BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9UI10 (523 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6O85-E nrPDB 1066 0.0 5B04-G nrPDB 303 1e-82 6I7T-C nrPDB 237 9e-63 5DBO-A nrPDB 171 7e-43 3A9C-A nrPDB 141 8e-34 5YG5-A nrPDB 137 9e-33 6O85-G nrPDB 105 6e-23 6JLZ-C nrPDB 91 2e-18 1VB5-A nrPDB 89 6e-18 6O81-C nrPDB 89 7e-18 5B04-A nrPDB 87 2e-17 6I3M-A nrPDB 73 3e-13 2YRF-A nrPDB 71 1e-12 1T9K-A nrPDB 65 9e-11 1T5O-A nrPDB 64 1e-10 4LDQ-A nrPDB 64 1e-10 2A0U-A nrPDB 61 1e-09 6A34-A nrPDB 50 3e-06 6I3M-E nrPDB 39 0.005 2PPY-A nrPDB 28 7.3 >6O85-E nrPDB Length = 523 Score = 1066 bits (2756), Expect = 0.0, Method: Compositional matrix adjust. Identities = 523/523 (100%), Positives = 523/523 (100%) Query: 1 MAAVAVAVREDSGSGMKAELPPGPGAVGREMTKEEKLQLRKEKKQQKKKRKEEKGAEPET 60 MAAVAVAVREDSGSGMKAELPPGPGAVGREMTKEEKLQLRKEKKQQKKKRKEEKGAEPET Sbjct: 1 MAAVAVAVREDSGSGMKAELPPGPGAVGREMTKEEKLQLRKEKKQQKKKRKEEKGAEPET 60 Query: 61 GSAVSAAQCQVGPTRELPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARKG 120 GSAVSAAQCQVGPTRELPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARKG Sbjct: 61 GSAVSAAQCQVGPTRELPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARKG 120 Query: 121 EQGGPPPKASPSTAGETPSGVKRLPEYPQVDDLLLRRLVKKPERQQVPTRKDYGSKVSLF 180 EQGGPPPKASPSTAGETPSGVKRLPEYPQVDDLLLRRLVKKPERQQVPTRKDYGSKVSLF Sbjct: 121 EQGGPPPKASPSTAGETPSGVKRLPEYPQVDDLLLRRLVKKPERQQVPTRKDYGSKVSLF 180 Query: 181 SHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDY 240 SHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDY Sbjct: 181 SHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDY 240 Query: 241 TTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSEL 300 TTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSEL Sbjct: 241 TTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSEL 300 Query: 301 RAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVV 360 RAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVV Sbjct: 301 RAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVV 360 Query: 361 VDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGT 420 VDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGT Sbjct: 361 VDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGT 420 Query: 421 AQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHA 480 AQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHA Sbjct: 421 AQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHA 480 Query: 481 SLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ 523 SLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ Sbjct: 481 SLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ 523 >5B04-G nrPDB Length = 467 Score = 303 bits (776), Expect = 1e-82, Method: Compositional matrix adjust. Identities = 154/350 (44%), Positives = 224/350 (64%), Gaps = 16/350 (4%) Query: 176 KVSLFSHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQ 235 +VS+FSHL R+ + +IP IHPA++RLGL+ + + GSN RCI LL+ + Sbjct: 119 QVSIFSHLDWRRRRTT----ENIPKD-IHPAVIRLGLKLANYKIFGSNQRCIDLLKTFKI 173 Query: 236 VIQDYTTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEE 295 VIQDY TP LSR L + +++L RPLS SM NAI+FL EI+ + ++E Sbjct: 174 VIQDYQTPYGTTLSRHLTTHINSQIAYLVSTRPLSISMGNAIRFLKLEISVLDIDLTDDE 233 Query: 296 AKSELRAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRR 355 K L ID Y++++I++A Q I + A +KI +GDVIL Y SS V+ +L A G++ Sbjct: 234 GKELLLEKIDSYIRDRIIIAGQVIVQAATEKIQDGDVILTYLHSSTVNDVLIHAKNVGKK 293 Query: 356 FRVVVVDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVM 415 FRVVVVDSRP EGR L+ L G+ +Y++I A SY++ EV+K+ LG HA+L+NG++ Sbjct: 294 FRVVVVDSRPEFEGRVCLKLLTEHGIECTYVMISALSYIMQEVTKIFLGGHAMLSNGALY 353 Query: 416 SRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELD--------DPDDLQCKR 467 SR GT+ ++L+ NVPV+ CCE+YKF ER+Q D+ V NEL DD + K Sbjct: 354 SRAGTSLISLLGHESNVPVIACCESYKFTERIQLDSLVYNELAPGDQLVNMGVDDFEEKP 413 Query: 468 GEHVALANWQNHASLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLR 517 G LANW++ +L+LL+L YDVTPP L+ + + E+G++P +SVP ++ Sbjct: 414 G---VLANWKSVKNLKLLSLKYDVTPPRLITVCVCEMGLLPSTSVPAIIN 460 >6I7T-C nrPDB Length = 651 Score = 237 bits (604), Expect = 9e-63, Method: Compositional matrix adjust. Identities = 139/377 (36%), Positives = 198/377 (52%), Gaps = 61/377 (16%) Query: 202 VIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDYTTPPNEELSRDLVNKLKPYMS 261 +IHP+++ L + + GS RCIA+L Q VI+DY TP LSR+L + L + Sbjct: 269 LIHPSILLLTSHLAHYKIVGSIPRCIAMLEVFQIVIKDYQTPKGTTLSRNLTSYLSHQID 328 Query: 262 FLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSELRAAIDRYVQEKIVLAAQAISR 321 L + RPLS +M NAI++L +EI+ + S ++ AK +L I ++ +EKI LA Q I Sbjct: 329 LLKKARPLSVTMGNAIRWLKQEISLIDPSTPDKAAKKDLCEKIGQFAKEKIELADQLIID 388 Query: 322 FAYQKISNGDVILVYGCSSLVSR-ILQEAWTEGRRFRVVVVDSRPWLEGRHTLRSLVHAG 380 A +I I+ YG S +++ +L A + + +V+VVDSRP EGR +L +AG Sbjct: 389 NASTQIEESTTIVTYGSSKVLTELLLHNAISLKKNIKVIVVDSRPLFEGRKMAETLRNAG 448 Query: 381 VPASYLLIPAASYVLP-EVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCE 439 V Y LI + + +V V LGAH++L+NG + SR GTA LA+ A+ N+PVLVCCE Sbjct: 449 VNVMYALITSLDTIFNMDVDYVFLGAHSILSNGFLYSRAGTAMLAMSAKRRNIPVLVCCE 508 Query: 440 TYKFCERVQTDAFVSNELDDPDDLQC--------KRGEHVALAN---------------- 475 + KF +RVQ D+ NEL DP+DL +RG AL N Sbjct: 509 SLKFSQRVQLDSVTFNELADPNDLVNIDYENPVERRGNKGALLNQFIKERKFEKKKLAME 568 Query: 476 -----------------------------------WQNHASLRLLNLVYDVTPPELVDLV 500 WQ SL ++N++YD+TPPE + V Sbjct: 569 NKPKGNKIGGKKGSEGESKDASNEEDSNSKNILDGWQELPSLNIVNILYDLTPPEYIKKV 628 Query: 501 ITELGMIPCSSVPVVLR 517 ITE G +P SSVPV+LR Sbjct: 629 ITEFGALPPSSVPVILR 645 >5DBO-A nrPDB Length = 466 Score = 171 bits (433), Expect = 7e-43, Method: Compositional matrix adjust. Identities = 143/472 (30%), Positives = 212/472 (44%), Gaps = 98/472 (20%) Query: 62 SAVSAAQCQVGPTRELPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARKGE 121 SAV+AA G P ++ + + ++ A+ + KQE ++ Sbjct: 69 SAVAAA-----------------GQPAQQSGSAGADSKGAAKGKGKQEGQQV-------- 103 Query: 122 QGGPPPKA----SPSTAGETPSGVKRLPEYPQVDDLLLRRLVKKPERQQVPTRKDYGSKV 177 PPK PS +G PS + +V+K R +P Sbjct: 104 ----PPKGVLVHRPSVSGRRPSIM----------------VVEKDARSGIP--------- 134 Query: 178 SLFSHLPQYSRQNSLTQFMSIPSSV----IHPAMVRLGLQYSQGLVSGSNARCIALLRAL 233 FSH+P R IP+S +HPA++ +G Q + + S +R A L A Sbjct: 135 ECFSHIPMAKR---------IPTSQAHKDVHPAVLAVGQQMATFALKDSISRLKATLLAF 185 Query: 234 QQVIQDYTTPPNEELSRDLV-NKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKR 292 ++VI+ Y TP LSR V + L P + +LT+CRP+ +M NAI+ L ++ + Sbjct: 186 RKVIESYETPKGNSLSRHFVPHVLNPQIEYLTECRPMCFAMGNAIRLLKAKVNKFDINTP 245 Query: 293 EEEAKSELRAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTE 352 E+EAK L ID + E+I LA I+R A Q I++GD I+ YG LV + L A E Sbjct: 246 EDEAKEGLLEWIDFLINERITLAEYVIARNAAQSINDGDTIVTYGRHRLVEKTLLRARKE 305 Query: 353 GRRFRVVVVDSRPWLEGRHTLRSLVHAGVPASYL-LIPAASYVLPEVSKVLLGAHALLAN 411 G+ F V V+D EG+ + L HAG+P Y + +P S V LG A+ AN Sbjct: 306 GKSFNVTVLDDPYVGEGKELAKVLRHAGIPVLYSPNLGGLRSKVPAASNVFLGGEAIFAN 365 Query: 412 GSVMSRVGTAQLALVARAHNVPVLVCCETYKFC-ERVQTDAFVSNELD-DPDDLQCKRGE 469 GS+ + GTA +A+ A V+V CET F ERV DA NE+D + + C R Sbjct: 366 GSLHAPSGTADVAMAATNAGAKVIVLCETINFDRERVSVDALTYNEIDPERNTGDCFR-- 423 Query: 470 HVALANWQNHASLRLLNLVYDVTPPELVDLVITEL----GMIPCSSVPVVLR 517 L++D T + VITE+ G P ++ +LR Sbjct: 424 -----------------LLFDNTHERYITGVITEIEFGGGNSPAQAILALLR 458 >3A9C-A nrPDB Length = 338 Score = 141 bits (355), Expect = 8e-34, Method: Compositional matrix adjust. Identities = 82/270 (30%), Positives = 146/270 (54%), Gaps = 12/270 (4%) Query: 251 DLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSELRAAIDRYVQE 310 + ++K L + RP + S+ NA++++ SS + E +LR I +E Sbjct: 63 EFWKEMKQAAKILFETRPTAVSLPNALRYVMHRGKIAYSSGADLE---QLRFVIINAAKE 119 Query: 311 KIVLAAQAISR---FAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVVVDSRPWL 367 I + +A+ R F ++I +GDVI+ + S +++ AW +G+ +V+V ++RP Sbjct: 120 FIHNSEKALERIGEFGAKRIEDGDVIMTHCHSKAAISVMKTAWEQGKDIKVIVTETRPKW 179 Query: 368 EGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVA 427 +G+ T + L G+P Y++ AA + + KV++GA ++ NG+V++++GTA +AL A Sbjct: 180 QGKITAKELASYGIPVIYVVDSAARHYMKMTDKVVMGADSITVNGAVINKIGTALIALTA 239 Query: 428 RAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHASLRLLNL 487 + H V ++ ETYKF V E+ DP ++ + L W ++ + N Sbjct: 240 KEHRVWTMIAAETYKFHPETMLGQLVEIEMRDPTEVIPED----ELKTWPK--NIEVWNP 293 Query: 488 VYDVTPPELVDLVITELGMIPCSSVPVVLR 517 +DVTPPE VD++ITE G+IP + +LR Sbjct: 294 AFDVTPPEYVDVIITERGIIPPYAAIDILR 323 >5YG5-A nrPDB Length = 324 Score = 137 bits (346), Expect = 9e-33, Method: Compositional matrix adjust. Identities = 79/270 (29%), Positives = 150/270 (55%), Gaps = 12/270 (4%) Query: 251 DLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITS--VGSSKREEEAKSELRAAIDR-Y 307 +L N+LK L RP + S+ NA++++ + + +G + E + + +A + Y Sbjct: 49 ELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFIY 108 Query: 308 VQEKIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVVVDSRPWL 367 EK A + I ++I +GD+I+ + S ++++A+ +G+ +V+V ++RP Sbjct: 109 NSEK---AIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKW 165 Query: 368 EGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVA 427 +G+ T + L G+P Y++ AA + + KV++GA ++ ANG+V++++GT+ +AL A Sbjct: 166 QGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTA 225 Query: 428 RAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHASLRLLNL 487 + H V V++ ETYKF V E+ DP ++ + L W ++ + N Sbjct: 226 KEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEE----ELRTWPK--NIEVWNP 279 Query: 488 VYDVTPPELVDLVITELGMIPCSSVPVVLR 517 +DVTPPE +D++ITE G+IP + +L+ Sbjct: 280 AFDVTPPEYIDVIITERGIIPPYAAIDILK 309 >6O85-G nrPDB Length = 305 Score = 105 bits (261), Expect = 6e-23, Method: Compositional matrix adjust. Identities = 63/202 (31%), Positives = 107/202 (52%), Gaps = 8/202 (3%) Query: 311 KIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVVVDSRPWLEGR 370 +I L+ I+ + I +G IL + S +V R+L+ A +RF V V +S+P L G+ Sbjct: 103 RISLSRNKIADLCHTFIKDGATILTHAYSRVVLRVLEAAVAAKKRFSVYVTESQPDLSGK 162 Query: 371 HTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAH 430 ++L H VP + +L A Y++ + V++GA ++ NG +++++GT Q+A+ A+A Sbjct: 163 KMAKALCHLNVPVTVVLDAAVGYIMEKADLVIVGAEGVVENGGIINKIGTNQMAVCAKAQ 222 Query: 431 NVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHASLRLLNLVYD 490 N P V E++KF F N+ D PD + K L Q L+ + D Sbjct: 223 NKPFYVVAESFKFVR-----LFPLNQQDVPDKFKYKAD---TLKVAQTGQDLKEEHPWVD 274 Query: 491 VTPPELVDLVITELGMIPCSSV 512 T P L+ L+ T+LG++ S+V Sbjct: 275 YTAPSLITLLFTDLGVLTPSAV 296 >6JLZ-C nrPDB Length = 399 Score = 90.5 bits (223), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 61/187 (32%), Positives = 93/187 (49%), Gaps = 12/187 (6%) Query: 327 ISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVVVDSRPWLE-GRHTL-RSLVHAGVPAS 384 + + ++IL GCS V L+ A + R+F V+V + P + G H + + L AG+ + Sbjct: 205 LHSNEIILTQGCSKTVEAFLRFA-AKKRKFSVIVAEGFPNNQKGSHAMAKRLAQAGIDTT 263 Query: 385 YLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFC 444 + ++ V+KV+LG HA+L NG +++ G +A AR H PV+VC YK Sbjct: 264 VISDATIFAIMSRVNKVILGTHAILGNGGLVTYSGAQLVAQAARHHATPVVVCSGIYKLS 323 Query: 445 ERVQTDAFVSNELDDPDDLQC-KRGEHVALANWQNHASLRLLNLVYDVTPPELVDLVITE 503 D +L PD + G+ ++ A +LN YD PP+LVDL IT Sbjct: 324 PVYPYDLESIIQLSSPDKIMSFNEGDLISRA--------EILNPYYDYIPPDLVDLFITN 375 Query: 504 LGMIPCS 510 LG P S Sbjct: 376 LGGYPPS 382 >1VB5-A nrPDB Length = 276 Score = 88.6 bits (218), Expect = 6e-18, Method: Compositional matrix adjust. Identities = 73/270 (27%), Positives = 125/270 (46%), Gaps = 47/270 (17%) Query: 245 NEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFL----NKEIT---SVGSSKREEEAK 297 +E L D + +L+ + + P AS++N +F+ ++I ++ +R EEAK Sbjct: 40 DESLLEDAIMELREE---VVKVNPSMASLYNLARFIPVTNRRDILKSRALEFLRRMEEAK 96 Query: 298 SELRAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFR 357 EL + Q I +GDVI+ + SS V I++ A +RF+ Sbjct: 97 REL-------------------ASIGAQLIDDGDVIITHSFSSTVLEIIRTAKERKKRFK 137 Query: 358 VVVVDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSR 417 V++ +S P EG H R L +G+ + E S ++GA + +G V+++ Sbjct: 138 VILTESSPDYEGLHLARELEFSGIEFEVITDAQMGLFCREASIAIVGADMITKDGYVVNK 197 Query: 418 VGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQ 477 GT LAL + +P V ETYKF +++ + E D RG Sbjct: 198 AGTYLLALACHENAIPFYVAAETYKFHPTLKSGDVMLMERD------LIRG--------- 242 Query: 478 NHASLRLLNLVYDVTPPELVDLVITELGMI 507 ++R+ N+++DVTP + V +ITELG++ Sbjct: 243 ---NVRIRNVLFDVTPWKYVRGIITELGIV 269 >6O81-C nrPDB Length = 368 Score = 88.6 bits (218), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 66/235 (28%), Positives = 116/235 (49%), Gaps = 23/235 (9%) Query: 280 LNKEITSVGSSKREEEAKSELRAAIDRYVQEKIV--------LAAQAISRFAYQKISNGD 331 L+K +TS G ++ ++L++ I + E +V +AAQA+ + I + + Sbjct: 126 LHKLLTSGGLNEDFSFHYAQLQSNIIEAINELLVELEGTMENIAAQAL-----EHIHSNE 180 Query: 332 VILVYGCSSLVSRILQEAWTEGRRFRVVVVDSRPWLEGRHTLRSLVHAGVPASYLLIPAA 391 VI+ G S V L+EA R+F V+V + P+ +G +L AG+ + + A Sbjct: 181 VIMTIGFSRTVEAFLKEA-ARKRKFHVIVAECAPFCQGHEMAVNLSKAGIETTVMTDAAI 239 Query: 392 SYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDA 451 V+ V+KV++G +LANG++ + GT LAL A+ H+ P++VC +K + + Sbjct: 240 FAVMSRVNKVIIGTKTILANGALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEE 299 Query: 452 FVSNELDDPDD-LQCKRGEHVALANWQNHASLRLLNLVYDVTPPELVDLVITELG 505 ++ P++ L G+ L H V+D PPEL+ L I+ +G Sbjct: 300 DSFHKFVAPEEVLPFTEGD--ILEKVSVHCP------VFDYVPPELITLFISNIG 346 >5B04-A nrPDB Length = 341 Score = 87.0 bits (214), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 79/256 (30%), Positives = 120/256 (46%), Gaps = 17/256 (6%) Query: 269 LSASMHNAIKFLNKEITSVGSSKREEEAKSELRAAIDRYVQEKIVLAAQAISRFAYQKIS 328 LSA +F+ + + VG E+ K L ++Q + Q I+ Y I Sbjct: 79 LSAGCDIFQRFVTRSLHDVGDF---EQCKRHLVENGKLFIQ-RARACRQRIAHLGYPLIR 134 Query: 329 NGDVILVYGCSSLVSRILQEAWTEGRRFRVVVVDSRPWLEGRHTLRSLVHAGVPASYLLI 388 +G VIL +G S V+ +L A RF+V V +SRP G R+L +A +P +L Sbjct: 135 DGSVILTHGFSRGVAAVLLAAAKRHVRFKVFVTESRPSGSGCLMTRTLKNACIPTCMVLD 194 Query: 389 PAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERV- 447 A S+ + V VL+GA ++ NG +++++GT QLA+ A+ + P E++KF Sbjct: 195 SAVSFTMNRVDLVLVGAEGVVENGGLINQIGTFQLAVFAKHAHKPFYAVAESHKFVRMFP 254 Query: 448 --QTDAFVSN---ELDDPD-DLQCKRGEHVALANWQNHASLRL------LNLVYDVTPPE 495 Q D S E DDP + E + + H L + N DVTPPE Sbjct: 255 LSQYDIPFSRPILEFDDPSPETVHPEPEPIPTPSDAIHNELIMNEEQIRNNPTLDVTPPE 314 Query: 496 LVDLVITELGMIPCSS 511 V +IT+LG+I S Sbjct: 315 FVSGLITDLGIIDSKS 330 >6I3M-A nrPDB Length = 305 Score = 73.2 bits (178), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 40/126 (31%), Positives = 66/126 (52%) Query: 319 ISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVVVDSRPWLEGRHTLRSLVH 378 I+ I++ D+ILV+G S V +L A + RFR VV +SRP +G L Sbjct: 112 IAEIGVDFIADDDIILVHGYSRAVFSLLNHAANKFIRFRCVVTESRPSKQGNQLYTLLEQ 171 Query: 379 AGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCC 438 G+P + ++ A V+ +V KV +GA + +G +++ VGT + ++A P V Sbjct: 172 