BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9WVL0 (216 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2CZ2-A nrPDB 444 e-125 1FW1-A nrPDB 384 e-107 1E6B-A nrPDB 197 4e-51 4IGJ-A nrPDB 186 5e-48 3LG6-A nrPDB 178 2e-45 3NIV-A nrPDB 171 3e-43 6JWK-A nrPDB 157 3e-39 2JL4-A nrPDB 151 2e-37 4PXO-A nrPDB 139 8e-34 4QQ7-A nrPDB 73 7e-14 3M3M-A nrPDB 67 8e-12 5F0G-A nrPDB 66 1e-11 4YH2-A nrPDB 65 2e-11 4J2F-A nrPDB 65 2e-11 3WD6-A nrPDB 65 3e-11 4PNG-A nrPDB 64 4e-11 1PN9-A nrPDB 64 5e-11 2VCV-A nrPDB 63 8e-11 4CHS-A nrPDB 62 1e-10 3UBL-A nrPDB 62 2e-10 2VO4-A nrPDB 62 2e-10 1VF1-A nrPDB 61 3e-10 5J5N-A nrPDB 61 4e-10 3VWX-A nrPDB 60 5e-10 1F3B-A nrPDB 60 6e-10 3QAG-A nrPDB 60 9e-10 3LFL-A nrPDB 60 9e-10 1JLV-A nrPDB 59 1e-09 5ECL-B nrPDB 59 1e-09 3I6A-A nrPDB 59 1e-09 3UAR-A nrPDB 59 2e-09 1PL2-A nrPDB 59 2e-09 2GDR-A nrPDB 59 2e-09 3MAK-A nrPDB 59 2e-09 1V2A-A nrPDB 57 6e-09 2VCT-A nrPDB 57 8e-09 4MK3-A nrPDB 57 8e-09 5ZWP-A nrPDB 57 9e-09 1GUL-A nrPDB 56 9e-09 1YQ1-A nrPDB 56 1e-08 5F06-A nrPDB 55 2e-08 3GH6-A nrPDB 55 3e-08 1GWC-A nrPDB 55 3e-08 1F2E-A nrPDB 54 7e-08 1EV4-A nrPDB 53 9e-08 6F05-A nrPDB 53 1e-07 3M8N-A nrPDB 52 1e-07 4PQI-A nrPDB 52 2e-07 2C3Q-A nrPDB 52 2e-07 3BBY-A nrPDB 52 2e-07 3TOT-A nrPDB 52 3e-07 5F07-A nrPDB 51 3e-07 1B48-A nrPDB 50 6e-07 5ELG-A nrPDB 50 1e-06 3IBH-A nrPDB 49 1e-06 1AXD-A nrPDB 49 1e-06 3GX0-A nrPDB 48 4e-06 5LCZ-A nrPDB 47 4e-06 2PMT-A nrPDB 47 7e-06 5LOL-A nrPDB 47 7e-06 3PR8-A nrPDB 47 9e-06 3C8E-A nrPDB 46 1e-05 5G5A-A nrPDB 45 3e-05 6EP7-A nrPDB 45 3e-05 1AW9-A nrPDB 45 3e-05 5A5K-A nrPDB 45 3e-05 4AGS-A nrPDB 43 9e-05 2IL3-A nrPDB 43 1e-04 4MDC-A nrPDB 43 1e-04 1U3I-A nrPDB 42 1e-04 4Q5F-A nrPDB 42 1e-04 4RI7-A nrPDB 42 1e-04 5IQY-A nrPDB 42 2e-04 5Y7I-A nrPDB 42 2e-04 2AAW-A nrPDB 40 8e-04 4MPF-A nrPDB 40 0.001 3R2Q-A nrPDB 40 0.001 3LSZ-A nrPDB 39 0.001 5N9U-A nrPDB 39 0.001 5NR1-A nrPDB 37 0.005 5F05-A nrPDB 37 0.007 1OYJ-A nrPDB 37 0.007 1N2A-A nrPDB 36 0.016 1G6W-A nrPDB 34 0.040 3KXO-A nrPDB 34 0.045 2R5G-A nrPDB 34 0.048 1M0U-A nrPDB 33 0.078 3FY7-A nrPDB 32 0.15 5Y9Z-A nrPDB 32 0.24 2CA8-A nrPDB 32 0.26 3CLM-A nrPDB 30 0.81 2FHE-A nrPDB 30 0.90 4GRS-A nrPDB 30 1.1 2X7G-A nrPDB 30 1.2 2HNL-A nrPDB 28 3.2 4C1L-A nrPDB 28 3.5 >2CZ2-A nrPDB Length = 223 Score = 444 bits (1143), Expect = e-125, Method: Compositional matrix adjust. Identities = 216/216 (100%), Positives = 216/216 (100%) Query: 1 MQAGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVP 60 MQAGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVP Sbjct: 8 MQAGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVP 67 Query: 61 ALKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLK 120 ALKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLK Sbjct: 68 ALKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLK 127 Query: 121 QVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDL 180 QVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDL Sbjct: 128 QVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDL 187 Query: 181 SPYPTISHINKELLALEVFQVSHPRRQPDTPAELRT 216 SPYPTISHINKELLALEVFQVSHPRRQPDTPAELRT Sbjct: 188 SPYPTISHINKELLALEVFQVSHPRRQPDTPAELRT 223 >1FW1-A nrPDB Length = 216 Score = 384 bits (986), Expect = e-107, Method: Compositional matrix adjust. Identities = 184/215 (85%), Positives = 196/215 (91%) Query: 1 MQAGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVP 60 MQAGKPILYSYFRSSCSWRVRIALALKGIDY+ VPINLIKDGGQQF+++FQ LNPMKQVP Sbjct: 1 MQAGKPILYSYFRSSCSWRVRIALALKGIDYKTVPINLIKDGGQQFSKDFQALNPMKQVP 60 Query: 61 ALKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLK 120 LKIDGITI QSLAI+EYLEETRP PRLLPQDP+KRA VRMISDLIA GIQPLQNLSVLK Sbjct: 61 TLKIDGITIHQSLAIIEYLEETRPTPRLLPQDPKKRASVRMISDLIAGGIQPLQNLSVLK 120 Query: 121 QVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDL 180 QVG+E Q+ WAQ IT GFNALE+ILQSTAG YCVGDEV+MAD+CLVPQVANAERFKVDL Sbjct: 121 QVGEEMQLTWAQNAITCGFNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAERFKVDL 180 Query: 181 SPYPTISHINKELLALEVFQVSHPRRQPDTPAELR 215 +PYPTIS INK LL LE FQVSHP RQPDTP ELR Sbjct: 181 TPYPTISSINKRLLVLEAFQVSHPCRQPDTPTELR 215 >1E6B-A nrPDB Length = 221 Score = 197 bits (500), Expect = 4e-51, Method: Compositional matrix adjust. Identities = 98/210 (46%), Positives = 137/210 (65%), Gaps = 7/210 (3%) Query: 8 LYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGI 67 LYSY+RSSC+ RVRIALALKG+DYE +P+NL+K G QF +F+ +NPM VPAL + Sbjct: 11 LYSYWRSSCAHRVRIALALKGLDYEYIPVNLLK--GDQFDSDFKKINPMGTVPALVDGDV 68 Query: 68 TIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLK----QVG 123 I S AI+ YL+E P P LLP+D KRA+ ++ SGIQP QNL+V++ ++ Sbjct: 69 VINDSFAIIMYLDEKYPEPPLLPRDLHKRAVNYQAMSIVLSGIQPHQNLAVIRYIEEKIN 128 Query: 124 QENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANA-ERFKVDLSP 182 E + W IT GF ALEK+L + AGK+ GDE+ +AD+ L PQ+ A RF++++ P Sbjct: 129 VEEKTAWVNNAITKGFTALEKLLVNCAGKHATGDEIYLADLFLAPQIHGAINRFQINMEP 188 Query: 183 YPTISHINKELLALEVFQVSHPRRQPDTPA 212 YPT++ + L FQ + P +QPD P+ Sbjct: 189 YPTLAKCYESYNELPAFQNALPEKQPDAPS 218 >4IGJ-A nrPDB Length = 242 Score = 186 bits (473), Expect = 5e-48, Method: Compositional matrix adjust. Identities = 97/211 (45%), Positives = 135/211 (63%), Gaps = 9/211 (4%) Query: 8 LYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKI--D 65 LYSY+RSS +WRVR+ LALKG+ YE ++L+ +QF Q NPM QVP L++ D Sbjct: 27 LYSYWRSSSAWRVRLGLALKGLAYEYRAVDLLAQ--EQFQAAHQARNPMSQVPVLEVEED 84 Query: 66 GIT--IVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVG 123 G T +VQS+AI+E+LEE P P LLP D RA VR +++ + SG QP+QN VL+ + Sbjct: 85 GRTHLLVQSMAILEWLEERHPEPALLPPDLWGRARVRALAEHVNSGTQPMQNALVLRMLR 144 Query: 124 QE---NQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDL 180 ++ +WA+ I G ALE ++ AG++ GD ++AD LVPQ+ NA RF +DL Sbjct: 145 EKVPGWDREWARFFIARGLAALETAVRDGAGRFSHGDAPTLADCYLVPQLYNARRFGLDL 204 Query: 181 SPYPTISHINKELLALEVFQVSHPRRQPDTP 211 PYPT+ +++ AL FQ +HP RQPD P Sbjct: 205 EPYPTLRRVDEACAALAPFQAAHPDRQPDAP 235 >3LG6-A nrPDB Length = 235 Score = 178 bits (451), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 98/225 (43%), Positives = 140/225 (62%), Gaps = 19/225 (8%) Query: 8 LYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGI 67 LY YFRSSCS R+RIA LK I Y P+NL+K G+Q ++ +++LNP VP L + I Sbjct: 12 LYGYFRSSCSGRLRIAFHLKSIPYTRHPVNLLK--GEQHSDTYKSLNPTNTVPLLVVSNI 69 Query: 68 -----------TIVQSLAIMEYLEETRPI---PRLLP-QDPQKRAIVRMISDLIASGIQP 112 +I QSLA +EYLEE P P L P +P RA VR I ++IA +QP Sbjct: 70 NNTVSPSSASFSIGQSLAALEYLEEALPTNARPLLPPISNPVARAHVRTICNIIACDVQP 129 Query: 113 LQNLSVLKQVG--QENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQV 170 + NL + K+V + W++ + T GF A+EK+L+ +AG++CVGDE+++ADVCLVP V Sbjct: 130 VTNLKIQKKVKALDGDPTVWSRDLATQGFGAVEKLLELSAGRFCVGDEITLADVCLVPAV 189 Query: 171 ANAERFKVDLSPYPTISHINKELLALEVFQVSHPRRQPDTPAELR 215 AER +DL+ +P + +E+L E Q +H ++Q DTP +LR Sbjct: 190 WAAERVGMDLARFPITKRVFEEMLKEEAVQKAHWQKQEDTPEDLR 234 >3NIV-A nrPDB Length = 222 Score = 171 bits (432), Expect = 3e-43, Method: Compositional matrix adjust. Identities = 84/207 (40%), Positives = 129/207 (62%), Gaps = 8/207 (3%) Query: 7 ILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDG 66 ILY YFRS+ +RVRIAL LK I YE + ++L+ +GG+Q + ++ +NP + VP+L I+G Sbjct: 4 ILYDYFRSTACYRVRIALNLKKIAYEKIEVHLVNNGGEQHSLQYHQINPQELVPSLDING 63 Query: 67 ITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQV---- 122 + QS+AI++YLEE P LLP+DP +A ++ ++ ++A + PL NL VL ++ Sbjct: 64 QILSQSMAIIDYLEEIHPEMPLLPKDPFMKATLKSMALIVACDMHPLNNLRVLNRLKEQF 123 Query: 123 --GQENQMQWAQKVITSGFNALEKILQSTAGK--YCVGDEVSMADVCLVPQVANAERFKV 178 +E ++W + +GF+A E+ L + C G EV +ADVCL+PQV NA RF Sbjct: 124 NANEEQVLEWYHHWLKTGFDAFEEKLGALERDKPVCFGSEVGLADVCLIPQVYNAHRFHF 183 Query: 179 DLSPYPTISHINKELLALEVFQVSHPR 205 D++ YP I+ IN+ L L F + P Sbjct: 184 DMASYPIINEINEYCLTLPAFHDAAPE 210 >6JWK-A nrPDB Length = 222 Score = 157 bits (398), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 91/210 (43%), Positives = 125/210 (59%), Gaps = 10/210 (4%) Query: 8 LYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPAL-KIDG 66 LYS+F SS S+RVRIALALKG+DY++VP+NL + G+Q + NPM +P L DG Sbjct: 3 LYSFFNSSTSYRVRIALALKGLDYQVVPVNLRQ--GEQLRPADRQRNPMGALPTLVDADG 60 Query: 67 ITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQ-- 124 QSLAI++YL+ +P PRL+P DP RA ++ L+A I PL N+ VLK + Q Sbjct: 61 RRFSQSLAIIDYLDAVQPEPRLIPLDPLHRAQALELALLVACDIHPLNNVRVLKYLTQVL 120 Query: 125 ----ENQMQWAQKVITSGFNALEKIL-QSTAGKYCVGDEVSMADVCLVPQVANAERFKVD 179 E++ +W + G A E +L + G + G + + CLVPQ+ANA R D Sbjct: 121 GIDAEDRQRWYAHWVAEGLAAAETLLNRHRRGAFFAGAAAGIVECCLVPQLANARRMGCD 180 Query: 180 LSPYPTISHINKELLALEVFQVSHPRRQPD 209 L+PYP + + LALE FQ + P RQPD Sbjct: 181 LAPYPALLELEGRCLALEAFQRASPERQPD 210 >2JL4-A nrPDB Length = 213 Score = 151 bits (381), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 82/211 (38%), Positives = 122/211 (57%), Gaps = 10/211 (4%) Query: 8 LYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGI 67 LY+++RS S R+RIAL LKG+ YE + ++L K+ + + F+ LNP + VPAL Sbjct: 4 LYNFWRSGTSHRLRIALNLKGVPYEYLAVHLGKE--EHLKDAFKALNPQQLVPALDTGAQ 61 Query: 68 TIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVL----KQVG 123 ++QS AI+E+LEE P P LLP D R VR ++ ++ I P+ N +L K G Sbjct: 62 VLIQSPAIIEWLEEQYPTPALLPADADGRQRVRALAAIVGCDIHPINNRRILEYLRKTFG 121 Query: 124 QENQM--QWAQKVITSGFNALEKIL--QSTAGKYCVGDEVSMADVCLVPQVANAERFKVD 179 + W I++GF+A E +L G+Y GD ++AD LVPQV +A RF+VD Sbjct: 122 ADEAAINAWCGTWISAGFDAYEALLAVDPKRGRYSFGDTPTLADCYLVPQVESARRFQVD 181 Query: 180 LSPYPTISHINKELLALEVFQVSHPRRQPDT 210 L+PYP I ++ L+ F+ + P QPD+ Sbjct: 182 LTPYPLIRAVDAACGELDAFRRAAPAAQPDS 212 >4PXO-A nrPDB Length = 238 Score = 139 bits (351), Expect = 8e-34, Method: Compositional matrix adjust. Identities = 84/214 (39%), Positives = 125/214 (58%), Gaps = 11/214 (5%) Query: 8 LYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPAL-KIDG 66 +Y +RS+ ++RVRIAL LKGI YE V ++L D G Q +F +NP VPAL DG Sbjct: 26 MYGNWRSAAAFRVRIALNLKGIAYEEVFLDL--DAGDQHKPDFLAINPQGAVPALFDGDG 83 Query: 67 ITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQ----NLSVLKQV 122 + QSLAI++YLEETR LLP++P+ RA R ++ ++A PL +++ Sbjct: 84 PPLTQSLAILDYLEETRTGVPLLPEEPRARARARSLAQVVACDTHPLYVPRVRTFLMENY 143 Query: 123 G--QENQMQWAQKVITSGFNALEKILQSTAG--KYCVGDEVSMADVCLVPQVANAERFKV 178 G +E +++ + +G LE L + AG ++C GD VS AD+CL+ F + Sbjct: 144 GLPRERMLEFLRNAFITGLKTLETRLSNEAGTGRFCQGDAVSHADLCLISLWVGTGIFGI 203 Query: 179 DLSPYPTISHINKELLALEVFQVSHPRRQPDTPA 212 D + YPT+ I++E+LAL+ +HP RQP PA Sbjct: 204 DTAAYPTVKRISEEVLALDAVARAHPLRQPGAPA 237 >4QQ7-A nrPDB Length = 207 Score = 73.2 bits (178), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 54/178 (30%), Positives = 85/178 (47%), Gaps = 12/178 (6%) Query: 7 ILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDG 66 +LYS S R R+ L KG+D+EI ++L E+ +NP QVP L Sbjct: 7 VLYSGTTCPFSQRCRLVLFEKGMDFEIRDVDLFNK-----PEDISVMNPYGQVPILVERD 61 Query: 67 ITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVL---KQVG 123 + + +S I EY++E P P+L+P DP +RA R+ L+ + ++S L K Sbjct: 62 LILYESNIINEYIDERFPHPQLMPADPVQRARARLF--LLNFEKELFVHVSTLENEKGKA 119 Query: 124 QENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDLS 181 E + A+ I L I KY +G+E SM DV + P + + + ++LS Sbjct: 120 AEKNHEKARLAIRDRLTQLAPIF--VKNKYMLGEEFSMLDVAIAPLLWRLDHYGIELS 175 >3M3M-A nrPDB Length = 210 Score = 66.6 bits (161), Expect = 8e-12, Method: Compositional matrix adjust. Identities = 58/208 (27%), Positives = 97/208 (46%), Gaps = 21/208 (10%) Query: 8 LYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKI-DG 66 +Y +RS +++++ L L G+ YE ++++ GG TE F NP ++P L++ DG Sbjct: 6 VYGDYRSGNCYKIKLMLNLLGLPYEWQAVDIL--GGDTQTEAFLAKNPNGKIPVLELEDG 63 Query: 67 ITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQ-- 124 + +S AI+ +L + + LP +P+ R V +P ++ Q+ + Sbjct: 64 TCLWESNAILNFLADGS---QFLPSEPRLRTQVLQWQFFEQYSHEPYIAVARFIQLYEGL 120 Query: 125 -ENQMQWAQKVITSGFNAL---EKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDL 180 E + + K+ G+ AL EK L T Y VG+ S+AD+ L A+ DL Sbjct: 121 PEERREEYLKLHKRGYKALDVMEKQLSRTP--YLVGEHYSIADIALYAYTHVADEGGFDL 178 Query: 181 SPYPTISHINKELLALEVFQVSHPRRQP 208 S YP I + + SHPR P Sbjct: 179 SRYPGIQAWMQRV-------QSHPRHVP 199 >5F0G-A nrPDB Length = 215 Score = 65.9 bits (159), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 53/181 (29%), Positives = 88/181 (48%), Gaps = 15/181 (8%) Query: 14 SSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSL 73 C + +A AL G++ +N ++ G+Q EF LNP +P L +G +I +S Sbjct: 10 GGCRTVIMVAKAL-GLELNKKLLNTME--GEQLKPEFVKLNPQHTIPTLVDNGFSIWESR 66 Query: 74 AIMEYL-EETRPIPRLLPQDPQKRAIV--RMISD---LIASGIQPLQNLSVLKQVGQENQ 127 AI YL E+ LLP DP+KRA++ R+ D L S + L + G + Sbjct: 67 AIAVYLVEKYGKDDYLLPNDPKKRAVINQRLYFDMGTLYESFAKYYYPLFRTGKPGSDED 126 Query: 128 MQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDLSPYPTIS 187 + K I + F L+ L+ +Y GD++++AD+ ++ V+ E + D S Y +S Sbjct: 127 L----KRIETAFGFLDTFLEGQ--EYVAGDQLTVADIAILSTVSTFEVSEFDFSKYSNVS 180 Query: 188 H 188 Sbjct: 181 R 181 >4YH2-A nrPDB Length = 222 Score = 65.5 bits (158), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 59/188 (31%), Positives = 95/188 (50%), Gaps = 13/188 (6%) Query: 20 VRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSLAIMEYL 79 V++ LA + YE V ++++ Q + E+ NP VP L+ DG I S AI+ YL Sbjct: 18 VKLTLAALNLTYEYVNVDIVARA--QLSPEYLEKNPQHTVPTLEDDGHYIWDSHAIIAYL 75 Query: 80 -EETRPIPRLLPQDPQKRAIV--RMISD---LIASGIQPLQNLSVLKQVGQENQMQWAQK 133 + L P+DP KRA+V R+ + + A+GI+ + SVL Q GQ + Sbjct: 76 VSKYADSDALYPKDPLKRAVVDQRLHFESGVVFANGIRSISK-SVLFQ-GQTKVPKERYD 133 Query: 134 VITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERF-KVDLSPYPTISHINKE 192 I ++ +E L+ Y G+++++AD LV VA+ E F +D + YP I K+ Sbjct: 134 AIIEIYDFVETFLKGQ--DYIAGNQLTIADFSLVSSVASLEAFVALDTTKYPRIGAWIKK 191 Query: 193 LLALEVFQ 200 L L ++ Sbjct: 192 LEQLPYYE 199 >4J2F-A nrPDB Length = 223 Score = 65.1 bits (157), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 51/164 (31%), Positives = 76/164 (46%), Gaps = 17/164 (10%) Query: 8 LYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPM-KQVPALKIDG 66 L+ + S S RV AL LKGI YE V +L + NP+ K++P L G Sbjct: 7 LHGAWPSPFSCRVIWALKLKGIPYEYVEEDLFNK-----SPLLLQYNPVHKKIPVLVHGG 61 Query: 67 ITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQEN 126 I +S I+EYL+ET P LLP DP +RA+ R I + N + + G+E Sbjct: 62 KPICESTIILEYLDETWPENPLLPSDPHERAVARFWVKFIEDKGTAIWN--IFRTKGEE- 118 Query: 127 QMQWAQKVITSGFNALEKILQSTAG----KYCVGDEVSMADVCL 166 +K + + L+ I + G KY GD++ + D+ Sbjct: 119 ----LEKAVKNCLEVLKTIEEHAMGVSDDKYFGGDKIGIVDIAF 158 >3WD6-A nrPDB Length = 256 Score = 64.7 bits (156), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 64/219 (29%), Positives = 107/219 (48%), Gaps = 30/219 (13%) Query: 4 GKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALK 63 GK +Y+ + R +AL K IDYE+V I+LI D + T T + +VPA++ Sbjct: 28 GKLRVYNMRYCPYAQRTILALNAKQIDYEVVNIDLI-DKPEWLT----TKSAFAKVPAIE 82 Query: 64 I-DGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNL--SVLK 120 I + +TI +SL +EYL+E P LLPQDP K+A+ ++I + A P+Q+L +LK Sbjct: 83 IAEDVTIYESLVTVEYLDEVYPKRPLLPQDPLKKALDKIIVEASA----PIQSLFIKILK 138 Query: 121 QVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVP------QVANAE 174 N+ A + +++ L++ + G E AD + P A+ E Sbjct: 139 FSDTVNEEHVA--AYHKALDFIQEQLKNRGTVFLDGSEPGYADYMIWPWFERLRAFAHDE 196 Query: 175 RFKVDLSPYPTI----------SHINKELLALEVFQVSH 203 R +++ S Y + S +++ L+ LE+ H Sbjct: 197 RVRLEPSKYSLLLEYIDNMLKDSAVSQYLIPLEILAKFH 235 >4PNG-A nrPDB Length = 229 Score = 64.3 bits (155), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 59/201 (29%), Positives = 96/201 (47%), Gaps = 9/201 (4%) Query: 5 KPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKI 64 K ILY S V++ LA + YE V +N + F+EEF NP VP L+ Sbjct: 9 KLILYGLEASPPVRAVKLTLAALEVPYEFVEVN--TRAKENFSEEFLKKNPQHTVPTLED 66 Query: 65 DGITIVQSLAIMEYL-EETRPIPRLLPQDPQKRAIV--RMISDLIASGIQPLQNLSVLKQ 121 DG I S AI+ YL + L P+D +RA+V R+ + L++++ Sbjct: 67 DGHYIWDSHAIIAYLVSKYGKTDSLYPKDLLQRAVVDQRLHFESGVIFANALRSITKPLF 126 Query: 122 VGQENQM-QWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERF-KVD 179 G++ + + I ++ LEK L Y G+++++AD ++ V++ E F KVD Sbjct: 127 AGKQTMIPKERYDAIIEVYDFLEKFL--AGNDYVAGNQLTIADFSIISTVSSLEVFVKVD 184 Query: 180 LSPYPTISHINKELLALEVFQ 200 + YP I+ K L L ++ Sbjct: 185 TTKYPRIAAWFKRLQKLPYYE 205 >1PN9-A nrPDB Length = 209 Score = 63.9 bits (154), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 49/183 (26%), Positives = 87/183 (47%), Gaps = 9/183 (4%) Query: 9 YSYFRSSCSWR-VRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGI 67 + Y S R V++ A G++ + +L+K G+ EF LNP +P L +G Sbjct: 3 FYYLPGSAPCRAVQMTAAAVGVELNLKLTDLMK--GEHMKPEFLKLNPQHCIPTLVDNGF 60 Query: 68 TIVQSLAIMEYL-EETRPIPRLLPQDPQKRAIV--RMISDLIASGIQPLQNLSVLKQVGQ 124 + +S AI YL E+ +L P+DPQKRA+V R+ D+ + Q + + + Sbjct: 61 ALWESRAIQIYLAEKYGKDDKLYPKDPQKRAVVNQRLYFDM-GTLYQRFADYHYPQIFAK 119 Query: 125 ENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDLSPYP 184 + +K + L L+ +Y G+++++AD+ L +A E D +PYP Sbjct: 120 QPANPENEKKMKDAVGFLNTFLEGQ--EYAAGNDLTIADLSLAATIATYEVAGFDFAPYP 177 Query: 185 TIS 187 ++ Sbjct: 178 NVA 180 >2VCV-A nrPDB Length = 222 Score = 63.2 bits (152), Expect = 8e-11, Method: Compositional matrix adjust. Identities = 61/217 (28%), Positives = 103/217 (47%), Gaps = 22/217 (10%) Query: 3 AGKPILYSYFRSSCSWR-VRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPA 61 AGKP L+ YF +R LA G+++E I +D G+ + +QVP Sbjct: 2 AGKPKLH-YFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMF---QQVPM 57 Query: 62 LKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQ 121 ++IDG+ +VQ+ AI+ Y+ L +D ++RA++ D+ G+ L + +L Sbjct: 58 VEIDGMKLVQTRAILNYIASKY---NLYGKDIKERALI----DMYTEGMADLNEMILLLP 110 Query: 122 VG--QENQMQWA---QKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERF 176 + +E + A +K + F A EK+LQS Y VG+++S AD+ LV + E Sbjct: 111 LCRPEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEEL 170 Query: 177 KVDL-SPYPTISHINKELLAL----EVFQVSHPRRQP 208 L S +P + + + L + Q PR+ P Sbjct: 171 DSSLISNFPLLKALKTRISNLPTVKKFLQPGSPRKPP 207 >4CHS-A nrPDB Length = 219 Score = 62.4 bits (150), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 57/188 (30%), Positives = 84/188 (44%), Gaps = 19/188 (10%) Query: 7 ILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPM-KQVPALKID 65 +L ++ S RVRIALA KGI+YE +L + + +NP+ K++P L + Sbjct: 6 VLLDFWPSPFGMRVRIALAEKGIEYEYKEEDL-----RNKSPLLLQMNPVHKKIPVLIHN 60 Query: 66 GITIVQSLAIMEYLEETRPIPR-LLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQ 124 G I +SL ++Y+EE LLP DP +RA R +D + I L + G+ Sbjct: 61 GKPISESLIAVQYIEEVWNDRNPLLPSDPYQRAQARFWADYVDIKIHDLGK-KIWTSKGE 119 Query: 125 ENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDLSPYP 184 E + A+K LE+ L Y GD + D+ LVP F Y Sbjct: 120 EKEA--AKKEFIEALKLLEEQLGDKT--YFGGDNIGFVDIALVP-------FYTWFKVYE 168 Query: 185 TISHINKE 192 T +N E Sbjct: 169 TFGSLNIE 176 >3UBL-A nrPDB Length = 242 Score = 62.0 bits (149), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 40/147 (27%), Positives = 82/147 (55%), Gaps = 10/147 (6%) Query: 19 RVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSLAIMEY 78 +V++ + KG++YE + I ++ E+F ++PM ++P L++DG I +S AI+E+ Sbjct: 17 KVKLGILEKGLEYEQIRIAPSQE------EDFLKISPMGKIPVLEMDGKFIFESGAILEF 70 Query: 79 LEETRP-IPRLLPQDPQKRAIVRMISDLIASGIQ-PLQNLSVLKQVGQENQMQWAQKVIT 136 L+ P P+L+P+DP + A VR IS +I + + P + + + ++ + Sbjct: 71 LDTIFPQTPKLIPEDPWEAARVREISTIIETYLDIPARRIYLPAAKVSPEIVEEVHSTLV 130 Query: 137 SGFNALEKILQSTAGKYCVGDEVSMAD 163 G AL+++++ + Y G+ ++AD Sbjct: 131 KGIKALQRVVRFSP--YIAGNVFTLAD 155 >2VO4-A nrPDB Length = 219 Score = 62.0 bits (149), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 57/188 (30%), Positives = 83/188 (44%), Gaps = 19/188 (10%) Query: 7 ILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPM-KQVPALKID 65 +L ++ S RVRIALA KGI YE +L + + +NP+ K++P L + Sbjct: 6 VLLDFWPSPFGMRVRIALAEKGIKYEYKEEDL-----RNKSPLLLQMNPVHKKIPVLIHN 60 Query: 66 GITIVQSLAIMEYLEETRPIPR-LLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQ 124 G I +SL ++Y+EE LLP DP +RA R +D + I L + G+ Sbjct: 61 GKPICESLIAVQYIEEVWNDRNPLLPSDPYQRAQTRFWADYVDKKIYDLGR-KIWTSKGE 119 Query: 125 ENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDLSPYP 184 E + A+K LE+ L Y GD + D+ LVP F Y Sbjct: 120 EKEA--AKKEFIEALKLLEEQLGDKT--YFGGDNLGFVDIALVP-------FYTWFKAYE 168 Query: 185 TISHINKE 192 T +N E Sbjct: 169 TFGTLNIE 176 >1VF1-A nrPDB Length = 229 Score = 61.2 bits (147), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 56/214 (26%), Positives = 105/214 (49%), Gaps = 17/214 (7%) Query: 3 AGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQT-LNPMKQVPA 61 A KP+LY + +R LA G+++E V + + +Q+ + Q+ + +QVP Sbjct: 2 AAKPVLYYFNGRGKMESIRWLLAAAGVEFEEVFL----ETREQYEKLLQSGILMFQQVPM 57 Query: 62 LKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMI---SDLIASGIQPLQNLSV 118 ++IDG+ +VQ+ AI+ Y+ L +D ++RA++ M +D + + LS Sbjct: 58 VEIDGMKLVQTRAILNYIAGKY---NLYGKDLKERALIDMYVGGTDDLMGFLLSFPFLSA 114 Query: 119 LKQVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKV 178 +V Q + +K + F A EK+L+ + VG+ +S AD+ L+ + E K Sbjct: 115 EDKVKQCAFV--VEKATSRYFPAYEKVLKDHGQDFLVGNRLSWADIHLLEAILMVEEKKS 172 Query: 179 D-LSPYPTISHINKELLA---LEVFQVSHPRRQP 208 D LS +P + K + + ++ F +R+P Sbjct: 173 DALSGFPLLQAFKKRISSIPTIKKFLAPGSKRKP 206 >5J5N-A nrPDB Length = 231 Score = 60.8 bits (146), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 55/194 (28%), Positives = 86/194 (44%), Gaps = 19/194 (9%) Query: 1 MQAGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPM-KQV 59 M + + L ++ S RVR+ALA KG+ YE +L +NP+ KQ+ Sbjct: 12 MASDQVTLLDFWPSPFGMRVRLALAEKGVKYEYSEEDLWNKSAL-----LLQMNPVNKQI 66 Query: 60 PALKIDGITIVQSLAIMEYLEET-RPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSV 118 P L +G + +SL I++Y++E + LLP DP +RA R +D + I L + Sbjct: 67 PVLVHNGKPVCESLIIVQYIDEVWKDSAPLLPSDPYQRAQSRFWADFVDKKIYDLGR-KI 125 Query: 119 LKQVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKV 178 + G+E + A+K +E L Y G+ + D+ LVP F Sbjct: 126 WTKKGEEQEA--AKKDFIDSLKLMEGELGDKP--YFGGETIGYVDIALVP-------FYS 174 Query: 179 DLSPYPTISHINKE 192 Y TI + N E Sbjct: 175 WFYAYETIGNFNIE 188 >3VWX-A nrPDB Length = 222 Score = 60.5 bits (145), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 58/186 (31%), Positives = 89/186 (47%), Gaps = 15/186 (8%) Query: 24 LALKGID--YEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSLAIMEYL-E 80 L LK ++ +E +NL + +EE+ NP VP L+ DG I S AIM YL Sbjct: 20 LTLKALNLPFEYKVVNLF--AKEHLSEEYLKKNPQHTVPTLEEDGHLIWDSHAIMAYLVS 77 Query: 81 ETRPIPRLLPQDPQKRAIV--RMISD---LIASGIQPLQNLSVLKQVGQENQMQWAQKVI 135 + L P+D KRA+V RM + L G++ + + Q Q Q V Sbjct: 78 KYGKDDSLYPKDLLKRAVVDQRMYFEAGVLFQGGLRNITAPLFFRNQTQIPQHQIDSIVE 137 Query: 136 TSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERF-KVDLSPYPTISHINKELL 194 + GF LE L++ KY GD +++AD +V V + F ++D S +P +S K L Sbjct: 138 SYGF--LESFLKNN--KYMAGDHLTIADFSIVTSVTSLVAFAEIDQSKFPKLSAWLKSLQ 193 Query: 195 ALEVFQ 200 +L ++ Sbjct: 194 SLPFYE 199 >1F3B-A nrPDB Length = 222 Score = 60.5 bits (145), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 56/207 (27%), Positives = 96/207 (46%), Gaps = 30/207 (14%) Query: 3 AGKPILYSYF----RSSCSWRVRIALALKGIDYEIVPI-------NLIKDGGQQFTEEFQ 51 AGKP+L+ YF R C +R LA G+++E I L KDG F Sbjct: 1 AGKPVLH-YFNARGRMEC---IRWLLAAAGVEFEEKFIQSPEDLEKLKKDGNLMFD---- 52 Query: 52 TLNPMKQVPALKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQ 111 QVP ++IDG+ + Q+ AI+ Y+ L +D ++RA++ M S+ I + Sbjct: 53 ------QVPMVEIDGMKLAQTRAILNYIATKYD---LYGKDMKERALIDMYSEGILDLTE 103 Query: 112 PLQNLSVLKQVGQENQMQWAQKVITSGF-NALEKILQSTAGKYCVGDEVSMADVCLVPQV 170 + L + +E + A+ + + A EK+L+S Y VG+ ++ D+ L+ + Sbjct: 104 MIGQLVLCPPDQREAKTALAKDRTKNRYLPAFEKVLKSHGQDYLVGNRLTRVDIHLLEVL 163 Query: 171 ANAERFKVD-LSPYPTISHINKELLAL 196 E F L+P+P + + +L Sbjct: 164 LYVEEFDASLLTPFPLLKAFKSRISSL 190 >3QAG-A nrPDB Length = 239 Score = 59.7 bits (143), Expect = 9e-10, Method: Compositional matrix adjust. Identities = 46/172 (26%), Positives = 79/172 (45%), Gaps = 8/172 (4%) Query: 8 LYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKID-G 66 +YS S R R+ L K I +E+V INL + E + T +P +P L+ Sbjct: 26 IYSMRFCPYSHRTRLVLKAKDIRHEVVNINL-----RNKPEWYYTKHPFGHIPVLETSQS 80 Query: 67 ITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQEN 126 I +S+ EYL++ P +L P DP +RA +M+ +L + + V + G+E+ Sbjct: 81 QLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFSKVPHLTKECLVALRSGRES 140 Query: 127 QMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKV 178 + + F+ LE+IL+ + G +SM D L P + + + Sbjct: 141 TN--LKAALRQEFSNLEEILEYQNTTFFGGTSISMIDYLLWPWFERLDVYGI 190 >3LFL-A nrPDB Length = 240 Score = 59.7 bits (143), Expect = 9e-10, Method: Compositional matrix adjust. Identities = 48/162 (29%), Positives = 76/162 (46%), Gaps = 10/162 (6%) Query: 19 RVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKID-GITIVQSLAIME 77 R R+ L KGI +E++ INL + E F NP VP L+ G I +S E Sbjct: 37 RTRLVLKAKGIRHEVININL-----KNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCE 91 Query: 78 YLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQKVITS 137 YL+E P +LLP DP ++A +MI +L + P S ++ +E+ ++ Sbjct: 92 YLDEAYPGKKLLPDDPYEKACQKMILELFSK--VPSLVGSFIRSQNKEDYAGLKEE-FRK 148 Query: 138 GFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVD 179 F LE +L + + G+ +SM D + P E K++ Sbjct: 149 EFTKLE-VLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLN 189 >1JLV-A nrPDB Length = 209 Score = 59.3 bits (142), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 44/171 (25%), Positives = 82/171 (47%), Gaps = 8/171 (4%) Query: 20 VRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSLAIMEYL 79 V++ A G++ + NL+ G+ EF +NP +P L +G + +S AI YL Sbjct: 15 VQMTAAAVGVELNLKLTNLM--AGEHMKPEFLKINPQHCIPTLVDNGFALWESRAICTYL 72 Query: 80 -EETRPIPRLLPQDPQKRAIV--RMISDLIASGIQPLQNLSVLKQVGQENQMQWAQKVIT 136 E+ +L P+DPQKRA+V R+ D+ + Q + + ++ +K + Sbjct: 73 AEKYGKDDKLYPKDPQKRAVVNQRLYFDM-GTLYQRFADYYYPQIFAKQPANAENEKKMK 131 Query: 137 SGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDLSPYPTIS 187 + L L KY GD +++AD+ ++ V+ + +L+ YP ++ Sbjct: 132 DAVDFLNTFLDGH--KYVAGDSLTIADLTVLATVSTYDVAGFELAKYPHVA 180 >5ECL-B nrPDB Length = 223 Score = 58.9 bits (141), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 48/176 (27%), Positives = 74/176 (42%), Gaps = 30/176 (17%) Query: 3 AGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPM------ 