BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9UQ80 (394 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2Q8K-A nrPDB 812 0.0 2V6C-A nrPDB 729 0.0 4IPA-A nrPDB 186 2e-47 1QZY-A nrPDB 110 1e-24 5LYW-A nrPDB 109 2e-24 1XGN-A nrPDB 103 1e-22 3FMR-A nrPDB 80 1e-15 5APN-x nrPDB 68 5e-12 3TAV-A nrPDB 56 2e-08 1O0X-A nrPDB 51 9e-07 4FUK-A nrPDB 49 4e-06 1QXW-A nrPDB 48 9e-06 4A6V-A nrPDB 47 2e-05 2BWY-A nrPDB 44 1e-04 3MR1-A nrPDB 43 2e-04 3TB5-A nrPDB 43 2e-04 4FO7-A nrPDB 42 4e-04 4PV4-A nrPDB 42 7e-04 4IU6-A nrPDB 41 0.001 2B3K-A nrPDB 40 0.001 5WZE-A nrPDB 40 0.002 3S6B-A nrPDB 37 0.011 6MRF-A nrPDB 37 0.015 3IG4-A nrPDB 36 0.024 2ZSG-A nrPDB 34 0.094 3ROR-A nrPDB 33 0.25 3WIR-A nrPDB 33 0.27 4KM3-A nrPDB 32 0.45 5XM3-B nrPDB 29 3.8 6HGC-B nrPDB 28 9.5 >2Q8K-A nrPDB Length = 401 Score = 812 bits (2097), Expect = 0.0, Method: Compositional matrix adjust. Identities = 393/393 (100%), Positives = 393/393 (100%) Query: 2 SGEDEQQEQTIAEDLVVTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETG 61 SGEDEQQEQTIAEDLVVTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETG Sbjct: 9 SGEDEQQEQTIAEDLVVTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETG 68 Query: 62 KIFKKEKEMKKGIAFPTSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANV 121 KIFKKEKEMKKGIAFPTSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANV Sbjct: 69 KIFKKEKEMKKGIAFPTSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANV 128 Query: 122 AHTFVVDVAQGTQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTP 181 AHTFVVDVAQGTQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTP Sbjct: 129 AHTFVVDVAQGTQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTP 188 Query: 182 IEGMLSHQLKQHVIDGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDAG 241 IEGMLSHQLKQHVIDGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDAG Sbjct: 189 IEGMLSHQLKQHVIDGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDAG 248 Query: 242 QRTTIYKRDPSKQYGLKMKTSRAFFSEVERRFDAMPFTLRAFEDEKKARMGVVECAKHEL 301 QRTTIYKRDPSKQYGLKMKTSRAFFSEVERRFDAMPFTLRAFEDEKKARMGVVECAKHEL Sbjct: 249 QRTTIYKRDPSKQYGLKMKTSRAFFSEVERRFDAMPFTLRAFEDEKKARMGVVECAKHEL 308 Query: 302 LQPFNVLYEKEGEFVAQFKFTVLLMPNGPMRITSGPFEPDLYKSEMEVQDAELKALLQSS 361 LQPFNVLYEKEGEFVAQFKFTVLLMPNGPMRITSGPFEPDLYKSEMEVQDAELKALLQSS Sbjct: 309 LQPFNVLYEKEGEFVAQFKFTVLLMPNGPMRITSGPFEPDLYKSEMEVQDAELKALLQSS 368 Query: 362 ASRKTQKKKKKKASKTAENATSGETLEENEAGD 394 ASRKTQKKKKKKASKTAENATSGETLEENEAGD Sbjct: 369 ASRKTQKKKKKKASKTAENATSGETLEENEAGD 401 >2V6C-A nrPDB Length = 353 Score = 729 bits (1881), Expect = 0.0, Method: Compositional matrix adjust. Identities = 348/353 (98%), Positives = 351/353 (99%) Query: 8 QEQTIAEDLVVTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKKE 67 +EQTIAEDLVVTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKKE Sbjct: 1 EEQTIAEDLVVTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKKE 60 Query: 68 KEMKKGIAFPTSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVV 127 KEMKKGIAFPTSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFV+ Sbjct: 61 KEMKKGIAFPTSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVI 120 Query: 128 DVAQGTQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGMLS 187 VAQGTQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGMLS Sbjct: 121 GVAQGTQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGMLS 180 Query: 188 HQLKQHVIDGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDAGQRTTIY 247 HQLKQHVIDGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDAGQRTTIY Sbjct: 181 HQLKQHVIDGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDAGQRTTIY 240 Query: 248 KRDPSKQYGLKMKTSRAFFSEVERRFDAMPFTLRAFEDEKKARMGVVECAKHELLQPFNV 307 KRDPSKQYGLKMKTSRAFFSEVERRFDAMPF LRAFEDEKKARMGVVECAKHELLQPFNV Sbjct: 241 KRDPSKQYGLKMKTSRAFFSEVERRFDAMPFALRAFEDEKKARMGVVECAKHELLQPFNV 300 Query: 308 LYEKEGEFVAQFKFTVLLMPNGPMRITSGPFEPDLYKSEMEVQDAELKALLQS 360 LYE+EGEFVAQFKFTVLLMPNGPMRITSGPFEPDLYKSEMEVQDAELKALLQS Sbjct: 301 LYEREGEFVAQFKFTVLLMPNGPMRITSGPFEPDLYKSEMEVQDAELKALLQS 353 >4IPA-A nrPDB Length = 423 Score = 186 bits (471), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 119/373 (31%), Positives = 197/373 (52%), Gaps = 33/373 (8%) Query: 17 VVTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAF 76 V+TKYK I+ +VL + + G ++ +CE+GD ++ EE K+++ +K+ KG + Sbjct: 25 VLTKYKTAAQISEKVLAEVSKLCVPGAKIIDICEQGDKLMEEELSKVYR-DKKTNKGFSH 83 Query: 77 PTSISVNNCVCHFSPLKSDQDYILKE---GDLVKIDLGVHVDGFIANVAHTFVVDVAQGT 133 PT++S + ++PL+SD+ E G+ +KI LG +DG+ V T V A Sbjct: 84 PTTVSPAAFITPYTPLRSDEKEAATEIQPGEPIKIQLGAQIDGYGTIVCDTIVAKNANDP 143 Query: 134 QVT-GRKADVIKAAHLCAEAALRL--------------------VKPGNQNTQVTEAWNK 172 V GR+AD+ A + E LRL VKP +Q +++ K Sbjct: 144 DVIEGRQADLFLATYYANEVLLRLMVPPGLLATGTDEEKAKAAAVKPPSQ-AKISSLLEK 202 Query: 173 VAHSFNCTPIEGMLSHQLKQHVIDGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSS 232 VA +++C IE S ++ I+G+K II +P + K + EV +V+ V+V S Sbjct: 203 VAKAYDCNIIESTTSWLFDKNEIEGKKKIILSPGENIKGEGVP---EVGDVWGVEVGCSL 259 Query: 233 GEGKAKDAGQRTTIYKRDPSKQYGLKMKTSRAFFSEVERRFDAMPFTLRAFEDEKKARMG 292 G GK K QR T+++R + Y LK TSR +SEV+++F PF+LR EDE+ A+ G Sbjct: 260 GSGKVKQFEQRATLHRRT-NNTYALKRPTSRKIYSEVQKKFGTFPFSLRQLEDERDAKSG 318 Query: 293 VVECAKHELLQPFNVLYEKEGEFVAQFKFTVLLMPNGPMRITSGPFEPDL--YKSEMEVQ 350 V+EC + + + + V +K+ V + T+ + NG RI GP DL +K++ +++ Sbjct: 319 VIECVRGGVFRQYEVTGDKDNAPVCRLLTTIAITKNGITRI-GGPPAWDLSKFKTDKKIE 377 Query: 351 DAELKALLQSSAS 363 D E+ +L+ S Sbjct: 378 DEEILKILEQPLS 390 >1QZY-A nrPDB Length = 478 Score = 110 bits (275), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 79/305 (25%), Positives = 136/305 (44%), Gaps = 18/305 (5%) Query: 28 ANRVLRSLVEAS-SSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFPTSISVNNCV 86 A+R +R V + G++++ +CEK +E+ + KE + G+AFPT S+NNC Sbjct: 175 AHRQVRKYVMSWIKPGMTMIEICEK-----LEDCSRKLIKENGLNAGLAFPTGCSLNNCA 229 Query: 87 CHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGTQVTGRKADVIKAA 146 H++P D +L+ D+ KID G H+ G I + A T + T + K D Sbjct: 230 AHYTPNAGDTT-VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVK-DATNTG 287 Query: 147 HLCAEAALRLVKPGNQNTQVTEAWNKV--AHSFNCTPIEGMLSHQLKQHVIDGEKTIIQN 204 CA +RL G +V E++ ++ PI + H + Q+ I KT+ Sbjct: 288 IKCAGIDVRLCDVGEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTV--- 344 Query: 205 PTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDAGQRTTIYKRDPSKQYGLKMKTSRA 264 K E E EVYA++ S+G+G D + + K +++ ++ Sbjct: 345 ---PIIKGGEATRMEEGEVYAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKH 401 Query: 265 FFSEVERRFDAMPFTLRAFE--DEKKARMGVVECAKHELLQPFNVLYEKEGEFVAQFKFT 322 + + F + F R + E K M + ++ P+ L + +G + AQF+ T Sbjct: 402 LLNVINENFGTLAFCRRWLDRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHT 461 Query: 323 VLLMP 327 +LL P Sbjct: 462 ILLRP 466 >5LYW-A nrPDB Length = 378 Score = 109 bits (273), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 79/305 (25%), Positives = 136/305 (44%), Gaps = 18/305 (5%) Query: 28 ANRVLRSLVEAS-SSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFPTSISVNNCV 86 A+R +R V + G++++ +CEK +E+ + KE + G+AFPT S+NNC Sbjct: 69 AHRQVRKYVMSWIKPGMTMIEICEK-----LEDCSRKLIKENGLNAGLAFPTGCSLNNCA 123 Query: 87 CHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGTQVTGRKADVIKAA 146 H++P D +L+ D+ KID G H+ G I + A T + T + K D Sbjct: 124 AHYTPNAGDTT-VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVK-DATNTG 181 Query: 147 HLCAEAALRLVKPGNQNTQVTEAWNKV--AHSFNCTPIEGMLSHQLKQHVIDGEKTIIQN 204 CA +RL G +V E++ ++ PI + H + Q+ I KT+ Sbjct: 182 IKCAGIDVRLCDVGEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTV--- 238 Query: 205 PTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDAGQRTTIYKRDPSKQYGLKMKTSRA 264 K E E EVYA++ S+G+G D + + K +++ ++ Sbjct: 239 ---PIVKGGEATRMEEGEVYAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKH 295 Query: 265 FFSEVERRFDAMPFTLRAFE--DEKKARMGVVECAKHELLQPFNVLYEKEGEFVAQFKFT 322 + + F + F R + E K M + ++ P+ L + +G + AQF+ T Sbjct: 296 LLNVINENFGTLAFCRRWLDRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHT 355 Query: 323 VLLMP 327 +LL P Sbjct: 356 ILLRP 360 >1XGN-A nrPDB Length = 295 Score = 103 bits (258), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 75/305 (24%), Positives = 147/305 (48%), Gaps = 33/305 (10%) Query: 25 GDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFPTSISVNN 84 G+IA +V ++ + G+ +L L E + MIME GK AFP ++S+N Sbjct: 10 GEIAKKVREKAIKLARPGMLLLELAESIEKMIMELGGKP-----------AFPVNLSINE 58 Query: 85 CVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGTQVTGRKADVIK 144 H++P K D +LKEGD +KID+GVH+DGFIA+ A T +V + ++++ Sbjct: 59 IAAHYTPYKGDTT-VLKEGDYLKIDVGVHIDGFIADTAVT--------VRVGMEEDELME 109 