KGIPVTLIVDSAVGAVIDKVDKVFVGAEGVAESGGIINLVGTYSVGVLAHNARKPFYVVT 231 Query: 439 ETYKFC 444 E++KF Sbjct: 232 ESHKFV 237 >2YRF-A nrPDB Length = 374 Score = 70.9 bits (172), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 77/304 (25%), Positives = 139/304 (45%), Gaps = 33/304 (10%) Query: 219 VSGSNARCIALLRALQQVIQDYTTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIK 278 V G+ A I L +D T E R +L+ +L RP + ++ A++ Sbjct: 71 VRGAPAIGITAAFGLALAAKDIETDNVTEFRR----RLEDIKQYLNSSRPTAINLSWALE 126 Query: 279 FLNKEITSVGSSKREEEAKSEL-RAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILV-- 335 L+ SV ++ EAK+ L AI V+++ + I + A Q GD I+ Sbjct: 127 RLSH---SVENAISVNEAKTNLVHEAIQIQVEDE--ETCRLIGQNALQLFKKGDRIMTIC 181 Query: 336 ---------YGCSSLVSRILQEAWTEGRRFRVVVVDSRPWLEG-RHTLRSLVHAGVPASY 385 YG ++L L + G + ++RP L+G R T L+ G+ + Sbjct: 182 NAGSIATSRYG-TALAPFYLAKQKDLG--LHIYACETRPVLQGSRLTAWELMQGGIDVTL 238 Query: 386 LLIPAASYVLPE--VSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKF 443 + A++ + E +S V++GA + NG +++GT LA++A A ++P V F Sbjct: 239 ITDSMAAHTMKEKQISAVIVGADRIAKNGDTANKIGTYGLAILANAFDIPFFVAAPLSTF 298 Query: 444 CERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHASLRLLNLVYDVTPPELVDLVITE 503 +V+ A + E DP++++ G A +N + + N +D+TP +L+ +ITE Sbjct: 299 DTKVKCGADIPIEERDPEEVRQISGVRTAPSN------VPVFNPAFDITPHDLISGIITE 352 Query: 504 LGMI 507 G++ Sbjct: 353 KGIM 356 >1T9K-A nrPDB Length = 347 Score = 64.7 bits (156), Expect = 9e-11, Method: Compositional matrix adjust. Identities = 51/202 (25%), Positives = 97/202 (48%), Gaps = 17/202 (8%) Query: 317 QAISRFAYQKISNGDVILVY---GCSSLVSR-----ILQEAWTEGRRFRVVVVDSRPWLE 368 +AI + Q I +G IL + G + V +++ A G+R RV ++RP+L+ Sbjct: 136 KAIGKNGAQLIKDGSTILTHCNAGALATVDYGTALGVIRAAVESGKRIRVFADETRPYLQ 195 Query: 369 G-RHTLRSLVHAGVPASYLLIPAASYVLPE--VSKVLLGAHALLANGSVMSRVGTAQLAL 425 G R T L+ G+ + A +++ + V++GA + NG +++GT LA+ Sbjct: 196 GARLTAWELMKDGIEVYVITDNMAGWLMKRGLIDAVVVGADRIALNGDTANKIGTYSLAV 255 Query: 426 VARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHASLRLL 485 +A+ +N+P V +++ + E P+++ G +A +++L Sbjct: 256 LAKRNNIPFYVAAPVSTIDPTIRSGEEIPIEERRPEEVTHCGGNRIA------PEGVKVL 309 Query: 486 NLVYDVTPPELVDLVITELGMI 507 N +DVT L+ +ITE G+I Sbjct: 310 NPAFDVTENTLITAIITEKGVI 331 >1T5O-A nrPDB Length = 351 Score = 63.9 bits (154), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 71/287 (24%), Positives = 135/287 (47%), Gaps = 30/287 (10%) Query: 251 DLVNKLKPYMSFLTQCRPLSASMHNAI-KFLNKEITSVGSSKREEEAKSELRAAIDRYVQ 309 +L LK FL RP + ++ I + LN ++ EE + LR A + Sbjct: 72 ELKEHLKKAADFLASTRPTAVNLFVGIERALN---AALKGESVEEVKELALREA--EKLA 126 Query: 310 EKIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRI--------LQEAWTEGRRFRVVVV 361 E+ V + + + + + +GDV+L Y + ++ + ++ A +G+ RV+ Sbjct: 127 EEDVERNRKMGEYGAELLEDGDVVLTYCNAGRLATVDWGTALGVVRSAVEQGKEIRVIAC 186 Query: 362 DSRPWLEG-RHTLRSLVHAGVPASYLLIPAASYVLPE--VSKVLLGAHALLANGSVMSRV 418 ++RP +G R T L+ G+ + + V+ + V KV++GA ++ + +V +++ Sbjct: 187 ETRPLNQGSRLTCWELMEDGIDVTLITDSMVGIVMQKGMVDKVIVGADRIVRD-AVFNKI 245 Query: 419 GTAQLALVARAHNVPVLVCCETYKF-CERVQTDAFVSNELDDPDDLQCKRGEHVALANWQ 477 GT +++VA+ HN+P V F ER D + E + + C + + L Sbjct: 246 GTYTVSVVAKHHNIPFYVAAPKATFDWERTAKDVVIE-ERPREELIFCGKRQIAPL---- 300 Query: 478 NHASLRLLNLVYDVTPPELVDLVITELGMI--PCS-SVPVVLRVKSS 521 ++++ N +D TP E V +ITE G+I P +VP VL+ + Sbjct: 301 ---NVKVYNPAFDPTPLENVTALITEYGVIYPPYEVNVPKVLKFEGG 344 >4LDQ-A nrPDB Length = 369 Score = 63.9 bits (154), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 69/288 (23%), Positives = 129/288 (44%), Gaps = 52/288 (18%) Query: 253 VNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSELRAAIDRYVQEKI 312 V ++ +SFL RP + +M A +++ V + + E E +E V+E++ Sbjct: 76 VAFVRDKLSFLVTARPTAVNMARA----ARDLADVAAREAEREGATE------EAVRERV 125 Query: 313 VLAAQAI---------------SRFAYQKI--SNGDVILVYGCSS---------LVSRIL 346 + + + +R +++ S G V ++ C++ ++ Sbjct: 126 ICCTEDMLEKDLRDNRSIGDLGARHLLERVAPSGGKVTVLTHCNTGALATAGYGTALGVI 185 Query: 347 QEAWTEGRRFRVVVVDSRPWLEG-RHTLRSLVHAGVPASYLL--IPAASYVLPEVSKVLL 403 + + GR ++RP+ +G R T LV+ +PA+ + + AA+ VS V++ Sbjct: 186 RSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGVSAVVV 245 Query: 404 GAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDL 463 GA ++ANG ++VGT QLA+VA+ H +P V + R++T + E +L Sbjct: 246 GADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEERPGQEL 305 Query: 464 QCKRGEHVA---LANWQNHASLRLLNLVYDVTPPELV-DLVITELGMI 507 G +A + W N +DVTP +L+ +ITELG+ Sbjct: 306 TDVNGVRIAAPGIGVW---------NPAFDVTPHDLITGGIITELGVF 344 >2A0U-A nrPDB Length = 383 Score = 61.2 bits (147), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 76/309 (24%), Positives = 137/309 (44%), Gaps = 24/309 (7%) Query: 227 IALLRALQQVIQDYTTPPNEEL--SRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEI 284 IA+ AL + N EL R++ L F+ RP + ++ N ++ L ++ Sbjct: 66 IAVSAALGIAVATQRKAANGELKSGREVQTFLLTSCDFVMTSRPTAVNLFNCLRDLKAQV 125 Query: 285 TSVGSSKREEE---AKSELRAAI---DRYVQEKIVLAAQAISRFAYQKISNGDVILVYGC 338 + +K E A EL A+ D E I+ A A + V ++ C Sbjct: 126 DKLDPTKAAAEVAQAFVELAEAVYTNDVAFNEGIMRHGAAHILAAAKAEGRDKVSILTIC 185 Query: 339 SS---LVSR------ILQEAWTEGRRFRVVVVDSRPWLEG-RHTLRSLVHAGVPASYLLI 388 ++ SR ++++ + +G+ RV ++RPW +G R T+ V +P + + Sbjct: 186 NTGALATSRYGTALGVVRQLFYDGKLERVYACETRPWNQGARLTVYECVQEDIPCTLICD 245 Query: 389 PAASYVLP--EVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCER 446 AAS ++ ++ V++GA + NG +++GT LA+ A+ H V + V T + Sbjct: 246 GAASSLMLNRKIDAVVVGADRICQNGDTANKIGTYNLAVSAKFHGVKLYVAAPTTTLDVK 305 Query: 447 VQTDAFVSNELDDPDDLQCKRGEHVALANWQNHASLRLLNLVYDVTPPELVD-LVITELG 505 + V E +P ++ + H L + N V+D+TP EL+ +ITE G Sbjct: 306 TASGNHVEIEEREPTEITTNLVTKQRVVADGPH--LSIWNPVFDITPSELITGGIITEKG 363 Query: 506 M-IPCSSVP 513 + P +S P Sbjct: 364 VQAPAASAP 372 >6A34-A nrPDB Length = 364 Score = 49.7 bits (117), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 35/149 (23%), Positives = 74/149 (49%), Gaps = 10/149 (6%) Query: 362 DSRPWLEG-RHTLRSLVHAGVPASYLLIPAASYVLPE--VSKVLLGAHALLANGSVMSRV 418 ++RP L+G R + + G+ + AA++V+ + V +++GA ++ANG +++ Sbjct: 200 ETRPVLQGARLSAWEYSYDGLNVKLIADNAAAFVMQQGFVDAIIVGADRIVANGDFANKI 259 Query: 419 GTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQN 478 GT LA++AR H +P +++ + E P+++ G +A Sbjct: 260 GTYMLAVLAREHGIPFFAVAPLSSIDMELKSGKDIPIEERSPEEVLTCGGCRIA------ 313 Query: 479 HASLRLLNLVYDVTPPELVDLVITELGMI 507 + + N +DVTP + + +IT+ G++ Sbjct: 314 -PDVPVYNPAFDVTPHKYLTGIITDRGVV 341 >6I3M-E nrPDB Length = 381 Score = 38.9 bits (89), Expect = 0.005, Method: Compositional matrix adjust. Identities = 36/138 (26%), Positives = 53/138 (38%), Gaps = 18/138 (13%) Query: 369 GRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANG-SVMSRVGTAQLALVA 427 +H + +LV VP S A ++ V KV++G A+ NG ++ S G + + A Sbjct: 234 AQHNIETLV---VPDS-----AVFALMSRVGKVIIGTKAVFVNGGTISSNSGVSSVCECA 285 Query: 428 RAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHASLRLLNL 487 R PV YK D E G L L +N Sbjct: 286 REFRTPVFAVAGLYKLSPLYPFDVEKFVEFG---------GSQRILPRMDPRKRLDTVNQ 336 Query: 488 VYDVTPPELVDLVITELG 505 + D PPE +D+ IT +G Sbjct: 337 ITDYVPPENIDIYITNVG 354 >2PPY-A nrPDB Length = 265 Score = 28.5 bits (62), Expect = 7.3, Method: Compositional matrix adjust. Identities = 20/56 (35%), Positives = 29/56 (51%), Gaps = 6/56 (10%) Query: 209 RLGL-QYSQGLVSGSN-----ARCIALLRALQQVIQDYTTPPNEELSRDLVNKLKP 258 ++GL + S G+++G+ AR I RAL I T P E L LVN++ P Sbjct: 134 KIGLPEVSLGVLAGTGGTQRLARLIGYSRALDMNITGETITPQEALEIGLVNRVFP 189 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6O85-E