BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9WUD2 (761 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5HI9-A nrPDB 1570 0.0 6BO5-A nrPDB 1349 0.0 6OO7-A nrPDB 1156 0.0 5AN8-A nrPDB 976 0.0 5IRX-A nrPDB 656 0.0 6BBJ-A nrPDB 579 e-165 6C8G-A nrPDB 572 e-163 2ETB-A nrPDB 514 e-146 2F37-A nrPDB 452 e-127 6DVZ-A nrPDB 444 e-125 6MHW-A nrPDB 435 e-122 2NYJ-A nrPDB 261 1e-69 4DX2-A nrPDB 257 1e-68 3W9G-A nrPDB 257 2e-68 6BOA-A nrPDB 234 1e-61 6DMR-A nrPDB 228 6e-60 6E2G-A nrPDB 226 2e-59 4N5Q-A nrPDB 168 1e-41 2RFA-A nrPDB 111 1e-24 6G1K-A nrPDB 50 5e-06 5AQ7-A nrPDB 42 8e-04 5Z96-A nrPDB 41 0.002 6FES-A nrPDB 40 0.004 6AUN-A nrPDB 40 0.004 5H76-A nrPDB 40 0.005 5AQ9-A nrPDB 39 0.007 6BPQ-A nrPDB 39 0.009 4OT9-A nrPDB 39 0.010 5AQA-A nrPDB 38 0.015 5AQB-A nrPDB 37 0.023 5MIO-C nrPDB 37 0.034 6MWQ-A nrPDB 36 0.053 5GP7-A nrPDB 36 0.079 5HKP-A nrPDB 34 0.22 6CUD-A nrPDB 34 0.23 5JHQ-A nrPDB 34 0.24 4O1O-A nrPDB 34 0.25 6CV9-A nrPDB 33 0.37 5CBO-A nrPDB 32 0.77 1WG0-A nrPDB 31 2.4 5Z1F-A nrPDB 31 2.6 1BD8-A nrPDB 30 5.2 6BWI-A nrPDB 30 5.2 6EMK-G nrPDB 29 5.9 5ET1-A nrPDB 29 7.5 >5HI9-A nrPDB Length = 770 Score = 1570 bits (4064), Expect = 0.0, Method: Compositional matrix adjust. Identities = 760/761 (99%), Positives = 760/761 (99%) Query: 1 MTSASSPPAFRLETSDGDEEGNAEVNKGKQEPPPMESPFQREDRNSSPQIKVNLNFIKRP 60 MTSASSPPAFRLETSDGDEEGNAEVNKGKQEPPPMESPFQREDRNSSPQIKVNLNFIKRP Sbjct: 1 MTSASSPPAFRLETSDGDEEGNAEVNKGKQEPPPMESPFQREDRNSSPQIKVNLNFIKRP 60 Query: 61 PKNTSAPSQQEPDRFDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTC 120 PKNTSAPSQQEPDRFDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTC Sbjct: 61 PKNTSAPSQQEPDRFDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTC 120 Query: 121 LMKAVLNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCV 180 LMKAVLNLQDGVNACIMPLLQIDKDSGNPK LVNAQCTDEFYQGHSALHIAIEKRSLQCV Sbjct: 121 LMKAVLNLQDGVNACIMPLLQIDKDSGNPKPLVNAQCTDEFYQGHSALHIAIEKRSLQCV 180 Query: 181 KLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLE 240 KLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLE Sbjct: 181 KLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLE 240 Query: 241 ATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLK 300 ATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLK Sbjct: 241 ATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLK 300 Query: 301 LAAKEGKIEIFRHILQREFSGPYQPLSRKFTEWCYGPVRVSLYDLSSVDSWEKNSVLEII 360 LAAKEGKIEIFRHILQREFSGPYQPLSRKFTEWCYGPVRVSLYDLSSVDSWEKNSVLEII Sbjct: 301 LAAKEGKIEIFRHILQREFSGPYQPLSRKFTEWCYGPVRVSLYDLSSVDSWEKNSVLEII 360 Query: 361 AFHCKSPNRHRMVVLEPLNKLLQEKWDRLVSRFFFNFACYLVYMFIFTVVAYHQPSLDQP 420 AFHCKSPNRHRMVVLEPLNKLLQEKWDRLVSRFFFNFACYLVYMFIFTVVAYHQPSLDQP Sbjct: 361 AFHCKSPNRHRMVVLEPLNKLLQEKWDRLVSRFFFNFACYLVYMFIFTVVAYHQPSLDQP 420 Query: 421 AIPSSKATFGESMLLLGHILILLGGIYLLLGQLWYFWRRRLFIWISFMDSYFEILFLLQA 480 AIPSSKATFGESMLLLGHILILLGGIYLLLGQLWYFWRRRLFIWISFMDSYFEILFLLQA Sbjct: 421 AIPSSKATFGESMLLLGHILILLGGIYLLLGQLWYFWRRRLFIWISFMDSYFEILFLLQA 480 Query: 481 LLTVLSQVLRFMETEWYLPLLVLSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRF 540 LLTVLSQVLRFMETEWYLPLLVLSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRF Sbjct: 481 LLTVLSQVLRFMETEWYLPLLVLSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRF 540 Query: 541 LLVYLVFLFGFAVALVSLSREARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDASLEL 600 LLVYLVFLFGFAVALVSLSREARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDASLEL Sbjct: 541 LLVYLVFLFGFAVALVSLSREARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDASLEL 600 Query: 601 FKFTIGMGELAFQEQLRFRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNHVADNSWSIW 660 FKFTIGMGELAFQEQLRFRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNHVADNSWSIW Sbjct: 601 FKFTIGMGELAFQEQLRFRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNHVADNSWSIW 660 Query: 661 KLQKAISVLEMENGYWWCRRKKHREGRLLKVGTRGDGTPDERWCFRVEEVNWAAWEKTLP 720 KLQKAISVLEMENGYWWCRRKKHREGRLLKVGTRGDGTPDERWCFRVEEVNWAAWEKTLP Sbjct: 661 KLQKAISVLEMENGYWWCRRKKHREGRLLKVGTRGDGTPDERWCFRVEEVNWAAWEKTLP 720 Query: 721 TLSEDPSGPGITGNKKNPTSKPGKNSASEEDHLPLQVLQSP 761 TLSEDPSGPGITGNKKNPTSKPGKNSASEEDHLPLQVLQSP Sbjct: 721 TLSEDPSGPGITGNKKNPTSKPGKNSASEEDHLPLQVLQSP 761 >6BO5-A nrPDB Length = 695 Score = 1349 bits (3491), Expect = 0.0, Method: Compositional matrix adjust. Identities = 654/656 (99%), Positives = 655/656 (99%) Query: 72 PDRFDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDG 131 PDRFDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDG Sbjct: 32 PDRFDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDG 91 Query: 132 VNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVH 191 VNACIMPLLQIDKDSGNPK LVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVH Sbjct: 92 VNACIMPLLQIDKDSGNPKPLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVH 151 Query: 192 LRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLH 251 LRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLH Sbjct: 152 LRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLH 211 Query: 252 ALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIF 311 ALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIF Sbjct: 212 ALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIF 271 Query: 312 RHILQREFSGPYQPLSRKFTEWCYGPVRVSLYDLSSVDSWEKNSVLEIIAFHCKSPNRHR 371 RHILQREFSGPYQPLSRKFTEWCYGPVRVSLYDLSSVDSWEKNSVLEIIAFHCKSPNRHR Sbjct: 272 RHILQREFSGPYQPLSRKFTEWCYGPVRVSLYDLSSVDSWEKNSVLEIIAFHCKSPNRHR 331 Query: 372 MVVLEPLNKLLQEKWDRLVSRFFFNFACYLVYMFIFTVVAYHQPSLDQPAIPSSKATFGE 431 MVVLEPLNKLLQEKWDRLVSRFFFNFACYLVYMFIFTVVAYHQPSLDQPAIPSSKATFGE Sbjct: 332 MVVLEPLNKLLQEKWDRLVSRFFFNFACYLVYMFIFTVVAYHQPSLDQPAIPSSKATFGE 391 Query: 432 SMLLLGHILILLGGIYLLLGQLWYFWRRRLFIWISFMDSYFEILFLLQALLTVLSQVLRF 491 SMLLLGHILILLGGIYLLLGQLWYFWRRRLFIWISFMDSYFEILFLLQALLTVLSQVLRF Sbjct: 392 SMLLLGHILILLGGIYLLLGQLWYFWRRRLFIWISFMDSYFEILFLLQALLTVLSQVLRF 451 Query: 492 METEWYLPLLVLSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGF 551 METEWYLPLLVLSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGF Sbjct: 452 METEWYLPLLVLSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGF 511 Query: 552 AVALVSLSREARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDASLELFKFTIGMGELA 611 AVALVSLSREARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDASLELFKFTIGMGELA Sbjct: 512 AVALVSLSREARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDASLELFKFTIGMGELA 571 Query: 612 FQEQLRFRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNHVADNSWSIWKLQKAISVLEM 671 FQEQLRFRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNHVADNSWSIWKLQKAISVLEM Sbjct: 572 FQEQLRFRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNHVADNSWSIWKLQKAISVLEM 631 Query: 672 ENGYWWCRRKKHREGRLLKVGTRGDGTPDERWCFRVEEVNWAAWEKTLPTLSEDPS 727 ENGYWWCRRKKHREGRLLKVGTRGDGTPDERWCFRVEEVNWAAWEKTLPTLSEDP+ Sbjct: 632 ENGYWWCRRKKHREGRLLKVGTRGDGTPDERWCFRVEEVNWAAWEKTLPTLSEDPT 687 >6OO7-A nrPDB Length = 786 Score = 1156 bits (2991), Expect = 0.0, Method: Compositional matrix adjust. Identities = 615/767 (80%), Positives = 667/767 (86%), Gaps = 13/767 (1%) Query: 1 MTSASSPPAFRLETSDGDEEGNAEVNKGK----QEPPPMESPFQREDRNSSPQIKVNLNF 56 MTS SSPPAFRLETSDG ++G AEV+K + PPPMES FQ EDRN PQIKVNLN+ Sbjct: 1 MTSPSSPPAFRLETSDGGQDG-AEVDKAQLGYGAGPPPMESRFQDEDRNFPPQIKVNLNY 59 Query: 57 IKRPPKNTSAPSQQEPDRFDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGST 116 + + SQ + +RFDRDRLF+VV+RG PE+L GLLEYLR SKYLTDS YTEGST Sbjct: 60 -----RKGAGASQPDLNRFDRDRLFNVVARGNPEDLAGLLEYLRRTSKYLTDSEYTEGST 114 Query: 117 GKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRS 176 GKTCLMKAVLNLQDGVNACI PLL+ID+DSGNP+ LVNAQCTDE+Y+GHSALHIAIEKRS Sbjct: 115 GKTCLMKAVLNLQDGVNACIQPLLEIDRDSGNPQPLVNAQCTDEYYRGHSALHIAIEKRS 174 Query: 177 LQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQP 236 LQCVKLLVENGA+VH +ACG FFQK+Q TCFYFGELPLSLAACTKQWDVV YLLENPHQP Sbjct: 175 LQCVKLLVENGANVHAKACGHFFQKNQDTCFYFGELPLSLAACTKQWDVVNYLLENPHQP 234 Query: 237 ASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGL 296 ASL+A DSLGNTVLHALVMIAD+S ENSALV+ MYDGLLQ GARLCP VQLE I N +GL Sbjct: 235 ASLQAQDSLGNTVLHALVMIADDSAENSALVVRMYDGLLQAGARLCPNVQLEGIPNLEGL 294 Query: 297 TPLKLAAKEGKIEIFRHILQREFSGPYQPLSRKFTEWCYGPVRVSLYDLSSVDSWEKNSV 356 TPLKLAAKEGKIEIF+HILQREFS P Q LSRKFTEWCYGPVRVSLYDL+SVDSWE+NSV Sbjct: 295 TPLKLAAKEGKIEIFKHILQREFSAPCQSLSRKFTEWCYGPVRVSLYDLASVDSWEENSV 354 Query: 357 LEIIAFHCKSPNRHRMVVLEPLNKLLQEKWDRLVSRFFFNFACYLVYMFIFTVVAYHQPS 416 LEIIAFH +SP+RHRMVVLEPLNKLLQ KWDRL+ RF FNF CYLVYM IFT VAYHQP+ Sbjct: 355 LEIIAFHSRSPHRHRMVVLEPLNKLLQAKWDRLIPRFCFNFLCYLVYMLIFTAVAYHQPA 414 Query: 417 LDQPAIPSSKATFGESMLLLGHILILLGGIYLLLGQLWYFWRRRLFIWISFMDSYFEILF 476 L++ P KAT G SMLLLGHILILLGG+YLLLGQLWYFWRRRLFIWISFMDSY EILF Sbjct: 415 LEKQGFPPLKATAGNSMLLLGHILILLGGVYLLLGQLWYFWRRRLFIWISFMDSYSEILF 474 Query: 477 LLQALLTVLSQVLRFMETEWYLPLLVLSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRD 536 LLQALLTVLSQVL F+ EWYLPLLV SL +GW NLLYYTRGFQHTGIYSVMI+KVILRD Sbjct: 475 LLQALLTVLSQVLCFLAIEWYLPLLVSSLAMGWTNLLYYTRGFQHTGIYSVMIEKVILRD 534 Query: 537 LLRFLLVYLVFLFGFAVALVSLSREARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDA 596 LLRFLLVYLVFLFGFAVALVSLSREA++ + P N+T QP GQE+E PYRSILDA Sbjct: 535 LLRFLLVYLVFLFGFAVALVSLSREAQNSRTPAGPNATEVGQPGAGQEDEAPPYRSILDA 594 Query: 597 SLELFKFTIGMGELAFQEQLRFRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNHVADNS 656 SLELFKFTIGMGELAFQEQLRFRGVVLLLLLAYVLLTYVLLLNMLIALMSETVN VA +S Sbjct: 595 SLELFKFTIGMGELAFQEQLRFRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNSVATDS 654 Query: 657 WSIWKLQKAISVLEMENGYWWCRRKKHREGRLLKVGTRGDGTPDERWCFRVEEVNWAAWE 716 WSIWKLQKAISVLEMENGYWWCRRKK R G +L VGTR DG+PDERWCFRV E+NWA WE Sbjct: 655 WSIWKLQKAISVLEMENGYWWCRRKKQRAGVMLTVGTRPDGSPDERWCFRVGEMNWATWE 714 Query: 717 KTLP-TLSEDPSGPGITGNKKNPT--SKPGKNSASEEDHLPLQVLQS 760 +TLP TL E+PSG G KNPT S+ G++SASEEDHLPLQ+LQS Sbjct: 715 QTLPRTLCEEPSGAAAPGVMKNPTPASQRGEDSASEEDHLPLQLLQS 761 >5AN8-A nrPDB Length = 613 Score = 976 bits (2524), Expect = 0.0, Method: Compositional matrix adjust. Identities = 532/633 (84%), Positives = 562/633 (88%), Gaps = 20/633 (3%) Query: 78 DRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIM 137 DRLF+VV+RG PE+L GLLEYLR SKYLTDS YTEGSTGKTCLMKAVLNLQDGVNACI Sbjct: 1 DRLFNVVARGNPEDLAGLLEYLRRTSKYLTDSEYTEGSTGKTCLMKAVLNLQDGVNACIQ 60 Query: 138 PLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGR 197 PLL+ID+DSGNP+ LVNAQCTDE+Y+GHSALHIAIEKRSLQCVKLLVENGA+VH +ACG Sbjct: 61 PLLEIDRDSGNPQPLVNAQCTDEYYRGHSALHIAIEKRSLQCVKLLVENGANVHAKACGH 120 Query: 198 FFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIA 257 FFQK+Q TCFYFGELPLSLAACTKQWDVV YLLENPH ASL+A DSLGNTVLHALVMIA Sbjct: 121 FFQKNQDTCFYFGELPLSLAACTKQWDVVNYLLENPHPAASLQAQDSLGNTVLHALVMIA 180 Query: 258 DNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQR 317 DNSPENSALV+ MYDGLLQ GARLCP VQLE I N +GLTPLKLAAKEGKIEIF+HILQR Sbjct: 181 DNSPENSALVVRMYDGLLQAGARLCPNVQLEGIPNLEGLTPLKLAAKEGKIEIFKHILQR 240 Query: 318 EFSGPYQPLSRKFTEWCYGPVRVSLYDLSSVDSWEKNSVLEIIAFHCKSPNRHRMVVLEP 377 EFS P Q LSRKFTEWCYGPVRVSLYDL+SVDSWE+NSVLEIIAFH +SP+RHRMVVLEP Sbjct: 241 EFSAPCQSLSRKFTEWCYGPVRVSLYDLASVDSWEENSVLEIIAFHSRSPHRHRMVVLEP 300 Query: 378 LNKLLQEKWDRLVSRFFFNFACYLVYMFIFTVVAYHQPSLDQPAIPSSKATFGESMLLLG 437 LNKLLQ KWDRL+ RF FNF CYLVYM IFT VAYHQP+L++ P KAT G SMLLLG Sbjct: 301 LNKLLQAKWDRLIPRFCFNFLCYLVYMLIFTAVAYHQPALEKQGFPPLKATAGNSMLLLG 360 Query: 438 HILILLGGIYLLLGQLWYFWRRRLFIWISFMDSYFEILFLLQALLTVLSQVLRFMETEWY 497 HILILLGG+YLLLGQLWYFWRRRLFIWISFMDSYFEILFLLQALLTVLSQVL F+ EWY Sbjct: 361 HILILLGGVYLLLGQLWYFWRRRLFIWISFMDSYFEILFLLQALLTVLSQVLCFLAIEWY 420 Query: 498 LPLLVLSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVS 557 LPLLV SLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVS Sbjct: 421 LPLLVSSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVS 480 Query: 558 LSREARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDASLELFKFTIGMGELAFQEQLR 617 LSREA QE+E PYRSILDASLELFKFTIGMGELAFQEQLR Sbjct: 481 LSREA--------------------QEDEAPPYRSILDASLELFKFTIGMGELAFQEQLR 520 Query: 618 FRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNHVADNSWSIWKLQKAISVLEMENGYWW 677 FRGVVLLLLLAYVLLTYVLLLNMLIALMSETVN VA +SWSIWKLQKAISVLEMENGYWW Sbjct: 521 FRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNSVATDSWSIWKLQKAISVLEMENGYWW 580 Query: 678 CRRKKHREGRLLKVGTRGDGTPDERWCFRVEEV 710 CRRKK R G +L VGTR DG+PDERWCFRV E+ Sbjct: 581 CRRKKQRAGVMLTVGTRPDGSPDERWCFRVGEM 613 >5IRX-A nrPDB Length = 636 Score = 656 bits (1692), Expect = 0.0, Method: Compositional matrix adjust. Identities = 338/656 (51%), Positives = 443/656 (67%), Gaps = 31/656 (4%) Query: 75 FDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNA 134 +DR +F V++ +EL LL +L+ + K LTDS + + TGKTCL+KA+LNL +G N Sbjct: 7 YDRRSIFDAVAQSNCQELESLLPFLQRSKKRLTDSEFKDPETGKTCLLKAMLNLHNGQND 66 Query: 135 CIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRA 194 I LL + + + + K VNA TD +Y+G +ALHIAIE+R++ V LLVENGADV A Sbjct: 67 TIALLLDVARKTDSLKQFVNASYTDSYYKGQTALHIAIERRNMTLVTLLVENGADVQAAA 126 Query: 195 CGRFFQKHQGT-CFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHAL 253 G FF+K +G FYFGELPLSLAACT Q +V +LL+N QPA + A DS+GNTVLHAL Sbjct: 127 NGDFFKKTKGRPGFYFGELPLSLAACTNQLAIVKFLLQNSWQPADISARDSVGNTVLHAL 186 Query: 254 VMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRH 313 V +ADN+ +N+ V MY+ +L +GA+L PT++LEEI+N +GLTPL LAA GKI + + Sbjct: 187 VEVADNTVDNTKFVTSMYNEILILGAKLHPTLKLEEITNRKGLTPLALAASSGKIGVLAY 246 Query: 314 ILQREFSGP-YQPLSRKFTEWCYGPVRVSLYDLSSVDSWEKNSVLEIIAFHC-KSPNRHR 371 ILQRE P + LSRKFTEW YGPV SLYDLS +D+ EKNSVLE+IA+ ++PNRH Sbjct: 247 ILQREIHEPECRHLSRKFTEWAYGPVHSSLYDLSCIDTCEKNSVLEVIAYSSSETPNRHD 306 Query: 372 MVVLEPLNKLLQEKWDRLVSR-FFFNFACYLVYMFIFTVVAYHQPSLDQPAIPSSKATFG 430 M+++EPLN+LLQ+KWDR V R F+FNF Y +YM IFT AY++P P K T G Sbjct: 307 MLLVEPLNRLLQDKWDRFVKRIFYFNFFVYCLYMIIFTAAAYYRPVEGLPPYKL-KNTVG 365 Query: 431 ESMLLLGHILILLGGIYLLLGQLWYFWRRRLFIWISFMDSYFEILFLLQALLTVLSQVLR 490 + + G IL + GG+Y + YF +RR + F+DSY EILF +Q+L ++S VL Sbjct: 366 DYFRVTGEILSVSGGVYFFFRGIQYFLQRRPSLKSLFVDSYSEILFFVQSLFMLVSVVLY 425 Query: 491 FMETEWYLPLLVLSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFG 550 F + + Y+ +V SL +GW N+LYYTRGFQ GIY+VMI+K+ILRDL RF+ VYLVFLFG Sbjct: 426 FSQRKEYVASMVFSLAMGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYLVFLFG 485 Query: 551 FAVALVSLSREARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDASLELFKFTIGMGEL 610 F+ A+V+L E Y S+ LELFKFTIGMG+L Sbjct: 486 FSTAVVTLI--------------------------EDGKYNSLYSTCLELFKFTIGMGDL 519 Query: 611 AFQEQLRFRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNHVADNSWSIWKLQKAISVLE 670 F E F+ V ++LLLAYV+LTY+LLLNMLIALM ETVN +A S +IWKLQ+AI++L+ Sbjct: 520 EFTENYDFKAVFIILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAITILD 579 Query: 671 MENGYWWCRRKKHREGRLLKVGTRGDGTPDERWCFRVEEVNWAAWEKTLPTLSEDP 726 E + C RK R G+LL+VG DG D RWCFRV+EVNW W + ++EDP Sbjct: 580 TEKSFLKCMRKAFRSGKLLQVGFTPDGKDDYRWCFRVDEVNWTTWNTNVGIINEDP 635 >6BBJ-A nrPDB Length = 868 Score = 579 bits (1492), Expect = e-165, Method: Compositional matrix adjust. Identities = 317/706 (44%), Positives = 443/706 (62%), Gaps = 21/706 (2%) Query: 34 PMESPFQREDRNSSP---QIKVNLNFIKRPPKNTSAPSQQEP---DRFDRDRLFSVVSRG 87 PM+S F E + P + K +++ N+ APS P F+R LF +VSRG Sbjct: 98 PMDSLFGYETYHHHPTENRRKRKKILLEKENLNSQAPSPDPPPVIKMFNRHMLFDIVSRG 157 Query: 88 VPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSG 147 EL G L +L K LTD + E STGKTCL KA++NL G N I L+ I + +G Sbjct: 158 STAELEGFLPFLLAQKKRLTDEEFREASTGKTCLTKALMNLNGGKNDTIPMLIDIAEKTG 217 Query: 148 NPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQ-KHQGTC 206 N + +N+ D +Y+G +ALHIAIE+R V+LLVE GADVH +A GRFFQ K +G Sbjct: 218 NLREFINSPFRDVYYRGQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGY 277 Query: 207 FYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSAL 266 FYFGELPLSLAACT Q D+V YL EN H+ A + DS GNTVLHALV IADN+ EN+ Sbjct: 278 FYFGELPLSLAACTNQPDIVHYLTENAHKKADIRRQDSRGNTVLHALVAIADNTRENTKF 337 Query: 267 VIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQREFSGP-YQP 325 V +YD L+ +L P LE I N+ ++PL +AAK GKI IF+HI++ E + Sbjct: 338 VTKVYDLLVIKCVKLYPDSSLEAIFNNDSMSPLMMAAKLGKIGIFQHIIRLEIKDEEARH 397 Query: 326 LSRKFTEWCYGPVRVSLYDLSSVDSW-EKNSVLEIIAFHCKSPNRHRMVVLEPLNKLLQE 384 LSRKF +W YGPV SLYDLS +D+ E+ SVLEI+ ++ K NRH M+ +EP+N+LL++ Sbjct: 398 LSRKFRDWAYGPVYSSLYDLSMLDTCGEEVSVLEILVYNSKVENRHEMLAVEPINELLRD 457 Query: 385 KWDRL-VSRFFFNFACYLVYMFIFTVVAYHQPSLDQPAIPSSKATFGESMLLLGHILILL 443 KW + F+ + YL+ M IFT++AY++P P P T + M L G I+ LL Sbjct: 458 KWQKFGAVSFYISVVSYLIAMIIFTLIAYYRPMDGTPPYPYR--TTMDYMRLAGEIVTLL 515 Query: 444 GGIYLLLGQLW-YFWRRRLFIWISFMDSYFEILFLLQALLTVLSQVLRFMETEWYLPLLV 502 G+ + + F ++ + F+D F++L+ + ++L +++ VL + E YL ++V Sbjct: 516 TGVVFFITNIKDLFMKKCPGVNSLFIDGSFQLLYFIYSVLVIITAVLYLVGIESYLAVMV 575 Query: 503 LSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVSLSREA 562 +LVLGW+N LY+TRG + TG YS+M+QK++ +DL RFLLVYL+F+ G+A ALVSL Sbjct: 576 FALVLGWMNALYFTRGLKLTGTYSIMLQKILFKDLFRFLLVYLLFMIGYASALVSLLNPC 635 Query: 563 RSPKA--PEDNNSTVTEQPTVGQEEEPAPYRSILDASLELFKFTIGMGELAFQEQLRFRG 620 S ++ +N TV E P+ + + + L L+LFK TIGMG+L ++ Sbjct: 636 TSQESCIETSSNCTVPEYPSC---RDSSTFSKFL---LDLFKLTIGMGDLEMINSAKYPA 689 Query: 621 VVLLLLLAYVLLTYVLLLNMLIALMSETVNHVADNSWSIWKLQKAISVLEMENGYWWCRR 680 V ++LL+ Y++LT+VLLLNMLIALM ETV V+ S IWKLQ A ++L++E + C R Sbjct: 690 VFIILLVTYIILTFVLLLNMLIALMGETVGQVSKESKQIWKLQWATTILDIERSFPVCMR 749 Query: 681 KKHREGRLLKVGTRGDGTPDERWCFRVEEVNWAAWEKTLPTLSEDP 726 K R G ++ VG DGTPD RWCFRV+EVNW+ W + L ++EDP Sbjct: 750 KAFRSGEMVTVGKNLDGTPDRRWCFRVDEVNWSHWNQNLGIINEDP 795 >6C8G-A nrPDB Length = 675 Score = 572 bits (1473), Expect = e-163, Method: Compositional matrix adjust. Identities = 309/671 (46%), Positives = 429/671 (63%), Gaps = 18/671 (2%) Query: 66 APSQQEP---DRFDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLM 122 APS P F+R LF +VSRG EL G L +L K LTD + E STGKTCL Sbjct: 2 APSPDPPPVIKMFNRHMLFDIVSRGSTAELEGFLPFLLAQKKRLTDEEFREASTGKTCLT 61 Query: 123 KAVLNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKL 182 KA++NL G N I L+ I + +GN + +N+ D +Y+G +ALHIAIE+R V+L Sbjct: 62 KALMNLNGGKNDTIPMLIDIAEKTGNLREFINSPFRDVYYRGQTALHIAIERRCKHYVEL 121 Query: 183 LVENGADVHLRACGRFFQ-KHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEA 241 LVE GADVH +A GRFFQ K +G FYFGELPLSLAACT Q D+V YL EN H+ A + Sbjct: 122 LVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPDIVHYLTENAHKKADIRR 181 Query: 242 TDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKL 301 DS GNTVLHALV IADN+ EN+ V +YD L+ +L P LE I N+ ++PL + Sbjct: 182 QDSRGNTVLHALVAIADNTRENTKFVTKVYDLLVIKCVKLYPDSSLEAIFNNDSMSPLMM 241 Query: 302 AAKEGKIEIFRHILQREFSGP-YQPLSRKFTEWCYGPVRVSLYDLSSVDSW-EKNSVLEI 359 AAK GKI IF+HI++ E + LSRKF +W YGPV SLYDLS +D+ E+ SVLEI Sbjct: 242 AAKLGKIGIFQHIIRLEIKDEEARHLSRKFRDWAYGPVYSSLYDLSMLDTCGEEVSVLEI 301 Query: 360 IAFHCKSPNRHRMVVLEPLNKLLQEKWDRL-VSRFFFNFACYLVYMFIFTVVAYHQPSLD 418 + ++ K NRH M+ +EP+N+LL++KW + F+ + YL+ M IFT++AY++P Sbjct: 302 LVYNSKVENRHEMLAVEPINELLRDKWQKFGAVSFYISVVSYLIAMIIFTLIAYYRPMDG 361 Query: 419 QPAIPSSKATFGESMLLLGHILILLGGIYLLLGQLW-YFWRRRLFIWISFMDSYFEILFL 477 P P T + M L G I+ LL G+ + + F ++ + F+D F++L+ Sbjct: 362 TPPYPYR--TTMDYMRLAGEIVTLLTGVVFFITNIKDLFMKKCPGVNSLFIDGSFQLLYF 419 Query: 478 LQALLTVLSQVLRFMETEWYLPLLVLSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDL 537 + ++L +++ VL + E YL ++V +LVLGW+N LY+TRG + TG YS+M+QK++ +DL Sbjct: 420 IYSVLVIITAVLYLVGIESYLAVMVFALVLGWMNALYFTRGLKLTGTYSIMLQKILFKDL 479 Query: 538 LRFLLVYLVFLFGFAVALVSLSREARSPKAPEDNNS--TVTEQPTVGQEEEPAPYRSILD 595 RFLLVYL+F+ G+A ALVSL S ++ + +S TV E P+ + + + L Sbjct: 480 FRFLLVYLLFMIGYASALVSLLNPCTSQESCIETSSQCTVPEYPSC---RDSSTFSKFL- 535 Query: 596 ASLELFKFTIGMGELAFQEQLRFRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNHVADN 655 L+LFK TIGMG+L ++ V ++LL+ Y++LT+VLLLNMLIALM ETV V+ Sbjct: 536 --LDLFKLTIGMGDLEMINSAKYPAVFIILLVTYIILTFVLLLNMLIALMGETVGQVSKE 593 Query: 656 SWSIWKLQKAISVLEMENGYWWCRRKKHREGRLLKVGTRGDGTPDERWCFRVEEVNWAAW 715 S IWKLQ A ++L++E + C RK R G ++ VG DGTPD RWCFRV+EVNW+ W Sbjct: 594 SKQIWKLQWATTILDIERSFPVCMRKAFRSGEMVTVGKNLDGTPDRRWCFRVDEVNWSHW 653 Query: 716 EKTLPTLSEDP 726 + L ++EDP Sbjct: 654 NQNLGIINEDP 664 >2ETB-A nrPDB Length = 256 Score = 514 bits (1325), Expect = e-146, Method: Compositional matrix adjust. Identities = 246/247 (99%), Positives = 246/247 (99%) Query: 75 FDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNA 134 FDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNA Sbjct: 1 FDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNA 60 Query: 135 CIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRA 194 CIMPLLQIDKDSGNPK LVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRA Sbjct: 61 CIMPLLQIDKDSGNPKPLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRA 120 Query: 195 CGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALV 254 CGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALV Sbjct: 121 CGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALV 180 Query: 255 MIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHI 314 MIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHI Sbjct: 181 MIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHI 240 Query: 315 LQREFSG 321 LQREFSG Sbjct: 241 LQREFSG 247 >2F37-A nrPDB Length = 251 Score = 452 bits (1164), Expect = e-127, Method: Compositional matrix adjust. Identities = 215/250 (86%), Positives = 231/250 (92%) Query: 71 EPDRFDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQD 130 +P+RFDRDRLF+ VSRGVPE+L GL EYL SKYLTDS YTEGSTGKTCLMKAVLNL+D Sbjct: 2 DPNRFDRDRLFNAVSRGVPEDLAGLPEYLSKTSKYLTDSEYTEGSTGKTCLMKAVLNLKD 61 Query: 131 GVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADV 190 GVNACI+PLLQID+DSGNP+ LVNAQCTD++Y+GHSALHIAIEKRSLQCVKLLVENGA+V Sbjct: 62 GVNACILPLLQIDRDSGNPQPLVNAQCTDDYYRGHSALHIAIEKRSLQCVKLLVENGANV 121 Query: 191 HLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVL 250 H RACGRFFQK QGTCFYFGELPLSLAACTKQWDVV+YLLENPHQPASL+ATDS GNTVL Sbjct: 122 HARACGRFFQKGQGTCFYFGELPLSLAACTKQWDVVSYLLENPHQPASLQATDSQGNTVL 181 Query: 251 HALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEI 310 HALVMI+DNS EN ALV MYDGLLQ GARLCPTVQLE+I N Q LTPLKLAAKEGKIEI Sbjct: 182 HALVMISDNSAENIALVTSMYDGLLQAGARLCPTVQLEDIRNLQDLTPLKLAAKEGKIEI 241 Query: 311 FRHILQREFS 320 FRHILQREFS Sbjct: 242 FRHILQREFS 251 >6DVZ-A nrPDB Length = 791 Score = 444 bits (1141), Expect = e-125, Method: Compositional matrix adjust. Identities = 293/741 (39%), Positives = 403/741 (54%), Gaps = 83/741 (11%) Query: 29 KQEPP----PMESPFQR------EDRNS--SPQIKVNLNFIKRPPKNTSAPSQQEPDR-- 74 K PP PM+S ++ +D +S SPQ V P N ++PS Sbjct: 58 KTSPPIFSKPMDSNIRQCLSGNCDDMDSPQSPQDDVT-----ETPSNPNSPSANLAKEEQ 112 Query: 75 -----FDRDRLFSVVSRGVPEELTGLLEYL-----RWNSKYLTD---SAYTEGSTGKTCL 121 + R+F+ VS G EEL LL+ L R + D T TGKTCL Sbjct: 113 RQKKKRLKKRIFAAVSEGCVEELRELLQDLQDLCRRRRGLDVPDFLMHKLTASDTGKTCL 172 Query: 122 MKAVLNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVK 181 MKA+LN+ + LL +++ +NA+ T+E Y+G +AL+IAIE+R Sbjct: 173 MKALLNINPNTKEIVRILLAFAEENDILDRFINAEYTEEAYEGQTALNIAIERRQGDITA 232 Query: 182 LLVENGADVHLRACGRFFQ-KHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLE 240 +L+ GADV+ A G FF K+Q FYFGE PL+LAACT Q ++V L+EN + + Sbjct: 233 VLIAAGADVNAHAKGVFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMEN--EQTDIT 290 Query: 241 ATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLK 300 + DS GN +LHALV +A++ + V MYD +L +LE + N+ GLTPL+ Sbjct: 291 SQDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILLRSGNW----ELETMRNNDGLTPLQ 346 Query: 301 LAAKEGKIEIFRHILQREFS-GPYQPLSRKFTEWCYGPVRVSLYDLSSVDSWEKNSVLEI 359 LAAK GK EI ++IL RE P + LSRKFT+W YGPV SLYDL++VD+ NSVLEI Sbjct: 347 LAAKMGKAEILKYILSREIKEKPLRSLSRKFTDWAYGPVSSSLYDLTNVDTTTDNSVLEI 406 Query: 360 IAFHCKSPNRHRMVVLEPLNKLLQEKWDRLVSRFFFNFACYLV---------YMFIFTVV 410 I ++ NRH M+ LEPL+ LL KW + FA Y+ Y T+V Sbjct: 407 IVYNTNIDNRHEMLTLEPLHTLLHTKWKK--------FAKYMFFLSFCFYFFYNITLTLV 458 Query: 411 AYHQPSLDQPAIPSSKATFGESML-LLGHILILLGGIYLLLGQ-LWYFWRRRLFIWISFM 468 +Y++P D+ T S L LLG + +L+ + + + + F