BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9UK55 (444 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4AJU-A nrPDB 798 0.0 4AJT-A nrPDB 618 e-177 6EE5-A nrPDB 275 2e-74 3NE4-A nrPDB 214 8e-56 4Y40-A nrPDB 213 1e-55 5HGC-A nrPDB 211 4e-55 6HGE-B nrPDB 209 2e-54 2VDY-A nrPDB 199 2e-51 2OL2-A nrPDB 197 9e-51 3DY0-A nrPDB 190 1e-48 1JMJ-A nrPDB 182 3e-46 1YXA-A nrPDB 181 5e-46 1QMB-A nrPDB 177 1e-44 2XN5-A nrPDB 170 1e-42 3NDA-A nrPDB 167 7e-42 1BY7-A nrPDB 163 1e-40 1ATT-A nrPDB 158 4e-39 4DY0-A nrPDB 154 1e-37 5INW-A nrPDB 153 1e-37 2V95-A nrPDB 153 2e-37 1C5G-A nrPDB 153 2e-37 4GA7-A nrPDB 151 5e-37 4KDS-A nrPDB 150 8e-37 6F02-A nrPDB 150 1e-36 3LW2-A nrPDB 150 1e-36 4EB1-I nrPDB 149 2e-36 3OZQ-A nrPDB 146 2e-35 1UHG-A nrPDB 145 4e-35 1IMV-A nrPDB 141 6e-34 3F02-A nrPDB 140 1e-33 4P0F-A nrPDB 140 1e-33 2H4Q-A nrPDB 140 1e-33 2R9Y-A nrPDB 138 6e-33 6CJ7-A nrPDB 136 1e-32 1HLE-A nrPDB 134 9e-32 4DTE-A nrPDB 133 1e-31 2H4P-A nrPDB 133 1e-31 6F4U-A nrPDB 130 8e-31 4ZK0-A nrPDB 129 2e-30 3PZF-A nrPDB 126 2e-29 3ZHA-A nrPDB 119 2e-27 1SEK-A nrPDB 119 2e-27 2OAY-A nrPDB 118 4e-27 1K9O-I nrPDB 118 5e-27 1JJO-C nrPDB 118 6e-27 5NCS-A nrPDB 115 3e-26 6BJ5-B nrPDB 112 4e-25 1C8O-A nrPDB 110 1e-24 3LE2-A nrPDB 109 3e-24 1XQJ-A nrPDB 108 5e-24 1M93-B nrPDB 101 6e-22 2PEF-A nrPDB 101 6e-22 3STO-A nrPDB 99 4e-21 1SNG-A nrPDB 97 1e-20 5NCU-A nrPDB 95 6e-20 2WXX-A nrPDB 87 2e-17 2WXZ-C nrPDB 86 3e-17 1MTP-A nrPDB 79 3e-15 5M3Y-A nrPDB 77 1e-14 5C98-A nrPDB 43 2e-04 4N9N-A nrPDB 30 2.5 2YCH-A nrPDB 29 4.5 3G2F-A nrPDB 28 6.4 6D4C-A nrPDB 28 6.8 4N5A-A nrPDB 28 10.0 >4AJU-A nrPDB Length = 387 Score = 798 bits (2062), Expect = 0.0, Method: Compositional matrix adjust. Identities = 385/385 (100%), Positives = 385/385 (100%) Query: 23 APSPQSPETPAPQNQTSRVVQAPKEEEEDEQEASEEKASEEEKAWLMASRQQLAKETSNF 82 APSPQSPETPAPQNQTSRVVQAPKEEEEDEQEASEEKASEEEKAWLMASRQQLAKETSNF Sbjct: 2 APSPQSPETPAPQNQTSRVVQAPKEEEEDEQEASEEKASEEEKAWLMASRQQLAKETSNF 61 Query: 83 GFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLP 142 GFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLP Sbjct: 62 GFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLP 121 Query: 143 SLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAK 202 SLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAK Sbjct: 122 SLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAK 181 Query: 203 RLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYK 262 RLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYK Sbjct: 182 RLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYK 241 Query: 263 TIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLTTDLVE 322 TIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLTTDLVE Sbjct: 242 TIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLTTDLVE 301 Query: 323 TWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSRV 382 TWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSRV Sbjct: 302 TWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSRV 361 Query: 383 LQRTVIEVDERGTEAVAGILSEITA 407 LQRTVIEVDERGTEAVAGILSEITA Sbjct: 362 LQRTVIEVDERGTEAVAGILSEITA 386 >4AJT-A nrPDB Length = 427 Score = 618 bits (1593), Expect = e-177, Method: Compositional matrix adjust. Identities = 292/378 (77%), Positives = 332/378 (87%), Gaps = 1/378 (0%) Query: 67 WLMASRQQLAKETSNFGFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKR 126 WL AS QQL+ ETS+FGF+LLRKISMRHDGN++FSPFG+S+AM LMLG G T+ QI+ Sbjct: 51 WLRAS-QQLSNETSSFGFNLLRKISMRHDGNVIFSPFGLSVAMVNLMLGTKGETKVQIEN 109 Query: 127 GLHLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYF 186 GL+LQAL P +LP+LFK ++ET S N +LGL+QGSFAFIHKDFD+KET+FNLSK+YF Sbjct: 110 GLNLQALSQAGPLILPALFKKVKETFSSNRDLGLSQGSFAFIHKDFDIKETYFNLSKKYF 169 Query: 187 DTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPF 246 D E V +NF+N+SQA+ L+NH I KET GKIPKLFDEINPETKLILVDY+LFKGKWLTPF Sbjct: 170 DIEYVSINFQNSSQARGLINHCIVKETEGKIPKLFDEINPETKLILVDYVLFKGKWLTPF 229 Query: 247 DPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKM 306 DP FTE DTFHLDKY+ IKVPMMY G F STFDK FRCH+LKLPYQGNATMLVVLMEK Sbjct: 230 DPSFTEADTFHLDKYRAIKVPMMYREGNFTSTFDKKFRCHILKLPYQGNATMLVVLMEKT 289 Query: 307 GDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFAD 366 GD+LALEDYLT DLVETWL+NMKTR MEVFFPKFKL+Q+YEMHELL+QMGIRR+FS AD Sbjct: 290 GDYLALEDYLTVDLVETWLQNMKTRKMEVFFPKFKLNQRYEMHELLKQMGIRRLFSTSAD 349 Query: 367 LSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYE 426 LSELSA RNLQVSRVLQ++V+EVDERGTEAV+G LSEI AYSMPP IKV+RPFHF+IYE Sbjct: 350 LSELSAMARNLQVSRVLQQSVLEVDERGTEAVSGTLSEIIAYSMPPAIKVNRPFHFIIYE 409 Query: 427 ETSGMLLFLGRVVNPTLL 444 E S MLLFLGRVVNPT+L Sbjct: 410 EMSRMLLFLGRVVNPTVL 427 >6EE5-A nrPDB Length = 379 Score = 275 bits (704), Expect = 2e-74, Method: Compositional matrix adjust. Identities = 150/374 (40%), Positives = 226/374 (60%), Gaps = 12/374 (3%) Query: 70 ASRQQLAKETSNFGFSLLRKISMRH-DGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGL 128 AS +LA+ ++F FSL R+++ D N+ FSP +S A+ L LGA G T TQI GL Sbjct: 16 ASSHKLAEANTDFAFSLYRELAKSSPDKNIFFSPVSISSALAMLSLGAKGDTHTQILEGL 75 Query: 129 HLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDT 188 + G F+ L +TL+R L L + F+ K + ++F SK+ + Sbjct: 76 GFNSEADIHQG-----FQHLLQTLNRPKGLQLKTANGLFVDKSLKLLDSFLEDSKKLYQA 130 Query: 189 ECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDP 248 E ++F + +AK+ +N ++ K+T GKI L +++ +T L+LV+ I FKGKW PFDP Sbjct: 131 EAFSVDF-DPEEAKKQINDWVEKQTNGKIKDLLKDLDSDTVLVLVNAIYFKGKWKKPFDP 189 Query: 249 VFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMG- 307 T+ + FH+D+ T+KVPMM GKF D C VL+LPY+GNA+ML++L ++ G Sbjct: 190 ENTKEEDFHVDEKTTVKVPMMSQKGKFYYYHDDELSCKVLELPYKGNASMLIILPDEGGL 249 Query: 308 DHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADL 367 H LE LT + + WL+++ R++E++ PKFK++ Y++ E+L +GI +FSP ADL Sbjct: 250 QH--LEQSLTPETLSKWLKSLTRRSVELYLPKFKIEGTYDLKEVLSNLGITDLFSPGADL 307 Query: 368 SELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYEE 427 S + T L VS+ + + V+EV+E GTEA A E S+PP K DRPF F+I E Sbjct: 308 SGI--TEEKLYVSKAVHKAVLEVNEEGTEAAAATFLEAIPMSIPPEFKADRPFLFLIREN 365 Query: 428 TSGMLLFLGRVVNP 441 +G +LF+G+VVNP Sbjct: 366 KTGSILFMGKVVNP 379 >3NE4-A nrPDB Length = 424 Score = 214 bits (544), Expect = 8e-56, Method: Compositional matrix adjust. Identities = 129/395 (32%), Positives = 213/395 (53%), Gaps = 5/395 (1%) Query: 50 EDEQEASEEKASEEEKAWLMASRQQLAKETSNFGFSLLRKISMRHDG-NMVFSPFGMSLA 108 ED Q + +K + ++ + F FSL R+++ + + N+ FSP ++ A Sbjct: 31 EDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIATA 90 Query: 109 MTGLMLGATGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSR-NLELGLTQGSFAF 167 L LG T +I GL+ L + F+ L TL++ + +L LT G+ F Sbjct: 91 FAMLSLGTKADTHDEILEGLNFN-LTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLF 149 Query: 168 IHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPE 227 + + + + F K+ + +E +NF + +AK+ +N Y+ K T+GKI L E++ + Sbjct: 150 LSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRD 209 Query: 228 TKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHV 287 T LV+YI FKGKW PF+ TE + FH+D+ T+KVPMM G F K V Sbjct: 210 TVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWV 269 Query: 288 LKLPYQGNATMLVVLMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYE 347 L + Y GNAT + L ++ G LE+ LT D++ +L N R+ + PK + Y+ Sbjct: 270 LLMKYLGNATAIFFLPDE-GKLQHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYD 328 Query: 348 MHELLRQMGIRRIFSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITA 407 + +L Q+GI ++FS ADLS ++ L++S+ + + V+ +DE+GTEA + E Sbjct: 329 LKSVLGQLGITKVFSNGADLSGVTEEAP-LKLSKAVHKAVLTIDEKGTEAAGAMFLEAIP 387 Query: 408 YSMPPVIKVDRPFHFMIYEETSGMLLFLGRVVNPT 442 S+PP +K ++PF F++ E+ + LF+G+VVNPT Sbjct: 388 MSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNPT 422 >4Y40-A nrPDB Length = 414 Score = 213 bits (542), Expect = 1e-55, Method: Compositional matrix adjust. Identities = 121/386 (31%), Positives = 213/386 (55%), Gaps = 8/386 (2%) Query: 59 KASEEEKAW--LMASRQQLAKETSNFGFSLLRKISMRHDG-NMVFSPFGMSLAMTGLMLG 115 KA E + W MA+++ LA++ + GF LL+K++ + G N+ SP +S A + L LG Sbjct: 31 KALSEVQGWKQRMAAKE-LARQNMDLGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLG 89 Query: 116 ATGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVK 175 A T +IK+G + + + P K L + E + +L L+ G+ FI + + Sbjct: 90 AQDSTLDEIKQGFNFRKM-PEK-DLHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQPQ 147 Query: 176 ETFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDY 235 F +K ++ E + NF+N A++ +N +I+++T GKI L + I+P T ++L +Y Sbjct: 148 RKFLEDAKNFYSAETILTNFQNLEMAQKQINDFISQKTHGKINNLIENIDPGTVMLLANY 207 Query: 236 ILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGN 295 I F+ +W FDP T+ + F L+K ++KVPMM+ +G + +D C +L++PYQ N Sbjct: 208 IFFRARWKHEFDPNVTKEEDFFLEKNSSVKVPMMFRSGIYQVGYDDKLSCTILEIPYQKN 267 Query: 296 ATMLVVLMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQM 355 T + +L ++ G LE L D W + R + V P+ + +++ + L + Sbjct: 268 ITAIFILPDE-GKLKHLEKGLQVDTFSRWKTLLSRRVVCVSVPRLHMTGTFDLKKTLSYI 326 Query: 356 GIRRIFSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIK 415 G+ +IF DL+++ A R+L+V + + +++DERGTE AG ++ P +K Sbjct: 327 GVSKIFEEHGDLTKI-APHRSLKVGEAVHKAELKMDERGTEGAAGTGAQTLPMETPLCVK 385 Query: 416 VDRPFHFMIYEETSGMLLFLGRVVNP 441 +D+P+ +IY E +LFLG++VNP Sbjct: 386 IDKPYLLLIYSEKIPSVLFLGKIVNP 411 >5HGC-A nrPDB Length = 380 Score = 211 bits (538), Expect = 4e-55, Method: Compositional matrix adjust. Identities = 122/374 (32%), Positives = 202/374 (54%), Gaps = 9/374 (2%) Query: 74 QLAKETSNFGFSLLRKISMRH-DGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQA 132 +L ++F F R+++ + N+ +SP +S A L LGA T++QI GL Sbjct: 10 KLVPNNADFAFQFFREVTQEAPNKNIFYSPVSISTAFAMLALGARSATQSQILEGLAFN- 68 Query: 133 LKPTKPGLLPSLFKGLRETLSR---NLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTE 189 L + + F L L+ ++L + F+ + F + +K + E Sbjct: 69 LTEIQEKEIHEGFHNLIHMLNHPEGGVQLNMMNA--IFVTAALALLRKFLDDAKALYQLE 126 Query: 190 CVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPV 249 +F ++A++ +N YI ++T GKI L +++P+T ++L ++ FKG W PF+ Sbjct: 127 AFTTDFNKPTEAEKQINDYIERKTHGKITNLVKDMDPQTVMLLASFVYFKGSWEKPFEAE 186 Query: 250 FTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDH 309 TE F +D T+KVPMMY G+F FD+ C V++L Y G+AT +VL K G Sbjct: 187 HTEEREFFVDAETTVKVPMMYQMGRFDFYFDEELSCTVVRLHYNGSATAFLVLPAK-GKM 245 Query: 310 LALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSE 369 LE L + ++ W ++ R M ++FPKF + YE+ LR+MGI +F+ ADLS Sbjct: 246 KQLEQTLDKETIQKWSDHLFQRFMNLYFPKFSISGSYEISNTLRKMGIVDVFTNQADLSG 305 Query: 370 LSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYEETS 429 ++ + +L+VS+V+ + ++VDE+GTEA A EI S PP I+ PF +I++ + Sbjct: 306 ITGSP-DLKVSKVVHKASLDVDEKGTEAAAATAVEIMPISFPPTIEFSHPFLMLIFDRDT 364 Query: 430 GMLLFLGRVVNPTL 443 LF+G++VNPT+ Sbjct: 365 NSTLFIGKIVNPTI 378 >6HGE-B nrPDB Length = 409 Score = 209 bits (532), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 130/395 (32%), Positives = 220/395 (55%), Gaps = 15/395 (3%) Query: 57 EEKASEEEKAWLMASRQQLAKETSNFGFSLLRKISMRH-DGNMVFSPFGMSLAMTGLMLG 115 EE ++E + + LA +F FSL +++ ++ D N++FSP +S A+ L LG Sbjct: 17 EENLTQENQDRGTHVDRGLASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLG 76 Query: 116 ATGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSRNL-ELGLTQGSFAFIHKDFDV 174 A T T+I +GL L T + F+ L TL+++ EL L+ G+ F+ + + Sbjct: 77 AHNTTLTEILKGLKFN-LTETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSL 135 Query: 175 KETFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVD 234 + F +KR + +E +F++++ AK+L+N Y+ TRGKI L +++ +T ++LV+ Sbjct: 136 LDRFTEDAKRLYGSEAFATDFQDSAAAKKLINDYVKNGTRGKITDLIKDLDSQTMMVLVN 195 Query: 235 YILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTF-DKNFRCHVLKLPYQ 293 YI FK KW PFDP T F+L K K + VPMM F D+ C V++L Y Sbjct: 196 YIFFKAKWEMPFDPQDTHQSRFYLSKKKWVMVPMMSLHHLTIPYFRDEELSCTVVQLNYT 255 Query: 294 GNATMLVVL--MEKMGDHLALEDYLTTDLVETWLRNMKTRNM-EVFFPKFKLDQKYEMHE 350 GNA+ L +L +KM + +E L+ + + W +++ R + E++ PKF + + Y +++ Sbjct: 256 GNASALFILPDQDKMEE---VEAMLSRETLNRWGDSLEFREIGELYLPKFSISRDYNLND 312 Query: 351 LLRQMGIRRIFSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYS- 409 +L Q+GI F+ ADLS ++ RNL VS+V+ + V++V E GTEA A +IT S Sbjct: 313 ILLQLGIEEAFTSKADLSGITG-ARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLLSA 371 Query: 410 ---MPPVIKVDRPFHFMIYEETSGMLLFLGRVVNP 441 +++ +RPF +I + + + F+ +V NP Sbjct: 372 LVETRTIVRFNRPFLMIIVDHFTWSIFFMSKVTNP 406 >2VDY-A nrPDB Length = 373 Score = 199 bits (506), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 108/369 (29%), Positives = 202/369 (54%), Gaps = 5/369 (1%) Query: 75 LAKETSNFGFSLLRK-ISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQAL 133 LA +F FSL + +++ N+ SP +S+A+ L LG G T Q+ +GL Sbjct: 7 LASANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLT 66 Query: 134 KPTKPGLLPSLFKGLRETLSR-NLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVP 192 + ++ + F+ L + ++ + L +T G+ F+ ++ E+F K Y+++E + Sbjct: 67 ERSETEIHQG-FQHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLA 125 Query: 193 MNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTE 252 MNF++ + A R +N Y+ +T+GKI LF ++ L+LV+YI FKG W PFD T Sbjct: 126 MNFQDWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTR 185 Query: 253 VDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLAL 312 + F++D+ +KVPMM + + D C ++++ Y GN T+ +L +K G + Sbjct: 186 EENFYVDETTVVKVPMMLQSSTISYLHDSELPCQLVQMNYVGNGTVFFILPDK-GKMNTV 244 Query: 313 EDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSA 372 L+ D + W + + ++++ PK + Y++ ++L +MGI +F+ A+ S ++ Sbjct: 245 IAALSRDTINRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTTQANFSRITQ 304 Query: 373 TGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYEETSGML 432 + L+ S+V+ + V++++E GTEA + E S P +++ ++PF MI++ + Sbjct: 305 DAQ-LKSSKVVHKAVLQLNEEGTEAAGAMFLEAIPRSKPIILRFNQPFIIMIFDHFTWSS 363 Query: 433 LFLGRVVNP 441 LFL RV+NP Sbjct: 364 LFLARVMNP 372 >2OL2-A nrPDB Length = 395 Score = 197 bits (500), Expect = 9e-51, Method: Compositional matrix adjust. Identities = 119/365 (32%), Positives = 195/365 (53%), Gaps = 9/365 (2%) Query: 81 NFGFSLLRKI-SMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPG 139 +F F L R + S N+ FSP +S+++ L LGA T+ QI GL L K ++ Sbjct: 36 DFTFDLYRALASAAPSQNIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKE 95 Query: 140 LLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNAS 199 L + L+E L+ G+ F D+++TF + K + + P NFR+++ Sbjct: 96 LHRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSA 155 Query: 200 QAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLD 259 A + +N Y+ K+T+GKI L ++ +I+V+YI FK KW T F+ T+ F++ Sbjct: 156 GAMKQINDYVAKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVT 215 Query: 260 KYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLTTD 319 ++VPMM ++ D+N C V+ +PYQGNAT L +L + G +E+ L+ Sbjct: 216 SETVVRVPMMSREDQYHYLLDRNLSCRVVGVPYQGNATALFILPSE-GKMQQVENGLSEK 274 Query: 320 LVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQV 379 + WL+ K R +E++ PKF ++ Y++ ++L +GI +F+ ADLS +S N+QV Sbjct: 275 TLRKWLKMFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGIS-NHSNIQV 333 Query: 380 SRVLQRTVIEVDERGTEAVAG---ILSEITAYSMPPVIKVDRPFHFMIYEETSGMLLFLG 436 S ++ + V+EVDE GT A A I + +A + +RPF I + +LFLG Sbjct: 334 SEMVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVDNN---ILFLG 390 Query: 437 RVVNP 441 +V P Sbjct: 391 KVNRP 395 >3DY0-A nrPDB Length = 336 Score = 190 bits (482), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 107/321 (33%), Positives = 176/321 (54%), Gaps = 3/321 (0%) Query: 81 NFGFSLLRKI-SMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPG 139 +F F L R + S N+ FSP +S+++ L LGA T+ QI GL L K ++ Sbjct: 11 DFTFDLYRALASAAPSQNIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKE 70 Query: 140 LLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNAS 199 L + L+E L+ G+ F D+++TF + K + + P NFR+++ Sbjct: 71 LHRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSA 130 Query: 200 QAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLD 259 A + +N Y+ K+T+GKI L ++ +I+V+YI FK KW T F+ T+ F++ Sbjct: 131 GAMKQINDYVAKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVT 190 Query: 260 KYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLTTD 319 ++VPMM ++ D+N C V+ +PYQGNAT L +L + G +E+ L+ Sbjct: 191 SETVVRVPMMSREDQYHYLLDRNLSCRVVGVPYQGNATALFILPSE-GKMQQVENGLSEK 249 Query: 320 LVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQV 379 + WL+ K R +E++ PKF ++ Y++ ++L +GI +F+ ADLS +S N+QV Sbjct: 250 TLRKWLKMFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGIS-NHSNIQV 308 Query: 380 SRVLQRTVIEVDERGTEAVAG 400 S ++ + V+EVDE GT A A Sbjct: 309 SEMVHKAVVEVDESGTRAAAA 329 >1JMJ-A nrPDB Length = 480 Score = 182 bits (461), Expect = 3e-46, Method: Compositional matrix adjust. Identities = 120/377 (31%), Positives = 186/377 (49%), Gaps = 10/377 (2%) Query: 73 QQLAKETSNFGFSLLR--KISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHL 130 Q+L + F F+L R K + N+ +P G+S AM + LG G T Q+ LH Sbjct: 105 QRLNILNAKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILHF 164 Query: 131 Q----ALKPTKPGLLPSLFKGLRETL-SRNLELGLTQGSFAFIHKDFDVKETFFNLSKRY 185 + A + + +LF+ L L RN L + +I K F + F + Y Sbjct: 165 KDFVNASSKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKTKVREY 224 Query: 186 FDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTP 245 + E +F + + + NH I K T+G I + I+P T++++++ I FKG W+ Sbjct: 225 YFAEAQIADFSDPAFISKTNNH-IMKLTKGLIKDALENIDPATQMMILNCIYFKGSWVNK 283 Query: 246 FDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEK 305 F T F L++ + +KV MM G F + D+ C +L+L Y G +ML+V+ K Sbjct: 284 FPVEMTHNHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVGGISMLIVVPHK 343 Query: 306 MGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFA 365 M LE LT +VE W ++M R EV PKFKL++ Y + E L+ MGIR +F Sbjct: 344 MSGMKTLEAQLTPRVVERWQKSMTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDKNG 403 Query: 366 DLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIY 425 +++ +S + + + + I V+E GT+A S VDRPF F+IY Sbjct: 404 NMAGIS--DQRIAIDLFKHQGTITVNEEGTQATTVTTVGFMPLSTQVRFTVDRPFLFLIY 461 Query: 426 EETSGMLLFLGRVVNPT 442 E + LLF+GRV NP+ Sbjct: 462 EHRTSCLLFMGRVANPS 478 >1YXA-A nrPDB Length = 398 Score = 181 bits (459), Expect = 5e-46, Method: Compositional matrix adjust. Identities = 122/374 (32%), Positives = 207/374 (55%), Gaps = 10/374 (2%) Query: 75 LAKETSNFGFSLLRKISMRH-DGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQAL 133 LA ++F FSL +++ +++ D N+VFSP +S A+ + LGA G T +I GL L Sbjct: 27 LASINTDFAFSLYKELVLKNPDTNIVFSPLSISAALALVSLGAKGNTLEEILEGLKFN-L 85 Query: 134 KPTKPGLLPSLFKGLRETLSR-NLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVP 192 T + F L + L++ ++ ++ GS FI K + F +K + E Sbjct: 86 TETSEADIHQGFGHLLQRLNQPKDQVQISTGSALFIEKRQQILTEFQEKAKTLYQAEAFT 145 Query: 193 MNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTE 252 +F+ QAK+L+N Y+ K+T+G I +L +++ T ++LV+YI FK KW PFDP+ T Sbjct: 146 ADFQQPRQAKKLINDYVRKQTQGMIKELVSDLDKRTLMVLVNYIYFKAKWKVPFDPLDTF 205 Query: 253 VDTFHLDKYKTIKVPMMYGAGKFASTF-DKNFRCHVLKLPYQGNATMLVVLMEKMGDHLA 311 F+ K + + VPMM F D+ C V++L Y GNA+ L +L ++ G Sbjct: 206 KSEFYCGKRRPVIVPMMSMEDLTTPYFRDEELSCTVVELKYTGNASALFILPDQ-GRMQQ 264 Query: 312 LEDYLTTDLVETWLRNMKTRNM-EVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSEL 370 +E L + + W ++K R + E+ PKF + Y + ++L ++GIR +FS ADLS + Sbjct: 265 VEASLQPETLRKWKNSLKPRMIDELHLPKFSISTDYSLEDVLSKLGIREVFSTQADLSAI 324 Query: 371 SATGRNLQVSRVLQRTVIEVDERGTEAVAGILSE---ITAYSMPPVIKVDRPFHFMIYEE 427 + T ++L+VS+V+ + V++V E GTEA A + ++A P + +RPF MI++ Sbjct: 325 TGT-KDLRVSQVVHKAVLDVAETGTEAAAATGVKFVPMSAKLYPLTVYFNRPFLIMIFDT 383 Query: 428 TSGMLLFLGRVVNP 441 + + F+ ++ NP Sbjct: 384 ETEIAPFIAKIANP 397 >1QMB-A nrPDB Length = 326 Score = 177 bits (448), Expect = 1e-44, Method: Compositional matrix adjust. Identities = 108/324 (33%), Positives = 177/324 (54%), Gaps = 5/324 (1%) Query: 80 SNFGFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPG 139 + F FSL R+++ + N+ FSP ++ A L LG T +I GL+ L Sbjct: 7 AEFAFSLYRQLAHQSSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFN-LTEIPEA 65 Query: 140 LLPSLFKGLRETLSR-NLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNA 198 + F+ L TL++ + +L LT G+ F+ + + + F K+ + +E +NF + Sbjct: 66 AIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDT 125 Query: 199 SQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHL 258 +AK+ +N Y+ K T+GKI L E++ +T LV+YI FKGKW PF+ TE + FH+ Sbjct: 126 EEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHV 185 Query: 259 DKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLTT 318 D+ T+KVPMM G F K VL + Y GNAT + L ++ G LE+ LT Sbjct: 186 DQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDE-GKLQHLENELTH 244 Query: 319 DLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQ 378 D++ +L N + R+ + PK + Y++ +L Q+GI ++FS ADLS ++ L+ Sbjct: 245 DIITKFLENDR-RSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAP-LK 302 Query: 379 VSRVLQRTVIEVDERGTEAVAGIL 402 +S+ + + V+ +DE+GTEA + Sbjct: 303 LSKAVHKAVLTIDEKGTEAAGAMF 326 >2XN5-A nrPDB Length = 350 Score = 170 bits (430), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 109/345 (31%), Positives = 181/345 (52%), Gaps = 6/345 (1%) Query: 70 ASRQQLAKETSNFGFSLLRKISMRH-DGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGL 128 A+ +++ ++F F+L R+ ++ D N+ FSP +S A+ L GA T+T+I L Sbjct: 6 ATLYKMSSINADFAFNLYRRFTVETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETL 65 Query: 129 HLQALKPTKPGLLPSLFKGLRETLS-RNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFD 187 L T + F+ L +L+ EL L G+ FI K F N K ++ Sbjct: 66 GFN-LTDTPMVEIQHGFQHLICSLNFPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYE 124 Query: 188 TECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFD 247 TE +F N S AK+ +N ++ +T+GK+ L ++ P T ++LV+YI FK +W PFD Sbjct: 125 TEVFSTDFSNISAAKQEINSHVEMQTKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFD 184 Query: 248 PVFTE-VDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKM 306 P TE +F +DK T++VPMM+ ++ D C VL++ Y NA L VL K Sbjct: 185 PSKTEDSSSFLIDKTTTVQVPMMHQMEQYYHLVDMELNCTVLQMDYSKNALALFVL-PKE 243 Query: 307 GDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFAD 366 G ++E +++ ++ W R ++ +++F PKF + Y++ L +MGI+ +S AD Sbjct: 244 GQMESVEAAMSSKTLKKWNRLLQKGWVDLFVPKFSISATYDLGATLLKMGIQHAYSENAD 303 Query: 367 LSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMP 411 S L+ L++S + V+ + E+GTEA + E S+P Sbjct: 304 FSGLTE-DNGLKLSNAAHKAVLHIGEKGTEAAGAMFLEAIPRSIP 347 >3NDA-A nrPDB Length = 377 Score = 167 bits (424), Expect = 7e-42, Method: Compositional matrix adjust. Identities = 115/376 (30%), Positives = 191/376 (50%), Gaps = 8/376 (2%) Query: 69 MASRQQLAKETSNFGFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGL 128 M +L K + FG LLR + + N+ FSP+ +S AM GA G T+ ++ +GL Sbjct: 1 MQEEAKLTKANNRFGLRLLRALPSGPEKNVFFSPYSVSTAMGMAFAGARGQTQQELSQGL 60 Query: 129 HLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDT 188 + T G+L + S L + A I + + ++ + + F Sbjct: 61 GFSDVDLTDAGVLDAYTHHTERLKSTPSNSTLDVANAAAIQRTLALLNSYESALQSSFGA 120 Query: 189 ECVPMNFRNASQAK-RLMNHYINKETRGKIPKLFDE-INPETKLILVDYILFKGKWLTPF 246 E ++F QA +N+++ ++T KI KLF+E ++P+T L+L++ I FKG+W T F Sbjct: 121 ELHKVDFAGEPQAAVDFVNNWVKRKTHDKIEKLFNEPLDPDTLLVLLNAIYFKGEWNTAF 180 Query: 247 DPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQG-NATMLVVLMEK 305 TE F ++V M + F + + V++LPY+G + TM ++L ++ Sbjct: 181 VKEHTEKRQFFNGGVTPVEVDTMRLEARIKYRFFDDLQVEVVELPYRGLDYTMAILLPKE 240 Query: 306 MGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFA 365 L+ LT D + +L +++ R + V PKFKL+ KY + L+ +GI++IF A Sbjct: 241 NTGVEGLKQNLTIDRFQNYLSDLRERKITVLLPKFKLETKYSLKAPLQSLGIKQIFESGA 300 Query: 366 DLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPP---VIKVDRPFHF 422 DLS ++ +L+VS V + V+EV+E GT A A I YS+ P V +VD PF F Sbjct: 301 DLSGINDG--SLRVSAVEHKAVVEVNEEGTVAAATTGVVIVPYSLGPEPVVFRVDHPFLF 358 Query: 423 MIYEETSGMLLFLGRV 438 I + + F+G+V Sbjct: 359 FIRNTRTDDIFFVGQV 374 >1BY7-A nrPDB Length = 382 Score = 163 bits (412), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 102/362 (28%), Positives = 191/362 (52%), Gaps = 23/362 (6%) Query: 97 NMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSRNL 156 N+ SP+ +S M + +G+ G TE Q+ + L + + S F+ L ++ + Sbjct: 27 NLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGAAADKIHSS-FRSLSSAINAST 85 Query: 157 ELGLTQG-SFAFIHKDFDVKETFFNLSKRYFDTECVPMNF-RNASQAKRLMNHYINKETR 214 L + + F K +E + L ++Y+ +E ++F A +A++ +N ++ +T+ Sbjct: 86 GNYLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTK 145 Query: 215 GKIPKLFDE--INPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGA 272 GKIP L E ++ +T+++LV+ + FKGKW TPF+ + F ++ + V MMY Sbjct: 146 GKIPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLR 205 Query: 273 GKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLA----LEDYLTTDLVETWLR-- 326 K + ++ + +L+LPY G+ +M ++L +++ D LE +T D + W Sbjct: 206 EKLNIGYIEDLKAQILELPYAGDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKD 265 Query: 327 NMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSP----FADLSELSATGRNLQVSRV 382 M +EV+ P+FKL++ YE+ +LR MG+ F+ F+ +SE + +L +S V Sbjct: 266 KMAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERN----DLFLSEV 321 Query: 383 LQRTVIEVDERGTEAVA---GILSEITAYSMPPVIKVDRPFHFMIYEETSGMLLFLGRVV 439 + +++V+E GTEA A G+++ T + P + D PF F+I + + +LF GR Sbjct: 322 FHQAMVDVNEEGTEAAAGTGGVMTGRTGHGGPQFV-ADHPFLFLIMHKITNCILFFGRFS 380 Query: 440 NP 441 +P Sbjct: 381 SP 382 >1ATT-A nrPDB Length = 429 Score = 158 bits (400), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 118/411 (28%), Positives = 202/411 (49%), Gaps = 25/411 (6%) Query: 52 EQEASEEKASEEEKAWLMASR-QQLAKETSNFGFSLLRKI--SMRHDGNMVFSPFGMSLA 108 E++A+E + SE++ R +L+K S+F + + + S ++ N+ SP +S A Sbjct: 24 EKKATEGQGSEQKIPGATNRRVWELSKANSHFATAFYQHLADSKNNNDNIFLSPLSISTA 83 Query: 109 MTGLMLGATGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSR--NLELGLTQGSFA 166 LGA T TQ+ + + F L L R N L + Sbjct: 84 FAMTKLGACNNTLTQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKSSELVSANRL 143 Query: 167 FIHKDFDVKETFFNLSKRYFDTECVPMNFR-NASQAKRLMNHYINKETRGKIPKLF--DE 223 F K ET+ ++S+ + + P++F+ NA Q++ +N +I+ +T G+I + Sbjct: 144 FGDKSITFNETYQDISEVVYGAKLQPLDFKGNAEQSRLTINQWISNKTEGRITDVIPPQA 203 Query: 224 INPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNF 283 IN T L+LV+ I FKG W + F P T + F+ ++ V MMY KF + Sbjct: 204 INEFTVLVLVNTIYFKGLWKSKFSPENTRKELFYKADGESCSVLMMYQESKF------RY 257 Query: 284 R-----CHVLKLPYQGNATMLVVLMEKMGDHLA-LEDYLTTDLVETWLRNMKTRNMEVFF 337 R VL+LP++G+ +V+++ K+ LA +E LT D+++ WL + + V Sbjct: 258 RRVAESTQVLELPFKGDDITMVLILPKLEKTLAKVEQELTPDMLQEWLDELTETLLVVHM 317 Query: 338 PKFKLDQKYEMHELLRQMGIRRIFSP-FADLSELSATGR-NLQVSRVLQRTVIEVDERGT 395 P+F+++ + + E L+ MG+ +FSP + L + A GR +L VS + +EV+E G+ Sbjct: 318 PRFRIEDSFSVKEQLQDMGLEDLFSPEKSRLPGIVAEGRSDLYVSDAFHKAFLEVNEEGS 377 Query: 396 EAVAGILSEITAYSMPP---VIKVDRPFHFMIYEETSGMLLFLGRVVNPTL 443 EA A + I S+ K +RPF +I E ++F+GRV NP + Sbjct: 378 EAAASTVISIAGRSLNSDRVTFKANRPFLVLIREVALNTIIFMGRVANPCV 428 >4DY0-A nrPDB Length = 379 Score = 154 bits (388), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 111/375 (29%), Positives = 192/375 (51%), Gaps = 21/375 (5%) Query: 80 SNFGFSLLRKI--SMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTK 137 SN G + +I S HD N+V SP G++ + L LGA G T+ Q+ ++ Sbjct: 13 SNTGIQVFNQIVKSRPHD-NIVISPHGIASVLGMLQLGADGRTKKQLA-----MVMRYGV 66 Query: 138 PGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRN 197 G+ L K + +S+ + +T + F+ +++ F +K F E +NF + Sbjct: 67 NGVGKILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFED 126 Query: 198 ASQAKRLMNHYINKETRGKI-----PKLFDEINPETKLILVDYILFKGKWLTPFDPVFTE 252 + A +N ++ ETR I P L D + T+L+LV+ + FKG W + F P T+ Sbjct: 127 PASACDSINAWVKNETRDMIDNLLSPDLIDGV--LTRLVLVNAVYFKGLWKSRFQPENTK 184 Query: 253 VDTFHLDKYKTIKVPMMYGAGKF---ASTFDKNFRCHVLKLPYQGNA-TMLVVLMEKMGD 308 TF K+ +VPM+ F +++ + + ++LPY G + +ML+ L + Sbjct: 185 KRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALPTESST 244 Query: 309 HL-ALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIF-SPFAD 366 L A+ +++T +++W+ M + ++V PKF + ++ E L+ +GI +F S A+ Sbjct: 245 PLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKAN 304 Query: 367 LSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYE 426 ++++ NL VS +LQ+ IEV E GT+A A + + A S PP VDRPF F I Sbjct: 305 FAKITTGSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSSPPWFIVDRPFLFFIRH 364 Query: 427 ETSGMLLFLGRVVNP 441 +G +LF+G++ P Sbjct: 365 NPTGAVLFMGQINKP 379 >5INW-A nrPDB Length = 421 Score = 153 bits (387), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 109/386 (28%), Positives = 187/386 (48%), Gaps = 8/386 (2%) Query: 29 PETPAP-QNQTSRVVQAPKEEEEDEQEASEEKASEEEKAWLMASRQQLAKETSNFGFSLL 87 PE AP Q+ + + EE+ DE+E ++ K + Q++A + GF L Sbjct: 34 PEPLAPGQSPAASSEEGSSEEKGDEREPHGDEGKRGRKDKKKSKTQRIASAVNGLGFRLY 93 Query: 88 RKI--SMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQA-LKPTKPGLLPSL 144 +++ N+ FSP ++ A+ + GA G T ++ L + L K Sbjct: 94 KQVLGGAGPADNIFFSPLSIASALGVVTAGANGSTRAELDTALGFKEFLHGKKKAKSMKY 153 Query: 145 FKGLRETL-SRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAKR 203 F L L R+ L + F K + F F + ++F ++ A Sbjct: 154 FARLNGALYKRSAGFELMGKNVVFSKKGLWLYRQFTRTVAHLFKSNVRSVDFGDSKNAVE 213 Query: 204 LMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKT 263 LMN YI K T K P + +++ +T L++V+ I FKG W F+P T+ F ++ + Sbjct: 214 LMNAYIEKVTSKKFPDVISDVDTDTSLVIVNVIYFKGSWGNKFEPDLTKNVRFWVNSSYS 273 Query: 264 IKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLTTDLVET 323 + VP M+ K + T D+ R V+KLPY+G A+MLV++ + D +E+ ++ + +E Sbjct: 274 MMVPTMHQRAKLSYTQDRKLRSTVVKLPYEGGASMLVIVPHRTEDLPKVEESVSQEQLEE 333 Query: 324 WLRNMKTRN--MEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSR 381 WL + N +++ PKFK+ Y++ L MG+ +FS ADLS ++ + L V + Sbjct: 334 WLSLLGPSNHYVQLSLPKFKISVSYDLKAYLSAMGMSSMFSYGADLSRITGM-QKLHVDK 392 Query: 382 VLQRTVIEVDERGTEAVAGILSEITA 407 + ++V+ V+E GTEA A + I A Sbjct: 393 ITHKSVLHVNEEGTEAKAETVVGIMA 418 >2V95-A nrPDB Length = 371 Score = 153 bits (386), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 92/374 (24%), Positives = 199/374 (53%), Gaps = 11/374 (2%) Query: 71 SRQQLAKETSNFGFSLLRK-ISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLH 129 S + LA +F F+L ++ +++ D N + SP +S+A+ + LG+ +TQ + L Sbjct: 5 SHRGLAPTNVDFAFNLYQRLVALNPDKNTLISPVSISMALAMVSLGSA---QTQSLQSLG 61 Query: 130 LQALKPTKPGLLPSLFKGLRETLSR-NLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDT 188 L T + F+ L L + + L + G+ F+ + +K++F K+Y+++ Sbjct: 62 FN-LTETSEAEIHQSFQYLNYLLKQSDTGLEMNMGNAMFLLQKLKLKDSFLADVKQYYES 120 Query: 189 ECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDP 248 E + ++F + ++A + +N ++ +T+GKI +F +++ ILV+YI +G W PF P Sbjct: 121 EALAIDFEDWTKASQQINQHVKDKTQGKIEHVFSDLDSPASFILVNYIFLRGIWELPFSP 180 Query: 249 VFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGD 308 T + F++++ T+KVPMM +G D F C ++++ Y GN T +L ++ G Sbjct: 181 ENTREEDFYVNETSTVKVPMMVQSGSIGYFRDSVFPCQLIQMDYVGNGTAFFILPDQ-GQ 239 Query: 309 HLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLS 368 + L+ D ++ W + M R + ++ PKF + Y++ ++L + I+ + + + S Sbjct: 240 MDTVIAALSRDTIDRWGKLMTPRQVNLYIPKFSMSDTYDLKDVLEDLNIKDLLT---NQS 296 Query: 369 ELSATGRNLQVS-RVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYEE 427 + S +++ ++ ++ + ++++DE + + + S P IK ++PF +++++ Sbjct: 297 DFSGNTKDVPLTLTMVHKAMLQLDEGNVLPNSTNGAPLHLRSEPLDIKFNKPFILLLFDK 356 Query: 428 TSGMLLFLGRVVNP 441 + L + +VVNP Sbjct: 357 FTWSSLMMSQVVNP 370 >1C5G-A nrPDB Length = 402 Score = 153 bits (386), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 107/377 (28%), Positives = 188/377 (49%), Gaps = 15/377 (3%) Query: 75 LAKETSNFGFSLLRKISM-RHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQAL 133 +A S+FG + ++++ D N+VFSP+G++ + L L G T+ QI+ + Sbjct: 31 VAHLASDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAM---GF 87 Query: 134 KPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPM 193 K G+ P+L +E + + ++ F+ +D + + F R F + + Sbjct: 88 KIDDKGMAPALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQV 147 Query: 194 NFRNASQAKRLMNHYINKETRGKIPKLFDE--INPETKLILVDYILFKGKWLTPFDPVFT 251 +F +A+ ++N ++ T+G I L + ++ T+L+LV+ + F G+W TPF T Sbjct: 148 DFSEVERARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSST 207 Query: 252 EVDTFHLDKYKTIKVPMMYGAGKFA----STFDKNFRCHVLKLPYQGNATMLVVLM--EK 305 FH T+ VPMM KF +T D ++ +L+LPY G+ + + EK Sbjct: 208 HRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPDGHY-YDILELPYHGDTLSMFIAAPYEK 266 Query: 306 MGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPF- 364 AL + L+ L+ W NM + PKF L+ + ++ + L +G+ +F F Sbjct: 267 EVPLSALTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQ 326 Query: 365 ADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMI 424 AD + LS L V++ LQ+ IEV+E GT A + ++A P I +DRPF F++ Sbjct: 327 ADFTSLSDQ-EPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPEEIIMDRPFLFVV 385 Query: 425 YEETSGMLLFLGRVVNP 441 +G +LF+G+V+ P Sbjct: 386 RHNPTGTVLFMGQVMEP 402 >4GA7-A nrPDB Length = 389 Score = 151 bits (382), Expect = 5e-37, Method: Compositional matrix adjust. Identities = 115/384 (29%), Positives = 199/384 (51%), Gaps = 21/384 (5%) Query: 73 QQLAKETSNFGFSLLRKISMRH-DGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQ 131 +QL+ + F L +S + GN+ SPF +S AM + LG G T Q+ + H Sbjct: 12 EQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHFN 71 Query: 132 ALKPTKPGLLPSLFKGLRETLS-RNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTEC 190 ++ + S F+ L ++ R L + + K ++ F +++ + + Sbjct: 72 TVEE-----VHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADL 126 Query: 191 VPMNFRNASQ-AKRLMNHYINKETRGKIPKLFDE--INPETKLILVDYILFKGKWLTPFD 247 ++F++AS+ A++ +N ++ +T GKIP+L ++ TKL+LV+ I FKG W F Sbjct: 127 ASVDFQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFM 186 Query: 248 PVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNA-TMLVVLMEKM 306 T F L+K V MMY KFA + ++ +C VL+LPYQG +M+++L + + Sbjct: 187 KEATTNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDI 246 Query: 307 GDHLA----LEDYLTTDLVETWLR--NMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRI 360 D +E+ LT + + W + N+ + V P+FKL++ Y ++ L ++G++ + Sbjct: 247 EDESTGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDL 306 Query: 361 F-SPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPP--VIKVD 417 F S ADLS +S R++ +S+++ ++ +EV+E GTEA A T P D Sbjct: 307 FNSSKADLSGMSG-ARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMDDPEENFTAD 365 Query: 418 RPFHFMIYEETSGMLLFLGRVVNP 441 PF F I +SG +LFLGR +P Sbjct: 366 HPFLFFIRHNSSGSILFLGRFSSP 389 >4KDS-A nrPDB Length = 386 Score = 150 bits (380), Expect = 8e-37, Method: Compositional matrix adjust. Identities = 107/387 (27%), Positives = 195/387 (50%), Gaps = 28/387 (7%) Query: 70 ASRQQLAKETSNFGFSLLRKISMRHDG-NMVFSPFGMSLAMTGLMLGATGPT--ETQIKR 126 A+ L ++ ++FG + +++ G N+ FSP+G++ + LGA G T K Sbjct: 10 AAISNLQEKQTDFGMRVFSQVAQNSKGSNLAFSPYGVATILAMAQLGAGGNTLKTLNAKL 69 Query: 127 GLHLQALKPTKPGLLPSLFKGLRETLSRNL--ELGLTQGSFAFIHKDFDVKETFFNLSKR 184 G LQ + L L R++ E G+ S + + +++ F + Sbjct: 70 GFSLQERGMARQQRL----------LQRDISSEEGVELASGVMVERKMALEKGFRRGLGK 119 Query: 185 YFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDE--INPETKLILVDYILFKGKW 242 F ++F QA ++N +++ T G IP + ET+++L++ + F+G W Sbjct: 120 AFQASPHQLDFSRPDQALDIINAWVSDHTAGTIPSFLSSGALTDETRMVLLNALHFQGLW 179 Query: 243 LTPFDPVFTEVDTFHLDKYKTIKVPMM-----YGAGKFASTFDKNFRCHVLKLPYQGNA- 296 PFDP TE FH ++ VPMM + G+F + ++ V+++PY+G + Sbjct: 180 KVPFDPKMTEERLFHCANGSSVPVPMMRLTHRFKYGEFVTPDGVDY--DVIEVPYEGESL 237 Query: 297 -TMLVVLMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQM 355 +LV E +L LTT ++ W + M++ ++ P+F LD + E+ +L QM Sbjct: 238 SMLLVSPFEPETPVSSLSSELTTQRLQQWRQEMRSVKRQLVLPRFTLDSEVELKSILIQM 297 Query: 356 GIRRIFS-PFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVI 414 G+ +F+ AD + ++ T + L VS+VLQ+ IEV+E GT+A A + + + I Sbjct: 298 GLGDMFNLAKADFTRIT-TEQPLCVSKVLQKVKIEVNEEGTKASAATAAILFSRMAVEEI 356 Query: 415 KVDRPFHFMIYEETSGMLLFLGRVVNP 441 ++RPF F+I+ +++G +LF+G+V P Sbjct: 357 TMNRPFLFLIHHKSTGAVLFMGQVNQP 383 >6F02-A nrPDB Length = 389 Score = 150 bits (379), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 113/381 (29%), Positives = 196/381 (51%), Gaps = 17/381 (4%) Query: 74 QLAKETSNFGFSLLRKISMRHDG-NMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQA 132 ++A ++F F I+ G N+ FSP +S A L LGA + +QI GL Sbjct: 6 KIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNL 65 Query: 133 LKPTKPGLLPSLFKGLRETLS---RNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTE 189 + ++ + F+ L TL+ LE + GS F+ + F N + ++ + Sbjct: 66 TELSESDVHRG-FQHLLHTLNLPGHGLETRV--GSALFLSHNLKFLAKFLNDTMAVYEAK 122 Query: 190 CVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPV 249 NF + +L+N ++ KETRGKI L E+ + ++LV+YI FK W PF Sbjct: 123 LFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISS 182 Query: 250 FTEVDTFHLDKYKTIKVPMMYGAGKFASTF-DKNFRCHVLKLPYQGNATMLVVLMEKMGD 308 T F++D+ T++VPMM + D+ C VL++ Y+G+AT+ +L + G Sbjct: 183 RTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQ-GK 241 Query: 309 HLALEDYLTTDLVETWLRNMKTRN----MEVFFPKFKLDQKYEMHELLRQMGIRRIFSPF 364 +E+ LT +++ W ++ RN +E+ PKF + Y + ++L ++G +FS + Sbjct: 242 MREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKW 301 Query: 365 ADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPP---VIKVDRPFH 421 ADLS ++ + L+ S+ + ++VDE GTEA A I +S +++ +RPF Sbjct: 302 ADLSGITKQQK-LEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFL 360 Query: 422 FMIYEETSGMLLFLGRVVNPT 442 +I+ ++ +LFLG+VV+PT Sbjct: 361 VVIFSTSTQSVLFLGKVVDPT 381 >3LW2-A nrPDB Length = 379 Score = 150 bits (378), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 105/375 (28%), Positives = 185/375 (49%), Gaps = 13/375 (3%) Query: 76 AKETSNFGFSLLRKI-SMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALK 134 A + ++FG + +++ D N+VFSP+G+S + L + G T QI+ + + + Sbjct: 9 AHQATDFGVKVFQQVVQASKDRNVVFSPYGVSSVLAMLQMTTAGKTRRQIQDAMGFKVNE 68 Query: 135 PTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMN 194 L L K L ++N ++ F+ +D ++ + F + F T ++ Sbjct: 69 KGTAHALRQLSKELMGPWNKN---EISTADAIFVQRDLELVQGFMPHFFKLFQTMVKQVD 125 Query: 195 FRNASQAKRLMNHYINKETRGKIPKLFDE--INPETKLILVDYILFKGKWLTPFDPVFTE 252 F +A+ ++N ++ + T+G I L + ++ T+L+LV+ + F G+W TPF T Sbjct: 126 FSEVERARFIINDWVERHTKGMINDLLAKGAVDELTRLVLVNALYFSGQWKTPFLEASTH 185 Query: 253 VDTFHLDKYKTIKVPMMYGAGKFAST---FDKNFRCHVLKLPYQGNA-TMLVVLMEKMGD 308 FH T+ VPMM + KF T V++LPYQG+ +M + + Sbjct: 186 QRLFHKSDGSTVSVPMMAQSNKFNYTEFTTPDGLEYDVVELPYQGDTLSMFIAAPFEKDV 245 Query: 309 HL-ALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSP-FAD 366 HL AL + L +L+ W NM + PKF L+ + ++ L ++G+ +FS AD Sbjct: 246 HLSALTNILDAELIRQWKGNMTRLPRLLILPKFSLETEVDLRGPLEKLGMPDMFSATLAD 305 Query: 367 LSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYE 426 + LS L V++ LQ+ IEV+E GT A + I+A P + +DR F F++ Sbjct: 306 FTSLS-DQEQLSVAQALQKVRIEVNESGTVASSSTAFVISARMAPTEMVIDRSFLFVVRH 364 Query: 427 ETSGMLLFLGRVVNP 441 + +LF+G+V+ P Sbjct: 365 NPTETILFMGQVMEP 379 >4EB1-I nrPDB Length = 440 Score = 149 bits (377), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 118/425 (27%), Positives = 199/425 (46%), Gaps = 40/425 (9%) Query: 47 EEEEDEQEASEEKASE--EEKAWLMASRQQLAKETSNFGFSLLRKI--SMRHDGNMVFSP 102 E++ E E SE+K E + W +L+K S F + + + S + N+ SP Sbjct: 27 EKKATEDEGSEQKIPEATNRRVW------ELSKANSRFATTFYQHLADSKNDNDNIFLSP 80 Query: 103 FGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSR--NLELGL 160 +S A LGA T Q+ + + F L L R N L Sbjct: 81 LSISTAFAMTKLGACNDTLQQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKASKL 140 Query: 161 TQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFR-NASQAKRLMNHYINKETRGKIPK 219 + F K ET+ ++S+ + + P++F+ NA Q++ +N +++ +T G+I Sbjct: 141 VSANRLFGDKSLTFNETYQDISELVYGAKLQPLDFKENAEQSRAAINKWVSNKTEGRITD 200 Query: 220 LF--DEIN--------PETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMM 269 + + IN T L+LV+ I FKG W + F P T + F+ ++ MM Sbjct: 201 VIPSEAINVLVLVNTRTSTVLVLVNTIYFKGLWKSKFSPENTRKELFYKADGESCSASMM 260 Query: 270 YGAGKFASTFDKNFR-----CHVLKLPYQGNATMLVVLMEKMGDHLA-LEDYLTTDLVET 323 Y GKF +R VL+LP++G+ +V+++ K LA +E LT ++++ Sbjct: 261 YQEGKF------RYRRVAEGTQVLELPFKGDDITMVLILPKPEKSLAKVEKELTPEVLQE 314 Query: 324 WLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSP-FADLSELSATGR-NLQVSR 381 WL ++ + V P+F+++ + + E L+ MG+ +FSP + L + A GR +L VS Sbjct: 315 WLDELEEMMLVVHMPRFRIEDGFSLKEQLQDMGLVDLFSPEKSKLPGIVAEGRDDLYVSD 374 Query: 382 VLQRTVIEVDERGTEAVAGILSEITAYSMPP---VIKVDRPFHFMIYEETSGMLLFLGRV 438 + +EV+E G+EA A I S+ P K +RPF I E ++F+GRV Sbjct: 375 AFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVTFKANRPFLVFIREVPLNTIIFMGRV 434 Query: 439 VNPTL 443 NP + Sbjct: 435 ANPCV 439 >3OZQ-A nrPDB Length = 376 Score = 146 bits (368), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 102/383 (26%), Positives = 192/383 (50%), Gaps = 30/383 (7%) Query: 70 ASRQQLAKETSNFGFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLH 129 A+ Q+ ++F S+ +++ N + SPF + + G G T +I++ LH Sbjct: 6 ATLQEFPNAVNSFTPSVYKEVLKTEKANFLVSPFSAATLLALAQSGCRGDTAEEIRQVLH 65 Query: 130 LQALKPTKPGLLPSLFKGLRETLSR--NLELGLTQGSFAFIHKDFDVKETFFNLSKRYFD 187 + G ++E LS+ N E L + ++ +F V+E F ++ + Sbjct: 66 FVGDREKAEG-------AVKEVLSKLTNEEYTLHTANKIYVKTNFSVREEFQKIAVEVYG 118 Query: 188 TECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDE--INPETKLILVDYILFKGKWLTP 245 + ++F + A +LMN ++ ++T+ KI L D +N T+++L++ + F KWL P Sbjct: 119 AQSENVDFSEKNDAAKLMNAWVEEQTQHKIQNLVDPEILNNLTRVVLINALYFNAKWLVP 178 Query: 246 FDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCH-----VLKLPYQGNATMLV 300 F P T FH + ++V MY ++ + ++ CH +L+LP++G A++ + Sbjct: 179 FPPFHTRKSDFHKSAKEVVQVDTMYLDEQYFNYYE----CHHLDAKLLELPFKGGASLTI 234 Query: 301 VLMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRI 360 VL ++ ++LE + + N+ + + V PKFK++ + ++L+++G+++ Sbjct: 235 VLSNQIEGLVSLESKIKRSFLP---HNLTKQLVNVALPKFKIESTVDFKKVLKKLGVKKA 291 Query: 361 FSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAG-----ILSEITAYSMPPVIK 415 F ADLS ++ +L +S ++Q++ I+V E G EA A IL E+ P Sbjct: 292 FGDEADLSGIAGEKGDLVISNIVQKSFIDVSEEGVEAAAATYIPVILPEMALPDSPKQFI 351 Query: 416 VDRPFHFMIYEETSGMLLFLGRV 438 VD PF F I + GM+LF GRV Sbjct: 352 VDHPFIFYI--KVKGMILFAGRV 372 >1UHG-A nrPDB Length = 385 Score = 145 bits (365), Expect = 4e-35, Method: Compositional matrix adjust. Identities = 98/377 (25%), Positives = 184/377 (48%), Gaps = 18/377 (4%) Query: 82 FGFSLLRKISMRH-DGNMVFSPFGMSLAMTGLMLGATGPTETQIKR----------GLHL 130 F F + +++ + H + N+ + P + A+ + LGA T TQI + G + Sbjct: 10 FCFDVFKELKVHHANENIFYCPIAIMSALAMVYLGAKDSTRTQINKVVRFDKLPGFGDSI 69 Query: 131 QALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTEC 190 +A T + SL L + N + S + + + + + K + Sbjct: 70 EAQCGTSVNVHSSLRDILNQITKPNDVYSFSLASRLYAEERYPILPEYLQCVKELYRGGL 129 Query: 191 VPMNFRNAS-QAKRLMNHYINKETRGKIPKLF--DEINPETKLILVDYILFKGKWLTPFD 247 P+NF+ A+ QA+ L+N ++ +T G I + ++ +T ++LV+ I+FKG W F Sbjct: 130 EPINFQTAADQARELINSWVESQTNGIIRNVLQPSSVDSQTAMVLVNAIVFKGLWEKAFK 189 Query: 248 PVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPY-QGNATMLVVLMEKM 306 T+ F + + ++ V MMY G F + + +L+LP+ G +MLV+L +++ Sbjct: 190 DEDTQAMPFRVTEQESKPVQMMYQIGLFRVASMASEKMKILELPFASGTMSMLVLLPDEV 249 Query: 307 GDHLALEDYLTTDLVETWLRN--MKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPF 364 LE + + + W + M+ R ++V+ P+ K+++KY + +L MGI +FS Sbjct: 250 SGLEQLESIINFEKLTEWTSSNVMEERKIKVYLPRMKMEEKYNLTSVLMAMGITDVFSSS 309 Query: 365 ADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMI 424 A+LS +S + +L++S+ + E++E G E V + + A S+ + D PF F I Sbjct: 310 ANLSGIS-SAESLKISQAVHAAHAEINEAGREVVGSAEAGVDAASVSEEFRADHPFLFCI 368 Query: 425 YEETSGMLLFLGRVVNP 441 + +LF GR V+P Sbjct: 369 KHIATNAVLFFGRCVSP 385 >1IMV-A nrPDB Length = 398 Score = 141 bits (356), Expect = 6e-34, Method: Compositional matrix adjust. Identities = 104/384 (27%), Positives = 197/384 (51%), Gaps = 13/384 (3%) Query: 62 EEEKAWLMASRQQLAKETSNFGFSLLR-KISMRHDGNMVFSPFGMSLAMTGLMLGATGPT 120 EEE + +LA SNFG+ L R + SM N++ SP ++ A++ L LGA T Sbjct: 21 EEEDPFFKVPVNKLAAAVSNFGYDLYRVRSSMSPTTNVLLSPLSVATALSALSLGADERT 80 Query: 121 ETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFN 180 E+ I R L+ + + P + +K L +T++ + L S K +K +F Sbjct: 81 ESIIHRALYYDLI--SSPDIH-GTYKELLDTVTAP-QKNLKSASRIVFEKKLRIKSSFVA 136 Query: 181 LSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKG 240 ++ + T + N + +N+++ + +GK+ + EI E ++L+ FKG Sbjct: 137 PLEKSYGTRPRVLT-GNPRLDLQEINNWVQAQMKGKLARSTKEIPDEISILLLGVAHFKG 195 Query: 241 KWLTPFDPVFTEVDTFHLDKYKTIKVPMMYG-AGKFASTFDKNFRCHVLKLPYQGNATML 299 +W+T FD T ++ F+LD+ +T++VPMM D + C + +LP G+ +++ Sbjct: 196 QWVTKFDSRKTSLEDFYLDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSII 255 Query: 300 VVLMEKMGDHLAL-EDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIR 358 L K+ +L L E+ LT++ + R +KT + PK KL + E+ + L++M ++ Sbjct: 256 FFLPLKVTQNLTLIEESLTSEFIHDIDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQ 315 Query: 359 RIF-SPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVD 417 +F SP D S++ TG+ +++++V R E +E G + + P ++ Sbjct: 316 SLFDSP--DFSKI--TGKPIKLTQVEHRAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLN 371 Query: 418 RPFHFMIYEETSGMLLFLGRVVNP 441 +PF F++ + +G LLF+G++++P Sbjct: 372 QPFIFVLRDTDTGALLFIGKILDP 395 >3F02-A nrPDB Length = 359 Score = 140 bits (353), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 83/315 (26%), Positives = 161/315 (51%), Gaps = 12/315 (3%) Query: 94 HDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRETLS 153 D N++FSP ++LAM + LGA G T+ +I+ + +LK + F + + Sbjct: 39 EDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKNGEEFSFLKEFSNM--VTA 96 Query: 154 RNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINKET 213 + + + + F+ F V E F + K+YF+ ++F +N ++ T Sbjct: 97 KESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFSQNVAVANYINKWVENNT 156 Query: 214 RGKIPKLFD--EINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYG 271 + L + + T L L++ + FKG W + F P T +F D +++PMMY Sbjct: 157 NNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQ 216 Query: 272 AGKF------ASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLA-LEDYLTTDLVETW 324 G+F + + VL++PY+G+ +++++ + LA LE + LVE W Sbjct: 217 QGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEVPLATLEPLVKAQLVEEW 276 Query: 325 LRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSRVLQ 384 ++K + +EV+ P+F ++Q+ ++ ++L+ +GI IF A+L+ LS + + +S+ + Sbjct: 277 ANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIKDANLTGLS-DNKEIFLSKAIH 335 Query: 385 RTVIEVDERGTEAVA 399 ++ +EV+E G+EA A Sbjct: 336 KSFLEVNEEGSEAAA 350 >4P0F-A nrPDB Length = 393 Score = 140 bits (353), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 106/380 (27%), Positives = 184/380 (48%), Gaps = 16/380 (4%) Query: 70 ASRQQLAKETSNFGFSLLRKISMRHDG-NMVFSPFGMSLAMTGLMLGATGPTETQIKRGL 128 A+ Q+ A+ + F ++ K+S + G N+VFSPF + LGA T TQ+ +GL Sbjct: 5 AAHQEFARRLALFSINVYGKLSGQKPGENIVFSPFSIQTCAAMARLGAENETATQLDQGL 64 Query: 129 HLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDT 188 L + P + + S + L + L + F+ + +++ F L + F + Sbjct: 65 GLASSDPEQ--IAHSFHQVLAAYQDSQI---LRIANKIFVMDGYQLRQEFDQLLSKQFLS 119 Query: 189 ECVPMNFRNASQAKRLMNHYINKETRGKIPKLF--DEINPETKLILVDYILFKGKWLTPF 