BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9UKU7 (415 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1RX0-A nrPDB 816 0.0 5OL2-C nrPDB 302 2e-82 5LNX-A nrPDB 281 3e-76 4L1F-A nrPDB 280 9e-76 1UKW-A nrPDB 273 1e-73 4U83-A nrPDB 273 1e-73 1JQI-A nrPDB 265 3e-71 6FAH-C nrPDB 259 2e-69 2VIG-A nrPDB 254 6e-68 4N5F-A nrPDB 251 3e-67 4M9A-A nrPDB 250 9e-67 1BUC-A nrPDB 244 5e-65 3MDE-A nrPDB 244 7e-65 3PFD-A nrPDB 243 2e-64 2A1T-A nrPDB 240 9e-64 2DVL-A nrPDB 232 2e-61 2Z1Q-A nrPDB 231 3e-61 2PG0-A nrPDB 230 1e-60 2JIF-A nrPDB 226 2e-59 3OWA-A nrPDB 224 4e-59 4O5M-A nrPDB 224 4e-59 4IV6-A nrPDB 223 1e-58 2CX9-A nrPDB 222 3e-58 3R7K-A nrPDB 221 5e-58 1IVH-A nrPDB 220 1e-57 3NF4-A nrPDB 215 2e-56 4KTO-A nrPDB 209 2e-54 3P4T-A nrPDB 204 5e-53 4IRN-A nrPDB 197 5e-51 3B96-A nrPDB 191 5e-49 5AHS-A nrPDB 184 5e-47 3MPI-A nrPDB 184 5e-47 5JSC-A nrPDB 165 3e-41 5IDU-A nrPDB 162 2e-40 6CY8-B nrPDB 157 5e-39 6ES9-A nrPDB 156 1e-38 3GNC-A nrPDB 151 6e-37 5ZW7-A nrPDB 147 6e-36 2EBA-A nrPDB 135 3e-32 3SF6-A nrPDB 125 3e-29 4W9U-A nrPDB 125 4e-29 3SWO-A nrPDB 123 1e-28 1SIR-A nrPDB 120 7e-28 2IX5-A nrPDB 114 1e-25 1R2J-A nrPDB 104 8e-23 4HR3-A nrPDB 99 4e-21 4X28-A nrPDB 99 4e-21 4RM7-A nrPDB 92 5e-19 2WBI-A nrPDB 91 9e-19 5EZ3-A nrPDB 77 1e-14 3U33-A nrPDB 76 2e-14 4Y9J-A nrPDB 74 8e-14 4XVX-A nrPDB 61 1e-09 5GJ7-A nrPDB 55 5e-08 3MXL-A nrPDB 54 9e-08 4ZYJ-A nrPDB 54 2e-07 3M9V-A nrPDB 52 3e-07 2C12-A nrPDB 49 3e-06 5YS9-A nrPDB 49 3e-06 3MKH-A nrPDB 47 2e-05 4X28-D nrPDB 45 5e-05 4JEK-A nrPDB 45 7e-05 1W07-A nrPDB 44 2e-04 5Y9D-A nrPDB 38 0.007 5XDD-A nrPDB 35 0.046 1IS2-A nrPDB 35 0.063 3DFG-A nrPDB 30 2.5 6A7I-A nrPDB 29 3.1 4J3X-A nrPDB 29 4.2 5A31-O nrPDB 28 6.4 >1RX0-A nrPDB Length = 393 Score = 816 bits (2109), Expect = 0.0, Method: Compositional matrix adjust. Identities = 392/393 (99%), Positives = 393/393 (100%) Query: 23 LVQTGHRSLTSCIDPSMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAA 82 +VQTGHRSLTSCIDPSMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAA Sbjct: 1 MVQTGHRSLTSCIDPSMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAA 60 Query: 83 QLGFGGVYIQTDVGGSGLSRLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSFGNEEQR 142 QLGFGGVYIQTDVGGSGLSRLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSFGNEEQR Sbjct: 61 QLGFGGVYIQTDVGGSGLSRLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSFGNEEQR 120 Query: 143 HKFCPPLCTMEKFASYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYV 202 HKFCPPLCTMEKFASYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYV Sbjct: 121 HKFCPPLCTMEKFASYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYV 180 Query: 203 VMCRTGGPGPKGISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSE 262 VMCRTGGPGPKGISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSE Sbjct: 181 VMCRTGGPGPKGISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSE 240 Query: 263 GQGFLIAVRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADM 322 GQGFLIAVRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADM Sbjct: 241 GQGFLIAVRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADM 300 Query: 323 ATRLVAARLMVRNAAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDY 382 ATRLVAARLMVRNAAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDY Sbjct: 301 ATRLVAARLMVRNAAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDY 360 Query: 383 AVQQYVRDSRVHQILEGSNEVMRILISRSLLQE 415 AVQQYVRDSRVHQILEGSNEVMRILISRSLLQE Sbjct: 361 AVQQYVRDSRVHQILEGSNEVMRILISRSLLQE 393 >5OL2-C nrPDB Length = 378 Score = 302 bits (774), Expect = 2e-82, Method: Compositional matrix adjust. Identities = 163/379 (43%), Positives = 231/379 (60%), Gaps = 4/379 (1%) Query: 39 MGLNEEQKEFQKVAF-DFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGG 97 M LN ++ + K + FA E+ P E D++E FP + + K A+ G G+ + GG Sbjct: 1 MDLNSKKYQMLKELYVSFAENEVKPLATELDEEERFPYETVEKMAKAGMMGIPYPKEYGG 60 Query: 98 SGLSRLDTSVIFEALATGCTSTTAYISIH-NMCAWMIDSFGNEEQRHKFCPPLCTMEKFA 156 G + + E L+ C +T +S H ++ +W I +GNEEQ+ KF PL + EK Sbjct: 61 EGGDTVGYIMAVEELSRVCGTTGVILSAHTSLGSWPIYQYGNEEQKQKFLRPLASGEKLG 120 Query: 157 SYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTG-GPGPKGI 215 ++ LTEP +G+DA+ T+A GD YILNGSK FI+ A DIYVVM T G KGI Sbjct: 121 AFGLTEPNAGTDASGQQTTAVLDGDEYILNGSKIFITNAIAGDIYVVMAMTDKSKGNKGI 180 Query: 216 SCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNG 275 S +VEKGTPG SFG KEKK+G T +IFEDC +P N +G EGQGF IA+ L+G Sbjct: 181 SAFIVEKGTPGFSFGVKEKKMGIRGSATSELIFEDCRIPKENLLGKEGQGFKIAMSTLDG 240 Query: 276 GRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRN 335 GRI IA+ +LG A ++ T ++ R QFG PL+ Q QF LADM ++ AAR +V Sbjct: 241 GRIGIAAQALGLAQGALDETVKYVKERVQFGRPLSKFQNTQFQLADMEVKVQAARHLVYQ 300 Query: 336 AAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQ 395 AA+ + V +MAKLFA + + +A+Q+HGGYGY +DY V++ +RD+++ + Sbjct: 301 AAINKDLGKPYGVE-AAMAKLFAAETAMEVTTKAVQLHGGYGYTRDYPVERMMRDAKITE 359 Query: 396 ILEGSNEVMRILISRSLLQ 414 I EG++EV R++IS LL+ Sbjct: 360 IYEGTSEVQRMVISGKLLK 378 >5LNX-A nrPDB Length = 379 Score = 281 bits (720), Expect = 3e-76, Method: Compositional matrix adjust. Identities = 154/377 (40%), Positives = 224/377 (59%), Gaps = 3/377 (0%) Query: 39 MGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGS 98 M + +EQ +K+ DFA +E+AP ++ + FP +++K + G G+ + GG+ Sbjct: 1 MHVTQEQVMMRKMVRDFARKEIAPAAEIMEKTDEFPFQLIKKMGKHGLMGIPVPEQYGGA 60 Query: 99 GLSRLDTSVIFEALATGCTSTTAYISIHNMCAWM-IDSFGNEEQRHKFCPPLCTMEKFAS 157 G + + ++ + +S+H I FGNEEQ+ K+ P L + + + Sbjct: 61 GADVVSYILAIHEISRISAAVGVILSVHTSVGTNPILYFGNEEQKMKYIPNLASGDHLGA 120 Query: 158 YCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTG-GPGPKGIS 216 + LTEP SGSDA SL T+A K+ Y+LNGSK FI+ G +DIY+ T G GIS Sbjct: 121 FALTEPHSGSDAGSLRTTAIKKNGKYLLNGSKIFITNGGAADIYITFALTAPDQGRHGIS 180 Query: 217 CIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGG 276 +VEK TPG + GKKE+K+G T +IF++ VP AN +G EG GF IA+ LN G Sbjct: 181 AFIVEKNTPGFTVGKKERKLGLYGSNTTELIFDNAEVPEANLLGKEGDGFHIAMANLNVG 240 Query: 277 RINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNA 336 RI IA+ +LG A A++ D+ R QFG P+A+NQ + F LADMATR AAR +V +A Sbjct: 241 RIGIAAQALGIAEAALEHAVDYAKQRVQFGRPIAANQGISFKLADMATRAEAARHLVYHA 300 Query: 337 AVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQI 396 A L + SMAK FA+D A+Q++GGYGY+KDY V++ +RD++V QI Sbjct: 301 A-DLHNRGLNCGKEASMAKQFASDAAVKAALDAVQIYGGYGYMKDYPVERLLRDAKVTQI 359 Query: 397 LEGSNEVMRILISRSLL 413 EG+NE+ R++IS+ LL Sbjct: 360 YEGTNEIQRLIISKYLL 376 >4L1F-A nrPDB Length = 383 Score = 280 bits (716), Expect = 9e-76, Method: Compositional matrix adjust. Identities = 151/377 (40%), Positives = 230/377 (61%), Gaps = 3/377 (0%) Query: 41 LNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGL 100 L E+Q+ + +A +FA + +AP + E D+ ++ ++ K + GF G+ + GG GL Sbjct: 5 LTEDQQMIKDMAAEFAEKFLAPTVEERDKAHIWDRKLIDKMGEAGFCGICFPEEYGGMGL 64 Query: 101 SRLDTSVIFEALATGCTSTTAYISIH-NMCAWMIDSFGNEEQRHKFCPPLCTMEKFASYC 159 L + E L+ T +S + ++CA I FG EEQ+ K+ P+ ++ Sbjct: 65 DVLSYILAVEELSKVDDGTGITLSANVSLCATPIYMFGTEEQKQKYLAPIAEGTHVGAFG 124 Query: 160 LTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTG-GPGPKGISCI 218 LTEP +G+DA++ T+A +GD YILNGSK FI+ E+D YVV T G GIS Sbjct: 125 LTEPSAGTDASAQQTTAVLKGDKYILNGSKIFITNGKEADTYVVFAMTDKSQGVHGISAF 184 Query: 219 VVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGGRI 278 ++EKG PG FGK E K+G ++ T +IFEDC VP N +G EG+GF IA+ L+GGRI Sbjct: 185 ILEKGMPGFRFGKIEDKMGGHTSITAELIFEDCEVPKENLLGKEGEGFKIAMETLDGGRI 244 Query: 279 NIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNAAV 338 +A+ +LG A ++ + R+QFG ++ Q LQF +ADMAT++ AAR +V +AA+ Sbjct: 245 GVAAQALGIAEGALAAAVKYSKEREQFGRSISKFQALQFMMADMATKIEAARYLVYHAAM 304 Query: 339 ALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQILE 398 L+ E K +MAK FA+D + A+Q+ GGYGY DY ++Y+R++++ QI E Sbjct: 305 -LKNEGKPYSEAAAMAKCFASDVAMEVTTDAVQIFGGYGYTVDYPAERYMRNAKITQIYE 363 Query: 399 GSNEVMRILISRSLLQE 415 G+N+VMRI+ SR+LL++ Sbjct: 364 GTNQVMRIVTSRALLRD 380 >1UKW-A nrPDB Length = 379 Score = 273 bits (697), Expect = 1e-73, Method: Compositional matrix adjust. Identities = 147/375 (39%), Positives = 224/375 (59%), Gaps = 4/375 (1%) Query: 41 LNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGL 100 L EEQ++ Q +A FA + P E+D+KE P V+ K ++G I + GG GL Sbjct: 5 LTEEQRQLQALARRFAKEVILPVAQEYDEKEEVPWPVIEKLHEVGLLNAIIPEEYGGMGL 64 Query: 101 SRLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSFGNEEQRHKFCPPLCTMEKFASYCL 160 LD ++ E LA C ++ + G EEQ+ +F PL A++ L Sbjct: 65 KMLDEVIVGEELAYACMGIYTIPMASDLGITPVLLAGTEEQKERFLRPLTEKPALAAFAL 124 Query: 161 TEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGGPG--PKGISCI 218 +EPG+GSDAA+L T A +QGDHY+LNG+K +IS GE++ +VV+ T P KG+ + Sbjct: 125 SEPGNGSDAAALKTRAIRQGDHYVLNGTKMWISNGGEAE-WVVVFATVNPELRHKGVVAL 183 Query: 219 VVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGGRI 278 VVE+GTPG K K+G + T ++FED VPV NR+G EG+GF IA++ LN RI Sbjct: 184 VVERGTPGFKAIKIHGKMGQRASGTYELVFEDVKVPVENRLGEEGEGFKIAMQTLNKTRI 243 Query: 279 NIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNAAV 338 +A+ S+G A ++ R + R+ FGEP+A+ Q +QF L DM + AR+ AA Sbjct: 244 PVAAGSVGVARRALDEARKYAKEREAFGEPIANFQAIQFKLVDMLIGIETARMYTYYAAW 303 Query: 339 ALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQILE 398 + A A ++AK +A++ F NQA+Q+HGGYGY++++ V++ +RD +++QI E Sbjct: 304 LADQGLPHAHA-SAIAKAYASEIAFEAANQAIQIHGGYGYVREFPVEKLLRDVKLNQIYE 362 Query: 399 GSNEVMRILISRSLL 413 G+NE+ R++I+R +L Sbjct: 363 GTNEIQRLIIARHIL 377 >4U83-A nrPDB Length = 382 Score = 273 bits (697), Expect = 1e-73, Method: Compositional matrix adjust. Identities = 151/376 (40%), Positives = 225/376 (59%), Gaps = 3/376 (0%) Query: 39 MGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGS 98 M L + Q++ ++ A DFA +AP A D++ FP + + LGF G+ + GGS Sbjct: 8 MLLTDTQEQIREAARDFAQERLAPGAAARDREHAFPRAELTEMGALGFLGMLAPEEWGGS 67 Query: 99 GLSRLDTSVIFEALATGCTSTTAYISIHNMCAWM-IDSFGNEEQRHKFCPPLCTMEKFAS 157 L + ++ E +A G + + +S+H+ M I FG E+Q+ +F P + E Sbjct: 68 DLDMVAYALALEEIAAGDGACSTIVSVHSSVGCMPILRFGTEDQKRRFLPKMACGEWIGG 127 Query: 158 YCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTG-GPGPKGIS 216 + LTEP +GSDA++L T A+ GDHY+++GSK FI+ ++ +V T G KGIS Sbjct: 128 FALTEPQAGSDASALKTRARLDGDHYVIDGSKQFITSGKNGNVVIVFAVTDPAAGKKGIS 187 Query: 217 CIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGG 276 +V TPG E K+G +S T A+ F + VPV NR+G+EG+G+ IA+ L GG Sbjct: 188 AFIVPTDTPGYEVMSVEHKLGQHSSDTCALGFTNMRVPVENRLGAEGEGYKIALANLEGG 247 Query: 277 RINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNA 336 RI IA+ ++G A A+ RD+ R FG+P+ +Q + F LADMATR+ AR MV +A Sbjct: 248 RIGIAAQAVGMARAAFEAARDYARERITFGKPIIEHQAVAFRLADMATRIETARQMVLHA 307 Query: 337 AVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQI 396 A AL+E K + SMAKL A++ +C+ A+Q+HGGYGYL DY V++ RD RV QI Sbjct: 308 A-ALREAGKPCLTEASMAKLVASEMAEQVCSAAIQIHGGYGYLADYPVERIYRDVRVCQI 366 Query: 397 LEGSNEVMRILISRSL 412 EG+++V R++I+R L Sbjct: 367 YEGTSDVQRLVIARGL 382 >1JQI-A nrPDB Length = 388 Score = 265 bits (676), Expect = 3e-71, Method: Compositional matrix adjust. Identities = 144/379 (37%), Positives = 229/379 (60%), Gaps = 3/379 (0%) Query: 38 SMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGG 97 S+ L E + ++ DFA +E+ P A+ D++ LFP ++K +LG + + ++ G Sbjct: 7 SVELPETHQMLRQTCRDFAEKELVPIAAQLDKEHLFPTSQVKKMGELGLLAMDVPEELSG 66 Query: 98 SGLSRLDTSVIFEALATGCTSTTAYISIHN-MCAWMIDSFGNEEQRHKFCPPLCTMEKFA 156 +GL L S+ E ++ GC ST +S++N + I FG+ +Q+ ++ P +K Sbjct: 67 AGLDYLAYSIALEEISRGCASTGVIMSVNNSLYLGPILKFGSSQQKQQWITPFTNGDKIG 126 Query: 157 SYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTG-GPGPKGI 215 + L+EPG+GSDA + T+A+++GD ++LNG+KA+I+ + E+ VV T KGI Sbjct: 127 CFALSEPGNGSDAGAASTTAREEGDSWVLNGTKAWITNSWEASATVVFASTDRSRQNKGI 186 Query: 216 SCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNG 275 S +V TPGL+ GKKE K+G + T +IFEDC +P N +G G GF IA++ L+ Sbjct: 187 SAFLVPMPTPGLTLGKKEDKLGIRASSTANLIFEDCRIPKENLLGEPGMGFKIAMQTLDM 246 Query: 276 GRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRN 335 GRI IAS +LG A AS+ + R FG PL Q +QF LADMA L +ARL+ Sbjct: 247 GRIGIASQALGIAQASLDCAVKYAENRHAFGAPLTKLQNIQFKLADMALALESARLLTWR 306 Query: 336 AAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQ 395 AA+ L++ +K +MAKL A++ AI +QA+Q+ GG GY+ + ++Y RD+R+ + Sbjct: 307 AAM-LKDNKKPFTKESAMAKLAASEAATAISHQAIQILGGMGYVTEMPAERYYRDARITE 365 Query: 396 ILEGSNEVMRILISRSLLQ 414 I EG++E+ R++I+ LL+ Sbjct: 366 IYEGTSEIQRLVIAGHLLR 384 >6FAH-C nrPDB Length = 379 Score = 259 bits (661), Expect = 2e-69, Method: Compositional matrix adjust. Identities = 148/381 (38%), Positives = 229/381 (60%), Gaps = 6/381 (1%) Query: 39 MGLNEEQKEFQKVAFDFAAREMAPN-MAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGG 97 M +E+ K +K+A DFA +E+ + E ++ FP +++ K A+ GF G+ I +GG Sbjct: 1 MYFSEQNKMIRKLARDFAEKELTTEILDEVEESGEFPQEILDKMAKFGFFGIKIPKSLGG 60 Query: 98 SGLSRLDTSVIFEALATGCTSTTAYISIHNMCAW--MIDSFGNEEQRHKFCPPLCTMEKF 155 SG + + E A + Y+S N A ++ S G EEQ K+ P+ T +K Sbjct: 61 SGGDHMSYVICMEEFARVSGVASVYLSSPNSLAGGPLLLS-GTEEQIEKYLKPIITGKKK 119 Query: 156 ASYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTG-GPGPKG 214 ++ LTEPG+GSDA + T+A GD+Y+LNG K FI+ A D V+ +T G +G Sbjct: 120 LAFALTEPGAGSDAGGMSTTAVDMGDYYLLNGRKTFITMAPLCDDAVIYAKTDMSKGTRG 179 Query: 215 ISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLN 274 IS +V+ + G+S GK E K+G T +I ED VP NR+G +GF A++ L+ Sbjct: 180 ISAFIVDLKSEGVSMGKNEHKMGLIGCATSDIIMEDVKVPKENRLGEVNKGFSNAMKTLD 239 Query: 275 GGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVR 334 GR+ +AS S+G A ++ + RKQFG+ +A Q + F +ADMAT+L AA+L+V Sbjct: 240 VGRLGVASQSIGVAQGALDEAIKYAKERKQFGKRIADFQAIAFMIADMATKLEAAKLLVY 299 Query: 335 NAAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVH 394 NAA +L + +K+A SMAK +A++ C IC +A+Q+HGGYGY+K+Y V++ RD RV Sbjct: 300 NAA-SLMDNKKNATKEASMAKFYASEICNEICAKAVQIHGGYGYIKEYKVERMYRDCRVF 358 Query: 395 QILEGSNEVMRILISRSLLQE 415 I EG+++V +++IS LL++ Sbjct: 359 TIYEGTSQVQQMVISGMLLKK 379 >2VIG-A nrPDB Length = 391 Score = 254 bits (648), Expect = 6e-68, Method: Compositional matrix adjust. Identities = 141/379 (37%), Positives = 227/379 (59%), Gaps = 3/379 (0%) Query: 38 SMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGG 97 S+ L E + + DFA +E+ P A+ D++ LFP ++K LG + + ++GG Sbjct: 3 SVELPETHQMLLQTCRDFAEKELFPIAAQVDKEHLFPAAQVKKMGGLGLLAMDVPEELGG 62 Query: 98 SGLSRLDTSVIFEALATGCTSTTAYISIHN-MCAWMIDSFGNEEQRHKFCPPLCTMEKFA 156 +GL L ++ E ++ GC ST +S++N + I FG++EQ+ + P + +K Sbjct: 63 AGLDYLAYAIAMEEISRGCASTGVIMSVNNSLYLGPILKFGSKEQKQAWVTPFTSGDKIG 122 Query: 157 SYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTG-GPGPKGI 215 + L+EPG+GSDA + T+A+ +GD ++LNG+KA+I+ A E+ VV T K I Sbjct: 123 CFALSEPGNGSDAGAASTTARAEGDSWVLNGTKAWITNAWEASAAVVFASTDRALQNKSI 182 Query: 216 SCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNG 275 S +V TPGL+ GKKE K+G T +IFEDC +P + +G G GF IA++ L+ Sbjct: 183 SAFLVPMPTPGLTLGKKEDKLGIRGSSTANLIFEDCRIPKDSILGEPGMGFKIAMQTLDM 242 Query: 276 GRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRN 335 GRI IAS +LG A ++ ++ R FG PL Q +QF LADMA L +ARL+ Sbjct: 243 GRIGIASQALGIAQTALDCAVNYAENRMAFGAPLTKLQVIQFKLADMALALESARLLTWR 302 Query: 336 AAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQ 395 AA+ L++ +K + +MAKL A++ AI +QA+Q+ GG GY+ + +++ RD+R+ + Sbjct: 303 AAM-LKDNKKPFIKEAAMAKLAASEAATAISHQAIQILGGMGYVTEMPAERHYRDARITE 361 Query: 396 ILEGSNEVMRILISRSLLQ 414 I EG++E+ R++I+ LL+ Sbjct: 362 IYEGTSEIQRLVIAGHLLR 380 >4N5F-A nrPDB Length = 385 Score = 251 bits (642), Expect = 3e-67, Method: Compositional matrix adjust. Identities = 137/374 (36%), Positives = 220/374 (58%), Gaps = 5/374 (1%) Query: 42 NEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGLS 101 E+Q+ + A FA +APN A+WD P ++ + +LG G+ + ++GGS Sbjct: 14 TEDQRMIRDAARAFATEMLAPNAAQWDHDAHLPDAIVAQLGELGLLGMIVPQELGGSYTD 73 Query: 102 RLDTSVIFEALATGCTSTTAYISIHNM--CAWMIDSFGNEEQRHKFCPPLCTMEKFASYC 159 + ++ E +A G + +S+HN C ++ FG Q+ ++ + ++C Sbjct: 74 YVAYALAMEEVAAGDAACATMMSVHNSVGCGPIL-GFGTPAQKDRWLADMAAGRVIGAFC 132 Query: 160 LTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGG-PGPKGISCI 218 LTEP +GS+A +L T A+ + ++LNG+K F++ + + +V T G +GIS Sbjct: 133 LTEPHAGSEANNLRTRAELRDGQWVLNGAKQFVTNGQRAGVAIVFAMTDPEAGKRGISAF 192 Query: 219 VVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGGRI 278 +V TPG GK EKK+G + T + FE+CA+P N +G+ G+G IA+ L GGRI Sbjct: 193 LVPTDTPGFIVGKPEKKMGIRASDTCPITFENCAIPEDNLLGNRGEGLKIALSNLEGGRI 252 Query: 279 NIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNAAV 338 IA+ +LG A A+ R + R QFG+P+A +Q +Q LADMA ++ AARL+V +AA Sbjct: 253 GIAAQALGIARAAFDKARRYAGERVQFGKPIAEHQAIQQKLADMAVQINAARLLVHHAA- 311 Query: 339 ALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQILE 398 L+ ++ S AKLFA++ +C+ A+Q+HGGYGYL DY V+++ RD+R+ QI E Sbjct: 312 KLRTAGLPCLSEASQAKLFASEMAERVCSDAIQIHGGYGYLVDYEVERHYRDARITQIYE 371 Query: 399 GSNEVMRILISRSL 412 G++EV R++I+R L Sbjct: 372 GTSEVQRMVIARQL 385 >4M9A-A nrPDB Length = 385 Score = 250 bits (638), Expect = 9e-67, Method: Compositional matrix adjust. Identities = 140/374 (37%), Positives = 223/374 (59%), Gaps = 5/374 (1%) Query: 42 NEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGLS 101 E+Q+ A F A +APN A+WD++ P +V+ + +LGF G+ + D GGS Sbjct: 14 TEDQRMILDAARAFCAEVLAPNAAQWDRESHLPDEVVAQMGELGFLGMIVPADWGGSYTD 73 Query: 102 RLDTSVIFEALATGCTSTTAYISIHNM--CAWMIDSFGNEEQRHKFCPPLCTMEKFASYC 159 + ++ E +A GC S +S+HN C +++ +G EQ+ ++ L + + ++ Sbjct: 74 YVAYALALEEIAAGCASCATLVSVHNSVGCGPVLN-YGTTEQKERWLRDLASGKTVGAFS 132 Query: 160 LTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTG-GPGPKGISCI 218 LTEP +GS+A +L T A+ + +ILNGSK F++ + + +V T G +G+S Sbjct: 133 LTEPHAGSEAHNLRTRAELRDGKWILNGSKQFVTNGARAGLAIVFAMTDPDEGKRGLSAF 192 Query: 219 VVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGGRI 278 VV TPG GK EKK+G + T + E+CA+P N +G G+G IA+ L GGRI Sbjct: 193 VVPTDTPGFIVGKPEKKMGIRASDTCPITLENCAIPQENLLGKRGEGLKIALSNLEGGRI 252 Query: 279 NIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNAAV 338 IA+ + G A A+ R + R QFG+P+A +Q + LA+MAT++ AARL+ +AA Sbjct: 253 GIAAQATGIARAAFDRARRYARERVQFGKPIAEHQAIAEKLANMATQINAARLLTHHAA- 311 Query: 339 ALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQILE 398 L+ ++ S AKLFA++ A+C+ A+Q+HGGYG+L DY V+++ RD+R+ QI E Sbjct: 312 RLRTAGLPCLSEASQAKLFASEMAEAVCSDAIQIHGGYGFLVDYEVERHYRDARITQIYE 371 Query: 399 GSNEVMRILISRSL 412 G++EV R++I+R L Sbjct: 372 GTSEVQRMVIARQL 385 >1BUC-A nrPDB Length = 383 Score = 244 bits (623), Expect = 5e-65, Method: Compositional matrix adjust. Identities = 144/380 (37%), Positives = 220/380 (57%), Gaps = 7/380 (1%) Query: 41 LNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGL 100 L + Q++F K+A DF +++AP + E D K ++ +++ + LG G Y + GGSG Sbjct: 5 LTDIQQDFLKLAHDFGEKKLAPTVTERDHKGIYDKELIDELLSLGITGAYFEEKYGGSGD 64 Query: 101 SR---LDTSVIFEALATGCTSTTAYISIH-NMCAWMIDSFGNEEQRHKFCPPLCTMEKFA 156 L + E LA +S ++CA I FG E Q+ KF PL K Sbjct: 65 DGGDVLSYILAVEELAKYDAGVAITLSATVSLCANPIWQFGTEAQKEKFLVPLVEGTKLG 124 Query: 157 SYCLTEPGSGSDAASLLTSAKKQGD-HYILNGSKAFISGAGESDIYVVMCRTG-GPGPKG 214 ++ LTEP +G+DA+ T A K D Y LNGSK FI+ G +DIY+V T G G Sbjct: 125 AFGLTEPNAGTDASGQQTIATKNDDGTYTLNGSKIFITNGGAADIYIVFAMTDKSKGNHG 184 Query: 215 ISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLN 274 I+ ++E GTPG ++GKKE K+G ++ T ++F+D VP N +G EG+GF IA+ L+ Sbjct: 185 ITAFILEDGTPGFTYGKKEDKMGIHTSQTMELVFQDVKVPAENMLGEEGKGFKIAMMTLD 244 Query: 275 GGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVR 334 GGRI +A+ +LG A A++ ++ R QFG+PL Q + F LADM ++ AAR +V Sbjct: 245 GGRIGVAAQALGIAEAALADAVEYSKQRVQFGKPLCKFQSISFKLADMKMQIEAARNLVY 304 Query: 335 NAAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVH 394 AA QE + V ++AK A+D + +A+Q+ GGYGY ++Y V +++RD+++ Sbjct: 305 KAACKKQEGKPFTVD-AAIAKRVASDVAMRVTTEAVQIFGGYGYSEEYPVARHMRDAKIT 363 Query: 395 QILEGSNEVMRILISRSLLQ 414 QI EG+NEV ++ +LL+ Sbjct: 364 QIYEGTNEVQLMVTGGALLR 383 >3MDE-A nrPDB Length = 385 Score = 244 bits (622), Expect = 7e-65, Method: Compositional matrix adjust. Identities = 133/378 (35%), Positives = 214/378 (56%), Gaps = 5/378 (1%) Query: 38 SMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGG 97 S L E+QKEFQ A FA E+ P AE+D+ +PV ++++A +LG +I GG Sbjct: 3 SFELTEQQKEFQATARKFAREEIIPVAAEYDRTGEYPVPLLKRAWELGLMNTHIPESFGG 62 Query: 98 SGLSRLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSFGNEEQRHKFCPPLCTMEKFAS 157 GL +D+ +I E LA GCT I + + + GN +Q+ K+ + + Sbjct: 63 LGLGIIDSCLITEELAYGCTGVQTAIEANTLGQVPLIIGGNYQQQKKYLGRMTEEPLMCA 122 Query: 158 YCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTG----GPGPK 213 YC+TEPG+GSD A + T A+K+GD YI+NG K +I+ G+++ Y ++ R+ P K Sbjct: 123 YCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPASK 182 Query: 214 GISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGL 273 + +VE TPG+ G+KE +G TR ++FED VP N + EG GF IA+ Sbjct: 183 AFTGFIVEADTPGVQIGRKEINMGQRCSDTRGIVFEDVRVPKENVLTGEGAGFKIAMGTF 242 Query: 274 NGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMV 333 + R +A+ ++G A ++ + RK FG+ LA +Q + F LADMA ++ ARL Sbjct: 243 DKTRPPVAAGAVGLAQRALDEATKYALERKTFGKLLAEHQGISFLLADMAMKVELARLSY 302 Query: 334 RNAAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRV 393 + AA + R++ S+AK +A D + A+Q+ GG G+ +Y V++ +RD+++ Sbjct: 303 QRAAWEIDSGRRNTY-YASIAKAYAADIANQLATDAVQVFGGNGFNTEYPVEKLMRDAKI 361 Query: 394 HQILEGSNEVMRILISRS 411 +QI EG+ ++ RI+I+R Sbjct: 362 YQIYEGTAQIQRIIIARE 379 >3PFD-A nrPDB Length = 393 Score = 243 bits (619), Expect = 2e-64, Method: Compositional matrix adjust. Identities = 133/375 (35%), Positives = 211/375 (56%), Gaps = 1/375 (0%) Query: 41 LNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGL 100 L EE ++ A +E+AP AE D+K FP + + GF +++ + GG G Sbjct: 19 LPEEHIALREAIRALAEKEIAPYAAEVDEKARFPEEALAALNSSGFSAIHVPEEYGGQGA 78 Query: 101 SRLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSFGNEEQRHKFCPPLCTMEKFASYCL 160 + T ++ E +A S + +++ + + G+EE + + P + + E ASY L Sbjct: 79 DSVATCIVIEEVARVDCSASLIPAVNKLGTMGLILRGSEELKKQVLPAVASGEAMASYAL 138 Query: 161 TEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTG-GPGPKGISCIV 219 +E +GSDAAS+ T A GD +ILNGSK +I+ G+S Y VM T G GIS + Sbjct: 139 SEREAGSDAASMRTRAVADGDDWILNGSKCWITNGGKSTWYTVMAVTDPDKGANGISAFM 198 Query: 220 VEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGGRIN 279 V K G + G KE+K+G PT + FE+C +P IG G GF A+ L+ R Sbjct: 199 VHKDDEGFTVGPKERKLGIKGSPTTELYFENCRIPGDRIIGEPGTGFKTALATLDHTRPT 258 Query: 280 IASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNAAVA 339 I + ++G A ++ + RKQFG P++ NQ +QF LADMA ++ AARLMV +AA Sbjct: 259 IGAQAVGIAQGALDAAIAYTKERKQFGRPVSDNQGVQFMLADMAMKIEAARLMVYSAAAR 318 Query: 340 LQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQILEG 399 + D + + +K FA+D + A+Q+ GGYGY +D+ V++ +RD+++ QI EG Sbjct: 319 AERGEGDLGFISAASKCFASDVAMEVTTDAVQLFGGYGYTQDFPVERMMRDAKITQIYEG 378 Query: 400 SNEVMRILISRSLLQ 414 +N++ R+++SR+LL+ Sbjct: 379 TNQIQRVVMSRALLR 393 >2A1T-A nrPDB Length = 421 Score = 240 bits (612), Expect = 9e-64, Method: Compositional matrix adjust. Identities = 131/403 (32%), Positives = 224/403 (55%), Gaps = 9/403 (2%) Query: 21 RVLVQTGHRSLTSCIDPSMGLN----EEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVD 76 R ++ H +P +G + E+QKEFQ A FA E+ P AE+D+ +PV Sbjct: 17 RFHWRSQHTKANRQREPGLGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVP 76 Query: 77 VMRKAAQLGFGGVYIQTDVGGSGLSRLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSF 136 ++R+A +LG +I + GG GL D +I E LA GCT I +++ I Sbjct: 77 LIRRAWELGLMNTHIPENCGGLGLGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIIIA 136 Query: 137 GNEEQRHKFCPPLCTMEKFASYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAG 196 GN++Q+ K+ + +YC+TEPG+GSD A + T A+K+GD YI+NG K +I+ G Sbjct: 137 GNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGG 196 Query: 197 ESDIYVVMCRTG----GPGPKGISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCA 252 +++ Y ++ R+ P K + +VE TPG+ G+KE +G TR ++FED Sbjct: 197 KANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVK 256 Query: 253 VPVANRIGSEGQGFLIAVRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASN 312 VP N + +G GF +A+ + R +A+ ++G A ++ + RK FG+ L + Sbjct: 257 VPKENVLIGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEH 316 Query: 313 QYLQFTLADMATRLVAARLMVRNAAVALQEERKDAVALCSMAKLFATDECFAICNQALQM 372 Q + F LA+MA ++ AR+ + AA + R++ S+AK FA D + A+Q+ Sbjct: 317 QAISFMLAEMAMKVELARMSYQRAAWEVDSGRRNTY-YASIAKAFAGDIANQLATDAVQI 375 Query: 373 HGGYGYLKDYAVQQYVRDSRVHQILEGSNEVMRILISRSLLQE 415 GG G+ +Y V++ +RD++++QI EG++++ R++++R + + Sbjct: 376 LGGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAREHIDK 418 >2DVL-A nrPDB Length = 372 Score = 232 bits (592), Expect = 2e-61, Method: Compositional matrix adjust. Identities = 138/378 (36%), Positives = 224/378 (59%), Gaps = 8/378 (2%) Query: 39 MGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGS 98 M L +EQ+ A + P E+D+K +P ++ A+LG G+ + GG Sbjct: 1 MTLTQEQRLVLDAVRRVAREVLYPLAPEYDRKAEYPWPQLKALAELGLLGMTTPEEWGGV 60 Query: 99 GLSRLDTSVIFEALATGCTSTTAYISIHN-MCAWMIDSFGNEEQRHKFCPPLCTMEKFAS 157 GL + ++ E LA S +S+ + + +M+ FG+E Q+ ++ PL E + Sbjct: 61 GLDSVTWALALEELAAADPSVAVIVSVTSGLPQYMLLRFGSEAQKRRYLVPLARGEWIGA 120 Query: 158 YCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGGPGPKGISC 217 +CLTEP +GSDA SL A++ ++LNG K++I+ AG + +YVVM RT KGIS Sbjct: 121 FCLTEPQAGSDAKSLRAEARRVKGGFVLNGVKSWITSAGHAHLYVVMART----EKGISA 176 Query: 218 IVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGGR 277 +VEKGTPGLSFG+ E+K+G ++ T V E+ VP N +G EG+G A+ GL+ GR Sbjct: 177 FLVEKGTPGLSFGRPEEKMGLHAAHTAEVRLEEVFVPEENLLGEEGRGLAYALAGLDSGR 236 Query: 278 INIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNAA 337 + +A+ ++G A + + + + R+QFG+ L +Q + F +ADM ++ AAR +V A Sbjct: 237 VGVAAQAVGIARGAFEIAKAYAEEREQFGKKLKEHQAIAFKIADMHVKIAAARALVLEA- 295 Query: 338 VALQEERKDAVAL-CSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQI 396 A +++R + L S AKLFA+ + +A+Q+ GGYGY +DY V++Y RD++V +I Sbjct: 296 -ARKKDRGERFTLEASAAKLFASAAAVEVTREAVQVLGGYGYHRDYRVERYYRDAKVTEI 354 Query: 397 LEGSNEVMRILISRSLLQ 414 EG++E+ R++I+R L + Sbjct: 355 YEGTSEIQRLVIARELYR 372 >2Z1Q-A nrPDB Length = 577 Score = 231 bits (590), Expect = 3e-61, Method: Compositional matrix adjust. Identities = 133/390 (34%), Positives = 214/390 (54%), Gaps = 19/390 (4%) Query: 41 LNEEQKEFQKVAFDFAAREMAPNMAEWDQKEL-FPVDVMRKAAQLGFGGVYIQTDVGGSG 99 +E KE + F RE+ P + + EL V +MRKA +LG + + + GG Sbjct: 28 FDESVKEIARTTRTFVEREVLPLLERMEHGELELNVPLMRKAGELGLLAIDVPEEYGGLD 87 Query: 100 LSRLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSFGNEEQRHKFCPPLCTMEKFASYC 159 L ++ ++V+ E L+ + Y + ++ + FG EEQ+ K+ P L + E A+YC Sbjct: 88 LPKVISTVVAEELSGSGGFSVTYGAHTSIGTLPLVYFGTEEQKRKYLPKLASGEWIAAYC 147 Query: 160 LTEPGSGSDAASLLTSA--KKQGDHYILNGSKAFISGAGESDIYVVMCRTGGPGPKGISC 217 LTEPGSGSDA + T A + G HYILNG K +IS AG + ++ V + G + + Sbjct: 148 LTEPGSGSDALAAKTRATLSEDGKHYILNGVKQWISNAGFAHLFTVFAKVDG---EHFTA 204 Query: 218 IVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGGR 277 +VE+ TPGLSFG +EKK+G + TR VI ED VPV N +G G+G IA LN GR Sbjct: 205 FLVERDTPGLSFGPEEKKMGIKASSTRQVILEDVKVPVENVLGEIGKGHKIAFNVLNVGR 264 Query: 278 INIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAAR------- 330 + + ++G A ++ L+ + R QFG P+ +Q L +MA+R+ AA Sbjct: 265 YKLGAGAVGGAKRALELSAQYATQRVQFGRPIGRFGLIQQKLGEMASRIYAAESAVYRTV 324 Query: 331 ------LMVRNAAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAV 384 L+ + A+ ++ S+ K+ ++ + ++ +Q+HGGYGY ++Y + Sbjct: 325 GLIDEALLGKKGPEAVMAGIEEYAVEASIIKVLGSEVLDYVVDEGVQIHGGYGYSQEYPI 384 Query: 385 QQYVRDSRVHQILEGSNEVMRILISRSLLQ 414 ++ RD+R+++I EG+NE+ R+LI LL+ Sbjct: 385 ERAYRDARINRIFEGTNEINRLLIPGMLLR 414 >2PG0-A nrPDB Length = 385 Score = 230 bits (586), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 131/376 (34%), Positives = 204/376 (54%), Gaps = 6/376 (1%) Query: 41 LNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGL 100 L EE F+ F +E P+ +W+++ + P K + GF ++ GG Sbjct: 10 LREEHHMFRAAFRKFLEKEAYPHYNDWEKRGIIPRSFWAKMGENGFLCPWVDEKYGGLNA 69 Query: 101 SRLDTSVIFEALATGCTSTTAYISIHN-MCAWMIDSFGNEEQRHKFCPPLCTMEKFASYC 159 + VI E L +S I +HN + I S+G EEQ+ K+ P T E + Sbjct: 70 DFAYSVVINEELEKVGSSLVG-IGLHNDIVTPYIASYGTEEQKQKWLPKCVTGELITAIA 128 Query: 160 LTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRT---GGPGPKGIS 216 +TEPG+GSD A++ T+A K GD+YI+NG K FI+ +D+ VV C+T P +GIS Sbjct: 129 MTEPGAGSDLANISTTAVKDGDYYIVNGQKTFITNGIHADLIVVACKTDPQAKPPHRGIS 188 Query: 217 CIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGG 276 +VVE+ TPG + G+K +KVG ++Q T + F+D VP N +G EG+GF + L Sbjct: 189 LLVVERDTPGFTRGRKLEKVGLHAQDTAELFFQDAKVPAYNLLGEEGKGFYYLMEKLQQE 248 Query: 277 RINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNA 336 R+ +A + AA LT+ ++ R FG+ ++ Q +QF LA+MAT + R V + Sbjct: 249 RLVVAIAAQTAAEVMFSLTKQYVKQRTAFGKRVSEFQTVQFRLAEMATEIALGRTFV-DR 307 Query: 337 AVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQI 396 + K V SMAK + T+ + +A+Q+HGGYGY+++Y + + RD V I Sbjct: 308 VIEEHMAGKQIVTEVSMAKWWITEMAKRVAAEAMQLHGGYGYMEEYEIARRYRDIPVSAI 367 Query: 397 LEGSNEVMRILISRSL 412 G+NE+M+ +I+R L Sbjct: 368 YAGTNEMMKTIIARQL 383 >2JIF-A nrPDB Length = 404 Score = 226 bits (575), Expect = 2e-59, Method: Compositional matrix adjust. Identities = 136/378 (35%), Positives = 208/378 (55%), Gaps = 4/378 (1%) Query: 37 PSMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVG 96 P +E+ + FA ++AP ++ D+ V++ Q G G+ + + G Sbjct: 25 PLQTFTDEEMMIKSSVKKFAQEQIAPLVSTMDENSKMEKSVIQGLFQQGLMGIEVDPEYG 84 Query: 97 GSGLSRLDTSVIFEALATGCTSTTAYISIHN-MCAWMIDSFGNEEQRHKFCPPLCTMEKF 155 G+G S L T ++ E LA S + I N + +I G EEQ+ + P L T EK Sbjct: 85 GTGASFLSTVLVIEELAKVDASVAVFCEIQNTLINTLIRKHGTEEQKATYLPQLTT-EKV 143 Query: 156 ASYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGGP-GPKG 214 S+CL+E G+GSD+ +L T A K+GD+Y+LNGSK +IS A + +++VM G KG Sbjct: 144 GSFCLSEAGAGSDSFALKTRADKEGDYYVLNGSKMWISSAEHAGLFLVMANVDPTIGYKG 203 Query: 215 ISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLN 274 I+ +V++ TPGL GK E K+G + T + FE+ VP AN +G G G+ A+ LN Sbjct: 204 ITSFLVDRDTPGLHIGKPENKLGLRASSTCPLTFENVKVPEANILGQIGHGYKYAIGSLN 263 Query: 275 GGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVR 334 GRI IA+ LG A T ++ R QFG+ L Q LQ +A +AT+L AARL+ Sbjct: 264 EGRIGIAAQMLGLAQGCFDYTIPYIKERIQFGKRLFDFQGLQHQVAHVATQLEAARLLTY 323 Query: 335 NAAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVH 394 NAA L E K + SMAK +A++ ++ ++ GG GY KDY V++Y RD+++ Sbjct: 324 NAA-RLLEAGKPFIKEASMAKYYASEIAGQTTSKCIEWMGGVGYTKDYPVEKYFRDAKIG 382 Query: 395 QILEGSNEVMRILISRSL 412 I EG++ + I++ + Sbjct: 383 TIYEGASNIQLNTIAKHI 400 >3OWA-A nrPDB Length = 597 Score = 224 bits (572), Expect = 4e-59, Method: Compositional matrix adjust. Identities = 130/396 (32%), Positives = 218/396 (55%), Gaps = 30/396 (7%) Query: 44 EQKEFQKVAFDFAAREMAPNMAEWDQKEL-FPVDVMRKAAQLGFGGVYIQTDVGGSGLSR 102 E K K DF E+ P + +Q E V ++++A +LG G + + GG GL + Sbjct: 36 EHKMIAKTTEDFIVNEVLPELEYLEQHEFDRSVRLLKEAGELGLLGADVPEEYGGIGLDK 95 Query: 103 LDTSVIFEALATG---CTSTTAYISIHNMCAWMIDSFGNEEQRHKFCPPLCTMEKFASYC 159 + +++I E + + A++ I ++ + FGNEEQ+ K+ P L T EK A+Y Sbjct: 96 VSSALIAEKFSRAGGFAITHGAHVGIGSLPIVL---FGNEEQKKKYLPLLATGEKLAAYA 152 Query: 160 LTEPGSGSDAASLLTSAK--KQGDHYILNGSKAFISGAGESDIYVVMCRTGGPGPKGISC 217 LTEPGSGSDA T+A+ +G HY+LNG K +I+ + +D+++V + G + S Sbjct: 153 LTEPGSGSDALGAKTTARLNAEGTHYVLNGEKQWITNSAFADVFIVYAKIDG---EHFSA 209 Query: 218 IVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGGR 277 +VEK G+S +EKK+G TR +I ED VP N +G G+G +IA LN GR Sbjct: 210 FIVEKDYAGVSTSPEEKKMGIKCSSTRTLILEDALVPKENLLGEIGKGHIIAFNILNIGR 269 Query: 278 INIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAAR------- 330 + ++G+A +V ++ + N R+QF +P+A +Q LA+MA + AA Sbjct: 270 YKLGVGTVGSAKRAVEISAQYANQRQQFKQPIARFPLIQEKLANMAAKTYAAESSVYRTV 329 Query: 331 -LMVRNAAVALQEERKDAVAL----------CSMAKLFATDECFAICNQALQMHGGYGYL 379 L + +EE KD A+ CS+ K+F ++ ++ +Q+HGGYG++ Sbjct: 330 GLFESRMSTLSEEEVKDGKAVAASIAEYAIECSLNKVFGSEVLDYTVDEGVQIHGGYGFM 389 Query: 380 KDYAVQQYVRDSRVHQILEGSNEVMRILISRSLLQE 415 +Y +++ RDSR+++I EG+NE+ R+++ + L++ Sbjct: 390 AEYEIERMYRDSRINRIFEGTNEINRLIVPGTFLRK 425 >4O5M-A nrPDB Length = 390 Score = 224 bits (572), Expect = 4e-59, Method: Compositional matrix adjust. Identities = 131/383 (34%), Positives = 208/383 (54%), Gaps = 9/383 (2%) Query: 38 SMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGG 97 + GL EE + + FA +AP AE D+ FP+ + R+ +LG G+ D GG Sbjct: 10 NFGLGEEIEALRDTVRRFAESRIAPLAAETDRNNQFPMHLWREFGELGVLGITAPEDYGG 69 Query: 98 SGLSRLDTSVIFEALATGCTSTTAYISIH-NMCAWMIDSFGNEEQRHKFCPPLCTMEKFA 