BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9XSJ0 (328 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4UF6-A nrPDB 675 0.0 3RII-A nrPDB 476 e-135 4IG7-A nrPDB 295 3e-80 4I6N-A nrPDB 256 8e-69 6CGA-A nrPDB 193 7e-50 6HGC-B nrPDB 184 6e-47 6ISU-A nrPDB 84 7e-17 4JKJ-A nrPDB 64 1e-10 2WDT-A nrPDB 62 3e-10 1CMX-A nrPDB 54 8e-08 3GDO-A nrPDB 33 0.12 3ZHS-A nrPDB 29 2.8 5A7V-A nrPDB 28 6.4 >4UF6-A nrPDB Length = 331 Score = 675 bits (1741), Expect = 0.0, Method: Compositional matrix adjust. Identities = 324/328 (98%), Positives = 327/328 (99%) Query: 1 MTGNAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQP 60 MTGNAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQP Sbjct: 4 MTGNAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQP 63 Query: 61 GEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQS 120 GEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQS Sbjct: 64 GEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQS 123 Query: 121 FDAAMKGLALSNSDVIRQVHNSFARQQMFEFDAKTAAKEEDAFHFVSYVPVNGRLYELDG 180 FDAAMKGLALSNSDVIRQVHNSFARQQMFEFD KT+AKEEDAFHFVSYVPVNGRLYELDG Sbjct: 124 FDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTKTSAKEEDAFHFVSYVPVNGRLYELDG 183 Query: 181 LREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQR 240 LREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQR Sbjct: 184 LREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQR 243 Query: 241 QLAEEPMDTDQGSNMLSAIQSEVAKNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELLK 300 QLAEEPMDTDQG++MLSAIQSEVAKNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELLK Sbjct: 244 QLAEEPMDTDQGNSMLSAIQSEVAKNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELLK 303 Query: 301 TLAEHQQLIPLVEKAKEKQNAKKAQETK 328 TLAEHQQLIPLVEKAKEKQNAKKAQETK Sbjct: 304 TLAEHQQLIPLVEKAKEKQNAKKAQETK 331 >3RII-A nrPDB Length = 233 Score = 476 bits (1224), Expect = e-135, Method: Compositional matrix adjust. Identities = 225/228 (98%), Positives = 226/228 (99%) Query: 1 MTGNAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQP 60 MTGNAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQP Sbjct: 6 MTGNAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQP 65 Query: 61 GEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQS 120 GEEPAGSVVQDSRLDTIFFAKQVINNA ATQAIVSVLLNCTHQDVHLGETLSEFKEFSQS Sbjct: 66 GEEPAGSVVQDSRLDTIFFAKQVINNASATQAIVSVLLNCTHQDVHLGETLSEFKEFSQS 125 Query: 121 FDAAMKGLALSNSDVIRQVHNSFARQQMFEFDAKTAAKEEDAFHFVSYVPVNGRLYELDG 180 FDAAMKGLALSNSDVIRQVHNSFARQQMFEFD KT+AKEEDAFHFVSYVPVNGRLYELDG Sbjct: 126 FDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTKTSAKEEDAFHFVSYVPVNGRLYELDG 185 Query: 181 LREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRK 228 LREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRK Sbjct: 186 LREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRK 233 >4IG7-A nrPDB Length = 343 Score = 295 bits (754), Expect = 3e-80, Method: Compositional matrix adjust. Identities = 148/306 (48%), Positives = 200/306 (65%), Gaps = 22/306 (7%) Query: 6 GEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQPGEEPA 65 G WCL+ESDPG+FTE+I GFGC G QVEE+ L+ E+ E LKP+HG IFLF+W E Sbjct: 38 GNWCLIESDPGIFTEMIHGFGCTGLQVEELVVLD-ESIEHLKPIHGFIFLFRWLKKE--M 94 Query: 66 