BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9ULX3 (412 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6G5I-y nrPDB 858 0.0 2LCQ-A nrPDB 47 1e-05 6N9A-D nrPDB 32 0.60 5Z56-q nrPDB 29 3.1 2AAO-A nrPDB 29 4.4 4FOI-A nrPDB 28 5.3 3GGU-A nrPDB 28 8.0 >6G5I-y nrPDB Length = 412 Score = 858 bits (2217), Expect = 0.0, Method: Compositional matrix adjust. Identities = 412/412 (100%), Positives = 412/412 (100%) Query: 1 MAPVEHVVADAGAFLRHAALQDIGKNIYTIREVVTEIRDKATRRRLAVLPYELRFKEPLP 60 MAPVEHVVADAGAFLRHAALQDIGKNIYTIREVVTEIRDKATRRRLAVLPYELRFKEPLP Sbjct: 1 MAPVEHVVADAGAFLRHAALQDIGKNIYTIREVVTEIRDKATRRRLAVLPYELRFKEPLP 60 Query: 61 EYVRLVTEFSKKTGDYPSLSATDIQVLALTYQLEAEFVGVSHLKQEPQKVKVSSSIQHPE 120 EYVRLVTEFSKKTGDYPSLSATDIQVLALTYQLEAEFVGVSHLKQEPQKVKVSSSIQHPE Sbjct: 61 EYVRLVTEFSKKTGDYPSLSATDIQVLALTYQLEAEFVGVSHLKQEPQKVKVSSSIQHPE 120 Query: 121 TPLHISGFHLPYKPKPPQETEKGHSACEPENLEFSSFMFWRNPLPNIDHELQELLIDRGE 180 TPLHISGFHLPYKPKPPQETEKGHSACEPENLEFSSFMFWRNPLPNIDHELQELLIDRGE Sbjct: 121 TPLHISGFHLPYKPKPPQETEKGHSACEPENLEFSSFMFWRNPLPNIDHELQELLIDRGE 180 Query: 181 DVPSEEEEEEENGFEDRKDDSDDDGGGWITPSNIKQIQQELEQCDVPEDVRVGCLTTDFA 240 DVPSEEEEEEENGFEDRKDDSDDDGGGWITPSNIKQIQQELEQCDVPEDVRVGCLTTDFA Sbjct: 181 DVPSEEEEEEENGFEDRKDDSDDDGGGWITPSNIKQIQQELEQCDVPEDVRVGCLTTDFA 240 Query: 241 MQNVLLQMGLHVLAVNGMLIREARSYILRCHGCFKTTSDMSRVFCSHCGNKTLKKVSVTV 300 MQNVLLQMGLHVLAVNGMLIREARSYILRCHGCFKTTSDMSRVFCSHCGNKTLKKVSVTV Sbjct: 241 MQNVLLQMGLHVLAVNGMLIREARSYILRCHGCFKTTSDMSRVFCSHCGNKTLKKVSVTV 300 Query: 301 SDDGTLHMHFSRNPKVLNPRGLRYSLPTPKGGKYAINPHLTEDQRFPQLRLSQKARQKTN 360 SDDGTLHMHFSRNPKVLNPRGLRYSLPTPKGGKYAINPHLTEDQRFPQLRLSQKARQKTN Sbjct: 301 SDDGTLHMHFSRNPKVLNPRGLRYSLPTPKGGKYAINPHLTEDQRFPQLRLSQKARQKTN 360 Query: 361 VFAPDYIAGVSPFVENDISSRSATLQVRDSTLGAGRRRLNPNASRKKFVKKR 412 VFAPDYIAGVSPFVENDISSRSATLQVRDSTLGAGRRRLNPNASRKKFVKKR Sbjct: 361 VFAPDYIAGVSPFVENDISSRSATLQVRDSTLGAGRRRLNPNASRKKFVKKR 412 >2LCQ-A nrPDB Length = 165 Score = 47.4 bits (111), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 29/93 (31%), Positives = 51/93 (54%), Gaps = 7/93 (7%) Query: 7 VVADAGAFLRHAALQDIGKNIYTIREVVTEIRDKATRRRLAVL--PYELRFKEPLPEYVR 64 +V D+ F++ ++ YT VV EI+D+ ++ L L +++ EP E + Sbjct: 13 LVLDSSVFIQGIDIEG-----YTTPSVVEEIKDRESKIFLESLISAGKVKIAEPSKESID 67 Query: 65 LVTEFSKKTGDYPSLSATDIQVLALTYQLEAEF 97 + + +K+TG+ LS DI+VLAL Y+L+ E Sbjct: 68 RIIQVAKETGEVNELSKADIEVLALAYELKGEI 100 >6N9A-D nrPDB Length = 330 Score = 31.6 bits (70), Expect = 0.60, Method: Compositional matrix adjust. Identities = 36/125 (28%), Positives = 58/125 (46%), Gaps = 17/125 (13%) Query: 19 ALQDIGKNI---YTIREVVTEIRDK--------ATRRRLAVLPYELR--FKEPLPEYVRL 65 A+ D GKN+ +T+ ++ E+ K A R L LP L+ F++ PE V + Sbjct: 19 AVLDDGKNVVVNFTVSQI--EVHQKFGGVVPEVAARHHLKNLPILLKKAFEKVPPETVDV 76 Query: 66 VTEFSKKTGDYPSLSATDIQVLALTYQLEAEFVGVSHLKQEPQKVKVSS-SIQHPETPLH 124 V + G +L L LE FVGV+H++ Q V +++ ++ P L Sbjct: 77 VAA-TYGPGLIGALLVGLSAAKGLAISLEKPFVGVNHVEAHVQAVFLANPDLKPPLVVLM 135 Query: 125 ISGFH 129 +SG H Sbjct: 136 VSGGH 140 >5Z56-q nrPDB Length = 504 Score = 29.3 bits (64), Expect = 3.1, Method: Compositional matrix adjust. Identities = 17/69 (24%), Positives = 35/69 (50%), Gaps = 6/69 (8%) Query: 22 DIGKNIYTIREVVTEIRDKAT------RRRLAVLPYELRFKEPLPEYVRLVTEFSKKTGD 75 D+G+ + E++ +++DKAT ++R +P EL E L +Y ++ + + Sbjct: 161 DLGELVGMTPEIIQKLQDKATVLTTERKKRGKTVPEELVKPEELSKYRQVASHVGLHSAS 220 Query: 76 YPSLSATDI 84 P + A D+ Sbjct: 221 IPGILALDL 229 >2AAO-A nrPDB Length = 166 Score = 28.9 bits (63), Expect = 4.4, Method: Compositional matrix adjust. Identities = 18/42 (42%), Positives = 23/42 (54%), Gaps = 4/42 (9%) Query: 202 DDDGGGWITPSNIKQIQQELEQCDVPEDVRVGCLTTDFAMQN 243 D DG G+ITP ++QQ E+ V EDVR+ L D N Sbjct: 109 DKDGSGYITPD---ELQQACEEFGV-EDVRIEELMRDVDQDN 146 >4FOI-A nrPDB Length = 917 Score = 28.5 bits (62), Expect = 5.3, Method: Compositional matrix adjust. Identities = 30/108 (27%), Positives = 48/108 (44%), Gaps = 19/108 (17%) Query: 241 MQNVLLQMGLHVLAVNGMLIREARSYILR-----CHGCFKTTSDMSRVFCSHCGNKTLKK 295 ++ +L Q+GL+ + +L++ + R C D R N+ L + Sbjct: 800 VRAILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIR------ENRGLDR 853 Query: 296 VSVTVSDDGT---LHMHFSR----NPKVLNPR-GLRYSLPTPKGGKYA 335 ++VTV DGT LH HFSR K L+P+ + + L GK A Sbjct: 854 LNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGA 901 >3GGU-A nrPDB Length = 99 Score = 28.1 bits (61), Expect = 8.0, Method: Composition-based stats. Identities = 25/93 (26%), Positives = 42/93 (45%), Gaps = 5/93 (5%) Query: 159 FWRNPLPN--IDHELQELLIDRGEDVPSEEEEEEENGFEDRKDDSDDDGGGWITPSNIKQ 216 W+ P+ I+ +L+E L+D G D EE ++ R GG++ Q Sbjct: 5 LWQRPIVTVKIEGQLKEALLDTGADDTVFEELTLSGRWKPRLIGGI---GGFVRVRQYDQ 61 Query: 217 IQQELEQCDVPEDVRVGCLTTDFAMQNVLLQMG 249 + E+ V + V VG T+ +NV+ Q+G Sbjct: 62 VPIEICGHKVIDTVLVGPTPTNVIGRNVMTQLG 94 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6G5I-y nrPDB 862 0.0 2LCQ-A nrPDB 128 4e-30 Sequences not found previously or not previously below threshold: 3CRV-A nrPDB 32 0.36 3HAI-A nrPDB 31 1.0 1UZR-A