156 +G+ L + E ++ S H N+C I G+ EQR K+ P L + E Sbjct: 70 AGMGYLAHCIAMEEISRASASIGLSYGAHSNLCVNQITRNGSPEQRAKYLPKLISGEHVG 129 Query: 157 SYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTG-GPGPKGI 215 + ++EPG+GSD S+ +A+K+GD Y+LNG+K +I+ ++D+ VV +T GP+GI Sbjct: 130 ALAMSEPGAGSDVVSMKLAAEKRGDRYVLNGNKMWITNGPDADVLVVYAKTDLSAGPRGI 189 Query: 216 SCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNG 275 S ++EKG G S +K K+G T ++FEDC VP N +G+EG+G + + GL+ Sbjct: 190 SAFIIEKGFKGFSTAQKLDKLGMRGSNTCELVFEDCEVPAENLLGTEGKGVNVLMSGLDY 249 Query: 276 GRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRN 335 R+ +A LG A + + +++ RKQF +P+ Q +Q LADM A+R V Sbjct: 250 ERVVLAGGPLGIMAACLDVVVPYVHERKQFDQPIGEFQLMQCKLADMYVTFNASRAYVYA 309 Query: 336 AAVAL---QEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSR 392 A A + RKDA L++ + + QA+Q GG GY+ DY + +RD++ Sbjct: 310 VAAACDRGETTRKDAAGCI----LYSAENATQMALQAIQSLGGNGYINDYPTGRLLRDAK 365 Query: 393 VHQILEGSNEVMRILISRSLLQE 415 +++I G++E+ R+LI R L QE Sbjct: 366 LYEIGAGTSEIRRMLIGRELFQE 388 >4IV6-A nrPDB Length = 388 Score = 223 bits (568), Expect = 1e-58, Method: Compositional matrix adjust. Identities = 131/384 (34%), Positives = 213/384 (55%), Gaps = 14/384 (3%) Query: 38 SMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGG 97 SM L E++ K DF +++ P + E + +P +++ ++G G+ I G Sbjct: 4 SMALTAEEETIVKTVHDFVEKQVKPVVRELEHANTYPEELIETMKEIGIFGLAIPEPYGF 63 Query: 98 SGLSRLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSFGNEEQRHKFCPPLCTMEKFAS 157 +S + E LA G S + H + + ++ FG EEQ+ K+ P + T E A+ Sbjct: 64 GAVSMPCYVQVAEELARGWMSLAGAMGGHTVVSKLLLLFGTEEQKQKYLPRMATGELRAT 123 Query: 158 YCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRT---GGPGPKG 214 LTEPG GSD ++ T A++ GD Y++NGSK +IS A SD+ +MC+T P KG Sbjct: 124 MALTEPGGGSDLQAMRTVARRDGDDYVINGSKTWISNARRSDLVALMCKTDPDAQPAHKG 183 Query: 215 ISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIG-SEGQGFLIAVRGL 273 +S ++VEK PG + K+G+ + + F D VPV++ +G EG+GF ++GL Sbjct: 184 VSILLVEK-VPGFDVSRDLPKLGYKGVESCELNFTDARVPVSSLLGDDEGRGFAQMMKGL 242 Query: 274 NGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMV 333 GR+ +A+ + G A A+ + R+ FG+P+ +Q + LADM T+L AAR ++ Sbjct: 243 EVGRLQVAARATGVARAAFEDALRYSQERESFGKPIWQHQSVGNMLADMGTKLYAARSLL 302 Query: 334 RNAAVALQEERKDAVALCS----MAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVR 389 +AA E+ DA C MAKLFA++ I A+++HGGYGY +Y V++Y R Sbjct: 303 LSAA-----EKFDAGQRCDMEAGMAKLFASETAMQIALDAVRVHGGYGYSTEYDVERYFR 357 Query: 390 DSRVHQILEGSNEVMRILISRSLL 413 D+ + + EG+NE+ R +I++ L+ Sbjct: 358 DAPLMIVGEGTNEIQRNVIAKQLV 381 >2CX9-A nrPDB Length = 387 Score = 222 bits (565), Expect = 3e-58, Method: Compositional matrix adjust. Identities = 138/367 (37%), Positives = 213/367 (58%), Gaps = 7/367 (1%) Query: 54 DFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGLSRLDTSVIFEALA 113 +F E+AP AE D+ FP D++RK A+ G G + GG+GLS + + EA+A Sbjct: 20 EFLKAEVAPGAAERDRTGAFPWDLVRKLAEFGVFGALVPEAYGGAGLSTRLFARMVEAIA 79 Query: 114 TGCTSTTAYISIHN-MCAWMIDSFGNEEQRHKFCPPLCTMEKFASYCLTEPGSGSDAASL 172 + ++ HN + I G+E Q+ F P L + E ++ LTEPGSGSDAA+L Sbjct: 80 YYDGALALTVASHNSLATGHILLAGSEAQKEAFLPKLASGEALGAWGLTEPGSGSDAAAL 139 Query: 173 LTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGGPGP-----KGISCIVVEKGTPGL 227 T A+K + LNG+K FI+ + +YVVM RT P +GIS + GL Sbjct: 140 KTKAEKVEGGWRLNGTKQFITQGSVAGVYVVMARTDPPPSPERKHQGISAFAFFRPERGL 199 Query: 228 SFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGGRINIASCSLGA 287 G+KE+K+G + T +I ED VP +G G+GF +R L+GGRI IA+ ++G Sbjct: 200 KVGRKEEKLGLTASDTAQLILEDLFVPEEALLGERGKGFYDVLRVLDGGRIGIAAMAVGL 259 Query: 288 AHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNAAVALQEERKDA 347 A++ + R+ FG P+A + + F LA+ AT L AARL+ AA L++ + Sbjct: 260 GQAALDYALAYAKGREAFGRPIAEFEGVSFKLAEAATELEAARLLYLKAA-ELKDAGRPF 318 Query: 348 VALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQILEGSNEVMRIL 407 + AKLFA++ C++A+Q+ GGYGY+KDY V++Y RD+R+ +I EG++E+++++ Sbjct: 319 TLEAAQAKLFASEAAVKACDEAIQILGGYGYVKDYPVERYWRDARLTRIGEGTSEILKLV 378 Query: 408 ISRSLLQ 414 I+R LL+ Sbjct: 379 IARRLLE 385 >3R7K-A nrPDB Length = 403 Score = 221 bits (563), Expect = 5e-58, Method: Compositional matrix adjust. Identities = 123/381 (32%), Positives = 205/381 (53%), Gaps = 3/381 (0%) Query: 34 CIDPSMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQT 93 + P E++ ++A F RE+AP +AEW+ P D+ AA++G G+ Sbjct: 22 VVAPEAWTTPERRALSQMARSFVEREIAPKLAEWEHVGEIPRDLHLNAAEVGLLGIGFPE 81 Query: 94 DVGGSGLSRLDTSVIFEAL--ATGCTSTTAYISIHNMCAWMIDSFGNEEQRHKFCPPLCT 151 +VGGSG + +D++++ EA+ A G T A + H + I + G++ ++ P Sbjct: 82 EVGGSGGNAIDSALVTEAILAAGGSTGVCAALFTHGIALPHIAANGSDALIERYVRPTLA 141 Query: 152 MEKFASYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGGPG 211 + S +TEPG+GSD A+L T A ++GD Y++NG+K FI+ +D RTGGPG Sbjct: 142 GKMIGSLGVTEPGAGSDVANLRTRAVREGDTYVVNGAKTFITSGVRADFVTTAVRTGGPG 201 Query: 212 PKGISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVR 271 G+S +V++K +PG ++ K+GW T + F D VP N +G+E GFL ++ Sbjct: 202 YGGVSLLVIDKNSPGFEVSRRLDKMGWRCSDTAELSFVDVRVPADNLVGAENSGFLQIMQ 261 Query: 272 GLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARL 331 R+ IA + A ++ L + R+ FG PL Q ++ LA+MA ++ A Sbjct: 262 QFQAERLGIAVQAYATAGRALDLAKSWARERETFGRPLTGRQIIRHKLAEMARQVDVACT 321 Query: 332 MVRNAAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDS 391 R A + +D VA SMAK A C + N+A+Q+ GG GY+++ ++++ RD Sbjct: 322 YTR-AVMQRWLAGEDVVAEVSMAKNTAVYACDYVVNEAVQIFGGMGYMRESEIERHYRDC 380 Query: 392 RVHQILEGSNEVMRILISRSL 412 R+ I G+NE+M +I++ + Sbjct: 381 RILGIGGGTNEIMNEVIAKRI 401 >1IVH-A nrPDB Length = 394 Score = 220 bits (560), Expect = 1e-57, Method: Compositional matrix adjust. Identities = 127/390 (32%), Positives = 209/390 (53%), Gaps = 7/390 (1%) Query: 29 RSLTSCIDPSMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFP--VDVMRKAAQLGF 86 SL D GL+EEQ++ ++ F +AP E D+ F + ++ LG Sbjct: 1 HSLLPVDDAINGLSEEQRQLRQTMAKFLQEHLAPKAQEIDRSNEFKNLREFWKQLGNLGV 60 Query: 87 GGVYIQTDVGGSGLSRLDTSVIFEALATGCTSTTAYISIH-NMCAWMIDSFGNEEQRHKF 145 G+ GGSGL L+ ++ E ++ + H N+C + GNE Q+ K+ Sbjct: 61 LGITAPVQYGGSGLGYLEHVLVMEEISRASGAVGLSYGAHSNLCINQLVRNGNEAQKEKY 120 Query: 146 CPPLCTMEKFASYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMC 205 P L + E + ++EP +GSD S+ A+K+G+HYILNG+K +I+ ++D+ +V Sbjct: 121 LPKLISGEYIGALAMSEPNAGSDVVSMKLKAEKKGNHYILNGNKFWITNGPDADVLIVYA 180 Query: 206 RT---GGPGPKGISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSE 262 +T P +GI+ +VEKG PG S KK K+G T +IFEDC +P AN +G E Sbjct: 181 KTDLAAVPASRGITAFIVEKGMPGFSTSKKLDKLGMRGSNTCELIFEDCKIPAANILGHE 240 Query: 263 GQGFLIAVRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADM 322 +G + + GL+ R+ +A LG A + T +L+VR+ FG+ + Q +Q +ADM Sbjct: 241 NKGVYVLMSGLDLERLVLAGGPLGLMQAVLDHTIPYLHVREAFGQKIGHFQLMQGKMADM 300 Query: 323 ATRLVAARLMVRNAAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDY 382 TRL+A R V N A A E A C+ L++ + + +Q GG GY+ D+ Sbjct: 301 YTRLMACRQYVYNVAKACDEGHCTAKD-CAGVILYSAECATQVALDGIQCFGGNGYINDF 359 Query: 383 AVQQYVRDSRVHQILEGSNEVMRILISRSL 412 + +++RD+++++I G++EV R++I R+ Sbjct: 360 PMGRFLRDAKLYEIGAGTSEVRRLVIGRAF 389 >3NF4-A nrPDB Length = 387 Score = 215 bits (548), Expect = 2e-56, Method: Compositional matrix adjust. Identities = 124/371 (33%), Positives = 208/371 (56%), Gaps = 2/371 (0%) Query: 42 NEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGLS 101 ++E E ++ + A + + P + ++ E +P V + G + + GG G Sbjct: 17 SQEAAELIELTREIADKVLDPIVDRHEKDETYPEGVFEQLGAAGLLSLPQPEEWGGGGQP 76 Query: 102 RLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSFGNEEQRHKFCPPLCTMEKFASYCLT 161 + E +A S +S+H++ + + FG EEQ+ ++ P + + E+ +Y L+ Sbjct: 77 YEVYLQVLEEIAARWASVAVAVSVHSLSSHPLLVFGTEEQKKRWLPGMLSGEQIGAYSLS 136 Query: 162 EPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGGPGPKGISCIVVE 221 EP +GSDAA+L +A Y++NGSK++I+ G++D Y + RTG G +G+SC +V Sbjct: 137 EPQAGSDAAALRCAATPTDGGYVINGSKSWITHGGKADFYTLFARTG-EGSRGVSCFLVP 195 Query: 222 KGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGGRINIA 281 PGLSFGK E+K+G ++ PT + +++ + RIG EGQG IA L+ GR+ IA Sbjct: 196 ADQPGLSFGKPEEKMGLHAVPTTSAFYDNARIDADRRIGEEGQGLQIAFSALDSGRLGIA 255 Query: 282 SCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNAAVALQ 341 + + G A A++ + N R FG + +Q L F LADMA + AR +AA Sbjct: 256 AVATGLAQAALDEAVAYANERTAFGRKIIDHQGLGFLLADMAAAVATARATYLDAARRRD 315 Query: 342 EERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQILEGSN 401 + R + S+AKL ATD + A+Q+ GG GY +DY V++Y+R++++ QI EG+N Sbjct: 316 QGRPYS-QQASIAKLTATDAAMKVTTDAVQVFGGVGYTRDYRVERYMREAKIMQIFEGTN 374 Query: 402 EVMRILISRSL 412 ++ R++I+R L Sbjct: 375 QIQRLVIARGL 385 >4KTO-A nrPDB Length = 410 Score = 209 bits (533), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 129/380 (33%), Positives = 202/380 (53%), Gaps = 9/380 (2%) Query: 41 LNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGL 100 L EE + FA+ +AP + D+ FP+ + R+ +LG G+ GG+GL Sbjct: 33 LGEEIDALRASVRRFASERIAPLADDADRSNAFPMSLWREMGELGLLGITADEAHGGAGL 92 Query: 101 SRLDTSVIFEALATGCTSTTAYISIH-NMCAWMIDSFGNEEQRHKFCPPLCTMEKFASYC 159 L V E ++ S H N+C I+ G Q+ ++ P L + E + Sbjct: 93 GYLAHCVAMEEISRASASVGLSYGAHSNLCVNQINRNGKPAQKSRYLPKLISGEHVGALA 152 Query: 160 LTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTG-GPGPKGISCI 218 ++EPG+GSD S+ A K+GD Y+LNGSK +I+ ++D+ VV +T GP+GI+ Sbjct: 153 MSEPGAGSDVVSMKLKADKRGDRYVLNGSKMWITNGPDADVLVVYAKTDPAAGPRGITAF 212 Query: 219 VVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGGRI 278 +VEK PG S G+K K+G T +IF DC VP N +G G+G + + GL+ R+ Sbjct: 213 LVEKAFPGFSAGQKLDKLGMRGSNTSELIFTDCEVPEENVLGGVGEGVKVLMSGLDYERV 272 Query: 279 NIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNAAV 338 +++ LG A + + +L+ RKQFG+P+ Q +Q LADM + AAR V A Sbjct: 273 VLSAGPLGIMAACLDVVVPYLHERKQFGQPIGEFQLMQGKLADMYVTMNAARAYVYAVAA 332 Query: 339 AL---QEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQ 395 A + RKDA L+A ++ A+ +A+Q GG GY DY + +RD+++++ Sbjct: 333 ACDRGETARKDAAGCI----LYAAEKATAMALEAIQALGGNGYTNDYPAGRLLRDAKLYE 388 Query: 396 ILEGSNEVMRILISRSLLQE 415 I G++E+ R+LI R L E Sbjct: 389 IGAGTSEIRRMLIGRELFAE 408 >3P4T-A nrPDB Length = 403 Score = 204 bits (519), Expect = 5e-53, Method: Compositional matrix adjust. Identities = 132/378 (34%), Positives = 191/378 (50%), Gaps = 4/378 (1%) Query: 38 SMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGG 97 S+ E++ +K FA RE+ P+ EW++ P ++ RKAA+LG G D GG Sbjct: 23 SIWTTAEREALRKTVRAFAEREVLPHAHEWERAGEIPRELHRKAAELGLLGAGFPEDAGG 82 Query: 98 SGLSRLDTSVIFEALATGCTSTTAYISIHN---MCAWMIDSFGNEEQRHKFCPPLCTMEK 154 SG D VI E + + Y S+ MI S G++ + P EK Sbjct: 83 SGGDGADPVVICEEMHYAGSPGGVYASLFTCGIAVPHMIAS-GDQRLIDTYVRPTLRGEK 141 Query: 155 FASYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGGPGPKG 214 + +TEPG GSD L T A GDHY++NG+K +I+ +D V RTGGPG G Sbjct: 142 IGALAITEPGGGSDVGHLRTRADLDGDHYVINGAKTYITSGVRADYVVTAARTGGPGAGG 201 Query: 215 ISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLN 274 +S IVV+KGTPG +K K+GW S T + + D VPVAN +GSE GF Sbjct: 202 VSLIVVDKGTPGFEVTRKLDKMGWRSSDTAELSYTDVRVPVANLVGSENTGFAQIAAAFV 261 Query: 275 GGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVR 334 R+ +A+ + A + LT + R FG PL S Q +Q TLA MA R+ AR+ R Sbjct: 262 AERVGLATQAYAGAQRCLDLTVEWCRNRDTFGRPLISRQAVQNTLAGMARRIDVARVYTR 321 Query: 335 NAAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVH 394 + + +A AK A + + NQA+Q+ GG GY+ + V++ RD R+ Sbjct: 322 HVVERQLAGETNLIAEVCFAKNTAVEAGEWVANQAVQLFGGMGYMAESEVERQYRDMRIL 381 Query: 395 QILEGSNEVMRILISRSL 412 I G+ E++ L +++L Sbjct: 382 GIGGGTTEILTSLAAKTL 399 >4IRN-A nrPDB Length = 416 Score = 197 bits (502), Expect = 5e-51, Method: Compositional matrix adjust. Identities = 118/404 (29%), Positives = 207/404 (51%), Gaps = 7/404 (1%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELF 73 G +P G + TG + + + N +Q +F+K FA + + ++ + D++E+F Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSEFDFAWNSQQIQFRKKVIQFAQQSLISDLIKNDKEEIF 72 Query: 74 PVDVMRKAAQLGFGGVYIQTDVGGSGLSRLDTSVIFEALATGCTSTTAYISIHN---MCA 130 D +K ++ G G I GG L L T+ + L GC +++ C Sbjct: 73 NRDAWQKCSEFGVHGWPIPARYGGQELDILTTAYALQGLGYGCKDNGLIFAMNAHIWACE 132 Query: 131 WMIDSFGNEEQRHKFCPPLCTMEKFASYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKA 190 + +FG EEQ+ K+ P LC AS+ TEP +GSD SL T+A+K GD YILNG K Sbjct: 133 MPLLTFGTEEQKEKYLPLLCRGGWIASHAATEPQAGSDIYSLKTTAQKDGDKYILNGYKH 192 Query: 191 FISGAGESDIYVVMCRTGGP--GPKGISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIF 248 +++ +D++++ T P G +G++ ++EK TPGL K K+G + + Sbjct: 193 YVTNGTIADLFIIFA-TIDPSLGKEGLTTFMIEKDTPGLILSKPISKMGMRTAEVPELRL 251 Query: 249 EDCAVPVANRIGSEGQGFLIAVRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEP 308 E+C V ANR+G EG G I + R I + ++G + + + KQFG+ Sbjct: 252 ENCEVSAANRLGEEGTGLAIFNHSMEWERGFILAAAVGTMERLLEQSIRYARSHKQFGQA 311 Query: 309 LASNQYLQFTLADMATRLVAARLMVRNAAVALQEERKDAVALCSMAKLFATDECFAICNQ 368 + Q + L +M RL A+ + A ++E ++ A+ SMA L+ ++ C + Sbjct: 312 IGKFQLVANKLVEMKLRLENAKAYLYKVAW-MKENKQMALLEASMANLYISEAWVQSCLE 370 Query: 369 ALQMHGGYGYLKDYAVQQYVRDSRVHQILEGSNEVMRILISRSL 412 A+++HG YGYL + +++ +RD+ + G++E+ R++I++ L Sbjct: 371 AIEIHGAYGYLTNTELERELRDAIASKFYSGTSEIQRVVIAKFL 414 >3B96-A nrPDB Length = 587 Score = 191 bits (485), Expect = 5e-49, Method: Compositional matrix adjust. Identities = 119/384 (30%), Positives = 197/384 (51%), Gaps = 12/384 (3%) Query: 37 PSMGLNEEQKEFQKVAFDFAAR--EMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTD 94 PS+ LNEEQ +F K + +R E + A+ D E+ + +LG G+ + ++ Sbjct: 23 PSV-LNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSE 81 Query: 95 VGGSGLSRLDTSVIFEALATGCTSTTAYISIHNMCAWM-IDSFGNEEQRHKFCPPLCTME 153 +GG GL + + E + + H + I FG + Q+ K+ P L + E Sbjct: 82 LGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGE 141 Query: 154 KFASYCLTEPGSGSDAASLLTSAKKQ--GDHYILNGSKAFISGAGESDIYVVMCRTGGPG 211 A++CLTEP SGSDAAS+ TSA G +Y LNGSK +IS G +DI+ V +T Sbjct: 142 TVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTD 201 Query: 212 P------KGISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQG 265 P + I+ VVE+G G++ G EKK+G + T V F+ VP N +G G G Sbjct: 202 PATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSG 261 Query: 266 FLIAVRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATR 325 F +A+ LN GR +A+ G + DH R QFGE + + +Q LA M Sbjct: 262 FKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVML 321 Query: 326 LVAARLMVRNAAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQ 385 M + + + D +++K+F ++ + + ++ +Q+ GG G++K+ V+ Sbjct: 322 QYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVE 381 Query: 386 QYVRDSRVHQILEGSNEVMRILIS 409 + +RD R+ +I EG+N+++R+ ++ Sbjct: 382 RVLRDLRIFRIFEGTNDILRLFVA 405 >5AHS-A nrPDB Length = 401 Score = 184 bits (468), Expect = 5e-47, Method: Compositional matrix adjust. Identities = 123/381 (32%), Positives = 194/381 (50%), Gaps = 11/381 (2%) Query: 41 LNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGL 100 L EQ+ Q A + A A + D E +P D + + GF G+ + T VGG GL Sbjct: 4 LTPEQRTLQTQARELAQSVFASTAVQTDLTEQYPWDNVAQLRDAGFMGMMLPTSVGGRGL 63 Query: 101 SRLDTSVIFEALATGCTSTTAYISIHNMCAW-MIDSFGNEEQRHKFCPPLCTMEKFASYC 159 S LDT ++ E +A C + N+ A I +G+EEQ K L + C Sbjct: 64 STLDTVIVIEEMAKACATMGRITVDSNLGAIGAITKYGSEEQ-IKLAADLVLAGDKPAIC 122 Query: 160 LTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGGPG-PKGISCI 218 ++EP +GS A+ + T A K GDHYILNG K +I+G G S ++++ R G +GI Sbjct: 123 ISEPNAGSAASEMTTRADKNGDHYILNGEKYWITGGGVSKLHLIFARVFDDGVEQGIGAF 182 Query: 219 VV---EKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIG-SEG--QGFLIAVRG 272 + + G GL G++ +G P + F D + + I +G +GF + Sbjct: 183 ITVLDDHGPEGLKVGRRLYAMGVRGIPETHLEFHDLKIHKSMMITFPDGLKRGFAALMSA 242 Query: 273 LNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLM 332 N R+ + +LG A + +L R+QFG PLA Q LQ+ +ADM+ +L AARLM Sbjct: 243 YNAQRVGAGAVALGIAQCAFEEGVAYLKRREQFGRPLAEFQGLQWMVADMSVQLEAARLM 302 Query: 333 VRNAAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSR 392 +R+AAV+ E + + AK+FA + + N ALQ G GY + ++++VRD+R Sbjct: 303 LRSAAVS--GETFPDINKAAQAKIFAAETANKVTNDALQFFGSSGYGRHNPMERHVRDAR 360 Query: 393 VHQILEGSNEVMRILISRSLL 413 + I G+ +++R ++ +L Sbjct: 361 MFTIAGGTAQILRTQVASKIL 381 >3MPI-A nrPDB Length = 397 Score = 184 bits (468), Expect = 5e-47, Method: Compositional matrix adjust. Identities = 117/379 (30%), Positives = 206/379 (54%), Gaps = 7/379 (1%) Query: 41 LNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVD-VMRKAAQLGFGGVYIQTDVGGSG 99 L++E + QK +F +++ P +WD + FP + +R +LGF G I + GG G Sbjct: 5 LSKELQMLQKEVRNFVNKKIVPFADQWDNENHFPYEEAVRPMGELGFFGTVIPEEYGGEG 64 Query: 100 LSR--LDTSVIFEALATGCTSTTAYISIHNM-CAWMIDSFGNEEQRHKFCPPLCTMEKFA 156 + + L ++ E +A G ++ +++ + CA+ I ++G+E + K+ P L + E Sbjct: 65 MDQGWLAAMIVTEEIARGSSALRVQLNMEVLGCAYTILTYGSEALKKKYVPKLSSAEFLG 124 Query: 157 SYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTG-GPGPKGI 215 + +TEP +GSD ++ ++A+ +GDH++LNGSK +IS A ++D+ + T G +G+ Sbjct: 125 GFGITEPDAGSDVMAMSSTAEDKGDHWLLNGSKTWISNAAQADVLIYYAYTDKAAGSRGL 184 Query: 216 SCIVVE-KGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLN 274 S V+E + PG+ EK +G ++ PT + ++ VP N +G G G I LN Sbjct: 185 SAFVIEPRNFPGIKTSNLEK-LGSHASPTGELFLDNVKVPKENILGKPGDGARIVFGSLN 243 Query: 275 GGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVR 334 R++ A+ +G A A + + N R+QFG+P+ Q Q +A MA + AARL+ Sbjct: 244 HTRLSAAAGGVGLAQACLDAAIKYCNERRQFGKPIGDFQMNQDMIAQMAVEVEAARLLAY 303 Query: 335 NAAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVH 394 AA A E R + +MAK A + N A+++ G YGY +Y V ++ RD+ + Sbjct: 304 KAAAAKDEGRLNNGLDVAMAKYAAGEAVSKCANYAMRILGAYGYSTEYPVARFYRDAPTY 363 Query: 395 QILEGSNEVMRILISRSLL 413 ++EGS + +++I+ L Sbjct: 364 YMVEGSANICKMIIALDQL 382 >5JSC-A nrPDB Length = 410 Score = 165 bits (417), Expect = 3e-41, Method: Compositional matrix adjust. Identities = 95/279 (34%), Positives = 156/279 (55%), Gaps = 4/279 (1%) Query: 137 GNEEQRHKFCPPLCTMEKFASYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAG 196 G EQ+ ++ P + A++ L+EP +GSD A++ SA++ GD Y+L+G K +IS G Sbjct: 123 GTHEQKTRYLPRVANGTAIAAFALSEPEAGSDVAAMTLSAREDGDAYVLDGDKTWISNGG 182 Query: 197 ESDIYVVMCRTG-GPGPKGISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPV 255 +D YVV RTG PG +GIS VV+ TPGL ++ + P + F VP Sbjct: 183 IADFYVVFARTGEAPGARGISAFVVDADTPGLEIAERIDVIA--PHPLARLHFAGARVPR 240 Query: 256 ANRIGSEGQGFLIAVRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYL 315 + +G+ G+GF +A+R L+ R ++A+ SLG A ++ RK FG+ L Q Sbjct: 241 SQMLGAPGEGFKLAMRTLDIFRTSVAAASLGFARHAMAEGVARAASRKMFGQTLGDFQLT 300 Query: 316 QFTLADMATRLVAARLMVRNAAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGG 375 Q LA MA + ++ L+V AA L+++ ++ +MAK A++ + + A+Q++GG Sbjct: 301 QAKLAQMALTIDSSALLVYRAAW-LRDQGENVTREAAMAKWHASEGAQQVIDAAVQLYGG 359 Query: 376 YGYLKDYAVQQYVRDSRVHQILEGSNEVMRILISRSLLQ 414 G AV+ R+ R +I EG+ EV ++++ R LL+ Sbjct: 360 MGVQSGTAVEMLYREIRALRIYEGATEVQQLIVGRDLLK 398 >5IDU-A nrPDB Length = 410 Score = 162 bits (411), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 114/377 (30%), Positives = 194/377 (51%), Gaps = 19/377 (5%) Query: 53 FDFAAREMAPNMAEWDQKELFPVD------VMRKAAQ-LGFGGVYIQTDVGGSGL----S 101 F+ RE+A + W + L V RK + LG G +++ VGG+ Sbjct: 26 FEARHRELAAGIEAWATQHLACVQHDDTDTTCRKLVRALGEAG-WLKYGVGGAQYGGHGD 84 Query: 102 RLDTS---VIFEALATGCTSTTAYISIHNMCAWMIDSFGNEEQRHKFCPPLCTMEKFASY 158 +DT ++ E LA +++ + + I G EQ+ ++ P + E A++ Sbjct: 85 TIDTRAVCLLRETLANHDGLADFALAMQGLGSGAITLAGTHEQKIRYLPRVSKGEAIAAF 144 Query: 159 CLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTG-GPGPKGISC 217 L+EP +GSD A++ A+ +GD Y+++G K +IS G +D YVV RTG PG +GIS Sbjct: 145 ALSEPDAGSDVAAMSLQARAEGDCYVIDGDKTWISNGGIADFYVVFARTGEAPGARGISA 204 Query: 218 IVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGGR 277 +V+ TPGL ++ + P + F+ VP + +G+ G+GF IA+R L+ R Sbjct: 205 FIVDADTPGLQIAERIDVIA--PHPLARLHFDSARVPRSQMLGAPGEGFKIAMRTLDVFR 262 Query: 278 INIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNAA 337 ++A+ SLG A ++ RK FG+ L Q Q LA MA + ++ L+V AA Sbjct: 263 TSVAAASLGFARRALQEGLARAASRKMFGQTLGDFQLTQTKLAQMALTIDSSALLVYRAA 322 Query: 338 VALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQIL 397 L+++ ++ +MAK A++ + + A+Q+ GG G V++ R+ R +I Sbjct: 323 W-LRDQGENVTREAAMAKWHASEGAQQVIDAAVQLWGGMGVQSGTTVERLYREIRALRIY 381 Query: 398 EGSNEVMRILISRSLLQ 414 EG+ EV ++++ R LL+ Sbjct: 382 EGATEVQQLIVGRDLLK 398 >6CY8-B nrPDB Length = 380 Score = 157 bits (398), Expect = 5e-39, Method: Compositional matrix adjust. Identities = 114/377 (30%), Positives = 181/377 (48%), Gaps = 13/377 (3%) Query: 43 EEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVG--GSGL 100 EQ E + A F AP + FP D G+ G+ I GSG Sbjct: 7 HEQAELFEHALRFGKELSAP----LQEDNGFPRDNWNALGDFGYFGLPIPEKYAKDGSGF 62 Query: 101 SRLDTSVIFEALATGCTSTTAYIS--IHNM-CAWMIDSFGNEEQRHKFCPPLCTMEKFAS 157 L T I E L CT T + H C+ I G+E +H+ P L T K A+ Sbjct: 63 DILTTIKIIEGLGQSCTDTGLLFAGAAHTFACSMPILEHGSETLKHQLLPDLATGRKIAA 122 Query: 158 YCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGGP-GPKGIS 216 ++E +GSD ++L T+A+K+GD+Y+LNG K++++ +D YVV T G G + Sbjct: 123 NAISEASAGSDISNLATTAQKEGDYYVLNGGKSYVTNGSIADYYVVYATTNKKHGYLGQT 182 Query: 217 CIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGG 276 VV + TPG+S G K+G S P V F++C + +G EGQG I ++ Sbjct: 183 AFVVPRNTPGISVGNDYHKLGLRSAPLNQVFFDNCTIHKDYALGREGQGARIFAASMDWE 242 Query: 277 RINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNA 336 R + + +GA + ++ N R Q + ++ Q + +ADM RL +ARLM+ A Sbjct: 243 RCCLFAIFVGAMQRDLNQCIEYANTRMQGDKTISRFQAVSHRIADMGVRLESARLMLYYA 302 Query: 337 AVALQEERKDAVALCSMAKLFATDECFAICN-QALQMHGGYGYLKDYAVQQYVRDSRVHQ 395 A ++ + A+ +M+KL A E F ++++HG GYL + V ++D+ Sbjct: 303 AWQKSQDVDNTKAV-AMSKL-AISEAFVQSGIDSIRVHGALGYLDEGRVNNSIKDALGSV 360 Query: 396 ILEGSNEVMRILISRSL 412 + G++++ R LI L Sbjct: 361 LFSGTSDIQRELICNRL 377 >6ES9-A nrPDB Length = 551 Score = 156 bits (395), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 111/389 (28%), Positives = 195/389 (50%), Gaps = 15/389 (3%) Query: 38 SMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKE-LFPVDVMRKAAQLGFGGVYIQTDVG 96 + GL+E+ + + +A + PN EW K+ L P++++ + A+LG G+ I + G Sbjct: 164 ATGLDEDLEMIRDQFRRYAEERVIPNAHEWHLKDQLIPMEIIEELAELGVFGLTIPEEFG 223 Query: 97 GSGLSRLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSFGNEEQRHKFCPPLCTMEKFA 156 G GLS+ V+ E L+ G + + + A +I G E Q+ K+ P L + E + Sbjct: 224 GLGLSKASMVVVTEELSRGYIGVGSLGTRSEIAAELILCGGTEAQKAKWLPGLASGEILS 283 Query: 157 SYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGGPGP--KG 214 + TEP +GSD SL T A + G+ +++ G+K +I+ A + + ++ RT +G Sbjct: 284 TAVFTEPNTGSDLGSLRTRAVRDGEDWVVTGNKTWITHAQRTHVMTLLARTDPETTDWRG 343 Query: 215 ISCIVVEK---------GTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSE-GQ 264 +S + EK TPG++ G+ E +G+ + F+ + N +G E G+ Sbjct: 344 LSMFLAEKEPGTDDDPFPTPGMTGGEIE-VLGYRGMKEYELGFDGFRIKGENLLGGEPGR 402 Query: 265 GFLIAVRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMAT 324 GF + RI A+ ++G A ++ + + RKQFG+ L + LA MA Sbjct: 403 GFKQLMETFESARIQTAARAVGVAQSAAEIGMRYAVDRKQFGKSLIEFPRVADKLAMMAV 462 Query: 325 RLVAARLMVRNAAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAV 384 ++ AR + +A R+ + MAKL +A + ALQ+HGG G+ +YA+ Sbjct: 463 EIMIARQLTYFSAWEKDHGRRCDLE-AGMAKLLGARVAWAAADNALQIHGGNGFALEYAI 521 Query: 385 QQYVRDSRVHQILEGSNEVMRILISRSLL 413 + + D+R+ I EG+ E+ +I+R LL Sbjct: 522 SRVLCDARILNIFEGAAEIQAQVIARRLL 550 >3GNC-A nrPDB Length = 399 Score = 151 bits (381), Expect = 6e-37, Method: Compositional matrix adjust. Identities = 106/372 (28%), Positives = 182/372 (48%), Gaps = 3/372 (0%) Query: 41 LNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGL 100 L ++++ + A +A ++AP + E + E + R+ ++G G I GG GL Sbjct: 22 LADDERMVRDAAHAYAQGKLAPRVTEAFRHETTDAAIFREMGEIGLLGPTIPEQYGGPGL 81 Query: 101 SRLDTSVIFEALATGCTSTTAYISIHNMCAWM-IDSFGNEEQRHKFCPPLCTMEKFASYC 159 + +I + + + +S+ + + I FG++ Q+ K+ P L T E + Sbjct: 82 DYVSYGLIAREVERVDSGYRSMMSVQSSLVMVPIFEFGSDAQKEKYLPKLATGEWIGCFG 141 Query: 160 LTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGGPGPKGISCIV 219 LTEP GSD S++T A+K Y L+GSK +I+ + +D++VV + G I + Sbjct: 142 LTEPNHGSDPGSMVTRARKVPGGYSLSGSKMWITNSPIADVFVVWAKLDEDGRDEIRGFI 201 Query: 220 VEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGGRIN 279 +EKG GLS KVG + T ++ ++ VP N I +G LN R Sbjct: 202 LEKGCKGLSAPAIHGKVGLRASITGEIVLDEAFVPEEN-ILPHVKGLRGPFTCLNSARYG 260 Query: 280 IASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNAAVA 339 IA +LGAA + + R ++ RKQFG PLA+NQ +Q LADM T + V Sbjct: 261 IAWGALGAAESCWHIARQYVLDRKQFGRPLAANQLIQKKLADMQTEITLGLQGVLRLG-R 319 Query: 340 LQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQILEG 399 +++E AV + S+ K + + I A M GG G ++ V +++ + V EG Sbjct: 320 MKDEGTAAVEITSIMKRNSCGKALDIARLARDMLGGNGISDEFGVARHLVNLEVVNTYEG 379 Query: 400 SNEVMRILISRS 411 ++++ +++ R+ Sbjct: 380 THDIHALILGRA 391 >5ZW7-A nrPDB Length = 402 Score = 147 bits (372), Expect = 6e-36, Method: Compositional matrix adjust. Identities = 104/376 (27%), Positives = 189/376 (50%), Gaps = 5/376 (1%) Query: 41 LNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGL 100 L+ Q + + A+ FA + + +++ ++ +KAA GF + GGS L Sbjct: 5 LSNSQSDIYESAYRFACDVLDQDAQTRISQKILSTELWKKAAAYGFAHGPVSHQFGGSEL 64 Query: 101 SRLDTSVIFEALATGCTSTTAYISI-HNMCAWMID--SFGNEEQRHKFCPPLCTMEKFAS 157 LDT+++ EAL G S+ ++CA +I FG+ E + K+ L T + A+ Sbjct: 65 GALDTALMIEALGKGSRDIGLSFSLCAHLCACVIPLYRFGSSELKDKYLESLVTGKLIAA 124 Query: 158 YCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTG-GPGPKGIS 216 TEP +GSD ++ +A+ YILNG K FI+ A +D++++ +T G G+S Sbjct: 125 NAATEPDAGSDIYNMQATAQPCEGGYILNGKKIFITNAPIADVFIIYAKTNPDHGFLGVS 184 Query: 217 CIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGG 276 ++EKGTPGL+ G+ K ++ P ++F D +P + RIG EG G I + Sbjct: 185 AFLIEKGTPGLNVGEVIPKDCLSNCPWSEIVFNDIFIPQSQRIGMEGAGGAIFHDSMIWE 244 Query: 277 RINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNA 336 + +++ +G + T ++ R+QFG+ + Q + + DM RL RLM+ A Sbjct: 245 KGCLSALFVGGLARLLETTLEYAKARQQFGKAIGQFQSVSNRIIDMKLRLEQCRLMLYRA 304 Query: 337 AVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQI 396 ++ +DA A +M+KL ++ A+Q GG ++ + +++ + +I Sbjct: 305 CWK-HDQGQDAEADIAMSKLLISEYAVQSGLDAIQTFGGAAMDQELGLVRHLLNMIPSRI 363 Query: 397 LEGSNEVMRILISRSL 412 G+N++ + +I+R L Sbjct: 364 FSGTNDIQKEIIARKL 379 >2EBA-A nrPDB Length = 385 Score = 135 bits (340), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 98/374 (26%), Positives = 180/374 (48%), Gaps = 7/374 (1%) Query: 41 LNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGL 100 L E+KE QK A F +E P++ +W ++ +FP ++ + A+LGF G + + GG+G+ Sbjct: 11 LTPEEKEVQKAARRFLEKEALPHIRDWWEEGVFPTHLIPRFAELGFLGPTLPPEYGGAGV 70 Query: 101 SRLDTSVIFEALATGCTSTTAYISIH-NMCAWMIDSFGNEEQRHKFCPPLCTMEKFASYC 159 S +I L + +++S+ ++ + I ++G+EEQ+ +F P L E + Sbjct: 71 SSAAYGLICYELERVDSGLRSFVSVQSSLVMYPIYAYGSEEQKREFLPKLARGEMVGCFG 130 Query: 160 LTEPGSGSDA-ASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGGPGPKGISCI 218 LTEP GSD ++ T A+++GD ++LNG+K +I+ + + V+ + G + Sbjct: 131 LTEPDGGSDPYGNMKTRARREGDTWVLNGTKMWITNGNLAHLAVIWAKDEG---GEVLGF 187 Query: 219 VVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGGRI 278 +V TPG + ++K+ + T ++ E+ VP + R+ + G + L R Sbjct: 188 LVPTDTPGFQAREVKRKMSLRASVTSELVLEEVRVPESLRL-PKALGLKAPLSCLTQARF 246 Query: 279 NIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNAAV 338 IA ++GA A R FGEPLA Q +Q LA+M ++ Sbjct: 247 GIAWGAMGALEAVYEEAVAFAKSRSTFGEPLAKKQLVQAKLAEMLAWHTEGL-LLAWRLA 305 Query: 339 ALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQILE 398 L++E K A S+AK + A + GG G +Y +++ + E Sbjct: 306 RLKDEGKLTPAQVSLAKRQNVWKALQAARMARDILGGSGITLEYHAIRHMLNLETVYTYE 365 Query: 399 GSNEVMRILISRSL 412 G+++V +++ R + Sbjct: 366 GTHDVHTLVLGREI 379 >3SF6-A nrPDB Length = 403 Score = 125 bits (314), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 99/380 (26%), Positives = 178/380 (46%), Gaps = 21/380 (5%) Query: 41 LNEEQKEFQKVAFDFAAREMAPNMAEW-DQKELFPVDVMRKAAQLGFGGVYIQTDVGGSG 99 L+ E++E + R + P++A W + EL ++ + +LG G++++ G +G Sbjct: 30 LSAEEREIRDTVRSVVQRRIKPHIASWYEDGELPARELAVELGELGLLGMHLK-GYGCAG 88 Query: 100 LSRLDTSVIFEALATGCTSTTAYISIH-NMCAWMIDSFGNEEQRHKFCPPLCTMEKFASY 158 +S + + L G + + +S+ ++ + I +FG++EQ+ ++ P + + + + Sbjct: 89 MSAVAYGLACLELEAGDSGIRSLVSVQGSLAMYAIHAFGSDEQKDQWLPDMASGHRIGCF 148 Query: 159 CLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGGPGPKGISCI 218 LTEP GSD A + T A + GD +IL G+K +I+ +D+ VV RT +GI Sbjct: 149 GLTEPDHGSDPAGMRTRATRSGDDWILTGTKMWITNGSVADVAVVWART----DEGIRGF 204 Query: 219 VVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRI-GSEGQGFLIAVRGLNGGR 277 VV TPG + + K+ + T ++ + +P + R+ G+ G +R LN R Sbjct: 205 VVPTDTPGFTANTIKSKMSLRASVTSELVLDGVRLPDSARLPGATSLG--APLRCLNEAR 262 Query: 278 INIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATR-----LVAARLM 332 I +LGAA + + R+QF P+ Q Q LADM L+A L Sbjct: 263 FGIVFGALGAARDCLETALAYACSREQFDRPIGGFQLTQQKLADMTLEYGKGFLLALHLG 322 Query: 333 VRNAAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSR 392 + A L E+ S+ KL E I A + G G +Y V ++ + Sbjct: 323 RQKDAGELAPEQ------VSLGKLNNVREAIEIARTARTVLGASGITGEYPVMRHANNLE 376 Query: 393 VHQILEGSNEVMRILISRSL 412 EG++E+ ++I ++L Sbjct: 377 SVLTYEGTSEMHTLIIGQAL 396 >4W9U-A nrPDB Length = 395 Score = 125 bits (313), Expect = 4e-29, Method: Compositional matrix adjust. Identities = 107/377 (28%), Positives = 176/377 (46%), Gaps = 14/377 (3%) Query: 41 LNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGL 100 L E+++ + A FA+ + P + + +E ++ Q G GV + D G + Sbjct: 19 LTEDERMIRDSAKAFASDVLLPRVEKAYLEETTDPELFHLMGQAGLLGVTLPEDYGAANA 78 Query: 101 SRLDTSVI---FEALATGCTSTTAYISIHNMCAWMIDSFGNEEQRHKFCPPLCTMEKFAS 157 S + ++ E + +G S + S ++ + I ++G++EQR K+ P L + E Sbjct: 79 SYVAYGLVAREVERIDSGYRSMMSVQS--SLVMYPIYAYGSDEQRKKYLPGLVSGELIGC 136 Query: 158 YCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGGPGPKGISC 217 + LTEP +GSD A + T A+K Y L+GSK +IS + +D++VV ++ I Sbjct: 137 FGLTEPDAGSDPAGMKTRAEKIDGGYRLSGSKMWISNSPIADVFVVWAKSAAH-DNAIRG 195 Query: 218 IVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGGR 277 ++EKG GLS K K+ + T ++ + V + I G LN R Sbjct: 196 FILEKGMKGLSAPKIGGKLSLRASITGEIVMDGVEVS-EDAILPNVSGLKGPFGCLNRAR 254 Query: 278 INIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRL---VAARLMVR 334 I+ LGAA R + RKQF +PLA Q Q LADM T + + A L V Sbjct: 255 YGISWGVLGAAEDCWFRARQYGLDRKQFNKPLAGTQLYQKKLADMQTEIALGIQASLRVG 314 Query: 335 NAAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVH 394 L +E K A + S+ K + I QA MHGG G +Y V ++ ++ Sbjct: 315 R----LFDEGKMAPEMISIVKRNNCGKALDIARQARDMHGGNGIQIEYHVMRHAQNLETV 370 Query: 395 QILEGSNEVMRILISRS 411 EG+++V +++ R+ Sbjct: 371 NTYEGTHDVHALILGRA 387 >3SWO-A nrPDB Length = 399 Score = 123 bits (309), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 92/378 (24%), Positives = 180/378 (47%), Gaps = 18/378 (4%) Query: 41 LNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGL 100 L++++++ F + PN+ W + P ++ ++ LG G+++Q G +G Sbjct: 26 LDQDERDIAATVRQFVDTRLKPNVEGWFESATLPSELAKEFGNLGVLGMHLQ-GYGCAGT 84 Query: 101 SRLDTSVIFEALATGCTSTTAYISIH-NMCAWMIDSFGNEEQRHKFCPPLCTMEKFASYC 159 + + + L G + +++S+ ++ + I +G+EEQ++++ P L + + Sbjct: 85 NAVSYGLACMELEAGDSGFRSFVSVQGSLSMFSIYRYGSEEQKNEWLPRLAAGDAIGCFG 144 Query: 160 LTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGGPGPKGISCIV 219 LTEP GS+ A + T A++ G +ILNG+K +I+ +D+ V +T GI + Sbjct: 145 LTEPDFGSNPAGMRTRARRDGSDWILNGTKMWITNGNLADVATVWAQT----DDGIRGFL 200 Query: 220 VEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGGRIN 279 V TPG + + +K+ + T ++ ++ +P + ++ +G + LN R Sbjct: 201 VPTDTPGFTANEIHRKLSLRASVTSELVLDNVRLPASAQL-PLAEGLSAPLSCLNEARFG 259 Query: 280 IASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNAAVA 339 I +LGAA S+ T + R+ F +PL++ Q Q LA+M L L+ A Sbjct: 260 IVFGALGAARDSLETTIAYTQSREVFDKPLSNYQLTQEKLANMTVELGKGMLL------A 313 Query: 340 LQEER-KDAVAL----CSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVH 394 + R KDA + S+ KL E AI + + GG G +Y+ ++ + Sbjct: 314 IHLGRIKDAEGVRPEQISLGKLNNVREAIAIARECRTLLGGSGITLEYSPLRHANNLESV 373 Query: 395 QILEGSNEVMRILISRSL 412 EG++E+ + I ++L Sbjct: 374 LTYEGTSEMHLLSIGKAL 391 >1SIR-A nrPDB Length = 394 Score = 120 bits (302), Expect = 7e-28, Method: Compositional matrix adjust. Identities = 100/362 (27%), Positives = 172/362 (47%), Gaps = 11/362 (3%) Query: 55 FAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGLSRLDTSVIFEALAT 114 + + P + ++ E+F +++ + +LG G I+ G +G+S + ++ L Sbjct: 30 YCQERLMPRILLANRNEVFHREIISEMGELGVLGPTIK-GYGCAGVSSVAYGLLARELER 88 Query: 115 GCTSTTAYISIHN-MCAWMIDSFGNEEQRHKFCPPLCTMEKFASYCLTEPGSGSDAASLL 173 + + +S+ + + I ++G+EEQR K+ P L E + LTEP SGSD +S+ Sbjct: 89 VDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSME 148 Query: 174 TSAKKQGDH--YILNGSKAFISGAGESDIYVVMCRTGGPGPKGISCIVVEKGTPGLSFGK 231 T A + Y LNG+K +I+ + +D++VV R +G ++EKG GLS + Sbjct: 149 TRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGCIRG---FLLEKGMRGLSAPR 205 Query: 232 KEKKVGWNSQPTRAVIFEDCAVPVANRI-GSEGQGFLIAVRGLNGGRINIASCSLGAAHA 290 + K + T +I + VP N + G+ G LN R IA LGA+ Sbjct: 206 IQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGGPFGC--LNNARYGIAWGVLGASEF 263 Query: 291 SVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNAAVALQEERKDAVAL 350 + R + R QFG PLA NQ +Q LADM T + L L+++ K A + Sbjct: 264 CLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLG-LHACLQLGRLKDQDKAAPEM 322 Query: 351 CSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQILEGSNEVMRILISR 410 S+ K + I QA M GG G +Y V ++ + EG++++ +++ R Sbjct: 323 VSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGR 382 Query: 411 SL 412 ++ Sbjct: 383 AI 384 >2IX5-A nrPDB Length = 436 Score = 114 bits (284), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 95/373 (25%), Positives = 166/373 (44%), Gaps = 6/373 (1%) Query: 41 LNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGL 100 L E++ +K + +E+AP M E+ +K FP + K +G G I+ G GL Sbjct: 55 LTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSIK-GYGCPGL 113 Query: 101 SRLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSF-GNEEQRHKFCPPLCTMEKFASYC 159 S ++ +A S + +I +H+ + + G+E Q+ K+ P L + A + Sbjct: 114 SITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWA 173 Query: 160 LTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGGPGPKGISCIV 219 LTEP +GSDA+ L T+A K + +NG K +I + +D+ ++ R I+ + Sbjct: 174 LTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFARNT--TTNQINGFI 231 Query: 220 VEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGGRIN 279 V+K PGL K K+G ++ ++ VP +R+ F + L R+ Sbjct: 232 VKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGV-NSFQDTSKVLAVSRVM 290 Query: 280 IASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNAAVA 339 +A +G + + +L RKQFG PLA+ Q Q L M + A LM Sbjct: 291 VAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRLC-K 349 Query: 340 LQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQILEG 399 L E + S+ K + + + + ++ GG G L D+ V + D EG Sbjct: 350 LYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTYEG 409 Query: 400 SNEVMRILISRSL 412 + ++ ++ R + Sbjct: 410 TYDINTLVTGREV 422 >1R2J-A nrPDB Length = 366 Score = 104 bits (259), Expect = 8e-23, Method: Compositional matrix adjust. Identities = 87/351 (24%), Positives = 155/351 (44%), Gaps = 7/351 (1%) Query: 65 AEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGLSRLDTSVIFEALATGCTSTTAYIS 124 AEWD P D++ + G + + GG GL + + + C+S + ++ Sbjct: 17 AEWDTSGELPRDLLVRLGADGLLCAEVAAEHGGLGLGSRENGEFTAHVGSLCSSLRSVMT 76 Query: 125 IHNMCAWMIDSFGNEEQRHKFCPPLCTMEKFASYCLTEPGSGSDAASLLTSAKKQGDHYI 184 M AW + G+ QR F L T K A+ +E +GSD +++ T + GD + Sbjct: 77 SQGMAAWTVQRLGDAGQRATFLKEL-TSGKLAAVGFSERQAGSDLSAMRTRVRLDGDTAV 135 Query: 185 LNGSKAFISGAGESDIYVVM-CRTGGPGPKGISCIVVEKGTPGLSFGKKEKKVGWNSQPT 243 ++G K + + A +D VV + G G + +VV TPG+ + K G + Sbjct: 136 VDGHKVWTTAAAYADHLVVFGLQEDGSG----AVVVVPADTPGVRVERVPKPSGCRAAGH 191 Query: 244 RAVIFEDCAVPVANRIGSEGQGF-LIAVRGLNGGRINIASCSLGAAHASVILTRDHLNVR 302 + + VP + G ++ L GR ++A +G A H R Sbjct: 192 ADLHLDQVRVPAGAVLAGSGASLPMLVAASLAYGRKSVAWGCVGILRACRTAAVAHARTR 251 Query: 303 KQFGEPLASNQYLQFTLADMATRLVAARLMVRNAAVALQEERKDAVALCSMAKLFATDEC 362 +QFG PL +Q + +AD+ T A + A+ E + V +AK A + Sbjct: 252 EQFGRPLGDHQLVAGHIADLWTAEQIAARVCEYASDHWDEGSPEMVPATILAKHVAAERA 311 Query: 363 FAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQILEGSNEVMRILISRSLL 413 A A Q+ G + + V++ RD+++ +I+EGS+E+ R+++++ L Sbjct: 312 AAGAATAAQVLASAGAREGHVVERAYRDAKLMEIIEGSSEMCRVMLAQHAL 362 >4HR3-A nrPDB Length = 415 Score = 99.0 bits (245), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 89/345 (25%), Positives = 165/345 (47%), Gaps = 18/345 (5%) Query: 80 KAAQLGFGGVYIQTDVGGSGLSRLDTSVIFEALATGCTSTTAY----ISIHNMCAWMIDS 135 KA G +++ G GLS + + + E + + T + NM ++ Sbjct: 66 KARAAGLWNLFLPDPELGGGLSNSEYAPLAEQMGRSLFAPTVFNCNAPDSGNME--VLHR 123 Query: 136 FGNEEQRHKFCPPLCTMEKFASYCLTEPG-SGSDAASLLTSAKKQGDHYILNGSKAFISG 194 +G++EQ+ + PL + +++C+TEP + SDA ++ +A +GD ++NG K + +G Sbjct: 124 YGSQEQKEVWLEPLLEGDIRSAFCMTEPDVASSDATNMAATAVVEGDEVVINGRKWWSTG 183 Query: 195 AGESDIYVVMCRTGGPGPKGI-----SCIVVEKGTPGLSFGKKEKKVGWNSQP--TRAVI 247 G D V++ G P S ++V TPG++ + +G+ +P V Sbjct: 184 VGHPDCKVIIF-MGLTDPNAHRYARHSMVLVPMDTPGITVERMLPTMGFYDEPGGHGVVS 242 Query: 248 FEDCAVPVANRIGSEGQGFLIAVRGLNGGRINIASCSLGAAHASVILT-RDHLNVRKQFG 306 F++ +P I G+GF IA L GR++ A +G A ++ R L+ R FG Sbjct: 243 FDNVRLPADAFIAGPGKGFEIAQGRLGPGRVHHAMRLIGLAEVALEHACRRGLD-RTAFG 301 Query: 307 EPLASNQYLQFTLADMATRLVAARLMVRNAAVALQEER-KDAVALCSMAKLFATDECFAI 365 +PL + + +AD + RL+V +AA L A++ S K+ A + + Sbjct: 302 KPLVNLGGNRERIADARIAINQTRLLVLHAAWLLDTVGIMGALSAVSEIKVAAPNMAQQV 361 Query: 366 CNQALQMHGGYGYLKDYAVQQYVRDSRVHQILEGSNEVMRILISR 410 + A+Q+HGG G D+ + ++R ++ +G +EV R +++R Sbjct: 362 IDMAIQIHGGGGLSNDFPLAAAWVNARALRLADGPDEVHRGVVAR 406 >4X28-A nrPDB Length = 400 Score = 98.6 bits (244), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 107/389 (27%), Positives = 175/389 (44%), Gaps = 32/389 (8%) Query: 44 EQKEFQKVAFDFAAREMAPNMAEW---DQKELFPVDVMRKA-AQLGFGG---VYIQTDVG 96 +Q+E ++ + A M P E Q E +V R+ AQ+G G + + G Sbjct: 8 QQEELRRELRSYFATLMTPERREALSSVQGEYGVGNVYRETIAQMGRDGWLALGWPKEYG 67 Query: 97 GSGLSRLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSFGNEEQRHKFCPPLCTMEKFA 156 G G S +D +IF A + +++I N A I ++G +EQ+ F P + + Sbjct: 68 GQGRSAMD-QLIFTDEAAIAGAPVPFLTI-NSVAPTIMAYGTDEQKRFFLPRIAAGDLHF 125 Query: 157 SYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRT-----GGPG 211 S +EPG+G+D A+L T+A + GD Y++NG K + S +D + RT G Sbjct: 126 SIGYSEPGAGTDLANLRTTAVRDGDDYVVNGQKMWTSLIQYADYVWLAVRTNPESSGAKK 185 Query: 212 PKGISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVR 271 +GIS ++V G S+ G T A + D VPVANR+G E G+ + Sbjct: 186 HRGISVLIVPTTAEGFSWTPVHTMAG---PDTSATYYSDVRVPVANRVGEENAGWKLVTN 242 Query: 272 GLNGGRINIASCSLGAAHASVILTRDHL-NVRKQFGEPLASNQYLQFTLADMATRLVAAR 330 LN R+ + S + + R+ N + G L ++++Q LA + + + Sbjct: 243 QLNHERVALVSPA--PIFGCLREVREWAQNTKDAGGTRLIDSEWVQLNLARVHAKAEVLK 300 Query: 331 LMVRNAAVALQEERKDA---VALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQY 387 L+ A + Q KDA A S AK+F T+ +++ G L+ + Sbjct: 301 LINWELASS-QSGPKDAGPSPADASAAKVFGTELATEAYRLLMEVLGTAATLRQNSPGAL 359 Query: 388 VRD--SRVHQ---ILE---GSNEVMRILI 408 +R R+H+ IL G+NEV R +I Sbjct: 360 LRGRVERMHRACLILTFGGGTNEVQRDII 388 >4RM7-A nrPDB Length = 391 Score = 92.0 bits (227), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 89/385 (23%), Positives = 177/385 (45%), Gaps = 17/385 (4%) Query: 40 GLNEEQKEFQKVAFDFAAREMAP-NMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGS 98 GL+ +++ ++ + P ++++W + + P +V++ L F G + Sbjct: 7 GLSRDEQRLLNHVREYGEKYFTPASISKWRKDQGLPDEVVKAFVDLDFNGFGVIHRRNHR 66 Query: 99 GLSRLDTSVIFEALATGCTSTTAYISIHN--MCAWMIDSFGNEEQRHKFCPPLCTMEKFA 156 ++ E L+ + A + N + ++++F + Q F + Sbjct: 67 TYDLFAQVLVIEELSR---ISGACLPFQNDLLQLQILEAFASSAQTSPFRTEYQDTGRL- 122 Query: 157 SYCL--TEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMC--RTGGPGP 212 SY L +EP +GSD S+ T ++GD ++NG+K F++ + +V +TG G Sbjct: 123 SYALAISEPEAGSDTRSMRTHVTREGDTLVMNGTKMFVNNGEYAPALLVSAYDKTGDDGE 182 Query: 213 KGISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRG 272 S +V + G+ + E+K+G + P V F++ V + R+ +GF Sbjct: 183 PEFSFWMVPRSAAGI-YAYPEQKIGQSMLPFATVRFDNVEVKESWRLKGSSKGFSQLYSL 241 Query: 273 LNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLM 332 L GR+ + +LG A A++ R+ FG+ +A Q +Q L +M +L R + Sbjct: 242 LEYGRVFTCAAALGEAQAAMEDAVAWARGREAFGQRIADLQQVQMKLTEMEVKLTNMRNL 301 Query: 333 VRNAAVALQ--EERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRD 390 V AA E ++ +VAL K + + + A+Q+ GG GY+++ V +D Sbjct: 302 VYGAAREYDRGEHKRLSVALM---KYYVPKAATEVASDAMQILGGRGYIQENRVSSIWQD 358 Query: 391 SRVHQILEGSNEVMRILISRSLLQE 415 R +Q +G++EVM ++ + +L++ Sbjct: 359 CRGYQFADGTDEVMVVIAAPLILEQ 383 >2WBI-A nrPDB Length = 428 Score = 90.9 bits (224), Expect = 9e-19, Method: Compositional matrix adjust. Identities = 76/278 (27%), Positives = 131/278 (47%), Gaps = 10/278 (3%) Query: 136 FGNEEQRHKFCPPLCTMEKFASYCLTEPG-SGSDAASLLTSAKKQGDHYILNGSKAFISG 194 +G+EEQ+ ++ PL + +C+TEP + SDA ++ S ++ D Y++NG K + SG Sbjct: 130 YGSEEQKKQWLEPLLQGNITSCFCMTEPDVASSDATNIECSIQRDEDSYVINGKKWWSSG 189 Query: 195 AGESD--IYVVMCRTGGPG---PKGISCIVVEKGTPGLSFGKKEKKVGWNSQ---PTRAV 246 AG I +V+ RT K S I+V TPG+ + G+ + Sbjct: 190 AGNPKCKIAIVLGRTQNTSLSRHKQHSMILVPMNTPGVKIIRPLSVFGYTDNFHGGHFEI 249 Query: 247 IFEDCAVPVANRIGSEGQGFLIAVRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFG 306 F VP N I EG+GF I+ L GRI+ ++G A ++ + + R F Sbjct: 250 HFNQVRVPATNLILGEGRGFEISQGRLGPGRIHHCMRTVGLAERALQIMCERATQRIAFK 309 Query: 307 EPLASNQYLQFTLADMATRLVAARLMVRNAAVALQE-ERKDAVALCSMAKLFATDECFAI 365 + L +++ + +A+ + RL+ AA ++ A +M K+ A I Sbjct: 310 KKLYAHEVVAHWIAESRIAIEKIRLLTLKAAHSMDTLGSAGAKKEIAMIKVAAPRAVSKI 369 Query: 366 CNQALQMHGGYGYLKDYAVQQYVRDSRVHQILEGSNEV 403 + A+Q+ GG G +DY + +RV ++ +G +EV Sbjct: 370 VDWAIQVCGGAGVSQDYPLANMYAITRVLRLADGPDEV 407 >5EZ3-A nrPDB Length = 573 Score = 77.4 bits (189), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 73/265 (27%), Positives = 123/265 (46%), Gaps = 20/265 (7%) Query: 160 LTEPGSGSDAASLLTSAKKQ-GDHYILNGSKAFISGAGESDIYVVMCRTGGPGPKGISCI 218 +TE G+D + T A+ G + L G K F+S A SD ++ + +T +G+SC Sbjct: 213 MTEKQGGTDVRANATRAEPAIGGAWRLTGHKWFMS-APMSDAFLTLAQT----KEGLSCF 267 Query: 219 VV----EKG-TPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGL 273 ++ EKG + G F + + K+G S + V F+ + IGS G+G + + Sbjct: 268 LLPRLGEKGESNGFFFQRLKDKLGNRSNASSEVEFDGA---LGQMIGSPGEGVKTIMDMV 324 Query: 274 NGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMV 333 R++ A S G + + H R FG+PL +Q LADMA + A + Sbjct: 325 TLTRLDCAVASAGLMRSGLAEAVHHSRHRHVFGKPLVEQPLMQRVLADMALDVAGATALS 384 Query: 334 RNAAVALQEERKD------AVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQY 387 A A D A ++ + K + A+ +A++ GG GY++D + + Sbjct: 385 MRLARAFDMAASDRAEAAFARSMTPVVKYWVCKIAPALLYEAMECLGGNGYIEDGNLARA 444 Query: 388 VRDSRVHQILEGSNEVMRILISRSL 412 R++ V+ I EGS VM + ++R L Sbjct: 445 YREAPVNAIWEGSGNVMALDVARVL 469 >3U33-A nrPDB Length = 541 Score = 76.3 bits (186), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 74/266 (27%), Positives = 120/266 (45%), Gaps = 23/266 (8%) Query: 160 LTEPGSGSDAASLLTSAKKQGD-HYILNGSKAFISGAGESDIYVVMCRTGGPGPKGISCI 218 +TE GSD S T A++ D Y L G K F S +SD ++V+ +T G G+SC Sbjct: 184 MTEKQGGSDVMSNTTRAERLEDGSYRLVGHKWFFS-VPQSDAHLVLAQTAG----GLSCF 238 Query: 219 VVEKGTP-----GLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGL 273 V + P + + + K+G S + V F+D + +G EG+G + ++ Sbjct: 239 FVPRFLPDGQRNAIRLERLKDKLGNRSNASCEVEFQDA---IGWLLGLEGEGIRLILKMG 295 Query: 274 NGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMV 333 R + A S + L H + R FG PL ++ L+ MA +L ++ Sbjct: 296 GMTRFDCALGSHAMMRRAFSLAIYHAHQRHVFGNPLIQQPLMRHVLSRMALQLEGQTALL 355 Query: 334 RNAAVALQEERKDAVALCSMAKLFATDECFAICN-------QALQMHGGYGYLKDYAVQQ 386 A A + R DA A+LF F IC +A+++ GG GY ++ + + Sbjct: 356 FRLARAW-DRRADAKE-ALWARLFTPAAKFVICKRGMPFVAEAMEVLGGIGYCEESELPR 413 Query: 387 YVRDSRVHQILEGSNEVMRILISRSL 412 R+ V+ I EGS +M + + R L Sbjct: 414 LYREMPVNSIWEGSGNIMCLDVLRVL 439 >4Y9J-A nrPDB Length = 593 Score = 74.3 bits (181), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 73/273 (26%), Positives = 124/273 (45%), Gaps = 26/273 (9%) Query: 160 LTEPGSGSDAASLLTSAKKQ--GDHYILNGSKAFISGAGESDIYVVMCR------TGGPG 211 +TE GSD A + Q D Y L+G K F S A ++D+ + + R G Sbjct: 190 MTEKKGGSDVAGGCDTYAVQIDKDTYRLHGYKWF-SSAVDADVALTLARIVDSDGNALEG 248 Query: 212 PKGISCIVV----EKGT-PGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGF 266 +G+S ++ E G G+ + + K+G PT ++ + +A RIG +G+G Sbjct: 249 SRGLSLFLLKIRDESGNLNGIQMVRLKNKLGTKQLPTAELLLDGA---IAERIGDQGRGV 305 Query: 267 LIAVRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRL 326 LN RI+ A SLG + L RD+ R FG+ + TLA M Sbjct: 306 AGISNMLNITRIHNAVASLGYMRRIISLARDYSTKRVVFGQTQSKWPLHTTTLAKMEVDT 365 Query: 327 VAARLMVRNAA--VALQEERKDAVA-------LCSMAKLFATDECFAICNQALQMHGGYG 377 + L++ AA + L E K + + + KL+A + + ++ ++ GG G Sbjct: 366 RGSMLLLFEAARLLGLSEAGKSSDVEAMMLRLITPVLKLYAGKQAVPMVSEGIECFGGQG 425 Query: 378 YLKDYAVQQYVRDSRVHQILEGSNEVMRILISR 410 Y++D + +RD++V I EG+ V+ + + R Sbjct: 426 YMEDTGLPTLLRDAQVTPIWEGTTNVLSLDVLR 458 >4XVX-A nrPDB Length = 389 Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 84/354 (23%), Positives = 155/354 (43%), Gaps = 22/354 (6%) Query: 65 AEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGLSRLDTSVIFE-ALATGCTSTTAY- 122 AE + +E FP ++ LG GV+ D + +R D + E A A G ++ Sbjct: 30 AEAEAQERFPRQLIE---HLGVCGVF---DAKWATDARPDVGKLVELAFALGQLASAGIG 83 Query: 123 --ISIHNMCAWMIDSFGNEEQRHKFCPPLCTMEKFASYCL--TEPGSGSDAASLLTSAKK 178 +S+H+ ++ FG + C + A C+ +E GSD + T + Sbjct: 84 VGVSLHDSAIAILRRFGKSDYLRDICDQ--AIRGAAVLCIGASEESGGSDLQIVETEIRS 141 Query: 179 QGDHYILNGSKAFISGAGESDIYVVMCRT--GGPGPKGISCIVVEKGTPGLSFGKKEKKV 236 + + + G K F+S + +D +V+ R+ P + + VV +S +KV Sbjct: 142 RDGGFEVRGVKKFVSLSPIADHIMVVARSVDHDPTSRHGNVAVVAVPAAQVSVQTPYRKV 201 Query: 237 GWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGGRINIASCSLGAAHASVILTR 296 G T AV D VP + G G GL R++IA + ++ +T Sbjct: 202 GAGPLDTAAVCI-DTWVPADALVARAGTGLAAISWGLAHERMSIAGQIAASCQRAIGITL 260 Query: 297 DHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNAAVALQEERKDAVALCSMAKL 356 + R+QFG+ L +Q L+ +AD+ R+ R + A + E + A A+ A Sbjct: 261 ARMMSRRQFGQTLFEHQALRLRMADLQARVDLLRYALHGIAEQGRLELRTAAAVKVTAAR 320 Query: 357 FATDECFAICNQALQMHGGYGYLKD-YAVQQYVRDSRVHQILEGSNEVMRILIS 409 + + ++ + + GG GYL D + ++ RD ++ ++ G++EV+ L++ Sbjct: 321 LGEE----VISECMHIFGGAGYLVDETTLGKWWRDMKLARVGGGTDEVLWELVA 370 >5GJ7-A nrPDB Length = 398 Score = 55.5 bits (132), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 85/374 (22%), Positives = 147/374 (39%), Gaps = 36/374 (9%) Query: 40 GLNEEQKEFQKVAFDFAA--REMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGG 97 L + +E ++ D A E AP E D+ FP + + G+ + + GG Sbjct: 12 ALPADVRERLRITRDLAQAFHERAP---EHDRAGDFPFENIEDLKASGYVRWTVPVEYGG 68 Query: 98 SGLSRLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSFG--NEEQRHKFCPPLCTMEKF 155 GLS + + E LA G ST I H + G +E C + Sbjct: 69 LGLSLEEMLMHQEVLAKGDGSTALAIGWHVGILLHLRETGAFPDELFRMVCESVVKEGAL 128 Query: 156 ASYCLTEPGSGSDA--ASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGGPGPK 213 + C TEP +GS + T+A K Y + G K F S + +++ Sbjct: 129 INSCATEPATGSPSRGGKPETTAVKVPGGYRITGRKTF-STLSPALTWIM---------- 177 Query: 214 GISCIVVEKGTPGLSFGKKEK---KVGWNSQPTRA-----VIFEDCAVPVANRIGSEGQG 265 ++ V ++ G +KE W++ RA ++ +D VP I + G Sbjct: 178 -VTATVADEDVVGQFLVRKEDVEIVETWDTLGMRATGSHDIVLKDVFVPEERVIVIQRPG 236 Query: 266 FLIAVRGLNGG-RINIASCSLGAAHASVILTRDHLNVRK--QFGEPLASNQYLQFTLADM 322 R G ++I +C LG A A+ ++ + P+A +++ L +M Sbjct: 237 VQAERRPDGSGWLLHIPACYLGIALAARDFALEYAATYRPNTLPHPIAEVPHVEQKLGEM 296 Query: 323 ATRLVAARLMVRNAA----VALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGY 378 +L+AAR ++ + A A EER K AT+ + + A+++ GG Sbjct: 297 ELKLLAARTLLYDLARRFDAASPEERVKLQPQFGAVKTLATNAANQVVDLAMRVVGGRSL 356 Query: 379 LKDYAVQQYVRDSR 392 + +++Y RD R Sbjct: 357 SRALPLERYYRDVR 370 >3MXL-A nrPDB Length = 395 Score = 54.3 bits (129), Expect = 9e-08, Method: Compositional matrix adjust. Identities = 88/353 (24%), Positives = 139/353 (39%), Gaps = 39/353 (11%) Query: 65 AEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGLSRL-DTSVIFEALATGCTSTTAYI 123 A+ D+ FPV+ + A+LG G + ++GG GL+RL D + LA ST Sbjct: 32 ADRDRTGTFPVEAFEQFAKLGLMGATVPAELGGLGLTRLYDVATALMRLAEADASTA--- 88 Query: 124 SIHNMCAWMID-SFG---NEEQRHKFCPPLCTMEKFASYCLTEP-----GSGSDAASLLT 174 AW + S G E +H PP+ M + + E G+ DA ++T Sbjct: 89 -----LAWHVQLSRGLTLTYEWQHG-TPPVRAMAERLLRAMAEGEAAVCGALKDAPGVVT 142 Query: 175 SAKKQG-DHYILNGSKAFISGAG-ESDIYVVMCRTGGPGPKGISCIVVEKGTPGLSFGKK 232 G ++L+G K +S A + +V R G ++ VV + PGL+ Sbjct: 143 ELHSDGAGGWLLSGRKVLVSMAPIATHFFVHAQRRDDDGSVFLAVPVVHRDAPGLTVLDN 202 Query: 233 EKKVGWNSQPTRAVIFEDCAVPVANRI--GSEGQGFLIAVRGLNGGRINIASCSLGAAHA 290 +G + T V+F+ C V + G G + G I + G A A Sbjct: 203 WDGLGMRASGTLEVVFDRCPVRADELLERGPVGARRDAVLAGQTVSSITMLGIYAGIAQA 262 Query: 291 SVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMV-------RNAAVAL--- 340 + + R GEP A + L +A + TRL A R V A+V L Sbjct: 263 ARDIAVGFCAGRG--GEPRAGARAL---VAGLDTRLYALRTTVGAALTNADAASVDLSGD 317 Query: 341 -QEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSR 392 E + + AK+ + A+ + L + GG Y + + + RD R Sbjct: 318 PDERGRRMMTPFQYAKMTVNELAPAVVDDCLSLVGGLAYTAGHPLSRLYRDVR 370 >4ZYJ-A nrPDB Length = 425 Score = 53.5 bits (127), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 88/390 (22%), Positives = 143/390 (36%), Gaps = 44/390 (11%) Query: 40 GLNEEQKEFQKVAFDFAAREMAPNMAEW---DQKELFPVDVMRKAAQLGFGGVYIQTDVG 96 GL E + + D R + AE D++ PV + + + G G + D+G Sbjct: 37 GLCEPKTPAGRRLLDLLERYLPALEAESRDNDREATLPVHLFDRMRKEGVLGATVPEDLG 96 Query: 97 GSGLSRLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSFGNEEQRHKFCPPLCTMEKFA 156 G G+ L + A G + A + F E RH P + A Sbjct: 97 GLGVHSLHDVALALARIAGRDAGVALALHMQFSRGLTLDF---EWRHG-AP---STRPLA 149 Query: 157 SYCLTEPGSG--------SDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTG 208 L + G+G D + Y LNG K +S AG + YVV R Sbjct: 150 EDLLRQMGAGEAVICGAVKDVRGTTVLTRATDGSYRLNGRKTLVSMAGIATHYVVSTRLE 209 Query: 209 GPG-PKGISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFL 267 G P ++ VV + TPGL+ +G S + ++F+ C V +R+ G+ + Sbjct: 210 EAGAPVRLAAPVVARTTPGLTVLDNWDGMGMRSSGSVDIVFDGCPVD-RDRVLPRGEPGV 268 Query: 268 ---IAVRGLNGGRINIASCSLGAAHAS--VILTRDHLNVRKQFGEPLASNQYLQFTLADM 322 A+ G I + +G A A+ + LT +R++ G P ++ T+A++ Sbjct: 269 RDDAALAGQTVSSIAMLGIYVGIAEAARRIALT----ELRRRGGAPAG----VRTTVAEI 320 Query: 323 ATRLVAARLMVRNAAVALQEERKD-----------AVALCSMAKLFATDECFAICNQALQ 371 RL A V +A D + AKL + + L Sbjct: 321 DARLFALHTAVASALTTADRLADDLSGDLAARGRAMMTPFQYAKLLVNRHSVGVVDDCLM 380 Query: 372 MHGGYGYLKDYAVQQYVRDSRVHQILEGSN 401 + GG GY + + + RD R + N Sbjct: 381 LVGGAGYSNSHPLARLYRDVRAGGFMHPYN 410 >3M9V-A nrPDB Length = 439 Score = 52.4 bits (124), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 80/391 (20%), Positives = 150/391 (38%), Gaps = 34/391 (8%) Query: 32 TSCIDPSMGLNEEQKEFQKVAFDFAAREMA---PNMAEWDQKELFPVDVMRKAAQLGFGG 88 T+ D + GL +V D A + AE D+ FP D + G G Sbjct: 7 TARQDSTTGLYAPVTPAGRVLLDRLAAHLPRIRSTAAEHDRDGTFPTDTFDALRKDGLMG 66 Query: 89 VYIQTDVGGSGLSRLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSFGNE----EQRHK 144 + ++GG G+ RL + ++TA +++H + + + G E ++R + Sbjct: 67 ATVPAELGGLGVDRLYDVAVALLAVARADASTA-LALHMQLSRGL-TLGYEWRHGDERAR 124 Query: 145 FCPPLCTMEKFASYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVM 204 A + G ++ T ++L+G K +S A +V+ Sbjct: 125 TLAERILRGMVAGDAVVCSGIKDHHTAVTTLRPDGAGGWLLSGRKTLVSMAPVGTHFVIN 184 Query: 205 CRTGGP-GPKGISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVP-----VANR 258 RT G GP ++ VV + TPG + +G + T ++F+DC +P + + Sbjct: 185 ARTDGTDGPPRLASPVVTRDTPGFTVLDNWDGLGMRASGTVDIVFDDCPIPADHVLMRDP 244 Query: 259 IGSEGQGFLIAVRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFT 318 +G+ L G +++ +G A A+ L R + P A+ L Sbjct: 245 VGARNDAVLA---GQTVSSVSVLGVYVGVAQAAYDTAVAALERRPE--PPQAAALTL--- 296 Query: 319 LADMATRLVAARLMVRNAAVA-----------LQEERKDAVALCSMAKLFATDECFAICN 367 +A++ +RL A R +A A + E + + AKL I + Sbjct: 297 VAEIDSRLYALRATAGSALTAADALSADLSGDMDERGRQMMRHFQCAKLAVNRLAPEIVS 356 Query: 368 QALQMHGGYGYLKDYAVQQYVRDSRVHQILE 398 L + GG Y + + + +RD + + ++ Sbjct: 357 DCLSLVGGASYTAGHPLARLLRDVQAGRFMQ 387 >2C12-A nrPDB Length = 439 Score = 49.3 bits (116), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 81/369 (21%), Positives = 146/369 (39%), Gaps = 51/369 (13%) Query: 79 RKAAQLGFGGVYIQTDVGGSGLSRLDTSVIFE---ALATGCTSTTAYISIHNMCAWMIDS 135 R+A + G + +GG+ S + S+I E A+ + T ++ M + DS Sbjct: 50 REAVRHGLIKAQVPIPLGGTMESLVHESIILEELFAVEPATSITIVATALGLMPVILCDS 109 Query: 136 FGNEEQRHKFCPPLCTME--KFASYCLTEPGSGSD-----AASLLTSAKKQGDHYILNGS 188 +E KF P + E AS +EP ++ L T+A+K G+ ++++G Sbjct: 110 PSLQE---KFLKPFISGEGEPLASLMHSEPNGTANWLQKGGPGLQTTARKVGNEWVISGE 166 Query: 189 KAFISGAG-----ESDIYVVMCRTGGPGPKG----------ISCIVVEKGTPGLSFGKKE 233 K + S +G +D+ V+CR K I+ ++V + T ++ KK+ Sbjct: 167 KLWPSNSGGWDYKGADLACVVCRVSDDPSKPQDPNVDPATQIAVLLVTRET--IANNKKD 224 Query: 234 --------KKVGWNSQPTRAVIFEDCAVPVANRI---GSEGQGFLIAVRGLNG---GRIN 279 + G + F + VP N + G + QG + ++ G + Sbjct: 225 AYQILGEPELAGHITTSGPHTRFTEFHVPHENLLCTPGLKAQGLVETAFAMSAALVGAMA 284 Query: 280 IASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNAAVA 339 I + A V D K E +Q + L D RL +RL+V A Sbjct: 285 IGTARAAFEEALVFAKSDTRGGSKHIIE----HQSVADKLIDCKIRLETSRLLVWKAVTT 340 Query: 340 LQEERKDAVALCSMA---KLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQI 396 L++E + MA K++ TD A++ G Y KD + + + + + + Sbjct: 341 LEDEALEWKVKLEMAMQTKIYTTDVAVECVIDAMKAVGMKSYAKDMSFPRLLNEVMCYPL 400 Query: 397 LEGSNEVMR 405 +G N +R Sbjct: 401 FDGGNIGLR 409 >5YS9-A nrPDB Length = 708 Score = 49.3 bits (116), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 72/315 (22%), Positives = 120/315 (38%), Gaps = 55/315 (17%) Query: 155 FASYCLTEPGSGSDAASLLTSAK--KQGDHYILN-----GSKAFISGAGESDIYVV-MCR 206 + + +TE G GS+ A L T+A + D +I+N +K +I GA S + R Sbjct: 157 YGCFAMTELGHGSNVAGLETTATYIQDTDEFIINTPNTGATKWWIGGAAHSATHTACFAR 216 Query: 207 TGGPGPK-GISCIVVE-------KGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANR 258 G G+ VV+ PG++ G KK+G ++ + F + +P N Sbjct: 217 LLVDGKDYGVKIFVVQLRDVSSHSLMPGIALGDIGKKMGRDAIDNGWIQFTNVRIPRQNM 276 Query: 259 I---------GSEGQGFL--IAVRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFG- 306 + G Q L + L GGR+ + + S + + + + VR+QFG Sbjct: 277 LMKYAKVSSTGKVSQPPLAQLTYGALIGGRVTMIADSFFVSQRFITIALRYACVRRQFGT 336 Query: 307 ---EP---LASNQYLQFTLADMATRLVAARLMVRNAAVALQE------------------ 342 +P + Y Q L + A ++ + + + Sbjct: 337 TPGQPETKIIDYPYHQRRLLPLLAFTYAMKMAADQSQIQYDQTTDLLQTIDPKDKGALGK 396 Query: 343 ---ERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQILEG 399 + K+ A + K F T C I +Q Q GG+GY Q D V EG Sbjct: 397 AIVDLKELFASSAGLKAFTTWTCANIIDQCRQACGGHGYSGYNGFGQAYADWVVQCTWEG 456 Query: 400 SNEVMRILISRSLLQ 414 N V+ + + R L+Q Sbjct: 457 DNNVLCLSMGRGLIQ 471 >3MKH-A nrPDB Length = 438 Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 68/304 (22%), Positives = 113/304 (37%), Gaps = 33/304 (10%) Query: 141 QRHKFCPPLCTME--KFASYCLTEPGSGSDA-----ASLLTSAKKQGDHYILNGSKAFIS 193 Q +F P + E AS +EPG ++A T+A+ +GD +++NG K + + Sbjct: 113 QHAEFLAPFLSGEGSPLASLVFSEPGGVANALEKGAPGFQTTARLEGDEWVINGEKMWAT 172 Query: 194 G-AGES----DIYVVMCRTG------GPGPKGISCIVV-------EKGTPGLSFGKKEKK 235 AG D+ V+CR G P+ I++ G + Sbjct: 173 NCAGWDFKGCDLACVVCRDATTPLEEGQDPENKVMIILVTRADLDRNGEGSFEVLRHVAT 232 Query: 236 VGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGGRINIASCSLGAAHASVILT 295 G S V + + VP N + GQG +A +G + + + +G A+ Sbjct: 233 PGHTSVSGPHVRYTNVRVPTKNVLCPAGQGAKVAFGAFDGSAVLVGAMGVGLMRAAFDAA 292 Query: 296 RDHLNVRKQFGE-PLASNQYLQFTLADMATRLVAARLMVRNAAVALQEERKDAVA---LC 351 + G PL Q L+ + + AAR + AA A++ D A L Sbjct: 293 LKFAKEDNRGGAVPLLERQAFADLLSGVKIQTEAARALTWKAAHAMENGPGDYDARRELA 352 Query: 352 SMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQILEGSNEVMRILISRS 411 AK+F ++ C + G Y + + V I +G N + I R Sbjct: 353 LAAKVFCSEAAVKACTDVINAVGISAYDLQRPFSDLLNTAVVLPIFDGGN----VGIRRR 408 Query: 412 LLQE 415 LQ+ Sbjct: 409 HLQQ 412 >4X28-D nrPDB Length = 373 Score = 45.4 bits (106), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 71/333 (21%), Positives = 125/333 (37%), Gaps = 32/333 (9%) Query: 69 QKEL------FPVDVMRKAAQLGFGGVYIQTDVGGSGLSRLDTSVIFEALATGCTSTTAY 122 Q+EL F ++ RK G +GG G L+ + AL + Y Sbjct: 29 QRELDKLEQRFDRELWRKLIDAGILSSAAPESLGGDGFGVLEQVAVLVALGHQLAAVP-Y 87 Query: 123 ISIHNMCAWMIDSFGNEEQRHKFCPPLCTMEKFASYCLT-EPGSGSDAASLLTSAKKQGD 181 + + A + FG+ E + + + ++ + L E G G A G Sbjct: 88 LESVVLAAGALARFGSPELQQGWGVSAVSGDRILTVALDGEMGEGP------VQAAGTGH 141 Query: 182 HYILNGSKAFISGAGESDIYVVMCRTGGPGPKGISCIVVEKGTPGLSFGKKEKKVGWNSQ 241 Y L G++ + +D ++V T G + +V G PG++ G S Sbjct: 142 GYRLTGTRTQVGYGPVADAFLVPAET----DSGAAVFLVAAGDPGVAV-TALATTGLGS- 195 Query: 242 PTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGGRINIASCSLGAAHASVILTRDHLNV 301 + V A R+G G +AV ++ + LG + +T ++ Sbjct: 196 -VGHLELNGAKVDAARRVG----GTDVAVWLGTLSTLSRTAFQLGVLERGLQMTAEYART 250 Query: 302 RKQFGEPLASNQYLQFTLADMATRLVAARLMVRNAAVALQEER-------KDAVALCSMA 354 R+QF P+ S Q + LAD + RL + AA + E+ + A + A Sbjct: 251 REQFDRPIGSFQAVGQRLADGYIDVKGLRLTLTQAAWRVAEDSLASRECPQPADIDVATA 310 Query: 355 KLFATDECFAICNQALQMHGGYGYLKDYAVQQY 387 +A + + + + +HGG G D+ V +Y Sbjct: 311 GFWAAEAGHRVAHTIVHVHGGVGVDTDHPVHRY 343 >4JEK-A nrPDB Length = 453 Score = 44.7 bits (104), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 70/337 (20%), Positives = 124/337 (36%), Gaps = 27/337 (8%) Query: 85 GFGGVYIQTDVGGSGLSRLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSFGNEEQRHK 144 G + + + GG G + +A S H A MI+ G++EQ Sbjct: 92 GLLSLLVPREYGGWGADWPTAIEVVREIAAADGSLGHLFGYHLTNAPMIELIGSQEQEEH 151 Query: 145 FCPPLCTMEKFASYCLTEPGSGSDAASLLTSAKKQGDH-YILNGSKAFISGAGESDIYVV 203 + + +E + S SA D Y+LNG+K F SGA SD+ V Sbjct: 152 LYTQIAQNNWWTGNASSE--NNSHVLDWKVSATPTEDGGYVLNGTKHFCSGAKGSDLLFV 209 Query: 204 --MCRTGGPGPKGISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGS 261 + + P I + G++ +G + + F + V +G+ Sbjct: 210 FGVVQDDSPQQGAIIAAAIPTSRAGVTPNDDWAAIGMRQTDSGSTDFHNVKVEPDEVLGA 269 Query: 262 EGQGFLIAVRGLNG------GRINIASCSLGAAHASVILTRDHLN----------VRKQF 305 L ++ G ++ A+ LG AH ++ R++ +++ Sbjct: 270 PNAFVLAFIQSERGSLFAPIAQLIFANVYLGIAHGALDAAREYTRTQARPWTPAGIQQAT 329 Query: 306 GEPLASNQYLQFTLA---DMATRLVAARLM--VRNAAVALQ-EERKDAVALCSMAKLFAT 359 +P Y +FT+A A AA L+ V + AL E+R + + S K AT Sbjct: 330 EDPYTIRSYGEFTIALQGADAAAREAAHLLQTVWDKGDALTPEDRGELMVKVSGVKALAT 389 Query: 360 DECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQI 396 + I + ++ G G Y ++ R+ R H + Sbjct: 390 NAALNISSGVFEVIGARGTHPRYGFDRFWRNVRTHSL 426 >1W07-A nrPDB Length = 659 Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 83/360 (23%), Positives = 139/360 (38%), Gaps = 82/360 (22%) Query: 121 AYISIH-NMCAWMIDSFGNEEQRHKFCPPLCTMEKFASYCLTEPGSGSDAASLLTSA--K 177 AY+ +H M I G EEQ+ K+ M+ Y TE G GS+ L T+A Sbjct: 97 AYVDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATLD 156 Query: 178 KQGDHYILN-----GSKAFISGAGESDIY-VVMCRTGGPGPK-GISCIVVE-------KG 223 + D ++++ SK + G G+ + VV R G GI +V+ Sbjct: 157 PKTDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSP 216 Query: 224 TPGLSFGKKEKKVG---WNSQPTRAVIFEDCAVP------VANRIGSEGQ---------- 264 P ++ G K+G +NS ++F+ +P +++ EG+ Sbjct: 217 LPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQL 276 Query: 265 --GFLIAVRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGE--------------- 307 G ++ VR + +A S + A I TR + VR+QFG Sbjct: 277 VYGTMVYVR-----QTIVADASNALSRAVCIATR-YSAVRRQFGAHNGGIETQVIDYKTQ 330 Query: 308 -----PLASNQY--------LQFTLADMATRLVAARLMVRNAAVALQEERKDAVALCSMA 354 PL ++ Y L++ D+ RL A+ A A K +L + A Sbjct: 331 QNRLFPLLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLK---SLTTTA 387 Query: 355 KLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQILEGSNEVMRILISRSLLQ 414 +EC +C GG+GYL + + EG N V+++ ++R L++ Sbjct: 388 TADGIEECRKLC-------GGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFLMK 440 >5Y9D-A nrPDB Length = 709 Score = 38.1 bits (87), Expect = 0.007, Method: Compositional matrix adjust. Identities = 79/358 (22%), Positives = 133/358 (37%), Gaps = 61/358 (17%) Query: 118 STTAYISIHN-MCAWMIDSFGNEEQRHKFCPP--LCTMEKFASYCLTEPGSGSDAASLLT 174 ST +SIHN + I G EQ + + + + + +TE G GS+ L T Sbjct: 123 STRTRLSIHNNLFIGSIRGSGTPEQFKYWVKKGAVAVKQFYGCFAMTELGHGSNLKGLET 182 Query: 175 SA--KKQGDHYILN-----GSKAFISGAGESDIY-------VVMCRTGGPGPKGISCIVV 220 +A + D +I+N +K +I GA + + +V + G + V Sbjct: 183 TATYDQDSDQFIINTPHIGATKWWIGGAAHTSTHCVCFAKLIVHGKDYGTRNFVVPLRNV 242 Query: 221 EKGT--PGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVAN------RIGSEGQGFLIAVRG 272 + G+S G KK+G + + F + +P N ++ G A+ Sbjct: 243 HDHSLKVGVSIGDIGKKMGRDGVDNGWIQFTNVRIPRQNMLMRYAKVSDTGVVTKPALDQ 302 Query: 273 LN-----GGRINIASCSLGAAHASVILTRDHLNVRKQFGE-------------------- 307 L GR+++ + S + + + + VR+QFG Sbjct: 303 LTYGALIRGRVSMIADSFHVSKRFLTIALRYACVRRQFGTSGDTKETKIIDYPYHQRRLL 362 Query: 308 PLASNQYLQFTLADMATRL---VAARLMVRNAAVALQE--------ERKDAVALCSMAKL 356 PL + Y AD A + R++ N Q+ + K+ A + K Sbjct: 363 PLLAYCYAMKMGADEAQKTWIETTDRILALNPNDPAQKNDLEKAVTDTKELFAASAGMKA 422 Query: 357 FATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQILEGSNEVMRILISRSLLQ 414 F T C I ++ Q GG+GY Q D V EG N V+ + + R L+Q Sbjct: 423 FTTWGCAKIIDECRQACGGHGYSGYNGFGQGYADWVVQCTWEGDNNVLCLSMGRGLVQ 480 >5XDD-A nrPDB Length = 414 Score = 35.4 bits (80), Expect = 0.046, Method: Compositional matrix adjust. Identities = 73/353 (20%), Positives = 130/353 (36%), Gaps = 44/353 (12%) Query: 76 DVMRKAAQLGFGGVYIQTDVGGSGLSRLDTSVIFEALATGCTSTTAYISIHNMCAWMIDS 135 D +R++ G + I + GG G S +A+ S H +D Sbjct: 47 DAIRRS---GLLTLLISKERGGLGESWPTVYEAIAEIASADASLGHLFGYHFSNFAYVDL 103 Query: 136 FGNEEQRHKFCPPLCTMEKFASYCLTEPGSGSDAASL---LTSAKKQGDHYILNGSKAFI 192 F + EQ+ ++ P F L S ++A L +T+ Y +NG+KAF Sbjct: 104 FASPEQKARWYPQAVRERWF----LGNASSENNAHVLDWRVTATPLPDGSYEINGTKAFC 159 Query: 193 SGAGESDIYVVMCRTG-GPGPKG-ISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFED 250 SG+ ++D +V T P G I ++ G+ +G + +V F Sbjct: 160 SGSADADRLLVFAVTSRDPNGDGRIVAALIPSDRAGVQVNGDWDSLGMRQTDSGSVTFSG 219 Query: 251 CAVPVANRIGSEGQGFLIAVRGLNGGRINIAS-------------CSLGAAHASVILTRD 297 V +G+ GQ + +G + ++ + + GA + +R Sbjct: 220 VVVYPDELLGTPGQ---VTDAFASGSKPSLWTPITQLIFTHLYLGIARGALEEAAHYSRS 276 Query: 298 H------LNVRKQFGEPLASNQYLQFT----LADMATRLVAAR---LMVRNAAVALQEER 344 H V K +P Y +F +A+ R VA R L RN E+R Sbjct: 277 HSRPFTLAGVEKATEDPYVLAIYGEFAAQLQVAEAGAREVALRVQELWERNHVTP--EQR 334 Query: 345 KDAVALCSMAKLFATDECFAICNQALQMHGGYGYL-KDYAVQQYVRDSRVHQI 396 + + AK+ AT + ++ + G + + ++ RD+R H + Sbjct: 335 GQLMVQVASAKIVATRLVIELTSRLYEAMGARAAASRQFGFDRFWRDARTHTL 387 >1IS2-A nrPDB Length = 661 Score = 35.0 bits (79), Expect = 0.063, Method: Compositional matrix adjust. Identities = 69/330 (20%), Positives = 118/330 (35%), Gaps = 65/330 (19%) Query: 140 EQRHKFCPPLCTMEKFASYCLTEPGSGSDAASLLTSA--KKQGDHYILNGS-----KAFI 192 EQ+ +F P +E +Y TE G G+ L T+A + +ILN K + Sbjct: 118 EQQERFFMPAWNLEITGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWP 177 Query: 193 SGAGE-SDIYVVMCRTGGPGP-KGISCIVV-------EKGTPGLSFGKKEKKVGWNSQPT 243 G G+ S+ +V+ + G G+ VV K PG++ G K G+ Sbjct: 178 GGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDN 237 Query: 244 RAVIFEDCAVPVANRIGSEGQ-----------------GFLIAVRGL---NGGRINIASC 283 + ++ +P N + Q G ++ VR N + +C Sbjct: 238 GYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSKAC 297 Query: 284 SLGAAHASVILTRDHLNVRKQFGEP----LASNQYLQFTLADMATRLVAARLMVRNAAVA 339 ++ +++V R +++ EP + QY F L A ++ + Sbjct: 298 TIAIRYSAV---RRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLR 354 Query: 340 LQE--------ERKDAVALCSMAKLFAT-------DECFAICNQALQMHGGYGYLKDYAV 384 + E E + AL + K F T +EC C GG+GY + Sbjct: 355 INESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMAC-------GGHGYSHSSGI 407 Query: 385 QQYVRDSRVHQILEGSNEVMRILISRSLLQ 414 EG N VM + +R L++ Sbjct: 408 PNIYVTFTPACTFEGENTVMMLQTARFLMK 437 >3DFG-A nrPDB Length = 162 Score = 29.6 bits (65), Expect = 2.5, Method: Compositional matrix adjust. Identities = 15/48 (31%), Positives = 25/48 (52%), Gaps = 3/48 (6%) Query: 67 WDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGLSRLDTSVIFEALAT 114 W F V+R A G+G ++I+ ++G G LD+ + A+AT Sbjct: 63 WQDDVRFAASVVRNRASSGYGPLHIRAELGTHG---LDSDAVSAAMAT 107 >6A7I-A nrPDB Length = 411 Score = 29.3 bits (64), Expect = 3.1, Method: Compositional matrix adjust. Identities = 27/110 (24%), Positives = 48/110 (43%), Gaps = 6/110 (5%) Query: 165 SGSDAASLLTSAKKQGDHY----ILNGSKAFISGAGESDIYVVMCRTGGPGPKGISCIVV 220 G D S L +A + GDH I+N + I+ E+ I +++ V Sbjct: 207 PGDDLTSALIAASENGDHLTDEEIVNTLQLIIAAGHETTISLIVNVVEALQTHPEQRKKV 266 Query: 221 EKGTPGLSFGKKEKKVGWNSQPTRAVI-FEDCAVPVANRIGSEGQGFLIA 269 G G G E+ + WN+ + +I F + V ++I +G+G +I+ Sbjct: 267 LNGEIGWD-GVIEETLRWNTPTSHVLIRFATEDIEVGDKILPKGEGLIIS 315 >4J3X-A nrPDB Length = 905 Score = 28.9 bits (63), Expect = 4.2, Method: Compositional matrix adjust. Identities = 13/39 (33%), Positives = 23/39 (58%), Gaps = 3/39 (7%) Query: 271 RGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPL 309 RG+NG ++N++ +G+ + + RD +N FG PL