BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9UJX3 (599 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5G04-X nrPDB 1237 0.0 5G04-F nrPDB 61 1e-09 1W3B-A nrPDB 42 8e-04 5G05-C nrPDB 41 0.001 5LVV-A nrPDB 39 0.005 5JJT-A nrPDB 39 0.009 5A01-A nrPDB 37 0.030 5FZQ-A nrPDB 34 0.19 5ZYQ-A nrPDB 33 0.29 5MGX-E nrPDB 33 0.29 6B85-J nrPDB 33 0.37 4I2W-A nrPDB 32 1.1 2Y4T-A nrPDB 31 1.3 4GFK-A nrPDB 29 4.5 4TKZ-A nrPDB 29 6.4 5GVE-A nrPDB 28 7.9 2GW1-A nrPDB 28 9.1 >5G04-X nrPDB Length = 599 Score = 1237 bits (3201), Expect = 0.0, Method: Compositional matrix adjust. Identities = 599/599 (100%), Positives = 599/599 (100%) Query: 1 MDPGDAAILESSLRILYRLFESVLPPLPAALQSRMNVIDHVRDMAAAGLHSNVRLLSSLL 60 MDPGDAAILESSLRILYRLFESVLPPLPAALQSRMNVIDHVRDMAAAGLHSNVRLLSSLL Sbjct: 1 MDPGDAAILESSLRILYRLFESVLPPLPAALQSRMNVIDHVRDMAAAGLHSNVRLLSSLL 60 Query: 61 LTMSNNNPELFSPPQKYQLLVYHADSLFHDKEYRNAVSKYTMALQQKKALSKTSKVRPST 120 LTMSNNNPELFSPPQKYQLLVYHADSLFHDKEYRNAVSKYTMALQQKKALSKTSKVRPST Sbjct: 61 LTMSNNNPELFSPPQKYQLLVYHADSLFHDKEYRNAVSKYTMALQQKKALSKTSKVRPST 120 Query: 121 GNSASTPQSQCLPSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQRTPKINMMLANLYK 180 GNSASTPQSQCLPSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQRTPKINMMLANLYK Sbjct: 121 GNSASTPQSQCLPSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQRTPKINMMLANLYK 180 Query: 181 KAGQERPSVTSYKEVLRQCPLALDAILGLLSLSVKGAEVASMTMNVIQTVPNLDWLSVWI 240 KAGQERPSVTSYKEVLRQCPLALDAILGLLSLSVKGAEVASMTMNVIQTVPNLDWLSVWI Sbjct: 181 KAGQERPSVTSYKEVLRQCPLALDAILGLLSLSVKGAEVASMTMNVIQTVPNLDWLSVWI 240 Query: 241 KAYAFVHTGDNSRAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQML 300 KAYAFVHTGDNSRAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQML Sbjct: 241 KAYAFVHTGDNSRAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQML 300 Query: 301 DPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALY 360 DPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALY Sbjct: 301 DPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALY 360 Query: 361 LGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLAS 420 LGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLAS Sbjct: 361 LGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLAS 420 Query: 421 NSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVV 480 NSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVV Sbjct: 421 NSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVV 480 Query: 481 KKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDP 540 KKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDP Sbjct: 481 KKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDP 540 Query: 541 NDQKSLEGMQKMEKEESPTDATQEEDVDDMEGSGEEGDLEGSDSEAAQWADQEQWFGMQ 599 NDQKSLEGMQKMEKEESPTDATQEEDVDDMEGSGEEGDLEGSDSEAAQWADQEQWFGMQ Sbjct: 541 NDQKSLEGMQKMEKEESPTDATQEEDVDDMEGSGEEGDLEGSDSEAAQWADQEQWFGMQ 599 >5G04-F nrPDB Length = 824 Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 72/323 (22%), Positives = 135/323 (41%), Gaps = 18/323 (5%) Query: 273 LLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLF 332 +L + YF + + F + + ++ Y ++GM++Y L + + L L Sbjct: 501 VLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLT 560 Query: 333 NISDQHAEPWVVSG-CHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQE 391 ++ E W +G C S + + A+ +AIQ++ N A L G + + Sbjct: 561 DMDKNSPEAWCAAGNCFSL-QREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDK 619 Query: 392 AIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVC 451 A+ FR AIR+ P + + GL Y A + + K L N Q+ LL + Sbjct: 620 ALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEM---HFQKALDINPQSSVLLCHIG 676 Query: 452 LEDPVTQ--EKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDG---IALLRNALANQ 506 + + EKA L+KA+ P +A +L +KY+ + L+ + + Sbjct: 677 VVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKE 736 Query: 507 SDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDP----NDQKSLEGMQKMEKEESPTDAT 562 S +++ ++G + + A+ +S A+ LDP N K + + +E P T Sbjct: 737 S--LVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEEPI--T 792 Query: 563 QEEDVDDMEGSGEEGDLEGSDSE 585 QEE + + S E + D++ Sbjct: 793 QEEQIMGTDESQESSMTDADDTQ 815 >1W3B-A nrPDB Length = 388 Score = 42.0 bits (97), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 55/208 (26%), Positives = 89/208 (42%), Gaps = 19/208 (9%) Query: 343 VVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRL 402 ++S H F +R R+ + AI+ N +A G + G++QEAI H+R A+RL Sbjct: 38 LLSSIH-FQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRL 96 Query: 403 APCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATV--CLEDPVTQEK 460 P +D Y L +A+ + E V A L N + + + L+ E+ Sbjct: 97 KPDFIDGYINLAAALVAAGDM-EGAVQA--YVSALQYNPDLYCVRSDLGNLLKALGRLEE 153 Query: 461 AKTLLDKALTQRPDYIKA-------VVKKAELLSREQKYEDGIALLRNALANQSDCVLHR 513 AK KA+ +P++ A + E+ +E + L N L D ++ Sbjct: 154 AKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFL----DAYIN- 208 Query: 514 ILGDFLVAVNEYQEAMDQYSIALSLDPN 541 LG+ L + A+ Y ALSL PN Sbjct: 209 -LGNVLKEARIFDRAVAAYLRALSLSPN 235 Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust. Identities = 68/296 (22%), Positives = 116/296 (39%), Gaps = 22/296 (7%) Query: 175 LANLYKKAGQERPSVTSYKEVLRQCPLALDAILGLLSLSVKGAEVASMT---MNVIQTVP 231 L N+YK+ GQ + ++ Y+ LR P +D + L + V ++ ++ +Q P Sbjct: 73 LGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNP 132 Query: 232 NLDW----LSVWIKAYAFVHTGDNSRAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDN 287 +L L +KA + + C L+ + +L ++ G+ Sbjct: 133 DLYCVRSDLGNLLKALGRLEE-------AKACYLKAIETQPNFAVAWSNLGCVFNAQGEI 185 Query: 288 KNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLG-CRLFNISDQHAEPWVVSG 346 ++ FE+A LDP + G +L +E R+ D R ++S HA VV G Sbjct: 186 WLAIHHFEKAVTLDPNFLDAYINLGNVL-KEARIFDRAVAAYLRALSLSPNHA---VVHG 241 Query: 347 ---CHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLA 403 C + A+ +AI+L + A AL+ G V EA + A+RL Sbjct: 242 NLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLC 301 Query: 404 PCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQE 459 P D L +I EA+ + + A + LA+V + QE Sbjct: 302 PTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQE 357 Score = 40.0 bits (92), Expect = 0.003, Method: Compositional matrix adjust. Identities = 65/271 (23%), Positives = 99/271 (36%), Gaps = 39/271 (14%) Query: 269 DNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLG 328 D +D +LA AGD + +V + A +P L G LL GRLE+ + Sbjct: 99 DFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAK--A 156 Query: 329 CRLFNISDQ--HAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRN- 385 C L I Q A W GC A++ KA+ L+ N + A + G L+ Sbjct: 157 CYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEA 216 Query: 386 ---------------------------------MGRVQEAIIHFREAIRLAPCRLDCYEG 412 G + AI +R AI L P D Y Sbjct: 217 RIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCN 276 Query: 413 LIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQR 472 L S+ EA N + +A +L LA + E +E + L KAL Sbjct: 277 LANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVR-LYRKALEVF 335 Query: 473 PDYIKAVVKKAELLSREQKYEDGIALLRNAL 503 P++ A A +L ++ K ++ + + A+ Sbjct: 336 PEFAAAHSNLASVLQQQGKLQEALMHYKEAI 366 >5G05-C nrPDB Length = 597 Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust. Identities = 51/202 (25%), Positives = 81/202 (40%), Gaps = 12/202 (5%) Query: 225 NVIQTVPNLDWLSV---WIKAYAFVHTGDNSRAISTICSLEKKSLLRD-----NVDLLGS 276 N+I L +LS+ W+K + H + I +L+K L D + ++ Sbjct: 211 NLITDKEMLKFLSLPDTWMKEFFLAHIYTELQLIEE--ALQKYQNLIDVGFSKSSYIVSQ 268 Query: 277 LADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISD 336 +A Y D ++ F + + DPY I+ MD + LL ++ L L I Sbjct: 269 IAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDK 328 Query: 337 QHAEPWVVSG-CHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIH 395 E V G +S S+ ALY +A++LN + A L G M AI Sbjct: 329 YRVETCCVIGNYYSLRSQHEKAALYF-QRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQA 387 Query: 396 FREAIRLAPCRLDCYEGLIECY 417 +R AI + + GL + Y Sbjct: 388 YRHAIEVNKRDYRAWYGLGQTY 409 >5LVV-A nrPDB Length = 749 Score = 39.3 bits (90), Expect = 0.005, Method: Compositional matrix adjust. Identities = 24/88 (27%), Positives = 44/88 (50%), Gaps = 13/88 (14%) Query: 358 ALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCY------- 410 A+ L KA+++ A + L+ G++QEA++H++EAIR++P D Y Sbjct: 49 AVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTL 108 Query: 411 ------EGLIECYLASNSIREAMVMANN 432 +G ++CY + I A A++ Sbjct: 109 KEMQDVQGALQCYTRAIQINPAFADAHS 136 Score = 35.8 bits (81), Expect = 0.059, Method: Compositional matrix adjust. Identities = 34/147 (23%), Positives = 62/147 (42%) Query: 270 NVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGC 329 + D L +LA++ G+ + +V + +A + P +L ++G+L++ Sbjct: 29 HADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYK 88 Query: 330 RLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRV 389 IS A+ + G + AL +AIQ+N A + ++ G + Sbjct: 89 EAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNI 148 Query: 390 QEAIIHFREAIRLAPCRLDCYEGLIEC 416 EAI +R A++L P D Y L C Sbjct: 149 PEAIASYRTALKLKPDFPDAYCNLAHC 175 >5JJT-A nrPDB Length = 479 Score = 38.5 bits (88), Expect = 0.009, Method: Compositional matrix adjust. Identities = 20/64 (31%), Positives = 35/64 (54%) Query: 353 KRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEG 412 + Y A+ +KAI+++S + +GAA MG+ ++A+ F++ RL+P D Sbjct: 57 EEYGSAIQDASKAIEVDSRYSKGYYRRGAAYLAMGKFKDALKDFQQVKRLSPNDPDATRK 116 Query: 413 LIEC 416 L EC Sbjct: 117 LKEC 120 >5A01-A nrPDB Length = 710 Score = 36.6 bits (83), Expect = 0.030, Method: Compositional matrix adjust. Identities = 24/87 (27%), Positives = 43/87 (49%), Gaps = 15/87 (17%) Query: 359 LYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCY-------- 410 LYL KA+++ + A + L+ G+++EA++H++EAIR+ P D Y Sbjct: 29 LYL--KALEVFPDFAAAHSNLASVLQQQGKLKEALMHYKEAIRIQPTFADAYSNMGNTLK 86 Query: 411 -----EGLIECYLASNSIREAMVMANN 432 G ++CY + I A A++ Sbjct: 87 ELQDVSGALQCYTRAIQINPAFADAHS 113 Score = 32.0 bits (71), Expect = 0.86, Method: Compositional matrix adjust. Identities = 20/61 (32%), Positives = 29/61 (47%) Query: 356 SRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIE 415 S AL +AIQ+N A + ++ G + EAI +R A++L P D Y L Sbjct: 92 SGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIQSYRTALKLKPDFPDAYCNLAH 151 Query: 416 C 416 C Sbjct: 152 C 152 >5FZQ-A nrPDB Length = 131 Score = 33.9 bits (76), Expect = 0.19, Method: Compositional matrix adjust. Identities = 18/55 (32%), Positives = 31/55 (56%) Query: 269 DNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLED 323 +N+ L +LA+L + G + ++ +A LDP IK + LLA+EG+ E+ Sbjct: 37 NNIKTLSNLANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLAVLLAQEGKAEE 91 Score = 33.9 bits (76), Expect = 0.22, Method: Compositional matrix adjust. Identities = 32/134 (23%), Positives = 58/134 (43%), Gaps = 34/134 (25%) Query: 269 DNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLG 328 +++ L +LA+L + G + ++ +A LDP IK + LLA+EG+ E+ Sbjct: 3 NSIKTLSNLANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLANLLAQEGKAEE----- 57 Query: 329 CRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGR 388 + +Y R KA+ L+ N+++ L L G+ Sbjct: 58 -----------------------AIKYMR------KAVSLDPNNIKTLSNLAVLLAQEGK 88 Query: 389 VQEAIIHFREAIRL 402 +EAI + R+A+ L Sbjct: 89 AEEAIKYMRKAVSL 102 Score = 32.7 bits (73), Expect = 0.43, Method: Compositional matrix adjust. Identities = 23/77 (29%), Positives = 42/77 (54%), Gaps = 1/77 (1%) Query: 474 DYIKAVVKKAELLSREQKYEDGIALLRNALA-NQSDCVLHRILGDFLVAVNEYQEAMDQY 532 + IK + A LL++E K E+ I +R A++ + ++ L + L + +EA+ Sbjct: 3 NSIKTLSNLANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLANLLAQEGKAEEAIKYM 62 Query: 533 SIALSLDPNDQKSLEGM 549 A+SLDPN+ K+L + Sbjct: 63 RKAVSLDPNNIKTLSNL 79 Score = 30.8 bits (68), Expect = 1.9, Method: Compositional matrix adjust. Identities = 30/118 (25%), Positives = 53/118 (44%), Gaps = 35/118 (29%) Query: 387 GRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTL 446 G+ +EAI + R+A+ L P NN+ +TL+ Sbjct: 19 GKAEEAIKYMRKAVSLDP--------------------------NNI--------KTLSN 44 Query: 447 LATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALA 504 LA + ++ +E K + KA++ P+ IK + A LL++E K E+ I +R A++ Sbjct: 45 LANLLAQEGKAEEAIK-YMRKAVSLDPNNIKTLSNLAVLLAQEGKAEEAIKYMRKAVS 101 >5ZYQ-A nrPDB Length = 320 Score = 33.5 bits (75), Expect = 0.29, Method: Compositional matrix adjust. Identities = 28/118 (23%), Positives = 52/118 (44%), Gaps = 2/118 (1%) Query: 448 ATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQS 507 A CL + ++A L Q P+ I A++ KA + ++ Y +A + AL Sbjct: 135 ACFCLLEGDKMDQADAQFHFVLNQSPNNIPALLGKACISFNKKDYRGALAYYKKALRTNP 194 Query: 508 DCV--LHRILGDFLVAVNEYQEAMDQYSIALSLDPNDQKSLEGMQKMEKEESPTDATQ 563 C + +G V +N+ ++A +S AL L+ +L G+ +E D ++ Sbjct: 195 GCPAEVRLGMGHCFVKLNKLEKARLAFSRALELNSKCVGALVGLAVLELNNKEADGSE 252 >5MGX-E nrPDB Length = 290 Score = 33.5 bits (75), Expect = 0.29, Method: Compositional matrix adjust. Identities = 14/35 (40%), Positives = 25/35 (71%) Query: 469 LTQRPDYIKAVVKKAELLSREQKYEDGIALLRNAL 503 L +PD IKA+ +K ++L+++ +Y + I +LR AL Sbjct: 209 LEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAAL 243 >6B85-J nrPDB Length = 223 Score = 33.1 bits (74), Expect = 0.37, Method: Compositional matrix adjust. Identities = 22/72 (30%), Positives = 33/72 (45%) Query: 342 WVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIR 401 W++ G KR A KAI+L N A G L +GR+ EA +++AI Sbjct: 118 WLLLGSVLEKLKRLDEAAEAYKKAIELKPNDASAWKELGKVLEKLGRLDEAAEAYKKAIE 177 Query: 402 LAPCRLDCYEGL 413 L P + ++ L Sbjct: 178 LDPEDAEAWKEL 189 Score = 32.0 bits (71), Expect = 0.83, Method: Compositional matrix adjust. Identities = 29/117 (24%), Positives = 49/117 (41%) Query: 294 FEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSK 353 +++A LDP + G +L + RL++ + + A W G Sbjct: 104 YKKAIELDPNDALAWLLLGSVLEKLKRLDEAAEAYKKAIELKPNDASAWKELGKVLEKLG 163 Query: 354 RYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCY 410 R A KAI+L+ +A G L +GR+ EA +++AI L P L+ + Sbjct: 164 RLDEAAEAYKKAIELDPEDAEAWKELGKVLEKLGRLDEAAEAYKKAIELDPNDLEHH 220 >4I2W-A nrPDB Length = 961 Score = 31.6 bits (70), Expect = 1.1, Method: Compositional matrix adjust. Identities = 26/86 (30%), Positives = 40/86 (46%), Gaps = 6/86 (6%) Query: 354 RYSRALYLGA-----KAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLD 408 R R + GA KA++ + V+AL + A +G V A +EA+RL+P Sbjct: 57 RLKRDDFEGAQSDCTKALEFDGADVKALFRRSLAREQLGNVGPAFQDAKEALRLSPNDKG 116 Query: 409 CYEGLIECYLASN-SIREAMVMANNV 433 E L A+N I++ +AN V Sbjct: 117 IVEVLQRLVKANNDKIKQTTSLANKV 142 >2Y4T-A nrPDB Length = 450 Score = 31.2 bits (69), Expect = 1.3, Method: Compositional matrix adjust. Identities = 37/163 (22%), Positives = 70/163 (42%), Gaps = 24/163 (14%) Query: 236 LSVW------IKAYAFVHTGDNSRAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKN 289 + VW ++A F+ G+ +AIS + + K L DN + ++ LY++ GD++ Sbjct: 172 VCVWDAELRELRAECFIKEGEPRKAISDLKAASK--LKNDNTEAFYKISTLYYQLGDHEL 229 Query: 290 SVLKFEQAQMLDPYLIKGMDVYGYL------------LAREGRLEDVENLGCRLFNISDQ 337 S+ + + LD + Y + L R+GR D + + Sbjct: 230 SLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIESAEELIRDGRYTDATSKYESVMKTEPS 289 Query: 338 HAEPWVVSG---CHSF-YSKRYSRALYLGAKAIQLNSNSVQAL 376 AE V S CH F ++ A+ + ++ +Q+ ++V AL Sbjct: 290 IAEYTVRSKERICHCFSKDEKPVEAIRVCSEVLQMEPDNVNAL 332 >4GFK-A nrPDB Length = 196 Score = 29.3 bits (64), Expect = 4.5, Method: Compositional matrix adjust. Identities = 22/83 (26%), Positives = 43/83 (51%), Gaps = 13/83 (15%) Query: 18 RLFESVLPPLPAALQSRMN-VIDHVRDMAAAGLHSNVRLLSSLLLTMSNNNPELFSPPQK 76 R+FE ++ + +L SR+N + D +D + +RL+ LLL + NP L Sbjct: 55 RMFEGLIEFIEESLMSRINRIFDEEKDTL-----NRIRLVMQLLLAFAERNPGL------ 103 Query: 77 YQLLVYHADSLFHDKEYRNAVSK 99 ++L HA +F ++ R+ +++ Sbjct: 104 TRILSGHA-LMFENERLRDRINQ 125 >4TKZ-A nrPDB Length = 152 Score = 28.9 bits (63), Expect = 6.4, Method: Composition-based stats. Identities = 34/127 (26%), Positives = 54/127 (42%), Gaps = 9/127 (7%) Query: 474 DYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDF---LVAVNEYQEAMD 530 ++ ++ EL++ Q+Y GI + +N L R + DF LV + Sbjct: 11 NFPDGILSSLELIAGHQEYVVGINFIAGMSSNDVRVALQREVIDFKEILVLTDLLGGTPF 70 Query: 531 QYSIALSLDPNDQ--KSLEGMQKMEKEESPTDATQEEDVDDMEG----SGEEGDLEGSDS 584 S ALS++ D+ K L G+ E+ T E VDD+ S EG ++ S Sbjct: 71 NVSSALSVEYTDKKIKVLSGLNLSMLMEAVLSRTMFEHVDDLVDKVITSSHEGIVDFSTC 130 Query: 585 EAAQWAD 591 A Q A+ Sbjct: 131 LATQTAE 137 >5GVE-A nrPDB Length = 613 Score = 28.5 bits (62), Expect = 7.9, Method: Compositional matrix adjust. Identities = 23/80 (28%), Positives = 37/80 (46%), Gaps = 4/80 (5%) Query: 131 CLPSEIEVKYKMAECYTMLK----QDKDAIAILDGIPSRQRTPKINMMLANLYKKAGQER 186 C+ +++ E Y +L+ DKD +LD R +I M N+ K + + Sbjct: 226 CVERHDKIQSFKPETYWVLQAKVNTDKDRSLLLDWDRVRVFDREIAQMFLNMTKLEKEAQ 285 Query: 187 PSVTSYKEVLRQCPLALDAI 206 TS KE +Q PLAL+ + Sbjct: 286 VEATSRKEKAKQRPLALNTV 305 >2GW1-A nrPDB Length = 514 Score = 28.5 bits (62), Expect = 9.1, Method: Compositional matrix adjust. Identities = 20/76 (26%), Positives = 35/76 (46%), Gaps = 1/76 (1%) Query: 465 LDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCV-LHRILGDFLVAVN 523 DKA P+ I ++ A L RE K++D L A + + + L N Sbjct: 327 FDKAKELDPENIFPYIQLACLAYRENKFDDCETLFSEAKRKFPEAPEVPNFFAEILTDKN 386 Query: 524 EYQEAMDQYSIALSLD 539 ++ +A+ QY +A+ L+ Sbjct: 387 DFDKALKQYDLAIELE 402 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5G04-X nrPDB 992 0.0 5G04-F nrPDB 418 e-117 5G05-C nrPDB 265 3e-71 1W3B-A nrPDB 223 1e-58 Sequences not found previously or not previously below threshold: 6B85-J nrPDB 75 7e-14 5LVV-A nrPDB 73 3e-13 5KHR-J nrPDB 73 4e-13 5A01-A nrPDB 68 1e-11 5JJT-A nrPDB 54 2e-07 6FO1-G nrPDB 50 3e-06 5AEM-A nrPDB 50 4e-06 6C95-A nrPDB 49 5e-06 4ZLH-A nrPDB 49 7e-06 4JA9-A nrPDB 45 1e-04 5FZQ-A nrPDB 44 1e-04 2C2L-A nrPDB 44 2e-04 2GW1-A nrPDB 44 2e-04 1A17-A nrPDB 43 4e-04 5ZYQ-A nrPDB 43 5e-04 4ABN-A nrPDB 40 0.003 6AF0-A nrPDB 40 0.004 4I9E-A nrPDB 39 0.005 1QZ2-A nrPDB 39 0.007 5OQL-E nrPDB 39 0.008 5IC8-A nrPDB 39 0.008 4HOQ-A nrPDB 37 0.017 5DSE-A nrPDB 37 0.023 2Y4T-A nrPDB 37 0.032 4G1T-A nrPDB 37 0.033 4UZY-A nrPDB 36 0.065 4JHR-A nrPDB 36 0.069 2IF4-A nrPDB 35 0.12 5JZ6-A nrPDB 35 0.12 5NNP-A nrPDB 35 0.13 6FRK-r nrPDB 34 0.15 5OJF-A nrPDB 34 0.19 5JHE-A nrPDB 34 0.25 3ZFW-A nrPDB 33 0.32 6AHD-N nrPDB 33 0.32 5MGX-E nrPDB 33 0.35 5O09-1C nrPDB 33 0.47 5OMP-A nrPDB 32 0.50 6ICZ-I nrPDB 32 0.75 4KPA-A nrPDB 32 0.75 4CGU-A nrPDB 32 0.80 5UDI-A nrPDB 32 1.00 4HOU-A nrPDB 31 1.1 5GVE-A nrPDB 31 1.3 3ZN3-A nrPDB 31 1.4 3NF1-A nrPDB 31 1.7 5OJ8-A nrPDB 30 1.9 2GNO-A nrPDB 30 2.3 5C9S-B nrPDB 30 2.6 1KT1-A nrPDB 30 2.6 5NLG-A nrPDB 30 3.5 2N98-A nrPDB 30 3.6 4IN3-B nrPDB 30 3.7 4MT4-A nrPDB 29 4.8 4GFK-A nrPDB 29 5.3 6FUZ-A nrPDB 29 5.5 >5G04-X nrPDB Length = 599 Score = 992 bits (2565), Expect = 0.0, Method: Composition-based stats. Identities = 599/599 (100%), Positives = 599/599 (100%) Query: 1 MDPGDAAILESSLRILYRLFESVLPPLPAALQSRMNVIDHVRDMAAAGLHSNVRLLSSLL 60 MDPGDAAILESSLRILYRLFESVLPPLPAALQSRMNVIDHVRDMAAAGLHSNVRLLSSLL Sbjct: 1 MDPGDAAILESSLRILYRLFESVLPPLPAALQSRMNVIDHVRDMAAAGLHSNVRLLSSLL 60 Query: 61 LTMSNNNPELFSPPQKYQLLVYHADSLFHDKEYRNAVSKYTMALQQKKALSKTSKVRPST 120 LTMSNNNPELFSPPQKYQLLVYHADSLFHDKEYRNAVSKYTMALQQKKALSKTSKVRPST Sbjct: 61 LTMSNNNPELFSPPQKYQLLVYHADSLFHDKEYRNAVSKYTMALQQKKALSKTSKVRPST 120 Query: 121 GNSASTPQSQCLPSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQRTPKINMMLANLYK 180 GNSASTPQSQCLPSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQRTPKINMMLANLYK Sbjct: 121 GNSASTPQSQCLPSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQRTPKINMMLANLYK 180 Query: 181 KAGQERPSVTSYKEVLRQCPLALDAILGLLSLSVKGAEVASMTMNVIQTVPNLDWLSVWI 240 KAGQERPSVTSYKEVLRQCPLALDAILGLLSLSVKGAEVASMTMNVIQTVPNLDWLSVWI Sbjct: 181 KAGQERPSVTSYKEVLRQCPLALDAILGLLSLSVKGAEVASMTMNVIQTVPNLDWLSVWI 240 Query: 241 KAYAFVHTGDNSRAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQML 300 KAYAFVHTGDNSRAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQML Sbjct: 241 KAYAFVHTGDNSRAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQML 300 Query: 301 DPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALY 360 DPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALY Sbjct: 301 DPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALY 360 Query: 361 LGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLAS 420 LGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLAS Sbjct: 361 LGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLAS 420 Query: 421 NSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVV 480 NSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVV Sbjct: 421 NSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVV 480 Query: 481 KKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDP 540 KKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDP Sbjct: 481 KKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDP 540 Query: 541 NDQKSLEGMQKMEKEESPTDATQEEDVDDMEGSGEEGDLEGSDSEAAQWADQEQWFGMQ 599 NDQKSLEGMQKMEKEESPTDATQEEDVDDMEGSGEEGDLEGSDSEAAQWADQEQWFGMQ Sbjct: 541 NDQKSLEGMQKMEKEESPTDATQEEDVDDMEGSGEEGDLEGSDSEAAQWADQEQWFGMQ 599 >5G04-F nrPDB Length = 824 Score = 418 bits (1074), Expect = e-117, Method: Composition-based stats. Identities = 100/496 (20%), Positives = 190/496 (38%), Gaps = 34/496 (6%) Query: 101 TMALQQKKALSKTSKVRPSTGNSASTPQSQCLPSEIEVKYKMAECYTMLKQDKDAIAILD 160 T L Q ++ + P + T LP + T K + Sbjct: 343 TPILAQTQSSGPQTSTTPQVLSPTITSPPNALPRRSSRLFTSDSSTTKENSKKLKMKFPP 402 Query: 161 GIPSRQRTPKINMMLANLYKKAGQERPSVTSYKEVLRQCPLALDA-ILGLLSLSVKGAEV 219 IP+R+ K N K G +P++ E+ + LD+ I+ +S ++ Sbjct: 403 KIPNRKTKSKTN--------KGGITQPNINDSLEITK-----LDSSIISEGKISTITPQI 449 Query: 220 ASMTMNVIQTVPNLDWLSVWIKAYAFVHTGDNSRAISTICSLEKKSLLRDNVDLLGSLAD 279 + + + L K Y + + + AI+ + L + +L + Sbjct: 450 QAFNLQKAAAEGLMSLLREMGKGYLALCSYNCKEAINILSHLPSHH--YNTGWVLCQIGR 507 Query: 280 LYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHA 339 YF + + F + + ++ Y ++GM++Y L + + L L ++ Sbjct: 508 AYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTDMDKNSP 567 Query: 340 EPWVVSG-CHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFRE 398 E W +G C S + + A+ +AIQ++ N A L G + +A+ FR Sbjct: 568 EAWCAAGNCFSLQ-REHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRN 626 Query: 399 AIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQ 458 AIR+ P + + GL Y A + + K L N Q+ LL + + + Sbjct: 627 AIRVNPRHYNAWYGLGMIYYKQEKFSLAEM---HFQKALDINPQSSVLLCHIGVVQHALK 683 Query: 459 --EKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDG---IALLRNALANQSDCVLHR 513 EKA L+KA+ P +A +L +KY+ + L+ + +S +++ Sbjct: 684 KSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKES--LVYF 741 Query: 514 ILGDFLVAVNEYQEAMDQYSIALSLDP----NDQKSLEGMQKMEKEESPTDATQEEDVDD 569 ++G + + A+ +S A+ LDP N K + + +E P TQEE + Sbjct: 742 LIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEEPI--TQEEQIMG 799 Query: 570 MEGSGEEGDLEGSDSE 585 + S E + D++ Sbjct: 800 TDESQESSMTDADDTQ 815 Score = 35.1 bits (79), Expect = 0.093, Method: Composition-based stats. Identities = 13/77 (16%), Positives = 23/77 (29%), Gaps = 7/77 (9%) Query: 340 EPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREA 399 E + G + G A L L G R+ + ++++ Sbjct: 89 