct: 441 MDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVF 500
Query: 96 TLLME 100
+L E
Sbjct: 501 KILQE 505
Score = 32.4 bits (72), Expect = 0.67, Method: Composition-based stats.
Identities = 19/98 (19%), Positives = 33/98 (33%), Gaps = 12/98 (12%)
Query: 167 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD-EH 225
L FAA G +R D+ +D T LH+ + + ++ LL +
Sbjct: 421 LLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGH----VEVVKFLLEACKVN 476
Query: 226 SDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKR 263
TP A G+ +F+ L + +
Sbjct: 477 PFPKDRWN-------NTPMDEALHFGHHDVFKILQEYQ 507
>5U0J-A nrPDB
Length = 140
Score = 50.5 bits (119), Expect = 3e-06, Method: Composition-based stats.
Identities = 24/108 (22%), Positives = 42/108 (38%), Gaps = 5/108 (4%)
Query: 49 LLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKE 108
LL AA D+ L+ + D +QR TALHVAA ++E L+EA K
Sbjct: 28 LLFAAYTGDVSALRRF-ALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEA----CKV 82
Query: 109 PALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSP 156
+ T + A+ + ++ + L + + + +
Sbjct: 83 NPFPKDRWNNTPMDEALHFGHHDVFKILQEYQVQYTPQGDSDNGKENQ 130
Score = 45.9 bits (107), Expect = 6e-05, Method: Composition-based stats.
Identities = 21/110 (19%), Positives = 43/110 (39%), Gaps = 17/110 (15%)
Query: 83 LHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGAS 142
L AA ++ A +A ++ + + +TALH+A ++ +V+ LL
Sbjct: 28 LLFAAYTGDVSALRRFALSAMDMEQR-----DYDSRTALHVAAAEGHVEVVKFLLEA-CK 81
Query: 143 VSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQ 192
V+ F + + P+ A G ++ ++L E+ Q
Sbjct: 82 VNP------FPKDR-----WNNTPMDEALHFGHHDVFKILQEYQVQYTPQ 120
Score = 45.9 bits (107), Expect = 7e-05, Method: Composition-based stats.
Identities = 22/108 (20%), Positives = 33/108 (30%), Gaps = 1/108 (0%)
Query: 135 ALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEH-GADIRAQD 193
A VSA A Y L AA G E+V+ L+E + +D
Sbjct: 29 LFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKD 88
Query: 194 SLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQGL 241
NT + + + + + Y D E H+ L
Sbjct: 89 RWNNTPMDEALHFGHHDVFKILQEYQVQYTPQGDSDNGKENQTVHKNL 136
Score = 39.7 bits (91), Expect = 0.005, Method: Composition-based stats.
Identities = 15/84 (17%), Positives = 32/84 (38%)
Query: 36 VNMLQQERIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAA 95
++M Q++ + L AA E + ++K LL + + T + A + + +
Sbjct: 48 MDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVF 107
Query: 96 TLLMEAAPELAKEPALCEPFVGQT 119
+L E + + QT
Sbjct: 108 KILQEYQVQYTPQGDSDNGKENQT 131
Score = 33.9 bits (76), Expect = 0.24, Method: Composition-based stats.
Identities = 22/127 (17%), Positives = 39/127 (30%), Gaps = 23/127 (18%)
Query: 167 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD-EH 225
L FAA G +R D+ +D T LH+ + + ++ LL +
Sbjct: 28 LLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGH----VEVVKFLLEACKVN 83
Query: 226 SDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDS 285
TP A G+ +F+ L + + P + D+
Sbjct: 84 PFPKDRWN-------NTPMDEALHFGHHDVFKILQEYQV----QYTPQGDS-------DN 125
Query: 286 WGEELSF 292
E +
Sbjct: 126 GKENQTV 132
>2A5E-A nrPDB
Length = 156
Score = 50.1 bits (118), Expect = 3e-06, Method: Composition-based stats.
Identities = 24/130 (18%), Positives = 45/130 (34%), Gaps = 18/130 (13%)
Query: 83 LHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGAS 142
L AA +E L+EA + G+ + + +M + + LL GA
Sbjct: 16 LATAAARGRVEEVRALLEAGALPNAPNS-----YGRRPIQV-MMMGSARVAELLLLHGAE 69
Query: 143 VSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHI 202
+ R P+ AA G + + +L GA + +D+ G + +
Sbjct: 70 PNCADPATLTR------------PVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDL 117
Query: 203 LILQPNKTFA 212
++ A
Sbjct: 118 AEELGHRDVA 127
Score = 47.0 bits (110), Expect = 3e-05, Method: Composition-based stats.