56 A PIL Y+ S R R+AL KG+++E E+F +P+ Sbjct: 8 ANLPILLDYWPSMFGMRARVALREKGVEFEYR------------EEDFSNKSPLLLQSNP 55 Query: 57 --KQVPALKIDGITIVQSLAIMEYLEETRPIPR-LLPQDPQKRAIVRMISDLIASGIQPL 113 K++P L +G + +SL +++Y++E P P DP RA R +D + Sbjct: 56 IHKKIPVLVHNGKPVCESLNVVQYVDEAWPEKNPFFPSDPYGRAQARFWADFVDKKFTDA 115 Query: 114 QNLSVLKQVGQENQMQWAQKVITSGFNALEKILQSTAGK--YCVGDEVSMADVCLV 167 Q V + G+E Q+ F KIL+S G Y GD D+ L+ Sbjct: 116 Q-FKVWGKKGEE------QEAGKKEFIEAVKILESELGDKPYFGGDSFGYVDISLI 164 >3I6A-A nrPDB Length = 222 Score = 58.9 bits (141), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 58/224 (25%), Positives = 102/224 (45%), Gaps = 20/224 (8%) Query: 3 AGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPAL 62 A KP L+ + R LA G+++E I +D + + + +QVP + Sbjct: 2 AEKPKLHYFNGRGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMF---QQVPMV 58 Query: 63 KIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQV 122 +IDG+ +VQ+ AI+ Y+ L +D ++RA++ D+ GI L + ++ Sbjct: 59 EIDGMKLVQTRAILNYIASKY---NLYGKDIKERALI----DMYIEGIADLGEMIIMLPF 111 Query: 123 G--QENQMQWA---QKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFK 177 +E + A +K+ F A EK+L+S Y VG+++S AD+ LV + E Sbjct: 112 CPPEEKDAKLALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELD 171 Query: 178 VDL-SPYPTISHINKELLAL----EVFQVSHPRRQPDTPAELRT 216 L S +P + + + L + Q PR+ P +RT Sbjct: 172 SSLISSFPLLKALKTRISNLPTVKKFLQPGSPRKPPPDEIYVRT 215 >3UAR-A nrPDB Length = 227 Score = 58.9 bits (141), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 51/183 (27%), Positives = 84/183 (45%), Gaps = 15/183 (8%) Query: 11 YFRSSCSWRVRIALALKGIDYEIVPINL-IKDGGQQFTEEFQTLNPMKQVPALKID-GIT 68 YF +CS I L G+D+E+ ++L K G +F +NP VPAL++D G Sbjct: 7 YFPGACSLAPHIVLREAGLDFELENVDLGTKKTGS--GADFLQVNPKGYVPALQLDDGQV 64 Query: 69 IVQSLAIMEYLEETRPIPRLLP-----QDPQKRAIVRMISDLIASGIQPLQNLSVLKQVG 123 + + I++YL + +P L+P + + + IS I P N Sbjct: 65 LTEDQVILQYLADLKPESGLMPPSGTFERYRLLEWLAFISTEIHKTFGPFWNPE-----S 119 Query: 124 QENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDLSPY 183 E Q A +++ + +E L++ G + +GD S+AD L + E K+DLS + Sbjct: 120 PEASKQIALGLLSRRLDYVEDRLEA-GGPWLMGDRYSVADAYLSTVLGWCEYLKIDLSKW 178 Query: 184 PTI 186 P I Sbjct: 179 PRI 181 >1PL2-A nrPDB Length = 222 Score = 58.5 bits (140), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 58/216 (26%), Positives = 99/216 (45%), Gaps = 20/216 (9%) Query: 3 AGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPAL 62 A KP L+ + R LA G+++E I +D + + + +QVP + Sbjct: 2 AEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMF---QQVPMV 58 Query: 63 KIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQV 122 +IDG+ +VQ AI+ Y+ L +D ++RA++ D+ GI L + +L V Sbjct: 59 EIDGMKLVQERAILNYIASKY---NLYGKDIKERALI----DMYIEGIADLGEMILLLPV 111 Query: 123 G--QENQMQWA---QKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFK 177 +E + A +K+ F A EK+L+S Y VG+++S AD+ LV + E Sbjct: 112 CPPEEKDAKLALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELD 171 Query: 178 VDL-SPYPTISHINKELLAL----EVFQVSHPRRQP 208 L S +P + + + L + Q PR+ P Sbjct: 172 SSLISSFPLLKALKTRISNLPTVKKFLQPGSPRKPP 207 >2GDR-A nrPDB Length = 202 Score = 58.5 bits (140), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 51/200 (25%), Positives = 90/200 (45%), Gaps = 22/200 (11%) Query: 11 YFRSSCSWRVRIALALKGIDYEIVPINLIKD---GGQQFTEEFQTLNPMKQVPALKID-G 66 Y +CS IAL G+++E+V ++L GQ + E +NP VP L++D G Sbjct: 5 YSPGACSLSPHIALREAGLNFELVQVDLASKKTASGQDYLE----VNPAGYVPCLQLDDG 60 Query: 67 ITIVQSLAIMEYLEETRPIPRLLPQDP-----QKRAIVRMISDLIASGIQPLQNLSVLKQ 121 T+ + AI++Y+ + P +L P + + + IS + PL N + Sbjct: 61 RTLTEGPAIVQYVADQVPGKQLAPANGSFERYHLQQWLNFISSELHKSFSPLFNPA---- 116 Query: 122 VGQENQMQWAQKVITSGFNALEKIL-QSTAGKYCVGDEVSMADVCLVPQVANAERFKVDL 180 + +W V S L ++ Q Y +GD++S+AD+ L + + +DL Sbjct: 117 ----SSDEWKNAVRQSLNTRLGQVARQLEHAPYLLGDQLSVADIYLFVVLGWSAYVNIDL 172 Query: 181 SPYPTISHINKELLALEVFQ 200 SP+P++ + E Q Sbjct: 173 SPWPSLQAFQGRVGGREAVQ 192 >3MAK-A nrPDB Length = 209 Score = 58.5 bits (140), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 42/149 (28%), Positives = 69/149 (46%), Gaps = 6/149 (4%) Query: 42 GGQQFTEEFQTLNPMKQVPALKIDGITIVQSLAIMEYL-EETRPIPRLLPQDPQKRAIV- 99 G+ EF +NP +P L +G + +S AI YL E+ L P+ P+KRA++ Sbjct: 36 AGEHLKPEFLKINPQHTIPTLVDNGFALWESRAIQVYLVEKYGKTDSLYPKCPKKRAVIN 95 Query: 100 -RMISDLIASGIQPLQNLSVLKQVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDE 158 R+ D+ + Q N + + A K I + F L L+ Y GD Sbjct: 96 QRLYFDM-GTLYQSFANYYYPQVFAKAPADPEAFKKIEAAFEFLNTFLEGQ--DYAAGDS 152 Query: 159 VSMADVCLVPQVANAERFKVDLSPYPTIS 187 +++AD+ LV V+ E K ++S Y ++ Sbjct: 153 LTVADIALVATVSTFEVAKFEISKYANVN 181 >1V2A-A nrPDB Length = 210 Score = 57.0 bits (136), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 42/139 (30%), Positives = 70/139 (50%), Gaps = 11/139 (7%) Query: 53 LNPMKQVPALKIDGITIVQSLAIMEYLEETRPIP-RLLPQDPQKRAIV--RMISDL--IA 107 LNP +P L +G + +S AI+ YL ET L P+DP+ R++V R+ D+ + Sbjct: 45 LNPQHTIPTLVDNGHVVWESYAIVLYLVETYAKDDTLYPKDPKVRSVVNQRLFFDIGTLY 104 Query: 108 SGIQPLQNLSVLKQVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLV 167 I + +L + K+ + QM+ + + LE+ + A Y D +++AD+CL+ Sbjct: 105 KRIIDVIHLVMKKEQPSDEQME----KLKGALDLLEQFVTERA--YAAADHLTVADICLL 158 Query: 168 PQVANAERFKVDLSPYPTI 186 V K DL P+P I Sbjct: 159 GTVTALNWLKHDLEPFPHI 177 >2VCT-A nrPDB Length = 222 Score = 56.6 bits (135), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 60/217 (27%), Positives = 100/217 (46%), Gaps = 22/217 (10%) Query: 3 AGKPIL-YSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPA 61 A KP L YS R +R LA G+++E I +D + + + +QVP Sbjct: 2 AEKPKLHYSNIRGRME-SIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMF---QQVPM 57 Query: 62 LKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQ 121 ++IDG+ +VQ+ AI+ Y+ L +D +++A++ D+ GI L + +L Sbjct: 58 VEIDGMKLVQTRAILNYIASKY---NLYGKDIKEKALI----DMYIEGIADLGEMILLLP 110 Query: 122 VGQ--ENQMQWA---QKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERF 176 Q E + A +K F A EK+L+S Y VG+++S AD+ LV + E Sbjct: 111 FTQPEEQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEEL 170 Query: 177 KVDL-SPYPTISHINKELLAL----EVFQVSHPRRQP 208 L S +P + + + L + Q PR+ P Sbjct: 171 DSSLISSFPLLKALKTRISNLPTVKKFLQPGSPRKPP 207 >4MK3-A nrPDB Length = 226 Score = 56.6 bits (135), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 47/163 (28%), Positives = 72/163 (44%), Gaps = 9/163 (5%) Query: 8 LYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKI-DG 66 LY+ S + +VR+ LA K IDYE++ N+ NP+ +VP L + DG Sbjct: 25 LYASQTSPYARKVRVVLAEKKIDYEMIEENVWSPDTT-----IGRFNPLGKVPCLVMEDG 79 Query: 67 ITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRM--ISDLIASGIQPLQNLSVLKQVGQ 124 + S I EY + P+ RL+PQ ++R VR L L V ++ Sbjct: 80 GAVFDSRVIAEYADTLSPVSRLIPQGSRERLEVRCWEALADGLLDAALLARLEVTQRKES 139 Query: 125 ENQMQWAQKVITSGFNALEKILQSTAGK-YCVGDEVSMADVCL 166 E W Q+ + AL + A K +C G ++ADV + Sbjct: 140 ERSESWVQRQRSKIDAALTAMSTGLADKTWCTGTHYTLADVAV 182 >5ZWP-A nrPDB Length = 208 Score = 56.6 bits (135), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 39/151 (25%), Positives = 70/151 (46%), Gaps = 10/151 (6%) Query: 42 GGQQFTEEFQTLNPMKQVPALKIDGITIVQSLAIMEYL-EETRPIPRLLPQDPQKRAIV- 99 G+ EF +NP +P L + +S AIM YL E+ L P+ P+KRA++ Sbjct: 35 AGEHLKPEFLKINPQHTIPTLVDGDFALWESRAIMVYLVEKYGKTDSLFPKCPKKRAVIN 94 Query: 100 -RMISDL--IASGIQPLQNLSVLKQVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVG 156 R+ D+ + + + + ++ K I + F+ L L+ +Y G Sbjct: 95 QRLYFDMGTLYKSFADYYYPQIFAKAPADPELF---KKIETAFDFLNTFLKGH--EYAAG 149 Query: 157 DEVSMADVCLVPQVANAERFKVDLSPYPTIS 187 D +++AD+ L+ V+ E D+S YP ++ Sbjct: 150 DSLTVADLALLASVSTFEVASFDISKYPNVA 180 >1GUL-A nrPDB Length = 222 Score = 56.2 bits (134), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 48/173 (27%), Positives = 83/173 (47%), Gaps = 30/173 (17%) Query: 42 GGQQFTEEF----------QTLNPM--KQVPALKIDGITIVQSLAIMEYLEETRPIPRLL 89 G +F EEF Q N + +QVP ++IDG+ +VQ+ +I+ Y+ + L Sbjct: 26 AGVEFDEEFLETKEQLYKLQDGNHLLFQQVPMVEIDGMKLVQTRSILHYIADKH---NLF 82 Query: 90 PQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQM-QWAQKVITSGFNALEKILQS 148 ++ ++R ++ M + ++ L LK Q+ ++ AQK I F EKIL+ Sbjct: 83 GKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKEVVNMAQKAIIRYFPVFEKILRG 142 Query: 149 TAGKYCVGDEVSMADVCL----------VPQVANA----ERFKVDLSPYPTIS 187 + VG+++S+ADV L +P + +A + + V LS PTI Sbjct: 143 HGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPFLQEYTVKLSNIPTIK 195 >1YQ1-A nrPDB Length = 208 Score = 55.8 bits (133), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 39/170 (22%), Positives = 76/170 (44%), Gaps = 15/170 (8%) Query: 7 ILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDG 66 + Y +FR +R+ L G+ +E V +N Q + + PMKQ+P L IDG Sbjct: 6 LTYFFFRG-LGEPIRLLFHLAGVQFEEVRMN-----PDQTWLDIKDSTPMKQLPVLNIDG 59 Query: 67 ITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQEN 126 + QS AI+ YL + P++ A V + DL + + + ++ G+ Sbjct: 60 FELPQSGAILRYLARKFGFA---GKTPEEEAWVDAVHDLFKDFLAEFKKFAAERRSGKSA 116 Query: 127 Q------MQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQV 170 + ++ + FN L +L+ + + +G +++ AD+ +V + Sbjct: 117 EEVEKFRSEFFLPARNTYFNILNGLLEKSNSGFLIGSDITFADLVVVDNL 166 >5F06-A nrPDB Length = 216 Score = 55.1 bits (131), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 46/170 (27%), Positives = 80/170 (47%), Gaps = 11/170 (6%) Query: 8 LYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGI 67 LY S+C+ RV L K +D+E+VP++L G+ F NP Q+PAL+ D + Sbjct: 4 LYGAPMSTCTSRVLTCLHEKNLDFELVPVDLF--AGEHKQPPFLAKNPFGQIPALEEDDL 61 Query: 68 TIVQSLAIMEYLEET---RPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLK-QVG 123 T+ +S AI Y+ E + ++ ++ A V++ +++ + P V + V Sbjct: 62 TLFESRAITSYIAEKFKGTGYDLIRHENLKEAASVKVWTEVESHRYNPAIAPIVFQFMVA 121 Query: 124 QENQMQWAQKVITSGFNALEKIL-----QSTAGKYCVGDEVSMADVCLVP 168 Q +I L K+L + ++ KY GD S+AD+ +P Sbjct: 122 PLRGNSPDQTIIDDNVEKLGKVLDIYEAKLSSTKYLAGDFYSLADLHHLP 171 >3GH6-A nrPDB Length = 210 Score = 54.7 bits (130), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 42/150 (28%), Positives = 66/150 (44%), Gaps = 12/150 (8%) Query: 44 QQFTEEFQTLNPMKQVPALKIDGITIVQSLAIMEYL-EETRPIPRLLPQDPQKRAIV--R 100 +QFT E+ +NP +P L G + +S AIM YL E+ +L P+D QK+A++ R Sbjct: 38 EQFTPEYLKINPQHTIPTLHDHGFALWESRAIMVYLVEKYGKDDKLFPKDVQKQALINQR 97 Query: 101 MISD---LIASGIQPLQNLSVLKQVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGD 157 + D L S + LK+ E K I F L L+ Y G Sbjct: 98 LYFDMGTLYKSFSEYYYPQIFLKKPANEENY----KKIEVAFEFLNTFLEGQT--YSAGG 151 Query: 158 EVSMADVCLVPQVANAERFKVDLSPYPTIS 187 + S+AD+ + V+ + D Y ++ Sbjct: 152 DYSLADIAFLATVSTFDVAGFDFKRYANVA 181 >1GWC-A nrPDB Length = 230 Score = 54.7 bits (130), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 34/86 (39%), Positives = 51/86 (59%), Gaps = 8/86 (9%) Query: 19 RVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPM-KQVPALKIDGITIVQSLAIME 77 RV++ALALKG+ YE V +L K +E NP+ K++P L +G + +S+ I++ Sbjct: 20 RVKLALALKGLSYEDVEEDLYKK-----SELLLKSNPVHKKIPVLIHNGAPVCESMIILQ 74 Query: 78 YLEE--TRPIPRLLPQDPQKRAIVRM 101 Y++E P LLP DP +RAI R Sbjct: 75 YIDEVFASTGPSLLPADPYERAIARF 100 >1F2E-A nrPDB Length = 201 Score = 53.5 bits (127), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 48/177 (27%), Positives = 85/177 (48%), Gaps = 8/177 (4%) Query: 14 SSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKID-GITIVQS 72 +CS IAL G D+E V ++L + E+F T+NP +VPAL +D G T+ ++ Sbjct: 8 GACSLAPHIALRETGADFEAVKVDLAVRK-TEAGEDFLTVNPSGKVPALTLDSGETLTEN 66 Query: 73 LAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQ-WA 131 AI+ Y+ + P L P + R++S L G + + L ++ + A Sbjct: 67 PAILLYIADQNPASGLAPAEGSLDRY-RLLSRLSFLGSEFHKAFVPLFAPATSDEAKAAA 125 Query: 132 QKVITSGFNALEKILQSTAGK-YCVGDEVSMADVCLVPQVANAERFKVDLSPYPTIS 187 + + + AL+K L AG+ + G+ S+AD+ L + +D++ YP + Sbjct: 126 AESVKNHLAALDKEL---AGRDHYAGNAFSVADIYLYVMLGWPAYVGIDMAAYPALG 179 >1EV4-A nrPDB Length = 221 Score = 53.1 bits (126), Expect = 9e-08, Method: Compositional matrix adjust. Identities = 47/174 (27%), Positives = 83/174 (47%), Gaps = 29/174 (16%) Query: 3 AGKPILYSYF----RSSCSWRVRIALALKGIDYEIVPI-------NLIKDGGQQFTEEFQ 51 +GKP+L+ YF R C +R LA G++++ I L KDG F Sbjct: 1 SGKPVLH-YFNARGRMEC---IRFLLAAAGVEFDEKFIQSPEDLEKLKKDGNLMFD---- 52 Query: 52 TLNPMKQVPALKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQ 111 QVP ++IDG+ + Q+ AI+ Y+ L +D ++RA++ M S+ I + Sbjct: 53 ------QVPMVEIDGMKLAQTRAILNYIATKYD---LYGKDMKERALIDMYSEGILDLTE 103 Query: 112 PLQNLSVLKQVGQENQMQWAQKVITSGF-NALEKILQSTAGKYCVGDEVSMADV 164 + L + +E + A+ + + A EK+L+S Y VG++++ D+ Sbjct: 104 MIMQLVICPPDQKEAKTALAKDRTKNRYLPAFEKVLKSHGQDYLVGNKLTRVDI 157 >6F05-A nrPDB Length = 215 Score = 52.8 bits (125), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 45/160 (28%), Positives = 74/160 (46%), Gaps = 14/160 (8%) Query: 19 RVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSLAIMEY 78 R + L KG+ +E +P++L+K G+ + L P VPA+ I +S A+M Y Sbjct: 15 RALVTLIEKGVAFETIPVDLMK--GEHKQPAYLALQPFGTVPAVVDGDYKIFESRAVMRY 72 Query: 79 LEETRPI--PRLLPQDPQKRAIVRMISDLIASGIQ-PLQNL-------SVLKQVGQENQM 128 + E P LL + + R V D+ A+ PL NL SV+ E + Sbjct: 73 VAEKYRSQGPDLLGKTVEDRGQVEQWLDVEATTYHPPLLNLTLHIMFASVMGFPSDEKLI 132 Query: 129 QWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVP 168 + +++ + + E L + KY GD VS+AD+ +P Sbjct: 133 KESEEKLAGVLDVYEAHLSKS--KYLAGDFVSLADLAHLP 170 >3M8N-A nrPDB Length = 225 Score = 52.4 bits (124), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 50/188 (26%), Positives = 85/188 (45%), Gaps = 15/188 (7%) Query: 8 LYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKID-G 66 LYS RS S++VR+ALAL Y V +++++ G+ T +F NP QVP L+ G Sbjct: 6 LYSMQRSGNSYKVRLALALLDAPYRAVEVDILR--GESRTPDFLAKNPSGQVPLLETAPG 63 Query: 67 ITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLS------VLK 120 + +S AI+ YL L P RA ++P N+ L Sbjct: 64 RYLAESNAILWYLAVG---TSLAPDTRMDRAEALQWMFFEQHALEP--NIGSAYFWLCLV 118 Query: 121 QVGQENQMQWAQKVITSGFNALEKILQS-TAGKYCVGDEVSMADVCLVPQVANAERFKVD 179 + G++ Q + + G+ AL+ + Y ++++AD+ L A++ D Sbjct: 119 KGGRDLQTHALEDWLERGYAALQVMENHLKTNDYFAAGQLTIADIALYGYTHVADQCDFD 178 Query: 180 LSPYPTIS 187 LS +P ++ Sbjct: 179 LSTFPAVN 186 >4PQI-A nrPDB Length = 241 Score = 52.4 bits (124), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 48/187 (25%), Positives = 78/187 (41%), Gaps = 24/187 (12%) Query: 4 GKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALK 63 G LY+ + + RV I KG+ EI + LI + E + P +VP+L+ Sbjct: 31 GTTKLYTCYTCPFAQRVWITRNFKGLQDEIKLVPLILQNRPAWYPE--KVYPPNKVPSLE 88 Query: 64 IDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMI---SDLIASGIQPLQNLSVLK 120 +G +SL +++YLE P LLP+DP K+ + +D + + K Sbjct: 89 HNGKITGESLDLIKYLESNFEGPSLLPKDPAKKEFAEELFSYTDKFNGTVYTAFKGDLAK 148 Query: 121 QVGQENQMQWAQKVITSGFNALEKILQS-TAGKYCVGDEVSMADVCLVPQVAN-----AE 174 + G F+ LE L G + +G E S+ D+ +P V E Sbjct: 149 EAG-------------PAFDHLENALHKFDDGPFFLGKEFSLVDIAYIPFVERLNIFLLE 195 Query: 175 RFKVDLS 181 FK D++ Sbjct: 196 VFKYDIT 202 >2C3Q-A nrPDB Length = 247 Score = 52.0 bits (123), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 30/72 (41%), Positives = 44/72 (61%), Gaps = 3/72 (4%) Query: 29 IDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSLAIMEYLEETRPIP-R 87 I +E+ ++LIK GQ ++ F +NP+K+VPALK T+ +S+AI+ YL +P Sbjct: 33 IPFELRIVDLIK--GQHLSDAFAQVNPLKKVPALKDGDFTLTESVAILLYLTRKYKVPDY 90 Query: 88 LLPQDPQKRAIV 99 PQD Q RA V Sbjct: 91 WYPQDLQARARV 102 >3BBY-A nrPDB Length = 215 Score = 52.0 bits (123), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 34/109 (31%), Positives = 54/109 (49%), Gaps = 5/109 (4%) Query: 10 SYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITI 69 ++F S +AL KG+ + I I+L D G+ +Q ++VP L+ID + Sbjct: 13 AHFFSPYVLSAWVALQEKGLSFHIKTIDL--DSGEHLQPTWQGYGQTRRVPLLQIDDFEL 70 Query: 70 VQSLAIMEYLEETRPIP---RLLPQDPQKRAIVRMISDLIASGIQPLQN 115 +S AI EYLE+ P R+ P D + RA R I + S + P++ Sbjct: 71 SESSAIAEYLEDRFAPPTWERIYPLDLENRARARQIQAWLRSDLMPIRE 119 >3TOT-A nrPDB Length = 226 Score = 51.6 bits (122), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 43/156 (27%), Positives = 77/156 (49%), Gaps = 17/156 (10%) Query: 19 RVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKID-GITIVQSLAIME 77 +VR+ LA K IDY+ V ++ Q NP+ +VP L +D G + S I E Sbjct: 16 KVRVVLAEKKIDYQFVLEDVWNADTQ-----IHQFNPLGKVPCLVMDDGGALFDSRVIAE 70 Query: 78 YLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQM--QWAQKVI 135 Y + P+ RL+P ++R VR L A G L + +V +V Q + Q ++ I Sbjct: 71 YADTLSPVARLIPPSGRERVEVRCWEAL-ADG---LLDAAVALRVEQTQRTPEQRSESWI 126 Query: 136 TSGFNALEKILQSTA-----GKYCVGDEVSMADVCL 166 T + +++ L++ + +C G+ +++AD+ + Sbjct: 127 TRQHHKIDEALKAMSRGLADRTWCNGNHLTLADIAV 162 >5F07-A nrPDB Length = 213 Score = 51.2 bits (121), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 44/166 (26%), Positives = 79/166 (47%), Gaps = 20/166 (12%) Query: 16 CSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSLAI 75 C RV L KG+++++V ++L D G+Q EF P QVP ++ + +S AI Sbjct: 12 CPQRVMACLLEKGVEFDLVHVDL--DSGEQKLPEFLLKQPFGQVPVVEDGDFKLFESRAI 69 Query: 76 MEYLE---ETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQ-----NLSVLKQVGQENQ 127 + Y E R P LL +++A+V ++ A L + +L ++GQ+ Sbjct: 70 IRYYAAKYEDRG-PNLLGNTLEEKALVDQWLEIEAHNFNDLVFNIVFQVVILPRIGQQGD 128 Query: 128 MQWAQKVITSGFNALEKIL-----QSTAGKYCVGDEVSMADVCLVP 168 + ++ + LEK+L + + KY GD ++AD+ +P Sbjct: 129 SE----LVRTYEEKLEKVLDVYEKRLSKSKYLAGDSFTLADLSHLP 170 >1B48-A nrPDB Length = 221 Score = 50.4 bits (119), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 51/198 (25%), Positives = 87/198 (43%), Gaps = 32/198 (16%) Query: 3 AGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMK----- 57 A KP LY + +R LA G+++E ++F E + M+ Sbjct: 1 AAKPKLYYFNGRGRMESIRWLLAAAGVEFE-----------EEFLETREQYEKMQKDGHL 49 Query: 58 ---QVPALKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQ 114 QVP ++IDG+ + Q+ AI+ YL L +D ++R VR+ D+ A G Q L Sbjct: 50 LFGQVPLVEIDGMMLTQTRAILSYLAAKY---NLYGKDLKER--VRI--DMYADGTQDLM 102 Query: 115 NLSVLKQVGQENQMQWAQKVI-----TSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQ 169 + + + + + +I T F EKIL+ + VG+++S AD+ L+ Sbjct: 103 MMIAVAPFKTPKEKEESYDLILSRAKTRYFPVFEKILKDHGEAFLVGNQLSWADIQLLEA 162 Query: 170 VANAERFKVD-LSPYPTI 186 + E LS +P + Sbjct: 163 ILMVEELSAPVLSDFPLL 180 >5ELG-A nrPDB Length = 221 Score = 49.7 bits (117), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 48/188 (25%), Positives = 79/188 (42%), Gaps = 24/188 (12%) Query: 19 RVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSLAIMEY 78 R + L K + Y+I INL D Q F + ++P +VP LKID + S I+ Sbjct: 25 RALLTLEEKSLTYKIHLINL-SDKPQWFLD----ISPQGKVPVLKIDDKWVTDSDVIVGI 79 Query: 79 LEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQKVITSG 138 LEE P P L + ++ + G + N ++ + Sbjct: 80 LEEKYPDPPL-----------KTPAEFASVGSNIFGTFGTFLKSKDSNDG--SEHALLVE 126 Query: 139 FNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAE----RFKVDLSP--YPTISHINKE 192 ALE L+S G + G+ VS D+ L P++ + + FK P +P + + K Sbjct: 127 LEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKT 186 Query: 193 LLALEVFQ 200 L +L+ F+ Sbjct: 187 LFSLDSFE 194 >3IBH-A nrPDB Length = 233 Score = 49.3 bits (116), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 46/164 (28%), Positives = 77/164 (46%), Gaps = 21/164 (12%) Query: 19 RVRIALALKGI--DYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKI-DGITIVQSLAI 75 RVRIALA K + + V INL K G+ EF N VP L++ DG I + AI Sbjct: 32 RVRIALAEKNMLSSVQFVRINLWK--GEHKKPEFLAKNYSGTVPVLELDDGTLIAECTAI 89 Query: 76 MEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQ-----VGQENQM-- 128 EY++ P L + P ++ ++ M++ + ++ L +SV +G E ++ Sbjct: 90 TEYIDALDGTPTLTGKTPLEKGVIHMMNK--RAELELLDPVSVYFHHATPGLGPEVELYQ 147 Query: 129 --QWA---QKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLV 167 +W + G + + +L+ Y GD SMAD+ ++ Sbjct: 148 NKEWGLRQRDKALHGMHYFDTVLRERP--YVAGDSFSMADITVI 189 >1AXD-A nrPDB Length = 209 Score = 48.9 bits (115), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 49/158 (31%), Positives = 75/158 (47%), Gaps = 13/158 (8%) Query: 17 SWRV-RIALALK--GIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSL 73 SW + R A AL+ G DYEIVPIN + + E NP QVPAL+ + + +S Sbjct: 11 SWNLTRCATALEEAGSDYEIVPINFAT--AEHKSPEHLVRNPFGQVPALQDGDLYLFESR 68 Query: 74 AIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQWA-- 131 AI +Y L + ++ A+V + ++ A+ N +L QV + Sbjct: 69 AICKYAARKNKPELLREGNLEEAAMVDVWIEVEANQYTAALN-PILFQVLISPMLGGTTD 127 Query: 132 QKVITSGFNALEKILQS-----TAGKYCVGDEVSMADV 164 QKV+ L+K+L+ T KY GD +S+AD+ Sbjct: 128 QKVVDENLEKLKKVLEVYEARLTKCKYLAGDFLSLADL 165 >3GX0-A nrPDB Length = 215 Score = 47.8 bits (112), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 43/184 (23%), Positives = 83/184 (45%), Gaps = 33/184 (17%) Query: 29 IDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPAL----KIDG---ITIVQSLAIMEYLEE 81 +DY ++ ++L K G QF EF ++P ++PA+ DG +++ +S AI+ YL E Sbjct: 24 LDYRLIKVDLGKGG--QFRPEFLRISPNNKIPAIVDHSPADGGEPLSLFESGAILLYLAE 81 Query: 82 TRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQWA---------- 131 + L + ++RA G+ P+ +GQ + A Sbjct: 82 KTGL--FLSHETRERAATLQWLFWQVGGLGPM--------LGQNHHFNHAAPQTIPYAIE 131 Query: 132 --QKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDLSPYPTISHI 189 Q ++ L K L+++ + G+ S+AD+ P V R ++DL+ YP + + Sbjct: 132 RYQVETQRLYHVLNKRLENSP--WLGGENYSIADIACWPWVNAWTRQRIDLAMYPAVKNW 189 Query: 190 NKEL 193 ++ + Sbjct: 190 HERI 193 >5LCZ-A nrPDB Length = 222 Score = 47.4 bits (111), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 41/163 (25%), Positives = 78/163 (47%), Gaps = 7/163 (4%) Query: 3 AGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPAL 62 A KP L+ + R LA G+++E I +D + + + +QVP + Sbjct: 2 AEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMF---QQVPMV 58 Query: 63 KIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQV 122 +IDG+ +VQ+ AI+ Y+ L +D ++RA++ M S+ I + + L + Sbjct: 59 EIDGMKLVQTRAILNYIASKY---NLYGKDMKERALIDMYSEGILDLTEMIIQLVICPPD 115 Query: 123 GQENQMQWAQKVITSGF-NALEKILQSTAGKYCVGDEVSMADV 164 +E + A+ + + A EK+L+S Y VG+ ++ D+ Sbjct: 116 QREAKTALAKDRTKNRYLPAFEKVLKSHGQDYLVGNRLTRVDI 158 >2PMT-A nrPDB Length = 203 Score = 47.0 bits (110), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 47/189 (24%), Positives = 85/189 (44%), Gaps = 17/189 (8%) Query: 11 YFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKID-GITI 69 Y SCS I L G+D+ I I+L + + ++F +NP QVP L++D G + Sbjct: 5 YTPGSCSLSPHIVLRETGLDFSIERIDL-RTKKTESGKDFLAINPKGQVPVLQLDNGDIL 63 Query: 70 VQSLAIMEYLEETRPIPRLL--PQDPQKRAIVRMISDL---IASGIQPLQNLSVLKQVGQ 124 + +AI++YL + +P L+ P+ ++ + ++ L + G PL Sbjct: 64 TEGVAIVQYLADLKPDRNLIAPPKALERYHQIEWLNFLASEVHKGYSPL-----FSSDTP 118 Query: 125 ENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDLSPYP 184 E+ + + + S F + +L + K GD ++AD L A +DL+ Sbjct: 119 ESYLPVVKNKLKSKFVYINDVL--SKQKCVCGDHFTVADAYLFTLSQWAPHVALDLT--- 173 Query: 185 TISHINKEL 193 +SH+ L Sbjct: 174 DLSHLQDYL 182 >5LOL-A nrPDB Length = 215 Score = 46.6 bits (109), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 47/198 (23%), Positives = 92/198 (46%), Gaps = 30/198 (15%) Query: 19 RVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSLAIMEY 78 RV + L K + Y+ IN + D Q F + ++P +VP +K+DG + S I+ Sbjct: 27 RVLLTLEEKKLPYKTHLIN-VSDKPQWFLD----ISPEGKVPVVKLDGKWVADSDVIVGL 81 Query: 79 LEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQKVITSG 138 LEE P P L + P + A V S + + + L++ ++ ++K + Sbjct: 82 LEEKYPEPSL--KTPPEFASVG--SKIFGAFVTFLKS---------KDANDGSEKALVDE 128 Query: 139 FNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDLSPY---------PTISHI 189 ALE L++ +G + G++++ D+ L P++ + E V L Y ++ + Sbjct: 129 LEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLE---VALGHYKNWSVPESLTSVRNY 185 Query: 190 NKELLALEVFQVSHPRRQ 207 K L + E F+ + +++ Sbjct: 186 AKALFSRESFENTKAKKE 203 >3PR8-A nrPDB Length = 229 Score = 46.6 bits (109), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 45/172 (26%), Positives = 83/172 (48%), Gaps = 14/172 (8%) Query: 8 LYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGI 67 LY + S+ V++AL KG+ +E V GGQ + ++P +VP L+ + Sbjct: 5 LYGFSVSNYYNMVKLALLEKGLTFEEVTFY----GGQ--APQALEVSPRGKVPVLETEHG 58 Query: 68 TIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQ-PLQNLSVLKQVGQEN 126 + ++ I++Y+E+T+ LLP DP +A VR + I I+ P + G Sbjct: 59 FLSETSVILDYIEQTQGGKALLPADPFGQAKVRELLKEIELYIELPARTCYAESFFGMSV 118 Query: 127 Q---MQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADV--CLVPQVANA 173 + + A+ + +GF L++ Y G+++++AD+ C +ANA Sbjct: 119 EPLIKEKARADLLAGFATLKR--NGRFAPYVAGEQLTLADLMFCFSVDLANA 168 >3C8E-A nrPDB Length = 288 Score = 46.2 bits (108), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 43/163 (26%), Positives = 73/163 (44%), Gaps = 22/163 (13%) Query: 22 IALALKGIDYEIVPINLIKDG-GQQFTEEFQTLNPMKQVPALKIDG----ITIVQSLAIM 76 +AL + G +Y+ LI+ G G QF+ F +NP ++PAL+ I + +S +I+ Sbjct: 66 LALGVTGAEYDAW---LIRIGDGDQFSSGFVEVNPNSKIPALRDHTHNPPIRVFESGSIL 122 Query: 77 EYLEETRPIPRLLPQDPQKRA-------IVRMISDLIASGIQPLQNLSVLKQVGQENQMQ 129 YL E LPQD KR ++ + + G + + +K N+ Sbjct: 123 LYLAEK--FGYFLPQDLAKRTETMNWLFWLQGAAPFLGGGFGHFYHYAPVKIEYAINRFT 180 Query: 130 WAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVAN 172 K + + L+K L K+ GDE ++AD+ + P N Sbjct: 181 MEAKRL---LDVLDKQLAQH--KFVAGDEYTIADMAIWPWFGN 218 >5G5A-A nrPDB Length = 221 Score = 44.7 bits (104), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 44/169 (26%), Positives = 74/169 (43%), Gaps = 16/169 (9%) Query: 3 AGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPM-KQVPA 61 A + IL ++ S R RIAL K + ++ +L + +NP+ K++P Sbjct: 2 ADEVILLDFWPSMFGMRTRIALEEKNVKFDYREQDLWNK-----SPILLEMNPVHKKIPV 56 Query: 62 LKIDGITIVQSLAIMEYLEETRPIPR-LLPQDPQKRAIVRMISDLIASGIQPLQNLSVLK 120 L +G + +SL +EY++E P LLP DP +RA + D I + L + Sbjct: 57 LIHNGNPVCESLIQIEYIDEVWPSKTPLLPSDPYQRAQAKFWGDFIDKKVYASARL-IWG 115 Query: 121 QVGQENQMQWAQKVITSGFNALEKILQSTAGK--YCVGDEVSMADVCLV 167 G+E++ F + K L+S G Y G+ D+ L+ Sbjct: 116 AKGEEHEAG------KKEFIEILKTLESELGDKTYFGGETFGYVDIALI 158 >6EP7-A nrPDB Length = 220 Score = 44.7 bits (104), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 47/166 (28%), Positives = 74/166 (44%), Gaps = 18/166 (10%) Query: 7 ILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPM-KQVPALKID 65 IL Y+ S R RIAL K + YE +L + +NP+ K++P L + Sbjct: 6 ILLDYWASMYGMRTRIALEEKKVKYEYREEDL-----SNKSPLLLQMNPIHKKIPVLIHE 60 Query: 66 GITIVQSLAIMEYLEETRPIPR-LLPQDPQKRAIVRMISDLIASGIQ-PLQNLSVLKQVG 