BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9UJX2 (597 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5G05-C nrPDB 1241 0.0 3ZN3-A nrPDB 127 1e-29 5G04-F nrPDB 123 2e-28 6B85-J nrPDB 66 6e-11 5A01-A nrPDB 45 8e-05 5LVV-A nrPDB 45 1e-04 4M57-A nrPDB 43 4e-04 5KHR-J nrPDB 43 4e-04 5G04-X nrPDB 42 0.001 1W3B-A nrPDB 38 0.011 5JJT-A nrPDB 38 0.015 5ZYQ-A nrPDB 37 0.017 5DSE-A nrPDB 35 0.075 5AEM-A nrPDB 34 0.18 1IHG-A nrPDB 32 0.65 5FOI-A nrPDB 32 0.89 2C2L-A nrPDB 31 1.6 3TJZ-B nrPDB 30 3.4 5A1Y-E nrPDB 30 3.5 4G1T-A nrPDB 28 8.7 >5G05-C nrPDB Length = 597 Score = 1241 bits (3212), Expect = 0.0, Method: Compositional matrix adjust. Identities = 597/597 (100%), Positives = 597/597 (100%) Query: 1 MAASTSMVPVAVTAAVAPVLSINSDFSDLREIKKQLLLIAGLTRERGLLHSSKWSAELAF 60 MAASTSMVPVAVTAAVAPVLSINSDFSDLREIKKQLLLIAGLTRERGLLHSSKWSAELAF Sbjct: 1 MAASTSMVPVAVTAAVAPVLSINSDFSDLREIKKQLLLIAGLTRERGLLHSSKWSAELAF 60 Query: 61 SLPALPLAELQPPPPITEEDAQDMDAYTLAKAYFDVKEYDRAAHFLHGCNSKKAYFLYMY 120 SLPALPLAELQPPPPITEEDAQDMDAYTLAKAYFDVKEYDRAAHFLHGCNSKKAYFLYMY Sbjct: 61 SLPALPLAELQPPPPITEEDAQDMDAYTLAKAYFDVKEYDRAAHFLHGCNSKKAYFLYMY 120 Query: 121 SRYLSGEKKKDDETVDSLGPLEKGQVKNEALRELRVELSKKHQARELDGFGLYLYGVVLR 180 SRYLSGEKKKDDETVDSLGPLEKGQVKNEALRELRVELSKKHQARELDGFGLYLYGVVLR Sbjct: 121 SRYLSGEKKKDDETVDSLGPLEKGQVKNEALRELRVELSKKHQARELDGFGLYLYGVVLR 180 Query: 181 KLDLVKEAIDVFVEATHVLPLHWGAWLELCNLITDKEMLKFLSLPDTWMKEFFLAHIYTE 240 KLDLVKEAIDVFVEATHVLPLHWGAWLELCNLITDKEMLKFLSLPDTWMKEFFLAHIYTE Sbjct: 181 KLDLVKEAIDVFVEATHVLPLHWGAWLELCNLITDKEMLKFLSLPDTWMKEFFLAHIYTE 240 Query: 241 LQLIEEALQKYQNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYRIENM 300 LQLIEEALQKYQNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYRIENM Sbjct: 241 LQLIEEALQKYQNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYRIENM 300 Query: 301 DTFSNLLYVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKL 360 DTFSNLLYVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKL Sbjct: 301 DTFSNLLYVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKL 360 Query: 361 NPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLY 420 NPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLY Sbjct: 361 NPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLY 420 Query: 421 YYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQL 480 YYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQL Sbjct: 421 YYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQL 480 Query: 481 TESEQAAQCYIKYIQDIYSCGEIVEHLEESTAFRYLAQYYFKCKLWDEASTCAQKCCAFN 540 TESEQAAQCYIKYIQDIYSCGEIVEHLEESTAFRYLAQYYFKCKLWDEASTCAQKCCAFN Sbjct: 481 TESEQAAQCYIKYIQDIYSCGEIVEHLEESTAFRYLAQYYFKCKLWDEASTCAQKCCAFN 540 Query: 541 DTREEGKALLRQILQLRNQGETPTTEVPAPFFLPASLSANNTPTRRVSPLNLSSVTP 597 DTREEGKALLRQILQLRNQGETPTTEVPAPFFLPASLSANNTPTRRVSPLNLSSVTP Sbjct: 541 DTREEGKALLRQILQLRNQGETPTTEVPAPFFLPASLSANNTPTRRVSPLNLSSVTP 597 >3ZN3-A nrPDB Length = 291 Score = 127 bits (319), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 90/282 (31%), Positives = 132/282 (46%), Gaps = 16/282 (5%) Query: 29 LREIKKQLLLIAGLTRERGLLHSSKWSAELA----------FSLPALPLAELQPPPPITE 78 LREI+ LL ERGL+++ +W+AE+ + P E P + Sbjct: 3 LREIRNCLLKCISECSERGLVYAVRWAAEMLNGMNPIEMEHIPFSSTPTGEFDLDPDMAN 62 Query: 79 E---DAQDMDAYTLAKAYFDVKEYDRAAHFLHGCNSKKAYFLYMYSRYLSGEKKKDDETV 135 E + ++ + Y LAK+YFD KE++RAA+ L C S K+ FL +YS+YL+GEKK ++E Sbjct: 63 EKLLEVEEKNIYLLAKSYFDCKEFERAAYTLQNCKSSKSIFLRLYSKYLAGEKKSEEENE 122 Query: 136 DSLGPLEKGQVKNEALRELRVELSKKHQARELDGFGLYLYGVVLRKLDLVKEAIDVFVEA 195 L N + L H D + LYL GVV RK +AID Sbjct: 123 TLLNTNLTLSSTNREFYYISEVLESLHYQGNKDPYLLYLSGVVYRKRKQDSKAIDFLKSC 182 Query: 196 THVLPLHWGAWLELCNLITDKEMLKFL--SLPDT-WMKEFFLAHIYTELQLIEEALQKYQ 252 P W AWLEL I E L + LP T M + F + EL + + + Sbjct: 183 VLKAPFFWSAWLELSLSIDSLETLTTVVSQLPSTHIMTKIFYVYASHELHQVNSSAYEKL 242 Query: 253 NLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDP 294 ++ F S Y+ +Q A+ ++ RD D+A S+F + DP Sbjct: 243 AEAEIIFPNSRYLKTQRALLTYDSRDFDEAESLFENILTNDP 284 >5G04-F nrPDB Length = 824 Score = 123 bits (308), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 61/179 (34%), Positives = 105/179 (58%) Query: 262 SSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKSELSYLAH 321 + +++ QI AY + + +A IF+E+R+ + YR+E M+ +S L+ LS L+ Sbjct: 498 TGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSK 557 Query: 322 NLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNT 381 +L ++DK E C GN +SL+ +H+ A +FQRA++++P Y A+TL+GHE++ + Sbjct: 558 DLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEEL 617 Query: 382 SAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALG 440 A+ +R+AI VN R Y AWYGLG Y + ++++A + P S +L +G Sbjct: 618 DKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIG 676 Score = 34.3 bits (77), Expect = 0.16, Method: Compositional matrix adjust. Identities = 50/216 (23%), Positives = 81/216 (37%), Gaps = 31/216 (14%) Query: 152 RELRVELSKKHQARELDGFGLYLYGVVLRKLDLVKE---AIDVFVEATHVLPLHWGAWLE 208 RE + + +A ++D Y Y ++ + L +E A+ F A V P H+ AW Sbjct: 581 REHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAW-- 638 Query: 209 LCNLITDKEMLKFLSLPDTWMKEFFLAHIYTELQLIEEALQKYQNLIDVGFSKSSYIVSQ 268 + L IY + + A +Q +D+ +SS ++ Sbjct: 639 -----------------------YGLGMIYYKQEKFSLAEMHFQKALDIN-PQSSVLLCH 674 Query: 269 IAVAYHNIRDIDKALSIFNELRKQDPYR-IENMDTFSNLLYVRSMKSELSYLAHNLCEID 327 I V H ++ +KAL N+ DP + S L KS L L L +I Sbjct: 675 IGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQEL-EELKQIV 733 Query: 328 KYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPR 363 +IG Y Q A + F A+ L+P+ Sbjct: 734 PKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPK 769 Score = 30.0 bits (66), Expect = 3.3, Method: Compositional matrix adjust. Identities = 24/128 (18%), Positives = 50/128 (39%) Query: 335 CVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEV 394 C IG Y S++ +A F ++ + + ++ A + ++ Sbjct: 503 CQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTDM 562 Query: 395 NKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKK 454 +K AW G + + + + +++RA Q+ PN + LG + +L +A Sbjct: 563 DKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALA 622 Query: 455 CYWRAYAV 462 C+ A V Sbjct: 623 CFRNAIRV 630 >6B85-J nrPDB Length = 223 Score = 65.9 bits (159), Expect = 6e-11, Method: Compositional matrix adjust. Identities = 38/110 (34%), Positives = 59/110 (53%) Query: 350 AALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTY 409 AA +++A++L+P AW L+G ++K A +AY+ AIE+ D AW LG+ Sbjct: 100 AAEAYKKAIELDPNDALAWLLLGSVLEKLKRLDEAAEAYKKAIELKPNDASAWKELGKVL 159 Query: 410 EILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRA 459 E L Y++A +L P D+ LG+ EKL +L EA + Y +A Sbjct: 160 EKLGRLDEAAEAYKKAIELDPEDAEAWKELGKVLEKLGRLDEAAEAYKKA 209 Score = 65.1 bits (157), Expect = 8e-11, Method: Compositional matrix adjust. Identities = 40/112 (35%), Positives = 62/112 (55%) Query: 384 AIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECY 443 A +AY+ AIE++ D AW LG E LK Y++A +L+PND+ LG+ Sbjct: 100 AAEAYKKAIELDPNDALAWLLLGSVLEKLKRLDEAAEAYKKAIELKPNDASAWKELGKVL 159 Query: 444 EKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYIKYIQ 495 EKL +L EA + Y +A + + A +L K+ E+L ++AA+ Y K I+ Sbjct: 160 EKLGRLDEAAEAYKKAIELDPEDAEAWKELGKVLEKLGRLDEAAEAYKKAIE 211 Score = 53.5 bits (127), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 30/109 (27%), Positives = 53/109 (48%) Query: 324 CEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSA 383 E+D ++G+ + ++AA +++A++L P AW +G ++ Sbjct: 108 IELDPNDALAWLLLGSVLEKLKRLDEAAEAYKKAIELKPNDASAWKELGKVLEKLGRLDE 167 Query: 384 AIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPND 432 A +AY+ AIE++ D AW LG+ E L Y++A +L PND Sbjct: 168 AAEAYKKAIELDPEDAEAWKELGKVLEKLGRLDEAAEAYKKAIELDPND 216 >5A01-A nrPDB Length = 710 Score = 45.4 bits (106), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 34/133 (25%), Positives = 63/133 (47%), Gaps = 13/133 (9%) Query: 348 EKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQ 407 ++A ++++ A+++ P + A++ MG+ E+++ S A+Q Y AI++N A L Sbjct: 58 KEALMHYKEAIRIQPTFADAYSNMGNTLKELQDVSGALQCYTRAIQINPAFADAHSNLAS 117 Query: 408 TYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEK 467 ++ + YR A +L+P+ L C Q+V C W Y D+ Sbjct: 118 IHKDSGNIPEAIQSYRTALKLKPDFPDAYCNLAHCL----QIV----CDWTDY---DIRM 166 Query: 468 MALVKLAKLHEQL 480 LV + + EQL Sbjct: 167 KKLVSI--VTEQL 177 Score = 31.2 bits (69), Expect = 1.3, Method: Compositional matrix adjust. Identities = 25/112 (22%), Positives = 47/112 (41%) Query: 348 EKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQ 407 E+A + +AL++ P + A + + + A+ Y+ AI + A+ +G Sbjct: 24 EEATRLYLKALEVFPDFAAAHSNLASVLQQQGKLKEALMHYKEAIRIQPTFADAYSNMGN 83 Query: 408 TYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRA 459 T + L+ L Y RA Q+ P + L ++ + EA + Y A Sbjct: 84 TLKELQDVSGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIQSYRTA 135 Score = 31.2 bits (69), Expect = 1.4, Method: Compositional matrix adjust. Identities = 18/72 (25%), Positives = 33/72 (45%) Query: 419 LYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHE 478 L +Y+ A +++P + +G ++L + A +CY RA + A LA +H+ Sbjct: 61 LMHYKEAIRIQPTFADAYSNMGNTLKELQDVSGALQCYTRAIQINPAFADAHSNLASIHK 120 Query: 479 QLTESEQAAQCY 490 +A Q Y Sbjct: 121 DSGNIPEAIQSY 132 >5LVV-A nrPDB Length = 749 Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 28/113 (24%), Positives = 54/113 (47%), Gaps = 8/113 (7%) Query: 348 EKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQ 407 ++A ++++ A++++P + A++ MG+ EM++ A+Q Y AI++N A L Sbjct: 81 QEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLAS 140 Query: 408 TYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAY 460 ++ + YR A +L+P+ L C Q+V C W Y Sbjct: 141 IHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCL----QIV----CDWTDY 185 Score = 32.7 bits (73), Expect = 0.40, Method: Compositional matrix adjust. Identities = 26/114 (22%), Positives = 45/114 (39%) Query: 377 EMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRML 436 E N A++ YR A+EV A L + L +Y+ A ++ P + Sbjct: 42 EQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAY 101 Query: 437 VALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCY 490 +G +++ + A +CY RA + A LA +H+ +A Y Sbjct: 102 SNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASY 155 Score = 31.2 bits (69), Expect = 1.3, Method: Compositional matrix adjust. Identities = 24/112 (21%), Positives = 48/112 (42%) Query: 348 EKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQ 407 E+A +++AL++ P + A + + + A+ Y+ AI ++ A+ +G Sbjct: 47 EEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGN 106 Query: 408 TYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRA 459 T + ++ L Y RA Q+ P + L ++ + EA Y A Sbjct: 107 TLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTA 158 >4M57-A nrPDB Length = 726 Score = 43.1 bits (100), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 22/95 (23%), Positives = 49/95 (51%), Gaps = 2/95 (2%) Query: 234 LAHIYTELQLIEEALQKYQNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQD 293 LA Y EEA + + G +++ + + AY N+ +D+AL++F++++K Sbjct: 261 LAGTYARAGFFEEAARCLDTMASKGLLPNAFTYNTVMTAYGNVGKVDEALALFDQMKKTG 320 Query: 294 PYRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDK 328 + N++T++ +L + KS + + L E+ + Sbjct: 321 --FVPNVNTYNLVLGMLGKKSRFTVMLEMLGEMSR 353 >5KHR-J nrPDB Length = 620 Score = 42.7 bits (99), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 91/405 (22%), Positives = 161/405 (39%), Gaps = 67/405 (16%) Query: 76 ITEEDAQDMDAYTLAKAYFDVKEYDRAAHFLHGCNSKKAYFLYMYSRYLSG-------EK 128 ++ E+ QD+ Y LA+ + +Y RAAH L S+K LY RYL+ E Sbjct: 32 LSREEPQDI--YWLAQCLYLTAQYHRAAHAL---RSRKLDKLYEACRYLAARCHYAAKEH 86 Query: 129 KKDDETVDSLGPLEK----GQVKNEA----------LRELRVELS------KKHQARELD 168 ++ + +D P+ K +K+E+ + + ++ S K + A + Sbjct: 87 QQALDVLDMEEPINKRLFEKYLKDESGFKDPSSDWEMSQSSIKSSICLLRGKIYDALDNR 146 Query: 169 GFGLYLYGVVLRKLDL-VKEAIDVFV-----------EATHVLPLHWGAWLELCNLITDK 216 Y Y L KLD+ EA D+ E LPL +LCN ++ Sbjct: 147 TLATYSYKEAL-KLDVYCFEAFDLLTSHHMLTAQEEKELLESLPLS-----KLCN--EEQ 198 Query: 217 EMLKFLSLPDTWMKEFFLAHIYTELQLIEEALQKYQNLIDVGFSKSSYIVSQIAVAYHNI 276 E+L+FL + + +I E++ Q +DV +VS Y+N Sbjct: 199 ELLRFL------FENKLKKYNKPSETVIPESVDGLQENLDV-------VVSLAERHYYNC 245 Query: 277 RDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDKYRVETCCV 336 D + + + ++DP+ + L + +EL YL+H L ++ + Sbjct: 246 -DFKMCYKLTSVVMEKDPFHASCLPVHIGTLVELNKANELFYLSHKLVDLYPSNPVSWFA 304 Query: 337 IGNYYSLRS-QHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVN 395 +G YY + ++E A Y +A L Y AW GH + A+ AY A ++ Sbjct: 305 VGCYYLMVGHKNEHARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLM 364 Query: 396 KRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALG 440 K + +G Y + ++ +A + P D ++ +G Sbjct: 365 KGCHLPMLYIGLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEVG 409 >5G04-X nrPDB Length = 599 Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust. Identities = 51/202 (25%), Positives = 81/202 (40%), Gaps = 12/202 (5%) Query: 211 NLITDKEMLKFLSLPDTWMKEFFLAHIYTELQLIEE--ALQKYQNLIDVGFSKSSYIVSQ 268 N+I L +LS+ W+K + H + I +L+K L D + ++ Sbjct: 225 NVIQTVPNLDWLSV---WIKAYAFVHTGDNSRAISTICSLEKKSLLRD-----NVDLLGS 276 Query: 269 IAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDK 328 +A Y D ++ F + + DPY I+ MD + LL ++ L L I Sbjct: 277 LADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISD 336 Query: 329 YRVETCCVIGNYYSLRSQHEKAALYF-QRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQA 387 E V G +S S+ ALY +A++LN + A L G M AI Sbjct: 337 QHAEPWVVSG-CHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIH 395 Query: 388 YRHAIEVNKRDYRAWYGLGQTY 409 +R AI + + GL + Y Sbjct: 396 FREAIRLAPCRLDCYEGLIECY 417 >1W3B-A nrPDB Length = 388 Score = 38.1 bits (87), Expect = 0.011, Method: Compositional matrix adjust. Identities = 30/112 (26%), Positives = 49/112 (43%) Query: 348 EKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQ 407 +++A + A+K NP A++ +G+ Y E AI+ YRHA+ + + L Sbjct: 50 DRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAA 109 Query: 408 TYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRA 459 + Y A Q P+ + LG + L +L EAK CY +A Sbjct: 110 ALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKA 161 Score = 37.7 bits (86), Expect = 0.014, Method: Compositional matrix adjust. Identities = 40/205 (19%), Positives = 77/205 (37%), Gaps = 37/205 (18%) Query: 328 KYRVETCCV---IGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAA 384 +Y + CV +GN + E+A + +A++ P + AW+ +G + A Sbjct: 129 QYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLA 188 Query: 385 IQAYRHAIEVNKRDYRAWYGLGQ-----------------------TYEILKMPFYCLYY 421 I + A+ ++ A+ LG + ++ C+YY Sbjct: 189 IHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYY 248 Query: 422 -----------YRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMAL 470 YRRA +L+P+ L ++ + EA+ CY A + +L Sbjct: 249 EQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSL 308 Query: 471 VKLAKLHEQLTESEQAAQCYIKYIQ 495 LA + + E+A + Y K ++ Sbjct: 309 NNLANIKREQGNIEEAVRLYRKALE 333 Score = 37.4 bits (85), Expect = 0.020, Method: Compositional matrix adjust. Identities = 24/95 (25%), Positives = 44/95 (46%) Query: 337 IGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNK 396 +GN Y R Q ++A +++ AL+L P ++ + + + + A+QAY A++ N Sbjct: 73 LGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNP 132 Query: 397 RDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPN 431 Y LG + L Y +A + +PN Sbjct: 133 DLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPN 167 Score = 33.1 bits (74), Expect = 0.31, Method: Compositional matrix adjust. Identities = 42/216 (19%), Positives = 94/216 (43%), Gaps = 14/216 (6%) Query: 176 GVVLRKLDLVKEAIDVFVEATHVLPLHWGAWLELCNLITDKEM--------LKFLSL-PD 226 G V + AI F +A + P A++ L N++ + + L+ LSL P+ Sbjct: 176 GCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPN 235 Query: 227 TWMKEFFLAHIYTELQLIEEALQKYQNLIDVG--FSKSSYIVSQIAVAYHNIRDIDKALS 284 + LA +Y E LI+ A+ Y+ I++ F + +A A + +A Sbjct: 236 HAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDA---YCNLANALKEKGSVAEAED 292 Query: 285 IFNELRKQDPYRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLR 344 +N + P ++++ +N+ + E L E+ + + + Sbjct: 293 CYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQ 352 Query: 345 SQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKN 380 + ++A ++++ A++++P + A++ MG+ EM++ Sbjct: 353 GKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQD 388 >5JJT-A nrPDB Length = 479 Score = 37.7 bits (86), Expect = 0.015, Method: Compositional matrix adjust. Identities = 24/96 (25%), Positives = 44/96 (45%) Query: 354 FQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILK 413 + +A++LN W + +++ +AIQ AIEV+ R + +Y G Y + Sbjct: 32 YTKAIELNSNNAVYWANRAFAHTKLEEYGSAIQDASKAIEVDSRYSKGYYRRGAAYLAMG 91 Query: 414 MPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQL 449 L +++ +L PND L EC + + +L Sbjct: 92 KFKDALKDFQQVKRLSPNDPDATRKLKECEKAVMKL 