Query: 145 AAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGMLSHQLKQHVIDGEKTIIQN 204 AA AA+ + + G + ++ +A PI + H+++++ + +I Sbjct: 110 AAKEALNAAISVARAGVEIKELGKAIENEIRKRGFKPIVNLSGHKIERYKLHAGISI--- 166 Query: 205 PTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDAGQRTT-IYKRDPSKQYGLKMKTSR 263 + H+ + +V+A++ + G G+ + +Y RD +++ +R Sbjct: 167 --PNIYRPHDNYVLKEGDVFAIEPFATIGAGQVIEVPPTLIYMYVRDVP----VRVAQAR 220 Query: 264 AFFSEVERRFDAMPFTLRAFED---EKKARMGVVECAKHELLQPFNVLYEKEGEFVAQFK 320 ++++R + +PF R ++ E + ++ + K + + VL E VAQF+ Sbjct: 221 FLLAKIKREYGTLPFAYRWLQNDMPEGQLKLALKTLEKAGAIYGYPVLKEIRNGIVAQFE 280 Query: 321 FTVLL 325 T+++ Sbjct: 281 HTIIV 285 >3FMR-A nrPDB Length = 358 Score = 80.5 bits (197), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 78/318 (24%), Positives = 131/318 (41%), Gaps = 54/318 (16%) Query: 42 GVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFPTSISVNNCVCHFSPLKSDQDYILK 101 G+++L + I + T + K E+ GI FP +S+N+C H++ +QD +LK Sbjct: 69 GITLLEIVRS----IEDSTRTLLKGER--NNGIGFPAGMSMNSCAAHYTVNPGEQDIVLK 122 Query: 102 EGDLVKIDLGVHVDGFIANVAHT---------FVVDVAQGTQVTGRKADVIKAAHLCAEA 152 E D++KID G H DG I + A T +V +GT+ TG K+ Sbjct: 123 EDDVLKIDFGTHSDGRIMDSAFTVAFKENLEPLLVAAREGTE-TGIKS---------LGV 172 Query: 153 ALRLVKPGNQNTQVTEAWNK--VAHSFNCTPIEGMLSHQLKQHVIDGEKTIIQNPTDQQK 210 +R+ G +V ++ + PI + H + Q I G +I Sbjct: 173 DVRVCDIGRDINEVISSYEVEIGGRMWPIRPISDLHGHSISQFRIHGGISI------PAV 226 Query: 211 KDHEKAEFEVHEVYAVDVLVSSGEGKAKDAGQRTTIYKRDPSKQYGLKMKTSRAFFSE-- 268 + + + YAV+ ++G+G D R P + L SR F++ Sbjct: 227 NNRDTTRIKGDSFYAVETFATTGKGSIDD---------RPPCSHFVLNTYKSRKLFNKDL 277 Query: 269 ------VERRFDAMPFTLRAFEDEKKARMGVVECAK----HELLQPFNVLYEKEGEFVAQ 318 V+ +PF+ R + + G ++ LL P+ L + +G VAQ Sbjct: 278 IKVYEFVKDSLGTLPFSPRHLDYYGLVKGGSLKSVNLLTMMGLLTPYPPLNDIDGCKVAQ 337 Query: 319 FKFTVLLMPNGPMRITSG 336 F+ TV L +G +T G Sbjct: 338 FEHTVYLSEHGKEVLTRG 355 >5APN-x nrPDB Length = 616 Score = 68.2 bits (165), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 88/390 (22%), Positives = 154/390 (39%), Gaps = 112/390 (28%) Query: 1 MSGEDEQ---QEQTIAEDLVVTKYKMGGDIANRVLR---SLVEASSSG------VSVLSL 48 +S ED Q +++ I ++ V+ KY+ G IA L+ SL+ S ++V L Sbjct: 28 ISHEDTQILLKDKNILQESVLNKYRTAGQIAQTALKYVTSLINDSYHSKTTQRQLTVPEL 87 Query: 49 CEKGDAMIMEETGKIFKKEKEMKKGIAFPTSISVNNCVCHFSPLKSDQDYIL-------- 100 C D+ I+ + +K K ++GIA PT+I ++ + P D +L Sbjct: 88 CLLTDSFILTRLEQYYKN-KVNERGIAIPTTIDIDQISGGWCPEIDDTQNLLNWNKGKDS 146 Query: 101 ----------KEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGT----QVTG--------- 137 + GDLVKI LGVH+DG+ + V+HT V+ T Q TG Sbjct: 147 TFASSVTGTLRPGDLVKITLGVHIDGYTSEVSHTMVIYPVDETKPILQPTGPLLGGKADA 206 Query: 138 -----RKADVIKAAHLCA------EAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGML 186 + + A CA A+L G + + +A S+NC + G Sbjct: 207 VAAAHIAMETVVALLACALTPEKLPASLGGTSSGITGQLIRTIVDTIARSYNCGVVPGSR 266 Query: 187 SHQLKQHVIDGEKTIIQNPTDQ---QKKDHEKAEF------------------------- 218 ++++ + + I+ + + H++A+ Sbjct: 267 VRRIRRFLAGQNEGIVAEREYKGVVWTESHQEADLLSNTDAKDLTVVDRGQSTPFTNVSA 326 Query: 219 --------EVHEVYAVDVLVSSGE-----------------GKAKDAGQ---RTTIYKRD 250 + EVY +D+ ++S E GK+ AG+ R Y RD Sbjct: 327 IPSDDFVVQSGEVYLIDLKMASLEHCTKKGLVTLETVDSYTGKSHKAGELIARPGAYVRD 386 Query: 251 PSKQYGLKMKTSRAFFSEVERRFDAMPFTL 280 ++ + LK+KTSR ++++++ PF L Sbjct: 387 FAQTHILKLKTSRQLLTKIDKQ-GVYPFKL 415 >3TAV-A nrPDB Length = 286 Score = 56.2 bits (134), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 49/147 (33%), Positives = 74/147 (50%), Gaps = 15/147 (10%) Query: 25 GDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFPTSI--SV 82 G I L ++ +A+ +GVS L L + +++I E G + FP SI SV Sbjct: 47 GSIVGAALVAVRDAAKAGVSTLELDQVAESVI-REAGAV----PSFLGYHGFPASICSSV 101 Query: 83 NNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGTQVTGRKADV 142 N+ V H P + +L +GDLV ID G +DG+ + A TF V GT + +A + Sbjct: 102 NDQVVHGIPSAT---AVLADGDLVSIDCGAILDGWHGDSAWTFAV----GTVIPSDEA-L 153 Query: 143 IKAAHLCAEAALRLVKPGNQNTQVTEA 169 +A L EA + + PGN+ T V+ A Sbjct: 154 SEATRLSMEAGIAAMIPGNRLTDVSHA 180 >1O0X-A nrPDB Length = 262 Score = 50.8 bits (120), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 31/120 (25%), Positives = 56/120 (46%), Gaps = 8/120 (6%) Query: 73 GIAFPTSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQG 132 G + T +SVN V H PLK + + KEGD+V +D+G G + A T++V Sbjct: 74 GYKYATCVSVNEEVVHGLPLK---EKVFKEGDIVSVDVGAVYQGLYGDAAVTYIVG---- 126 Query: 133 TQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGMLSHQLKQ 192 + R ++++ E A++++KPG + V+ + S I + H + + Sbjct: 127 -ETDERGKELVRVTREVLEKAIKMIKPGIRLGDVSHCIQETVESVGFNVIRDYVGHGVGR 185 >4FUK-A nrPDB Length = 337 Score = 48.9 bits (115), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 34/120 (28%), Positives = 56/120 (46%), Gaps = 19/120 (15%) Query: 75 AFPTSI--SVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQG 132 FP S+ SVN +CH P + L+EGD++ ID+ +++GF ++ T + Sbjct: 121 GFPKSVCTSVNEVICHGIPDSRE----LEEGDILNIDVSSYLNGFHGDLNETVFI----- 171 Query: 133 TQVTGRKAD----VIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGMLSH 188 GR D ++ AA+ C A + +VKP QV +A A + C+ + H Sbjct: 172 ----GRPDDDSVRLVHAAYECLCAGIGVVKPEALYKQVGDAIEACASQYQCSVVRTYTGH 227 >1QXW-A nrPDB Length = 252 Score = 47.8 bits (112), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 37/115 (32%), Positives = 55/115 (47%), Gaps = 10/115 (8%) Query: 76 FP--TSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGT 133 FP T ISVN V H P K +++EGDLV ID+ +G+ A+ +FVV G Sbjct: 62 FPGQTCISVNEEVAHGIPSKR----VIREGDLVNIDVSALKNGYYADTGISFVV----GE 113 Query: 134 QVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGMLSH 188 K V A + E A+ VKPG + + + +A + A + I+ + H Sbjct: 114 SDDPMKQKVCDVATMAFENAIAKVKPGTKLSNIGKAVHNTARQNDLKVIKNLTGH 168 >4A6V-A nrPDB Length = 265 Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 35/100 (35%), Positives = 49/100 (49%), Gaps = 10/100 (10%) Query: 75 AFPTS--ISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQG 132 +P S IS+N VCH P D +LK+GD+V ID+ V DGF + + F+V Sbjct: 64 GYPKSVCISINEVVCHGIP---DDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVG---K 117 Query: 133 TQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNK 172 + G + I L ALR+VKPG ++ A K Sbjct: 118 PTIMGERLCRITQESL--YLALRMVKPGINLREIGAAIQK 155 >2BWY-A nrPDB Length = 440 Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 27/102 (26%), Positives = 51/102 (50%), Gaps = 13/102 (12%) Query: 71 KKGIAFPTSISV-----NNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTF 125 + G +P+ ++ N C+ H++ + + +++GDLV ID G G+ ++ TF Sbjct: 221 RHGARYPSYNTIVGSGENGCILHYTENECE----MRDGDLVLIDAGCEYKGYAGDITRTF 276 Query: 126 VVDVAQGTQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVT 167 V+ + TQ D++ + E +LRL +PG +VT Sbjct: 277 PVN-GKFTQAQREIYDIVLES---LETSLRLYRPGTSILEVT 314 >3MR1-A nrPDB Length = 252 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 33/121 (27%), Positives = 55/121 (45%), Gaps = 13/121 (10%) Query: 75 AFPTSI--SVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVV-DVAQ 131 FP SI S+N+ VCH P D LK GD+V ID+ V +DG+ + + + V DVA Sbjct: 66 GFPKSICTSINHVVCHGIP----NDKPLKNGDIVNIDVTVILDGWYGDTSRMYYVGDVAI 121 Query: 132 GTQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGMLSHQLK 191 + +I+ + + +V+PG + + A A N + + H + Sbjct: 122 ------KPKRLIQVTYDAMMKGIEVVRPGAKLGDIGYAIQSYAEKHNYSVVRDYTGHGIG 175 Query: 192 Q 192 + Sbjct: 176 R 176 >3TB5-A nrPDB Length = 264 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 25/75 (33%), Positives = 42/75 (56%), Gaps = 6/75 (8%) Query: 72 KGIAFPTSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQ 131 +G + T S+N+ +CH P K +LK+GDL+K+D+ V + G I++ ++V V + Sbjct: 61 EGYKYATCCSINDEICHGFPRKK----VLKDGDLIKVDMCVDLKGAISDSCWSYV--VGE 114 Query: 132 GTQVTGRKADVIKAA 146 T R +V K A Sbjct: 115 STPEIDRLMEVTKKA 129 >4FO7-A nrPDB Length = 280 Score = 42.0 bits (97), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 42/159 (26%), Positives = 68/159 (42%), Gaps = 15/159 (9%) Query: 18 VTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFP 77 + K ++ G +A VL + E GV+ L I+ E K K FP Sbjct: 11 IEKMRIAGRLAAEVLEMIGEHIKPGVTTEELDRICHDYIVNEQ-KAIPAPLNYK---GFP 66 Query: 78 TSI--SVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGTQV 135 SI S+N+ VCH P + LKEGD++ +D+ V DG+ + + F+ V + + Sbjct: 67 KSICTSINHVVCHGIP----NEKPLKEGDILNVDITVIKDGYHGDTSKMFL--VGKTPEW 120 Query: 136 TGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVA 174 R + + C + +V+PG + E K A Sbjct: 121 ADRLCQITQE---CMYKGISVVRPGAHLGDIGEIIQKHA 156 >4PV4-A nrPDB Length = 445 Score = 41.6 bits (96), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 29/105 (27%), Positives = 51/105 (48%), Gaps = 17/105 (16%) Query: 71 KKGIAFPTSISV-----NNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTF 125 + G +P ++ N C+ H++ + + L++GDLV ID G G+ ++ TF Sbjct: 219 RHGARYPAYNTIVGGGENGCILHYTENECE----LRDGDLVLIDAGCEYRGYAGDITRTF 274 Query: 126 VVDVAQGTQVTGRKA--DVIKAAHLCAEAALRLVKPGNQNTQVTE 168 V+ G ++A D++ AA +L L +PG +VTE Sbjct: 275 PVN---GKFTPAQRAVYDIVLAA---INKSLTLFRPGTSIREVTE 313 >4IU6-A nrPDB Length = 384 Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust. Identities = 27/88 (30%), Positives = 46/88 (52%), Gaps = 13/88 (14%) Query: 76 FPTSI--SVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVV-DVAQG 132 FP S SVN +CH P + L+EGD+V +D+ ++ +G+ ++ TF V +V G Sbjct: 189 FPKSCCTSVNEVICHGIPDRRP----LQEGDIVNVDITLYRNGYHGDLNETFFVGEVDDG 244 Query: 133 TQVTGRKADVIKAAHLCAEAALRLVKPG 160 + +++ + C A+ VKPG Sbjct: 245 AR------KLVQTTYECLMQAIDAVKPG 266 >2B3K-A nrPDB Length = 329 Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust. Identities = 27/88 (30%), Positives = 46/88 (52%), Gaps = 13/88 (14%) Query: 76 FPTSI--SVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVV-DVAQG 132 FP S SVN +CH P + L+EGD+V +D+ ++ +G+ ++ TF V +V G Sbjct: 134 FPKSCCTSVNEVICHGIPDRRP----LQEGDIVNVDITLYRNGYHGDLNETFFVGEVDDG 189 Query: 133 TQVTGRKADVIKAAHLCAEAALRLVKPG 160 + +++ + C A+ VKPG Sbjct: 190 AR------KLVQTTYECLMQAIDAVKPG 211 >5WZE-A nrPDB Length = 452 Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust. Identities = 39/149 (26%), Positives = 68/149 (45%), Gaps = 23/149 (15%) Query: 30 RVLRSLVEASSSG-VSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIA-FPTSISV----- 82 +V+R E S+ + + +C G + E + E E +KG A P S+ Sbjct: 182 KVMRYAAEVSARAHIRAMEVCRPG----LFEYHLEAELEYEFRKGGAKMPAYGSIVAAGR 237 Query: 83 NNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGTQVTGRKA-- 140 N C+ H+ + D +K+GDL+ ID G +D + +++ TF A G +KA Sbjct: 238 NACILHYR----ENDAAIKDGDLILIDAGCEIDCYASDITRTF---PANGRFSPEQKAIY 290 Query: 141 DVIKAAHLCAEAALRLVKPGNQNTQVTEA 169 +++ A++ AA + PG + EA Sbjct: 291 ELVLEANM---AAFDYIAPGRHWNEAHEA 316 >3S6B-A nrPDB Length = 368 Score = 37.4 bits (85), Expect = 0.011, Method: Compositional matrix adjust. Identities = 27/88 (30%), Positives = 42/88 (47%), Gaps = 10/88 (11%) Query: 76 FPTSI--SVNNCVCHFSPLKSDQDY-ILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQG 132 FP S SVN VCH P DY LK GD++ ID+ V G +++ T+ V Sbjct: 162 FPKSCCTSVNEIVCHGIP-----DYRPLKSGDIINIDISVFYKGVHSDLNETYFVGDIND 216 Query: 133 TQVTGRKADVIKAAHLCAEAALRLVKPG 160 G+ ++++ + A++ KPG Sbjct: 217 VPKEGK--ELVETCYFSLMEAIKKCKPG 242 >6MRF-A nrPDB Length = 270 Score = 37.0 bits (84), Expect = 0.015, Method: Compositional matrix adjust. Identities = 22/55 (40%), Positives = 32/55 (58%), Gaps = 5/55 (9%) Query: 75 AFPTSI--SVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVV 127 AF SI SVN+ VCH P ++ ILK GD++ ID+ V DG+ + ++V Sbjct: 75 AFQHSICTSVNHVVCHGIP---SENKILKNGDILNIDVTVIKDGYHGDTNMMYIV 126 >3IG4-A nrPDB Length = 427 Score = 36.2 bits (82), Expect = 0.024, Method: Compositional matrix adjust. Identities = 29/101 (28%), Positives = 48/101 (47%), Gaps = 10/101 (9%) Query: 75 AFPTSISV--NNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQG 132 AF T ++ N V H+ D D ++ GDLV +DLG D + A++++TF A G Sbjct: 224 AFNTILASGKNATVLHYE----DNDAQIQNGDLVLLDLGAQKDYYNADISYTF---PANG 276 Query: 133 TQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKV 173 T + R+ + + ++KPG + + E KV Sbjct: 277 T-FSSRQKQIYNIVLNALKETTEIIKPGLKFAALNEHAKKV 316 >2ZSG-A nrPDB Length = 359 Score = 34.3 bits (77), Expect = 0.094, Method: Compositional matrix adjust. Identities = 39/147 (26%), Positives = 65/147 (44%), Gaps = 25/147 (17%) Query: 18 VTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFP 77 + K K +I+ R V+ +G + EK A ++E T + KE +G+AF Sbjct: 139 IEKIKQAIEISERAFLETVQQIRAG-----MTEKEIAALLEYTMR-----KEGAEGVAFD 188 Query: 78 TSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGTQVTG 137 T I + C P D +++ GD++ ID G + + A++ T VV + G Sbjct: 189 T-IVASGCRSAL-PHGKASDKVVERGDVIVIDFGATYENYCADI--TRVVSI-------G 237 Query: 138 RKADVIKAAHLCA----EAALRLVKPG 160 +D +K H E AL++ K G Sbjct: 238 EPSDEVKEVHSIVLEAQERALKIAKAG 264 >3ROR-A nrPDB Length = 291 Score = 32.7 bits (73), Expect = 0.25, Method: Compositional matrix adjust. Identities = 28/120 (23%), Positives = 49/120 (40%), Gaps = 7/120 (5%) Query: 6 EQQEQTIAEDLVVTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFK 65 E E + V+ K ++ G IA L +A + GV+ L +++ Sbjct: 41 EGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAY--- 97 Query: 66 KEKEMKKGIAFPTSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTF 125 KG S S+N +CH P + ++ +GD+V ID+ ++ G + TF Sbjct: 98 PSTLGYKGFPKSCSTSLNEVICHGIPDST----VITDGDIVNIDVTAYIGGVHGDTNATF 153 >3WIR-A nrPDB Length = 764 Score = 32.7 bits (73), Expect = 0.27, Method: Compositional matrix adjust. Identities = 16/40 (40%), Positives = 23/40 (57%) Query: 63 IFKKEKEMKKGIAFPTSISVNNCVCHFSPLKSDQDYILKE 102 I K+K+ K GIA T + +NN C+F+ D YI+ E Sbjct: 189 ITTKDKKYKVGIASSTKVLLNNQRCYFNRFTKDLGYIITE 228 >4KM3-A nrPDB Length = 286 Score = 32.0 bits (71), Expect = 0.45, Method: Compositional matrix adjust. Identities = 15/35 (42%), Positives = 23/35 (65%), Gaps = 4/35 (11%) Query: 76 FPTSISVNNCVCHFSPLKSDQDYILKEGDLVKIDL 110 + T S+N+ V H P + YILK+GDL+K+D+ Sbjct: 69 YATCCSLNDEVAHAFP----RHYILKDGDLLKVDM 99 >5XM3-B nrPDB Length = 90 Score = 28.9 bits (63), Expect = 3.8, Method: Compositional matrix adjust. Identities = 16/44 (36%), Positives = 24/44 (54%) Query: 327 PNGPMRITSGPFEPDLYKSEMEVQDAELKALLQSSASRKTQKKK 370 P P +I ++P + E+ QDA LKA+ + +A R Q KK Sbjct: 41 PGFPDKIKGSKYDPKHSEKELNKQDAALKAMEKRNAERVEQFKK 84 >6HGC-B nrPDB Length = 310 Score = 27.7 bits (60), Expect = 9.5, Method: Compositional matrix adjust. Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 3/63 (4%) Query: 56 IMEETGKIFKKEKEMKKGIAFPTSISVNNCVCH--FSPLKSDQDYILKEGDLVKIDLGVH 113 I+E T +IF K++E I F + N+C H S L + + L+ GD + L H Sbjct: 60 IVETTAEIFVKDEEAISSIFFAQQVVPNSCATHALLSVLLNCNENNLQLGDTLS-RLKTH 118 Query: 114 VDG 116 G Sbjct: 119 TKG 121 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2Q8K-A nrPDB 550 e-157 2V6C-A nrPDB 485 e-137 4IPA-A nrPDB 355 2e-98 5LYW-A nrPDB 336 1e-92 1QZY-A nrPDB 331 4e-91 1XGN-A nrPDB 288 3e-78 3FMR-A nrPDB 283 8e-77 5APN-x nrPDB 227 1e-59 4FO7-A nrPDB 173 1e-43 3MR1-A nrPDB 159 2e-39 4A6V-A nrPDB 158 4e-39 4FUK-A nrPDB 149 2e-36 1O0X-A nrPDB 143 1e-34 4IU6-A nrPDB 142 3e-34 2B3K-A nrPDB 142 3e-34 3TAV-A nrPDB 140 1e-33 1QXW-A nrPDB 138 6e-33 3TB5-A nrPDB 137 1e-32 5WZE-A nrPDB 108 4e-24 4PV4-A nrPDB 98 6e-21 2BWY-A nrPDB 98 9e-21 Sequences not found previously or not previously below threshold: 3ROR-A nrPDB 142 3e-34 6MRF-A nrPDB 138 5e-33 3S6B-A nrPDB 133 1e-31 4KM3-A nrPDB 97 1e-20 5CNX-A nrPDB 69 4e-12 3Q6D-A nrPDB 63 2e-10 1PV9-A nrPDB 59 2e-09 2ZSG-A nrPDB 59 2e-09 1WY2-A nrPDB 59 3e-09 5MC5-A nrPDB 54 8e-08 3IG4-A nrPDB 53 2e-07 4ZNG-C nrPDB 53 2e-07 5X49-A nrPDB 51 9e-07 3RVA-A nrPDB 44 7e-05 3L7G-A nrPDB 40 0.002 4ZWP-A nrPDB 37 0.012 4QR8-A nrPDB 34 0.082 1K3I-A nrPDB 31 0.94 4V4T-BD nrPDB 30 1.5 5EYT-A nrPDB 30 2.1 >2Q8K-A nrPDB Length = 401 Score = 550 bits (1416), Expect = e-157, Method: Composition-based stats. Identities = 393/393 (100%), Positives = 393/393 (100%) Query: 2 SGEDEQQEQTIAEDLVVTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETG 61 SGEDEQQEQTIAEDLVVTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETG Sbjct: 9 SGEDEQQEQTIAEDLVVTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETG 68 Query: 62 KIFKKEKEMKKGIAFPTSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANV 121 KIFKKEKEMKKGIAFPTSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANV Sbjct: 69 KIFKKEKEMKKGIAFPTSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANV 128 Query: 122 AHTFVVDVAQGTQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTP 181 AHTFVVDVAQGTQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTP Sbjct: 129 AHTFVVDVAQGTQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTP 188 Query: 182 IEGMLSHQLKQHVIDGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDAG 241 IEGMLSHQLKQHVIDGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDAG Sbjct: 189 IEGMLSHQLKQHVIDGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDAG 248 Query: 242 QRTTIYKRDPSKQYGLKMKTSRAFFSEVERRFDAMPFTLRAFEDEKKARMGVVECAKHEL 301 QRTTIYKRDPSKQYGLKMKTSRAFFSEVERRFDAMPFTLRAFEDEKKARMGVVECAKHEL Sbjct: 249 QRTTIYKRDPSKQYGLKMKTSRAFFSEVERRFDAMPFTLRAFEDEKKARMGVVECAKHEL 308 Query: 302 LQPFNVLYEKEGEFVAQFKFTVLLMPNGPMRITSGPFEPDLYKSEMEVQDAELKALLQSS 361 LQPFNVLYEKEGEFVAQFKFTVLLMPNGPMRITSGPFEPDLYKSEMEVQDAELKALLQSS Sbjct: 309 LQPFNVLYEKEGEFVAQFKFTVLLMPNGPMRITSGPFEPDLYKSEMEVQDAELKALLQSS 