BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9UBQ7 (328 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2WWR-A nrPDB 672 0.0 5AOV-A nrPDB 223 8e-59 6BII-A nrPDB 211 5e-55 2DBZ-A nrPDB 203 1e-52 2CUK-A nrPDB 194 5e-50 4G2N-A nrPDB 181 4e-46 1GDH-A nrPDB 172 2e-43 3BA1-A nrPDB 166 1e-41 2D0I-A nrPDB 149 2e-36 4EBF-A nrPDB 139 2e-33 1WWK-A nrPDB 138 4e-33 5TX7-A nrPDB 136 1e-32 4DGS-A nrPDB 136 1e-32 5UOG-A nrPDB 135 2e-32 2G76-A nrPDB 135 3e-32 3DC2-A nrPDB 135 3e-32 4ZGS-A nrPDB 122 1e-28 6IH4-A nrPDB 122 2e-28 4LSW-A nrPDB 122 2e-28 3WNV-A nrPDB 119 2e-27 5OFW-B nrPDB 117 6e-27 2EKL-A nrPDB 112 2e-25 4XYG-A nrPDB 112 3e-25 3KB6-A nrPDB 110 6e-25 2GO1-A nrPDB 110 7e-25 6ABI-A nrPDB 110 1e-24 3JTM-A nrPDB 110 1e-24 3GG9-A nrPDB 110 1e-24 3EVT-A nrPDB 109 1e-24 6D4C-A nrPDB 109 1e-24 3WR5-A nrPDB 108 3e-24 5Z1Z-A nrPDB 106 1e-23 4S1V-D nrPDB 105 4e-23 5MH6-A nrPDB 103 8e-23 4CUK-A nrPDB 101 4e-22 3FN4-A nrPDB 101 4e-22 6ABJ-A nrPDB 98 5e-21 3HG7-A nrPDB 98 6e-21 2PA3-A nrPDB 97 8e-21 2W2L-A nrPDB 95 4e-20 1DXY-A nrPDB 91 5e-19 1HL3-A nrPDB 91 5e-19 4HY3-A nrPDB 90 1e-18 4XA8-A nrPDB 89 2e-18 2OME-A nrPDB 89 3e-18 4PRK-A nrPDB 88 5e-18 1J49-A nrPDB 85 5e-17 3K5P-A nrPDB 84 1e-16 2DLD-A nrPDB 83 2e-16 5TSD-A nrPDB 82 5e-16 2YQ5-A nrPDB 81 6e-16 1XDW-A nrPDB 81 7e-16 3KBO-A nrPDB 80 1e-15 4XKJ-A nrPDB 78 7e-15 4N18-A nrPDB 77 1e-14 4WEQ-A nrPDB 73 2e-13 5C5I-A nrPDB 70 9e-13 3OET-A nrPDB 64 7e-11 5DT9-A nrPDB 63 1e-10 3GVX-A nrPDB 63 2e-10 1QP8-A nrPDB 56 2e-08 4NFY-A nrPDB 49 3e-06 2O4C-A nrPDB 49 3e-06 3AK5-A nrPDB 34 0.11 3NJ4-A nrPDB 33 0.19 5U5G-A nrPDB 32 0.31 5H82-A nrPDB 32 0.48 3G1U-A nrPDB 30 1.2 6HBE-A nrPDB 30 1.8 3PEF-A nrPDB 30 1.9 4OQZ-A nrPDB 29 2.1 1QB4-A nrPDB 29 2.6 1GPJ-A nrPDB 29 2.9 5EK8-A nrPDB 29 3.0 2L9N-A nrPDB 29 3.1 5G6R-A nrPDB 29 3.5 4E21-A nrPDB 29 3.6 4YPO-A nrPDB 29 3.6 4RG3-A nrPDB 28 4.1 5OCM-A nrPDB 28 4.7 3H9U-A nrPDB 28 4.9 5UKB-D nrPDB 28 5.5 4D3S-A nrPDB 27 9.8 >2WWR-A nrPDB Length = 330 Score = 672 bits (1733), Expect = 0.0, Method: Compositional matrix adjust. Identities = 328/328 (100%), Positives = 328/328 (100%) Query: 1 MRPVRLMKVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLS 60 MRPVRLMKVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLS Sbjct: 3 MRPVRLMKVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLS 62 Query: 61 DHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLL 120 DHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLL Sbjct: 63 DHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLL 122 Query: 121 TTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRF 180 TTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRF Sbjct: 123 TTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRF 182 Query: 181 LYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVF 240 LYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVF Sbjct: 183 LYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVF 242 Query: 241 INISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHR 300 INISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHR Sbjct: 243 INISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHR 302 Query: 301 TRNTMSLLAANNLLAGLRGEPMPSELKL 328 TRNTMSLLAANNLLAGLRGEPMPSELKL Sbjct: 303 TRNTMSLLAANNLLAGLRGEPMPSELKL 330 >5AOV-A nrPDB Length = 336 Score = 223 bits (568), Expect = 8e-59, Method: Compositional matrix adjust. Identities = 132/328 (40%), Positives = 190/328 (57%), Gaps = 13/328 (3%) Query: 1 MRPVRLMKVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLS 60 M+P KVF+TR IP G L + EV + + IP ++L V L+ +LS Sbjct: 1 MKP----KVFITRAIPENGINMLEEEFEVEVWE--EEREIPREKLLEKVKDVDALVTMLS 54 Query: 61 DHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLL 120 + +D+ + + A L++++ +VG D++ ++E +RGI V TPDVLT+ TA+ A +LLL Sbjct: 55 ERIDQEVFENA-PRLRIVANYAVGYDNIDVEEATRRGIYVTNTPDVLTNATADHAFALLL 113 Query: 121 TTCRRLPEAIEEVKNGGWT----SWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFG 176 T R + + + V++G W +W P W GY L T+GI+G GRIGQAIARR K F Sbjct: 114 ATARHVVKGDKFVRSGEWKRKGIAWHPKWFLGYELYGKTIGIVGFGRIGQAIARRAKGFN 173 Query: 177 VQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKE 236 + R LY R + + E AE+ E+ +SDF+++A LT T + N++ + MK Sbjct: 174 M-RILYYSRTRKSQAEKELGAEYRPLEEVLKESDFVILAVPLTKETMYMINEERLKLMKP 232 Query: 237 TAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGS 296 TA+ +NI+RG VV+ L +AL G IA AGLDV EP N L +L N V+ PHIGS Sbjct: 233 TAILVNIARGKVVDTKALIKALKEGWIAGAGLDVFEEEPY-YNEELFSLDNVVLTPHIGS 291 Query: 297 ATHRTRNTMSLLAANNLLAGLRGEPMPS 324 AT R M+ L A NL+A RGE P+ Sbjct: 292 ATFEAREAMAELVARNLIAFKRGEIPPT 319 >6BII-A nrPDB Length = 333 Score = 211 bits (536), Expect = 5e-55, Method: Compositional matrix adjust. Identities = 141/328 (42%), Positives = 193/328 (58%), Gaps = 13/328 (3%) Query: 1 MRPVRLMKVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLS 60 M+P KV +TR IP G + L R EVE W+ + IP + L V L+ +LS Sbjct: 1 MKP----KVLITRAIPENG-IELLRE-HFEVEVWEHEHEIPREVLLEKVKDVDALVTMLS 54 Query: 61 DHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLL 120 + +D+ + DAA L++++ +VG D++ ++E KRGI V TPDVLTD TA+LA +LLL Sbjct: 55 EKIDREVFDAA-PRLRIVANYAVGYDNIDIEEATKRGIYVTNTPDVLTDATADLAWALLL 113 Query: 121 TTCRRLPEAIEEVKNGGWT----SWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFG 176 R + + + V++G W +W P GY + T+GI+G GRIGQAIA+R K FG Sbjct: 114 AAARHVVKGDKFVRSGEWKRRGIAWHPKMFLGYDVYGKTIGIVGFGRIGQAIAKRAKGFG 173 Query: 177 VQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKE 236 + R LYT R +PE E AEF EL +SDF+V+A LT T + N++ + MK Sbjct: 174 M-RILYTARSRKPEAEKELGAEFKPLEELLRESDFVVLAVPLTKETYHMINEERLRLMKP 232 Query: 237 TAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGS 296 TAV +N++RG VV+ L +AL G IAAAGLDV EP + L L N V+ PHIGS Sbjct: 233 TAVLVNVARGKVVDTKALIRALKEGWIAAAGLDVFEEEPY-YDEELFALDNVVLTPHIGS 291 Query: 297 ATHRTRNTMSLLAANNLLAGLRGEPMPS 324 AT R M+ L A NL+A GE P+ Sbjct: 292 ATFGAREGMAELVAKNLIAFKNGEVPPT 319 >2DBZ-A nrPDB Length = 334 Score = 203 bits (516), Expect = 1e-52, Method: Compositional matrix adjust. Identities = 142/328 (43%), Positives = 194/328 (59%), Gaps = 13/328 (3%) Query: 1 MRPVRLMKVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLS 60 M+P KVF+TR IP G L + EVE W ++ IP + L + V L+ +LS Sbjct: 1 MKP----KVFITREIPEVGIKMLE--DEFEVEVWGDEKEIPREILLKKVKEVDALVTMLS 54 Query: 61 DHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLL 120 + +DK + + A L++++ +VG D++ ++E KRGI V TPDVLTD TA+LA +LLL Sbjct: 55 ERIDKEVFENA-PKLRIVANYAVGYDNIDIEEATKRGIYVTNTPDVLTDATADLAFALLL 113 Query: 121 TTCRRLPEAIEEVKNGGW----TSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFG 176 T R + + V++G W +W P W GY + T+GIIGLGRIGQAIA+R K F Sbjct: 114 ATARHVVKGDRFVRSGEWKKRGVAWHPKWFLGYDVYGKTIGIIGLGRIGQAIAKRAKGFN 173 Query: 177 VQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKE 236 + R LY R + E E AEF +L +SDF+V+A LT T L N++ + MK+ Sbjct: 174 M-RILYYSRTRKEEVERELNAEFKPLEDLLRESDFVVLAVPLTRETYHLINEERLKLMKK 232 Query: 237 TAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGS 296 TA+ INI+RG VV+ + L +AL G IA AGLDV EP N L L N V+ PHIGS Sbjct: 233 TAILINIARGKVVDTNALVKALKEGWIAGAGLDVFEEEPY-YNEELFKLDNVVLTPHIGS 291 Query: 297 ATHRTRNTMSLLAANNLLAGLRGEPMPS 324 A+ R M+ L A NL+A RGE P+ Sbjct: 292 ASFGAREGMAELVAKNLIAFKRGEIPPT 319 >2CUK-A nrPDB Length = 311 Score = 194 bits (492), Expect = 5e-50, Method: Compositional matrix adjust. Identities = 133/319 (41%), Positives = 187/319 (58%), Gaps = 12/319 (3%) Query: 7 MKVFVTRRIPAEGRVAL-ARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLSDHVDK 65 M+V VTR +P + L R + EV + +P EL + V GA GL+ + D +D Sbjct: 1 MRVLVTRTLPGKALDRLRERGLEVEVHRGLF---LPKAELLKRVEGAVGLIPTVEDRIDA 57 Query: 66 RILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRR 125 ++D A LKVI+ SVG+DH+ L+ ++RGIRV +TP VLT+ TA+L ++LLL RR Sbjct: 58 EVMDRA-KGLKVIACYSVGVDHVDLEAARERGIRVTHTPGVLTEATADLTLALLLAVARR 116 Query: 126 LPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGR 185 + E ++G W +W P L G L T+G++G+GRIGQA+A+R FG+ R +Y R Sbjct: 117 VVEGAAYARDGLWKAWHPELLLGLDLQGLTLGLVGMGRIGQAVAKRALAFGM-RVVYHAR 175 Query: 186 QPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISR 245 P+P F+S EL ++D + + LTP T L N++ MK A+ +N +R Sbjct: 176 TPKP-----LPYPFLSLEELLKEADVVSLHTPLTPETHRLLNRERLFAMKRGAILLNTAR 230 Query: 246 GDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTM 305 G +V+ + L +AL G + AGLDVT PEPLP HPL L N VI PHIGSA TR M Sbjct: 231 GALVDTEALVEAL-RGHLFGAGLDVTDPEPLPPGHPLYALPNAVITPHIGSAGRTTRERM 289 Query: 306 SLLAANNLLAGLRGEPMPS 324 + +A NLLA L G P+ Sbjct: 290 AEVAVENLLAVLEGREPPN 308 >4G2N-A nrPDB Length = 345 Score = 181 bits (459), Expect = 4e-46, Method: Compositional matrix adjust. Identities = 114/304 (37%), Positives = 162/304 (53%), Gaps = 6/304 (1%) Query: 6 LMKVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLSDHVDK 65 + K F+ RR L + D EV D+ + + GA L ++ + Sbjct: 28 IQKAFLCRRFTPAIEAELRQRFDLEVNLEDT--VLTPSGIASRAHGAEVLFVTATEAITA 85 Query: 66 RILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRR 125 ++ LK I+T+SVG DH+ + + GI+V +TPDVL+D AE+A+ L+L CRR Sbjct: 86 EVIRKLQPGLKTIATLSVGYDHIDMAAARSLGIKVLHTPDVLSDACAEIAMLLVLNACRR 145 Query: 126 LPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGR 185 EA V++G W W P L G GLT +GI G+GRIG+AIA R + FG+ ++ Sbjct: 146 GYEADRMVRSGSWPGWGPTQLLGMGLTGRRLGIFGMGRIGRAIATRARGFGLA--IHYHN 203 Query: 186 QPRPEEAAEFQAEFVSTPE-LAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINIS 244 + R A E A + T + L SD ++A P +G + D K+ E AV INIS Sbjct: 204 RTRLSHALEEGAIYHDTLDSLLGASDIFLIAAPGRPELKGFLDHDRIAKIPEGAVVINIS 263 Query: 245 RGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNT 304 RGD++N D L +AL S + AAGLDV + EP + +L N + PHIGSATH TR+ Sbjct: 264 RGDLINDDALIEALRSKHLFAAGLDVFANEP-AIDPRYRSLDNIFLTPHIGSATHETRDA 322 Query: 305 MSLL 308 M L Sbjct: 323 MGWL 326 >1GDH-A nrPDB Length = 320 Score = 172 bits (435), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 109/314 (34%), Positives = 162/314 (51%), Gaps = 7/314 (2%) Query: 8 KVFVTRRIPAEGRVALARAADCEVEQWDSDEP-IPAKELERGVAGAHGLLCLLSDHVDKR 66 K+ +T +P A+ARA + D+P I E+ LL L++ K Sbjct: 3 KILITWPLP---EAAMARARESYDVIAHGDDPKITIDEMIETAKSVDALLITLNEKCRKE 59 Query: 67 ILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRL 126 ++D N+K IST S+G DH+ LD K RGI+VG P +T TAE+A+ LLL + RR Sbjct: 60 VIDRIPENIKCISTYSIGFDHIDLDACKARGIKVGNAPHGVTVATAEIAMLLLLGSARRA 119 Query: 127 PEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQ 186 E + ++ W W+PL L G L T+GI G G IGQA+A+R + F + + + Sbjct: 120 GEGEKMIRTRSWPGWEPLELVGEKLDNKTLGIYGFGSIGQALAKRAQGFDMDIDYFDTHR 179 Query: 187 PRPEEAAEFQAEFV-STPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISR 245 + A +QA F S L + S F + TP T NK + + + A+ +N +R Sbjct: 180 ASSSDEASYQATFHDSLDSLLSVSQFFSLNAPSTPETRYFFNKATIKSLPQGAIVVNTAR 239 Query: 246 GDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTM 305 GD+V+ + + AL +G++A AG DV + EP N L N + PHIGSA + R M Sbjct: 240 GDLVDNELVVAALEAGRLAYAGFDVFAGEP-NINEGYYDLPNTFLFPHIGSAATQAREDM 298 Query: 306 SLLAANNLLAGLRG 319 + AN+L+ L G Sbjct: 299 A-HQANDLIDALFG 311 >3BA1-A nrPDB Length = 333 Score = 166 bits (421), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 100/259 (38%), Positives = 142/259 (54%), Gaps = 8/259 (3%) Query: 64 DKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTC 123 D ++DA L+++S+ SVG+D + L + +++G+RV TPDVLTD A+LA+ L+L Sbjct: 78 DAELIDAL-PKLEIVSSFSVGLDKVDLIKCEEKGVRVTNTPDVLTDDVADLAIGLILAVL 136 Query: 124 RRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYT 183 RR+ E + V+ G W + + VGIIGLGRIG A+A R + F Y Sbjct: 137 RRICECDKYVRRGAWKFGD--FKLTTKFSGKRVGIIGLGRIGLAVAERAEAFDCP-ISYF 193 Query: 184 GRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINI 243 R +P + V ELA+ SD +VVAC LTP T + N++ + V INI Sbjct: 194 SRSKKPNTNYTYYGSVV---ELASNSDILVVACPLTPETTHIINREVIDALGPKGVLINI 250 Query: 244 SRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRN 303 RG V++ +L AL G++ AGLDV EP L L+N V+LPH+GS T TR Sbjct: 251 GRGPHVDEPELVSALVEGRLGGAGLDVFEREP-EVPEKLFGLENVVLLPHVGSGTVETRK 309 Query: 304 TMSLLAANNLLAGLRGEPM 322 M+ L NL A G+P+ Sbjct: 310 VMADLVVGNLEAHFSGKPL 328 >2D0I-A nrPDB Length = 333 Score = 149 bits (376), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 106/332 (31%), Positives = 169/332 (50%), Gaps = 22/332 (6%) Query: 1 MRPVRLMKVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAH-GLLCLL 59 MRP KV V ++ E L + AD E+ + S E + +GV G G++ Sbjct: 1 MRP----KVGVLLKMKREALEELKKYADVEIILYPSGEEL------KGVIGRFDGIIVSP 50 Query: 60 SDHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLL 119 + + + +L+ A LKVIS S G D++ L+E KRGI V +L++ AE V L+ Sbjct: 51 TTKITREVLENA-ERLKVISCHSAGYDNIDLEEATKRGIYVTKVSGLLSEAVAEFTVGLI 109 Query: 120 LTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQS----TVGIIGLGRIGQAIARRLKPF 175 + R++ A + ++ G W S +W G+ +S VGI+G+G IG+AIARRL PF Sbjct: 110 INLMRKIHYADKFIRRGEWESHAKIW-TGFKRIESLYGKKVGILGMGAIGKAIARRLIPF 168 Query: 176 GVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMK 235 GV+ + Y R + E +A ++ EL +SD +++A LT T + N++ +K+ Sbjct: 169 GVKLY-YWSRHRKVNVEKELKARYMDIDELLEKSDIVILALPLTRDTYHIINEERVKKL- 226 Query: 236 ETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLK-NCVILPHI 294 E +NI RG +V++ + +A+ GK+ DV EP+ H L + V+ PH Sbjct: 227 EGKYLVNIGRGALVDEKAVTEAIKQGKLKGYATDVFEKEPV-REHELFKYEWETVLTPHY 285 Query: 295 GSATHRTRNTMSLLAANNLLAGLRGEPMPSEL 326 + + A NLL LRGE +P +L Sbjct: 286 AGLALEAQEDVGFRAVENLLKVLRGE-VPEDL 316 >4EBF-A nrPDB Length = 334 Score = 139 bits (349), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 100/322 (31%), Positives = 152/322 (47%), Gaps = 11/322 (3%) Query: 6 LMKVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLSDHVDK 65 L K+ +T R+ E + A CE+ +D + +E+ R A ++ + D VD Sbjct: 3 LPKLVITHRVHEE--ILQLLAPHCELITNQTDSTLTREEILRRCRDAQAMMAFMPDRVDA 60 Query: 66 RILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRR 125 L A L+VI G D+ +D RG+ + + PD+LT TAELA+ L + R Sbjct: 61 DFLQAC-PELRVIGCALKGFDNFDVDACTARGVWLTFVPDLLTVPTAELAIGLAVGLGRH 119 Query: 126 LPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGR 185 L A V++G + W+P + G GL +TVG +G+G IG A+A RL+ +G + + Sbjct: 120 LRAADAFVRSGQFRGWQPRFY-GTGLDNATVGFLGMGAIGLAMADRLQGWGATLQYHAAK 178 Query: 186 QPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISR 245 + V+ EL A SDFI++A L T L N + ++ A+ +N R Sbjct: 179 ALDTQTEQRLGLRQVACSELFASSDFILLALPLNADTLHLVNAELLALVRPGALLVNPCR 238 Query: 246 GDVVNQDDLYQALASGKIAAAGLDVTSPE-------PLPTNHPLLTLKNCVILPHIGSAT 298 G VV++ + AL G++ DV E P + LL N + PHIGSA Sbjct: 239 GSVVDEAAVLAALERGQLGGYAADVFEMEDWARADRPQQIDPALLAHPNTLFTPHIGSAV 298 Query: 299 HRTRNTMSLLAANNLLAGLRGE 320 R + AA N+L L GE Sbjct: 299 RAVRLEIERCAAQNILQALAGE 320 >1WWK-A nrPDB Length = 307 Score = 138 bits (347), Expect = 4e-33, Method: Compositional matrix adjust. Identities = 92/257 (35%), Positives = 142/257 (55%), Gaps = 5/257 (1%) Query: 63 VDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTT 122 V +R++++A LKVI+ VG+D++ ++ K++GI V P + + AELAV L+ + Sbjct: 56 VTRRVIESA-PKLKVIARAGVGLDNIDVEAAKEKGIEVVNAPAASSRSVAELAVGLMFSV 114 Query: 123 CRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLY 182 R++ A +++ G W + + G L T+GIIG GRIG +A+ G+ LY Sbjct: 115 ARKIAFADRKMREGVWAKKEAM---GIELEGKTIGIIGFGRIGYQVAKIANALGMNILLY 171 Query: 183 TGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFIN 242 P E A E +FV L +SD + + L +T L N++ + MK+TA+ IN Sbjct: 172 DP-YPNEERAKEVNGKFVDLETLLKESDVVTIHVPLVESTYHLINEERLKLMKKTAILIN 230 Query: 243 ISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTR 302 SRG VV+ + L +AL G IA AGLDV EPLP +HPL N V+ PHIG++T + Sbjct: 231 TSRGPVVDTNALVKALKEGWIAGAGLDVFEEEPLPKDHPLTKFDNVVLTPHIGASTVEAQ 290 Query: 303 NTMSLLAANNLLAGLRG 319 + A ++ L+G Sbjct: 291 ERAGVEVAEKVVKILKG 307 >5TX7-A nrPDB Length = 327 Score = 136 bits (343), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 93/289 (32%), Positives = 143/289 (49%), Gaps = 15/289 (5%) Query: 41 PAKELERGVAGAHGLLCLLSDHV--DKRILDAAGANLKVISTMSVGIDHLALDEIKKRGI 98 P+ ++ AGAH +L++ V D L A L+ +S ++ G D + + GI Sbjct: 35 PSDKIIERAAGAH---VVLTNKVPLDMSALQAL-PGLRFVSVLATGYDKVDVAAAGVLGI 90 Query: 99 RVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQ----- 153 V P TD+ A+ +LLL CRR ++ G WT P W C + TQ Sbjct: 91 PVSNVPGYGTDSVAQHVFALLLELCRRTALHDHRIRAGAWTQ-SPDW-CFWDSTQEELTG 148 Query: 154 STVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIV 213 T+GI+G G G+ + R G+ Y R + F E V EL +D + Sbjct: 149 KTMGIVGFGNTGRRVGRIANALGMNVIAYAPRSRFDPDYRPF--EHVGLDELFTSADVVS 206 Query: 214 VACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSP 273 + C LTP TEGL + M+ + IN +RG ++++ + +AL SG++A AGLDV S Sbjct: 207 LHCPLTPETEGLVDARRLASMRPGSYLINTARGPLLDERAVAEALDSGRLAGAGLDVLSQ 266 Query: 274 EPLPTNHPLLTLKNCVILPHIGSATHRTRNTMSLLAANNLLAGLRGEPM 322 EP ++PLL+ KNC+I PH+ A+ R T+ A N+ + + G P+ Sbjct: 267 EPPAADNPLLSAKNCLITPHLAWASRTARRTLMDSTAANIRSFIEGTPV 315 >4DGS-A nrPDB Length = 340 Score = 136 bits (343), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 86/254 (33%), Positives = 132/254 (51%), Gaps = 6/254 (2%) Query: 74 NLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEV 133 +L +I+ VG D + L ++R I V TP VL D A+L ++L+L RR+ + V Sbjct: 93 SLGIIAINGVGTDKVDLARARRRNIDVTTTPGVLADDVADLGIALMLAVLRRVGDGDRLV 152 Query: 134 KNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAA 193 + G W + + L L G+ +G++GLG+IG+A+A R + FG+ + R + Sbjct: 153 REGRWAAGEQLPL-GHSPKGKRIGVLGLGQIGRALASRAEAFGMSVRYWN----RSTLSG 207 Query: 194 EFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDD 253 S +LA SD + V + + AT+ + + Q + + +N++RG+VV++D Sbjct: 208 VDWIAHQSPVDLARDSDVLAVCVAASAATQNIVDASLLQALGPEGIVVNVARGNVVDEDA 267 Query: 254 LYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTMSLLAANNL 313 L +AL SG IA AGLDV EP T N V++PH GSAT TR M L NL Sbjct: 268 LIEALKSGTIAGAGLDVFVNEP-AIRSEFHTTPNTVLMPHQGSATVETRMAMGKLVLANL 326 Query: 314 LAGLRGEPMPSELK 327 A GE P+ + Sbjct: 327 AAHFAGEKAPNTVN 340 >5UOG-A nrPDB Length = 344 Score = 135 bits (341), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 96/244 (39%), Positives = 127/244 (52%), Gaps = 9/244 (3%) Query: 74 NLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEV 133 +L++++ VG D + + RGI V TPDVLT+ A+ A+ LLL T R LP+A + + Sbjct: 85 SLEIVANFGVGYDGVDVSRAAARGIVVTNTPDVLTEEVADTAIGLLLNTLRLLPQAEQWL 144 Query: 134 KNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAA 193 + G W L L TVG+ GLGRIG AIARRL+ FGV Y R PR Sbjct: 145 RQGRWVREGAFPLSPLSLRGRTVGLFGLGRIGLAIARRLEAFGVS-IAYHTRTPREGLGF 203 Query: 194 EFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDD 253 + V +A D ++V T +T N D + V IN+ RG V++ Sbjct: 204 TYHPTLVG---MAEAVDTLIVIVPGTASTLKAVNADVLSALGPKGVLINVGRGSTVDEAA 260 Query: 254 LYQALASGKIAAAGLDVTSPEPLPTNHP--LLTLKNCVILPHIGSATHRTRNTMSLLAAN 311 L AL +G IA AGLDV EP N P LL+ N +LPH+ SA+ TRN MS L + Sbjct: 261 LVTALQNGTIAGAGLDVFENEP---NVPEALLSFPNVSLLPHVASASVVTRNAMSDLVVD 317 Query: 312 NLLA 315 NL A Sbjct: 318 NLKA 321 >2G76-A nrPDB Length = 335 Score = 135 bits (339), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 84/268 (31%), Positives = 146/268 (54%), Gaps = 10/268 (3%) Query: 38 EPIPAKELERGVAGAHGLLCLLSDHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRG 97 + + +EL + GL+ + V +++AA L+V+ G+D++ L+ ++G Sbjct: 54 QNLSKEELIAELQDCEGLIVRSATKVTADVINAA-EKLQVVGRAGTGVDNVDLEAATRKG 112 Query: 98 IRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVG 157 I V TP+ + + AEL +++ R++P+A +K+G W K + G L T+G Sbjct: 113 ILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWERKKFM---GTELNGKTLG 169 Query: 158 IIGLGRIGQAIARRLKPFGVQRFLYTGRQP--RPEEAAEFQAEFVSTPELAAQSDFIVVA 215 I+GLGRIG+ +A R++ FG++ Y P PE +A F + + E+ DFI V Sbjct: 170 ILGLGRIGREVATRMQSFGMKTIGY---DPIISPEVSASFGVQQLPLEEIWPLCDFITVH 226 Query: 216 CSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEP 275 L P+T GL N + F + K+ +N +RG +V++ L +AL SG+ A A LDV + EP Sbjct: 227 TPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEP 286 Query: 276 LPTNHPLLTLKNCVILPHIGSATHRTRN 303 P + L+ +N + PH+G++T ++ Sbjct: 287 -PRDRALVDHENVISCPHLGASTKEAQS 313 >3DC2-A nrPDB Length = 529 Score = 135 bits (339), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 93/277 (33%), Positives = 145/277 (52%), Gaps = 6/277 (2%) Query: 52 AHGLLCLLSDHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTT 111 A LL + VD +L AA LK+++ VG+D++ +D RG+ V P + Sbjct: 45 ADALLVRSATTVDAEVL-AAAPKLKIVARAGVGLDNVDVDAATARGVLVVNAPTSNIHSA 103 Query: 112 AELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARR 171 AE A++LLL R++P A ++ +WK G + TVG++GLGRIGQ +A+R Sbjct: 104 AEHALALLLAASRQIPAADASLRE---HTWKRSSFSGTEIFGKTVGVVGLGRIGQLVAQR 160 Query: 172 LKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFF 231 + FG Y P AA+ E +S +L A++DFI V TP T GL +K+ Sbjct: 161 IAAFGAYVVAYD-PYVSPARAAQLGIELLSLDDLLARADFISVHLPKTPETAGLIDKEAL 219 Query: 232 QKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVIL 291 K K + +N +RG +V++ L A+ G + AAGLDV + EP T+ PL L V+ Sbjct: 220 AKTKPGVIIVNAARGGLVDEAALADAITGGHVRAAGLDVFATEPC-TDSPLFELAQVVVT 278 Query: 292 PHIGSATHRTRNTMSLLAANNLLAGLRGEPMPSELKL 328 PH+G++T ++ A ++ L GE +P + + Sbjct: 279 PHLGASTAEAQDRAGTDVAESVRLALAGEFVPDAVNV 315 >4ZGS-A nrPDB Length = 386 Score = 122 bits (307), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 92/311 (29%), Positives = 142/311 (45%), Gaps = 27/311 (8%) Query: 38 EPIPAKELERGVAGAHGLLCLLSDHVDKRIL-DAAGANLKVISTMSVGIDHLALDEIKKR 96 EP K+ + G + ++D D ++ + A A +K+I+ G D + L + Sbjct: 65 EPPLDKDTAQLARGYDVAVLFVNDRADASVIKELAKAGVKLIALRCAGFDRVDLHACAEH 124 Query: 97 GIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTV 156 G+RV P ++ AE AV+L+ R L +A V+ G ++ L G + V Sbjct: 125 GVRVVRVPTYSPESVAEHAVALIFALNRHLTDAYIRVRMGNYSLS---GLVGVEMRHKVV 181 Query: 157 GIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQA-EFVSTPELAAQSDFIVVA 215 G++G G IGQ AR LK G + F Y +P A E +VS EL A SD + + Sbjct: 182 GVVGTGAIGQQAARILKGIGCKVFAY---DIKPNPAVEAMGIPYVSLDELLAMSDIVTLH 238 Query: 216 CSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEP 275 C L P+T L NK+ QKMK+ + IN+SRG +++ L+ AL SG+I A GLDV E Sbjct: 239 CPLLPSTRQLINKESIQKMKKGVMLINVSRGGLIDSAALFDALESGQIGALGLDVYENEG 298 Query: 276 --LPTNH-----------------PLLTLKNCVILPHIGSATHRTRNTMSLLAANNLLAG 316 +H LL+ ++ PH T N + N+ Sbjct: 299 GLFFVDHTKFDPSVRMQKWDRQFRTLLSYPQVLVTPHTAFLTEEALNNICTTTIQNIADY 358 