123 G I +S+ ++Y++E P +LP DP +RA R +D I P + L Sbjct: 61 GKPICESIIQVQYIDELWPDTNPILPSDPYQRAQARFWADYIDKKTYVPCKAL-----WS 115 Query: 124 QENQMQWAQKVITSGFNALEKILQSTAGK--YCVGDEVSMADVCLV 167 + + Q A K+ F + K L S G Y G+E + D+ + Sbjct: 116 ESGEKQEAAKI---EFIEVLKTLDSELGDKYYFGGNEFGLVDIAFI 158 >1AW9-A nrPDB Length = 216 Score = 44.7 bits (104), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 29/73 (39%), Positives = 41/73 (56%), Gaps = 4/73 (5%) Query: 8 LYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGI 67 LY S RV L KG+D+EIVP++L +Q +F LNP Q+PAL +DG Sbjct: 5 LYGMPLSPNVVRVATVLNEKGLDFEIVPVDLTTGAHKQ--PDFLALNPFGQIPAL-VDGD 61 Query: 68 TIV-QSLAIMEYL 79 ++ +S AI Y+ Sbjct: 62 EVLFESRAINRYI 74 >5A5K-A nrPDB Length = 212 Score = 44.7 bits (104), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 26/66 (39%), Positives = 39/66 (59%), Gaps = 2/66 (3%) Query: 14 SSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSL 73 S + RV IAL K +D+E+V + L KDG + E F + NP QVPA + + + +S Sbjct: 12 SIATRRVLIALHEKNLDFELVHVEL-KDGEHK-KEPFLSRNPFGQVPAFEDGDLKLFESR 69 Query: 74 AIMEYL 79 AI +Y+ Sbjct: 70 AITQYI 75 >4AGS-A nrPDB Length = 471 Score = 43.1 bits (100), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 41/169 (24%), Positives = 78/169 (46%), Gaps = 24/169 (14%) Query: 11 YFRSSCSW--RVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKI---D 65 Y ++C + RV I K + Y+ V + L ++ + ++ +NP + VP L++ D Sbjct: 30 YVSATCPFCHRVEIVAREKQVSYDRVAVGLR----EEMPQWYKQINPRETVPTLEVGNAD 85 Query: 66 GITIVQSLAIMEYLEET-RPIPRLLPQDPQKRAIVRM----ISDLIASGIQPLQN-LSVL 119 + +S+ I +YL+ + P L+ +R + + D I + L++ LS Sbjct: 86 KRFMFESMLIAQYLDNSGAPAGALMGSSAAQRHQIEFFLAQVGDFIGAAHGLLRDPLSGE 145 Query: 120 KQVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVP 168 K+ ++ + ++ + Q+T YC G E +MADV LVP Sbjct: 146 KRKAMDDNAAYVDGLLAAN--------QTTGPYYCDG-EFTMADVALVP 185 >2IL3-A nrPDB Length = 221 Score = 42.7 bits (99), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 46/175 (26%), Positives = 80/175 (45%), Gaps = 20/175 (11%) Query: 7 ILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDG 66 +LY+ S V + G++ E INL+ G EF LNP +P L +G Sbjct: 5 VLYTLHLSPPCRAVELTAKALGLELEQKTINLLT--GDHLKPEFVKLNPQHTIPVLDDNG 62 Query: 67 ITIVQSLAIMEYL-EETRPIPRLLPQDPQKRAIVRMISDL-IASGIQPLQNLSVLKQV-- 122 I +S AIM YL + L P+DP K+A R+ S L SG+ + + +++ Sbjct: 63 TIITESHAIMIYLVTKYGKDDSLYPKDPVKQA--RVNSALHFESGVLFARMRFIFERILF 120 Query: 123 -GQ----ENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVAN 172 G+ E+++++ QK + LE L + G +++AD + +++ Sbjct: 121 FGKSDIPEDRVEYVQK----SYELLEDTL---VDDFVAGPTMTIADFSCISTISS 168 >4MDC-A nrPDB Length = 252 Score = 42.7 bits (99), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 54/213 (25%), Positives = 91/213 (42%), Gaps = 23/213 (10%) Query: 6 PILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKID 65 P LY + S S VR+ L+ G E L ++ + +F TLNP +P D Sbjct: 24 PTLYHHPMSPASRFVRLILSEYGYQTE-----LSEEQPWENRRDFLTLNPAGTLPVYVDD 78 Query: 66 GI-TIVQSLAIMEYLEETRPI----PRLLPQDPQKRAIVRMISDLI-----ASGIQPLQN 115 + + + I EYL+ET I RLL +DP +RA +R +++ A +PL Sbjct: 79 SMRALCGATIISEYLDETSGIMKRDRRLLAEDPFQRAEIRRLTEWFLQKMEADVTRPLVR 138 Query: 116 LSVLKQVGQENQMQWA--QKVITSGFNALE---KILQSTAGK--YCVGDEVSMADVCLVP 168 + K +Q A K++ + + + K L AG + GD +S D+ Sbjct: 139 ERIFKLQMTPDQGGGAPDSKILRTSRSNIRQHMKYLSWLAGSRPWLAGDRISYGDLAAAA 198 Query: 169 QVANAERF-KVDLSPYPTISHINKELLALEVFQ 200 ++ + ++D S PT + L + F+ Sbjct: 199 AISVLDYLGEIDWSDAPTAKEWYQRLKSRPSFR 231 >1U3I-A nrPDB Length = 211 Score = 42.4 bits (98), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 49/221 (22%), Positives = 99/221 (44%), Gaps = 24/221 (10%) Query: 3 AGKPILYSYFRSSC-SWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPA 61 AG+ I YF + +R+ L G+DYE I+ Q + + P ++PA Sbjct: 2 AGEHIKVIYFDGRGRAESIRMTLVAAGVDYEDERISF------QDWPKIKPTIPGGRLPA 55 Query: 62 LKIDGIT-----IVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNL 116 +K+ +++SLAI Y+ + + + D + ++ ++I A ++ + Sbjct: 56 VKVTDDHGHVKWMLESLAIARYMAKKHHM--MGETDEEYYSVEKLIGQ--AEDVEHEYHK 111 Query: 117 SVLKQVGQENQMQWAQKVITSG----FNALEKILQSTAGKYCVGDEVSMADVCLVPQVAN 172 +++K QE + + ++++ FN + + L+ + GK VGD+V++AD+ L+ + + Sbjct: 112 TLMKP--QEEKEKITKEILNGKVPVLFNMICESLKGSTGKLAVGDKVTLADLVLIAVIDH 169 Query: 173 AERFKVDL--SPYPTISHINKELLALEVFQVSHPRRQPDTP 211 YP I + LLA + +P TP Sbjct: 170 VTDLDKGFLTGKYPEIHKHRENLLASSPRLAKYLSNRPATP 210 >4Q5F-A nrPDB Length = 218 Score = 42.4 bits (98), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 35/131 (26%), Positives = 54/131 (41%), Gaps = 18/131 (13%) Query: 54 NPMKQVPALKIDGITIVQSLAIMEYLEETRPIPRLLP-QDPQKRAIVRMISDLIA----- 107 P Q+P L++DG + QS AI YL + P ++ Q +I D +A Sbjct: 58 TPFGQLPLLEVDGEVLAQSAAIYRYLGRQFGLAGKTPMEEAQVDSIFDQFKDFMAELRPC 117 Query: 108 ----SGIQPLQNLSVLKQVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMAD 163 +G + VLK+V A LEK L + +Y VG V+ AD Sbjct: 118 FRVLAGFEEGDKEKVLKEV--------AVPARDKHLPLLEKFLAKSGSEYMVGKSVTWAD 169 Query: 164 VCLVPQVANAE 174 + + +A+ E Sbjct: 170 LVITDSLASWE 180 >4RI7-A nrPDB Length = 215 Score = 42.4 bits (98), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 23/61 (37%), Positives = 35/61 (57%), Gaps = 2/61 (3%) Query: 19 RVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSLAIMEY 78 RV L K + + ++PI+L K G+Q E+ + P QVPA K + IT+ +S AI Y Sbjct: 18 RVLATLIEKDVPFHLIPIDLSK--GEQKKPEYLKIQPFGQVPAFKDESITLFESRAICRY 75 Query: 79 L 79 + Sbjct: 76 I 76 >5IQY-A nrPDB Length = 216 Score = 42.4 bits (98), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 54/196 (27%), Positives = 85/196 (43%), Gaps = 26/196 (13%) Query: 19 RVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKI-DGITIVQSLAIME 77 RV + L K I YE+ ++L E F ++P +VP DG I S I + Sbjct: 28 RVLLTLEEKKITYEMKLVDL-----SNKPEWFLKISPEGKVPVFNSGDGKWIADSDVITQ 82 Query: 78 YLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQKVITS 137 +EE P P L+ P + A V S I P S +K + ++ ++K + Sbjct: 83 VIEEKFPTPSLV--TPPEYASV-------GSKIFP----SFVKFLKSKDASDGSEKALLD 129 Query: 138 GFNALEKILQSTAGKYCVGDEVSMADVCLVPQVAN----AERFKVDLSP--YPTISHINK 191 AL++ L++ G Y G+ VS AD+ L P++ + E FK P ++ K Sbjct: 130 ELQALDEHLKAH-GPYISGENVSAADLSLGPKLFHLQVALEHFKGWKIPENLTSVHAYTK 188 Query: 192 ELLALEVFQVSHPRRQ 207 L + E F + P Q Sbjct: 189 ALFSRESFVKTKPANQ 204 >5Y7I-A nrPDB Length = 261 Score = 42.0 bits (97), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 38/160 (23%), Positives = 71/160 (44%), Gaps = 14/160 (8%) Query: 19 RVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSLAIMEY 78 R+ + L LKG+ + + +++ K E + L P P L +G + I E+ Sbjct: 51 RLFMVLWLKGVKFTVTTVDMRKKPA-----ELKDLAPGTNPPFLLYNGTLKTDFIKIEEF 105 Query: 79 LEETRPIPRLLPQDPQKRAIVRMISDLIA--------SGIQPLQNLSVLKQVGQENQMQW 130 LE+T PR P + + +D+ A S PLQ ++L++ + + Sbjct: 106 LEQTLAPPRYPHLSPVNKESFDVGADIFAKFSAFIKNSPNNPLQEKNLLREFKRLDDYLN 165 Query: 131 AQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQV 170 + N++E I S K+ GD +++AD L+P++ Sbjct: 166 SPLPEEIDHNSVETITVSNR-KFLDGDRLTLADCNLLPKL 204 >2AAW-A nrPDB Length = 222 Score = 40.0 bits (92), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 46/203 (22%), Positives = 85/203 (41%), Gaps = 28/203 (13%) Query: 4 GKPILYSYFRSSCSWR-VRIALALKGIDYEIVPINLIKDGG---QQFTEEFQTLNPMKQV 59 G I+ YF + +R+ A GI+Y + D + F +E T P +QV Sbjct: 13 GDNIVLYYFDARGKAELIRLIFAYLGIEYTDKRFGVNGDAFVEFKNFKKEKDT--PFEQV 70 Query: 60 PALKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQ----N 115 P L+I + + QS AI+ YL + I + + +D+I G+Q + N Sbjct: 71 PILQIGDLILAQSQAIVRYLSKKYNI-------CGESELNEFYADMIFCGVQDIHYKFNN 123 Query: 116 LSVLKQVGQENQMQWAQKVITSGFNALEKILQSTAGK------YCVGDEVSMADVCLVPQ 169 ++ KQ N+ + + + EK+L+ Y VG+ ++ AD+ + Sbjct: 124 TNLFKQ----NETTFLNEDLPKWSGYFEKLLKKNHTNNNNDKYYFVGNNLTYADLAVFNL 179 Query: 170 VANAE-RFKVDLSPYPTISHINK 191 + E ++ L +P + N+ Sbjct: 180 YDDIETKYPSSLKNFPLLKAHNE 202 >4MPF-A nrPDB Length = 266 Score = 39.7 bits (91), Expect = 0.001, Method: Compositional matrix adjust. Identities = 39/146 (26%), Positives = 67/146 (45%), Gaps = 10/146 (6%) Query: 27 KGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSLAIMEYLEETRPIP 86 GI E+ ++L+K GQ ++EF +N + ++P LK + +S AI+ YL P Sbjct: 46 NGIPLELRTVDLVK--GQHKSKEFLQINSLGKLPTLKDGDFILTESSAILIYLSCKYQTP 103 Query: 87 -RLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQV-GQENQMQWAQKVITSGFNALEK 144 P D Q RA V A I+ + + QV G +Q ++ + A+++ Sbjct: 104 DHWYPSDLQARARVHEYLGWHADCIRGTFGIPLWVQVLGPLIGVQVPKEKVERNRTAMDQ 163 Query: 145 ILQSTAGK------YCVGDEVSMADV 164 LQ K + G +V++AD+ Sbjct: 164 ALQWLEDKFLGDRPFLAGQQVTLADL 189 >3R2Q-A nrPDB Length = 202 Score = 39.7 bits (91), Expect = 0.001, Method: Compositional matrix adjust. Identities = 48/169 (28%), Positives = 72/169 (42%), Gaps = 18/169 (10%) Query: 8 LYSYFRSSCSWRVRIALALKGIDYEIV---PINLIKDGGQQFTEEFQTLNPMKQVPALKI 64 L + S ++ I L KGI +E + P N +G QF NP+ +VP L Sbjct: 3 LVGSYTSPFVRKLSILLLEKGITFEFINELPYN-ADNGVAQF-------NPLGKVPVLVT 54 Query: 65 D-GITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVG 123 + G S I EY+E P +LP+DP + VR I L A GI +SV +Q Sbjct: 55 EEGECWFDSPIIAEYIELMNVAPAMLPRDPLESLRVRKIEAL-ADGIMDAGLVSVREQAR 113 Query: 124 -----QENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLV 167 E+++ ++ I + LE L K + ++A C V Sbjct: 114 PAAQQSEDELLRQREKINRSLDVLEGYLVDGTLKTDTVNLATIAIACAV 162 >3LSZ-A nrPDB Length = 225 Score = 39.3 bits (90), Expect = 0.001, Method: Compositional matrix adjust. Identities = 45/198 (22%), Positives = 86/198 (43%), Gaps = 24/198 (12%) Query: 8 LYSYFRSSCSWRVRIALALKGIDYEIVPI----NLIKDGGQQF-----TEEFQTLNPMKQ 58 +Y +RS S R LA + +E VP+ + G + + + +NP+ Q Sbjct: 5 IYGVYRSRAS-RPLWLLAELDLPFEHVPVIQANRVAHPHGPEAPLNTASAAYLAVNPLGQ 63 Query: 59 VPALKIDGITIVQSLAIMEYLEETRP---IPRLLPQDPQKRAIVRMISDLIASGIQ-PLQ 114 +P L+ +G+ + +SLAI ++ T+ PR P+D A++ S A+ ++ P Sbjct: 64 IPCLEEEGLILTESLAITLHIARTQGGQLGPRSEPED----ALMVSWSLFAATAVEPPAL 119 Query: 115 NLSVLKQVGQENQMQWAQKVITSGFNALEKIL-----QSTAGKYCVGDEVSMADVCLVPQ 169 + ++++ G + Q I L + L A Y VG ++AD+ L Sbjct: 120 EIQLIQRSGGGTSPE-GQAAIAIAAERLRRPLARLERHFAAEDYLVGGRFTVADLNLAET 178 Query: 170 VANAERFKVDLSPYPTIS 187 + + L P+P ++ Sbjct: 179 LRYGQAHPALLEPFPAVA 196 >5N9U-A nrPDB Length = 218 Score = 39.3 bits (90), Expect = 0.001, Method: Compositional matrix adjust. Identities = 44/156 (28%), Positives = 72/156 (46%), Gaps = 19/156 (12%) Query: 19 RVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSLAIMEY 78 RV ++L K I Y+ INL D Q F E ++P +VP +KID + S I+ Sbjct: 25 RVLLSLEEKKIPYKSHLINL-GDKPQWFLE----ISPEGKVPVVKIDDKWVADSDVIVGI 79 Query: 79 LEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQKVITSG 138 LEE P P L P + A V S I P S +K + ++ ++ + Sbjct: 80 LEEKNPEPPL--ATPPEFASV-------GSKIFP----SFVKFLKSKDPNDGTEQALLEE 126 Query: 139 FNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAE 174 AL+ L+ G + G++++ D+ L P++ + E Sbjct: 127 LKALDGHLK-VHGPFIAGEKITAVDLSLAPKLYHLE 161 >5NR1-A nrPDB Length = 228 Score = 37.4 bits (85), Expect = 0.005, Method: Compositional matrix adjust. Identities = 32/142 (22%), Positives = 60/142 (42%), Gaps = 16/142 (11%) Query: 49 EFQTLNPMKQVPAL----KIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISD 104 EF +LNP P L + I ++ AI+E++EET P LL +DP +RA R + Sbjct: 43 EFTSLNPSGMPPVLVETKHQRNLVICETRAILEHIEETETEPPLLGRDPAERAEARRLLQ 102 Query: 105 LIASGIQPLQNLSVLKQVGQEN----------QMQWAQKVITSGFNALEKILQSTAGKYC 154 N +L + ++ ++ ++ + +E +LQ+ + Sbjct: 103 WFDRKFDNEVNGFLLHEKMEKRLLRMGAPDLAALRQGREALRMHLGYIESLLQTR--DWL 160 Query: 155 VGDEVSMADVCLVPQVANAERF 176 G +S+AD ++ + F Sbjct: 161 AGRRMSLADFAAAAHLSVIDYF 182 >5F05-A nrPDB Length = 212 Score = 37.0 bits (84), Expect = 0.007, Method: Compositional matrix adjust. Identities = 25/73 (34%), Positives = 41/73 (56%), Gaps = 4/73 (5%) Query: 8 LYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDG- 66 L+ S+ + RV L K +++E+V +NL G+ E +LNP QVPA +DG Sbjct: 5 LHGSVLSTNTQRVLATLYEKEVEFELVNVNL--GAGEHKQEPHISLNPFGQVPA-AVDGD 61 Query: 67 ITIVQSLAIMEYL 79 + + +S AI +Y+ Sbjct: 62 LKLFESRAISQYV 74 >1OYJ-A nrPDB Length = 231 Score = 37.0 bits (84), Expect = 0.007, Method: Compositional matrix adjust. Identities = 27/86 (31%), Positives = 48/86 (55%), Gaps = 7/86 (8%) Query: 7 ILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPM-KQVPALKID 65 +L ++ S R RIA+A KG+++E +L G + ++ NP+ +++P L Sbjct: 8 VLLDFWVSPFGQRCRIAMAEKGLEFEYREEDL----GNK-SDLLLRSNPVHRKIPVLLHA 62 Query: 66 GITIVQSLAIMEYLEETRP-IPRLLP 90 G + +SL I++YL++ P P LLP Sbjct: 63 GRPVSESLVILQYLDDAFPGTPHLLP 88 >1N2A-A nrPDB Length = 201 Score = 35.8 bits (81), Expect = 0.016, Method: Compositional matrix adjust. Identities = 28/80 (35%), Positives = 46/80 (57%), Gaps = 2/80 (2%) Query: 11 YFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITIV 70 Y +CS I L G D+ +V ++L+K + + F +NP QVPAL +D T++ Sbjct: 5 YKPGACSLASHITLRESGKDFTLVSVDLMKKRLENGDDYF-AVNPKGQVPALLLDDGTLL 63 Query: 71 -QSLAIMEYLEETRPIPRLL 89 + +AIM+YL ++ P +LL Sbjct: 64 TEGVAIMQYLADSVPDRQLL 83 >1G6W-A nrPDB Length = 261 Score = 34.3 bits (77), Expect = 0.040, Method: Compositional matrix adjust. Identities = 22/75 (29%), Positives = 42/75 (56%), Gaps = 5/75 (6%) Query: 8 LYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPAL---KI 64 L+S+ + ++V I L+ G Y + ++ + G+ EF ++NP +VPAL + Sbjct: 23 LFSHRSAPNGFKVAIVLSELGFHYNTIFLDF--NLGEHRAPEFVSVNPNARVPALIDHGM 80 Query: 65 DGITIVQSLAIMEYL 79 D ++I +S AI+ +L Sbjct: 81 DNLSIWESGAILLHL 95 >3KXO-A nrPDB Length = 202 Score = 34.3 bits (77), Expect = 0.045, Method: Compositional matrix adjust. Identities = 36/152 (23%), Positives = 68/152 (44%), Gaps = 12/152 (7%) Query: 49 EFQTLNPMKQVPALKIDGITIVQSLAIMEYLEETRPIP-RLLPQDPQKRAIVRMISDLIA 107 E ++ P ++P L++DG+T+ QSLAI YL + + + AIV + D ++ Sbjct: 44 EIKSTLPFGKIPILEVDGLTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMS 103 Query: 108 SGIQPLQNLSVLKQVGQENQMQWAQKVITSGFNALEKILQSTAG--KYCVGDEVSMADVC 165 + V +Q+ E ++T L + L + G ++ +G+ V+ AD Sbjct: 104 CFPWAEKKQDVKEQMFNE--------LLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFY 155 Query: 166 LVPQVANAERFKVD-LSPYPTISHINKELLAL 196 FK D L +P + + K++ A+ Sbjct: 156 WEICSTTLLVFKPDLLDNHPRLVTLRKKVQAI 187 >2R5G-A nrPDB Length = 247 Score = 33.9 bits (76), Expect = 0.048, Method: Compositional matrix adjust. Identities = 34/161 (21%), Positives = 68/161 (42%), Gaps = 14/161 (8%) Query: 19 RVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSLAIMEY 78 R+ + L LKG+ + + +++ + EE + L P P L + + I E+ Sbjct: 35 RLFMILWLKGVKFNVTTVDMTRK-----PEELKDLAPGTNPPFLVYNKELKTDFIKIEEF 89 Query: 79 LEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQKVITSG 138 LE+T PR P+ + + +L A ++N E + K + Sbjct: 90 LEQTLAPPRYPHLSPKYKESFDVGCNLFAKFSAYIKNTQKEANKNFEKSLLKEFKRLDDY 149 Query: 139 FNA--LEKILQSTAGK-------YCVGDEVSMADVCLVPQV 170 N L++I +A + + GD++++AD L+P++ Sbjct: 150 LNTPLLDEIDPDSAEEPPVSRRLFLDGDQLTLADCSLLPKL 190 >1M0U-A nrPDB Length = 249 Score = 33.5 bits (75), Expect = 0.078, Method: Compositional matrix adjust. Identities = 35/150 (23%), Positives = 68/150 (45%), Gaps = 14/150 (9%) Query: 55 PMKQVPALKIDGITIVQSLAIMEYLEETRPIPRLLP-QDPQKRAIVRMISD----LIASG 109 PM Q+P L++DG + QS+++ +L +T + P +D Q +V I+D + Sbjct: 93 PMGQMPVLEVDGKRVHQSISMARFLAKTVGLCGATPWEDLQIDIVVDTINDFRLKIAVVS 152 Query: 110 IQPLQNLSVLKQVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCL--V 167 +P ++ ++ + +VI LE+ ++ G +G +++ ADV + Sbjct: 153 YEPED------EIKEKKLVTLNAEVIPFYLEKLEQTVKDNDGHLALG-KLTWADVYFAGI 205 Query: 168 PQVANAERFKVDLSPYPTISHINKELLALE 197 N + L PYP + + + ALE Sbjct: 206 TDYMNYMVKRDLLEPYPALRGVVDAVNALE 235 >3FY7-A nrPDB Length = 250 Score = 32.3 bits (72), Expect = 0.15, Method: Compositional matrix adjust. Identities = 38/164 (23%), Positives = 71/164 (43%), Gaps = 15/164 (9%) Query: 15 SCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSLA 74 SC R+ + L LKG VP L ++ + + P Q+P L D +L Sbjct: 44 SCQ-RLFMVLLLKG-----VPFTLTTVDTRRSPDVLKDFAPGSQLPILLYDSDAKTDTLQ 97 Query: 75 IMEYLEETRPIPRLLPQDPQKRA-------IVRMISDLIASGIQPLQNLSVLKQVGQE-N 126 I ++LEET P P+ R + S I + + P Q+ ++ +Q+ + Sbjct: 98 IEDFLEETLGPPDFPSLAPRYRESNTAGNDVFHKFSAFIKNPV-PAQDEALYQQLLRALA 156 Query: 127 QMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQV 170 ++ + A E L+ + ++ GD +++AD L+P++ Sbjct: 157 RLDSYLRAPLEHELAGEPQLRESRRRFLDGDRLTLADCSLLPKL 200 >5Y9Z-A nrPDB Length = 199 Score = 31.6 bits (70), Expect = 0.24, Method: Compositional matrix adjust. Identities = 25/111 (22%), Positives = 51/111 (45%), Gaps = 9/111 (8%) Query: 55 PMKQVPALKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQ 114 P ++P L+++G+T+ QSLAI YL + + K + + D + + Sbjct: 47 PFGKIPVLEVEGLTLHQSLAIARYLTKNTDL-------AGKTELEQCQVDAVVDTLDDFM 99 Query: 115 NLSVLKQVGQENQMQWAQKVITSGFNALEKILQSTAG--KYCVGDEVSMAD 163 +L + Q+ + + ++T L K L + G ++ +G+ V+ AD Sbjct: 100 SLFPWAEENQDLKERTFNDLLTRQAPHLLKDLDTYLGDKEWFIGNYVTWAD 150 >2CA8-A nrPDB Length = 211 Score = 31.6 bits (70), Expect = 0.26, Method: Compositional matrix adjust. Identities = 16/52 (30%), Positives = 28/52 (53%), Gaps = 2/52 (3%) Query: 146 LQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDL--SPYPTISHINKELLA 195 L+++ GK VGD+V++AD+ L+ + + + YP I + LLA Sbjct: 143 LKASTGKLAVGDKVTLADLVLIAVIDHVTDLDKEFLTGKYPEIHKHRENLLA 194 >3CLM-A nrPDB Length = 352 Score = 30.0 bits (66), Expect = 0.81, Method: Compositional matrix adjust. Identities = 16/36 (44%), Positives = 22/36 (61%), Gaps = 1/36 (2%) Query: 19 RVRIA-LALKGIDYEIVPINLIKDGGQQFTEEFQTL 53 R R+A +A GID E + L +DG +QF E F+ L Sbjct: 312 RARLAEIAALGIDVETLAARLQEDGLKQFEEAFEKL 347 >2FHE-A nrPDB Length = 216 Score = 29.6 bits (65), Expect = 0.90, Method: Compositional matrix adjust. Identities = 24/83 (28%), Positives = 40/83 (48%), Gaps = 4/83 (4%) Query: 20 VRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSLAIMEYL 79 VR+ L G YE I DG + F+++F+ + +P D + QSLAI+ Y+ Sbjct: 16 VRLLLEYLGEKYE-EQIYERDDGEKWFSKKFELGLDLPNLPYYIDDKCKLTQSLAILRYI 74 Query: 80 EETRPIPRLLPQDPQKRAIVRMI 102 + ++ ++RA V MI Sbjct: 75 ADKHG---MIGTTSEERARVSMI 94 >4GRS-A nrPDB Length = 333 Score = 29.6 bits (65), Expect = 1.1, Method: Compositional matrix adjust. Identities = 32/116 (27%), Positives = 54/116 (46%), Gaps = 12/116 (10%) Query: 92 DPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQ-ENQMQWAQKVITSGF-NALEKILQST 149 D + +V SD++ G + QN +LK+VG+ EN + ++ G N ++++L S Sbjct: 167 DTRHVELVAKYSDILQIGARNSQNFELLKEVGKVENPV-----LLKRGMGNTIQELLYSA 221 Query: 150 AGKYCVGDEVSMADVCLVPQVANAERFKVDLSPYPTISHINKELLALEVF-QVSHP 204 G+E + + A RF +D+S P + KEL L + SHP Sbjct: 222 EYIMAQGNENVILCERGIRTFETATRFTLDISAVPVV----KELSHLPIIVDPSHP 273 >2X7G-A nrPDB Length = 389 Score = 29.6 bits (65), Expect = 1.2, Method: Compositional matrix adjust. Identities = 15/53 (28%), Positives = 27/53 (50%), Gaps = 4/53 (7%) Query: 90 PQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQKVITSGFNAL 142 P DP K +V++I D SG+ + V + +G + ++W +I S + L Sbjct: 89 PSDPNKDMVVQLIDDFKISGMNGIHVCMVFEVLGH-HLLKW---IIKSNYQGL 137 >2HNL-A nrPDB Length = 225 Score = 28.1 bits (61), Expect = 3.2, Method: Compositional matrix adjust. Identities = 16/50 (32%), Positives = 29/50 (58%), Gaps = 2/50 (4%) Query: 143 EKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDLSPYPTI-SHINK 191 EK L+ + + VG++VS+AD+ + + + +V L YP + S +NK Sbjct: 158 EKFLKESTTGHIVGNKVSVADLTVFNMLMTLDD-EVKLEEYPQLASFVNK 206 >4C1L-A nrPDB Length = 262 Score = 27.7 bits (60), Expect = 3.5, Method: Compositional matrix adjust. Identities = 32/116 (27%), Positives = 53/116 (45%), Gaps = 12/116 (10%) Query: 92 DPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQ-ENQMQWAQKVITSGF-NALEKILQST 149 D + +V SD++ G + QN +LK+VG+ EN + ++ G N ++++L S Sbjct: 96 DTRHVELVAKYSDILQIGARNSQNFELLKEVGKVENPV-----LLKRGMGNTIQELLYSA 150 Query: 150 AGKYCVGDEVSMADVCLVPQVANAERFKVDLSPYPTISHINKELLALEVF-QVSHP 204 G+E + + A RF +D S P + KEL L + SHP Sbjct: 151 EYIMAQGNENVILCERGIRTFETATRFTLDDSAVPVV----KELSHLPIIVDPSHP 202 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2CZ2-A nrPDB 310 3e-85 1FW1-A nrPDB 298 1e-81 1E6B-A nrPDB 217 2e-57 4IGJ-A nrPDB 201 2e-52 3NIV-A nrPDB 199 6e-52 3LG6-A nrPDB 196 6e-51 2JL4-A nrPDB 191 1e-49 4PXO-A nrPDB 182 1e-46 3I6A-A nrPDB 181 2e-46 6JWK-A nrPDB 175 1e-44 2VCV-A nrPDB 173 5e-44 1PL2-A nrPDB 169 7e-43 2VCT-A nrPDB 168 1e-42 1F3B-A nrPDB 167 3e-42 4PNG-A nrPDB 163 5e-41 1VF1-A nrPDB 160 3e-40 5LCZ-A nrPDB 160 3e-40 1JLV-A nrPDB 159 1e-39 4YH2-A nrPDB 159 1e-39 1PN9-A nrPDB 157 2e-39 3VWX-A nrPDB 156 6e-39 5J5N-A nrPDB 155 2e-38 4J2F-A nrPDB 155 2e-38 2VO4-A nrPDB 154 3e-38 4CHS-A nrPDB 153 6e-38 1B48-A nrPDB 153 6e-38 3MAK-A nrPDB 151 2e-37 3M3M-A nrPDB 150 3e-37 5ZWP-A nrPDB 149 8e-37 1EV4-A nrPDB 149 1e-36 4QQ7-A nrPDB 147 4e-36 5ECL-B nrPDB 146 6e-36 5F06-A nrPDB 146 8e-36 5F0G-A nrPDB 145 1e-35 5G5A-A nrPDB 145 1e-35 3UAR-A nrPDB 144 2e-35 1GUL-A nrPDB 144 3e-35 3QAG-A nrPDB 143 7e-35 3GH6-A nrPDB 143 7e-35 3M8N-A nrPDB 142 1e-34 2GDR-A nrPDB 142 2e-34 5ELG-A nrPDB 140 3e-34 3LFL-A nrPDB 140 6e-34 5F07-A nrPDB 139 7e-34 6EP7-A nrPDB 139 1e-33 5LOL-A nrPDB 136 7e-33 4MDC-A nrPDB 135 1e-32 5IQY-A nrPDB 135 1e-32 2IL3-A nrPDB 135 2e-32 3GX0-A nrPDB 134 3e-32 1AXD-A nrPDB 128 1e-30 1AW9-A nrPDB 128 1e-30 1F2E-A nrPDB 127 3e-30 2PMT-A nrPDB 127 3e-30 3TOT-A nrPDB 126 7e-30 3WD6-A nrPDB 125 9e-30 6F05-A nrPDB 124 2e-29 3LSZ-A nrPDB 123 4e-29 5N9U-A nrPDB 123 8e-29 4MK3-A nrPDB 122 1e-28 3IBH-A nrPDB 122 1e-28 4RI7-A nrPDB 121 2e-28 1U3I-A nrPDB 121 3e-28 1V2A-A nrPDB 120 4e-28 1GWC-A nrPDB 120 7e-28 4PQI-A nrPDB 119 1e-27 1YQ1-A nrPDB 118 1e-27 3UBL-A nrPDB 117 4e-27 5A5K-A nrPDB 115 1e-26 4MPF-A nrPDB 114 4e-26 2AAW-A nrPDB 113 4e-26 3R2Q-A nrPDB 113 6e-26 3PR8-A nrPDB 112 2e-25 3C8E-A nrPDB 108 2e-24 5Y7I-A nrPDB 108 2e-24 4Q5F-A nrPDB 105 2e-23 4AGS-A nrPDB 104 3e-23 2C3Q-A nrPDB 103 7e-23 3BBY-A nrPDB 97 4e-21 Sequences not found previously or not previously below threshold: 5D9W-A nrPDB 130 6e-31 5EY6-A nrPDB 130 6e-31 2CA8-A nrPDB 110 6e-25 5NR1-A nrPDB 109 1e-24 5F05-A nrPDB 107 4e-24 3RBT-A nrPDB 106 7e-24 1N2A-A nrPDB 102 2e-22 1G6W-A nrPDB 100 4e-22 1ZL9-A nrPDB 97 4e-21 4IKH-A nrPDB 97 8e-21 2PVQ-A nrPDB 96 1e-20 1GSQ-A nrPDB 92 2e-19 2R5G-A nrPDB 91 3e-19 1OYJ-A nrPDB 91 4e-19 5F8B-A nrPDB 87 5e-18 3FY7-A nrPDB 87 5e-18 3KXO-A nrPDB 84 3e-17 4Q5R-A nrPDB 83 8e-17 2WDU-A nrPDB 82 3e-16 5D73-A nrPDB 81 3e-16 2GLR-A nrPDB 80 5e-16 5Y9Z-A nrPDB 80 8e-16 4K0G-A nrPDB 79 1e-15 18GS-A nrPDB 79 2e-15 2D2Z-A nrPDB 78 3e-15 1M0U-A nrPDB 77 7e-15 2GSR-A nrPDB 76 1e-14 1TU7-A nrPDB 75 2e-14 2HNL-A nrPDB 74 3e-14 5AN1-A nrPDB 74 5e-14 2DC5-A nrPDB 74 6e-14 2FHE-A nrPDB 73 9e-14 5FWG-A nrPDB 70 5e-13 1B4P-A nrPDB 70 9e-13 1XWK-A nrPDB 69 1e-12 4Q5Q-A nrPDB 69 1e-12 1HNA-A nrPDB 69 2e-12 4GTU-A nrPDB 65 2e-11 4FQU-A nrPDB 65 2e-11 2WRT-A nrPDB 63 9e-11 3PPU-A nrPDB 63 1e-10 1FHE-A nrPDB 63 1e-10 3GTU-B nrPDB 62 1e-10 1B8X-A nrPDB 62 2e-10 1BG5-A nrPDB 62 2e-10 1DUG-A nrPDB 62 2e-10 3IR4-A nrPDB 57 5e-09 1GSU-A nrPDB 57 6e-09 4LMW-A nrPDB 56 9e-09 6GC9-A nrPDB 56 1e-08 1G7O-A nrPDB 55 3e-08 6GCB-A nrPDB 55 3e-08 4WR5-A nrPDB 54 5e-08 4BVY-B nrPDB 53 7e-08 2YV7-A nrPDB 53 1e-07 6GZF-A nrPDB 52 2e-07 3M1G-A nrPDB 48 2e-06 4G0L-A nrPDB 47 5e-06 4PTS-A nrPDB 46 2e-05 4LMV-A nrPDB 43 1e-04 4USS-A nrPDB 42 2e-04 5LKB-A nrPDB 42 3e-04 5CAX-A nrPDB 41 3e-04 2YV9-A nrPDB 40 0.001 4LA1-A nrPDB 38 0.003 2PBJ-A nrPDB 38 0.004 2JZR-A nrPDB 37 0.007 2X8H-A nrPDB 37 0.008 3GRX-A nrPDB 37 0.009 3QMX-A nrPDB 35 0.020 2H30-A nrPDB 35 0.021 3IC4-A nrPDB 35 0.024 3NZN-A nrPDB 35 0.027 2MYG-A nrPDB 35 0.031 5MB9-A nrPDB 32 0.17 2MZC-A nrPDB 31 0.39 2KLX-A nrPDB 31 0.46 1NM3-A nrPDB 31 0.52 3D3U-A nrPDB 30 0.71 2IUJ-A nrPDB 30 0.93 3RHC-A nrPDB 29 1.5 1THX-A nrPDB 29 1.7 3ZZN-A nrPDB 29 1.7 4K38-A nrPDB 28 2.6 1YMG-A nrPDB 28 2.6 4R0M-B nrPDB 28 4.6 1HX8-A nrPDB 27 5.5 4QKU-A nrPDB 27 5.9 3WDK-A nrPDB 27 7.0 5TI1-A nrPDB 27 8.9 >2CZ2-A nrPDB Length = 223 Score = 310 bits (795), Expect = 3e-85, Method: Composition-based stats. Identities = 216/216 (100%), Positives = 216/216 (100%) Query: 1 MQAGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVP 60 MQAGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVP Sbjct: 8 MQAGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVP 67 Query: 61 ALKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLK 120 ALKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLK Sbjct: 68 ALKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLK 127 Query: 121 QVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDL 180 QVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDL Sbjct: 128 QVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDL 187 Query: 181 SPYPTISHINKELLALEVFQVSHPRRQPDTPAELRT 216 SPYPTISHINKELLALEVFQVSHPRRQPDTPAELRT Sbjct: 188 SPYPTISHINKELLALEVFQVSHPRRQPDTPAELRT 223 >1FW1-A nrPDB Length = 216 Score = 298 bits (763), Expect = 1e-81, Method: Composition-based stats. Identities = 184/215 (85%), Positives = 196/215 (91%) Query: 1 MQAGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVP 60 MQAGKPILYSYFRSSCSWRVRIALALKGIDY+ VPINLIKDGGQQF+++FQ LNPMKQVP Sbjct: 1 MQAGKPILYSYFRSSCSWRVRIALALKGIDYKTVPINLIKDGGQQFSKDFQALNPMKQVP 60 Query: 61 ALKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLK 120 LKIDGITI QSLAI+EYLEETRP PRLLPQDP+KRA VRMISDLIA GIQPLQNLSVLK Sbjct: 61 TLKIDGITIHQSLAIIEYLEETRPTPRLLPQDPKKRASVRMISDLIAGGIQPLQNLSVLK 120 Query: 121 QVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDL 180 QVG+E Q+ WAQ IT GFNALE+ILQSTAG YCVGDEV+MAD+CLVPQVANAERFKVDL Sbjct: 121 QVGEEMQLTWAQNAITCGFNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAERFKVDL 180 Query: 181 SPYPTISHINKELLALEVFQVSHPRRQPDTPAELR 215 +PYPTIS INK LL LE FQVSHP RQPDTP ELR Sbjct: 181 TPYPTISSINKRLLVLEAFQVSHPCRQPDTPTELR 215 >1E6B-A nrPDB Length = 221 Score = 217 bits (554), Expect = 2e-57, Method: Composition-based stats. Identities = 99/214 (46%), Positives = 138/214 (64%), Gaps = 7/214 (3%) Query: 4 GKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALK 63 K LYSY+RSSC+ RVRIALALKG+DYE +P+NL+K G QF +F+ +NPM VPAL Sbjct: 7 EKLKLYSYWRSSCAHRVRIALALKGLDYEYIPVNLLK--GDQFDSDFKKINPMGTVPALV 64 Query: 64 IDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVG 123 + I S AI+ YL+E P P LLP+D KRA+ ++ SGIQP QNL+V++ + Sbjct: 65 DGDVVINDSFAIIMYLDEKYPEPPLLPRDLHKRAVNYQAMSIVLSGIQPHQNLAVIRYIE 124 Query: 124 Q----ENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANA-ERFKV 178 + E + W IT GF ALEK+L + AGK+ GDE+ +AD+ L PQ+ A RF++ Sbjct: 125 EKINVEEKTAWVNNAITKGFTALEKLLVNCAGKHATGDEIYLADLFLAPQIHGAINRFQI 184 Query: 179 DLSPYPTISHINKELLALEVFQVSHPRRQPDTPA 212 ++ PYPT++ + L FQ + P +QPD P+ Sbjct: 185 NMEPYPTLAKCYESYNELPAFQNALPEKQPDAPS 218 >4IGJ-A nrPDB Length = 242 Score = 201 bits (510), Expect = 2e-52, Method: Composition-based stats. Identities = 98/217 (45%), Positives = 137/217 (63%), Gaps = 9/217 (4%) Query: 2 QAGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPA 61 Q+ LYSY+RSS +WRVR+ LALKG+ YE ++L+ +QF Q NPM QVP Sbjct: 21 QSMTLRLYSYWRSSSAWRVRLGLALKGLAYEYRAVDLLAQ--EQFQAAHQARNPMSQVPV 78 Query: 62 LKI--DGIT--IVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLS 117 L++ DG T +VQS+AI+E+LEE P P LLP D RA VR +++ + SG QP+QN Sbjct: 79 LEVEEDGRTHLLVQSMAILEWLEERHPEPALLPPDLWGRARVRALAEHVNSGTQPMQNAL 138 Query: 118 VLKQVGQE---NQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAE 174 VL+ + ++ +WA+ I G ALE ++ AG++ GD ++AD LVPQ+ NA Sbjct: 139 VLRMLREKVPGWDREWARFFIARGLAALETAVRDGAGRFSHGDAPTLADCYLVPQLYNAR 198 Query: 175 RFKVDLSPYPTISHINKELLALEVFQVSHPRRQPDTP 211 RF +DL PYPT+ +++ AL FQ +HP RQPD P Sbjct: 199 RFGLDLEPYPTLRRVDEACAALAPFQAAHPDRQPDAP 235 >3NIV-A nrPDB Length = 222 Score = 199 bits (507), Expect = 6e-52, Method: Composition-based stats. Identities = 84/208 (40%), Positives = 129/208 (62%), Gaps = 8/208 (3%) Query: 6 PILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKID 65 ILY YFRS+ +RVRIAL LK I YE + ++L+ +GG+Q + ++ +NP + VP+L I+ Sbjct: 3 LILYDYFRSTACYRVRIALNLKKIAYEKIEVHLVNNGGEQHSLQYHQINPQELVPSLDIN 62 Query: 66 GITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVG-- 123 G + QS+AI++YLEE P LLP+DP +A ++ ++ ++A + PL NL VL ++ Sbjct: 63 GQILSQSMAIIDYLEEIHPEMPLLPKDPFMKATLKSMALIVACDMHPLNNLRVLNRLKEQ 122 Query: 124 ----QENQMQWAQKVITSGFNALEKILQS--TAGKYCVGDEVSMADVCLVPQVANAERFK 177 +E ++W + +GF+A E+ L + C G EV +ADVCL+PQV NA RF Sbjct: 123 FNANEEQVLEWYHHWLKTGFDAFEEKLGALERDKPVCFGSEVGLADVCLIPQVYNAHRFH 182 Query: 178 VDLSPYPTISHINKELLALEVFQVSHPR 205 D++ YP I+ IN+ L L F + P Sbjct: 183 FDMASYPIINEINEYCLTLPAFHDAAPE 210 >3LG6-A nrPDB Length = 235 Score = 196 bits (499), Expect = 6e-51, Method: Composition-based stats. Identities = 97/225 (43%), Positives = 139/225 (61%), Gaps = 19/225 (8%) Query: 8 LYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKID-- 65 LY YFRSSCS R+RIA LK I Y P+NL+K G+Q ++ +++LNP VP L + Sbjct: 12 LYGYFRSSCSGRLRIAFHLKSIPYTRHPVNLLK--GEQHSDTYKSLNPTNTVPLLVVSNI 69 Query: 66 ---------GITIVQSLAIMEYLEETRPI--PRLLP--QDPQKRAIVRMISDLIASGIQP 112 +I QSLA +EYLEE P LLP +P RA VR I ++IA +QP Sbjct: 70 NNTVSPSSASFSIGQSLAALEYLEEALPTNARPLLPPISNPVARAHVRTICNIIACDVQP 129 Query: 113 LQNLSVLKQVGQEN--QMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQV 170 + NL + K+V + W++ + T GF A+EK+L+ +AG++CVGDE+++ADVCLVP V Sbjct: 130 VTNLKIQKKVKALDGDPTVWSRDLATQGFGAVEKLLELSAGRFCVGDEITLADVCLVPAV 189 Query: 171 ANAERFKVDLSPYPTISHINKELLALEVFQVSHPRRQPDTPAELR 215 AER +DL+ +P + +E+L E Q +H ++Q DTP +LR Sbjct: 190 WAAERVGMDLARFPITKRVFEEMLKEEAVQKAHWQKQEDTPEDLR 234 >2JL4-A nrPDB Length = 213 Score = 191 bits (486), Expect = 1e-49, Method: Composition-based stats. Identities = 83/214 (38%), Positives = 123/214 (57%), Gaps = 10/214 (4%) Query: 5 KPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKI 64 K LY+++RS S R+RIAL LKG+ YE + ++L K+ + + F+ LNP + VPAL Sbjct: 1 KMKLYNFWRSGTSHRLRIALNLKGVPYEYLAVHLGKE--EHLKDAFKALNPQQLVPALDT 58 Query: 65 DGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVL----K 120 ++QS AI+E+LEE P P LLP D R VR ++ ++ I P+ N +L K Sbjct: 59 GAQVLIQSPAIIEWLEEQYPTPALLPADADGRQRVRALAAIVGCDIHPINNRRILEYLRK 118 Query: 121 QVGQENQM--QWAQKVITSGFNALEKIL--QSTAGKYCVGDEVSMADVCLVPQVANAERF 176 G + W I++GF+A E +L G+Y GD ++AD LVPQV +A RF Sbjct: 119 TFGADEAAINAWCGTWISAGFDAYEALLAVDPKRGRYSFGDTPTLADCYLVPQVESARRF 178 Query: 177 KVDLSPYPTISHINKELLALEVFQVSHPRRQPDT 210 +VDL+PYP I ++ L+ F+ + P QPD+ Sbjct: 179 QVDLTPYPLIRAVDAACGELDAFRRAAPAAQPDS 212 >4PXO-A nrPDB Length = 238 Score = 182 bits (462), Expect = 1e-46, Method: Composition-based stats. Identities = 84/216 (38%), Positives = 123/216 (56%), Gaps = 11/216 (5%) Query: 6 PILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKI- 64 +Y +RS+ ++RVRIAL LKGI YE V ++L D G Q +F +NP VPAL Sbjct: 24 VKMYGNWRSAAAFRVRIALNLKGIAYEEVFLDL--DAGDQHKPDFLAINPQGAVPALFDG 81 Query: 65 DGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQ 124 DG + QSLAI++YLEETR LLP++P+ RA R ++ ++A PL V + + Sbjct: 82 DGPPLTQSLAILDYLEETRTGVPLLPEEPRARARARSLAQVVACDTHPLYVPRVRTFLME 141 Query: 125 ------ENQMQWAQKVITSGFNALEKILQSTAG--KYCVGDEVSMADVCLVPQVANAERF 176 E +++ + +G LE L + AG ++C GD VS AD+CL+ F Sbjct: 142 NYGLPRERMLEFLRNAFITGLKTLETRLSNEAGTGRFCQGDAVSHADLCLISLWVGTGIF 201 Query: 177 KVDLSPYPTISHINKELLALEVFQVSHPRRQPDTPA 212 +D + YPT+ I++E+LAL+ +HP RQP PA Sbjct: 202 GIDTAAYPTVKRISEEVLALDAVARAHPLRQPGAPA 237 >3I6A-A nrPDB Length = 222 Score = 181 bits (460), Expect = 2e-46, Method: Composition-based stats. Identities = 56/220 (25%), Positives = 100/220 (45%), Gaps = 12/220 (5%) Query: 3 AGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPAL 62 A KP L+ + R LA G+++E I +D + + + +QVP + Sbjct: 2 AEKPKLHYFNGRGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLM---FQQVPMV 58 Query: 63 KIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQV 122 +IDG+ +VQ+ AI+ Y+ L +D ++RA++ M + IA + + L Sbjct: 59 EIDGMKLVQTRAILNYIASKY---NLYGKDIKERALIDMYIEGIADLGEMIIMLPFCPPE 115 Query: 123 GQENQMQWAQKVIT-SGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDL- 180 ++ ++ ++ I F A EK+L+S Y VG+++S AD+ LV + E L Sbjct: 116 EKDAKLALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLI 175 Query: 181 SPYPTISHINKELLALE----VFQVSHPRRQPDTPAELRT 216 S +P + + + L Q PR+ P +RT Sbjct: 176 SSFPLLKALKTRISNLPTVKKFLQPGSPRKPPPDEIYVRT 215 >6JWK-A nrPDB Length = 222 Score = 175 bits (444), Expect = 1e-44, Method: Composition-based stats. Identities = 91/210 (43%), Positives = 125/210 (59%), Gaps = 10/210 (4%) Query: 8 LYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKI-DG 66 LYS+F SS S+RVRIALALKG+DY++VP+NL + G+Q + NPM +P L DG Sbjct: 3 LYSFFNSSTSYRVRIALALKGLDYQVVPVNLRQ--GEQLRPADRQRNPMGALPTLVDADG 60 Query: 67 ITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQ-- 124 QSLAI++YL+ +P PRL+P DP RA ++ L+A I PL N+ VLK + Q Sbjct: 61 RRFSQSLAIIDYLDAVQPEPRLIPLDPLHRAQALELALLVACDIHPLNNVRVLKYLTQVL 120 Query: 125 ----ENQMQWAQKVITSGFNALEKIL-QSTAGKYCVGDEVSMADVCLVPQVANAERFKVD 179 E++ +W + G A E +L + G + G + + CLVPQ+ANA R D Sbjct: 121 GIDAEDRQRWYAHWVAEGLAAAETLLNRHRRGAFFAGAAAGIVECCLVPQLANARRMGCD 180 Query: 180 LSPYPTISHINKELLALEVFQVSHPRRQPD 209 L+PYP + + LALE FQ + P RQPD Sbjct: 181 LAPYPALLELEGRCLALEAFQRASPERQPD 210 >2VCV-A nrPDB Length = 222 Score = 173 bits (439), Expect = 5e-44, Method: Composition-based stats. Identities = 55/214 (25%), Positives = 101/214 (47%), Gaps = 12/214 (5%) Query: 3 AGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPAL 62 AGKP L+ + +R LA G+++E I +D G+ + +QVP + Sbjct: 2 AGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLM---FQQVPMV 58 Query: 63 KIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQV 122 +IDG+ +VQ+ AI+ Y+ L +D ++RA++ M ++ +A + + L + + Sbjct: 59 EIDGMKLVQTRAILNYIASKY---NLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPE 115 Query: 123 GQENQMQWAQKVIT-SGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDL- 180 ++ ++ ++ F A EK+LQS Y VG+++S AD+ LV + E L Sbjct: 116 EKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLI 175 Query: 181 SPYPTISHINKELLALE----VFQVSHPRRQPDT 210 S +P + + + L Q PR+ P Sbjct: 176 SNFPLLKALKTRISNLPTVKKFLQPGSPRKPPAD 209 >1PL2-A nrPDB Length = 222 Score = 169 bits (429), Expect = 7e-43, Method: Composition-based stats. Identities = 56/218 (25%), Positives = 98/218 (44%), Gaps = 12/218 (5%) Query: 3 AGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPAL 62 A KP L+ + R LA G+++E I +D + + + +QVP + Sbjct: 2 AEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLM---FQQVPMV 58 Query: 63 KIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQV 122 +IDG+ +VQ AI+ Y+ L +D ++RA++ M + IA + + L V Sbjct: 59 EIDGMKLVQERAILNYIASKY---NLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPE 115 Query: 123 GQENQMQWAQKVIT-SGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDL- 180 ++ ++ ++ I F A EK+L+S Y VG+++S AD+ LV + E L Sbjct: 116 EKDAKLALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLI 175 Query: 181 SPYPTISHINKELLALE----VFQVSHPRRQPDTPAEL 214 S +P + + + L Q PR+ P L Sbjct: 176 SSFPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSL 213 >2VCT-A nrPDB Length = 222 Score = 168 bits (426), Expect = 1e-42, Method: Composition-based stats. Identities = 55/218 (25%), Positives = 98/218 (44%), Gaps = 12/218 (5%) Query: 3 AGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPAL 62 A KP L+ +R LA G+++E I +D + + + +QVP + Sbjct: 2 AEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLM---FQQVPMV 58 Query: 63 KIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQV 122 +IDG+ +VQ+ AI+ Y+ L +D +++A++ M + IA + + L + Sbjct: 59 EIDGMKLVQTRAILNYIASKY---NLYGKDIKEKALIDMYIEGIADLGEMILLLPFTQPE 115 Query: 123 GQENQMQWAQKVIT-SGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDL- 180 Q+ ++ Q+ F A EK+L+S Y VG+++S AD+ LV + E L Sbjct: 116 EQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLI 175 Query: 181 SPYPTISHINKELLALE----VFQVSHPRRQPDTPAEL 214 S +P + + + L Q PR+ P L Sbjct: 176 SSFPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSL 213 >1F3B-A nrPDB Length = 222 Score = 167 bits (423), Expect = 3e-42, Method: Composition-based stats. Identities = 51/219 (23%), Positives = 97/219 (44%), Gaps = 12/219 (5%) Query: 3 AGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPAL 62 AGKP+L+ + +R LA G+++E I +D + + QVP + Sbjct: 1 AGKPVLHYFNARGRMECIRWLLAAAGVEFEEKFIQSPEDLEKLKKDGNLM---FDQVPMV 57 Query: 63 KIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQV 122 +IDG+ + Q+ AI+ Y+ L +D ++RA++ M S+ I + + L + Sbjct: 58 EIDGMKLAQTRAILNYIATKYD---LYGKDMKERALIDMYSEGILDLTEMIGQLVLCPPD 114 Query: 123 GQENQMQWAQKVIT-SGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVD-L 180 +E + A+ A EK+L+S Y VG+ ++ D+ L+ + E F L Sbjct: 115 QREAKTALAKDRTKNRYLPAFEKVLKSHGQDYLVGNRLTRVDIHLLEVLLYVEEFDASLL 174 Query: 181 SPYPTISHINKELLALE----VFQVSHPRRQPDTPAELR 215 +P+P + + +L Q R+ P +++ Sbjct: 175 TPFPLLKAFKSRISSLPNVKKFLQPGSQRKPPMDAKQIQ 213 >4PNG-A nrPDB Length = 229 Score = 163 bits (413), Expect = 5e-41, Method: Composition-based stats. Identities = 60/203 (29%), Positives = 91/203 (44%), Gaps = 9/203 (4%) Query: 5 KPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKI 64 K ILY S V++ LA + YE V +N + F+EEF NP VP L+ Sbjct: 9 KLILYGLEASPPVRAVKLTLAALEVPYEFVEVN--TRAKENFSEEFLKKNPQHTVPTLED 66 Query: 65 DGITIVQSLAIMEYLEETRP-IPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVG 123 DG I S AI+ YL L P+D +RA+V + I S+ K + Sbjct: 67 DGHYIWDSHAIIAYLVSKYGKTDSLYPKDLLQRAVVDQRLHFESGVIFANALRSITKPLF 126 Query: 124 QENQM---QWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERF-KVD 179 Q + I ++ LEK L Y G+++++AD ++ V++ E F KVD Sbjct: 127 AGKQTMIPKERYDAIIEVYDFLEKFL--AGNDYVAGNQLTIADFSIISTVSSLEVFVKVD 184 Query: 180 LSPYPTISHINKELLALEVFQVS 202 + YP I+ K L L ++ + Sbjct: 185 TTKYPRIAAWFKRLQKLPYYEEA 207 >1VF1-A nrPDB Length = 229 Score = 160 bits (406), Expect = 3e-40, Method: Composition-based stats. Identities = 52/211 (24%), Positives = 95/211 (45%), Gaps = 11/211 (5%) Query: 3 AGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPAL 62 A KP+LY + +R LA G+++E V + + + +QVP + Sbjct: 2 AAKPVLYYFNGRGKMESIRWLLAAAGVEFEEVFLETREQYEKLLQSGILM---FQQVPMV 58 Query: 63 KIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQV 122 +IDG+ +VQ+ AI+ Y+ L +D ++RA++ M + L + L Sbjct: 59 EIDGMKLVQTRAILNYIAGKY---NLYGKDLKERALIDMYVGGTDDLMGFLLSFPFLSAE 115 Query: 123 GQENQMQWA-QKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVD-L 180 + Q + +K + F A EK+L+ + VG+ +S AD+ L+ + E K D L Sbjct: 116 DKVKQCAFVVEKATSRYFPAYEKVLKDHGQDFLVGNRLSWADIHLLEAILMVEEKKSDAL 175 Query: 181 SPYPTISHINKELLALE---VFQVSHPRRQP 208 S +P + K + ++ F +R+P Sbjct: 176 SGFPLLQAFKKRISSIPTIKKFLAPGSKRKP 206 >5LCZ-A nrPDB Length = 222 Score = 160 bits (406), Expect = 3e-40, Method: Composition-based stats. Identities = 50/212 (23%), Positives = 94/212 (44%), Gaps = 11/212 (5%) Query: 3 AGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPAL 62 A KP L+ + R LA G+++E I +D + + + +QVP + Sbjct: 2 AEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLM---FQQVPMV 58 Query: 63 KIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQV 122 +IDG+ +VQ+ AI+ Y+ L +D ++RA++ M S+ I + + L + Sbjct: 59 EIDGMKLVQTRAILNYIASKY---NLYGKDMKERALIDMYSEGILDLTEMIIQLVICPPD 115 Query: 123 GQENQMQWAQKVIT-SGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVD-L 180 +E + A+ A EK+L+S Y VG+ ++ D+ L+ + E F L Sbjct: 116 QREAKTALAKDRTKNRYLPAFEKVLKSHGQDYLVGNRLTRVDIHLLELLLYVEEFDASLL 175 Query: 181 SPYPTISHINKELLALE---VFQVSHPRRQPD 209 + +P + + +L F +R+P Sbjct: 176 TSFPLLKAFKSRISSLPNVKKFLQPGSQRKPA 207 >1JLV-A nrPDB Length = 209 Score = 159 bits (402), Expect = 1e-39, Method: Composition-based stats. Identities = 46/187 (24%), Positives = 85/187 (45%), Gaps = 8/187 (4%) Query: 9 YSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGIT 68 Y S+ V++ A G++ + NL+ G+ EF +NP +P L +G Sbjct: 4 YYLPGSAPCRAVQMTAAAVGVELNLKLTNLM--AGEHMKPEFLKINPQHCIPTLVDNGFA 61 Query: 69 IVQSLAIMEYLEETRP-IPRLLPQDPQKRAIV--RMISDLIASGIQPLQNLSVLKQVGQE 125 + +S AI YL E +L P+DPQKRA+V R+ D+ + Q + + ++ Sbjct: 62 LWESRAICTYLAEKYGKDDKLYPKDPQKRAVVNQRLYFDM-GTLYQRFADYYYPQIFAKQ 120 Query: 126 NQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDLSPYPT 185 +K + + L L KY GD +++AD+ ++ V+ + +L+ YP Sbjct: 121 PANAENEKKMKDAVDFLNTFLDGH--KYVAGDSLTIADLTVLATVSTYDVAGFELAKYPH 178 Query: 186 ISHINKE 192 ++ + Sbjct: 179 VAAWYER 185 >4YH2-A nrPDB Length = 222 Score = 159 bits (401), Expect = 1e-39, Method: Composition-based stats. Identities = 58/205 (28%), Positives = 93/205 (45%), Gaps = 13/205 (6%) Query: 5 KPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKI 64 K LY S V++ LA + YE V ++++ Q + E+ NP VP L+ Sbjct: 3 KLTLYGLDPSPPVRAVKLTLAALNLTYEYVNVDIVARA--QLSPEYLEKNPQHTVPTLED 60 Query: 65 DGITIVQSLAIMEYLEETRPI-PRLLPQDPQKRAIVRMISDL-----IASGIQPLQNLSV 118 DG I S AI+ YL L P+DP KRA+V A+GI+ + + Sbjct: 61 DGHYIWDSHAIIAYLVSKYADSDALYPKDPLKRAVVDQRLHFESGVVFANGIRSISKSVL 120 Query: 119 LKQVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERF-K 177 + GQ + I ++ +E L+ Y G+++++AD LV VA+ E F Sbjct: 121 FQ--GQTKVPKERYDAIIEIYDFVETFLK--GQDYIAGNQLTIADFSLVSSVASLEAFVA 176 Query: 178 VDLSPYPTISHINKELLALEVFQVS 202 +D + YP I K+L L ++ + Sbjct: 177 LDTTKYPRIGAWIKKLEQLPYYEEA 201 >1PN9-A nrPDB Length = 209 Score = 157 bits (398), Expect = 2e-39, Method: Composition-based stats. Identities = 49/190 (25%), Positives = 86/190 (45%), Gaps = 8/190 (4%) Query: 9 YSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGIT 68 Y S+ V++ A G++ + +L+K G+ EF LNP +P L +G Sbjct: 4 YYLPGSAPCRAVQMTAAAVGVELNLKLTDLMK--GEHMKPEFLKLNPQHCIPTLVDNGFA 61 Query: 69 IVQSLAIMEYLEETRP-IPRLLPQDPQKRAIV--RMISDLIASGIQPLQNLSVLKQVGQE 125 + +S AI YL E +L P+DPQKRA+V R+ D+ + Q + + ++ Sbjct: 62 LWESRAIQIYLAEKYGKDDKLYPKDPQKRAVVNQRLYFDM-GTLYQRFADYHYPQIFAKQ 120 Query: 126 NQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDLSPYPT 185 +K + L L+ +Y G+++++AD+ L +A E D +PYP Sbjct: 121 PANPENEKKMKDAVGFLNTFLE--GQEYAAGNDLTIADLSLAATIATYEVAGFDFAPYPN 178 Query: 186 ISHINKELLA 195 ++ A Sbjct: 179 VAAWFARCKA 188 >3VWX-A nrPDB Length = 222 Score = 156 bits (395), Expect = 6e-39, Method: Composition-based stats. Identities = 59/206 (28%), Positives = 91/206 (44%), Gaps = 13/206 (6%) Query: 4 GKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALK 63 GK +LY S + L + +E +NL + +EE+ NP VP L+ Sbjct: 2 GKLVLYGIDPSPPVRACLLTLKALNLPFEYKVVNLFAK--EHLSEEYLKKNPQHTVPTLE 59 Query: 64 IDGITIVQSLAIMEYLEETRP-IPRLLPQDPQKRAIV--RMISD---LIASGIQPLQNLS 117 DG I S AIM YL L P+D KRA+V RM + L G++ + Sbjct: 60 EDGHLIWDSHAIMAYLVSKYGKDDSLYPKDLLKRAVVDQRMYFEAGVLFQGGLRNITAPL 119 Query: 118 VLKQVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERF- 176 + Q Q Q I + LE L++ KY GD +++AD +V V + F Sbjct: 120 FFRNQTQIPQHQI--DSIVESYGFLESFLKNN--KYMAGDHLTIADFSIVTSVTSLVAFA 175 Query: 177 KVDLSPYPTISHINKELLALEVFQVS 202 ++D S +P +S K L +L ++ + Sbjct: 176 EIDQSKFPKLSAWLKSLQSLPFYEEA 201 >5J5N-A nrPDB Length = 231 Score = 155 bits (391), Expect = 2e-38, Method: Composition-based stats. Identities = 55/194 (28%), Positives = 85/194 (43%), Gaps = 19/194 (9%) Query: 1 MQAGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNP-MKQV 59 M + + L ++ S RVR+ALA KG+ YE +L + +NP KQ+ Sbjct: 12 MASDQVTLLDFWPSPFGMRVRLALAEKGVKYEYSEEDLW-----NKSALLLQMNPVNKQI 66 Query: 60 PALKIDGITIVQSLAIMEYLEETRPIP-RLLPQDPQKRAIVRMISDLIASGIQPLQNLSV 118 P L +G + +SL I++Y++E LLP DP +RA R +D + I L + Sbjct: 67 PVLVHNGKPVCESLIIVQYIDEVWKDSAPLLPSDPYQRAQSRFWADFVDKKIYDLGR-KI 125 Query: 119 LKQVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKV 178 + G+E + A+K +E L Y G+ + D+ LVP F Sbjct: 126 WTKKGEEQEA--AKKDFIDSLKLMEGELGDK--PYFGGETIGYVDIALVP-------FYS 174 Query: 179 DLSPYPTISHINKE 192 Y TI + N E Sbjct: 175 WFYAYETIGNFNIE 188 >4J2F-A nrPDB Length = 223 Score = 155 bits (391), Expect = 2e-38, Method: Composition-based stats. Identities = 55/216 (25%), Positives = 90/216 (41%), Gaps = 24/216 (11%) Query: 3 AGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQ-VPA 61 A L+ + S S RV AL LKGI YE V +L + NP+ + +P Sbjct: 2 AEVLKLHGAWPSPFSCRVIWALKLKGIPYEYVEEDLF-----NKSPLLLQYNPVHKKIPV 56 Query: 62 LKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQ 121 L G I +S I+EYL+ET P LLP DP +RA+ R I + N + + Sbjct: 57 LVHGGKPICESTIILEYLDETWPENPLLPSDPHERAVARFWVKFIEDKGTAIWN--IFRT 114 Query: 122 VGQENQMQWAQKVITSGFNALEKILQSTAG----KYCVGDEVSMADVC---LVPQVANAE 174 G+E +K + + L+ I + G KY GD++ + D+ + + E Sbjct: 115 KGEE-----LEKAVKNCLEVLKTIEEHAMGVSDDKYFGGDKIGIVDIAFCGIAHWLGVIE 169 Query: 175 RFK----VDLSPYPTISHINKELLALEVFQVSHPRR 206 ++ +P + + + + + P R Sbjct: 170 EVAGVKVLESQKFPRLHAWTENFKEAPIIKENLPDR 205 >2VO4-A nrPDB Length = 219 Score = 154 bits (389), Expect = 3e-38, Method: Composition-based stats. Identities = 59/211 (27%), Positives = 91/211 (43%), Gaps = 17/211 (8%) Query: 4 GKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMK-QVPAL 62 + +L ++ S RVRIALA KGI YE +L + +NP+ ++P L Sbjct: 3 DEVVLLDFWPSPFGMRVRIALAEKGIKYEYKEEDLR-----NKSPLLLQMNPVHKKIPVL 57 Query: 63 KIDGITIVQSLAIMEYLEETRPIPR-LLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQ 121 +G I +SL ++Y+EE LLP DP +RA R +D + I L + Sbjct: 58 IHNGKPICESLIAVQYIEEVWNDRNPLLPSDPYQRAQTRFWADYVDKKIYDLGR-KIWTS 116 Query: 122 VGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFK---- 177 G+E + A+K LE+ L Y GD + D+ LVP + ++ Sbjct: 117 KGEEKEA--AKKEFIEALKLLEEQLGDKT--YFGGDNLGFVDIALVPFYTWFKAYETFGT 172 Query: 178 VDL-SPYPTISHINKELLALEVFQVSHPRRQ 207 +++ S P K L E S P +Q Sbjct: 173 LNIESECPKFIAWAKRCLQKESVAKSLPDQQ 203 >4CHS-A nrPDB Length = 219 Score = 153 bits (386), Expect = 6e-38, Method: Composition-based stats. Identities = 57/210 (27%), Positives = 90/210 (42%), Gaps = 17/210 (8%) Query: 4 GKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMK-QVPAL 62 + +L ++ S RVRIALA KGI+YE +L + +NP+ ++P L Sbjct: 3 DEVVLLDFWPSPFGMRVRIALAEKGIEYEYKEEDLR-----NKSPLLLQMNPVHKKIPVL 57 Query: 63 KIDGITIVQSLAIMEYLEETRPIPR-LLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQ 121 +G I +SL ++Y+EE LLP DP +RA R +D + I L + Sbjct: 58 IHNGKPISESLIAVQYIEEVWNDRNPLLPSDPYQRAQARFWADYVDIKIHDLGK-KIWTS 116 Query: 122 VGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFK---- 177 G+E + A+K LE+ L Y GD + D+ LVP + ++ Sbjct: 117 KGEEKEA--AKKEFIEALKLLEEQLGDKT--YFGGDNIGFVDIALVPFYTWFKVYETFGS 172 Query: 178 VDLSP-YPTISHINKELLALEVFQVSHPRR 206 +++ P K L E S P + Sbjct: 173 LNIENECPRFVAWAKRCLQKESVAKSLPDQ 202 >1B48-A nrPDB Length = 221 Score = 153 bits (386), Expect = 6e-38, Method: Composition-based stats. Identities = 49/222 (22%), Positives = 89/222 (40%), Gaps = 20/222 (9%) Query: 3 AGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPAL 62 A KP LY + +R LA G+++E + + + + QVP + Sbjct: 1 AAKPKLYYFNGRGRMESIRWLLAAAGVEFEEEFLETREQYEKMQKDGHLL---FGQVPLV 57 Query: 63 KIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQV 122 +IDG+ + Q+ AI+ YL L +D ++R + M +D G Q L + + Sbjct: 58 EIDGMMLTQTRAILSYLAAKY---NLYGKDLKERVRIDMYAD----GTQDLMMMIAVAPF 110 Query: 123 GQENQMQWAQKVI-----TSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFK 177 + + + +I T F EKIL+ + VG+++S AD+ L+ + E Sbjct: 111 KTPKEKEESYDLILSRAKTRYFPVFEKILKDHGEAFLVGNQLSWADIQLLEAILMVEELS 170 Query: 178 VD-LSPYPTISHINKELLALE----VFQVSHPRRQPDTPAEL 214 LS +P + + + Q R+ P + Sbjct: 171 APVLSDFPLLQAFKTRISNIPTIKKFLQPGSQRKPPPDGPYV 212 >3MAK-A nrPDB Length = 209 Score = 151 bits (382), Expect = 2e-37, Method: Composition-based stats. Identities = 49/187 (26%), Positives = 80/187 (42%), Gaps = 8/187 (4%) Query: 9 YSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGIT 68 Y SS V + G++ +NL G+ EF +NP +P L +G Sbjct: 5 YYLPGSSPCRSVIMTAKAVGVELNKKLLNL--QAGEHLKPEFLKINPQHTIPTLVDNGFA 62 Query: 69 IVQSLAIMEYLEETRP-IPRLLPQDPQKRAIV--RMISDLIASGIQPLQNLSVLKQVGQE 125 + +S AI YL E L P+ P+KRA++ R+ D+ + Q N + + Sbjct: 63 LWESRAIQVYLVEKYGKTDSLYPKCPKKRAVINQRLYFDM-GTLYQSFANYYYPQVFAKA 121 Query: 126 NQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDLSPYPT 185 A K I + F L L+ Y GD +++AD+ LV V+ E K ++S Y Sbjct: 122 PADPEAFKKIEAAFEFLNTFLE--GQDYAAGDSLTVADIALVATVSTFEVAKFEISKYAN 179 Query: 186 ISHINKE 192 ++ + Sbjct: 180 VNRWYEN 186 >3M3M-A nrPDB Length = 210 Score = 150 bits (380), Expect = 3e-37, Method: Composition-based stats. Identities = 53/207 (25%), Positives = 97/207 (46%), Gaps = 17/207 (8%) Query: 7 ILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKI-D 65 +Y +RS +++++ L L G+ YE ++++ GG TE F NP ++P L++ D Sbjct: 5 KVYGDYRSGNCYKIKLMLNLLGLPYEWQAVDIL--GGDTQTEAFLAKNPNGKIPVLELED 62 Query: 66 GITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQ- 124 G + +S AI+ +L + + LP +P+ R V +P ++ Q+ + Sbjct: 63 GTCLWESNAILNFLAD---GSQFLPSEPRLRTQVLQWQFFEQYSHEPYIAVARFIQLYEG 119 Query: 125 --ENQMQWAQKVITSGFNALEKILQS-TAGKYCVGDEVSMADVCLVPQVANAERFKVDLS 181 E + + K+ G+ AL+ + + + Y VG+ S+AD+ L A+ DLS Sbjct: 120 LPEERREEYLKLHKRGYKALDVMEKQLSRTPYLVGEHYSIADIALYAYTHVADEGGFDLS 179 Query: 182 PYPTISHINKELLALEVFQVSHPRRQP 208 YP I + + + HPR P Sbjct: 180 RYPGIQAWMQRVQS-------HPRHVP 199 >5ZWP-A nrPDB Length = 208 Score = 149 bits (376), Expect = 8e-37, Method: Composition-based stats. Identities = 47/193 (24%), Positives = 81/193 (41%), Gaps = 8/193 (4%) Query: 9 YSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGIT 68 Y S+ V + GI+ +NL G+ EF +NP +P L Sbjct: 4 YYLPGSAPCRSVLMTAKALGIELNKKLLNL--QAGEHLKPEFLKINPQHTIPTLVDGDFA 61 Query: 69 IVQSLAIMEYLEETRP-IPRLLPQDPQKRAIV--RMISDLIASGIQPLQNLSVLKQVGQE 125 + +S AIM YL E L P+ P+KRA++ R+ D+ + + + + + Sbjct: 62 LWESRAIMVYLVEKYGKTDSLFPKCPKKRAVINQRLYFDM-GTLYKSFADYYYPQIFAKA 120 Query: 126 NQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDLSPYPT 185 K I + F+ L L+ +Y GD +++AD+ L+ V+ E D+S YP Sbjct: 121 PADPELFKKIETAFDFLNTFLKGH--EYAAGDSLTVADLALLASVSTFEVASFDISKYPN 178 Query: 186 ISHINKELLALEV 198 ++ L + Sbjct: 179 VAKWYANLKTVAP 191 >1EV4-A nrPDB Length = 221 Score = 149 bits (375), Expect = 1e-36, Method: Composition-based stats. Identities = 48/212 (22%), Positives = 94/212 (44%), Gaps = 12/212 (5%) Query: 3 AGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPAL 62 +GKP+L+ + +R LA G++++ I +D + + QVP + Sbjct: 1 SGKPVLHYFNARGRMECIRFLLAAAGVEFDEKFIQSPEDLEKLKKDGNLM---FDQVPMV 57 Query: 63 KIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQV 122 +IDG+ + Q+ AI+ Y+ L +D ++RA++ M S+ I + + L + Sbjct: 58 EIDGMKLAQTRAILNYIATKYD---LYGKDMKERALIDMYSEGILDLTEMIMQLVICPPD 114 Query: 123 GQENQMQWAQKVIT-SGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVD-L 180 +E + A+ A EK+L+S Y VG++++ D+ L+ + E F L Sbjct: 115 QKEAKTALAKDRTKNRYLPAFEKVLKSHGQDYLVGNKLTRVDIHLLELLLYVEEFDASLL 174 Query: 181 SPYPTISHINKELLALE----VFQVSHPRRQP 208 + +P + + +L Q R+ P Sbjct: 175 TSFPLLKAFKSRISSLPNVKKFLQPGSQRKLP 206 >4QQ7-A nrPDB Length = 207 Score = 147 bits (370), Expect = 4e-36, Method: Composition-based stats. Identities = 52/198 (26%), Positives = 87/198 (43%), Gaps = 9/198 (4%) Query: 7 ILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDG 66 +LYS S R R+ L KG+D+EI ++L E+ +NP QVP L Sbjct: 7 VLYSGTTCPFSQRCRLVLFEKGMDFEIRDVDLF-----NKPEDISVMNPYGQVPILVERD 61 Query: 67 ITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVR-MISDLIASGIQPLQNLSVLKQVGQE 125 + + +S I EY++E P P+L+P DP +RA R + + + L K E Sbjct: 62 LILYESNIINEYIDERFPHPQLMPADPVQRARARLFLLNFEKELFVHVSTLENEKGKAAE 121 Query: 126 NQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDLSPYPT 185 + A+ I L I KY +G+E SM DV + P + + + ++LS Sbjct: 122 KNHEKARLAIRDRLTQLAPIFVKN--KYMLGEEFSMLDVAIAPLLWRLDHYGIELSKNAA 179 Query: 186 -ISHINKELLALEVFQVS 202 + + + + + + Sbjct: 180 PLMKYAERIFSRPAYIEA 197 >5ECL-B nrPDB Length = 223 Score = 146 bits (369), Expect = 6e-36, Method: Composition-based stats. Identities = 48/213 (22%), Positives = 82/213 (38%), Gaps = 19/213 (8%) Query: 3 AGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMK-QVPA 61 A PIL Y+ S R R+AL KG+++E + + NP+ ++P Sbjct: 8 ANLPILLDYWPSMFGMRARVALREKGVEFEYREEDFS-----NKSPLLLQSNPIHKKIPV 62 Query: 62 LKIDGITIVQSLAIMEYLEETRPIPR-LLPQDPQKRAIVRMISDLIASGIQPLQNLSVLK 120 L +G + +SL +++Y++E P P DP RA R +D + Q V Sbjct: 63 LVHNGKPVCESLNVVQYVDEAWPEKNPFFPSDPYGRAQARFWADFVDKKFTDAQ-FKVWG 121 Query: 121 QVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDL 180 + G+E + +K LE L Y GD D+ L+ + + ++ Sbjct: 122 KKGEEQEAG--KKEFIEAVKILESELGDK--PYFGGDSFGYVDISLITFSSWFQAYEK-F 176 Query: 181 SPY------PTISHINKELLALEVFQVSHPRRQ 207 + P + K + E S P + Sbjct: 177 GNFSIESESPKLIAWAKRCMEKESVSKSLPDSE 209 >5F06-A nrPDB Length = 216 Score = 146 bits (368), Expect = 8e-36, Method: Composition-based stats. Identities = 48/207 (23%), Positives = 91/207 (43%), Gaps = 13/207 (6%) Query: 6 PILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKID 65 LY S+C+ RV L K +D+E+VP++L G+ F NP Q+PAL+ D Sbjct: 2 LKLYGAPMSTCTSRVLTCLHEKNLDFELVPVDLF--AGEHKQPPFLAKNPFGQIPALEED 59 Query: 66 GITIVQSLAIMEYLEETRPI---PRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQ- 121 +T+ +S AI Y+ E + ++ ++ A V++ +++ + P V + Sbjct: 60 DLTLFESRAITSYIAEKFKGTGYDLIRHENLKEAASVKVWTEVESHRYNPAIAPIVFQFM 