nrPDB 758 0.0 5B04-G nrPDB 424 e-119 5DBO-A nrPDB 382 e-106 6I7T-C nrPDB 345 3e-95 3A9C-A nrPDB 321 4e-88 5YG5-A nrPDB 309 2e-84 2YRF-A nrPDB 272 2e-73 2A0U-A nrPDB 272 3e-73 1T9K-A nrPDB 270 1e-72 1T5O-A nrPDB 260 1e-69 5B04-A nrPDB 245 2e-65 1VB5-A nrPDB 236 2e-62 6O85-G nrPDB 232 4e-61 4LDQ-A nrPDB 232 4e-61 6O81-C nrPDB 230 1e-60 6A34-A nrPDB 224 5e-59 6I3M-A nrPDB 219 2e-57 6JLZ-C nrPDB 205 5e-53 Sequences not found previously or not previously below threshold: 6I3M-E nrPDB 142 3e-34 6BYS-B nrPDB 39 0.005 5A1W-H nrPDB 37 0.024 2WHD-A nrPDB 34 0.16 3RQF-A nrPDB 33 0.24 6FYY-r nrPDB 33 0.28 3D8X-A nrPDB 33 0.30 2JGP-A nrPDB 33 0.45 4IOV-A nrPDB 32 0.54 3W0L-B nrPDB 32 0.66 3TSB-A nrPDB 32 0.85 5W4C-A nrPDB 31 1.1 6QX9-4A nrPDB 31 1.8 1TYG-A nrPDB 31 1.9 6MAT-A nrPDB 29 3.8 4D5Y-M nrPDB 29 4.4 5L3D-A nrPDB 29 6.6 >6O85-E nrPDB Length = 523 Score = 758 bits (1957), Expect = 0.0, Method: Composition-based stats. Identities = 523/523 (100%), Positives = 523/523 (100%) Query: 1 MAAVAVAVREDSGSGMKAELPPGPGAVGREMTKEEKLQLRKEKKQQKKKRKEEKGAEPET 60 MAAVAVAVREDSGSGMKAELPPGPGAVGREMTKEEKLQLRKEKKQQKKKRKEEKGAEPET Sbjct: 1 MAAVAVAVREDSGSGMKAELPPGPGAVGREMTKEEKLQLRKEKKQQKKKRKEEKGAEPET 60 Query: 61 GSAVSAAQCQVGPTRELPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARKG 120 GSAVSAAQCQVGPTRELPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARKG Sbjct: 61 GSAVSAAQCQVGPTRELPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARKG 120 Query: 121 EQGGPPPKASPSTAGETPSGVKRLPEYPQVDDLLLRRLVKKPERQQVPTRKDYGSKVSLF 180 EQGGPPPKASPSTAGETPSGVKRLPEYPQVDDLLLRRLVKKPERQQVPTRKDYGSKVSLF Sbjct: 121 EQGGPPPKASPSTAGETPSGVKRLPEYPQVDDLLLRRLVKKPERQQVPTRKDYGSKVSLF 180 Query: 181 SHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDY 240 SHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDY Sbjct: 181 SHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDY 240 Query: 241 TTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSEL 300 TTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSEL Sbjct: 241 TTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSEL 300 Query: 301 RAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVV 360 RAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVV Sbjct: 301 RAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVV 360 Query: 361 VDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGT 420 VDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGT Sbjct: 361 VDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGT 420 Query: 421 AQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHA 480 AQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHA Sbjct: 421 AQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHA 480 Query: 481 SLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ 523 SLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ Sbjct: 481 SLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ 523 >5B04-G nrPDB Length = 467 Score = 424 bits (1089), Expect = e-119, Method: Composition-based stats. Identities = 170/464 (36%), Positives = 253/464 (54%), Gaps = 12/464 (2%) Query: 61 GSAVSAAQCQVGPTRELPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARKG 120 G + A+ + ES GT + S E + + + ++A KQA + Sbjct: 2 GFSAEQAKKDGKDQSPVSESSSVGGTSPATASSVVSPNEPKLSGKEAKALKKARKQASRR 61 Query: 121 EQGGPPPKASPSTAGETPSGVKRLPEYPQVDDLLLRRLVKKPERQQVPTRKD--YGSKVS 178 + +P E Q + PE K +VS Sbjct: 62 AKAEAAAANNPPGVSEEKKVAIPNKNSNQQKKASKQNPQNSPETDANLQEKKIFEEKQVS 121 Query: 179 LFSHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQ 238 +FSHL R+ + +IP IHPA++RLGL+ + + GSN RCI LL+ + VIQ Sbjct: 122 IFSHLDWRRRRTT----ENIPKD-IHPAVIRLGLKLANYKIFGSNQRCIDLLKTFKIVIQ 176 Query: 239 DYTTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKS 298 DY TP LSR L + +++L RPLS SM NAI+FL EI+ + ++E K Sbjct: 177 DYQTPYGTTLSRHLTTHINSQIAYLVSTRPLSISMGNAIRFLKLEISVLDIDLTDDEGKE 236 Query: 299 ELRAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRV 358 L ID Y++++I++A Q I + A +KI +GDVIL Y SS V+ +L A G++FRV Sbjct: 237 LLLEKIDSYIRDRIIIAGQVIVQAATEKIQDGDVILTYLHSSTVNDVLIHAKNVGKKFRV 296 Query: 359 VVVDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRV 418 VVVDSRP EGR L+ L G+ +Y++I A SY++ EV+K+ LG HA+L+NG++ SR Sbjct: 297 VVVDSRPEFEGRVCLKLLTEHGIECTYVMISALSYIMQEVTKIFLGGHAMLSNGALYSRA 356 Query: 419 GTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQC-----KRGEHVAL 473 GT+ ++L+ NVPV+ CCE+YKF ER+Q D+ V NEL D L + L Sbjct: 357 GTSLISLLGHESNVPVIACCESYKFTERIQLDSLVYNELAPGDQLVNMGVDDFEEKPGVL 416 Query: 474 ANWQNHASLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLR 517 ANW++ +L+LL+L YDVTPP L+ + + E+G++P +SVP ++ Sbjct: 417 ANWKSVKNLKLLSLKYDVTPPRLITVCVCEMGLLPSTSVPAIIN 460 >5DBO-A nrPDB Length = 466 Score = 382 bits (980), Expect = e-106, Method: Composition-based stats. Identities = 160/535 (29%), Positives = 236/535 (44%), Gaps = 104/535 (19%) Query: 2 AAVAVAVREDSGSGMKAELPPGPGAVGRE---MTKEEKLQLRKEKKQQKKKRKEEKGAEP 58 A+ A A +D G K PP P A EKL + K + K +++ + A Sbjct: 9 ASPATATTQD---GAKGAAPPNPAASINSPAPAANPEKLTPAQLKAKAKAEKQARRAAAK 65 Query: 59 ETGSAVSAAQCQVGPTRELPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQAR 118 E SAV+AA G P ++ + + ++ A+ + KQE ++ Sbjct: 66 EAKSAVAAA-----------------GQPAQQSGSAGADSKGAAKGKGKQEGQQV----- 103 Query: 119 KGEQGGPPPKA----SPSTAGETPSGVKRLPEYPQVDDLLLRRLVKKPERQQVPTRKDYG 174 PPK PS +G PS + +V+K R +P Sbjct: 104 -------PPKGVLVHRPSVSGRRPSIM----------------VVEKDARSGIP------ 134 Query: 175 SKVSLFSHLPQYSRQNSLTQFMSIPSSV----IHPAMVRLGLQYSQGLVSGSNARCIALL 230 FSH+P R IP+S +HPA++ +G Q + + S +R A L Sbjct: 135 ---ECFSHIPMAKR---------IPTSQAHKDVHPAVLAVGQQMATFALKDSISRLKATL 182 Query: 231 RALQQVIQDYTTPPNEELSRDLVNK-LKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGS 289 A ++VI+ Y TP LSR V L P + +LT+CRP+ +M NAI+ L ++ Sbjct: 183 LAFRKVIESYETPKGNSLSRHFVPHVLNPQIEYLTECRPMCFAMGNAIRLLKAKVNKFDI 242 Query: 290 SKREEEAKSELRAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRILQEA 349 + E+EAK L ID + E+I LA I+R A Q I++GD I+ YG LV + L A Sbjct: 243 NTPEDEAKEGLLEWIDFLINERITLAEYVIARNAAQSINDGDTIVTYGRHRLVEKTLLRA 302 Query: 350 WTEGRRFRVVVVDSRPWLEGRHTLRSLVHAGVPASYL-LIPAASYVLPEVSKVLLGAHAL 408 EG+ F V V+D EG+ + L HAG+P Y + +P S V LG A+ Sbjct: 303 RKEGKSFNVTVLDDPYVGEGKELAKVLRHAGIPVLYSPNLGGLRSKVPAASNVFLGGEAI 362 Query: 409 LANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFC-ERVQTDAFVSNELD-DPDDLQCK 466 ANGS+ + GTA +A+ A V+V CET F ERV DA NE+D + + C Sbjct: 363 FANGSLHAPSGTADVAMAATNAGAKVIVLCETINFDRERVSVDALTYNEIDPERNTGDCF 422 Query: 467 RGEHVALANWQNHASLRLLNLVYDVTPPELVDLVITEL----GMIPCSSVPVVLR 517 R L++D T + VITE+ G P ++ +LR Sbjct: 423 R-------------------LLFDNTHERYITGVITEIEFGGGNSPAQAILALLR 458 >6I7T-C nrPDB Length = 651 Score = 345 bits (885), Expect = 3e-95, Method: Composition-based stats. Identities = 141/384 (36%), Positives = 199/384 (51%), Gaps = 62/384 (16%) Query: 200 SSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDYTTPPNEELSRDLVNKLKPY 259 +IHP+++ L + + GS RCIA+L Q VI+DY TP LSR+L + L Sbjct: 267 KDLIHPSILLLTSHLAHYKIVGSIPRCIAMLEVFQIVIKDYQTPKGTTLSRNLTSYLSHQ 326 Query: 260 MSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSELRAAIDRYVQEKIVLAAQAI 319 + L + RPLS +M NAI++L +EI+ + S ++ AK +L I ++ +EKI LA Q I Sbjct: 327 IDLLKKARPLSVTMGNAIRWLKQEISLIDPSTPDKAAKKDLCEKIGQFAKEKIELADQLI 386 Query: 320 SRFAYQKISNGDVILVYGCSSLVSRILQE-AWTEGRRFRVVVVDSRPWLEGRHTLRSLVH 378 A +I I+ YG S +++ +L A + + +V+VVDSRP EGR +L + Sbjct: 387 IDNASTQIEESTTIVTYGSSKVLTELLLHNAISLKKNIKVIVVDSRPLFEGRKMAETLRN 