Query: 317 LRGEPMPSELK 327 + P+ +E+K Sbjct: 359 VLDRPLGNEVK 369 >6IH4-A nrPDB Length = 338 Score = 122 bits (307), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 95/295 (32%), Positives = 142/295 (48%), Gaps = 13/295 (4%) Query: 38 EPIPAKELERGVAGAHGLLCLLSDHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRG 97 E +P E+ A L+ + D +D L+ L+VI G D+ ++ + G Sbjct: 32 ETLPRSEVIARAKDADALMAFMPDSIDSAFLEEC-PKLRVIGAALKGYDNFDVNACTRHG 90 Query: 98 IRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVG 157 + + PD+LT TAEL + LLL R + E ++++G + W+P L G GLT T+G Sbjct: 91 VWLTIVPDLLTIPTAELTIGLLLGLTRHMLEGDRQIRSGHFQGWRPT-LYGSGLTGKTLG 149 Query: 158 IIGLGRIGQAIARRLKPFGVQRFLYTGRQP-RPEEAAEFQAEFVSTPELAAQSDFIVVAC 216 I G+G +G+AIA+RL F + LY P E+ + + V+ EL + D++V Sbjct: 150 IRGMGAVGRAIAQRLAGFEMN-LLYCDEIPLNAEQEKAWHVQRVTLDELLEKCDYVVPMV 208 Query: 217 SLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPL 276 + T L + KMK + IN RG VV+++ + ALASGK+A DV E Sbjct: 209 PMAAETLHLIDATALAKMKTGSYLINACRGSVVDENAVIAALASGKLAGYAADVFEMEEW 268 Query: 277 -----PTNHPLLTLKN---CVILPHIGSATHRTRNTMSLLAANNLLAGLRGE-PM 322 P P L N PH+GSA R + AA N++ L GE PM Sbjct: 269 IRADRPQAIPKALLDNTAQTFFTPHLGSAVKEVRLEIERQAAMNIIQALAGEKPM 323 >4LSW-A nrPDB Length = 318 Score = 122 bits (307), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 86/258 (33%), Positives = 129/258 (50%), Gaps = 5/258 (1%) Query: 65 KRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCR 124 R L A NL++IS VG D + L ++RGI+V TPDVLT A+L V+++L R Sbjct: 58 SRALIEACPNLELISVYGVGYDAVDLAACRERGIQVTNTPDVLTGDVADLGVAMMLAQSR 117 Query: 125 RLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTG 184 + A ++G W + + L+ + G++GLGRIG +ARRL F +Q Y+ Sbjct: 118 GIIGAETWARSGKWAA-EGLYPLKRRVFGRRAGVLGLGRIGFEVARRLAGFDMQ-ISYSD 175 Query: 185 RQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINIS 244 P+ E T LA DF+ V + + AT + +D + + + INIS Sbjct: 176 IAPKSYAPDWTFVEDAVT--LARDVDFLFVTLAASAATRHIVGRDVIEALGPEGMLINIS 233 Query: 245 RGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNT 304 R ++++ L ALA G++ +A LDV EP + L N ++ PH S T TR Sbjct: 234 RASNIDEEALIAALADGRLGSAALDVFEGEP-NFDPRFRDLPNVLLQPHHASGTIETRKA 292 Query: 305 MSLLAANNLLAGLRGEPM 322 M L +NL A G P+ Sbjct: 293 MGQLLRDNLTAHFAGSPL 310 >3WNV-A nrPDB Length = 330 Score = 119 bits (298), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 86/258 (33%), Positives = 140/258 (54%), Gaps = 7/258 (2%) Query: 64 DKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTC 123 D+ ++ A ++K I G D++ +D + GI + TP + + TA++A+ L++ Sbjct: 68 DRELISALPKSVKYICHNGAGYDNIDVDAATEAGIAISSTPIAVNNATADVAIFLMIGAL 127 Query: 124 RRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYT 183 R+ I ++ G W L G+ T+GI+G+G IG+ +ARR + FG+ +Y Sbjct: 128 RQAYVPITAIRAGEWHGKTTL---GHDPNGKTLGILGMGGIGREVARRARAFGMN-IIYH 183 Query: 184 GRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINI 243 R P E E A++VS EL AQSD + +L +T + + KMK+ V +N Sbjct: 184 NRNKLPPEL-EDGAKYVSFDELLAQSDVFSLNLALNASTRHIIGEKELAKMKDGVVIVNT 242 Query: 244 SRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRN 303 +RG ++++ L +AL SGK+A+ GLDV EP LL ++LPHIG+ T+ T+ Sbjct: 243 ARGALIDEKALVRALESGKVASVGLDVYENEP-QVEPGLLNNPRAMLLPHIGTMTYETQK 301 Query: 304 TMSLLAANNLLAGL-RGE 320 M LL NNL + + +GE Sbjct: 302 EMELLVLNNLRSAIEKGE 319 >5OFW-B nrPDB Length = 223 Score = 117 bits (293), Expect = 6e-27, Method: Compositional matrix adjust. Identities = 69/203 (33%), Positives = 114/203 (56%), Gaps = 9/203 (4%) Query: 103 TPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLG 162 TP+ + + AEL +++ R++P+A +K+G W K + G L T+GI+GLG Sbjct: 6 TPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWERKKFM---GTELNGKTLGILGLG 62 Query: 163 RIGQAIARRLKPFGVQRFLYTGRQP--RPEEAAEFQAEFVSTPELAAQSDFIVVACSLTP 220 RIG+ +A R++ FG++ Y P PE +A F + + E+ DFI V L P Sbjct: 63 RIGREVATRMQSFGMKTIGY---DPIISPEVSASFGVQQLPLEEIWPLCDFITVHTPLLP 119 Query: 221 ATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNH 280 +T GL N + F + K+ +N +RG +V++ L +AL SG+ A A LDV + EP P + Sbjct: 120 STTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEP-PRDR 178 Query: 281 PLLTLKNCVILPHIGSATHRTRN 303 L+ +N + PH+G++T ++ Sbjct: 179 ALVDHENVISCPHLGASTKEAQS 201 >2EKL-A nrPDB Length = 313 Score = 112 bits (281), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 78/283 (27%), Positives = 138/283 (48%), Gaps = 10/283 (3%) Query: 39 PIPAKELERGVAGAHGLLCLLS-DHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRG 97 P +KE + G + ++ + S V K +++ G LK+I+ +G+D++ +E +KR Sbjct: 33 PEISKEELLNIIGNYDIIVVRSRTKVTKDVIEK-GKKLKIIARAGIGLDNIDTEEAEKRN 91 Query: 98 IRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVG 157 I+V Y P TD+ EL + L++ R++ ++ K+G + + L L G T+G Sbjct: 92 IKVVYAPGASTDSAVELTIGLMIAAARKMYTSMALAKSGIFKKIEGLELAG-----KTIG 146 Query: 158 IIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACS 217 I+G GRIG + G++ Y R E+A + A+ VS EL SD I + + Sbjct: 147 IVGFGRIGTKVGIIANAMGMKVLAYDILDIR-EKAEKINAKAVSLEELLKNSDVISLHVT 205 Query: 218 LTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLP 277 ++ + + + F+ MK+ + +N SR VN L + GK+ A DV EP Sbjct: 206 VSKDAKPIIDYPQFELMKDNVIIVNTSRAVAVNGKALLDYIKKGKVYAYATDVFWNEPPK 265 Query: 278 TNHPLLTLKN--CVILPHIGSATHRTRNTMSLLAANNLLAGLR 318 L LK+ ++ HIG+ T + ++ + NLL ++ Sbjct: 266 EEWELELLKHERVIVTTHIGAQTKEAQKRVAEMTTQNLLNAMK 308 >4XYG-A nrPDB Length = 391 Score = 112 bits (279), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 73/224 (32%), Positives = 107/224 (47%), Gaps = 10/224 (4%) Query: 80 TMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWT 139 T +G DH+ L+ K GI V AE AV ++L R + + + GGW Sbjct: 120 TAGIGSDHVDLNAAIKAGITVAEETFSNGICVAEHAVMMILALVRNYLPSHKIAEEGGWN 179 Query: 140 SWKPLWLC---GYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQ--PRPEEAAE 194 + C Y L VG + GRIG A+ RRLKPF V + YT R PR E Sbjct: 180 ----IADCVSRSYDLEGMHVGTVAAGRIGLAVLRRLKPFDV-KLHYTARHRSPRAIEDEL 234 Query: 195 FQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDL 254 + E+A D I + L PATE L N KM+ + +N +R ++ ++DD+ Sbjct: 235 GLTYHATAEEMAEVCDVISIHAPLYPATEHLFNAKVLNKMRHGSYLVNTARAEICDRDDI 294 Query: 255 YQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSAT 298 +AL SG++A DV P+P P NHP + + + PH+ ++ Sbjct: 295 VRALESGQLAGYAGDVWFPQPAPANHPWRNMPHNGMTPHMSGSS 338 >3KB6-A nrPDB Length = 334 Score = 110 bits (276), Expect = 6e-25, Method: Compositional matrix adjust. Identities = 85/290 (29%), Positives = 136/290 (46%), Gaps = 25/290 (8%) Query: 28 DCEVEQWDSD-EPIPAKELERGVAGAHGLLCLLSDHVDKRILDAAGANLKVISTMSVGID 86 D ++ + +D +P EL++ A + + D + + +L + LK+I T SVG D Sbjct: 22 DLSLKIYTTDVSKVPENELKK----AELISVFVYDKLTEELL-SKMPRLKLIHTRSVGFD 76 Query: 87 HLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWL 146 H+ LD KK+GI V + P ++ AE +++LT +RL + VK ++ + Sbjct: 77 HIDLDYCKKKGILVTHIPAYSPESVAEHTFAMILTLVKRLKRIEDRVKKLNFSQDSEIL- 135 Query: 147 CGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELA 206 L + T+G+IG GRIG +A FG++ Y + E+ E + S EL Sbjct: 136 -ARELNRLTLGVIGTGRIGSRVAMYGLAFGMKVLCYD--VVKREDLKEKGCVYTSLDELL 192 Query: 207 AQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAA 266 +SD I + T T + N++ MK+ IN +RG VV+ D LY+A GK + Sbjct: 193 KESDVISLHVPYTKETHHMINEERISLMKDGVYLINTARGKVVDTDALYRAYQRGKFSGL 252 Query: 267 GLDVTSPEPL------------PTNHPLLTL---KNCVILPHIGSATHRT 301 GLDV E + N +L L N +I PHI T ++ Sbjct: 253 GLDVFEDEEILILKKYTEGKATDKNLKILELACKDNVIITPHIAYYTDKS 302 >2GO1-A nrPDB Length = 401 Score = 110 bits (276), Expect = 7e-25, Method: Compositional matrix adjust. Identities = 74/234 (31%), Positives = 109/234 (46%), Gaps = 10/234 (4%) Query: 70 AAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEA 129 A NLK+ T +G DH+ L R + V + + AE V ++L+ R + Sbjct: 110 AKAKNLKLALTAGIGSDHVDLQSAIDRNVTVAEVTYCNSISVAEHVVMMILSLVRNYLPS 169 Query: 130 IEEVKNGGWTSWKPLWLC---GYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQ 186 E + GGW + C Y L VG + GRIG A+ RRL PF V YT R Sbjct: 170 HEWARKGGWN----IADCVSHAYDLEAMHVGTVAAGRIGLAVLRRLAPFDVH-LHYTDRH 224 Query: 187 PRPEEA-AEFQAEFVSTPE-LAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINIS 244 PE E + +T E + D + + C L P TE + N + + K A +N + Sbjct: 225 RLPESVEKELNLTWHATREDMYPVCDVVTLNCPLHPETEHMINDETLKLFKRGAYIVNTA 284 Query: 245 RGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSAT 298 RG + ++D + +AL SG++A DV P+P P +HP T+ + PHI T Sbjct: 285 RGKLCDRDAVARALESGRLAGYAGDVWFPQPAPKDHPWRTMPYNGMTPHISGTT 338 >6ABI-A nrPDB Length = 358 Score = 110 bits (274), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 81/293 (27%), Positives = 143/293 (48%), Gaps = 26/293 (8%) Query: 52 AHGLLC-LLSDHVDKRILDAAGAN-LKVISTMSVGIDHLALDEIKKRG--IRV-GYTPDV 106 + ++C +D+++K +D N +K+++ G ++++L ++ +R +RV Y+P Sbjct: 70 GYDVVCGFANDNINKETIDIMAENGIKLLAMRCAGFNNVSLKDVNERFKVVRVPAYSPHA 129 Query: 107 LTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQ 166 + AE V L+L R++ +A + G ++ L G L + T GIIG G+IGQ Sbjct: 130 I----AEYTVGLILAVNRKINKAYVRTREGNFSIN---GLMGIDLYEKTAGIIGTGKIGQ 182 Query: 167 AIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLC 226 + + L+ F ++ Y P + A E E+VS EL A SD I + C LT T+ + Sbjct: 183 ILIKILRGFDMKVIAYD-LFPNQKVADELGFEYVSLDELYANSDIISLNCPLTKDTKYMI 241 Query: 227 NKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVT-----------SPEP 275 N+ KMK+ + +N RG +++ DL +AL KI A LDV S + Sbjct: 242 NRRSMLKMKDGVILVNTGRGMLIDSADLVEALKDKKIGAVALDVYEEEENYFFEDKSTQV 301 Query: 276 LPTN--HPLLTLKNCVILPHIGSATHRTRNTMSLLAANNLLAGLRGEPMPSEL 326 + + LL+ N +I H T +++ NN+ + G P+ +E+ Sbjct: 302 IEDDILGRLLSFYNVLITSHQAYFTKEAVGAITVTTLNNIKDFVEGRPLVNEV 354 >3JTM-A nrPDB Length = 351 Score = 110 bits (274), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 71/247 (28%), Positives = 110/247 (44%), Gaps = 2/247 (0%) Query: 80 TMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWT 139 T +G DH+ L G+ V + AE + +L R +V G W Sbjct: 92 TAGIGSDHIDLQAAAAAGLTVAEVTGSNVVSVAEDELMRILILMRNFVPGYNQVVKGEWN 151 Query: 140 SWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEF 199 + Y L T+G +G GRIG+ + +RLKPFG + Q PE E A+F Sbjct: 152 V-AGIAYRAYDLEGKTIGTVGAGRIGKLLLQRLKPFGCNLLYHDRLQMAPELEKETGAKF 210 Query: 200 VST-PELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQAL 258 V E+ + D IV+ LT T G+ NK+ K+K+ + +N +RG ++ + + A+ Sbjct: 211 VEDLNEMLPKCDVIVINMPLTEKTRGMFNKELIGKLKKGVLIVNNARGAIMERQAVVDAV 270 Query: 259 ASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTMSLLAANNLLAGLR 318 SG I DV P+P P +HP + N + PH T + + + L + Sbjct: 271 ESGHIGGYSGDVWDPQPAPKDHPWRYMPNQAMTPHTSGTTIDAQLRYAAGTKDMLERYFK 330 Query: 319 GEPMPSE 325 GE P+E Sbjct: 331 GEDFPTE 337 >3GG9-A nrPDB Length = 352 Score = 110 bits (274), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 70/216 (32%), Positives = 109/216 (50%), Gaps = 9/216 (4%) Query: 112 AELAVSLLLTTCRRLPEAIEEVKNGGW-------TSWKPLWLCGYGLTQSTVGIIGLGRI 164 AEL +L++ RR+P+ + +K+G W T+ P + G L T+GI G G+I Sbjct: 112 AELTWALVMAAQRRIPQYVASLKHGAWQQSGLKSTTMPPNFGIGRVLKGQTLGIFGYGKI 171 Query: 165 GQAIARRLKPFGVQRFLYTGRQPRPEEA-AEFQAEFVSTPELAAQSDFIVVACSLTPATE 223 GQ +A + FG+ ++ GR+ E A A+ A S L QSD + V L T Sbjct: 172 GQLVAGYGRAFGMNVLVW-GRENSKERARADGFAVAESKDALFEQSDVLSVHLRLNDETR 230 Query: 224 GLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLL 283 + +MK TA+F+N SR ++V ++ + AL G+ A +DV EP+ H LL Sbjct: 231 SIITVADLTRMKPTALFVNTSRAELVEENGMVTALNRGRPGMAAIDVFETEPILQGHTLL 290 Query: 284 TLKNCVILPHIGSATHRTRNTMSLLAANNLLAGLRG 319 ++NC+ PHIG + +A N+L L+G Sbjct: 291 RMENCICTPHIGYVERESYEMYFGIAFQNILDILQG 326 >3EVT-A nrPDB Length = 324 Score = 109 bits (273), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 79/248 (31%), Positives = 119/248 (47%), Gaps = 5/248 (2%) Query: 65 KRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCR 124 K IL LK + +S G+D+L L ++ G+ V T + D +E ++ +L+ R Sbjct: 52 KTILARPTNQLKFVQVISAGVDYLPLKALQAAGVVVANTSGIHADAISESVLAAMLSVVR 111 Query: 125 RLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTG 184 A + G W L + LT + I G G+IGQ++A + G+ + Sbjct: 112 GYHAAW--LNQRGARQWA-LPMTTSTLTGQQLLIYGTGQIGQSLAAKASALGM-HVIGVN 167 Query: 185 RQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINIS 244 P + F +T + A ++FIV A LTP T L + + FQ+ K+ + INI Sbjct: 168 TTGHPADHFHETVAFTATADALATANFIVNALPLTPTTHHLFSTELFQQTKQQPMLINIG 227 Query: 245 RGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHI-GSATHRTRN 303 RG V+ L AL +++ A LDVT PEPLPT+HPL + +I PHI G H Sbjct: 228 RGPAVDTTALMTALDHHQLSMAALDVTEPEPLPTDHPLWQRDDVLITPHISGQIAHFRAT 287 Query: 304 TMSLLAAN 311 + AAN Sbjct: 288 VFPIFAAN 295 >6D4C-A nrPDB Length = 364 Score = 109 bits (273), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 73/246 (29%), Positives = 115/246 (46%), Gaps = 11/246 (4%) Query: 62 HVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTD--TTAELAVSLL 119 ++ K +D A LK++ VG DH+ LD I + G ++ ++ + AE + + Sbjct: 73 YITKERIDKA-KKLKLVVVAGVGSDHIDLDYINQTGKKISVLEVTGSNVVSGAEHVLMTM 131 Query: 120 LTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQR 179 L R A E++ N W + Y + T+ IG GRIG + RL PF + Sbjct: 132 LVLVRNFVPAHEQIINHDWEV-AAIAKDAYDIEGKTIATIGAGRIGYRVLERLVPFNPKE 190 Query: 180 FLYTGRQPRPEEAAEFQA--EFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKET 237 LY Q P++A E + EL AQ+D + + L T+GL NK+ K K+ Sbjct: 191 LLYYDYQALPKDAEEKVGARRVENIEELVAQADIVTINAPLHAGTKGLINKELLSKFKKG 250 Query: 238 AVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKN-----CVILP 292 A +N +RG + +D+ AL SG++ G DV P+P P +HP ++N + P Sbjct: 251 AWLVNTARGAICVAEDVAAALESGQLRGYGGDVWFPQPAPKDHPWRDMRNKYGAGNAMTP 310 Query: 293 HIGSAT 298 H T Sbjct: 311 HYSGTT 316 >3WR5-A nrPDB Length = 406 Score = 108 bits (271), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 74/235 (31%), Positives = 112/235 (47%), Gaps = 12/235 (5%) Query: 70 AAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEA 129 A NLK+ T +G DH+ L RGI V + + AE V ++L R + Sbjct: 115 AKAKNLKLALTAGIGSDHVDLQSAIDRGITVAEVTYCNSISVAEHVVMMILGLVRNYIPS 174 Query: 130 IEEVKNGGWTSWKPLWLC---GYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQ 186 + + GGW + C Y L TVG + GRIG A+ RRL PF V + YT R Sbjct: 175 HDWARKGGWN----IADCVEHSYDLEGMTVGSVAAGRIGLAVLRRLAPFDV-KLHYTDRH 229 Query: 187 PRPEEAAEFQAEFV---STPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINI 243 PE A E + V + ++ D + + L P TE + N + + K A +N Sbjct: 230 RLPE-AVEKELGLVWHDTREDMYPHCDVVTLNVPLHPETEHMINDETLKLFKRGAYIVNT 288 Query: 244 SRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSAT 298 +RG + ++D + +A+ SG++A DV P+P P +HP T+K + PHI + Sbjct: 289 ARGKLADRDAIVRAIESGQLAGYAGDVWFPQPAPKDHPWRTMKWEGMTPHISGTS 343 >5Z1Z-A nrPDB Length = 329 Score = 106 bits (264), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 64/201 (31%), Positives = 106/201 (52%), Gaps = 7/201 (3%) Query: 75 LKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVK 134 +K I+ G +++ LD K+ G++V P + AE A+ +++T RR+ A + + Sbjct: 69 VKYIALRCAGFNNVDLDAAKELGLKVVRVPAYDPEAVAEHAIGMMMTLNRRIHRAYQRTR 128 Query: 135 NGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAA- 193 + ++ L G+ + T G+IG G+IG A+ R LK FG++ + P P AA Sbjct: 129 DANFSLE---GLTGFTMYGKTAGVIGTGKIGVAMLRILKGFGMRLLAF---DPYPSAAAL 182 Query: 194 EFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDD 253 E E+V P L ++SD I + C LTP L N+ F +MK + +N SRG +++ Sbjct: 183 ELGVEYVDLPTLFSESDVISLHCPLTPENYHLLNEAAFDQMKNGVMIVNTSRGALIDSQA 242 Query: 254 LYQALASGKIAAAGLDVTSPE 274 +AL + KI + G+DV E Sbjct: 243 AIEALKNQKIGSLGMDVYENE 263 >4S1V-D nrPDB Length = 332 Score = 105 bits (261), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 78/227 (34%), Positives = 116/227 (51%), Gaps = 11/227 (4%) Query: 74 NLKVISTMSVGIDHLALDEIKKRGIRV--GYTPDVLTDTTAELAVSLLLTTCRRLPEAIE 131 NLK+IS +H+ + ++ G+ V G V AEL SL+L R LP IE Sbjct: 70 NLKLISQTGKVSNHIDVPLCERYGVTVLEGIGSPV---APAELCWSLILAASRHLPSYIE 126 Query: 132 EVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEE 191 ++ G W L L G L+ T+GI GLG+IGQ IA+ FG+ ++ G + ++ Sbjct: 127 QLHAGHWQQNGGLGL-GRTLSGRTLGIWGLGKIGQRIAQFGHVFGMPILVW-GSEASRQK 184 Query: 192 AAE--FQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVV 249 A E +QA E A++D + + L AT G+ K MK ++F+N SR ++V Sbjct: 185 ALELGYQAA-ADKAEFFAKADVLSLHLRLNDATRGIVTKQDLLAMKPDSLFVNTSRAELV 243 Query: 250 NQDDLYQALASGKIAAAGLDVTSPEP-LPTNHPLLTLKNCVILPHIG 295 LY + + + A +DV EP LP N PLL+L N + PH+G Sbjct: 244 ESGALYSVMQANPMRQAAVDVYENEPALPNNEPLLSLPNVLCAPHLG 290 >5MH6-A nrPDB Length = 308 Score = 103 bits (258), Expect = 8e-23, Method: Compositional matrix adjust. Identities = 70/240 (29%), Positives = 112/240 (46%), Gaps = 11/240 (4%) Query: 78 ISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGG 137 + + G D + ++ G + + + T E +LT RRL + + Sbjct: 62 VHCIRAGYDEFPVGVYEEAGTYLTNSTGIHGTTVGETVAGYMLTFARRLHAYRDAQHDHA 121 Query: 138 WTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQA 197 W P + + L V ++GLG +G+ + R G++ + R P + Sbjct: 122 WD--LPRYEEPFTLAGERVCVVGLGTLGRGVVDRAAALGME-VVGVRRSGDPVD----NV 174 Query: 198 EFVSTP----ELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDD 253 V TP E A + F+V+A LT TEG+ F+ M+E A +N++RG VV + D Sbjct: 175 STVYTPDRLHEAIADARFVVLATPLTDETEGMVAAPEFETMREDASLVNVARGPVVVESD 234 Query: 254 LYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTMSLLAANNL 313 L AL SG IA A LDV S EPLP + PL ++ +I PH+ +AT + ++ L N+ Sbjct: 235 LVAALDSGDIAGAALDVFSEEPLPEDSPLWDFEDVLITPHVSAATSKYHEDVAALIRENI 294 >4CUK-A nrPDB Length = 338 Score = 101 bits (252), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 64/201 (31%), Positives = 103/201 (51%), Gaps = 7/201 (3%) Query: 75 LKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVK 134 +K I+ G +++ LD K+ G++V P + AE A+ +++T RR+ A + + Sbjct: 69 VKYIALRCAGFNNVDLDAAKELGLQVVRVPAYSPEAVAEHAIGMMMTLNRRIHRAYQRTR 128 Query: 135 NGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAA- 193 + ++ L G+ + T G+IG G+IG A R LK FG++ + P P AA Sbjct: 129 DANFSLE---GLTGFTMHGKTAGVIGTGKIGVAALRILKGFGMRLLAF---DPYPSTAAL 182 Query: 194 EFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDD 253 + E+V L A+SD I + C LTP L N F +MK + IN SRG +++ Sbjct: 183 DLGVEYVDLQTLFAESDVISLHCPLTPENYHLLNHAAFDQMKNGVMIINTSRGALIDSQA 242 Query: 254 LYQALASGKIAAAGLDVTSPE 274 +AL + KI + G+DV E Sbjct: 243 AIEALKNQKIGSLGMDVYENE 263 >3FN4-A nrPDB Length = 401 Score = 101 bits (252), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 68/234 (29%), Positives = 107/234 (45%), Gaps = 10/234 (4%) Query: 70 AAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEA 129 A LK+ T +G DH+ L I V +++ AE V ++L R + Sbjct: 109 AKAPKLKLALTAGIGSDHVDLQAAIDNNITVAEVTYCNSNSVAEHVVMMVLGLVRNYIPS 168 Query: 130 IEEVKNGGWTSWKPLWLC---GYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQ 186 + +NGGW + C Y + VG + GRIG + R L PF + YT R Sbjct: 169 HDWARNGGWN----IADCVARSYDVEGMHVGTVAAGRIGLRVLRLLAPFDMH-LHYTDRH 223 Query: 187 PRPEEA-AEFQAEFVSTPE-LAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINIS 244 PE E + +T E + D + + C L P TE + N + + K A +N + Sbjct: 224 RLPEAVEKELNLTWHATREDMYGACDVVTLNCPLHPETEHMINDETLKLFKRGAYLVNTA 283 Query: 245 RGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSAT 298 RG + ++D + +AL SG++A DV P+P P +HP T+ + + PHI + Sbjct: 284 RGKLCDRDAIVRALESGRLAGYAGDVWFPQPAPNDHPWRTMPHNGMTPHISGTS 337 >6ABJ-A nrPDB Length = 345 Score = 98.2 bits (243), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 82/280 (29%), Positives = 127/280 (45%), Gaps = 21/280 (7%) Query: 57 CLLSDHVDKRILD--AAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAEL 114 ++D + + +L+ AAG ++++ S G +H+ L + G+ V + P AE Sbjct: 66 AFVNDDLSRPVLERLAAGGT-RLVALRSAGYNHVDLAAAEALGLPVVHVPAYSPHAVAEH 124 Query: 115 AVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKP 174 AV L+LT RRL A + G ++ L G+ L VG+IG G+IG+ AR + Sbjct: 125 AVGLILTLNRRLHRAYNRTREGDFSLHG---LTGFDLHGKRVGVIGTGQIGETFARIMAG 181 Query: 175 FGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKM 234 FG + Y P P A +++ L A+SD + + C LT T L + M Sbjct: 182 FGCELLAYD-PYPNPRIQA-LGGRYLALDALLAESDIVSLHCPLTADTRHLIDAQRLATM 239 Query: 235 KETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVT-----------SPEPLPTN--HP 281 K A+ IN RG +VN L +AL SG++ GLDV S +PL + Sbjct: 240 KPGAMLINTGRGALVNAAALIEALKSGQLGYLGLDVYEEEADIFFEDRSDQPLQDDVLAR 299 Query: 282 LLTLKNCVILPHIGSATHRTRNTMSLLAANNLLAGLRGEP 321 LL+ N V+ H T ++ +N+ A G P Sbjct: 300 LLSFPNVVVTAHQAFLTREALAAIADTTLDNIAAWQDGTP 339 >3HG7-A nrPDB Length = 324 Score = 97.8 bits (242), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 79/283 (27%), Positives = 128/283 (45%), Gaps = 12/283 (4%) Query: 46 ERGVAGAHGLLCLLSDHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPD 105 E+ + AH L+++ + L A L + G+D L LD +R ++ Sbjct: 42 EKLIGEAH---ILMAEPARAKPLLAKANKLSWFQSTYAGVDVL-LDARCRRDYQLTNVRG 97 Query: 106 VLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIG 165 + +E LL+ R+LP E+ K W S P GL T+ I+G G IG Sbjct: 98 IFGPLMSEYVFGHLLSLMRQLPLYREQQKQRLWQS-HPYQ----GLKGRTLLILGTGSIG 152 Query: 166 QAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGL 225 Q IA K FG+ + L R R + + + ++ AQ+D IV T T L Sbjct: 153 QHIAHTGKHFGM-KVLGVSRSGRERAGFDQVYQLPALNKMLAQADVIVSVLPATRETHHL 211 Query: 226 CNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTL 285 F+ K A+ N+ RG+ +N+ DL AL +GK+ A LDV EPLP + PL Sbjct: 212 FTASRFEHCKPGAILFNVGRGNAINEGDLLTALRTGKLGMAVLDVFEQEPLPADSPLWGQ 271 Query: 286 KNCVILPHIGSATHRTRNTMSLLAANNLLAGLRGEPMPSELKL 328 N +I PH ++ + + ++ + N + + G+P+ ++ Sbjct: 272 PNLIITPH--NSAYSFPDDVAQIFVRNYIRFIDGQPLDGKIDF 312 >2PA3-A nrPDB Length = 410 Score = 97.4 bits (241), Expect = 8e-21, Method: Compositional matrix adjust. Identities = 80/276 (28%), Positives = 123/276 (44%), Gaps = 11/276 (3%) Query: 43 KELERGVAGAHGLLCLLSDHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGY 102 ++L+ + AH + H+ + +++AA L I ++G + + LD KRGI V Sbjct: 45 EQLKESIRDAHFIGLRSRTHLTEDVINAA-EKLVAIGAFAIGTNQVDLDAAAKRGIPVFN 103 Query: 103 TPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLG 162 P T + AEL + LL R +PEA + G W L + +GIIG G Sbjct: 104 APFSNTRSVAELVIGELLLLLRGVPEANAKAHRG---VWNKLAAGSFEARGKKLGIIGYG 160 Query: 163 RIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPAT 222 IG + + G+ + Y P A Q + +S +L SD + + P+T Sbjct: 161 HIGTQLGILAESLGMYVYFYDIENKLPLGNAT-QVQHLS--DLLNMSDVVSLHVPENPST 217 Query: 223 EGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPL----PT 278 + + MK ++ IN SRG VV+ L ALAS +A A +DV EP P Sbjct: 218 KNMMGAKEISLMKPGSLLINASRGTVVDIPALADALASKHLAGAAIDVFPTEPATNSDPF 