127 >5ZYQ-A nrPDB Length = 320 Score = 37.4 bits (85), Expect = 0.017, Method: Compositional matrix adjust. Identities = 28/102 (27%), Positives = 46/102 (45%), Gaps = 17/102 (16%) Query: 392 IEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPN-DSRMLVALGECYEKLNQLV 450 I NK+DYR L YY++A + P + + + +G C+ KLN+L Sbjct: 172 ISFNKKDYRG----------------ALAYYKKALRTNPGCPAEVRLGMGHCFVKLNKLE 215 Query: 451 EAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYIK 492 +A+ + RA + ALV LA L E++ + Y + Sbjct: 216 KARLAFSRALELNSKCVGALVGLAVLELNNKEADGSENLYFQ 257 Score = 31.2 bits (69), Expect = 1.2, Method: Compositional matrix adjust. Identities = 18/64 (28%), Positives = 32/64 (50%), Gaps = 1/64 (1%) Query: 344 RSQHEKAALYFQRALKLNPRYLGAWTL-MGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAW 402 + + A Y+++AL+ NP L MGH ++++ A A+ A+E+N + A Sbjct: 176 KKDYRGALAYYKKALRTNPGCPAEVRLGMGHCFVKLNKLEKARLAFSRALELNSKCVGAL 235 Query: 403 YGLG 406 GL Sbjct: 236 VGLA 239 Score = 31.2 bits (69), Expect = 1.4, Method: Compositional matrix adjust. Identities = 18/47 (38%), Positives = 29/47 (61%), Gaps = 2/47 (4%) Query: 337 IGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSA 383 +G+ + ++ EKA L F RAL+LN + +GA L+G +E+ N A Sbjct: 204 MGHCFVKLNKLEKARLAFSRALELNSKCVGA--LVGLAVLELNNKEA 248 >5DSE-A nrPDB Length = 837 Score = 35.4 bits (80), Expect = 0.075, Method: Compositional matrix adjust. Identities = 17/73 (23%), Positives = 36/73 (49%) Query: 338 GNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKR 397 G LR ++A +++ AL ++P ++ + + ++ S A + R A++VN Sbjct: 731 GQIAELRGSMDEARRWYEEALAISPTHVKSMQRLALILHQLGRYSLAEKILRDAVQVNST 790 Query: 398 DYRAWYGLGQTYE 410 + W GLG+ + Sbjct: 791 AHEVWNGLGEVLQ 803 >5AEM-A nrPDB Length = 447 Score = 34.3 bits (77), Expect = 0.18, Method: Compositional matrix adjust. Identities = 32/155 (20%), Positives = 57/155 (36%) Query: 338 GNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKR 397 N +R+ + A F +K + R A+ +G Y + ++ A +N Sbjct: 16 ANEAFVRNDLQVAERLFNEVIKKDARNFAAYETLGDIYQLQGRLNDCCNSWFLAAHLNAS 75 Query: 398 DYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYW 457 D+ W + L +Y + R L P + + Y+K QL A + Sbjct: 76 DWEFWKIVAILSADLDHVRQAIYCFSRVISLNPMEWESIYRRSMLYKKTGQLARALDGFQ 135 Query: 458 RAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYIK 492 R Y + L +LA L+ E + + Y+K Sbjct: 136 RLYMYNPYDANILRELAILYVDYDRIEDSIELYMK 170 Score = 28.5 bits (62), Expect = 7.8, Method: Compositional matrix adjust. Identities = 28/152 (18%), Positives = 63/152 (41%), Gaps = 2/152 (1%) Query: 336 VIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVN 395 +G+ Y L+ + + A LN W ++ ++ + AI + I +N Sbjct: 48 TLGDIYQLQGRLNDCCNSWFLAAHLNASDWEFWKIVAILSADLDHVRQAIYCFSRVISLN 107 Query: 396 KRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKC 455 ++ + Y Y+ L ++R + P D+ +L L Y +++ ++ + Sbjct: 108 PMEWESIYRRSMLYKKTGQLARALDGFQRLYMYNPYDANILRELAILYVDYDRIEDSIEL 167 Query: 456 YWRAYAVGDVEKMALVKLAKLHEQLTESEQAA 487 Y + + +VE+ + LA L L S++ + Sbjct: 168 YMKVFN-ANVERREAI-LAALENALDSSDEES 197 >1IHG-A nrPDB Length = 370 Score = 32.3 bits (72), Expect = 0.65, Method: Compositional matrix adjust. Identities = 26/117 (22%), Positives = 52/117 (44%), Gaps = 1/117 (0%) Query: 346 QHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGL 405 + +AA KL P L +G ++M + A+ + A+E++ + +A Y Sbjct: 254 EGSRAAAEDADGAKLQPVALSCVLNIGACKLKMSDWQGAVDSCLEALEIDPSNTKALYRR 313 Query: 406 GQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLN-QLVEAKKCYWRAYA 461 Q ++ LK L ++A ++ P D + L + +K+ Q + K Y + +A Sbjct: 314 AQGWQGLKEYDQALADLKKAQEIAPEDKAIQAELLKVKQKIKAQKDKEKAAYAKMFA 370 >5FOI-A nrPDB Length = 408 Score = 32.0 bits (71), Expect = 0.89, Method: Compositional matrix adjust. Identities = 21/75 (28%), Positives = 36/75 (48%), Gaps = 2/75 (2%) Query: 411 ILKMPFYCLYYYRRAHQL--RPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKM 468 +L +P+ +++ +L RPND R + AL E E L+ LV K + +G Sbjct: 166 LLGVPYEDREFFQERSELASRPNDDRSMPALIELVEYLDGLVRTKTAHPDTGLLGTAVTE 225 Query: 469 ALVKLAKLHEQLTES 483 L+K H++L + Sbjct: 226 RLLKGEITHQELVNN 240 >2C2L-A nrPDB Length = 281 Score = 30.8 bits (68), Expect = 1.6, Method: Compositional matrix adjust. Identities = 19/70 (27%), Positives = 36/70 (51%) Query: 338 GNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKR 397 GN + ++ +AA + RA+ NP +T Y++M+ A+ R A+E++ + Sbjct: 11 GNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQPEQALADCRRALELDGQ 70 Query: 398 DYRAWYGLGQ 407 +A + LGQ Sbjct: 71 SVKAHFFLGQ 80 >3TJZ-B nrPDB Length = 355 Score = 29.6 bits (65), Expect = 3.4, Method: Compositional matrix adjust. Identities = 24/63 (38%), Positives = 30/63 (47%), Gaps = 4/63 (6%) Query: 528 EASTCAQKCCAFNDTREEGKA---LLRQILQLRNQGE-TPTTEVPAPFFLPASLSANNTP 583 E S Q+ FN+T + +L +IL L NQGE TTE FF L +N P Sbjct: 23 EKSAVLQEARVFNETPINPRKCAHILTKILYLINQGEHLGTTEATEAFFAMTKLFQSNDP 82 Query: 584 TRR 586 T R Sbjct: 83 TLR 85 >5A1Y-E nrPDB Length = 874 Score = 29.6 bits (65), Expect = 3.5, Method: Compositional matrix adjust. Identities = 24/63 (38%), Positives = 30/63 (47%), Gaps = 4/63 (6%) Query: 528 EASTCAQKCCAFNDTREEGKA---LLRQILQLRNQGE-TPTTEVPAPFFLPASLSANNTP 583 E S Q+ FN+T + +L +IL L NQGE TTE FF L +N P Sbjct: 23 EKSAVLQEARVFNETPINPRKCAHILTKILYLINQGEHLGTTEATEAFFAMTKLFQSNDP 82 Query: 584 TRR 586 T R Sbjct: 83 TLR 85 >4G1T-A nrPDB Length = 472 Score = 28.5 bits (62), Expect = 8.7, Method: Compositional matrix adjust. Identities = 41/183 (22%), Positives = 78/183 (42%), Gaps = 39/183 (21%) Query: 242 QLIEEALQKYQNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDP------- 294 +L+EEAL+K + DV S + + Y + DKA+ + + + P Sbjct: 234 KLVEEALEKAPGVTDVLRSAAKF--------YRRKDEPDKAIELLKKALEYIPNNAYLHC 285 Query: 295 -----YR---IENMDTFSNLLYVRSMKSELSYLAHNLCEIDK--------YRVETCCVIG 338 YR + M+ N +Y + EL + H + + K +RV C ++ Sbjct: 286 QIGCCYRAKVFQVMNLRENGMYGKRKLLEL--IGHAVAHLKKADEANDNLFRV--CSILA 341 Query: 339 NYYSLRSQHEKAALYFQRAL--KLNP--RYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEV 394 + ++L Q+E+A YFQ+ +L P + L + +MK AI + +++ Sbjct: 342 SLHALADQYEEAEYYFQKEFSKELTPVAKQLLHLRYGNFQLYQMKCEDKAIHHFIEGVKI 401 Query: 395 NKR 397 N++ Sbjct: 402 NQK 404 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5G05-C nrPDB 905 0.0 5KHR-J nrPDB 340 1e-93 3ZN3-A nrPDB 324 6e-89 5G04-F nrPDB 244 7e-65 5G04-X nrPDB 210 1e-54 5A01-A nrPDB 163 2e-40 5LVV-A nrPDB 161 7e-40 6B85-J nrPDB 135 5e-32 4M57-A nrPDB 102 6e-22 Sequences not found previously or not previously below threshold: 1W3B-A nrPDB 145 4e-35 5NNP-A nrPDB 68 2e-11 5JJT-A nrPDB 62 8e-10 5DSE-A nrPDB 59 5e-09 6FO1-G nrPDB 59 5e-09 5AEM-A nrPDB 59 7e-09 2GW1-A nrPDB 57 2e-08 5FZQ-A nrPDB 57 3e-08 6C95-A nrPDB 57 3e-08 4JA9-A nrPDB 56 6e-08 4G1T-A nrPDB 52 7e-07 6AHD-N nrPDB 51 1e-06 5XJC-J nrPDB 51 1e-06 3JB9-R nrPDB 50 3e-06 5WQL-B nrPDB 50 4e-06 1A17-A nrPDB 49 5e-06 2C2L-A nrPDB 49 5e-06 5ZYQ-A nrPDB 48 9e-06 6AF0-A nrPDB 48 1e-05 4ZLH-A nrPDB 47 2e-05 4I9E-A nrPDB 47 2e-05 5UDI-A nrPDB 47 2e-05 5JZ6-A nrPDB 46 3e-05 4HOQ-A nrPDB 44 1e-04 1IHG-A nrPDB 44 1e-04 3JCM-G nrPDB 44 2e-04 2Y4T-A nrPDB 44 2e-04 4UZY-A nrPDB 42 7e-04 5OMP-A nrPDB 41 0.002 4JHR-A nrPDB 39 0.005 1KT1-A nrPDB 39 0.008 1QZ2-A nrPDB 39 0.008 5OJF-A nrPDB 39 0.009 3ZFW-A nrPDB 37 0.016 4ABN-A nrPDB 37 0.018 5OJ8-A nrPDB 37 0.021 5IC8-A nrPDB 37 0.022 3NF1-A nrPDB 37 0.026 5OQL-E nrPDB 37 0.029 5O09-1C nrPDB 36 0.050 4HOU-A nrPDB 36 0.051 5ZYP-A nrPDB 35 0.096 3GYZ-A nrPDB 35 0.12 5GMK-d nrPDB 34 0.14 4GYO-A nrPDB 34 0.14 6FUZ-A nrPDB 34 0.14 5LJ5-S nrPDB 34 0.22 6ICZ-I nrPDB 34 0.27 1ZU2-A nrPDB 33 0.45 3TJZ-B nrPDB 32 0.54 5JHE-A nrPDB 32 0.56 5A1Y-E nrPDB 32 0.59 5WLC-LP nrPDB 32 0.67 6FRK-r nrPDB 32 0.79 2IF4-A nrPDB 31 1.5 3LY9-A nrPDB 31 1.9 5WRW-A nrPDB 30 3.0 6G70-A nrPDB 30 3.2 5UWZ-A nrPDB 30 3.5 6N3Q-F nrPDB 29 5.2 6HTS-R nrPDB 29 8.9 >5G05-C nrPDB Length = 597 Score = 905 bits (2339), Expect = 0.0, Method: Composition-based stats. Identities = 597/597 (100%), Positives = 597/597 (100%) Query: 1 MAASTSMVPVAVTAAVAPVLSINSDFSDLREIKKQLLLIAGLTRERGLLHSSKWSAELAF 60 MAASTSMVPVAVTAAVAPVLSINSDFSDLREIKKQLLLIAGLTRERGLLHSSKWSAELAF Sbjct: 1 MAASTSMVPVAVTAAVAPVLSINSDFSDLREIKKQLLLIAGLTRERGLLHSSKWSAELAF 60 Query: 61 SLPALPLAELQPPPPITEEDAQDMDAYTLAKAYFDVKEYDRAAHFLHGCNSKKAYFLYMY 120 SLPALPLAELQPPPPITEEDAQDMDAYTLAKAYFDVKEYDRAAHFLHGCNSKKAYFLYMY Sbjct: 61 SLPALPLAELQPPPPITEEDAQDMDAYTLAKAYFDVKEYDRAAHFLHGCNSKKAYFLYMY 120 Query: 121 SRYLSGEKKKDDETVDSLGPLEKGQVKNEALRELRVELSKKHQARELDGFGLYLYGVVLR 180 SRYLSGEKKKDDETVDSLGPLEKGQVKNEALRELRVELSKKHQARELDGFGLYLYGVVLR Sbjct: 121 SRYLSGEKKKDDETVDSLGPLEKGQVKNEALRELRVELSKKHQARELDGFGLYLYGVVLR 180 Query: 181 KLDLVKEAIDVFVEATHVLPLHWGAWLELCNLITDKEMLKFLSLPDTWMKEFFLAHIYTE 240 KLDLVKEAIDVFVEATHVLPLHWGAWLELCNLITDKEMLKFLSLPDTWMKEFFLAHIYTE Sbjct: 181 KLDLVKEAIDVFVEATHVLPLHWGAWLELCNLITDKEMLKFLSLPDTWMKEFFLAHIYTE 240 Query: 241 LQLIEEALQKYQNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYRIENM 300 LQLIEEALQKYQNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYRIENM Sbjct: 241 LQLIEEALQKYQNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYRIENM 300 Query: 301 DTFSNLLYVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKL 360 DTFSNLLYVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKL Sbjct: 301 DTFSNLLYVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKL 360 Query: 361 NPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLY 420 NPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLY Sbjct: 361 NPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLY 420 Query: 421 YYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQL 480 YYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQL Sbjct: 421 YYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQL 480 Query: 481 TESEQAAQCYIKYIQDIYSCGEIVEHLEESTAFRYLAQYYFKCKLWDEASTCAQKCCAFN 540 TESEQAAQCYIKYIQDIYSCGEIVEHLEESTAFRYLAQYYFKCKLWDEASTCAQKCCAFN Sbjct: 481 TESEQAAQCYIKYIQDIYSCGEIVEHLEESTAFRYLAQYYFKCKLWDEASTCAQKCCAFN 540 Query: 541 DTREEGKALLRQILQLRNQGETPTTEVPAPFFLPASLSANNTPTRRVSPLNLSSVTP 597 DTREEGKALLRQILQLRNQGETPTTEVPAPFFLPASLSANNTPTRRVSPLNLSSVTP Sbjct: 541 DTREEGKALLRQILQLRNQGETPTTEVPAPFFLPASLSANNTPTRRVSPLNLSSVTP 597 >5KHR-J nrPDB Length = 620 Score = 340 bits (871), Expect = 1e-93, Method: Composition-based stats. Identities = 95/467 (20%), Positives = 176/467 (37%), Gaps = 74/467 (15%) Query: 76 ITEEDAQDMDAYTLAKAYFDVKEYDRAAHFLHGCNSKKAYFLYMYSRYLSG-------EK 128 ++ E+ QD+ Y LA+ + +Y RAAH L S+K LY RYL+ E Sbjct: 32 LSREEPQDI--YWLAQCLYLTAQYHRAAHAL---RSRKLDKLYEACRYLAARCHYAAKEH 86 Query: 129 KKDDETVDSLGPLEK----GQVKNE----------ALRELRVELS------KKHQARELD 168 ++ + +D P+ K +K+E + + ++ S K + A + Sbjct: 87 QQALDVLDMEEPINKRLFEKYLKDESGFKDPSSDWEMSQSSIKSSICLLRGKIYDALDNR 146 Query: 169 GFGLYLYGVVLRKLDLVKEAIDVFV-----------EATHVLPLHWGAWLELCNLITDKE 217 Y Y L+ EA D+ E LPL +LCN ++E Sbjct: 147 TLATYSYKEALKLDVYCFEAFDLLTSHHMLTAQEEKELLESLPLS-----KLCN--EEQE 199 Query: 218 MLKFLSLPDTWMKEFFLAHIYTELQLIEEALQKYQNLIDVGFSKSSYIVSQIAVAYHNIR 277 +L+FL + + +I E++ Q +DV +VS Y+N Sbjct: 200 LLRFL------FENKLKKYNKPSETVIPESVDGLQENLDV-------VVSLAERHYYNC- 245 Query: 278 DIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDKYRVETCCVI 337 D + + + ++DP+ + L + +EL YL+H L ++ + + Sbjct: 246 DFKMCYKLTSVVMEKDPFHASCLPVHIGTLVELNKANELFYLSHKLVDLYPSNPVSWFAV 305 Query: 338 GNYYSLRS-QHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNK 396 G YY + ++E A Y +A L Y AW GH + A+ AY A ++ K Sbjct: 306 GCYYLMVGHKNEHARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMK 365 Query: 397 RDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCY 456 + +G Y + ++ +A + P D ++ +G + + A+K + Sbjct: 366 GCHLPMLYIGLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQNGEWKTAEKWF 425 Query: 457 WRAYAV-----GDVEKMALV----KLAKLHEQLTESEQAAQCYIKYI 494 A +V L + +L + +A + + + Sbjct: 426 LDALEKIKAIGNEVTVDKWEPLLNNLGHVCRKLKKYAEALDYHRQAL 472 Score = 55.6 bits (132), Expect = 7e-08, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 36/79 (45%) Query: 366 GAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRA 425 +GH ++K + A+ +R A+ + ++ + +G + ++ + Y+ A Sbjct: 446 PLLNNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTA 505 Query: 426 HQLRPNDSRMLVALGECYE 444 LR +D+ + LG C E Sbjct: 506 LGLRRDDTFSVTMLGHCIE 524 >3ZN3-A nrPDB Length = 291 Score = 324 bits (831), Expect = 6e-89, Method: Composition-based stats. Identities = 90/282 (31%), Positives = 132/282 (46%), Gaps = 16/282 (5%) Query: 29 LREIKKQLLLIAGLTRERGLLHSSKWSAELA----------FSLPALPLAELQPPPPITE 78 LREI+ LL ERGL+++ +W+AE+ + P E P + Sbjct: 3 LREIRNCLLKCISECSERGLVYAVRWAAEMLNGMNPIEMEHIPFSSTPTGEFDLDPDMAN 62 Query: 79 E---DAQDMDAYTLAKAYFDVKEYDRAAHFLHGCNSKKAYFLYMYSRYLSGEKKKDDETV 135 E + ++ + Y LAK+YFD KE++RAA+ L C S K+ FL +YS+YL+GEKK ++E Sbjct: 63 EKLLEVEEKNIYLLAKSYFDCKEFERAAYTLQNCKSSKSIFLRLYSKYLAGEKKSEEENE 122 Query: 136 DSLGPLEKGQVKNEALRELRVELSKKHQARELDGFGLYLYGVVLRKLDLVKEAIDVFVEA 195 L N + L H D + LYL GVV RK +AID Sbjct: 123 TLLNTNLTLSSTNREFYYISEVLESLHYQGNKDPYLLYLSGVVYRKRKQDSKAIDFLKSC 182 Query: 196 THVLPLHWGAWLELCNLITDKEMLKFL--SLPDT-WMKEFFLAHIYTELQLIEEALQKYQ 252 P W AWLEL I E L + LP T M + F + EL + + + Sbjct: 183 VLKAPFFWSAWLELSLSIDSLETLTTVVSQLPSTHIMTKIFYVYASHELHQVNSSAYEKL 242 Query: 253 NLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDP 294 ++ F S Y+ +Q A+ ++ RD D+A S+F + DP Sbjct: 243 AEAEIIFPNSRYLKTQRALLTYDSRDFDEAESLFENILTNDP 284 >5G04-F nrPDB Length = 824 Score = 244 bits (623), Expect = 7e-65, Method: Composition-based stats. Identities = 74/262 (28%), Positives = 133/262 (50%), Gaps = 9/262 (3%) Query: 261 KSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKSELSYLA 320 + +++ QI AY + + +A IF+E+R+ + YR+E M+ +S L+ LS L+ Sbjct: 497 NTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLS 556 Query: 321 HNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKN 380 +L ++DK E C GN +SL+ +H+ A +FQRA++++P Y A+TL+GHE++ + Sbjct: 557 KDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEE 616 Query: 381 TSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALG 440 A+ +R+AI VN R Y AWYGLG Y + ++++A + P S +L +G Sbjct: 617 LDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIG 676 Query: 441 ECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYIKYIQDIYSC 500 L + +A +A + + A + A + Y +Q++ Sbjct: 677 VVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVL-------FANEKYKSALQELEEL 729 Query: 501 GEIVEHLEESTAFRYLAQYYFK 522 +IV +ES + + + Y K Sbjct: 730 KQIVP--KESLVYFLIGKVYKK 749 Score = 71.0 bits (172), Expect = 2e-12, Method: Composition-based stats. Identities = 47/288 (16%), Positives = 96/288 (33%), Gaps = 8/288 (2%) Query: 185 VKEAIDVFVEA-THVLPLHW------GAWLELCNLITDKEMLKFLSLPDTWMKEFFLAHI 237 KEAI++ +H W A+ EL + + + + + + E + Sbjct: 481 CKEAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYS 540 Query: 238 YTELQLIEE-ALQKYQNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYR 296 T L ++ AL + S + R+ D A+ F + DP Sbjct: 541 TTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNY 600 Query: 297 IENMDTFSNLLYVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQR 356 + + + N ++ +G Y + + A ++FQ+ Sbjct: 601 AYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQK 660 Query: 357 ALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPF 416 AL +NP+ +G +K + A+ AI ++ ++ + + Sbjct: 661 ALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYK 720 Query: 417 YCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGD 464 L Q+ P +S + +G+ Y+KL Q A + A + Sbjct: 721 SALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDP 768 Score = 38.6 bits (88), Expect = 0.008, Method: Composition-based stats. Identities = 37/202 (18%), Positives = 69/202 (34%), Gaps = 27/202 (13%) Query: 83 DMDAYTLAKAYFDVKEYDRAAHFL--HGCNSKKAYFLYMYSRYLSGEKKKDDETVDSLGP 140 + + LA Y+ + +A L H C + + +YL + D + Sbjct: 38 EEALFLLATCYYRSGKAYKAYRLLKGHSCTTPQ-------CKYLLAKCCVDLSKLAEGEQ 90 Query: 141 LEKGQVKNEALRELRVELSKKHQARELDGFGLYLYGVVLRKLDLVKEAIDVFVEATHVLP 200 + G V N+ + + F L L G V K D + + + + ++ + P Sbjct: 91 ILSGGVFNKQKSHDDIVTE----FGDSACFTLSLLGHVYCKTDRLAKGSECYQKSLSLNP 146 Query: 201 LHWGAWLELCNLITD---KEMLKFLSLPD----------TWMKEFFLAHIYTELQLIEEA 247 W + LC + + KF SL + T + L+H E L E Sbjct: 147 FLWSPFESLCEIGEKPDPDQTFKFTSLQNFSNCLPNSCTTQVPNHSLSHRQPETVLTETP 206 Query: 248 LQKYQNLI-DVGFSKSSYIVSQ 268 + ++ S S Y ++ Sbjct: 207 QDTIELNRLNLESSNSKYSLNT 228 Score = 35.2 bits (79), Expect = 0.078, Method: Composition-based stats. Identities = 19/154 (12%), Positives = 49/154 (31%), Gaps = 16/154 (10%) Query: 268 QIAVAYHNIRDIDKALSIFNELRKQDPYRI---------ENMDTFSNLLYVRSMKSELSY 318 Q Y + A ++ E+ ++ + + + L + Y Sbjct: 14 QALNHYAYRDAVFLAERLYAEVHSEEALFLLATCYYRSGKAYKAYRLLKGHSCTTPQCKY 73 Query: 319 LAHNLC-EIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYME 377 L C ++ K + G ++ + H+ + +L+GH Y + Sbjct: 74 LLAKCCVDLSKLAEGEQILSGGVFNKQKSHDDIV------TEFGDSACFTLSLLGHVYCK 127 Query: 378 MKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEI 411 + + Y+ ++ +N + + L + E Sbjct: 128 TDRLAKGSECYQKSLSLNPFLWSPFESLCEIGEK 