BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9UI17 (866 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5L46-A nrPDB 1731 0.0 4P9S-A nrPDB 1597 0.0 1PJ5-A nrPDB 352 3e-97 1YX2-A nrPDB 165 6e-41 1WOR-A nrPDB 158 9e-39 1V5V-A nrPDB 123 4e-28 1VRQ-A nrPDB 120 2e-27 2GAG-A nrPDB 118 1e-26 1WSR-A nrPDB 95 1e-19 3A8J-A nrPDB 91 3e-18 3GIR-A nrPDB 81 2e-15 2GAG-B nrPDB 78 1e-14 3TFJ-A nrPDB 72 1e-12 4YSH-A nrPDB 70 5e-12 1NG3-A nrPDB 64 4e-10 3SM8-A nrPDB 60 5e-09 3AD9-B nrPDB 59 9e-09 1ZOV-A nrPDB 45 2e-04 3BHF-A nrPDB 42 0.001 2UZZ-A nrPDB 41 0.002 2GAH-C nrPDB 40 0.005 1KNR-A nrPDB 35 0.17 4IV9-A nrPDB 35 0.18 3BIQ-A nrPDB 34 0.26 4C5O-A nrPDB 34 0.30 5KXJ-A nrPDB 33 0.37 1VRQ-C nrPDB 33 0.40 3S2F-A nrPDB 33 0.58 6QZO-A nrPDB 33 0.68 3L1R-A nrPDB 33 0.70 5MOG-A nrPDB 33 0.73 2JB2-A nrPDB 32 0.81 3KVE-A nrPDB 32 1.0 5V0C-Z nrPDB 32 1.1 3ATQ-A nrPDB 32 1.3 2VVL-G nrPDB 32 1.7 3RHA-A nrPDB 31 1.8 4IVM-B nrPDB 31 1.9 4UIR-A nrPDB 31 1.9 1F8S-A nrPDB 31 2.1 1L1N-A nrPDB 31 2.3 4K28-A nrPDB 31 2.6 2IUF-A nrPDB 31 2.6 3RHC-A nrPDB 30 3.3 3R9U-A nrPDB 30 3.7 2IVE-A nrPDB 30 3.7 4Y4M-A nrPDB 30 3.9 3UP5-A nrPDB 30 5.1 1RP0-A nrPDB 30 5.2 5JMD-A nrPDB 30 5.6 2CVJ-A nrPDB 30 5.7 3RO8-A nrPDB 30 5.9 2GEY-A nrPDB 30 6.0 3FZA-A nrPDB 30 6.6 1REO-A nrPDB 30 6.6 3LOV-A nrPDB 29 7.0 3ISH-A nrPDB 29 8.3 4ND4-A nrPDB 29 9.2 >5L46-A nrPDB Length = 841 Score = 1731 bits (4483), Expect = 0.0, Method: Compositional matrix adjust. Identities = 837/838 (99%), Positives = 837/838 (99%) Query: 29 VCGREGEEKPPLSAETQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGS 88 VCGREGEEKPPLSAETQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGS Sbjct: 2 VCGREGEEKPPLSAETQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGS 61 Query: 89 TWHAAGLTTYFHPGINLKKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFK 148 TWHAAGLTTYFHPGINLKKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFK Sbjct: 62 TWHAAGLTTYFHPGINLKKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFK 121 Query: 149 YQMTRTGWHATEQYLIEPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARK 208 YQMTRTGWHATEQYLIEPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARK Sbjct: 122 YQMTRTGWHATEQYLIEPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARK 181 Query: 209 CGALLKYPAPVTSLKARSDGTWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPV 268 CGALLKYPAPVTSLKARSDGTWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPV Sbjct: 182 CGALLKYPAPVTSLKARSDGTWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPV 241 Query: 269 QHQYVVTSTISEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNG 328 QHQYVVTSTI EVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNG Sbjct: 242 QHQYVVTSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNG 301 Query: 329 VPPGFGKELFESDLDRIMEHIKAAMEMVPVLKKADIINVVNGPITYSPDILPMVGPHQGV 388 VPPGFGKELFESDLDRIMEHIKAAMEMVPVLKKADIINVVNGPITYSPDILPMVGPHQGV Sbjct: 302 VPPGFGKELFESDLDRIMEHIKAAMEMVPVLKKADIINVVNGPITYSPDILPMVGPHQGV 361 Query: 389 RNYWVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARES 448 RNYWVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARES Sbjct: 362 RNYWVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARES 421 Query: 449 YGFNNIVGYPKEERFAGRPTQRVSGLYQRLESKCSMGFHAGWEQPHWFYKPGQDTQYRPS 508 YGFNNIVGYPKEERFAGRPTQRVSGLYQRLESKCSMGFHAGWEQPHWFYKPGQDTQYRPS Sbjct: 422 YGFNNIVGYPKEERFAGRPTQRVSGLYQRLESKCSMGFHAGWEQPHWFYKPGQDTQYRPS 481 Query: 509 FRRTNWFEPVGSEYKQVMQRVAVTDLSPFGKFNIKGQDSIRLLDHLFANVIPKVGFTNIS 568 FRRTNWFEPVGSEYKQVMQRVAVTDLSPFGKFNIKGQDSIRLLDHLFANVIPKVGFTNIS Sbjct: 482 FRRTNWFEPVGSEYKQVMQRVAVTDLSPFGKFNIKGQDSIRLLDHLFANVIPKVGFTNIS 541 Query: 569 HMLTPKGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEEAVKGGYDVEIKNITDELG 628 HMLTPKGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEEAVKGGYDVEIKNITDELG Sbjct: 542 HMLTPKGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEEAVKGGYDVEIKNITDELG 601 Query: 629 VLGVAGPQARKVLQKLTSEDLSDDVFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHRR 688 VLGVAGPQARKVLQKLTSEDLSDDVFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHRR Sbjct: 602 VLGVAGPQARKVLQKLTSEDLSDDVFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHRR 661 Query: 689 EDSVALYDAIMNAGQEEGIDNFGTYAMNALRLEKAFRAWGLEMNCDTNPLEAGLEYFVKL 748 EDSVALYDAIMNAGQEEGIDNFGTYAMNALRLEKAFRAWGLEMNCDTNPLEAGLEYFVKL Sbjct: 662 EDSVALYDAIMNAGQEEGIDNFGTYAMNALRLEKAFRAWGLEMNCDTNPLEAGLEYFVKL 721 Query: 749 NKPADFIGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESIWYNGKVVGNTTSGSYSYS 808 NKPADFIGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESIWYNGKVVGNTTSGSYSYS Sbjct: 722 NKPADFIGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESIWYNGKVVGNTTSGSYSYS 781 Query: 809 IQKSLAFAYVPVQLSEVGQQVEVELLGKNYPAVIIQEPLVLTEPTRNRLQKKGGKDKT 866 IQKSLAFAYVPVQLSEVGQQVEVELLGKNYPAVIIQEPLVLTEPTRNRLQKKGGKDKT Sbjct: 782 IQKSLAFAYVPVQLSEVGQQVEVELLGKNYPAVIIQEPLVLTEPTRNRLQKKGGKDKT 839 >4P9S-A nrPDB Length = 848 Score = 1597 bits (4136), Expect = 0.0, Method: Compositional matrix adjust. Identities = 766/832 (92%), Positives = 798/832 (95%), Gaps = 2/832 (0%) Query: 32 REGEEKPPLSAETQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWH 91 REG+E PP E WKDRAETVIIGGGCVGVSLAYHLAKAGM+DVVLLEKSELTAGSTWH Sbjct: 8 REGQESPPSPPE--WKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWH 65 Query: 92 AAGLTTYFHPGINLKKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQM 151 AAGLTTYFHPGINLKKIHYDSIKLYE+LEEETGQVVGFHQPGSIRLATTP RVDEFKYQM Sbjct: 66 AAGLTTYFHPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQM 125 Query: 152 TRTGWHATEQYLIEPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGA 211 TRT WHATEQY+IEPEKI E+FPLLNM+K+LAGLYNPGDGHIDPYSLTMALA GARK GA Sbjct: 126 TRTNWHATEQYIIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGA 185 Query: 212 LLKYPAPVTSLKARSDGTWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQ 271 LLKYPAPVTSLK R DGTWDVETPQGS+RANRIVNAAGFWAREVGKMIGL+HPLIPVQHQ Sbjct: 186 LLKYPAPVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQ 245 Query: 272 YVVTSTISEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNGVPP 331 YV+TSTI EVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMK+Q SWV +GVPP Sbjct: 246 YVITSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPP 305 Query: 332 GFGKELFESDLDRIMEHIKAAMEMVPVLKKADIINVVNGPITYSPDILPMVGPHQGVRNY 391 GFGKELFESDLDRI EH++AAMEMVPVLKKADIIN+VNGPITYSPDILPMVGPHQGVRNY Sbjct: 306 GFGKELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNY 365 Query: 392 WVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARESYGF 451 WVAIGFGYGIIHAGGVG YLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARESYGF Sbjct: 366 WVAIGFGYGIIHAGGVGTYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARESYGF 425 Query: 452 NNIVGYPKEERFAGRPTQRVSGLYQRLESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRR 511 NNIVGYPKEERFAGRPTQRVSGLY+ LESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRR Sbjct: 426 NNIVGYPKEERFAGRPTQRVSGLYKILESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRR 485 Query: 512 TNWFEPVGSEYKQVMQRVAVTDLSPFGKFNIKGQDSIRLLDHLFANVIPKVGFTNISHML 571 TNWFEPVGSEYKQVMQRV V DLSPFGKFNIKGQDS +LLDHL ANVIPKVGFTNISHML Sbjct: 486 TNWFEPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPKVGFTNISHML 545 Query: 572 TPKGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEEAVKGGYDVEIKNITDELGVLG 631 TP+GRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEE AV+GGYDVEI+NITDELGVLG Sbjct: 546 TPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLG 605 Query: 632 VAGPQARKVLQKLTSEDLSDDVFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHRREDS 691 VAGP AR+VLQKLTSEDLSDDVFKFLQTKSLK+S+IPVTAIRISYTGELGWELYHRREDS Sbjct: 606 VAGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRREDS 665 Query: 692 VALYDAIMNAGQEEGIDNFGTYAMNALRLEKAFRAWGLEMNCDTNPLEAGLEYFVKLNKP 751 ALY+ IMNAGQEEGIDNFGTYA+NALRLEKAFRAWG EMNCDTNPLEAGL+YF+KLNKP Sbjct: 666 AALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKLNKP 725 Query: 752 ADFIGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESIWYNGKVVGNTTSGSYSYSIQK 811 A+F GKQALKQIKAKGLKRRLVCLTLATD+VDPEGNES+WY GKV+GNTTSGSYSYSIQK Sbjct: 726 ANFTGKQALKQIKAKGLKRRLVCLTLATDNVDPEGNESVWYKGKVIGNTTSGSYSYSIQK 785 Query: 812 SLAFAYVPVQLSEVGQQVEVELLGKNYPAVIIQEPLVLTEPTRNRLQKKGGK 863 SLAFAYVPV+LSEVGQQVEVELLGKNYPA IIQEPLVLTEPTR RLQK G K Sbjct: 786 SLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTEPTRTRLQKDGRK 837 >1PJ5-A nrPDB Length = 830 Score = 352 bits (904), Expect = 3e-97, Method: Compositional matrix adjust. Identities = 243/834 (29%), Positives = 409/834 (49%), Gaps = 42/834 (5%) Query: 53 VIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELT--AGSTWHAAGLTTYFHPGINLKKIHY 110 VIIG G VG +LA L G ++ +L++ L GST HA GL +P + Sbjct: 8 VIIGAGIVGTNLADELVTRGWNNITVLDQGPLNMPGGSTSHAPGLVFQTNPSKTMASFAK 67 Query: 111 DSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLIEPEKIQ 170 +++ L E+ V F+Q G + +ATT R+ + K ++ E L+ P + Q Sbjct: 68 YTVEKLLSLTED--GVSCFNQVGGLEVATTETRLADLKRKLGYAAAWGIEGRLLSPAECQ 125 Query: 171 EMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARSDGTW 230 E++PLL+ +L GL+ P DG L G + VT ++ Sbjct: 126 ELYPLLDGENILGGLHVPSDGLASAARAVQLLIKRTESAGVTYRGSTTVTGIEQSGGRVT 185 Query: 231 DVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYVVTSTISEVKALKRE--- 287 V+T G + A+ +V+ AGFW ++G MIG+ PL+P+ HQYV T+ + + + Sbjct: 186 GVQTADGVIPADIVVSCAGFWGAKIGAMIGMAVPLLPLAHQYVKTTPVPAQQGRNDQPNG 245 Query: 288 --LPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNGVPPGFGKELFESDLDRI 345 LP+LR + Y R+ D G Y + M V + P + S LD Sbjct: 246 ARLPILRHQDQDLYYREHGDRYGIGSY-AHRPMPVDVDTLGAYAPETVSEHHMPSRLDFT 304 Query: 346 MEHI----KAAMEMVPVLKKADIINVVNGPITYSPDILPMVGPHQGVRNYWVAIGFGYGI 401 +E +A +++P L ++I + NG +++PD P++G + + ++VA + Sbjct: 305 LEDFLPAWEATKQLLPALADSEIEDGFNGIFSFTPDGGPLLGESKELDGFYVAEAVW--V 362 Query: 402 IHAGGVGKYLSDWILHGEPPFDLIELDPNRYGK-WTTTQYTEAKARESYGFNNIVGYPKE 460 H+ GV K +++ + G DL E D R+ T +Y +++++ V +P + Sbjct: 363 THSAGVAKAMAELLTTGRSETDLGECDITRFEDVQLTPEYVSETSQQNFVEIYDVLHPLQ 422 Query: 461 ERFAGRPTQRVSGLYQRLESKCSMGFHAG-WEQPHWFYKPGQDTQYRPSFRRTNWFEPV- 518 R + R RVS + R + + AG WE+P+WF + P+ W P Sbjct: 423 PRLSPR-NLRVSPFHARHKELGAFFLEAGGWERPYWFEANAALLKEMPA----EWLPPAR 477 Query: 519 ------------GSEYKQVMQRVAVTDLSPFGKFNIKGQDSIRLLDHLF-ANVIPKVGFT 565 +E + VA+ D++P + + G +++LL L A++ K G Sbjct: 478 DAWSGMFSSPIAAAEAWKTRTAVAMYDMTPLKRLEVSGPGALKLLQELTTADLAKKPGAV 537 Query: 566 NISHMLTPKGRVYAELTVSHQSPGEFLL-ITGSGSELHDLRWIEEEAVKGGYD--VEIKN 622 + +L G V +++TV+ S F L G+ + R + G V++++ Sbjct: 538 TYTLLLDHAGGVRSDITVARLSEDTFQLGANGNIDTAYFERAARHQTQSGSATDWVQVRD 597 Query: 623 ITDELGVLGVAGPQARKVLQKLTSEDLSDDVFKFLQTKSLKVSNIPVTAIRISYTGELGW 682 T +G+ GP AR ++ K++ +D ++D K+ + K++ + IPVTA+R+SY GELGW Sbjct: 598 TTGGTCCIGLWGPLARDLVSKVSDDDFTNDGLKYFRAKNVVIGGIPVTAMRLSYVGELGW 657 Query: 683 ELYHRREDSVALYDAIMNAGQEEGIDNFGTYAMNALRLEKAFRAWGLEMNCDTNPLEAGL 742 ELY ++ L+DA+ AGQ G+ G A ++LRLEK +R+WG +M + +P EAGL Sbjct: 658 ELYTSADNGQRLWDALWQAGQPFGVIAAGRAAFSSLRLEKGYRSWGTDMTTEHDPFEAGL 717 Query: 743 EYFVKLNKPADFIGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESIWYNGKVVGNTTS 802 + VK+ K + FIGK AL+ + RRL CLT+ G E ++Y + VG TS Sbjct: 718 GFAVKMAKES-FIGKGALEGRTEEASARRLRCLTIDDGRSIVLGKEPVFYKEQAVGYVTS 776 Query: 803 GSYSYSIQKSLAFAYVPVQLSEVGQQVEVELLGKNYPAVIIQEPLVLTEPTRNR 856 +Y Y++ K +A++Y+P +S VG V++E G+ A + ++PL + TR R Sbjct: 777 AAYGYTVAKPIAYSYLPGTVS-VGDSVDIEYFGRRITATVTEDPLYDPKMTRLR 829 >1YX2-A nrPDB Length = 365 Score = 165 bits (418), Expect = 6e-41, Method: Compositional matrix adjust. Identities = 100/322 (31%), Positives = 167/322 (51%), Gaps = 9/322 (2%) Query: 515 FEPVGSEYKQVMQRVAVTDLSPFGKFNIKGQDSIRLLDHLFANVIPKV--GFTNISHMLT 572 F + E++ V + D+S G+ + G DS+ L L N + + G + M Sbjct: 33 FSSIKKEHEAVRTAAGLFDVSHMGEVEVSGNDSLSFLQRLMTNDVSALTPGRAQYTAMCY 92 Query: 573 PKGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEEAVKGGYDVEIKNITDELGVLGV 632 P G +L + + +LL+ + + DL W++E A DV+I N +D++ +L V Sbjct: 93 PDGGTVDDLLIYQKGENRYLLVINASNIDKDLAWMKEHAAG---DVQIDNQSDQIALLAV 149 Query: 633 AGPQARKVLQKLTSEDLSD-DVFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHRREDS 691 GP+A +L+ LT D+S F F+ + ++ R YTGE G+E+Y R +D+ Sbjct: 150 QGPKAEAILKNLTDADVSALKPFAFIDEADISGRKALIS--RTGYTGEDGYEIYCRSDDA 207 Query: 692 VALYDAIMNAGQEEGIDNFGTYAMNALRLEKAFRAWGLEMNCDTNPLEAGLEYFVKLNKP 751 + ++ I++AG G+ G A + LR E +G E+ D P+EAG+ + VK K Sbjct: 208 MHIWKKIIDAGDAYGLIPCGLGARDTLRFEANIPLYGQELTRDITPIEAGIGFAVKHKKE 267 Query: 752 ADFIGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESIWYNGKVVGNTTSGSYSYSIQK 811 +DF GK L + K G KR+LV L + + G E ++ NGK VG T+G+ S ++ K Sbjct: 268 SDFFGKSVLSEQKENGAKRKLVGLEMIEKGIPRHGYE-VFQNGKSVGKVTTGTQSPTLGK 326 Query: 812 SLAFAYVPVQLSEVGQQVEVEL 833 ++ A + + SE+G V+VE+ Sbjct: 327 NVGLALIDSETSEIGTVVDVEI 348 >1WOR-A nrPDB Length = 364 Score = 158 bits (400), Expect = 9e-39, Method: Compositional matrix adjust. Identities = 120/386 (31%), Positives = 199/386 (51%), Gaps = 35/386 (9%) Query: 469 QRVSGLYQRLESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFEPVGSEYKQVMQR 528 +R + +E M AGWE P ++ T+ FE E V + Sbjct: 2 KRTPLFEKHVELGAKMVDFAGWEMPLYY---------------TSIFE----EVMAVRKS 42 Query: 529 VAVTDLSPFGKFNIKGQDSIRLLDHLFANVIPKV--GFTNISHMLTPKGRVYAELTVSHQ 586 V + D+S G+F +KG +++ +D L N + G S M G + +L V Sbjct: 43 VGMFDVSHMGEFLVKGPEAVSFIDFLITNDFSSLPDGKAIYSVMCNENGGIIDDLVVYKV 102 Query: 587 SPGEFLLITGSGSELHDLRWIEEEAVKGGYDVEIKNITDELGVLGVAGPQARKVLQKLTS 646 SP E L++ + + D WI+ + +DVE+ NI+D ++ GP+A++ LQ+L Sbjct: 103 SPDEALMVVNAANIEKDFNWIKSHS--KNFDVEVSNISDTTALIAFQGPKAQETLQELV- 159 Query: 647 EDLSDDVFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHRREDSVALYDAIMNAGQEEG 706 ED +++ + KS+ V+ + R YTGE G+EL +++ ++DA+MN ++ Sbjct: 160 EDGLEEIAYYSFRKSI-VAGVETLVSRTGYTGEDGFELMLEAKNAPKVWDALMNLLRKID 218 Query: 707 IDNFGTYAMNALRLEKAFRAWGLEMNCDTNPLEAGLEYFVKLNKPADFIGKQALKQIKAK 766 G A + RLE + +G +M+ +TNP E GL + VKLNK DF+GK+AL + K K Sbjct: 219 GRPAGLGARDVCRLEATYLLYGQDMDENTNPFEVGLSWVVKLNK--DFVGKEALLKAKEK 276 Query: 767 GLKRRLVCLTLATDDVDPEGNESIWYNGKVVGNTTSGSYSYSIQKSLAFAYVPVQLSEVG 826 ++R+LV L L+ + +G E + NG+ VG TSG++S ++ KS+A A V + ++G Sbjct: 277 -VERKLVALELSGKRIARKGYE-VLKNGERVGEITSGNFSPTLGKSIALALVSKSV-KIG 333 Query: 827 QQVEVELLGKNYPAVIIQEPLVLTEP 852 Q LG +P + E LV+ +P Sbjct: 334 DQ-----LGVVFPGGKLVEALVVKKP 354 >1V5V-A nrPDB Length = 401 Score = 123 bits (308), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 96/365 (26%), Positives = 183/365 (50%), Gaps = 38/365 (10%) Query: 514 WFEPVGSEYKQVMQRVAVTDLSPFGKFNIKGQDSIRLLDHLFANVIPKVGFTNISH--ML 571 W+ + E+ V V + D+S G+ +G+D+++ L ++ N I K + ++ +L Sbjct: 32 WYSSIKEEHLAVRNAVGIFDVSHMGEIVFRGKDALKFLQYVTTNDISKPPAISGTYTLVL 91 Query: 572 TPKGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIE------EEAVKGGYDVEIKNITD 625 +G + E V + E+L+I S + W E+ K ++E+K T Sbjct: 92 NERGAIKDETLVFNMGNNEYLMICDSDAFEKLYAWFTYLKRTIEQFTKLDLEIELK--TY 149 Query: 626 ELGVLGVAGPQARKVLQKLTSEDLSDDVFKFLQTKSLKVSNIPVTAIRISYTGELGWELY 685 ++ + V GP+AR + + L D+++ + Q + +++ I + R YTGE G+E+Y Sbjct: 150 DIAMFAVQGPKARDLAKDLFGIDINE--MWWFQARWVELDGIKMLLSRSGYTGENGFEVY 207 Query: 686 -----------HRR---EDSVALYDAIMNAGQEEGIDNFGTYAMNALRLEKAFRAWGLE- 730 +R E ++ +++ I+ G++ GI G A + LRLE + +G E Sbjct: 208 IEDANPYHPDESKRGEPEKALHVWERILEEGKKYGIKPCGLGARDTLRLEAGYTLYGNET 267 Query: 731 -----MNCDTN---PLEAGLEYFVKLNKPADFIGKQALKQIKAKGLKRRLVCLTLATDDV 782 ++ D + PL+A LE+ + +K DFIGK AL + K +G+ R+LV + + Sbjct: 268 KELQLLSTDIDEVTPLQANLEFAIYWDK--DFIGKDALLKQKERGVGRKLVHFKMIDKGI 325 Query: 783 DPEGNESIWYNGKVVGNTTSGSYSYSIQKSLAFAYVPVQLSEVGQQVEVELLGKNYPAVI 842 EG + ++ NG+++G TSG+ S + + A+V + ++ G ++EVE+ G+ AV Sbjct: 326 PREGYK-VYANGEMIGEVTSGTLSPLLNVGIGIAFVKEEYAKPGIEIEVEIRGQRKKAVT 384 Query: 843 IQEPL 847 + P Sbjct: 385 VTPPF 389 >1VRQ-A nrPDB Length = 964 Score = 120 bits (302), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 82/279 (29%), Positives = 138/279 (49%), Gaps = 19/279 (6%) Query: 490 WEQPHWFYKPGQDTQYRPSFRRTNWFEPVGSEYKQVMQRVAVTDLSPFGKFNIKGQDSIR 549 W++P W+Y ++ +R E K V V + D S GK I+G+D+ Sbjct: 595 WKRP-WYYPQDGESMDEAVYR----------ECKAVRDSVGMLDASTLGKIEIRGKDAAE 643 Query: 550 LLDHLFAN--VIPKVGFTNISHMLTPKGRVYAELTVSHQSPGEFLLITGSGSELHDLRWI 607 L+ ++ N KVG M G ++ + + FL+ T +G L W+ Sbjct: 644 FLNRMYTNGYTKLKVGMGRYGVMCKADGMIFDDGVTLRLAEDRFLMHTTTGGAADVLDWL 703 Query: 608 EE--EAVKGGYDVEIKNITDELGVLGVAGPQARKVLQKLTSE-DLSDDVFKFLQTKSLKV 664 EE + DV ++T++L + V GP++R V+ KL S D+S+D FKF+ + + + Sbjct: 704 EEWLQTEWPELDVTCTSVTEQLATVAVVGPRSRDVIAKLASSLDVSNDAFKFMAFQDVTL 763 Query: 665 -SNIPVTAIRISYTGELGWELYHRREDSVALYDAIMNAGQEEGIDNFGTYAMNALRLEKA 723 S I RIS++GEL +E+ + +++ + AGQE I +GT M+ LR EK Sbjct: 764 DSGIEARISRISFSGELAFEIAIPAWHGLQVWEDVYAAGQEFNITPYGTETMHVLRAEKG 823 Query: 724 FRAWGLEMNCDTNPLEAGLEYFVKLNKPADFIGKQALKQ 762 F G + + P +AG+E+ V +K DF+GK++ + Sbjct: 824 FIIVGQDTDGTVTPQDAGMEWVV--SKLKDFVGKRSFSR 860 >2GAG-A nrPDB Length = 965 Score = 118 bits (295), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 85/293 (29%), Positives = 146/293 (49%), Gaps = 20/293 (6%) Query: 490 WEQPHWFYKPGQDTQYRPSFRRTNWFEPVGSEYKQVMQRVAVTDLSPFGKFNIKGQDSIR 549 W++P W+Y +T + +R E K V V + D + GK I+G+D+ Sbjct: 596 WKRP-WYYPQAGETMDQAVYR----------ESKAVRDSVGMLDATTLGKIEIRGKDAAE 644 Query: 550 LLDHLFAN--VIPKVGFTNISHMLTPKGRVYAELTVSHQSPGEFLLITGSGSELHDLRWI 607 L+ ++ N KVG M G ++ + + FLL T +G L W+ Sbjct: 645 FLNRIYTNGYTKLKVGMGRYGVMCKADGMIFDDGVTLRLAEDRFLLHTTTGGAADVLDWL 704 Query: 608 EE--EAVKGGYDVEIKNITDELGVLGVAGPQARKVLQKLTSE-DLSDDVFKFLQTKSLKV 664 EE + DV ++T++L + V GP++R V+ KL S D+S++ FKF+ K + + Sbjct: 705 EEWLQTEWPDLDVTCTSVTEQLATVAVVGPRSRDVIAKLASTVDVSNEGFKFMAFKDVVL 764 Query: 665 -SNIPVTAIRISYTGELGWELYHRREDSVALYDAIMNAGQEEGIDNFGTYAMNALRLEKA 723 S I RIS++GEL +E+ + +++ + AG+E I +GT M+ LR EK Sbjct: 765 DSGIEARISRISFSGELAFEIAVPAWHGLRVWEDVYAAGEEFNITPYGTETMHVLRAEKG 824 Query: 724 FRAWGLEMNCDTNPLEAGLEYFVKLNKPADFIGKQALKQI-KAKGLKRRLVCL 775 F G + + P +AG+E+ V +K DFIG ++ + A+ +++LV + Sbjct: 825 FIIVGQDTDGTVTPQDAGMEWVV--SKLKDFIGNRSYSRADNAREDRKQLVSV 875 >1WSR-A nrPDB Length = 375 Score = 95.1 bits (235), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 100/376 (26%), Positives = 167/376 (44%), Gaps = 44/376 (11%) Query: 488 AGWEQPHWFYKPGQDTQYRPSFRRTNWFEPVGSEYKQVMQRVAVTDLSPFGKFNIKGQDS 547 AGW P QYR S ++ Q ++ D+S + I G D Sbjct: 25 AGWSLP---------VQYRDSHTDSHL---------HTRQHCSLFDVSHMLQTKILGSDR 66 Query: 548 IRLLDHL----FANVIPKVGFTNISHMLTPKGRVYAELTVSHQSPGEFLLITGSGSELHD 603 ++L++ L A + P G +S G + +L V++ S G +++ +G D Sbjct: 67 VKLMESLVVGDIAELRPNQG--TLSLFTNEAGGILDDLIVTNTSEGHLYVVSNAGCWEKD 124 Query: 604 LRWIEE---EAVKGGYDVEIKNITDELGVLGVAGPQARKVLQKLTSEDLSDDVFKFLQTK 660 L +++ E G DV ++ + + L L + GP A +VLQ ++DL F+ + Sbjct: 125 LALMQDKVRELQNQGRDVGLEVLDNAL--LALQGPTAAQVLQAGVADDLRK--LPFMTSA 180 Query: 661 SLKVSNIP-VTAIRISYTGELGWELYHRREDSVALYDAIMNAGQEEGIDNFGTYAMNALR 719 ++V + R YTGE G E+ +V L AI+ + + G A ++LR Sbjct: 181 VMEVFGVSGCRVTRCGYTGEDGVEISVPVAGAVHLATAILKNPE---VKLAGLAARDSLR 237 Query: 720 LEKAFRAWGLEMNCDTNPLEAGLEYFVKLNKPA--DFIGKQAL-KQIKAKGLKRR--LVC 774 LE +G +++ T P+E L + + + A DF G + + Q+K + +RR L+C Sbjct: 238 LEAGLCLYGNDIDEHTTPVEGSLSWTLGKRRRAAMDFPGAKVIVPQLKGRVQRRRVGLMC 297 Query: 775 LTLATDDVDPEGNESIWYNGKVVGNTTSGSYSYSIQKSLAFAYVPVQLSEVGQQVEVELL 834 P N G +G TSG S S++K++A YVP + S G + VE+ Sbjct: 298 EGAPMRAHSPILN----MEGTKIGTVTSGCPSPSLKKNVAMGYVPCEYSRPGTMLLVEVR 353 Query: 835 GKNYPAVIIQEPLVLT 850 K AV+ + P V T Sbjct: 354 RKQQMAVVSKMPFVPT 369 >3A8J-A nrPDB Length = 364 Score = 90.5 bits (223), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 94/360 (26%), Positives = 160/360 (44%), Gaps = 51/360 (14%) Query: 514 WFEPV--GS---EYKQVMQRVAVTDLSPFGKFNIKGQDSIRLLDHLFANVIPKV---GFT 565 W P+ GS E+ V + D+S +++G + L +L AN + K+ G Sbjct: 24 WMMPLHYGSQIDEHHAVRTDAGMFDVSHMTIVDLRGSRTREFLRYLLANDVAKLTKSGKA 83 Query: 566 NISHMLTPKGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEEAVKGGYDVEIKNITD 625 S ML G V +L V + + F L+ S + DL WI + A G ++ ++ D Sbjct: 84 LYSGMLNASGGVIDDLIVYYFTEDFFRLVVNSATREKDLSWITQHAEPFGIEITVR---D 140 Query: 626 ELGVLGVAGPQARKVLQKLTSEDLSDDV-----FKFLQTKSLKVSNIPVTAIRISYTGEL 680 +L ++ V GP A+ L ++ V F +Q L ++ YTGE Sbjct: 141 DLSMIAVQGPNAQAKAATLFNDAQRQAVEGMKPFFGVQAGDLFIATT-------GYTGEA 193 Query: 681 GWELYHRREDSVALYDAIMNAGQEEGIDNFGTYAMNALRLEKAFRAWGLEMNCDTNPLEA 740 G+E+ E + + A++ E G+ G A + LRLE +G EM+ +PL A Sbjct: 194 GYEIALPNEKAADFWRALV----EAGVKPCGLGARDTLRLEAGMNLYGQEMDETISPLAA 249 Query: 741 GLEYFVKLNKPA--DFIGKQALKQIKAKGLKRRLVCLTLATDDV----------DPEGNE 788 + + + +PA DFIG++AL+ + G + +LV L + V D +GN+ Sbjct: 250 NMGWTIAW-EPADRDFIGREALEVQREHGTE-KLVGLVMTEKGVLRNELPVRFTDAQGNQ 307 Query: 789 SIWYNGKVVGNTTSGSYSYSIQKSLAFAYVPVQLSEVGQQVEVELLGKNYPAVIIQEPLV 848 G TSG++S ++ S+A A VP +G+ V++ + P + + V Sbjct: 308 H-------EGIITSGTFSPTLGYSIALARVP---EGIGETAIVQIRNREMPVKVTKPVFV 357 >3GIR-A nrPDB Length = 393 Score = 80.9 bits (198), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 86/338 (25%), Positives = 144/338 (42%), Gaps = 19/338 (5%) Query: 517 PVG--SEYKQVMQRVAVTDLSPFGKFNIKGQDSIRLLDHLFA--NVIPKVGFTNISHMLT 572 P+G E+ + D+S ++G ++ L + + K+G + S++L Sbjct: 62 PLGVLKEHLHTRAHAGLFDISHMKLIAVEGPKAVEFLSYALPVDAALLKIGQSRYSYLLN 121 Query: 573 PKGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEEAVKGGYDVEIKNITDELGVLGV 632 + + +L ++ + F+L+ +G+ D +E+ A + E + I E +L + Sbjct: 122 ERAGILDDLILTRLAECRFMLVANAGNAQADFAELEKRA----FGFECQVIALERVLLAL 177 Query: 633 AGPQARKVLQKLTSEDLSDDVFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHRREDSV 692 GPQA VL L + F+Q + + +T R YTGE G+E+ + Sbjct: 178 QGPQAAAVL---ADAGLPGNELLFMQGFEPQ-QDWFIT--RSGYTGEDGFEIALPIGCAR 231 Query: 693 ALYDAIMNAGQEEGIDNFGTYAMNALRLEKAFRAWGLEMNCDTNPLEAGLEYFVKLN--K 750 AL + ++ + E + G A ++LRLE G ++ DT P++A L + V N + Sbjct: 232 ALAEKLLGDSRVEWV---GLAARDSLRLEAGLCLHGNDITPDTTPIDAALTWAVPKNVRE 288 Query: 751 PADFIGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESIWYNGKVVGNTTSGSYSYSIQ 810 A F G +A + KG R V L T G G +G TSG + S Sbjct: 289 KAQFYGAKAFLESLQKGPSRCRVGLKPQTRQPIRAGAVLFDNEGNRIGVVTSGGFGPSFD 348 Query: 811 KSLAFAYVPVQLSEVGQQVEVELLGKNYPAVIIQEPLV 848 +A YVPV G +V EL GK + P V Sbjct: 349 GPVAMGYVPVAWKVEGTEVFTELRGKKIALSVHSLPFV 386 >2GAG-B nrPDB Length = 405 Score = 78.2 bits (191), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 92/397 (23%), Positives = 169/397 (42%), Gaps = 34/397 (8%) Query: 40 LSAETQWKDRAETVIIGGGCVGVSLAYHLAKA-GMKDVVLLEKSELTAGSTWHAAGLTTY 98 L A + K + +I+GGG G++ AY LAK G+ +V +LEK L G+ + Sbjct: 12 LWANPEPKKSYDAIIVGGGGHGLATAYFLAKNHGITNVAVLEKGWLAGGNMARNTTIIRS 71 Query: 99 FHPGINLKKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHA 158 + I+ S+KL+E+L E+ F Q G + LA T V E ++ + Sbjct: 72 NYLWDESAGIYEKSLKLWEQLPEDLEYDFLFSQRGVLNLAHTLGDVRESVRRVEANKLNG 131 Query: 159 TEQYLIEPEKIQEMFPLLNMNK-----VLAGLYNPGDGHIDPYSLTMALAAGARKCGALL 213 + ++P +++E P++N + V+ + P G + A A A + G + Sbjct: 132 VDAEWLDPSQVKEACPIINTSDDIRYPVMGATWQPRAGIAKHDHVAWAFARKANEMGVDI 191 Query: 214 KYPAPVTSLKARSDGTWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYV 273 VT + V+T +G++ A ++ A + + +M G E +P+Q + Sbjct: 192 IQNCEVTGFIKDGEKVTGVKTTRGTIHAGKVALAGAGHSSVLAEMAGFE---LPIQ-SHP 247 Query: 274 VTSTISEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNGVPPGF 333 + + +SE+ V+ + Y + + L+ G DS+ G+ Sbjct: 248 LQALVSELFEPVHPTVVMSNHIHVYVSQAHKGELVMG--------AGIDSY------NGY 293 Query: 334 GKELFESDLDRIMEHIKAAMEMVPVLKKADIINVVNGPITYSPDILPMVGPHQGVRNYWV 393 G+ I E + AA+E+ P+ +A ++ G + + D P++ ++N +V Sbjct: 294 GQ---RGAFHVIQEQMAAAVELFPIFARAHVLRTWGGIVDTTMDASPIISK-TPIQNLYV 349 Query: 394 AIGFGYGIIHAG-GVGKYLSDWILHGEP-----PFDL 424 G+G G G G L+ I + EP PF L Sbjct: 350 NCGWGTGGFKGTPGAGFTLAHTIANDEPHELNKPFSL 386 >3TFJ-A nrPDB Length = 369 Score = 71.6 bits (174), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 71/345 (20%), Positives = 153/345 (44%), Gaps = 27/345 (7%) Query: 515 FEPVGSEYKQVMQRVAVTDLSPFGKFNIKGQDSIRLLDHLFANVIPK--VGFTNISHMLT 572 F + YK + + V + D++ + I G+DS L+ + + K +G ++ Sbjct: 41 FGSIEDSYKHLKEHVQIWDVAAERQVEISGKDSAELVQLMTCRDLSKSKIGRCYYCPIID 100 Query: 573 PKGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEEAVKGGYDVEIKNITDELGVLGV 632 G + + V ++ + + + + G+ ++K + + ++ + Sbjct: 101 ENGNLVNDPVVLKLDENKWWISIADSDVIFFAK-----GLASGHKFDVKIVEPVVDIMAI 155 Query: 633 AGPQARKVLQKLTSEDLSD------DVFKFLQTKSLKVSNIPVTAIRISYTGELGWELY- 685 GP++ +++K+ + +++ D F F TK L R ++ + G+E+Y Sbjct: 156 QGPKSFALMEKVFGKKITELKFFGFDYFDFEGTKHL--------IARSGWSKQGGYEVYV 207 Query: 686 HRREDSVALYDAIMNAGQEEGIDNFGTYAMNAL-RLEKAFRAWGLEMNCDTNPLEAGLEY 744 + LYD + G+E N G N + R+E A ++G + + + NP E G + Sbjct: 208 ENTQSGQKLYDHLFEVGKEF---NVGPGCPNLIERIESALLSYGNDFDNNDNPFECGFDQ 264 Query: 745 FVKLNKPADFIGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESIW-YNGKVVGNTTSG 803 +V L+ +F+GK+ LK+IK KG +++L + + ++ G+++I+ N V+G S Sbjct: 265 YVSLDSDINFLGKEKLKEIKLKGPQKKLRGVKIDIKEISLTGSKNIYDENNNVIGELRSA 324 Query: 804 SYSYSIQKSLAFAYVPVQLSEVGQQVEVELLGKNYPAVIIQEPLV 848 YS QK + A + E Q ++++ + P + Sbjct: 325 CYSPHFQKVIGIAMIKKSHWEASQGFKIQINDNTINGNVCDLPFI 369 >4YSH-A nrPDB Length = 376 Score = 69.7 bits (169), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 87/325 (26%), Positives = 145/325 (44%), Gaps = 38/325 (11%) Query: 115 LYEKLEEETGQVVGFHQPGSIRLATTPVRVDE-FKYQMTRTGWHATEQYLIEPEKIQEMF 173 L E+L E TG +G + G I+LATT D+ +++ G Q+L + E + EM Sbjct: 76 LAEELRERTGIDIGLVEKGLIKLATTEEEADDLYRHYTFWRGIGEPVQWLTKGEAL-EME 134 Query: 174 PLLNMNKVLAG-LYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARSDGTWDV 232 P + + LAG +Y PGDG + L ALA A GA L V +++ S G + Sbjct: 135 P--RLAEALAGAMYIPGDGQVSAPDLAAALAYAAASAGACLYEYTEVFDIRSDSSGHV-L 191 Query: 233 ETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYVVTSTISEVKALKRELPVLR 292 +T G+ A +V A+G WA +G +GL + PV+ + V+ ++ +P+L+ Sbjct: 192 DTTGGTFAAEAVVIASGAWAARLGARVGLSLSVYPVKGECVM---------VRAPVPLLQ 242 Query: 293 DL----EGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNGVPPGFGKELFESDLDRIMEH 348 G Y + + + LL G P F + + +M Sbjct: 243 TTVFAKNGCYIVPKSGNRLLIG---------------ATSTPGTFDRRVSAGG---VMNL 284 Query: 349 IKAAMEMVPVLKKADIINVVNGPITYSPDILPMVGPHQGVRNYWVAIG-FGYGIIHAGGV 407 + A +VP +++A+ + +G + D LP +G H R +VA G + GI+ + Sbjct: 285 LHRAAHLVPDIEQAEWVASWSGIRPQTEDGLPYLGEHPERRGLFVAAGHYRNGILLSPLT 344 Query: 408 GKYLSDWILHGEPPFDLIELDPNRY 432 G ++D + E FDL R+ Sbjct: 345 GLLVADLVERKETAFDLAPFSLTRH 369 >1NG3-A nrPDB Length = 390 Score = 63.5 bits (153), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 86/367 (23%), Positives = 150/367 (40%), Gaps = 50/367 (13%) Query: 66 YHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYD----SIKLYEKLEE 121 Y+LAK K+ L E + +T AAG+ H + +D S +LY+ L E Sbjct: 42 YYLAKEN-KNTALFESGTMGGRTTSAAAGMLGA-HAECEERDAFFDFAMHSQRLYKGLGE 99 Query: 122 ETGQVVGF----HQPGSIRLATTPVRVDEFKY--QMTRTGWHATEQYL-IEPEKIQEMFP 174 E + G H G +LA + V + + + W++ E+ L EP ++F Sbjct: 100 ELYALSGVDIRQHNGGMFKLAFSEEDVLQLRQMDDLDSVSWYSKEEVLEKEPYASGDIF- 158 Query: 175 LLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARSDGTWDVET 234 + D H++PY + A A+ GA + PV ++ + + ++T Sbjct: 159 --------GASFIQDDVHVEPYFVCKAYVKAAKMLGAEIFEHTPVLHVERDGEALF-IKT 209 Query: 235 PQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYVVTSTISEVKALKRELPVLRDL 294 P G + AN +V A+G W+ K +GL + +PV+ + + ++P+ + L Sbjct: 210 PSGDVWANHVVVASGVWSGMFFKQLGLNNAFLPVKGEC--------LSVWNDDIPLTKTL 261 Query: 295 EGSY-YLRQERDGLLFGPYESQEKMKVQDSWVTNGVPPGFGKELFESDLDRIMEHIKAAM 353 + Y+ + G L V + PG E DL + +K A Sbjct: 262 YHDHCYIVPRKSGRLV---------------VGATMKPGDWSE--TPDLGGLESVMKKAK 304 Query: 354 EMVPVLKKADIINVVNGPITYSPDILPMVGPH-QGVRNYWVAIGFGYGIIHAGGVGKYLS 412 M+P ++ + G + D P +G H + R + A F GI+ A G +S Sbjct: 305 TMLPPIQNMKVDRFWAGLRPGTKDGKPYIGRHPEDSRILFAAGHFRNGILLAPATGALIS 364 Query: 413 DWILHGE 419 D I++ E Sbjct: 365 DLIMNKE 371 >3SM8-A nrPDB Length = 381 Score = 59.7 bits (143), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 64/284 (22%), Positives = 114/284 (40%), Gaps = 27/284 (9%) Query: 50 AETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIH 109 A+ ++IG G G S Y L+ G + VVL +++ ST +A T + ++ + Sbjct: 10 ADYLVIGAGIAGASTGYWLSAHG-RVVVLEREAQPGYHSTGRSAAHYTVAYGTPQVRALT 68 Query: 110 YDSIKLYEK----------LEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHAT 159 S ++ L VV F +E + Q Sbjct: 69 AASRAFFDNPPAGFCEHPLLSPRPEMVVDFSD-----------DPEELRRQYESGKALVP 117 Query: 160 EQYLIEPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPV 219 + L++ E+ + P+L +KV Y+P ID +L G R+ + Sbjct: 118 QMRLLDAEQACSIVPVLRRDKVFGATYDPTGADIDTDALHQGYLRGIRRNQGQVLCNHEA 177 Query: 220 TSLKARSDGTWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEH-PLIPVQHQYVVTSTI 278 ++ R DG W+V GS RA +VNAAG W + + G+ L P + + + Sbjct: 178 LEIR-RVDGAWEVRCDAGSYRAAVLVNAAGAWCDAIAGLAGVRPLGLQPKRRSAFIFAPP 236 Query: 279 SEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQD 322 + + P+L L+ S+YL+ + G+L G + + ++ D Sbjct: 237 PGIDC--HDWPMLVSLDESFYLKPDA-GMLLGSPANADPVEAHD 277 >3AD9-B nrPDB Length = 404 Score = 58.9 bits (141), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 87/382 (22%), Positives = 159/382 (41%), Gaps = 48/382 (12%) Query: 62 VSLAYHLAK-AGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYEKLE 120 ++ AY+LAK G+ +V +LEK L G+ A TT I + +S +YEK Sbjct: 33 LATAYYLAKNHGITNVAVLEKGWLAGGNM---ARNTTI----IRSNYLWDESAGIYEKSL 85 Query: 121 EETGQVVG-------FHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLIEPEKIQEMF 173 + ++ F Q G + LA T V E ++ ++ + + PE+++E+ Sbjct: 86 KLWEELPEELEYDFLFSQRGVLNLAHTLGDVRESIRRVEANKFNGVDAEWLTPEQVKEVC 145 Query: 174 PLLNMNK-----VLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARSDG 228 P++N V+ Y P G + A A A + G + VT + Sbjct: 146 PIINTGDNIRYPVMGATYQPRAGIAKHDHVAWAFARKANEMGVDIIQNCEVTGFLKDGEK 205 Query: 229 TWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYVVTSTISEVKALKREL 288 V+T +G++ A ++ A + + ++ G E +P+Q + + + +SE+ Sbjct: 206 VTGVKTTRGTILAGKVALAGAGHSSVLAELAGFE---LPIQ-SHPLQALVSELFEPVHPT 261 Query: 289 PVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNGVPPGFGKELFESDLDRIMEH 348 V+ + Y + + L+ G DS+ G+G+ I E Sbjct: 262 VVMSNHIHVYVSQAHKGELVMG--------AGIDSY------NGYGQ---RGAFHVIEEQ 304 Query: 349 IKAAMEMVPVLKKADIINVVNGPITYSPDILPMVGPHQGVRNYWVAIGFGYGIIHAG-GV 407 + AA+E+ P+ +A ++ G + + D P++ ++N +V G+G G G Sbjct: 305 MAAAVELFPIFARAHVLRTWGGIVDTTMDASPIISK-TPIQNLYVNCGWGTGGFKGTPGA 363 Query: 408 GKYLSDWILHGEP-----PFDL 424 G L+ I H EP PF L Sbjct: 364 GYTLAHTIAHDEPHKLNAPFAL 385 >1ZOV-A nrPDB Length = 386 Score = 44.7 bits (104), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 52/228 (22%), Positives = 102/228 (44%), Gaps = 23/228 (10%) Query: 51 ETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSE--LTAGSTW-------HAAGLTTYFHP 101 + +++G G +G++ Y+LAK G+K +L++ + T GS HA G + P Sbjct: 5 DVIVVGAGSMGMAAGYYLAKQGVK-TLLVDSFDPPHTNGSHHGDTRIIRHAYGEGREYVP 63 Query: 102 -GINLKKIHYDSIK-LYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHAT 159 + +++ Y+ K + K+ +TG +V + GS ++ T M H+ Sbjct: 64 FALRAQELWYELEKETHHKIFTQTGVLVYGPKGGSAFVSET----------MEAANIHSL 113 Query: 160 EQYLIEPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPV 219 E L E +++ + + + + ++ P G + + A A GA + PV Sbjct: 114 EHELFEGKQLTDRWAGVEVPDNYEAIFEPNSGVLFSENCIQAYRELAEAHGATVLTYTPV 173 Query: 220 TSLKARSDGTWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIP 267 + D ++T +GS AN++V + G W ++ + +E PL P Sbjct: 174 EDFEVTED-LVTIKTAKGSYTANKLVVSMGAWNSKLLSKLDVEIPLQP 220 >3BHF-A nrPDB Length = 390 Score = 42.0 bits (97), Expect = 0.001, Method: Compositional matrix adjust. Identities = 81/393 (20%), Positives = 163/393 (41%), Gaps = 32/393 (8%) Query: 51 ETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHP---GINLKK 107 + +++G G +G++ Y LAK G+K +L++ + + H H G Sbjct: 6 DVIVVGAGSMGMAAGYQLAKQGVK-TLLVDAFDPPHTNGSHHGDTKIIRHAYGEGREYVP 64 Query: 108 IHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQ-MTRTGWHATEQYLIEP 166 + S +L+ +LE+ET + F + G + P F + M H+ L+E Sbjct: 65 LALRSQELWYELEKETHHKI-FTKTGVLVFG--PKGESAFVAETMEAAKEHSLTVDLLEG 121 Query: 167 EKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARS 226 ++I + +P + + + ++ P G + + A A GA + V Sbjct: 122 DEINKRWPGITVPENYNAIFEPNSGVLFSENCIRAYRELAEARGAKVLTHTRVEDFDISP 181 Query: 227 DGTWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYVVTSTISEVKALKR 286 D + +ET GS A++++ + G W ++ + L+ PL P ++ VV S+ Sbjct: 182 D-SVKIETANGSYTADKLIVSMGAWNSKLLSKLNLDIPLQP--YRQVVGFFESD------ 232 Query: 287 ELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNGVPPGFGKELFESDLDRIM 346 E D++ ++ + +G+ +G + S ++ + T FG+++ ++R Sbjct: 233 ESKYSNDIDFPGFMVEVPNGIYYG-FPSFGGCGLKLGYHT------FGQKIDPDTINREF 285 Query: 347 -------EHIKAAMEMVPVLKKADIINVVNGPITYSPDILPMVGPHQGVRNYWVAIGF-G 398 +++A +E ++ T + D ++ H N +A GF G Sbjct: 286 GVYPEDESNLRAFLEEYMPGANGELKRGAVCMYTKTLDEHFIIDLHPEHSNVVIAAGFSG 345 Query: 399 YGIIHAGGVGKYLSDWILHGEPPFDLIELDPNR 431 +G + GVG+ LS L G+ D+ NR Sbjct: 346 HGFKFSSGVGEVLSQLALTGKTEHDISIFSINR 378 >2UZZ-A nrPDB Length = 372 Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust. Identities = 85/408 (20%), Positives = 148/408 (36%), Gaps = 62/408 (15%) Query: 49 RAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTA-------GSTW---HAAGLTTY 98 + + +IIG G VG + Y+ +AG+ VL+ + + G T HA G Sbjct: 2 KYDLIIIGSGSVGAAAGYYATRAGLN--VLMTDAHMPPHQHGSHHGDTRLIRHAYGEGEK 59 Query: 99 FHPGINLKKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHA 158 + P + ++ L+++L F + G I L H+ Sbjct: 60 YVPLVLRAQM------LWDELSRHNEDDPIFVRSGVINLGPA-------DSTFLANVAHS 106 Query: 159 TEQYLIEPEK-----IQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALL 213 EQ+ + EK I +P + + GL+ G + A++ G Sbjct: 107 AEQWQLNVEKLDAQGIMARWPEIRVPDNYIGLFETDSGFLRSELAIKTWIQLAKEAGCAQ 166 Query: 214 KYPAPVTSLKARSDGTWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYV 273 + PVT+++ DG +ET G +A + + AG W +++ E P+ PV+ + Sbjct: 167 LFNCPVTAIRHDDDGV-TIETADGEYQAKKAIVCAGTWVKDLLP----ELPVQPVRKVFA 221 Query: 274 ------VTSTISEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTN 327 S ++ A ELP + + Y E D L G + + + D V Sbjct: 222 WYQADGRYSVKNKFPAFTGELP---NGDQYYGFPAENDALKIGKHNGGQVIHSADERVPF 278 Query: 328 GVPPGFGKELFESDLDRIMEHIKAAMEMVPVLKKADIINVVNGPITY--SPDILPMVGPH 385 G E F L ++ I + TY SPD ++ Sbjct: 279 AEVVSDGSEAFPF-LRNVLPGIGCCL--------------YGAACTYDNSPDEDFIIDTL 323 Query: 386 QGVRNYWVAIGF-GYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRY 432 G N + G G+G A +G+ +D+ + FDL +R+ Sbjct: 324 PGHDNTLLITGLSGHGFKFASVLGEIAADFAQDKKSDFDLTPFRLSRF 371 >2GAH-C nrPDB Length = 210 Score = 39.7 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 31/101 (30%), Positives = 44/101 (43%), Gaps = 7/101 (6%) Query: 587 SPGEFLLITGSGSELHDLRWIEEEAVKGGYDVEIKNITDELGVLGVAGPQARKVLQKLTS 646 +P EFL + +EL + A G ++ +++ VL + GP A VL+K Sbjct: 85 APDEFLATSAENTELGGVL----SAALGDAPGQVVDLSANRSVLELTGPDAPLVLRKSCP 140 Query: 647 EDLSDDVFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHR 687 DL F Q V+NIPV R TGE W + R Sbjct: 141 ADLHPRAFAVNQAIVTSVANIPVLLWR---TGEQAWRIMPR 178 >1KNR-A nrPDB Length = 540 Score = 34.7 bits (78), Expect = 0.17, Method: Compositional matrix adjust. Identities = 19/45 (42%), Positives = 27/45 (60%), Gaps = 2/45 (4%) Query: 50 AETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAG 94 + +IIG G G+SLA LA V++L K +T GST++A G Sbjct: 9 CDVLIIGSGAAGLSLALRLAD--QHQVIVLSKGPVTEGSTFYAQG 51 >4IV9-A nrPDB Length = 557 Score = 34.7 bits (78), Expect = 0.18, Method: Compositional matrix adjust. Identities = 16/40 (40%), Positives = 21/40 (52%) Query: 51 ETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTW 90 I+G G G+ A L +AG+KDVVL E + G W Sbjct: 40 RVAIVGAGISGLVAATELLRAGVKDVVLYESRDRIGGRVW 79 >3BIQ-A nrPDB Length = 467 Score = 34.3 bits (77), Expect = 0.26, Method: Compositional matrix adjust. Identities = 42/143 (29%), Positives = 70/143 (48%), Gaps = 21/143 (14%) Query: 318 MKVQDSWVTNGVPPGFG-KELFESDLDRIMEHI-KAAMEMVPVLKKADIINVVNGPITYS 375 + +Q VTN + PG KE++ES ++E+I K E+VP K +I +++ S Sbjct: 323 LTLQKEIVTNILKPGRTPKEVYES----VIEYIEKTKPELVPNFTK-NIGSLIGLEFRDS 377 Query: 376 PDILPMVGPHQGV-RNYWVAIGFGYGIIH----AGGVGKYLSDWILHGEPPFDLIELDPN 430 IL + ++ + R I FG+ + A L+D + + P D E +P Sbjct: 378 NFILNVKNDYRKIQRGDCFNISFGFNNLKDSQSANNYALQLADTV---QIPLD--ETEPP 432 Query: 431 RYGKWTTTQYTEAKARESYGFNN 453 R+ T YT+AK++ S+ FNN Sbjct: 433 RF----LTNYTKAKSQISFYFNN 451 >4C5O-A nrPDB Length = 357 Score = 33.9 bits (76), Expect = 0.30, Method: Compositional matrix adjust. Identities = 17/46 (36%), Positives = 26/46 (56%), Gaps = 2/46 (4%) Query: 48 DRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAA 93 D + V+IGGG G+S Y L ++G+ V+L +E + G W A Sbjct: 2 DSVDVVVIGGGQSGLSAGYFLRRSGLSYVIL--DAEASPGGAWQHA 45 >5KXJ-A nrPDB Length = 557 Score = 33.5 bits (75), Expect = 0.37, Method: Compositional matrix adjust. Identities = 18/45 (40%), Positives = 28/45 (62%), Gaps = 2/45 (4%) Query: 50 AETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAG 94 + +IIG G G+SLA LA+ V++L K ++ GST++A G Sbjct: 9 CDVLIIGSGAAGLSLALRLAEK--HKVIVLSKGPVSEGSTFYAQG 51 >1VRQ-C nrPDB Length = 206 Score = 33.5 bits (75), Expect = 0.40, Method: Composition-based stats. Identities = 29/100 (29%), Positives = 42/100 (42%), Gaps = 7/100 (7%) Query: 588 PGEFLLITGSGSELHDLRWIEEEAVKGGYDVEIKNITDELGVLGVAGPQARKVLQKLTSE 647 P EFLL L D + G ++ +++ VL + GP A VL+K Sbjct: 84 PDEFLLAAEENPALLDTL----QGALGQEPGQVLDLSANRSVLQLEGPAAALVLRKSCPA 139 Query: 648 DLSDDVFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHR 687 DL F + + ++NIPV R TGE W + R Sbjct: 140 DLHPREFGVNRAITTSLANIPVLLWR---TGEQSWRILPR 176 >3S2F-A nrPDB Length = 340 Score = 33.1 bits (74), Expect = 0.58, Method: Compositional matrix adjust. Identities = 18/54 (33%), Positives = 30/54 (55%), Gaps = 1/54 (1%) Query: 550 LLDHLFANVIP-KVGFTNISHMLTPKGRVYAELTVSHQSPGEFLLITGSGSELH 602 + D + ++P KVGF I+ +L VY L V+ PG++++I+G G H Sbjct: 127 VADPNYVGLLPDKVGFVEIAPILCAGVTVYKGLKVTDTRPGQWVVISGIGGLGH 180 >6QZO-A nrPDB Length = 383 Score = 32.7 bits (73), Expect = 0.68, Method: Compositional matrix adjust. Identities = 16/37 (43%), Positives = 21/37 (56%), Gaps = 1/37 (2%) Query: 393 VAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIELDP 429 V +GFG G++ A G+ W LH PPF + LDP Sbjct: 101 VTVGFGPGLLTAAGLRHRAPAW-LHPLPPFGIDRLDP 136 >3L1R-A nrPDB Length = 478 Score = 32.7 bits (73), Expect = 0.70, Method: Compositional matrix adjust. Identities = 12/36 (33%), Positives = 24/36 (66%) Query: 52 TVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAG 87 +++G G G+S A L++AG+ D+++LE ++ G Sbjct: 7 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGG 42 >5MOG-A nrPDB Length = 497 Score = 32.7 bits (73), Expect = 0.73, Method: Compositional matrix adjust. Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 10/67 (14%) Query: 51 ETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGST---------WHAAGLTTYFHP 101 + VI G G G+S A +LA AG K +LLE ++ G W+ GL +F Sbjct: 19 QVVIAGAGLAGLSTAKYLADAGHKP-ILLEARDVLGGKIAAWKDEDGDWYETGLHIFFGA 77 Query: 102 GINLKKI 108 N++ + Sbjct: 78 YPNIQNL 84 >2JB2-A nrPDB Length = 489 Score = 32.3 bits (72), Expect = 0.81, Method: Compositional matrix adjust. Identities = 18/42 (42%), Positives = 23/42 (54%), Gaps = 1/42 (2%) Query: 53 VIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAG 94 V++GGG G+ A+ L KAG K V +LE G W A G Sbjct: 15 VVLGGGPAGLCSAFELQKAGYK-VTVLEARTRPGGRVWTARG 55 >3KVE-A nrPDB Length = 486 Score = 32.3 bits (72), Expect = 1.0, Method: Compositional matrix adjust. Identities = 18/35 (51%), Positives = 22/35 (62%), Gaps = 1/35 (2%) Query: 53 VIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAG 87 V++G G G+S AY LA AG K V +LE SE G Sbjct: 37 VVVGAGMSGLSAAYVLAGAGHK-VTVLEASERAGG 70 >5V0C-Z nrPDB Length = 358 Score = 32.0 bits (71), Expect = 1.1, Method: Compositional matrix adjust. Identities = 26/97 (26%), Positives = 47/97 (48%), Gaps = 11/97 (11%) Query: 714 AMNALRLEKAFRAWGLEMNCDTNPLEAGLEYFVKLN--KPADFIG------KQALKQIKA 765 ++ + L KA + L N D + + +++K+N P D+I L Q+ Sbjct: 229 SLRGIGLAKACKVLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVF 288 Query: 766 KGLKRRLVCLTLATDDVDPEGNESIWYNGKVVGNTTS 802 +KR+L+ L DDVDP E++ Y G+ V ++ + Sbjct: 289 DPIKRKLIPLNAYEDDVDP---ETLSYAGQYVDDSIA 322 >3ATQ-A nrPDB Length = 453 Score = 32.0 bits (71), Expect = 1.3, Method: Compositional matrix adjust. Identities = 26/82 (31%), Positives = 41/82 (50%), Gaps = 11/82 (13%) Query: 49 RAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKI 108 + + +IIGGG G S AY L++ G+K +LL S+ W+ G G + K Sbjct: 6 KYDVLIIGGGFAGSSAAYQLSRRGLK--ILLVDSK-----PWNRIGDKP---CGDAVSKA 55 Query: 109 HYDSIKL-YEKLEEETGQVVGF 129 H+D + + Y K EE ++ G Sbjct: 56 HFDKLGMPYPKGEELENKINGI 77 >2VVL-G nrPDB Length = 495 Score = 31.6 bits (70), Expect = 1.7, Method: Compositional matrix adjust. Identities = 19/57 (33%), Positives = 29/57 (50%), Gaps = 2/57 (3%) Query: 37 KPPLSAETQWKDRA-ETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHA 92 PP + E KD + ++IGGG G++ L AG K +LLE + G +W + Sbjct: 26 SPPTNIEDTDKDGPWDVIVIGGGYCGLTATRDLTVAGFK-TLLLEARDRIGGRSWSS 81 >3RHA-A nrPDB Length = 482 Score = 31.2 bits (69), Expect = 1.8, Method: Compositional matrix adjust. Identities = 16/40 (40%), Positives = 23/40 (57%), Gaps = 1/40 (2%) Query: 51 ETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTW 90 + VI+G G G++ A L KAG+ V +LE + G TW Sbjct: 9 DVVIVGAGPSGLTAARELKKAGLS-VAVLEARDRVGGRTW 47 >4IVM-B nrPDB Length = 483 Score = 31.2 bits (69), Expect = 1.9, Method: Compositional matrix adjust. Identities = 16/37 (43%), Positives = 24/37 (64%), Gaps = 1/37 (2%) Query: 52 TVIIGGGCVGVSLAYHLAKAGM-KDVVLLEKSELTAG 87 V++GGG G++ +YHL++A VVL+E SE G Sbjct: 11 VVVLGGGISGLAASYHLSRAPCPPKVVLVESSERLGG 47 >4UIR-A nrPDB Length = 646 Score = 31.2 bits (69), Expect = 1.9, Method: Compositional matrix adjust. Identities = 16/47 (34%), Positives = 25/47 (53%), Gaps = 3/47 (6%) Query: 45 QWKDRAETVIIGGGCVGVSLAYHLAKAG---MKDVVLLEKSELTAGS 88 Q D ++ IIG G G+S AY+ + G K++ LE+ + GS Sbjct: 58 QSYDNSKIYIIGSGIAGMSAAYYFIRDGHVPAKNITFLEQLHIDGGS 104 >1F8S-A nrPDB Length = 498 Score = 31.2 bits (69), Expect = 2.1, Method: Compositional matrix adjust. Identities = 18/35 (51%), Positives = 22/35 (62%), Gaps = 1/35 (2%) Query: 53 VIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAG 87 VI+G G G+S AY LA AG + V +LE SE G Sbjct: 37 VIVGAGMAGLSAAYVLAGAGHQ-VTVLEASERPGG 70 >1L1N-A nrPDB Length = 183 Score = 30.8 bits (68), Expect = 2.3, Method: Compositional matrix adjust. Identities = 16/41 (39%), Positives = 26/41 (63%), Gaps = 3/41 (7%) Query: 584 SHQSPGEFLLITGSGSELHDLRWIEEEAVKGGYDVEIKNIT 624 +H SPGE ++I G E+ D + +E++A G ++EI IT Sbjct: 39 THASPGESIVIDGKEVEILDAKALEDQA---GTNLEITIIT 76 >4K28-A nrPDB Length = 269 Score = 30.8 bits (68), Expect = 2.6, Method: Composition-based stats. Identities = 15/42 (35%), Positives = 24/42 (57%) Query: 53 VIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAG 94 ++IG G VG ++AY LA+AG+ + L + S G+ G Sbjct: 129 LVIGCGGVGSAIAYALAEAGIASITLCDPSTARMGAVCELLG 170 >2IUF-A nrPDB Length = 688 Score = 30.8 bits (68), Expect = 2.6, Method: Compositional matrix adjust. Identities = 22/75 (29%), Positives = 29/75 (38%), Gaps = 13/75 (17%) Query: 424 LIELDPNRYGKWTTTQYTEAKARESYGFNNIVGYPKEERFAGRPTQRVSGLYQRLESKCS 483 I LDPN Y T + + +A E+ G + F P + SG QR S Sbjct: 387 FIPLDPNAYSPNTENKGSPKQANETVG----------KGFFTAPERTASGKLQR---TLS 433 Query: 484 MGFHAGWEQPHWFYK 498 F W QP F+ Sbjct: 434 TTFENNWSQPRLFWN 448 >3RHC-A nrPDB Length = 113 Score = 30.4 bits (67), Expect = 3.3, Method: Compositional matrix adjust. Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 9/48 (18%) Query: 616 YDVEIKNITDELGV---------LGVAGPQARKVLQKLTSEDLSDDVF 654 Y E+K + LGV LG GPQ +KVL++LT + +VF Sbjct: 31 YCTEVKTLFKRLGVQPLVVELDQLGPQGPQLQKVLERLTGQHTVPNVF 78 >3R9U-A nrPDB Length = 315 Score = 30.4 bits (67), Expect = 3.7, Method: Compositional matrix adjust. Identities = 17/53 (32%), Positives = 29/53 (54%), Gaps = 3/53 (5%) Query: 51 ETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGI 103 + IIGGG G+S + + G+K+VV+ EK + G ++ + Y PG+ Sbjct: 6 DVAIIGGGPAGLSAGLYATRGGLKNVVMFEKG-MPGGQITSSSEIENY--PGV 55 >2IVE-A nrPDB Length = 478 Score = 30.4 bits (67), Expect = 3.7, Method: Compositional matrix adjust. Identities = 15/38 (39%), Positives = 22/38 (57%), Gaps = 1/38 (2%) Query: 52 TVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGST 89 ++GGG G+++A+HL G D VLLE S G+ Sbjct: 19 VAVVGGGISGLAVAHHLRSRG-TDAVLLESSARLGGAV 55 >4Y4M-A nrPDB Length = 290 Score = 30.4 bits (67), Expect = 3.9, Method: Compositional matrix adjust. Identities = 17/36 (47%), Positives = 22/36 (61%), Gaps = 2/36 (5%) Query: 45 QWKD--RAETVIIGGGCVGVSLAYHLAKAGMKDVVL 78 W D A+ VI+G G G++ A +LAK G K VVL Sbjct: 53 MWLDIVEADVVIVGAGPSGLTCARYLAKEGFKVVVL 88 >3UP5-A nrPDB Length = 545 Score = 30.0 bits (66), Expect = 5.1, Method: Compositional matrix adjust. Identities = 16/41 (39%), Positives = 25/41 (60%), Gaps = 2/41 (4%) Query: 51 ETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWH 91 + V+IG G G+ A+ + +AGMK V+ +E E G TW+ Sbjct: 11 DAVVIGAGVTGIYQAFLINQAGMK-VLGIEAGE-DVGGTWY 49 >1RP0-A nrPDB Length = 284 Score = 29.6 bits (65), Expect = 5.2, Method: Compositional matrix adjust. Identities = 13/40 (32%), Positives = 22/40 (55%) Query: 51 ETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTW 90 + V++G G G+S AY ++K V ++E+S G W Sbjct: 41 DVVVVGAGSAGLSAAYEISKNPNVQVAIIEQSVSPGGGAW 80 >5JMD-A nrPDB Length = 655 Score = 29.6 bits (65), Expect = 5.6, Method: Compositional matrix adjust. Identities = 12/33 (36%), Positives = 17/33 (51%) Query: 491 EQPHWFYKPGQDTQYRPSFRRTNWFEPVGSEYK 523 E +W Y P +D + R R WF P+G Y+ Sbjct: 100 EDINWQYWPVKDNELRWQLHRHKWFTPMGKAYR 132 >2CVJ-A nrPDB Length = 180 Score = 29.6 bits (65), Expect = 5.7, Method: Compositional matrix adjust. Identities = 13/28 (46%), Positives = 21/28 (75%) Query: 51 ETVIIGGGCVGVSLAYHLAKAGMKDVVL 78 + +++GGG G+S A LA+AG+K +VL Sbjct: 3 DVIVVGGGPSGLSAALFLARAGLKVLVL 30 >3RO8-A nrPDB Length = 341 Score = 29.6 bits (65), Expect = 5.9, Method: Compositional matrix adjust. Identities = 14/46 (30%), Positives = 22/46 (47%) Query: 498 KPGQDTQYRPSFRRTNWFEPVGSEYKQVMQRVAVTDLSPFGKFNIK 543 P Y+ S R+T W++ +GS+Y + A L +NIK Sbjct: 143 NPSNPADYKASLRQTPWYQAIGSDYVEQAFLAAREVLDENPSWNIK 188 >2GEY-A nrPDB Length = 158 Score = 29.6 bits (65), Expect = 6.0, Method: Composition-based stats. Identities = 25/117 (21%), Positives = 48/117 (41%), Gaps = 15/117 (12%) Query: 84 LTAGSTWHAAGLTTYFHPGI------------NLKKIHYDSIKLYEKLEEETGQVVGFHQ 131 + A + W +G+ ++ P I ++ K+ +K + L+ E ++ Sbjct: 14 VAAWNRWDLSGIIKHWSPDIVHYSEDNEVSSADMVKLMEGGLKAFPDLQLEVKSIMAEED 73 Query: 132 PGSIRLATTPVRVDEFK-YQMT--RTGWHATEQYLIEPEKIQEMFPLLNMNKVLAGL 185 ++R+ T EF Q T R WH E+ K+ E + ++NM +L L Sbjct: 74 RVALRITVTATHQGEFMGVQPTGQRVSWHLVEELRFVDGKVVEHWDVINMRPLLVRL 130 >3FZA-A nrPDB Length = 112 Score = 29.6 bits (65), Expect = 6.6, Method: Compositional matrix adjust. Identities = 17/48 (35%), Positives = 25/48 (52%), Gaps = 9/48 (18%) Query: 616 YDVEIKNITDELGV---------LGVAGPQARKVLQKLTSEDLSDDVF 654 Y E+K++ L V LG GPQ +KVL++LT + +VF Sbjct: 30 YSSEVKSLFKRLNVDPLVVELDELGAQGPQIQKVLERLTGQHTVPNVF 77 >1REO-A nrPDB Length = 486 Score = 29.6 bits (65), Expect = 6.6, Method: Compositional matrix adjust. Identities = 16/35 (45%), Positives = 22/35 (62%), Gaps = 1/35 (2%) Query: 53 VIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAG 87 V++G G G+S AY L+ AG + V +LE SE G Sbjct: 37 VVVGAGMSGLSAAYVLSGAGHQ-VTVLEASERAGG 70 >3LOV-A nrPDB Length = 475 Score = 29.3 bits (64), Expect = 7.0, Method: Compositional matrix adjust. Identities = 24/75 (32%), Positives = 37/75 (49%), Gaps = 8/75 (10%) Query: 53 VIIGGGCVGVSLAYHLAKAGMK-DVVLLEKSELTAG--STWHAAGLTTYFHPGINLKKIH 109 VI+GGG G++ AY+ +A ++ LLE E G +T+ G T P + + H Sbjct: 8 VIVGGGITGLAAAYYAERAFPDLNITLLEAGERLGGKVATYREDGFTIERGPDSYVARKH 67 Query: 110 -----YDSIKLYEKL 119 ++I L EKL Sbjct: 68 ILTDLIEAIGLGEKL 82 >3ISH-A nrPDB Length = 311 Score = 29.3 bits (64), Expect = 8.3, Method: Compositional matrix adjust. Identities = 13/31 (41%), Positives = 19/31 (61%) Query: 51 ETVIIGGGCVGVSLAYHLAKAGMKDVVLLEK 81 + IIGGG G+S + + G+K+ VL EK Sbjct: 3 DCAIIGGGPAGLSAGLYATRGGVKNAVLFEK 33 >4ND4-A nrPDB Length = 321 Score = 28.9 bits (63), Expect = 9.2, Method: Compositional matrix adjust. Identities = 13/36 (36%), Positives = 23/36 (63%) Query: 48 DRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSE 83 +R + +IG G +G ++AY + K + DVVL + +E Sbjct: 3 ERRKIAVIGSGQIGGNIAYIVGKDNLADVVLFDIAE 38 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5L46-A nrPDB 1208 0.0 4P9S-A nrPDB 1164 0.0 1PJ5-A nrPDB 828 0.0 1YX2-A nrPDB 408 e-114 2GAG-B nrPDB 398 e-111 1WOR-A nrPDB 395 e-110 1V5V-A nrPDB 392 e-109 3AD9-B nrPDB 361 e-100 3GIR-A nrPDB 355 5e-98 3BHF-A nrPDB 354 1e-97 1WSR-A nrPDB 352 3e-97 2GAG-A nrPDB 339 2e-93 3A8J-A nrPDB 339 3e-93 1VRQ-A nrPDB 334 1e-91 1ZOV-A nrPDB 329 5e-90 3TFJ-A nrPDB 328 8e-90 1NG3-A nrPDB 304 1e-82 3SM8-A nrPDB 264 1e-70 4YSH-A nrPDB 256 4e-68 Sequences not found previously or not previously below threshold: 2UZZ-A nrPDB 171 1e-42 5X1I-A nrPDB 109 4e-24 5XAO-A nrPDB 95 1e-19 3VQR-A nrPDB 80 4e-15 3PS9-A nrPDB 59 7e-09 3PVC-A nrPDB 57 4e-08 5EZ7-A nrPDB 55 1e-07 3DA1-A nrPDB 51 2e-06 1QO8-A nrPDB 51 3e-06 5KOX-A nrPDB 49 7e-06 1D4E-A nrPDB 47 2e-05 2RGO-A nrPDB 47 3e-05 2RGH-A nrPDB 47 4e-05 1KNR-A nrPDB 46 7e-05 1RP0-A nrPDB 45 1e-04 3CUK-A nrPDB 45 1e-04 1F8S-A nrPDB 44 2e-04 3R9U-A nrPDB 44 3e-04 3ISH-A nrPDB 44 4e-04 1VE9-A nrPDB 44 4e-04 4REP-A nrPDB 44 4e-04 3KVE-A nrPDB 43 4e-04 6BRD-A nrPDB 43 6e-04 5MJK-A nrPDB 42 8e-04 4DGK-A nrPDB 42 0.001 5KXJ-A nrPDB 42 0.001 2CVJ-A nrPDB 42 0.001 1NRK-A nrPDB 41 0.002 1C0L-A nrPDB 41 0.002 1NAA-A nrPDB 41 0.002 3ATQ-A nrPDB 41 0.002 5NCC-A nrPDB 41 0.003 3FPZ-A nrPDB 41 0.003 4C5O-A nrPDB 40 0.004 3MJ4-A nrPDB 40 0.004 3WE0-A nrPDB 40 0.005 3L1R-A nrPDB 40 0.005 4Y4M-A nrPDB 39 0.006 1REO-A nrPDB 39 0.006 4IV9-A nrPDB 39 0.006 2JB2-A nrPDB 39 0.006 5MOG-A nrPDB 39 0.012 4K5R-A nrPDB 39 0.012 1SEZ-A nrPDB 39 0.013 1KSU-A nrPDB 38 0.014 3IHG-A nrPDB 38 0.015 4UIR-A nrPDB 38 0.015 4BK3-A nrPDB 38 0.017 4EIQ-A nrPDB 37 0.025 3CGD-A nrPDB 37 0.026 3BI4-A nrPDB 37 0.027 2IVE-A nrPDB 37 0.028 5UWY-A nrPDB 37 0.031 5MH6-A nrPDB 37 0.032 4K2X-A nrPDB 37 0.036 2BXR-A nrPDB 37 0.037 1O5W-A nrPDB 37 0.043 5ZYN-B nrPDB 37 0.043 1MDA-H nrPDB 37 0.046 3RHA-A nrPDB 37 0.050 6CR0-A nrPDB 36 0.051 3ABT-A nrPDB 36 0.053 4Z2R-A nrPDB 36 0.054 2E5V-A nrPDB 36 0.062 4Y4N-A nrPDB 36 0.070 2VVL-G nrPDB 36 0.075 4RPJ-A nrPDB 36 0.080 5L3D-A nrPDB 36 0.095 4B1B-A nrPDB 36 0.10 3UP5-A nrPDB 36 0.10 4USR-A nrPDB 36 0.11 4ZN0-A nrPDB 36 0.11 2CUL-A nrPDB 35 0.11 3JSK-A nrPDB 35 0.12 6EZS-A nrPDB 35 0.12 6N7F-A nrPDB 35 0.12 3LOV-A nrPDB 35 0.13 1JWB-B nrPDB 35 0.14 3NK2-X nrPDB 35 0.15 4X4J-A nrPDB 35 0.16 2GMH-A nrPDB 35 0.17 4HA6-A nrPDB 34 0.20 5TUK-A nrPDB 34 0.23 2Q7V-A nrPDB 34 0.25 4NTC-A nrPDB 34 0.26 2WOV-A nrPDB 34 0.28 3VH2-A nrPDB 34 0.32 3T7E-A nrPDB 34 0.32 4GCM-A nrPDB 34 0.32 4Z25-A nrPDB 34 0.36 2HQM-A nrPDB 34 0.41 5TUM-A nrPDB 33 0.46 4JNQ-A nrPDB 33 0.48 5EQD-A nrPDB 33 0.48 1UXJ-A nrPDB 33 0.49 4MOP-A nrPDB 33 0.57 1FEC-A nrPDB 33 0.61 4IA5-A nrPDB 33 0.64 1V59-A nrPDB 33 0.64 5Z70-A nrPDB 33 0.66 4OEN-A nrPDB 33 0.69 4K22-A nrPDB 33 0.69 3G5Q-A nrPDB 32 0.75 4N9X-A nrPDB 32 0.75 1CSN-A nrPDB 32 0.75 4OVI-A nrPDB 32 0.77 3WSV-A nrPDB 32 0.80 1I8T-A nrPDB 32 0.80 6C6P-A nrPDB 32 0.83 4IVM-B nrPDB 32 0.85 2NVK-X nrPDB 32 0.85 4NEW-A nrPDB 32 0.96 2A9F-A nrPDB 32 1.0 4YNU-A nrPDB 32 1.1 4LBU-A nrPDB 32 1.1 3DL2-A nrPDB 32 1.1 5BR7-A nrPDB 32 1.2 4UDQ-A nrPDB 32 1.2 5CEE-A nrPDB 32 1.6 4MO2-B nrPDB 32 1.6 3Q6J-A nrPDB 31 1.7 2ZBW-A nrPDB 31 1.7 1PS9-A nrPDB 31 1.7 2X3N-A nrPDB 31 1.8 5TUF-A nrPDB 31 1.9 2QA1-A nrPDB 31 2.0 4AP1-A nrPDB 31 2.0 5EVY-X nrPDB 31 2.2 1DOD-A nrPDB 31 2.3 6QE4-A nrPDB 31 2.3 3RED-A nrPDB 31 2.9 3EOQ-A nrPDB 31 3.0 4B3J-A nrPDB 31 3.1 1MAF-H nrPDB 31 3.5 2RGJ-A nrPDB 31 3.5 5W4C-A nrPDB 30 4.0 6AH0-2 nrPDB 30 4.4 5JCN-A nrPDB 30 4.7 6ER9-A nrPDB 30 5.2 >5L46-A nrPDB Length = 841 Score = 1208 bits (3126), Expect = 0.0, Method: Composition-based stats. Identities = 837/838 (99%), Positives = 837/838 (99%) Query: 29 VCGREGEEKPPLSAETQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGS 88 VCGREGEEKPPLSAETQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGS Sbjct: 2 VCGREGEEKPPLSAETQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGS 61 Query: 89 TWHAAGLTTYFHPGINLKKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFK 148 TWHAAGLTTYFHPGINLKKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFK Sbjct: 62 TWHAAGLTTYFHPGINLKKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFK 121 Query: 149 YQMTRTGWHATEQYLIEPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARK 208 YQMTRTGWHATEQYLIEPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARK Sbjct: 122 YQMTRTGWHATEQYLIEPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARK 181 Query: 209 CGALLKYPAPVTSLKARSDGTWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPV 268 CGALLKYPAPVTSLKARSDGTWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPV Sbjct: 182 CGALLKYPAPVTSLKARSDGTWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPV 241 Query: 269 QHQYVVTSTISEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNG 328 QHQYVVTSTI EVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNG Sbjct: 242 QHQYVVTSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNG 301 Query: 329 VPPGFGKELFESDLDRIMEHIKAAMEMVPVLKKADIINVVNGPITYSPDILPMVGPHQGV 388 VPPGFGKELFESDLDRIMEHIKAAMEMVPVLKKADIINVVNGPITYSPDILPMVGPHQGV Sbjct: 302 VPPGFGKELFESDLDRIMEHIKAAMEMVPVLKKADIINVVNGPITYSPDILPMVGPHQGV 361 Query: 389 RNYWVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARES 448 RNYWVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARES Sbjct: 362 RNYWVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARES 421 Query: 449 YGFNNIVGYPKEERFAGRPTQRVSGLYQRLESKCSMGFHAGWEQPHWFYKPGQDTQYRPS 508 YGFNNIVGYPKEERFAGRPTQRVSGLYQRLESKCSMGFHAGWEQPHWFYKPGQDTQYRPS Sbjct: 422 YGFNNIVGYPKEERFAGRPTQRVSGLYQRLESKCSMGFHAGWEQPHWFYKPGQDTQYRPS 481 Query: 509 FRRTNWFEPVGSEYKQVMQRVAVTDLSPFGKFNIKGQDSIRLLDHLFANVIPKVGFTNIS 568 FRRTNWFEPVGSEYKQVMQRVAVTDLSPFGKFNIKGQDSIRLLDHLFANVIPKVGFTNIS Sbjct: 482 FRRTNWFEPVGSEYKQVMQRVAVTDLSPFGKFNIKGQDSIRLLDHLFANVIPKVGFTNIS 541 Query: 569 HMLTPKGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEEAVKGGYDVEIKNITDELG 628 HMLTPKGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEEAVKGGYDVEIKNITDELG Sbjct: 542 HMLTPKGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEEAVKGGYDVEIKNITDELG 601 Query: 629 VLGVAGPQARKVLQKLTSEDLSDDVFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHRR 688 VLGVAGPQARKVLQKLTSEDLSDDVFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHRR Sbjct: 602 VLGVAGPQARKVLQKLTSEDLSDDVFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHRR 661 Query: 689 EDSVALYDAIMNAGQEEGIDNFGTYAMNALRLEKAFRAWGLEMNCDTNPLEAGLEYFVKL 748 EDSVALYDAIMNAGQEEGIDNFGTYAMNALRLEKAFRAWGLEMNCDTNPLEAGLEYFVKL Sbjct: 662 EDSVALYDAIMNAGQEEGIDNFGTYAMNALRLEKAFRAWGLEMNCDTNPLEAGLEYFVKL 721 Query: 749 NKPADFIGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESIWYNGKVVGNTTSGSYSYS 808 NKPADFIGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESIWYNGKVVGNTTSGSYSYS Sbjct: 722 NKPADFIGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESIWYNGKVVGNTTSGSYSYS 781 Query: 809 IQKSLAFAYVPVQLSEVGQQVEVELLGKNYPAVIIQEPLVLTEPTRNRLQKKGGKDKT 866 IQKSLAFAYVPVQLSEVGQQVEVELLGKNYPAVIIQEPLVLTEPTRNRLQKKGGKDKT Sbjct: 782 IQKSLAFAYVPVQLSEVGQQVEVELLGKNYPAVIIQEPLVLTEPTRNRLQKKGGKDKT 839 >4P9S-A nrPDB Length = 848 Score = 1164 bits (3011), Expect = 0.0, Method: Composition-based stats. Identities = 765/832 (91%), Positives = 798/832 (95%), Gaps = 2/832 (0%) Query: 32 REGEEKPPLSAETQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWH 91 REG+E PP +WKDRAETVIIGGGCVGVSLAYHLAKAGM+DVVLLEKSELTAGSTWH Sbjct: 8 REGQESPPSP--PEWKDRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTWH 65 Query: 92 AAGLTTYFHPGINLKKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQM 151 AAGLTTYFHPGINLKKIHYDSIKLYE+LEEETGQVVGFHQPGSIRLATTP RVDEFKYQM Sbjct: 66 AAGLTTYFHPGINLKKIHYDSIKLYERLEEETGQVVGFHQPGSIRLATTPERVDEFKYQM 125 Query: 152 TRTGWHATEQYLIEPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGA 211 TRT WHATEQY+IEPEKI E+FPLLNM+K+LAGLYNPGDGHIDPYSLTMALA GARK GA Sbjct: 126 TRTNWHATEQYIIEPEKIHELFPLLNMDKILAGLYNPGDGHIDPYSLTMALATGARKYGA 185 Query: 212 LLKYPAPVTSLKARSDGTWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQ 271 LLKYPAPVTSLK R DGTWDVETPQGS+RANRIVNAAGFWAREVGKMIGL+HPLIPVQHQ Sbjct: 186 LLKYPAPVTSLKPRPDGTWDVETPQGSVRANRIVNAAGFWAREVGKMIGLDHPLIPVQHQ 245 Query: 272 YVVTSTISEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNGVPP 331 YV+TSTI EVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMK+Q SWV +GVPP Sbjct: 246 YVITSTIPEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKLQASWVAHGVPP 305 Query: 332 GFGKELFESDLDRIMEHIKAAMEMVPVLKKADIINVVNGPITYSPDILPMVGPHQGVRNY 391 GFGKELFESDLDRI EH++AAMEMVPVLKKADIIN+VNGPITYSPDILPMVGPHQGVRNY Sbjct: 306 GFGKELFESDLDRITEHVEAAMEMVPVLKKADIINIVNGPITYSPDILPMVGPHQGVRNY 365 Query: 392 WVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARESYGF 451 WVAIGFGYGIIHAGGVG YLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARESYGF Sbjct: 366 WVAIGFGYGIIHAGGVGTYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARESYGF 425 Query: 452 NNIVGYPKEERFAGRPTQRVSGLYQRLESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRR 511 NNIVGYPKEERFAGRPTQRVSGLY+ LESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRR Sbjct: 426 NNIVGYPKEERFAGRPTQRVSGLYKILESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRR 485 Query: 512 TNWFEPVGSEYKQVMQRVAVTDLSPFGKFNIKGQDSIRLLDHLFANVIPKVGFTNISHML 571 TNWFEPVGSEYKQVMQRV V DLSPFGKFNIKGQDS +LLDHL ANVIPKVGFTNISHML Sbjct: 486 TNWFEPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDSTQLLDHLCANVIPKVGFTNISHML 545 Query: 572 TPKGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEEAVKGGYDVEIKNITDELGVLG 631 TP+GRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEE AV+GGYDVEI+NITDELGVLG Sbjct: 546 TPRGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEAAVRGGYDVEIRNITDELGVLG 605 Query: 632 VAGPQARKVLQKLTSEDLSDDVFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHRREDS 691 VAGP AR+VLQKLTSEDLSDDVFKFLQTKSLK+S+IPVTAIRISYTGELGWELYHRREDS Sbjct: 606 VAGPYARRVLQKLTSEDLSDDVFKFLQTKSLKISDIPVTAIRISYTGELGWELYHRREDS 665 Query: 692 VALYDAIMNAGQEEGIDNFGTYAMNALRLEKAFRAWGLEMNCDTNPLEAGLEYFVKLNKP 751 ALY+ IMNAGQEEGIDNFGTYA+NALRLEKAFRAWG EMNCDTNPLEAGL+YF+KLNKP Sbjct: 666 AALYERIMNAGQEEGIDNFGTYALNALRLEKAFRAWGSEMNCDTNPLEAGLDYFIKLNKP 725 Query: 752 ADFIGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESIWYNGKVVGNTTSGSYSYSIQK 811 A+F GKQALKQIKAKGLKRRLVCLTLATD+VDPEGNES+WY GKV+GNTTSGSYSYSIQK Sbjct: 726 ANFTGKQALKQIKAKGLKRRLVCLTLATDNVDPEGNESVWYKGKVIGNTTSGSYSYSIQK 785 Query: 812 SLAFAYVPVQLSEVGQQVEVELLGKNYPAVIIQEPLVLTEPTRNRLQKKGGK 863 SLAFAYVPV+LSEVGQQVEVELLGKNYPA IIQEPLVLTEPTR RLQK G K Sbjct: 786 SLAFAYVPVELSEVGQQVEVELLGKNYPATIIQEPLVLTEPTRTRLQKDGRK 837 >1PJ5-A nrPDB Length = 830 Score = 828 bits (2138), Expect = 0.0, Method: Composition-based stats. Identities = 242/835 (28%), Positives = 406/835 (48%), Gaps = 42/835 (5%) Query: 52 TVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSEL--TAGSTWHAAGLTTYFHPGINLKKIH 109 VIIG G VG +LA L G ++ +L++ L GST HA GL +P + Sbjct: 7 IVIIGAGIVGTNLADELVTRGWNNITVLDQGPLNMPGGSTSHAPGLVFQTNPSKTMASFA 66 Query: 110 YDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLIEPEKI 169 +++ L E+ V F+Q G + +ATT R+ + K ++ E L+ P + Sbjct: 67 KYTVEKLLSLTED--GVSCFNQVGGLEVATTETRLADLKRKLGYAAAWGIEGRLLSPAEC 124 Query: 170 QEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARSDGT 229 QE++PLL+ +L GL+ P DG L G + VT ++ Sbjct: 125 QELYPLLDGENILGGLHVPSDGLASAARAVQLLIKRTESAGVTYRGSTTVTGIEQSGGRV 184 Query: 230 WDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYVVTSTISEVKALKRE-- 287 V+T G + A+ +V+ AGFW ++G MIG+ PL+P+ HQYV T+ + + + Sbjct: 185 TGVQTADGVIPADIVVSCAGFWGAKIGAMIGMAVPLLPLAHQYVKTTPVPAQQGRNDQPN 244 Query: 288 ---LPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNGVPPGFGKELFESDLDR 344 LP+LR + Y R+ D G Y + M V + P + S LD Sbjct: 245 GARLPILRHQDQDLYYREHGDRYGIGSY-AHRPMPVDVDTLGAYAPETVSEHHMPSRLDF 303 Query: 345 IMEHI----KAAMEMVPVLKKADIINVVNGPITYSPDILPMVGPHQGVRNYWVAIGFGYG 400 +E +A +++P L ++I + NG +++PD P++G + + ++VA Sbjct: 304 TLEDFLPAWEATKQLLPALADSEIEDGFNGIFSFTPDGGPLLGESKELDGFYVAEAVW-- 361 Query: 401 IIHAGGVGKYLSDWILHGEPPFDLIELDPNRYGK-WTTTQYTEAKARESYGFNNIVGYPK 459 + H+ GV K +++ + G DL E D R+ T +Y +++++ V +P Sbjct: 362 VTHSAGVAKAMAELLTTGRSETDLGECDITRFEDVQLTPEYVSETSQQNFVEIYDVLHPL 421 Query: 460 EERFAGRPTQRVSGLYQRLESKCSMGFHA-GWEQPHWFYKPGQDTQYRPSFRRTNWFEPV 518 + R + R RVS + R + + A GWE+P+WF + P+ W P Sbjct: 422 QPRLSPR-NLRVSPFHARHKELGAFFLEAGGWERPYWFEANAALLKEMPA----EWLPPA 476 Query: 519 GS-------------EYKQVMQRVAVTDLSPFGKFNIKGQDSIRLLDHLFANVIP-KVGF 564 E + VA+ D++P + + G +++LL L + K G Sbjct: 477 RDAWSGMFSSPIAAAEAWKTRTAVAMYDMTPLKRLEVSGPGALKLLQELTTADLAKKPGA 536 Query: 565 TNISHMLTPKGRVYAELTVSHQSPGEFLL-ITGSGSELHDLRWIEEEAVKGGYD--VEIK 621 + +L G V +++TV+ S F L G+ + R + G V+++ Sbjct: 537 VTYTLLLDHAGGVRSDITVARLSEDTFQLGANGNIDTAYFERAARHQTQSGSATDWVQVR 596 Query: 622 NITDELGVLGVAGPQARKVLQKLTSEDLSDDVFKFLQTKSLKVSNIPVTAIRISYTGELG 681 + T +G+ GP AR ++ K++ +D ++D K+ + K++ + IPVTA+R+SY GELG Sbjct: 597 DTTGGTCCIGLWGPLARDLVSKVSDDDFTNDGLKYFRAKNVVIGGIPVTAMRLSYVGELG 656 Query: 682 WELYHRREDSVALYDAIMNAGQEEGIDNFGTYAMNALRLEKAFRAWGLEMNCDTNPLEAG 741 WELY ++ L+DA+ AGQ G+ G A ++LRLEK +R+WG +M + +P EAG Sbjct: 657 WELYTSADNGQRLWDALWQAGQPFGVIAAGRAAFSSLRLEKGYRSWGTDMTTEHDPFEAG 716 Query: 742 LEYFVKLNKPADFIGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESIWYNGKVVGNTT 801 L + VK+ K + FIGK AL+ + RRL CLT+ G E ++Y + VG T Sbjct: 717 LGFAVKMAKES-FIGKGALEGRTEEASARRLRCLTIDDGRSIVLGKEPVFYKEQAVGYVT 775 Query: 802 SGSYSYSIQKSLAFAYVPVQLSEVGQQVEVELLGKNYPAVIIQEPLVLTEPTRNR 856 S +Y Y++ K +A++Y+P +S VG V++E G+ A + ++PL + TR R Sbjct: 776 SAAYGYTVAKPIAYSYLPGTVS-VGDSVDIEYFGRRITATVTEDPLYDPKMTRLR 829 >1YX2-A nrPDB Length = 365 Score = 408 bits (1049), Expect = e-114, Method: Composition-based stats. Identities = 110/383 (28%), Positives = 178/383 (46%), Gaps = 28/383 (7%) Query: 469 QRVSGLYQRLESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFEPVGSEYKQVMQR 528 +R E GWE P F + E++ V Sbjct: 6 KRTPLFDLYKEYGGKTIDFGGWELPVQ-------------------FSSIKKEHEAVRTA 46 Query: 529 VAVTDLSPFGKFNIKGQDSIRLLDHLFANVIPK--VGFTNISHMLTPKGRVYAELTVSHQ 586 + D+S G+ + G DS+ L L N + G + M P G +L + + Sbjct: 47 AGLFDVSHMGEVEVSGNDSLSFLQRLMTNDVSALTPGRAQYTAMCYPDGGTVDDLLIYQK 106 Query: 587 SPGEFLLITGSGSELHDLRWIEEEAVKGGYDVEIKNITDELGVLGVAGPQARKVLQKLTS 646 +LL+ + + DL W++E A DV+I N +D++ +L V GP+A +L+ LT Sbjct: 107 GENRYLLVINASNIDKDLAWMKEHAAG---DVQIDNQSDQIALLAVQGPKAEAILKNLTD 163 Query: 647 EDLSD-DVFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHRREDSVALYDAIMNAGQEE 705 D+S F F+ +S R YTGE G+E+Y R +D++ ++ I++AG Sbjct: 164 ADVSALKPFAFIDEAD--ISGRKALISRTGYTGEDGYEIYCRSDDAMHIWKKIIDAGDAY 221 Query: 706 GIDNFGTYAMNALRLEKAFRAWGLEMNCDTNPLEAGLEYFVKLNKPADFIGKQALKQIKA 765 G+ G A + LR E +G E+ D P+EAG+ + VK K +DF GK L + K Sbjct: 222 GLIPCGLGARDTLRFEANIPLYGQELTRDITPIEAGIGFAVKHKKESDFFGKSVLSEQKE 281 Query: 766 KGLKRRLVCLTLATDDVDPEGNESIWYNGKVVGNTTSGSYSYSIQKSLAFAYVPVQLSEV 825 G KR+LV L + + G E ++ NGK VG T+G+ S ++ K++ A + + SE+ Sbjct: 282 NGAKRKLVGLEMIEKGIPRHGYE-VFQNGKSVGKVTTGTQSPTLGKNVGLALIDSETSEI 340 Query: 826 GQQVEVELLGKNYPAVIIQEPLV 848 G V+VE+ K A +++ P Sbjct: 341 GTVVDVEIRKKLVKAKVVKTPFY 363 >2GAG-B nrPDB Length = 405 Score = 398 bits (1022), Expect = e-111, Method: Composition-based stats. Identities = 89/401 (22%), Positives = 166/401 (41%), Gaps = 29/401 (7%) Query: 40 LSAETQWKDRAETVIIGGGCVGVSLAYHLAK-AGMKDVVLLEKSELTAGSTWHAAGLTTY 98 L A + K + +I+GGG G++ AY LAK G+ +V +LEK L G+ + Sbjct: 12 LWANPEPKKSYDAIIVGGGGHGLATAYFLAKNHGITNVAVLEKGWLAGGNMARNTTIIRS 71 Query: 99 FHPGINLKKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHA 158 + I+ S+KL+E+L E+ F Q G + LA T V E ++ + Sbjct: 72 NYLWDESAGIYEKSLKLWEQLPEDLEYDFLFSQRGVLNLAHTLGDVRESVRRVEANKLNG 131 Query: 159 TEQYLIEPEKIQEMFPLLNMNK-----VLAGLYNPGDGHIDPYSLTMALAAGARKCGALL 213 + ++P +++E P++N + V+ + P G + A A A + G + Sbjct: 132 VDAEWLDPSQVKEACPIINTSDDIRYPVMGATWQPRAGIAKHDHVAWAFARKANEMGVDI 191 Query: 214 KYPAPVTSLKARSDGTWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYV 273 VT + V+T +G++ A ++ A + + +M G E P+ + Sbjct: 192 IQNCEVTGFIKDGEKVTGVKTTRGTIHAGKVALAGAGHSSVLAEMAGFELPIQ----SHP 247 Query: 274 VTSTISEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNGVPPGF 333 + + +SE+ V+ + Y + + L+ G DS+ G+ Sbjct: 248 LQALVSELFEPVHPTVVMSNHIHVYVSQAHKGELVMG--------AGIDSY------NGY 293 Query: 334 GKELFESDLDRIMEHIKAAMEMVPVLKKADIINVVNGPITYSPDILPMVGPHQGVRNYWV 393 G+ I E + AA+E+ P+ +A ++ G + + D P++ ++N +V Sbjct: 294 GQ---RGAFHVIQEQMAAAVELFPIFARAHVLRTWGGIVDTTMDASPIISK-TPIQNLYV 349 Query: 394 AIGFGYGIIHA-GGVGKYLSDWILHGEPPFDLIELDPNRYG 433 G+G G G G L+ I + EP R+ Sbjct: 350 NCGWGTGGFKGTPGAGFTLAHTIANDEPHELNKPFSLERFE 390 >1WOR-A nrPDB Length = 364 Score = 395 bits (1014), Expect = e-110, Method: Composition-based stats. Identities = 117/386 (30%), Positives = 196/386 (50%), Gaps = 35/386 (9%) Query: 469 QRVSGLYQRLESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFEPVGSEYKQVMQR 528 +R + +E M AGWE P ++ + E V + Sbjct: 2 KRTPLFEKHVELGAKMVDFAGWEMPLYY-------------------TSIFEEVMAVRKS 42 Query: 529 VAVTDLSPFGKFNIKGQDSIRLLDHLFANVIPKV--GFTNISHMLTPKGRVYAELTVSHQ 586 V + D+S G+F +KG +++ +D L N + G S M G + +L V Sbjct: 43 VGMFDVSHMGEFLVKGPEAVSFIDFLITNDFSSLPDGKAIYSVMCNENGGIIDDLVVYKV 102 Query: 587 SPGEFLLITGSGSELHDLRWIEEEAVKGGYDVEIKNITDELGVLGVAGPQARKVLQKLTS 646 SP E L++ + + D WI+ + +DVE+ NI+D ++ GP+A++ LQ+L Sbjct: 103 SPDEALMVVNAANIEKDFNWIKSHS--KNFDVEVSNISDTTALIAFQGPKAQETLQELV- 159 Query: 647 EDLSDDVFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHRREDSVALYDAIMNAGQEEG 706 ED +++ + KS+ V+ + R YTGE G+EL +++ ++DA+MN ++ Sbjct: 160 EDGLEEIAYYSFRKSI-VAGVETLVSRTGYTGEDGFELMLEAKNAPKVWDALMNLLRKID 218 Query: 707 IDNFGTYAMNALRLEKAFRAWGLEMNCDTNPLEAGLEYFVKLNKPADFIGKQALKQIKAK 766 G A + RLE + +G +M+ +TNP E GL + VKLNK DF+GK+AL + K K Sbjct: 219 GRPAGLGARDVCRLEATYLLYGQDMDENTNPFEVGLSWVVKLNK--DFVGKEALLKAKEK 276 Query: 767 GLKRRLVCLTLATDDVDPEGNESIWYNGKVVGNTTSGSYSYSIQKSLAFAYVPVQLSEVG 826 ++R+LV L L+ + +G E + NG+ VG TSG++S ++ KS+A A V + ++G Sbjct: 277 -VERKLVALELSGKRIARKGYE-VLKNGERVGEITSGNFSPTLGKSIALALVSKSV-KIG 333 Query: 827 QQVEVELLGKNYPAVIIQEPLVLTEP 852 Q LG +P + E LV+ +P Sbjct: 334 DQ-----LGVVFPGGKLVEALVVKKP 354 >1V5V-A nrPDB Length = 401 Score = 392 bits (1007), Expect = e-109, Method: Composition-based stats. Identities = 102/414 (24%), Positives = 187/414 (45%), Gaps = 57/414 (13%) Query: 469 QRVSGLYQRLESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFEPVGSEYKQVMQR 528 +RV E + AGWE P W+ + E+ V Sbjct: 6 KRVHIFDWHKEHARKIEEFAGWEMPIWY-------------------SSIKEEHLAVRNA 46 Query: 529 VAVTDLSPFGKFNIKGQDSIRLLDHLFANVIPKVGF--TNISHMLTPKGRVYAELTVSHQ 586 V + D+S G+ +G+D+++ L ++ N I K + +L +G + E V + Sbjct: 47 VGIFDVSHMGEIVFRGKDALKFLQYVTTNDISKPPAISGTYTLVLNERGAIKDETLVFNM 106 Query: 587 SPGEFLLITGSGSELHDLRWIE------EEAVKGGYDVEIKNITDELGVLGVAGPQARKV 640 E+L+I S + W E+ K ++E+K T ++ + V GP+AR + Sbjct: 107 GNNEYLMICDSDAFEKLYAWFTYLKRTIEQFTKLDLEIELK--TYDIAMFAVQGPKARDL 164 Query: 641 LQKLTSEDLSDDVFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHRR------------ 688 + L D+++ + Q + +++ I + R YTGE G+E+Y Sbjct: 165 AKDLFGIDINE--MWWFQARWVELDGIKMLLSRSGYTGENGFEVYIEDANPYHPDESKRG 222 Query: 689 --EDSVALYDAIMNAGQEEGIDNFGTYAMNALRLEKAFRAWGLEMNC---------DTNP 737 E ++ +++ I+ G++ GI G A + LRLE + +G E + P Sbjct: 223 EPEKALHVWERILEEGKKYGIKPCGLGARDTLRLEAGYTLYGNETKELQLLSTDIDEVTP 282 Query: 738 LEAGLEYFVKLNKPADFIGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESIWYNGKVV 797 L+A LE+ + +K DFIGK AL + K +G+ R+LV + + EG + ++ NG+++ Sbjct: 283 LQANLEFAIYWDK--DFIGKDALLKQKERGVGRKLVHFKMIDKGIPREGYK-VYANGEMI 339 Query: 798 GNTTSGSYSYSIQKSLAFAYVPVQLSEVGQQVEVELLGKNYPAVIIQEPLVLTE 851 G TSG+ S + + A+V + ++ G ++EVE+ G+ AV + P + Sbjct: 340 GEVTSGTLSPLLNVGIGIAFVKEEYAKPGIEIEVEIRGQRKKAVTVTPPFYDPK 393 >3AD9-B nrPDB Length = 404 Score = 361 bits (926), Expect = e-100, Method: Composition-based stats. Identities = 92/401 (22%), Positives = 167/401 (41%), Gaps = 29/401 (7%) Query: 40 LSAETQWKDRAETVIIGGGCVGVSLAYHLAK-AGMKDVVLLEKSELTAGSTWHAAGLTTY 98 L + K + VI+GGG G++ AY+LAK G+ +V +LEK L G+ + Sbjct: 11 