246 ++F QA +N+++ + T I L D +N E++L+LV+ I FKG W F Sbjct: 120 AAQSVDFSKNVQAAATINNWVEQRTNHLIKDLVPADVLNSESRLVLVNAIHFKGTWQHQF 179 Query: 247 DPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQ-GNATMLVVLMEK 305 T DTFHLD +T++VPMM +F L+LPY+ + +ML+VL Sbjct: 180 AKHLTRPDTFHLDGERTVQVPMMSLKERFRYADLPALDAMALELPYKDSDLSMLIVLPNT 239 Query: 306 MGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFA 365 ALE+ L + +++ + + P+FK + + E+ E+ +++G+ R+FS A Sbjct: 240 KTGLPALEEKLRLTTLSQITQSLYETKVALKLPRFKAEFQVELSEVFQKLGMSRMFSDQA 299 Query: 366 DLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGI------LSEITAYSMPPVIKVDRP 419 + ++ + L+VS ++ + IEV+E GTEA A I + P D P Sbjct: 300 EFGKMLQSPEPLKVSAIIHKAFIEVNEEGTEAAAATGMAVRRKRAIMSPEEPIEFFADHP 359 Query: 420 FHFMIYEETSGMLLFLGRVV 439 F +++ + + LF G VV Sbjct: 360 FTYVLVHQKD-LPLFWGSVV 378 >2H4Q-A nrPDB Length = 382 Score = 140 bits (352), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 99/346 (28%), Positives = 171/346 (49%), Gaps = 20/346 (5%) Query: 68 LMASRQQLAKETSNFGFSLLRKIS-MRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKR 126 L S +Q++ NF L K++ D N+ FSP+ +S A+ L A G T ++ Sbjct: 38 LEISMEQVSASIGNFTVDLFNKLNETNRDKNIFFSPWSISSALALTYLAAKGSTAREMAE 97 Query: 127 GLHLQALKPTKPGL--LPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKR 184 LH + + G L + F R S L + ++ K + + T+ LSK+ Sbjct: 98 VLHFEQAENIHSGFKELLTAFNKPRNNYS------LRSANRIYVEKTYALLPTYLQLSKK 151 Query: 185 YFDTECVPMNFRNA-SQAKRLMNHYINKETRGKIPKLF--DEINPETKLILVDYILFKGK 241 Y+ E +NF+ A Q+++ +N ++ K+T KI L D++ T+LILV+ I FK + Sbjct: 152 YYKAEPQKVNFKTAPEQSRKEINTWVEKQTESKIKNLLSSDDVKATTRLILVNAIYFKAE 211 Query: 242 WLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPY-QGNATMLV 300 W F T + F L K K+ V MMY F + +++LPY + +M + Sbjct: 212 WEVKFQAEKTSIQPFRLSKNKSKPVKMMYMRDTFPVLIMEKMNFKMIELPYVKRELSMFI 271 Query: 301 VLMEKMGDHLA----LEDYLTTDLVETWL--RNMKTRNMEVFFPKFKLDQKYEMHELLRQ 354 +L + + D LE LT + + W + M +++ PKF L+ + ++ + LR Sbjct: 272 LLPDDIKDGTTGLEQLERELTYERLSEWADSKMMTETLVDLHLPKFSLEDRIDLRDTLRN 331 Query: 355 MGIRRIFSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAG 400 MG+ F+ AD ++ ++L +S+V+ ++ + VDE+GTEAVA Sbjct: 332 MGMTTAFTTNADFRGMT-DKKDLAISKVIHQSFVAVDEKGTEAVAA 376 >2R9Y-A nrPDB Length = 430 Score = 138 bits (347), Expect = 6e-33, Method: Compositional matrix adjust. Identities = 107/361 (29%), Positives = 175/361 (48%), Gaps = 19/361 (5%) Query: 84 FSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLPS 143 FSL+ + S N+V SP ++LA++ L LGA T + R LH+ P LL Sbjct: 33 FSLVAQTST--SSNLVLSPLSVALALSHLALGAQNQTLHSLHRVLHMNT-GSCLPHLLSH 89 Query: 144 LFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAKR 203 ++ L R + ++ K F +K+ F S+R F + V + + Sbjct: 90 FYQNLGPGTIR-------LAARIYLQKGFPIKDDFLEQSERLFGAKPVKLTGKQEEDLAN 142 Query: 204 LMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKT 263 + N ++ + T GKI E+ T L+L++ I F G W T FDP T+ D FHLD+ T Sbjct: 143 I-NQWVKEATEGKIEDFLSELPDSTVLLLLNAIHFHGFWRTKFDPSLTQKDFFHLDERFT 201 Query: 264 IKVPMMYGAGKFASTF-DKNFRCHVLKLPYQGNATMLVVLMEKMGDHLA-LEDYLTTDLV 321 + V MM+ F + V P++ N + +VV+ +++ + LT D + Sbjct: 202 VSVDMMHAVSYPLRWFLLEQPEIQVAHFPFKNNMSFVVVMPTYFEWNVSEVLANLTWDTL 261 Query: 322 ETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSR 381 + +++ R +V+ PK L Q+ ++ L Q+G++ +F DL +S +NL VS Sbjct: 262 --YHPSLQERPTKVWLPKLHLQQQLDLVATLSQLGLQELFQG-PDLRGISE--QNLVVSS 316 Query: 382 VLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYEETSGMLLFLGRVVNP 441 V ++ +E+ E G EA A + S+ V+RPF F I E+T G+ LF+G V NP Sbjct: 317 VQHQSTMELSEAGVEAAAATSVAMNRMSLSS-FTVNRPFLFFIMEDTIGVPLFVGSVRNP 375 Query: 442 T 442 Sbjct: 376 N 376 >6CJ7-A nrPDB Length = 390 Score = 136 bits (343), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 99/373 (26%), Positives = 189/373 (50%), Gaps = 15/373 (4%) Query: 79 TSNFGFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKP 138 +++FG ++ ++++ GN+ SPF +++ + L GA G T +I R L + K + Sbjct: 17 STSFGVNVFKQMATEQSGNLAASPFSITILLAMLQQGAAGNTLDEITRALQMTPEKSAE- 75 Query: 139 GLLPSLFKGLRETLS-RNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRN 197 +FK + E + RN L + F+ ++F++ F ++ FD++ P F Sbjct: 76 -----IFKKVNEEIQKRNSRNILKTANNVFLSENFNLNPQFKRIAVNNFDSDLTPTYFGK 130 Query: 198 ASQAKRLMNHYINKETRGKIPKLF--DEINPETKLILVDYILFKGKWLTPFDPVFTEVDT 255 + A + +N +I +T KI KL D+++ T++++V+ + FKG W PF T+ Sbjct: 131 PALAAQNINSWIASKTNDKIDKLVSPDDLSGNTQMVMVNAVYFKGLWEIPFREQATQKRN 190 Query: 256 FHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNA-TMLVVLMEKMGDHLALED 314 F L+ + M F + K V+ LP++ N +++VVL K + AL Sbjct: 191 FTLNGGEKKVASFMQTRRYFKAGTHKPAMAKVVVLPFEYNEYSLIVVLPLKSSNVDALLS 250 Query: 315 YLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATG 374 L+ + V ++L ++ +++ + PKF + + +L +MG+ IF+ A+L L + G Sbjct: 251 SLSMEDVASFL-DLPPKDVALELPKFSIKADINLEPVLNKMGVSSIFTQQAELYNLGSHG 309 Query: 375 R-NLQVSRVLQRTVIEVDERGTEAVAGILSEIT--AYSMPPV-IKVDRPFHFMIYEETSG 430 + QVS L V+ +DERG A A +Y P + + ++PF ++++ S Sbjct: 310 SLSPQVSSALHSAVLTIDERGGSAAAATSFAAVALSYDEPSLYFRANKPFLAILWDNRSS 369 Query: 431 MLLFLGRVVNPTL 443 + LF+ R+++PTL Sbjct: 370 IPLFMARIMDPTL 382 >1HLE-A nrPDB Length = 345 Score = 134 bits (337), Expect = 9e-32, Method: Compositional matrix adjust. Identities = 91/332 (27%), Positives = 174/332 (52%), Gaps = 19/332 (5%) Query: 73 QQLAKETSNFGFSLLRKISMRH-DGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQ 131 +QL+ ++F L R ++ GN+ SP +S A+ + LG G T Q+ + L+ Sbjct: 3 EQLSTANTHFAVDLFRALNESDPTGNIFISPLSISSALAMIFLGTRGNTAAQVSKALYFD 62 Query: 132 ALKPTKPGLLPSLFKGLRETLSR-NLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTEC 190 ++ + S F+ L +++ L + + K ++ F +++ + E Sbjct: 63 TVED-----IHSRFQSLNADINKPGAPYILKLANRLYGEKTYNFLADFLASTQKMYGAEL 117 Query: 191 VPMNFRNASQ-AKRLMNHYINKETRGKIPKLFDE--INPETKLILVDYILFKGKWLTPFD 247 ++F+ A + A++ +N ++ +T GKIP+L + ++ TKL+LV+ I FKG W F Sbjct: 118 ASVDFQQAPEDARKEINEWVKGQTEGKIPELLVKGMVDNMTKLVLVNAIYFKGNWQQKFM 177 Query: 248 PVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNA-TMLVVLMEKM 306 T F L+K T V MMY KF + ++ +C VL+LPYQG +M+++L + + Sbjct: 178 KEATRDAPFRLNKKDTKTVKMMYQKKKFPYNYIEDLKCRVLELPYQGKELSMIILLPDDI 237 Query: 307 GDHLA----LEDYLTTDLVETWLR--NMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRI 360 D +E LT D + W + N+ + V P+FKL++ Y++ L ++G++ + Sbjct: 238 EDESTGLEKIEKQLTLDKLREWTKPENLYLAEVNVHLPRFKLEESYDLTSHLARLGVQDL 297 Query: 361 FSPF-ADLSELSATGRNLQVSRVLQRTVIEVD 391 F+ ADLS +S R+L VS+++ ++ ++++ Sbjct: 298 FNRGKADLSGMSG-ARDLFVSKIIHKSFVDLN 328 >4DTE-A nrPDB Length = 374 Score = 133 bits (335), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 102/375 (27%), Positives = 183/375 (48%), Gaps = 24/375 (6%) Query: 80 SNFGFSLLRK-ISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQI--KRGLHLQALKPT 136 ++FG + + + D N+ SP+G++ + +GA G T + K G LQ Sbjct: 8 TDFGLQVFAEAVQSAPDRNLALSPYGIASVLGMAQMGAYGATLKLLASKMGYSLQERG-- 65 Query: 137 KPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFR 196 +P L + L+ L+ E G+ S + + +++ F + F + ++F Sbjct: 66 ----MPKLQRLLQRDLAS--EDGVEVASGVMVDRKIILEKVFRRSLSKAFQSVPHQIDFS 119 Query: 197 NASQAKRLMNHYINKETRGKIPKLFDE--INPETKLILVDYILFKGKWLTPFDPVFTEVD 254 A++++N + + T G I + ++ T+L+ ++ + F G W TPFDP T Sbjct: 120 QPEMARQVINSWTSDHTDGMISEFLPSGVLSELTRLVFLNALHFHGVWKTPFDPRNTREQ 179 Query: 255 TFHLDKYKTIKVPMM-----YGAGKFASTFDKNFRCHVLKLPYQGNAT--MLVVLMEKMG 307 FH + VPMM + G+F S ++ V+++PY+G + +LV EK Sbjct: 180 LFHTVNGSAVSVPMMTTTQKFNYGEFVSKDGVDY--DVIEMPYEGESISMLLVTPFEKDV 237 Query: 308 DHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFS-PFAD 366 AL L++ + W + M+ + ++ P+F +D + ++ L +MG+ IFS AD Sbjct: 238 PLSALNKELSSSRIHQWRQEMRKISKQLSIPRFSMDTEIDLKSTLSRMGLGDIFSQSRAD 297 Query: 367 LSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYE 426 S ++ T L VS+VLQR +EV+E GT+ + + I + I +DRPF F+I Sbjct: 298 FSRIT-TEEPLCVSKVLQRVKLEVNEEGTKGSSATAAVIYSRMAVEEITLDRPFFFLIQH 356 Query: 427 ETSGMLLFLGRVVNP 441 + +G LLF G++ P Sbjct: 357 KPTGALLFSGQLTQP 371 >2H4P-A nrPDB Length = 394 Score = 133 bits (335), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 100/369 (27%), Positives = 176/369 (47%), Gaps = 38/369 (10%) Query: 68 LMASRQQLAKETSNFGFSLLRKIS-MRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKR 126 L S +Q++ NF L K++ D N+ FSP+ +S A+ L A G T ++ Sbjct: 22 LEISMEQVSASIGNFTVDLFNKLNETNRDKNIFFSPWSISSALALTYLAAKGSTAREMAE 81 Query: 127 GLHLQAL--------------KPTKPGLLP------SLFKGLRETLS-----RNLELGLT 161 LH +P + + P ++ G +E L+ RN L Sbjct: 82 VLHFTEAVRAESSSVARPSRGRPKRRRMDPEHEQAENIHSGFKELLTAFNKPRN-NYSLR 140 Query: 162 QGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNA-SQAKRLMNHYINKETRGKIPKL 220 + ++ K + + T+ LSK+Y+ E +NF+ A Q+++ +N ++ K+T KI L Sbjct: 141 SANRIYVEKTYALLPTYLQLSKKYYKAEPQKVNFKTAPEQSRKEINTWVEKQTESKIKNL 200 Query: 221 F--DEINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFAST 278 D++ T+LILV+ I FK +W F T + F L K K+ V MMY F Sbjct: 201 LSSDDVKATTRLILVNAIYFKAEWEVKFQAEKTSIQPFRLSKNKSKPVKMMYMRDTFPVL 260 Query: 279 FDKNFRCHVLKLPY-QGNATMLVVLMEKMGDHLA----LEDYLTTDLVETWL--RNMKTR 331 + +++LPY + +M ++L + + D LE LT + + W + M Sbjct: 261 IMEKMNFKMIELPYVKRELSMFILLPDDIKDGTTGLEQLERELTYERLSEWADSKMMTET 320 Query: 332 NMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSRVLQRTVIEVD 391 +++ PKF L+ + ++ + LR MG+ F+ AD ++ ++L +S+V+ ++ + VD Sbjct: 321 LVDLHLPKFSLEDRIDLRDTLRNMGMTTAFTTNADFRGMT-DKKDLAISKVIHQSFVAVD 379 Query: 392 ERGTEAVAG 400 E+GTEA A Sbjct: 380 EKGTEAAAA 388 >6F4U-A nrPDB Length = 341 Score = 130 bits (328), Expect = 8e-31, Method: Compositional matrix adjust. Identities = 93/327 (28%), Positives = 164/327 (50%), Gaps = 14/327 (4%) Query: 74 QLAKETSNFGFSLLRKISMRHDG-NMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQA 132 ++A ++F F I+ G N+ FSP +S A L LGA + +QI GL Sbjct: 4 KIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNL 63 Query: 133 LKPTKPGLLPSLFKGLRETLS---RNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTE 189 + ++ + F+ L TL+ LE + GS F+ + F N + ++ + Sbjct: 64 TELSESDVHRG-FQHLLHTLNLPGHGLETRV--GSALFLSHNLKFLAKFLNDTMAVYEAK 120 Query: 190 CVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPV 249 NF + +L+N ++ KETRGKI L E+ + ++LV+YI FK W PF Sbjct: 121 LFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISS 180 Query: 250 FTEVDTFHLDKYKTIKVPMMYGAGKFASTF-DKNFRCHVLKLPYQGNATMLVVLMEKMGD 308 T F++D+ T++VPMM + D+ C VL++ Y+G+AT+ +L + G Sbjct: 181 RTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQ-GK 239 Query: 309 HLALEDYLTTDLVETWLRNMKTRN----MEVFFPKFKLDQKYEMHELLRQMGIRRIFSPF 364 +E+ LT +++ W ++ RN +E+ PKF + Y + ++L ++G +FS + Sbjct: 240 MREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKW 299 Query: 365 ADLSELSATGRNLQVSRVLQRTVIEVD 391 ADLS ++ + L+ S+ + ++VD Sbjct: 300 ADLSGITKQ-QKLEASKSFHKATLDVD 325 >4ZK0-A nrPDB Length = 390 Score = 129 bits (325), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 108/390 (27%), Positives = 192/390 (49%), Gaps = 26/390 (6%) Query: 75 LAKETSNFGFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALK 134 L++ + F F L ++ + N+ +SP ++ A+ ++LGA T QIK+ LH + Sbjct: 4 LSEANTKFMFDLFQQFRKSKENNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHFDQVT 63 Query: 135 PTKPGLLPSLFKGLRETLSRNLELGLTQ------------GSFAFIHKDFDVKETFFNLS 182 G + + + LT+ + F K + + + + Sbjct: 64 ENTTGKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYLFLQEYLDAI 123 Query: 183 KRYFDTECVPMNFRNA-SQAKRLMNHYINKETRGKIPKLFDE--INPETKLILVDYILFK 239 K+++ T ++F NA ++++ +N ++ +T KI L E I T L+LV+ I FK Sbjct: 124 KKFYQTSVESVDFANAPEESRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVNAIYFK 183 Query: 240 GKWLTPFDPVFTEVDTFHLDK--YKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNAT 297 G+W F+ T+ + F +K YK+I++ Y + FAS D + VL++PY+G Sbjct: 184 GQWEKKFNKEDTKEEKFWPNKNTYKSIQMMRQYTSFHFASLED--VQAKVLEIPYKGKDL 241 Query: 298 MLVVLMEKMGDHL-ALEDYLTTDLVETW--LRNMKTRNMEVFFPKFKLDQKYEMHELLRQ 354 ++VL+ D L LE+ LT + + W L+NM+ +++ P+FK+++ Y++ + LR Sbjct: 242 SMIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRETRVDLHLPRFKVEESYDLKDTLRT 301 Query: 355 MGIRRIFSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEI---TAYSMP 411 MG+ IF+ ADLS ++ + R L +S VL + +EV E G EA A + S Sbjct: 302 MGMVDIFNGDADLSGMTGS-RGLVLSGVLHKAFVEVTEEGAEAAAATAVVGFGSSPTSTN 360 Query: 412 PVIKVDRPFHFMIYEETSGMLLFLGRVVNP 441 + PF F I + + +LF GR +P Sbjct: 361 EEFHCNHPFLFFIRQNKTNSILFYGRFSSP 390 >3PZF-A nrPDB Length = 397 Score = 126 bits (317), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 99/382 (25%), Positives = 181/382 (47%), Gaps = 17/382 (4%) Query: 76 AKETSNFGFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGAT----GPTETQIKRGLHLQ 131 + + F +++I H+ N+V SPF + + +T L+ A+ G + KR L Sbjct: 19 GQRQNEFDLMFVKEIFKNHNSNVVLSPFSVKILLT-LIYEASDTSFGNAVSNTKRELS-S 76 Query: 132 ALKPTKPGLLPSLFKGLRETLSR-NLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTEC 190 ++ S +K L E+ + N + L + F+ +V + ++ ++ Sbjct: 77 VIQNDNIDHTRSYYKQLLESAQQDNKDYDLNIATNFFVDDFIEVINKYQQIANTHYHAML 136 Query: 191 VPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLI-LVDYILFKGKWLTPFDPV 249 +++ N +Q +N+++++ T G++ ++ + E +I LV+ I FKG W PF V Sbjct: 137 EKVSYSNPTQTAATINNWVSEHTNGRLREIVTPDSLEGAVITLVNVIYFKGLWTYPFPEV 196 Query: 250 FTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDH 309 V F+ + K M G+F + +L+LPY+GN + ++ + Sbjct: 197 ANNVKPFYGTRGKPTNAQYMEQNGQFYYDNSADLGAQILRLPYRGNKLAMYFILPNPDNT 256 Query: 310 L-ALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLS 368 + + D + + + L M+ + V PKFK D +++E L+Q+GIR IFS A L Sbjct: 257 VNQVLDRINSASLHQALWYMEENEVNVTLPKFKFDFSEQLNEPLQQVGIREIFSQNASLP 316 Query: 369 ELSATGRN----LQVSRVLQRTVIEVDERGTEAVAGILSEIT---AYSMPPVIKVDRPFH 421 L A GR ++VSR+ Q+ I ++E G+EA A ++ + +RPF Sbjct: 317 -LLARGRGARDEVRVSRIFQKAGITINELGSEAYAATEIQLVNKFGGDGVQIFNANRPFI 375 Query: 422 FMIYEETSGMLLFLGRVVNPTL 443 F I +ET G +LF G++ NP Sbjct: 376 FFIEDETLGTMLFAGKIENPVF 397 >3ZHA-A nrPDB Length = 392 Score = 119 bits (299), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 93/371 (25%), Positives = 176/371 (47%), Gaps = 8/371 (2%) Query: 75 LAKETSNFGFSLLRKISMRHD-GNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQAL 133 LA+ ++ FSL + ++ N++ SP ++ ++ + LG T +Q K L + L Sbjct: 9 LAERSAGLAFSLYQAMAKDQAVENILLSPVVVASSLGLVSLGGKATTASQAKAVLSAEQL 68 Query: 134 KPTK-PGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVP 192 + + L L + L + +RN+ L GS + E F SK++++ E Sbjct: 69 RDEEVHAGLGELLRSLSNSTARNVTWKL--GSRLYGPSSVSFAEDFVRSSKQHYNCEHSK 126 Query: 193 MNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTE 252 +NFR+ A + +N + + T GK+P++ ++ +LV+ + FK W F + Sbjct: 127 INFRDKRSALQSINEWAAQTTDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVD 186 Query: 253 VDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLA- 311 F + + T+ V MM+ G + D+ + ++++P + L++LM + L Sbjct: 187 NRGFMVTRSYTVGVTMMHRTGLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLER 246 Query: 312 LEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGI-RRIFSPFADLSEL 370 LE LT + ++ W+ M+ + + + PK ++ +++ + L +G+ I ADLS + Sbjct: 247 LEKLLTKEQLKIWMGKMQKKAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRM 306 Query: 371 SATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYEETSG 430 S ++L ++ V T E D G I S P + D PF F++ + SG Sbjct: 307 SGK-KDLYLASVFHATAFEWDTEGNPFDQDIYGREELRS-PKLFYADHPFIFLVRDTQSG 364 Query: 431 MLLFLGRVVNP 441 LLF+GR+V P Sbjct: 365 SLLFIGRLVRP 375 >1SEK-A nrPDB Length = 378 Score = 119 bits (299), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 105/381 (27%), Positives = 189/381 (49%), Gaps = 22/381 (5%) Query: 73 QQLAKETSN-FGFSLLRKISMRHDG-NMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHL 130 Q++ +E+++ F + ++ + G N+V S F + + L L + G + ++ R L L Sbjct: 8 QKILRESNDQFTAQMFSEVVKANPGQNVVLSAFSVLPPLGQLALASVGESHDELLRALAL 67 Query: 131 QALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTEC 190 TK + L +G+R +L++ S ++ K ++ + F +S+ F +E Sbjct: 68 PNDNVTK-DVFADLNRGVRAVKGVDLKMA----SKIYVAKGLELNDDFAAVSRDVFGSEV 122 Query: 191 VPMNFRNASQAKRLMNHYINKETRGKIPKLFD--EINPETKLILVDYILFKGKWLTPFDP 248 ++F + +A +N ++ +T +I L D ++ T+ +LV+ I FKG W F+ Sbjct: 123 QNVDFVKSVEAAGAINKWVEDQTNNRIKNLVDPDALDETTRSVLVNAIYFKGSWKDKFNK 182 Query: 249 VFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGN-ATMLVVLMEKMG 307 T FH+ K KTIKVP M G ++++ Y+G+ A+M+++L ++ Sbjct: 183 ERTMDRDFHVSKDKTIKVPTMIGKKDVRYADVPELDAKMIEMSYEGDQASMIIILPNQVD 242 Query: 308 DHLALEDYL----TTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSP 363 ALE L E L N + +E++ PKFK++ ++ E+L M I+++F+P Sbjct: 243 GITALEQKLKDPKALSRAEERLYNTE---VEIYLPKFKIETTTDLKEVLSNMNIKKLFTP 299 Query: 364 -FADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMP--PVIKVDRPF 420 A L L T +L V +Q+ IEV+E G EA A +IT YS P +++++PF Sbjct: 300 GAARLENLLKTKESLYVDAAIQKAFIEVNEEGAEAAAANAFKITTYSFHFVPKVEINKPF 359 Query: 421 HFMIYEETSGMLLFLGRVVNP 441 F + + M F G V P Sbjct: 360 FFSLKYNRNSM--FSGVCVQP 378 >2OAY-A nrPDB Length = 390 Score = 118 bits (296), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 99/367 (26%), Positives = 178/367 (48%), Gaps = 32/367 (8%) Query: 83 GFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLP 142 FS ++K+ + NM FSPF ++ +T ++LGA T+T ++ L P Sbjct: 46 AFSAMKKV----ETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSY-----------P 90 Query: 143 SLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAK 202 F + + L G+T S F D +++TF N S+ + + P N S A Sbjct: 91 KDFTCVHQALKGFTTKGVTSVSQIFHSPDLAIRDTFVNASRTLYSSS--PRVLSNNSDAN 148 Query: 203 -RLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKY 261 L+N ++ K T KI +L D + +T+L+L++ I KW T FDP T ++ FH K Sbjct: 149 LELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKTTFDPKKTRMEPFHF-KN 207 Query: 262 KTIKVPMMYGAGKF--ASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLA-LEDYLTT 318 IKVPMM + K+ A D+ + V +L N ++++++ + + L +E L+ Sbjct: 208 SVIKVPMM-NSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVPQNLKHRLEDMEQALSP 266 Query: 319 DLVETWLRNMKTRNME---VFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSAT-G 374 + + + ++ + + P+ K+ +M ++ ++ F DL+ T Sbjct: 267 SVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKL---EFFDFSYDLNLCGLTED 323 Query: 375 RNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYEETSGMLLF 434 +LQVS + +TV+E+ E G EA A + + V +V +PF FM++++ +F Sbjct: 324 PDLQVSAMQHQTVLELTETGVEAAAASAISVARTLL--VFEVQQPFLFMLWDQQHKFPVF 381 Query: 435 LGRVVNP 441 +GRV +P Sbjct: 382 MGRVYDP 388 >1K9O-I nrPDB Length = 378 Score = 118 bits (296), Expect = 5e-27, Method: Compositional matrix adjust. Identities = 105/381 (27%), Positives = 189/381 (49%), Gaps = 22/381 (5%) Query: 73 QQLAKETSN-FGFSLLRKISMRHDG-NMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHL 130 Q++ +E+++ F + ++ + G N+V S F + + L L + G + ++ R L L Sbjct: 8 QKILRESNDQFTAQMFSEVVKANPGQNVVLSAFSVLPPLGQLALASVGESHDELLRALAL 67 Query: 131 QALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTEC 190 TK + L +G+R +L++ S ++ K ++ + F +S+ F +E Sbjct: 68 PNDNVTK-DVFADLNRGVRAVKGVDLKMA----SKIYVAKGLELNDDFAAVSRDVFGSEV 122 Query: 191 VPMNFRNASQAKRLMNHYINKETRGKIPKLFD--EINPETKLILVDYILFKGKWLTPFDP 248 ++F + +A +N ++ +T +I L D ++ T+ +LV+ I FKG W F Sbjct: 123 QNVDFVKSVEAAGAINKWVEDQTNNRIKNLVDPDALDETTRSVLVNAIYFKGSWKDKFVK 182 Query: 249 VFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGN-ATMLVVLMEKMG 307 T FH+ K KTIKVP M G ++++ Y+G+ A+M+++L ++ Sbjct: 183 ERTMDRDFHVSKDKTIKVPTMIGKKDVRYADVPELDAKMIEMSYEGDQASMIIILPNQVD 242 Query: 308 DHLALEDYL----TTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSP 363 ALE L E L N + +E+ PKFK++ ++ E+L M I+++F+P Sbjct: 243 GITALEQKLKDPKALSRAEERLYNTE---VEITLPKFKIETTTDLKEVLSNMNIKKLFTP 299 Query: 364 -FADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMP--PVIKVDRPF 420 A L L T +L V +Q+ IEV+E G EA A I S+ P + +DRPF Sbjct: 300 GAARLENLLKTKESLTVDAAIQKAFIEVNEEGAEAAAANAFGIVPKSLILYPEVHIDRPF 359 Query: 421 HFMIYEETSGMLLFLGRVVNP 441 +F + + G+ +F G+V+ P Sbjct: 360 YFEL--KIDGIPMFNGKVIEP 378 >1JJO-C nrPDB Length = 261 Score = 118 bits (295), Expect = 6e-27, Method: Compositional matrix adjust. Identities = 69/246 (28%), Positives = 128/246 (52%), Gaps = 16/246 (6%) Query: 167 FIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINP 226 F+ F V E F + K YF+ E ++F +N ++ T + L ++P Sbjct: 13 FVQNGFHVNEEFLQMLKMYFNAEVNHVDFSQNVAVANSINKWVENYTNSLLKDL---VSP 69 Query: 227 E-----TKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKF------ 275 E T L L++ + FKG W + F P T +F D +++PMMY G+F Sbjct: 70 EDFDGVTNLALINAVYFKGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFS 129 Query: 276 ASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLA-LEDYLTTDLVETWLRNMKTRNME 334 + + VL++PY+G+ +++ + + LA LE L L+E W ++K + +E Sbjct: 130 DGSNEAGGIYQVLEIPYEGDEISMMLALSRQEVPLATLEPLLKAQLIEEWANSVKKQKVE 189 Query: 335 VFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSRVLQRTVIEVDERG 394 V+ P+F ++Q+ ++ ++L+ +G+ IF A+L+ +S + L +S+ + ++ IEV+E G Sbjct: 190 VYLPRFTVEQEIDLKDILKALGVTEIFIKDANLTAMS-DKKELFLSKAVHKSCIEVNEEG 248 Query: 395 TEAVAG 400 +EA A Sbjct: 249 SEAAAA 254 >5NCS-A nrPDB Length = 375 Score = 115 bits (289), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 99/378 (26%), Positives = 178/378 (47%), Gaps = 42/378 (11%) Query: 82 FGFSLLRKISMRH--DGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLH-----LQALK 134 F F LL+ + +H + N+ SP +S+A+ + GA G T ++K L ++ + Sbjct: 14 FAFDLLQ-TTRKHVTEANVFISPLSVSMALNMTLNGAAGVTADEMKTALRETGYTMEDIN 72 Query: 135 PTKPGLLPSLFK-GLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPM 193 L +L K T+ + QG VKE F ++ ++D E + Sbjct: 73 EYSHSLREALLKVDPSTTIGMANSIWYKQGEL--------VKEPFILANRTHYDAEVKAV 124 Query: 194 NFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTEV 253 +F + + + N + ++T KI K+ D I + L++ + FKG W+T F T+ Sbjct: 125 DFSSPATLPAI-NGWCAQKTNDKITKILDYIPGNAFMYLINAVYFKGIWVTQFKKSDTKR 183 Query: 254 DTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLALE 313 F T +V MM F T D+ C L++ Y A ++V++ G Sbjct: 184 APFRKADGTTQEVNMMAQKSTFGYTTDEC--CQYLEMDYGNKAFSMIVMLPNEGQ----- 236 Query: 314 DYLTTDLVET-----W---LRNMKTRNMEVFFPKFKLDQKYEMH-ELLRQMGIRRIFSPF 364 T D++E W ++ ++ + + P+FK + KY + ++L +MG+ F+ Sbjct: 237 --TTRDVIEQLDNKHWSMIIKGIRPTQVSLRMPRFKTECKYGLEKKILPEMGMNVPFTET 294 Query: 365 ADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMP---PV-IKVDRPF 420 AD + T + +SRV+ +T ++VDE GTEA A E+ S P P+ +++PF Sbjct: 295 ADFPGI--TDAAIFISRVIHKTFVQVDEEGTEAAAVTAVEMVKTSSPSTTPINFHINKPF 352 Query: 421 HFMIYEETSGMLLFLGRV 438 F I E+++G++LF+G + Sbjct: 353 VFAIREKSTGVILFIGEI 370 >6BJ5-B nrPDB Length = 315 Score = 112 bits (279), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 93/322 (28%), Positives = 153/322 (47%), Gaps = 35/322 (10%) Query: 81 NFGFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGL 140 + G R + D N+VFSP+G++ A++ L + A G T+ +I P Sbjct: 17 DIGLWTFRYVYNESD-NVVFSPYGLTSALSVLRIAAGGNTKREID--------VPESVVE 67 Query: 141 LPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQ 200 F LRE F+ ++ F F+T + F N+ Sbjct: 68 DSDAFLALRE---------------LFVDASVPLRPEFTAEFSSRFNTSVQRVTF-NSEN 111 Query: 201 AKRLMNHYINKETRGKIPKLFD-EINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLD 259 K ++N Y+ +T G +P++ D ++ +TK++L+ + K W FDP FT F+ Sbjct: 112 VKDVINSYVKDKTGGDVPRVLDASLDRDTKMLLLSSVRMKTSWRHVFDPSFTTDQPFYSG 171 Query: 260 KYKTIKVPMMYGAGKFAS-TFD-KNFRCHVLKLPYQGNAT-MLVVLMEKMGDHLALEDYL 316 T KV MM + TF +N V +LPY+ T ML+V+ + +G+ + D Sbjct: 172 NV-TYKVRMMNKIDTLKTETFTLRNVGYSVTELPYKRRQTAMLLVVPDDLGEIVRALDL- 229 Query: 317 TTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPF-ADLSELSATGR 375 LV W+RNM+ +V PKF ++ ++ + L+++G+R F P AD + S + Sbjct: 230 --SLVRFWIRNMRKDVCQVVMPKFSVESVLDLRDALQRLGVRDAFDPSRADFGQASPSN- 286 Query: 376 NLQVSRVLQRTVIEVDERGTEA 397 +L V++VLQ + IE DERGT