277 Query: 279 NHPLLTLKNCVILPHIGSATHRTRNTMSLLAANNLL 314 PL N ++ PHIG +T + + L A L+ Sbjct: 278 TSPLAEFDNVLLTPHIGGSTQEAQENIGLEVAGKLI 313 >2W2L-A nrPDB Length = 348 Score = 94.7 bits (234), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 75/257 (29%), Positives = 122/257 (47%), Gaps = 8/257 (3%) Query: 73 ANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEE 132 ++LKV + G D L LD + +RG+ + T++LA+ L+L+ R + Sbjct: 79 SSLKVFAAAGAGFDWLDLDALNERGVAFANSRGAGDTATSDLALYLILSVFRLASYSERA 138 Query: 133 VKNGGWTSWKPLWL----CGYGLTQSTVGIIGLGRIGQAIARR-LKPFGVQRFLYTGRQP 187 + G ++ + L + +G +GLG I + IAR+ + G++ Y Sbjct: 139 ARTGDPETFNRVHLEIGKSAHNPRGHVLGAVGLGAIQKEIARKAVHGLGMKLVYYDVAPA 198 Query: 188 RPEEAAEFQAEFV-STPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRG 246 E AE V S ELA +SD + V+ T L ++ FF MK + +N +RG Sbjct: 199 DAETEKALGAERVDSLEELARRSDCVSVSVPYMKLTHHLIDEAFFAAMKPGSRIVNTARG 258 Query: 247 DVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTMS 306 V++QD L AL SGK+ +AGLDV EP + L+ +K+ + HIG T + Sbjct: 259 PVISQDALIAALKSGKLLSAGLDVHEFEP-QVSKELIEMKHVTLTTHIGGVAIETFHEFE 317 Query: 307 LLAANNLLAG-LRGEPM 322 L N+ L+G+P+ Sbjct: 318 RLTMTNIDRFLLQGKPL 334 >1DXY-A nrPDB Length = 333 Score = 91.3 bits (225), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 70/260 (26%), Positives = 115/260 (44%), Gaps = 19/260 (7%) Query: 75 LKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVK 134 +K ++ +VG D++ + +K+ GIR+ P AE A++ L R + + +++ Sbjct: 69 IKFLTIRNVGTDNIDMTAMKQYGIRLSNVPAYSPAAIAEFALTDTLYLLRNMGKVQAQLQ 128 Query: 135 NGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAE 194 G + K G L Q TVG++G G IGQ + K FG + Y P P + Sbjct: 129 AGDYE--KAGTFIGKELGQQTVGVMGTGHIGQVAIKLFKGFGAKVIAY---DPYPMKGDH 183 Query: 195 FQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDL 254 ++VS +L QSD I + + N+ F MK A+ IN +R ++++ + Sbjct: 184 PDFDYVSLEDLFKQSDVIDLHVPGIEQNTHIINEAAFNLMKPGAIVINTARPNLIDTQAM 243 Query: 255 YQALASGKIAAAGLDVTSPEPL-------------PTNHPLLTLKNCVILPHIGSATHRT 301 L SGK+A G+D E P LL + N V+ PHI T Sbjct: 244 LSNLKSGKLAGVGIDTYEYETEDLLNLAKHGSFKDPLWDELLGMPNVVLSPHIAYYTETA 303 Query: 302 RNTMSLLAANNLLAGL-RGE 320 + M + +L+ L +GE Sbjct: 304 VHNMVYFSLQHLVDFLTKGE 323 >1HL3-A nrPDB Length = 358 Score = 91.3 bits (225), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 72/258 (27%), Positives = 112/258 (43%), Gaps = 6/258 (2%) Query: 75 LKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVK 134 L++I + G D++ + GI V P + TA+ + +L RR + ++ Sbjct: 89 LRIIVRIGSGFDNIDIKSAGDLGIAVCNVPAASVEETADSTLCHILNLYRRTTWLHQALR 148 Query: 135 NGGWT-SWKPLWLCGYGLTQ---STVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPE 190 G S + + G + T+GIIGLGR+GQA+A R K FG Y Sbjct: 149 EGTRVQSVEQIREVASGAARIRGETLGIIGLGRVGQAVALRAKAFGFNVLFYDPYLSDGI 208 Query: 191 EAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVN 250 E A + +L SD + + C L L N ++M++ A +N +RG +V+ Sbjct: 209 ERALGLQRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVD 268 Query: 251 QDDLYQALASGKIAAAGLDVTSPEPLPTNH-PLLTLKNCVILPHIGSATHRTRNTMSLLA 309 + L QAL G+I A LDV EP + PL N + PH + + M A Sbjct: 269 EKALAQALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQASIEMREEA 328 Query: 310 ANNLLAGLRGEPMPSELK 327 A + + G +P LK Sbjct: 329 AREIRRAITGR-IPDSLK 345 >4HY3-A nrPDB Length = 365 Score = 90.1 bits (222), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 72/252 (28%), Positives = 116/252 (46%), Gaps = 14/252 (5%) Query: 76 KVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKN 135 +++ S ++++ + + +RGI V T V + AE+ + L R + +A + Sbjct: 99 SILNVESNLLNNMPYEVLFQRGIHVVTTGQVFAEPVAEIGLGFALALARGIVDADIAFQE 158 Query: 136 GGWTSWKPLWLCGYG------LTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRP 189 G LW G G + S +GI+G G +G+A+ R L F + ++ PR Sbjct: 159 G-----TELW-GGEGNASARLIAGSEIGIVGFGDLGKALRRVLSGFRARIRVFDPWLPR- 211 Query: 190 EEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVV 249 E E S ++ +SDFI V ++T + + F M+ A FI +SR DVV Sbjct: 212 SMLEENGVEPASLEDVLTKSDFIFVVAAVTSENKRFLGAEAFSSMRRGAAFILLSRADVV 271 Query: 250 NQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTMSLLA 309 + D L A++SG I AA DV EPLP +HP+ +LK + H A M + Sbjct: 272 DFDALMAAVSSGHIVAAS-DVYPEEPLPLDHPVRSLKGFIRSAHRAGALDSAFKKMGDMV 330 Query: 310 ANNLLAGLRGEP 321 ++ RG P Sbjct: 331 LEDMDLMDRGLP 342 >4XA8-A nrPDB Length = 320 Score = 89.4 bits (220), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 70/224 (31%), Positives = 104/224 (46%), Gaps = 8/224 (3%) Query: 74 NLKVISTMSVGIDHL-ALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEE 132 NLK++ + G+D L A D++ + P+ ++ A + +L R +P Sbjct: 70 NLKLVINLGAGVDALVARDDLPDVPVTRLSDPN-MSQMMASFVLFCVLRHARDIPTFERA 128 Query: 133 VKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEA 192 + G W P + VG++GLG +G A A L G ++ R P+ E Sbjct: 129 QREGRWHYVHP-----RTAAEIRVGVLGLGDLGAAAALELARHGFDVRGWS-RTPKALEG 182 Query: 193 AEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQD 252 + P A S+ +VV LTP T GL N + + A FIN++RG VV++ Sbjct: 183 VSCFHGLEALPGFLAGSEIVVVMLPLTPETRGLMNAERLAHLPRGAKFINVARGPVVDEA 242 Query: 253 DLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGS 296 L AL SG IA A LDV EPLP PL + N ++ PH+ S Sbjct: 243 ALIAALRSGHIAEATLDVFEVEPLPVGSPLWAMDNVLVTPHLAS 286 >2OME-A nrPDB Length = 336 Score = 88.6 bits (218), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 70/258 (27%), Positives = 112/258 (43%), Gaps = 6/258 (2%) Query: 75 LKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVK 134 L+VI + G D++ + + GI V P + TA+ + +L RR + ++ Sbjct: 70 LRVIVRIGSGYDNVDIKAAGELGIAVCNIPSAAVEETADSTICHILNLYRRNTWLYQALR 129 Query: 135 NGGWT-SWKPLWLCGYGLTQ---STVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPE 190 G S + + G + T+G+IG GR GQA+A R K FG Y Sbjct: 130 EGTRVQSVEQIREVASGAARIRGETLGLIGFGRTGQAVAVRAKAFGFSVIFYDPYLQDGI 189 Query: 191 EAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVN 250 E + + +L QSD + + C+L L N ++M++ A +N +RG +V+ Sbjct: 190 ERSLGVQRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVD 249 Query: 251 QDDLYQALASGKIAAAGLDVTSPEPLP-TNHPLLTLKNCVILPHIGSATHRTRNTMSLLA 309 + L QAL G+I A LDV EP PL N + PH + + M A Sbjct: 250 EKALAQALKEGRIRGAALDVHESEPFSFAQGPLKDAPNLICTPHTAWYSEQASLEMREAA 309 Query: 310 ANNLLAGLRGEPMPSELK 327 A + + G +P L+ Sbjct: 310 ATEIRRAITGR-IPESLR 326 >4PRK-A nrPDB Length = 336 Score = 87.8 bits (216), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 86/324 (26%), Positives = 147/324 (45%), Gaps = 28/324 (8%) Query: 16 PAEGRVALARAAD----CEVEQWDSDEPIPAKELERGVAGAHGLLCLLSDHVDKRIL--D 69 P+E L A + CE++ D E + A+ +++ VA G+L ++D I+ Sbjct: 8 PSESERKLVAATEKKFGCELKLID--ESLSAENVDQ-VADCDGVLLKPLGNLDDEIVYKK 64 Query: 70 AAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEA 129 A +K I VG + + D KK + V P AE+AV+ + R++ E Sbjct: 65 LADYGIKSIGLRIVGTNTIDFDLAKKYHLTVTNVPVYSPRAIAEMAVTQAMYLNRKIGEF 124 Query: 130 IEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLY-TGRQPR 188 + G +T+ P L + T+G+IG+G IG A+A+ G + Y P Sbjct: 125 KANMDKGDFTN--PDSLISNEIYNKTIGLIGVGHIGSAVAQIFSAMGAKVLAYDVIYNPE 182 Query: 189 PEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDV 248 E + A+F + + ++D I + L +TE + K F +MK A+ IN +RG++ Sbjct: 183 VEPYLTY-ADFDT---VLKEADIISLHTPLLKSTENMIGKKQFAEMKNDAILINAARGEL 238 Query: 249 VNQDDLYQALASGKIAAAGLDVTSPEP-----------LPTNH-PLLTLKNCVILPHIGS 296 V+ L +AL +IAAAGLD + E +P ++ L + N ++ PH Sbjct: 239 VDTAALIEALEKHEIAAAGLDTLAHESSYFFKKVDDAQIPADYKKLAAMPNVIVTPHSAY 298 Query: 297 ATHRTRNTMSLLAANNLLAGLRGE 320 T + M ++ + +A GE Sbjct: 299 FTKTSVRNMIEISLRDTIALANGE 322 >1J49-A nrPDB Length = 333 Score = 84.7 bits (208), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 76/298 (25%), Positives = 133/298 (44%), Gaps = 31/298 (10%) Query: 51 GAHGLLCLLS-DHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVG----YTPD 105 GA G++ D++ + + A + +S +VG+D++ + + K+ G ++ Y+P+ Sbjct: 46 GADGVVVYQQLDYIAETLQALADNGITKMSLRNVGVDNIDMAKAKELGFQITNVPVYSPN 105 Query: 106 VLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIG 165 + + A A +L R +A++E W P G + VG++G G IG Sbjct: 106 AIAEHAAIQAARIL-----RQDKAMDEKVARHDLRWAPT--IGREVRDQVVGVVGTGHIG 158 Query: 166 QAIARRLKPFGVQRFLY-TGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEG 224 Q + ++ FG + Y R P E+ + S +L Q+D I + PA Sbjct: 159 QVFMQIMEGFGAKVITYDIFRNPELEKKGYYVD---SLDDLYKQADVISLHVPDVPANVH 215 Query: 225 LCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNH---- 280 + N + KMK+ V +N+SRG +V+ D + + L SGKI +DV E N Sbjct: 216 MINDESIAKMKQDVVIVNVSRGPLVDTDAVIRGLDSGKIFGYAMDVYEGEVGIFNEDWEG 275 Query: 281 ---------PLLTLKNCVILPHIG-SATHRTRNTMSLLAANNLLAGLRGEPMPSELKL 328 L+ N ++ PH TH RN M + A +N L + G+ + +K+ Sbjct: 276 KEFPDARLADLIARPNVLVTPHTAFYTTHAVRN-MVVKAFDNNLELVEGKEAETPVKV 332 >3K5P-A nrPDB Length = 416 Score = 83.6 bits (205), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 67/238 (28%), Positives = 106/238 (44%), Gaps = 20/238 (8%) Query: 70 AAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRL-PE 128 AA L + SVG + + L +KRGI V P T + AEL + ++ RR+ P Sbjct: 76 AAANRLIAVGCFSVGTNQVELKAARKRGIPVFNAPFSNTRSVAELVIGEIIMLMRRIFPR 135 Query: 129 AIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPR 188 ++ G W+ + + T+GI+G G IG + + G+ Y Sbjct: 136 SVSAHAGG----WEKTAIGSREVRGKTLGIVGYGNIGSQVGNLAESLGMTVRYY------ 185 Query: 189 PEEAAEFQAEFV----STPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINIS 244 + + + Q V S EL SD + + + +T L + +KMK+ A IN + Sbjct: 186 -DTSDKLQYGNVKPAASLDELLKTSDVVSLHVPSSKSTSKLITEAKLRKMKKGAFLINNA 244 Query: 245 RGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNH----PLLTLKNCVILPHIGSAT 298 RG V+ + L + L G +A A +DV EP PL L+N ++ PHIG +T Sbjct: 245 RGSDVDLEALAKVLQEGHLAGAAIDVFPVEPASNGERFSTPLQGLENVILTPHIGGST 302 >2DLD-A nrPDB Length = 337 Score = 83.2 bits (204), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 77/298 (25%), Positives = 130/298 (43%), Gaps = 31/298 (10%) Query: 51 GAHGLLCLLS-DHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVG----YTPD 105 GA G++ D+ + A A + +S +VG+D++ +D+ K+ G ++ Y+P+ Sbjct: 46 GADGVVVYQQLDYTADTLQALADAGVTKMSLRNVGVDNIDMDKAKELGFQITNVPVYSPN 105 Query: 106 VLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIG 165 + + A + + +L +R+ E + + W P G + VG++G G IG Sbjct: 106 AIAEHAA-IQAARVLRQDKRMDEKMAKRD----LRWAPT--IGREVRDQVVGVVGTGHIG 158 Query: 166 QAIARRLKPFGVQRFLYT-GRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEG 224 Q R ++ FG + Y + P E+ + S +L Q+D I + PA Sbjct: 159 QVFMRIMEGFGAKVIAYDIFKNPELEKKGYYVD---SLDDLYKQADVISLHVPDVPANVH 215 Query: 225 LCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPE---------- 274 + N +MK+ V +N SRG +V+ D + + L SGKI +D E Sbjct: 216 MINDKSIAEMKDGVVIVNCSRGRLVDTDAVIRGLDSGKIFGFVMDTYEDEVGVFNKDWEG 275 Query: 275 ---PLPTNHPLLTLKNCVILPHIG-SATHRTRNTMSLLAANNLLAGLRGEPMPSELKL 328 P L+ N ++ PH TH RN M + A NN L + GE S + L Sbjct: 276 KEFPDKRLADLIDRPNVLVTPHTAFYTTHAVRN-MVVKAFNNNLKLINGEKPDSPVAL 332 >5TSD-A nrPDB Length = 322 Score = 81.6 bits (200), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 72/263 (27%), Positives = 106/263 (40%), Gaps = 32/263 (12%) Query: 74 NLKVISTMSVGIDHLALDEIKKRGIRVGYTPDV---------LTDTTAELAVSLLLTTCR 124 NLKVI + G+DH+ I + PD+ LT +E V L R Sbjct: 68 NLKVIFSGGAGVDHI---------IGMAGLPDIPIVRFVDRSLTTRMSEWVVMQCLMHLR 118 Query: 125 RLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTG 184 + W L + TVG++GLG +GQ +LK G ++ Sbjct: 119 GQYGHDSHQRRREWAK-----LIAPEAAEVTVGVMGLGILGQDAVAKLKVMGFNVIGWSR 173 Query: 185 RQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETA-----V 239 + E F A A++D +V LTP T G + + F+K++ V Sbjct: 174 TRKTIEGVETFDAG--ELDRFLAKTDILVGLLPLTPETTGFYDSELFKKLRRDGALGQPV 231 Query: 240 FINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATH 299 FIN RG + D+ A+ G + A LDV EPL T+ PL L+N I PH + + Sbjct: 232 FINAGRGKSQIETDIVSAVREGTLGGASLDVFEVEPLATDSPLWELENVFITPHDAAVSE 291 Query: 300 RTRNTMSLLAANNLLAGLRGEPM 322 N + + RGEP+ Sbjct: 292 --ENALFRHVEMQIARFERGEPL 312 >2YQ5-A nrPDB Length = 343 Score = 81.3 bits (199), Expect = 6e-16, Method: Compositional matrix adjust. Identities = 71/264 (26%), Positives = 113/264 (42%), Gaps = 24/264 (9%) Query: 75 LKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVK 134 +K I VG + + D KK + V P AE+ V+ + R++ E + Sbjct: 71 VKCIGLRIVGFNTINFDWTKKYNLLVTNVPVYSPRAIAEMTVTQAMYLLRKIGEFRYRMD 130 Query: 135 NGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLY-TGRQPRPEEAA 193 + +W P L + TVG+IG+G IG A+A G + Y P Sbjct: 131 HDHDFTW-PSNLISNEIYNLTVGLIGVGHIGSAVAEIFSAMGAKVIAYDVAYNP------ 183 Query: 194 EFQAEFVSTP--ELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQ 251 EF+ T + ++D + + L P+TE + + ++MK++A IN +RG++V+ Sbjct: 184 EFEPFLTYTDFDTVLKEADIVSLHTPLFPSTENMIGEKQLKEMKKSAYLINCARGELVDT 243 Query: 252 DDLYQALASGKIAAAGLDVTSPEPLPTNHPLLT-------------LKNCVILPHIGSAT 298 L +AL G+IA AGLD + E H LT + N VI PH T Sbjct: 244 GALIKALQDGEIAGAGLDTLAGESSYFGHTGLTDSEIPEDYKTLAKMPNVVITPHSAFYT 303 Query: 299 HRT-RNTMSLLAANNLLAGLRGEP 321 + RN + + + L G P Sbjct: 304 ETSIRNMVQICLTDQLTIAKGGRP 327 >1XDW-A nrPDB Length = 331 Score = 80.9 bits (198), Expect = 7e-16, Method: Compositional matrix adjust. Identities = 64/253 (25%), Positives = 105/253 (41%), Gaps = 19/253 (7%) Query: 75 LKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVK 134 +K I T + G DH+ + K+ G + + P + AELAV+ + R Sbjct: 70 VKYILTRTAGTDHIDKEYAKELGFPMAFVPRYSPNAIAELAVTQAMMLLRHTAYTTSRTA 129 Query: 135 NGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAE 194 + ++ + TVG++GLGRIG+ A+ G G + E Sbjct: 130 KKNFKV--DAFMFSKEVRNCTVGVVGLGRIGRVAAQIFHGMGAT---VIGEDVFEIKGIE 184 Query: 195 FQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDL 254 VS E+ +SD I + + +DF +KMK+ A+ +N +RG +V+ + + Sbjct: 185 DYCTQVSLDEVLEKSDIITIHAPYIKENGAVVTRDFLKKMKDGAILVNCARGQLVDTEAV 244 Query: 255 YQALASGKIAAAGLDVTSPEPL-------------PTNHPLLTLK-NCVILPHIGSATHR 300 +A+ SGK+ G DV E P L+ L +I PH+GS T Sbjct: 245 IEAVESGKLGGYGCDVLDGEASVFGKDLEGQKLENPLFEKLVDLYPRVLITPHLGSYTDE 304 Query: 301 TRNTMSLLAANNL 313 M ++ NL Sbjct: 305 AVKNMVEVSYQNL 317 >3KBO-A nrPDB Length = 315 Score = 80.5 bits (197), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 71/237 (29%), Positives = 108/237 (45%), Gaps = 18/237 (7%) Query: 71 AGANLKVISTMSVGIDHL-----ALDEIKKRGIRVGYTPDV-LTDTTAELAVSLLLTTCR 124 AG LK + + G+D + A E+ I + D + E AVS +L R Sbjct: 56 AGRRLKAVFVLGAGVDAILSKLNAHPEMLDASIPLFRLEDTGMGLQMQEYAVSQVLHWFR 115 Query: 125 RLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTG 184 R + + +KN WKPL Y + +VGI+G G +G +A L+ +G ++ Sbjct: 116 RF-DDYQALKNQA--LWKPL--PEYTREEFSVGIMGAGVLGAKVAESLQAWGFPLRCWS- 169 Query: 185 RQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATE---GLCNKDFFQKMKETAVFI 241 R ++ +V EL A + V +L P T G+ N + ++ + A + Sbjct: 170 ---RSRKSWPGVESYVGREELRAFLNQTRVLINLLPNTAQTVGIINSELLDQLPDGAYVL 226 Query: 242 NISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSAT 298 N++RG V + DL AL SGK+ A LDV S EPLP PL + PHI + T Sbjct: 227 NLARGVHVQEADLLAALDSGKLKGAMLDVFSQEPLPQESPLWRHPRVAMTPHIAAVT 283 >4XKJ-A nrPDB Length = 335 Score = 77.8 bits (190), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 81/259 (31%), Positives = 123/259 (47%), Gaps = 23/259 (8%) Query: 75 LKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVK 134 L+ +++ + G D + L++ +RG+ V P ++ AELA++ + R LP + + + Sbjct: 70 LRQLTSRTAGYDMIDLEQASERGLVVTNVPAYSPNSVAELALTQTMRLIRNLP--LFDAR 127 Query: 135 NGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAE 194 G ++ L + TVGIIG GRIG +AR K G T E E Sbjct: 128 -GAEQDFRWAGLMAREIRSLTVGIIGAGRIGGTVARLFKALGA-----TVIANDIVERVE 181 Query: 195 FQ--AEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQD 252 + +VS EL +D + + L +T L + D MK AV IN SRG VV+ D Sbjct: 182 LKDIVTYVSKEELLQAADVVTLHVPLMDSTTQLIDADALALMKNDAVLINASRGPVVDTD 241 Query: 253 DLYQALASGKIAAAGLDVTSPE-----------PLPTNH--PLLTLKNCVILPHIGSATH 299 L AL + +IA A LD + E LP+ L TL N +I PHIG T+ Sbjct: 242 ALIAALQNKQIAGAALDTLNGEEHFFNQDLCGKELPSEQLKVLRTLPNVLITPHIGFYTN 301 Query: 300 RTRNTMSLLAANNLLAGLR 318 + M ++ N++LA L+ Sbjct: 302 KAVQNMVEISLNDVLAILK 320 >4N18-A nrPDB Length = 332 Score = 76.6 bits (187), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 61/224 (27%), Positives = 93/224 (41%), Gaps = 6/224 (2%) Query: 75 LKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVK 134 LK+I S G+DHL + E A+ +L R A+ + Sbjct: 83 LKLIQAASAGVDHLPPALFASEIPLCRVIDEDFRHGMFEYALWSVLWFQRHFDRALAHQR 142 Query: 135 NGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAE 194 W + + +GI+GLG IG IA +L G + ++ + + Sbjct: 143 TQTWKLYPQRAAADF-----HIGIMGLGEIGGYIADQLARLGYRVSGWSRSEKQLAGVTC 197 Query: 195 FQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDL 254 ++ E + D ++ LT T G+ F ++ AV IN RG+ + DD+ Sbjct: 198 YRGE-EALDHFLGSLDGLINLLPLTAQTRGILAAPLFNRLPAGAVLINCGRGEHMVNDDV 256 Query: 255 YQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSAT 298 AL SG++A A LDV EPLP + PL VI PH+ SA Sbjct: 257 LAALESGQLAGAVLDVFPQEPLPADDPLWRHPQVVITPHMASAA 300 >4WEQ-A nrPDB Length = 341 Score = 72.8 bits (177), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 47/149 (31%), Positives = 70/149 (46%), Gaps = 7/149 (4%) Query: 155 TVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVV 214 TVGI+G+G +GQ AR+L G + ++ R R E E + ++DF+V Sbjct: 163 TVGIMGMGVLGQDAARKLAAMGFKVIGWS-RSKRVIEGVE-TYDAAGLDAFLGRTDFLVG 220 Query: 215 ACSLTPATEGLCNKDFFQKMKETA-----VFINISRGDVVNQDDLYQALASGKIAAAGLD 269 LTP T G+ N F K+ VFIN RG + D+ + L SG + A LD Sbjct: 221 LLPLTPDTRGIFNAALFAKLSRNGPFGAPVFINAGRGGSQVEADILECLDSGVLGGASLD 280 Query: 270 VTSPEPLPTNHPLLTLKNCVILPHIGSAT 298 V EPL + N + PH+ +++ Sbjct: 281 VFEREPLSPESRFWDMPNVYVTPHVAASS 309 >5C5I-A nrPDB Length = 316 Score = 70.5 bits (171), Expect = 9e-13, Method: Compositional matrix adjust. Identities = 65/227 (28%), Positives = 103/227 (45%), Gaps = 10/227 (4%) Query: 74 NLKVISTMSVGIDHLA--LDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIE 131 NL I ++ G++ L L + + +R+ P+ L T AE A++ R +P Sbjct: 66 NLVWIHSLWAGVERLVAELGHLARPIVRL-VDPE-LARTMAEAALAWTYYLFRDMPAYAA 123 Query: 132 EVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEE 191 + + W L ++TVG++GLG +G A A RL+ G ++ R P+ Sbjct: 124 QQRARVWKG-----LPYKRPERTTVGVLGLGELGAAAALRLRDAGFDVHGWS-RSPKEIA 177 Query: 192 AAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQ 251 A + + Q + +V LT T GL + + E A +N +RG +++ Sbjct: 178 GVTCHAGEETLERMLGQVEILVCLLPLTGETRGLLDARRLACLPEGAQIVNFARGPILDS 237 Query: 252 DDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSAT 298 L +AL SG+I A LDV EPLP P +LPHI +AT Sbjct: 238 AALIEALDSGRIGHAVLDVFEVEPLPEASPFWGHPKVTVLPHISAAT 284 >3OET-A nrPDB Length = 381 Score = 64.3 bits (155), Expect = 7e-11, Method: Compositional matrix adjust. Identities = 66/273 (24%), Positives = 108/273 (39%), Gaps = 39/273 (14%) Query: 7 MKVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLSDHVDKR 66 MK+ V +P R +R + + PIP +EL A L+ V++ Sbjct: 4 MKILVDENMPY-ARELFSRLGEVKAV---PGRPIPVEELNH----ADALMVRSVTKVNES 55 Query: 67 ILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRL 126 +L +G + + T + G DH+ +K+ GI P E S LL R Sbjct: 56 LL--SGTPINFVGTATAGTDHVDEAWLKQAGIGFSAAPGCNAIAVVEYVFSALLMLAER- 112 Query: 127 PEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQ 186 G+ L T+GI+G+G +G + RL+ G++ L Sbjct: 113 --------------------DGFSLRDRTIGIVGVGNVGSRLQTRLEALGIRTLLCDP-- 150 Query: 187 PRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTP----ATEGLCNKDFFQKMKETAVFIN 242 P A + +F + EL ++D + L T L ++ +++K A+ IN Sbjct: 151 --PRAARGDEGDFRTLDELVQEADVLTFHTPLYKDGPYKTLHLADETLIRRLKPGAILIN 208 Query: 243 ISRGDVVNQDDLYQALASGKIAAAGLDVTSPEP 275 RG VV+ L L +G+ + LDV EP Sbjct: 209 ACRGPVVDNAALLARLNAGQPLSVVLDVWEGEP 241 >5DT9-A nrPDB Length = 387 Score = 63.2 bits (152), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 54/210 (25%), Positives = 87/210 (41%), Gaps = 29/210 (13%) Query: 70 AAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEA 129 A LK + T + G+DH+ +++RGI P AE S+L+ ++ Sbjct: 61 AKANRLKFVGTATAGMDHVDQALLRERGIFFTAAPGCNKVGVAEYVFSVLMVLAQQQ--- 117 Query: 130 IEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRP 189 G+ + TVGIIG G++G +A+ L G++ L P Sbjct: 118 ------------------GFSVFDKTVGIIGAGQVGSYLAKCLSGIGMKVLL----NDPP 155 Query: 190 EEAAEFQAEFVSTPELAAQSDFIVVACSLTPA----TEGLCNKDFFQKMKETAVFINISR 245 ++A + EF L Q+D I + +T T L + ++++ + IN +R Sbjct: 156 KQAQGDEREFTELETLLKQADVITLHTPITRGGEWPTHHLIDAAILEQLRSDQILINAAR 215 Query: 246 GDVVNQDDLYQALASGKIAAAGLDVTSPEP 275 G VV+ L L G A LDV EP Sbjct: 216 GPVVDNAALKARLQQGDGFTAVLDVFEFEP 245 >3GVX-A nrPDB Length = 290 Score = 62.8 bits (151), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 69/258 (26%), Positives = 117/258 (45%), Gaps = 17/258 (6%) Query: 64 DKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTC 123 D+ +L G K+I +S G+DH+ ++ I + + + + + AE A +LLL Sbjct: 42 DRYVL---GKRTKMIQAISAGVDHIDVNGIPE-NVVLCSNAGAYSISVAEHAFALLLAHA 97 Query: 124 RRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYT 183 + + E E +K G + P L YG +G G+GR +A K FG++ YT Sbjct: 98 KNILENNELMKAGIFRQ-SPTTLL-YGKALGILGYGGIGR---RVAHLAKAFGMRVIAYT 152 Query: 184 GRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINI 243 + ++ + +E S +L QSDF+++A LT T G+ N ++ +N+ Sbjct: 153 --RSSVDQNVDVISE--SPADLFRQSDFVLIAIPLTDKTRGMVNSRLLANARKNLTIVNV 208 Query: 244 SRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHI-GSATHRTR 302 +R DVV++ D+ L DV EP T L+N ++ PH+ G + Sbjct: 209 ARADVVSKPDMIGFLKERSDVWYLSDVWWNEPEITE---TNLRNAILSPHVAGGMSGEIM 265 Query: 303 NTMSLLAANNLLAGLRGE 320 + LA N+ GE Sbjct: 266 DIAIQLAFENVRNFFEGE 283 >1QP8-A nrPDB Length = 303 Score = 56.2 bits (134), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 64/244 (26%), Positives = 103/244 (42%), Gaps = 15/244 (6%) Query: 75 LKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVK 134 LK I ++ G+DHL + I + V D AE A++LLL +R+ + E++K Sbjct: 51 LKFIQVVTAGLDHLPWESIPPH-VTVAGNAGSNADAVAEFALALLLAPYKRIIQYGEKMK 109 Query: 135 NGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAE 194 G + + L + V ++GLG IG + + L G Q ++ R P+ E Sbjct: 110 RGDYGRDVEIPL----IQGEKVAVLGLGEIGTRVGKILAALGAQVRGFS-RTPK-----E 159 Query: 195 FQAEFVSTPELA-AQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDD 253 F ++ E A ++ V A L T GL M E AVF+N+ R +V+++D Sbjct: 160 GPWRFTNSLEEALREARAAVCALPLNKHTRGLVKYQHLALMAEDAVFVNVGRAEVLDRDG 219 Query: 254 LYQALASGKIAAAGLDV-TSPEPLPTNHPLLTLKNCVILPHI--GSATHRTRNTMSLLAA 310 + + L DV + +L N V P + G R M + A Sbjct: 220 VLRILKERPQFIFASDVWWGRNDFAKDAEFFSLPNVVATPWVAGGYGNERVWRQMVMEAV 279 Query: 311 NNLL 314 NL+ Sbjct: 280 RNLI 283 >4NFY-A nrPDB Length = 307 Score = 48.9 bits (115), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 50/228 (21%), Positives = 102/228 (44%), Gaps = 30/228 (13%) Query: 31 VEQWDSDEPIPAKELERGVAGAHGLLCLLSDHVDKRILDAAGANLKVISTMSVGIDHLAL 90 +E++ E + +ER + A G++ + SD +D+ I+ AG +K+I G D++ + Sbjct: 33 IEKYKKKEDV----IER-IKDADGVI-VRSDKIDEEII-KAGEKVKIIVRAGAGYDNIDI 85 Query: 91 DEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYG 150 + + I V TP + AEL + +++ R+ G+ K G Sbjct: 86 EACNQGKIVVMNTPGQNRNGVAELCIGMMIFGFRK-----------GFKEGK-----GRE 129 Query: 151 LTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSD 210 L T+GI G G +G+ + + G++ +Y P E Q + + EL + Sbjct: 130 LKDKTLGICGCGYVGKRVKEIAEGIGMKIKVYD-----PFITTENQVKKIE--ELFEECQ 182 Query: 211 FIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQAL 258 I + LT T+G + +K+ + N +R ++++++ L + + Sbjct: 183 VISLHLPLTKETKGKIGYELIKKLPYGGMICNTARKEIIDEEGLIRIM 230 >2O4C-A nrPDB Length = 380 Score = 48.5 bits (114), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 63/246 (25%), Positives = 98/246 (39%), Gaps = 33/246 (13%) Query: 71 AGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAI 130 AG+ ++ + T ++G DHL LD + GI P + + LL A+ Sbjct: 55 AGSPVRFVGTCTIGTDHLDLDYFAEAGIAWSSAPGCNARGVVDYVLGCLL--------AM 106 Query: 131 EEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPE 190 EV+ G L + T G++G G++G + L+ G + + P Sbjct: 107 AEVR-------------GADLAERTYGVVGAGQVGGRLVEVLRGLGWKVLVCDP----PR 149 Query: 191 EAAEFQAEFVSTPELAAQSDFIVVACSLT----PATEGLCNKDFFQKMKETAVFINISRG 246 +A E EFVS L A++D I + L T L ++ ++ +N SRG Sbjct: 150 QAREPDGEFVSLERLLAEADVISLHTPLNRDGEHPTRHLLDEPRLAALRPGTWLVNASRG 209 Query: 247 DVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIG--SATHRTRNT 304 VV+ L + L G LDV E P P L + + PHI S + R T Sbjct: 210 AVVDNQALRRLLEGGADLEVALDVWEGE--PQADPELAARCLIATPHIAGYSLEGKLRGT 267 Query: 305 MSLLAA 310 + A Sbjct: 268 AQIYQA 273 >3AK5-A nrPDB Length = 975 Score = 33.9 bits (76), Expect = 0.11, Method: Compositional matrix adjust. Identities = 20/56 (35%), Positives = 27/56 (48%), Gaps = 2/56 (3%) Query: 196 QAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQ 251 Q EFV T + AA DF V + AT L N + +K + N+S GD N+ Sbjct: 35 QGEFVGTLDKAAMPDFSAVDSEIGVAT--LINPQYIASVKHNGGYTNVSFGDGENR 88 >3NJ4-A nrPDB Length = 435 Score = 33.1 bits (74), Expect = 0.19, Method: Compositional matrix adjust. Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 4/91 (4%) Query: 158 IIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACS 217 + G G +G+ A+ L+ FG R + T P A + V+T + A Q I V Sbjct: 221 VAGYGDVGKGCAQALRGFGA-RVIITEIDPINALQAAMEGYEVTTMDEACQEGNIFVT-- 277 Query: 218 LTPATEGLCNKDFFQKMKETAVFINISRGDV 248 T + F++MK+ A+ NI DV Sbjct: 278 -TTGCIDIILGRHFEQMKDDAIVCNIGHFDV 307 >5U5G-A nrPDB Length = 295 Score = 32.3 bits (72), Expect = 0.31, Method: Compositional matrix adjust. Identities = 14/18 (77%), Positives = 15/18 (83%) Query: 155 TVGIIGLGRIGQAIARRL 172 VG IGLGR+GQAI RRL Sbjct: 4 VVGFIGLGRMGQAICRRL 21 >5H82-A nrPDB Length = 389 Score = 31.6 bits (70), Expect = 0.48, Method: Compositional matrix adjust. Identities = 16/59 (27%), Positives = 28/59 (47%) Query: 136 GGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAE 194 GG + P+ G ++G++G GRIG+ + K FG + + + +EA E Sbjct: 196 GGIVPYSPMRHFGLDKPGLSIGVVGFGRIGKLAVKFAKAFGANVTVISTSISKKQEAIE 254 >3G1U-A nrPDB Length = 437 Score = 30.4 bits (67), Expect = 1.2, Method: Compositional matrix adjust. Identities = 24/93 (25%), Positives = 36/93 (38%), Gaps = 4/93 (4%) Query: 155 TVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVV 214 T + G G +G+ A L+ FG R + T P A + V+ E I V Sbjct: 214 TCCVCGYGDVGKGCAAALRAFGA-RVVVTEVDPINALQASMEGYQVALVEDVMADAHIFV 272 Query: 215 ACSLTPATEGLCNKDFFQKMKETAVFINISRGD 247 T + + D F M++ A+ NI D Sbjct: 273 T---TTGNDDIITSDHFPHMRDDAIVCNIGHFD 302 >6HBE-A nrPDB Length = 451 Score = 29.6 bits (65), Expect = 1.8, Method: Compositional matrix adjust. Identities = 19/61 (31%), Positives = 29/61 (47%), Gaps = 5/61 (8%) Query: 220 PATEGLCNKDFFQKMKETAVFINISRGDVVNQD--DLYQALASGKIAAAGLDVTSPEPLP 277 P T + F+ K+ E V + + VN+D DL + +G+ A +DV PEP Sbjct: 348 PVTVQMVGNSFYPKVLEIPVGTTV---EFVNEDVFDLLEGERTGRHDAVVIDVQGPEPFV 404 Query: 278 T 278 T Sbjct: 405 T 405 >3PEF-A nrPDB Length = 287 Score = 29.6 bits (65), Expect = 1.9, Method: Compositional matrix adjust. Identities = 17/47 (36%), Positives = 24/47 (51%) Query: 157 GIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTP 203 G IGLG +G A+A+ L G ++ + EE A AE +TP Sbjct: 5 GFIGLGIMGSAMAKNLVKAGCSVTIWNRSPEKAEELAALGAERAATP 51 >4OQZ-A nrPDB Length = 289 Score = 29.3 bits (64), Expect = 2.1, Method: Compositional matrix adjust. Identities = 20/64 (31%), Positives = 34/64 (53%), Gaps = 1/64 (1%) Query: 151 LTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSD 210 ++QS V +IGLG +GQA+A G + L+ R + A+ +TPE A ++ Sbjct: 1 MSQS-VTVIGLGPMGQAMAAAYLDRGYEVTLWNRTASRADALVARGAKLAATPEQALSAN 59 Query: 211 FIVV 214 +V+ Sbjct: 60 ELVI 63 >1QB4-A nrPDB Length = 883 Score = 29.3 bits (64), Expect = 2.6, Method: Compositional matrix adjust. Identities = 15/37 (40%), Positives = 21/37 (56%), Gaps = 1/37 (2%) Query: 141 WKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGV 177 W+PL+ C L +GII G + + RR+K FGV Sbjct: 353 WEPLYACYQSLQACGMGIIANGDLLDTL-RRVKCFGV 388 >1GPJ-A nrPDB Length = 404 Score = 28.9 bits (63), Expect = 2.9, Method: Compositional matrix adjust. Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 5/72 (6%) Query: 151 LTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGR--QPRPEEAAEFQAEFVSTPELA-- 206 L TV ++G G +G+ +A+ L GV+ L R + E A + E V EL Sbjct: 165 LHDKTVLVVGAGEMGKTVAKSLVDRGVRAVLVANRTYERAVELARDLGGEAVRFDELVDH 224 Query: 207 -AQSDFIVVACS 217 A+SD +V A + Sbjct: 225 LARSDVVVSATA 236 >5EK8-A nrPDB Length = 668 Score = 28.9 bits (63), Expect = 3.0, Method: Compositional matrix adjust. Identities = 16/53 (30%), Positives = 23/53 (43%) Query: 28 DCEVEQWDSDEPIPAKELERGVAGAHGLLCLLSDHVDKRILDAAGANLKVIST 80 + E+E WD D P+ L +GV +G + D DA L+VI Sbjct: 70 NIELEVWDRDVGTPSDYLGKGVTDQNGRFEIYYDPEKAGFKDAPDLELRVIDN 122 >2L9N-A nrPDB Length = 252 Score = 28.9 bits (63), Expect = 3.1, Method: Compositional matrix adjust. Identities = 11/33 (33%), Positives = 21/33 (63%) Query: 228 KDFFQKMKETAVFINISRGDVVNQDDLYQALAS 260 KD + ++ +VF+N+S+G V ++DL A + Sbjct: 47 KDLDEVLQTHSVFVNVSKGQVAKKEDLISAFGT 79 >5G6R-A nrPDB Length = 295 Score = 28.9 bits (63), Expect = 3.5, Method: Compositional matrix adjust. Identities = 19/91 (20%), Positives = 39/91 (42%), Gaps = 1/91 (1%) Query: 156 VGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVA 215 +GI GLG +G A+A + G + ++ + E A+ ST ++ +++ Sbjct: 5 IGIFGLGAMGTALAAKYLEHGYKTSVWNRTTAKAIPLVEQGAKLASTISEGVNANDLIII 64 Query: 216 CSLTPATEGLCNKDFFQKMKETAVFINISRG 246 C L +D Q + + +N++ G Sbjct: 65 CLLNNQVVEDALRDALQTLPSKTI-VNLTNG 94 >4E21-A nrPDB Length = 358 Score = 28.9 bits (63), Expect = 3.6, Method: Compositional matrix adjust. Identities = 12/27 (44%), Positives = 19/27 (70%) Query: 156 VGIIGLGRIGQAIARRLKPFGVQRFLY 182 +G+IGLGR+G + RRL+ G + +Y Sbjct: 25 IGMIGLGRMGADMVRRLRKGGHECVVY 51 >4YPO-A nrPDB Length = 333 Score = 28.9 bits (63), Expect = 3.6, Method: Compositional matrix adjust. Identities = 26/71 (36%), Positives = 35/71 (49%), Gaps = 5/71 (7%) Query: 156 VGIIGLGRIGQAIARRLKPFGVQ--RFLYTGRQPRPEEAAEFQAEFVSTP-ELAAQSDFI 212 VG+IG G G A + L+ GVQ L G + RP+ E Q V TP E+A +D + Sbjct: 17 VGVIGYGSQGHAHSLSLRDSGVQVRVGLKQGSRSRPK--VEEQGLDVDTPAEVAKWADVV 74 Query: 213 VVACSLTPATE 223 +V T E Sbjct: 75 MVLAPDTAQAE 85 >4RG3-A nrPDB Length = 548 Score = 28.5 bits (62), Expect = 4.1, Method: Compositional matrix adjust. Identities = 23/76 (30%), Positives = 31/76 (40%), Gaps = 12/76 (15%) Query: 145 WLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPR-----------PEEAA 193 W G L VG+IG G GQ + L P V+ R P+ PE+ A Sbjct: 178 WPEGKSLAGRRVGVIGTGSTGQQVITSLAP-EVEHLTVFVRTPQYSVPVGNRPVNPEQIA 236 Query: 194 EFQAEFVSTPELAAQS 209 E +A++ E A S Sbjct: 237 EIKADYDRIWERAKNS 252 >5OCM-A nrPDB Length = 291 Score = 28.5 bits (62), Expect = 4.7, Method: Compositional matrix adjust. Identities = 18/61 (29%), Positives = 31/61 (50%) Query: 156 VGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVA 215 V ++GLG +GQA+A G ++ + + + AE A S+ AA++ +VV Sbjct: 6 VTVLGLGLMGQALAGAFLKDGHATTVWNRSEGKAGQLAEQGAVLASSARDAAEASPLVVV 65 Query: 216 C 216 C Sbjct: 66 C 66 >3H9U-A nrPDB Length = 436 Score = 28.1 bits (61), Expect = 4.9, Method: Compositional matrix adjust. Identities = 23/94 (24%), Positives = 37/94 (39%), Gaps = 4/94 (4%) Query: 154 STVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIV 213 T + G G +G+ A L+ FG R + T P A + V E + I Sbjct: 212 KTACVCGYGDVGKGCAAALRGFGA-RVVVTEVDPINALQAAMEGYQVLLVEDVVEEAHIF 270 Query: 214 VACSLTPATEGLCNKDFFQKMKETAVFINISRGD 247 V T + + + F +M++ A+ NI D Sbjct: 271 VT---TTGNDDIITSEHFPRMRDDAIVCNIGHFD 301 >5UKB-D nrPDB Length = 423 Score = 28.1 bits (61), Expect = 5.5, Method: Compositional matrix adjust. Identities = 12/36 (33%), Positives = 22/36 (61%) Query: 229 DFFQKMKETAVFINISRGDVVNQDDLYQALASGKIA 264 D+F+K KE ++IN ++ + +YQ L SG ++ Sbjct: 31 DYFRKSKEIPLYINTTKSLSDLRGYVYQGLKSGNVS 66 >4D3S-A nrPDB Length = 293 Score = 27.3 bits (59), Expect = 9.8, Method: Compositional matrix adjust. Identities = 17/51 (33%), Positives = 27/51 (52%) Query: 153 QSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTP 203 +S V +IGLG +GQA+A L G + ++ + + E AE A +P Sbjct: 8 KSPVTLIGLGPMGQAMAGALLEAGYELTVWNRTKAKAEALAERGAAVADSP 58 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2WWR-A nrPDB 424 e-119 5AOV-A nrPDB 375 e-104 6BII-A nrPDB 349 1e-96 2DBZ-A nrPDB 328 2e-90 4EBF-A nrPDB 322 1e-88 1GDH-A nrPDB 319 1e-87 2G76-A nrPDB 318 3e-87 4G2N-A nrPDB 315 2e-86 2D0I-A nrPDB 312 1e-85 6IH4-A nrPDB 300 6e-82 3KB6-A nrPDB 299 7e-82 1WWK-A nrPDB 299 1e-81 2CUK-A nrPDB 297 3e-81 3FN4-A nrPDB 297 5e-81 5TX7-A nrPDB 295 1e-80 4ZGS-A nrPDB 290 5e-79 2GO1-A nrPDB 289 7e-79 3WR5-A nrPDB 289 1e-78 3BA1-A nrPDB 284 4e-77 5Z1Z-A nrPDB 283 6e-77 6ABJ-A nrPDB 283 1e-76 4CUK-A nrPDB 280 4e-76 3JTM-A nrPDB 279 1e-75 1HL3-A nrPDB 277 6e-75 3DC2-A nrPDB 277 6e-75 2OME-A nrPDB 276 7e-75 6ABI-A nrPDB 273 7e-74 2PA3-A nrPDB 273 8e-74 2EKL-A nrPDB 271 4e-73 1DXY-A nrPDB 270 5e-73 3K5P-A nrPDB 269 1e-72 1J49-A nrPDB 267 4e-72 2DLD-A nrPDB 266 1e-71 4PRK-A nrPDB 265 2e-71 6D4C-A nrPDB 264 4e-71 4XYG-A nrPDB 262 1e-70 3HG7-A nrPDB 261 2e-70 4DGS-A nrPDB 255 2e-68 1XDW-A nrPDB 255 2e-68 3GG9-A nrPDB 254 3e-68 5OFW-B nrPDB 254 3e-68 4LSW-A nrPDB 254 4e-68 2YQ5-A nrPDB 251 3e-67 3WNV-A nrPDB 250 6e-67 2W2L-A nrPDB 243 9e-65 4S1V-D nrPDB 240 6e-64 5UOG-A nrPDB 235 2e-62 5MH6-A nrPDB 230 7e-61 3EVT-A nrPDB 229 1e-60 5DT9-A nrPDB 227 4e-60 4N18-A nrPDB 227 4e-60 4XKJ-A nrPDB 226 2e-59 5TSD-A nrPDB 217 4e-57 4XA8-A nrPDB 216 8e-57 4NFY-A nrPDB 216 1e-56 3OET-A nrPDB 215 2e-56 3KBO-A nrPDB 210 4e-55 4WEQ-A nrPDB 207 5e-54 4HY3-A nrPDB 200 6e-52 3GVX-A nrPDB 194 6e-50 5C5I-A nrPDB 194 6e-50 1QP8-A nrPDB 190 5e-49 2O4C-A nrPDB 180 9e-46 Sequences not found previously or not previously below threshold: 3H9U-A nrPDB 56 2e-08 5JXW-A nrPDB 55 4e-08 3G1U-A nrPDB 53 1e-07 3D64-A nrPDB 53 2e-07 6JCV-A nrPDB 52 3e-07 6GBN-A nrPDB 52 4e-07 3NJ4-A nrPDB 51 6e-07 2ZJ1-A nrPDB 51 8e-07 3N58-A nrPDB 49 3e-06 3X2F-A nrPDB 49 3e-06 3OND-A nrPDB 48 4e-06 5M65-A nrPDB 48 4e-06 6APH-A nrPDB 48 5e-06 1V8B-A nrPDB 48 6e-06 2RIR-A nrPDB 47 8e-06 5H82-A nrPDB 46 2e-05 2VHY-A nrPDB 45 3e-05 6C55-A nrPDB 45 5e-05 4XDY-A nrPDB 42 3e-04 4XDZ-A nrPDB 42 3e-04 5E4R-A nrPDB 42 3e-04 5U5G-A nrPDB 41 6e-04 2EEZ-A nrPDB 41 6e-04 4TSK-A nrPDB 41 8e-04 1X14-A nrPDB 41 8e-04 2GF2-A nrPDB 41 9e-04 4KQW-A nrPDB 40 0.001 4WJI-A nrPDB 40 0.002 4YPO-A nrPDB 40 0.002 5YEQ-A nrPDB 40 0.002 1V9L-A nrPDB 39 0.002 1VPD-A nrPDB 39 0.003 3B1F-A nrPDB 39 0.003 1GPJ-A nrPDB 39 0.003 1BVU-A nrPDB 39 0.004 3TWO-A nrPDB 38 0.005 5G6R-A nrPDB 38 0.007 6ACF-A nrPDB 37 0.010 2F1K-A nrPDB 37 0.010 1GTM-A nrPDB 37 0.011 3VPX-A nrPDB 36 0.014 4D3F-A nrPDB 36 0.016 2PV7-A nrPDB 36 0.018 6HD1-C nrPDB 36 0.023 3ABT-A nrPDB 36 0.023 5L3D-A nrPDB 36 0.030 4RG3-A nrPDB 36 0.031 1NPD-A nrPDB 35 0.038 3AOE-E nrPDB 35 0.039 6ER9-A nrPDB 35 0.040 3UP5-A nrPDB 35 0.042 5XVH-A nrPDB 35 0.048 3DZB-A nrPDB 35 0.051 2RCY-A nrPDB 35 0.054 5Y8M-A nrPDB 35 0.055 6F3O-A nrPDB 35 0.061 3PII-A nrPDB 35 0.071 6IQV-A nrPDB 34 0.081 4PZE-A nrPDB 34 0.083 3H9E-O nrPDB 34 0.083 2CZC-A nrPDB 34 0.088 3F9I-A nrPDB 34 0.095 4DIO-A nrPDB 34 0.098 3IHM-A nrPDB 34 0.099 4E21-A nrPDB 34 0.11 4OH1-A nrPDB 34 0.12 3ULK-A nrPDB 34 0.12 3UF0-A nrPDB 34 0.12 1CRW-G nrPDB 33 0.14 4DLA-A nrPDB 33 0.14 5T57-A nrPDB 33 0.16 5C7I-O nrPDB 33 0.17 6N7L-A nrPDB 33 0.19 5VDN-A nrPDB 33 0.20 1YB4-A nrPDB 33 0.20 3BIO-A nrPDB 33 0.22 3MOG-A nrPDB 33 0.24 6B4O-A nrPDB 33 0.25 4G65-A nrPDB 33 0.26 3FBG-A nrPDB 32 0.29 1CF2-P nrPDB 32 0.29 3UVE-A nrPDB 32 0.29 1EZ1-A nrPDB 32 0.30 3PEF-A nrPDB 32 0.30 3DOJ-A nrPDB 32 0.30 4K28-A nrPDB 32 0.31 2HK7-A nrPDB 32 0.32 1E3J-A nrPDB 32 0.32 4JJI-A nrPDB 32 0.33 1BG6-A nrPDB 32 0.36 1XLT-A nrPDB 32 0.36 3F3S-A nrPDB 32 0.37 1ZCJ-A nrPDB 32 0.39 1CER-O nrPDB 32 0.39 6BZ0-A nrPDB 32 0.41 4DLL-A nrPDB 32 0.41 4IZO-A nrPDB 32 0.42 3ZWA-A nrPDB 31 0.48 3PDU-A nrPDB 31 0.49 1JAY-A nrPDB 31 0.49 2O3A-A nrPDB 31 0.50 6DU7-A nrPDB 31 0.51 3AOE-A nrPDB 31 0.51 4XGI-A nrPDB 31 0.56 2X41-A nrPDB 31 0.57 2R9Z-A nrPDB 31 0.62 2VYN-D nrPDB 31 0.63 4OM8-A nrPDB 31 0.68 5OJG-A nrPDB 31 0.70 1H2H-A nrPDB 31 0.72 1A5Z-A nrPDB 31 0.72 3K8Z-A nrPDB 31 0.73 4YRY-B nrPDB 31 0.74 1VC2-A nrPDB 31 0.83 1Z82-A nrPDB 31 0.84 1PL8-A nrPDB 31 0.87 2HMT-A nrPDB 31 0.89 2Z04-A nrPDB 31 0.98 5BUT-A nrPDB 31 0.99 4R16-A nrPDB 31 0.99 6JDK-A nrPDB 31 1.0 5J9G-A nrPDB 30 1.1 3ZHB-A nrPDB 30 1.1 3VZS-A nrPDB 30 1.1 6AON-A nrPDB 30 1.2 5U8W-A nrPDB 30 1.2 2CZG-A nrPDB 30 1.3 1L1F-A nrPDB 30 1.3 4J90-A nrPDB 30 1.4 3OJO-A nrPDB 30 1.4 2DQ4-A nrPDB 30 1.4 3G0O-A nrPDB 30 1.5 3LK7-A nrPDB 30 1.5 3E5R-O nrPDB 30 1.5 3QE3-A nrPDB 30 1.5 3NDC-A nrPDB 30 1.5 1HYH-A nrPDB 30 1.6 3K92-A nrPDB 30 1.7 6FG0-A nrPDB 30 1.8 3FBT-A nrPDB 30 1.8 3EZY-A nrPDB 30 1.9 6N7F-A nrPDB 30 1.9 4EJ6-A nrPDB 30 2.0 3GGO-A nrPDB 30 2.0 4ILK-A nrPDB 30 2.0 5TR3-A nrPDB 30 2.1 4BO1-A nrPDB 30 2.1 3IP1-A nrPDB 30 2.1 4FHN-X nrPDB 30 2.1 6DKH-A nrPDB 30 2.1 5Y77-A nrPDB 30 2.3 4Z0H-O nrPDB 30 2.3 2G5C-A nrPDB 29 2.3 6HRD-A nrPDB 29 2.4 1LLU-A nrPDB 29 2.4 6DHM-A nrPDB 29 2.5 1VSU-A nrPDB 29 2.6 4OQZ-A nrPDB 29 2.7 2YFH-A nrPDB 29 3.1 5FI5-A nrPDB 29 3.2 1GEU-A nrPDB 29 3.3 3ADO-A nrPDB 29 3.4 5XW0-A nrPDB 29 3.4 3RWB-A nrPDB 29 3.4 5N2I-A nrPDB 29 3.5 4UEJ-A nrPDB 29 3.5 3WYB-A nrPDB 29 3.7 2VCY-A nrPDB 29 3.7 5U1O-A nrPDB 29 3.8 1WDE-A nrPDB 28 4.0 3IC9-A nrPDB 28 4.1 5ZZ6-A nrPDB 28 4.2 2NVK-X nrPDB 28 4.2 3LAD-A nrPDB 28 4.8 4AP1-A nrPDB 28 5.1 4AYX-A nrPDB 28 5.3 3S2F-A nrPDB 28 5.4 2WNI-A nrPDB 28 5.4 1N5W-C nrPDB 28 5.4 3MJ4-A nrPDB 28 5.5 4B1B-A nrPDB 28 5.7 6BPF-A nrPDB 28 5.8 5T5Q-A nrPDB 28 6.0 1XCB-A nrPDB 28 6.0 4E4T-A nrPDB 28 6.2 3GRP-A nrPDB 28 6.2 3WTC-A nrPDB 28 6.9 4DYD-A nrPDB 28 7.2 1PJB-A nrPDB 28 7.4 5KSD-A nrPDB 28 7.6 6MGG-A nrPDB 28 7.7 3X43-A nrPDB 28 8.2 3L60-A nrPDB 28 8.5 2DC1-A nrPDB 27 9.1 2ZCU-A nrPDB 27 9.2 2UVD-A nrPDB 27 9.3 >2WWR-A nrPDB Length = 330 Score = 424 bits (1090), Expect = e-119, Method: Composition-based stats. Identities = 328/328 (100%), Positives = 328/328 (100%) Query: 1 MRPVRLMKVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLS 60 MRPVRLMKVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLS Sbjct: 3 MRPVRLMKVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLS 62 Query: 61 DHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLL 120 DHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLL Sbjct: 63 DHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLL 122 Query: 121 TTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRF 180 TTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRF Sbjct: 123 TTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRF 182 Query: 181 LYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVF 240 LYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVF Sbjct: 183 LYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVF 242 Query: 241 INISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHR 300 INISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHR Sbjct: 243 INISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHR 302 Query: 301 TRNTMSLLAANNLLAGLRGEPMPSELKL 328 TRNTMSLLAANNLLAGLRGEPMPSELKL Sbjct: 303 TRNTMSLLAANNLLAGLRGEPMPSELKL 330 >5AOV-A nrPDB Length = 336 Score = 375 bits (964), Expect = e-104, Method: Composition-based stats. Identities = 132/331 (39%), Positives = 191/331 (57%), Gaps = 13/331 (3%) Query: 1 MRPVRLMKVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLS 60 M+P KVF+TR IP G L EVE W+ + IP ++L V L+ +LS Sbjct: 1 MKP----KVFITRAIPENGINMLEEEF--EVEVWEEEREIPREKLLEKVKDVDALVTMLS 54 Query: 61 DHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLL 120 + +D+ + + A L++++ +VG D++ ++E +RGI V TPDVLT+ TA+ A +LLL Sbjct: 55 ERIDQEVFENA-PRLRIVANYAVGYDNIDVEEATRRGIYVTNTPDVLTNATADHAFALLL 113 Query: 121 TTCRRLPEAIEEVKNGGWTS----WKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFG 176 T R + + + V++G W W P W GY L T+GI+G GRIGQAIARR K F Sbjct: 114 ATARHVVKGDKFVRSGEWKRKGIAWHPKWFLGYELYGKTIGIVGFGRIGQAIARRAKGFN 173 Query: 177 VQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKE 236 ++ Y+ R + + E AE+ E+ +SDF+++A LT T + N++ + MK Sbjct: 174 MRILYYS-RTRKSQAEKELGAEYRPLEEVLKESDFVILAVPLTKETMYMINEERLKLMKP 232 Query: 237 TAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGS 296 TA+ +NI+RG VV+ L +AL G IA AGLDV EP N L +L N V+ PHIGS Sbjct: 233 TAILVNIARGKVVDTKALIKALKEGWIAGAGLDVFEEEPY-YNEELFSLDNVVLTPHIGS 291 Query: 297 ATHRTRNTMSLLAANNLLAGLRGEPMPSELK 327 AT R M+ L A NL+A RGE P+ + Sbjct: 292 ATFEAREAMAELVARNLIAFKRGEIPPTLVN 322 >6BII-A nrPDB Length = 333 Score = 349 bits (895), Expect = 1e-96, Method: Composition-based stats. Identities = 138/331 (41%), Positives = 190/331 (57%), Gaps = 13/331 (3%) Query: 1 MRPVRLMKVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLS 60 M+P KV +TR IP G L EVE W+ + IP + L V L+ +LS Sbjct: 1 MKP----KVLITRAIPENGIELLRE--HFEVEVWEHEHEIPREVLLEKVKDVDALVTMLS 54 Query: 61 DHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLL 120 + +D+ + DAA L++++ +VG D++ ++E KRGI V TPDVLTD TA+LA +LLL Sbjct: 55 EKIDREVFDAA-PRLRIVANYAVGYDNIDIEEATKRGIYVTNTPDVLTDATADLAWALLL 113 Query: 121 TTCRRLPEAIEEVKNGGWTS----WKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFG 176 R + + + V++G W W P GY + T+GI+G GRIGQAIA+R K FG Sbjct: 114 AAARHVVKGDKFVRSGEWKRRGIAWHPKMFLGYDVYGKTIGIVGFGRIGQAIAKRAKGFG 173 Query: 177 VQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKE 236 ++ YT R +PE E AEF EL +SDF+V+A LT T + N++ + MK Sbjct: 174 MRIL-YTARSRKPEAEKELGAEFKPLEELLRESDFVVLAVPLTKETYHMINEERLRLMKP 232 Query: 237 TAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGS 296 TAV +N++RG VV+ L +AL G IAAAGLDV EP + L L N V+ PHIGS Sbjct: 233 TAVLVNVARGKVVDTKALIRALKEGWIAAAGLDVFEEEPY-YDEELFALDNVVLTPHIGS 291 Query: 297 ATHRTRNTMSLLAANNLLAGLRGEPMPSELK 327 AT R M+ L A NL+A GE P+ + Sbjct: 292 ATFGAREGMAELVAKNLIAFKNGEVPPTLVN 322 >2DBZ-A nrPDB Length = 334 Score = 328 bits (842), Expect = 2e-90, Method: Composition-based stats. Identities = 140/331 (42%), Positives = 194/331 (58%), Gaps = 13/331 (3%) Query: 1 MRPVRLMKVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLS 60 M+P KVF+TR IP G L + EVE W ++ IP + L + V L+ +LS Sbjct: 1 MKP----KVFITREIPEVGIKMLE--DEFEVEVWGDEKEIPREILLKKVKEVDALVTMLS 54 Query: 61 DHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLL 120 + +DK + + A L++++ +VG D++ ++E KRGI V TPDVLTD TA+LA +LLL Sbjct: 55 ERIDKEVFENA-PKLRIVANYAVGYDNIDIEEATKRGIYVTNTPDVLTDATADLAFALLL 113 Query: 121 TTCRRLPEAIEEVKNGGWTS----WKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFG 176 T R + + V++G W W P W GY + T+GIIGLGRIGQAIA+R K F Sbjct: 114 ATARHVVKGDRFVRSGEWKKRGVAWHPKWFLGYDVYGKTIGIIGLGRIGQAIAKRAKGFN 173 Query: 177 VQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKE 236 ++ Y+ R + E E AEF +L +SDF+V+A LT T L N++ + MK+ Sbjct: 174 MRILYYS-RTRKEEVERELNAEFKPLEDLLRESDFVVLAVPLTRETYHLINEERLKLMKK 232 Query: 237 TAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGS 296 TA+ INI+RG VV+ + L +AL G IA AGLDV EP N L L N V+ PHIGS Sbjct: 233 TAILINIARGKVVDTNALVKALKEGWIAGAGLDVFEEEPY-YNEELFKLDNVVLTPHIGS 291 Query: 297 ATHRTRNTMSLLAANNLLAGLRGEPMPSELK 327 A+ R M+ L A NL+A RGE P+ + Sbjct: 292 ASFGAREGMAELVAKNLIAFKRGEIPPTLVN 322 >4EBF-A nrPDB Length = 334 Score = 322 bits (826), Expect = 1e-88, Method: Composition-based stats. Identities = 101/329 (30%), Positives = 154/329 (46%), Gaps = 11/329 (3%) Query: 6 LMKVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLSDHVDK 65 L K+ +T R+ E L A CE+ +D + +E+ R A ++ + D VD Sbjct: 3 LPKLVITHRVHEEILQLL--APHCELITNQTDSTLTREEILRRCRDAQAMMAFMPDRVDA 60 Query: 66 RILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRR 125 L A L+VI G D+ +D RG+ + + PD+LT TAELA+ L + R Sbjct: 61 DFLQAC-PELRVIGCALKGFDNFDVDACTARGVWLTFVPDLLTVPTAELAIGLAVGLGRH 119 Query: 126 LPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGR 185 L A V++G + W+P + G GL +TVG +G+G IG A+A RL+ +G + + Sbjct: 120 LRAADAFVRSGQFRGWQPRFY-GTGLDNATVGFLGMGAIGLAMADRLQGWGATLQYHAAK 178 Query: 186 QPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISR 245 + V+ EL A SDFI++A L T L N + ++ A+ +N R Sbjct: 179 ALDTQTEQRLGLRQVACSELFASSDFILLALPLNADTLHLVNAELLALVRPGALLVNPCR 238 Query: 246 GDVVNQDDLYQALASGKIAAAGLDVTSPE-------PLPTNHPLLTLKNCVILPHIGSAT 298 G VV++ + AL G++ DV E P + LL N + PHIGSA Sbjct: 239 GSVVDEAAVLAALERGQLGGYAADVFEMEDWARADRPQQIDPALLAHPNTLFTPHIGSAV 298 Query: 299 HRTRNTMSLLAANNLLAGLRGEPMPSELK 327 R + AA N+L L GE + + Sbjct: 299 RAVRLEIERCAAQNILQALAGERPINAVN 327 >1GDH-A nrPDB Length = 320 Score = 319 bits (817), Expect = 1e-87, Method: Composition-based stats. Identities = 108/314 (34%), Positives = 161/314 (51%), Gaps = 7/314 (2%) Query: 8 