119 Query: 122 VGQENQMQWAQKVITSGFNALEKIL-----QSTAGKYCVGDEVSMADVCLVPQVANAERF 176 V Q +I L K+L + ++ KY GD S+AD+ +P + Sbjct: 120 VAPLRGNSPDQTIIDDNVEKLGKVLDIYEAKLSSTKYLAGDFYSLADLHHLPYTYYLMKT 179 Query: 177 KVD--LSPYPTISHINKELLALEVFQV 201 ++ P + +++ + F+ Sbjct: 180 PAASVVNERPHVKAWWEDISSRPAFKK 206 >5F0G-A nrPDB Length = 215 Score = 145 bits (366), Expect = 1e-35, Method: Composition-based stats. Identities = 47/187 (25%), Positives = 80/187 (42%), Gaps = 8/187 (4%) Query: 9 YSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGIT 68 Y V + G++ +N ++ G+Q EF LNP +P L +G + Sbjct: 4 YYMPGGGGCRTVIMVAKALGLELNKKLLNTME--GEQLKPEFVKLNPQHTIPTLVDNGFS 61 Query: 69 IVQSLAIMEYLEETRP-IPRLLPQDPQKRAIV--RMISDLIASGIQPLQNLSVLKQVGQE 125 I +S AI YL E LLP DP+KRA++ R+ D+ + + + Sbjct: 62 IWESRAIAVYLVEKYGKDDYLLPNDPKKRAVINQRLYFDM-GTLYESFAKYYYPLFRTGK 120 Query: 126 NQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDLSPYPT 185 K I + F L+ L+ +Y GD++++AD+ ++ V+ E + D S Y Sbjct: 121 PGSDEDLKRIETAFGFLDTFLE--GQEYVAGDQLTVADIAILSTVSTFEVSEFDFSKYSN 178 Query: 186 ISHINKE 192 +S Sbjct: 179 VSRWYDN 185 >5G5A-A nrPDB Length = 221 Score = 145 bits (366), Expect = 1e-35, Method: Composition-based stats. Identities = 49/215 (22%), Positives = 86/215 (40%), Gaps = 23/215 (10%) Query: 3 AGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMK-QVPA 61 A + IL ++ S R RIAL K + ++ +L + +NP+ ++P Sbjct: 2 ADEVILLDFWPSMFGMRTRIALEEKNVKFDYREQDLW-----NKSPILLEMNPVHKKIPV 56 Query: 62 LKIDGITIVQSLAIMEYLEETRPIP-RLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLK 120 L +G + +SL +EY++E P LLP DP +RA + D I + L + Sbjct: 57 LIHNGNPVCESLIQIEYIDEVWPSKTPLLPSDPYQRAQAKFWGDFIDKKVYASARL-IWG 115 Query: 121 QVGQENQMQWAQKVITSGFNALEKILQSTAGK--YCVGDEVSMADVCLVPQVANAERFKV 178 G+E++ F + K L+S G Y G+ D+ L+ + E ++ Sbjct: 116 AKGEEHEAG------KKEFIEILKTLESELGDKTYFGGETFGYVDIALIGFYSWFEAYEK 169 Query: 179 DLSPY------PTISHINKELLALEVFQVSHPRRQ 207 + P + K + E S P + Sbjct: 170 -FGSFSIEAECPKLIAWGKRCVERESVAKSLPDSE 203 >3UAR-A nrPDB Length = 227 Score = 144 bits (364), Expect = 2e-35, Method: Composition-based stats. Identities = 49/196 (25%), Positives = 84/196 (42%), Gaps = 5/196 (2%) Query: 9 YSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALK-IDGI 67 YF +CS I L G+D+E+ ++L +F +NP VPAL+ DG Sbjct: 5 LYYFPGACSLAPHIVLREAGLDFELENVDLGTKK-TGSGADFLQVNPKGYVPALQLDDGQ 63 Query: 68 TIVQSLAIMEYLEETRPIPRLLPQDP-QKRAIVRMISDLIASGIQPLQNLSVLKQVGQEN 126 + + I++YL + +P L+P +R + I++ I E Sbjct: 64 VLTEDQVILQYLADLKPESGLMPPSGTFERYRLLEWLAFISTEIHKTFGP-FWNPESPEA 122 Query: 127 QMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDLSPYPTI 186 Q A +++ + +E L++ G + +GD S+AD L + E K+DLS +P I Sbjct: 123 SKQIALGLLSRRLDYVEDRLEA-GGPWLMGDRYSVADAYLSTVLGWCEYLKIDLSKWPRI 181 Query: 187 SHINKELLALEVFQVS 202 + A Q + Sbjct: 182 LAYLERNQARPAVQAA 197 >1GUL-A nrPDB Length = 222 Score = 144 bits (363), Expect = 3e-35, Method: Composition-based stats. Identities = 49/220 (22%), Positives = 96/220 (43%), Gaps = 12/220 (5%) Query: 3 AGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPAL 62 A +P L+ VR LA G++++ + + + +QVP + Sbjct: 2 AARPKLHYPNGRGRMESVRWVLAAAGVEFDEEFLETKEQLYKLQDGNHLL---FQQVPMV 58 Query: 63 KIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQV 122 +IDG+ +VQ+ +I+ Y+ + L ++ ++R ++ M + ++ L LK Sbjct: 59 EIDGMKLVQTRSILHYIADKH---NLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPD 115 Query: 123 GQENQM-QWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAER-FKVDL 180 Q+ ++ AQK I F EKIL+ + VG+++S+ADV L+ + E L Sbjct: 116 DQQKEVVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNIL 175 Query: 181 SPYPTISHINKELLALE----VFQVSHPRRQPDTPAELRT 216 S +P + +L + + ++ P +RT Sbjct: 176 SAFPFLQEYTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRT 215 >3QAG-A nrPDB Length = 239 Score = 143 bits (360), Expect = 7e-35, Method: Composition-based stats. Identities = 49/193 (25%), Positives = 84/193 (43%), Gaps = 10/193 (5%) Query: 4 GKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALK 63 G +YS S R R+ L K I +E+V INL E + T +P +P L+ Sbjct: 22 GLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLR-----NKPEWYYTKHPFGHIPVLE 76 Query: 64 ID-GITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQV 122 I +S+ EYL++ P +L P DP +RA +M+ +L + + V + Sbjct: 77 TSQSQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFSKVPHLTKECLVALRS 136 Query: 123 GQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVD--L 180 G+E+ + + F+ LE+IL+ + G +SM D L P + + + + Sbjct: 137 GRESTN--LKAALRQEFSNLEEILEYQNTTFFGGTSISMIDYLLWPWFERLDVYGILDCV 194 Query: 181 SPYPTISHINKEL 193 S P + + Sbjct: 195 SHTPALRLWISAM 207 >3GH6-A nrPDB Length = 210 Score = 143 bits (360), Expect = 7e-35, Method: Composition-based stats. Identities = 44/194 (22%), Positives = 80/194 (41%), Gaps = 7/194 (3%) Query: 8 LYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGI 67 LY S+ V + G++++ I + +QFT E+ +NP +P L G Sbjct: 3 LYYRPGSAPCRSVLMTAKALGVEFDKKTI-INTRAREQFTPEYLKINPQHTIPTLHDHGF 61 Query: 68 TIVQSLAIMEYLEETRP-IPRLLPQDPQKRAIV--RMISDLIASGIQPLQNLSVLKQVGQ 124 + +S AIM YL E +L P+D QK+A++ R+ D+ + + + + Sbjct: 62 ALWESRAIMVYLVEKYGKDDKLFPKDVQKQALINQRLYFDM-GTLYKSFSEYYYPQIFLK 120 Query: 125 ENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDLSPYP 184 + + K I F L L+ Y G + S+AD+ + V+ + D Y Sbjct: 121 KPANEENYKKIEVAFEFLNTFLE--GQTYSAGGDYSLADIAFLATVSTFDVAGFDFKRYA 178 Query: 185 TISHINKELLALEV 198 ++ + L Sbjct: 179 NVARWYENAKKLTP 192 >3M8N-A nrPDB Length = 225 Score = 142 bits (357), Expect = 1e-34, Method: Composition-based stats. Identities = 52/201 (25%), Positives = 87/201 (43%), Gaps = 15/201 (7%) Query: 7 ILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKID- 65 LYS RS S++VR+ALAL Y V +++++ G+ T +F NP QVP L+ Sbjct: 5 KLYSMQRSGNSYKVRLALALLDAPYRAVEVDILR--GESRTPDFLAKNPSGQVPLLETAP 62 Query: 66 GITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQP----LQNLSVLKQ 121 G + +S AI+ YL L P RA ++P L + Sbjct: 63 GRYLAESNAILWYLA---VGTSLAPDTRMDRAEALQWMFFEQHALEPNIGSAYFWLCLVK 119 Query: 122 VGQENQMQWAQKVITSGFNAL---EKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKV 178 G++ Q + + G+ AL E L+ Y ++++AD+ L A++ Sbjct: 120 GGRDLQTHALEDWLERGYAALQVMENHLK--TNDYFAAGQLTIADIALYGYTHVADQCDF 177 Query: 179 DLSPYPTISHINKELLALEVF 199 DLS +P ++ + + F Sbjct: 178 DLSTFPAVNAWLRRVEQTPGF 198 >2GDR-A nrPDB Length = 202 Score = 142 bits (357), Expect = 2e-34, Method: Composition-based stats. Identities = 42/196 (21%), Positives = 91/196 (46%), Gaps = 6/196 (3%) Query: 9 YSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALK-IDGI 67 Y +CS IAL G+++E+V ++L +++ +NP VP L+ DG Sbjct: 3 LYYSPGACSLSPHIALREAGLNFELVQVDLASKK-TASGQDYLEVNPAGYVPCLQLDDGR 61 Query: 68 TIVQSLAIMEYLEETRPIPRLLPQDP-QKRAIVRMISDLIASGIQPLQNLSVLKQVGQEN 126 T+ + AI++Y+ + P +L P + +R ++ + I+S + + + + Sbjct: 62 TLTEGPAIVQYVADQVPGKQLAPANGSFERYHLQQWLNFISSELHKSFSP-LFNPASSDE 120 Query: 127 QMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDLSPYPTI 186 ++ + + + + L+ Y +GD++S+AD+ L + + +DLSP+P++ Sbjct: 121 WKNAVRQSLNTRLGQVARQLEH--APYLLGDQLSVADIYLFVVLGWSAYVNIDLSPWPSL 178 Query: 187 SHINKELLALEVFQVS 202 + E Q + Sbjct: 179 QAFQGRVGGREAVQSA 194 >5ELG-A nrPDB Length = 221 Score = 140 bits (354), Expect = 3e-34, Method: Composition-based stats. Identities = 49/201 (24%), Positives = 82/201 (40%), Gaps = 24/201 (11%) Query: 13 RSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQS 72 S R + L K + Y+I INL + F ++P +VP LKID + S Sbjct: 19 DCPFSQRALLTLEEKSLTYKIHLINLSDK-----PQWFLDISPQGKVPVLKIDDKWVTDS 73 Query: 73 LAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQ 132 I+ LEE P P L + P + A V G + ++ ++ Sbjct: 74 DVIVGILEEKYPDPPL--KTPAEFASV---------GSNIFGTFGTF--LKSKDSNDGSE 120 Query: 133 KVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAE----RFKVDLSP--YPTI 186 + ALE L+S G + G+ VS D+ L P++ + + FK P +P + Sbjct: 121 HALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHV 180 Query: 187 SHINKELLALEVFQVSHPRRQ 207 + K L +L+ F+ + + Sbjct: 181 HNYMKTLFSLDSFEKTKTEEK 201 >3LFL-A nrPDB Length = 240 Score = 140 bits (352), Expect = 6e-34, Method: Composition-based stats. Identities = 52/201 (25%), Positives = 85/201 (42%), Gaps = 12/201 (5%) Query: 4 GKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALK 63 G +YS + R R+ L KGI +E++ INL + E F NP VP L+ Sbjct: 22 GSIRIYSMRFCPFAERTRLVLKAKGIRHEVININL-----KNKPEWFFKKNPFGLVPVLE 76 Query: 64 ID-GITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQV 122 G I +S EYL+E P +LLP DP ++A +MI +L + P S ++ Sbjct: 77 NSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKV--PSLVGSFIRSQ 134 Query: 123 GQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVD--L 180 +E+ ++ F LE +L + + G+ +SM D + P E K++ + Sbjct: 135 NKEDYAGLKEE-FRKEFTKLE-VLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECV 192 Query: 181 SPYPTISHINKELLALEVFQV 201 P + + Sbjct: 193 DHTPKLKLWMAAMKEDPTVSA 213 >5F07-A nrPDB Length = 213 Score = 139 bits (351), Expect = 7e-34, Method: Composition-based stats. Identities = 42/209 (20%), Positives = 87/209 (41%), Gaps = 17/209 (8%) Query: 6 PILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKID 65 +Y + C RV L KG+++++V ++L D G+Q EF P QVP ++ Sbjct: 2 VKVYGPAVAVCPQRVMACLLEKGVEFDLVHVDL--DSGEQKLPEFLLKQPFGQVPVVEDG 59 Query: 66 GITIVQSLAIMEYLEETRPI--PRLLPQDPQKRAIVRMISDLIASGIQPL-----QNLSV 118 + +S AI+ Y P LL +++A+V ++ A L + + Sbjct: 60 DFKLFESRAIIRYYAAKYEDRGPNLLGNTLEEKALVDQWLEIEAHNFNDLVFNIVFQVVI 119 Query: 119 LKQVGQENQMQWA---QKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANA-- 173 L ++GQ+ + ++ + + EK L + KY GD ++AD+ +P Sbjct: 120 LPRIGQQGDSELVRTYEEKLEKVLDVYEKRLSKS--KYLAGDSFTLADLSHLPATRYLVN 177 Query: 174 -ERFKVDLSPYPTISHINKELLALEVFQV 201 + ++ +++ + ++ Sbjct: 178 EAGLGHLVKDRKKLNAWWEDISSRPAWKK 206 >6EP7-A nrPDB Length = 220 Score = 139 bits (350), Expect = 1e-33, Method: Composition-based stats. Identities = 49/211 (23%), Positives = 88/211 (41%), Gaps = 21/211 (9%) Query: 4 GKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMK-QVPAL 62 + IL Y+ S R RIAL K + YE +L + +NP+ ++P L Sbjct: 3 EEIILLDYWASMYGMRTRIALEEKKVKYEYREEDLS-----NKSPLLLQMNPIHKKIPVL 57 Query: 63 KIDGITIVQSLAIMEYLEETRPIPR-LLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQ 121 +G I +S+ ++Y++E P +LP DP +RA R +D I + ++ + Sbjct: 58 IHEGKPICESIIQVQYIDELWPDTNPILPSDPYQRAQARFWADYIDKKTY-VPCKALWSE 116 Query: 122 VGQENQMQWAQKVITSGFNALEKILQSTAGK--YCVGDEVSMADVCLVPQVANAERFK-- 177 G++ Q+ F + K L S G Y G+E + D+ + + ++ Sbjct: 117 SGEK------QEAAKIEFIEVLKTLDSELGDKYYFGGNEFGLVDIAFIGFYSWFRTYEEV 170 Query: 178 VDLS---PYPTISHINKELLALEVFQVSHPR 205 +LS +P + + L E + P Sbjct: 171 ANLSIVLEFPKLMAWAQRCLKRESVAKALPD 201 >5LOL-A nrPDB Length = 215 Score = 136 bits (342), Expect = 7e-33, Method: Composition-based stats. Identities = 47/213 (22%), Positives = 93/213 (43%), Gaps = 26/213 (12%) Query: 1 MQAGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVP 60 + G P + S RV + L K + Y+ IN+ + F ++P +VP Sbjct: 11 VAVGAPDVLG--DCPFSQRVLLTLEEKKLPYKTHLINVSD-----KPQWFLDISPEGKVP 63 Query: 61 ALKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLK 120 +K+DG + S I+ LEE P P L + P + A V S + + + L Sbjct: 64 VVKLDGKWVADSDVIVGLLEEKYPEPSL--KTPPEFASV--GSKIFGAFVTFL------- 112 Query: 121 QVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAE----RF 176 ++ ++K + ALE L++ +G + G++++ D+ L P++ + E + Sbjct: 113 --KSKDANDGSEKALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHY 170 Query: 177 KVDLSP--YPTISHINKELLALEVFQVSHPRRQ 207 K P ++ + K L + E F+ + +++ Sbjct: 171 KNWSVPESLTSVRNYAKALFSRESFENTKAKKE 203 >4MDC-A nrPDB Length = 252 Score = 135 bits (341), Expect = 1e-32, Method: Composition-based stats. Identities = 54/219 (24%), Positives = 90/219 (41%), Gaps = 23/219 (10%) Query: 6 PILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKID 65 P LY + S S VR+ L+ G E L ++ + +F TLNP +P D Sbjct: 24 PTLYHHPMSPASRFVRLILSEYGYQTE-----LSEEQPWENRRDFLTLNPAGTLPVYVDD 78 Query: 66 GI-TIVQSLAIMEYLEETRP----IPRLLPQDPQKRAIVRMISDLI-----ASGIQPLQN 115 + + + I EYL+ET RLL +DP +RA +R +++ A +PL Sbjct: 79 SMRALCGATIISEYLDETSGIMKRDRRLLAEDPFQRAEIRRLTEWFLQKMEADVTRPLVR 138 Query: 116 LSVLKQVGQENQMQWAQ--KVITSGFNALE---KILQSTAG--KYCVGDEVSMADVCLVP 168 + K +Q A K++ + + + K L AG + GD +S D+ Sbjct: 139 ERIFKLQMTPDQGGGAPDSKILRTSRSNIRQHMKYLSWLAGSRPWLAGDRISYGDLAAAA 198 Query: 169 QVANAERFK-VDLSPYPTISHINKELLALEVFQVSHPRR 206 ++ + +D S PT + L + F+ R Sbjct: 199 AISVLDYLGEIDWSDAPTAKEWYQRLKSRPSFRPLLAER 237 >5IQY-A nrPDB Length = 216 Score = 135 bits (340), Expect = 1e-32, Method: Composition-based stats. Identities = 55/202 (27%), Positives = 86/202 (42%), Gaps = 26/202 (12%) Query: 13 RSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKI-DGITIVQ 71 S RV + L K I YE+ ++L E F ++P +VP DG I Sbjct: 22 DCPFSQRVLLTLEEKKITYEMKLVDLS-----NKPEWFLKISPEGKVPVFNSGDGKWIAD 76 Query: 72 SLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQWA 131 S I + +EE P P L+ P + A V S I P S +K + ++ + Sbjct: 77 SDVITQVIEEKFPTPSLV--TPPEYASV-------GSKIFP----SFVKFLKSKDASDGS 123 Query: 132 QKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVAN----AERFKVDLSP--YPT 185 +K + AL++ L++ G Y G+ VS AD+ L P++ + E FK P + Sbjct: 124 EKALLDELQALDEHLKAH-GPYISGENVSAADLSLGPKLFHLQVALEHFKGWKIPENLTS 182 Query: 186 ISHINKELLALEVFQVSHPRRQ 207 + K L + E F + P Q Sbjct: 183 VHAYTKALFSRESFVKTKPANQ 204 >2IL3-A nrPDB Length = 221 Score = 135 bits (339), Expect = 2e-32, Method: Composition-based stats. Identities = 44/201 (21%), Positives = 78/201 (38%), Gaps = 9/201 (4%) Query: 6 PILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKID 65 +LY+ S V + G++ E INL+ G EF LNP +P L + Sbjct: 4 LVLYTLHLSPPCRAVELTAKALGLELEQKTINLLT--GDHLKPEFVKLNPQHTIPVLDDN 61 Query: 66 GITIVQSLAIMEYLEETRP-IPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLK--QV 122 G I +S AIM YL L P+DP K+A V + + + Sbjct: 62 GTIITESHAIMIYLVTKYGKDDSLYPKDPVKQARVNSALHFESGVLFARMRFIFERILFF 121 Query: 123 GQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANA-ERFKVDLS 181 G+ + + + + + LE L + G +++AD + +++ ++ S Sbjct: 122 GKSDIPEDRVEYVQKSYELLEDTLVD---DFVAGPTMTIADFSCISTISSIMGVVPLEQS 178 Query: 182 PYPTISHINKELLALEVFQVS 202 +P I L L ++ + Sbjct: 179 KHPRIYAWIDRLKQLPYYEEA 199 >3GX0-A nrPDB Length = 215 Score = 134 bits (337), Expect = 3e-32, Method: Composition-based stats. Identities = 40/214 (18%), Positives = 90/214 (42%), Gaps = 17/214 (7%) Query: 9 YSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDG-- 66 + + ++ + L +DY ++ ++L K G QF EF ++P ++PA+ Sbjct: 4 LYFAPTPNGHKITLFLEEAELDYRLIKVDLGK--GGQFRPEFLRISPNNKIPAIVDHSPA 61 Query: 67 -----ITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPL----QNLS 117 +++ +S AI+ YL E + L + ++RA G+ P+ + + Sbjct: 62 DGGEPLSLFESGAILLYLAEKTGL--FLSHETRERAATLQWLFWQVGGLGPMLGQNHHFN 119 Query: 118 VLKQVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFK 177 ++ Q ++ L K L+++ + G+ S+AD+ P V R + Sbjct: 120 HAAPQTIPYAIERYQVETQRLYHVLNKRLENS--PWLGGENYSIADIACWPWVNAWTRQR 177 Query: 178 VDLSPYPTISHINKELLALEVFQVSHPRRQPDTP 211 +DL+ YP + + ++ + + + + Q Sbjct: 178 IDLAMYPAVKNWHERIRSRPATGQALLKAQLGDE 211 >5D9W-A nrPDB Length = 230 Score = 130 bits (326), Expect = 6e-31, Method: Composition-based stats. Identities = 48/202 (23%), Positives = 84/202 (41%), Gaps = 26/202 (12%) Query: 13 RSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALK-IDGITIVQ 71 S S RV + L K + YE+ I++ Q + F ++P +VP DG I Sbjct: 36 DSPFSQRVLLTLEEKKVPYEMKLIDV-----QNKPDWFLKISPEGKVPVFNGGDGKWIPD 90 Query: 72 SLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQWA 131 S I + +EE P P L+ P + A V S + + L ++ + Sbjct: 91 SDVITQVIEEKYPTPSLV--TPPEYASV--GSKIFSCFTTFL---------KSKDPNDGS 137 Query: 132 QKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVAN----AERFKVDLSP--YPT 185 +K + + ALE+ L++ G + G +S AD+ L P++ + E FK P Sbjct: 138 EKALLTELQALEEHLKAH-GPFINGQNISAADLSLAPKLYHLQVALEHFKGWKIPEDLTN 196 Query: 186 ISHINKELLALEVFQVSHPRRQ 207 + + L + E F + ++ Sbjct: 197 VHAYTEALFSRESFIKTKAAKE 218 >5EY6-A nrPDB Length = 217 Score = 130 bits (326), Expect = 6e-31, Method: Composition-based stats. Identities = 43/211 (20%), Positives = 83/211 (39%), Gaps = 14/211 (6%) Query: 3 AGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPAL 62 A +Y S+ RV + L K + ++I+P+++ K G+ ++ + P QVPA Sbjct: 1 ATPVKVYGPPLSTAVSRVLVTLLEKDVPFQIIPVDMSK--GEHKKPDYLKIQPFGQVPAF 58 Query: 63 KIDGITIVQSLAIMEYLEETR---PIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVL 119 + + I++ +S +I Y+ E L +P +RA + + P V Sbjct: 59 QDESISLFESRSICRYVCEKYADRGDKGLYGTNPLERASIDQWVEAEGQSFGPSSGALVF 118 Query: 120 K-QVGQENQMQWAQKVITSGFNALEKIL-----QSTAGKYCVGDEVSMADVCLVP---QV 170 + + Q VI L K+L + ++ GDE + AD+ +P + Sbjct: 119 QLAFAPRMNIPQDQGVIKQNEEKLGKVLDIYEQRLGESRFLAGDEFTFADLSHLPNGDYL 178 Query: 171 ANAERFKVDLSPYPTISHINKELLALEVFQV 201 NA + + E+ E ++ Sbjct: 179 VNATDKGHLFTSRENVGRWWNEISDRESWKK 209 >1AXD-A nrPDB Length = 209 Score = 128 bits (323), Expect = 1e-30, Method: Composition-based stats. Identities = 53/203 (26%), Positives = 81/203 (39%), Gaps = 10/203 (4%) Query: 7 ILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDG 66 LY S R AL G DYEIVPIN + + E NP QVPAL+ Sbjct: 4 KLYGAVMSWNLTRCATALEEAGSDYEIVPINFAT--AEHKSPEHLVRNPFGQVPALQDGD 61 Query: 67 ITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQEN 126 + + +S AI +Y L + ++ A+V + ++ A+ N + + + Sbjct: 62 LYLFESRAICKYAARKNKPELLREGNLEEAAMVDVWIEVEANQYTAALNPILFQVLISPM 121 Query: 127 QMQWA-QKVITSGFNALEKILQ-----STAGKYCVGDEVSMADVCLVPQV--ANAERFKV 178 QKV+ L+K+L+ T KY GD +S+AD+ V A + Sbjct: 122 LGGTTDQKVVDENLEKLKKVLEVYEARLTKCKYLAGDFLSLADLNHVSVTLCLFATPYAS 181 Query: 179 DLSPYPTISHINKELLALEVFQV 201 L YP + L+ Q Sbjct: 182 VLDAYPHVKAWWSGLMERPSVQK 204 >1AW9-A nrPDB Length = 216 Score = 128 bits (323), Expect = 1e-30, Method: Composition-based stats. Identities = 48/218 (22%), Positives = 80/218 (36%), Gaps = 17/218 (7%) Query: 6 PILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKID 65 LY S RV L KG+D+EIVP++L G +F LNP Q+PAL Sbjct: 3 LKLYGMPLSPNVVRVATVLNEKGLDFEIVPVDLTT--GAHKQPDFLALNPFGQIPALVDG 60 Query: 66 GITIVQSLAIMEYLEETRP--IPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQV- 122 + +S AI Y+ LLP A + + ++ + P + V + + Sbjct: 61 DEVLFESRAINRYIASKYASEGTDLLPATASA-AKLEVWLEVESHHFYPNASPLVFQLLV 119 Query: 123 -----GQENQMQWAQKV--ITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAER 175 G + + + + E L KY GDE ++AD + + Sbjct: 120 RPLLGGAPDAAVVDKHAEQLAKVLDVYEAHL--ARNKYLAGDEFTLADANHASYLLYLSK 177 Query: 176 FKVD--LSPYPTISHINKELLALEVFQVSHPRRQPDTP 211 ++ P + + ++A FQ + P Sbjct: 178 TPKAGLVAARPHVKAWWEAIVARPAFQKTVAAIPLPPP 215 >1F2E-A nrPDB Length = 201 Score = 127 bits (320), Expect = 3e-30, Method: Composition-based stats. Identities = 46/192 (23%), Positives = 85/192 (44%), Gaps = 6/192 (3%) Query: 13 RSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKID-GITIVQ 71 +CS IAL G D+E V ++L + E+F T+NP +VPAL +D G T+ + Sbjct: 7 PGACSLAPHIALRETGADFEAVKVDLAVRKTEA-GEDFLTVNPSGKVPALTLDSGETLTE 65 Query: 72 SLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQWA 131 + AI+ Y+ + P L P + R++S L G + + L ++ + A Sbjct: 66 NPAILLYIADQNPASGLAPAEGSLD-RYRLLSRLSFLGSEFHKAFVPLFAPATSDEAKAA 124 Query: 132 Q-KVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDLSPYPTISHIN 190 + + + AL+K L + G+ S+AD+ L + +D++ YP + Sbjct: 125 AAESVKNHLAALDKELAGR--DHYAGNAFSVADIYLYVMLGWPAYVGIDMAAYPALGAYA 182 Query: 191 KELLALEVFQVS 202 ++ + Sbjct: 183 GKIAQRPAVGAA 194 >2PMT-A nrPDB Length = 203 Score = 127 bits (320), Expect = 3e-30, Method: Composition-based stats. Identities = 41/197 (20%), Positives = 81/197 (41%), Gaps = 8/197 (4%) Query: 9 YSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALK-IDGI 67 Y SCS I L G+D+ I I+L + ++F +NP QVP L+ +G Sbjct: 3 LYYTPGSCSLSPHIVLRETGLDFSIERIDLRTKKTES-GKDFLAINPKGQVPVLQLDNGD 61 Query: 68 TIVQSLAIMEYLEETRPIPRLL--PQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQE 125 + + +AI++YL + +P L+ P+ ++ + + +AS + + + E Sbjct: 62 ILTEGVAIVQYLADLKPDRNLIAPPKALERYHQIE-WLNFLASEVHKGYSP-LFSSDTPE 119 Query: 126 NQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDLSPYPT 185 + + + + S F + +L + K GD ++AD L A +DL+ Sbjct: 120 SYLPVVKNKLKSKFVYINDVL--SKQKCVCGDHFTVADAYLFTLSQWAPHVALDLTDLSH 177 Query: 186 ISHINKELLALEVFQVS 202 + + + Sbjct: 178 LQDYLARIAQRPNVHSA 194 >3TOT-A nrPDB Length = 226 Score = 126 bits (317), Expect = 7e-30, Method: Composition-based stats. Identities = 46/210 (21%), Positives = 89/210 (42%), Gaps = 16/210 (7%) Query: 7 ILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALK-ID 65 L S + +VR+ LA K IDY+ V ++ Q NP+ +VP L D Sbjct: 4 KLIGSHASPYTRKVRVVLAEKKIDYQFVLEDVWNADTQ-----IHQFNPLGKVPCLVMDD 58 Query: 66 GITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQE 125 G + S I EY + P+ RL+P ++R VR L + L V + Sbjct: 59 GGALFDSRVIAEYADTLSPVARLIPPSGRERVEVRCWEALADGLLDAAVALRVEQTQRTP 118 Query: 126 NQMQWAQKVITSGFNALEKILQSTA-----GKYCVGDEVSMADVCLVPQVANAE--RFKV 178 Q ++ IT + +++ L++ + +C G+ +++AD+ + +A + + +V Sbjct: 119 E--QRSESWITRQHHKIDEALKAMSRGLADRTWCNGNHLTLADIAVGCALAYLDFRQPQV 176 Query: 179 DL-SPYPTISHINKELLALEVFQVSHPRRQ 207 D + ++ + F + P+ + Sbjct: 177 DWREQHANLAAFYTRIEKRPSFLETQPQAE 206 >3WD6-A nrPDB Length = 256 Score = 125 bits (315), Expect = 9e-30, Method: Composition-based stats. Identities = 58/217 (26%), Positives = 100/217 (46%), Gaps = 26/217 (11%) Query: 4 GKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALK 63 GK +Y+ + R +AL K IDYE+V I+LI E T + +VPA++ Sbjct: 28 GKLRVYNMRYCPYAQRTILALNAKQIDYEVVNIDLIDK-----PEWLTTKSAFAKVPAIE 82 Query: 64 I-DGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQV 122 I + +TI +SL +EYL+E P LLPQDP K+A+ ++I + A P+Q+L + Sbjct: 83 IAEDVTIYESLVTVEYLDEVYPKRPLLPQDPLKKALDKIIVEASA----PIQSLFIKILK 138 Query: 123 GQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANA------ERF 176 + + + +++ L++ + G E AD + P ER Sbjct: 139 FSDTVNEEHVAAYHKALDFIQEQLKNRGTVFLDGSEPGYADYMIWPWFERLRAFAHDERV 198 Query: 177 KVDLSPYPTI----------SHINKELLALEVFQVSH 203 +++ S Y + S +++ L+ LE+ H Sbjct: 199 RLEPSKYSLLLEYIDNMLKDSAVSQYLIPLEILAKFH 235 >6F05-A nrPDB Length = 215 Score = 124 bits (312), Expect = 2e-29, Method: Composition-based stats. Identities = 47/214 (21%), Positives = 86/214 (40%), Gaps = 26/214 (12%) Query: 6 PILYS-YFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKI 64 +Y +F S R + L KG+ +E +P++L+K G+ + L P VPA+ Sbjct: 3 LKVYGPHFASP--KRALVTLIEKGVAFETIPVDLMK--GEHKQPAYLALQPFGTVPAVVD 58 Query: 65 DGITIVQSLAIMEYLEETR--PIPRLLPQDPQKRAIVRMISDLIASGIQP--------LQ 114 I +S A+M Y+ E P LL + + R V D+ A+ P + Sbjct: 59 GDYKIFESRAVMRYVAEKYRSQGPDLLGKTVEDRGQVEQWLDVEATTYHPPLLNLTLHIM 118 Query: 115 NLSVLKQVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANA- 173 SV+ E ++ +++ + + E L + KY GD VS+AD+ +P Sbjct: 119 FASVMGFPSDEKLIKESEEKLAGVLDVYEAHLSKS--KYLAGDFVSLADLAHLPFTDYLV 176 Query: 174 -----ERFKVDLSPYPTISHINKELLALEVFQVS 202 D +S ++ + ++ + Sbjct: 177 GPIGKAYMIKDRK---HVSAWWDDISSRPAWKET 207 >3LSZ-A nrPDB Length = 225 Score = 123 bits (310), Expect = 4e-29, Method: Composition-based stats. Identities = 43/211 (20%), Positives = 87/211 (41%), Gaps = 20/211 (9%) Query: 6 PILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEE---------FQTLNPM 56 +Y +RS S R LA + +E VP+ E + +NP+ Sbjct: 3 LKIYGVYRSRAS-RPLWLLAELDLPFEHVPVIQANRVAHPHGPEAPLNTASAAYLAVNPL 61 Query: 57 KQVPALKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQP-LQN 115 Q+P L+ +G+ + +SLAI ++ T+ +L P+ + A++ S A+ ++P Sbjct: 62 GQIPCLEEEGLILTESLAITLHIARTQGG-QLGPRSEPEDALMVSWSLFAATAVEPPALE 120 Query: 116 LSVLKQVGQENQMQW------AQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQ 169 + ++++ G + A + + LE+ A Y VG ++AD+ L Sbjct: 121 IQLIQRSGGGTSPEGQAAIAIAAERLRRPLARLERH--FAAEDYLVGGRFTVADLNLAET 178 Query: 170 VANAERFKVDLSPYPTISHINKELLALEVFQ 200 + + L P+P ++ + F+ Sbjct: 179 LRYGQAHPALLEPFPAVAAWLDRCQSRPAFR 209 >5N9U-A nrPDB Length = 218 Score = 123 bits (308), Expect = 8e-29, Method: Composition-based stats. Identities = 46/201 (22%), Positives = 82/201 (40%), Gaps = 25/201 (12%) Query: 13 RSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQS 72 RV ++L K I Y+ INL + F ++P +VP +KID + S Sbjct: 19 DCPFCQRVLLSLEEKKIPYKSHLINLGDK-----PQWFLEISPEGKVPVVKIDDKWVADS 73 Query: 73 LAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQ 132 I+ LEE P P L P + A V S I P S +K + ++ + Sbjct: 74 DVIVGILEEKNPEPPL--ATPPEFASV-------GSKIFP----SFVKFLKSKDPNDGTE 120 Query: 133 KVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDLSPYP------TI 186 + + AL+ L+ G + G++++ D+ L P++ + E +P + Sbjct: 121 QALLEELKALDGHLKVH-GPFIAGEKITAVDLSLAPKLYHLEVALGHFKNWPIPDNLTHV 179 Query: 187 SHINKELLALEVFQVSHPRRQ 207 + K L + E F+ + + Sbjct: 180 LNYIKLLFSRESFKKTRAAEE 200 >4MK3-A nrPDB Length = 226 Score = 122 bits (307), Expect = 1e-28, Method: Composition-based stats. Identities = 53/207 (25%), Positives = 89/207 (42%), Gaps = 12/207 (5%) Query: 7 ILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKI-D 65 LY+ S + +VR+ LA K IDYE++ N+ NP+ +VP L + D Sbjct: 24 KLYASQTSPYARKVRVVLAEKKIDYEMIEENVWSPDT-----TIGRFNPLGKVPCLVMED 78 Query: 66 GITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMI--SDLIASGIQPLQNLSVLKQVG 123 G + S I EY + P+ RL+PQ ++R VR L L V ++ Sbjct: 79 GGAVFDSRVIAEYADTLSPVSRLIPQGSRERLEVRCWEALADGLLDAALLARLEVTQRKE 138 Query: 124 QENQMQWAQKVITSGFNALEKILQSTAGK-YCVGDEVSMADVCLVPQVANAERFKVDLS- 181 E W Q+ + AL + A K +C G ++ADV + +A + D++ Sbjct: 139 SERSESWVQRQRSKIDAALTAMSTGLADKTWCTGTHYTLADVAVGCALAYLDFRFPDIAW 198 Query: 182 --PYPTISHINKELLALEVFQVSHPRR 206 +P + +++ + F + P R Sbjct: 199 RDRHPNLVAFQEKIEKRQSFIDTEPPR 225 >3IBH-A nrPDB Length = 233 Score = 122 bits (306), Expect = 1e-28, Method: Composition-based stats. Identities = 50/212 (23%), Positives = 82/212 (38%), Gaps = 20/212 (9%) Query: 5 KPILYSYFRSSCSWRVRIALALKGI--DYEIVPINLIKDGGQQFTEEFQTLNPMKQVPAL 62 K I+Y RVRIALA K + + V INL K G+ EF N VP L Sbjct: 18 KMIIYDTPAGPYPARVRIALAEKNMLSSVQFVRINLWK--GEHKKPEFLAKNYSGTVPVL 75 Query: 63 K-IDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISD-----------LIASGI 110 + DG I + AI EY++ P L + P ++ ++ M++ + Sbjct: 76 ELDDGTLIAECTAITEYIDALDGTPTLTGKTPLEKGVIHMMNKRAELELLDPVSVYFHHA 135 Query: 111 QPLQNLSVLKQVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQV 170 P V +E ++ K + G + + +L+ Y GD SMAD+ ++ + Sbjct: 136 TPGLGPEVELYQNKEWGLRQRDKALH-GMHYFDTVLRER--PYVAGDSFSMADITVIAGL 192 Query: 171 ANAERFKVD-LSPYPTISHINKELLALEVFQV 201 A K+ + K + + Sbjct: 193 IFAAIVKLQVPEECEALRAWYKRMQQRPSVKK 