GSVVQDS--RLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQSFDA 123 V DS ++F++QVI NACA+QA++++LLNC H DV LG TL EFK+F+ D+ Sbjct: 95 RKEVDDSPQTCTDVYFSQQVIQNACASQALINLLLNCDHPDVDLGPTLKEFKDFTYDLDS 154 Query: 124 AMKGLALSNSDVIRQVHNSFARQQMFEFDAKTAAKEEDAFHFVSYVPVNGRLYELDGLRE 183 A +GL L+NS+ IR VHNSF RQQ+FE D + EED FHFV+YVPVN +YELDGLR Sbjct: 155 ASRGLCLTNSEKIRAVHNSFGRQQLFEIDDQQKLDEEDVFHFVTYVPVNDGVYELDGLRA 214 Query: 184 GPIDLGACNQD-DWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQRQL 242 P+ LG D DW I+++I+ Y E E+RFNLMA++SD+K+ YE+++ + + Sbjct: 215 APLRLGTVASDGDWTEVAIKAIKEKIKNYGESEVRFNLMAVISDQKLKYEREMEKFAQ-- 272 Query: 243 AEEPMDTDQGSNMLSAIQSEVAKNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELLKTL 302 + +EV + LI E K +RY +E R +HNY+PFI+ELL+ L Sbjct: 273 --------------AGDSAEVDRLVALIAAEDAKRERYAMEAARHRHNYVPFIVELLRIL 318 Query: 303 AEHQQL 308 AE + L Sbjct: 319 AEEEVL 324 >4I6N-A nrPDB Length = 231 Score = 256 bits (655), Expect = 8e-69, Method: Compositional matrix adjust. Identities = 123/226 (54%), Positives = 159/226 (70%), Gaps = 6/226 (2%) Query: 6 GEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQPGEEPA 65 G WCL+ESDPG+FTE+I GFGC G QVEE+ L+ E+ E LKP+HG IFLF+W E Sbjct: 9 GNWCLIESDPGIFTEMIHGFGCTGLQVEELVVLD-ESIEHLKPIHGFIFLFRWLKKE--M 65 Query: 66 GSVVQDS--RLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQSFDA 123 V DS ++F++QVI NACA+QA++++LLNC H DV LG TL EFK+F+ D+ Sbjct: 66 RKEVDDSPQTCTDVYFSQQVIQNACASQALINLLLNCDHPDVDLGPTLKEFKDFTYDLDS 125 Query: 124 AMKGLALSNSDVIRQVHNSFARQQMFEFDAKTAAKEEDAFHFVSYVPVNGRLYELDGLRE 183 A +GL L+NS+ IR VHNSF RQQ+FE D + EED FHFV+YVPVN +YELDGLR Sbjct: 126 ASRGLCLTNSEKIRAVHNSFGRQQLFEIDDQQKLDEEDVFHFVTYVPVNDGVYELDGLRA 185 Query: 184 GPIDLGACNQD-DWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRK 228 P+ LG D DW I+++I+ Y E E+RFNLMA++SD+K Sbjct: 186 APLRLGTVASDGDWTEVAIKAIKEKIKNYGESEVRFNLMAVISDQK 231 >6CGA-A nrPDB Length = 365 Score = 193 bits (491), Expect = 7e-50, Method: Compositional matrix adjust. Identities = 126/364 (34%), Positives = 188/364 (51%), Gaps = 61/364 (16%) Query: 5 AGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPV---HGLIFLFKW--- 58 A W +ESDPG+FT L+K FGC QVEE++ L+ KP+ +G IFLF+W Sbjct: 4 ADGWLELESDPGLFTLLLKDFGCHDVQVEEVYDLQ-------KPIESPYGFIFLFRWIEE 56 Query: 59 -----QPGEEPAGSVVQDSR-LDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLS 112 + E A V+D + +IFFA+QV+ N+CAT A++SVLLNC ++ LG+TLS Sbjct: 57 RRARRKIVETTAEIFVKDEEAISSIFFAQQVVPNSCATHALLSVLLNCNENNLQLGDTLS 116 Query: 113 EFKEFSQSFDAAMKGLALSNSDVIRQVHNSFARQQMFEFDAKTAAK------EEDAFHFV 166 K ++ KGLA+ N+ + HNS A Q +T A +AFHFV Sbjct: 117 RLKTHTKGMSPENKGLAIGNTPELACAHNSHAMPQARRRLERTGAGVSSCRFTGEAFHFV 176 Query: 167 SYVPVNGRLYELDGLREGPIDLGAC-NQDDWISAVRPVIEKRIQ-KYSEGEIRFNLMAIV 224 S+VP+NG+L+ELDGL+ P++ G + +DW R V+ +R+ E +IRFNLMA+V Sbjct: 177 SFVPINGQLFELDGLKPYPMNHGGWEDSEDWTDKFRRVMAERLGIATGEQDIRFNLMAVV 236 Query: 225 SDRKMIYEQKI-----------AELQRQL-AEEPMDTDQGSN------------------ 254 DR++ K+ LQ+ L A+E ++ G + Sbjct: 237 PDRRIAITHKLKMLRTNQAIVSGTLQKLLKADEQGESGNGDSQRPDTPTTLLEPSAFTAR 296 Query: 255 ----MLSAIQSEVAKNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELLKTLAEHQQLIP 310 +L + +E+A N+ + +E + +K++ RR HNY FI L LA L Sbjct: 297 DLQSLLKNLDTEIAINEQHLADENDRRHMFKVDASRRTHNYDKFICTFLSMLAHQGVLGE 