161 Score = 28.2 bits (61), Expect = 9.1, Method: Composition-based stats. Identities = 14/106 (13%), Positives = 29/106 (27%), Gaps = 16/106 (15%) Query: 390 HAIEVNKRDY----RAWYGLGQTYEILKMPFYCLYYYRRAH--------QLRPNDSRMLV 437 A + K + Y L + L + Sbjct: 56 KAYRLLKGHSCTTPQCKYLLAKCCVDLSKLAEGEQILSGGVFNKQKSHDDIVTEFGDSAC 115 Query: 438 A----LGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQ 479 LG Y K ++L + +CY ++ ++ L ++ E+ Sbjct: 116 FTLSLLGHVYCKTDRLAKGSECYQKSLSLNPFLWSPFESLCEIGEK 161 >5G04-X nrPDB Length = 599 Score = 210 bits (535), Expect = 1e-54, Method: Composition-based stats. Identities = 77/376 (20%), Positives = 138/376 (36%), Gaps = 20/376 (5%) Query: 129 KKDDETVDSLGPLEKGQVKNEALRELRVELSKKHQARELDGFGLYLYGVVLRKLDLVKEA 188 K+D + + L + Q + + + L+ ++ + + Y VLR+ L +A Sbjct: 150 KQDKDAIAILDGIPSRQRTPK----INMMLANLYKKAGQERPSVTSYKEVLRQCPLALDA 205 Query: 189 IDVFVEATHVLPLHWGAWLELCNLITDKEMLKFLSLPDTWMKEFFLAHIYTELQLIEE-- 246 I + + + N+I L +LS+ W+K + H + I Sbjct: 206 ILGLLSLSVKGAEVASMTM---NVIQTVPNLDWLSV---WIKAYAFVHTGDNSRAISTIC 259 Query: 247 ALQKYQNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNL 306 +L+K L D + ++ +A Y D ++ F + + DPY I+ MD + L Sbjct: 260 SLEKKSLLRD-----NVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYL 314 Query: 307 LYVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYF-QRALKLNPRYL 365 L ++ L L I E V G +S S+ ALY +A++LN + Sbjct: 315 LAREGRLEDVENLGCRLFNISDQHAEPWVVSG-CHSFYSKRYSRALYLGAKAIQLNSNSV 373 Query: 366 GAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRA 425 A L G M AI +R AI + + GL + Y + Sbjct: 374 QALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNV 433 Query: 426 HQLRPNDSRMLVALGE-CYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESE 484 ++ +++ L L C E +AK +A A+VK A+L + + E Sbjct: 434 YKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYE 493 Query: 485 QAAQCYIKYIQDIYSC 500 + + C Sbjct: 494 DGIALLRNALANQSDC 509 >5A01-A nrPDB Length = 710 Score = 163 bits (413), Expect = 2e-40, Method: Composition-based stats. Identities = 38/187 (20%), Positives = 81/187 (43%), Gaps = 13/187 (6%) Query: 296 RIENMDTFSNLLYVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQ 355 ++++ +N+ + E + L E+ + + + + ++A ++++ Sbjct: 6 HADSLNNLANIKREQGYIEEATRLYLKALEVFPDFAAAHSNLASVLQQQGKLKEALMHYK 65 Query: 356 RALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMP 415 A+++ P + A++ MG+ E+++ S A+Q Y AI++N A L ++ Sbjct: 66 EAIRIQPTFADAYSNMGNTLKELQDVSGALQCYTRAIQINPAFADAHSNLASIHKDSGNI 125 Query: 416 FYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAK 475 + YR A +L+P+ L C Q+V C W Y D+ LV + Sbjct: 126 PEAIQSYRTALKLKPDFPDAYCNLAHCL----QIV----CDWTDY---DIRMKKLVSI-- 172 Query: 476 LHEQLTE 482 + EQL + Sbjct: 173 VTEQLEK 179 Score = 89.9 bits (221), Expect = 3e-18, Method: Composition-based stats. Identities = 26/134 (19%), Positives = 50/134 (37%) Query: 362 PRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYY 421 + + + + E A + Y A+EV A L + L + Sbjct: 4 SNHADSLNNLANIKREQGYIEEATRLYLKALEVFPDFAAAHSNLASVLQQQGKLKEALMH 63 Query: 422 YRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLT 481 Y+ A +++P + +G ++L + A +CY RA + A LA +H+ Sbjct: 64 YKEAIRIQPTFADAYSNMGNTLKELQDVSGALQCYTRAIQINPAFADAHSNLASIHKDSG 123 Query: 482 ESEQAAQCYIKYIQ 495 +A Q Y ++ Sbjct: 124 NIPEAIQSYRTALK 137 Score = 50.2 bits (118), Expect = 2e-06, Method: Composition-based stats. Identities = 29/143 (20%), Positives = 52/143 (36%), Gaps = 1/143 (0%) Query: 234 LAHIYTELQLIEEALQKYQNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQD 293 LA+I E IEEA + Y ++V F + S +A + +AL + E + Sbjct: 13 LANIKREQGYIEEATRLYLKALEV-FPDFAAAHSNLASVLQQQGKLKEALMHYKEAIRIQ 71 Query: 294 PYRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALY 353 P + N L S +I+ + + + + +A Sbjct: 72 PTFADAYSNMGNTLKELQDVSGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIQS 131 Query: 354 FQRALKLNPRYLGAWTLMGHEYM 376 ++ ALKL P + A+ + H Sbjct: 132 YRTALKLKPDFPDAYCNLAHCLQ 154 >5LVV-A nrPDB Length = 749 Score = 161 bits (408), Expect = 7e-40, Method: Composition-based stats. Identities = 37/187 (19%), Positives = 79/187 (42%), Gaps = 13/187 (6%) Query: 296 RIENMDTFSNLLYVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQ 355 ++++ +N+ + E L E+ + + + + ++A ++++ Sbjct: 29 HADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYK 88 Query: 356 RALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMP 415 A++++P + A++ MG+ EM++ A+Q Y AI++N A L ++ Sbjct: 89 EAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNI 148 Query: 416 FYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAK 475 + YR A +L+P+ L C Q+V C W Y D LV + Sbjct: 149 PEAIASYRTALKLKPDFPDAYCNLAHCL----QIV----CDWTDY---DERMKKLVSI-- 195 Query: 476 LHEQLTE 482 + +QL + Sbjct: 196 VADQLEK 202 Score = 90.2 bits (222), Expect = 2e-18, Method: Composition-based stats. Identities = 26/133 (19%), Positives = 51/133 (38%) Query: 363 RYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYY 422 + + + + E N A++ YR A+EV A L + L +Y Sbjct: 28 THADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHY 87 Query: 423 RRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTE 482 + A ++ P + +G +++ + A +CY RA + A LA +H+ Sbjct: 88 KEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGN 147 Query: 483 SEQAAQCYIKYIQ 495 +A Y ++ Sbjct: 148 IPEAIASYRTALK 160 >1W3B-A nrPDB Length = 388 Score = 145 bits (366), Expect = 4e-35, Method: Composition-based stats. Identities = 62/333 (18%), Positives = 118/333 (35%), Gaps = 27/333 (8%) Query: 163 QARELDGFGLYLYGVVLRKLDLVKEAIDVFVEATHVLPLHWGAWLELCNLITDKEMLKFL 222 Q + G L L + + L + A A PL A+ L N+ ++ L Sbjct: 28 QEPDNTGVLLLLSSIHFQCRRLDRSA-HFSTLAIKQNPLLAEAYSNLGNVYKERGQL--- 83 Query: 223 SLPDTWMKEFFLAHIYTELQLIEEALQKYQNLIDVGFSKSSYIVSQIAVAYHNIRDIDKA 282 + + H L+L + + Y NL + D++ A Sbjct: 84 --------QEAIEHYRHALRLKPDFIDGYINLAAALVA---------------AGDMEGA 120 Query: 283 LSIFNELRKQDPYRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYS 342 + + + +P NLL E E +G ++ Sbjct: 121 VQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFN 180 Query: 343 LRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAW 402 + + A +F++A+ L+P +L A+ +G+ E + A+ AY A+ ++ Sbjct: 181 AQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVH 240 Query: 403 YGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAV 462 L Y + + YRRA +L+P+ L ++ + EA+ CY A + Sbjct: 241 GNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRL 300 Query: 463 GDVEKMALVKLAKLHEQLTESEQAAQCYIKYIQ 495 +L LA + + E+A + Y K ++ Sbjct: 301 CPTHADSLNNLANIKREQGNIEEAVRLYRKALE 333 Score = 110 bits (274), Expect = 2e-24, Method: Composition-based stats. Identities = 49/314 (15%), Positives = 107/314 (34%), Gaps = 10/314 (3%) Query: 176 GVVLRKLDLVKEAIDVFVEATHVLPLHWGAWLELCNLITD--------KEMLKFLSL-PD 226 G V ++ ++EAI+ + A + P ++ L + + + L PD Sbjct: 74 GNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPD 133 Query: 227 TWMKEFFLAHIYTELQLIEEALQKYQNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIF 286 + L ++ L +EEA Y I+ + S + ++ +I A+ F Sbjct: 134 LYCVRSDLGNLLKALGRLEEAKACYLKAIETQ-PNFAVAWSNLGCVFNAQGEIWLAIHHF 192 Query: 287 NELRKQDPYRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQ 346 + DP ++ N+L + + + Y + Sbjct: 193 EKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGL 252 Query: 347 HEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLG 406 + A ++RA++L P + A+ + + E + + A Y A+ + + L Sbjct: 253 IDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLA 312 Query: 407 QTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVE 466 + YR+A ++ P + L ++ +L EA Y A + Sbjct: 313 NIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTF 372 Query: 467 KMALVKLAKLHEQL 480 A + +++ Sbjct: 373 ADAYSNMGNTLKEM 386 Score = 109 bits (273), Expect = 3e-24, Method: Composition-based stats. Identities = 39/221 (17%), Positives = 89/221 (40%) Query: 274 HNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDKYRVET 333 + D + A +L +Q+P + S++ + ++ + + + E Sbjct: 10 YQAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEA 69 Query: 334 CCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIE 393 +GN Y R Q ++A +++ AL+L P ++ + + + + A+QAY A++ Sbjct: 70 YSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQ 129 Query: 394 VNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAK 453 N Y LG + L Y +A + +PN + LG + ++ A Sbjct: 130 YNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAI 189 Query: 454 KCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYIKYI 494 + +A + A + L + ++ ++A Y++ + Sbjct: 190 HHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRAL 230 Score = 83.3 bits (204), Expect = 3e-16, Method: Composition-based stats. Identities = 30/151 (19%), Positives = 53/151 (35%) Query: 345 SQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYG 404 E A + + + P G L+ + + + + AI+ N A+ Sbjct: 13 GDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSN 72 Query: 405 LGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGD 464 LG Y+ + +YR A +L+P+ + L + A + Y A Sbjct: 73 LGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNP 132 Query: 465 VEKMALVKLAKLHEQLTESEQAAQCYIKYIQ 495 L L + L E+A CY+K I+ Sbjct: 133 DLYCVRSDLGNLLKALGRLEEAKACYLKAIE 163 Score = 76.0 bits (185), Expect = 5e-14, Method: Composition-based stats. Identities = 41/214 (19%), Positives = 92/214 (42%), Gaps = 10/214 (4%) Query: 176 GVVLRKLDLVKEAIDVFVEATHVLPLHWGAWLELCNLITDKEM--------LKFLSL-PD 226 G V + AI F +A + P A++ L N++ + + L+ LSL P+ Sbjct: 176 GCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPN 235 Query: 227 TWMKEFFLAHIYTELQLIEEALQKYQNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIF 286 + LA +Y E LI+ A+ Y+ I++ +A A + +A + Sbjct: 236 HAVVHGNLACVYYEQGLIDLAIDTYRRAIELQ-PHFPDAYCNLANALKEKGSVAEAEDCY 294 Query: 287 NELRKQDPYRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQ 346 N + P ++++ +N+ + E L E+ + + + + Sbjct: 295 NTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGK 354 Query: 347 HEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKN 380 ++A ++++ A++++P + A++ MG+ EM++ Sbjct: 355 LQEALMHYKEAIRISPTFADAYSNMGNTLKEMQD 388 Score = 48.3 bits (113), Expect = 1e-05, Method: Composition-based stats. Identities = 24/131 (18%), Positives = 44/131 (33%), Gaps = 3/131 (2%) Query: 371 MGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRP 430 + H + + AA + + L + + ++ A + P Sbjct: 5 LAHREYQAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNP 64 Query: 431 NDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCY 490 + LG Y++ QL EA + Y A + + LA + E A Q Y Sbjct: 65 LLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAY 124 Query: 491 IKYIQ---DIY 498 + +Q D+Y Sbjct: 125 VSALQYNPDLY 135 >6B85-J nrPDB Length = 223 Score = 135 bits (339), Expect = 5e-32, Method: Composition-based stats. Identities = 41/141 (29%), Positives = 68/141 (48%) Query: 328 KYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQA 387 ++G SL ++ AA +++A++L+P AW L+G ++K A +A Sbjct: 78 DVSALAYVMLGLLLSLLNRLSLAAEAYKKAIELDPNDALAWLLLGSVLEKLKRLDEAAEA 137 Query: 388 YRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLN 447 Y+ AIE+ D AW LG+ E L Y++A +L P D+ LG+ EKL Sbjct: 138 YKKAIELKPNDASAWKELGKVLEKLGRLDEAAEAYKKAIELDPEDAEAWKELGKVLEKLG 197 Query: 448 QLVEAKKCYWRAYAVGDVEKM 468 +L EA + Y +A + + Sbjct: 198 RLDEAAEAYKKAIELDPNDLE 218 Score = 134 bits (337), Expect = 9e-32, Method: Composition-based stats. Identities = 43/132 (32%), Positives = 69/132 (52%) Query: 364 YLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYR 423 A+ ++G + S A +AY+ AIE++ D AW LG E LK Y+ Sbjct: 80 SALAYVMLGLLLSLLNRLSLAAEAYKKAIELDPNDALAWLLLGSVLEKLKRLDEAAEAYK 139 Query: 424 RAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTES 483 +A +L+PND+ LG+ EKL +L EA + Y +A + + A +L K+ E+L Sbjct: 140 KAIELKPNDASAWKELGKVLEKLGRLDEAAEAYKKAIELDPEDAEAWKELGKVLEKLGRL 199 Query: 484 EQAAQCYIKYIQ 495 ++AA+ Y K I+ Sbjct: 200 DEAAEAYKKAIE 211 Score = 117 bits (292), Expect = 2e-26, Method: Composition-based stats. Identities = 30/118 (25%), Positives = 53/118 (44%) Query: 321 HNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKN 380 E+D ++G+ + ++AA +++A++L P AW +G ++ Sbjct: 105 KKAIELDPNDALAWLLLGSVLEKLKRLDEAAEAYKKAIELKPNDASAWKELGKVLEKLGR 164 Query: 381 TSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVA 438 A +AY+ AIE++ D AW LG+ E L Y++A +L PND Sbjct: 165 LDEAAEAYKKAIELDPEDAEAWKELGKVLEKLGRLDEAAEAYKKAIELDPNDLEHHHH 222 Score = 80.6 bits (197), Expect = 2e-15, Method: Composition-based stats. Identities = 28/208 (13%), Positives = 69/208 (33%), Gaps = 6/208 (2%) Query: 195 ATHVLPLHWGAWLELCNLITDKEMLKFLSLPDTWMKEFFLAHIYTELQLIEEALQKYQNL 254 + L W ++ ++ LS+ + + + E+ + Sbjct: 19 LVFAILLSAIIWYQITTNPDTSQIATLLSMQLLLIALMLVVIALLLSRQTEQVAE----- 73 Query: 255 IDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKS 314 + S+ + + + + A + + + DP ++L Sbjct: 74 -SIRRDVSALAYVMLGLLLSLLNRLSLAAEAYKKAIELDPNDALAWLLLGSVLEKLKRLD 132 Query: 315 ELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHE 374 E + E+ +G + ++AA +++A++L+P AW +G Sbjct: 133 EAAEAYKKAIELKPNDASAWKELGKVLEKLGRLDEAAEAYKKAIELDPEDAEAWKELGKV 192 Query: 375 YMEMKNTSAAIQAYRHAIEVNKRDYRAW 402 ++ A +AY+ AIE++ D Sbjct: 193 LEKLGRLDEAAEAYKKAIELDPNDLEHH 220 >4M57-A nrPDB Length = 726 Score = 102 bits (253), Expect = 6e-22, Method: Composition-based stats. Identities = 23/105 (21%), Positives = 50/105 (47%), Gaps = 6/105 (5%) Query: 234 LAHIYTELQLIEEALQKYQNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQD 293 LA Y EEA + + G +++ + + AY N+ +D+AL++F++++K Sbjct: 261 LAGTYARAGFFEEAARCLDTMASKGLLPNAFTYNTVMTAYGNVGKVDEALALFDQMKKTG 320 Query: 294 PYRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDKY----RVETC 334 + N++T++ +L + KS + + L E+ + T Sbjct: 321 --FVPNVNTYNLVLGMLGKKSRFTVMLEMLGEMSRSGCTPNRVTW 363 >5NNP-A nrPDB Length = 745 Score = 67.5 bits (163), Expect = 2e-11, Method: Composition-based stats. Identities = 35/241 (14%), Positives = 80/241 (33%), Gaps = 9/241 (3%) Query: 263 SYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKSELSYLAHN 322 + + + Y + + + L ++ K++P + M + +L + E LA Sbjct: 11 ANLFRTVIRHYED-KQYKRGLKAAEQILKKNPKHGDTMSMKALILNAQGKTEEAFALAKE 69 Query: 323 LCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTS 382 ID V G Y ++A ++ ALKL P + ++M++ + Sbjct: 70 ALTIDMKSYICWHVYGILYRTNKNFDEAIKAYKFALKLEPESHQIQRDLAVLQIQMRDYA 129 Query: 383 AAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLY---YYRRAHQLRP-----NDSR 434 +Q+ + ++ + + W L Y + + Y ++ P S Sbjct: 130 GYVQSRLNMLKARPQIRQNWTALAIAYHLEGNLEKAEHILTTYEKSLTTPPPKTDLEHSE 189 Query: 435 MLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYIKYI 494 L+ + + A + + A +L ++AA+ Y + Sbjct: 190 ALLYKNTIIAERGDIERALQHLETDCKHCLDRLAVMELRASYLSKLARKDEAAKAYRALL 249 Query: 495 Q 495 Sbjct: 250 D 250 Score = 43.2 bits (100), Expect = 4e-04, Method: Composition-based stats. Identities = 35/238 (14%), Positives = 67/238 (28%), Gaps = 14/238 (5%) Query: 270 AVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDKY 329 + Y ++ D+A+ + K +P E+ +L ++ + + + + K Sbjct: 85 GILYRTNKNFDEAIKAYKFALKLEP---ESHQIQRDLAVLQIQMRDYAGYVQSRLNMLKA 141 Query: 330 RVE---TCCVIGNYYSLRSQHEKA---ALYFQRALKLNP-----RYLGAWTLMGHEYMEM 378 R + + Y L EKA ++++L P + A E Sbjct: 142 RPQIRQNWTALAIAYHLEGNLEKAEHILTTYEKSLTTPPPKTDLEHSEALLYKNTIIAER 201 Query: 379 KNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVA 438 + A+Q + L YR P Sbjct: 202 GDIERALQHLETDCKHCLDRLAVMELRASYLSKLARKDEAAKAYRALLDRNPEHMDYYKG 261 Query: 439 LGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYIKYIQD 496 L + EA+K + YA A +L A+ Y+ + D Sbjct: 262 LISALDISADDEEAQKAVYDEYAAKYPRSDAAKRLPLNFLSGERFRTTAKAYLTLMFD 319 Score = 34.8 bits (78), Expect = 0.11, Method: Composition-based stats. Identities = 33/207 (15%), Positives = 68/207 (32%), Gaps = 23/207 (11%) Query: 245 EEALQKYQNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYR--IENMDT 302 +EA + Y+ L+D Y I+ + D + ++++E + P + + Sbjct: 239 DEAAKAYRALLDRNPEHMDYYKGLISALDISADDEEAQKAVYDEYAAKYPRSDAAKRLPL 298 Query: 303 FSNLLYVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEK----AALYFQRAL 358 + L R + +YL DK T + + YS + E A Y + Sbjct: 299 -NFLSGERFRTTAKAYLTLMF---DKGVPSTFANLKHLYSDSFKKETLASLAEEYLNEYV 354 Query: 359 KLNPRYLGA-------------WTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGL 405 P A + + Y ++ + A++ AIE++ ++ Sbjct: 355 NARPSDNQADGDGSKGKGAALYYLAQHYNYYMSRDLTRALEYVEKAIELDPKNVDFHMTK 414 Query: 406 GQTYEILKMPFYCLYYYRRAHQLRPND 432 + ++ A L P D Sbjct: 415 ARIFKHQGDLAKAAETMDYARSLDPKD 441 >5JJT-A nrPDB Length = 479 Score = 61.7 bits (148), Expect = 8e-10, Method: Composition-based stats. Identities = 25/104 (24%), Positives = 47/104 (45%) Query: 346 QHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGL 405 ++ A + +A++LN W + +++ +AIQ AIEV+ R + +Y Sbjct: 24 KYSSAIDLYTKAIELNSNNAVYWANRAFAHTKLEEYGSAIQDASKAIEVDSRYSKGYYRR 83 Query: 406 GQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQL 449 G Y + L +++ +L PND L EC + + +L Sbjct: 84 GAAYLAMGKFKDALKDFQQVKRLSPNDPDATRKLKECEKAVMKL 127 Score = 41.3 