EQILSGGVFNKQKSHDDIVTEFGDSA-------CFTLSLLGHVYCKTDRLAKGSECYQKS 141 Query: 400 IRLAPCRLDCYEGLIEC 416 + L P +E L E Sbjct: 142 LSLNPFLWSPFESLCEI 158 >5G05-C nrPDB Length = 597 Score = 265 bits (678), Expect = 3e-71, Method: Composition-based stats. Identities = 62/272 (22%), Positives = 101/272 (37%), Gaps = 17/272 (6%) Query: 225 NVIQTVPNLDWLSV---WIKAYAFVHTGDNSRAISTICSLEKKSLLRD-----NVDLLGS 276 N+I L +LS+ W+K + H + I +L+K L D + ++ Sbjct: 211 NLITDKEMLKFLSLPDTWMKEFFLAHIYTELQLIEE--ALQKYQNLIDVGFSKSSYIVSQ 268 Query: 277 LADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISD 336 +A Y D ++ F + + DPY I+ MD + LL ++ L L I Sbjct: 269 IAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDK 328 Query: 337 QHAEPWVVSG-CHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIH 395 E V G +S S+ ALY +A++LN + A L G M AI Sbjct: 329 YRVETCCVIGNYYSLRSQHEKAALYF-QRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQA 387 Query: 396 FREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATV--CLE 453 +R AI + + GL + Y ++ + +L + C E Sbjct: 388 YRHAIEVNKRDYRAWYGLGQTY---EILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYE 444 Query: 454 DPVTQEKAKTLLDKALTQRPDYIKAVVKKAEL 485 +AK +A A+VK A+L Sbjct: 445 KLNQLVEAKKCYWRAYAVGDVEKMALVKLAKL 476 Score = 35.9 bits (81), Expect = 0.045, Method: Composition-based stats. Identities = 45/307 (14%), Positives = 99/307 (32%), Gaps = 46/307 (14%) Query: 276 SLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNIS 335 +LA YF + + Y + +Y L+ E + +D Sbjct: 88 TLAKAYFDVKEYDRAAHFLHGCNSKKAYFLY---MYSRYLSGEKKKDDETVDSLGPLEKG 144 Query: 336 DQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIH 395 E R + A+ + + G LR + V+EAI Sbjct: 145 QVKNEA--------LRELRVELSKKHQARELDGFGLYLY-----GVVLRKLDLVKEAIDV 191 Query: 396 FREAIRLAPCRLDCYEGLIEC--------YLASNSIREAMVMANNVYKTLGA-------- 439 F EA + P + L +L+ ++Y L Sbjct: 192 FVEATHVLPLHWGAWLELCNLITDKEMLKFLSLPDTWMKEFFLAHIYTELQLIEEALQKY 251 Query: 440 -------NAQTLTLLATVCLEDPVTQ--EKAKTLLDKALTQRPDYIKAVVKKAELLSREQ 490 +++ +++ + + + +KA ++ ++ Q P Y + L + Sbjct: 252 QNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDP-YRIENMDTFSNLLYVR 310 Query: 491 KYEDGIALLRNALANQSDCVLHR--ILGDFLVAVNEYQEAMDQYSIALSLDPNDQK--SL 546 + ++ L + L + ++G++ +++++A + AL L+P +L Sbjct: 311 SMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTL 370 Query: 547 EGMQKME 553 G + ME Sbjct: 371 MGHEYME 377 >1W3B-A nrPDB Length = 388 Score = 223 bits (569), Expect = 1e-58, Method: Composition-based stats. Identities = 55/208 (26%), Positives = 89/208 (42%), Gaps = 19/208 (9%) Query: 343 VVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRL 402 ++S H F +R R+ + AI+ N +A G + G++QEAI H+R A+RL Sbjct: 38 LLSSIH-FQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRL 96 Query: 403 APCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVC--LEDPVTQEK 460 P +D Y L +A+ + E V A L N + + + L+ E+ Sbjct: 97 KPDFIDGYINLAAALVAAGDM-EGAVQA--YVSALQYNPDLYCVRSDLGNLLKALGRLEE 153 Query: 461 AKTLLDKALTQRPDYIKA-------VVKKAELLSREQKYEDGIALLRNALANQSDCVLHR 513 AK KA+ +P++ A + E+ +E + L N L D ++ Sbjct: 154 AKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFL----DAYIN- 208 Query: 514 ILGDFLVAVNEYQEAMDQYSIALSLDPN 541 LG+ L + A+ Y ALSL PN Sbjct: 209 -LGNVLKEARIFDRAVAAYLRALSLSPN 235 Score = 101 bits (252), Expect = 9e-22, Method: Composition-based stats. Identities = 60/273 (21%), Positives = 101/273 (36%), Gaps = 2/273 (0%) Query: 269 DNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLG 328 D +D +LA AGD + +V + A +P L G LL GRLE+ + Sbjct: 99 DFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACY 158 Query: 329 CRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGR 388 + A W GC A++ KA+ L+ N + A + G L+ Sbjct: 159 LKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARI 218 Query: 389 VQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLA 448 A+ + A+ L+P + L Y I A+ + LA Sbjct: 219 FDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLA 278 Query: 449 TVCLEDPVTQEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSD 508 L++ + +A+ + AL P + ++ A + + E+ + L R AL + Sbjct: 279 N-ALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPE 337 Query: 509 -CVLHRILGDFLVAVNEYQEAMDQYSIALSLDP 540 H L L + QEA+ Y A+ + P Sbjct: 338 FAAAHSNLASVLQQQGKLQEALMHYKEAIRISP 370 Score = 91.0 bits (224), Expect = 1e-18, Method: Composition-based stats. Identities = 58/307 (18%), Positives = 111/307 (36%), Gaps = 30/307 (9%) Query: 269 DNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRL-EDVENL 327 DN +L L+ ++F+ S A +P L + G + G+L E +E+ Sbjct: 31 DNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHY 90 Query: 328 GCRLFNISDQHAEPWVVSGCHSFYSK-----RYSRALYLGAKAIQLNSNSVQALLLKGAA 382 L +P + G + + A+ A+Q N + G Sbjct: 91 RHAL------RLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNL 144 Query: 383 LRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQ 442 L+ +GR++EA + +AI P + L + A I A+ ++ K + + Sbjct: 145 LKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAI---HHFEKAVTLDPN 201 Query: 443 TLTLLATVC--LEDPVTQEKAKTLLDKALTQRPDYIK-------AVVKKAELLSREQKYE 493 L + L++ ++A +AL+ P++ ++ + Y Sbjct: 202 FLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYR 261 Query: 494 DGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDPNDQKSLEGMQKME 553 I L + D + L + L EA D Y+ AL L P SL + ++ Sbjct: 262 RAIELQPHF----PDAYCN--LANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIK 315 Query: 554 KEESPTD 560 +E+ + Sbjct: 316 REQGNIE 322 Score = 60.9 bits (146), Expect = 1e-09, Method: Composition-based stats. Identities = 34/162 (20%), Positives = 66/162 (40%) Query: 261 LEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGR 320 L SL ++ + G+LA +Y+ G ++ + +A L P+ L +G Sbjct: 227 LRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGS 286 Query: 321 LEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKG 380 + + E+ + HA+ A+ L KA+++ A Sbjct: 287 VAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLA 346 Query: 381 AALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNS 422 + L+ G++QEA++H++EAIR++P D Y + Sbjct: 347 SVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQD 388 >6B85-J nrPDB Length = 223 Score = 75.2 bits (183), Expect = 7e-14, Method: Composition-based stats. Identities = 29/119 (24%), Positives = 49/119 (41%), Gaps = 5/119 (4%) Query: 358 ALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECY 417 A KAI+L+ N A LL G+ L + R+ EA +++AI L P ++ L + Sbjct: 100 AAEAYKKAIELDPNDALAWLLLGSVLEKLKRLDEAAEAYKKAIELKPNDASAWKELGKVL 159 Query: 418 LASNSIREAMVMANNVYKTLGANAQTLTLLATVC--LEDPVTQEKAKTLLDKALTQRPD 474 + EA A K + + + + LE ++A KA+ P+ Sbjct: 160 EKLGRLDEA---AEAYKKAIELDPEDAEAWKELGKVLEKLGRLDEAAEAYKKAIELDPN 215 Score = 68.6 bits (166), Expect = 7e-12, Method: Composition-based stats. Identities = 28/116 (24%), Positives = 45/116 (38%), Gaps = 3/116 (2%) Query: 329 CRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGR 388 + + A W++ G KR A KAI+L N A G L +GR Sbjct: 105 KKAIELDPNDALAWLLLGSVLEKLKRLDEAAEAYKKAIELKPNDASAWKELGKVLEKLGR 164 Query: 389 VQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTL 444 + EA +++AI L P + ++ L + + EA A K + + L Sbjct: 165 LDEAAEAYKKAIELDPEDAEAWKELGKVLEKLGRLDEA---AEAYKKAIELDPNDL 217 Score = 57.8 bits (138), Expect = 1e-08, Method: Composition-based stats. Identities = 28/124 (22%), Positives = 45/124 (36%), Gaps = 15/124 (12%) Query: 430 ANNVYKTLGANAQ--TLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVVKKAELLS 487 A K + + LL LE ++A KA+ +P+ A + ++L Sbjct: 101 AEAYKKAIELDPNDALAWLLLGSVLEKLKRLDEAAEAYKKAIELKPNDASAWKELGKVLE 160 Query: 488 -------REQKYEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDP 540 + Y+ I L D + LG L + EA + Y A+ LDP Sbjct: 161 KLGRLDEAAEAYKKAIELDPE------DAEAWKELGKVLEKLGRLDEAAEAYKKAIELDP 214 Query: 541 NDQK 544 ND + Sbjct: 215 NDLE 218 Score = 54.0 bits (128), Expect = 2e-07, Method: Composition-based stats. Identities = 29/119 (24%), Positives = 49/119 (41%) Query: 290 SVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHS 349 + +++A LDP + G +L + RL++ + + A W G Sbjct: 100 AAEAYKKAIELDPNDALAWLLLGSVLEKLKRLDEAAEAYKKAIELKPNDASAWKELGKVL 159 Query: 350 FYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLD 408 R A KAI+L+ +A G L +GR+ EA +++AI L P L+ Sbjct: 160 EKLGRLDEAAEAYKKAIELDPEDAEAWKELGKVLEKLGRLDEAAEAYKKAIELDPNDLE 218 Score = 49.0 bits (115), Expect = 6e-06, Method: Composition-based stats. Identities = 22/105 (20%), Positives = 45/105 (42%), Gaps = 1/105 (0%) Query: 461 AKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALA-NQSDCVLHRILGDFL 519 A KA+ P+ A + +L + ++ ++ + A+ +D + LG L Sbjct: 100 AAEAYKKAIELDPNDALAWLLLGSVLEKLKRLDEAAEAYKKAIELKPNDASAWKELGKVL 159 Query: 520 VAVNEYQEAMDQYSIALSLDPNDQKSLEGMQKMEKEESPTDATQE 564 + EA + Y A+ LDP D ++ + + K+ ++ D E Sbjct: 160 EKLGRLDEAAEAYKKAIELDPEDAEAWKELGKVLEKLGRLDEAAE 204 >5LVV-A nrPDB Length = 749 Score = 73.3 bits (178), Expect = 3e-13, Method: Composition-based stats. Identities = 30/157 (19%), Positives = 63/157 (40%), Gaps = 5/157 (3%) Query: 356 SRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIE 415 A+ L KA+++ A + L+ G++QEA++H++EAIR++P D Y + Sbjct: 47 EEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGN 106 Query: 416 CYLASNSIREAMVMANNVYKTLGANAQTLTLLATVCL--EDPVTQEKAKTLLDKALTQRP 473 + + + + + N + + +D +A AL +P Sbjct: 107 TLKEMQDV-QGALQC--YTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKP 163 Query: 474 DYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCV 510 D+ A A L + D ++ ++ +D + Sbjct: 164 DFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQL 200 Score = 67.5 bits (163), Expect = 1e-11, Method: Composition-based stats. Identities = 23/101 (22%), Positives = 37/101 (36%) Query: 351 YSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCY 410 + AL +AI+++ A G L+ M VQ A+ + AI++ P D + Sbjct: 76 QQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAH 135 Query: 411 EGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVC 451 L + S +I EA+ K LA Sbjct: 136 SNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCL 176 Score = 62.1 bits (149), Expect = 7e-10, Method: Composition-based stats. Identities = 19/140 (13%), Positives = 48/140 (34%), Gaps = 12/140 (8%) Query: 372 SVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMAN 431 +L R G ++EA+ +R+A+ + P + L ++EA++ Sbjct: 29 HADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALM--- 85 Query: 432 NVYKTLGANAQTLTLLATVC--LEDPVTQEKAKTLLDKALTQRPDYI-----KAVVKK-- 482 + + + + + + L++ + A +A+ P + A + K Sbjct: 86 HYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDS 145 Query: 483 AELLSREQKYEDGIALLRNA 502 + Y + L + Sbjct: 146 GNIPEAIASYRTALKLKPDF 165 Score = 47.8 bits (112), Expect = 1e-05, Method: Composition-based stats. Identities = 26/106 (24%), Positives = 51/106 (48%), Gaps = 6/106 (5%) Query: 438 GANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIA 497 G +A +L LA + E E+A L KAL P++ A A +L ++ K ++ + Sbjct: 27 GTHADSLNNLANIKREQ-GNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALM 85 Query: 498 LLRNAL---ANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDP 540 + A+ +D + +G+ L + + Q A+ Y+ A+ ++P Sbjct: 86 HYKEAIRISPTFADAYSN--MGNTLKEMQDVQGALQCYTRAIQINP 129 >5KHR-J nrPDB Length = 620 Score = 72.9 bits (177), Expect = 4e-13, Method: Composition-based stats. Identities = 50/301 (16%), Positives = 104/301 (34%), Gaps = 18/301 (5%) Query: 256 STICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLL 315 S E L++N+D++ SLA+ ++ D K DP+ + V+ L Sbjct: 216 SETVIPESVDGLQENLDVVVSLAERHYYNCDFKMCYKLTSVVMEKDPFHASCLPVHIGTL 275 Query: 316 AREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSR-ALYLGAKAIQLNSNSVQ 374 + ++ L +L ++ + W GC+ + A +KA L Sbjct: 276 VELNKANELFYLSHKLVDLYPSNPVSWFAVGCYYLMVGHKNEHARRYLSKATTLEKTYGP 335 Query: 375 ALLLKGAALRNMGRVQEAIIHFREAIRLAP-CRLDCYEGLIECYLASNSIREAMVMANNV 433 A + G + +A+ + A +L C L + Y +N+ + A Sbjct: 336 AWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLY-IGLEYGLTNNSKLAE---RFF 391 Query: 434 YKTLGANAQTLTLLATVCLE--DPVTQEKAKTLLDKALT---------QRPDYIKAVVKK 482 + L + ++ V + + A+ AL + + Sbjct: 392 SQALSIAPEDPFVMHEVGVVAFQNGEWKTAEKWFLDALEKIKAIGNEVTVDKWEPLLNNL 451 Query: 483 AELLSREQKYEDGIALLRNALAN-QSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDPN 541 + + +KY + + R AL + + +G + ++ A+D + AL L + Sbjct: 452 GHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRD 511 Query: 542 D 542 D Sbjct: 512 D 512 >5A01-A nrPDB Length = 710 Score = 68.2 bits (165), Expect = 1e-11, Method: Composition-based stats. Identities = 28/133 (21%), Positives = 53/133 (39%), Gaps = 5/133 (3%) Query: 356 SRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIE 415 A L KA+++ + A + L+ G+++EA++H++EAIR+ P D Y + Sbjct: 24 EEATRLYLKALEVFPDFAAAHSNLASVLQQQGKLKEALMHYKEAIRIQPTFADAYSNMGN 83 Query: 416 CYLASNSIREAMVMANNVYKTLGANAQTLTLLATVCL--EDPVTQEKAKTLLDKALTQRP 473 + A+ + + N + + +D +A AL +P Sbjct: 84 TLKELQDVSGAL---QCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIQSYRTALKLKP 140 Query: 474 DYIKAVVKKAELL 486 D+ A A L Sbjct: 141 DFPDAYCNLAHCL 153 Score = 66.7 bits (161), Expect = 3e-11, Method: Composition-based stats. Identities = 32/177 (18%), Positives = 55/177 (31%), Gaps = 5/177 (2%) Query: 351 YSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCY 410 + AL +AI++ A G L+ + V A+ + AI++ P D + Sbjct: 53 QQGKLKEALMHYKEAIRIQPTFADAYSNMGNTLKELQDVSGALQCYTRAIQINPAFADAH 112 Query: 411 EGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVCLE-----DPVTQEKAKTLL 465 L + S +I EA+ K LA D + K + Sbjct: 113 SNLASIHKDSGNIPEAIQSYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDIRMKKLVSI 172 Query: 466 DKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVAV 522 ++ + L IA L + VLH+ +FL + Sbjct: 173 VTEQLEKNRLPSVHPHHSMLYPLTHDCRKAIAARHANLCLEKVHVLHKKPYNFLKKL 229 Score = 63.6 bits (153), Expect = 2e-10, Method: Composition-based stats. Identities = 33/149 (22%), Positives = 61/149 (40%) Query: 269 DNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLG 328 ++ D L +LA++ G + + + +A + P +L ++G+L++ Sbjct: 5 NHADSLNNLANIKREQGYIEEATRLYLKALEVFPDFAAAHSNLASVLQQQGKLKEALMHY 64 Query: 329 CRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGR 388 I A+ + G + S AL +AIQ+N A + ++ G Sbjct: 65 KEAIRIQPTFADAYSNMGNTLKELQDVSGALQCYTRAIQINPAFADAHSNLASIHKDSGN 124 Query: 389 VQEAIIHFREAIRLAPCRLDCYEGLIECY 417 + EAI +R A++L P D Y L C Sbjct: 125 IPEAIQSYRTALKLKPDFPDAYCNLAHCL 153 Score = 48.2 bits (113), Expect = 1e-05, Method: Composition-based stats. Identities = 25/104 (24%), Positives = 49/104 (47%), Gaps = 6/104 (5%) Query: 440 NAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALL 499 +A +L LA + E E+A L KAL PD+ A A +L ++ K ++ + Sbjct: 6 HADSLNNLANIKREQ-GYIEEATRLYLKALEVFPDFAAAHSNLASVLQQQGKLKEALMHY 64 Query: 500 RNAL---ANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDP 540 + A+ +D + +G+ L + + A+ Y+ A+ ++P Sbjct: 65 KEAIRIQPTFADAYSN--MGNTLKELQDVSGALQCYTRAIQINP 106 >5JJT-A nrPDB Length = 479 Score = 53.6 bits (127), Expect = 2e-07, Method: Composition-based stats. Identities = 26/111 (23%), Positives = 41/111 (36%) Query: 333 NISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEA 392 N AE + +F +YS A+ L KAI+LNSN+ + A + A Sbjct: 3 NSDVSRAEEFKSQANEAFKGHKYSSAIDLYTKAIELNSNNAVYWANRAFAHTKLEEYGSA 62 Query: 393 IIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQT 443 I +AI + Y YLA ++A+ V + + Sbjct: 63 IQDASKAIEVDSRYSKGYYRRGAAYLAMGKFKDALKDFQQVKRLSPNDPDA 113 Score = 45.5 bits (106), Expect = 7e-05, Method: Composition-based stats. Identities = 25/107 (23%), Positives = 45/107 (42%), Gaps = 8/107 (7%) Query: 333 NISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEA 392 ++ +A W + Y A+ +KAI+++S + +GAA MG+ ++A Sbjct: 37 ELNSNNAVYWANRAFAHTKLEEYGSAIQDASKAIEVDSRYSKGYYRRGAAYLAMGKFKDA 96 Query: 393 IIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGA 439 + F++ RL+P D L EC E VM + + Sbjct: 97 LKDFQQVKRLSPNDPDATRKLKEC--------EKAVMKLKFEEAISV 135 Score = 33.2 bits (74), Expect = 0.30, Method: Composition-based stats. Identities = 26/169 (15%), Positives = 56/169 (33%), Gaps = 24/169 (14%) Query: 433 VYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLD--KALTQRPDYIKAVVKKAELLSREQ 490 K + N+ A +E + D KA+ Y K ++ Sbjct: 32 YTKAIELNSNNAVYWANRAFAHTKLEEYGSAIQDASKAIEVDSRYSKGYYRRGAAYLAMG 91 Query: 491 KYEDGI---ALLRNALANQSDCVLHRILGDFLVAVNEYQEAMD--QYSIALSLDPNDQKS 545 K++D + ++ N D + E ++A+ ++ A+S+ ++++S Sbjct: 92 KFKDALKDFQQVKRLSPNDPDAT---------RKLKECEKAVMKLKFEEAISVPVSERRS 142 Query: 546 -LEGMQKMEKEESPTDATQEEDVDDMEGSGEEGDLEGSDSEAAQWADQE 593 E + E P GEE L+ + + +Q+ Sbjct: 143 VAESIDFHTIEVEP-------QYSGARIEGEEVTLDFVKTMMEDFKNQK 184 >6FO1-G nrPDB Length = 665 Score = 49.8 bits (117), Expect = 3e-06, Method: Composition-based stats. Identities = 37/219 (16%), Positives = 71/219 (32%), Gaps = 13/219 (5%) Query: 350 FYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDC 409 F K+++ A A+ LN + +A +GAA + +++EA + + L P + Sbjct: 178 FRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEA 237 Query: 410 YEGLIEC----------YLASNSIREAMVMANNVYKTLGANAQTLTLLATVC--LEDPVT 457 L + Y I N Q Sbjct: 238 TNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGK 297 Query: 458 QEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRN-ALANQSDCVLHRILG 516 E+A + + +A + QKYE+ L + S G Sbjct: 298 YERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRG 357 Query: 517 DFLVAVNEYQEAMDQYSIALSLDPNDQKSLEGMQKMEKE 555 + + EA + L L+P +++++ + K++KE Sbjct: 358 TARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKE 396 Score = 42.4 bits (98), Expect = 5e-04, Method: Composition-based stats. Identities = 41/241 (17%), Positives = 78/241 (32%), Gaps = 52/241 (21%) Query: 365 AIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAP-------CRLDCYEGLIECY 417 I ++S L KG G+ EAI + + + P R Y L + Sbjct: 125 GIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFA 184 Query: 418 LASNSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIK 477 +A + A+ + + K E+AK ++ L P+ + Sbjct: 185 VAESDCNLAVALNRSYTKAYS--------RRGAARFALQKLEEAKKDYERVLELEPNNFE 236 Query: 478 AVVKKAELLSREQKYEDGIALLRNALANQSDCVL---------------------HRILG 516 A + +K +A N+ ++D V+ + G Sbjct: 237 ATNE-------LRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRG 289 Query: 517 DFLVAVNEYQEAMDQYSIALSLD-------PNDQKSLEGMQKMEKEESPTDATQEEDVDD 569 + +Y+ A++ Y+ ++ D N + +QK E+ E D TQ +D Sbjct: 290 NGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEK--DCTQAILLDG 347 Query: 570 M 570 Sbjct: 348 S 348 >5AEM-A nrPDB Length = 447 Score = 49.8 bits (117), Expect = 4e-06, Method: Composition-based stats. Identities = 28/164 (17%), Positives = 61/164 (37%), Gaps = 1/164 (0%) Query: 273 LLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLF 332 LL + + R D + + F + D + G + +GRL D N Sbjct: 12 LLSQANEAFVR-NDLQVAERLFNEVIKKDARNFAAYETLGDIYQLQGRLNDCCNSWFLAA 70 Query: 333 NISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEA 392 +++ E W + S +A+Y ++ I LN +++ + + G++ A Sbjct: 71 HLNASDWEFWKIVAILSADLDHVRQAIYCFSRVISLNPMEWESIYRRSMLYKKTGQLARA 130 Query: 393 IIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKT 436 + F+ P + L Y+ + I +++ + V+ Sbjct: 131 LDGFQRLYMYNPYDANILRELAILYVDYDRIEDSIELYMKVFNA 174 Score = 36.7 bits (83), Expect = 0.027, Method: Composition-based stats. Identities = 38/233 (16%), Positives = 85/233 (36%), Gaps = 23/233 (9%) Query: 365 AIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIR 424 A+ L+ Q L A +Q A F E I+ YE L + Y + Sbjct: 2 AMVLDPEVAQLLSQANEAFV-RNDLQVAERLFNEVIKKDARNFAAYETLGDIYQLQGRLN 60 Query: 425 EAMVMANNVYKTLGANAQTLTL--LATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVVKK 482 + N+ + NA + + D +A + ++ P +++ ++ Sbjct: 61 DC---CNSWFLAAHLNASDWEFWKIVAILSADLDHVRQAIYCFSRVISLNPMEWESIYRR 117 Query: 483 AELLSREQKYEDGIA-LLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDPN 541 + L + + + R + N D + R L V + +++++ Y + + Sbjct: 118 SMLYKKTGQLARALDGFQRLYMYNPYDANILRELAILYVDYDRIEDSIELYMKVFNAN-- 175 Query: 542 DQKSLEGMQKMEKEESPTDATQEEDVDDMEGSGEEGDLEGSDSEAAQWADQEQ 594 +E+ E+ A + + ++ S EE EG D++ + +Q++ Sbjct: 176 ----------VERREAILAALE----NALDSSDEESAAEGEDADEKEPLEQDE 214 Score = 34.0 bits (76), Expect = 0.21, Method: Composition-based stats. Identities = 13/73 (17%), Positives = 24/73 (32%), Gaps = 1/73 (1%) Query: 351 YSKRYSRALYLGAKAIQLNS-NSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDC 409 +++Y A+ + L + + + + A + AI+ P LD Sbjct: 360 RAEKYKEAIDFFTPLLSLEEWRTTDVFKPLARCYKEIESYETAKEFYELAIKSEPDDLDI 419 Query: 410 YEGLIECYLASNS 422 L E Y N Sbjct: 420 RVSLAEVYYRLND 432 >6C95-A nrPDB Length = 866 Score = 49.4 bits (116), Expect = 5e-06, Method: Composition-based stats. Identities = 43/245 (17%), Positives = 78/245 (31%), Gaps = 14/245 (5%) Query: 306 KGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKA 365 + + + G L G+ E+ L R + W V G K+Y A+ A Sbjct: 47 ETLAMKGLTLNCLGKKEEAYELVRRGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNA 106 Query: 366 IQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIRE 425 ++ + +++Q L M ++ + ++L P + + G Y Sbjct: 107 LKWDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEM 166 Query: 426 AMVMANNVYKTLGANAQT-------LTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKA 478 A + KT + L L L + +A L Q D + Sbjct: 167 AAKILEEFRKTQQTSPDKVDYEYSELLLYQNQVLREAGLYREALEHLCTYEKQICDKLAV 226 Query: 479 VVKKAELLSREQKYEDGIALLRNALANQSDCVLHR-------ILGDFLVAVNEYQEAMDQ 531 K ELL + + ED + R + + + L + Y+EA + Sbjct: 227 EETKGELLLQLCRLEDAADVYRGLQERNPENWAYYKGLEKALKPANMLERLKIYEEAWTK 286 Query: 532 YSIAL 536 Y L Sbjct: 287 YPRGL 291 >4ZLH-A nrPDB Length = 339 Score = 48.6 bits (114), Expect = 7e-06, Method: Composition-based stats. Identities = 35/228 (15%), Positives = 72/228 (31%), Gaps = 14/228 (6%) Query: 253 RAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYG 312 + + SL + L + L Y AG + F Q + I + Sbjct: 43 QTLMESASLTYEQRLL----AIQQLGRDYMAAGLYDRAEDMFNQLTDETDFRIGALQQLL 98 Query: 313 YLLAREGRLEDVENLGCRLFNI--SDQHAEP---WVVSGCHSFYSKRYSRALYLGAKAIQ 367 + + ++ RL + Q E + S RA+ L K Sbjct: 99 QIYQATSEWQKAIDVAERLVKLGKDKQRVEIAHFYCELALQHMASDDLDRAMTLLKKGAA 158 Query: 368 LNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAM 427 + NS + ++ G G +A+ + I + +++ + + Sbjct: 159 ADKNSARVSIMMGRVFMAKGEYAKAVESLQRVISQDRELVSETLEMLQTCYQQ--LGKTA 216 Query: 428 VMANNVYKTLGAN--AQTLTLLATVCLEDPVTQEKAKTLLDKALTQRP 473 A + + + N A +LA + +E E A+ + + L + P Sbjct: 217 EWAEFLQRAVEENTGADAELMLADI-IEARDGSEAAQVYITRQLQRHP 263 >4JA9-A nrPDB Length = 488 Score = 44.7 bits (104), Expect = 1e-04, Method: Composition-based stats. Identities = 19/86 (22%), Positives = 31/86 (36%) Query: 350 FYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDC 409 F +K Y A+ ++AI+LN ++ + A A+ AI L + Sbjct: 28 FKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKG 87 Query: 410 YEGLIECYLASNSIREAMVMANNVYK 435 Y +A R A+ V K Sbjct: 88 YYRRAASNMALGKFRAALRDYETVVK 113 Score = 39.4 bits (90), Expect = 0.005, Method: Composition-based stats. Identities = 24/163 (14%), Positives = 58/163 (35%), Gaps = 36/163 (22%) Query: 278 ADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQ 337 A+ YF+A D +N++ + QA L+P + Sbjct: 24 ANDYFKAKDYENAIKFYSQAIELNP---------SNAIYY------------------GN 56 Query: 338 HAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFR 397 + ++ + C+ + AL +AI+L+ ++ + A+ +G+ + A+ + Sbjct: 57 