Identities = 27/143 (18%), Positives = 46/143 (32%), Gaps = 12/143 (8%)
Query: 167 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHS 226
L+ AA G E VR L+E GA A +S G + ++++ ++ LLL +
Sbjct: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGS-----ARVAELLLLHGAEP 70
Query: 227 DHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSW 286
+ L P A EG L + + DL E
Sbjct: 71 NCADPATLTR------PVHDAAREGFLDTLVVLHRAGARLD-VRDAWGRLPVDLAEELGH 123
Query: 287 GEELSFLELVVSSKKREARQILE 309
+ +L + ++
Sbjct: 124 RDVARYLRAAAGGTRGSNHARID 146
Score = 35.5 bits (80), Expect = 0.097, Method: Composition-based stats.
Identities = 13/52 (25%), Positives = 20/52 (38%), Gaps = 1/52 (1%)
Query: 47 SPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLL 98
P+ AA+E L L +L R A G + +A + + A L
Sbjct: 80 RPVHDAAREGFLDTLVVL-HRAGARLDVRDAWGRLPVDLAEELGHRDVARYL 130
>5Z1W-A nrPDB
Length = 566
Score = 45.5 bits (106), Expect = 9e-05, Method: Composition-based stats.
Identities = 23/131 (17%), Positives = 57/131 (43%), Gaps = 6/131 (4%)
Query: 458 LVLGWCSVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFHITFQTEDP 517
L W + + + + + + + D++ F + +V +A ++ F T+
Sbjct: 383 LFFAWIKIFKYISFNKTMTQLSSTLARCA-KDILGFAIMFFIVFFAYAQLGYLLFGTQ-- 439
Query: 518 NNLGEFSDYPTALFSTFELFLTIIDGPANYSVDLPFMYCITYAAFAIIATLLMLNLFIAM 577
+ FS + +F+ F + L D A + + + + + + ++LN+F+A+
Sbjct: 440 --VENFSTFVKCIFTQFRIILGDFDYNAIDNAN-RILGPVYFVTYVFFVFFVLLNMFLAI 496
Query: 578 MGDTHWRVAQE 588
+ DT+ V +E
Sbjct: 497 INDTYSEVKEE 507
>3LVQ-E nrPDB
Length = 497
Score = 45.1 bits (105), Expect = 1e-04, Method: Composition-based stats.
Identities = 23/93 (24%), Positives = 38/93 (40%), Gaps = 16/93 (17%)
Query: 121 LHIAVMNQN---LNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEE 177
LH+AV N L LV ++ G + A+A G L +AA +
Sbjct: 175 LHLAVKVANQASLPLVDFIIQNGGHLDAKAAD-------------GNTALHYAALYNQPD 221
Query: 178 IVRLLIEHGADIRAQDSLGNTVLHILILQPNKT 210
++LL++ A + + G T L I + +K
Sbjct: 222 CLKLLLKGRALVGTVNEAGETALDIARKKHHKE 254
Score = 45.1 bits (105), Expect = 1e-04, Method: Composition-based stats.
Identities = 27/99 (27%), Positives = 37/99 (37%), Gaps = 7/99 (7%)
Query: 49 LLQAAK-ENDLRL-LKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELA 106
L A K N L L ++ + A G TALH AALY+ + LL++ +
Sbjct: 175 LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVG 234
Query: 107 KEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSA 145
G+TAL IA + L A A
Sbjct: 235 TVNEA-----GETALDIARKKHHKECEELLEQAQAGTFA 268
Score = 40.1 bits (92), Expect = 0.004, Method: Composition-based stats.
Identities = 24/106 (22%), Positives = 37/106 (34%), Gaps = 14/106 (13%)
Query: 164 EHPLSFA---ACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLL 220
E L A A S +V +I++G + A+ + GNT LH L LL
Sbjct: 172 ELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLK-----LL 226
Query: 221 SYDEHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHV 266
+L N G T +A + + + L Q +
Sbjct: 227 LKGR------ALVGTVNEAGETALDIARKKHHKECEELLEQAQAGT 266
>2B0O-E nrPDB
Length = 301
Score = 45.1 bits (105), Expect = 1e-04, Method: Composition-based stats.
Identities = 23/93 (24%), Positives = 38/93 (40%), Gaps = 16/93 (17%)
Query: 121 LHIAVMNQN---LNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEE 177
LH+AV N L LV ++ G + A+A G L +AA +
Sbjct: 194 LHLAVKVANQASLPLVDFIIQNGGHLDAKAAD-------------GNTALHYAALYNQPD 240
Query: 178 IVRLLIEHGADIRAQDSLGNTVLHILILQPNKT 210
++LL++ A + + G T L I + +K
Sbjct: 241 CLKLLLKGRALVGTVNEAGETALDIARKKHHKE 273
Score = 45.1 bits (105), Expect = 1e-04, Method: Composition-based stats.