368 Query: 362 ASRKTQKKKKKKASKTAENATSGETLEENEAGD 394 ASRKTQKKKKKKASKTAENATSGETLEENEAGD Sbjct: 369 ASRKTQKKKKKKASKTAENATSGETLEENEAGD 401 >2V6C-A nrPDB Length = 353 Score = 485 bits (1248), Expect = e-137, Method: Composition-based stats. Identities = 348/353 (98%), Positives = 351/353 (99%) Query: 8 QEQTIAEDLVVTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKKE 67 +EQTIAEDLVVTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKKE Sbjct: 1 EEQTIAEDLVVTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKKE 60 Query: 68 KEMKKGIAFPTSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVV 127 KEMKKGIAFPTSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFV+ Sbjct: 61 KEMKKGIAFPTSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVI 120 Query: 128 DVAQGTQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGMLS 187 VAQGTQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGMLS Sbjct: 121 GVAQGTQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGMLS 180 Query: 188 HQLKQHVIDGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDAGQRTTIY 247 HQLKQHVIDGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDAGQRTTIY Sbjct: 181 HQLKQHVIDGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDAGQRTTIY 240 Query: 248 KRDPSKQYGLKMKTSRAFFSEVERRFDAMPFTLRAFEDEKKARMGVVECAKHELLQPFNV 307 KRDPSKQYGLKMKTSRAFFSEVERRFDAMPF LRAFEDEKKARMGVVECAKHELLQPFNV Sbjct: 241 KRDPSKQYGLKMKTSRAFFSEVERRFDAMPFALRAFEDEKKARMGVVECAKHELLQPFNV 300 Query: 308 LYEKEGEFVAQFKFTVLLMPNGPMRITSGPFEPDLYKSEMEVQDAELKALLQS 360 LYE+EGEFVAQFKFTVLLMPNGPMRITSGPFEPDLYKSEMEVQDAELKALLQS Sbjct: 301 LYEREGEFVAQFKFTVLLMPNGPMRITSGPFEPDLYKSEMEVQDAELKALLQS 353 >4IPA-A nrPDB Length = 423 Score = 355 bits (911), Expect = 2e-98, Method: Composition-based stats. Identities = 117/388 (30%), Positives = 201/388 (51%), Gaps = 31/388 (7%) Query: 1 MSGEDEQQEQTIAEDLVVTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEET 60 M+ E ++ + V+TKYK I+ +VL + + G ++ +CE+GD ++ EE Sbjct: 9 MATEKKEADNVAISVDVLTKYKTAAQISEKVLAEVSKLCVPGAKIIDICEQGDKLMEEEL 68 Query: 61 GKIFKKEKEMKKGIAFPTSISVNNCVCHFSPLKSDQDYI---LKEGDLVKIDLGVHVDGF 117 K+++ +K+ KG + PT++S + ++PL+SD+ ++ G+ +KI LG +DG+ Sbjct: 69 SKVYR-DKKTNKGFSHPTTVSPAAFITPYTPLRSDEKEAATEIQPGEPIKIQLGAQIDGY 127 Query: 118 IANVAHTFVVDVAQGTQVT-GRKADVIKAAHLCAEAALRLVKPGNQNT------------ 164 V T V A V GR+AD+ A + E LRL+ P Sbjct: 128 GTIVCDTIVAKNANDPDVIEGRQADLFLATYYANEVLLRLMVPPGLLATGTDEEKAKAAA 187 Query: 165 -------QVTEAWNKVAHSFNCTPIEGMLSHQLKQHVIDGEKTIIQNPTDQQKKDHEKAE 217 +++ KVA +++C IE S ++ I+G+K II +P + K + Sbjct: 188 VKPPSQAKISSLLEKVAKAYDCNIIESTTSWLFDKNEIEGKKKIILSPGENIKGEGVP-- 245 Query: 218 FEVHEVYAVDVLVSSGEGKAKDAGQRTTIYKRDPSKQYGLKMKTSRAFFSEVERRFDAMP 277 EV +V+ V+V S G GK K QR T+++R + Y LK TSR +SEV+++F P Sbjct: 246 -EVGDVWGVEVGCSLGSGKVKQFEQRATLHRRT-NNTYALKRPTSRKIYSEVQKKFGTFP 303 Query: 278 FTLRAFEDEKKARMGVVECAKHELLQPFNVLYEKEGEFVAQFKFTVLLMPNGPMRITSGP 337 F+LR EDE+ A+ GV+EC + + + + V +K+ V + T+ + NG RI GP Sbjct: 304 FSLRQLEDERDAKSGVIECVRGGVFRQYEVTGDKDNAPVCRLLTTIAITKNGITRI-GGP 362 Query: 338 FEPDL--YKSEMEVQDAELKALLQSSAS 363 DL +K++ +++D E+ +L+ S Sbjct: 363 PAWDLSKFKTDKKIEDEEILKILEQPLS 390 >5LYW-A nrPDB Length = 378 Score = 336 bits (861), Expect = 1e-92, Method: Composition-based stats. Identities = 82/337 (24%), Positives = 149/337 (44%), Gaps = 19/337 (5%) Query: 5 DEQQEQTIAEDLVVTKYKMGGDIANRVLRSLVEAS-SSGVSVLSLCEKGDAMIMEETGKI 63 +E++ A + + ++ + A+R +R V + G++++ +CEK +E+ + Sbjct: 47 EEKKALDQASEEIWNDFREAAE-AHRQVRKYVMSWIKPGMTMIEICEK-----LEDCSRK 100 Query: 64 FKKEKEMKKGIAFPTSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAH 123 KE + G+AFPT S+NNC H++P D +L+ D+ KID G H+ G I + A Sbjct: 101 LIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTT-VLQYDDICKIDFGTHISGRIIDCAF 159 Query: 124 TFVVDVAQGTQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKV--AHSFNCTP 181 T + T + K D CA +RL G +V E++ ++ P Sbjct: 160 TVTFNPKYDTLLKAVK-DATNTGIKCAGIDVRLCDVGEAIQEVMESYEVEIDGKTYQVKP 218 Query: 182 IEGMLSHQLKQHVIDGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDAG 241 I + H + Q+ I KT+ K E E EVYA++ S+G+G D Sbjct: 219 IRNLNGHSIGQYRIHAGKTV------PIVKGGEATRMEEGEVYAIETFGSTGKGVVHDDM 272 Query: 242 QRTTIYKRDPSKQYGLKMKTSRAFFSEVERRFDAMPFTLRAFE--DEKKARMGVVECAKH 299 + + K +++ ++ + + F + F R + E K M + Sbjct: 273 ECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWLDRLGESKYLMALKNLCDL 332 Query: 300 ELLQPFNVLYEKEGEFVAQFKFTVLLMPNGPMRITSG 336 ++ P+ L + +G + AQF+ T+LL P ++ G Sbjct: 333 GIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRG 369 >1QZY-A nrPDB Length = 478 Score = 331 bits (847), Expect = 4e-91, Method: Composition-based stats. Identities = 82/337 (24%), Positives = 149/337 (44%), Gaps = 19/337 (5%) Query: 5 DEQQEQTIAEDLVVTKYKMGGDIANRVLRSLVEAS-SSGVSVLSLCEKGDAMIMEETGKI 63 +E++ A + + ++ + A+R +R V + G++++ +CEK +E+ + Sbjct: 153 EEKKALDQASEEIWNDFREAAE-AHRQVRKYVMSWIKPGMTMIEICEK-----LEDCSRK 206 Query: 64 FKKEKEMKKGIAFPTSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAH 123 KE + G+AFPT S+NNC H++P D +L+ D+ KID G H+ G I + A Sbjct: 207 LIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTT-VLQYDDICKIDFGTHISGRIIDCAF 265 Query: 124 TFVVDVAQGTQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKV--AHSFNCTP 181 T + T + K D CA +RL G +V E++ ++ P Sbjct: 266 TVTFNPKYDTLLKAVK-DATNTGIKCAGIDVRLCDVGEAIQEVMESYEVEIDGKTYQVKP 324 Query: 182 IEGMLSHQLKQHVIDGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDAG 241 I + H + Q+ I KT+ K E E EVYA++ S+G+G D Sbjct: 325 IRNLNGHSIGQYRIHAGKTV------PIIKGGEATRMEEGEVYAIETFGSTGKGVVHDDM 378 Query: 242 QRTTIYKRDPSKQYGLKMKTSRAFFSEVERRFDAMPFTLRAFE--DEKKARMGVVECAKH 299 + + K +++ ++ + + F + F R + E K M + Sbjct: 379 ECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWLDRLGESKYLMALKNLCDL 438 Query: 300 ELLQPFNVLYEKEGEFVAQFKFTVLLMPNGPMRITSG 336 ++ P+ L + +G + AQF+ T+LL P ++ G Sbjct: 439 GIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRG 475 >1XGN-A nrPDB Length = 295 Score = 288 bits (736), Expect = 3e-78, Method: Composition-based stats. Identities = 77/320 (24%), Positives = 150/320 (46%), Gaps = 33/320 (10%) Query: 19 TKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFPT 78 K G+IA +V ++ + G+ +L L E + MIME GK AFP Sbjct: 4 EKLMKAGEIAKKVREKAIKLARPGMLLLELAESIEKMIMELGGKP-----------AFPV 52 Query: 79 SISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGTQVTGR 138 ++S+N H++P K D +LKEGD +KID+GVH+DGFIA+ A T V Sbjct: 53 NLSINEIAAHYTPYKGDTT-VLKEGDYLKIDVGVHIDGFIADTAVTVRVG--------ME 103 Query: 139 KADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGMLSHQLKQHVIDGE 198 + ++++AA AA+ + + G + ++ +A PI + H+++++ + Sbjct: 104 EDELMEAAKEALNAAISVARAGVEIKELGKAIENEIRKRGFKPIVNLSGHKIERYKLHAG 163 Query: 199 KTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDAGQRTT-IYKRDPSKQYGL 257 +I + H+ + +V+A++ + G G+ + +Y RD + Sbjct: 164 ISI-----PNIYRPHDNYVLKEGDVFAIEPFATIGAGQVIEVPPTLIYMYVRD----VPV 214 Query: 258 KMKTSRAFFSEVERRFDAMPFTLRAFED---EKKARMGVVECAKHELLQPFNVLYEKEGE 314 ++ +R ++++R + +PF R ++ E + ++ + K + + VL E Sbjct: 215 RVAQARFLLAKIKREYGTLPFAYRWLQNDMPEGQLKLALKTLEKAGAIYGYPVLKEIRNG 274 Query: 315 FVAQFKFTVLLMPNGPMRIT 334 VAQF+ T+++ + + T Sbjct: 275 IVAQFEHTIIVEKDSVIVTT 294 >3FMR-A nrPDB Length = 358 Score = 283 bits (724), Expect = 8e-77, Method: Composition-based stats. Identities = 72/311 (23%), Positives = 125/311 (40%), Gaps = 36/311 (11%) Query: 40 SSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFPTSISVNNCVCHFSPLKSDQDYI 99 G+++L + I + T + K E+ GI FP +S+N+C H++ +QD + Sbjct: 67 RPGITLLEIVRS----IEDSTRTLLKGER--NNGIGFPAGMSMNSCAAHYTVNPGEQDIV 120 Query: 100 LKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGTQVTGRKADVIKAAHLCAEAALRLVKP 159 LKE D++KID G H DG I + A T + + + + +R+ Sbjct: 121 LKEDDVLKIDFGTHSDGRIMDSAFTVAFKENLEPLLVAAR-EGTETGIKSLGVDVRVCDI 179 Query: 160 GNQNTQVTEAWNKV--AHSFNCTPIEGMLSHQLKQHVIDGEKTIIQNPTDQQKKDHEKAE 217 G +V ++ + PI + H + Q I G +I + + Sbjct: 180 GRDINEVISSYEVEIGGRMWPIRPISDLHGHSISQFRIHGGISI------PAVNNRDTTR 233 Query: 218 FEVHEVYAVDVLVSSGEGKAKDAGQRTTIYKRDPSKQYGLKMKTSRAFFSE--------V 269 + YAV+ ++G+G D R P + L SR F++ V Sbjct: 234 IKGDSFYAVETFATTGKGSIDD---------RPPCSHFVLNTYKSRKLFNKDLIKVYEFV 284 Query: 270 ERRFDAMPFTLRAFEDEKKARMGVVECAK----HELLQPFNVLYEKEGEFVAQFKFTVLL 325 + +PF+ R + + G ++ LL P+ L + +G VAQF+ TV L Sbjct: 285 KDSLGTLPFSPRHLDYYGLVKGGSLKSVNLLTMMGLLTPYPPLNDIDGCKVAQFEHTVYL 344 Query: 326 MPNGPMRITSG 336 +G +T G Sbjct: 345 SEHGKEVLTRG 355 >5APN-x nrPDB Length = 616 Score = 227 bits (577), Expect = 1e-59, Method: Composition-based stats. Identities = 82/393 (20%), Positives = 151/393 (38%), Gaps = 112/393 (28%) Query: 1 MSGEDEQ---QEQTIAEDLVVTKYKMGGDIANRVLRSL---VEASSSG------VSVLSL 