BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9UNQ2 (313 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1ZQ9-A nrPDB 580 e-166 2H1R-A nrPDB 267 5e-72 3GRV-A nrPDB 132 1e-31 3FYD-A nrPDB 129 2e-30 6IFV-A nrPDB 114 7e-26 3TQS-A nrPDB 106 1e-23 4JXJ-A nrPDB 106 1e-23 6IFX-A nrPDB 104 4e-23 3UZU-A nrPDB 100 2e-21 3FUV-A nrPDB 98 5e-21 1QYR-A nrPDB 87 1e-17 4GC9-A nrPDB 82 2e-16 3R9X-B nrPDB 64 1e-10 1YUB-A nrPDB 63 2e-10 1QAM-A nrPDB 59 3e-09 6ERQ-F nrPDB 40 0.001 6ERO-A nrPDB 40 0.001 3CJR-A nrPDB 37 0.012 2GPY-A nrPDB 37 0.012 5BXY-A nrPDB 36 0.027 3EGI-A nrPDB 35 0.034 3GDH-A nrPDB 35 0.038 4HTF-A nrPDB 34 0.081 1L3B-A nrPDB 33 0.14 5YAC-A nrPDB 33 0.15 2YR0-A nrPDB 32 0.27 2YXD-A nrPDB 32 0.32 3HNR-A nrPDB 32 0.42 1YB2-A nrPDB 31 0.67 3E23-A nrPDB 31 0.74 2B25-A nrPDB 31 0.77 4L7V-A nrPDB 31 0.79 5WP4-A nrPDB 30 0.92 1UWV-A nrPDB 30 0.92 3EGE-A nrPDB 30 1.1 1WG8-A nrPDB 30 1.2 4L9M-A nrPDB 30 1.2 3LBF-A nrPDB 30 1.4 3CBG-A nrPDB 30 1.7 1Y8C-A nrPDB 30 1.8 1VBF-A nrPDB 30 1.8 5K9N-A nrPDB 30 1.8 5XJ2-A nrPDB 30 1.8 3UVF-A nrPDB 29 2.1 1WY7-A nrPDB 29 2.2 1G6Q-1 nrPDB 29 2.5 5BP9-A nrPDB 29 2.6 5LOG-A nrPDB 29 3.2 4FZV-A nrPDB 28 3.5 5BSZ-A nrPDB 28 3.6 5WP5-A nrPDB 28 3.8 6NUW-G nrPDB 28 3.9 1G60-A nrPDB 28 3.9 5NJ3-A nrPDB 28 4.0 6BLB-A nrPDB 28 5.2 1VL5-A nrPDB 28 6.6 >1ZQ9-A nrPDB Length = 285 Score = 580 bits (1494), Expect = e-166, Method: Compositional matrix adjust. Identities = 283/283 (100%), Positives = 283/283 (100%) Query: 31 NTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRL 90 NTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRL Sbjct: 3 NTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRL 62 Query: 91 VAELHKRVQGTPVASKLQVLVGDVLKTDLPFFDTCVANLPYQISSPFVFKLLLHRPFFRC 150 VAELHKRVQGTPVASKLQVLVGDVLKTDLPFFDTCVANLPYQISSPFVFKLLLHRPFFRC Sbjct: 63 VAELHKRVQGTPVASKLQVLVGDVLKTDLPFFDTCVANLPYQISSPFVFKLLLHRPFFRC 122 Query: 151 AILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPPKVESSVVRIE 210 AILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPPKVESSVVRIE Sbjct: 123 AILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPPKVESSVVRIE 182 Query: 211 PKNPPPPINFQEWDGLVRITFVRKNKTLSAAFKSSAVQQLLEKNYRIHCSVHNIIIPEDF 270 PKNPPPPINFQEWDGLVRITFVRKNKTLSAAFKSSAVQQLLEKNYRIHCSVHNIIIPEDF Sbjct: 183 PKNPPPPINFQEWDGLVRITFVRKNKTLSAAFKSSAVQQLLEKNYRIHCSVHNIIIPEDF 242 Query: 271 SIADKIQQILTSTGFSDKRARSMDIDDFIRLLHGFNAEGIHFS 313 SIADKIQQILTSTGFSDKRARSMDIDDFIRLLHGFNAEGIHFS Sbjct: 243 SIADKIQQILTSTGFSDKRARSMDIDDFIRLLHGFNAEGIHFS 285 >2H1R-A nrPDB Length = 299 Score = 267 bits (682), Expect = 5e-72, Method: Compositional matrix adjust. Identities = 132/280 (47%), Positives = 189/280 (67%), Gaps = 6/280 (2%) Query: 35 GQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAEL 94 GQH+LKNP I++ II A ++ +D+VLE+G GTGN+TVKLL AKKV+ ++D R+++E+ Sbjct: 21 GQHLLKNPGILDKIIYAAKIKSSDIVLEIGCGTGNLTVKLLPLAKKVITIDIDSRMISEV 80 Query: 95 HKRV--QGTPVASKLQVLVGDVLKTDLPFFDTCVANLPYQISSPFVFKLLLHRPFFRCAI 152 KR +G + L+V GD +KT P FD C AN+PY+ISSP +FKL+ HRP F+CA+ Sbjct: 81 KKRCLYEG---YNNLEVYEGDAIKTVFPKFDVCTANIPYKISSPLIFKLISHRPLFKCAV 137 Query: 153 LMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPPKVESSVVRIEPK 212 LMFQ+EFA R++A GD Y RL+IN +L +V + V +++F PPPKV+S +V++ PK Sbjct: 138 LMFQKEFAERMLANVGDSNYSRLTINVKLFCKVTKVCNVNRSSFNPPPKVDSVIVKLIPK 197 Query: 213 NPPPPINFQEWDGLVRITFVRKNKTLSAAFKSSAVQQLLEKNYRIHCSVHNIIIPEDFSI 272 NF EWD L+RI F RK KTL A FK +AV +LE NY+ C++ N +P +F Sbjct: 198 ESSFLTNFDEWDNLLRICFSRKRKTLHAIFKRNAVLNMLEHNYKNWCTL-NKQVPVNFPF 256 Query: 273 ADKIQQILTSTGFSDKRARSMDIDDFIRLLHGFNAEGIHF 312 +L +KR+ ++D +DF++LL FN +GIHF Sbjct: 257 KKYCLDVLEHLDMCEKRSINLDENDFLKLLLEFNKKGIHF 296 >3GRV-A nrPDB Length = 295 Score = 132 bits (333), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 93/264 (35%), Positives = 141/264 (53%), Gaps = 19/264 (7%) Query: 26 GGLMFN--TGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVA 83 G MF +GQ L + +N ++ A L DVVLE+G G G +T +L + AKKV Sbjct: 18 GSHMFKPKKKLGQCFLIDKNFVNKAVESANLTKDDVVLEIGLGKGILTEELAKNAKKVYV 77 Query: 84 CELDPRLVAELHKRVQGTPVASKLQVLVGDVLKTDLPF--FDTCVANLPYQISSPFVFKL 141 E+D L +K + + + ++++ GD LK DL F+ VANLPYQISSP FKL Sbjct: 78 IEIDKSLEPYANKLKE---LYNNIEIIWGDALKVDLNKLDFNKVVANLPYQISSPITFKL 134 Query: 142 LLHRPFFRCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPPK 201 + + F A+LM+Q EFA R+VA G K Y RLS+ Q A V+ + KV + F P PK Sbjct: 135 I--KRGFDLAVLMYQYEFAKRMVAAAGTKDYGRLSVAVQSRADVEIVAKVPPSAFYPKPK 192 Query: 202 VESSVVRIEPKNPPPPI-NFQEWDGLVRITFVRKNKTLSAA---------FKSSAVQQLL 251 V S++V+I+P I N +D +R F +NK++ A + ++++L Sbjct: 193 VYSAIVKIKPNKGKYHIENENFFDDFLRAIFQHRNKSVRKALIDSSKELNYNKDEMKKIL 252 Query: 252 EKNYRIHCSVHNIIIPEDFSIADK 275 E + + N+I + F ++ K Sbjct: 253 EDFLNTNSEIKNLINEKVFKLSVK 276 >3FYD-A nrPDB Length = 263 Score = 129 bits (323), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 87/243 (35%), Positives = 133/243 (54%), Gaps = 17/243 (6%) Query: 45 INSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVA 104 +N ++ A L DVVLE+G G G +T +L + AKKV E+D L +K + + Sbjct: 10 VNKAVESANLTKDDVVLEIGLGKGILTEELAKNAKKVYVIEIDKSLEPYANKLKE---LY 66 Query: 105 SKLQVLVGDVLKTDLP--FFDTCVANLPYQISSPFVFKLLLHRPFFRCAILMFQREFALR 162 + ++++ GD LK DL F+ VANLPYQISSP FKL+ + F A+LM+Q EFA R Sbjct: 67 NNIEIIWGDALKVDLNKLDFNKVVANLPYQISSPITFKLI--KRGFDLAVLMYQYEFAKR 124 Query: 163 LVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPPKVESSVVRIEPKNPPPPI-NFQ 221 +VA G K Y RLS+ Q A V+ + KV + F P PKV S++V+I+P I N Sbjct: 125 MVAAAGTKDYGRLSVAVQSRADVEIVAKVPPSAFYPKPKVYSAIVKIKPNKGKYHIENEN 184 Query: 222 EWDGLVRITFVRKNKTLSAA---------FKSSAVQQLLEKNYRIHCSVHNIIIPEDFSI 272 +D +R F +NK++ A + ++++LE + + N+I + F + Sbjct: 185 FFDDFLRAIFQHRNKSVRKALIDSSKELNYNKDEMKKILEDFLNTNSEIKNLINEKVFKL 244 Query: 273 ADK 275 + K Sbjct: 245 SVK 247 >6IFV-A nrPDB Length = 215 Score = 114 bits (284), Expect = 7e-26, Method: Compositional matrix adjust. Identities = 73/206 (35%), Positives = 111/206 (53%), Gaps = 13/206 (6%) Query: 20 RELKSAGGLMFNTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAK 79 +E+ G F +GQ+ L + I+N I+D A + V+E+GPG G +T +L ++AK Sbjct: 12 KEILKKYGFSFKKSLGQNFLIDTNILNRIVDHAEVTEKTGVIEIGPGIGALTEQLAKRAK 71 Query: 80 KVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVLKTDLPF-----FDTC-----VANL 129 KVVA E+D RL+ L + +P + + V+ DVLK D+ F C VANL Sbjct: 72 KVVAFEIDQRLLPILKDTL--SPYEN-VTVIHQDVLKADVKSVIEEQFQDCDEIMVVANL 128 Query: 130 PYQISSPFVFKLLLHRPFFRCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLM 189 PY +++P + KLL + ++M Q+E A R+ A P K Y LSI Q +M Sbjct: 129 PYYVTTPIIMKLLEEHLPLKGIVVMLQKEVAERMAADPSSKEYGSLSIAVQFYTEAKTVM 188 Query: 190 KVGKNNFRPPPKVESSVVRIEPKNPP 215 V K F P P V+S+V+R+ ++ P Sbjct: 189 IVPKTVFVPQPNVDSAVIRLILRDGP 214 >3TQS-A nrPDB Length = 255 Score = 106 bits (265), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 76/258 (29%), Positives = 120/258 (46%), Gaps = 23/258 (8%) Query: 35 GQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAEL 94 GQH L + ++ I+ + TD ++E+GPG G +T LL + + E+D LVA L Sbjct: 8 GQHFLHDSFVLQKIVSAIHPQKTDTLVEIGPGRGALTDYLLTECDNLALVEIDRDLVAFL 67 Query: 95 HKRVQGTPVASKLQVLVGDVLKTDLPFFDT-----CVANLPYQISSPFVFKLLLHRPFFR 149 K+ + + D L+ D T V NLPY IS+P +F L Sbjct: 68 QKKYNQ---QKNITIYQNDALQFDFSSVKTDKPLRVVGNLPYNISTPLLFHLFSQIHCIE 124 Query: 150 CAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPPKVESSVVRI 209 M Q+E R+ A+ G Y RLS+ Q +L V F PPP+VES+++R+ Sbjct: 125 DMHFMLQKEVVRRITAEVGSHDYGRLSVMAQYFCDNTYLFTVSPQAFTPPPRVESAIIRL 184 Query: 210 EPKNPPPPI--NFQEWDGLVRITFVRKNKTLSAAFK---SSAVQQLLEKNYRIHCSVHNI 264 P++ P+ N + +V+ F + KT+ A K + + LLE N ++ Sbjct: 185 IPRHNFTPVAKNLDQLSHVVKEAFSYRRKTVGNALKKLINPSQWPLLEINPQLR------ 238 Query: 265 IIPEDFSIAD--KIQQIL 280 P++ ++ D KI IL Sbjct: 239 --PQELTVEDFVKISNIL 254 >4JXJ-A nrPDB Length = 276 Score = 106 bits (264), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 75/245 (30%), Positives = 122/245 (49%), Gaps = 13/245 (5%) Query: 35 GQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVAC-ELDPRLVAE 93 GQ+ + + + + I+ + L VLE+GPGTG +T +L K K++ E D R + Sbjct: 29 GQNFIFDGSLCDKIVRASGLEENSNVLEIGPGTGGLTRSILHKNPKLLTVIETDERCIPL 88 Query: 94 LHKRVQGTPVASKLQVLVGDVLKTDLPFFDT----CVANLPYQISSPFVFKLLLHRPFFR 149 L++ Q P L ++ D LK L +T ++NLPY I + V + L Sbjct: 89 LNEIKQYHP---NLNIIKQDALKLKLSDLNTNKITIISNLPYHIGTELVIRWLKESSLVA 145 Query: 150 CAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPPKVESSVVRI 209 LM Q+E R+ AKP K Y RLS+ L+A V+ V F PPPKV S++V++ Sbjct: 146 SMTLMLQKEVVERICAKPSTKAYGRLSVICSLIATVEKCFDVAPTAFYPPPKVYSAIVKL 205 Query: 210 EP-KNPPPPINFQEWDGLVRITFVRKNKTLSAAFKSSA--VQQLLEK-NYRIHCSVHNII 265 P +N P + + + ++ F + K + ++ K+ A + +LL K N +C N + Sbjct: 206 TPLENIPNSDLISKVELITKMAFAGRRKMIKSSLKNLAPNISELLAKLNISDNCRAEN-L 264 Query: 266 IPEDF 270 P D+ Sbjct: 265 TPNDY 269 >6IFX-A nrPDB Length = 287 Score = 104 bits (260), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 88/299 (29%), Positives = 141/299 (47%), Gaps = 41/299 (13%) Query: 20 RELKSAGGLMFNTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAK 79 +E+ G F +GQ+ L + I+N I+D A + V+E+GPG G +T +L ++AK Sbjct: 12 KEILKKYGFSFKKSLGQNFLIDTNILNRIVDHAEVTEKTGVIEIGPGIGALTEQLAKRAK 71 Query: 80 KVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVLKTDLPF-----FDTC-----VANL 129 KVVA E+D RL+ L + +P + + V+ DVLK D+ F C VANL Sbjct: 72 KVVAFEIDQRLLPILKDTL--SPYEN-VTVIHQDVLKADVKSVIEEQFQDCDEIMVVANL 128 Query: 130 PYQISSPFVFKLLLHRPFFRCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLM 189 PY +++P + KLL + ++M Q+E A R+ LSI Q +M Sbjct: 129 PYYVTTPIIMKLLEEHLPLKGIVVMLQKEVAERMANTKRS-----LSIAVQFYTEAKTVM 183 Query: 190 KVGKNNFRPPPKVESSVVRIEPKNPPPPINFQE--WDGLVRITFVRKNKTLSAAFKSSAV 247 V K F P P V+S+V+R+ ++ P E + L++ +F ++ KTL ++ Sbjct: 184 IVPKTVFVPQPNVDSAVIRLILRDGPAVDVENESFFFQLIKASFAQRRKTLLNNLVNNL- 242 Query: 248 QQLLEKNYRIHCSVHNIIIPEDFSIADKIQQILTSTGFSDK-RARSMDIDDFIRLLHGF 305 PE + I+Q+L T K R S+ I++F L +G Sbjct: 243 -------------------PEGKAQKSTIEQVLEETNIDGKRRGESLSIEEFAALSNGL 282 >3UZU-A nrPDB Length = 279 Score = 99.8 bits (247), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 71/220 (32%), Positives = 109/220 (49%), Gaps = 23/220 (10%) Query: 35 GQHILKNPLIINSIIDKAALRPT--DVVLEVGPGTGNMT----VKLLEKAKKVVACELDP 88 GQ+ L + +I++I+ AA+RP + ++E+GPG G +T +L + A ELD Sbjct: 21 GQNFLVDHGVIDAIV--AAIRPERGERMVEIGPGLGALTGPVIARLATPGSPLHAVELDR 78 Query: 89 RLVAELHKRVQGTPVASKLQVLVGDVLKTDLPFFDT--------CVANLPYQISSPFVFK 140 L+ L +R L++ GD L D + NLPY ISSP +F Sbjct: 79 DLIGRLEQRF-----GELLELHAGDALTFDFGSIARPGDEPSLRIIGNLPYNISSPLLFH 133 Query: 141 LLLHRPFFRCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPP 200 L+ P M Q E R+VA+PG K + RLS+ Q +D L+ V +F+PPP Sbjct: 134 LMSFAPVVIDQHFMLQNEVVERMVAEPGTKAFSRLSVMLQYRYVMDKLIDVPPESFQPPP 193 Query: 201 KVESSVVRIEPKNPP--PPINFQEWDGLVRITFVRKNKTL 238 KV+S++VR+ P P P ++ +V F ++ K L Sbjct: 194 KVDSAIVRMIPHAPHELPAVDPAVLGEVVTAAFSQRRKML 233 >3FUV-A nrPDB Length = 271 Score = 97.8 bits (242), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 88/294 (29%), Positives = 132/294 (44%), Gaps = 41/294 (13%) Query: 20 RELKSAGGLMFNTGIGQHILKNPLIINSIIDKAALRP-TDVVLEVGPGTGNMTVKLLEKA 78 R L GL + GQ+ L + + I++ A RP T V EVGPG G +T LLE Sbjct: 11 RALLERHGLFADKRFGQNFLVSEAHLRRIVEAA--RPFTGPVFEVGPGLGALTRALLEAG 68 Query: 79 KKVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVL---KTDLPFFDTCVANLPYQISS 135 +V A E D RL L + + G PV +++ D L ++P VANLPY I++ Sbjct: 69 AEVTAIEKDLRLRPVLEETLSGLPV----RLVFQDALLYPWEEVPQGSLLVANLPYHIAT 124 Query: 136 PFVFKLLLHRPFFRCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNN 195 P V +LL F R + + Q+E A R+ A+P Y L++ A + L + Sbjct: 125 PLVTRLLKTGRFARL-VFLVQKEVAERMTARPKTPAYGVLTLRVAHHAVAERLFDLPPGA 183 Query: 196 FRPPPKVESSVVRIEPKNP-PPPINFQEWDGLVRITFVRKNKTLSAAFKSSAVQQLLEKN 254 F PPPKV SS+VR+ P P F+ LV F ++ KTL A ++ + Sbjct: 184 FFPPPKVWSSLVRLTPTGALDDPGLFR----LVEAAFGKRRKTLLNALAAAGYPK----- 234 Query: 255 YRIHCSVHNIIIPEDFSIADKIQQILTSTGFSDK-RARSMDIDDFIRLLHGFNA 307 ++++ L + G + RA +D++ F RL G Sbjct: 235 -------------------ARVEEALRALGLPPRVRAEELDLEAFRRLREGLEG 269 >1QYR-A nrPDB Length = 252 Score = 86.7 bits (213), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 58/184 (31%), Positives = 89/184 (48%), Gaps = 12/184 (6%) Query: 36 QHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELH 95 Q+ L + +I+SI+ + ++E+GPG +T + E+ ++ ELD L A Sbjct: 1 QNFLNDQFVIDSIVSAINPQKGQAMVEIGPGLAALTEPVGERLDQLTVIELDRDLAA--- 57 Query: 96 KRVQGTP-VASKLQVLVGDVLKTDLPFFDT-------CVANLPYQISSPFVFKLLLHRPF 147 R+Q P + KL + D + + NLPY IS+P +F L + Sbjct: 58 -RLQTHPFLGPKLTIYQQDAMTFNFGELAEKMGQPLRVFGNLPYNISTPLMFHLFSYTDA 116 Query: 148 FRCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPPKVESSVV 207 M Q+E RLVA P K Y RLS+ Q V +++V + F PPPKV+S+VV Sbjct: 117 IADMHFMLQKEVVNRLVAGPNSKAYGRLSVMAQYYCNVIPVLEVPPSAFTPPPKVDSAVV 176 Query: 208 RIEP 211 R+ P Sbjct: 177 RLVP 180 >4GC9-A nrPDB Length = 345 Score = 82.4 bits (202), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 68/216 (31%), Positives = 96/216 (44%), Gaps = 26/216 (12%) Query: 20 RELKSAGGLMFNTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLE-KA 78 RE+ GL + Q+ L + + + I+ KA V EVGPG G +T +L Sbjct: 19 REIIKLFGLRAVKQLSQNFLLDLRLTDKIVRKAGSLADVYVYEVGPGPGGITRSILNANV 