Identities = 27/99 (27%), Positives = 37/99 (37%), Gaps = 7/99 (7%)
Query: 49 LLQAAK-ENDLRL-LKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELA 106
L A K N L L ++ + A G TALH AALY+ + LL++ +
Sbjct: 194 LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVG 253
Query: 107 KEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSA 145
G+TAL IA + L A A
Sbjct: 254 TVNEA-----GETALDIARKKHHKECEELLEQAQAGTFA 287
Score = 40.1 bits (92), Expect = 0.004, Method: Composition-based stats.
Identities = 24/106 (22%), Positives = 37/106 (34%), Gaps = 14/106 (13%)
Query: 164 EHPLSFA---ACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLL 220
E L A A S +V +I++G + A+ + GNT LH L LL
Sbjct: 191 ELVLHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLK-----LL 245
Query: 221 SYDEHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHV 266
+L N G T +A + + + L Q +
Sbjct: 246 LKGR------ALVGTVNEAGETALDIARKKHHKECEELLEQAQAGT 285
>6DU8-A nrPDB
Length = 805
Score = 44.7 bits (104), Expect = 1e-04, Method: Composition-based stats.
Identities = 23/131 (17%), Positives = 56/131 (42%), Gaps = 6/131 (4%)
Query: 458 LVLGWCSVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFHITFQTEDP 517
L W + + + + + + + D++ F + +V +A ++ F T+
Sbjct: 446 LFFAWIKIFKYISFNKTMTQLSSTLARCA-KDILGFAVMFFIVFFAYAQLGYLLFGTQ-- 502
Query: 518 NNLGEFSDYPTALFSTFELFLTIIDGPANYSVDLPFMYCITYAAFAIIATLLMLNLFIAM 577
+ FS + +F+ F + L D A + + + + + ++LN+F+A+
Sbjct: 503 --VENFSTFIKCIFTQFRIILGDFDYNAIDNAN-RILGPAYFVTYVFFVFFVLLNMFLAI 559
Query: 578 MGDTHWRVAQE 588
+ DT+ V +E
Sbjct: 560 INDTYSEVKEE 570
>5UIL-A nrPDB
Length = 405
Score = 42.4 bits (98), Expect = 8e-04, Method: Composition-based stats.
Identities = 22/100 (22%), Positives = 45/100 (45%), Gaps = 9/100 (9%)
Query: 116 VGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGS 175
G + + +A + N+ L++ L+++GA+++ R + +Y+ ++ L G
Sbjct: 310 YGWSPVIVAAYHGNIELIKWLVSKGANINDRN-----YKGTTVAMYFKDYML----KSGD 360
Query: 176 EEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQM 215
+++LI+ G D+ D TV L NK M
Sbjct: 361 YSGLKMLIDLGLDLTLTDYKDYTVFDYLEKSGNKNLLQYM 400
Score = 40.1 bits (92), Expect = 0.004, Method: Composition-based stats.
Identities = 27/137 (19%), Positives = 51/137 (37%), Gaps = 20/137 (14%)
Query: 124 AVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLI 183
A + + L+ RA F ++ YG P+ AA G+ E+++ L+
Sbjct: 285 ACKYSDSKYIAKLI--------RAKSILFEKN-----IYGWSPVIVAAYHGNIELIKWLV 331
Query: 184 EHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQGLTP 243
GA+I ++ G TV K+ +L+ + +++ T
Sbjct: 332 SKGANINDRNYKGTTVAMYFKDYMLKSGDYSGLKMLIDLGLDL-------TLTDYKDYTV 384
Query: 244 FKLAGVEGNTVMFQHLM 260
F GN + Q++M
Sbjct: 385 FDYLEKSGNKNLLQYMM 401
>5MKE-A nrPDB
Length = 968
Score = 41.2 bits (95), Expect = 0.002, Method: Composition-based stats.
