BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9UHN1 (485 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5C52-B nrPDB 997 0.0 5C53-B nrPDB 920 0.0 3IKL-A nrPDB 920 0.0 3IKM-B nrPDB 881 0.0 1G5I-A nrPDB 723 0.0 1B76-A nrPDB 113 2e-25 1ATI-A nrPDB 105 6e-23 5Z5E-A nrPDB 57 1e-08 1QE0-A nrPDB 32 0.59 2PME-A nrPDB 32 0.78 1AII-A nrPDB 31 0.93 5BNT-C nrPDB 30 2.6 5UCM-A nrPDB 29 5.9 5HFU-A nrPDB 28 8.9 >5C52-B nrPDB Length = 485 Score = 997 bits (2577), Expect = 0.0, Method: Compositional matrix adjust. Identities = 484/485 (99%), Positives = 484/485 (99%) Query: 1 MRSRVAVRACHKVCRCLLSGFGGRVDAGQPELLTERSSPKGGHVKSHAELEGNGEHPEAP 60 MRSRVAVRACHKVCRCLLSGFGGRVDAGQPELLTERSSPKGGHVKSHAELEGNGEHPEAP Sbjct: 1 MRSRVAVRACHKVCRCLLSGFGGRVDAGQPELLTERSSPKGGHVKSHAELEGNGEHPEAP 60 Query: 61 GSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVV 120 GSGEGS ALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVV Sbjct: 61 GSGEGSLALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVV 120 Query: 121 FREQVFPVDALHHKPGPLLPGDSAFRLVSAETLREILQDKELSKEQLVAFLENVLKTSGK 180 FREQVFPVDALHHKPGPLLPGDSAFRLVSAETLREILQDKELSKEQLVAFLENVLKTSGK Sbjct: 121 FREQVFPVDALHHKPGPLLPGDSAFRLVSAETLREILQDKELSKEQLVAFLENVLKTSGK 180 Query: 181 LRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLV 240 LRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLV Sbjct: 181 LRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLV 240 Query: 241 WFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKELI 300 WFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKELI Sbjct: 241 WFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKELI 300 Query: 301 ETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTENS 360 ETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTENS Sbjct: 301 ETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTENS 360 Query: 361 FTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYLET 420 FTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYLET Sbjct: 361 FTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYLET 420 Query: 421 MQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYIS 480 MQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYIS Sbjct: 421 MQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYIS 480 Query: 481 SAKNV 485 SAKNV Sbjct: 481 SAKNV 485 >5C53-B nrPDB Length = 903 Score = 920 bits (2379), Expect = 0.0, Method: Compositional matrix adjust. Identities = 452/485 (93%), Positives = 452/485 (93%), Gaps = 33/485 (6%) Query: 1 MRSRVAVRACHKVCRCLLSGFGGRVDAGQPELLTERSSPKGGHVKSHAELEGNGEHPEAP 60 MRSRVAVRACHKVCRCLLSGFGGRVDAGQPELLTERSSPKGGHVKSHAELEGNGEHPEAP Sbjct: 1 MRSRVAVRACHKVCRCLLSGFGGRVDAGQPELLTERSSPKGGHVKSHAELEGNGEHPEAP 60 Query: 61 GSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVV 120 GSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVV Sbjct: 61 GSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVV 120 Query: 121 FREQVFPVDALHHKPGPLLPGDSAFRLVSAETLREILQDKELSKEQLVAFLENVLKTSGK 180 FREQVFPVDALHHKPGPLLPGDSAFR K Sbjct: 121 FREQVFPVDALHHKPGPLLPGDSAFR---------------------------------K 147 Query: 181 LRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLV 240 LRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLV Sbjct: 148 LRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLV 207 Query: 241 WFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKELI 300 WFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKELI Sbjct: 208 WFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKELI 267 Query: 301 ETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTENS 360 ETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTENS Sbjct: 268 ETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTENS 327 Query: 361 FTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYLET 420 FTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYLET Sbjct: 328 FTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYLET 387 Query: 421 MQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYIS 480 MQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYIS Sbjct: 388 MQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYIS 447 Query: 481 SAKNV 485 SAKNV Sbjct: 448 SAKNV 452 Score = 919 bits (2374), Expect = 0.0, Method: Compositional matrix adjust. Identities = 451/485 (92%), Positives = 451/485 (92%), Gaps = 34/485 (7%) Query: 1 MRSRVAVRACHKVCRCLLSGFGGRVDAGQPELLTERSSPKGGHVKSHAELEGNGEHPEAP 60 MRSRVAVRACHKVCRCLLSGFGGRVDAGQPELLTERSSPKGGHVKSHAELEGNGEHPEAP Sbjct: 453 MRSRVAVRACHKVCRCLLSGFGGRVDAGQPELLTERSSPKGGHVKSHAELEGNGEHPEAP 512 Query: 61 GSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVV 120 GSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVV Sbjct: 513 GSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVV 572 Query: 121 FREQVFPVDALHHKPGPLLPGDSAFRLVSAETLREILQDKELSKEQLVAFLENVLKTSGK 180 FREQVFPVDALHHKPGPLLPGDSAFRL Sbjct: 573 FREQVFPVDALHHKPGPLLPGDSAFRL--------------------------------- 599 Query: 181 LRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLV 240 RENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLV Sbjct: 600 -RENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLV 658 Query: 241 WFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKELI 300 WFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKELI Sbjct: 659 WFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKELI 718 Query: 301 ETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTENS 360 ETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTENS Sbjct: 719 ETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTENS 778 Query: 361 FTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYLET 420 FTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYLET Sbjct: 779 FTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYLET 838 Query: 421 MQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYIS 480 MQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYIS Sbjct: 839 MQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYIS 898 Query: 481 SAKNV 485 SAKNV Sbjct: 899 SAKNV 903 >3IKL-A nrPDB Length = 459 Score = 920 bits (2378), Expect = 0.0, Method: Compositional matrix adjust. Identities = 452/485 (93%), Positives = 452/485 (93%), Gaps = 32/485 (6%) Query: 1 MRSRVAVRACHKVCRCLLSGFGGRVDAGQPELLTERSSPKGGHVKSHAELEGNGEHPEAP 60 MRSRVAVRACHKVCRCLLSGFGGRVDAGQPELLTERSSPKGGHVKSHAELEGNGEHPEAP Sbjct: 1 MRSRVAVRACHKVCRCLLSGFGGRVDAGQPELLTERSSPKGGHVKSHAELEGNGEHPEAP 60 Query: 61 GSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVV 120 GSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVV Sbjct: 61 GSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVV 120 Query: 121 FREQVFPVDALHHKPGPLLPGDSAFRLVSAETLREILQDKELSKEQLVAFLENVLKTSGK 180 FREQVFPVDALHHKPGPLLPGDSAFR G Sbjct: 121 FREQVFPVDALHHKPGPLLPGDSAFR--------------------------------GG 148 Query: 181 LRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLV 240 LRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLV Sbjct: 149 LRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLV 208 Query: 241 WFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKELI 300 WFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKELI Sbjct: 209 WFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKELI 268 Query: 301 ETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTENS 360 ETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTENS Sbjct: 269 ETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTENS 328 Query: 361 FTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYLET 420 FTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYLET Sbjct: 329 FTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYLET 388 Query: 421 MQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYIS 480 MQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYIS Sbjct: 389 MQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYIS 448 Query: 481 SAKNV 485 SAKNV Sbjct: 449 SAKNV 453 >3IKM-B nrPDB Length = 427 Score = 881 bits (2277), Expect = 0.0, Method: Compositional matrix adjust. Identities = 427/427 (100%), Positives = 427/427 (100%) Query: 59 APGSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSV 118 APGSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSV Sbjct: 1 APGSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSV 60 Query: 119 VVFREQVFPVDALHHKPGPLLPGDSAFRLVSAETLREILQDKELSKEQLVAFLENVLKTS 178 VVFREQVFPVDALHHKPGPLLPGDSAFRLVSAETLREILQDKELSKEQLVAFLENVLKTS Sbjct: 61 VVFREQVFPVDALHHKPGPLLPGDSAFRLVSAETLREILQDKELSKEQLVAFLENVLKTS 120 Query: 179 GKLRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEAS 238 GKLRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEAS Sbjct: 121 GKLRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEAS 180 Query: 239 LVWFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKE 298 LVWFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKE Sbjct: 181 LVWFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKE 240 Query: 299 LIETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTE 358 LIETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTE Sbjct: 241 LIETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTE 300 Query: 359 NSFTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYL 418 NSFTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYL Sbjct: 301 NSFTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYL 360 Query: 419 ETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKY 478 ETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKY Sbjct: 361 ETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKY 420 Query: 479 ISSAKNV 485 ISSAKNV Sbjct: 421 ISSAKNV 427 >1G5I-A nrPDB Length = 454 Score = 723 bits (1867), Expect = 0.0, Method: Compositional matrix adjust. Identities = 341/431 (79%), Positives = 384/431 (89%) Query: 55 EHPEAPGSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEW 114 + P+AP EAL+++C+RRHFLSG+ QQLS +LLSGCH FGPLGVELRKNLA++W Sbjct: 13 QQPDAPEHAVAREALVDLCRRRHFLSGTPQQLSTAALLSGCHARFGPLGVELRKNLASQW 72 Query: 115 WTSVVVFREQVFPVDALHHKPGPLLPGDSAFRLVSAETLREILQDKELSKEQLVAFLENV 174 W+S+VVFREQVF VD+LH +PG P DSAFRLVS E++REILQD+E SKEQLVAFLEN+ Sbjct: 73 WSSMVVFREQVFAVDSLHQEPGSSQPRDSAFRLVSPESIREILQDREPSKEQLVAFLENL 132 Query: 175 LKTSGKLRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEK 234 LKTSGKLR LLHGALEHYVNCLDLVN++LP+GLAQIGVCFHPV ++ Q + V +GEK Sbjct: 133 LKTSGKLRATLLHGALEHYVNCLDLVNRKLPFGLAQIGVCFHPVSNSNQTPSSVTRVGEK 192 Query: 235 TEASLVWFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFP 294 TEASLVWFTP RTS+QWLDFWLRHRL WWRKFAMSPSNFSS+DCQDE GRKG+KLYY+FP Sbjct: 193 TEASLVWFTPTRTSSQWLDFWLRHRLLWWRKFAMSPSNFSSADCQDELGRKGSKLYYSFP 252 Query: 295 WGKELIETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSF 354 WGKE IETLWNLGD ELLH YPGNVS + GRDGRKNVVPCVLSV+GD+D G LAYLYDSF Sbjct: 253 WGKEPIETLWNLGDQELLHTYPGNVSTIQGRDGRKNVVPCVLSVSGDVDLGTLAYLYDSF 312 Query: 355 QLTENSFTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVW 414 QL ENSF RKK+L RKVLKLHPCLAPIKVALDVG+GPT+ELRQVCQGL NELLENGISVW Sbjct: 313 QLAENSFARKKSLQRKVLKLHPCLAPIKVALDVGKGPTVELRQVCQGLLNELLENGISVW 372 Query: 415 PGYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDF 474 PGY ET+ SSLEQL+SKYDEMS+LF+VLVTETTLENGLI LRSRDTTMKEMMHISKL+DF Sbjct: 373 PGYSETVHSSLEQLHSKYDEMSVLFSVLVTETTLENGLIQLRSRDTTMKEMMHISKLRDF 432 Query: 475 LIKYISSAKNV 485 L+KY++SA NV Sbjct: 433 LVKYLASASNV 443 >1B76-A nrPDB Length = 442 Score = 113 bits (283), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 120/455 (26%), Positives = 189/455 (41%), Gaps = 70/455 (15%) Query: 67 EALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVVFREQVF 126 + L+ +C+RR F+ S + L G + +GPLGVEL+ NL WW V R+ + Sbjct: 6 DELVALCKRRGFIFQSSEIYGG---LQGVY-DYGPLGVELKNNLKQAWWRRNVYERDDME 61 Query: 127 PVDA--------LHHK------PGPLLPGDSAFRLVSAETLREILQDKELSK--EQLVAF 170 +DA LH+ P++ A + QD + L+A+ Sbjct: 62 GLDASVLTHRLVLHYSGHEATFADPMVDNAKARYWTPPRYFNMMFQDLRGPRGGRGLLAY 121 Query: 171 LENVLKTSGKLRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKS 230 L R G ++ N LD +++L +G+AQIG F + RN + Sbjct: 122 L----------RPETAQGIFVNFKNVLDATSRKLGFGIAQIGKAFR---NEITPRNFIFR 168 Query: 231 IGEKTEASLVWFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNK-- 288 + E + + +F P W +W+ RL+WW++ +S N E K Sbjct: 169 VREFEQMEIEYFVRPGEDEYWHRYWVEERLKWWQEMGLSRENLVPYQQPPESSAHYAKAT 228 Query: 289 --LYYNFPWGKELIE-----TLWNLGDHELLHMYPG----------NVSKLHGRDGR--K 329 + Y FP G +E T ++LG H G + +L RD K Sbjct: 229 VDILYRFPHGSLELEGIAQRTDFDLGSHTKDQEALGITARVLRNEHSTQRLAYRDPETGK 288 Query: 330 NVVPCVLSVNGDLDRGMLAYLYDSFQLTENSFTRKKNLHRKVLKLHPCLAPIKVALDVGR 389 VP V+ + +DRG+LA L ++F E R VLKL P LAPIKVA+ Sbjct: 289 WFVPYVIEPSAGVDRGVLALLAEAFTREELP----NGEERIVLKLKPQLAPIKVAVIPLV 344 Query: 390 GPTLELRQVCQGLFNELLENGISVWPGYLETMQSSLEQLYSKYDEMSILFTVLVTETTL- 448 E+ + + L LL G+ L ++ + Y ++DE+ F V V T+ Sbjct: 345 KNRPEITEYAKRLKARLLALGLG---RVLYEDTGNIGKAYRRHDEVGTPFAVTVDYDTIG 401 Query: 449 --ENGLIHL------RSRDTTMKEMMHISKLKDFL 475 ++G L R RDT + +H+ +L+ FL Sbjct: 402 QSKDGTTRLKDTVTVRDRDTMEQIRLHVDELEGFL 436 >1ATI-A nrPDB Length = 505 Score = 105 bits (261), Expect = 6e-23, Method: Compositional matrix adjust. Identities = 124/508 (24%), Positives = 201/508 (39%), Gaps = 113/508 (22%) Query: 67 EALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVVFREQVF 126 + L+ +C+RR F+ S + L G + +GPLGVEL+ NL WW V R+ + Sbjct: 6 DELVALCKRRGFIFQSSEIYGG---LQGVY-DYGPLGVELKNNLKQAWWRRNVYERDDME 61 Query: 127 PVDA--------LHHK------PGPLLPG---------DSAFRLVSAETLREILQDKELS 163 +DA LH+ P++ D + E L+ + + E+ Sbjct: 62 GLDASVLTHRLVLHYSGHEATFADPMVDNRITKKRYRLDHLLKEQPEEVLKRLYRAMEVE 121 Query: 164 KEQLVAFLENVLKT-----------------SGK-------------------------- 180 +E L A ++ +++ SG+ Sbjct: 122 EENLHALVQAMMQAPERAGGAMTAAGVLDPASGEPGDWTPPRYFNMMFQDLRGPRGGRGL 181 Query: 181 ---LRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEA 237 LR G ++ N LD +++L +G+AQIG F + RN + + E + Sbjct: 182 LAYLRPETAQGIFVNFKNVLDATSRKLGFGIAQIGKAFR---NEITPRNFIFRVREFEQM 238 Query: 238 SLVWFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNK----LYYNF 293 + +F P W +W+ RL+WW++ +S N E K + Y F Sbjct: 239 EIEYFVRPGEDEYWHRYWVEERLKWWQEMGLSRENLVPYQQPPESSAHYAKATVDILYRF 298 Query: 294 PWGKELIE-----TLWNLGDHELLHMYPG----------NVSKLHGRDGR--KNVVPCVL 336 P G +E T ++LG H G + +L RD K VP V+ Sbjct: 299 PHGSLELEGIAQRTDFDLGSHTKDQEALGITARVLRNEHSTQRLAYRDPETGKWFVPYVI 358 Query: 337 SVNGDLDRGMLAYLYDSFQLTENSFTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELR 396 + +DRG+LA L ++F E R VLKL P LAPIKVA+ E+ Sbjct: 359 EPSAGVDRGVLALLAEAFTREELP----NGEERIVLKLKPQLAPIKVAVIPLVKNRPEIT 414 Query: 397 QVCQGLFNELLENGISVWPGYLETMQSSLEQLYSKYDEMSILFTVLVTETTL---ENGLI 453 + + L LL G+ L ++ + Y ++DE+ F V V T+ ++G Sbjct: 415 EYAKRLKARLLALGLG---RVLYEDTGNIGKAYRRHDEVGTPFAVTVDYDTIGQSKDGTT 471 Query: 454 HL------RSRDTTMKEMMHISKLKDFL 475 L R RDT + +H+ +L+ FL Sbjct: 472 RLKDTVTVRDRDTMEQIRLHVDELEGFL 499 >5Z5E-A nrPDB Length = 534 Score = 57.4 bits (137), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 90/375 (24%), Positives = 159/375 (42%), Gaps = 69/375 (18%) Query: 149 SAETLREILQDKELSKEQ----LVAFLENVLKTSGKLRENLLHGALEHYVNCLDLVNKRL 204 S E L + KE EQ ++ ++ +++ LR G + L ++L Sbjct: 168 SQEALNLLKNLKENVSEQYIKDIIERVKKMVENEAYLRPETAQGPYVMFKREFILHRQKL 227 Query: 205 PYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLVWFTPPRTSN-----------QWLD 253 P GLA +G F +Q+ + + E T+A L F P + +LD Sbjct: 228 PLGLAVVGKAFRNEISPRQL---LLRLREFTQAELQIFFDPEDNEFDINEVKDVELNFLD 284 Query: 254 --------------------FWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLY--- 290 +++ Q++ + + + ++E NK + Sbjct: 285 KEGNYKRIKVKDLPFPEFYAYFVGKVKQFYERLGIPEERLRFRELSEKEKAFYNKYHVDI 344 Query: 291 -YNFP-WGKELIETLWNLGDHELL-HMYPGNVSKLHGRD-----GRKNVVPCVLSVNGDL 342 NFP +G + + + DH+L HM K+ G+D K +P VL ++ + Sbjct: 345 EINFPTYGWKEVGGIHYRTDHDLSGHM------KVSGKDLTVQKDNKKFIPHVLELSFGV 398 Query: 343 DRGMLAYLYDSFQLTENSF-----TRKKNLHRKVLKLHPCLAPIKVAL-DVGRGPTLELR 396 DR +LA L D F LTE + +K R VLK+ LAPIKVA+ + + P EL Sbjct: 399 DRNVLA-LIDLF-LTEEEYEIERDNQKVKEKRVVLKIPKHLAPIKVAVFPLLKKP--ELI 454 Query: 397 QVCQGLFNELLENGISVWPGYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLR 456 + + ++N +L+N +P + Q S+ + Y + DE+ + + + + TLE+ + +R Sbjct: 455 EKAKEVYN-MLKN--YFYPIIYDE-QGSIGRRYRRVDEIGVPYAITIDYQTLEDNTVTIR 510 Query: 457 SRDTTMKEMMHISKL 471 RDT + + I L Sbjct: 511 DRDTMKQVRVKIEDL 525 >1QE0-A nrPDB Length = 420 Score = 32.0 bits (71), Expect = 0.59, Method: Compositional matrix adjust. Identities = 20/76 (26%), Positives = 35/76 (46%), Gaps = 3/76 (3%) Query: 402 LFNELLENGISVWPGYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTT 461 L N L NGI YL Q ++ + D + FT+++ + LEN I +++ T Sbjct: 348 LLNHLRHNGIKADKDYL---QRKIKGQMKQADRLGAKFTIVIGDQELENNKIDVKNMTTG 404 Query: 462 MKEMMHISKLKDFLIK 477 E + + L ++ K Sbjct: 405 ESETIELDALVEYFKK 420 >2PME-A nrPDB Length = 693 Score = 31.6 bits (70), Expect = 0.78, Method: Compositional matrix adjust. Identities = 30/113 (26%), Positives = 46/113 (40%), Gaps = 10/113 (8%) Query: 33 LTERSSPKGGHVKSHAELEGNGEHPEA------PGSGEGSEALLEICQRRHFLSGSKQQL 86 L E +P+ K+ AEL+ EA P A +E +R F Q Sbjct: 27 LKEDKAPQVDVDKAVAELKARKRVLEAKELALQPKDDIVDRAKMEDTLKRRFFY--DQAF 84 Query: 87 SRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVVFREQVFPVDALHHKPGPLL 139 + +SG + FGP+G L+ N+ W + EQ+ +D P P+L Sbjct: 85 AIYGGVSGLY-DFGPVGCALKNNIIQTWRQHFIQ-EEQILEIDCTMLTPEPVL 135 >1AII-A nrPDB Length = 323 Score = 31.2 bits (69), Expect = 0.93, Method: Compositional matrix adjust. Identities = 23/98 (23%), Positives = 42/98 (42%), Gaps = 6/98 (6%) Query: 217 PVFDTKQIRNGVKSIGEKTEASLVWFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSS 276 VFD KQ++ +K G E +L+ RTS Q D + + + S+ +S Sbjct: 92 AVFDAKQLKKSMKGAG-TNEDALIEILTTRTSRQMKDISQAYYTVYKKSLGDDISSETSG 150 Query: 277 DCQD-----EEGRKGNKLYYNFPWGKELIETLWNLGDH 309 D + +GR+ L + K+ + L+ G++ Sbjct: 151 DFRKALLTLADGRRDESLKVDEHLAKQDAQILYKAGEN 188 >5BNT-C nrPDB Length = 378 Score = 30.0 bits (66), Expect = 2.6, Method: Compositional matrix adjust. Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 9/78 (11%) Query: 354 FQLTENSFTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQG------LFNELL 407 F L E F N+ + ++ +AP+K A + TL++ CQG +F +L Sbjct: 35 FDLIEPVFFTTSNVGGQGPEVGKDIAPLKDAYSIDELKTLDVILTCQGGDYTSEVFPKLR 94 Query: 408 ENGISVWPGYLETMQSSL 425 E G W GY SSL Sbjct: 95 EAG---WQGYWIDAASSL 109 >5UCM-A nrPDB Length = 579 Score = 28.9 bits (63), Expect = 5.9, Method: Compositional matrix adjust. Identities = 21/104 (20%), Positives = 49/104 (47%), Gaps = 1/104 (0%) Query: 377 CLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYLETMQSSLEQLYSKYDEMS 436 LAP ++AL + T ++Q L+ EL G V + ++S ++ + + Sbjct: 476 ALAPFQIALVPLKYETESVKQATDKLYAELTAAGFEVLLDDRDK-KTSPGVKFADMELIG 534 Query: 437 ILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYIS 480 I +++++ L G++ + R + + + I +L F+ + +S Sbjct: 535 IPHRIVISDRGLSEGVLEYKGRRDSESQNLPIGELMSFITEKLS 578 >5HFU-A nrPDB Length = 923 Score = 28.1 bits (61), Expect = 8.9, Method: Compositional matrix adjust. Identities = 17/69 (24%), Positives = 37/69 (53%), Gaps = 1/69 (1%) Query: 141 GDSAFRLVSAETLREILQDKELSKEQLVAFLENVLKTSGKLRENLLHGALEHYVNCLDLV 200 G + FR++ + LQ E+ + Q+ A E++++ SG + + L ++++ L + Sbjct: 92 GGTNFRVLWVKVTDNGLQKVEM-ENQIYAIPEDIMRGSGTQLFDHIAECLANFMDKLQIK 150 Query: 201 NKRLPYGLA 209 +K+LP G Sbjct: 151 DKKLPLGFT 159 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5C52-B nrPDB 856 0.0 3IKL-A nrPDB 803 0.0 5C53-B nrPDB 802 0.0 3IKM-B nrPDB 731 0.0 1G5I-A nrPDB 682 0.0 1B76-A nrPDB 512 e-145 1ATI-A nrPDB 498 e-141 5Z5E-A nrPDB 341 3e-94 Sequences not found previously or not previously below threshold: 2PME-A nrPDB 95 7e-20 1NJ2-A nrPDB 58 9e-09 1NJ8-A nrPDB 57 2e-08 3IAL-A nrPDB 48 1e-05 2ZR2-A nrPDB 45 7e-05 1H4S-A nrPDB 45 8e-05 6NAB-A nrPDB 43 3e-04 1NYR-A nrPDB 42 5e-04 1QF6-A nrPDB 39 0.005 4HWO-A nrPDB 39 0.006 1QE0-A nrPDB 38 0.010 5F9Y-A nrPDB 36 0.043 3QO8-A nrPDB 35 0.048 6H9X-A nrPDB 35 0.061 6OTE-A nrPDB 35 0.065 6BLJ-A nrPDB 35 0.083 5W6M-A nrPDB 34 0.12 4X5O-A nrPDB 34 0.16 2X1E-A nrPDB 32 0.72 1WLE-A nrPDB 32 0.85 5E3I-A nrPDB 31 0.89 2LW7-A nrPDB 30 2.4 2WMN-A nrPDB 29 4.9 5CYO-A nrPDB 29 5.6 4JVN-A nrPDB 28 7.7 >5C52-B nrPDB Length = 485 Score = 856 bits (2211), Expect = 0.0, Method: Composition-based stats. Identities = 484/485 (99%), Positives = 484/485 (99%) Query: 1 MRSRVAVRACHKVCRCLLSGFGGRVDAGQPELLTERSSPKGGHVKSHAELEGNGEHPEAP 60 MRSRVAVRACHKVCRCLLSGFGGRVDAGQPELLTERSSPKGGHVKSHAELEGNGEHPEAP Sbjct: 1 MRSRVAVRACHKVCRCLLSGFGGRVDAGQPELLTERSSPKGGHVKSHAELEGNGEHPEAP 60 Query: 61 GSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVV 120 GSGEGS ALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVV Sbjct: 61 GSGEGSLALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVV 120 Query: 121 FREQVFPVDALHHKPGPLLPGDSAFRLVSAETLREILQDKELSKEQLVAFLENVLKTSGK 180 FREQVFPVDALHHKPGPLLPGDSAFRLVSAETLREILQDKELSKEQLVAFLENVLKTSGK Sbjct: 121 FREQVFPVDALHHKPGPLLPGDSAFRLVSAETLREILQDKELSKEQLVAFLENVLKTSGK 180 Query: 181 LRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLV 240 LRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLV Sbjct: 181 LRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLV 240 Query: 241 WFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKELI 300 WFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKELI Sbjct: 241 WFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKELI 300 Query: 301 ETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTENS 360 ETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTENS Sbjct: 301 ETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTENS 360 Query: 361 FTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYLET 420 FTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYLET Sbjct: 361 FTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYLET 420 Query: 421 MQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYIS 480 MQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYIS Sbjct: 421 MQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYIS 480 Query: 481 SAKNV 485 SAKNV Sbjct: 481 SAKNV 485 >3IKL-A nrPDB Length = 459 Score = 803 bits (2073), Expect = 0.0, Method: Composition-based stats. Identities = 452/485 (93%), Positives = 452/485 (93%), Gaps = 32/485 (6%) Query: 1 MRSRVAVRACHKVCRCLLSGFGGRVDAGQPELLTERSSPKGGHVKSHAELEGNGEHPEAP 60 MRSRVAVRACHKVCRCLLSGFGGRVDAGQPELLTERSSPKGGHVKSHAELEGNGEHPEAP Sbjct: 1 MRSRVAVRACHKVCRCLLSGFGGRVDAGQPELLTERSSPKGGHVKSHAELEGNGEHPEAP 60 Query: 61 GSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVV 120 GSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVV Sbjct: 61 GSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVV 120 Query: 121 FREQVFPVDALHHKPGPLLPGDSAFRLVSAETLREILQDKELSKEQLVAFLENVLKTSGK 180 FREQVFPVDALHHKPGPLLPGDSAFR G Sbjct: 121 FREQVFPVDALHHKPGPLLPGDSAFR--------------------------------GG 148 Query: 181 LRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLV 240 LRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLV Sbjct: 149 LRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLV 208 Query: 241 WFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKELI 300 WFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKELI Sbjct: 209 WFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKELI 268 Query: 301 ETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTENS 360 ETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTENS Sbjct: 269 ETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTENS 328 Query: 361 FTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYLET 420 FTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYLET Sbjct: 329 FTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYLET 388 Query: 421 MQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYIS 480 MQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYIS Sbjct: 389 MQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYIS 448 Query: 481 SAKNV 485 SAKNV Sbjct: 449 SAKNV 453 >5C53-B nrPDB Length = 903 Score = 802 bits (2072), Expect = 0.0, Method: Composition-based stats. Identities = 452/485 (93%), Positives = 452/485 (93%), Gaps = 33/485 (6%) Query: 1 MRSRVAVRACHKVCRCLLSGFGGRVDAGQPELLTERSSPKGGHVKSHAELEGNGEHPEAP 60 MRSRVAVRACHKVCRCLLSGFGGRVDAGQPELLTERSSPKGGHVKSHAELEGNGEHPEAP Sbjct: 1 MRSRVAVRACHKVCRCLLSGFGGRVDAGQPELLTERSSPKGGHVKSHAELEGNGEHPEAP 60 Query: 61 GSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVV 120 GSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVV Sbjct: 61 GSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVV 120 Query: 121 FREQVFPVDALHHKPGPLLPGDSAFRLVSAETLREILQDKELSKEQLVAFLENVLKTSGK 180 FREQVFPVDALHHKPGPLLPGDSAFR K Sbjct: 121 FREQVFPVDALHHKPGPLLPGDSAFR---------------------------------K 147 Query: 181 LRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLV 240 LRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLV Sbjct: 148 LRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLV 207 Query: 241 WFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKELI 300 WFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKELI Sbjct: 208 WFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKELI 267 Query: 301 ETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTENS 360 ETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTENS Sbjct: 268 ETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTENS 327 Query: 361 FTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYLET 420 FTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYLET Sbjct: 328 FTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYLET 387 Query: 421 MQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYIS 480 MQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYIS Sbjct: 388 MQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYIS 447 Query: 481 SAKNV 485 SAKNV Sbjct: 448 SAKNV 452 Score = 801 bits (2068), Expect = 0.0, Method: Composition-based stats. Identities = 451/485 (92%), Positives = 451/485 (92%), Gaps = 34/485 (7%) Query: 1 MRSRVAVRACHKVCRCLLSGFGGRVDAGQPELLTERSSPKGGHVKSHAELEGNGEHPEAP 60 MRSRVAVRACHKVCRCLLSGFGGRVDAGQPELLTERSSPKGGHVKSHAELEGNGEHPEAP Sbjct: 453 MRSRVAVRACHKVCRCLLSGFGGRVDAGQPELLTERSSPKGGHVKSHAELEGNGEHPEAP 512 Query: 61 GSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVV 120 GSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVV Sbjct: 513 GSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVV 572 Query: 121 FREQVFPVDALHHKPGPLLPGDSAFRLVSAETLREILQDKELSKEQLVAFLENVLKTSGK 180 FREQVFPVDALHHKPGPLLPGDSAFR Sbjct: 573 FREQVFPVDALHHKPGPLLPGDSAFR---------------------------------- 598 Query: 181 LRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLV 240 LRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLV Sbjct: 599 LRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLV 658 Query: 241 WFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKELI 300 WFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKELI Sbjct: 659 WFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKELI 718 Query: 301 ETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTENS 360 ETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTENS Sbjct: 719 ETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTENS 778 Query: 361 FTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYLET 420 FTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYLET Sbjct: 779 FTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYLET 838 Query: 421 MQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYIS 480 MQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYIS Sbjct: 839 MQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYIS 898 Query: 481 SAKNV 485 SAKNV Sbjct: 899 SAKNV 903 >3IKM-B nrPDB Length = 427 Score = 731 bits (1886), Expect = 0.0, Method: Composition-based stats. Identities = 427/427 (100%), Positives = 427/427 (100%) Query: 59 APGSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSV 118 APGSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSV Sbjct: 1 APGSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSV 60 Query: 119 VVFREQVFPVDALHHKPGPLLPGDSAFRLVSAETLREILQDKELSKEQLVAFLENVLKTS 178 VVFREQVFPVDALHHKPGPLLPGDSAFRLVSAETLREILQDKELSKEQLVAFLENVLKTS Sbjct: 61 VVFREQVFPVDALHHKPGPLLPGDSAFRLVSAETLREILQDKELSKEQLVAFLENVLKTS 120 Query: 179 GKLRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEAS 238 GKLRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEAS Sbjct: 121 GKLRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEAS 180 Query: 239 LVWFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKE 298 LVWFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKE Sbjct: 181 LVWFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKE 240 Query: 299 LIETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTE 358 LIETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTE Sbjct: 241 LIETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTE 300 Query: 359 NSFTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYL 418 NSFTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYL Sbjct: 301 NSFTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYL 360 Query: 419 ETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKY 478 ETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKY Sbjct: 361 ETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKY 420 Query: 479 ISSAKNV 485 ISSAKNV Sbjct: 421 ISSAKNV 427 >1G5I-A nrPDB Length = 454 Score = 682 bits (1759), Expect = 0.0, Method: Composition-based stats. Identities = 341/431 (79%), Positives = 384/431 (89%) Query: 55 EHPEAPGSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEW 114 + P+AP EAL+++C+RRHFLSG+ QQLS +LLSGCH FGPLGVELRKNLA++W Sbjct: 13 QQPDAPEHAVAREALVDLCRRRHFLSGTPQQLSTAALLSGCHARFGPLGVELRKNLASQW 72 Query: 115 WTSVVVFREQVFPVDALHHKPGPLLPGDSAFRLVSAETLREILQDKELSKEQLVAFLENV 174 W+S+VVFREQVF VD+LH +PG P DSAFRLVS E++REILQD+E SKEQLVAFLEN+ Sbjct: 73 WSSMVVFREQVFAVDSLHQEPGSSQPRDSAFRLVSPESIREILQDREPSKEQLVAFLENL 132 Query: 175 LKTSGKLRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEK 234 LKTSGKLR LLHGALEHYVNCLDLVN++LP+GLAQIGVCFHPV ++ Q + V +GEK Sbjct: 133 LKTSGKLRATLLHGALEHYVNCLDLVNRKLPFGLAQIGVCFHPVSNSNQTPSSVTRVGEK 192 Query: 235 TEASLVWFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFP 294 TEASLVWFTP RTS+QWLDFWLRHRL WWRKFAMSPSNFSS+DCQDE GRKG+KLYY+FP Sbjct: 193 TEASLVWFTPTRTSSQWLDFWLRHRLLWWRKFAMSPSNFSSADCQDELGRKGSKLYYSFP 252 Query: 295 WGKELIETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSF 354 WGKE IETLWNLGD ELLH YPGNVS + GRDGRKNVVPCVLSV+GD+D G LAYLYDSF Sbjct: 253 WGKEPIETLWNLGDQELLHTYPGNVSTIQGRDGRKNVVPCVLSVSGDVDLGTLAYLYDSF 312 Query: 355 QLTENSFTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVW 414 QL ENSF RKK+L RKVLKLHPCLAPIKVALDVG+GPT+ELRQVCQGL NELLENGISVW Sbjct: 313 QLAENSFARKKSLQRKVLKLHPCLAPIKVALDVGKGPTVELRQVCQGLLNELLENGISVW 372 Query: 415 PGYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDF 474 PGY ET+ SSLEQL+SKYDEMS+LF+VLVTETTLENGLI LRSRDTTMKEMMHISKL+DF Sbjct: 373 PGYSETVHSSLEQLHSKYDEMSVLFSVLVTETTLENGLIQLRSRDTTMKEMMHISKLRDF 432 Query: 475 LIKYISSAKNV 485 L+KY++SA NV Sbjct: 433 LVKYLASASNV 443 >1B76-A nrPDB Length = 442 Score = 512 bits (1318), Expect = e-145, Method: Composition-based stats. Identities = 120/455 (26%), Positives = 188/455 (41%), Gaps = 70/455 (15%) Query: 67 EALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVVFREQVF 126 + L+ +C+RR F+ S + L G + +GPLGVEL+ NL WW V R+ + Sbjct: 6 DELVALCKRRGFIFQSSEIYGG---LQGVY-DYGPLGVELKNNLKQAWWRRNVYERDDME 61 Query: 127 PVDA--------LHHK------PGPLLPGDSAFRLVSAETLREILQDKELSK--EQLVAF 170 +DA LH+ P++ A + QD + L+A Sbjct: 62 GLDASVLTHRLVLHYSGHEATFADPMVDNAKARYWTPPRYFNMMFQDLRGPRGGRGLLA- 120 Query: 171 LENVLKTSGKLRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKS 230 LR G ++ N LD +++L +G+AQIG F + RN + Sbjct: 121 ---------YLRPETAQGIFVNFKNVLDATSRKLGFGIAQIGKAFR---NEITPRNFIFR 168 Query: 231 IGEKTEASLVWFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNK-- 288 + E + + +F P W +W+ RL+WW++ +S N E K Sbjct: 169 VREFEQMEIEYFVRPGEDEYWHRYWVEERLKWWQEMGLSRENLVPYQQPPESSAHYAKAT 228 Query: 289 --LYYNFPWGKELIE-----TLWNLGDHELLHMYPG----------NVSKLHGRDGR--K 329 + Y FP G +E T ++LG H G + +L RD K Sbjct: 229 VDILYRFPHGSLELEGIAQRTDFDLGSHTKDQEALGITARVLRNEHSTQRLAYRDPETGK 288 Query: 330 NVVPCVLSVNGDLDRGMLAYLYDSFQLTENSFTRKKNLHRKVLKLHPCLAPIKVALDVGR 389 VP V+ + +DRG+LA L ++F E R VLKL P LAPIKVA+ Sbjct: 289 WFVPYVIEPSAGVDRGVLALLAEAFTREELP----NGEERIVLKLKPQLAPIKVAVIPLV 344 Query: 390 GPTLELRQVCQGLFNELLENGISVWPGYLETMQSSLEQLYSKYDEMSILFTVLVTETTL- 448 E+ + + L LL G+ L ++ + Y ++DE+ F V V T+ Sbjct: 345 KNRPEITEYAKRLKARLLALGLG---RVLYEDTGNIGKAYRRHDEVGTPFAVTVDYDTIG 401 Query: 449 --ENGLIHL------RSRDTTMKEMMHISKLKDFL 475 ++G L R RDT + +H+ +L+ FL Sbjct: 402 QSKDGTTRLKDTVTVRDRDTMEQIRLHVDELEGFL 436 >1ATI-A nrPDB Length = 505 Score = 498 bits (1281), Expect = e-141, Method: Composition-based stats. Identities = 122/508 (24%), Positives = 198/508 (38%), Gaps = 113/508 (22%) Query: 67 EALLEICQRRHFLSGSKQQLSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVVFREQVF 126 + L+ +C+RR F+ S + L G + +GPLGVEL+ NL WW V R+ + Sbjct: 6 DELVALCKRRGFIFQSSEIYGG---LQGVY-DYGPLGVELKNNLKQAWWRRNVYERDDME 61 Query: 127 PVDA--------LHHK------PGPLLPG---------DSAFRLVSAETLREILQDKELS 163 +DA LH+ P++ D + E L+ + + E+ Sbjct: 62 GLDASVLTHRLVLHYSGHEATFADPMVDNRITKKRYRLDHLLKEQPEEVLKRLYRAMEVE 121 Query: 164 KEQLVAFLENVLKTS--------------------------------------------- 178 +E L A ++ +++ Sbjct: 122 EENLHALVQAMMQAPERAGGAMTAAGVLDPASGEPGDWTPPRYFNMMFQDLRGPRGGRGL 181 Query: 179 -GKLRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEA 237 LR G ++ N LD +++L +G+AQIG F + RN + + E + Sbjct: 182 LAYLRPETAQGIFVNFKNVLDATSRKLGFGIAQIGKAFR---NEITPRNFIFRVREFEQM 238 Query: 238 SLVWFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNK----LYYNF 293 + +F P W +W+ RL+WW++ +S N E K + Y F Sbjct: 239 EIEYFVRPGEDEYWHRYWVEERLKWWQEMGLSRENLVPYQQPPESSAHYAKATVDILYRF 298 Query: 294 PWGKELIE-----TLWNLGDHELLHMYPG----------NVSKLHGRDGR--KNVVPCVL 336 P G +E T ++LG H G + +L RD K VP V+ Sbjct: 299 PHGSLELEGIAQRTDFDLGSHTKDQEALGITARVLRNEHSTQRLAYRDPETGKWFVPYVI 358 Query: 337 SVNGDLDRGMLAYLYDSFQLTENSFTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELR 396 + +DRG+LA L ++F E R VLKL P LAPIKVA+ E+ Sbjct: 359 EPSAGVDRGVLALLAEAFTREELP----NGEERIVLKLKPQLAPIKVAVIPLVKNRPEIT 414 Query: 397 QVCQGLFNELLENGISVWPGYLETMQSSLEQLYSKYDEMSILFTVLVTETTL---ENGLI 453 + + L LL G+ L ++ + Y ++DE+ F V V T+ ++G Sbjct: 415 EYAKRLKARLLALGLG---RVLYEDTGNIGKAYRRHDEVGTPFAVTVDYDTIGQSKDGTT 471 Query: 454 HL------RSRDTTMKEMMHISKLKDFL 475 L R RDT + +H+ +L+ FL Sbjct: 472 RLKDTVTVRDRDTMEQIRLHVDELEGFL 499 >5Z5E-A nrPDB Length = 534 Score = 341 bits (875), Expect = 3e-94, Method: Composition-based stats. Identities = 86/372 (23%), Positives = 154/372 (41%), Gaps = 55/372 (14%) Query: 149 SAETLREILQDKELSKEQ----LVAFLENVLKTSGKLRENLLHGALEHYVNCLDLVNKRL 204 S E L + KE EQ ++ ++ +++ LR G + L ++L Sbjct: 168 SQEALNLLKNLKENVSEQYIKDIIERVKKMVENEAYLRPETAQGPYVMFKREFILHRQKL 227 Query: 205 PYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLVWFTPPRTSN-----------QWLD 253 P GLA +G F +Q+ + + E T+A L F P + +LD Sbjct: 228 PLGLAVVGKAFRNEISPRQL---LLRLREFTQAELQIFFDPEDNEFDINEVKDVELNFLD 284 Query: 254 --------------------FWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLY--- 290 +++ Q++ + + + ++E NK + Sbjct: 285 KEGNYKRIKVKDLPFPEFYAYFVGKVKQFYERLGIPEERLRFRELSEKEKAFYNKYHVDI 344 Query: 291 -YNFP-WGKELIETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLA 348 NFP +G + + + DH+L + L + K +P VL ++ +DR +LA Sbjct: 345 EINFPTYGWKEVGGIHYRTDHDLSGHMKVSGKDLTVQKDNKKFIPHVLELSFGVDRNVLA 404 Query: 349 YLYDSFQLTENSF-----TRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLF 403 L D F LTE + +K R VLK+ LAPIKVA+ EL + + ++ Sbjct: 405 -LIDLF-LTEEEYEIERDNQKVKEKRVVLKIPKHLAPIKVAVFPLLK-KPELIEKAKEVY 461 Query: 404 NELLENGISVWPGYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMK 463 N +L+N +P + Q S+ + Y + DE+ + + + + TLE+ + +R RDT + Sbjct: 462 N-MLKN--YFYPIIYDE-QGSIGRRYRRVDEIGVPYAITIDYQTLEDNTVTIRDRDTMKQ 517 Query: 464 EMMHISKLKDFL 475 + I L + L Sbjct: 518 VRVKIEDLPNQL 529 >2PME-A nrPDB Length = 693 Score = 94.8 bits (234), Expect = 7e-20, Method: Composition-based stats. Identities = 59/398 (14%), Positives = 109/398 (27%), Gaps = 126/398 (31%) Query: 33 LTERSSPKGGHVKSHAELEGNGEHPEAPGSG-------EGSEALLEICQRRHFLSGSKQQ 85 L E +P+ K+ AEL+ EA + + +RR F + Sbjct: 27 LKEDKAPQVDVDKAVAELKARKRVLEAKELALQPKDDIVDRAKMEDTLKRRFFYDQAFAI 86 Query: 86 LSRDSLLSGCHPGFGPLGVELRKNLAAEWWTSVVVFREQVFPVDALHHKPGPL------- 138 +SG + FGP+G L+ N+ W + EQ+ +D P P+ Sbjct: 87 YGG---VSGLY-DFGPVGCALKNNIIQT-WRQHFIQEEQILEIDCTMLTPEPVLKTSGHV 141 Query: 139 ----------LPGDSAFRL--VSAETLREILQDKELSKEQLVAFLENVLKTSGKLRENLL 186 + FR + L++++ DK+ S E+ + + ++ L Sbjct: 142 DKFADFMVKDVKNGECFRADHLLKAHLQKLMSDKKCSVEKKSEMESVLAQLDNYGQQELA 201 Query: 187 ----------------------------------------------HGALEHYVNCLDLV 200 G ++ L+ Sbjct: 202 DLFVNYNVKSPITGNDLSPPVSFNLMFKTFIGPGGNMPGYLRPETAQGIFLNFKRLLEFN 261 Query: 201 NKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLVWFTPPRT------------- 247 +LP+ AQIG F + R+G+ + E T A + F P Sbjct: 262 QGKLPFAAAQIGNSFR---NEISPRSGLIRVREFTMAEIEHFVDPSEKDHPKFQNVADLH 318 Query: 248 -----------------------------SNQWLDFWLRHRLQWWRKFAMSPSNFSSSDC 278 +N L +++ + K +SP Sbjct: 319 LYLYSAKAQVSGQSARKMRLGDAVEQGVINNTVLGYFIGRIYLYLTKVGISPDKLRFRQH 378 Query: 279 QDEEGRKGN----KLYYNFPWGKELIETLWNLGDHELL 312 + E +G I + ++L Sbjct: 379 MENEMAHYACDCWDAESKTSYGWIEIVGCADRSCYDLS 416 Score = 88.6 bits (218), Expect = 6e-18, Method: Composition-based stats. Identities = 32/145 (22%), Positives = 58/145 (40%), Gaps = 12/145 (8%) Query: 329 KNVVPCVLSVNGDLDRGMLAYLYDSFQLTENSFTRKKNLHRKVLKLHPCLAPIKVALDVG 388 + VVP V+ + L R M +F + R+ + R +AP K ++ Sbjct: 514 EEVVPNVIEPSFGLGRIMYTVFEHTFHV------REGDEQRTFFSFPAVVAPFKCSVLPL 567 Query: 389 RGPTLELRQVCQGLFNELLENGISVWPGYLETMQSSLEQLYSKYDEMSILFTVLVTETTL 448 E + L L +G+S ++ S+ + Y++ DE+ + F V + T+ Sbjct: 568 SQNQ-EFMPFVKELSEALTRHGVSHK---VDDSSGSIGRRYARTDEIGVAFGVTIDFDTV 623 Query: 449 ENG--LIHLRSRDTTMKEMMHISKL 471 LR RD+ + IS+L Sbjct: 624 NKTPHTATLRDRDSMRQIRAEISEL 648 >1NJ2-A nrPDB Length = 501 Score = 57.8 bits (138), Expect = 9e-09, Method: Composition-based stats. Identities = 70/444 (15%), Positives = 140/444 (31%), Gaps = 58/444 (13%) Query: 39 PKGGHVKSHAELEGNGEHPEAPGSGEGSEALLEICQRRHFLSGSKQQLSRDSLLSGCHPG 98 P+G H++ + + N H E + E + H + + + + + G H Sbjct: 16 PRGSHMQKPIKKDPNRYH---------GEKMTEFSEWFHNILEEAEIIDQRYPVKGMHV- 65 Query: 99 FGPLGVELRKNLAAEWWTSVVVFREQVFPVDALHHKPGPLLPGDSAFRLVSAETLREILQ 158 + P G +RKN ++ R+ + L L+P D + A ++ Sbjct: 66 WMPHGFMIRKNTLKIL--RRILDRDHEEVLFPL------LVPEDELAKE--AIHVKGFED 115 Query: 159 DKELSKEQLVAFLENVLKTSGKLRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPV 218 + ++ L+ L LR + + LP Q+ F Sbjct: 116 EVYWVTHGGLSKLQRKLA----LRPTSETVMYPMFALWVRSHTD-LPMRFYQVVNTFRYE 170 Query: 219 FDTKQIRNGVKSIGEKTEASLVWFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDC 278 + V+ I EA + T Q + +++ + + + Sbjct: 171 TKHTRPLIRVREITTFKEAHTIHATASEAEEQVERA-VEIYKEFFNSLGIP---YLITRR 226 Query: 279 QDEEGRKGNKLYYNF----PWGK-ELIETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVP 333 + G++ F P GK I T+ NLG ++ + Sbjct: 227 PPWDKFPGSEYTVAFDTLMPDGKTLQIGTVHNLG------QTFARTFEIKFETPEGDH-E 279 Query: 334 CVLSVNGDLDRGMLAYLYDSFQLTENSFTRKKNLHRKVLKLHPCLAPIKVALDVG--RGP 391 V L ++A + L L P +A +V + + Sbjct: 280 YVHQTCYGLSDRVIASVIAIHGDESG------------LCLPPDVAAHQVVIVPIIFKKA 327 Query: 392 TLELRQVCQGLFNELLENGISVWPGYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENG 451 E+ + C+ L + L G V +L+ + Y +++ + V + LE G Sbjct: 328 AEEVMEACRELRSRLEAAGFRV---HLDDRDIRAGRKYYEWEMRGVPLRVEIGPRDLEKG 384 Query: 452 LIHLRSRDTTMKEMMHISKLKDFL 475 + RDT K + +++ L Sbjct: 385 AAVISRRDTGEKVTADLQGIEETL 408 >1NJ8-A nrPDB Length = 459 Score = 56.7 bits (135), Expect = 2e-08, Method: Composition-based stats. Identities = 45/317 (14%), Positives = 101/317 (31%), Gaps = 35/317 (11%) Query: 172 ENVLKTSGKLRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSI 231 + L LR + + LP + QI F + ++ I Sbjct: 93 KTQLDVKLALRPTSETPIYYMMKLWVKVHTD-LPIKIYQIVNTFRYETKHTRPLIRLREI 151 Query: 232 GEKTEASLVWFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYY 291 EA T + + + +++ + + S + + G + Sbjct: 152 MTFKEAHTAHSTK-EEAENQVKEAISIYKKFFDTLGIP---YLISKRPEWDKFPGAEYTM 207 Query: 292 NF----PWGK-ELIETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGM 346 F P G+ I T+ NLG + G + + Sbjct: 208 AFDTIFPDGRTMQIATVHNLG-QNFSKTFEIIFETPTGDKD------YAYQTCYGISDRV 260 Query: 347 LAYLYDSFQLTENSFTRKKNLHRKVLKLHPCLAPIKVALDVG--RGPTLELRQVCQGLFN 404 +A + + K L L P +API+V + +G + + + ++ Sbjct: 261 IASII------------AIHGDEKGLILPPIVAPIQVVIVPLIFKGKEDIVMEKAKEIYE 308 Query: 405 ELLENGISVWPGYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKE 464 +L + +++ + ++ ++ + + V +EN I L RDT K Sbjct: 309 KL----KGKFRVHIDDRDIRPGRKFNDWEIKGVPLRIEVGPKDIENKKITLFRRDTMEKF 364 Query: 465 MMHISKLKDFLIKYISS 481 + ++L + + K +++ Sbjct: 365 QVDETQLMEVVEKTLNN 381 >3IAL-A nrPDB Length = 518 Score = 47.8 bits (112), Expect = 1e-05, Method: Composition-based stats. Identities = 55/328 (16%), Positives = 102/328 (31%), Gaps = 47/328 (14%) Query: 175 LKTSGKLRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGE- 233 L+ LR + + K LP + Q F + + + E Sbjct: 113 LEERLALRPTSETAIYSMFSKWVRSY-KDLPLKIHQTCTIFRHETKNTKP---LIRVREI 168 Query: 234 -KTEASLVWFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDE-EGRKGNKLY- 290 EA T +Q D+W + + C D G +++ Sbjct: 169 HWNEAHCCHATAEDAVSQLSDYWKVIDTIFSDELCFKGQKLR-RVCWDRFPGADYSEVSD 227 Query: 291 YNFPWGK-ELIETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAY 349 P G+ + NLG + L+ ++V P + + +LA Sbjct: 228 VVMPCGRVLQTAGIHNLG-----QRFSSTFDILYANKANESVHPYL--TCAGISTRVLAC 280 Query: 350 LYDSFQLTENSFTRKKNLHRKVLKLHPCLAPIKVALDV---GRGPTLELRQVCQGLFNEL 406 + + +S L L P +API V + G+ E Q G NE+ Sbjct: 281 ---ALSIHGDSGG---------LVLPPLIAPIHVVIIPIGCGKKNNQESDQQVLGKVNEI 328 Query: 407 ---LENGISVWPGYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDT--- 