LWNNPEPKKSYDVVIVGGGGHGLATAYYLAKNHGITNVAVLEKGWLAGGNMARNTTIIRS 70 Query: 99 FHPGINLKKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHA 158 + I+ S+KL+E+L EE F Q G + LA T V E ++ ++ Sbjct: 71 NYLWDESAGIYEKSLKLWEELPEELEYDFLFSQRGVLNLAHTLGDVRESIRRVEANKFNG 130 Query: 159 TEQYLIEPEKIQEMFPLLNMNK-----VLAGLYNPGDGHIDPYSLTMALAAGARKCGALL 213 + + PE+++E+ P++N V+ Y P G + A A A + G + Sbjct: 131 VDAEWLTPEQVKEVCPIINTGDNIRYPVMGATYQPRAGIAKHDHVAWAFARKANEMGVDI 190 Query: 214 KYPAPVTSLKARSDGTWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYV 273 VT + V+T +G++ A ++ A + + ++ G E P+ + Sbjct: 191 IQNCEVTGFLKDGEKVTGVKTTRGTILAGKVALAGAGHSSVLAELAGFELPIQ----SHP 246 Query: 274 VTSTISEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNGVPPGF 333 + + +SE+ V+ + Y + + L+ G DS+ G+ Sbjct: 247 LQALVSELFEPVHPTVVMSNHIHVYVSQAHKGELVMG--------AGIDSY------NGY 292 Query: 334 GKELFESDLDRIMEHIKAAMEMVPVLKKADIINVVNGPITYSPDILPMVGPHQGVRNYWV 393 G+ I E + AA+E+ P+ +A ++ G + + D P++ ++N +V Sbjct: 293 GQ---RGAFHVIEEQMAAAVELFPIFARAHVLRTWGGIVDTTMDASPIISK-TPIQNLYV 348 Query: 394 AIGFGYGIIHA-GGVGKYLSDWILHGEPPFDLIELDPNRYG 433 G+G G G G L+ I H EP R+ Sbjct: 349 NCGWGTGGFKGTPGAGYTLAHTIAHDEPHKLNAPFALERFE 389 >3GIR-A nrPDB Length = 393 Score = 355 bits (910), Expect = 5e-98, Method: Composition-based stats. Identities = 91/395 (23%), Positives = 154/395 (38%), Gaps = 35/395 (8%) Query: 461 ERFAGRPTQRVSGLYQRLESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFEPVGS 520 + F + + ++ G AGW P + V Sbjct: 26 QEFETSSLKTLPLYELHEKAGAKFGAFAGWRMPLTYP------------------LGVLK 67 Query: 521 EYKQVMQRVAVTDLSPFGKFNIKGQDSIRLLDHLFANV--IPKVGFTNISHMLTPKGRVY 578 E+ + D+S ++G ++ L + + K+G + S++L + + Sbjct: 68 EHLHTRAHAGLFDISHMKLIAVEGPKAVEFLSYALPVDAALLKIGQSRYSYLLNERAGIL 127 Query: 579 AELTVSHQSPGEFLLITGSGSELHDLRWIEEEAVKGGYDVEIKNITDELGVLGVAGPQAR 638 +L ++ + F+L+ +G+ D +E+ A + E + I E +L + GPQA Sbjct: 128 DDLILTRLAECRFMLVANAGNAQADFAELEKRA----FGFECQVIALERVLLALQGPQAA 183 Query: 639 KVLQKLTSEDLSDDVFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHRREDSVALYDAI 698 V L L + F+Q + + +T R YTGE G+E+ + AL + + Sbjct: 184 AV---LADAGLPGNELLFMQGFEPQ-QDWFIT--RSGYTGEDGFEIALPIGCARALAEKL 237 Query: 699 MNAGQEEGIDNFGTYAMNALRLEKAFRAWGLEMNCDTNPLEAGLEYFVKLN--KPADFIG 756 + + E + G A ++LRLE G ++ DT P++A L + V N + A F G Sbjct: 238 LGDSRVEWV---GLAARDSLRLEAGLCLHGNDITPDTTPIDAALTWAVPKNVREKAQFYG 294 Query: 757 KQALKQIKAKGLKRRLVCLTLATDDVDPEGNESIWYNGKVVGNTTSGSYSYSIQKSLAFA 816 +A + KG R V L T G G +G TSG + S +A Sbjct: 295 AKAFLESLQKGPSRCRVGLKPQTRQPIRAGAVLFDNEGNRIGVVTSGGFGPSFDGPVAMG 354 Query: 817 YVPVQLSEVGQQVEVELLGKNYPAVIIQEPLVLTE 851 YVPV G +V EL GK + P V Sbjct: 355 YVPVAWKVEGTEVFTELRGKKIALSVHSLPFVEQR 389 >3BHF-A nrPDB Length = 390 Score = 354 bits (907), Expect = 1e-97, Method: Composition-based stats. Identities = 81/394 (20%), Positives = 162/394 (41%), Gaps = 32/394 (8%) Query: 50 AETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHP---GINLK 106 + +++G G +G++ Y LAK G+K +L++ + + H H G Sbjct: 5 FDVIVVGAGSMGMAAGYQLAKQGVK-TLLVDAFDPPHTNGSHHGDTKIIRHAYGEGREYV 63 Query: 107 KIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQ-MTRTGWHATEQYLIE 165 + S +L+ +LE+ET + F + G + P F + M H+ L+E Sbjct: 64 PLALRSQELWYELEKETHHKI-FTKTGVLVFG--PKGESAFVAETMEAAKEHSLTVDLLE 120 Query: 166 PEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKAR 225 ++I + +P + + + ++ P G + + A A GA + V Sbjct: 121 GDEINKRWPGITVPENYNAIFEPNSGVLFSENCIRAYRELAEARGAKVLTHTRVEDFDIS 180 Query: 226 SDGTWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYVVTSTISEVKALK 285 D + +ET GS A++++ + G W ++ + L+ PL P ++ VV S Sbjct: 181 PD-SVKIETANGSYTADKLIVSMGAWNSKLLSKLNLDIPLQP--YRQVVGFFES------ 231 Query: 286 RELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNGVPPGFGKELFESDLDRI 345 E D++ ++ + +G+ +G + S ++ + T FG+++ ++R Sbjct: 232 DESKYSNDIDFPGFMVEVPNGIYYG-FPSFGGCGLKLGYHT------FGQKIDPDTINRE 284 Query: 346 M-------EHIKAAMEMVPVLKKADIINVVNGPITYSPDILPMVGPHQGVRNYWVAIGF- 397 +++A +E ++ T + D ++ H N +A GF Sbjct: 285 FGVYPEDESNLRAFLEEYMPGANGELKRGAVCMYTKTLDEHFIIDLHPEHSNVVIAAGFS 344 Query: 398 GYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNR 431 G+G + GVG+ LS L G+ D+ NR Sbjct: 345 GHGFKFSSGVGEVLSQLALTGKTEHDISIFSINR 378 >1WSR-A nrPDB Length = 375 Score = 352 bits (903), Expect = 3e-97, Method: Composition-based stats. Identities = 100/393 (25%), Positives = 169/393 (43%), Gaps = 40/393 (10%) Query: 469 QRVSGLYQRLESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFEPVGSEYKQVMQR 528 +R L M AGW P QYR S + + Q Sbjct: 6 RRTPLYDFHLAHGGKMVAFAGWSLP---------VQYRDSHTDS---------HLHTRQH 47 Query: 529 VAVTDLSPFGKFNIKGQDSIRLLDHLFANVI--PKVGFTNISHMLTPKGRVYAELTVSHQ 586 ++ D+S + I G D ++L++ L I + +S G + +L V++ Sbjct: 48 CSLFDVSHMLQTKILGSDRVKLMESLVVGDIAELRPNQGTLSLFTNEAGGILDDLIVTNT 107 Query: 587 SPGEFLLITGSGSELHDLRWIEE---EAVKGGYDVEIKNITDELGVLGVAGPQARKVLQK 643 S G +++ +G DL +++ E G DV ++ + + +L + GP A +VLQ Sbjct: 108 SEGHLYVVSNAGCWEKDLALMQDKVRELQNQGRDVGLEVLDN--ALLALQGPTAAQVLQA 165 Query: 644 LTSEDLSDDVFKFLQTKSLKVSNIP-VTAIRISYTGELGWELYHRREDSVALYDAIMNAG 702 ++DL F+ + ++V + R YTGE G E+ +V L AI+ Sbjct: 166 GVADDLRK--LPFMTSAVMEVFGVSGCRVTRCGYTGEDGVEISVPVAGAVHLATAILKNP 223 Query: 703 QEEGIDNFGTYAMNALRLEKAFRAWGLEMNCDTNPLEAGLEYFVKLNKPA--DFIGKQAL 760 + + G A ++LRLE +G +++ T P+E L + + + A DF G + + Sbjct: 224 E---VKLAGLAARDSLRLEAGLCLYGNDIDEHTTPVEGSLSWTLGKRRRAAMDFPGAKVI 280 Query: 761 -KQIKAKGLKRR--LVCLTLATDDVDPEGNESIWYNGKVVGNTTSGSYSYSIQKSLAFAY 817 Q+K + +RR L+C P N G +G TSG S S++K++A Y Sbjct: 281 VPQLKGRVQRRRVGLMCEGAPMRAHSPILN----MEGTKIGTVTSGCPSPSLKKNVAMGY 336 Query: 818 VPVQLSEVGQQVEVELLGKNYPAVIIQEPLVLT 850 VP + S G + VE+ K AV+ + P V T Sbjct: 337 VPCEYSRPGTMLLVEVRRKQQMAVVSKMPFVPT 369 >2GAG-A nrPDB Length = 965 Score = 339 bits (870), Expect = 2e-93, Method: Composition-based stats. Identities = 100/401 (24%), Positives = 184/401 (45%), Gaps = 29/401 (7%) Query: 470 RVSGLYQ-RLESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFEPVGSEYKQVMQR 528 R++ ++ L W++P W+Y +T + +R E K V Sbjct: 575 RITAMHSWHLSHGAEFEDVGQWKRP-WYYPQAGETMDQAVYR----------ESKAVRDS 623 Query: 529 VAVTDLSPFGKFNIKGQDSIRLLDHLFAN--VIPKVGFTNISHMLTPKGRVYAELTVSHQ 586 V + D + GK I+G+D+ L+ ++ N KVG M G ++ + Sbjct: 624 VGMLDATTLGKIEIRGKDAAEFLNRIYTNGYTKLKVGMGRYGVMCKADGMIFDDGVTLRL 683 Query: 587 SPGEFLLITGSGSELHDLRWIEE--EAVKGGYDVEIKNITDELGVLGVAGPQARKVLQKL 644 + FLL T +G L W+EE + DV ++T++L + V GP++R V+ KL Sbjct: 684 AEDRFLLHTTTGGAADVLDWLEEWLQTEWPDLDVTCTSVTEQLATVAVVGPRSRDVIAKL 743 Query: 645 TSE-DLSDDVFKFLQTKSLKV-SNIPVTAIRISYTGELGWELYHRREDSVALYDAIMNAG 702 S D+S++ FKF+ K + + S I RIS++GEL +E+ + +++ + AG Sbjct: 744 ASTVDVSNEGFKFMAFKDVVLDSGIEARISRISFSGELAFEIAVPAWHGLRVWEDVYAAG 803 Query: 703 QEEGIDNFGTYAMNALRLEKAFRAWGLEMNCDTNPLEAGLEYFVKLNKPADFIGKQALKQ 762 +E I +GT M+ LR EK F G + + P +AG+E+ V +K DFIG ++ + Sbjct: 804 EEFNITPYGTETMHVLRAEKGFIIVGQDTDGTVTPQDAGMEWVV--SKLKDFIGNRSYSR 861 Query: 763 I-KAKGLKRRLVCLTLATDDV-DPEGNESIWYNG-------KVVGNTTSGSYSYSIQKSL 813 A+ +++LV + + PEG + + + G TS S ++ ++ Sbjct: 862 ADNAREDRKQLVSVLPVDKSLRLPEGAALVASDALASEGITPMEGWVTSSYDSPNLGRTF 921 Query: 814 AFAYVPVQLSEVGQQVEVELLGKNYPAVIIQEPLVLTEPTR 854 A + + +G+ ++ + + V+ + L E +R Sbjct: 922 GLALIKNGRNRIGEVLKTPVGDQLVDVVVSETVLYDPEGSR 962 >3A8J-A nrPDB Length = 364 Score = 339 bits (869), Expect = 3e-93, Method: Composition-based stats. Identities = 90/392 (22%), Positives = 156/392 (39%), Gaps = 49/392 (12%) Query: 469 QRVSGLYQRLESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFEPVGSEYKQVMQR 528 Q+ Q M GW P + E+ V Sbjct: 3 QQTPLYEQHTLCGARMVDFHGWMMPLHY-------------------GSQIDEHHAVRTD 43 Query: 529 VAVTDLSPFGKFNIKGQDSIRLLDHLFANVIPKV---GFTNISHMLTPKGRVYAELTVSH 585 + D+S +++G + L +L AN + K+ G S ML G V +L V + Sbjct: 44 AGMFDVSHMTIVDLRGSRTREFLRYLLANDVAKLTKSGKALYSGMLNASGGVIDDLIVYY 103 Query: 586 QSPGEFLLITGSGSELHDLRWIEEEAVKGGYDVEIKNITDELGVLGVAGPQARKVLQKLT 645 + F L+ S + DL WI + A G ++ ++ D+L ++ V GP A+ L Sbjct: 104 FTEDFFRLVVNSATREKDLSWITQHAEPFGIEITVR---DDLSMIAVQGPNAQAKAATLF 160 Query: 646 SEDLSD-----DVFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHRREDSVALYDAIMN 700 ++ F +Q L ++ YTGE G+E+ E + + A++ Sbjct: 161 NDAQRQAVEGMKPFFGVQAGDLFIAT-------TGYTGEAGYEIALPNEKAADFWRALVE 213 Query: 701 AGQEEGIDNFGTYAMNALRLEKAFRAWGLEMNCDTNPLEAGLEYFVKLN-KPADFIGKQA 759 AG + G A + LRLE +G EM+ +PL A + + + DFIG++A Sbjct: 214 AG----VKPCGLGARDTLRLEAGMNLYGQEMDETISPLAANMGWTIAWEPADRDFIGREA 269 Query: 760 LKQIKAKGLKRRLVCLTLATDDVDPEGNESIW---YNGKVVGNTTSGSYSYSIQKSLAFA 816 L+ + G + +LV L + V + + G TSG++S ++ S+A A Sbjct: 270 LEVQREHGTE-KLVGLVMTEKGVLRNELPVRFTDAQGNQHEGIITSGTFSPTLGYSIALA 328 Query: 817 YVPVQLSEVGQQVEVELLGKNYPAVIIQEPLV 848 VP +G+ V++ + P + + V Sbjct: 329 RVP---EGIGETAIVQIRNREMPVKVTKPVFV 357 >1VRQ-A nrPDB Length = 964 Score = 334 bits (856), Expect = 1e-91, Method: Composition-based stats. Identities = 95/393 (24%), Positives = 174/393 (44%), Gaps = 28/393 (7%) Query: 477 RLESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFEPVGSEYKQVMQRVAVTDLSP 536 L W++P W+Y ++ +R E K V V + D S Sbjct: 582 HLAHGAKFEDVGQWKRP-WYYPQDGESMDEAVYR----------ECKAVRDSVGMLDAST 630 Query: 537 FGKFNIKGQDSIRLLDHLFAN--VIPKVGFTNISHMLTPKGRVYAELTVSHQSPGEFLLI 594 GK I+G+D+ L+ ++ N KVG M G ++ + + FL+ Sbjct: 631 LGKIEIRGKDAAEFLNRMYTNGYTKLKVGMGRYGVMCKADGMIFDDGVTLRLAEDRFLMH 690 Query: 595 TGSGSELHDLRWIEE--EAVKGGYDVEIKNITDELGVLGVAGPQARKVLQKLTSE-DLSD 651 T +G L W+EE + DV ++T++L + V GP++R V+ KL S D+S+ Sbjct: 691 TTTGGAADVLDWLEEWLQTEWPELDVTCTSVTEQLATVAVVGPRSRDVIAKLASSLDVSN 750 Query: 652 DVFKFLQTKSLKV-SNIPVTAIRISYTGELGWELYHRREDSVALYDAIMNAGQEEGIDNF 710 D FKF+ + + + S I RIS++GEL +E+ + +++ + AGQE I + Sbjct: 751 DAFKFMAFQDVTLDSGIEARISRISFSGELAFEIAIPAWHGLQVWEDVYAAGQEFNITPY 810 Query: 711 GTYAMNALRLEKAFRAWGLEMNCDTNPLEAGLEYFVKLNKPADFIGKQALKQI-KAKGLK 769 GT M+ LR EK F G + + P +AG+E+ V +K DF+GK++ + + + Sbjct: 811 GTETMHVLRAEKGFIIVGQDTDGTVTPQDAGMEWVV--SKLKDFVGKRSFSREDNVREDR 868 Query: 770 RRLVCLTLAT------DDVDPEGNESIWYNG--KVVGNTTSGSYSYSIQKSLAFAYVPVQ 821 + LV + + +++ G + G T S ++ ++ A + Sbjct: 869 KHLVSVLPVDSSLRLAEGAALVAADAVASEGVTPMEGWVTHAYNSPALGRTFGLALIKNG 928 Query: 822 LSEVGQQVEVELLGKNYPAVIIQEPLVLTEPTR 854 + +G+ ++ + G+ + L E +R Sbjct: 929 RNRIGEVLKTPVDGQLVDVQVSDLVLFDPEGSR 961 >1ZOV-A nrPDB Length = 386 Score = 329 bits (842), Expect = 5e-90, Method: Composition-based stats. Identities = 75/394 (19%), Positives = 157/394 (39%), Gaps = 32/394 (8%) Query: 50 AETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHP---GINLK 106 + +++G G +G++ Y+LAK G+K +L++ + + H H G Sbjct: 4 FDVIVVGAGSMGMAAGYYLAKQGVK-TLLVDSFDPPHTNGSHHGDTRIIRHAYGEGREYV 62 Query: 107 KIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQ-MTRTGWHATEQYLIE 165 + +L+ +LE+ET + F Q G + P F + M H+ E L E Sbjct: 63 PFALRAQELWYELEKETHHKI-FTQTGVLVYG--PKGGSAFVSETMEAANIHSLEHELFE 119 Query: 166 PEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKAR 225 +++ + + + + ++ P G + + A A GA + PV + Sbjct: 120 GKQLTDRWAGVEVPDNYEAIFEPNSGVLFSENCIQAYRELAEAHGATVLTYTPVEDFEVT 179 Query: 226 SDGTWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYVVTSTISEVKALK 285 D ++T +GS AN++V + G W ++ + +E PL P ++ VV Sbjct: 180 ED-LVTIKTAKGSYTANKLVVSMGAWNSKLLSKLDVEIPLQP--YRQVVGFFEC------ 230 Query: 286 RELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNGVPPGFGKELFESDLDRI 345 E + ++ + +G+ +G + S ++ + + +G+++ ++R Sbjct: 231 DEAKYSNNAHYPAFMVEVENGIYYG-FPSFGGSGLKIGYHS------YGQQIDPDTINRE 283 Query: 346 M-------EHIKAAMEMVPVLKKADIINVVNGPITYSPDILPMVGPHQGVRNYWVAIGF- 397 +++ +E ++ T +PD ++ H N +A GF Sbjct: 284 FGAYPEDEANLRKFLEQYMPGANGELKKGAVCMYTKTPDEHFVIDLHPKYSNVAIAAGFS 343 Query: 398 GYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNR 431 G+G + VG+ L+ G+ D+ NR Sbjct: 344 GHGFKFSSVVGETLAQLATTGKTEHDISIFSLNR 377 >3TFJ-A nrPDB Length = 369 Score = 328 bits (840), Expect = 8e-90, Method: Composition-based stats. Identities = 66/339 (19%), Positives = 149/339 (43%), Gaps = 15/339 (4%) Query: 515 FEPVGSEYKQVMQRVAVTDLSPFGKFNIKGQDSIRLLDHLFANVIPK--VGFTNISHMLT 572 F + YK + + V + D++ + I G+DS L+ + + K +G ++ Sbjct: 41 FGSIEDSYKHLKEHVQIWDVAAERQVEISGKDSAELVQLMTCRDLSKSKIGRCYYCPIID 100 Query: 573 PKGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEEAVKGGYDVEIKNITDELGVLGV 632 G + + V ++ + + + + G+ ++K + + ++ + Sbjct: 101 ENGNLVNDPVVLKLDENKWWISIADSDVIFFAK-----GLASGHKFDVKIVEPVVDIMAI 155 Query: 633 AGPQARKVLQKLTSEDLSDDVFKFLQTKSLKVSNIPVTAIRISYTGELGWELYH-RREDS 691 GP++ +++K+ + +++ KF R ++ + G+E+Y + Sbjct: 156 QGPKSFALMEKVFGKKITE--LKFFGFDYFDFEGTKHLIARSGWSKQGGYEVYVENTQSG 213 Query: 692 VALYDAIMNAGQEEGIDNFGTYAMNAL-RLEKAFRAWGLEMNCDTNPLEAGLEYFVKLNK 750 LYD + G+E + G N + R+E A ++G + + + NP E G + +V L+ Sbjct: 214 QKLYDHLFEVGKEFNV---GPGCPNLIERIESALLSYGNDFDNNDNPFECGFDQYVSLDS 270 Query: 751 PADFIGKQALKQIKAKGLKRRLVCLTLATDDVDPEGNESIW-YNGKVVGNTTSGSYSYSI 809 +F+GK+ LK+IK KG +++L + + ++ G+++I+ N V+G S YS Sbjct: 271 DINFLGKEKLKEIKLKGPQKKLRGVKIDIKEISLTGSKNIYDENNNVIGELRSACYSPHF 330 Query: 810 QKSLAFAYVPVQLSEVGQQVEVELLGKNYPAVIIQEPLV 848 QK + A + E Q ++++ + P + Sbjct: 331 QKVIGIAMIKKSHWEASQGFKIQINDNTINGNVCDLPFI 369 >1NG3-A nrPDB Length = 390 Score = 304 bits (779), Expect = 1e-82, Method: Composition-based stats. Identities = 89/382 (23%), Positives = 153/382 (40%), Gaps = 51/382 (13%) Query: 66 YHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYD----SIKLYEKLEE 121 Y+LAK K+ L E + +T AAG+ H + +D S +LY+ L E Sbjct: 42 YYLAKEN-KNTALFESGTMGGRTTSAAAGMLGA-HAECEERDAFFDFAMHSQRLYKGLGE 99 Query: 122 ETGQVVGF----HQPGSIRLATTPVRVDEFKY--QMTRTGWHATEQYL-IEPEKIQEMFP 174 E + G H G +LA + V + + + W++ E+ L EP ++F Sbjct: 100 ELYALSGVDIRQHNGGMFKLAFSEEDVLQLRQMDDLDSVSWYSKEEVLEKEPYASGDIF- 158 Query: 175 LLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARSDGTWDVET 234 + D H++PY + A A+ GA + PV ++ + + ++T Sbjct: 159 --------GASFIQDDVHVEPYFVCKAYVKAAKMLGAEIFEHTPVLHVERDGEALF-IKT 209 Query: 235 PQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYVVTSTISEVKALKRELPVLRDL 294 P G + AN +V A+G W+ K +GL + +PV+ + + ++P+ + L Sbjct: 210 PSGDVWANHVVVASGVWSGMFFKQLGLNNAFLPVKGEC--------LSVWNDDIPLTKTL 261 Query: 295 EGSY-YLRQERDGLLFGPYESQEKMKVQDSWVTNGVPPGFGKELFESDLDRIMEHIKAAM 353 + Y+ + G L V + PG E DL + +K A Sbjct: 262 YHDHCYIVPRKSGRLV---------------VGATMKPGDWSE--TPDLGGLESVMKKAK 304 Query: 354 EMVPVLKKADIINVVNGPITYSPDILPMVGPHQG-VRNYWVAIGFGYGIIHAGGVGKYLS 412 M+P ++ + G + D P +G H R + A F GI+ A G +S Sbjct: 305 TMLPPIQNMKVDRFWAGLRPGTKDGKPYIGRHPEDSRILFAAGHFRNGILLAPATGALIS 364 Query: 413 DWILHGEPPFD-LIELDPNRYG 433 D I++ E D L +R Sbjct: 365 DLIMNKEVNQDWLHAFRIDRKE 386 >3SM8-A nrPDB Length = 381 Score = 264 bits (675), Expect = 1e-70, Method: Composition-based stats. Identities = 84/389 (21%), Positives = 145/389 (37%), Gaps = 44/389 (11%) Query: 50 AETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIH 109 A+ ++IG G G S Y L+ G + VVL +++ ST +A T + ++ + Sbjct: 10 ADYLVIGAGIAGASTGYWLSAHG-RVVVLEREAQPGYHSTGRSAAHYTVAYGTPQVRALT 68 Query: 110 YDSIKLYEK----------LEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHAT 159 S ++ L VV F +E + Q Sbjct: 69 AASRAFFDNPPAGFCEHPLLSPRPEMVVDFSD-----------DPEELRRQYESGKALVP 117 Query: 160 EQYLIEPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPV 219 + L++ E+ + P+L +KV Y+P ID +L G R+ + Sbjct: 118 QMRLLDAEQACSIVPVLRRDKVFGATYDPTGADIDTDALHQGYLRGIRRNQGQVLCNHEA 177 Query: 220 TSLKARSDGTWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEH-PLIPVQHQYVVTSTI 278 ++ R DG W+V GS RA +VNAAG W + + G+ L P + + + Sbjct: 178 LEIR-RVDGAWEVRCDAGSYRAAVLVNAAGAWCDAIAGLAGVRPLGLQPKRRSAFIFAPP 236 Query: 279 SEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNGVPPGFGKELF 338 + + P+L L+ S+YL+ + G+L G + + ++ D + Sbjct: 237 PGIDC--HDWPMLVSLDESFYLKPDA-GMLLGSPANADPVEAHD--------------VQ 279 Query: 339 ESDLDRIMEHIKAAMEMVPVLKKADIINVVNGPITYSPDILPMVGPHQGVRN-YWVAIGF 397 LD +E L + G ++ D + G +WVA Sbjct: 280 PEQLDIATGMY--LIEEATTLTIRRPEHTWAGLRSFVADGDLVAGYAANAEGFFWVAAQG 337 Query: 398 GYGIIHAGGVGKYLSDWILHGEPPFDLIE 426 GYGI + +G+ + I H P L E Sbjct: 338 GYGIQTSAAMGEASAALIRHQPLPAHLRE 366 >4YSH-A nrPDB Length = 376 Score = 256 bits (653), Expect = 4e-68, Method: Composition-based stats. Identities = 104/397 (26%), Positives = 175/397 (44%), Gaps = 44/397 (11%) Query: 49 RAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTT---YFHPGINL 105 R + I+GGG +G ++ + LAK + V + EK + +G++ AAG+ F L Sbjct: 4 RYDVAIVGGGVIGAAIGFELAKRRHR-VAIFEKGTMGSGASSAAAGMLGAQSEFSTSSPL 62 Query: 106 KKIHYDSIKL----YEKLEEETGQVVGFHQPGSIRLATTPVRVDE-FKYQMTRTGWHATE 160 + S L E+L E TG +G + G I+LATT D+ +++ G Sbjct: 63 VPLALQSRALMPALAEELRERTGIDIGLVEKGLIKLATTEEEADDLYRHYTFWRGIGEPV 122 Query: 161 QYLIEPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVT 220 Q+L + E + EM P L + +Y PGDG + L ALA A GA L V Sbjct: 123 QWLTKGEAL-EMEPRL-AEALAGAMYIPGDGQVSAPDLAAALAYAAASAGACLYEYTEVF 180 Query: 221 SLKARSDGTWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYVVTSTISE 280 +++ S G ++T G+ A +V A+G WA +G +GL + PV+ + V+ Sbjct: 181 DIRSDSSGHV-LDTTGGTFAAEAVVIASGAWAARLGARVGLSLSVYPVKGECVM------ 233 Query: 281 VKALKRELPVLRDL----EGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNGVPPGFGKE 336 ++ +P+L+ G Y + + + LL G P F + Sbjct: 234 ---VRAPVPLLQTTVFAKNGCYIVPKSGNRLLIG---------------ATSTPGTFDRR 275 Query: 337 LFESDLDRIMEHIKAAMEMVPVLKKADIINVVNGPITYSPDILPMVGPHQGVRNYWVAIG 396 + +M + A +VP +++A+ + +G + D LP +G H R +VA G Sbjct: 276 VSAGG---VMNLLHRAAHLVPDIEQAEWVASWSGIRPQTEDGLPYLGEHPERRGLFVAAG 332 Query: 397 -FGYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRY 432 + GI+ + G ++D + E FDL R+ Sbjct: 333 HYRNGILLSPLTGLLVADLVERKETAFDLAPFSLTRH 369 >2UZZ-A nrPDB Length = 372 Score = 171 bits (433), Expect = 1e-42, Method: Composition-based stats. Identities = 72/393 (18%), Positives = 136/393 (34%), Gaps = 30/393 (7%) Query: 49 RAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHP---GINL 105 + + +IIG G VG + Y+ +AG+ +V++ + H H G Sbjct: 2 KYDLIIIGSGSVGAAAGYYATRAGL-NVLMTDAHMPPHQHGSHHGDTRLIRHAYGEGEKY 60 Query: 106 KKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLIE 165 + + L+++L F + G I L P ++ Sbjct: 61 VPLVLRAQMLWDELSRHNEDDPIFVRSGVINLG--PADSTFLANVAHSAEQWQLNVEKLD 118 Query: 166 PEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKAR 225 + I +P + + GL+ G + A++ G + PVT+++ Sbjct: 119 AQGIMARWPEIRVPDNYIGLFETDSGFLRSELAIKTWIQLAKEAGCAQLFNCPVTAIRHD 178 Query: 226 SDGTWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYVVTSTISEVKALK 285 DG +ET G +A + + AG W +++ E P+ PV+ + ++K Sbjct: 179 DDGVT-IETADGEYQAKKAIVCAGTWVKDLLP----ELPVQPVR-KVFAWYQADGRYSVK 232 Query: 286 RELPV----LRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNGVPPGFGKELFESD 341 + P L + + Y E D L G + + + D V G E F Sbjct: 233 NKFPAFTGELPNGDQYYGFPAENDALKIGKHNGGQVIHSADERVPFAEVVSDGSEAFP-- 290 Query: 342 LDRIMEHIKAAMEMVPVLKKADIINVVNGPITYSPDILPMVGPHQGVRNYWVAIGF-GYG 400 ++P + + SPD ++ G N + G G+G Sbjct: 291 ---------FLRNVLPGI--GCCLYGAACTYDNSPDEDFIIDTLPGHDNTLLITGLSGHG 339 Query: 401 IIHAGGVGKYLSDWILHGEPPFDLIELDPNRYG 433 A +G+ +D+ + FDL +R+ Sbjct: 340 FKFASVLGEIAADFAQDKKSDFDLTPFRLSRFQ 372 >5X1I-A nrPDB Length = 474 Score = 109 bits (273), Expect = 4e-24, Method: Composition-based stats. Identities = 80/394 (20%), Positives = 142/394 (36%), Gaps = 87/394 (22%) Query: 515 FEPVGSEYKQVMQRVAVTDLSP-FGKFNIKGQDSIRLLDHLFANVIP--KVGFTNISHML 571 F +E + D + I+G+D+++LL N + + Sbjct: 41 FSNWRTEQWAWRNSAVLFDQTHHMVDLYIRGKDALKLLSDTMINSPKGWEPNKAKQYVPV 100 Query: 572 TPKGRVYAELTVSHQSPGEFLLITGSGSELHDLRWIEEEAVKGGYDVEI--KNITDELGV 629 TP G V + + + + EF+ + W+ A GGY+V+I + + + Sbjct: 101 TPYGHVIGDGIIFYLAEEEFVYV----GRAPAANWLMYHAQTGGYNVDIVHDDRSPSRPM 156 Query: 630 ----------LGVAGPQARKVLQKLTSEDLSDDVFKFLQTKSLKVSNIPVTAIRISYTGE 679 + GP+A V++KL L + KF + ++ + + +R G Sbjct: 157 GKPVQRISWRFQIQGPKAWDVIEKLHGGTL--EKLKFFNMAEMNIAGMKIRTLRHGMAGA 214 Query: 680 LGWELYHRREDSVALYDAIMNAGQEEGIDNFGTYAMNALRLEKA---------------- 723 G E++ E +AI+ AG+E G+ G+ A + LE Sbjct: 215 PGLEIWGPYETQEKARNAILEAGKEFGLIPVGSRAYPSNTLESGWIPSPLPAIYTGDKLK 274 Query: 724 -FRAW-------------GLEMNCDT-----NPLEAGLEYFVKLNKPADFIGKQALKQIK 764 +R W G ++ + NP E G FVK + DFIG+ AL+ I Sbjct: 275 AYREWLPANSYEASGAIGGSFVSSNIEDYYVNPYEIGYGPFVKFDH--DFIGRDALEAI- 331 Query: 765 AKGLKRRLVCLTLATDDVDPEGNESIWYN---------------------------GKVV 797 +R+ V L DD+ G VV Sbjct: 332 DPATQRKKVTLAWNGDDMAKIYASLFDTEADAHYKFFDLPLANYANTNADAVLDAAGNVV 391 Query: 798 GNTTSGSYSYSIQKSLAFAYVPVQLSEVGQQVEV 831 G + YSY+ +++L+ A + ++ VG ++ V Sbjct: 392 GMSMFTGYSYNEKRALSLATIDHEIP-VGTELTV 424 >5XAO-A nrPDB Length = 445 Score = 95.3 bits (235), Expect = 1e-19, Method: Composition-based stats. Identities = 66/376 (17%), Positives = 141/376 (37%), Gaps = 33/376 (8%) Query: 65 AYHLAKAGMK--DVVLLEKSELTAGSTWHAAGLTTYFHPGINLK-----KIHYDSIKLYE 117 A HL ++G +V +L+ + + +AG G++L+ ++ ++ +++ Sbjct: 24 ALHLVRSGYTPSNVTVLDAYPIP---SSQSAGNDLAKIMGVSLRNPVDLQLALEARQMWN 80 Query: 118 KLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTR---TGWHATEQYLIEPEKIQEMFP 174 E+ FH G + A + + K G AT ++L ++I + P Sbjct: 81 ---EDELFKKFFHNTGRLDCAHGEKDIADLKSGYQALVDAGLDATNEWLDSEDEILKRMP 137 Query: 175 LLNMNKVLA--GLYNPGDGHIDPYSLTMALAAGARKCGALL-KYPAPVTSLKARSDGT-W 230 LL+ +++ +++ G + A+ R G Y A ++G Sbjct: 138 LLSRDQIKGWKAIFSKDGGWLAAAKAINAVGEYLRDQGVRFGFYGAGSFKAPLLAEGVCI 197 Query: 231 DVETPQGS-MRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYVVTSTISEVKALKRELP 289 VET G+ A+++V AAG W+ + + L + Y E A + P Sbjct: 198 GVETVDGTRYYADKVVLAAGAWSPTLVE---LHEQCVSKAWVYGHIQLTPEEAARYKNSP 254 Query: 290 VLRDLEGSYYLRQERDGL--LFGPYESQEKMKVQDSWVTN-----GVPPGFGKELFESDL 342 V+ + + ++ G+ + + + K+ + VP K ++ Sbjct: 255 VVYNGDVGFFFEPNEHGVIKVCDEFPGFTRFKMHQPFGAKAPKRISVPRSHAKHPTDTIP 314 Query: 343 DRIMEHIKAAMEMVPV-LKKADIINVVNGPITYSPDILPMVGPHQGVRNYWVAIG-FGYG 400 D I+ A+ K + N T + D ++ H +N+ +A G G+ Sbjct: 315 DASDVSIRRAIATFMPQFKNKKMFNQAMCWCTDTADAALLICEHPEWKNFVLATGDSGHS 374 Query: 401 IIHAGGVGKYLSDWIL 416 +GK++ + + Sbjct: 375 FKLLPNIGKHVVELLE 390 >3VQR-A nrPDB Length = 447 Score = 80.2 bits (196), Expect = 4e-15, Method: Composition-based stats. Identities = 64/403 (15%), Positives = 138/403 (34%), Gaps = 36/403 (8%) Query: 49 RAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSE-LTAGSTWHAAGLTTYFHPGINLKK 107 R + V++G G VG++ AY+L V++++ +G + + F + Sbjct: 23 RFDYVVVGAGVVGLAAAYYLKVWSGGSVLVVDAGHAPGSGDSGRSMAAFRTFFSSTMNRL 82 Query: 108 IHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLIEPE 167 + +++L+E + G+ +G + G + + R E + + G + +I PE Sbjct: 83 VAGSTVRLFED-AQRGGEDLGLVKSGYLFV-YDRERWREVEEPLREAGEEGRDYLIIPPE 140 Query: 168 KI------------QEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKY 215 ++ E +L + V + G +D + A G + Sbjct: 141 ELERRLGMNTRVSDGEEAEVLGVGDVEGAVLIRSAGFLDAEKVVDYYYRRASGAGVEFIF 200 Query: 216 PAPVTSLKARSDGTWDVE---------------TPQGSM--RANRIVNAAGFWAREVGKM 258 V ++ + +E G+ ++V AAG W+ + Sbjct: 201 GRRVVGVELKPRVELGIEGEPLPWQEARASAAVLSDGTRVEVGEKLVVAAGVWSNRLLNP 260 Query: 259 