nrPDB 31 1.2 2AAO-A nrPDB 31 1.2 6N9A-D nrPDB 30 1.5 3LLL-A nrPDB 30 1.7 4FOI-A nrPDB 30 2.5 5Z56-q nrPDB 29 4.2 3GGU-A nrPDB 28 5.4 CONVERGED! >6G5I-y nrPDB Length = 412 Score = 862 bits (2228), Expect = 0.0, Method: Composition-based stats. Identities = 412/412 (100%), Positives = 412/412 (100%) Query: 1 MAPVEHVVADAGAFLRHAALQDIGKNIYTIREVVTEIRDKATRRRLAVLPYELRFKEPLP 60 MAPVEHVVADAGAFLRHAALQDIGKNIYTIREVVTEIRDKATRRRLAVLPYELRFKEPLP Sbjct: 1 MAPVEHVVADAGAFLRHAALQDIGKNIYTIREVVTEIRDKATRRRLAVLPYELRFKEPLP 60 Query: 61 EYVRLVTEFSKKTGDYPSLSATDIQVLALTYQLEAEFVGVSHLKQEPQKVKVSSSIQHPE 120 EYVRLVTEFSKKTGDYPSLSATDIQVLALTYQLEAEFVGVSHLKQEPQKVKVSSSIQHPE Sbjct: 61 EYVRLVTEFSKKTGDYPSLSATDIQVLALTYQLEAEFVGVSHLKQEPQKVKVSSSIQHPE 120 Query: 121 TPLHISGFHLPYKPKPPQETEKGHSACEPENLEFSSFMFWRNPLPNIDHELQELLIDRGE 180 TPLHISGFHLPYKPKPPQETEKGHSACEPENLEFSSFMFWRNPLPNIDHELQELLIDRGE Sbjct: 121 TPLHISGFHLPYKPKPPQETEKGHSACEPENLEFSSFMFWRNPLPNIDHELQELLIDRGE 180 Query: 181 DVPSEEEEEEENGFEDRKDDSDDDGGGWITPSNIKQIQQELEQCDVPEDVRVGCLTTDFA 240 DVPSEEEEEEENGFEDRKDDSDDDGGGWITPSNIKQIQQELEQCDVPEDVRVGCLTTDFA Sbjct: 181 DVPSEEEEEEENGFEDRKDDSDDDGGGWITPSNIKQIQQELEQCDVPEDVRVGCLTTDFA 240 Query: 241 MQNVLLQMGLHVLAVNGMLIREARSYILRCHGCFKTTSDMSRVFCSHCGNKTLKKVSVTV 300 MQNVLLQMGLHVLAVNGMLIREARSYILRCHGCFKTTSDMSRVFCSHCGNKTLKKVSVTV Sbjct: 241 MQNVLLQMGLHVLAVNGMLIREARSYILRCHGCFKTTSDMSRVFCSHCGNKTLKKVSVTV 300 Query: 301 SDDGTLHMHFSRNPKVLNPRGLRYSLPTPKGGKYAINPHLTEDQRFPQLRLSQKARQKTN 360 SDDGTLHMHFSRNPKVLNPRGLRYSLPTPKGGKYAINPHLTEDQRFPQLRLSQKARQKTN Sbjct: 301 SDDGTLHMHFSRNPKVLNPRGLRYSLPTPKGGKYAINPHLTEDQRFPQLRLSQKARQKTN 360 Query: 361 VFAPDYIAGVSPFVENDISSRSATLQVRDSTLGAGRRRLNPNASRKKFVKKR 412 VFAPDYIAGVSPFVENDISSRSATLQVRDSTLGAGRRRLNPNASRKKFVKKR Sbjct: 361 VFAPDYIAGVSPFVENDISSRSATLQVRDSTLGAGRRRLNPNASRKKFVKKR 412 >2LCQ-A nrPDB Length = 165 Score = 128 bits (322), Expect = 4e-30, Method: Composition-based stats. Identities = 29/93 (31%), Positives = 51/93 (54%), Gaps = 7/93 (7%) Query: 7 VVADAGAFLRHAALQDIGKNIYTIREVVTEIRDKATRRRLAVL--PYELRFKEPLPEYVR 64 +V D+ F++ ++ YT VV EI+D+ ++ L L +++ EP E + Sbjct: 13 LVLDSSVFIQGIDIEG-----YTTPSVVEEIKDRESKIFLESLISAGKVKIAEPSKESID 67 Query: 65 LVTEFSKKTGDYPSLSATDIQVLALTYQLEAEF 97 + + +K+TG+ LS DI+VLAL Y+L+ E Sbjct: 68 RIIQVAKETGEVNELSKADIEVLALAYELKGEI 100 >3CRV-A nrPDB Length = 551 Score = 32.3 bits (72), Expect = 0.36, Method: Composition-based stats. Identities = 18/75 (24%), Positives = 37/75 (49%), Gaps = 9/75 (12%) Query: 19 ALQDIGKNIYTIREVVTEIRDKATRRRLAVLPYELR-FKEPLPEYVRLVTEFSKKTGDYP 