BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9UJM8 (370 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2RDU-A nrPDB 759 0.0 1AL8-A nrPDB 403 e-113 5ZBN-A nrPDB 394 e-110 3SGZ-A nrPDB 325 2e-89 1QCW-A nrPDB 256 9e-69 1SZG-A nrPDB 256 1e-68 2A85-A nrPDB 239 2e-63 6DVI-A nrPDB 227 8e-60 6BFG-A nrPDB 215 3e-56 2J6X-A nrPDB 212 2e-55 2CDH-0 nrPDB 178 3e-45 3SR7-A nrPDB 48 8e-06 5LSM-A nrPDB 40 0.001 2ZRW-A nrPDB 40 0.001 4N02-A nrPDB 39 0.004 1P0K-A nrPDB 39 0.004 3FFS-A nrPDB 35 0.068 5UQG-A nrPDB 35 0.076 1VRD-A nrPDB 34 0.092 1EEP-A nrPDB 34 0.10 4QJ1-A nrPDB 34 0.12 3TSB-A nrPDB 33 0.15 4MJM-A nrPDB 33 0.17 3R2G-A nrPDB 33 0.24 1XI3-A nrPDB 33 0.27 4FEZ-A nrPDB 32 0.40 2CU0-A nrPDB 32 0.47 4FXS-A nrPDB 32 0.49 1WNF-A nrPDB 32 0.60 2GGG-A nrPDB 32 0.62 1ZFJ-A nrPDB 31 0.68 5ICQ-A nrPDB 31 0.88 5CSS-A nrPDB 30 1.2 5AHL-A nrPDB 30 1.2 4DQW-A nrPDB 30 1.6 2H6R-A nrPDB 30 1.6 6I0M-A nrPDB 30 1.7 2IHN-A nrPDB 30 1.7 1UUO-A nrPDB 30 2.0 5UPU-A nrPDB 29 2.5 1JCN-A nrPDB 29 2.5 3N2S-A nrPDB 29 2.6 1WNB-A nrPDB 29 2.7 1IUQ-A nrPDB 29 2.7 4TWE-A nrPDB 29 3.8 1TJR-A nrPDB 29 4.1 5Z9Y-A nrPDB 28 4.3 6C43-A nrPDB 28 4.5 4XTI-A nrPDB 28 5.4 4Z87-A nrPDB 28 5.9 1YPF-A nrPDB 28 6.2 1U7N-A nrPDB 28 6.3 3U2O-A nrPDB 28 6.6 4JDY-A nrPDB 28 9.4 4AF0-B nrPDB 27 9.9 1HG3-A nrPDB 27 10.0 >2RDU-A nrPDB Length = 387 Score = 759 bits (1961), Expect = 0.0, Method: Compositional matrix adjust. Identities = 370/370 (100%), Positives = 370/370 (100%) Query: 1 MLPRLICINDYEQHAKSVLPKSIYDYYRSGANDEETLADNIAAFSRWKLYPRMLRNVAET 60 MLPRLICINDYEQHAKSVLPKSIYDYYRSGANDEETLADNIAAFSRWKLYPRMLRNVAET Sbjct: 18 MLPRLICINDYEQHAKSVLPKSIYDYYRSGANDEETLADNIAAFSRWKLYPRMLRNVAET 77 Query: 61 DLSTSVLGQRVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSWATSSIEEVAE 120 DLSTSVLGQRVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSWATSSIEEVAE Sbjct: 78 DLSTSVLGQRVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSWATSSIEEVAE 137 Query: 121 AGPEALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKLPPQ 180 AGPEALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKLPPQ Sbjct: 138 AGPEALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKLPPQ 197 Query: 181 LRMKNFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVAKGILR 240 LRMKNFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVAKGILR Sbjct: 198 LRMKNFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVAKGILR 257 Query: 241 GDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDV 300 GDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDV Sbjct: 258 GDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDV 317 Query: 301 LKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDKTLV 360 LKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDKTLV Sbjct: 318 LKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDKTLV 377 Query: 361 RKNPLAVSKI 370 RKNPLAVSKI Sbjct: 378 RKNPLAVSKI 387 >1AL8-A nrPDB Length = 359 Score = 403 bits (1036), Expect = e-113, Method: Compositional matrix adjust. Identities = 201/353 (56%), Positives = 266/353 (75%), Gaps = 4/353 (1%) Query: 8 INDYEQHAKSVLPKSIYDYYRSGANDEETLADNIAAFSRWKLYPRMLRNVAETDLSTSVL 67 +N+YE AK LPK +YDYY SGA D+ TLA+N AFSR PR+L +V D++T++L Sbjct: 6 VNEYEAIAKQKLPKMVYDYYASGAEDQWTLAENRNAFSRILFRPRILIDVTNIDMTTTIL 65 Query: 68 GQRVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSWATSSIEEVAEAGPEALR 127 G ++SMPI + TAMQ+MAH +GE AT RA + GT M LSSWATSS+EEVA GP +R Sbjct: 66 GFKISMPIMIAPTAMQKMAHPEGEYATARAASAAGTIMTLSSWATSSVEEVASTGP-GIR 124 Query: 128 WLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKLPPQLRMKNFE 187 + QLY+YKDR V +LVR+AE+ G+KAI +TVDTP LG R D++NRF LPP L +KNFE Sbjct: 125 FFQLYVYKDRNVVAQLVRRAERAGFKAIALTVDTPRLGRREADIKNRFVLPPFLTLKNFE 184 Query: 188 TSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVAKGILRGDDAREA 247 L + N DSGL++YVA ID S+SW+D+ WL+ +TSLPI+ KG++ +DAR A Sbjct: 185 GIDLGKMDKAN---DSGLSSYVAGQIDRSLSWKDVAWLQTITSLPILVKGVITAEDARLA 241 Query: 248 VKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALG 307 V+HG GI+VSNHGARQLD VPATI L E+V+A +G++ VFLDGGVR+GTDV KALALG Sbjct: 242 VQHGAAGIIVSNHGARQLDYVPATIMALEEVVKAAQGRIPVFLDGGVRRGTDVFKALALG 301 Query: 308 AKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDKTLV 360 A VF+GRP+V+ LA +GE GV+ VL+++++EF L MALSGC+++K I ++ + Sbjct: 302 AAGVFIGRPVVFSLAAEGEAGVKKVLQMMRDEFELTMALSGCRSLKEISRSHI 354 >5ZBN-A nrPDB Length = 371 Score = 394 bits (1011), Expect = e-110, Method: Compositional matrix adjust. Identities = 197/353 (55%), Positives = 265/353 (75%), Gaps = 4/353 (1%) Query: 8 INDYEQHAKSVLPKSIYDYYRSGANDEETLADNIAAFSRWKLYPRMLRNVAETDLSTSVL 67 + +YE AK LPK ++DYY SGA D+ TLA+N AFSR PR+L +V++ D+ST+VL Sbjct: 7 VMEYEAIAKKKLPKMVFDYYASGAEDQWTLAENRNAFSRILFRPRILIDVSKIDMSTTVL 66 Query: 68 GQRVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSWATSSIEEVAEAGPEALR 127 G ++SMPI + TAMQ+MAH +GE AT RA + GT M LSSWATSS+EEVA GP +R Sbjct: 67 GFKISMPIMIAPTAMQKMAHPEGEYATARAASAAGTIMTLSSWATSSVEEVASTGP-GIR 125 Query: 128 WLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKLPPQLRMKNFE 187 + QLY+YKDR V +LVR+AE+ G+KAI +TVDTP LG R D++NRF LPP L +KNFE Sbjct: 126 FFQLYVYKDRNVVAQLVRRAERAGFKAIALTVDTPRLGRREADIKNRFVLPPFLTLKNFE 185 Query: 188 TSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVAKGILRGDDAREA 247 L + + DSGLA+YVA ID ++SW+D++WL+ +TSLPI+ KG+L +DAR A Sbjct: 186 GLDLG---KMDQASDSGLASYVAGQIDRTLSWKDVQWLQTITSLPILVKGVLTAEDARLA 242 Query: 248 VKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALG 307 V+ G GI+VSNHGARQLD VP+TI L E+V+A +G++ VFLDGGVR+GTDV KALALG Sbjct: 243 VQAGAAGIIVSNHGARQLDYVPSTIMALEEVVKAAQGRIPVFLDGGVRRGTDVFKALALG 302 Query: 308 AKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDKTLV 360 A +F+GRP+V+ LA +GE G++ VL++L++EF L MALSGC+++ I + + Sbjct: 303 ASGIFIGRPVVFSLAAEGEAGIKKVLQMLRDEFELTMALSGCRSLNEITRNHI 355 >3SGZ-A nrPDB Length = 352 Score = 325 bits (834), Expect = 2e-89, Method: Compositional matrix adjust. Identities = 164/357 (45%), Positives = 232/357 (64%), Gaps = 10/357 (2%) Query: 5 LICINDYEQHAKSVLPKSIYDYYRSGANDEETLADNIAAFSRWKLYPRMLRNVAETDLST 64 L+C+ D++ HA+ L K+ +D+ A+D T ++NIAAF R +L PR LR++++ D T Sbjct: 2 LVCLADFKAHAQKQLSKTSWDFIEGEADDGITYSENIAAFKRIRLRPRYLRDMSKVDTRT 61 Query: 65 SVLGQRVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSWATSSIEEVAEAGPE 124 ++ GQ +S PIC+ TA +A DGE +T RA Q ++SS+A+ S+E++ A PE Sbjct: 62 TIQGQEISAPICISPTAFHSIAWPDGEKSTARAAQEANICYVISSYASYSLEDIVAAAPE 121 Query: 125 ALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKLPPQLRMK 184 RW QLY+ D + K++V++AE +G+KA+ +T+DTP LGNR D RN+ L Sbjct: 122 GFRWFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQLNLEA----- 176 Query: 185 NFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVAKGILRGDDA 244 N + L EE + KA S W D+ L+ +T LPI+ KGIL +DA Sbjct: 177 NILKAALRALKEEK--PTQSVPVLFPKA---SFCWNDLSLLQSITRLPIILKGILTKEDA 231 Query: 245 REAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKAL 304 A+KH + GI+VSNHG RQLD V A+ID L E+V AV+GK+EV++DGGVR GTDVLKAL Sbjct: 232 ELAMKHNVQGIVVSNHGGRQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKAL 291 Query: 305 ALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDKTLVR 361 ALGA+ +F+GRPI+WGLA +GE GV++VL+IL E M LSGCQ+V I L++ Sbjct: 292 ALGARCIFLGRPILWGLACKGEDGVKEVLDILTAELHRCMTLSGCQSVAEISPDLIQ 348 >1QCW-A nrPDB Length = 410 Score = 256 bits (655), Expect = 9e-69, Method: Compositional matrix adjust. Identities = 144/364 (39%), Positives = 221/364 (60%), Gaps = 25/364 (6%) Query: 2 LPRLICINDYEQHAKSVLPKSIYDYYRSGANDEETLADNIAAFSRWKLYPRMLRNVAETD 61 L +I + D+E A L K + YY SGANDE T +N A+ R P++L +V + D Sbjct: 18 LDNIINLYDFEYLASQTLTKQAWAYYSSGANDEVTHRENHNAYHRIFFKPKILVDVRKVD 77 Query: 62 LSTSVLGQRVSMPICVGATAMQRMAH-VDGELATVRACQSLGTGM-----MLSSWATSSI 115 +ST +LG V +P V ATA+ ++ + ++GE R C G G+ M+S+ A+ S Sbjct: 78 ISTDMLGSHVDVPFYVSATALCKLGNPLEGEKDVARGC---GQGVTKVPQMISTLASCSP 134 Query: 116 EEVAEAGP--EALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRN 173 EE+ EA P + ++W QLY+ DR++T LV+ EK+G KA+FVTVD P LG + D++ Sbjct: 135 EEIIEAAPSDKQIQWYQLYVNSDRKITDDLVKNVEKLGVKALFVTVDAPSLGQKEKDMKL 194 Query: 174 RFKLPPQLRMKNFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPI 233 +F + + + N + G + ++K IDPS++W+DI+ L++ T LPI Sbjct: 195 KF---------SNTKAGFKAMKKTNVEESQGASRALSKFIDPSLTWKDIEELKKKTKLPI 245 Query: 234 VAKGILRGDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVE-----GKVEV 288 V KG+ R +D +A + G++G+++SNHG RQLD A I+VL E + +E K+EV Sbjct: 246 VIKGVQRTEDVIKAAEIGVSGVVLSNHGGRQLDFSRAPIEVLAETMPILEQRNLKDKLEV 305 Query: 289 FLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSG 348 F+DGGVR+GTDVLKAL LGAK V +GRP ++ + G GV+ +EIL++E ++M L G Sbjct: 306 FVDGGVRRGTDVLKALCLGAKGVGLGRPFLYANSCYGRNGVEKAIEILRDEIEMSMRLLG 365 Query: 349 CQNV 352 ++ Sbjct: 366 VTSI 369 >1SZG-A nrPDB Length = 511 Score = 256 bits (653), Expect = 1e-68, Method: Compositional matrix adjust. Identities = 147/368 (39%), Positives = 221/368 (60%), Gaps = 33/368 (8%) Query: 2 LPRLICINDYEQHAKSVLPKSIYDYYRSGANDEETLADNIAAFSRWKLYPRMLRNVAETD 61 L +I + D+E A L K + YY SGANDE T +N A+ R P++L +V + D Sbjct: 119 LDNIINLYDFEYLASQTLTKQAWAYYSSGANDEVTHRENHNAYHRIFFKPKILVDVRKVD 178 Query: 62 LSTSVLGQRVSMPICVGATAMQRMAH-VDGELATVRACQSLGTGM-----MLSSWATSSI 115 +ST +LG V +P V AT + ++ + ++GE R C G G+ M+S+ A+ S Sbjct: 179 ISTDMLGSHVDVPFYVSATGLCKLGNPLEGEKDVARGC---GQGVTKVPQMISTAASCSP 235 Query: 116 EEVAEAGP--EALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRN 173 EE+ EA P + ++W QLY+ DR++T LV+ EK+G KA+FVTVD P LG R D++ Sbjct: 236 EEIIEAAPSDKQIQWYQLYVNSDRKITDDLVKNVEKLGVKALFVTVDAPSLGQREKDMKL 295 Query: 174 RFKL----PPQLRMKNFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLT 229 +F P ++ N E S G + ++K IDPS++W+DI+ L++ T Sbjct: 296 KFSNTKAGPKAMKKTNVEES-------------QGASRALSKFIDPSLTWKDIEELKKKT 342 Query: 230 SLPIVAKGILRGDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVE-----G 284 LPIV KG+ R +D +A + G++G+++SNHG RQLD A I+VL E + +E Sbjct: 343 KLPIVIKGVQRTEDVIKAAEIGVSGVVLSNHGGRQLDFSRAPIEVLAETMPILEQRNLKD 402 Query: 285 KVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAM 344 K+EVF+DGGVR+GTDVLKAL LGAK V +GRP ++ + G GV+ +EIL++E ++M Sbjct: 403 KLEVFVDGGVRRGTDVLKALCLGAKGVGLGRPFLYANSCYGRNGVEKAIEILRDEIEMSM 462 Query: 345 ALSGCQNV 352 L G ++ Sbjct: 463 RLLGVTSI 470 >2A85-A nrPDB Length = 380 Score = 239 bits (609), Expect = 2e-63, Method: Compositional matrix adjust. Identities = 135/352 (38%), Positives = 202/352 (57%), Gaps = 7/352 (1%) Query: 1 MLPRLICINDYEQHAKSVLPKSIYDYYRSGANDEETLADNIAAFSRWKLYPRMLRNVAET 60 M L + DY + A+ LPK +YDY GA DE + N F +W+ P+ L +V+ Sbjct: 1 MSQNLFNVEDYRKLAQKRLPKMVYDYLEGGAEDEYGVKHNRDVFQQWRFKPKRLVDVSRR 60 Query: 61 DLSTSVLGQRVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSWATSSIEEVAE 120 L VLG+R SMP+ +G TA+ G+LA RA G +LS+ + SIE++A Sbjct: 61 SLQAEVLGKRQSMPLLIGPTALNGALWPKGDLALARAATKAGIPFVLSTASNMSIEDLAR 120 Query: 121 AGPEALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKLPPQ 180 L W QLY+ RE+ + +V +A GY + +T D G R D+ NRFK+PP Sbjct: 121 QCDGDL-WFQLYVIH-REIAQGMVLKALHTGYTTLVLTTDVAVNGYRERDLHNRFKIPPF 178 Query: 181 LRMKNFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVAKGILR 240 L +KNFE L + N AA +++ +D S +WE ++WLR L ++ KG+L Sbjct: 179 LTLKNFEGIDLGKMDKANL---EMQAALMSRQMDASFNWEALRWLRDLWPHKLLVKGLLS 235 Query: 241 GDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDV 300 +DA + G +G+++SNHG RQLD + ++VL + V A GK V +D G R+G+D+ Sbjct: 236 AEDADRCIAEGADGVILSNHGGRQLDCAISPMEVLAQSV-AKTGK-PVLIDSGFRRGSDI 293 Query: 301 LKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNV 352 +KALALGA+AV +GR ++GLA +GE GV +VL +LK + +A GC ++ Sbjct: 294 VKALALGAEAVLLGRATLYGLAARGETGVDEVLTLLKADIDRTLAQIGCPDI 345 >6DVI-A nrPDB Length = 394 Score = 227 bits (578), Expect = 8e-60, Method: Compositional matrix adjust. Identities = 130/356 (36%), Positives = 191/356 (53%), Gaps = 13/356 (3%) Query: 10 DYEQHAKSVLPKSIYDYYRSGANDEETLADNIAAFSRWKLYPRMLRNVAETDLSTSVLGQ 69 D+E HA+ LP + Y G+ DE T N+ AF W L PRML E DLS + G+ Sbjct: 29 DWEAHAQQALPPGVLSYVAGGSGDEHTQRANVEAFKHWGLMPRMLMAATERDLSVELWGK 88 Query: 70 RVSMPICVGATAMQRMAHVDG--ELATVRACQSLGTGMMLSSWATSSIEEVAEAGPEALR 127 + P+ + + DG + A+ +A G + S+ A SS+E++ + + Sbjct: 89 TWAAPMFFAPIGVIALCAQDGHGDAASAQASARTGVPYITSTLAVSSLEDIRKHAGDTPA 148 Query: 128 WLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVR-NRFKLPPQLRMKNF 186 + QLY +DR++ + +R+AE+ GY + +T+DT G R D+ + F L + N+ Sbjct: 149 YFQLYYPEDRDLAESFIRRAEEAGYDGLVITLDTWIFGWRPRDLTISNFPFLRGLCLTNY 208 Query: 187 ETSTL--------SFSPEENFGDDSGLAA-YVAKAIDPSISWEDIKWLRRLTSLPIVAKG 237 T + S E D+ LAA + S++WEDI W+R +T +P++ KG Sbjct: 209 VTDPVFQKKFKAHSGVEAEGLRDNPRLAADFWHGLFGHSVTWEDIDWVRSITKMPVILKG 268 Query: 238 ILRGDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKG 297 I DDAR AV G++GI SNHG RQ +G +D LPE+V+A G V D G+R G Sbjct: 269 IQHPDDARRAVDSGVDGIYCSNHGGRQANGGLPALDCLPEVVKA-SGDTPVLFDSGIRTG 327 Query: 298 TDVLKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVK 353 DV+KALA+GA AV +GRP WG A G KG++ V L E L MA+ G +N+K Sbjct: 328 ADVVKALAMGASAVGIGRPYAWGAALGGSKGIEHVARSLLAEADLIMAVDGYRNLK 383 >6BFG-A nrPDB Length = 399 Score = 215 bits (547), Expect = 3e-56, Method: Compositional matrix adjust. Identities = 133/381 (34%), Positives = 200/381 (52%), Gaps = 46/381 (12%) Query: 1 MLPRLICINDYEQHAKSVLPKSIYDYYRSGANDEETLADNIAAFSRWKLYPRMLRNVAET 60 M L + DY + + LPK +YDY GA DE + N F +W+ P+ L +V+ Sbjct: 1 MSQNLFNVEDYRKLRQKRLPKMVYDYLEGGAEDEYGVKHNRDVFQQWRFKPKRLVDVSRR 60 Query: 61 DLSTSVLGQRVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSWATSSIEEVAE 120 L VLG+R SMP+ +G T + G+LA RA G +LS+ + SIE++A Sbjct: 61 SLQAEVLGKRQSMPLLIGPTGLNGALWPKGDLALARAATKAGIPFVLSTASNMSIEDLAR 120 Query: 121 AGPEALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKLP-- 178 L W QLY+ RE+ + +V +A GY + +T D G R D+ NRFK+P Sbjct: 121 QCDGDL-WFQLYVIH-REIAQGMVLKALHTGYTTLVLTTDVAVNGYRERDLHNRFKIPMS 178 Query: 179 ------------------------PQLRMKNF---ETSTLSFSPEENFGDDSGLAAYVAK 211 PQL NF +TS+L AA +++ Sbjct: 179 YSAKVVLDGCLHPRWSLDFVRHGMPQL--ANFVSSQTSSLEMQ-----------AALMSR 225 Query: 212 