356 Query: 311 LVEK 314 LV + Sbjct: 357 LVSQ 360 >6HGC-B nrPDB Length = 310 Score = 184 bits (466), Expect = 6e-47, Method: Compositional matrix adjust. Identities = 113/316 (35%), Positives = 174/316 (55%), Gaps = 40/316 (12%) Query: 5 AGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPV---HGLIFLFKW--- 58 A W +ESDPG+FT L+K FGC QVEE++ L+ KP+ +G IFLF+W Sbjct: 1 ADGWLELESDPGLFTLLLKDFGCHDVQVEEVYDLQ-------KPIESPYGFIFLFRWIEE 53 Query: 59 -----QPGEEPAGSVVQDSR-LDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLS 112 + E A V+D + +IFFA+QV+ N+CAT A++SVLLNC ++ LG+TLS Sbjct: 54 RRARRKIVETTAEIFVKDEEAISSIFFAQQVVPNSCATHALLSVLLNCNENNLQLGDTLS 113 Query: 113 EFKEFSQSFDAAMKGLALSNSDVIRQVHNSFARQQMFEFDAKTAAK------EEDAFHFV 166 K ++ KGLA+ N+ + HNS A Q +T A +AFHFV Sbjct: 114 RLKTHTKGMSPENKGLAIGNTPELACAHNSHAMPQARRRLERTGAGVSSCRFTGEAFHFV 173 Query: 167 SYVPVNGRLYELDGLREGPIDLGAC-NQDDWISAVRPVIEKRIQ-KYSEGEIRFNLMAIV 224 S+VP+NG+L+ELDGL+ P++ G + +DW R V+ +R+ E +IRFNLMA+V Sbjct: 174 SFVPINGQLFELDGLKPYPMNHGGWEDSEDWTDKFRRVMAERLGIATGEQDIRFNLMAVV 233 Query: 225 SDRKMIYEQKIAELQRQLA------EEPMDTDQGS-------NMLSAIQSEVAKNQMLIE 271 DR++ K+ L+ A ++ + GS ++L + +E+A N+ + Sbjct: 234 PDRRIAITHKLKMLRTNQAIVSGTLQKLLKAGSGSGSARDLQSLLKNLDTEIAINEQHLA 293 Query: 272 EEVQKLKRYKIENIRR 287 +E + +K++ RR Sbjct: 294 DENDRRHMFKVDASRR 309 >6ISU-A nrPDB Length = 230 Score = 84.3 bits (207), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 66/228 (28%), Positives = 111/228 (48%), Gaps = 18/228 (7%) Query: 8 WCLMESDPGVFTELIKGFGCR-GAQVEEIWSLEPENFEKL-KPVHGLIFLF----KWQ-- 59 W +E++P V + +K G Q +++ ++PE + +PV ++ LF K++ Sbjct: 6 WLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMDPELLSMVPRPVCAVLLLFPITEKYEVF 65 Query: 60 --PGEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHL--GETLSEFK 115 EE S QD +++F KQ I+NAC T ++ + N +H G TL +F Sbjct: 66 RTEEEEKIKSQGQDVT-SSVYFMKQTISNACGTIGLIHAIAN-NKDKMHFESGSTLKKFL 123 Query: 116 EFSQSFDAAMKGLALSNSDVIRQVHNSFARQQMFEFDAKTAAKEEDAFHFVSYVPVNGRL 175 E S S + L N D IR H + A + E + E+ HF++ V V+G L Sbjct: 124 EESVSMSPEERARYLENYDAIRVTHETSAHEGQTE---APSIDEKVDLHFIALVHVDGHL 180 Query: 176 YELDGLREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAI 223 YELDG + PI+ G + + + V +K +++ E+RFN +A+ Sbjct: 181 YELDGRKPFPINHGETSDETLLEDAIEVCKKFMER-DPDELRFNAIAL 227 >4JKJ-A nrPDB Length = 228 Score = 63.5 bits (153), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 55/228 (24%), Positives = 102/228 (44%), Gaps = 27/228 (11%) Query: 11 MESDPGVFTELIKGFGCRGA-QVEEIWSLEPENFEKL-KPVHGLIFLF---------KWQ 59 ME +P + +++ G G + ++ LE E+ + P L+ LF + + Sbjct: 11 MEINPEMLNKVLYRLGVAGQWRFVDVLGLEEESLGSVPAPACALLLLFPLTAQHENFRKK 70 Query: 60 PGEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQD---VHLGETLSEFKE 116 EE G V ++F KQ I N+C T ++ + N +QD G L +F Sbjct: 71 QIEELKGQEVSPK----VYFMKQTIGNSCGTIGLIHAVAN--NQDKLGFEDGSVLKQFLS 124 Query: 117 FSQSFDAAMKGLALSNSDVIRQVHNSFARQQMFEFDAKTAAKEEDAFHFVSYVPVNGRLY 176 ++ + ++ I+ H++ A++ D K FHF+ + V+G LY Sbjct: 125 ETEKMSPEDRAKCFEKNEAIQAAHDAVAQEGQCRVDDKVN------FHFILFNNVDGHLY 178 Query: 177 ELDGLREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAIV 224 ELDG P++ GA ++D + V + ++ +GE+RF+ +A+ Sbjct: 179 ELDGRMPFPVNHGASSEDTLLKDAAKVCREFTER-EQGEVRFSAVALC 225 >2WDT-A nrPDB Length = 232 Score = 62.0 bits (149), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 48/228 (21%), Positives = 98/228 (42%), Gaps = 21/228 (9%) Query: 8 WCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKL-KPVHGLIFLFKWQPGEEPAG 66 W +ES+P G + +I+ + + + +PV +IFL+ Sbjct: 7 WTPLESNPDSLYLYSCKLGQSKLKFVDIYGFNNDLLDMIPQPVQAVIFLYPVNDNIVSEN 66 Query: 67 SVVQDSRL----DTIFFAKQVINNACATQAIVSVLLNCTHQ-DVHLGETLSEFKEFSQSF 121 + L D ++F KQ I N+C T A++ + N ++ ++ L +F Sbjct: 67 NTNDKHNLKENFDNVWFIKQYIPNSCGTIALLHLYGNLRNKFELDKDSVLDDFFNKVNEM 126 Query: 122 DAAMKGLALSNSDVIRQVHNSFA-----RQQMFEFDAKTAAKEEDAFHFVSYVPVNGRLY 176 A +G L N+ I +H+ F R + + D HF+ +V + G++ Sbjct: 127 SAEKRGQELKNNKSIENLHHEFCGQVENRDDILDVDT----------HFIVFVQIEGKII 176 Query: 177 ELDGLREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAIV 224 ELDG ++ P N D+++ +I+ + + + ++RF+ +A++ Sbjct: 177 ELDGRKDHPTVHCFTNGDNFLYDTGKIIQDKFIEKCKDDLRFSALAVI 224 >1CMX-A nrPDB Length = 235 Score = 54.3 bits (129), Expect = 8e-08, Method: Compositional matrix adjust. Identities = 64/225 (28%), Positives = 97/225 (43%), Gaps = 21/225 (9%) Query: 1 MTGNAGEWCLMESDPGVFTELIKGFGCRGAQVE-EIWSL-EPENFEKL-KPVHGLIFLFK 57 M+G +ES+P VFT G + +I+SL EPE L +PV ++ LF Sbjct: 1 MSGENRAVVPIESNPEVFTNFAHKLGLKNEWAYFDIYSLTEPELLAFLPRPVKAIVLLFP 60 Query: 58 WQPGEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEF 117 + + S S D I+F KQ + NAC AI+ L N + G L F + Sbjct: 61 INEDRKSSTSQQITSSYDVIWF-KQSVKNACGLYAILHSLSN-NQSLLEPGSDLDNFLK- 117 Query: 118 SQS--------FDAAMKGLALSNSDVIRQVHNSFARQQMFEFDAKTAAKEEDAFHFVSYV 169 SQS FD + N VI++ +F+ Q A + H+++YV Sbjct: 118 SQSDTSSSKNRFDDVTTDQFVLN--VIKENVQTFSTGQ----SEAPEATADTNLHYITYV 171 Query: 170 PVNGRLYELDGLR-EGPIDLGACNQDDWISAVRPVIEKRIQKYSE 213 NG ++ELDG GP+ LG + + ++ R+ Y E Sbjct: 172 EENGGIFELDGRNLSGPLYLGKSDPTATDLIEQELVRVRVASYME 216 >3GDO-A nrPDB Length = 358 Score = 33.5 bits (75), Expect = 0.12, Method: Compositional matrix adjust. Identities = 26/106 (24%), Positives = 46/106 (43%), Gaps = 11/106 (10%) Query: 167 SYVPVNGRLYELDGLREGPIDLGACNQDDWISAVR-----------PVIEKRIQKYSEGE 215 S VP NG Y++ G I G Q+D + A R P ++ + Sbjct: 230 SIVPANGPRYQIHGKDSSFIKYGIDGQEDALRAGRKPEDDSWGADVPEFYGKLTTIRGSD 289 Query: 216 IRFNLMAIVSDRKMIYEQKIAELQRQLAEEPMDTDQGSNMLSAIQS 261 + + V+ + Y +KIAE R+ A P+ ++G N++ I++ Sbjct: 290 KKTETIPSVNGSYLTYYRKIAESIREGAALPVTAEEGINVIRIIEA 335 >3ZHS-A nrPDB Length = 868 Score = 29.3 bits (64), Expect = 2.8, Method: Compositional matrix adjust. Identities = 18/54 (33%), Positives = 28/54 (51%), Gaps = 6/54 (11%) Query: 200 VRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQRQLAEEPMDTDQGS 253 VRPV+EKR + EG I + +++ +I E K+ L Q DT +G+ Sbjct: 501 VRPVLEKRREMAYEGRIDWAFAELLALGSLIAEGKLVRLSGQ------DTQRGT 548 >5A7V-A nrPDB Length = 388 Score = 27.7 bits (60), Expect = 6.4, Method: Compositional matrix adjust. Identities = 20/81 (24%), Positives = 36/81 (44%), Gaps = 12/81 (14%) Query: 117 FSQSFDAAMKGLALSNSDVIRQVHNSFARQQMFEFDAKT----------AAKEEDAFHFV 166 F++++D L + ++ +V N +Q + + D K AA ED ++ Sbjct: 189 FAKAYDGKFFNLGCKSGSILTEVVN--GKQVIKKIDGKYFMYWGEEHVFAATSEDLVNWT 246 Query: 167 SYVPVNGRLYELDGLREGPID 187 YV +G L +L R+G D Sbjct: 247 PYVNTDGSLRKLFSPRDGHFD 267 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4UF6-A