78 Query: 79 KKVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVLK---------------TDLPFFD 123 +++ E D R + L P KL+++ GDVL D P Sbjct: 79 AELLVVEKDTRFIPGLQMLSDAAP--GKLRIVHGDVLTYKIEKAFPGNIRRQWEDDPPNV 136 Query: 124 TCVANLPYQISSPFVFKLLLH-----RPFFRC---AILMFQREFALRLVAKPGDKLYCRL 175 + NLP+ +S+P + K L + PF L FQ+E A RLVA G K + RL Sbjct: 137 HIIGNLPFSVSTPLIIKWLENISLKDGPFVYGRTKMTLTFQKEVAERLVATTGSKQHSRL 196 Query: 176 SINTQLLARVDHLMKVGKNNFRPPPKVESSVVRIEP 211 SI Q L V+HL + F P PKV+ VV + P Sbjct: 197 SIMAQYLCNVEHLFTIPGKAFVPKPKVDVGVVHLTP 232 >3R9X-B nrPDB Length = 248 Score = 63.5 bits (153), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 60/210 (28%), Positives = 101/210 (48%), Gaps = 16/210 (7%) Query: 35 GQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEK-AKKVVACELDPRLVAE 93 GQH+L + ++ I ++ + + V+EVG GTGN+T LL+ KK+ ELD +V Sbjct: 9 GQHLLVSEGVLKKIAEELNIEEGNTVVEVGGGTGNLTKVLLQHPLKKLYVIELDREMVEN 68 Query: 94 LHKRVQGTPVASKLQVLVGDVLKTDLPFFD-----TCVANLPYQISSPFVFKLLLHRPFF 148 L + +L+V+ D K PF V NLPY ++S + + ++ Sbjct: 69 LK-----SIGDERLEVINEDASK--FPFCSLGKELKVVGNLPYNVASLIIENTVYNKDCV 121 Query: 149 RCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPPKVESSVVR 208 A+ M Q+E A +L G K LS+ + V+++M V F PPPKV+S+V++ Sbjct: 122 PLAVFMVQKEVAEKL---QGKKDTGWLSVFVRTFYDVNYVMTVPPRFFVPPPKVQSAVIK 178 Query: 209 IEPKNPPPPINFQEWDGLVRITFVRKNKTL 238 + P + + + + F + K L Sbjct: 179 LVKNEKFPVKDLKNYKKFLTKIFQNRRKVL 208 >1YUB-A nrPDB Length = 245 Score = 62.8 bits (151), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 59/247 (23%), Positives = 111/247 (44%), Gaps = 40/247 (16%) Query: 31 NTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRL 90 N Q+ L + ++N II + L+ TD V E+G G G++T KL + +K+V + ELD L Sbjct: 4 NIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLTTKLAKISKQVTSIELDSHL 63 Query: 91 VAELHKRVQGTPVASKLQVLVGDVLKTDLPFFD--TCVANLPYQISSPFVFKLLLHRPFF 148 ++++ + +++ ++ D+L+ P V N+PY +S+ + K++ Sbjct: 64 FNLSSEKLK---LNTRVTLIHQDILQFQFPNKQRYKIVGNIPYHLSTQIIKKVVFE---- 116 Query: 149 RCAILMFQREFALRLVAKPGDKLYCR---------LSINTQLLARVDHLMKVGKNNFRPP 199 R + L+ + G Y R L ++TQ+ + L+K+ F P Sbjct: 117 -------SRASDIYLIVEEG--FYKRTLDIHRTLGLLLHTQV--SIQQLLKLPAECFHPK 165 Query: 200 PKVESSVVRIEPKNPPPPINFQEWDGLVRITFVRK--NKTLSAAFKSSAVQQLLEKNYRI 257 PKV S ++++ P + W + FV K N+ F + Q ++ Sbjct: 166 PKVNSVLIKLTRHTTDVPDKY--WK--LYTYFVSKWVNREYRQLFTKNQFHQAMK----- 216 Query: 258 HCSVHNI 264 H V+N+ Sbjct: 217 HAKVNNL 223 >1QAM-A nrPDB Length = 244 Score = 58.9 bits (141), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 51/186 (27%), Positives = 85/186 (45%), Gaps = 15/186 (8%) Query: 31 NTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRL 90 N Q+ + + I+ I+ L D + E+G G G+ T++L+++ V A E+D +L Sbjct: 5 NIKHSQNFITSKHNIDKIMTNIRLNEHDNIFEIGSGKGHFTLELVQRCNFVTAIEIDHKL 64 Query: 91 VAELHKRVQGTPVASKLQVLVGDVLKTDLPFFDT--CVANLPYQISSPFVFKLLLHRPFF 148 ++ QVL D+L+ P + N+PY IS+ + K++ Sbjct: 65 CKTTENKLVD---HDNFQVLNKDILQFKFPKNQSYKIFGNIPYNISTDIIRKIVF-DSIA 120 Query: 149 RCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVD--HLMKVGKNNFRPPPKVESSV 206 L+ + FA RL L + S+ L+A VD L V + F P PKV SS+ Sbjct: 121 DEIYLIVEYGFAKRL-------LNTKRSLALFLMAEVDISILSMVPREYFHPKPKVNSSL 173 Query: 207 VRIEPK 212 +R+ K Sbjct: 174 IRLNRK 179 >6ERQ-F nrPDB Length = 377 Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust. Identities = 25/64 (39%), Positives = 32/64 (50%), Gaps = 2/64 (3%) Query: 55 RPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGDV 114 RP ++LE PG G +T LLE KVVA E D + H G + KL+V+ D Sbjct: 75 RPPHLLLECNPGPGILTQALLEAGAKVVALESDKTFIP--HLESLGKNLDGKLRVIHCDF 132 Query: 115 LKTD 118 K D Sbjct: 133 FKLD 136 >6ERO-A nrPDB Length = 313 Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust. Identities = 25/64 (39%), Positives = 32/64 (50%), Gaps = 2/64 (3%) Query: 55 RPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGDV 114 RP ++LE PG G +T LLE KVVA E D + H G + KL+V+ D Sbjct: 34 RPPHLLLECNPGPGILTQALLEAGAKVVALESDKTFIP--HLESLGKNLDGKLRVIHCDF 91 Query: 115 LKTD 118 K D Sbjct: 92 FKLD 95 >3CJR-A nrPDB Length = 254 Score = 37.0 bits (84), Expect = 0.012, Method: Compositional matrix adjust. Identities = 33/113 (29%), Positives = 56/113 (49%), Gaps = 14/113 (12%) Query: 27 GLMFNTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACEL 86 G+ F TG H L + ++ LRP D VL++G G+G + + + K + ++ Sbjct: 96 GMAFGTG---HHETTRLALKALARH--LRPGDKVLDLGTGSGVLAIAAEKLGGKALGVDI 150 Query: 87 DPRLV--AELHKRVQGTPVASKLQVLVGDVLKTDLPF--FDTCVANLPYQISS 135 DP ++ AE + + G + + L G L+ LPF FD VANL ++ + Sbjct: 151 DPMVLPQAEANAKRNGV----RPRFLEGS-LEAALPFGPFDLLVANLYAELHA 198 >2GPY-A nrPDB Length = 233 Score = 37.0 bits (84), Expect = 0.012, Method: Compositional matrix adjust. Identities = 22/73 (30%), Positives = 37/73 (50%), Gaps = 7/73 (9%) Query: 60 VLEVGPGTGNMTVKLLEK--AKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVL-- 115 +LE+G G +++ + +V+ E D R E HK V+ + S++++L GD L Sbjct: 58 ILEIGTAIGYSAIRMAQALPEATIVSIERDERRYEEAHKHVKALGLESRIELLFGDALQL 117 Query: 116 --KTDL-PFFDTC 125 K +L P FD Sbjct: 118 GEKLELYPLFDVL 130 >5BXY-A nrPDB Length = 158 Score = 35.8 bits (81), Expect = 0.027, Method: Compositional matrix adjust. Identities = 19/77 (24%), Positives = 41/77 (53%), Gaps = 1/77 (1%) Query: 44 IINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEK-AKKVVACELDPRLVAELHKRVQGTP 102 +++ +++ A + TDV+ ++G G G + ++ + V E+DP LV + K + Sbjct: 12 VVDRMLELADVDETDVLYDLGSGDGRIVIRAARTHGARGVGIEIDPDLVKKARKNAKEAG 71 Query: 103 VASKLQVLVGDVLKTDL 119 VA ++ GD+ + D+ Sbjct: 72 VADLVEFRQGDLFEADI 88 >3EGI-A nrPDB Length = 206 Score = 35.4 bits (80), Expect = 0.034, Method: Compositional matrix adjust. Identities = 21/93 (22%), Positives = 40/93 (43%), Gaps = 6/93 (6%) Query: 58 DVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGD---- 113 DVV++ G G T++ +V+A ++DP +A + +A K++ + GD Sbjct: 45 DVVVDAFCGVGGNTIQFALTGMRVIAIDIDPVKIALARNNAEVYGIADKIEFICGDFLLL 104 Query: 114 --VLKTDLPFFDTCVANLPYQISSPFVFKLLLH 144 LK D+ F Y + F + ++ Sbjct: 105 ASFLKADVVFLSPPWGGPDYATAETFDIRTMMS 137 >3GDH-A nrPDB Length = 241 Score = 35.0 bits (79), Expect = 0.038, Method: Compositional matrix adjust. Identities = 21/93 (22%), Positives = 40/93 (43%), Gaps = 6/93 (6%) Query: 58 DVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGD---- 113 DVV++ G G T++ +V+A ++DP +A + +A K++ + GD Sbjct: 80 DVVVDAFCGVGGNTIQFALTGMRVIAIDIDPVKIALARNNAEVYGIADKIEFICGDFLLL 139 Query: 114 --VLKTDLPFFDTCVANLPYQISSPFVFKLLLH 144 LK D+ F Y + F + ++ Sbjct: 140 ASFLKADVVFLSPPWGGPDYATAETFDIRTMMS 172 >4HTF-A nrPDB Length = 285 Score = 34.3 bits (77), Expect = 0.081, Method: Compositional matrix adjust. Identities = 12/51 (23%), Positives = 27/51 (52%) Query: 60 VLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKLQVL 110 VL+ G G G +K+ E+ +V+ C+L +++ + + V+ +Q + Sbjct: 72 VLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFI 122 >1L3B-A nrPDB Length = 192 Score = 33.5 bits (75), Expect = 0.14, Method: Compositional matrix adjust. Identities = 15/56 (26%), Positives = 32/56 (57%) Query: 58 DVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGD 113 DV ++VG GTG +T++L + ++V A + +P ++ +Q + + ++ GD Sbjct: 35 DVAVDVGCGTGGVTLELAGRVRRVYAIDRNPEAISTTEMNLQRHGLGDNVTLMEGD 90 >5YAC-A nrPDB Length = 346 Score = 33.1 bits (74), Expect = 0.15, Method: Compositional matrix adjust. Identities = 20/73 (27%), Positives = 41/73 (56%), Gaps = 2/73 (2%) Query: 58 DVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVLKT 117 +VV ++ G G ++ L +KA+ V AC+++P + L + ++ V + + +L GD + Sbjct: 200 EVVFDMFAGVGPFSILLAKKAELVFACDINPWAIKYLEENIKLNKVNNVVPIL-GDSREI 258 Query: 118 DLPFFDTCVANLP 130 ++ D + NLP Sbjct: 259 EVK-ADRIIMNLP 270 >2YR0-A nrPDB Length = 263 Score = 32.3 bits (72), Expect = 0.27, Method: Compositional matrix adjust. Identities = 18/62 (29%), Positives = 33/62 (53%), Gaps = 2/62 (3%) Query: 59 VVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVLKTD 118 V LE+G GTG + + L+ + + +A + D ++ +++ G V K+QV+ D Sbjct: 42 VFLELGVGTGRIALPLIARGYRYIALDADAAMLEVFRQKIAG--VDRKVQVVQADARAIP 99 Query: 119 LP 120 LP Sbjct: 100 LP 101 >2YXD-A nrPDB Length = 183 Score = 32.0 bits (71), Expect = 0.32, Method: Compositional matrix adjust. Identities = 16/37 (43%), Positives = 24/37 (64%) Query: 49 IDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACE 85 I K L DVV++VG G+G MTV++ ++ K V A + Sbjct: 28 IGKLNLNKDDVVVDVGCGSGGMTVEIAKRCKFVYAID 64 >3HNR-A nrPDB Length = 220 Score = 31.6 bits (70), Expect = 0.42, Method: Compositional matrix adjust. Identities = 23/76 (30%), Positives = 36/76 (47%), Gaps = 10/76 (13%) Query: 60 VLEVGPGTGNMTVKLLEKAKKVVACE--LDPRLVAELHKRVQGTPVASKLQVLVGDVLKT 117 VLE G GTGN+T KLL + V E + R++A+ + + + GD L Sbjct: 49 VLEFGVGTGNLTNKLLLAGRTVYGIEPSREMRMIAK-------EKLPKEFSITEGDFLSF 101 Query: 118 DLPF-FDTCVANLPYQ 132 ++P DT V+ + Sbjct: 102 EVPTSIDTIVSTYAFH 117 >1YB2-A nrPDB Length = 275 Score = 31.2 bits (69), Expect = 0.67, Method: Compositional matrix adjust. Identities = 19/46 (41%), Positives = 27/46 (58%), Gaps = 5/46 (10%) Query: 35 GQHILKNPLIINSI-----IDKAALRPTDVVLEVGPGTGNMTVKLL 75 G+ I +N II+ I I + LRP +LEVG G+GNM+ +L Sbjct: 84 GRVIRRNTQIISEIDASYIIMRCGLRPGMDILEVGVGSGNMSSYIL 129 >3E23-A nrPDB Length = 211 Score = 30.8 bits (68), Expect = 0.74, Method: Compositional matrix adjust. Identities = 20/71 (28%), Positives = 33/71 (46%), Gaps = 1/71 (1%) Query: 60 VLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVLKTDL 119 +LE+G G G +L V A + P L AE +R+ G PV + L + + D Sbjct: 47 ILELGCGAGYQAEAMLAAGFDVDATDGSPELAAEASRRL-GRPVRTMLFHQLDAIDAYDA 105 Query: 120 PFFDTCVANLP 130 + C+ ++P Sbjct: 106 VWAHACLLHVP 116 >2B25-A nrPDB Length = 336 Score = 30.8 bits (68), Expect = 0.77, Method: Compositional matrix adjust. Identities = 16/37 (43%), Positives = 21/37 (56%), Gaps = 1/37 (2%) Query: 42 PLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKA 78 P IN I+ + P D VLE G G+G M++ L KA Sbjct: 91 PKDINMILSMMDINPGDTVLEAGSGSGGMSL-FLSKA 126 >4L7V-A nrPDB Length = 225 Score = 30.8 bits (68), Expect = 0.79, Method: Compositional matrix adjust. Identities = 18/53 (33%), Positives = 25/53 (47%), Gaps = 1/53 (1%) Query: 34 IGQ-HILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACE 85 IGQ + P I+ + + AL P VLE+G G+G T L + V E Sbjct: 69 IGQGQTISQPYIVAKMTELLALTPETKVLEIGTGSGYQTAVLAKLVNHVFTVE 121 >5WP4-A nrPDB Length = 491 Score = 30.4 bits (67), Expect = 0.92, Method: Compositional matrix adjust. Identities = 23/92 (25%), Positives = 41/92 (44%), Gaps = 3/92 (3%) Query: 21 ELKSAGGLMFNTGIGQHILKNPLI--INSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKA 78 + KS+G L + GQ + + ++K L+P VL+VG G G + EK Sbjct: 245 QYKSSGILRYERVFGQGFVSTGGLETTKEFVEKMNLKPGQKVLDVGCGIGGGDFYMAEKF 304 Query: 79 K-KVVACELDPRLVAELHKRVQGTPVASKLQV 109 VV +L +++ +R G + + +V Sbjct: 305 DVHVVGIDLSVNMISFALERAIGLSCSVEFEV 336 >1UWV-A nrPDB Length = 433 Score = 30.4 bits (67), Expect = 0.92, Method: Compositional matrix adjust. Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 6/64 (9%) Query: 28 LMFNTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELD 87 + N G+ Q ++ L +D ++P D VL++ G GN T+ L +A VV E Sbjct: 264 IQVNAGVNQKMVARAL---EWLD---VQPEDRVLDLFCGMGNFTLPLATQAASVVGVEGV 317 Query: 88 PRLV 91 P LV Sbjct: 318 PALV 321 >3EGE-A nrPDB Length = 261 Score = 30.4 bits (67), Expect = 1.1, Method: Compositional matrix adjust. Identities = 15/42 (35%), Positives = 23/42 (54%) Query: 44 IINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACE 85 I+N+II+ L V+ ++G GTG +V L + V A E Sbjct: 22 IVNAIINLLNLPKGSVIADIGAGTGGYSVALANQGLFVYAVE 63 >1WG8-A nrPDB Length = 285 Score = 30.0 bits (66), Expect = 1.2, Method: Compositional matrix adjust. Identities = 14/51 (27%), Positives = 25/51 (49%) Query: 42 PLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVA 92 P++ +D A+RP V ++ G +LE+ +V+ + DP VA Sbjct: 8 PVLYQEALDLLAVRPGGVYVDATLGGAGHARGILERGGRVIGLDQDPEAVA 58 >4L9M-A nrPDB Length = 559 Score = 30.0 bits (66), Expect = 1.2, Method: Compositional matrix adjust. Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 2/72 (2%) Query: 162 RLVAKPGDKLYCRLSINTQLLAR--VDHLMKVGKNNFRPPPKVESSVVRIEPKNPPPPIN 219 LV G++L+CRL TQ+ AR L + K+N KV +EP+ + Sbjct: 107 ELVKAKGEELHCRLIDTTQINARDWSRKLTQRIKSNTSKKRKVSLLFDHLEPEELSEHLT 166 Query: 220 FQEWDGLVRITF 231 + E+ RI+F Sbjct: 167 YLEFKSFRRISF 178 >3LBF-A nrPDB Length = 210 Score = 30.0 bits (66), Expect = 1.4, Method: Compositional matrix adjust. Identities = 19/65 (29%), Positives = 29/65 (44%), Gaps = 1/65 (1%) Query: 21 ELKSAGGLMFNTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKK 80 E K+ + G GQ I P ++ + + L P VLE+G G+G T L + Sbjct: 43 EQKAWDNIALPIGQGQTI-SQPYMVARMTELLELTPQSRVLEIGTGSGYQTAILAHLVQH 101 Query: 81 VVACE 85 V + E Sbjct: 102 VCSVE 106 >3CBG-A nrPDB Length = 232 Score = 29.6 bits (65), Expect = 1.7, Method: Compositional matrix adjust. Identities = 27/93 (29%), Positives = 38/93 (40%), Gaps = 18/93 (19%) Query: 60 VLEVGPGTGNMTVKL---LEKAKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVLK 116 VLE+G G + + L +++AC+ DP A K Q VA K+ + +G L Sbjct: 76 VLEIGVFRGYSALAMALQLPPDGQIIACDQDPNATAIAKKYWQKAGVAEKISLRLGPALA 135 Query: 117 T-------------DLPFFDTCVANLP--YQIS 134 T DL F D N P Y+I Sbjct: 136 TLEQLTQGKPLPEFDLIFIDADKRNYPRYYEIG 168 >1Y8C-A nrPDB Length = 246 Score = 29.6 bits (65), Expect = 1.8, Method: Compositional matrix adjust. Identities = 14/50 (28%), Positives = 25/50 (50%) Query: 58 DVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKL 107 D L++ GTGN+T L K K A +L +++E + + + +L Sbjct: 39 DDYLDLACGTGNLTENLCPKFKNTWAVDLSQEMLSEAENKFRSQGLKPRL 88 >1VBF-A nrPDB Length = 231 Score = 29.6 bits (65), Expect = 1.8, Method: Compositional matrix adjust. Identities = 14/43 (32%), Positives = 24/43 (55%) Query: 48 IIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRL 90 ++D+ L VLE+G G G T + E KVV+ E++ ++ Sbjct: 62 MLDELDLHKGQKVLEIGTGIGYYTALIAEIVDKVVSVEINEKM 104 >5K9N-A nrPDB Length = 216 Score = 29.6 bits (65), Expect = 1.8, Method: Compositional matrix adjust. Identities = 20/46 (43%), Positives = 25/46 (54%), Gaps = 7/46 (15%) Query: 159 FALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPPKVES 204 ++ RLV + G +L INT L VDHL G+ RPPP ES Sbjct: 170 YSARLVQRLGYQL-----INT--LRYVDHLDASGQQVIRPPPPHES 208 >5XJ2-A nrPDB Length = 454 Score = 29.6 bits (65), Expect = 1.8, Method: Compositional matrix adjust. Identities = 15/53 (28%), Positives = 26/53 (49%) Query: 44 IINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHK 96 + + ID A L+ DV+++ G G + + + + K+V EL P V K Sbjct: 292 LYQTAIDFAELKKDDVIIDAYSGIGTIGLSVAKHVKEVYGVELIPEAVENSQK 344 >3UVF-A nrPDB Length = 255 Score = 29.3 bits (64), Expect = 2.1, Method: Compositional matrix adjust. Identities = 17/55 (30%), Positives = 28/55 (50%), Gaps = 5/55 (9%) Query: 164 VAKPGDKLYCRLSI-----NTQLLARVDHLMKVGKNNFRPPPKVESSVVRIEPKN 213 + K G L L I + QL+ ++ ++ VGK +FR ++E +RI KN Sbjct: 22 ITKKGKYLTYELGIELSIKDVQLIYKIKDILGVGKVSFRKRNEIEMVSLRIRDKN 76 >1WY7-A nrPDB Length = 207 Score = 29.3 bits (64), Expect = 2.2, Method: Compositional matrix adjust. Identities = 26/88 (29%), Positives = 42/88 (47%), Gaps = 9/88 (10%) Query: 59 VVLEVGPGTGNMTV-KLLEKAKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVLKT 117 VV ++G GTG ++ LL AK+V+ E+D V L + + K +V +GDV + Sbjct: 52 VVADLGAGTGVLSYGALLLGAKEVICVEVDKEAVDVLIENL--GEFKGKFKVFIGDVSEF 109 Query: 118 DLPFFDTCVANLPY-----QISSPFVFK 140 + D + N P+ PF+ K Sbjct: 110 N-SRVDIVIMNPPFGSQRKHADRPFLLK 136 >1G6Q-1 nrPDB Length = 328 Score = 29.3 bits (64), Expect = 2.5, Method: Compositional matrix adjust. Identities = 23/78 (29%), Positives = 40/78 (51%), Gaps = 4/78 (5%) Query: 46 NSIIDKAALRPTDVVLEVGPGTGNMTVKLLEK-AKKVVACELDPRLVAELHKR-VQGTPV 103 N+II L +VL+VG GTG +++ + AK V+ ++ + E+ K V+ Sbjct: 28 NAIIQNKDLFKDKIVLDVGCGTGILSMFAAKHGAKHVIGVDMSS--IIEMAKELVELNGF 85 Query: 104 ASKLQVLVGDVLKTDLPF 121 + K+ +L G + LPF Sbjct: 86 SDKITLLRGKLEDVHLPF 103 >5BP9-A nrPDB Length = 281 Score = 28.9 bits (63), Expect = 2.6, Method: Compositional matrix adjust. Identities = 14/42 (33%), Positives = 25/42 (59%), Gaps = 1/42 (2%) Query: 48 IIDKAALR-PTDVVLEVGPGTGNMTVKLLEKAKKVVACELDP 88 ++++ AL T +L+VG G+G + L E K+V A ++ P Sbjct: 92 LLERTALAMATGTILDVGAGSGCHALALQESGKEVSAIDISP 133 >5LOG-A nrPDB Length = 233 Score = 28.9 bits (63), Expect = 3.2, Method: Compositional matrix adjust. Identities = 19/57 (33%), Positives = 29/57 (50%), Gaps = 3/57 (5%) Query: 60 VLEVGPGTGNMTV---KLLEKAKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGD 113 LEVG TG T+ L +V+AC+L V+ + Q VA +++V +GD Sbjct: 63 TLEVGVFTGYSTLCTALALPADGRVIACDLSEEWVSIARRYWQRAGVADRIEVRLGD 119 >4FZV-A nrPDB Length = 359 Score = 28.5 bits (62), Expect = 3.5, Method: Compositional matrix adjust. Identities = 15/46 (32%), Positives = 25/46 (54%), Gaps = 2/46 (4%) Query: 53 ALRPTDVVLEVGPGTGNMTVKLLEKA--KKVVACELDPRLVAELHK 96 L+P D+VL++ G T+ LL+ + + A +L P +A L K Sbjct: 145 GLQPGDIVLDLCAAPGGKTLALLQTGCCRNLAANDLSPSRIARLQK 190 >5BSZ-A nrPDB Length = 250 Score = 28.5 bits (62), Expect = 3.6, Method: Compositional matrix adjust. Identities = 14/44 (31%), Positives = 21/44 (47%) Query: 60 VLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPV 103 +L+V GTG L+E EL P + A +++ TPV Sbjct: 51 LLDVACGTGEHLAHLVEHFPDAAGVELSPAMRAAAERKLTATPV 94 >5WP5-A nrPDB Length = 491 Score = 28.5 bits (62), Expect = 3.8, Method: Compositional matrix adjust. Identities = 18/67 (26%), Positives = 31/67 (46%), Gaps = 3/67 (4%) Query: 60 VLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVLKTDL 119 VLE+G G G T +L +KA +V+A + + + + K ++ + DV DL Sbjct: 57 VLELGAGIGRFTGELAQKAGEVIALDF---IESAIQKNESVNGHYKNIKFMCADVTSPDL 113 Query: 120 PFFDTCV 126 D + Sbjct: 114 KIKDGSI 120 >6NUW-G nrPDB Length = 241 Score = 28.5 bits (62), Expect = 3.9, Method: Compositional matrix adjust. Identities = 12/27 (44%), Positives = 19/27 (70%) Query: 90 LVAELHKRVQGTPVASKLQVLVGDVLK 116 L +EL RV+G P ++ ++ L+ DVLK Sbjct: 96 LGSELRNRVEGEPQSTSIERLIEDVLK 122 >1G60-A nrPDB Length = 260 Score = 28.5 bits (62), Expect = 3.9, Method: Compositional matrix adjust. Identities = 13/57 (22%), Positives = 27/57 (47%) Query: 37 HILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAE 93 HI P + I +A+ P D+VL+ G+G + + + + C+++ V + Sbjct: 193 HITPKPRDLIERIIRASSNPNDLVLDCFMGSGTTAIVAKKLGRNFIGCDMNAEYVNQ 249 >5NJ3-A nrPDB Length = 664 Score = 28.5 bits (62), Expect = 4.0, Method: Compositional matrix adjust. Identities = 36/136 (26%), Positives = 52/136 (38%), Gaps = 24/136 (17%) Query: 145 RPFFRCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPPKVES 204 + F A+L F R+ K G L CR + ++L+ ++ +MK G N P Sbjct: 38 KAFTEGAVLSFHN-ICYRVKLKSG-FLPCRKPVEKEILSNINGIMKPGLNAILGPTGGGK 95 Query: 205 S------VVRIEPK---------NPPPPINFQEWDGLV-------RITFVRKNKTLSAAF 242 S R +P P P NF+ G V VR+N SAA Sbjct: 96 SSLLDVLAARKDPSGLSGDVLINGAPRPANFKCNSGYVVQDDVVMGTLTVRENLQFSAAL 155 Query: 243 KSSAVQQLLEKNYRIH 258 + + EKN RI+ Sbjct: 156 RLATTMTNHEKNERIN 171 >6BLB-A nrPDB Length = 355 Score = 28.1 bits (61), Expect = 5.2, Method: Compositional matrix adjust. Identities = 11/35 (31%), Positives = 25/35 (71%), Gaps = 1/35 (2%) Query: 74 LLEKAKKVVACELDPRLVAELHKRVQGTP-VASKL 107 ++ ++ ++ E++P+ AE+ KR +GTP +A++L Sbjct: 196 IVSRSAGILGLEIEPQGAAEIAKRARGTPRIANRL 230 >1VL5-A nrPDB Length = 260 Score = 27.7 bits (60), Expect = 6.6, Method: Compositional matrix adjust. Identities = 20/72 (27%), Positives = 36/72 (50%), Gaps = 3/72 (4%) Query: 52 AALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKLQVLV 111 AAL+ + VL+V G G++ KKVVA +L ++ ++G +++ + Sbjct: 33 AALKGNEEVLDVATGGGHVANAFAPFVKKVVAFDLTEDILKVARAFIEGNG-HQQVEYVQ 91 Query: 112 GDVLKTDLPFFD 123 GD + +PF D Sbjct: 92 GDAEQ--MPFTD 101 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1ZQ9-A nrPDB 367 e-102 2H1R-A nrPDB 337 5e-93 3TQS-A nrPDB 268 2e-72 3GRV-A nrPDB 268 2e-72 6IFX-A nrPDB 263 7e-71 3FUV-A nrPDB 262 2e-70 3FYD-A nrPDB 257 4e-69 3UZU-A nrPDB 251 2e-67 4JXJ-A nrPDB 250 7e-67 1QYR-A nrPDB 247 5e-66 6IFV-A nrPDB 236 1e-62 4GC9-A nrPDB 219 1e-57 3R9X-B nrPDB 189 1e-48 1YUB-A nrPDB 189 2e-48 1QAM-A nrPDB 181 5e-46 6ERO-A nrPDB 94 1e-19 6ERQ-F nrPDB 89 2e-18 Sequences not found previously or not previously below threshold: 1L3B-A nrPDB 54 1e-07 3HNR-A nrPDB 49 3e-06 5BXY-A nrPDB 48 4e-06 1VBF-A nrPDB 48 6e-06 4IV8-A nrPDB 46 2e-05 2YXD-A nrPDB 46 2e-05 3DMF-A nrPDB 44 6e-05 4MWZ-A nrPDB 44 8e-05 4FGZ-A nrPDB 44 1e-04 3EGE-A nrPDB 44 1e-04 4L7V-A nrPDB 43 2e-04 3LBF-A nrPDB 42 4e-04 3LGA-A nrPDB 42 4e-04 2YVL-A nrPDB 42 5e-04 5WP4-A nrPDB 40 0.001 2GPY-A nrPDB 40 0.001 1G6Q-1 nrPDB 40 0.002 3CCF-A nrPDB 40 0.002 4O29-A nrPDB 40 0.002 3NTV-A nrPDB 39 0.002 5EQJ-B nrPDB 39 0.002 4M36-A nrPDB 39 0.004 5EKU-A nrPDB 38 0.004 3DLC-A nrPDB 38 0.004 1YB2-A nrPDB 38 0.005 3OFK-A nrPDB 38 0.005 1UWV-A nrPDB 38 0.005 5WP5-A nrPDB 38 0.005 3BUS-A nrPDB 38 0.006 4HGY-A nrPDB 37 0.007 1Y8C-A nrPDB 37 0.013 5IS8-A nrPDB 37 0.015 4IKP-A nrPDB 37 0.015 3B3J-A nrPDB 37 0.015 3CJR-A nrPDB 36 0.018 3EVZ-A nrPDB 36 0.019 1JG3-A nrPDB 36 0.020 2YXE-A nrPDB 36 0.021 5FAD-A nrPDB 36 0.022 6CU3-A nrPDB 36 0.024 2YR0-A nrPDB 36 0.024 3GDH-A nrPDB 36 0.026 3EGI-A nrPDB 36 0.026 5JMQ-A nrPDB 35 0.033 3R0Q-C nrPDB 35 0.037 3BKX-A nrPDB 35 0.054 2B25-A nrPDB 35 0.054 5GM1-A nrPDB 34 0.065 5DST-A nrPDB 34 0.067 3SM3-A nrPDB 34 0.069 1I9G-A nrPDB 34 0.075 4INE-A nrPDB 34 0.085 2PJD-A nrPDB 34 0.10 5KPG-A nrPDB 34 0.12 6BQC-A nrPDB 34 0.13 2IP2-A nrPDB 34 0.13 2IFT-A nrPDB 33 0.15 3DOU-A nrPDB 33 0.15 2B3T-A nrPDB 33 0.16 3X0D-A nrPDB 33 0.16 4KRG-A nrPDB 33 0.16 5U8S-7 nrPDB 33 0.19 5I2H-A nrPDB 33 0.19 4QDJ-A nrPDB 33 0.20 3TM5-A nrPDB 32 0.23 4MTL-A nrPDB 32 0.23 3D2L-A nrPDB 32 0.28 3MGG-A nrPDB 32 0.30 5XJ2-A nrPDB 32 0.30 5ZW4-A nrPDB 32 0.32 3SVZ-A nrPDB 32 0.33 2P35-A nrPDB 32 0.41 3HM2-A nrPDB 32 0.43 3JWJ-A nrPDB 32 0.43 3Q7E-A nrPDB 32 0.44 3G5T-A nrPDB 32 0.45 6MRO-A nrPDB 32 0.47 4OA5-A nrPDB 31 0.57 6GKZ-A nrPDB 31 0.62 3L8D-A nrPDB 31 0.68 3NJR-A nrPDB 31 0.68 1MJF-A nrPDB 31 0.70 4G56-A nrPDB 31 0.73 1F3L-A nrPDB 31 0.75 4RYL-A nrPDB 31 0.77 5EGS-A nrPDB 30 0.87 3LPM-A nrPDB 30 0.87 3OU6-A nrPDB 30 0.93 1P91-A nrPDB 30 0.95 3LST-A nrPDB 30 1.2 2GLU-A nrPDB 30 1.3 3OH9-A nrPDB 30 1.5 5FA5-A nrPDB 30 1.6 4LWO-B nrPDB 30 1.7 4X3Q-A nrPDB 30 1.8 5LV5-A nrPDB 29 2.1 1C3X-A nrPDB 29 2.4 2PWY-A nrPDB 29 2.6 4KDR-A nrPDB 29 2.7 4KDC-A nrPDB 29 2.7 4FZV-A nrPDB 29 2.7 1P22-B nrPDB 29 3.3 5BSZ-A nrPDB 29 3.5 4C6Y-A nrPDB 29 3.8 5LP5-A nrPDB 28 4.5 2PBF-A nrPDB 27 7.6 3PTW-A nrPDB 27 10.0 >1ZQ9-A nrPDB Length = 285 Score = 367 bits (941), Expect = e-102, Method: Composition-based stats. Identities = 283/283 (100%), Positives = 283/283 (100%) Query: 31 NTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRL 90 NTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRL Sbjct: 3 NTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRL 62 Query: 91 VAELHKRVQGTPVASKLQVLVGDVLKTDLPFFDTCVANLPYQISSPFVFKLLLHRPFFRC 150 VAELHKRVQGTPVASKLQVLVGDVLKTDLPFFDTCVANLPYQISSPFVFKLLLHRPFFRC Sbjct: 63 VAELHKRVQGTPVASKLQVLVGDVLKTDLPFFDTCVANLPYQISSPFVFKLLLHRPFFRC 122 Query: 151 AILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPPKVESSVVRIE 210 AILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPPKVESSVVRIE Sbjct: 123 AILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPPKVESSVVRIE 182 Query: 211 PKNPPPPINFQEWDGLVRITFVRKNKTLSAAFKSSAVQQLLEKNYRIHCSVHNIIIPEDF 270 PKNPPPPINFQEWDGLVRITFVRKNKTLSAAFKSSAVQQLLEKNYRIHCSVHNIIIPEDF Sbjct: 183 PKNPPPPINFQEWDGLVRITFVRKNKTLSAAFKSSAVQQLLEKNYRIHCSVHNIIIPEDF 242 Query: 271 SIADKIQQILTSTGFSDKRARSMDIDDFIRLLHGFNAEGIHFS 313 SIADKIQQILTSTGFSDKRARSMDIDDFIRLLHGFNAEGIHFS Sbjct: 243 SIADKIQQILTSTGFSDKRARSMDIDDFIRLLHGFNAEGIHFS 285 >2H1R-A nrPDB Length = 299 Score = 337 bits (863), Expect = 5e-93, Method: Composition-based stats. Identities = 131/278 (47%), Positives = 187/278 (67%), Gaps = 2/278 (0%) Query: 35 GQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAEL 94 GQH+LKNP I++ II A ++ +D+VLE+G GTGN+TVKLL AKKV+ ++D R+++E+ Sbjct: 21 GQHLLKNPGILDKIIYAAKIKSSDIVLEIGCGTGNLTVKLLPLAKKVITIDIDSRMISEV 80 Query: 95 HKRVQGTPVASKLQVLVGDVLKTDLPFFDTCVANLPYQISSPFVFKLLLHRPFFRCAILM 154 KR + L+V GD +KT P FD C AN+PY+ISSP +FKL+ HRP F+CA+LM Sbjct: 81 KKRCLYE-GYNNLEVYEGDAIKTVFPKFDVCTANIPYKISSPLIFKLISHRPLFKCAVLM 139 Query: 155 FQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPPKVESSVVRIEPKNP 214 FQ+EFA R++A GD Y RL+IN +L +V + V +++F PPPKV+S +V++ PK Sbjct: 140 FQKEFAERMLANVGDSNYSRLTINVKLFCKVTKVCNVNRSSFNPPPKVDSVIVKLIPKES 199 Query: 215 PPPINFQEWDGLVRITFVRKNKTLSAAFKSSAVQQLLEKNYRIHCSVHNIIIPEDFSIAD 274 NF EWD L+RI F RK KTL A FK +AV +LE NY+ C++ N +P +F Sbjct: 200 SFLTNFDEWDNLLRICFSRKRKTLHAIFKRNAVLNMLEHNYKNWCTL-NKQVPVNFPFKK 258 Query: 275 KIQQILTSTGFSDKRARSMDIDDFIRLLHGFNAEGIHF 312 +L +KR+ ++D +DF++LL FN +GIHF Sbjct: 259 YCLDVLEHLDMCEKRSINLDENDFLKLLLEFNKKGIHF 296 >3TQS-A nrPDB Length = 255 Score = 268 bits (686), Expect = 2e-72, Method: Composition-based stats. Identities = 76/262 (29%), Positives = 120/262 (45%), Gaps = 23/262 (8%) Query: 31 NTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRL 90 GQH L + ++ I+ + TD ++E+GPG G +T LL + + E+D L Sbjct: 4 RKRFGQHFLHDSFVLQKIVSAIHPQKTDTLVEIGPGRGALTDYLLTECDNLALVEIDRDL 63 Query: 91 VAELHKRVQGTPVASKLQVLVGDVLKTDLPFFDT-----CVANLPYQISSPFVFKLLLHR 145 VA L K+ + + D L+ D T V NLPY IS+P +F L Sbjct: 64 VAFLQKKYNQ---QKNITIYQNDALQFDFSSVKTDKPLRVVGNLPYNISTPLLFHLFSQI 120 Query: 146 PFFRCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPPKVESS 205 M Q+E R+ A+ G Y RLS+ Q +L V F PPP+VES+ Sbjct: 121 HCIEDMHFMLQKEVVRRITAEVGSHDYGRLSVMAQYFCDNTYLFTVSPQAFTPPPRVESA 180 Query: 206 VVRIEPKNPPPPI--NFQEWDGLVRITFVRKNKTLSAAFK---SSAVQQLLEKNYRIHCS 260 ++R+ P++ P+ N + +V+ F + KT+ A K + + LLE N ++ Sbjct: 181 IIRLIPRHNFTPVAKNLDQLSHVVKEAFSYRRKTVGNALKKLINPSQWPLLEINPQLR-- 238 Query: 261 VHNIIIPEDFSIAD--KIQQIL 280 P++ ++ D KI IL Sbjct: 239 ------PQELTVEDFVKISNIL 254 >3GRV-A nrPDB Length = 295 Score = 268 bits (685), Expect = 2e-72, Method: Composition-based stats. Identities = 94/268 (35%), Positives = 142/268 (52%), Gaps = 19/268 (7%) Query: 22 LKSAGGLMFN--TGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAK 79 L G MF +GQ L + +N ++ A L DVVLE+G G G +T +L + AK Sbjct: 14 LVPRGSHMFKPKKKLGQCFLIDKNFVNKAVESANLTKDDVVLEIGLGKGILTEELAKNAK 73 Query: 80 KVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVLKTDLPF--FDTCVANLPYQISSPF 