224 >4RI7-A nrPDB Length = 215 Score = 121 bits (304), Expect = 2e-28, Method: Composition-based stats. Identities = 43/210 (20%), Positives = 80/210 (38%), Gaps = 15/210 (7%) Query: 3 AGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPAL 62 A +Y + RV L K + + ++PI+L K G+Q E+ + P QVPA Sbjct: 2 ATPVTIYGPPLCTAVSRVLATLIEKDVPFHLIPIDLSK--GEQKKPEYLKIQPFGQVPAF 59 Query: 63 KIDGITIVQSLAIMEYLEETRPI---PRLLPQDPQKRAIVRMISDLIASGIQP-----LQ 114 K + IT+ +S AI Y+ + L D +A + + P + Sbjct: 60 KDESITLFESRAICRYICDKYADKGNKSLYGTDILSKANIDQWVETDGQTFGPPSGDLVH 119 Query: 115 NLSVLKQVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVP---QVA 171 +L E ++ + + E+ L ++ GDE S AD+ +P + Sbjct: 120 DLLFSSVPVDEALIKKNVDKLAKVLDIYEQKLGQ--TRFLAGDEFSFADLSHLPNGDYLV 177 Query: 172 NAERFKVDLSPYPTISHINKELLALEVFQV 201 N+ + ++ E+ E ++ Sbjct: 178 NSTDKGYLFTSRKNVNRWWTEISNRESWKK 207 >1U3I-A nrPDB Length = 211 Score = 121 bits (303), Expect = 3e-28, Method: Composition-based stats. Identities = 47/219 (21%), Positives = 96/219 (43%), Gaps = 20/219 (9%) Query: 3 AGKPILYSYFRS-SCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPA 61 AG+ I YF + +R+ L G+DYE I+ Q + + P ++PA Sbjct: 2 AGEHIKVIYFDGRGRAESIRMTLVAAGVDYEDERISF------QDWPKIKPTIPGGRLPA 55 Query: 62 LKIDG-----ITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNL 116 +K+ +++SLAI Y+ + + + D + ++ ++I A ++ + Sbjct: 56 VKVTDDHGHVKWMLESLAIARYMAKKHHM--MGETDEEYYSVEKLIGQ--AEDVEHEYHK 111 Query: 117 SVLKQVGQENQ--MQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAE 174 +++K ++ + + + FN + + L+ + GK VGD+V++AD+ L+ + + Sbjct: 112 TLMKPQEEKEKITKEILNGKVPVLFNMICESLKGSTGKLAVGDKVTLADLVLIAVIDHVT 171 Query: 175 RF--KVDLSPYPTISHINKELLALEVFQVSHPRRQPDTP 211 YP I + LLA + +P TP Sbjct: 172 DLDKGFLTGKYPEIHKHRENLLASSPRLAKYLSNRPATP 210 >1V2A-A nrPDB Length = 210 Score = 120 bits (302), Expect = 4e-28, Method: Composition-based stats. Identities = 45/208 (21%), Positives = 80/208 (38%), Gaps = 7/208 (3%) Query: 9 YSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGIT 68 Y S + GI + N+ + LNP +P L +G Sbjct: 4 YYSLISPPCQSAILLAKKLGITLNLKKTNVHDPVE---RDALTKLNPQHTIPTLVDNGHV 60 Query: 69 IVQSLAIMEYLEETR-PIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQ 127 + +S AI+ YL ET L P+DP+ R++V + + + +E Sbjct: 61 VWESYAIVLYLVETYAKDDTLYPKDPKVRSVVNQRLFFDIGTLYKRIIDVIHLVMKKEQP 120 Query: 128 MQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDLSPYPTIS 187 + + + LE+ + A Y D +++AD+CL+ V K DL P+P I Sbjct: 121 SDEQMEKLKGALDLLEQFVTERA--YAAADHLTVADICLLGTVTALNWLKHDLEPFPHIR 178 Query: 188 HINKELLA-LEVFQVSHPRRQPDTPAEL 214 + + A + ++ + DT A + Sbjct: 179 AWLERVRAEMPDYEEFSKQVADDTLAYV 206 >1GWC-A nrPDB Length = 230 Score = 120 bits (300), Expect = 7e-28, Method: Composition-based stats. Identities = 52/214 (24%), Positives = 91/214 (42%), Gaps = 19/214 (8%) Query: 4 GKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMK-QVPAL 62 L + S RV++ALALKG+ YE V +L K +E NP+ ++P L Sbjct: 5 DDLKLLGAWPSPFVTRVKLALALKGLSYEDVEEDLYK-----KSELLLKSNPVHKKIPVL 59 Query: 63 KIDGITIVQSLAIMEYLEETRP--IPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLK 120 +G + +S+ I++Y++E P LLP DP +RAI R + + Sbjct: 60 IHNGAPVCESMIILQYIDEVFASTGPSLLPADPYERAIARFWVAYVDDKLVAPWRQ--WL 117 Query: 121 QVGQENQMQWAQKVITSGFNALEKILQ--STAGKYCVGDEVSMADVCLVPQVANAERFK- 177 + E + +K + LE L+ S G + GD V + DV L ++ + + Sbjct: 118 RGKTEEEKSEGKKQAFAAVGVLEGALRECSKGGGFFGGDGVGLVDVALGGVLSWMKVTEA 177 Query: 178 ------VDLSPYPTISHINKELLALEVFQVSHPR 205 D + P ++ + + L+ + + P Sbjct: 178 LSGDKIFDAAKTPLLAAWVERFIELDAAKAALPD 211 >4PQI-A nrPDB Length = 241 Score = 119 bits (298), Expect = 1e-27, Method: Composition-based stats. Identities = 48/210 (22%), Positives = 87/210 (41%), Gaps = 25/210 (11%) Query: 4 GKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALK 63 G LY+ + + RV I KG+ EI + LI + E + P +VP+L+ Sbjct: 31 GTTKLYTCYTCPFAQRVWITRNFKGLQDEIKLVPLILQNRPAWYPE--KVYPPNKVPSLE 88 Query: 64 IDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRM---ISDLIASGIQPLQNLSVLK 120 +G +SL +++YLE P LLP+DP K+ +D + + K Sbjct: 89 HNGKITGESLDLIKYLESNFEGPSLLPKDPAKKEFAEELFSYTDKFNGTVYTAFKGDLAK 148 Query: 121 QVGQENQMQWAQKVITSGFNALEKIL-QSTAGKYCVGDEVSMADVCLVPQVANAERFKVD 179 + G F+ LE L + G + +G E S+ D+ +P V F ++ Sbjct: 149 EAGP-------------AFDHLENALHKFDDGPFFLGKEFSLVDIAYIPFVERLNIFLLE 195 Query: 180 LSPYPT------ISHINKELLALEVFQVSH 203 + Y ++ +E+ +E ++ + Sbjct: 196 VFKYDITAGRQKLAAWIEEVNKIEAYKQTK 225 >1YQ1-A nrPDB Length = 208 Score = 118 bits (297), Expect = 1e-27, Method: Composition-based stats. Identities = 42/212 (19%), Positives = 91/212 (42%), Gaps = 16/212 (7%) Query: 7 ILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDG 66 L +F +R+ L G+ +E V +N Q + + PMKQ+P L IDG Sbjct: 5 KLTYFFFRGLGEPIRLLFHLAGVQFEEVRMN-----PDQTWLDIKDSTPMKQLPVLNIDG 59 Query: 67 ITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQEN 126 + QS AI+ YL + P++ A V + DL + + + ++ G+ Sbjct: 60 FELPQSGAILRYLARKFG---FAGKTPEEEAWVDAVHDLFKDFLAEFKKFAAERRSGKSA 116 Query: 127 QM------QWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFK-VD 179 + ++ + FN L +L+ + + +G +++ AD+ +V + + + D Sbjct: 117 EEVEKFRSEFFLPARNTYFNILNGLLEKSNSGFLIGSDITFADLVVVDNLLTLKNYGLFD 176 Query: 180 LSPYPTISHINKELLALEVFQVSHPRRQPDTP 211 S + ++ + +++ + + ++P T Sbjct: 177 ESEFTKLAALREKVNSYPGI-KEYIAKRPVTE 207 >3UBL-A nrPDB Length = 242 Score = 117 bits (293), Expect = 4e-27, Method: Composition-based stats. Identities = 45/179 (25%), Positives = 90/179 (50%), Gaps = 13/179 (7%) Query: 7 ILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDG 66 L+ S+ +V++ + KG++YE + I E+F ++PM ++P L++DG Sbjct: 5 KLHGASISNYVNKVKLGILEKGLEYEQIRI------APSQEEDFLKISPMGKIPVLEMDG 58 Query: 67 ITIVQSLAIMEYLEETRP-IPRLLPQDPQKRAIVRMISDLIASGIQ-PLQNLSVLKQVGQ 124 I +S AI+E+L+ P P+L+P+DP + A VR IS +I + + P + + + Sbjct: 59 KFIFESGAILEFLDTIFPQTPKLIPEDPWEAARVREISTIIETYLDIPARRIYLPAAKVS 118 Query: 125 ENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDLSPY 183 ++ + G AL+++++ + Y G+ ++AD A+ +L P+ Sbjct: 119 PEIVEEVHSTLVKGIKALQRVVRFS--PYIAGNVFTLADCS---GFAHLSVLDEELRPF 172 >5A5K-A nrPDB Length = 212 Score = 115 bits (289), Expect = 1e-26, Method: Composition-based stats. Identities = 42/210 (20%), Positives = 83/210 (39%), Gaps = 19/210 (9%) Query: 7 ILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDG 66 ++ + S + RV IAL K +D+E+V + L G+ E F + NP QVPA + Sbjct: 5 KVFGHPASIATRRVLIALHEKNLDFELVHVEL--KDGEHKKEPFLSRNPFGQVPAFEDGD 62 Query: 67 ITIVQSLAIMEYLEETRP--IPRLLPQDPQ---KRAIVRMISDLIASGIQPLQNLSVLKQ 121 + + +S AI +Y+ LL D + + AI+ + + P+ + +Q Sbjct: 63 LKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQ 122 Query: 122 V--------GQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANA 173 + E + + + + E L+ KY G+ ++ D+ +P + Sbjct: 123 IFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKE--FKYLAGETFTLTDLHHIPAIQYL 180 Query: 174 --ERFKVDLSPYPTISHINKELLALEVFQV 201 K + P ++ E+ + Sbjct: 181 LGTPTKKLFTERPRVNEWVAEITKRPASEK 210 >4MPF-A nrPDB Length = 266 Score = 114 bits (285), Expect = 4e-26, Method: Composition-based stats. Identities = 46/191 (24%), Positives = 81/191 (42%), Gaps = 11/191 (5%) Query: 14 SSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSL 73 S S V I GI E+ ++L+K GQ ++EF +N + ++P LK + +S Sbjct: 33 SQPSRAVYIFAKKNGIPLELRTVDLVK--GQHKSKEFLQINSLGKLPTLKDGDFILTESS 90 Query: 74 AIMEYLEETRPIP-RLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQV-GQENQMQWA 131 AI+ YL P P D Q RA V A I+ + + QV G +Q Sbjct: 91 AILIYLSCKYQTPDHWYPSDLQARARVHEYLGWHADCIRGTFGIPLWVQVLGPLIGVQVP 150 Query: 132 QKVITSGFNALEKILQSTAGK------YCVGDEVSMADVCLVPQVANAERFKVDL-SPYP 184 ++ + A+++ LQ K + G +V++AD+ + ++ +L P Sbjct: 151 KEKVERNRTAMDQALQWLEDKFLGDRPFLAGQQVTLADLMALEELMQPVALGYELFEGRP 210 Query: 185 TISHINKELLA 195 ++ + A Sbjct: 211 RLAAWRGRVEA 221 >2AAW-A nrPDB Length = 222 Score = 113 bits (284), Expect = 4e-26, Method: Composition-based stats. Identities = 40/199 (20%), Positives = 82/199 (41%), Gaps = 15/199 (7%) Query: 7 ILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTL-NPMKQVPALKID 65 +LY + + +R+ A GI+Y + D +F + P +QVP L+I Sbjct: 17 VLYYFDARGKAELIRLIFAYLGIEYTDKRFGVNGDAFVEFKNFKKEKDTPFEQVPILQIG 76 Query: 66 GITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQE 125 + + QS AI+ YL + I + + +D+I G+Q + + ++ Sbjct: 77 DLILAQSQAIVRYLSKKYNI-------CGESELNEFYADMIFCGVQDIHYKFNNTNLFKQ 129 Query: 126 NQMQWAQKVITSGFNALEKILQSTAGK------YCVGDEVSMADVCLVPQVANAE-RFKV 178 N+ + + + EK+L+ Y VG+ ++ AD+ + + E ++ Sbjct: 130 NETTFLNEDLPKWSGYFEKLLKKNHTNNNNDKYYFVGNNLTYADLAVFNLYDDIETKYPS 189 Query: 179 DLSPYPTISHINKELLALE 197 L +P + N+ + L Sbjct: 190 SLKNFPLLKAHNEFISNLP 208 >3R2Q-A nrPDB Length = 202 Score = 113 bits (283), Expect = 6e-26, Method: Composition-based stats. Identities = 47/206 (22%), Positives = 80/206 (38%), Gaps = 12/206 (5%) Query: 7 ILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKID- 65 L + S ++ I L KGI +E + + NP+ +VP L + Sbjct: 2 KLVGSYTSPFVRKLSILLLEKGITFEFI-----NELPYNADNGVAQFNPLGKVPVLVTEE 56 Query: 66 GITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQ- 124 G S I EY+E P +LP+DP + VR I + +A GI +SV +Q Sbjct: 57 GECWFDSPIIAEYIELMNVAPAMLPRDPLESLRVRKI-EALADGIMDAGLVSVREQARPA 115 Query: 125 ----ENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDL 180 E+++ ++ I + LE L K + ++A C V + Sbjct: 116 AQQSEDELLRQREKINRSLDVLEGYLVDGTLKTDTVNLATIAIACAVGYLNFRRVAPGWC 175 Query: 181 SPYPTISHINKELLALEVFQVSHPRR 206 P + + + L + E F + P + Sbjct: 176 VDRPHLVKLVENLFSRESFARTEPPK 201 >3PR8-A nrPDB Length = 229 Score = 112 bits (279), Expect = 2e-25, Method: Composition-based stats. Identities = 47/217 (21%), Positives = 93/217 (42%), Gaps = 14/217 (6%) Query: 6 PILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKID 65 LY + S+ V++AL KG+ +E V GGQ + ++P +VP L+ + Sbjct: 3 LKLYGFSVSNYYNMVKLALLEKGLTFEEVTFY----GGQ--APQALEVSPRGKVPVLETE 56 Query: 66 GITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQ-PLQNLSVLKQVGQ 124 + ++ I++Y+E+T+ LLP DP +A VR + I I+ P + G Sbjct: 57 HGFLSETSVILDYIEQTQGGKALLPADPFGQAKVRELLKEIELYIELPARTCYAESFFGM 116 Query: 125 ENQMQWAQKVITSGFNALEKILQSTA-GKYCVGDEVSMADV--CLVPQVANA---ERFKV 178 + +K + ++ Y G+++++AD+ C +ANA + + Sbjct: 117 SVEPLIKEKARADLLAGFATLKRNGRFAPYVAGEQLTLADLMFCFSVDLANAVGKKVLNI 176 Query: 179 D-LSPYPTISHINKELLALEVFQVSHPRRQPDTPAEL 214 D L+ +P + + + ++ PA + Sbjct: 177 DFLADFPQAKALLQLMGENPHMPRILADKEASMPAFM 213 >2CA8-A nrPDB Length = 211 Score = 110 bits (274), Expect = 6e-25, Method: Composition-based stats. Identities = 40/218 (18%), Positives = 88/218 (40%), Gaps = 15/218 (6%) Query: 1 MQAGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVP 60 M + + + +R+ L G++YE I+ Q + + P ++P Sbjct: 1 MTGDHIKVIYFNGRGRAESIRMTLVAAGVNYEDERISF------QDWPKIKPTIPGGRLP 54 Query: 61 ALKIDG-----ITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQN 115 A+KI +V+SLAI Y+ + + + + + + ++I + + Sbjct: 55 AVKITDNHGHVKWMVESLAIARYMAKKHHM--MGGTEEEYYNVEKLIGQAEDLEHEYYKT 112 Query: 116 LSVLKQVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAER 175 L ++ Q+ + + + + + L+++ GK VGD+V++AD+ L+ + + Sbjct: 113 LMKPEEEKQKIIKEILNGKVPVLLDIICESLKASTGKLAVGDKVTLADLVLIAVIDHVTD 172 Query: 176 FKVDL--SPYPTISHINKELLALEVFQVSHPRRQPDTP 211 + YP I + LLA + + TP Sbjct: 173 LDKEFLTGKYPEIHKHRENLLASSPRLAKYLSDRAATP 210 >5NR1-A nrPDB Length = 228 Score = 109 bits (272), Expect = 1e-24, Method: Composition-based stats. Identities = 44/218 (20%), Positives = 85/218 (38%), Gaps = 22/218 (10%) Query: 7 ILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKID- 65 L+ + S +VR+AL K + + + + + EF +LNP P L Sbjct: 6 TLHHFPLDPASRQVRLALGEKRLPFVEMQVRYW-----EMPPEFTSLNPSGMPPVLVETK 60 Query: 66 ---GITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQV 122 + I ++ AI+E++EET P LL +DP +RA R + N +L + Sbjct: 61 HQRNLVICETRAILEHIEETETEPPLLGRDPAERAEARRLLQWFDRKFDNEVNGFLLHEK 120 Query: 123 GQEN----------QMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVAN 172 ++ ++ ++ + +E +LQ+ + G +S+AD ++ Sbjct: 121 MEKRLLRMGAPDLAALRQGREALRMHLGYIESLLQTR--DWLAGRRMSLADFAAAAHLSV 178 Query: 173 AERFK-VDLSPYPTISHINKELLALEVFQVSHPRRQPD 209 + F V + +L + F+ R P Sbjct: 179 IDYFGDVPWKDFQAAKTWYMKLKSRPCFRPILADRWPG 216 >3C8E-A nrPDB Length = 288 Score = 108 bits (271), Expect = 2e-24, Method: Composition-based stats. Identities = 48/230 (20%), Positives = 81/230 (35%), Gaps = 33/230 (14%) Query: 6 PILYSYFRSSCSWRVRIALAL------KGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQV 59 P+ + +V I L G +Y+ I + G QF+ F +NP ++ Sbjct: 44 PLQLYSLGTPNGQKVTIMLEELLALGVTGAEYDAWLIRI--GDGDQFSSGFVEVNPNSKI 101 Query: 60 PALKIDGI----TIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLI-------AS 108 PAL+ + +S +I+ YL E LPQD KR + Sbjct: 102 PALRDHTHNPPIRVFESGSILLYLAEKFG--YFLPQDLAKRTETMNWLFWLQGAAPFLGG 159 Query: 109 GIQPLQNLSVLKQVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVP 168 G + + +K N+ K + + L+K L K+ GDE ++AD+ + P Sbjct: 160 GFGHFYHYAPVKIEYAINRFTMEAKRL---LDVLDKQLAQH--KFVAGDEYTIADMAIWP 214 Query: 169 QVANAERFKV-------DLSPYPTISHINKELLALEVFQVSHPRRQPDTP 211 N V D Y + KE+ + + + P Sbjct: 215 WFGNVVLGGVYDAAEFLDAGSYKHVQRWAKEVGERPAVKRGRIVNRTNGP 264 >5Y7I-A nrPDB Length = 261 Score = 108 bits (269), Expect = 2e-24, Method: Composition-based stats. Identities = 41/215 (19%), Positives = 82/215 (38%), Gaps = 20/215 (9%) Query: 14 SSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSL 73 R+ + L LKG+ + + +++ K + + L P P L +G + Sbjct: 46 CPFCQRLFMVLWLKGVKFTVTTVDMRKKPAE-----LKDLAPGTNPPFLLYNGTLKTDFI 100 Query: 74 AIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASG--------IQPLQNLSVLKQVGQE 125 I E+LE+T PR P + + +D+ A PLQ ++L++ + Sbjct: 101 KIEEFLEQTLAPPRYPHLSPVNKESFDVGADIFAKFSAFIKNSPNNPLQEKNLLREFKRL 160 Query: 126 NQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAE-----RFKVDL 180 + + N++E I S K+ GD +++AD L+P++ ++ Sbjct: 161 DDYLNSPLPEEIDHNSVETITVSNR-KFLDGDRLTLADCNLLPKLHVIRVAAKKYCNFEI 219 Query: 181 -SPYPTISHINKELLALEVFQVSHPRRQPDTPAEL 214 + + K + F+ + P A L Sbjct: 220 PDHFTGVWRYLKNADERDEFKQTCPADIEIEKAYL 254 >5F05-A nrPDB Length = 212 Score = 107 bits (267), Expect = 4e-24, Method: Composition-based stats. Identities = 40/204 (19%), Positives = 75/204 (36%), Gaps = 15/204 (7%) Query: 6 PILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKID 65 L+ S+ + RV L K +++E+V +NL G+ E +LNP QVPA Sbjct: 3 LKLHGSVLSTNTQRVLATLYEKEVEFELVNVNL--GAGEHKQEPHISLNPFGQVPAAVDG 60 Query: 66 GITIVQSLAIMEYLEETRPIPRL-LPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQ 124 + + +S AI +Y+ L A + + ++ + P + V +QV + Sbjct: 61 DLKLFESRAISQYVAHQYASKGTQLGAAGNGYATILVWQEVESHQFDPSASKLVWEQVFK 120 Query: 125 E--------NQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANA--E 174 + + + + E L + KY D ++AD+ +P + Sbjct: 121 PVFGLPTDAALVAETEVTLGKVLDVYEARLSQS--KYLASDSFTLADLHHLPNIQALLGT 178 Query: 175 RFKVDLSPYPTISHINKELLALEV 198 K P +S + Sbjct: 179 PSKKLFDSRPHVSAWVASITGRPA 202 >3RBT-A nrPDB Length = 246 Score = 106 bits (265), Expect = 7e-24, Method: Composition-based stats. Identities = 38/174 (21%), Positives = 65/174 (37%), Gaps = 16/174 (9%) Query: 4 GKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALK 63 K LY + RV + L K I YE+ ++ ++ E F+ NP ++P L+ Sbjct: 25 DKLRLYHVDMNPYGHRVLLVLEAKRIKYEVYRLDPLR-----LPEWFRAKNPRLKIPVLE 79 Query: 64 I----DGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVL 119 I + +S+ I +YL+E L DP +A R++ + I+ Sbjct: 80 IPTDQGDRFLFESVVICDYLDEKYTRHTLHSHDPYVKAQDRLLIERFNELIKGSLECF-- 137 Query: 120 KQVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANA 173 + + + I EK L + Y G+ M D + P V Sbjct: 138 -----DTNFAFGSEQIIQTLEIFEKELTNRGTNYFGGNRPGMLDYMVWPWVERL 186 >4Q5F-A nrPDB Length = 218 Score = 105 bits (261), Expect = 2e-23, Method: Composition-based stats. Identities = 45/211 (21%), Positives = 75/211 (35%), Gaps = 16/211 (7%) Query: 7 ILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDG 66 L + R+ G+ +E ++ + P Q+P L++DG Sbjct: 17 KLTYFDIRGLGEGARLIFHQAGVKFED------NRLKREDWPALKPKTPFGQLPLLEVDG 70 Query: 67 ITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQEN 126 + QS AI YL L + P + A V I D + L+ + +E Sbjct: 71 EVLAQSAAIYRYLGRQFG---LAGKTPMEEAQVDSIFDQFKDFMAELRPCFRVLAGFEEG 127 Query: 127 QMQWAQK-----VITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVD-L 180 + K LEK L + +Y VG V+ AD+ + +A+ E D L Sbjct: 128 DKEKVLKEVAVPARDKHLPLLEKFLAKSGSEYMVGKSVTWADLVITDSLASWESLIPDFL 187 Query: 181 SPYPTISHINKELLALEVFQVSHPRRQPDTP 211 S + + + + L + R P TP Sbjct: 188 SGHLQLKKYIEHVRELPNIKKWIAER-PKTP 217 >4AGS-A nrPDB Length = 471 Score = 104 bits (260), Expect = 3e-23, Method: Composition-based stats. Identities = 44/217 (20%), Positives = 81/217 (37%), Gaps = 24/217 (11%) Query: 1 MQAGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVP 60 M A LY RV I K + Y+ V + L ++ + ++ +NP + VP Sbjct: 22 MAARALKLYVSATCPFCHRVEIVAREKQVSYDRVAVGLR----EEMPQWYKQINPRETVP 77 Query: 61 ALKI---DGITIVQSLAIMEYLEETR-PIPRLLPQDPQKRAIVRMISDLIASGIQPLQNL 116 L++ D + +S+ I +YL+ + P L+ +R + + I L Sbjct: 78 TLEVGNADKRFMFESMLIAQYLDNSGAPAGALMGSSAAQRHQIEFFLAQVGDFIGAAHGL 137 Query: 117 SVLKQVGQENQMQWAQKVITSGFNALEKIL---QSTAGKYCVGDEVSMADVCLVPQVANA 173 ++ +K + ++ +L Q+T YC G E +MADV LVP + Sbjct: 138 L------RDPLSGEKRKAMDDNAAYVDGLLAANQTTGPYYCDG-EFTMADVALVPFLVRL 190 Query: 174 E-----RFKVD-LSPYPTISHINKELLALEVFQVSHP 204 + D P + + + + P Sbjct: 191 KPALMYYAGYDVFCKAPRMKALWAAAAQRASVRETSP 227 Score = 77.0 bits (188), Expect = 6e-15, Method: Composition-based stats. Identities = 44/204 (21%), Positives = 81/204 (39%), Gaps = 25/204 (12%) Query: 2 QAGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPA 61 G +LYS R R+A L+ IV + L E ++ +NP VPA Sbjct: 249 ANGGHVLYSNLFCPFVDRARLASELRKFQMHIVEVPLHPQ-----PEWYKYINPRDTVPA 303 Query: 62 LKI-DGITIVQSLAIMEYLEE-TRPIPRLLPQ-DPQKRAIVRMISDLIASGIQPLQNLSV 118 L G + +S I++Y++ L+P+ D +K V + + L + + Sbjct: 304 LFTPSGEAVHESQLIVQYIDCVATKGSALVPRGDAEKEYEVGFFVENAGYFVGGLMSWII 363 Query: 119 LKQVGQENQMQWAQKVITSGFNALEKILQSTA---GKYCVGDEVSMADVCLVPQVANAER 175 + ++QWA LE+ L G + G ++ DV ++P + A+ Sbjct: 364 RGGEDAKAELQWAA-------GELEQQLAKHPFGEGPFFGGKRMNAGDVAILPFLVRAKA 416 Query: 176 F------KVDL-SPYPTISHINKE 192 F DL + +P ++ + + Sbjct: 417 FMPEFSGGYDLFAHFPLLNGLAEA 440 >2C3Q-A nrPDB Length = 247 Score = 103 bits (256), Expect = 7e-23, Method: Composition-based stats. Identities = 48/209 (22%), Positives = 86/209 (41%), Gaps = 15/209 (7%) Query: 8 LYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGI 67 LY S V I I +E+ ++LIK GQ ++ F +NP+K+VPALK Sbjct: 12 LYLDLLSQPCRAVYIFAKKNDIPFELRIVDLIK--GQHLSDAFAQVNPLKKVPALKDGDF 69 Query: 68 TIVQSLAIMEYLEETRPIP-RLLPQDPQKRAIVRMISDLIA-----SGIQPLQNLSVLKQ 121 T+ +S+AI+ YL +P PQD Q RA V S ++ L + + Sbjct: 70 TLTESVAILLYLTRKYKVPDYWYPQDLQARARVDEYLAWQHTTLRRSCLRALWHKVMFPV 129 Query: 122 VGQENQMQWAQKVITSGFNALEKILQS---TAGKYCVGDEVSMADVCLVPQVANAERFKV 178 E + + ++L+ + G +S+AD+ + ++ + Sbjct: 130 FLGEPVSPQTLAATLAELDVTLQLLEDKFLQNKAFLTGPHISLADLVAITELMHPVGAGC 189 Query: 179 D-LSPYPTISHINKELLA---LEVFQVSH 203 P ++ + + A ++FQ +H Sbjct: 190 QVFEGRPKLATWRQRVEAAVGEDLFQEAH 218 >1N2A-A nrPDB Length = 201 Score = 102 bits (253), Expect = 2e-22, Method: Composition-based stats. Identities = 42/196 (21%), Positives = 83/196 (42%), Gaps = 6/196 (3%) Query: 9 YSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGIT 68 Y +CS I L G D+ +V ++L+K + +++ +NP QVPAL +D T Sbjct: 3 LFYKPGACSLASHITLRESGKDFTLVSVDLMKKRLEN-GDDYFAVNPKGQVPALLLDDGT 61 Query: 69 IV-QSLAIMEYLEETRPIPRLL-PQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQEN 126 ++ + +AIM+YL ++ P +LL P + R + IA+ + + + E Sbjct: 62 LLTEGVAIMQYLADSVPDRQLLAPVNSISRYKTIEWLNYIATELHKGFTP-LFRPDTPEE 120 Query: 127 QMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDLSPYPTI 186 + + + + L+ + G ++AD L + A K++L I Sbjct: 121 YKPTVRAQLEKKLQYVNEALKDEH--WICGQRFTIADAYLFTVLRWAYAVKLNLEGLEHI 178 Query: 187 SHINKELLALEVFQVS 202 + + + Q + Sbjct: 179 AAFMQRMAERPEVQDA 194 >1G6W-A nrPDB Length = 261 Score = 100 bits (249), Expect = 4e-22, Method: Composition-based stats. Identities = 40/238 (16%), Positives = 85/238 (35%), Gaps = 44/238 (18%) Query: 7 ILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDG 66 L+S+ + ++V I L+ G Y + ++ + G+ EF ++NP +VPAL G Sbjct: 22 TLFSHRSAPNGFKVAIVLSELGFHYNTIFLDF--NLGEHRAPEFVSVNPNARVPALIDHG 79 Query: 67 I---TIVQSLAIMEYLEETR----PIPRLLPQDPQKRAIVRMISDLIASGIQPLQ----N 115 + +I +S AI+ +L P L D ++ + SG P+ + Sbjct: 80 MDNLSIWESGAILLHLVNKYYKETGNPLLWSDDLADQSQINAWLFFQTSGHAPMIGQALH 139 Query: 116 LSVLKQVGQENQMQWAQKVITSGFNALEKILQSTAGK----------------------- 152 + ++ + + +E L Sbjct: 140 FRYFHSQKIASAVERYTDEVRRVYGVVEMALAERREALVMELDTENAAAYSAGTTPMSQS 199 Query: 153 -------YCVGDEVSMADVCLVPQVANAERFKVDLS-PYPTISHINKELLALEVFQVS 202 + VGD++++AD+ VP +R +++ +P + K ++ + Sbjct: 200 RFFDYPVWLVGDKLTIADLAFVPWNNVVDRIGINIKIEFPEVYKWTKHMMRRPAVIKA 257 >3BBY-A nrPDB Length = 215 Score = 97.4 bits (241), Expect = 4e-21, Method: Composition-based stats. Identities = 50/209 (23%), Positives = 83/209 (39%), Gaps = 22/209 (10%) Query: 10 SYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITI 69 ++F S +AL KG+ + I I+L D G+ +Q ++VP L+ID + Sbjct: 13 AHFFSPYVLSAWVALQEKGLSFHIKTIDL--DSGEHLQPTWQGYGQTRRVPLLQIDDFEL 70 Query: 70 VQSLAIMEYLEETRPIP---RLLPQDPQKRAIVRMISDLIASGIQPLQNLS----VLKQV 122 +S AI EYLE+ P R+ P D + RA R I + S + P++ V Sbjct: 71 SESSAIAEYLEDRFAPPTWERIYPLDLENRARARQIQAWLRSDLMPIREERPTDVVFAGA 130 Query: 123 GQENQMQWAQKVITSGFNALEKILQ----STAGKYCVGDEVSMADVCLV--PQVANAERF 176 + + F E +L + G++C+ D D+ L+ V + + Sbjct: 131 KKAPLTAEGKASAEKLFAMAEHLLVLGQPNLFGEWCIADT----DLALMINRLVLHGDEV 186 Query: 177 KVDLSPYPTIS---HINKELLALEVFQVS 202 L Y T + +AL Q Sbjct: 187 PERLVDYATFQWQRASVQRFIALSAKQSG 215 >1ZL9-A nrPDB Length = 207 Score = 97.4 bits (241), Expect = 4e-21, Method: Composition-based stats. Identities = 37/212 (17%), Positives = 71/212 (33%), Gaps = 17/212 (8%) Query: 7 ILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTL--NPMKQVPALKI 64 L + R A G YE + Q+ + P Q+P L++ Sbjct: 5 KLTYFNGRGAGEVSRQIFAYAGQQYEDNRV------TQEQWPALKETCAAPFGQLPFLEV 58 Query: 65 DGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQ 124 DG + QS AI +L L + + A V ++D + Sbjct: 59 DGKKLAQSHAIARFLAREFK---LNGKTAWEEAQVNSLADQYKDYSSEARPYFYAVMGFG 115 Query: 125 ENQMQWAQK-----VITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVD 179 ++ +K + L L+++ + VGD ++ D+ + A+ D Sbjct: 116 PGDVETLKKDIFLPAFEKFYGFLVNFLKASGSGFLVGDSLTWIDLAIAQHSADLIAKGGD 175 Query: 180 LSPYPTISHINKELLALEVFQVSHPRRQPDTP 211 S +P + +++ A+ +P TP Sbjct: 176 FSKFPELKAHAEKIQAIPQI-KKWIETRPVTP 206 >4IKH-A nrPDB Length = 244 Score = 96.6 bits (239), Expect = 8e-21, Method: Composition-based stats. Identities = 43/212 (20%), Positives = 81/212 (38%), Gaps = 24/212 (11%) Query: 8 LYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKI--- 64 LYS +V I L G+ YE ++ + Q T EF +++P ++PA+ Sbjct: 25 LYSLPT-PNGVKVSIMLEEIGLPYEAHRVSF--ETQDQMTPEFLSVSPNNKIPAILDPHG 81 Query: 65 -DGITI--VQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVL-- 119 + +S AI+ YL + +LL Q+ R GI P+ Sbjct: 82 PGDQPLALFESGAILIYLADKSG--QLLAQESAARYETIQWLMFQMGGIGPMFGQVGFFN 139 Query: 120 KQVGQENQMQWAQKVITSGFNALEKILQSTAG--KYCVGDEVSMADVCLVPQVANA---- 173 K G+E + + + + L +L G ++ +G+ ++AD+ P + N Sbjct: 140 KFAGREYEDKRPLERYVNEAKRLLGVLDKHLGGREWIMGERYTIADIATFPWIRNLIGFY 199 Query: 174 ---ERFKVDLSPYPTISHINKELLALEVFQVS 202 E +D +P + + + +A Sbjct: 200 EAGELVGID--NFPEVKRVLAKFVARPAVIRG 229 >2PVQ-A nrPDB Length = 201 Score = 96.2 bits (238), Expect = 1e-20, Method: Composition-based stats. Identities = 41/196 (20%), Positives = 73/196 (37%), Gaps = 6/196 (3%) Query: 9 YSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKID-GI 67 Y + S I L+ G+ YE+ ++L K ++ +NP VPAL++ G Sbjct: 3 LYYKVGAASLAPHIILSEAGLPYELEAVDL-KAKKTADGGDYFAVNPRGAVPALEVKPGT 61 Query: 68 TIVQSLAIMEYLEETRPIPRLLPQ-DPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQEN 126 I Q+ AI++Y+ + + P +RA ++ + + E Sbjct: 62 VITQNAAILQYIGDHSDVAAFKPAYGSIERARLQEALGFCSDLHAAFS--GLFAPNLSEE 119 Query: 127 QMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDLSPYPTI 186 I LE +L + GD+ + D + K+DLS YP Sbjct: 120 ARAGVIANINRRLGQLEAMLSDKNAYWL-GDDFTQPDAYASVIIGWGVGQKLDLSAYPKA 178 Query: 187 SHINKELLALEVFQVS 202 + + +LA Q + Sbjct: 179 LKLRERVLARPNVQKA 194 >1GSQ-A nrPDB Length = 202 Score = 92.4 bits (228), Expect = 2e-19, Method: Composition-based stats. Identities = 35/207 (16%), Positives = 74/207 (35%), Gaps = 13/207 (6%) Query: 5 KPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKI 64 K L+ + + R LA G ++ + + + +P L I Sbjct: 2 KYTLHYFPLMGRAELCRFVLAAHGEEFTDRVVEMAD------WPNLKATMYSNAMPVLDI 55 Query: 65 DGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQ 124 DG + QS+ I +L L + ++ V I++ + + + + + Sbjct: 56 DGTKMSQSMCIARHLAREFG---LDGKTSLEKYRVDEITETLQDIFNDVVKIKFAPEAAK 112 Query: 125 ENQMQWAQKVITSGFNALEKILQSTAG--KYCVGDEVSMADVCLVPQVAN-AERFKVDLS 181 E Q +K LE +L S G + VG+ +++AD+ + + L Sbjct: 113 EAVQQNYEKSCKRLAPFLEGLLVSNGGGDGFFVGNSMTLADLHCYVALEVPLKHTPELLK 172 Query: 182 PYPTISHINKELLALEVFQVSHPRRQP 208 P I + K + ++ +++P Sbjct: 173 DCPKIVALRKRVAECPKI-AAYLKKRP 198 >2R5G-A nrPDB Length = 247 Score = 91.2 bits (225), Expect = 3e-19, Method: Composition-based stats. Identities = 38/217 (17%), Positives = 80/217 (36%), Gaps = 34/217 (15%) Query: 14 SSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSL 73 R+ + L LKG+ + + +++ + EE + L P P L + + Sbjct: 30 CPFCQRLFMILWLKGVKFNVTTVDMTRK-----PEELKDLAPGTNPPFLVYNKELKTDFI 84 Query: 74 AIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQK 133 I E+LE+T PR P+ + + +L A ++N Q+ + +K Sbjct: 85 KIEEFLEQTLAPPRYPHLSPKYKESFDVGCNLFAKFSAYIKN-------TQKEANKNFEK 137 Query: 134 VITSGFNALEKILQS----------------TAGKYCVGDEVSMADVCLVPQVANAERF- 176 + F L+ L + + + GD++++AD L+P++ + Sbjct: 138 SLLKEFKRLDDYLNTPLLDEIDPDSAEEPPVSRRLFLDGDQLTLADCSLLPKLNIIKVAA 197 Query: 177 ----KVDL-SPYPTISHINKELLALEVFQVSHPRRQP 208 D+ + + + A E F + P + Sbjct: 198 KKYRDFDIPAEFSGVWRYLHNAYAREEFTHTCPEDKE 234 >1OYJ-A nrPDB Length = 231 Score = 90.8 bits (224), Expect = 4e-19, Method: Composition-based stats. Identities = 44/216 (20%), Positives = 80/216 (37%), Gaps = 23/216 (10%) Query: 5 KPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMK-QVPALK 63 + +L ++ S R RIA+A KG+++E +L ++ NP+ ++P L Sbjct: 6 ELVLLDFWVSPFGQRCRIAMAEKGLEFEYREEDLG-----NKSDLLLRSNPVHRKIPVLL 60 Query: 64 IDGITIVQSLAIMEYLEETRPI-PRLLP-------QDPQKRAIVRMISDLIASGIQPLQN 115 G + +SL I++YL++ P P LLP RA R +D + + + Sbjct: 