nrPDB 479 e-136 4IG7-A nrPDB 369 e-102 6CGA-A nrPDB 364 e-101 3RII-A nrPDB 342 1e-94 6HGC-B nrPDB 328 2e-90 4I6N-A nrPDB 297 4e-81 2WDT-A nrPDB 235 2e-62 6ISU-A nrPDB 233 8e-62 4JKJ-A nrPDB 215 2e-56 1CMX-A nrPDB 188 3e-48 Sequences not found previously or not previously below threshold: 5HAF-A nrPDB 29 2.6 CONVERGED! >4UF6-A nrPDB Length = 331 Score = 479 bits (1233), Expect = e-136, Method: Composition-based stats. Identities = 324/328 (98%), Positives = 327/328 (99%) Query: 1 MTGNAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQP 60 MTGNAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQP Sbjct: 4 MTGNAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQP 63 Query: 61 GEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQS 120 GEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQS Sbjct: 64 GEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQS 123 Query: 121 FDAAMKGLALSNSDVIRQVHNSFARQQMFEFDAKTAAKEEDAFHFVSYVPVNGRLYELDG 180 FDAAMKGLALSNSDVIRQVHNSFARQQMFEFD KT+AKEEDAFHFVSYVPVNGRLYELDG Sbjct: 124 FDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTKTSAKEEDAFHFVSYVPVNGRLYELDG 183 Query: 181 LREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQR 240 LREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQR Sbjct: 184 LREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQR 243 Query: 241 QLAEEPMDTDQGSNMLSAIQSEVAKNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELLK 300 QLAEEPMDTDQG++MLSAIQSEVAKNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELLK Sbjct: 244 QLAEEPMDTDQGNSMLSAIQSEVAKNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELLK 303 Query: 301 TLAEHQQLIPLVEKAKEKQNAKKAQETK 328 TLAEHQQLIPLVEKAKEKQNAKKAQETK Sbjct: 304 TLAEHQQLIPLVEKAKEKQNAKKAQETK 331 >4IG7-A nrPDB Length = 343 Score = 369 bits (947), Expect = e-102, Method: Composition-based stats. Identities = 146/317 (46%), Positives = 201/317 (63%), Gaps = 18/317 (5%) Query: 6 GEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQPGEEPA 65 G WCL+ESDPG+FTE+I GFGC G QVEE+ L+ E+ E LKP+HG IFLF+W E Sbjct: 38 GNWCLIESDPGIFTEMIHGFGCTGLQVEELVVLD-ESIEHLKPIHGFIFLFRWLKKEMRK 96 Query: 66 GSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQSFDAAM 125 ++F++QVI NACA+QA++++LLNC H DV LG TL EFK+F+ D+A Sbjct: 97 EVDDSPQTCTDVYFSQQVIQNACASQALINLLLNCDHPDVDLGPTLKEFKDFTYDLDSAS 156 Query: 126 KGLALSNSDVIRQVHNSFARQQMFEFDAKTAAKEEDAFHFVSYVPVNGRLYELDGLREGP 185 +GL L+NS+ IR VHNSF RQQ+FE D + EED FHFV+YVPVN +YELDGLR P Sbjct: 157 RGLCLTNSEKIRAVHNSFGRQQLFEIDDQQKLDEEDVFHFVTYVPVNDGVYELDGLRAAP 216 Query: 186 IDLGACNQD-DWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQRQLAE 244 + LG D DW I+++I+ Y E E+RFNLMA++SD+K+ YE+++ + + Sbjct: 217 LRLGTVASDGDWTEVAIKAIKEKIKNYGESEVRFNLMAVISDQKLKYEREMEKFAQ---- 272 Query: 245 EPMDTDQGSNMLSAIQSEVAKNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELLKTLAE 304 + +EV + LI E K +RY +E R +HNY+PFI+ELL+ LAE Sbjct: 273 ------------AGDSAEVDRLVALIAAEDAKRERYAMEAARHRHNYVPFIVELLRILAE 320 Query: 305 HQQLIPLVEKAKEKQNA 321 + L ++ + A Sbjct: 321 EEVLSRMLADVSDSNVA 337 >6CGA-A nrPDB Length = 365 Score = 364 bits (934), Expect = e-101, Method: Composition-based stats. Identities = 124/364 (34%), Positives = 186/364 (51%), Gaps = 61/364 (16%) Query: 5 AGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPV---HGLIFLFKW--- 58 A W +ESDPG+FT L+K FGC QVEE++ L+ KP+ +G IFLF+W Sbjct: 4 ADGWLELESDPGLFTLLLKDFGCHDVQVEEVYDLQ-------KPIESPYGFIFLFRWIEE 56 Query: 59 -----QPGEEPAGSVVQDSR-LDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLS 112 + E A V+D + +IFFA+QV+ N+CAT A++SVLLNC ++ LG+TLS Sbjct: 57 RRARRKIVETTAEIFVKDEEAISSIFFAQQVVPNSCATHALLSVLLNCNENNLQLGDTLS 116 Query: 113 EFKEFSQSFDAAMKGLALSNSDVIRQVHNSFARQQMFEFDAKTAAK------EEDAFHFV 166 K ++ KGLA+ N+ + HNS A Q +T A +AFHFV Sbjct: 117 RLKTHTKGMSPENKGLAIGNTPELACAHNSHAMPQARRRLERTGAGVSSCRFTGEAFHFV 176 Query: 167 SYVPVNGRLYELDGLREGPIDLGAC-NQDDWISAVRPVIEKRIQ-KYSEGEIRFNLMAIV 224 S+VP+NG+L+ELDGL+ P++ G + +DW R V+ +R+ E +IRFNLMA+V Sbjct: 177 SFVPINGQLFELDGLKPYPMNHGGWEDSEDWTDKFRRVMAERLGIATGEQDIRFNLMAVV 236 Query: 225 SDRKMIYEQKIAELQRQL------------AEEPMDTDQGS------------------- 253 DR++ K+ L+ A+E ++ G Sbjct: 237 PDRRIAITHKLKMLRTNQAIVSGTLQKLLKADEQGESGNGDSQRPDTPTTLLEPSAFTAR 296 Query: 254 ---NMLSAIQSEVAKNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELLKTLAEHQQLIP 310 ++L + +E+A N+ + +E + +K++ RR HNY FI L LA L Sbjct: 297 DLQSLLKNLDTEIAINEQHLADENDRRHMFKVDASRRTHNYDKFICTFLSMLAHQGVLGE 356 Query: 311 LVEK 314 LV + Sbjct: 357 LVSQ 360 >3RII-A nrPDB Length = 233 Score = 342 bits (877), Expect = 1e-94, Method: Composition-based stats. Identities = 225/228 (98%), Positives = 226/228 (99%) Query: 1 MTGNAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQP 60 MTGNAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQP Sbjct: 6 MTGNAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQP 65 Query: 61 GEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQS 120 GEEPAGSVVQDSRLDTIFFAKQVINNA ATQAIVSVLLNCTHQDVHLGETLSEFKEFSQS Sbjct: 66 GEEPAGSVVQDSRLDTIFFAKQVINNASATQAIVSVLLNCTHQDVHLGETLSEFKEFSQS 125 Query: 121 FDAAMKGLALSNSDVIRQVHNSFARQQMFEFDAKTAAKEEDAFHFVSYVPVNGRLYELDG 180 FDAAMKGLALSNSDVIRQVHNSFARQQMFEFD KT+AKEEDAFHFVSYVPVNGRLYELDG Sbjct: 126 FDAAMKGLALSNSDVIRQVHNSFARQQMFEFDTKTSAKEEDAFHFVSYVPVNGRLYELDG 185 Query: 181 LREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRK 228 LREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRK Sbjct: 186 LREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRK 233 >6HGC-B nrPDB Length = 310 Score = 328 bits (841), Expect = 2e-90, Method: Composition-based stats. Identities = 113/317 (35%), Positives = 174/317 (54%), Gaps = 40/317 (12%) Query: 5 AGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPV---HGLIFLFKW--- 58 A W +ESDPG+FT L+K FGC QVEE++ L+ KP+ +G IFLF+W Sbjct: 1 ADGWLELESDPGLFTLLLKDFGCHDVQVEEVYDLQ-------KPIESPYGFIFLFRWIEE 53 Query: 59 -----QPGEEPAGSVVQDSR-LDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLS 112 + E A V+D + +IFFA+QV+ N+CAT A++SVLLNC ++ LG+TLS Sbjct: 54 RRARRKIVETTAEIFVKDEEAISSIFFAQQVVPNSCATHALLSVLLNCNENNLQLGDTLS 113 Query: 113 EFKEFSQSFDAAMKGLALSNSDVIRQVHNSFARQQMFEFDAKTAAK------EEDAFHFV 166 K ++ KGLA+ N+ + HNS A Q +T A +AFHFV Sbjct: 114 RLKTHTKGMSPENKGLAIGNTPELACAHNSHAMPQARRRLERTGAGVSSCRFTGEAFHFV 173 Query: 167 SYVPVNGRLYELDGLREGPIDLGAC-NQDDWISAVRPVIEKRIQ-KYSEGEIRFNLMAIV 224 S+VP+NG+L+ELDGL+ P++ G + +DW R V+ +R+ E +IRFNLMA+V Sbjct: 174 SFVPINGQLFELDGLKPYPMNHGGWEDSEDWTDKFRRVMAERLGIATGEQDIRFNLMAVV 233 Query: 225 