Identities = 43/255 (16%), Positives = 91/255 (35%), Gaps = 37/255 (14%)
Query: 462 WCSVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFHITFQTEDPNNLG 521
W + F + + + + + DL F + ++ L +A ++ F T+ +
Sbjct: 570 WIKLFKFINFNRTMSQLSTTMSRCA-KDLFGFAIMFFIIFLAYAQLAYLVFGTQ----VD 624
Query: 522 EFSDYPTALFSTFELFLTIIDGPANYSVDLPFMYCITYAAFAIIATLLMLNLFIAMMGDT 581
+FS + +F+ F + L I+ + + I + F ++LN+F+A++ DT
Sbjct: 625 DFSTFQECIFTQFRIILGDINFAEIEEAN-RVLGPIYFTTFVFFMFFILLNMFLAIINDT 683
Query: 582 HWRVAQE----------RDELWR-----AQVVATTVMLERKMPRFLWPRSGICGYEYGLG 626
+ V + D + + + + L G ++
Sbjct: 684 YSEVKSDLAQQKAEMELSDLIRKGYHKALVKLKLKKNTVDDISESLRQGGGKLNFDELRQ 743
Query: 627 DRWFLRVENHHDQNPLRVLRYVEAFKCSDKEDGQEQLSEKRPSTV------ESGMLSRAS 680
D L+ + H D +EA +DG ++L+E + E L
Sbjct: 744 D---LKGKGHTDAE-------IEAIFTKYDQDGDQELTEHEHQQMRDDLEKEREDLDLDH 793
Query: 681 VAFQTPSLSRTTSQS 695
+ P SR+ +S
Sbjct: 794 SSLPRPMSSRSFPRS 808
>5EK0-A nrPDB
Length = 296
Score = 41.2 bits (95), Expect = 0.002, Method: Composition-based stats.
Identities = 36/207 (17%), Positives = 72/207 (34%), Gaps = 11/207 (5%)
Query: 389 ELVTVTGAVIILLLEIPDIFRVGASRYFGQTILGGPFHVIIITYASLVLLTMVMRLTNMN 448
E++ V I+L I I R+ R + P+ + + ++ M +
Sbjct: 60 EVLYWINVVFIILFTIEIILRIYVHR---ISFFKDPWSLFDFVVVIISIVGMFLADLIET 116
Query: 449 GEVVPLSFALV----LGWCSVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGF 504
V P F ++ +G + QM + +I + ++ LM + F
Sbjct: 117 YFVSPTLFRVIRLARIGRI-LRLVTAVPQMRKIVSALIS--VIPGMLSVIALMTLFFYIF 173
Query: 505 ASAFHITFQTEDPNNLGEFSDYPTALFSTFELFLTIIDGPANYSVDLPFMYCITYAAFAI 564
A F P G + LF L + P+ + + F
Sbjct: 174 AIMATQLFGERFPEWFGTLGESFYTLFQVMTLESWSMGIVRPLMEVYPYAWVF-FIPFIF 232
Query: 565 IATLLMLNLFIAMMGDTHWRVAQERDE 591
+ T +M+NL +A++ D + Q+ ++
Sbjct: 233 VVTFVMINLVVAIIVDAMAILNQKEEQ 259
>5T4D-A nrPDB
Length = 510
Score = 40.9 bits (94), Expect = 0.002, Method: Composition-based stats.
Identities = 24/127 (18%), Positives = 55/127 (43%), Gaps = 6/127 (4%)
Query: 462 WCSVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFHITFQTEDPNNLG 521
W + F + + + + + DL F + ++ L +A ++ F T+ +
Sbjct: 378 WIKLFKFINFNRTMSQLSTTMSRCA-KDLFGFAIMFFIIFLAYAQLAYLVFGTQ----VD 432
Query: 522 EFSDYPTALFSTFELFLTIIDGPANYSVDLPFMYCITYAAFAIIATLLMLNLFIAMMGDT 581
+FS + +F+ F + L I+ + + I + F ++LN+F+A++ DT
Sbjct: 433 DFSTFQECIFTQFRIILGDINFAEIEEAN-RVLGPIYFTTFVFFMFFILLNMFLAIINDT 491
Query: 582 HWRVAQE 588
+ V +
Sbjct: 492 YSEVKSD 498
>5WPT-A nrPDB
Length = 592
Score = 40.9 bits (94), Expect = 0.002, Method: Composition-based stats.