KVFVTRRIPAEGRVALARAADCEVEQWDSDEP-IPAKELERGVAGAHGLLCLLSDHVDKR 66 K+ +T +P +ARA + D+P I E+ LL L++ K Sbjct: 3 KILITWPLPEAA---MARARESYDVIAHGDDPKITIDEMIETAKSVDALLITLNEKCRKE 59 Query: 67 ILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRL 126 ++D N+K IST S+G DH+ LD K RGI+VG P +T TAE+A+ LLL + RR Sbjct: 60 VIDRIPENIKCISTYSIGFDHIDLDACKARGIKVGNAPHGVTVATAEIAMLLLLGSARRA 119 Query: 127 PEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQ 186 E + ++ W W+PL L G L T+GI G G IGQA+A+R + F + + + Sbjct: 120 GEGEKMIRTRSWPGWEPLELVGEKLDNKTLGIYGFGSIGQALAKRAQGFDMDIDYFDTHR 179 Query: 187 PRPEEAAEFQAEFV-STPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISR 245 + A +QA F S L + S F + TP T NK + + + A+ +N +R Sbjct: 180 ASSSDEASYQATFHDSLDSLLSVSQFFSLNAPSTPETRYFFNKATIKSLPQGAIVVNTAR 239 Query: 246 GDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTM 305 GD+V+ + + AL +G++A AG DV + EP N L N + PHIGSA + R M Sbjct: 240 GDLVDNELVVAALEAGRLAYAGFDVFAGEP-NINEGYYDLPNTFLFPHIGSAATQAREDM 298 Query: 306 SLLAANNLLAGLRG 319 + AN+L+ L G Sbjct: 299 A-HQANDLIDALFG 311 >2G76-A nrPDB Length = 335 Score = 318 bits (814), Expect = 3e-87, Method: Composition-based stats. Identities = 91/317 (28%), Positives = 160/317 (50%), Gaps = 10/317 (3%) Query: 6 LMKVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLSDHVDK 65 L KV ++ + R L Q + + +EL + GL+ + V Sbjct: 26 LRKVLISDSLDPCCRKILQDGG----LQVVEKQNLSKEELIAELQDCEGLIVRSATKVTA 81 Query: 66 RILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRR 125 +++AA L+V+ G+D++ L+ ++GI V TP+ + + AEL +++ R+ Sbjct: 82 DVINAA-EKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQ 140 Query: 126 LPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGR 185 +P+A +K+G W K G L T+GI+GLGRIG+ +A R++ FG++ Y Sbjct: 141 IPQATASMKDGKWERKK---FMGTELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPI 197 Query: 186 QPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISR 245 PE +A F + + E+ DFI V L P+T GL N + F + K+ +N +R Sbjct: 198 -ISPEVSASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCAR 256 Query: 246 GDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTM 305 G +V++ L +AL SG+ A A LDV + EP P + L+ +N + PH+G++T ++ Sbjct: 257 GGIVDEGALLRALQSGQCAGAALDVFTEEP-PRDRALVDHENVISCPHLGASTKEAQSRC 315 Query: 306 SLLAANNLLAGLRGEPM 322 A + ++G+ + Sbjct: 316 GEEIAVQFVDMVKGKSL 332 >4G2N-A nrPDB Length = 345 Score = 315 bits (807), Expect = 2e-86, Method: Composition-based stats. Identities = 114/324 (35%), Positives = 162/324 (50%), Gaps = 4/324 (1%) Query: 1 MRPVRLMKVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLS 60 M + K F+ RR L + D EV D+ + + GA L + Sbjct: 23 MSTHPIQKAFLCRRFTPAIEAELRQRFDLEVNLEDT--VLTPSGIASRAHGAEVLFVTAT 80 Query: 61 DHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLL 120 + + ++ LK I+T+SVG DH+ + + GI+V +TPDVL+D AE+A+ L+L Sbjct: 81 EAITAEVIRKLQPGLKTIATLSVGYDHIDMAAARSLGIKVLHTPDVLSDACAEIAMLLVL 140 Query: 121 TTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRF 180 CRR EA V++G W W P L G GLT +GI G+GRIG+AIA R + FG+ Sbjct: 141 NACRRGYEADRMVRSGSWPGWGPTQLLGMGLTGRRLGIFGMGRIGRAIATRARGFGLA-I 199 Query: 181 LYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVF 240 Y R E + L SD ++A P +G + D K+ E AV Sbjct: 200 HYHNRTRLSHALEEGAIYHDTLDSLLGASDIFLIAAPGRPELKGFLDHDRIAKIPEGAVV 259 Query: 241 INISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHR 300 INISRGD++N D L +AL S + AAGLDV + EP + +L N + PHIGSATH Sbjct: 260 INISRGDLINDDALIEALRSKHLFAAGLDVFANEP-AIDPRYRSLDNIFLTPHIGSATHE 318 Query: 301 TRNTMSLLAANNLLAGLRGEPMPS 324 TR+ M L + A + + + Sbjct: 319 TRDAMGWLLIQGIEALNQSDVPDN 342 >2D0I-A nrPDB Length = 333 Score = 312 bits (800), Expect = 1e-85, Method: Composition-based stats. Identities = 102/331 (30%), Positives = 161/331 (48%), Gaps = 17/331 (5%) Query: 1 MRPVRLMKVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLS 60 MRP KV V ++ E L + AD E+ + S E EL+ + G++ + Sbjct: 1 MRP----KVGVLLKMKREALEELKKYADVEIILYPSGE-----ELKGVIGRFDGIIVSPT 51 Query: 61 DHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLL 120 + + +L+ A LKVIS S G D++ L+E KRGI V +L++ AE V L++ Sbjct: 52 TKITREVLENA-ERLKVISCHSAGYDNIDLEEATKRGIYVTKVSGLLSEAVAEFTVGLII 110 Query: 121 TTCRRLPEAIEEVKNGGWTSWKPLWLCGY---GLTQSTVGIIGLGRIGQAIARRLKPFGV 177 R++ A + ++ G W S +W L VGI+G+G IG+AIARRL PFGV Sbjct: 111 NLMRKIHYADKFIRRGEWESHAKIWTGFKRIESLYGKKVGILGMGAIGKAIARRLIPFGV 170 Query: 178 QRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKET 237 + Y R + E +A ++ EL +SD +++A LT T + N++ +K+ E Sbjct: 171 K-LYYWSRHRKVNVEKELKARYMDIDELLEKSDIVILALPLTRDTYHIINEERVKKL-EG 228 Query: 238 AVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKN-CVILPHIGS 296 +NI RG +V++ + +A+ GK+ DV EP+ H L + V+ PH Sbjct: 229 KYLVNIGRGALVDEKAVTEAIKQGKLKGYATDVFEKEPV-REHELFKYEWETVLTPHYAG 287 Query: 297 ATHRTRNTMSLLAANNLLAGLRGEPMPSELK 327 + + A NLL LRGE + Sbjct: 288 LALEAQEDVGFRAVENLLKVLRGEVPEDLVN 318 >6IH4-A nrPDB Length = 338 Score = 300 bits (768), Expect = 6e-82, Method: Composition-based stats. Identities = 100/335 (29%), Positives = 154/335 (45%), Gaps = 16/335 (4%) Query: 1 MRPVRLMKVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLS 60 M+P KV +T + E L+ +AD V + E +P E+ A L+ + Sbjct: 1 MKP----KVVLTHWVHPEIIELLSASAD--VIPNTTRETLPRSEVIARAKDADALMAFMP 54 Query: 61 DHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLL 120 D +D L+ L+VI G D+ ++ + G+ + PD+LT TAEL + LLL Sbjct: 55 DSIDSAFLEEC-PKLRVIGAALKGYDNFDVNACTRHGVWLTIVPDLLTIPTAELTIGLLL 113 Query: 121 TTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRF 180 R + E ++++G + W+P L G GLT T+GI G+G +G+AIA+RL F + Sbjct: 114 GLTRHMLEGDRQIRSGHFQGWRPT-LYGSGLTGKTLGIRGMGAVGRAIAQRLAGFEMNLL 172 Query: 181 LYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVF 240 E+ + + V+ EL + D++V + T L + KMK + Sbjct: 173 YCDEIPLNAEQEKAWHVQRVTLDELLEKCDYVVPMVPMAAETLHLIDATALAKMKTGSYL 232 Query: 241 INISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPL-----PTNHPLLTLKN---CVILP 292 IN RG VV+++ + ALASGK+A DV E P P L N P Sbjct: 233 INACRGSVVDENAVIAALASGKLAGYAADVFEMEEWIRADRPQAIPKALLDNTAQTFFTP 292 Query: 293 HIGSATHRTRNTMSLLAANNLLAGLRGEPMPSELK 327 H+GSA R + AA N++ L GE + Sbjct: 293 HLGSAVKEVRLEIERQAAMNIIQALAGEKPMGAIN 327 >3KB6-A nrPDB Length = 334 Score = 299 bits (767), Expect = 7e-82, Method: Composition-based stats. Identities = 90/329 (27%), Positives = 145/329 (44%), Gaps = 25/329 (7%) Query: 7 MKVFVTRRIPAEGRVALARAADCEVEQWDSD-EPIPAKELERGVAGAHGLLCLLSDHVDK 65 M V T + D ++ + +D +P EL++ A + + D + + Sbjct: 1 MNVLFTSVPQEDVPFYQEALKDLSLKIYTTDVSKVPENELKK----AELISVFVYDKLTE 56 Query: 66 RILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRR 125 +L LK+I T SVG DH+ LD KK+GI V + P ++ AE +++LT +R Sbjct: 57 ELLSKM-PRLKLIHTRSVGFDHIDLDYCKKKGILVTHIPAYSPESVAEHTFAMILTLVKR 115 Query: 126 LPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGR 185 L + VK ++ + L + T+G+IG GRIG +A FG++ Y Sbjct: 116 LKRIEDRVKKLNFSQDSEI--LARELNRLTLGVIGTGRIGSRVAMYGLAFGMKVLCYDV- 172 Query: 186 QPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISR 245 + E+ E + S EL +SD I + T T + N++ MK+ IN +R Sbjct: 173 -VKREDLKEKGCVYTSLDELLKESDVISLHVPYTKETHHMINEERISLMKDGVYLINTAR 231 Query: 246 GDVVNQDDLYQALASGKIAAAGLDVTSPEPL----------PTNHPLLTL-----KNCVI 290 G VV+ D LY+A GK + GLDV E + T+ L L N +I Sbjct: 232 GKVVDTDALYRAYQRGKFSGLGLDVFEDEEILILKKYTEGKATDKNLKILELACKDNVII 291 Query: 291 LPHIGSATHRTRNTMSLLAANNLLAGLRG 319 PHI T ++ + + A ++G Sbjct: 292 TPHIAYYTDKSLERIREETVKVVKAFVKG 320 >1WWK-A nrPDB Length = 307 Score = 299 bits (766), Expect = 1e-81, Method: Composition-based stats. Identities = 103/313 (32%), Positives = 158/313 (50%), Gaps = 9/313 (2%) Query: 7 MKVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLSDHVDKR 66 MKV V + + L A EV +E L V ++ V +R Sbjct: 4 MKVLVAAPLHEKAIQVLKDAG-LEVI---YEEYPDEDRLVELVKDVEAIIVRSKPKVTRR 59 Query: 67 ILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRL 126 ++++A LKVI+ VG+D++ ++ K++GI V P + + AELAV L+ + R++ Sbjct: 60 VIESA-PKLKVIARAGVGLDNIDVEAAKEKGIEVVNAPAASSRSVAELAVGLMFSVARKI 118 Query: 127 PEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQ 186 A +++ G W + + G L T+GIIG GRIG +A+ G+ LY Sbjct: 119 AFADRKMREGVWAKKEAM---GIELEGKTIGIIGFGRIGYQVAKIANALGMNILLYDPY- 174 Query: 187 PRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRG 246 P E A E +FV L +SD + + L +T L N++ + MK+TA+ IN SRG Sbjct: 175 PNEERAKEVNGKFVDLETLLKESDVVTIHVPLVESTYHLINEERLKLMKKTAILINTSRG 234 Query: 247 DVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTMS 306 VV+ + L +AL G IA AGLDV EPLP +HPL N V+ PHIG++T + Sbjct: 235 PVVDTNALVKALKEGWIAGAGLDVFEEEPLPKDHPLTKFDNVVLTPHIGASTVEAQERAG 294 Query: 307 LLAANNLLAGLRG 319 + A ++ L+G Sbjct: 295 VEVAEKVVKILKG 307 >2CUK-A nrPDB Length = 311 Score = 297 bits (761), Expect = 3e-81, Method: Composition-based stats. Identities = 132/321 (41%), Positives = 187/321 (58%), Gaps = 12/321 (3%) Query: 7 MKVFVTRRIPAEGRVAL-ARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLSDHVDK 65 M+V VTR +P + L R + EV + +P EL + V GA GL+ + D +D Sbjct: 1 MRVLVTRTLPGKALDRLRERGLEVEVHRGLF---LPKAELLKRVEGAVGLIPTVEDRIDA 57 Query: 66 RILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRR 125 ++D A LKVI+ SVG+DH+ L+ ++RGIRV +TP VLT+ TA+L ++LLL RR Sbjct: 58 EVMDRA-KGLKVIACYSVGVDHVDLEAARERGIRVTHTPGVLTEATADLTLALLLAVARR 116 Query: 126 LPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGR 185 + E ++G W +W P L G L T+G++G+GRIGQA+A+R FG++ Y R Sbjct: 117 VVEGAAYARDGLWKAWHPELLLGLDLQGLTLGLVGMGRIGQAVAKRALAFGMRVV-YHAR 175 Query: 186 QPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISR 245 P+P F+S EL ++D + + LTP T L N++ MK A+ +N +R Sbjct: 176 TPKP-----LPYPFLSLEELLKEADVVSLHTPLTPETHRLLNRERLFAMKRGAILLNTAR 230 Query: 246 GDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTM 305 G +V+ + L +AL G + AGLDVT PEPLP HPL L N VI PHIGSA TR M Sbjct: 231 GALVDTEALVEALR-GHLFGAGLDVTDPEPLPPGHPLYALPNAVITPHIGSAGRTTRERM 289 Query: 306 SLLAANNLLAGLRGEPMPSEL 326 + +A NLLA L G P+ + Sbjct: 290 AEVAVENLLAVLEGREPPNPV 310 >3FN4-A nrPDB Length = 401 Score = 297 bits (760), Expect = 5e-81, Method: Composition-based stats. Identities = 78/313 (24%), Positives = 133/313 (42%), Gaps = 9/313 (2%) Query: 19 GRVALARAADCEVE--QWDSDEPIPAKELERGVAGAHGLL--CLLSDHVDKRILDAAGAN 74 G + L + + + S + P ELE+ + A ++ ++ + A Sbjct: 55 GELGLRKYLESQGHELVVTSSKDGPDSELEKHLHDAEVIISQPFWPAYLTAERI-AKAPK 113 Query: 75 LKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVK 134 LK+ T +G DH+ L I V +++ AE V ++L R + + + Sbjct: 114 LKLALTAGIGSDHVDLQAAIDNNITVAEVTYCNSNSVAEHVVMMVLGLVRNYIPSHDWAR 173 Query: 135 NGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEE-AA 193 NGGW + Y + VG + GRIG + R L PF + YT R PE Sbjct: 174 NGGWNIADCVA-RSYDVEGMHVGTVAAGRIGLRVLRLLAPFDMH-LHYTDRHRLPEAVEK 231 Query: 194 EFQAEFVST-PELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQD 252 E + +T ++ D + + C L P TE + N + + K A +N +RG + ++D Sbjct: 232 ELNLTWHATREDMYGACDVVTLNCPLHPETEHMINDETLKLFKRGAYLVNTARGKLCDRD 291 Query: 253 DLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTMSLLAANN 312 + +AL SG++A DV P+P P +HP T+ + + PHI + + + Sbjct: 292 AIVRALESGRLAGYAGDVWFPQPAPNDHPWRTMPHNGMTPHISGTSLSAQTRYAAGTREI 351 Query: 313 LLAGLRGEPMPSE 325 L G P+ E Sbjct: 352 LECYFEGRPIRDE 364 >5TX7-A nrPDB Length = 327 Score = 295 bits (756), Expect = 1e-80, Method: Composition-based stats. Identities = 89/285 (31%), Positives = 138/285 (48%), Gaps = 7/285 (2%) Query: 41 PAKELERGVAGAHGLLCLLSDHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRV 100 P+ ++ AGAH ++ +D L A L+ +S ++ G D + + GI V Sbjct: 35 PSDKIIERAAGAH-VVLTNKVPLDMSALQAL-PGLRFVSVLATGYDKVDVAAAGVLGIPV 92 Query: 101 GYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTS---WKPLWLCGYGLTQSTVG 157 P TD+ A+ +LLL CRR ++ G WT W LT T+G Sbjct: 93 SNVPGYGTDSVAQHVFALLLELCRRTALHDHRIRAGAWTQSPDWCFWDSTQEELTGKTMG 152 Query: 158 IIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACS 217 I+G G G+ + R G+ Y R + F E V EL +D + + C Sbjct: 153 IVGFGNTGRRVGRIANALGMNVIAYAPRSRFDPDYRPF--EHVGLDELFTSADVVSLHCP 210 Query: 218 LTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLP 277 LTP TEGL + M+ + IN +RG ++++ + +AL SG++A AGLDV S EP Sbjct: 211 LTPETEGLVDARRLASMRPGSYLINTARGPLLDERAVAEALDSGRLAGAGLDVLSQEPPA 270 Query: 278 TNHPLLTLKNCVILPHIGSATHRTRNTMSLLAANNLLAGLRGEPM 322 ++PLL+ KNC+I PH+ A+ R T+ A N+ + + G P+ Sbjct: 271 ADNPLLSAKNCLITPHLAWASRTARRTLMDSTAANIRSFIEGTPV 315 >4ZGS-A nrPDB Length = 386 Score = 290 bits (743), Expect = 5e-79, Method: Composition-based stats. Identities = 92/310 (29%), Positives = 142/310 (45%), Gaps = 25/310 (8%) Query: 38 EPIPAKELERGVAGAHGLLCLLSDHVDKRIL-DAAGANLKVISTMSVGIDHLALDEIKKR 96 EP K+ + G + ++D D ++ + A A +K+I+ G D + L + Sbjct: 65 EPPLDKDTAQLARGYDVAVLFVNDRADASVIKELAKAGVKLIALRCAGFDRVDLHACAEH 124 Query: 97 GIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTV 156 G+RV P ++ AE AV+L+ R L +A V+ G ++ L G + V Sbjct: 125 GVRVVRVPTYSPESVAEHAVALIFALNRHLTDAYIRVRMGNYSL---SGLVGVEMRHKVV 181 Query: 157 GIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVAC 216 G++G G IGQ AR LK G + F Y + P P A +VS EL A SD + + C Sbjct: 182 GVVGTGAIGQQAARILKGIGCKVFAYDIK-PNPAVEA-MGIPYVSLDELLAMSDIVTLHC 239 Query: 217 SLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEP- 275 L P+T L NK+ QKMK+ + IN+SRG +++ L+ AL SG+I A GLDV E Sbjct: 240 PLLPSTRQLINKESIQKMKKGVMLINVSRGGLIDSAALFDALESGQIGALGLDVYENEGG 299 Query: 276 -LPTNH-----------------PLLTLKNCVILPHIGSATHRTRNTMSLLAANNLLAGL 317 +H LL+ ++ PH T N + N+ + Sbjct: 300 LFFVDHTKFDPSVRMQKWDRQFRTLLSYPQVLVTPHTAFLTEEALNNICTTTIQNIADYV 359 Query: 318 RGEPMPSELK 327 P+ +E+K Sbjct: 360 LDRPLGNEVK 369 >2GO1-A nrPDB Length = 401 Score = 289 bits (741), Expect = 7e-79, Method: Composition-based stats. Identities = 82/297 (27%), Positives = 128/297 (43%), Gaps = 7/297 (2%) Query: 33 QWDSDEPIPAKELERGVAGAHGLL--CLLSDHVDKRILDAAGANLKVISTMSVGIDHLAL 90 SD+ P ER + A ++ ++ + A NLK+ T +G DH+ L Sbjct: 72 VVTSDKDGPDSVFERELVDADVVISQPFWPAYLTPERI-AKAKNLKLALTAGIGSDHVDL 130 Query: 91 DEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYG 150 R + V + + AE V ++L+ R + E + GGW + Y Sbjct: 131 QSAIDRNVTVAEVTYCNSISVAEHVVMMILSLVRNYLPSHEWARKGGWNIADCVSH-AYD 189 Query: 151 LTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPE-EAAEFQAEFVST-PELAAQ 208 L VG + GRIG A+ RRL PF V YT R PE E + +T ++ Sbjct: 190 LEAMHVGTVAAGRIGLAVLRRLAPFDVH-LHYTDRHRLPESVEKELNLTWHATREDMYPV 248 Query: 209 SDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGL 268 D + + C L P TE + N + + K A +N +RG + ++D + +AL SG++A Sbjct: 249 CDVVTLNCPLHPETEHMINDETLKLFKRGAYIVNTARGKLCDRDAVARALESGRLAGYAG 308 Query: 269 DVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTMSLLAANNLLAGLRGEPMPSE 325 DV P+P P +HP T+ + PHI T + + L G P+ E Sbjct: 309 DVWFPQPAPKDHPWRTMPYNGMTPHISGTTLTAQARYAAGTREILECFFEGRPIRDE 365 >3WR5-A nrPDB Length = 406 Score = 289 bits (740), Expect = 1e-78, Method: Composition-based stats. Identities = 84/310 (27%), Positives = 130/310 (41%), Gaps = 9/310 (2%) Query: 20 RVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLL--CLLSDHVDKRILDAAGANLKV 77 R L V D D P E+ + A ++ ++ + A NLK+ Sbjct: 66 RKYLEANGHTFVVTSDKDG--PDSVFEKELVDADVVISQPFWPAYLTPERI-AKAKNLKL 122 Query: 78 ISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGG 137 T +G DH+ L RGI V + + AE V ++L R + + + GG Sbjct: 123 ALTAGIGSDHVDLQSAIDRGITVAEVTYCNSISVAEHVVMMILGLVRNYIPSHDWARKGG 182 Query: 138 WTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEE-AAEFQ 196 W Y L TVG + GRIG A+ RRL PF V+ YT R PE E Sbjct: 183 WNI-ADCVEHSYDLEGMTVGSVAAGRIGLAVLRRLAPFDVK-LHYTDRHRLPEAVEKELG 240 Query: 197 AEFVST-PELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLY 255 + T ++ D + + L P TE + N + + K A +N +RG + ++D + Sbjct: 241 LVWHDTREDMYPHCDVVTLNVPLHPETEHMINDETLKLFKRGAYIVNTARGKLADRDAIV 300 Query: 256 QALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTMSLLAANNLLA 315 +A+ SG++A DV P+P P +HP T+K + PHI + + + L Sbjct: 301 RAIESGQLAGYAGDVWFPQPAPKDHPWRTMKWEGMTPHISGTSLSAQARYAAGTREILEC 360 Query: 316 GLRGEPMPSE 325 G P+ E Sbjct: 361 FFEGRPIRDE 370 >3BA1-A nrPDB Length = 333 Score = 284 bits (727), Expect = 4e-77, Method: Composition-based stats. Identities = 105/325 (32%), Positives = 161/325 (49%), Gaps = 9/325 (2%) Query: 2 RPVRLMKVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLSD 61 R + + V P + ++ ++ + +P L ++ + Sbjct: 17 RGSHMEAIGVLMMCPMSTYLEQELDKRFKLFRYWT-QPAQRDFLALQAESIRAVVGNSNA 75 Query: 62 HVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLT 121 D ++DA L+++S+ SVG+D + L + +++G+RV TPDVLTD A+LA+ L+L Sbjct: 76 GADAELIDAL-PKLEIVSSFSVGLDKVDLIKCEEKGVRVTNTPDVLTDDVADLAIGLILA 134 Query: 122 TCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFL 181 RR+ E + V+ G W + + VGIIGLGRIG A+A R + F Sbjct: 135 VLRRICECDKYVRRGAWKFGD--FKLTTKFSGKRVGIIGLGRIGLAVAERAEAFDCP-IS 191 Query: 182 YTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFI 241 Y R +P + V ELA+ SD +VVAC LTP T + N++ + V I Sbjct: 192 YFSRSKKPNTNYTYYGSVV---ELASNSDILVVACPLTPETTHIINREVIDALGPKGVLI 248 Query: 242 NISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRT 301 NI RG V++ +L AL G++ AGLDV EP L L+N V+LPH+GS T T Sbjct: 249 NIGRGPHVDEPELVSALVEGRLGGAGLDVFEREPE-VPEKLFGLENVVLLPHVGSGTVET 307 Query: 302 RNTMSLLAANNLLAGLRGEPMPSEL 326 R M+ L NL A G+P+ + + Sbjct: 308 RKVMADLVVGNLEAHFSGKPLLTPV 332 >5Z1Z-A nrPDB Length = 329 Score = 283 bits (725), Expect = 6e-77, Method: Composition-based stats. Identities = 81/332 (24%), Positives = 148/332 (44%), Gaps = 22/332 (6%) Query: 9 VFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLSDHVDKRIL 68 V+ T++ + + + E+E +D + ++ + G + ++D + +L Sbjct: 5 VYSTKQYDKKYLQQVNESFGFELEFFDF---LLTEKTAKTANGCEAVCIFVNDDGSRPVL 61 Query: 69 DAAGA-NLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLP 127 + +K I+ G +++ LD K+ G++V P + AE A+ +++T RR+ Sbjct: 62 EELKKHGVKYIALRCAGFNNVDLDAAKELGLKVVRVPAYDPEAVAEHAIGMMMTLNRRIH 121 Query: 128 EAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQP 187 A + ++ ++ L G+ + T G+IG G+IG A+ R LK FG++ + Sbjct: 122 RAYQRTRDANFSLE---GLTGFTMYGKTAGVIGTGKIGVAMLRILKGFGMRLLAFDPYP- 177 Query: 188 RPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGD 247 A E E+V P L ++SD I + C LTP L N+ F +MK + +N SRG Sbjct: 178 -SAAALELGVEYVDLPTLFSESDVISLHCPLTPENYHLLNEAAFDQMKNGVMIVNTSRGA 236 Query: 248 VVNQDDLYQALASGKIAAAGLDVTSPE----------PLPTNHPLLTLK---NCVILPHI 294 +++ +AL + KI + G+DV E + + L N + H Sbjct: 237 LIDSQAAIEALKNQKIGSLGMDVYENERDLFFEDKSNDVIQDDVFRRLSACHNVLFTGHQ 296 Query: 295 GSATHRTRNTMSLLAANNLLAGLRGEPMPSEL 326 T ++S NL +GE P+EL Sbjct: 297 AFLTAEALTSISQTTLQNLSNLEKGETCPNEL 328 >6ABJ-A nrPDB Length = 345 Score = 283 bits (723), Expect = 1e-76, Method: Composition-based stats. Identities = 79/288 (27%), Positives = 125/288 (43%), Gaps = 19/288 (6%) Query: 48 GVAGAHGLLCLLSDHVDKRILDA-AGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDV 106 G + ++D + + +L+ A ++++ S G +H+ L + G+ V + P Sbjct: 57 LAQGFEVVCAFVNDDLSRPVLERLAAGGTRLVALRSAGYNHVDLAAAEALGLPVVHVPAY 116 Query: 107 LTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQ 166 AE AV L+LT RRL A + G ++ L G+ L VG+IG G+IG+ Sbjct: 117 SPHAVAEHAVGLILTLNRRLHRAYNRTREGDFSLH---GLTGFDLHGKRVGVIGTGQIGE 173 Query: 167 AIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLC 226 AR + FG + Y +A +++ L A+SD + + C LT T L Sbjct: 174 TFARIMAGFGCELLAYDPYPNPRIQA--LGGRYLALDALLAESDIVSLHCPLTADTRHLI 231 Query: 227 NKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPE-----------P 275 + MK A+ IN RG +VN L +AL SG++ GLDV E P Sbjct: 232 DAQRLATMKPGAMLINTGRGALVNAAALIEALKSGQLGYLGLDVYEEEADIFFEDRSDQP 291 Query: 276 LPTN--HPLLTLKNCVILPHIGSATHRTRNTMSLLAANNLLAGLRGEP 321 L + LL+ N V+ H T ++ +N+ A G P Sbjct: 292 LQDDVLARLLSFPNVVVTAHQAFLTREALAAIADTTLDNIAAWQDGTP 339 >4CUK-A nrPDB Length = 338 Score = 280 bits (717), Expect = 4e-76, Method: Composition-based stats. Identities = 81/332 (24%), Positives = 144/332 (43%), Gaps = 22/332 (6%) Query: 9 VFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLSDHVDKRIL 68 V+ T++ + + A E+E +D + ++ + G + ++D + +L Sbjct: 5 VYSTKQYDKKYLQQVNEAFGFELEFFDF---LLTEKTAKTANGCEAVCIFVNDDGSRPVL 61 Query: 69 DAAGA-NLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLP 127 + +K I+ G +++ LD K+ G++V P + AE A+ +++T RR+ Sbjct: 62 EELKKHGVKYIALRCAGFNNVDLDAAKELGLQVVRVPAYSPEAVAEHAIGMMMTLNRRIH 121 Query: 128 EAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQP 187 A + ++ ++ L G+ + T G+IG G+IG A R LK FG++ + Sbjct: 122 RAYQRTRDANFSLE---GLTGFTMHGKTAGVIGTGKIGVAALRILKGFGMRLLAFDPYP- 177 Query: 188 RPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGD 247 A + E+V L A+SD I + C LTP L N F +MK + IN SRG Sbjct: 178 -STAALDLGVEYVDLQTLFAESDVISLHCPLTPENYHLLNHAAFDQMKNGVMIINTSRGA 236 Query: 248 VVNQDDLYQALASGKIAAAGLDVTSPE----------PLPTNHPLLTLK---NCVILPHI 294 +++ +AL + KI + G+DV E + + L N + H Sbjct: 237 LIDSQAAIEALKNQKIGSLGMDVYENERDLFFEDKSVDVIQDDVFRRLSACHNVLFTGHQ 296 Query: 295 GSATHRTRNTMSLLAANNLLAGLRGEPMPSEL 326 T ++S NL +GE P+ L Sbjct: 297 AFLTAEALISISETTLQNLSQLEKGEACPNAL 328 >3JTM-A nrPDB Length = 351 Score = 279 bits (713), Expect = 1e-75, Method: Composition-based stats. Identities = 81/296 (27%), Positives = 128/296 (43%), Gaps = 5/296 (1%) Query: 33 QWDSDEPIPAKELERGVAGAHGLL--CLLSDHVDKRILDAAGANLKVISTMSVGIDHLAL 90 D+ P ELE+ + H L+ +V + A K++ T +G DH+ L Sbjct: 44 IVTDDKEGPDCELEKHIPDLHVLISTPFHPAYVTAERIKKAKNL-KLLLTAGIGSDHIDL 102 Query: 91 DEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYG 150 G+ V + AE + +L R +V G W + Y Sbjct: 103 QAAAAAGLTVAEVTGSNVVSVAEDELMRILILMRNFVPGYNQVVKGEWNV-AGIAYRAYD 161 Query: 151 LTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFV-STPELAAQS 209 L T+G +G GRIG+ + +RLKPFG + Q PE E A+FV E+ + Sbjct: 162 LEGKTIGTVGAGRIGKLLLQRLKPFGCNLLYHDRLQMAPELEKETGAKFVEDLNEMLPKC 221 Query: 210 DFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLD 269 D IV+ LT T G+ NK+ K+K+ + +N +RG ++ + + A+ SG I D Sbjct: 222 DVIVINMPLTEKTRGMFNKELIGKLKKGVLIVNNARGAIMERQAVVDAVESGHIGGYSGD 281 Query: 270 VTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTMSLLAANNLLAGLRGEPMPSE 325 V P+P P +HP + N + PH T + + + L +GE P+E Sbjct: 282 VWDPQPAPKDHPWRYMPNQAMTPHTSGTTIDAQLRYAAGTKDMLERYFKGEDFPTE 337 >1HL3-A nrPDB Length = 358 Score = 277 bits (708), Expect = 6e-75, Method: Composition-based stats. Identities = 83/328 (25%), Positives = 131/328 (39%), Gaps = 16/328 (4%) Query: 14 RIPAEGRVALARAADCEVE---------QWDSDEPIPAKELERGVAGAHGLLCLLSDHVD 