460 L++ + + + S+ Y+ + + V + L NG + RD Sbjct: 329 ADTLKSKLGLRVSIDDDFSKSMGDKLYYYELKGVPLRIEVGQRDLANGQCIVVPRDVGKD 388 Query: 461 ---------TMKEMMHISKLKDFLIKYI 479 MK H ++ + ++K + Sbjct: 389 QKRVIPITEVMKVSSHTTENHELVVKNV 416 >2ZR2-A nrPDB Length = 455 Score = 45.1 bits (105), Expect = 7e-05, Method: Composition-based stats. Identities = 19/123 (15%), Positives = 44/123 (35%), Gaps = 2/123 (1%) Query: 148 VSAETLREILQDKELSKEQLVAFLENVLKTSGKLRENLLHGALEHYVNCLDLVNKRLPYG 207 + +R +++ S E + V L H + N + L K LP Sbjct: 216 IPPYMVRRFVEEGSTSFEDFEDVIYKVEDEDLYLIPTAEHPLAGMHANEI-LDGKDLPLL 274 Query: 208 LAQIGVCFHPVFDTK-QIRNGVKSIGEKTEASLVWFTPPRTSNQWLDFWLRHRLQWWRKF 266 + CF T + G+ + + + ++ P S +W + +R+ + +++ Sbjct: 275 YVGVSPCFRKEAGTAGKDTKGIFRVHQFHKVEQFVYSRPEESWEWHEKIIRNAEELFQEL 334 Query: 267 AMS 269 + Sbjct: 335 EIP 337 >1H4S-A nrPDB Length = 477 Score = 44.7 bits (104), Expect = 8e-05, Method: Composition-based stats. Identities = 24/89 (26%), Positives = 37/89 (41%), Gaps = 4/89 (4%) Query: 372 LKLHPCLAPIKVALDVGRG--PTLELRQVCQGLFNELLENGISVWPGYLETMQSSLEQLY 429 L L P LAPI+V + + + QGL LL G+ V + Q + + Sbjct: 279 LVLPPRLAPIQVVIVPIYKDESRERVLEAAQGLRQALLAQGLRVH--LDDRDQHTPGYKF 336 Query: 430 SKYDEMSILFTVLVTETTLENGLIHLRSR 458 +++ + F V + LE G L SR Sbjct: 337 HEWELKGVPFRVELGPKDLEGGQAVLASR 365 >6NAB-A nrPDB Length = 513 Score = 43.2 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 25/109 (22%), Positives = 45/109 (41%), Gaps = 5/109 (4%) Query: 374 LHPCLAPIKVALDVGR---GPTLELRQVCQGLFNELLENGISVWPGYLETMQSSLEQLYS 430 L P +A +V + L + + ++NEL + GI V + ++ + Y+ Sbjct: 291 LPPRVAFCQVVVIPLIFKDKDNATLVEKTKEIYNELEKAGIRV--KLDDRLERTPGWKYN 348 Query: 431 KYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYI 479 ++ + + V LE I L RDT K M +S+ IK + Sbjct: 349 YWELRGVPLRIEVGPKDLEKQQIMLCRRDTGEKWTMPLSEFSGDSIKAV 397 >1NYR-A nrPDB Length = 645 Score = 42.4 bits (98), Expect = 5e-04, Method: Composition-based stats. Identities = 44/292 (15%), Positives = 93/292 (31%), Gaps = 33/292 (11%) Query: 202 KRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLVWFTPPRTSNQWLDFWLRHRLQ 261 + LP +A++G +G++ + T F P + + + Sbjct: 351 RELPIRIAELGTMHRYEASGAV--SGLQRVRGMTLNDSHIFVRPDQIKEEFKRVVNMIID 408 Query: 262 WWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKELIETLWNLGDHELLHMYPGNVSK 321 ++ F +F S E+ K ++ E + EL Y + + Sbjct: 409 VYKDFGFEDYSFRLSYRDPEDKEKY----FDDDDMWNKAENMLKEAADELGLSYEEAIGE 464 Query: 322 LHGRDGRKNV-VPCVLSVNGDLDRGMLAYLY-DSFQLT----ENSFTRKKNLHRKVLK-- 373 + +V V + L L +L + F LT + R +HR V+ Sbjct: 465 AAFYGPKLDVQVKTAMGKEETLSTAQLDFLLPERFDLTYIGQDGEHHRPVVIHRGVVSTM 524 Query: 374 --------------LHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYLE 419 LAP +V + + L +EL G+ V ++ Sbjct: 525 ERFVAFLTEETKGAFPTWLAPKQVQIIPV--NVDLHYDYARQLQDELKSQGVRVS---ID 579 Query: 420 TMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKL 471 + + I + ++V + +EN +++R + +E + + Sbjct: 580 DRNEKMGYKIREAQMQKIPYQIVVGDKEVENNQVNVRQYGSQDQETVEKDEF 631 >1QF6-A nrPDB Length = 642 Score = 38.9 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 44/314 (14%), Positives = 94/314 (29%), Gaps = 58/314 (18%) Query: 202 KRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLVWFTPPRTSNQWLDFWLRHRLQ 261 + LP +A+ G C +G+ + T+ F ++ +R Sbjct: 349 RDLPLRMAEFGSCHRNE--PSGSLHGLMRVRGFTQDDAHIFCTEEQIRDEVNGCIRLVYD 406 Query: 262 WWRKFAMS-------------------------------PSNFSSSDCQDEEGRKGN-KL 289 + F N + Q EG K+ Sbjct: 407 MYSTFGFEKIVVKLSTRPEKRIGSDEMWDRAEADLAVALEENNIPFEYQLGEGAFYGPKI 466 Query: 290 YYNFPWGKELIETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAY 349 + + ++ W G +L P +S + + + VP ++ R +L Sbjct: 467 EFTL---YDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNERKVPVMIH------RAILGS 517 Query: 350 LYDSFQLTENSFTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLEN 409 + + F LAP++V V T + L +L Sbjct: 518 MERFIGILTEEFAGF---------FPTWLAPVQV---VIMNITDSQSEYVNELTQKLSNA 565 Query: 410 GISVWPGYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHIS 469 GI V + ++ + + ++ + +E+G + +R+R M ++ Sbjct: 566 GIRVKADLRNE---KIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRRGKDLGSMDVN 622 Query: 470 KLKDFLIKYISSAK 483 ++ + L + I S Sbjct: 623 EVIEKLQQEIRSRS 636 >4HWO-A nrPDB Length = 411 Score = 38.6 bits (88), Expect = 0.006, Method: Composition-based stats. Identities = 44/314 (14%), Positives = 94/314 (29%), Gaps = 58/314 (18%) Query: 202 KRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLVWFTPPRTSNQWLDFWLRHRLQ 261 + LP +A+ G C +G+ + T+ F ++ +R Sbjct: 110 RDLPLRMAEFGSCHRNE--PSGSLHGLMRVRGFTQDDAHIFCTEEQIRDEVNGCIRLVYD 167 Query: 262 WWRKFAMS-------------------------------PSNFSSSDCQDEEGRKGN-KL 289 + F N + Q EG K+ Sbjct: 168 MYSTFGFEKIVVKLSTRPEKRIGSDEMWDRAEADLAVALEENNIPFEYQLGEGAFYGPKI 227 Query: 290 YYNFPWGKELIETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAY 349 + + ++ W G +L P +S + + + VP ++ R +L Sbjct: 228 EFTL---YDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNERKVPVMIH------RAILGS 278 Query: 350 LYDSFQLTENSFTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLEN 409 + + F LAP++V V T + L +L Sbjct: 279 MERFIGILTEEFAGF---------FPTWLAPVQV---VIMNITDSQSEYVNELTQKLSNA 326 Query: 410 GISVWPGYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHIS 469 GI V + ++ + + ++ + +E+G + +R+R M ++ Sbjct: 327 GIRVKADLRNE---KIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRRGKDLGSMDVN 383 Query: 470 KLKDFLIKYISSAK 483 ++ + L + I S Sbjct: 384 EVIEKLQQEIRSRS 397 >1QE0-A nrPDB Length = 420 Score = 37.8 bits (86), Expect = 0.010, Method: Composition-based stats. Identities = 20/81 (24%), Positives = 36/81 (44%), Gaps = 3/81 (3%) Query: 397 QVCQGLFNELLENGISVWPGYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLR 456 + L N L NGI YL Q ++ + D + FT+++ + LEN I ++ Sbjct: 343 RYAVKLLNHLRHNGIKADKDYL---QRKIKGQMKQADRLGAKFTIVIGDQELENNKIDVK 399 Query: 457 SRDTTMKEMMHISKLKDFLIK 477 + T E + + L ++ K Sbjct: 400 NMTTGESETIELDALVEYFKK 420 >5F9Y-A nrPDB Length = 511 Score = 35.9 bits (81), Expect = 0.043, Method: Composition-based stats. Identities = 23/116 (19%), Positives = 49/116 (42%), Gaps = 5/116 (4%) Query: 372 LKLHPCLAPIKVALDVGRGPTL---ELRQVCQGLFNELLENGISVWPGYLETMQSSLEQL 428 L L P +AP++V + T+ E +++C + L + G+ V + + Sbjct: 293 LVLPPKVAPVQVIIIPIIFKTVITEEQKKICNEVECILKKAGVRV--KIDDRSNYTPGWK 350 Query: 429 YSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYISSAKN 484 Y+ ++ + V +E + + RD K + IS+L+ + K + +N Sbjct: 351 YNHWEVKGVCLRFEVGPRDIEKRSVRVVVRDNMEKMDIPISELESKIPKLLEEFQN 406 >3QO8-A nrPDB Length = 485 Score = 35.5 bits (80), Expect = 0.048, Method: Composition-based stats. Identities = 29/219 (13%), Positives = 74/219 (33%), Gaps = 9/219 (4%) Query: 147 LVSAETLREILQDKELSKEQLVAFLENVL--KTSGKLRENLLHGALEHYVNC-LDLVNKR 203 L + + + + K Q L V+ + L ++ + ++ Sbjct: 207 LQAPVMMNKEVMAKTAQLSQFDEELYKVIDGEDEKYLIATSEQPISAYHAGEWFESPAEQ 266 Query: 204 LPYGLAQIGVCFHPVFDTK-QIRNGVKSIGEKTEASLVWFTPPRTSNQWLDFWLRHRLQW 262 LP A CF + + G+ + + T P S + D + ++ Sbjct: 267 