Identities = 45/246 (18%), Positives = 96/246 (39%), Gaps = 29/246 (11%)
Query: 370 QKLLQEAYVTHQD-NIRLVGELVTVTGAVI------------ILLLEIPDIF---RVGAS 413
Q+ + H D + RL+ ++V + + LL +F R G
Sbjct: 282 QECKHPSVSRHGDNSFRLLFDVVVILTCSLSFLLCARSLLRGFLLQNEFVVFMWRRRGRE 341
Query: 414 RYFGQTI-LGGPFHVIIITYASLVLLTMVMR-------LTNMNGEVVPLSFALVLGWCSV 465
+ + ++++++T L + VM+ L + + + L + +L W V
Sbjct: 342 ISLWERLEFVNGWYILLVTSDVLTISGTVMKIGIEAKNLASYDVCSILLGTSTLLVWVGV 401
Query: 466 MYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFHITF--QTEDPNNLGEF 523
+ + F I ++ +MRFC +AV+ LG+ I +L
Sbjct: 402 IRYLTFFHKYNIL-IATLRVALPSVMRFCCCVAVIYLGYCFCGWIVLGPYHVKFRSLSMV 460
Query: 524 SDYPTALFSTFELFLTIIDGPANY-SVDLPFMYCITYA-AFAIIATLLMLNLFIAMMGDT 581
S+ +L + ++F+T A L +++ Y +F + ++L+LFIA++
Sbjct: 461 SECLFSLINGDDMFVTFAAMQAQQGHSSLVWLFSQLYLYSFISLFIYMVLSLFIALITGA 520
Query: 582 HWRVAQ 587
+ +
Sbjct: 521 YDTIKH 526
>6E7Z-A nrPDB
Length = 580
Score = 38.5 bits (88), Expect = 0.009, Method: Composition-based stats.
Identities = 43/246 (17%), Positives = 95/246 (38%), Gaps = 29/246 (11%)
Query: 370 QKLLQEAYVTHQD-NIRLVGELVTVTGAVIILLLEIPDIFR---------------VGAS 413
Q+ + H D + RL+ ++V + + LL + R G
Sbjct: 282 QECKHPSVFQHGDNSFRLLFDVVVILTCSLSFLLCARSLLRGFLLQNEFVGFMWRQRGRV 341
Query: 414 RYFGQTI-LGGPFHVIIITYASLVLLTMVMR-------LTNMNGEVVPLSFALVLGWCSV 465
+ + ++++++T L + +M+ L + + + L + +L W V
Sbjct: 342 ISLWERLEFVNGWYILLVTSDVLTISGTIMKIGIEAKNLASYDVCSILLGTSTLLVWVGV 401
Query: 466 MYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFHITF--QTEDPNNLGEF 523
+ + F I ++ +MRFC +AV+ LG+ I +L
Sbjct: 402 IRYLTFFHNYNIL-IATLRVALPSVMRFCCCVAVIYLGYCFCGWIVLGPYHVKFRSLSMV 460
Query: 524 SDYPTALFSTFELFLTIIDGPANY-SVDLPFMYCITYA-AFAIIATLLMLNLFIAMMGDT 581
S+ +L + ++F+T A L +++ Y +F + ++L+LFIA++
Sbjct: 461 SECLFSLINGDDMFVTFAAMQAQQGRSSLVWLFSQLYLYSFISLFIYMVLSLFIALITGA 520
Query: 582 HWRVAQ 587
+ +
Sbjct: 521 YDTIKH 526
>4DXW-A nrPDB
Length = 229
Score = 38.5 bits (88), Expect = 0.010, Method: Composition-based stats.
Identities = 24/103 (23%), Positives = 44/103 (42%), Gaps = 9/103 (8%)
Query: 481 MIQKMIFGDLMRFCWLMAVVILGFASAFHITFQTEDPNNLGEFSDYPTALFSTFELF-LT 539
++++ F L+ F L +A+ I F +DP+ G+ LF L
Sbjct: 129 SVRRVFFVSLLLFIILYI-----YATMGAILFGNDDPSRWGDLGISLITLFQVLTLSSWE 183
Query: 540 IIDGPANYSVDLPFMYCITYAAFAIIATLLMLNLFIAMMGDTH 582
+ P ++Y + +F II ++ +LNL IA++ D
Sbjct: 184 TVMLPMQEIYWWSWVY---FFSFIIICSITILNLVIAILVDVV 223
>6D1W-A nrPDB
Length = 740
Score = 38.5 bits (88), Expect = 0.010, Method: Composition-based stats.
Identities = 24/127 (18%), Positives = 55/127 (43%), Gaps = 6/127 (4%)
Query: 462 WCSVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFHITFQTEDPNNLG 521
W + F + + + + + DL F + ++ L +A ++ F T+ +
Sbjct: 518 WIKLFKFINFNRTMSQLSTTMSRCA-KDLFGFAIMPFIIFLAYAQLAYLVFGTQ----VD 572
Query: 522 EFSDYPTALFSTFELFLTIIDGPANYSVDLPFMYCITYAAFAIIATLLMLNLFIAMMGDT 581
+FS + +F+ F + L I+ + + I + F ++LN+F+A++ DT
Sbjct: 573 DFSTFQECIFTQFRIILGDINFAEIEEAN-RVLGPIYFTTFVFFMFFILLNMFLAIINDT 631
Query: 582 HWRVAQE 588
+ V +
Sbjct: 632 YSEVKSD 638
>3RVY-A nrPDB
Length = 285
Score = 38.5 bits (88), Expect = 0.010, Method: Composition-based stats.