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 19/105 (18%), Positives = 41/105 (39%) Query: 380 NTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVAL 439 S+AI Y AIE+N + W + L+ + +A ++ S+ Sbjct: 24 KYSSAIDLYTKAIELNSNNAVYWANRAFAHTKLEEYGSAIQDASKAIEVDSRYSKGYYRR 83 Query: 440 GECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESE 484 G Y + + +A K + + + + A KL + + + + + Sbjct: 84 GAAYLAMGKFKDALKDFQQVKRLSPNDPDATRKLKECEKAVMKLK 128 >5DSE-A nrPDB Length = 837 Score = 59.4 bits (142), Expect = 5e-09, Method: Composition-based stats. Identities = 21/133 (15%), Positives = 38/133 (28%) Query: 331 VETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRH 390 + Y + +A Q A L P + G + A + Y Sbjct: 690 AQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQIAELRGSMDEARRWYEE 749 Query: 391 AIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLV 450 A+ ++ ++ L L R A Q+ + LGE + Sbjct: 750 ALAISPTHVKSMQRLALILHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDA 809 Query: 451 EAKKCYWRAYAVG 463 A +C+ A + Sbjct: 810 AATECFLTALELE 822 Score = 59.0 bits (141), Expect = 6e-09, Method: Composition-based stats. Identities = 20/126 (15%), Positives = 47/126 (37%) Query: 310 RSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWT 369 +E + + + G LR ++A +++ AL ++P ++ + Sbjct: 703 IGKPAEATACTQEAANLFPMSHNVLYMRGQIAELRGSMDEARRWYEEALAISPTHVKSMQ 762 Query: 370 LMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLR 429 + ++ S A + R A++VN + W GLG+ + + A +L Sbjct: 763 RLALILHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALELE 822 Query: 430 PNDSRM 435 + + Sbjct: 823 ASSPAV 828 Score = 45.9 bits (107), Expect = 5e-05, Method: Composition-based stats. Identities = 23/193 (11%), Positives = 54/193 (27%), Gaps = 16/193 (8%) Query: 257 VGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKSEL 316 + +S + + +A + K F+ L + Sbjct: 351 ISLQSASVVYDLLTIALGRRGQYEMLSECLERAMKFAFEEFHLWYQFALSLMAAGKSARA 410 Query: 317 SYLAHNLCEIDKYRV-ETCCVIGNYYSLRSQHEKAALYFQRALKL-NPRY---LGAWTLM 371 + + E+A + + + + + + Sbjct: 411 VKVLKECIRLKPDDATIPLLAAKLCMGSLHWLEEAEKFAKTVVDVGEKTSEFKAKGYLAL 470 Query: 372 G---------HEYMEMKNT--SAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLY 420 G M+ A+ A++ A ++ D++A + L I + L Sbjct: 471 GLTYSLQATDASLRGMQEVLQRKALLAFQRAHSLSPTDHQAAFYLALQLAISRQIPEALG 530 Query: 421 YYRRAHQLRPNDS 433 Y R+A QL+ +D+ Sbjct: 531 YVRQALQLQGDDA 543 >6FO1-G nrPDB Length = 665 Score = 59.4 bits (142), Expect = 5e-09, Method: Composition-based stats. Identities = 38/258 (14%), Positives = 82/258 (31%), Gaps = 14/258 (5%) Query: 238 YTELQLIEEALQKYQNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYRI 297 Y + +EA+ Y +D + + + A AY ++ A S N + Sbjct: 143 YFKQGKYDEAIDCYTKGMDAD-PYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYT 201 Query: 298 ENMDTFSNLLYVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHE--------- 348 + + E + E++ E + + E Sbjct: 202 KAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADI 261 Query: 349 --KAALYFQRALKLNPRYLGAWTLM--GHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYG 404 K+ ++ ++ A + G+ + + AI+ Y I + + Sbjct: 262 VIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPAN 321 Query: 405 LGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGD 464 Y ++ +A L + S+ G L +L EAK+ + + Sbjct: 322 RAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEP 381 Query: 465 VEKMALVKLAKLHEQLTE 482 K A+ +L+K+ ++L E Sbjct: 382 GNKQAVTELSKIKKELIE 399 Score = 49.4 bits (116), Expect = 4e-06, Method: Composition-based stats. Identities = 32/179 (17%), Positives = 63/179 (35%), Gaps = 4/179 (2%) Query: 358 LKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFY 417 + ++ + G++Y + AI Y ++ + + Y LK Sbjct: 126 IHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAV 185 Query: 418 CLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLH 477 A L + ++ G L +L EAKK Y R + A +L K+ Sbjct: 186 AESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKIS 245 Query: 478 EQLTESEQA----AQCYIKYIQDIYSCGEIVEHLEESTAFRYLAQYYFKCKLWDEASTC 532 + L E + A IK + E ++ +++ + + +FK ++ A C Sbjct: 246 QALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIEC 304 Score = 43.2 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 37/236 (15%), Positives = 84/236 (35%), Gaps = 23/236 (9%) Query: 260 SKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKSELSYL 319 S+ + ++ + Y D+A+ + + DPY + T Y R K ++ Sbjct: 130 SQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYN-PVLPTNRASAYFRLKKFAVAES 188 Query: 320 AHNL-CEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEM 378 NL +++ + G + E+A ++R L+L P A E+ Sbjct: 189 DCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEA-------TNEL 241 Query: 379 KNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVA 438 + S A+ + ++ ++ + ++ E + ++A + Sbjct: 242 RKISQALASKENSY---PKEADI---VIKSTEGERKQIEAQQNKQQAISEK--------D 287 Query: 439 LGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYIKYI 494 G + K + A +CY R A + A + ++ + E+A + + I Sbjct: 288 RGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAI 343 >5AEM-A nrPDB Length = 447 Score = 58.7 bits (140), Expect = 7e-09, Method: Composition-based stats. Identities = 31/149 (20%), Positives = 55/149 (36%) Query: 344 RSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWY 403 R+ + A F +K + R A+ +G Y + ++ A +N D+ W Sbjct: 22 RNDLQVAERLFNEVIKKDARNFAAYETLGDIYQLQGRLNDCCNSWFLAAHLNASDWEFWK 81 Query: 404 GLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVG 463 + L +Y + R L P + + Y+K QL A + R Y Sbjct: 82 IVAILSADLDHVRQAIYCFSRVISLNPMEWESIYRRSMLYKKTGQLARALDGFQRLYMYN 141 Query: 464 DVEKMALVKLAKLHEQLTESEQAAQCYIK 492 + L +LA L+ E + + Y+K Sbjct: 142 PYDANILRELAILYVDYDRIEDSIELYMK 170 Score = 57.1 bits (136), Expect = 2e-08, Method: Composition-based stats. Identities = 31/182 (17%), Positives = 70/182 (38%), Gaps = 2/182 (1%) Query: 308 YVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGA 367 +VR+ L + + + D +G+ Y L+ + + A LN Sbjct: 20 FVRNDLQVAERLFNEVIKKDARNFAAYETLGDIYQLQGRLNDCCNSWFLAAHLNASDWEF 79 Query: 368 WTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQ 427 W ++ ++ + AI + I +N ++ + Y Y+ L ++R + Sbjct: 80 WKIVAILSADLDHVRQAIYCFSRVISLNPMEWESIYRRSMLYKKTGQLARALDGFQRLYM 139 Query: 428 LRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAA 487 P D+ +L L Y +++ ++ + Y + + + A+ LA L L S++ + Sbjct: 140 YNPYDANILRELAILYVDYDRIEDSIELYMKVFNANVERREAI--LAALENALDSSDEES 197 Query: 488 QC 489 Sbjct: 198 AA 199 Score = 35.9 bits (81), Expect = 0.056, Method: Composition-based stats. Identities = 15/84 (17%), Positives = 32/84 (38%), Gaps = 1/84 (1%) Query: 365 LGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNK-RDYRAWYGLGQTYEILKMPFYCLYYYR 423 + + AI + + + + R + L + Y+ ++ +Y Sbjct: 348 ADLYFEAATALTRAEKYKEAIDFFTPLLSLEEWRTTDVFKPLARCYKEIESYETAKEFYE 407 Query: 424 RAHQLRPNDSRMLVALGECYEKLN 447 A + P+D + V+L E Y +LN Sbjct: 408 LAIKSEPDDLDIRVSLAEVYYRLN 431 Score = 33.2 bits (74), Expect = 0.34, Method: Composition-based stats. Identities = 26/149 (17%), Positives = 50/149 (33%), Gaps = 9/149 (6%) Query: 274 HNIRDIDKALSIFNELRKQDPYRIENMDTFSNL---LYVRSMKSELSYLAHNLC---EID 327 + R S F+ L + + N+ + L + + + L H C E Sbjct: 287 FDNRRFKN--STFDSLLAAEKEKSYNIPIDIRVRLGLLRLNTDNLVEALNHFQCLYDETF 344 Query: 328 KYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNP-RYLGAWTLMGHEYMEMKNTSAAIQ 386 + + ++++A +F L L R + + Y E+++ A + Sbjct: 345 SDVADLYFEAATALTRAEKYKEAIDFFTPLLSLEEWRTTDVFKPLARCYKEIESYETAKE 404 Query: 387 AYRHAIEVNKRDYRAWYGLGQTYEILKMP 415 Y AI+ D L + Y L P Sbjct: 405 FYELAIKSEPDDLDIRVSLAEVYYRLNDP 433 >2GW1-A nrPDB Length = 514 Score = 57.1 bits (136), Expect = 2e-08, Method: Composition-based stats. Identities = 63/380 (16%), Positives = 121/380 (31%), Gaps = 17/380 (4%) Query: 177 VVLRKLDLVKEAIDVFVEATHVLPLHWGAWLELCNLITDKEMLKFLSLPDTWMKEFFLAH 236 + + +L K+A+ E + EL + K +LP F Sbjct: 111 EPMLERNLNKQAMSKLKEKFGDIDTATATPTELSTQPAKERKDKQENLPSVTSMASFFGI 170 Query: 237 IYTELQLIEEALQKYQNLIDVGFSKSSYIVSQIAVAYHNIRD--IDKALSIFNELRKQDP 294 EL N D + + + ++ D KA +F E ++ Sbjct: 171 FKPELTFAN---YDESNEADKELMNGLSNLYKRSPESYDKADESFTKAARLFEEQLDKNN 227 Query: 295 YRIENMDTFSNLLYVRSMKSELSY--LA-----HNLCEIDKYRVETCCVIGNYYSLRSQH 347 + + + L + L L E+ RV + + + R+ Sbjct: 228 EDEKLKEKLAISLEHTGIFKFLKNDPLGAHEDIKKAIELFP-RVNSYIYMALIMADRNDS 286 Query: 348 EKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQ 407 + YF +ALKL+ + G ++N A + + A E++ + + L Sbjct: 287 TEYYNYFDKALKLDSNNSSVYYHRGQMNFILQNYDQAGKDFDKAKELDPENIFPYIQLAC 346 Query: 408 TYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEK 467 C + A + P + E N +A K Y A + + Sbjct: 347 LAYRENKFDDCETLFSEAKRKFPEAPEVPNFFAEILTDKNDFDKALKQYDLAIELENKLD 406 Query: 468 MALVKLAKLHEQLTESEQ--AAQCYIKYIQDIYSCGEIVEHLEESTAFRYLAQYYFKCKL 525 V +A L + T + + +I+ + ++ E++ LAQ + + Sbjct: 407 GIYVGIAPLVGKATLLTRNPTVENFIEATNLLEKASKLDPRSEQAKI--GLAQMKLQQED 464 Query: 526 WDEASTCAQKCCAFNDTREE 545 DEA T ++ T EE Sbjct: 465 IDEAITLFEESADLARTMEE 484 Score = 39.4 bits (90), Expect = 0.005, Method: Composition-based stats. Identities = 18/89 (20%), Positives = 31/89 (34%), Gaps = 1/89 (1%) Query: 398 DYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYW 457 A G + K + YY A +L+ D L CY + L + + Sbjct: 5 YALALKDKGNQFFRNKKYDDAIKYYNWALELK-EDPVFYSNLSACYVSVGDLKKVVEMST 63 Query: 458 RAYAVGDVEKMALVKLAKLHEQLTESEQA 486 +A + L++ A +E L + A Sbjct: 64 KALELKPDYSKVLLRRASANEGLGKFADA 92 >5FZQ-A nrPDB Length = 131 Score = 56.7 bits (135), Expect = 3e-08, Method: Composition-based stats. Identities = 16/92 (17%), Positives = 37/92 (40%) Query: 337 IGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNK 396 + N + + E+A Y ++A+ L+P + + + + + AI+ R A+ ++ Sbjct: 11 LANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLANLLAQEGKAEEAIKYMRKAVSLDP 70 Query: 397 RDYRAWYGLGQTYEILKMPFYCLYYYRRAHQL 428 + + L + Y R+A L Sbjct: 71 NNIKTLSNLAVLLAQEGKAEEAIKYMRKAVSL 102 Score = 52.5 bits (124), Expect = 6e-07, Method: Composition-based stats. Identities = 18/106 (16%), Positives = 38/106 (35%) Query: 363 RYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYY 422 + + + + + AI+ R A+ ++ + + L + Y Sbjct: 3 NSIKTLSNLANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLANLLAQEGKAEEAIKYM 62 Query: 423 RRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKM 468 R+A L PN+ + L L + + EA K +A ++ D Sbjct: 63 RKAVSLDPNNIKTLSNLAVLLAQEGKAEEAIKYMRKAVSLIDKAAK 108 Score = 50.9 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 18/98 (18%), Positives = 39/98 (39%) Query: 297 IENMDTFSNLLYVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQR 356 I+ + +NLL E +D ++T + N + + E+A Y ++ Sbjct: 5 IKTLSNLANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLANLLAQEGKAEEAIKYMRK 64 Query: 357 ALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEV 394 A+ L+P + + + + AI+ R A+ + Sbjct: 65 AVSLDPNNIKTLSNLAVLLAQEGKAEEAIKYMRKAVSL 102 Score = 50.2 bits (118), Expect = 3e-06, Method: Composition-based stats. Identities = 22/95 (23%), Positives = 36/95 (37%) Query: 403 YGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAV 462 L + Y R+A L PN+ + L L + + EA K +A ++ Sbjct: 9 SNLANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLANLLAQEGKAEEAIKYMRKAVSL 68 Query: 463 GDVEKMALVKLAKLHEQLTESEQAAQCYIKYIQDI 497 L LA L Q ++E+A + K + I Sbjct: 69 DPNNIKTLSNLAVLLAQEGKAEEAIKYMRKAVSLI 103 Score = 42.1 bits (97), Expect = 6e-04, Method: Composition-based stats. Identities = 18/100 (18%), Positives = 37/100 (37%) Query: 261 KSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKSELSYLA 320 S +S +A ++A+ + DP I+ + +NLL E Sbjct: 3 NSIKTLSNLANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLANLLAQEGKAEEAIKYM 62 Query: 321 HNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKL 360 +D ++T + + + E+A Y ++A+ L Sbjct: 63 RKAVSLDPNNIKTLSNLAVLLAQEGKAEEAIKYMRKAVSL 102 Score = 31.3 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 26/64 (40%) Query: 431 NDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCY 490 N + L L + + EA K +A ++ L LA L Q ++E+A + Sbjct: 3 NSIKTLSNLANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLANLLAQEGKAEEAIKYM 62 Query: 491 IKYI 494 K + Sbjct: 63 RKAV 66 >6C95-A nrPDB Length = 866 Score = 56.7 bits (135), Expect = 3e-08, Method: Composition-based stats. Identities = 39/250 (15%), Positives = 78/250 (31%), Gaps = 14/250 (5%) Query: 254 LIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPY--RIENMDTFSNLLYVRS 311 + V + + + + + L ++ + E + L Sbjct: 1 MPAVSLPPKENALFKRILRCYEHKQYRNGLKFCKQILSNPKFAEHGETLAMKGLTLNCLG 60 Query: 312 MKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLM 371 K E L D V G ++++A ++ ALK + L + Sbjct: 61 KKEEAYELVRRGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDL 120 Query: 372 GHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYC---LYYYRRAHQL 428 ++M++ + +++ +W G Y +L+ L +R+ Q Sbjct: 121 SLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQT 180 Query: 429 RPNDSRMLVALGECYEKLNQLVEAKKCYWRA------YAVGDVEKMALVKL-AKLHEQLT 481 P+ E NQ++ Y A Y +K+A+ + +L QL Sbjct: 181 SPDKVD--YEYSELLLYQNQVLREAGLYREALEHLCTYEKQICDKLAVEETKGELLLQLC 238 Query: 482 ESEQAAQCYI 491 E AA Y Sbjct: 239 RLEDAADVYR 248 Score = 40.9 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 65/428 (15%), Positives = 129/428 (30%), Gaps = 69/428 (16%) Query: 90 AKAYFDVKEYDRAAHFLHGCNSKKA---YFL-YMYSRYLSGEKKKDDETVDSLGPLEKGQ 145 A AY +++Y+ AA L + + Y YS L + + E LE Sbjct: 155 AIAYHLLEDYEMAAKILEEFRKTQQTSPDKVDYEYSELLLYQNQVLREAGLYREALEHLC 214 Query: 146 VKNEALRELRVELSKKHQARELDGFGLYLYGVVLRKLDLVKEAIDVFVEATHVLPLHWGA 205 + + + K G +L +L +++A DV+ P +W Sbjct: 215 TYEKQICDKLAVEETK--------------GELLLQLCRLEDAADVYRGLQERNPENWAY 260 Query: 206 WLELCNLITDKEMLKFLSLPDTWMKEFFLAHIYTELQLIEEALQKYQNLIDVGFSKSSYI 265 + L + ML+ L + + ++ + Sbjct: 261 YKGLEKALKPANMLERLKIYEEAWTKY----------------------------PRGLV 292 Query: 266 VSQIAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKSELSYLAHNLCE 325 ++ + + + + L F + + F+ L E + L Sbjct: 293 PRRLPLNFLSGEKFKECLDKFLRM----NFSKGCPPVFN-TLRSLYKDKEKVAIIEELVV 347 Query: 326 IDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLM--GHEYMEMKNTSA 383 + +++C L + ++ P W Y ++ S Sbjct: 348 GYETSLKSC-------RLFNPNDDGKE--------EPPTTLLWVQYYLAQHYDKIGQPSI 392 Query: 384 AIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECY 443 A++ AIE + + Y+ + A L D + + Sbjct: 393 ALEYINTAIESTPTLIELFLVKAKIYKHAGNIKEAARWMDEAQALDTADRFINSKCAKYM 452 Query: 444 EKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYIKYIQDIYSCGEI 503 K N + EA++ + G L ++ + Q TE QA + K+ + + C EI Sbjct: 453 LKANLIKEAEEMCSKFTREGTSAVENLNEMQCMWFQ-TECAQAYKAMNKFGEALKKCHEI 511 Query: 504 VEHLEEST 511 H E T Sbjct: 512 ERHFIEIT 519 >4JA9-A nrPDB Length = 488 Score = 55.6 bits (132), Expect = 6e-08, Method: Composition-based stats. Identities = 38/194 (19%), Positives = 76/194 (39%), Gaps = 10/194 (5%) Query: 330 RVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYR 389 R E N Y +E A ++ +A++LNP + Y+ + A+ Sbjct: 16 RAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDAT 75 Query: 390 HAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQL 449 AIE++K+ + +Y + L L Y +++PND + EC + + Q Sbjct: 76 RAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMKYQECSKIVKQ- 134 Query: 450 VEAKKCYWRAYAVGD-----VEKMALVKLAKLHEQLTESEQAAQCYIKYIQDIYSCGEIV 504 K + RA A + V+ + + + E + + I +++D+ + Sbjct: 135 ----KAFERAIAGDEHRRSVVDSLDIESMTIEDEYSGPKLEDGKVTITFMKDLMQWYKDQ 190 Query: 505 EHLEESTAFRYLAQ 518 + L A++ L Q Sbjct: 191 KKLHRKCAYQILVQ 204 >4G1T-A nrPDB Length = 472 Score = 52.1 bits (123), Expect = 7e-07, Method: Composition-based stats. Identities = 54/330 (16%), Positives = 112/330 (33%), Gaps = 41/330 (12%) Query: 233 FLAHIYTELQLIEEALQKY--------QNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALS 284 LA++ E AL+ Q D +S A Y+++ + Sbjct: 56 LLAYLKHLKGQNEAALECLRKAEELIQQEHADQAEIRSLVTWGNYAWVYYHMGRLSDVQI 115 Query: 285 IFNELRKQ-----DPYRIENMDTFSNLLYVR-----SMKSELSYLAHNLCEIDKYRVE-- 332 ++++ PYRIE+ + + R + E E Sbjct: 116 YVDKVKHVCEKFSSPYRIESPELDCEEGWTRLKCGGNQNERAKVCFEKALEKKPKNPEFT 175 Query: 333 TCCVIGNY-YSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYR-- 389 + I +Y + A ++A++LNP L+ + +M+ Sbjct: 176 SGLAIASYRLDNWPPSQNAIDPLRQAIRLNPDNQYLKVLLALKLHKMREEGEEEGEGEKL 235 Query: 390 --HAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYE-KL 446 A+E + Y P + ++A + PN++ + +G CY K+ Sbjct: 236 VEEALEKAPGVTDVLRSAAKFYRRKDEPDKAIELLKKALEYIPNNAYLHCQIGCCYRAKV 295 Query: 447 NQLVEAKKCYWRAYAVGDVEKMALVKL-AKLHEQLTESEQAAQCYIKYIQDIYSCGEIVE 505 Q++ ++ G K L++L L ++++A + + S + + Sbjct: 296 FQVMNLRE-------NGMYGKRKLLELIGHAVAHLKKADEANDNLFRVCSILASLHALAD 348 Query: 506 HLEESTAFRYLAQYYFKCKLWDEASTCAQK 535 EE A+YYF+ + E + A++ Sbjct: 349 QYEE-------AEYYFQKEFSKELTPVAKQ 371 >6AHD-N nrPDB Length = 941 Score = 51.3 bits (121), Expect = 1e-06, Method: Composition-based stats. Identities = 41/262 (15%), Positives = 86/262 (32%), Gaps = 17/262 (6%) Query: 240 ELQLIEEALQKYQNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYRIEN 299 L + +++ + G+ + + S I +I DI KA + +R+ +P+ Sbjct: 254 RLSQVSDSVSGQTVVDPKGYL--TDLNSMIPTHGGDINDIKKARLLLKSVRETNPHHPPA 311 Query: 300 MDTFSNLLYVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALK 359 + L V L E+ + + + A +A++ Sbjct: 312 WIASARLEEVTGKLQVARNLIMKGTEMCPKSEDVWLEA----ARLQPGDTAKAVVAQAVR 367 Query: 360 LNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCL 419 P+ + + + A + R A+E R W + L+ P Sbjct: 368 HLPQSVRIYI---RAAELETDIRAKKRVLRKALEHVPNSVRLWKAAVE----LEEPEDAR 420 Query: 420 YYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQ 479 RA + P + +AL +L A+K +A ++ + AKL E Sbjct: 421 IMLSRAVECCPTSVELWLALA----RLETYENARKVLNKARENIPTDRHIWITAAKLEEA 476 Query: 480 LTESEQAAQCYIKYIQDIYSCG 501 ++ + + I + + G Sbjct: 477 NGNTQMVEKIIDRAITSLRANG 498 Score = 44.4 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 31/180 (17%), Positives = 59/180 (32%), Gaps = 5/180 (2%) Query: 324 CEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYME--MKNT 381 + + E S ++E+A +A P A M +E N Sbjct: 635 FQANPNSEEIWLAAVKLESENDEYERARRLLAKARSSAPT---ARVFMKSVKLEWVQDNI 691 Query: 382 SAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGE 441 AA A+ + + W GQ E +M Y + + P+ + + + L Sbjct: 692 RAAQDLCEEALRHYEDFPKLWMMKGQIEEQKEMMEKAREAYNQGLKKCPHSTPLWLLLSR 751 Query: 442 CYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYIKYIQDIYSCG 501 EK+ QL A+ ++ ++ +L + A K +Q+ + G Sbjct: 752 LEEKIGQLTRARAILEKSRLKNPKNPGLWLESVRLEYRAGLKNIANTLMAKALQECPNSG 811 Score = 42.5 bits (98), Expect = 5e-04, Method: Composition-based stats. Identities = 34/243 (13%), Positives = 69/243 (28%), Gaps = 10/243 (4%) Query: 247 ALQKYQNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNL 306 A + L S I + ++A + + R P M + L Sbjct: 626 AARSILALAFQANPNSEEIWLAAVKLESENDEYERARRLLAKARSSAPTARVFMKS-VKL 684 Query: 307 LYVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLG 366 +V+ L + + + G + EKA + + LK P Sbjct: 685 EWVQDNIRAAQDLCEEALRHYEDFPKLWMMKGQIEEQKEMMEKAREAYNQGLKKCPHSTP 744 Query: 367 AWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAH 426 W L+ ++ + A + N ++ W + + +A Sbjct: 745 LWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESVRLEYRAGLKNIANTLMAKAL 804 Query: 427 QLRPNDSRMLVAL----GECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTE 482 Q PN + + + KKC +A+ KL ++T+ Sbjct: 805 QECPNSGILWSEAIFLEARPQRRTKSVDALKKC-----EHDPHVLLAVAKLFWSQRKITK 859 Query: 483 SEQ 485 + + Sbjct: 860 ARE 862 Score = 34.8 bits (78), Expect = 0.12, Method: Composition-based stats. Identities = 46/380 (12%), Positives = 114/380 (30%), Gaps = 50/380 (13%) Query: 154 LRVELSKKHQARELDGFGLYLYGVVLRKLDLVKEAIDVFVEATHVLPLHWGAWLELCNLI 213 +R + +A E + L+ + +L+ ++A + A P WL L L Sbjct: 386 IRAKKRVLRKALEHVPNSVRLWKAAV-ELEEPEDARIMLSRAVECCPTSVELWLALARL- 443 Query: 214 TDKEMLKFL------SLPDT---WMKEFFLAHIYTELQLIEEALQK-YQNLIDVGFSKSS 263 E + + ++P W+ L Q++E+ + + +L G + Sbjct: 444 ETYENARKVLNKARENIPTDRHIWITAAKLEEANGNTQMVEKIIDRAITSLRANGVEINR 503 Query: 264 YIVSQIAVAYHNIRDIDKALSIFNELR----KQDPYRIENMDTFSNLLYVRSMKSELSYL 319 Q A + ++ + +++ + M+ + + +++ + Sbjct: 504 EQWIQDAEECDRAGSVATCQAVMRAVIGIGIEEEDRKHTWMEDADSCVAHNALECARAIY 563 Query: 320 AHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMK 379 A+ L ++ + + E QRA+ P+ W + Sbjct: 564 AYAL-QVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHCPKAEVLWLMGAKSKWLAG 622 Query: 380 NTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRP--------- 430 + AA A + N W + +A P Sbjct: 623 DVPAARSILALAFQANPNSEEIWLAAVKLESENDEYERARRLLAKARSSAPTARVFMKSV 682 Query: 431 ------------------------NDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVE 466 + ++ + G+ E+ + +A++ Y + Sbjct: 683 KLEWVQDNIRAAQDLCEEALRHYEDFPKLWMMKGQIEEQKEMMEKAREAYNQGLKKCPHS 742 Query: 467 KMALVKLAKLHEQLTESEQA 486 + L++L E++ + +A Sbjct: 743 TPLWLLLSRLEEKIGQLTRA 762 Score = 30.9 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 50/369 (13%), Positives = 110/369 (29%), Gaps = 45/369 (12%) Query: 103 AHFLHGCNSKKAYFLYMYSRYLSGEKKKDDETVDSLGPLEKGQVKNEALRELRVELS--- 159 A+ L SKK+ +L Y + L K E L + + Sbjct: 564 AYALQVFPSKKSVWLRAA--YFEKNHGTRESLEALLQRAVAHCPKAEVLWLMGAKSKWLA 621 Query: 160 ----------KKHQARELDGFGLYLYGVVLRKLDLVKE-AIDVFVEATHVLP-------- 200 + ++L V L + E A + +A P Sbjct: 622 GDVPAARSILALAFQANPNSEEIWLAAVKLESENDEYERARRLLAKARSSAPTARVFMKS 681 Query: 201 --LHW-----GAWLELCNLITDKEMLKFLSLPDTWMKEFFLAHIYTELQLIEEALQKYQN 253 L W A +LC ++ + + P WM + E + + E ++ N Sbjct: 682 VKLEWVQDNIRAAQDLC----EEALRHYEDFPKLWM----MKGQIEEQKEMMEKAREAYN 733 Query: 254 LIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNLL-YVRSM 312 S+ + ++ I + +A +I + R ++P + + S L Y + Sbjct: 734 QGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNP-KNPGLWLESVRLEYRAGL 792 Query: 313 KSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMG 372 K+ + L + + + K+ ++ + +P L A + Sbjct: 793 KNIANTLMAKALQECPNSGILWSEAIFLEARPQRRTKSVDALKKC-EHDPHVLLAVAKL- 850 Query: 373 HEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPND 432 + + + A + + ++++ AW + +R P Sbjct: 851 --FWSQRKITKAREWFHRTVKIDSDLGDAWAFFYKFELQHGTEEQQEEVRKRCESAEPRH 908 Query: 433 SRMLVALGE 441 + A+ + Sbjct: 909 GELWCAVSK 917 >5XJC-J nrPDB Length = 848 Score = 50.9 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 26/162 (16%), Positives = 59/162 (36%), Gaps = 2/162 (1%) Query: 334 CCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIE 393 + + ++A ++RAL ++ R + W M+ + + A + AI Sbjct: 245 WIKYAQWEESLKEIQRARSIYERALDVDYRNITLWLKYAEMEMKNRQVNHARNIWDRAIT 304 Query: 394 VNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAK 453 R + WY E+L + R + +P + + + + ++ A+ Sbjct: 305 TLPRVNQFWYKYTYMEEMLGNVAGARQVFERWMEWQPEE-QAWHSYINFELRYKEVDRAR 363 Query: 454 KCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYIKYIQ 495 Y R V + +K A+ E+ A + Y + ++ Sbjct: 364 TIYERFVLVHP-DVKNWIKYARFEEKHAYFAHARKVYERAVE 404 Score = 31.3 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 35/193 (18%), Positives = 61/193 (31%), Gaps = 47/193 (24%) Query: 349 KAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNK-----RDYRAWY 403 K ++ +K NP AW A + Y AI R ++ + Sbjct: 475 KRRFQYEEEVKANPHNYDAWFDYLRLVESDAEAEAVREVYERAIANVPPIQEKRHWKRYI 534 Query: 404 GLGQTYEI-----LKMPFYCLYYYRRAHQLRPN----DSRMLV----------------- 437 L Y + K P Y+ + +L P+ ++M + Sbjct: 535 YLWINYALYEELEAKDPERTRQVYQASLELIPHKKFTFAKMWILYAQFEIRQKNLSLARR 594 Query: 438 ----ALGEC---------YEKLNQLVEAKKC---YWRAYAVGDVEKMALVKLAKLHEQLT 481 ++G+C E QL E +C Y + G + +K A+L L Sbjct: 595 ALGTSIGKCPKNKLFKVYIELELQLREFDRCRKLYEKFLEFGPENCTSWIKFAELETILG 654 Query: 482 ESEQAAQCYIKYI 494 + ++A Y I Sbjct: 655 DIDRARAIYELAI 667 >3JB9-R nrPDB Length = 674 Score = 49.8 bits (117), Expect = 3e-06, Method: Composition-based stats. Identities = 29/162 (17%), Positives = 61/162 (37%), Gaps = 2/162 (1%) Query: 334 CCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIE 393 G + + + +A F+RAL ++ Y+ W M+ +N + A + A+ Sbjct: 73 WMRYGQWELDQKEFARARSVFERALDVDSTYIPLWLKYIECEMKNRNINHARNLFDRAVT 132 Query: 394 VNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAK 453 R + WY E+L C + R + P+++ + + E+ E Sbjct: 133 QLPRVDKLWYKYVYMEEMLGNITGCRQVFERWLKWEPDENCWMSYIR--MERRYHENERA 190 Query: 454 KCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYIKYIQ 495 + + + V E ++ A+ E+ + Q Y+ I Sbjct: 191 RGIYERFVVVHPEVTNWLRWARFEEECGNAANVRQVYLAAID 232 Score = 34.4 bits (77), Expect = 0.15, Method: Composition-based stats. Identities = 20/122 (16%), Positives = 38/122 (31%), Gaps = 1/122 (0%) Query: 375 YMEMKNTSA-AIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDS 433 E++ + + AI N+ W GQ K + RA + Sbjct: 45 LEELQEFQGRKRKEFEDAIRRNRLAMGHWMRYGQWELDQKEFARARSVFERALDVDSTYI 104 Query: 434 RMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYIKY 493 + + EC K + A+ + RA K + E L Q + ++ Sbjct: 105 PLWLKYIECEMKNRNINHARNLFDRAVTQLPRVDKLWYKYVYMEEMLGNITGCRQVFERW 164 Query: 494 IQ 495 ++ Sbjct: 165 LK 166 >5WQL-B nrPDB Length = 278 Score = 49.8 bits (117), Expect = 4e-06, Method: Composition-based stats. Identities = 46/216 (21%), Positives = 76/216 (35%), Gaps = 11/216 (5%) Query: 327 DKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQ 386 D R + G Y A F +AL + P + +G + N AA + Sbjct: 42 DDERAQLLYERGVLYDSLGLRALARNDFSQALAIRPDMPEVFNYLGIYLTQAGNFDAAYE 101 Query: 387 AYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSR--MLVALGECYE 444 A+ +E++ A G +Q PND + + L E + Sbjct: 102 AFDSVLELDPTYNYAHLNRGIALYYGGRDKLAQDDLLAFYQDDPNDPFRSLWLYLAE--Q 159 Query: 445 KLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYIKYIQDIYSCGEIV 504 KL++ +AK+ + + D E+ + + SEQ +K D + Sbjct: 160 KLDE-KQAKEVLKQHFEKSDKEQWGWNIVEFYLGNI--SEQTLMERLKA--DATDNTSLA 214 Query: 505 EHLEESTAFRYLAQYYFKCKLWDEASTCAQKCCAFN 540 EHL E+ YL +YY D A+ + A N Sbjct: 215 EHLSETNF--YLGKYYLSLGDLDSATALFKLAVANN 248 >1A17-A nrPDB Length = 166 Score = 49.4 bits (116), Expect = 5e-06, Method: Composition-based stats. Identities = 33/143 (23%), Positives = 59/143 (41%), Gaps = 6/143 (4%) Query: 330 RVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYR 389 R E N Y +E A ++ +A++LNP + Y+ + A+ Sbjct: 12 RAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDAT 71 Query: 390 HAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQL 449 AIE++K+ + +Y + L L Y +++P+D + EC + + Q Sbjct: 72 RAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQ- 130 Query: 450 VEAKKCYWRAYAVGDVEKMALVK 472 K + RA A GD K ++V Sbjct: 131 ----KAFERAIA-GDEHKRSVVD 148 >2C2L-A nrPDB Length = 281 Score = 49.0 bits (115), Expect = 5e-06, Method: Composition-based stats. Identities = 31/146 (21%), Positives = 61/146 (41%), Gaps = 10/146 (6%) Query: 338 GNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKR 397 GN + ++ +AA + RA+ NP +T Y++M+ A+ R A+E++ + Sbjct: 11 GNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQPEQALADCRRALELDGQ 70 Query: 398 DYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYW 457 +A + LGQ ++ + +RA+ L G+ ++ AKK W Sbjct: 71 SVKAHFFLGQCQLEMESYDEAIANLQRAYSLAKEQRL---NFGDDIPSALRI--AKKKRW 125 Query: 458 RAYAVGDVEKMALVKLAKLHEQLTES 483 + + + + +LH LT Sbjct: 126 NSIEERRIHQES-----ELHSYLTRL 146 Score = 48.3 bits (113), Expect = 1e-05, Method: Composition-based stats. Identities = 21/104 (20%), Positives = 35/104 (33%) Query: 364 YLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYR 423 G+ + A Y AI N + Y ++ P L R Sbjct: 3 SAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQPEQALADCR 62 Query: 424 RAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEK 467 RA +L + LG+C ++ EA RAY++ ++ Sbjct: 63 RALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSLAKEQR 106 >5ZYQ-A nrPDB Length = 320 Score = 48.3 bits (113), Expect = 9e-06, Method: Composition-based stats. Identities = 23/128 (17%), Positives = 40/128 (31%), Gaps = 7/128 (5%) Query: 316 LSYLAHNLCEIDKYRVE--TCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGH 373 L +A + D+ + C + ++A F L +P + A Sbjct: 116 LYTMADKIIMYDQNHLLGRACF----CLLEGDKMDQADAQFHFVLNQSPNNIPALLGKAC 171 Query: 374 EYMEMKNTSAAIQAYRHAIEVNKRD-YRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPND 432 K+ A+ Y+ A+ N G+G + L + RA +L Sbjct: 172 ISFNKKDYRGALAYYKKALRTNPGCPAEVRLGMGHCFVKLNKLEKARLAFSRALELNSKC 231 Query: 433 SRMLVALG 440 LV L Sbjct: 232 VGALVGLA 239 Score = 35.9 bits (81), Expect = 0.052, Method: Composition-based stats. Identities = 27/145 (18%), Positives = 54/145 (37%), Gaps = 6/145 (4%) Query: 251 YQNLID-VGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYV 309 + D + ++++ + +D+A + F+ + Q P I + Sbjct: 116 LYTMADKIIMYDQNHLLGRACFCLLEGDKMDQADAQFHFVLNQSPNNIPAL--LGKACIS 173 Query: 310 RSMKS---ELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLG 366 + K L+Y L E +G+ + ++ EKA L F RAL+LN + +G Sbjct: 174 FNKKDYRGALAYYKKALRTNPGCPAEVRLGMGHCFVKLNKLEKARLAFSRALELNSKCVG 233 Query: 367 AWTLMGHEYMEMKNTSAAIQAYRHA 391 A + + K + Y + Sbjct: 234 ALVGLAVLELNNKEADGSENLYFQS 258 >6AF0-A nrPDB Length = 939 Score = 47.9 bits (112), Expect = 1e-05, Method: Composition-based stats. Identities = 53/291 (18%), Positives = 109/291 (37%), Gaps = 37/291 (12%) Query: 202 HWGAWLELCNLITDKEM-LKFLSLPDTWMKEFFLAHIYTELQLIEEALQKYQNLIDVGFS 260 + A L+ C I+ E L +L T ++ Y I++A++ Y+ L+ Sbjct: 553 FFQAALDSCARISQTENDLDIDALLTTIPFNLGRSYEY--EGDIDKAIETYEQLLSR--- 607 Query: 261 KSSYIVSQIAVAYHNIRDI--DKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKSELSY 318 S Y ++ +AY +R + +L +++P +E + L + K + Sbjct: 608 HSDYTDARTRLAYIKLRRNPNKEGPDAVAKLYQENPSDLEVRGLYGWFLSKVNSKKRPAN 667 Query: 319 LA---------HNLCEIDKYRVETCCVIGNYYSLRSQ----------------HEKAALY 353 +A H L DK+ +GN + + ++ + +A + Sbjct: 668 IAEDPEQRHYKHTLQSYDKHDRYALVGMGNLHLMAAREMRRETEQDRQKRSAAYNRAVEF 727 Query: 354 FQRALKLNPRYLGAWTLMGHEYME-MKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEIL 412 F +AL+L+P+ A + +E K+ A+Q + + +D + +G Y L Sbjct: 728 FDKALQLDPKNAYAAQGIAIALVEDRKDYKNALQIFIK-VRETIQDAHVYVNMGHIYAEL 786 Query: 413 KMPFYCLYYYRRAHQL--RPNDSRMLVALGECYEKLNQLVEAKKCYWRAYA 461 + + Y A + ND+ ++ LG + + Y A Sbjct: 787 RQFSKAIESYEIALSKEGKANDAGIISCLGRTWLNKGRAERNLDAYKMALD 837 Score = 34.8 bits (78), Expect = 0.10, Method: Composition-based stats. Identities = 24/124 (19%), Positives = 41/124 (33%), Gaps = 13/124 (10%) Query: 337 IGNYYSLRSQHEKAALYFQRAL----KLNPR----YLGAWT-----LMGHEYMEMKNTSA 383 IG +YS +H A +FQ AL +++ + A +G Y + Sbjct: 537 IGCFYSQEGKHRLATEFFQAALDSCARISQTENDLDIDALLTTIPFNLGRSYEYEGDIDK 596 Query: 384 AIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECY 443 AI+ Y + + A L + +Q P+D + G Sbjct: 597 AIETYEQLLSRHSDYTDARTRLAYIKLRRNPNKEGPDAVAKLYQENPSDLEVRGLYGWFL 656 Query: 444 EKLN 447 K+N Sbjct: 657 SKVN 660 Score = 34.0 bits (76), Expect = 0.21, Method: Composition-based stats. Identities = 37/241 (15%), Positives = 63/241 (26%), Gaps = 59/241 (24%) Query: 275 NIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDKY----- 329 + AL F E + R N+L V L L + Y Sbjct: 170 KAEQLRNALKSFEEAIRVSQGR--------NMLAVMGKARALFSLGRYPESLAAYQDVVA 221 Query: 330 ------RVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSA 383 + IG + + A + ++R L++NP A L+G Sbjct: 222 KMPDMVDPDPRIGIGCCFWQLGFKDDAKIAWERCLEINPDSKHANILLG----------- 270 Query: 384 AIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAH--------QLRPNDSRM 435 Y L + + + Y++A +L N Sbjct: 271 ------------------LYYLDASGHVPTNSPEFIRLYKKAMTEYTQKSFKLDKNLPLT 312 Query: 436 LVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMA---LVKLAKLHEQLTESEQAAQCYIK 492 + Q +A DV +A LA+ E+A+ Y + Sbjct: 313 CATFAGYFLSRKQFGNVDALAHKAIQYTDVNAIASDGWYLLARKEHYDGNLERASDYYRR 372 Query: 493 Y 493 Sbjct: 373 A 373 >4ZLH-A nrPDB Length = 339 Score = 47.5 bits (111), Expect = 2e-05, Method: Composition-based stats. Identities = 30/185 (16%), Positives = 66/185 (35%), Gaps = 6/185 (3%) Query: 249 QKYQNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLY 308 Q + + + + Q+ Y D+A +FN+L + +RI + + Sbjct: 43 QTLMESASLTYEQRLLAIQQLGRDYMAAGLYDRAEDMFNQLTDETDFRIGALQQLLQIYQ 102 Query: 309 VRSMKSELSYLAHNLCEI--DKYRVET---CCVIGNYYSLRSQHEKAALYFQRALKLNPR 363 S + +A L ++ DK RVE C + + ++A ++ + Sbjct: 103 ATSEWQKAIDVAERLVKLGKDKQRVEIAHFYCELALQHMASDDLDRAMTLLKKGAAADKN 162 Query: 364 YLGAWTLMGHEYMEMKNTSAAIQAYRHAI-EVNKRDYRAWYGLGQTYEILKMPFYCLYYY 422 +MG +M + A+++ + I + + L Y+ L + Sbjct: 163 SARVSIMMGRVFMAKGEYAKAVESLQRVISQDRELVSETLEMLQTCYQQLGKTAEWAEFL 222 Query: 423 RRAHQ 427 +RA + Sbjct: 223 QRAVE 227 Score = 31.3 bits (69), Expect = 1.4, Method: Composition-based stats. Identities = 23/128 (17%), Positives = 45/128 (35%), Gaps = 7/128 (5%) Query: 348 EKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQ 407 +KA F LK + + A +G+ + AI+ ++ + + + Sbjct: 2 DKAVDLFLDMLKEDTGTVEAHLTLGNLFRSRGEVDRAIRIHQT---LMESASLTYEQRLL 58 Query: 408 TYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEK 467 + L + Y RA + + ++L Q+ +A + +A V Sbjct: 59 AIQQLGRDYMAAGLYDRAEDMFNQLTDETDFRIGALQQLLQIYQATSEWQKAIDV----A 114 Query: 468 MALVKLAK 475 LVKL K Sbjct: 115 ERLVKLGK 122 Score = 29.8 bits (65), Expect = 3.4, Method: Composition-based stats. Identities = 37/242 (15%), Positives = 83/242 (34%), Gaps = 24/242 (9%) Query: 148 NEALRELRVELSKKHQARELDGFGLYLYGVVLRKLDLVKEAIDVFVEATHVLPLHWGAWL 207 + A+R + + E + G L A D+F + T GA Sbjct: 36 DRAIRIHQTLMESASLTYEQRLLAIQQLGRDYMAAGLYDRAEDMFNQLTDETDFRIGAL- 94 Query: 208 ELCNLITDKEMLKFLSLPDTWMKEFFLAHIYTELQLIEEALQKYQNLIDVGFSKSSYIVS 267 +++L+ W K I+ A + + D + ++ Sbjct: 95 --------QQLLQIYQATSEWQKA------------IDVAERLVKLGKDKQRVEIAHFYC 134 Query: 268 QIAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKSELSYLAHNLCEID 327 ++A+ + D+D+A+++ + D + + ++ + D Sbjct: 135 ELALQHMASDDLDRAMTLLKKGAAADKNSARVSIMMGRVFMAKGEYAKAVESLQRVISQD 194 Query: 328 KYRV-ETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQ 386 + V ET ++ Y + + A + QRA++ A ++ + +E ++ S A Q Sbjct: 195 RELVSETLEMLQTCYQQLGKTAEWAEFLQRAVE-ENTGADAELML-ADIIEARDGSEAAQ 252 Query: 387 AY 388 Y Sbjct: 253 VY 254 >4I9E-A nrPDB Length = 383 Score = 47.1 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 48/276 (17%), Positives = 100/276 (36%), Gaps = 40/276 (14%) Query: 272 AYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKS-ELSYLAHNLCEIDKYR 330 Y+++ + L + L + RIE S+LL K L+ L + Sbjct: 53 LYYSLMEFRHNLML-EYLEPLEKMRIEEQPRLSDLLLEIDKKQARLTGLLEYYFNFFR-- 109 Query: 331 VETCCVIGNYYSLRSQHEKAALYFQRAL--------KLNP-----RYLGAWTLMGHEYME 377 G Y + ++ A +F++A ++ + ++ M Y Sbjct: 110 -------GMYELDQREYLSAIKFFKKAESKLIFVKDRIEKAEFFFKMSESYYYMKQTYFS 162 Query: 378 MKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDS---- 433 M A + Y+ N R + + LK + ++++A+ + + Sbjct: 163 MDYARQAYEIYKEHEAYNIRLLQCHSLFATNFLDLKQYEDAISHFQKAYSMAEAEKQPQL 222 Query: 434 --RMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEK------MALVKLAKLHEQLTESEQ 485 R L +G C +Q +A + RA AV + A + ++H +L + ++ Sbjct: 223 MGRTLYNIGLCKNSQSQYEDAIPYFKRAIAVFEESNILPSLPQAYFLITQIHYKLGKIDK 282 Query: 486 AAQCYIKYIQDIYSCGEIVEHLEESTAFRYLAQYYF 521 A + + K + G+++ +L E F +L Y Sbjct: 283 AHEYHSKGMAYSQKAGDVI-YLSE---FEFLKSLYL 314 >5UDI-A nrPDB Length = 479 Score = 47.1 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 47/282 (16%), Positives = 102/282 (36%), Gaps = 29/282 (10%) Query: 216 KEMLKFLSLPDTWMKEFFLAHIYTELQLIEEALQKY---QNLIDVGFSKSSYIVSQI--- 269 + ++FL + LA++ EEAL+ +NL+ + + S + Sbjct: 41 LDQIEFLDTKYSVGIHNLLAYVKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWG 100 Query: 270 --AVAYHNIRDIDKALSIFNEL-----RKQDP--YRIENMDTFSNLLYVRSM-----KSE 315 A Y+++ + +A + +++ + +P YR+E + + Sbjct: 101 NFAWMYYHMGRLAEAQTYLDKVENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYER 160 Query: 316 LSYLAHNLCEIDKYRVE--TCCVIGNY----YSLRSQHEK--AALYFQRALKLNPRYLGA 367 + E+D E I Y + L +++ K + L ++A++LNP Sbjct: 161 AKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYI 220 Query: 368 WTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQ 427 L+ + + + + A+ + + Y L ++A Q Sbjct: 221 KVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQ 280 Query: 428 LRPNDSRMLVALGECYE-KLNQLVEAKKCYWRAYAVGDVEKM 468 P + +G CY+ ++ Q+ EA K R ++KM Sbjct: 281 ETPTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNREKLDKM 322 Score = 39.0 bits (89), Expect = 0.006, Method: Composition-based stats. Identities = 18/143 (12%), Positives = 39/143 (27%), Gaps = 22/143 (15%) Query: 318 YLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYM- 376 Y+ L + +Y + +KA ++AL+ P + +G Y Sbjct: 240 YIEEALANMSSQTYVFRYAA-KFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKA 298 Query: 377 ----------------EMKNTSA----AIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPF 416 + AI + A+E A L + Y Sbjct: 299 QMIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHR 358 Query: 417 YCLYYYRRAHQLRPNDSRMLVAL 439 +++ ++P + + Sbjct: 359 KAEENFQKLLCMKPVVEETMQDI 381 Score = 37.1 bits (84), Expect = 0.021, Method: Composition-based stats. Identities = 26/160 (16%), Positives = 52/160 (32%), Gaps = 13/160 (8%) Query: 345 SQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYG 404 + Y +++ A G KN A + +EV+ + + G Sbjct: 127 KKLSNPFRYRMECPEIDCEEGWALLKCGG-----KNYERAKACFEKVLEVDPENPESSAG 181 Query: 405 LGQTYEILKMPFYCLYYY--------RRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCY 456 + L + R+A +L P++ + V L + Q E +K Sbjct: 182 YAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYI 241 Query: 457 WRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYIKYIQD 496 A A + AK + + ++A + K +Q+ Sbjct: 242 EEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQE 281 >5JZ6-A nrPDB Length = 429 Score = 46.3 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 25/201 (12%), Positives = 54/201 (26%), Gaps = 18/201 (8%) Query: 307 LYVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLN----- 361 L R E L ++ ++ + A++ Sbjct: 22 LRKRGKIEEAVNAFKELVRKYPQSPRARYGKAQCEDDLAEKRRSNEVLRGAIETYQEVAS 81 Query: 362 ----PRYLGAWTLMGHEYME--MKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMP 415 P L +L + + + ++ + +++ D LG Y ++ Sbjct: 82 LPDVPADLLKLSLKRRSDRQQFLGHMRGSLLTLQRLVQLFPNDTSLKNDLGVGYLLIGDN 141 Query: 416 FYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGD---VEKMALVK 472 Y + PND V G + N++ E+ GD + Sbjct: 142 DNAKKVYEEVLSVTPNDGFAKVHYGFILKAQNKIAESIPYLKEGIESGDPGTDDGRFYFH 201 Query: 473 LAKLHEQLTESEQAAQCYIKY 493 L +++ + Y Y Sbjct: 202 LGDAMQRVGN----KEAYKWY 218 >4HOQ-A nrPDB Length = 482 Score = 44.4 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 26/152 (17%), Positives = 61/152 (40%), Gaps = 19/152 (12%) Query: 349 KAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEV----NKRDYRAWYG 404 A +F+ A++ + + A+T + + Y E S A +R A+ + + ++ Y Sbjct: 322 SAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENITDDHKHQIHYH 381 Query: 405 LG---QTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYA 461 G + + + +++Y A +++ + L +L + C+ Sbjct: 382 YGRFQEFHRKSENT--AIHHYLEALKVKDRSPLR----TKLTSALKKLSTKRLCH----- 430 Query: 462 VGDVEKMALVKLAKLHEQLTESEQAAQCYIKY 493 ++ +L L +++ E QAA+ Y K Sbjct: 431 -NALDVQSLSALGFVYKLEGEKRQAAEYYEKA 461 Score = 40.2 bits (92), Expect = 0.003, Method: Composition-based stats. Identities = 37/287 (12%), Positives = 86/287 (29%), Gaps = 50/287 (17%) Query: 158 LSKKHQARELDGFGLYLYGVVLRKLDLVKEAIDVFVEATHVLPL--HWGAWLELCNLITD 215 + + + L R+ + +A+++ +A V P + LC Sbjct: 238 IEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQM 297 Query: 216 KEMLKFLSLPDTWMKEFFLAHIYTELQLIEEALQKYQNLIDVGFSKSSYIVSQIAVAYHN 275 ++ K + + + + +A + ++ ++ + +A Y Sbjct: 298 IQIKKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMF-------AFAYTDLANMYAE 350 Query: 276 IRDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDKYRVETCC 335 A IF + + + D ++ + Sbjct: 351 GGQYSNAEDIFRKALRLENI------------------------------TDDHKHQIHY 380 Query: 336 VIGNYYSLRSQHEK-AALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEV 394 G + + E A ++ ALK+ R T + ++ + Sbjct: 381 HYGRFQEFHRKSENTAIHHYLEALKVKDRS-PLRTKLTSALKKLS---------TKRLCH 430 Query: 395 NKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGE 441 N D ++ LG Y++ YY +A ++ P ++ L AL E Sbjct: 431 NALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALCE 477 Score = 37.5 bits (85), Expect = 0.018, Method: Composition-based stats. Identities = 44/302 (14%), Positives = 91/302 (30%), Gaps = 41/302 (13%) Query: 190 DVFVEATHVLPLHWGAWLELCNLITDKEM-------LKFLSLPDTWMKEFFLAHIYTELQ 242 D L H+ W L I E+ L+FL+ LA++ Sbjct: 7 DTLKAILLELECHFT-WNLLKEDIDLFEVEDTIGQQLEFLTTKSRLALYNLLAYVKHLKG 65 Query: 243 LIEEALQKY--------QNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIF-------N 287 ++AL+ Q D +S A Y+++ +++A Sbjct: 66 QNKDALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKIGNVCK 125 Query: 288 ELRKQDPYRIENMDTFSNLLYVRSMKSELSYLA-----HNLCEIDKYRVETCCVIGNYYS 342 +L Y++E +T + Y E++ E IG + Sbjct: 126 KLSSPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPE--FNIGYAIT 183 Query: 343 LRSQHEKAALY---------FQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIE 393 + + ++A+ LNP + + ++ + + ++ Sbjct: 184 VYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILD 243 Query: 394 VNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAK 453 + Y L ++A ++ P S + +G CY Q+++ K Sbjct: 244 QISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYR--AQMIQIK 301 Query: 454 KC 455 K Sbjct: 302 KA 303 >1IHG-A nrPDB Length = 370 Score = 44.4 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 24/104 (23%), Positives = 48/104 (46%), Gaps = 1/104 (0%) Query: 359 KLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYC 418 KL P L +G ++M + A+ + A+E++ + +A Y Q ++ LK Sbjct: 267 KLQPVALSCVLNIGACKLKMSDWQGAVDSCLEALEIDPSNTKALYRRAQGWQGLKEYDQA 326 Query: 419 LYYYRRAHQLRPNDSRMLVALGECYEKL-NQLVEAKKCYWRAYA 461 L ++A ++ P D + L + +K+ Q + K Y + +A Sbjct: 327 LADLKKAQEIAPEDKAIQAELLKVKQKIKAQKDKEKAAYAKMFA 370 Score = 43.2 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 17/140 (12%), Positives = 50/140 (35%), Gaps = 17/140 (12%) Query: 370 LMGHEYMEMKNTSAAIQAYRHAIE----------------VNKRDYRAWYGLGQTYEILK 413 +G+ + + +N AI+ Y + + +G + Sbjct: 228 NIGNTFFKSQNWEMAIKKYTKVLRYVEGSRAAAEDADGAKLQPVALSCVLNIGACKLKMS 287 Query: 414 MPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKL 473 + A ++ P++++ L + ++ L + +A +A + +K +L Sbjct: 288 DWQGAVDSCLEALEIDPSNTKALYRRAQGWQGLKEYDQALADLKKAQEIAPEDKAIQAEL 347 Query: 474 AKLHEQL-TESEQAAQCYIK 492 K+ +++ + ++ Y K Sbjct: 348 LKVKQKIKAQKDKEKAAYAK 367 Score = 37.9 bits (86), Expect = 0.012, Method: Composition-based stats. Identities = 24/187 (12%), Positives = 53/187 (28%), Gaps = 21/187 (11%) Query: 236 HIYTELQLIEEALQKYQNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPY 295 E +D S + + I + ++ + A+ + ++ + Sbjct: 197 GSGDSHPDFPEDADVDLKDVDKILLISEDLKN-IGNTFFKSQNWEMAIKKYTKVLR---- 251 Query: 296 RIENMDTFSNLLYVRSMKSELSYLAHNLCEIDKYRVETCCV-IGNYYSLRSQHEKAALYF 354 +E S + L + +C + IG S + A Sbjct: 252 YVEG-----------SRAAAEDADGAKLQPV----ALSCVLNIGACKLKMSDWQGAVDSC 296 Query: 355 QRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKM 414 AL+++P A + +K A+ + A E+ D L + + +K Sbjct: 297 LEALEIDPSNTKALYRRAQGWQGLKEYDQALADLKKAQEIAPEDKAIQAELLKVKQKIKA 356 Query: 415 PFYCLYY 421 Sbjct: 357 QKDKEKA 363 Score = 30.1 bits (66), Expect = 2.8, Method: Composition-based stats. Identities = 18/109 (16%), Positives = 36/109 (33%), Gaps = 16/109 (14%) Query: 403 YGLGQTYEILKMPFYCLYYYRRAH----------------QLRPNDSRMLVALGECYEKL 446 +G T+ + + Y + +L+P ++ +G C K+ Sbjct: 227 KNIGNTFFKSQNWEMAIKKYTKVLRYVEGSRAAAEDADGAKLQPVALSCVLNIGACKLKM 286 Query: 447 NQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYIKYIQ 495 + A A + AL + A+ + L E +QA K + Sbjct: 287 SDWQGAVDSCLEALEIDPSNTKALYRRAQGWQGLKEYDQALADLKKAQE 335 >3JCM-G nrPDB Length = 899 Score = 43.6 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 22/160 (13%), Positives = 49/160 (30%), Gaps = 1/160 (0%) Query: 324 CEIDKYRVETCCVIGNYYSLRSQHEKAALY-FQRALKLNPRYLGAWTLMGHEYMEMKNTS 382 + + + ++ A R L NP + + + + N Sbjct: 695 TRLVPNCPLLWVSLSKIDEIDLKNPVRARSILDRGLLKNPDDVLFYIAKIQMEIRLGNLD 754 Query: 383 AAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGEC 442 A A++ + W + ++ ++ A + ND R+L+ +G Sbjct: 755 QAELLVTQALQKFPSNALLWVEQIKLFKHGNKSSLKKTIFQDALRRTQNDHRVLLEIGVS 814 Query: 443 YEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTE 482 + Q + K RA V L + + +L + Sbjct: 815 FYAEAQYETSLKWLERALKKCSRYGDTWVWLFRTYARLGK 854 Score = 30.5 bits (67), Expect = 2.1, Method: Composition-based stats. Identities = 36/236 (15%), Positives = 69/236 (29%), Gaps = 20/236 (8%) Query: 250 KYQNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYV 309 K +S +++ AY N++ A N RK P + S LL Sbjct: 356 KMLEKATQFIPQSMDLLT----AYTNLQSYHNAKMTLNSFRKILPQE-PEIWIISTLLEE 410 Query: 310 RSM-----KSELSYLAHNLCEIDKY----RVETCCVIGNYYSLRSQHEKAALYFQRAL-- 358 R+ +S L L E+ K + + A+ Sbjct: 411 RNNPDIPVDKLVSLLKEGLLELSKNGYKATLSAWLKRAEALNDAPNSNLTCQAIVYAILE 470 Query: 359 --KLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPF 416 + + Y + +M ++ I + I+ + D W L E Sbjct: 471 WLRESGEYESELNNVDQILEKMPHSKVQIAVLKKLIQWDPCDTVLWSRLKMATESYHKIE 530 Query: 417 YCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVK 472 L +++ N + + E + L+ YW+A + + L+ Sbjct: 531 ELLAFFQELLFQTKNSDDIRANMRE--KSPGLLMMYVSEYWKAQKGDTRQTLVLID 584 Score = 30.1 bits (66), Expect = 2.4, Method: Composition-based stats. Identities = 24/193 (12%), Positives = 54/193 (27%), Gaps = 18/193 (9%) Query: 309 VRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAW 368 + + + L +++ RV + + + +++A +P W Sbjct: 190 QVNKPNAATDALSYLKDLENDRVNS--LSDATLEDLQKMRTILKSYRKA---DPTNPQGW 244 Query: 369 TLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQL 428 + + S A + + + R W + +E YC A Sbjct: 245 IASARLEEKARKFSVAKKIIENGCQECPRSSDIWLENIRLHE--SDVHYCKTLVATAINF 302 Query: 429 RPNDSRML----------VALGECYEKLNQLVEAKKCYWR-AYAVGDVEKMALVKLAKLH 477 P + V K Q + + W+ A + + + L K Sbjct: 303 NPTSPLLWFKAIDLESTTVNKYRVVRKALQEIPRDEGLWKLAVSFEADKAQVIKMLEKAT 362 Query: 478 EQLTESEQAAQCY 490 + + +S Y Sbjct: 363 QFIPQSMDLLTAY 375 >2Y4T-A nrPDB Length = 450 Score = 43.6 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 41/249 (16%), Positives = 88/249 (35%), Gaps = 18/249 (7%) Query: 320 AHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMK 379 NL VE +G Q A F A+ +P A+ ++ M Sbjct: 15 TENLYFQSMADVEKHLELGKKLLAAGQLADALSQFHAAVDGDPDNYIAYYRRATVFLAMG 74 Query: 380 NTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVAL 439 + AA+ I++ A G +++ + P+++ Sbjct: 75 KSKAALPDLTKVIQLKMDFTAARLQRGHLLLKQGKLDEAEDDFKKVLKSNPSENEE-KEA 133 Query: 440 GECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHE------QLTESEQAAQCYI-- 491 K +++ + A+ GD A+ L K+ E +L E A+C+I Sbjct: 134 QSQLIKSDEMQRLRSQALNAFGSGDYTA-AIAFLDKILEVCVWDAELRELR--AECFIKE 190 Query: 492 ----KYIQDIYSCGEIVEHLEESTAFRYLAQYYFKCKLWDEASTCAQKCCAFNDTREEGK 547 K I D+ + ++ + + AF ++ Y++ + + + ++C + + Sbjct: 191 GEPRKAISDLKAASKLKN--DNTEAFYKISTLYYQLGDHELSLSEVRECLKLDQDHKRCF 248 Query: 548 ALLRQILQL 556 A +Q+ +L Sbjct: 249 AHYKQVKKL 257 Score = 43.2 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 25/193 (12%), Positives = 61/193 (31%), Gaps = 15/193 (7%) Query: 307 LYVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLG 366 L ++ H + D + + + A + ++L + Sbjct: 36 LLAAGQLADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKVIQLKMDFTA 95 Query: 367 AWTLMGHEYMEMKNTSAAIQAYRHAIEVNKR---DYRAWYGLGQTYEIL----------- 412 A GH ++ A ++ ++ N + A L ++ E+ Sbjct: 96 ARLQRGHLLLKQGKLDEAEDDFKKVLKSNPSENEEKEAQSQLIKSDEMQRLRSQALNAFG 155 Query: 413 -KMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALV 471 + + + ++ D+ + EC+ K + +A A + + A Sbjct: 156 SGDYTAAIAFLDKILEVCVWDAELRELRAECFIKEGEPRKAISDLKAASKLKNDNTEAFY 215 Query: 472 KLAKLHEQLTESE 484 K++ L+ QL + E Sbjct: 216 KISTLYYQLGDHE 228 Score = 41.7 bits (96), Expect = 8e-04, Method: Composition-based stats. Identities = 30/183 (16%), Positives = 61/183 (33%), Gaps = 16/183 (8%) Query: 255 IDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNL-------- 306 + ++ +I+ Y+ + D + +LS E K D + + Sbjct: 203 ASKLKNDNTEAFYKISTLYYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIE 262 Query: 307 ----LYVRSMKSELSYLAHNLCEIDKYRVETCCVIG----NYYSLRSQHEKAALYFQRAL 358 L ++ + ++ + + E + +S + +A L Sbjct: 263 SAEELIRDGRYTDATSKYESVMKTEPSIAEYTVRSKERICHCFSKDEKPVEAIRVCSEVL 322 Query: 359 KLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYC 418 ++ P + A Y+ + AIQ Y A E N+ D + GL + +LK Sbjct: 323 QMEPDNVNALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQQIREGLEKAQRLLKQSQKR 382 Query: 419 LYY 421 YY Sbjct: 383 DYY 385 >4UZY-A nrPDB Length = 651 Score = 42.1 bits (97), Expect = 7e-04, Method: Composition-based stats. Identities = 28/200 (14%), Positives = 59/200 (29%), Gaps = 21/200 (10%) Query: 235 AHIYTELQLIEEALQKYQNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDP 294 + + Q EA+Q Q + +S +S + Y+ D A ++ +L P Sbjct: 24 IYTLIKEQKFAEAIQHLQYQLQ-NVPESRAALSLLGYCYYYTGQYDMASQMYEQLVTLYP 82 Query: 295 -------YRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQH 347 Y +++ + +Y + K+ + H + T ++ Y + Sbjct: 83 SNEDYKLYYAQSL--YKGGMYPEASKAVVKVEGH-------QKAVTTLLVACSYE-QDDL 132 Query: 348 EKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQ 407 + P G + AA Q + A++ Y + Sbjct: 133 TGCRRQLDKC---APEDPDTMVNTGCIMFKEGKFEAARQKFNDAVQALGYQPELLYNIAL 189 Query: 408 TYEILKMPFYCLYYYRRAHQ 427 Y K L + + Sbjct: 190 CYYKTKQFGPALKHLAEIIE 209 Score = 38.2 bits (87), Expect = 0.010, Method: Composition-based stats. Identities = 28/189 (14%), Positives = 52/189 (27%), Gaps = 53/189 (28%) Query: 343 LRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAW 402 + +A + Q L+ P A +L+G+ Y A Q Y + + + Sbjct: 29 KEQKFAEAIQHLQYQLQNVPESRAALSLLGYCYYYTGQYDMASQMYEQLVTLYPSNEDYK 88 Query: 403 YGLGQTYEILKMPFYCLYY------YRRAH----------------------QLRPNDSR 434 Q+ M +++A + P D Sbjct: 89 LYYAQSLYKGGMYPEASKAVVKVEGHQKAVTTLLVACSYEQDDLTGCRRQLDKCAPEDPD 148 Query: 435 MLVALGECYEKLNQLVEAKK---------------------CYWRAYAVGDVEKMALVKL 473 +V G K + A++ CY++ G AL L Sbjct: 149 TMVNTGCIMFKEGKFEAARQKFNDAVQALGYQPELLYNIALCYYKTKQFGP----ALKHL 204 Query: 474 AKLHEQLTE 482 A++ E+ Sbjct: 205 AEIIEKAVR 213 Score = 37.1 bits (84), Expect = 0.021, Method: Composition-based stats. Identities = 17/94 (18%), Positives = 32/94 (34%) Query: 362 PRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYY 421 P G +T + ++ + + AIQ ++ ++ A LG Y Sbjct: 14 PIAEGQYTQTIYTLIKEQKFAEAIQHLQYQLQNVPESRAALSLLGYCYYYTGQYDMASQM 73 Query: 422 YRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKC 455 Y + L P++ + + K EA K Sbjct: 74 YEQLVTLYPSNEDYKLYYAQSLYKGGMYPEASKA 107 Score = 32.5 bits (72), Expect = 0.59, Method: Composition-based stats. Identities = 13/82 (15%), Positives = 28/82 (34%) Query: 411 ILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMAL 470 + + + + Q P L LG CY Q A + Y + + + Sbjct: 29 KEQKFAEAIQHLQYQLQNVPESRAALSLLGYCYYYTGQYDMASQMYEQLVTLYPSNEDYK 88 Query: 471 VKLAKLHEQLTESEQAAQCYIK 492 + A+ + +A++ +K Sbjct: 89 LYYAQSLYKGGMYPEASKAVVK 110 >5OMP-A nrPDB Length = 462 Score = 40.9 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 25/168 (14%), Positives = 52/168 (30%), Gaps = 19/168 (11%) Query: 246 EALQKYQNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSN 305 E ++ + + + IV + Y +A+ + ++ + ++ Sbjct: 256 EKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKI-------VSWLEMEYG 308 Query: 306 LLYVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYL 365 L S SE LA + Y ++ KA +AL L+ Sbjct: 309 LSEKESKASESFLLA------------AFLNLAMCYLKLREYTKAVECCDKALGLDSANE 356 Query: 366 GAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILK 413 G + M +A + +EVN ++ A + + K Sbjct: 357 KGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAK 404 Score = 33.2 bits (74), Expect = 0.36, Method: Composition-based stats. Identities = 28/163 (17%), Positives = 60/163 (36%), Gaps = 24/163 (14%) Query: 338 GNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKR 397 G Y ++ +A + + + + +W M EY + S A +++ A Sbjct: 280 GTVYFKGGKYMQAVIQYGKIV--------SWLEM--EYGLSEKESKASESFLLA------ 323 Query: 398 DYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYW 457 A+ L Y L+ + +A L + + L GE +N+ AK + Sbjct: 324 ---AFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFE 380 Query: 458 RAYAVGDVEKMALVKLAKLHEQLTESEQA-----AQCYIKYIQ 495 + V K A ++++ ++ E + A + K+ + Sbjct: 381 KVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAE 423 Score = 30.1 bits (66), Expect = 2.5, Method: Composition-based stats. Identities = 32/165 (19%), Positives = 58/165 (35%), Gaps = 23/165 (13%) Query: 390 HAIEVNKRDYRAWYGLGQTYE--ILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLN 447 A+E +R+ + LG Y P + + PN + + +EK Sbjct: 209 KALEKMQREEQCILYLGPRYGFGEAGKPKFG---------IEPNAELIYEVTLKSFEK-- 257 Query: 448 QLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYIK---YIQDIYSCGEIV 504 AK+ + + + + ++ + + QA Y K +++ Y E Sbjct: 258 ----AKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKE 313 Query: 505 EHLEES---TAFRYLAQYYFKCKLWDEASTCAQKCCAFNDTREEG 546 ES AF LA Y K + + +A C K + E+G Sbjct: 314 SKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKG 358 >4JHR-A nrPDB Length = 333 Score = 39.4 bits (90), Expect = 0.005, Method: Composition-based stats. Identities = 19/112 (16%), Positives = 43/112 (38%), Gaps = 14/112 (12%) Query: 337 IGNYYSLRSQHEKAALYFQR----ALKLNPRYLGAWTLM--GHEYMEMKNTSAAIQAYRH 390 +GN Y + E A+ Y+++ A +L R + A + G+ Y +++ AI + Sbjct: 157 LGNAYIFLGEFETASEYYKKTLLLARQLKDRAVEAQSCYSLGNTYTLLQDYEKAIDYHLK 216 Query: 391 AIEVNKRDYR-------AWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRM 435 + + + W LG Y L +++ + ++ + Sbjct: 217 HLAIAQELKDRIGEGRACWS-LGNAYTALGNHDQAMHFAEKHLEISREVGDL 267 Score = 39.0 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 29/157 (18%), Positives = 52/157 (33%), Gaps = 18/157 (11%) Query: 365 LGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYR------AWYGLGQTYEILKMPFYC 418 A+ +G+ + + N A+ A+ + + K A+ LG Y L Sbjct: 111 GRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETA 170 Query: 419 LYYYRRAHQLRPNDSRMLVA------LGECYEKLNQLVEAKKCYWRAYAVGDV------E 466 YY++ L V LG Y L +A + + A+ E Sbjct: 171 SEYYKKTLLLARQLKDRAVEAQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQELKDRIGE 230 Query: 467 KMALVKLAKLHEQLTESEQAAQCYIKYIQDIYSCGEI 503 A L + L +QA K+++ G++ Sbjct: 231 GRACWSLGNAYTALGNHDQAMHFAEKHLEISREVGDL 267 Score = 37.5 bits (85), Expect = 0.015, Method: Composition-based stats. Identities = 31/168 (18%), Positives = 52/168 (30%), Gaps = 38/168 (22%) Query: 365 LGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNK------RDYRAWYGLGQTY--------- 409 A +G+ + N AI + +++++ + RA Y LG Y Sbjct: 11 AKASGNLGNTLKVLGNFDEAIVCCQRHLDISRELNDKVGEARALYNLGNVYHAKGKSFGC 70 Query: 410 ---EILKMPFY--------CLYYYRRAHQL------RPNDSRMLVALGECYEKLNQLVEA 452 + + Y L R R LG + L +A Sbjct: 71 PGPQDTGEFPEDVRNALQAAVDLYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDA 130 Query: 453 KKCYWR----AYAVGD--VEKMALVKLAKLHEQLTESEQAAQCYIKYI 494 + + A GD E+ A L + L E E A++ Y K + Sbjct: 131 VIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTL 178 >1KT1-A nrPDB Length = 457 Score = 38.6 bits (88), Expect = 0.008, Method: Composition-based stats. Identities = 25/168 (14%), Positives = 52/168 (30%), Gaps = 19/168 (11%) Query: 246 EALQKYQNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSN 305 E ++ + + + IV + Y +A+ + ++ + ++ Sbjct: 251 EKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYVQAVIQYGKI-------VSWLEMEYG 303 Query: 306 LLYVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYL 365 L S SE LA + Y ++ KA +AL L+ Sbjct: 304 LSEKESKASESFLLA------------AFLNLAMCYLKLREYTKAVECCDKALGLDSANE 351 Query: 366 GAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILK 413 G + M +A + +EVN ++ A + + K Sbjct: 352 KGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQIFMCQKKAK 399 Score = 32.1 bits (71), Expect = 0.71, Method: Composition-based stats. Identities = 28/163 (17%), Positives = 59/163 (36%), Gaps = 24/163 (14%) Query: 338 GNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKR 397 G Y ++ +A + + + + +W M EY + S A +++ A Sbjct: 275 GTVYFKGGKYVQAVIQYGKIV--------SWLEM--EYGLSEKESKASESFLLA------ 318 Query: 398 DYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYW 457 A+ L Y L+ + +A L + + L GE +N+ AK + Sbjct: 319 ---AFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFE 375 Query: 458 RAYAVGDVEKMALVKLAKLHEQLTESEQA-----AQCYIKYIQ 495 + V K A +++ ++ E + A + K+ + Sbjct: 376 KVLEVNPQNKAARLQIFMCQKKAKEHNERDRRTYANMFKKFAE 418 Score = 29.0 bits (63), Expect = 5.5, Method: Composition-based stats. Identities = 32/165 (19%), Positives = 58/165 (35%), Gaps = 23/165 (13%) Query: 390 HAIEVNKRDYRAWYGLGQTYE--ILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLN 447 A+E +R+ + LG Y P + + PN + + +EK Sbjct: 204 KALEKMQREEQCILHLGPRYGFGEAGKPKFG---------IEPNAELIYEVTLKSFEK-- 252 Query: 448 QLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYIK---YIQDIYSCGEIV 504 AK+ + + + + ++ + + QA Y K +++ Y E Sbjct: 253 ----AKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYVQAVIQYGKIVSWLEMEYGLSEKE 308 Query: 505 EHLEES---TAFRYLAQYYFKCKLWDEASTCAQKCCAFNDTREEG 546 ES AF LA Y K + + +A C K + E+G Sbjct: 309 SKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKG 353 >1QZ2-A nrPDB Length = 336 Score = 38.6 bits (88), Expect = 0.008, Method: Composition-based stats. Identities = 23/145 (15%), Positives = 53/145 (36%), Gaps = 19/145 (13%) Query: 338 GNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKR 397 G Y ++++A L +++ + +W + + + QA R A Sbjct: 154 GTVYFKEGKYKQALLQYKKIV--------SWLEYESSFSNEE--AQKAQALRLA------ 197 Query: 398 DYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYW 457 + L + L+ + +A +L N+ + L GE + +N A+ + Sbjct: 198 ---SHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFELARADFQ 254 Query: 458 RAYAVGDVEKMALVKLAKLHEQLTE 482 + + K A +LA +++ Sbjct: 255 KVLQLYPNNKAAKTQLAVCQQRIRR 279 >5OJF-A nrPDB Length = 314 Score = 38.6 bits (88), Expect = 0.009, Method: Composition-based stats. Identities = 18/138 (13%), Positives = 43/138 (31%), Gaps = 16/138 (11%) Query: 238 YTELQLIEEALQKYQNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQ----- 292 L+ +AL + + + ++ +AV Y +A + + Sbjct: 87 KDAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVL 146 Query: 293 ---DPYRIENMDTFSNLLYVRSMKSELSYLAHNLCEI--------DKYRVETCCVIGNYY 341 P + + + L + E+ Y EI D +T + + Y Sbjct: 147 GKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCY 206 Query: 342 SLRSQHEKAALYFQRALK 359 + +++ A ++ L Sbjct: 207 LKQGKYQDAETLYKEILT 224 Score = 37.9 bits (86), Expect = 0.013, Method: Composition-based stats. Identities = 29/169 (17%), Positives = 51/169 (30%), Gaps = 24/169 (14%) Query: 313 KSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKL--------NPRY 364 K L L ++ Y +++++ AA AL + +P Sbjct: 52 KQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAAHLLNDALAIREKTLGKDHPAV 111 Query: 365 LGAWTLMGHEYMEMKNTSAAIQAYRHAIEVN--------KRDYRAWYGLGQTYEILKMPF 416 + Y + A + A+E+ + L + Sbjct: 112 AATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAE 171 Query: 417 YCLYYYRRAHQ-----LRPNDSRMLV---ALGECYEKLNQLVEAKKCYW 457 YYYRRA + L P+D + L CY K + +A+ Y Sbjct: 172 EVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYK 220 >3ZFW-A nrPDB Length = 263 Score = 37.5 bits (85), Expect = 0.016, Method: Composition-based stats. Identities = 18/138 (13%), Positives = 43/138 (31%), Gaps = 16/138 (11%) Query: 238 YTELQLIEEALQKYQNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQ----- 292 L+ +AL + + + ++ +AV Y +A + + Sbjct: 40 KDAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVL 99 Query: 293 ---DPYRIENMDTFSNLLYVRSMKSELSYLAHNLCEI--------DKYRVETCCVIGNYY 341 P + + + L + E+ Y EI D +T + + Y Sbjct: 100 GKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCY 159 Query: 342 SLRSQHEKAALYFQRALK 359 + +++ A ++ L Sbjct: 160 LKQGKYQDAETLYKEILT 177 Score = 36.7 bits (83), Expect = 0.028, Method: Composition-based stats. Identities = 29/169 (17%), Positives = 51/169 (30%), Gaps = 24/169 (14%) Query: 313 KSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKL--------NPRY 364 K L L ++ Y +++++ AA AL + +P Sbjct: 5 KQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAAHLLNDALAIREKTLGKDHPAV 64 Query: 365 LGAWTLMGHEYMEMKNTSAAIQAYRHAIEVN--------KRDYRAWYGLGQTYEILKMPF 416 + Y + A + A+E+ + L + Sbjct: 65 AATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAE 124 Query: 417 YCLYYYRRAHQ-----LRPNDSRMLV---ALGECYEKLNQLVEAKKCYW 457 YYYRRA + L P+D + L CY K + +A+ Y Sbjct: 125 EVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYK 173 >4ABN-A nrPDB Length = 474 Score = 37.5 bits (85), Expect = 0.018, Method: Composition-based stats. Identities = 16/66 (24%), Positives = 24/66 (36%), Gaps = 1/66 (1%) Query: 415 PFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLA 474 +A +L P LGE Y K + A C+ A K++L L+ Sbjct: 119 SPEAEVLLSKAVKLEPELVEAWNQLGEVYWKKGDVTSAHTCFSGALTHCK-NKVSLQNLS 177 Query: 475 KLHEQL 480 + QL Sbjct: 178 MVLRQL 183 Score = 35.9 bits (81), Expect = 0.049, Method: Composition-based stats. Identities = 29/160 (18%), Positives = 53/160 (33%), Gaps = 14/160 (8%) Query: 349 KAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQT 408 +A + +A+KL P + AW +G Y + + ++A + A+ K L Sbjct: 121 EAEVLLSKAVKLEPELVEAWNQLGEVYWKKGDVTSAHTCFSGALTHCKNKVS-LQNLSMV 179 Query: 409 Y---------EILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKL----NQLVEAKKC 455 E + + + A Q+ D R LG Y L Q + + Sbjct: 180 LRQLQTDSGDEHSRHVMDSVRQAKLAVQMDVLDGRSWYILGNAYLSLYFNTGQNPKISQQ 239 Query: 456 YWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYIKYIQ 495 AYA + LH + + Y + ++ Sbjct: 240 ALSAYAQAEKVDRKASSNPDLHLNRATLHKYEESYGEALE 279 Score = 30.9 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 31/214 (14%), Positives = 61/214 (28%), Gaps = 12/214 (5%) Query: 208 ELCNLITDKEMLKFLSLPDTWMKEFFLAHIYTELQLIEEALQKYQNLIDVGFSKSSYIVS 267 +L + + + L + ++ +F ++ + +D S + + Sbjct: 203 KLAVQMDVLDGRSWYILGNAYLSLYFNTGQNPKISQQALSAYAQAEKVDRKASSNPDLHL 262 Query: 268 QIAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKSEL---------SY 318 A + +AL F++ DP E LL S + L Sbjct: 263 NRATLHKYEESYGEALEGFSQAAALDPAWPEPQQREQQLLEFLSRLTSLLESKGKTKPKK 322 Query: 319 LAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEM 378 L L + + C G Y S Q K L + L P ++G + Sbjct: 323 LQSMLGSLRPAHLGP-CGDGRYQSASGQ--KMTLELKPLSTLQPGVNSGTVVLGKVVFSL 379 Query: 379 KNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEIL 412 + Y + Q++ +L Sbjct: 380 TTEEKVPFTFGLVDSDGPCYAVMVYNVVQSWGVL 413 >5OJ8-A nrPDB Length = 255 Score = 37.1 bits (84), Expect = 0.021, Method: Composition-based stats. Identities = 18/138 (13%), Positives = 44/138 (31%), Gaps = 16/138 (11%) Query: 238 YTELQLIEEALQKYQNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQ----- 292 L+ +AL + + + ++ +AV Y +A + + Sbjct: 109 KDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVL 168 Query: 293 ---DPYRIENMDTFSNLLYVRSMKSELSYLAHNLCEI--------DKYRVETCCVIGNYY 341 P + ++ + L + E+ Y EI D +T + + Y Sbjct: 169 GKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCY 228 Query: 342 SLRSQHEKAALYFQRALK 359 + + ++A ++ L Sbjct: 229 LKQGKFKQAETLYKEILT 246 Score = 33.2 bits (74), Expect = 0.30, Method: Composition-based stats. Identities = 17/115 (14%), Positives = 33/115 (28%), Gaps = 16/115 (13%) Query: 396 KRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLR--------PNDSRMLVALGECYEKLN 447 L Y +RA ++R P+ ++ L L + Sbjct: 131 PAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQG 190 Query: 448 QLVEAKKCYWRAYAV--------GDVEKMALVKLAKLHEQLTESEQAAQCYIKYI 494 + E + Y RA + LA + + + +QA Y + + Sbjct: 191 KYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEIL 245 >5IC8-A nrPDB Length = 334 Score = 37.1 bits (84), Expect = 0.022, Method: Composition-based stats. Identities = 13/81 (16%), Positives = 25/81 (30%) Query: 328 KYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQA 387 +E + + ++ RAL+L+P WTL G + + A Sbjct: 24 PGSIELWLAYLEFAAQVKATKRWRRIMTRALRLHPMNASLWTLAGRRAAQNGDMQRARAH 83 Query: 388 YRHAIEVNKRDYRAWYGLGQT 408 + R+ W + Sbjct: 84 FLRGCRFCTREPTLWLEYARC 104 >3NF1-A nrPDB Length = 311 Score = 36.7 bits (83), Expect = 0.026, Method: Composition-based stats. Identities = 18/138 (13%), Positives = 44/138 (31%), Gaps = 16/138 (11%) Query: 238 YTELQLIEEALQKYQNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQ----- 292 L+ +AL + + + ++ +AV Y +A + + Sbjct: 86 KDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVL 145 Query: 293 ---DPYRIENMDTFSNLLYVRSMKSELSYLAHNLCEI--------DKYRVETCCVIGNYY 341 P + ++ + L + E+ Y EI D +T + + Y Sbjct: 146 GKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCY 205 Query: 342 SLRSQHEKAALYFQRALK 359 + + ++A ++ L Sbjct: 206 LKQGKFKQAETLYKEILT 223 Score = 33.2 bits (74), Expect = 0.37, Method: Composition-based stats. Identities = 17/115 (14%), Positives = 33/115 (28%), Gaps = 16/115 (13%) Query: 396 KRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLR--------PNDSRMLVALGECYEKLN 447 L Y +RA ++R P+ ++ L L + Sbjct: 108 PAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQG 167 Query: 448 QLVEAKKCYWRAYAV--------GDVEKMALVKLAKLHEQLTESEQAAQCYIKYI 494 + E + Y RA + LA + + + +QA Y + + Sbjct: 168 KYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEIL 222 >5OQL-E nrPDB Length = 414 Score = 36.7 bits (83), Expect = 0.029, Method: Composition-based stats. Identities = 13/81 (16%), Positives = 25/81 (30%) Query: 328 KYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQA 387 +E + + ++ RAL+L+P WTL G + + A Sbjct: 104 PGSIELWLAYLEFAAQVKATKRWRRIMTRALRLHPMNASLWTLAGRRAAQNGDMQRARAH 163 Query: 388 YRHAIEVNKRDYRAWYGLGQT 408 + R+ W + Sbjct: 164 FLRGCRFCTREPTLWLEYARC 184 >5O09-1C nrPDB Length = 238 Score = 35.9 bits (81), Expect = 0.050, Method: Composition-based stats. Identities = 42/224 (18%), Positives = 76/224 (33%), Gaps = 41/224 (18%) Query: 277 RDIDKALSIFNELRKQ---DPYRIENMDTFSNLLYVRSMKSELSYLAHNLC--------E 325 R I A E R+ DP R+ + ++L K A +L E Sbjct: 6 RQIASASRSVEEARRLAYHDPIRVGALVEQISVLADLRQKEGDFRKAESLYREALFRAQE 65 Query: 326 IDKYRVE----TCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWT--------LMGH 373 + K + ++ + Y + +KAA +++ ALK++ + + Sbjct: 66 LRKQDPDLLTGIYSLLAHLYDRWGRMDKAAEFYELALKISAENGLEESDKVATIKNNLAM 125 Query: 374 EYMEMKNTSAAIQAYRHAIEV--------NKRDYRAWYGLGQTYEILKMPFYCLYYYRRA 425 + +++ A Y A+E + R + LG Y + RA Sbjct: 126 IFKQLRKFERAEGYYCEALETFQRLDGEQSARVASVYNNLGVLYYSHMDVDRAQVMHERA 185 Query: 426 H---------QLRPND-SRMLVALGECYEKLNQLVEAKKCYWRA 459 Q+ P D S+ + LG Y+ +A+ C RA Sbjct: 186 LAIRQNLHEGQMDPADLSQTFINLGAVYKAAGDFQKAEACVDRA 229 >4HOU-A nrPDB Length = 273 Score = 35.9 bits (81), Expect = 0.051, Method: Composition-based stats. Identities = 26/159 (16%), Positives = 51/159 (32%), Gaps = 13/159 (8%) Query: 345 SQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYG 404 + Y +++ A G KN A + +EV+ + + G Sbjct: 120 KKLSNPFRYRMECPEIDCEEGWALLKCGG-----KNYERAKACFEKVLEVDPENPESSAG 174 Query: 405 LGQTYEILKMPFYCLYYY--------RRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCY 456 + L + R+A +L P++ + V L + Q E +K Sbjct: 175 YAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYI 234 Query: 457 WRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYIKYIQ 495 A A + AK + + ++A + K +Q Sbjct: 235 EEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQ 273 Score = 32.5 bits (72), Expect = 0.49, Method: Composition-based stats. Identities = 25/179 (13%), Positives = 58/179 (32%), Gaps = 20/179 (11%) Query: 303 FSNLLYVRSMKSE-------LSYLAHNLCEIDKYR---VETCCVIGNYYSLRS-QHEKAA 351 F+ + Y +E + + L +YR E C G ++ + A Sbjct: 95 FAWMYYHMGRLAEAQTYLDKVENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERA 154 Query: 352 LY-FQRALKLNPRY--------LGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAW 402 F++ L+++P + A+ L G + + ++ R A+ +N + Sbjct: 155 KACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIK 214 Query: 403 YGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYA 461 L + Y A + + + + Y + + +A + +A Sbjct: 215 VLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQ 273 >5ZYP-A nrPDB Length = 390 Score = 35.2 bits (79), Expect = 0.096, Method: Composition-based stats. Identities = 41/254 (16%), Positives = 90/254 (35%), Gaps = 37/254 (14%) Query: 213 ITDKEMLKFLSLPDTWMKE-FFLAHIYTELQLIEEALQKYQNLIDVGFSKSSYIVSQIAV 271 + +++ + D +K L I E L ++ L++ K ++ IA+ Sbjct: 7 