61 HAGRPVSESLVILQYLDDAFPGTPHLLPPANSGDADAAYARATARFWADYVDRKLYDCGS 120 Query: 116 LSVLKQVGQENQMQWAQKVITSGFNALEKILQST-AGKYCVGDEVSMADVCLVP---QVA 171 + + G+ + + LE L G + DV LVP Sbjct: 121 -RLWRLKGEPQAAAGRE--MAEILRTLEAELGDREFFGGGGGGRLGFVDVALVPFTAWFY 177 Query: 172 NAERFK--VDLSPYPTISHINKELLALEVFQVSHPR 205 + ER P ++ + ++ P Sbjct: 178 SYERCGGFSVEEVAPRLAAWARRCGRIDSVVKHLPS 213 >5F8B-A nrPDB Length = 244 Score = 87.0 bits (214), Expect = 5e-18, Method: Composition-based stats. Identities = 42/228 (18%), Positives = 89/228 (39%), Gaps = 34/228 (14%) Query: 7 ILYSYFRSSCSW-RVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALK-I 64 LY++ C ++ G+D +I T + +++ + +VPA + Sbjct: 5 TLYTFPGDQCRTIAIKAVAKANGLDLDIRETP--------RTPDHLSISKLGKVPAFQGA 56 Query: 65 DGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVG- 123 D + + +AI Y+ LL +D ++ A + + I L +L Q+G Sbjct: 57 DSFKLFECMAIALYITSQNEQTTLLGKDKKEYAEIIKWMSFFNTEIVILMTQQLLPQLGV 116 Query: 124 ---QENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERF---K 177 +Q+++ + + +E+ LQ + VGD++S+AD+ ++ +F K Sbjct: 117 IPYDRDQVEFFANMTQRSVDVVEEYLQDRT--FLVGDQLSLADLFCAGNISLGFQFFYGK 174 Query: 178 VDLSPYPTISHINK---------------ELLALEVFQVSHPRRQPDT 210 P +S + +LL + P ++P+T Sbjct: 175 AWRQQNPNVSRWYEMVCHQPIYAAVTDKFQLLDEPKLTNNPPEKKPET 222 >3FY7-A nrPDB Length = 250 Score = 87.0 bits (214), Expect = 5e-18, Method: Composition-based stats. Identities = 33/168 (19%), Positives = 66/168 (39%), Gaps = 12/168 (7%) Query: 14 SSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSL 73 R+ + L LKG+ + + ++ + + + P Q+P L D +L Sbjct: 42 CPSCQRLFMVLLLKGVPFTLTTVDTRRS-----PDVLKDFAPGSQLPILLYDSDAKTDTL 96 Query: 74 AIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQK 133 I ++LEET P P+ R +D+ ++N + Q+ A Sbjct: 97 QIEDFLEETLGPPDFPSLAPRYRESNTAGNDVFHKFSAFIKNPVPAQDEALYQQLLRALA 156 Query: 134 VITSGFNAL-------EKILQSTAGKYCVGDEVSMADVCLVPQVANAE 174 + S A E L+ + ++ GD +++AD L+P++ + Sbjct: 157 RLDSYLRAPLEHELAGEPQLRESRRRFLDGDRLTLADCSLLPKLHIVD 204 >3KXO-A nrPDB Length = 202 Score = 84.3 bits (207), Expect = 3e-17, Method: Composition-based stats. Identities = 44/204 (21%), Positives = 79/204 (38%), Gaps = 16/204 (7%) Query: 7 ILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDG 66 L + + +R A I YE I Q E ++ P ++P L++DG Sbjct: 8 KLTYFNMRGRAEIIRYIFAYLDIQYEDHRIE------QADWPEIKSTLPFGKIPILEVDG 61 Query: 67 ITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQEN 126 +T+ QSLAI YL + L ++ V I D + + + Q+ Sbjct: 62 LTLHQSLAIARYLTKNTD---LAGNTEMEQCHVDAIVD----TLDDFMSCFPWAEKKQDV 114 Query: 127 QMQWAQKVITSGFNALEKILQS--TAGKYCVGDEVSMADVCLVPQVANAERFKVD-LSPY 183 + Q +++T L + L + ++ +G+ V+ AD FK D L + Sbjct: 115 KEQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNH 174 Query: 184 PTISHINKELLALEVFQVSHPRRQ 207 P + + K++ A+ RR Sbjct: 175 PRLVTLRKKVQAIPAVANWIKRRP 198 >4Q5R-A nrPDB Length = 204 Score = 83.1 bits (204), Expect = 8e-17, Method: Composition-based stats. Identities = 38/208 (18%), Positives = 76/208 (36%), Gaps = 14/208 (6%) Query: 7 ILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDG 66 L + +R L+ D+E + + P + P L+IDG Sbjct: 6 KLTYCPVKALGEPIRFLLSYGEKDFEDYRF------QEGDWPNLKPSMPFGKTPVLEIDG 59 Query: 67 ITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPL--QNLSVLKQVGQ 124 QS+AI YL + L +D + + MI D I+ + + + Q Sbjct: 60 KQTHQSVAISRYLGKQFG---LSGKDDWENLEIDMIVDTISDFRAAIANYHYDADENSKQ 116 Query: 125 ENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERF-KVDL-SP 182 + ++ I ++++++ G Y +++ AD V + K DL + Sbjct: 117 KKWDPLKKETIPYYTKKFDEVVKANGG-YLAAGKLTWADFYFVAILDYLNHMAKEDLVAN 175 Query: 183 YPTISHINKELLALEVFQVSHPRRQPDT 210 P + + +++L L + +R P Sbjct: 176 QPNLKALREKVLGLPAIKAWVAKRPPTD 203 >2WDU-A nrPDB Length = 211 Score = 81.6 bits (200), Expect = 3e-16, Method: Composition-based stats. Identities = 29/215 (13%), Positives = 78/215 (36%), Gaps = 21/215 (9%) Query: 7 ILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDG 66 L+ + + +R+ L G+ +E + + + P +VP L + G Sbjct: 7 KLWYFQFRGRAEPIRLLLTCAGVKFEDYQFTMDQ------WPTIKPTLPGGRVPLLDVTG 60 Query: 67 -----ITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQ 121 +S+AI L ++ + ++ ++ I + + ++ + Sbjct: 61 PDGKLRRYQESMAIARLLARQFK---MMGETDEEYYLIERIIGECEDLYREVY--TIFRT 115 Query: 122 VGQENQMQWAQKVITSG---FNALEKILQSTAGKYCVGDEVSMADVCLVPQVANA--ERF 176 E + + + +G + + L+S+ GK+ G+ +++ D+ L + + Sbjct: 116 PQGEKEAKIKEFKENNGPTLLKLVSESLESSGGKHVAGNRITLGDLFLFTTLTHVMETVP 175 Query: 177 KVDLSPYPTISHINKELLALEVFQVSHPRRQPDTP 211 +P + +K L + +++ TP Sbjct: 176 GFLEQKFPKLHEFHKSLPTSCSRLSEYLKKRAKTP 210 >5D73-A nrPDB Length = 208 Score = 81.2 bits (199), Expect = 3e-16, Method: Composition-based stats. Identities = 28/194 (14%), Positives = 67/194 (34%), Gaps = 14/194 (7%) Query: 7 ILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDG 66 L + + +R+ L +GI + IN ++ Q+P L Sbjct: 4 KLTYFPIRGLAEPIRLVLVDQGIKFTDDRINASD------WPSMKSHFHFGQLPCLYDGD 57 Query: 67 ITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQEN 126 IVQS AI+ +L L + + + M + + + +++ Sbjct: 58 HQIVQSGAILRHLARKH---NLNGGNELETTHIDMFCEGVRDLHTKYTKMIYQAYDTEKD 114 Query: 127 QMQWAQKVITSGFNALEKIL--QSTAGKYCVGDEVSMADVCLVPQVANAERFK-VDLSPY 183 + + ++ EK+L + + +G+++S D L ++ + L + Sbjct: 115 S--YIKDILPVELAKFEKLLATRDDGKNFILGEKISYVDFVLFEELDIHQILDPHCLDKF 172 Query: 184 PTISHINKELLALE 197 P + ++ + Sbjct: 173 PLLKAYHQRMEDRP 186 >2GLR-A nrPDB Length = 209 Score = 80.4 bits (197), Expect = 5e-16, Method: Composition-based stats. Identities = 45/208 (21%), Positives = 81/208 (38%), Gaps = 21/208 (10%) Query: 7 ILYSYFRSSCSWRVRIALALKGIDY--EIVPINLIKDGGQQFTEEFQTLNPMKQVPALKI 64 + + +R+ LA +G + E+V I+ G Q+P + Sbjct: 4 TIVYFPVRGRCEAMRMLLADQGQSWKEEVVTIDTWMQG--LLKPTCL----YGQLPKFED 57 Query: 65 DGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSV-LKQVG 123 +T+ QS AI+ +L + L ++ ++ A D++ G++ L+ V L Sbjct: 58 GDLTLYQSNAILRHLGRSLG---LYGKNQREAAQ----MDMVNDGVEDLRGKYVTLIYTN 110 Query: 124 QENQMQWAQKVITSGFNALEKIL-QSTAGK-YCVGDEVSMADVCLVPQVANAERFKVD-L 180 EN K + E +L Q+ GK + VGD++S AD L+ + + L Sbjct: 111 YENGKNDYVKALPGHLKPFETLLSQNQGGKAFIVGDQISFADYNLLDLLLIHQVLAPGCL 170 Query: 181 SPYPTISHINKELLALEVFQV--SHPRR 206 +P +S L A + S P Sbjct: 171 DNFPLLSAYVARLSARPKIKAFLSSPEH 198 >5Y9Z-A nrPDB Length = 199 Score = 79.7 bits (195), Expect = 8e-16, Method: Composition-based stats. Identities = 41/204 (20%), Positives = 77/204 (37%), Gaps = 16/204 (7%) Query: 7 ILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDG 66 L + + +R A I YE I Q + + P ++P L+++G Sbjct: 5 KLLYFNMRGRAEIIRYIFAYLDIKYEDHRIE------QADWPKIKPTLPFGKIPVLEVEG 58 Query: 67 ITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQEN 126 +T+ QSLAI YL + L + ++ V + D + +L + Q+ Sbjct: 59 LTLHQSLAIARYLTKN---TDLAGKTELEQCQVDAVVD----TLDDFMSLFPWAEENQDL 111 Query: 127 QMQWAQKVITSGFNALEKILQSTAGK--YCVGDEVSMADVCLVPQVANAERFKVD-LSPY 183 + + ++T L K L + G + +G+ V+ AD K D L Y Sbjct: 112 KERTFNDLLTRQAPHLLKDLDTYLGDKEWFIGNYVTWADFYWDICSTTLLVLKPDLLGIY 171 Query: 184 PTISHINKELLALEVFQVSHPRRQ 207 P + + ++ A+ +R Sbjct: 172 PRLVSLRNKVQAIPAISAWILKRP 195 >4K0G-A nrPDB Length = 251 Score = 79.3 bits (194), Expect = 1e-15, Method: Composition-based stats. Identities = 40/210 (19%), Positives = 74/210 (35%), Gaps = 20/210 (9%) Query: 14 SSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSL 73 S S R+ + L LKG+ + + ++ ++ TE Q L P Q+P L + Sbjct: 34 SPFSQRLFMVLWLKGVTFNVTTVD-----TKRRTETVQKLCPGGQLPFLLYGTEVHTDTN 88 Query: 74 AIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQK 133 I E+LE PR D+ A ++N + E + A K Sbjct: 89 KIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALK 148 Query: 134 VITSGF------NALEKILQSTA---GKYCVGDEVSMADVCLVPQVANAERF-----KVD 179 V+ + E + K+ G+E+++AD L+P++ + Sbjct: 149 VLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYRGFT 208 Query: 180 L-SPYPTISHINKELLALEVFQVSHPRRQP 208 + + + A E F + P + Sbjct: 209 IPEAFRGVHRYLSNAYAREEFASTCPDDEE 238 >18GS-A nrPDB Length = 210 Score = 78.5 bits (192), Expect = 2e-15, Method: Composition-based stats. Identities = 43/214 (20%), Positives = 83/214 (38%), Gaps = 24/214 (11%) Query: 7 ILYSYFRSSCSWRVRIALALKGIDY--EIVPINLIKDGGQQFTEEFQTLNPMKQVPALKI 64 + + +R+ LA +G + E+V + ++G + + + Q+P + Sbjct: 5 TVVYFPVRGRCAALRMLLADQGQSWKEEVVTVETWQEGSLKASCLY------GQLPKFQD 58 Query: 65 DGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSV-LKQVG 123 +T+ QS I+ +L T L +D Q+ A+V D++ G++ L+ + L Sbjct: 59 GDLTLYQSNTILRHLGRTLG---LYGKDQQEAALV----DMVNDGVEDLRCKYISLIYTN 111 Query: 124 QENQMQWAQKVITSGFNALEKILQSTAG--KYCVGDEVSMADVCLVPQVANAERFKVD-L 180 E K + E +L G + VGD++S AD L+ + E L Sbjct: 112 YEAGKDDYVKALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCL 171 Query: 181 SPYPTISHINKELLALEVFQVSHPRRQPDTPAEL 214 +P +S L A + +P + Sbjct: 172 DAFPLLSAYVGRLSARPKLKAFL-----ASPEYV 200 >2D2Z-A nrPDB Length = 261 Score = 77.7 bits (190), Expect = 3e-15, Method: Composition-based stats. Identities = 36/211 (17%), Positives = 74/211 (35%), Gaps = 22/211 (10%) Query: 14 SSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSL 73 S R+ + L LKG+ + + ++L + + Q L P P + + Sbjct: 35 CPFSQRLFMILWLKGVVFSVTTVDLKRKPA-----DLQNLAPGTHPPFITFNSEVKTDVN 89 Query: 74 AIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQK 133 I E+LEE P+ L P+ D+ A ++N E + + Sbjct: 90 KIEEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTLQ 149 Query: 134 VITSGF----------NALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDLSPY 183 + N++E I + + K+ G+E+++AD L+P++ + + Sbjct: 150 KLDEYLNSPLPDEIDENSMEDI-KFSTRKFLDGNEMTLADCNLLPKLHIVKVVAKKYRNF 208 Query: 184 ------PTISHINKELLALEVFQVSHPRRQP 208 I + + F + P + Sbjct: 209 DIPKEMTGIWRYLTNAYSRDEFTNTCPSDKE 239 >1M0U-A nrPDB Length = 249 Score = 76.6 bits (187), Expect = 7e-15, Method: Composition-based stats. Identities = 42/214 (19%), Positives = 85/214 (39%), Gaps = 23/214 (10%) Query: 7 ILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDG 66 L+ + + + +R A +YE V + + + PM Q+P L++DG Sbjct: 51 TLFYFNVKALAEPLRYLFAYGNQEYEDVRV------TRDEWPALKPTMPMGQMPVLEVDG 104 Query: 67 ITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQEN 126 + QS+++ +L +T L P + + D++ I + + E+ Sbjct: 105 KRVHQSISMARFLAKTVG---LCGATPWEDLQI----DIVVDTINDFRLKIAVVSYEPED 157 Query: 127 QMQWAQ------KVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERF-KVD 179 +++ + +VI LE+ ++ G +G +++ ADV K D Sbjct: 158 EIKEKKLVTLNAEVIPFYLEKLEQTVKDNDGHLALG-KLTWADVYFAGITDYMNYMVKRD 216 Query: 180 -LSPYPTISHINKELLALEVFQVSHPRRQPDTPA 212 L PYP + + + ALE + ++P T Sbjct: 217 LLEPYPALRGVVDAVNALEPI-KAWIEKRPVTEV 249 >2GSR-A nrPDB Length = 207 Score = 75.8 bits (185), Expect = 1e-14, Method: Composition-based stats. Identities = 35/203 (17%), Positives = 76/203 (37%), Gaps = 19/203 (9%) Query: 10 SYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITI 69 + +R+ LA + ++ + + + + +Q+P + +T+ Sbjct: 7 YFPVRGRCEAMRMLLADQDQSWKEEVVTM------ETWPPLKPSCLFRQLPKFQDGDLTL 60 Query: 70 VQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQ-NLSVLKQVGQENQM 128 QS AI+ +L + L +D ++ A+V D++ G++ L+ + L E Sbjct: 61 YQSNAILRHLGRSFG---LYGKDQKEAALV----DMVNDGVEDLRCKYATLIYTNYEAGK 113 Query: 129 QWAQKVITSGFNALEKILQST--AGKYCVGDEVSMADVCLVPQVANAERFKVD-LSPYPT 185 + K + E +L + VG ++S AD L+ + + L +P Sbjct: 114 EKYVKELPEHLKPFETLLSQNQGGQAFVVGSQISFADYNLLDLLRIHQVLNPSCLDAFPL 173 Query: 186 ISHINKELLALEVFQV--SHPRR 206 +S L A + + P Sbjct: 174 LSAYVARLSARPKIKAFLASPEH 196 >1TU7-A nrPDB Length = 208 Score = 75.4 bits (184), Expect = 2e-14, Method: Composition-based stats. Identities = 33/198 (16%), Positives = 73/198 (36%), Gaps = 18/198 (9%) Query: 7 ILYSYFRSSCSWRVRIALALKGIDYEIVPIN--LIKDGGQQFTEEFQTLNPMKQVPALKI 64 L + + +R+ L +D +I I+ + KD +FQ Q+P L Sbjct: 4 KLTYFSIRGLAEPIRLFL----VDQDIKFIDDRIAKDDFSSIKSQFQ----FGQLPCLYD 55 Query: 65 DGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQ 124 IVQS AI+ +L L ++ + + M + + + + + Sbjct: 56 GDQQIVQSGAILRHLARKY---NLNGENEMETTYIDMFCEGVRDLHVKYTRMIYMAYETE 112 Query: 125 ENQMQWAQKVITSGFNALEKIL--QSTAGKYCVGDEVSMADVCLVPQVANAERFK-VDLS 181 ++ + + ++ EK+L + +GD++S AD L ++ + L Sbjct: 113 KD--PYIKSILPGELAKFEKLLATRGNGRNLILGDKISYADYALFEELDVHQILDPHCLD 170 Query: 182 PYPTISHINKELLALEVF 199 +P + ++ + Sbjct: 171 KFPLLKVFHQRMKDRPKL 188 >2HNL-A nrPDB Length = 225 Score = 74.3 bits (181), Expect = 3e-14, Method: Composition-based stats. Identities = 37/198 (18%), Positives = 76/198 (38%), Gaps = 12/198 (6%) Query: 2 QAGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPA 61 Q K L + + +R+ AL + YE I + + + P VP Sbjct: 24 QMEKYTLTYFNGRGRAEVIRLLFALANVSYEDNRI------TRDEWKYLKPRTPFGHVPM 77 Query: 62 LKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQ 121 L + G + +S AI LL + + A + + I Q L + K Sbjct: 78 LNVSGNVLGESHAIEL---LLGGRFGLLGTNDWEEAKIMAVVLNIDELFQKLIPWTHEKN 134 Query: 122 VGQENQM--QWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVD 179 ++ ++ ++ + EK L+ + + VG++VS+AD+ + + + +V Sbjct: 135 TTKKAELFRNLSESDVMPFLGRYEKFLKESTTGHIVGNKVSVADLTVFNMLMTLDD-EVK 193 Query: 180 LSPYPTISHINKELLALE 197 L YP ++ ++ + Sbjct: 194 LEEYPQLASFVNKIGQMP 211 >5AN1-A nrPDB Length = 219 Score = 73.9 bits (180), Expect = 5e-14, Method: Composition-based stats. Identities = 30/209 (14%), Positives = 64/209 (30%), Gaps = 20/209 (9%) Query: 6 PILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMK----QVPA 61 P+L + + +R+ L G ++E + +E + +P Sbjct: 3 PVLGYWKTRALCQPIRLMLGYTGTEFEEKNYPVGDAPDYDKSEWLAVKFKLGLAFPNLPY 62 Query: 62 LKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQ 121 + I QS AIM YL L P++ MI + + ++ Sbjct: 63 YIDGDVKITQSKAIMRYLARKHG---LCGTTPEELVRTDMIECQLTDMHEAFFTVTYEHY 119 Query: 122 VGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVD-- 179 ++ + + L + + GD+++ D + +D Sbjct: 120 EQKDAYTASLPAKLRQYSDFL------GSRPWFAGDKLTYIDFLAYEIFD--QHLSLDRT 171 Query: 180 -LSPYPTISHINKELLALEVFQV--SHPR 205 L + + K LE + + P+ Sbjct: 172 CLDGFKNLQAFQKRFEDLEAIKKYMASPK 200 >2DC5-A nrPDB Length = 231 Score = 73.5 bits (179), Expect = 6e-14, Method: Composition-based stats. Identities = 35/206 (16%), Positives = 67/206 (32%), Gaps = 21/206 (10%) Query: 2 QAGKPILYSYFR-SSCSWRVRIALALKGIDYEIVPINLIK----DGGQQFTEEFQTLNPM 56 +G P+ Y+ + +R+ L YE + D Q E+F+ Sbjct: 5 SSGMPMTLGYWDIRGLAHAIRLFLEYTDSSYEEKRYTMGDAPDYDQSQWLNEKFKLGLDF 64 Query: 57 KQVPALKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNL 116 +P L I QS AI+ YL L + ++R V ++ Q + N Sbjct: 65 PNLPYLIDGSHKITQSNAILRYLGRKH---NLCGETEEERIRVDIL------ENQLMDNR 115 Query: 117 SVLKQVGQENQMQWAQKVITSGFN----ALEKILQSTAGKYCVGDEVSMADVCLVPQVAN 172 VL ++ + + + L + GD+++ D + Sbjct: 116 MVLARLCYNADFEKLKPGYLEQLPGMMRLYSEFLGKR--PWFAGDKITFVDFIAYDVLER 173 Query: 173 AERFKVD-LSPYPTISHINKELLALE 197 + F+ L +P + L+ Sbjct: 174 NQVFEAKCLDAFPNLKDFIARFEGLK 199 >2FHE-A nrPDB Length = 216 Score = 73.1 bits (178), Expect = 9e-14, Method: Composition-based stats. Identities = 40/198 (20%), Positives = 70/198 (35%), Gaps = 10/198 (5%) Query: 6 PILYSYFR-SSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKI 64 P Y++ VR+ L G YE I DG + F+++F+ + +P Sbjct: 1 PAKLGYWKIRGLQQPVRLLLEYLGEKYEE-QIYERDDGEKWFSKKFELGLDLPNLPYYID 59 Query: 65 DGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQ 124 D + QSLAI+ Y+ + ++ ++RA V MI Q + +S + Sbjct: 60 DKCKLTQSLAILRYIADKHG---MIGTTSEERARVSMIEGAAVDLRQGISRISYQPKF-- 114 Query: 125 ENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERF-KVDLSPY 183 E + K + + L Y G VS D + + L + Sbjct: 115 EQLKEGYLKDLPTTMKMWSDFL--GKNPYLRGTSVSHVDFMVYEALDAIRYLEPHCLDHF 172 Query: 184 PTISHINKELLALEVFQV 201 P + + AL + Sbjct: 173 PNLQQFMSRIEALPSIKA 190 >5FWG-A nrPDB Length = 217 Score = 70.4 bits (171), Expect = 5e-13, Method: Composition-based stats. Identities = 36/198 (18%), Positives = 65/198 (32%), Gaps = 13/198 (6%) Query: 6 PILYSYFR-SSCSWRVRIALALKGIDYEIVPINLIK----DGGQQFTEEFQTLNPMKQVP 60 P++ Y+ + +R+ L YE + D Q E+F+ +P Sbjct: 1 PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLP 60 Query: 61 ALKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLK 120 L I QS AIM YL L + ++R ++ + + +Q + + Sbjct: 61 YLIDGSRKITQSNAIMRYLARKHH---LCGETEEERIRADIVENQVMD--NRMQLIMLCY 115 Query: 121 QVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVD- 179 E Q K I + L + GD+V+ D + F+ Sbjct: 116 NPDFEKQKPEFLKTIPEKMKLYSEFLGKR--PWFAGDKVTYVDFLAYDILDQYHIFEPKC 173 Query: 180 LSPYPTISHINKELLALE 197 L +P + L+ Sbjct: 174 LDAFPNLKDFLARFEGLK 191 >1B4P-A nrPDB Length = 217 Score = 69.7 bits (169), Expect = 9e-13, Method: Composition-based stats. Identities = 34/198 (17%), Positives = 65/198 (32%), Gaps = 13/198 (6%) Query: 6 PILYSYFR-SSCSWRVRIALALKGIDYEIVPINLIK----DGGQQFTEEFQTLNPMKQVP 60 P++ Y+ + +R+ L YE + D Q E+F+ +P Sbjct: 1 PMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLP 60 Query: 61 ALKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLK 120 L I QS AIM YL L + ++R V ++ + LQ V Sbjct: 61 YLIDGSRKITQSNAIMRYLARKHH---LCGETEEERIRVDVLENQAMDT--RLQLAMVCY 115 Query: 121 QVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVD- 179 E + + + + L + G++++ D + + F+ Sbjct: 116 SPDFERKKPEYLEGLPEKMKLYSEFL--GKQPWFAGNKITYVDFLVYDVLDQHRIFEPKC 173 Query: 180 LSPYPTISHINKELLALE 197 L +P + L+ Sbjct: 174 LDAFPNLKDFVARFEGLK 191 >1XWK-A nrPDB Length = 218 Score = 69.3 bits (168), Expect = 1e-12, Method: Composition-based stats. Identities = 30/200 (15%), Positives = 67/200 (33%), Gaps = 17/200 (8%) Query: 6 PILYSYFR-SSCSWRVRIALALKGIDYEIVPINLIK----DGGQQFTEEFQTLNPMKQVP 60 P++ Y+ + +R+ L YE + D Q E+F+ +P Sbjct: 2 PMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLP 61 Query: 61 ALKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNL--SV 118 L I QS AI+ Y+ L + +++ V ++ + L + + Sbjct: 62 YLIDGAHKITQSNAILCYIARKH---NLCGETEEEKIRVDILENQTMDNHMQLGMICYNP 118 Query: 119 LKQVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKV 178 + + ++ + + L K + G++++ D + + F+ Sbjct: 119 EFEKLKPKYLEELPEKLKLYSEFLGKR------PWFAGNKITFVDFLVYDVLDLHRIFEP 172 Query: 179 D-LSPYPTISHINKELLALE 197 L +P + LE Sbjct: 173 KCLDAFPNLKDFISRFEGLE 192 >4Q5Q-A nrPDB Length = 219 Score = 69.3 bits (168), Expect = 1e-12, Method: Composition-based stats. Identities = 28/211 (13%), Positives = 66/211 (31%), Gaps = 12/211 (5%) Query: 5 KPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMK----QVP 60 +PIL + + +R+ L G+D+ + +E + +P Sbjct: 3 QPILGYWDIRGYAQPIRLLLTYSGVDFVDKRYQIGPAPDFDRSEWLNEKFNLGLDFPNLP 62 Query: 61 ALKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLK 120 + + Q+ AI+ YL L + + +R+ + + V Sbjct: 63 YYIDGDMKMTQTFAILRYLGRKYK---LNGSNDHE--EIRISMAEQQTEDMMAAMIRVCY 117 Query: 121 QVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVD- 179 + K + + K + A + G +S D L + + + + Sbjct: 118 DANCDKLKPDYLKSLPDCLKLMSKFVGEHA--FIAGANISYVDFNLYEYLCHVKVMVPEV 175 Query: 180 LSPYPTISHINKELLALEVFQVSHPRRQPDT 210 + + + + +L ++QP T Sbjct: 176 FGQFENLKRYVERMESLPRVSDYIKKQQPKT 206 >1HNA-A nrPDB Length = 217 Score = 68.5 bits (166), Expect = 2e-12, Method: Composition-based stats. Identities = 31/198 (15%), Positives = 62/198 (31%), Gaps = 13/198 (6%) Query: 6 PILYSYFR-SSCSWRVRIALALKGIDYEIVPINLIK----DGGQQFTEEFQTLNPMKQVP 60 P+ Y+ + +R+ L YE + D Q E+F+ +P Sbjct: 1 PMTLGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLP 60 Query: 61 ALKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLK 120 L I QS AI+ Y+ L + +++ ++ + L L Sbjct: 61 YLIDGTHKITQSNAILRYIARKH---NLCGESEKEQIREDILENQFMDSRMQLAKLCYDP 117 Query: 121 QVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVD- 179 E + + + L + +GD+++ D + + F+ Sbjct: 118 DF--EKLKPEYLQALPEMLKLYSQFL--GKQPWFLGDKITFVDFIAYDVLERNQVFEPSC 173 Query: 180 LSPYPTISHINKELLALE 197 L +P + LE Sbjct: 174 LDAFPNLKDFISRFEGLE 191 >4GTU-A nrPDB Length = 217 Score = 65.4 bits (158), Expect = 2e-11, Method: Composition-based stats. Identities = 35/214 (16%), Positives = 65/214 (30%), Gaps = 14/214 (6%) Query: 9 YSYFR-SSCSWRVRIALALKGIDYEIVPINLIK----DGGQQFTEEFQTLNPMKQVPALK 63 Y+ + +R+ L YE + D Q E+F+ +P L Sbjct: 4 LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 63 Query: 64 IDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVG 123 I QS AI+ Y+ L + +++ V ++ + L V Sbjct: 64 DGAHKITQSNAILCYIARKH---NLCGETEEEKIRVDILENQAMDVSNQLAR--VCYSPD 118 Query: 124 QENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVD-LSP 182 E + + + + L + VGD+++ D + F+ + L Sbjct: 119 FEKLKPEYLEELPTMMQHFSQFLGKR--PWFVGDKITFVDFLAYDVLDLHRIFEPNCLDA 176 Query: 183 YPTISHINKELLALEVFQVS-HPRRQPDTPAELR 215 +P + LE R P R Sbjct: 177 FPNLKDFISRFEGLEKISAYMKSSRFLPKPLYTR 210 >4FQU-A nrPDB Length = 313 Score = 65.0 bits (157), Expect = 2e-11, Method: Composition-based stats. Identities = 49/237 (20%), Positives = 91/237 (38%), Gaps = 42/237 (17%) Query: 4 GKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIK----DGGQQFTEE---------- 49 G+ LY+ F + RV I ALKG++ E++ ++++ + G F Sbjct: 43 GRYHLYAGFACPWAHRVLIMRALKGLE-EMISVSMVNAYMGENGWTFLPGDDVVPDSING 101 Query: 50 -------FQTLNPMKQ----VPAL--KIDGITIV-QSLAIMEYLEETRPIPRLLPQDPQK 95 + +P +P L K++ + +S I+ L LP D Sbjct: 102 ADYLYQVYTAADPTYTGRVTIPILWDKVEKRILNNESSEIIRILNSAFDDVGALPGD-YY 160 Query: 96 RAIVRMISDLIASGIQPLQNLSVLK--QVGQENQMQWAQKVITSGFNALEKILQSTAGKY 153 A R D I + + N V + + + A + + LE+ L ++ Sbjct: 161 PAEFRPEIDRINARVYETLNNGVYRSGFATTQEAYEEAFYPLFDTLDWLEEHLTGR--EW 218 Query: 154 CVGDEVSMADVCLVPQVANAE-----RFKVDL---SPYPTISHINKELLALEVFQVS 202 VGD ++ AD+ L P + + FK +L + YP +S + +L + E + Sbjct: 219 LVGDRLTEADIRLFPTLVRFDAIYHGHFKCNLRRIADYPNLSRLVGKLASHERVAPT 275 >2WRT-A nrPDB Length = 218 Score = 63.1 bits (152), Expect = 9e-11, Method: Composition-based stats. Identities = 27/164 (16%), Positives = 56/164 (34%), Gaps = 8/164 (4%) Query: 39 IKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAI 98 D + ++F + +P D + QS+AIM Y+ + +L P++RA Sbjct: 35 RDDREKWLGDKFNMGLDLPNLPYYIDDKCKLTQSVAIMRYIADKHG---MLGSTPEERAR 91 Query: 99 VRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDE 158 + MI + A ++ +E + + ++ + + L Y G Sbjct: 92 ISMI-EGAAMDLRMGFVRVCYNPKFEEVKGDYLKE-LPTTLKMWSNFLGDRH--YLTGSS 147 Query: 159 VSMADVCLVPQVANAERFKVD-LSPYPTISHINKELLALEVFQV 201 VS D + + L +P + + L + Sbjct: 148 VSHVDFMVYEALDCIRYLAPQCLEDFPKLKEFKSRIEDLPKIKA 191 >3PPU-A nrPDB Length = 352 Score = 62.7 bits (151), Expect = 1e-10, Method: Composition-based stats. Identities = 40/238 (16%), Positives = 82/238 (34%), Gaps = 55/238 (23%) Query: 4 GKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIK----------------------- 40 G+ LY + + R I LKG++ + + + ++ Sbjct: 76 GRYHLYVSYACPWATRTLIVRKLKGLE-DFIGVTVVSPRMGSNGWPFANVDPFPAADSDP 134 Query: 41 -DGGQQFTEEFQTLNP----MKQVPAL--KIDGITIV-QSLAIME--------YLEETRP 84 + Q + + + P VP L K G + +S I+ L E + Sbjct: 135 LNNAQHVKDLYLKVKPDYDGRFTVPVLWDKHTGTIVNNESSEIIRMFNTAFNHLLPEDKA 194 Query: 85 IPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQKVITSGFNALEK 144 L P+ RA + ++D + + + + + A + + LEK Sbjct: 195 KLDLYPESL--RAKIDEVNDWVYDTVN--NGVYKSGFASTQKAYEAAVIPLFESLDRLEK 250 Query: 145 ILQSTAGKYCVGDEVSMADVCLVPQVANAE-----RFKVDLSP----YPTISHINKEL 193 +L+ Y +G +++ AD+ L + + FK +L YP + ++L Sbjct: 251 MLE--GQDYLIGGQLTEADIRLFVTIVRFDPVYVTHFKCNLRTIRDGYPNLHRWMRKL 306 >1FHE-A nrPDB Length = 217 Score = 62.7 bits (151), Expect = 1e-10, Method: Composition-based stats. Identities = 32/170 (18%), Positives = 59/170 (34%), Gaps = 8/170 (4%) Query: 39 IKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAI 98 D + +E+F + +P D + QS+AIM Y+ + +L P++RA Sbjct: 34 RDDREKWMSEKFNMGLDLPNLPYYIDDKCKLTQSVAIMRYIADKHG---MLGTTPEERAR 90 Query: 99 VRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDE 158 + MI + A ++ + V E + K + L Y G Sbjct: 91 ISMI-EGAAMDLR-IGFGRVCYNPKFEEVKEEYVKELPKTLKMWSDFLGDRH--YLTGSS 146 Query: 159 VSMADVCLVPQVANAERF-KVDLSPYPTISHINKELLALEVFQVSHPRRQ 207 VS D L + + L +P + + AL + ++ Sbjct: 147 VSHVDFMLYETLDSIRYLAPHCLDEFPKLKEFKSRIEALPKIKAYMESKR 196 >3GTU-B nrPDB Length = 224 Score = 62.3 bits (150), Expect = 1e-10, Method: Composition-based stats. Identities = 30/205 (14%), Positives = 64/205 (31%), Gaps = 23/205 (11%) Query: 8 LYSYFR-SSCSWRVRIALALKGIDYEIVPINLIK----DGGQQFTEEFQTLNPMKQVPAL 62 + Y+ + +R+ L YE + D Q +F+ +P L Sbjct: 7 VLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYL 66 Query: 63 KIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQV 122 I QS AI+ Y+ + + +++ V D+I + + + + Sbjct: 67 LDGKNKITQSNAILRYIARKH---NMCGETEEEKIRV----DIIENQVMDFRTQLIRLCY 119 Query: 123 GQENQMQWAQKVITSGFNALEKILQS-----TAGKYCVGDEVSMADVCLVPQVANAERFK 177 +++ K+ L L+ + G++++ D + F Sbjct: 120 SSDHE-----KLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFD 174 Query: 178 VD-LSPYPTISHINKELLALEVFQV 201 L +P + ALE Sbjct: 175 PKCLDEFPNLKAFMCRFEALEKIAA 199 >1B8X-A nrPDB Length = 280 Score = 62.3 bits (150), Expect = 2e-10, Method: Composition-based stats. Identities = 26/160 (16%), Positives = 56/160 (35%), Gaps = 8/160 (5%) Query: 39 IKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAI 98 +G + ++F+ +P + + QS+AI+ Y+ + +L P++RA Sbjct: 34 RDEGDKWRNKKFELGLEFPNLPYYIDGDVKLTQSMAIIRYIADKH---NMLGGCPKERAE 90 Query: 99 VRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDE 158 + M+ + + ++ K + + E L Y GD Sbjct: 91 ISMLEGAVLDIRYGVSRIAYSKDFETLKVDFLS--KLPEMLKMFEDRLCHKT--YLNGDH 146 Query: 159 VSMADVCLVPQVANAERFK-VDLSPYPTISHINKELLALE 197 V+ D L + + L +P + K + A+ Sbjct: 147 VTHPDFMLYDALDVVLYMDPMCLDAFPKLVCFKKRIEAIP 186 >1BG5-A nrPDB Length = 254 Score = 62.0 bits (149), Expect = 2e-10, Method: Composition-based stats. Identities = 26/160 (16%), Positives = 56/160 (35%), Gaps = 8/160 (5%) Query: 39 IKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAI 98 +G + ++F+ +P + + QS+AI+ Y+ + +L P++RA Sbjct: 35 RDEGDKWRNKKFELGLEFPNLPYYIDGDVKLTQSMAIIRYIADKH---NMLGGCPKERAE 91 Query: 99 VRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDE 158 + M+ + + ++ K + + E L Y GD Sbjct: 92 ISMLEGAVLDIRYGVSRIAYSKDFETLKVDFLS--KLPEMLKMFEDRLCHKT--YLNGDH 147 Query: 159 VSMADVCLVPQVANAERFK-VDLSPYPTISHINKELLALE 197 V+ D L + + L +P + K + A+ Sbjct: 148 VTHPDFMLYDALDVVLYMDPMCLDAFPKLVCFKKRIEAIP 187 >1DUG-A nrPDB Length = 234 Score = 62.0 bits (149), Expect = 2e-10, Method: Composition-based stats. Identities = 26/160 (16%), Positives = 56/160 (35%), Gaps = 8/160 (5%) Query: 39 IKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAI 98 +G + ++F+ +P + + QS+AI+ Y+ + +L P++RA Sbjct: 34 RDEGDKWRNKKFELGLEFPNLPYYIDGDVKLTQSMAIIRYIADKH---NMLGGCPKERAE 90 Query: 99 VRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDE 158 + M+ + + ++ K + + E L Y GD Sbjct: 91 ISMLEGAVLDIRYGVSRIAYSKDFETLKVDFLS--KLPEMLKMFEDRLCHKT--YLNGDH 