SDRKMIYEQKIAELQRQLA------EEPMDTDQGS-------NMLSAIQSEVAKNQMLIE 271 DR++ K+ L+ A ++ + GS ++L + +E+A N+ + Sbjct: 234 PDRRIAITHKLKMLRTNQAIVSGTLQKLLKAGSGSGSARDLQSLLKNLDTEIAINEQHLA 293 Query: 272 EEVQKLKRYKIENIRRK 288 +E + +K++ RR Sbjct: 294 DENDRRHMFKVDASRRT 310 >4I6N-A nrPDB Length = 231 Score = 297 bits (760), Expect = 4e-81, Method: Composition-based stats. Identities = 120/224 (53%), Positives = 156/224 (69%), Gaps = 2/224 (0%) Query: 6 GEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQPGEEPA 65 G WCL+ESDPG+FTE+I GFGC G QVEE+ L+ E+ E LKP+HG IFLF+W E Sbjct: 9 GNWCLIESDPGIFTEMIHGFGCTGLQVEELVVLD-ESIEHLKPIHGFIFLFRWLKKEMRK 67 Query: 66 GSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQSFDAAM 125 ++F++QVI NACA+QA++++LLNC H DV LG TL EFK+F+ D+A Sbjct: 68 EVDDSPQTCTDVYFSQQVIQNACASQALINLLLNCDHPDVDLGPTLKEFKDFTYDLDSAS 127 Query: 126 KGLALSNSDVIRQVHNSFARQQMFEFDAKTAAKEEDAFHFVSYVPVNGRLYELDGLREGP 185 +GL L+NS+ IR VHNSF RQQ+FE D + EED FHFV+YVPVN +YELDGLR P Sbjct: 128 RGLCLTNSEKIRAVHNSFGRQQLFEIDDQQKLDEEDVFHFVTYVPVNDGVYELDGLRAAP 187 Query: 186 IDLGACNQD-DWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDRK 228 + LG D DW I+++I+ Y E E+RFNLMA++SD+K Sbjct: 188 LRLGTVASDGDWTEVAIKAIKEKIKNYGESEVRFNLMAVISDQK 231 >2WDT-A nrPDB Length = 232 Score = 235 bits (600), Expect = 2e-62, Method: Composition-based stats. Identities = 48/230 (20%), Positives = 98/230 (42%), Gaps = 11/230 (4%) Query: 3 GNAGEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKL-KPVHGLIFLFKWQPG 61 W +ES+P G + +I+ + + + +PV +IFL+ Sbjct: 2 AKNDIWTPLESNPDSLYLYSCKLGQSKLKFVDIYGFNNDLLDMIPQPVQAVIFLYPVNDN 61 Query: 62 EEPAGSVVQDSRL----DTIFFAKQVINNACATQAIVSVLLNCTHQ-DVHLGETLSEFKE 116 + L D ++F KQ I N+C T A++ + N ++ ++ L +F Sbjct: 62 IVSENNTNDKHNLKENFDNVWFIKQYIPNSCGTIALLHLYGNLRNKFELDKDSVLDDFFN 121 Query: 117 FSQSFDAAMKGLALSNSDVIRQVHNSFARQQMFEFDAKTAAKEEDAFHFVSYVPVNGRLY 176 A +G L N+ I +H+ F Q+ D HF+ +V + G++ Sbjct: 122 KVNEMSAEKRGQELKNNKSIENLHHEFC-GQVENRDDILDVDT----HFIVFVQIEGKII 176 Query: 177 ELDGLREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAIVSD 226 ELDG ++ P N D+++ +I+ + + + ++RF+ +A++ + Sbjct: 177 ELDGRKDHPTVHCFTNGDNFLYDTGKIIQDKFIEKCKDDLRFSALAVIPN 226 >6ISU-A nrPDB Length = 230 Score = 233 bits (594), Expect = 8e-62, Method: Composition-based stats. Identities = 65/232 (28%), Positives = 108/232 (46%), Gaps = 18/232 (7%) Query: 4 NAGEWCLMESDPGVFTELIKGFGCR-GAQVEEIWSLEPENFEKL-KPVHGLIFLFKWQP- 60 W +E++P V + +K G Q +++ ++PE + +PV ++ LF Sbjct: 2 EGQRWLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMDPELLSMVPRPVCAVLLLFPITEK 61 Query: 61 -------GEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHL--GETL 111 EE S QD +++F KQ I+NAC T ++ + N +H G TL Sbjct: 62 YEVFRTEEEEKIKSQGQDVT-SSVYFMKQTISNACGTIGLIHAIAN-NKDKMHFESGSTL 119 Query: 112 SEFKEFSQSFDAAMKGLALSNSDVIRQVHNSFARQQMFEFDAKTAAKEEDAFHFVSYVPV 171 +F E S S + L N D IR H + A + E + E+ HF++ V V Sbjct: 120 KKFLEESVSMSPEERARYLENYDAIRVTHETSAHEGQTE---APSIDEKVDLHFIALVHV 176 Query: 172 NGRLYELDGLREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAI 223 +G LYELDG + PI+ G + + + V +K +++ E+RFN +A+ Sbjct: 177 DGHLYELDGRKPFPINHGETSDETLLEDAIEVCKKFMER-DPDELRFNAIAL 227 >4JKJ-A nrPDB Length = 228 Score = 215 bits (548), Expect = 2e-56, Method: Composition-based stats. Identities = 53/227 (23%), Positives = 99/227 (43%), Gaps = 23/227 (10%) Query: 10 LMESDPGVFTELIKGFGCRG-AQVEEIWSLEPENFEKL-KPVHGLIFLFK---------W 58 ME +P + +++ G G + ++ LE E+ + P L+ LF Sbjct: 10 PMEINPEMLNKVLYRLGVAGQWRFVDVLGLEEESLGSVPAPACALLLLFPLTAQHENFRK 69 Query: 59 QPGEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQD-VHLGETLSEFKEF 117 + EE G V ++F KQ I N+C T ++ + N + G L +F Sbjct: 70 KQIEELKGQEVSPK----VYFMKQTIGNSCGTIGLIHAVANNQDKLGFEDGSVLKQFLSE 125 Query: 118 SQSFDAAMKGLALSNSDVIRQVHNSFARQQMFEFDAKTAAKEEDAFHFVSYVPVNGRLYE 177 ++ + ++ I+ H++ A++ D K FHF+ + V+G LYE Sbjct: 126 TEKMSPEDRAKCFEKNEAIQAAHDAVAQEGQCRVDDKVN------FHFILFNNVDGHLYE 179 Query: 178 LDGLREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAIV 224 LDG P++ GA ++D + V + ++ +GE+RF+ +A+ Sbjct: 180 LDGRMPFPVNHGASSEDTLLKDAAKVCREFTER-EQGEVRFSAVALC 225 >1CMX-A nrPDB Length = 235 Score = 188 bits (477), Expect = 3e-48, Method: Composition-based stats. Identities = 62/242 (25%), Positives = 100/242 (41%), Gaps = 24/242 (9%) Query: 1 MTGNAGEWCLMESDPGVFTELIKGFGCRGAQVE-EIWSL-EPENFEKL-KPVHGLIFLFK 57 M+G +ES+P VFT G + +I+SL EPE L +PV ++ LF Sbjct: 1 MSGENRAVVPIESNPEVFTNFAHKLGLKNEWAYFDIYSLTEPELLAFLPRPVKAIVLLFP 60 Query: 58 WQPGEEPAGSVVQDSRLDTIFFAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEF 117 + + S S D I+F KQ + NAC AI+ L N + G L F + Sbjct: 61 INEDRKSSTSQQITSSYDVIWF-KQSVKNACGLYAILHSLSN-NQSLLEPGSDLDNFLKS 118 Query: 118 SQS-------FDAAMKGLALSNSDVIRQVHNSFARQQMFEFDAKTAAKEEDAFHFVSYVP 170 FD + N VI++ +F+ Q A + H+++YV Sbjct: 119 QSDTSSSKNRFDDVTTDQFVLN--VIKENVQTFSTGQ----SEAPEATADTNLHYITYVE 172 Query: 171 VNGRLYELDGLR-EGPIDLGACNQDDWISAVRPVIEKRIQKYS-----EGEIRFNLMAIV 224 NG ++ELDG GP+ LG + + ++ R+ Y E + F ++ + Sbjct: 173 ENGGIFELDGRNLSGPLYLGKSDPTATDLIEQELVRVRVASYMENANEEDVLNFAMLGLG 232 Query: 225 SD 226 + Sbjct: 233 PN 234 >5HAF-A nrPDB Length = 338 Score = 29.3 bits (64), Expect = 2.6, Method: Composition-based stats. Identities = 25/142 (17%), Positives = 49/142 (34%), Gaps = 23/142 (16%) Query: 19 TELIKGFGCRGAQVEEIWSLEPE-------NFEKLKPVHGLIFLFKWQPGEEPAGSVVQD 71 T+L++ G E++ + ++ + + LIF + E +++ Sbjct: 197 TQLLEKIAQSGLSHNEVFLVNTGDHWLLCLFYKLAEKIKCLIFNTYYDLNENTKQEIIEA 256 Query: 72 ------SRLDTIFFA----KQVINNACAT--QAIVSVLLNCTHQDVHLGETLSEFKEFSQ 119 S D + F + + N C + +L N D TL EF E Sbjct: 257 AKIAGISESDEVNFIEMNLQNNVPNGCGLFCYHTIQLLSNAGQND--PATTLREFAENFL 314 Query: 120 SFDAAMKGLALSNSDVIRQVHN 141 + + L N+ RQ++ Sbjct: 315 TLSVEEQALF--NTQTRRQIYE 334 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.313 0.128 0.315 Lambda K H 0.267 0.0384 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,505,232 Number of Sequences: 36641 Number of extensions: 355822 Number of successful extensions: 1140 Number of sequences better than 10.0: 15 Number of HSP's better than 10.0 without gapping: 25 Number of HSP's successfully gapped in prelim test: 21 Number of HSP's that attempted gapping in prelim test: 1058 Number of HSP's gapped (non-prelim): 47 length of query: 328 length of database: 10,336,785 effective HSP length: 97 effective length of query: 231 effective length of database: 6,782,608 effective search space: 1566782448 effective search space used: 1566782448 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.5 bits) S2: 59 (27.4 bits)