Sbjct: 542 RGINGSQLNMSGTGIGSFNDRI---RDAINGGNPFGNPL 577 >5A31-O nrPDB Length = 755 Score = 28.5 bits (62), Expect = 6.4, Method: Compositional matrix adjust. Identities = 15/37 (40%), Positives = 20/37 (54%) Query: 335 NAAVALQEERKDAVALCSMAKLFATDECFAICNQALQ 371 NA V AVALC +A+L A CFA ++ L+ Sbjct: 455 NAGVQQNNTESFAVALCHLAELHAEQGCFAAASEVLK 491 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1RX0-A nrPDB 521 e-148 1JQI-A nrPDB 486 e-138 4L1F-A nrPDB 480 e-136 5OL2-C nrPDB 479 e-135 5LNX-A nrPDB 476 e-135 2VIG-A nrPDB 473 e-134 2A1T-A nrPDB 464 e-131 4N5F-A nrPDB 462 e-130 1UKW-A nrPDB 460 e-130 1IVH-A nrPDB 458 e-129 4U83-A nrPDB 457 e-129 6FAH-C nrPDB 456 e-129 3MDE-A nrPDB 445 e-125 4O5M-A nrPDB 445 e-125 4M9A-A nrPDB 443 e-125 1BUC-A nrPDB 443 e-125 3PFD-A nrPDB 439 e-123 2JIF-A nrPDB 430 e-121 4IRN-A nrPDB 429 e-121 4KTO-A nrPDB 426 e-119 2PG0-A nrPDB 423 e-119 4IV6-A nrPDB 415 e-116 2DVL-A nrPDB 412 e-115 3MPI-A nrPDB 403 e-112 3GNC-A nrPDB 402 e-112 3NF4-A nrPDB 400 e-112 2Z1Q-A nrPDB 399 e-111 3OWA-A nrPDB 392 e-109 2EBA-A nrPDB 389 e-108 3R7K-A nrPDB 389 e-108 2CX9-A nrPDB 383 e-107 3SF6-A nrPDB 382 e-106 3B96-A nrPDB 379 e-105 4W9U-A nrPDB 378 e-105 1SIR-A nrPDB 374 e-104 3SWO-A nrPDB 373 e-104 5ZW7-A nrPDB 368 e-102 3P4T-A nrPDB 368 e-102 6ES9-A nrPDB 365 e-101 2IX5-A nrPDB 363 e-101 6CY8-B nrPDB 361 e-100 5AHS-A nrPDB 344 5e-95 5IDU-A nrPDB 339 9e-94 5JSC-A nrPDB 318 4e-87 4RM7-A nrPDB 299 2e-81 2WBI-A nrPDB 290 7e-79 4HR3-A nrPDB 285 3e-77 1R2J-A nrPDB 276 1e-74 4X28-A nrPDB 270 8e-73 5GJ7-A nrPDB 256 2e-68 4ZYJ-A nrPDB 244 5e-65 4JEK-A nrPDB 244 5e-65 2C12-A nrPDB 240 5e-64 3M9V-A nrPDB 240 6e-64 3MXL-A nrPDB 229 2e-60 3MKH-A nrPDB 227 7e-60 5YS9-A nrPDB 217 9e-57 4X28-D nrPDB 217 1e-56 3U33-A nrPDB 216 1e-56 5EZ3-A nrPDB 215 4e-56 4XVX-A nrPDB 205 2e-53 4Y9J-A nrPDB 203 9e-53 1W07-A nrPDB 190 1e-48 Sequences not found previously or not previously below threshold: 5Y9D-A nrPDB 202 3e-52 2FON-A nrPDB 183 2e-46 5XDD-A nrPDB 179 2e-45 1IS2-A nrPDB 155 4e-38 5K3G-A nrPDB 141 4e-34 5K3J-A nrPDB 131 6e-31 2JBS-A nrPDB 107 1e-23 5LVW-A nrPDB 102 3e-22 2RFQ-A nrPDB 101 8e-22 3AFF-A nrPDB 95 5e-20 2OR0-A nrPDB 73 3e-13 3WG8-A nrPDB 45 6e-05 3HWC-A nrPDB 45 7e-05 6MSO-A nrPDB 42 5e-04 4M03-A nrPDB 42 6e-04 3PSP-A nrPDB 41 0.001 5CHZ-A nrPDB 41 0.001 1U8V-A nrPDB 40 0.003 2YYI-A nrPDB 40 0.003 4XBS-A nrPDB 38 0.007 4OTK-A nrPDB 38 0.008 4NRS-A nrPDB 38 0.009 5JYK-A nrPDB 38 0.010 5ILA-A nrPDB 38 0.010 3ZF4-A nrPDB 38 0.011 3LNB-A nrPDB 37 0.013 6MSN-A nrPDB 37 0.014 5GVX-A nrPDB 37 0.014 5Z6H-A nrPDB 37 0.014 3LBE-A nrPDB 37 0.014 6CF1-A nrPDB 37 0.017 5K53-A nrPDB 37 0.017 5C1S-A nrPDB 37 0.018 5U50-A nrPDB 37 0.019 3VT2-A nrPDB 36 0.021 4H27-A nrPDB 36 0.022 3OXG-A nrPDB 36 0.024 4KML-A nrPDB 36 0.025 5J7Z-A nrPDB 36 0.025 5HXY-A nrPDB 36 0.026 5HK8-A nrPDB 36 0.026 3PLN-A nrPDB 36 0.026 3NC3-A nrPDB 36 0.026 2UXN-B nrPDB 36 0.026 5Z9R-A nrPDB 36 0.026 5A2B-A nrPDB 36 0.027 5GV1-A nrPDB 36 0.029 3L8A-A nrPDB 36 0.029 4ZCK-A nrPDB 36 0.030 3DEZ-A nrPDB 36 0.031 5CTQ-A nrPDB 36 0.032 4ABN-A nrPDB 36 0.034 4Y12-A nrPDB 36 0.036 3OIX-A nrPDB 36 0.036 5EX6-C nrPDB 36 0.038 5ZBB-B nrPDB 36 0.039 4U5I-A nrPDB 36 0.041 4N8K-A nrPDB 36 0.043 4E1Q-A nrPDB 35 0.047 4J0Q-A nrPDB 35 0.049 3QAU-A nrPDB 35 0.051 5K52-A nrPDB 35 0.053 4WTS-A nrPDB 35 0.054 3RPL-B nrPDB 35 0.057 5JRE-A nrPDB 35 0.059 4MSX-A nrPDB 35 0.065 5J32-A nrPDB 35 0.070 4X9L-A nrPDB 35 0.071 3QLL-A nrPDB 35 0.071 4M02-A nrPDB 35 0.075 3K3P-A nrPDB 35 0.075 3L87-A nrPDB 35 0.085 5JZV-A nrPDB 35 0.086 6O09-C nrPDB 35 0.092 5XTP-A nrPDB 35 0.092 4M46-A nrPDB 35 0.092 4M00-A nrPDB 35 0.092 4IG7-A nrPDB 35 0.092 4HG5-A nrPDB 35 0.092 4HBK-A nrPDB 35 0.092 3LEH-A nrPDB 35 0.092 3L9D-A nrPDB 35 0.092 3L9C-A nrPDB 35 0.092 3L7R-A nrPDB 35 0.092 6GII-A nrPDB 35 0.098 5C2O-A nrPDB 35 0.098 3SR7-A nrPDB 35 0.098 4XCH-A nrPDB 34 0.10 4B28-A nrPDB 34 0.10 3L86-A nrPDB 34 0.11 4NZZ-A nrPDB 34 0.11 3P2M-A nrPDB 34 0.12 3L7V-A nrPDB 34 0.14 3NIB-A nrPDB 34 0.15 6ERD-A nrPDB 34 0.15 4XWN-A nrPDB 34 0.15 3UDT-A nrPDB 34 0.16 2NT8-A nrPDB 34 0.16 4ETN-A nrPDB 33 0.17 5JZX-A nrPDB 33 0.18 4QPJ-C nrPDB 33 0.18 3W53-A nrPDB 33 0.19 4EGS-A nrPDB 33 0.19 5XCN-X nrPDB 33 0.22 3BGK-A nrPDB 33 0.24 3LA8-A nrPDB 33 0.26 3MGC-A nrPDB 33 0.27 5LW6-A nrPDB 33 0.28 2LEC-A nrPDB 33 0.30 3GZ3-A nrPDB 33 0.33 4QPJ-A nrPDB 33 0.34 3QWY-A nrPDB 33 0.36 4LIV-A nrPDB 33 0.37 2WST-A nrPDB 32 0.53 4NV8-A nrPDB 32 0.58 4WZH-A nrPDB 31 0.64 3UL6-A nrPDB 31 0.64 3CNC-A nrPDB 31 0.85 3RK6-A nrPDB 31 1.0 4G32-A nrPDB 31 1.3 2YCJ-A nrPDB 31 1.4 3DR5-A nrPDB 31 1.4 4LGZ-A nrPDB 30 1.9 6DGE-A nrPDB 30 1.9 3VQX-A nrPDB 30 2.0 4GAX-A nrPDB 30 2.1 5M07-A nrPDB 30 2.3 5YBH-A nrPDB 30 2.3 1R20-D nrPDB 30 2.4 4QNW-A nrPDB 29 2.6 6J5G-A nrPDB 29 2.9 4IXL-A nrPDB 29 3.2 5LOW-D nrPDB 29 3.2 4M4V-A nrPDB 29 3.2 1VHE-A nrPDB 29 3.6 2Q3R-A nrPDB 29 3.6 5UIC-A nrPDB 29 4.0 5W8P-A nrPDB 29 4.1 6HX8-E nrPDB 29 4.6 5XAF-E nrPDB 29 4.6 1G29-1 nrPDB 29 4.9 5YRZ-B nrPDB 29 5.2 6B1B-A nrPDB 29 5.4 2J08-A nrPDB 28 5.8 6CHV-A nrPDB 28 5.9 2GG4-A nrPDB 28 6.0 4DBZ-A nrPDB 28 6.1 1ICQ-A nrPDB 28 8.5 5DU2-A nrPDB 28 9.8 >1RX0-A nrPDB Length = 393 Score = 521 bits (1343), Expect = e-148, Method: Composition-based stats. Identities = 392/393 (99%), Positives = 393/393 (100%) Query: 23 LVQTGHRSLTSCIDPSMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAA 82 +VQTGHRSLTSCIDPSMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAA Sbjct: 1 MVQTGHRSLTSCIDPSMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAA 60 Query: 83 QLGFGGVYIQTDVGGSGLSRLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSFGNEEQR 142 QLGFGGVYIQTDVGGSGLSRLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSFGNEEQR Sbjct: 61 QLGFGGVYIQTDVGGSGLSRLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSFGNEEQR 120 Query: 143 HKFCPPLCTMEKFASYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYV 202 HKFCPPLCTMEKFASYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYV Sbjct: 121 HKFCPPLCTMEKFASYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYV 180 Query: 203 VMCRTGGPGPKGISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSE 262 VMCRTGGPGPKGISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSE Sbjct: 181 VMCRTGGPGPKGISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSE 240 Query: 263 GQGFLIAVRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADM 322 GQGFLIAVRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADM Sbjct: 241 GQGFLIAVRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADM 300 Query: 323 ATRLVAARLMVRNAAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDY 382 ATRLVAARLMVRNAAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDY Sbjct: 301 ATRLVAARLMVRNAAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDY 360 Query: 383 AVQQYVRDSRVHQILEGSNEVMRILISRSLLQE 415 AVQQYVRDSRVHQILEGSNEVMRILISRSLLQE Sbjct: 361 AVQQYVRDSRVHQILEGSNEVMRILISRSLLQE 393 >1JQI-A nrPDB Length = 388 Score = 486 bits (1251), Expect = e-138, Method: Composition-based stats. Identities = 144/379 (37%), Positives = 229/379 (60%), Gaps = 3/379 (0%) Query: 38 SMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGG 97 S+ L E + ++ DFA +E+ P A+ D++ LFP ++K +LG + + ++ G Sbjct: 7 SVELPETHQMLRQTCRDFAEKELVPIAAQLDKEHLFPTSQVKKMGELGLLAMDVPEELSG 66 Query: 98 SGLSRLDTSVIFEALATGCTSTTAYISIHN-MCAWMIDSFGNEEQRHKFCPPLCTMEKFA 156 +GL L S+ E ++ GC ST +S++N + I FG+ +Q+ ++ P +K Sbjct: 67 AGLDYLAYSIALEEISRGCASTGVIMSVNNSLYLGPILKFGSSQQKQQWITPFTNGDKIG 126 Query: 157 SYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTG-GPGPKGI 215 + L+EPG+GSDA + T+A+++GD ++LNG+KA+I+ + E+ VV T KGI Sbjct: 127 CFALSEPGNGSDAGAASTTAREEGDSWVLNGTKAWITNSWEASATVVFASTDRSRQNKGI 186 Query: 216 SCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNG 275 S +V TPGL+ GKKE K+G + T +IFEDC +P N +G G GF IA++ L+ Sbjct: 187 SAFLVPMPTPGLTLGKKEDKLGIRASSTANLIFEDCRIPKENLLGEPGMGFKIAMQTLDM 246 Query: 276 GRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRN 335 GRI IAS +LG A AS+ + R FG PL Q +QF LADMA L +ARL+ Sbjct: 247 GRIGIASQALGIAQASLDCAVKYAENRHAFGAPLTKLQNIQFKLADMALALESARLLTWR 306 Query: 336 AAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQ 395 AA+ L++ +K +MAKL A++ AI +QA+Q+ GG GY+ + ++Y RD+R+ + Sbjct: 307 AAM-LKDNKKPFTKESAMAKLAASEAATAISHQAIQILGGMGYVTEMPAERYYRDARITE 365 Query: 396 ILEGSNEVMRILISRSLLQ 414 I EG++E+ R++I+ LL+ Sbjct: 366 IYEGTSEIQRLVIAGHLLR 384 >4L1F-A nrPDB Length = 383 Score = 480 bits (1236), Expect = e-136, Method: Composition-based stats. Identities = 151/380 (39%), Positives = 230/380 (60%), Gaps = 3/380 (0%) Query: 38 SMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGG 97 L E+Q+ + +A +FA + +AP + E D+ ++ ++ K + GF G+ + GG Sbjct: 2 DFNLTEDQQMIKDMAAEFAEKFLAPTVEERDKAHIWDRKLIDKMGEAGFCGICFPEEYGG 61 Query: 98 SGLSRLDTSVIFEALATGCTSTTAYISIH-NMCAWMIDSFGNEEQRHKFCPPLCTMEKFA 156 GL L + E L+ T +S + ++CA I FG EEQ+ K+ P+ Sbjct: 62 MGLDVLSYILAVEELSKVDDGTGITLSANVSLCATPIYMFGTEEQKQKYLAPIAEGTHVG 121 Query: 157 SYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTG-GPGPKGI 215 ++ LTEP +G+DA++ T+A +GD YILNGSK FI+ E+D YVV T G GI Sbjct: 122 AFGLTEPSAGTDASAQQTTAVLKGDKYILNGSKIFITNGKEADTYVVFAMTDKSQGVHGI 181 Query: 216 SCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNG 275 S ++EKG PG FGK E K+G ++ T +IFEDC VP N +G EG+GF IA+ L+G Sbjct: 182 SAFILEKGMPGFRFGKIEDKMGGHTSITAELIFEDCEVPKENLLGKEGEGFKIAMETLDG 241 Query: 276 GRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRN 335 GRI +A+ +LG A ++ + R+QFG ++ Q LQF +ADMAT++ AAR +V + Sbjct: 242 GRIGVAAQALGIAEGALAAAVKYSKEREQFGRSISKFQALQFMMADMATKIEAARYLVYH 301 Query: 336 AAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQ 395 AA+ L+ E K +MAK FA+D + A+Q+ GGYGY DY ++Y+R++++ Q Sbjct: 302 AAM-LKNEGKPYSEAAAMAKCFASDVAMEVTTDAVQIFGGYGYTVDYPAERYMRNAKITQ 360 Query: 396 ILEGSNEVMRILISRSLLQE 415 I EG+N+VMRI+ SR+LL++ Sbjct: 361 IYEGTNQVMRIVTSRALLRD 380 >5OL2-C nrPDB Length = 378 Score = 479 bits (1233), Expect = e-135, Method: Composition-based stats. Identities = 159/371 (42%), Positives = 226/371 (60%), Gaps = 3/371 (0%) Query: 46 KEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGLSRLDT 105 + +++ FA E+ P E D++E FP + + K A+ G G+ + GG G + Sbjct: 9 QMLKELYVSFAENEVKPLATELDEEERFPYETVEKMAKAGMMGIPYPKEYGGEGGDTVGY 68 Query: 106 SVIFEALATGCTSTTAYISIH-NMCAWMIDSFGNEEQRHKFCPPLCTMEKFASYCLTEPG 164 + E L+ C +T +S H ++ +W I +GNEEQ+ KF PL + EK ++ LTEP Sbjct: 69 IMAVEELSRVCGTTGVILSAHTSLGSWPIYQYGNEEQKQKFLRPLASGEKLGAFGLTEPN 128 Query: 165 SGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTG-GPGPKGISCIVVEKG 223 +G+DA+ T+A GD YILNGSK FI+ A DIYVVM T G KGIS +VEKG Sbjct: 129 AGTDASGQQTTAVLDGDEYILNGSKIFITNAIAGDIYVVMAMTDKSKGNKGISAFIVEKG 188 Query: 224 TPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGGRINIASC 283 TPG SFG KEKK+G T +IFEDC +P N +G EGQGF IA+ L+GGRI IA+ Sbjct: 189 TPGFSFGVKEKKMGIRGSATSELIFEDCRIPKENLLGKEGQGFKIAMSTLDGGRIGIAAQ 248 Query: 284 SLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNAAVALQEE 343 +LG A ++ T ++ R QFG PL+ Q QF LADM ++ AAR +V AA+ Sbjct: 249 ALGLAQGALDETVKYVKERVQFGRPLSKFQNTQFQLADMEVKVQAARHLVYQAAINKDLG 308 Query: 344 RKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQILEGSNEV 403 K +MAKLFA + + +A+Q+HGGYGY +DY V++ +RD+++ +I EG++EV Sbjct: 309 -KPYGVEAAMAKLFAAETAMEVTTKAVQLHGGYGYTRDYPVERMMRDAKITEIYEGTSEV 367 Query: 404 MRILISRSLLQ 414 R++IS LL+ Sbjct: 368 QRMVISGKLLK 378 >5LNX-A nrPDB Length = 379 Score = 476 bits (1226), Expect = e-135, Method: Composition-based stats. Identities = 154/377 (40%), Positives = 224/377 (59%), Gaps = 3/377 (0%) Query: 39 MGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGS 98 M + +EQ +K+ DFA +E+AP ++ + FP +++K + G G+ + GG+ Sbjct: 1 MHVTQEQVMMRKMVRDFARKEIAPAAEIMEKTDEFPFQLIKKMGKHGLMGIPVPEQYGGA 60 Query: 99 GLSRLDTSVIFEALATGCTSTTAYISIHNMCA-WMIDSFGNEEQRHKFCPPLCTMEKFAS 157 G + + ++ + +S+H I FGNEEQ+ K+ P L + + + Sbjct: 61 GADVVSYILAIHEISRISAAVGVILSVHTSVGTNPILYFGNEEQKMKYIPNLASGDHLGA 120 Query: 158 YCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTG-GPGPKGIS 216 + LTEP SGSDA SL T+A K+ Y+LNGSK FI+ G +DIY+ T G GIS Sbjct: 121 FALTEPHSGSDAGSLRTTAIKKNGKYLLNGSKIFITNGGAADIYITFALTAPDQGRHGIS 180 Query: 217 CIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGG 276 +VEK TPG + GKKE+K+G T +IF++ VP AN +G EG GF IA+ LN G Sbjct: 181 AFIVEKNTPGFTVGKKERKLGLYGSNTTELIFDNAEVPEANLLGKEGDGFHIAMANLNVG 240 Query: 277 RINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNA 336 RI IA+ +LG A A++ D+ R QFG P+A+NQ + F LADMATR AAR +V +A Sbjct: 241 RIGIAAQALGIAEAALEHAVDYAKQRVQFGRPIAANQGISFKLADMATRAEAARHLVYHA 300 Query: 337 AVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQI 396 A L + SMAK FA+D A+Q++GGYGY+KDY V++ +RD++V QI Sbjct: 301 AD-LHNRGLNCGKEASMAKQFASDAAVKAALDAVQIYGGYGYMKDYPVERLLRDAKVTQI 359 Query: 397 LEGSNEVMRILISRSLL 413 EG+NE+ R++IS+ LL Sbjct: 360 YEGTNEIQRLIISKYLL 376 >2VIG-A nrPDB Length = 391 Score = 473 bits (1217), Expect = e-134, Method: Composition-based stats. Identities = 141/379 (37%), Positives = 227/379 (59%), Gaps = 3/379 (0%) Query: 38 SMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGG 97 S+ L E + + DFA +E+ P A+ D++ LFP ++K LG + + ++GG Sbjct: 3 SVELPETHQMLLQTCRDFAEKELFPIAAQVDKEHLFPAAQVKKMGGLGLLAMDVPEELGG 62 Query: 98 SGLSRLDTSVIFEALATGCTSTTAYISIHN-MCAWMIDSFGNEEQRHKFCPPLCTMEKFA 156 +GL L ++ E ++ GC ST +S++N + I FG++EQ+ + P + +K Sbjct: 63 AGLDYLAYAIAMEEISRGCASTGVIMSVNNSLYLGPILKFGSKEQKQAWVTPFTSGDKIG 122 Query: 157 SYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTG-GPGPKGI 215 + L+EPG+GSDA + T+A+ +GD ++LNG+KA+I+ A E+ VV T K I Sbjct: 123 CFALSEPGNGSDAGAASTTARAEGDSWVLNGTKAWITNAWEASAAVVFASTDRALQNKSI 182 Query: 216 SCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNG 275 S +V TPGL+ GKKE K+G T +IFEDC +P + +G G GF IA++ L+ Sbjct: 183 SAFLVPMPTPGLTLGKKEDKLGIRGSSTANLIFEDCRIPKDSILGEPGMGFKIAMQTLDM 242 Query: 276 GRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRN 335 GRI IAS +LG A ++ ++ R FG PL Q +QF LADMA L +ARL+ Sbjct: 243 GRIGIASQALGIAQTALDCAVNYAENRMAFGAPLTKLQVIQFKLADMALALESARLLTWR 302 Query: 336 AAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQ 395 AA+ L++ +K + +MAKL A++ AI +QA+Q+ GG GY+ + +++ RD+R+ + Sbjct: 303 AAM-LKDNKKPFIKEAAMAKLAASEAATAISHQAIQILGGMGYVTEMPAERHYRDARITE 361 Query: 396 ILEGSNEVMRILISRSLLQ 414 I EG++E+ R++I+ LL+ Sbjct: 362 IYEGTSEIQRLVIAGHLLR 380 >2A1T-A nrPDB Length = 421 Score = 464 bits (1194), Expect = e-131, Method: Composition-based stats. Identities = 131/404 (32%), Positives = 222/404 (54%), Gaps = 9/404 (2%) Query: 20 LRVLVQTGHRSLTSCIDP----SMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPV 75 R ++ H +P S E+QKEFQ A FA E+ P AE+D+ +PV Sbjct: 16 SRFHWRSQHTKANRQREPGLGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPV 75 Query: 76 DVMRKAAQLGFGGVYIQTDVGGSGLSRLDTSVIFEALATGCTSTTAYISIHNMCAWMIDS 135 ++R+A +LG +I + GG GL D +I E LA GCT I +++ I Sbjct: 76 PLIRRAWELGLMNTHIPENCGGLGLGTFDACLISEELAYGCTGVQTAIEGNSLGQMPIII 135 Query: 136 FGNEEQRHKFCPPLCTMEKFASYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGA 195 GN++Q+ K+ + +YC+TEPG+GSD A + T A+K+GD YI+NG K +I+ Sbjct: 136 AGNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNG 195 Query: 196 GESDIYVVMCRTG----GPGPKGISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDC 251 G+++ Y ++ R+ P K + +VE TPG+ G+KE +G TR ++FED Sbjct: 196 GKANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDV 255 Query: 252 AVPVANRIGSEGQGFLIAVRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLAS 311 VP N + +G GF +A+ + R +A+ ++G A ++ + RK FG+ L Sbjct: 256 KVPKENVLIGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVE 315 Query: 312 NQYLQFTLADMATRLVAARLMVRNAAVALQEERKDAVALCSMAKLFATDECFAICNQALQ 371 +Q + F LA+MA ++ AR+ + AA + R++ S+AK FA D + A+Q Sbjct: 316 HQAISFMLAEMAMKVELARMSYQRAAWEVDSGRRNTY-YASIAKAFAGDIANQLATDAVQ 374 Query: 372 MHGGYGYLKDYAVQQYVRDSRVHQILEGSNEVMRILISRSLLQE 415 + GG G+ +Y V++ +RD++++QI EG++++ R++++R + + Sbjct: 375 ILGGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAREHIDK 418 >4N5F-A nrPDB Length = 385 Score = 462 bits (1190), Expect = e-130, Method: Composition-based stats. Identities = 137/373 (36%), Positives = 218/373 (58%), Gaps = 3/373 (0%) Query: 42 NEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGLS 101 E+Q+ + A FA +APN A+WD P ++ + +LG G+ + ++GGS Sbjct: 14 TEDQRMIRDAARAFATEMLAPNAAQWDHDAHLPDAIVAQLGELGLLGMIVPQELGGSYTD 73 Query: 102 RLDTSVIFEALATGCTSTTAYISIHNMCA-WMIDSFGNEEQRHKFCPPLCTMEKFASYCL 160 + ++ E +A G + +S+HN I FG Q+ ++ + ++CL Sbjct: 74 YVAYALAMEEVAAGDAACATMMSVHNSVGCGPILGFGTPAQKDRWLADMAAGRVIGAFCL 133 Query: 161 TEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGGP-GPKGISCIV 219 TEP +GS+A +L T A+ + ++LNG+K F++ + + +V T G +GIS + Sbjct: 134 TEPHAGSEANNLRTRAELRDGQWVLNGAKQFVTNGQRAGVAIVFAMTDPEAGKRGISAFL 193 Query: 220 VEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGGRIN 279 V TPG GK EKK+G + T + FE+CA+P N +G+ G+G IA+ L GGRI Sbjct: 194 VPTDTPGFIVGKPEKKMGIRASDTCPITFENCAIPEDNLLGNRGEGLKIALSNLEGGRIG 253 Query: 280 IASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNAAVA 339 IA+ +LG A A+ R + R QFG+P+A +Q +Q LADMA ++ AARL+V +AA Sbjct: 254 IAAQALGIARAAFDKARRYAGERVQFGKPIAEHQAIQQKLADMAVQINAARLLVHHAA-K 312 Query: 340 LQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQILEG 399 L+ ++ S AKLFA++ +C+ A+Q+HGGYGYL DY V+++ RD+R+ QI EG Sbjct: 313 LRTAGLPCLSEASQAKLFASEMAERVCSDAIQIHGGYGYLVDYEVERHYRDARITQIYEG 372 Query: 400 SNEVMRILISRSL 412 ++EV R++I+R L Sbjct: 373 TSEVQRMVIARQL 385 >1UKW-A nrPDB Length = 379 Score = 460 bits (1183), Expect = e-130, Method: Composition-based stats. Identities = 145/377 (38%), Positives = 220/377 (58%), Gaps = 2/377 (0%) Query: 38 SMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGG 97 L EEQ++ Q +A FA + P E+D+KE P V+ K ++G I + GG Sbjct: 2 DFSLTEEQRQLQALARRFAKEVILPVAQEYDEKEEVPWPVIEKLHEVGLLNAIIPEEYGG 61 Query: 98 SGLSRLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSFGNEEQRHKFCPPLCTMEKFAS 157 GL LD ++ E LA C ++ + G EEQ+ +F PL A+ Sbjct: 62 MGLKMLDEVIVGEELAYACMGIYTIPMASDLGITPVLLAGTEEQKERFLRPLTEKPALAA 121 Query: 158 YCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGGP-GPKGIS 216 + L+EPG+GSDAA+L T A +QGDHY+LNG+K +IS GE++ VV KG+ Sbjct: 122 FALSEPGNGSDAAALKTRAIRQGDHYVLNGTKMWISNGGEAEWVVVFATVNPELRHKGVV 181 Query: 217 CIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGG 276 +VVE+GTPG K K+G + T ++FED VPV NR+G EG+GF IA++ LN Sbjct: 182 ALVVERGTPGFKAIKIHGKMGQRASGTYELVFEDVKVPVENRLGEEGEGFKIAMQTLNKT 241 Query: 277 RINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNA 336 RI +A+ S+G A ++ R + R+ FGEP+A+ Q +QF L DM + AR+ A Sbjct: 242 RIPVAAGSVGVARRALDEARKYAKEREAFGEPIANFQAIQFKLVDMLIGIETARMYTYYA 301 Query: 337 AVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQI 396 A + A A ++AK +A++ F NQA+Q+HGGYGY++++ V++ +RD +++QI Sbjct: 302 AWLADQGLPHAHA-SAIAKAYASEIAFEAANQAIQIHGGYGYVREFPVEKLLRDVKLNQI 360 Query: 397 LEGSNEVMRILISRSLL 413 EG+NE+ R++I+R +L Sbjct: 361 YEGTNEIQRLIIARHIL 377 >1IVH-A nrPDB Length = 394 Score = 458 bits (1180), Expect = e-129, Method: Composition-based stats. Identities = 127/390 (32%), Positives = 209/390 (53%), Gaps = 7/390 (1%) Query: 29 RSLTSCIDPSMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFP--VDVMRKAAQLGF 86 SL D GL+EEQ++ ++ F +AP E D+ F + ++ LG Sbjct: 1 HSLLPVDDAINGLSEEQRQLRQTMAKFLQEHLAPKAQEIDRSNEFKNLREFWKQLGNLGV 60 Query: 87 GGVYIQTDVGGSGLSRLDTSVIFEALATGCTSTTAYISIH-NMCAWMIDSFGNEEQRHKF 145 G+ GGSGL L+ ++ E ++ + H N+C + GNE Q+ K+ Sbjct: 61 LGITAPVQYGGSGLGYLEHVLVMEEISRASGAVGLSYGAHSNLCINQLVRNGNEAQKEKY 120 Query: 146 CPPLCTMEKFASYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMC 205 P L + E + ++EP +GSD S+ A+K+G+HYILNG+K +I+ ++D+ +V Sbjct: 121 LPKLISGEYIGALAMSEPNAGSDVVSMKLKAEKKGNHYILNGNKFWITNGPDADVLIVYA 180 Query: 206 RTG---GPGPKGISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSE 262 +T P +GI+ +VEKG PG S KK K+G T +IFEDC +P AN +G E Sbjct: 181 KTDLAAVPASRGITAFIVEKGMPGFSTSKKLDKLGMRGSNTCELIFEDCKIPAANILGHE 240 Query: 263 GQGFLIAVRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADM 322 +G + + GL+ R+ +A LG A + T +L+VR+ FG+ + Q +Q +ADM Sbjct: 241 NKGVYVLMSGLDLERLVLAGGPLGLMQAVLDHTIPYLHVREAFGQKIGHFQLMQGKMADM 300 Query: 323 ATRLVAARLMVRNAAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDY 382 TRL+A R V N A A E A C+ L++ + + +Q GG GY+ D+ Sbjct: 301 YTRLMACRQYVYNVAKACDEGHCTAK-DCAGVILYSAECATQVALDGIQCFGGNGYINDF 359 Query: 383 AVQQYVRDSRVHQILEGSNEVMRILISRSL 412 + +++RD+++++I G++EV R++I R+ Sbjct: 360 PMGRFLRDAKLYEIGAGTSEVRRLVIGRAF 389 >4U83-A nrPDB Length = 382 Score = 457 bits (1177), Expect = e-129, Method: Composition-based stats. Identities = 150/376 (39%), Positives = 224/376 (59%), Gaps = 3/376 (0%) Query: 39 MGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGS 98 M L + Q++ ++ A DFA +AP A D++ FP + + LGF G+ + GGS Sbjct: 8 MLLTDTQEQIREAARDFAQERLAPGAAARDREHAFPRAELTEMGALGFLGMLAPEEWGGS 67 Query: 99 GLSRLDTSVIFEALATGCTSTTAYISIHNMCA-WMIDSFGNEEQRHKFCPPLCTMEKFAS 157 L + ++ E +A G + + +S+H+ I FG E+Q+ +F P + E Sbjct: 68 DLDMVAYALALEEIAAGDGACSTIVSVHSSVGCMPILRFGTEDQKRRFLPKMACGEWIGG 127 Query: 158 YCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTG-GPGPKGIS 216 + LTEP +GSDA++L T A+ GDHY+++GSK FI+ ++ +V T G KGIS Sbjct: 128 FALTEPQAGSDASALKTRARLDGDHYVIDGSKQFITSGKNGNVVIVFAVTDPAAGKKGIS 187 Query: 217 CIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGG 276 +V TPG E K+G +S T A+ F + VPV NR+G+EG+G+ IA+ L GG Sbjct: 188 AFIVPTDTPGYEVMSVEHKLGQHSSDTCALGFTNMRVPVENRLGAEGEGYKIALANLEGG 247 Query: 277 RINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNA 336 RI IA+ ++G A A+ RD+ R FG+P+ +Q + F LADMATR+ AR MV +A Sbjct: 248 RIGIAAQAVGMARAAFEAARDYARERITFGKPIIEHQAVAFRLADMATRIETARQMVLHA 307 Query: 337 AVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQI 396 A AL+E K + SMAKL A++ +C+ A+Q+HGGYGYL DY V++ RD RV QI Sbjct: 308 A-ALREAGKPCLTEASMAKLVASEMAEQVCSAAIQIHGGYGYLADYPVERIYRDVRVCQI 366 Query: 397 LEGSNEVMRILISRSL 412 EG+++V R++I+R L Sbjct: 367 YEGTSDVQRLVIARGL 382 >6FAH-C nrPDB Length = 379 Score = 456 bits (1173), Expect = e-129, Method: Composition-based stats. Identities = 145/380 (38%), Positives = 228/380 (60%), Gaps = 4/380 (1%) Query: 39 MGLNEEQKEFQKVAFDFAAREMAPNM-AEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGG 97 M +E+ K +K+A DFA +E+ + E ++ FP +++ K A+ GF G+ I +GG Sbjct: 1 MYFSEQNKMIRKLARDFAEKELTTEILDEVEESGEFPQEILDKMAKFGFFGIKIPKSLGG 60 Query: 98 SGLSRLDTSVIFEALATGCTSTTAYISI-HNMCAWMIDSFGNEEQRHKFCPPLCTMEKFA 156 SG + + E A + Y+S +++ + G EEQ K+ P+ T +K Sbjct: 61 SGGDHMSYVICMEEFARVSGVASVYLSSPNSLAGGPLLLSGTEEQIEKYLKPIITGKKKL 120 Query: 157 SYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTG-GPGPKGI 215 ++ LTEPG+GSDA + T+A GD+Y+LNG K FI+ A D V+ +T G +GI Sbjct: 121 AFALTEPGAGSDAGGMSTTAVDMGDYYLLNGRKTFITMAPLCDDAVIYAKTDMSKGTRGI 180 Query: 216 SCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNG 275 S +V+ + G+S GK E K+G T +I ED VP NR+G +GF A++ L+ Sbjct: 181 SAFIVDLKSEGVSMGKNEHKMGLIGCATSDIIMEDVKVPKENRLGEVNKGFSNAMKTLDV 240 Query: 276 GRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRN 335 GR+ +AS S+G A ++ + RKQFG+ +A Q + F +ADMAT+L AA+L+V N Sbjct: 241 GRLGVASQSIGVAQGALDEAIKYAKERKQFGKRIADFQAIAFMIADMATKLEAAKLLVYN 300 Query: 336 AAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQ 395 AA +L + +K+A SMAK +A++ C IC +A+Q+HGGYGY+K+Y V++ RD RV Sbjct: 301 AA-SLMDNKKNATKEASMAKFYASEICNEICAKAVQIHGGYGYIKEYKVERMYRDCRVFT 359 Query: 396 ILEGSNEVMRILISRSLLQE 415 I EG+++V +++IS LL++ Sbjct: 360 IYEGTSQVQQMVISGMLLKK 379 >3MDE-A nrPDB Length = 385 Score = 445 bits (1145), Expect = e-125, Method: Composition-based stats. Identities = 133/381 (34%), Positives = 215/381 (56%), Gaps = 5/381 (1%) Query: 37 PSMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVG 96 S L E+QKEFQ A FA E+ P AE+D+ +PV ++++A +LG +I G Sbjct: 2 FSFELTEQQKEFQATARKFAREEIIPVAAEYDRTGEYPVPLLKRAWELGLMNTHIPESFG 61 Query: 97 GSGLSRLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSFGNEEQRHKFCPPLCTMEKFA 156 G GL +D+ +I E LA GCT I + + + GN +Q+ K+ + Sbjct: 62 GLGLGIIDSCLITEELAYGCTGVQTAIEANTLGQVPLIIGGNYQQQKKYLGRMTEEPLMC 121 Query: 157 SYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTG----GPGP 212 +YC+TEPG+GSD A + T A+K+GD YI+NG K +I+ G+++ Y ++ R+ P Sbjct: 122 AYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPAS 181 Query: 213 KGISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRG 272 K + +VE TPG+ G+KE +G TR ++FED VP N + EG GF IA+ Sbjct: 182 KAFTGFIVEADTPGVQIGRKEINMGQRCSDTRGIVFEDVRVPKENVLTGEGAGFKIAMGT 241 Query: 273 LNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLM 332 + R +A+ ++G A ++ + RK FG+ LA +Q + F LADMA ++ ARL Sbjct: 242 FDKTRPPVAAGAVGLAQRALDEATKYALERKTFGKLLAEHQGISFLLADMAMKVELARLS 301 Query: 333 VRNAAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSR 392 + AA + R++ S+AK +A D + A+Q+ GG G+ +Y V++ +RD++ Sbjct: 302 YQRAAWEIDSGRRNTY-YASIAKAYAADIANQLATDAVQVFGGNGFNTEYPVEKLMRDAK 360 Query: 393 VHQILEGSNEVMRILISRSLL 413 ++QI EG+ ++ RI+I+R + Sbjct: 361 IYQIYEGTAQIQRIIIAREHI 381 >4O5M-A nrPDB Length = 390 Score = 445 bits (1145), Expect = e-125, Method: Composition-based stats. Identities = 127/380 (33%), Positives = 205/380 (53%), Gaps = 3/380 (0%) Query: 38 SMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGG 97 + GL EE + + FA +AP AE D+ FP+ + R+ +LG G+ D GG Sbjct: 10 NFGLGEEIEALRDTVRRFAESRIAPLAAETDRNNQFPMHLWREFGELGVLGITAPEDYGG 69 Query: 98 SGLSRLDTSVIFEALATGCTSTTAYISIH-NMCAWMIDSFGNEEQRHKFCPPLCTMEKFA 156 +G+ L + E ++ S H N+C I G+ EQR K+ P L + E Sbjct: 70 AGMGYLAHCIAMEEISRASASIGLSYGAHSNLCVNQITRNGSPEQRAKYLPKLISGEHVG 129 Query: 157 SYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTG-GPGPKGI 215 + ++EPG+GSD S+ +A+K+GD Y+LNG+K +I+ ++D+ VV +T GP+GI Sbjct: 130 ALAMSEPGAGSDVVSMKLAAEKRGDRYVLNGNKMWITNGPDADVLVVYAKTDLSAGPRGI 189 Query: 216 SCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNG 275 S ++EKG G S +K K+G T ++FEDC VP N +G+EG+G + + GL+ Sbjct: 190 SAFIIEKGFKGFSTAQKLDKLGMRGSNTCELVFEDCEVPAENLLGTEGKGVNVLMSGLDY 249 Query: 276 GRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRN 335 R+ +A LG A + + +++ RKQF +P+ Q +Q LADM A+R V Sbjct: 250 ERVVLAGGPLGIMAACLDVVVPYVHERKQFDQPIGEFQLMQCKLADMYVTFNASRAYVYA 309 Query: 336 AAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQ 395 A A + + L++ + + QA+Q GG GY+ DY + +RD+++++ Sbjct: 310 VAAACD-RGETTRKDAAGCILYSAENATQMALQAIQSLGGNGYINDYPTGRLLRDAKLYE 368 Query: 396 ILEGSNEVMRILISRSLLQE 415 I G++E+ R+LI R L QE Sbjct: 369 IGAGTSEIRRMLIGRELFQE 388 >4M9A-A nrPDB Length = 385 Score = 443 bits (1139), Expect = e-125, Method: Composition-based stats. Identities = 139/373 (37%), Positives = 221/373 (59%), Gaps = 3/373 (0%) Query: 42 NEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGLS 101 E+Q+ A F A +APN A+WD++ P +V+ + +LGF G+ + D GGS Sbjct: 14 TEDQRMILDAARAFCAEVLAPNAAQWDRESHLPDEVVAQMGELGFLGMIVPADWGGSYTD 73 Query: 102 RLDTSVIFEALATGCTSTTAYISIHNMCA-WMIDSFGNEEQRHKFCPPLCTMEKFASYCL 160 + ++ E +A GC S +S+HN + ++G EQ+ ++ L + + ++ L Sbjct: 74 YVAYALALEEIAAGCASCATLVSVHNSVGCGPVLNYGTTEQKERWLRDLASGKTVGAFSL 133 Query: 161 TEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTG-GPGPKGISCIV 219 TEP +GS+A +L T A+ + +ILNGSK F++ + + +V T G +G+S V Sbjct: 134 TEPHAGSEAHNLRTRAELRDGKWILNGSKQFVTNGARAGLAIVFAMTDPDEGKRGLSAFV 193 Query: 220 VEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGGRIN 279 V TPG GK EKK+G + T + E+CA+P N +G G+G IA+ L GGRI Sbjct: 194 VPTDTPGFIVGKPEKKMGIRASDTCPITLENCAIPQENLLGKRGEGLKIALSNLEGGRIG 253 Query: 280 IASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNAAVA 339 IA+ + G A A+ R + R QFG+P+A +Q + LA+MAT++ AARL+ +AA Sbjct: 254 IAAQATGIARAAFDRARRYARERVQFGKPIAEHQAIAEKLANMATQINAARLLTHHAA-R 312 Query: 340 LQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQILEG 399 L+ ++ S AKLFA++ A+C+ A+Q+HGGYG+L DY V+++ RD+R+ QI EG Sbjct: 313 LRTAGLPCLSEASQAKLFASEMAEAVCSDAIQIHGGYGFLVDYEVERHYRDARITQIYEG 372 Query: 400 SNEVMRILISRSL 412 ++EV R++I+R L Sbjct: 373 TSEVQRMVIARQL 385 >1BUC-A nrPDB Length = 383 Score = 443 bits (1139), Expect = e-125, Method: Composition-based stats. Identities = 143/383 (37%), Positives = 220/383 (57%), Gaps = 7/383 (1%) Query: 38 SMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGG 97 L + Q++F K+A DF +++AP + E D K ++ +++ + LG G Y + GG Sbjct: 2 DFNLTDIQQDFLKLAHDFGEKKLAPTVTERDHKGIYDKELIDELLSLGITGAYFEEKYGG 61 Query: 98 SGLS---RLDTSVIFEALATGCTSTTAYISIH-NMCAWMIDSFGNEEQRHKFCPPLCTME 153 SG L + E LA +S ++CA I FG E Q+ KF PL Sbjct: 62 SGDDGGDVLSYILAVEELAKYDAGVAITLSATVSLCANPIWQFGTEAQKEKFLVPLVEGT 121 Query: 154 KFASYCLTEPGSGSDAASLLTSAKKQGDH-YILNGSKAFISGAGESDIYVVMCRTG-GPG 211 K ++ LTEP +G+DA+ T A K D Y LNGSK FI+ G +DIY+V T G Sbjct: 122 KLGAFGLTEPNAGTDASGQQTIATKNDDGTYTLNGSKIFITNGGAADIYIVFAMTDKSKG 181 Query: 212 PKGISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVR 271 GI+ ++E GTPG ++GKKE K+G ++ T ++F+D VP N +G EG+GF IA+ Sbjct: 182 NHGITAFILEDGTPGFTYGKKEDKMGIHTSQTMELVFQDVKVPAENMLGEEGKGFKIAMM 241 Query: 272 GLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARL 331 L+GGRI +A+ +LG A A++ ++ R QFG+PL Q + F LADM ++ AAR Sbjct: 242 TLDGGRIGVAAQALGIAEAALADAVEYSKQRVQFGKPLCKFQSISFKLADMKMQIEAARN 301 Query: 332 MVRNAAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDS 391 +V AA ++E K ++AK A+D + +A+Q+ GGYGY ++Y V +++RD+ Sbjct: 302 LVYKAACK-KQEGKPFTVDAAIAKRVASDVAMRVTTEAVQIFGGYGYSEEYPVARHMRDA 360 Query: 392 RVHQILEGSNEVMRILISRSLLQ 414 ++ QI EG+NEV ++ +LL+ Sbjct: 361 KITQIYEGTNEVQLMVTGGALLR 383 >3PFD-A nrPDB Length = 393 Score = 439 bits (1129), Expect = e-123, Method: Composition-based stats. Identities = 133/377 (35%), Positives = 211/377 (55%), Gaps = 1/377 (0%) Query: 39 MGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGS 98 L EE ++ A +E+AP AE D+K FP + + GF +++ + GG Sbjct: 17 FQLPEEHIALREAIRALAEKEIAPYAAEVDEKARFPEEALAALNSSGFSAIHVPEEYGGQ 76 Query: 99 GLSRLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSFGNEEQRHKFCPPLCTMEKFASY 158 G + T ++ E +A S + +++ + + G+EE + + P + + E ASY Sbjct: 77 GADSVATCIVIEEVARVDCSASLIPAVNKLGTMGLILRGSEELKKQVLPAVASGEAMASY 136 Query: 159 CLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTG-GPGPKGISC 217 L+E +GSDAAS+ T A GD +ILNGSK +I+ G+S Y VM T G GIS Sbjct: 137 ALSEREAGSDAASMRTRAVADGDDWILNGSKCWITNGGKSTWYTVMAVTDPDKGANGISA 196 Query: 218 IVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGGR 277 +V K G + G KE+K+G PT + FE+C +P IG G GF A+ L+ R Sbjct: 197 FMVHKDDEGFTVGPKERKLGIKGSPTTELYFENCRIPGDRIIGEPGTGFKTALATLDHTR 256 Query: 278 INIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNAA 337 I + ++G A ++ + RKQFG P++ NQ +QF LADMA ++ AARLMV +AA Sbjct: 257 PTIGAQAVGIAQGALDAAIAYTKERKQFGRPVSDNQGVQFMLADMAMKIEAARLMVYSAA 316 Query: 338 VALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQIL 397 + D + + +K FA+D + A+Q+ GGYGY +D+ V++ +RD+++ QI Sbjct: 317 ARAERGEGDLGFISAASKCFASDVAMEVTTDAVQLFGGYGYTQDFPVERMMRDAKITQIY 376 Query: 398 EGSNEVMRILISRSLLQ 414 EG+N++ R+++SR+LL+ Sbjct: 377 EGTNQIQRVVMSRALLR 393 >2JIF-A nrPDB Length = 404 Score = 430 bits (1106), Expect = e-121, Method: Composition-based stats. Identities = 136/379 (35%), Positives = 208/379 (54%), Gaps = 4/379 (1%) Query: 36 DPSMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDV 95 P +E+ + FA ++AP ++ D+ V++ Q G G+ + + Sbjct: 24 APLQTFTDEEMMIKSSVKKFAQEQIAPLVSTMDENSKMEKSVIQGLFQQGLMGIEVDPEY 83 Query: 96 GGSGLSRLDTSVIFEALATGCTSTTAYISIHN-MCAWMIDSFGNEEQRHKFCPPLCTMEK 154 GG+G S L T ++ E LA S + I N + +I G EEQ+ + P L T EK Sbjct: 84 GGTGASFLSTVLVIEELAKVDASVAVFCEIQNTLINTLIRKHGTEEQKATYLPQLTT-EK 142 Query: 155 FASYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGGP-GPK 213 S+CL+E G+GSD+ +L T A K+GD+Y+LNGSK +IS A + +++VM G K Sbjct: 143 VGSFCLSEAGAGSDSFALKTRADKEGDYYVLNGSKMWISSAEHAGLFLVMANVDPTIGYK 202 Query: 214 GISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGL 273 GI+ +V++ TPGL GK E K+G + T + FE+ VP AN +G G G+ A+ L Sbjct: 203 GITSFLVDRDTPGLHIGKPENKLGLRASSTCPLTFENVKVPEANILGQIGHGYKYAIGSL 262 Query: 274 NGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMV 333 N GRI IA+ LG A T ++ R QFG+ L Q LQ +A +AT+L AARL+ Sbjct: 263 NEGRIGIAAQMLGLAQGCFDYTIPYIKERIQFGKRLFDFQGLQHQVAHVATQLEAARLLT 322 Query: 334 RNAAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRV 393 NAA L E K + SMAK +A++ ++ ++ GG GY KDY V++Y RD+++ Sbjct: 323 YNAA-RLLEAGKPFIKEASMAKYYASEIAGQTTSKCIEWMGGVGYTKDYPVEKYFRDAKI 381 Query: 394 HQILEGSNEVMRILISRSL 412 I EG++ + I++ + Sbjct: 382 GTIYEGASNIQLNTIAKHI 400 >4IRN-A nrPDB Length = 416 Score = 429 bits (1104), Expect = e-121, Method: Composition-based stats. Identities = 116/403 (28%), Positives = 205/403 (50%), Gaps = 5/403 (1%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELF 73 G +P G + TG + + + N +Q +F+K FA + + ++ + D++E+F Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSEFDFAWNSQQIQFRKKVIQFAQQSLISDLIKNDKEEIF 72 Query: 74 PVDVMRKAAQLGFGGVYIQTDVGGSGLSRLDTSVIFEALATGCTSTTAYISIHN---MCA 130 D +K ++ G G I GG L L T+ + L GC +++ C Sbjct: 73 NRDAWQKCSEFGVHGWPIPARYGGQELDILTTAYALQGLGYGCKDNGLIFAMNAHIWACE 132 Query: 131 WMIDSFGNEEQRHKFCPPLCTMEKFASYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKA 190 + +FG EEQ+ K+ P LC AS+ TEP +GSD SL T+A+K GD YILNG K Sbjct: 133 MPLLTFGTEEQKEKYLPLLCRGGWIASHAATEPQAGSDIYSLKTTAQKDGDKYILNGYKH 192 Query: 191 FISGAGESDIYVVMCRTGGP-GPKGISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFE 249 +++ +D++++ G +G++ ++EK TPGL K K+G + + E Sbjct: 193 YVTNGTIADLFIIFATIDPSLGKEGLTTFMIEKDTPGLILSKPISKMGMRTAEVPELRLE 252 Query: 250 DCAVPVANRIGSEGQGFLIAVRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPL 309 +C V ANR+G EG G I + R I + ++G + + + KQFG+ + Sbjct: 253 NCEVSAANRLGEEGTGLAIFNHSMEWERGFILAAAVGTMERLLEQSIRYARSHKQFGQAI 312 Query: 310 ASNQYLQFTLADMATRLVAARLMVRNAAVALQEERKDAVALCSMAKLFATDECFAICNQA 369 Q + L +M RL A+ + A ++E ++ A+ SMA L+ ++ C +A Sbjct: 313 GKFQLVANKLVEMKLRLENAKAYLYKVAW-MKENKQMALLEASMANLYISEAWVQSCLEA 371 Query: 370 LQMHGGYGYLKDYAVQQYVRDSRVHQILEGSNEVMRILISRSL 412 +++HG YGYL + +++ +RD+ + G++E+ R++I++ L Sbjct: 372 IEIHGAYGYLTNTELERELRDAIASKFYSGTSEIQRVVIAKFL 414 >4KTO-A nrPDB Length = 410 Score = 426 bits (1095), Expect = e-119, Method: Composition-based stats. Identities = 126/380 (33%), Positives = 201/380 (52%), Gaps = 3/380 (0%) Query: 38 SMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGG 97 + L EE + FA+ +AP + D+ FP+ + R+ +LG G+ GG Sbjct: 30 NFALGEEIDALRASVRRFASERIAPLADDADRSNAFPMSLWREMGELGLLGITADEAHGG 89 Query: 98 SGLSRLDTSVIFEALATGCTSTTAYISIH-NMCAWMIDSFGNEEQRHKFCPPLCTMEKFA 156 +GL L V E ++ S H N+C I+ G Q+ ++ P L + E Sbjct: 90 AGLGYLAHCVAMEEISRASASVGLSYGAHSNLCVNQINRNGKPAQKSRYLPKLISGEHVG 149 Query: 157 SYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTG-GPGPKGI 215 + ++EPG+GSD S+ A K+GD Y+LNGSK +I+ ++D+ VV +T GP+GI Sbjct: 150 ALAMSEPGAGSDVVSMKLKADKRGDRYVLNGSKMWITNGPDADVLVVYAKTDPAAGPRGI 209 Query: 216 SCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNG 275 + +VEK PG S G+K K+G T +IF DC VP N +G G+G + + GL+ Sbjct: 210 TAFLVEKAFPGFSAGQKLDKLGMRGSNTSELIFTDCEVPEENVLGGVGEGVKVLMSGLDY 269 Query: 276 GRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRN 335 R+ +++ LG A + + +L+ RKQFG+P+ Q +Q LADM + AAR V Sbjct: 270 ERVVLSAGPLGIMAACLDVVVPYLHERKQFGQPIGEFQLMQGKLADMYVTMNAARAYVYA 329 Query: 336 AAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQ 395 A A + A + L+A ++ A+ +A+Q GG GY DY + +RD+++++ Sbjct: 330 VAAACD-RGETARKDAAGCILYAAEKATAMALEAIQALGGNGYTNDYPAGRLLRDAKLYE 388 Query: 396 ILEGSNEVMRILISRSLLQE 415 I G++E+ R+LI R L E Sbjct: 389 IGAGTSEIRRMLIGRELFAE 408 >2PG0-A nrPDB Length = 385 Score = 423 bits (1088), Expect = e-119, Method: Composition-based stats. Identities = 128/376 (34%), Positives = 201/376 (53%), Gaps = 4/376 (1%) Query: 40 GLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSG 99 L EE F+ F +E P+ +W+++ + P K + GF ++ GG Sbjct: 9 YLREEHHMFRAAFRKFLEKEAYPHYNDWEKRGIIPRSFWAKMGENGFLCPWVDEKYGGLN 68 Query: 100 LSRLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSFGNEEQRHKFCPPLCTMEKFASYC 159 + VI E L +S +++ I S+G EEQ+ K+ P T E + Sbjct: 69 ADFAYSVVINEELEKVGSSLVGIGLHNDIVTPYIASYGTEEQKQKWLPKCVTGELITAIA 128 Query: 160 LTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGG---PGPKGIS 216 +TEPG+GSD A++ T+A K GD+YI+NG K FI+ +D+ VV C+T P +GIS Sbjct: 129 MTEPGAGSDLANISTTAVKDGDYYIVNGQKTFITNGIHADLIVVACKTDPQAKPPHRGIS 188 Query: 217 CIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGG 276 +VVE+ TPG + G+K +KVG ++Q T + F+D VP N +G EG+GF + L Sbjct: 189 LLVVERDTPGFTRGRKLEKVGLHAQDTAELFFQDAKVPAYNLLGEEGKGFYYLMEKLQQE 248 Query: 277 RINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNA 336 R+ +A + AA LT+ ++ R FG+ ++ Q +QF LA+MAT + R V Sbjct: 249 RLVVAIAAQTAAEVMFSLTKQYVKQRTAFGKRVSEFQTVQFRLAEMATEIALGRTFVDRV 308 Query: 337 AVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQI 396 + K V SMAK + T+ + +A+Q+HGGYGY+++Y + + RD V I Sbjct: 309 -IEEHMAGKQIVTEVSMAKWWITEMAKRVAAEAMQLHGGYGYMEEYEIARRYRDIPVSAI 367 Query: 397 LEGSNEVMRILISRSL 412 G+NE+M+ +I+R L Sbjct: 368 YAGTNEMMKTIIARQL 383 >4IV6-A nrPDB Length = 388 Score = 415 bits (1066), Expect = e-116, Method: Composition-based stats. Identities = 127/380 (33%), Positives = 209/380 (55%), Gaps = 6/380 (1%) Query: 38 SMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGG 97 SM L E++ K DF +++ P + E + +P +++ ++G G+ I G Sbjct: 4 SMALTAEEETIVKTVHDFVEKQVKPVVRELEHANTYPEELIETMKEIGIFGLAIPEPYGF 63 Query: 98 SGLSRLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSFGNEEQRHKFCPPLCTMEKFAS 157 +S + E LA G S + H + + ++ FG EEQ+ K+ P + T E A+ Sbjct: 64 GAVSMPCYVQVAEELARGWMSLAGAMGGHTVVSKLLLLFGTEEQKQKYLPRMATGELRAT 123 Query: 158 YCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGG---PGPKG 214 LTEPG GSD ++ T A++ GD Y++NGSK +IS A SD+ +MC+T P KG Sbjct: 124 MALTEPGGGSDLQAMRTVARRDGDDYVINGSKTWISNARRSDLVALMCKTDPDAQPAHKG 183 Query: 215 ISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIG-SEGQGFLIAVRGL 273 +S ++VEK PG + K+G+ + + F D VPV++ +G EG+GF ++GL Sbjct: 184 VSILLVEK-VPGFDVSRDLPKLGYKGVESCELNFTDARVPVSSLLGDDEGRGFAQMMKGL 242 Query: 274 NGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMV 333 GR+ +A+ + G A A+ + R+ FG+P+ +Q + LADM T+L AAR ++ Sbjct: 243 EVGRLQVAARATGVARAAFEDALRYSQERESFGKPIWQHQSVGNMLADMGTKLYAARSLL 302 Query: 334 RNAAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRV 393 +AA + MAKLFA++ I A+++HGGYGY +Y V++Y RD+ + Sbjct: 303 LSAAEKFD-AGQRCDMEAGMAKLFASETAMQIALDAVRVHGGYGYSTEYDVERYFRDAPL 361 Query: 394 HQILEGSNEVMRILISRSLL 413 + EG+NE+ R +I++ L+ Sbjct: 362 MIVGEGTNEIQRNVIAKQLV 381 >2DVL-A nrPDB Length = 372 Score = 412 bits (1059), Expect = e-115, Method: Composition-based stats. Identities = 136/377 (36%), Positives = 221/377 (58%), Gaps = 6/377 (1%) Query: 39 MGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGS 98 M L +EQ+ A + P E+D+K +P ++ A+LG G+ + GG Sbjct: 1 MTLTQEQRLVLDAVRRVAREVLYPLAPEYDRKAEYPWPQLKALAELGLLGMTTPEEWGGV 60 Query: 99 GLSRLDTSVIFEALATGCTSTTAYISIHN-MCAWMIDSFGNEEQRHKFCPPLCTMEKFAS 157 GL + ++ E LA S +S+ + + +M+ FG+E Q+ ++ PL E + Sbjct: 61 GLDSVTWALALEELAAADPSVAVIVSVTSGLPQYMLLRFGSEAQKRRYLVPLARGEWIGA 120 Query: 158 YCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGGPGPKGISC 217 +CLTEP +GSDA SL A++ ++LNG K++I+ AG + +YVVM RT KGIS Sbjct: 121 FCLTEPQAGSDAKSLRAEARRVKGGFVLNGVKSWITSAGHAHLYVVMARTE----KGISA 176 Query: 218 IVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGGR 277 +VEKGTPGLSFG+ E+K+G ++ T V E+ VP N +G EG+G A+ GL+ GR Sbjct: 177 FLVEKGTPGLSFGRPEEKMGLHAAHTAEVRLEEVFVPEENLLGEEGRGLAYALAGLDSGR 236 Query: 278 INIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNAA 337 + +A+ ++G A + + + + R+QFG+ L +Q + F +ADM ++ AAR +V AA Sbjct: 237 VGVAAQAVGIARGAFEIAKAYAEEREQFGKKLKEHQAIAFKIADMHVKIAAARALVLEAA 296 Query: 338 VALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQIL 397 ++ + S AKLFA+ + +A+Q+ GGYGY +DY V++Y RD++V +I Sbjct: 297 -RKKDRGERFTLEASAAKLFASAAAVEVTREAVQVLGGYGYHRDYRVERYYRDAKVTEIY 355 Query: 398 EGSNEVMRILISRSLLQ 414 EG++E+ R++I+R L + Sbjct: 356 EGTSEIQRLVIARELYR 372 >3MPI-A nrPDB Length = 397 Score = 403 bits (1035), Expect = e-112, Method: Composition-based stats. Identities = 115/378 (30%), Positives = 203/378 (53%), Gaps = 7/378 (1%) Query: 38 SMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFP-VDVMRKAAQLGFGGVYIQTDVG 96 L++E + QK +F +++ P +WD + FP + +R +LGF G I + G Sbjct: 2 DFNLSKELQMLQKEVRNFVNKKIVPFADQWDNENHFPYEEAVRPMGELGFFGTVIPEEYG 61 Query: 97 GSGLS--RLDTSVIFEALATGCTSTTAYISIHNM-CAWMIDSFGNEEQRHKFCPPLCTME 153 G G+ L ++ E +A G ++ +++ + CA+ I ++G+E + K+ P L + E Sbjct: 62 GEGMDQGWLAAMIVTEEIARGSSALRVQLNMEVLGCAYTILTYGSEALKKKYVPKLSSAE 121 Query: 154 KFASYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTG-GPGP 212 + +TEP +GSD ++ ++A+ +GDH++LNGSK +IS A ++D+ + T G Sbjct: 122 FLGGFGITEPDAGSDVMAMSSTAEDKGDHWLLNGSKTWISNAAQADVLIYYAYTDKAAGS 181 Query: 213 KGISCIVV-EKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVR 271 +G+S V+ + PG+ E K+G ++ PT + ++ VP N +G G G I Sbjct: 182 RGLSAFVIEPRNFPGIKTSNLE-KLGSHASPTGELFLDNVKVPKENILGKPGDGARIVFG 240 Query: 272 GLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARL 331 LN R++ A+ +G A A + + N R+QFG+P+ Q Q +A MA + AARL Sbjct: 241 SLNHTRLSAAAGGVGLAQACLDAAIKYCNERRQFGKPIGDFQMNQDMIAQMAVEVEAARL 300 Query: 332 MVRNAAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDS 391 + AA A E R + +MAK A + N A+++ G YGY +Y V ++ RD+ Sbjct: 301 LAYKAAAAKDEGRLNNGLDVAMAKYAAGEAVSKCANYAMRILGAYGYSTEYPVARFYRDA 360 Query: 392 RVHQILEGSNEVMRILIS 409 + ++EGS + +++I+ Sbjct: 361 PTYYMVEGSANICKMIIA 378 >3GNC-A nrPDB Length = 399 Score = 402 bits (1034), Expect = e-112, Method: Composition-based stats. Identities = 105/372 (28%), Positives = 182/372 (48%), Gaps = 3/372 (0%) Query: 41 LNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGL 100 L ++++ + A +A ++AP + E + E + R+ ++G G I GG GL Sbjct: 22 LADDERMVRDAAHAYAQGKLAPRVTEAFRHETTDAAIFREMGEIGLLGPTIPEQYGGPGL 81 Query: 101 SRLDTSVIFEALATGCTSTTAYISIHN-MCAWMIDSFGNEEQRHKFCPPLCTMEKFASYC 159 + +I + + + +S+ + + I FG++ Q+ K+ P L T E + Sbjct: 82 DYVSYGLIAREVERVDSGYRSMMSVQSSLVMVPIFEFGSDAQKEKYLPKLATGEWIGCFG 141 Query: 160 LTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGGPGPKGISCIV 219 LTEP GSD S++T A+K Y L+GSK +I+ + +D++VV + G I + Sbjct: 142 LTEPNHGSDPGSMVTRARKVPGGYSLSGSKMWITNSPIADVFVVWAKLDEDGRDEIRGFI 201 Query: 220 VEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGGRIN 279 +EKG GLS KVG + T ++ ++ VP N + +G LN R Sbjct: 202 LEKGCKGLSAPAIHGKVGLRASITGEIVLDEAFVPEENIL-PHVKGLRGPFTCLNSARYG 260 Query: 280 IASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNAAVA 339 IA +LGAA + + R ++ RKQFG PLA+NQ +Q LADM T + V Sbjct: 261 IAWGALGAAESCWHIARQYVLDRKQFGRPLAANQLIQKKLADMQTEITLGLQGVLRLG-R 319 Query: 340 LQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQILEG 399 +++E AV + S+ K + + I A M GG G ++ V +++ + V EG Sbjct: 320 MKDEGTAAVEITSIMKRNSCGKALDIARLARDMLGGNGISDEFGVARHLVNLEVVNTYEG 379 Query: 400 SNEVMRILISRS 411 ++++ +++ R+ Sbjct: 380 THDIHALILGRA 391 >3NF4-A nrPDB Length = 387 Score = 400 bits (1027), Expect = e-112, Method: Composition-based stats. Identities = 124/373 (33%), Positives = 208/373 (55%), Gaps = 2/373 (0%) Query: 42 NEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGLS 101 ++E E ++ + A + + P + ++ E +P V + G + + GG G Sbjct: 17 SQEAAELIELTREIADKVLDPIVDRHEKDETYPEGVFEQLGAAGLLSLPQPEEWGGGGQP 76 Query: 102 RLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSFGNEEQRHKFCPPLCTMEKFASYCLT 161 + E +A S +S+H++ + + FG EEQ+ ++ P + + E+ +Y L+ Sbjct: 77 YEVYLQVLEEIAARWASVAVAVSVHSLSSHPLLVFGTEEQKKRWLPGMLSGEQIGAYSLS 136 Query: 162 EPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGGPGPKGISCIVVE 221 EP +GSDAA+L +A Y++NGSK++I+ G++D Y + RT G G +G+SC +V Sbjct: 137 EPQAGSDAAALRCAATPTDGGYVINGSKSWITHGGKADFYTLFART-GEGSRGVSCFLVP 195 Query: 222 KGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGGRINIA 281 PGLSFGK E+K+G ++ PT + +++ + RIG EGQG IA L+ GR+ IA Sbjct: 196 ADQPGLSFGKPEEKMGLHAVPTTSAFYDNARIDADRRIGEEGQGLQIAFSALDSGRLGIA 255 Query: 282 SCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNAAVALQ 341 + + G A A++ + N R FG + +Q L F LADMA + AR +AA Sbjct: 256 AVATGLAQAALDEAVAYANERTAFGRKIIDHQGLGFLLADMAAAVATARATYLDAARRRD 315 Query: 342 EERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQILEGSN 401 + R S+AKL ATD + A+Q+ GG GY +DY V++Y+R++++ QI EG+N Sbjct: 316 QGR-PYSQQASIAKLTATDAAMKVTTDAVQVFGGVGYTRDYRVERYMREAKIMQIFEGTN 374 Query: 402 EVMRILISRSLLQ 414 ++ R++I+R L + Sbjct: 375 QIQRLVIARGLTR 387 >2Z1Q-A nrPDB Length = 577 Score = 399 bits (1026), Expect = e-111, Method: Composition-based stats. Identities = 136/412 (33%), Positives = 216/412 (52%), Gaps = 22/412 (5%) Query: 23 LVQTGHRSLTSCIDPSMG---LNEEQKEFQKVAFDFAAREMAPNMAEWDQKE-LFPVDVM 78 L Q G L + +E KE + F RE+ P + + E V +M Sbjct: 7 LWQKGGGWLLEVPERVYTPEDFDESVKEIARTTRTFVEREVLPLLERMEHGELELNVPLM 66 Query: 79 RKAAQLGFGGVYIQTDVGGSGLSRLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSFGN 138 RKA +LG + + + GG L ++ ++V+ E L+ + Y + ++ + FG Sbjct: 67 RKAGELGLLAIDVPEEYGGLDLPKVISTVVAEELSGSGGFSVTYGAHTSIGTLPLVYFGT 126 Query: 139 EEQRHKFCPPLCTMEKFASYCLTEPGSGSDAASLLTSAK--KQGDHYILNGSKAFISGAG 196 EEQ+ K+ P L + E A+YCLTEPGSGSDA + T A + G HYILNG K +IS AG Sbjct: 127 EEQKRKYLPKLASGEWIAAYCLTEPGSGSDALAAKTRATLSEDGKHYILNGVKQWISNAG 186 Query: 197 ESDIYVVMCRTGGPGPKGISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVA 256 + ++ V + G + + +VE+ TPGLSFG +EKK+G + TR VI ED VPV Sbjct: 187 FAHLFTVFAKVDG---EHFTAFLVERDTPGLSFGPEEKKMGIKASSTRQVILEDVKVPVE 243 Query: 257 NRIGSEGQGFLIAVRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQ 316 N +G G+G IA LN GR + + ++G A ++ L+ + R QFG P+ +Q Sbjct: 244 NVLGEIGKGHKIAFNVLNVGRYKLGAGAVGGAKRALELSAQYATQRVQFGRPIGRFGLIQ 303 Query: 317 FTLADMATRLVAARLMVRNAAVALQE-------------ERKDAVALCSMAKLFATDECF 363 L +MA+R+ AA V + E ++ S+ K+ ++ Sbjct: 304 QKLGEMASRIYAAESAVYRTVGLIDEALLGKKGPEAVMAGIEEYAVEASIIKVLGSEVLD 363 Query: 364 AICNQALQMHGGYGYLKDYAVQQYVRDSRVHQILEGSNEVMRILISRSLLQE 415 + ++ +Q+HGGYGY ++Y +++ RD+R+++I EG+NE+ R+LI LL+ Sbjct: 364 YVVDEGVQIHGGYGYSQEYPIERAYRDARINRIFEGTNEINRLLIPGMLLRR 415 >3OWA-A nrPDB Length = 597 Score = 392 bits (1007), Expect = e-109, Method: Composition-based stats. Identities = 128/397 (32%), Positives = 216/397 (54%), Gaps = 26/397 (6%) Query: 41 LNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVD--VMRKAAQLGFGGVYIQTDVGGS 98 + E K K DF E+ P + E+ ++ F ++++A +LG G + + GG Sbjct: 33 FSSEHKMIAKTTEDFIVNEVLPEL-EYLEQHEFDRSVRLLKEAGELGLLGADVPEEYGGI 91 Query: 99 GLSRLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSFGNEEQRHKFCPPLCTMEKFASY 158 GL ++ +++I E + + + + + I FGNEEQ+ K+ P L T EK A+Y Sbjct: 92 GLDKVSSALIAEKFSRAGGFAITHGAHVGIGSLPIVLFGNEEQKKKYLPLLATGEKLAAY 151 Query: 159 CLTEPGSGSDAASLLTSAK--KQGDHYILNGSKAFISGAGESDIYVVMCRTGGPGPKGIS 216 LTEPGSGSDA T+A+ +G HY+LNG K +I+ + +D+++V + G + S Sbjct: 152 ALTEPGSGSDALGAKTTARLNAEGTHYVLNGEKQWITNSAFADVFIVYAKIDG---EHFS 208 Query: 217 CIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGG 276 +VEK G+S +EKK+G TR +I ED VP N +G G+G +IA LN G Sbjct: 209 AFIVEKDYAGVSTSPEEKKMGIKCSSTRTLILEDALVPKENLLGEIGKGHIIAFNILNIG 268 Query: 277 RINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVR-- 334 R + ++G+A +V ++ + N R+QF +P+A +Q LA+MA + AA V Sbjct: 269 RYKLGVGTVGSAKRAVEISAQYANQRQQFKQPIARFPLIQEKLANMAAKTYAAESSVYRT 328 Query: 335 ------NAAVALQEERKDAVA----------LCSMAKLFATDECFAICNQALQMHGGYGY 378 + +EE KD A CS+ K+F ++ ++ +Q+HGGYG+ Sbjct: 329 VGLFESRMSTLSEEEVKDGKAVAASIAEYAIECSLNKVFGSEVLDYTVDEGVQIHGGYGF 388 Query: 379 LKDYAVQQYVRDSRVHQILEGSNEVMRILISRSLLQE 415 + +Y +++ RDSR+++I EG+NE+ R+++ + L++ Sbjct: 389 MAEYEIERMYRDSRINRIFEGTNEINRLIVPGTFLRK 425 >2EBA-A nrPDB Length = 385 Score = 389 bits (1000), Expect = e-108, Method: Composition-based stats. Identities = 99/374 (26%), Positives = 181/374 (48%), Gaps = 7/374 (1%) Query: 41 LNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGL 100 L E+KE QK A F +E P++ +W ++ +FP ++ + A+LGF G + + GG+G+ Sbjct: 11 LTPEEKEVQKAARRFLEKEALPHIRDWWEEGVFPTHLIPRFAELGFLGPTLPPEYGGAGV 70 Query: 101 SRLDTSVIFEALATGCTSTTAYISIH-NMCAWMIDSFGNEEQRHKFCPPLCTMEKFASYC 159 S +I L + +++S+ ++ + I ++G+EEQ+ +F P L E + Sbjct: 71 SSAAYGLICYELERVDSGLRSFVSVQSSLVMYPIYAYGSEEQKREFLPKLARGEMVGCFG 130 Query: 160 LTEPGSGSDA-ASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGGPGPKGISCI 218 LTEP GSD ++ T A+++GD ++LNG+K +I+ + + V+ + G + Sbjct: 131 LTEPDGGSDPYGNMKTRARREGDTWVLNGTKMWITNGNLAHLAVIWAKDEG---GEVLGF 187 Query: 219 VVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGGRI 278 +V TPG + ++K+ + T ++ E+ VP + R+ + G + L R Sbjct: 188 LVPTDTPGFQAREVKRKMSLRASVTSELVLEEVRVPESLRL-PKALGLKAPLSCLTQARF 246 Query: 279 NIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNAAV 338 IA ++GA A R FGEPLA Q +Q LA+M L++ Sbjct: 247 GIAWGAMGALEAVYEEAVAFAKSRSTFGEPLAKKQLVQAKLAEMLAWHTEG-LLLAWRLA 305 Query: 339 ALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQILE 398 L++E K A S+AK + A + GG G +Y +++ + E Sbjct: 306 RLKDEGKLTPAQVSLAKRQNVWKALQAARMARDILGGSGITLEYHAIRHMLNLETVYTYE 365 Query: 399 GSNEVMRILISRSL 412 G+++V +++ R + Sbjct: 366 GTHDVHTLVLGREI 379 >3R7K-A nrPDB Length = 403 Score = 389 bits (999), Expect = e-108, Method: Composition-based stats. Identities = 120/381 (31%), Positives = 203/381 (53%), Gaps = 3/381 (0%) Query: 34 CIDPSMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQT 93 + P E++ ++A F RE+AP +AEW+ P D+ AA++G G+ Sbjct: 22 VVAPEAWTTPERRALSQMARSFVEREIAPKLAEWEHVGEIPRDLHLNAAEVGLLGIGFPE 81 Query: 94 DVGGSGLSRLDTSVIFEALATGCTSTTAYISI--HNMCAWMIDSFGNEEQRHKFCPPLCT 151 +VGGSG + +D++++ EA+ ST ++ H + I + G++ ++ P Sbjct: 82 EVGGSGGNAIDSALVTEAILAAGGSTGVCAALFTHGIALPHIAANGSDALIERYVRPTLA 141 Query: 152 MEKFASYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGGPG 211 + S +TEPG+GSD A+L T A ++GD Y++NG+K FI+ +D RTGGPG Sbjct: 142 GKMIGSLGVTEPGAGSDVANLRTRAVREGDTYVVNGAKTFITSGVRADFVTTAVRTGGPG 201 Query: 212 PKGISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVR 271 G+S +V++K +PG ++ K+GW T + F D VP N +G+E GFL ++ Sbjct: 202 YGGVSLLVIDKNSPGFEVSRRLDKMGWRCSDTAELSFVDVRVPADNLVGAENSGFLQIMQ 261 Query: 272 GLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARL 331 R+ IA + A ++ L + R+ FG PL Q ++ LA+MA ++ A Sbjct: 262 QFQAERLGIAVQAYATAGRALDLAKSWARERETFGRPLTGRQIIRHKLAEMARQVDVACT 321 Query: 332 MVRNAAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDS 391 A + +D VA SMAK A C + N+A+Q+ GG GY+++ ++++ RD Sbjct: 322 YT-RAVMQRWLAGEDVVAEVSMAKNTAVYACDYVVNEAVQIFGGMGYMRESEIERHYRDC 380 Query: 392 RVHQILEGSNEVMRILISRSL 412 R+ I G+NE+M +I++ + Sbjct: 381 RILGIGGGTNEIMNEVIAKRI 401 >2CX9-A nrPDB Length = 387 Score = 383 bits (983), Expect = e-107, Method: Composition-based stats. Identities = 139/378 (36%), Positives = 217/378 (57%), Gaps = 7/378 (1%) Query: 43 EEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGLSR 102 E+++ +F E+AP AE D+ FP D++RK A+ G G + GG+GLS Sbjct: 9 AEERQVLGPFREFLKAEVAPGAAERDRTGAFPWDLVRKLAEFGVFGALVPEAYGGAGLST 68 Query: 103 LDTSVIFEALATGCTSTTAYISIHN-MCAWMIDSFGNEEQRHKFCPPLCTMEKFASYCLT 161 + + EA+A + ++ HN + I G+E Q+ F P L + E ++ LT Sbjct: 69 RLFARMVEAIAYYDGALALTVASHNSLATGHILLAGSEAQKEAFLPKLASGEALGAWGLT 128 Query: 162 EPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGGPG-----PKGIS 216 EPGSGSDAA+L T A+K + LNG+K FI+ + +YVVM RT P +GIS Sbjct: 129 EPGSGSDAAALKTKAEKVEGGWRLNGTKQFITQGSVAGVYVVMARTDPPPSPERKHQGIS 188 Query: 217 CIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGG 276 + GL G+KE+K+G + T +I ED VP +G G+GF +R L+GG Sbjct: 189 AFAFFRPERGLKVGRKEEKLGLTASDTAQLILEDLFVPEEALLGERGKGFYDVLRVLDGG 248 Query: 277 RINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNA 336 RI IA+ ++G A++ + R+ FG P+A + + F LA+ AT L AARL+ A Sbjct: 249 RIGIAAMAVGLGQAALDYALAYAKGREAFGRPIAEFEGVSFKLAEAATELEAARLLYLKA 308 Query: 337 AVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQI 396 A L++ + + AKLFA++ C++A+Q+ GGYGY+KDY V++Y RD+R+ +I Sbjct: 309 A-ELKDAGRPFTLEAAQAKLFASEAAVKACDEAIQILGGYGYVKDYPVERYWRDARLTRI 367 Query: 397 LEGSNEVMRILISRSLLQ 414 EG++E+++++I+R LL+ Sbjct: 368 GEGTSEILKLVIARRLLE 385 >3SF6-A nrPDB Length = 403 Score = 382 bits (981), Expect = e-106, Method: Composition-based stats. Identities = 98/402 (24%), Positives = 180/402 (44%), Gaps = 13/402 (3%) Query: 17 PGGLRVLVQTGHRSLTSCIDPSMG----LNEEQKEFQKVAFDFAAREMAPNMAEWDQKEL 72 PG + RS D +G L+ E++E + R + P++A W + Sbjct: 2 PGSMTNSAVAQPRSQRRGADDLIGINAVLSAEEREIRDTVRSVVQRRIKPHIASWYEDGE 61 Query: 73 FP-VDVMRKAAQLGFGGVYIQTDVGGSGLSRLDTSVIFEALATGCTSTTAYISIH-NMCA 130 P ++ + +LG G++++ G +G+S + + L G + + +S+ ++ Sbjct: 62 LPARELAVELGELGLLGMHLK-GYGCAGMSAVAYGLACLELEAGDSGIRSLVSVQGSLAM 120 Query: 131 WMIDSFGNEEQRHKFCPPLCTMEKFASYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKA 190 + I +FG++EQ+ ++ P + + + + LTEP GSD A + T A + GD +IL G+K Sbjct: 121 YAIHAFGSDEQKDQWLPDMASGHRIGCFGLTEPDHGSDPAGMRTRATRSGDDWILTGTKM 180 Query: 191 FISGAGESDIYVVMCRTGGPGPKGISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFED 250 +I+ +D+ VV RT +GI VV TPG + + K+ + T ++ + Sbjct: 181 WITNGSVADVAVVWARTD----EGIRGFVVPTDTPGFTANTIKSKMSLRASVTSELVLDG 236 Query: 251 CAVPVANRIGSEGQGFLIAVRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLA 310 +P + R+ +R LN R I +LGAA + + R+QF P+ Sbjct: 237 VRLPDSARLPG-ATSLGAPLRCLNEARFGIVFGALGAARDCLETALAYACSREQFDRPIG 295 Query: 311 SNQYLQFTLADMATRLVAARLMVRNAAVALQEERKDAVALCSMAKLFATDECFAICNQAL 370 Q Q LADM L+ + ++ + A S+ KL E I A Sbjct: 296 GFQLTQQKLADMTLEYGKGFLLALHLGRQ-KDAGELAPEQVSLGKLNNVREAIEIARTAR 354 Query: 371 QMHGGYGYLKDYAVQQYVRDSRVHQILEGSNEVMRILISRSL 412 + G G +Y V ++ + EG++E+ ++I ++L Sbjct: 355 TVLGASGITGEYPVMRHANNLESVLTYEGTSEMHTLIIGQAL 396 >3B96-A nrPDB Length = 587 Score = 379 bits (973), Expect = e-105, Method: Composition-based stats. Identities = 117/380 (30%), Positives = 194/380 (51%), Gaps = 11/380 (2%) Query: 41 LNEEQKEFQKVAFDFAAR--EMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGS 98 LNEEQ +F K + +R E + A+ D E+ + +LG G+ + +++GG Sbjct: 26 LNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELGGV 85 Query: 99 GLSRLDTSVIFEALATGCTSTTAYISIHNMCAW-MIDSFGNEEQRHKFCPPLCTMEKFAS 157 GL + + E + + H + I FG + Q+ K+ P L + E A+ Sbjct: 86 GLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAA 145 Query: 158 YCLTEPGSGSDAASLLTSAKK--QGDHYILNGSKAFISGAGESDIYVVMCRTGGPGP--- 212 +CLTEP SGSDAAS+ TSA G +Y LNGSK +IS G +DI+ V +T P Sbjct: 146 FCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATG 205 Query: 213 ---KGISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIA 269 + I+ VVE+G G++ G EKK+G + T V F+ VP N +G G GF +A Sbjct: 206 AVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVA 265 Query: 270 VRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAA 329 + LN GR +A+ G + DH R QFGE + + +Q LA M Sbjct: 266 MHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVT 325 Query: 330 RLMVRNAAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVR 389 M + + + D +++K+F ++ + + ++ +Q+ GG G++K+ V++ +R Sbjct: 326 ESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLR 385 Query: 390 DSRVHQILEGSNEVMRILIS 409 D R+ +I EG+N+++R+ ++ Sbjct: 386 DLRIFRIFEGTNDILRLFVA 405 >4W9U-A nrPDB Length = 395 Score = 378 bits (972), Expect = e-105, Method: Composition-based stats. Identities = 100/372 (26%), Positives = 170/372 (45%), Gaps = 4/372 (1%) Query: 41 LNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGL 100 L E+++ + A FA+ + P + + +E ++ Q G GV + D G + Sbjct: 19 LTEDERMIRDSAKAFASDVLLPRVEKAYLEETTDPELFHLMGQAGLLGVTLPEDYGAANA 78 Query: 101 SRLDTSVIFEALATGCTSTTAYISIHN-MCAWMIDSFGNEEQRHKFCPPLCTMEKFASYC 159 S + ++ + + + +S+ + + + I ++G++EQR K+ P L + E + Sbjct: 79 SYVAYGLVAREVERIDSGYRSMMSVQSSLVMYPIYAYGSDEQRKKYLPGLVSGELIGCFG 138 Query: 160 LTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGGPGPKGISCIV 219 LTEP +GSD A + T A+K Y L+GSK +IS + +D++VV ++ I + Sbjct: 139 LTEPDAGSDPAGMKTRAEKIDGGYRLSGSKMWISNSPIADVFVVWAKSAAH-DNAIRGFI 197 Query: 220 VEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGGRIN 279 +EKG GLS K K+ + T ++ + V + G LN R Sbjct: 198 LEKGMKGLSAPKIGGKLSLRASITGEIVMDGVEVSEDAIL-PNVSGLKGPFGCLNRARYG 256 Query: 280 IASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNAAVA 339 I+ LGAA R + RKQF +PLA Q Q LADM T + Sbjct: 257 ISWGVLGAAEDCWFRARQYGLDRKQFNKPLAGTQLYQKKLADMQTEIALGIQASLRVG-R 315 Query: 340 LQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQILEG 399 L +E K A + S+ K + I QA MHGG G +Y V ++ ++ EG Sbjct: 316 LFDEGKMAPEMISIVKRNNCGKALDIARQARDMHGGNGIQIEYHVMRHAQNLETVNTYEG 375 Query: 400 SNEVMRILISRS 411 +++V +++ R+ Sbjct: 376 THDVHALILGRA 387 >1SIR-A nrPDB Length = 394 Score = 374 bits (961), Expect = e-104, Method: Composition-based stats. Identities = 100/376 (26%), Positives = 174/376 (46%), Gaps = 11/376 (2%) Query: 41 LNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGL 100 L ++ + + + P + ++ E+F +++ + +LG G I+ G +G+ Sbjct: 16 LTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTIK-GYGCAGV 74 Query: 101 SRLDTSVIFEALATGCTSTTAYISIHN-MCAWMIDSFGNEEQRHKFCPPLCTMEKFASYC 159 S + ++ L + + +S+ + + I ++G+EEQR K+ P L E + Sbjct: 75 SSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFG 134 Query: 160 LTEPGSGSDAASLLTSAKKQGD--HYILNGSKAFISGAGESDIYVVMCRTGGPGPKGISC 217 LTEP SGSD +S+ T A Y LNG+K +I+ + +D++VV R +G Sbjct: 135 LTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDGCIRG--- 191 Query: 218 IVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRI-GSEGQGFLIAVRGLNGG 276 ++EKG GLS + + K + T +I + VP N + G+ G LN Sbjct: 192 FLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASSLGG--PFGCLNNA 249 Query: 277 RINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNA 336 R IA LGA+ + R + R QFG PLA NQ +Q LADM T + Sbjct: 250 RYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLTEITLGLHACLQL 309 Query: 337 AVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQI 396 L+++ K A + S+ K + I QA M GG G +Y V ++ + Sbjct: 310 G-RLKDQDKAAPEMVSLLKRNNCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNT 368 Query: 397 LEGSNEVMRILISRSL 412 EG++++ +++ R++ Sbjct: 369 YEGTHDIHALILGRAI 384 >3SWO-A nrPDB Length = 399 Score = 373 bits (959), Expect = e-104, Method: Composition-based stats. Identities = 88/378 (23%), Positives = 175/378 (46%), Gaps = 8/378 (2%) Query: 36 DPSMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDV 95 D L++++++ F + PN+ W + P ++ ++ LG G+++ Sbjct: 21 DTDRLLDQDERDIAATVRQFVDTRLKPNVEGWFESATLPSELAKEFGNLGVLGMHL-QGY 79 Query: 96 GGSGLSRLDTSVIFEALATGCTSTTAYISIH-NMCAWMIDSFGNEEQRHKFCPPLCTMEK 154 G +G + + + L G + +++S+ ++ + I +G+EEQ++++ P L + Sbjct: 80 GCAGTNAVSYGLACMELEAGDSGFRSFVSVQGSLSMFSIYRYGSEEQKNEWLPRLAAGDA 139 Query: 155 FASYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGGPGPKG 214 + LTEP GS+ A + T A++ G +ILNG+K +I+ +D+ V +T G Sbjct: 140 IGCFGLTEPDFGSNPAGMRTRARRDGSDWILNGTKMWITNGNLADVATVWAQTDD----G 195 Query: 215 ISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLN 274 I +V TPG + + +K+ + T ++ ++ +P + ++ +G + LN Sbjct: 196 IRGFLVPTDTPGFTANEIHRKLSLRASVTSELVLDNVRLPASAQL-PLAEGLSAPLSCLN 254 Query: 275 GGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVR 334 R I +LGAA S+ T + R+ F +PL++ Q Q LA+M L L+ Sbjct: 255 EARFGIVFGALGAARDSLETTIAYTQSREVFDKPLSNYQLTQEKLANMTVELGKGMLLAI 314 Query: 335 NAAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVH 394 + E S+ KL E AI + + GG G +Y+ ++ + Sbjct: 315 HLGRIKDAEGVR-PEQISLGKLNNVREAIAIARECRTLLGGSGITLEYSPLRHANNLESV 373 Query: 395 QILEGSNEVMRILISRSL 412 EG++E+ + I ++L Sbjct: 374 LTYEGTSEMHLLSIGKAL 391 >5ZW7-A nrPDB Length = 402 Score = 368 bits (946), Expect = e-102, Method: Composition-based stats. Identities = 103/379 (27%), Positives = 186/379 (49%), Gaps = 5/379 (1%) Query: 38 SMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGG 97 L+ Q + + A+ FA + + +++ ++ +KAA GF + GG Sbjct: 2 DFNLSNSQSDIYESAYRFACDVLDQDAQTRISQKILSTELWKKAAAYGFAHGPVSHQFGG 61 Query: 98 SGLSRLDTSVIFEALATGCTSTTAYISI--HN-MCAWMIDSFGNEEQRHKFCPPLCTMEK 154 S L LDT+++ EAL G S+ H C + FG+ E + K+ L T + Sbjct: 62 SELGALDTALMIEALGKGSRDIGLSFSLCAHLCACVIPLYRFGSSELKDKYLESLVTGKL 121 Query: 155 FASYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTG-GPGPK 213 A+ TEP +GSD ++ +A+ YILNG K FI+ A +D++++ +T G Sbjct: 122 IAANAATEPDAGSDIYNMQATAQPCEGGYILNGKKIFITNAPIADVFIIYAKTNPDHGFL 181 Query: 214 GISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGL 273 G+S ++EKGTPGL+ G+ K ++ P ++F D +P + RIG EG G I + Sbjct: 182 GVSAFLIEKGTPGLNVGEVIPKDCLSNCPWSEIVFNDIFIPQSQRIGMEGAGGAIFHDSM 241 Query: 274 NGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMV 333 + +++ +G + T ++ R+QFG+ + Q + + DM RL RLM+ Sbjct: 242 IWEKGCLSALFVGGLARLLETTLEYAKARQQFGKAIGQFQSVSNRIIDMKLRLEQCRLML 301 Query: 334 RNAAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRV 393 A ++ +DA A +M+KL ++ A+Q GG ++ + +++ + Sbjct: 302 YRACWK-HDQGQDAEADIAMSKLLISEYAVQSGLDAIQTFGGAAMDQELGLVRHLLNMIP 360 Query: 394 HQILEGSNEVMRILISRSL 412 +I G+N++ + +I+R L Sbjct: 361 SRIFSGTNDIQKEIIARKL 379 >3P4T-A nrPDB Length = 403 Score = 368 bits (944), Expect = e-102, Method: Composition-based stats. Identities = 129/377 (34%), Positives = 191/377 (50%), Gaps = 2/377 (0%) Query: 38 SMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGG 97 S+ E++ +K FA RE+ P+ EW++ P ++ RKAA+LG G D GG Sbjct: 23 SIWTTAEREALRKTVRAFAEREVLPHAHEWERAGEIPRELHRKAAELGLLGAGFPEDAGG 82 Query: 98 SGLSRLDTSVIFEALATGCTSTTAYISIHN--MCAWMIDSFGNEEQRHKFCPPLCTMEKF 155 SG D VI E + + Y S+ + + + G++ + P EK Sbjct: 83 SGGDGADPVVICEEMHYAGSPGGVYASLFTCGIAVPHMIASGDQRLIDTYVRPTLRGEKI 142 Query: 156 ASYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGGPGPKGI 215 + +TEPG GSD L T A GDHY++NG+K +I+ +D V RTGGPG G+ Sbjct: 143 GALAITEPGGGSDVGHLRTRADLDGDHYVINGAKTYITSGVRADYVVTAARTGGPGAGGV 202 Query: 216 SCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNG 275 S IVV+KGTPG +K K+GW S T + + D VPVAN +GSE GF Sbjct: 203 SLIVVDKGTPGFEVTRKLDKMGWRSSDTAELSYTDVRVPVANLVGSENTGFAQIAAAFVA 262 Query: 276 GRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRN 335 R+ +A+ + A + LT + R FG PL S Q +Q TLA MA R+ AR+ R+ Sbjct: 263 ERVGLATQAYAGAQRCLDLTVEWCRNRDTFGRPLISRQAVQNTLAGMARRIDVARVYTRH 322 Query: 336 AAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQ 395 + +A AK A + + NQA+Q+ GG GY+ + V++ RD R+ Sbjct: 323 VVERQLAGETNLIAEVCFAKNTAVEAGEWVANQAVQLFGGMGYMAESEVERQYRDMRILG 382 Query: 396 ILEGSNEVMRILISRSL 412 I G+ E++ L +++L Sbjct: 383 IGGGTTEILTSLAAKTL 399 >6ES9-A nrPDB Length = 551 Score = 365 bits (936), Expect = e-101, Method: Composition-based stats. Identities = 110/390 (28%), Positives = 194/390 (49%), Gaps = 15/390 (3%) Query: 38 SMGLNEEQKEFQKVAFDFAAREMAPNMAEWD-QKELFPVDVMRKAAQLGFGGVYIQTDVG 96 + GL+E+ + + +A + PN EW + +L P++++ + A+LG G+ I + G Sbjct: 164 ATGLDEDLEMIRDQFRRYAEERVIPNAHEWHLKDQLIPMEIIEELAELGVFGLTIPEEFG 223 Query: 97 GSGLSRLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSFGNEEQRHKFCPPLCTMEKFA 156 G GLS+ V+ E L+ G + + + A +I G E Q+ K+ P L + E + Sbjct: 224 GLGLSKASMVVVTEELSRGYIGVGSLGTRSEIAAELILCGGTEAQKAKWLPGLASGEILS 283 Query: 157 SYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGGPGP--KG 214 + TEP +GSD SL T A + G+ +++ G+K +I+ A + + ++ RT +G Sbjct: 284 TAVFTEPNTGSDLGSLRTRAVRDGEDWVVTGNKTWITHAQRTHVMTLLARTDPETTDWRG 343 Query: 215 ISCIVVEK---------GTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSE-GQ 264 +S + EK TPG++ G+ E +G+ + F+ + N +G E G+ Sbjct: 344 LSMFLAEKEPGTDDDPFPTPGMTGGEIE-VLGYRGMKEYELGFDGFRIKGENLLGGEPGR 402 Query: 265 GFLIAVRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMAT 324 GF + RI A+ ++G A ++ + + RKQFG+ L + LA MA Sbjct: 403 GFKQLMETFESARIQTAARAVGVAQSAAEIGMRYAVDRKQFGKSLIEFPRVADKLAMMAV 462 Query: 325 RLVAARLMVRNAAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAV 384 ++ AR + +A R+ MAKL +A + ALQ+HGG G+ +YA+ Sbjct: 463 EIMIARQLTYFSAWEKDHGRR-CDLEAGMAKLLGARVAWAAADNALQIHGGNGFALEYAI 521 Query: 385 QQYVRDSRVHQILEGSNEVMRILISRSLLQ 414 + + D+R+ I EG+ E+ +I+R LL Sbjct: 522 SRVLCDARILNIFEGAAEIQAQVIARRLLD 551 >2IX5-A nrPDB Length = 436 Score = 363 bits (932), Expect = e-101, Method: Composition-based stats. Identities = 96/373 (25%), Positives = 166/373 (44%), Gaps = 6/373 (1%) Query: 41 LNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGL 100 L E++ +K + +E+AP M E+ +K FP + K +G G I+ G GL Sbjct: 55 LTPEEQAIRKKVRECMEKEVAPIMTEYWEKAEFPFHITPKLGAMGVAGGSIK-GYGCPGL 113 Query: 101 SRLDTSVIFEALATGCTSTTAYISIHN-MCAWMIDSFGNEEQRHKFCPPLCTMEKFASYC 159 S ++ +A S + +I +H+ + I G+E Q+ K+ P L + A + Sbjct: 114 SITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNTVACWA 173 Query: 160 LTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGGPGPKGISCIV 219 LTEP +GSDA+ L T+A K + +NG K +I + +D+ ++ R I+ + Sbjct: 174 LTEPDNGSDASGLGTTATKVEGGWKINGQKRWIGNSTFADLLIIFAR--NTTTNQINGFI 231 Query: 220 VEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGGRIN 279 V+K PGL K K+G ++ ++ VP +R+ F + L R+ Sbjct: 232 VKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNS-FQDTSKVLAVSRVM 290 Query: 280 IASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNAAVA 339 +A +G + + +L RKQFG PLA+ Q Q L M + A LM Sbjct: 291 VAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNVQAMFLMGWRLC-K 349 Query: 340 LQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQILEG 399 L E + S+ K + + + + ++ GG G L D+ V + D