137 KV E+D L +K + + + ++++ GD LK DL F+ VANLPYQISSP Sbjct: 74 KVYVIEIDKSLEPYANKLKE---LYNNIEIIWGDALKVDLNKLDFNKVVANLPYQISSPI 130 Query: 138 VFKLLLHRPFFRCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFR 197 FKL+ + F A+LM+Q EFA R+VA G K Y RLS+ Q A V+ + KV + F Sbjct: 131 TFKLI--KRGFDLAVLMYQYEFAKRMVAAAGTKDYGRLSVAVQSRADVEIVAKVPPSAFY 188 Query: 198 PPPKVESSVVRIEPKNPPPPI-NFQEWDGLVRITFVRKNKTLSAA---------FKSSAV 247 P PKV S++V+I+P I N +D +R F +NK++ A + + Sbjct: 189 PKPKVYSAIVKIKPNKGKYHIENENFFDDFLRAIFQHRNKSVRKALIDSSKELNYNKDEM 248 Query: 248 QQLLEKNYRIHCSVHNIIIPEDFSIADK 275 +++LE + + N+I + F ++ K Sbjct: 249 KKILEDFLNTNSEIKNLINEKVFKLSVK 276 >6IFX-A nrPDB Length = 287 Score = 263 bits (672), Expect = 7e-71, Method: Composition-based stats. Identities = 87/299 (29%), Positives = 138/299 (46%), Gaps = 41/299 (13%) Query: 20 RELKSAGGLMFNTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAK 79 +E+ G F +GQ+ L + I+N I+D A + V+E+GPG G +T +L ++AK Sbjct: 12 KEILKKYGFSFKKSLGQNFLIDTNILNRIVDHAEVTEKTGVIEIGPGIGALTEQLAKRAK 71 Query: 80 KVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVLKTDLPF-----FDTC-----VANL 129 KVVA E+D RL+ L + + V+ DVLK D+ F C VANL Sbjct: 72 KVVAFEIDQRLLPILKDTLSP---YENVTVIHQDVLKADVKSVIEEQFQDCDEIMVVANL 128 Query: 130 PYQISSPFVFKLLLHRPFFRCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLM 189 PY +++P + KLL + ++M Q+E A R+ LSI Q +M Sbjct: 129 PYYVTTPIIMKLLEEHLPLKGIVVMLQKEVAERMANTKRS-----LSIAVQFYTEAKTVM 183 Query: 190 KVGKNNFRPPPKVESSVVRIEPKNPPPPI--NFQEWDGLVRITFVRKNKTLSAAFKSSAV 247 V K F P P V+S+V+R+ ++ P N + L++ +F ++ KTL Sbjct: 184 IVPKTVFVPQPNVDSAVIRLILRDGPAVDVENESFFFQLIKASFAQRRKTLL-------- 235 Query: 248 QQLLEKNYRIHCSVHNIIIPEDFSIADKIQQILTSTGFSDK-RARSMDIDDFIRLLHGF 305 + +PE + I+Q+L T K R S+ I++F L +G Sbjct: 236 ------------NNLVNNLPEGKAQKSTIEQVLEETNIDGKRRGESLSIEEFAALSNGL 282 >3FUV-A nrPDB Length = 271 Score = 262 bits (669), Expect = 2e-70, Method: Composition-based stats. Identities = 85/293 (29%), Positives = 130/293 (44%), Gaps = 39/293 (13%) Query: 20 RELKSAGGLMFNTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAK 79 R L GL + GQ+ L + + I++ A T V EVGPG G +T LLE Sbjct: 11 RALLERHGLFADKRFGQNFLVSEAHLRRIVEAARPF-TGPVFEVGPGLGALTRALLEAGA 69 Query: 80 KVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVL---KTDLPFFDTCVANLPYQISSP 136 +V A E D RL L + + G P ++++ D L ++P VANLPY I++P Sbjct: 70 EVTAIEKDLRLRPVLEETLSGLP----VRLVFQDALLYPWEEVPQGSLLVANLPYHIATP 125 Query: 137 FVFKLLLHRPFFRCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNF 196 V +LL F R + + Q+E A R+ A+P Y L++ A + L + F Sbjct: 126 LVTRLLKTGRFARL-VFLVQKEVAERMTARPKTPAYGVLTLRVAHHAVAERLFDLPPGAF 184 Query: 197 RPPPKVESSVVRIEPKNP-PPPINFQEWDGLVRITFVRKNKTLSAAFKSSAVQQLLEKNY 255 PPPKV SS+VR+ P P F+ LV F ++ KTL A ++ + Sbjct: 185 FPPPKVWSSLVRLTPTGALDDPGLFR----LVEAAFGKRRKTLLNALAAAGYPK------ 234 Query: 256 RIHCSVHNIIIPEDFSIADKIQQILTSTGFSDK-RARSMDIDDFIRLLHGFNA 307 ++++ L + G + RA +D++ F RL G Sbjct: 235 ------------------ARVEEALRALGLPPRVRAEELDLEAFRRLREGLEG 269 >3FYD-A nrPDB Length = 263 Score = 257 bits (657), Expect = 4e-69, Method: Composition-based stats. Identities = 89/252 (35%), Positives = 136/252 (53%), Gaps = 17/252 (6%) Query: 36 QHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELH 95 Q L + +N ++ A L DVVLE+G G G +T +L + AKKV E+D L + Sbjct: 1 QCFLIDKNFVNKAVESANLTKDDVVLEIGLGKGILTEELAKNAKKVYVIEIDKSLEPYAN 60 Query: 96 KRVQGTPVASKLQVLVGDVLKTDLPF--FDTCVANLPYQISSPFVFKLLLHRPFFRCAIL 153 K + + + ++++ GD LK DL F+ VANLPYQISSP FKL+ + F A+L Sbjct: 61 KLKE---LYNNIEIIWGDALKVDLNKLDFNKVVANLPYQISSPITFKLI--KRGFDLAVL 115 Query: 154 MFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPPKVESSVVRIEPKN 213 M+Q EFA R+VA G K Y RLS+ Q A V+ + KV + F P PKV S++V+I+P Sbjct: 116 MYQYEFAKRMVAAAGTKDYGRLSVAVQSRADVEIVAKVPPSAFYPKPKVYSAIVKIKPNK 175 Query: 214 PPPPI-NFQEWDGLVRITFVRKNKTLSAA---------FKSSAVQQLLEKNYRIHCSVHN 263 I N +D +R F +NK++ A + ++++LE + + N Sbjct: 176 GKYHIENENFFDDFLRAIFQHRNKSVRKALIDSSKELNYNKDEMKKILEDFLNTNSEIKN 235 Query: 264 IIIPEDFSIADK 275 +I + F ++ K Sbjct: 236 LINEKVFKLSVK 247 >3UZU-A nrPDB Length = 279 Score = 251 bits (642), Expect = 2e-67, Method: Composition-based stats. Identities = 68/230 (29%), Positives = 105/230 (45%), Gaps = 19/230 (8%) Query: 27 GLMFNTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMT----VKLLEKAKKVV 82 G GQ+ L + +I++I+ + ++E+GPG G +T +L + Sbjct: 13 GHFARKRFGQNFLVDHGVIDAIVAAIRPERGERMVEIGPGLGALTGPVIARLATPGSPLH 72 Query: 83 ACELDPRLVAELHKRVQGTPVASKLQVLVGDVLKTDLPFFDT--------CVANLPYQIS 134 A ELD L+ L +R L++ GD L D + NLPY IS Sbjct: 73 AVELDRDLIGRLEQRF-----GELLELHAGDALTFDFGSIARPGDEPSLRIIGNLPYNIS 127 Query: 135 SPFVFKLLLHRPFFRCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKN 194 SP +F L+ P M Q E R+VA+PG K + RLS+ Q +D L+ V Sbjct: 128 SPLLFHLMSFAPVVIDQHFMLQNEVVERMVAEPGTKAFSRLSVMLQYRYVMDKLIDVPPE 187 Query: 195 NFRPPPKVESSVVRIEPKNPP--PPINFQEWDGLVRITFVRKNKTLSAAF 242 +F+PPPKV+S++VR+ P P P ++ +V F ++ K L Sbjct: 188 SFQPPPKVDSAIVRMIPHAPHELPAVDPAVLGEVVTAAFSQRRKMLRNTL 237 >4JXJ-A nrPDB Length = 276 Score = 250 bits (637), Expect = 7e-67, Method: Composition-based stats. Identities = 75/248 (30%), Positives = 121/248 (48%), Gaps = 13/248 (5%) Query: 32 TGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKV-VACELDPRL 90 GQ+ + + + + I+ + L VLE+GPGTG +T +L K K+ E D R Sbjct: 26 KKHGQNFIFDGSLCDKIVRASGLEENSNVLEIGPGTGGLTRSILHKNPKLLTVIETDERC 85 Query: 91 VAELHKRVQGTPVASKLQVLVGDVLKTDLPFFDT----CVANLPYQISSPFVFKLLLHRP 146 + L++ Q P L ++ D LK L +T ++NLPY I + V + L Sbjct: 86 IPLLNEIKQYHP---NLNIIKQDALKLKLSDLNTNKITIISNLPYHIGTELVIRWLKESS 142 Query: 147 FFRCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPPKVESSV 206 LM Q+E R+ AKP K Y RLS+ L+A V+ V F PPPKV S++ Sbjct: 143 LVASMTLMLQKEVVERICAKPSTKAYGRLSVICSLIATVEKCFDVAPTAFYPPPKVYSAI 202 Query: 207 VRIEP-KNPPPPINFQEWDGLVRITFVRKNKTLSAAFKSSA--VQQLLEK-NYRIHCSVH 262 V++ P +N P + + + ++ F + K + ++ K+ A + +LL K N +C Sbjct: 203 VKLTPLENIPNSDLISKVELITKMAFAGRRKMIKSSLKNLAPNISELLAKLNISDNCRAE 262 Query: 263 NIIIPEDF 270 N+ P D+ Sbjct: 263 NL-TPNDY 269 >1QYR-A nrPDB Length = 252 Score = 247 bits (630), Expect = 5e-66, Method: Composition-based stats. Identities = 63/219 (28%), Positives = 102/219 (46%), Gaps = 14/219 (6%) Query: 36 QHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELH 95 Q+ L + +I+SI+ + ++E+GPG +T + E+ ++ ELD L A Sbjct: 1 QNFLNDQFVIDSIVSAINPQKGQAMVEIGPGLAALTEPVGERLDQLTVIELDRDLAA--- 57 Query: 96 KRVQGTP-VASKLQVLVGDVLKTDLPFFD-------TCVANLPYQISSPFVFKLLLHRPF 147 R+Q P + KL + D + + NLPY IS+P +F L + Sbjct: 58 -RLQTHPFLGPKLTIYQQDAMTFNFGELAEKMGQPLRVFGNLPYNISTPLMFHLFSYTDA 116 Query: 148 FRCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPPKVESSVV 207 M Q+E RLVA P K Y RLS+ Q V +++V + F PPPKV+S+VV Sbjct: 117 IADMHFMLQKEVVNRLVAGPNSKAYGRLSVMAQYYCNVIPVLEVPPSAFTPPPKVDSAVV 176 Query: 208 RIEPKN--PPPPINFQEWDGLVRITFVRKNKTLSAAFKS 244 R+ P P P + + + F ++ KT+ + + Sbjct: 177 RLVPHATMPHPVKDVRVLSRITTEAFNQRRKTIRNSLGN 215 >6IFV-A nrPDB Length = 215 Score = 236 bits (601), Expect = 1e-62, Method: Composition-based stats. Identities = 72/207 (34%), Positives = 108/207 (52%), Gaps = 13/207 (6%) Query: 20 RELKSAGGLMFNTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAK 79 +E+ G F +GQ+ L + I+N I+D A + V+E+GPG G +T +L ++AK Sbjct: 12 KEILKKYGFSFKKSLGQNFLIDTNILNRIVDHAEVTEKTGVIEIGPGIGALTEQLAKRAK 71 Query: 80 KVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVLKTDLPF-----FDTC-----VANL 129 KVVA E+D RL+ L + + V+ DVLK D+ F C VANL Sbjct: 72 KVVAFEIDQRLLPILKDTLSP---YENVTVIHQDVLKADVKSVIEEQFQDCDEIMVVANL 128 Query: 130 PYQISSPFVFKLLLHRPFFRCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLM 189 PY +++P + KLL + ++M Q+E A R+ A P K Y LSI Q +M Sbjct: 129 PYYVTTPIIMKLLEEHLPLKGIVVMLQKEVAERMAADPSSKEYGSLSIAVQFYTEAKTVM 188 Query: 190 KVGKNNFRPPPKVESSVVRIEPKNPPP 216 V K F P P V+S+V+R+ ++ P Sbjct: 189 IVPKTVFVPQPNVDSAVIRLILRDGPA 215 >4GC9-A nrPDB Length = 345 Score = 219 bits (558), Expect = 1e-57, Method: Composition-based stats. Identities = 73/248 (29%), Positives = 106/248 (42%), Gaps = 27/248 (10%) Query: 20 RELKSAGGLMFNTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLE-KA 78 RE+ GL + Q+ L + + + I+ KA V EVGPG G +T +L Sbjct: 19 REIIKLFGLRAVKQLSQNFLLDLRLTDKIVRKAGSLADVYVYEVGPGPGGITRSILNANV 78 Query: 79 KKVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVL---------------KTDLPFFD 123 +++ E D R + L P KL+++ GDVL D P Sbjct: 79 AELLVVEKDTRFIPGLQMLSDAAP--GKLRIVHGDVLTYKIEKAFPGNIRRQWEDDPPNV 136 Query: 124 TCVANLPYQISSPFVFKLLLH-----RPFFRC---AILMFQREFALRLVAKPGDKLYCRL 175 + NLP+ +S+P + K L + PF L FQ+E A RLVA G K + RL Sbjct: 137 HIIGNLPFSVSTPLIIKWLENISLKDGPFVYGRTKMTLTFQKEVAERLVATTGSKQHSRL 196 Query: 176 SINTQLLARVDHLMKVGKNNFRPPPKVESSVVRIEPK-NPPPPINFQEWDGLVRITFVRK 234 SI Q L V+HL + F P PKV+ VV + P P F+ + +V+ F + Sbjct: 197 SIMAQYLCNVEHLFTIPGKAFVPKPKVDVGVVHLTPLIEPKIKQPFKLVEKVVQNAFQFR 256 Query: 235 NKTLSAAF 242 K Sbjct: 257 RKYCHRGL 264 >3R9X-B nrPDB Length = 248 Score = 189 bits (480), Expect = 1e-48, Method: Composition-based stats. Identities = 62/254 (24%), Positives = 110/254 (43%), Gaps = 15/254 (5%) Query: 29 MFNTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEK-AKKVVACELD 87 GQH+L + ++ I ++ + + V+EVG GTGN+T LL+ KK+ ELD Sbjct: 3 RLKKSFGQHLLVSEGVLKKIAEELNIEEGNTVVEVGGGTGNLTKVLLQHPLKKLYVIELD 62 Query: 88 PRLVAELHKRVQGTPVASKLQVLVGDVLKTDL---PFFDTCVANLPYQISSPFVFKLLLH 144 +V L + +L+V+ D K V NLPY ++S + + + Sbjct: 63 REMVENLK-----SIGDERLEVINEDASKFPFCSLGKELKVVGNLPYNVASLIIENTVYN 117 Query: 145 RPFFRCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPPKVES 204 + A+ M Q+E A +L G K LS+ + V+++M V F PPPKV+S Sbjct: 118 KDCVPLAVFMVQKEVAEKL---QGKKDTGWLSVFVRTFYDVNYVMTVPPRFFVPPPKVQS 174 Query: 205 SVVRIEPKNPPPPINFQEWDGLVRITFVRKNKTLSAAFKSSAVQQLLEKNYRIHCSVHNI 264 +V+++ P + + + + F + K L ++ E V + Sbjct: 175 AVIKLVKNEKFPVKDLKNYKKFLTKIFQNRRKVLRKKIPEELLK---EAGINPDARVEQL 231 Query: 265 IIPEDFSIADKIQQ 278 + + F + I+ Sbjct: 232 SLEDFFKLYRLIED 245 >1YUB-A nrPDB Length = 245 Score = 189 bits (479), Expect = 2e-48, Method: Composition-based stats. Identities = 52/232 (22%), Positives = 103/232 (44%), Gaps = 17/232 (7%) Query: 31 NTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRL 90 N Q+ L + ++N II + L+ TD V E+G G G++T KL + +K+V + ELD L Sbjct: 4 NIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLTTKLAKISKQVTSIELDSHL 63 Query: 91 VAELHKRVQGTPVASKLQVLVGDVLKTDLPFFD--TCVANLPYQISSPFVFKLLLHRPFF 148 ++++ + +++ ++ D+L+ P V N+PY +S+ + K++ Sbjct: 64 FNLSSEKLK---LNTRVTLIHQDILQFQFPNKQRYKIVGNIPYHLSTQIIKKVVFESR-A 119 Query: 149 RCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPPKVESSVVR 208 L+ + F R + ++ L + + L+K+ F P PKV S +++ Sbjct: 120 SDIYLIVEEGFYKRTL-----DIHRTLGLLLHTQVSIQQLLKLPAECFHPKPKVNSVLIK 174 Query: 209 IEPKNPPPPINFQEWDGLVRITFVRK--NKTLSAAFKSSAVQQLLEKNYRIH 258 + P + W + FV K N+ F + Q ++ + Sbjct: 175 LTRHTTDVPDKY--WK--LYTYFVSKWVNREYRQLFTKNQFHQAMKHAKVNN 222 >1QAM-A nrPDB Length = 244 Score = 181 bits (458), Expect = 5e-46, Method: Composition-based stats. Identities = 56/228 (24%), Positives = 96/228 (42%), Gaps = 19/228 (8%) Query: 31 NTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRL 90 N Q+ + + I+ I+ L D + E+G G G+ T++L+++ V A E+D +L Sbjct: 5 NIKHSQNFITSKHNIDKIMTNIRLNEHDNIFEIGSGKGHFTLELVQRCNFVTAIEIDHKL 64 Query: 91 VAELHKRVQGTPVASKLQVLVGDVLKTDLPFFD--TCVANLPYQISSPFVFKLLLHRPFF 148 ++ QVL D+L+ P N+PY IS+ + K++ Sbjct: 65 CKTTENKLVDH---DNFQVLNKDILQFKFPKNQSYKIFGNIPYNISTDIIRKIVF-DSIA 120 Query: 149 RCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVD--HLMKVGKNNFRPPPKVESSV 206 L+ + FA RL+ + S+ L+A VD L V + F P PKV SS+ Sbjct: 121 DEIYLIVEYGFAKRLL-------NTKRSLALFLMAEVDISILSMVPREYFHPKPKVNSSL 173 Query: 207 VRIEPKNPP-PPINFQEWDGLVRITFVRKNKTLSAAFKSSAVQQLLEK 253 +R+ K + Q+++ V NK F + L+ Sbjct: 174 IRLNRKKSRISHKDKQKYNYFVMKWV---NKEYKKIFTKNQFNNSLKH 218 >6ERO-A nrPDB Length = 313 Score = 93.6 bits (231), Expect = 1e-19, Method: Composition-based stats. Identities = 59/265 (22%), Positives = 99/265 (37%), Gaps = 58/265 (21%) Query: 55 RPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGDV 114 RP ++LE PG G +T LLE KVVA E D + L G + KL+V+ D Sbjct: 34 RPPHLLLECNPGPGILTQALLEAGAKVVALESDKTFIPHLE--SLGKNLDGKLRVIHCDF 91 Query: 115 LKTDLPFFDTC----------VANL-----PYQISSPF--------------VFKLLLHR 145 K D NL P+ P ++KL Sbjct: 92 FKLDPRSGGVIKPPAMSSRGLFKNLGIEAVPWTADIPLKVVGMFPSRGEKRALWKLAYDL 151 Query: 146 PFFRCAI---------LMFQREFALRLVAKPGDKL-YCRLSINTQLLARVDHLMKVGKNN 195 + ++EF +L+A PG+ Y LS+ QL + L ++ Sbjct: 152 YSCTSIYKFGRIEVNMFIGEKEF-QKLMADPGNPDLYHVLSVIWQLACEIKVLHMEPGSS 210 Query: 196 FRPPPKVESSVVRIEPK-----NPPPPINFQEWDGLVRITFVRKNKTLSAAFKS----SA 246 K+ ++++ P+ P+N+ + L++ F R++ T+ +S A Sbjct: 211 ----GKLY--LIQMIPRQNLFTKNLTPMNYNIFFHLLKHCFGRRSATVIDHLRSLTPLDA 264 Query: 247 VQQLLEKNYRIHCSVHNIIIPEDFS 271 L++ + V N+ P+DF Sbjct: 265 RDILMQIGKQEDEKVVNM-HPQDFK 288 >6ERQ-F nrPDB Length = 377 Score = 89.4 bits (220), Expect = 2e-18, Method: Composition-based stats. Identities = 61/284 (21%), Positives = 101/284 (35%), Gaps = 73/284 (25%) Query: 55 RPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGDV 114 RP ++LE PG G +T LLE KVVA E D + L G + KL+V+ D Sbjct: 