A Sbjct: 287 DLYVTKVLQTSKIEADERGTTA 308 >1C8O-A nrPDB Length = 300 Score = 110 bits (275), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 87/320 (27%), Positives = 153/320 (47%), Gaps = 31/320 (9%) Query: 86 LLRKISMRHDGNMVF-SPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLPSL 144 + R+I+ G VF SP +S +T L GA G T Q+ + + +A K S+ Sbjct: 3 IFREIASSMKGENVFISPPSISSVLTILYYGANGSTAEQLSKYVEKEADKNKDDISFKSM 62 Query: 145 FKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAKRL 204 K G ++ + KD +F F T ++F + S+ Sbjct: 63 NK--------------VYGRYSAVFKD-----SFLRKIGDNFQT----VDFTD-SRTVDA 98 Query: 205 MNHYINKETRGKIPKLFDE-INPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKT 263 +N ++ T GKI L DE ++P+T L+ + + FK KWL PF+ FT F++ + Sbjct: 99 INKSVDIFTEGKINPLLDEPLSPDTSLLAISAVYFKAKWLMPFEKEFTSDYPFYVSPTEM 158 Query: 264 IKVPMM--YGAGKFASTFDKNF-RCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLTTDL 320 + V MM YG ++ ++F +++LPY G+ +M+V+L + + ++E LT Sbjct: 159 VDVSMMSMYGEAFNHASVKESFGNFSIIELPYVGDTSMVVILPDNIDGLESIEQNLTDTN 218 Query: 321 VETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVS 380 + W +M ++V PKFK+ Y + + L ++G+ +F D S +S ++ V Sbjct: 219 FKKWSDSMDAMFIDVHIPKFKVTGSYNLVDALVKLGLTEVFGSTGDYSNMS--NSDVSVD 276 Query: 381 RVLQRTVIEVDERGTEAVAG 400 ++ +T I+V+E TEA A Sbjct: 277 AMIHKTYIDVNEEYTEAAAA 296 >3LE2-A nrPDB Length = 393 Score = 109 bits (272), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 105/380 (27%), Positives = 175/380 (46%), Gaps = 43/380 (11%) Query: 91 SMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRE 150 ++ + N++FSP +++ ++ + G+ G T+ QI L LK + L S + Sbjct: 26 TVSQNSNVIFSPASINVVLSIIAAGSAGATKDQI-----LSFLKFSSTDQLNSFSSEIVS 80 Query: 151 TL----SRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRN-ASQAKRLM 205 + S N L+ + A+I K K +F L + + +F++ A + + Sbjct: 81 AVLADGSANGGPKLSVANGAWIDKSLSFKPSFKQLLEDSYKAASNQADFQSKAVEVIAEV 140 Query: 206 NHYINKETRGKIPKLFDEINPE--TKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKT 263 N + KET G I ++ E + + TKLI + + FKG W FD T+ FHL Sbjct: 141 NSWAEKETNGLITEVLPEGSADSMTKLIFANALYFKGTWNEKFDESLTQEGEFHLLDGNK 200 Query: 264 IKVPMMYGAGK-FASTFDKNFRCHVLKLPY-QGNATMLVVLMEKMGD-HLALEDYL---- 316 + P M K + S +D F+ VL LPY QG + + D + L D L Sbjct: 201 VTAPFMTSKKKQYVSAYD-GFK--VLGLPYLQGQDKRQFSMYFYLPDANNGLSDLLDKIV 257 Query: 317 -TTDLVETWL--RNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSAT 373 T ++ + R +K R ++ PKFK ++ +L+ +G+ FS L+E+ + Sbjct: 258 STPGFLDNHIPRRQVKVREFKI--PKFKFSFGFDASNVLKGLGLTSPFSGEEGLTEMVES 315 Query: 374 ---GRNLQVSRVLQRTVIEVDERGTEAVA---------GILSEITAYSMPPVIKVDRPFH 421 G+NL VS + + IEV+E GTEA A G+L E D PF Sbjct: 316 PEMGKNLCVSNIFHKACIEVNEEGTEAAAASAGVIKLRGLLMEEDEIDFV----ADHPFL 371 Query: 422 FMIYEETSGMLLFLGRVVNP 441 ++ E +G++LF+G+VV+P Sbjct: 372 LVVTENITGVVLFIGQVVDP 391 >1XQJ-A nrPDB Length = 389 Score = 108 bits (270), Expect = 5e-24, Method: Compositional matrix adjust. Identities = 90/390 (23%), Positives = 181/390 (46%), Gaps = 19/390 (4%) Query: 64 EKAWLMASRQQLAKETSNFGFSLLRKISMRHD-GNMVFSPFGMSLAMTGLMLGATGPTET 122 E + S L S F L +++S + GN++FSP +S +++ +GA G T Sbjct: 7 ENLYFQGSMDALQLANSAFAVDLFKQLSEKEPLGNVLFSPIALSTSLSLAQVGAKGDTAN 66 Query: 123 QIKRGLHLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLS 182 +I + LH + +K G LS L L + ++ K ++ F + + Sbjct: 67 EIGQVLHFENVKDVPFGF--QTVTSDVNKLSSFYSLKLIKR--LYVDKSLNLSTEFISST 122 Query: 183 KRYFDTECVPMNFRNA-SQAKRLMNHYINKETRGKIPKLF--DEINPETKLILVDYILFK 239 KR + E ++F++ + K +N+ I T G + + +N +TK+++V+ F Sbjct: 123 KRPYAKELETVDFKDKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFV 182 Query: 240 GKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQG-NATM 298 GKW+ F T+ F ++K T V MM F+ + +++LP+Q + +M Sbjct: 183 GKWMKKFSESETKESPFRVNKTDTKPVQMMNMEATFSMGNIDSINSKIIELPFQNKHLSM 242 Query: 299 LVVLMEKMGDHLA----LEDYLTTDLVETWLR--NMKTRNMEVFFPKFKLDQKYEMHELL 352 ++L + + D +E L ++ + W M +++ PKFK+++ + L Sbjct: 243 FILLPKDVEDESTGLEKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDPKASL 302 Query: 353 RQMGIRRIFS-PFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMP 411 +G++ IFS +D S +S T + + +S V+ + +E+ E G +++ + I + Sbjct: 303 ENLGLKHIFSEDTSDFSGMSET-KGVALSNVIHKVSLEITEDGGDSIEVPGARILQHK-- 359 Query: 412 PVIKVDRPFHFMIYEETSGMLLFLGRVVNP 441 + D PF ++I + ++F G+ +P Sbjct: 360 DELNADHPFIYIIRHNKTRNIIFFGKFSSP 389 >1M93-B nrPDB Length = 245 Score = 101 bits (252), Expect = 6e-22, Method: Compositional matrix adjust. Identities = 61/206 (29%), Positives = 110/206 (53%), Gaps = 6/206 (2%) Query: 199 SQAKRLMNHYINKETRGKIPKLFDE-INPETKLILVDYILFKGKWLTPFDPVFTEVDTFH 257 S+ +N ++ T GKI L DE ++P+T L+ + + FK KWL PF+ FT F+ Sbjct: 38 SRTVDAINKSVDIFTEGKINPLLDEPLSPDTSLLAISAVYFKAKWLMPFEKEFTSDYPFY 97 Query: 258 LDKYKTIKVPMM--YGAGKFASTFDKNF-RCHVLKLPYQGNATMLVVLMEKMGDHLALED 314 + + + V MM YG ++ ++F +++LPY G+ +M+V+L + + ++E Sbjct: 98 VSPTEMVDVSMMSMYGEAFNHASVKESFGNFSIIELPYVGDTSMVVILPDNIDGLESIEQ 157 Query: 315 YLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATG 374 LT + W +M ++V PKFK+ Y + + L ++G+ +F D S +S Sbjct: 158 NLTDTNFKKWSDSMDAMFIDVHIPKFKVTGSYNLVDALVKLGLTEVFGSTGDYSNMS--N 215 Query: 375 RNLQVSRVLQRTVIEVDERGTEAVAG 400 ++ V ++ +T I+V+E TEA A Sbjct: 216 SDVSVDAMIHKTYIDVNEEYTEAAAA 241 >2PEF-A nrPDB Length = 373 Score = 101 bits (252), Expect = 6e-22, Method: Compositional matrix adjust. Identities = 98/388 (25%), Positives = 171/388 (44%), Gaps = 45/388 (11%) Query: 73 QQLAKETSNFGFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQA 132 ++ T++F L + S+ N + SP LA+ GA T Q+++ L Sbjct: 7 EKFIYNTADFSIELFKN-SIDDKENSLISPLSAMLALAMTANGADNETLAQMEKALGKDI 65 Query: 133 LKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVP 192 L + K L L + S F DF + F + Y+ + Sbjct: 66 SIEDLNKYLYTYMKKLPNEEKSKLTIA---NSIWFKENDFMPSKDFLQIIADYYKADIFK 122 Query: 193 MNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTE 252 F +++ + +N+++ +T G I K+ ++I+PE + L++ + F +W T ++ Sbjct: 123 AAFDSSTVSD--INNWVKSKTNGMIDKILNKIDPEDVMYLINAVAFDAEWETVYEKASVH 180 Query: 253 VDTFHLDKYKT-IKVPMM------YGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEK 305 D F D Y KV M Y + A F K PY N V ++ Sbjct: 181 EDIF-TDVYGNRQKVEFMNSEENLYIEEENAVGFVK---------PYAKNHYSFVAILP- 229 Query: 306 MGDHLALEDYLTT-------DLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIR 358 +++++ +Y+ T DL+ +N K + PKFK + +M+E L +G+ Sbjct: 230 -DENISVNEYIKTLTGQKFIDLI----KNAKITLVRASLPKFKYEYTIKMNETLESLGMT 284 Query: 359 RIFSPFADLSELSATGR----NLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMP--- 411 F P D ++ S G+ NL +S VL +T I VDE GT+A A +ITA +P Sbjct: 285 DAFLP--DKADFSKLGKSDIGNLYISEVLHKTFISVDELGTKAGAVTSVDITAAGIPVNF 342 Query: 412 PVIKVDRPFHFMIYEETSGMLLFLGRVV 439 +K++RPF F I + ++ + +F+G V+ Sbjct: 343 KTVKLNRPFIFAIIDNSTNLPIFIGTVL 370 >3STO-A nrPDB Length = 406 Score = 99.0 bits (245), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 94/385 (24%), Positives = 179/385 (46%), Gaps = 25/385 (6%) Query: 82 FGFSLLRKISMRHDG-NMVFSPFGMSLAMTGLMLG---ATGPTETQIKRGLHLQALKPTK 137 F + L ++ G N + P G+ + G++LG A G T QI + + L++ + Sbjct: 22 FTHAYLSTVTADFGGDNFLTCPLGILFTL-GILLGSGGAQGRTGYQIGKTMRLKSTSSSW 80 Query: 138 PGL-----LPSLFKGLRETLS-------RNLELGLTQGSFAFIHKDFDVKETFFNLSKRY 185 + SL++ L +L+ E + + F+ K ++V+ F Sbjct: 81 NSSEAQQEMKSLYQELNNSLTSEKTFLNEKEENVVRISTGIFVEKTYEVERRFNESIAND 140 Query: 186 FDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLF-DEINPETKLILVDYILFKGKWLT 244 + E ++F N + A +N ++++++ G + K F D+I +T +ILV+ F+ W + Sbjct: 141 SEGELKQVDFSNRTSATVDINDWVDQQSNGLLEKFFTDDIPDDTAMILVNVFYFRDFWQS 200 Query: 245 PFDPVFTEVDTFHLDKYKTIKVPMMYGAG--KFASTFDKNFRCHVLKLPYQGNATMLVVL 302 PF+P +T + F++ + I V MM G K+ D+ F L ++V+ Sbjct: 201 PFEPHYTRKEDFYISPDRQITVDMMTQEGVMKYGKFEDEGFEIVSKPLNNTRFTFVIVLP 260 Query: 303 MEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFS 362 +EK + A E ++ +++N+K + + PKF L ++ L+ +G+ +F Sbjct: 261 LEKWSLNGATELLNGNKVLSEYVKNLKETTVSLRLPKFTLKNTLDLVPTLKSIGVVDLFD 320 Query: 363 PF-ADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYS--MPPV-IKVDR 418 P +DLS ++ NL V+ +Q V++++E G EA +S +P V V Sbjct: 321 PVKSDLSGITP-NPNLYVNEFIQTNVLKLNESGIEATTVTSPIFVPFSAIIPEVDFHVTH 379 Query: 419 PFHFMIYEETSGMLLFLGRVVNPTL 443 PF IY++ M + +V+NP L Sbjct: 380 PFICFIYDQQLTMPIMAAKVMNPVL 404 >1SNG-A nrPDB Length = 370 Score = 97.4 bits (241), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 94/369 (25%), Positives = 168/369 (45%), Gaps = 31/369 (8%) Query: 82 FGFSLLRKIS-MRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGL 140 F L R+++ DG +++SP+ ++ A+ L GA T T++ L L Sbjct: 17 FALHLHRRLAEAVPDGEVIWSPYSVACALGVLAAGARATTRTELTTLLGTDPAP-----L 71 Query: 141 LPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFR-NAS 199 L +L + + ++ L + ++ D V+ +F D++ +FR N Sbjct: 72 LAALDRAVTDSPD------LASRTVLWVSADVPVRSSFRATMHDRPDSDVRTADFRTNPE 125 Query: 200 QAKRLMNHYINKETRGKIPKLFDE--INPETKLILVDYILFKGKWLTPFDPVFTEVDTFH 257 + +N I TRG I +L + + P+ + IL + + K +W TPF+ T TF Sbjct: 126 GVRATVNADIADATRGMIRELLPQGAVTPDLRAILTNALWAKARWTTPFEAHLTRAGTFR 185 Query: 258 LDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLT 317 + +VP M+ + +R L + + + VL+ + A+ T Sbjct: 186 TPRGPK-RVPFMHRTKTMPYATARGWRMVTL---HAHDELAVDVLLPPGTNAAAVP---T 238 Query: 318 TDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNL 377 L+ R + ++E+ P+F+L Q +++ E+L + G+R +F+ ADLS +S L Sbjct: 239 APLLTALHRRSASTSVELALPRFELTQPHQLVEVLAEAGVRTLFTASADLSGISTV--PL 296 Query: 378 QVSRVLQRTVIEVDERGTEAVAGILSEITAY-SMPP----VIKVDRPFHFMIYEETSGML 432 V V+ + + VDERG E A + + +MPP VDRPFH ++ G + Sbjct: 297 YVDTVIHQARLRVDERGAEGAAATAAMMLLAGAMPPRRTIRFSVDRPFHIVVRRR--GAI 354 Query: 433 LFLGRVVNP 441 LFLG + +P Sbjct: 355 LFLGSIADP 363 >5NCU-A nrPDB Length = 336 Score = 94.7 bits (234), Expect = 6e-20, Method: Compositional matrix adjust. Identities = 86/335 (25%), Positives = 153/335 (45%), Gaps = 38/335 (11%) Query: 82 FGFSLLRKISMRH--DGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLH-----LQALK 134 F F LL+ + +H + N+ SP +S+A+ + GA G T ++K L ++ + Sbjct: 14 FAFDLLQ-TTRKHVTEANVFISPLSVSMALNMTLNGAAGVTADEMKTALRETGYTMEDIN 72 Query: 135 PTKPGLLPSLFK-GLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPM 193 L +L K T+ + QG VKE F ++ ++D E + Sbjct: 73 EYSHSLREALLKVDPSTTIGMANSIWYKQGEL--------VKEPFILANRTHYDAEVKAV 124 Query: 194 NFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTEV 253 +F + + + N + ++T KI K+ D I + L++ + FKG W+T F T+ Sbjct: 125 DFSSPATLPAI-NGWCAQKTNDKITKILDYIPGNAFMYLINAVYFKGIWVTQFKKSDTKR 183 Query: 254 DTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLALE 313 F T +V MM F T D+ C L++ Y A ++V++ G Sbjct: 184 APFRKADGTTQEVNMMAQKSTFGYTTDEC--CQYLEMDYGNKAFSMIVMLPNEGQ----- 236 Query: 314 DYLTTDLVET-----W---LRNMKTRNMEVFFPKFKLDQKYEMH-ELLRQMGIRRIFSPF 364 T D++E W ++ ++ + + P+FK + KY + ++L +MG+ F+ Sbjct: 237 --TTRDVIEQLDNKHWSMIIKGIRPTQVSLRMPRFKTECKYGLEKKILPEMGMNVPFTET 294 Query: 365 ADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVA 399 AD + T + +SRV+ +T ++VDE GTEA A Sbjct: 295 ADFPGI--TDAAIFISRVIHKTFVQVDEEGTEAAA 327 >2WXX-A nrPDB Length = 453 Score = 86.7 bits (213), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 106/445 (23%), Positives = 186/445 (41%), Gaps = 42/445 (9%) Query: 20 PGLAPSPQSPETPAP-QNQTSRVVQAPKEEEEDEQEASEEKASEEEKAWLMASRQQLAKE 78 P + P+S P P Q +TS V + + D+ + EK +E++ Q+A Sbjct: 24 PSVETLPESTFEPVPIQAKTSPVNE---KTLHDQLVLAAEKLEDEDRK----RAAQVAMI 76 Query: 79 TSNFGFSLLRKISMRHDG--NMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPT 136 T+ GF + + ++ G + SP + + LG+ PT +Q++ L + P Sbjct: 77 TNFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDV----PV 132 Query: 137 KPGLLPSLFKGLRETLSRNLELGL--TQGSFA-------------FIHKDFDVKETFFNL 181 K G S G + + GL TQG + F F +K +F Sbjct: 133 KEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIVVGLFTAPGFRLKHSFVQ- 191 Query: 182 SKRYFDTECVPMNFRNASQ---AKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILF 238 S F P + ++ A +N +I T K+ + ++ ++ L+ Y+ F Sbjct: 192 SLALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTDSTLLFNTYVHF 251 Query: 239 KGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATM 298 +G + F + V F +D ++ VPM+ G G F D V +P AT+ Sbjct: 252 QGT-MRGFSQL-PGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLGERATL 309 Query: 299 LVVLMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIR 358 L++ + D +E + + + TW+ N R + + P+ ++ Y + +LL + + Sbjct: 310 LLIQPHCISDLDRVEALIFQNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLP 369 Query: 359 RIFSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKV-- 416 + A+L+ + T N +V VL ++E+ E + + P + V Sbjct: 370 TLLGAEANLNNIGDT--NPRVGEVLNSILLELKAGEEEQPT---TSVQQPGSPEALDVTL 424 Query: 417 DRPFHFMIYEETSGMLLFLGRVVNP 441 PF F IYE+ SG L FLGRV NP Sbjct: 425 SSPFLFAIYEQDSGTLHFLGRVNNP 449 >2WXZ-C nrPDB Length = 453 Score = 86.3 bits (212), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 109/451 (24%), Positives = 183/451 (40%), Gaps = 62/451 (13%) Query: 20 PGLAPSPQSPETPAPQNQTSR---VVQAPKEEEEDEQEASEEKASEEEKAWLMASRQQLA 76 P P P +T +T R V+ K E ED Q A+ Q+A Sbjct: 32 PTFEPVPIQAKTSPVDEKTLRDKLVLATEKLEAEDRQRAA-----------------QVA 74 Query: 77 KETSNFGFSLLRKISMRHD--GNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALK 134 + GF + + +S V SP + + LG+ PT +Q++ L + Sbjct: 75 MIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGV---- 130 Query: 135 PTKPGLLPSLFKGLRETLSRNLELGL--TQGSFA-------------FIHKDFDVKETFF 179 P K G S G + + GL TQG + F +K+ F Sbjct: 131 PVKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFV 190 Query: 180 NLSKRYFDTECVPMNFRNASQ---AKRLMNHYINKETRGKIPKLFDEINPETKLILVDYI 236 S F P + ++ A + +N ++ T K+ + ++ ++ L Y+ Sbjct: 191 E-SLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFNTYV 249 Query: 237 LFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNA 296 F+GK + F + T + F +D ++ VPM+ G G F D V ++P + Sbjct: 250 HFQGK-MRGFSQL-TGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLGESV 307 Query: 297 TMLVVLMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMG 356 T+L++ + D +E + TW++N R + + P+ ++ Y + +LL Q Sbjct: 308 TLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAK 367 Query: 357 IRRIFSPFADLSELSATGRNLQVSRVLQRTVIEV----DERGTEAVAGILSEITAYSMPP 412 + + A+L ++ T N +V VL ++E+ +E+ TE+ S P Sbjct: 368 LSTLLGAEANLGKMGDT--NPRVGEVLNSILLELQAGEEEQPTESAQQPGS-------PE 418 Query: 413 VIKV--DRPFHFMIYEETSGMLLFLGRVVNP 441 V+ V PF F IYE SG L FLGRV NP Sbjct: 419 VLDVTLSSPFLFAIYERDSGALHFLGRVDNP 449 >1MTP-A nrPDB Length = 323 Score = 79.3 bits (194), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 76/316 (24%), Positives = 142/316 (44%), Gaps = 24/316 (7%) Query: 82 FGFSLLRKIS-MRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGL 140 F L R+++ DG +++SP+ ++ A+ L GA T T++ L L Sbjct: 13 FALHLHRRLAEAVPDGEVIWSPYSVACALGVLAAGARATTRTELTTLLGTDPAP-----L 67 Query: 141 LPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFR-NAS 199 L +L + + ++ L + ++ D V+ +F D++ +FR N Sbjct: 68 LAALDRAVTDSPD------LASRTVLWVSADVPVRSSFRATMHDRPDSDVRTADFRTNPE 121 Query: 200 QAKRLMNHYINKETRGKIPKLFDE--INPETKLILVDYILFKGKWLTPFDPVFTEVDTFH 257 + +N I TRG I +L + + P+ + IL + + K +W TPF+ T TF Sbjct: 122 GVRATVNADIADATRGMIRELLPQGAVTPDLRAILTNALWAKARWTTPFEAHLTREGTFR 181 Query: 258 LDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLT 317 + +VP M+ + +R L + + + VL+ + A+ T Sbjct: 182 TPRGPK-RVPFMHRTKTMPYATARGWRMVTL---HAHDELAVDVLLPPGTNAAAVP---T 234 Query: 318 TDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNL 377 L+ R + ++E+ P+F+L Q +++ E+L + G+R +F+ ADLS +S L Sbjct: 235 APLLTALHRRSASTSVELALPRFELTQPHQLVEVLAEAGVRTLFTASADLSGISTV--PL 292 Query: 378 QVSRVLQRTVIEVDER 393 V V+ + + VDER Sbjct: 293 YVDTVIHQARLRVDER 308 >5M3Y-A nrPDB Length = 458 Score = 77.0 bits (188), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 63/254 (24%), Positives = 117/254 (46%), Gaps = 16/254 (6%) Query: 193 MNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTE 252 ++F A ++ ++ T K + ++ L Y+ F+GK + F + E Sbjct: 206 LDFTELDVAAEKIDRFMQAVTGWKTGSSLMGASVDSTLAFNTYVHFQGK-MKGFS-LLAE 263 Query: 253 VDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLAL 312 F +D+ ++ VPM+ G G F D + V ++P+ +A++L++ D + Sbjct: 264 PQEFWVDQSTSVSVPMLSGMGTFQHWSDIQDQFSVTQVPFTESASLLLIQPHYASDLDKV 323 Query: 313 EDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSA 372 E W++ + R + + P+ L Y++ +LL Q + I +L +LS Sbjct: 324 EGLTFQQNSLNWMKKLSPRTIHLTMPQLVLQGSYDLQDLLAQAELPAILHTELNLQKLS- 382 Query: 373 TGRNLQVSRVLQRTV--IEVDERG-TEAVAGILSEITAYSMPPVIKV--DRPFHFMIYEE 427 ++V VL +E DER TE+ + + P V++V +RPF F +Y++ Sbjct: 383 -NDRIRVGEVLNSIFFELEADEREPTESTQQL-------NKPEVLEVTLNRPFLFAVYDQ 434 Query: 428 TSGMLLFLGRVVNP 441 ++ L FLGRV NP Sbjct: 435 SATALHFLGRVANP 448 >5C98-A nrPDB Length = 382 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 72/353 (20%), Positives = 136/353 (38%), Gaps = 33/353 (9%) Query: 97 NMVFSPFGMSLAMTGL--MLGATGPTETQIKRGL--HLQALKPTKPGLLPSLFKGLRETL 152 N SP+ + LA++ + GA + Q+ GL + A + L L G Sbjct: 38 NCAVSPYHVRLALSMFYPLAGAAVQEDFQVAFGLPEDVHAAIEQQQRLAQQLHDGQH--- 94 Query: 153 SRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINKE 212 L SF + + + F L R F T P++ + + +N + + Sbjct: 95 -------LKALSFVLVEETLRLDSEFERLFHRTFQTTVEPVDLTDDIPSALAVNSFYQR- 146 Query: 213 TRGKIPKLFDE-----INPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVP 267 +I E + P KL+L + F+P T ++ F T +V Sbjct: 147 ANTEIEDFIGEGDVFSLPPCHKLMLFSGVSVLTPLAIRFNPADTALELFQFINAPTQRVS 206 Query: 268 MMYGAGKFASTFDKNFRCHVLKLPYQGNA--TMLVVLMEKMGDHLALEDYLTTDLVETWL 325 M+ RC V+ +P+ + +MLV+L + + + +T + Sbjct: 207 TMHTTAFVRRCLHNELRCKVVDMPFDAASGLSMLVLLPYDGTELRQIVNSITPAHLAQID 266 Query: 326 RNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSRVLQR 385 +++ ++ PKF + +K + + L ++G +F DL +GR +++ +Q Sbjct: 267 ERLQSCWTDLKLPKFFVREKTDPKQTLGKLGYGGVFE-IDDLHVFHDSGRT-RLNGFIQH 324 Query: 386 TVIEVDERGT--EAVAGILSEITAYSMPPVIKVDRPFHFMIYEETSGMLLFLG 436 + V E G+ A SE ++ +RPF F+I G +L +G Sbjct: 325 CYLAVSESGSGIPAPPDTPSEFEFHA-------NRPFMFLIRRTMDGNVLQVG 370 >4N9N-A nrPDB Length = 438 Score = 29.6 bits (65), Expect = 2.5, Method: Compositional matrix adjust. Identities = 23/103 (22%), Positives = 45/103 (43%), Gaps = 10/103 (9%) Query: 336 FFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSRVLQRTVIEVDERGT 395 + P+ D + MH LL + L + ++ R L R+L+ V+E+ E T Sbjct: 45 YIPELAFDYPFLMHALL-AFSATHLSRTETGLEQYVSSHR-LDALRLLREAVLEISENNT 102 Query: 396 EAVAG-----ILSEITAYSMPPV---IKVDRPFHFMIYEETSG 430 +A+ I+ + S+ + +++D IY++T G Sbjct: 103 DALVASALILIMDSLANASVDNIFEMLRIDEGLRLKIYKDTEG 145 >2YCH-A nrPDB Length = 377 Score = 28.9 bits (63), Expect = 4.5, Method: Compositional matrix adjust. Identities = 35/122 (28%), Positives = 46/122 (37%), Gaps = 23/122 (18%) Query: 309 HLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRI-------- 360 L LE V T L N+ + PK L EM E +R R I Sbjct: 67 ELLLEARTRKRYVVTALSNLAVILRPIQVPKMPLK---EMEEAVRWEAERYIPFPIDEVV 123 Query: 361 --FSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDR 418 F+P LSE+ G +QV R EAVAG+L + + PV+ + Sbjct: 124 LDFAPLTPLSEVQ-EGEQVQVMVAAARQ---------EAVAGVLEALRGAGLVPVVLDVK 173 Query: 419 PF 420 PF Sbjct: 174 PF 175 >3G2F-A nrPDB Length = 336 Score = 28.5 bits (62), Expect = 6.4, Method: Compositional matrix adjust. Identities = 10/24 (41%), Positives = 17/24 (70%) Query: 88 RKISMRHDGNMVFSPFGMSLAMTG 111 R + +++DG V S FG+S+ +TG Sbjct: 149 RNVLVKNDGTCVISDFGLSMRLTG 172 >6D4C-A nrPDB Length = 364 Score = 28.5 bits (62), Expect = 6.8, Method: Compositional matrix adjust. Identities = 27/128 (21%), Positives = 55/128 (42%), Gaps = 15/128 (11%) Query: 266 VPMMYGAGKFASTFDKNFRCHVLKLPY----QGNATMLVVLMEKMGDHLALEDYL-TTDL 320 V ++Y AGK A+ +K + C KL + L+ +K G + L+ ++ D+ Sbjct: 4 VLVLYDAGKHAADEEKLYGCTENKLGIANWLKDQGHELITTSDKEGGNSVLDQHIPDADI 63 Query: 321 VETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVS 380 + T F P + ++ + + L+ + + + S DL ++ TG+ + V Sbjct: 64 IIT----------TPFHPAYITKERIDKAKKLKLVVVAGVGSDHIDLDYINQTGKKISVL 113 Query: 381 RVLQRTVI 388 V V+ Sbjct: 114 EVTGSNVV 121 >4N5A-A nrPDB Length = 557 Score = 27.7 bits (60), Expect = 10.0, Method: Compositional matrix adjust. Identities = 20/85 (23%), Positives = 42/85 (49%), Gaps = 7/85 (8%) Query: 151 TLSRNLELGLTQGSFAFIHKDFDVKETFFNL-SKRYFDTE-----CVPMNFRNASQAKRL 204 ++ +NL+ L G F+ + + FF + ++R + + C+ ++ N+ + Sbjct: 122 SICQNLDDVLCNGDMEFVQLYQNFVDLFFKIVTERIHNDDMLLKCCIDISNTNSVSSNPQ 181 Query: 205 MNHYINKETRGKIPKLFDEINPETK 229 +NH+++K I K F E NP+ K Sbjct: 182 LNHFVSKSVAYTISK-FQERNPKFK 205 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6EE5-A nrPDB 532 e-151 4AJU-A nrPDB 483 e-137 3NE4-A nrPDB 453 e-128 4AJT-A nrPDB 451 e-127 2VDY-A nrPDB 433 e-122 6HGE-B nrPDB 432 e-121 2OL2-A nrPDB 420 e-118 5HGC-A nrPDB 420 e-118 4EB1-I nrPDB 413 e-116 1ATT-A nrPDB 412 e-115 1BY7-A nrPDB 406 e-113 4Y40-A nrPDB 402 e-112 1YXA-A nrPDB 399 e-111 1JMJ-A nrPDB 392 e-109 4ZK0-A nrPDB 390 e-109 3DY0-A nrPDB 388 e-108 4GA7-A nrPDB 387 e-108 6F02-A nrPDB 386 e-107 3NDA-A nrPDB 385 e-107 1C5G-A nrPDB 382 e-106 1QMB-A nrPDB 378 e-105 1UHG-A nrPDB 377 e-105 2XN5-A nrPDB 376 e-104 5INW-A nrPDB 375 e-104 2V95-A nrPDB 373 e-104 3LW2-A nrPDB 372 e-103 4P0F-A nrPDB 370 e-103 4KDS-A nrPDB 367 e-102 4DY0-A nrPDB 366 e-101 2H4Q-A nrPDB 363 e-101 1HLE-A nrPDB 357 4e-99 2H4P-A nrPDB 356 9e-99 4DTE-A nrPDB 355 3e-98 6F4U-A nrPDB 352 2e-97 5NCS-A nrPDB 350 1e-96 3ZHA-A nrPDB 341 4e-94 3F02-A nrPDB 340 8e-94 1IMV-A nrPDB 336 1e-92 3OZQ-A nrPDB 334 6e-92 2R9Y-A nrPDB 324 5e-89 1XQJ-A nrPDB 321 4e-88 1K9O-I nrPDB 318 4e-87 6CJ7-A nrPDB 317 5e-87 1SEK-A nrPDB 314 6e-86 3PZF-A nrPDB 312 2e-85 5NCU-A nrPDB 311 3e-85 2WXX-A nrPDB 304 4e-83 2WXZ-C nrPDB 300 9e-82 3STO-A nrPDB 299 2e-81 3LE2-A nrPDB 298 3e-81 2PEF-A nrPDB 297 8e-81 1C8O-A nrPDB 286 2e-77 2OAY-A nrPDB 278 2e-75 1JJO-C nrPDB 274 7e-74 1SNG-A nrPDB 266 2e-71 5M3Y-A nrPDB 263 8e-71 5C98-A nrPDB 249 1e-66 6BJ5-B nrPDB 246 2e-65 1M93-B nrPDB 244 5e-65 1MTP-A nrPDB 240 8e-64 Sequences not found previously or not previously below threshold: 4R9I-A nrPDB 94 2e-19 1O4S-A nrPDB 34 0.15 4PSX-A nrPDB 31 0.79 5W76-A nrPDB 31 0.81 5U6P-A nrPDB 31 1.1 6EEM-B nrPDB 31 1.1 4P2L-A nrPDB 31 1.2 4AXG-A nrPDB 30 1.5 6DS5-A nrPDB 30 1.8 3H1Q-A nrPDB 30 2.0 5I9J-A nrPDB 29 3.7 3T59-A nrPDB 29 4.3 5CA8-A nrPDB 29 4.5 1W1W-A nrPDB 28 6.7 >6EE5-A nrPDB Length = 379 Score = 532 bits (1371), Expect = e-151, Method: Composition-based stats. Identities = 147/376 (39%), Positives = 224/376 (59%), Gaps = 10/376 (2%) Query: 67 WLMASRQQLAKETSNFGFSLLRKISMR-HDGNMVFSPFGMSLAMTGLMLGATGPTETQIK 125 AS +LA+ ++F FSL R+++ D N+ FSP +S A+ L LGA G T TQI Sbjct: 13 QGAASSHKLAEANTDFAFSLYRELAKSSPDKNIFFSPVSISSALAMLSLGAKGDTHTQIL 72 Query: 126 RGLHLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRY 185 GL + F+ L +TL+R L L + F+ K + ++F SK+ Sbjct: 73 EGLGFN-----SEADIHQGFQHLLQTLNRPKGLQLKTANGLFVDKSLKLLDSFLEDSKKL 127 Query: 186 FDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTP 245 + E ++F + +AK+ +N ++ K+T GKI L +++ +T L+LV+ I FKGKW P Sbjct: 128 YQAEAFSVDF-DPEEAKKQINDWVEKQTNGKIKDLLKDLDSDTVLVLVNAIYFKGKWKKP 186 Query: 246 FDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEK 305 FDP T+ + FH+D+ T+KVPMM GKF D C VL+LPY+GNA+ML++L ++ Sbjct: 187 FDPENTKEEDFHVDEKTTVKVPMMSQKGKFYYYHDDELSCKVLELPYKGNASMLIILPDE 246 Query: 306 MGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFA 365 G LE LT + + WL+++ R++E++ PKFK++ Y++ E+L +GI +FSP A Sbjct: 247 -GGLQHLEQSLTPETLSKWLKSLTRRSVELYLPKFKIEGTYDLKEVLSNLGITDLFSPGA 305 Query: 366 DLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIY 425 DLS ++ L VS+ + + V+EV+E GTEA A E S+PP K DRPF F+I Sbjct: 306 DLSGITE--EKLYVSKAVHKAVLEVNEEGTEAAAATFLEAIPMSIPPEFKADRPFLFLIR 363 Query: 426 EETSGMLLFLGRVVNP 441 E +G +LF+G+VVNP Sbjct: 364 ENKTGSILFMGKVVNP 