RSLAYLRTECYGY-------ALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYE 109 Query: 398 EAIRLAPCRLDCYEGLIEC--YLASNSIREAMVMANNVYKTLG 438 +++ P D EC + + A+ + + Sbjct: 110 TVVKVKPNDKDAKMKYQECSKIVKQKAFERAIAGDEHRRSVVD 152 Score = 29.7 bits (65), Expect = 3.4, Method: Composition-based stats. Identities = 22/161 (13%), Positives = 41/161 (25%), Gaps = 38/161 (23%) Query: 373 VQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANN 432 + L + + AI + +AI L P Y YL + A+ A Sbjct: 17 AEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDAT- 75 Query: 433 VYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKY 492 +A+ YIK ++A K+ Sbjct: 76 ----------------------------------RAIELDKKYIKGYYRRAASNMALGKF 101 Query: 493 EDGIALLRNAL---ANQSDCVLHRILGDFLVAVNEYQEAMD 530 + + N D + +V ++ A+ Sbjct: 102 RAALRDYETVVKVKPNDKDAKMKYQECSKIVKQKAFERAIA 142 >5FZQ-A nrPDB Length = 131 Score = 44.4 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 21/96 (21%), Positives = 37/96 (38%) Query: 351 YSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCY 410 + A+ KA+ L+ N+++ L L G+ +EAI + R+A+ L P + Sbjct: 17 QEGKAEEAIKYMRKAVSLDPNNIKTLSNLANLLAQEGKAEEAIKYMRKAVSLDPNNIKTL 76 Query: 411 EGLIECYLASNSIREAMVMANNVYKTLGANAQTLTL 446 L EA+ + A+ TL Sbjct: 77 SNLAVLLAQEGKAEEAIKYMRKAVSLIDKAAKGSTL 112 Score = 39.4 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 23/102 (22%), Positives = 41/102 (40%), Gaps = 5/102 (4%) Query: 371 NSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMA 430 NS++ L L G+ +EAI + R+A+ L P + L EA+ Sbjct: 3 NSIKTLSNLANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLANLLAQEGKAEEAI--- 59 Query: 431 NNVYKTLGANAQTLTLLAT--VCLEDPVTQEKAKTLLDKALT 470 + K + + + L+ V L E+A + KA++ Sbjct: 60 KYMRKAVSLDPNNIKTLSNLAVLLAQEGKAEEAIKYMRKAVS 101 Score = 33.6 bits (75), Expect = 0.23, Method: Composition-based stats. Identities = 24/89 (26%), Positives = 42/89 (47%), Gaps = 1/89 (1%) Query: 451 CLEDPVTQEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCV 510 L E+A + KA++ P+ IK + A LL++E K E+ I +R A++ + + Sbjct: 14 LLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLANLLAQEGKAEEAIKYMRKAVSLDPNNI 73 Query: 511 LHRI-LGDFLVAVNEYQEAMDQYSIALSL 538 L L + +EA+ A+SL Sbjct: 74 KTLSNLAVLLAQEGKAEEAIKYMRKAVSL 102 Score = 32.8 bits (73), Expect = 0.46, Method: Composition-based stats. Identities = 16/89 (17%), Positives = 38/89 (42%), Gaps = 6/89 (6%) Query: 468 ALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQE 527 ++ + + ++ + + ++L N + S+ L + L + +E Sbjct: 4 SIKTLSNLANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSN------LANLLAQEGKAEE 57 Query: 528 AMDQYSIALSLDPNDQKSLEGMQKMEKEE 556 A+ A+SLDPN+ K+L + + +E Sbjct: 58 AIKYMRKAVSLDPNNIKTLSNLAVLLAQE 86 >2C2L-A nrPDB Length = 281 Score = 44.0 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 18/86 (20%), Positives = 31/86 (36%) Query: 350 FYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDC 409 F ++Y A +AI N + M + ++A+ R A+ L + Sbjct: 15 FVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQPEQALADCRRALELDGQSVKA 74 Query: 410 YEGLIECYLASNSIREAMVMANNVYK 435 + L +C L S EA+ Y Sbjct: 75 HFFLGQCQLEMESYDEAIANLQRAYS 100 Score = 29.7 bits (65), Expect = 4.0, Method: Composition-based stats. Identities = 15/55 (27%), Positives = 25/55 (45%) Query: 350 FYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAP 404 ++ +AL +A++L+ SV+A G M EAI + + A LA Sbjct: 49 LKMQQPEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSLAK 103 >2GW1-A nrPDB Length = 514 Score = 44.0 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 33/151 (21%), Positives = 61/151 (40%), Gaps = 7/151 (4%) Query: 392 AIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVC 451 A ++AI L P ++ Y + N E N K L ++ ++ Sbjct: 256 AHEDIKKAIELFPR-VNSYIYMALIMADRNDSTE---YYNYFDKALKLDSNNSSVYYHRG 311 Query: 452 LEDPVTQ--EKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDC 509 + + Q ++A DKA P+ I ++ A L RE K++D L A + Sbjct: 312 QMNFILQNYDQAGKDFDKAKELDPENIFPYIQLACLAYRENKFDDCETLFSEAKRKFPEA 371 Query: 510 -VLHRILGDFLVAVNEYQEAMDQYSIALSLD 539 + + L N++ +A+ QY +A+ L+ Sbjct: 372 PEVPNFFAEILTDKNDFDKALKQYDLAIELE 402 Score = 40.1 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 36/170 (21%), Positives = 55/170 (32%), Gaps = 15/170 (8%) Query: 269 DNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLG 328 +N + + F + + F++A+ LDP I L RE + +D E L Sbjct: 302 NNSSVYYHRGQMNFILQNYDQAGKDFDKAKELDPENIFPYIQLACLAYRENKFDDCETL- 360 Query: 329 CRLFNISDQHAEPWVVSGCHS---FYSKRYSRALYLGAKAI----QLNSNSVQALLLKGA 381 + E V + + +AL AI +L+ V L G Sbjct: 361 --FSEAKRKFPEAPEVPNFFAEILTDKNDFDKALKQYDLAIELENKLDGIYVGIAPLVGK 418 Query: 382 ALRNM-----GRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREA 426 A EA +A +L P GL + L I EA Sbjct: 419 ATLLTRNPTVENFIEATNLLEKASKLDPRSEQAKIGLAQMKLQQEDIDEA 468 Score = 33.6 bits (75), Expect = 0.29, Method: Composition-based stats. Identities = 14/78 (17%), Positives = 29/78 (37%), Gaps = 1/78 (1%) Query: 350 FYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDC 409 F +K+Y A+ A++L + V A ++G +++ + +A+ L P Sbjct: 17 FRNKKYDDAIKYYNWALELKEDPVF-YSNLSACYVSVGDLKKVVEMSTKALELKPDYSKV 75 Query: 410 YEGLIECYLASNSIREAM 427 +AM Sbjct: 76 LLRRASANEGLGKFADAM 93 Score = 30.1 bits (66), Expect = 3.1, Method: Composition-based stats. Identities = 20/137 (14%), Positives = 47/137 (34%), Gaps = 8/137 (5%) Query: 333 NISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEA 392 + ++ P++ C ++ ++ L ++A + + + L + +A Sbjct: 332 ELDPENIFPYIQLACLAYRENKFDDCETLFSEAKRKFPEAPEVPNFFAEILTDKNDFDKA 391 Query: 393 IIHFREAIRLAPCRLDCYEGLI-----ECYLASNSIREAMVMANN-VYKTLGANAQTLTL 446 + + AI L Y G+ L N E + A N + K + ++ Sbjct: 392 LKQYDLAIELENKLDGIYVGIAPLVGKATLLTRNPTVENFIEATNLLEKASKLDPRSE-- 449 Query: 447 LATVCLEDPVTQEKAKT 463 A + L Q++ Sbjct: 450 QAKIGLAQMKLQQEDID 466 >1A17-A nrPDB Length = 166 Score = 43.2 bits (100), Expect = 4e-04, Method: Composition-based stats. Identities = 19/86 (22%), Positives = 31/86 (36%) Query: 350 FYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDC 409 F +K Y A+ ++AI+LN ++ + A A+ AI L + Sbjct: 24 FKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKG 83 Query: 410 YEGLIECYLASNSIREAMVMANNVYK 435 Y +A R A+ V K Sbjct: 84 YYRRAASNMALGKFRAALRDYETVVK 109 Score = 36.3 bits (82), Expect = 0.041, Method: Composition-based stats. Identities = 24/163 (14%), Positives = 58/163 (35%), Gaps = 36/163 (22%) Query: 278 ADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQ 337 A+ YF+A D +N++ + QA L+P + Sbjct: 20 ANDYFKAKDYENAIKFYSQAIELNP---------SNAIYY------------------GN 52 Query: 338 HAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFR 397 + ++ + C+ + AL +AI+L+ ++ + A+ +G+ + A+ + Sbjct: 53 RSLAYLRTECYGY-------ALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYE 105 Query: 398 EAIRLAPCRLDCYEGLIEC--YLASNSIREAMVMANNVYKTLG 438 +++ P D EC + + A+ + + Sbjct: 106 TVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVD 148 >5ZYQ-A nrPDB Length = 320 Score = 42.8 bits (99), Expect = 5e-04, Method: Composition-based stats. Identities = 20/87 (22%), Positives = 34/87 (39%), Gaps = 1/87 (1%) Query: 329 CRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNS-VQALLLKGAALRNMG 387 + N S + + C SF K Y AL KA++ N + L G + Sbjct: 153 HFVLNQSPNNIPALLGKACISFNKKDYRGALAYYKKALRTNPGCPAEVRLGMGHCFVKLN 212 Query: 388 RVQEAIIHFREAIRLAPCRLDCYEGLI 414 ++++A + F A+ L + GL Sbjct: 213 KLEKARLAFSRALELNSKCVGALVGLA 239 Score = 38.2 bits (87), Expect = 0.011, Method: Composition-based stats. Identities = 20/111 (18%), Positives = 48/111 (43%), Gaps = 4/111 (3%) Query: 350 FYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAP-CRLD 408 + +A + + N++ ALL K N + A+ ++++A+R P C + Sbjct: 140 LEGDKMDQADAQFHFVLNQSPNNIPALLGKACISFNKKDYRGALAYYKKALRTNPGCPAE 199 Query: 409 CYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQE 459 G+ C++ N + +A + + L N++ + L + + + +E Sbjct: 200 VRLGMGHCFVKLNKLEKARLA---FSRALELNSKCVGALVGLAVLELNNKE 247 >4ABN-A nrPDB Length = 474 Score = 40.1 bits (92), Expect = 0.003, Method: Composition-based stats. Identities = 27/140 (19%), Positives = 43/140 (30%), Gaps = 22/140 (15%) Query: 261 LEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGR 320 L+K L D + D YF +++ K + Q ++ M+ E + Sbjct: 47 LQKLQGLVDRLYCF---RDSYFETHSVEDAGRKQQDVQEEMEKTLQQMEEVLGSAQVEAQ 103 Query: 321 LEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKG 380 + G L D E V+ KA++L V+A G Sbjct: 104 --ALMLKGKALNVTPDYSPEAEVLLS-----------------KAVKLEPELVEAWNQLG 144 Query: 381 AALRNMGRVQEAIIHFREAI 400 G V A F A+ Sbjct: 145 EVYWKKGDVTSAHTCFSGAL 164 >6AF0-A nrPDB Length = 939 Score = 39.7 bits (91), Expect = 0.004, Method: Composition-based stats. Identities = 45/349 (12%), Positives = 93/349 (26%), Gaps = 88/349 (25%) Query: 264 KSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLED 323 K L + +L +LA LY + ++ +Q + L+ I + Sbjct: 466 KRNLSPDAAVLLNLARLY-ESESPDKALQCLQQVEQLEIDQIPQSEYPPDAEDEAAARAA 524 Query: 324 VENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQ-------------LNS 370 + L + GC ++ A A+ +++ Sbjct: 525 IRKL---------LPPQLLNNIGCFYSQEGKHRLATEFFQAALDSCARISQTENDLDIDA 575 Query: 371 NSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMA 430 G + G + +AI + + + D L L N +E Sbjct: 576 LLTTIPFNLGRSYEYEGDIDKAIETYEQLLSRHSDYTDARTRLAYIKLRRNPNKEG---P 632 Query: 431 NNVYKTLGANAQTLTLLA------------------------------------------ 448 + V K N L + Sbjct: 633 DAVAKLYQENPSDLEVRGLYGWFLSKVNSKKRPANIAEDPEQRHYKHTLQSYDKHDRYAL 692 Query: 449 ------TVCLEDPVTQE------KAKTLLDKALT-------QRPDYIKAVVKKAELLSRE 489 + + +E K ++A+ P A A L + Sbjct: 693 VGMGNLHLMAAREMRRETEQDRQKRSAAYNRAVEFFDKALQLDPKNAYAAQGIAIALVED 752 Query: 490 QK-YEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALS 537 +K Y++ + + D ++ +G + ++ +A++ Y IALS Sbjct: 753 RKDYKNALQIFIKVRETIQDAHVYVNMGHIYAELRQFSKAIESYEIALS 801 >4I9E-A nrPDB Length = 383 Score = 39.4 bits (90), Expect = 0.005, Method: Composition-based stats. Identities = 43/289 (14%), Positives = 88/289 (30%), Gaps = 52/289 (17%) Query: 276 SLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAR------EGRLEDVENLGC 329 S+ D + + K + + E+ Q L Y M+ L+ + R+E+ L Sbjct: 27 SIPDAEYLRREIKQELDQMEEDQDLHLY-YSLMEFRHNLMLEYLEPLEKMRIEEQPRLSD 85 Query: 330 RLFNISDQHAEPWVVS--------GCHSFYSKRYSRALYLGAKA------IQLNSNSVQA 375 L I + A + G + + Y A+ KA ++ + Sbjct: 86 LLLEIDKKQARLTGLLEYYFNFFRGMYELDQREYLSAIKFFKKAESKLIFVKDRIEKAEF 145 Query: 376 LLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIEC--YLASN--SIREAMVMAN 431 + M + ++ + R+A + L++C A+N +++ + Sbjct: 146 FFKMSESYYYMKQTYFSMDYARQAYEIYKEHEAYNIRLLQCHSLFATNFLDLKQYEDAIS 205 Query: 432 NVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVVKKAELLSREQK 491 + K EK L+ + L + +++ Sbjct: 206 HFQKAY----------------SMAEAEKQPQLMGRTLY---NIGLCKNSQSQYEDAIPY 246 Query: 492 YEDGIA--LLRNALANQSDCV-----LHRILGDFLVAVNEYQEAMDQYS 533 ++ IA N L + +H LG +EY YS Sbjct: 247 FKRAIAVFEESNILPSLPQAYFLITQIHYKLGKI-DKAHEYHSKGMAYS 294 >1QZ2-A nrPDB Length = 336 Score = 39.0 bits (89), Expect = 0.007, Method: Composition-based stats. Identities = 28/183 (15%), Positives = 56/183 (30%), Gaps = 15/183 (8%) Query: 414 IECYLASNSIREAMVMANNVYKTLGA----------NAQTLTLLATV----CLEDPVTQE 459 Y ++A++ + L AQ L L + + C Sbjct: 154 GTVYFKEGKYKQALLQYKKIVSWLEYESSFSNEEAQKAQALRLASHLNLAMCHLKLQAFS 213 Query: 460 KAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFL 519 A +KAL + K + ++ E +E A + L + + Sbjct: 214 AAIESCNKALELDSNNEKGLFRRGEAHLAVNDFELARADFQKVLQLYPNNKAAKTQLAVC 273 Query: 520 VAVNEYQEAMDQYSIALSLDPNDQKSLEGMQKMEKEESPTDA-TQEEDVDDMEGSGEEGD 578 Q A ++ A + ++ + + + PTD +EE + GS + + Sbjct: 274 QQRIRRQLAREKKLYANMFERLAEEENKAKAEASSGDHPTDTEMKEEQKSNTAGSQSQVE 333 Query: 579 LEG 581 E Sbjct: 334 