77 L++ + TI+ + + + + +RR L+ L +LR P +Y+ K + P Sbjct: 190 ELEERSLSEITIQMAIKQSKSEESRRILSKLLNQLREVVLPDEKYI--------KVENVP 241 Query: 78 SLSATDIQVLALTYQ 92 LS ++++LA Y+ Sbjct: 242 KLSKEELEILADDYE 256 >3HAI-A nrPDB Length = 308 Score = 30.8 bits (68), Expect = 1.0, Method: Composition-based stats. Identities = 40/152 (26%), Positives = 65/152 (42%), Gaps = 20/152 (13%) Query: 120 ETPLHISGFHLPYKP--KPPQETEKG----HSACEPENLEFSSFMFWRNPLPNIDHELQE 173 ET GF KP K +E E H AC+ E L + M + ++ E Q+ Sbjct: 131 ETKEAEDGFRKAQKPWAKKMKELEAAKKAYHLACKEEKLAMTREMNSKTE-QSVTPEQQK 189 Query: 174 LLIDRGEDVPSEEEEEEENGFEDRKDDSDDDGGGWITPSNIKQIQQELEQCDVPEDVRVG 233 L D+ + + ++ +E +E +D G TP ++ ++Q EQC E+ R+ Sbjct: 190 KLQDKVDKCKQDVQKTQEK-YEKVLEDV-----GKTTPQYMENMEQVFEQCQQFEEKRL- 242 Query: 234 CLTTDFAMQNVLLQMGLHV-LAVNGMLIREAR 264 ++ VLL + H+ LA N I R Sbjct: 243 -----VFLKEVLLDIKRHLNLAENSSYIHVYR 269 >1UZR-A nrPDB Length = 296 Score = 30.8 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 18/40 (45%), Positives = 25/40 (62%), Gaps = 2/40 (5%) Query: 92 QLEAEFVGVSHLKQEPQKVKVSSSIQHPETPLHISGFHLP 131 Q +AE V S+ EP K KV+S++ E+ L SGF+LP Sbjct: 137 QRKAEIVLQSYRGDEPLKRKVASTLL--ESFLFYSGFYLP 174 >2AAO-A nrPDB Length = 166 Score = 30.8 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 18/42 (42%), Positives = 23/42 (54%), Gaps = 4/42 (9%) Query: 202 DDDGGGWITPSNIKQIQQELEQCDVPEDVRVGCLTTDFAMQN 243 D DG G+ITP ++QQ E+ V EDVR+ L D N Sbjct: 109 DKDGSGYITPD---ELQQACEEFGV-EDVRIEELMRDVDQDN 146 >6N9A-D nrPDB Length = 330 Score = 30.4 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 31/100 (31%), Positives = 46/100 (46%), Gaps = 7/100 (7%) Query: 33 VVTEIRDKATRRRLAVLPYELR--FKEPLPEYVRLVTEFSKKTGDYPSLSATDIQVLALT 90 VV E+ A R L LP L+ F++ PE V V + G +L L Sbjct: 45 VVPEV---AARHHLKNLPILLKKAFEKVPPETVD-VVAATYGPGLIGALLVGLSAAKGLA 100 Query: 91 YQLEAEFVGVSHLKQEPQKVKVSS-SIQHPETPLHISGFH 129 LE FVGV+H++ Q V +++ ++ P L +SG H Sbjct: 101 ISLEKPFVGVNHVEAHVQAVFLANPDLKPPLVVLMVSGGH 140 >3LLL-A nrPDB Length = 287 Score = 30.0 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 45/198 (22%), Positives = 82/198 (41%), Gaps = 25/198 (12%) Query: 52 ELRFKEPLPEYVRLVTEFSKKTGDYPSLSATDIQVLALT---YQLEAEFVGVSHLKQEPQ 108 E + + L E+ R + +K Y ++ I V++ +L E V S + ++ + Sbjct: 37 EKAYAQQLTEWARRWRQLVEKGPQYGTVEKAWIAVMSEAERVSELHLE-VKASLMNEDFE 95 Query: 109 KVK-VSSSIQHP-------ETPLHISGFHLPYKP--KPPQETEKG----HSACEPENLEF 154 K+K H ET GF KP K +E E H+AC+ E L Sbjct: 96 KIKNWQKEAFHKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAHHTACKEEKLAI 155 Query: 155 SSFMFWRNPLPNIDHELQELLIDRGEDVPSEEEEEEENGFEDRKDDSDDDGGGWITPSNI 214 S + P+++ E + L D+ E ++ + ++ +E + D TP + Sbjct: 156 SREANSKAD-PSLNPEQLKKLQDKIEKC-KQDVLKTKDKYEKSLKELDQ-----TTPQYM 208 Query: 215 KQIQQELEQCDVPEDVRV 232 + ++Q EQC E+ R+ Sbjct: 209 ENMEQVFEQCQQFEEKRL 226 >4FOI-A nrPDB Length = 917 Score = 29.7 bits (65), Expect = 2.5, Method: Composition-based stats. Identities = 23/80 (28%), Positives = 37/80 (46%), Gaps = 14/80 (17%) Query: 241 MQNVLLQMGLHVLAVNGMLIREARSYILR-----CHGCFKTTSDMSRVFCSHCGNKTLKK 295 ++ +L Q+GL+ + +L++ + R C D R N+ L + Sbjct: 800 VRAILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIR------ENRGLDR 853 Query: 296 VSVTVSDDGT---LHMHFSR 312 ++VTV DGT LH HFSR Sbjct: 854 LNVTVGVDGTLYKLHPHFSR 873 >5Z56-q nrPDB Length = 504 Score = 28.9 bits (63), Expect = 4.2, Method: Composition-based stats. Identities = 17/69 (24%), Positives = 35/69 (50%), Gaps = 6/69 (8%) Query: 22 DIGKNIYTIREVVTEIRDKAT------RRRLAVLPYELRFKEPLPEYVRLVTEFSKKTGD 75 D+G+ + E++ +++DKAT ++R +P EL E L +Y ++ + + Sbjct: 161 DLGELVGMTPEIIQKLQDKATVLTTERKKRGKTVPEELVKPEELSKYRQVASHVGLHSAS 220 Query: 76 YPSLSATDI 84 P + A D+ Sbjct: 221 IPGILALDL 229 >3GGU-A nrPDB Length = 99 Score = 28.5 bits (62), Expect = 5.4, Method: Composition-based stats. Identities = 25/93 (26%), Positives = 42/93 (45%), Gaps = 5/93 (5%) Query: 159 FWRNPLPN--IDHELQELLIDRGEDVPSEEEEEEENGFEDRKDDSDDDGGGWITPSNIKQ 216 W+ P+ I+ +L+E L+D G D EE ++ R GG++ Q Sbjct: 5 LWQRPIVTVKIEGQLKEALLDTGADDTVFEELTLSGRWKPRLIGGI---GGFVRVRQYDQ 61 Query: 217 IQQELEQCDVPEDVRVGCLTTDFAMQNVLLQMG 249 + E+ V + V VG T+ +NV+ Q+G Sbjct: 62 VPIEICGHKVIDTVLVGPTPTNVIGRNVMTQLG 94 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.315 0.134 0.382 Lambda K H 0.267 0.0412 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,806,674 Number of Sequences: 36641 Number of extensions: 727717 Number of successful extensions: 2784 Number of sequences better than 10.0: 34 Number of HSP's better than 10.0 without gapping: 32 Number of HSP's successfully gapped in prelim test: 36 Number of HSP's that attempted gapping in prelim test: 2551 Number of HSP's gapped (non-prelim): 203 length of query: 412 length of database: 10,336,785 effective HSP length: 99 effective length of query: 313 effective length of database: 6,709,326 effective search space: 2100019038 effective search space used: 2100019038 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.5 bits) S2: 60 (27.7 bits)