75 RPPHLLLECNPGPGILTQALLEAGAKVVALESDKTFIPHLE--SLGKNLDGKLRVIHCDF 132 Query: 115 LKTDLPFFDTC----------VANL-----PYQISSPF--------------VFKLLLHR 145 K D NL P+ P ++KL Sbjct: 133 FKLDPRSGGVIKPPAMSSRGLFKNLGIEAVPWTADIPLKVVGMFPSRGEKRALWKLAYDL 192 Query: 146 PFFRCAI---------LMFQREFALRLVAKPGDKL-YCRLSINTQLLARVDHLMKVGKNN 195 + ++EF +L+A PG+ Y LS+ QL + L ++ Sbjct: 193 YSCTSIYKFGRIEVNMFIGEKEF-QKLMADPGNPDLYHVLSVIWQLACEIKVLHMEPWSS 251 Query: 196 F----------RPP---------PKVESSVVRIEPK-----NPPPPINFQEWDGLVRITF 231 F P K+ ++++ P+ P+N+ + L++ F Sbjct: 252 FDIYTRKGPLENPKRRELLDQLQQKLY--LIQMIPRQNLFTKNLTPMNYNIFFHLLKHCF 309 Query: 232 VRKNKTLSAAFKS----SAVQQLLEKNYRIHCSVHNIIIPEDFS 271 R++ T+ +S A L++ + V N+ P+DF Sbjct: 310 GRRSATVIDHLRSLTPLDARDILMQIGKQEDEKVVNM-HPQDFK 352 >1L3B-A nrPDB Length = 192 Score = 53.6 bits (127), Expect = 1e-07, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 35/67 (52%) Query: 48 IIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKL 107 I+ A DV ++VG GTG +T++L + ++V A + +P ++ +Q + + Sbjct: 25 IMCLAEPGKNDVAVDVGCGTGGVTLELAGRVRRVYAIDRNPEAISTTEMNLQRHGLGDNV 84 Query: 108 QVLVGDV 114 ++ GD Sbjct: 85 TLMEGDA 91 >3HNR-A nrPDB Length = 220 Score = 48.6 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 23/103 (22%), Positives = 42/103 (40%), Gaps = 10/103 (9%) Query: 31 NTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRL 90 + + I+ +++K+ VLE G GTGN+T KLL + V E + Sbjct: 24 DIQYKEVFAHYEDILEDVVNKSF----GNVLEFGVGTGNLTNKLLLAGRTVYGIEPSREM 79 Query: 91 VAELHKRVQGTPVASKLQVLVGDVLKTDLP-FFDTCVANLPYQ 132 +++ + + GD L ++P DT V+ + Sbjct: 80 RMIAKEKLP-----KEFSITEGDFLSFEVPTSIDTIVSTYAFH 117 >5BXY-A nrPDB Length = 158 Score = 48.2 bits (113), Expect = 4e-06, Method: Composition-based stats. Identities = 29/135 (21%), Positives = 56/135 (41%), Gaps = 4/135 (2%) Query: 44 IINSIIDKAALRPTDVVLEVGPGTGNMTVKLL-EKAKKVVACELDPRLVAELHKRVQGTP 102 +++ +++ A + TDV+ ++G G G + ++ + V E+DP LV + K + Sbjct: 12 VVDRMLELADVDETDVLYDLGSGDGRIVIRAARTHGARGVGIEIDPDLVKKARKNAKEAG 71 Query: 103 VASKLQVLVGDVLKTDLPFFDTCVANLPYQISS---PFVFKLLLHRPFFRCAILMFQREF 159 VA ++ GD+ + D+ L ++ P +F+ L R Sbjct: 72 VADLVEFRQGDLFEADISEATVVTLYLLPSVNQKLRPILFEQLSPGTPVVSHDFDMGRWA 131 Query: 160 ALRLVAKPGDKLYCR 174 R V GD +Y Sbjct: 132 PDRTVDLEGDTVYRW 146 >1VBF-A nrPDB Length = 231 Score = 47.8 bits (112), Expect = 6e-06, Method: Composition-based stats. Identities = 17/66 (25%), Positives = 34/66 (51%), Gaps = 3/66 (4%) Query: 48 IIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKL 107 ++D+ L VLE+G G G T + E KVV+ E++ ++ K + + + Sbjct: 62 MLDELDLHKGQKVLEIGTGIGYYTALIAEIVDKVVSVEINEKMYNYASKLLS---YYNNI 118 Query: 108 QVLVGD 113 ++++GD Sbjct: 119 KLILGD 124 >4IV8-A nrPDB Length = 284 Score = 46.3 bits (108), Expect = 2e-05, Method: Composition-based stats. Identities = 28/121 (23%), Positives = 48/121 (39%), Gaps = 17/121 (14%) Query: 21 ELKSAGGLMFNTGIGQHILKNPLII--NSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKA 78 E A +F G+ + + I+ I+ L P VL++G G G + EK Sbjct: 39 EGIKAYEFIF----GEDYISSGGIVATTKILSDIYLEPNSKVLDIGSGLGGGCKYINEKY 94 Query: 79 K-KVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVLKTDLPFF-------DTCVANLP 130 V ++ +++A R + SK++ D+LK D P + +LP Sbjct: 95 DAHVYGVDICEKMIAIAKLRNKDK---SKVEFEAMDILKKDFPECTFDMIYSRDAILHLP 151 Query: 131 Y 131 Y Sbjct: 152 Y 152 >2YXD-A nrPDB Length = 183 Score = 46.3 bits (108), Expect = 2e-05, Method: Composition-based stats. Identities = 18/79 (22%), Positives = 33/79 (41%), Gaps = 16/79 (20%) Query: 49 IDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKLQ 108 I K L DVV++VG G+G MTV++ ++ K V A + + ++ Sbjct: 28 IGKLNLNKDDVVVDVGCGSGGMTVEIAKRCKFVYAID----------------YLDGAIE 71 Query: 109 VLVGDVLKTDLPFFDTCVA 127 V ++ K ++ Sbjct: 72 VTKQNLAKFNIKNCQIIKG 90 >3DMF-A nrPDB Length = 381 Score = 44.3 bits (103), Expect = 6e-05, Method: Composition-based stats. Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 6/82 (7%) Query: 60 VLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGD---VLK 116 VL++G G G +T+ L +VV E D V L K ++ + K Q L D L Sbjct: 237 VLDLGAGYGALTLPLARMGAEVVGVEDDLASVLSLQKGLEANAL--KAQALHSDVDEALT 294 Query: 117 TDLPFFDTCVANLPYQISSPFV 138 + FD V N P+ + + Sbjct: 295 EE-ARFDIIVTNPPFHVGGAVI 315 >4MWZ-A nrPDB Length = 267 Score = 44.0 bits (102), Expect = 8e-05, Method: Composition-based stats. Identities = 25/104 (24%), Positives = 40/104 (38%), Gaps = 10/104 (9%) Query: 21 ELKSAGGLMFNTGIGQHILKNPLII--NSIIDKAALRPTDVVLEVGPGTGNMTVKLLEK- 77 E A +F G+ + + II I+ L VL++G G G + EK Sbjct: 22 EGIKAYEFIF----GEDYISSGGIIATTKILSDIQLDANSKVLDIGSGLGGGCKYINEKY 77 Query: 78 AKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVLKTDLPF 121 V ++ ++V R Q K++ D+LK D P Sbjct: 78 GAHVHGVDICEKMVTIAKLRNQDKA---KIEFEAKDILKKDFPE 118 >4FGZ-A nrPDB Length = 266 Score = 44.0 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 18/93 (19%), Positives = 38/93 (40%), Gaps = 6/93 (6%) Query: 34 IGQHILKNPLI--INSIIDKAALRPTDVVLEVGPGTGNMTVKLLEK-AKKVVACELDPRL 90 G++ + + + I+ L VL++G G G + + EK ++ + Sbjct: 31 FGENYISSGGLEATKKILSDIELNENSKVLDIGSGLGGGCMYINEKYGAHTHGIDICSNI 90 Query: 91 VAELHKRVQGTPVASKLQVLVGDVLKTDLPFFD 123 V ++RV G +K+ D+L + P + Sbjct: 91 VNMANERVSG---NNKIIFEANDILTKEFPENN 120 >3EGE-A nrPDB Length = 261 Score = 43.6 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 16/54 (29%), Positives = 26/54 (48%) Query: 32 TGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACE 85 Q + + I+N+II+ L V+ ++G GTG +V L + V A E Sbjct: 10 KQYSQTRVPDIRIVNAIINLLNLPKGSVIADIGAGTGGYSVALANQGLFVYAVE 63 >4L7V-A nrPDB Length = 225 Score = 42.8 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 22/82 (26%), Positives = 35/82 (42%), Gaps = 2/82 (2%) Query: 32 TGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLV 91 G GQ + P I+ + + AL P VLE+G G+G T L + V E L Sbjct: 69 IGQGQT-ISQPYIVAKMTELLALTPETKVLEIGTGSGYQTAVLAKLVNHVFTVERIKTLQ 127 Query: 92 AELHKRVQGTPVASKLQVLVGD 113 + +R++ + + GD Sbjct: 128 WDAKRRLKQLDIY-NVSTKHGD 148 >3LBF-A nrPDB Length = 210 Score = 42.0 bits (97), Expect = 4e-04, Method: Composition-based stats. Identities = 26/113 (23%), Positives = 46/113 (40%), Gaps = 5/113 (4%) Query: 32 TGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLV 91 G GQ + P ++ + + L P VLE+G G+G T L + V + E L Sbjct: 54 IGQGQT-ISQPYMVARMTELLELTPQSRVLEIGTGSGYQTAILAHLVQHVCSVERIKGLQ 112 Query: 92 AELHKRVQGTPVASKLQVLVGD---VLKTDLPFFDTCVANLPYQISSPFVFKL 141 + +R++ + + GD + PF V P +I + + +L Sbjct: 113 WQARRRLKNLDLH-NVSTRHGDGWQGWQARAPFDAIIVTAAPPEIPTALMTQL 164 >3LGA-A nrPDB Length = 253 Score = 41.6 bits (96), Expect = 4e-04, Method: Composition-based stats. Identities = 17/87 (19%), Positives = 38/87 (43%), Gaps = 4/87 (4%) Query: 48 IIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKK---VVACELDPRLVAELHKRVQGTPVA 104 I+ A + P D ++E G G+G +T+ L VV+ E+ + ++ Sbjct: 85 IVAYAGISPGDFIVEAGVGSGALTLFLANIVGPEGRVVSYEIREDFAKLAWENIKWAGFD 144 Query: 105 SKLQVLVGDVLK-TDLPFFDTCVANLP 130 ++ + + D+ + + D + +LP Sbjct: 145 DRVTIKLKDIYEGIEEENVDHVILDLP 171 >2YVL-A nrPDB Length = 248 Score = 41.6 bits (96), Expect = 5e-04, Method: Composition-based stats. Identities = 17/74 (22%), Positives = 27/74 (36%) Query: 48 IIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKL 107 I K L VLE G G+G + L E A +V E K ++ + + Sbjct: 83 IALKLNLNKEKRVLEFGTGSGALLAVLSEVAGEVWTFEAVEEFYKTAQKNLKKFNLGKNV 142 Query: 108 QVLVGDVLKTDLPF 121 + D ++P Sbjct: 143 KFFNVDFKDAEVPE 156 >5WP4-A nrPDB Length = 491 Score = 40.5 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 25/110 (22%), Positives = 44/110 (40%), Gaps = 3/110 (2%) Query: 21 ELKSAGGLMFNTGIGQHILKNPLI--INSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKA 78 + KS+G L + GQ + + ++K L+P VL+VG G G + EK Sbjct: 245 QYKSSGILRYERVFGQGFVSTGGLETTKEFVEKMNLKPGQKVLDVGCGIGGGDFYMAEKF 304 Query: 79 K-KVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVLKTDLPFFDTCVA 127 VV +L +++ +R G + + +V FD + Sbjct: 305 DVHVVGIDLSVNMISFALERAIGLSCSVEFEVADCTTKHYPDNSFDVIYS 354 Score = 35.5 bits (80), Expect = 0.029, Method: Composition-based stats. Identities = 19/87 (21%), Positives = 34/87 (39%), Gaps = 9/87 (10%) Query: 47 SIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACE-LDPRLVAELHKRVQGTPVAS 105 ++ VLE+G G G T +L +KA +++A + +D + K Sbjct: 44 EVLSLLPPYEGKSVLELGAGIGRFTGELAQKAGELIALDFID----NVIKKNESINGHYK 99 Query: 106 KLQVLVGDV----LKTDLPFFDTCVAN 128 ++ + DV LK D +N Sbjct: 100 NVKFMCADVTSPDLKITDGSLDLIFSN 126 Score = 30.9 bits (68), Expect = 0.75, Method: Composition-based stats. Identities = 13/61 (21%), Positives = 25/61 (40%) Query: 110 LVGDVLKTDLPFFDTCVANLPYQISSPFVFKLLLHRPFFRCAILMFQREFALRLVAKPGD 169 + V + F + N+ Y+ S ++ + + F L +EF ++ KPG Sbjct: 225 IWQKVSSENDRGFQRFLDNVQYKSSGILRYERVFGQGFVSTGGLETTKEFVEKMNLKPGQ 284 Query: 170 K 170 K Sbjct: 285 K 285 >2GPY-A nrPDB Length = 233 Score = 39.7 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 19/81 (23%), Positives = 41/81 (50%), Gaps = 2/81 (2%) Query: 39 LKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKK--VVACELDPRLVAELHK 96 + + L + S++ + +LE+G G +++ + + +V+ E D R E HK Sbjct: 37 IMDLLGMESLLHLLKMAAPARILEIGTAIGYSAIRMAQALPEATIVSIERDERRYEEAHK 96 Query: 97 RVQGTPVASKLQVLVGDVLKT 117 V+ + S++++L GD L+ Sbjct: 97 HVKALGLESRIELLFGDALQL 117 >1G6Q-1 nrPDB Length = 328 Score = 39.7 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 19/85 (22%), Positives = 38/85 (44%), Gaps = 4/85 (4%) Query: 46 NSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELD-PRLVAELHKRVQGTPVA 104 N+II L +VL+VG GTG +++ + K +D ++ + V+ + Sbjct: 28 NAIIQNKDLFKDKIVLDVGCGTGILSMFAAKHGAK-HVIGVDMSSIIEMAKELVELNGFS 86 Query: 105 SKLQVLVG--DVLKTDLPFFDTCVA 127 K+ +L G + + P D ++ Sbjct: 87 DKITLLRGKLEDVHLPFPKVDIIIS 111 >3CCF-A nrPDB Length = 279 Score = 39.7 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 28/172 (16%), Positives = 55/172 (31%), Gaps = 27/172 (15%) Query: 28 LMFNTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELD 87 F G+ +L +P + +L++G GTG +T K+ + +V+ + Sbjct: 39 HSFVWQYGEDLL----------QLLNPQPGEFILDLGCGTGQLTEKIAQSGAEVLGTDNA 88 Query: 88 PRLVAELHKRVQGTPVASKLQVLVGDVLKTDL-PFFDTCVANLPYQISSPFVFKLLLHRP 146 ++ + + L V D + D +N + + P Sbjct: 89 ATMIEKARQN------YPHLHFDVADARNFRVDKPLDAVFSN--------AMLHWVKE-P 133 Query: 147 FFRCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRP 198 A + + R VA+ G K + I L ++ L P Sbjct: 134 EAAIASIHQALKSGGRFVAEFGGKGNIKY-ILEALYNALETLGIHNPQALNP 184 >4O29-A nrPDB Length = 208 Score = 39.7 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 21/112 (18%), Positives = 43/112 (38%), Gaps = 5/112 (4%) Query: 39 LKNPLIINSIIDKAALRPTDVVLEVGPGTG---NMTVKLLEKAKKVVACELDPRLVAELH 95 + P ++ + + RP +LEVG G+G + + +EK ++ E+ L Sbjct: 58 ISAPHMVAMMCELIEPRPGMKILEVGTGSGYHAAVCAEAIEKKGRIYTIEIVKELAVFAA 117 Query: 96 KRVQGTPVASKLQVLVGDVLK--TDLPFFDTCVANLPYQISSPFVFKLLLHR 145 + ++ ++V GD K FD + + P + + L Sbjct: 118 QNLERLGYWGVVEVYHGDGKKGLEKHAPFDAIIVTAAADVIPPALIRQLKDG 169 >3NTV-A nrPDB Length = 232 Score = 39.3 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 10/79 (12%), Positives = 33/79 (41%), Gaps = 2/79 (2%) Query: 39 LKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKK--VVACELDPRLVAELHK 96 + + L ++ I + +LE+G G +++ + V E + ++ + Sbjct: 54 IVDRLTLDLIKQLIRMNNVKNILEIGTAIGYSSMQFASISDDIHVTTIERNETMIQYAKQ 113 Query: 97 RVQGTPVASKLQVLVGDVL 115 + ++++++ G+ L Sbjct: 114 NLATYHFENQVRIIEGNAL 132 >5EQJ-B nrPDB Length = 383 Score = 39.3 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 12/73 (16%), Positives = 26/73 (35%), Gaps = 1/73 (1%) Query: 48 IIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDP-RLVAELHKRVQGTPVASK 106 I+ + P V+E G G+G+ + + + E R L + + + Sbjct: 102 IMQRLNCSPHSRVIEAGTGSGSFSHAFARSVGHLFSFEFHHIRYEQALEEFKEHGLIDDN 161 Query: 107 LQVLVGDVLKTDL 119 + + DV + Sbjct: 162 VTITHRDVCQGGF 174 >4M36-A nrPDB Length = 343 Score = 38.6 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 31/64 (48%), Gaps = 1/64 (1%) Query: 49 IDKAALRPTDVVLEVGPGTGNMTVKLLEKAKK-VVACELDPRLVAELHKRVQGTPVASKL 107 + K + P VLE+G G+G +++ + K VVA E L + ++ + ++ Sbjct: 53 VLKKHVTPETGVLEIGAGSGLLSLMAAKLGAKWVVAVEGSEELAKLARENIRANNMEHQV 112 Query: 108 QVLV 111 +VL Sbjct: 113 KVLH 116 >5EKU-A nrPDB Length = 390 Score = 38.2 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 31/64 (48%), Gaps = 1/64 (1%) Query: 49 IDKAALRPTDVVLEVGPGTGNMTVKLLEKAKK-VVACELDPRLVAELHKRVQGTPVASKL 107 + K + P VLE+G G+G +++ + K VVA E L + ++ + ++ Sbjct: 88 VLKKHVTPETGVLEIGAGSGLLSLMAAKLGAKWVVAVEGSEELAKLARENIRANNMEHQV 147 Query: 108 QVLV 111 +VL Sbjct: 148 KVLH 151 >3DLC-A nrPDB Length = 219 Score = 38.2 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 37/74 (50%), Gaps = 2/74 (2%) Query: 42 PLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKK-VVACELDPRLVAELHKRVQG 100 P+I +II++ + +++G G G +++ L +++ + A + + K + Sbjct: 30 PIIAENIINRFGITAG-TCIDIGSGPGALSIALAKQSDFSIRALDFSKHMNEIALKNIAD 88 Query: 101 TPVASKLQVLVGDV 114 + ++Q++ GDV Sbjct: 89 ANLNDRIQIVQGDV 102 >1YB2-A nrPDB Length = 275 Score = 38.2 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 20/96 (20%), Positives = 40/96 (41%), Gaps = 4/96 (4%) Query: 39 LKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAK---KVVACELDPRLVAELH 95 + + + + II + LRP +LEVG G+GNM+ +L + E D + + Sbjct: 93 IISEIDASYIIMRCGLRPGMDILEVGVGSGNMSSYILYALNGKGTLTVVERDEDNLKKAM 152 Query: 96 KRVQGTPVASKLQVLVGDVLKT-DLPFFDTCVANLP 130 + ++ D+ +D +A++P Sbjct: 153 DNLSEFYDIGNVRTSRSDIADFISDQMYDAVIADIP 188 >3OFK-A nrPDB Length = 216 Score = 38.2 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 18/75 (24%), Positives = 29/75 (38%), Gaps = 5/75 (6%) Query: 61 LEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVLKTDLP 120 LE+G G T KL K++ ++ PR + Q T S + D+L+ Sbjct: 56 LEIGCAAGAFTEKLAPHCKRLTVIDVMPRAIGRA---CQRTKRWSHISWAATDILQFSTA 112 Query: 121 FFDT--CVANLPYQI 133 VA + Y + Sbjct: 113 ELFDLIVVAEVLYYL 127 >1UWV-A nrPDB Length = 433 Score = 38.2 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 19/82 (23%), Positives = 37/82 (45%), Gaps = 2/82 (2%) Query: 40 KNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQ 99 N ++ ++ ++P D VL++ G GN T+ L +A VV E P LV + + + Sbjct: 270 VNQKMVARALEWLDVQPEDRVLDLFCGMGNFTLPLATQAASVVGVEGVPALVEKGQQNAR 329 Query: 100 GTPVASKLQVLVGDVLKTDLPF 121 + + + L+ D+ Sbjct: 330 LNGLQ-NVTFYHEN-LEEDVTK 349 >5WP5-A nrPDB Length = 491 Score = 38.2 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 31/140 (22%), Positives = 51/140 (36%), Gaps = 26/140 (18%) Query: 47 SIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASK 106 ++ VLE+G G G T +L +KA +V+A + + + + K Sbjct: 44 EVLSLIPPYEGKSVLELGAGIGRFTGELAQKAGEVIALDF---IESAIQKNESVNGHYKN 100 Query: 107 LQVLVGDV----LKTDLPFFDTCVANLPYQISSPFVFKLLLHRPFFRCAILMFQREFALR 162 ++ + DV LK D +N LL + LM A R Sbjct: 101 IKFMCADVTSPDLKIKDGSIDLIFSN------------WLLMYLSDKEVELM-----AER 143 Query: 163 LV--AKPGDKLYCRLSINTQ 180 ++ KPG ++ R S Q Sbjct: 144 MIGWVKPGGYIFFRESCFHQ 163 Score = 34.3 bits (77), Expect = 0.077, Method: Composition-based stats. Identities = 23/110 (20%), Positives = 41/110 (37%), Gaps = 3/110 (2%) Query: 21 ELKSAGGLMFNTGIGQHILKNPLI--INSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKA 78 + KS+G L + G+ + + K L+P VL+VG G G + E Sbjct: 245 QYKSSGILRYERVFGEGYVSTGGFETTKEFVAKMDLKPGQKVLDVGCGIGGGDFYMAENF 304 Query: 79 K-KVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVLKTDLPFFDTCVA 127 VV +L +++ +R G + + +V FD + Sbjct: 305 DVHVVGIDLSVNMISFALERAIGLKCSVEFEVADCTTKTYPDNSFDVIYS 354 Score = 29.3 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 11/61 (18%), Positives = 23/61 (37%) Query: 110 LVGDVLKTDLPFFDTCVANLPYQISSPFVFKLLLHRPFFRCAILMFQREFALRLVAKPGD 169 + V + F + N+ Y+ S ++ + + +EF ++ KPG Sbjct: 225 IWQKVSVENDKDFQRFLDNVQYKSSGILRYERVFGEGYVSTGGFETTKEFVAKMDLKPGQ 284 Query: 170 K 170 K Sbjct: 285 K 285 >3BUS-A nrPDB Length = 273 Score = 37.8 bits (86), Expect = 0.006, Method: Composition-based stats. Identities = 16/80 (20%), Positives = 31/80 (38%), Gaps = 1/80 (1%) Query: 43 LIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAK-KVVACELDPRLVAELHKRVQGT 101 + + +I +R D VL+VG G G V+L +V + V + + R Sbjct: 48 RLTDEMIALLDVRSGDRVLDVGCGIGKPAVRLATARDVRVTGISISRPQVNQANARATAA 107 Query: 102 PVASKLQVLVGDVLKTDLPF 121 +A+++ D + Sbjct: 108 GLANRVTFSYADAMDLPFED 127 >4HGY-A nrPDB Length = 276 Score = 37.4 bits (85), Expect = 0.007, Method: Composition-based stats. Identities = 16/63 (25%), Positives = 30/63 (47%) Query: 59 VVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVLKTD 118 VLE+G GTG + L + +V E ++ +L ++ P + + ++G+ K D Sbjct: 65 PVLELGVGTGRVAFPLADLGVEVHGVESSEPMLDKLREKAAAHPNGNLVVPVLGNFAKLD 124 Query: 119 LPF 121 L Sbjct: 125 LGE 127 >1Y8C-A nrPDB Length = 246 Score = 36.6 bits (83), Expect = 0.013, Method: Composition-based stats. Identities = 18/86 (20%), Positives = 36/86 (41%), Gaps = 4/86 (4%) Query: 41 NPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQG 100 + II ++ L D L++ GTGN+T L K K A +L +++E + + Sbjct: 24 SDFIIEKCVEN-NLVFDDY-LDLACGTGNLTENLCPKFKNTWAVDLSQEMLSEAENKFRS 81 Query: 101 TPVASKLQVLVGDVLKTDLPFFDTCV 126 + +L D+ ++ + Sbjct: 82 QGLKPRLAC--QDISNLNINRKFDLI 105 >5IS8-A nrPDB Length = 381 Score = 36.6 bits (83), Expect = 0.015, Method: Composition-based stats. Identities = 22/111 (19%), Positives = 42/111 (37%), Gaps = 8/111 (7%) Query: 36 QHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAK-KVVACELDPRLVAEL 94 Q ++ +I+ +VL+VG G+G ++ + K+ A E + Sbjct: 39 QDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEA-STMAQHA 97 Query: 95 HKRVQGTPVASKLQVLVGDVLKTDLPFFDTCVANLPYQISSPFVFKLLLHR 145 V+ + ++ V+ G V + LP + IS P + L R Sbjct: 98 EVLVKSNNLTDRIVVIPGKVEEVSLPEQVDII------ISEPMGYMLFNER 142 >4IKP-A nrPDB Length = 341 Score = 36.6 bits (83), Expect = 0.015, Method: Composition-based stats. Identities = 22/111 (19%), Positives = 42/111 (37%), Gaps = 8/111 (7%) Query: 36 QHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAK-KVVACELDPRLVAEL 94 Q ++ +I+ +VL+VG G+G ++ + K+ A E + Sbjct: 25 QDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEA-STMAQHA 83 Query: 95 HKRVQGTPVASKLQVLVGDVLKTDLPFFDTCVANLPYQISSPFVFKLLLHR 145 V+ + ++ V+ G V + LP + IS P + L R Sbjct: 84 EVLVKSNNLTDRIVVIPGKVEEVSLPEQVDII------ISEPMGYMLFNER 128 >3B3J-A nrPDB Length = 480 Score = 36.6 bits (83), Expect = 0.015, Method: Composition-based stats. Identities = 22/111 (19%), Positives = 42/111 (37%), Gaps = 8/111 (7%) Query: 36 QHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAK-KVVACELDPRLVAEL 94 Q ++ +I+ +VL+VG G+G ++ + K+ A E + Sbjct: 138 QDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEA-STMAQHA 196 Query: 95 HKRVQGTPVASKLQVLVGDVLKTDLPFFDTCVANLPYQISSPFVFKLLLHR 145 V+ + ++ V+ G V + LP + IS P + L R Sbjct: 197 EVLVKSNNLTDRIVVIPGKVEEVSLPEQVDII------ISEPMGYMLFNER 241 >3CJR-A nrPDB Length = 254 Score = 36.3 bits (82), Expect = 0.018, Method: Composition-based stats. Identities = 19/77 (24%), Positives = 34/77 (44%), Gaps = 1/77 (1%) Query: 53 ALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKLQVLVG 112 LRP D VL++G G+G + + + K + ++DP ++ + + V + Sbjct: 117 HLRPGDKVLDLGTGSGVLAIAAEKLGGKALGVDIDPMVLPQAEANAKRNGVRPRFLEGSL 176 Query: 113 DVLKTDLPFFDTCVANL 129 + FD VANL Sbjct: 177 EA-ALPFGPFDLLVANL 192 >3EVZ-A nrPDB Length = 230 Score = 36.3 bits (82), Expect = 0.019, Method: Composition-based stats. Identities = 29/124 (23%), Positives = 45/124 (36%), Gaps = 4/124 (3%) Query: 12 RRGRQEQRRELKSAGGLMFNTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMT 71 R+ R + + A + L I I K LR +V LE+G G M Sbjct: 12 RQARILYNKAIAKAL-FGLDIEYHPKGLVTTPISRYIFLKTFLRGGEVALEIGTGHTAMM 70 Query: 72 VKLLEK--AKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVLKTDL-PFFDTCVAN 128 + EK KV A E+D + ++ +L G ++K + FD + Sbjct: 71 ALMAEKFFNCKVTATEVDEEFFEYARRNIERNNSNVRLVKSNGGIIKGVVEGTFDVIFSA 130 Query: 129 LPYQ 132 PY Sbjct: 131 PPYY 134 >1JG3-A nrPDB Length = 235 Score = 36.3 bits (82), Expect = 0.020, Method: Composition-based stats. Identities = 26/108 (24%), Positives = 48/108 (44%), Gaps = 13/108 (12%) Query: 42 PLIINSIIDKAALRPTDVVLEVGPGTG---NMTVKLLEKAKKVVACELDPRLVAELHKRV 98 P ++ +++ A L+P +LEVG G+G + ++++ V E P LV + + Sbjct: 77 PHMVAIMLEIANLKPGMNILEVGTGSGWNAALISEIVK--TDVYTIERIPELVEFAKRNL 134 Query: 99 QGTPVASKLQVLVGDVLKTDLPFFD-----TCVANLPYQISSPFVFKL 141 + V + V++GD K P A P +I P + +L Sbjct: 135 ERAGV-KNVHVILGDGSK-GFPPKAPYDVIIVTAGAP-KIPEPLIEQL 179 >2YXE-A nrPDB Length = 215 Score = 35.9 bits (81), Expect = 0.021, Method: Composition-based stats. Identities = 24/105 (22%), Positives = 45/105 (42%), Gaps = 8/105 (7%) Query: 15 RQEQRRELKSAGGLM---FNTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTG--- 68 R+E E + G GQ + ++ + + L+P VLE+G G G Sbjct: 34 REEFLPEHLKEYAYVDTPLEIGYGQT-ISAIHMVGMMCELLDLKPGMKVLEIGTGCGYHA 92 Query: 69 NMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGD 113 +T +++ + VV+ E P L + + ++ + V+VGD Sbjct: 93 AVTAEIVGEDGLVVSIERIPELAEKAERTLR-KLGYDNVIVIVGD 136 >5FAD-A nrPDB Length = 161 Score = 35.9 bits (81), Expect = 0.022, Method: Composition-based stats. Identities = 21/123 (17%), Positives = 47/123 (38%), Gaps = 5/123 (4%) Query: 42 PLIINSIIDKAALRPTDVVLEVGPGTG--NMTVKLLEKAKKVVACELDPRLVAELHKRVQ 99 ++ +++ A + D+V ++G G G +T KK V E++ + E ++ Sbjct: 14 EKVVRRMLEIAKVSQDDIVYDLGCGDGRIIITAAKDFNVKKAVGVEINDERIREALANIE 73 Query: 100 GTPVASKLQVLVGDVLKTDLPFFDTCVANLPYQISSPFVFKLLLHRPFFRCAILMFQREF 159 V + ++ G+ + D+ L ++ KL + + EF Sbjct: 74 KNGVTGRASIVKGNFFEVDISEATVVTMFLLTNVNEMLKPKLEKE---LKPGTRVVSHEF 130 Query: 160 ALR 162 +R Sbjct: 131 EIR 133 >6CU3-A nrPDB Length = 336 Score = 35.9 bits (81), Expect = 0.024, Method: Composition-based stats. Identities = 15/79 (18%), Positives = 34/79 (43%), Gaps = 5/79 (6%) Query: 46 NSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELD-PRLVAELHKRVQGTPVA 104 N+I+ L VVL++G GTG + + + K +D ++ + + V + Sbjct: 41 NAILQNKHLFKDKVVLDIGCGTGILCLFAAKAGAK-RVIGIDMSDIIDKARQIVSDNGYS 99 Query: 105 SKLQVLVG---DVLKTDLP 120 ++++ G D+ + Sbjct: 100 HVIELIKGKVEDIAQLPFG 118 >2YR0-A nrPDB Length = 263 Score = 35.9 bits (81), Expect = 0.024, Method: Composition-based stats. Identities = 18/83 (21%), Positives = 37/83 (44%), Gaps = 3/83 (3%) Query: 40 KNPLIINSIIDKAALRPTDVVL-EVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRV 98 I ++ + + V E+G GTG + + L+ + + +A + D ++ +++ Sbjct: 22 VAGQIATAMASAVHPKGEEPVFLELGVGTGRIALPLIARGYRYIALDADAAMLEVFRQKI 81 Query: 99 QGTPVASKLQVLVGDVLKTDLPF 121 G V K+QV+ D LP Sbjct: 82 AG--VDRKVQVVQADARAIPLPD 102 >3GDH-A nrPDB Length = 241 Score = 35.9 bits (81), Expect = 0.026, Method: Composition-based stats. Identities = 19/75 (25%), Positives = 34/75 (45%), Gaps = 5/75 (6%) Query: 46 NSIIDKAALR-----PTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQG 100 I + A R DVV++ G G T++ +V+A ++DP +A + Sbjct: 63 EKIAEHIAGRVSQSFKCDVVVDAFCGVGGNTIQFALTGMRVIAIDIDPVKIALARNNAEV 122 Query: 101 TPVASKLQVLVGDVL 115 +A K++ + GD L Sbjct: 123 YGIADKIEFICGDFL 137 >3EGI-A nrPDB Length = 206 Score = 35.9 bits (81), Expect = 0.026, Method: Composition-based stats. Identities = 19/75 (25%), Positives = 34/75 (45%), Gaps = 5/75 (6%) Query: 46 NSIIDKAALR-----PTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQG 100 I + A R DVV++ G G T++ +V+A ++DP +A + Sbjct: 28 EKIAEHIAGRVSQSFKCDVVVDAFCGVGGNTIQFALTGMRVIAIDIDPVKIALARNNAEV 87 Query: 101 TPVASKLQVLVGDVL 115 +A K++ + GD L Sbjct: 88 YGIADKIEFICGDFL 102 >5JMQ-A nrPDB Length = 446 Score = 35.5 bits (80), Expect = 0.033, Method: Composition-based stats. Identities = 19/81 (23%), Positives = 29/81 (35%), Gaps = 3/81 (3%) Query: 48 IIDKAALRPTDVVLEVGPGTGNMTVKLLEKA--KKVVACELDPRLVAELHKRVQGTPVAS 105 I+ V+L+VG GTG +++ A K V A E + + V A Sbjct: 142 ILQNKESLKDKVILDVGCGTGIISLFCAHHARPKAVYAVEA-SDMAQHTSQLVLQNGFAD 200 Query: 106 KLQVLVGDVLKTDLPFFDTCV 126 + V V LP + Sbjct: 201 TITVFQQKVEDVVLPEKVDVL 221 >3R0Q-C nrPDB Length = 376 Score = 35.1 bits (79), Expect = 0.037, Method: Composition-based stats. Identities = 17/82 (20%), Positives = 32/82 (39%), Gaps = 2/82 (2%) Query: 46 NSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAK-KVVACELDPRLVAELHKRVQGTPVA 104 N++ VL+VG G+G + + + KV A E ++ V+ + Sbjct: 53 NAVFQNKHHFEGKTVLDVGTGSGILAIWSAQAGARKVYAVEA-TKMADHARALVKANNLD 111 Query: 105 SKLQVLVGDVLKTDLPFFDTCV 126 ++V+ G V LP + Sbjct: 112 HIVEVIEGSVEDISLPEKVDVI 133 >3BKX-A nrPDB Length = 275 Score = 34.7 bits (78), Expect = 0.054, Method: Composition-based stats. Identities = 15/87 (17%), Positives = 35/87 (40%), Gaps = 9/87 (10%) Query: 47 SIIDKAALRPTDVVLEVGPGTGNMTVKLLEK---AKKVVACELDPR------LVAELHKR 97 +I + ++P + +LE+G G G+++ L ++ + V ++ + + Sbjct: 34 AIAEAWQVKPGEKILEIGCGQGDLSAVLADQVGSSGHVTGIDIASPDYGAPLTLGQAWNH 93 Query: 98 VQGTPVASKLQVLVGDVLKTDLPFFDT 124 + P+ +L V L DL Sbjct: 94 LLAGPLGDRLTVHFNTNLSDDLGPIAD 120 >2B25-A nrPDB Length = 336 Score = 34.7 bits (78), Expect = 0.054, Method: Composition-based stats. Identities = 21/109 (19%), Positives = 38/109 (34%), Gaps = 16/109 (14%) Query: 19 RRELKSAGGLMFNTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKA 78 RR ++ G K+ IN I+ + P D VLE G G+G M++ L + Sbjct: 71 RRPALEDYVVLMKRGTAITFPKD---INMILSMMDINPGDTVLEAGSGSGGMSLFLSKAV 127 Query: 79 ---KKVVACELDPRLVAELHKRVQG----------TPVASKLQVLVGDV 114 +V++ E+ K + + + D+ Sbjct: 128 GSQGRVISFEVRKDHHDLAKKNYKHWRDSWKLSHVEEWPDNVDFIHKDI 176 >5GM1-A nrPDB Length = 297 Score = 34.3 bits (77), Expect = 0.065, Method: Composition-based stats. Identities = 13/74 (17%), Positives = 31/74 (41%), Gaps = 1/74 (1%) Query: 45 INSIIDKAALRPTDVVLEVGPGTGNMTVKLL-EKAKKVVACELDPRLVAELHKRVQGTPV 103 + +I+ + +L++G GTG +K ++ V + +A ++ G + Sbjct: 66 TDYLIETLDPKAGQHLLDIGCGTGRTALKAARQRGIAVTGVAVSKEQIAAANRLAAGHGL 125 Query: 104 ASKLQVLVGDVLKT 117 +L V D ++ Sbjct: 126 TERLTFEVADAMRL 139 >5DST-A nrPDB Length = 332 Score = 34.3 bits (77), Expect = 0.067, Method: Composition-based stats. Identities = 19/76 (25%), Positives = 35/76 (46%), Gaps = 2/76 (2%) Query: 46 NSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKA-KKVVACELDPRLVAELHKRVQGTPVA 104 NS+ + VVL+VG GTG +++ + KKV E + K ++ + Sbjct: 39 NSMYHNKHVFKDKVVLDVGSGTGILSMFAAKAGAKKVFGIEC-SSISDYSEKIIKANHLD 97 Query: 105 SKLQVLVGDVLKTDLP 120 + + + G V + +LP Sbjct: 98 NIITIFKGKVEEVELP 113 >3SM3-A nrPDB Length = 235 Score = 34.3 bits (77), Expect = 0.069, Method: Composition-based stats. Identities = 15/79 (18%), Positives = 31/79 (39%), Gaps = 6/79 (7%) Query: 54 LRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASK------L 107 L+ D +L++G G+G ++++L K V +++ + + + K Sbjct: 28 