446 Query: 379 AGVPASYLLIPAASYVLPE-VSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVC 437 AGV Y LI + + V V LGAH++L+NG + SR GTA LA+ A+ N+PVLVC Sbjct: 447 AGVNVMYALITSLDTIFNMDVDYVFLGAHSILSNGFLYSRAGTAMLAMSAKRRNIPVLVC 506 Query: 438 CETYKFCERVQTDAFVSNELDDPDDLQC--------KRGEHVALAN-------------- 475 CE+ KF +RVQ D+ NEL DP+DL +RG AL N Sbjct: 507 CESLKFSQRVQLDSVTFNELADPNDLVNIDYENPVERRGNKGALLNQFIKERKFEKKKLA 566 Query: 476 -------------------------------------WQNHASLRLLNLVYDVTPPELVD 498 WQ SL ++N++YD+TPPE + Sbjct: 567 MENKPKGNKIGGKKGSEGESKDASNEEDSNSKNILDGWQELPSLNIVNILYDLTPPEYIK 626 Query: 499 LVITELGMIPCSSVPVVLR-VKSS 521 VITE G +P SSVPV+LR K S Sbjct: 627 KVITEFGALPPSSVPVILREYKGS 650 >3A9C-A nrPDB Length = 338 Score = 321 bits (822), Expect = 4e-88, Method: Composition-based stats. Identities = 87/318 (27%), Positives = 159/318 (50%), Gaps = 16/318 (5%) Query: 207 MVRLGLQYSQGLVSGSNARCIALLRALQQVIQDYTTPPNEELSRDLVNKLKPYMSFLTQC 266 ++ + + + G+ + ALQ + +E ++K L + Sbjct: 23 VLEIAEKIKNMEIRGAGKIARSAAYALQLQAEKSKATNVDE----FWKEMKQAAKILFET 78 Query: 267 RPLSASMHNAIKFLNKEITSVGSSKREEEAKSELRAAIDRYVQEKIVLAAQA---ISRFA 323 RP + S+ NA++++ SS + E +LR I +E I + +A I F Sbjct: 79 RPTAVSLPNALRYVMHRGKIAYSSGADLE---QLRFVIINAAKEFIHNSEKALERIGEFG 135 Query: 324 YQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVVVDSRPWLEGRHTLRSLVHAGVPA 383 ++I +GDVI+ + S +++ AW +G+ +V+V ++RP +G+ T + L G+P Sbjct: 136 AKRIEDGDVIMTHCHSKAAISVMKTAWEQGKDIKVIVTETRPKWQGKITAKELASYGIPV 195 Query: 384 SYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKF 443 Y++ AA + + KV++GA ++ NG+V++++GTA +AL A+ H V ++ ETYKF Sbjct: 196 IYVVDSAARHYMKMTDKVVMGADSITVNGAVINKIGTALIALTAKEHRVWTMIAAETYKF 255 Query: 444 CERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHASLRLLNLVYDVTPPELVDLVITE 503 V E+ DP ++ + L W ++ + N +DVTPPE VD++ITE Sbjct: 256 HPETMLGQLVEIEMRDPTEVIPED----ELKTWP--KNIEVWNPAFDVTPPEYVDVIITE 309 Query: 504 LGMIPCSSVPVVLRVKSS 521 G+IP + +LR + Sbjct: 310 RGIIPPYAAIDILREEFG 327 >5YG5-A nrPDB Length = 324 Score = 309 bits (790), Expect = 2e-84, Method: Composition-based stats. Identities = 76/274 (27%), Positives = 149/274 (54%), Gaps = 10/274 (3%) Query: 250 RDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITS--VGSSKREEEAKSELRAAIDRY 307 +L N+LK L RP + S+ NA++++ + + +G + E + + +A + Sbjct: 48 EELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAYLGGADLETLRFTAINSAKEFI 107 Query: 308 VQEKIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVVVDSRPWL 367 + A + I ++I +GD+I+ + S ++++A+ +G+ +V+V ++RP Sbjct: 108 YNSE--KAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNIKVIVTETRPKW 165 Query: 368 EGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVA 427 +G+ T + L G+P Y++ AA + + KV++GA ++ ANG+V++++GT+ +AL A Sbjct: 166 QGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVINKIGTSLIALTA 225 Query: 428 RAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHASLRLLNL 487 + H V V++ ETYKF V E+ DP ++ + L W ++ + N Sbjct: 226 KEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEE----ELRTWP--KNIEVWNP 279 Query: 488 VYDVTPPELVDLVITELGMIPCSSVPVVLRVKSS 521 +DVTPPE +D++ITE G+IP + +L+ + Sbjct: 280 AFDVTPPEYIDVIITERGIIPPYAAIDILKEEFG 313 >2YRF-A nrPDB Length = 374 Score = 272 bits (696), Expect = 2e-73, Method: Composition-based stats. Identities = 74/309 (23%), Positives = 137/309 (44%), Gaps = 31/309 (10%) Query: 214 YSQGLVSGSNARCIALLRALQQVIQDYTTPPNEELSRDLVNKLKPYMSFLTQCRPLSASM 273 V G+ A I L +D T E R +L+ +L RP + ++ Sbjct: 66 IVTLKVRGAPAIGITAAFGLALAAKDIETDNVTEFRR----RLEDIKQYLNSSRPTAINL 121 Query: 274 HNAIKFLNKEITSVGSSKREEEAKSEL-RAAIDRYVQEKIVLAAQAISRFAYQKISNGDV 332 A++ L+ SV ++ EAK+ L AI V+++ + I + A Q GD Sbjct: 122 SWALERLSH---SVENAISVNEAKTNLVHEAIQIQVEDE--ETCRLIGQNALQLFKKGDR 176 Query: 333 ILVYGC----------SSLVSRILQEAWTEGRRFRVVVVDSRPWLEG-RHTLRSLVHAGV 381 I+ ++L L + G + ++RP L+G R T L+ G+ Sbjct: 177 IMTICNAGSIATSRYGTALAPFYLAKQKDLG--LHIYACETRPVLQGSRLTAWELMQGGI 234 Query: 382 PASYLLIPAASYVLPE--VSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCE 439 + + A++ + E +S V++GA + NG +++GT LA++A A ++P V Sbjct: 235 DVTLITDSMAAHTMKEKQISAVIVGADRIAKNGDTANKIGTYGLAILANAFDIPFFVAAP 294 Query: 440 TYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHASLRLLNLVYDVTPPELVDL 499 F +V+ A + E DP++++ G A +++ + N +D+TP +L+ Sbjct: 295 LSTFDTKVKCGADIPIEERDPEEVRQISGVRTA------PSNVPVFNPAFDITPHDLISG 348 Query: 500 VITELGMIP 508 +ITE G++ Sbjct: 349 IITEKGIMT 357 >2A0U-A nrPDB Length = 383 Score = 272 bits (694), Expect = 3e-73, Method: Composition-based stats. Identities = 77/318 (24%), Positives = 139/318 (43%), Gaps = 26/318 (8%) Query: 218 LVSGSNARCIALLRALQQVIQDYTTPPNEEL--SRDLVNKLKPYMSFLTQCRPLSASMHN 275 V G+ A IA+ AL + N EL R++ L F+ RP + ++ N Sbjct: 59 RVRGAPA--IAVSAALGIAVATQRKAANGELKSGREVQTFLLTSCDFVMTSRPTAVNLFN 116 Query: 276 AIKFLNKEITSVGSSKREEE---AKSELRAAI---DRYVQEKIVLAAQAISRFAYQKISN 329 ++ L ++ + +K E A EL A+ D E I+ A A + Sbjct: 117 CLRDLKAQVDKLDPTKAAAEVAQAFVELAEAVYTNDVAFNEGIMRHGAAHILAAAKAEGR 176 Query: 330 GDVILVYGCSS---------LVSRILQEAWTEGRRFRVVVVDSRPWLEG-RHTLRSLVHA 379 V ++ C++ ++++ + +G+ RV ++RPW +G R T+ V Sbjct: 177 DKVSILTICNTGALATSRYGTALGVVRQLFYDGKLERVYACETRPWNQGARLTVYECVQE 236 Query: 380 GVPASYLLIPAASYVL--PEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVC 437 +P + + AAS ++ ++ V++GA + NG +++GT LA+ A+ H V + V Sbjct: 237 DIPCTLICDGAASSLMLNRKIDAVVVGADRICQNGDTANKIGTYNLAVSAKFHGVKLYVA 296 Query: 438 CETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHASLRLLNLVYDVTPPELV 497 T + + V E +P ++ + H L + N V+D+TP EL+ Sbjct: 297 APTTTLDVKTASGNHVEIEEREPTEITTNLVTKQRVVADGPH--LSIWNPVFDITPSELI 354 Query: 498 D-LVITELGM-IPCSSVP 513 +ITE G+ P +S P Sbjct: 355 TGGIITEKGVQAPAASAP 372 >1T9K-A nrPDB Length = 347 Score = 270 bits (689), Expect = 1e-72, Method: Composition-based stats. Identities = 68/316 (21%), Positives = 134/316 (42%), Gaps = 31/316 (9%) Query: 219 VSGSNARCIALLRALQQVIQDYTTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIK 278 V G+ A +A ++DY T L + +K L + RP + ++ A+ Sbjct: 49 VRGAPAIGVAAAFGYVLGLRDYKTGS-------LTDWMKQVKETLARTRPTAVNLFWAL- 100 Query: 279 FLNKEITSVGSSKREEEAKSELRAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGC 338 + V + E E+ + + + +AI + Q I +G IL + Sbjct: 101 ---NRMEKVFFENADRENLFEILENEALKMAYEDIEVNKAIGKNGAQLIKDGSTILTHCN 157 Query: 339 SS--------LVSRILQEAWTEGRRFRVVVVDSRPWLEG-RHTLRSLVHAGVPASYLLIP 389 + +++ A G+R RV ++RP+L+G R T L+ G+ + Sbjct: 158 AGALATVDYGTALGVIRAAVESGKRIRVFADETRPYLQGARLTAWELMKDGIEVYVITDN 217 Query: 390 AASYVLPE--VSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERV 447 A +++ + V++GA + NG +++GT LA++A+ +N+P V + Sbjct: 218 MAGWLMKRGLIDAVVVGADRIALNGDTANKIGTYSLAVLAKRNNIPFYVAAPVSTIDPTI 277 Query: 448 QTDAFVSNELDDPDDLQCKRGEHVALANWQNHASLRLLNLVYDVTPPELVDLVITELGMI 507 ++ + E P+++ G +A +++LN +DVT L+ +ITE G+I Sbjct: 278 RSGEEIPIEERRPEEVTHCGGNRIA------PEGVKVLNPAFDVTENTLITAIITEKGVI 331 Query: 508 PC---SSVPVVLRVKS 520 ++ +L V S Sbjct: 332 RPPFEENIKKILEVGS 347 >1T5O-A nrPDB Length = 351 Score = 260 bits (664), Expect = 1e-69, Method: Composition-based stats. Identities = 75/319 (23%), Positives = 139/319 (43%), Gaps = 32/319 (10%) Query: 218 LVSGSNARCIALLRALQQVIQDYTTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAI 277 V G+ A A + ++ +EL LK FL RP + ++ I Sbjct: 43 AVRGAPALEAAGAYGIALAAREREFADVDELKEH----LKKAADFLASTRPTAVNLFVGI 98 Query: 278 KFLNKEITSVGSSKREEEAKSELRAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYG 337 + ++ EE + LR A + E+ V + + + + + +GDV+L Y