48 +S ED Q +++ I ++ V+ KY+ G IA L+ + + S ++V L Sbjct: 28 ISHEDTQILLKDKNILQESVLNKYRTAGQIAQTALKYVTSLINDSYHSKTTQRQLTVPEL 87 Query: 49 CEKGDAMIMEETGKIFKKEKEMKKGIAFPTSISVNNCVCHFSPLKSDQDYIL-------- 100 C D+ I+ + +K K ++GIA PT+I ++ + P D +L Sbjct: 88 CLLTDSFILTRLEQYYKN-KVNERGIAIPTTIDIDQISGGWCPEIDDTQNLLNWNKGKDS 146 Query: 101 ----------KEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGTQVTGRK----------- 139 + GDLVKI LGVH+DG+ + V+HT V+ T+ + Sbjct: 147 TFASSVTGTLRPGDLVKITLGVHIDGYTSEVSHTMVIYPVDETKPILQPTGPLLGGKADA 206 Query: 140 -------ADVIKAAHLC------AEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGML 186 + + A C A+L G + + +A S+NC + G Sbjct: 207 VAAAHIAMETVVALLACALTPEKLPASLGGTSSGITGQLIRTIVDTIARSYNCGVVPGSR 266 Query: 187 SHQLKQHVIDGEKTIIQNPTDQ---QKKDHEKAEF------------------------- 218 ++++ + + I+ + + H++A+ Sbjct: 267 VRRIRRFLAGQNEGIVAEREYKGVVWTESHQEADLLSNTDAKDLTVVDRGQSTPFTNVSA 326 Query: 219 --------EVHEVYAVDVLVSSGE-----------------GKAKDAGQ---RTTIYKRD 250 + EVY +D+ ++S E GK+ AG+ R Y RD Sbjct: 327 IPSDDFVVQSGEVYLIDLKMASLEHCTKKGLVTLETVDSYTGKSHKAGELIARPGAYVRD 386 Query: 251 PSKQYGLKMKTSRAFFSEVERRFDAMPFTLRAF 283 ++ + LK+KTSR ++++++ PF L Sbjct: 387 FAQTHILKLKTSRQLLTKIDKQ-GVYPFKLSHL 418 >4FO7-A nrPDB Length = 280 Score = 173 bits (438), Expect = 1e-43, Method: Composition-based stats. Identities = 50/235 (21%), Positives = 94/235 (40%), Gaps = 21/235 (8%) Query: 18 VTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFP 77 + K ++ G +A VL + E GV+ L I+ E K K FP Sbjct: 11 IEKMRIAGRLAAEVLEMIGEHIKPGVTTEELDRICHDYIVNEQ-KAIPAPLNYK---GFP 66 Query: 78 TSI--SVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGTQV 135 SI S+N+ VCH P + LKEGD++ +D+ V DG+ + + F+V + + Sbjct: 67 KSICTSINHVVCHGIPN----EKPLKEGDILNVDITVIKDGYHGDTSKMFLV--GKTPEW 120 Query: 136 TGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGMLSHQLKQHVI 195 R + + C + +V+PG + E K A + + H + + V Sbjct: 121 ADRLCQITQ---ECMYKGISVVRPGAHLGDIGEIIQKHAEKNGFSVVREYCGHGIGK-VF 176 Query: 196 DGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDAGQRTTIYKRD 250 E ++ + E + ++ ++ +++ G + + G T +D Sbjct: 177 HEEPQVLHYG-----RAGTGIELKEGMIFTIEPMINQGRPETRLLGDGWTAITKD 226 >3MR1-A nrPDB Length = 252 Score = 159 bits (401), Expect = 2e-39, Method: Composition-based stats. Identities = 44/216 (20%), Positives = 84/216 (38%), Gaps = 22/216 (10%) Query: 20 KYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFPTS 79 K + G +A L + + V+ SL + I K FP S Sbjct: 16 KMRAAGKLAAETLDFITDHVKPNVTTNSLNDLCHNFITS--HNAIPAPLNYK---GFPKS 70 Query: 80 I--SVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGTQVTG 137 I S+N+ VCH P D LK GD+V ID+ V +DG+ + + + V V Sbjct: 71 ICTSINHVVCHGIPN----DKPLKNGDIVNIDVTVILDGWYGDTSRMYYVG-----DVAI 121 Query: 138 RKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGMLSHQLKQHVIDG 197 + +I+ + + +V+PG + + A A N + + H + + V Sbjct: 122 KPKRLIQVTYDAMMKGIEVVRPGAKLGDIGYAIQSYAEKHNYSVVRDYTGHGIGR-VFHD 180 Query: 198 EKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSG 233 + +I+ ++ + + V+ ++++G Sbjct: 181 KPSIL-----NYGRNGTGLTLKEGMFFTVEPMINAG 211 >4A6V-A nrPDB Length = 265 Score = 158 bits (399), Expect = 4e-39, Method: Composition-based stats. Identities = 50/236 (21%), Positives = 92/236 (38%), Gaps = 22/236 (9%) Query: 18 VTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFP 77 + K ++ G +A VL + GVS L + I+ E + +P Sbjct: 11 IEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAV----SACLGYHGYP 66 Query: 78 T--SISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGTQV 135 IS+N VCH P D +LK+GD+V ID+ V DGF + + F+V + Sbjct: 67 KSVCISINEVVCHGIP---DDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVG---KPTI 120 Query: 136 TGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGMLSHQLKQHVI 195 G + + + ALR+VKPG ++ A K + + + H + + Sbjct: 121 MGER--LCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGR--- 175 Query: 196 DGEKTIIQNPTDQQKKDHE-KAEFEVHEVYAVDVLVSSGEGKAKDAGQRTTIYKRD 250 + P E + + ++ +V++G+ + + T+ +D Sbjct: 176 ----GFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKD 227 >4FUK-A nrPDB Length = 337 Score = 149 bits (377), Expect = 2e-36, Method: Composition-based stats. Identities = 46/250 (18%), Positives = 95/250 (38%), Gaps = 28/250 (11%) Query: 3 GEDEQQEQTIAEDLVVTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGK 62 +D ++ I + K ++ VL A+ G++ L +E Sbjct: 60 HDDSKKTAEI------QRIKTVCQLSREVLDIATAAAKPGITTDELDRIVHEATVER--N 111 Query: 63 IFKKEKEMKKGIAFPTSI--SVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIAN 120 ++ FP S+ SVN +CH P + L+EGD++ ID+ +++GF + Sbjct: 112 MYPSPLNY---YGFPKSVCTSVNEVICHGIPDSRE----LEEGDILNIDVSSYLNGFHGD 164 Query: 121 VAHTFVVDVAQGTQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCT 180 + T + + ++ AA+ C A + +VKP QV +A A + C+ Sbjct: 165 LNETVFIG-----RPDDDSVRLVHAAYECLCAGIGVVKPEALYKQVGDAIEACASQYQCS 219 Query: 181 PIEGMLSHQLKQHVIDGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDA 240 + H + H+ T+ ++ V+ ++ +++ G + Sbjct: 220 VVRTYTGHGVG-HLFHTSPTVCHYANNKSLG-----MMRPGHVFTIEPMINLGTWQDVTW 273 Query: 241 GQRTTIYKRD 250 + T +D Sbjct: 274 PDKWTSTTKD 283 >1O0X-A nrPDB Length = 262 Score = 143 bits (360), Expect = 1e-34, Method: Composition-based stats. Identities = 47/242 (19%), Positives = 90/242 (37%), Gaps = 23/242 (9%) Query: 18 VTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKK--GIA 75 + K K G LR + + G + + ++ E K + + K G Sbjct: 22 IEKMKKAGKAVAVALREVRKVIVPGKTAWDV-----ETLVLEIFKKLRVKPAFKGYGGYK 76 Query: 76 FPTSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGTQV 135 + T +SVN V H PLK + + KEGD+V +D+G G + A T++V + Sbjct: 77 YATCVSVNEEVVHGLPLK---EKVFKEGDIVSVDVGAVYQGLYGDAAVTYIVG-----ET 128 Query: 136 TGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGMLSHQLKQHVI 195 R ++++ E A++++KPG + V+ + S I + H + + + Sbjct: 129 DERGKELVRVTREVLEKAIKMIKPGIRLGDVSHCIQETVESVGFNVIRDYVGHGVGR-EL 187 Query: 196 DGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGK--AKDAGQRTTIYKRDPSK 253 + I A++ +VS G+ + K+ G Sbjct: 188 HEDPQI-----PNYGTPGTGVVLRKGMTLAIEPMVSEGDWRVVVKEDGWTAVTVDGSRCA 242 Query: 254 QY 255 + Sbjct: 243 HF 244 >3ROR-A nrPDB Length = 291 Score = 142 bits (357), Expect = 3e-34, Method: Composition-based stats. Identities = 36/220 (16%), Positives = 74/220 (33%), Gaps = 22/220 (10%) Query: 17 VVTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAF 76 V+ K ++ G IA L +A + GV+ L +++ F Sbjct: 52 VIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNG-----AYPSTLGYKGF 106 Query: 77 PTSIS--VNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGTQ 134 P S S +N +CH P + ++ +GD+V ID+ ++ G + TF Sbjct: 107 PKSCSTSLNEVICHGIPDST----VITDGDIVNIDVTAYIGGVHGDTNATFPAG-----D 157 Query: 135 VTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGMLSHQLKQHV 194 V ++ A+ VKPG + + A+ F + H + Sbjct: 158 VADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGT-T 216 Query: 195 IDGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGE 234 ++ + + + ++ +++ G Sbjct: 217 FHNGLVVLHYDQPAV-----ETIMQPGMTFTIEPMINLGA 251 >4IU6-A nrPDB Length = 384 Score = 142 bits (357), Expect = 3e-34, Method: Composition-based stats. Identities = 40/235 (17%), Positives = 85/235 (36%), Gaps = 22/235 (9%) Query: 18 VTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFP 77 + ++ +A VL GV+ + + + FP Sbjct: 136 IEGMRLVCRLAREVLDVAAGMIKPGVTTEEIDHAVHLACI--ARNCYPSPLNY---YNFP 190 Query: 78 TSI--SVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGTQV 135 S SVN +CH P + L+EGD+V +D+ ++ +G+ ++ TF V +V Sbjct: 191 KSCCTSVNEVICHGIPDRR----PLQEGDIVNVDITLYRNGYHGDLNETFFVG-----EV 241 Query: 136 TGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGMLSHQLKQHVI 195 +++ + C A+ VKPG + ++ K A + + + H + + + Sbjct: 242 DDGARKLVQTTYECLMQAIDAVKPGVRYRELGNIIQKHAQANGFSVVRSYCGHGIHK-LF 300 Query: 196 DGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDAGQRTTIYKRD 250 + K+ + V+ ++ ++ G + + T RD Sbjct: 301 HTAPNV-----PHYAKNKAVGVMKSGHVFTIEPMICEGGWQDETWPDGWTAVTRD 350 Score = 33.6 bits (75), Expect = 0.15, Method: Composition-based stats. Identities = 31/239 (12%), Positives = 77/239 (32%), Gaps = 52/239 (21%) Query: 142 VIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGMLSHQLKQHVIDGEKTI 201 V + A + A ++KPG ++ A + + NC P + + + + Sbjct: 142 VCRLAREVLDVAAGMIKPGVTTEEIDHAVHLACIARNCYPSP-LNYYNFPKSCCTSVNEV 200 Query: 202 IQNPTDQQKKDHEKAEFEVHEVYAVDVLV-----------SSGEGKAKDAGQRTTIYKRD 250 I + ++ + ++ VD+ + + G+ D ++ + Sbjct: 201 ICHGIP------DRRPLQEGDIVNVDITLYRNGYHGDLNETFFVGEVDDGARKLVQTTYE 254 Query: 251 PSKQYGLKMK---TSRAFFSEVERRFDAMPFTL-RAFEDEKKARM--------------G 292 Q +K R + +++ A F++ R++ ++ Sbjct: 255 CLMQAIDAVKPGVRYRELGNIIQKHAQANGFSVVRSYCGHGIHKLFHTAPNVPHYAKNKA 314 Query: 