IGLEHPLIPVQHQYV-VTSTISEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEK 317 +G++ P + V+++ ++ + RE + + + +L P + Sbjct: 261 LGIDTFSRPKKRMVFRVSASTEGLRRIMREGDLAGAGAPPLIILPK--RVLVRPAPREGS 318 Query: 318 MKVQDSWVTNGVPPGFGKELFESDLDRIMEHIKAAMEMVPVLKKADIINVVNGPITYSPD 377 VQ S G P ++ + + + +P + A G S D Sbjct: 319 FWVQLS-DNLGRPFALEEDPQPEEHYYSLAILPILSLYLPQFQDAYPSGGWAGHYDISFD 377 Query: 378 ILPMVGPHQGVRNYWVAIGFGYGIIHAGGVGKYLSDWILHGEP 420 P+V A G GI+ + +G+ + L E Sbjct: 378 ANPVVFEPWESGIVVAAGTSGSGIMKSDSIGRVAAAVALGMES 420 >3PS9-A nrPDB Length = 676 Score = 59.4 bits (142), Expect = 7e-09, Method: Composition-based stats. Identities = 72/451 (15%), Positives = 138/451 (30%), Gaps = 74/451 (16%) Query: 24 GRPRSVCGREGEEKPPLSAETQWKDRA-----ETVIIGGGCVGVSLAYHLAKAGMKDVV- 77 GR R + E+ PL W +R E IIGGG L+ L + G + + Sbjct: 242 GRKREMLCGVMEQTLPLPCSAPWFNRTGSSKREAAIIGGGIASALLSLALLRRGWQVTLY 301 Query: 78 LLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYD-----SIKLYEKLEEETGQVVGFHQP 132 +++ S L + + + Y++L + Sbjct: 302 CADEAPALGASGNRQGALYPLLSKHDEALNRFFSNAFTFARRFYDQLPVKFDHDWC---- 357 Query: 133 GSIRLATTPVRVDEFKYQMTRTGWHATEQYLIEPEKIQEMFPLLNMNKVLAGLYNPGDGH 192 G +L ++++ + L + + + + +G+ P G Sbjct: 358 GVTQLGWDEK----SQHKIAQMLSMDLPAELAVAVEANAVEQITGVATNCSGITYPQGGW 413 Query: 193 IDPYSLTMALAAGARKCGALLKYPAPVTSLKARSDGTWDVETPQGSMRANRIVNAAGFWA 252 + P LT + A++ G + Y + + +R D W + + +V A Sbjct: 414 LCPAELTRNVLELAQQQGLQIYYQYQLQNF-SRKDDCWLLNFAGDQQATHSVVVLANGHQ 472 Query: 253 REVGKMIGLEHPLIPVQHQYVVTSTISEVKALKRELPVLRDLEGSYYLRQERDGLLFGPY 312 P+ V Q T E+ LK+ L DG L Sbjct: 473 ISRFSQTS-TLPVYSVAGQVSHIPTTPELAELKQVLCY--------------DGYLTPQN 517 Query: 313 ESQEKMKVQDSWVTNGVPPGFGKELFESDLDRIMEHIKAAMEMVPVLKKADIINVVN--- 369 + + + S+ + + D ++ + ++ P + A ++V + Sbjct: 518 PANQHHCIGASYHRGSEDTAYSE-------DDQQQNRQRLIDCFPQAQWAKEVDVSDKEA 570 Query: 370 --GPITYSPDILPMVGPHQGV-----------------------RNYWVAIGFGY-GIIH 403 G + D LPMVG + ++ G G+ Sbjct: 571 RCGVRCATRDHLPMVGNVPDYEATLVEYASLAEQKDEAVSAPVFDDLFMFAALGSRGLCS 630 Query: 404 AGGVGKYLSDWILHGEPPFD---LIELDPNR 431 A + L+ + P D L L+PNR Sbjct: 631 APLCAEILAAQMSDEPIPMDASTLAALNPNR 661 >3PVC-A nrPDB Length = 689 Score = 57.1 bits (136), Expect = 4e-08, Method: Composition-based stats. Identities = 83/440 (18%), Positives = 139/440 (31%), Gaps = 73/440 (16%) Query: 39 PLSAETQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAG-STWHAAGLTT 97 P + IIGGG V A L + G + ++ G S L Sbjct: 254 PWYHRPAATRCDDIAIIGGGIVSALTALALQRRGAVVTLYCADAQPAQGASGNRQGALYP 313 Query: 98 YFHPGINLKKIHYDS-----IKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMT 152 + + + + S + Y++L E+ G G +LA +M Sbjct: 314 LLNGKNDALETFFTSAFTFARRQYDQLLEQ-GIAFDHQWCGVSQLAFDDKS-RGKIEKML 371 Query: 153 RTGWHATEQYLIEPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGAL 212 T W + E++ E L ++ G++ P G + P LT AL A++ G Sbjct: 372 HTQWPVEFAEAMSREQLSE---LAGLDCAHDGIHYPAGGWLCPSDLTHALMMLAQQNGMT 428 Query: 213 LKYPAPVTSLKARSDGTWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQY 272 Y + LK R D W + T S A A + G P H Sbjct: 429 CHYQHELQRLK-RIDSQWQL-TFGQSQAAKH-------HATVILA-TGHRLPEWEQTHHL 478 Query: 273 VVTSTISEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNGVPPG 332 +++ + + PVL L+ DG L + + + S+ + Sbjct: 479 PLSA-VRGQVSHIPTTPVLSQLQQVLCY----DGYLTPVNPANQHHCIGASYQRGDIATD 533 Query: 333 FGKELFESDLDRIMEHIKAAMEMVPVL---KKADIINVVN--GPITYSPDILPMVGPHQG 387 F L E+ + + +P + ++ D+ + G D LPMVG Sbjct: 534 F-------RLTEQQENRERLLRCLPQVSWPQQVDVSDNQARCGVRCAIRDHLPMVGAVPD 586 Query: 388 VRN-------------------------------YWVAIGFGY-GIIHAGGVGKYLSDWI 415 ++ G G G+ A V + L+ + Sbjct: 587 YAATLAQYQDLSRRIQHGGESEVNDIAVAPVWPELFMVGGLGSRGLCSAPLVAEILAAQM 646 Query: 416 LHGEPPFD---LIELDPNRY 432 P D L L+PNR+ Sbjct: 647 FGEPLPLDAKTLAALNPNRF 666 >5EZ7-A nrPDB Length = 392 Score = 55.2 bits (131), Expect = 1e-07, Method: Composition-based stats. Identities = 44/268 (16%), Positives = 79/268 (29%), Gaps = 40/268 (14%) Query: 49 RAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLK-- 106 + +I+GGG G+ L L +AG VL+E + L G + + G+ H G Sbjct: 7 STDILIVGGGIAGLWLNARLRRAGY-ATVLVESASLGGGQSVKSQGII---HGGAKYALH 62 Query: 107 -KIHYDSIKLYEKLEEET----GQVVGFHQPGSIRLAT-----TPVRVDEFKYQMTRTGW 156 + S + + + G G L+ +P + + Sbjct: 63 GALTGASEAIAD-MPRRWRACLGSDGELDLRGVRLLSEAHYLWSPGGLAGSLTSFFASKA 121 Query: 157 HATEQYLIEPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYP 216 + + E ++ P L Y + D L A G L Sbjct: 122 VRSRVEQAKGE---DLPPALRDKGFKGKAYRLTEIVFDVPDLI---RRLAELAGDSLLAG 175 Query: 217 APVTSLKARSDGTWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHP------------ 264 + L+ + +RA R+V +AG + + +GLE P Sbjct: 176 ERIEPLR-EGRELAGLCVDGREIRAQRVVLSAGAGNEALLRELGLEQPAMQRRPLHMVMV 234 Query: 265 ----LIPVQHQYVVTSTISEVKALKREL 288 L P+ + + Sbjct: 235 KAATLKPLYAHCLGAGPKPRITVTTHPT 262 >3DA1-A nrPDB Length = 561 Score = 51.0 bits (120), Expect = 2e-06, Method: Composition-based stats. Identities = 59/353 (16%), Positives = 124/353 (35%), Gaps = 53/353 (15%) Query: 47 KDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINL- 105 + + + ++IGGG G +A G++ L+E ++ +G++ + L H G+ Sbjct: 16 EKQLDLLVIGGGITGAGIALDAQVRGIQ-TGLVEMNDFASGTSSRSTKLV---HGGLRYL 71 Query: 106 --------KKIHYDSIKLYEKLE----EETGQVVGFHQPGSIRLATTPV-RVDEFKYQMT 152 ++ + +YE E + F + +T+ +V ++ + Sbjct: 72 KQFEIKLVAEVGKERAIVYENAPHVTTPEWMLLPIFKDGTFGKFSTSLGLKVYDYLADVR 131 Query: 153 RTGWHATEQYLIEPEKIQEMFPLLNMNKVL-AGLYNPGDGHIDPYSLTMALAAGARKCGA 211 + +Y++ ++ E PLL + G+Y + D LT+ + A GA Sbjct: 132 KDE----RRYMLNEKQTLEKEPLLRKENLKGGGIYV--EYRTDDARLTLEIMKEAVARGA 185 Query: 212 LLKYPAPVTSLKARSDGTWDV-------ETPQGSMRANRIVNAAGFWAREVGKMIGLEHP 264 + V S V +T ++ A ++VNAAG W + + +H Sbjct: 186 VALNYMKVESFIYDQGKVVGVVAKDRLTDTTH-TIYAKKVVNAAGPWVDTLREKDRSKH- 243 Query: 265 LIPVQHQYVVTSTISEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSW 324 +Y+ S + + P+ + + E DG + + K Sbjct: 244 -----GKYLKLSKGVHLVVDQSRFPLRQAVYFD----TESDGRMIFAIPREGK------T 288 Query: 325 VTNGVPPGFGKELFESDLDRIMEH--IKAAMEMVPVLK--KADIINVVNGPIT 373 + K++ + + AA M P L+ D+ + G Sbjct: 289 YIGTTDTFYDKDIASPRMTVEDRDYILAAANYMFPSLRLTADDVESSWAGLRP 341 >1QO8-A nrPDB Length = 566 Score = 50.6 bits (119), Expect = 3e-06, Method: Composition-based stats. Identities = 32/214 (14%), Positives = 70/214 (32%), Gaps = 26/214 (12%) Query: 46 WKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINL 105 + + +++G G G + + KAG +V+L++K+ + G++ +AG Sbjct: 118 PSETTQVLVVGAGSAGFNASLAAKKAGA-NVILVDKAPFSGGNSMISAGGMNAVGTKQQT 176 Query: 106 KKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTP-VRVDEFKYQMTRTGWHATEQYLI 164 D ++ + + + G Q I+L T + + + G + + Sbjct: 177 AHGVEDKVEWFIE-----DAMKGGRQQNDIKLVTILAEQSADGVQWLESLGANLDDLKRS 231 Query: 165 EPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKA 224 ++ + P G + L A++ G + + V L Sbjct: 232 GGARVDR-------------THRPHGGKSSGPEIIDTLRKAAKEQGIDTRLNSRVVKLVV 278 Query: 225 RSDGTWDVETPQGSMR------ANRIVNAAGFWA 252 D + G A +V A G + Sbjct: 279 NDDHSVVGAVVHGKHTGYYMIGAKSVVLATGGYG 312 >5KOX-A nrPDB Length = 476 Score = 49.4 bits (116), Expect = 7e-06, Method: Composition-based stats. Identities = 38/226 (16%), Positives = 71/226 (31%), Gaps = 54/226 (23%) Query: 51 ETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHY 110 + +I GGG G+ LA L G++ VVL ++ S + +H Sbjct: 6 DVIIAGGGPTGLMLAGELRLHGVRTVVLEKEPTPNQHS---------------RSRGLHA 50 Query: 111 DSIKLYEK--LEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLIEPEK 168 SI++ ++ L E + G + + L P+ Sbjct: 51 RSIEVMDQRGLLERFLAHGEQFRVGGFFAGLAAEWPADLDTAHSYV--------LAIPQV 102 Query: 169 IQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARSDG 228 + E L A + GA ++ V L +DG Sbjct: 103 VTER----------------------------LLTEHATELGAEIRRGCEVAGLDQDADG 134 Query: 229 TWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYVV 274 +RA +V G V +++G++ P P + + ++ Sbjct: 135 VTAELADGTRLRARYLVGCDGG-RSTVRRLLGVDFPGEPTRVETLL 179 >1D4E-A nrPDB Length = 572 Score = 47.5 bits (111), Expect = 2e-05, Method: Composition-based stats. Identities = 53/301 (17%), Positives = 99/301 (32%), Gaps = 27/301 (8%) Query: 47 KDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLK 106 K+ + VIIG G G++ A AG K V+LLEK + G+T AAG K Sbjct: 124 KETTDVVIIGSGGAGLAAAVSARDAGAK-VILLEKEPIPGGNTKLAAGGMNAAETKPQAK 182 Query: 107 KIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLIEP 166 +E++ ++ G + E + + + Sbjct: 183 ----------LGIEDKKQIMIDDTMKGGRNINDP-----ELVKVLANNSSDSIDWLTSMG 227 Query: 167 EKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARS 226 + ++ + + P G + L A K G ++ + V + + Sbjct: 228 ADMTDV--GRMGGASVNRSHRPTGGAGVGAHVAQVLWDNAVKRGTDIRLNSRVVRILEDA 285 Query: 227 DGTWDVETPQGSMR------ANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYVVTSTISE 280 G +G A+ +V AAG +A+ ++ + L + +T Sbjct: 286 SGKVTGVLVKGEYTGYYVIKADAVVIAAGGFAKNNERVSKYDPKLKGFKATNHPGATGDG 345 Query: 281 VKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNGVPPGFGKELFES 340 + + RDL+ Y++ G E ++ + V N F E+ Sbjct: 346 LDVALQAGAATRDLQ---YIQAHPTYSPAGGVMITEAVRGNGAIVVNREGNRFMNEITTR 402 Query: 341 D 341 D Sbjct: 403 D 403 >2RGO-A nrPDB Length = 607 Score = 47.1 bits (110), Expect = 3e-05, Method: Composition-based stats. Identities = 53/332 (15%), Positives = 103/332 (31%), Gaps = 55/332 (16%) Query: 72 GMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYEKLEEET---GQVVG 128 G+K L+E + G++ + L H GI K +D + + + E G Sbjct: 41 GIKTG-LIEMQDFAEGTSSRSTKLV---HGGIRYLK-TFDVEVVADTVGERAVVQGIAPH 95 Query: 129 FHQPGSIRLATTPVR------------VDEFKYQMTRTGWHATEQYLIEPEKIQEMFPLL 176 +P + L + ++ E Y + PE++ E P L Sbjct: 96 IPKPDPMLLPIYEDEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFL 155 Query: 177 NMNKVLAG----LYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARSDGTWDV 232 + + D + ++ A + GA L D V Sbjct: 156 KKEGLKGAGVYLDFRNNDARLVIDNI-----KKAAEDGAYLVSKMKAVGFLYEGDQIVGV 210 Query: 233 ETPQG------SMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYVVTSTISEVKALKR 286 + ++A ++N +G W +V + + P+ P + + K L Sbjct: 211 KARDLLTDEVIEIKAKLVINTSGPWVDKV-RNLNFTRPVSPKMRPTKGIHLVVDAKKLPV 269 Query: 287 ELPVLRDLEGSYYLRQERDGLLFGPYESQEKM---KVQDSWVTNGVPPGFGKELFESDLD 343 P +Y+ ++DG + + K + + P +E D+D Sbjct: 270 PQP-------TYFDTGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQE----DVD 318 Query: 344 RIMEHIKAAMEMVPV--LKKADIINVVNGPIT 373 +++ I P + ADI G Sbjct: 319 YLLDVIN---HRYPEANITLADIEASWAGLRP 347 >2RGH-A nrPDB Length = 571 Score = 46.7 bits (109), Expect = 4e-05, Method: Composition-based stats. Identities = 53/332 (15%), Positives = 103/332 (31%), Gaps = 55/332 (16%) Query: 72 GMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYEKLEEET---GQVVG 128 G+K L+E + G++ + L H GI K +D + + + E G Sbjct: 55 GIKTG-LIEMQDFAEGTSSRSTKLV---HGGIRYLK-TFDVEVVADTVGERAVVQGIAPH 109 Query: 129 FHQPGSIRLATTPVR------------VDEFKYQMTRTGWHATEQYLIEPEKIQEMFPLL 176 +P + L + ++ E Y + PE++ E P L Sbjct: 110 IPKPDPMLLPIYEDEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFL 169 Query: 177 NMNKVLAG----LYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARSDGTWDV 232 + + D + ++ A + GA L D V Sbjct: 170 KKEGLKGAGVYLDFRNNDARLVIDNI-----KKAAEDGAYLVSKMKAVGFLYEGDQIVGV 224 Query: 233 ETPQG------SMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYVVTSTISEVKALKR 286 + ++A ++N +G W +V + + P+ P + + K L Sbjct: 225 KARDLLTDEVIEIKAKLVINTSGPWVDKV-RNLNFTRPVSPKMRPTKGIHLVVDAKKLPV 283 Query: 287 ELPVLRDLEGSYYLRQERDGLLFGPYESQEKM---KVQDSWVTNGVPPGFGKELFESDLD 343 P +Y+ ++DG + + K + + P +E D+D Sbjct: 284 PQP-------TYFDTGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQE----DVD 332 Query: 344 RIMEHIKAAMEMVPV--LKKADIINVVNGPIT 373 +++ I P + ADI G Sbjct: 333 YLLDVIN---HRYPEANITLADIEASWAGLRP 361 >1KNR-A nrPDB Length = 540 Score = 46.0 bits (107), Expect = 7e-05, Method: Composition-based stats. Identities = 79/534 (14%), Positives = 150/534 (28%), Gaps = 73/534 (13%) Query: 43 ETQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPG 102 T + + +IIG G G+SLA LA V++L K +T GST++A G Sbjct: 2 NTLPEHSCDVLIIGSGAAGLSLALRLADQ--HQVIVLSKGPVTEGSTFYAQGGI------ 53 Query: 103 INLKKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQY 162 + ++ + +E+ G ++ + + Q+ Sbjct: 54 ---AAVFDETDSIDSHVEDTLIAGAGICDRHAVEFV--------------ASNARSCVQW 96 Query: 163 LIEPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSL 222 LI+ + + N + G H A P + Sbjct: 97 LIDQGVLFDTHIQPNGEESYHLTREGGHSHRRILHAADATGREVETTLVSKALNHPNIRV 156 Query: 223 KARSDGTWDVETPQGSMRANRIVNAAGFWAREV-------GKMIGLEHPLIPVQHQYVVT 275 R++ + + + + R V A W R K + L +QY Sbjct: 157 LERTNAVDLIVSDKIGLPGTRRVVGAWVWNRNKETVETCHAKAVVLATGGASKVYQYTTN 216 Query: 276 STISEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNGVPPGFGK 335 IS + + + + L + + + G Sbjct: 217 PDISSGDGIAMAWRAGCRVANLEFNQFHPTALYHPQARNFLLTEALRG-EGAYLKRPDGT 275 Query: 336 ELFESDLDRIM----EHIKAAM--EMVPVLKKADIINVVNGPITYSPDILPM-------- 381 +R + + A+ EM + +++ + P + PM Sbjct: 276 RFMPDFDERGELAPRDIVARAIDHEMKRLGADCMFLDISHKPADFIRQHFPMIYEKLLGL 335 Query: 382 -VGPHQGVRNYWVAIGFGYGIIHAGGVGKY----------LSDWILHGE---PPFDLIEL 427 + Q A + G + G+ +S LHG L+E Sbjct: 336 GIDLTQEPVPIVPAAHYTCGGVMVDDHGRTDVEGLYAIGEVSYTGLHGANLMASNSLLEC 395 Query: 428 DPNRYGKWTTTQYTEAKARESYGFNNIVGYPKEERFAGRPTQRVSGLYQRLESKCSMGFH 487 YG W+ + + R Y + P +E P +RV + E + M + Sbjct: 396 LV--YG-WSAAE--DITRRMPYAHDISTLPPWDESRVENPDERVVIQHNWHELRLFMWDY 450 Query: 488 AGWEQPHWFYKPGQDTQYRPSFRRTNWFEPVGSEYKQVMQRVAVTDLSPFGKFN 541 G + R R T + + Y + +L + Sbjct: 451 VGIVR-------TTKRLERALRRITMLQQEIDEYYAHFRVSNNLLELRNLVQVA 497 >1RP0-A nrPDB Length = 284 Score = 45.2 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 20/77 (25%), Positives = 33/77 (42%), Gaps = 2/77 (2%) Query: 51 ETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHY 110 + V++G G G+S AY ++K V ++E+S G W G + Sbjct: 41 DVVVVGAGSAGLSAAYEISKNPNVQVAIIEQSVSPGGGAW-LGGQLFSAMIVRKPAHLFL 99 Query: 111 DSIKLYEKLEEETGQVV 127 D I + E++T VV Sbjct: 100 DEIGVAYD-EQDTYVVV 115 >3CUK-A nrPDB Length = 347 Score = 44.8 bits (104), Expect = 1e-04, Method: Composition-based stats. Identities = 68/397 (17%), Positives = 122/397 (30%), Gaps = 76/397 (19%) Query: 52 TVIIGGGCVGVSLA------YHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINL 105 V+IG G +G+S A YH + V ++ +T AAGL + N Sbjct: 3 VVVIGAGVIGLSTALCIHERYHSVLQPLDIKVYADRFTPL-TTTDVAAGLWQPYLSDPNN 61 Query: 106 KKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQ---Y 162 + S + ++ L + H P + L + ++ Sbjct: 62 PQEADWSQQTFDYL------LSHVHSPNAENLGLFLISGYNLFHEAIPDPSWKDTVLGFR 115 Query: 163 LIEPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSL 222 + P ++ +MFP + ++ + L + G V S Sbjct: 116 KLTPREL-DMFP------DYGYGWFHTSLILEGKNYLQWLTERLTERGVKFFQR-KVESF 167 Query: 223 KARSDGTWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYVVTSTISEVK 282 + + A+ IVN G WA + + + L P + Q Sbjct: 168 EEVAREG-----------ADVIVNCTGVWAGALQR----DPLLQPGRGQ----------- 201 Query: 283 ALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNGVPPGFGKELFESDL 342 +K + P ++ + L + + ++ + G + S+L Sbjct: 202 IMKVDAPWMKH----FILTHDPERGIYNSPYIIPGTQ-------TVTLGGIFQLGNWSEL 250 Query: 343 DRIMEH---IKAAMEMVPVLKKADIINVVNGPITYSPD-----ILPMVGPHQ-------G 387 + I +H + + P LK A II G P GP G Sbjct: 251 NNIQDHNTIWEGCCRLEPTLKNARIIGERTGFRPVRPQIRLEREQLRTGPSNTEVIHNYG 310 Query: 388 VRNYWVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDL 424 Y + I +G + A G+ L + L PP L Sbjct: 311 HGGYGLTIHWGCALEAAKLFGRILEEKKLSRMPPSHL 347 >1F8S-A nrPDB Length = 498 Score = 44.4 bits (103), Expect = 2e-04, Method: Composition-based stats. Identities = 49/296 (16%), Positives = 88/296 (29%), Gaps = 76/296 (25%) Query: 40 LSAETQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAG-STWHAAGLTTY 98 L A + K VI+G G G+S AY LA AG + VL T+ Y Sbjct: 27 LKATSNPKH---VVIVGAGMAGLSAAYVLAGAGHQVTVLEASERPGGRVRTYRNEEAGWY 83 Query: 99 FHPGI-------------------NLKKIHYDSIKLYE---KLEEETGQVVGFHQPGSIR 136 + G L + ++ + + ++ G+V PG ++ Sbjct: 84 ANLGPMRLPEKHRIVREYIRKFDLRLNEFSQENDNAWYFIKNIRKKVGEVK--KDPGLLK 141 Query: 137 LATTPVR----------------VDEFKY----------QMTRTGWHATEQYLIEPEKIQ 170 P V+E K T + ++ + P + Sbjct: 142 YPVKPSEAGKSAGQLYEESLGKVVEELKRTNCSYILNKYDTYSTKEYLIKEGDLSPGAVD 201 Query: 171 EMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGA-----------RKCGALLKYPAPV 219 + LLN + + H D ++ R + + A V Sbjct: 202 MIGDLLNEDSGYYVSFIESLKHDDIFAYEKRFDEIVDGMDKLPTAMYRDIQDKVHFNAQV 261 Query: 220 TSLKARSDGTWDV------ETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQ 269 ++ V ETP S+ A+ ++ ++I PL+P + Sbjct: 262 IKIQQNDQKVTVVYETLSKETP--SVTADYVIVCT---TSRAVRLIKFNPPLLPKK 312 >3R9U-A nrPDB Length = 315 Score = 43.6 bits (101), Expect = 3e-04, Method: Composition-based stats. Identities = 16/53 (30%), Positives = 26/53 (49%), Gaps = 3/53 (5%) Query: 51 ETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGI 103 + IIGGG G+S + + G+K+VV+ EK T + +PG+ Sbjct: 6 DVAIIGGGPAGLSAGLYATRGGLKNVVMFEKGMPGGQITSSSE---IENYPGV 55 >3ISH-A nrPDB Length = 311 Score = 43.6 bits (101), Expect = 4e-04, Method: Composition-based stats. Identities = 17/68 (25%), Positives = 31/68 (45%), Gaps = 3/68 (4%) Query: 51 ETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHY 110 + IIGGG G+S + + G+K+ VL EK T + +PG+ Sbjct: 3 DCAIIGGGPAGLSAGLYATRGGVKNAVLFEKGMPGGQITGSSE---IENYPGVKEVVSGL 59 Query: 111 DSIKLYEK 118 D ++ +++ Sbjct: 60 DFMQPWQE 67 >1VE9-A nrPDB Length = 347 Score = 43.6 bits (101), Expect = 4e-04, Method: Composition-based stats. Identities = 68/396 (17%), Positives = 121/396 (30%), Gaps = 74/396 (18%) Query: 52 TVIIGGGCVGVSLA------YHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINL 105 V+IG G +G+S A YH + V ++ +T AAGL + + Sbjct: 3 VVVIGAGVIGLSTALCIHERYHSVLQPLDVKVYADRFTP-FTTTDVAAGLWQPYTSEPSN 61 Query: 106 KKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYL-- 163 + + + + L G P + + TPV + + + L Sbjct: 62 PQEANWNQQTFNYLLSHIG------SPNAANMGLTPVSGYNLFREAVPDPYW-KDMVLGF 114 Query: 164 --IEPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTS 221 + P ++ +MFP + ++ L + G V S Sbjct: 115 RKLTPREL-DMFPDYRYG------WFNTSLILEGRKYLQWLTERLTERGVKFFLR-KVES 166 Query: 222 LKARSDGTWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYV-VTSTISE 280 + E +G A+ I+N G WA + + L P + Q + V + + Sbjct: 167 FE---------EVARGG--ADVIINCTGVWAGVLQP----DPLLQPGRGQIIKVDAPWLK 211 Query: 281 VKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNGVPPGFGKELFES 340 + +L R + S Y+ +Q + G E+ Sbjct: 212 NFIITHDLE--RGIYNSPYIIP----------------GLQAVTLGGTFQVGNWNEINNI 253 Query: 341 DLDRIMEHIKAAMEMVPVLKKADIINVVNGPITYSP------DILPMVGPHQG------V 388 + + + P LK A I+ G P + L + Sbjct: 254 QDHNTI--WEGCCRLEPTLKDAKIVGEYTGFRPVRPQVRLEREQLRFGSSNTEVIHNYGH 311 Query: 389 RNYWVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDL 424 Y + I +G + A GK L + L PP L Sbjct: 312 GGYGLTIHWGCALEVAKLFGKVLEERNLLTMPPSHL 347 >4REP-A nrPDB Length = 495 Score = 43.6 bits (101), Expect = 4e-04, Method: Composition-based stats. Identities = 17/84 (20%), Positives = 37/84 (44%), Gaps = 3/84 (3%) Query: 165 EPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKA 224 P + + ++ ++ G Y P G + ++ +L A+K G ++ VT++ Sbjct: 196 SPYQTPGIMTMIPHLELGLGTYYPDGGM---HRISQSLFELAQKVGVKFRFRESVTNITT 252 Query: 225 RSDGTWDVETPQGSMRANRIVNAA 248 + VET GS ++ +V+ Sbjct: 253 SKNKVTGVETKNGSYLSDLVVSNM 276 >3KVE-A nrPDB Length = 486 Score = 43.3 bits (100), Expect = 4e-04, Method: Composition-based stats. Identities = 48/286 (16%), Positives = 87/286 (30%), Gaps = 77/286 (26%) Query: 52 TVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAG--STWHAAGLTTYFHPGI------ 103 V++G G G+S AY LA AG K V +LE SE G T + Y + G Sbjct: 36 VVVVGAGMSGLSAAYVLAGAGHK-VTVLEASERAGGRVRTHRNSKEGWYANLGPMRIPEK 94 Query: 104 -------------NLKKIHYDSIKLYE---KLEEETGQVVGFHQPGSIRLATTPVRVDEF 147 NL + ++ + + + G+V PG ++ P + Sbjct: 95 HRIVREYIRKFGLNLNEFSQENDNAWYFIKNIRKRVGEVN--KDPGLLKYPVKPSEEGKS 152 Query: 148 --------------------------KYQMTRTGWHATEQYLIEPEKIQEMFPLLNMNKV 181 KY T + ++ + P + + LLN + Sbjct: 153 AGQLYEESLGSAVKDLKRTNCSYILNKYDTYSTKEYLIKEGNLSPGAVDMIGDLLNEDSG 212 Query: 182 LAGLYNPGDGHIDPYSLTMALAAGARKCGA--------------LLKYPAPVTSLKARSD 227 + + + G +K+ A V ++ ++ Sbjct: 213 YYVSFIES---LKHDDIFAYEKRFDEIVGGMDQLPTSMYRAIEEKVKFNARVIKIQQNAN 269 Query: 228 GTW-DVETPQ---GSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQ 269 +TP+ S A+ ++ + I E PL P + Sbjct: 270 QVTVTYQTPEKDTSSNTADYVIVCT---TSRAARRIQFEPPLPPKK 312 >6BRD-A nrPDB Length = 476 Score = 42.9 bits (99), Expect = 6e-04, Method: Composition-based stats. Identities = 45/231 (19%), Positives = 79/231 (34%), Gaps = 60/231 (25%) Query: 50 AETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIH 109 + +++GGG G+ LA L G++ +VL +++E T S + +H Sbjct: 2 FDVIVVGGGPTGLMLAGELRLHGVRVLVLEKETEPTRQS---------------RAQGLH 46 Query: 110 YDSIKLY--EKLEEETGQVVGFHQPGSIR--LATTPVRVDEFKYQMTRTGWHATEQYLIE 165 SI++ L E + G LAT+ + + L Sbjct: 47 VRSIEVMAQRGLLERFLERGHTVAVGGFFAGLATSWPERLDTAHSY----------VLAV 96 Query: 166 PEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKAR 225 P+ I E LA A GA ++ + L+ Sbjct: 97 PQVITE----------------------------QLLAEHATALGAEIRRGRALVGLRQD 128 Query: 226 SDGTWDVETPQGS-MRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYVVT 275 DG V+ G +RA +V G V K++G+ P P + + ++ Sbjct: 129 EDGVT-VDLADGEQLRARYVVGCDGG-RSTVRKLLGVAFPGEPSRVETLLG 177 >5MJK-A nrPDB Length = 327 Score = 42.5 bits (98), Expect = 8e-04, Method: Composition-based stats. Identities = 26/113 (23%), Positives = 43/113 (38%), Gaps = 3/113 (2%) Query: 47 KDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLK 106 + + + VIIG G G++ A + A++ MK +LLE+ A + I Sbjct: 22 EKKYDVVIIGSGPAGMTAAMYTARSEMK-TLLLERGVPGGQMNNTAEIENYPGYETIMGP 80 Query: 107 KIHYDSIKLYEKLEEE--TGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWH 157 ++ + E L E G V G G + T K + TG + Sbjct: 81 ELSMKMAEPLEGLGVENAYGFVTGIEDHGDYKKIITEDDEFITKSIIIATGAN 133 >4DGK-A nrPDB Length = 501 Score = 41.7 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 39/220 (17%), Positives = 70/220 (31%), Gaps = 31/220 (14%) Query: 52 TVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGI-------- 103 T +IG G G++LA L AG+ V+LLE+ + G + F G Sbjct: 4 TTVIGAGFGGLALAIRLQAAGI-PVLLLEQRDKPGGRAYVYEDQGFTFDAGPTVITDPSA 62 Query: 104 --NLKKIHYDSIKLYEKLEE-ETGQVVGFHQPGSIRL------------ATTPVRVDEFK 148 L + +K Y +L + + P V+ ++ Sbjct: 63 IEELFALAGKQLKEYVELLPVTPFYRLCWESGKVFNYDNDQTRLEAQIQQFNPRDVEGYR 122 Query: 149 YQMTRTGWHATEQYLIEP-------EKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMA 201 + + E YL + P L + +Y+ +I+ L A Sbjct: 123 QFLDYSRAVFKEGYLKLGTVPFLSFRDMLRAAPQLAKLQAWRSVYSKVASYIEDEHLRQA 182 Query: 202 LAAGARKCGALLKYPAPVTSLKARSDGTWDVETPQGSMRA 241 + + G + + +L + W V P+G A Sbjct: 183 FSFHSLLVGGNPFATSSIYTLIHALEREWGVWFPRGGTGA 222 >5KXJ-A nrPDB Length = 557 Score = 41.7 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 36/210 (17%), Positives = 67/210 (31%), Gaps = 25/210 (11%) Query: 44 TQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGI 103 T + + +IIG G G+SLA LA+ V++L K ++ GST++A G Sbjct: 3 TTPELSCDVLIIGSGAAGLSLALRLAEK--HKVIVLSKGPVSEGSTFYAQGGI------- 53 Query: 104 NLKKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYL 163 + ++ + +E+ G ++ + Q+L Sbjct: 54 --AAVFDETDSIASHVEDTLIAGAGICDRHAVEFV--------------ASNARTCVQWL 97 Query: 164 IEPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLK 223 I+ + + N + G H A P + Sbjct: 98 IDQGVLFDTHVQPNGKESYHLTREGGHSHRRILHAADATGKEVETTLVSRAQNHPNIQVL 157 Query: 224 ARSDGTWDVETPQGSMRANRIVNAAGFWAR 253 RS+ + + + + R V A W R Sbjct: 158 ERSNAVDLIISDKMGLPGPRRVVGAWIWNR 187 >2CVJ-A nrPDB Length = 180 Score = 41.7 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 23/102 (22%), Positives = 42/102 (41%), Gaps = 6/102 (5%) Query: 51 ETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHA---AGLTTYFHPGINLKK 107 + +++GGG G+S A LA+AG+K V++L+ GL L++ Sbjct: 3 DVIVVGGGPSGLSAALFLARAGLK-VLVLDGGRSKVKGVSRVPNYPGLLDEPSGEELLRR 61 Query: 108 IHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKY 149 + + + E G V G G + T V++ + Sbjct: 62 LEAHARR--YGAEVRPGVVKGVRDMGGVFEVETEEGVEKAER 101 >1NRK-A nrPDB Length = 328 Score = 41.3 bits (95), Expect = 0.002, Method: Composition-based stats. Identities = 42/233 (18%), Positives = 83/233 (35%), Gaps = 21/233 (9%) Query: 542 IKGQDSIRLLDHLFANVIPKVG--FTNISHMLTPKGRVYAELTVSHQSPGEFLLITGSGS 599 I G DS + + + ++ ++ KG++++ L + G + S Sbjct: 35 ITGADSEKYMQGQVTADVSQMAEDQHLLAAHCDAKGKMWSNLRLFRDGDGFAWIERRSV- 93 Query: 600 ELHDLRWIEEEAVKGGYDVEIKNITDELGVLGVAGPQARKVLQKLTSEDLSDDVFKFLQT 659 L +++ AV + DE +LGVAG QAR L L SE L + ++ Sbjct: 94 REPQLTELKKYAVFSKVTI---APDDERVLLGVAGFQARAALANLFSE-LPSKEKQVVKE 149 Query: 660 KSLKVSNIPVTAIRISYTGELGWELYHRREDSVALYDAIMNAGQEEGIDNFGTYAMNALR 719 + + A R + + + L D + + + AL Sbjct: 150 GATTLLWFEHPAER--------FLIVTDEATANMLTDKLRGEAELNNSQQW-----LALN 196 Query: 720 LEKAFRAWGLEMNCDTNPLEAGLEYFVKLN-KPADFIGKQALKQIKAKGLKRR 771 +E F + P L+ ++ K + G++ + + K +G +R Sbjct: 197 IEAGFPVIDAANSGQFIPQATNLQALGGISFKKGCYTGQEMVARAKFRGANKR 249 >1C0L-A nrPDB Length = 363 Score = 41.3 bits (95), Expect = 0.002, Method: Composition-based stats. Identities = 51/265 (19%), Positives = 85/265 (32%), Gaps = 45/265 (16%) Query: 52 TVIIGGGCVGVSLAYHLAKAGMKDVVL-----LEKSELTAGSTWHAAGLTTYFHP--GIN 104 V++G G +G+S A LA+ G +L + S T S W A T + G Sbjct: 9 VVVLGSGVIGLSSALILARKGYSVHILARDLPEDVSSQTFASPWAGANWTPFMTLTDGPR 68 Query: 105 LKKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLI 164 K + K + +L TG + G+ R A + + Sbjct: 69 QAKWEESTFKKWVELVP-TGHAMWL--KGTRRFAQNEDGLLG-----HWYKDITPNYRPL 120 Query: 165 EPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKA 224 + + Y+ H Y LA +K GA VTSL+ Sbjct: 121 PSSECP--------PGAIGVTYDTLSVHAPKY--CQYLARELQKLGAT-FERRTVTSLEQ 169 Query: 225 RSDGTWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYVVTSTISEVKAL 284 DG A+ +VNA G A+ + + + P++ Q V+ + + + Sbjct: 170 AFDG------------ADLVVNATGLGAKSIAGID--DQAAEPIRGQTVLVKSPCKRCTM 215 Query: 285 KRELPVLRDLEGSYYLRQERDGLLF 309 P Y+ G + Sbjct: 216 DSSDPAS-----PAYIIPRPGGEVI 235 >1NAA-A nrPDB Length = 541 Score = 41.3 bits (95), Expect = 0.002, Method: Composition-based stats. Identities = 21/74 (28%), Positives = 34/74 (45%), Gaps = 7/74 (9%) Query: 50 AETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIH 109 + +I+G G G+ A L++AG K V+LLE+ + T TY P + Sbjct: 3 YDYIIVGAGPGGIIAADRLSEAG-KKVLLLERGGPSTKQTG-----GTYVAPWATSSGLT 56 Query: 110 -YDSIKLYEKLEEE 122 +D L+E L + Sbjct: 57 KFDIPGLFESLFTD 70 >3ATQ-A nrPDB Length = 453 Score = 40.9 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 13/35 (37%), Positives = 22/35 (62%) Query: 49 RAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSE 83 + + +IIGGG G S AY L++ G+K +++ K Sbjct: 6 KYDVLIIGGGFAGSSAAYQLSRRGLKILLVDSKPW 40 >5NCC-A nrPDB Length = 594 Score = 40.6 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 36/208 (17%), Positives = 69/208 (33%), Gaps = 20/208 (9%) Query: 41 SAETQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKS-ELTAGSTWHAAGLTTYF 99 S+ + + +++GGG LA L+ G K V++LE + T+ A +T F Sbjct: 15 SSSPVAGQKYDYILVGGGTAACVLANRLSADGSKRVLVLEAGPDNTSRDVKIPAAITRLF 74 Query: 100 HPGINLKKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKY-QMTRTGWHA 158 ++ L+ +L+E+ + + G + ++ + Sbjct: 75 RSPLDWN--------LFSELQEQLAERQIYMARGRLLGGSSATNATLYHRGAAGDYDAWG 126 Query: 159 TEQYLIEPEKIQEMFPLLNMNKVLA-GLYNPGDGHIDPYS-------LTMALAAGARKCG 210 E + E + F N G Y+ G + + L A A + G Sbjct: 127 VEGW--SSEDVLSWFVQAETNADFGPGAYHGSGGPMRVENPRYTNKQLHTAFFKAAEEVG 184 Query: 211 ALLKYPAPVTSLKARSDGTWDVETPQGS 238 S GT+ V +G+ Sbjct: 185 LTPNSDFNDWSHDHAGYGTFQVMQDKGT 212 >3FPZ-A nrPDB Length = 326 Score = 40.6 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 22/99 (22%), Positives = 42/99 (42%), Gaps = 6/99 (6%) Query: 50 AETVIIGGGCVGVSLAYHLAKAGMK-DVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKI 108 ++ +I+G G G+S AY +AK V ++E S G +W L F + K Sbjct: 66 SDVIIVGAGSSGLSAAYVIAKNRPDLKVCIIESSVAPGGGSWLGGQL---FSAMVMRKPA 122 Query: 109 HYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEF 147 H +L ++ E + ++ ++T +V + Sbjct: 123 HLFLQEL--EIPYEDEGDYVVVKHAALFISTVLSKVLQL 159 >4C5O-A nrPDB Length = 357 Score = 40.2 bits (92), Expect = 0.004, Method: Composition-based stats. Identities = 13/39 (33%), Positives = 22/39 (56%) Query: 48 DRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTA 86 D + V+IGGG G+S Y L ++G+ V+L ++ Sbjct: 2 DSVDVVVIGGGQSGLSAGYFLRRSGLSYVILDAEASPGG 40 >3MJ4-A nrPDB Length = 397 Score = 40.2 bits (92), Expect = 0.004, Method: Composition-based stats. Identities = 22/104 (21%), Positives = 40/104 (38%), Gaps = 1/104 (0%) Query: 28 SVCGREGEEKPPLSAETQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAG 87 S E E+ + E Q + +I+G G G LA LA +G + V+++++ G Sbjct: 8 SAVTNERTEQTNTTNEQQESKGFDYLIVGAGFAGSVLAERLASSGQR-VLIVDRRPHIGG 66 Query: 88 STWHAAGLTTYFHPGINLKKIHYDSIKLYEKLEEETGQVVGFHQ 131 + + H +S ++E L T H+ Sbjct: 67 NAYDCYDDAGVLIHPYGPHIFHTNSKDVFEYLSRFTEWRPYQHR 110 >3WE0-A nrPDB Length = 580 Score = 39.8 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 37/214 (17%), Positives = 69/214 (32%), Gaps = 13/214 (6%) Query: 44 TQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGI 103 + E I+G G G+ AY L K G+K V + E S++ A T + Sbjct: 60 PAARHGEEVAIVGAGIAGLVAAYELMKLGLKPV-VYEASKMGGRLRSQAFNGTDGIIAEL 118 Query: 104 NLKKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWH------ 157 + S Y +++ + F P + +T + ++ Y + Sbjct: 119 GGMRFPVSSTAFYHYVDKLGLETKPFPNPLTPASRSTVIDLEGQTYYAEKAADLPALFQE 178 Query: 158 ATEQY---LIEPEKIQEMFPLLNMNKV--LAGLYNPGDGHIDPYSLTMALAAGARKCGAL 212 T+ + L + ++ + V L L+N + A ++ L Sbjct: 179 VTDAWADALESGARFGDIQQAIRDRDVPRLKELWN-TLVPLWDDRTFYDFVATSKAFAKL 237 Query: 213 LKYPAPVTSLKARSDGTWDVETPQGSMRANRIVN 246 V G WD + P + R+V Sbjct: 238 SFQHREVFGQVGFGTGGWDSDFPNSMLEIFRVVM 271 >3L1R-A nrPDB Length = 478 Score = 39.8 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 57/375 (15%), Positives = 112/375 (29%), Gaps = 72/375 (19%) Query: 52 TVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHA---------AGLTTYFHPG 102 +++G G G+S A L++AG+ D+++LE ++ G G Sbjct: 7 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANWVEGVNG 66 Query: 103 INLKKIH-----------------YDSIKLYEK---------LEEETGQVVGFHQPGSIR 136 + I Y + +Y++ +++ + G Sbjct: 67 GKMNPIWPIVNSTLKLRNFRSDFDYLAQNVYKEDGGVYDEDYVQKRIELADSVEEMGEKL 126 Query: 137 LA--TTPVRVDEFKYQMTRTGWHAT----------------EQYLIEPEKIQEM---FPL 175 A R D M R H + EP ++ + PL Sbjct: 127 SATLHASGRDDMSILAMQRLNEHQPNGPATPVDMVVDYYKFDYEFAEPPRVTSLQNTVPL 186 Query: 176 LNMNKVLAGLY---NPGDGHIDPYSLTMALAAGARKCGA----LLKYPAPVTSLKARSDG 228 + +Y + Y L K G L+ V +K G Sbjct: 187 ATFSDFGDDVYFVADQRGYEAVVYYLAGQYLKTDDKSGKIVDPRLQLNKVVREIKYSPGG 246 Query: 229 TWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYVVTS-----TISEVKA 283 V+T S+ + V + +I + L + + + T+ +K Sbjct: 247 VT-VKTEDNSVYSADYVMVSASLGVLQSDLIQFKPKLPTWKVRAIYQFDMAVYTMIFLKF 305 Query: 284 LKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNGVPPGFGKELF-ESDL 342 ++ P + E Y R +G ++ EK + + V + + +SD Sbjct: 306 PRKFWPEGKGREFFLYASSRRG--YYGVWQEFEKQYPDANVLLVTVTDEESRRIEQQSDE 363 Query: 343 DRIMEHIKAAMEMVP 357 E ++ +M P Sbjct: 364 QTKAEIMQVLRKMFP 378 >4Y4M-A nrPDB Length = 290 Score = 39.4 bits (90), Expect = 0.006, Method: Composition-based stats. Identities = 15/31 (48%), Positives = 20/31 (64%) Query: 50 AETVIIGGGCVGVSLAYHLAKAGMKDVVLLE 80 A+ VI+G G G++ A +LAK G K VVL Sbjct: 60 ADVVIVGAGPSGLTCARYLAKEGFKVVVLER 90 >1REO-A nrPDB Length = 486 Score = 39.4 bits (90), Expect = 0.006, Method: Composition-based stats. Identities = 49/298 (16%), Positives = 90/298 (30%), Gaps = 80/298 (26%) Query: 40 LSAETQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAG--STWHAAGLTT 97 L A + K V++G G G+S AY L+ AG V +LE SE G T+ Sbjct: 27 LKATSNPKH---VVVVGAGMSGLSAAYVLSGAG-HQVTVLEASERAGGRVRTYRNDKEDW 82 Query: 98 YFHPGI-------------------NLKKIHYDSIKLYE---KLEEETGQVVGFHQPGSI 135 Y + G L + ++ + + + G+V PG + Sbjct: 83 YANLGPMRLPEKHRIVREYIRKFGLQLNEFSQENDNAWYFIKNIRKRVGEVK--KDPGVL 140 Query: 136 RLATTPVR----------------VDEFKY----------QMTRTGWHATEQYLIEPEKI 169 + P V+E K T + ++ + P + Sbjct: 141 KYPVKPSEEGKSAGQLYEESLGKVVEELKRTNCSYILNKYDTYSTKEYLLKEGNLSPGAV 200 Query: 170 QEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGA--------------LLKY 215 + L+N + + P + + G + Sbjct: 201 DMIGDLMNEDSGYYVSF-PES--LRHDDIFAYEKRFDEIVGGMDKLPTSMYRAIEEKVHL 257 Query: 216 PAPVTSLKARSDGTWDV-ETPQ---GSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQ 269 A V ++ ++ V +TP S+ A+ ++ + I E PL P + Sbjct: 258 NAQVIKIQKNAEKVTVVYQTPAKEMASVTADYVIVCT---TSRATRRIKFEPPLPPKK 312 >4IV9-A nrPDB Length = 557 Score = 39.4 bits (90), Expect = 0.006, Method: Composition-based stats. Identities = 28/130 (21%), Positives = 42/130 (32%), Gaps = 16/130 (12%) Query: 52 TVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTW---------HAAGLTTYFHPG 102 I+G G G+ A L +AG+KDVVL E + G W Sbjct: 41 VAIVGAGISGLVAATELLRAGVKDVVLYESRDRIGGRVWSQVFDQTRPRYIAEMGAMRFP 100 Query: 103 INLKKIHYDSIKL---YEKLEEETGQV-VGFHQPGSIRLATTPVRVDEFKYQMTRTGWHA 158 + + + K + G V H G + E ++ GW + Sbjct: 101 PSATGLFHYLKKFGISTSTTFPDPGVVDTELHYRGKRYHWPAGKKPPELFRRV-YEGWQS 159 Query: 159 T--EQYLIEP 166 E YL+E Sbjct: 160 LLSEGYLLEG 169 >2JB2-A nrPDB Length = 489 Score = 39.4 bits (90), Expect = 0.006, Method: Composition-based stats. Identities = 21/70 (30%), Positives = 29/70 (41%), Gaps = 1/70 (1%) Query: 47 KDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLK 106 K V++GGG G+ A+ L KAG K V +LE G W A G + + Sbjct: 9 KGSHSVVVLGGGPAGLCSAFELQKAGYK-VTVLEARTRPGGRVWTARGGSEETDLSGETQ 67 Query: 107 KIHYDSIKLY 116 K + Y Sbjct: 68 KCTFSEGHFY 77 >5MOG-A nrPDB Length = 497 Score = 38.6 bits (88), Expect = 0.012, Method: Composition-based stats. Identities = 20/75 (26%), Positives = 32/75 (42%), Gaps = 8/75 (10%) Query: 45 QWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAG--------STWHAAGLT 96 Q + VI G G G+S A +LA AG K ++L + L W+ GL Sbjct: 13 QPTKPLQVVIAGAGLAGLSTAKYLADAGHKPILLEARDVLGGKIAAWKDEDGDWYETGLH 72 Query: 97 TYFHPGINLKKIHYD 111 +F N++ + + Sbjct: 73 IFFGAYPNIQNLFGE 87 >4K5R-A nrPDB Length = 536 Score = 38.6 bits (88), Expect = 0.012, Method: Composition-based stats. Identities = 27/182 (14%), Positives = 53/182 (29%), Gaps = 11/182 (6%) Query: 148 KYQMTRTGWHATEQYLIEPEKIQEMFPLLN-----MNKVLAGLYNPGDGHIDPYSLTMAL 202 + +E ++ + P ++ L +P + L Sbjct: 61 IRTVETLDLRGLLDRFLEGTQVAKGLPFAGIFTQGLDFGLVDTRHPYTALVPQSRTEALL 120 Query: 203 AAGARKCGALLKYPAPVTSLKARSDGT-WDVETPQGSM--RANRIVNAAGFWAREVGKMI 259 A AR+ GA ++ VT L+ ++ V P G RA V G V ++ Sbjct: 121 AEHAREAGAEIRRGHEVTGLRQDAEAVEVTVAGPSGPYRVRARYAVGCDGG-RSTVRRLA 179 Query: 260 GLEHPLIPVQHQYVVTSTISEVKALKRELPVLRDLEGSYYLRQER--DGLLFGPYESQEK 317 G+ P + ++ + + + R D E ++ Y Sbjct: 180 GIGFPGTEATVRALIGYVTTPEREVPRRWERTPDGILVLAFPPEGGLGRVVVIEYTGHSP 239 Query: 318 MK 319 Sbjct: 240 AA 241 >1SEZ-A nrPDB Length = 504 Score = 38.6 bits (88), Expect = 0.013, Method: Composition-based stats. Identities = 16/93 (17%), Positives = 29/93 (31%) Query: 39 PLSAETQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTY 98 P + E + +IG G G++ AY L G+ V + + + + Sbjct: 3 PSAGEDKHSSAKRVAVIGAGVSGLAAAYKLKIHGLNVTVFEAEGKAGGKLRSVSQDGLIW 62 Query: 99 FHPGINLKKIHYDSIKLYEKLEEETGQVVGFHQ 131 + + D L + L Q Q Sbjct: 63 DEGANTMTESEGDVTFLIDSLGLREKQQFPLSQ 95 >1KSU-A nrPDB Length = 571 Score = 38.2 bits (87), Expect = 0.014, Method: Composition-based stats. Identities = 51/340 (15%), Positives = 109/340 (32%), Gaps = 33/340 (9%) Query: 63 SLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSIKLYEKLEEE 122 S A +G K + L+EK + G+ AAG K DS +L + + Sbjct: 140 SAAISATDSGAKVI-LIEKEPVIGGNAKLAAGGMNAAWTDQQKAKKITDSPELMFEDTMK 198 Query: 123 TGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLIEPEKIQEMFPLLNMNKVL 182 GQ + + P +++ ++ + + MT G T+ ++ + Sbjct: 199 GGQNI--NDPALVKVLSSHSK--DSVDWMTAMGADLTDVGMMGGASVNRA---------- 244 Query: 183 AGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARSDGTWDVETPQGSM--- 239 + P G + L A K L+ + GT +G Sbjct: 245 ---HRPTGGAGVGAHVVQVLYDNAVKRNIDLRMNTRGIEVLKDDKGTVKGILVKGMYKGY 301 Query: 240 ---RANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYVVTSTISEVKALKRELPVLRDLEG 296 +A+ ++ A G +A+ ++ L+ L + + + L+D++ Sbjct: 302 YWVKADAVILATGGFAKNNERVAKLDPSLKGFISTNQPGAVGDGLDVAENAGGALKDMQ- 360 Query: 297 SYYLRQERDGLLFGPYESQEKMKVQDSWVTNGVPPGFGKELFESDLDRIMEHIKAAMEMV 356 Y++ + G E ++ + + N F E+ D + Sbjct: 361 --YIQAHPTLSVKGGVMVTEAVRGNGAILVNREGKRFVNEITTRDKASAAILAQTGKSAY 418 Query: 357 PVLKK------ADIINVVNGPITYSPDILPMVGPHQGVRN 390 + + I + + + D L +G +G+ Sbjct: 419 LIFDDSVRKSLSKIDKYIGLGVAPTADSLVKLGKMEGIDG 458 >3IHG-A nrPDB Length = 535 Score = 38.2 bits (87), Expect = 0.015, Method: Composition-based stats. Identities = 39/211 (18%), Positives = 68/211 (32%), Gaps = 49/211 (23%) Query: 51 ETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHY 110 + +++G G G+S A LA+ G++ +V+ + AAG + + + Sbjct: 7 DVLVVGAGLGGLSTAMFLARQGVRVLVVERR--PGLSPYPRAAGQNPRTMELLRIGGVAD 64 Query: 111 DSIKLYEKLEEETGQVVGFHQ--PGSIRLATTPVRVDEFKYQMT---RTGWHATEQYLIE 165 + ++ + + V+ + G I L T D+ GW Q +E Sbjct: 65 EVVRADDIRGTQGDFVIRLAESVRGEI-LRTVSESFDDMVAATEPCTPAGWAMLSQDKLE 123 Query: 166 PEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKA- 224 P L A ARK G +++ + S + Sbjct: 124 P----------------------------------ILLAQARKHGGAIRFGTRLLSFRQH 149 Query: 225 RSDGTWDVET----PQGSM--RANRIVNAAG 249 D V P G RA +V A G Sbjct: 150 DDDAGAGVTARLAGPDGEYDLRAGYLVGADG 180 >4UIR-A nrPDB Length = 646 Score = 38.2 bits (87), Expect = 0.015, Method: Composition-based stats. Identities = 16/78 (20%), Positives = 32/78 (41%), Gaps = 5/78 (6%) Query: 48 DRAETVIIGGGCVGVSLAYHLAKAG---MKDVVLLEKSELTAGS--TWHAAGLTTYFHPG 102 D ++ IIG G G+S AY+ + G K++ LE+ + GS G Sbjct: 61 DNSKIYIIGSGIAGMSAAYYFIRDGHVPAKNITFLEQLHIDGGSLDGAGNPTDGYIIRGG 120 Query: 103 INLKKIHYDSIKLYEKLE 120 + + + +++ + Sbjct: 121 REMDMTYENLWDMFQDIP 138 >4BK3-A nrPDB Length = 424 Score = 38.2 bits (87), Expect = 0.017, Method: Composition-based stats. Identities = 38/233 (16%), Positives = 71/233 (30%), Gaps = 27/233 (11%) Query: 197 SLTMALAAGARKCGALLKYPAPVTSLKARSDGTWDVETPQGSMRANRIVNAAGFWAREVG 256 L L AR GA L VT + D V T G I + Sbjct: 112 DLHATLVDAARAAGAELHTGVTVTDVITEGDKAI-VSTDDGRTHEADIALGMDGLKSRLR 170 Query: 257 KMIGLEHPLIPVQHQYVVTSTISEVKALKRELPVLRDLEG--SYYLR-QERDGLLFGPYE 313 + I + P+ Y T+ +V L ++ + G ++++ R G + Sbjct: 171 EKISGDEPVSSGYAAYRGTTPYRDV-ELDEDIEDVVGYIGPRCHFIQYPLRGGEMLNQVA 229 Query: 314 SQEKMKVQDSWVTNGVPPGFGKELFESDLDRIMEHIKAAMEMVPVLKKADIINVVNGPIT 373 E ++ G P E E E+++ ++ + + Sbjct: 230 VFESPGFKNGIENWGGP-----EELEQAYAHCHENVRRGIDYL-------WKDRWWPMYD 277 Query: 374 YSP-----DILPMV---GPHQGVRNYWVAIGFGYGIIHAGGVGKYLSDWILHG 418 P D ++ H ++ ++A G I A + Y ++ G Sbjct: 278 REPIENWVDGRMILLGDAAHPPLQ--YLASGAVMAIEDAKCLADYAAEDFSTG 328 >4EIQ-A nrPDB Length = 549 Score = 37.5 bits (85), Expect = 0.025, Method: Composition-based stats. Identities = 45/230 (19%), Positives = 76/230 (33%), Gaps = 50/230 (21%) Query: 51 ETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHY 110 + +I+GGG VG++LA LA + +V+ AG T HP + I Sbjct: 28 DVLILGGGPVGMALALDLAHRQVGHLVV-------------DAGDGTITHP--KVSTIGP 72 Query: 111 DSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLIEPEKIQ 170 S++L+ G V + G H + + Sbjct: 73 RSMELF----RRWG-------------------VAKQIRTAGWPGDHPLDAAWVTRVGGH 109 Query: 171 EMF--PLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARSDG 228 E++ PL + + P I P A G L+ + + S + R D Sbjct: 110 EVYRIPLGTADTRATPEHTPEPDAICPAH--WLAPLLAEAVGERLRTRSRLDSFEQRDDH 167 Query: 229 T----WDVET-PQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYV 273 D+ T ++ A +V G + K +G++ P P V Sbjct: 168 VRATITDLRTGATRAVHARYLVACDGA-SSPTRKALGIDAP--PRHRTQV 214 >3CGD-A nrPDB Length = 480 Score = 37.5 bits (85), Expect = 0.026, Method: Composition-based stats. Identities = 39/254 (15%), Positives = 74/254 (29%), Gaps = 61/254 (24%) Query: 49 RAETVIIGGGCVGVSLAYHLAKAGMK-DVVLLEKSE---------LTAGSTWHAAGLTTY 98 VIIGG G+S A + + +VV LEK E S A+ Sbjct: 36 SMNYVIIGGDAAGMSAAMQIVRNDENANVVTLEKGEIYSYAQCGLPYVISGAIASTEKLI 95 Query: 99 FHPGINLKKIHYDSIKLYEKLEE-------------ETGQVVGFH--------------- 130 + + K+ ++ + +T V F Sbjct: 96 ARNVKTFRDKYGIDAKVRHEVTKVDTEKKIVYAEHTKTKDVFEFSYDRLLIATGVRPVMP 155 Query: 131 -----QPGSIRLATTPVRVDEFKYQMTRTGW--------HATEQYLIEPE-KIQEMFPLL 176 + L T + + A + E ++ + ++ Sbjct: 156 EWEGRDLQGVHLLKTIPDAERILKTLETNKVEDVTIIGGGAIGLEMAETFVELGKKVRMI 215 Query: 177 NMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARSDGTWDVETPQ 236 N + +Y DG + Y + A K + V + K + VET + Sbjct: 216 ERNDHIGTIY---DGDMAEY-----IYKEADKHHIEILTNENVKAFKGN-ERVEAVETDK 266 Query: 237 GSMRANRIVNAAGF 250 G+ +A+ ++ + G Sbjct: 267 GTYKADLVLVSVGV 280 >3BI4-A nrPDB Length = 516 Score = 37.5 bits (85), Expect = 0.027, Method: Composition-based stats. Identities = 37/273 (13%), Positives = 80/273 (29%), Gaps = 58/273 (21%) Query: 52 TVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGST-------WHAAGLTTYFHPGIN 104 +IIG G G+ A L + G++D ++LE + G + +H Sbjct: 11 VIIIGAGIAGLKAASTLHQNGIQDCLVLEARDRVGGRLQTVTGYQGRKYDIGASWHHDTL 70 Query: 105 LKKIHYDSIKLYEK----------------------LEEETGQVVGFHQPGSIRLATTP- 141 + + +L ++ + ++ + A Sbjct: 71 TNPLFLEEAQLSLNDGRTRFVFDDDNFIYIDEERGRVDHDKELLLEIVDNEMSKFAELEF 130 Query: 142 ---VRVDE-------FKYQMTRTGWHATEQYLIEPEKIQEM-------FPLLNMNKVLAG 184 + V + KY + R + +Q P+ + + + LL+ G Sbjct: 131 HQHLGVSDCSFFQLVMKYLLQRRQFLTNDQIRYLPQLCRYLELWHGLDWKLLSAKDTYFG 190 Query: 185 LYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARSDGTWDVETPQGS-MRANR 243 ++ S+ +A + L V S+ V G+ A+ Sbjct: 191 HQGRNAFALNYDSVVQRIAQSFPQNWLKL--SCEVKSITREPSKNVTVNCEDGTVYNADY 248 Query: 244 IVNA--------AGFWAREVGKMIGLEHPLIPV 268 ++ + + + I + PL PV Sbjct: 249 VIITVPQSVLNLSVQPEKNLRGRIEFQPPLKPV 281 >2IVE-A nrPDB Length = 478 Score = 37.5 bits (85), Expect = 0.028, Method: Composition-based stats. Identities = 13/42 (30%), Positives = 21/42 (50%) Query: 51 ETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHA 92 ++GGG G+++A+HL G V+L + L HA Sbjct: 18 NVAVVGGGISGLAVAHHLRSRGTDAVLLESSARLGGAVGTHA 59 >5UWY-A nrPDB Length = 308 Score = 37.1 bits (84), Expect = 0.031, Method: Composition-based stats. Identities = 17/72 (23%), Positives = 34/72 (47%), Gaps = 4/72 (5%) Query: 50 AETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIH 109 +T+IIG G G++ A + A++ + V ++E+ +PG + Sbjct: 5 YDTLIIGSGPAGMTAALYAARSNL-SVAIIEQGAPGG---QMNNTFDIENYPGYDHISGP 60 Query: 110 YDSIKLYEKLEE 121 ++K+YE LE+ Sbjct: 61 ELAMKMYEPLEK 72 >5MH6-A nrPDB Length = 308 Score = 37.1 bits (84), Expect = 0.032, Method: Composition-based stats. Identities = 23/172 (13%), Positives = 44/172 (25%), Gaps = 2/172 (1%) Query: 39 PLSAETQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSEL-TAGSTWHAAGLTT 97 P E ++G G +G + A GM+ V + + ST + Sbjct: 125 PRYEEPFTLAGERVCVVGLGTLGRGVVDRAAALGMEVVGVRRSGDPVDNVSTVYTPDRLH 184 Query: 98 YFHPGINLKKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVD-EFKYQMTRTGW 156 + E + + +A PV V+ + + Sbjct: 185 EAIADARFVVLATPLTDETEGMVAAPEFETMREDASLVNVARGPVVVESDLVAALDSGDI 244 Query: 157 HATEQYLIEPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARK 208 + E + E PL + VL + + + K Sbjct: 245 AGAALDVFSEEPLPEDSPLWDFEDVLITPHVSAATSKYHEDVAALIRENIEK 296 >4K2X-A nrPDB Length = 523 Score = 37.1 bits (84), Expect = 0.036, Method: Composition-based stats. Identities = 55/313 (17%), Positives = 95/313 (30%), Gaps = 67/313 (21%) Query: 49 RAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKI 108 R + VI G G G+ LA L AG + +VL +E S + Sbjct: 22 RYDVVIAGAGPTGLMLACELRLAGARTLVLERLAEPVDFS---------------KALGV 66 Query: 109 HYDSIKLYE--KLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLIEP 166 H +++L + L E + G+ P+ F + + Sbjct: 67 HARTVELLDMRGLGEGFQAEAPKLRGGNFASLGVPLDFSSFDTRHPYALF---------- 116 Query: 167 EKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARS 226 P + ++L G A + GA L+ VT+L+ + Sbjct: 117 ------VPQVRTEELLTG--------------------RALELGAELRRGHAVTALEQDA 150 Query: 227 DGTW-DVETPQGSMRAN--RIVNAAGFWAREVGKMIGLEHPLIPVQHQYVVTSTISEVKA 283 DG V P+G +V G V K++G++ P Q + Sbjct: 151 DGVTVSVTGPEGPYEVECAYLVGCDGG-GSTVRKLLGIDFP-----GQDPHMFAVIADAR 204 Query: 284 LKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNGVPPGFGKELFESDLD 343 + ELP G G++ + + V F + + Sbjct: 205 FREELP-----HGEGMGPMRPYGVMRHDLRAWFAAFPLEPDVYRATVAFFDRPYADRRAP 259 Query: 344 RIMEHIKAAMEMV 356 E ++AA+ V Sbjct: 260 VTEEDVRAALTEV 272 >2BXR-A nrPDB Length = 527 Score = 37.1 bits (84), Expect = 0.037, Method: Composition-based stats. Identities = 22/95 (23%), Positives = 41/95 (43%), Gaps = 6/95 (6%) Query: 33 EGEEKPPLSAETQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGS-TWH 91 E +EK ++ + V+IGGG G+S A L + G+ +VL + + + T Sbjct: 2 ENQEKASIAGHM-----FDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIR 56 Query: 92 AAGLTTYFHPGINLKKIHYDSIKLYEKLEEETGQV 126 + G + ++L ++L ET +V Sbjct: 57 NEHVDYVDVGGAYVGPTQNRILRLSKELGIETYKV 91 >1O5W-A nrPDB Length = 534 Score = 36.7 bits (83), Expect = 0.043, Method: Composition-based stats. Identities = 21/92 (22%), Positives = 40/92 (43%), Gaps = 6/92 (6%) Query: 36 EKPPLSAETQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGS-TWHAAG 94 EKP L+ + V+IGGG G++ A L++ + +VL + + + T Sbjct: 13 EKPNLAGHM-----FDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEH 67 Query: 95 LTTYFHPGINLKKIHYDSIKLYEKLEEETGQV 126 + G + ++L ++L ET +V Sbjct: 68 VKWVDVGGAYVGPTQNRILRLSKELGIETYKV 99 >5ZYN-B nrPDB Length = 471 Score = 36.7 bits (83), Expect = 0.043, Method: Composition-based stats. Identities = 38/218 (17%), Positives = 73/218 (33%), Gaps = 38/218 (17%) Query: 52 TVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYD 111 V+IG G G++ + L VVLL+K+ G++ A+ H D Sbjct: 7 VVVIGSGLAGLTTSNRLISKYRIPVVLLDKAASIGGNSIKASSGINGAHTDTQQNLKVMD 66 Query: 112 SIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLIEPEKIQE 171 + +L+ L++ G G L + + W TE L Sbjct: 67 TPELF--LKDTLHSAKG---RGVPSLMDKLTKESKS-----AIRWLQTEFDLK------- 109 Query: 172 MFPLLNMNKVLAGLYNPG----DGHIDP-YSLTMALAAGAR------KCGALLKYPAPVT 220 L++ L G P G + P + + AL+ + + + V Sbjct: 110 ----LDLLAQLGGHSVPRTHRSSGKLPPGFEIVQALSKKLKDISSKDSNLVQIMLNSEVV 165 Query: 221 SLKARSDGTW------DVETPQGSMRANRIVNAAGFWA 252 ++ + G D + M+++ +V +G + Sbjct: 166 DIELDNQGHVTGVVYMDENGNRKIMKSHHVVFCSGGFG 203 >1MDA-H nrPDB Length = 368 Score = 36.7 bits (83), Expect = 0.046, Method: Composition-based stats. Identities = 25/99 (25%), Positives = 36/99 (36%), Gaps = 4/99 (4%) Query: 392 WVAIGFGYGIIHAGGVGKYLSDWIL-HGEPPFDLIELDPNRYGKWTTTQYTEAKARESYG 450 WV+ G G+ +G +LS + H F L R K T Y E ++ Sbjct: 49 WVSCA-GCGVTLGHSLGAFLSLAVAGHSGSDFALASTSFARSAKGKRTDYVEVFDPVTFL 107 Query: 451 FNNIVGYPKEERFAGRPTQRVSGLYQRLESKCSMGFHAG 489 + P RF+ P RV + S C + F G Sbjct: 108 PIADIELPDAPRFSVGP--RVHIIGNCASSACLLFFLFG 144 >3RHA-A nrPDB Length = 482 Score = 36.7 bits (83), Expect = 0.050, Method: Composition-based stats. Identities = 16/40 (40%), Positives = 23/40 (57%), Gaps = 1/40 (2%) Query: 51 ETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTW 90 + VI+G G G++ A L KAG+ V +LE + G TW Sbjct: 9 DVVIVGAGPSGLTAARELKKAGL-SVAVLEARDRVGGRTW 47 >6CR0-A nrPDB Length = 440 Score = 36.3 bits (82), Expect = 0.051, Method: Composition-based stats. Identities = 7/48 (14%), Positives = 20/48 (41%) Query: 42 AETQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGST 89 + + + +++G G G+ A L+ G +++ + L + Sbjct: 1 SNAMTEKIYDAIVVGAGFSGLVAARELSAQGRSVLIIEARHRLGGRTH 48 >3ABT-A nrPDB Length = 662 Score = 36.3 bits (82), Expect = 0.053, Method: Composition-based stats. Identities = 28/127 (22%), Positives = 46/127 (36%), Gaps = 12/127 (9%) Query: 39 PLSAETQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAG------STWHA 92 PL K + +IIG G G++ A L GM DV LLE + G + Sbjct: 101 PLPT----KKTGKVIIIGSGVSGLAAARQLQSFGM-DVTLLEARDRVGGRVATFRKGNYV 155 Query: 93 AGLTTYFHPGINLKKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVD-EFKYQM 151 A L G+ + S ++ +L + + + G V+ EF + Sbjct: 156 ADLGAMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLL 215 Query: 152 TRTGWHA 158 T + + Sbjct: 216 EATSYLS 222 >4Z2R-A nrPDB Length = 592 Score = 36.3 bits (82), Expect = 0.054, Method: Composition-based stats. Identities = 39/222 (17%), Positives = 76/222 (34%), Gaps = 50/222 (22%) Query: 51 ETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHY 110 + +I+G G G A LA G++ +++ + W + PG I+ Sbjct: 14 DVLIVGAGPAGAMSATLLASLGIRSLMI---------NRWRSTS------PGPRSHIINQ 58 Query: 111 DSIKLYEKLE-EETGQVVGFHQP--GSIRLATTPVRVDEFKYQMTRTG---WHATEQYLI 164 ++++ + EE+ + + + G AT+ +EF HA E L Sbjct: 59 RTMEILRDIGLEESAKSLAVPKEYMGEHVYATSLAG-EEFGRIPAWASHPQAHA-EHELA 116 Query: 165 EPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKA 224 P + ++ ++ + P + + A GA +++ Sbjct: 117 SPSRYCDL------PQLY---FEP------------MVVSEAALRGADVRFLTEYLGHVE 155 Query: 225 RSDGTWD-----VETPQGSMRANRIVNAAGFWAREVGKMIGL 261 DG V + +RA I+ A G V + GL Sbjct: 156 DQDGVTARLLDHVSGAEYEVRAKYIIGADGAH-SLVAQNAGL 196 >2E5V-A nrPDB Length = 472 Score = 36.3 bits (82), Expect = 0.062, Method: Composition-based stats. Identities = 35/201 (17%), Positives = 67/201 (33%), Gaps = 30/201 (14%) Query: 54 IIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHY-DS 112 IIG G G+S L +AG K ++ ++ + GST A G + ++H D+ Sbjct: 4 IIGSGIAGLSAGVALRRAGKKVTLISKRID--GGSTPIAKGGVAASVGSDDSPELHAQDT 61 Query: 113 IKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLIEPEKIQEM 172 I++ + L + + G+ E +E + Sbjct: 62 IRVGDGLCD------------VKTVNYVTSEAKNVIETFESWGFEFEEDLRLEGGHTKRR 109 Query: 173 FPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARSDGTWDV 232 L ++ ++N L AR+ G + V T V Sbjct: 110 V-LHRTDETGREIFN-------------FLLKLAREEGIPIIEDRLVEIRVKDGKVTGFV 155 Query: 233 ETPQGSMR-ANRIVNAAGFWA 252 +G + +++V A G ++ Sbjct: 156 TEKRGLVEDVDKLVLATGGYS 176 >4Y4N-A nrPDB Length = 286 Score = 35.9 bits (81), Expect = 0.070, Method: Composition-based stats. Identities = 13/30 (43%), Positives = 19/30 (63%) Query: 51 ETVIIGGGCVGVSLAYHLAKAGMKDVVLLE 80 + I+GGG G++ A ++AK G K VVL Sbjct: 54 DVAIVGGGPSGLTAARYIAKEGYKVVVLER 83 >2VVL-G nrPDB Length = 495 Score = 35.9 bits (81), Expect = 0.075, Method: Composition-based stats. Identities = 20/60 (33%), Positives = 30/60 (50%), Gaps = 2/60 (3%) Query: 34 GEEKPPLSAETQWKDR-AETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHA 92 G PP + E KD + ++IGGG G++ L AG K +LLE + G +W + Sbjct: 23 GVISPPTNIEDTDKDGPWDVIVIGGGYCGLTATRDLTVAGFK-TLLLEARDRIGGRSWSS 81 >4RPJ-A nrPDB Length = 399 Score = 35.9 bits (81), Expect = 0.080, Method: Composition-based stats. Identities = 23/132 (17%), Positives = 48/132 (36%), Gaps = 13/132 (9%) Query: 49 RAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAG-------LTTYFHP 101 R + ++G G G+++A +A K V++LE+ G+ + A H Sbjct: 7 RFDLFVVGSGFFGLTIAERVATQLDKRVLVLERRPHIGGNAYSEAEPQTGIEVHKYGAHL 66 Query: 102 GINLKKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQ 161 K +D ++ + + +V H + + V +F + EQ Sbjct: 67 FHTSNKRVWDYVRQFTDFTDYRHRVFAMHNGQAYQFPMGLGLVSQF-----FGKYFTPEQ 121 Query: 162 -YLIEPEKIQEM 172 + E+ E+ Sbjct: 122 ARQLIAEQAAEI 133 >5L3D-A nrPDB Length = 852 Score = 35.6 bits (80), Expect = 0.095, Method: Composition-based stats. Identities = 28/127 (22%), Positives = 46/127 (36%), Gaps = 12/127 (9%) Query: 39 PLSAETQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAG------STWHA 92 PL K + +IIG G G++ A L GM DV LLE + G + Sbjct: 272 PLPT----KKTGKVIIIGSGVSGLAAARQLQSFGM-DVTLLEARDRVGGRVATFRKGNYV 326 Query: 93 AGLTTYFHPGINLKKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVD-EFKYQM 151 A L G+ + S ++ +L + + + G V+ EF + Sbjct: 327 ADLGAMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLL 386 Query: 152 TRTGWHA 158 T + + Sbjct: 387 EATSYLS 393 >4B1B-A nrPDB Length = 542 Score = 35.6 bits (80), Expect = 0.10, Method: Composition-based stats. Identities = 17/62 (27%), Positives = 29/62 (46%), Gaps = 1/62 (1%) Query: 50 AETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIH 109 + V+IGGG G++ A A G + V+L + + ++ T G T + K +H Sbjct: 43 YDYVVIGGGPGGMASAKEAAAHGAR-VLLFDYVKPSSQGTKWGIGGTCVNVGCVPKKLMH 101 Query: 110 YD 111 Y Sbjct: 102 YA 103 >3UP5-A nrPDB Length = 545 Score = 35.6 bits (80), Expect = 0.10, Method: Composition-based stats. Identities = 19/103 (18%), Positives = 38/103 (36%), Gaps = 9/103 (8%) Query: 51 ETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINL-KKIH 109 + V+IG G G+ A+ + +AGMK + + ++ W+ +PG L + + Sbjct: 11 DAVVIGAGVTGIYQAFLINQAGMKVLGIEAGEDVGGTWYWN-------RYPGCRLDTESY 63 Query: 110 YDSIKLYEKLEEETGQVVGF-HQPGSIRLATTPVRVDEFKYQM 151 + + E F QP +R + + Sbjct: 64 AYGYFALKGIIPEWEWSENFASQPEMLRYVNRAADAMDVRKHY 106 >4USR-A nrPDB Length = 361 Score = 35.6 bits (80), Expect = 0.11, Method: Composition-based stats. Identities = 14/52 (26%), Positives = 25/52 (48%), Gaps = 1/52 (1%) Query: 51 ETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPG 102 + ++IGGG ++ AY L + + +LL++ G+ HA F P Sbjct: 9 DVIVIGGGQAALTTAYFLRRTSL-SYLLLDEQPGPGGAWLHAWDSLRLFSPA 59 >4ZN0-A nrPDB Length = 311 Score = 35.6 bits (80), Expect = 0.11, Method: Composition-based stats. Identities = 22/110 (20%), Positives = 49/110 (44%), Gaps = 3/110 (2%) Query: 50 AETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIH 109 + +IIGGG G++ + + G+ D ++LE++E++ + P I+ ++ Sbjct: 8 YDLIIIGGGPAGLTAGIYAVRYGL-DTLILERNEISGQISMADIVENYPGFPSISGLELM 66 Query: 110 YDSIKLYEKLEEETGQ--VVGFHQPGSIRLATTPVRVDEFKYQMTRTGWH 157 +++ +T V+ G+ ++ TT E K + TG + Sbjct: 67 ERFRTHAQEVGVKTTITEVLSVRSEGTKKIITTDSGDLEAKAVIIATGAN 116 >2CUL-A nrPDB Length = 232 Score = 35.2 bits (79), Expect = 0.11, Method: Composition-based stats. Identities = 16/113 (14%), Positives = 37/113 (32%), Gaps = 3/113 (2%) Query: 50 AETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIH 109 + +I+G G G A+ LA+ G++ +L + L A + + + Sbjct: 4 YQVLIVGAGFSGAETAFWLAQKGVRVGLLTQS--LDAVMMPFLPPKPPFPPGSLLERAYD 61 Query: 110 YDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQY 162 +++ ++ +P + AT + E + W Sbjct: 62 PKDERVW-AFHARAKYLLEGLRPLHLFQATATGLLLEGNRVVGVRTWEGPPAR 113 >3JSK-A nrPDB Length = 344 Score = 35.2 bits (79), Expect = 0.12, Method: Composition-based stats. Identities = 17/97 (17%), Positives = 33/97 (34%), Gaps = 6/97 (6%) Query: 51 ETVIIGGGCVGVSLAYHLAK-AGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIH 109 + VI+G G G+S AY L+ + ++E G W G + Sbjct: 81 DIVIVGAGSCGLSAAYVLSTLRPDLRITIVEAGVAPGGGAW-LGGQLFSAMVMRKPADVF 139 Query: 110 YDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDE 146 D + + E + ++ +T +V + Sbjct: 140 LDEV----GVPYEDEGDYVVVKHAALFTSTVLSKVLQ 172 >6EZS-A nrPDB Length = 652 Score = 35.2 bits (79), Expect = 0.12, Method: Composition-based stats. Identities = 27/143 (18%), Positives = 55/143 (38%), Gaps = 20/143 (13%) Query: 635 PQARKVLQKLTSEDLSDDVFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHRREDSVAL 694 P + ++++L D + FL+ K+ + LGWE + + Sbjct: 448 PACQALMEQLGYTDYKELQGHFLRHAEDKLRKLGKRM--------LGWE---EAQHGNKV 496 Query: 695 YDA--IMNAGQEEGIDNFGTYAMNALRLEKAFRAWGLEMNCDTNPLEAGLEYF--VKLNK 750 I + EE N + + L+ A + L+M D P E G+++ + L K Sbjct: 497 SKDTVIYSWLSEEAALNCARQGFDVV-LQPAQTTY-LDMTQDYAPEEPGVDWANPLPLEK 554 Query: 751 PADFIGKQALKQIKAKGLKRRLV 773 ++ + L ++ A R+ + Sbjct: 555 AYNY---EPLAEVPADDPIRKRI 574 >6N7F-A nrPDB Length = 453 Score = 35.2 bits (79), Expect = 0.12, Method: Composition-based stats. Identities = 13/39 (33%), Positives = 21/39 (53%), Gaps = 2/39 (5%) Query: 50 AETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGS 88 + ++IGGG G++ A A G K VLL + + G+ Sbjct: 8 YDYIVIGGGSAGIASANRAAMHGAK--VLLAEGKEIGGT 44 >3LOV-A nrPDB Length = 475 Score = 35.2 bits (79), Expect = 0.13, Method: Composition-based stats. Identities = 40/173 (23%), Positives = 65/173 (37%), Gaps = 25/173 (14%) Query: 53 VIIGGGCVGVSLAYHLAKAGMK-DVVLLEKSELTAG--STWHAAGLTTYFHPGINLKKIH 109 VI+GGG G++ AY+ +A ++ LLE E G +T+ G T P + + H Sbjct: 8 VIVGGGITGLAAAYYAERAFPDLNITLLEAGERLGGKVATYREDGFTIERGPDSYVARKH 67 Query: 110 -----YDSIKLYEKLEE---------ETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTG 155 ++I L EKL +TG + + + + P +D F+ T Sbjct: 68 ILTDLIEAIGLGEKLVRNNTSQAFILDTGGLHPIPKGAVMGI---PTDLDLFRQTTLLTE 124 Query: 156 WHATEQY--LIEPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGA 206 E L+ P + P ++ L P G L L +G Sbjct: 125 EEKQEVADLLLHPSDSLRI-PEQDIP--LGEYLRPRLGDALVEKLIEPLLSGI 174 >1JWB-B nrPDB Length = 249 Score = 35.2 bits (79), Expect = 0.14, Method: Composition-based stats. Identities = 10/68 (14%), Positives = 29/68 (42%) Query: 48 DRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKK 107 + +I+G G +G + + +LA AG+ ++ LL+ ++ + + ++ Sbjct: 30 KDSRVLIVGLGGLGCAASQYLASAGVGNLTLLDFDTVSLSNLQRQTLHSDATVGQPKVES 89 Query: 108 IHYDSIKL 115 ++ Sbjct: 90 ARDALTRI 97 >3NK2-X nrPDB Length = 431 Score = 34.8 bits (78), Expect = 0.15, Method: Composition-based stats. Identities = 18/68 (26%), Positives = 30/68 (44%), Gaps = 4/68 (5%) Query: 50 AETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIH 109 + +++GGG G+ A L AG K V+LLE E G A + PG+ ++ Sbjct: 2 YDAIVVGGGFSGLKAARDLTNAG-KKVLLLEGGERLGG---RAYSRESRNVPGLRVEIGG 57 Query: 110 YDSIKLYE 117 + + Sbjct: 58 AYLHRKHH 65 >4X4J-A nrPDB Length = 507 Score = 34.8 bits (78), Expect = 0.16, Method: Composition-based stats. Identities = 21/74 (28%), Positives = 32/74 (43%), Gaps = 5/74 (6%) Query: 195 PYSLTMALAAG-ARKCGALLKYPAPVTSLKARSDGT-WDVETPQG--SMRANRIVNAAGF 250 P S T A+ A + GA ++ +T ++ DG V P G +RA +V G Sbjct: 115 PQSATEAVLEAWAGELGADIRRGHELTGVRDDGDGVAVTVRGPAGEHVLRAGWLVGCDGG 174 Query: 251 WAREVGKMIGLEHP 264 V K +G + P Sbjct: 175 -RSAVRKAVGFDFP 187 >2GMH-A nrPDB Length = 584 Score = 34.8 bits (78), Expect = 0.17, Method: Composition-based stats. Identities = 64/427 (14%), Positives = 114/427 (26%), Gaps = 82/427 (19%) Query: 48 DRAETVIIGGGCVGVSLAY---HLAKAGMKD--VVLLEKSELTAGSTWHAAGLTTYFHPG 102 + A+ VI+G G G+S A LA KD V L+EK+ T A L Sbjct: 34 EEADVVIVGAGPAGLSAATRLKQLAAQHEKDLRVCLVEKAAHIGAHTLSGACL------- 86 Query: 103 INLKKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQY 162 + +E+L + + + + TPV D F + Sbjct: 87 ---------DPRAFEELFPDWKE-----KGAPLN---TPVTEDRFGILTEKYRIPVP--- 126 Query: 163 LIEPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSL 222 + P L MN G Y GH+ + + A G + + Sbjct: 127 ---------ILPGLPMNNH--GNYVVRLGHLVSW-----MGEQAEALGVEVYPGYAAAEI 170 Query: 223 KARSDGTW-DVET----------PQGSM------RANRIVNAAGFW---AREVGKMIGLE 262 DG+ + T P+ + A + A G A+++ K L Sbjct: 171 LFHEDGSVKGIATNDVGIQKDGAPKTTFERGLELHAKVTIFAEGCHGHLAKQLYKKFDLR 230 Query: 263 HPLIPVQHQYVVTST--------ISEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYES 314 P + + P+ R G +L +G Sbjct: 231 ANCEPQTYGIGLKELWVIDEKKWKPGRVDHTVGWPLDRHTYGGSFLYHLNEGEPLLALGF 290 Query: 315 QEKMKVQDSWVTNGVPPGFGKELFESDLDRIMEHIKAAMEMVPVLKKADIINVVNGPITY 374 + Q+ +++ K + +E K +A Sbjct: 291 VVGLDYQNPYLSPFREFQRWKHH--PSIKPTLEGGKRIAY----GARALNEGGFQSIPKL 344 Query: 375 SPDILPMVGPHQGVRNYWVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRYGK 434 + ++G G N G + + + + + I L Y Sbjct: 345 TFPGGLLIGCSPGFMNVPKIKGTHTAMKSGTLAAESIFNQLTSENLQSKTIGLHVTEYED 404 Query: 435 WTTTQYT 441 + Sbjct: 405 NLKNSWV 411 >4HA6-A nrPDB Length = 508 Score = 34.4 bits (77), Expect = 0.20, Method: Composition-based stats. Identities = 37/216 (17%), Positives = 62/216 (28%), Gaps = 28/216 (12%) Query: 51 ETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKS----ELTAGSTWHAAGLTTYFHPG--IN 104 + VI+GGG G LA L++ V+L+E + + L + Sbjct: 3 DIVIVGGGSAGSLLAARLSEDPDSRVLLIEAGEEPTDPDIWNPAAWPALQGRSYDWDYRT 62 Query: 105 LKKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTG--WHATEQY 162 + + G H G +R +F+ + +G + Sbjct: 63 EAQAGTAGRAHHWARGRLIGGSSCLHAMGYMR-----GHPSDFQAWVDASGDRRWGWD-E 116 Query: 163 LIEPEKIQEMFPLLNMNKVLAG----LYNPGDGHIDPYSLTMALAAGARKCGALLKYPAP 218 L+ + E PL G ++ P D + L A G Sbjct: 117 LLPVFQAIEDHPLGGDGIHGKGGPLPIHLPAD---EVSPLARAFIEAGASLGLPRLEGH- 172 Query: 219 VTSLKARSDGTWDVETPQGSMRANRIVNAAGFWARE 254 S V ++R R V AA W + Sbjct: 173 ------NSGEMIGVTPNSLNIRDGRRVTAADAWLTK 202 >5TUK-A nrPDB Length = 408 Score = 34.4 bits (77), Expect = 0.23, Method: Composition-based stats. Identities = 16/101 (15%), Positives = 31/101 (30%), Gaps = 5/101 (4%) Query: 52 TVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYD 111 ++IG G G ++ Y L + G +++ + L G HA + I+ Sbjct: 28 ILVIGAGIAGPAVCYWLRRFGFSPILVERCANLRKG--GHAVDIRGVAIDLAKSMGIYKK 85 Query: 112 SIKLYEKLEEETGQVVG---FHQPGSIRLATTPVRVDEFKY 149 + ++E H+ R E Sbjct: 86 ICNMRTQVELGRYVDAEGNILHEEKGERFGFREGDDIEILR 126 >2Q7V-A nrPDB Length = 325 Score = 34.0 bits (76), Expect = 0.25, Method: Composition-based stats. Identities = 14/54 (25%), Positives = 22/54 (40%), Gaps = 1/54 (1%) Query: 50 AETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGI 103 + VIIGGG G++ A + +A + ++LEK W P Sbjct: 9 YDVVIIGGGPAGLTAAIYTGRAQL-STLILEKGMPGGQIAWSEEVENFPGFPEP 61 >4NTC-A nrPDB Length = 335 Score = 34.0 bits (76), Expect = 0.26, Method: Composition-based stats. Identities = 17/116 (14%), Positives = 32/116 (27%), Gaps = 7/116 (6%) Query: 51 ETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHY 110 + +IIG G G+S A LA+ + V+ + T H + + H + Sbjct: 16 DVLIIGAGPAGLSTATGLARQ-LHTAVVFDSGVYRNAKTQHMHNVLGWDHRNPAELRAAG 74 Query: 111 DSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLIEP 166 + L + F + W+ + L Sbjct: 75 RA-----DLTTR-YSTIQFQNSTIEAIRQVETNQLFEARDNEGHSWYGRKVVLATG 124 >2WOV-A nrPDB Length = 495 Score = 34.0 bits (76), Expect = 0.28, Method: Composition-based stats. Identities = 36/204 (17%), Positives = 68/204 (33%), Gaps = 43/204 (21%) Query: 48 DRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKK 107 + V+IG G G+ ++ A K V +++ + + G ++AA T + G KK Sbjct: 6 KAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVD-VQTSHGPPFYAALGGTCVNVGCVPKK 64 Query: 108 IHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLIEPE 167 + + + L E G F D + A + Sbjct: 65 LMVTGAQYMDHLRESAGFGWEF---------------DGSSVKANWKKLIAAKNE----- 104 Query: 168 KIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARSD 227 +L++NK G++N +G L V ++ +D Sbjct: 105 ------AVLDINKSYEGMFNDTEGLDF--FLGWGSLESKN-----------VVVVRETAD 145 Query: 228 GTWDVETPQGSMRANRIVNAAGFW 251 V+ ++A+ I+ A G W Sbjct: 146 PKSAVKE---RLQADHILLATGSW 166 >3VH2-A nrPDB Length = 616 Score = 34.0 bits (76), Expect = 0.32, Method: Composition-based stats. Identities = 18/122 (14%), Positives = 45/122 (36%), Gaps = 2/122 (1%) Query: 48 DRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKK 107 + +++G G +G ++ L G++ + ++ ++ + A L + G + Sbjct: 326 KNTKVLLLGAGTLGCYVSRALIAWGVRKITFVDNGTVSYSNPVRQA-LYNFEDCGKPKAE 384 Query: 108 IHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLIEPE 167 + S+K L + TG + G +L + +F H L++ Sbjct: 385 LAAASLKRIFPLMDATGVKLSIPMIGH-KLVNEEAQHKDFDRLRALIKEHDIIFLLVDSR 443 Query: 168 KI 169 + Sbjct: 444 ES 445 >3T7E-A nrPDB Length = 344 Score = 34.0 bits (76), Expect = 0.32, Method: Composition-based stats. Identities = 18/122 (14%), Positives = 45/122 (36%), Gaps = 2/122 (1%) Query: 48 DRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKK 107 + +++G G +G ++ L G++ + ++ ++ + A L + G + Sbjct: 37 KNTKVLLLGAGTLGCYVSRALIAWGVRKITFVDNGTVSYSNPVRQA-LYNFEDCGKPKAE 95 Query: 108 IHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLIEPE 167 + S+K L + TG + G +L + +F H L++ Sbjct: 96 LAAASLKRIFPLMDATGVKLSIPMIGH-KLVNEEAQHKDFDRLRALIKEHDIIFLLVDSR 154 Query: 168 KI 169 + Sbjct: 155 ES 156 >4GCM-A nrPDB Length = 312 Score = 34.0 bits (76), Expect = 0.32, Method: Composition-based stats. Identities = 16/68 (23%), Positives = 29/68 (42%), Gaps = 4/68 (5%) Query: 50 AETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIH 109 + IIG G G++ A + ++A +K V++E+ A PG + Sbjct: 7 FDIAIIGAGPAGMTAAVYASRANLK-TVMIERGIPGG---QMANTEEVENFPGFEMITGP 62 Query: 110 YDSIKLYE 117 S K++E Sbjct: 63 DLSTKMFE 70 >4Z25-A nrPDB Length = 652 Score = 33.6 bits (75), Expect = 0.36, Method: Composition-based stats. Identities = 13/32 (40%), Positives = 19/32 (59%) Query: 51 ETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKS 82 + VIIG G G LA++LA+ ++LLE Sbjct: 8 DIVIIGAGAAGSLLAHYLARFSNMKIILLEAG 39 >2HQM-A nrPDB Length = 479 Score = 33.6 bits (75), Expect = 0.41, Method: Composition-based stats. Identities = 41/212 (19%), Positives = 73/212 (34%), Gaps = 21/212 (9%) Query: 48 DRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAG--STWHAAGLTTYFHPGINL 105 + ++IGGG GV+ A A G K +L+E L + ++ + Sbjct: 10 KHYDYLVIGGGSGGVASARRAASYGAK-TLLVEAKALGGTCVNVGCVPKKVMWYASDLAT 68 Query: 106 KKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLIE 165 + H + LY+ L + + + + D + +++ + Q +E Sbjct: 69 RVSHANEYGLYQNLPLDKEHL-------TFNWPEFKQKRDAYVHRL-----NGIYQKNLE 116 Query: 166 PEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKAR 225 EK+ +F NK D + YS L A A+ P L Sbjct: 117 KEKVDVVFGWARFNKDGNVEVQKRDNTTEVYSANHILV--ATGGKAIFPENIPGFELGTD 174 Query: 226 SDGTWDVETPQGSMRANRIVNAAGFWAREVGK 257 SDG + +E +V AG+ E+ Sbjct: 175 SDGFFRLE----EQPKKVVVVGAGYIGIELAG 202 >5TUM-A nrPDB Length = 410 Score = 33.2 bits (74), Expect = 0.46, Method: Composition-based stats. Identities = 29/172 (16%), Positives = 56/172 (32%), Gaps = 21/172 (12%) Query: 48 DRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTW--------HAAGLTTYF 99 + ++IG G G ++ Y L + G V++ + + + G H A + Sbjct: 24 KNIKILVIGAGVAGPAVCYWLRRFGFSPVLIEKYASIRKGGQALDVRGIATHIAREMGIY 83 Query: 100 HPGINL-----KKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRT 154 + + DS L EE G+ GF Q + + + E + Sbjct: 84 DQICEMRTRIERGRFVDSSGKV--LHEEQGEKFGFRQDDEVEI--LRGDLVEILMKTIAD 139 Query: 155 GWHATEQYLIEPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGA 206 Q +I E+ + ++ M+ G D I + A+ Sbjct: 140 VPCYFNQSIISIEQNADNVTVIFMD----GRIEQYDLVIAADGIHSAIRRMI 187 >4JNQ-A nrPDB Length = 345 Score = 33.2 bits (74), Expect = 0.48, Method: Composition-based stats. Identities = 30/228 (13%), Positives = 67/228 (29%), Gaps = 30/228 (13%) Query: 47 KDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLK 106 + A ++IG G G + A + A+A +K VV+ G + Y ++ Sbjct: 24 QRHAPVIVIGSGPAGYTAAIYAARAMLKPVVI--AGLQQGGQLMITTDVENYPGYAEPVQ 81 Query: 107 KIH--YDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLI 164 + E + + + + V F+ + + + LI Sbjct: 82 GPWMMEQMARQAENVGAQIVHDI---------ITEVETTVRPFRLKGDSGTIYTCDA-LI 131 Query: 165 EPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTS--L 222 Q + L + G G + + + + V Sbjct: 132 IATGAQAKWLGLESEQTFMG------GGVSACATCDGFFYRGKDVVVVGGGNTAVEEALY 185 Query: 223 KARSDGTWDVETPQGSMRANRIV--------NAAGFWAREVGKMIGLE 262 + + + + RA +I+ N + W + +++G E Sbjct: 186 LSHIAKSVTIVHRRDGFRAEKIMQDRLLSRENVSVVWNSVIDEILGTE 233 >5EQD-A nrPDB Length = 400 Score = 33.2 bits (74), Expect = 0.48, Method: Composition-based stats. Identities = 19/131 (14%), Positives = 43/131 (32%), Gaps = 11/131 (8%) Query: 49 RAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAG-------LTTYFHP 101 + ++G G G+++A A K V+++E+ G+ + H Sbjct: 4 NFDLFVVGSGFFGLTIAERAATQLGKRVLVIERRPHIGGNAYSEPEPETGIEVHKYGAHL 63 Query: 102 GINLKKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQ 161 K +D ++ + +V H + + V +F + E Sbjct: 64 FHTSNKRVWDYVRQFTDFTGYQHRVFAMHNGQAYQFPMGLGLVSQFFGRYFSPD----EA 119 Query: 162 YLIEPEKIQEM 172 + E+ E+ Sbjct: 120 RALIAEQASEI 130 >1UXJ-A nrPDB Length = 309 Score = 33.2 bits (74), Expect = 0.49, Method: Composition-based stats. Identities = 14/32 (43%), Positives = 20/32 (62%) Query: 49 RAETVIIGGGCVGVSLAYHLAKAGMKDVVLLE 80 R + IIG G VG + A+ LA + D+VLL+ Sbjct: 2 RKKISIIGAGFVGSTTAHWLAAKELGDIVLLD 33 >4MOP-A nrPDB Length = 633 Score = 32.9 bits (73), Expect = 0.57, Method: Composition-based stats. Identities = 16/54 (29%), Positives = 25/54 (46%), Gaps = 5/54 (9%) Query: 38 PPLSAE----TQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAG 87 PPL + + VI+G G +G + A L AG K V + + E+ +G Sbjct: 31 PPLPGPDKKVPGMDIKYDVVIVGSGPIGCTYARELVGAGYK-VAMFDIGEIDSG 83 >1FEC-A nrPDB Length = 490 Score = 32.9 bits (73), Expect = 0.61, Method: Composition-based stats. Identities = 34/209 (16%), Positives = 61/209 (29%), Gaps = 43/209 (20%) Query: 48 DRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKK 107 + V+IG G G+ ++ A K V +++ + G +AA T + G KK Sbjct: 2 RAYDLVVIGAGSGGLEAGWNAASLHKKRVAVIDLQKH-HGPPHYAALGGTCVNVGCVPKK 60 Query: 108 IHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLIEPE 167 + + + E G E + R W A Sbjct: 61 LMVTGANYMDTIRESAGF------------------GWELDRESVRPNWKALIA------ 96 Query: 168 KIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARSD 227 + +N G++ +G A L++ A + Sbjct: 97 AKNKAVSGIN--DSYEGMFADTEGLTFH----QGFGALQDNHTVLVRESA-------DPN 143 Query: 228 GTWDVETPQGSMRANRIVNAAGFWAREVG 256 +ET I+ A G W + +G Sbjct: 144 SAV-LETLDTEY----ILLATGSWPQHLG 167 >4IA5-A nrPDB Length = 591 Score = 32.9 bits (73), Expect = 0.64, Method: Composition-based stats. Identities = 16/85 (18%), Positives = 30/85 (35%), Gaps = 5/85 (5%) Query: 41 SAETQWKDRAETVIIGGGCVGVSLAYHLAKAGM---KDVVLLEKSELTAGSTWHA--AGL 95 + D+ IIG G G+S A L + +++ +LE+ + GS A Sbjct: 14 PKKPAGVDKKSAYIIGSGLAGLSTAVFLVRDAQMKGENIHILEELPVAGGSLDGADRPNA 73 Query: 96 TTYFHPGINLKKIHYDSIKLYEKLE 120 G ++ +Y + Sbjct: 74 GFVVRGGREMENHFECLWDMYRSIP 98 >1V59-A nrPDB Length = 478 Score = 32.9 bits (73), Expect = 0.64, Method: Composition-based stats. Identities = 21/107 (19%), Positives = 37/107 (34%), Gaps = 9/107 (8%) Query: 48 DRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKK 107 + VIIGGG G A A+ G + ++ +L T I K Sbjct: 4 KSHDVVIIGGGPAGYVAAIKAAQLGFNTACVEKRGKLGG---------TCLNVGCIPSKA 54 Query: 108 IHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRT 154 + +S ++ E + + + I +A D+ Q+T Sbjct: 55 LLNNSHLFHQMHTEAQKRGIDVNGDIKINVANFQKAKDDAVKQLTGG 101 >5Z70-A nrPDB Length = 605 Score = 32.9 bits (73), Expect = 0.66, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 29/72 (40%), Gaps = 5/72 (6%) Query: 54 IIGGGCVGVSLAYHLAKAGM---KDVVLLEKSELTAGS--TWHAAGLTTYFHPGINLKKI 108 IIG G G++ A++L + G +D+ +L+ GS A G + Sbjct: 9 IIGSGIAGLASAFYLIRDGRMKGQDITILDAVGTPGGSLDGSGNAEDGYLIRGGREMNWN 68 Query: 109 HYDSIKLYEKLE 120 + L++ + Sbjct: 69 YDHFWDLFQDIP 80 >4OEN-A nrPDB Length = 223 Score = 32.9 bits (73), Expect = 0.69, Method: Composition-based stats. Identities = 13/57 (22%), Positives = 26/57 (45%) Query: 603 DLRWIEEEAVKGGYDVEIKNITDELGVLGVAGPQARKVLQKLTSEDLSDDVFKFLQT 659 D+ I+ A G+++EI N + + V QA ++ ++ D F F ++ Sbjct: 29 DMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGMSVTDARKATFDFSES 85 >4K22-A nrPDB Length = 365 Score = 32.9 bits (73), Expect = 0.69, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 33/73 (45%), Gaps = 9/73 (12%) Query: 48 DRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKK 107 + I+GGG VG+++A L +G++ VL ++ + L P + + Sbjct: 2 QSVDVAIVGGGMVGLAVACGLQGSGLRVAVLEQRVQEP---------LAANAPPQLRVSA 52 Query: 108 IHYDSIKLYEKLE 120 I+ S KL +L Sbjct: 53 INAASEKLLTRLG 65 >3G5Q-A nrPDB Length = 443 Score = 32.5 bits (72), Expect = 0.75, Method: Composition-based stats. Identities = 54/380 (14%), Positives = 109/380 (28%), Gaps = 56/380 (14%) Query: 54 IIGGGCVGVSLAYHLAKAGMKDVVLLE---KSELTAGSTWHAAGLTTYF----HPGINLK 106 ++G G G A+ L + G+ V L E K A T A + N K Sbjct: 6 VVGAGLAGSEAAWTLLRLGV-PVRLFEMRPKRMTPAHGTDRFAEIVCSNSLGGEGETNAK 64 Query: 107 KIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLIEP 166 + ++ L E + G++ + +EF +T ++ Sbjct: 65 GLLQAEMRRAGSLVMEAADLARVPAGGALAV-----DREEFSGYITERLTGHPLLEVVR- 118 Query: 167 EKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARS 226 E+++E+ P + + G + +L AL + G S Sbjct: 119 EEVREIPPGITVL---------ATGPLTSEALAEALKR---RFGDHFLAYYDAASPIVLY 166 Query: 227 DGTWDVETPQGSMRANRIVNAAGFWAREVGKMIGLEHPLIPVQHQYVVTSTISEVKALKR 286 + + RA R +A + L P+ +++ + + + Sbjct: 167 ESIDLTKC----FRAGRYGQSADY----------LNCPMTEEEYRRFHQALLEAQRHTPH 212 Query: 287 ELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNGVPPGFGKELFESDLDRIM 346 + L E + + K T P + E R+ Sbjct: 213 DWEKLEFFEACVPVEELARRGYQTLLFGPMKPVGLVDPRTGKEPFAVVQLRQEDKAGRMW 272 Query: 347 EHI-----------KAAMEMVPVLKKADIINVVNGPITYSPDILPMVGPHQGVR---NYW 392 + K ++M+P L+ A+I+ + ++G R + Sbjct: 273 SLVGFQTGLKWPEQKRLIQMIPGLENAEIVRYGVMHRNTYLNAPRLLGETLEFREAEGLY 332 Query: 393 VAIGFG--YGIIHAGGVGKY 410 A G + + G Sbjct: 333 AAGVLAGVEGYLESAATGFL 352 >4N9X-A nrPDB Length = 411 Score = 32.5 bits (72), Expect = 0.75, Method: Composition-based stats. Identities = 17/72 (23%), Positives = 30/72 (41%), Gaps = 3/72 (4%) Query: 48 DRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKK 107 + VI GGG VG++LA L +G++ VL +++ A + + Sbjct: 2 QSFDVVIAGGGMVGLALACGLQGSGLRIAVLEKQAAEPQTLGKGHALRVSAINAASE--- 58 Query: 108 IHYDSIKLYEKL 119 I ++E L Sbjct: 59 CLLRHIGVWENL 70 >1CSN-A nrPDB Length = 298 Score = 32.5 bits (72), Expect = 0.75, Method: Composition-based stats. Identities = 11/44 (25%), Positives = 23/44 (52%) Query: 37 KPPLSAETQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLE 80 +P S Q +D T + GC G+ Y+ + G+ +V++++ Sbjct: 43 EPRRSDAPQLRDEYRTYKLLAGCTGIPNVYYFGQEGLHNVLVID 86 >4OVI-A nrPDB Length = 542 Score = 32.5 bits (72), Expect = 0.77, Method: Composition-based stats. Identities = 8/42 (19%), Positives = 18/42 (42%) Query: 45 QWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTA 86 Q + + +++G G G+ Y L + G V+ ++ Sbjct: 12 QPPEEVDVLVVGAGFSGLYALYRLRELGRSVHVIETAGDVGG 53 >3WSV-A nrPDB Length = 322 Score = 32.5 bits (72), Expect = 0.80, Method: Composition-based stats. Identities = 12/33 (36%), Positives = 20/33 (60%) Query: 47 KDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLL 79 K + VI+G G VG S+AY + G+ + ++L Sbjct: 3 KTSRKVVIVGTGFVGTSIAYAMINQGVANELVL 35 >1I8T-A nrPDB Length = 367 Score = 32.5 bits (72), Expect = 0.80, Method: Composition-based stats. Identities = 13/51 (25%), Positives = 21/51 (41%), Gaps = 1/51 (1%) Query: 50 AETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFH 100 + +I+G G G A L K K V+++EK G+ + H Sbjct: 2 YDYIIVGSGLFGAVCANELKKLN-KKVLVIEKRNHIGGNAYTEDCEGIQIH 51 >6C6P-A nrPDB Length = 458 Score = 32.5 bits (72), Expect = 0.83, Method: Composition-based stats. Identities = 12/37 (32%), Positives = 21/37 (56%) Query: 44 TQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLE 80 T ++ E +I+G G +G +LA L++ G K V+ Sbjct: 2 TSSQNDPEVIIVGAGVLGSALAAVLSRDGRKVTVIER 38 >4IVM-B nrPDB Length = 483 Score = 32.5 bits (72), Expect = 0.85, Method: Composition-based stats. Identities = 25/152 (16%), Positives = 46/152 (30%), Gaps = 19/152 (12%) Query: 98 YFHPGINLKKIHYDS--IKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTG 155 G + + DS ++ E F S+ A R + Sbjct: 157 QRRLGPEVASLAMDSLCRGVFAGNSRELSIRSCFP---SLFQAEQTHRSILLGLLLGAGR 213 Query: 156 WHATEQYLIEPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKY 215 + LI + + E + ++ G L AL G + Sbjct: 214 TPQPDSALIR-QALAERW----------SQWSLRGGL---EMLPQALETHLTSRGVSVLR 259 Query: 216 PAPVTSLKARSDGTWDVETPQGSMRANRIVNA 247 PV L +++G W V S+ A+ +++A Sbjct: 260 GQPVCGLSLQAEGRWKVSLRDSSLEADHVISA 291 Score = 31.7 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 16/37 (43%), Positives = 24/37 (64%), Gaps = 1/37 (2%) Query: 52 TVIIGGGCVGVSLAYHLAKAGM-KDVVLLEKSELTAG 87 V++GGG G++ +YHL++A VVL+E SE G Sbjct: 11 VVVLGGGISGLAASYHLSRAPCPPKVVLVESSERLGG 47 >2NVK-X nrPDB Length = 488 Score = 32.5 bits (72), Expect = 0.85, Method: Composition-based stats. Identities = 13/47 (27%), Positives = 20/47 (42%), Gaps = 1/47 (2%) Query: 50 AETVIIGGGCVGVSLAYHLAKAGMKDVVL-LEKSELTAGSTWHAAGL 95 + ++IGGG G++ A G + L K T G+ W G Sbjct: 10 YDLIVIGGGSAGLACAKEAVLNGARVACLDFVKPTPTLGTKWGVGGT 56 >4NEW-A nrPDB Length = 492 Score = 32.1 bits (71), Expect = 0.96, Method: Composition-based stats. Identities = 34/202 (16%), Positives = 65/202 (32%), Gaps = 43/202 (21%) Query: 50 AETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIH 109 + V+IG G G+ A++ A K V +++ ++ G + +A T + G KK+ Sbjct: 6 FDLVVIGAGSGGLEAAWNAATLYKKRVAVID-VQMVHGPPFFSALGGTCVNVGCVPKKLM 64 Query: 110 YDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLIEPEKI 169 + E L E G F + + A + Sbjct: 65 VTGAQYMEHLRESAGFGWEFDRTTL---------------RAEWKNLIAVKDE------- 102 Query: 170 QEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPVTSLKARSDGT 229 +LN+NK ++ +G L V +++ +D Sbjct: 103 ----AVLNINKSYDEMFRDTEGLEF--FLGWGSLESKN-----------VVNVRESADPA 145 Query: 230 WDVETPQGSMRANRIVNAAGFW 251 V+ + I+ A+G W Sbjct: 146 SAVKE---RLETEHILLASGSW 164 >2A9F-A nrPDB Length = 398 Score = 32.1 bits (71), Expect = 1.0, Method: Composition-based stats. Identities = 20/89 (22%), Positives = 29/89 (32%), Gaps = 3/89 (3%) Query: 48 DRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKK 107 D V+ GGG G+S+ L AG V +++K A H I Sbjct: 187 DEVSIVVNGGGSAGLSITRKLLAAGATKVTVVDKF---GIINEQEAAQLAPHHLDIAKVT 243 Query: 108 IHYDSIKLYEKLEEETGQVVGFHQPGSIR 136 E E +G PG ++ Sbjct: 244 NREFKSGTLEDALEGADIFIGVSAPGVLK 272 >4YNU-A nrPDB Length = 571 Score = 32.1 bits (71), Expect = 1.1, Method: Composition-based stats. Identities = 10/34 (29%), Positives = 19/34 (55%) Query: 49 RAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKS 82 + +++GGG G+ +A L++ V+LLE Sbjct: 5 TYDYIVVGGGTSGLVVANRLSENPDVSVLLLEAG 38 >4LBU-A nrPDB Length = 388 Score = 32.1 bits (71), Expect = 1.1, Method: Composition-based stats. Identities = 32/232 (13%), Positives = 66/232 (28%), Gaps = 44/232 (18%) Query: 476 QRLESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFEPVGSEYKQVMQRVAVTDLS 535 +R+ + GW++P G S + + + + + LS Sbjct: 83 ERIAKLGGLHSFMGWDRPILTDSGGYQVMSLSSLTKQSEEGVTFKSHLDGSRHM----LS 138 Query: 536 PFGKFNIKGQDSIRLLDHLFANVIPKVGFTNISHMLTPKGRVYAELTVSHQSPGEFLLIT 595 P I HL + I + E T +P Sbjct: 139 PERSIEI---------QHLLGSDIV---------------MAFDECTPYPATPSR----- 169 Query: 596 GSGSELHDLRWIEEEAVKGGYDVEIKNITDELGVLGVAGPQARKVLQKLTSEDLSDDVFK 655 + S +RW + K + + G+ + L++ +++ L++ F Sbjct: 170 AASSMERSMRWAKRSRDAFDSR---KEQAENAALFGIQQGSVFENLRQQSADALAEIGFD 226 Query: 656 FLQTKSLKVSNIPVTAIRISYTGELGWELYHRREDSVALYDAIMNAGQEEGI 707 L V R+ L + + +D +M G+ + I Sbjct: 227 GYAVGGLAVGEGQDEMFRV-----LDFSVPMLPDDKPHY---LMGVGKPDDI 270 >3DL2-A nrPDB Length = 303 Score = 32.1 bits (71), Expect = 1.1, Method: Composition-based stats. Identities = 26/136 (19%), Positives = 54/136 (39%), Gaps = 7/136 (5%) Query: 37 KPPLSAETQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLT 96 A + K + ++GGG +G++ ++ G+ D ++L +L+ G+ L Sbjct: 2 SSKSWANHENKTVNKITVVGGGELGIACTLAISAKGIADRLVL--LDLSEGTKGATMDLE 59 Query: 97 TYFHPGINLKKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGW 156 + P + + K S + K+ T +G Q L VD F+ + G Sbjct: 60 IFNLPNVEISK--DLSASAHSKVVIFTVNSLGSSQS---YLDVVQSNVDMFRALVPALGH 114 Query: 157 HATEQYLIEPEKIQEM 172 ++ L+ + E+ Sbjct: 115 YSQHSVLLVASQPVEI 130 >5BR7-A nrPDB Length = 393 Score = 32.1 bits (71), Expect = 1.2, Method: Composition-based stats. Identities = 22/104 (21%), Positives = 40/104 (38%), Gaps = 28/104 (26%) Query: 50 AETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIH 109 + +++G G G+++A A K V+++EK G+ Sbjct: 4 FDLIVVGSGLFGLTVAERAASQLGKKVLIVEKRSHLGGNA-------------------- 43 Query: 110 YDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTR 153 Y + E ETG + H+ G+ T+ RV ++ Q T Sbjct: 44 ------YSEAEPETG--IEIHKYGAHLFHTSNKRVWDYVNQFTA 79 >4UDQ-A nrPDB Length = 531 Score = 32.1 bits (71), Expect = 1.2, Method: Composition-based stats. Identities = 12/33 (36%), Positives = 17/33 (51%) Query: 50 AETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKS 82 + VI+GGG G LA L+ V+L+E Sbjct: 6 FDYVIVGGGTAGSVLANRLSARPENRVLLIEAG 38 >5CEE-A nrPDB Length = 413 Score = 31.7 bits (70), Expect = 1.6, Method: Composition-based stats. Identities = 18/87 (20%), Positives = 36/87 (41%), Gaps = 8/87 (9%) Query: 51 ETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIH- 109 + VI G G G+++A L + +VVL++K + G+ P L ++ Sbjct: 209 QVVINGAGSAGMAIAKMLLLLKVNNVVLVDK------TGTLYKGVANLNEPQKKLVEVTN 262 Query: 110 -YDSIKLYEKLEEETGQVVGFHQPGSI 135 Y +++ + +G PG + Sbjct: 263 KYQEKGTLKEVLKGKDIFIGVSAPGIV 289 >4MO2-B nrPDB Length = 368 Score = 31.7 bits (70), Expect = 1.6, Method: Composition-based stats. Identities = 10/39 (25%), Positives = 19/39 (48%), Gaps = 1/39 (2%) Query: 50 AETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGS 88 + +I+G G G AY + G +++E+ E G+ Sbjct: 2 YDYLIVGSGLFGSIFAYEATEKGYT-CLVVEQREHIGGN 39 >3Q6J-A nrPDB Length = 523 Score = 31.3 bits (69), Expect = 1.7, Method: Composition-based stats. Identities = 17/96 (17%), Positives = 38/96 (39%), Gaps = 2/96 (2%) Query: 43 ETQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPG 102 E ++ + + IGGG G + +L G + +++++ GS H A + + Sbjct: 38 ENDPRE-YDAIFIGGGAAGRFGSAYLRAMGGRQ-LIVDRWPFLGGSCPHNACVPHHLFSD 95 Query: 103 INLKKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLA 138 + + + + T +VVG + + A Sbjct: 96 CAAELMLARTFSGQYWFPDMTEKVVGIKEVVDLFRA 131 >2ZBW-A nrPDB Length = 335 Score = 31.3 bits (69), Expect = 1.7, Method: Composition-based stats. Identities = 19/124 (15%), Positives = 35/124 (28%), Gaps = 11/124 (8%) Query: 48 DRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKK 107 D + +I+G G G+ +++ G+ + E T Y G Sbjct: 4 DHTDVLIVGAGPTGLFAGFYVGMRGLSFRFVDPLPEPGGQLTALYPEKYIYDVAGFPKVY 63 Query: 108 IHYDSIKLYEK---------LEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHA 158 L E+ L E + + ++ T+ K + G A Sbjct: 64 AKDLVKGLVEQVAPFNPVYSLGERAETLE--REGDLFKVTTSQGNAYTAKAVIIAAGVGA 121 Query: 159 TEQY 162 E Sbjct: 122 FEPR 125 >1PS9-A nrPDB Length = 671 Score = 31.3 bits (69), Expect = 1.7, Method: Composition-based stats. Identities = 21/98 (21%), Positives = 39/98 (39%), Gaps = 12/98 (12%) Query: 35 EEKPPLSAETQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAG 94 E K P+ Q K+ A ++G G G++ A + A G + + SE+ Sbjct: 362 ETKMPILPAVQKKNLA---VVGAGPAGLAFAINAAARGHQVTLFDAHSEIGGQF------ 412 Query: 95 LTTYFHPGINLKKIHYDSIKLYEKLEEETGQVVGFHQP 132 PG Y++++ Y ++ E TG + + Sbjct: 413 NIAKQIPGKEE---FYETLRYYRRMIEVTGVTLKLNHT 447 >2X3N-A nrPDB Length = 399 Score = 31.3 bits (69), Expect = 1.8, Method: Composition-based stats. Identities = 25/126 (19%), Positives = 44/126 (34%), Gaps = 12/126 (9%) Query: 51 ETVIIGGGCVGVSLAYHLAKAGMKDVVLL---EKSELTAGSTWHAAGLTTYFHPGINLKK 107 + +I G G G LAY L + G + VV+ + + AG+ G+ L + Sbjct: 8 DVLINGCGIGGAMLAYLLGRQGHRVVVVEQARRERAINGADLLKPAGIRVVEAAGL-LAE 66 Query: 108 IHYDSIKLYEKLEEETGQVVGFHQPGSIR-LATTPVRVDEFKYQMTRTGWHATEQYLIEP 166 + ++ +LE +H +R + V + M I+ Sbjct: 67 VTRRGGRVRHELE-------VYHDGELLRYFNYSSVDARGYFILMPCESLRRLVLEKIDG 119 Query: 167 EKIQEM 172 E EM Sbjct: 120 EATVEM 125 >5TUF-A nrPDB Length = 409 Score = 31.3 bits (69), Expect = 1.9, Method: Composition-based stats. Identities = 21/95 (22%), Positives = 37/95 (38%), Gaps = 11/95 (11%) Query: 48 DRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTW--------HAAGLTTYF 99 + ++IG G G ++AY L + G V++ + + + G H A + Sbjct: 24 KHIKILVIGVGVAGPAVAYWLKRFGFSPVLIEKSAAVRKGGQALDIRGIATHIAKEMGIY 83 Query: 100 HPGINLKKIHYDSIKLYEK---LEEETGQVVGFHQ 131 N++ + K L EE G+ GF Q Sbjct: 84 DQICNMRTQIKCGRYVDVKGNVLHEEQGETFGFRQ 118 >2QA1-A nrPDB Length = 500 Score = 31.3 bits (69), Expect = 2.0, Method: Composition-based stats. Identities = 18/62 (29%), Positives = 27/62 (43%), Gaps = 4/62 (6%) Query: 206 ARKCGALLKYPAPVTSLKARSDGTW-DVETPQG--SMRANRIVNAAGFWAREVGKMIGLE 262 A GA ++ V SL G +V P+G ++RA +V G + V K G + Sbjct: 116 ATGLGADIRRGHEVLSLTDDGAGVTVEVRGPEGKHTLRAAYLVGCDGGRSS-VRKAAGFD 174 Query: 263 HP 264 P Sbjct: 175 FP 176 >4AP1-A nrPDB Length = 549 Score = 31.3 bits (69), Expect = 2.0, Method: Composition-based stats. Identities = 15/104 (14%), Positives = 32/104 (30%), Gaps = 7/104 (6%) Query: 49 RAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKI 108 + V++G G G+ + G+ S + W+ Y +++ I Sbjct: 21 SYDVVVVGAGIAGLYAIHRFRSQGLTVRAFEAASGVGGVWYWN-----RYPGARCDVESI 75 Query: 109 HYDSIKLYEKLEEETG-QVVGFHQPGSIRLATTPVRVDEFKYQM 151 S +LE+E QP + + + + Sbjct: 76 -DYSYSFSPELEQEWNWSEKYATQPEILAYLEHVADRFDLRRDI 118 >5EVY-X nrPDB Length = 438 Score = 30.9 bits (68), Expect = 2.2, Method: Composition-based stats. Identities = 64/456 (14%), Positives = 128/456 (28%), Gaps = 71/456 (15%) Query: 47 KDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGIN-- 104 K +IGGG G +LA L+K+ +V L E + G I Sbjct: 20 KSPLRVAVIGGGIAGTALALGLSKSSHVNVKLFETA-PAFGEIGAGVSFGVNAVEAIQRL 78 Query: 105 -----LKKIHYDSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHAT 159 K + + ++ + E H + P ++ Sbjct: 79 GIGELYKSVADSTPAPWQDIWFEWRHA---HDASLVGATVAPGIGQSSIHRADF--IDML 133 Query: 160 EQYLIEPEKIQEMFPLLNMNKVLAGLYNPGDGHIDPYSLTMALAAGARKCGALLKYPAPV 219 E+ L + N DG + +A G +K Sbjct: 134 EKRLPAGIASLGKHVVDYTENAEGVTLNFADGSTYTADVAIA------ADG--IKSSMRN 185 Query: 220 TSLKARSDGTWDVETPQGSMRANRIVNAA---GFWAREVGKMIGLEHPLIPVQHQYVVTS 276 T L+A + S + +A + A + + + + ++ +V+T Sbjct: 186 TLLRAAGHDAVHPQFTGTSAYRGLVETSALREAYQAASLDEHLLNVPQMYLIEDGHVLTF 245 Query: 277 T------------ISEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSW 324 +S+ K + P + + D +L + + + Sbjct: 246 PVKKGKLIIIVAFVSDRSVAKPQWP----SDQPWVRPATTDEML---HRFAGAGEAVKTL 298 Query: 325 VTNGVPPGFGKELFESDLDRIMEHIKAAMEMVPVLKKADIINVVNGPITYSPDILPMVGP 384 +T+ P D D + ++ + ++ A + + G D Sbjct: 299 LTSIKSPTLWALH---DFDPLPTYVHGRVALIGDAAHAMLPHQGAGAGQGLEDA------ 349 Query: 385 HQGVRNYWVAIGFGYGIIHAGGVGKYL-----------SDWILHGEPPFDLIELDPNRYG 433 Y++A G + A + L S L +L E Sbjct: 350 ------YFMAELLGNPLHEASDIPALLEVYDDVRRGRASKVQLTSREAGELYEYRTPGVE 403 Query: 434 KWTTTQYTEAKARESYGFNNIVGYPKEERFAGRPTQ 469 + T ++R ++ +N +G E R A +P Sbjct: 404 RDTAKLKALLESRMNWIWNYDLG--AEARLAVKPAL 437 >1DOD-A nrPDB Length = 394 Score = 30.9 bits (68), Expect = 2.3, Method: Composition-based stats. Identities = 12/35 (34%), Positives = 20/35 (57%) Query: 49 RAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSE 83 + + IIG G G+ L L KAG+ +V+L ++ Sbjct: 2 KTQVAIIGAGPSGLLLGQLLHKAGIDNVILERQTP 36 >6QE4-A nrPDB Length = 327 Score = 30.9 bits (68), Expect = 2.3, Method: Composition-based stats. Identities = 41/301 (13%), Positives = 95/301 (31%), Gaps = 59/301 (19%) Query: 540 FNIKGQDSIRLLDHLFANVIPKVGFTN----------ISHMLTPKGRVYAELTVSHQSPG 589 ++G D+ L L N +P +H L +GR ++ + Sbjct: 30 LRVRGPDAAPFLLGLLTNELPLPSPAAAGAPPAARAGYAHFLNVQGRTLYDVILYGL--- 86 Query: 590 EFLLITGSGSELHDLRWIEEEAVKGGYDVEIKNITDELGVLGVAGPQA-RKVLQKLTSED 648 +E + G+ +E + + A ++ +K+T E Sbjct: 87 ------------------QEHSEVSGFLLECDSSVQG----ALQKHLALYRIRRKVTVEP 124 Query: 649 LSDDVFKFLQTKSLKVSNIPVTAIRISYTGELGWELYHRREDSVALYDAIMNAGQEEGID 708 + + S + R + R + + ++ + + Sbjct: 125 HPELRVWAVLPSSPEACGAASLQERAG-----AAAILIRDPRTARMGWRLLTQDEGPALV 179 Query: 709 NFG----TYAMNALRLEKAFRAWGLEMNCDTN-PLEAGLEYFVKLN-KPADFIGKQALKQ 762 G + + R + ++ PLE+ L + ++ +IG++ + Sbjct: 180 PGGRLGDLWDYHQHRYLQGVPEGVRDLPPGVALPLESNLAFMNGVSFTKGCYIGQELTAR 239 Query: 763 IKAKGL-KRRLVCLT----LATDDVDPEGNESIWYNGKVVGNTTSGSYSYSIQKSLAFAY 817 G+ ++RL + L T + P G + +G+ VG +G Q ++ A Sbjct: 240 THHMGVIRKRLFPVRFLDPLPTSGITP-GATVLTASGQTVGKFRAG------QGNVGLAL 292 Query: 818 V 818 + Sbjct: 293 L 293 >3RED-A nrPDB Length = 521 Score = 30.5 bits (67), Expect = 2.9, Method: Composition-based stats. Identities = 13/41 (31%), Positives = 22/41 (53%), Gaps = 2/41 (4%) Query: 45 QWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELT 85 + + + VI+GGG G LA L++ V++LE+ L Sbjct: 22 ELEGSYDYVIVGGGTSGCPLAATLSEK--YKVLVLERGTLP 60 >3EOQ-A nrPDB Length = 406 Score = 30.5 bits (67), Expect = 3.0, Method: Composition-based stats. Identities = 27/122 (22%), Positives = 36/122 (29%), Gaps = 17/122 (13%) Query: 390 NYWVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARESY 449 Y+V G GV +L + G P D+ L NR QY + E+ Sbjct: 27 GYFVKTGARDETKEESGVSHFLEHMVFKG--PEDMDALAVNRAFDRMGAQYNAFTSEEAT 84 Query: 450 GFNNIVG----YPKEERFAG--RPTQRVSGLYQ----RLESKCSMGFHAG-----WEQPH 494 + V Y FA RP R LE G W + Sbjct: 85 VYYGAVLPEFAYDLLGLFAKLLRPALREEDFQTEKLVILEEIARYQDRPGFMAYEWARAR 144 Query: 495 WF 496 +F Sbjct: 145 FF 146 >4B3J-A nrPDB Length = 736 Score = 30.5 bits (67), Expect = 3.1, Method: Composition-based stats. Identities = 23/116 (19%), Positives = 41/116 (35%), Gaps = 10/116 (8%) Query: 54 IIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHYDSI 113 ++G G +G +AY AKAG + V+L+ L A + + S Sbjct: 346 VLGAGMMGAGIAYVSAKAGYE--VVLKDVSLEAAAKGKGYSEKLEAKALERGRTTQERSD 403 Query: 114 KLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLIEPEKI 169 L ++ T F G + E K+++ + ++EP I Sbjct: 404 ALLARITP-TADAADF--KGVDFVIEAVFENQELKHKVF-----GEIEDIVEPNAI 451 >1MAF-H nrPDB Length = 373 Score = 30.5 bits (67), Expect = 3.5, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 26/76 (34%), Gaps = 1/76 (1%) Query: 388 VRNYWVAIGFGYGIIHAGGVGKYLSDWILHGEPPFDLIELDPNRYGKWTTTQYTEAKARE 447 ++ + + G G + H G G + H F L +R K T Y E Sbjct: 47 IQQWVLDAGSGSILGHVNG-GFLPNPVAAHSGSEFALASTSFSRIAKGKRTDYVEVFDPV 105 Query: 448 SYGFNNIVGYPKEERF 463 ++ + P RF Sbjct: 106 TFLPIADIELPDAPRF 121 >2RGJ-A nrPDB Length = 402 Score = 30.5 bits (67), Expect = 3.5, Method: Composition-based stats. Identities = 14/32 (43%), Positives = 19/32 (59%) Query: 51 ETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKS 82 + +I G G G+S A L +AG+ V LLE S Sbjct: 6 DILIAGAGIGGLSCALALHQAGIGKVTLLESS 37 >5W4C-A nrPDB Length = 371 Score = 30.2 bits (66), Expect = 4.0, Method: Composition-based stats. Identities = 24/106 (22%), Positives = 37/106 (34%), Gaps = 9/106 (8%) Query: 34 GEEKPPLSAETQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVV----LLEKSELTAGST 89 G +P + E K ++ VIIG G G + A +LA+A ++ V+ L T Sbjct: 15 GVREPKRTGEVSKKMHSKVVIIGSGPGGHTAAIYLARANLEPVLYEGMLANGFAPGGQLT 74 Query: 90 WHA-----AGLTTYFHPGINLKKIHYDSIKLYEKLEEETGQVVGFH 130 G + K S + K+ ET V Sbjct: 75 TTTDVENFPGFPEGVTGTEMMDKFRAQSERFGTKIITETVARVDLS 120 >6AH0-2 nrPDB Length = 895 Score = 30.2 bits (66), Expect = 4.4, Method: Composition-based stats. Identities = 11/28 (39%), Positives = 16/28 (57%), Gaps = 1/28 (3%) Query: 467 PTQRVSGLYQRLESKCSMGFHA-GWEQP 493 P ++ GL + CS G+HA GW +P Sbjct: 646 PNLKIPGLNSPIPESCSFGYHAGGWGKP 673 >5JCN-A nrPDB Length = 451 Score = 30.2 bits (66), Expect = 4.7, Method: Composition-based stats. Identities = 14/52 (26%), Positives = 24/52 (46%) Query: 32 REGEEKPPLSAETQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSE 83 RE ++ L A Q K + VI+GGG +G+ L+ L ++ + Sbjct: 163 REVDDADKLVAAIQAKKGGKAVIVGGGYIGLELSAALKINDFDVTMVFPEPW 214 >6ER9-A nrPDB Length = 549 Score = 29.8 bits (65), Expect = 5.2, Method: Composition-based stats. Identities = 25/140 (17%), Positives = 48/140 (34%), Gaps = 7/140 (5%) Query: 51 ETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGLTTYFHPGINLKKIHY 110 + V+IG G G+ + L VV +K++ G+ + +L + + Sbjct: 11 DAVVIGAGFGGIYAVHKLHNEQGLTVVGFDKADGPGGTWYWNRYPGALSDTESHLYRFSF 70 Query: 111 DSIKLYEKLEEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLIEPEKIQ 170 D L + + T QP + + V + + R G T +E E + Sbjct: 71 DRDLLQDGTWKTTYI----TQPEILEYLESVVDRFDLRRH-FRFGTEVTSAIYLEDENLW 125 Query: 171 EMFPLLNMNKVLAGLYNPGD 190 E+ + +V Y Sbjct: 126 EV--STDKGEVYRAKYVVNA 143 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.123 0.297 Lambda K H 0.267 0.0377 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 28,941,397 Number of Sequences: 36641 Number of extensions: 1153439 Number of successful extensions: 3893 Number of sequences better than 10.0: 194 Number of HSP's better than 10.0 without gapping: 186 Number of HSP's successfully gapped in prelim test: 98 Number of HSP's that attempted gapping in prelim test: 3471 Number of HSP's gapped (non-prelim): 343 length of query: 866 length of database: 10,336,785 effective HSP length: 106 effective length of query: 760 effective length of database: 6,452,839 effective search space: 4904157640 effective search space used: 4904157640 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 63 (29.0 bits)