Sbjct: 99 E--RALNAALKGESVEEVKELALREA--EKLAEEDVERNRKMGEYGAELLEDGDVVLTYC 154 Query: 338 CSS--------LVSRILQEAWTEGRRFRVVVVDSRPWLEG-RHTLRSLVHAGVPASYLLI 388 + +++ A +G+ RV+ ++RP +G R T L+ G+ + + Sbjct: 155 NAGRLATVDWGTALGVVRSAVEQGKEIRVIACETRPLNQGSRLTCWELMEDGIDVTLITD 214 Query: 389 PAASYVLPE--VSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFC-E 445 V+ + V KV++GA ++ + +V +++GT +++VA+ HN+P V F E Sbjct: 215 SMVGIVMQKGMVDKVIVGADRIVRD-AVFNKIGTYTVSVVAKHHNIPFYVAAPKATFDWE 273 Query: 446 RVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHASLRLLNLVYDVTPPELVDLVITELG 505 R D V E ++L +A ++++ N +D TP E V +ITE G Sbjct: 274 RTAKD--VVIEERPREELIFCGKRQIAPL------NVKVYNPAFDPTPLENVTALITEYG 325 Query: 506 MI-PCS--SVPVVLRVKSS 521 +I P +VP VL+ + Sbjct: 326 VIYPPYEVNVPKVLKFEGG 344 >5B04-A nrPDB Length = 341 Score = 245 bits (626), Expect = 2e-65, Method: Composition-based stats. Identities = 83/298 (27%), Positives = 130/298 (43%), Gaps = 17/298 (5%) Query: 227 IALLRALQQVIQDYTTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITS 286 +A + AL Q++ E L N + LSA +F+ + + Sbjct: 37 VAAIEALVQLLSRSQAKTISEFMDILQNGSNTLKEGVQNNISLSAGCDIFQRFVTRSLHD 96 Query: 287 VGSSKREEEAKSELRAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRIL 346 VG E+ K L ++Q + Q I+ Y I +G VIL +G S V+ +L Sbjct: 97 VG---DFEQCKRHLVENGKLFIQ-RARACRQRIAHLGYPLIRDGSVILTHGFSRGVAAVL 152 Query: 347 QEAWTEGRRFRVVVVDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAH 406 A RF+V V +SRP G R+L +A +P +L A S+ + V VL+GA Sbjct: 153 LAAAKRHVRFKVFVTESRPSGSGCLMTRTLKNACIPTCMVLDSAVSFTMNRVDLVLVGAE 212 Query: 407 ALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAF------VSNELDDP 460 ++ NG +++++GT QLA+ A+ + P E++KF + E DDP Sbjct: 213 GVVENGGLINQIGTFQLAVFAKHAHKPFYAVAESHKFVRMFPLSQYDIPFSRPILEFDDP 272 Query: 461 D-DLQCKRGEHVALANWQNHASLRL------LNLVYDVTPPELVDLVITELGMIPCSS 511 + E + + H L + N DVTPPE V +IT+LG+I S Sbjct: 273 SPETVHPEPEPIPTPSDAIHNELIMNEEQIRNNPTLDVTPPEFVSGLITDLGIIDSKS 330 >1VB5-A nrPDB Length = 276 Score = 236 bits (601), Expect = 2e-62, Method: Composition-based stats. Identities = 69/307 (22%), Positives = 137/307 (44%), Gaps = 38/307 (12%) Query: 207 MVRLGLQYSQGLVSGSNARCIALLRALQQVIQDYTTPPNEELSRDLVNKLKPYMSFLTQC 266 ++ + + + + G++ A + ++ +E L D + +L+ + + Sbjct: 6 VLEILREMKRERIKGASWLAKKGAEAFLTLAEEL----DESLLEDAIMELREE---VVKV 58 Query: 267 RPLSASMHNAIKFLNKEITSVGSSKREEEAKSELRAAIDRYVQEKIVLAAQAISRFAYQK 326 P AS++N +F+ + L++ +++ ++ A + ++ Q Sbjct: 59 NPSMASLYNLARFI-----------PVTNRRDILKSRALEFLR-RMEEAKRELASIGAQL 106 Query: 327 ISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVVVDSRPWLEGRHTLRSLVHAGVPASYL 386 I +GDVI+ + SS V I++ A +RF+V++ +S P EG H R L +G+ + Sbjct: 107 IDDGDVIITHSFSSTVLEIIRTAKERKKRFKVILTESSPDYEGLHLARELEFSGIEFEVI 166 Query: 387 LIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCER 446 E S ++GA + +G V+++ GT LAL + +P V ETYKF Sbjct: 167 TDAQMGLFCREASIAIVGADMITKDGYVVNKAGTYLLALACHENAIPFYVAAETYKFHPT 226 Query: 447 VQTDAFVSNELDDPDDLQCKRGEHVALANWQNHASLRLLNLVYDVTPPELVDLVITELG- 505 +++ + E D ++R+ N+++DVTP + V +ITELG Sbjct: 227 LKSGDVMLMERD------------------LIRGNVRIRNVLFDVTPWKYVRGIITELGI 268 Query: 506 MIPCSSV 512 +IP + Sbjct: 269 VIPPRDI 275 >6O85-G nrPDB Length = 305 Score = 232 bits (590), Expect = 4e-61, Method: Composition-based stats. Identities = 71/290 (24%), Positives = 138/290 (47%), Gaps = 12/290 (4%) Query: 228 ALLRALQQVIQDYTTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSV 287 + + A++ +++ E + + L L + L S ++ + + + I+ Sbjct: 22 SAVAAIRTLLEFLKRDKGETI-QGLRANLTSAIETLCGVD-SSVAVSSGGELFLRFISLA 79 Query: 288 GSSKRE-EEAKSELRAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRIL 346 + + K + + +++ +I L+ I+ + I +G IL + S +V R+L Sbjct: 80 SLEYSDYSKCKKIMIERGELFLR-RISLSRNKIADLCHTFIKDGATILTHAYSRVVLRVL 138 Query: 347 QEAWTEGRRFRVVVVDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAH 406 + A +RF V V +S+P L G+ ++L H VP + +L A Y++ + V++GA Sbjct: 139 EAAVAAKKRFSVYVTESQPDLSGKKMAKALCHLNVPVTVVLDAAVGYIMEKADLVIVGAE 198 Query: 407 ALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCK 466 ++ NG +++++GT Q+A+ A+A N P V E++KF N+ D PD + K Sbjct: 199 GVVENGGIINKIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPL-----NQQDVPDKFKYK 253 Query: 467 RGEHVALANWQNHASLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVL 516 L Q L+ + D T P L+ L+ T+LG++ S+V L Sbjct: 254 AD---TLKVAQTGQDLKEEHPWVDYTAPSLITLLFTDLGVLTPSAVSDEL 300 >4LDQ-A nrPDB Length = 369 Score = 232 bits (590), Expect = 4e-61, Method: Composition-based stats. Identities = 74/323 (22%), Positives = 137/323 (42%), Gaps = 49/323 (15%) Query: 218 LVSGSNARCIALLRALQQVIQDYTTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAI 277 V G+ A IAL+ L ++ LV ++ +SFL RP + +M A Sbjct: 44 KVRGAPA--IALVGCLSLAVE-LQAGAGGPGLAALVAFVRDKLSFLVTARPTAVNMARAA 100 Query: 278 KFLNKEITSVGSSKREEEAKSELRAAIDRYVQEKIVLA-----------AQAISRFAYQK 326 + ++ V + + E E +E V+E+++ ++I + Sbjct: 101 R----DLADVAAREAEREGATE------EAVRERVICCTEDMLEKDLRDNRSIGDLGARH 150 Query: 327 I------SNGDVILVYGCSS---------LVSRILQEAWTEGRRFRVVVVDSRPWLEG-R 370 + S G V ++ C++ +++ + GR ++RP+ +G R Sbjct: 151 LLERVAPSGGKVTVLTHCNTGALATAGYGTALGVIRSLHSLGRLEHAFCTETRPYNQGAR 210 Query: 371 HTLRSLVHAGVPASYLLIPAASYVL--PEVSKVLLGAHALLANGSVMSRVGTAQLALVAR 428 T LV+ +PA+ + + + VS V++GA ++ANG ++VGT QLA+VA+ Sbjct: 211 LTAFELVYEQIPATLITDSMVAAAMAHRGVSAVVVGADRVVANGDTANKVGTYQLAIVAK 270 Query: 429 AHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHASLRLLNLV 488 H +P V + R++T + E +L G +A + + N Sbjct: 271 HHGIPFYVAAPSSSCDLRLETGKEIIIEERPGQELTDVNGVRIA------APGIGVWNPA 324 Query: 489 YDVTPPELVD-LVITELGMIPCS 510 +DVTP +L+ +ITELG+ Sbjct: 325 FDVTPHDLITGGIITELGVFAPE 347 >6O81-C nrPDB Length = 368 Score = 230 bits (586), Expect = 1e-60, Method: Composition-based stats. Identities = 75/325 (23%), Positives = 140/325 (43%), Gaps = 41/325 (12%) Query: 220 SGSNARCIALLRALQQVIQDYTTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKF 279 S L L+Q+I D+ EL ++ +T +P ++ N ++ Sbjct: 46 RSSEEMARETLGLLRQIITDHRWSNAGELME----LIRREGRRMTAAQPSETTVGNMVRR 101 Query: 280 ------------------------LNKEITSVGSSKREEEAKSELRAAIDRYVQEKIVLA 315 L+K +TS G ++ ++L++ I + E +V Sbjct: 102 VLKIIREEYGRLHGRSDESDQQESLHKLLTSGGLNEDFSFHYAQLQSNIIEAINELLVEL 161 Query: 316 A---QAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVVVDSRPWLEGRHT 372 + I+ A + I + +VI+ G S V L+EA R+F V+V + P+ +G Sbjct: 162 EGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKEA-ARKRKFHVIVAECAPFCQGHEM 220 Query: 373 LRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNV 432 +L AG+ + + A V+ V+KV++G +LANG++ + GT LAL A+ H+ Sbjct: 221 AVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTILANGALRAVTGTHTLALAAKHHST 280 Query: 433 PVLVCCETYKFCERVQTDAFVSNELDDPDDL-QCKRGEHVALANWQNHASLRLLNLVYDV 491 P++VC +K + + ++ P+++ G+ L H V+D Sbjct: 281 PLIVCAPMFKLSPQFPNEEDSFHKFVAPEEVLPFTEGD--ILEKVSVHC------PVFDY 332 Query: 492 TPPELVDLVITELGMIPCSSVPVVL 516 PPEL+ L I+ +G S + ++ Sbjct: 333 VPPELITLFISNIGGNAPSYIYRLM 357 >6A34-A nrPDB Length = 364 Score = 224 bits (571), Expect = 5e-59, Method: Composition-based stats. Identities = 50/272 (18%), Positives = 118/272 (43%), Gaps = 22/272 (8%) Query: 250 RDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSELRAAIDRYVQ 309 + ++ + L RP + ++ A+ + K + +E + ++ A + Sbjct: 83 EEFLDGFEKAYEILKNTRPTAVNLFWALNRIKKLVEEHSEDPLDEIKRLIVQEA--YKIA 140 Query: 310 EKIVLAAQAISRFAYQKISNGDVILVYG--------CSSLVSRILQEAWTEGRRFRVVVV 361 ++ V A + + + + G+ IL + V +++ +G + + Sbjct: 141 