293 VVECAKHELLQPFNVLYE----------------KEGEFVAQFKFTVLLMPNGPMRITS 335 V + ++ E ++G+ AQF+ T+L+ G +T Sbjct: 315 VGVMKSGHVFTIEPMICEGGWQDETWPDGWTAVTRDGKRSAQFEHTLLVTDTGCEILTR 373 >2B3K-A nrPDB Length = 329 Score = 142 bits (357), Expect = 3e-34, Method: Composition-based stats. Identities = 40/235 (17%), Positives = 85/235 (36%), Gaps = 22/235 (9%) Query: 18 VTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFP 77 + ++ +A VL GV+ + + + FP Sbjct: 81 IEGMRLVCRLAREVLDVAAGMIKPGVTTEEIDHAVHLACI--ARNCYPSPLNY---YNFP 135 Query: 78 TSI--SVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGTQV 135 S SVN +CH P + L+EGD+V +D+ ++ +G+ ++ TF V +V Sbjct: 136 KSCCTSVNEVICHGIPDRR----PLQEGDIVNVDITLYRNGYHGDLNETFFVG-----EV 186 Query: 136 TGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGMLSHQLKQHVI 195 +++ + C A+ VKPG + ++ K A + + + H + + + Sbjct: 187 DDGARKLVQTTYECLMQAIDAVKPGVRYRELGNIIQKHAQANGFSVVRSYCGHGIHK-LF 245 Query: 196 DGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDAGQRTTIYKRD 250 + K+ + V+ ++ ++ G + + T RD Sbjct: 246 HTAPNV-----PHYAKNKAVGVMKSGHVFTIEPMICEGGWQDETWPDGWTAVTRD 295 Score = 33.6 bits (75), Expect = 0.15, Method: Composition-based stats. Identities = 31/239 (12%), Positives = 77/239 (32%), Gaps = 52/239 (21%) Query: 142 VIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGMLSHQLKQHVIDGEKTI 201 V + A + A ++KPG ++ A + + NC P + + + + Sbjct: 87 VCRLAREVLDVAAGMIKPGVTTEEIDHAVHLACIARNCYPSP-LNYYNFPKSCCTSVNEV 145 Query: 202 IQNPTDQQKKDHEKAEFEVHEVYAVDVLV-----------SSGEGKAKDAGQRTTIYKRD 250 I + ++ + ++ VD+ + + G+ D ++ + Sbjct: 146 ICHGIP------DRRPLQEGDIVNVDITLYRNGYHGDLNETFFVGEVDDGARKLVQTTYE 199 Query: 251 PSKQYGLKMK---TSRAFFSEVERRFDAMPFTL-RAFEDEKKARM--------------G 292 Q +K R + +++ A F++ R++ ++ Sbjct: 200 CLMQAIDAVKPGVRYRELGNIIQKHAQANGFSVVRSYCGHGIHKLFHTAPNVPHYAKNKA 259 Query: 293 VVECAKHELLQPFNVLYE----------------KEGEFVAQFKFTVLLMPNGPMRITS 335 V + ++ E ++G+ AQF+ T+L+ G +T Sbjct: 260 VGVMKSGHVFTIEPMICEGGWQDETWPDGWTAVTRDGKRSAQFEHTLLVTDTGCEILTR 318 >3TAV-A nrPDB Length = 286 Score = 140 bits (352), Expect = 1e-33, Method: Composition-based stats. Identities = 56/230 (24%), Positives = 98/230 (42%), Gaps = 29/230 (12%) Query: 18 VTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFP 77 + G I L ++ +A+ +GVS L L + +++I E G + FP Sbjct: 40 LDAMAAAGSIVGAALVAVRDAAKAGVSTLELDQVAESVI-REAGAV----PSFLGYHGFP 94 Query: 78 TSI--SVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGTQV 135 SI SVN+ V H P +L +GDLV ID G +DG+ + A TF V GT + Sbjct: 95 ASICSSVNDQVVHGIPSA---TAVLADGDLVSIDCGAILDGWHGDSAWTFAV----GTVI 147 Query: 136 TGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHS------FNCTPIEGMLSHQ 189 +A + +A L EA + + PGN+ T V+ A + ++G H Sbjct: 148 PSDEA-LSEATRLSMEAGIAAMIPGNRLTDVSHAIELGTRAAEKQFDRAFGIVDGYGGHG 206 Query: 190 LKQHVIDGEKTIIQNP-TDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAK 238 + + ++ +P + + V V A++ +++ G + + Sbjct: 207 IGR-------SMHLDPFLPNEGAPGKGPLLAVGSVLAIEPMLTLGTTQTR 249 >6MRF-A nrPDB Length = 270 Score = 138 bits (346), Expect = 5e-33, Method: Composition-based stats. Identities = 49/238 (20%), Positives = 88/238 (36%), Gaps = 19/238 (7%) Query: 18 VTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFP 77 + K ++ G +A VL + +GVS L L I I P Sbjct: 16 IEKMRIAGRLAAEVLDMIKPHIKAGVSTLELDTICRNHIENVQHAI-PACVGYGGAPGRP 74 Query: 78 T-----SISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQG 132 SVN+ VCH P ++ ILK GD++ ID+ V DG+ + ++V G Sbjct: 75 AFQHSICTSVNHVVCHGIPS---ENKILKNGDILNIDVTVIKDGYHGDTNMMYIV----G 127 Query: 133 TQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGMLSHQLKQ 192 + + + K A + V+ G+ + A K S + + H + Sbjct: 128 GETSILANRLCKVAQEAMYRGMATVRDGSYLGDIGHAIQKYVESERFSVVREYCGHGIGT 187 Query: 193 HVIDGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDAGQRTTIYKRD 250 V E ++ + E + ++ +V++G + K G + T+ +D Sbjct: 188 -VFHDEPQVLHYG-----QAGTGMRLEAGMTFTIEPMVNAGVWQTKLLGDKWTVVTKD 239 >1QXW-A nrPDB Length = 252 Score = 138 bits (346), Expect = 6e-33, Method: Composition-based stats. Identities = 55/260 (21%), Positives = 99/260 (38%), Gaps = 21/260 (8%) Query: 18 VTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFP 77 + K G I +V ++ A+ G++ L + E E G Sbjct: 9 LQALKEIGYICAKVRNTMQAATKPGITTKELDNIAKELFEEYGAISAPIHDENFPGQ--- 65 Query: 78 TSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGTQVTG 137 T ISVN V H P K +++EGDLV ID+ +G+ A+ +FVV + Sbjct: 66 TCISVNEEVAHGIPSKR----VIREGDLVNIDVSALKNGYYADTGISFVVGESDDP---- 117 Query: 138 RKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGMLSHQLKQHVIDG 197 K V A + E A+ VKPG + + + +A + A + I+ + H + + + Sbjct: 118 MKQKVCDVATMAFENAIAKVKPGTKLSNIGKAVHNTARQNDLKVIKNLTGHGVGLSLHEA 177 Query: 198 EKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSG-----EGKAKDAGQRTTIYKRDPS 252 ++ +K V A++ +SS EGK + A + + Sbjct: 178 PAHVL-----NYFDPKDKTLLTEGMVLAIEPFISSNASFVTEGKNEWAFETSDKSFVAQI 232 Query: 253 KQYGLKMKTSRAFFSEVERR 272 + + K +++E Sbjct: 233 EHTVIVTKDGPILTTKIEEE 252 Score = 29.4 bits (64), Expect = 2.7, Method: Composition-based stats. Identities = 9/24 (37%), Positives = 15/24 (62%) Query: 312 EGEFVAQFKFTVLLMPNGPMRITS 335 + FVAQ + TV++ +GP+ T Sbjct: 225 DKSFVAQIEHTVIVTKDGPILTTK 248 >3TB5-A nrPDB Length = 264 Score = 137 bits (344), Expect = 1e-32, Method: Composition-based stats. Identities = 43/234 (18%), Positives = 86/234 (36%), Gaps = 20/234 (8%) Query: 18 VTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFP 77 + G++ V R L G++ + I G + E G + Sbjct: 10 IEMMDESGELLADVHRHLRTFIKPGITSWDIEVFVRDFIESHGGVAAQIGYE---GYKYA 66 Query: 78 TSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGTQVTG 137 T S+N+ +CH P K +LK+GDL+K+D+ V + G I++ ++VV + T Sbjct: 67 TCCSINDEICHGFPRK----KVLKDGDLIKVDMCVDLKGAISDSCWSYVVG-----ESTP 117 Query: 138 RKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGMLSHQLKQHVIDG 197 +++ + + GN+ + A + + H + Sbjct: 118 EIDRLMEVTKKALYLGIEQAQVGNRIGDIGHAIQTYVEGEGYGVVRDFVGHGI------- 170 Query: 198 EKTIIQNPTDQQKKD-HEKAEFEVHEVYAVDVLVSSGEGKAKDAGQRTTIYKRD 250 TI ++P + + + V ++ +V++G + K T Y D Sbjct: 171 GPTIHESPMIPHYGEAGKGLRLKEGMVITIEPMVNTGTWRMKMDPNGWTAYTED 224 >3S6B-A nrPDB Length = 368 Score = 133 bits (334), Expect = 1e-31, Method: Composition-based stats. Identities = 38/229 (16%), Positives = 81/229 (35%), Gaps = 19/229 (8%) Query: 7 QQEQTIAEDLVVTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKK 66 + + + + + + + + + L S GV+ + K I++ Sbjct: 98 KSDIYVNNEEEIQRIREACILGRKTLDYAHTLVSPGVTTDEIDRKVHEFIIKN-----NA 152 Query: 67 EKEMKKGIAFPTSI--SVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHT 124 FP S SVN VCH P LK GD++ ID+ V G +++ T Sbjct: 153 YPSTLNYYKFPKSCCTSVNEIVCHGIPDYR----PLKSGDIINIDISVFYKGVHSDLNET 208 Query: 125 FVVDVAQGTQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEG 184 + V V ++++ + A++ KPG + + N + + Sbjct: 209 YFVGDIND--VPKEGKELVETCYFSLMEAIKKCKPGMFYKNIGTLIDAYVSKKNFSVVRS 266 Query: 185 MLSHQLKQHVIDGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSG 233 H + + + T+ KK+ + V+ ++ +++ G Sbjct: 267 YSGHGVGK-LFHSNPTV-----PHFKKNKAVGIMKPGHVFTIEPMINQG 309 Score = 32.1 bits (71), Expect = 0.43, Method: Composition-based stats. Identities = 9/24 (37%), Positives = 15/24 (62%) Query: 312 EGEFVAQFKFTVLLMPNGPMRITS 335 +G+ AQF+ T+L+ NG +T Sbjct: 326 DGKLSAQFEHTLLITNNGVEILTK 349 >5WZE-A nrPDB Length = 452 Score = 108 bits (270), Expect = 4e-24, Method: Composition-based stats. Identities = 51/250 (20%), Positives = 97/250 (38%), Gaps = 37/250 (14%) Query: 21 YKMGGDIANRVLRSLVEASSSG-VSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIA-FPT 78 YK ++ +V+R E S+ + + +C G + E + E E +KG A P Sbjct: 175 YKSANEV--KVMRYAAEVSARAHIRAMEVCRPG----LFEYHLEAELEYEFRKGGAKMPA 228 Query: 79 SISV-----NNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGT 133 S+ N C+ H+ + D +K+GDL+ ID G +D + +++ TF A G Sbjct: 229 YGSIVAAGRNACILHY----RENDAAIKDGDLILIDAGCEIDCYASDITRTF---PANGR 281 Query: 134 QVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGMLSHQLKQH 193 +KA + + AA + PG + EA + + + ++ Sbjct: 282 FSPEQKA-IYELVLEANMAAFDYIAPGRHWNEAHEA-----------TVRVITAGLVRLG 329 Query: 194 VIDGEK-TIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDAGQ----RTTIYK 248 +++G+ +I + + H + +V+ V GE + + G IY Sbjct: 330 LLEGDVDELIAHEAYKAFYMHRAGHWLGMDVHDVGEYRVGGEWRVLEPGMAMTVEPGIYI 389 Query: 249 RDPSKQYGLK 258 + K Sbjct: 390 APDNTTVAKK 399 >4PV4-A nrPDB Length = 445 Score = 98.0 bits (242), Expect = 6e-21, Method: Composition-based stats. Identities = 41/157 (26%), Positives = 68/157 (43%), Gaps = 21/157 (13%) Query: 21 YKMGGDIANRVLRSLVEASS-SGVSVLSLCEKGDAMIMEETGKIFKKEKEM-KKGIAFPT 78 +K +IA VLR E S+ + + C G M E + E + G +P Sbjct: 173 FKSAEEIA--VLRRAGEISALAHTRAMEKCRPG----MFEYQLEGEILHEFTRHGARYPA 