EG Sbjct: 350 LYETGQMTPGQASLGKAWISSKARETASLGRELLGGNGILADFLVAKAFCDLEPIYTYEG 409 Query: 400 SNEVMRILISRSL 412 + ++ ++ R + Sbjct: 410 TYDINTLVTGREV 422 >6CY8-B nrPDB Length = 380 Score = 361 bits (928), Expect = e-100, Method: Composition-based stats. Identities = 111/381 (29%), Positives = 180/381 (47%), Gaps = 11/381 (2%) Query: 38 SMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVG- 96 + EQ E + A F AP + FP D G+ G+ I Sbjct: 2 NFEWTHEQAELFEHALRFGKELSAPL----QEDNGFPRDNWNALGDFGYFGLPIPEKYAK 57 Query: 97 -GSGLSRLDTSVIFEALATGCTSTTAYIS--IHNM-CAWMIDSFGNEEQRHKFCPPLCTM 152 GSG L T I E L CT T + H C+ I G+E +H+ P L T Sbjct: 58 DGSGFDILTTIKIIEGLGQSCTDTGLLFAGAAHTFACSMPILEHGSETLKHQLLPDLATG 117 Query: 153 EKFASYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGG-PG 211 K A+ ++E +GSD ++L T+A+K+GD+Y+LNG K++++ +D YVV T G Sbjct: 118 RKIAANAISEASAGSDISNLATTAQKEGDYYVLNGGKSYVTNGSIADYYVVYATTNKKHG 177 Query: 212 PKGISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVR 271 G + VV + TPG+S G K+G S P V F++C + +G EGQG I Sbjct: 178 YLGQTAFVVPRNTPGISVGNDYHKLGLRSAPLNQVFFDNCTIHKDYALGREGQGARIFAA 237 Query: 272 GLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARL 331 ++ R + + +GA + ++ N R Q + ++ Q + +ADM RL +ARL Sbjct: 238 SMDWERCCLFAIFVGAMQRDLNQCIEYANTRMQGDKTISRFQAVSHRIADMGVRLESARL 297 Query: 332 MVRNAAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDS 391 M+ AA ++ + A +M+KL ++ ++++HG GYL + V ++D+ Sbjct: 298 MLYYAAWQKSQDVDNTKA-VAMSKLAISEAFVQSGIDSIRVHGALGYLDEGRVNNSIKDA 356 Query: 392 RVHQILEGSNEVMRILISRSL 412 + G++++ R LI L Sbjct: 357 LGSVLFSGTSDIQRELICNRL 377 >5AHS-A nrPDB Length = 401 Score = 344 bits (882), Expect = 5e-95, Method: Composition-based stats. Identities = 122/383 (31%), Positives = 194/383 (50%), Gaps = 11/383 (2%) Query: 40 GLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSG 99 L EQ+ Q A + A A + D E +P D + + GF G+ + T VGG G Sbjct: 3 ELTPEQRTLQTQARELAQSVFASTAVQTDLTEQYPWDNVAQLRDAGFMGMMLPTSVGGRG 62 Query: 100 LSRLDTSVIFEALATGCTSTTAYISIHNMCA-WMIDSFGNEEQRHKFCPPLCTMEKFASY 158 LS LDT ++ E +A C + N+ A I +G+EEQ K L + Sbjct: 63 LSTLDTVIVIEEMAKACATMGRITVDSNLGAIGAITKYGSEEQI-KLAADLVLAGDKPAI 121 Query: 159 CLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGGPG-PKGISC 217 C++EP +GS A+ + T A K GDHYILNG K +I+G G S ++++ R G +GI Sbjct: 122 CISEPNAGSAASEMTTRADKNGDHYILNGEKYWITGGGVSKLHLIFARVFDDGVEQGIGA 181 Query: 218 IVV---EKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIG-SEG--QGFLIAVR 271 + + G GL G++ +G P + F D + + I +G +GF + Sbjct: 182 FITVLDDHGPEGLKVGRRLYAMGVRGIPETHLEFHDLKIHKSMMITFPDGLKRGFAALMS 241 Query: 272 GLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARL 331 N R+ + +LG A + +L R+QFG PLA Q LQ+ +ADM+ +L AARL Sbjct: 242 AYNAQRVGAGAVALGIAQCAFEEGVAYLKRREQFGRPLAEFQGLQWMVADMSVQLEAARL 301 Query: 332 MVRNAAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDS 391 M+R+AAV+ + + + AK+FA + + N ALQ G GY + ++++VRD+ Sbjct: 302 MLRSAAVSGET--FPDINKAAQAKIFAAETANKVTNDALQFFGSSGYGRHNPMERHVRDA 359 Query: 392 RVHQILEGSNEVMRILISRSLLQ 414 R+ I G+ +++R ++ +L Sbjct: 360 RMFTIAGGTAQILRTQVASKILD 382 >5IDU-A nrPDB Length = 410 Score = 339 bits (871), Expect = 9e-94, Method: Composition-based stats. Identities = 106/374 (28%), Positives = 188/374 (50%), Gaps = 9/374 (2%) Query: 45 QKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQ-TDVGGSG--LS 101 +E +A + +A + D + ++R + G+ + GG G + Sbjct: 30 HRELAAGIEAWATQHLA--CVQHDDTDTTCRKLVRALGEAGWLKYGVGGAQYGGHGDTID 87 Query: 102 RLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSFGNEEQRHKFCPPLCTMEKFASYCLT 161 ++ E LA +++ + + I G EQ+ ++ P + E A++ L+ Sbjct: 88 TRAVCLLRETLANHDGLADFALAMQGLGSGAITLAGTHEQKIRYLPRVSKGEAIAAFALS 147 Query: 162 EPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTG-GPGPKGISCIVV 220 EP +GSD A++ A+ +GD Y+++G K +IS G +D YVV RTG PG +GIS +V Sbjct: 148 EPDAGSDVAAMSLQARAEGDCYVIDGDKTWISNGGIADFYVVFARTGEAPGARGISAFIV 207 Query: 221 EKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGGRINI 280 + TPGL ++ + P + F+ VP + +G+ G+GF IA+R L+ R ++ Sbjct: 208 DADTPGLQIAERIDVIA--PHPLARLHFDSARVPRSQMLGAPGEGFKIAMRTLDVFRTSV 265 Query: 281 ASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNAAVAL 340 A+ SLG A ++ RK FG+ L Q Q LA MA + ++ L+V AA L Sbjct: 266 AAASLGFARRALQEGLARAASRKMFGQTLGDFQLTQTKLAQMALTIDSSALLVYRAAW-L 324 Query: 341 QEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQILEGS 400 +++ ++ +MAK A++ + + A+Q+ GG G V++ R+ R +I EG+ Sbjct: 325 RDQGENVTREAAMAKWHASEGAQQVIDAAVQLWGGMGVQSGTTVERLYREIRALRIYEGA 384 Query: 401 NEVMRILISRSLLQ 414 EV ++++ R LL+ Sbjct: 385 TEVQQLIVGRDLLK 398 >5JSC-A nrPDB Length = 410 Score = 318 bits (814), Expect = 4e-87, Method: Composition-based stats. Identities = 104/354 (29%), Positives = 181/354 (51%), Gaps = 7/354 (1%) Query: 65 AEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGLSRLDT---SVIFEALATGCTSTTA 121 + + + ++R+ G+ + G +DT ++ E LA Sbjct: 48 EDHEDVDATCRRLVRELGAAGWLKYGVGGVAYGGHGDTIDTRAVCLLRETLAKHSGLADF 107 Query: 122 YISIHNMCAWMIDSFGNEEQRHKFCPPLCTMEKFASYCLTEPGSGSDAASLLTSAKKQGD 181 +++ + + I G EQ+ ++ P + A++ L+EP +GSD A++ SA++ GD Sbjct: 108 ALAMQGLGSGAISLGGTHEQKTRYLPRVANGTAIAAFALSEPEAGSDVAAMTLSAREDGD 167 Query: 182 HYILNGSKAFISGAGESDIYVVMCRTG-GPGPKGISCIVVEKGTPGLSFGKKEKKVGWNS 240 Y+L+G K +IS G +D YVV RTG PG +GIS VV+ TPGL ++ + Sbjct: 168 AYVLDGDKTWISNGGIADFYVVFARTGEAPGARGISAFVVDADTPGLEIAERIDVIA--P 225 Query: 241 QPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGGRINIASCSLGAAHASVILTRDHLN 300 P + F VP + +G+ G+GF +A+R L+ R ++A+ SLG A ++ Sbjct: 226 HPLARLHFAGARVPRSQMLGAPGEGFKLAMRTLDIFRTSVAAASLGFARHAMAEGVARAA 285 Query: 301 VRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNAAVALQEERKDAVALCSMAKLFATD 360 RK FG+ L Q Q LA MA + ++ L+V AA L+++ ++ +MAK A++ Sbjct: 286 SRKMFGQTLGDFQLTQAKLAQMALTIDSSALLVYRAAW-LRDQGENVTREAAMAKWHASE 344 Query: 361 ECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQILEGSNEVMRILISRSLLQ 414 + + A+Q++GG G AV+ R+ R +I EG+ EV ++++ R LL+ Sbjct: 345 GAQQVIDAAVQLYGGMGVQSGTAVEMLYREIRALRIYEGATEVQQLIVGRDLLK 398 >4RM7-A nrPDB Length = 391 Score = 299 bits (765), Expect = 2e-81, Method: Composition-based stats. Identities = 81/380 (21%), Positives = 173/380 (45%), Gaps = 7/380 (1%) Query: 40 GLNEEQKEFQKVAFDFAAREMAP-NMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGS 98 GL+ +++ ++ + P ++++W + + P +V++ L F G + Sbjct: 7 GLSRDEQRLLNHVREYGEKYFTPASISKWRKDQGLPDEVVKAFVDLDFNGFGVIHRRNHR 66 Query: 99 GLSRLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSFGNEEQRHKFCPPLCTMEKFA-S 157 ++ E L+ + + + + ++++F + Q F + + + Sbjct: 67 TYDLFAQVLVIEELSRISGACLPFQND-LLQLQILEAFASSAQTSPFRTEYQDTGRLSYA 125 Query: 158 YCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMC--RTGGPGPKGI 215 ++EP +GSD S+ T ++GD ++NG+K F++ + +V +TG G Sbjct: 126 LAISEPEAGSDTRSMRTHVTREGDTLVMNGTKMFVNNGEYAPALLVSAYDKTGDDGEPEF 185 Query: 216 SCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNG 275 S +V + G+ + E+K+G + P V F++ V + R+ +GF L Sbjct: 186 SFWMVPRSAAGI-YAYPEQKIGQSMLPFATVRFDNVEVKESWRLKGSSKGFSQLYSLLEY 244 Query: 276 GRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRN 335 GR+ + +LG A A++ R+ FG+ +A Q +Q L +M +L R +V Sbjct: 245 GRVFTCAAALGEAQAAMEDAVAWARGREAFGQRIADLQQVQMKLTEMEVKLTNMRNLVYG 304 Query: 336 AAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQ 395 AA +++ M K + + + A+Q+ GG GY+++ V +D R +Q Sbjct: 305 AAREYDRGEHKRLSVALM-KYYVPKAATEVASDAMQILGGRGYIQENRVSSIWQDCRGYQ 363 Query: 396 ILEGSNEVMRILISRSLLQE 415 +G++EVM ++ + +L++ Sbjct: 364 FADGTDEVMVVIAAPLILEQ 383 >2WBI-A nrPDB Length = 428 Score = 290 bits (743), Expect = 7e-79, Method: Composition-based stats. Identities = 96/423 (22%), Positives = 181/423 (42%), Gaps = 35/423 (8%) Query: 23 LVQTGHRSLTSCIDPSMGL---NEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVD--- 76 + + ++ ID + L + +E F + + P AE + E + + Sbjct: 2 MSKRTFSTVLPQIDTTGQLFVQTRKGQEVLIKVKHFMKQHILP--AEKEVTEFYVQNENS 59 Query: 77 --------VMRKAAQL----GFGGVYIQTDVGGSGLSRLDTSVIFEALATGCTSTTAY-- 122 V+ K ++ G +++ SGLS +D ++I E + + Sbjct: 60 VDKWGKPLVIDKLKEMAKVEGLWNLFLPAV---SGLSHVDYALIAEETGKCFFAPDVFNC 116 Query: 123 ISIHNMCAWMIDSFGNEEQRHKFCPPLCTMEKFASYCLTEPG-SGSDAASLLTSAKKQGD 181 + ++ +G+EEQ+ ++ PL + +C+TEP + SDA ++ S ++ D Sbjct: 117 QAPDTGNMEVLHLYGSEEQKKQWLEPLLQGNITSCFCMTEPDVASSDATNIECSIQRDED 176 Query: 182 HYILNGSKAFISGA--GESDIYVVMCRTGGPG---PKGISCIVVEKGTPGLSFGKKEKKV 236 Y++NG K + SGA + I +V+ RT K S I+V TPG+ + Sbjct: 177 SYVINGKKWWSSGAGNPKCKIAIVLGRTQNTSLSRHKQHSMILVPMNTPGVKIIRPLSVF 236 Query: 237 GWNSQ---PTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGGRINIASCSLGAAHASVI 293 G+ + F VP N I EG+GF I+ L GRI+ ++G A ++ Sbjct: 237 GYTDNFHGGHFEIHFNQVRVPATNLILGEGRGFEISQGRLGPGRIHHCMRTVGLAERALQ 296 Query: 294 LTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNAAVALQE-ERKDAVALCS 352 + + R F + L +++ + +A+ + RL+ AA ++ A + Sbjct: 297 IMCERATQRIAFKKKLYAHEVVAHWIAESRIAIEKIRLLTLKAAHSMDTLGSAGAKKEIA 356 Query: 353 MAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQILEGSNEVMRILISRSL 412 M K+ A I + A+Q+ GG G +DY + +RV ++ +G +EV I+ Sbjct: 357 MIKVAAPRAVSKIVDWAIQVCGGAGVSQDYPLANMYAITRVLRLADGPDEVHLSAIATME 416 Query: 413 LQE 415 L++ Sbjct: 417 LRD 419 >4HR3-A nrPDB Length = 415 Score = 285 bits (729), Expect = 3e-77, Method: Composition-based stats. Identities = 91/397 (22%), Positives = 177/397 (44%), Gaps = 28/397 (7%) Query: 47 EFQKVAFDFAAREMAPN----MAEWDQ----KELFPVDVMR----------KAAQLGFGG 88 E +F E+ P +A D+ + ++ KA G Sbjct: 15 ELIAAVREFIDAEVMPVERAVLAHHDELLGARAGTTAELWHVPPELDSLKAKARAAGLWN 74 Query: 89 VYIQTDVGGSGLSRLDTSVIFEALATGCTSTTAYI--SIHNMCAWMIDSFGNEEQRHKFC 146 +++ G GLS + + + E + + T + + + ++ +G++EQ+ + Sbjct: 75 LFLPDPELGGGLSNSEYAPLAEQMGRSLFAPTVFNCNAPDSGNMEVLHRYGSQEQKEVWL 134 Query: 147 PPLCTMEKFASYCLTEPG-SGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMC 205 PL + +++C+TEP + SDA ++ +A +GD ++NG K + +G G D V++ Sbjct: 135 EPLLEGDIRSAFCMTEPDVASSDATNMAATAVVEGDEVVINGRKWWSTGVGHPDCKVIIF 194 Query: 206 R--TGGPGPK--GISCIVVEKGTPGLSFGKKEKKVGWNSQPTRA--VIFEDCAVPVANRI 259 T + S ++V TPG++ + +G+ +P V F++ +P I Sbjct: 195 MGLTDPNAHRYARHSMVLVPMDTPGITVERMLPTMGFYDEPGGHGVVSFDNVRLPADAFI 254 Query: 260 GSEGQGFLIAVRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTL 319 G+GF IA L GR++ A +G A ++ R FG+PL + + + Sbjct: 255 AGPGKGFEIAQGRLGPGRVHHAMRLIGLAEVALEHACRRGLDRTAFGKPLVNLGGNRERI 314 Query: 320 ADMATRLVAARLMVRNAAVALQE-ERKDAVALCSMAKLFATDECFAICNQALQMHGGYGY 378 AD + RL+V +AA L A++ S K+ A + + + A+Q+HGG G Sbjct: 315 ADARIAINQTRLLVLHAAWLLDTVGIMGALSAVSEIKVAAPNMAQQVIDMAIQIHGGGGL 374 Query: 379 LKDYAVQQYVRDSRVHQILEGSNEVMRILISRSLLQE 415 D+ + ++R ++ +G +EV R +++R L + Sbjct: 375 SNDFPLAAAWVNARALRLADGPDEVHRGVVARIELAK 411 >1R2J-A nrPDB Length = 366 Score = 276 bits (706), Expect = 1e-74, Method: Composition-based stats. Identities = 85/352 (24%), Positives = 153/352 (43%), Gaps = 5/352 (1%) Query: 63 NMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGLSRLDTSVIFEALATGCTSTTAY 122 AEWD P D++ + G + + GG GL + + + C+S + Sbjct: 15 RAAEWDTSGELPRDLLVRLGADGLLCAEVAAEHGGLGLGSRENGEFTAHVGSLCSSLRSV 74 Query: 123 ISIHNMCAWMIDSFGNEEQRHKFCPPLCTMEKFASYCLTEPGSGSDAASLLTSAKKQGDH 182 ++ M AW + G+ QR F L + K A+ +E +GSD +++ T + GD Sbjct: 75 MTSQGMAAWTVQRLGDAGQRATFLKELTSG-KLAAVGFSERQAGSDLSAMRTRVRLDGDT 133 Query: 183 YILNGSKAFISGAGESDIYVVMCRTGGPGPKGISCIVVEKGTPGLSFGKKEKKVGWNSQP 242 +++G K + + A +D VV G + +VV TPG+ + K G + Sbjct: 134 AVVDGHKVWTTAAAYADHLVVF---GLQEDGSGAVVVVPADTPGVRVERVPKPSGCRAAG 190 Query: 243 TRAVIFEDCAVPVANRIGSEGQGF-LIAVRGLNGGRINIASCSLGAAHASVILTRDHLNV 301 + + VP + G ++ L GR ++A +G A H Sbjct: 191 HADLHLDQVRVPAGAVLAGSGASLPMLVAASLAYGRKSVAWGCVGILRACRTAAVAHART 250 Query: 302 RKQFGEPLASNQYLQFTLADMATRLVAARLMVRNAAVALQEERKDAVALCSMAKLFATDE 361 R+QFG PL +Q + +AD+ T A + A+ E + V +AK A + Sbjct: 251 REQFGRPLGDHQLVAGHIADLWTAEQIAARVCEYASDHWDEGSPEMVPATILAKHVAAER 310 Query: 362 CFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQILEGSNEVMRILISRSLL 413 A A Q+ G + + V++ RD+++ +I+EGS+E+ R+++++ L Sbjct: 311 AAAGAATAAQVLASAGAREGHVVERAYRDAKLMEIIEGSSEMCRVMLAQHAL 362 >4X28-A nrPDB Length = 400 Score = 270 bits (691), Expect = 8e-73, Method: Composition-based stats. Identities = 91/391 (23%), Positives = 164/391 (41%), Gaps = 30/391 (7%) Query: 42 NEEQKEFQKVAFDFAAREMAPNMAEWDQK-------ELFPVDVMRKAAQLGFGGVYIQTD 94 +Q+E ++ + A M P E + + + + G+ + + Sbjct: 6 TPQQEELRRELRSYFATLMTPERREALSSVQGEYGVGNVYRETIAQMGRDGWLALGWPKE 65 Query: 95 VGGSGLSRLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSFGNEEQRHKFCPPLCTMEK 154 GG G S +D + + A + +++I N A I ++G +EQ+ F P + + Sbjct: 66 YGGQGRSAMDQLIFTDE-AAIAGAPVPFLTI-NSVAPTIMAYGTDEQKRFFLPRIAAGDL 123 Query: 155 FASYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRT-----GG 209 S +EPG+G+D A+L T+A + GD Y++NG K + S +D + RT G Sbjct: 124 HFSIGYSEPGAGTDLANLRTTAVRDGDDYVVNGQKMWTSLIQYADYVWLAVRTNPESSGA 183 Query: 210 PGPKGISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIA 269 +GIS ++V G S+ G T A + D VPVANR+G E G+ + Sbjct: 184 KKHRGISVLIVPTTAEGFSWTPVHTMAG---PDTSATYYSDVRVPVANRVGEENAGWKLV 240 Query: 270 VRGLNGGRINIASCSLGAAHASVILTRDHL-NVRKQFGEPLASNQYLQFTLADMATRLVA 328 LN R+ + S + + R+ N + G L ++++Q LA + + Sbjct: 241 TNQLNHERVALVSPA--PIFGCLREVREWAQNTKDAGGTRLIDSEWVQLNLARVHAKAEV 298 Query: 329 ARLMVRNAAVALQ--EERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDY---- 382 +L+ A + ++ + A S AK+F T+ +++ G L+ Sbjct: 299 LKLINWELASSQSGPKDAGPSPADASAAKVFGTELATEAYRLLMEVLGTAATLRQNSPGA 358 Query: 383 ----AVQQYVRDSRVHQILEGSNEVMRILIS 409 V++ R + G+NEV R +I Sbjct: 359 LLRGRVERMHRACLILTFGGGTNEVQRDIIG 389 >5GJ7-A nrPDB Length = 398 Score = 256 bits (654), Expect = 2e-68, Method: Composition-based stats. Identities = 81/367 (22%), Positives = 141/367 (38%), Gaps = 20/367 (5%) Query: 40 GLNEEQKEFQKVAFDFAA--REMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGG 97 L + +E ++ D A E AP E D+ FP + + G+ + + GG Sbjct: 12 ALPADVRERLRITRDLAQAFHERAP---EHDRAGDFPFENIEDLKASGYVRWTVPVEYGG 68 Query: 98 SGLSRLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSFG--NEEQRHKFCPPLCTMEKF 155 GLS + + E LA G ST I H + G +E C + Sbjct: 69 LGLSLEEMLMHQEVLAKGDGSTALAIGWHVGILLHLRETGAFPDELFRMVCESVVKEGAL 128 Query: 156 ASYCLTEPGSGSDAAS--LLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGGPGPK 213 + C TEP +GS + T+A K Y + G K F + + +V Sbjct: 129 INSCATEPATGSPSRGGKPETTAVKVPGGYRITGRKTFSTLSPALTWIMVTATVADEDVV 188 Query: 214 GISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGL 273 G +V K + + +G + + ++ +D VP I + G R Sbjct: 189 GQ--FLVRKED--VEIVETWDTLGMRATGSHDIVLKDVFVPEERVIVIQRPGVQAERRPD 244 Query: 274 NGG-RINIASCSLGAAHASVILTRDHLNVRK--QFGEPLASNQYLQFTLADMATRLVAAR 330 G ++I +C LG A A+ ++ + P+A +++ L +M +L+AAR Sbjct: 245 GSGWLLHIPACYLGIALAARDFALEYAATYRPNTLPHPIAEVPHVEQKLGEMELKLLAAR 304 Query: 331 LMVRNAAVALQ----EERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQ 386 ++ + A EER K AT+ + + A+++ GG + +++ Sbjct: 305 TLLYDLARRFDAASPEERVKLQPQFGAVKTLATNAANQVVDLAMRVVGGRSLSRALPLER 364 Query: 387 YVRDSRV 393 Y RD R Sbjct: 365 YYRDVRA 371 >4ZYJ-A nrPDB Length = 425 Score = 244 bits (624), Expect = 5e-65, Method: Composition-based stats. Identities = 83/412 (20%), Positives = 139/412 (33%), Gaps = 38/412 (9%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLNEEQKEFQKVAFDFAAREMAPNMAE---WDQK 70 G +P G + + H + GL E + + D R + AE D++ Sbjct: 13 GLVPRGSHMTKPSVHEH--PGVLADNGLCEPKTPAGRRLLDLLERYLPALEAESRDNDRE 70 Query: 71 ELFPVDVMRKAAQLGFGGVYIQTDVGGSGLSRLDTSVIFEALATGCTSTTAYISIHNMCA 130 PV + + + G G + D+GG G+ L + A G + A Sbjct: 71 ATLPVHLFDRMRKEGVLGATVPEDLGGLGVHSLHDVALALARIAGRDAGVALALHMQFSR 130 Query: 131 WMIDSF-------GNEEQRHKFCPPLCTMEKFASYCLTEPGSGSDAASLLTSAKKQGDHY 183 + F + E G+ D + Y Sbjct: 131 GLTLDFEWRHGAPSTRPLAEDLLRQMGAGEAVIC------GAVKDVRGTTVLTRATDGSY 184 Query: 184 ILNGSKAFISGAGESDIYVVMCRTGGPG-PKGISCIVVEKGTPGLSFGKKEKKVGWNSQP 242 LNG K +S AG + YVV R G P ++ VV + TPGL+ +G S Sbjct: 185 RLNGRKTLVSMAGIATHYVVSTRLEEAGAPVRLAAPVVARTTPGLTVLDNWDGMGMRSSG 244 Query: 243 TRAVIFEDCAVPVANRI--GSEGQGFLIAVRGLNGGRINIASCSLGAAHASVILTRDHLN 300 + ++F+ C V + G G A+ G I + +G A A+ + Sbjct: 245 SVDIVFDGCPVDRDRVLPRGEPGVRDDAALAGQTVSSIAMLGIYVGIAEAARRIAL--TE 302 Query: 301 VRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNAAVALQE-----------ERKDAVA 349 +R++ G P ++ T+A++ RL A V +A + + Sbjct: 303 LRRRGGAPAG----VRTTVAEIDARLFALHTAVASALTTADRLADDLSGDLAARGRAMMT 358 Query: 350 LCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQILEGSN 401 AKL + + L + GG GY + + + RD R + N Sbjct: 359 PFQYAKLLVNRHSVGVVDDCLMLVGGAGYSNSHPLARLYRDVRAGGFMHPYN 410 >4JEK-A nrPDB Length = 453 Score = 244 bits (623), Expect = 5e-65, Method: Composition-based stats. Identities = 78/420 (18%), Positives = 141/420 (33%), Gaps = 39/420 (9%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLNEEQKEFQ----------KVAFDFAAREMAPN 63 G +P G + TG + + + M L+ E++ + VA A + A Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSEF-MTLSPEKQHVRPRDAADNDPVAVARGLAEKWRA-T 70 Query: 64 MAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGLSRLDTSVIFEALATGCTSTTAYI 123 E D+ G + + + GG G + +A S Sbjct: 71 AVERDRAGGSATAEREDLRASGLLSLLVPREYGGWGADWPTAIEVVREIAAADGSLGHLF 130 Query: 124 SIHNMCAWMIDSFGNEEQRHKFCPPLCTMEKFASYCLTEPGSGSDAASLLTSAKKQGD-H 182 H A MI+ G++EQ + + +E + S SA D Sbjct: 131 GYHLTNAPMIELIGSQEQEEHLYTQIAQNNWWTGNASSE--NNSHVLDWKVSATPTEDGG 188 Query: 183 YILNGSKAFISGAGESDIYVVM--CRTGGPGPKGISCIVVEKGTPGLSFGKKEKKVGWNS 240 Y+LNG+K F SGA SD+ V + P I + G++ +G Sbjct: 189 YVLNGTKHFCSGAKGSDLLFVFGVVQDDSPQQGAIIAAAIPTSRAGVTPNDDWAAIGMRQ 248 Query: 241 QPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGG------RINIASCSLGAAHASVIL 294 + + F + V +G+ L ++ G ++ A+ LG AH ++ Sbjct: 249 TDSGSTDFHNVKVEPDEVLGAPNAFVLAFIQSERGSLFAPIAQLIFANVYLGIAHGALDA 308 Query: 295 TRDHLNVRKQFGEPLASNQYLQF-----TLADMATRLVA----------ARLMVRNAAVA 339 R++ + + P Q + + + L V + A Sbjct: 309 AREYTRTQARPWTPAGIQQATEDPYTIRSYGEFTIALQGADAAAREAAHLLQTVWDKGDA 368 Query: 340 LQ-EERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQILE 398 L E+R + + S K AT+ I + ++ G G Y ++ R+ R H + + Sbjct: 369 LTPEDRGELMVKVSGVKALATNAALNISSGVFEVIGARGTHPRYGFDRFWRNVRTHSLHD 428 >2C12-A nrPDB Length = 439 Score = 240 bits (614), Expect = 5e-64, Method: Composition-based stats. Identities = 86/411 (20%), Positives = 161/411 (39%), Gaps = 47/411 (11%) Query: 38 SMGLNEEQKEFQKVAFDFAAREMAPNMAEW----DQKELFP--VDVMRKAAQLGFGGVYI 91 L+ Q E ++ A FA + AE+ DQ F R+A + G + Sbjct: 3 DFKLSPSQLEARRHAQAFANTVLTKASAEYSTQKDQLSRFQATRPFYREAVRHGLIKAQV 62 Query: 92 QTDVGGSGLSRLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSFGNEEQRHKFCPPLCT 151 +GG+ S + S+I E L +T+ I + + + + KF P + Sbjct: 63 PIPLGGTMESLVHESIILEELFAVEPATSITIVATALGLMPVILCDSPSLQEKFLKPFIS 122 Query: 152 --MEKFASYCLTEPGSGSD-----AASLLTSAKKQGDHYILNGSKAFISGAG-----ESD 199 E AS +EP ++ L T+A+K G+ ++++G K + S +G +D Sbjct: 123 GEGEPLASLMHSEPNGTANWLQKGGPGLQTTARKVGNEWVISGEKLWPSNSGGWDYKGAD 182 Query: 200 IYVVMCRTGGPGPK----------GISCIVVEKGTPGLSFGKK--------EKKVGWNSQ 241 + V+CR K I+ ++V + T ++ KK + G + Sbjct: 183 LACVVCRVSDDPSKPQDPNVDPATQIAVLLVTRET--IANNKKDAYQILGEPELAGHITT 240 Query: 242 PTRAVIFEDCAVPVANRIGSEG---QGFLIAVRGLNGGRINIASCSLGAAHASVILTRDH 298 F + VP N + + G QG + ++ + + ++G A A+ Sbjct: 241 SGPHTRFTEFHVPHENLLCTPGLKAQGLVETAFAMSAALVG--AMAIGTARAAFEEALVF 298 Query: 299 LNVRKQFG-EPLASNQYLQFTLADMATRLVAARLMVRNAAVALQEERKDAVALCSMA--- 354 + G + + +Q + L D RL +RL+V A L++E + MA Sbjct: 299 AKSDTRGGSKHIIEHQSVADKLIDCKIRLETSRLLVWKAVTTLEDEALEWKVKLEMAMQT 358 Query: 355 KLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQILEGSNEVMR 405 K++ TD A++ G Y KD + + + + + + +G N +R Sbjct: 359 KIYTTDVAVECVIDAMKAVGMKSYAKDMSFPRLLNEVMCYPLFDGGNIGLR 409 >3M9V-A nrPDB Length = 439 Score = 240 bits (614), Expect = 6e-64, Method: Composition-based stats. Identities = 79/393 (20%), Positives = 144/393 (36%), Gaps = 28/393 (7%) Query: 32 TSCIDPSMGLNEEQKEFQKVAFDFAAREMA---PNMAEWDQKELFPVDVMRKAAQLGFGG 88 T+ D + GL +V D A + AE D+ FP D + G G Sbjct: 7 TARQDSTTGLYAPVTPAGRVLLDRLAAHLPRIRSTAAEHDRDGTFPTDTFDALRKDGLMG 66 Query: 89 VYIQTDVGGSGLSRLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSF----GNEEQRHK 144 + ++GG G+ RL + ++TA + + + G+E R + Sbjct: 67 ATVPAELGGLGVDRLYDVAVALLAVARADASTALALHMQLSRGLTLGYEWRHGDE--RAR 124 Query: 145 FCPPLCTMEKFASYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVM 204 A + G ++ T ++L+G K +S A +V+ Sbjct: 125 TLAERILRGMVAGDAVVCSGIKDHHTAVTTLRPDGAGGWLLSGRKTLVSMAPVGTHFVIN 184 Query: 205 CRTGG-PGPKGISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIG--S 261 RT G GP ++ VV + TPG + +G + T ++F+DC +P + + Sbjct: 185 ARTDGTDGPPRLASPVVTRDTPGFTVLDNWDGLGMRASGTVDIVFDDCPIPADHVLMRDP 244 Query: 262 EGQGFLIAVRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLAD 321 G + G +++ +G A A+ L R + P A+ L +A+ Sbjct: 245 VGARNDAVLAGQTVSSVSVLGVYVGVAQAAYDTAVAALERRPE--PPQAAALTL---VAE 299 Query: 322 MATRLVAARLMVRNAAVA-----------LQEERKDAVALCSMAKLFATDECFAICNQAL 370 + +RL A R +A A + E + + AKL I + L Sbjct: 300 IDSRLYALRATAGSALTAADALSADLSGDMDERGRQMMRHFQCAKLAVNRLAPEIVSDCL 359 Query: 371 QMHGGYGYLKDYAVQQYVRDSRVHQILEGSNEV 403 + GG Y + + + +RD + + ++ V Sbjct: 360 SLVGGASYTAGHPLARLLRDVQAGRFMQPYAYV 392 >3MXL-A nrPDB Length = 395 Score = 229 bits (584), Expect = 2e-60, Method: Composition-based stats. Identities = 86/387 (22%), Positives = 142/387 (36%), Gaps = 34/387 (8%) Query: 41 LNEEQKEFQKVAFDFAAREMA---PNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGG 97 L + D A + A+ D+ FPV+ + A+LG G + ++GG Sbjct: 5 LRAPLTPAGRTVVDLLAGVIPRISAEAADRDRTGTFPVEAFEQFAKLGLMGATVPAELGG 64 Query: 98 SGLSRL-DTSVIFEALATGCTSTTAYISIHNMCAWMIDSFGNEEQRHKFCPPLCTMEKFA 156 GL+RL D + LA ST + + E +H PP+ M + Sbjct: 65 LGLTRLYDVATALMRLAEADASTALAWHVQLSRGLTL----TYEWQHG-TPPVRAMAERL 119 Query: 157 SYCLTEP-----GSGSDAASLLTSAKKQG-DHYILNGSKAFISGAGESDIYVVMC-RTGG 209 + E G+ DA ++T G ++L+G K +S A + + V R Sbjct: 120 LRAMAEGEAAVCGALKDAPGVVTELHSDGAGGWLLSGRKVLVSMAPIATHFFVHAQRRDD 179 Query: 210 PGPKGISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRI--GSEGQGFL 267 G ++ VV + PGL+ +G + T V+F+ C V + G G Sbjct: 180 DGSVFLAVPVVHRDAPGLTVLDNWDGLGMRASGTLEVVFDRCPVRADELLERGPVGARRD 239 Query: 268 IAVRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLV 327 + G I + G A A+ + R GEP A + L +A + TRL Sbjct: 240 AVLAGQTVSSITMLGIYAGIAQAARDIAVGFCAGR--GGEPRAGARAL---VAGLDTRLY 294 Query: 328 AARLMVRNAAVAL-----------QEERKDAVALCSMAKLFATDECFAICNQALQMHGGY 376 A R V A E + + AK+ + A+ + L + GG Sbjct: 295 ALRTTVGAALTNADAASVDLSGDPDERGRRMMTPFQYAKMTVNELAPAVVDDCLSLVGGL 354 Query: 377 GYLKDYAVQQYVRDSRVHQILEGSNEV 403 Y + + + RD R ++ + V Sbjct: 355 AYTAGHPLSRLYRDVRAGGFMQPYSYV 381 >3MKH-A nrPDB Length = 438 Score = 227 bits (579), Expect = 7e-60, Method: Composition-based stats. Identities = 85/414 (20%), Positives = 145/414 (35%), Gaps = 41/414 (9%) Query: 38 SMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKE-------LFPVDVMRKAAQLGFGGVY 90 L+ QK + A A + P + Q A G Sbjct: 4 DFHLSASQKGTYQAARSLARNLLMPARQTYLQHPPNSPLRFQSTQPTYAAAVSAGILKGQ 63 Query: 91 IQTDVGGSGLSRLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSFGNEEQRHKFCPPLC 150 I GG+G + ++++++ E + S I + I+ Q +F P Sbjct: 64 ISPAHGGTGGTLIESAILVEECYSVEPSAALTIFATGLGLTPINLAAGP-QHAEFLAPFL 122 Query: 151 TME--KFASYCLTEPGSGSDA-----ASLLTSAKKQGDHYILNGSKAFISG-AGE----S 198 + E AS +EPG ++A T+A+ +GD +++NG K + + AG Sbjct: 123 SGEGSPLASLVFSEPGGVANALEKGAPGFQTTARLEGDEWVINGEKMWATNCAGWDFKGC 182 Query: 199 DIYVVMCRT-------GGPGPKGISCIVVEK------GTPGLSFGKKEKKVGWNSQPTRA 245 D+ V+CR G + I+V + G + G S Sbjct: 183 DLACVVCRDATTPLEEGQDPENKVMIILVTRADLDRNGEGSFEVLRHVATPGHTSVSGPH 242 Query: 246 VIFEDCAVPVANRIGSEGQGFLIAVRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQF 305 V + + VP N + GQG +A +G + + + +G A+ + Sbjct: 243 VRYTNVRVPTKNVLCPAGQGAKVAFGAFDGSAVLVGAMGVGLMRAAFDAALKFAKEDNRG 302 Query: 306 GE-PLASNQYLQFTLADMATRLVAARLMVRNAAVALQEERKDAVA---LCSMAKLFATDE 361 G PL Q L+ + + AAR + AA A++ D A L AK+F ++ Sbjct: 303 GAVPLLERQAFADLLSGVKIQTEAARALTWKAAHAMENGPGDYDARRELALAAKVFCSEA 362 Query: 362 CFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQILEGSNEVMRILISRSLLQE 415 C + G Y + + V I +G N + I R LQ+ Sbjct: 363 AVKACTDVINAVGISAYDLQRPFSDLLNTAVVLPIFDGGN----VGIRRRHLQQ 412 >5YS9-A nrPDB Length = 708 Score = 217 bits (552), Expect = 9e-57, Method: Composition-based stats. Identities = 84/431 (19%), Positives = 152/431 (35%), Gaps = 68/431 (15%) Query: 43 EEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGLSR 102 E +++ + + ++D P + +R+ A + G Sbjct: 50 ENVTMIERLMTELERDPVLNVSGDYD----MPKEQLRETAVARIAALS-----GHWKKDT 100 Query: 103 LDTSVIFEAL-ATGCTSTTAYISIH-NMCAWMIDSFGNEEQRHKFCPPLCT--MEKFASY 158 +++ L T + +H + I G +EQ + + + Sbjct: 101 EKEALLRSQLHGIVDMGTRIRLGVHTGLFMGAIRGSGTKEQYDYWVRKGAADVKGFYGCF 160 Query: 159 CLTEPGSGSDAASLLTSAK--KQGDHYILN-----GSKAFISGAGESDIYVV-MCRTGGP 210 +TE G GS+ A L T+A + D +I+N +K +I GA S + R Sbjct: 161 AMTELGHGSNVAGLETTATYIQDTDEFIINTPNTGATKWWIGGAAHSATHTACFARLLVD 220 Query: 211 GPK-GISCIVVE-KG------TPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRI--- 259 G G+ VV+ + PG++ G KK+G ++ + F + +P N + Sbjct: 221 GKDYGVKIFVVQLRDVSSHSLMPGIALGDIGKKMGRDAIDNGWIQFTNVRIPRQNMLMKY 280 Query: 260 ------GSEGQG--FLIAVRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFG----E 307 G Q + L GGR+ + + S + + + + VR+QFG + Sbjct: 281 AKVSSTGKVSQPPLAQLTYGALIGGRVTMIADSFFVSQRFITIALRYACVRRQFGTTPGQ 340 Query: 308 P---LASNQYLQFTLADMATRLVAARLMVRNAAVALQE---------------------E 343 P + Y Q L + A ++ + + + + Sbjct: 341 PETKIIDYPYHQRRLLPLLAFTYAMKMAADQSQIQYDQTTDLLQTIDPKDKGALGKAIVD 400 Query: 344 RKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQILEGSNEV 403 K+ A + K F T C I +Q Q GG+GY Q D V EG N V Sbjct: 401 LKELFASSAGLKAFTTWTCANIIDQCRQACGGHGYSGYNGFGQAYADWVVQCTWEGDNNV 460 Query: 404 MRILISRSLLQ 414 + + + R L+Q Sbjct: 461 LCLSMGRGLIQ 471 >4X28-D nrPDB Length = 373 Score = 217 bits (552), Expect = 1e-56, Method: Composition-based stats. Identities = 76/385 (19%), Positives = 139/385 (36%), Gaps = 28/385 (7%) Query: 38 SMGLNEEQKEFQKVAFDFAAREMAP-NMAEWDQ-KELFPVDVMRKAAQLGFGGVYIQTDV 95 E ++ + P + E D+ ++ F ++ RK G + Sbjct: 2 DFTTTEAAQDLGGLVDTIVDAVCTPEHQRELDKLEQRFDRELWRKLIDAGILSSAAPESL 61 Query: 96 GGSGLSRLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSFGNEEQRHKFCPPLCTMEKF 155 GG G L+ + AL + Y+ + A + FG+ E + + + ++ Sbjct: 62 GGDGFGVLEQVAVLVALGHQLAAVP-YLESVVLAAGALARFGSPELQQGWGVSAVSGDRI 120 Query: 156 ASYCLT-EPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGGPGPKG 214 + L E G G A G Y L G++ + +D ++V T G Sbjct: 121 LTVALDGEMGEGP------VQAAGTGHGYRLTGTRTQVGYGPVADAFLVPAETDS----G 170 Query: 215 ISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLN 274 + +V G PG++ G S + V A R+G G +AV Sbjct: 171 AAVFLVAAGDPGVAV-TALATTGLGSV--GHLELNGAKVDAARRVG----GTDVAVWLGT 223 Query: 275 GGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVR 334 ++ + LG + +T ++ R+QF P+ S Q + LAD + RL + Sbjct: 224 LSTLSRTAFQLGVLERGLQMTAEYARTREQFDRPIGSFQAVGQRLADGYIDVKGLRLTLT 283 Query: 335 NAAVALQEE-------RKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQY 387 AA + E+ + A + A +A + + + + +HGG G D+ V +Y Sbjct: 284 QAAWRVAEDSLASRECPQPADIDVATAGFWAAEAGHRVAHTIVHVHGGVGVDTDHPVHRY 343 Query: 388 VRDSRVHQILEGSNEVMRILISRSL 412 ++ + G I R L Sbjct: 344 FLAAKQTEFALGGATGQLRRIGREL 368 >3U33-A nrPDB Length = 541 Score = 216 bits (551), Expect = 1e-56, Method: Composition-based stats. Identities = 70/289 (24%), Positives = 118/289 (40%), Gaps = 19/289 (6%) Query: 138 NEEQRHKFCPPLCTMEKFASYCLTEPGSGSDAASLLTSAKKQGDH-YILNGSKAFISGAG 196 ++ P +TE GSD S T A++ D Y L G K F S Sbjct: 162 SDRYDSHLLPGGQKRGLLIGMGMTEKQGGSDVMSNTTRAERLEDGSYRLVGHKWFFS-VP 220 Query: 197 ESDIYVVMCRTGGPGPKGISCIVVEKGTP-----GLSFGKKEKKVGWNSQPTRAVIFEDC 251 +SD ++V+ +T G G+SC V + P + + + K+G S + V F+D Sbjct: 221 QSDAHLVLAQTAG----GLSCFFVPRFLPDGQRNAIRLERLKDKLGNRSNASCEVEFQDA 276 Query: 252 AVPVANRIGSEGQGFLIAVRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLAS 311 + +G EG+G + ++ R + A S + L H + R FG PL Sbjct: 277 ---IGWLLGLEGEGIRLILKMGGMTRFDCALGSHAMMRRAFSLAIYHAHQRHVFGNPLIQ 333 Query: 312 NQYLQFTLADMATRLVAARLMVRNAAVALQEERKDAVAL-----CSMAKLFATDECFAIC 366 ++ L+ MA +L ++ A A AL AK Sbjct: 334 QPLMRHVLSRMALQLEGQTALLFRLARAWDRRADAKEALWARLFTPAAKFVICKRGMPFV 393 Query: 367 NQALQMHGGYGYLKDYAVQQYVRDSRVHQILEGSNEVMRILISRSLLQE 415 +A+++ GG GY ++ + + R+ V+ I EGS +M + + R L ++ Sbjct: 394 AEAMEVLGGIGYCEESELPRLYREMPVNSIWEGSGNIMCLDVLRVLNKQ 442 >5EZ3-A nrPDB Length = 573 Score = 215 bits (547), Expect = 4e-56, Method: Composition-based stats. Identities = 71/280 (25%), Positives = 123/280 (43%), Gaps = 20/280 (7%) Query: 147 PPLCTMEKFASYCLTEPGSGSDAASLLTSAKKQ-GDHYILNGSKAFISGAGESDIYVVMC 205 P +TE G+D + T A+ G + L G K F+S A SD ++ + Sbjct: 200 PAFRKQGVTLGMGMTEKQGGTDVRANATRAEPAIGGAWRLTGHKWFMS-APMSDAFLTLA 258 Query: 206 RTGGPGPKGISCIVVEK-----GTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIG 260 +T +G+SC ++ + + G F + + K+G S + V F+ + IG Sbjct: 259 QT----KEGLSCFLLPRLGEKGESNGFFFQRLKDKLGNRSNASSEVEFDGA---LGQMIG 311 Query: 261 SEGQGFLIAVRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLA 320 S G+G + + R++ A S G + + H R FG+PL +Q LA Sbjct: 312 SPGEGVKTIMDMVTLTRLDCAVASAGLMRSGLAEAVHHSRHRHVFGKPLVEQPLMQRVLA 371 Query: 321 DMATRLVAARLMVRNAAVALQEERKD------AVALCSMAKLFATDECFAICNQALQMHG 374 DMA + A + A A D A ++ + K + A+ +A++ G Sbjct: 372 DMALDVAGATALSMRLARAFDMAASDRAEAAFARSMTPVVKYWVCKIAPALLYEAMECLG 431 Query: 375 GYGYLKDYAVQQYVRDSRVHQILEGSNEVMRILISRSLLQ 414 G GY++D + + R++ V+ I EGS VM + ++R L + Sbjct: 432 GNGYIEDGNLARAYREAPVNAIWEGSGNVMALDVARVLSR 471 >4XVX-A nrPDB Length = 389 Score = 205 bits (523), Expect = 2e-53, Method: Composition-based stats. Identities = 78/373 (20%), Positives = 149/373 (39%), Gaps = 18/373 (4%) Query: 44 EQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGLSRL 103 + +F+ + + AE + +E FP ++ G D + +R Sbjct: 9 DLDDFRGLLAKAFDERVVAWTAEAEAQERFPRQLIEHLGVCGVF------DAKWATDARP 62 Query: 104 DTSVIFE---ALAT-GCTSTTAYISIHNMCAWMIDSFGNEEQRHKFCPPLCTMEKFASYC 159 D + E AL +S+H+ ++ FG + C Sbjct: 63 DVGKLVELAFALGQLASAGIGVGVSLHDSAIAILRRFGKSDYLRDICDQAIRGAAVLCIG 122 Query: 160 LTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCR--TGGPGPKGISC 217 +E GSD + T + + + + G K F+S + +D +V+ R P + + Sbjct: 123 ASEESGGSDLQIVETEIRSRDGGFEVRGVKKFVSLSPIADHIMVVARSVDHDPTSRHGNV 182 Query: 218 IVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGGR 277 VV +S +KVG T AV D VP + G G GL R Sbjct: 183 AVVAVPAAQVSVQTPYRKVGAGPLDTAAVCI-DTWVPADALVARAGTGLAAISWGLAHER 241 Query: 278 INIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNAA 337 ++IA + ++ +T + R+QFG+ L +Q L+ +AD+ R+ R + A Sbjct: 242 MSIAGQIAASCQRAIGITLARMMSRRQFGQTLFEHQALRLRMADLQARVDLLRYALHGIA 301 Query: 338 VALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYL-KDYAVQQYVRDSRVHQI 396 + E + A A+ A + + ++ + + GG GYL + + ++ RD ++ ++ Sbjct: 302 EQGRLELRTAAAVKVTAARLGEE----VISECMHIFGGAGYLVDETTLGKWWRDMKLARV 357 Query: 397 LEGSNEVMRILIS 409 G++EV+ L++ Sbjct: 358 GGGTDEVLWELVA 370 >4Y9J-A nrPDB Length = 593 Score = 203 bits (518), Expect = 9e-53, Method: Composition-based stats. Identities = 75/336 (22%), Positives = 137/336 (40%), Gaps = 40/336 (11%) Query: 102 RLDTSVIFEALATGCTSTTAYISI-----HNMCAWMIDSFGNEEQRHKFCPPLCTMEKFA 156 ++ +A + S+ H + +D + + + + + Sbjct: 136 SPSAGLVSCPMAMTDGAVKTLTSLNLYGKHKLATEAVDRLRSRDPSKAW----TSGQW-- 189 Query: 157 SYCLTEPGSGSDAASLLTS--AKKQGDHYILNGSKAFISGAGESDIYVVMCRTGG----- 209 +TE GSD A + + D Y L+G K F S A ++D+ + + R Sbjct: 190 ---MTEKKGGSDVAGGCDTYAVQIDKDTYRLHGYKWF-SSAVDADVALTLARIVDSDGNA 245 Query: 210 -PGPKGISCIVVE-----KGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEG 263 G +G+S +++ G+ + + K+G PT ++ + +A RIG +G Sbjct: 246 LEGSRGLSLFLLKIRDESGNLNGIQMVRLKNKLGTKQLPTAELLLDGA---IAERIGDQG 302 Query: 264 QGFLIAVRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMA 323 +G LN RI+ A SLG + L RD+ R FG+ + TLA M Sbjct: 303 RGVAGISNMLNITRIHNAVASLGYMRRIISLARDYSTKRVVFGQTQSKWPLHTTTLAKME 362 Query: 324 TRLVAARLMVRNAAV--ALQEERKDAVALCSM-------AKLFATDECFAICNQALQMHG 374 + L++ AA L E K + M KL+A + + ++ ++ G Sbjct: 363 VDTRGSMLLLFEAARLLGLSEAGKSSDVEAMMLRLITPVLKLYAGKQAVPMVSEGIECFG 422 Query: 375 GYGYLKDYAVQQYVRDSRVHQILEGSNEVMRILISR 410 G GY++D + +RD++V I EG+ V+ + + R Sbjct: 423 GQGYMEDTGLPTLLRDAQVTPIWEGTTNVLSLDVLR 458 >5Y9D-A nrPDB Length = 709 Score = 202 bits (513), Expect = 3e-52, Method: Composition-based stats. Identities = 92/476 (19%), Positives = 162/476 (34%), Gaps = 83/476 (17%) Query: 14 GCLPGGLRVLVQT-----------GHRSLTSCIDPSMGLN--EEQKEFQKVAFDFAARE- 59 G +P G + T ++ + D + LN EE+ + + R+ Sbjct: 13 GLVPRGSHMTTNTFTDPPVEMAKERGKTQFTVRDVTNFLNGGEEETQIVEKIMSSIERDP 72 Query: 60 MAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGLSRLDTSVIFEALATGCTST 119 + A++D +++A + V + + +L ST Sbjct: 73 VLSVTADYDCN-------LQQARKQTMERVAALSPYLVTDTEKLSLWRAQLH-GMVDMST 124 Query: 120 TAYISIHN-MCAWMIDSFGNEEQRHKFCPP--LCTMEKFASYCLTEPGSGSDAASLLTSA 176 +SIHN + I G EQ + + + + + +TE G GS+ L T+A Sbjct: 125 RTRLSIHNNLFIGSIRGSGTPEQFKYWVKKGAVAVKQFYGCFAMTELGHGSNLKGLETTA 184 Query: 177 K--KQGDHYILN-----GSKAFISGAGESDIYVV-MCRTGGPGPK-GISCIVVE------ 221 + D +I+N +K +I GA + + V + G G VV Sbjct: 185 TYDQDSDQFIINTPHIGATKWWIGGAAHTSTHCVCFAKLIVHGKDYGTRNFVVPLRNVHD 244 Query: 222 -KGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQ----GF-------LIA 269 G+S G KK+G + + F + +P N + + G + Sbjct: 245 HSLKVGVSIGDIGKKMGRDGVDNGWIQFTNVRIPRQNMLMRYAKVSDTGVVTKPALDQLT 304 Query: 270 VRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGE-------PLASNQYLQFTLADM 322 L GR+++ + S + + + + VR+QFG + Y Q L + Sbjct: 305 YGALIRGRVSMIADSFHVSKRFLTIALRYACVRRQFGTSGDTKETKIIDYPYHQRRLLPL 364 Query: 323 ATRLVAARLMVRNAAVALQE------------------------ERKDAVALCSMAKLFA 358 A ++ A E + K+ A + K F Sbjct: 365 LAYCYAMKMGADEAQKTWIETTDRILALNPNDPAQKNDLEKAVTDTKELFAASAGMKAFT 424 Query: 359 TDECFAICNQALQMHGGYGYLKDYAVQQYVRDSRVHQILEGSNEVMRILISRSLLQ 414 T C I ++ Q GG+GY Q D V EG N V+ + + R L+Q Sbjct: 425 TWGCAKIIDECRQACGGHGYSGYNGFGQGYADWVVQCTWEGDNNVLCLSMGRGLVQ 480 >1W07-A nrPDB Length = 659 Score = 190 bits (482), Expect = 1e-48, Method: Composition-based stats. Identities = 71/344 (20%), Positives = 123/344 (35%), Gaps = 50/344 (14%) Query: 121 AYISIH-NMCAWMIDSFGNEEQRHKFCPPLCTMEKFASYCLTEPGSGSDAASLLTSAKKQ 179 AY+ +H M I G EEQ+ K+ M+ Y TE G GS+ L T+A Sbjct: 97 AYVDLHWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATLD 156 Query: 180 G--DHYILN-----GSKAFISG-AGESDIYVVMCRTGGPGPK-GISCIVVE-------KG 223 D ++++ SK + G S VV R G GI +V+ Sbjct: 157 PKTDEFVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYGIHGFIVQLRSLEDHSP 216 Query: 224 TPGLSFGKKEKKVG---WNSQPTRAVIFEDCAVPVANRI------GSEGQGF------LI 268 P ++ G K+G +NS ++F+ +P + EG+ + Sbjct: 217 LPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQL 276 Query: 269 AVRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGE-------PLASNQYLQFTLAD 321 + R I + + A +V + + VR+QFG + + Q L Sbjct: 277 VYGTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFP 336 Query: 322 MATRLVAARL-----------MVRNAAVALQEERKDAVALCSMAKLFATDECFAICNQAL 370 + A R + A + +A A + K T + Sbjct: 337 LLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEECR 396 Query: 371 QMHGGYGYLKDYAVQQYVRDSRVHQILEGSNEVMRILISRSLLQ 414 ++ GG+GYL + + EG N V+++ ++R L++ Sbjct: 397 KLCGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFLMK 440 >2FON-A nrPDB Length = 683 Score = 183 bits (464), Expect = 2e-46, Method: Composition-based stats. Identities = 71/344 (20%), Positives = 126/344 (36%), Gaps = 50/344 (14%) Query: 121 AYISIH-NMCAWMIDSFGNEEQRHKFCPPLCTMEKFASYCLTEPGSGSDAASLLTSAK-- 177 A+ +H M I G ++Q+ K+ P M+ Y TE G GS+ L T+A Sbjct: 116 AFTDLHWGMFIPAIKGQGTDKQQEKWLPLAYKMQIIGCYAQTELGHGSNVQGLETTATFD 175 Query: 178 KQGDHYILN-----GSKAFISG-AGESDIYVVMCRTGGPGPK-GISCIVVE-------KG 223 Q D ++++ SK + G S VV R G G++ +V+ K Sbjct: 176 PQTDEFVIHSPTLTSSKWWPGGLGKVSTHAVVYARLITDGKDYGVNGFIVQLRSLEDHKP 235 Query: 224 TPGLSFGKKEKKVG---WNSQPTRAVIFEDCAVPVANRI------GSEGQ------GFLI 268 PG++ G K G +NS + F+ +P + EG+ + Sbjct: 236 LPGVTVGDIGMKFGNGAYNSMDNGVLSFDHVRIPRDQMLMRVSQVTKEGKYVQSDIPRQL 295 Query: 269 AVRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFG-------EPLASNQYLQFTLAD 321 + R +I + + A +V + + VR+QFG + + Q L Sbjct: 296 LYGTMVYVRQSIVADASLAMSRAVCIATRYSAVRRQFGSQNGGQETQVIDYKTQQNRLFP 355 Query: 322 MATRLVAARL-----------MVRNAAVALQEERKDAVALCSMAKLFATDECFAICNQAL 370 + A R + + A +A A + K T + Sbjct: 356 LLASAYAFRFVGEWLKWLYTDVTQRLAANDFSTLPEAHACTAGLKSLTTSATADGIEECR 415 Query: 371 QMHGGYGYLKDYAVQQYVRDSRVHQILEGSNEVMRILISRSLLQ 414 ++ GG+GYL + + EG N V+++ ++R L++ Sbjct: 416 KLCGGHGYLCSSGLPELFAVYVPACTYEGDNVVLQLQVARFLMK 459 >5XDD-A nrPDB Length = 414 Score = 179 bits (455), Expect = 2e-45, Method: Composition-based stats. Identities = 69/386 (17%), Positives = 129/386 (33%), Gaps = 29/386 (7%) Query: 38 SMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGG 97 S + E+ + VA + A + E ++ P + G + I + GG Sbjct: 8 SSAVREDHRAL-DVATELAKTFRV-TVRERERAGGTPKAERDAIRRSGLLTLLISKERGG 65 Query: 98 SGLSRLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSFGNEEQRHKFCPPLCTMEKFAS 157 G S +A+ S H +D F + EQ+ ++ P F Sbjct: 66 LGESWPTVYEAIAEIASADASLGHLFGYHFSNFAYVDLFASPEQKARWYPQAVRERWFLG 125 Query: 158 YCLTEPGSGSDAASLLTSAKKQGDH-YILNGSKAFISGAGESDIYVVMCRT--GGPGPKG 214 +E + +A D Y +NG+KAF SG+ ++D +V T G Sbjct: 126 NASSENNA--HVLDWRVTATPLPDGSYEINGTKAFCSGSADADRLLVFAVTSRDPNGDGR 183 Query: 215 ISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLN 274 I ++ G+ +G + +V F V +G+ GQ G Sbjct: 184 IVAALIPSDRAGVQVNGDWDSLGMRQTDSGSVTFSGVVVYPDELLGTPGQVTDAFASGSK 243 Query: 275 GG------RINIASCSLGAAHASVILTRDHLNVRK-----QFGEPLASNQYLQFTLADMA 323 ++ LG A ++ + E + Y+ + A Sbjct: 244 PSLWTPITQLIFTHLYLGIARGALEEAAHYSRSHSRPFTLAGVEKATEDPYVLAIYGEFA 303 Query: 324 TRLVAARLMVRNAAVALQ----------EERKDAVALCSMAKLFATDECFAICNQALQMH 373 +L A R A+ +Q E+R + + AK+ AT + ++ + Sbjct: 304 AQLQVAEAGAREVALRVQELWERNHVTPEQRGQLMVQVASAKIVATRLVIELTSRLYEAM 363 Query: 374 GG-YGYLKDYAVQQYVRDSRVHQILE 398 G + + ++ RD+R H + + Sbjct: 364 GARAAASRQFGFDRFWRDARTHTLHD 389 >1IS2-A nrPDB Length = 661 Score = 155 bits (391), Expect = 4e-38, Method: Composition-based stats. Identities = 66/333 (19%), Positives = 110/333 (33%), Gaps = 45/333 (13%) Query: 127 NMCAWMIDSFGNEEQRHKFCPPLCTMEKFASYCLTEPGSGSDAASLLTSAKKQGD--HYI 184 M + EQ+ +F P +E +Y TE G G+ L T+A +I Sbjct: 105 GMFLPTLLHQATAEQQERFFMPAWNLEITGTYAQTEMGHGTHLRGLETTATYDPKTQEFI 164 Query: 185 LNGS-----KAFISGAGE-SDIYVVMCRTGGPGP-KGISCIVVE-------KGTPGLSFG 230 LN K + G G+ S+ +V+ + G G+ VV K PG++ G Sbjct: 165 LNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVG 224 Query: 231 KKEKKVGWNSQPTRAVIFEDCAVPVANRI------GSEGQGFLIAVRGLNGG-----RIN 279 K G+ + ++ +P N + +G L G R Sbjct: 225 DIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSF 284 Query: 280 IASCSLGAAHASVILTRDHLNVRKQF------GEP-LASNQYLQFTLADMATRLVAARLM 332 + + + + + + VR+Q EP + Q Q+ L + A + Sbjct: 285 LVGNAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFV 344 Query: 333 VRNAAVALQ-----------EERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKD 381 R E + AL + K F T A + GG+GY Sbjct: 345 GRYMKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHS 404 Query: 382 YAVQQYVRDSRVHQILEGSNEVMRILISRSLLQ 414 + EG N VM + +R L++ Sbjct: 405 SGIPNIYVTFTPACTFEGENTVMMLQTARFLMK 437 >5K3G-A nrPDB Length = 684 Score = 141 bits (357), Expect = 4e-34, Method: Composition-based stats. Identities = 65/338 (19%), Positives = 119/338 (35%), Gaps = 46/338 (13%) Query: 123 ISIHN-MCAWMIDSFGNEEQRHKFCPPLCTMEKFASYCLTEPGSGSDAASLLTSAKKQGD 181 +++H M +++ ++EQ+ K+ E +Y TE G G++ +L T+A Sbjct: 113 MALHGVMFIPALNAQASDEQQAKWLIRALRREIIGTYAQTEMGHGTNLQNLETTATYDIG 172 Query: 182 --HYILN-----GSKAFISGAGE-SDIYVVMCRTGGPGPK-GISCIVVE-------KGTP 225 ++L+ K + G+ S+ VV+ G G +V K P Sbjct: 173 TQEFVLHTPKITALKWWPGNLGKSSNYAVVVAHMYIKGKNFGPHTFMVPLRDEKTHKPLP 232 Query: 226 GLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGS----EGQGF-------LIAVRGLN 274 G++ G K+ +N + F + +P N + E G I + Sbjct: 233 GITIGDIGPKMAYNIVDNGFLGFNNYRIPRTNLLMRHTKVEADGTYIKPPHAKINYSAMV 292 Query: 275 GGRINIASCSLGAAHASVILTRDHLNVRKQF----GEP---LASNQYLQFTLADMATRLV 327 R + + ++ + + VR+Q EP + Q Q L R Sbjct: 293 HVRSYMLTGQAIMLSYALNIATRYSAVRRQGQIDKNEPEVKVLEYQTQQHRLFPFIARAY 352 Query: 328 AARL-------MVRNAAVALQEER----KDAVALCSMAKLFATDECFAICNQALQMHGGY 376 A + + ++ D AL S K T + QA GG+ Sbjct: 353 AFQFAGAETVKLYERVLKEMKSGNVSLMADLHALTSGLKSVVTHQTGEGIEQARMACGGH 412 Query: 377 GYLKDYAVQQYVRDSRVHQILEGSNEVMRILISRSLLQ 414 GY + + + EG N VM + ++R L++ Sbjct: 413 GYSMASYISEIYGVAIGGCTYEGENMVMLLQLARYLVK 450 >5K3J-A nrPDB Length = 674 Score = 131 bits (329), Expect = 6e-31, Method: Composition-based stats. Identities = 64/342 (18%), Positives = 115/342 (33%), Gaps = 48/342 (14%) Query: 120 TAYISIHN-MCAWMIDSFGNEEQRHKFCPPLCTMEKFASYCLTEPGSGSDAASLLTSAKK 178 ++H+ + + S ++EQ+ K+ E Y TE G GS+ +L T+A Sbjct: 108 GHPFALHDALFIPTLQSQASDEQQEKWLERARRREIIGCYAQTELGHGSNLRNLETTAVY 167 Query: 179 Q--GDHYILN-----GSKAFISGAGES-DIYVVMCRTGGPGPK-GISCIVVEK------- 222 ++L+ K + G+S + +V+ G +V+ Sbjct: 168 DIASQEFVLHTPTTTALKWWPGALGKSCNYALVVAELIIKRNNYGPHFFMVQLRDEKTHI 227 Query: 223 GTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGS----EGQGF-------LIAVR 271 G++ G K+ +N+ + + VP N + E G I Sbjct: 228 PLKGVTVGDIGPKMNFNAADNGYLGLNNLRVPRTNLLMRHCKVEADGTYVKPPHAKIGYS 287 Query: 272 GLNGGRINIAS-CSLGAAHASVILTRDHLNVRKQF-------GEPLASNQYLQFTLADMA 323 G+ R +A L AH ++ + + VR+Q + Q Q L Sbjct: 288 GMVKIRSQMAMEQGLFLAH-ALTIAARYSAVRRQGHLDDKQVEVKVLDYQTQQHRLFPSL 346 Query: 324 TRLVAA-----------RLMVRNAAVALQEERKDAVALCSMAKLFATDECFAICNQALQM 372 R A ++++ + D AL S K E QA Sbjct: 347 ARAYAFIFTGFETIHLYSQLLKDVDMGNTSGMADLHALTSGLKSVVAHETGEGIEQARMA 406 Query: 373 HGGYGYLKDYAVQQYVRDSRVHQILEGSNEVMRILISRSLLQ 414 GG+GY + + G N VM + ++R L++ Sbjct: 407 CGGHGYSMASYISVVYGIAIGGCTYAGENMVMLLQLARYLVK 448 >2JBS-A nrPDB Length = 422 Score = 107 bits (267), Expect = 1e-23, Method: Composition-based stats. Identities = 59/384 (15%), Positives = 125/384 (32%), Gaps = 49/384 (12%) Query: 59 EMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGLSRLDTSVIFEALATGCTS 118 ++A N +Q P + ++ ++G + GG +S D + LA C Sbjct: 50 QIAKNAESAEQLRRVPDENIKLLKEIGLHRAFQPKVYGGLEMSLPDFANCIVTLAGACAG 109 Query: 119 TTAYISIHNMCAWMIDSFGNEEQRHKFC--PPLCTMEKFASYCLTEPGSGSDAASLLTSA 176 T S+ + I F + Q + P A + E Sbjct: 110 TAWAFSLLCTHSHQIAMFSKQLQDEIWLKDPDATASSSIAPFGKVE-------------- 155 Query: 177 KKQGDHYILNGSKAFISGAGESDIYVV-MCRTGGPGPKGISCIVVEKGTPGLSFGKKEKK 235 + ILNG + SG ++ +V R G K S V+ + Sbjct: 156 -EVEGGIILNGDYGWSSGCDHAEYAIVGFNRFDADGNKIYSFGVIPRSD--YEIVDNWYA 212 Query: 236 VGWNSQPTRAVIFEDCAVP------VANRIGSEGQGF------LIAVRGLN-GGRINIAS 282 S ++ + + +P + + + GF I ++ Sbjct: 213 QAIKSSGSKMLKLVNVFIPEYRISKAKDMMEGKSAGFGLYPDSKIFYTPYRPYFASGFSA 272 Query: 283 CSLGAAHASVILTRDHLNVRKQ--FGEPLASNQYLQFTLADMATRLVAARLMVRNAAVAL 340 SLG A + ++ R + G + +A+ ++ AAR ++ Sbjct: 273 VSLGIAERMIEAFKEKQRNRVRAYTGANVGLATPALMRIAESTHQVAAARALLEK---TW 329 Query: 341 QEER----------KDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRD 390 ++ R K+ +A + +A C ++ + G ++ + +Q+ RD Sbjct: 330 EDHRIHGLNHQYPNKETLAFWRTNQAYAVKMCIEAVDRLMAAAGATSFMDNSELQRLFRD 389 Query: 391 SRVHQILEGSN-EVMRILISRSLL 413 + + ++ +V ++ R L+ Sbjct: 390 AHMTGAHAYTDYDVCAQILGRELM 413 >5LVW-A nrPDB Length = 413 Score = 102 bits (255), Expect = 3e-22, Method: Composition-based stats. Identities = 82/408 (20%), Positives = 142/408 (34%), Gaps = 65/408 (15%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELF 73 G +P G + T + L E + F A +AE +++ Sbjct: 9 GLVPRGSHM---------TDIRSETAELRAE---LVERVHKFG-PVFADGVAEGERERRL 55 Query: 74 PVDVMRKAAQLGFGGVYIQTDVGGSGLSRLDTSVIFEALATGCTSTTAYISIHNMCAWMI 133 P +R Q ++ GG S + + L+ C ST+ ++ N Sbjct: 56 PDATVRAIDQSQLAMLWTAKSYGGLETDVRTMSEVAKVLSHYCPSTSWVVNNVN------ 109 Query: 134 DSFGNEEQRHKFCPPLCTMEKFASYCLTEPGSG-SDAASLLTSAKKQGDHYILNGSKAFI 192 G+ KF P +++ PG+ + + +A + Y L GS + Sbjct: 110 ---GSNLLASKF--PRAALDEVFGDA---PGAKLASVFAAAGTAVRTPGGYRLTGSWPYG 161 Query: 193 SGAGESDIYVVMCRT---GGPGPKGISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFE 249 +G D +++ R G G+S +V + L+ VG + + V+ Sbjct: 162 TGILHDDWAILVAREVDADGEPVGGLSMLVPARD---LTVEDTWHTVGMRATGSHTVVLR 218 Query: 250 DCAVPVANRIGSE-----------GQGFLIAVRGLNGGRINIASCSLGAAHASVILTRDH 298 D VP I E G L + + AS LGA A+ L + Sbjct: 219 DTFVPEHRVISGELQRSRESATDLGLPPLFRTAAIAAMAVVCASVVLGAGQAARALVVEK 278 Query: 299 LNVRKQFGEPLASNQYLQFT--------LADMATRLVAARLMVRNAAVALQEERKDAVA- 349 R +A ++Y + T L A + AA + V AA AL + DAVA Sbjct: 279 APTRG-----IAPSKYTRQTDSRTFVSSLGRTALSIDAAEMHVARAATALDDAAYDAVAL 333 Query: 350 -LCSMAKLFA-TDECFAICNQALQ----MHGGYGYLKDYAVQQYVRDS 391 + ++ + ++ AL HG + + +Q+Y RD+ Sbjct: 334 PDSELLRIRGDVGQAVSLVTTALDELLWAHGAASFAESNPLQRYWRDA 381 >2RFQ-A nrPDB Length = 394 Score = 101 bits (251), Expect = 8e-22, Method: Composition-based stats. Identities = 63/378 (16%), Positives = 123/378 (32%), Gaps = 42/378 (11%) Query: 42 NEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGLS 101 + E + E + P D M+ + GF + GG Sbjct: 9 SHEVMQRLDALLPTLRER----AQETEDLRRIPDDSMKALQETGFFRLLQPEQWGGYQAD 64 Query: 102 RLDTSVIFEALATGCTSTTAYISIHNMCAWMIDSFGNEEQRHKFCPPLCTMEKFASYCLT 161 + +A+ C ST SI + W + F + Q + + S Sbjct: 65 PVLFYSAVRKIASACGSTGWVSSIIGVHNWHLALFSQQAQEDVWG---NDTDVRISSSYA 121 Query: 162 EPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGGPG-PKGISCIVV 220 G+G + Y +NG+ A+ SG + V+ G P ++ Sbjct: 122 PMGAG----------QVVDGGYTVNGAWAWSSGCDHASWAVLGGPVIKDGRPVDFVSFLI 171 Query: 221 EKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANR--------IGSEG-QGFLIAVR 271 + VG + V+ ED VP + + G + V Sbjct: 172 PRED--YRIDDVWNVVGLRGTGSNTVVVEDVFVPTHRVLSFKAMSNLTAPGLERNTAPVY 229 Query: 272 GLNGGRIN---IASCSLGAAHASVILTRDH--LNVRKQF-GEPLASNQYLQFTLADMATR 325 + G I+ I++ +G A+ + +H VR F GE + + + +A+ ++ Sbjct: 230 KMPWGTIHPTTISAPIVGMAYGAYDAHVEHQGKRVRAAFAGEKAKDDPFAKVRIAEASSD 289 Query: 326 LVAA-RLMVRNAAVAL------QEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGY 378 + AA R + N A +E + ++ AT + ++ + G Sbjct: 290 IDAAWRQLSGNVADEYALLVAGEEVPFELRLRARRDQVRATGRAISSIDKLFESSGATAL 349 Query: 379 LKDYAVQQYVRDSRVHQI 396 +Q++ RD+ ++ Sbjct: 350 ANGTPLQRFWRDAHAGRV 367 >3AFF-A nrPDB Length = 394 Score = 95.0 bits (235), Expect = 5e-20, Method: Composition-based stats. Identities = 62/364 (17%), Positives = 122/364 (33%), Gaps = 42/364 (11%) Query: 60 MAPNMAEWDQKEL----FPVDVMRKAAQLGFGGVYIQTDVGGSGLSRLDTSVIFEALATG 115 + P + + Q P + ++ +GF + GG LA+ Sbjct: 19 LLPEIRDRAQATEDLRRLPDETVKALDDVGFFTLLQPQQWGGLQCDPALFFEATRRLASV 78 Query: 116 CTSTTAYISIHNMCAWMIDSFGNEEQRHKFCPPLCTMEKFASYCLTEPGSGSDAASLLTS 175 C ST SI + W + F Q + + +SY G+G Sbjct: 79 CGSTGWVSSIVGVHNWHLALFDQRAQEEVWGED-PSTRISSSYA--PMGAG--------- 126 Query: 176 AKKQGDHYILNGSKAFISGAGESDIYVVMCRTGGPG-PKGISCIVVEKGTPGLSFGKKEK 234 Y++NGS + SG + V G P ++ + Sbjct: 127 -VVVDGGYLVNGSWNWSSGCDHASWTFVGGPVIKDGRPVDFGSFLIPRSE--YEIKDVWY 183 Query: 235 KVGWNSQPTRAVIFEDCAVPVANRIGSEG-----QGFLIAVRG----LNGGRIN---IAS 282 VG + ++ +D VP + + G L + G ++ I++ Sbjct: 184 VVGLRGTGSNTLVVKDVFVPRHRFLSYKAMNDHTAGGLATNSAPVYKMPWGTMHPTTISA 243 Query: 283 CSLGAAHASVILTRDH--LNVRKQF-GEPLASNQYLQFTLADMATRLVAA-RLMV----- 333 +G A+ + +H VR F GE + + + +A+ A+ + AA R ++ Sbjct: 244 PIVGMAYGAYAAHVEHQGKRVRAAFAGEKAKDDPFAKVRIAEAASDIDAAWRQLIGNVSD 303 Query: 334 -RNAAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQQYVRDSR 392 A +E + A ++ AT A ++ + G + +Q++ RD+ Sbjct: 304 EYALLAAGKEIPFELRARARRDQVRATGRSIASIDRLFEASGATALSNEAPIQRFWRDAH 363 Query: 393 VHQI 396 ++ Sbjct: 364 AGRV 367 >2OR0-A nrPDB Length = 414 Score = 72.6 bits (177), Expect = 3e-13, Method: Composition-based stats. Identities = 42/365 (11%), Positives = 106/365 (29%), Gaps = 44/365 (12%) Query: 54 DFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTDVGGSGLSRLDTSVIFEALA 113 + A E+ + + G + GG + + + +A Sbjct: 30 EVVAEEIRGQAVQSEADCRLTDAAAGLLRDSGAIRLLQPRLYGGYEVHPREFAETVMGVA 89 Query: 114 TGCTSTTAYISIHNMCAWMIDSFGNEEQRHKFCPPLCTMEKFASYCLTEPGSGSDAASLL 173 ++ I + W + + Q + E ++ + + + Sbjct: 90 ALDGASGWVTGIVGVHPWELAFADPQVQEEIW------GEDNDTWMAS-------PYAPM 136 Query: 174 TSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGGPGPKGISCI-----VVEKGTPGLS 228 A Y+L G +F SG + G G GI+ ++ + + Sbjct: 137 GVATPVDGGYVLKGRWSFSSGTDHCQWAFLGAMVGD-GEGGIATPSSLHVILPRTDYQI- 194 Query: 229 FGKKEKKVGWNSQPTRAVIFEDCAVPVANRI--------------GSEGQGFLIAVRGLN 274 +G ++ +I + VP + G F + + Sbjct: 195 VEDTWDVIGLRGTGSKDLIVDGAFVPGYRTLNAAKVMDGRAQKEAGRPEPLFNMPYSCMF 254 Query: 275 GGRINIASCSLGAAHASVILTRDHLNVRKQF-GEPLASNQYLQFTLADMATRLVAARLMV 333 + I + +G ++ R G+ + + Y+ + + A + A+R+ + Sbjct: 255 P--LGITAAVIGITEGALACHIAVQKDRVAITGQKIKEDPYVLSAIGESAAEINASRVSL 312 Query: 334 RNAAVA----LQEERKDAVALCSMAKLFATDECFAICNQALQMH---GGYGYLKDYAVQQ 386 A + ++ ++ + + A ++ GG +Q+ Sbjct: 313 IETADRFYDKVDAGKEITFEERAIGRRTQIAAAWRAVRAADEIFARAGGGALHYKTPMQR 372 Query: 387 YVRDS 391 + RD+ Sbjct: 373 FWRDA 377 >3WG8-A nrPDB Length = 227 Score = 44.9 bits (105), Expect = 6e-05, Method: Composition-based stats. Identities = 12/51 (23%), Positives = 22/51 (43%), Gaps = 2/51 (3%) Query: 14 GCLPGGLRVLVQTGHRSLTSCID--PSMGLNEEQKEFQKVAFDFAAREMAP 62 G +P G + TG + + + PS EE+ E + +F ++ P Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSEFMPSELTPEERSELKNSIAEFHTYQLDP 63 >3HWC-A nrPDB Length = 515 Score = 44.9 bits (105), Expect = 7e-05, Method: Composition-based stats. Identities = 56/283 (19%), Positives = 85/283 (30%), Gaps = 45/283 (15%) Query: 52 AFDFAAREMAPNMAEWDQKELFPVDVMRKAAQL-GFGG---VYIQTDVGGSGLSRLDTSV 107 D+A R +D + + G D G + R Sbjct: 33 TRDYAERV----AQFYDLHHRPDLQDVLTFVDADGVRRSRQWQDPKDAAGLRVKRKYHET 88 Query: 108 IFEALATGCTSTTAYISIHNMC---------AWMIDSFGNE-----EQRHKFCPPLCTME 153 I +A G S HN W S G E + H F L + Sbjct: 89 ILREIAAG--SYGRLPDAHNYTFTTYADDPEVWEKQSIGAEGRNLTQNIHNFLKLLREKD 146 Query: 154 KFASYCLTEPGS--GSDAASLLT----SAKKQGDHYILNGSKAFISGAGESDIYVVMC-- 205 +P + SDAA + +K D I+NG KA +G D + C Sbjct: 147 LNCPLNFVDPQTDRSSDAAQARSPNLRIVEKTDDGIIVNGVKAVGTGIAFGDYMHIGCLY 206 Query: 206 RTGGPGPKGISCIVVEKGTPGLSFGKKEKKVGWNSQPT----------RAVIFEDCAVPV 255 R G PG + I + TPG++ +E V + +F++ +P Sbjct: 207 RPGIPGEQVIFAAI-PTNTPGVTVFCRESTVKNDPAEHPLASQGDELDSTTVFDNVFIPW 265 Query: 256 ANR--IGSEGQGFLIAVRGLNGGRINIASCSLGAAHASVILTR 296 IG+ L R + +I + A V L Sbjct: 266 EQVFHIGNPEHAKLYPQRIFDWVHYHILIRQVLRAELIVGLAI 308 >6MSO-A nrPDB Length = 585 Score = 41.8 bits (97), Expect = 5e-04, Method: Composition-based stats. Identities = 11/80 (13%), Positives = 26/80 (32%), Gaps = 9/80 (11%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELF 73 G +P G + TG + + + +++A A P +++ KE Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSEF---------MLRRLAPLLAEFNFVPLVSKVSHKETK 63 Query: 74 PVDVMRKAAQLGFGGVYIQT 93 + + + G + Sbjct: 64 YRLLTKDYVSVVQPGAGLPE 83 >4M03-A nrPDB Length = 210 Score = 41.8 bits (97), Expect = 6e-04, Method: Composition-based stats. Identities = 8/39 (20%), Positives = 16/39 (41%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLNEEQKEFQKVA 52 G +P G + TG + + P++ + + E K Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSAPTVTVGNQTIEVGKTM 51 >3PSP-A nrPDB Length = 425 Score = 41.1 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 12/93 (12%), Positives = 24/93 (25%), Gaps = 10/93 (10%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELF 73 G +P G + TG + + P + Q + + + F Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSSPY-------EILQSPGRKEGQIVVVKSPQGTIEAHQF 65 Query: 74 PVDVMRKAAQ---LGFGGVYIQTDVGGSGLSRL 103 +K G G + + G + Sbjct: 66 SNSSWKKVGDVVGAGATGNDKKIEFEGKTYDYV 98 >5CHZ-A nrPDB Length = 192 Score = 40.7 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 8/38 (21%), Positives = 17/38 (44%), Gaps = 1/38 (2%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLNEEQKEFQKV 51 G +P G + TG + + + M L+ +++ K Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSEF-MALSPPRRKAFKK 49 >1U8V-A nrPDB Length = 490 Score = 39.5 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 46/308 (14%), Positives = 96/308 (31%), Gaps = 68/308 (22%) Query: 116 CTSTTAYISIHNMCAWMIDSFGNEEQRH--KFCPPLCTMEKFASYCLTEPGSGSDAASLL 173 C A+ ++ + + +G ++ ++ + + +T+P L Sbjct: 103 CVGMDAFNAVFSTTYEIDQKYGTNYHKNFTEYLKYIQENDLIVDGAMTDPKG---DRGLA 159 Query: 174 TSAKKQ-----------GDHYILNGSKAFISGAGESDIYVVM---CRTGGPGPKGISCIV 219 SA+K D ++ G+KA +G+ S +++M T +S Sbjct: 160 PSAQKDPDLFLRIVEKREDGIVVRGAKAHQTGSINSHEHIIMPTIAMTEADKDYAVS-FA 218 Query: 220 VEKGTPGLSFG---------KKEKK----VGWNSQPTRA--VIFEDCAVPVANRIGSEGQ 264 GL K E+ +G + V+F++ +P + Sbjct: 219 CPSDADGLFMIYGRQSCDTRKMEEGADIDLGNKQFGGQEALVVFDNVFIPNDRIFLCQEY 278 Query: 265 GFLIAV---------RGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYL 315 F + + G ++ + +GAA L D+ +K ++ Sbjct: 279 DFAGMMVERFAGYHRQSYGGCKVGVGDVVIGAA----ALAADYNGAQKA--------SHV 326 Query: 316 QFTLADMATRLVAARLMVRNAAVALQEERKDAVA--------LCSMAKLFATDECFAICN 367 + L +M + +A E A L ++ K T + I Sbjct: 327 KDKLIEMTHLNE----TLYCCGIACSAEGYPTAAGNYQIDLLLANVCKQNITRFPYEIVR 382 Query: 368 QALQMHGG 375 A + GG Sbjct: 383 LAEDIAGG 390 >2YYI-A nrPDB Length = 481 Score = 39.5 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 35/199 (17%), Positives = 62/199 (31%), Gaps = 23/199 (11%) Query: 163 PGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRT--GGPGPKGISCIVV 220 P D + K+ ++ G++ + +D ++ T K + Sbjct: 155 PSGQPDPYIPVGVVKQTEKGIVVRGARMTATF-PLADEVLIFPSTLLQAGSEKYALAFAL 213 Query: 221 EKGTPGLSFGKKEKKVGWNS------QPTRA-----VIFEDCAVPVANR--IGSEG--QG 265 TPGL F +E VG +S VIF+D VP +G+ Sbjct: 214 PTSTPGLHFVCREALVGGDSPFDHPLSSRVEEMDCLVIFDDVLVPWERVFILGNVELCNN 273 Query: 266 FLIAVRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATR 325 A LN + + A + + G + + +Q +A++ Sbjct: 274 AYAATGALNHMAHQVVALKTAKTEAFLGVAALMAEG---IGADVYGH--VQEKIAEIIVY 328 Query: 326 LVAARLMVRNAAVALQEER 344 L A R A +E Sbjct: 329 LEAMRAFWTRAEEEAKENA 347 >4XBS-A nrPDB Length = 265 Score = 38.4 bits (88), Expect = 0.007, Method: Composition-based stats. Identities = 9/32 (28%), Positives = 14/32 (43%), Gaps = 1/32 (3%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLNEEQ 45 G +P G + TG + + + M L EQ Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSEF-MTLTTEQ 43 >4OTK-A nrPDB Length = 318 Score = 38.0 bits (87), Expect = 0.008, Method: Composition-based stats. Identities = 10/45 (22%), Positives = 17/45 (37%), Gaps = 11/45 (24%) Query: 14 GCLPGGLRVLVQTGHRSLTSCID-----------PSMGLNEEQKE 47 G +P G + TG + + + PS+ LN+E Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSEFVTGESGAAAAPSITLNDEHTM 57 >4NRS-A nrPDB Length = 449 Score = 37.6 bits (86), Expect = 0.009, Method: Composition-based stats. Identities = 11/89 (12%), Positives = 26/89 (29%), Gaps = 14/89 (15%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELF 73 G +P G + TG + + + + K + + W L Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSEFAFVKIASD---GKGFTRYGEPYLIRGANYWQGMNLG 69 Query: 74 PVD-----------VMRKAAQLGFGGVYI 91 D +++ A++G + + Sbjct: 70 ADDCSGGDRKRMELEIKQMAEMGINNLRV 98 >5JYK-A nrPDB Length = 566 Score = 37.6 bits (86), Expect = 0.010, Method: Composition-based stats. Identities = 8/38 (21%), Positives = 16/38 (42%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLNEEQKEFQKV 51 G +P G + TG + + + + NE + Q+ Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSEFELLNNESEAGNQRT 50 >5ILA-A nrPDB Length = 301 Score = 37.6 bits (86), Expect = 0.010, Method: Composition-based stats. Identities = 8/38 (21%), Positives = 16/38 (42%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLNEEQKEFQKV 51 G +P G + TG + + + + NE + Q+ Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSEFELLNNESEAGNQRT 50 >3ZF4-A nrPDB Length = 204 Score = 37.6 bits (86), Expect = 0.011, Method: Composition-based stats. Identities = 22/118 (18%), Positives = 33/118 (27%), Gaps = 10/118 (8%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELF 73 G +P G + TG + + SM + K K A + E Sbjct: 13 GLVPRGSHMASMTGGQQMGRG---SMTNTLQVKLLSKNARMPERNHKTDAGYDIFSAETV 69 Query: 74 PVDVMRKAAQLGFGGVYIQTDVGG-----SGLSRLDTSVIFEALATGCTSTTAYISIH 126 ++ KA V I G SG+S VI + I+ Sbjct: 70 VLEPQEKAVIKTDVAVSIPEGYVGLLTSRSGVSSKTHLVI--ETGKIDAGAHGNLGIN 125 >3LNB-A nrPDB Length = 309 Score = 37.2 bits (85), Expect = 0.013, Method: Composition-based stats. Identities = 14/71 (19%), Positives = 25/71 (35%), Gaps = 6/71 (8%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLNEEQKEFQKVAFDFAAREMAPNMAE--WDQKE 71 G +P G + TG + + + QKEF K A ++ E + Sbjct: 9 GLVPRGSHMASMTGGQQMGRGS----MMTNLQKEFFKRLKIPAKEITFNDLDEILLNMGM 64 Query: 72 LFPVDVMRKAA 82 + P + + A Sbjct: 65 ILPFENLDIMA 75 >6MSN-A nrPDB Length = 604 Score = 37.2 bits (85), Expect = 0.014, Method: Composition-based stats. Identities = 7/31 (22%), Positives = 14/31 (45%), Gaps = 1/31 (3%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLNEE 44 G +P G + TG + + + M L ++ Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSEF-MSLCDQ 42 >5GVX-A nrPDB Length = 430 Score = 37.2 bits (85), Expect = 0.014, Method: Composition-based stats. Identities = 18/127 (14%), Positives = 36/127 (28%), Gaps = 22/127 (17%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLNEEQKEFQKVAFDFAAREMAPNMAEW---DQK 70 G +P G + TG + + + + V + P + D Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSEFEL-----------VVRKLGPVTIDPRRHDAVLFDTT 61 Query: 71 ELFPVDVMRKAAQLGFGGVYIQTDVGGSGLSRLDTSVIFEALATGCTSTTAYISIHNMCA 130 +++R+ ++G G GSGL ++ +S H+ Sbjct: 62 LDATQEMVRQLQEVGVGTGVF-----GSGLDVP---IVAAGRLAVRPGRCVVVSAHSAGV 113 Query: 131 WMIDSFG 137 G Sbjct: 114 TAARESG 120 >5Z6H-A nrPDB Length = 563 Score = 37.2 bits (85), Expect = 0.014, Method: Composition-based stats. Identities = 8/54 (14%), Positives = 19/54 (35%), Gaps = 4/54 (7%) Query: 14 GCLPGGLRVLVQTGHRSLTSCID----PSMGLNEEQKEFQKVAFDFAAREMAPN 63 G +P G + TG + + + P+ + D + ++ P+ Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSEFDDNPATQTTSPDILLGPLFNDVQSAKLFPD 66 >3LBE-A nrPDB Length = 163 Score = 37.2 bits (85), Expect = 0.014, Method: Composition-based stats. Identities = 7/30 (23%), Positives = 12/30 (40%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLNE 43 G +P G + TG + + L+E Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSMSDNHLHE 42 >6CF1-A nrPDB Length = 138 Score = 36.8 bits (84), Expect = 0.017, Method: Composition-based stats. Identities = 6/41 (14%), Positives = 14/41 (34%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLNEEQKEFQKVAFD 54 G +P G + TG + + ++ + + D Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSMRQFKVSHPGEMIARDLED 53 >5K53-A nrPDB Length = 262 Score = 36.8 bits (84), Expect = 0.017, Method: Composition-based stats. Identities = 11/60 (18%), Positives = 22/60 (36%), Gaps = 1/60 (1%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLNE-EQKEFQKVAFDFAAREMAPNMAEWDQKEL 72 G +P G + TG + + + L +FQ + A + + E +Q+ Sbjct: 9 GLVPRGSHMASMTGGQQMGRGSEFMPQLEASPTIDFQTETYKDAYSRINAIVIEGEQEAH 68 >5C1S-A nrPDB Length = 391 Score = 36.8 bits (84), Expect = 0.018, Method: Composition-based stats. Identities = 7/36 (19%), Positives = 13/36 (36%), Gaps = 3/36 (8%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLNEEQKEFQ 49 G +P G + TG + + SM + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRG---SMAMIRPAHMIR 45 >5U50-A nrPDB Length = 265 Score = 36.8 bits (84), Expect = 0.019, Method: Composition-based stats. Identities = 5/26 (19%), Positives = 11/26 (42%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSM 39 G +P G + TG + + + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSEFEL 38 >3VT2-A nrPDB Length = 526 Score = 36.4 bits (83), Expect = 0.021, Method: Composition-based stats. Identities = 5/25 (20%), Positives = 11/25 (44%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPS 38 G +P G + TG + + + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSEFA 37 >4H27-A nrPDB Length = 364 Score = 36.4 bits (83), Expect = 0.022, Method: Composition-based stats. Identities = 6/26 (23%), Positives = 11/26 (42%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSM 39 G +P G + TG + + + M Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSEFMM 38 >3OXG-A nrPDB Length = 464 Score = 36.4 bits (83), Expect = 0.024, Method: Composition-based stats. Identities = 7/32 (21%), Positives = 13/32 (40%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLNEEQ 45 G +P G + TG + + + L E+ Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSEFMEPLKVEK 44 >4KML-A nrPDB Length = 241 Score = 36.4 bits (83), Expect = 0.025, Method: Composition-based stats. Identities = 7/27 (25%), Positives = 11/27 (40%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMG 40 G +P G + TG + + P G Sbjct: 13 GLVPRGSHMASMTGGQQMGRGKRPKPG 39 >5J7Z-A nrPDB Length = 500 Score = 36.4 bits (83), Expect = 0.025, Method: Composition-based stats. Identities = 6/24 (25%), Positives = 10/24 (41%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDP 37 G +P G + TG + + P Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSAP 36 >5HXY-A nrPDB Length = 317 Score = 36.4 bits (83), Expect = 0.026, Method: Composition-based stats. Identities = 6/25 (24%), Positives = 11/25 (44%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPS 38 G +P G + TG + + P+ Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSMPA 37 >5HK8-A nrPDB Length = 298 Score = 36.4 bits (83), Expect = 0.026, Method: Composition-based stats. Identities = 5/24 (20%), Positives = 10/24 (41%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDP 37 G +P G + TG + + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSEF 36 >3PLN-A nrPDB Length = 424 Score = 36.4 bits (83), Expect = 0.026, Method: Composition-based stats. Identities = 5/24 (20%), Positives = 10/24 (41%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDP 37 G +P G + TG + + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSEF 36 >3NC3-A nrPDB Length = 441 Score = 36.4 bits (83), Expect = 0.026, Method: Composition-based stats. Identities = 5/24 (20%), Positives = 10/24 (41%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDP 37 G +P G + TG + + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSEF 36 >2UXN-B nrPDB Length = 235 Score = 36.4 bits (83), Expect = 0.026, Method: Composition-based stats. Identities = 5/24 (20%), Positives = 10/24 (41%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDP 37 G +P G + TG + + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSEF 36 >5Z9R-A nrPDB Length = 281 Score = 36.0 bits (82), Expect = 0.026, Method: Composition-based stats. Identities = 5/24 (20%), Positives = 10/24 (41%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDP 37 G +P G + TG + + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSEF 36 >5A2B-A nrPDB Length = 497 Score = 36.0 bits (82), Expect = 0.027, Method: Composition-based stats. Identities = 22/137 (16%), Positives = 40/137 (29%), Gaps = 16/137 (11%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLNEEQKEFQKVAF--------DFAAREMAPNM- 64 G +P G + TG + + +E+ F V D+ P Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSKTERTWQDERIYFIMVDRFNNGNPKNDYEVDVHDPKAY 72 Query: 65 AEWDQKELFPVDVMRKAAQLGFGGVYI----QTDVGGS-GLSRLDTSVIFEALATGCTST 119 D + + + ++GF +++ + GG G D + E T Sbjct: 73 HGGDLQGIIDK--LDYIKEMGFTAIWLTPIFANEKGGYHGYWIEDFYKVEEHFGTLDDFK 130 Query: 120 TAYISIHNMCAWMIDSF 136 H +I F Sbjct: 131 RLVKEAHKRDMKVILDF 147 >5GV1-A nrPDB Length = 322 Score = 36.0 bits (82), Expect = 0.029, Method: Composition-based stats. Identities = 5/24 (20%), Positives = 10/24 (41%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDP 37 G +P G + TG + + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSEF 36 >3L8A-A nrPDB Length = 421 Score = 36.0 bits (82), Expect = 0.029, Method: Composition-based stats. Identities = 10/70 (14%), Positives = 24/70 (34%), Gaps = 2/70 (2%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKEL- 72 G +P G + TG + + + + + E P + + ++ Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSMGRYDFTTRPDRLNQFTYKWKTSENNPELLQMWVADMD 72 Query: 73 -FPVDVMRKA 81 PV +++A Sbjct: 73 FLPVPEIKEA 82 >4ZCK-A nrPDB Length = 332 Score = 36.0 bits (82), Expect = 0.030, Method: Composition-based stats. Identities = 7/29 (24%), Positives = 11/29 (37%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLN 42 G +P G + TG + + SM Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSTVSMFFC 41 >3DEZ-A nrPDB Length = 243 Score = 36.0 bits (82), Expect = 0.031, Method: Composition-based stats. Identities = 23/179 (12%), Positives = 47/179 (26%), Gaps = 29/179 (16%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKE-- 71 G +P G + TG + + SM L ++ + D A + P Sbjct: 13 GLVPRGSHMASMTGGQQMGRG---SMTLAKD---IARDLLDIKAVYLKPEEPFTWASGIK 66 Query: 72 ---------LFPVDVMRKAAQLGFGGVYIQTDV-------GGSGLSRLDTSVIFEALATG 115 R + GF I+ G + ++I + + Sbjct: 67 SPIYTDNRITLSYPETRTLIENGFV-ETIKEAFPEVEVIAGTATAGIPHGAIIADKMNLP 125 Query: 116 CTSTTAYISIHNMCAWMIDSFGNEEQRHKFCPPLCT--MEKFASYCLTEPGSGSDAASL 172 + H I+ + Q+ L + + + G+D + Sbjct: 126 LAYIRSKPKDHG-AGNQIEGRVTKGQKMVIIEDLISTGGSVLDAVAAAQRE-GADVLGV 182 >5CTQ-A nrPDB Length = 561 Score = 36.0 bits (82), Expect = 0.032, Method: Composition-based stats. Identities = 5/25 (20%), Positives = 10/25 (40%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPS 38 G +P G + TG + + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSEFE 37 >4ABN-A nrPDB