Identities = 34/199 (17%), Positives = 65/199 (32%), Gaps = 15/199 (7%)
Query: 379 THQDNIRLVGELVTVTGAVIILLLEIPDIFRVGASRYFGQTILGGPFHVIIITYASLVLL 438
T + ++ G T+ ++I + I I R+ R + P+ + ++ L+
Sbjct: 51 TSKTFMQSFGVYTTLFNQIVITIFTIEIILRIYVHR---ISFFKDPWSLFDFFVVAISLV 107
Query: 439 TMVMRLTNMNGEVVPLSFALVLGWCSVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMA 498
+ V F LV QM + +I + ++ LM
Sbjct: 108 PTSSGFEILRVLRVLRLFRLV---------TAVPQMRKIVSALIS--VIPGMLSVIALMT 156
Query: 499 VVILGFASAFHITFQTEDPNNLGEFSDYPTALFSTFELFLTIIDGPANYSVDLPFMYCIT 558
+ FA F P G + LF L + P+ +
Sbjct: 157 LFFYIFAIMATQLFGERFPEWFGTLGESFYTLFQVMTLESWSMGIVRPLMEVYPYAWVF- 215
Query: 559 YAAFAIIATLLMLNLFIAM 577
+ F + T +M+NL +A+
Sbjct: 216 FIPFIFVVTFVMINLVVAI 234
>6AYG-A nrPDB
Length = 558
Score = 37.4 bits (85), Expect = 0.020, Method: Composition-based stats.
Identities = 38/192 (19%), Positives = 77/192 (40%), Gaps = 23/192 (11%)
Query: 444 LTNMNGEVVPLSFALVLGWCSVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILG 503
LT+ + + L + +L W V+ + F + +Q +++RFC A++ LG
Sbjct: 372 LTSYDVCSILLGTSTMLVWLGVIRYLGFFAKYNLLILTLQAA-LPNVIRFCCCAAMIYLG 430
Query: 504 FASAFHITFQTEDPNNLGEFSDYPTALFSTFELFLTIIDGP--------ANYSVDLPFMY 555
+ I LG + D +L E ++I+G L +++
Sbjct: 431 YCFCGWIV--------LGPYHDKFRSLNMVSECLFSLINGDDMFATFAKMQQKSYLVWLF 482
Query: 556 CITYA-AFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVATTVMLERKMPRFLWP 614
Y +F + ++L+LFIA++ DT+ + Q + + + + T + + +P
Sbjct: 483 SRIYLYSFISLFIYMILSLFIALITDTYETIKQYQQDGFPETELRTFISECKDLP----- 537
Query: 615 RSGICGYEYGLG 626
SG E
Sbjct: 538 NSGKYRLEDDPP 549
>4XD0-A nrPDB
Length = 417
Score = 37.4 bits (85), Expect = 0.023, Method: Composition-based stats.
Identities = 19/99 (19%), Positives = 44/99 (44%), Gaps = 9/99 (9%)
Query: 117 GQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSE 176
G + + IA + N++++ L+++G +++ R + +Y+ ++ L G E
Sbjct: 324 GWSPIIIAAYHGNMDVIEWLVSKGVNINDRN-----YKGTTVAMYFKDYMLRSGNYTGLE 378
Query: 177 EIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQM 215
++ L G D+ +D+ G +V + N M
Sbjct: 379 NLINL----GLDLFLKDNEGLSVFDYMRKNKNIELFNFM 413
Score = 37.4 bits (85), Expect = 0.024, Method: Composition-based stats.
Identities = 21/101 (20%), Positives = 40/101 (39%), Gaps = 15/101 (14%)
Query: 163 GEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVL----HILILQPNKTFACQMYNL 218
G P+ AA G+ +++ L+ G +I ++ G TV ++ N T + NL
Sbjct: 324 GWSPIIIAAYHGNMDVIEWLVSKGVNINDRNYKGTTVAMYFKDYMLRSGNYTGLENLINL 383
Query: 219 LLSYDEHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHL 259
L + +++GL+ F N +F +
Sbjct: 384 GLDL-----------FLKDNEGLSVFDYMRKNKNIELFNFM 413
>6BWI-A nrPDB
Length = 977
Score = 35.5 bits (80), Expect = 0.089, Method: Composition-based stats.