379 >4AJU-A nrPDB Length = 387 Score = 483 bits (1244), Expect = e-137, Method: Composition-based stats. Identities = 385/386 (99%), Positives = 385/386 (99%) Query: 23 APSPQSPETPAPQNQTSRVVQAPKEEEEDEQEASEEKASEEEKAWLMASRQQLAKETSNF 82 APSPQSPETPAPQNQTSRVVQAPKEEEEDEQEASEEKASEEEKAWLMASRQQLAKETSNF Sbjct: 2 APSPQSPETPAPQNQTSRVVQAPKEEEEDEQEASEEKASEEEKAWLMASRQQLAKETSNF 61 Query: 83 GFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLP 142 GFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLP Sbjct: 62 GFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLP 121 Query: 143 SLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAK 202 SLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAK Sbjct: 122 SLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAK 181 Query: 203 RLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYK 262 RLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYK Sbjct: 182 RLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYK 241 Query: 263 TIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLTTDLVE 322 TIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLTTDLVE Sbjct: 242 TIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLTTDLVE 301 Query: 323 TWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSRV 382 TWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSRV Sbjct: 302 TWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSRV 361 Query: 383 LQRTVIEVDERGTEAVAGILSEITAY 408 LQRTVIEVDERGTEAVAGILSEITA Sbjct: 362 LQRTVIEVDERGTEAVAGILSEITAR 387 >3NE4-A nrPDB Length = 424 Score = 453 bits (1165), Expect = e-128, Method: Composition-based stats. Identities = 129/396 (32%), Positives = 212/396 (53%), Gaps = 5/396 (1%) Query: 49 EEDEQEASEEKASEEEKAWLMASRQQLAKETSNFGFSLLRKIS-MRHDGNMVFSPFGMSL 107 ED Q + +K + ++ + F FSL R+++ + N+ FSP ++ Sbjct: 30 AEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIAT 89 Query: 108 AMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSR-NLELGLTQGSFA 166 A L LG T +I GL+ L + F+ L TL++ + +L LT G+ Sbjct: 90 AFAMLSLGTKADTHDEILEGLNFN-LTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGL 148 Query: 167 FIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINP 226 F+ + + + F K+ + +E +NF + +AK+ +N Y+ K T+GKI L E++ Sbjct: 149 FLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDR 208 Query: 227 ETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCH 286 +T LV+YI FKGKW PF+ TE + FH+D+ T+KVPMM G F K Sbjct: 209 DTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSW 268 Query: 287 VLKLPYQGNATMLVVLMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKY 346 VL + Y GNAT + L ++ G LE+ LT D++ +L N R+ + PK + Y Sbjct: 269 VLLMKYLGNATAIFFLPDE-GKLQHLENELTHDIITKFLENEDRRSASLHLPKLSITGTY 327 Query: 347 EMHELLRQMGIRRIFSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEIT 406 ++ +L Q+GI ++FS ADLS ++ L++S+ + + V+ +DE+GTEA + E Sbjct: 328 DLKSVLGQLGITKVFSNGADLSGVTEEA-PLKLSKAVHKAVLTIDEKGTEAAGAMFLEAI 386 Query: 407 AYSMPPVIKVDRPFHFMIYEETSGMLLFLGRVVNPT 442 S+PP +K ++PF F++ E+ + LF+G+VVNPT Sbjct: 387 PMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNPT 422 >4AJT-A nrPDB Length = 427 Score = 451 bits (1161), Expect = e-127, Method: Composition-based stats. Identities = 292/378 (77%), Positives = 332/378 (87%), Gaps = 1/378 (0%) Query: 67 WLMASRQQLAKETSNFGFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKR 126 WL AS QQL+ ETS+FGF+LLRKISMRHDGN++FSPFG+S+AM LMLG G T+ QI+ Sbjct: 51 WLRAS-QQLSNETSSFGFNLLRKISMRHDGNVIFSPFGLSVAMVNLMLGTKGETKVQIEN 109 Query: 127 GLHLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYF 186 GL+LQAL P +LP+LFK ++ET S N +LGL+QGSFAFIHKDFD+KET+FNLSK+YF Sbjct: 110 GLNLQALSQAGPLILPALFKKVKETFSSNRDLGLSQGSFAFIHKDFDIKETYFNLSKKYF 169 Query: 187 DTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPF 246 D E V +NF+N+SQA+ L+NH I KET GKIPKLFDEINPETKLILVDY+LFKGKWLTPF Sbjct: 170 DIEYVSINFQNSSQARGLINHCIVKETEGKIPKLFDEINPETKLILVDYVLFKGKWLTPF 229 Query: 247 DPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKM 306 DP FTE DTFHLDKY+ IKVPMMY G F STFDK FRCH+LKLPYQGNATMLVVLMEK Sbjct: 230 DPSFTEADTFHLDKYRAIKVPMMYREGNFTSTFDKKFRCHILKLPYQGNATMLVVLMEKT 289 Query: 307 GDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFAD 366 GD+LALEDYLT DLVETWL+NMKTR MEVFFPKFKL+Q+YEMHELL+QMGIRR+FS AD Sbjct: 290 GDYLALEDYLTVDLVETWLQNMKTRKMEVFFPKFKLNQRYEMHELLKQMGIRRLFSTSAD 349 Query: 367 LSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYE 426 LSELSA RNLQVSRVLQ++V+EVDERGTEAV+G LSEI AYSMPP IKV+RPFHF+IYE Sbjct: 350 LSELSAMARNLQVSRVLQQSVLEVDERGTEAVSGTLSEIIAYSMPPAIKVNRPFHFIIYE 409 Query: 427 ETSGMLLFLGRVVNPTLL 444 E S MLLFLGRVVNPT+L Sbjct: 410 EMSRMLLFLGRVVNPTVL 427 >2VDY-A nrPDB Length = 373 Score = 433 bits (1114), Expect = e-122, Method: Composition-based stats. Identities = 109/373 (29%), Positives = 201/373 (53%), Gaps = 5/373 (1%) Query: 72 RQQLAKETSNFGFSLLRK-ISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHL 130 + LA +F FSL + +++ N+ SP +S+A+ L LG G T Q+ +GL Sbjct: 4 HRGLASANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGF 63 Query: 131 QALKPTKPGLLPSLFKGLRETLSR-NLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTE 189 L + F+ L + ++ + L +T G+ F+ ++ E+F K Y+++E Sbjct: 64 N-LTERSETEIHQGFQHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESE 122 Query: 190 CVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPV 249 + MNF++ + A R +N Y+ +T+GKI LF ++ L+LV+YI FKG W PFD Sbjct: 123 VLAMNFQDWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLA 182 Query: 250 FTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDH 309 T + F++D+ +KVPMM + + D C ++++ Y GN T+ +L +K G Sbjct: 183 STREENFYVDETTVVKVPMMLQSSTISYLHDSELPCQLVQMNYVGNGTVFFILPDK-GKM 241 Query: 310 LALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSE 369 + L+ D + W + + ++++ PK + Y++ ++L +MGI +F+ A+ S Sbjct: 242 NTVIAALSRDTINRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTTQANFSR 301 Query: 370 LSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYEETS 429 ++ + L+ S+V+ + V++++E GTEA + E S P +++ ++PF MI++ + Sbjct: 302 ITQDAQ-LKSSKVVHKAVLQLNEEGTEAAGAMFLEAIPRSKPIILRFNQPFIIMIFDHFT 360 Query: 430 GMLLFLGRVVNPT 442 LFL RV+NP Sbjct: 361 WSSLFLARVMNPV 373 >6HGE-B nrPDB Length = 409 Score = 432 bits (1110), Expect = e-121, Method: Composition-based stats. Identities = 127/393 (32%), Positives = 215/393 (54%), Gaps = 11/393 (2%) Query: 57 EEKASEEEKAWLMASRQQLAKETSNFGFSLLRKIS-MRHDGNMVFSPFGMSLAMTGLMLG 115 EE ++E + + LA +F FSL +++ D N++FSP +S A+ L LG Sbjct: 17 EENLTQENQDRGTHVDRGLASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLG 76 Query: 116 ATGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSRNL-ELGLTQGSFAFIHKDFDV 174 A T T+I +GL L T + F+ L TL+++ EL L+ G+ F+ + + Sbjct: 77 AHNTTLTEILKGLKFN-LTETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSL 135 Query: 175 KETFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVD 234 + F +KR + +E +F++++ AK+L+N Y+ TRGKI L +++ +T ++LV+ Sbjct: 136 LDRFTEDAKRLYGSEAFATDFQDSAAAKKLINDYVKNGTRGKITDLIKDLDSQTMMVLVN 195 Query: 235 YILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAG-KFASTFDKNFRCHVLKLPYQ 293 YI FK KW PFDP T F+L K K + VPMM D+ C V++L Y Sbjct: 196 YIFFKAKWEMPFDPQDTHQSRFYLSKKKWVMVPMMSLHHLTIPYFRDEELSCTVVQLNYT 255 Query: 294 GNATMLVVLMEKMGDHLALEDYLTTDLVETWLRNMKTRNM-EVFFPKFKLDQKYEMHELL 352 GNA+ L +L ++ +E L+ + + W +++ R + E++ PKF + + Y ++++L Sbjct: 256 GNASALFILPDQ-DKMEEVEAMLSRETLNRWGDSLEFREIGELYLPKFSISRDYNLNDIL 314 Query: 353 RQMGIRRIFSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYS--- 409 Q+GI F+ ADLS ++ RNL VS+V+ + V++V E GTEA A +IT S Sbjct: 315 LQLGIEEAFTSKADLSGITG-ARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLLSALV 373 Query: 410 -MPPVIKVDRPFHFMIYEETSGMLLFLGRVVNP 441 +++ +RPF +I + + + F+ +V NP Sbjct: 374 ETRTIVRFNRPFLMIIVDHFTWSIFFMSKVTNP 406 >2OL2-A nrPDB Length = 395 Score = 420 bits (1080), Expect = e-118, Method: Composition-based stats. Identities = 119/365 (32%), Positives = 194/365 (53%), Gaps = 9/365 (2%) Query: 81 NFGFSLLRKI-SMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPG 139 +F F L R + S N+ FSP +S+++ L LGA T+ QI GL L K ++ Sbjct: 36 DFTFDLYRALASAAPSQNIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKE 95 Query: 140 LLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNAS 199 L + L+E L+ G+ F D+++TF + K + + P NFR+++ Sbjct: 96 LHRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSA 155 Query: 200 QAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLD 259 A + +N Y+ K+T+GKI L ++ +I+V+YI FK KW T F+ T+ F++ Sbjct: 156 GAMKQINDYVAKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVT 215 Query: 260 KYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLTTD 319 ++VPMM ++ D+N C V+ +PYQGNAT L +L + G +E+ L+ Sbjct: 216 SETVVRVPMMSREDQYHYLLDRNLSCRVVGVPYQGNATALFILPSE-GKMQQVENGLSEK 274 Query: 320 LVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQV 379 + WL+ K R +E++ PKF ++ Y++ ++L +GI +F+ ADLS +S N+QV Sbjct: 275 TLRKWLKMFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGIS-NHSNIQV 333 Query: 380 SRVLQRTVIEVDERGTEAVAGILSEITAYSM---PPVIKVDRPFHFMIYEETSGMLLFLG 436 S ++ + V+EVDE GT A A + T S + +RPF I + +LFLG Sbjct: 334 SEMVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVDN---NILFLG 390 Query: 437 RVVNP 441 +V P Sbjct: 391 KVNRP 395 >5HGC-A nrPDB Length = 380 Score = 420 bits (1080), Expect = e-118, Method: Composition-based stats. Identities = 118/371 (31%), Positives = 198/371 (53%), Gaps = 3/371 (0%) Query: 74 QLAKETSNFGFSLLRKISMR-HDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQA 132 +L ++F F R+++ + N+ +SP +S A L LGA T++QI GL Sbjct: 10 KLVPNNADFAFQFFREVTQEAPNKNIFYSPVSISTAFAMLALGARSATQSQILEGLAFNL 69 Query: 133 LKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVP 192 + + + + + L + F+ + F + +K + E Sbjct: 70 TEIQEKEIHEGFHNLIHMLNHPEGGVQLNMMNAIFVTAALALLRKFLDDAKALYQLEAFT 129 Query: 193 MNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTE 252 +F ++A++ +N YI ++T GKI L +++P+T ++L ++ FKG W PF+ TE Sbjct: 130 TDFNKPTEAEKQINDYIERKTHGKITNLVKDMDPQTVMLLASFVYFKGSWEKPFEAEHTE 189 Query: 253 VDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLAL 312 F +D T+KVPMMY G+F FD+ C V++L Y G+AT +VL K G L Sbjct: 190 EREFFVDAETTVKVPMMYQMGRFDFYFDEELSCTVVRLHYNGSATAFLVLPAK-GKMKQL 248 Query: 313 EDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSA 372 E L + ++ W ++ R M ++FPKF + YE+ LR+MGI +F+ ADLS ++ Sbjct: 249 EQTLDKETIQKWSDHLFQRFMNLYFPKFSISGSYEISNTLRKMGIVDVFTNQADLSGITG 308 Query: 373 TGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYEETSGML 432 + +L+VS+V+ + ++VDE+GTEA A EI S PP I+ PF +I++ + Sbjct: 309 S-PDLKVSKVVHKASLDVDEKGTEAAAATAVEIMPISFPPTIEFSHPFLMLIFDRDTNST 367 Query: 433 LFLGRVVNPTL 443 LF+G++VNPT+ Sbjct: 368 LFIGKIVNPTI 378 >4EB1-I nrPDB Length = 440 Score = 413 bits (1061), Expect = e-116, Method: Composition-based stats. Identities = 113/420 (26%), Positives = 191/420 (45%), Gaps = 26/420 (6%) Query: 45 PKEEEEDEQEASEEKASEEEKAWLMASRQQLAKETSNFGFSLLRKI--SMRHDGNMVFSP 102 E++ E E SE+K E +L+K S F + + + S + N+ SP Sbjct: 25 SPEKKATEDEGSEQKIPEATNR----RVWELSKANSRFATTFYQHLADSKNDNDNIFLSP 80 Query: 103 FGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSR--NLELGL 160 +S A LGA T Q+ + + F L L R N L Sbjct: 81 LSISTAFAMTKLGACNDTLQQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKASKL 140 Query: 161 TQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFR-NASQAKRLMNHYINKETRGKIPK 219 + F K ET+ ++S+ + + P++F+ NA Q++ +N +++ +T G+I Sbjct: 141 VSANRLFGDKSLTFNETYQDISELVYGAKLQPLDFKENAEQSRAAINKWVSNKTEGRITD 200 Query: 220 LFDE----------INPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMM 269 + T L+LV+ I FKG W + F P T + F+ ++ MM Sbjct: 201 VIPSEAINVLVLVNTRTSTVLVLVNTIYFKGLWKSKFSPENTRKELFYKADGESCSASMM 260 Query: 270 YGAGKFASTFDKNFRCHVLKLPYQGNA-TMLVVLMEKMGDHLALEDYLTTDLVETWLRNM 328 Y GKF VL+LP++G+ TM+++L + +E LT ++++ WL + Sbjct: 261 YQEGKFRYRRVAE-GTQVLELPFKGDDITMVLILPKPEKSLAKVEKELTPEVLQEWLDEL 319 Query: 329 KTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPF-ADLSELSATGR-NLQVSRVLQRT 386 + + V P+F+++ + + E L+ MG+ +FSP + L + A GR +L VS + Sbjct: 320 EEMMLVVHMPRFRIEDGFSLKEQLQDMGLVDLFSPEKSKLPGIVAEGRDDLYVSDAFHKA 379 Query: 387 VIEVDERGTEAVAGILSEITAYSMPP---VIKVDRPFHFMIYEETSGMLLFLGRVVNPTL 443 +EV+E G+EA A I S+ P K +RPF I E ++F+GRV NP + Sbjct: 380 FLEVNEEGSEAAASTAVVIAGRSLNPNRVTFKANRPFLVFIREVPLNTIIFMGRVANPCV 439 >1ATT-A nrPDB Length = 429 Score = 412 bits (1060), Expect = e-115, Method: Composition-based stats. Identities = 117/409 (28%), Positives = 200/409 (48%), Gaps = 15/409 (3%) Query: 49 EEDEQEASEEKASEEEKAWLMASR-QQLAKETSNFGFSLLRKI--SMRHDGNMVFSPFGM 105 E++A+E + SE++ R +L+K S+F + + + S ++ N+ SP + Sbjct: 21 RSSEKKATEGQGSEQKIPGATNRRVWELSKANSHFATAFYQHLADSKNNNDNIFLSPLSI 80 Query: 106 SLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSR--NLELGLTQG 163 S A LGA T TQ+ + + F L L R N L Sbjct: 81 STAFAMTKLGACNNTLTQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKSSELVSA 140 Query: 164 SFAFIHKDFDVKETFFNLSKRYFDTECVPMNFR-NASQAKRLMNHYINKETRGKIPKLFD 222 + F K ET+ ++S+ + + P++F+ NA Q++ +N +I+ +T G+I + Sbjct: 141 NRLFGDKSITFNETYQDISEVVYGAKLQPLDFKGNAEQSRLTINQWISNKTEGRITDVIP 200 Query: 223 E--INPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFD 280 IN T L+LV+ I FKG W + F P T + F+ ++ V MMY KF Sbjct: 201 PQAINEFTVLVLVNTIYFKGLWKSKFSPENTRKELFYKADGESCSVLMMYQESKFRYRRV 260 Query: 281 KNFRCHVLKLPYQGNATMLVVLMEKMGDHLA-LEDYLTTDLVETWLRNMKTRNMEVFFPK 339 VL+LP++G+ +V+++ K+ LA +E LT D+++ WL + + V P+ Sbjct: 261 AE-STQVLELPFKGDDITMVLILPKLEKTLAKVEQELTPDMLQEWLDELTETLLVVHMPR 319 Query: 340 FKLDQKYEMHELLRQMGIRRIFSPF-ADLSELSATGR-NLQVSRVLQRTVIEVDERGTEA 397 F+++ + + E L+ MG+ +FSP + L + A GR +L VS + +EV+E G+EA Sbjct: 320 FRIEDSFSVKEQLQDMGLEDLFSPEKSRLPGIVAEGRSDLYVSDAFHKAFLEVNEEGSEA 379 Query: 398 VAGILSEITAYSMPP---VIKVDRPFHFMIYEETSGMLLFLGRVVNPTL 443 A + I S+ K +RPF +I E ++F+GRV NP + Sbjct: 380 AASTVISIAGRSLNSDRVTFKANRPFLVLIREVALNTIIFMGRVANPCV 428 >1BY7-A nrPDB Length = 382 Score = 406 bits (1043), Expect = e-113, Method: Composition-based stats. Identities = 105/384 (27%), Positives = 195/384 (50%), Gaps = 16/384 (4%) Query: 72 RQQLAKETSNFGFSLLRKISM-RHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHL 130 + L + F +L + ++ N+ SP+ +S M + +G+ G TE Q+ + L Sbjct: 1 MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60 Query: 131 QALKPTKPGLLPSLFKGLRETLSRNLE-LGLTQGSFAFIHKDFDVKETFFNLSKRYFDTE 189 + + S F+ L ++ + L + F K +E + L ++Y+ +E Sbjct: 61 NEVG-AAADKIHSSFRSLSSAINASTGNYLLESVNKLFGEKSASFREEYIRLCQKYYSSE 119 Query: 190 CVPMNF-RNASQAKRLMNHYINKETRGKIPKLFDE--INPETKLILVDYILFKGKWLTPF 246 ++F A +A++ +N ++ +T+GKIP L E ++ +T+++LV+ + FKGKW TPF Sbjct: 120 PQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPF 179 Query: 247 DPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKM 306 + + F ++ + V MMY K + ++ + +L+LPY G+ +M ++L +++ Sbjct: 180 EKKLNGLYPFRVNSAQRTPVQMMYLREKLNIGYIEDLKAQILELPYAGDVSMFLLLPDEI 239 Query: 307 GDHLA----LEDYLTTDLVETWL--RNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRI 360 D LE +T D + W M +EV+ P+FKL++ YE+ +LR MG+ Sbjct: 240 ADVSTGLELLESEITYDKLNKWTSKDKMAEDEVEVYIPQFKLEEHYELRSILRSMGMEDA 299 Query: 361 FSPF-ADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMP--PVIKVD 417 F+ A+ S +S +L +S V + +++V+E GTEA AG +T + P D Sbjct: 300 FNKGRANFSGMSERN-DLFLSEVFHQAMVDVNEEGTEAAAGTGGVMTGRTGHGGPQFVAD 358 Query: 418 RPFHFMIYEETSGMLLFLGRVVNP 441 PF F+I + + +LF GR +P Sbjct: 359 HPFLFLIMHKITNCILFFGRFSSP 382 >4Y40-A nrPDB Length = 414 Score = 402 bits (1032), Expect = e-112, Method: Composition-based stats. Identities = 116/385 (30%), Positives = 209/385 (54%), Gaps = 6/385 (1%) Query: 59 KASEEEKAWLM-ASRQQLAKETSNFGFSLLRKISMRHDG-NMVFSPFGMSLAMTGLMLGA 116 KA E + W + ++LA++ + GF LL+K++ + G N+ SP +S A + L LGA Sbjct: 31 KALSEVQGWKQRMAAKELARQNMDLGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLGA 90 Query: 117 TGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKE 176 T +IK+G + + + L + E + +L L+ G+ FI + + Sbjct: 91 QDSTLDEIKQGFNFRKMPEK--DLHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQPQR 148 Query: 177 TFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYI 236 F +K ++ E + NF+N A++ +N +I+++T GKI L + I+P T ++L +YI Sbjct: 149 KFLEDAKNFYSAETILTNFQNLEMAQKQINDFISQKTHGKINNLIENIDPGTVMLLANYI 208 Query: 237 LFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNA 296 F+ +W FDP T+ + F L+K ++KVPMM+ +G + +D C +L++PYQ N Sbjct: 209 FFRARWKHEFDPNVTKEEDFFLEKNSSVKVPMMFRSGIYQVGYDDKLSCTILEIPYQKNI 268 Query: 297 TMLVVLMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMG 356 T + +L ++ G LE L D W + R + V P+ + +++ + L +G Sbjct: 269 TAIFILPDE-GKLKHLEKGLQVDTFSRWKTLLSRRVVCVSVPRLHMTGTFDLKKTLSYIG 327 Query: 357 IRRIFSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKV 416 + +IF DL++++ R+L+V + + +++DERGTE AG ++ P +K+ Sbjct: 328 VSKIFEEHGDLTKIAP-HRSLKVGEAVHKAELKMDERGTEGAAGTGAQTLPMETPLCVKI 386 Query: 417 DRPFHFMIYEETSGMLLFLGRVVNP 441 D+P+ +IY E +LFLG++VNP Sbjct: 387 DKPYLLLIYSEKIPSVLFLGKIVNP 411 >1YXA-A nrPDB Length = 398 Score = 399 bits (1025), Expect = e-111, Method: Composition-based stats. Identities = 118/387 (30%), Positives = 200/387 (51%), Gaps = 8/387 (2%) Query: 61 SEEEKAWLMASRQQLAKETSNFGFSLLRKIS-MRHDGNMVFSPFGMSLAMTGLMLGATGP 119 E+ LA ++F FSL +++ D N+VFSP +S A+ + LGA G Sbjct: 13 QEDHDNGTQLDSLTLASINTDFAFSLYKELVLKNPDTNIVFSPLSISAALALVSLGAKGN 72 Query: 120 TETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFF 179 T +I GL + ++ + L+ ++ ++ GS FI K + F Sbjct: 73 TLEEILEGLKFNLTETSEADIHQGFGHLLQRLNQPKDQVQISTGSALFIEKRQQILTEFQ 132 Query: 180 NLSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFK 239 +K + E +F+ QAK+L+N Y+ K+T+G I +L +++ T ++LV+YI FK Sbjct: 133 EKAKTLYQAEAFTADFQQPRQAKKLINDYVRKQTQGMIKELVSDLDKRTLMVLVNYIYFK 192 Query: 240 GKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAG-KFASTFDKNFRCHVLKLPYQGNATM 298 KW PFDP+ T F+ K + + VPMM D+ C V++L Y GNA+ Sbjct: 193 AKWKVPFDPLDTFKSEFYCGKRRPVIVPMMSMEDLTTPYFRDEELSCTVVELKYTGNASA 252 Query: 299 LVVLMEKMGDHLALEDYLTTDLVETWLRNMKTRNM-EVFFPKFKLDQKYEMHELLRQMGI 357 L +L ++ G +E L + + W ++K R + E+ PKF + Y + ++L ++GI Sbjct: 253 LFILPDQ-GRMQQVEASLQPETLRKWKNSLKPRMIDELHLPKFSISTDYSLEDVLSKLGI 311 Query: 358 RRIFSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSM---PPVI 414 R +FS ADLS ++ T ++L+VS+V+ + V++V E GTEA A + S P + Sbjct: 312 REVFSTQADLSAITGT-KDLRVSQVVHKAVLDVAETGTEAAAATGVKFVPMSAKLYPLTV 370 Query: 415 KVDRPFHFMIYEETSGMLLFLGRVVNP 441 +RPF MI++ + + F+ ++ NP Sbjct: 371 YFNRPFLIMIFDTETEIAPFIAKIANP 397 >1JMJ-A nrPDB Length = 480 Score = 392 bits (1006), Expect = e-109, Method: Composition-based stats. Identities = 118/382 (30%), Positives = 187/382 (48%), Gaps = 10/382 (2%) Query: 68 LMASRQQLAKETSNFGFSLLRKI--SMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIK 125 + Q+L + F F+L R + + N+ +P G+S AM + LG G T Q+ Sbjct: 100 GKSRIQRLNILNAKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVH 159 Query: 126 RGLHL----QALKPTKPGLLPSLFKGLRETL-SRNLELGLTQGSFAFIHKDFDVKETFFN 180 LH A + + +LF+ L L RN L + +I K F + F Sbjct: 160 SILHFKDFVNASSKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKT 219 Query: 181 LSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKG 240 + Y+ E +F + + + N++I K T+G I + I+P T++++++ I FKG Sbjct: 220 KVREYYFAEAQIADFSDPAFISKT-NNHIMKLTKGLIKDALENIDPATQMMILNCIYFKG 278 Query: 241 KWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLV 300 W+ F T F L++ + +KV MM G F + D+ C +L+L Y G +ML+ Sbjct: 279 SWVNKFPVEMTHNHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVGGISMLI 338 Query: 301 VLMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRI 360 V+ KM LE LT +VE W ++M R EV PKFKL++ Y + E L+ MGIR + Sbjct: 339 VVPHKMSGMKTLEAQLTPRVVERWQKSMTNRTREVLLPKFKLEKNYNLVESLKLMGIRML 398 Query: 361 FSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPF 420 F +++ +S + + + + I V+E GT+A S VDRPF Sbjct: 399 FDKNGNMAGISD--QRIAIDLFKHQGTITVNEEGTQATTVTTVGFMPLSTQVRFTVDRPF 456 Query: 421 HFMIYEETSGMLLFLGRVVNPT 442 F+IYE + LLF+GRV NP+ Sbjct: 457 LFLIYEHRTSCLLFMGRVANPS 478 >4ZK0-A nrPDB Length = 390 Score = 390 bits (1001), Expect = e-109, Method: Composition-based stats. Identities = 99/391 (25%), Positives = 183/391 (46%), Gaps = 22/391 (5%) Query: 72 RQQLAKETSNFGFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQ 131 L++ + F F L ++ + N+ +SP ++ A+ ++LGA T QIK+ LH Sbjct: 1 MNSLSEANTKFMFDLFQQFRKSKENNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHFD 60 Query: 132 ALKPTKPG------------LLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFF 179 + G + K L E L + F K + + + Sbjct: 61 QVTENTTGKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYLFLQEYL 120 Query: 180 NLSKRYFDTECVPMNFRN-ASQAKRLMNHYINKETRGKIPKLFDE--INPETKLILVDYI 236 + K+++ T ++F N ++++ +N ++ +T KI L E I T L+LV+ I Sbjct: 121 DAIKKFYQTSVESVDFANAPEESRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVNAI 180 Query: 237 LFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQG-N 295 FKG+W F+ T+ + F +K + MM F ++ + VL++PY+G + Sbjct: 181 YFKGQWEKKFNKEDTKEEKFWPNKNTYKSIQMMRQYTSFHFASLEDVQAKVLEIPYKGKD 240 Query: 296 ATMLVVLMEKMGDHLALEDYLTTDLVETW--LRNMKTRNMEVFFPKFKLDQKYEMHELLR 353 +M+V+L ++ LE+ LT + + W L+NM+ +++ P+FK+++ Y++ + LR Sbjct: 241 LSMIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRETRVDLHLPRFKVEESYDLKDTLR 300 Query: 354 QMGIRRIFSPFADLSELSATGRNLQVSRVLQRTVI---EVDERGTEAVAGILSEITAYSM 410 MG+ IF+ ADLS ++ + R L +S VL + + E A A + + S Sbjct: 301 TMGMVDIFNGDADLSGMTGS-RGLVLSGVLHKAFVEVTEEGAEAAAATAVVGFGSSPTST 359 Query: 411 PPVIKVDRPFHFMIYEETSGMLLFLGRVVNP 441 + PF F I + + +LF GR +P Sbjct: 360 NEEFHCNHPFLFFIRQNKTNSILFYGRFSSP 390 >3DY0-A nrPDB Length = 336 Score = 388 bits (996), Expect = e-108, Method: Composition-based stats. Identities = 108/328 (32%), Positives = 178/328 (54%), Gaps = 3/328 (0%) Query: 81 NFGFSLLRKI-SMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPG 139 +F F L R + S N+ FSP +S+++ L LGA T+ QI GL L K ++ Sbjct: 11 DFTFDLYRALASAAPSQNIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKE 70 Query: 140 LLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNAS 199 L + L+E L+ G+ F D+++TF + K + + P NFR+++ Sbjct: 71 LHRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSA 130 Query: 200 QAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLD 259 A + +N Y+ K+T+GKI L ++ +I+V+YI FK KW T F+ T+ F++ Sbjct: 131 GAMKQINDYVAKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVT 190 Query: 260 KYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLTTD 319 ++VPMM ++ D+N C V+ +PYQGNAT L +L + G +E+ L+ Sbjct: 191 SETVVRVPMMSREDQYHYLLDRNLSCRVVGVPYQGNATALFILPSE-GKMQQVENGLSEK 249 Query: 320 LVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQV 379 + WL+ K R +E++ PKF ++ Y++ ++L +GI +F+ ADLS +S N+QV Sbjct: 250 TLRKWLKMFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGIS-NHSNIQV 308 Query: 380 SRVLQRTVIEVDERGTEAVAGILSEITA 407 S ++ + V+EVDE GT A A + T Sbjct: 309 SEMVHKAVVEVDESGTRAAAATGTIFTF 336 >4GA7-A nrPDB Length = 389 Score = 387 bits (994), Expect = e-108, Method: Composition-based stats. Identities = 113/385 (29%), Positives = 196/385 (50%), Gaps = 21/385 (5%) Query: 72 RQQLAKETSNFGFSLLRKISMRHD-GNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHL 130 +QL+ + F L +S + GN+ SPF +S AM + LG G T Q+ + H Sbjct: 11 MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF 70 Query: 131 QALKPTKPGLLPSLFKGLRETLS-RNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTE 189 ++ S F+ L ++ R L + + K ++ F +++ + + Sbjct: 71 NTVEEV-----HSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGAD 125 Query: 190 CVPMNFRN-ASQAKRLMNHYINKETRGKIPKLFDE--INPETKLILVDYILFKGKWLTPF 246 ++F++ + A++ +N ++ +T GKIP+L ++ TKL+LV+ I FKG W F Sbjct: 126 LASVDFQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKF 185 Query: 247 DPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNA-TMLVVLMEK 305 T F L+K V MMY KFA + ++ +C VL+LPYQG +M+++L + Sbjct: 186 MKEATTNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDD 245 Query: 306 MGD----HLALEDYLTTDLVETWLR--NMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRR 359 + D +E+ LT + + W + N+ + V P+FKL++ Y ++ L ++G++ Sbjct: 246 IEDESTGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQD 305 Query: 360 IF-SPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPV--IKV 416 +F S ADLS +S R++ +S+++ ++ +EV+E GTEA A T P Sbjct: 306 LFNSSKADLSGMSG-ARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMDDPEENFTA 364 Query: 417 DRPFHFMIYEETSGMLLFLGRVVNP 441 D PF F I +SG +LFLGR +P Sbjct: 365 DHPFLFFIRHNSSGSILFLGRFSSP 389 >6F02-A nrPDB Length = 389 Score = 386 bits (991), Expect = e-107, Method: Composition-based stats. Identities = 108/378 (28%), Positives = 188/378 (49%), Gaps = 11/378 (2%) Query: 74 QLAKETSNFGFSLLRKISMRHDG-NMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQA 132 ++A ++F F I+ G N+ FSP +S A L LGA + +QI GL Sbjct: 6 KIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNL 65 Query: 133 LKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVP 192 + ++ + L L GS F+ + F N + ++ + Sbjct: 66 TELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFH 125 Query: 193 MNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTE 252 NF + +L+N ++ KETRGKI L E+ + ++LV+YI FK W PF T Sbjct: 126 TNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTT 185 Query: 253 VDTFHLDKYKTIKVPMMYGAGKFA-STFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLA 311 F++D+ T++VPMM + D+ C VL++ Y+G+AT+ +L + G Sbjct: 186 PKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQ-GKMRE 244 Query: 312 LEDYLTTDLVETWLRNMKTR----NMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADL 367 +E+ LT +++ W ++ R +E+ PKF + Y + ++L ++G +FS +ADL Sbjct: 245 IEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADL 304 Query: 368 SELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPP---VIKVDRPFHFMI 424 S ++ + L+ S+ + ++VDE GTEA A I +S +++ +RPF +I Sbjct: 305 SGITKQQK-LEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVI 363 Query: 425 YEETSGMLLFLGRVVNPT 442 + ++ +LFLG+VV+PT Sbjct: 364 FSTSTQSVLFLGKVVDPT 381 >3NDA-A nrPDB Length = 377 Score = 385 bits (988), Expect = e-107, Method: Composition-based stats. Identities = 114/377 (30%), Positives = 190/377 (50%), Gaps = 8/377 (2%) Query: 69 MASRQQLAKETSNFGFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGL 128 M +L K + FG LLR + + N+ FSP+ +S AM GA G T+ ++ +GL Sbjct: 1 MQEEAKLTKANNRFGLRLLRALPSGPEKNVFFSPYSVSTAMGMAFAGARGQTQQELSQGL 60 Query: 129 HLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDT 188 + T G+L + S L + A I + + ++ + + F Sbjct: 61 GFSDVDLTDAGVLDAYTHHTERLKSTPSNSTLDVANAAAIQRTLALLNSYESALQSSFGA 120 Query: 189 ECVPMNF-RNASQAKRLMNHYINKETRGKIPKLFDE-INPETKLILVDYILFKGKWLTPF 246 E ++F A +N+++ ++T KI KLF+E ++P+T L+L++ I FKG+W T F Sbjct: 121 ELHKVDFAGEPQAAVDFVNNWVKRKTHDKIEKLFNEPLDPDTLLVLLNAIYFKGEWNTAF 180 Query: 247 DPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQG-NATMLVVLMEK 305 TE F ++V M + F + + V++LPY+G + TM ++L ++ Sbjct: 181 VKEHTEKRQFFNGGVTPVEVDTMRLEARIKYRFFDDLQVEVVELPYRGLDYTMAILLPKE 240 Query: 306 MGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFA 365 L+ LT D + +L +++ R + V PKFKL+ KY + L+ +GI++IF A Sbjct: 241 NTGVEGLKQNLTIDRFQNYLSDLRERKITVLLPKFKLETKYSLKAPLQSLGIKQIFESGA 300 Query: 366 DLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSM---PPVIKVDRPFHF 422 DLS ++ +L+VS V + V+EV+E GT A A I YS+ P V +VD PF F Sbjct: 301 DLSGINDG--SLRVSAVEHKAVVEVNEEGTVAAATTGVVIVPYSLGPEPVVFRVDHPFLF 358 Query: 423 MIYEETSGMLLFLGRVV 439 I + + F+G+V Sbjct: 359 FIRNTRTDDIFFVGQVN 375 >1C5G-A nrPDB Length = 402 Score = 382 bits (981), Expect = e-106, Method: Composition-based stats. Identities = 102/376 (27%), Positives = 182/376 (48%), Gaps = 13/376 (3%) Query: 75 LAKETSNFGFSLLRKISM-RHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQAL 133 +A S+FG + ++++ D N+VFSP+G++ + L L G T+ QI+ + + Sbjct: 31 VAHLASDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFKI- 89 Query: 134 KPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPM 193 G+ P+L +E + + ++ F+ +D + + F R F + + Sbjct: 90 --DDKGMAPALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQV 147 Query: 194 NFRNASQAKRLMNHYINKETRGKIPKLFDE--INPETKLILVDYILFKGKWLTPFDPVFT 251 +F +A+ ++N ++ T+G I L + ++ T+L+LV+ + F G+W TPF T Sbjct: 148 DFSEVERARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSST 207 Query: 252 EVDTFHLDKYKTIKVPMMYGAGKFAST---FDKNFRCHVLKLPYQGNATMLVVLMEKMGD 308 FH T+ VPMM KF T +L+LPY G+ + + + Sbjct: 208 HRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKE 267 Query: 309 --HLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSP-FA 365 AL + L+ L+ W NM + PKF L+ + ++ + L +G+ +F A Sbjct: 268 VPLSALTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQA 327 Query: 366 DLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIY 425 D + LS L V++ LQ+ IEV+E GT A + ++A P I +DRPF F++ Sbjct: 328 DFTSLSDQ-EPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPEEIIMDRPFLFVVR 386 Query: 426 EETSGMLLFLGRVVNP 441 +G +LF+G+V+ P Sbjct: 387 HNPTGTVLFMGQVMEP 402 >1QMB-A nrPDB Length = 326 Score = 378 bits (971), Expect = e-105, Method: Composition-based stats. Identities = 108/330 (32%), Positives = 178/330 (53%), Gaps = 5/330 (1%) Query: 74 QLAKETSNFGFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQAL 133 ++ + F FSL R+++ + N+ FSP ++ A L LG T +I GL+ L Sbjct: 1 KITPNLAEFAFSLYRQLAHQSSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFN-L 59 Query: 134 KPTKPGLLPSLFKGLRETLSR-NLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVP 192 + F+ L TL++ + +L LT G+ F+ + + + F K+ + +E Sbjct: 60 TEIPEAAIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFT 119 Query: 193 MNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTE 252 +NF + +AK+ +N Y+ K T+GKI L E++ +T LV+YI FKGKW PF+ TE Sbjct: 120 VNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTE 179 Query: 253 VDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLAL 312 + FH+D+ T+KVPMM G F K VL + Y GNAT + L ++ G L Sbjct: 180 EEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDE-GKLQHL 238 Query: 313 EDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSA 372 E+ LT D++ +L N R+ + PK + Y++ +L Q+GI ++FS ADLS ++ Sbjct: 239 ENELTHDIITKFLEN-DRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTE 297 Query: 373 TGRNLQVSRVLQRTVIEVDERGTEAVAGIL 402 L++S+ + + V+ +DE+GTEA + Sbjct: 298 EA-PLKLSKAVHKAVLTIDEKGTEAAGAMF 326 >1UHG-A nrPDB Length = 385 Score = 377 bits (967), Expect = e-105, Method: Composition-based stats. Identities = 97/384 (25%), Positives = 184/384 (47%), Gaps = 18/384 (4%) Query: 75 LAKETSNFGFSLLRKISMRH-DGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQAL 133 + + F F + +++ + H + N+ + P + A+ + LGA T TQI + + L Sbjct: 3 IGAASMEFCFDVFKELKVHHANENIFYCPIAIMSALAMVYLGAKDSTRTQINKVVRFDKL 62 Query: 134 KP----------TKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSK 183 T + SL L + N + S + + + + + K Sbjct: 63 PGFGDSIEAQCGTSVNVHSSLRDILNQITKPNDVYSFSLASRLYAEERYPILPEYLQCVK 122 Query: 184 RYFDTECVPMNFRNAS-QAKRLMNHYINKETRGKIPKLF--DEINPETKLILVDYILFKG 240 + P+NF+ A+ QA+ L+N ++ +T G I + ++ +T ++LV+ I+FKG Sbjct: 123 ELYRGGLEPINFQTAADQARELINSWVESQTNGIIRNVLQPSSVDSQTAMVLVNAIVFKG 182 Query: 241 KWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQ-GNATML 299 W F T+ F + + ++ V MMY G F + + +L+LP+ G +ML Sbjct: 183 LWEKAFKDEDTQAMPFRVTEQESKPVQMMYQIGLFRVASMASEKMKILELPFASGTMSML 242 Query: 300 VVLMEKMGDHLALEDYLTTDLVETWLRN--MKTRNMEVFFPKFKLDQKYEMHELLRQMGI 357 V+L +++ LE + + + W + M+ R ++V+ P+ K+++KY + +L MGI Sbjct: 243 VLLPDEVSGLEQLESIINFEKLTEWTSSNVMEERKIKVYLPRMKMEEKYNLTSVLMAMGI 302 Query: 358 RRIFSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVD 417 +FS A+LS +S + +L++S+ + E++E G E V + + A S+ + D Sbjct: 303 TDVFSSSANLSGIS-SAESLKISQAVHAAHAEINEAGREVVGSAEAGVDAASVSEEFRAD 361 Query: 418 RPFHFMIYEETSGMLLFLGRVVNP 441 PF F I + +LF GR V+P Sbjct: 362 HPFLFCIKHIATNAVLFFGRCVSP 385 >2XN5-A nrPDB Length = 350 Score = 376 bits (965), Expect = e-104, Method: Composition-based stats. Identities = 109/348 (31%), Positives = 181/348 (52%), Gaps = 6/348 (1%) Query: 70 ASRQQLAKETSNFGFSLLRKISMR-HDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGL 128 A+ +++ ++F F+L R+ ++ D N+ FSP +S A+ L GA T+T+I L Sbjct: 6 ATLYKMSSINADFAFNLYRRFTVETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETL 65 Query: 129 HLQALKPTKPGLLPSLFKGLRETLS-RNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFD 187 L T + F+ L +L+ EL L G+ FI K F N K ++ Sbjct: 66 GFN-LTDTPMVEIQHGFQHLICSLNFPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYE 124 Query: 188 TECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFD 247 TE +F N S AK+ +N ++ +T+GK+ L ++ P T ++LV+YI FK +W PFD Sbjct: 125 TEVFSTDFSNISAAKQEINSHVEMQTKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFD 184 Query: 248 PVFTEV-DTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKM 306 P TE +F +DK T++VPMM+ ++ D C VL++ Y NA L VL K Sbjct: 185 PSKTEDSSSFLIDKTTTVQVPMMHQMEQYYHLVDMELNCTVLQMDYSKNALALFVLP-KE 243 Query: 307 GDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFAD 366 G ++E +++ ++ W R ++ +++F PKF + Y++ L +MGI+ +S AD Sbjct: 244 GQMESVEAAMSSKTLKKWNRLLQKGWVDLFVPKFSISATYDLGATLLKMGIQHAYSENAD 303 Query: 367 LSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVI 414 S L+ L++S + V+ + E+GTEA + E S+P Sbjct: 304 FSGLTEDN-GLKLSNAAHKAVLHIGEKGTEAAGAMFLEAIPRSIPNTF 350 >5INW-A nrPDB Length = 421 Score = 375 bits (962), Expect = e-104, Method: Composition-based stats. Identities = 109/386 (28%), Positives = 187/386 (48%), Gaps = 8/386 (2%) Query: 29 PETPAP-QNQTSRVVQAPKEEEEDEQEASEEKASEEEKAWLMASRQQLAKETSNFGFSLL 87 PE AP Q+ + + EE+ DE+E ++ K + Q++A + GF L Sbjct: 34 PEPLAPGQSPAASSEEGSSEEKGDEREPHGDEGKRGRKDKKKSKTQRIASAVNGLGFRLY 93 Query: 88 RKI--SMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQA-LKPTKPGLLPSL 144 +++ N+ FSP ++ A+ + GA G T ++ L + L K Sbjct: 94 KQVLGGAGPADNIFFSPLSIASALGVVTAGANGSTRAELDTALGFKEFLHGKKKAKSMKY 153 Query: 145 FKGLRETL-SRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAKR 203 F L L R+ L + F K + F F + ++F ++ A Sbjct: 154 FARLNGALYKRSAGFELMGKNVVFSKKGLWLYRQFTRTVAHLFKSNVRSVDFGDSKNAVE 213 Query: 204 LMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKT 263 LMN YI K T K P + +++ +T L++V+ I FKG W F+P T+ F ++ + Sbjct: 214 LMNAYIEKVTSKKFPDVISDVDTDTSLVIVNVIYFKGSWGNKFEPDLTKNVRFWVNSSYS 273 Query: 264 IKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLTTDLVET 323 + VP M+ K + T D+ R V+KLPY+G A+MLV++ + D +E+ ++ + +E Sbjct: 274 MMVPTMHQRAKLSYTQDRKLRSTVVKLPYEGGASMLVIVPHRTEDLPKVEESVSQEQLEE 333 Query: 324 WLRNMKTRN--MEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSR 381 WL + N +++ PKFK+ Y++ L MG+ +FS ADLS ++ + L V + Sbjct: 334 WLSLLGPSNHYVQLSLPKFKISVSYDLKAYLSAMGMSSMFSYGADLSRITGMQK-LHVDK 392 Query: 382 VLQRTVIEVDERGTEAVAGILSEITA 407 + ++V+ V+E GTEA A + I A Sbjct: 393 ITHKSVLHVNEEGTEAKAETVVGIMA 418 >2V95-A nrPDB Length = 371 Score = 373 bits (958), Expect = e-104, Method: Composition-based stats. Identities = 93/373 (24%), Positives = 197/373 (52%), Gaps = 9/373 (2%) Query: 71 SRQQLAKETSNFGFSLLRK-ISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLH 129 S + LA +F F+L ++ +++ D N + SP +S+A+ + LG+ +TQ + L Sbjct: 5 SHRGLAPTNVDFAFNLYQRLVALNPDKNTLISPVSISMALAMVSLGSA---QTQSLQSLG 61 Query: 130 LQALKPTKPGLLPSLFKGLRETLSR-NLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDT 188 L T + F+ L L + + L + G+ F+ + +K++F K+Y+++ Sbjct: 62 FN-LTETSEAEIHQSFQYLNYLLKQSDTGLEMNMGNAMFLLQKLKLKDSFLADVKQYYES 120 Query: 189 ECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDP 248 E + ++F + ++A + +N ++ +T+GKI +F +++ ILV+YI +G W PF P Sbjct: 121 EALAIDFEDWTKASQQINQHVKDKTQGKIEHVFSDLDSPASFILVNYIFLRGIWELPFSP 180 Query: 249 VFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGD 308 T + F++++ T+KVPMM +G D F C ++++ Y GN T +L ++ G Sbjct: 181 ENTREEDFYVNETSTVKVPMMVQSGSIGYFRDSVFPCQLIQMDYVGNGTAFFILPDQ-GQ 239 Query: 309 HLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLS 368 + L+ D ++ W + M R + ++ PKF + Y++ ++L + I+ + + +D S Sbjct: 240 MDTVIAALSRDTIDRWGKLMTPRQVNLYIPKFSMSDTYDLKDVLEDLNIKDLLTNQSDFS 299 Query: 369 ELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYEET 428 + L ++ ++ + ++++DE + + + S P IK ++PF +++++ Sbjct: 300 G-NTKDVPLTLT-MVHKAMLQLDEGNVLPNSTNGAPLHLRSEPLDIKFNKPFILLLFDKF 357 Query: 429 SGMLLFLGRVVNP 441 + L + +VVNP Sbjct: 358 TWSSLMMSQVVNP 370 >3LW2-A nrPDB Length = 379 Score = 372 bits (955), Expect = e-103, Method: Composition-based stats. Identities = 104/375 (27%), Positives = 184/375 (49%), Gaps = 13/375 (3%) Query: 76 AKETSNFGFSLLRKI-SMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALK 134 A + ++FG + +++ D N+VFSP+G+S + L + G T QI+ + + + Sbjct: 9 AHQATDFGVKVFQQVVQASKDRNVVFSPYGVSSVLAMLQMTTAGKTRRQIQDAMGFKVNE 68 Query: 135 PTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMN 194 L L K L ++N ++ F+ +D ++ + F + F T ++ Sbjct: 69 KGTAHALRQLSKELMGPWNKN---EISTADAIFVQRDLELVQGFMPHFFKLFQTMVKQVD 125 Query: 195 FRNASQAKRLMNHYINKETRGKIPKLFDE--INPETKLILVDYILFKGKWLTPFDPVFTE 252 F +A+ ++N ++ + T+G I L + ++ T+L+LV+ + F G+W TPF T Sbjct: 126 FSEVERARFIINDWVERHTKGMINDLLAKGAVDELTRLVLVNALYFSGQWKTPFLEASTH 185 Query: 253 VDTFHLDKYKTIKVPMMYGAGKFAST---FDKNFRCHVLKLPYQGNATMLVV--LMEKMG 307 FH T+ VPMM + KF T V++LPYQG+ + + EK Sbjct: 186 QRLFHKSDGSTVSVPMMAQSNKFNYTEFTTPDGLEYDVVELPYQGDTLSMFIAAPFEKDV 245 Query: 308 DHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPF-AD 366 AL + L +L+ W NM + PKF L+ + ++ L ++G+ +FS AD Sbjct: 246 HLSALTNILDAELIRQWKGNMTRLPRLLILPKFSLETEVDLRGPLEKLGMPDMFSATLAD 305 Query: 367 LSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYE 426 + LS + L V++ LQ+ IEV+E GT A + I+A P + +DR F F++ Sbjct: 306 FTSLSDQEQ-LSVAQALQKVRIEVNESGTVASSSTAFVISARMAPTEMVIDRSFLFVVRH 364 Query: 427 ETSGMLLFLGRVVNP 441 + +LF+G+V+ P Sbjct: 365 NPTETILFMGQVMEP 379 >4P0F-A nrPDB Length = 393 Score = 370 bits (949), Expect = e-103, Method: Composition-based stats. Identities = 104/381 (27%), Positives = 180/381 (47%), Gaps = 16/381 (4%) Query: 70 ASRQQLAKETSNFGFSLLRKISMRHDG-NMVFSPFGMSLAMTGLMLGATGPTETQIKRGL 128 A+ Q+ A+ + F ++ K+S + G N+VFSPF + LGA T TQ+ +GL Sbjct: 5 AAHQEFARRLALFSINVYGKLSGQKPGENIVFSPFSIQTCAAMARLGAENETATQLDQGL 64 Query: 129 HLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDT 188 L + S + L + L + F+ + +++ F L + F + Sbjct: 65 GL--ASSDPEQIAHSFHQVL---AAYQDSQILRIANKIFVMDGYQLRQEFDQLLSKQFLS 119 Query: 189 ECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDE--INPETKLILVDYILFKGKWLTPF 246 ++F QA +N+++ + T I L +N E++L+LV+ I FKG W F Sbjct: 120 AAQSVDFSKNVQAAATINNWVEQRTNHLIKDLVPADVLNSESRLVLVNAIHFKGTWQHQF 179 Query: 247 DPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQ-GNATMLVVLMEK 305 T DTFHLD +T++VPMM +F L+LPY+ + +ML+VL Sbjct: 180 AKHLTRPDTFHLDGERTVQVPMMSLKERFRYADLPALDAMALELPYKDSDLSMLIVLPNT 239 Query: 306 MGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFA 365 ALE+ L + +++ + + P+FK + + E+ E+ +++G+ R+FS A Sbjct: 240 KTGLPALEEKLRLTTLSQITQSLYETKVALKLPRFKAEFQVELSEVFQKLGMSRMFSDQA 299 Query: 366 DLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILS------EITAYSMPPVIKVDRP 419 + ++ + L+VS ++ + IEV+E GTEA A I + P D P Sbjct: 300 EFGKMLQSPEPLKVSAIIHKAFIEVNEEGTEAAAATGMAVRRKRAIMSPEEPIEFFADHP 359 Query: 420 FHFMIYEETSGMLLFLGRVVN 440 F +++ + + LF G VV Sbjct: 360 FTYVLVHQKD-LPLFWGSVVR 379 >4KDS-A nrPDB Length = 386 Score = 367 bits (942), Expect = e-102, Method: Composition-based stats. Identities = 102/381 (26%), Positives = 188/381 (49%), Gaps = 16/381 (4%) Query: 70 ASRQQLAKETSNFGFSLLRKISMRHDG-NMVFSPFGMSLAMTGLMLGATGPTETQIKRGL 128 A+ L ++ ++FG + +++ G N+ FSP+G++ + LGA G T + L Sbjct: 10 AAISNLQEKQTDFGMRVFSQVAQNSKGSNLAFSPYGVATILAMAQLGAGGNTLKTLNAKL 69 Query: 129 HLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDT 188 + L + + E G+ S + + +++ F + F Sbjct: 70 GFSLQERGMARQQRLLQRDIS------SEEGVELASGVMVERKMALEKGFRRGLGKAFQA 123 Query: 189 ECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDE--INPETKLILVDYILFKGKWLTPF 246 ++F QA ++N +++ T G IP + ET+++L++ + F+G W PF Sbjct: 124 SPHQLDFSRPDQALDIINAWVSDHTAGTIPSFLSSGALTDETRMVLLNALHFQGLWKVPF 183 Query: 247 DPVFTEVDTFHLDKYKTIKVPMMYGAGKFAST---FDKNFRCHVLKLPYQGNA-TMLVVL 302 DP TE FH ++ VPMM +F V+++PY+G + +ML+V Sbjct: 184 DPKMTEERLFHCANGSSVPVPMMRLTHRFKYGEFVTPDGVDYDVIEVPYEGESLSMLLVS 243 Query: 303 M-EKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIF 361 E +L LTT ++ W + M++ ++ P+F LD + E+ +L QMG+ +F Sbjct: 244 PFEPETPVSSLSSELTTQRLQQWRQEMRSVKRQLVLPRFTLDSEVELKSILIQMGLGDMF 303 Query: 362 S-PFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPF 420 + AD + ++ T + L VS+VLQ+ IEV+E GT+A A + + + I ++RPF Sbjct: 304 NLAKADFTRIT-TEQPLCVSKVLQKVKIEVNEEGTKASAATAAILFSRMAVEEITMNRPF 362 Query: 421 HFMIYEETSGMLLFLGRVVNP 441 F+I+ +++G +LF+G+V P Sbjct: 363 LFLIHHKSTGAVLFMGQVNQP 383 >4DY0-A nrPDB Length = 379 Score = 366 bits (940), Expect = e-101, Method: Composition-based stats. Identities = 107/377 (28%), Positives = 187/377 (49%), Gaps = 15/377 (3%) Query: 75 LAKETSNFGFSLLRKISMRHD-GNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQAL 133 L + SN G + +I N+V SP G++ + L LGA G T+ Q+ + Sbjct: 8 LEELGSNTGIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRY--- 64 Query: 134 KPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPM 193 G+ L K + +S+ + +T + F+ +++ F +K F E + Sbjct: 65 --GVNGVGKILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNV 122 Query: 194 NFRNASQAKRLMNHYINKETRGKIPKLFDE--INP-ETKLILVDYILFKGKWLTPFDPVF 250 NF + + A +N ++ ETR I L I+ T+L+LV+ + FKG W + F P Sbjct: 123 NFEDPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPEN 182 Query: 251 TEVDTFHLDKYKTIKVPMMYGAGKFA---STFDKNFRCHVLKLPYQGNA-TMLVVLMEKM 306 T+ TF K+ +VPM+ F ++ + + ++LPY G + +ML+ L + Sbjct: 183 TKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALPTES 242 Query: 307 G-DHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIF-SPF 364 A+ +++T +++W+ M + ++V PKF + ++ E L+ +GI +F S Sbjct: 243 STPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSK 302 Query: 365 ADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMI 424 A+ ++++ NL VS +LQ+ IEV E GT+A A + + A S PP VDRPF F I Sbjct: 303 ANFAKITTGSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSSPPWFIVDRPFLFFI 362 Query: 425 YEETSGMLLFLGRVVNP 441 +G +LF+G++ P Sbjct: 363 RHNPTGAVLFMGQINKP 379 >2H4Q-A nrPDB Length = 382 Score = 363 bits (932), Expect = e-101, Method: Composition-based stats. Identities = 97/351 (27%), Positives = 172/351 (49%), Gaps = 18/351 (5%) Query: 68 LMASRQQLAKETSNFGFSLLRKISM-RHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKR 126 L S +Q++ NF L K++ D N+ FSP+ +S A+ L A G T ++ Sbjct: 38 LEISMEQVSASIGNFTVDLFNKLNETNRDKNIFFSPWSISSALALTYLAAKGSTAREMAE 97 Query: 127 GLHLQALKPTKPGLLPSLFKGLRETLSRN-LELGLTQGSFAFIHKDFDVKETFFNLSKRY 185 LH + + + S FK L ++ L + ++ K + + T+ LSK+Y Sbjct: 98 VLHFEQAEN-----IHSGFKELLTAFNKPRNNYSLRSANRIYVEKTYALLPTYLQLSKKY 152 Query: 186 FDTECVPMNFRN-ASQAKRLMNHYINKETRGKIPKLF--DEINPETKLILVDYILFKGKW 242 + E +NF+ Q+++ +N ++ K+T KI L D++ T+LILV+ I FK +W Sbjct: 153 YKAEPQKVNFKTAPEQSRKEINTWVEKQTESKIKNLLSSDDVKATTRLILVNAIYFKAEW 212 Query: 243 LTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPY-QGNATMLVV 301 F T + F L K K+ V MMY F + +++LPY + +M ++ Sbjct: 213 EVKFQAEKTSIQPFRLSKNKSKPVKMMYMRDTFPVLIMEKMNFKMIELPYVKRELSMFIL 272 Query: 302 LMEKM----GDHLALEDYLTTDLVETW--LRNMKTRNMEVFFPKFKLDQKYEMHELLRQM 355 L + + LE LT + + W + M +++ PKF L+ + ++ + LR M Sbjct: 273 LPDDIKDGTTGLEQLERELTYERLSEWADSKMMTETLVDLHLPKFSLEDRIDLRDTLRNM 332 Query: 356 GIRRIFSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEIT 406 G+ F+ AD ++ ++L +S+V+ ++ + VDE+GTEAVA I+ Sbjct: 333 GMTTAFTTNADFRGMTD-KKDLAISKVIHQSFVAVDEKGTEAVAATAVIIS 382 >1HLE-A nrPDB Length = 345 Score = 357 bits (917), Expect = 4e-99, Method: Composition-based stats. Identities = 90/333 (27%), Positives = 172/333 (51%), Gaps = 19/333 (5%) Query: 72 RQQLAKETSNFGFSLLRKISMR-HDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHL 130 +QL+ ++F L R ++ GN+ SP +S A+ + LG G T Q+ + L+ Sbjct: 2 MEQLSTANTHFAVDLFRALNESDPTGNIFISPLSISSALAMIFLGTRGNTAAQVSKALYF 61 Query: 131 QALKPTKPGLLPSLFKGLRETLSRN-LELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTE 189 ++ + S F+ L +++ L + + K ++ F +++ + E Sbjct: 62 DTVED-----IHSRFQSLNADINKPGAPYILKLANRLYGEKTYNFLADFLASTQKMYGAE 116 Query: 190 CVPMNFRN-ASQAKRLMNHYINKETRGKIPKLFDE--INPETKLILVDYILFKGKWLTPF 246 ++F+ A++ +N ++ +T GKIP+L + ++ TKL+LV+ I FKG W F Sbjct: 117 LASVDFQQAPEDARKEINEWVKGQTEGKIPELLVKGMVDNMTKLVLVNAIYFKGNWQQKF 176 Query: 247 DPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNA-TMLVVLMEK 305 T F L+K T V MMY KF + ++ +C VL+LPYQG +M+++L + Sbjct: 177 MKEATRDAPFRLNKKDTKTVKMMYQKKKFPYNYIEDLKCRVLELPYQGKELSMIILLPDD 236 Query: 306 MGD----HLALEDYLTTDLVETWLR--NMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRR 359 + D +E LT D + W + N+ + V P+FKL++ Y++ L ++G++ Sbjct: 237 IEDESTGLEKIEKQLTLDKLREWTKPENLYLAEVNVHLPRFKLEESYDLTSHLARLGVQD 296 Query: 360 IFS-PFADLSELSATGRNLQVSRVLQRTVIEVD 391 +F+ ADLS +S R+L VS+++ ++ ++++ Sbjct: 297 LFNRGKADLSGMSG-ARDLFVSKIIHKSFVDLN 328 >2H4P-A nrPDB Length = 394 Score = 356 bits (914), Expect = 9e-99, Method: Composition-based stats. Identities = 96/374 (25%), Positives = 170/374 (45%), Gaps = 36/374 (9%) Query: 68 LMASRQQLAKETSNFGFSLLRKISM-RHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKR 126 L S +Q++ NF L K++ D N+ FSP+ +S A+ L A G T ++ Sbjct: 22 LEISMEQVSASIGNFTVDLFNKLNETNRDKNIFFSPWSISSALALTYLAAKGSTAREMAE 81 Query: 127 GLHLQALKPTKPGL-----------------------LPSLFKGLRETLSRN-LELGLTQ 162 LH + + S FK L ++ L Sbjct: 82 VLHFTEAVRAESSSVARPSRGRPKRRRMDPEHEQAENIHSGFKELLTAFNKPRNNYSLRS 141 Query: 163 GSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRN-ASQAKRLMNHYINKETRGKIPKLF 221 + ++ K + + T+ LSK+Y+ E +NF+ Q+++ +N ++ K+T KI L Sbjct: 142 ANRIYVEKTYALLPTYLQLSKKYYKAEPQKVNFKTAPEQSRKEINTWVEKQTESKIKNLL 201 Query: 222 --DEINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTF 279 D++ T+LILV+ I FK +W F T + F L K K+ V MMY F Sbjct: 202 SSDDVKATTRLILVNAIYFKAEWEVKFQAEKTSIQPFRLSKNKSKPVKMMYMRDTFPVLI 261 Query: 280 DKNFRCHVLKLPY-QGNATMLVVLMEKM----GDHLALEDYLTTDLVETW--LRNMKTRN 332 + +++LPY + +M ++L + + LE LT + + W + M Sbjct: 262 MEKMNFKMIELPYVKRELSMFILLPDDIKDGTTGLEQLERELTYERLSEWADSKMMTETL 321 Query: 333 MEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSRVLQRTVIEVDE 392 +++ PKF L+ + ++ + LR MG+ F+ AD ++ ++L +S+V+ ++ + VDE Sbjct: 322 VDLHLPKFSLEDRIDLRDTLRNMGMTTAFTTNADFRGMTD-KKDLAISKVIHQSFVAVDE 380 Query: 393 RGTEAVAGILSEIT 406 +GTEA A I+ Sbjct: 381 KGTEAAAATAVIIS 394 >4DTE-A nrPDB Length = 374 Score = 355 bits (910), Expect = 3e-98, Method: Composition-based stats. Identities = 96/376 (25%), Positives = 179/376 (47%), Gaps = 16/376 (4%) Query: 75 LAKETSNFGFSLLRK-ISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQAL 133 + + ++FG + + + D N+ SP+G++ + +GA G T + + Sbjct: 3 IQDKQTDFGLQVFAEAVQSAPDRNLALSPYGIASVLGMAQMGAYGATLKLLASKMGYSL- 61 Query: 134 KPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPM 193 + +P L + L+ L+ E G+ S + + +++ F + F + + Sbjct: 62 ---QERGMPKLQRLLQRDLAS--EDGVEVASGVMVDRKIILEKVFRRSLSKAFQSVPHQI 116 Query: 194 NFRNASQAKRLMNHYINKETRGKIPKLFDE--INPETKLILVDYILFKGKWLTPFDPVFT 251 +F A++++N + + T G I + ++ T+L+ ++ + F G W TPFDP T Sbjct: 117 DFSQPEMARQVINSWTSDHTDGMISEFLPSGVLSELTRLVFLNALHFHGVWKTPFDPRNT 176 Query: 252 EVDTFHLDKYKTIKVPMMYGAGKFAST---FDKNFRCHVLKLPYQGNA-TMLVVLMEKMG 307 FH + VPMM KF V+++PY+G + +ML+V + Sbjct: 177 