TEA 336 Score = 30.5 bits (67), Expect = 2.0, Method: Composition-based stats. Identities = 17/128 (13%), Positives = 36/128 (28%), Gaps = 9/128 (7%) Query: 363 AKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNS 422 +A + + + + L + AI +A+ L E +LA N Sbjct: 186 EEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVND 245 Query: 423 IREAMVMANNVYKTLGANAQTLTLLATVCL------EDPVTQEKAKTLLDKALTQRPDYI 476 A + K L + + ++K + + L + + Sbjct: 246 FELA---RADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMFERLAEEENKA 302 Query: 477 KAVVKKAE 484 KA + Sbjct: 303 KAEASSGD 310 >5OQL-E nrPDB Length = 414 Score = 38.6 bits (88), Expect = 0.008, Method: Composition-based stats. Identities = 20/102 (19%), Positives = 33/102 (32%) Query: 338 HAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFR 397 E W+ + K R + +A++L+ + L G G +Q A HF Sbjct: 106 SIELWLAYLEFAAQVKATKRWRRIMTRALRLHPMNASLWTLAGRRAAQNGDMQRARAHFL 165 Query: 398 EAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGA 439 R + C + + EA V K + A Sbjct: 166 RGCRFCTREPTLWLEYARCEMDWLARMEAKKQGQGVRKGVNA 207 >5IC8-A nrPDB Length = 334 Score = 38.6 bits (88), Expect = 0.008, Method: Composition-based stats. Identities = 20/102 (19%), Positives = 33/102 (32%) Query: 338 HAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFR 397 E W+ + K R + +A++L+ + L G G +Q A HF Sbjct: 26 SIELWLAYLEFAAQVKATKRWRRIMTRALRLHPMNASLWTLAGRRAAQNGDMQRARAHFL 85 Query: 398 EAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGA 439 R + C + + EA V K + A Sbjct: 86 RGCRFCTREPTLWLEYARCEMDWLARMEAKKQGQGVRKGVNA 127 >4HOQ-A nrPDB Length = 482 Score = 37.4 bits (85), Expect = 0.017, Method: Composition-based stats. Identities = 23/154 (14%), Positives = 47/154 (30%), Gaps = 15/154 (9%) Query: 356 SRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLA------PCRLDC 409 S A++ A++ +S A G+ A FR+A+RL ++ Sbjct: 321 SSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENITDDHKHQIHY 380 Query: 410 YEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKAL 469 + G + + + ++ + L ++ L T + + AL Sbjct: 381 HYGRFQEFHRKSE----NTAIHHYLEALKVKDRSP--LRTKLTSALKKLSTKRLCHN-AL 433 Query: 470 TQRPDYIKAVVKK--AELLSREQKYEDGIALLRN 501 + V K E + YE + Sbjct: 434 DVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPE 467 Score = 29.7 bits (65), Expect = 3.9, Method: Composition-based stats. Identities = 23/122 (18%), Positives = 36/122 (29%), Gaps = 22/122 (18%) Query: 376 LLLKGAALRNMGRVQEAIIHFREAIRL---------APCRLDCYEGLIECYLASNSIREA 426 L G+ ++A+ +A + L + Y + + EA Sbjct: 54 YNLLAYVKHLKGQNKDALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEA 113 Query: 427 MV---MANNVYKTLGANAQTLTLLA--TVCLEDPVTQ-------EKAKTLLDKALTQRPD 474 NV K L + L T C + +KAK +KAL PD Sbjct: 114 QKYTGKIGNVCKKLS-SPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPD 172 Query: 475 YI 476 Sbjct: 173 NP 174 >5DSE-A nrPDB Length = 837 Score = 37.0 bits (84), Expect = 0.023, Method: Composition-based stats. Identities = 49/250 (19%), Positives = 85/250 (34%), Gaps = 28/250 (11%) Query: 301 DPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRY----S 356 DP KG + Y L R R+ G +F + E ++ + R Sbjct: 287 DPLR-KGANTKTYTLTRRARV----YSGENIFCPQENTEEALLLLLISESMANRDAVLSR 341 Query: 357 RALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIEC 416 + + I L S SV L AL G+ + A++ A + Sbjct: 342 IPEHKSDRLISLQSASV-VYDLLTIALGRRGQYEMLSECLERAMKFAFEEFHLWYQFALS 400 Query: 417 YLASNSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYI 476 +A+ A+ + + +A L A +C+ E+A+ + Sbjct: 401 LMAAGKSARAVKVLKECIRLKPDDATIPLLAAKLCMGSLHWLEEAE-----------KFA 449 Query: 477 KAVVKKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIAL 536 K VV E + E K + +AL +D L R + + L +A+ + A Sbjct: 450 KTVVDVGEK-TSEFKAKGYLALGLTYSLQATDASL-RGMQEVLQR-----KALLAFQRAH 502 Query: 537 SLDPNDQKSL 546 SL P D ++ Sbjct: 503 SLSPTDHQAA 512 Score = 36.3 bits (82), Expect = 0.035, Method: Composition-based stats. Identities = 40/190 (21%), Positives = 70/190 (36%), Gaps = 39/190 (20%) Query: 217 AEVAS-MTMNVIQTVPNLDWLSV---WIKAYAFVHTGDNSRAISTICSLEKKSLLRDNVD 272 +EVAS + + + P W+++ W+ A A V+ G A +T C+ E +L + + Sbjct: 667 SEVASSLQSSAPKQGPLHPWMTLAQIWLHA-AEVYIGIGKPAEATACTQEAANLFPMSHN 725 Query: 273 LLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLF 332 +L + G + +E+A + P +K M +L + G Sbjct: 726 VLYMRGQIAELRGSMDEARRWYEEALAISPTHVKSMQRLALILHQLG------------- 772 Query: 333 NISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEA 392 RYS A + A+Q+NS + + G L+ G A Sbjct: 773 ---------------------RYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAA 811 Query: 393 IIHFREAIRL 402 F A+ L Sbjct: 812 TECFLTALEL 821 Score = 34.0 bits (76), Expect = 0.19, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 28/67 (41%) Query: 356 SRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIE 415 A +A+ ++ V+++ L +GR A R+A+++ + + GL E Sbjct: 741 DEARRWYEEALAISPTHVKSMQRLALILHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGE 800 Query: 416 CYLASNS 422 A + Sbjct: 801 VLQAQGN 807 >2Y4T-A nrPDB Length = 450 Score = 36.7 bits (83), Expect = 0.032, Method: Composition-based stats. Identities = 48/222 (21%), Positives = 83/222 (37%), Gaps = 35/222 (15%) Query: 240 IKAYAFVHTGDNSRAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQM 299 ++A F+ G+ +AIS + + K DN + ++ LY++ GD++ S+ + + Sbjct: 182 LRAECFIKEGEPRKAISDLKAASKLKN--DNTEAFYKISTLYYQLGDHELSLSEVRECLK 239 Query: 300 LD----------------PYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWV 343 LD LI+ + L R+GR D + + AE V Sbjct: 240 LDQDHKRCFAHYKQVKKLNKLIESAEE----LIRDGRYTDATSKYESVMKTEPSIAEYTV 295 Query: 344 VSG---CHSFYSKRYSR-ALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREA 399 S CH F A+ + ++ +Q+ ++V AL + A EAI + A Sbjct: 296 RSKERICHCFSKDEKPVEAIRVCSEVLQMEPDNVNALKDRAEAYLIEEMYDEAIQDYETA 355 Query: 400 IRLAPCRLDCYEGL--IECYLASNSIREAMVMANNVYKTLGA 439 EGL + L + + YK LG Sbjct: 356 QEHNENDQQIREGLEKAQRLLKQS-------QKRDYYKILGV 390 Score = 35.9 bits (81), Expect = 0.045, Method: Composition-based stats. Identities = 48/241 (19%), Positives = 88/241 (36%), Gaps = 34/241 (14%) Query: 356 SRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIE 415 AL K IQL + A L +G L G++ EA F++ ++ P + E + Sbjct: 77 KAALPDLTKVIQLKMDFTAARLQRGHLLLKQGKLDEAEDDFKKVLKSNPSENEEKEAQSQ 136 Query: 416 CYLASNSIREAMVMANNVYKTLGANAQTLTL--LATVCLEDPVTQE-------------K 460 + S+ ++ A N + + A L + VC+ D +E K Sbjct: 137 -LIKSDEMQRLRSQALNAFGSGDYTAAIAFLDKILEVCVWDAELRELRAECFIKEGEPRK 195 Query: 461 AKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSD---CVLHRILGD 517 A + L A + D +A K + L + +E ++ +R L D C H Sbjct: 196 AISDLKAASKLKNDNTEAFYKISTLYYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQVK 255 Query: 518 FLVAV----------NEYQEAMDQYSIALSLDPNDQKSLEGMQK-----MEKEESPTDAT 562 L + Y +A +Y + +P+ + ++ K+E P +A Sbjct: 256 KLNKLIESAEELIRDGRYTDATSKYESVMKTEPSIAEYTVRSKERICHCFSKDEKPVEAI 315 Query: 563 Q 563 + Sbjct: 316 R 316 Score = 33.6 bits (75), Expect = 0.25, Method: Composition-based stats. Identities = 39/261 (14%), Positives = 90/261 (34%), Gaps = 23/261 (8%) Query: 349 SFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLD 408 +F S Y+ A+ K +++ + L+ G ++AI + A +L + Sbjct: 153 AFGSGDYTAAIAFLDKILEVCVWDAELRELRAECFIKEGEPRKAISDLKAASKLKNDNTE 212 Query: 409 CYEGLIECYLASNS--IREAMVMA------------NNVYKTLGANAQTLTLLATVCLED 454 + + Y + + V + + N + + L Sbjct: 213 AFYKISTLYYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNK---LIESAEELIR 269 Query: 455 PVTQEKAKTLLDKALTQRPDYIKAVVKKAE----LLSREQKYEDGIALLRNALANQSDCV 510 A + + + P + V+ E S+++K + I + L + D V Sbjct: 270 DGRYTDATSKYESVMKTEPSIAEYTVRSKERICHCFSKDEKPVEAIRVCSEVLQMEPDNV 329 Query: 511 -LHRILGDFLVAVNEYQEAMDQYSIALSLDPNDQKSLEGMQKMEKEESPTDATQEEDVDD 569 + + + Y EA+ Y A + NDQ+ EG++K ++ + + Sbjct: 330 NALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQQIREGLEKAQRLLKQSQKRDYYKILG 389 Query: 570 ME-GSGEEGDLEGSDSEAAQW 589 ++ + ++ ++ A QW Sbjct: 390 VKRNAKKQEIIKAYRKLALQW 410 >4G1T-A nrPDB Length = 472 Score = 36.7 bits (83), Expect = 0.033, Method: Composition-based stats. Identities = 25/141 (17%), Positives = 56/141 (39%), Gaps = 7/141 (4%) Query: 388 RVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLL 447 + + A + F +A+ P + GL ++ + + + + + N L Sbjct: 153 QNERAKVCFEKALEKKPKNPEFTSGLAIASYRLDNWPPSQNAIDPLRQAIRLNPDNQYLK 212 Query: 448 ATVCLEDPVTQEKAKT------LLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRN 501 + L+ +E+ + L+++AL + P + A+ R+ + + I LL+ Sbjct: 213 VLLALKLHKMREEGEEEGEGEKLVEEALEKAPGVTDVLRSAAKFYRRKDEPDKAIELLKK 272 Query: 502 ALAN-QSDCVLHRILGDFLVA 521 AL ++ LH +G A Sbjct: 273 ALEYIPNNAYLHCQIGCCYRA 293 >4UZY-A nrPDB Length = 651 Score = 35.5 bits (80), Expect = 0.065, Method: Composition-based stats. Identities = 33/203 (16%), Positives = 65/203 (32%), Gaps = 33/203 (16%) Query: 313 YLLAREGR-LEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNS- 370 Y L +E + E +++L +L N+ + A ++ C+ +Y+ +Y A + + + L Sbjct: 25 YTLIKEQKFAEAIQHLQYQLQNVPESRAALSLLGYCY-YYTGQYDMASQMYEQLVTLYPS 83 Query: 371 ----NSVQALLL-KGAALRNMGRV-------QEAII---------------HFREAIRLA 403 A L KG + Q+A+ R+ + A Sbjct: 84 NEDYKLYYAQSLYKGGMYPEASKAVVKVEGHQKAVTTLLVACSYEQDDLTGCRRQLDKCA 143 Query: 404 PCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTL--TLLATVCLEDPVTQEKA 461 P D A N+ + LG + L L + K Sbjct: 144 PEDPDTMVNTGCIMFKEGKFEAARQKFNDAVQALGYQPELLYNIALCYYKTKQFGPALKH 203 Query: 462 KT-LLDKALTQRPDYIKAVVKKA 483 +++KA+ + P+ Sbjct: 204 LAEIIEKAVREHPELSVGSNTDG 226 Score = 31.3 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 24/180 (13%), Positives = 56/180 (31%), Gaps = 11/180 (6%) Query: 357 RALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIEC 416 ++ + + + L + EAI H + ++ P L C Sbjct: 3 ASMAFFQQPAR--PIAEGQYTQTIYTLIKEQKFAEAIQHLQYQLQNVPESRAALSLLGYC 60 Query: 417 YLASNSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLL-----DKALTQ 471 Y + A M + +N A + + E +K ++ KA+T Sbjct: 61 YYYTGQYDMASQMYEQLVTLYPSNEDYKLYYAQSLYKGGMYPEASKAVVKVEGHQKAVTT 120 Query: 472 RPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQ 531 + ++ +L ++ + + + N + G F A ++ +A+ Sbjct: 121 L--LVACSYEQDDLTGCRRQLDKCAPEDPDTMVNTG--CIMFKEGKFEAARQKFNDAVQA 176 >4JHR-A nrPDB Length = 333 Score = 35.5 bits (80), Expect = 0.069, Method: Composition-based stats. Identities = 30/210 (14%), Positives = 63/210 (30%), Gaps = 44/210 (20%) Query: 373 VQALLLKGAALRNMGRVQEAIIHFREAIRLAPC------RLDCYEGLIECYLASNSI--- 423 +A G L+ +G EAI+ + + ++ L Y A Sbjct: 11 AKASGNLGNTLKVLGNFDEAIVCCQRHLDISRELNDKVGEARALYNLGNVYHAKGKSFGC 70 Query: 424 -------REAMVMANNVYKTLGANAQTLTLLATVC------------------------- 451 + N + + + L+L+ + Sbjct: 71 PGPQDTGEFPEDVRNALQAAVDLYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDA 130 Query: 452 -LEDPVTQEKAKTLLDKALTQR--PDYIKAVVKKAELLSREQKYEDGIALLRNALANQSD 508 + AK DKA +R + A + E + + Y+ + L R + Sbjct: 131 VIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRAVE 190 Query: 509 CVLHRILGDFLVAVNEYQEAMDQYSIALSL 538 LG+ + +Y++A+D + L++ Sbjct: 191 AQSCYSLGNTYTLLQDYEKAIDYHLKHLAI 220 Score = 32.4 bits (72), Expect = 0.52, Method: Composition-based stats. Identities = 17/90 (18%), Positives = 32/90 (35%), Gaps = 9/90 (10%) Query: 351 YSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCY 410 + +R A G KA + +A G A +G + A ++++ + LA D Sbjct: 134 HEQRLLIAKEFGDKAAER-----RAYSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRA 188 Query: 411 EGLIECYLASNSIREAMVMANNVYKTLGAN 440 CY N+ + K + + Sbjct: 189 VEAQSCYSLGNTYTL----LQDYEKAIDYH 214 >2IF4-A nrPDB Length = 338 Score = 34.7 bits (78), Expect = 0.12, Method: Composition-based stats. Identities = 26/198 (13%), Positives = 58/198 (29%), Gaps = 51/198 (25%) Query: 380 GAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGA 439 G +L +++EA+ + AI + + Y + A+ ++ Sbjct: 186 GNSLFKEEKLEEAMQQYEMAIAYMGDDF-----MFQLYGKYQDMALAVKNPCHLNIA--- 237 Query: 440 NAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALL 499 CL ++A + LT+ KA+ ++ Sbjct: 238 ----------ACLIKLKRYDEAIGHCNIVLTEEEKNPKALFRR----------------- 270 Query: 500 RNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDPNDQKSLEGMQKMEKEESPT 559 G + + A D + A P+D+ ++ + ++E Sbjct: 271 ----------------GKAKAELGQMDSARDDFRKAQKYAPDDKAIRRELRALAEQEKAL 314 Query: 560 DATQEEDVDDMEGSGEEG 577 Q+E + +EG Sbjct: 315 YQKQKEMYKGIFKGKDEG 332 >5JZ6-A nrPDB Length = 429 Score = 34.7 bits (78), Expect = 0.12, Method: Composition-based stats. Identities = 32/152 (21%), Positives = 58/152 (38%), Gaps = 21/152 (13%) Query: 167 RTPKINMMLANLYKKAGQERPSVTSYKEVLRQCPLALDAILGL------LSLSVKGAEVA 220 +T K + A +K G+ +V ++KE++R+ P + A G L+ + EV Sbjct: 10 KTIKAELDAAEKLRKRGKIEEAVNAFKELVRKYPQSPRARYGKAQCEDDLAEKRRSNEVL 69 Query: 221 SMTMNVIQTVPNL-----DWLSVWIK-----AYAFVHTGDNSRAISTICSLEKKSLLRDN 270 + Q V +L D L + +K H + + + L ++ Sbjct: 70 RGAIETYQEVASLPDVPADLLKLSLKRRSDRQQFLGHMRGSLLTLQRLV-----QLFPND 124 Query: 271 VDLLGSLADLYFRAGDNKNSVLKFEQAQMLDP 302 L L Y GDN N+ +E+ + P Sbjct: 125 TSLKNDLGVGYLLIGDNDNAKKVYEEVLSVTP 156 >5NNP-A nrPDB Length = 745 Score = 34.7 bits (78), Expect = 0.13, Method: Composition-based stats. Identities = 19/83 (22%), Positives = 36/83 (43%), Gaps = 1/83 (1%) Query: 459 EKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCVL-HRILGD 517 ++ ++ L + P + + KA +L+ + K E+ AL + AL + + G Sbjct: 27 KRGLKAAEQILKKNPKHGDTMSMKALILNAQGKTEEAFALAKEALTIDMKSYICWHVYGI 86 Query: 518 FLVAVNEYQEAMDQYSIALSLDP 540 + EA+ Y AL L+P Sbjct: 87 LYRTNKNFDEAIKAYKFALKLEP 109 Score = 34.3 bits (77), Expect = 0.16, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 29/65 (44%) Query: 342 WVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIR 401 ++ + + S+ +RAL KAI+L+ +V + K ++ G + +A A Sbjct: 377 YLAQHYNYYMSRDLTRALEYVEKAIELDPKNVDFHMTKARIFKHQGDLAKAAETMDYARS 436 Query: 402 LAPCR 406 L P Sbjct: 437 LDPKD 441 Score = 29.0 bits (63), Expect = 6.9, Method: Composition-based stats. Identities = 16/59 (27%), Positives = 24/59 (40%) Query: 378 LKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKT 436 L+ + L + R EA +R + P +D Y+GLI S EA + Y Sbjct: 227 LRASYLSKLARKDEAAKAYRALLDRNPEHMDYYKGLISALDISADDEEAQKAVYDEYAA 285 >6FRK-r nrPDB Length = 605 Score = 34.3 bits (77), Expect = 0.15, Method: Composition-based stats. Identities = 34/198 (17%), Positives = 56/198 (28%), Gaps = 22/198 (11%) Query: 346 GCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPC 405 + R AL A Q + G L + R E + +R+ +R + Sbjct: 85 AYCEYRLNRIENALKTIESANQQTDKLKELY---GQVLYRLERYDECLAVYRDLVRNSQD 141 Query: 406 RLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLL 465 D + + V+ N+ L L A L +A +L Sbjct: 142 DYDEERKTNLSAVVAAQSNWEKVVPENL--GLQEGTHELCYNAACALIGQGQLSQAMKIL 199 Query: 466 DKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVAVNEY 525 KA +E DG A ++H + L Sbjct: 200 QKAED------LCRRSLSE-------DSDGTEEDPQA----ELAIIHGQMAYILQLQGRT 242 Query: 526 QEAMDQYSIALSLDPNDQ 543 +EA+ Y+ + L P D Sbjct: 243 EEALQLYNQIIKLKPTDV 260 Score = 30.5 bits (67), Expect = 2.3, Method: Composition-based stats. Identities = 49/304 (16%), Positives = 98/304 (32%), Gaps = 61/304 (20%) Query: 242 AYAFVHTGDNSRAISTICSLEKKSLLRDNVDLLGSL-ADLYFRAGDNKNSVLKFEQAQM- 299 + +F R +L+ D L L + +R + + Sbjct: 79 SLSFEKAYCEYRLNRIENALKTIESANQQTDKLKELYGQVLYRLERYDECLAVYRDLVRN 138 Query: 300 -LDPYLIKGMDVYGYLLAREGRLEDV--ENLGCRLFNISDQHAEPWVVSGCHSFYSKRYS 356 D Y + ++A + E V ENLG + + E + C + S Sbjct: 139 SQDDYDEERKTNLSAVVAAQSNWEKVVPENLG-----LQEGTHELCYNAACALIGQGQLS 193 Query: 357 RALYLGAKA--------------IQLNSNSVQALL--LKGAALRNMGRVQEAIIHFREAI 400 +A+ + KA + + + A++ L+ GR +EA+ + + I Sbjct: 194 QAMKILQKAEDLCRRSLSEDSDGTEEDPQAELAIIHGQMAYILQLQGRTEEALQLYNQII 253 Query: 401 RLAPCRLDCYEGLIECYLASN----------------------SIREAMVMANNVYKTLG 438 +L P + + + N + + + A K L Sbjct: 254 KLKPTDVGLLAVIANNIITINKDQNVFDSKKKVKLTNAEGVEFKLSKKQLQAIEFNKALL 313 Query: 439 ANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIAL 498 A T A C + + + +Q P+++ V+ +A L RE+++ I L Sbjct: 314 A---MYTNQAEQCRKISASLQ----------SQSPEHLLPVLIQAAQLCREKQHTKAIEL 360 Query: 499 LRNA 502 L+ Sbjct: 361 LQEF 364 >5OJF-A nrPDB Length = 314 Score = 34.0 bits (76), Expect = 0.19, Method: Composition-based stats. Identities = 25/160 (15%), Positives = 50/160 (31%), Gaps = 23/160 (14%) Query: 369 NSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLA--------PCRLDCYEGLIECYLAS 420 + + L + R+ + ++A +A+ + P L Y Sbjct: 66 HPDVATMLNILALVYRDQNKYKDAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKR 125 Query: 421 NSIREAMVMANNV----YKTLG-ANAQTLTLLATVCL--EDPVTQEKAKTLLDKALTQ-- 471 +EA + K LG + L+ + L ++ E+ + +AL Sbjct: 126 GKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYA 185 Query: 472 ------RPDYIKAVVKKAELLSREQKYEDGIALLRNALAN 505 P+ K A ++ KY+D L + L Sbjct: 186 TRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTR 225 >5JHE-A nrPDB Length = 397 Score = 33.6 bits (75), Expect = 0.25, Method: Composition-based stats. Identities = 22/145 (15%), Positives = 51/145 (35%), Gaps = 24/145 (16%) Query: 268 RDNVDLLGSLADLYFRAGDNKNSVLKFEQ-AQMLDPYLIK-GMDVYGYLLAREGRLEDVE 325 + +++ L F+ D N+ K+ + ++ Y+ + +D + +++ Sbjct: 241 LEAANIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFINLKMKIYL 300 Query: 326 NLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLN--SN--SVQALLLKGA 381 NL LFN+ RY A+ ++++ N +A +G Sbjct: 301 NLSLVLFNLE------------------RYDDAIMYATYLLEMDNVPNRDQAKAYYRRGN 342 Query: 382 ALRNMGRVQEAIIHFREAIRLAPCR 406 + R+ EA+ + P Sbjct: 343 SYLKKKRLDEALQDYIFCKEKNPDD 367 >3ZFW-A nrPDB Length = 263 Score = 33.2 bits (74), Expect = 0.32, Method: Composition-based stats. Identities = 25/160 (15%), Positives = 50/160 (31%), Gaps = 23/160 (14%) Query: 369 NSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLA--------PCRLDCYEGLIECYLAS 420 + + L + R+ + ++A +A+ + P L Y Sbjct: 19 HPDVATMLNILALVYRDQNKYKDAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKR 78 Query: 421 NSIREAMVMANNV----YKTLG-ANAQTLTLLATVCL--EDPVTQEKAKTLLDKALTQ-- 471 +EA + K LG + L+ + L ++ E+ + +AL Sbjct: 79 GKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYA 138 Query: 472 ------RPDYIKAVVKKAELLSREQKYEDGIALLRNALAN 505 P+ K A ++ KY+D L + L Sbjct: 139 TRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTR 178 >6AHD-N nrPDB Length = 941 Score = 33.2 bits (74), Expect = 0.32, Method: Composition-based stats. Identities = 31/225 (13%), Positives = 70/225 (31%), Gaps = 10/225 (4%) Query: 286 DNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVS 345 + + + +A+ P M L + + ++L + + W++ Sbjct: 657 EYERARRLLAKARSSAPTARVFMKSVK-LEWVQDNIRAAQDLCEEALRHYEDFPKLWMMK 715 Query: 346 GCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPC 405 G + +A + ++ +S LL +G++ A ++ P Sbjct: 716 GQIEEQKEMMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPK 775 Query: 406 RLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLAT-VCLED-PVTQEKAKT 463 + + + + + K L + L + + LE P + K+ Sbjct: 776 NPGLWLESVRLEYRAG---LKNIANTLMAKALQECPNSGILWSEAIFLEARPQRRTKSVD 832 Query: 464 LLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSD 508 L K P + AV A+L ++K + SD Sbjct: 833 ALKKC-EHDPHVLLAV---AKLFWSQRKITKAREWFHRTVKIDSD 873 >5MGX-E nrPDB Length = 290 Score = 33.2 bits (74), Expect = 0.35, Method: Composition-based stats. Identities = 27/151 (17%), Positives = 53/151 (35%), Gaps = 19/151 (12%) Query: 414 IECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRP 473 + A + K + ++A+ D +E+A+ L K Sbjct: 138 GNAHYQRADFVLAANSYDLAIKAITSSAK----------VDMTFEEEAQLLQLK------ 181 Query: 474 DYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCV-LHRILGDFLVAVNEYQEAMDQY 532 +K + A + Y + L +Q D + G L EY EA+ Sbjct: 182 --VKCLNNLAASQLKLDHYRAALRSCSLVLEHQPDNIKALFRKGKVLAQQGEYSEAIPIL 239 Query: 533 SIALSLDPNDQKSLEGMQKMEKEESPTDATQ 563 AL L+P+++ + K+ K+ + +T+ Sbjct: 240 RAALKLEPSNKTIHAELSKLVKKHAAQRSTE 270 >5O09-1C nrPDB Length = 238 Score = 32.8 bits (73), Expect = 0.47, Method: Composition-based stats. Identities = 24/186 (12%), Positives = 55/186 (29%), Gaps = 17/186 (9%) Query: 355 YSRALYLGAKAIQLNSNSV-QALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGL 413 Y AL+ + + + + + L GR+ +A + A++++ + E Sbjct: 56 YREALFRAQELRKQDPDLLTGIYSLLAHLYDRWGRMDKAAEFYELALKISAE--NGLEES 113 Query: 414 IECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRP 473 + N++ + G + L + E Sbjct: 114 DKVATIKNNLAMIFKQLRKFERAEGYYCEALETFQRLDGEQSARVASVYN---------- 163 Query: 474 DYIKAVVKKAELLSREQKYEDGIALLRNALANQSD----CVLHRILGDFLVAVNEYQEAM 529 + ++ + +E +A+ +N Q D LG A ++Q+A Sbjct: 164 NLGVLYYSHMDVDRAQVMHERALAIRQNLHEGQMDPADLSQTFINLGAVYKAAGDFQKAE 223 Query: 530 DQYSIA 535 A Sbjct: 224 ACVDRA 229 Score = 32.0 bits (71), Expect = 0.69, Method: Composition-based stats. Identities = 32/217 (14%), Positives = 70/217 (32%), Gaps = 36/217 (16%) Query: 247 HTGDNSRAISTICSLEKKSLLRDNVDL--LGSLADLYFRAGDNKNSVLKF-------EQA 297 SR++ L +R + + LADL + GD + + + ++ Sbjct: 7 QIASASRSVEEARRLAYHDPIRVGALVEQISVLADLRQKEGDFRKAESLYREALFRAQEL 66 Query: 298 QMLDPYLIKGM-DVYGYLLAREGRLE--------DVENLGCRLFNISDQHAEPWVVSGCH 348 + DP L+ G+ + +L R GR++ ++ SD+ A Sbjct: 67 RKQDPDLLTGIYSLLAHLYDRWGRMDKAAEFYELALKISAENGLEESDKVATIKNNLAMI 126 Query: 349 SFYSKRYSRALYLGAKAI--------QLNSNSVQALLLKGAALRNMGRVQEAIIHFREAI 400 +++ RA +A+ + ++ G + V A + A+ Sbjct: 127 FKQLRKFERAEGYYCEALETFQRLDGEQSARVASVYNNLGVLYYSHMDVDRAQVMHERAL 186 Query: 401 RLAPCRLDC----------YEGLIECYLASNSIREAM 427 + + + L Y A+ ++A Sbjct: 187 AIRQNLHEGQMDPADLSQTFINLGAVYKAAGDFQKAE 223 >5OMP-A nrPDB Length = 462 Score = 32.4 bits (72), Expect = 0.50, Method: Composition-based stats. Identities = 24/158 (15%), Positives = 59/158 (37%), Gaps = 19/158 (12%) Query: 268 RDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENL 327 + ++ +YF+ G +V+++ + + +++ L +E + + L Sbjct: 270 LEQAAIVKEKGTVYFKGGKYMQAVIQYGKI-------VSWLEMEYGLSEKESKASESFLL 322 Query: 328 GCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMG 387 L ++ C+ + Y++A+ KA+ L+S + + L +G A M Sbjct: 323 AAFLN-----------LAMCY-LKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMN 370 Query: 388 RVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIRE 425 + A F + + + P + C + E Sbjct: 371 EFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNE 408 >6ICZ-I nrPDB Length = 855 Score = 32.0 bits (71), Expect = 0.75, Method: Composition-based stats. Identities = 51/273 (18%), Positives = 95/273 (34%), Gaps = 24/273 (8%) Query: 273 LLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVY-GYLLAREGRLEDVENLGCRL 331 L SLAD Y R+G + + +E+A + V+ Y E + L Sbjct: 258 LWCSLADYYIRSGHFEKARDVYEEAIRTVMTVRDFTQVFDSYAQFEESMIAAKMETASEL 317 Query: 332 FNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQE 391 + + + F R L L + ++ N + V + + GR +E Sbjct: 318 GREEEDDVD--LELRLARFEQLISRRPLLLNSVLLRQNPHHVHEWHKR--VALHQGRPRE 373 Query: 392 AIIHFREAIR-LAPCRLDC-----YEGLIECYLASNSIREAMVMANNVYKTLGANAQTLT 445 I + EA++ + P + + + Y + + +A V+ + K N + + Sbjct: 374 IINTYTEAVQTVDPFKATGKPHTLWVAFAKFYEDNGQLDDARVI---LEKATKVNFKQVD 430 Query: 446 LLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALAN 505 LA+V E D+AL ++AE Y DG ++N + Sbjct: 431 DLASVWC-QCGELELRHENYDEALRLLRKATALPARRAE-------YFDGSEPVQNRVYK 482 Query: 506 QSDCVLHRILGDFLVAVNEYQEAMDQYSIALSL 538 + +L D ++ +Q Y L L Sbjct: 483 SLK--VWSMLADLEESLGTFQSTKAVYDRILDL 513 >4KPA-A nrPDB Length = 494 Score = 32.0 bits (71), Expect = 0.75, Method: Composition-based stats. Identities = 29/135 (21%), Positives = 52/135 (38%), Gaps = 18/135 (13%) Query: 474 DYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVA---------VNE 524 D +V+K E L+ ++ E + R L C + F V Sbjct: 145 DIAVQLVQKWERLNADEHIEVPEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFITSMVRA 204 Query: 525 YQEAMDQYSIALSLDPNDQKSLEGMQKMEKEESPTDATQEEDVDDMEGSGEEGD------ 578 EAM++ A +P+D E ++ +++ + ++ + D + SGE+ D Sbjct: 205 LDEAMNKLQRA---NPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKASGEQSDDLLTHM 261 Query: 579 LEGSDSEAAQWADQE 593 L G D E + D E Sbjct: 262 LNGKDPETGEPLDDE 276 >4CGU-A nrPDB Length = 112 Score = 32.0 bits (71), Expect = 0.80, Method: Composition-based stats. Identities = 12/58 (20%), Positives = 20/58 (34%) Query: 452 LEDPVTQEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDC 509 L +A D+ +T +P KA L + +Y I + + L S Sbjct: 15 LFKQGLYREAVHCYDQLITAQPQNPVGYSNKAMALIKLGEYTQAIQMCQQGLRYTSTA 72 >5UDI-A nrPDB Length = 479 Score = 31.7 bits (70), Expect = 1.00, Method: Composition-based stats. Identities = 23/125 (18%), Positives = 35/125 (28%), Gaps = 20/125 (16%) Query: 372 SVQALLLKGAALRNMGRVQEAIIHFREAIRL---------APCRLDCYEGLIECYLASNS 422 SV L G+ +EA+ +EA L L + Y Sbjct: 52 SVGIHNLLAYVKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGR 111 Query: 423 IREAMVMANNVYKTLG--ANAQTLTLLATV--CLEDPVTQ-------EKAKTLLDKALTQ 471 + EA + V +N + C E E+AK +K L Sbjct: 112 LAEAQTYLDKVENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEV 171 Query: 472 RPDYI 476 P+ Sbjct: 172 DPENP 176 >4HOU-A nrPDB Length = 273 Score = 31.3 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 23/125 (18%), Positives = 35/125 (28%), Gaps = 20/125 (16%) Query: 372 SVQALLLKGAALRNMGRVQEAIIHFREAIRL---------APCRLDCYEGLIECYLASNS 422 SV L G+ +EA+ +EA L L + Y Sbjct: 45 SVGIHNLLAYVKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGR 104 Query: 423 IREAMVMANNVYKTLG--ANAQTLTLLATV--CLEDPVTQ-------EKAKTLLDKALTQ 471 + EA + V +N + C E E+AK +K L Sbjct: 105 LAEAQTYLDKVENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEV 164 Query: 472 RPDYI 476 P+ Sbjct: 165 DPENP 169 >5GVE-A nrPDB Length = 613 Score = 31.3 bits (69), Expect = 1.3, Method: Composition-based stats. Identities = 23/80 (28%), Positives = 37/80 (46%), Gaps = 4/80 (5%) Query: 131 CLPSEIEVKYKMAECYTMLK----QDKDAIAILDGIPSRQRTPKINMMLANLYKKAGQER 186 C+ +++ E Y +L+ DKD +LD R +I M N+ K + + Sbjct: 226 CVERHDKIQSFKPETYWVLQAKVNTDKDRSLLLDWDRVRVFDREIAQMFLNMTKLEKEAQ 285 Query: 187 PSVTSYKEVLRQCPLALDAI 206 TS KE +Q PLAL+ + Sbjct: 286 VEATSRKEKAKQRPLALNTV 305 >3ZN3-A nrPDB Length = 291 Score = 31.3 bits (69), Expect = 1.4, Method: Composition-based stats. Identities = 33/239 (13%), Positives = 71/239 (29%), Gaps = 26/239 (10%) Query: 277 LADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDV--ENLGCRLFNI 334 LA YF + + + + + ++ +Y LA E + E+ L L Sbjct: 76 LAKSYFDCKEFERAAYTLQNCKSSKSIFLR---LYSKYLAGEKKSEEENETLLNTNLTLS 132 Query: 335 SDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAII 394 S ++ S + + + + L G R + +AI Sbjct: 133 STNREFYYISEVLESLHYQGNK------------DPYLLY---LSGVVYRKRKQDSKAID 177 Query: 395 HFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVCLED 454 + + AP + L + ++ + + + + E Sbjct: 178 FLKSCVLKAPFFWSAWLELSLSIDSLETLTTVVSQLPSTHIMTKI---FYVYASH---EL 231 Query: 455 PVTQEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCVLHR 513 A L +A P+ ++A L + +++ +L N L N L+ Sbjct: 232 HQVNSSAYEKLAEAEIIFPNSRYLKTQRALLTYDSRDFDEAESLFENILTNDPAENLYF 290 >3NF1-A nrPDB Length = 311 Score = 30.9 bits (68), Expect = 1.7, Method: Composition-based stats. Identities = 23/160 (14%), Positives = 48/160 (30%), Gaps = 23/160 (14%) Query: 369 NSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLA--------PCRLDCYEGLIECYLAS 420 + + L + R+ + ++A +A+ + P L Y Sbjct: 65 HPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKR 124 Query: 421 NSIREAMVMANNV----YKTLGAN-AQTLTLLATVCL--EDPVTQEKAKTLLDKALTQ-- 471 +EA + K LG + L + L ++ E+ + +AL Sbjct: 125 GKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQ 184 Query: 472 ------RPDYIKAVVKKAELLSREQKYEDGIALLRNALAN 505 P+ K A ++ K++ L + L Sbjct: 185 TKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTR 224 >5OJ8-A nrPDB Length = 255 Score = 30.5 bits (67), Expect = 1.9, Method: Composition-based stats. Identities = 23/160 (14%), Positives = 48/160 (30%), Gaps = 23/160 (14%) Query: 369 NSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLA--------PCRLDCYEGLIECYLAS 420 + + L + R+ + ++A +A+ + P L Y Sbjct: 88 HPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKR 147 Query: 421 NSIREAMVMANNV----YKTLGAN-AQTLTLLATVCL--EDPVTQEKAKTLLDKALTQ-- 471 +EA + K LG + L + L ++ E+ + +AL Sbjct: 148 GKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQ 207 Query: 472 ------RPDYIKAVVKKAELLSREQKYEDGIALLRNALAN 505 P+ K A ++ K++ L + L Sbjct: 208 TKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTR 247 >2GNO-A nrPDB Length = 305 Score = 30.5 bits (67), Expect = 2.3, Method: Composition-based stats. Identities = 13/100 (13%), Positives = 36/100 (36%), Gaps = 4/100 (4%) Query: 437 LGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGI 496 L + + T + + ++A KAL + P+Y V+ + + Sbjct: 74 LNYSPELYTRKYVIVHDCERMTQQAANAFLKALEEPPEYAVIVLNTRRWHYLLPTIKSRV 133 Query: 497 ALLRNALANQSDCVLHRILGDFLVAV----NEYQEAMDQY 532 + + + ++ +GD + +++ A++ Y Sbjct: 134 FRVVVNVPKEFRDLVKEKIGDLWEELPLLERDFKTALEAY 173 >5C9S-B nrPDB Length = 572 Score = 30.1 bits (66), Expect = 2.6, Method: Composition-based stats. Identities = 31/239 (12%), Positives = 79/239 (33%), Gaps = 11/239 (4%) Query: 251 NSRAISTICSLEKKSLLRDNVDLLGSLADLY-FRAGDNKNSVLKFEQAQMLDPYL--IKG 307 N+RA ++ E+ + N ++ + + + + + E+A + + Sbjct: 297 NTRAPESVADFERLLIGNPNSSVVWMNYMAFQLQLSEIEKARELAERALKTINFREEAEK 356 Query: 308 MDVYGYLLARE---GRLEDVENLGCRLFN-ISDQHAEPWVVSGCHSFYSKRYSRALYLGA 363 ++++ +L E G E +E + R + ++ G + K A A Sbjct: 357 LNIWIAMLNLENTFGTEETLEEVFSRACQYMDSYTIHTKLL-GIYEISEKFDKAAELFKA 415 Query: 364 KAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPC--RLDCYEGLIECYLASN 421 A + V + G L + QEA A++ P ++ + A Sbjct: 416 TAKKFGGEKVSIWVSWGDFLISHNEEQEARTILGNALKALPKRNHIEVVRKFAQLEFAKG 475 Query: 422 SIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVV 480 + + + ++ ++K + L ++ +T++ +A Sbjct: 476 DPERGRSLFEGLVADAPKRIDLWNVYVDQEVKAK-DKKKVEDLFERIITKKITRKQAKF 533 >1KT1-A nrPDB Length = 457 Score = 30.1 bits (66), Expect = 2.6, Method: Composition-based stats. Identities = 24/158 (15%), Positives = 59/158 (37%), Gaps = 19/158 (12%) Query: 268 RDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENL 327 + ++ +YF+ G +V+++ + + +++ L +E + + L Sbjct: 265 LEQAAIVKEKGTVYFKGGKYVQAVIQYGKI-------VSWLEMEYGLSEKESKASESFLL 317 Query: 328 GCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMG 387 L ++ C+ + Y++A+ KA+ L+S + + L +G A M Sbjct: 318 AAFLN-----------LAMCY-LKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMN 365 Query: 388 RVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIRE 425 + A F + + + P + C + E Sbjct: 366 EFESAKGDFEKVLEVNPQNKAARLQIFMCQKKAKEHNE 403 >5NLG-A nrPDB Length = 314 Score = 29.7 bits (65), Expect = 3.5, Method: Composition-based stats. Identities = 31/239 (12%), Positives = 79/239 (33%), Gaps = 11/239 (4%) Query: 251 NSRAISTICSLEKKSLLRDNVDLLGSLADLY-FRAGDNKNSVLKFEQAQMLDPYL--IKG 307 N+RA ++ E+ + N ++ + + + + + E+A + + Sbjct: 47 NTRAPESVADFERLLIGNPNSSVVWMNYMAFQLQLSEIEKARELAERALKTINFREEAEK 106 Query: 308 MDVYGYLLARE---GRLEDVENLGCRLFN-ISDQHAEPWVVSGCHSFYSKRYSRALYLGA 363 ++++ +L E G E +E + R + ++ G + K A A Sbjct: 107 LNIWIAMLNLENTFGTEETLEEVFSRACQYMDSYTIHTKLL-GIYEISEKFDKAAELFKA 165 Query: 364 KAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPC--RLDCYEGLIECYLASN 421 A + V + G L + QEA A++ P ++ + A Sbjct: 166 TAKKFGGEKVSIWVSWGDFLISHNEEQEARTILGNALKALPKRNHIEVVRKFAQLEFAKG 225 Query: 422 SIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVV 480 + + + ++ ++K + L ++ +T++ +A Sbjct: 226 DPERGRSLFEGLVADAPKRIDLWNVYVDQEVKAK-DKKKVEDLFERIITKKITRKQAKF 283 >2N98-A nrPDB Length = 90 Score = 29.7 bits (65), Expect = 3.6, Method: Composition-based stats. Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 2/57 (3%) Query: 224 MNVIQTVPNLDWLSVWIKAYAFVHTGDNSRAISTICSLEKKSLLRDNVDLLGSLADL 280 M+ + T P LD L VW+ H G ++ I+T L L D+V L A+L Sbjct: 3 MSDLSTAPTLDSLRVWLVDCVAGHLGLDAATIATDLPLTSYGL--DSVYALSIAAEL 57 >4IN3-B nrPDB Length = 739 Score = 29.7 bits (65), Expect = 3.7, Method: Composition-based stats. Identities = 36/212 (16%), Positives = 66/212 (31%), Gaps = 14/212 (6%) Query: 398 EAIRLAPCRLDCYEGLIECYLASNSIREA--------MVMANNVYKTLGANAQTLTLLAT 449 EA+ AP + L Y+ N + A M Y T Sbjct: 375 EAVNCAPNEFKTWYLLTRIYIKLNDMSNALLSLNACPMSQVKEKYVLRRIAPITSDENLH 434 Query: 450 VCLEDPVTQEK--AKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQS 507 + L + E+ + +D L Q+ V A L ++ LL + Sbjct: 435 LPLPLDASIEEISSLNPMDVQLEQKSADPNLVNLSASSLKST--FQLAYKLLTEIVQITG 492 Query: 508 DCVLHRILGDFLVAVNEYQEAMDQYSIALSLDPNDQKSLEGMQKMEKEESPTDATQEEDV 567 L + V +EYQ + A + ND + + E+ ED+ Sbjct: 493 WEQLLKYRSKIFVMEDEYQGSTSSIDEA-EVRGNDISKMRSKRLCERWLDNLFMLLYEDL 551 Query: 568 DD-MEGSGEEGDLEGSDSEAAQWADQEQWFGM 598 + E+ + +S+ + + + FG+ Sbjct: 552 KTYTDWQSEQLYFDAQNSKYHKLTVEWELFGL 583 >4MT4-A nrPDB Length = 479 Score = 29.3 bits (64), Expect = 4.8, Method: Composition-based stats. Identities = 20/98 (20%), Positives = 32/98 (32%), Gaps = 12/98 (12%) Query: 350 FYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLD- 408 F + Y A + + SN+VQ A N ++EA +E R+ + Sbjct: 141 FKASEYD----YEAARLSVISNTVQTYFNLVNAYENENALKEAYESAKEIYRINDEKFQV 196 Query: 409 ---CYEGLIECYLASNSI----REAMVMANNVYKTLGA 439 L + S+ EA + N K L Sbjct: 197 GAVGEYELAQARANLESMALQYNEAKLNKENYLKALKI 234 >4GFK-A nrPDB Length = 196 Score = 29.3 bits (64), Expect = 5.3, Method: Composition-based stats. Identities = 22/83 (26%), Positives = 43/83 (51%), Gaps = 13/83 (15%) Query: 18 RLFESVLPPLPAALQSRMN-VIDHVRDMAAAGLHSNVRLLSSLLLTMSNNNPELFSPPQK 76 R+FE ++ + +L SR+N + D +D + +RL+ LLL + NP L Sbjct: 55 RMFEGLIEFIEESLMSRINRIFDEEKDTL-----NRIRLVMQLLLAFAERNPGL------ 103 Query: 77 YQLLVYHADSLFHDKEYRNAVSK 99 ++L HA +F ++ R+ +++ Sbjct: 104 TRILSGHA-LMFENERLRDRINQ 125 >6FUZ-A nrPDB Length = 337 Score = 29.3 bits (64), Expect = 5.5, Method: Composition-based stats. Identities = 29/185 (15%), Positives = 57/185 (30%), Gaps = 31/185 (16%) Query: 352 SKRYSRALYLGAKAIQL--------NSNSVQALLLKGAALRNMGRVQEAIIHFREAI--- 400 RY A+ L +A++ + + L + R+ + ++A +A+ Sbjct: 26 QGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIR 85 Query: 401 -----RLAPCRLDCYEGLIECYLASNSIREAMVMANNV----YKTLGAN-AQTLTLLATV 450 R P L Y +EA + K LG + L + Sbjct: 86 EKTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNL 145 Query: 451 CL--EDPVTQEKAKTLLDKALTQ--------RPDYIKAVVKKAELLSREQKYEDGIALLR 500 L ++ E+ + +AL P+ K A ++ K++ L + Sbjct: 146 ALLCQNQGKYEEVEYYYQRALGIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYK 205 Query: 501 NALAN 505 L Sbjct: 206 EILTR 210 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.316 0.127 0.328 Lambda K H 0.267 0.0392 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 19,497,528 Number of Sequences: 36641 Number of extensions: 690368 Number of successful extensions: 2626 Number of sequences better than 10.0: 66 Number of HSP's better than 10.0 without gapping: 48 Number of HSP's successfully gapped in prelim test: 46 Number of HSP's that attempted gapping in prelim test: 2336 Number of HSP's gapped (non-prelim): 223 length of query: 599 length of database: 10,336,785 effective HSP length: 103 effective length of query: 496 effective length of database: 6,562,762 effective search space: 3255129952 effective search space used: 3255129952 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 62 (28.6 bits)