226 Query: 79 SISV-----NNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGT 133 ++ N C+ H++ + + L++GDLV ID G G+ ++ TF V+ + T Sbjct: 227 YNTIVGGGENGCILHYTENECE----LRDGDLVLIDAGCEYRGYAGDITRTFPVN-GKFT 281 Query: 134 QVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAW 170 D++ AA +L L +PG +VTE Sbjct: 282 PAQRAVYDIVLAA---INKSLTLFRPGTSIREVTEEV 315 >2BWY-A nrPDB Length = 440 Score = 97.6 bits (241), Expect = 9e-21, Method: Composition-based stats. Identities = 39/154 (25%), Positives = 68/154 (44%), Gaps = 21/154 (13%) Query: 21 YKMGGDIANRVLRSLVEASSSG-VSVLSLCEKGDAMIMEETGKIFKKEKEMK-KGIAFPT 78 +K +IA VLR E ++ + C G M E + E G +P+ Sbjct: 175 FKSPEEIA--VLRRAGEITAMAHTRAMEKCRPG----MFEYHLEGEIHHEFNRHGARYPS 228 Query: 79 SISV-----NNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGT 133 ++ N C+ H++ + + +++GDLV ID G G+ ++ TF V+ + T Sbjct: 229 YNTIVGSGENGCILHYTENECE----MRDGDLVLIDAGCEYKGYAGDITRTFPVN-GKFT 283 Query: 134 QVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVT 167 Q D++ + E +LRL +PG +VT Sbjct: 284 QAQREIYDIVLES---LETSLRLYRPGTSILEVT 314 >4KM3-A nrPDB Length = 286 Score = 97.2 bits (240), Expect = 1e-20, Method: Composition-based stats. Identities = 37/260 (14%), Positives = 77/260 (29%), Gaps = 45/260 (17%) Query: 18 VTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFK-KEKEMKKGIAF 76 + GD + L + GV + + E EE + + Sbjct: 10 IEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYVRRRCKEENFLPLQIGVDGAMMDYPY 69 Query: 77 PTSISVNNCVCHFSPLKSDQDYILKEGDLVKIDL-------------------------- 110 T S+N+ V H P YILK+GDL+K+D+ Sbjct: 70 ATCCSLNDEVAHAFPR----HYILKDGDLLKVDMVLGGPIAKSDLNVSKLNFNNVEQMKK 125 Query: 111 -GVHVDGFIANVAHTFVVDVAQGTQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEA 169 G +A+ + V + +++ + GN+ + A Sbjct: 126 YTQSYSGGLADSCWAYAVG-----TPSEEVKNLMDITKEAMYKGIEQAVVGNRIGDIGAA 180 Query: 170 WNKVAHSFNCTPIEGMLSHQLKQHVIDGEKTIIQNPTDQQKK-DHEKAEFEVHEVYAVDV 228 + A S + ++ H + T+ + P V ++ Sbjct: 181 IQEYAESRGYGVVRDLVGHGV-------GPTMHEEPMVPNYGIAGRGLRLREGMVLTIEP 233 Query: 229 LVSSGEGKAKDAGQRTTIYK 248 ++++G+ + + +K Sbjct: 234 MINTGDWEIDTDMKTGWAHK 253 Score = 30.2 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 6/25 (24%), Positives = 14/25 (56%) Query: 311 KEGEFVAQFKFTVLLMPNGPMRITS 335 +G Q++ ++ +GP+ +TS Sbjct: 255 IDGGLSCQYEHQFVITKDGPVILTS 279 >5CNX-A nrPDB Length = 361 Score = 69.1 bits (167), Expect = 4e-12, Method: Composition-based stats. Identities = 35/222 (15%), Positives = 78/222 (35%), Gaps = 22/222 (9%) Query: 18 VTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFP 77 V K ++ IA+R + +G+S + + + + ++ + + + G Sbjct: 133 VEKIRLACGIADRGAEHIRRFIQAGMSEREIAAELEWFMRQQGAEKASFDTIVASGWR-- 190 Query: 78 TSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGTQVTG 137 P D I+ G+ V +D G G+ +++ T +V+ + + Sbjct: 191 ----------GALPHGKASDKIVAAGEFVTLDFGALYQGYCSDMTRTLLVNGEGVSAESH 240 Query: 138 RKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGMLSHQLKQHVIDG 197 +V + AA+ ++PG + QV +A +V H H I Sbjct: 241 LLFNVYQIVLQAQLAAISAIRPGVRCQQVDDAARRVITEAGYG---DYFGHNTG-HAIG- 295 Query: 198 EKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSS-GEGKAK 238 I+ D + + + + V+ + G+G + Sbjct: 296 ----IEVHEDPRFSPRDTTTLQPGMLLTVEPGIYLPGQGGVR 333 >3Q6D-A nrPDB Length = 356 Score = 62.9 bits (151), Expect = 2e-10, Method: Composition-based stats. Identities = 25/216 (11%), Positives = 64/216 (29%), Gaps = 20/216 (9%) Query: 7 QQEQTIAEDLVVTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKK 66 ++ + I D + K IA+ ++ GVS + + + + + ++ Sbjct: 125 EKLRLIKTDSEIKILKEAAQIADAAFEHILSFIRPGVSEIEVSNELEFFMRKQGATSSSF 184 Query: 67 EKEMKKGIAFPTSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFV 126 + + G+ P + +++ GD V +D G + G+ +++ T Sbjct: 185 DIIVASGLRSA------------LPHGVASEKVIETGDFVTLDFGAYYKGYCSDITRTIA 232 Query: 127 VDVAQGTQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEG-M 185 V + + + ++ + +K G + G Sbjct: 233 VG-----EPSDKLKEIYNIVLEAQLRGVNGIKAGLTGREADALTRDYITEKGYGEYFGHS 287 Query: 186 LSHQLKQHVIDGEKTIIQNPTDQQKKDHEKAEFEVH 221 H + I + +D + E Sbjct: 288 TGHGIG-LEIHEAPGL-AFRSDTVLEPGMAVTVEPG 321 >1PV9-A nrPDB Length = 348 Score = 59.5 bits (142), Expect = 2e-09, Method: Composition-based stats. Identities = 31/221 (14%), Positives = 73/221 (33%), Gaps = 29/221 (13%) Query: 10 QTIAEDLVVTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKKEKE 69 +T E ++ K +IA++ + + +E + G + K + ++ + + Sbjct: 125 KTKEEIEIIEK---ACEIADKAVMAAIEEITEGKREREVAAKVEYLMKMNGAEKPAFDTI 181 Query: 70 MKKGIAFPTSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDV 129 + G P D ++ GDLV IDLG + + +++ T VV Sbjct: 182 IASGHRSA------------LPHGVASDKRIERGDLVVIDLGALYNHYNSDITRTIVVGS 229 Query: 130 AQGTQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGMLSHQ 189 Q ++ + + A+ KPG ++ ++ + H Sbjct: 230 PNEKQ-----REIYEIVLEAQKRAVEAAKPGMTAKELDSIAREIIKEYGYG---DYFIHS 281 Query: 190 LKQHVIDGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLV 230 L I + +++ + V ++ + Sbjct: 282 LGH---GVGLEI---HEWPRISQYDETVLKEGMVITIEPGI 316 Score = 36.0 bits (81), Expect = 0.030, Method: Composition-based stats. Identities = 21/114 (18%), Positives = 42/114 (36%), Gaps = 11/114 (9%) Query: 2 SGEDEQQEQTIAEDLVVTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETG 61 + + +TI K + +I + VEA+ G++ L +I Sbjct: 215 NHYNSDITRTIVVGSPNEKQREIYEIVLEAQKRAVEAAKPGMTAKELDSIAREII----- 269 Query: 62 KIFKKEKEMKKGIAFPTSISVNNCVCHFSPLKSDQDY-ILKEGDLVKIDLGVHV 114 K + + + + H P S D +LKEG ++ I+ G+++ Sbjct: 270 KEYGYGDYFIHSLGHGVGLEI-----HEWPRISQYDETVLKEGMVITIEPGIYI 318 >2ZSG-A nrPDB Length = 359 Score = 59.5 bits (142), Expect = 2e-09, Method: Composition-based stats. Identities = 32/214 (14%), Positives = 72/214 (33%), Gaps = 27/214 (12%) Query: 4 EDEQQEQTIAEDLVVTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKI 63 ++ +Q + + ++ + K K +I+ R V+ +G++ + + Sbjct: 125 DEVKQMRMVKDEGEIEKIKQAIEISERAFLETVQQIRAGMTEKEIAALLE---------- 174 Query: 64 FKKEKEMKKGIAFPTSISVNNCVCHFS----PLKSDQDYILKEGDLVKIDLGVHVDGFIA 119 + KE +G+AF T V P D +++ GD++ ID G + + A Sbjct: 175 YTMRKEGAEGVAFDT------IVASGCRSALPHGKASDKVVERGDVIVIDFGATYENYCA 228 Query: 120 NVAHTFVVDVAQGTQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNC 179 ++ + + + +V E AL++ K G + + Sbjct: 229 DITRVVSIG-----EPSDEVKEVHSIVLEAQERALKIAKAGVTGKLLDSVAREFIREKGY 283 Query: 180 TPIEG-MLSHQLKQHVIDGEKTIIQNPTDQQKKD 212 G L H + + I ++ Sbjct: 284 GEFFGHSLGHGIG-LEVHEGPAISFRNDSPLPEN 316 >1WY2-A nrPDB Length = 351 Score = 59.1 bits (141), Expect = 3e-09, Method: Composition-based stats. Identities = 28/220 (12%), Positives = 70/220 (31%), Gaps = 28/220 (12%) Query: 12 IAEDLVVTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKKEKEMK 71 I + + + +IA++ + + +E + G + K + ++ + + + Sbjct: 127 IKSEKEIKIIEKACEIADKAVMAAIEEITEGKKEREVAAKVEYLMKMNGAEKPAFDTIIA 186 Query: 72 KGIAFPTSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQ 131 G P D ++ GDLV IDLG + +++ T VV Sbjct: 187 SGYRSA------------LPHGVASDKRIERGDLVVIDLGALYQHYNSDITRTIVVGSPN 234 Query: 132 GTQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEG-MLSHQL 190 Q ++ + + A+ KPG ++ + + L H + Sbjct: 235 EKQ-----KEIYEIVLEAQKKAVESAKPGITAKELDSIARNIIAEYGYGEYFNHSLGHGV 289 Query: 191 KQHVIDGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLV 230 ++ + +++ V ++ + Sbjct: 290 G----------LEVHEWPRVSQYDETVLREGMVITIEPGI 319 Score = 37.5 bits (85), Expect = 0.009, Method: Composition-based stats. Identities = 24/143 (16%), Positives = 52/143 (36%), Gaps = 12/143 (8%) Query: 3 GEDEQQEQTIAEDLVVTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGK 62 + +TI K K +I + VE++ G++ L +I E Sbjct: 219 HYNSDITRTIVVGSPNEKQKEIYEIVLEAQKKAVESAKPGITAKELDSIARNIIAEYGYG 278 Query: 63 IFKKEKEMKKGIAFPTSISVNNCVCHFSPLKSDQDY-ILKEGDLVKIDLGVHVDGFIA-N 120 + + + V H P S D +L+EG ++ I+ G+++ Sbjct: 279 EY-----FNHSLGHGVGLEV-----HEWPRVSQYDETVLREGMVITIEPGIYIPKIGGVR 328 Query: 121 VAHTFVVDVAQGTQVTGRKADVI 143 + T ++ ++T + ++I Sbjct: 329 IEDTILITKNGSKRLTKTERELI 351 >5MC5-A nrPDB Length = 478 Score = 54.4 bits (129), Expect = 8e-08, Method: Composition-based stats. Identities = 28/164 (17%), Positives = 63/164 (38%), Gaps = 21/164 (12%) Query: 15 DLVVTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGI 74 D+ + + I++ R +++A G+ E +F+ + G+ Sbjct: 184 DMELEVLRYTNKISSEAHREVMKAVKVGMK------------EYELESLFEHYCYSRGGM 231 Query: 75 AFPTSISV-----NNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDV 129 + + N+ V H+ + D ++ GD+ D+G F +++ +F Sbjct: 232 RHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMCLFDMGGEYYCFASDITCSF---P 288 Query: 130 AQGTQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKV 173 A G +KA V +A + A + +KPG + +++ Sbjct: 