LPVRYAGYSSCFRREAGSHGKDAWGIFRVHAFEKIEQFVLTEPEKSWEEFDRMIGCSEEF 326 Query: 263 WRKFAMSPS--NFSSSDCQDEEGRKGN-KLYYNFPWGKELIETLWNLGDHELLHMYPGNV 319 ++ + S + + +K + + ++ F + + + N D++ ++ Sbjct: 327 YQSLGLPYRVVGIVSGELNNAAAKKYDLEAWFPFQQEYKELVSCSNCTDYQSRNLEIRCG 386 Query: 320 SKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTE 358 K + K V C+ S +R + L +++Q + Sbjct: 387 IKQQNQQ-EKKYVHCLNSTLSATERTICCIL-ENYQKED 423 >6H9X-A nrPDB Length = 430 Score = 35.5 bits (80), Expect = 0.061, Method: Composition-based stats. Identities = 21/127 (16%), Positives = 41/127 (32%), Gaps = 4/127 (3%) Query: 146 RLVSAETLREILQDKELSKEQLVAF-LENVLKTSGKLRENLLHGALEHYVNCLDLVNKRL 204 LV+ +TL Q + + + LE +S L + V + L Sbjct: 197 YLVNQDTLYGTGQLPKFAGDLFHTRPLEEEADSSNYALIPTAEVPLTNLVRDEIIDEDDL 256 Query: 205 PYGLAQIGVCFHPVFDT--KQIRNGVKSIGEKTEASLVWFTPPRTSNQWLDFWLRHRLQW 262 P + CF + + R G+ + + + +V P S L+ H + Sbjct: 257 PIKMTAHTPCFRSEAGSYGRDTR-GLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKV 315 Query: 263 WRKFAMS 269 + + Sbjct: 316 LQLLGLP 322 >6OTE-A nrPDB Length = 572 Score = 35.1 bits (79), Expect = 0.065, Method: Composition-based stats. Identities = 19/114 (16%), Positives = 35/114 (30%), Gaps = 4/114 (3%) Query: 177 TSGKLRENLLHGALEHYVNCLDLVNKRLPYGLAQIGVCFHPVFDTKQIRN-GVKSIGEKT 235 S L + N L +K LP A I CF G+ I + Sbjct: 361 NSLFLIATSEQPIAAMHHNV-TLEDKDLPIKYAGISTCFRKEAGAHGKDTWGIFRIHQFE 419 Query: 236 EASLVWFTPPRTSNQWLDFWLRHRLQWWRKFAMSPS--NFSSSDCQDEEGRKGN 287 + T P S + + + ++++ + + S D +K + Sbjct: 420 KVEQFCVTLPEDSQKIHEEMISISEEFYQSLELPYRVISIVSGALNDAASKKYD 473 >6BLJ-A nrPDB Length = 485 Score = 34.7 bits (78), Expect = 0.083, Method: Composition-based stats. Identities = 17/111 (15%), Positives = 36/111 (32%), Gaps = 7/111 (6%) Query: 166 QLVAFLENVLKTSGKLRENLLHGALEHYVNCLDLVNK----RLPYGLAQIGVCFHPVFDT 221 QL F E + +G+ + L E + L + LP + CF Sbjct: 260 QLSQFDEELYTVTGEGEDKYLIATSEQPIAAFHLEKRFDESELPIKYCGMSTCFRKEVGA 319 Query: 222 KQIRN-GVKSIGEKTEASLVWFTPPRTSNQW--LDFWLRHRLQWWRKFAMS 269 G+ + + + T P+ + W D + + +++ + Sbjct: 320 HGKDTLGIFRVHQFEKIEQFVVTSPKDNKSWEMFDEMIGNSEAFYQSLGIP 370 >5W6M-A nrPDB Length = 450 Score = 34.3 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 29/146 (19%), Positives = 52/146 (35%), Gaps = 22/146 (15%) Query: 326 DGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTENSFTRKKNLHRKVLKLHPCLAPIKVAL 385 D + VPCV ++ ++R F + E R + L K+ + Sbjct: 318 DPKGRKVPCV-GLSIGVER--------IFSIVEQ---RLEALEEKIRTTETQV------- 358 Query: 386 DVGRGPTLELRQVCQGLFNELLENGISVWPGYLETMQSSLEQLYSKYDEMSILFTVLVTE 445 + +L + L +EL + GI L L +E I ++ E Sbjct: 359 -LVASAQKKLLEERLKLVSELWDAGIKAE--LLYKKNPKLLNQLQYCEEAGIPLVAIIGE 415 Query: 446 TTLENGLIHLRSRDTTMKEMMHISKL 471 L++G+I LRS + + + L Sbjct: 416 QELKDGVIKLRSVTSREEVDVRREDL 441 >4X5O-A nrPDB Length = 509 Score = 33.9 bits (76), Expect = 0.16, Method: Composition-based stats. Identities = 29/146 (19%), Positives = 52/146 (35%), Gaps = 22/146 (15%) Query: 326 DGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTENSFTRKKNLHRKVLKLHPCLAPIKVAL 385 D + VPCV ++ ++R F + E R + L K+ + Sbjct: 371 DPKGRKVPCV-GLSIGVER--------IFSIVEQ---RLEALEEKIRTTETQV------- 411 Query: 386 DVGRGPTLELRQVCQGLFNELLENGISVWPGYLETMQSSLEQLYSKYDEMSILFTVLVTE 445 + +L + L +EL + GI L L +E I ++ E Sbjct: 412 -LVASAQKKLLEERLKLVSELWDAGIKAE--LLYKKNPKLLNQLQYCEEAGIPLVAIIGE 468 Query: 446 TTLENGLIHLRSRDTTMKEMMHISKL 471 L++G+I LRS + + + L Sbjct: 469 QELKDGVIKLRSVTSREEVDVRREDL 494 >2X1E-A nrPDB Length = 357 Score = 31.6 bits (70), Expect = 0.72, Method: Composition-based stats. Identities = 23/103 (22%), Positives = 40/103 (38%), Gaps = 4/103 (3%) Query: 381 IKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYLETMQSSLEQLYSKYDEMSILFT 440 I A+D+ RG T + + + + ++L WP Y E ++ + E+ Sbjct: 29 IDFAVDLIRGKTKKTDEELKQVLSQLGRVIEERWPKYYEEIRGIAKGAERDVSEI----V 84 Query: 441 VLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYISSAK 483 +L T T GL R TT + L+ + S+ K Sbjct: 85 MLNTRTEFAYGLKAARDGCTTAYCQLPNGALQGQNWDFFSATK 127 >1WLE-A nrPDB Length = 501 Score = 31.6 bits (70), Expect = 0.85, Method: Composition-based stats. Identities = 15/83 (18%), Positives = 34/83 (40%), Gaps = 5/83 (6%) Query: 202 KRLPYGLAQIGVCFHPVFDTKQIRNGVKSIGEKTEASLVWFTPPR--TSNQWLDFWLRHR 259 + LP + C+ DT + G+ + T+ + T P S++ L+ +L + Sbjct: 299 RDLPIRMVCSSTCYRAETDTGKEPWGLYRVHHFTKVEMFGVTGPGLEQSSELLEEFLSLQ 358 Query: 260 LQWWRKFAMSPSNFSSSDCQDEE 282 ++ + + +F D +E Sbjct: 359 MEILTELGL---HFRVLDMPTQE 378 >5E3I-A nrPDB Length = 438 Score = 31.2 bits (69), Expect = 0.89, Method: Composition-based stats. Identities = 11/56 (19%), Positives = 28/56 (50%) Query: 422 QSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIK 477 Q S++ K D+ ++ +++ E E + ++ T + + +++L FLI+ Sbjct: 379 QGSMKSQMKKADQAGAVYAIILGEREWEAQQLAVKELATAEQSQVALAELVPFLIE 434 >2LW7-A nrPDB Length = 170 Score = 30.1 bits (66), Expect = 2.4, Method: Composition-based stats. Identities = 10/39 (25%), Positives = 19/39 (48%) Query: 433 DEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKL 471 +E I ++ E L++G+I LRS + + + L Sbjct: 117 EEAGIPLVAIIGEQELKDGVIKLRSVTSREEVDVRREDL 155 >2WMN-A nrPDB Length = 428 Score = 28.9 bits (63), Expect = 4.9, Method: Composition-based stats. Identities = 12/37 (32%), Positives = 20/37 (54%) Query: 375 HPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGI 411 H L PI+VA+D ELRQ+C ++++ + Sbjct: 301 HTDLNPIEVAIDEMSKKVAELRQLCSSAEVDMIKLQL 337 >5CYO-A nrPDB Length = 274 Score = 28.9 bits (63), Expect = 5.6, Method: Composition-based stats. Identities = 18/67 (26%), Positives = 28/67 (41%), Gaps = 1/67 (1%) Query: 394 ELRQVCQGLFNELLENGISVWPGYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLI 453 E Q + +LL NGI V+P S + K+ EM I F V+ ++ + Sbjct: 159 ERVHFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREM-IPFAVVGSDHEYQVNGK 217 Query: 454 HLRSRDT 460 + R T Sbjct: 218 RILGRKT 224 >4JVN-A nrPDB Length = 294 Score = 28.2 bits (61), Expect = 7.7, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 21/67 (31%) Query: 255 WLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKELIETLWNLGDHELLHM 314 W +H WW K F + E+ RK +F K E + + H Sbjct: 171 WYKHVKSWWEKGKSPRVLFLFYEDLKEDIRKEVIKLIHFLERKPSEELVDRIIHHTSFQE 230 Query: 315 YPGNVSK 321 N S Sbjct: 231 MKNNPST 237 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.129 0.348 Lambda K H 0.267 0.0391 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 18,075,234 Number of Sequences: 36641 Number of extensions: 730764 Number of successful extensions: 1891 Number of sequences better than 10.0: 34 Number of HSP's better than 10.0 without gapping: 28 Number of HSP's successfully gapped in prelim test: 24 Number of HSP's that attempted gapping in prelim test: 1798 Number of HSP's gapped (non-prelim): 75 length of query: 485 length of database: 10,336,785 effective HSP length: 101 effective length of query: 384 effective length of database: 6,636,044 effective search space: 2548240896 effective search space used: 2548240896 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 61 (28.2 bits)