LQEDDEILDIGCGSGKISLELASKGYSVTGIDINSEAIRLAETAARSPGLNQKTGGKAEF 87 Query: 108 QVLVGDVLKTDLPFFDTCV 126 +V L FD V Sbjct: 88 KVENASSLSFHDSSFDFAV 106 >1I9G-A nrPDB Length = 280 Score = 34.3 bits (77), Expect = 0.075, Method: Composition-based stats. Identities = 20/82 (24%), Positives = 36/82 (43%), Gaps = 5/82 (6%) Query: 47 SIIDKAALRPTDVVLEVGPGTGNMTVKLLE---KAKKVVACELDPRLVAELHKRVQGTPV 103 I+ + + P VLE G G+G +T+ LL A +V++ E + V G Sbjct: 90 QIVHEGDIFPGARVLEAGAGSGALTLSLLRAVGPAGQVISYEQRADHAEHARRNVSGCYG 149 Query: 104 A--SKLQVLVGDVLKTDLPFFD 123 +++V D+ ++LP Sbjct: 150 QPPDNWRLVVSDLADSELPDGS 171 >4INE-A nrPDB Length = 454 Score = 33.9 bits (76), Expect = 0.085, Method: Composition-based stats. Identities = 26/178 (14%), Positives = 60/178 (33%), Gaps = 23/178 (12%) Query: 34 IGQHILKNPL---IINSIIDKAALRPTDVVLEVGPGTGNMTVKLL-EKAKKVVACELDPR 89 G + + + I +P +L++G G G ++ E V +L Sbjct: 216 FGVNFISPGGYDENLKIIKRFGDFKPGQTMLDIGVGIGGGARQVADEFGVHVHGIDLSSN 275 Query: 90 LVAELHKRVQGTPVASKLQVLVGDVLKTDLPFFD-------TCVANLPYQISSPFVFKLL 142 ++A +R+ S+++ + D L C+ ++P + +F + Sbjct: 276 MLAIALERLHEEK-DSRVKYSITDALVYQFEDNSFDYVFSRDCIQHIP---DTEKLFSRI 331 Query: 143 LH--RPFFRCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKV-GKNNFR 197 +P + I M+ + + DK ++ L + + + K F Sbjct: 332 YKALKPGGKVLITMYGKGYGE-----QSDKFKTYVAQRAYFLKNLKEIADIANKTGFV 384 >2PJD-A nrPDB Length = 343 Score = 33.6 bits (75), Expect = 0.10, Method: Composition-based stats. Identities = 17/87 (19%), Positives = 32/87 (36%), Gaps = 4/87 (4%) Query: 48 IIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKK--VVACELDPRLVAELHKRVQGTPVAS 105 ++ VL+VG G G ++V + K + C++ V + V Sbjct: 188 LLSTLTPHTKGKVLDVGCGAGVLSVAFARHSPKIRLTLCDVSAPAVEASRATLAANGVEG 247 Query: 106 KLQVLVGDVLKTDLPFFDTCVANLPYQ 132 +V +V FD ++N P+ Sbjct: 248 --EVFASNVFSEVKGRFDMIISNPPFH 272 >5KPG-A nrPDB Length = 397 Score = 33.6 bits (75), Expect = 0.12, Method: Composition-based stats. Identities = 12/71 (16%), Positives = 35/71 (49%), Gaps = 3/71 (4%) Query: 50 DKAALRPTDVVLEVGPGTGNMTVKLLE--KAKKVVACELDPRLVAELHKRVQGTPVASKL 107 ++A ++ +L++G G G++T+ + + + KV + + + + S + Sbjct: 162 ERAQIKDGQSILDLGCGHGSLTLHVAQKYRGCKVTGITNSVSQKEFIMDQCKKLDL-SNV 220 Query: 108 QVLVGDVLKTD 118 ++++ DV K + Sbjct: 221 EIILEDVTKFE 231 >6BQC-A nrPDB Length = 383 Score = 33.6 bits (75), Expect = 0.13, Method: Composition-based stats. Identities = 18/84 (21%), Positives = 33/84 (39%), Gaps = 6/84 (7%) Query: 45 INSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAK-KVVACELDPRLVAELHKRVQGTPV 103 + I +K L+P VL++G G G + + VV + +R +G Sbjct: 157 LKMICEKLQLKPGMRVLDIGCGWGGLAHYMASNYDVSVVGVTISAEQQKMAQERCEGL-- 214 Query: 104 ASKLQVLVGDVLKTDLPFFDTCVA 127 + +L+ D + FD V+ Sbjct: 215 --DVTILLQDYRDLND-QFDRIVS 235 >2IP2-A nrPDB Length = 334 Score = 33.6 bits (75), Expect = 0.13, Method: Composition-based stats. Identities = 12/66 (18%), Positives = 28/66 (42%), Gaps = 2/66 (3%) Query: 61 LEVGPGTGNMTVKLLEKAKKVVACELDPR-LVAELHKRVQGTPVASKLQVLVGDVLKTDL 119 ++VG G+G +T +L+ LD + + ++ ++ GD+L+ ++ Sbjct: 172 VDVGGGSGELTKAILQAEPSARGVMLDREGSLGVARDNLSSLLAGERVSLVGGDMLQ-EV 230 Query: 120 PFFDTC 125 P Sbjct: 231 PSNGDI 236 >2IFT-A nrPDB Length = 201 Score = 33.2 bits (74), Expect = 0.15, Method: Composition-based stats. Identities = 23/112 (20%), Positives = 45/112 (40%), Gaps = 9/112 (8%) Query: 66 GTGNMT-VKLLEKAKKVVACELDPRLVAELHKRVQG-TPVASKLQVLVGDVLKT-----D 118 G+G++ L +AKKV ELD + +L K +Q + + +V+ L + Sbjct: 63 GSGSLGFEALSRQAKKVTFLELDKTVANQLKKNLQTLKCSSEQAEVINQSSLDFLKQPQN 122 Query: 119 LPFFDTCVANLPYQ--ISSPFVFKLLLHRPFFRCAILMFQREFALRLVAKPG 168 P FD + P+ ++ + L + A++ + E L+ Sbjct: 123 QPHFDVVFLDPPFHFNLAEQAISLLCENNWLKPNALIYVETEKDKPLITPEN 174 >3DOU-A nrPDB Length = 191 Score = 33.2 bits (74), Expect = 0.15, Method: Composition-based stats. Identities = 11/33 (33%), Positives = 19/33 (57%) Query: 54 LRPTDVVLEVGPGTGNMTVKLLEKAKKVVACEL 86 +R D V+E+G G T L A+K+++ +L Sbjct: 23 VRKGDAVIEIGSSPGGWTQVLNSLARKIISIDL 55 >2B3T-A nrPDB Length = 276 Score = 33.2 bits (74), Expect = 0.16, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 28/80 (35%), Gaps = 2/80 (2%) Query: 54 LRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAE-LHKRVQGTPVASKLQVLVG 112 +L++G GTG + + L + +D A L +R + +L Sbjct: 107 PEQPCRILDLGTGTGAIALALASERPDCEIIAVDRMPDAVSLAQRNAQHLAIKNIHILQS 166 Query: 113 DVLKTDLP-FFDTCVANLPY 131 D F V+N PY Sbjct: 167 DWFSALAGQQFAMIVSNPPY 186 >3X0D-A nrPDB Length = 655 Score = 33.2 bits (74), Expect = 0.16, Method: Composition-based stats. Identities = 28/113 (24%), Positives = 42/113 (37%), Gaps = 18/113 (15%) Query: 60 VLEVGPGTGNMTVKLL-EKAKKVVACELDPRLVAELHKRVQGTPVASKLQVLVG---DVL 115 VL++G GTG +++ E A KV A E+ + +P + K+ V+ DV Sbjct: 76 VLDIGTGTGLLSLMAAREGADKVTALEVFKPMGDCARHITSNSPWSDKITVISERSTDVS 135 Query: 116 KTDLPFFDTCVANLPYQISSPFVFKLLLHRPFFRCAILMFQREFALRLVAKPG 168 + D VA + L +E RL AKPG Sbjct: 136 QIGGSRADIIVAE-------------VFDTELIGEGALRTFKEALERL-AKPG 174 >4KRG-A nrPDB Length = 466 Score = 33.2 bits (74), Expect = 0.16, Method: Composition-based stats. Identities = 17/83 (20%), Positives = 31/83 (37%), Gaps = 5/83 (6%) Query: 48 IIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKL 107 I+ V+++G G G T L E A+ V++ + + + +R + Sbjct: 49 ILSSLPHLTNKDVVDIGAGIGRFTTVLAETARWVLSTDFIESFIEKNQER---NAHMGNI 105 Query: 108 QVLVGDV--LKTDLPFFDTCVAN 128 +GD L+ D D N Sbjct: 106 SYQIGDAVHLQMDEKSVDLVFTN 128 >5U8S-7 nrPDB Length = 845 Score = 32.8 bits (73), Expect = 0.19, Method: Composition-based stats. Identities = 23/121 (19%), Positives = 43/121 (35%), Gaps = 8/121 (6%) Query: 46 NSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVAS 105 + +D + +LE GP M K+ + V +LD L + K +QGT Sbjct: 44 DENLDAENIEQH--LLEKGPKYMAMLQKVANRELNSVIIDLDDILQYQNEKFLQGTQADD 101 Query: 106 KLQVLVGDVLKTDLPFFDTCVANLPYQISSPFVFKLLLHRPFFRCAILMFQREFALRLVA 165 + + + F N+P K + ++ IL +R R+++ Sbjct: 102 LVSAIQQNANHFTELFCRAIDNNMP------LPTKEIDYKDDVLDVILNQRRLRNERMLS 155 Query: 166 K 166 Sbjct: 156 D 156 >5I2H-A nrPDB Length = 364 Score = 32.8 bits (73), Expect = 0.19, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 34/81 (41%), Gaps = 1/81 (1%) Query: 47 SIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDP-RLVAELHKRVQGTPVAS 105 I+ + V+L+V G+G T+ +L+K D ++ + + T V Sbjct: 187 KILKDNSGSSGRVLLDVAGGSGIYTMAVLQKYPTWRGIIFDRPEVLKIAAELAEQTGVRD 246 Query: 106 KLQVLVGDVLKTDLPFFDTCV 126 +L++ GD+ P D + Sbjct: 247 RLELHAGDMWVDPFPPADDIL 267 >4QDJ-A nrPDB Length = 238 Score = 32.8 bits (73), Expect = 0.20, Method: Composition-based stats. Identities = 10/51 (19%), Positives = 23/51 (45%) Query: 56 PTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASK 106 P +V + G G G++++ L + V ++ ++V E ++ Q Sbjct: 62 PGLLVCDAGCGVGSLSIPLAQAGALVYGSDISEKMVGEAQQKAQEVLAYGN 112 >3TM5-A nrPDB Length = 373 Score = 32.4 bits (72), Expect = 0.23, Method: Composition-based stats. Identities = 24/125 (19%), Positives = 50/125 (40%), Gaps = 12/125 (9%) Query: 43 LIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEK--AKKVVACELDPRLVAELHKRVQG 100 I N++I+ A L VL+ G+G + ++L + + +++ E + + Sbjct: 205 SIANAMIELAEL-DGGSVLDPMCGSGTILIELALRRYSGEIIGIEKYRKHLIGAEMNALA 263 Query: 101 TPVASKLQVLVGDVLKTD--LPFFDTCVANLPYQISSPFVFKLLLHRPFFRCAILMFQRE 158 V K++ + GD + + D ++NLPY + + + + F E Sbjct: 264 AGVLDKIKFIQGDATQLSQYVDSVDFAISNLPYGLK-------IGKKSMIPDLYMKFFNE 316 Query: 159 FALRL 163 A L Sbjct: 317 LAKVL 321 >4MTL-A nrPDB Length = 244 Score = 32.4 bits (72), Expect = 0.23, Method: Composition-based stats. Identities = 19/102 (18%), Positives = 39/102 (38%), Gaps = 8/102 (7%) Query: 60 VLEVGPGTGNMTVKLLEKAKKVVACELDPRL----VAELHKRVQGTPVASKL-QVLVGDV 114 +LE+G G G +++ +V A +L L L +Q T ++ +++ G+ Sbjct: 96 ILEIGAGPGLVSIVASILGAQVTATDLPDVLGNLQYNLLKNTLQCTAHLPEVKELVWGED 155 Query: 115 LKTDLPFFDTCVANLPYQISSPFVFKLLLHRPFFRCAILMFQ 156 L + P Y ++S V+ + + Q Sbjct: 156 LDKNFPKSAFYYD---YVLASDVVYHHYFLDKLLTTMVYLSQ 194 >3D2L-A nrPDB Length = 243 Score = 32.4 bits (72), Expect = 0.28, Method: Composition-based stats. Identities = 14/68 (20%), Positives = 29/68 (42%), Gaps = 3/68 (4%) Query: 54 LRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGD 113 + P + ++G GTG T+ L + +V +L ++ ++ T V D Sbjct: 31 VEPGKRIADIGCGTGTATLLLADHY-EVTGVDLSEEMLEIAQEKAMETNRHVDFWV--QD 87 Query: 114 VLKTDLPF 121 + + +LP Sbjct: 88 MRELELPE 95 >3MGG-A nrPDB Length = 276 Score = 32.4 bits (72), Expect = 0.30, Method: Composition-based stats. Identities = 15/75 (20%), Positives = 30/75 (40%), Gaps = 5/75 (6%) Query: 56 PTDVVLEVGPGTGNMTVKLLEKA--KKVVACELDPRLVAELHKRVQGTPVASKLQVLVGD 113 P VLE G G G TV L + ++ + ++ P + + + + ++ L + Sbjct: 37 PGAKVLEAGCGIGAQTVILAKNNPDAEITSIDISPESLEKARENTE-KNGIKNVKFLQAN 95 Query: 114 V--LKTDLPFFDTCV 126 + L + FD Sbjct: 96 IFSLPFEDSSFDHIF 110 >5XJ2-A nrPDB Length = 454 Score = 32.0 bits (71), Expect = 0.30, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 30/67 (44%), Gaps = 4/67 (5%) Query: 42 PLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGT 101 + + ID A L+ DV+++ G G + + + + K+V E L+ E + Q Sbjct: 290 EKLYQTAIDFAELKKDDVIIDAYSGIGTIGLSVAKHVKEVYGVE----LIPEAVENSQKN 345 Query: 102 PVASKLQ 108 +K+ Sbjct: 346 ASLNKIT 352 >5ZW4-A nrPDB Length = 225 Score = 32.0 bits (71), Expect = 0.32, Method: Composition-based stats. Identities = 15/84 (17%), Positives = 34/84 (40%), Gaps = 6/84 (7%) Query: 52 AALRPTDVVLEVGPGTG--NMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKLQV 109 +++ +LE+G G + + L + ++ E + + E ++ + ++ V Sbjct: 50 LSVKQPKKILEIGTAIGYSAIRMALELPSAEIYTIERNEKRHEEAVNNIKEFQLDDRIHV 109 Query: 110 LVGDVLKTDLPFFDTCVANLPYQI 133 GD L +L A PY + Sbjct: 110 FYGDAL--ELADAVHVTA--PYDV 129 >3SVZ-A nrPDB Length = 263 Score = 32.0 bits (71), Expect = 0.33, Method: Composition-based stats. Identities = 16/89 (17%), Positives = 33/89 (37%), Gaps = 4/89 (4%) Query: 41 NPLIINSIIDKAA-LRPTDVVLEVGPGTGNMTVKLLEKAK-KVVACELDPRLVAELHKRV 98 +P + L + ++G GTG T+ L + K ++ +L P + ++ Sbjct: 36 SPEATRKAVSFINELTDDAKIADIGCGTGGQTLFLADYVKGQITGIDLFPDFIEIFNENA 95 Query: 99 QGTPVASKLQVLVG--DVLKTDLPFFDTC 125 A +++ + G D L D Sbjct: 96 VKANCADRVKGITGSMDNLPFQNEELDLI 124 >2P35-A nrPDB Length = 259 Score = 31.6 bits (70), Expect = 0.41, Method: Composition-based stats. Identities = 13/76 (17%), Positives = 28/76 (36%), Gaps = 2/76 (2%) Query: 61 LEVGPGTGNMTVKLLEK--AKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVLKTD 118 ++G G GN T L ++ + + D ++ + R+ T K D Sbjct: 38 YDLGCGPGNSTELLTDRYGVNVITGIDSDDDMLEKAADRLPNTNFGKADLATWKPAQKAD 97 Query: 119 LPFFDTCVANLPYQIS 134 L + + +P ++ Sbjct: 98 LLYANAVFQWVPDHLA 113 >3HM2-A nrPDB Length = 178 Score = 31.6 bits (70), Expect = 0.43, Method: Composition-based stats. Identities = 17/95 (17%), Positives = 36/95 (37%), Gaps = 5/95 (5%) Query: 35 GQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVAC--ELDPRLVA 92 GQ L + I A +P + + ++G G+G++ ++ L + A E+ Sbjct: 6 GQ--LTKQHVRALAISALAPKPHETLWDIGGGSGSIAIEWLRSTPQTTAVCFEISEERRE 63 Query: 93 ELHKRVQGTPVASKLQVLVGDVLKT-DLPFFDTCV 126 + V+ ++ V G D+P + Sbjct: 64 RILSNAINLGVSDRIAVQQGAPRAFDDVPDNPDVI 98 >3JWJ-A nrPDB Length = 202 Score = 31.6 bits (70), Expect = 0.43, Method: Composition-based stats. Identities = 16/89 (17%), Positives = 37/89 (41%), Gaps = 7/89 (7%) Query: 40 KNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKA--KKVVACELDPRLVAELHKR 97 N +N ++ V+++G G GN+ LL+ + +++ ++ R + +R Sbjct: 3 LNQQRMNGVVAALKQSNARRVIDLGCGQGNLLKILLKDSFFEQITGVDVSYRSLEIAQER 62 Query: 98 VQGTPV----ASKLQVLVGDVLKTDLPFF 122 + + +LQ++ G L F Sbjct: 63 LDRLRLPRNQWERLQLIQG-ALTYQDKRF 90 >3Q7E-A nrPDB Length = 349 Score = 31.6 bits (70), Expect = 0.44, Method: Composition-based stats. Identities = 20/76 (26%), Positives = 34/76 (44%), Gaps = 2/76 (2%) Query: 46 NSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAK-KVVACELDPRLVAELHKRVQGTPVA 104 NS+ L VVL+VG GTG + + + KV+ E + K V+ + Sbjct: 56 NSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIEC-SSISDYAVKIVKANKLD 114 Query: 105 SKLQVLVGDVLKTDLP 120 + ++ G V + +LP Sbjct: 115 HVVTIIKGKVEEVELP 130 >3G5T-A nrPDB Length = 299 Score = 31.6 bits (70), Expect = 0.45, Method: Composition-based stats. Identities = 14/77 (18%), Positives = 35/77 (45%), Gaps = 6/77 (7%) Query: 47 SIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAK---KVVACELDPRLVAELHKRVQGTPV 103 +ID+ ++++VG G G T+++ ++ K +++ +L ++ +G+P Sbjct: 27 KMIDEYHDGERKLLVDVGCGPGTATLQMAQELKPFEQIIGSDLSATMIKTAEVIKEGSPD 86 Query: 104 ASK---LQVLVGDVLKT 117 K ++ D K Sbjct: 87 TYKNVSFKISSSDDFKF 103 >6MRO-A nrPDB Length = 194 Score = 31.6 bits (70), Expect = 0.47, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 34/73 (46%), Gaps = 3/73 (4%) Query: 46 NSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVAS 105 ++I+ +RP L++G G G + L + V +L R +++ + Sbjct: 23 QALIESGEIRPG-RALDIGCGRGENAIMLAKNGCDVTGIDLAKRAISDAKAKAIER--HV 79 Query: 106 KLQVLVGDVLKTD 118 K+ +VG+VL+ D Sbjct: 80 KVNFIVGNVLEMD 92 >4OA5-A nrPDB Length = 227 Score = 31.2 bits (69), Expect = 0.57, Method: Composition-based stats. Identities = 15/86 (17%), Positives = 31/86 (36%), Gaps = 6/86 (6%) Query: 33 GIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKK---VVACELDPR 89 + Q ++ +I A + ++EVG G + + + E D Sbjct: 45 RMAQLGTVEGQMLQLLIRMAGI---HSIVEVGTCVGFSAICMAHALPSKGHIYTIEKDYE 