VEGYPSMEWPTSLDIPLKASEELVGIDLETDLPDDPTDLKTLLVEENSEKEHWL--TIAL 64 Query: 272 AYHNIRDIDKALSIFNELRKQ-DPYRIENMDTF----------SNLLYVRSMKSELSYLA 320 AY N ++ + + ++ TF L V + + EL+ Sbjct: 65 AYCNHGKTNEGIKLIEMALDVFQNSERASLHTFLTWAHLNLAKGQSLSVETKEHELTQAE 124 Query: 321 HNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGH------- 373 NL + + T IGN + + ++ +AL+ + ++ + H Sbjct: 125 LNLKDAIGFDP-TW--IGNMLATV-ELYYQRGHYDKALETSDLFVKSIHAEDHRSGRQSK 180 Query: 374 -----------EYMEMKNTSAAIQAYRHAIEVNKRDY-RAWYGLGQTYEILKMPFYCLYY 421 + KN A+++ ++ + +N G+G + LK + Sbjct: 181 PNCLFLLLRAKLLYQKKNYMASLKIFQELLVINPVLQPDPRIGIGLCFWQLKDSKMAIKS 240 Query: 422 YRRAHQLRPNDSRM 435 ++RA QL P ++ Sbjct: 241 WQRALQLNPKNTSA 254 Score = 30.5 bits (67), Expect = 1.9, Method: Composition-based stats. Identities = 33/166 (19%), Positives = 59/166 (35%), Gaps = 19/166 (11%) Query: 246 EALQKYQNLIDVGFSKSSYIVSQIAV--AYHNIRDIDKALS---IFNELRKQDPYRI--- 297 E Q NL D ++I + +A Y+ DKAL +F + + +R Sbjct: 119 ELTQAELNLKDAIGFDPTWIGNMLATVELYYQRGHYDKALETSDLFVKSIHAEDHRSGRQ 178 Query: 298 ---ENMDTFSNLLYVRSMKSELSYLA--HNLCEIDKY-RVETCCVIGNYYSLRSQHEKAA 351 + + K+ ++ L L I+ + + IG + + A Sbjct: 179 SKPNCLFLLLRAKLLYQKKNYMASLKIFQELLVINPVLQPDPRIGIGLCFWQLKDSKMAI 238 Query: 352 LYFQRALKLNP--RYLGAWTLMG---HEYMEMKNTSAAIQAYRHAI 392 +QRAL+LNP L+G + N +A+ A+ Sbjct: 239 KSWQRALQLNPKNTSASILVLLGEFRESFTNSTNDKTFKEAFTKAL 284 >3GYZ-A nrPDB Length = 151 Score = 34.8 bits (78), Expect = 0.12, Method: Composition-based stats. Identities = 26/136 (19%), Positives = 47/136 (34%), Gaps = 20/136 (14%) Query: 360 LNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCL 419 ++ Y A+ ++ A +R + + GL Y+I + Sbjct: 36 MDDIYSYAY-----DFYNKGRIEEAEVFFRFLCIYDFYNVDYIMGLAAIYQIKEQFQQAA 90 Query: 420 YYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQ 479 Y A L ND + G+C +L ++AK+C+ + EK+ + Sbjct: 91 DLYAVAFALGKNDYTPVFHTGQCQLRLKAPLKAKECFELVIQHSNDEKLKIK-------- 142 Query: 480 LTESEQAAQCYIKYIQ 495 AQ Y+ IQ Sbjct: 143 -------AQSYLDAIQ 151 >5GMK-d nrPDB Length = 687 Score = 34.4 bits (77), Expect = 0.14, Method: Composition-based stats. Identities = 30/191 (15%), Positives = 62/191 (32%), Gaps = 8/191 (4%) Query: 308 YVRSMKSELS-YLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLG 366 Y R ++E YL N ++ + + + +A F+RAL ++ ++ Sbjct: 46 YQRRKRTEYEGYLKRNRLDMGQ-----WIRYAQFEIEQHDMRRARSIFERALLVDSSFIP 100 Query: 367 AWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAH 426 W +++K + A AI R + WY E L Y + Sbjct: 101 LWIRYIDAELKVKCINHARNLMNRAISTLPRVDKLWYKYLIVEESLNNVEIVRSLYTKWC 160 Query: 427 QLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESEQA 486 L P + + + ++ Y + Y + + +K + + +E Sbjct: 161 SLEP-GVNAWNSFVDFEIRQKNWNGVREIYSK-YVMAHPQMQTWLKWVRFENRHGNTEFT 218 Query: 487 AQCYIKYIQDI 497 Y I + Sbjct: 219 RSVYSLAIDTV 229 >4GYO-A nrPDB Length = 373 Score = 34.4 bits (77), Expect = 0.14, Method: Composition-based stats. Identities = 27/134 (20%), Positives = 50/134 (37%), Gaps = 8/134 (5%) Query: 352 LYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEI 411 LY +R ++ G T + H + + +A++ R +E A+Y +G Sbjct: 174 LYGRRRVQCEFIIAGNLTDVYHHEKALTHLCSALEHARQ-LEEAYMIAAAYYNVGHCKYS 232 Query: 412 LKMPFYCLYYYRRAHQLRPNDSR-----MLVALGECYEKLNQLVEAKKCYWRAY--AVGD 464 L Y++ A + + + +L Y K + +A + Y R A Sbjct: 233 LGDYKEAEGYFKTAAAIFEEHNFQQAVQAVFSLTHIYCKEGKYDKAVEAYDRGIKSAAEW 292 Query: 465 VEKMALVKLAKLHE 478 + M L K +HE Sbjct: 293 EDDMYLTKFRLIHE 306 >6FUZ-A nrPDB Length = 337 Score = 34.4 bits (77), Expect = 0.14, Method: Composition-based stats. Identities = 17/138 (12%), Positives = 43/138 (31%), Gaps = 16/138 (11%) Query: 238 YTELQLIEEALQKYQNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQ----- 292 L+ +AL + + + ++ +AV Y +A + + Sbjct: 72 KDAANLLNDALAIREKTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVL 131 Query: 293 ---DPYRIENMDTFSNLLYVRSMKSELSYLAHN--------LCEIDKYRVETCCVIGNYY 341 P + ++ + L + E+ Y L D +T + + Y Sbjct: 132 GKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALGIYQTKLGPDDPNVAKTKNNLASCY 191 Query: 342 SLRSQHEKAALYFQRALK 359 + + ++A ++ L Sbjct: 192 LKQGKFKQAETLYKEILT 209 Score = 31.7 bits (70), Expect = 0.94, Method: Composition-based stats. Identities = 17/115 (14%), Positives = 33/115 (28%), Gaps = 16/115 (13%) Query: 396 KRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLR--------PNDSRMLVALGECYEKLN 447 L Y +RA ++R P+ ++ L L + Sbjct: 94 PAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQG 153 Query: 448 QLVEAKKCYWRAYAV--------GDVEKMALVKLAKLHEQLTESEQAAQCYIKYI 494 + E + Y RA + LA + + + +QA Y + + Sbjct: 154 KYEEVEYYYQRALGIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEIL 208 >5LJ5-S nrPDB Length = 687 Score = 33.6 bits (75), Expect = 0.22, Method: Composition-based stats. Identities = 24/164 (14%), Positives = 51/164 (31%), Gaps = 2/164 (1%) Query: 334 CCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIE 393 + + +A F+RAL ++ ++ W +++K + A AI Sbjct: 68 WIRYAQFEIEQHDMRRARSIFERALLVDSSFIPLWIRYIDAELKVKCINHARNLMNRAIS 127 Query: 394 VNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAK 453 R + WY E L Y + L P + + + + Sbjct: 128 TLPRVDKLWYKYLIVEESLNNVEIVRSLYTKWCSLEP-GVNAWNSFVDFEIRQKNWNGVR 186 Query: 454 KCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYIKYIQDI 497 + Y + Y + + +K + + +E Y I + Sbjct: 187 EIYSK-YVMAHPQMQTWLKWVRFENRHGNTEFTRSVYSLAIDTV 229 Score = 32.5 bits (72), Expect = 0.51, Method: Composition-based stats. Identities = 51/321 (15%), Positives = 110/321 (34%), Gaps = 35/321 (10%) Query: 97 KEYDRAAHFLHGCNSKKAYFLYMYSRYLSGEKKKDDETVDSLGPLEKGQVKNEALRELRV 156 +EY+R++ K + + L EK+ D + +E+ + + Sbjct: 258 QEYERSSALYQIAIEKWPSNQLLKAGLLDFEKQFGD-----INSIEETISYKRKMEYETI 312 Query: 157 ELSKKHQARELDGFGLYLYGVVLRKLDLVKEAIDVFVEATHVLPLHWGAWLELCNLITDK 216 + + + D + LY LDL+ E+ + T + EL Sbjct: 313 LSNNAY---DYDTWWLY--------LDLISESFPKQIMQTFEKAIVDSRPKELS------ 355 Query: 217 EMLKFLSLPDTWMKEFFLAHIYTELQLIEEALQKYQNLIDVGFSKSSYIVSQIAVAY--- 273 + +++ WM+ ++ ++ EL+ + +Q LID + S+I + Y Sbjct: 356 KNVQWKRYIYLWMR--YICYVELELENSLLEEELFQRLIDDIIPHKHFTFSKIWLMYAKF 413 Query: 274 -HNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDKYRVE 332 D+ KA I + P + + + L + + E ++ Sbjct: 414 LIRHDDVPKARKILGKAIGLCP-KAKTFKGYIELEVKLKEFDRVRKIYEKFIEFQPSDLQ 472 Query: 333 TCCVIGNYYSLRSQHEKAALYFQRALKLNPRYL--GAWTLMGHEYM----EMKNTSAAIQ 386 G ++ + AL N +L A ++ +Y+ E + A + Sbjct: 473 IWSQYGELEENLGDWDRVRGIYTIALDENSDFLTKEAKIVLLQKYITFETESQEFEKARK 532 Query: 387 AYRHAIEVNKRDYRAWYGLGQ 407 YR +E+N+ ++W Sbjct: 533 LYRRYLELNQYSPQSWIEFAM 553 >6ICZ-I nrPDB Length = 855 Score = 33.6 bits (75), Expect = 0.27, Method: Composition-based stats. Identities = 47/278 (16%), Positives = 88/278 (31%), Gaps = 54/278 (19%) Query: 323 LCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRAL----------KLNPRYLG------ 366 L + C + +YY EKA ++ A+ ++ Y Sbjct: 248 LTRFTDQLGKLWCSLADYYIRSGHFEKARDVYEEAIRTVMTVRDFTQVFDSYAQFEESMI 307 Query: 367 -----AWTLMGHEYMEMKNTSAAIQAYRHAI------------EVNKRDYRAWYGLGQTY 409 + +G E + + + + I N W+ + Sbjct: 308 AAKMETASELGREEEDDVDLELRLARFEQLISRRPLLLNSVLLRQNPHHVHEWHKRVALH 367 Query: 410 EILKMPFYCLYYYRRAHQ-LRPNDS-----RMLVALGECYEKLNQLVEAKKCYWRAYAVG 463 P + Y A Q + P + + VA + YE QL +A+ +A Sbjct: 368 --QGRPREIINTYTEAVQTVDPFKATGKPHTLWVAFAKFYEDNGQLDDARVILEKATK-- 423 Query: 464 DVEKMALVKLAKLHEQLTESEQAAQCYIKYIQDIYSCGEI----VEHLEESTAFRYLAQY 519 V + LA + Q E E + Y + ++ + + E+ + S + + Sbjct: 424 -VNFKQVDDLASVWCQCGELELRHENYDEALRLLRKATALPARRAEYFDGSEPVQ--NRV 480 Query: 520 YFKCKLWDEASTCAQKCCAFNDTREEGKALLRQILQLR 557 Y K+W + + F T KA+ +IL LR Sbjct: 481 YKSLKVWSMLADLEESLGTFQST----KAVYDRILDLR 514 Score = 31.7 bits (70), Expect = 0.83, Method: Composition-based stats. Identities = 18/110 (16%), Positives = 39/110 (35%), Gaps = 12/110 (10%) Query: 347 HEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNK--RDYRAWYG 404 HE+A ++ + +L W M+ + + + A+ + R W Sbjct: 99 HERAFVFMHKMPRL-------WLDYCQFLMDQGRVTHTRRTFDRALRALPITQHSRIWPL 151 Query: 405 LGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKK 454 + +P + YRR +L P + + + ++L EA + Sbjct: 152 YLRFLRSHPLPETAVRGYRRFLKLSPESAEEYIEY---LKSSDRLDEAAQ 198 >1ZU2-A nrPDB Length = 158 Score = 32.8 bits (73), Expect = 0.45, Method: Composition-based stats. Identities = 16/100 (16%), Positives = 34/100 (34%), Gaps = 21/100 (21%) Query: 361 NPRYLGAWTLMGHEYMEMKN----------TSAAIQAYRHAIEVNKRDYRAWYGLGQTY- 409 NP T G +E+ AI + A+ ++ + A + +G Y Sbjct: 32 NPLDADNLTRWGGVLLELSQFHSISDAKQMIQEAITKFEEALLIDPKKDEAVWCIGNAYT 91 Query: 410 ----------EILKMPFYCLYYYRRAHQLRPNDSRMLVAL 439 E ++++A +P+++ L +L Sbjct: 92 SFAFLTPDETEAKHNFDLATQFFQQAVDEQPDNTHYLKSL 131 >3TJZ-B nrPDB Length = 355 Score = 32.5 bits (72), Expect = 0.54, Method: Composition-based stats. Identities = 26/74 (35%), Positives = 36/74 (48%), Gaps = 5/74 (6%) Query: 528 EASTCAQKCCAFNDTR---EEGKALLRQILQLRNQGE-TPTTEVPAPFFLPASLSANNTP 583 E S Q+ FN+T + +L +IL L NQGE TTE FF L +N P Sbjct: 23 EKSAVLQEARVFNETPINPRKCAHILTKILYLINQGEHLGTTEATEAFFAMTKLFQSNDP 82 Query: 584 T-RRVSPLNLSSVT 596 T RR+ L + ++ Sbjct: 83 TLRRMCYLTIKEMS 96 >5JHE-A nrPDB Length = 397 Score = 32.5 bits (72), Expect = 0.56, Method: Composition-based stats. Identities = 18/91 (19%), Positives = 36/91 (39%), Gaps = 8/91 (8%) Query: 368 WTLMGHEYMEMKNTSAAIQAYRHAIEV----NKRDYRAWYGLGQTYEILKMPFYCLYYYR 423 + + ++ AI + +E+ N+ +A+Y G +Y K L Y Sbjct: 299 YLNLSLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYI 358 Query: 424 RAHQLRPNDSRMLVALGECYEKLNQLVEAKK 454 + P+D + + E +N+L+E K Sbjct: 359 FCKEKNPDDEV----IEQRIEYVNRLIEENK 385 Score = 30.1 bits (66), Expect = 2.5, Method: Composition-based stats. Identities = 14/59 (23%), Positives = 26/59 (44%), Gaps = 4/59 (6%) Query: 344 RSQHEKAALYFQRALKLN--PR--YLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRD 398 +++ A +Y L+++ P A+ G+ Y++ K A+Q Y E N D Sbjct: 309 LERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYIFCKEKNPDD 367 >5A1Y-E nrPDB Length = 874 Score = 32.5 bits (72), Expect = 0.59, Method: Composition-based stats. Identities = 26/74 (35%), Positives = 36/74 (48%), Gaps = 5/74 (6%) Query: 528 EASTCAQKCCAFNDTR---EEGKALLRQILQLRNQGE-TPTTEVPAPFFLPASLSANNTP 583 E S Q+ FN+T + +L +IL L NQGE TTE FF L +N P Sbjct: 23 EKSAVLQEARVFNETPINPRKCAHILTKILYLINQGEHLGTTEATEAFFAMTKLFQSNDP 82 Query: 584 T-RRVSPLNLSSVT 596 T RR+ L + ++ Sbjct: 83 TLRRMCYLTIKEMS 96 >5WLC-LP nrPDB Length = 440 Score = 32.1 bits (71), Expect = 0.67, Method: Composition-based stats. Identities = 12/89 (13%), Positives = 29/89 (32%), Gaps = 4/89 (4%) Query: 354 FQRALKLNPRYLGAWTLMGHEYMEMKN---TSAAIQAYRHAIEVNKRDYRAWYGLGQ-TY 409 +QR P+ L W + + N Y ++++ + W + Y Sbjct: 96 YQRGTNKFPQDLKFWAMYLNYMKARGNQTSYKKIHNIYNQLLKLHPTNVDIWISCAKYEY 155 Query: 410 EILKMPFYCLYYYRRAHQLRPNDSRMLVA 438 E+ C ++ + P+ ++ Sbjct: 156 EVHANFKSCRNIFQNGLRFNPDVPKLWYE 184 >6FRK-r nrPDB Length = 605 Score = 32.1 bits (71), Expect = 0.79, Method: Composition-based stats. Identities = 38/238 (15%), Positives = 79/238 (33%), Gaps = 19/238 (7%) Query: 273 YHNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDKYRVE 332 Y D +AL N++ + + + + L E + + ++ Sbjct: 21 YGQNGDFTRALKTVNKILQINKDDVTALHCKVVCLIQNGSFKEALNVINTHTKVLANNSL 80 Query: 333 TCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAI 392 + Y L ++ E A + A + + L G ++ + YR + Sbjct: 81 SFEKAYCEYRL-NRIENALKTIESANQQTDKLKE---LYGQVLYRLERYDECLAVYRDLV 136 Query: 393 EVNKRDYRAW--YGLGQTYEILKM----PFYCLYYYRRAHQLRPNDSRMLVALGECYEKL 446 ++ DY L L H+L N + L+ G+ + + Sbjct: 137 RNSQDDYDEERKTNLSAVVAAQSNWEKVVPENLGLQEGTHELCYNAACALIGQGQLSQAM 196 Query: 447 NQLVEAKKCYWRAYAVGD--VEKMALVKLAKLHEQL-------TESEQAAQCYIKYIQ 495 L +A+ R+ + E+ +LA +H Q+ +E+A Q Y + I+ Sbjct: 197 KILQKAEDLCRRSLSEDSDGTEEDPQAELAIIHGQMAYILQLQGRTEEALQLYNQIIK 254 Score = 30.9 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 29/184 (15%), Positives = 60/184 (32%), Gaps = 21/184 (11%) Query: 231 EFFLAHIYTELQLIEEALQKYQNLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELR 290 F A+ L IE AL+ I+ ++ + + + D+ L+++ +L Sbjct: 81 SFEKAYCEYRLNRIENALK----TIESANQQTDKLKELYGQVLYRLERYDECLAVYRDLV 136 Query: 291 KQDPYRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKA 350 + + + V + + + NL + + E C + Q +A Sbjct: 137 RNSQDDYDEERKTNLSAVVAAQSNWEKVVPENLG-LQEGTHELCYNAACALIGQGQLSQA 195 Query: 351 ALYFQRA--------------LKLNPRYLGAWT--LMGHEYMEMKNTSAAIQAYRHAIEV 394 Q+A + +P+ A M + T A+Q Y I++ Sbjct: 196 MKILQKAEDLCRRSLSEDSDGTEEDPQAELAIIHGQMAYILQLQGRTEEALQLYNQIIKL 255 Query: 395 NKRD 398 D Sbjct: 256 KPTD 259 >2IF4-A nrPDB Length = 338 Score = 30.9 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 29/203 (14%), Positives = 68/203 (33%), Gaps = 32/203 (15%) Query: 291 KQDPYRIENMDTFSNLLYV----------RSMKSELSYLAHNLCEIDKYRVETCCVIGNY 340 K+ + N+ ++LLY + + D+ +++ GN Sbjct: 134 KEGNFSFPNVPPMADLLYEVEVIGFDETKEGKARSDMTVEERIGAADRRKMD-----GNS 188 Query: 341 YSLRSQHEKAALYFQRAL---------KLNPRYL--------GAWTLMGHEYMEMKNTSA 383 + E+A ++ A+ +L +Y + +++K Sbjct: 189 LFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAACLIKLKRYDE 248 Query: 384 AIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECY 443 AI + +++ +A + G+ L +R+A + P+D + L Sbjct: 249 AIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPDDKAIRRELRALA 308 Query: 444 EKLNQLVEAKKCYWRAYAVGDVE 466 E+ L + +K ++ G E Sbjct: 309 EQEKALYQKQKEMYKGIFKGKDE 331 >3LY9-A nrPDB Length = 372 Score = 30.5 bits (67), Expect = 1.9, Method: Composition-based stats. Identities = 14/69 (20%), Positives = 25/69 (36%), Gaps = 1/69 (1%) Query: 368 WTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQ 427 + + + T + QA I++ + LG+ YE+ M Y A Sbjct: 280 YQIKAVSALVKGKTDESYQAINTGIDLEMSWLN-YVLLGKVYEMKGMNREAANAYLTAFN 338 Query: 428 LRPNDSRML 436 LRP + + Sbjct: 339 LRPGANTLY 347 >5WRW-A nrPDB Length = 163 Score = 30.1 bits (66), Expect = 3.0, Method: Composition-based stats. Identities = 18/128 (14%), Positives = 41/128 (32%), Gaps = 4/128 (3%) Query: 273 YHNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDKYRVE 332 Y D +AL N++ + + + + L E + + ++ Sbjct: 21 YGQNGDFTRALKTVNKILQINKDDVTALHCKVVCLIQNGSFKEALNVINTHTKVLANNSL 80 Query: 333 TCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAI 392 + Y L ++ E A + A + + L G ++ + YR + Sbjct: 81 SFEKAYCEYRL-NRIENALKTIESANQQTDKLKE---LYGQVLYRLERYDECLAVYRDLV 136 Query: 393 EVNKRDYR 400 ++ DY Sbjct: 137 RNSQDDYD 144 >6G70-A nrPDB Length = 670 Score = 29.8 bits (65), Expect = 3.2, Method: Composition-based stats. Identities = 15/118 (12%), Positives = 37/118 (31%), Gaps = 1/118 (0%) Query: 376 MEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRM 435 + + + +E+N +D+ W L Q E + + P Sbjct: 75 EAEGDFPPEFEKFWKTVEMNPQDFTGWVYLLQYVEQENHLMAARKAFDKFFVHYPYCYGY 134 Query: 436 LVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVK-LAKLHEQLTESEQAAQCYIK 492 + ++ + + ++ + Y R + + + L E L +Q I+ Sbjct: 135 WKKYADLEKRHDNIKQSDEVYRRGLQAIPLSVDLWIHYINFLKETLDPGDQETNTTIR 192 >5UWZ-A nrPDB Length = 243 Score = 29.8 bits (65), Expect = 3.5, Method: Composition-based stats. Identities = 12/73 (16%), Positives = 21/73 (28%), Gaps = 5/73 (6%) Query: 363 RYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYY 422 Y A++ + +E + A Y E+ A L F Sbjct: 17 TYRDAYSRINAIVLEGER--EAHANYLTLAEMLPDHAEALKKLAAM---ENRHFKGFQSC 71 Query: 423 RRAHQLRPNDSRM 435 R ++ P+D Sbjct: 72 ARNLEVTPDDPFA 84 >6N3Q-F nrPDB Length = 193 Score = 29.4 bits (64), Expect = 5.2, Method: Composition-based stats. Identities = 27/141 (19%), Positives = 43/141 (30%), Gaps = 19/141 (13%) Query: 361 NPRYLGAWTLMGHEYMEMKNTS-----AAIQAYRHAIEVNKRDYRAWYGLG-----QTYE 410 P + + G MKN A++ AIE+ +R W + Sbjct: 49 QPNEALSKMIKGLFESGMKNLQQKKLNEALKNVSLAIEMAQRKRAPWEAFAIQLPELHFM 108 Query: 411 ILKMPFYCLYYYRRAHQLRPND---------SRMLVALGECYEKLNQLVEAKKCYWRAYA 461 + CL + L+ D + V +C KL Q EA+ R A Sbjct: 109 LRSKIDLCLILGKHLEALQDLDFLLGTGLIQPDVFVRKADCLLKLRQWEEARATCERGLA 168 Query: 462 VGDVEKMALVKLAKLHEQLTE 482 + + L + L E Sbjct: 169 LAPEDMKLRALLIETARNLAE 189 >6HTS-R nrPDB Length = 356 Score = 28.6 bits (62), Expect = 8.9, Method: Composition-based stats. Identities = 20/55 (36%), Positives = 28/55 (50%), Gaps = 6/55 (10%) Query: 25 DFSDLREIKKQLLLIAGLTRERGLLHSSKWSAELAFSLPALPLAELQPPPPITEE 79 D DL++ + LL A R+R LL ++ L P+AE PPP +TEE Sbjct: 163 DNGDLKKEINERLLTA---RQRALLQKARSQPSPMLPL---PVAEGCPPPALTEE 211 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.315 0.124 0.315 Lambda K H 0.267 0.0380 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 19,765,600 Number of Sequences: 36641 Number of extensions: 740832 Number of successful extensions: 2477 Number of sequences better than 10.0: 77 Number of HSP's better than 10.0 without gapping: 67 Number of HSP's successfully gapped in prelim test: 41 Number of HSP's that attempted gapping in prelim test: 2099 Number of HSP's gapped (non-prelim): 254 length of query: 597 length of database: 10,336,785 effective HSP length: 103 effective length of query: 494 effective length of database: 6,562,762 effective search space: 3242004428 effective search space used: 3242004428 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 62 (28.6 bits)