AIDPSISWEDIKWLRRLTSLPIVAKGILRGDDAREAVKHGLNGILVSNHGARQLDGVPAT 271 +D S +WE ++WLR L ++ KG+L +DA + G +G+++SNHG RQLD + Sbjct: 226 QMDASFNWEALRWLRDLWPHKLLVKGLLSAEDADRCIAEGADGVILSNHGGRQLDCAISP 285 Query: 272 IDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKGVQD 331 ++VL + V A GK V +D G R+G+D++KALALGA+AV +GR ++GLA +GE GV + Sbjct: 286 MEVLAQSV-AKTGK-PVLIDSGFRRGSDIVKALALGAEAVLLGRATLYGLAARGETGVDE 343 Query: 332 VLEILKEEFRLAMALSGCQNV 352 VL +LK + +A GC ++ Sbjct: 344 VLTLLKADIDRTLAQIGCPDI 364 >2J6X-A nrPDB Length = 374 Score = 212 bits (540), Expect = 2e-55, Method: Compositional matrix adjust. Identities = 123/362 (33%), Positives = 188/362 (51%), Gaps = 13/362 (3%) Query: 5 LICINDYEQHAKSVLPKSIYDYYRSGANDEETLADNIAAFSRWKLYPRMLRNVAETDLST 64 ++ D E+ A V+P ++Y + DE T N A+ LYPR+ ++V D ST Sbjct: 19 VVNTYDLEEEASKVVPHGGFNYIAGASGDEWTKRANDRAWKHKLLYPRLAQDVEAPDTST 78 Query: 65 SVLGQRVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSWATSSIEEVAEAGPE 124 +LG ++ P + A +AH E T RA GT M +S+++ ++ EE++E Sbjct: 79 EILGHKIKAPFIMAPIAAHGLAHTTKEAGTARAVSEFGTIMSISAYSGATFEEISEGLNG 138 Query: 125 ALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKLPPQLRM- 183 RW Q+Y+ KD + + ++ +A+ G AI +T D+ GNR DV+N+F P + + Sbjct: 139 GPRWFQIYMAKDDQQNRDILDEAKSDGATAIILTADSTVSGNRDRDVKNKFVYPFGMPIV 198 Query: 184 -KNFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVAKGILRGD 242 + + S +G A IS DI+ + + LP+ KGI + Sbjct: 199 QRYLRGTAEGMSLNNIYG-----------ASKQKISPRDIEEIAAHSGLPVFVKGIQHPE 247 Query: 243 DAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLK 302 DA A+K G +GI VSNHGARQL P + D LP I E V +V + D GVR+G V K Sbjct: 248 DADMAIKAGASGIWVSNHGARQLYEAPGSFDTLPAIAERVNKRVPIVFDSGVRRGEHVAK 307 Query: 303 ALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDKTLVRK 362 ALA GA V +GRP+++GLA G +G VL+ +++ M L+G QNV+ + + Sbjct: 308 ALASGADVVALGRPVLFGLALGGWQGAYSVLDYFQKDLTRVMQLTGSQNVEDLKGLDLFD 367 Query: 363 NP 364 NP Sbjct: 368 NP 369 >2CDH-0 nrPDB Length = 226 Score = 178 bits (452), Expect = 3e-45, Method: Compositional matrix adjust. Identities = 84/138 (60%), Positives = 112/138 (81%), Gaps = 1/138 (0%) Query: 211 KAIDPSISWEDIKWLRRLTSLPIVAKGILRGDDAREAVKHGLNGILVSNHGARQLDGVPA 270 KAI ++ W+D+ WL+ +TSLPI+ KG++ +DAR AV+HG GI+VSNHGARQLD VPA Sbjct: 90 KAIALTV-WKDVAWLQTITSLPILVKGVITAEDARLAVQHGAAGIIVSNHGARQLDYVPA 148 Query: 271 TIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKGVQ 330 TI L E+V+A +G++ VFLDGGVR+GTDV KALALGA VF+GRP+V+ LA +GE GV+ Sbjct: 149 TIMALEEVVKAAQGRIPVFLDGGVRRGTDVFKALALGAAGVFIGRPVVFSLAAEGEAGVK 208 Query: 331 DVLEILKEEFRLAMALSG 348 VL+++++EF L MALSG Sbjct: 209 KVLQMMRDEFELTMALSG 226 Score = 110 bits (275), Expect = 9e-25, Method: Compositional matrix adjust. Identities = 57/97 (58%), Positives = 75/97 (77%), Gaps = 1/97 (1%) Query: 63 STSVLGQRVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSWATSSIEEVAEAG 122 +T++LG ++SMPI + TAMQ+MAH +GE AT RA + GT M LSSWATSS+EEVA G Sbjct: 1 TTTILGFKISMPIMIAPTAMQKMAHPEGEYATARAASAAGTIMTLSSWATSSVEEVASTG 60 Query: 123 PEALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTV 159 P +R+ QLY+YKDR V +LVR+AE+ G+KAI +TV Sbjct: 61 P-GIRFFQLYVYKDRNVVAQLVRRAERAGFKAIALTV 96 >3SR7-A nrPDB Length = 365 Score = 47.8 bits (112), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 28/71 (39%), Positives = 40/71 (56%), Gaps = 6/71 (8%) Query: 285 KVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEIL---KEEFR 341 KVE+ GG+R D++KAL LGAKAV + R + L + V +V+ I+ KE+ R Sbjct: 278 KVEILASGGIRHPLDIIKALVLGAKAVGLSRTM---LELVEQHSVHEVIAIVNGWKEDLR 334 Query: 342 LAMALSGCQNV 352 L M CQ + Sbjct: 335 LIMCALNCQTI 345 >5LSM-A nrPDB Length = 359 Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust. Identities = 33/105 (31%), Positives = 49/105 (46%), Gaps = 15/105 (14%) Query: 210 AKAIDPSISWEDIKWLRRLTSLPIVAKGILRGDDAREAVKHGLNGILVSNHGARQLDGVP 269 +K I + + E+ WL + I+A+G+ G G G +S QL Sbjct: 149 SKVISTATTVEEALWLEARGADAIIAQGLEAG---------GHRGHFLSEDLTEQL---- 195 Query: 270 ATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVG 314 T +LP+I+ AVE + V GG+ T V A+ +GA AV VG Sbjct: 196 GTFSLLPQIIAAVE--IPVIAAGGIVDATTVRAAMTMGASAVQVG 238 >2ZRW-A nrPDB Length = 368 Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust. Identities = 22/69 (31%), Positives = 39/69 (56%), Gaps = 1/69 (1%) Query: 292 GGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQN 351 GG+R G D KA+ALGA + P++ A +G++ ++ + E + AM L+G ++ Sbjct: 274 GGIRSGLDAAKAIALGADIAGMALPVLKS-AIEGKESLEQFFRKIIFELKAAMMLTGSKD 332 Query: 352 VKVIDKTLV 360 V + KT + Sbjct: 333 VDALKKTSI 341 >4N02-A nrPDB Length = 357 Score = 38.9 bits (89), Expect = 0.004, Method: Compositional matrix adjust. Identities = 23/73 (31%), Positives = 38/73 (52%) Query: 285 KVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAM 344 KVE+ + GGVR D++K L GAKAV + R ++ + + V +++ K + RL M Sbjct: 266 KVELLVSGGVRNPLDMIKCLVFGAKAVGLSRTVLELVETYTVEEVIGIVQGWKADLRLIM 325 Query: 345 ALSGCQNVKVIDK 357 C + + K Sbjct: 326 CSLNCATIADLQK 338 >1P0K-A nrPDB Length = 349 Score = 38.9 bits (89), Expect = 0.004, Method: Compositional matrix adjust. Identities = 20/67 (29%), Positives = 37/67 (55%) Query: 291 DGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQ 350 GG++ DV KA+ALGA + + L GE+G+ + ++++ EE +L M + G + Sbjct: 257 SGGLQDALDVAKAIALGASCTGMAGHFLKALTDSGEEGLLEEIQLILEELKLIMTVLGAR 316 Query: 351 NVKVIDK 357 + + K Sbjct: 317 TIADLQK 323 >3FFS-A nrPDB Length = 400 Score = 34.7 bits (78), Expect = 0.068, Method: Compositional matrix adjust. Identities = 29/113 (25%), Positives = 54/113 (47%), Gaps = 7/113 (6%) Query: 222 IKWLRRLTSLPIVAKGILRGDDAREAVKHGLNGILV-----SNHGARQLDGVPATIDVLP 276 +K ++ ++ ++ ++ + +E +++G +GI V S R + GV Sbjct: 176 LKEIKSKMNIDVIVGNVVTEEATKELIENGADGIKVGIGPGSICTTRIVAGVGVPQITAI 235 Query: 277 EIVEAVEGK--VEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEK 327 E +V K + + DGG+R D+ KALA+GA +V +G + GEK Sbjct: 236 EKCSSVASKFGIPIIADGGIRYSGDIGKALAVGASSVMIGSILAGTEESPGEK 288 >5UQG-A nrPDB Length = 406 Score = 34.7 bits (78), Expect = 0.076, Method: Compositional matrix adjust. Identities = 22/49 (44%), Positives = 30/49 (61%), Gaps = 2/49 (4%) Query: 267 GVPATIDVLPEIVE-AVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVG 314 GVP I + E VE A + V V DGG++ D+ KALA+GA +V +G Sbjct: 231 GVP-QISAIDECVEEANKFGVPVIADGGIKYSGDIAKALAVGASSVMIG 278 >1VRD-A nrPDB Length = 494 Score = 34.3 bits (77), Expect = 0.092, Method: Compositional matrix adjust. Identities = 15/29 (51%), Positives = 21/29 (72%) Query: 286 VEVFLDGGVRKGTDVLKALALGAKAVFVG 314 V + DGG+R D++KALA GA++V VG Sbjct: 341 VPIIADGGIRYSGDIVKALAAGAESVMVG 369 >1EEP-A nrPDB Length = 404 Score = 33.9 bits (76), Expect = 0.10, Method: Compositional matrix adjust. Identities = 19/50 (38%), Positives = 29/50 (58%), Gaps = 2/50 (4%) Query: 267 GVPATIDVLPEIVEAVEG-KVEVFLDGGVRKGTDVLKALALGAKAVFVGR 315 GVP I + ++ EA + + DGG+R DV+KA+A GA +V +G Sbjct: 238 GVPQ-ITAICDVYEACNNTNICIIADGGIRFSGDVVKAIAAGADSVMIGN 286 >4QJ1-A nrPDB Length = 361 Score = 33.9 bits (76), Expect = 0.12, Method: Compositional matrix adjust. Identities = 29/113 (25%), Positives = 54/113 (47%), Gaps = 7/113 (6%) Query: 222 IKWLRRLTSLPIVAKGILRGDDAREAVKHGLNGILV-----SNHGARQLDGVPATIDVLP 276 +K ++ ++ ++ ++ + +E +++G +GI V S R + GV Sbjct: 137 LKEIKSKMNIDVIVGNVVTEEATKELIENGADGIKVGIGPGSICTTRIVAGVGVPQITAI 196 Query: 277 EIVEAVEGK--VEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEK 327 E +V K + + DGG+R D+ KALA+GA +V +G + GEK Sbjct: 197 EKCSSVASKFGIPIIADGGIRYSGDIGKALAVGASSVMIGSILAGTEESPGEK 249 >3TSB-A nrPDB Length = 511 Score = 33.5 bits (75), Expect = 0.15, Method: Compositional matrix adjust. Identities = 19/48 (39%), Positives = 26/48 (54%) Query: 267 GVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVG 314 GVP V EA + + V DGG++ D++KALA GA V +G Sbjct: 341 GVPQLTAVYDCATEARKHGIPVIADGGIKYSGDMVKALAAGAHVVMLG 388 >4MJM-A nrPDB Length = 385 Score = 33.5 bits (75), Expect = 0.17, Method: Compositional matrix adjust. Identities = 19/48 (39%), Positives = 26/48 (54%) Query: 267 GVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVG 314 GVP V EA + + V DGG++ D++KALA GA V +G Sbjct: 215 GVPQLTAVYDCATEARKHGIPVIADGGIKYSGDMVKALAAGAHVVMLG 262 >3R2G-A nrPDB Length = 361 Score = 32.7 bits (73), Expect = 0.24, Method: Compositional matrix adjust. Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 4/67 (5%) Query: 248 VKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALG 307 +K G+ G V + + GVP +L I + + DGG++ D++KALA G Sbjct: 166 IKAGIGGGSVCSTRIKTGFGVP----MLTCIQDCSRADRSIVADGGIKTSGDIVKALAFG 221 Query: 308 AKAVFVG 314 A V +G Sbjct: 222 ADFVMIG 228 >1XI3-A nrPDB Length = 215 Score = 32.7 bits (73), Expect = 0.27, Method: Compositional matrix adjust. Identities = 24/74 (32%), Positives = 42/74 (56%), Gaps = 9/74 (12%) Query: 193 FSPEENFGDDSGLAAYV-AKAIDPSISWED-----IKWLRRLTS---LPIVAKGILRGDD 243 +S EE + A Y+ A ++ P+ + ED ++ LR++ +P+VA G + D+ Sbjct: 116 YSLEEALEAEKKGADYLGAGSVFPTKTKEDARVIGLEGLRKIVESVKIPVVAIGGINKDN 175 Query: 244 AREAVKHGLNGILV 257 ARE +K G++GI V Sbjct: 176 AREVLKTGVDGIAV 189 >4FEZ-A nrPDB Length = 388 Score = 32.0 bits (71), Expect = 0.40, Method: Compositional matrix adjust. Identities = 19/48 (39%), Positives = 24/48 (50%) Query: 267 GVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVG 314 GVP + A E + V DGG+R D+ KA+A GA V VG Sbjct: 215 GVPQITAIADAAGVANEYGIPVIADGGIRFSGDISKAIAAGASCVMVG 262 >2CU0-A nrPDB Length = 486 Score = 32.0 bits (71), Expect = 0.47, Method: Compositional matrix adjust. Identities = 20/48 (41%), Positives = 26/48 (54%) Query: 267 GVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVG 314 GVP V A E + V DGG+R D++KA+A GA AV +G Sbjct: 310 GVPQITAVAMVADRAQEYGLYVIADGGIRYSGDIVKAIAAGADAVMLG 357 >4FXS-A nrPDB Length = 496 Score = 32.0 bits (71), Expect = 0.49, Method: Compositional matrix adjust. Identities = 19/48 (39%), Positives = 24/48 (50%) Query: 267 GVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVG 314 GVP + A E + V DGG+R D+ KA+A GA V VG Sbjct: 316 GVPQITAIADAAGVANEYGIPVIADGGIRFSGDISKAIAAGASCVMVG 363 >1WNF-A nrPDB Length = 328 Score = 31.6 bits (70), Expect = 0.60, Method: Compositional matrix adjust. Identities = 20/72 (27%), Positives = 39/72 (54%), Gaps = 5/72 (6%) Query: 219 WEDIKWLRRLTSLPIVAKGILRGDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEI 278 + DIK+ ++ + ++ L GD REA++ G GI++ +G + G+P L E+ Sbjct: 193 FSDIKYEPKVLVIKLIPG--LSGDIVREALRLGYKGIILEGYG---VGGIPYRGTDLFEV 247 Query: 279 VEAVEGKVEVFL 290 V ++ ++ V L Sbjct: 248 VSSISKRIPVVL 259 >2GGG-A nrPDB Length = 375 Score = 31.6 bits (70), Expect = 0.62, Method: Compositional matrix adjust. Identities = 30/132 (22%), Positives = 59/132 (44%), Gaps = 10/132 (7%) Query: 129 LQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKLPPQLRMKNFET 188 + L I D + T LVR+ + GY+ I + + G + VR + P +R+ Sbjct: 141 VSLGIQADEQATVDLVRRHVEQGYRRIKLKIKP---GWDVQPVRATREAFPDIRLTVDAN 197 Query: 189 STLSFSPEENFGDDSGLAAYVAKAIDPSISWEDI----KWLRRLTSLPIVAKGILRGDDA 244 S + + + G L Y I+ ++W+D+ + RR+ + + + + DA Sbjct: 198 SAYTLA---DAGRLRQLDEYDLTYIEQPLAWDDLVDHAELARRIRTPLCLDESVASASDA 254 Query: 245 REAVKHGLNGIL 256 R+A+ G G++ Sbjct: 255 RKALALGAGGVI 266 >1ZFJ-A nrPDB Length = 491 Score = 31.2 bits (69), Expect = 0.68, Method: Compositional matrix adjust. Identities = 17/48 (35%), Positives = 24/48 (50%) Query: 267 GVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVG 314 GVP + A E + DGG++ D++KALA G AV +G Sbjct: 318 GVPQVTAIYDAAAVAREYGKTIIADGGIKYSGDIVKALAAGGNAVMLG 365 >5ICQ-A nrPDB Length = 610 Score = 30.8 bits (68), Expect = 0.88, Method: Compositional matrix adjust. Identities = 31/125 (24%), Positives = 54/125 (43%), Gaps = 7/125 (5%) Query: 234 VAKGILRGDDAREA--VKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLD 291 +A G+++ A + V + L G+ G R+L + A + VLP+ VE + L Sbjct: 165 IAYGLVKSATAPDPHRVAYDLTGV-----GDRELPLILAIMPVLPKHALDVERFSDATLA 219 Query: 292 GGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQN 351 + G V+ + GA+ + P WG ++G + EI + FR +L Sbjct: 220 KPLGSGPYVVADVQAGARLLLKRDPNYWGADIPSQRGFYNFDEIDLQYFRDGNSLFEAFK 279 Query: 352 VKVID 356 +ID Sbjct: 280 AGLID 284 >5CSS-A nrPDB Length = 226 Score = 30.4 bits (67), Expect = 1.2, Method: Compositional matrix adjust. Identities = 14/47 (29%), Positives = 28/47 (59%), Gaps = 1/47 (2%) Query: 273 DVLPEIVEAVEGK-VEVFLDGGVRKGTDVLKALALGAKAVFVGRPIV 318 +++ +IV+ EG V + G++ G DV +++ LGA+ + V +V Sbjct: 156 EIIEDIVKIYEGTGTSVLVGAGIKTGEDVRRSIGLGARGILVASGVV 202 Score = 29.6 bits (65), Expect = 2.1, Method: Compositional matrix adjust. Identities = 21/84 (25%), Positives = 39/84 (46%), Gaps = 5/84 (5%) Query: 183 MKNFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVAKGILRGD 242 + +E +++ P + G D ++ AK P I + +K + +V GI G+ Sbjct: 128 FREYEPDFIAYEPRDLIGGD--VSVSTAK---PEIIEDIVKIYEGTGTSVLVGAGIKTGE 182 Query: 243 DAREAVKHGLNGILVSNHGARQLD 266 D R ++ G GILV++ + D Sbjct: 183 DVRRSIGLGARGILVASGVVKSAD 206 >5AHL-A nrPDB Length = 400 Score = 30.4 bits (67), Expect = 1.2, Method: Compositional matrix adjust. Identities = 19/49 (38%), Positives = 27/49 (55%), Gaps = 2/49 (4%) Query: 267 GVPATIDVLPEIVEAVEGK-VEVFLDGGVRKGTDVLKALALGAKAVFVG 314 GVP I + + A+EG V + DGG+R D+ KA+ GA V +G Sbjct: 224 GVP-QISAIANVAAALEGTGVPLIADGGIRFSGDLAKAMVAGAYCVMMG 271 >4DQW-A nrPDB Length = 509 Score = 30.0 bits (66), Expect = 1.6, Method: Compositional matrix adjust. Identities = 19/49 (38%), Positives = 27/49 (55%), Gaps = 2/49 (4%) Query: 267 GVPATIDVLPEIVEAVEGK-VEVFLDGGVRKGTDVLKALALGAKAVFVG 314 GVP I + + A+EG V + DGG+R D+ KA+ GA V +G Sbjct: 333 GVP-QISAIANVAAALEGTGVPLIADGGIRFSGDLAKAMVAGAYCVMMG 380 >2H6R-A nrPDB Length = 219 Score = 30.0 bits (66), Expect = 1.6, Method: Compositional matrix adjust. Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 8/59 (13%) Query: 267 GVPATIDVLPEIVEA-------VEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIV 318 G+P + PE+VE + V+V G+ KG DV AL LGA+ V + +V Sbjct: 146 GIPVS-KANPEVVEGTVRAVKEINKDVKVLCGAGISKGEDVKAALDLGAEGVLLASGVV 203 >6I0M-A nrPDB Length = 517 Score = 30.0 bits (66), Expect = 1.7, Method: Compositional matrix adjust. Identities = 24/78 (30%), Positives = 36/78 (46%), Gaps = 8/78 (10%) Query: 286 VEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMA 345 V V DGG++ + KALALGA V +G + GE D + + K +R Sbjct: 362 VPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKK--YR---- 415 Query: 346 LSGCQNVKVIDKTLVRKN 363 G ++ +DK L +N Sbjct: 416 --GMGSLDAMDKHLSSQN 431 >2IHN-A nrPDB Length = 305 Score = 30.0 bits (66), Expect = 1.7, Method: Compositional matrix adjust. Identities = 17/58 (29%), Positives = 31/58 (53%), Gaps = 4/58 (6%) Query: 133 IYKDREVTKKLVRQAEKMGYKAIFVTVDTPY----LGNRLDDVRNRFKLPPQLRMKNF 186 I DRE K L+ ++E YK V +D Y + + + + N +KLPP+ ++ ++ Sbjct: 232 IANDREQAKVLLTESEYNRYKENLVLIDFDYIPDNIASNIVNYYNSYKLPPRGKIYSY 289 >1UUO-A nrPDB Length = 372 Score = 29.6 bits (65), Expect = 2.0, Method: Compositional matrix adjust. Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 12/78 (15%) Query: 251 GLNGILVSNHGARQLDGVPA---TIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALG 307 GL G L S G L G P + + E+ +G++ + GGV G D L+ + G Sbjct: 268 GLQGALRSETGG--LSGKPLRDLSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAG 325 Query: 308 AKAV-------FVGRPIV 318 A V F+G P+V Sbjct: 326 ASLVQLYTALIFLGPPVV 343 >5UPU-A nrPDB Length = 407 Score = 29.3 bits (64), Expect = 2.5, Method: Compositional matrix adjust. Identities = 16/48 (33%), Positives = 22/48 (45%) Query: 267 GVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVG 314 G P +L + V V DGG++ D+ KALA GA +G Sbjct: 228 GAPQITAILEAVAACRPAGVPVIADGGLQYSGDIAKALAAGASTAMLG 275 >1JCN-A nrPDB Length = 514 Score = 29.3 bits (64), Expect = 2.5, Method: Compositional matrix adjust. Identities = 14/29 (48%), Positives = 19/29 (65%) Query: 286 VEVFLDGGVRKGTDVLKALALGAKAVFVG 314 V + DGG++ V+KALALGA V +G Sbjct: 359 VPIIADGGIQTVGHVVKALALGASTVMMG 387 >3N2S-A nrPDB Length = 249 Score = 29.3 bits (64), Expect = 2.6, Method: Compositional matrix adjust. Identities = 18/46 (39%), Positives = 23/46 (50%), Gaps = 4/46 (8%) Query: 13 QHAKSVLPKSIYDYYRSGAND--EETLADNIAAFSRWKLYPRMLRN 56 +H + K+I DYYR N EET +D I F + K PR N Sbjct: 195 RHTMNTYDKTISDYYRERTNGKREETWSDQILNFMKQK--PRTYLN 238 >1WNB-A nrPDB Length = 495 Score = 29.3 bits (64), Expect = 2.7, Method: Compositional matrix adjust. Identities = 17/30 (56%), Positives = 19/30 (63%) Query: 252 LNGILVSNHGARQLDGVPATIDVLPEIVEA 281 +NG LVS G +Q PAT DVL EI EA Sbjct: 28 INGELVSGEGEKQPVYNPATGDVLLEIAEA 57 >1IUQ-A nrPDB Length = 367 Score = 29.3 bits (64), Expect = 2.7, Method: Compositional matrix adjust. Identities = 19/71 (26%), Positives = 32/71 (45%), Gaps = 3/71 (4%) Query: 243 DAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLK 302 D E ++ G N +L+SNH Q + PA I +L E + +F+ G + K Sbjct: 121 DIEEKLQQGHNVVLISNH---QTEADPAIISLLLEKTNPYIAENTIFVAGDRVLADPLCK 177 Query: 303 ALALGAKAVFV 313 ++G + V Sbjct: 178 PFSIGRNLICV 188 >4TWE-A nrPDB Length = 743 Score = 28.9 bits (63), Expect = 3.8, Method: Compositional matrix adjust. Identities = 15/40 (37%), Positives = 21/40 (52%) Query: 237 GILRGDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLP 276 G+ RG A A KHG+ G+LV A DG+ + + P Sbjct: 198 GVGRGAKAVNAAKHGVAGVLVYTDPADINDGLSSPDETFP 237 >1TJR-A nrPDB Length = 261 Score = 28.9 bits (63), Expect = 4.1, Method: Compositional matrix adjust. Identities = 39/190 (20%), Positives = 80/190 (42%), Gaps = 22/190 (11%) Query: 87 HVDGELATVRACQSLGTGMMLSSWATSSIEEVAEAGPEALRWLQLYIYKDREVTKKLVRQ 146 ++DG + ++L +G + + +E + E PE + L Y +++ L Sbjct: 58 YIDGPIIQASVARALASGTTMDAV----LEMLREVTPELSCPVVLLSYYKPIMSRSLAEM 113 Query: 147 AEKMGYKAIFVTVDTPYLG----------NRLDDVRNRFKLPPQLRMKNFETSTLSFSPE 196 E G + V D PY+ N L+ V P+ RMK ++ F Sbjct: 114 KEA-GVHGLIVP-DLPYVAAHSLWSEAKNNNLELVLLTTPAIPEDRMKEITKASEGFVYL 171 Query: 197 ENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPI-VAKGILRGDDAREAVKHGLNGI 255 + +G A V ++ I+ ++++T+ P+ V GI + + ++ + G +G+ Sbjct: 172 VSVNGVTGPRANVNPRVE-----SLIQEVKKVTNKPVAVGFGISKPEHVKQIAQWGADGV 226 Query: 256 LVSNHGARQL 265 ++ + RQL Sbjct: 227 IIGSAMVRQL 236 >5Z9Y-A nrPDB Length = 252 Score = 28.5 bits (62), Expect = 4.3, Method: Compositional matrix adjust. Identities = 17/58 (29%), Positives = 27/58 (46%), Gaps = 7/58 (12%) Query: 128 WLQLYIYKDREV----TKKLVRQAEKM---GYKAIFVTVDTPYLGNRLDDVRNRFKLP 178 W++L + D +LVR AE++ G+ + T D P L RL+D +P Sbjct: 96 WVKLEVIADERTLWPDAVELVRAAEQLVDDGFVVLPYTTDDPVLARRLEDTGCAAVMP 153 >6C43-A nrPDB Length = 477 Score = 28.5 bits (62), Expect = 4.5, Method: Compositional matrix adjust. Identities = 15/30 (50%), Positives = 19/30 (63%) Query: 252 LNGILVSNHGARQLDGVPATIDVLPEIVEA 281 +NG+LV G RQ PAT +V+ EI EA Sbjct: 10 INGVLVDGEGERQSVYNPATGEVILEIAEA 39 >4XTI-A nrPDB Length = 413 Score = 28.5 bits (62), Expect = 5.4, Method: Compositional matrix adjust. Identities = 26/101 (25%), Positives = 44/101 (43%), Gaps = 8/101 (7%) Query: 222 IKWLRR-LTSLPIVAKGILRGDDAREAVKHGLNGILVS-NHGARQLD------GVPATID 273 IKW++ L ++A ++ + A + G +G+ + G+ + G P Sbjct: 181 IKWIKETFPDLQVIAGNVVTREQAASLIHAGADGLRIGMGSGSICITQEVMACGRPQGTA 240 Query: 274 VLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVG 314 V A + V DGGV+ + KA+ALGA V +G Sbjct: 241 VYNVTQFANQFGVPCIADGGVQNIGHITKAIALGASTVMMG 281 >4Z87-A nrPDB Length = 525 Score = 28.1 bits (61), Expect = 5.9, Method: Compositional matrix adjust. Identities = 26/101 (25%), Positives = 44/101 (43%), Gaps = 8/101 (7%) Query: 222 IKWLRR-LTSLPIVAKGILRGDDAREAVKHGLNGILVS-NHGARQLD------GVPATID 273 IKW++ L ++A ++ + A + G +G+ + G+ + G P Sbjct: 293 IKWIKETFPDLQVIAGNVVTREQAASLIHAGADGLRIGMGSGSICITQEVMACGRPQGTA 352 Query: 274 VLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVG 314 V A + V DGGV+ + KA+ALGA V +G Sbjct: 353 VYNVTQFANQFGVPCIADGGVQNIGHITKAIALGASTVMMG 393 >1YPF-A nrPDB Length = 336 Score = 28.1 bits (61), Expect = 6.2, Method: Compositional matrix adjust. Identities = 11/27 (40%), Positives = 16/27 (59%) Query: 288 VFLDGGVRKGTDVLKALALGAKAVFVG 314 + DGG+R DV K++ GA V +G Sbjct: 213 IIADGGIRTNGDVAKSIRFGATMVMIG 239 >1U7N-A nrPDB Length = 336 Score = 28.1 bits (61), Expect = 6.3, Method: Compositional matrix adjust. Identities = 19/50 (38%), Positives = 24/50 (48%), Gaps = 9/50 (18%) Query: 247 AVKHGLNGILVSNHGARQLDGVPATI---------DVLPEIVEAVEGKVE 287 AV GL ++ HGA D V TI V+P++VE EGK E Sbjct: 287 AVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETQVVPQLVEYYEGKAE 336 >3U2O-A nrPDB Length = 395 Score = 28.1 bits (61), Expect = 6.6, Method: Compositional matrix adjust. Identities = 31/101 (30%), Positives = 41/101 (40%), Gaps = 20/101 (19%) Query: 251 GLNGILVSNHGARQLDGVPA---TIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALG 307 GL G L S G L G P + + E+ +G+V + GGV G D L+ + G Sbjct: 291 GLQGALRSETGG--LSGKPLRDLSTQTIREMYALTQGRVPIIGVGGVSSGQDALEKIRAG 348 Query: 308 AKAV-------FVGRPIVWG--------LAFQGEKGVQDVL 333 A V F G P+V L QG GV D + Sbjct: 349 ASLVQLYTALTFWGPPVVGKVKRELEALLKEQGFGGVTDAI 389 >4JDY-A nrPDB Length = 264 Score = 27.7 bits (60), Expect = 9.4, Method: Compositional matrix adjust. Identities = 16/48 (33%), Positives = 25/48 (52%) Query: 270 ATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPI 317 A +++ E+ A + V +F GG+ D + LGA+ VFVG I Sbjct: 186 APYELVAEVARAGKLPVTLFTAGGIATPADAAMMMQLGAEGVFVGSGI 233 >4AF0-B nrPDB Length = 556 Score = 27.3 bits (59), Expect = 9.9, Method: Compositional matrix adjust. Identities = 26/103 (25%), Positives = 46/103 (44%), Gaps = 8/103 (7%) Query: 220 EDIKWLRR-LTSLPIVAKGILRGDDAREAVKHGLNGILVS-NHGARQLD------GVPAT 271 E IKW+++ + ++A ++ + A + + G +G+ + G+ + G P Sbjct: 311 EFIKWIKQTYPKIDVIAGNVVTREQAAQLIAAGADGLRIGMGSGSICITQEVMAVGRPQG 370 Query: 272 IDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVG 314 V A + DGG+ + KALALGA AV +G Sbjct: 371 TAVYAVAEFASRFGIPCIADGGIGNIGHIAKALALGASAVMMG 413 >1HG3-A nrPDB Length = 225 Score = 27.3 bits (59), Expect = 10.0, Method: Compositional matrix adjust. Identities = 16/46 (34%), Positives = 23/46 (50%) Query: 269 PATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVG 314 P I E+V+ V +V+V G+ G DV KA+ LG V + Sbjct: 160 PEVITNTVELVKKVNPEVKVLCGAGISTGEDVKKAIELGTVGVLLA 205 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2RDU-A nrPDB 529 e-151 1AL8-A nrPDB 488 e-138 5ZBN-A nrPDB 483 e-137 3SGZ-A nrPDB 451 e-127 1SZG-A nrPDB 443 e-125 1QCW-A nrPDB 441 e-124 2A85-A nrPDB 438 e-123 2J6X-A nrPDB 433 e-122 6DVI-A nrPDB 428 e-120 6BFG-A nrPDB 404 e-113 2CDH-0 nrPDB 254 4e-68 5LSM-A nrPDB 94 7e-20 3SR7-A nrPDB 90 1e-18 2ZRW-A nrPDB 81 7e-16 Sequences not found previously or not previously below threshold: 4N02-A nrPDB 84 1e-16 1P0K-A nrPDB 78 7e-15 4Q4K-A nrPDB 59 3e-09 3FFS-A nrPDB 49 3e-06 4QJ1-A nrPDB 49 4e-06 1VRD-A nrPDB 49 4e-06 4Z87-A nrPDB 47 1e-05 4XTI-A nrPDB 46 3e-05 3DH7-A nrPDB 46 3e-05 4FXS-A nrPDB 46 3e-05 4FEZ-A nrPDB 46 4e-05 4MJM-A nrPDB 46 4e-05 2GJN-A nrPDB 45 5e-05 1JCN-A nrPDB 43 2e-04 6I0M-A nrPDB 43 2e-04 4AF0-B nrPDB 43 3e-04 4DQW-A nrPDB 42 3e-04 3TSB-A nrPDB 42 3e-04 5AHL-A nrPDB 42 4e-04 3BW4-A nrPDB 42 5e-04 5UQG-A nrPDB 42 6e-04 2Z6J-A nrPDB 41 7e-04 1ZFJ-A nrPDB 41 0.001 1TV5-A nrPDB 40 0.001 5UPU-A nrPDB 40 0.002 6I4B-A nrPDB 40 0.002 3OIX-A nrPDB 39 0.003 2CU0-A nrPDB 38 0.005 1TYG-A nrPDB 38 0.005 4JDY-A nrPDB 38 0.006 3U2O-A nrPDB 38 0.007 4IQL-A nrPDB 38 0.007 1JUE-A nrPDB 38 0.008 1YPF-A nrPDB 38 0.008 2H6R-A nrPDB 37 0.009 1EEP-A nrPDB 37 0.010 1UUO-A nrPDB 37 0.013 5CSS-A nrPDB 36 0.025 3R2G-A nrPDB 35 0.033 4WY0-A nrPDB 35 0.039 2ISS-A nrPDB 35 0.043 2NV2-A nrPDB 35 0.053 1VHN-A nrPDB 35 0.069 2GGG-A nrPDB 34 0.075 5Z9Y-A nrPDB 34 0.084 1WX0-A nrPDB 34 0.11 1TJR-A nrPDB 34 0.11 3W7D-A nrPDB 34 0.12 4UTT-A nrPDB 34 0.12 4N6F-A nrPDB 34 0.14 1AK5-A nrPDB 34 0.14 6B8S-A nrPDB 34 0.15 3T55-A nrPDB 33 0.21 1WV2-A nrPDB 33 0.23 2IHN-A nrPDB 33 0.23 1HG3-A nrPDB 33 0.23 4WZH-A nrPDB 32 0.28 2C6Q-A nrPDB 32 0.33 4ADT-A nrPDB 32 0.38 2YZR-A nrPDB 32 0.39 2Y88-A nrPDB 32 0.42 4FIQ-A nrPDB 32 0.43 1B0U-A nrPDB 32 0.45 1MZH-A nrPDB 32 0.50 1UB3-A nrPDB 32 0.50 6MFM-A nrPDB 32 0.58 5XFW-A nrPDB 32 0.61 5ZKN-A nrPDB 31 0.64 5UE9-A nrPDB 31 0.88 2BWG-A nrPDB 31 0.92 3GZ3-A nrPDB 31 0.96 1XI3-A nrPDB 30 1.2 3L5A-A nrPDB 30 1.2 1N7K-A nrPDB 30 1.2 2ZBT-A nrPDB 30 1.4 1YQX-A nrPDB 30 1.4 1OI7-A nrPDB 30 1.5 3THA-A nrPDB 30 1.7 1F76-A nrPDB 30 1.8 5K8C-A nrPDB 30 2.1 2VEP-A nrPDB 30 2.4 4JEJ-A nrPDB 29 2.7 1H5Y-A nrPDB 29 2.7 4MM1-A nrPDB 29 3.0 1KA9-F nrPDB 29 3.3 5G1T-A nrPDB 29 3.6 3PB0-A nrPDB 29 3.6 4AXK-A nrPDB 29 3.6 4X2R-A nrPDB 29 4.1 6NKE-A nrPDB 29 4.2 2JS7-A nrPDB 29 4.2 1P9H-A nrPDB 28 6.0 4WQ4-C nrPDB 28 7.2 2XZ9-A nrPDB 28 7.6 >2RDU-A nrPDB Length = 387 Score = 529 bits (1363), Expect = e-151, Method: Composition-based stats. Identities = 370/370 (100%), Positives = 370/370 (100%) Query: 1 MLPRLICINDYEQHAKSVLPKSIYDYYRSGANDEETLADNIAAFSRWKLYPRMLRNVAET 60 MLPRLICINDYEQHAKSVLPKSIYDYYRSGANDEETLADNIAAFSRWKLYPRMLRNVAET Sbjct: 18 MLPRLICINDYEQHAKSVLPKSIYDYYRSGANDEETLADNIAAFSRWKLYPRMLRNVAET 77 Query: 61 DLSTSVLGQRVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSWATSSIEEVAE 120 DLSTSVLGQRVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSWATSSIEEVAE Sbjct: 78 DLSTSVLGQRVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSWATSSIEEVAE 137 Query: 121 AGPEALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKLPPQ 180 AGPEALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKLPPQ Sbjct: 138 AGPEALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKLPPQ 197 Query: 181 LRMKNFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVAKGILR 240 LRMKNFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVAKGILR Sbjct: 198 LRMKNFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVAKGILR 257 Query: 241 GDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDV 300 GDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDV Sbjct: 258 GDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDV 317 Query: 301 LKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDKTLV 360 LKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDKTLV Sbjct: 318 LKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDKTLV 377 Query: 361 RKNPLAVSKI 370 RKNPLAVSKI Sbjct: 378 RKNPLAVSKI 387 >1AL8-A nrPDB Length = 359 Score = 488 bits (1255), Expect = e-138, Method: Composition-based stats. Identities = 201/356 (56%), Positives = 267/356 (75%), Gaps = 4/356 (1%) Query: 5 LICINDYEQHAKSVLPKSIYDYYRSGANDEETLADNIAAFSRWKLYPRMLRNVAETDLST 64 + +N+YE AK LPK +YDYY SGA D+ TLA+N AFSR PR+L +V D++T Sbjct: 3 ITNVNEYEAIAKQKLPKMVYDYYASGAEDQWTLAENRNAFSRILFRPRILIDVTNIDMTT 62 Query: 65 SVLGQRVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSWATSSIEEVAEAGPE 124 ++LG ++SMPI + TAMQ+MAH +GE AT RA + GT M LSSWATSS+EEVA GP Sbjct: 63 TILGFKISMPIMIAPTAMQKMAHPEGEYATARAASAAGTIMTLSSWATSSVEEVASTGP- 121 Query: 125 ALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKLPPQLRMK 184 +R+ QLY+YKDR V +LVR+AE+ G+KAI +TVDTP LG R D++NRF LPP L +K Sbjct: 122 GIRFFQLYVYKDRNVVAQLVRRAERAGFKAIALTVDTPRLGRREADIKNRFVLPPFLTLK 181 Query: 185 NFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVAKGILRGDDA 244 NFE L + N DSGL++YVA ID S+SW+D+ WL+ +TSLPI+ KG++ +DA Sbjct: 182 NFEGIDLGKMDKAN---DSGLSSYVAGQIDRSLSWKDVAWLQTITSLPILVKGVITAEDA 238 Query: 245 REAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKAL 304 R AV+HG GI+VSNHGARQLD VPATI L E+V+A +G++ VFLDGGVR+GTDV KAL Sbjct: 239 RLAVQHGAAGIIVSNHGARQLDYVPATIMALEEVVKAAQGRIPVFLDGGVRRGTDVFKAL 298 Query: 305 ALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDKTLV 360 ALGA VF+GRP+V+ LA +GE GV+ VL+++++EF L MALSGC+++K I ++ + Sbjct: 299 ALGAAGVFIGRPVVFSLAAEGEAGVKKVLQMMRDEFELTMALSGCRSLKEISRSHI 354 >5ZBN-A nrPDB Length = 371 Score = 483 bits (1243), Expect = e-137, Method: Composition-based stats. Identities = 197/359 (54%), Positives = 266/359 (74%), Gaps = 4/359 (1%) Query: 2 LPRLICINDYEQHAKSVLPKSIYDYYRSGANDEETLADNIAAFSRWKLYPRMLRNVAETD 61 + + + +YE AK LPK ++DYY SGA D+ TLA+N AFSR PR+L +V++ D Sbjct: 1 MEEVTNVMEYEAIAKKKLPKMVFDYYASGAEDQWTLAENRNAFSRILFRPRILIDVSKID 60 Query: 62 LSTSVLGQRVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSWATSSIEEVAEA 121 +ST+VLG ++SMPI + TAMQ+MAH +GE AT RA + GT M LSSWATSS+EEVA Sbjct: 61 MSTTVLGFKISMPIMIAPTAMQKMAHPEGEYATARAASAAGTIMTLSSWATSSVEEVAST 120 Query: 122 GPEALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKLPPQL 181 GP +R+ QLY+YKDR V +LVR+AE+ G+KAI +TVDTP LG R D++NRF LPP L Sbjct: 121 GP-GIRFFQLYVYKDRNVVAQLVRRAERAGFKAIALTVDTPRLGRREADIKNRFVLPPFL 179 Query: 182 RMKNFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVAKGILRG 241 +KNFE L + DSGLA+YVA ID ++SW+D++WL+ +TSLPI+ KG+L Sbjct: 180 TLKNFEGLDLGKMDQA---SDSGLASYVAGQIDRTLSWKDVQWLQTITSLPILVKGVLTA 236 Query: 242 DDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVL 301 +DAR AV+ G GI+VSNHGARQLD VP+TI L E+V+A +G++ VFLDGGVR+GTDV Sbjct: 237 EDARLAVQAGAAGIIVSNHGARQLDYVPSTIMALEEVVKAAQGRIPVFLDGGVRRGTDVF 296 Query: 302 KALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDKTLV 360 KALALGA +F+GRP+V+ LA +GE G++ VL++L++EF L MALSGC+++ I + + Sbjct: 297 KALALGASGIFIGRPVVFSLAAEGEAGIKKVLQMLRDEFELTMALSGCRSLNEITRNHI 355 >3SGZ-A nrPDB Length = 352 Score = 451 bits (1160), Expect = e-127, Method: Composition-based stats. Identities = 164/357 (45%), Positives = 232/357 (64%), Gaps = 10/357 (2%) Query: 5 LICINDYEQHAKSVLPKSIYDYYRSGANDEETLADNIAAFSRWKLYPRMLRNVAETDLST 64 L+C+ D++ HA+ L K+ +D+ A+D T ++NIAAF R +L PR LR++++ D T Sbjct: 2 LVCLADFKAHAQKQLSKTSWDFIEGEADDGITYSENIAAFKRIRLRPRYLRDMSKVDTRT 61 Query: 65 SVLGQRVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSWATSSIEEVAEAGPE 124 ++ GQ +S PIC+ TA +A DGE +T RA Q ++SS+A+ S+E++ A PE Sbjct: 62 TIQGQEISAPICISPTAFHSIAWPDGEKSTARAAQEANICYVISSYASYSLEDIVAAAPE 121 Query: 125 ALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKLPPQLRMK 184 RW QLY+ D + K++V++AE +G+KA+ +T+DTP LGNR D RN+ L Sbjct: 122 GFRWFQLYMKSDWDFNKQMVQRAEALGFKALVITIDTPVLGNRRRDKRNQLNLEA----- 176 Query: 185 NFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVAKGILRGDDA 244 N + L EE + KA S W D+ L+ +T LPI+ KGIL +DA Sbjct: 177 NILKAALRALKEEK--PTQSVPVLFPKA---SFCWNDLSLLQSITRLPIILKGILTKEDA 231 Query: 245 REAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKAL 304 A+KH + GI+VSNHG RQLD V A+ID L E+V AV+GK+EV++DGGVR GTDVLKAL Sbjct: 232 ELAMKHNVQGIVVSNHGGRQLDEVSASIDALREVVAAVKGKIEVYMDGGVRTGTDVLKAL 291 Query: 305 ALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDKTLVR 361 ALGA+ +F+GRPI+WGLA +GE GV++VL+IL E M LSGCQ+V I L++ Sbjct: 292 ALGARCIFLGRPILWGLACKGEDGVKEVLDILTAELHRCMTLSGCQSVAEISPDLIQ 348 >1SZG-A nrPDB Length = 511 Score = 443 bits (1138), Expect = e-125, Method: Composition-based stats. Identities = 143/369 (38%), Positives = 219/369 (59%), Gaps = 19/369 (5%) Query: 2 LPRLICINDYEQHAKSVLPKSIYDYYRSGANDEETLADNIAAFSRWKLYPRMLRNVAETD 61 L +I + D+E A L K + YY SGANDE T +N A+ R P++L +V + D Sbjct: 119 LDNIINLYDFEYLASQTLTKQAWAYYSSGANDEVTHRENHNAYHRIFFKPKILVDVRKVD 178 Query: 62 LSTSVLGQRVSMPICVGATAMQRMAHV-DGELATVRACQS--LGTGMMLSSWATSSIEEV 118 +ST +LG V +P V AT + ++ + +GE R C M+S+ A+ S EE+ Sbjct: 179 ISTDMLGSHVDVPFYVSATGLCKLGNPLEGEKDVARGCGQGVTKVPQMISTAASCSPEEI 238 Query: 119 AEAGP--EALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFK 176 EA P + ++W QLY+ DR++T LV+ EK+G KA+FVTVD P LG R D++ +F Sbjct: 239 IEAAPSDKQIQWYQLYVNSDRKITDDLVKNVEKLGVKALFVTVDAPSLGQREKDMKLKF- 297 Query: 177 LPPQLRMKNFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVAK 236 + + + N + G + ++K IDPS++W+DI+ L++ T LPIV K Sbjct: 298 --------SNTKAGPKAMKKTNVEESQGASRALSKFIDPSLTWKDIEELKKKTKLPIVIK 349 Query: 237 GILRGDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVE-----GKVEVFLD 291 G+ R +D +A + G++G+++SNHG RQLD A I+VL E + +E K+EVF+D Sbjct: 350 GVQRTEDVIKAAEIGVSGVVLSNHGGRQLDFSRAPIEVLAETMPILEQRNLKDKLEVFVD 409 Query: 292 GGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQN 351 GGVR+GTDVLKAL LGAK V +GRP ++ + G GV+ +EIL++E ++M L G + Sbjct: 410 GGVRRGTDVLKALCLGAKGVGLGRPFLYANSCYGRNGVEKAIEILRDEIEMSMRLLGVTS 469 Query: 352 VKVIDKTLV 360 + + L+ Sbjct: 470 IAELKPDLL 478 >1QCW-A nrPDB Length = 410 Score = 441 bits (1135), Expect = e-124, Method: Composition-based stats. Identities = 143/369 (38%), Positives = 220/369 (59%), Gaps = 19/369 (5%) Query: 2 LPRLICINDYEQHAKSVLPKSIYDYYRSGANDEETLADNIAAFSRWKLYPRMLRNVAETD 61 L +I + D+E A L K + YY SGANDE T +N A+ R P++L +V + D Sbjct: 18 LDNIINLYDFEYLASQTLTKQAWAYYSSGANDEVTHRENHNAYHRIFFKPKILVDVRKVD 77 Query: 62 LSTSVLGQRVSMPICVGATAMQRMAHV-DGELATVRACQS--LGTGMMLSSWATSSIEEV 118 +ST +LG V +P V ATA+ ++ + +GE R C M+S+ A+ S EE+ Sbjct: 78 ISTDMLGSHVDVPFYVSATALCKLGNPLEGEKDVARGCGQGVTKVPQMISTLASCSPEEI 137 Query: 119 AEAGP--EALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFK 176 EA P + ++W QLY+ DR++T LV+ EK+G KA+FVTVD P LG + D++ +F Sbjct: 138 IEAAPSDKQIQWYQLYVNSDRKITDDLVKNVEKLGVKALFVTVDAPSLGQKEKDMKLKF- 196 Query: 177 LPPQLRMKNFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVAK 236 + + + N + G + ++K IDPS++W+DI+ L++ T LPIV K Sbjct: 197 --------SNTKAGFKAMKKTNVEESQGASRALSKFIDPSLTWKDIEELKKKTKLPIVIK 248 Query: 237 GILRGDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVE-----GKVEVFLD 291 G+ R +D +A + G++G+++SNHG RQLD A I+VL E + +E K+EVF+D Sbjct: 249 GVQRTEDVIKAAEIGVSGVVLSNHGGRQLDFSRAPIEVLAETMPILEQRNLKDKLEVFVD 308 Query: 292 GGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQN 351 GGVR+GTDVLKAL LGAK V +GRP ++ + G GV+ +EIL++E ++M L G + Sbjct: 309 GGVRRGTDVLKALCLGAKGVGLGRPFLYANSCYGRNGVEKAIEILRDEIEMSMRLLGVTS 368 Query: 352 VKVIDKTLV 360 + + L+ Sbjct: 369 IAELKPDLL 377 >2A85-A nrPDB Length = 380 Score = 438 bits (1126), Expect = e-123, Method: Composition-based stats. Identities = 135/362 (37%), Positives = 205/362 (56%), Gaps = 7/362 (1%) Query: 1 MLPRLICINDYEQHAKSVLPKSIYDYYRSGANDEETLADNIAAFSRWKLYPRMLRNVAET 60 M L + DY + A+ LPK +YDY GA DE + N F +W+ P+ L +V+ Sbjct: 1 MSQNLFNVEDYRKLAQKRLPKMVYDYLEGGAEDEYGVKHNRDVFQQWRFKPKRLVDVSRR 60 Query: 61 DLSTSVLGQRVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSWATSSIEEVAE 120 L VLG+R SMP+ +G TA+ G+LA RA G +LS+ + SIE++A Sbjct: 61 SLQAEVLGKRQSMPLLIGPTALNGALWPKGDLALARAATKAGIPFVLSTASNMSIEDLAR 120 Query: 121 AGPEALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKLPPQ 180 L W QLY+ RE+ + +V +A GY + +T D G R D+ NRFK+PP Sbjct: 121 QCDGDL-WFQLYVIH-REIAQGMVLKALHTGYTTLVLTTDVAVNGYRERDLHNRFKIPPF 178 Query: 181 LRMKNFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVAKGILR 240 L +KNFE L + N AA +++ +D S +WE ++WLR L ++ KG+L Sbjct: 179 LTLKNFEGIDLGKMDKANL---EMQAALMSRQMDASFNWEALRWLRDLWPHKLLVKGLLS 235 Query: 241 GDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDV 300 +DA + G +G+++SNHG RQLD + ++VL + V A GK V +D G R+G+D+ Sbjct: 236 AEDADRCIAEGADGVILSNHGGRQLDCAISPMEVLAQSV-AKTGK-PVLIDSGFRRGSDI 293 Query: 301 LKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDKTLV 360 +KALALGA+AV +GR ++GLA +GE GV +VL +LK + +A GC ++ + + Sbjct: 294 VKALALGAEAVLLGRATLYGLAARGETGVDEVLTLLKADIDRTLAQIGCPDITSLSPDYL 353 Query: 361 RK 362 + Sbjct: 354 QN 355 >2J6X-A nrPDB Length = 374 Score = 433 bits (1112), Expect = e-122, Method: Composition-based stats. Identities = 123/363 (33%), Positives = 188/363 (51%), Gaps = 13/363 (3%) Query: 4 RLICINDYEQHAKSVLPKSIYDYYRSGANDEETLADNIAAFSRWKLYPRMLRNVAETDLS 63 ++ D E+ A V+P ++Y + DE T N A+ LYPR+ ++V D S Sbjct: 18 DVVNTYDLEEEASKVVPHGGFNYIAGASGDEWTKRANDRAWKHKLLYPRLAQDVEAPDTS 77 Query: 64 TSVLGQRVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSWATSSIEEVAEAGP 123 T +LG ++ P + A +AH E T RA GT M +S+++ ++ EE++E Sbjct: 78 TEILGHKIKAPFIMAPIAAHGLAHTTKEAGTARAVSEFGTIMSISAYSGATFEEISEGLN 137 Query: 124 EALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKLPPQLRM 183 RW Q+Y+ KD + + ++ +A+ G AI +T D+ GNR DV+N+F P + + Sbjct: 138 GGPRWFQIYMAKDDQQNRDILDEAKSDGATAIILTADSTVSGNRDRDVKNKFVYPFGMPI 197 Query: 184 --KNFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVAKGILRG 241 + + S +G A IS DI+ + + LP+ KGI Sbjct: 198 VQRYLRGTAEGMSLNNIYG-----------ASKQKISPRDIEEIAAHSGLPVFVKGIQHP 246 Query: 242 DDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVL 301 +DA A+K G +GI VSNHGARQL P + D LP I E V +V + D GVR+G V Sbjct: 247 EDADMAIKAGASGIWVSNHGARQLYEAPGSFDTLPAIAERVNKRVPIVFDSGVRRGEHVA 306 Query: 302 KALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDKTLVR 361 KALA GA V +GRP+++GLA G +G VL+ +++ M L+G QNV+ + + Sbjct: 307 KALASGADVVALGRPVLFGLALGGWQGAYSVLDYFQKDLTRVMQLTGSQNVEDLKGLDLF 366 Query: 362 KNP 364 NP Sbjct: 367 DNP 369 >6DVI-A nrPDB Length = 394 Score = 428 bits (1101), Expect = e-120, Method: Composition-based stats. Identities = 131/365 (35%), Positives = 194/365 (53%), Gaps = 13/365 (3%) Query: 9 NDYEQHAKSVLPKSIYDYYRSGANDEETLADNIAAFSRWKLYPRMLRNVAETDLSTSVLG 68 D+E HA+ LP + Y G+ DE T N+ AF W L PRML E DLS + G Sbjct: 28 ADWEAHAQQALPPGVLSYVAGGSGDEHTQRANVEAFKHWGLMPRMLMAATERDLSVELWG 87 Query: 69 QRVSMPICVGATAMQRMAHVD--GELATVRACQSLGTGMMLSSWATSSIEEVAEAGPEAL 126 + + P+ + + D G+ A+ +A G + S+ A SS+E++ + + Sbjct: 88 KTWAAPMFFAPIGVIALCAQDGHGDAASAQASARTGVPYITSTLAVSSLEDIRKHAGDTP 147 Query: 127 RWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVR-NRFKLPPQLRMKN 185 + QLY +DR++ + +R+AE+ GY + +T+DT G R D+ + F L + N Sbjct: 148 AYFQLYYPEDRDLAESFIRRAEEAGYDGLVITLDTWIFGWRPRDLTISNFPFLRGLCLTN 207 Query: 186 FETSTL--------SFSPEENFGDDSGLAA-YVAKAIDPSISWEDIKWLRRLTSLPIVAK 236 + T + S E D+ LAA + S++WEDI W+R +T +P++ K Sbjct: 208 YVTDPVFQKKFKAHSGVEAEGLRDNPRLAADFWHGLFGHSVTWEDIDWVRSITKMPVILK 267 Query: 237 GILRGDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRK 296 GI DDAR AV G++GI SNHG RQ +G +D LPE+V+A G V D G+R Sbjct: 268 GIQHPDDARRAVDSGVDGIYCSNHGGRQANGGLPALDCLPEVVKA-SGDTPVLFDSGIRT 326 Query: 297 GTDVLKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVID 356 G DV+KALA+GA AV +GRP WG A G KG++ V L E L MA+ G +N+K + Sbjct: 327 GADVVKALAMGASAVGIGRPYAWGAALGGSKGIEHVARSLLAEADLIMAVDGYRNLKELT 386 Query: 357 KTLVR 361 +R Sbjct: 387 IDALR 391 >6BFG-A nrPDB Length = 399 Score = 404 bits (1038), Expect = e-113, Method: Composition-based stats. Identities = 129/378 (34%), Positives = 197/378 (52%), Gaps = 20/378 (5%) Query: 1 MLPRLICINDYEQHAKSVLPKSIYDYYRSGANDEETLADNIAAFSRWKLYPRMLRNVAET 60 M L + DY + + LPK +YDY GA DE + N F +W+ P+ L +V+ Sbjct: 1 MSQNLFNVEDYRKLRQKRLPKMVYDYLEGGAEDEYGVKHNRDVFQQWRFKPKRLVDVSRR 60 Query: 61 DLSTSVLGQRVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSWATSSIEEVAE 120 L VLG+R SMP+ +G T + G+LA RA G +LS+ + SIE++A Sbjct: 61 SLQAEVLGKRQSMPLLIGPTGLNGALWPKGDLALARAATKAGIPFVLSTASNMSIEDLAR 120 Query: 121 AGPEALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKLPPQ 180 L W QLY+ RE+ + +V +A GY + +T D G R D+ NRFK+P Sbjct: 121 QCDGDL-WFQLYVIH-REIAQGMVLKALHTGYTTLVLTTDVAVNGYRERDLHNRFKIPMS 178 Query: 181 LRMKNFETSTL-----------SFSPEENFGDDS-----GLAAYVAKAIDPSISWEDIKW 224 K L NF AA +++ +D S +WE ++W Sbjct: 179 YSAKVVLDGCLHPRWSLDFVRHGMPQLANFVSSQTSSLEMQAALMSRQMDASFNWEALRW 238 Query: 225 LRRLTSLPIVAKGILRGDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEG 284 LR L ++ KG+L +DA + G +G+++SNHG RQLD + ++VL + V A G Sbjct: 239 LRDLWPHKLLVKGLLSAEDADRCIAEGADGVILSNHGGRQLDCAISPMEVLAQSV-AKTG 297 Query: 285 KVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAM 344 K V +D G R+G+D++KALALGA+AV +GR ++GLA +GE GV +VL +LK + + Sbjct: 298 K-PVLIDSGFRRGSDIVKALALGAEAVLLGRATLYGLAARGETGVDEVLTLLKADIDRTL 356 Query: 345 ALSGCQNVKVIDKTLVRK 362 A GC ++ + ++ Sbjct: 357 AQIGCPDITSLSPDYLQN 374 >2CDH-0 nrPDB Length = 226 Score = 254 bits (649), Expect = 4e-68, Method: Composition-based stats. Identities = 126/286 (44%), Positives = 170/286 (59%), Gaps = 60/286 (20%) Query: 63 STSVLGQRVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSWATSSIEEVAEAG 122 +T++LG ++SMPI + TAMQ+MAH +GE AT RA + GT M LSSWATSS+EEVA G Sbjct: 1 TTTILGFKISMPIMIAPTAMQKMAHPEGEYATARAASAAGTIMTLSSWATSSVEEVASTG 60 Query: 123 PEALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKLPPQLR 182 P +R+ QLY+ + +V + Sbjct: 61 P-GIRFFQLYV--------------------------------YKDRNVVAQLV------ 81 Query: 183 MKNFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVAKGILRGD 242 KAI ++ W+D+ WL+ +TSLPI+ KG++ + Sbjct: 82 --------------------RRAERAGFKAIALTV-WKDVAWLQTITSLPILVKGVITAE 120 Query: 243 DAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLK 302 DAR AV+HG GI+VSNHGARQLD VPATI L E+V+A +G++ VFLDGGVR+GTDV K Sbjct: 121 DARLAVQHGAAGIIVSNHGARQLDYVPATIMALEEVVKAAQGRIPVFLDGGVRRGTDVFK 180 Query: 303 ALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSG 348 ALALGA VF+GRP+V+ LA +GE GV+ VL+++++EF L MALSG Sbjct: 181 ALALGAAGVFIGRPVVFSLAAEGEAGVKKVLQMMRDEFELTMALSG 226 >5LSM-A nrPDB Length = 359 Score = 94.4 bits (233), Expect = 7e-20, Method: Composition-based stats. Identities = 34/125 (27%), Positives = 54/125 (43%), Gaps = 15/125 (12%) Query: 210 AKAIDPSISWEDIKWLRRLTSLPIVAKGILRGDDAREAVKHGLNGILVSNHGARQLDGVP 269 +K I + + E+ WL + I+A+G+ G G G +S QL Sbjct: 149 SKVISTATTVEEALWLEARGADAIIAQGLEAG---------GHRGHFLSEDLTEQL---- 195 Query: 270 ATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKGV 329 T +LP+I+ AVE + V GG+ T V A+ +GA AV VG + Sbjct: 196 GTFSLLPQIIAAVE--IPVIAAGGIVDATTVRAAMTMGASAVQVGTAYLLCPECNTSAIH 253 Query: 330 QDVLE 334 ++ L+ Sbjct: 254 REALQ 258 >3SR7-A nrPDB Length = 365 Score = 90.2 bits (222), Expect = 1e-18, Method: Composition-based stats. Identities = 58/317 (18%), Positives = 111/317 (35%), Gaps = 47/317 (14%) Query: 56 NVAETDLSTSVLGQRVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSWATSSI 115 ++AE DLST GQ P + A + + + G + S++T+ Sbjct: 70 DLAEIDLSTHFAGQDFDFPFYINAMTGGSQKGKEVNEKLAQVADTCGLLFVTGSYSTA-- 127 Query: 116 EEVAEAGPEALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLG--NRLDDVRN 173 K+ + T V+++ A + +D PY + D++ Sbjct: 128 ------------------LKNPDDTSYQVKKSRPHLLLATNIGLDKPYQAGLQAVRDLQ- 168 Query: 174 RFKLPPQLRMKNFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPI 233 P L++ ++ E + K + + ++ + + Sbjct: 169 ----PLFLQVH------INLMQELLMPEGEREFRSWKKHLSDYAKKLQLPFILKEVGFGM 218 Query: 234 VAKGILRGDD-----AREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVE---GK 285 K I D + + G + + N + +++ + K Sbjct: 219 DVKTIQTAIDLGVKTVDISGRGGTSFAYIENRRGGNRSYLNQWGQTTAQVLLNAQPLMDK 278 Query: 286 VEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEIL---KEEFRL 342 VE+ GG+R D++KAL LGAKAV + R + L + V +V+ I+ KE+ RL Sbjct: 279 VEILASGGIRHPLDIIKALVLGAKAVGLSRTM---LELVEQHSVHEVIAIVNGWKEDLRL 335 Query: 343 AMALSGCQNVKVIDKTL 359 M CQ + + Sbjct: 336 IMCALNCQTIAELRNVD 352 >4N02-A nrPDB Length = 357 Score = 84.0 bits (206), Expect = 1e-16, Method: Composition-based stats. Identities = 67/327 (20%), Positives = 113/327 (34%), Gaps = 63/327 (19%) Query: 54 LRNVAETDLSTSVLGQRVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSWATS 113 L N+ E DLST G++ P + A + + +S G + S++ + Sbjct: 56 LYNLDEIDLSTEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAA 115 Query: 114 SIEEVAEAGPEALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPY-LGNRLDDVR 172 L D + V+ + + +D P LG + + Sbjct: 116 -----------------LKNPTDDSFS---VKSSHPNLLLGTNIGLDKPVELGLQTVEEM 155 Query: 173 NRFKLPPQLRMKNFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLP 232 N L + + E F A +K I +P Sbjct: 156 NPVLLQVHVNVMQELLMPEG---ERKFRSWQSHLADYSKQI----------------PVP 196 Query: 233 IVAKGILRGDDA---REAVKHGLNGILVSNHGARQLDGV----PATIDVLPE----IVEA 281 IV K + G DA A + G+ + +S G + D L + ++A Sbjct: 197 IVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRRSGQRDYLNQWGQSTMQA 256 Query: 282 V------EGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEI 335 + + KVE+ + GGVR D++K L GAKAV + R + L V++V+ I Sbjct: 257 LLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRTV---LELVETYTVEEVIGI 313 Query: 336 L---KEEFRLAMALSGCQNVKVIDKTL 359 + K + RL M C + + K Sbjct: 314 VQGWKADLRLIMCSLNCATIADLQKVD 340 >2ZRW-A nrPDB Length = 368 Score = 81.3 bits (199), Expect = 7e-16, Method: Composition-based stats. Identities = 28/108 (25%), Positives = 50/108 (46%), Gaps = 2/108 (1%) Query: 253 NGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVF 312 G + LD T + E+ +V + GG+R G D KA+ALGA Sbjct: 236 RGNWKAESAKNFLDWGVPTAASIMEVRYSVPDSF-LVGSGGIRSGLDAAKAIALGADIAG 294 Query: 313 VGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDKTLV 360 + P++ A +G++ ++ + E + AM L+G ++V + KT + Sbjct: 295 MALPVLKS-AIEGKESLEQFFRKIIFELKAAMMLTGSKDVDALKKTSI 341 >1P0K-A nrPDB Length = 349 Score = 77.9 bits (190), Expect = 7e-15, Method: Composition-based stats. Identities = 53/330 (16%), Positives = 110/330 (33%), Gaps = 71/330 (21%) Query: 55 RNVAETDLSTSVLGQRVSMPICVGA-TAMQRMAHVDGELATVRACQSLGTGMMLSSWATS 113 + + D+ST + S PI + A T + + RA G + + S ++ Sbjct: 38 LALEQVDISTKIGELSSSSPIFINAMTGGGGKLTYEINKSLARAASQAGIPLAVGSQMSA 97 Query: 114 --------SIEEVAEAGPEALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLG 165 S E V + P L + L + E +G A+ + ++ Sbjct: 98 LKDPSERLSYEIVRKENPNGLIFANL---GSEATAAQAKEAVEMIGANALQIHLN----- 149 Query: 166 NRLDDVRNRFKLPPQLRMKNFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWL 225 V +P + A+ I+ + Sbjct: 150 -----VIQEIVMPEG-------------------------DRSFSGALKR------IEQI 173 Query: 226 RRLTSLPIVAKGI---LRGDDAREAVKHGLNGILVSNHGA------------RQLDGVPA 270 S+P++ K + + A + + G + + +G RQ+ + Sbjct: 174 CSRVSVPVIVKEVGFGMSKASAGKLYEAGAAAVDIGGYGGTNFSKIENLRRQRQISFFNS 233 Query: 271 TIDVLPEIVEAVEGKVE---VFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEK 327 + + + + GG++ DV KA+ALGA + + L GE+ Sbjct: 234 WGISTAASLAEIRSEFPASTMIASGGLQDALDVAKAIALGASCTGMAGHFLKALTDSGEE 293 Query: 328 GVQDVLEILKEEFRLAMALSGCQNVKVIDK 357 G+ + ++++ EE +L M + G + + + K Sbjct: 294 GLLEEIQLILEELKLIMTVLGARTIADLQK 323 >4Q4K-A nrPDB Length = 357 Score = 59.0 bits (141), Expect = 3e-09, Method: Composition-based stats. Identities = 57/281 (20%), Positives = 97/281 (34%), Gaps = 29/281 (10%) Query: 60 TDLSTSVLGQRVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSWATSSIEEVA 119 TD T +LG + PI M ++ A A LG+ + S A + Sbjct: 2 TDRFTRLLG--IQQPIIQAP--MLGVSTPALAAAVSNAGG-LGSIAITGSAAEKGRALIR 56 Query: 120 EAGPEALRWLQLYIYKDREVTKKLVRQAEKMGY-KAIF--VTVDTPYLGNRLDDVRNRFK 176 E + + ++ R R+ + Y K +F + P RL ++ F Sbjct: 57 EVRGLTDKPFNVNLFCHRPGQADPARERAWLDYLKPLFAEFGAEPPV---RLKNIYLSFL 113 Query: 177 LPPQLRMKNFETSTLSFSPEENFGDDSGLAAYVA---KAIDPSISWEDIKWLRRLTSLPI 233 P L E + S + A A + + + + E+ + + + Sbjct: 114 EDPTLLPMLLEERPAAVSFHFGAPPRDQVRALQAVGIRVLVCATTPEEAALVEAAGADAV 173 Query: 234 VAKGILRGDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGG 293 VA+GI G G G+ G D T+ ++ + A G + V GG Sbjct: 174 VAQGIEAG---------GHRGVFEPERG----DAAIGTLALVR--LLAARGSLPVVAAGG 218 Query: 294 VRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLE 334 + G + AL LGA AV +G V ++ L+ Sbjct: 219 IMDGRGIRAALELGASAVQMGTAFVLCPESSANAAYREALK 259 >3FFS-A nrPDB Length = 400 Score = 49.0 bits (115), Expect = 3e-06, Method: Composition-based stats. Identities = 25/115 (21%), Positives = 51/115 (44%), Gaps = 7/115 (6%) Query: 220 EDIKWLRRLTSLPIVAKGILRGDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIV 279 +K ++ ++ ++ ++ + +E +++G +GI V +P+I Sbjct: 174 RTLKEIKSKMNIDVIVGNVVTEEATKELIENGADGIKVGIGPGSICTTRIVAGVGVPQIT 233 Query: 280 E-------AVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEK 327 A + + + DGG+R D+ KALA+GA +V +G + GEK Sbjct: 234 AIEKCSSVASKFGIPIIADGGIRYSGDIGKALAVGASSVMIGSILAGTEESPGEK 288 >4QJ1-A nrPDB Length = 361 Score = 48.6 bits (114), Expect = 4e-06, Method: Composition-based stats. Identities = 25/115 (21%), Positives = 51/115 (44%), Gaps = 7/115 (6%) Query: 220 EDIKWLRRLTSLPIVAKGILRGDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIV 279 +K ++ ++ ++ ++ + +E +++G +GI V +P+I Sbjct: 135 RTLKEIKSKMNIDVIVGNVVTEEATKELIENGADGIKVGIGPGSICTTRIVAGVGVPQIT 194 Query: 280 E-------AVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEK 327 A + + + DGG+R D+ KALA+GA +V +G + GEK Sbjct: 195 AIEKCSSVASKFGIPIIADGGIRYSGDIGKALAVGASSVMIGSILAGTEESPGEK 249 >1VRD-A nrPDB Length = 494 Score = 48.6 bits (114), Expect = 4e-06, Method: Composition-based stats. Identities = 30/114 (26%), Positives = 47/114 (41%), Gaps = 19/114 (16%) Query: 231 LPIVAKGILRGDDAREAVKHGLNGI-------------LVSNHGARQLDGVPATIDVLPE 277 LP+VA + + +K G + + +V+ G QL V +V Sbjct: 279 LPVVAGNVATPEGTEALIKAGADAVKVGVGPGSICTTRVVAGVGVPQLTAVMECSEV--- 335 Query: 278 IVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKGVQD 331 A + V + DGG+R D++KALA GA++V VG GE + Sbjct: 336 ---ARKYDVPIIADGGIRYSGDIVKALAAGAESVMVGSIFAGTEEAPGETILYQ 386 >4Z87-A nrPDB Length = 525 Score = 47.0 bits (110), Expect = 1e-05, Method: Composition-based stats. Identities = 37/222 (16%), Positives = 72/222 (32%), Gaps = 42/222 (18%) Query: 168 LDDVRNRFKLPPQLRMKNFETSTLSFSPEENFGDDSGLAAYV----------AKAIDPSI 217 D+ P + + + + D LA V + + Sbjct: 229 RTDLMKNQSYPLASKSADTKQLLCGAAIGTIDADRQRLAMLVEAGLDVVVLDSSQGNSVF 288 Query: 218 SWEDIKWLRRLTS-LPIVAKGILRGDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLP 276 IKW++ L ++A ++ + A + G +G+ ++ +I + Sbjct: 289 QINMIKWIKETFPDLQVIAGNVVTREQAASLIHAGADGL--------RIGMGSGSICITQ 340 Query: 277 EIVE---------------AVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGL 321 E++ A + V DGGV+ + KA+ALGA V +G + Sbjct: 341 EVMACGRPQGTAVYNVTQFANQFGVPCIADGGVQNIGHITKAIALGASTVMMGGMLAGTT 400 Query: 322 AFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDKTLVRKN 363 GE + + G ++ + KT V+ N Sbjct: 401 ESPGE--------YFFRDGKRLKTYRGMGSIDAMQKTDVKGN 434 >4XTI-A nrPDB Length = 413 Score = 45.9 bits (107), Expect = 3e-05, Method: Composition-based stats. Identities = 31/170 (18%), Positives = 61/170 (35%), Gaps = 32/170 (18%) Query: 210 AKAIDPSISWEDIKWLRRLTS-LPIVAKGILRGDDAREAVKHGLNGILVSNHGARQLDGV 268 + + IKW++ L ++A ++ + A + G +G+ ++ Sbjct: 169 SSQGNSVFQINMIKWIKETFPDLQVIAGNVVTREQAASLIHAGADGL--------RIGMG 220 Query: 269 PATIDVLPEIVE---------------AVEGKVEVFLDGGVRKGTDVLKALALGAKAVFV 313 +I + E++ A + V DGGV+ + KA+ALGA V + Sbjct: 221 SGSICITQEVMACGRPQGTAVYNVTQFANQFGVPCIADGGVQNIGHITKAIALGASTVMM 280 Query: 314 GRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDKTLVRKN 363 G + GE + + G ++ + KT V+ N Sbjct: 281 GGMLAGTTESPGE--------YFFRDGKRLKTYRGMGSIDAMQKTDVKGN 322 >3DH7-A nrPDB Length = 332 Score = 45.9 bits (107), Expect = 3e-05, Method: Composition-based stats. Identities = 81/331 (24%), Positives = 118/331 (35%), Gaps = 54/331 (16%) Query: 46 RWKLYPRMLRNVAETDLSTSVLGQRVSMPICVGATAMQRMAHVDGELATVRACQSLGTGM 105 R + ++E DL+T LG+ + P +GA LA A ++LG GM Sbjct: 32 RLRYQALAGLALSEVDLTTPFLGKTLKAPFLIGAMTGGEENGERINLALAEAAEALGVGM 91 Query: 106 MLSSW--------ATSSIEEVAEAGPEALRWLQLYIYKDREVT-KKLVRQAEKMGYKAIF 156 ML S A S V + P+AL L + + R L+R E + A+ Sbjct: 92 MLGSGRILLERPEALRSFR-VRKVAPKALLIANLGLAQLRRYGRDDLLRLVEMLEADALA 150 Query: 157 VTV----------DTPYLGNRLDDVRNRFKLPPQLRMKNFETSTLSFSPEENFGDDSGLA 206 V DT + G + LP + +K LS D A Sbjct: 151 FHVNPLQEAVQRGDTDFRGLVER-LAELLPLPFPVMVKEV-GHGLSREAALALRDLPLAA 208 Query: 207 AYVAKAIDPSISWEDIKWLRRLTSLPIVAKGILRGDDAREAVKHGLNGILVSNHGARQLD 266 VA A S W ++ R + + + AR + Sbjct: 209 VDVAGAGGTS--WARVEEWVRFGE-------VRHPELCEIGIPT-----------ARAIL 248 Query: 267 GVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGE 326 V +VLP + + GGV GTD KALALGA + V RP++ A +G Sbjct: 249 EVR---EVLPH--------LPLVASGGVYTGTDGAKALALGADLLAVARPLLRP-ALEGA 296 Query: 327 KGVQDVLEILKEEFRLAMALSGCQNVKVIDK 357 + V + EE R A+ G +N K Sbjct: 297 ERVAAWIGDYLEELRTALFAIGARNPKEARG 327 >4FXS-A nrPDB Length = 496 Score = 45.9 bits (107), Expect = 3e-05, Method: Composition-based stats. Identities = 27/103 (26%), Positives = 41/103 (39%), Gaps = 7/103 (6%) Query: 231 LPIVAKGILRGDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVE-------AVE 283 L I+ + + AR ++ G++ + V T +P+I A E Sbjct: 273 LEIIGGNVATAEGARALIEAGVSAVKVGIGPGSICTTRIVTGVGVPQITAIADAAGVANE 332 Query: 284 GKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGE 326 + V DGG+R D+ KA+A GA V VG GE Sbjct: 333 YGIPVIADGGIRFSGDISKAIAAGASCVMVGSMFAGTEEAPGE 375 >4FEZ-A nrPDB Length = 388 Score = 45.5 bits (106), Expect = 4e-05, Method: Composition-based stats. Identities = 27/103 (26%), Positives = 41/103 (39%), Gaps = 7/103 (6%) Query: 231 LPIVAKGILRGDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVE-------AVE 283 L I+ + + AR ++ G++ + V T +P+I A E Sbjct: 172 LEIIGGNVATAEGARALIEAGVSAVKVGIGPGSICTTRIVTGVGVPQITAIADAAGVANE 231 Query: 284 GKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGE 326 + V DGG+R D+ KA+A GA V VG GE Sbjct: 232 YGIPVIADGGIRFSGDISKAIAAGASCVMVGSMFAGTEEAPGE 274 >4MJM-A nrPDB Length = 385 Score = 45.5 bits (106), Expect = 4e-05, Method: Composition-based stats. Identities = 50/229 (21%), Positives = 86/229 (37%), Gaps = 30/229 (13%) Query: 118 VAEAGPEALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKL 177 +A G + + I + E K V+++E G K I ++ P N D + R + Sbjct: 66 MARQGGLGIIHKNMSIEQQAEQVDK-VKRSESGGIKDIEKVIEFP---NSAKDKQGRLLV 121 Query: 178 PPQLRMKNFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWED-IKWLRRLTS-LPIVA 235 + + + + + + A + A S D +K +R L I+A Sbjct: 122 GAAVGVTADAMTRIDALVKASVD-----AIVLDTAHGHSQGVIDKVKEVRAKYPSLNIIA 176 Query: 236 KGILRGDDAREAVKHGLN----GI---------LVSNHGARQLDGVPATIDVLPEIVEAV 282 + + + ++ G N GI +V+ G QL A D E A Sbjct: 177 GNVATAEATKALIEAGANVVKVGIGPGSICTTRVVAGVGVPQL---TAVYDCATE---AR 230 Query: 283 EGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKGVQD 331 + + V DGG++ D++KALA GA V +G GE + Sbjct: 231 KHGIPVIADGGIKYSGDMVKALAAGAHVVMLGSMFAGVAESPGETEIYQ 279 >2GJN-A nrPDB Length = 328 Score = 45.1 bits (105), Expect = 5e-05, Method: Composition-based stats. Identities = 25/117 (21%), Positives = 47/117 (40%), Gaps = 8/117 (6%) Query: 252 LNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAV 311 ++G + H D +P + +LP + +V + GG G ++ ALALGA A+ Sbjct: 144 IDGFECAGHPGE--DDIPG-LVLLPAAANRL--RVPIIASGGFADGRGLVAALALGADAI 198 Query: 312 FVGRPIVWGLAFQGEKGVQDVLEILKE-EFRLAMALSGCQNVKVIDKTLVRKNPLAV 367 +G + V+ + E L M +N + + + + LA+ Sbjct: 199 NMGTRFLATRECPIHPAVKAAIRAADERSTDLIMRSL--RNTARVARNAISQEVLAI 253 >1JCN-A nrPDB Length = 514 Score = 43.2 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 23/108 (21%), Positives = 44/108 (40%), Gaps = 7/108 (6%) Query: 226 RRLTSLPIVAKGILRGDDAREAVKHGLNGILVSNHGA------RQLDGVPATIDVLPEIV 279 ++ L ++ ++ A+ + G++G+ V + + ++ Sbjct: 292 QKYPHLQVIGGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVA 351 Query: 280 E-AVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGE 326 E A V + DGG++ V+KALALGA V +G + GE Sbjct: 352 EYARRFGVPIIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGE 399 >6I0M-A nrPDB Length = 517 Score = 42.8 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 30/176 (17%), Positives = 61/176 (34%), Gaps = 17/176 (9%) Query: 168 LDDVRNRFKLP---PQLRMKNFETSTLSFSPEENFGDDSGLAAYV------AKAIDPSIS 218 D++ P + + + + ++ + D A V + + Sbjct: 227 RTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQ 286 Query: 219 WEDIKWLRRLTS-LPIVAKGILRGDDAREAVKHGLNGILVSNHGA------RQLDGVPAT 271 IK+++ L ++ ++ A+ + G++ + V L Sbjct: 287 INMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQ 346 Query: 272 IDVLPEIVE-AVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGE 326 + ++ E A V V DGG++ + KALALGA V +G + GE Sbjct: 347 ATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGE 402 >4AF0-B nrPDB Length = 556 Score = 42.8 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 24/111 (21%), Positives = 46/111 (41%), Gaps = 24/111 (21%) Query: 220 EDIKWL-RRLTSLPIVAKGILRGDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEI 278 E IKW+ + + ++A ++ + A + + G +G+ ++ +I + E+ Sbjct: 311 EFIKWIKQTYPKIDVIAGNVVTREQAAQLIAAGADGL--------RIGMGSGSICITQEV 362 Query: 279 VE---------------AVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVG 314 + A + DGG+ + KALALGA AV +G Sbjct: 363 MAVGRPQGTAVYAVAEFASRFGIPCIADGGIGNIGHIAKALALGASAVMMG 413 >4DQW-A nrPDB Length = 509 Score = 42.4 bits (98), Expect = 3e-04, Method: Composition-based stats. Identities = 18/60 (30%), Positives = 26/60 (43%), Gaps = 1/60 (1%) Query: 268 VPATIDVLPEIVEAVEGK-VEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGE 326 I + + A+EG V + DGG+R D+ KA+ GA V +G GE Sbjct: 333 GVPQISAIANVAAALEGTGVPLIADGGIRFSGDLAKAMVAGAYCVMMGSMFAGTEEAPGE 392 >3TSB-A nrPDB Length = 511 Score = 42.4 bits (98), Expect = 3e-04, Method: Composition-based stats. Identities = 32/124 (25%), Positives = 50/124 (40%), Gaps = 20/124 (16%) Query: 222 IKWLRRLTS-LPIVAKGILRGDDAREAVKHGLN----GI---------LVSNHGARQLDG 267 +K +R L I+A + + + ++ G N GI +V+ G QL Sbjct: 288 VKEVRAKYPSLNIIAGNVATAEATKALIEAGANVVKVGIGPGSICTTRVVAGVGVPQL-- 345 Query: 268 VPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEK 327 A D E A + + V DGG++ D++KALA GA V +G GE Sbjct: 346 -TAVYDCATE---ARKHGIPVIADGGIKYSGDMVKALAAGAHVVMLGSMFAGVAESPGET 401 Query: 328 GVQD 331 + Sbjct: 402 EIYQ 405 >5AHL-A nrPDB Length = 400 Score = 42.0 bits (97), Expect = 4e-04, Method: Composition-based stats. Identities = 18/60 (30%), Positives = 26/60 (43%), Gaps = 1/60 (1%) Query: 268 VPATIDVLPEIVEAVEGK-VEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGE 326 I + + A+EG V + DGG+R D+ KA+ GA V +G GE Sbjct: 224 GVPQISAIANVAAALEGTGVPLIADGGIRFSGDLAKAMVAGAYCVMMGSMFAGTEEAPGE 283 >3BW4-A nrPDB Length = 369 Score = 41.7 bits (96), Expect = 5e-04, Method: Composition-based stats. Identities = 29/153 (18%), Positives = 57/153 (37%), Gaps = 14/153 (9%) Query: 215 PSISWEDIKWLRRLTSLPIVAKGILRGDDAREAVKHGLNGILVSNHGARQLDGVPATIDV 274 + + E+ + + + ++A+G+ G G G + + + Sbjct: 151 TATTPEEARAVEAAGADAVIAQGVEAG---------GHQG--THRDSSEDDGAGIGLLSL 199 Query: 275 LPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKGVQDVL- 333 L ++ EAV + V GG+ +G + LA GA A +G + + L Sbjct: 200 LAQVREAV--DIPVVAAGGIMRGGQIAAVLAAGADAAQLGTAFLATDESGAPGPHKRALT 257 Query: 334 EILKEEFRLAMALSGCQNVKVIDKTLVRKNPLA 366 + L RL A +G ++++ L P A Sbjct: 258 DPLFARTRLTRAFTGRPARSLVNRFLREHGPYA 290 >5UQG-A nrPDB Length = 406 Score = 41.7 bits (96), Expect = 6e-04, Method: Composition-based stats. Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 1/48 (2%) Query: 268 VPATIDVLPEIVEAVEG-KVEVFLDGGVRKGTDVLKALALGAKAVFVG 314 I + E VE V V DGG++ D+ KALA+GA +V +G Sbjct: 231 GVPQISAIDECVEEANKFGVPVIADGGIKYSGDIAKALAVGASSVMIG 278 >2Z6J-A nrPDB Length = 332 Score = 41.3 bits (95), Expect = 7e-04, Method: Composition-based stats. Identities = 28/134 (20%), Positives = 48/134 (35%), Gaps = 2/134 (1%) Query: 233 IVAKGILRGDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDG 292 IV + A+ K G + ++ A G T+ ++ ++ A+ + V G Sbjct: 112 IVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATAIS--IPVIAAG 169 Query: 293 GVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNV 352 G+ G LGA+AV VG V ++ + ++ A V Sbjct: 170 GIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDTTISAQHFGHAV 229 Query: 353 KVIDKTLVRKNPLA 366 + I L R LA Sbjct: 230 RAIKNQLTRDFELA 243 >1ZFJ-A nrPDB Length = 491 Score = 40.5 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 27/121 (22%), Positives = 43/121 (35%), Gaps = 10/121 (8%) Query: 220 EDIKWLRRLTSLPIVAKG-ILRGDDAREAVKHGLN--------GILVSNHGARQLDGVPA 270 I +R + G I + AR G++ G + + + GVP Sbjct: 263 RKIAEIRAHFPNRTLIAGNIATAEGARALYDAGVDVVKVGIGPGSICTTRVVAGV-GVPQ 321 Query: 271 TIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKGVQ 330 + A E + DGG++ D++KALA G AV +G GE + Sbjct: 322 VTAIYDAAAVAREYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIY 381 Query: 331 D 331 Sbjct: 382 Q 382 >1TV5-A nrPDB Length = 443 Score = 40.1 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 38/250 (15%), Positives = 84/250 (33%), Gaps = 42/250 (16%) Query: 138 EVTKKLVRQAEKMG--YKAIFVTVDTP----YLGNRLDDVRNRFKLPPQLRMKNFETSTL 191 + L K+G I + V +P N+ L + + N E + + Sbjct: 194 NIVDDLKYCINKIGRYADYIAINVSSPNTPGLRDNQEAGKLKNIILSVKEEIDNLEKNNI 253 Query: 192 SFSPEENFGDDSGLAAYVAKAIDPSISWEDIK----WLRRLTSLPIVAKGI-------LR 240 D+ + + S +D K W P+V + + Sbjct: 254 MNDESTYNEDNKIVEKKNNFNKNNSHMMKDAKDNFLWFNTTKKKPLVFVKLAPDLNQEQK 313 Query: 241 GDDAREAVKHGLNGILVSNHGARQLDGVPA----------------TIDVLPEIVEAVEG 284 + A ++ ++G+++SN Q++ + + + + E+ Sbjct: 314 KEIADVLLETNIDGMIISN-TTTQINDIKSFENKKGGVSGAKLKDISTKFICEMYNYTNK 372 Query: 285 KVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAM 344 ++ + GG+ G D L+ + GA + +V+ G++ ++I K E + Sbjct: 373 QIPIIASGGIFSGLDALEKIEAGASVCQLYSCLVF-------NGMKSAVQI-KRELNHLL 424 Query: 345 ALSGCQNVKV 354 G N+K Sbjct: 425 YQRGYYNLKE 434 >5UPU-A nrPDB Length = 407 Score = 40.1 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 18/60 (30%), Positives = 25/60 (41%) Query: 267 GVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGE 326 G P +L + V V DGG++ D+ KALA GA +G + GE Sbjct: 228 GAPQITAILEAVAACRPAGVPVIADGGLQYSGDIAKALAAGASTAMLGSLLAGTAEAPGE 287 >6I4B-A nrPDB Length = 405 Score = 39.7 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 24/158 (15%), Positives = 59/158 (37%), Gaps = 32/158 (20%) Query: 220 EDIKWLRRLTSLPIVAKGI-------LRGDDAREAVKHGLNGILVSNHGARQLDGVPA-- 270 ++ W P+V + + + A ++ ++G+++SN Q++ + + Sbjct: 248 DEFLWFNTTKKKPLVFVKLAPDLNQEQKKEIADVLLETNIDGMIISN-TTTQINDIKSFE 306 Query: 271 --------------TIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRP 316 + + E+ ++ + GG+ G D L+ + GA + Sbjct: 307 NKKGGVSGAKLKDISTKFICEMYNYTNKQIPIIASGGIFSGLDALEKIEAGASVCQLYSC 366 Query: 317 IVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKV 354 +V+ G++ ++I K E + G N+K Sbjct: 367 LVF-------NGMKSAVQI-KRELNHLLYQRGYYNLKE 396 >3OIX-A nrPDB Length = 345 Score = 39.3 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 16/91 (17%), Positives = 36/91 (39%), Gaps = 8/91 (8%) Query: 269 PATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKG 328 P + + + + +++ GGV+ G D + + GA V +G L +G Sbjct: 259 PTALANVHAFYKRLNPSIQIIGTGGVKTGRDAFEHILCGASMVQIGT----ALHQEGP-- 312 Query: 329 VQDVLEILKEEFRLAMALSGCQNVKVIDKTL 359 + + + +E + M G + ++ L Sbjct: 313 --QIFKRITKELKAIMTEKGYETLEDFRGKL 341 >2CU0-A nrPDB Length = 486 Score = 38.2 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 17/48 (35%), Positives = 26/48 (54%) Query: 280 EAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEK 327 A E + V DGG+R D++KA+A GA AV +G + G++ Sbjct: 323 RAQEYGLYVIADGGIRYSGDIVKAIAAGADAVMLGNLLAGTKEAPGKE 370 >1TYG-A nrPDB Length = 253 Score = 38.2 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 19/78 (24%), Positives = 29/78 (37%) Query: 240 RGDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTD 299 DD A K G+ GA + ++ L + KV V +D G+ D Sbjct: 131 TSDDVVLARKLEELGVHAIMPGASPIGSGQGILNPLNLSFIIEQAKVPVIVDAGIGSPKD 190 Query: 300 VLKALALGAKAVFVGRPI 317 A+ LGA V + + Sbjct: 191 AAYAMELGADGVLLNTAV 208 >4JDY-A nrPDB Length = 264 Score = 38.2 bits (87), Expect = 0.006, Method: Composition-based stats. Identities = 17/63 (26%), Positives = 28/63 (44%) Query: 267 GVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGE 326 + A +++ E+ A + V +F GG+ D + LGA+ VFVG I A + Sbjct: 183 ELQAPYELVAEVARAGKLPVTLFTAGGIATPADAAMMMQLGAEGVFVGSGIFKSGAPEHR 242 Query: 327 KGV 329 Sbjct: 243 AAA 245 >3U2O-A nrPDB Length = 395 Score = 37.8 bits (86), Expect = 0.007, Method: Composition-based stats. Identities = 33/131 (25%), Positives = 56/131 (42%), Gaps = 10/131 (7%) Query: 213 IDPSISWEDIKWLRRLTSLPIVAKGILRGDDAREAVKHGLNGILVSNHGARQLDGVPA-- 270 I P ++ +D + + + + G++ + + GL G L S G L G P Sbjct: 255 IAPDLTSQDKEDIASVVK-ELGIDGLIVT-NTTVSRPAGLQGALRSETGG--LSGKPLRD 310 Query: 271 -TIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRP-IVWGLAFQGEKG 328 + + E+ +G+V + GGV G D L+ + GA V + WG G+ Sbjct: 311 LSTQTIREMYALTQGRVPIIGVGGVSSGQDALEKIRAGASLVQLYTALTFWGPPVVGK-- 368 Query: 329 VQDVLEILKEE 339 V+ LE L +E Sbjct: 369 VKRELEALLKE 379 >4IQL-A nrPDB Length = 333 Score = 37.8 bits (86), Expect = 0.007, Method: Composition-based stats. Identities = 35/132 (26%), Positives = 55/132 (41%), Gaps = 11/132 (8%) Query: 234 VAKGILRGDDAREAVKHGLNGILVS--NHGARQLDGVPATIDVLPEIVEAVEGKVEVFLD 291 V + AR++ G++ I+ G T+ ++PE+V+AV + V Sbjct: 132 VIHVVSSATFARKSEAAGVDAIVAEGFEAGGHNGREETTTLCLIPEVVDAVN--IPVVAA 189 Query: 292 GGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQN 351 GG+ G V ALALGA AV VG A E + K R ++ + Sbjct: 190 GGIASGRAVAAALALGADAVQVGTRF----ALSEESSAHE---DFKAHCRRSVEGDTMLS 242 Query: 352 VKVIDKTLVRKN 363 +K + T + KN Sbjct: 243 LKAVSPTRLLKN 254 >1JUE-A nrPDB Length = 311 Score = 37.8 bits (86), Expect = 0.008, Method: Composition-based stats. Identities = 16/91 (17%), Positives = 35/91 (38%), Gaps = 8/91 (8%) Query: 269 PATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKG 328 P + + ++ ++++ GG+ G D + L GA + +G L +G Sbjct: 226 PTALANVRAFYTRLKPEIQIIGTGGIETGQDAFEHLLCGATMLQIGT----ALHKEGPA- 280 Query: 329 VQDVLEILKEEFRLAMALSGCQNVKVIDKTL 359 + + + +E M G Q++ L Sbjct: 281 ---IFDRIIKELEEIMNQKGYQSIADFHGKL 308 >1YPF-A nrPDB Length = 336 Score = 37.8 bits (86), Expect = 0.008, Method: Composition-based stats. Identities = 25/110 (22%), Positives = 36/110 (32%), Gaps = 16/110 (14%) Query: 218 SWEDIKWLRRLTSLPIVAKGILRGDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPE 277 + E ++ L + GI G +K G G QL L Sbjct: 159 TPEAVRELENAGADATKV-GIGPGKVCITKIKTGFGT------GGWQL-------AALRW 204 Query: 278 IVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEK 327 +A + DGG+R DV K++ GA V +G GE Sbjct: 205 CAKAASK--PIIADGGIRTNGDVAKSIRFGATMVMIGSLFAGHEESPGET 252 >2H6R-A nrPDB Length = 219 Score = 37.4 bits (85), Expect = 0.009, Method: Composition-based stats. Identities = 19/70 (27%), Positives = 32/70 (45%), Gaps = 6/70 (8%) Query: 269 PATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKG 328 P ++ V+ + V+V G+ KG DV AL LGA+ V + +V K Sbjct: 154 PEVVEGTVRAVKEINKDVKVLCGAGISKGEDVKAALDLGAEGVLLASGVVKA------KN 207 Query: 329 VQDVLEILKE 338 V++ + L + Sbjct: 208 VEEAIRELIK 217 >1EEP-A nrPDB Length = 404 Score = 37.4 bits (85), Expect = 0.010, Method: Composition-based stats. Identities = 56/275 (20%), Positives = 110/275 (40%), Gaps = 34/275 (12%) Query: 58 AETDLSTSVLGQRVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSWATSSIEE 117 +E L T L + +S+ I ++AM + + ++A A + G G++ SIE Sbjct: 27 SEVSLKTQ-LTKNISLNIPFLSSAMDTV--TESQMAIAIA-KEGGIGII---HKNMSIEA 79 Query: 118 VAEAGPEALRW-LQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFK 176 + + + Q I + + ++ + E K D +D N K Sbjct: 80 QRKEIEKVKTYKFQKTINTNGDTNEQ---KPEIFTAKQHLEKSDAYKNAEHKEDFPNACK 136 Query: 177 LPPQLRMKNFETSTLSFSPEENFGDDSGLAAYVAKAI---DPSISWEDIKWLRRL-TSLP 232 L K + +S + + + A+V + S I+ ++++ T P Sbjct: 137 ---DLNNKLRVGAAVSIDIDTIERVEELVKAHVDILVIDSAHGHSTRIIELIKKIKTKYP 193 Query: 233 ---IVAKGILRGDDAREAVKHGLN--------GILVSNHGARQLDGVPAT-IDVLPEIVE 280 ++A I+ + A + + G + G + + R + GV I + ++ E Sbjct: 194 NLDLIAGNIVTKEAALDLISVGADCLKVGIGPGSICT---TRIVAGVGVPQITAICDVYE 250 Query: 281 AVEG-KVEVFLDGGVRKGTDVLKALALGAKAVFVG 314 A + + DGG+R DV+KA+A GA +V +G Sbjct: 251 ACNNTNICIIADGGIRFSGDVVKAIAAGADSVMIG 285 >1UUO-A nrPDB Length = 372 Score = 37.0 bits (84), Expect = 0.013, Method: Composition-based stats. Identities = 29/145 (20%), Positives = 56/145 (38%), Gaps = 15/145 (10%) Query: 213 IDPSISWEDIKWLRRLTSLPIVAKGILRGDDAREAVKHGLNGILVSNHGARQLDGVPA-- 270 I P ++ +D + + + + G++ + + GL G L S G L G P Sbjct: 232 IAPDLTAQDKEDIASVAR-ELGIDGLIVT-NTTVSRPVGLQGALRSETGG--LSGKPLRD 287 Query: 271 -TIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKGV 329 + + E+ +G++ + GGV G D L+ + GA V + +++ Sbjct: 288 LSTQTIREMYALTQGRIPIIGVGGVSSGQDALEKIQAGASLVQLYTALIFLGP------- 340 Query: 330 QDVLEILKEEFRLAMALSGCQNVKV 354 V+ +K E + G V Sbjct: 341 -PVVVRVKRELEALLKERGFTTVTD 364 >5CSS-A nrPDB Length = 226 Score = 36.3 bits (82), Expect = 0.025, Method: Composition-based stats. Identities = 14/50 (28%), Positives = 28/50 (56%), Gaps = 1/50 (2%) Query: 273 DVLPEIVEAVEGK-VEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGL 321 +++ +IV+ EG V + G++ G DV +++ LGA+ + V +V Sbjct: 156 EIIEDIVKIYEGTGTSVLVGAGIKTGEDVRRSIGLGARGILVASGVVKSA 205 Score = 30.9 bits (68), Expect = 1.0, Method: Composition-based stats. Identities = 19/77 (24%), Positives = 36/77 (46%), Gaps = 7/77 (9%) Query: 184 KNFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVA-KGILRGD 242 + +E +++ P + G D ++ + I EDI + T ++ GI G+ Sbjct: 129 REYEPDFIAYEPRDLIGGDVSVSTAKPEII------EDIVKIYEGTGTSVLVGAGIKTGE 182 Query: 243 DAREAVKHGLNGILVSN 259 D R ++ G GILV++ Sbjct: 183 DVRRSIGLGARGILVAS 199 >3R2G-A nrPDB Length = 361 Score = 35.5 bits (80), Expect = 0.033, Method: Composition-based stats. Identities = 14/39 (35%), Positives = 21/39 (53%) Query: 288 VFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGE 326 + DGG++ D++KALA GA V +G + GE Sbjct: 202 IVADGGIKTSGDIVKALAFGADFVMIGGMLAGSAPTPGE 240 >4WY0-A nrPDB Length = 305 Score = 35.5 bits (80), Expect = 0.039, Method: Composition-based stats. Identities = 20/53 (37%), Positives = 25/53 (47%), Gaps = 4/53 (7%) Query: 270 ATIDVLPEIVEAVEGKVEV--FLDGGVRKGTDVLKALALGAKAVFVGRPIVWG 320 A ++VL EI G++ V F GGV D + LGA VFVG I Sbjct: 201 APVEVLREIKRL--GRLPVVNFAAGGVTTPADAALMMHLGADGVFVGSGIFKS 251 Score = 30.1 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 16/53 (30%), Positives = 26/53 (49%), Gaps = 3/53 (5%) Query: 208 YVAKAIDPSISWEDIKWLRRLTSLPIV---AKGILRGDDAREAVKHGLNGILV 257 VA+A E ++ ++RL LP+V A G+ DA + G +G+ V Sbjct: 192 LVAEAKQLGAPVEVLREIKRLGRLPVVNFAAGGVTTPADAALMMHLGADGVFV 244 >2ISS-A nrPDB Length = 313 Score = 35.5 bits (80), Expect = 0.043, Method: Composition-based stats. Identities = 18/56 (32%), Positives = 26/56 (46%), Gaps = 4/56 (7%) Query: 267 GVPATIDVLPEIVEAVEGKVEV--FLDGGVRKGTDVLKALALGAKAVFVGRPIVWG 320 + A +++L E+ G++ V F GGV D + LGA VFVG I Sbjct: 209 EIGAPVELLREVKRL--GRLPVVNFAAGGVATPADAALMMMLGADGVFVGSGIFKS 262 Score = 28.9 bits (63), Expect = 3.4, Method: Composition-based stats. Identities = 13/42 (30%), Positives = 22/42 (52%), Gaps = 3/42 (7%) Query: 219 WEDIKWLRRLTSLPIV---AKGILRGDDAREAVKHGLNGILV 257 E ++ ++RL LP+V A G+ DA + G +G+ V Sbjct: 214 VELLREVKRLGRLPVVNFAAGGVATPADAALMMMLGADGVFV 255 >2NV2-A nrPDB Length = 294 Score = 35.1 bits (79), Expect = 0.053, Method: Composition-based stats. Identities = 19/53 (35%), Positives = 26/53 (49%), Gaps = 4/53 (7%) Query: 270 ATIDVLPEIVEAVEGKVEV--FLDGGVRKGTDVLKALALGAKAVFVGRPIVWG 320 A ++L +I + +GK+ V F GGV D + LGA VFVG I Sbjct: 191 APYELLLQIKK--DGKLPVVNFAAGGVATPADAALMMQLGADGVFVGSGIFKS 241 Score = 28.6 bits (62), Expect = 4.9, Method: Composition-based stats. Identities = 12/53 (22%), Positives = 26/53 (49%), Gaps = 3/53 (5%) Query: 208 YVAKAIDPSISWEDIKWLRRLTSLPIV---AKGILRGDDAREAVKHGLNGILV 257 + +A + +E + +++ LP+V A G+ DA ++ G +G+ V Sbjct: 182 LMTEAKNLGAPYELLLQIKKDGKLPVVNFAAGGVATPADAALMMQLGADGVFV 234 >1VHN-A nrPDB Length = 318 Score = 34.7 bits (78), Expect = 0.069, Method: Composition-based stats. Identities = 24/188 (12%), Positives = 58/188 (30%), Gaps = 29/188 (15%) Query: 177 LPPQLRMKNFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWED-IKWLRRLTSLPIVA 235 L ++ + ++ + + K++ S + + W + Sbjct: 89 LNAGCPVRKVVKEGAGGALLKDLRHFRYIVRELRKSVSGKFSVKTRLGWEKN-------- 140 Query: 236 KGILRGDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVR 295 + R V+ G++ + + Q A L +E ++ F+ G + Sbjct: 141 ---EVEEIYRILVEEGVDEVFIHTRTVVQSFTGRAEWKAL----SVLEKRIPTFVSGDIF 193 Query: 296 KGTDVLKAL-ALGAKAV-----FVGRPIVWG-------LAFQGEKGVQDVLEILKEEFRL 342 D +AL G + +GRP ++ E +++L + L Sbjct: 194 TPEDAKRALEESGCDGLLVARGAIGRPWIFKQIKDFLRSGKYSEPSREEILRTFERHLEL 253 Query: 343 AMALSGCQ 350 + G + Sbjct: 254 LIKTKGER 261 >2GGG-A nrPDB Length = 375 Score = 34.3 bits (77), Expect = 0.075, Method: Composition-based stats. Identities = 30/130 (23%), Positives = 54/130 (41%), Gaps = 10/130 (7%) Query: 131 LYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKLPPQLRMKNFETST 190 L I D + T LVR+ + GY+ I + + G + VR + P +R+ S Sbjct: 143 LGIQADEQATVDLVRRHVEQGYRRIKLKIKP---GWDVQPVRATREAFPDIRLTVDANSA 199 Query: 191 LSFSPEENFGDDSGLAAYVAKAIDPSISWEDI---KWLRRLTSLPIVA-KGILRGDDARE 246 + + L Y I+ ++W+D+ L R P+ + + DAR+ Sbjct: 200 YTLADAGRLRQ---LDEYDLTYIEQPLAWDDLVDHAELARRIRTPLCLDESVASASDARK 256 Query: 247 AVKHGLNGIL 256 A+ G G++ Sbjct: 257 ALALGAGGVI 266 Score = 32.0 bits (71), Expect = 0.44, Method: Composition-based stats. Identities = 23/77 (29%), Positives = 28/77 (36%), Gaps = 8/77 (10%) Query: 243 DAREAVKHGLNGILVSNHGARQLDGVPATI--------DVLPEIVEAVEGKVEVFLDGGV 294 D R V L RQLD T D++ A + + LD V Sbjct: 189 DIRLTVDANSAYTLADAGRLRQLDEYDLTYIEQPLAWDDLVDHAELARRIRTPLCLDESV 248 Query: 295 RKGTDVLKALALGAKAV 311 +D KALALGA V Sbjct: 249 ASASDARKALALGAGGV 265 >5Z9Y-A nrPDB Length = 252 Score = 34.3 bits (77), Expect = 0.084, Method: Composition-based stats. Identities = 28/144 (19%), Positives = 52/144 (36%), Gaps = 35/144 (24%) Query: 128 WLQLYIYKD----REVTKKLVRQAEKM---GYKAIFVTVDTPYLGNRLDDVRNRFKLPPQ 180 W++L + D +LVR AE++ G+ + T D P L RL+D +P Sbjct: 96 WVKLEVIADERTLWPDAVELVRAAEQLVDDGFVVLPYTTDDPVLARRLEDTGCAAVMPLG 155 Query: 181 LRMKNFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVAK-GIL 239 + + +I+ + +P+V GI Sbjct: 156 SPIGTGLGIA---------------------------NPHNIEMIVAGARVPVVLDAGIG 188 Query: 240 RGDDAREAVKHGLNGILVSNHGAR 263 DA A++ G + +L+++ R Sbjct: 189 TASDAALAMELGCDAVLLASAVTR 212 Score = 32.4 bits (72), Expect = 0.34, Method: Composition-based stats. Identities = 32/193 (16%), Positives = 58/193 (30%), Gaps = 19/193 (9%) Query: 130 QLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKLPPQLRMKNFETS 189 Q I E+T +R+ + G + D+ NR + P ++ Sbjct: 32 QALIASGTELTTVAIRRVDADGGTGLL-------------DLLNRLGITPLPNTAGSRSA 78 Query: 190 TLSFSPEENFGDDSGLAAYVAKAI-DPSISWEDIKWLRRLTSLPIVAKGIL----RGDDA 244 + + + + I D W D L + +V G + DD Sbjct: 79 AEAVLTAQLAREALNTNWVKLEVIADERTLWPDAVEL-VRAAEQLVDDGFVVLPYTTDDP 137 Query: 245 REAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKAL 304 A + G + + + +V V LD G+ +D A+ Sbjct: 138 VLARRLEDTGCAAVMPLGSPIGTGLGIANPHNIEMIVAGARVPVVLDAGIGTASDAALAM 197 Query: 305 ALGAKAVFVGRPI 317 LG AV + + Sbjct: 198 ELGCDAVLLASAV 210 >1WX0-A nrPDB Length = 223 Score = 34.0 bits (76), Expect = 0.11, Method: Composition-based stats. Identities = 21/86 (24%), Positives = 34/86 (39%), Gaps = 4/86 (4%) Query: 238 ILRGDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVE-GKVEV-FLDGGVR 295 I + A A + G + VS R D ++L EIVE ++ + V + +R Sbjct: 118 IFSANQALLAARAGAS--YVSPFLGRVDDISWDGGELLREIVEMIQVQDLPVKVIAASIR 175 Query: 296 KGTDVLKALALGAKAVFVGRPIVWGL 321 V +A LGA + + L Sbjct: 176 HPRHVTEAALLGADIATMPHAVFKQL 201 >1TJR-A nrPDB Length = 261 Score = 34.0 bits (76), Expect = 0.11, Method: Composition-based stats. Identities = 13/64 (20%), Positives = 32/64 (50%), Gaps = 1/64 (1%) Query: 222 IKWLRRLTSLPIVAK-GILRGDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVE 280 I+ ++++T+ P+ GI + + ++ + G +G+++ + RQL + L + E Sbjct: 192 IQEVKKVTNKPVAVGFGISKPEHVKQIAQWGADGVIIGSAMVRQLGEAASPKQGLRRLEE 251 Query: 281 AVEG 284 G Sbjct: 252 YARG 255 >3W7D-A nrPDB Length = 313 Score = 34.0 bits (76), Expect = 0.12, Method: Composition-based stats. Identities = 25/101 (24%), Positives = 36/101 (35%), Gaps = 14/101 (13%) Query: 263 RQLDGVPATIDVLPEIVEAVEG---KVE---VFLDGGVRKGTDVLKALALGAKAVFVGRP 316 +Q G +LP + V + VF GGV G D + GA V VG Sbjct: 215 KQGFGGLGGKYILPTALANVNAFYRRCPDKLVFGCGGVYSGEDAFLHILAGASMVQVG-- 272 Query: 317 IVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDK 357 A Q E + L++E MA G + ++ Sbjct: 273 ----TALQEEG--PGIFTRLEDELLEIMARKGYRTLEEFRG 307 >4UTT-A nrPDB Length = 229 Score = 34.0 bits (76), Expect = 0.12, Method: Composition-based stats. Identities = 15/43 (34%), Positives = 25/43 (58%), Gaps = 2/43 (4%) Query: 272 IDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVG 314 ++L E+V+ V K+ V +G + ++ KAL LGA + VG Sbjct: 172 FELLEELVKTV--KIPVICEGRINTPEELKKALDLGAYSAVVG 212 >4N6F-A nrPDB Length = 256 Score = 33.6 bits (75), Expect = 0.14, Method: Composition-based stats. Identities = 23/109 (21%), Positives = 41/109 (37%), Gaps = 8/109 (7%) Query: 214 DPSISWEDIKWLRRLTS--LPIVAKGILRGDDAREAVKHGLNGILVSNHGARQLDGVPAT 271 D + + E + LR LP + + EA L + R + A Sbjct: 121 DNAGTVEAARELRAEGMELLPFILPDLATARALEEAGCAALRVMASPVASGRGIANPAAI 180 Query: 272 IDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWG 320 +++ +I + V ++GG+ V +A+ LGA A V +V Sbjct: 181 RELIEQI------GIPVVVEGGIGSARHVAEAMELGASATLVNTALVRA 223 >1AK5-A nrPDB Length = 503 Score = 33.6 bits (75), Expect = 0.14, Method: Composition-based stats. Identities = 17/51 (33%), Positives = 25/51 (49%), Gaps = 3/51 (5%) Query: 268 VPATIDVLPEIVEAVEGK---VEVFLDGGVRKGTDVLKALALGAKAVFVGR 315 A IDV+ E + E + V DGG+ + ALA+GA + +GR Sbjct: 332 ATAVIDVVAERNKYFEETGIYIPVCSDGGIVYDYHMTLALAMGADFIMLGR 382 >6B8S-A nrPDB Length = 359 Score = 33.6 bits (75), Expect = 0.15, Method: Composition-based stats. Identities = 51/339 (15%), Positives = 114/339 (33%), Gaps = 68/339 (20%) Query: 58 AETDLSTSVLGQRVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSWATSSIEE 117 L +LG P+ + A D + +RA + G G ++ Sbjct: 54 KNPKLENEILGLNFPNPLGLA-------AGFDKNASMLRALIAFGFGY----LEAGTLTN 102 Query: 118 VAEAGPEALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKL 177 A+ G E R R + ++ ++ A MG+ LG R + +K Sbjct: 103 EAQVGNERPRLF-------RHIEEESLQNA--MGFNNY-----GAVLGARSFNRFAPYKT 148 Query: 178 PPQLRM---KNFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISW--EDIKWLRRLTSLP 232 P + + K+ E + + + Y + + D++ + L Sbjct: 149 PIGINLGKNKHIEQAHALEDYKAVLNQCLNIGDYYTFNLSSPNTPNLRDLQNKAFVNELF 208 Query: 233 IVAKGILRG----------------DDAREAVKHGLNGILVSNHG-ARQLDGVPATI--- 272 +AK + + A++ G +GI+ +N + L P + Sbjct: 209 CMAKEMTHKPLFLKIAPDLEIDDMLEIVNSAIEAGAHGIIATNTTIDKSLVFAPKEMGGL 268 Query: 273 ----------DVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLA 322 +V E+ +A K + GG+ + + + +GA + + ++ Sbjct: 269 SGKCLTKKSREVFKELAKAFFNKSVLVSVGGISDAKEAYERIKMGASLLQIYSAFIYNGP 328 Query: 323 FQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDKTLVR 361 + ++D++++L+++ G +VK +R Sbjct: 329 NLCQNILKDLVKLLQKD--------GFLSVKEAIGADLR 359 >3T55-A nrPDB Length = 272 Score = 33.2 bits (74), Expect = 0.21, Method: Composition-based stats. Identities = 23/77 (29%), Positives = 31/77 (40%), Gaps = 3/77 (3%) Query: 238 ILRGDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKG 297 + +A A+K G I V+ AR L + D I + V + GVR Sbjct: 169 VHTEQEADRALKAGAKVIGVN---ARDLMTLDVDRDCFARIAPGLPSSVIRIAESGVRGT 225 Query: 298 TDVLKALALGAKAVFVG 314 D+L GA AV VG Sbjct: 226 ADLLAYAGAGADAVLVG 242 >1WV2-A nrPDB Length = 265 Score = 32.8 bits (73), Expect = 0.23, Method: Composition-based stats. Identities = 14/38 (36%), Positives = 19/38 (50%) Query: 283 EGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWG 320 E KV V +D GV +D A+ LG +AV + I Sbjct: 185 EAKVPVLVDAGVGTASDAAIAMELGCEAVLMNTAIAHA 222 >2IHN-A nrPDB Length = 305 Score = 32.8 bits (73), Expect = 0.23, Method: Composition-based stats. Identities = 21/123 (17%), Positives = 38/123 (30%), Gaps = 26/123 (21%) Query: 144 VRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKLPPQLRMKNFETSTLSFSPEENFGDDS 203 V++A+ +GY I + +D G D + + EE+ D Sbjct: 55 VKKAKTLGYTKIVLCIDNAKSGYWRRD------------FAYYYKKNRGKAREESTWDWE 102 Query: 204 GLAAYVAKAIDP-----SISWEDIKWLRRLTSLPIVAKGILRGDDAREAVKHGLNGILVS 258 G K ID DI + ++ K + G +++S Sbjct: 103 GYFESSHKVIDELKAYMPYIVMDIDKYEANDHIAVLVK---------KFSLEGHKILIIS 153 Query: 259 NHG 261 + G Sbjct: 154 SDG 156 >1HG3-A nrPDB Length = 225 Score = 32.8 bits (73), Expect = 0.23, Method: Composition-based stats. Identities = 14/44 (31%), Positives = 22/44 (50%) Query: 277 EIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWG 320 E+V+ V +V+V G+ G DV KA+ LG V + + Sbjct: 168 ELVKKVNPEVKVLCGAGISTGEDVKKAIELGTVGVLLASGVTKA 211 >4WZH-A nrPDB Length = 347 Score = 32.4 bits (72), Expect = 0.28, Method: Composition-based stats. Identities = 19/70 (27%), Positives = 24/70 (34%), Gaps = 8/70 (11%) Query: 288 VFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALS 347 +F GGV G D + GA V VG A E + E L E MA Sbjct: 280 IFGCGGVYTGEDAFLHVLAGASMVQVG------TALHEEGAA--IFERLTAELLDVMAKK 331 Query: 348 GCQNVKVIDK 357 G + + Sbjct: 332 GYKALDEFRG 341 >2C6Q-A nrPDB Length = 351 Score = 32.4 bits (72), Expect = 0.33, Method: Composition-based stats. Identities = 25/117 (21%), Positives = 45/117 (38%), Gaps = 13/117 (11%) Query: 219 WEDIKWLRRLTSLPIVAKGILRGDDAREAVKHGLN--------GILVSNHGARQLDGVPA 270 +D++ +R I+A ++ G+ E + G + G + + ++ Sbjct: 152 VKDVR--KRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTTR--KKTGVGYP 207 Query: 271 TIDVLPEIVEAVEG-KVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGE 326 + + E +A G K + DGG DV KA GA V +G + GE Sbjct: 208 QLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGE 264 >4ADT-A nrPDB Length = 297 Score = 32.0 bits (71), Expect = 0.38, Method: Composition-based stats. Identities = 14/48 (29%), Positives = 22/48 (45%), Gaps = 4/48 (8%) Query: 269 PATIDVLPEIVEAVEGKVEV--FLDGGVRKGTDVLKALALGAKAVFVG 314 A ID++ ++ ++ V F GG+ D + LG VFVG Sbjct: 193 RAPIDLI--LLTRKLKRLPVVNFAAGGIATPADAAMCMQLGMDGVFVG 238 >2YZR-A nrPDB Length = 330 Score = 32.0 bits (71), Expect = 0.39, Method: Composition-based stats. Identities = 19/53 (35%), Positives = 26/53 (49%), Gaps = 4/53 (7%) Query: 272 IDVLPEIVEAVE--GKVEV--FLDGGVRKGTDVLKALALGAKAVFVGRPIVWG 320 ID L E++ V+ G++ V F GGV D + LG+ VFVG I Sbjct: 225 IDGLYEVLLEVKKLGRLPVVNFAAGGVATPADAALMMQLGSDGVFVGSGIFKS 277 >2Y88-A nrPDB Length = 244 Score = 32.0 bits (71), Expect = 0.42, Method: Composition-based stats. Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 6/60 (10%) Query: 273 DVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIV----WGLAFQGEKG 328 ++L E+V ++ +VE L GG+R + ALA G V VG + W GE G Sbjct: 64 ELLAEVVGKLDVQVE--LSGGIRDDESLAAALATGCARVNVGTAALENPQWCARVIGEHG 121 >4FIQ-A nrPDB Length = 335 Score = 32.0 bits (71), Expect = 0.43, Method: Composition-based stats. Identities = 14/39 (35%), Positives = 18/39 (46%), Gaps = 2/39 (5%) Query: 284 GKVEV--FLDGGVRKGTDVLKALALGAKAVFVGRPIVWG 320 G++ V F GGV D +A+G VFVG I Sbjct: 246 GRLPVVNFAAGGVATPADAALMMAMGMDGVFVGSGIFKS 284 >1B0U-A nrPDB Length = 262 Score = 32.0 bits (71), Expect = 0.45, Method: Composition-based stats. Identities = 27/153 (17%), Positives = 48/153 (31%), Gaps = 26/153 (16%) Query: 185 NFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVAKGILRGDDA 244 N + L + W + L + PI G+ + D Sbjct: 71 NLVRDKDGQLKVADKNQLRLLRTRLTMVFQHFNLWSHMTVLENVMEAPIQVLGLSKHDAR 130 Query: 245 REAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKAL 304 A+K ++ G I E +GK V L GG ++ + +AL Sbjct: 131 ERALK------YLAKVG----------------IDERAQGKYPVHLSGGQQQRVSIARAL 168 Query: 305 ALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILK 337 A+ + P + + V +VL I++ Sbjct: 169 AMEPDVLLFDEPT----SALDPELVGEVLRIMQ 197 >1MZH-A nrPDB Length = 225 Score = 31.6 bits (70), Expect = 0.50, Method: Composition-based stats. Identities = 28/184 (15%), Positives = 61/184 (33%), Gaps = 16/184 (8%) Query: 141 KKLVRQAEKMGYKAIFVT---VDTPYLGNRLDDVRNRFKLPPQLRMKNF-ETSTLSFSPE 196 ++ V ++E++G A+ V V + V P L + + + Sbjct: 23 EEFVLKSEELGIYAVCVNPYHVKLASSIAKKVKVCCVIGFPLGLNKTSVKVKEAVEAVRD 82 Query: 197 ENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVAKGILRG--------DDAREAV 248 D K+ E++K + R T + + + Sbjct: 83 GAQELDIVWNLSAFKSEKYDFVVEELKEIFRETPSAVHKVIVETPYLNEEEIKKAVEICI 142 Query: 249 KHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGA 308 + G + I S A + T++ + I + +G+++V GG+R + + GA Sbjct: 143 EAGADFIKTSTGFAPR----GTTLEEVRLIKSSAKGRIKVKASGGIRDLETAISMIEAGA 198 Query: 309 KAVF 312 + Sbjct: 199 DRIG 202 >1UB3-A nrPDB Length = 220 Score = 31.6 bits (70), Expect = 0.50, Method: Composition-based stats. Identities = 28/177 (15%), Positives = 61/177 (34%), Gaps = 22/177 (12%) Query: 171 VRNRFKLPPQLRMKNFETSTLSFSPEENFGDDSGLAAY-----------VAKAIDPSISW 219 VR R+ P R+ L + +E ++ LA + +A + + Sbjct: 46 VRARYPHAPF-RLVTVVGFPLGYQEKEVKALEAALACARGADEVDMVLHLGRAKAGDLDY 104 Query: 220 EDIKWLRRLTSLP------IVAKGILRGDDAREAVKHGLNGILVSNHGARQLDGVP--AT 271 + + ++P I+ G ++ + + G ++ P A+ Sbjct: 105 LEAEVRAVREAVPQAVLKVILETGYFSPEEIARLAEAAIRGG--ADFLKTSTGFGPRGAS 162 Query: 272 IDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKG 328 ++ + +V +G+ +V GG+R L+ L GA + + G G Sbjct: 163 LEDVALLVRVAQGRAQVKAAGGIRDRETALRMLKAGASRLGTSSGVALVAGEGGTLG 219 >6MFM-A nrPDB Length = 313 Score = 31.6 bits (70), Expect = 0.58, Method: Composition-based stats. Identities = 34/202 (16%), Positives = 74/202 (36%), Gaps = 6/202 (2%) Query: 149 KMGYKAIFVTV-DTPYLGNRLDDVRNRFKLPPQLRMKNFETSTLSFSPEENFGDDSGLAA 207 +G+K++ V + D +G + + LP Q+ + E + N + + Sbjct: 67 AIGWKSVAVNLSDIAAMGAKPHSILLAISLP-QVDHEWLEGFSQGIYDCCNQFGVALIGG 125 Query: 208 YVAKAIDPSISWEDIKWLRRLTSLPIVAKGILRGDDAREAVKHG--LNGILVSNHGARQL 