Identities = 33/164 (20%), Positives = 58/164 (35%), Gaps = 40/164 (24%)
Query: 473 QMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFHITFQTEDPNNLGEFSDYPTALFS 532
+ LGP +++ KM D+ F + + V ++ + A + D SD+P+ L
Sbjct: 715 KQLGPKIVIVSKM-MKDVFFFLFFLGVWLVAYGVATEGLLRPRD-------SDFPSILRR 766
Query: 533 TF-ELFLTIIDGPANYSVDLPFM-------------------YCITYAAFA--------- 563
F +L I +D+ M + +A
Sbjct: 767 VFYRPYLQIFGQIPQEDMDVALMEHSNCSSEPGFWAHPPGAQAGTCVSQYANWLVVLLLV 826
Query: 564 ---IIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVATTVML 604
++A +L++NL IAM T +V D W+AQ
Sbjct: 827 IFLLVANILLVNLLIAMFSYTFGKVQGNSDLYWKAQRYRLIREF 870
>4GX0-A nrPDB
Length = 565
Score = 34.7 bits (78), Expect = 0.14, Method: Composition-based stats.
Identities = 11/81 (13%), Positives = 29/81 (35%)
Query: 491 MRFCWLMAVVILGFASAFHITFQTEDPNNLGEFSDYPTALFSTFELFLTIIDGPANYSVD 550
++ L +L A+ F+ + G + ++ T + T+ G + D
Sbjct: 17 LKVLLLYCAFLLVMLLAYASIFRYLMWHLEGRAYSFMAGIYWTITVMTTLGFGDITFESD 76
Query: 551 LPFMYCITYAAFAIIATLLML 571
+++ +I ++L
Sbjct: 77 AGYLFASIVTVSGVIFLDIIL 97
>6N4I-A nrPDB
Length = 288
Score = 34.7 bits (78), Expect = 0.17, Method: Composition-based stats.
Identities = 33/180 (18%), Positives = 64/180 (35%), Gaps = 10/180 (5%)
Query: 399 ILLLEIPDIFRVGASRYFGQTILGGPFHVIIITYASLVLLTMV-MRLTNMNGEVVPLSFA 457
++ I I + + P+ + + +V L++V + L ++ G V SF
Sbjct: 67 LVFTGIFAIEIILRIYVHRISFFKDPWS---LFDSLIVTLSLVELFLADVEGLSVLRSFR 123
Query: 458 LVLGWCSVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFHITFQTEDP 517
L+ + V QM + +I + ++ LM + FA F P
Sbjct: 124 LLRVFRLVTAVP---QMRKIVSALIS--VIPGMLSVIALMTLFFYIFAIMATQLFGERFP 178
Query: 518 NNLGEFSDYPTALFSTFELFLTIIDGPANYSVDLPFMYCITYAAFAIIATLLMLNLFIAM 577
G + LF L + P+ + + F + T +M+NL +A+
Sbjct: 179 EWFGTLGESFYTLFQVMTLESWSMGIVRPLMEVYPYAWVF-FIPFIFVVTFVMINLVVAI 237
>5E1J-A nrPDB
Length = 741
Score = 32.8 bits (73), Expect = 0.51, Method: Composition-based stats.
Identities = 25/104 (24%), Positives = 46/104 (44%), Gaps = 7/104 (6%)
Query: 486 IFGDLMRFCWLMAVVILGFASAFHI-TFQTEDPNN---LGEFSDYPTALFSTFELFL--- 538
IF L +C + V G +A + F+TE + L F+DYP + + F L +
Sbjct: 572 IFCVLCIYCSIGVQVFGGLVNAGNKKLFETELAEDDYLLFNFNDYPNGMVTLFNLLVMGN 631
Query: 539 TIIDGPANYSVDLPFMYCITYAAFAIIATLLMLNLFIAMMGDTH 582
+ + + + + +F +I LL+LNL +A + +
Sbjct: 632 WQVWMESYKDLTGTWWSITYFVSFYVITILLLLNLVVAFVLEAF 675
>2GBW-A nrPDB
Length = 454
Score = 31.6 bits (70), Expect = 1.1, Method: Composition-based stats.