Length = 474 Score = 35.7 bits (81), Expect = 0.034, Method: Composition-based stats. Identities = 9/34 (26%), Positives = 16/34 (47%), Gaps = 3/34 (8%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLNEEQKE 47 G +P G + TG + + SM +EE++ Sbjct: 13 GLVPRGSHMASMTGGQQMGRG---SMMADEEEEA 43 >4Y12-A nrPDB Length = 375 Score = 35.7 bits (81), Expect = 0.036, Method: Composition-based stats. Identities = 5/25 (20%), Positives = 10/25 (40%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPS 38 G +P G + TG + + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSEFE 37 >3OIX-A nrPDB Length = 345 Score = 35.7 bits (81), Expect = 0.036, Method: Composition-based stats. Identities = 6/29 (20%), Positives = 10/29 (34%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLN 42 G +P G + TG + + S Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSMVSTHTT 41 >5EX6-C nrPDB Length = 434 Score = 35.7 bits (81), Expect = 0.038, Method: Composition-based stats. Identities = 10/58 (17%), Positives = 18/58 (31%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKE 71 G +P G + TG + + + G + + FD A A + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSEFMSGDDRPPIHTLRQGFDPADELRAAGELTRVRLG 70 >5ZBB-B nrPDB Length = 188 Score = 35.7 bits (81), Expect = 0.039, Method: Composition-based stats. Identities = 6/28 (21%), Positives = 11/28 (39%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGL 41 G +P G + TG + + + L Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSMSVVSL 40 >4U5I-A nrPDB Length = 403 Score = 35.7 bits (81), Expect = 0.041, Method: Composition-based stats. Identities = 13/90 (14%), Positives = 26/90 (28%), Gaps = 5/90 (5%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLNEEQKEFQKVA-----FDFAAREMAPNMAEWD 68 G +P G + TG + + E +++ Sbjct: 13 GLVPRGSHMASMTGGQQMGRIEGREFSSPEALAAYREAIGAGSSNPTPTPTWTSTPPSSS 72 Query: 69 QKELFPVDVMRKAAQLGFGGVYIQTDVGGS 98 K + P +++RK G ++ GS Sbjct: 73 PKAVDPFEMVRKMGMGTNLGNTLEAPYEGS 102 >4N8K-A nrPDB Length = 476 Score = 35.7 bits (81), Expect = 0.043, Method: Composition-based stats. Identities = 5/24 (20%), Positives = 10/24 (41%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDP 37 G +P G + TG + + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSEF 36 >4E1Q-A nrPDB Length = 207 Score = 35.3 bits (80), Expect = 0.047, Method: Composition-based stats. Identities = 5/24 (20%), Positives = 10/24 (41%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDP 37 G +P G + TG + + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSEF 36 >4J0Q-A nrPDB Length = 433 Score = 35.3 bits (80), Expect = 0.049, Method: Composition-based stats. Identities = 5/24 (20%), Positives = 10/24 (41%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDP 37 G +P G + TG + + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSEF 36 >3QAU-A nrPDB Length = 458 Score = 35.3 bits (80), Expect = 0.051, Method: Composition-based stats. Identities = 13/72 (18%), Positives = 27/72 (37%), Gaps = 2/72 (2%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLNEEQKEFQKVAFDF-AAREMAPNM-AEWDQKE 71 G +P G + TG + + +K +Q+ A ++P A ++ E Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSMKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDE 72 Query: 72 LFPVDVMRKAAQ 83 V V + ++ Sbjct: 73 QMSVTVADQLSE 84 >5K52-A nrPDB Length = 265 Score = 35.3 bits (80), Expect = 0.053, Method: Composition-based stats. Identities = 5/24 (20%), Positives = 10/24 (41%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDP 37 G +P G + TG + + + Sbjct: 9 GLVPRGSHMASMTGGQQMGRGSEF 32 >4WTS-A nrPDB Length = 298 Score = 35.3 bits (80), Expect = 0.054, Method: Composition-based stats. Identities = 7/29 (24%), Positives = 12/29 (41%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLN 42 G +P G + TG + + G+N Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSQTFYGIN 41 >3RPL-B nrPDB Length = 379 Score = 35.3 bits (80), Expect = 0.057, Method: Composition-based stats. Identities = 8/29 (27%), Positives = 15/29 (51%), Gaps = 1/29 (3%) Query: 14 GCLPGGLRVLVQTGHRSLTSC-IDPSMGL 41 G +P G + TG + + +D ++GL Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSVDSTLGL 41 >5JRE-A nrPDB Length = 219 Score = 34.9 bits (79), Expect = 0.059, Method: Composition-based stats. Identities = 10/49 (20%), Positives = 22/49 (44%), Gaps = 2/49 (4%) Query: 14 GCLPGGLRVLVQTGHRSLTSCID-PSMG-LNEEQKEFQKVAFDFAAREM 60 G +P G + TG + + P++ L EE ++ ++ + R + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSMLPNLDNLKEEYQKLEEKKQEIVDRSI 61 >4MSX-A nrPDB Length = 482 Score = 34.9 bits (79), Expect = 0.065, Method: Composition-based stats. Identities = 10/63 (15%), Positives = 25/63 (39%), Gaps = 3/63 (4%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELF 73 G +P G + TG + + DP M ++ +++ + A +++ + E Sbjct: 13 GLVPRGSHMASMTGGQQMGR--DP-MEVDNKRRHSEDELKQEAVKKIKSQEPNYAYLETV 69 Query: 74 PVD 76 + Sbjct: 70 VRE 72 >5J32-A nrPDB Length = 403 Score = 34.9 bits (79), Expect = 0.070, Method: Composition-based stats. Identities = 5/24 (20%), Positives = 10/24 (41%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDP 37 G +P G + TG + + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSEF 36 >4X9L-A nrPDB Length = 250 Score = 34.9 bits (79), Expect = 0.071, Method: Composition-based stats. Identities = 6/25 (24%), Positives = 10/25 (40%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPS 38 G +P G + TG + + S Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSMAS 37 >3QLL-A nrPDB Length = 316 Score = 34.9 bits (79), Expect = 0.071, Method: Composition-based stats. Identities = 7/33 (21%), Positives = 13/33 (39%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLNEEQK 46 G +P G + TG + + + L+ Q Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSEFMSNLDTYQT 45 >4M02-A nrPDB Length = 204 Score = 34.9 bits (79), Expect = 0.075, Method: Composition-based stats. Identities = 5/26 (19%), Positives = 9/26 (34%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSM 39 G +P G + TG + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSSAVT 38 >3K3P-A nrPDB Length = 383 Score = 34.9 bits (79), Expect = 0.075, Method: Composition-based stats. Identities = 6/28 (21%), Positives = 10/28 (35%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGL 41 G +P G + TG + + L Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSMSKETL 40 >3L87-A nrPDB Length = 238 Score = 34.5 bits (78), Expect = 0.085, Method: Composition-based stats. Identities = 9/63 (14%), Positives = 19/63 (30%), Gaps = 10/63 (15%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPS----------MGLNEEQKEFQKVAFDFAAREMAPN 63 G +P G + TG + + + + +N+ +E A P Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSMSAIKTITKASHLIDMNDIIREGHPTLRAVAQDVTFPL 72 Query: 64 MAE 66 + Sbjct: 73 NED 75 >5JZV-A nrPDB Length = 206 Score = 34.5 bits (78), Expect = 0.086, Method: Composition-based stats. Identities = 7/31 (22%), Positives = 13/31 (41%), Gaps = 2/31 (6%) Query: 14 GCLPGGLRVLVQTGHRSLTSCID--PSMGLN 42 G +P G + TG + + P++ L Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSMLLPNILLT 43 >6O09-C nrPDB Length = 312 Score = 34.5 bits (78), Expect = 0.092, Method: Composition-based stats. Identities = 5/22 (22%), Positives = 9/22 (40%) Query: 14 GCLPGGLRVLVQTGHRSLTSCI 35 G +P G + TG + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGS 34 >5XTP-A nrPDB Length = 293 Score = 34.5 bits (78), Expect = 0.092, Method: Composition-based stats. Identities = 5/22 (22%), Positives = 9/22 (40%) Query: 14 GCLPGGLRVLVQTGHRSLTSCI 35 G +P G + TG + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGS 34 >4M46-A nrPDB Length = 581 Score = 34.5 bits (78), Expect = 0.092, Method: Composition-based stats. Identities = 5/22 (22%), Positives = 9/22 (40%) Query: 14 GCLPGGLRVLVQTGHRSLTSCI 35 G +P G + TG + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGS 34 >4M00-A nrPDB Length = 541 Score = 34.5 bits (78), Expect = 0.092, Method: Composition-based stats. Identities = 5/22 (22%), Positives = 9/22 (40%) Query: 14 GCLPGGLRVLVQTGHRSLTSCI 35 G +P G + TG + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGS 34 >4IG7-A nrPDB Length = 343 Score = 34.5 bits (78), Expect = 0.092, Method: Composition-based stats. Identities = 5/22 (22%), Positives = 9/22 (40%) Query: 14 GCLPGGLRVLVQTGHRSLTSCI 35 G +P G + TG + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGS 34 >4HG5-A nrPDB Length = 341 Score = 34.5 bits (78), Expect = 0.092, Method: Composition-based stats. Identities = 5/22 (22%), Positives = 9/22 (40%) Query: 14 GCLPGGLRVLVQTGHRSLTSCI 35 G +P G + TG + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGS 34 >4HBK-A nrPDB Length = 344 Score = 34.5 bits (78), Expect = 0.092, Method: Composition-based stats. Identities = 5/22 (22%), Positives = 9/22 (40%) Query: 14 GCLPGGLRVLVQTGHRSLTSCI 35 G +P G + TG + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGS 34 >3LEH-A nrPDB Length = 425 Score = 34.5 bits (78), Expect = 0.092, Method: Composition-based stats. Identities = 5/22 (22%), Positives = 9/22 (40%) Query: 14 GCLPGGLRVLVQTGHRSLTSCI 35 G +P G + TG + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGS 34 >3L9D-A nrPDB Length = 255 Score = 34.5 bits (78), Expect = 0.092, Method: Composition-based stats. Identities = 5/22 (22%), Positives = 9/22 (40%) Query: 14 GCLPGGLRVLVQTGHRSLTSCI 35 G +P G + TG + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGS 34 >3L9C-A nrPDB Length = 259 Score = 34.5 bits (78), Expect = 0.092, Method: Composition-based stats. Identities = 5/22 (22%), Positives = 9/22 (40%) Query: 14 GCLPGGLRVLVQTGHRSLTSCI 35 G +P G + TG + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGS 34 >3L7R-A nrPDB Length = 779 Score = 34.5 bits (78), Expect = 0.092, Method: Composition-based stats. Identities = 5/22 (22%), Positives = 9/22 (40%) Query: 14 GCLPGGLRVLVQTGHRSLTSCI 35 G +P G + TG + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGS 34 >6GII-A nrPDB Length = 479 Score = 34.5 bits (78), Expect = 0.098, Method: Composition-based stats. Identities = 7/40 (17%), Positives = 14/40 (35%), Gaps = 8/40 (20%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLNEEQKEFQKVAF 53 G +P G + TG + + + E ++ A Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSM--------ETELKETAR 44 Score = 28.3 bits (62), Expect = 6.8, Method: Composition-based stats. Identities = 26/121 (21%), Positives = 41/121 (33%), Gaps = 15/121 (12%) Query: 232 KEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGGRINIASCSLGAAHAS 291 GW + TR V E +PV G L+ V N + Sbjct: 352 NGPVAGWRRRTTREVEVEGVRLPV-------GANILMVVASANHDSAHFDDPEF------ 398 Query: 292 VILTRDHLNVRKQFGEPLASNQYLQFTLADMATRLVAARLMVRNAAVALQEERKDAVALC 351 + R + + FG ++Q L L M +++ L R + L E+R D + Sbjct: 399 FDIGRSNASEHLNFG--YGAHQCLGRNLGRMEMQIMIEELSRRLPHMRLAEQRFDYLHNV 456 Query: 352 S 352 S Sbjct: 457 S 457 >5C2O-A nrPDB Length = 184 Score = 34.5 bits (78), Expect = 0.098, Method: Composition-based stats. Identities = 5/22 (22%), Positives = 9/22 (40%) Query: 14 GCLPGGLRVLVQTGHRSLTSCI 35 G +P G + TG + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGS 34 >3SR7-A nrPDB Length = 365 Score = 34.5 bits (78), Expect = 0.098, Method: Composition-based stats. Identities = 5/22 (22%), Positives = 9/22 (40%) Query: 14 GCLPGGLRVLVQTGHRSLTSCI 35 G +P G + TG + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGS 34 >4XCH-A nrPDB Length = 194 Score = 34.1 bits (77), Expect = 0.10, Method: Composition-based stats. Identities = 5/22 (22%), Positives = 9/22 (40%) Query: 14 GCLPGGLRVLVQTGHRSLTSCI 35 G +P G + TG + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGS 34 >4B28-A nrPDB Length = 470 Score = 34.1 bits (77), Expect = 0.10, Method: Composition-based stats. Identities = 10/29 (34%), Positives = 13/29 (44%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLN 42 G +P G + H + T IDPS G Sbjct: 13 GLVPRGSHMASMNRHFNATRKIDPSRGAT 41 >3L86-A nrPDB Length = 279 Score = 34.1 bits (77), Expect = 0.11, Method: Composition-based stats. Identities = 5/22 (22%), Positives = 9/22 (40%) Query: 14 GCLPGGLRVLVQTGHRSLTSCI 35 G +P G + TG + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGS 34 >4NZZ-A nrPDB Length = 320 Score = 34.1 bits (77), Expect = 0.11, Method: Composition-based stats. Identities = 5/21 (23%), Positives = 9/21 (42%) Query: 14 GCLPGGLRVLVQTGHRSLTSC 34 G +P G + TG + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRG 33 >3P2M-A nrPDB Length = 330 Score = 34.1 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 9/32 (28%), Positives = 14/32 (43%), Gaps = 2/32 (6%) Query: 14 GCLPGGLRVLVQTGHRSLTSC--IDPSMGLNE 43 G +P G + TG + + D GL+E Sbjct: 13 GLVPRGSHMASMTGGQQMGRVLSDDELTGLDE 44 >3L7V-A nrPDB Length = 295 Score = 33.7 bits (76), Expect = 0.14, Method: Composition-based stats. Identities = 5/22 (22%), Positives = 9/22 (40%) Query: 14 GCLPGGLRVLVQTGHRSLTSCI 35 G +P G + TG + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGS 34 >3NIB-A nrPDB Length = 309 Score = 33.7 bits (76), Expect = 0.15, Method: Composition-based stats. Identities = 9/82 (10%), Positives = 19/82 (23%), Gaps = 1/82 (1%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLNEEQKEFQKV-AFDFAAREMAPNMAEWDQKEL 72 G +P G + TG + + + + A + + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSMNGIRWIASYPKAGNTWLRCMLAAYITGKAPQTWKDME 72 Query: 73 FPVDVMRKAAQLGFGGVYIQTD 94 + LG T Sbjct: 73 TVSLELEGMLHLGDMPPTEPTK 94 >6ERD-A nrPDB Length = 211 Score = 33.7 bits (76), Expect = 0.15, Method: Composition-based stats. Identities = 6/25 (24%), Positives = 11/25 (44%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPS 38 G +P G + TG + + + S Sbjct: 13 GLVPRGSHMASMTGGQQMGRDPNSS 37 >4XWN-A nrPDB Length = 681 Score = 33.7 bits (76), Expect = 0.15, Method: Composition-based stats. Identities = 5/27 (18%), Positives = 9/27 (33%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMG 40 G +P G + TG + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRIEGREFA 39 >3UDT-A nrPDB Length = 493 Score = 33.7 bits (76), Expect = 0.16, Method: Composition-based stats. Identities = 5/20 (25%), Positives = 9/20 (45%) Query: 14 GCLPGGLRVLVQTGHRSLTS 33 G +P G + TG + + Sbjct: 13 GLVPRGSHMASMTGGQQMGR 32 >2NT8-A nrPDB Length = 223 Score = 33.7 bits (76), Expect = 0.16, Method: Composition-based stats. Identities = 5/20 (25%), Positives = 9/20 (45%) Query: 14 GCLPGGLRVLVQTGHRSLTS 33 G +P G + TG + + Sbjct: 13 GLVPRGSHMASMTGGQQMGR 32 >4ETN-A nrPDB Length = 184 Score = 33.4 bits (75), Expect = 0.17, Method: Composition-based stats. Identities = 5/22 (22%), Positives = 9/22 (40%) Query: 14 GCLPGGLRVLVQTGHRSLTSCI 35 G +P G + TG + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGS 34 >5JZX-A nrPDB Length = 405 Score = 33.4 bits (75), Expect = 0.18, Method: Composition-based stats. Identities = 5/24 (20%), Positives = 10/24 (41%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDP 37 G +P G + TG + + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGSEF 36 >4QPJ-C nrPDB Length = 152 Score = 33.4 bits (75), Expect = 0.18, Method: Composition-based stats. Identities = 5/22 (22%), Positives = 9/22 (40%) Query: 14 GCLPGGLRVLVQTGHRSLTSCI 35 G +P G + TG + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGS 34 >3W53-A nrPDB Length = 506 Score = 33.4 bits (75), Expect = 0.19, Method: Composition-based stats. Identities = 5/22 (22%), Positives = 9/22 (40%) Query: 14 GCLPGGLRVLVQTGHRSLTSCI 35 G +P G + TG + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGS 34 >4EGS-A nrPDB Length = 180 Score = 33.4 bits (75), Expect = 0.19, Method: Composition-based stats. Identities = 5/22 (22%), Positives = 9/22 (40%) Query: 14 GCLPGGLRVLVQTGHRSLTSCI 35 G +P G + TG + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGS 34 >5XCN-X nrPDB Length = 350 Score = 33.4 bits (75), Expect = 0.22, Method: Composition-based stats. Identities = 5/22 (22%), Positives = 9/22 (40%) Query: 14 GCLPGGLRVLVQTGHRSLTSCI 35 G +P G + TG + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGS 34 >3BGK-A nrPDB Length = 311 Score = 33.0 bits (74), Expect = 0.24, Method: Composition-based stats. Identities = 5/22 (22%), Positives = 9/22 (40%) Query: 14 GCLPGGLRVLVQTGHRSLTSCI 35 G +P G + TG + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGS 34 >3LA8-A nrPDB Length = 303 Score = 33.0 bits (74), Expect = 0.26, Method: Composition-based stats. Identities = 5/22 (22%), Positives = 9/22 (40%) Query: 14 GCLPGGLRVLVQTGHRSLTSCI 35 G +P G + TG + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGS 34 >3MGC-A nrPDB Length = 319 Score = 33.0 bits (74), Expect = 0.27, Method: Composition-based stats. Identities = 5/22 (22%), Positives = 9/22 (40%) Query: 14 GCLPGGLRVLVQTGHRSLTSCI 35 G +P G + TG + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGS 34 >5LW6-A nrPDB Length = 255 Score = 33.0 bits (74), Expect = 0.28, Method: Composition-based stats. Identities = 7/41 (17%), Positives = 15/41 (36%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLNEEQKEFQKVAFD 54 G +P G + TG ++ + +G +K + Sbjct: 13 GLVPRGSHMASMTGGNNMGAGSSKIIGPKYRKKRLTDALKE 53 >2LEC-A nrPDB Length = 135 Score = 32.6 bits (73), Expect = 0.30, Method: Composition-based stats. Identities = 5/22 (22%), Positives = 9/22 (40%) Query: 14 GCLPGGLRVLVQTGHRSLTSCI 35 G +P G + TG + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGS 34 >3GZ3-A nrPDB Length = 354 Score = 32.6 bits (73), Expect = 0.33, Method: Composition-based stats. Identities = 24/153 (15%), Positives = 44/153 (28%), Gaps = 37/153 (24%) Query: 14 GCLPGGLRVLVQTGHRSLTSCI-------------DPSM-------GLNEEQKEFQKVAF 53 G +P G + TG + + +P M EE + A Sbjct: 13 GLVPAGSHMASMTGGQQMGRGSMSLQVNLLNNTFANPFMNAAGVMCTTTEELVAMTESAS 72 Query: 54 -DFAAREMAPNMAEWD---QKELFPVDVMRKAA------QLGFGGVYIQTDVGG------ 97 ++ P + E + + + P+ + Q D G Sbjct: 73 GSLVSKSCTPALREGNPTPRYQALPLGSINSMGLPNNGFDFYLAYAAEQHDYGKKPLFLS 132 Query: 98 -SGLSRLDTSVIFEALATGCTSTTAYISIHNMC 129 SGLS + + + LA T + ++ C Sbjct: 133 MSGLSMRENVEMCKRLAAVATEKGVILELNLSC 165 >4QPJ-A nrPDB Length = 243 Score = 32.6 bits (73), Expect = 0.34, Method: Composition-based stats. Identities = 5/22 (22%), Positives = 9/22 (40%) Query: 14 GCLPGGLRVLVQTGHRSLTSCI 35 G +P G + TG + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGS 34 >3QWY-A nrPDB Length = 308 Score = 32.6 bits (73), Expect = 0.36, Method: Composition-based stats. Identities = 6/19 (31%), Positives = 10/19 (52%) Query: 14 GCLPGGLRVLVQTGHRSLT 32 G +P G + TG + +T Sbjct: 13 GLVPRGSHMASMTGGQQMT 31 >4LIV-A nrPDB Length = 407 Score = 32.6 bits (73), Expect = 0.37, Method: Composition-based stats. Identities = 5/22 (22%), Positives = 8/22 (36%) Query: 14 GCLPGGLRVLVQTGHRSLTSCI 35 G +P G + TG + Sbjct: 13 GLVPRGSHMASMTGGEEMGRGS 34 >2WST-A nrPDB Length = 208 Score = 31.8 bits (71), Expect = 0.53, Method: Composition-based stats. Identities = 6/30 (20%), Positives = 12/30 (40%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLNE 43 G +P G + TG + + P++ Sbjct: 13 GLVPRGSHMASMTGGQQGRILVYPTLWTGP 42 >4NV8-A nrPDB Length = 312 Score = 31.8 bits (71), Expect = 0.58, Method: Composition-based stats. Identities = 7/33 (21%), Positives = 12/33 (36%), Gaps = 3/33 (9%) Query: 14 GCLPGGLRVLVQTGHRSLTSC---IDPSMGLNE 43 G +P G + TG + + P L+ Sbjct: 13 GLVPRGSHMASNTGGQQMGRGSMNDAPPFDLDA 45 >4WZH-A nrPDB Length = 347 Score = 31.4 bits (70), Expect = 0.64, Method: Composition-based stats. Identities = 5/22 (22%), Positives = 8/22 (36%) Query: 14 GCLPGGLRVLVQTGHRSLTSCI 35 G +P G + TG + Sbjct: 13 GLVPRGSHMASMTGGGQMGRGS 34 >3UL6-A nrPDB Length = 139 Score = 31.4 bits (70), Expect = 0.64, Method: Composition-based stats. Identities = 5/23 (21%), Positives = 10/23 (43%) Query: 14 GCLPGGLRVLVQTGHRSLTSCID 36 G +P G + TG + + + Sbjct: 13 GLVPRGSHMASMTGGQQMGRGMA 35 >3CNC-A nrPDB Length = 220 Score = 31.0 bits (69), Expect = 0.85, Method: Composition-based stats. Identities = 6/30 (20%), Positives = 10/30 (33%) Query: 19 GLRVLVQTGHRSLTSCIDPSMGLNEEQKEF 48 G + TG + + D S + E Sbjct: 1 GSHMASMTGGQQMGRGSDSSNAITIENNTL 30 >3RK6-A nrPDB Length = 234 Score = 31.0 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 9/47 (19%), Positives = 14/47 (29%), Gaps = 7/47 (14%) Query: 19 GLRVLVQTGHRSLTS-------CIDPSMGLNEEQKEFQKVAFDFAAR 58 G + TG + + D L E+ F+ FA Sbjct: 1 GSHMASMTGGQQMGRGSTLSEYVQDFLNHLTEQPGSFETEIEQFAET 47 >4G32-A nrPDB Length = 688 Score = 30.7 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 10/55 (18%), Positives = 20/55 (36%), Gaps = 6/55 (10%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLNEEQKEFQKVAFDFAAREMAPNMAEWD 68 G +P G + + S P L EQ+ + + P++ ++D Sbjct: 13 GLVPRGSHMANDSIFFS------PLKYLGAEQQRSIDASRSLLDNLIPPSLPQYD 61 >2YCJ-A nrPDB Length = 271 Score = 30.7 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 11/46 (23%), Positives = 19/46 (41%), Gaps = 1/46 (2%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMG-LNEEQKEFQKVAFDFAAR 58 G +P G + + G R D LN++ + Q+ A A + Sbjct: 1 GLVPRGSHMFIMIGERINGMFKDIREAILNKDPRPIQEWARRQAEK 46 >3DR5-A nrPDB Length = 221 Score = 30.7 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 26/142 (18%), Positives = 46/142 (32%), Gaps = 21/142 (14%) Query: 147 PPLCTMEKFASYCLTEPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCR 206 P T + + T G+GS A +T A YILNG +D + C Sbjct: 37 PDEMTGQLLTTLAATTNGNGSTGAIAITPAAGLVGLYILNG---------LADNTTLTCI 87 Query: 207 TGGPGP-KGISCIVVEKG-TPG---LSFGKKEKKVGWNSQPTRAVIFEDCA-------VP 254 + + E G +P + + + + ++F + V Sbjct: 88 DPESEHQRQAKALFREAGYSPSRVRFLLSRPLDVMSRLANDSYQLVFGQVSPMDLKALVD 147 Query: 255 VANRIGSEGQGFLIAVRGLNGG 276 A + G ++A L+G Sbjct: 148 AAWPLLRRGGALVLADALLDGT 169 >4LGZ-A nrPDB Length = 563 Score = 29.9 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 13/53 (24%), Positives = 19/53 (35%), Gaps = 4/53 (7%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGL---NEEQKEFQKVAFDF-AAREMAP 62 G +P G +L SL +P + + E+ QK D E P Sbjct: 13 GLVPRGSHMLRWKHTSSLKVANEPILAFSQGSPERDALQKALKDLKGQTEAIP 65 >6DGE-A nrPDB Length = 308 Score = 29.9 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 20/110 (18%), Positives = 35/110 (31%), Gaps = 10/110 (9%) Query: 14 GCLPGGLRVLVQTG-HRSLTSCIDPSMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKEL 72 G +P G + G + + + A A E ++A +++ Sbjct: 13 GLVPRGSHMASMAGLGHPAAFGRATHAVVRALPESLGQHALRSAKGEEV-DVARAERQHQ 71 Query: 73 FPVDVMRKAAQLGFGGVYIQTDVGGSGLSRLDTSVIFEALATGCTSTTAY 122 V V+ ++LG V + D L V E +A C T Sbjct: 72 LYVGVLG--SKLGLQVVELPAD------ESLPDCVFVEDVAVVCEETALI 113 >3VQX-A nrPDB Length = 291 Score = 29.9 bits (66), Expect = 2.0, Method: Composition-based stats. Identities = 12/97 (12%), Positives = 27/97 (27%), Gaps = 15/97 (15%) Query: 14 GCLPGGLRVLVQTGHRS---------LTSCIDPSMGLNEEQKEFQKVAFDFAAREMAPNM 64 G +P G + L + S+ + +E + +++ Sbjct: 13 GLVPRGSHMASAPALTKSQTDRLEVLLNPKDEISLNSGKPFRELESELLSRRKKDLQQIY 72 Query: 65 AEWDQK--ELFPVDVMRKAAQLGFGG----VYIQTDV 95 AE + ++ R GF + I + Sbjct: 73 AEERENYLGKLEREITRFFVDRGFLEIKSPILIPLEY 109 >4GAX-A nrPDB Length = 563 Score = 29.9 bits (66), Expect = 2.1, Method: Composition-based stats. Identities = 8/27 (29%), Positives = 12/27 (44%), Gaps = 3/27 (11%) Query: 19 GLRVLVQTGHRSLTSCIDPSMGLNEEQ 45 G + TG + + SM L EE+ Sbjct: 1 GSHMASMTGGQQMGRG---SMSLTEEK 24 >5M07-A nrPDB Length = 276 Score = 29.9 bits (66), Expect = 2.3, Method: Composition-based stats. Identities = 13/97 (13%), Positives = 28/97 (28%), Gaps = 29/97 (29%) Query: 14 GCLPGGLRVLVQTG-----------------------------HRSLTSCIDPSMGLNEE 44 G +P G + + +G + P+M ++E Sbjct: 13 GLVPRGSHMALASGVTFAGYTVVRMLGASAMGEVYLVQHPGFPGWQALKVLSPAMAADDE 72 Query: 45 QKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKA 81 + + + AAR P++ E + F + Sbjct: 73 FRRRFQRETEVAARLFHPHILEVHDRGEFDGQLWIAM 109 >5YBH-A nrPDB Length = 368 Score = 29.9 bits (66), Expect = 2.3, Method: Composition-based stats. Identities = 7/30 (23%), Positives = 14/30 (46%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLNE 43 G +P G + Q G L + ++P + + Sbjct: 13 GLVPRGSHMHTQVGRGLLGAVVNPLGEVTD 42 >1R20-D nrPDB Length = 265 Score = 29.9 bits (66), Expect = 2.4, Method: Composition-based stats. Identities = 7/51 (13%), Positives = 14/51 (27%) Query: 19 GLRVLVQTGHRSLTSCIDPSMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQ 69 G + TG + + L QK + P+ + + Sbjct: 1 GSHMASMTGGQQMGRDPKNVPPLTANQKSLIARLVYYQEGYEQPSEEDLKR 51 >4QNW-A nrPDB Length = 392 Score = 29.5 bits (65), Expect = 2.6, Method: Composition-based stats. Identities = 16/67 (23%), Positives = 29/67 (43%), Gaps = 8/67 (11%) Query: 319 LADMATRLVAARLMVRNAA----VALQEERKDAVALCSMAKLFATDECFAICNQALQMHG 374 LADM + ++ + V ++E + +A + A A + F +++HG Sbjct: 119 LADMKDLISSSAVPVEEKGPLPRALTEDEIQQCIADFAQAARNAINAGF----DGVEIHG 174 Query: 375 GYGYLKD 381 GYL D Sbjct: 175 ANGYLID 181 >6J5G-A nrPDB Length = 407 Score = 29.5 bits (65), Expect = 2.9, Method: Composition-based stats. Identities = 10/58 (17%), Positives = 25/58 (43%), Gaps = 1/58 (1%) Query: 162 EPGSGSDAASLLTSAKKQGDHYILNGSKAFISGAGESDIYVVMCRTGGPGPKGISCIV 219 EP +G A+ T + ++ + ++ K ++ D+ + +CR + I+ Sbjct: 144 EPHTGDYVAANETHSGRKTASFTISSEKTILTMGEYGDVSL-LCRVASGVDLAQTVIL 200 >4IXL-A nrPDB Length = 244 Score = 29.5 bits (65), Expect = 3.2, Method: Composition-based stats. Identities = 4/23 (17%), Positives = 8/23 (34%) Query: 14 GCLPGGLRVLVQTGHRSLTSCID 36 G + G + TG + + Sbjct: 13 GLVFRGSHMASMTGGQQMGRGSQ 35 >5LOW-D nrPDB Length = 95 Score = 29.1 bits (64), Expect = 3.2, Method: Composition-based stats. Identities = 8/42 (19%), Positives = 16/42 (38%), Gaps = 3/42 (7%) Query: 19 GLRVLVQTGHRSLTSCIDPSMGLNEEQKEFQKVAFDFAAREM 60 G + TG + + + + E +E Q+ A A + Sbjct: 1 GSHMASMTGGQQMGRGSEF---MRNELEEMQRRADQLADESL 39 >4M4V-A nrPDB Length = 422 Score = 29.1 bits (64), Expect = 3.2, Method: Composition-based stats. Identities = 18/122 (14%), Positives = 37/122 (30%), Gaps = 5/122 (4%) Query: 192 ISGAGESDIYVVMCRTGGPGPKGISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDC 251 I + + R G G +G +V+ L + + G+ + Sbjct: 244 IGRGAPGNRTWSVQRLSGAGAEG---TIVQTPDGKLYRNDRPSQKGYRMVARGTLEGFGA 300 Query: 252 AVPVANRIGSEGQGFLIAVRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQF--GEPL 309 P A QG ++ R + + G + ++ + + K+F G L Sbjct: 301 FAPDAGLPDPACQGSVLRYNSDAPARTIFLNSASGTSRRAMRVRISYDADAKKFNYGRKL 360 Query: 310 AS 311 Sbjct: 361 ED 362 >1VHE-A nrPDB Length = 373 Score = 29.1 bits (64), Expect = 3.6, Method: Composition-based stats. Identities = 20/108 (18%), Positives = 39/108 (36%), Gaps = 13/108 (12%) Query: 205 CRTGGPGPKGISCIVVEK----GTPGLSFGKKEKKVG-------WNSQPTRAVIFEDCAV 253 +T + V+ TPG+S + + K+G +++ D V Sbjct: 223 AKTAAHTIQPDIAFGVDVGIAGDTPGISEKEAQSKMGKGPQIIVYDASMVSHKGLRDAVV 282 Query: 254 PVANRIGSEGQGFLIAVRGLNGGRINIASCSLGAAHASVILTRDHLNV 301 A G Q IA G + G I++ + G S+ + +++ Sbjct: 283 ATAEEAGIPYQFDAIAGGGTDSGAIHLTA--NGVPALSITIATRYIHT 328 >2Q3R-A nrPDB Length = 372 Score = 29.1 bits (64), Expect = 3.6, Method: Composition-based stats. Identities = 7/26 (26%), Positives = 10/26 (38%) Query: 356 LFATDECFAICNQALQMHGGYGYLKD 381 A +++HG GYL D Sbjct: 166 RLAARNAMEAGFDGVEIHGANGYLID 191 >5UIC-A nrPDB Length = 144 Score = 29.1 bits (64), Expect = 4.0, Method: Composition-based stats. Identities = 7/57 (12%), Positives = 22/57 (38%), Gaps = 2/57 (3%) Query: 19 GLRVLVQTGHRSLTSCIDPSMGLNEEQKEFQKVAFDFAARE--MAPNMAEWDQKELF 73 G + TG + + + + L E+ + + +E + +++ + + F Sbjct: 1 GSHMASMTGGQQMGRDPNMRILLAEDDLHLGEGLLEALQKEGLIVNLVSDGEAAQTF 57 >5W8P-A nrPDB Length = 370 Score = 29.1 bits (64), Expect = 4.1, Method: Composition-based stats. Identities = 17/65 (26%), Positives = 24/65 (36%), Gaps = 3/65 (4%) Query: 86 FGGVYIQTDVGGSGLSRLDTSVIFEALA---TGCTSTTAYISIHNMCAWMIDSFGNEEQR 142 G + VGG RL + E LA GCT S+H A++I+ E Sbjct: 303 LRGCPVPVVVGGITSDRLYPLRLQEELADLLPGCTGLRVVESVHGHDAFLIEFDAVSELV 362 Query: 143 HKFCP 147 + Sbjct: 363 RETLA 367 >6HX8-E nrPDB Length = 143 Score = 28.7 bits (63), Expect = 4.6, Method: Composition-based stats. Identities = 13/54 (24%), Positives = 27/54 (50%), Gaps = 3/54 (5%) Query: 30 SLTSCIDPSMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQ 83 SL DPS+ +++ E + + E+ ++AE + E +V++KA + Sbjct: 36 SLPRRRDPSLEEIQKKLEAAEERRKYQEAELLKHLAEKREHE---REVIQKAIE 86 >5XAF-E nrPDB Length = 189 Score = 28.7 bits (63), Expect = 4.6, Method: Composition-based stats. Identities = 13/54 (24%), Positives = 27/54 (50%), Gaps = 3/54 (5%) Query: 30 SLTSCIDPSMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQ 83 SL DPS+ +++ E + + E+ ++AE + E +V++KA + Sbjct: 82 SLPRRRDPSLEEIQKKLEAAEERRKYQEAELLKHLAEKREHE---REVIQKAIE 132 >1G29-1 nrPDB Length = 372 Score = 28.7 bits (63), Expect = 4.9, Method: Composition-based stats. Identities = 9/43 (20%), Positives = 14/43 (32%), Gaps = 4/43 (9%) Query: 236 VGWNSQPTRAVIFEDCAVPVANRIGSEGQGFLIAVRGLNGGRI 278 G + +F VP N + + + V L RI Sbjct: 287 FGIRPEDLYDAMFAQVRVPGENLV----RAVVEIVENLGSERI 325 >5YRZ-B nrPDB Length = 89 Score = 28.7 bits (63), Expect = 5.2, Method: Composition-based stats. Identities = 7/26 (26%), Positives = 12/26 (46%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSM 39 G +P G ++V +G +S M Sbjct: 13 GLVPRGSHMMVLSGGKSAMPMTQKEM 38 >6B1B-A nrPDB Length = 527 Score = 28.7 bits (63), Expect = 5.4, Method: Composition-based stats. Identities = 17/149 (11%), Positives = 45/149 (30%), Gaps = 25/149 (16%) Query: 136 FGNEEQRHK-FCPPLCTMEKFASYCLTEPGSGSDAASLLTS-----AKKQGD-HYILNGS 188 +G EQ + + + + ++ + P + +K+ D I++G+ Sbjct: 139 YGQFEQNARNWYTRIQETGLYFNHAIVNPPIDRHLPTDKVKDVYIKLEKETDAGIIVSGA 198 Query: 189 KAFISGAGESDIYVVMCRTGGPG---PKGISCIVVEKGTPGLSFGKK---EKKVGWNSQP 242 K + + + ++ + P V G+ + E G P Sbjct: 199 KVVATNSALTHYNMIGSGSDLGSGSDPDFALMFVAPMDADGVKLISRASYEMVAGATGSP 258 Query: 243 ------------TRAVIFEDCAVPVANRI 259 ++ ++ +P N + Sbjct: 259 YDYPLSSRFDENDAILVMDNVLIPWENVL 287 >2J08-A nrPDB Length = 420 Score = 28.3 bits (62), Expect = 5.8, Method: Composition-based stats. Identities = 12/73 (16%), Positives = 21/73 (28%), Gaps = 5/73 (6%) Query: 33 SCIDPSMGLNEE-QKEFQKVAFDFAAREMAPNMAEWDQKELFPVDVMRKAAQLGFGG--- 88 DP + L E ++ F ++ E D+ + + LG Sbjct: 166 PREDPGLPLPEPGEEAALAGLRAFLEAKLPRYAEERDRLDGEGGSRLSPYFALGVLSPRL 225 Query: 89 -VYIQTDVGGSGL 100 + GG G Sbjct: 226 AAWEAERRGGEGA 238 >6CHV-A nrPDB Length = 121 Score = 28.3 bits (62), Expect = 5.9, Method: Composition-based stats. Identities = 4/36 (11%), Positives = 11/36 (30%) Query: 19 GLRVLVQTGHRSLTSCIDPSMGLNEEQKEFQKVAFD 54 G + TG + + ++ + + D Sbjct: 1 GSHMASMTGGQQMGRGSMRQFKVSHPGEMIARDLED 36 >2GG4-A nrPDB Length = 455 Score = 28.3 bits (62), Expect = 6.0, Method: Composition-based stats. Identities = 7/33 (21%), Positives = 16/33 (48%), Gaps = 4/33 (12%) Query: 164 GSGSDAASLLTSAKKQGDHYILNGSKAFISGAG 196 +G ++ +K+GD +I++G + G Sbjct: 58 NTGKAMQAMGARIRKEGDTWIIDG----VGNGG 86 >4DBZ-A nrPDB Length = 281 Score = 28.3 bits (62), Expect = 6.1, Method: Composition-based stats. Identities = 10/73 (13%), Positives = 24/73 (32%), Gaps = 10/73 (13%) Query: 14 GCLPGGLRVLVQTGHRSLTSCIDPSMGLNEEQKEFQKVAFDFAAREMAPNMAEWDQKELF 73 G +P G + Q +L + +GL ++ ++ F + E Sbjct: 13 GLVPRGSHMATQDSEVALVTGATSGIGLEIARRLGKEGLRVFVCA----------RGEEG 62 Query: 74 PVDVMRKAAQLGF 86 +++ + G Sbjct: 63 LRTTLKELREAGV 75 >1ICQ-A nrPDB Length = 376 Score = 28.0 bits (61), Expect = 8.5, Method: Composition-based stats. Identities = 7/26 (26%), Positives = 11/26 (42%) Query: 356 LFATDECFAICNQALQMHGGYGYLKD 381 A +++HG +GYL D Sbjct: 170 RVAARNAIEAGFDGVEIHGAHGYLID 195 >5DU2-A nrPDB Length = 419 Score = 27.6 bits (60), Expect = 9.8, Method: Composition-based stats. Identities = 11/44 (25%), Positives = 18/44 (40%) Query: 254 PVANRIGSEGQGFLIAVRGLNGGRINIASCSLGAAHASVILTRD 297 P+A R+G G G ++ G R+ A L A++ Sbjct: 350 PMARRVGELGLGTVVPAAEFTGARLREAVEDLAGDRAALERVLR 393 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.148 0.408 Lambda K H 0.267 0.0453 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,112,597 Number of Sequences: 36641 Number of extensions: 733279 Number of successful extensions: 3451 Number of sequences better than 10.0: 230 Number of HSP's better than 10.0 without gapping: 252 Number of HSP's successfully gapped in prelim test: 50 Number of HSP's that attempted gapping in prelim test: 2738 Number of HSP's gapped (non-prelim): 324 length of query: 415 length of database: 10,336,785 effective HSP length: 100 effective length of query: 315 effective length of database: 6,672,685 effective search space: 2101895775 effective search space used: 2101895775 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 61 (28.0 bits)