REQLFHTVNGSAVSVPMMTTTQKFNYGEFVSKDGVDYDVIEMPYEGESISMLLVTPFEKD 236 Query: 308 -DHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPF-A 365 AL L++ + W + M+ + ++ P+F +D + ++ L +MG+ IFS A Sbjct: 237 VPLSALNKELSSSRIHQWRQEMRKISKQLSIPRFSMDTEIDLKSTLSRMGLGDIFSQSRA 296 Query: 366 DLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIY 425 D S ++ T L VS+VLQR +EV+E GT+ + + I + I +DRPF F+I Sbjct: 297 DFSRIT-TEEPLCVSKVLQRVKLEVNEEGTKGSSATAAVIYSRMAVEEITLDRPFFFLIQ 355 Query: 426 EETSGMLLFLGRVVNP 441 + +G LLF G++ P Sbjct: 356 HKPTGALLFSGQLTQP 371 >6F4U-A nrPDB Length = 341 Score = 352 bits (904), Expect = 2e-97, Method: Composition-based stats. Identities = 88/324 (27%), Positives = 156/324 (48%), Gaps = 8/324 (2%) Query: 74 QLAKETSNFGFSLLRKISMRHDG-NMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQA 132 ++A ++F F I+ G N+ FSP +S A L LGA + +QI GL Sbjct: 4 KIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNL 63 Query: 133 LKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVP 192 + ++ + L L GS F+ + F N + ++ + Sbjct: 64 TELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFH 123 Query: 193 MNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTE 252 NF + +L+N ++ KETRGKI L E+ + ++LV+YI FK W PF T Sbjct: 124 TNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTT 183 Query: 253 VDTFHLDKYKTIKVPMMYGAGKFA-STFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLA 311 F++D+ T++VPMM + D+ C VL++ Y+G+AT+ +L + G Sbjct: 184 PKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQ-GKMRE 242 Query: 312 LEDYLTTDLVETWLRNMKTR----NMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADL 367 +E+ LT +++ W ++ R +E+ PKF + Y + ++L ++G +FS +ADL Sbjct: 243 IEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADL 302 Query: 368 SELSATGRNLQVSRVLQRTVIEVD 391 S ++ + L+ S+ + ++VD Sbjct: 303 SGITKQQK-LEASKSFHKATLDVD 325 >5NCS-A nrPDB Length = 375 Score = 350 bits (897), Expect = 1e-96, Method: Composition-based stats. Identities = 92/374 (24%), Positives = 174/374 (46%), Gaps = 17/374 (4%) Query: 73 QQLAKETSNFGFSLLRKISMR-HDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQ 131 +++ K+ + F F LL+ + N+ SP +S+A+ + GA G T ++K L Sbjct: 6 EKIEKDNA-FAFDLLQTTRKHVTEANVFISPLSVSMALNMTLNGAAGVTADEMKTALR-- 62 Query: 132 ALKPTKPGLLPSLFKGLRE-TLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTEC 190 + LRE L + + + + + VKE F ++ ++D E Sbjct: 63 -ETGYTMEDINEYSHSLREALLKVDPSTTIGMANSIWYKQGELVKEPFILANRTHYDAEV 121 Query: 191 VPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVF 250 ++F + + +N + ++T KI K+ D I + L++ + FKG W+T F Sbjct: 122 KAVDFSSPATLPA-INGWCAQKTNDKITKILDYIPGNAFMYLINAVYFKGIWVTQFKKSD 180 Query: 251 TEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHL 310 T+ F T +V MM F T D+ C L++ Y A ++V++ G Sbjct: 181 TKRAPFRKADGTTQEVNMMAQKSTFGYTTDEC--CQYLEMDYGNKAFSMIVMLPNEGQTT 238 Query: 311 A-LEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEM-HELLRQMGIRRIFSPFADLS 368 + + L ++ ++ + + P+FK + KY + ++L +MG+ F+ AD Sbjct: 239 RDVIEQLDNKHWSMIIKGIRPTQVSLRMPRFKTECKYGLEKKILPEMGMNVPFTETADFP 298 Query: 369 ELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPV----IKVDRPFHFMI 424 ++ + +SRV+ +T ++VDE GTEA A E+ S P +++PF F I Sbjct: 299 GITDAA--IFISRVIHKTFVQVDEEGTEAAAVTAVEMVKTSSPSTTPINFHINKPFVFAI 356 Query: 425 YEETSGMLLFLGRV 438 E+++G++LF+G + Sbjct: 357 REKSTGVILFIGEI 370 >3ZHA-A nrPDB Length = 392 Score = 341 bits (874), Expect = 4e-94, Method: Composition-based stats. Identities = 92/378 (24%), Positives = 175/378 (46%), Gaps = 8/378 (2%) Query: 68 LMASRQQLAKETSNFGFSLLRKISMRHD-GNMVFSPFGMSLAMTGLMLGATGPTETQIKR 126 L LA+ ++ FSL + ++ N++ SP ++ ++ + LG T +Q K Sbjct: 2 LSPKAATLAERSAGLAFSLYQAMAKDQAVENILLSPVVVASSLGLVSLGGKATTASQAKA 61 Query: 127 GLHLQALKPTK-PGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRY 185 L + L+ + L L + L + +RN+ L GS + E F SK++ Sbjct: 62 VLSAEQLRDEEVHAGLGELLRSLSNSTARNVTWKL--GSRLYGPSSVSFAEDFVRSSKQH 119 Query: 186 FDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTP 245 ++ E +NFR+ A + +N + + T GK+P++ ++ +LV+ + FK W Sbjct: 120 YNCEHSKINFRDKRSALQSINEWAAQTTDGKLPEVTKDVERTDGALLVNAMFFKPHWDEK 179 Query: 246 FDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVL-ME 304 F + F + + T+ V MM+ G + D+ + ++++P + L++L Sbjct: 180 FHHKMVDNRGFMVTRSYTVGVTMMHRTGLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPH 239 Query: 305 KMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRR-IFSP 363 + LE LT + ++ W+ M+ + + + PK ++ +++ + L +G+ I Sbjct: 240 HVEPLERLEKLLTKEQLKIWMGKMQKKAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKN 299 Query: 364 FADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFM 423 ADLS +S ++L ++ V T E D G I S P + D PF F+ Sbjct: 300 KADLSRMSG-KKDLYLASVFHATAFEWDTEGNPFDQDIYGREELRS-PKLFYADHPFIFL 357 Query: 424 IYEETSGMLLFLGRVVNP 441 + + SG LLF+GR+V P Sbjct: 358 VRDTQSGSLLFIGRLVRP 375 >3F02-A nrPDB Length = 359 Score = 340 bits (872), Expect = 8e-94, Method: Composition-based stats. Identities = 84/342 (24%), Positives = 168/342 (49%), Gaps = 13/342 (3%) Query: 77 KETSNFGFSLLRKI-SMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKP 135 + ++ ++ ++ + D N++FSP ++LAM + LGA G T+ +I+ + +LK Sbjct: 21 EAIADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKN 80 Query: 136 TKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNF 195 + F + ++ + + + F+ F V E F + K+YF+ ++F Sbjct: 81 GEEFSFLKEFSNM--VTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDF 138 Query: 196 RNASQAKRLMNHYINKETRGKIPKLFD--EINPETKLILVDYILFKGKWLTPFDPVFTEV 253 +N ++ T + L + + T L L++ + FKG W + F P T Sbjct: 139 SQNVAVANYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTRT 198 Query: 254 DTFHLDKYKTIKVPMMYGAGKFAST------FDKNFRCHVLKLPYQGNA-TMLVVLMEKM 306 +F D +++PMMY G+F + VL++PY+G+ +M++VL + Sbjct: 199 FSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQE 258 Query: 307 GDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFAD 366 LE + LVE W ++K + +EV+ P+F ++Q+ ++ ++L+ +GI IF A+ Sbjct: 259 VPLATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIKDAN 318 Query: 367 LSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAY 408 L+ LS + + +S+ + ++ +EV+E G+EA A + Sbjct: 319 LTGLSD-NKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISR 359 >1IMV-A nrPDB Length = 398 Score = 336 bits (862), Expect = 1e-92, Method: Composition-based stats. Identities = 104/403 (25%), Positives = 197/403 (48%), Gaps = 11/403 (2%) Query: 42 VQAPKEEEEDEQEASEEKASEEEKAWLMASRQQLAKETSNFGFSLLR-KISMRHDGNMVF 100 A EE S EEE + +LA SNFG+ L R + SM N++ Sbjct: 1 NPASPPEEGSPDPDSTGALVEEEDPFFKVPVNKLAAAVSNFGYDLYRVRSSMSPTTNVLL 60 Query: 101 SPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSRNLELGL 160 SP ++ A++ L LGA TE+ I R L+ + + +K L +T++ + L Sbjct: 61 SPLSVATALSALSLGADERTESIIHRALYYDLI---SSPDIHGTYKELLDTVTAP-QKNL 116 Query: 161 TQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKL 220 S K +K +F ++ + T + N + +N+++ + +GK+ + Sbjct: 117 KSASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLT-GNPRLDLQEINNWVQAQMKGKLARS 175 Query: 221 FDEINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYG-AGKFASTF 279 EI E ++L+ FKG+W+T FD T ++ F+LD+ +T++VPMM Sbjct: 176 TKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFYLDEERTVRVPMMSDPKAVLRYGL 235 Query: 280 DKNFRCHVLKLPYQGNATMLVVLMEKMGDHLAL-EDYLTTDLVETWLRNMKTRNMEVFFP 338 D + C + +LP G+ +++ L K+ +L L E+ LT++ + R +KT + P Sbjct: 236 DSDLSCKIAQLPLTGSMSIIFFLPLKVTQNLTLIEESLTSEFIHDIDRELKTVQAVLTVP 295 Query: 339 KFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAV 398 K KL + E+ + L++M ++ +F D S+++ G+ +++++V R E +E G Sbjct: 296 KLKLSYEGEVTKSLQEMKLQSLFDS-PDFSKIT--GKPIKLTQVEHRAGFEWNEDGAGTT 352 Query: 399 AGILSEITAYSMPPVIKVDRPFHFMIYEETSGMLLFLGRVVNP 441 + + P +++PF F++ + +G LLF+G++++P Sbjct: 353 PSPGLQPAHLTFPLDYHLNQPFIFVLRDTDTGALLFIGKILDP 395 >3OZQ-A nrPDB Length = 376 Score = 334 bits (856), Expect = 6e-92, Method: Composition-based stats. Identities = 97/377 (25%), Positives = 183/377 (48%), Gaps = 18/377 (4%) Query: 70 ASRQQLAKETSNFGFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLH 129 A+ Q+ ++F S+ +++ N + SPF + + G G T +I++ LH Sbjct: 6 ATLQEFPNAVNSFTPSVYKEVLKTEKANFLVSPFSAATLLALAQSGCRGDTAEEIRQVLH 65 Query: 130 LQALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTE 189 + G + + L N E L + ++ +F V+E F ++ + + Sbjct: 66 FVGDREKAEGAVKEVLSKLT-----NEEYTLHTANKIYVKTNFSVREEFQKIAVEVYGAQ 120 Query: 190 CVPMNFRNASQAKRLMNHYINKETRGKIPKLFDE--INPETKLILVDYILFKGKWLTPFD 247 ++F + A +LMN ++ ++T+ KI L D +N T+++L++ + F KWL PF Sbjct: 121 SENVDFSEKNDAAKLMNAWVEEQTQHKIQNLVDPEILNNLTRVVLINALYFNAKWLVPFP 180 Query: 248 PVFTEVDTFHLDKYKTIKVPMMYGAGK-FASTFDKNFRCHVLKLPYQGNATMLVVLMEKM 306 P T FH + ++V MY + F + +L+LP++G A++ +VL ++ Sbjct: 181 PFHTRKSDFHKSAKEVVQVDTMYLDEQYFNYYECHHLDAKLLELPFKGGASLTIVLSNQI 240 Query: 307 GDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFAD 366 ++LE + + N+ + + V PKFK++ + ++L+++G+++ F AD Sbjct: 241 EGLVSLESKIKRSFLP---HNLTKQLVNVALPKFKIESTVDFKKVLKKLGVKKAFGDEAD 297 Query: 367 LSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILS-----EITAYSMPPVIKVDRPFH 421 LS ++ +L +S ++Q++ I+V E G EA A E+ P VD PF Sbjct: 298 LSGIAGEKGDLVISNIVQKSFIDVSEEGVEAAAATYIPVILPEMALPDSPKQFIVDHPFI 357 Query: 422 FMIYEETSGMLLFLGRV 438 F I + GM+LF GRV Sbjct: 358 FYI--KVKGMILFAGRV 372 >2R9Y-A nrPDB Length = 430 Score = 324 bits (831), Expect = 5e-89, Method: Composition-based stats. Identities = 105/375 (28%), Positives = 177/375 (47%), Gaps = 18/375 (4%) Query: 71 SRQQLAKETSNFGFSLLRKISM-RHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLH 129 ++LA+ F L ++ N+V SP ++LA++ L LGA T + R LH Sbjct: 17 ETRRLAQAMMAFTTDLFSLVAQTSTSSNLVLSPLSVALALSHLALGAQNQTLHSLHRVLH 76 Query: 130 LQALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTE 189 + P LL ++ L + + ++ K F +K+ F S+R F + Sbjct: 77 MNT-GSCLPHLLSHFYQNLGPGT-------IRLAARIYLQKGFPIKDDFLEQSERLFGAK 128 Query: 190 CVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPV 249 V + + +N ++ + T GKI E+ T L+L++ I F G W T FDP Sbjct: 129 PVKLTGKQEEDLAN-INQWVKEATEGKIEDFLSELPDSTVLLLLNAIHFHGFWRTKFDPS 187 Query: 250 FTEVDTFHLDKYKTIKVPMMYGAGK-FASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGD 308 T+ D FHLD+ T+ V MM+ + V P++ N + +VV+ Sbjct: 188 LTQKDFFHLDERFTVSVDMMHAVSYPLRWFLLEQPEIQVAHFPFKNNMSFVVVMPTYFEW 247 Query: 309 HLA-LEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADL 367 +++ + LT D + + +++ R +V+ PK L Q+ ++ L Q+G++ +F DL Sbjct: 248 NVSEVLANLTWDTL--YHPSLQERPTKVWLPKLHLQQQLDLVATLSQLGLQELF-QGPDL 304 Query: 368 SELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYEE 427 +S +NL VS V ++ +E+ E G EA A + S+ V+RPF F I E+ Sbjct: 305 RGISE--QNLVVSSVQHQSTMELSEAGVEAAAATSVAMNRMSLSS-FTVNRPFLFFIMED 361 Query: 428 TSGMLLFLGRVVNPT 442 T G+ LF+G V NP Sbjct: 362 TIGVPLFVGSVRNPN 376 >1XQJ-A nrPDB Length = 389 Score = 321 bits (822), Expect = 4e-88, Method: Composition-based stats. Identities = 87/391 (22%), Positives = 179/391 (45%), Gaps = 21/391 (5%) Query: 64 EKAWLMASRQQLAKETSNFGFSLLRKISMRHD-GNMVFSPFGMSLAMTGLMLGATGPTET 122 E + S L S F L +++S + GN++FSP +S +++ +GA G T Sbjct: 7 ENLYFQGSMDALQLANSAFAVDLFKQLSEKEPLGNVLFSPIALSTSLSLAQVGAKGDTAN 66 Query: 123 QIKRGLHLQALKPTKPGLLPSLFKGLRETLSRNLE-LGLTQGSFAFIHKDFDVKETFFNL 181 +I + LH + +K G F+ + +++ L ++ K ++ F + Sbjct: 67 EIGQVLHFENVKDVPFG-----FQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISS 121 Query: 182 SKRYFDTECVPMNFRNA-SQAKRLMNHYINKETRGKIPKLF--DEINPETKLILVDYILF 238 +KR + E ++F++ + K +N+ I T G + + +N +TK+++V+ F Sbjct: 122 TKRPYAKELETVDFKDKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYF 181 Query: 239 KGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATM 298 GKW+ F T+ F ++K T V MM F+ + +++LP+Q Sbjct: 182 VGKWMKKFSESETKESPFRVNKTDTKPVQMMNMEATFSMGNIDSINSKIIELPFQNKHLS 241 Query: 299 LVVLMEK-----MGDHLALEDYLTTDLVETWLR--NMKTRNMEVFFPKFKLDQKYEMHEL 351 + +L+ K +E L ++ + W M +++ PKFK+++ + Sbjct: 242 MFILLPKDVEDESTGLEKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDPKAS 301 Query: 352 LRQMGIRRIFSP-FADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSM 410 L +G++ IFS +D S +S T + + +S V+ + +E+ E G +++ + I + Sbjct: 302 LENLGLKHIFSEDTSDFSGMSET-KGVALSNVIHKVSLEITEDGGDSIEVPGARILQHK- 359 Query: 411 PPVIKVDRPFHFMIYEETSGMLLFLGRVVNP 441 + D PF ++I + ++F G+ +P Sbjct: 360 -DELNADHPFIYIIRHNKTRNIIFFGKFSSP 389 >1K9O-I nrPDB Length = 378 Score = 318 bits (814), Expect = 4e-87, Method: Composition-based stats. Identities = 101/379 (26%), Positives = 182/379 (48%), Gaps = 16/379 (4%) Query: 72 RQQLAKETSN-FGFSLLRKISMRHDG-NMVFSPFGMSLAMTGLMLGATGPTETQIKRGLH 129 Q++ +E+++ F + ++ + G N+V S F + + L L + G + ++ R L Sbjct: 7 LQKILRESNDQFTAQMFSEVVKANPGQNVVLSAFSVLPPLGQLALASVGESHDELLRALA 66 Query: 130 LQALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTE 189 L TK F L + + L S ++ K ++ + F +S+ F +E Sbjct: 67 LPNDNVTKDV-----FADLNRGVRAVKGVDLKMASKIYVAKGLELNDDFAAVSRDVFGSE 121 Query: 190 CVPMNFRNASQAKRLMNHYINKETRGKIPKLFDE--INPETKLILVDYILFKGKWLTPFD 247 ++F + +A +N ++ +T +I L D ++ T+ +LV+ I FKG W F Sbjct: 122 VQNVDFVKSVEAAGAINKWVEDQTNNRIKNLVDPDALDETTRSVLVNAIYFKGSWKDKFV 181 Query: 248 PVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGN-ATMLVVLMEKM 306 T FH+ K KTIKVP M G ++++ Y+G+ A+M+++L ++ Sbjct: 182 KERTMDRDFHVSKDKTIKVPTMIGKKDVRYADVPELDAKMIEMSYEGDQASMIIILPNQV 241 Query: 307 GDHLALEDYLT-TDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPF- 364 ALE L + + +E+ PKFK++ ++ E+L M I+++F+P Sbjct: 242 DGITALEQKLKDPKALSRAEERLYNTEVEITLPKFKIETTTDLKEVLSNMNIKKLFTPGA 301 Query: 365 ADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMP--PVIKVDRPFHF 422 A L L T +L V +Q+ IEV+E G EA A I S+ P + +DRPF+F Sbjct: 302 ARLENLLKTKESLTVDAAIQKAFIEVNEEGAEAAAANAFGIVPKSLILYPEVHIDRPFYF 361 Query: 423 MIYEETSGMLLFLGRVVNP 441 + + G+ +F G+V+ P Sbjct: 362 EL--KIDGIPMFNGKVIEP 378 >6CJ7-A nrPDB Length = 390 Score = 317 bits (813), Expect = 5e-87, Method: Composition-based stats. Identities = 99/375 (26%), Positives = 186/375 (49%), Gaps = 15/375 (4%) Query: 77 KETSNFGFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPT 136 +++FG ++ ++++ GN+ SPF +++ + L GA G T +I R L + K Sbjct: 15 PASTSFGVNVFKQMATEQSGNLAASPFSITILLAMLQQGAAGNTLDEITRALQMTPEKSA 74 Query: 137 KPGLLPSLFKGLRETLS-RNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNF 195 + +FK + E + RN L + F+ ++F++ F ++ FD++ P F Sbjct: 75 E------IFKKVNEEIQKRNSRNILKTANNVFLSENFNLNPQFKRIAVNNFDSDLTPTYF 128 Query: 196 RNASQAKRLMNHYINKETRGKIPKLF--DEINPETKLILVDYILFKGKWLTPFDPVFTEV 253 + A + +N +I +T KI KL D+++ T++++V+ + FKG W PF T+ Sbjct: 129 GKPALAAQNINSWIASKTNDKIDKLVSPDDLSGNTQMVMVNAVYFKGLWEIPFREQATQK 188 Query: 254 DTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNA-TMLVVLMEKMGDHLAL 312 F L+ + M F + K V+ LP++ N +++VVL K + AL Sbjct: 189 RNFTLNGGEKKVASFMQTRRYFKAGTHKPAMAKVVVLPFEYNEYSLIVVLPLKSSNVDAL 248 Query: 313 EDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSA 372 L+ + V ++L + +++ + PKF + + +L +MG+ IF+ A+L L + Sbjct: 249 LSSLSMEDVASFLD-LPPKDVALELPKFSIKADINLEPVLNKMGVSSIFTQQAELYNLGS 307 Query: 373 TGR-NLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPP---VIKVDRPFHFMIYEET 428 G + QVS L V+ +DERG A A A S + ++PF ++++ Sbjct: 308 HGSLSPQVSSALHSAVLTIDERGGSAAAATSFAAVALSYDEPSLYFRANKPFLAILWDNR 367 Query: 429 SGMLLFLGRVVNPTL 443 S + LF+ R+++PTL Sbjct: 368 SSIPLFMARIMDPTL 382 >1SEK-A nrPDB Length = 378 Score = 314 bits (804), Expect = 6e-86, Method: Composition-based stats. Identities = 101/379 (26%), Positives = 182/379 (48%), Gaps = 16/379 (4%) Query: 72 RQQLAKETSN-FGFSLLRKISMRHDG-NMVFSPFGMSLAMTGLMLGATGPTETQIKRGLH 129 Q++ +E+++ F + ++ + G N+V S F + + L L + G + ++ R L Sbjct: 7 LQKILRESNDQFTAQMFSEVVKANPGQNVVLSAFSVLPPLGQLALASVGESHDELLRALA 66 Query: 130 LQALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTE 189 L TK F L + + L S ++ K ++ + F +S+ F +E Sbjct: 67 LPNDNVTKDV-----FADLNRGVRAVKGVDLKMASKIYVAKGLELNDDFAAVSRDVFGSE 121 Query: 190 CVPMNFRNASQAKRLMNHYINKETRGKIPKLFDE--INPETKLILVDYILFKGKWLTPFD 247 ++F + +A +N ++ +T +I L D ++ T+ +LV+ I FKG W F+ Sbjct: 122 VQNVDFVKSVEAAGAINKWVEDQTNNRIKNLVDPDALDETTRSVLVNAIYFKGSWKDKFN 181 Query: 248 PVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGN-ATMLVVLMEKM 306 T FH+ K KTIKVP M G ++++ Y+G+ A+M+++L ++ Sbjct: 182 KERTMDRDFHVSKDKTIKVPTMIGKKDVRYADVPELDAKMIEMSYEGDQASMIIILPNQV 241 Query: 307 GDHLALEDYLT-TDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPF- 364 ALE L + + +E++ PKFK++ ++ E+L M I+++F+P Sbjct: 242 DGITALEQKLKDPKALSRAEERLYNTEVEIYLPKFKIETTTDLKEVLSNMNIKKLFTPGA 301 Query: 365 ADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYS--MPPVIKVDRPFHF 422 A L L T +L V +Q+ IEV+E G EA A +IT YS P +++++PF F Sbjct: 302 ARLENLLKTKESLYVDAAIQKAFIEVNEEGAEAAAANAFKITTYSFHFVPKVEINKPFFF 361 Query: 423 MIYEETSGMLLFLGRVVNP 441 + + M F G V P Sbjct: 362 SLKYNRNSM--FSGVCVQP 378 >3PZF-A nrPDB Length = 397 Score = 312 bits (799), Expect = 2e-85, Method: Composition-based stats. Identities = 95/379 (25%), Positives = 175/379 (46%), Gaps = 13/379 (3%) Query: 77 KETSNFGFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGAT---GPTETQIKRGLHLQAL 133 + + F +++I H+ N+V SPF + + +T + + G + KR L + Sbjct: 20 QRQNEFDLMFVKEIFKNHNSNVVLSPFSVKILLTLIYEASDTSFGNAVSNTKRELS-SVI 78 Query: 134 KPTKPGLLPSLFKGLRETLSR-NLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVP 192 + S +K L E+ + N + L + F+ +V + ++ ++ Sbjct: 79 QNDNIDHTRSYYKQLLESAQQDNKDYDLNIATNFFVDDFIEVINKYQQIANTHYHAMLEK 138 Query: 193 MNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLI-LVDYILFKGKWLTPFDPVFT 251 +++ N +Q +N+++++ T G++ ++ + E +I LV+ I FKG W PF V Sbjct: 139 VSYSNPTQTAATINNWVSEHTNGRLREIVTPDSLEGAVITLVNVIYFKGLWTYPFPEVAN 198 Query: 252 EVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATML-VVLMEKMGDHL 310 V F+ + K M G+F + +L+LPY+GN + +L Sbjct: 199 NVKPFYGTRGKPTNAQYMEQNGQFYYDNSADLGAQILRLPYRGNKLAMYFILPNPDNTVN 258 Query: 311 ALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSEL 370 + D + + + L M+ + V PKFK D +++E L+Q+GIR IFS A L L Sbjct: 259 QVLDRINSASLHQALWYMEENEVNVTLPKFKFDFSEQLNEPLQQVGIREIFSQNASLPLL 318 Query: 371 S---ATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEIT---AYSMPPVIKVDRPFHFMI 424 + ++VSR+ Q+ I ++E G+EA A ++ + +RPF F I Sbjct: 319 ARGRGARDEVRVSRIFQKAGITINELGSEAYAATEIQLVNKFGGDGVQIFNANRPFIFFI 378 Query: 425 YEETSGMLLFLGRVVNPTL 443 +ET G +LF G++ NP Sbjct: 379 EDETLGTMLFAGKIENPVF 397 >5NCU-A nrPDB Length = 336 Score = 311 bits (798), Expect = 3e-85, Method: Composition-based stats. Identities = 81/338 (23%), Positives = 153/338 (45%), Gaps = 13/338 (3%) Query: 73 QQLAKETSNFGFSLLRKISMR-HDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQ 131 +++ K+ + F F LL+ + N+ SP +S+A+ + GA G T ++K L Sbjct: 6 EKIEKDNA-FAFDLLQTTRKHVTEANVFISPLSVSMALNMTLNGAAGVTADEMKTALR-- 62 Query: 132 ALKPTKPGLLPSLFKGLRE-TLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTEC 190 + LRE L + + + + + VKE F ++ ++D E Sbjct: 63 -ETGYTMEDINEYSHSLREALLKVDPSTTIGMANSIWYKQGELVKEPFILANRTHYDAEV 121 Query: 191 VPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVF 250 ++F + + +N + ++T KI K+ D I + L++ + FKG W+T F Sbjct: 122 KAVDFSSPATLPA-INGWCAQKTNDKITKILDYIPGNAFMYLINAVYFKGIWVTQFKKSD 180 Query: 251 TEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHL 310 T+ F T +V MM F T D+ C L++ Y A ++V++ G Sbjct: 181 TKRAPFRKADGTTQEVNMMAQKSTFGYTTDEC--CQYLEMDYGNKAFSMIVMLPNEGQTT 238 Query: 311 A-LEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEM-HELLRQMGIRRIFSPFADLS 368 + + L ++ ++ + + P+FK + KY + ++L +MG+ F+ AD Sbjct: 239 RDVIEQLDNKHWSMIIKGIRPTQVSLRMPRFKTECKYGLEKKILPEMGMNVPFTETADFP 298 Query: 369 ELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEIT 406 ++ + +SRV+ +T ++VDE GTEA A E+ Sbjct: 299 GITDAA--IFISRVIHKTFVQVDEEGTEAAAVTAVEMV 334 >2WXX-A nrPDB Length = 453 Score = 304 bits (780), Expect = 4e-83, Method: Composition-based stats. Identities = 101/443 (22%), Positives = 179/443 (40%), Gaps = 38/443 (8%) Query: 20 PGLAPSPQSPETPAP-QNQTSRVVQAPKEEEEDEQEASEEKASEEEKAWLMASRQQLAKE 78 P + P+S P P Q +TS V + + D+ + EK +E++ Q+A Sbjct: 24 PSVETLPESTFEPVPIQAKTSPVNE---KTLHDQLVLAAEKLEDEDRK----RAAQVAMI 76 Query: 79 TSNFGFSLLRKISMRHDG--NMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPT 136 T+ GF + + ++ G + SP + + LG+ PT +Q++ L + P Sbjct: 77 TNFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDV----PV 132 Query: 137 KPGLLPSLFKGLRETLSRNLELGL---------------TQGSFAFIHKDFDVKETFFNL 181 K G S G + + GL + F F +K +F Sbjct: 133 KEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIVVGLFTAPGFRLKHSFVQS 192 Query: 182 SKRYFDTECVPMNF---RNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILF 238 F P + + A +N +I T K+ + ++ ++ L+ Y+ F Sbjct: 193 LA-LFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTDSTLLFNTYVHF 251 Query: 239 KGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATM 298 +G + F V F +D ++ VPM+ G G F D V +P AT+ Sbjct: 252 QGT-MRGFS-QLPGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLGERATL 309 Query: 299 LVVLMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIR 358 L++ + D +E + + + TW+ N R + + P+ ++ Y + +LL + + Sbjct: 310 LLIQPHCISDLDRVEALIFQNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLP 369 Query: 359 RIFSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDR 418 + A+L+ + T N +V VL ++E+ G E + + + Sbjct: 370 TLLGAEANLNNIGDT--NPRVGEVLNSILLELK-AGEEEQPTTSVQQPGSPEALDVTLSS 426 Query: 419 PFHFMIYEETSGMLLFLGRVVNP 441 PF F IYE+ SG L FLGRV NP Sbjct: 427 PFLFAIYEQDSGTLHFLGRVNNP 449 >2WXZ-C nrPDB Length = 453 Score = 300 bits (768), Expect = 9e-82, Method: Composition-based stats. Identities = 101/447 (22%), Positives = 179/447 (40%), Gaps = 46/447 (10%) Query: 20 PGLAPSPQSPETPAP-QNQTSRVVQAPKEEEEDEQEASEEKASEEEKAWLMASRQQLAKE 78 P + P+ P P Q +TS V + + D+ + EK E++ Q+A Sbjct: 24 PSVETLPEPTFEPVPIQAKTSPVDE---KTLRDKLVLATEKLEAEDR----QRAAQVAMI 76 Query: 79 TSNFGFSLLRKISMRHD--GNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPT 136 + GF + + +S V SP + + LG+ PT +Q++ L + P Sbjct: 77 ANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGV----PV 132 Query: 137 KPGLLPSLFKGLRETLSRNLELGL---------------TQGSFAFIHKDFDVKETFFNL 181 K G S G + + GL + F +K+ F Sbjct: 133 KEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVES 192 Query: 182 SKRYFDTECVPMNF---RNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILF 238 F P + + A + +N ++ T K+ + ++ ++ L Y+ F Sbjct: 193 LG-PFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFNTYVHF 251 Query: 239 KGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATM 298 +GK + F T + F +D ++ VPM+ G G F D V ++P + T+ Sbjct: 252 QGK-MRGFS-QLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLGESVTL 309 Query: 299 LVVLMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIR 358 L++ + D +E + TW++N R + + P+ ++ Y + +LL Q + Sbjct: 310 LLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLS 369 Query: 359 RIFSPFADLSELSATGRNLQVSRVLQRTVIEV----DERGTEAVAGILSEITAYSMPPVI 414 + A+L ++ T N +V VL ++E+ +E+ TE+ S + Sbjct: 370 TLLGAEANLGKMGDT--NPRVGEVLNSILLELQAGEEEQPTESAQQPGSPEVL-----DV 422 Query: 415 KVDRPFHFMIYEETSGMLLFLGRVVNP 441 + PF F IYE SG L FLGRV NP Sbjct: 423 TLSSPFLFAIYERDSGALHFLGRVDNP 449 >3STO-A nrPDB Length = 406 Score = 299 bits (765), Expect = 2e-81, Method: Composition-based stats. Identities = 91/406 (22%), Positives = 177/406 (43%), Gaps = 29/406 (7%) Query: 60 ASEEEKAWLMASRQQLAKETSNFGFSLLRKISMRHDG-NMVFSPFGMSLAMTGL--MLGA 116 E + + S + F + L ++ G N + P G+ + L GA Sbjct: 6 TPENDDPYANISSHK------AFTHAYLSTVTADFGGDNFLTCPLGILFTLGILLGSGGA 59 Query: 117 TGPTETQIKRGLHLQALKP-----TKPGLLPSLFKGLRETL-------SRNLELGLTQGS 164 G T QI + + L++ + SL++ L +L + E + + Sbjct: 60 QGRTGYQIGKTMRLKSTSSSWNSSEAQQEMKSLYQELNNSLTSEKTFLNEKEENVVRIST 119 Query: 165 FAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLF-DE 223 F+ K ++V+ F + E ++F N + A +N ++++++ G + K F D+ Sbjct: 120 GIFVEKTYEVERRFNESIANDSEGELKQVDFSNRTSATVDINDWVDQQSNGLLEKFFTDD 179 Query: 224 INPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNF 283 I +T +ILV+ F+ W +PF+P +T + F++ + I V MM G ++ Sbjct: 180 IPDDTAMILVNVFYFRDFWQSPFEPHYTRKEDFYISPDRQITVDMMTQEGVMKYGKFEDE 239 Query: 284 RCHVLKLPYQGNATMLVVLME--KMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFK 341 ++ P V+++ K + A E ++ +++N+K + + PKF Sbjct: 240 GFEIVSKPLNNTRFTFVIVLPLEKWSLNGATELLNGNKVLSEYVKNLKETTVSLRLPKFT 299 Query: 342 LDQKYEMHELLRQMGIRRIFSP-FADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAG 400 L ++ L+ +G+ +F P +DLS ++ NL V+ +Q V++++E G EA Sbjct: 300 LKNTLDLVPTLKSIGVVDLFDPVKSDLSGITP-NPNLYVNEFIQTNVLKLNESGIEATTV 358 Query: 401 ILSEITAYS--MPPV-IKVDRPFHFMIYEETSGMLLFLGRVVNPTL 443 +S +P V V PF IY++ M + +V+NP L Sbjct: 359 TSPIFVPFSAIIPEVDFHVTHPFICFIYDQQLTMPIMAAKVMNPVL 404 >3LE2-A nrPDB Length = 393 Score = 298 bits (763), Expect = 3e-81, Method: Composition-based stats. Identities = 94/386 (24%), Positives = 165/386 (42%), Gaps = 25/386 (6%) Query: 77 KETSNFGFSLLRKI--SMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALK 134 + +L + + ++ + N++FSP +++ ++ + G+ G T+ QI L + Sbjct: 10 SLQNQVSMNLAKHVITTVSQNSNVIFSPASINVVLSIIAAGSAGATKDQILSFLKFSS-T 68 Query: 135 PTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMN 194 + + S N L+ + A+I K K +F L + + + Sbjct: 69 DQLNSFSSEIVSAVLADGSANGGPKLSVANGAWIDKSLSFKPSFKQLLEDSYKAASNQAD 128 Query: 195 F-RNASQAKRLMNHYINKETRGKIPKLFDE--INPETKLILVDYILFKGKWLTPFDPVFT 251 F A + +N + KET G I ++ E + TKLI + + FKG W FD T Sbjct: 129 FQSKAVEVIAEVNSWAEKETNGLITEVLPEGSADSMTKLIFANALYFKGTWNEKFDESLT 188 Query: 252 EVDTFHLDKYKTIKVPMM-YGAGKFASTFDKNFRCHVLKLPY-----QGNATMLVVLMEK 305 + FHL + P M ++ S +D VL LPY + +M L + Sbjct: 189 QEGEFHLLDGNKVTAPFMTSKKKQYVSAYD---GFKVLGLPYLQGQDKRQFSMYFYLPDA 245 Query: 306 MGDHLALEDYL--TTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSP 363 L D + T ++ + + + E PKFK ++ +L+ +G+ FS Sbjct: 246 NNGLSDLLDKIVSTPGFLDNHIPRRQVKVREFKIPKFKFSFGFDASNVLKGLGLTSPFSG 305 Query: 364 FADLSELSAT---GRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSM-----PPVIK 415 L+E+ + G+NL VS + + IEV+E GTEA A I + Sbjct: 306 EEGLTEMVESPEMGKNLCVSNIFHKACIEVNEEGTEAAAASAGVIKLRGLLMEEDEIDFV 365 Query: 416 VDRPFHFMIYEETSGMLLFLGRVVNP 441 D PF ++ E +G++LF+G+VV+P Sbjct: 366 ADHPFLLVVTENITGVVLFIGQVVDP 391 >2PEF-A nrPDB Length = 373 Score = 297 bits (760), Expect = 8e-81, Method: Composition-based stats. Identities = 92/375 (24%), Positives = 159/375 (42%), Gaps = 17/375 (4%) Query: 73 QQLAKETSNFGFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQA 132 ++ T++F L + S+ N + SP LA+ GA T Q+++ L Sbjct: 7 EKFIYNTADFSIELFKN-SIDDKENSLISPLSAMLALAMTANGADNETLAQMEKALGKDI 65 Query: 133 LKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFA-FIHKDFDVKETFFNLSKRYFDTECV 191 L + K L LT + F DF + F + Y+ + Sbjct: 66 SIEDLNKYLYTYMKKLPNEEKSK----LTIANSIWFKENDFMPSKDFLQIIADYYKADIF 121 Query: 192 PMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFT 251 F +++ + +N+++ +T G I K+ ++I+PE + L++ + F +W T ++ Sbjct: 122 KAAFDSSTVS--DINNWVKSKTNGMIDKILNKIDPEDVMYLINAVAFDAEWETVYEKASV 179 Query: 252 EVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLV-VLMEKMGDHL 310 D F KV M + + PY N V +L ++ Sbjct: 180 HEDIFTDVYGNRQKVEFMNSEENL---YIEEENAVGFVKPYAKNHYSFVAILPDENISVN 236 Query: 311 ALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSP-FADLSE 369 LT ++N K + PKFK + +M+E L +G+ F P AD S+ Sbjct: 237 EYIKTLTGQKFIDLIKNAKITLVRASLPKFKYEYTIKMNETLESLGMTDAFLPDKADFSK 296 Query: 370 LSATG-RNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVI---KVDRPFHFMIY 425 L + NL +S VL +T I VDE GT+A A +ITA +P K++RPF F I Sbjct: 297 LGKSDIGNLYISEVLHKTFISVDELGTKAGAVTSVDITAAGIPVNFKTVKLNRPFIFAII 356 Query: 426 EETSGMLLFLGRVVN 440 + ++ + +F+G V++ Sbjct: 357 DNSTNLPIFIGTVLS 371 >1C8O-A nrPDB Length = 300 Score = 286 bits (731), Expect = 2e-77, Method: Composition-based stats. Identities = 82/325 (25%), Positives = 147/325 (45%), Gaps = 31/325 (9%) Query: 84 FSLLRKISMRHDG-NMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLP 142 + R+I+ G N+ SP +S +T L GA G T Q+ + + +A K Sbjct: 1 MDIFREIASSMKGENVFISPPSISSVLTILYYGANGSTAEQLSKYVEKEADKNKDDISFK 60 Query: 143 SLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAK 202 S+ + + K++F F T ++F ++ Sbjct: 61 SM-------------------NKVYGRYSAVFKDSFLRKIGDNFQT----VDFTDSRTV- 96 Query: 203 RLMNHYINKETRGKIPKLFDE-INPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKY 261 +N ++ T GKI L DE ++P+T L+ + + FK KWL PF+ FT F++ Sbjct: 97 DAINKSVDIFTEGKINPLLDEPLSPDTSLLAISAVYFKAKWLMPFEKEFTSDYPFYVSPT 156 Query: 262 KTIKVPMMYGAGK-FASTFDKN--FRCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLTT 318 + + V MM G+ F K +++LPY G+ +M+V+L + + ++E LT Sbjct: 157 EMVDVSMMSMYGEAFNHASVKESFGNFSIIELPYVGDTSMVVILPDNIDGLESIEQNLTD 216 Query: 319 DLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQ 378 + W +M ++V PKFK+ Y + + L ++G+ +F D S +S ++ Sbjct: 217 TNFKKWSDSMDAMFIDVHIPKFKVTGSYNLVDALVKLGLTEVFGSTGDYSNMS--NSDVS 274 Query: 379 VSRVLQRTVIEVDERGTEAVAGILS 403 V ++ +T I+V+E TEA A + Sbjct: 275 VDAMIHKTYIDVNEEYTEAAAATSA 299 >2OAY-A nrPDB Length = 390 Score = 278 bits (712), Expect = 2e-75, Method: Composition-based stats. Identities = 95/380 (25%), Positives = 177/380 (46%), Gaps = 24/380 (6%) Query: 69 MASRQQLAKETSNFGFSLLRKIS--MRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKR 126 ++ L +F L S + + NM FSPF ++ +T ++LGA T+T ++ Sbjct: 26 HSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLES 85 Query: 127 GLHLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYF 186 L P F + + L G+T S F D +++TF N S+ + Sbjct: 86 ILSY-----------PKDFTCVHQALKGFTTKGVTSVSQIFHSPDLAIRDTFVNASRTLY 134 Query: 187 DTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPF 246 + ++ N+ L+N ++ K T KI +L D + +T+L+L++ I KW T F Sbjct: 135 SSSPRVLS-NNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKTTF 193 Query: 247 DPVFTEVDTFHLDKYKTIKVPMMYGAGK-FASTFDKNFRCHVLKLPYQGNATMLVVLMEK 305 DP T ++ FH K IKVPMM A D+ + V +L N ++++++ + Sbjct: 194 DPKKTRMEPFHF-KNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVPQN 252 Query: 306 MGD-HLALEDYLTTDLVETWLRNMKTRNME---VFFPKFKLDQKYEMHELLRQMGIRRIF 361 + +E L+ + + + ++ + + P+ K+ +M ++ ++ F Sbjct: 253 LKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFD-F 311 Query: 362 SPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFH 421 S +L L+ +LQVS + +TV+E+ E G EA A + + V +V +PF Sbjct: 312 SYDLNLCGLTE-DPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLL--VFEVQQPFL 368 Query: 422 FMIYEETSGMLLFLGRVVNP 441 FM++++ +F+GRV +P Sbjct: 369 FMLWDQQHKFPVFMGRVYDP 388 >1JJO-C nrPDB Length = 261 Score = 274 bits (700), Expect = 7e-74, Method: Composition-based stats. Identities = 67/261 (25%), Positives = 128/261 (49%), Gaps = 10/261 (3%) Query: 156 LELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINKETRG 215 + + + F+ F V E F + K YF+ E ++F +N ++ T Sbjct: 2 NQYVMKLANSLFVQNGFHVNEEFLQMLKMYFNAEVNHVDFSQNVAVANSINKWVENYTNS 61 Query: 216 KIPKLFD--EINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAG 273 + L + + T L L++ + FKG W + F P T +F D +++PMMY G Sbjct: 62 LLKDLVSPEDFDGVTNLALINAVYFKGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQQG 121 Query: 274 KFAST------FDKNFRCHVLKLPYQGNA-TMLVVLMEKMGDHLALEDYLTTDLVETWLR 326 +F + VL++PY+G+ +M++ L + LE L L+E W Sbjct: 122 EFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLALSRQEVPLATLEPLLKAQLIEEWAN 181 Query: 327 NMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSRVLQRT 386 ++K + +EV+ P+F ++Q+ ++ ++L+ +G+ IF A+L+ +S + L +S+ + ++ Sbjct: 182 SVKKQKVEVYLPRFTVEQEIDLKDILKALGVTEIFIKDANLTAMSD-KKELFLSKAVHKS 240 Query: 387 VIEVDERGTEAVAGILSEITA 407 IEV+E G+EA A + Sbjct: 241 CIEVNEEGSEAAAASGMIAIS 261 >1SNG-A nrPDB Length = 370 Score = 266 bits (679), Expect = 2e-71, Method: Composition-based stats. Identities = 93/370 (25%), Positives = 164/370 (44%), Gaps = 31/370 (8%) Query: 81 NFGFSLLRKISMR-HDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPG 139 F L R+++ DG +++SP+ ++ A+ L GA R L Sbjct: 16 EFALHLHRRLAEAVPDGEVIWSPYSVACALGVLAAGARAT-----TRTELTTLLGTDPAP 70 Query: 140 LLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFR-NA 198 LL +L + + ++ L + ++ D V+ +F D++ +FR N Sbjct: 71 LLAALDRAVTDSPD------LASRTVLWVSADVPVRSSFRATMHDRPDSDVRTADFRTNP 124 Query: 199 SQAKRLMNHYINKETRGKIPKLFDE--INPETKLILVDYILFKGKWLTPFDPVFTEVDTF 256 + +N I TRG I +L + + P+ + IL + + K +W TPF+ T TF Sbjct: 125 EGVRATVNADIADATRGMIRELLPQGAVTPDLRAILTNALWAKARWTTPFEAHLTRAGTF 184 Query: 257 HLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLALEDYL 316 + +VP M+ + +R L + + + VL+ + A+ Sbjct: 185 RTPRGP-KRVPFMHRTKTMPYATARGWRMVTL---HAHDELAVDVLLPPGTNAAAVP--- 237 Query: 317 TTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRN 376 T L+ R + ++E+ P+F+L Q +++ E+L + G+R +F+ ADLS +S Sbjct: 238 TAPLLTALHRRSASTSVELALPRFELTQPHQLVEVLAEAGVRTLFTASADLSGISTV--P 295 Query: 377 LQVSRVLQRTVIEVDERGTEAVAGILSEITAYS-MPP----VIKVDRPFHFMIYEETSGM 431 L V V+ + + VDERG E A + + MPP VDRPFH ++ G Sbjct: 296 LYVDTVIHQARLRVDERGAEGAAATAAMMLLAGAMPPRRTIRFSVDRPFHIVVRRR--GA 353 Query: 432 LLFLGRVVNP 441 +LFLG + +P Sbjct: 354 ILFLGSIADP 363 >5M3Y-A nrPDB Length = 458 Score = 263 bits (673), Expect = 8e-71, Method: Composition-based stats. Identities = 90/440 (20%), Positives = 170/440 (38%), Gaps = 41/440 (9%) Query: 20 PGLAPSPQSPETPAPQNQTSRVVQAPKEEEEDEQEASEEKASEEEKAWLMASRQQLAKET 79 P P+P +T + +D+ K E+K + Sbjct: 32 PTFIPAPIQAKTSPVDEKAL----------QDQLVLVAAKLDTEDKL----RAAMVGMLA 77 Query: 80 SNFGFSLL---RKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQ----- 131 + GF + ++ G V SP + + L LGA T +++ L + Sbjct: 78 NFLGFRIYGMHSELWGVVHGATVLSPTAVFGTLASLYLGALDHTADRLQAILGVPWKDKQ 137 Query: 132 -ALKPTKPGLLPSLF--KGLRETLSR---NLELGLTQGSFAFIHKDFDVKETFFNLSKRY 185 + +L +L +GL R +L L+ F +K+ F Sbjct: 138 CTSRLDAHKVLSALQAVQGLLVAQGRADSQAQLLLSTVVGVFTAPGLHLKQPFVQGLA-L 196 Query: 186 FDTECVP--MNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWL 243 + +P ++F A ++ ++ T K + ++ L Y+ F+GK + Sbjct: 197 YTPVVLPRSLDFTELDVAAEKIDRFMQAVTGWKTGSSLMGASVDSTLAFNTYVHFQGK-M 255 Query: 244 TPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLM 303 F + E F +D+ ++ VPM+ G G F D + V ++P+ +A++L++ Sbjct: 256 KGFS-LLAEPQEFWVDQSTSVSVPMLSGMGTFQHWSDIQDQFSVTQVPFTESASLLLIQP 314 Query: 304 EKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSP 363 D +E W++ + R + + P+ L Y++ +LL Q + I Sbjct: 315 HYASDLDKVEGLTFQQNSLNWMKKLSPRTIHLTMPQLVLQGSYDLQDLLAQAELPAILHT 374 Query: 364 FADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKV--DRPFH 421 +L +LS ++V VL E++ E + P V++V +RPF Sbjct: 375 ELNLQKLS--NDRIRVGEVLNSIFFELEADEREPTEST----QQLNKPEVLEVTLNRPFL 428 Query: 422 FMIYEETSGMLLFLGRVVNP 441 F +Y++++ L FLGRV NP Sbjct: 429 FAVYDQSATALHFLGRVANP 448 >5C98-A nrPDB Length = 382 Score = 249 bits (637), Expect = 1e-66, Method: Composition-based stats. Identities = 70/380 (18%), Positives = 137/380 (36%), Gaps = 30/380 (7%) Query: 71 SRQQLAKETSNFGFSLLRKISMRHDGNMVFSPFGMSLAMTGLM--LGATGPTETQIKRGL 128 + + + F + N SP+ + LA++ GA + Q+ GL Sbjct: 13 TDDAIVAANNKFTLEYFKACY-DEKCNCAVSPYHVRLALSMFYPLAGAAVQEDFQVAFGL 71 Query: 129 HLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDT 188 + ++ + R + L SF + + + F L R F T Sbjct: 72 --------PEDVHAAIEQQQRLAQQLHDGQHLKALSFVLVEETLRLDSEFERLFHRTFQT 123 Query: 189 ECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDE-----INPETKLILVDYILFKGKWL 243 P++ + + +N + + +I E + P KL+L + Sbjct: 124 TVEPVDLTDDIPSALAVNSFYQRA-NTEIEDFIGEGDVFSLPPCHKLMLFSGVSVLTPLA 182 Query: 244 TPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPY--QGNATMLVV 301 F+P T ++ F T +V M+ RC V+ +P+ +MLV+ Sbjct: 183 IRFNPADTALELFQFINAPTQRVSTMHTTAFVRRCLHNELRCKVVDMPFDAASGLSMLVL 242 Query: 302 LMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIF 361 L + + + +T + +++ ++ PKF + +K + + L ++G +F Sbjct: 243 LPYDGTELRQIVNSITPAHLAQIDERLQSCWTDLKLPKFFVREKTDPKQTLGKLGYGGVF 302 Query: 362 SPFADLSELSATGRNLQVSRVLQRTVIEVDERGT--EAVAGILSEITAYSMPPVIKVDRP 419 DL +GR +++ +Q + V E G+ A SE +RP Sbjct: 303 E-IDDLHVFHDSGRT-RLNGFIQHCYLAVSESGSGIPAPPDTPSEF-------EFHANRP 353 Query: 420 FHFMIYEETSGMLLFLGRVV 439 F F+I G +L +G Sbjct: 354 FMFLIRRTMDGNVLQVGNFS 373 >6BJ5-B nrPDB Length = 315 Score = 246 bits (627), Expect = 2e-65, Method: Composition-based stats. Identities = 91/328 (27%), Positives = 152/328 (46%), Gaps = 35/328 (10%) Query: 81 NFGFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGL 140 + G R + D N+VFSP+G++ A++ L + A G T+ +I P Sbjct: 17 DIGLWTFRYVYNESD-NVVFSPYGLTSALSVLRIAAGGNTKREI--------DVPESVVE 67 Query: 141 LPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQ 200 F LRE F+ ++ F F+T + F N+ Sbjct: 68 DSDAFLALRE---------------LFVDASVPLRPEFTAEFSSRFNTSVQRVTF-NSEN 111 Query: 201 AKRLMNHYINKETRGKIPKLFD-EINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLD 259 K ++N Y+ +T G +P++ D ++ +TK++L+ + K W FDP FT F+ Sbjct: 112 VKDVINSYVKDKTGGDVPRVLDASLDRDTKMLLLSSVRMKTSWRHVFDPSFTTDQPFY-S 170 Query: 260 KYKTIKVPMMYGAGKFAS--TFDKNFRCHVLKLPYQGNAT-MLVVLMEKMGDHLALEDYL 316 T KV MM + +N V +LPY+ T ML+V+ + +G+ + L Sbjct: 171 GNVTYKVRMMNKIDTLKTETFTLRNVGYSVTELPYKRRQTAMLLVVPDDLGEIVR---AL 227 Query: 317 TTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPF-ADLSELSATGR 375 LV W+RNM+ +V PKF ++ ++ + L+++G+R F P AD + S + Sbjct: 228 DLSLVRFWIRNMRKDVCQVVMPKFSVESVLDLRDALQRLGVRDAFDPSRADFGQASPSN- 286 Query: 376 NLQVSRVLQRTVIEVDERGTEAVAGILS 403 +L V++VLQ + IE DERGT A + Sbjct: 287 DLYVTKVLQTSKIEADERGTTASSDTAI 314 >1M93-B nrPDB Length = 245 Score = 244 bits (624), Expect = 5e-65, Method: Composition-based stats. Identities = 65/251 (25%), Positives = 121/251 (48%), Gaps = 11/251 (4%) Query: 157 ELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGK 216 ++ + + K++F F T ++F ++ +N ++ T GK Sbjct: 1 DISFKSMNKVYGRYSAVFKDSFLRKIGDNFQT----VDFTDSRTV-DAINKSVDIFTEGK 55 Query: 217 IPKLFDE-INPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGK- 274 I L DE ++P+T L+ + + FK KWL PF+ FT F++ + + V MM G+ Sbjct: 56 INPLLDEPLSPDTSLLAISAVYFKAKWLMPFEKEFTSDYPFYVSPTEMVDVSMMSMYGEA 115 Query: 275 FASTFDKN--FRCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLTTDLVETWLRNMKTRN 332 F K +++LPY G+ +M+V+L + + ++E LT + W +M Sbjct: 116 FNHASVKESFGNFSIIELPYVGDTSMVVILPDNIDGLESIEQNLTDTNFKKWSDSMDAMF 175 Query: 333 MEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSRVLQRTVIEVDE 392 ++V PKFK+ Y + + L ++G+ +F D S +S ++ V ++ +T I+V+E Sbjct: 176 IDVHIPKFKVTGSYNLVDALVKLGLTEVFGSTGDYSNMS--NSDVSVDAMIHKTYIDVNE 233 Query: 393 RGTEAVAGILS 403 TEA A + Sbjct: 234 EYTEAAAATSA 244 >1MTP-A nrPDB Length = 323 Score = 240 bits (613), Expect = 8e-64, Method: Composition-based stats. Identities = 75/317 (23%), Positives = 139/317 (43%), Gaps = 24/317 (7%) Query: 81 NFGFSLLRKISMR-HDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPG 139 F L R+++ DG +++SP+ ++ A+ L GA R L Sbjct: 12 EFALHLHRRLAEAVPDGEVIWSPYSVACALGVLAAGARAT-----TRTELTTLLGTDPAP 66 Query: 140 LLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFR-NA 198 LL +L + + ++ L + ++ D V+ +F D++ +FR N Sbjct: 67 LLAALDRAVTDSPD------LASRTVLWVSADVPVRSSFRATMHDRPDSDVRTADFRTNP 120 Query: 199 SQAKRLMNHYINKETRGKIPKLFDE--INPETKLILVDYILFKGKWLTPFDPVFTEVDTF 256 + +N I TRG I +L + + P+ + IL + + K +W TPF+ T TF Sbjct: 121 EGVRATVNADIADATRGMIRELLPQGAVTPDLRAILTNALWAKARWTTPFEAHLTREGTF 180 Query: 257 HLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLALEDYL 316 + +VP M+ + +R L + + + VL+ + A+ Sbjct: 181 RTPRGP-KRVPFMHRTKTMPYATARGWRMVTL---HAHDELAVDVLLPPGTNAAAVP--- 233 Query: 317 TTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRN 376 T L+ R + ++E+ P+F+L Q +++ E+L + G+R +F+ ADLS +S Sbjct: 234 TAPLLTALHRRSASTSVELALPRFELTQPHQLVEVLAEAGVRTLFTASADLSGISTV--P 291 Query: 377 LQVSRVLQRTVIEVDER 393 L V V+ + + VDER Sbjct: 292 LYVDTVIHQARLRVDER 308 >4R9I-A nrPDB Length = 378 Score = 93.5 bits (231), Expect = 2e-19, Method: Composition-based stats. Identities = 57/358 (15%), Positives = 129/358 (36%), Gaps = 25/358 (6%) Query: 93 RHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRETL 152 + N + F + ++ L L + T ++ + L+L+ + ++ + + L Sbjct: 36 EPERNQFSTAFPLLFMLSELSLNSKEDTTAELYKNLNLR-----SEDEVVNVNQAVNTNL 90 Query: 153 S-RNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINK 211 + +N T A+ D ETF + F+ +++ N A + + Sbjct: 91 NTKNEVYQSTLILNAYTDIDSPFSETFIQNFAKVFNGTVKNIDYSN--DAVATIRDSLQS 148 Query: 212 ETRGKIPKLFD--EINPETKLILVDY--ILFK-GKWLTPFDPVFTEVDTFHLDKYKTIKV 266 ++ I +IN +T +IL Y I F G+ + P +F Sbjct: 149 DSGNDIEIALKDGDINKDTGIILTAYTNIYFPWGEASDSYRPYKQIDISFTALDGTQSNK 208 Query: 267 PMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLV--VLMEKMGDHLALEDYLTTDLVETW 324 Y G +N V + + T+++ L + A + Sbjct: 209 QAWYSEGAGKYAEIENLGIKVFQFSLKPGLTVVLGTSLNDNNDLSGAFNKLRDPATLAYI 268 Query: 325 LRNMKTRNMEVFFP-KFKLDQKYEMHELLRQMG-IRRIFSPFADLSELSATGRNLQVSRV 382 L +++ +++ P + + + +++ G + +F D + ++ +S + Sbjct: 269 LTQTESKYLKLAVPIELTMRDSRDYIPEVKRAGLLTELFEKNFDGFDTVYDNKSGYISYM 328 Query: 383 LQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYEETSGMLLFLGRVVN 440 L T +E E+ TE A + P D+P+ F++ ++ F+G + N Sbjct: 329 LSHTRLEF-EQPTEEQAASVVAE------PDFIFDKPYFFLVLDQF-NTPAFIGLITN 378 >1O4S-A nrPDB Length = 389 Score = 33.8 bits (76), Expect = 0.15, Method: Composition-based stats. Identities = 32/214 (14%), Positives = 63/214 (29%), Gaps = 19/214 (8%) Query: 26 PQSPETPAPQNQTSRVVQAPKEEEEDEQEASE-----EKASEEEKAWLMASRQQLAKETS 80 P P + R +Q + + D + E K E ++ Q + + Sbjct: 51 PDFPTPEPVVEEAVRFLQKGEVKYTDPRGIYELREGIAKRIGERYKKDISPDQVVVTNGA 110 Query: 81 NFG-FSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPG 139 F+ + D +VFSP +S ++ G T + + Q G Sbjct: 111 KQALFNAFMALLDPGDEVIVFSPVWVSYIPQIILAGGTVN-VVETFMSKNFQPSLEEVEG 169 Query: 140 LLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDV--KETFFNLSKRYFDTECVPMNFRN 197 LL K + ++ F+ + K F+ +S +D+ F + Sbjct: 170 LLVGKTKAV--LINSPNNPTGVVYRREFLEGLVRLAKKRNFYIISDEVYDSLVYTDEFTS 227 Query: 198 ASQAKR------LMNHYINKE--TRGKIPKLFDE 223 +N + T ++ L Sbjct: 228 ILDVSEGFDRIVYINGFSKSHSMTGWRVGYLISS 261 >4PSX-A nrPDB Length = 320 Score = 31.5 bits (70), Expect = 0.79, Method: Composition-based stats. Identities = 24/115 (20%), Positives = 50/115 (43%), Gaps = 15/115 (13%) Query: 271 GAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLTTDLVETWLRNMKT 330 GA F DK FR + + L+ + H + L ++++WL + Sbjct: 201 GAKSFDEDIDKKFRAKISQF--------LIFPPYQNKGHGS---CLYEAIIQSWLEDKSI 249 Query: 331 RNMEVFFPKFKLDQKYEMHEL--LRQMGIRRIFSPFADLSE--LSATGRNLQVSR 381 + V P D + +++ LR++G +F +DLS+ L ++ ++L++ Sbjct: 250 TEITVEDPNEAFDDLRDRNDIQRLRKLGYDAVFQKHSDLSDEFLESSRKSLKLEE 304 >5W76-A nrPDB Length = 385 Score = 31.5 bits (70), Expect = 0.81, Method: Composition-based stats. Identities = 13/42 (30%), Positives = 22/42 (52%) Query: 388 IEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYEETS 429 +E DE G EA+ ++ + +Y P +D+PF I + S Sbjct: 171 LEGDEEGEEAIMKLMDAVDSYIPEPERAIDKPFLMPIEDVFS 212 >5U6P-A nrPDB Length = 660 Score = 31.1 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 11/78 (14%), Positives = 33/78 (42%), Gaps = 9/78 (11%) Query: 165 FAFIHKDFDVKETFFNLSKRYFDTECVPM----NFRN-ASQAKRLMNHYINKETRGKI-- 217 F+ + ++ + S+R + + + +F + ++ ++ Y +GKI Sbjct: 387 AMFVGHATALIQS-LDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQGKIFD 445 Query: 218 -PKLFDEINPETKLILVD 234 + +E+N + +V+ Sbjct: 446 EENILNELNDPLREEIVN 463 >6EEM-B nrPDB Length = 512 Score = 31.1 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 12/59 (20%), Positives = 23/59 (38%), Gaps = 1/59 (1%) Query: 206 NHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKTI 264 N YI +T KL + +N K+ + + G ++ F T + H+ + Sbjct: 444 NDYIEDQTNEVNVKLLESVNASGKIYMTHAV-VGGVYMIRFAVGATLTEERHVTGAWKV 501 >4P2L-A nrPDB Length = 506 Score = 30.7 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 13/66 (19%), Positives = 25/66 (37%), Gaps = 22/66 (33%) Query: 175 KETFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVD 234 + F + +YF + + NF ++ +N ++ K+ + KIP Sbjct: 290 LKKFVAVLAKYFPGQPLVQNFLHS------INDWLQKQQKKKIP---------------- 327 Query: 235 YILFKG 240 Y FK Sbjct: 328 YSYFKA 333 >4AXG-A nrPDB Length = 248 Score = 30.3 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 9/42 (21%), Positives = 15/42 (35%) Query: 21 GLAPSPQSPETPAPQNQTSRVVQAPKEEEEDEQEASEEKASE 62 APS + P + + + +ED QE E + Sbjct: 9 TSAPSTEQGRPEPPTSAAAPAEAKDVKPKEDPQETGEPAGNT 50 >6DS5-A nrPDB Length = 409 Score = 30.3 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 13/59 (22%), Positives = 28/59 (47%), Gaps = 3/59 (5%) Query: 23 APSPQSPETPAPQNQTSRVVQAPKEEEEDEQEASEEKASEEEKAWLMASRQQLAKETSN 81 P P+ E PQ+ + ++P++ E + SEE+ +++ ++L E S+ Sbjct: 303 QPGPEGQEESTPQSDVTEDGESPEDPSGTEGQLSEEEKPDQQPLSGE---EELEPEASD 358 >3H1Q-A nrPDB Length = 272 Score = 29.9 bits (66), Expect = 2.0, Method: Composition-based stats. Identities = 15/43 (34%), Positives = 18/43 (41%), Gaps = 4/43 (9%) Query: 214 RGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTEVDTF 256 +GKI FDE T L LV G + PF+ T F Sbjct: 158 KGKITATFDEPTGGTHLSLVLA----GSYKIPFEEAETIKKDF 196 >5I9J-A nrPDB Length = 229 Score = 29.2 bits (64), Expect = 3.7, Method: Composition-based stats. Identities = 8/60 (13%), Positives = 23/60 (38%) Query: 274 KFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLTTDLVETWLRNMKTRNM 333 KF + + +++P+ G +L + + + E L + + W + + + Sbjct: 45 KFEKNNEYGDTVYTIEVPFHGKTFILKTFLPCPAELVYQEVILQPERMVLWNKTVTACQI 104 >3T59-A nrPDB Length = 519 Score = 29.2 bits (64), Expect = 4.3, Method: Composition-based stats. Identities = 9/44 (20%), Positives = 22/44 (50%), Gaps = 6/44 (13%) Query: 175 KETFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIP 218 + F + +YF + + NF ++ +N ++ K+ + +IP Sbjct: 302 LKKFVAVLAKYFPGQPLVQNFLHS------INDWLQKQQKKRIP 339 >5CA8-A nrPDB Length = 692 Score = 28.8 bits (63), Expect = 4.5, Method: Composition-based stats. Identities = 19/162 (11%), Positives = 44/162 (27%), Gaps = 35/162 (21%) Query: 173 DVKETFFNLSKRYFD---------------TECVPMNFRNASQAKRLMNHYI----NKET 213 V + F + +F + F + + N + K+ Sbjct: 330 SVFQEFLTKYQHHFKEVDAAPDFEELGALFADLRQDAFEDYDASASRYNKAVYEQKRKKL 389 Query: 214 RGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAG 273 R I E+ L + + L F+ + K + V + Sbjct: 390 RWLINDKLKEVFDVHAKNLCNTL------LEKFEKDLVAL----KGKDFAVNVKTLSTK- 438 Query: 274 KFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLALEDY 315 ++ V + QG+ ++ +++ D A+ Sbjct: 439 -----LVEDVNFQVSLMSLQGDLSLDEIILALTKDIDAIVAK 475 >1W1W-A nrPDB Length = 430 Score = 28.4 bits (62), Expect = 6.7, Method: Composition-based stats. Identities = 17/83 (20%), Positives = 32/83 (38%), Gaps = 7/83 (8%) Query: 20 PGLAPSPQSPETPAPQNQTSRVVQAPKEEEEDEQEASEEKASEEEKAWLMASRQQLAKET 79 PGL Q P R E EQ +EEK + + R++L ++T Sbjct: 216 PGLEVLFQGPRGSRYDEAEGRFEVINNE---TEQLKAEEKKILNQFLKIKKKRKELFEKT 272 Query: 80 SNFGFS----LLRKISMRHDGNM 98 ++ + R+++ + N+ Sbjct: 273 FDYVSDHLDAIYRELTKNPNSNV 295 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.142 0.398 Lambda K H 0.267 0.0438 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,414,973 Number of Sequences: 36641 Number of extensions: 711649 Number of successful extensions: 3068 Number of sequences better than 10.0: 78 Number of HSP's better than 10.0 without gapping: 131 Number of HSP's successfully gapped in prelim test: 22 Number of HSP's that attempted gapping in prelim test: 2366 Number of HSP's gapped (non-prelim): 191 length of query: 444 length of database: 10,336,785 effective HSP length: 100 effective length of query: 344 effective length of database: 6,672,685 effective search space: 2295403640 effective search space used: 2295403640 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.0 bits) S2: 61 (28.0 bits)