Identities = 30/150 (20%), Positives = 50/150 (33%), Gaps = 23/150 (15%)
Query: 180 RLLIEHGAD------IRAQDSLGNTVLHILILQPN-KTFACQMYNLLLSYDEHSDHLQSL 232
++++ H +D I + GN + H N K F C + + D L
Sbjct: 62 KVILSHQSDGTFRAFINSCSHRGNQICHA--DSGNAKAFVCNYHGWVFGQDGSL-VDVPL 118
Query: 233 ELVPNHQGLTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSWGEELSF 292
E H L KLA ++ + P +L D GE +
Sbjct: 119 ESRCYHNSLDKQKLAAKSVRVETYK------GFIFGCHDPEAPSLEDYL-----GEFRYY 167
Query: 293 LELVVSSKKREARQILEQTPVKELVSFKWK 322
L+ + ++L P+K L+ WK
Sbjct: 168 LDTIWEGAG-GGMELLG-PPMKSLLQCNWK 195
>3G2F-A nrPDB
Length = 336
Score = 30.8 bits (68), Expect = 2.4, Method: Composition-based stats.
Identities = 23/142 (16%), Positives = 48/142 (33%), Gaps = 20/142 (14%)
Query: 34 DRVNMLQQERIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLE 93
+R N + ++ I PL++ + + ++ ++ R L V Y N
Sbjct: 48 NRQNFINEKNIYRVPLME-----HDNIARFIVGDERVTADGRMEY----LLVMEYYPNGS 98
Query: 94 AATLLMEAAPE-LAKEPALCEPFVGQTALHI----------AVMNQNLNLVRALLARGAS 142
L + ++ G LH A+ +++LN L+ +
Sbjct: 99 LCKYLSLHTSDWVSSCRLAHSVTRGLAYLHTELPRGDHYKPAISHRDLNSRNVLVKNDGT 158
Query: 143 VSARATGAAFRRSPHNLIYYGE 164
G + R + + L+ GE
Sbjct: 159 CVISDFGLSMRLTGNRLVRPGE 180
>2FT0-A nrPDB
Length = 235
Score = 30.1 bits (66), Expect = 3.3, Method: Composition-based stats.
Identities = 12/51 (23%), Positives = 20/51 (39%)
Query: 101 AAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAA 151
A EL + G+T L +A N ++ + GA+V + A
Sbjct: 184 AGAELMQTALNWAYARGKTTLRVATQMGNTAALKRYIQSGANVESTAYWLY 234
>3CO4-A nrPDB
Length = 312
Score = 30.1 bits (66), Expect = 3.3, Method: Composition-based stats.
Identities = 22/97 (22%), Positives = 40/97 (41%), Gaps = 7/97 (7%)
Query: 2 GACPPKAKGPWA-QLQKLLISWPVGEQDWEQYRDRVNMLQQER--IRDSPLLQAAKENDL 58
G K K W +WEQY D +N++ +R D P+ A+ ++ +
Sbjct: 132 GLYLAKEKNMLMTCAVNS--RWLNYGTEWEQYFDYINLMSYDRGAFTDKPVQHASYDDFV 189
Query: 59 RLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAA 95
+ LK N+ C + VG + + ++L+ A
Sbjct: 190 KDLK--YWNEQCRASKSKIVGGLPFYGYSWEESLQGA 224
>2N4X-A nrPDB
Length = 208
Score = 28.9 bits (63), Expect = 7.2, Method: Composition-based stats.
Identities = 16/86 (18%), Positives = 34/86 (39%), Gaps = 2/86 (2%)
Query: 487 FGDLMRFCWLMAVVILGFASAFHITFQTEDPNNLGEFS-DYPTALFSTFELFLTIIDGPA 545
FG L+ F WL A++ A T +E+P + + + + F++ +
Sbjct: 117 FGMLLAFLWLPAILPFA-GIAISQTLLSENPLVMLSYGLGMAVTIAAVFKMGEKFVKANF 175
Query: 546 NYSVDLPFMYCITYAAFAIIATLLML 571
+ + Y A+ + +L+L
Sbjct: 176 QLIRKVTGAIVLLYLAYFALTEVLLL 201
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
Posted date: Jan 3, 2023 9:05 PM
Number of letters in database: 10,336,785
Number of sequences in database: 36,641
Lambda K H
0.315 0.130 0.342
Lambda K H
0.267 0.0398 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,281,015
Number of Sequences: 36641
Number of extensions: 925654
Number of successful extensions: 4327
Number of sequences better than 10.0: 99
Number of HSP's better than 10.0 without gapping: 135
Number of HSP's successfully gapped in prelim test: 47
Number of HSP's that attempted gapping in prelim test: 2789
Number of HSP's gapped (non-prelim): 500
length of query: 730
length of database: 10,336,785
effective HSP length: 104
effective length of query: 626
effective length of database: 6,526,121
effective search space: 4085351746
effective search space used: 4085351746
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.1 bits)
S2: 63 (28.9 bits)