DEDVEANLRMGHYGAEVLPEGN-ILTHCNAGSLATVHLGTVGSVVRVMHKDGSLKLLWLD 199 Query: 362 DSRPWLEG-RHTLRSLVHAGVPASYLLIPAASYVLPE--VSKVLLGAHALLANGSVMSRV 418 ++RP L+G R + + G+ + AA++V+ + V +++GA ++ANG +++ Sbjct: 200 ETRPVLQGARLSAWEYSYDGLNVKLIADNAAAFVMQQGFVDAIIVGADRIVANGDFANKI 259 Query: 419 GTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQN 478 GT LA++AR H +P +++ + E P+++ G +A Sbjct: 260 GTYMLAVLAREHGIPFFAVAPLSSIDMELKSGKDIPIEERSPEEVLTCGGCRIA------ 313 Query: 479 HASLRLLNLVYDVTPPELVDLVITELGMI-PC 509 + + N +DVTP + + +IT+ G++ P Sbjct: 314 -PDVPVYNPAFDVTPHKYLTGIITDRGVVWPP 344 >6I3M-A nrPDB Length = 305 Score = 219 bits (558), Expect = 2e-57, Method: Composition-based stats. Identities = 71/290 (24%), Positives = 125/290 (43%), Gaps = 22/290 (7%) Query: 227 IALLRALQQVIQDYTTPPNEELSRDLVNKLKPYMSFLTQCRPLSASM----HNAIKFLNK 282 IA + AL +++ TP E + +++N +K L + P S S+ ++F+ + Sbjct: 24 IAAIEALVTLLR-IKTP---ETAAEMINTIKSSTEELIKSIPNSVSLRAGCDIFMRFVLR 79 Query: 283 EITSVGSSKREEEAKSELRAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCSSLV 342 + G E K L +V + + I+ I++ D+ILV+G S V Sbjct: 80 NLHLYG---DWENCKQHLIENGQLFVS-RAKKSRNKIAEIGVDFIADDDIILVHGYSRAV 135 Query: 343 SRILQEAWTEGRRFRVVVVDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVL 402 +L A + RFR VV +SRP +G L G+P + ++ A V+ +V KV Sbjct: 136 FSLLNHAANKFIRFRCVVTESRPSKQGNQLYTLLEQKGIPVTLIVDSAVGAVIDKVDKVF 195 Query: 403 LGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDD 462 +GA + +G +++ VGT + ++A P V E++KF + P D Sbjct: 196 VGAEGVAESGGIINLVGTYSVGVLAHNARKPFYVVTESHKFVRMFPLSSDDLPMAGPPLD 255 Query: 463 LQCKRGEHVALANWQNHASLRLLNLVYDVTPPELVDLVITELGMIPCSSV 512 + + L D T E + +IT+LG++ S+V Sbjct: 256 FTRRTDDL----------EDALRGPTIDYTAQEYITALITDLGVLTPSAV 295 >6JLZ-C nrPDB Length = 399 Score = 205 bits (520), Expect = 5e-53, Method: Composition-based stats. Identities = 73/269 (27%), Positives = 121/269 (44%), Gaps = 21/269 (7%) Query: 261 SFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKS------ELRAAIDRYVQEKIVL 314 + P+S M++++ L T + + S ++RA I +Q+ I Sbjct: 130 KLVQSHEPVSVQMYSSMLNLLGRPTLESPTHSKTVGDSRVTGGMDMRAVIISGIQDVIDE 189 Query: 315 AAQAISRFAYQ---KISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVVVDSRPWLE-GR 370 + + Q + + ++IL GCS V L+ A + R+F V+V + P + G Sbjct: 190 LDKINTDIEVQSMDHLHSNEIILTQGCSKTVEAFLRFA-AKKRKFSVIVAEGFPNNQKGS 248 Query: 371 H-TLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARA 429 H + L AG+ + + ++ V+KV+LG HA+L NG +++ G +A AR Sbjct: 249 HAMAKRLAQAGIDTTVISDATIFAIMSRVNKVILGTHAILGNGGLVTYSGAQLVAQAARH 308 Query: 430 HNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQ-CKRGEHVALANWQNHASLRLLNLV 488 H PV+VC YK D +L PD + G+ ++ A +LN Sbjct: 309 HATPVVVCSGIYKLSPVYPYDLESIIQLSSPDKIMSFNEGDLISRA--------EILNPY 360 Query: 489 YDVTPPELVDLVITELGMIPCSSVPVVLR 517 YD PP+LVDL IT LG P S + ++ Sbjct: 361 YDYIPPDLVDLFITNLGGYPPSYLYRIMN 389 Score = 31.8 bits (70), Expect = 0.81, Method: Composition-based stats. Identities = 35/206 (16%), Positives = 70/206 (33%), Gaps = 22/206 (10%) Query: 197 SIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDYTTPPNEELSRDLVNKL 256 +I +PA+ L V G A + ++QVI ++L ++ + Sbjct: 9 TINVEHTYPAVSSLIADLKSRKVQGPFAVAVETALVMRQVISQTRWSTVDQL----IDTV 64 Query: 257 KPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSELRAAIDRYVQEKIVLAA 316 + S L + +P S N + E EL D EK+++++ Sbjct: 65 RAVGSTLVKAQPTEFSCGN---------IIRRILRLIREEYQELLKTADE--NEKLIVSS 113 Query: 317 QAISRFAYQK-ISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVVVDSRPWLEGRHTLRS 375 S + ++ I + + ++ V GR S+ + R T Sbjct: 114 SNSSSPSQKRDIPSNEKLVQSHEPVSVQMYSSMLNLLGRPTLESPTHSKTVGDSRVT--- 170 Query: 376 LVHAGVPASYLLIPAASYVLPEVSKV 401 G+ ++I V+ E+ K+ Sbjct: 171 ---GGMDMRAVIISGIQDVIDELDKI 193 >6I3M-E nrPDB Length = 381 Score = 142 bits (358), Expect = 3e-34, Method: Composition-based stats. Identities = 67/371 (18%), Positives = 123/371 (33%), Gaps = 60/371 (16%) Query: 187 SRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDYTTPPNE 246 S Q + + +S ++ + + + V GS A + L+ L + I Sbjct: 2 SSQAFTSVHPNAATSDVNVTIDTFVAKLKRRQVQGSYAIALETLQLLMRFISAARWNHVN 61 Query: 247 ELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFL-------------------------- 280 DL+ +++ + L + P + S N I+ + Sbjct: 62 ----DLIEQIRDLGNSLEKAHPTAFSCGNVIRRILAVLRDEVEEDTMSTTVTSTSVAEPL 117 Query: 281 ----------------NKEITSVGSSKREEEAKSELRAAIDRYVQEKIVLAAQAISRFAY 324 N++ +S SS + + ++ + + ++I + I + A Sbjct: 118 ISSMFNLLQKPEQPHQNRKNSSGSSSMKTKTDYRQVAIQGIKDLIDEIKNIDEGIQQIAI 177 Query: 325 QKISNGDVILV-YGCSSLVSRILQEAWTEG-RRFRVVVVDSRPWL--EGRHTLRSLVHAG 380 I + +++L S V + L A R F V+V + P + L Sbjct: 178 DLIHDHEILLTPTPDSKTVLKFLITARERSNRTFTVLVTEGFPNNTKNAHEFAKKLAQHN 237 Query: 381 VPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSR-VGTAQLALVARAHNVPVLVCCE 439 + + A ++ V KV++G A+ NG +S G + + AR PV Sbjct: 238 IETLVVPDSAVFALMSRVGKVIIGTKAVFVNGGTISSNSGVSSVCECAREFRTPVFAVAG 297 Query: 440 TYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHASLRLLNLVYDVTPPELVDL 499 YK D E G L L +N + D PPE +D+ Sbjct: 298 LYKLSPLYPFDVEKFVEF---------GGSQRILPRMDPRKRLDTVNQITDYVPPENIDI 348 Query: 500 VITELGMIPCS 510 IT +G S Sbjct: 349 YITNVGGFNPS 359 >6BYS-B nrPDB Length = 379 Score = 39.1 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 32/119 (26%), Positives = 47/119 (39%), Gaps = 6/119 (5%) Query: 77 LPESGIQLGTPREKVPAG--RSKAELRAERRAKQ--EAERALKQARKGEQGGPPPKASPS 132 L +S +QL T R + P R E + AKQ ++A +A E PP +P Sbjct: 29 LKDSIVQLCTARPERPMAFLREYFEKLEKEEAKQIQNLQKAGSRADSREDEISPPPPNPV 88 Query: 133 TAGETPSGVKRLPEYPQVDDL-LLRRLVKKPERQQVPTRKDYGSKVSLFSHLPQYSRQN 190 G G Y + D +R+++ K + K V LFSHL R + Sbjct: 89 VKGRRRRGAISAEVYTEEDAASYVRKVIPKDYKTMAALAKAIEKNV-LFSHLDDNERSD 146 >5A1W-H nrPDB Length = 511 Score = 36.8 bits (83), Expect = 0.024, Method: Composition-based stats. Identities = 31/129 (24%), Positives = 51/129 (39%), Gaps = 21/129 (16%) Query: 26 AVGREMTKEEKLQLRKEKKQ-QKKKRKEEKGAEPETG------SAVSAAQCQVGPTRELP 78 AV +E K ++R++ K+ Q+ +R E+ + G SAVS T + Sbjct: 146 AVRETQEREAKAEMRRKAKELQQARRDAERQGKKAPGFGGFGSSAVSGGSTAAMITETII 205 Query: 79 ESGIQLGTPREKVPAGRSKA-ELRAERRA--------KQEAERAL-----KQARKGEQGG 124 E+ P P+G SKA +L A+ + K E E + K+ + + Sbjct: 206 ETDKPKVAPAPARPSGPSKALKLGAKGKEVDNFVDKLKSEGETIMSSNMGKRTSEATKVH 265 Query: 125 PPPKASPST 133 PP S Sbjct: 266 APPINMESV 274 >2WHD-A nrPDB Length = 351 Score = 34.1 bits (76), Expect = 0.16, Method: Composition-based stats. Identities = 11/58 (18%), Positives = 24/58 (41%), Gaps = 3/58 (5%) Query: 364 RPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTA 421 R + G T + G+ A + AA + V+ G + + G+ +++ G+ Sbjct: 148 RLYFSGSDTYW---NRGISACAVCDGAAPIFRNKPIAVIGGGDSAMEEGNFLTKYGSQ 202 >3RQF-A nrPDB Length = 214 Score = 33.3 bits (74), Expect = 0.24, Method: Composition-based stats. Identities = 20/144 (13%), Positives = 49/144 (34%), Gaps = 8/144 (5%) Query: 238 QDYTTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAK 297 + E L R + ++ YM + + P ++ + L + ++ + + Sbjct: 72 KSVEVNFTESLLRMAADDVEEYM--IERPEPEFQDLNEKARALKQILSKIPDEINDRVRF 129 Query: 298 SELRAAIDRYVQEKIVLAAQAISRFAYQ----KISNGDVILVYGCSSLVSRILQEAWTEG 353 + I ++E + ++ YQ + Y S S L+ + +G Sbjct: 130 LQTIKDIASAIKELLDTVNNVFKKYQYQNRRALEHQKKEFVKY--SKSFSDTLKTYFKDG 187 Query: 354 RRFRVVVVDSRPWLEGRHTLRSLV 377 + V V +R + L++ Sbjct: 188 KAINVFVSANRLIHQTNLILQTFK 211 >6FYY-r nrPDB Length = 274 Score = 33.3 bits (74), Expect = 0.28, Method: Composition-based stats. Identities = 34/146 (23%), Positives = 61/146 (41%), Gaps = 13/146 (8%) Query: 21 