265 + +I+ + W+ T ++ G GD + + G G+ H +Q Sbjct: 126 DTTQGPHLTITVTAMGWIE--TGKAVLRSGAKVGDYVCVSGQIGDAAYGLQHLGHSLQQR 183 Query: 266 DGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQG 325 P L E ++ + + DG + +LKA +GA+ + P+ L Sbjct: 184 LDYPTPRCKLGEELKGLASSMIDVSDGLAQDLGHILKASKVGARLILEKLPVDPVLQQIE 243 Query: 326 EKGVQDVLEILKEEFRLAMALS 347 E+ +++ L ++ Sbjct: 244 EQQRWQYALAGGDDYELCFTIT 265 >5XFW-A nrPDB Length = 334 Score = 31.6 bits (70), Expect = 0.61, Method: Composition-based stats. Identities = 23/101 (22%), Positives = 34/101 (33%), Gaps = 14/101 (13%) Query: 263 RQLDGVPATIDVLPEIVEAVEG---KVE---VFLDGGVRKGTDVLKALALGAKAVFVGRP 316 +Q G VLP + V + VF GGV G + + GA V VG Sbjct: 236 KQGFGGLGGKYVLPTALANVNAFFRRCPDKLVFGCGGVYSGEEAFLHILAGASMVQVG-- 293 Query: 317 IVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDK 357 A E + + L +E + M G + + Sbjct: 294 ----TALHDEGPI--IFARLNKELQEIMTNKGYKTLDEFRG 328 >5ZKN-A nrPDB Length = 241 Score = 31.3 bits (69), Expect = 0.64, Method: Composition-based stats. Identities = 23/94 (24%), Positives = 36/94 (38%), Gaps = 4/94 (4%) Query: 222 IKWLRRLTSLPIVAKGILRGDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEA 281 I ++ + I D+A A K G + +V D L E+ + Sbjct: 133 IAEIKEKYPNQLFMADISSVDEALYAEKIGFD--IVGTTLVGYTDYTK-NYKALEELKKV 189 Query: 282 VEGK-VEVFLDGGVRKGTDVLKALALGAKAVFVG 314 V+ + V +G + KAL +GA AV VG Sbjct: 190 VKVVKIPVIAEGNIDTPLKAKKALEIGAFAVVVG 223 >5UE9-A nrPDB Length = 306 Score = 30.9 bits (68), Expect = 0.88, Method: Composition-based stats. Identities = 14/46 (30%), Positives = 23/46 (50%), Gaps = 2/46 (4%) Query: 269 PATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVG 314 P + ++ ++ + V + + GGV DVL+ GA AV VG Sbjct: 223 PVALKLIHQVAQVV--DIPIIGMGGVESAQDVLEMYMAGASAVAVG 266 >2BWG-A nrPDB Length = 367 Score = 30.9 bits (68), Expect = 0.92, Method: Composition-based stats. Identities = 30/116 (25%), Positives = 44/116 (37%), Gaps = 8/116 (6%) Query: 219 WEDIKWLRRLTS-LPIVAKGILRGDDAREAVKHGLNGILV-----SNHGARQLDGVPAT- 271 E +K +R I+A ++ G+ E + G + I V S R GV Sbjct: 161 VEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQ 220 Query: 272 IDVLPEIVEAVEG-KVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGE 326 + + E ++ G K + DGG DV KA GA V +G GE Sbjct: 221 LSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMFSGHTECAGE 276 >3GZ3-A nrPDB Length = 354 Score = 30.9 bits (68), Expect = 0.96, Method: Composition-based stats. Identities = 25/97 (25%), Positives = 33/97 (34%), Gaps = 11/97 (11%) Query: 261 GARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWG 320 G R +P + + GK+ +F GGV G D + GA V VG Sbjct: 256 GGR--YVLPTALANINAFYRRCPGKL-IFGCGGVYTGEDAFLHVLAGASMVQVG------ 306 Query: 321 LAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDK 357 A Q E + E L E MA Q + Sbjct: 307 TALQEEG--PSIFERLTSELLGVMAKKRYQTLDEFRG 341 >1XI3-A nrPDB Length = 215 Score = 30.5 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 36/165 (21%), Positives = 71/165 (43%), Gaps = 26/165 (15%) Query: 115 IEEVAEAGPEALRWLQLY--------IYKDREVTKKLVRQAEKMGYK------AIFVTVD 160 +E V EA +Q+ +Y+ + ++L R+ + + + A+ V D Sbjct: 29 VESVREALEGGATAIQMRIKNAPTREMYEIGKTLRQLTREYDALFFVDDRVDVALAVDAD 88 Query: 161 TPYLGNRLDDVRNRFKLPPQLRMKNFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWE 220 LG + ++ P L +++ E + G A ++ P+ + E Sbjct: 89 GVQLGPEDMPIEVAKEIAPNL----IIGASVYSLEEALEAEKKGADYLGAGSVFPTKTKE 144 Query: 221 D-----IKWLRRLT---SLPIVAKGILRGDDAREAVKHGLNGILV 257 D ++ LR++ +P+VA G + D+ARE +K G++GI V Sbjct: 145 DARVIGLEGLRKIVESVKIPVVAIGGINKDNAREVLKTGVDGIAV 189 >3L5A-A nrPDB Length = 419 Score = 30.5 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 11/41 (26%), Positives = 18/41 (43%), Gaps = 1/41 (2%) Query: 278 IVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIV 318 + E + G++ + GG+ L AL A V + P V Sbjct: 311 VYEHLAGRIPLIASGGINSPESALDALQ-HADMVGMSSPFV 350 >1N7K-A nrPDB Length = 234 Score = 30.5 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 43/223 (19%), Positives = 83/223 (37%), Gaps = 33/223 (14%) Query: 114 SIEEVAEAGPEALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRN 173 S E++A L L E + LVR+A G++ +T P ++ + Sbjct: 16 SPEDLASRIDSTL----LSPRATEEDVRNLVREASDYGFRCAVLT---PVYTVKISGLAE 68 Query: 174 RFKLPPQLRMKNFETSTLSFSP-EENFGDDSGLAAYVAKAID----PSISWEDI-KWLRR 227 + +++ + L +P E + + A +D S+ E + + + Sbjct: 69 KL----GVKLCSVIGFPLGQAPLEVKLVEAQTVLEAGATELDVVPHLSLGPEAVYREVSG 124 Query: 228 LTSLP----IVAKGILRG---DD------AREAVKHGLNGILVSNHGARQLDGVPATIDV 274 + L V K IL DD + + G + I+ ++ G G P T+ Sbjct: 125 IVKLAKSYGAVVKVILEAPLWDDKTLSLLVDSSRRAGAD-IVKTSTGVYTKGGDPVTVFR 183 Query: 275 LPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPI 317 L + + + + V GG+R G D + A+ GA + + Sbjct: 184 LASLAKPL--GMGVKASGGIRSGIDAVLAVGAGADIIGTSSAV 224 >2ZBT-A nrPDB Length = 297 Score = 30.5 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 27/154 (17%), Positives = 46/154 (29%), Gaps = 35/154 (22%) Query: 172 RNRFKLPPQLRMKNFETSTLSFSPEENFGDDSGLAA---YVAKAIDPSISWEDIKWLRRL 228 + +FK+P +N + + G A V W++I++++ L Sbjct: 121 KWKFKVPFVCGARNLGEALRRIAEGAAMIRTKGEAGTGNVVEAVRHARTMWKEIRYVQSL 180 Query: 229 TSLPIVAKGILRGDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEV 288 ++A G V +HG ++ V Sbjct: 181 REDELMAYAKEIGAPFELVK-------WVHDHG-----------------------RLPV 210 Query: 289 --FLDGGVRKGTDVLKALALGAKAVFVGRPIVWG 320 F GG+ D + LG VFVG I Sbjct: 211 VNFAAGGIATPADAALMMHLGMDGVFVGSGIFKS 244 >1YQX-A nrPDB Length = 366 Score = 30.5 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 31/135 (22%), Positives = 52/135 (38%), Gaps = 17/135 (12%) Query: 251 GLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVF----LDGGVRKGTDVLKALAL 306 G + LVS Q+ T+D + + V AV + +F G + K L L Sbjct: 232 GADSFLVSRD-QEQMQAAAGTLDGIIDTVSAVHPLLPLFGLLKSHGKLILVGAPEKPLEL 290 Query: 307 GAKAVFVGRPIVWGLAFQGEKGVQDVLEI-----LKEEFRLAMALSGCQNVKVIDKTLVR 361 A ++ GR IV G G K Q++++ + + + ++ + K VR Sbjct: 291 PAFSLIAGRKIVAGSGIGGMKETQEMIDFAAKHNITADIEVISTDYLNTAMERLAKNDVR 350 Query: 362 -------KNPLAVSK 369 N LA +K Sbjct: 351 YRFVIDVGNTLAATK 365 >1OI7-A nrPDB Length = 288 Score = 30.1 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 23/108 (21%), Positives = 38/108 (35%), Gaps = 9/108 (8%) Query: 186 FETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVAKGILRGDDAR 245 +T D A + I S E W++ P+V G + G A Sbjct: 182 VIGTTFKDLLPLFNEDPETEAVVLIGEIGGSDEEEAAAWVKDHMKKPVV--GFIGGRSAP 239 Query: 246 EAVKHGLNG-ILVSNHGARQ------LDGVPATIDVLPEIVEAVEGKV 286 + + G G I++ N G + + D + EIVE V+ + Sbjct: 240 KGKRMGHAGAIIMGNVGTPESKLRAFAEAGIPVADTIDEIVELVKKAL 287 >3THA-A nrPDB Length = 252 Score = 30.1 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 25/126 (19%), Positives = 50/126 (39%), Gaps = 14/126 (11%) Query: 141 KKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKLPPQLRMKNFETSTLSFSPEENFG 200 +K V++A+ +G A+ V P L D + + + + T + Sbjct: 106 EKFVKKAKSLGICALIV----PELSFEESDDLIKECERYNIALITLVSVTTPKERVKKLV 161 Query: 201 DDSGLAAYV--------AKAIDPSISWEDIKWLRRLTSLPIVAK-GILRGDDAREAVKHG 251 + Y+ K+++ +I + +K +R T+LPI GI D + K Sbjct: 162 KHAKGFIYLLASIGITGTKSVEEAILQDKVKEIRSFTNLPIFVGFGIQNNQDVKRMRKV- 220 Query: 252 LNGILV 257 +G++V Sbjct: 221 ADGVIV 226 >1F76-A nrPDB Length = 336 Score = 30.1 bits (66), Expect = 1.8, Method: Composition-based stats. Identities = 14/93 (15%), Positives = 36/93 (38%), Gaps = 17/93 (18%) Query: 244 AREAVKHGLNGILVSN--------HGARQLDGVPA---------TIDVLPEIVEAVEGKV 286 A V+H ++G++ +N G + D + +++ + + G++ Sbjct: 231 ADSLVRHNIDGVIATNTTLDRSLVQGMKNCDQTGGLSGRPLQLKSTEIIRRLSLELNGRL 290 Query: 287 EVFLDGGVRKGTDVLKALALGAKAVFVGRPIVW 319 + GG+ + +A GA V + ++ Sbjct: 291 PIIGVGGIDSVIAAREKIAAGASLVQIYSGFIF 323 >5K8C-A nrPDB Length = 358 Score = 29.7 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 19/45 (42%), Positives = 26/45 (57%), Gaps = 3/45 (6%) Query: 265 LDGVPATI--DVLPEIVEAVEGKVEVFLDG-GVRKGTDVLKALAL 306 +D P+TI D L E V+A GK+ V + G G DV KA++L Sbjct: 69 VDEEPSTIQIDALTEQVQAFNGKLPVSVVGLGGGSTMDVAKAVSL 113 >2VEP-A nrPDB Length = 244 Score = 29.7 bits (65), Expect = 2.4, Method: Composition-based stats. Identities = 22/71 (30%), Positives = 32/71 (45%), Gaps = 9/71 (12%) Query: 265 LDGVPATID---VLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIV--- 318 LD T D ++ E+ +A++ KVE L GG+R + ALA G V +G + Sbjct: 54 LDAAFGTGDNRALIAEVAQAMDIKVE--LSGGIRDDDTLAAALATGCTRVNLGTAALETP 111 Query: 319 -WGLAFQGEKG 328 W E G Sbjct: 112 EWVAKVIAEHG 122 >4JEJ-A nrPDB Length = 244 Score = 29.3 bits (64), Expect = 2.7, Method: Composition-based stats. Identities = 12/49 (24%), Positives = 23/49 (46%), Gaps = 2/49 (4%) Query: 269 PATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPI 317 P ++++ I + VE + + + GG+ + KA GA V +G Sbjct: 188 PVPLEMISVISQNVE--IPIIVGGGIVDLHGIKKAYNAGADLVVIGTAF 234 >1H5Y-A nrPDB Length = 253 Score = 29.3 bits (64), Expect = 2.7, Method: Composition-based stats. Identities = 26/95 (27%), Positives = 36/95 (37%), Gaps = 14/95 (14%) Query: 229 TSLPIVAKGI------LRGDDAREAV---KHGLNGILVSNHGARQLDGVPATI-DVLPEI 278 +V KG+ GD AV + G + I + + A AT D + + Sbjct: 15 GGAKVVVKGVNFQGIREVGDPVEMAVRYEEEGADEIAILDITA--APEGRATFIDSVKRV 72 Query: 279 VEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFV 313 EAV + V + GGVR D GA V V Sbjct: 73 AEAVS--IPVLVGGGVRSLEDATTLFRAGADKVSV 105 >4MM1-A nrPDB Length = 250 Score = 29.3 bits (64), Expect = 3.0, Method: Composition-based stats. Identities = 13/53 (24%), Positives = 23/53 (43%), Gaps = 3/53 (5%) Query: 265 LDGVPATIDVLPEIVEAVEGKVE---VFLDGGVRKGTDVLKALALGAKAVFVG 314 L+ + +PE + A+ + + + GG+R G D + GA V G Sbjct: 173 LEAGSGAPEHVPEEMIALVKRCTDQILIVGGGIRSGEDAARVAGAGADVVVTG 225 >1KA9-F nrPDB Length = 252 Score = 28.9 bits (63), Expect = 3.3, Method: Composition-based stats. Identities = 14/42 (33%), Positives = 21/42 (50%), Gaps = 2/42 (4%) Query: 274 VLPEIVEAVEGK--VEVFLDGGVRKGTDVLKALALGAKAVFV 313 +L ++V V + + + + GGVR D K L GA V V Sbjct: 62 ILLDVVARVAERVFIPLTVGGGVRSLEDARKLLLSGADKVSV 103 >5G1T-A nrPDB Length = 256 Score = 28.9 bits (63), Expect = 3.6, Method: Composition-based stats. Identities = 17/55 (30%), Positives = 22/55 (40%), Gaps = 2/55 (3%) Query: 266 DGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWG 320 D I ++ +V V V V + GGVR DV L G V +G V Sbjct: 59 DPAKRQIPLIKTLVAGVN--VPVQVGGGVRTEEDVAALLKAGVARVVIGSTAVKS 111 >3PB0-A nrPDB Length = 300 Score = 28.9 bits (63), Expect = 3.6, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 31/81 (38%), Gaps = 7/81 (8%) Query: 274 VLPEIVEAVEGKVEVFLDGGVRKGTDVLK----ALALGAKAVFVGRPIVWGLAFQGEKGV 329 ++ +E V+GK+ V + G LK A LGA V V P ++G+ Sbjct: 64 LVSRTLEIVDGKIPVIVGAGTNSTEKTLKLVKQAEKLGANGVLVVTPYYNKPT---QEGL 120 Query: 330 QDVLEILKEEFRLAMALSGCQ 350 + + E L + + Sbjct: 121 YQHYKYISERTDLGIVVYNVP 141 >4AXK-A nrPDB Length = 250 Score = 28.9 bits (63), Expect = 3.6, Method: Composition-based stats. Identities = 16/46 (34%), Positives = 26/46 (56%), Gaps = 2/46 (4%) Query: 273 DVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIV 318 +++ EI ++ KVE L GG+R + +ALA GA V +G + Sbjct: 64 ELMAEITRQLDIKVE--LTGGIRDDASLERALATGATRVNIGTAAL 107 >4X2R-A nrPDB Length = 250 Score = 28.6 bits (62), Expect = 4.1, Method: Composition-based stats. Identities = 28/91 (30%), Positives = 39/91 (42%), Gaps = 8/91 (8%) Query: 242 DDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVL 301 + AR+ V+ G I + + A G A + L IV V KVE L GG+R + Sbjct: 37 EAARDWVEAGAEWIHLVDLDAAFGRGSNAPL--LERIVGEVGIKVE--LSGGIRDDASLT 92 Query: 302 KALALGAKAVFVGRPIV----WGLAFQGEKG 328 +AL GA V +G + W E G Sbjct: 93 RALKAGAARVNLGTAALEDPQWTARVIAEHG 123 >6NKE-A nrPDB Length = 252 Score = 28.6 bits (62), Expect = 4.2, Method: Composition-based stats. Identities = 15/79 (18%), Positives = 29/79 (36%), Gaps = 8/79 (10%) Query: 267 GVPATIDVLPEIVEAVEGKV--EVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQ 324 G A V + + V+ K+ + + GG+R ++ GA + V G + Sbjct: 174 GSGAPRPVSEDTISYVKSKINIPLIVGGGIRDPETAMRIALAGADMI------VTGSIAE 227 Query: 325 GEKGVQDVLEILKEEFRLA 343 V VL + + + Sbjct: 228 KSNNVYSVLRNIIGKIKSI 246 >2JS7-A nrPDB Length = 160 Score = 28.6 bits (62), Expect = 4.2, Method: Composition-based stats. Identities = 10/52 (19%), Positives = 22/52 (42%) Query: 113 SSIEEVAEAGPEALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYL 164 +++++ PE Y D + ++++RQ E+ Y+ D L Sbjct: 4 TTLDDPLGHMPERFDAFICYCPSDIQFVQEMIRQLEQTNYRLKLCVSDRDVL 55 >1P9H-A nrPDB Length = 226 Score = 28.2 bits (61), Expect = 6.0, Method: Composition-based stats. Identities = 13/36 (36%), Positives = 18/36 (50%) Query: 226 RRLTSLPIVAKGILRGDDAREAVKHGLNGILVSNHG 261 R TS VA G DA+ +V G + + +NHG Sbjct: 118 RASTSDTGVAVGFNSKADAKNSVAIGHSSHVAANHG 153 >4WQ4-C nrPDB Length = 237 Score = 27.8 bits (60), Expect = 7.2, Method: Composition-based stats. Identities = 14/46 (30%), Positives = 21/46 (45%), Gaps = 2/46 (4%) Query: 293 GVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGE--KGVQDVLEIL 336 GVR G + + LALGA+ +G + +A G VL + Sbjct: 70 GVRIGIGIAQGLALGAELPMIGVSTLMTMAQGAWRKNGATRVLAAI 115 >2XZ9-A nrPDB Length = 324 Score = 27.8 bits (60), Expect = 7.6, Method: Composition-based stats. Identities = 11/29 (37%), Positives = 14/29 (48%) Query: 288 VFLDGGVRKGTDVLKALALGAKAVFVGRP 316 V L + DV ALA GA+ V + R Sbjct: 20 VMLAANIGTPKDVASALANGAEGVGLFRT 48 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.128 0.312 Lambda K H 0.267 0.0388 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,023,691 Number of Sequences: 36641 Number of extensions: 435152 Number of successful extensions: 1895 Number of sequences better than 10.0: 114 Number of HSP's better than 10.0 without gapping: 132 Number of HSP's successfully gapped in prelim test: 56 Number of HSP's that attempted gapping in prelim test: 1668 Number of HSP's gapped (non-prelim): 222 length of query: 370 length of database: 10,336,785 effective HSP length: 98 effective length of query: 272 effective length of database: 6,745,967 effective search space: 1834903024 effective search space used: 1834903024 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 60 (27.8 bits)