101 Query: 90 LVAELHKRVQGTPVASKLQVLVGDVL 115 V ++ + + K+ VL G+ L Sbjct: 102 NVVTANQNIVNCKLEDKITVLHGEAL 127 >6GKZ-A nrPDB Length = 351 Score = 31.2 bits (69), Expect = 0.62, Method: Composition-based stats. Identities = 13/75 (17%), Positives = 34/75 (45%), Gaps = 3/75 (4%) Query: 44 IINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKK--VVACELDPRLVAELHKRVQGT 101 +++ ++A ++ VL++G G G +T+ + +K K V A + + + Sbjct: 111 MLDLYCERAQIQDGQSVLDLGCGQGALTLHVAQKYKNCRVTAVTNSVSQKEYIEEESRRR 170 Query: 102 PVASKLQVLVGDVLK 116 + ++V + D+ Sbjct: 171 NLL-NVEVKLADITT 184 >3L8D-A nrPDB Length = 242 Score = 30.9 bits (68), Expect = 0.68, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 28/70 (40%), Gaps = 4/70 (5%) Query: 54 LRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGD 113 ++ VL+VG G G T KL K V ++ ++ + +R +G L + GD Sbjct: 51 VKKEAEVLDVGCGDGYGTYKLSRTGYKAVGVDISEVMIQKGKERGEG----PDLSFIKGD 106 Query: 114 VLKTDLPFFD 123 + Sbjct: 107 LSSLPFENEQ 116 >3NJR-A nrPDB Length = 204 Score = 30.9 bits (68), Expect = 0.68, Method: Composition-based stats. Identities = 11/82 (13%), Positives = 34/82 (41%), Gaps = 5/82 (6%) Query: 38 ILKNPLIINSIIDKA-----ALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVA 92 + I S + A R +++ ++G G+G+++V+ + + E + Sbjct: 32 FAHDGQITKSPMRALTLAALAPRRGELLWDIGGGSGSVSVEWCLAGGRAITIEPRADRIE 91 Query: 93 ELHKRVQGTPVASKLQVLVGDV 114 + K + ++ +++ + G Sbjct: 92 NIQKNIDTYGLSPRMRAVQGTA 113 >1MJF-A nrPDB Length = 281 Score = 30.9 bits (68), Expect = 0.70, Method: Composition-based stats. Identities = 9/45 (20%), Positives = 20/45 (44%), Gaps = 1/45 (2%) Query: 56 PTDVVLEVGPGTGNMTVKLLEK-AKKVVACELDPRLVAELHKRVQ 99 VL +G G G ++L+ +V+ E+D ++ ++ Sbjct: 75 KPKRVLVIGGGDGGTVREVLQHDVDEVIMVEIDEDVIMVSKDLIK 119 >4G56-A nrPDB Length = 657 Score = 30.9 bits (68), Expect = 0.73, Method: Composition-based stats. Identities = 18/89 (20%), Positives = 37/89 (41%), Gaps = 7/89 (7%) Query: 44 IINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAK------KVVACELDPRLVAELHKR 97 +++ + ++ +++ +G G G + L AK KV A E +P V L Sbjct: 365 LLDRVPEEEKETNIQILMVLGAGRGPLVNASLRAAKQAERKIKVYAVEKNPNAVITLEG- 423 Query: 98 VQGTPVASKLQVLVGDVLKTDLPFFDTCV 126 + S++ V+ GD+ + P + Sbjct: 424 WRYEEWGSQVTVVSGDMREWKAPEKADII 452 >1F3L-A nrPDB Length = 321 Score = 30.9 bits (68), Expect = 0.75, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 36/76 (47%), Gaps = 2/76 (2%) Query: 46 NSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKA-KKVVACELDPRLVAELHKRVQGTPVA 104 + I + VVL+VG GTG +++ + KKV+A + ++ + ++ + Sbjct: 35 DFIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAKKVIAVD-QSEILYQAMDIIRLNKLE 93 Query: 105 SKLQVLVGDVLKTDLP 120 + ++ G + + LP Sbjct: 94 DTIVLIKGKIEEVSLP 109 >4RYL-A nrPDB Length = 340 Score = 30.9 bits (68), Expect = 0.77, Method: Composition-based stats. Identities = 14/75 (18%), Positives = 32/75 (42%) Query: 46 NSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVAS 105 + I + VVL+VG GTG +++ + K V ++ + ++ + Sbjct: 54 DFIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAKKVLGVDQSEILYQAMDIIRLNKLED 113 Query: 106 KLQVLVGDVLKTDLP 120 + ++ G + + LP Sbjct: 114 TITLIKGKIEEVHLP 128 >5EGS-A nrPDB Length = 376 Score = 30.5 bits (67), Expect = 0.87, Method: Composition-based stats. Identities = 24/127 (18%), Positives = 54/127 (42%), Gaps = 8/127 (6%) Query: 5 KSGAIGRRRGRQEQRRELKSAGGLMFNTGIGQHILKNPLIINS----IIDKAALRPTDVV 60 + A+ R R + +R +L + + + ++ + + ++ I+ A V Sbjct: 30 REAALERPRRTKRERDQLY--YECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTV 87 Query: 61 LEVGPGTGNMTVKLLEKAK-KVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVLKTDL 119 L+VG GTG +++ + +V A E + + + V+ + ++ VL G V +L Sbjct: 88 LDVGAGTGILSIFCAQAGARRVYAVEA-SAIWQQAREVVRFNGLEDRVHVLPGPVETVEL 146 Query: 120 PFFDTCV 126 P + Sbjct: 147 PEQVDAI 153 >3LPM-A nrPDB Length = 259 Score = 30.5 bits (67), Expect = 0.87, Method: Composition-based stats. Identities = 23/112 (20%), Positives = 45/112 (40%), Gaps = 5/112 (4%) Query: 60 VLEVGPGTGNMTVKLLEKAK-KVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVLK-T 117 ++++ G G + + L + K K+V E+ RL + V + +++++ D+ K T Sbjct: 53 IIDLCSGNGIIPLLLSTRTKAKIVGVEIQERLADMAKRSVAYNQLEDQIEIIEYDLKKIT 112 Query: 118 DLPFFDT---CVANLPYQISSPFVFKLLLHRPFFRCAILMFQREFALRLVAK 166 DL + N PY + K +M E +R+ A Sbjct: 113 DLIPKERADIVTCNPPYFATPDTSLKNTNEHFRIARHEVMCTLEDTIRVAAS 164 >3OU6-A nrPDB Length = 218 Score = 30.5 bits (67), Expect = 0.93, Method: Composition-based stats. Identities = 21/88 (23%), Positives = 35/88 (39%), Gaps = 13/88 (14%) Query: 49 IDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKLQ 108 + +R VLE+ GTG T L A +V A + ++AE G ++ Sbjct: 41 LRAGNIRGD--VLELASGTGYWTRHLSGLADRVTALDGSAEMIAEA-----GRHGLDNVE 93 Query: 109 VLVGDVL------KTDLPFFDTCVANLP 130 D+ + D FF +A++P Sbjct: 94 FRQQDLFDWTPDRQWDAVFFAHWLAHVP 121 >1P91-A nrPDB Length = 269 Score = 30.5 bits (67), Expect = 0.95, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 20/45 (44%), Gaps = 3/45 (6%) Query: 46 NSIIDKAALRPTD---VVLEVGPGTGNMTVKLLEKAKKVVACELD 87 ++I+ + R D VL++G G G T + ++ LD Sbjct: 72 DAIVAQLRERLDDKATAVLDIGCGEGYYTHAFADALPEITTFGLD 116 >3LST-A nrPDB Length = 348 Score = 30.1 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 17/70 (24%), Positives = 28/70 (40%), Gaps = 1/70 (1%) Query: 48 IIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKL 107 + T V +VG G G + +L + + LD V R+ VA + Sbjct: 176 LARAGDFPATGTVADVGGGRGGFLLTVLREHPGLQGVLLDRAEV-VARHRLDAPDVAGRW 234 Query: 108 QVLVGDVLKT 117 +V+ GD L+ Sbjct: 235 KVVEGDFLRE 244 >2GLU-A nrPDB Length = 239 Score = 30.1 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 13/74 (17%), Positives = 25/74 (33%), Gaps = 1/74 (1%) Query: 48 IIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKL 107 +I A R VL++G G G+ + ++ + + +V Q V + Sbjct: 13 MIKTAECRAEHRVLDIGAGAGHTALAFSPYVQECIGVDATKEMVEVASSFAQEKGV-ENV 71 Query: 108 QVLVGDVLKTDLPF 121 + G P Sbjct: 72 RFQQGTAESLPFPD 85 >3OH9-A nrPDB Length = 289 Score = 30.1 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 24/119 (20%), Positives = 43/119 (36%), Gaps = 8/119 (6%) Query: 177 INTQLLARVDHLMKVGKNNFRPPPKVESSVVRI--EPKNPPPPINFQEWDGLVRITFVRK 234 + + LA++ L + N P V ++ R+ P ++ VR + Sbjct: 77 VAAECLAKMSRLFDLQCN----PQIVNGALGRLGAARPGLRLPGCVDAFEQGVRAILGQL 132 Query: 235 NKTLSAAFKSSAVQQLLEKNYRIHCSVHNIIIPEDFSIADKIQQILTSTGFSDKRARSM 293 AA ++ V QL + P+ + AD Q L + G KRA ++ Sbjct: 133 VSVAMAAKLTARVAQLYGERLDDFPEYICFPTPQRLAAAD--PQALKALGMPLKRAEAL 189 >5FA5-A nrPDB Length = 650 Score = 29.7 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 18/89 (20%), Positives = 36/89 (40%), Gaps = 7/89 (7%) Query: 44 IINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAK------KVVACELDPRLVAELHKR 97 +++ + ++ V++ +G G G + L AK K+ A E +P V L Sbjct: 358 LLDRVPEEEKDTNVQVLMVLGAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLEN- 416 Query: 98 VQGTPVASKLQVLVGDVLKTDLPFFDTCV 126 Q S++ V+ D+ + P + Sbjct: 417 WQFEEWGSQVTVVSSDMREWVAPEKADII 445 >4LWO-B nrPDB Length = 368 Score = 29.7 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 17/66 (25%), Positives = 31/66 (46%), Gaps = 2/66 (3%) Query: 46 NSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKK-VVACELDPRLVAELHKRVQGTPVA 104 I+++A VV++VG GTG +++ K V + E L V+ ++ Sbjct: 44 RKSIEQSASIEGKVVVDVGSGTGILSMWAARAGAKHVFSIEA-SSLSEFQIGVVEDNDLS 102 Query: 105 SKLQVL 110 +K+ VL Sbjct: 103 TKITVL 108 >4X3Q-A nrPDB Length = 355 Score = 29.7 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 14/70 (20%), Positives = 23/70 (32%), Gaps = 1/70 (1%) Query: 58 DVVLEVGPGTGNMTVKLLEKAKKVVACELDPR-LVAELHKRVQGTPVASKLQVLVGDVLK 116 VL+VG G V L + LD + K + + +++ D+ Sbjct: 172 HRVLDVGGGDAVNAVALARAHPSLRVTVLDRPGALEVARKTIAEAGLEERVRTHAADIFT 231 Query: 117 TDLPFFDTCV 126 P CV Sbjct: 232 DSYPAGHDCV 241 >5LV5-A nrPDB Length = 403 Score = 29.3 bits (64), Expect = 2.1, Method: Composition-based stats. Identities = 19/80 (23%), Positives = 35/80 (43%), Gaps = 2/80 (2%) Query: 48 IIDKAALRPTDVVLEVGPGTGNMTVKLLEKAK-KVVACELDPRLVAELHKRVQGTPVASK 106 I+ A VL+VG GTG +++ + +V A E + + + V+ + + Sbjct: 102 ILKNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEA-SAIWQQAREVVRLNGLEDR 160 Query: 107 LQVLVGDVLKTDLPFFDTCV 126 + VL G V +LP + Sbjct: 161 VHVLPGPVETVELPERVDAI 180 >1C3X-A nrPDB Length = 266 Score = 29.3 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 11/49 (22%), Positives = 17/49 (34%) Query: 38 ILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACEL 86 L + I + D+ L +G G G L E +V E+ Sbjct: 11 FLVARAAADHIAQATGVEGHDMALVLGSGWGGAAELLGEVVAEVPTHEI 59 >2PWY-A nrPDB Length = 258 Score = 28.9 bits (63), Expect = 2.6, Method: Composition-based stats. Identities = 11/39 (28%), Positives = 18/39 (46%) Query: 47 SIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACE 85 +++ L P VLE G G+G +T+ L + E Sbjct: 87 AMVTLLDLAPGMRVLEAGTGSGGLTLFLARAVGEKGLVE 125 >4KDR-A nrPDB Length = 223 Score = 28.9 bits (63), Expect = 2.7, Method: Composition-based stats. Identities = 12/47 (25%), Positives = 21/47 (44%) Query: 40 KNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACEL 86 NPL + I ++A VL+VG G G + + + V ++ Sbjct: 46 INPLRLGYIAERAGGLFGKKVLDVGCGGGILAESMAREGATVTGLDM 92 >4KDC-A nrPDB Length = 246 Score = 28.9 bits (63), Expect = 2.7, Method: Composition-based stats. Identities = 12/47 (25%), Positives = 21/47 (44%) Query: 40 KNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACEL 86 NPL + I ++A VL+VG G G + + + V ++ Sbjct: 46 INPLRLGYIAERAGGLFGKKVLDVGCGGGILAESMAREGATVTGLDM 92 >4FZV-A nrPDB Length = 359 Score = 28.9 bits (63), Expect = 2.7, Method: Composition-based stats. Identities = 15/52 (28%), Positives = 27/52 (51%), Gaps = 2/52 (3%) Query: 49 IDKAALRPTDVVLEVGPGTGNMTVKLLEK--AKKVVACELDPRLVAELHKRV 98 + L+P D+VL++ G T+ LL+ + + A +L P +A L K + Sbjct: 141 VLALGLQPGDIVLDLCAAPGGKTLALLQTGCCRNLAANDLSPSRIARLQKIL 192 >1P22-B nrPDB Length = 145 Score = 28.9 bits (63), Expect = 3.3, Method: Composition-based stats. Identities = 16/101 (15%), Positives = 32/101 (31%), Gaps = 5/101 (4%) Query: 197 RPPPKVESSVVR-----IEPKNPPPPINFQEWDGLVRITFVRKNKTLSAAFKSSAVQQLL 251 P P V +++++ PP + WD L A ++ LL Sbjct: 39 VPLPNVNAAILKKVIQWCTHHKDDPPDDIPVWDQEFLKVDQGTLFELILAANYLDIKGLL 98 Query: 252 EKNYRIHCSVHNIIIPEDFSIADKIQQILTSTGFSDKRARS 292 + + ++ PE+ I+ T + R + Sbjct: 99 DVTCKTVANMIKGKTPEEIRKTFNIKNDFTEEEEAQVRKEN 139 >5BSZ-A nrPDB Length = 250 Score = 28.5 bits (62), Expect = 3.5, Method: Composition-based stats. Identities = 19/80 (23%), Positives = 30/80 (37%), Gaps = 10/80 (12%) Query: 60 VLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVLKTDL 119 +L+V GTG L+E EL P + A +++ TP V D+ DL Sbjct: 51 LLDVACGTGEHLAHLVEHFPDAAGVELSPAMRAAAERKLTATP------VHQADMFDFDL 104 Query: 120 PFFDTCV----ANLPYQISS 135 V ++ Y + Sbjct: 105 GRVFDAVCCLTGSIAYAADT 124 >4C6Y-A nrPDB Length = 262 Score = 28.5 bits (62), Expect = 3.8, Method: Composition-based stats. Identities = 12/62 (19%), Positives = 25/62 (40%), Gaps = 3/62 (4%) Query: 44 IINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPV 103 + + I + +++LE G +T L +V + R EL++ + G P Sbjct: 96 LCEAAITYSDNTAANLLLEALGGPAALTAFLRSIGDEVTRLD---RWEPELNEALPGDPR 152 Query: 104 AS 105 + Sbjct: 153 DT 154 >5LP5-A nrPDB Length = 594 Score = 28.2 bits (61), Expect = 4.5, Method: Composition-based stats. Identities = 11/76 (14%), Positives = 24/76 (31%), Gaps = 8/76 (10%) Query: 75 LEKAKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVLKTDLPFFDTCVANLPYQIS 134 L++ + E+ + K + + +++K V +PY Sbjct: 79 LKQKDLLEKIEIIQKFFPNFSKETLLNNYQKENSLYNHNLIK--------VVGFIPYATM 130 Query: 135 SPFVFKLLLHRPFFRC 150 P KL+ + F Sbjct: 131 QPLYAKLIQTQGIFAL 146 >2PBF-A nrPDB Length = 227 Score = 27.4 bits (59), Expect = 7.6, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 30/76 (39%), Gaps = 11/76 (14%) Query: 54 LRPTDVVLEVGPGTGNMTV-------KLLEKAKKVVACELDPRLVAE-LHKRVQGTPVA- 104 L+P ++VG G+G +TV L K V+ E LV L + P Sbjct: 78 LKPGSRAIDVGSGSGYLTVCMAIKMNVLENKNSYVIGLERVKDLVNFSLENIKRDKPELL 137 Query: 105 --SKLQVLVGDVLKTD 118 +++ ++ + + Sbjct: 138 KIDNFKIIHKNIYQVN 153 >3PTW-A nrPDB Length = 336 Score = 27.0 bits (58), Expect = 10.0, Method: Composition-based stats. Identities = 12/52 (23%), Positives = 22/52 (42%), Gaps = 3/52 (5%) Query: 58 DVVLEVGPGTGNMTVKLLEKAKKVVACELD--PRLVAELHKRVQGTPVASKL 107 D +E+GPG ++ + + K V ++ L L K + +A L Sbjct: 268 DTFIEIGPGK-ALSGFVKKINKNVTVLNVEDLKSLEKTLSKLREMEVLAENL 318 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.129 0.320 Lambda K H 0.267 0.0396 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,385,124 Number of Sequences: 36641 Number of extensions: 366800 Number of successful extensions: 1482 Number of sequences better than 10.0: 130 Number of HSP's better than 10.0 without gapping: 108 Number of HSP's successfully gapped in prelim test: 85 Number of HSP's that attempted gapping in prelim test: 1281 Number of HSP's gapped (non-prelim): 203 length of query: 313 length of database: 10,336,785 effective HSP length: 97 effective length of query: 216 effective length of database: 6,782,608 effective search space: 1465043328 effective search space used: 1465043328 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 59 (27.4 bits)