PPGPGAVGREMTKEEKLQLRKEKKQQKKKR-KEEKGAEPETGSAVSAAQCQVGPTRELPE 79 P GP AV + +E +L+L + KQ +++R ++EK + +TG QC R Sbjct: 65 PAGPSAVTARLGEEVELRLSRNWKQAEEERIQKEKASLTKTG-----LQC-----RLCGN 114 Query: 80 SGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARKGEQGGPPPKASPST--AGET 137 + + P + + + S E A EA K + G G P + P + AG Sbjct: 115 DHMTMNCPFKTILSELSALEDPATSEGGVEAASEEKAGQVGGAGSIPGQYVPPSRRAGAR 174 Query: 138 PSGVKRLPEYPQVDDLLLRRLVKKPE 163 + + DD+ ++++ E Sbjct: 175 DPSSDAYRDSRERDDMCTLKIMQVNE 200 >3D8X-A nrPDB Length = 326 Score = 32.9 bits (73), Expect = 0.30, Method: Composition-based stats. Identities = 14/90 (15%), Positives = 26/90 (28%), Gaps = 12/90 (13%) Query: 341 LVSRILQEAWTEGRRFRVVVVDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSK 400 I+ +R L G T G+ A + A + Sbjct: 118 TTDAIILATGASAKRMH---------LPGEETYW---QKGISACAVCDGAVPIFRNKPLA 165 Query: 401 VLLGAHALLANGSVMSRVGTAQLALVARAH 430 V+ G + +++ G+ LV + H Sbjct: 166 VIGGGDSACEEAQFLTKYGSKVFMLVRKDH 195 >2JGP-A nrPDB Length = 520 Score = 32.6 bits (72), Expect = 0.45, Method: Composition-based stats. Identities = 33/179 (18%), Positives = 66/179 (36%), Gaps = 14/179 (7%) Query: 152 DLLLRRLVKKPERQQVPTRKDYGSKVSLFSHLPQ-----------YSRQNSLTQFMSIPS 200 D+ LR L +KP Q++ + +K ++FS P R L QF + Sbjct: 58 DIPLRILFEKPTIQELAAFIEETAKGNVFSIEPVQKQAYYPVSSAQKRMYILDQFEGVGI 117 Query: 201 SVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDYTTPPNEELSRDLVNKLKPYM 260 S P+ + + + + V + R IA +L+ P + + D+ L Sbjct: 118 SYNMPSTMLIEGKLERTRVEAAFQRLIARHESLRTSFAVVNGEPVQNIHEDVPFALAYSE 177 Query: 261 SFLTQCRPLSASM---HNAIKFLNKEITSVGSSKREEEAKSELRAAIDRYVQEKIVLAA 316 + R L +S+ + ++ + + +++ +I V I+LA Sbjct: 178 VTEEEARELVSSLVQPFDLEVAPLIRVSLLKIGEDRYVLFTDMHHSISDGVSSGILLAE 236 >4IOV-A nrPDB Length = 733 Score = 32.2 bits (71), Expect = 0.54, Method: Composition-based stats. Identities = 24/108 (22%), Positives = 44/108 (40%), Gaps = 4/108 (3%) Query: 47 KKKRKEEKGAEPETGSAVSAAQCQVGPTRELPESGIQLGTPREKVP---AGRSKAELRAE 103 +++ +E+ G AV A+ +V L E G + P +K P + Sbjct: 101 QERLQEDTSFGGNLGRAVFQAKKRVLEPLGLVEEGAKTA-PGKKRPLESPQEPDSSSGIG 159 Query: 104 RRAKQEAERALKQARKGEQGGPPPKASPSTAGETPSGVKRLPEYPQVD 151 ++ KQ A++ L G PP+ S ++A + ++ P VD Sbjct: 160 KKGKQPAKKRLNFEEDTGAGDGPPEGSDTSAMSSDIEMRAAPGGNAVD 207 >3W0L-B nrPDB Length = 619 Score = 32.2 bits (71), Expect = 0.66, Method: Composition-based stats. Identities = 17/88 (19%), Positives = 32/88 (36%) Query: 101 RAERRAKQEAERALKQARKGEQGGPPPKASPSTAGETPSGVKRLPEYPQVDDLLLRRLVK 160 R +++Q L Q+ GEQ + + AG + + P LLR Sbjct: 524 RLTGQSQQRCTEVLLQSIYGEQTLSEQIRNTTIAGHVEAAASQDKVLPVAIVSLLRSCTI 583 Query: 161 KPERQQVPTRKDYGSKVSLFSHLPQYSR 188 + R ++ + S + ++P R Sbjct: 584 QDSRSRINSSLSIRSAIESSMNVPGRKR 611 >3TSB-A nrPDB Length = 511 Score = 31.8 bits (70), Expect = 0.85, Method: Composition-based stats. Identities = 38/202 (18%), Positives = 64/202 (31%), Gaps = 25/202 (12%) Query: 238 QDYTTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAK 297 Q T P LS K + L PL + L IT K E Sbjct: 185 QLITAPVGTTLSEAEKILQKYKIEKL----PLVDNNGV----LQGLITIKDIEKVIEFPN 236 Query: 298 SELRAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILV---YGCSSLVSRILQEAWTEGR 354 S V + + A A++R ++ D I++ +G S V ++E + Sbjct: 237 SAKDKQGRLLVGAAVGVTADAMTRIDALVKASVDAIVLDTAHGHSQGVIDKVKEVRAKYP 296 Query: 355 RFRVVVVDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSV 414 ++ + ++L+ AG + I S + ++A V Sbjct: 297 SLNIIAGNVATA----EATKALIEAGANVVKVGIGPGS----------ICTTRVVAGVGV 342 Query: 415 MSRVGTAQLALVARAHNVPVLV 436 A AR H +PV+ Sbjct: 343 PQLTAVYDCATEARKHGIPVIA 364 >5W4C-A nrPDB Length = 371 Score = 31.4 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 14/84 (16%), Positives = 29/84 (34%), Gaps = 3/84 (3%) Query: 364 RPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQL 423 R +L G T +G+ A + A + V+ G + + +++ G+ Sbjct: 153 RLFLPGEETYW---QSGISACAVCDGAVPIFRQKPLAVIGGGDSAAEEATYLTKYGSHVY 209 Query: 424 ALVARAHNVPVLVCCETYKFCERV 447 LV R + + +V Sbjct: 210 VLVRRDELRASKIMAKRLTSHPKV 233 >6QX9-4A nrPDB Length = 683 Score = 30.6 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 25/99 (25%), Positives = 45/99 (45%), Gaps = 15/99 (15%) Query: 24 PGAVGREMTKEEKLQLRKEKKQQKKKRKEEK---GAEPETGSAVSAAQCQVGPTRELPES 80 P +G +TK+E+ +LR++ +++ +K +EK G P P + Sbjct: 433 PVTLGVYLTKKEQKKLRRQTRREAQKELQEKVRLGLMP-----------PPEPKVRISNL 481 Query: 81 GIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARK 119 LGT + P + +A +RA+ +Q+A ARK Sbjct: 482 MRVLGTEAVQDPT-KVEAHVRAQMAKRQKAHEEANAARK 519 >1TYG-A nrPDB Length = 253 Score = 30.6 bits (67), Expect = 1.9, Method: Composition-based stats. Identities = 17/96 (17%), Positives = 34/96 (35%), Gaps = 12/96 (12%) Query: 325 QKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVVVDSRPWLEGR------HTLRSLVH 378 Q + G ++L Y +V ++ G ++ + P G+ + + Sbjct: 119 QLLEEGFIVLPYTSDDVVLA--RKLEELG--VHAIMPGASPIGSGQGILNPLNLSFIIEQ 174 Query: 379 AGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSV 414 A VP ++ + LGA +L N +V Sbjct: 175 AKVPV--IVDAGIGSPKDAAYAMELGADGVLLNTAV 208 >6MAT-A nrPDB Length = 813 Score = 29.5 bits (64), Expect = 3.8, Method: Composition-based stats. Identities = 34/149 (22%), Positives = 53/149 (35%), Gaps = 14/149 (9%) Query: 26 AVGREMTK-EEKLQLRKEKKQQKKKRKEEKGAEPETGSAVSAAQ--------CQVGPTRE 76 AV +E K EE+ + Q+++R+ +K A+ + + + Q G Sbjct: 69 AVRKEQAKAEEETDSDDLIEAQERERERQKAAQAQRDANLLNRQIAKSWGFASSPGAKAA 128 Query: 77 LPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARKGEQGGPPP-----KASP 131 E G G+ PA + AE A L + Q P KA+P Sbjct: 129 DGEKGTDTGSIATPAPATPAVAENMAADTPTTSTGPVLPASSTDRQPNGEPRPKKRKAAP 188 Query: 132 STAGETPSGVKRLPEYPQVDDLLLRRLVK 160 TP + + VDD L R L + Sbjct: 189 KEIDRTPPTKVSILDIAGVDDTLQRLLKE 217 >4D5Y-M nrPDB Length = 215 Score = 29.1 bits (63), Expect = 4.4, Method: Composition-based stats. Identities = 27/107 (25%), Positives = 44/107 (41%), Gaps = 12/107 (11%) Query: 30 EMTKEEKLQLRKEKKQQKKKRK------EEKGAEPETGSAVSAAQCQVGPTRELPESGIQ 83 ++ K +K++ R K + KK +K K A G+A +AA + Sbjct: 111 KVMKAKKMRNRIIKNEVKKLQKAALLKASPKKAPGTKGTAAAAAAAAAAKVPAKKITAAS 170 Query: 84 LGTPREKVPAGRSKAELRAERRAKQEAERALKQARKGEQGGPPPKAS 130 P +KVPA ++ + A Q+ ++A Q P PKAS Sbjct: 171 KKAPAQKVPAQKATGQKAAPAPKAQKGQKAPAQK------APAPKAS 211 >5L3D-A nrPDB Length = 852 Score = 28.7 bits (62), Expect = 6.6, Method: Composition-based stats. Identities = 21/86 (24%), Positives = 31/86 (36%), Gaps = 10/86 (11%) Query: 14 SGMKAELPPGPGAVGREMTKEEKLQLRKEKKQQKKKRKEEKGAEPETGSAVSAAQCQVGP 73 +G+ GPGAVG R +K++ + G GSA A V P Sbjct: 42 AGLSGPAEVGPGAVGE----------RTPRKKEPPRASPPGGLAEPPGSAGPQAGPTVVP 91 Query: 74 TRELPESGIQLGTPREKVPAGRSKAE 99 P TP + + R +A+ Sbjct: 92 GSATPMETGIAETPEGRRTSRRKRAK 117 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.304 0.115 0.283 Lambda K H 0.267 0.0350 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,118,944 Number of Sequences: 36641 Number of extensions: 579874 Number of successful extensions: 2716 Number of sequences better than 10.0: 68 Number of HSP's better than 10.0 without gapping: 59 Number of HSP's successfully gapped in prelim test: 69 Number of HSP's that attempted gapping in prelim test: 2423 Number of HSP's gapped (non-prelim): 210 length of query: 523 length of database: 10,336,785 effective HSP length: 102 effective length of query: 421 effective length of database: 6,599,403 effective search space: 2778348663 effective search space used: 2778348663 T: 11 A: 40 X1: 16 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 61 (28.3 bits)