289 ANGKFTADQKA-VYEAVLRSSRAVMGAMKPGVWWPDMHRLADRI 331 >3IG4-A nrPDB Length = 427 Score = 53.3 bits (126), Expect = 2e-07, Method: Composition-based stats. Identities = 36/185 (19%), Positives = 66/185 (35%), Gaps = 23/185 (12%) Query: 54 AMIMEETGKIFKKEKEMKKGIAFPTSISV-----NNCVCHFSPLKSDQDYILKEGDLVKI 108 M+ E F + GI ++ N V H+ D D ++ GDLV + Sbjct: 201 DMMEYELEAQFDFTLK-SSGIKHHAFNTILASGKNATVLHY----EDNDAQIQNGDLVLL 255 Query: 109 DLGVHVDGFIANVAHTFVVDVAQGTQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTE 168 DLG D + A++++TF A GT R+ + + ++KPG + Sbjct: 256 DLGAQKDYYNADISYTF---PANGTFS-SRQKQIYNIVLNALKETTEIIKPGLKFA---- 307 Query: 169 AWNKVAHSF---NCTPIEGML-SHQLKQHVIDGEKTIIQNPTDQQKKDHEKAEFEVHEVY 224 A N+ A C + + +L ++ G + ++ E V Sbjct: 308 ALNEHAKKVLAEGCKAVGLIQEDEELSKYYYHG-VSHFLGLDTHDVGTYKDRVLEEGMVI 366 Query: 225 AVDVL 229 ++ Sbjct: 367 TIEPG 371 >4ZNG-C nrPDB Length = 362 Score = 52.9 bits (125), Expect = 2e-07, Method: Composition-based stats. Identities = 33/218 (15%), Positives = 71/218 (32%), Gaps = 34/218 (15%) Query: 18 VTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFP 77 + K K+ GD A++ + + + E+ + K E EMK+ + P Sbjct: 140 IEKMKVAGDFADKCFE------------IGFATAAERNGVTESDIVAKIEYEMKR-MGVP 186 Query: 78 TSISVNNCVCHFS----PLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGT 133 +S + V + P + ++ ++E L+ DLGV G+ ++ T + Sbjct: 187 Q-MSFDTLVLSGARAANPHGAPENVEIQENKLLLFDLGVMSGGYASDATRTIAIG----- 240 Query: 134 QVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGML-SHQLKQ 192 Q A++ K +AA+ +KPG +V + H + Sbjct: 241 QPNDFDAEIHKIVKEAQQAAMDFIKPGVTAHEVDAVARDLITKAGYGEYFNHRLGHGIG- 299 Query: 193 HVIDGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLV 230 + + ++ + + Sbjct: 300 ---------MDVHEYPSIVAGNDLVIQEGMCFSNEPGI 328 >5X49-A nrPDB Length = 456 Score = 51.0 bits (120), Expect = 9e-07, Method: Composition-based stats. Identities = 32/251 (12%), Positives = 79/251 (31%), Gaps = 39/251 (15%) Query: 7 QQEQTIAEDLVVTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKK 66 Q+ + I + + ++ G + ++ + S + V L K + I Sbjct: 190 QRLRLIKSPAEIERMQIAGKLTSQAFIETMFTSKAPVEEAFLYAKFEFECRARGADILAY 249 Query: 67 EKEMKKGIAFPTSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFV 126 + G T H+ + ++K+G++V +D G +++++ T+ Sbjct: 250 PPVVAGGNRSNT--------LHYV----KNNQLIKDGEMVLLDGGCESSCYVSDITRTWP 297 Query: 127 VDVAQGTQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTE--------------AWNK 172 V+ + T +A++ +A L L PG + Sbjct: 298 VNG----RFTAPQAELYEAVLEIQRDCLALCFPGTSLENIYSMMLTLIGQKLKDLGIMKN 353 Query: 173 VAHSFNCTPIEGMLSHQLKQHVIDGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSS 232 + + H + ++ + P + + V ++ + Sbjct: 354 IKENNAFKAARKYCPHHVGHYL---GMDVHDTPDMPRSLP-----LQPGMVITIEPGIYI 405 Query: 233 GEGKAKDAGQR 243 E KDA ++ Sbjct: 406 PEDD-KDAPEK 415 >3RVA-A nrPDB Length = 451 Score = 44.4 bits (103), Expect = 7e-05, Method: Composition-based stats. Identities = 21/138 (15%), Positives = 50/138 (36%), Gaps = 8/138 (5%) Query: 32 LRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFPTSISVNN--CVCHF 89 +R + + +G + + ++ + + + +++N + H+ Sbjct: 168 MREANKLAVAGHKAAEQAFREGKSEFDINLAYAAASRQGDNDVPYTSIVALNEHASILHY 227 Query: 90 SPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGTQVTGRKADVIKAAHLC 149 + D KE ID G + G+ A++ T+ +G + D+I+A Sbjct: 228 M--QCDTVAP-KESRSFLIDAGANYHGYAADITRTY---AQEGVHNSAMFRDLIQAVDKV 281 Query: 150 AEAALRLVKPGNQNTQVT 167 + +KPG T + Sbjct: 282 TLTLVDSLKPGVAYTDIH 299 >3L7G-A nrPDB Length = 517 Score = 39.8 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 31/230 (13%), Positives = 74/230 (32%), Gaps = 31/230 (13%) Query: 21 YKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFPTSI 80 + IA + ++ +A G S + + A ++ ++ Sbjct: 168 MREANKIAVQGHKAARDAFFQGKSEFEIQQ---AYLLATQHSENDNPYGNI------VAL 218 Query: 81 SVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGTQVTGRKA 140 + N + H++ + ID G + +G+ A++ T+ G A Sbjct: 219 NENCAILHYTHFDRVAPATHRS---FLIDAGANFNGYAADITRTY------DFTGEGEFA 269 Query: 141 DVIKAAHLCAEAALRLVKPGNQNTQVT-EAWNKVAHSFNCTPIEGMLSHQLKQHVIDGEK 199 +++ A + + PG ++ + +VA + + I + + ++ K Sbjct: 270 ELVATMKQHQIALMNQLAPGKLYGELHLDCHQRVAQTLSDFNIVDLSADEI------VAK 323 Query: 200 TIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDAGQRTTIYKR 249 I H +VH+V ++ +G A + R Sbjct: 324 GITSTFFPHGLGHHIG--LQVHDVGG---FMADEQG-AHQEPPEGHPFLR 367 >4ZWP-A nrPDB Length = 440 Score = 37.1 bits (84), Expect = 0.012, Method: Composition-based stats. Identities = 31/230 (13%), Positives = 74/230 (32%), Gaps = 31/230 (13%) Query: 21 YKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFPTSI 80 + IA + ++ +A G S + ++ + + E ++ Sbjct: 168 MREANKIAVQGHKAARDAFFQGKSEFEI---------QQAYLLATQHSENDTPFGNIVAL 218 Query: 81 SVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGTQVTGRKA 140 + N + H++ + ID G + +G+ A++ T+ G A Sbjct: 219 NENCAILHYTHFDRVAPATHRS---FLIDAGANFNGYAADITRTY------DFTGEGEFA 269 Query: 141 DVIKAAHLCAEAALRLVKPGNQNTQVT-EAWNKVAHSFNCTPIEGMLSHQLKQHVIDGEK 199 +++ A + PG ++ + +VA + + I + + ++ K Sbjct: 270 ELVATMKQHQIALCNQLAPGKLYGELHLDCHQRVAQTLSDFNIVNLSADEI------VAK 323 Query: 200 TIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDAGQRTTIYKR 249 I H +VH+V ++ +G A + R Sbjct: 324 GITSTFFPHGLGHHIG--LQVHDVGG---FMADEQG-AHQEPPEGHPFLR 367 >4QR8-A nrPDB Length = 443 Score = 34.4 bits (77), Expect = 0.082, Method: Composition-based stats. Identities = 22/141 (15%), Positives = 45/141 (31%), Gaps = 17/141 (12%) Query: 21 YKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFPTSI 80 + +A R+ EA SG+S + A + + + Sbjct: 170 MREAQKMAVNGHRAAEEAFRSGMSEFDI---NIAYLTATGHRDTDVPYSNI--------V 218 Query: 81 SVNN--CVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQG-TQVTG 137 ++N V H++ L ++ +D G +G+ A++ T+ Q+ Sbjct: 219 ALNEHAAVLHYTKLDHQAPEEMRS---FLLDAGAEYNGYAADLTRTWSAKSDNDYAQLVK 275 Query: 138 RKADVIKAAHLCAEAALRLVK 158 D A +A + V Sbjct: 276 DVNDEQLALIATMKAGVSYVD 296 >1K3I-A nrPDB Length = 656 Score = 31.0 bits (68), Expect = 0.94, Method: Composition-based stats. Identities = 26/145 (17%), Positives = 54/145 (37%), Gaps = 19/145 (13%) Query: 216 AEFEVHEVYAVDVLVSSGEGKAKDAGQRTTIYKRDPSKQYGLKMKTSRAFFSEVERRFDA 275 + F+ A++ +SG G K AG+R + M + + V+ + Sbjct: 361 SVFQAGPSTAMNWYYTSGSGDVKSAGKR-----QSNRGVAPDAMCGNAVMYDAVKGKILT 415 Query: 276 MPFTLRAFEDEKKARMGVVECAKHELLQPFNVLYEKEGEFVAQFKFTVLLMPNGPMRITS 335 + + + ++ + N ++ G + A+ T +++P+G IT Sbjct: 416 FGGSPDYQDSDATTNAHIITLGEPG--TSPNTVFASNGLYFARTFHTSVVLPDGSTFITG 473 Query: 336 G-----PFE-------PDLYKSEME 348 G PFE P++Y E + Sbjct: 474 GQRRGIPFEDSTPVFTPEIYVPEQD 498 >4V4T-BD nrPDB Length = 173 Score = 30.2 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 31/173 (17%), Positives = 57/173 (32%), Gaps = 10/173 (5%) Query: 108 IDLGVHVDGFIANVAHTFVVDVAQGTQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVT 167 ID DG VA T D + + + ++ A L K G + Sbjct: 5 IDFKRDKDGIPGRVA-TIEYDPNRSANIALINYADGEKRYIIAPKNL---KVGMEIMSGP 60 Query: 168 EAWNKVAHSFNCTPIE-GMLSHQLKQHVIDGEKTIIQNPTDQQKKDHEK----AEFEVHE 222 +A K+ ++ I G L H ++ G + + T Q E E Sbjct: 61 DADIKIGNALPLENIPVGTLVHNIELKPGRGGQLVRAAGTSAQVLGKEGKYVIVRLASGE 120 Query: 223 VYAVDVLVSSGEGKAKDAGQRTTIYKRDPSKQYGLKMKTSRAF-FSEVERRFD 274 V + + G+ + G+ + + +K + +K R + V+ F Sbjct: 121 VRMILGKCRATVGEVGNGGRTDKPFVKAGNKHHKMKAPNVRGVAMNAVDHPFG 173 >5EYT-A nrPDB Length = 497 Score = 29.8 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 14/121 (11%), Positives = 39/121 (32%), Gaps = 7/121 (5%) Query: 93 KSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGTQVTGRKADVIKAAHLCAEA 152 + D ++K +++ GF + T + I A Sbjct: 225 QGDHQKVIKLDEIL-----TKKSGFQRSWCVTGQTYPRKVDIEITNALSNIGATVHKICT 279 Query: 153 ALRLVKPGNQNTQVTEAWNKVAHSFNC--TPIEGMLSHQLKQHVIDGEKTIIQNPTDQQK 210 +RL+ ++ + E + + PI + L ++++ +++ + Q Sbjct: 280 DIRLLSSFHEVEEPFETKQIGSSAMPYKRNPIRSERACSLARYLMHISTSMVSTVSVQWL 339 Query: 211 K 211 + Sbjct: 340 E 340 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.306 0.121 0.282 Lambda K H 0.267 0.0372 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,430,123 Number of Sequences: 36641 Number of extensions: 394085 Number of successful extensions: 1236 Number of sequences better than 10.0: 41 Number of HSP's better than 10.0 without gapping: 58 Number of HSP's successfully gapped in prelim test: 25 Number of HSP's that attempted gapping in prelim test: 1058 Number of HSP's gapped (non-prelim): 110 length of query: 394 length of database: 10,336,785 effective HSP length: 99 effective length of query: 295 effective length of database: 6,709,326 effective search space: 1979251170 effective search space used: 1979251170 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.6 bits) S2: 60 (27.9 bits)