R + Sbjct: 459 SYYRPREDEDLPHPLALTHKMSWLQLLGRMFVLIWATCISVKEGIAIFLLRPSDLQSILS 518 Query: 469 DSYFEILFLLQALLTVLSQVLRFMETEWYLPLLVLSLVLGWLNLLYYTRGFQHTGIYSVM 528 D++F +F +QA+L +LS L + YL LVL++ LGW N+L YTRGFQ G+YSVM Sbjct: 519 DAWFHFVFFVQAVLVILSVFLYLFAYKEYLACLVLAMALGWANMLAYTRGFQSMGMYSVM 578 Query: 529 IQKVILRDLLRFLLVYLVFLFGFAVALVSLSREARSPKAPEDNNSTVTEQPTVGQEEEPA 588 IQKVIL D+L+FL VY++FL GF VAL SL + K ++ + Sbjct: 579 IQKVILHDVLKFLFVYILFLLGFGVALASLIEKCSKDK------------------KDCS 620 Query: 589 PYRSILDASLELFKFTIGMGELAFQEQLRFRGVVLLLLLAYVLLTYVLLLNMLIALMSET 648 Y S DA LELFK TIG+G+L Q+ + + L LL+ YV+LT+VLLLNMLIALM ET Sbjct: 621 SYGSFSDAVLELFKLTIGLGDLNIQQNSTYPILFLFLLITYVILTFVLLLNMLIALMGET 680 Query: 649 VNHVADNSWSIWKLQKAISVLEMENGYWWCRRKKHREGRLLKVGTRGDGTPDERWCFRVE 708 V +V+ S IW+LQ+A ++LE E R + R G L KV D R C R+ Sbjct: 681 VENVSKESERIWRLQRARTILEFEKMLPEWLRSRFRMGELCKVADE-----DFRLCLRIN 735 Query: 709 EVNWAAWEKTLPTLSEDPSGP 729 EV W W+ + L+EDP GP Sbjct: 736 EVKWTEWKTHVSFLNEDP-GP 755 >6MHW-A nrPDB Length = 826 Score = 435 bits (1118), Expect = e-122, Method: Compositional matrix adjust. Identities = 275/656 (41%), Positives = 379/656 (57%), Gaps = 45/656 (6%) Query: 112 TEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIA 171 T TGKTCLMKA+LN+ + LL +++ +NA+ T+E Y+G +AL+IA Sbjct: 164 TASDTGKTCLMKALLNINPNTKEIVRILLAFAEENDILGRFINAEYTEEAYEGQTALNIA 223 Query: 172 IEKRSLQCVKLLVENGADVHLRACGRFFQ-KHQGTCFYFGELPLSLAACTKQWDVVTYLL 230 IE+R LL+ GADV+ A G FF K+Q FYFGE PL+LAACT Q ++V L+ Sbjct: 224 IERRQGDIAALLIAAGADVNAHAKGAFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLM 283 Query: 231 ENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEI 290 E H+ + + DS GN +LHALV +A++ + V MYD +L +LE Sbjct: 284 E--HEQTDITSRDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILLRSGNW----ELETT 337 Query: 291 SNHQGLTPLKLAAKEGKIEIFRHILQREFSGP-YQPLSRKFTEWCYGPVRVSLYDLSSVD 349 N+ GLTPL+LAAK GK EI ++IL RE + LSRKFT+W YGPV SLYDL++VD Sbjct: 338 RNNDGLTPLQLAAKMGKAEILKYILSREIKEKRLRSLSRKFTDWAYGPVSSSLYDLTNVD 397 Query: 350 SWEKNSVLEIIAFHCKSPNRHRMVVLEPLNKLLQEKWDRLVSRFFFNFACYLV-YMFIFT 408 + NSVLEI ++ NRH M+ LEPL+ LL KW + FF C+ Y T Sbjct: 398 TTTDNSVLEITVYNTNIDNRHEMLTLEPLHTLLHMKWKKFAKHMFFLSFCFYFFYNITLT 457 Query: 409 VVAYHQPSLDQPAIPSSKATFGES--MLLLGHILILLGGIYLLLGQ-LWYFWRRRLFIWI 465 +V+Y++P ++ AIP A + + LLG + +L+ + + + + + F R + Sbjct: 458 LVSYYRPR-EEEAIPHPLALTHKMGWLQLLGRMFVLIWAMCISVKEGIAIFLLRPSDLQS 516 Query: 466 SFMDSYFEILFLLQALLTVLSQVLRFMETEWYLPLLVLSLVLGWLNLLYYTRGFQHTGIY 525 D++F +F +QA+L +LS L + YL LVL++ LGW N+LYYTRGFQ G+Y Sbjct: 517 ILSDAWFHFVFFIQAVLVILSVFLYLFAYKEYLACLVLAMALGWANMLYYTRGFQSMGMY 576 Query: 526 SVMIQKVILRDLLRFLLVYLVFLFGFAVALVSLSREARSPKAPEDNNSTVTEQPTVGQEE 585 SVMIQKVIL D+L+FL VY+VFL GF VAL SL K P+DN + Sbjct: 577 SVMIQKVILHDVLKFLFVYIVFLLGFGVALASLIE-----KCPKDN-------------K 618 Query: 586 EPAPYRSILDASLELFKFTIGMGELAFQEQLRFRGVVLLLLLAYVLLTYVLLLNMLIALM 645 + + Y S DA LELFK TIG+G+L Q+ ++ + L LL+ YV+LT+VLLLNMLIALM Sbjct: 619 DCSSYGSFSDAVLELFKLTIGLGDLNIQQNSKYPILFLFLLITYVILTFVLLLNMLIALM 678 Query: 646 SETVNHVADNSWSIWKLQKAISVLEMENGYWWCRRKKHREGRLLKVGTRGDGTPDERWCF 705 ETV +V+ S IW+LQ+A ++LE E R + R G L KV D R C Sbjct: 679 GETVENVSKESERIWRLQRARTILEFEKMLPEWLRSRFRMGELCKV-----AEDDFRLCL 733 Query: 706 RVEEVNWAAWEKTLPTLSEDPSGP-------GITGNKKNPTSKPGKNSASEEDHLP 754 R+ EV W W+ + L+EDP GP I + +N SK N+ E + P Sbjct: 734 RINEVKWTEWKTHVSFLNEDP-GPVRRTDFNKIQDSSRN-NSKTTLNAFEEVEEFP 787 >2NYJ-A nrPDB Length = 273 Score = 261 bits (666), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 132/258 (51%), Positives = 179/258 (69%), Gaps = 1/258 (0%) Query: 66 APSQQEPDRFDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAV 125 + ++ P +DR +F V++ +EL LL +L+ + K LTDS + + TGKTCL+KA+ Sbjct: 3 SAGEKPPRLYDRRSIFDAVAQSNCQELESLLPFLQRSKKRLTDSEFKDPETGKTCLLKAM 62 Query: 126 LNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVE 185 LNL +G N I LL + + + + K VNA TD +Y+G +ALHIAIE+R++ V LLVE Sbjct: 63 LNLHNGQNDTIALLLDVARKTDSLKQFVNASYTDSYYKGQTALHIAIERRNMTLVTLLVE 122 Query: 186 NGADVHLRACGRFFQKHQGT-CFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDS 244 NGADV A G FF+K +G FYFGELPLSLAACT Q +V +LL+N QPA + A DS Sbjct: 123 NGADVQAAANGDFFKKTKGRPGFYFGELPLSLAACTNQLAIVKFLLQNSWQPADISARDS 182 Query: 245 LGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAK 304 +GNTVLHALV +ADN+ +N+ V MY+ +L +GA+L PT++LEEI+N +GLTPL LAA Sbjct: 183 VGNTVLHALVEVADNTVDNTKFVTSMYNEILILGAKLHPTLKLEEITNRKGLTPLALAAS 242 Query: 305 EGKIEIFRHILQREFSGP 322 GKI + +ILQRE P Sbjct: 243 SGKIGVLAYILQREIHEP 260 >4DX2-A nrPDB Length = 259 Score = 257 bits (657), Expect = 1e-68, Method: Compositional matrix adjust. Identities = 136/247 (55%), Positives = 169/247 (68%), Gaps = 1/247 (0%) Query: 75 FDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNA 134 F+R LF +VSRG +L GLL +L + K LTD + E STGKTCL KA+LNL +G N Sbjct: 2 FNRPILFDIVSRGSTADLDGLLPFLLTHKKRLTDEEFREPSTGKTCLPKALLNLSNGRND 61 Query: 135 CIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRA 194 I LL I + +GN + +N+ D +Y+G +ALHIAIE+R V+LLV GADVH +A Sbjct: 62 TIPVLLDIAERTGNMREFINSPFRDIYYRGQTALHIAIERRCKHYVELLVAQGADVHAQA 121 Query: 195 CGRFFQ-KHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHAL 253 GRFFQ K +G FYFGELPLSLAACT Q +V YL ENPH+ A + DS GNTVLHAL Sbjct: 122 RGRFFQPKDEGGYFYFGELPLSLAACTNQPHIVNYLTENPHKKADMRRQDSRGNTVLHAL 181 Query: 254 VMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRH 313 V IADN+ EN+ V MYD LL ARL P LE + N+ GL+PL +AAK GKI IF+H Sbjct: 182 VAIADNTRENTKFVTKMYDLLLLKCARLFPDSNLEAVLNNDGLSPLMMAAKTGKIGIFQH 241 Query: 314 ILQREFS 320 I++RE + Sbjct: 242 IIRREVT 248 >3W9G-A nrPDB Length = 260 Score = 257 bits (656), Expect = 2e-68, Method: Compositional matrix adjust. Identities = 137/247 (55%), Positives = 169/247 (68%), Gaps = 1/247 (0%) Query: 75 FDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNA 134 F+R LF +VSRG P+ L GLL +L + K LTD + E STGKTCL KA+LNL G N Sbjct: 4 FNRPILFDIVSRGSPDGLEGLLSFLLTHKKRLTDEEFREPSTGKTCLPKALLNLSAGRND 63 Query: 135 CIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRA 194 I LL I + +GN + +N+ D +Y+G +ALHIAIE+R V+LLVE GADVH +A Sbjct: 64 TIPILLDIAEKTGNMREFINSPFRDVYYRGQTALHIAIERRCKHYVELLVEKGADVHAQA 123 Query: 195 CGRFFQ-KHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHAL 253 GRFFQ K +G FYFGELPLSLAACT Q +V YL EN H+ A L DS GNTVLHAL Sbjct: 124 RGRFFQPKDEGGYFYFGELPLSLAACTNQPHIVHYLTENGHKQADLRRQDSRGNTVLHAL 183 Query: 254 VMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRH 313 V IADN+ EN+ V MYD LL A+L P LE + N+ GL+PL +AAK GKI IF+H Sbjct: 184 VAIADNTRENTKFVTKMYDLLLIKCAKLFPDTNLEALLNNDGLSPLMMAAKTGKIGIFQH 243 Query: 314 ILQREFS 320 I++RE + Sbjct: 244 IIRREIA 250 >6BOA-A nrPDB Length = 742 Score = 234 bits (597), Expect = 1e-61, Method: Compositional matrix adjust. Identities = 187/633 (29%), Positives = 301/633 (47%), Gaps = 90/633 (14%) Query: 104 KYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQ 163 KY + G+ G+T L A L D + A ++ + P+L+ T E Y+ Sbjct: 66 KYEDCKVHQRGAMGETALHIAAL--YDNLEAAMVLM------EAAPELVFEPM-TSELYE 116 Query: 164 GHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQW 223 G +ALHIA+ +++ V+ L+ A V RA G F++ YFGE PLS AAC Sbjct: 117 GQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSE 176 Query: 224 DVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLL---QMGAR 280 ++V L+E+ A + A DSLGNTVLH L++ N MY+ LL + G Sbjct: 177 EIVRLLIEHG---ADIRAQDSLGNTVLHILIL-----QPNKTFACQMYNLLLSYDRHGDH 228 Query: 281 LCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQREFSGPYQPLSRKFTEWCYGPVRV 340 L P L+ + NHQGLTP KLA EG +F+H++Q+ RK T+W YGP+ Sbjct: 229 LQP---LDLVPNHQGLTPFKLAGVEGNTVMFQHLMQK----------RKHTQWTYGPLTS 275 Query: 341 SLYDLSSVDS-WEKNSVLEIIAFHCKSPNRHRMVVLEPLNKLLQEKWDRLVSRFFFNF-A 398 +LYDL+ +DS ++ S+LE+I K R +++ P+ +L+ KW R +F A Sbjct: 276 TLYDLTEIDSSGDEQSLLELIITTKKREAR-QILDQTPVKELVSLKWKRYGRPYFCMLGA 334 Query: 399 CYLVYMFIFTVVAYHQPS---------------LDQPAIPSSKATFGESMLLLGHILILL 443 YL+Y+ FT+ ++P L Q + + T + + L+G ++ ++ Sbjct: 335 IYLLYIICFTMCCIYRPLKPRTNNRTSPRDNTLLQQKLLQEAYMTPKDDIRLVGELVTVI 394 Query: 444 GGIYLLLGQLWYFWRRRL--FIWISFMDSYFEILFLLQALLTVLSQVLRFMETEWYLPLL 501 G I +LL ++ +R + F + + F +L + A + +++ V+R + + + Sbjct: 395 GAIIILLVEVPDIFRMGVTRFFGQTILGGPFHVLIITYAFMVLVTMVMRLISASGEVVPM 454 Query: 502 VLSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVSLSRE 561 +LVLGW N++Y+ GFQ G +++MIQK+I DL+RF + V + GFA A Sbjct: 455 SFALVLGWCNVMYFAEGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFY----- 509 Query: 562 ARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDASLELFK-----FTIGMGELAFQEQL 616 + Q E+P D + LF TI G + L Sbjct: 510 ------------------IIFQTEDPEELGHFYDYPMALFSTFELFLTIIDGPANYNVDL 551 Query: 617 RFRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNHVADNSWSIWKLQKAISVLEMENGYW 676 F + + A+ ++ +L+LN+LIA+M +T VA +W+ Q + + +E Sbjct: 552 PF--MYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVATTVMLERKLP 609 Query: 677 WCRRKKHREGRLLKVGTRGDGTPDERWCFRVEE 709 C R G + R G D RW RVE+ Sbjct: 610 RCLWP--RSG----ICGREYGLGD-RWFLRVED 635 >6DMR-A nrPDB Length = 730 Score = 228 bits (582), Expect = 6e-60, Method: Compositional matrix adjust. Identities = 172/580 (29%), Positives = 281/580 (48%), Gaps = 71/580 (12%) Query: 114 GSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIE 173 G+ G+T L A L D + A + + + + P L E + G +ALHIA+ Sbjct: 76 GAVGETALHVAAL--YDNLEAATLLMEAAPELAKEPALC-------EPFVGQTALHIAVM 126 Query: 174 KRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENP 233 ++L V+ L+ GA V RA G F++ Y+GE PLS AAC ++V L+E+ Sbjct: 127 NQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHG 186 Query: 234 HQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNH 293 A + A DSLGNTVLH L++ N MY+ LL LE + NH Sbjct: 187 ---ADIRAQDSLGNTVLHILIL-----QPNKTFACQMYNLLLSYDEHSDHLQSLELVPNH 238 Query: 294 QGLTPLKLAAKEGKIEIFRHILQREFSGPYQPLSRKFTEWCYGPVRVSLYDLSSVDSW-E 352 QGLTP KLA EG +F+H++Q+ RK +W GP+ +LYDL+ +DSW E Sbjct: 239 QGLTPFKLAGVEGNTVMFQHLMQK----------RKHVQWTCGPLTSTLYDLTEIDSWGE 288 Query: 353 KNSVLEIIAFHCKSPNRHRMVVLE--PLNKLLQEKWDRLVSRFFFNFAC-YLVYMFIFTV 409 + S LE++ S R +LE P+ +L+ KW + +F A Y++YM FT Sbjct: 289 ELSFLELVV---SSKKREARQILEQTPVKELVSFKWKKYGRPYFCVLASLYILYMICFTT 345 Query: 410 VAYHQP---------------SLDQPAIPSSKATFGESMLLLGHILILLGGIYLLLGQLW 454 ++P L Q + + T +++ L+G ++ + G + +LL ++ Sbjct: 346 CCIYRPLKLRDDNRTDPRDITILQQKLLQEAYVTHQDNIRLVGELVTVTGAVIILLLEIP 405 Query: 455 YFWR--RRLFIWISFMDSYFEILFLLQALLTVLSQVLRFMETEWYLPLLVLSLVLGWLNL 512 +R + + + F ++ + A L +L+ V+R + L +LVLGW ++ Sbjct: 406 DIFRVGASRYFGQTILGGPFHVIIITYASLVLLTMVMRLTNMNGEVVPLSFALVLGWCSV 465 Query: 513 LYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVSLSREARSPKAPEDNN 572 +Y+ RGFQ G +++MIQK+I DL+RF + V + GFA A ++ + P +N Sbjct: 466 MYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAF-HITFQTEDP----NNL 520 Query: 573 STVTEQPTVGQEEEPAPYRSILDASLELFKFTIGMGELAFQEQLRFRGVVLLLLLAYVLL 632 ++ PT L ++ ELF TI G + L F + + A+ ++ Sbjct: 521 GEFSDYPTA------------LFSTFELF-LTIIDGPANYSVDLPF--MYCITYAAFAII 565 Query: 633 TYVLLLNMLIALMSETVNHVADNSWSIWKLQKAISVLEME 672 +L+LN+ IA+M +T VA +W+ Q + + +E Sbjct: 566 ATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVATTVMLE 605 >6E2G-A nrPDB Length = 727 Score = 226 bits (577), Expect = 2e-59, Method: Compositional matrix adjust. Identities = 183/632 (28%), Positives = 300/632 (47%), Gaps = 89/632 (14%) Query: 104 KYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQ 163 K+ + +G+ G+T L A L D + A ++ + P+L+ T E Y+ Sbjct: 66 KFEGCEVHQKGAMGETALHIAAL--YDNLEAAMVLM------EAAPELVFEPM-TSELYE 116 Query: 164 GHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQW 223 G +ALHIA+ +++ V+ L+ GA V RA G F Y+GE PLS AAC Sbjct: 117 GQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSE 176 Query: 224 DVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQM--GARL 281 ++V L+E+ A + A DSLGNTVLH L++ N MY+ LL G L Sbjct: 177 EIVRLLIEHG---ADIRAQDSLGNTVLHILIL-----QPNKTFACQMYNLLLSYDGGDHL 228 Query: 282 CPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQREFSGPYQPLSRKFTEWCYGPVRVS 341 LE + N+QGLTP KLA EG I +F+H++Q+ RK +W YGP+ + Sbjct: 229 ---KSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQK----------RKHIQWTYGPLTST 275 Query: 342 LYDLSSVDS-WEKNSVLEIIAFHCKSPNRHRMVVLEPLNKLLQEKWDRLVSRFFFNF-AC 399 LYDL+ +DS + S+LE+I K R +++ P+ +L+ KW R +F A Sbjct: 276 LYDLTEIDSSGDDQSLLELIVTTKKREAR-QILDQTPVKELVSLKWKRYGRPYFCVLGAI 334 Query: 400 YLVYMFIFTVVAYHQPS---------------LDQPAIPSSKATFGESMLLLGHILILLG 444 Y++Y+ FT+ ++P L Q + + T + + L+G ++ ++G Sbjct: 335 YVLYIICFTMCCVYRPLKPRITNRTNPRDNTLLQQKLLQEAYVTPKDDLRLVGELVSIVG 394 Query: 445 GIYLLLGQLWYFWRRRL--FIWISFMDSYFEILFLLQALLTVLSQVLRFMETEWYLPLLV 502 + +LL ++ +R + F + + F ++ + A + +++ V+R ++ + + Sbjct: 395 AVIILLVEIPDIFRLGVTRFFGQTILGGPFHVIIVTYAFMVLVTMVMRLTNSDGEVVPMS 454 Query: 503 LSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVSLSREA 562 +LVLGW N++Y+ RGFQ G +++MIQK+I DL+RF + V + GFA A Sbjct: 455 FALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFY------ 508 Query: 563 RSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDASLELFK-----FTIGMGELAFQEQLR 617 + Q E+P D + LF TI G + L Sbjct: 509 -----------------IIFQTEDPDELGHFYDYPMALFSTFELFLTIIDGPANYDVDLP 551 Query: 618 FRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNHVADNSWSIWKLQKAISVLEMENGYWW 677 F + + A+ ++ +L+LN+LIA+M +T VA +W+ Q + + +E Sbjct: 552 F--MYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQVVATTVMLERKLPR 609 Query: 678 CRRKKHREGRLLKVGTRGDGTPDERWCFRVEE 709 C R G + R G D RW RVE+ Sbjct: 610 CLWP--RSG----ICGREYGLGD-RWFLRVED 634 >4N5Q-A nrPDB Length = 257 Score = 168 bits (425), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 103/253 (40%), Positives = 144/253 (56%), Gaps = 15/253 (5%) Query: 77 RDRLFSVVSRGVPEELTGLLEYL-----RWNSKYLTD---SAYTEGSTGKTCLMKAVLNL 128 + R+F+ VS G EEL LL+ L R + D T TGKTCLMKA+LN+ Sbjct: 4 KKRIFAAVSEGCVEELRELLQDLQDLCRRRRGLDVPDFLMHKLTASDTGKTCLMKALLNI 63 Query: 129 QDGVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGA 188 + LL +++ +NA+ T+E Y+G +AL+IAIE+R +L+ GA Sbjct: 64 NPNTKEIVRILLAFAEENDILDRFINAEYTEEAYEGQTALNIAIERRQGDITAVLIAAGA 123 Query: 189 DVHLRACGRFFQ-KHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGN 247 DV+ A G FF K+Q FYFGE PL+LAACT Q ++V L+EN + + + DS GN Sbjct: 124 DVNAHAKGVFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMEN--EQTDITSQDSRGN 181 Query: 248 TVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGK 307 +LHALV +A++ + V MYD +L +LE + N+ GLTPL+LAAK GK Sbjct: 182 NILHALVTVAEDFKTQNDFVKRMYDMILLRSGNW----ELETMRNNDGLTPLQLAAKMGK 237 Query: 308 IEIFRHILQREFS 320 EI ++IL RE Sbjct: 238 AEILKYILSREIK 250 >2RFA-A nrPDB Length = 232 Score = 111 bits (277), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 78/209 (37%), Positives = 109/209 (52%), Gaps = 22/209 (10%) Query: 111 YTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHI 170 + G+ G+T L A L D + A M L++ + LV T E Y+G +ALHI Sbjct: 31 HQRGAMGETALHIAAL--YDNLEAA-MVLMEAAPE------LVFEPMTSELYEGQTALHI 81 Query: 171 AIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLL 230 A+ +++ V+ L+ GA V RA G F Y+GE PLS AAC ++V L+ Sbjct: 82 AVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLI 141 Query: 231 ENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQM--GARLCPTVQLE 288 E+ A + A DSLGNTVLH L++ N MY+ LL G L LE Sbjct: 142 EH---GADIRAQDSLGNTVLHILIL-----QPNKTFACQMYNLLLSYDGGDHL---KSLE 190 Query: 289 EISNHQGLTPLKLAAKEGKIEIFRHILQR 317 + N+QGLTP KLA EG I +F+H++Q+ Sbjct: 191 LVPNNQGLTPFKLAGVEGNIVMFQHLMQK 219 >6G1K-A nrPDB Length = 921 Score = 49.7 bits (117), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 58/242 (23%), Positives = 103/242 (42%), Gaps = 29/242 (11%) Query: 442 LLGGIYLLLGQLWYF-WRRRLFIWISFMDSYFEILFLLQALLTVLSQV----LRFMET-E 495 +LG I+ + Q+W ++ + W + MD L+L L +++ V + +T E Sbjct: 410 VLGFIWTEIKQMWDGGFQDYIHDWWNLMDFVMNSLYLATISLKIVAYVKYSGCKPRDTWE 469 Query: 496 WYLPLLVLSLVLGWLNLLYYTR------GFQHTGIYSVMIQKVILRDLLRFLLVYLVFLF 549 + P LV V N+ R H G + + +++L D+L+FL +Y + L Sbjct: 470 MWHPTLVAEAVFAIANIFSSLRLISLFTANSHLGPLQISLGRMLL-DILKFLFIYCLVLL 528 Query: 550 GFAVALVSLSREARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDASLELFKFTIGMGE 609 FA L L NS + E + + ++ + LF G+ Sbjct: 529 AFANGLNQLYFYYE--------NSEGMTCKGIRCERQNNAFSTLFETLQSLFWSIFGLIS 580 Query: 610 L------AFQEQLRFRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNHVADNSWSIWKLQ 663 L A + F G + Y +++ V+LLNMLIA+M+ + H+AD++ WK Sbjct: 581 LYVTNVKADHKFTEFVGATMFG--TYNVISLVVLLNMLIAMMNNSYQHIADHADIEWKFA 638 Query: 664 KA 665 + Sbjct: 639 RT 640 >5AQ7-A nrPDB Length = 418 Score = 42.4 bits (98), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 48/161 (29%), Positives = 68/161 (42%), Gaps = 33/161 (20%) Query: 151 LLVN-AQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYF 209 LL N A G + LH+A + L V++L++NGADV+ Sbjct: 33 LLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADVN-------------ANDER 79 Query: 210 GELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIH 269 G PL LAA T ++V LL+N A + ATD +G LH M Sbjct: 80 GHTPLHLAAYTGHLEIVEVLLKN---GAGVNATDVIGTAPLHLAAMWG---------YKE 127 Query: 270 MYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEI 310 + + LL+ GA + + + G PL LAA +G EI Sbjct: 128 IVEVLLKAGADV-------DAQDKFGKRPLWLAADQGHAEI 161 >5Z96-A nrPDB Length = 755 Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust. Identities = 40/172 (23%), Positives = 73/172 (42%), Gaps = 17/172 (9%) Query: 500 LLVLSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVSLS 559 L ++ + L L+ H G + + +++L D+L+FL +Y + L FA L L Sbjct: 480 LFAIANIFSSLRLISLFTANSHLGPLQISLGRMLL-DILKFLFIYCLVLLAFANGLNQLY 538 Query: 560 REARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDASLELFKFTIGMGEL------AFQ 613 K + E++ + ++ + LF G+ L A Sbjct: 539 FYYEETKG--------LSCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQH 590 Query: 614 EQLRFRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNHVADNSWSIWKLQKA 665 E F G + Y +++ V+LLNMLIA+M+ + +AD++ WK + Sbjct: 591 EFTEFVGATMFG--TYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFART 640 >6FES-A nrPDB Length = 367 Score = 40.0 bits (92), Expect = 0.004, Method: Compositional matrix adjust. Identities = 33/102 (32%), Positives = 47/102 (46%), Gaps = 18/102 (17%) Query: 154 NAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELP 213 + DE G + LH+A + L V++L++NGADV+ G P Sbjct: 31 DVNTADE--TGFTPLHLAAWEGHLGIVEVLLKNGADVN-------------ANDERGHTP 75 Query: 214 LSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVM 255 L LAA T ++V LL+N A + ATD +G LH M Sbjct: 76 LHLAAYTGHLEIVEVLLKN---GAGVNATDVIGTAPLHLAAM 114 Score = 37.0 bits (84), Expect = 0.031, Method: Compositional matrix adjust. Identities = 29/95 (30%), Positives = 42/95 (44%), Gaps = 18/95 (18%) Query: 154 NAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELP 213 + DE +GH+ LH+A L+ V++L++NGA V+ G P Sbjct: 64 DVNANDE--RGHTPLHLAAYTGHLEIVEVLLKNGAGVN-------------ATDVIGTAP 108 Query: 214 LSLAACTKQWDVVTYLLENPHQPASLEATDSLGNT 248 L LAA ++V LL+N A A D G T Sbjct: 109 LHLAAMWGHEEIVEVLLKN---GADARAQDKFGKT 140 >6AUN-A nrPDB Length = 752 Score = 39.7 bits (91), Expect = 0.004, Method: Compositional matrix adjust. Identities = 35/106 (33%), Positives = 48/106 (45%), Gaps = 17/106 (16%) Query: 210 GELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIH 269 G PL LA +++ L++ H A ++ TD+ G T H V DNS L + Sbjct: 152 GCTPLHLACRKGDSEILVELVQYCH--AQMDVTDNKGETAFHYAVQ-GDNSQVLQLLGKN 208 Query: 270 MYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHIL 315 GL Q+ N QGLTPL LA + GK E+ R +L Sbjct: 209 ASAGLNQV--------------NKQGLTPLHLACQMGKQEMVRVLL 240 Score = 32.3 bits (72), Expect = 0.74, Method: Compositional matrix adjust. Identities = 24/80 (30%), Positives = 39/80 (48%), Gaps = 16/80 (20%) Query: 112 TEGSTGKTCLMKAVL-NLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHI 170 + + G T L AV+ N D C+M LL ++G P G++ LH+ Sbjct: 312 STSAAGNTALHVAVMRNRFD----CVMVLLTYGANAGTPG-----------EHGNTPLHL 356 Query: 171 AIEKRSLQCVKLLVENGADV 190 AI K +++ +K L+ GA+V Sbjct: 357 AISKDNMEMIKALIVFGAEV 376 >5H76-A nrPDB Length = 201 Score = 39.7 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 40/137 (29%), Positives = 63/137 (45%), Gaps = 32/137 (23%) Query: 180 VKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASL 239 V++L+ NGADV+ + GT PL LAA + ++V LL++ A + Sbjct: 22 VRILMANGADVNA-------ADNTGTT------PLHLAAYSGHLEIVEVLLKHG---ADV 65 Query: 240 EATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPL 299 +A+D G T LH + + + LL+ GA + + G+TPL Sbjct: 66 DASDVFGYTPLHLAAYWGH---------LEIVEVLLKNGADV-------NAMDSDGMTPL 109 Query: 300 KLAAKEGKIEIFRHILQ 316 LAAK G +EI +L+ Sbjct: 110 HLAAKWGYLEIVEVLLK 126 Score = 38.1 bits (87), Expect = 0.014, Method: Composition-based stats. Identities = 30/88 (34%), Positives = 42/88 (47%), Gaps = 16/88 (18%) Query: 164 GHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQW 223 G + LH+A L+ V++L+++GADV FG PL LAA Sbjct: 39 GTTPLHLAAYSGHLEIVEVLLKHGADVDASDV-------------FGYTPLHLAAYWGHL 85 Query: 224 DVVTYLLENPHQPASLEATDSLGNTVLH 251 ++V LL+N A + A DS G T LH Sbjct: 86 EIVEVLLKN---GADVNAMDSDGMTPLH 110 Score = 35.8 bits (81), Expect = 0.070, Method: Composition-based stats. Identities = 32/111 (28%), Positives = 52/111 (46%), Gaps = 20/111 (18%) Query: 164 GHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQW 223 G++ LH+A L+ V++L++NGADV+ G PL LAA Sbjct: 72 GYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSD-------------GMTPLHLAAKWGYL 118 Query: 224 DVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGL 274 ++V LL++ ++ A D G T A + DN E+ A ++ Y+ L Sbjct: 119 EIVEVLLKH----GAVNAQDKFGKT---AFDISIDNGNEDLAQILAFYEIL 162 >5AQ9-A nrPDB Length = 422 Score = 39.3 bits (90), Expect = 0.007, Method: Compositional matrix adjust. Identities = 39/137 (28%), Positives = 58/137 (42%), Gaps = 32/137 (23%) Query: 180 VKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASL 239 V++L+ NGADV+ G PL LAA + ++V LL+ A + Sbjct: 30 VRILMANGADVN-------------AADNTGTTPLHLAAYSGHLEIVEVLLK---HGADV 73 Query: 240 EATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPL 299 +A+D G T LH + Y G L++ L + G+TPL Sbjct: 74 DASDVFGYTPLH----------------LAAYWGHLEIVEVLLKNGADVNAMDSDGMTPL 117 Query: 300 KLAAKEGKIEIFRHILQ 316 LAAK G +EI +L+ Sbjct: 118 HLAAKWGYLEIVEVLLK 134 Score = 38.1 bits (87), Expect = 0.016, Method: Compositional matrix adjust. Identities = 30/88 (34%), Positives = 42/88 (47%), Gaps = 16/88 (18%) Query: 164 GHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQW 223 G + LH+A L+ V++L+++GADV FG PL LAA Sbjct: 47 GTTPLHLAAYSGHLEIVEVLLKHGADVD-------------ASDVFGYTPLHLAAYWGHL 93 Query: 224 DVVTYLLENPHQPASLEATDSLGNTVLH 251 ++V LL+N A + A DS G T LH Sbjct: 94 EIVEVLLKN---GADVNAMDSDGMTPLH 118 Score = 35.4 bits (80), Expect = 0.099, Method: Compositional matrix adjust. Identities = 34/129 (26%), Positives = 57/129 (44%), Gaps = 21/129 (16%) Query: 153 VNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGEL 212 + +D F G++ LH+A L+ V++L++NGADV+ G Sbjct: 71 ADVDASDVF--GYTPLHLAAYWGHLEIVEVLLKNGADVN-------------AMDSDGMT 115 Query: 213 PLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYD 272 PL LAA ++V LL+ A + A D G T + DN ++ ++ + Sbjct: 116 PLHLAAKWGYLEIVEVLLK---HGADVNAQDKFGKTPFD---LADDNGNDDVGTLLQVAA 169 Query: 273 GLLQMGARL 281 Q+GAR+ Sbjct: 170 AADQLGARV 178 >6BPQ-A nrPDB Length = 950 Score = 38.9 bits (89), Expect = 0.009, Method: Compositional matrix adjust. Identities = 23/63 (36%), Positives = 36/63 (57%), Gaps = 1/63 (1%) Query: 609 ELAFQEQLRF-RGVVLLLLLAYVLLTYVLLLNMLIALMSETVNHVADNSWSIWKLQKAIS 667 EL Q RF + + L+ Y+L T +LL+N+L+A+ TV V +N+ +WK Q+ Sbjct: 816 ELDANNQPRFPEWITIPLVCIYMLSTNILLVNLLVAMFGYTVGSVQENNDQVWKFQRFFL 875 Query: 668 VLE 670 V E Sbjct: 876 VQE 878 >4OT9-A nrPDB Length = 359 Score = 38.5 bits (88), Expect = 0.010, Method: Compositional matrix adjust. Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 12/97 (12%) Query: 208 YFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALV 267 + + PL LA T Q VV++LL PA L D G++ +H + +PE Sbjct: 119 HLHQTPLHLAVITGQTSVVSFLLRVGADPALL---DRHGDSAMHLALRAGAGAPE----- 170 Query: 268 IHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAK 304 + LLQ GA P QL + + +GL P+ LA + Sbjct: 171 --LLRALLQSGAPAVP--QLLHMPDFEGLYPVHLAVR 203 Score = 35.8 bits (81), Expect = 0.068, Method: Compositional matrix adjust. Identities = 27/90 (30%), Positives = 45/90 (50%), Gaps = 14/90 (15%) Query: 162 YQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTK 221 ++G +H+A+ RS +C+ LLV++GA+V + T G L LA + Sbjct: 192 FEGLYPVHLAVRARSPECLDLLVDSGAEV------------EATERQGGRTALHLATEME 239 Query: 222 QWDVVTYLLENPHQPASLEATDSLGNTVLH 251 + +VT+L+ A++ A GNT LH Sbjct: 240 ELGLVTHLVTKLR--ANVNARTFAGNTPLH 267 >5AQA-A nrPDB Length = 418 Score = 38.1 bits (87), Expect = 0.015, Method: Compositional matrix adjust. Identities = 30/88 (34%), Positives = 42/88 (47%), Gaps = 16/88 (18%) Query: 164 GHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQW 223 G + LH+A L+ V++L+++GADV FG PL LAA Sbjct: 47 GTTPLHLAAYSGHLEIVEVLLKHGADVD-------------ASDVFGYTPLHLAAYWGHL 93 Query: 224 DVVTYLLENPHQPASLEATDSLGNTVLH 251 ++V LL+N A + A DS G T LH Sbjct: 94 EIVEVLLKN---GADVNAMDSDGMTPLH 118 Score = 37.7 bits (86), Expect = 0.020, Method: Compositional matrix adjust. Identities = 39/137 (28%), Positives = 58/137 (42%), Gaps = 32/137 (23%) Query: 180 VKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASL 239 V++L+ NGADV+ G PL LAA + ++V LL++ A + Sbjct: 30 VRILMANGADVN-------------AADNTGTTPLHLAAYSGHLEIVEVLLKHG---ADV 73 Query: 240 EATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPL 299 +A+D G T LH + Y G L++ L + G+TPL Sbjct: 74 DASDVFGYTPLH----------------LAAYWGHLEIVEVLLKNGADVNAMDSDGMTPL 117 Query: 300 KLAAKEGKIEIFRHILQ 316 LAAK G EI +L+ Sbjct: 118 HLAAKWGYKEIVEVLLK 134 Score = 29.3 bits (64), Expect = 7.1, Method: Compositional matrix adjust. Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 18/94 (19%) Query: 153 VNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGEL 212 + +D F G++ LH+A L+ V++L++NGADV+ G Sbjct: 71 ADVDASDVF--GYTPLHLAAYWGHLEIVEVLLKNGADVN-------------AMDSDGMT 115 Query: 213 PLSLAACTKQWDVVTYLLENPHQPASLEATDSLG 246 PL LAA ++V LL+ A ++A D G Sbjct: 116 PLHLAAKWGYKEIVEVLLK---AGADVDAQDKFG 146 >5AQB-A nrPDB Length = 428 Score = 37.4 bits (85), Expect = 0.023, Method: Compositional matrix adjust. Identities = 39/136 (28%), Positives = 60/136 (44%), Gaps = 30/136 (22%) Query: 153 VNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGEL 212 VNA D G++ LH+A L+ V++L++ GADV+ F Sbjct: 72 VNAADID----GYTPLHLAAFSGHLEIVEVLLKYGADVNADDQAGF-------------T 114 Query: 213 PLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPEN-------SA 265 PL LAA ++V LL+N A + A D G T + DN E+ +A Sbjct: 115 PLHLAAIFGHLEIVEVLLKN---GADVNAQDKFGKTPRDLAI---DNGNEDIAEVLGKAA 168 Query: 266 LVIHMYDGLLQMGARL 281 ++ + D Q+GAR+ Sbjct: 169 TLVKVKDAADQLGARV 184 >5MIO-C nrPDB Length = 573 Score = 37.0 bits (84), Expect = 0.034, Method: Compositional matrix adjust. Identities = 42/156 (26%), Positives = 67/156 (42%), Gaps = 35/156 (22%) Query: 180 VKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASL 239 V++L+ NGADV+ G PL LAA ++V LL++ A + Sbjct: 426 VRVLMANGADVNATDAS-------------GLTPLHLAATYGHLEIVEVLLKHG---ADV 469 Query: 240 EATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPL 299 A+D +G+T LH +I + + + LL+ GA + + G TPL Sbjct: 470 SASDLMGSTPLHLAALIGH---------LEIVEVLLKHGADVNAV-------DTWGDTPL 513 Query: 300 KLAAKEGKIEIFRHILQREFSGPYQPLSRKFTEWCY 335 +LAA G ++I +L+ G KF + Y Sbjct: 514 RLAAVMGHLKIVEALLKH---GADVNAQDKFGKTAY 546 Score = 31.6 bits (70), Expect = 1.4, Method: Compositional matrix adjust. Identities = 29/93 (31%), Positives = 44/93 (47%), Gaps = 17/93 (18%) Query: 164 GHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQW 223 G + LH+A L+ V++L+++GADV G PL LAA Sbjct: 443 GLTPLHLAATYGHLEIVEVLLKHGADV-------------SASDLMGSTPLHLAALIGHL 489 Query: 224 DVVTYLLENPHQPASLEATDSLGNTVLH-ALVM 255 ++V LL++ A + A D+ G+T L A VM Sbjct: 490 EIVEVLLKH---GADVNAVDTWGDTPLRLAAVM 519 >6MWQ-A nrPDB Length = 493 Score = 36.2 bits (82), Expect = 0.053, Method: Compositional matrix adjust. Identities = 27/88 (30%), Positives = 44/88 (50%), Gaps = 16/88 (18%) Query: 164 GHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQW 223 G + LH+A ++ L+ V++L++ GADV+ +G+ PL LAA Sbjct: 38 GLTPLHLAAQRGHLEIVEVLLKCGADVN-------------AADLWGQTPLHLAATAGHL 84 Query: 224 DVVTYLLENPHQPASLEATDSLGNTVLH 251 ++V LL+ A + A D +G T LH Sbjct: 85 EIVEVLLK---YGADVNALDLIGKTPLH 109 Score = 32.3 bits (72), Expect = 0.81, Method: Compositional matrix adjust. Identities = 43/137 (31%), Positives = 62/137 (45%), Gaps = 32/137 (23%) Query: 180 VKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASL 239 V++L+ NGADV+ A RF G PL LAA ++V LL+ A + Sbjct: 21 VRILMANGADVN--ALDRF-----------GLTPLHLAAQRGHLEIVEVLLKCG---ADV 64 Query: 240 EATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPL 299 A D G T LH +A + + + LL+ GA + L+ I G TPL Sbjct: 65 NAADLWGQTPLHLAA---------TAGHLEIVEVLLKYGADVNA---LDLI----GKTPL 108 Query: 300 KLAAKEGKIEIFRHILQ 316 L A +G +EI +L+ Sbjct: 109 HLTAIDGHLEIVEVLLK 125 >5GP7-A nrPDB Length = 169 Score = 35.8 bits (81), Expect = 0.079, Method: Composition-based stats. Identities = 38/152 (25%), Positives = 57/152 (37%), Gaps = 32/152 (21%) Query: 154 NAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELP 213 N C D + + LH+A +L+ + L+E+GADV+ + G G +P Sbjct: 33 NINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKG-------------GLIP 79 Query: 214 LSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDG 273 L AA D+ L++ + ATD T LH G Sbjct: 80 LHNAASYGHVDIAALLIK---YNTCVNATDKWAFTPLHEAAQ----------------KG 120 Query: 274 LLQMGARLCPTVQLEEISNHQGLTPLKLAAKE 305 Q+ A L + N +G TPL LA + Sbjct: 121 RTQLCALLLAHGADPTMKNQEGQTPLDLATAD 152 >5HKP-A nrPDB Length = 351 Score = 34.3 bits (77), Expect = 0.22, Method: Compositional matrix adjust. Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 10/96 (10%) Query: 139 LLQIDKDSGNPKLL-----VNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLR 193 LL+ + KL+ +N C + + LH+A ++ V+LL+++GADVH + Sbjct: 28 LLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAK 87 Query: 194 ACGRFFQKHQGTCFY----FGELPLSLAACTKQWDV 225 G H C Y EL L AC D+ Sbjct: 88 DKGGLVPLHNA-CSYGHYEVTELLLKHGACVNAMDL 122 >6CUD-A nrPDB Length = 806 Score = 34.3 bits (77), Expect = 0.23, Method: Compositional matrix adjust. Identities = 40/212 (18%), Positives = 88/212 (41%), Gaps = 34/212 (16%) Query: 467 FMDSYFEILFLLQALLTVLSQVLRFMETEWYLP---------LLVLSLVLGWLNLLYYTR 517 ++DSY + L + L Q + +W LP L +++VL + + Y Sbjct: 488 YVDSYVQESDLSEVTLPPEIQYFTYARDKW-LPSDPQIISEGLYAIAVVLSFSRIAYILP 546 Query: 518 GFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVSLSREARSPKAPEDNNSTVTE 577 + G + + + + +D+ +F++++++ F F + + L K Sbjct: 547 ANESFGPLQISLGRTV-KDIFKFMVLFIMVFFAFMIGMFILYSYYLGAKVN--------- 596 Query: 578 QPTVGQEEEPAPYRSILDASLELFKFTIGMGELA---FQEQLRF-RGVVLLLLLAYVLLT 633 A + ++ ++ LF G+ E+ + +F + +L Y + Sbjct: 597 ----------AAFTTVEESFKTLFWSIFGLSEVTSVVLKYDHKFIENIGYVLYGIYNVTM 646 Query: 634 YVLLLNMLIALMSETVNHVADNSWSIWKLQKA 665 V+LLNMLIA+++ + + D+S WK ++ Sbjct: 647 VVVLLNMLIAMINSSYQEIEDDSDVEWKFARS 678 >5JHQ-A nrPDB Length = 482 Score = 33.9 bits (76), Expect = 0.24, Method: Compositional matrix adjust. Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 10/96 (10%) Query: 139 LLQIDKDSGNPKLL-----VNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLR 193 LL+ + KL+ +N C + + LH+A ++ V+LL+++GADVH + Sbjct: 172 LLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAK 231 Query: 194 ACGRFFQKHQGTCFY----FGELPLSLAACTKQWDV 225 G H C Y EL L AC D+ Sbjct: 232 DKGGLVPLHN-ACSYGHYEVTELLLKHGACVNAMDL 266 Score = 29.6 bits (65), Expect = 4.6, Method: Compositional matrix adjust. Identities = 49/196 (25%), Positives = 72/196 (36%), Gaps = 40/196 (20%) Query: 153 VNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGEL 212 N D + S LH A V+ L++ GA+VH R G H F E+ Sbjct: 38 ANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEV 97 Query: 213 --------------------PLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHA 252 PL AA + DV LL++ P ++ NT + Sbjct: 98 VSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADP-------NIRNTDGKS 150 Query: 253 LVMIADNSPENSALVIHMY--DGLLQMG---------ARLCPTVQLEEISNHQGLTPLKL 301 + +AD P A++ Y D LL+ A L P S+ + TPL L Sbjct: 151 ALDLAD--PSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHL 208 Query: 302 AAKEGKIEIFRHILQR 317 AA ++ I + +LQ Sbjct: 209 AAGYNRVRIVQLLLQH 224 >4O1O-A nrPDB Length = 717 Score = 33.9 bits (76), Expect = 0.25, Method: Compositional matrix adjust. Identities = 46/170 (27%), Positives = 76/170 (44%), Gaps = 20/170 (11%) Query: 151 LLVNAQCTDEF-YQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYF 209 LL N + +E G +A A ++ ++ L ENGADV++ R ++ Q Sbjct: 94 LLPNVEDVNECDVNGFTAFMEAAVYGRVEALRFLYENGADVNMH---RKTKQDQERIRKG 150 Query: 210 GELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLG-NTVLHALVMIADNSPENSALVI 268 G L AA VVT LL A ++A D++G N +++AL+ N + A I Sbjct: 151 GATALMDAAEKGHVGVVTILLHA--MKAEVDARDNMGRNALVYALL----NPDDGKAKAI 204 Query: 269 HMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQRE 318 LL GA + + TPL LA + +++ + +L++E Sbjct: 205 TRL--LLDHGADV-------NVRGEGSKTPLILAVERKNLDLVQMLLEQE 245 >6CV9-A nrPDB Length = 842 Score = 33.5 bits (75), Expect = 0.37, Method: Compositional matrix adjust. Identities = 29/170 (17%), Positives = 75/170 (44%), Gaps = 24/170 (14%) Query: 500 LLVLSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVSLS 559 L +++VL + + Y + G + + + + +D+ +F++++++ F + + +L Sbjct: 509 LYAIAVVLSFSRIAYILPANESFGPLQISLGRTV-KDIFKFMVIFIMVFVAFMIGMFNLY 567 Query: 560 REARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDASLELFKFTIGMGEL---AFQEQL 616 +G ++ A + ++ ++ LF G+ E+ Sbjct: 568 ------------------SYYIGAKQNEA-FTTVEESFKTLFWAIFGLSEVKSVVINYNH 608 Query: 617 RF-RGVVLLLLLAYVLLTYVLLLNMLIALMSETVNHVADNSWSIWKLQKA 665 +F + +L Y + ++LLNMLIA+++ + + D++ WK +A Sbjct: 609 KFIENIGYVLYGVYNVTMVIVLLNMLIAMINSSFQEIEDDADVEWKFARA 658 >5CBO-A nrPDB Length = 176 Score = 32.3 bits (72), Expect = 0.77, Method: Composition-based stats. Identities = 24/72 (33%), Positives = 36/72 (50%), Gaps = 16/72 (22%) Query: 180 VKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASL 239 V++L+ NGADV+ FG PL LAA +++V LL+ A + Sbjct: 19 VRILMANGADVNAMD-------------NFGVTPLHLAAYWGHFEIVEVLLK---YGADV 62 Query: 240 EATDSLGNTVLH 251 A+D+ G+T LH Sbjct: 63 NASDATGDTPLH 74 >1WG0-A nrPDB Length = 243 Score = 30.8 bits (68), Expect = 2.4, Method: Compositional matrix adjust. Identities = 12/31 (38%), Positives = 21/31 (67%) Query: 163 QGHSALHIAIEKRSLQCVKLLVENGADVHLR 193 QG + LH+A+ K+ + + L+ENGA V ++ Sbjct: 106 QGVTCLHLAVGKKWFEVSQFLIENGASVRIK 136 >5Z1F-A nrPDB Length = 724 Score = 30.8 bits (68), Expect = 2.6, Method: Compositional matrix adjust. Identities = 15/50 (30%), Positives = 26/50 (52%) Query: 475 LFLLQALLTVLSQVLRFMETEWYLPLLVLSLVLGWLNLLYYTRGFQHTGI 524 LFL Q ++ F T +PL++ SL+ G++ + GF+HT + Sbjct: 624 LFLFQVVMFGYLGAKTFFYTALVIPLIITSLIFGYVCRQKFYGGFEHTAL 673 >1BD8-A nrPDB Length = 156 Score = 29.6 bits (65), Expect = 5.2, Method: Composition-based stats. Identities = 45/152 (29%), Positives = 61/152 (40%), Gaps = 35/152 (23%) Query: 78 DRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIM 137 DRL +RG +E+ LL + L GKT L + G A + Sbjct: 4 DRLSGAAARGDVQEVRRLLHRELVHPDALN-------RFGKTALQVMMF----GSTAIAL 52 Query: 138 PLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGR 197 LL K +P N Q T G S +H A L +K+LVE+GADV++ Sbjct: 53 ELL---KQGASP----NVQDT----SGTSPVHDAARTGFLDTLKVLVEHGADVNVP---- 97 Query: 198 FFQKHQGTCFYFGELPLSLAACTKQWDVVTYL 229 GT G LP+ LA VV++L Sbjct: 98 -----DGT----GALPIHLAVQEGHTAVVSFL 120 >6BWI-A nrPDB Length = 977 Score = 29.6 bits (65), Expect = 5.2, Method: Compositional matrix adjust. Identities = 14/30 (46%), Positives = 19/30 (63%) Query: 635 VLLLNMLIALMSETVNHVADNSWSIWKLQK 664 +LL+N+LIA+ S T V NS WK Q+ Sbjct: 834 ILLVNLLIAMFSYTFGKVQGNSDLYWKAQR 863 >6EMK-G nrPDB Length = 426 Score = 29.3 bits (64), Expect = 5.9, Method: Compositional matrix adjust. Identities = 28/122 (22%), Positives = 48/122 (39%), Gaps = 29/122 (23%) Query: 117 GKTCLMKAVLNLQDGVNACIMPLLQ-----IDKDSGNPKLLVNAQCTDEFYQ-------- 163 G TC+ L L G + LLQ I+ N + ++ C +++YQ Sbjct: 75 GNTCVH---LALMKGHEQTLHLLLQQFPRFINHRGENGRAPIHIACMNDYYQCLSLLIGV 131 Query: 164 ----------GHSALHIAIEKRSLQCVKLLVENGA---DVHLRACGRFFQKHQGTCFYFG 210 G + LH+ +E S+ C+K+L+ G D ++R G + F G Sbjct: 132 GADLWVMDTNGDTPLHVCLEYGSISCMKMLLNEGEVSLDDNVRDKGNWKPIDVAQTFEVG 191 Query: 211 EL 212 + Sbjct: 192 NI 193 >5ET1-A nrPDB Length = 353 Score = 29.3 bits (64), Expect = 7.5, Method: Compositional matrix adjust. Identities = 11/29 (37%), Positives = 20/29 (68%) Query: 295 GLTPLKLAAKEGKIEIFRHILQREFSGPY 323 G TPL LA +EG +E+ ++++Q + P+ Sbjct: 173 GATPLYLACQEGHLEVTKYLVQECSADPH 201 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5HI9-A nrPDB 1242 0.0 6OO7-A nrPDB 1092 0.0 6BO5-A nrPDB 1053 0.0 6BBJ-A nrPDB 932 0.0 6C8G-A nrPDB 890 0.0 5IRX-A nrPDB 886 0.0 5AN8-A nrPDB 884 0.0 6DVZ-A nrPDB 841 0.0 6MHW-A nrPDB 815 0.0 6E2G-A nrPDB 689 0.0 6BOA-A nrPDB 684 0.0 6DMR-A nrPDB 658 0.0 2ETB-A nrPDB 414 e-116 2F37-A nrPDB 402 e-112 4DX2-A nrPDB 372 e-103 3W9G-A nrPDB 372 e-103 2NYJ-A nrPDB 366 e-101 4N5Q-A nrPDB 317 1e-86 2RFA-A nrPDB 250 2e-66 6G1K-A nrPDB 223 2e-58 5AQ7-A nrPDB 140 2e-33 Sequences not found previously or not previously below threshold: 5Z96-A nrPDB 208 7e-54 6FES-A nrPDB 120 2e-27 5AQA-A nrPDB 119 5e-27 5AQ9-A nrPDB 105 6e-23 5H76-A nrPDB 97 2e-20 6MWQ-A nrPDB 96 8e-20 5AQB-A nrPDB 91 1e-18 6CUD-A nrPDB 89 6e-18 5MIO-C nrPDB 85 1e-16 6CV9-A nrPDB 84 2e-16 5CBO-A nrPDB 77 3e-14 4OAU-C nrPDB 72 8e-13 6BWF-A nrPDB 68 1e-11 5GP7-A nrPDB 67 4e-11 6BPQ-A nrPDB 65 1e-10 5JHQ-A nrPDB 62 8e-10 2DWZ-A nrPDB 62 1e-09 4NIK-A nrPDB 61 1e-09 5HKP-A nrPDB 61 2e-09 4Z68-A nrPDB 61 3e-09 6AUN-A nrPDB 59 8e-09 5ET1-A nrPDB 58 2e-08 3B7B-A nrPDB 57 3e-08 1BD8-A nrPDB 53 4e-07 4OT9-A nrPDB 53 6e-07 6BY9-A nrPDB 52 9e-07 1BLX-B nrPDB 52 1e-06 1WG0-A nrPDB 50 4e-06 3UI2-A nrPDB 49 1e-05 3DEO-A nrPDB 49 1e-05 4O1O-A nrPDB 47 3e-05 1G3N-B nrPDB 45 8e-05 5DND-A nrPDB 45 9e-05 3ZKJ-A nrPDB 45 9e-05 3EU9-A nrPDB 45 2e-04 3T9K-A nrPDB 43 6e-04 6EMK-G nrPDB 42 8e-04 3EHQ-A nrPDB 42 9e-04 4BSZ-B nrPDB 42 0.001 5U0K-A nrPDB 40 0.004 2KXP-C nrPDB 39 0.005 5D68-A nrPDB 39 0.006 6BWI-A nrPDB 39 0.007 5Z1W-A nrPDB 37 0.022 5T4D-A nrPDB 37 0.025 6DU8-A nrPDB 37 0.035 5MKE-A nrPDB 37 0.044 5UQE-A nrPDB 36 0.061 5U0J-A nrPDB 36 0.061 5WPT-A nrPDB 35 0.15 6E7Z-A nrPDB 34 0.21 6D1W-A nrPDB 34 0.24 6AYG-A nrPDB 34 0.24 3LJN-A nrPDB 34 0.35 3LVQ-E nrPDB 33 0.49 2B0O-E nrPDB 33 0.49 1D9S-A nrPDB 33 0.57 6ACN-A nrPDB 32 0.90 1DCQ-A nrPDB 32 1.0 2QSG-A nrPDB 31 2.1 6DJS-A nrPDB 30 3.3 4P5Q-A nrPDB 30 3.4 6N4I-A nrPDB 30 5.0 4E68-A nrPDB 29 9.3 >5HI9-A nrPDB Length = 770 Score = 1242 bits (3213), Expect = 0.0, Method: Composition-based stats. Identities = 760/761 (99%), Positives = 760/761 (99%) Query: 1 MTSASSPPAFRLETSDGDEEGNAEVNKGKQEPPPMESPFQREDRNSSPQIKVNLNFIKRP 60 MTSASSPPAFRLETSDGDEEGNAEVNKGKQEPPPMESPFQREDRNSSPQIKVNLNFIKRP Sbjct: 1 MTSASSPPAFRLETSDGDEEGNAEVNKGKQEPPPMESPFQREDRNSSPQIKVNLNFIKRP 60 Query: 61 PKNTSAPSQQEPDRFDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTC 120 PKNTSAPSQQEPDRFDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTC Sbjct: 61 PKNTSAPSQQEPDRFDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTC 120 Query: 121 LMKAVLNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCV 180 LMKAVLNLQDGVNACIMPLLQIDKDSGNPK LVNAQCTDEFYQGHSALHIAIEKRSLQCV Sbjct: 121 LMKAVLNLQDGVNACIMPLLQIDKDSGNPKPLVNAQCTDEFYQGHSALHIAIEKRSLQCV 180 Query: 181 KLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLE 240 KLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLE Sbjct: 181 KLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLE 240 Query: 241 ATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLK 300 ATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLK Sbjct: 241 ATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLK 300 Query: 301 LAAKEGKIEIFRHILQREFSGPYQPLSRKFTEWCYGPVRVSLYDLSSVDSWEKNSVLEII 360 LAAKEGKIEIFRHILQREFSGPYQPLSRKFTEWCYGPVRVSLYDLSSVDSWEKNSVLEII Sbjct: 301 LAAKEGKIEIFRHILQREFSGPYQPLSRKFTEWCYGPVRVSLYDLSSVDSWEKNSVLEII 360 Query: 361 AFHCKSPNRHRMVVLEPLNKLLQEKWDRLVSRFFFNFACYLVYMFIFTVVAYHQPSLDQP 420 AFHCKSPNRHRMVVLEPLNKLLQEKWDRLVSRFFFNFACYLVYMFIFTVVAYHQPSLDQP Sbjct: 361 AFHCKSPNRHRMVVLEPLNKLLQEKWDRLVSRFFFNFACYLVYMFIFTVVAYHQPSLDQP 420 Query: 421 AIPSSKATFGESMLLLGHILILLGGIYLLLGQLWYFWRRRLFIWISFMDSYFEILFLLQA 480 AIPSSKATFGESMLLLGHILILLGGIYLLLGQLWYFWRRRLFIWISFMDSYFEILFLLQA Sbjct: 421 AIPSSKATFGESMLLLGHILILLGGIYLLLGQLWYFWRRRLFIWISFMDSYFEILFLLQA 480 Query: 481 LLTVLSQVLRFMETEWYLPLLVLSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRF 540 LLTVLSQVLRFMETEWYLPLLVLSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRF Sbjct: 481 LLTVLSQVLRFMETEWYLPLLVLSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRF 540 Query: 541 LLVYLVFLFGFAVALVSLSREARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDASLEL 600 LLVYLVFLFGFAVALVSLSREARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDASLEL Sbjct: 541 LLVYLVFLFGFAVALVSLSREARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDASLEL 600 Query: 601 FKFTIGMGELAFQEQLRFRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNHVADNSWSIW 660 FKFTIGMGELAFQEQLRFRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNHVADNSWSIW Sbjct: 601 FKFTIGMGELAFQEQLRFRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNHVADNSWSIW 660 Query: 661 KLQKAISVLEMENGYWWCRRKKHREGRLLKVGTRGDGTPDERWCFRVEEVNWAAWEKTLP 720 KLQKAISVLEMENGYWWCRRKKHREGRLLKVGTRGDGTPDERWCFRVEEVNWAAWEKTLP Sbjct: 661 KLQKAISVLEMENGYWWCRRKKHREGRLLKVGTRGDGTPDERWCFRVEEVNWAAWEKTLP 720 Query: 721 TLSEDPSGPGITGNKKNPTSKPGKNSASEEDHLPLQVLQSP 761 TLSEDPSGPGITGNKKNPTSKPGKNSASEEDHLPLQVLQSP Sbjct: 721 TLSEDPSGPGITGNKKNPTSKPGKNSASEEDHLPLQVLQSP 761 >6OO7-A nrPDB Length = 786 Score = 1092 bits (2825), Expect = 0.0, Method: Composition-based stats. Identities = 615/767 (80%), Positives = 667/767 (86%), Gaps = 13/767 (1%) Query: 1 MTSASSPPAFRLETSDGDEEGNAEVNKGK----QEPPPMESPFQREDRNSSPQIKVNLNF 56 MTS SSPPAFRLETSDG ++G AEV+K + PPPMES FQ EDRN PQIKVNLN+ Sbjct: 1 MTSPSSPPAFRLETSDGGQDG-AEVDKAQLGYGAGPPPMESRFQDEDRNFPPQIKVNLNY 59 Query: 57 IKRPPKNTSAPSQQEPDRFDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGST 116 + + SQ + +RFDRDRLF+VV+RG PE+L GLLEYLR SKYLTDS YTEGST Sbjct: 60 -----RKGAGASQPDLNRFDRDRLFNVVARGNPEDLAGLLEYLRRTSKYLTDSEYTEGST 114 Query: 117 GKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRS 176 GKTCLMKAVLNLQDGVNACI PLL+ID+DSGNP+ LVNAQCTDE+Y+GHSALHIAIEKRS Sbjct: 115 GKTCLMKAVLNLQDGVNACIQPLLEIDRDSGNPQPLVNAQCTDEYYRGHSALHIAIEKRS 174 Query: 177 LQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQP 236 LQCVKLLVENGA+VH +ACG FFQK+Q TCFYFGELPLSLAACTKQWDVV YLLENPHQP Sbjct: 175 LQCVKLLVENGANVHAKACGHFFQKNQDTCFYFGELPLSLAACTKQWDVVNYLLENPHQP 234 Query: 237 ASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGL 296 ASL+A DSLGNTVLHALVMIAD+S ENSALV+ MYDGLLQ GARLCP VQLE I N +GL Sbjct: 235 ASLQAQDSLGNTVLHALVMIADDSAENSALVVRMYDGLLQAGARLCPNVQLEGIPNLEGL 294 Query: 297 TPLKLAAKEGKIEIFRHILQREFSGPYQPLSRKFTEWCYGPVRVSLYDLSSVDSWEKNSV 356 TPLKLAAKEGKIEIF+HILQREFS P Q LSRKFTEWCYGPVRVSLYDL+SVDSWE+NSV Sbjct: 295 TPLKLAAKEGKIEIFKHILQREFSAPCQSLSRKFTEWCYGPVRVSLYDLASVDSWEENSV 354 Query: 357 LEIIAFHCKSPNRHRMVVLEPLNKLLQEKWDRLVSRFFFNFACYLVYMFIFTVVAYHQPS 416 LEIIAFH +SP+RHRMVVLEPLNKLLQ KWDRL+ RF FNF CYLVYM IFT VAYHQP+ Sbjct: 355 LEIIAFHSRSPHRHRMVVLEPLNKLLQAKWDRLIPRFCFNFLCYLVYMLIFTAVAYHQPA 414 Query: 417 LDQPAIPSSKATFGESMLLLGHILILLGGIYLLLGQLWYFWRRRLFIWISFMDSYFEILF 476 L++ P KAT G SMLLLGHILILLGG+YLLLGQLWYFWRRRLFIWISFMDSY EILF Sbjct: 415 LEKQGFPPLKATAGNSMLLLGHILILLGGVYLLLGQLWYFWRRRLFIWISFMDSYSEILF 474 Query: 477 LLQALLTVLSQVLRFMETEWYLPLLVLSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRD 536 LLQALLTVLSQVL F+ EWYLPLLV SL +GW NLLYYTRGFQHTGIYSVMI+KVILRD Sbjct: 475 LLQALLTVLSQVLCFLAIEWYLPLLVSSLAMGWTNLLYYTRGFQHTGIYSVMIEKVILRD 534 Query: 537 LLRFLLVYLVFLFGFAVALVSLSREARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDA 596 LLRFLLVYLVFLFGFAVALVSLSREA++ + P N+T QP GQE+E PYRSILDA Sbjct: 535 LLRFLLVYLVFLFGFAVALVSLSREAQNSRTPAGPNATEVGQPGAGQEDEAPPYRSILDA 594 Query: 597 SLELFKFTIGMGELAFQEQLRFRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNHVADNS 656 SLELFKFTIGMGELAFQEQLRFRGVVLLLLLAYVLLTYVLLLNMLIALMSETVN VA +S Sbjct: 595 SLELFKFTIGMGELAFQEQLRFRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNSVATDS 654 Query: 657 WSIWKLQKAISVLEMENGYWWCRRKKHREGRLLKVGTRGDGTPDERWCFRVEEVNWAAWE 716 WSIWKLQKAISVLEMENGYWWCRRKK R G +L VGTR DG+PDERWCFRV E+NWA WE Sbjct: 655 WSIWKLQKAISVLEMENGYWWCRRKKQRAGVMLTVGTRPDGSPDERWCFRVGEMNWATWE 714 Query: 717 KTLP-TLSEDPSGPGITGNKKNPT--SKPGKNSASEEDHLPLQVLQS 760 +TLP TL E+PSG G KNPT S+ G++SASEEDHLPLQ+LQS Sbjct: 715 QTLPRTLCEEPSGAAAPGVMKNPTPASQRGEDSASEEDHLPLQLLQS 761 >6BO5-A nrPDB Length = 695 Score = 1053 bits (2724), Expect = 0.0, Method: Composition-based stats. Identities = 654/668 (97%), Positives = 656/668 (98%) Query: 60 PPKNTSAPSQQEPDRFDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKT 119 + PDRFDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKT Sbjct: 20 ENNGSLGFEAPTPDRFDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKT 79 Query: 120 CLMKAVLNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQC 179 CLMKAVLNLQDGVNACIMPLLQIDKDSGNPK LVNAQCTDEFYQGHSALHIAIEKRSLQC Sbjct: 80 CLMKAVLNLQDGVNACIMPLLQIDKDSGNPKPLVNAQCTDEFYQGHSALHIAIEKRSLQC 139 Query: 180 VKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASL 239 VKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASL Sbjct: 140 VKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASL 199 Query: 240 EATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPL 299 EATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPL Sbjct: 200 EATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPL 259 Query: 300 KLAAKEGKIEIFRHILQREFSGPYQPLSRKFTEWCYGPVRVSLYDLSSVDSWEKNSVLEI 359 KLAAKEGKIEIFRHILQREFSGPYQPLSRKFTEWCYGPVRVSLYDLSSVDSWEKNSVLEI Sbjct: 260 KLAAKEGKIEIFRHILQREFSGPYQPLSRKFTEWCYGPVRVSLYDLSSVDSWEKNSVLEI 319 Query: 360 IAFHCKSPNRHRMVVLEPLNKLLQEKWDRLVSRFFFNFACYLVYMFIFTVVAYHQPSLDQ 419 IAFHCKSPNRHRMVVLEPLNKLLQEKWDRLVSRFFFNFACYLVYMFIFTVVAYHQPSLDQ Sbjct: 320 IAFHCKSPNRHRMVVLEPLNKLLQEKWDRLVSRFFFNFACYLVYMFIFTVVAYHQPSLDQ 379 Query: 420 PAIPSSKATFGESMLLLGHILILLGGIYLLLGQLWYFWRRRLFIWISFMDSYFEILFLLQ 479 PAIPSSKATFGESMLLLGHILILLGGIYLLLGQLWYFWRRRLFIWISFMDSYFEILFLLQ Sbjct: 380 PAIPSSKATFGESMLLLGHILILLGGIYLLLGQLWYFWRRRLFIWISFMDSYFEILFLLQ 439 Query: 480 ALLTVLSQVLRFMETEWYLPLLVLSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLR 539 ALLTVLSQVLRFMETEWYLPLLVLSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLR Sbjct: 440 ALLTVLSQVLRFMETEWYLPLLVLSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLR 499 Query: 540 FLLVYLVFLFGFAVALVSLSREARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDASLE 599 FLLVYLVFLFGFAVALVSLSREARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDASLE Sbjct: 500 FLLVYLVFLFGFAVALVSLSREARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDASLE 559 Query: 600 LFKFTIGMGELAFQEQLRFRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNHVADNSWSI 659 LFKFTIGMGELAFQEQLRFRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNHVADNSWSI Sbjct: 560 LFKFTIGMGELAFQEQLRFRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNHVADNSWSI 619 Query: 660 WKLQKAISVLEMENGYWWCRRKKHREGRLLKVGTRGDGTPDERWCFRVEEVNWAAWEKTL 719 WKLQKAISVLEMENGYWWCRRKKHREGRLLKVGTRGDGTPDERWCFRVEEVNWAAWEKTL Sbjct: 620 WKLQKAISVLEMENGYWWCRRKKHREGRLLKVGTRGDGTPDERWCFRVEEVNWAAWEKTL 679 Query: 720 PTLSEDPS 727 PTLSEDP+ Sbjct: 680 PTLSEDPT 687 >6BBJ-A nrPDB Length = 868 Score = 932 bits (2408), Expect = 0.0, Method: Composition-based stats. Identities = 317/706 (44%), Positives = 443/706 (62%), Gaps = 21/706 (2%) Query: 34 PMESPFQREDRNSSP---QIKVNLNFIKRPPKNTSAPSQQEP---DRFDRDRLFSVVSRG 87 PM+S F E + P + K +++ N+ APS P F+R LF +VSRG Sbjct: 98 PMDSLFGYETYHHHPTENRRKRKKILLEKENLNSQAPSPDPPPVIKMFNRHMLFDIVSRG 157 Query: 88 VPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSG 147 EL G L +L K LTD + E STGKTCL KA++NL G N I L+ I + +G Sbjct: 158 STAELEGFLPFLLAQKKRLTDEEFREASTGKTCLTKALMNLNGGKNDTIPMLIDIAEKTG 217 Query: 148 NPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQ-KHQGTC 206 N + +N+ D +Y+G +ALHIAIE+R V+LLVE GADVH +A GRFFQ K +G Sbjct: 218 NLREFINSPFRDVYYRGQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGY 277 Query: 207 FYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSAL 266 FYFGELPLSLAACT Q D+V YL EN H+ A + DS GNTVLHALV IADN+ EN+ Sbjct: 278 FYFGELPLSLAACTNQPDIVHYLTENAHKKADIRRQDSRGNTVLHALVAIADNTRENTKF 337 Query: 267 VIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQREFS-GPYQP 325 V +YD L+ +L P LE I N+ ++PL +AAK GKI IF+HI++ E + Sbjct: 338 VTKVYDLLVIKCVKLYPDSSLEAIFNNDSMSPLMMAAKLGKIGIFQHIIRLEIKDEEARH 397 Query: 326 LSRKFTEWCYGPVRVSLYDLSSVDSW-EKNSVLEIIAFHCKSPNRHRMVVLEPLNKLLQE 384 LSRKF +W YGPV SLYDLS +D+ E+ SVLEI+ ++ K NRH M+ +EP+N+LL++ Sbjct: 398 LSRKFRDWAYGPVYSSLYDLSMLDTCGEEVSVLEILVYNSKVENRHEMLAVEPINELLRD 457 Query: 385 KWDRLV-SRFFFNFACYLVYMFIFTVVAYHQPSLDQPAIPSSKATFGESMLLLGHILILL 443 KW + F+ + YL+ M IFT++AY++P P P T + M L G I+ LL Sbjct: 458 KWQKFGAVSFYISVVSYLIAMIIFTLIAYYRPMDGTPPYPYR--TTMDYMRLAGEIVTLL 515 Query: 444 GGIYLLLGQLWY-FWRRRLFIWISFMDSYFEILFLLQALLTVLSQVLRFMETEWYLPLLV 502 G+ + + F ++ + F+D F++L+ + ++L +++ VL + E YL ++V Sbjct: 516 TGVVFFITNIKDLFMKKCPGVNSLFIDGSFQLLYFIYSVLVIITAVLYLVGIESYLAVMV 575 Query: 503 LSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVSLSREA 562 +LVLGW+N LY+TRG + TG YS+M+QK++ +DL RFLLVYL+F+ G+A ALVSL Sbjct: 576 FALVLGWMNALYFTRGLKLTGTYSIMLQKILFKDLFRFLLVYLLFMIGYASALVSLLNPC 635 Query: 563 RSPKA--PEDNNSTVTEQPTVGQEEEPAPYRSILDASLELFKFTIGMGELAFQEQLRFRG 620 S ++ +N TV E P+ + + + L L+LFK TIGMG+L ++ Sbjct: 636 TSQESCIETSSNCTVPEYPSC---RDSSTFSKFL---LDLFKLTIGMGDLEMINSAKYPA 689 Query: 621 VVLLLLLAYVLLTYVLLLNMLIALMSETVNHVADNSWSIWKLQKAISVLEMENGYWWCRR 680 V ++LL+ Y++LT+VLLLNMLIALM ETV V+ S IWKLQ A ++L++E + C R Sbjct: 690 VFIILLVTYIILTFVLLLNMLIALMGETVGQVSKESKQIWKLQWATTILDIERSFPVCMR 749 Query: 681 KKHREGRLLKVGTRGDGTPDERWCFRVEEVNWAAWEKTLPTLSEDP 726 K R G ++ VG DGTPD RWCFRV+EVNW+ W + L ++EDP Sbjct: 750 KAFRSGEMVTVGKNLDGTPDRRWCFRVDEVNWSHWNQNLGIINEDP 795 >6C8G-A nrPDB Length = 675 Score = 890 bits (2299), Expect = 0.0, Method: Composition-based stats. Identities = 308/671 (45%), Positives = 427/671 (63%), Gaps = 18/671 (2%) Query: 66 APSQQEP---DRFDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLM 122 APS P F+R LF +VSRG EL G L +L K LTD + E STGKTCL Sbjct: 2 APSPDPPPVIKMFNRHMLFDIVSRGSTAELEGFLPFLLAQKKRLTDEEFREASTGKTCLT 61 Query: 123 KAVLNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKL 182 KA++NL G N I L+ I + +GN + +N+ D +Y+G +ALHIAIE+R V+L Sbjct: 62 KALMNLNGGKNDTIPMLIDIAEKTGNLREFINSPFRDVYYRGQTALHIAIERRCKHYVEL 121 Query: 183 LVENGADVHLRACGRFFQ-KHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEA 241 LVE GADVH +A GRFFQ K +G FYFGELPLSLAACT Q D+V YL EN H+ A + Sbjct: 122 LVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPDIVHYLTENAHKKADIRR 181 Query: 242 TDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKL 301 DS GNTVLHALV IADN+ EN+ V +YD L+ +L P LE I N+ ++PL + Sbjct: 182 QDSRGNTVLHALVAIADNTRENTKFVTKVYDLLVIKCVKLYPDSSLEAIFNNDSMSPLMM 241 Query: 302 AAKEGKIEIFRHILQREFS-GPYQPLSRKFTEWCYGPVRVSLYDLSSVDSW-EKNSVLEI 359 AAK GKI IF+HI++ E + LSRKF +W YGPV SLYDLS +D+ E+ SVLEI Sbjct: 242 AAKLGKIGIFQHIIRLEIKDEEARHLSRKFRDWAYGPVYSSLYDLSMLDTCGEEVSVLEI 301 Query: 360 IAFHCKSPNRHRMVVLEPLNKLLQEKWDRLV-SRFFFNFACYLVYMFIFTVVAYHQPSLD 418 + ++ K NRH M+ +EP+N+LL++KW + F+ + YL+ M IFT++AY++P Sbjct: 302 LVYNSKVENRHEMLAVEPINELLRDKWQKFGAVSFYISVVSYLIAMIIFTLIAYYRPMDG 361 Query: 419 QPAIPSSKATFGESMLLLGHILILLGGIYLLLGQLWY-FWRRRLFIWISFMDSYFEILFL 477 P P T + M L G I+ LL G+ + + F ++ + F+D F++L+ Sbjct: 362 TPPYPYR--TTMDYMRLAGEIVTLLTGVVFFITNIKDLFMKKCPGVNSLFIDGSFQLLYF 419 Query: 478 LQALLTVLSQVLRFMETEWYLPLLVLSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDL 537 + ++L +++ VL + E YL ++V +LVLGW+N LY+TRG + TG YS+M+QK++ +DL Sbjct: 420 IYSVLVIITAVLYLVGIESYLAVMVFALVLGWMNALYFTRGLKLTGTYSIMLQKILFKDL 479 Query: 538 LRFLLVYLVFLFGFAVALVSLSREARSPKA--PEDNNSTVTEQPTVGQEEEPAPYRSILD 595 RFLLVYL+F+ G+A ALVSL S ++ + TV E P+ + + + L Sbjct: 480 FRFLLVYLLFMIGYASALVSLLNPCTSQESCIETSSQCTVPEYPSC---RDSSTFSKFL- 535 Query: 596 ASLELFKFTIGMGELAFQEQLRFRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNHVADN 655 L+LFK TIGMG+L ++ V ++LL+ Y++LT+VLLLNMLIALM ETV V+ Sbjct: 536 --LDLFKLTIGMGDLEMINSAKYPAVFIILLVTYIILTFVLLLNMLIALMGETVGQVSKE 593 Query: 656 SWSIWKLQKAISVLEMENGYWWCRRKKHREGRLLKVGTRGDGTPDERWCFRVEEVNWAAW 715 S IWKLQ A ++L++E + C RK R G ++ VG DGTPD RWCFRV+EVNW+ W Sbjct: 594 SKQIWKLQWATTILDIERSFPVCMRKAFRSGEMVTVGKNLDGTPDRRWCFRVDEVNWSHW 653 Query: 716 EKTLPTLSEDP 726 + L ++EDP Sbjct: 654 NQNLGIINEDP 664 >5IRX-A nrPDB Length = 636 Score = 886 bits (2288), Expect = 0.0, Method: Composition-based stats. Identities = 338/658 (51%), Positives = 443/658 (67%), Gaps = 31/658 (4%) Query: 73 DRFDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGV 132 +DR +F V++ +EL LL +L+ + K LTDS + + TGKTCL+KA+LNL +G Sbjct: 5 RLYDRRSIFDAVAQSNCQELESLLPFLQRSKKRLTDSEFKDPETGKTCLLKAMLNLHNGQ 64 Query: 133 NACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHL 192 N I LL + + + + K VNA TD +Y+G +ALHIAIE+R++ V LLVENGADV Sbjct: 65 NDTIALLLDVARKTDSLKQFVNASYTDSYYKGQTALHIAIERRNMTLVTLLVENGADVQA 124 Query: 193 RACGRFFQKHQGT-CFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLH 251 A G FF+K +G FYFGELPLSLAACT Q +V +LL+N QPA + A DS+GNTVLH Sbjct: 125 AANGDFFKKTKGRPGFYFGELPLSLAACTNQLAIVKFLLQNSWQPADISARDSVGNTVLH 184 Query: 252 ALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIF 311 ALV +ADN+ +N+ V MY+ +L +GA+L PT++LEEI+N +GLTPL LAA GKI + Sbjct: 185 ALVEVADNTVDNTKFVTSMYNEILILGAKLHPTLKLEEITNRKGLTPLALAASSGKIGVL 244 Query: 312 RHILQREFSGP-YQPLSRKFTEWCYGPVRVSLYDLSSVDSWEKNSVLEIIAFHC-KSPNR 369 +ILQRE P + LSRKFTEW YGPV SLYDLS +D+ EKNSVLE+IA+ ++PNR Sbjct: 245 AYILQREIHEPECRHLSRKFTEWAYGPVHSSLYDLSCIDTCEKNSVLEVIAYSSSETPNR 304 Query: 370 HRMVVLEPLNKLLQEKWDRLVSR-FFFNFACYLVYMFIFTVVAYHQPSLDQPAIPSSKAT 428 H M+++EPLN+LLQ+KWDR V R F+FNF Y +YM IFT AY++P P K T Sbjct: 305 HDMLLVEPLNRLLQDKWDRFVKRIFYFNFFVYCLYMIIFTAAAYYRPVEGLPPYK-LKNT 363 Query: 429 FGESMLLLGHILILLGGIYLLLGQLWYFWRRRLFIWISFMDSYFEILFLLQALLTVLSQV 488 G+ + G IL + GG+Y + YF +RR + F+DSY EILF +Q+L ++S V Sbjct: 364 VGDYFRVTGEILSVSGGVYFFFRGIQYFLQRRPSLKSLFVDSYSEILFFVQSLFMLVSVV 423 Query: 489 LRFMETEWYLPLLVLSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFL 548 L F + + Y+ +V SL +GW N+LYYTRGFQ GIY+VMI+K+ILRDL RF+ VYLVFL Sbjct: 424 LYFSQRKEYVASMVFSLAMGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYLVFL 483 Query: 549 FGFAVALVSLSREARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDASLELFKFTIGMG 608 FGF+ A+V+L E Y S+ LELFKFTIGMG Sbjct: 484 FGFSTAVVTLI--------------------------EDGKYNSLYSTCLELFKFTIGMG 517 Query: 609 ELAFQEQLRFRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNHVADNSWSIWKLQKAISV 668 +L F E F+ V ++LLLAYV+LTY+LLLNMLIALM ETVN +A S +IWKLQ+AI++ Sbjct: 518 DLEFTENYDFKAVFIILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAITI 577 Query: 669 LEMENGYWWCRRKKHREGRLLKVGTRGDGTPDERWCFRVEEVNWAAWEKTLPTLSEDP 726 L+ E + C RK R G+LL+VG DG D RWCFRV+EVNW W + ++EDP Sbjct: 578 LDTEKSFLKCMRKAFRSGKLLQVGFTPDGKDDYRWCFRVDEVNWTTWNTNVGIINEDP 635 >5AN8-A nrPDB Length = 613 Score = 884 bits (2283), Expect = 0.0, Method: Composition-based stats. Identities = 532/633 (84%), Positives = 562/633 (88%), Gaps = 20/633 (3%) Query: 78 DRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIM 137 DRLF+VV+RG PE+L GLLEYLR SKYLTDS YTEGSTGKTCLMKAVLNLQDGVNACI Sbjct: 1 DRLFNVVARGNPEDLAGLLEYLRRTSKYLTDSEYTEGSTGKTCLMKAVLNLQDGVNACIQ 60 Query: 138 PLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGR 197 PLL+ID+DSGNP+ LVNAQCTDE+Y+GHSALHIAIEKRSLQCVKLLVENGA+VH +ACG Sbjct: 61 PLLEIDRDSGNPQPLVNAQCTDEYYRGHSALHIAIEKRSLQCVKLLVENGANVHAKACGH 120 Query: 198 FFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIA 257 FFQK+Q TCFYFGELPLSLAACTKQWDVV YLLENPH ASL+A DSLGNTVLHALVMIA Sbjct: 121 FFQKNQDTCFYFGELPLSLAACTKQWDVVNYLLENPHPAASLQAQDSLGNTVLHALVMIA 180 Query: 258 DNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQR 317 DNSPENSALV+ MYDGLLQ GARLCP VQLE I N +GLTPLKLAAKEGKIEIF+HILQR Sbjct: 181 DNSPENSALVVRMYDGLLQAGARLCPNVQLEGIPNLEGLTPLKLAAKEGKIEIFKHILQR 240 Query: 318 EFSGPYQPLSRKFTEWCYGPVRVSLYDLSSVDSWEKNSVLEIIAFHCKSPNRHRMVVLEP 377 EFS P Q LSRKFTEWCYGPVRVSLYDL+SVDSWE+NSVLEIIAFH +SP+RHRMVVLEP Sbjct: 241 EFSAPCQSLSRKFTEWCYGPVRVSLYDLASVDSWEENSVLEIIAFHSRSPHRHRMVVLEP 300 Query: 378 LNKLLQEKWDRLVSRFFFNFACYLVYMFIFTVVAYHQPSLDQPAIPSSKATFGESMLLLG 437 LNKLLQ KWDRL+ RF FNF CYLVYM IFT VAYHQP+L++ P KAT G SMLLLG Sbjct: 301 LNKLLQAKWDRLIPRFCFNFLCYLVYMLIFTAVAYHQPALEKQGFPPLKATAGNSMLLLG 360 Query: 438 HILILLGGIYLLLGQLWYFWRRRLFIWISFMDSYFEILFLLQALLTVLSQVLRFMETEWY 497 HILILLGG+YLLLGQLWYFWRRRLFIWISFMDSYFEILFLLQALLTVLSQVL F+ EWY Sbjct: 361 HILILLGGVYLLLGQLWYFWRRRLFIWISFMDSYFEILFLLQALLTVLSQVLCFLAIEWY 420 Query: 498 LPLLVLSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVS 557 LPLLV SLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVS Sbjct: 421 LPLLVSSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVS 480 Query: 558 LSREARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDASLELFKFTIGMGELAFQEQLR 617 LSREA QE+E PYRSILDASLELFKFTIGMGELAFQEQLR Sbjct: 481 LSREA--------------------QEDEAPPYRSILDASLELFKFTIGMGELAFQEQLR 520 Query: 618 FRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNHVADNSWSIWKLQKAISVLEMENGYWW 677 FRGVVLLLLLAYVLLTYVLLLNMLIALMSETVN VA +SWSIWKLQKAISVLEMENGYWW Sbjct: 521 FRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNSVATDSWSIWKLQKAISVLEMENGYWW 580 Query: 678 CRRKKHREGRLLKVGTRGDGTPDERWCFRVEEV 710 CRRKK R G +L VGTR DG+PDERWCFRV E+ Sbjct: 581 CRRKKQRAGVMLTVGTRPDGSPDERWCFRVGEM 613 >6DVZ-A nrPDB Length = 791 Score = 841 bits (2173), Expect = 0.0, Method: Composition-based stats. Identities = 298/766 (38%), Positives = 412/766 (53%), Gaps = 76/766 (9%) Query: 29 KQEPP----PMESPFQR------EDRNSS--PQIKVNLNFIKRPPKNTSAPSQQEPDR-- 74 K PP PM+S ++ +D +S PQ V P N ++PS Sbjct: 58 KTSPPIFSKPMDSNIRQCLSGNCDDMDSPQSPQDDVT-----ETPSNPNSPSANLAKEEQ 112 Query: 75 -----FDRDRLFSVVSRGVPEELTGLLEYL-----RWNSKYLTD---SAYTEGSTGKTCL 121 + R+F+ VS G EEL LL+ L R + D T TGKTCL Sbjct: 113 RQKKKRLKKRIFAAVSEGCVEELRELLQDLQDLCRRRRGLDVPDFLMHKLTASDTGKTCL 172 Query: 122 MKAVLNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVK 181 MKA+LN+ + LL +++ +NA+ T+E Y+G +AL+IAIE+R Sbjct: 173 MKALLNINPNTKEIVRILLAFAEENDILDRFINAEYTEEAYEGQTALNIAIERRQGDITA 232 Query: 182 LLVENGADVHLRACGRFFQ-KHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLE 240 +L+ GADV+ A G FF K+Q FYFGE PL+LAACT Q ++V L+EN + + Sbjct: 233 VLIAAGADVNAHAKGVFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMEN--EQTDIT 290 Query: 241 ATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLK 300 + DS GN +LHALV +A++ + V MYD +L +LE + N+ GLTPL+ Sbjct: 291 SQDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILLRSGNW----ELETMRNNDGLTPLQ 346 Query: 301 LAAKEGKIEIFRHILQREFSG-PYQPLSRKFTEWCYGPVRVSLYDLSSVDSWEKNSVLEI 359 LAAK GK EI ++IL RE P + LSRKFT+W YGPV SLYDL++VD+ NSVLEI Sbjct: 347 LAAKMGKAEILKYILSREIKEKPLRSLSRKFTDWAYGPVSSSLYDLTNVDTTTDNSVLEI 406 Query: 360 IAFHCKSPNRHRMVVLEPLNKLLQEKWDRLVSRFFFNFACYLV-YMFIFTVVAYHQPSLD 418 I ++ NRH M+ LEPL+ LL KW + FF C+ Y T+V+Y++P D Sbjct: 407 IVYNTNIDNRHEMLTLEPLHTLLHTKWKKFAKYMFFLSFCFYFFYNITLTLVSYYRPRED 466 Query: 419 QPAIPSSKATFGESML-LLGHILILLGGIYLLLGQ-LWYFWRRRLFIWISFMDSYFEILF 476 + T S L LLG + +L+ + + + + F R + D++F +F Sbjct: 467 EDLPHPLALTHKMSWLQLLGRMFVLIWATCISVKEGIAIFLLRPSDLQSILSDAWFHFVF 526 Query: 477 LLQALLTVLSQVLRFMETEWYLPLLVLSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRD 536 +QA+L +LS L + YL LVL++ LGW N+L YTRGFQ G+YSVMIQKVIL D Sbjct: 527 FVQAVLVILSVFLYLFAYKEYLACLVLAMALGWANMLAYTRGFQSMGMYSVMIQKVILHD 586 Query: 537 LLRFLLVYLVFLFGFAVALVSLSREARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDA 596 +L+FL VY++FL GF VAL SL + K ++ + Y S DA Sbjct: 587 VLKFLFVYILFLLGFGVALASLIEKCSKDK------------------KDCSSYGSFSDA 628 Query: 597 SLELFKFTIGMGELAFQEQLRFRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNHVADNS 656 LELFK TIG+G+L Q+ + + L LL+ YV+LT+VLLLNMLIALM ETV +V+ S Sbjct: 629 VLELFKLTIGLGDLNIQQNSTYPILFLFLLITYVILTFVLLLNMLIALMGETVENVSKES 688 Query: 657 WSIWKLQKAISVLEMENGYWWCRRKKHREGRLLKVGTRGDGTPDERWCFRVEEVNWAAWE 716 IW+LQ+A ++LE E R + R G L KV D R C R+ EV W W+ Sbjct: 689 ERIWRLQRARTILEFEKMLPEWLRSRFRMGELCKVADE-----DFRLCLRINEVKWTEWK 743 Query: 717 KTLPTLSEDPSGP--------GITGNKKNPTSKPGKNSASEEDHLP 754 + L+EDP GP I + ++ SK + E D P Sbjct: 744 THVSFLNEDP-GPIRRTADLNKIQDSSRS-NSKTTLYAFDELDEFP 787 >6MHW-A nrPDB Length = 826 Score = 815 bits (2105), Expect = 0.0, Method: Composition-based stats. Identities = 298/766 (38%), Positives = 413/766 (53%), Gaps = 75/766 (9%) Query: 28 GKQEPP----PMESPFQR------EDRNSS--PQIKVNLNFIKRPPKNTSAPSQQEPDR- 74 K PP PM+S ++ +D +S PQ V P N ++PS Q Sbjct: 58 AKTSPPVFSKPMDSNIRQCISGNCDDMDSPQSPQDDVT-----ETPSNPNSPSAQLAKEE 112 Query: 75 ------FDRDRLFSVVSRGVPEELTGLLEYL-----RWNSKYLTD---SAYTEGSTGKTC 120 + R+F+ VS G EEL LL L R + + + D T TGKTC Sbjct: 113 QRRKKRRLKKRIFAAVSEGCVEELVELLVELQELCRRRHDEDVPDFLMHKLTASDTGKTC 172 Query: 121 LMKAVLNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCV 180 LMKA+LN+ + LL +++ +NA+ T+E Y+G +AL+IAIE+R Sbjct: 173 LMKALLNINPNTKEIVRILLAFAEENDILGRFINAEYTEEAYEGQTALNIAIERRQGDIA 232 Query: 181 KLLVENGADVHLRACGRFFQ-KHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASL 239 LL+ GADV+ A G FF K+Q FYFGE PL+LAACT Q ++V L+E H+ + Sbjct: 233 ALLIAAGADVNAHAKGAFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLME--HEQTDI 290 Query: 240 EATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPL 299 + DS GN +LHALV +A++ + V MYD +L +LE N+ GLTPL Sbjct: 291 TSRDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILLRSGNW----ELETTRNNDGLTPL 346 Query: 300 KLAAKEGKIEIFRHILQREFSGP-YQPLSRKFTEWCYGPVRVSLYDLSSVDSWEKNSVLE 358 +LAAK GK EI ++IL RE + LSRKFT+W YGPV SLYDL++VD+ NSVLE Sbjct: 347 QLAAKMGKAEILKYILSREIKEKRLRSLSRKFTDWAYGPVSSSLYDLTNVDTTTDNSVLE 406 Query: 359 IIAFHCKSPNRHRMVVLEPLNKLLQEKWDRLVSRFFFNFACYLV-YMFIFTVVAYHQPSL 417 I ++ NRH M+ LEPL+ LL KW + FF C+ Y T+V+Y++P Sbjct: 407 ITVYNTNIDNRHEMLTLEPLHTLLHMKWKKFAKHMFFLSFCFYFFYNITLTLVSYYRPRE 466 Query: 418 DQPAIPSSKATFGESML-LLGHILILLGGIYLLLGQ-LWYFWRRRLFIWISFMDSYFEIL 475 ++ T L LLG + +L+ + + + + + F R + D++F + Sbjct: 467 EEAIPHPLALTHKMGWLQLLGRMFVLIWAMCISVKEGIAIFLLRPSDLQSILSDAWFHFV 526 Query: 476 FLLQALLTVLSQVLRFMETEWYLPLLVLSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILR 535 F +QA+L +LS L + YL LVL++ LGW N+LYYTRGFQ G+YSVMIQKVIL Sbjct: 527 FFIQAVLVILSVFLYLFAYKEYLACLVLAMALGWANMLYYTRGFQSMGMYSVMIQKVILH 586 Query: 536 DLLRFLLVYLVFLFGFAVALVSLSREARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILD 595 D+L+FL VY+VFL GF VAL SL + ++ + Y S D Sbjct: 587 DVLKFLFVYIVFLLGFGVALASLIEKCPKDN------------------KDCSSYGSFSD 628 Query: 596 ASLELFKFTIGMGELAFQEQLRFRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNHVADN 655 A LELFK TIG+G+L Q+ ++ + L LL+ YV+LT+VLLLNMLIALM ETV +V+ Sbjct: 629 AVLELFKLTIGLGDLNIQQNSKYPILFLFLLITYVILTFVLLLNMLIALMGETVENVSKE 688 Query: 656 SWSIWKLQKAISVLEMENGYWWCRRKKHREGRLLKVGTRGDGTPDERWCFRVEEVNWAAW 715 S IW+LQ+A ++LE E R + R G L KV D R C R+ EV W W Sbjct: 689 SERIWRLQRARTILEFEKMLPEWLRSRFRMGELCKV-----AEDDFRLCLRINEVKWTEW 743 Query: 716 EKTLPTLSEDPSGP-------GITGNKKNPTSKPGKNSASEEDHLP 754 + + L+EDP GP I + +N SK N+ E + P Sbjct: 744 KTHVSFLNEDP-GPVRRTDFNKIQDSSRN-NSKTTLNAFEEVEEFP 787 >6E2G-A nrPDB Length = 727 Score = 689 bits (1778), Expect = 0.0, Method: Composition-based stats. Identities = 188/677 (27%), Positives = 312/677 (46%), Gaps = 97/677 (14%) Query: 62 KNTSAPSQQEPDRFDRDRLFS-----VVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGST 116 + + A S+ E + + R++ + L LL K+ + +G+ Sbjct: 26 RESWAQSRDEQNLLQQKRIWESPLLLAAKENNVQALIKLL-------KFEGCEVHQKGAM 78 Query: 117 GKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRS 176 G+T L A L D + A ++ + + LV T E Y+G +ALHIA+ ++ Sbjct: 79 GETALHIAAL--YDNLEAAMVLMEAAPE-------LVFEPMTSELYEGQTALHIAVINQN 129 Query: 177 LQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQP 236 + V+ L+ GA V RA G F Y+GE PLS AAC ++V L+E+ Sbjct: 130 VNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEHG--- 186 Query: 237 ASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGL 296 A + A DSLGNTVLH L++ N MY+ LL LE + N+QGL Sbjct: 187 ADIRAQDSLGNTVLHILIL-----QPNKTFACQMYNLLLSYDGG-DHLKSLELVPNNQGL 240 Query: 297 TPLKLAAKEGKIEIFRHILQREFSGPYQPLSRKFTEWCYGPVRVSLYDLSSVDS-WEKNS 355 TP KLA EG I +F+H++Q+ RK +W YGP+ +LYDL+ +DS + S Sbjct: 241 TPFKLAGVEGNIVMFQHLMQK----------RKHIQWTYGPLTSTLYDLTEIDSSGDDQS 290 Query: 356 VLEIIAFHCKSPNRHRMVVLEPLNKLLQEKWDRLVSRFFFNF-ACYLVYMFIFTVVAYHQ 414 +LE+I K R +++ P+ +L+ KW R +F A Y++Y+ FT+ ++ Sbjct: 291 LLELIVTTKKREAR-QILDQTPVKELVSLKWKRYGRPYFCVLGAIYVLYIICFTMCCVYR 349 Query: 415 PS---------------LDQPAIPSSKATFGESMLLLGHILILLGGIYLLLGQLWYFWRR 459 P L Q + + T + + L+G ++ ++G + +LL ++ +R Sbjct: 350 PLKPRITNRTNPRDNTLLQQKLLQEAYVTPKDDLRLVGELVSIVGAVIILLVEIPDIFRL 409 Query: 460 RL--FIWISFMDSYFEILFLLQALLTVLSQVLRFMETEWYLPLLVLSLVLGWLNLLYYTR 517 + F + + F ++ + A + +++ V+R ++ + + +LVLGW N++Y+ R Sbjct: 410 GVTRFFGQTILGGPFHVIIVTYAFMVLVTMVMRLTNSDGEVVPMSFALVLGWCNVMYFAR 469 Query: 518 GFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVSLSREARSPKAPEDNNSTVTE 577 GFQ G +++MIQK+I DL+RF + V + GFA A Sbjct: 470 GFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFY--------------------- 508 Query: 578 QPTVGQEEEPAPYRSILDASLELFK-----FTIGMGELAFQEQLRFRGVVLLLLLAYVLL 632 + Q E+P D + LF TI G + L F + + A+ ++ Sbjct: 509 --IIFQTEDPDELGHFYDYPMALFSTFELFLTIIDGPANYDVDLPF--MYSITYAAFAII 564 Query: 633 TYVLLLNMLIALMSETVNHVADNSWSIWKLQKAISVLEMENGYWWCRRKKHREGRLLKVG 692 +L+LN+LIA+M +T VA +W+ Q + + +E C R G + Sbjct: 565 ATLLMLNLLIAMMGDTHWRVAHERDELWRAQVVATTVMLERKLPRCLWP--RSG----IC 618 Query: 693 TRGDGTPDERWCFRVEE 709 R G D RW RVE+ Sbjct: 619 GREYGLGD-RWFLRVED 634 >6BOA-A nrPDB Length = 742 Score = 684 bits (1765), Expect = 0.0, Method: Composition-based stats. Identities = 191/677 (28%), Positives = 311/677 (45%), Gaps = 96/677 (14%) Query: 62 KNTSAPSQQEPDRFDRDRLFS-----VVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGST 116 + + A S+ E + + R++ + L LL KY + G+ Sbjct: 26 RESWAQSRDEQNLLQQKRIWESPLLLAAKDNDVQALNKLL-------KYEDCKVHQRGAM 78 Query: 117 GKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRS 176 G+T L A L D + A ++ + + LV T E Y+G +ALHIA+ ++ Sbjct: 79 GETALHIAAL--YDNLEAAMVLMEAAPE-------LVFEPMTSELYEGQTALHIAVVNQN 129 Query: 177 LQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQP 236 + V+ L+ A V RA G F++ YFGE PLS AAC ++V L+E+ Sbjct: 130 MNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHG--- 186 Query: 237 ASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGL 296 A + A DSLGNTVLH L++ N MY+ LL L+ + NHQGL Sbjct: 187 ADIRAQDSLGNTVLHILIL-----QPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQGL 241 Query: 297 TPLKLAAKEGKIEIFRHILQREFSGPYQPLSRKFTEWCYGPVRVSLYDLSSVDS-WEKNS 355 TP KLA EG +F+H++Q+ RK T+W YGP+ +LYDL+ +DS ++ S Sbjct: 242 TPFKLAGVEGNTVMFQHLMQK----------RKHTQWTYGPLTSTLYDLTEIDSSGDEQS 291 Query: 356 VLEIIAFHCKSPNRHRMVVLEPLNKLLQEKWDRLVSRFFFNF-ACYLVYMFIFTVVAYHQ 414 +LE+I K R +++ P+ +L+ KW R +F A YL+Y+ FT+ ++ Sbjct: 292 LLELIITTKKREAR-QILDQTPVKELVSLKWKRYGRPYFCMLGAIYLLYIICFTMCCIYR 350 Query: 415 PS---------------LDQPAIPSSKATFGESMLLLGHILILLGGIYLLLGQLWYFWRR 459 P L Q + + T + + L+G ++ ++G I +LL ++ +R Sbjct: 351 PLKPRTNNRTSPRDNTLLQQKLLQEAYMTPKDDIRLVGELVTVIGAIIILLVEVPDIFRM 410 Query: 460 RL--FIWISFMDSYFEILFLLQALLTVLSQVLRFMETEWYLPLLVLSLVLGWLNLLYYTR 517 + F + + F +L + A + +++ V+R + + + +LVLGW N++Y+ Sbjct: 411 GVTRFFGQTILGGPFHVLIITYAFMVLVTMVMRLISASGEVVPMSFALVLGWCNVMYFAE 470 Query: 518 GFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVSLSREARSPKAPEDNNSTVTE 577 GFQ G +++MIQK+I DL+RF + V + GFA A Sbjct: 471 GFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFY--------------------- 509 Query: 578 QPTVGQEEEPAPYRSILDASLELFK-----FTIGMGELAFQEQLRFRGVVLLLLLAYVLL 632 + Q E+P D + LF TI G + L F + + A+ ++ Sbjct: 510 --IIFQTEDPEELGHFYDYPMALFSTFELFLTIIDGPANYNVDLPF--MYSITYAAFAII 565 Query: 633 TYVLLLNMLIALMSETVNHVADNSWSIWKLQKAISVLEMENGYWWCRRKKHREGRLLKVG 692 +L+LN+LIA+M +T VA +W+ Q + + +E C R G + Sbjct: 566 ATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVATTVMLERKLPRCLWP--RSG----IC 619 Query: 693 TRGDGTPDERWCFRVEE 709 R G D RW RVE+ Sbjct: 620 GREYGLGD-RWFLRVED 635 >6DMR-A nrPDB Length = 730 Score = 658 bits (1698), Expect = 0.0, Method: Composition-based stats. Identities = 179/622 (28%), Positives = 292/622 (46%), Gaps = 74/622 (11%) Query: 107 TDSAYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHS 166 + G+ G+T L A L D + A + + + + P L E + G + Sbjct: 69 SCDFQQRGAVGETALHVAAL--YDNLEAATLLMEAAPELAKEPALC-------EPFVGQT 119 Query: 167 ALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVV 226 ALHIA+ ++L V+ L+ GA V RA G F++ Y+GE PLS AAC ++V Sbjct: 120 ALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIV 179 Query: 227 TYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQ 286 L+E+ A + A DSLGNTVLH L++ N MY+ LL Sbjct: 180 RLLIEHG---ADIRAQDSLGNTVLHILIL-----QPNKTFACQMYNLLLSYDEHSDHLQS 231 Query: 287 LEEISNHQGLTPLKLAAKEGKIEIFRHILQREFSGPYQPLSRKFTEWCYGPVRVSLYDLS 346 LE + NHQGLTP KLA EG +F+H++Q+ RK +W GP+ +LYDL+ Sbjct: 232 LELVPNHQGLTPFKLAGVEGNTVMFQHLMQK----------RKHVQWTCGPLTSTLYDLT 281 Query: 347 SVDSW-EKNSVLEIIAFHCKSPNRHRMVVLEPLNKLLQEKWDRLVSRFFFNFAC-YLVYM 404 +DSW E+ S LE++ K R +++ P+ +L+ KW + +F A Y++YM Sbjct: 282 EIDSWGEELSFLELVVSSKKREAR-QILEQTPVKELVSFKWKKYGRPYFCVLASLYILYM 340 Query: 405 FIFTVVAYHQPS---------------LDQPAIPSSKATFGESMLLLGHILILLGGIYLL 449 FT ++P L Q + + T +++ L+G ++ + G + +L Sbjct: 341 ICFTTCCIYRPLKLRDDNRTDPRDITILQQKLLQEAYVTHQDNIRLVGELVTVTGAVIIL 400 Query: 450 LGQLWYFWR--RRLFIWISFMDSYFEILFLLQALLTVLSQVLRFMETEWYLPLLVLSLVL 507 L ++ +R + + + F ++ + A L +L+ V+R + L +LVL Sbjct: 401 LLEIPDIFRVGASRYFGQTILGGPFHVIIITYASLVLLTMVMRLTNMNGEVVPLSFALVL 460 Query: 508 GWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVSLSREARSPKA 567 GW +++Y+ RGFQ G +++MIQK+I DL+RF + V + GFA A ++ + P Sbjct: 461 GWCSVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAF-HITFQTEDP-- 517 Query: 568 PEDNNSTVTEQPTVGQEEEPAPYRSILDASLELFKFTIGMGELAFQEQLRFRGVVLLLLL 627 +N ++ PT L ++ ELF TI G + L F + + Sbjct: 518 --NNLGEFSDYPTA------------LFSTFELF-LTIIDGPANYSVDLPF--MYCITYA 560 Query: 628 AYVLLTYVLLLNMLIALMSETVNHVADNSWSIWKLQKAISVLEMENGYWWCRRKKHREGR 687 A+ ++ +L+LN+ IA+M +T VA +W+ Q + + +E R G Sbjct: 561 AFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVATTVMLERKMPRFLWP--RSG- 617 Query: 688 LLKVGTRGDGTPDERWCFRVEE 709 + G D RW RVE Sbjct: 618 ---ICGYEYGLGD-RWFLRVEN 635 >2ETB-A nrPDB Length = 256 Score = 414 bits (1064), Expect = e-116, Method: Composition-based stats. Identities = 246/256 (96%), Positives = 246/256 (96%) Query: 75 FDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNA 134 FDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNA Sbjct: 1 FDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNA 60 Query: 135 CIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRA 194 CIMPLLQIDKDSGNPK LVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRA Sbjct: 61 CIMPLLQIDKDSGNPKPLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRA 120 Query: 195 CGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALV 254 CGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALV Sbjct: 121 CGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALV 180 Query: 255 MIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHI 314 MIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHI Sbjct: 181 MIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHI 240 Query: 315 LQREFSGPYQPLSRKF 330 LQREFSG Sbjct: 241 LQREFSGAAAHHHHHH 256 >2F37-A nrPDB Length = 251 Score = 402 bits (1034), Expect = e-112, Method: Composition-based stats. Identities = 215/251 (85%), Positives = 231/251 (92%) Query: 70 QEPDRFDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQ 129 +P+RFDRDRLF+ VSRGVPE+L GL EYL SKYLTDS YTEGSTGKTCLMKAVLNL+ Sbjct: 1 PDPNRFDRDRLFNAVSRGVPEDLAGLPEYLSKTSKYLTDSEYTEGSTGKTCLMKAVLNLK 60 Query: 130 DGVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGAD 189 DGVNACI+PLLQID+DSGNP+ LVNAQCTD++Y+GHSALHIAIEKRSLQCVKLLVENGA+ Sbjct: 61 DGVNACILPLLQIDRDSGNPQPLVNAQCTDDYYRGHSALHIAIEKRSLQCVKLLVENGAN 120 Query: 190 VHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTV 249 VH RACGRFFQK QGTCFYFGELPLSLAACTKQWDVV+YLLENPHQPASL+ATDS GNTV Sbjct: 121 VHARACGRFFQKGQGTCFYFGELPLSLAACTKQWDVVSYLLENPHQPASLQATDSQGNTV 180 Query: 250 LHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIE 309 LHALVMI+DNS EN ALV MYDGLLQ GARLCPTVQLE+I N Q LTPLKLAAKEGKIE Sbjct: 181 LHALVMISDNSAENIALVTSMYDGLLQAGARLCPTVQLEDIRNLQDLTPLKLAAKEGKIE 240 Query: 310 IFRHILQREFS 320 IFRHILQREFS Sbjct: 241 IFRHILQREFS 251 >4DX2-A nrPDB Length = 259 Score = 372 bits (956), Expect = e-103, Method: Composition-based stats. Identities = 136/250 (54%), Positives = 169/250 (67%), Gaps = 1/250 (0%) Query: 74 RFDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVN 133 F+R LF +VSRG +L GLL +L + K LTD + E STGKTCL KA+LNL +G N Sbjct: 1 MFNRPILFDIVSRGSTADLDGLLPFLLTHKKRLTDEEFREPSTGKTCLPKALLNLSNGRN 60 Query: 134 ACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLR 193 I LL I + +GN + +N+ D +Y+G +ALHIAIE+R V+LLV GADVH + Sbjct: 61 DTIPVLLDIAERTGNMREFINSPFRDIYYRGQTALHIAIERRCKHYVELLVAQGADVHAQ 120 Query: 194 ACGRFFQ-KHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHA 252 A GRFFQ K +G FYFGELPLSLAACT Q +V YL ENPH+ A + DS GNTVLHA Sbjct: 121 ARGRFFQPKDEGGYFYFGELPLSLAACTNQPHIVNYLTENPHKKADMRRQDSRGNTVLHA 180 Query: 253 LVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFR 312 LV IADN+ EN+ V MYD LL ARL P LE + N+ GL+PL +AAK GKI IF+ Sbjct: 181 LVAIADNTRENTKFVTKMYDLLLLKCARLFPDSNLEAVLNNDGLSPLMMAAKTGKIGIFQ 240 Query: 313 HILQREFSGP 322 HI++RE + Sbjct: 241 HIIRREVTDE 250 >3W9G-A nrPDB Length = 260 Score = 372 bits (954), Expect = e-103, Method: Composition-based stats. Identities = 137/250 (54%), Positives = 169/250 (67%), Gaps = 1/250 (0%) Query: 73 DRFDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGV 132 F+R LF +VSRG P+ L GLL +L + K LTD + E STGKTCL KA+LNL G Sbjct: 2 KVFNRPILFDIVSRGSPDGLEGLLSFLLTHKKRLTDEEFREPSTGKTCLPKALLNLSAGR 61 Query: 133 NACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHL 192 N I LL I + +GN + +N+ D +Y+G +ALHIAIE+R V+LLVE GADVH Sbjct: 62 NDTIPILLDIAEKTGNMREFINSPFRDVYYRGQTALHIAIERRCKHYVELLVEKGADVHA 121 Query: 193 RACGRFFQ-KHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLH 251 +A GRFFQ K +G FYFGELPLSLAACT Q +V YL EN H+ A L DS GNTVLH Sbjct: 122 QARGRFFQPKDEGGYFYFGELPLSLAACTNQPHIVHYLTENGHKQADLRRQDSRGNTVLH 181 Query: 252 ALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIF 311 ALV IADN+ EN+ V MYD LL A+L P LE + N+ GL+PL +AAK GKI IF Sbjct: 182 ALVAIADNTRENTKFVTKMYDLLLIKCAKLFPDTNLEALLNNDGLSPLMMAAKTGKIGIF 241 Query: 312 RHILQREFSG 321 +HI++RE + Sbjct: 242 QHIIRREIAD 251 >2NYJ-A nrPDB Length = 273 Score = 366 bits (940), Expect = e-101, Method: Composition-based stats. Identities = 132/260 (50%), Positives = 180/260 (69%), Gaps = 1/260 (0%) Query: 64 TSAPSQQEPDRFDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMK 123 + + ++ P +DR +F V++ +EL LL +L+ + K LTDS + + TGKTCL+K Sbjct: 1 SVSAGEKPPRLYDRRSIFDAVAQSNCQELESLLPFLQRSKKRLTDSEFKDPETGKTCLLK 60 Query: 124 AVLNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLL 183 A+LNL +G N I LL + + + + K VNA TD +Y+G +ALHIAIE+R++ V LL Sbjct: 61 AMLNLHNGQNDTIALLLDVARKTDSLKQFVNASYTDSYYKGQTALHIAIERRNMTLVTLL 120 Query: 184 VENGADVHLRACGRFFQKHQGT-CFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEAT 242 VENGADV A G FF+K +G FYFGELPLSLAACT Q +V +LL+N QPA + A Sbjct: 121 VENGADVQAAANGDFFKKTKGRPGFYFGELPLSLAACTNQLAIVKFLLQNSWQPADISAR 180 Query: 243 DSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLA 302 DS+GNTVLHALV +ADN+ +N+ V MY+ +L +GA+L PT++LEEI+N +GLTPL LA Sbjct: 181 DSVGNTVLHALVEVADNTVDNTKFVTSMYNEILILGAKLHPTLKLEEITNRKGLTPLALA 240 Query: 303 AKEGKIEIFRHILQREFSGP 322 A GKI + +ILQRE P Sbjct: 241 ASSGKIGVLAYILQREIHEP 260 >4N5Q-A nrPDB Length = 257 Score = 317 bits (811), Expect = 1e-86, Method: Composition-based stats. Identities = 103/257 (40%), Positives = 144/257 (56%), Gaps = 15/257 (5%) Query: 74 RFDRDRLFSVVSRGVPEELTGLLEYL-----RWNSKYLTD---SAYTEGSTGKTCLMKAV 125 + R+F+ VS G EEL LL+ L R + D T TGKTCLMKA+ Sbjct: 1 MRLKKRIFAAVSEGCVEELRELLQDLQDLCRRRRGLDVPDFLMHKLTASDTGKTCLMKAL 60 Query: 126 LNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVE 185 LN+ + LL +++ +NA+ T+E Y+G +AL+IAIE+R +L+ Sbjct: 61 LNINPNTKEIVRILLAFAEENDILDRFINAEYTEEAYEGQTALNIAIERRQGDITAVLIA 120 Query: 186 NGADVHLRACGRFFQ-KHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDS 244 GADV+ A G FF K+Q FYFGE PL+LAACT Q ++V L+EN + + + DS Sbjct: 121 AGADVNAHAKGVFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMEN--EQTDITSQDS 178 Query: 245 LGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAK 304 GN +LHALV +A++ + V MYD +L +LE + N+ GLTPL+LAAK Sbjct: 179 RGNNILHALVTVAEDFKTQNDFVKRMYDMILLRSGNW----ELETMRNNDGLTPLQLAAK 234 Query: 305 EGKIEIFRHILQREFSG 321 GK EI ++IL RE Sbjct: 235 MGKAEILKYILSREIKE 251 >2RFA-A nrPDB Length = 232 Score = 250 bits (638), Expect = 2e-66, Method: Composition-based stats. Identities = 76/222 (34%), Positives = 111/222 (50%), Gaps = 18/222 (8%) Query: 96 LEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKLLVNA 155 ++ L K+ + G+ G+T L A L D + A ++ + + LV Sbjct: 16 VQALSKLLKFEGCEVHQRGAMGETALHIAAL--YDNLEAAMVLMEAAPE-------LVFE 66 Query: 156 QCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLS 215 T E Y+G +ALHIA+ +++ V+ L+ GA V RA G F Y+GE PLS Sbjct: 67 PMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLS 126 Query: 216 LAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLL 275 AAC ++V L+E+ A + A DSLGNTVLH L++ N MY+ LL Sbjct: 127 FAACVGSEEIVRLLIEHG---ADIRAQDSLGNTVLHILIL-----QPNKTFACQMYNLLL 178 Query: 276 QMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQR 317 LE + N+QGLTP KLA EG I +F+H++Q+ Sbjct: 179 SYDGG-DHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQK 219 >6G1K-A nrPDB Length = 921 Score = 223 bits (569), Expect = 2e-58, Method: Composition-based stats. Identities = 70/292 (23%), Positives = 124/292 (42%), Gaps = 34/292 (11%) Query: 392 RFFFNFACYLVYMFIFTVVAYHQPSLDQPAIPSSKATFGESMLLLGHILILLGGIYLLLG 451 +F + A YL ++F+ + + H + P K T E M+L +LG I+ + Sbjct: 365 KFICHTASYLTFLFLLLLASQH-IVSNNPDRQGPKPTTVEWMILPW----VLGFIWTEIK 419 Query: 452 QLWYF-WRRRLFIWISFMDSYFEILFLLQALLTVLSQV----LRFMET-EWYLPLLVLSL 505 Q+W ++ + W + MD L+L L +++ V + +T E + P LV Sbjct: 420 QMWDGGFQDYIHDWWNLMDFVMNSLYLATISLKIVAYVKYSGCKPRDTWEMWHPTLVAEA 479 Query: 506 VLGWLNLLYYTR------GFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVSLS 559 V N+ R H G + + +++L D+L+FL +Y + L FA L L Sbjct: 480 VFAIANIFSSLRLISLFTANSHLGPLQISLGRMLL-DILKFLFIYCLVLLAFANGLNQLY 538 Query: 560 REARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDASLELFKFTIGMGEL------AFQ 613 NS + E + + ++ + LF G+ L A Sbjct: 539 FYYE--------NSEGMTCKGIRCERQNNAFSTLFETLQSLFWSIFGLISLYVTNVKADH 590 Query: 614 EQLRFRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNHVADNSWSIWKLQKA 665 + F G + Y +++ V+LLNMLIA+M+ + H+AD++ WK + Sbjct: 591 KFTEFVGATMFG--TYNVISLVVLLNMLIAMMNNSYQHIADHADIEWKFART 640 Score = 35.1 bits (79), Expect = 0.11, Method: Composition-based stats. Identities = 35/164 (21%), Positives = 64/164 (39%), Gaps = 33/164 (20%) Query: 171 AIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLL 230 A+EK VKL +E A++ +F+ + G L +A + +++ LL Sbjct: 39 AVEKGDYASVKLALEE-AEI-------YFKININCIDPLGRTALLIAIENENLEIIELLL 90 Query: 231 ENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQM----GARLCPTVQ 286 +G+ +LHA+ V+ + LL G + P + Sbjct: 91 SFNVY---------VGDALLHAI----------RKEVVGAVELLLNHKKPSGEKQVPPIL 131 Query: 287 LEEISNHQ--GLTPLKLAAKEGKIEIFRHILQREFSGPYQPLSR 328 L++ + +TP+ LAA EI + ++Q+ S P R Sbjct: 132 LDKQFSDFTPDITPIILAAHTNNYEIIKMLVQKGVSVPQPHEVR 175 Score = 32.4 bits (72), Expect = 0.82, Method: Composition-based stats. Identities = 24/120 (20%), Positives = 44/120 (36%), Gaps = 28/120 (23%) Query: 140 LQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADV--------- 190 +++ + +N C D G +AL IAIE +L+ ++LL+ V Sbjct: 48 VKLALEEAEIYFKININCIDPL--GRTALLIAIENENLEIIELLLSFNVYVGDALLHAIR 105 Query: 191 ------------HLRACGR-----FFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENP 233 H + G Q + F P+ LAA T ++++ L++ Sbjct: 106 KEVVGAVELLLNHKKPSGEKQVPPILLDKQFSDFTPDITPIILAAHTNNYEIIKMLVQKG 165 >5Z96-A nrPDB Length = 755 Score = 208 bits (529), Expect = 7e-54, Method: Composition-based stats. Identities = 121/627 (19%), Positives = 228/627 (36%), Gaps = 125/627 (19%) Query: 162 YQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTK 221 Y G + LH AI K + V+LL+ + + Q + F P+ LAA T Sbjct: 95 YVGDALLH-AIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSEFTPDITPIILAAHTN 153 Query: 222 QWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARL 281 ++++ L++ + S+ + + + +S +S +++Y L Sbjct: 154 NYEIIKLLVQ---KGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKAL------- 203 Query: 282 CPTVQLEEISNHQG-LTPLKLAAKEGKIEIFRHILQREFSGPYQPLSRKFTEWCYGPV-- 338 + L +S+ LT +L+ + ++ ++ EF Y+ LSR+ ++ + Sbjct: 204 -ASPSLIALSSEDPFLTAFQLSWELQELSK----VENEFKSEYEELSRQCKQFAKDLLDQ 258 Query: 339 -RVSLYDLSSVDSWEKNSVLE------IIAFHCKSPNRHRMVVLEP-LNKLLQEKW---- 386 R S ++ + NS++E + R + V +P +LL +W Sbjct: 259 TRSSRELEIILNYRDDNSLIEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLASRWYDEF 318 Query: 387 -----------------------------------------DRLVSRFFFNFACYLVYMF 405 + +F + A YL ++F Sbjct: 319 PGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTASYLTFLF 378 Query: 406 IFTVVAYH--QPSLDQPAIPSSKATFGESMLLLGHILILLGGIYLLLGQLWYF-WRRRLF 462 + + + H + L++ P T E M+L +LG I+ + Q+W + + Sbjct: 379 LLLLASQHIDRSDLNRQGPPP---TIVEWMILPW----VLGFIWGEIKQMWDGGLQDYIH 431 Query: 463 IWISFMDSYFEILFLLQALLTVLSQV----LRFMET-EWYLPLLVLSLVLGWLNLLYYTR 517 W + MD L+L L +++ V L E+ + + P LV + N+ R Sbjct: 432 DWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHPTLVAEALFAIANIFSSLR 491 Query: 518 ------GFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVSLSREARSPKAPEDN 571 H G + + +++L D+L+FL +Y + L FA L L K Sbjct: 492 LISLFTANSHLGPLQISLGRMLL-DILKFLFIYCLVLLAFANGLNQLYFYYEETK----- 545 Query: 572 NSTVTEQPTVGQEEEPAPYRSILDASLELFKFTIGMGEL------AFQEQLRFRGVVLLL 625 + E++ + ++ + LF G+ L A E F G + Sbjct: 546 ---GLSCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFG 602 Query: 626 LLAYVLLTYVLLLNMLIALMSETVNHVADNSWSIWKLQKAISVLEMENGYWWCRRKKHRE 685 Y +++ V+LLNMLIA+M+ + +AD++ WK + W E Sbjct: 603 --TYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFART--------KLWM---SYFEE 649 Query: 686 GRLLKVGTRGDGTPDERWCFRVEEVNW 712 G L +P W V W Sbjct: 650 GGTLPTPFNVIPSPKSLWYL----VKW 672 >5AQ7-A nrPDB Length = 418 Score = 140 bits (352), Expect = 2e-33, Method: Composition-based stats. Identities = 52/208 (25%), Positives = 77/208 (37%), Gaps = 47/208 (22%) Query: 114 GSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIE 173 GK L A + G + + LL A G + LH+A Sbjct: 12 SDLGKKLLEAA----RAGQDDEVRILLANG-----------ADVNTADETGFTPLHLAAW 56 Query: 174 KRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENP 233 + L V++L++NGADV+ G PL LAA T ++V LL+N Sbjct: 57 EGHLGIVEVLLKNGADVNA-------------NDERGHTPLHLAAYTGHLEIVEVLLKNG 103 Query: 234 HQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNH 293 A + ATD +G LH M + + LL+ GA + + + Sbjct: 104 ---AGVNATDVIGTAPLHLAAMWG---------YKEIVEVLLKAGADV-------DAQDK 144 Query: 294 QGLTPLKLAAKEGKIEIFRHILQREFSG 321 G PL LAA +G EI ++ Sbjct: 145 FGKRPLWLAADQGHAEIAAKLVAARLKA 172 >6FES-A nrPDB Length = 367 Score = 120 bits (301), Expect = 2e-27, Method: Composition-based stats. Identities = 51/206 (24%), Positives = 74/206 (35%), Gaps = 48/206 (23%) Query: 114 GSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIE 173 GK L A + G + + LL A G + LH+A Sbjct: 4 SDLGKKLLEAA----RAGQDDEVRILLANG-----------ADVNTADETGFTPLHLAAW 48 Query: 174 KRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENP 233 + L V++L++NGADV+ G PL LAA T ++V LL+N Sbjct: 49 EGHLGIVEVLLKNGADVNA-------------NDERGHTPLHLAAYTGHLEIVEVLLKNG 95 Query: 234 HQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNH 293 A + ATD +G LH M + + LL+ GA + Sbjct: 96 ---AGVNATDVIGTAPLHLAAMWGHE---------EIVEVLLKNGADAR-------AQDK 136 Query: 294 QGLTPLKLAAKEGKIEIFRHILQREF 319 G TP LA G E + ++E Sbjct: 137 FGKTPEDLARDNGY-ESVARLARKEI 161 >5AQA-A nrPDB Length = 418 Score = 119 bits (298), Expect = 5e-27, Method: Composition-based stats. Identities = 44/167 (26%), Positives = 65/167 (38%), Gaps = 32/167 (19%) Query: 155 AQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPL 214 A G + LH+A L+ V++L+++GADV FG PL Sbjct: 38 ADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVDAS-------------DVFGYTPL 84 Query: 215 SLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGL 274 LAA ++V LL+N A + A DS G T LH + + L Sbjct: 85 HLAAYWGHLEIVEVLLKNG---ADVNAMDSDGMTPLHLAAKWG---------YKEIVEVL 132 Query: 275 LQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQREFSG 321 L+ GA + + + G PL LAA +G EI ++ Sbjct: 133 LKAGADV-------DAQDKFGKRPLWLAADQGHAEIAAKLVAARLKA 172 >5AQ9-A nrPDB Length = 422 Score = 105 bits (263), Expect = 6e-23, Method: Composition-based stats. Identities = 41/153 (26%), Positives = 59/153 (38%), Gaps = 32/153 (20%) Query: 155 AQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPL 214 A G + LH+A L+ V++L+++GADV FG PL Sbjct: 38 ADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVDAS-------------DVFGYTPL 84 Query: 215 SLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGL 274 LAA ++V LL+N A + A DS G T LH + + + L Sbjct: 85 HLAAYWGHLEIVEVLLKNG---ADVNAMDSDGMTPLHLAAKWG---------YLEIVEVL 132 Query: 275 LQMGARLCPTVQLEEISNHQGLTPLKLAAKEGK 307 L+ GA + + G TP LA G Sbjct: 133 LKHGADV-------NAQDKFGKTPFDLADDNGN 158 Score = 87.9 bits (216), Expect = 1e-17, Method: Composition-based stats. Identities = 40/146 (27%), Positives = 62/146 (42%), Gaps = 32/146 (21%) Query: 171 AIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLL 230 A V++L+ NGADV+ G PL LAA + ++V LL Sbjct: 21 AARAGQDDEVRILMANGADVNAADNT-------------GTTPLHLAAYSGHLEIVEVLL 67 Query: 231 ENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEI 290 ++ A ++A+D G T LH + + + LL+ GA + Sbjct: 68 KHG---ADVDASDVFGYTPLHLAAYWGH---------LEIVEVLLKNGADVN-------A 108 Query: 291 SNHQGLTPLKLAAKEGKIEIFRHILQ 316 + G+TPL LAAK G +EI +L+ Sbjct: 109 MDSDGMTPLHLAAKWGYLEIVEVLLK 134 Score = 36.6 bits (83), Expect = 0.043, Method: Composition-based stats. Identities = 22/97 (22%), Positives = 40/97 (41%), Gaps = 15/97 (15%) Query: 290 ISNHQGLTPLKLAAKEGKIEIFRHILQREFSGPYQPLSRKFTEWCYGPVRVSLYDLSSVD 349 +++ G TPL LAA G +EI +L+ + + Y P+ ++ Y Sbjct: 42 AADNTGTTPLHLAAYSGHLEIVEVLLKHGADVDASDV------FGYTPLHLAAY------ 89 Query: 350 SWEKNSVLEIIAFHCKSPNRHRMVVLEPLNKLLQEKW 386 W ++E++ + N + PL+ L KW Sbjct: 90 -WGHLEIVEVLLKNGADVNAMDSDGMTPLH--LAAKW 123 >5H76-A nrPDB Length = 201 Score = 97.1 bits (240), Expect = 2e-20, Method: Composition-based stats. Identities = 39/165 (23%), Positives = 62/165 (37%), Gaps = 33/165 (20%) Query: 155 AQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPL 214 A G + LH+A L+ V++L+++GADV FG PL Sbjct: 30 ADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVDAS-------------DVFGYTPL 76 Query: 215 SLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGL 274 LAA ++V LL+N A + A DS G T LH + + + L Sbjct: 77 HLAAYWGHLEIVEVLLKNG---ADVNAMDSDGMTPLHLAAKWG---------YLEIVEVL 124 Query: 275 LQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQREF 319 L+ GA + G T ++ G ++ + + E Sbjct: 125 LKHGA--------VNAQDKFGKTAFDISIDNGNEDLAQILAFYEI 161 Score = 87.9 bits (216), Expect = 1e-17, Method: Composition-based stats. Identities = 40/146 (27%), Positives = 62/146 (42%), Gaps = 32/146 (21%) Query: 171 AIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLL 230 A V++L+ NGADV+ G PL LAA + ++V LL Sbjct: 13 AARAGQDDEVRILMANGADVNAADNT-------------GTTPLHLAAYSGHLEIVEVLL 59 Query: 231 ENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEI 290 ++ A ++A+D G T LH + + + LL+ GA + Sbjct: 60 KHG---ADVDASDVFGYTPLHLAAYWGH---------LEIVEVLLKNGADV-------NA 100 Query: 291 SNHQGLTPLKLAAKEGKIEIFRHILQ 316 + G+TPL LAAK G +EI +L+ Sbjct: 101 MDSDGMTPLHLAAKWGYLEIVEVLLK 126 >6MWQ-A nrPDB Length = 493 Score = 95.6 bits (236), Expect = 8e-20, Method: Composition-based stats. Identities = 45/204 (22%), Positives = 76/204 (37%), Gaps = 48/204 (23%) Query: 114 GSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIE 173 GK L A + G + + L+ D G + LH+A + Sbjct: 3 SDLGKKLLEAA----RAGQDDEVRILMANGADVNALDRF-----------GLTPLHLAAQ 47 Query: 174 KRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENP 233 + L+ V++L++ GADV+ +G+ PL LAA ++V LL+ Sbjct: 48 RGHLEIVEVLLKCGADVNAA-------------DLWGQTPLHLAATAGHLEIVEVLLKYG 94 Query: 234 HQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNH 293 A + A D +G T LH + + + + LL+ GA + + Sbjct: 95 ---ADVNALDLIGKTPLHLTAIDGH---------LEIVEVLLKHGADV-------NAQDK 135 Query: 294 QGLTPLKLAAKEGKIEIFRHILQR 317 G T ++ G E ILQ+ Sbjct: 136 FGKTAFDISIDNGN-EDLAEILQK 158 >5AQB-A nrPDB Length = 428 Score = 91.3 bits (225), Expect = 1e-18, Method: Composition-based stats. Identities = 40/156 (25%), Positives = 60/156 (38%), Gaps = 33/156 (21%) Query: 155 AQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPL 214 A G + LH+A L+ V+ L++NGADV+ G PL Sbjct: 38 ADVNALDEVGWTPLHLAAW-GHLEIVECLLKNGADVNAA-------------DIDGYTPL 83 Query: 215 SLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGL 274 LAA + ++V LL+ A + A D G T LH + + + + L Sbjct: 84 HLAAFSGHLEIVEVLLKYG---ADVNADDQAGFTPLHLAAIFGH---------LEIVEVL 131 Query: 275 LQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEI 310 L+ GA + + G TP LA G +I Sbjct: 132 LKNGADV-------NAQDKFGKTPRDLAIDNGNEDI 160 Score = 75.2 bits (183), Expect = 9e-14, Method: Composition-based stats. Identities = 39/146 (26%), Positives = 56/146 (38%), Gaps = 33/146 (22%) Query: 171 AIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLL 230 A ++L+ NGADV+ G PL LAA ++V LL Sbjct: 21 AARAGQDDECRILMANGADVNA-------------LDEVGWTPLHLAAW-GHLEIVECLL 66 Query: 231 ENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEI 290 +N A + A D G T LH + + + LL+ GA + Sbjct: 67 KNG---ADVNAADIDGYTPLHLAAFSGH---------LEIVEVLLKYGADVNAD------ 108 Query: 291 SNHQGLTPLKLAAKEGKIEIFRHILQ 316 + G TPL LAA G +EI +L+ Sbjct: 109 -DQAGFTPLHLAAIFGHLEIVEVLLK 133 Score = 57.4 bits (137), Expect = 2e-08, Method: Composition-based stats. Identities = 25/95 (26%), Positives = 39/95 (41%), Gaps = 13/95 (13%) Query: 155 AQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPL 214 A + G + LH+A L+ V++L++NGADV+ + FG+ P Sbjct: 103 ADVNADDQAGFTPLHLAAIFGHLEIVEVLLKNGADVNAQ-------------DKFGKTPR 149 Query: 215 SLAACTKQWDVVTYLLENPHQPASLEATDSLGNTV 249 LA D+ L + +A D LG V Sbjct: 150 DLAIDNGNEDIAEVLGKAATLVKVKDAADQLGARV 184 >6CUD-A nrPDB Length = 806 Score = 89.0 bits (219), Expect = 6e-18, Method: Composition-based stats. Identities = 45/270 (16%), Positives = 103/270 (38%), Gaps = 64/270 (23%) Query: 439 ILILLGGIYLLLGQLWY-FWRRRLFIWISFMDSYFEILF----------LLQAL------ 481 ++ +LG ++ +LW R + + +D +F LQA Sbjct: 430 MVWVLGMMWSECKELWLEGPREYILQLWNVLDFGMLSIFIAAFTARFLAFLQATKAQQYV 489 Query: 482 -----------LTVLSQVLRFM-ETEWYLP---------LLVLSLVLGWLNLLYYTRGFQ 520 +T+ ++ F + +LP L +++VL + + Y + Sbjct: 490 DSYVQESDLSEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSRIAYILPANE 549 Query: 521 HTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVSLSREARSPKAPEDNNSTVTEQPT 580 G + + + + +D+ +F++++++ F F + + L K Sbjct: 550 SFGPLQISLGRTV-KDIFKFMVLFIMVFFAFMIGMFILYSYYLGAKV------------- 595 Query: 581 VGQEEEPAPYRSILDASLELFKFTIGMGELAFQEQLRFRGVVL-----LLLLAYVLLTYV 635 A + ++ ++ LF G+ E+ L++ + +L Y + V Sbjct: 596 ------NAAFTTVEESFKTLFWSIFGLSEVT-SVVLKYDHKFIENIGYVLYGIYNVTMVV 648 Query: 636 LLLNMLIALMSETVNHVADNSWSIWKLQKA 665 +LLNMLIA+++ + + D+S WK ++ Sbjct: 649 VLLNMLIAMINSSYQEIEDDSDVEWKFARS 678 Score = 30.1 bits (66), Expect = 4.2, Method: Composition-based stats. Identities = 20/88 (22%), Positives = 31/88 (35%), Gaps = 18/88 (20%) Query: 157 CTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSL 216 Y G +AL +A+ L+ +LL++ +L G L L Sbjct: 55 VNCVDYMGQNALQLAVGNEHLEVTELLLKKE---NLARIGDA---------------LLL 96 Query: 217 AACTKQWDVVTYLLENPHQPASLEATDS 244 A +V +L +P AS T S Sbjct: 97 AISKGYVRIVEAILNHPGFAASKRLTLS 124 >5MIO-C nrPDB Length = 573 Score = 85.2 bits (209), Expect = 1e-16, Method: Composition-based stats. Identities = 38/163 (23%), Positives = 63/163 (38%), Gaps = 33/163 (20%) Query: 155 AQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPL 214 A G + LH+A L+ V++L+++GADV G PL Sbjct: 434 ADVNATDASGLTPLHLAATYGHLEIVEVLLKHGADVSAS-------------DLMGSTPL 480 Query: 215 SLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGL 274 LAA ++V LL++ A + A D+ G+T L ++ + + + L Sbjct: 481 HLAALIGHLEIVEVLLKHG---ADVNAVDTWGDTPLRLAAVMGH---------LKIVEAL 528 Query: 275 LQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQR 317 L+ GA + + G T + G E ILQ+ Sbjct: 529 LKHGADV-------NAQDKFGKTAYDTSIDNGS-EDLAEILQK 563 Score = 84.4 bits (207), Expect = 2e-16, Method: Composition-based stats. Identities = 45/184 (24%), Positives = 75/184 (40%), Gaps = 44/184 (23%) Query: 171 AIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLL 230 A V++L+ NGADV+ G PL LAA ++V LL Sbjct: 417 AARAGQDDEVRVLMANGADVNATDAS-------------GLTPLHLAATYGHLEIVEVLL 463 Query: 231 ENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEI 290 ++ A + A+D +G+T LH +I + + + LL+ GA + Sbjct: 464 KHG---ADVSASDLMGSTPLHLAALIGH---------LEIVEVLLKHGADV-------NA 504 Query: 291 SNHQGLTPLKLAAKEGKIEIFRHILQREFSGPYQPLSRKFTEWCYGPVRVSLYDLSSVDS 350 + G TPL+LAA G ++I +L+ G KF + Y +S+D+ Sbjct: 505 VDTWGDTPLRLAAVMGHLKIVEALLK---HGADVNAQDKFGKTAYD---------TSIDN 552 Query: 351 WEKN 354 ++ Sbjct: 553 GSED 556 >6CV9-A nrPDB Length = 842 Score = 84.0 bits (206), Expect = 2e-16, Method: Composition-based stats. Identities = 45/300 (15%), Positives = 106/300 (35%), Gaps = 73/300 (24%) Query: 442 LLGGIYLLLGQLW-YFWRRRLFIWISFMDSYFEILFLLQAL------------------- 481 ++G I+ ++W + LF + +D +F + Sbjct: 413 VIGMIWAECKEIWTQGPKEYLFELWNMLDFGMLAIFAASFIARFMAFWHASKAQSIIDAN 472 Query: 482 --LTVLSQVLRFMETEWYL----------PLLVLSLVLGWLNLLYYTR------GFQHTG 523 L L++V ++Y P ++ + +L ++R + G Sbjct: 473 DTLKDLTKVTLGDNVKYYNLARIKWDPTDPQIISEGLYAIAVVLSFSRIAYILPANESFG 532 Query: 524 IYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVSLSREARSPKAPEDNNSTVTEQPTVGQ 583 + + + + +D+ +F++++++ F + + +L K Sbjct: 533 PLQISLGRTV-KDIFKFMVIFIMVFVAFMIGMFNLYSYYIGAK----------------- 574 Query: 584 EEEPAPYRSILDASLELFKFTIGMGELA---FQEQLRFR-GVVLLLLLAYVLLTYVLLLN 639 + + ++ ++ LF G+ E+ +F + +L Y + ++LLN Sbjct: 575 --QNEAFTTVEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGYVLYGVYNVTMVIVLLN 632 Query: 640 MLIALMSETVNHVADNSWSIWKLQKAISVLEMENGYWWCRRKKHREGRLLKVGTRGDGTP 699 MLIA+++ + + D++ WK +A W+ EGR L V +P Sbjct: 633 MLIAMINSSFQEIEDDADVEWKFARA--------KLWF---SYFEEGRTLPVPFNLVPSP 681 Score = 32.0 bits (71), Expect = 1.1, Method: Composition-based stats. Identities = 8/38 (21%), Positives = 17/38 (44%) Query: 149 PKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVEN 186 + + Y G +AL +A+ L+ +LL++ Sbjct: 29 LEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKK 66 >5CBO-A nrPDB Length = 176 Score = 76.7 bits (187), Expect = 3e-14, Method: Composition-based stats. Identities = 32/137 (23%), Positives = 52/137 (37%), Gaps = 32/137 (23%) Query: 171 AIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLL 230 A V++L+ NGADV+ FG PL LAA +++V LL Sbjct: 10 AAHAGQDDEVRILMANGADVNA-------------MDNFGVTPLHLAAYWGHFEIVEVLL 56 Query: 231 ENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEI 290 + A + A+D+ G+T LH + + + LL+ GA + Sbjct: 57 KYG---ADVNASDATGDTPLHLAAKWG---------YLGIVEVLLKYGADV-------NA 97 Query: 291 SNHQGLTPLKLAAKEGK 307 + G T ++ G Sbjct: 98 QDKFGKTAFDISIDNGN 114 Score = 65.9 bits (159), Expect = 7e-11, Method: Composition-based stats. Identities = 33/164 (20%), Positives = 53/164 (32%), Gaps = 40/164 (24%) Query: 114 GSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIE 173 GK L A G + + L+ D G + LH+A Sbjct: 1 SDLGKKLLEAA----HAGQDDEVRILMANGADVNAMDNF-----------GVTPLHLAAY 45 Query: 174 KRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENP 233 + V++L++ GADV+ G+ PL LAA +V LL+ Sbjct: 46 WGHFEIVEVLLKYGADVNAS-------------DATGDTPLHLAAKWGYLGIVEVLLKYG 92 Query: 234 HQPASLEATDSLGNTVLHALV---------MIADNSPENSALVI 268 A + A D G T + ++ N + +A Sbjct: 93 ---ADVNAQDKFGKTAFDISIDNGNEDLAEILCKNKAQQAAFYC 133 Score = 55.1 bits (131), Expect = 1e-07, Method: Composition-based stats. Identities = 30/100 (30%), Positives = 41/100 (41%), Gaps = 19/100 (19%) Query: 217 AACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQ 276 AA Q D V L+ N A + A D+ G T LH + + LL+ Sbjct: 10 AAHAGQDDEVRILMANG---ADVNAMDNFGVTPLHLAAYWGHF---------EIVEVLLK 57 Query: 277 MGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQ 316 GA + S+ G TPL LAAK G + I +L+ Sbjct: 58 YGADVN-------ASDATGDTPLHLAAKWGYLGIVEVLLK 90 >4OAU-C nrPDB Length = 699 Score = 72.1 bits (175), Expect = 8e-13, Method: Composition-based stats. Identities = 55/228 (24%), Positives = 94/228 (41%), Gaps = 38/228 (16%) Query: 111 YTEGSTGKTCLMKAV---------LNLQDGVNACIM--------PLLQIDKDSGNPKLLV 153 + E G T L AV L L+ G + + L I KL + Sbjct: 33 FQEEEGGWTPLHNAVQMSREDIVELLLRHGADPVLRKKNGATPFILAAIAGSVKLLKLFL 92 Query: 154 N--AQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGE 211 + A + + G +A A ++ +K L + GA+V+LR R ++ Q G Sbjct: 93 SKGADVNECDFYGFTAFMEAAVYGKVKALKFLYKRGANVNLR---RKTKEDQERLRKGGA 149 Query: 212 LPLSLAACTKQWDVVTYLLENPHQPASLEATDSLG-NTVLHALVMIADNSPENSALVIHM 270 L AA +V+ LL+ A + A D++G N ++HAL+ D+ E + Sbjct: 150 TALMDAAEKGHVEVLKILLD--EMGADVNACDNMGRNALIHALLSSDDSDVE------AI 201 Query: 271 YDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQRE 318 LL GA + + +G TPL LA ++ + + + +L++E Sbjct: 202 THLLLDHGADV-------NVRGERGKTPLILAVEKKHLGLVQRLLEQE 242 Score = 51.3 bits (121), Expect = 2e-06, Method: Composition-based stats. Identities = 34/159 (21%), Positives = 61/159 (38%), Gaps = 31/159 (19%) Query: 171 AIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLL 230 A++ + V+ L+E GA+V+ FQ+ +G G PL A + D+V LL Sbjct: 12 AVQNEDVDLVQQLLEGGANVN-------FQEEEG-----GWTPLHNAVQMSREDIVELLL 59 Query: 231 ENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEI 290 + A G T L IA + + + L GA + Sbjct: 60 RHG---ADPVLRKKNGATPF-ILAAIAGS--------VKLLKLFLSKGADVNEC------ 101 Query: 291 SNHQGLTPLKLAAKEGKIEIFRHILQREFSGPYQPLSRK 329 + G T AA GK++ + + +R + + +++ Sbjct: 102 -DFYGFTAFMEAAVYGKVKALKFLYKRGANVNLRRKTKE 139 Score = 49.7 bits (117), Expect = 5e-06, Method: Composition-based stats. Identities = 48/238 (20%), Positives = 78/238 (32%), Gaps = 51/238 (21%) Query: 100 RWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTD 159 +G G T LM A + G + LL + A Sbjct: 133 LRRKTKEDQERLRKG--GATALMDAA---EKGHVEVLKILLDE----------MGADVNA 177 Query: 160 EFYQGHSALHIAIEKRSLQCVK----LLVENGADVHLRACGRFFQKHQGTCFYFGELPLS 215 G +AL A+ V+ LL+++GADV++R G+ PL Sbjct: 178 CDNMGRNALIHALLSSDDSDVEAITHLLLDHGADVNVRG-------------ERGKTPLI 224 Query: 216 LAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLL 275 LA K +V LLE H + TDS G T L V + + + + L Sbjct: 225 LAVEKKHLGLVQRLLEQEH--IEINDTDSDGKTALLLAVELK---------LKKIAELLC 273 Query: 276 QMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQREFSGPYQPLSRKFTEW 333 + GA + + + +K + H + +F P + + + W Sbjct: 274 KRGASTDCGDLVMTARRNYDHSLVK--------VLLSHGAKEDFHPPAEDWKPQSSHW 323 Score = 38.9 bits (89), Expect = 0.009, Method: Composition-based stats. Identities = 25/108 (23%), Positives = 40/108 (37%), Gaps = 19/108 (17%) Query: 80 LFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDG-VNACIMP 138 L +G E L LL+ + + G+ L+ A+L+ D V A Sbjct: 152 LMDAAEKGHVEVLKILLDEM-------GADVNACDNMGRNALIHALLSSDDSDVEAITHL 204 Query: 139 LLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVEN 186 LL A +G + L +A+EK+ L V+ L+E Sbjct: 205 LLDHG-----------ADVNVRGERGKTPLILAVEKKHLGLVQRLLEQ 241 Score = 33.9 bits (76), Expect = 0.24, Method: Composition-based stats. Identities = 26/143 (18%), Positives = 49/143 (34%), Gaps = 20/143 (13%) Query: 66 APSQQEPDRFDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAV 125 D R+ L + ++ + L + + G GKT L+ AV Sbjct: 172 GADVNACDNMGRNALIHALLSSDDSDVEAITHLLLDHGADVN----VRGERGKTPLILAV 227 Query: 126 LNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVE 185 G+ + LL+ + + + D G +AL +A+E + + +LL + Sbjct: 228 EKKHLGL---VQRLLEQE----------HIEINDTDSDGKTALLLAVELKLKKIAELLCK 274 Query: 186 NGADVHLRACGRFFQKHQGTCFY 208 GA CG + + Sbjct: 275 RGASTD---CGDLVMTARRNYDH 294 >6BWF-A nrPDB Length = 954 Score = 68.2 bits (165), Expect = 1e-11, Method: Composition-based stats. Identities = 53/337 (15%), Positives = 116/337 (34%), Gaps = 62/337 (18%) Query: 348 VDSWEKNSVLEIIAFHCKSPNRHRMVVLEPLNKLLQEKWDRLVSRFFFNFACYLVYMFIF 407 +DS + + +EI K P+ + + + +F+FN YL ++ ++ Sbjct: 475 LDSSDGKNEMEIHIKSKKL----------PITRKFYAFYHAPIVKFWFNTLAYLGFLMLY 524 Query: 408 TVVAYHQPSLDQPAIPS---SKATFGESMLLLGHILILLGGIYLLLGQLWY--------- 455 T V + P++ F ++ + + + G ++W+ Sbjct: 525 TFVVLVK-MEQLPSVQEWIVIAYIFTYAIEKVREVFMSEAGKISQKIKVWFSDYFNVSDT 583 Query: 456 --------FWRRRLFIWISFMDSYFEILFLLQALLTVLSQVLRFMETEWYLPLLVLSLVL 507 + R +++++Y +F+ L+ L+ + WY+ LL V Sbjct: 584 IAIISFFVGFGLRFGAKWNYINAYDNHVFVAGRLIYCLNIIF------WYVRLLDFLAV- 636 Query: 508 GWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVSLSREARSPKA 567 Q G Y +MI K++ ++ +++ + L F V ++ P Sbjct: 637 -----------NQQAGPYVMMIGKMV-ANMFYIVVIMALVLLSFGVPRKAILYPHEEPSW 684 Query: 568 PEDNNSTVTEQPTVGQEEEPAPYRSILDASLELFKFTIGMGELAFQEQLRFRGVVLLLLL 627 + + E Y +D G + + L Sbjct: 685 SLAKDIVFHPYWMIFGE----VYAYEIDVCANDSTLPTICGPGTW--------LTPFLQA 732 Query: 628 AYVLLTYVLLLNMLIALMSETVNHVADNSWSIWKLQK 664 Y+ + Y++++N+LIA + V S +WK Q+ Sbjct: 733 VYLFVQYIIMVNLLIAFFNNVYLQVKAISNIVWKYQR 769 >5GP7-A nrPDB Length = 169 Score = 66.7 bits (161), Expect = 4e-11, Method: Composition-based stats. Identities = 38/149 (25%), Positives = 56/149 (37%), Gaps = 32/149 (21%) Query: 154 NAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELP 213 N C D + + LH+A +L+ + L+E+GADV+ + G G +P Sbjct: 33 NINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKG-------------GLIP 79 Query: 214 LSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDG 273 L AA D+ L++ + ATD T LH + Sbjct: 80 LHNAASYGHVDIAALLIKYN---TCVNATDKWAFTPLHEAAQKGR---------TQLCAL 127 Query: 274 LLQMGARLCPTVQLEEISNHQGLTPLKLA 302 LL GA + N +G TPL LA Sbjct: 128 LLAHGAD-------PTMKNQEGQTPLDLA 149 Score = 35.1 bits (79), Expect = 0.12, Method: Composition-based stats. Identities = 28/139 (20%), Positives = 49/139 (35%), Gaps = 28/139 (20%) Query: 203 QGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLG--NTVLHALVMIADNS 260 G+ G+ L AA V L P ++ D+ G +T LH + Sbjct: 2 PGSDLLRGDAALLDAAKKGCLARVQKLC----TPENINCRDTQGRNSTPLHLAAGYNN-- 55 Query: 261 PENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQREFS 320 + + + LL+ GA + + GL PL AA G ++I +++ Sbjct: 56 -------LEVAEYLLEHGADVN-------AQDKGGLIPLHNAASYGHVDIAALLIK---- 97 Query: 321 GPYQPLSRKFTEWCYGPVR 339 Y +W + P+ Sbjct: 98 --YNTCVNATDKWAFTPLH 114 >6BPQ-A nrPDB Length = 950 Score = 64.8 bits (156), Expect = 1e-10, Method: Composition-based stats. Identities = 58/301 (19%), Positives = 112/301 (37%), Gaps = 31/301 (10%) Query: 375 LEPLNKLLQEKWDRLVSRFFFNFACYLVYMFIFTVVAYHQPSLDQPAIPSSKATFGESML 434 +E KL S F + Y+ + AY Q + + Sbjct: 592 VEKTKKLFLYYVSFFTSPFVVFSWNVIFYIAFLLLFAYVLLMDFQKEPTALEI------- 644 Query: 435 LLGHILILLGGIYL--LLGQLWYFWRRRLFIWISFMDSYFEILFLLQALLTVLSQVLRFM 492 IL +L I L + Q + + + MD+ F+ + + S Sbjct: 645 ----ILYVLVFILLCDEVRQWYMNGSKYFSDLWNVMDTLAIFYFIAGIVFRLHSD----- 695 Query: 493 ETEWYLPLLVLSL-----VLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVF 547 E+ WY ++ L L +++ +R + G +M+Q++++ D+ FL ++ V+ Sbjct: 696 ESSWYSGRVIFCLDYIVFTLRLIHIFTVSR---NLGPKIIMLQRMMI-DVFFFLFLFAVW 751 Query: 548 LFGFAVALVSLSREARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDASLELFK---FT 604 + F VA + R+ + + + + + F Sbjct: 752 MVAFGVARQGILRKNEHRWEWIFRSVIYEPYLAMFGQYPDDIDGTTYNFDHCTFSGNESK 811 Query: 605 IGMGELAFQEQLRFRG-VVLLLLLAYVLLTYVLLLNMLIALMSETVNHVADNSWSIWKLQ 663 EL Q RF + + L+ Y+L T +LL+N+L+A+ TV V +N+ +WK Q Sbjct: 812 PLCVELDANNQPRFPEWITIPLVCIYMLSTNILLVNLLVAMFGYTVGSVQENNDQVWKFQ 871 Query: 664 K 664 + Sbjct: 872 R 872 >5JHQ-A nrPDB Length = 482 Score = 62.1 bits (149), Expect = 8e-10, Method: Composition-based stats. Identities = 46/201 (22%), Positives = 68/201 (33%), Gaps = 37/201 (18%) Query: 130 DGVNACIMPLLQIDKDSGNPKL-----LVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLV 184 V+ + LL+ ++ ++ N D + S LH A V+ L+ Sbjct: 10 PAVSGALRELLEACRNGDVSRVKRLVDAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLL 69 Query: 185 ENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDS 244 + GA+VH R G G +PL A +VV+ LL Q A A D+ Sbjct: 70 QMGANVHARDDG-------------GLIPLHNACSFGHAEVVSLLL---CQGADPNARDN 113 Query: 245 LGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAK 304 T LH + I + LLQ GA I N G + L LA Sbjct: 114 WNYTPLHEAAIKGK---------IDVCIVLLQHGAD-------PNIRNTDGKSALDLADP 157 Query: 305 EGKIEIFRHILQREFSGPYQP 325 K + + E + Sbjct: 158 SAKAVLTGEYKKDELLEAARS 178 Score = 60.5 bits (145), Expect = 3e-09, Method: Composition-based stats. Identities = 41/170 (24%), Positives = 67/170 (39%), Gaps = 37/170 (21%) Query: 123 KAVLNLQDGVNACIMP-------LLQIDKDSGNPKLLV-----NAQCTDEFYQGHSALHI 170 K+ L+L D ++ LL+ + KL+ N C + + LH+ Sbjct: 149 KSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHL 208 Query: 171 AIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLL 230 A ++ V+LL+++GADVH + G G +PL A ++V LL Sbjct: 209 AAGYNRVRIVQLLLQHGADVHAKDKG-------------GLVPLHNACSYGHYEVTELLL 255 Query: 231 ENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGAR 280 ++ A + A D T LH + + +N V LL GA Sbjct: 256 KHG---ACVNAMDLWQFTPLH------EAASKNRVEVCS---LLLSHGAD 293 Score = 54.0 bits (128), Expect = 2e-07, Method: Composition-based stats. Identities = 22/132 (16%), Positives = 43/132 (32%), Gaps = 24/132 (18%) Query: 111 YTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHI 170 + + + +T L AV +L LL+ A ++ + LH+ Sbjct: 349 FKQPQSHETALHCAVASLHPKRKQVTELLLRKG-----------ANVNEKNKDFMTPLHV 397 Query: 171 AIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLL 230 A E+ +++L ++GA ++ G+ L AA LL Sbjct: 398 AAERAHNDVMEVLHKHGAKMNA-------------LDTLGQTALHRAALAGHLQTCRLLL 444 Query: 231 ENPHQPASLEAT 242 P+ + Sbjct: 445 SYGSDPSIISLQ 456 Score = 49.3 bits (116), Expect = 6e-06, Method: Composition-based stats. Identities = 38/155 (24%), Positives = 57/155 (36%), Gaps = 40/155 (25%) Query: 165 HSALHIAIEKRS---LQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTK 221 +ALH A+ Q +LL+ GA+V+ + PL +AA Sbjct: 356 ETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFM-------------TPLHVAAERA 402 Query: 222 QWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARL 281 DV+ L ++ A + A D+LG T LH + + LL G+ Sbjct: 403 HNDVMEVLHKHG---AKMNALDTLGQTALHRAALAGH---------LQTCRLLLSYGSD- 449 Query: 282 CPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQ 316 I + QG T AA+ G E + IL Sbjct: 450 ------PSIISLQGFT----AAQMGN-EAVQQILS 473 Score = 47.8 bits (112), Expect = 2e-05, Method: Composition-based stats. Identities = 38/200 (19%), Positives = 64/200 (32%), Gaps = 33/200 (16%) Query: 148 NPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRAC--------GRFF 199 + L A ++ LH A K + +L+++GAD ++R Sbjct: 99 SLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPS 158 Query: 200 QKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADN 259 K T Y + L A + ++ L + A+D +T LH Sbjct: 159 AKAVLTGEYKKDELLEAARSGNEEKLMALLT---PLNVNCHASDGRKSTPLHLAAGYNR- 214 Query: 260 SPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQREF 319 + + LLQ GA + + GL PL A G E+ +L+ Sbjct: 215 --------VRIVQLLLQHGADVH-------AKDKGGLVPLHNACSYGHYEVTELLLKHGA 259 Query: 320 SGPYQPLSRKFTEWCYGPVR 339 L W + P+ Sbjct: 260 CVNAMDL------WQFTPLH 273 >2DWZ-A nrPDB Length = 231 Score = 62.1 bits (149), Expect = 1e-09, Method: Composition-based stats. Identities = 44/178 (24%), Positives = 63/178 (35%), Gaps = 41/178 (23%) Query: 156 QCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLS 215 D+ G S LHIA + VK L+ GA V+ +Q C PL Sbjct: 65 PVNDKDDAGWSPLHIAASAGRDEIVKALLVKGAHVNAV--------NQNGC-----TPLH 111 Query: 216 LAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLL 275 AA + ++ LLE P +A D T +H + + M LL Sbjct: 112 YAASKNRHEIAVMLLEGGANP---DAKDHYDATAMHRAAAKGN---------LKMVHILL 159 Query: 276 QMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFR---------HILQREFSGPYQ 324 A I + +G TPL LA E ++E + +I +E P Q Sbjct: 160 FYKAS-------TNIQDTEGNTPLHLACDEERVEEAKFLVTQGASIYIENKEEKTPLQ 210 Score = 57.1 bits (136), Expect = 3e-08, Method: Composition-based stats. Identities = 47/232 (20%), Positives = 75/232 (32%), Gaps = 51/232 (21%) Query: 87 GVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDS 146 T ++E+L + D G + L A G + + LL Sbjct: 47 ACSAGHTEIVEFLLQLGVPVNDKD----DAGWSPLHIAA---SAGRDEIVKALL------ 93 Query: 147 GNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTC 206 + A G + LH A K + +L+E GA+ Sbjct: 94 -----VKGAHVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGAN-------------PDAK 135 Query: 207 FYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSAL 266 ++ + AA +V LL AS D+ GNT LH + E + Sbjct: 136 DHYDATAMHRAAAKGNLKMVHILL---FYKASTNIQDTEGNTPLHLAC--DEERVEEAKF 190 Query: 267 VIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQRE 318 L+ GA + I N + TPL++A K G I + + + E Sbjct: 191 -------LVTQGASIY-------IENKEEKTPLQVA-KGGLGLILKRLAEGE 227 Score = 42.8 bits (99), Expect = 6e-04, Method: Composition-based stats. Identities = 23/105 (21%), Positives = 36/105 (34%), Gaps = 19/105 (18%) Query: 212 LPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMY 271 L A ++V +LL+ + D G + LH + + Sbjct: 42 TALHWACSAGHTEIVEFLLQ---LGVPVNDKDDAGWSPLHIAASAGRD---------EIV 89 Query: 272 DGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQ 316 LL GA + N G TPL AA + + EI +L+ Sbjct: 90 KALLVKGAHV-------NAVNQNGCTPLHYAASKNRHEIAVMLLE 127 >4NIK-A nrPDB Length = 230 Score = 61.3 bits (147), Expect = 1e-09, Method: Composition-based stats. Identities = 44/178 (24%), Positives = 63/178 (35%), Gaps = 41/178 (23%) Query: 156 QCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLS 215 D+ G S LHIA + VK L+ GA V+ +Q C PL Sbjct: 69 PVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAV--------NQNGC-----TPLH 115 Query: 216 LAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLL 275 AA + ++ LLE P +A D T +H + + M LL Sbjct: 116 YAASKNRHEIAVMLLEGGANP---DAKDHYEATAMHRAAAKGN---------LKMIHILL 163 Query: 276 QMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFR---------HILQREFSGPYQ 324 A I + +G TPL LA E ++E + +I +E P Q Sbjct: 164 YYKAS-------TNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQ 214 Score = 56.3 bits (134), Expect = 5e-08, Method: Composition-based stats. Identities = 51/258 (19%), Positives = 84/258 (32%), Gaps = 52/258 (20%) Query: 59 RPPKNTSAPSQQEPDRFDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGK 118 K + + R D+D + + T ++E+L + D G Sbjct: 24 EELKESILADKSLATRTDQDSR-TALHWACSAGHTEIVEFLLQLGVPVNDKD----DAGW 78 Query: 119 TCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQ 178 + L A G + + LL AQ G + LH A K + Sbjct: 79 SPLHIAA---SAGRDEIVKALLGKG-----------AQVNAVNQNGCTPLHYAASKNRHE 124 Query: 179 CVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPAS 238 +L+E GA+ ++ + AA ++ LL + AS Sbjct: 125 IAVMLLEGGAN-------------PDAKDHYEATAMHRAAAKGNLKMIHILL---YYKAS 168 Query: 239 LEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTP 298 D+ GNT LH D A L+ GA + I N + TP Sbjct: 169 TNIQDTEGNTPLHLA---CDEERVEEA------KLLVSQGASIY-------IENKEEKTP 212 Query: 299 LKLAAKEGKIEIFRHILQ 316 L++A K G I + +++ Sbjct: 213 LQVA-KGGLGLILKRMVE 229 >5HKP-A nrPDB Length = 351 Score = 61.3 bits (147), Expect = 2e-09, Method: Composition-based stats. Identities = 45/178 (25%), Positives = 70/178 (39%), Gaps = 40/178 (22%) Query: 114 GSTGKTCL------MKAVLNLQDGVNACIMPLLQIDKDSGNPKLLV-----NAQCTDEFY 162 G GK+ L KAVL + + LL+ + KL+ N C Sbjct: 1 GEFGKSALDLADPSAKAVLTGEYKKDE----LLEAARSGNEEKLMALLTPLNVNCHASDG 56 Query: 163 QGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQ 222 + + LH+A ++ V+LL+++GADVH + G G +PL A Sbjct: 57 RKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKG-------------GLVPLHNACSYGH 103 Query: 223 WDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGAR 280 ++V LL++ A + A D T LH + + +N V LL GA Sbjct: 104 YEVTELLLKHG---ACVNAMDLWQFTPLH------EAASKNRVEVCS---LLLSHGAD 149 Score = 53.6 bits (127), Expect = 3e-07, Method: Composition-based stats. Identities = 22/132 (16%), Positives = 43/132 (32%), Gaps = 24/132 (18%) Query: 111 YTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHI 170 + + + +T L AV +L LL+ A ++ + LH+ Sbjct: 205 FKQPQSHETALHCAVASLHPKRKQVAELLLRKG-----------ANVNEKNKDFMTPLHV 253 Query: 171 AIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLL 230 A E+ +++L ++GA ++ G+ L AA LL Sbjct: 254 AAERAHNDVMEVLHKHGAKMNA-------------LDSLGQTALHRAALAGHLQTCRLLL 300 Query: 231 ENPHQPASLEAT 242 P+ + Sbjct: 301 SYGSDPSIISLQ 312 Score = 50.5 bits (119), Expect = 3e-06, Method: Composition-based stats. Identities = 39/155 (25%), Positives = 57/155 (36%), Gaps = 40/155 (25%) Query: 165 HSALHIAIEKRS---LQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTK 221 +ALH A+ Q +LL+ GA+V+ + PL +AA Sbjct: 212 ETALHCAVASLHPKRKQVAELLLRKGANVNEKNKDFM-------------TPLHVAAERA 258 Query: 222 QWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARL 281 DV+ L ++ A + A DSLG T LH + + LL G+ Sbjct: 259 HNDVMEVLHKHG---AKMNALDSLGQTALHRAALAGH---------LQTCRLLLSYGSD- 305 Query: 282 CPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQ 316 I + QG T AA+ G E + IL Sbjct: 306 ------PSIISLQGFT----AAQMGN-EAVQQILS 329 >4Z68-A nrPDB Length = 155 Score = 60.5 bits (145), Expect = 3e-09, Method: Composition-based stats. Identities = 40/154 (25%), Positives = 59/154 (38%), Gaps = 33/154 (21%) Query: 157 CTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSL 216 C D + + LH A + V+ L+++GADVH + G G +PL Sbjct: 30 CRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKG-------------GLVPLHN 76 Query: 217 AACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQ 276 A ++V L+++ A + D T LH + LLQ Sbjct: 77 ACSYGHYEVAELLVKHG---AVVNVADLWKFTPLHEAAAKGKY---------EICKLLLQ 124 Query: 277 MGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEI 310 GA PT + N G TPL L K+G +I Sbjct: 125 HGAD--PTKK-----NRDGNTPLDLV-KDGDTDI 150 Score = 49.7 bits (117), Expect = 5e-06, Method: Composition-based stats. Identities = 29/105 (27%), Positives = 44/105 (41%), Gaps = 19/105 (18%) Query: 212 LPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMY 271 PL AA + VV YLL++ A + A D G LH + Sbjct: 39 TPLHFAAGYNRVSVVEYLLQHG---ADVHAKDKGGLVPLHNACSYGHY---------EVA 86 Query: 272 DGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQ 316 + L++ GA + +++ TPL AA +GK EI + +LQ Sbjct: 87 ELLVKHGAVVN-------VADLWKFTPLHEAAAKGKYEICKLLLQ 124 Score = 46.3 bits (108), Expect = 5e-05, Method: Composition-based stats. Identities = 23/96 (23%), Positives = 38/96 (39%), Gaps = 16/96 (16%) Query: 155 AQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPL 214 A + G LH A + +LLV++GA V++ +F PL Sbjct: 61 ADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKF-------------TPL 107 Query: 215 SLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVL 250 AA ++++ LL++ A + GNT L Sbjct: 108 HEAAAKGKYEICKLLLQHG---ADPTKKNRDGNTPL 140 >6AUN-A nrPDB Length = 752 Score = 59.0 bits (141), Expect = 8e-09, Method: Composition-based stats. Identities = 54/254 (21%), Positives = 91/254 (35%), Gaps = 63/254 (24%) Query: 83 VVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQI 142 +G E L L++Y +TD+ G+T AV G N+ ++ LL Sbjct: 159 ACRKGDSEILVELVQYCHAQ-MDVTDNK------GETAFHYAV----QGDNSQVLQLLGK 207 Query: 143 DKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRF---- 198 + +G QG + LH+A + + V++L+ A ++ F Sbjct: 208 NASAG---------LNQVNKQGLTPLHLACQMGKQEMVRVLLLCNARCNVMGPSGFPIHT 258 Query: 199 -FQKHQGTCFY----------------FGELPLSLAACTKQWDVVTYLLENPHQPASLEA 241 + Q C +G PL A K ++ LL+ + +++ Sbjct: 259 AMKFSQKGCAEMIISMDSSQIHSKDPRYGASPLHWA---KNAEMARMLLK---RGCDVDS 312 Query: 242 TDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKL 301 T + GNT LH VM + M LL GA G TPL L Sbjct: 313 TSAAGNTALHVAVM-------RNRFDCVM--VLLTYGAN-------AGTPGEHGNTPLHL 356 Query: 302 AAKEGKIEIFRHIL 315 A + +E+ + ++ Sbjct: 357 AISKDNMEMIKALI 370 Score = 49.3 bits (116), Expect = 6e-06, Method: Composition-based stats. Identities = 27/112 (24%), Positives = 44/112 (39%), Gaps = 27/112 (24%) Query: 107 TDSAYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHS 166 + + G T L AV+ C+M LL ++G P G++ Sbjct: 307 GCDVDSTSAAGNTALHVAVMR---NRFDCVMVLLTYGANAGTPG-----------EHGNT 352 Query: 167 ALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAA 218 LH+AI K +++ +K L+ GA+V FGE P +A+ Sbjct: 353 PLHLAISKDNMEMIKALIVFGAEVDTPND-------------FGETPAFMAS 391 Score = 48.2 bits (113), Expect = 1e-05, Method: Composition-based stats. Identities = 32/106 (30%), Positives = 44/106 (41%), Gaps = 17/106 (16%) Query: 210 GELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIH 269 G PL LA +++ L++ H + TD+ G T H V DNS Sbjct: 152 GCTPLHLACRKGDSEILVELVQYCHAQMDV--TDNKGETAFHYAVQ-GDNSQ-------- 200 Query: 270 MYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHIL 315 L +G + N QGLTPL LA + GK E+ R +L Sbjct: 201 ---VLQLLGKNASAGLNQ---VNKQGLTPLHLACQMGKQEMVRVLL 240 Score = 37.8 bits (86), Expect = 0.017, Method: Composition-based stats. Identities = 28/108 (25%), Positives = 41/108 (37%), Gaps = 16/108 (14%) Query: 127 NLQDGVNACIMPLLQIDK-DSGNPKLLV---NAQCTDEFYQGHSALHIAIEKRSLQCVKL 182 N + C L K DS LV +AQ +G +A H A++ + Q ++L Sbjct: 145 NSTENEEGCTPLHLACRKGDSEILVELVQYCHAQMDVTDNKGETAFHYAVQGDNSQVLQL 204 Query: 183 LVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLL 230 L +N A K G PL LA + ++V LL Sbjct: 205 LGKN-----ASAGLNQVNKQ-------GLTPLHLACQMGKQEMVRVLL 240 Score = 37.0 bits (84), Expect = 0.031, Method: Composition-based stats. Identities = 25/130 (19%), Positives = 40/130 (30%), Gaps = 23/130 (17%) Query: 151 LLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFG 210 +++ + E +G + LH+A K + + LV+ + G Sbjct: 139 RIISCANSTENEEGCTPLHLACRKGDSEILVELVQ------------YCHAQMDVTDNKG 186 Query: 211 ELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHM 270 E A V+ L +N A L + G T LH + M Sbjct: 187 ETAFHYAVQGDNSQVLQLLGKNA--SAGLNQVNKQGLTPLHLACQMGKQ---------EM 235 Query: 271 YDGLLQMGAR 280 LL AR Sbjct: 236 VRVLLLCNAR 245 >5ET1-A nrPDB Length = 353 Score = 57.8 bits (138), Expect = 2e-08, Method: Composition-based stats. Identities = 50/224 (22%), Positives = 75/224 (33%), Gaps = 44/224 (19%) Query: 93 TGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKLL 152 TG L L+W + ++G T L A + LL + Sbjct: 81 TGYLSCLQWLLTQGGCRVQEKDNSGATVLHLAARFGHP---DVVKWLLY--------QGG 129 Query: 153 VNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGAD-VHLRACGRFFQKHQGTCFYFGE 211 N+ T + G +H A K L +KLLV + + V+ + G Sbjct: 130 ANSAITTD--TGALPIHYAAAKGDLPSLKLLVGHYPEGVNAQTNN-------------GA 174 Query: 212 LPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMY 271 PL LA +V YL++ L A D G T LHA + N Sbjct: 175 TPLYLACQEGHLEVTKYLVQECSADPHLRAQD--GMTPLHAAAQMGHNPVL--------- 223 Query: 272 DGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHIL 315 L A + + Q +H G T + AA G ++ +L Sbjct: 224 -VWLVSFADVSFSEQ-----DHDGATAMHFAASRGHTKVLSWLL 261 Score = 53.2 bits (126), Expect = 4e-07, Method: Composition-based stats. Identities = 51/234 (21%), Positives = 83/234 (35%), Gaps = 40/234 (17%) Query: 92 LTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKL 151 L L+ R + S + G G + L+D ++A + + Sbjct: 4 LEQALQAARRGDLDVLRSLHAAGLLGPS--------LRDSLDALPVHHAARSGKLHCLRY 55 Query: 152 LVNA---QCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFY 208 LV G + H A L C++ L+ G G Q+ + Sbjct: 56 LVEEVALPAVSRARNGATPAHDAAATGYLSCLQWLLTQG--------GCRVQEKDNS--- 104 Query: 209 FGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVI 268 G L LAA DVV +LL +++ TD+ G +H D P LV Sbjct: 105 -GATVLHLAARFGHPDVVKWLLYQGGANSAIT-TDT-GALPIHYAAAKGD-LPSLKLLVG 160 Query: 269 HMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQREFSGP 322 H +G+ + G TPL LA +EG +E+ ++++Q + P Sbjct: 161 HYPEGV--------------NAQTNNGATPLYLACQEGHLEVTKYLVQECSADP 200 Score = 48.6 bits (114), Expect = 1e-05, Method: Composition-based stats. Identities = 30/160 (18%), Positives = 46/160 (28%), Gaps = 29/160 (18%) Query: 157 CTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSL 216 ++ G + LH+A VK L+ G G LP+ Sbjct: 98 VQEKDNSGATVLHLAARFGHPDVVKWLLYQGGANSAITTDT------------GALPIHY 145 Query: 217 AACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQ 276 AA + L+ H P + A + G T L+ E V Sbjct: 146 AAAKGDLPSLKLLV--GHYPEGVNAQTNNGATPLYLA------CQEGHLEVTKYLVQECS 197 Query: 277 MGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQ 316 L G+TPL AA+ G + ++ Sbjct: 198 ADPHL---------RAQDGMTPLHAAAQMGHNPVLVWLVS 228 Score = 45.1 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 24/121 (19%), Positives = 44/121 (36%), Gaps = 22/121 (18%) Query: 133 NACIMPLLQIDKDSGNPKL-----LVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENG 187 + PL + NP L + +++ + G +A+H A + + + L+ +G Sbjct: 205 QDGMTPLHAAAQMGHNPVLVWLVSFADVSFSEQDHDGATAMHFAASRGHTKVLSWLLLHG 264 Query: 188 ADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGN 247 A++ +G PL AA + + L N A L+ D G Sbjct: 265 AEISQ--------------DLWGGTPLHDAAENGELECCQILAVNG---AGLDVRDHDGY 307 Query: 248 T 248 T Sbjct: 308 T 308 >3B7B-A nrPDB Length = 237 Score = 56.7 bits (135), Expect = 3e-08, Method: Composition-based stats. Identities = 55/262 (20%), Positives = 92/262 (35%), Gaps = 48/262 (18%) Query: 99 LRWNSKYLTDSAYTEGSTGKTC--LMKAVLNLQDGVNACIMPLLQIDKDS--GNPKLLVN 154 + +K A E C L++A N+ PL++ +++ K L+ Sbjct: 6 MEHQNKRSPLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIK 65 Query: 155 A--QCTDEFYQGHSALHIAIEKRSLQCVKLLVENGA-DVHLRACGRFFQKHQGTCFYFGE 211 A + +G + LH+A +K + V+ L+ NG DV+ + G G Sbjct: 66 AGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDG-------------GW 112 Query: 212 LPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMY 271 P+ A K D+V LL + + + D+ N LH + + Sbjct: 113 TPMIWATEYKHVDLVKLLLS---KGSDINIRDNEENICLHWAAFSG---------CVDIA 160 Query: 272 DGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQR---------EFSGP 322 + LL L N G +PL +AA+E + + L R E P Sbjct: 161 EILLAAKCDLH-------AVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETP 213 Query: 323 YQPLSRKFTEWCYGPVRVSLYD 344 Q S W + +L D Sbjct: 214 LQCASLNSQVWSALQMSKALQD 235 Score = 49.7 bits (117), Expect = 4e-06, Method: Composition-based stats. Identities = 33/161 (20%), Positives = 55/161 (34%), Gaps = 31/161 (19%) Query: 157 CTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSL 216 E S LH A E + +LV+ GA++ TC PL Sbjct: 4 FKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANI-------------DTCSEDQRTPLME 50 Query: 217 AACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQ 276 AA + V YL++ A ++ D+ G+T LH + LL Sbjct: 51 AAENNHLEAVKYLIK---AGALVDPKDAEGSTCLHLAA---------KKGHYEVVQYLLS 98 Query: 277 MGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQR 317 G + G TP+ A + +++ + +L + Sbjct: 99 NG------QMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSK 133 >1BD8-A nrPDB Length = 156 Score = 53.2 bits (126), Expect = 4e-07, Method: Composition-based stats. Identities = 42/177 (23%), Positives = 63/177 (35%), Gaps = 39/177 (22%) Query: 78 DRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIM 137 DRL +RG +E+ LL D+ GKT L + Sbjct: 4 DRLSGAAARGDVQEVRRLLH----RELVHPDALNR---FGKTALQVMMFG-------STA 49 Query: 138 PLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGR 197 L++ K +P + G S +H A L +K+LVE+GADV++ Sbjct: 50 IALELLKQGASP--------NVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVP---- 97 Query: 198 FFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALV 254 G LP+ LA VV++L + L D+ G T L + Sbjct: 98 ---------DGTGALPIHLAVQEGHTAVVSFL----AAESDLHRRDARGLTPLELAL 141 Score = 44.0 bits (102), Expect = 3e-04, Method: Composition-based stats. Identities = 35/157 (22%), Positives = 58/157 (36%), Gaps = 36/157 (22%) Query: 150 KLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYF 209 + LV+ + F G +AL + + S L++ GA +++ Sbjct: 24 RELVHPDALNRF--GKTALQV-MMFGSTAIALELLKQGASPNVQDTS------------- 67 Query: 210 GELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIH 269 G P+ AA T D + L+E+ A + D G +H V E V+ Sbjct: 68 GTSPVHDAARTGFLDTLKVLVEHG---ADVNVPDGTGALPIHLAV------QEGHTAVVS 118 Query: 270 MYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEG 306 L + L + +GLTPL+LA + G Sbjct: 119 ----FLAAESDLHR-------RDARGLTPLELALQRG 144 >4OT9-A nrPDB Length = 359 Score = 52.8 bits (125), Expect = 6e-07, Method: Composition-based stats. Identities = 59/282 (20%), Positives = 95/282 (33%), Gaps = 66/282 (23%) Query: 59 RPPKNTSAPS------QQEPDRFDRDR-----LFSVVSR--------GVPEELTGLLEYL 99 SAPS Q P+ R R LF + R GV + LL Sbjct: 12 EEAAEPSAPSRTPQCEPQAPEMLQRAREYNARLFGLAQRSARALLDYGVTADARALLAG- 70 Query: 100 RWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTD 159 + + D G T L A+++ Q V I+ ++ +D G L T+ Sbjct: 71 QRHLLTAQDE------NGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNL------TN 118 Query: 160 EFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLA-- 217 + + LH+A+ V L+ GAD G+ + LA Sbjct: 119 HLH--QTPLHLAVITGQTSVVSFLLRVGAD-------------PALLDRHGDSAMHLALR 163 Query: 218 ACTKQWDVVTYLLENPHQ--PASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLL 275 A +++ LL++ P L D G +H V A D L+ Sbjct: 164 AGAGAPELLRALLQSGAPAVPQLLHMPDFEGLYPVHLAV---------RARSPECLDLLV 214 Query: 276 QMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQR 317 GA ++E G T L LA + ++ + H++ + Sbjct: 215 DSGA------EVEATERQGGRTALHLATEMEELGLVTHLVTK 250 Score = 52.4 bits (124), Expect = 7e-07, Method: Composition-based stats. Identities = 46/183 (25%), Positives = 73/183 (39%), Gaps = 37/183 (20%) Query: 117 GKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRS 176 G + + A L G + LLQ P+LL ++G +H+A+ RS Sbjct: 154 GDSAMHLA-LRAGAGAPELLRALLQ-SGAPAVPQLLHMPD-----FEGLYPVHLAVRARS 206 Query: 177 LQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQP 236 +C+ LLV++GA+V + QG G L LA ++ +VT+L+ Sbjct: 207 PECLDLLVDSGAEVEA-------TERQG-----GRTALHLATEMEELGLVTHLV--TKLR 252 Query: 237 ASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGL 296 A++ A GNT LH + + LL+ GA + N + L Sbjct: 253 ANVNARTFAGNTPLHLAAGLGYPTLTR---------LLLKAGADIH-------AENEEPL 296 Query: 297 TPL 299 PL Sbjct: 297 CPL 299 Score = 38.2 bits (87), Expect = 0.014, Method: Composition-based stats. Identities = 23/99 (23%), Positives = 33/99 (33%), Gaps = 20/99 (20%) Query: 155 AQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLR-----------ACGRFFQKHQ 203 A + G++ LH+A +LL++ GAD+H + Sbjct: 253 ANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDSDSDSE 312 Query: 204 G-----TCFYFGELPLSLAACTKQWDVVTYLLENPHQPA 237 G + G PL L TK V LL N Q Sbjct: 313 GPEKDTRSSFRGHTPLDLTCSTK----VKTLLLNAAQNT 347 >6BY9-A nrPDB Length = 328 Score = 52.0 bits (123), Expect = 9e-07, Method: Composition-based stats. Identities = 33/165 (20%), Positives = 57/165 (34%), Gaps = 31/165 (18%) Query: 153 VNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGEL 212 ++ E S LH A E + +LV+ GA++ TC Sbjct: 91 IDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANI-------------DTCSEDQRT 137 Query: 213 PLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYD 272 PL AA + V YL++ A ++ D+ G+T LH + Sbjct: 138 PLMEAAENNHLEAVKYLIK---AGALVDPKDAEGSTCLHLAA---------KKGHYEVVQ 185 Query: 273 GLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQR 317 LL G + G TP+ A + +++ + +L + Sbjct: 186 YLLSNG------QMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSK 224 Score = 49.7 bits (117), Expect = 4e-06, Method: Composition-based stats. Identities = 41/192 (21%), Positives = 67/192 (34%), Gaps = 51/192 (26%) Query: 115 STGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEK 174 + G TCL A + G + LL +G + G + + A E Sbjct: 166 AEGSTCLHLAA---KKGHYEVVQYLLS----NGQM------DVNCQDDGGWTPMIWATEY 212 Query: 175 RSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPH 234 + + VKLL+ G+D+++R + L AA + D+ LL Sbjct: 213 KHVDLVKLLLSKGSDINIRDNEE-------------NICLHWAAFSGCVDIAEILL---A 256 Query: 235 QPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYD---GLLQMGARLCPTVQLEEIS 291 L A + G++ LH EN YD L + + + Sbjct: 257 AKCDLHAVNIHGDSPLHIAA------RENR------YDCVVLFLSRDSDV-------TLK 297 Query: 292 NHQGLTPLKLAA 303 N +G TPL+ A+ Sbjct: 298 NKEGETPLQCAS 309 >1BLX-B nrPDB Length = 166 Score = 51.7 bits (122), Expect = 1e-06, Method: Composition-based stats. Identities = 42/176 (23%), Positives = 61/176 (34%), Gaps = 39/176 (22%) Query: 78 DRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIM 137 DRL +RG +E+ LL D+ GKT L + Sbjct: 10 DRLSGAAARGDVQEVRRLLH----RELVHPDALNR---FGKTALQVMMFG-------SPA 55 Query: 138 PLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGR 197 L++ K +P + G S +H A L +K+LVE+GADV+ Sbjct: 56 VALELLKQGASP--------NVQDASGTSPVHDAARTGFLDTLKVLVEHGADVNA----- 102 Query: 198 FFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHAL 253 G LP+ LA VV++L + L D+ G T L Sbjct: 103 --------LDSTGSLPIHLAIREGHSSVVSFL----APESDLHHRDASGLTPLELA 146 Score = 45.5 bits (106), Expect = 8e-05, Method: Composition-based stats. Identities = 39/173 (22%), Positives = 65/173 (37%), Gaps = 37/173 (21%) Query: 150 KLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYF 209 + LV+ + F G +AL + + S L++ GA +++ Sbjct: 30 RELVHPDALNRF--GKTALQV-MMFGSPAVALELLKQGASPNVQDAS------------- 73 Query: 210 GELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIH 269 G P+ AA T D + L+E+ A + A DS G+ +H + +S + Sbjct: 74 GTSPVHDAARTGFLDTLKVLVEHG---ADVNALDSTGSLPIHLAIREGHSSVVS------ 124 Query: 270 MYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQREFSGP 322 L + L + GLTPL+LA + G + ILQ P Sbjct: 125 ----FLAPESDLHH-------RDASGLTPLELARQRG-AQNLMDILQGHMMIP 165 >1WG0-A nrPDB Length = 243 Score = 50.1 bits (118), Expect = 4e-06, Method: Composition-based stats. Identities = 30/130 (23%), Positives = 50/130 (38%), Gaps = 17/130 (13%) Query: 153 VNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGEL 212 + QG + LH+A+ K+ + + L+ENGA V ++ F ++ Sbjct: 96 LKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASVRIK-------------DKFNQI 142 Query: 213 PLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVL-HALVM-IADNSPENSALVIHM 270 PL AA ++ L +++ D G T L HAL D + Sbjct: 143 PLHRAASVGSLKLIELLC--GLGKSAVNWQDKQGWTPLFHALAEGHGDAAVLLVEKYGAE 200 Query: 271 YDGLLQMGAR 280 YD + GA+ Sbjct: 201 YDLVDNKGAK 210 Score = 42.8 bits (99), Expect = 6e-04, Method: Composition-based stats. Identities = 35/165 (21%), Positives = 58/165 (35%), Gaps = 29/165 (17%) Query: 161 FYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACT 220 G LH ++ ++ + L+ +V+L + G P +A Sbjct: 33 DQDGRIPLHWSVSFQAHEITSFLLSKMENVNL-------DDYPDDS---GWTPFHIACSV 82 Query: 221 KQWDVVTYLLENPHQPASLEATDSLGNTVLHALV-----MIADNSPENSALV--IHMYDG 273 +VV L + P +P L + G T LH V ++ EN A V ++ Sbjct: 83 GNLEVVKSLYDRPLKP-DLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASVRIKDKFNQ 141 Query: 274 L-LQMGARLCPTVQLEEI----------SNHQGLTPLKLAAKEGK 307 + L A + +E + + QG TPL A EG Sbjct: 142 IPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGH 186 >3UI2-A nrPDB Length = 244 Score = 48.6 bits (114), Expect = 1e-05, Method: Composition-based stats. Identities = 30/122 (24%), Positives = 45/122 (36%), Gaps = 15/122 (12%) Query: 143 DKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKH 202 + +LL + G +AL S +CV+LL E GAD+ Sbjct: 56 ADEQALSQLLEDRDVDAVDENGRTALLFVAGLGSDKCVRLLAEAGADLD----------- 104 Query: 203 QGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPE 262 G L +AA + +VV L+E A +E D G T L I +P+ Sbjct: 105 -HRDMRGGLTALHMAAGYVRPEVVEALVE---LGADIEVEDERGLTALELAREILKTTPK 160 Query: 263 NS 264 + Sbjct: 161 GN 162 >3DEO-A nrPDB Length = 183 Score = 48.6 bits (114), Expect = 1e-05, Method: Composition-based stats. Identities = 30/122 (24%), Positives = 45/122 (36%), Gaps = 15/122 (12%) Query: 143 DKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKH 202 + +LL + G +AL S +CV+LL E GAD+ Sbjct: 55 ADEQALSQLLEDRDVDAVDENGRTALLFVAGLGSDKCVRLLAEAGADLD----------- 103 Query: 203 QGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPE 262 G L +AA + +VV L+E A +E D G T L I +P+ Sbjct: 104 -HRDMRGGLTALHMAAGYVRPEVVEALVE---LGADIEVEDERGLTALELAREILKTTPK 159 Query: 263 NS 264 + Sbjct: 160 GN 161 >4O1O-A nrPDB Length = 717 Score = 46.7 bits (109), Expect = 3e-05, Method: Composition-based stats. Identities = 47/199 (23%), Positives = 71/199 (35%), Gaps = 40/199 (20%) Query: 81 FSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGST------GKTCLMKAVLNLQDGVNA 134 F+ L +L N + T+ G T LM A GV Sbjct: 109 FTAFMEAAVYGRVEALRFLYENGADVNMHRKTKQDQERIRKGGATALMDAAEKGHVGV-- 166 Query: 135 CIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEK----RSLQCVKLLVENGADV 190 + LL K A+ G +AL A+ ++ +LL+++GADV Sbjct: 167 -VTILLHAMK----------AEVDARDNMGRNALVYALLNPDDGKAKAITRLLLDHGADV 215 Query: 191 HLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVL 250 ++R G + PL LA K D+V LLE + + TD G T L Sbjct: 216 NVRGEGS-------------KTPLILAVERKNLDLVQMLLE--QEQIEVNDTDREGKTAL 260 Query: 251 HALVMIADNSPENSALVIH 269 L+ + E + L+ H Sbjct: 261 --LLAVELRLEEIAKLLCH 277 Score = 46.7 bits (109), Expect = 4e-05, Method: Composition-based stats. Identities = 42/187 (22%), Positives = 67/187 (35%), Gaps = 32/187 (17%) Query: 141 QIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQ 200 I++ + +A +E + G S LH A++ S V LL+++GAD LR Sbjct: 20 DIEQVRQLLERGADANFQEEEW-GWSPLHSAVQMDSEDLVALLLKHGADPCLRKRN---- 74 Query: 201 KHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNS 260 G P +A T ++ LL N + D G T + Sbjct: 75 ---------GATPFIIAGITGNVRLLQLLLPNVE---DVNECDVNGFTAFMEAAVYGR-- 120 Query: 261 PENSALVIHMYDGLLQMGARLC---PTVQLEEISNHQGLTPLKLAAKEGKIE---IFRHI 314 + L + GA + T Q +E G T L AA++G + I H Sbjct: 121 -------VEALRFLYENGADVNMHRKTKQDQERIRKGGATALMDAAEKGHVGVVTILLHA 173 Query: 315 LQREFSG 321 ++ E Sbjct: 174 MKAEVDA 180 Score = 40.9 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 32/136 (23%), Positives = 49/136 (36%), Gaps = 31/136 (22%) Query: 80 LFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGV-NACIMP 138 L +G G++ L K D+ + G+ L+ A+LN DG A Sbjct: 155 LMDAAEKGHV----GVVTILLHAMKAEVDA---RDNMGRNALVYALLNPDDGKAKAITRL 207 Query: 139 LLQIDKD-----SGNPKLLVNA------------------QCTDEFYQGHSALHIAIEKR 175 LL D G+ L+ A + D +G +AL +A+E R Sbjct: 208 LLDHGADVNVRGEGSKTPLILAVERKNLDLVQMLLEQEQIEVNDTDREGKTALLLAVELR 267 Query: 176 SLQCVKLLVENGADVH 191 + KLL GA + Sbjct: 268 LEEIAKLLCHRGASTN 283 Score = 40.1 bits (92), Expect = 0.003, Method: Composition-based stats. Identities = 32/144 (22%), Positives = 56/144 (38%), Gaps = 31/144 (21%) Query: 171 AIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLL 230 A+++ ++ V+ L+E GAD + FQ+ + +G PL A D+V LL Sbjct: 15 AVQEADIEQVRQLLERGADAN-------FQEEE-----WGWSPLHSAVQMDSEDLVALLL 62 Query: 231 ENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEI 290 ++ P L + G T + + + + LL P V+ Sbjct: 63 KHGADPC-LRKRN--GATPFIIAGITGN---------VRLLQLLL-------PNVEDVNE 103 Query: 291 SNHQGLTPLKLAAKEGKIEIFRHI 314 + G T AA G++E R + Sbjct: 104 CDVNGFTAFMEAAVYGRVEALRFL 127 >1G3N-B nrPDB Length = 168 Score = 45.5 bits (106), Expect = 8e-05, Method: Composition-based stats. Identities = 41/180 (22%), Positives = 63/180 (35%), Gaps = 38/180 (21%) Query: 80 LFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIMPL 139 L S +RG E+LT LL+ + G+T L L L Sbjct: 9 LASAAARGDLEQLTSLLQNNVNVNAQNG--------FGRTALQVMKL---GNPEIARRLL 57 Query: 140 LQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFF 199 L NP L + G + +H A L ++ L+E ADV++ Sbjct: 58 L----RGANPDL--------KDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNE--- 102 Query: 200 QKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADN 259 G LPL LAA VV +L++ H +++ + G+T + N Sbjct: 103 ----------GNLPLHLAAKEGHLRVVEFLVK--HTASNVGHRNHKGDTACDLARLYGRN 150 Score = 32.8 bits (73), Expect = 0.51, Method: Composition-based stats. Identities = 23/108 (21%), Positives = 41/108 (37%), Gaps = 20/108 (18%) Query: 209 FGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVI 268 FG L + ++ LL + A+ + D G V+H + Sbjct: 37 FGRTALQVMK-LGNPEIARRLL---LRGANPDLKDRTGFAVIHDAARAGFLDTLQT---- 88 Query: 269 HMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQ 316 LL+ A + I +++G PL LAAKEG + + +++ Sbjct: 89 -----LLEFQADVN-------IEDNEGNLPLHLAAKEGHLRVVEFLVK 124 >5DND-A nrPDB Length = 588 Score = 45.5 bits (106), Expect = 9e-05, Method: Composition-based stats. Identities = 43/203 (21%), Positives = 65/203 (32%), Gaps = 39/203 (19%) Query: 130 DGVNACIMPLLQID-KDSGNPKLL-----VNAQCTDEFYQGHSALHIAIEKRSLQCVKLL 183 D V +MP L + +G + L + + + G + LH+A V +L Sbjct: 415 DSVQDAVMPSLALALAHAGELEALQALMELGSDLRLKDSNGQTLLHVAARNGRDGVVTML 474 Query: 184 VENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATD 243 + G DV+ R G PL LA + + + L + A L D Sbjct: 475 LHRGMDVNARDRD-------------GLSPLLLAVQGRHRECIRLLRK---AGACLSPQD 518 Query: 244 SL-GNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLA 302 T L L AD + Q GA L + G + L +A Sbjct: 519 LKDAGTELCRLASRADMEGLQAWG---------QAGADLQQ-------PGYDGRSALCVA 562 Query: 303 AKEGKIEIFRHILQREFSGPYQP 325 G E+ + GP P Sbjct: 563 EAAGNQEVLALLRNLALVGPEVP 585 Score = 39.7 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 29/122 (23%), Positives = 44/122 (36%), Gaps = 20/122 (16%) Query: 214 LSLA-ACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYD 272 L+LA A + + + L+E + L DS G T+LH + + Sbjct: 425 LALALAHAGELEALQALME---LGSDLRLKDSNGQTLLHVAARNGRDG---------VVT 472 Query: 273 GLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQREFSGPYQPLSRKFTE 332 LL G + + GL+PL LA + E R + + Q L TE Sbjct: 473 MLLHRGMDV-------NARDRDGLSPLLLAVQGRHRECIRLLRKAGACLSPQDLKDAGTE 525 Query: 333 WC 334 C Sbjct: 526 LC 527 Score = 35.9 bits (81), Expect = 0.062, Method: Composition-based stats. Identities = 33/107 (30%), Positives = 48/107 (44%), Gaps = 22/107 (20%) Query: 87 GVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDS 146 G E L L+E + L D S G+T L A N +DGV + LL D Sbjct: 433 GELEALQALME--LGSDLRLKD------SNGQTLLHVAARNGRDGV---VTMLLHRGMD- 480 Query: 147 GNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLR 193 VNA+ D G S L +A++ R +C++LL + GA + + Sbjct: 481 ------VNARDRD----GLSPLLLAVQGRHRECIRLLRKAGACLSPQ 517 >3ZKJ-A nrPDB Length = 261 Score = 45.5 bits (106), Expect = 9e-05, Method: Composition-based stats. Identities = 34/151 (22%), Positives = 56/151 (37%), Gaps = 33/151 (21%) Query: 166 SALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDV 225 S LH A L CVK+L+++GA V+ PL A + WD Sbjct: 38 SPLHEACLGGHLSCVKILLKHGAQVNGVTADW-------------HTPLFNACVSGSWDC 84 Query: 226 VTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTV 285 V LL++ AS++ L + +H + + L+ G + + Sbjct: 85 VNLLLQHG---ASVQPESDLA-SPIHEAARRGH---------VECVNSLIAYGGNIDHKI 131 Query: 286 QLEEISNHQGLTPLKLAAKEGKIEIFRHILQ 316 H G TPL LA + + + +L+ Sbjct: 132 S------HLG-TPLYLACENQQRACVKKLLE 155 Score = 42.0 bits (97), Expect = 9e-04, Method: Composition-based stats. Identities = 46/201 (22%), Positives = 65/201 (32%), Gaps = 41/201 (20%) Query: 155 AQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVH-----LRACGRFFQKHQGTCF-- 207 AQ H+ L A S CV LL+++GA V ++ C Sbjct: 60 AQVNGVTADWHTPLFNACVSGSWDCVNLLLQHGASVQPESDLASPIHEAARRGHVECVNS 119 Query: 208 ---YFGE---------LPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVM 255 Y G PL LA +Q V LLE+ + DS LHA+ Sbjct: 120 LIAYGGNIDHKISHLGTPLYLACENQQRACVKKLLESGADVNQGKGQDS----PLHAVAR 175 Query: 256 IADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHIL 315 A + L+ GA N +G P++L E + + L Sbjct: 176 TASE---------ELACLLMDFGADTQ-------AKNAEGKRPVELVPPESPLA--QLFL 217 Query: 316 QREFSGPYQPLSRKFTEWCYG 336 +RE L R C+G Sbjct: 218 EREGPPSLMQLCRLRIRKCFG 238 >3EU9-A nrPDB Length = 240 Score = 44.7 bits (104), Expect = 2e-04, Method: Composition-based stats. Identities = 35/154 (22%), Positives = 55/154 (35%), Gaps = 34/154 (22%) Query: 163 QGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAAC-TK 221 +G S +H+A + V L+ G DV + G PL AA T Sbjct: 108 EGCSCIHLAAQFGHTSIVAYLIAKGQDVDM-------------MDQNGMTPLMWAAYRTH 154 Query: 222 QWDVVTYLLENPHQPASLEATDSL-GNTVLHALVMIADNSPENSALVIHMYDGLLQMGAR 280 D LL S+ D NT LH V+ + + + LL+ GA Sbjct: 155 SVDPTRLLL---TFNVSVNLGDKYHKNTALHWAVLAGNTT---------VISLLLEAGAN 202 Query: 281 LCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHI 314 + + N +G + L LA + + + H+ Sbjct: 203 V-------DAQNIKGESALDLAKQRKNVWMINHL 229 Score = 42.0 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 29/156 (18%), Positives = 48/156 (30%), Gaps = 33/156 (21%) Query: 150 KLLVNA--QCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCF 207 + LV A + + LH A + VK + GA V Q Sbjct: 26 RELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIV-----------DQLGGD 74 Query: 208 YFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALV 267 PL A +V L++ P+ + D G + +H Sbjct: 75 -LNSTPLHWATRQGHLSMVVQLMKYGADPSLI---DGEGCSCIHLAAQFGH--------- 121 Query: 268 IHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAA 303 + L+ G + ++ + G+TPL AA Sbjct: 122 TSIVAYLIAKGQDV-------DMMDQNGMTPLMWAA 150 Score = 34.7 bits (78), Expect = 0.16, Method: Composition-based stats. Identities = 26/125 (20%), Positives = 45/125 (36%), Gaps = 28/125 (22%) Query: 93 TGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPK-- 150 G L + KY D + +G G +C+ A Q G + + L+ +D Sbjct: 86 QGHLSMVVQLMKYGADPSLIDGE-GCSCIHLAA---QFGHTSIVAYLIAKGQDVDMMDQN 141 Query: 151 ---LLVNAQCTD-------------------EFYQGHSALHIAIEKRSLQCVKLLVENGA 188 L+ A + Y ++ALH A+ + + LL+E GA Sbjct: 142 GMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGA 201 Query: 189 DVHLR 193 +V + Sbjct: 202 NVDAQ 206 >3T9K-A nrPDB Length = 390 Score = 42.8 bits (99), Expect = 6e-04, Method: Composition-based stats. Identities = 38/167 (22%), Positives = 54/167 (32%), Gaps = 25/167 (14%) Query: 71 EPDRFDRDRLFSVVSRGVP--EELTGLLE--YLRWNSKYLTDSAYTEGSTGKTCLMKAVL 126 P R R + S+ P E+L L L S + + + A + Sbjct: 171 PPKPSIRPRPGDLRSKPEPPSEDLGSLHPGALLFRASGHPP----SLPTMADALAHGADV 226 Query: 127 NLQDGVNACIMPLLQIDKDSGNPK---LLVN-AQCTDEFYQGHSALHIAIEKRSLQCVKL 182 N +G PL+Q + LL N A G LH A L Sbjct: 227 NWVNGGQDNATPLIQATAANSLLACEFLLQNGANVNQADSAGRGPLHHATILGHTGLACL 286 Query: 183 LVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYL 229 ++ GAD+ R G PL++A T D+VT L Sbjct: 287 FLKRGADLGAR-------------DSEGRDPLTIAMETANADIVTLL 320 Score = 34.7 bits (78), Expect = 0.15, Method: Composition-based stats. Identities = 22/93 (23%), Positives = 33/93 (35%), Gaps = 16/93 (17%) Query: 166 SALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDV 225 + L A SL + L++NGA+V+ G PL A + Sbjct: 237 TPLIQATAANSLLACEFLLQNGANVNQADSA-------------GRGPLHHATILGHTGL 283 Query: 226 VTYLLENPHQPASLEATDSLGNTVLHALVMIAD 258 L+ + A L A DS G L + A+ Sbjct: 284 ACLFLK---RGADLGARDSEGRDPLTIAMETAN 313 >6EMK-G nrPDB Length = 426 Score = 42.0 bits (97), Expect = 8e-04, Method: Composition-based stats. Identities = 32/162 (19%), Positives = 50/162 (30%), Gaps = 37/162 (22%) Query: 96 LEYLRWNSKYLTD----------SAYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKD 145 L Y ++ +YL + G TC+ A++ G + LLQ Sbjct: 44 LHYASYHGRYLICVYLIQLGHDKHELIKTFKGNTCVHLALMK---GHEQTLHLLLQ---- 96 Query: 146 SGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGT 205 +N G + +HIA QC+ LL+ GAD+ + Sbjct: 97 --QFPRFIN----HRGENGRAPIHIACMNDYYQCLSLLIGVGADLWVMDTN--------- 141 Query: 206 CFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGN 247 G+ PL + + LL D GN Sbjct: 142 ----GDTPLHVCLEYGSISCMKMLLNEGEVSLDDNVRD-KGN 178 Score = 37.8 bits (86), Expect = 0.018, Method: Composition-based stats. Identities = 35/179 (19%), Positives = 64/179 (35%), Gaps = 33/179 (18%) Query: 79 RLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIMP 138 RL + G + L LR N LT+ + G + L A G + Sbjct: 8 RLREAIIEGNLLIVKRL---LRRNPDLLTN---IDSENGWSSLHYAS---YHGRYLICVY 58 Query: 139 LLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRF 198 L+Q+ D + ++G++ +H+A+ K Q + LL++ F Sbjct: 59 LIQLGHDKHEL---------IKTFKGNTCVHLALMKGHEQTLHLLLQQ-----------F 98 Query: 199 FQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIA 257 + G P+ +A + ++ L+ A L D+ G+T LH + Sbjct: 99 PRFINHRG-ENGRAPIHIACMNDYYQCLSLLI---GVGADLWVMDTNGDTPLHVCLEYG 153 >3EHQ-A nrPDB Length = 222 Score = 42.0 bits (97), Expect = 9e-04, Method: Composition-based stats. Identities = 29/161 (18%), Positives = 53/161 (32%), Gaps = 34/161 (21%) Query: 167 ALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVV 226 LH A ++ +L ++ ++N V+ G L A D+V Sbjct: 76 PLHEAAKRGNLSWLRECLDNRVGVN-------------GLDKAGSTALYWACHGGHKDIV 122 Query: 227 TYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQ 286 L P+ L + LG+T LHA + LL GAR Sbjct: 123 EMLFTQPN--IELNQQNKLGDTALHAAAWKG---------YADIVQLLLAKGAR------ 165 Query: 287 LEEISNHQGLTPLKLAAKEGKIEIFRHILQREFSGPYQPLS 327 ++ N + +A + + +++ + + LS Sbjct: 166 -TDLRNIEKKLAFDMATNAACASLLK---KKQGTDAVRTLS 202 Score = 38.2 bits (87), Expect = 0.013, Method: Composition-based stats. Identities = 26/103 (25%), Positives = 33/103 (32%), Gaps = 27/103 (26%) Query: 117 GKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRS 176 G T L A G + L N + + G +ALH A K Sbjct: 106 GSTALYWAC---HGGHKDIVEMLFTQP----------NIELNQQNKLGDTALHAAAWKGY 152 Query: 177 LQCVKLLVENGADVHLR--------------ACGRFFQKHQGT 205 V+LL+ GA LR AC +K QGT Sbjct: 153 ADIVQLLLAKGARTDLRNIEKKLAFDMATNAACASLLKKKQGT 195 >4BSZ-B nrPDB Length = 202 Score = 42.0 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 33/163 (20%), Positives = 55/163 (33%), Gaps = 19/163 (11%) Query: 69 QQEPDRFDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNL 128 + D+ D+D + G + L + L T E + T L A N Sbjct: 7 SEPLDQEDQDTIILDARAGDLDSLKDIFTTLVSPELLSTC---KESESDSTALHMAAANG 63 Query: 129 QDGVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGA 188 I+ + + + K VN + G++ALH A L VKLL + Sbjct: 64 HIETVRYILETVSRANSAEDLKAFVN----EVNKTGNTALHWASLNGKLDVVKLLCDE-- 117 Query: 189 DVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLE 231 ++ FG + A + + +V TY L+ Sbjct: 118 ----------YEADPFIRNKFGHDAIFEAENSGKEEVETYFLK 150 Score = 35.1 bits (79), Expect = 0.13, Method: Composition-based stats. Identities = 23/123 (18%), Positives = 42/123 (34%), Gaps = 12/123 (9%) Query: 141 QIDKDSGNPKLLVNAQCTD---EFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGR 197 +D LV+ + E +ALH+A ++ V+ ++E + + + Sbjct: 26 DLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETVSRANSAEDLK 85 Query: 198 FFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIA 257 F G L A+ + DVV L + + N H + A Sbjct: 86 AFVNEVNKT---GNTALHWASLNGKLDVVKLLCDEYEADPFIR------NKFGHDAIFEA 136 Query: 258 DNS 260 +NS Sbjct: 137 ENS 139 Score = 33.6 bits (75), Expect = 0.38, Method: Composition-based stats. Identities = 22/113 (19%), Positives = 36/113 (31%), Gaps = 22/113 (19%) Query: 212 LPLSLAACTKQWDVVTYLLENPHQ-------PASLEATDSLGNTVLHALVMIADNSPENS 264 L +AA + V Y+LE + A + + GNT LH + Sbjct: 54 TALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGK------ 107 Query: 265 ALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQR 317 D + + I N G + A GK E+ + L++ Sbjct: 108 ------LDVVKLLCDEYEADP---FIRNKFGHDAIFEAENSGKEEVETYFLKK 151 >5U0K-A nrPDB Length = 141 Score = 40.1 bits (92), Expect = 0.004, Method: Composition-based stats. Identities = 20/95 (21%), Positives = 34/95 (35%), Gaps = 14/95 (14%) Query: 137 MPLLQIDKDSGNPKLLVNA--QCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRA 194 + D + + + Y +ALH+A + ++ VK L+E V+ A Sbjct: 29 LLFAAYSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEA-CKVNPFA 87 Query: 195 CGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYL 229 R +G +PL A +VV L Sbjct: 88 KDR-----------WGNIPLDDAVQFNHLEVVKLL 111 Score = 32.8 bits (73), Expect = 0.61, Method: Composition-based stats. Identities = 19/79 (24%), Positives = 24/79 (30%), Gaps = 3/79 (3%) Query: 177 LQCVKLLVEN-GADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQ 235 V LL DV Y L +AA +VV +L+E Sbjct: 24 KTVVNLLFAAYSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIE--AC 81 Query: 236 PASLEATDSLGNTVLHALV 254 + A D GN L V Sbjct: 82 KVNPFAKDRWGNIPLDDAV 100 >2KXP-C nrPDB Length = 118 Score = 39.3 bits (90), Expect = 0.005, Method: Composition-based stats. Identities = 21/105 (20%), Positives = 32/105 (30%), Gaps = 18/105 (17%) Query: 155 AQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPL 214 G LH A + L+ ++ L+ GAD++ PL Sbjct: 26 EDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPDKHHI-------------TPL 72 Query: 215 SLAACTKQWDVVTYLLENPHQ-----PASLEATDSLGNTVLHALV 254 A V LL P L A ++ N + AL+ Sbjct: 73 LSAVYEGHVSCVKLLLSKGADKTVKGPDGLTALEATDNQAIKALL 117 Score = 30.1 bits (66), Expect = 3.6, Method: Composition-based stats. Identities = 13/39 (33%), Positives = 18/39 (46%) Query: 151 LLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGAD 189 LL A + L A+ + + CVKLL+ GAD Sbjct: 55 LLKGADINAPDKHHITPLLSAVYEGHVSCVKLLLSKGAD 93 >5D68-A nrPDB Length = 486 Score = 39.3 bits (90), Expect = 0.006, Method: Composition-based stats. Identities = 18/86 (20%), Positives = 30/86 (34%), Gaps = 14/86 (16%) Query: 167 ALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVV 226 +H A ++ ++L+E G G+ PL AA ++V Sbjct: 74 PIHYACWYGKVEATRILLEKGKCNPNLLNGQL------------SSPLHFAAGGGHAEIV 121 Query: 227 TYLLENPHQPASLEATDSLGNTVLHA 252 LL +P TD G + L+ Sbjct: 122 QILLNHP--ETDRHITDQQGRSPLNI 145 >6BWI-A nrPDB Length = 977 Score = 39.3 bits (90), Expect = 0.007, Method: Composition-based stats. Identities = 38/158 (24%), Positives = 63/158 (39%), Gaps = 6/158 (3%) Query: 519 FQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVSLSREARSPKAPEDNNSTVTEQ 578 + G V++ K+ ++D+ FL V+L + VA L R S Sbjct: 714 NKQLGPKIVIVSKM-MKDVFFFLFFLGVWLVAYGVATEGLLRPRDSDFPSILRRVFYRPY 772 Query: 579 PTVG----QEEEPAPYRSILDASLEL-FKFTIGMGELAFQEQLRFRGVVLLLLLAYVLLT 633 + QE+ + S E F + +V+LLL+ ++L+ Sbjct: 773 LQIFGQIPQEDMDVALMEHSNCSSEPGFWAHPPGAQAGTCVSQYANWLVVLLLVIFLLVA 832 Query: 634 YVLLLNMLIALMSETVNHVADNSWSIWKLQKAISVLEM 671 +LL+N+LIA+ S T V NS WK Q+ + E Sbjct: 833 NILLVNLLIAMFSYTFGKVQGNSDLYWKAQRYRLIREF 870 >5Z1W-A nrPDB Length = 566 Score = 37.4 bits (85), Expect = 0.022, Method: Composition-based stats. Identities = 41/270 (15%), Positives = 93/270 (34%), Gaps = 47/270 (17%) Query: 386 WDRLVSRFFFNFACYLVYMFIFTVVAYHQPSLDQPAIPSSKATFGESMLLLGHILILLGG 445 WD + F ++ Y + ++ H L SS + +++L I+ + G Sbjct: 285 WDFFIVGCEVVFCVFIFYYVVEEILEIHLHRLR---YLSSVWNILDLVVILLSIVAV-GF 340 Query: 446 IYLLLGQLWYFWRRRLFIWISFMDSYFEILFLLQALLTVLSQVLRFMETEWYLPLLVLSL 505 ++ + L ++ D FE L Q ++ V +L Sbjct: 341 HIFRTLEVNRLMGKLLQQPDTYAD--FEFLAFWQTQYNNMNAV---------------NL 383 Query: 506 VLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVSLSREARSP 565 W+ + Y + S + + +D+L F +++ + F +A L L Sbjct: 384 FFAWIKIFKYISFNKTMTQLSSTLARCA-KDILGFAIMFFIVFFAYAQ-LGYLLFGT--- 438 Query: 566 KAPEDNNSTVTEQPTVGQEEEPAPYRSILDASLELFKFTIGMGELAFQEQLRFRGVVLLL 625 + + + + F+ +G + + R + + Sbjct: 439 --------------------QVENFSTFVKCIFTQFRIILGDFDYNAIDNAN-RILGPVY 477 Query: 626 LLAYVLLTYVLLLNMLIALMSETVNHVADN 655 + YV + +LLNM +A++++T + V + Sbjct: 478 FVTYVFFVFFVLLNMFLAIINDTYSEVKEE 507 >5T4D-A nrPDB Length = 510 Score = 37.4 bits (85), Expect = 0.025, Method: Composition-based stats. Identities = 38/284 (13%), Positives = 95/284 (33%), Gaps = 49/284 (17%) Query: 395 FNFACYLVYMFIFTVVAYHQPSLDQPAIPS-SKATFGESMLLLGHILILLGGIYLLLGQL 453 N C + + F PS + T + L I+ Y ++ ++ Sbjct: 241 INLFCVVRLLVEFPATGGVIPSWQFQPLKLIRYVTTFDFFLAACEIIFCFFIFYYVVEEI 300 Query: 454 WYFWRRRLFIW---ISFMDSYFEILFLLQALLTV-----LSQVLRFMETEWYLP------ 499 +L + + +D +L ++ + + + +L+F+E + P Sbjct: 301 LEIRIHKLHYFRSFWNCLDVVIVVLSVVAIGINIYRTSNVEVLLQFLEDQNTFPNFEHLA 360 Query: 500 --------LLVLSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGF 551 + +++ W+ L + + S + + +DL F +++ + + Sbjct: 361 YWQIQFNNIAAVTVFFVWIKLFKFINFNRTMSQLSTTMSRCA-KDLFGFAIMFFIIFLAY 419 Query: 552 AVALVSLSREARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDASLELFKFTIGMGELA 611 A L L + + + + F+ +G A Sbjct: 420 AQ-LAYLVFGT-----------------------QVDDFSTFQECIFTQFRIILGDINFA 455 Query: 612 FQEQLRFRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNHVADN 655 E+ R + + +V + +LLNM +A++++T + V + Sbjct: 456 EIEEAN-RVLGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKSD 498 >6DU8-A nrPDB Length = 805 Score = 37.0 bits (84), Expect = 0.035, Method: Composition-based stats. Identities = 35/270 (12%), Positives = 84/270 (31%), Gaps = 47/270 (17%) Query: 386 WDRLVSRFFFNFACYLVYMFIFTVVAYHQPSLDQPAIPSSKATFGESMLLLGHILILLGG 445 WD + F ++ Y + + L I +L Sbjct: 348 WDFFIVGCEVIFCVFIFYYVV----------------EEILELHIHRLRYLSSIWNILDL 391 Query: 446 IYLLLGQLWYFWRRRLFIWISFMDSYFEILFLLQALLTVLSQVLRFMETEWYLPLLVLSL 505 + +LL + + + ++ + A L+ Y + ++L Sbjct: 392 VVILLSIVAVGFHIFRTLEVNRLMGKLLQQPNTYADFEFLA-----FWQTQYNNMNAVNL 446 Query: 506 VLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVSLSREARSP 565 W+ + Y + S + + +D+L F +++ + F +A L L Sbjct: 447 FFAWIKIFKYISFNKTMTQLSSTLARCA-KDILGFAVMFFIVFFAYAQ-LGYLLFGT--- 501 Query: 566 KAPEDNNSTVTEQPTVGQEEEPAPYRSILDASLELFKFTIGMGELAFQEQLRFRGVVLLL 625 + + + + F+ +G + + R + Sbjct: 502 --------------------QVENFSTFIKCIFTQFRIILGDFDYNAIDNAN-RILGPAY 540 Query: 626 LLAYVLLTYVLLLNMLIALMSETVNHVADN 655 + YV + +LLNM +A++++T + V + Sbjct: 541 FVTYVFFVFFVLLNMFLAIINDTYSEVKEE 570 >5MKE-A nrPDB Length = 968 Score = 36.6 bits (83), Expect = 0.044, Method: Composition-based stats. Identities = 38/284 (13%), Positives = 95/284 (33%), Gaps = 49/284 (17%) Query: 395 FNFACYLVYMFIFTVVAYHQPSLDQPAIPS-SKATFGESMLLLGHILILLGGIYLLLGQL 453 N C + + F PS + T + L I+ Y ++ ++ Sbjct: 433 INLFCVVRLLVEFPATGGVIPSWQFQPLKLIRYVTTFDFFLAACEIIFCFFIFYYVVEEI 492 Query: 454 WYFWRRRLFIW---ISFMDSYFEILFLLQALLTV-----LSQVLRFMETEWYLP------ 499 +L + + +D +L ++ + + + +L+F+E + P Sbjct: 493 LEIRIHKLHYFRSFWNCLDVVIVVLSVVAIGINIYRTSNVEVLLQFLEDQNTFPNFEHLA 552 Query: 500 --------LLVLSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGF 551 + +++ W+ L + + S + + +DL F +++ + + Sbjct: 553 YWQIQFNNIAAVTVFFVWIKLFKFINFNRTMSQLSTTMSRCA-KDLFGFAIMFFIIFLAY 611 Query: 552 AVALVSLSREARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDASLELFKFTIGMGELA 611 A L L + + + + F+ +G A Sbjct: 612 AQ-LAYLVFGT-----------------------QVDDFSTFQECIFTQFRIILGDINFA 647 Query: 612 FQEQLRFRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNHVADN 655 E+ R + + +V + +LLNM +A++++T + V + Sbjct: 648 EIEEAN-RVLGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKSD 690 >5UQE-A nrPDB Length = 520 Score = 35.9 bits (81), Expect = 0.061, Method: Composition-based stats. Identities = 14/78 (17%), Positives = 26/78 (33%), Gaps = 3/78 (3%) Query: 137 MPLLQIDKDSGNPKLLVNA--QCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRA 194 + D + + Y +ALH+A + ++ VK L+E V+ Sbjct: 421 LLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEA-CKVNPFP 479 Query: 195 CGRFFQKHQGTCFYFGEL 212 R+ +FG Sbjct: 480 KDRWNNTPMDEALHFGHH 497 Score = 30.1 bits (66), Expect = 3.3, Method: Composition-based stats. Identities = 14/60 (23%), Positives = 20/60 (33%), Gaps = 1/60 (1%) Query: 173 EKRSLQCVKLLVEN-GADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLE 231 ++R + LL DV Y L +AA +VV +LLE Sbjct: 412 DQRVKSVINLLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLE 471 >5U0J-A nrPDB Length = 140 Score = 35.9 bits (81), Expect = 0.061, Method: Composition-based stats. Identities = 14/78 (17%), Positives = 26/78 (33%), Gaps = 3/78 (3%) Query: 137 MPLLQIDKDSGNPKLLVNA--QCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRA 194 + D + + Y +ALH+A + ++ VK L+E V+ Sbjct: 28 LLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEA-CKVNPFP 86 Query: 195 CGRFFQKHQGTCFYFGEL 212 R+ +FG Sbjct: 87 KDRWNNTPMDEALHFGHH 104 Score = 29.3 bits (64), Expect = 6.7, Method: Composition-based stats. Identities = 12/50 (24%), Positives = 15/50 (30%) Query: 182 LLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLE 231 L DV Y L +AA +VV +LLE Sbjct: 29 LFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLE 78 >5WPT-A nrPDB Length = 592 Score = 34.7 bits (78), Expect = 0.15, Method: Composition-based stats. Identities = 49/273 (17%), Positives = 95/273 (34%), Gaps = 65/273 (23%) Query: 419 QPAIPSSKATFGE-SMLLLGHILILLGGIYLLLGQ--------------LWYFWRRR--- 460 Q S + G+ S LL ++++L L + + WRRR Sbjct: 282 QECKHPSVSRHGDNSFRLLFDVVVILTCSLSFLLCARSLLRGFLLQNEFVVFMWRRRGRE 341 Query: 461 LFIWI--SFMDSYFEILFLLQALLTVLSQVLR-------FMETEWYLPLLVLSLVLGWLN 511 + +W F++ ++ IL + +LT+ V++ + LL S +L W+ Sbjct: 342 ISLWERLEFVNGWY-ILLVTSDVLTISGTVMKIGIEAKNLASYDVCSILLGTSTLLVWVG 400 Query: 512 LLYYTRGFQHTGIYSVMIQ--KVILRDLLRFLLVYLVFLFGFAVALVSLSREARSPKAPE 569 ++ Y F Y+++I +V L ++RF V G+ + Sbjct: 401 VIRYLTFFHK---YNILIATLRVALPSVMRFCCCVAVIYLGYCFCGWIVLGPYHV----- 452 Query: 570 DNNSTVTEQPTVGQEEEPAPYRSILDASLELFKFTIGMGEL-------AFQEQLRFRGVV 622 +RS+ S LF G A Q + Sbjct: 453 -------------------KFRSLSMVSECLFSLINGDDMFVTFAAMQAQQGHSSLVWLF 493 Query: 623 LLLLL-AYVLLTYVLLLNMLIALMSETVNHVAD 654 L L +++ L ++L++ IAL++ + + Sbjct: 494 SQLYLYSFISLFIYMVLSLFIALITGAYDTIKH 526 >6E7Z-A nrPDB Length = 580 Score = 34.3 bits (77), Expect = 0.21, Method: Composition-based stats. Identities = 36/223 (16%), Positives = 79/223 (35%), Gaps = 38/223 (17%) Query: 443 LGGIYLLLGQLWYFWRRRLFI-WISFMDSYFEILFLLQALLTVLSQVLRFMETEWYLPLL 501 +G ++ G++ W R F+ + ++L + ++ + + + LL Sbjct: 331 VGFMWRQRGRVISLWERLEFVNGWYILLVTSDVLTISGTIMKIGIEAKNLASYDVCSILL 390 Query: 502 VLSLVLGWLNLLYYTRGFQHTGIYSVMIQ--KVILRDLLRFLLVYLVFLFGFAVALVSLS 559 S +L W+ ++ Y F + Y+++I +V L ++RF V G+ + Sbjct: 391 GTSTLLVWVGVIRYLTFFHN---YNILIATLRVALPSVMRFCCCVAVIYLGYCFCGWIVL 447 Query: 560 REARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDASLELFKFTIGMGEL-------AF 612 +RS+ S LF G A Sbjct: 448 GPYHV------------------------KFRSLSMVSECLFSLINGDDMFVTFAAMQAQ 483 Query: 613 QEQLRFRGVVLLLLL-AYVLLTYVLLLNMLIALMSETVNHVAD 654 Q + + L L +++ L ++L++ IAL++ + + Sbjct: 484 QGRSSLVWLFSQLYLYSFISLFIYMVLSLFIALITGAYDTIKH 526 >6D1W-A nrPDB Length = 740 Score = 33.9 bits (76), Expect = 0.24, Method: Composition-based stats. Identities = 38/284 (13%), Positives = 94/284 (33%), Gaps = 49/284 (17%) Query: 395 FNFACYLVYMFIFTVVAYHQPSLDQPAIPS-SKATFGESMLLLGHILILLGGIYLLLGQL 453 N C + + F PS + T + L I+ Y ++ ++ Sbjct: 381 INLFCVVRLLVEFPATGGVIPSWQFQPLKLIRYVTTFDFFLAACEIIFCFFIFYYVVEEI 440 Query: 454 WYFWRRRLFIW---ISFMDSYFEILFLLQALLTV-----LSQVLRFMETEWYLP------ 499 +L + + +D +L ++ + + + +L+F+E + P Sbjct: 441 LEIRIHKLHYFRSFWNCLDVVIVVLSVVAIGINIYRTSNVEVLLQFLEDQNTFPNFEHLA 500 Query: 500 --------LLVLSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGF 551 + +++ W+ L + + S + + +DL F ++ + + Sbjct: 501 YWQIQFNNIAAVTVFFVWIKLFKFINFNRTMSQLSTTMSRCA-KDLFGFAIMPFIIFLAY 559 Query: 552 AVALVSLSREARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDASLELFKFTIGMGELA 611 A L L + + + + F+ +G A Sbjct: 560 AQ-LAYLVFGT-----------------------QVDDFSTFQECIFTQFRIILGDINFA 595 Query: 612 FQEQLRFRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNHVADN 655 E+ R + + +V + +LLNM +A++++T + V + Sbjct: 596 EIEEAN-RVLGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKSD 638 >6AYG-A nrPDB Length = 558 Score = 33.9 bits (76), Expect = 0.24, Method: Composition-based stats. Identities = 33/196 (16%), Positives = 69/196 (35%), Gaps = 30/196 (15%) Query: 464 WISFMDSYFEILFLLQALLTVLSQVLRFMETEWYLPLLVLSLVLGWLNLLYYTRGFQHTG 523 M +IL ++ ++L + Q + LL S +L WL ++ Y F Sbjct: 345 GWYIMIIISDILTIIGSILKMEIQAKSLTSYDVCSILLGTSTMLVWLGVIRYLGFFAKYN 404 Query: 524 IYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVSLSREARSPKAPEDNNSTVTEQPTVGQ 583 + + +Q L +++RF + G+ + Sbjct: 405 LLILTLQAA-LPNVIRFCCCAAMIYLGYCFCGWIVLGPYHD------------------- 444 Query: 584 EEEPAPYRSILDASLELFKFTIGMGELA----FQEQLRFRGVVL-LLLLAYVLLTYVLLL 638 +RS+ S LF G A Q++ + + L +++ L ++L Sbjct: 445 -----KFRSLNMVSECLFSLINGDDMFATFAKMQQKSYLVWLFSRIYLYSFISLFIYMIL 499 Query: 639 NMLIALMSETVNHVAD 654 ++ IAL+++T + Sbjct: 500 SLFIALITDTYETIKQ 515 >3LJN-A nrPDB Length = 364 Score = 33.6 bits (75), Expect = 0.35, Method: Composition-based stats. Identities = 35/170 (20%), Positives = 55/170 (32%), Gaps = 47/170 (27%) Query: 164 GHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQW 223 G +ALH+A + + K L G +VH + G+ P+ LA + Sbjct: 53 GCTALHLACKFGCVDTAKYLASVG-EVHS--------------LWHGQKPIHLAVMANKT 97 Query: 224 DVVTYLLENPHQPAS-----LEATDSL-------------GNTVLHALVMIADNSPENSA 265 D+V L+E + L D G T LH V + Sbjct: 98 DLVVALVEGAKERGQMPESLLNECDEREVNEIGSHVKHCKGQTALHWCVGLGPE------ 151 Query: 266 LVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHIL 315 + M L+Q+GA + TPL A + E ++ Sbjct: 152 -YLEMIKILVQLGAS-------PTAKDKADETPLMRAMEFRNREALDLMM 193 >3LVQ-E nrPDB Length = 497 Score = 33.2 bits (74), Expect = 0.49, Method: Composition-based stats. Identities = 26/123 (21%), Positives = 43/123 (34%), Gaps = 22/123 (17%) Query: 66 APSQQEPDRFDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAV 125 P Q P+ V ++ L++++ N +L + + G T L A Sbjct: 164 GPDAQAPEELVLHLAVKVANQASLP----LVDFIIQNGGHLD----AKAADGNTALHYAA 215 Query: 126 LNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVE 185 L C+ LL+ A G +AL IA +K +C +LL + Sbjct: 216 LY---NQPDCLKLLLKG-----------RALVGTVNEAGETALDIARKKHHKECEELLEQ 261 Query: 186 NGA 188 A Sbjct: 262 AQA 264 >2B0O-E nrPDB Length = 301 Score = 33.2 bits (74), Expect = 0.49, Method: Composition-based stats. Identities = 26/123 (21%), Positives = 43/123 (34%), Gaps = 22/123 (17%) Query: 66 APSQQEPDRFDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAV 125 P Q P+ V ++ L++++ N +L + + G T L A Sbjct: 183 GPDAQAPEELVLHLAVKVANQASLP----LVDFIIQNGGHLD----AKAADGNTALHYAA 234 Query: 126 LNLQDGVNACIMPLLQIDKDSGNPKLLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVE 185 L C+ LL+ A G +AL IA +K +C +LL + Sbjct: 235 LY---NQPDCLKLLLKG-----------RALVGTVNEAGETALDIARKKHHKECEELLEQ 280 Query: 186 NGA 188 A Sbjct: 281 AQA 283 >1D9S-A nrPDB Length = 136 Score = 32.8 bits (73), Expect = 0.57, Method: Composition-based stats. Identities = 29/147 (19%), Positives = 53/147 (36%), Gaps = 32/147 (21%) Query: 168 LHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVT 227 L A + ++ V+ L+E GAD + FG P+ + V Sbjct: 16 LATAAARGQVETVRQLLEAGADPNALNR-------------FGRRPIQVMM-MGSAQVAE 61 Query: 228 YLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQL 287 LL + +P N A + + + + L + GARL Sbjct: 62 LLLLHGAEP----------NCADPATLTRPVHDAAREGFLDTLV-VLHRAGARL------ 104 Query: 288 EEISNHQGLTPLKLAAKEGKIEIFRHI 314 ++ + G P+ LA ++G +I R++ Sbjct: 105 -DVCDAWGRLPVDLAEEQGHRDIARYL 130 >6ACN-A nrPDB Length = 754 Score = 32.0 bits (71), Expect = 0.90, Method: Composition-based stats. Identities = 39/225 (17%), Positives = 71/225 (31%), Gaps = 53/225 (23%) Query: 10 FRLETSDGDEEGNAEVNKGKQEPPPMESPFQREDRNSSPQIKVNLNFIKRPPKNTSAPSQ 69 F+LE D DE AE + G+ + P+ +R + ++ Sbjct: 495 FKLEAPDADELPRAEFDPGQ------------DTYQHPPKDSSG----QRVDVSPTSQRL 538 Query: 70 QEPDRFDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEG---------STGKTC 120 Q + FD+ ++L L ++ K TD G Sbjct: 539 QLLEPFDK---------WDGKDLEDLQILIKVKGKCTTDHISAAGPWLKFRGHLDNISNN 589 Query: 121 LMKAVLNLQDGVNACIM--PLLQIDKDSGNPKLLVNAQCT-----DEFY-QGHSALHIAI 172 L+ +N+++ + + + DE Y +G S H A+ Sbjct: 590 LLIGAINIENRKANSVRNAVTQEFGPVPDTARYYKQHGIRWVVIGDENYGEGSSREHSAL 649 Query: 173 EKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLA 217 E R L ++ ++ A +H + G LPL+ A Sbjct: 650 EPRHLGGRAIITKSFARIH-----------ETNLKKQGLLPLTFA 683 >1DCQ-A nrPDB Length = 278 Score = 32.0 bits (71), Expect = 1.0, Method: Composition-based stats. Identities = 34/201 (16%), Positives = 67/201 (33%), Gaps = 39/201 (19%) Query: 32 PPPMESPFQREDRNSSPQIKVNLNFIKRPPKNTSAPSQQEPDRFDRDRLFSVV-SRGVPE 90 P P R+D ++ ++ + ++ +T+A + +F ++ + Sbjct: 97 PNPGSDMIARKDYITAKYMERR--YARKKHADTAAKLHSLCEAVKTRDIFGLLQAYADGV 154 Query: 91 ELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPK 150 +LT + + T S +T L +Q+ N +DK +G Sbjct: 155 DLTEKIPLANGHEPDETALHLAVRSVDRTSLHIVDFLVQNSGN--------LDKQTG--- 203 Query: 151 LLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFG 210 +G +ALH + +C+KLL+ A + + G Sbjct: 204 ------------KGSTALHYCCLTDNAECLKLLLRGKASIEIAN-------------ESG 238 Query: 211 ELPLSLAACTKQWDVVTYLLE 231 E PL +A K L + Sbjct: 239 ETPLDIAKRLKHEHCEELLTQ 259 >2QSG-A nrPDB Length = 533 Score = 30.9 bits (68), Expect = 2.1, Method: Composition-based stats. Identities = 13/76 (17%), Positives = 32/76 (42%), Gaps = 4/76 (5%) Query: 266 LVIHMYDGLLQMGARLCP--TVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQREFSGPY 323 ++D + + P +E++ H L P +A E + R+++ + Sbjct: 216 FWCEVWDKFSKKWITVDPVNLKTIEQVRLHSKLAPKGVACCERN--MLRYVIAYDRKYGC 273 Query: 324 QPLSRKFTEWCYGPVR 339 + ++R++ +W VR Sbjct: 274 RDVTRRYAQWMNSKVR 289 >6DJS-A nrPDB Length = 676 Score = 30.1 bits (66), Expect = 3.3, Method: Composition-based stats. Identities = 20/88 (22%), Positives = 31/88 (35%), Gaps = 18/88 (20%) Query: 157 CTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSL 216 Y G +AL +A+ L+ +LL++ +L G L L Sbjct: 72 VNCVDYMGQNALQLAVGNEHLEVTELLLKKE---NLARIGDA---------------LLL 113 Query: 217 AACTKQWDVVTYLLENPHQPASLEATDS 244 A +V +L +P AS T S Sbjct: 114 AISKGYVRIVEAILNHPGFAASKRLTLS 141 >4P5Q-A nrPDB Length = 361 Score = 30.1 bits (66), Expect = 3.4, Method: Composition-based stats. Identities = 12/58 (20%), Positives = 30/58 (51%), Gaps = 9/58 (15%) Query: 18 DEEGNAEVNKGKQEPPPMESPFQ---------REDRNSSPQIKVNLNFIKRPPKNTSA 66 +++ V++G + PPPM+ P ++DRN+ P+ + ++ + + +N + Sbjct: 244 NQDVIKAVDEGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGS 301 >6N4I-A nrPDB Length = 288 Score = 29.7 bits (65), Expect = 5.0, Method: Composition-based stats. Identities = 42/261 (16%), Positives = 92/261 (35%), Gaps = 59/261 (22%) Query: 391 SRFFFNFACYLVYMFIFTVVAYHQPSLDQPAIPSSKATFGESMLLLGHILILLGGIYLLL 450 S FF F YL+ + + H P ++ +++L +G++ ++ + Sbjct: 29 SSFFTKFIIYLIVLNTLFMAMEHHPMTEE----------FKNVLAIGNL------VFTGI 72 Query: 451 GQLWYFWRRRLFIWISFMDSYFEILFLLQALLTVLSQV-LRFMETEWYLPLLVLSLVLGW 509 + R + F D + L +L+ LS V L + E L L Sbjct: 73 FAIEIILRIYVHRISFFKDPWS----LFDSLIVTLSLVELFLADVEGLSVLRSFRL---- 124 Query: 510 LNLLYYTRGF-QHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVSLSREARSPKAP 568 L + Q I S +I ++ +L + + +F + FA+ L Sbjct: 125 LRVFRLVTAVPQMRKIVSALIS--VIPGMLSVIALMTLFFYIFAIMATQL---------- 172 Query: 569 EDNNSTVTEQPTVGQEEEPAPYRSILDASLELFKF----TIGMGELA-FQEQLRFRGVVL 623 E P + ++ ++ LF+ + MG + E + V Sbjct: 173 -------------FGERFPEWFGTLGESFYTLFQVMTLESWSMGIVRPLMEVYPYAWVF- 218 Query: 624 LLLLAYVLLTYVLLLNMLIAL 644 + ++ + +++N+++A+ Sbjct: 219 --FIPFIFVVTFVMINLVVAI 237 >4E68-A nrPDB Length = 596 Score = 28.9 bits (63), Expect = 9.3, Method: Composition-based stats. Identities = 13/74 (17%), Positives = 33/74 (44%), Gaps = 1/74 (1%) Query: 41 REDRNSSPQIKVNLNFIKRPPKNTSAPSQQEPDRFDRDRL-FSVVSRGVPEELTGLLEYL 99 ++D + + + + ++ N + ++Q+ + ++ + R + EL GLL + Sbjct: 43 QDDFDFNYKTLKSQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAM 102 Query: 100 RWNSKYLTDSAYTE 113 + K LTD + Sbjct: 103 EYVQKTLTDEELAD 116 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.129 0.340 Lambda K H 0.267 0.0393 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 26,844,762 Number of Sequences: 36641 Number of extensions: 1019999 Number of successful extensions: 3237 Number of sequences better than 10.0: 87 Number of HSP's better than 10.0 without gapping: 104 Number of HSP's successfully gapped in prelim test: 32 Number of HSP's that attempted gapping in prelim test: 2476 Number of HSP's gapped (non-prelim): 292 length of query: 761 length of database: 10,336,785 effective HSP length: 105 effective length of query: 656 effective length of database: 6,489,480 effective search space: 4257098880 effective search space used: 4257098880 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 63 (28.9 bits)