146 Query: 159 VSMADVCLVPQVANAERFK-VDLSPYPTISHINKELLALE 197 V+ D L + + L +P + K + A+ Sbjct: 147 VTHPDFMLYDALDVVLYMDPMCLDAFPKLVCFKKRIEAIP 186 >3IR4-A nrPDB Length = 218 Score = 57.3 bits (137), Expect = 5e-09, Method: Composition-based stats. Identities = 37/193 (19%), Positives = 79/193 (40%), Gaps = 14/193 (7%) Query: 3 AGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPAL 62 + LY Y + R+ LK I E+ N++++ + + K VP L Sbjct: 1 SNAMKLYIYDHCPFCVKARMIFGLKNIPVEL---NVLQNDDEATP---TRMIGQKMVPIL 54 Query: 63 K-IDGITIVQSLAIMEYLEETRPIPRLLPQ-DPQKRAIVRMISDLIASGIQPLQNLSVLK 120 + D + +S+ I+ Y++ P L + +P +R ++ + + P S Sbjct: 55 QKDDSRYLPESMDIVHYVDNLDGKPLLTGKRNPAIEEWLRKVNGYVNQLLLPRFAKSAFD 114 Query: 121 QVGQENQMQWAQKVITSGFNALEKILQSTAG---KYCVGDEVSMADVCLV-PQVANAERF 176 + Q+ + + + + L +AG K +GD++ + D +V P N E Sbjct: 115 EFSTPAARQYFIRKKEASSGSFDNHLAHSAGLIKK--IGDDLRLLDKLIVQPNAVNGELS 172 Query: 177 KVDLSPYPTISHI 189 + D+ +P + ++ Sbjct: 173 EDDIHLFPLLRNL 185 >1GSU-A nrPDB Length = 219 Score = 56.9 bits (136), Expect = 6e-09, Method: Composition-based stats. Identities = 26/202 (12%), Positives = 63/202 (31%), Gaps = 16/202 (7%) Query: 6 PILYSYFR-SSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMK----QVP 60 + Y+ + +R+ L Y+ ++ + +P Sbjct: 1 VVTLGYWDIRGLAHAIRLLLEYTETPYQERRYKAGPAPDFDPSDWTNEKEKLGLDFPNLP 60 Query: 61 ALKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLK 120 L + + QS AI+ Y+ + + ++ V ++ + + L Sbjct: 61 YLIDGDVKLTQSNAILRYIARKH---NMCGETEVEKQRVDVLENHLMDLRMAFARLCYSP 117 Query: 121 QVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDL 180 E + + L + L S + + VGD+++ D + F D Sbjct: 118 DF--EKLKPAYLEQLPGKLRQLSRFLGSRS--WFVGDKLTFVDFLAYDVLDQQRMFVPDC 173 Query: 181 SPYPTIS-HINKELLALEVFQV 201 P + ++++ L E + Sbjct: 174 ---PELQGNLSQFLQRFEALEK 192 >4LMW-A nrPDB Length = 251 Score = 56.2 bits (134), Expect = 9e-09, Method: Composition-based stats. Identities = 41/227 (18%), Positives = 73/227 (32%), Gaps = 41/227 (18%) Query: 14 SSCSWRVRIALALKGIDY--EIVPINLIKDGGQQFTEEFQTLNPMK----QVPALKIDGI 67 +W+ R L KG+ Y E V I+ +Q P +P ++ Sbjct: 22 GPNTWKTRYVLNFKGLKYRTEWVEYPDIEAVCKQIGAPATEKKPDGRDHYTLPVIQDPNT 81 Query: 68 T--IVQSLAIMEYLEETRPI-PRLLPQDPQKRAIVRMISDLIASGIQPLQNLSV------ 118 + S AI +YLE T P PRL P+ + S + P+ N+ V Sbjct: 82 KAVVADSDAIAKYLESTYPDTPRLFPEGTRAFQHA-FYQLARPSVLMPIFNIVVARVWKL 140 Query: 119 ----------------LKQVGQENQMQWAQKVITSGFNALEKILQSTAGK---YCVGDEV 159 L + +E + + SG ++ L++ +GD V Sbjct: 141 LRPRSQEYFRATREQMLGKKLEEIGSEDDWNALESGLARIKSSLEANGAGKDLLLMGDRV 200 Query: 160 SMADVCLVPQVANAERFKV----DLSPYPTISH--INKELLALEVFQ 200 + AD+ L D + ++ K + ++ Sbjct: 201 TFADLQLASLFIWLRVSAGEESEDWKRFLSLHEGKWAKFMQQFAAYE 247 >6GC9-A nrPDB Length = 327 Score = 55.8 bits (133), Expect = 1e-08, Method: Composition-based stats. Identities = 41/238 (17%), Positives = 79/238 (33%), Gaps = 55/238 (23%) Query: 4 GKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKD---------------------- 41 G+ LY + + R I +KG++ E + ++++ Sbjct: 47 GRYHLYVSYACPWATRTLIVRKIKGLE-EFIDVSVVSPRMGAHGWPFANVDAFPGADADP 105 Query: 42 --GGQQFTEEFQTLNP----MKQVPAL---KIDGITIVQSLAIMEYLEETRPIP------ 86 G + + + +NP VP L K I +S I+ Sbjct: 106 LFGAEHVKDLYMRVNPDYEGRFTVPILWDKKTSAIVNNESSEIIRMFNTAFNDQLPSDKA 165 Query: 87 --RLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQKVITSGFNALEK 144 L P+ R + I++ + + + + + A + + LEK Sbjct: 166 AIDLYPEAL--RGEIDGINEWVYDTVN--NGVYKSGFATSQKAYEAAVVPLFESLDRLEK 221 Query: 145 ILQSTAGKYCVGDEVSMADVCLVPQVANAE-----RFKVDLSP----YPTISHINKEL 193 IL Y VGD+++ AD+ L + + FK ++ YP I ++L Sbjct: 222 ILTGK--DYLVGDQLTEADIRLFVTIVRFDPVYVGHFKCNIRTIRDGYPAIDLWMRKL 277 >1G7O-A nrPDB Length = 215 Score = 54.6 bits (130), Expect = 3e-08, Method: Composition-based stats. Identities = 27/147 (18%), Positives = 51/147 (34%), Gaps = 8/147 (5%) Query: 7 ILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALK-ID 65 LY Y + R+ LK I E+ L+ D + T QVP L+ D Sbjct: 2 KLYIYDHCPYCLKARMIFGLKNIPVELHV--LLNDDAETPTRMVGQK----QVPILQKDD 55 Query: 66 GITIVQSLAIMEYLEETRPIPRLLPQ-DPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQ 124 + +S+ I+ Y+++ P L + P +R ++ + P S + Sbjct: 56 SRYMPESMDIVHYVDKLDGKPLLTGKRSPAIEEWLRKVNGYANKLLLPRFAKSAFDEFST 115 Query: 125 ENQMQWAQKVITSGFNALEKILQSTAG 151 ++ + +L + G Sbjct: 116 PAARKYFVDKKEASAGNFADLLAHSDG 142 >6GCB-A nrPDB Length = 325 Score = 54.6 bits (130), Expect = 3e-08, Method: Composition-based stats. Identities = 45/238 (18%), Positives = 82/238 (34%), Gaps = 55/238 (23%) Query: 4 GKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMK------ 57 G+ LY + + R I +KG++ EIV + ++ F ++P Sbjct: 46 GRYHLYVAYSCPWATRTLIVRKIKGLE-EIVGVTIVSPLFSAHGWPFGDVSPFPGAEADP 104 Query: 58 ----------------------QVPAL---KIDGITIVQSLAIM--------EYLEETRP 84 VP L K + + +S I+ E+L + Sbjct: 105 FYNAQYVRDLYLRADPKYEGRFTVPVLWDKKTETVVNNESSEIIRIFNTAFNEFLPADKA 164 Query: 85 IPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQKVITSGFNALEK 144 L P+ ++ + I++ + + + + + A + + LEK Sbjct: 165 AIHLYPEAL--KSEIDEINEWVYDTVN--NGVYKAGFATTQQAYEAAVIPLFESLDRLEK 220 Query: 145 ILQSTAGKYCVGDEVSMADVCLVPQV-----ANAERFKVDLSP----YPTISHINKEL 193 IL Y VGD+++ ADV L + A FK +L YP I ++L Sbjct: 221 ILTGK--DYLVGDQLTEADVRLFVTIIRFDPAYVGHFKCNLRTIRDGYPAIHLWLRKL 276 >4WR5-A nrPDB Length = 244 Score = 53.9 bits (128), Expect = 5e-08, Method: Composition-based stats. Identities = 24/160 (15%), Positives = 54/160 (33%), Gaps = 8/160 (5%) Query: 39 IKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAI 98 +G + ++F+ +P + + QS+AI+ + + +L P++RA Sbjct: 59 RDEGDKWRNKKFELGLEFPNLPYXIDGDVKLTQSMAIIRXIADKH---NMLGGCPKERAE 115 Query: 99 VRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDE 158 + M+ + + ++ K + + E L GD Sbjct: 116 ISMLEGAVLDIRYGVSRIAYSKDFETLKVDFLS--KLPEMLKMFEDRLCHKTX--LNGDH 171 Query: 159 VSMADVCLVPQVANAERFK-VDLSPYPTISHINKELLALE 197 V+ D L + + L +P + K + A+ Sbjct: 172 VTHPDFMLYDALDVVLXMDPMCLDAFPKLVCFKKRIEAIP 211 >4BVY-B nrPDB Length = 186 Score = 53.5 bits (127), Expect = 7e-08, Method: Composition-based stats. Identities = 27/150 (18%), Positives = 51/150 (34%), Gaps = 27/150 (18%) Query: 58 QVPALKI-DGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNL 116 Q+P L+ DG ++ I +L + LL +++AIV+ + + + Sbjct: 41 QIPVLQTNDGPSLTGLTTIAAHLVKQANKEYLLGSTAEEKAIVQQWLEYRVTQV------ 94 Query: 117 SVLKQVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERF 176 ++ I + L L+ Y G ++AD+ L RF Sbjct: 95 ----------DGHSSKNDIHTLLKDLNSYLEDKV--YLTGYNFTLADILLY---YGLHRF 139 Query: 177 KVDLS-----PYPTISHINKELLALEVFQV 201 VDL+ Y +S + + Sbjct: 140 IVDLTVQEKEKYLNVSRWFSHIQHYPGIRQ 169 >2YV7-A nrPDB Length = 260 Score = 52.7 bits (125), Expect = 1e-07, Method: Composition-based stats. Identities = 31/193 (16%), Positives = 68/193 (35%), Gaps = 26/193 (13%) Query: 22 IALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSLAIMEYLEE 81 + LK I ++ +++ K F F+ +P P L +G+ I+++ I ++ + Sbjct: 52 LLAELKTISLKVTTVDMQKPPPD-FRTNFEATHP----PILIDNGLAILENEKIERHIMK 106 Query: 82 TRPIP-RLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQKVITSGFN 140 P L QD + ++ NL V ++ + + + S Sbjct: 107 NIPGGYNLFVQDKEVATLIE--------------NLYVKLKLMLVKKDEAKNNALLSHLR 152 Query: 141 ALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDLSPY------PTISHINKELL 194 + L + ++ GD + D L+P++ + + + + Sbjct: 153 KINDHLSARNTRFLTGDTMCCFDCELMPRLQHIRVAGKYFVDFEIPTHLTALWRYMYHMY 212 Query: 195 ALEVFQVSHPRRQ 207 L+ F S P Q Sbjct: 213 QLDAFTQSCPADQ 225 >6GZF-A nrPDB Length = 341 Score = 51.9 bits (123), Expect = 2e-07, Method: Composition-based stats. Identities = 41/210 (19%), Positives = 76/210 (36%), Gaps = 47/210 (22%) Query: 2 QAGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIK----DGGQQFTEE-------- 49 +AG+ LY + + R + LKG++ + + ++++ + G QFT E Sbjct: 52 EAGRYHLYVSYACPWAHRTLVTRTLKGLE-DAISVSVVDPYRAEDGWQFTPEKEGCTHDH 110 Query: 50 ----------FQTLNP----MKQVPAL---KIDGITIVQSLAIMEYLEETR-----PIPR 87 + P VP L + D I +S IM + Sbjct: 111 VHDVDYLRELYVRAAPDVTCRVTVPVLWDTEEDTIVNNESEEIMRMFDTEFDEFADHTVD 170 Query: 88 LLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQKVITSGFNAL---EK 144 L P+ Q++ V I D I +P+ N E + + + F AL + Sbjct: 171 LYPEGYQEK--VDQIIDNI---YEPINNGVYRAGFATEQEP--YDEAVAELFGALAHWDD 223 Query: 145 ILQSTAGKYCVGDEVSMADVCLVPQVANAE 174 +L +Y GD ++ AD+ + + + Sbjct: 224 VLAD--QRYLAGDRLTEADIAMFTTLVRFD 251 >3M1G-A nrPDB Length = 362 Score = 48.5 bits (114), Expect = 2e-06, Method: Composition-based stats. Identities = 34/209 (16%), Positives = 68/209 (32%), Gaps = 40/209 (19%) Query: 1 MQAGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIK----------DGGQQFTEEF 50 ++AG+ L + + R I L G++ ++ + L D + Sbjct: 57 VEAGRYRLVAARACPWAHRTVITRRLLGLE-NVISLGLTGPTHDVRSWTFDLDPNHLDPV 115 Query: 51 QTL-------------NPMK-QVPALKIDGITI-----VQSLAIMEYLEETR----PIPR 87 + P VPAL + S+ I LE + P Sbjct: 116 LQIPRLQDAYFNRFPDYPRGITVPALVEESSKKVVTNDYPSITIDFNLEWKQFHREGAPN 175 Query: 88 LLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQKVITSGFNALEKILQ 147 L P + ++ + ++ + + G + A K + + LE L Sbjct: 176 LYPAELRE-EMAPVMKRIFTEVNNGVYRTGF---AGSQEAHNEAYKRLWVALDWLEDRL- 230 Query: 148 STAGKYCVGDEVSMADVCLVPQVANAERF 176 + +Y +GD ++ AD+ L P + + Sbjct: 231 -STRRYLMGDHITEADIRLYPTLVRFDAV 258 >4G0L-A nrPDB Length = 328 Score = 47.3 bits (111), Expect = 5e-06, Method: Composition-based stats. Identities = 38/231 (16%), Positives = 72/231 (31%), Gaps = 47/231 (20%) Query: 8 LYSYFRSSCSWRVRIALALKGID-YEIVPI--NLIKDGGQQFTEEF-------------- 50 LY + R I LKG++ + V + L+ + G F + F Sbjct: 57 LYVSLACPWAHRTLIMRKLKGLEPFISVSVVNPLMLENGWTFDDSFPGATGDTLYQNEFL 116 Query: 51 ----QTLNP----MKQVPAL---KIDGITIVQSLAIMEYLEETR-----PIPRLLPQDPQ 94 +P VP L K I +S I+ P P Sbjct: 117 YQLYLHADPHYSGRVTVPVLWDKKNHTIVSNESAEIIRMFNTAFDALGAKAGDYYP--PA 174 Query: 95 KRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQKVITSGFNALEKILQSTAGKYC 154 + + ++ I + + + A + LE+IL +Y Sbjct: 175 LQTKIDELNGWIYDTVN--NGVYKAGFATSQEAYDEAVAKVFESLARLEQILGQH--RYL 230 Query: 155 VGDEVSMADVCLVPQVANAE-----RFKVD---LSPYPTISHINKELLALE 197 G++++ AD+ L + + FK D +S Y + +++ + Sbjct: 231 TGNQLTEADIRLWTTLVRFDPVYVTHFKCDKHRISDYLNLYGFLRDIYQMP 281 >4PTS-A nrPDB Length = 348 Score = 45.8 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 25/124 (20%), Positives = 47/124 (37%), Gaps = 14/124 (11%) Query: 84 PIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQKVITSGFNALE 143 P+L P+ RA + +S I + + + G ++ A + + + L Sbjct: 158 GAPQLYPE--HLRAEIDEVSKGIYTEVN--NGVYRCGFAGSQDAYDAAYDRLFTKLDELS 213 Query: 144 KILQSTAGKYCVGDEVSMADVCLVPQVANAERF--------KVDLSPYPTISHINKELLA 195 + L +Y VGD ++ ADV L +A + + LS P + ++L Sbjct: 214 ERLAQ--QRYLVGDTITEADVRLFTTLARFDAVYHGHFKCNRSKLSEMPVLWAYARDLFQ 271 Query: 196 LEVF 199 F Sbjct: 272 TPGF 275 >4LMV-A nrPDB Length = 252 Score = 43.1 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 33/150 (22%), Positives = 57/150 (38%), Gaps = 14/150 (9%) Query: 14 SSCSWRVRIALALKGIDY--EIVPINLIKDGGQQFTEEFQTLNPMK----QVPALKI-DG 66 S +W++R AL +KGI Y E V I+D ++ + P VP + + Sbjct: 21 SPNTWKIRYALNIKGIKYKTEWVEYPDIEDVVKKLGGKPTGKKPDGRDHYTVPVIYDPNT 80 Query: 67 ITIVQSLA-IMEYLEETRPI-PRLLPQ--DPQKRAIVRMISDLIASGIQPLQNLSVLKQV 122 T+V+ I +YL++ P PRL P D + A + + + L + Sbjct: 81 KTVVEDGIKIAKYLDDAYPDTPRLFPAGTDAFQAAFDDFVWSVTLAFPLLSLLLLDVSNS 140 Query: 123 GQENQMQWAQKVITSGFNALEKILQSTAGK 152 + + F K L+ G+ Sbjct: 141 LPPRSSAYFRATREQQFG---KRLEEQGGE 167 >4USS-A nrPDB Length = 325 Score = 41.9 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 27/158 (17%), Positives = 56/158 (35%), Gaps = 25/158 (15%) Query: 58 QVPALKIDGITIV---QSLAIMEY-------LEETRPIPRLLPQDPQKRAIVRMISDLIA 107 VP L + + +S I+ + E + L P +A + + + Sbjct: 128 TVPVLWDKKLKTIVNNESSEIIRMFNTEFNDIAENAALD-LYPS--HLQAQIDETNGWVY 184 Query: 108 SGIQPLQNLSVLKQVGQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLV 167 GI + ++ + A + + E+IL +Y G+ +S AD+ L Sbjct: 185 DGIN--NGVYKCGFARKQGPYEEAAIQLYEALDKCEEIL--GRQRYICGNTLSEADIKLF 240 Query: 168 PQVANAE-----RFKVD---LSPYPTISHINKELLALE 197 + + FK + L YP + + K++ + Sbjct: 241 VTLIRFDEVYAVHFKCNKKLLRDYPNMFNYTKDIFQIP 278 >5LKB-A nrPDB Length = 378 Score = 41.5 bits (96), Expect = 3e-04, Method: Composition-based stats. Identities = 41/205 (20%), Positives = 72/205 (35%), Gaps = 56/205 (27%) Query: 31 YEIVPI-NLIKDGGQQFTEEFQTLNPMKQVPAL-KIDGITIV--QSLAIM---------E 77 Y I +L Q++ F VP L ++ TIV +S I+ E Sbjct: 136 YGYKRISDLYYKSDPQYSARF-------TVPVLWDLETQTIVNNESSEIIRILNSSAFDE 188 Query: 78 YLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQKVITS 137 ++++ L+P A ++ D S + N V K E + + + + Sbjct: 189 FVDDDHKKTDLVP------AQLKTQIDDFNSWVYDSINNGVYKTGFAEK-AEVYESEVNN 241 Query: 138 GFNALEKILQSTAGKYC--------------------VGDEVSMADVCLVPQV-----AN 172 F L+K+ + + KY VGD+++ AD+ L V Sbjct: 242 VFEHLDKVEKILSDKYSKLKAKYGEEDRQKILGEFFTVGDQLTEADIRLYTTVIRFDPVY 301 Query: 173 AERFKVDLSP----YPTISHINKEL 193 + FK + + YP I + L Sbjct: 302 VQHFKCNFTSIRAGYPFIHLWVRNL 326 >5CAX-A nrPDB Length = 101 Score = 41.2 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 13/79 (16%), Positives = 36/79 (45%), Gaps = 4/79 (5%) Query: 4 GKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALK 63 GK ++Y + + L G+D+E V ++L+++ ++ + + ++ P++ Sbjct: 20 GKIVMYGLSTCVWCKKTKKLLTDLGVDFEYVFVDLLEE--EEKSNAIKQVSRFN--PSVS 75 Query: 64 IDGITIVQSLAIMEYLEET 82 + AI+ + E+ Sbjct: 76 FPTTILNDEKAIVGFKEKQ 94 >2YV9-A nrPDB Length = 291 Score = 39.6 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 24/177 (13%), Positives = 62/177 (35%), Gaps = 17/177 (9%) Query: 23 ALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITIV--QSLAI---ME 77 AL G+ V + + + F + F P P + + + + I + Sbjct: 49 ALYEIGVA--RVEVKTVNVNSEAFKKNFLGAQP----PIMIEEEKELTYTDNREIEGRIF 102 Query: 78 YLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQKVIT- 136 +L + +P L +DP + + ++ K+ + AQ + Sbjct: 103 HLAKEFNVP-LFEKDPSAEKRIENLYRNFKLFLRAKVEFDKGKKEPSRVEDLPAQIKVHY 161 Query: 137 ----SGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDLSPYPTISHI 189 + ++++L +Y +G+ ++ D L+P++ + + L + + Sbjct: 162 NRVCEQLSNIDQLLSERKSRYLLGNSMTEYDCELMPRLHHIRIIGLSLLGFDIPHNF 218 >4LA1-A nrPDB Length = 602 Score = 38.1 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 13/78 (16%), Positives = 35/78 (44%), Gaps = 1/78 (1%) Query: 1 MQAGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVP 60 +++ I++S +++ LA I + + ++ + + G + + ++ VP Sbjct: 21 IESAAVIVFSKTTCPFCKKLKDVLAEAKIKHATIELDQLSN-GSVIQKALSNFSKIETVP 79 Query: 61 ALKIDGITIVQSLAIMEY 78 + + G I S A++ Y Sbjct: 80 QMFVRGKFIGDSKAVLNY 97 >2PBJ-A nrPDB Length = 290 Score = 37.7 bits (86), Expect = 0.004, Method: Composition-based stats. Identities = 20/113 (17%), Positives = 40/113 (35%), Gaps = 15/113 (13%) Query: 5 KPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALK- 63 + LY Y +VR L + Y++V +N + + ++VP L Sbjct: 14 QLTLYQYKTCPFCSKVRAFLDFHALPYQVVEVNPVLRAE-------IKFSSYRKVPILVA 66 Query: 64 ---IDGITIVQSLAIME----YLEETRPIPRLLPQDPQKRAIVRMISDLIASG 109 + S I+ YL +P+ ++ P +A+ ++ G Sbjct: 67 QEGESSQQLNDSSVIISALKTYLVSGQPLEEIITYYPAMKAVNDQGKEVTEFG 119 >2JZR-A nrPDB Length = 144 Score = 36.9 bits (84), Expect = 0.007, Method: Composition-based stats. Identities = 26/116 (22%), Positives = 44/116 (37%), Gaps = 27/116 (23%) Query: 1 MQAGKPILYSYFRSSCSWRVRIALALKGIDYEIVPIN----------------LIKDGGQ 44 ++ KP L ++ S C + L+ G E + L + Sbjct: 21 LKKDKPTLIKFWASWCP----LCLSELG-QTEKWAQDAKFSSANLITVASPGFLHEKKDG 75 Query: 45 QFTEEFQTLNPMKQVPALKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVR 100 F + + LN ++P + +G TI QSL I Y P L+ +D + IV+ Sbjct: 76 DFQKWYAGLNYP-KLPVVTDNGGTIAQSLNISVY-----PSWALIGKDGDVQRIVK 125 >2X8H-A nrPDB Length = 598 Score = 36.5 bits (83), Expect = 0.008, Method: Composition-based stats. Identities = 14/76 (18%), Positives = 34/76 (44%), Gaps = 1/76 (1%) Query: 3 AGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPAL 62 + IL+S +V+ LA I + + ++ + + G + + + ++ VP + Sbjct: 17 SAAVILFSKTTCPYCKKVKDVLAEAKIKHATIELDQLSN-GSAIQKCLASFSKIETVPQM 75 Query: 63 KIDGITIVQSLAIMEY 78 + G I S +++Y Sbjct: 76 FVRGKFIGDSQTVLKY 91 >3GRX-A nrPDB Length = 82 Score = 36.5 bits (83), Expect = 0.009, Method: Composition-based stats. Identities = 19/89 (21%), Positives = 34/89 (38%), Gaps = 11/89 (12%) Query: 8 LYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGI 67 +Y+ S R + L+ KG+ ++ +PI+ G EE + VP + ID Sbjct: 5 IYTKETCPYSHRAKALLSSKGVSFQELPID----GNAAKREEMIKRSGRTTVPQIFIDAQ 60 Query: 68 TIVQSLAIMEYLEETRPIPRLLPQDPQKR 96 I Y ++ + DP + Sbjct: 61 H------IGGY-DDLYALDARGGLDPLLK 82 >3QMX-A nrPDB Length = 99 Score = 35.4 bits (80), Expect = 0.020, Method: Composition-based stats. Identities = 17/91 (18%), Positives = 31/91 (34%), Gaps = 8/91 (8%) Query: 3 AGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQ--VP 60 + K +Y++ R L KG++++ I+ G E + +P Sbjct: 15 SAKIEIYTWSTCPFCMRALALLKRKGVEFQEYCID-----GDNEAREAMAARANGKRSLP 69 Query: 61 ALKIDGITIVQSLAIMEYLEETRPIPRLLPQ 91 + ID I I L+ + LL Sbjct: 70 QIFIDDQHIGGCDDIYA-LDGAGKLDPLLHS 99 >2H30-A nrPDB Length = 164 Score = 35.4 bits (80), Expect = 0.021, Method: Composition-based stats. Identities = 25/116 (21%), Positives = 45/116 (38%), Gaps = 27/116 (23%) Query: 1 MQAGKPILYSYFRSSCSWRVRIALALKGIDYEIVPIN----------------LIKDGGQ 44 ++ KP L ++ S C + L+ G E + L + Sbjct: 35 LKKDKPTLIKFWASWCP----LCLSELG-QAEKWAQDAKFSSANLITVASPGFLHEKKDG 89 Query: 45 QFTEEFQTLNPMKQVPALKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVR 100 +F + + LN ++P + +G TI Q+L I Y P L+ +D + IV+ Sbjct: 90 EFQKWYAGLNYP-KLPVVTDNGGTIAQNLNISVY-----PSWALIGKDGDVQRIVK 139 >3IC4-A nrPDB Length = 92 Score = 35.0 bits (79), Expect = 0.024, Method: Composition-based stats. Identities = 14/83 (16%), Positives = 33/83 (39%), Gaps = 7/83 (8%) Query: 4 GKPILYSYFRSSCSWRVRIALALKGIDYEIVPIN-LIKDGGQQFTEEFQTLNPMKQVPAL 62 + ++Y R L +G+D+E++ I+ L + ++ E+ +++ VP + Sbjct: 12 AEVLMYGLSTCPHCKRTLEFLKREGVDFEVIWIDKLEGEERKKVIEKVHSISGSYSVPVV 71 Query: 63 KIDGITIVQSLAIMEYLEETRPI 85 + + Y EE Sbjct: 72 VKGDKHV------LGYNEEKLKE 88 >3NZN-A nrPDB Length = 103 Score = 35.0 bits (79), Expect = 0.027, Method: Composition-based stats. Identities = 18/79 (22%), Positives = 33/79 (41%), Gaps = 6/79 (7%) Query: 4 GKPILYSYFRSSCSWRVRIALALKGIDYEIVPIN-LIKDGGQQFTEEFQTLNPMKQVPAL 62 GK I+Y + + L G+D++ V ++ L ++ EE + NP P Sbjct: 22 GKVIMYGLSTCVWCKKTKKLLTDLGVDFDYVYVDRLEGKEEEEAVEEVRRFNPSVSFPTT 81 Query: 63 KIDGITIVQSLAIMEYLEE 81 I+ AI+ + E+ Sbjct: 82 IINDEK-----AIVGFKEK 95 >2MYG-A nrPDB Length = 97 Score = 34.6 bits (78), Expect = 0.031, Method: Composition-based stats. Identities = 18/89 (20%), Positives = 38/89 (42%), Gaps = 2/89 (2%) Query: 1 MQAGKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVP 60 ++ K +++S+ R L + D + ++ + + G+Q E + VP Sbjct: 10 IKGNKVVVFSWVTCPYCVRAEKLLHARTKDITVHYVDKMSE-GEQLRGEIYQAYKHETVP 68 Query: 61 ALKIDGITIVQSLAIMEYLEETRPIPRLL 89 A+ I+G I +E L++ + LL Sbjct: 69 AIFINGNFIGGCSD-LEALDKEGKLDGLL 96 >5MB9-A nrPDB Length = 590 Score = 32.3 bits (72), Expect = 0.17, Method: Composition-based stats. Identities = 12/31 (38%), Positives = 15/31 (48%) Query: 30 DYEIVPINLIKDGGQQFTEEFQTLNPMKQVP 60 DYE I L K F++EF NP + P Sbjct: 249 DYEYHGIALDKVLIDHFSKEFLKKNPGAKDP 279 >2MZC-A nrPDB Length = 92 Score = 31.1 bits (69), Expect = 0.39, Method: Composition-based stats. Identities = 16/85 (18%), Positives = 30/85 (35%), Gaps = 5/85 (5%) Query: 5 KPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKI 64 I+Y+ R + LA KG ++ + + E Q + P + I Sbjct: 7 DVIIYTRPGCPYCARAKALLARKGAEFNEID----ASATPELRAEMQERSGRNTFPQIFI 62 Query: 65 DGITIVQSLAIMEYLEETRPIPRLL 89 + + S + LE+ + LL Sbjct: 63 GSVHVGGSDDLYA-LEDEGKLDSLL 86 >2KLX-A nrPDB Length = 89 Score = 30.8 bits (68), Expect = 0.46, Method: Composition-based stats. Identities = 18/85 (21%), Positives = 26/85 (30%), Gaps = 6/85 (7%) Query: 5 KPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKI 64 + ILY+ R R L KG+ Y + E Q N P + I Sbjct: 7 EIILYTRPNCPYCKRARDLLDKKGVKYTDI-----DASTSLRQEMVQRANGRNTFPQIFI 61 Query: 65 DGITIVQSLAIMEYLEETRPIPRLL 89 + + LE + LL Sbjct: 62 GDYHVGGCDDLYA-LENKGKLDSLL 85 >1NM3-A nrPDB Length = 241 Score = 30.8 bits (68), Expect = 0.52, Method: Composition-based stats. Identities = 12/73 (16%), Positives = 27/73 (36%), Gaps = 5/73 (6%) Query: 8 LYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGI 67 +++ + + L KG+ +E + + G + ++ VP + I G Sbjct: 174 IFTKPGCPFCAKAKQLLHDKGLSFEEIIL-----GHDATIVSVRAVSGRTTVPQVFIGGK 228 Query: 68 TIVQSLAIMEYLE 80 I S + +Y Sbjct: 229 HIGGSDDLEKYFA 241 >3D3U-A nrPDB Length = 439 Score = 30.0 bits (66), Expect = 0.71, Method: Composition-based stats. Identities = 12/67 (17%), Positives = 27/67 (40%), Gaps = 3/67 (4%) Query: 59 VPALKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSV 118 VP LK +G + ++Y+ + RL ++RA ++ + +P + Sbjct: 370 VPILK-EGACVTTGRNEVDYVVTEYGVARLRGATLRQRAEA--LTAIAHPDFRPALEEEI 426 Query: 119 LKQVGQE 125 ++ E Sbjct: 427 RRRFELE 433 >2IUJ-A nrPDB Length = 853 Score = 29.6 bits (65), Expect = 0.93, Method: Composition-based stats. Identities = 16/91 (17%), Positives = 36/91 (39%), Gaps = 5/91 (5%) Query: 65 DGITIVQSLA--IMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQV 122 DG+ I ++ + EY+ L +DP+ +A +L+ G L++ +++ Sbjct: 627 DGLEIWDAIKSWVEEYVSFYYKSDEELQKDPELQAW---WKELVEVGHGDLKDKPWWQKM 683 Query: 123 GQENQMQWAQKVITSGFNALEKILQSTAGKY 153 ++ A + +AL + Y Sbjct: 684 QTREELVEASATLIWIASALHAAVNFGQYPY 714 >3RHC-A nrPDB Length = 113 Score = 29.2 bits (64), Expect = 1.5, Method: Composition-based stats. Identities = 13/66 (19%), Positives = 25/66 (37%) Query: 4 GKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALK 63 ++YS S V+ G+ +V ++ + G Q + + L VP + Sbjct: 19 NTVVIYSKTWCSYCTEVKTLFKRLGVQPLVVELDQLGPQGPQLQKVLERLTGQHTVPNVF 78 Query: 64 IDGITI 69 + G I Sbjct: 79 VCGKHI 84 >1THX-A nrPDB Length = 115 Score = 28.8 bits (63), Expect = 1.7, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 30/77 (38%), Gaps = 9/77 (11%) Query: 1 MQAGKPILYSYFRSSCS----WRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPM 56 ++A +P+L ++ S C I LA + + L D + Sbjct: 22 LKAEQPVLVYFWASWCGPCQLMSPLINLAANTYSDRLKVVKLEIDP----NPTTVKKYKV 77 Query: 57 KQVPALK-IDGITIVQS 72 + VPAL+ + G I+ S Sbjct: 78 EGVPALRLVKGEQILDS 94 >3ZZN-A nrPDB Length = 310 Score = 28.8 bits (63), Expect = 1.7, Method: Composition-based stats. Identities = 11/34 (32%), Positives = 17/34 (50%) Query: 23 ALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPM 56 ALAL G+ E+V ++L + Q E+ P Sbjct: 18 ALALLGVAREVVLVDLDRKLAQAHAEDILHATPF 51 >4K38-A nrPDB Length = 370 Score = 28.4 bits (62), Expect = 2.6, Method: Composition-based stats. Identities = 9/66 (13%), Positives = 22/66 (33%) Query: 96 RAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQKVITSGFNALEKILQSTAGKYCV 155 R + ++ + LQ ++ L + +E L+ + + Sbjct: 172 RHVNKVYKYFKEKDFKFLQFINCLDPLYEEKGKYNYSLKPKDYTKFLKNLFDFWYEDFLN 231 Query: 156 GDEVSM 161 G+ VS+ Sbjct: 232 GNRVSI 237 >1YMG-A nrPDB Length = 263 Score = 28.4 bits (62), Expect = 2.6, Method: Composition-based stats. Identities = 11/42 (26%), Positives = 19/42 (45%), Gaps = 3/42 (7%) Query: 178 VDLSPYPTISHINKELLALEVFQVSHPRRQP---DTPAELRT 216 D +P + +++ L L+ + S QP P EL+T Sbjct: 219 YDFLLFPRLKSVSERLSILKGSRPSESNGQPEVTGEPVELKT 260 >4R0M-B nrPDB Length = 643 Score = 27.7 bits (60), Expect = 4.6, Method: Composition-based stats. Identities = 23/110 (20%), Positives = 43/110 (39%), Gaps = 19/110 (17%) Query: 69 IVQSLA--IMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQEN 126 + S I +YL + R + LPQ +R I + S+++ L++ + + G Sbjct: 547 LFSSRIQEIDQYLAKERQKNQTLPQSENERQIAAVWSEVLQLTSVGLED-NFFELGGHSI 605 Query: 127 QMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERF 176 + Q + FN ++S+A++ P VA RF Sbjct: 606 HLIRVQNELEKLFNR----------------QLSLAEMFKNPTVATLARF 639 >1HX8-A nrPDB Length = 299 Score = 27.3 bits (59), Expect = 5.5, Method: Composition-based stats. Identities = 27/180 (15%), Positives = 52/180 (28%), Gaps = 31/180 (17%) Query: 10 SYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNP---MKQVPALKIDG 66 Y S R L K + Y + + K + +++N +K +P L+ Sbjct: 130 GYDMSPFIRRYAKYLNEKSLSYRAMAFDFCKVKRGKEEGSLRSMNAEKLLKTLPVLQAQL 189 Query: 67 ITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQEN 126 +++ L + + R + L A + NL E Sbjct: 190 DALLEFDCQSNDLSNGVINMSFM-------LLFRDLIRLFACYNDGIINLL-------EK 235 Query: 127 QMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKVDLSPYPTI 186 +K + +K L VG+ + +A E +D P + Sbjct: 236 YFDMNKKHARDALDLYKKFLVRMDR---VGEFLKVA-----------ENVGIDKGDIPDL 281 >4QKU-A nrPDB Length = 441 Score = 27.3 bits (59), Expect = 5.9, Method: Composition-based stats. Identities = 14/31 (45%), Positives = 17/31 (54%) Query: 185 TISHINKELLALEVFQVSHPRRQPDTPAELR 215 TIS L ALE F+V+ P + P A LR Sbjct: 281 TISPWIVTLDALEPFRVAQPEQSPQPLAYLR 311 >3WDK-A nrPDB Length = 261 Score = 26.9 bits (58), Expect = 7.0, Method: Composition-based stats. Identities = 21/137 (15%), Positives = 52/137 (37%), Gaps = 13/137 (9%) Query: 49 EFQTLNPMKQVPALKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKR--AIVRMISDLI 106 E +NP K++P L+ + + ++ + L+P + R A+VRM ++ Sbjct: 126 EILGINPTKRIPGLEHERGKVDENGI-------WKADVVLVPLEDGDRTEALVRMGKFVV 178 Query: 107 ASGIQPLQNLSVLKQVGQENQMQWAQ----KVITSGFNALEKILQSTAGKYCVGDEVSMA 162 + PL + + + + + A ++ + + L G+Y G +S Sbjct: 179 TVDLNPLSRSARMADITIVDNIVRAYPRMVELAREMKDYSREELLKIVGEYDNGKTLSDV 238 Query: 163 DVCLVPQVANAERFKVD 179 + + ++ + Sbjct: 239 LLHIRDRLTRLAEEGIW 255 >5TI1-A nrPDB Length = 444 Score = 26.5 bits (57), Expect = 8.9, Method: Composition-based stats. Identities = 14/31 (45%), Positives = 17/31 (54%) Query: 185 TISHINKELLALEVFQVSHPRRQPDTPAELR 215 TIS L ALE F+V+ P + P A LR Sbjct: 285 TISPWIVTLDALEPFRVAQPAQDPQPLAYLR 315 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.138 0.363 Lambda K H 0.267 0.0418 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 7,865,995 Number of Sequences: 36641 Number of extensions: 281038 Number of successful extensions: 1574 Number of sequences better than 10.0: 172 Number of HSP's better than 10.0 without gapping: 229 Number of HSP's successfully gapped in prelim test: 42 Number of HSP's that attempted gapping in prelim test: 917 Number of HSP's gapped (non-prelim): 281 length of query: 216 length of database: 10,336,785 effective HSP length: 93 effective length of query: 123 effective length of database: 6,929,172 effective search space: 852288156 effective search space used: 852288156 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 57 (26.5 bits)