64 + VAL DC VE D + E+ + A G L + + Sbjct: 20 PMHPRPLVALLDGRDCTVEMPILKDVATVAFCDAQSTQEIHEKVLNEAVGALMYHTITLT 79 Query: 65 KRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCR 124 + L+ L++I + G D++ + GI V P + TA+ + +L R Sbjct: 80 REDLE-KFKALRIIVRIGSGFDNIDIKSAGDLGIAVCNVPAASVEETADSTLCHILNLYR 138 Query: 125 RLPEAIEEVKNGGW----TSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRF 180 R + ++ G + + + T+GIIGLGR+GQA+A R K FG Sbjct: 139 RTTWLHQALREGTRVQSVEQIREVASGAARIRGETLGIIGLGRVGQAVALRAKAFGFNVL 198 Query: 181 LYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVF 240 Y E A + +L SD + + C L L N ++M++ A Sbjct: 199 FYDPYLSDGIERALGLQRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFL 258 Query: 241 INISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNH-PLLTLKNCVILPHIGSATH 299 +N +RG +V++ L QAL G+I A LDV EP + PL N + PH + Sbjct: 259 VNTARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWYSE 318 Query: 300 RTRNTMSLLAANNLLAGLRGEPMPSELK 327 + M AA + + G +P LK Sbjct: 319 QASIEMREEAAREIRRAITGR-IPDSLK 345 >3DC2-A nrPDB Length = 529 Score = 277 bits (708), Expect = 6e-75, Method: Composition-based stats. Identities = 102/325 (31%), Positives = 158/325 (48%), Gaps = 11/325 (3%) Query: 4 VRLMKVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLSDHV 63 V L V + ++ AL EV D + +L V A LL + V Sbjct: 2 VSLPVVLIADKLAPSTVAAL--GDQVEVRWVDGPD---RDKLLAAVPEADALLVRSATTV 56 Query: 64 DKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTC 123 D +L AA LK+++ VG+D++ +D RG+ V P + AE A++LLL Sbjct: 57 DAEVL-AAAPKLKIVARAGVGLDNVDVDAATARGVLVVNAPTSNIHSAAEHALALLLAAS 115 Query: 124 RRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYT 183 R++P A ++ W G + TVG++GLGRIGQ +A+R+ FG Y Sbjct: 116 RQIPAADASLREHTWKRSS---FSGTEIFGKTVGVVGLGRIGQLVAQRIAAFGAYVVAYD 172 Query: 184 GRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINI 243 P AA+ E +S +L A++DFI V TP T GL +K+ K K + +N Sbjct: 173 PY-VSPARAAQLGIELLSLDDLLARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNA 231 Query: 244 SRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRN 303 +RG +V++ L A+ G + AAGLDV + EP T+ PL L V+ PH+G++T ++ Sbjct: 232 ARGGLVDEAALADAITGGHVRAAGLDVFATEPC-TDSPLFELAQVVVTPHLGASTAEAQD 290 Query: 304 TMSLLAANNLLAGLRGEPMPSELKL 328 A ++ L GE +P + + Sbjct: 291 RAGTDVAESVRLALAGEFVPDAVNV 315 >2OME-A nrPDB Length = 336 Score = 276 bits (707), Expect = 7e-75, Method: Composition-based stats. Identities = 79/324 (24%), Positives = 128/324 (39%), Gaps = 15/324 (4%) Query: 15 IPAEGRVALARAADCEVE---------QWDSDEPIPAKELERGVAGAHGLLCLLSDHVDK 65 + VAL DC VE D + E+ + A G + + + + Sbjct: 2 MHPRPLVALLDGRDCTVEMPILKDLATVAFCDAQSTQEIHEKVLNEAVGAMMYHTITLTR 61 Query: 66 RILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRR 125 L+ L+VI + G D++ + + GI V P + TA+ + +L RR Sbjct: 62 EDLE-KFKALRVIVRIGSGYDNVDIKAAGELGIAVCNIPSAAVEETADSTICHILNLYRR 120 Query: 126 LPEAIEEVKNGGW----TSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFL 181 + ++ G + + + T+G+IG GR GQA+A R K FG Sbjct: 121 NTWLYQALREGTRVQSVEQIREVASGAARIRGETLGLIGFGRTGQAVAVRAKAFGFSVIF 180 Query: 182 YTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFI 241 Y E + + +L QSD + + C+L L N ++M++ A + Sbjct: 181 YDPYLQDGIERSLGVQRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLV 240 Query: 242 NISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNH-PLLTLKNCVILPHIGSATHR 300 N +RG +V++ L QAL G+I A LDV EP PL N + PH + + Sbjct: 241 NAARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFAQGPLKDAPNLICTPHTAWYSEQ 300 Query: 301 TRNTMSLLAANNLLAGLRGEPMPS 324 M AA + + G S Sbjct: 301 ASLEMREAAATEIRRAITGRIPES 324 >6ABI-A nrPDB Length = 358 Score = 273 bits (698), Expect = 7e-74, Method: Composition-based stats. Identities = 80/298 (26%), Positives = 139/298 (46%), Gaps = 19/298 (6%) Query: 43 KELERGVAGAHGLLCLLSDHVDKRILDAAGAN-LKVISTMSVGIDHLALDEIKKRGIRVG 101 +E G + +D+++K +D N +K+++ G ++++L ++ +R +V Sbjct: 62 EETANLTKGYDVVCGFANDNINKETIDIMAENGIKLLAMRCAGFNNVSLKDVNER-FKVV 120 Query: 102 YTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGL 161 P AE V L+L R++ +A + G ++ L G L + T GIIG Sbjct: 121 RVPAYSPHAIAEYTVGLILAVNRKINKAYVRTREGNFSIN---GLMGIDLYEKTAGIIGT 177 Query: 162 GRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPA 221 G+IGQ + + L+ F ++ Y P + A E E+VS EL A SD I + C LT Sbjct: 178 GKIGQILIKILRGFDMKVIAYD-LFPNQKVADELGFEYVSLDELYANSDIISLNCPLTKD 236 Query: 222 TEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVT---------- 271 T+ + N+ KMK+ + +N RG +++ DL +AL KI A LDV Sbjct: 237 TKYMINRRSMLKMKDGVILVNTGRGMLIDSADLVEALKDKKIGAVALDVYEEEENYFFED 296 Query: 272 -SPEPLPTN--HPLLTLKNCVILPHIGSATHRTRNTMSLLAANNLLAGLRGEPMPSEL 326 S + + + LL+ N +I H T +++ NN+ + G P+ +E+ Sbjct: 297 KSTQVIEDDILGRLLSFYNVLITSHQAYFTKEAVGAITVTTLNNIKDFVEGRPLVNEV 354 >2PA3-A nrPDB Length = 410 Score = 273 bits (698), Expect = 8e-74, Method: Composition-based stats. Identities = 82/313 (26%), Positives = 130/313 (41%), Gaps = 13/313 (4%) Query: 8 KVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLSDHVDKRI 67 K + + + +L A +E + ++L+ + AH + H+ + + Sbjct: 12 KFLLVEGVHQKALESLRAAGYTNIEFHKGA--LDDEQLKESIRDAHFIGLRSRTHLTEDV 69 Query: 68 LDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLP 127 ++AA L I ++G + + LD KRGI V P T + AEL + LL R +P Sbjct: 70 INAA-EKLVAIGAFAIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVP 128 Query: 128 EAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQP 187 EA + G W L + +GIIG G IG + + G+ + Y Sbjct: 129 EANAKAHRGVWNK---LAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENK 185 Query: 188 RPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGD 247 P A + +L SD + + P+T+ + MK ++ IN SRG Sbjct: 186 LPLGNAT---QVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGT 242 Query: 248 VVNQDDLYQALASGKIAAAGLDVTSPEPL----PTNHPLLTLKNCVILPHIGSATHRTRN 303 VV+ L ALAS +A A +DV EP P PL N ++ PHIG +T + Sbjct: 243 VVDIPALADALASKHLAGAAIDVFPTEPATNSDPFTSPLAEFDNVLLTPHIGGSTQEAQE 302 Query: 304 TMSLLAANNLLAG 316 + L A L+ Sbjct: 303 NIGLEVAGKLIKY 315 >2EKL-A nrPDB Length = 313 Score = 271 bits (692), Expect = 4e-73, Method: Composition-based stats. Identities = 80/313 (25%), Positives = 139/313 (44%), Gaps = 13/313 (4%) Query: 8 KVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLSDHVDKRI 67 K +T I L Q D I +EL + ++ V K + Sbjct: 7 KALITDPIDEILIKTLREKG----IQVDYMPEISKEELLNIIGNYDIIVVRSRTKVTKDV 62 Query: 68 LDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLP 127 ++ G LK+I+ +G+D++ +E +KR I+V Y P TD+ EL + L++ R++ Sbjct: 63 IE-KGKKLKIIARAGIGLDNIDTEEAEKRNIKVVYAPGASTDSAVELTIGLMIAAARKMY 121 Query: 128 EAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQP 187 ++ K+G + + G L T+GI+G GRIG + G++ Y Sbjct: 122 TSMALAKSGIFKKIE-----GLELAGKTIGIVGFGRIGTKVGIIANAMGMKVLAYDILDI 176 Query: 188 RPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGD 247 R E+A + A+ VS EL SD I + +++ + + + F+ MK+ + +N SR Sbjct: 177 R-EKAEKINAKAVSLEELLKNSDVISLHVTVSKDAKPIIDYPQFELMKDNVIIVNTSRAV 235 Query: 248 VVNQDDLYQALASGKIAAAGLDVTSPEPLPTNH--PLLTLKNCVILPHIGSATHRTRNTM 305 VN L + GK+ A DV EP LL + ++ HIG+ T + + Sbjct: 236 AVNGKALLDYIKKGKVYAYATDVFWNEPPKEEWELELLKHERVIVTTHIGAQTKEAQKRV 295 Query: 306 SLLAANNLLAGLR 318 + + NLL ++ Sbjct: 296 AEMTTQNLLNAMK 308 >1DXY-A nrPDB Length = 333 Score = 270 bits (691), Expect = 5e-73, Method: Composition-based stats. Identities = 73/297 (24%), Positives = 123/297 (41%), Gaps = 20/297 (6%) Query: 39 PIPAKELERGVAGAHGLLCLLSDHVDKRILDAA-GANLKVISTMSVGIDHLALDEIKKRG 97 + G G+ L + + + +K ++ +VG D++ + +K+ G Sbjct: 32 EFLDENTVEWAKGFDGINSLQTTPYAAGVFEKMHAYGIKFLTIRNVGTDNIDMTAMKQYG 91 Query: 98 IRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVG 157 IR+ P AE A++ L R + + +++ G + K G L Q TVG Sbjct: 92 IRLSNVPAYSPAAIAEFALTDTLYLLRNMGKVQAQLQAGDYE--KAGTFIGKELGQQTVG 149 Query: 158 IIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACS 217 ++G G IGQ + K FG + Y P P + ++VS +L QSD I + Sbjct: 150 VMGTGHIGQVAIKLFKGFGAKVIAYD---PYPMKGDHPDFDYVSLEDLFKQSDVIDLHVP 206 Query: 218 LTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPL- 276 + N+ F MK A+ IN +R ++++ + L SGK+A G+D E Sbjct: 207 GIEQNTHIINEAAFNLMKPGAIVINTARPNLIDTQAMLSNLKSGKLAGVGIDTYEYETED 266 Query: 277 ------------PTNHPLLTLKNCVILPHIGSATHRTRNTMSLLAANNLLAGL-RGE 320 P LL + N V+ PHI T + M + +L+ L +GE Sbjct: 267 LLNLAKHGSFKDPLWDELLGMPNVVLSPHIAYYTETAVHNMVYFSLQHLVDFLTKGE 323 >3K5P-A nrPDB Length = 416 Score = 269 bits (689), Expect = 1e-72, Method: Composition-based stats. Identities = 73/312 (23%), Positives = 122/312 (39%), Gaps = 13/312 (4%) Query: 9 VFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLSDHVDKRIL 68 V + I + + + +L + ++ AH + + + I Sbjct: 18 VLLLEGISQTAVEYFKSSG--YTNVTHLPKALDKADLIKAISSAHIIGIRSRTQLTEEIF 75 Query: 69 DAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPE 128 AA L + SVG + + L +KRGI V P T + AEL + ++ RR+ Sbjct: 76 -AAANRLIAVGCFSVGTNQVELKAARKRGIPVFNAPFSNTRSVAELVIGEIIMLMRRIFP 134 Query: 129 AIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPR 188 GGW + + + T+GI+G G IG + + G+ Y Sbjct: 135 RSVSAHAGGW---EKTAIGSREVRGKTLGIVGYGNIGSQVGNLAESLGMTVRYYDTSDKL 191 Query: 189 PEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDV 248 + A S EL SD + + + +T L + +KMK+ A IN +RG Sbjct: 192 QYGNVKPAA---SLDELLKTSDVVSLHVPSSKSTSKLITEAKLRKMKKGAFLINNARGSD 248 Query: 249 VNQDDLYQALASGKIAAAGLDVTSPEPLPTNH----PLLTLKNCVILPHIGSATHRTRNT 304 V+ + L + L G +A A +DV EP PL L+N ++ PHIG +T + Sbjct: 249 VDLEALAKVLQEGHLAGAAIDVFPVEPASNGERFSTPLQGLENVILTPHIGGSTEEAQER 308 Query: 305 MSLLAANNLLAG 316 + L+ Sbjct: 309 IGTEVTRKLVEY 320 >1J49-A nrPDB Length = 333 Score = 267 bits (683), Expect = 4e-72, Method: Composition-based stats. Identities = 74/316 (23%), Positives = 135/316 (42%), Gaps = 20/316 (6%) Query: 27 ADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLS-DHVDKRILDAAGANLKVISTMSVGI 85 A +VE +D+ + + + GA G++ D++ + + A + +S +VG+ Sbjct: 23 AHKDVEVEYTDKLLTPETV-ALAKGADGVVVYQQLDYIAETLQALADNGITKMSLRNVGV 81 Query: 86 DHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLW 145 D++ + + K+ G ++ P + AE A R+ +A++E W P Sbjct: 82 DNIDMAKAKELGFQITNVPVYSPNAIAEHAAIQAARILRQ-DKAMDEKVARHDLRWAPT- 139 Query: 146 LCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPEL 205 G + VG++G G IGQ + ++ FG + Y + E + + S +L Sbjct: 140 -IGREVRDQVVGVVGTGHIGQVFMQIMEGFGAKVITYDIFRNPELEKKGYYVD--SLDDL 196 Query: 206 AAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAA 265 Q+D I + PA + N + KMK+ V +N+SRG +V+ D + + L SGKI Sbjct: 197 YKQADVISLHVPDVPANVHMINDESIAKMKQDVVIVNVSRGPLVDTDAVIRGLDSGKIFG 256 Query: 266 AGLDVTSPE-------------PLPTNHPLLTLKNCVILPHIGSATHRTRNTMSLLAANN 312 +DV E P L+ N ++ PH T M + A +N Sbjct: 257 YAMDVYEGEVGIFNEDWEGKEFPDARLADLIARPNVLVTPHTAFYTTHAVRNMVVKAFDN 316 Query: 313 LLAGLRGEPMPSELKL 328 L + G+ + +K+ Sbjct: 317 NLELVEGKEAETPVKV 332 >2DLD-A nrPDB Length = 337 Score = 266 bits (679), Expect = 1e-71, Method: Composition-based stats. Identities = 76/318 (23%), Positives = 130/318 (40%), Gaps = 20/318 (6%) Query: 25 RAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLS-DHVDKRILDAAGANLKVISTMSV 83 + A +++ +D+ + E + GA G++ D+ + A A + +S +V Sbjct: 21 KEAHKDIDVDYTDKLLTP-ETAKLAKGADGVVVYQQLDYTADTLQALADAGVTKMSLRNV 79 Query: 84 GIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKP 143 G+D++ +D+ K+ G ++ P + AE A R+ E++ W P Sbjct: 80 GVDNIDMDKAKELGFQITNVPVYSPNAIAEHAAIQAARVLRQDKRMDEKMAKRD-LRWAP 138 Query: 144 LWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTP 203 G + VG++G G IGQ R ++ FG + Y + E + + S Sbjct: 139 T--IGREVRDQVVGVVGTGHIGQVFMRIMEGFGAKVIAYDIFKNPELEKKGYYVD--SLD 194 Query: 204 ELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKI 263 +L Q+D I + PA + N +MK+ V +N SRG +V+ D + + L SGKI Sbjct: 195 DLYKQADVISLHVPDVPANVHMINDKSIAEMKDGVVIVNCSRGRLVDTDAVIRGLDSGKI 254 Query: 264 AAAGLDVTSPE-------------PLPTNHPLLTLKNCVILPHIGSATHRTRNTMSLLAA 310 +D E P L+ N ++ PH T M + A Sbjct: 255 FGFVMDTYEDEVGVFNKDWEGKEFPDKRLADLIDRPNVLVTPHTAFYTTHAVRNMVVKAF 314 Query: 311 NNLLAGLRGEPMPSELKL 328 NN L + GE S + L Sbjct: 315 NNNLKLINGEKPDSPVAL 332 >4PRK-A nrPDB Length = 336 Score = 265 bits (678), Expect = 2e-71, Method: Composition-based stats. Identities = 83/323 (25%), Positives = 141/323 (43%), Gaps = 26/323 (8%) Query: 16 PAEGRVALARAAD----CEVEQWDSDEPIPAKELERGVAGAHGLLCLLSDHVDKRIL--D 69 P+E L A + CE++ DE + A+ +++ VA G+L ++D I+ Sbjct: 8 PSESERKLVAATEKKFGCELKLI--DESLSAENVDQ-VADCDGVLLKPLGNLDDEIVYKK 64 Query: 70 AAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEA 129 A +K I VG + + D KK + V P AE+AV+ + R++ E Sbjct: 65 LADYGIKSIGLRIVGTNTIDFDLAKKYHLTVTNVPVYSPRAIAEMAVTQAMYLNRKIGEF 124 Query: 130 IEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRP 189 + G +T P L + T+G+IG+G IG A+A+ G + Y Sbjct: 125 KANMDKGDFT--NPDSLISNEIYNKTIGLIGVGHIGSAVAQIFSAMGAKVLAYDVIY--- 179 Query: 190 EEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVV 249 E + + ++D I + L +TE + K F +MK A+ IN +RG++V Sbjct: 180 NPEVEPYLTYADFDTVLKEADIISLHTPLLKSTENMIGKKQFAEMKNDAILINAARGELV 239 Query: 250 NQDDLYQALASGKIAAAGLDVTSPEP-----------LPTNH-PLLTLKNCVILPHIGSA 297 + L +AL +IAAAGLD + E +P ++ L + N ++ PH Sbjct: 240 DTAALIEALEKHEIAAAGLDTLAHESSYFFKKVDDAQIPADYKKLAAMPNVIVTPHSAYF 299 Query: 298 THRTRNTMSLLAANNLLAGLRGE 320 T + M ++ + +A GE Sbjct: 300 TKTSVRNMIEISLRDTIALANGE 322 >6D4C-A nrPDB Length = 364 Score = 264 bits (675), Expect = 4e-71, Method: Composition-based stats. Identities = 82/299 (27%), Positives = 130/299 (43%), Gaps = 13/299 (4%) Query: 33 QWDSDEPIPAKELERGVAGAHGLLCLL--SDHVDKRILDAAGANLKVISTMSVGIDHLAL 90 SD+ L++ + A ++ ++ K +D A LK++ VG DH+ L Sbjct: 42 ITTSDKEGGNSVLDQHIPDADIIITTPFHPAYITKERIDKA-KKLKLVVVAGVGSDHIDL 100 Query: 91 DEIKKRG--IRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCG 148 D I + G I V + AE + +L R A E++ N W + Sbjct: 101 DYINQTGKKISVLEVTGSNVVSGAEHVLMTMLVLVRNFVPAHEQIINHDWEV-AAIAKDA 159 Query: 149 YGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQA--EFVSTPELA 206 Y + T+ IG GRIG + RL PF + LY Q P++A E + EL Sbjct: 160 YDIEGKTIATIGAGRIGYRVLERLVPFNPKELLYYDYQALPKDAEEKVGARRVENIEELV 219 Query: 207 AQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAA 266 AQ+D + + L T+GL NK+ K K+ A +N +RG + +D+ AL SG++ Sbjct: 220 AQADIVTINAPLHAGTKGLINKELLSKFKKGAWLVNTARGAICVAEDVAAALESGQLRGY 279 Query: 267 GLDVTSPEPLPTNHPLLTLKN-----CVILPHIGSATHRTRNTMSLLAANNLLAGLRGE 320 G DV P+P P +HP ++N + PH T + + N L + G+ Sbjct: 280 GGDVWFPQPAPKDHPWRDMRNKYGAGNAMTPHYSGTTLDAQTRYAEGTKNILESFFTGK 338 >4XYG-A nrPDB Length = 391 Score = 262 bits (670), Expect = 1e-70, Method: Composition-based stats. Identities = 82/297 (27%), Positives = 129/297 (43%), Gaps = 7/297 (2%) Query: 33 QWDSDEPIPAKELERGVAGAHGLL--CLLSDHVDKRILDAAGANLKVISTMSVGIDHLAL 90 SD+ P E+ + A ++ ++ + A K+ T +G DH+ L Sbjct: 72 IVTSDKEGPNSVFEKELPDADIVISQPFWPAYLTAERIAKAKKL-KLALTAGIGSDHVDL 130 Query: 91 DEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYG 150 + K GI V AE AV ++L R + + + GGW + Y Sbjct: 131 NAAIKAGITVAEETFSNGICVAEHAVMMILALVRNYLPSHKIAEEGGWNIADCVS-RSYD 189 Query: 151 LTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEE-AAEFQAEFVST-PELAAQ 208 L VG + GRIG A+ RRLKPF V+ YT R P E + +T E+A Sbjct: 190 LEGMHVGTVAAGRIGLAVLRRLKPFDVK-LHYTARHRSPRAIEDELGLTYHATAEEMAEV 248 Query: 209 SDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGL 268 D I + L PATE L N KM+ + +N +R ++ ++DD+ +AL SG++A Sbjct: 249 CDVISIHAPLYPATEHLFNAKVLNKMRHGSYLVNTARAEICDRDDIVRALESGQLAGYAG 308 Query: 269 DVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTMSLLAANNLLAGLRGEPMPSE 325 DV P+P P NHP + + + PH+ ++ + + L P+ E Sbjct: 309 DVWFPQPAPANHPWRNMPHNGMTPHMSGSSLSGQARYAAGTREILECWFENRPIRDE 365 >3HG7-A nrPDB Length = 324 Score = 261 bits (668), Expect = 2e-70, Method: Composition-based stats. Identities = 80/315 (25%), Positives = 133/315 (42%), Gaps = 17/315 (5%) Query: 14 RIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLSDHVDKRILDAAGA 73 E + A + + D+ + E+ + AH L+++ + L A Sbjct: 15 NAHYERLLKAAHLPHLRILRADNQS-----DAEKLIGEAH---ILMAEPARAKPLLAKAN 66 Query: 74 NLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEV 133 L + G+D L LD +R ++ + +E LL+ R+LP E+ Sbjct: 67 KLSWFQSTYAGVDVL-LDARCRRDYQLTNVRGIFGPLMSEYVFGHLLSLMRQLPLYREQQ 125 Query: 134 KNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAA 193 K W S GL T+ I+G G IGQ IA K FG++ R R Sbjct: 126 KQRLWQSHP-----YQGLKGRTLLILGTGSIGQHIAHTGKHFGMKVLG-VSRSGRERAGF 179 Query: 194 EFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDD 253 + + + ++ AQ+D IV T T L F+ K A+ N+ RG+ +N+ D Sbjct: 180 DQVYQLPALNKMLAQADVIVSVLPATRETHHLFTASRFEHCKPGAILFNVGRGNAINEGD 239 Query: 254 LYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTMSLLAANNL 313 L AL +GK+ A LDV EPLP + PL N +I PH + + + ++ + N Sbjct: 240 LLTALRTGKLGMAVLDVFEQEPLPADSPLWGQPNLIITPHNSAYSF--PDDVAQIFVRNY 297 Query: 314 LAGLRGEPMPSELKL 328 + + G+P+ ++ Sbjct: 298 IRFIDGQPLDGKIDF 312 >4DGS-A nrPDB Length = 340 Score = 255 bits (652), Expect = 2e-68, Method: Composition-based stats. Identities = 86/258 (33%), Positives = 132/258 (51%), Gaps = 6/258 (2%) Query: 70 AAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEA 129 +L +I+ VG D + L ++R I V TP VL D A+L ++L+L RR+ + Sbjct: 89 EKLPSLGIIAINGVGTDKVDLARARRRNIDVTTTPGVLADDVADLGIALMLAVLRRVGDG 148 Query: 130 IEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRP 189 V+ G W + + L L G+ +G++GLG+IG+A+A R + FG+ + R Sbjct: 149 DRLVREGRWAAGEQLPL-GHSPKGKRIGVLGLGQIGRALASRAEAFGMSVRYWN----RS 203 Query: 190 EEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVV 249 + S +LA SD + V + + AT+ + + Q + + +N++RG+VV Sbjct: 204 TLSGVDWIAHQSPVDLARDSDVLAVCVAASAATQNIVDASLLQALGPEGIVVNVARGNVV 263 Query: 250 NQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTMSLLA 309 ++D L +AL SG IA AGLDV EP T N V++PH GSAT TR M L Sbjct: 264 DEDALIEALKSGTIAGAGLDVFVNEPAIR-SEFHTTPNTVLMPHQGSATVETRMAMGKLV 322 Query: 310 ANNLLAGLRGEPMPSELK 327 NL A GE P+ + Sbjct: 323 LANLAAHFAGEKAPNTVN 340 >1XDW-A nrPDB Length = 331 Score = 255 bits (651), Expect = 2e-68, Method: Composition-based stats. Identities = 72/303 (23%), Positives = 122/303 (40%), Gaps = 20/303 (6%) Query: 40 IPAKELERGVAGAHGLLCLLSDHVDKRILDAAGA-NLKVISTMSVGIDHLALDEIKKRGI 98 + KE AG ++ + +K+ LD +K I T + G DH+ + K+ G Sbjct: 34 LNTKETAEMAAGFDAVILRGNCFANKQNLDIYKKLGVKYILTRTAGTDHIDKEYAKELGF 93 Query: 99 RVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGI 158 + + P + AELAV+ + R + ++ + TVG+ Sbjct: 94 PMAFVPRYSPNAIAELAVTQAMMLLRHTAYTTSRTAKKNFKVDA--FMFSKEVRNCTVGV 151 Query: 159 IGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSL 218 +GLGRIG+ A+ G + E VS E+ +SD I + Sbjct: 152 VGLGRIGRVAAQIFHGMGATVIG---EDVFEIKGIEDYCTQVSLDEVLEKSDIITIHAPY 208 Query: 219 TPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPL-- 276 + +DF +KMK+ A+ +N +RG +V+ + + +A+ SGK+ G DV E Sbjct: 209 IKENGAVVTRDFLKKMKDGAILVNCARGQLVDTEAVIEAVESGKLGGYGCDVLDGEASVF 268 Query: 277 -----------PTNHPLLTL-KNCVILPHIGSATHRTRNTMSLLAANNLLAGLRGEPMPS 324 P L+ L +I PH+GS T M ++ NL P+ Sbjct: 269 GKDLEGQKLENPLFEKLVDLYPRVLITPHLGSYTDEAVKNMVEVSYQNLKDLAETGDCPN 328 Query: 325 ELK 327 ++K Sbjct: 329 KIK 331 >3GG9-A nrPDB Length = 352 Score = 254 bits (650), Expect = 3e-68, Method: Composition-based stats. Identities = 81/289 (28%), Positives = 129/289 (44%), Gaps = 16/289 (5%) Query: 44 ELERGVAGAHGLL-CLLSDHVDKRILDAAGANLKVISTMS-----VGIDHLALDEIKKRG 97 +L VA L+ V +++LD LK+IS G H+ L+ +G Sbjct: 41 QLAARVADVEALVLIRERTRVTRQLLDRL-PKLKIISQTGRVSRDAG-GHIDLEACTDKG 98 Query: 98 IRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTS-------WKPLWLCGYG 150 + V AEL +L++ RR+P+ + +K+G W P + G Sbjct: 99 VVVLEGKG-SPVAPAELTWALVMAAQRRIPQYVASLKHGAWQQSGLKSTTMPPNFGIGRV 157 Query: 151 LTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSD 210 L T+GI G G+IGQ +A + FG+ ++ + A+ A S L QSD Sbjct: 158 LKGQTLGIFGYGKIGQLVAGYGRAFGMNVLVWGRENSKERARADGFAVAESKDALFEQSD 217 Query: 211 FIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDV 270 + V L T + +MK TA+F+N SR ++V ++ + AL G+ A +DV Sbjct: 218 VLSVHLRLNDETRSIITVADLTRMKPTALFVNTSRAELVEENGMVTALNRGRPGMAAIDV 277 Query: 271 TSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTMSLLAANNLLAGLRG 319 EP+ H LL ++NC+ PHIG + +A N+L L+G Sbjct: 278 FETEPILQGHTLLRMENCICTPHIGYVERESYEMYFGIAFQNILDILQG 326 >5OFW-B nrPDB Length = 223 Score = 254 bits (650), Expect = 3e-68, Method: Composition-based stats. Identities = 71/223 (31%), Positives = 120/223 (53%), Gaps = 5/223 (2%) Query: 100 VGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGII 159 V TP+ + + AEL +++ R++P+A +K+G W K G L T+GI+ Sbjct: 3 VMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWERKK---FMGTELNGKTLGIL 59 Query: 160 GLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLT 219 GLGRIG+ +A R++ FG++ Y PE +A F + + E+ DFI V L Sbjct: 60 GLGRIGREVATRMQSFGMKTIGYDPI-ISPEVSASFGVQQLPLEEIWPLCDFITVHTPLL 118 Query: 220 PATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTN 279 P+T GL N + F + K+ +N +RG +V++ L +AL SG+ A A LDV + EP P + Sbjct: 119 PSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEP-PRD 177 Query: 280 HPLLTLKNCVILPHIGSATHRTRNTMSLLAANNLLAGLRGEPM 322 L+ +N + PH+G++T ++ A + ++G+ + Sbjct: 178 RALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSL 220 >4LSW-A nrPDB Length = 318 Score = 254 bits (649), Expect = 4e-68, Method: Composition-based stats. Identities = 92/320 (28%), Positives = 143/320 (44%), Gaps = 9/320 (2%) Query: 7 MKVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLSDHVDKR 66 ++ PA + L A D + V + + R Sbjct: 4 PEILQLGPYPAWDQEPLDAAFTVHRLFEADD----RAAMLANVGDRIRAIATRGELGASR 59 Query: 67 ILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRL 126 L A NL++IS VG D + L ++RGI+V TPDVLT A+L V+++L R + Sbjct: 60 ALIEACPNLELISVYGVGYDAVDLAACRERGIQVTNTPDVLTGDVADLGVAMMLAQSRGI 119 Query: 127 PEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQ 186 A ++G W + + L+ + G++GLGRIG +ARRL F +Q Y+ Sbjct: 120 IGAETWARSGKWAA-EGLYPLKRRVFGRRAGVLGLGRIGFEVARRLAGFDMQ-ISYSDIA 177 Query: 187 PRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRG 246 P+ E T LA DF+ V + + AT + +D + + + INISR Sbjct: 178 PKSYAPDWTFVEDAVT--LARDVDFLFVTLAASAATRHIVGRDVIEALGPEGMLINISRA 235 Query: 247 DVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTMS 306 ++++ L ALA G++ +A LDV EP + L N ++ PH S T TR M Sbjct: 236 SNIDEEALIAALADGRLGSAALDVFEGEP-NFDPRFRDLPNVLLQPHHASGTIETRKAMG 294 Query: 307 LLAANNLLAGLRGEPMPSEL 326 L +NL A G P+ + + Sbjct: 295 QLLRDNLTAHFAGSPLLTPV 314 >2YQ5-A nrPDB Length = 343 Score = 251 bits (642), Expect = 3e-67, Method: Composition-based stats. Identities = 72/308 (23%), Positives = 124/308 (40%), Gaps = 21/308 (6%) Query: 30 EVEQWDSDEPIPAKELERGVAGAHGLLCLLSDHVDKRIL--DAAGANLKVISTMSVGIDH 87 +VE +D+ + + ++ G + VD+ ++ + +K I VG + Sbjct: 25 DVEIKTTDQALTSATVD-LAEGCSSVSLKPLGPVDEEVVYQKLSEYGVKCIGLRIVGFNT 83 Query: 88 LALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLC 147 + D KK + V P AE+ V+ + R++ E + + +W P L Sbjct: 84 INFDWTKKYNLLVTNVPVYSPRAIAEMTVTQAMYLLRKIGEFRYRMDHDHDFTW-PSNLI 142 Query: 148 GYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAA 207 + TVG+IG+G IG A+A G + Y E + + Sbjct: 143 SNEIYNLTVGLIGVGHIGSAVAEIFSAMGAKVIAYDVAY---NPEFEPFLTYTDFDTVLK 199 Query: 208 QSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAG 267 ++D + + L P+TE + + ++MK++A IN +RG++V+ L +AL G+IA AG Sbjct: 200 EADIVSLHTPLFPSTENMIGEKQLKEMKKSAYLINCARGELVDTGALIKALQDGEIAGAG 259 Query: 268 LDVTSPEPLPTNH-------------PLLTLKNCVILPHIGSATHRTRNTMSL-LAANNL 313 LD + E H L + N VI PH T + M + L Sbjct: 260 LDTLAGESSYFGHTGLTDSEIPEDYKTLAKMPNVVITPHSAFYTETSIRNMVQICLTDQL 319 Query: 314 LAGLRGEP 321 G P Sbjct: 320 TIAKGGRP 327 >3WNV-A nrPDB Length = 330 Score = 250 bits (639), Expect = 6e-67, Method: Composition-based stats. Identities = 94/318 (29%), Positives = 154/318 (48%), Gaps = 19/318 (5%) Query: 6 LMKVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLSDHVDK 65 L + + P GR +C+ Q+D I + G D+ Sbjct: 22 LSSLVTLKEFPEGGREKFLE--NCKSGQYDDVIAIYRSNISTKHTG----------PFDR 69 Query: 66 RILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRR 125 ++ A ++K I G D++ +D + GI + TP + + TA++A+ L++ R+ Sbjct: 70 ELISALPKSVKYICHNGAGYDNIDVDAATEAGIAISSTPIAVNNATADVAIFLMIGALRQ 129 Query: 126 LPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGR 185 I ++ G W L G+ T+GI+G+G IG+ +ARR + FG+ Y R Sbjct: 130 AYVPITAIRAGEWHGKTTL---GHDPNGKTLGILGMGGIGREVARRARAFGMNII-YHNR 185 Query: 186 QPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISR 245 P E A++VS EL AQSD + +L +T + + KMK+ V +N +R Sbjct: 186 NKLP-PELEDGAKYVSFDELLAQSDVFSLNLALNASTRHIIGEKELAKMKDGVVIVNTAR 244 Query: 246 GDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTM 305 G ++++ L +AL SGK+A+ GLDV EP LL ++LPHIG+ T+ T+ M Sbjct: 245 GALIDEKALVRALESGKVASVGLDVYENEP-QVEPGLLNNPRAMLLPHIGTMTYETQKEM 303 Query: 306 SLLAANNLLAGL-RGEPM 322 LL NNL + + +GE + Sbjct: 304 ELLVLNNLRSAIEKGELL 321 >2W2L-A nrPDB Length = 348 Score = 243 bits (620), Expect = 9e-65, Method: Composition-based stats. Identities = 75/269 (27%), Positives = 125/269 (46%), Gaps = 8/269 (2%) Query: 64 DKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTC 123 + ++ ++LKV + G D L LD + +RG+ + T++LA+ L+L+ Sbjct: 70 NADLISHLPSSLKVFAAAGAGFDWLDLDALNERGVAFANSRGAGDTATSDLALYLILSVF 129 Query: 124 RRLPEAIEEVKNGGWTSWKPLWL----CGYGLTQSTVGIIGLGRIGQAIARRL-KPFGVQ 178 R + + G ++ + L + +G +GLG I + IAR+ G++ Sbjct: 130 RLASYSERAARTGDPETFNRVHLEIGKSAHNPRGHVLGAVGLGAIQKEIARKAVHGLGMK 189 Query: 179 RFLYTGRQPRPEEAAEFQAEFV-STPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKET 237 Y E AE V S ELA +SD + V+ T L ++ FF MK Sbjct: 190 LVYYDVAPADAETEKALGAERVDSLEELARRSDCVSVSVPYMKLTHHLIDEAFFAAMKPG 249 Query: 238 AVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSA 297 + +N +RG V++QD L AL SGK+ +AGLDV EP + L+ +K+ + HIG Sbjct: 250 SRIVNTARGPVISQDALIAALKSGKLLSAGLDVHEFEP-QVSKELIEMKHVTLTTHIGGV 308 Query: 298 THRTRNTMSLLAANNLLAG-LRGEPMPSE 325 T + L N+ L+G+P+ + Sbjct: 309 AIETFHEFERLTMTNIDRFLLQGKPLLTP 337 >4S1V-D nrPDB Length = 332 Score = 240 bits (613), Expect = 6e-64, Method: Composition-based stats. Identities = 77/274 (28%), Positives = 120/274 (43%), Gaps = 5/274 (1%) Query: 45 LERGVAGAHGLL-CLLSDHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYT 103 L + L+ + + +L NLK+IS +H+ + ++ G+ V Sbjct: 41 LIERLKPFEALVLIRERTPITENLLAHL-PNLKLISQTGKVSNHIDVPLCERYGVTVLEG 99 Query: 104 PDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGR 163 AEL SL+L R LP IE++ G W L L G L+ T+GI GLG+ Sbjct: 100 IG-SPVAPAELCWSLILAASRHLPSYIEQLHAGHWQQNGGLGL-GRTLSGRTLGIWGLGK 157 Query: 164 IGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATE 223 IGQ IA+ FG+ ++ R + E A++D + + L AT Sbjct: 158 IGQRIAQFGHVFGMPILVWGSEASRQKALELGYQAAADKAEFFAKADVLSLHLRLNDATR 217 Query: 224 GLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEP-LPTNHPL 282 G+ K MK ++F+N SR ++V LY + + + A +DV EP LP N PL Sbjct: 218 GIVTKQDLLAMKPDSLFVNTSRAELVESGALYSVMQANPMRQAAVDVYENEPALPNNEPL 277 Query: 283 LTLKNCVILPHIGSATHRTRNTMSLLAANNLLAG 316 L+L N + PH+G + A N++ Sbjct: 278 LSLPNVLCAPHLGYVEKNSYEIYFQAAFENVVKF 311 >5UOG-A nrPDB Length = 344 Score = 235 bits (600), Expect = 2e-62, Method: Composition-based stats. Identities = 105/317 (33%), Positives = 146/317 (46%), Gaps = 14/317 (4%) Query: 7 MKVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLSDHVDKR 66 ++ V +I L + V +D + ++ G+ V Sbjct: 26 PRILVPGKINPRVLERLPEMFET-VRIERADAALVTADM----RDVSGIAVSGKLPV--- 77 Query: 67 ILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRL 126 L A +L++++ VG D + + RGI V TPDVLT+ A+ A+ LLL T R L Sbjct: 78 PLMDAFPSLEIVANFGVGYDGVDVSRAAARGIVVTNTPDVLTEEVADTAIGLLLNTLRLL 137 Query: 127 PEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQ 186 P+A + ++ G W L L TVG+ GLGRIG AIARRL+ FGV Y R Sbjct: 138 PQAEQWLRQGRWVREGAFPLSPLSLRGRTVGLFGLGRIGLAIARRLEAFGVS-IAYHTRT 196 Query: 187 PRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRG 246 PR + V +A D ++V T +T N D + V IN+ RG Sbjct: 197 PREGLGFTYHPTLVG---MAEAVDTLIVIVPGTASTLKAVNADVLSALGPKGVLINVGRG 253 Query: 247 DVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTMS 306 V++ L AL +G IA AGLDV EP LL+ N +LPH+ SA+ TRN MS Sbjct: 254 STVDEAALVTALQNGTIAGAGLDVFENEP-NVPEALLSFPNVSLLPHVASASVVTRNAMS 312 Query: 307 LLAANNLLAGL-RGEPM 322 L +NL A GE + Sbjct: 313 DLVVDNLKAWFSTGEAL 329 >5MH6-A nrPDB Length = 308 Score = 230 bits (587), Expect = 7e-61, Method: Composition-based stats. Identities = 68/250 (27%), Positives = 113/250 (45%), Gaps = 3/250 (1%) Query: 77 VISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNG 136 + + G D + ++ G + + + T E +LT RRL + + Sbjct: 61 WVHCIRAGYDEFPVGVYEEAGTYLTNSTGIHGTTVGETVAGYMLTFARRLHAYRDAQHDH 120 Query: 137 GWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQ 196 W P + + L V ++GLG +G+ + R G++ R P + Sbjct: 121 AWDL--PRYEEPFTLAGERVCVVGLGTLGRGVVDRAAALGMEVVG-VRRSGDPVDNVSTV 177 Query: 197 AEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQ 256 E A + F+V+A LT TEG+ F+ M+E A +N++RG VV + DL Sbjct: 178 YTPDRLHEAIADARFVVLATPLTDETEGMVAAPEFETMREDASLVNVARGPVVVESDLVA 237 Query: 257 ALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTMSLLAANNLLAG 316 AL SG IA A LDV S EPLP + PL ++ +I PH+ +AT + ++ L N+ Sbjct: 238 ALDSGDIAGAALDVFSEEPLPEDSPLWDFEDVLITPHVSAATSKYHEDVAALIRENIEKI 297 Query: 317 LRGEPMPSEL 326 G+ + + + Sbjct: 298 ATGDELTNRV 307 >3EVT-A nrPDB Length = 324 Score = 229 bits (585), Expect = 1e-60, Method: Composition-based stats. Identities = 81/283 (28%), Positives = 131/283 (46%), Gaps = 6/283 (2%) Query: 48 GVAGAHGL-LCLLSDHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDV 106 A + + + + K IL LK + +S G+D+L L ++ G+ V T + Sbjct: 34 TAADYDQIEVMYGNHPLLKTILARPTNQLKFVQVISAGVDYLPLKALQAAGVVVANTSGI 93 Query: 107 LTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQ 166 D +E ++ +L+ R A + G W L + LT + I G G+IGQ Sbjct: 94 HADAISESVLAAMLSVVRGYHAA--WLNQRGARQWA-LPMTTSTLTGQQLLIYGTGQIGQ 150 Query: 167 AIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLC 226 ++A + G+ P + F +T + A ++FIV A LTP T L Sbjct: 151 SLAAKASALGMHVIG-VNTTGHPADHFHETVAFTATADALATANFIVNALPLTPTTHHLF 209 Query: 227 NKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLK 286 + + FQ+ K+ + INI RG V+ L AL +++ A LDVT PEPLPT+HPL Sbjct: 210 STELFQQTKQQPMLINIGRGPAVDTTALMTALDHHQLSMAALDVTEPEPLPTDHPLWQRD 269 Query: 287 NCVILPHIGSATHRTRNTMSLLAANNLLAGLR-GEPMPSELKL 328 + +I PHI R T+ + A N ++ G + +++ L Sbjct: 270 DVLITPHISGQIAHFRATVFPIFAANFAQFVKDGTLVRNQVDL 312 >5DT9-A nrPDB Length = 387 Score = 227 bits (580), Expect = 4e-60, Method: Composition-based stats. Identities = 71/321 (22%), Positives = 122/321 (38%), Gaps = 40/321 (12%) Query: 1 MRPVRLMKVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLS 60 M + MK+ + +P + ++ + + A +L L+ Sbjct: 1 MPQIPTMKILIDENMPY-AQALFSQLGEV---ILKPGRTLTADDLI----DVDALMIRSV 52 Query: 61 DHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLL 120 V+ +L A LK + T + G+DH+ +++RGI P AE S+L+ Sbjct: 53 TKVNDALL-AKANRLKFVGTATAGMDHVDQALLRERGIFFTAAPGCNKVGVAEYVFSVLM 111 Query: 121 TTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRF 180 ++ G+ + TVGIIG G++G +A+ L G++ Sbjct: 112 VLAQQQ---------------------GFSVFDKTVGIIGAGQVGSYLAKCLSGIGMKVL 150 Query: 181 LYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPA----TEGLCNKDFFQKMKE 236 L P++A + EF L Q+D I + +T T L + ++++ Sbjct: 151 LNDP----PKQAQGDEREFTELETLLKQADVITLHTPITRGGEWPTHHLIDAAILEQLRS 206 Query: 237 TAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGS 296 + IN +RG VV+ L L G A LDV EP + LL L PHI Sbjct: 207 DQILINAARGPVVDNAALKARLQQGDGFTAVLDVFEFEP-QVDMELLPLL-AFATPHIAG 264 Query: 297 ATHRTRNTMSLLAANNLLAGL 317 + + + N+ L Sbjct: 265 YGLEGKARGTTMIFNSYCEFL 285 >4N18-A nrPDB Length = 332 Score = 227 bits (580), Expect = 4e-60, Method: Composition-based stats. Identities = 69/281 (24%), Positives = 108/281 (38%), Gaps = 12/281 (4%) Query: 47 RGVAGAHGLLCLLSDHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDV 106 + A C D L + LK+I S G+DHL + Sbjct: 59 QAARDAQYASCWFPDP----QLLSRSPGLKLIQAASAGVDHLPPALFASEIPLCRVIDED 114 Query: 107 LTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQ 166 E A+ +L R A+ + W + +GI+GLG IG Sbjct: 115 FRHGMFEYALWSVLWFQRHFDRALAHQRTQTWKLYPQRA-----AADFHIGIMGLGEIGG 169 Query: 167 AIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLC 226 IA +L G + ++ + + ++ E + D ++ LT T G+ Sbjct: 170 YIADQLARLGYRVSGWSRSEKQLAGVTCYRGE-EALDHFLGSLDGLINLLPLTAQTRGIL 228 Query: 227 NKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLK 286 F ++ AV IN RG+ + DD+ AL SG++A A LDV EPLP + PL Sbjct: 229 AAPLFNRLPAGAVLINCGRGEHMVNDDVLAALESGQLAGAVLDVFPQEPLPADDPLWRHP 288 Query: 287 NCVILPHIGSATHRTRNTMSLLAANNLLAGLRGEPMPSELK 327 VI PH+ SA ++ N+ RG P+ + + Sbjct: 289 QVVITPHMASAAPA--EVIARQLLENIQRQRRGLPLKNLVN 327 >4XKJ-A nrPDB Length = 335 Score = 226 bits (575), Expect = 2e-59, Method: Composition-based stats. Identities = 84/325 (25%), Positives = 132/325 (40%), Gaps = 24/325 (7%) Query: 9 VFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLSDHVDKRIL 68 +F R + +V+ + E + G G++ H+ + Sbjct: 5 MFSVRDDEEAAIREWEKKTGVQVDINRLE---LDAETAQLTKGYDGIVIQQRSHISNPAV 61 Query: 69 --DAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRL 126 L+ +++ + G D + L++ +RG+ V P ++ AELA++ + R L Sbjct: 62 YETLQKNGLRQLTSRTAGYDMIDLEQASERGLVVTNVPAYSPNSVAELALTQTMRLIRNL 121 Query: 127 PEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQ 186 P G ++ L + TVGIIG GRIG +AR K G Sbjct: 122 PLFDAR---GAEQDFRWAGLMAREIRSLTVGIIGAGRIGGTVARLFKALGATVIA---ND 175 Query: 187 PRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRG 246 + +VS EL +D + + L +T L + D MK AV IN SRG Sbjct: 176 IVERVELKDIVTYVSKEELLQAADVVTLHVPLMDSTTQLIDADALALMKNDAVLINASRG 235 Query: 247 DVVNQDDLYQALASGKIAAAGLDVTSPE-------------PLPTNHPLLTLKNCVILPH 293 VV+ D L AL + +IA A LD + E P L TL N +I PH Sbjct: 236 PVVDTDALIAALQNKQIAGAALDTLNGEEHFFNQDLCGKELPSEQLKVLRTLPNVLITPH 295 Query: 294 IGSATHRTRNTMSLLAANNLLAGLR 318 IG T++ M ++ N++LA L+ Sbjct: 296 IGFYTNKAVQNMVEISLNDVLAILK 320 >5TSD-A nrPDB Length = 322 Score = 217 bits (554), Expect = 4e-57, Method: Composition-based stats. Identities = 73/267 (27%), Positives = 109/267 (40%), Gaps = 17/267 (6%) Query: 62 HVDKRILDAAGANLKVISTMSVGIDHL-ALDEIKKRGIRVGYTPDVLTDTTAELAVSLLL 120 D + A NLKVI + G+DH+ + + I V + LT +E V L Sbjct: 57 KPDADLFRRA-PNLKVIFSGGAGVDHIIGMAGLPDIPI-VRFVDRSLTTRMSEWVVMQCL 114 Query: 121 TTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRF 180 R + W L + TVG++GLG +GQ +LK G Sbjct: 115 MHLRGQYGHDSHQRRREWAK-----LIAPEAAEVTVGVMGLGILGQDAVAKLKVMGFNVI 169 Query: 181 LYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETA-- 238 ++ + E F A A++D +V LTP T G + + F+K++ Sbjct: 170 GWSRTRKTIEGVETFDAG--ELDRFLAKTDILVGLLPLTPETTGFYDSELFKKLRRDGAL 227 Query: 239 ---VFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIG 295 VFIN RG + D+ A+ G + A LDV EPL T+ PL L+N I PH Sbjct: 228 GQPVFINAGRGKSQIETDIVSAVREGTLGGASLDVFEVEPLATDSPLWELENVFITPHDA 287 Query: 296 SATHRTRNTMSLLAANNLLAGLRGEPM 322 + + N + + RGEP+ Sbjct: 288 AVSEE--NALFRHVEMQIARFERGEPL 312 >4XA8-A nrPDB Length = 320 Score = 216 bits (551), Expect = 8e-57, Method: Composition-based stats. Identities = 74/256 (28%), Positives = 115/256 (44%), Gaps = 10/256 (3%) Query: 73 ANLKVISTMSVGIDH-LALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIE 131 NLK++ + G+D +A D++ + P+ ++ A + +L R +P Sbjct: 69 PNLKLVINLGAGVDALVARDDLPDVPVTRLSDPN-MSQMMASFVLFCVLRHARDIPTFER 127 Query: 132 EVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEE 191 + G W P + VG++GLG +G A A L G ++ R P+ E Sbjct: 128 AQREGRWHYVHP-----RTAAEIRVGVLGLGDLGAAAALELARHGFDVRGWS-RTPKALE 181 Query: 192 AAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQ 251 + P A S+ +VV LTP T GL N + + A FIN++RG VV++ Sbjct: 182 GVSCFHGLEALPGFLAGSEIVVVMLPLTPETRGLMNAERLAHLPRGAKFINVARGPVVDE 241 Query: 252 DDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTMSLLAAN 311 L AL SG IA A LDV EPLP PL + N ++ PH+ S T + Sbjct: 242 AALIAALRSGHIAEATLDVFEVEPLPVGSPLWAMDNVLVTPHLASIAI--PRTAAPQIVE 299 Query: 312 NLLAGLRGEPMPSELK 327 N+ GEP+ +++ Sbjct: 300 NIRRIEAGEPVLNQVD 315 >4NFY-A nrPDB Length = 307 Score = 216 bits (550), Expect = 1e-56, Method: Composition-based stats. Identities = 62/318 (19%), Positives = 123/318 (38%), Gaps = 38/318 (11%) Query: 7 MKVFVTRRIPAE------GRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLS 60 MK+ V P R L +A EV + + +++ + A G++ S Sbjct: 1 MKIVVITEKPFAENAVKGIREILEKAGH-EVVMIEKYKK--KEDVIERIKDADGVIVR-S 56 Query: 61 DHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLL 120 D +D+ I+ AG +K+I G D++ ++ + I V TP + AEL + +++ Sbjct: 57 DKIDEEII-KAGEKVKIIVRAGAGYDNIDIEACNQGKIVVMNTPGQNRNGVAELCIGMMI 115 Query: 121 TTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRF 180 R+ G+ K G L T+GI G G +G+ + + G++ Sbjct: 116 FGFRK-----------GFKEGK-----GRELKDKTLGICGCGYVGKRVKEIAEGIGMKIK 159 Query: 181 LYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVF 240 +Y + + EL + I + LT T+G + +K+ + Sbjct: 160 VYDPFITTENQVKK-------IEELFEECQVISLHLPLTKETKGKIGYELIKKLPYGGMI 212 Query: 241 INISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILP-HIGSATH 299 N +R ++++++ L + + + DV +P N+ P IG+ T Sbjct: 213 CNTARKEIIDEEGLIRIMREREDLIYITDV-APTSKVFNNEFKG--RFFATPIKIGAETE 269 Query: 300 RTRNTMSLLAANNLLAGL 317 + + AA+ + Sbjct: 270 ESNINAGMAAASQICDFF 287 >3OET-A nrPDB Length = 381 Score = 215 bits (548), Expect = 2e-56, Method: Composition-based stats. Identities = 71/315 (22%), Positives = 117/315 (37%), Gaps = 41/315 (13%) Query: 7 MKVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLSDHVDKR 66 MK+ V +P R +R + + PIP +EL A L+ V++ Sbjct: 4 MKILVDENMPY-ARELFSRLGEVKAV---PGRPIPVEELNH----ADALMVRSVTKVNES 55 Query: 67 ILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRL 126 +L G + + T + G DH+ +K+ GI P E S LL R Sbjct: 56 LLS--GTPINFVGTATAGTDHVDEAWLKQAGIGFSAAPGCNAIAVVEYVFSALLMLAER- 112 Query: 127 PEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQ 186 G+ L T+GI+G+G +G + RL+ G++ L Sbjct: 113 --------------------DGFSLRDRTIGIVGVGNVGSRLQTRLEALGIRTLLCDP-- 150 Query: 187 PRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPA----TEGLCNKDFFQKMKETAVFIN 242 P A + +F + EL ++D + L T L ++ +++K A+ IN Sbjct: 151 --PRAARGDEGDFRTLDELVQEADVLTFHTPLYKDGPYKTLHLADETLIRRLKPGAILIN 208 Query: 243 ISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTR 302 RG VV+ L L +G+ + LDV EP L + + HI T + Sbjct: 209 ACRGPVVDNAALLARLNAGQPLSVVLDVWEGEPDLNVALLEAVD--IGTSHIAGYTLEGK 266 Query: 303 NTMSLLAANNLLAGL 317 + A + Sbjct: 267 ARGTTQVFEAYSAFI 281 >3KBO-A nrPDB Length = 315 Score = 210 bits (536), Expect = 4e-55, Method: Composition-based stats. Identities = 66/264 (25%), Positives = 106/264 (40%), Gaps = 14/264 (5%) Query: 70 AAGANLKVISTMSVGIDHL-----ALDEIKKRGIRVGYTPDV-LTDTTAELAVSLLLTTC 123 AG LK + + G+D + A E+ I + D + E AVS +L Sbjct: 55 LAGRRLKAVFVLGAGVDAILSKLNAHPEMLDASIPLFRLEDTGMGLQMQEYAVSQVLHWF 114 Query: 124 RRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYT 183 RR + W L Y + +VGI+G G +G +A L+ +G ++ Sbjct: 115 RRFDDYQALKNQALWK-----PLPEYTREEFSVGIMGAGVLGAKVAESLQAWGFPLRCWS 169 Query: 184 GRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINI 243 R + E Q+ ++ T T G+ N + ++ + A +N+ Sbjct: 170 -RSRKSWPGVESYVGREELRAFLNQTRVLINLLPNTAQTVGIINSELLDQLPDGAYVLNL 228 Query: 244 SRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRN 303 +RG V + DL AL SGK+ A LDV S EPLP PL + PHI + T Sbjct: 229 ARGVHVQEADLLAALDSGKLKGAMLDVFSQEPLPQESPLWRHPRVAMTPHIAAVTRPA-- 286 Query: 304 TMSLLAANNLLAGLRGEPMPSELK 327 + + +GEP+ ++ Sbjct: 287 EAIDYISRTITQLEKGEPVTGQVD 310 >4WEQ-A nrPDB Length = 341 Score = 207 bits (528), Expect = 5e-54, Method: Composition-based stats. Identities = 75/331 (22%), Positives = 123/331 (37%), Gaps = 24/331 (7%) Query: 3 PVRLMKVFVTRRIPAEGRVALARAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLSDH 62 P + + + IP E ALA A E I + G+ + Sbjct: 24 PAKSPVIVDLKFIPEEVEAALAGAF-------PGREVIDLADPAHQERDLSGIDYAVVWK 76 Query: 63 VDKRILDAAGANLKVISTMSVGIDHL-ALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLT 121 + A +LKV+ + G+DH+ L + + V + LT +E + L Sbjct: 77 SAPDLFSRA-PDLKVVFSGGAGVDHVLTLPGLPDVPL-VRFVDRTLTTRMSEWVMMQCLL 134 Query: 122 TCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFL 181 R+ K W L TVGI+G+G +GQ AR+L G + Sbjct: 135 HLRQHRAYEALAKKHEWRD-----LSQPEAADVTVGIMGMGVLGQDAARKLAAMGFKVIG 189 Query: 182 YTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETA--- 238 ++ + E + A ++DF+V LTP T G+ N F K+ Sbjct: 190 WSRSKRVIEGVETYDA--AGLDAFLGRTDFLVGLLPLTPDTRGIFNAALFAKLSRNGPFG 247 Query: 239 --VFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGS 296 VFIN RG + D+ + L SG + A LDV EPL + N + PH+ + Sbjct: 248 APVFINAGRGGSQVEADILECLDSGVLGGASLDVFEREPLSPESRFWDMPNVYVTPHVAA 307 Query: 297 ATHRTRNTMSLLAANNLLAGLRGEPMPSELK 327 ++ + + + + G P+ + Sbjct: 308 SSD--VRALFVHVEHQIARFESGLPLEHVVD 336 >4HY3-A nrPDB Length = 365 Score = 200 bits (509), Expect = 6e-52, Method: Composition-based stats. Identities = 69/261 (26%), Positives = 114/261 (43%), Gaps = 2/261 (0%) Query: 62 HVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLT 121 + L A +++ S ++++ + + +RGI V T V + AE+ + L Sbjct: 85 PLSAETLARMPALRSILNVESNLLNNMPYEVLFQRGIHVVTTGQVFAEPVAEIGLGFALA 144 Query: 122 TCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFL 181 R + +A + G + S +GI+G G +G+A+ R L F + + Sbjct: 145 LARGIVDADIAFQEGTELWGGEGNASARLIAGSEIGIVGFGDLGKALRRVLSGFRARIRV 204 Query: 182 YTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFI 241 + PR E E S ++ +SDFI V ++T + + F M+ A FI Sbjct: 205 FDPWLPRSMLE-ENGVEPASLEDVLTKSDFIFVVAAVTSENKRFLGAEAFSSMRRGAAFI 263 Query: 242 NISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRT 301 +SR DVV+ D L A++SG I A DV EPLP +HP+ +LK + H A Sbjct: 264 LLSRADVVDFDALMAAVSSGHIV-AASDVYPEEPLPLDHPVRSLKGFIRSAHRAGALDSA 322 Query: 302 RNTMSLLAANNLLAGLRGEPM 322 M + ++ RG P Sbjct: 323 FKKMGDMVLEDMDLMDRGLPP 343 >3GVX-A nrPDB Length = 290 Score = 194 bits (492), Expect = 6e-50, Method: Composition-based stats. Identities = 69/283 (24%), Positives = 112/283 (39%), Gaps = 20/283 (7%) Query: 44 ELERGVAGAHGLLCLLSDHVDKRILDAA-----GANLKVISTMSVGIDHLALDEIKKRGI 98 E+ + V L D+ D G K+I +S G+DH+ ++ I + + Sbjct: 15 EIAKTVLDGFDLHWY-PDYYDAEAQVIKDRYVLGKRTKMIQAISAGVDHIDVNGIPE-NV 72 Query: 99 RVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGI 158 + + + AE A +LLL + + E E +K G + L G L G Sbjct: 73 VLCSNAGAYSISVAEHAFALLLAHAKNILENNELMKAGIFRQSPTTLLYGKALGILGYGG 132 Query: 159 IGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSL 218 I G+ +A K FG++ YT S +L QSDF+++A L Sbjct: 133 I-----GRRVAHLAKAFGMRVIAYTRSSVDQNV----DVISESPADLFRQSDFVLIAIPL 183 Query: 219 TPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPT 278 T T G+ N ++ +N++R DVV++ D+ L DV EP T Sbjct: 184 TDKTRGMVNSRLLANARKNLTIVNVARADVVSKPDMIGFLKERSDVWYLSDVWWNEPEIT 243 Query: 279 NHPLLTLKNCVILPHI-GSATHRTRNTMSLLAANNLLAGLRGE 320 L+N ++ PH+ G + + LA N+ GE Sbjct: 244 E---TNLRNAILSPHVAGGMSGEIMDIAIQLAFENVRNFFEGE 283 >5C5I-A nrPDB Length = 316 Score = 194 bits (492), Expect = 6e-50, Method: Composition-based stats. Identities = 78/322 (24%), Positives = 123/322 (38%), Gaps = 19/322 (5%) Query: 6 LMKVFVTRRIPAEGRVALA--RAADCEVEQWDSDEPIPAKELERGVAGAHGLLCLLSDHV 63 + ++ + R+ E A A E+ D + E + D Sbjct: 4 MSRIALVTRLSPEAEAHWAGHLARALPGERIDGFRELSPAERAE----VDIAIVANPDPA 59 Query: 64 DKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTC 123 D A NL I ++ G++ L + V L T AE A++ Sbjct: 60 D----LAELPNLVWIHSLWAGVERLVAELGHLARPIVRLVDPELARTMAEAALAWTYYLF 115 Query: 124 RRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYT 183 R +P + + W L ++TVG++GLG +G A A RL+ G ++ Sbjct: 116 RDMPAYAAQQRARVWKG-----LPYKRPERTTVGVLGLGELGAAAALRLRDAGFDVHGWS 170 Query: 184 GRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINI 243 R P+ A + + Q + +V LT T GL + + E A +N Sbjct: 171 -RSPKEIAGVTCHAGEETLERMLGQVEILVCLLPLTGETRGLLDARRLACLPEGAQIVNF 229 Query: 244 SRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATH-RTR 302 +RG +++ L +AL SG+I A LDV EPLP P +LPHI +AT T Sbjct: 230 ARGPILDSAALIEALDSGRIGHAVLDVFEVEPLPEASPFWGHPKVTVLPHISAATDPETA 289 Query: 303 NTMSLLAANNLLAGLRGEPMPS 324 + + + A G PS Sbjct: 290 SAIVGAHVADYRA--TGRIPPS 309 >1QP8-A nrPDB Length = 303 Score = 190 bits (484), Expect = 5e-49, Method: Composition-based stats. Identities = 68/279 (24%), Positives = 107/279 (38%), Gaps = 18/279 (6%) Query: 47 RGVAGAHG--LLCLLSDHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTP 104 + V G + L + L A LK I ++ G+DHL + I + V Sbjct: 22 KIVRGGDLGNVEAALVSRITAEEL-AKMPRLKFIQVVTAGLDHLPWESIPPH-VTVAGNA 79 Query: 105 DVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRI 164 D AE A++LLL +R+ + E++K G + + L + V ++GLG I Sbjct: 80 GSNADAVAEFALALLLAPYKRIIQYGEKMKRGDYGRDVEIPL----IQGEKVAVLGLGEI 135 Query: 165 GQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFV-STPELAAQSDFIVVACSLTPATE 223 G + + L G Q ++ E F S E ++ V A L T Sbjct: 136 GTRVGKILAALGAQVRGFS------RTPKEGPWRFTNSLEEALREARAAVCALPLNKHTR 189 Query: 224 GLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSP-EPLPTNHPL 282 GL M E AVF+N+ R +V+++D + + L DV + Sbjct: 190 GLVKYQHLALMAEDAVFVNVGRAEVLDRDGVLRILKERPQFIFASDVWWGRNDFAKDAEF 249 Query: 283 LTLKNCVILPHI--GSATHRTRNTMSLLAANNLLAGLRG 319 +L N V P + G R M + A NL+ G Sbjct: 250 FSLPNVVATPWVAGGYGNERVWRQMVMEAVRNLITYATG 288 >2O4C-A nrPDB Length = 380 Score = 180 bits (456), Expect = 9e-46, Method: Composition-based stats. Identities = 66/268 (24%), Positives = 105/268 (39%), Gaps = 34/268 (12%) Query: 38 EPIPAKELERGV-AGAHGLLCLLSDHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKR 96 +P + ++R A LL V + L AG+ ++ + T ++G DHL LD + Sbjct: 23 RRLPGRAIDRAALAEVDVLLVRSVTEVSRAAL--AGSPVRFVGTCTIGTDHLDLDYFAEA 80 Query: 97 GIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTV 156 GI P + + LL A+ EV+ G L + T Sbjct: 81 GIAWSSAPGCNARGVVDYVLGCLL--------AMAEVR-------------GADLAERTY 119 Query: 157 GIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVAC 216 G++G G++G + L+ G + + P +A E EFVS L A++D I + Sbjct: 120 GVVGAGQVGGRLVEVLRGLGWKVLVCDP----PRQAREPDGEFVSLERLLAEADVISLHT 175 Query: 217 SLTPA----TEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTS 272 L T L ++ ++ +N SRG VV+ L + L G LDV Sbjct: 176 PLNRDGEHPTRHLLDEPRLAALRPGTWLVNASRGAVVDNQALRRLLEGGADLEVALDVWE 235 Query: 273 PEPLPTNHPLLTLKNCVILPHIGSATHR 300 EP P L + + PHI + Sbjct: 236 GEP--QADPELAARCLIATPHIAGYSLE 261 >3H9U-A nrPDB Length = 436 Score = 55.7 bits (133), Expect = 2e-08, Method: Composition-based stats. Identities = 17/94 (18%), Positives = 38/94 (40%), Gaps = 4/94 (4%) Query: 151 LTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSD 210 + T + G G +G+ A L+ FG + + +AA + + ++ ++ Sbjct: 209 IAGKTACVCGYGDVGKGCAAALRGFGARVVVTEVDPINALQAAMEGYQVLLVEDVVEEAH 268 Query: 211 FIVVACSLTPATEGLCNKDFFQKMKETAVFINIS 244 V T + + + F +M++ A+ NI Sbjct: 269 IFVT----TTGNDDIITSEHFPRMRDDAIVCNIG 298 >5JXW-A nrPDB Length = 498 Score = 55.0 bits (131), Expect = 4e-08, Method: Composition-based stats. Identities = 17/94 (18%), Positives = 38/94 (40%), Gaps = 4/94 (4%) Query: 151 LTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSD 210 L + ++G G +G+ A+ L G + + +A+ + ++ +++D Sbjct: 269 LAGKKIVVLGYGEVGKGCAQGLSGVGARVIVTEIDPICALQASMEGYQVSVLEDVVSEAD 328 Query: 211 FIVVACSLTPATEGLCNKDFFQKMKETAVFINIS 244 + A + + + +KMKE A NI Sbjct: 329 IFITAT----GNKDVITVEHMRKMKENAYIANIG 358 >3G1U-A nrPDB Length = 437 Score = 53.4 bits (127), Expect = 1e-07, Method: Composition-based stats. Identities = 18/94 (19%), Positives = 36/94 (38%), Gaps = 4/94 (4%) Query: 151 LTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSD 210 + T + G G +G+ A L+ FG + + +A+ + ++ A + Sbjct: 210 IAGKTCCVCGYGDVGKGCAAALRAFGARVVVTEVDPINALQASMEGYQVALVEDVMADAH 269 Query: 211 FIVVACSLTPATEGLCNKDFFQKMKETAVFINIS 244 V T + + D F M++ A+ NI Sbjct: 270 IFVT----TTGNDDIITSDHFPHMRDDAIVCNIG 299 >3D64-A nrPDB Length = 494 Score = 52.7 bits (125), Expect = 2e-07, Method: Composition-based stats. Identities = 19/94 (20%), Positives = 35/94 (37%), Gaps = 4/94 (4%) Query: 151 LTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSD 210 + + G G +G+ A+ L+ G ++ +AA V+ A ++D Sbjct: 275 IAGKIAVVAGYGDVGKGCAQSLRGLGATVWVTEIDPICALQAAMEGYRVVTMEYAADKAD 334 Query: 211 FIVVACSLTPATEGLCNKDFFQKMKETAVFINIS 244 V A + N D + M+ A+ NI Sbjct: 335 IFVTAT----GNYHVINHDHMKAMRHNAIVCNIG 364 >6JCV-A nrPDB Length = 333 Score = 51.9 bits (123), Expect = 3e-07, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 27/67 (40%) Query: 151 LTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSD 210 L T+G+IG G G+ A ++ G+ + + E A + E E +SD Sbjct: 13 LKGKTIGVIGYGNQGRVQATIMRENGLNVIVGNVKDKYYELAKKEGFEVYEIDEAVRRSD 72 Query: 211 FIVVACS 217 ++ Sbjct: 73 VALLLIP 79 >6GBN-A nrPDB Length = 438 Score = 51.9 bits (123), Expect = 4e-07, Method: Composition-based stats. Identities = 16/94 (17%), Positives = 35/94 (37%), Gaps = 4/94 (4%) Query: 151 LTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSD 210 + + G G +G+ A L+ G + + +AA E + ++D Sbjct: 217 MAGKVAVVAGYGDVGKGSAASLRGAGARVIVTEIDPICALQAAMDGYEVKKMADAVKRAD 276 Query: 211 FIVVACSLTPATEGLCNKDFFQKMKETAVFINIS 244 +V A + + + F+ M++ + NI Sbjct: 277 IVVTAT----GNKNIITGEHFKAMRDKVIVCNIG 306 >3NJ4-A nrPDB Length = 435 Score = 51.1 bits (121), Expect = 6e-07, Method: Composition-based stats. Identities = 20/97 (20%), Positives = 37/97 (38%), Gaps = 10/97 (10%) Query: 151 LTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSD 210 + + G G +G+ A+ L+ FG + + +AA E + E + + Sbjct: 214 IAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQEGN 273 Query: 211 FIVVACSLTPATEGLCN---KDFFQKMKETAVFINIS 244 V T G + F++MK+ A+ NI Sbjct: 274 IFV-------TTTGCIDIILGRHFEQMKDDAIVCNIG 303 >2ZJ1-A nrPDB Length = 495 Score = 50.7 bits (120), Expect = 8e-07, Method: Composition-based stats. Identities = 19/94 (20%), Positives = 36/94 (38%), Gaps = 4/94 (4%) Query: 151 LTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSD 210 + V I G G +G+ A +K G + + +A + V+ E +D Sbjct: 273 IGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEIDPINALQAMMEGFDVVTVEEAIGDAD 332 Query: 211 FIVVACSLTPATEGLCNKDFFQKMKETAVFINIS 244 +V A + + + + MK+ A+ NI Sbjct: 333 IVVTAT----GNKDIIMLEHIKAMKDHAILGNIG 362 >3N58-A nrPDB Length = 464 Score = 49.2 bits (116), Expect = 3e-06, Method: Composition-based stats. Identities = 22/110 (20%), Positives = 43/110 (39%), Gaps = 7/110 (6%) Query: 151 LTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSD 210 + + G G +G+ A+ L G + + +AA E V+ + A+ +D Sbjct: 245 MAGKVAVVCGYGDVGKGSAQSLAGAGARVKVTEVDPICALQAAMDGFEVVTLDDAASTAD 304 Query: 211 FIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALAS 260 +V T + + D +KMK+ + NI + + AL + Sbjct: 305 IVVT----TTGNKDVITIDHMRKMKDMCIVGNIG---HFDNEIQVAALRN 347 >3X2F-A nrPDB Length = 411 Score = 48.8 bits (115), Expect = 3e-06, Method: Composition-based stats. Identities = 19/94 (20%), Positives = 34/94 (36%), Gaps = 4/94 (4%) Query: 151 LTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSD 210 + V + G G G+ IA R G + + + EA + E +D Sbjct: 195 VAGKNVVVAGYGWCGRGIALRAAGLGARVIVTEVDPVKAVEAIMDGFTVMPMKEAVKIAD 254 Query: 211 FIVVACSLTPATEGLCNKDFFQKMKETAVFINIS 244 F++ A + +K+ +K+ AV N Sbjct: 255 FVITA----SGNTDVLSKEDILSLKDGAVLANAG 284 >3OND-A nrPDB Length = 488 Score = 48.4 bits (114), Expect = 4e-06, Method: Composition-based stats. Identities = 18/94 (19%), Positives = 37/94 (39%), Gaps = 4/94 (4%) Query: 151 LTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSD 210 + + G G +G+ A LK G + + +A + ++ ++ +++D Sbjct: 263 IAGKVAVVAGYGDVGKGCAAALKQAGARVIVTEIDPICALQATMEGLQVLTLEDVVSEAD 322 Query: 211 FIVVACSLTPATEGLCNKDFFQKMKETAVFINIS 244 V T + + D +KMK A+ NI Sbjct: 323 IFVT----TTGNKDIIMLDHMKKMKNNAIVCNIG 352 >5M65-A nrPDB Length = 479 Score = 48.4 bits (114), Expect = 4e-06, Method: Composition-based stats. Identities = 21/110 (19%), Positives = 43/110 (39%), Gaps = 7/110 (6%) Query: 151 LTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSD 210 L+ + G G +G+ A L+ G + + +AA E V+ + A ++D Sbjct: 258 LSGKVAMVAGFGDVGKGSAASLRQAGCRVMVSEVDPICALQAAMEGYEVVTMEDAAPRAD 317 Query: 211 FIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALAS 260 V A + + + + MK+ A+ NI + + +L + Sbjct: 318 IFVTAT----GNKDIITIEHMRAMKDRAIVCNIG---HFDNEIQIASLRN 360 >6APH-A nrPDB Length = 445 Score = 48.0 bits (113), Expect = 5e-06, Method: Composition-based stats. Identities = 20/94 (21%), Positives = 34/94 (36%), Gaps = 4/94 (4%) Query: 151 LTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSD 210 L V + G G +G+ A + G + +AA E + +D Sbjct: 224 LAGKRVVVCGFGDVGKGTAASFRGAGSIVTVTEIDPICALQAAMEGYEVKQLDTVVDNAD 283 Query: 211 FIVVACSLTPATEGLCNKDFFQKMKETAVFINIS 244 I+ T G+ + F+KMK+ + NI Sbjct: 284 IIIT----TTGNFGIVRGEHFEKMKDKTIVCNIG 313 >1V8B-A nrPDB Length = 479 Score = 48.0 bits (113), Expect = 6e-06, Method: Composition-based stats. Identities = 20/94 (21%), Positives = 35/94 (37%), Gaps = 4/94 (4%) Query: 151 LTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSD 210 ++ V I G G +G+ A +K G + ++ +A V+ E+ + D Sbjct: 255 ISGKIVVICGYGDVGKGCASSMKGLGARVYITEIDPICAIQAVMEGFNVVTLDEIVDKGD 314 Query: 211 FIVVACSLTPATEGLCNKDFFQKMKETAVFINIS 244 F + + + KMK AV NI Sbjct: 315 FFITCT----GNVDVIKLEHLLKMKNNAVVGNIG 344 >2RIR-A nrPDB Length = 300 Score = 47.3 bits (111), Expect = 8e-06, Method: Composition-based stats. Identities = 27/163 (16%), Positives = 45/163 (27%), Gaps = 11/163 (6%) Query: 86 DHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTC-RRLPEAIEEVKNGGWTSWKPL 144 DHL + + + A A L+ R + T + Sbjct: 91 DHLD--RTPAHCVIFSGISNAYLENIAAQAKRKLVKLFERDDIAIYNSIPTVEGTIMLAI 148 Query: 145 WLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPE 204 Y + S V ++GLGR G IAR G + E T E Sbjct: 149 QHTDYTIHGSQVAVLGLGRTGMTIARTFAALGANVKVGARSSAHLARITEMGLVPFHTDE 208 Query: 205 L---AAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINIS 244 L D + + N+ M + ++++ Sbjct: 209 LKEHVKDIDICINTIPSM-----ILNQTVLSSMTPKTLILDLA 246 >5H82-A nrPDB Length = 389 Score = 45.7 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 16/62 (25%), Positives = 28/62 (45%) Query: 136 GGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEF 195 GG + P+ G ++G++G GRIG+ + K FG + + + +EA E Sbjct: 196 GGIVPYSPMRHFGLDKPGLSIGVVGFGRIGKLAVKFAKAFGANVTVISTSISKKQEAIEK 255 Query: 196 QA 197 Sbjct: 256 YG 257 >2VHY-A nrPDB Length = 377 Score = 45.3 bits (106), Expect = 3e-05, Method: Composition-based stats. Identities = 20/126 (15%), Positives = 37/126 (29%), Gaps = 13/126 (10%) Query: 129 AIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPR 188 A ++ G + G V +IG G G AR G + + Sbjct: 146 AYHLMRTQGGRGVLMGGVPGVEPAD--VVVIGAGTAGYNAARIANGMGATVTVLDINIDK 203 Query: 189 PEEAAEFQAEFV--------STPELAAQSDFIV--VACSLTPATEGLCNKDFFQKMKETA 238 + + ++D ++ V A + L + MK A Sbjct: 204 LRQLDAEFCGRIHTRYSSAYELEGAVKRADLVIGAVLVPGAKAPK-LVSNSLVAHMKPGA 262 Query: 239 VFINIS 244 V ++I+ Sbjct: 263 VLVDIA 268 >6C55-A nrPDB Length = 340 Score = 45.0 bits (105), Expect = 5e-05, Method: Composition-based stats. Identities = 16/67 (23%), Positives = 26/67 (38%) Query: 151 LTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSD 210 L + ++G G G A A+ LK G + ++A E + E Q+D Sbjct: 15 LQGKKIAVVGYGSQGHAHAQNLKDNGYDVVIGIRPGRSFDKAKEDGFDVFPVAEAVKQAD 74 Query: 211 FIVVACS 217 I+V Sbjct: 75 VIMVLLP 81 >4XDY-A nrPDB Length = 338 Score = 42.3 bits (98), Expect = 3e-04, Method: Composition-based stats. Identities = 19/98 (19%), Positives = 36/98 (36%), Gaps = 9/98 (9%) Query: 151 LTQSTVGIIGLGRIGQAIARRLKPFGVQR------FLYTGRQPRPEEAAEFQAEFVSTPE 204 L T+ ++G G G A A LK G+ L + P E+A E E + + Sbjct: 14 LRDKTIAVMGYGAQGDAQANCLKDSGINVVIGETEILGGNKNPSWEKAKEDGFEVLPIDK 73 Query: 205 LAAQSDFIVVACSLTPATEGLCNKDFFQ-KMKETAVFI 241 A + D + + + ++ + ++K Sbjct: 74 AAEKGDVVHILLP--DEVQPAIYENQIKPQLKAGKALC 109 >4XDZ-A nrPDB Length = 343 Score = 41.9 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 21/92 (22%), Positives = 35/92 (38%), Gaps = 2/92 (2%) Query: 151 LTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRP-EEAAEFQAEFVSTPELAAQS 209 + T+ I+G G G+A A L+ G+ + RQ A + + + T + A + Sbjct: 15 IKNKTIAILGYGSQGRAWALNLRDSGLNVVVGLERQGDSWRRAIDDGFKPMYTKDAVAIA 74 Query: 210 DFIVVACSLTPATEGLCNKDFFQKMKETAVFI 241 D IV N MK+ A + Sbjct: 75 DIIVFLVPDMVQKSLWLNSVK-DFMKKGADLV 105 >5E4R-A nrPDB Length = 490 Score = 41.9 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 21/92 (22%), Positives = 35/92 (38%), Gaps = 2/92 (2%) Query: 151 LTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRP-EEAAEFQAEFVSTPELAAQS 209 + T+ I+G G G+A A L+ G+ + RQ A + + + T + A + Sbjct: 15 IKNKTIAILGYGSQGRAWALNLRDSGLNVVVGLERQGDSWRRAIDDGFKPMYTKDAVAIA 74 Query: 210 DFIVVACSLTPATEGLCNKDFFQKMKETAVFI 241 D IV N MK+ A + Sbjct: 75 DIIVFLVPDMVQKSLWLNSVK-DFMKKGADLV 105 >5U5G-A nrPDB Length = 295 Score = 41.5 bits (96), Expect = 6e-04, Method: Composition-based stats. Identities = 19/96 (19%), Positives = 40/96 (41%), Gaps = 4/96 (4%) Query: 153 QSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFV-STPELAAQSDF 211 VG IGLGR+GQAI RRL + ++ + + ++ A + L + Sbjct: 2 NRVVGFIGLGRMGQAICRRLLASQMPVHVHNRSREKADDLIRQGAVWAPDIVALTRAARV 61 Query: 212 IVVACSLTPAT---EGLCNKDFFQKMKETAVFINIS 244 + V + + A ++ ++ + +++S Sbjct: 62 LFVCTAGSEAVQDFYHAPDRGLLACLEVGDIVVDLS 97 >2EEZ-A nrPDB Length = 369 Score = 41.5 bits (96), Expect = 6e-04, Method: Composition-based stats. Identities = 33/180 (18%), Positives = 63/180 (35%), Gaps = 16/180 (8%) Query: 91 DEIKKRGIR-VGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGY 149 + + + G+ + Y L D T L V + R P+ + L Sbjct: 103 EAMLRSGVTGIAYETVQLPDGTLPLLVPMSEVAGRMAPQVGAQFLEKPKGGRGVLLGGVP 162 Query: 150 GLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPE--------EAAEFQAEFVS 201 G+ ++V I+G G +G A+ G Q + R + A + Sbjct: 163 GVAPASVVILGGGTVGTNAAKIALGMGAQVTILDVNHKRLQYLDDVFGGRVITLTATEAN 222 Query: 202 TPELAAQSDFIV--VACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALA 259 + +D ++ V A + L +D MKE AV ++++ V+Q + + Sbjct: 223 IKKSVQHADLLIGAVLVPGAKAPK-LVTRDMLSLMKEGAVIVDVA----VDQGGCVETIR 277 >4TSK-A nrPDB Length = 350 Score = 40.7 bits (94), Expect = 8e-04, Method: Composition-based stats. Identities = 14/67 (20%), Positives = 25/67 (37%) Query: 151 LTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSD 210 L + +IG G G A A+ L+ G + +A ++ E +SD Sbjct: 15 LADKRIAVIGYGSQGHAHAQNLRDSGFDVVIGLRPGSSWAKAEADGFRVMAVGEAVEESD 74 Query: 211 FIVVACS 217 I++ Sbjct: 75 VIMILLP 81 >1X14-A nrPDB Length = 401 Score = 40.7 bits (94), Expect = 8e-04, Method: Composition-based stats. Identities = 36/224 (16%), Positives = 72/224 (32%), Gaps = 40/224 (17%) Query: 55 LLCLLSDHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIRVGYTPDVLTDTTAEL 114 ++ ++ +D + ++S + + + ++ +R + V V + A+ Sbjct: 75 IILKVNAPLDDE-IALLNPGTTLVSFIWPAQNPELMQKLAERNVTVMAMDSVPRISRAQS 133 Query: 115 --AVSLL--LTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIAR 170 A+S + + R + EA G + G + +IG G G A Sbjct: 134 LDALSSMANIAGYRAIVEA---AHEFGRFFTGQITAAGKVPPAKVM-VIGAGVAGLAAIG 189 Query: 171 RLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTP------------------------ELA 206 G + R E+ AEF+ EL Sbjct: 190 AANSLGAIVRAFDTRPEVKEQVQSMGAEFLELDFKEEAGSGDGYAKVMSDAFIKAEMELF 249 Query: 207 A----QSDFIVV--ACSLTPATEGLCNKDFFQKMKETAVFINIS 244 A + D IV PA + L ++ MK +V ++++ Sbjct: 250 AAQAKEVDIIVTTALIPGKPAPK-LITREMVDSMKAGSVIVDLA 292 >2GF2-A nrPDB Length = 296 Score = 40.7 bits (94), Expect = 9e-04, Method: Composition-based stats. Identities = 23/99 (23%), Positives = 41/99 (41%), Gaps = 17/99 (17%) Query: 156 VGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFV--STPELAAQSDFIV 213 VG IGLG +G +A+ L G +Y P + + E V S ++A ++D I+ Sbjct: 3 VGFIGLGNMGNPMAKNLMKHGYPLIIYDV-FPDACKEFQDAGEQVVSSPADVAEKADRII 61 Query: 214 VACSLTPATEGLCNK--------DFFQKMKETAVFINIS 244 + N +K+K+ ++ I+ S Sbjct: 62 TMLPTS------INAIEAYSGANGILKKVKKGSLLIDSS 94 >4KQW-A nrPDB Length = 350 Score = 40.0 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 18/68 (26%), Positives = 25/68 (36%), Gaps = 1/68 (1%) Query: 151 LTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRP-EEAAEFQAEFVSTPELAAQS 209 + VGIIG G G A A L GV + + A E + A ++ Sbjct: 25 IQGLKVGIIGYGSQGHAHALNLMDSGVDVRVGLREGSSSWKTAEEAGLKVTDMDTAAEEA 84 Query: 210 DFIVVACS 217 D I+V Sbjct: 85 DVIMVLVP 92 >4WJI-A nrPDB Length = 293 Score = 39.6 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 24/103 (23%), Positives = 44/103 (42%), Gaps = 9/103 (8%) Query: 154 STVGIIGLGRIGQAIAR--RLKPFGVQRFLYTGRQPRPEEAAEFQAE---FVSTPELAAQ 208 T+ +IG+G IG +IAR R K + T + + A E +S E Sbjct: 5 QTIALIGIGLIGSSIARDIREKQLAGTIVVTTRSEATLKRAGELGLGDRYTLSAAEAVEG 64 Query: 209 SDFIVVACSLTPATEGLCNKDFFQKMKETAVFINIS--RGDVV 249 +D +VV+ + + G + +K A+ ++ +G V+ Sbjct: 65 ADLVVVSVPVGAS--GAVAAEIAAHLKPGAIVTDVGSTKGSVI 105 >4YPO-A nrPDB Length = 333 Score = 39.6 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 2/88 (2%) Query: 151 LTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTP-ELAAQS 209 + VG+IG G G A + L+ GVQ + + R E Q V TP E+A + Sbjct: 12 IQGRKVGVIGYGSQGHAHSLSLRDSGVQVRVGLKQGSRSRPKVEEQGLDVDTPAEVAKWA 71 Query: 210 DFIVVACSLTPATEGLCNKDFFQKMKET 237 D ++V T E + D +K Sbjct: 72 DVVMVLAPDTAQAE-IFAGDIEPNLKPG 98 >5YEQ-A nrPDB Length = 340 Score = 39.6 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 15/68 (22%), Positives = 30/68 (44%), Gaps = 1/68 (1%) Query: 151 LTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRP-EEAAEFQAEFVSTPELAAQS 209 + + V ++G G G+A A L+ G++ + R+ ++A + + T E S Sbjct: 15 IKEKRVAVLGYGSQGRAWALNLRDSGIKVSVGLEREGNSWKQAENDGFKPLRTEEAVRNS 74 Query: 210 DFIVVACS 217 D I+ Sbjct: 75 DIIIFLLP 82 >1V9L-A nrPDB Length = 421 Score = 39.2 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 28/166 (16%), Positives = 49/166 (29%), Gaps = 26/166 (15%) Query: 97 GIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTV 156 G+ P++ + E A + A E+ W G+ TV Sbjct: 170 GVFTSKPPELWGNPVREYATGF------GVAVATREMAKKLWG----------GIEGKTV 213 Query: 157 GIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVAC 216 I G+G +G+ A L+ G + + E + + + + Sbjct: 214 AIQGMGNVGRWTAYWLEKMGAKVIAVSDINGVAYRKEGLNVELIQKNKGLTGPALVELFT 273 Query: 217 SLTPATEGLC-NKDFFQKMKET----AVFINISRGDVVNQDDLYQA 257 T N D K+ A N+ RG + L +A Sbjct: 274 --TKDNAEFVKNPDAIFKLDVDIFVPAAIENVIRG---DNAGLVKA 314 >1VPD-A nrPDB Length = 299 Score = 39.2 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 28/132 (21%), Positives = 52/132 (39%), Gaps = 3/132 (2%) Query: 154 STVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPE-LAAQSDFI 212 VG IGLG +G+ +++ L G + + AE ST + +A Q D I Sbjct: 6 MKVGFIGLGIMGKPMSKNLLKAGYSLVVSDRNPEAIADVIAAGAETASTAKAIAEQCDVI 65 Query: 213 VVACSLTPATEGLCNKD--FFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDV 270 + +P + + + + K V I++S + ++ AL + + V Sbjct: 66 ITMLPNSPHVKEVALGENGIIEGAKPGTVLIDMSSIAPLASREISDALKAKGVEMLDAPV 125 Query: 271 TSPEPLPTNHPL 282 + EP + L Sbjct: 126 SGGEPKAIDGTL 137 >3B1F-A nrPDB Length = 290 Score = 39.2 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 22/100 (22%), Positives = 39/100 (39%), Gaps = 8/100 (8%) Query: 151 LTQSTVGIIGLGRIGQAIA---RRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPE--- 204 + + T+ I GLG IG ++A +R P + Y + A E +T + Sbjct: 4 MEEKTIYIAGLGLIGASLALGIKRDHPH-YKIVGYNRSDRSRDIALERGIVDEATADFKV 62 Query: 205 LAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINIS 244 AA +D I++A + T +KE + + Sbjct: 63 FAALADVIILAVPI-KKTIDFIKILADLDLKEDVIITDAG 101 >1GPJ-A nrPDB Length = 404 Score = 38.8 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 5/72 (6%) Query: 150 GLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQ--PRPEEAAEFQAEFVSTPEL-- 205 L TV ++G G +G+ +A+ L GV+ L R E A + E V EL Sbjct: 164 SLHDKTVLVVGAGEMGKTVAKSLVDRGVRAVLVANRTYERAVELARDLGGEAVRFDELVD 223 Query: 206 -AAQSDFIVVAC 216 A+SD +V A Sbjct: 224 HLARSDVVVSAT 235 >1BVU-A nrPDB Length = 418 Score = 38.8 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 12/79 (15%), Positives = 30/79 (37%), Gaps = 6/79 (7%) Query: 130 IEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRL-KPFGVQRFLYTGRQPR 188 + +T + G L T+ I G G G +A+ + + +G++ + Sbjct: 188 DATARGASYTVREAAKALGMDLKGKTIAIQGYGNAGYYMAKIMSEEYGMKVVAVSDT--- 244 Query: 189 PEEAAEFQAEFVSTPELAA 207 + + + ++ E+ A Sbjct: 245 --KGGIYNPDGLNADEVLA 261 >3TWO-A nrPDB Length = 348 Score = 38.0 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 11/68 (16%), Positives = 26/68 (38%), Gaps = 2/68 (2%) Query: 152 TQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTP--ELAAQS 209 + VG+ G G +G + G + ++ + + ++A + T + + Sbjct: 176 KGTKVGVAGFGGLGSMAVKYAVAMGAEVSVFARNEHKKQDALSMGVKHFYTDPKQCKEEL 235 Query: 210 DFIVVACS 217 DFI+ Sbjct: 236 DFIISTIP 243 >5G6R-A nrPDB Length = 295 Score = 37.6 bits (86), Expect = 0.007, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 28/64 (43%), Gaps = 1/64 (1%) Query: 154 STVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVST-PELAAQSDFI 212 +GI GLG +G A+A + G + ++ + E A+ ST E +D I Sbjct: 3 KHIGIFGLGAMGTALAAKYLEHGYKTSVWNRTTAKAIPLVEQGAKLASTISEGVNANDLI 62 Query: 213 VVAC 216 ++ Sbjct: 63 IICL 66 >6ACF-A nrPDB Length = 367 Score = 37.3 bits (85), Expect = 0.010, Method: Composition-based stats. Identities = 20/109 (18%), Positives = 39/109 (35%), Gaps = 10/109 (9%) Query: 136 GGWTSWKPLWLCGYG---LTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYT-GRQPRPEE 191 G + K +G L V + G+G + + R L G + + ++ Sbjct: 153 GVYRGMKAAAKEAFGSDSLEGKVVAVQGVGNVAYHLCRHLHEEGAKLIVTDINKEAVARA 212 Query: 192 AAEFQAEFVSTPELAA-QSDFIVVACSLTPATEGLCNKDFFQKMKETAV 239 EF A+ V ++ + D C+L G+ N ++K + Sbjct: 213 VEEFGAKAVDPNDIYGVECDIFAP-CAL----GGIINDQTIPQLKAKVI 256 >2F1K-A nrPDB Length = 279 Score = 37.3 bits (85), Expect = 0.010, Method: Composition-based stats. Identities = 20/95 (21%), Positives = 39/95 (41%), Gaps = 8/95 (8%) Query: 154 STVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPE--LAAQSDF 211 +G++GLG IG ++A L+ G + +Q E+A E Q + + L + Sbjct: 1 MKIGVVGLGLIGASLAGDLRRRGHYLIGVSRQQSTCEKAVERQLVDEAGQDLSLLQTAKI 60 Query: 212 IVVACS--LTPATEGLCNKDFFQKMKETAVFINIS 244 I + L T + + TA+ +++ Sbjct: 61 IFLCTPIQLILPTL----EKLIPHLSPTAIVTDVA 91 >1GTM-A nrPDB Length = 419 Score = 36.9 bits (84), Expect = 0.011, Method: Composition-based stats. Identities = 13/84 (15%), Positives = 32/84 (38%), Gaps = 7/84 (8%) Query: 126 LPEAIEEVKNGGWTSWKPLWLCGYG-LTQSTVGIIGLGRIGQAIARRL-KPFGVQRFLYT 183 L + +T + + G+ L T+ I G G G +A+ + + FG++ + Sbjct: 184 LGRIEATARGASYTIREAAKVLGWDTLKGKTIAIQGYGNAGYYLAKIMSEDFGMKVVAVS 243 Query: 184 GRQPRPEEAAEFQAEFVSTPELAA 207 + + + ++ E+ Sbjct: 244 D-----SKGGIYNPDGLNADEVLK 262 >3VPX-A nrPDB Length = 364 Score = 36.5 bits (83), Expect = 0.014, Method: Composition-based stats. Identities = 19/92 (20%), Positives = 37/92 (40%), Gaps = 7/92 (7%) Query: 150 GLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAE-FQAEFVSTPELAAQ 208 L TV + G+G + A+ L G + + + + A + F A V E+ +Q Sbjct: 170 SLAGKTVAVQGVGNVAYALCEYLHEEGAKLIITDINEEAVQRAVDAFGATAVGINEIYSQ 229 Query: 209 -SDFIVVACSLTPATEGLCNKDFFQKMKETAV 239 +D C+L + N + ++K + Sbjct: 230 EADIFAP-CALGA----IINDETIPQLKAKVI 256 >4D3F-A nrPDB Length = 310 Score = 36.5 bits (83), Expect = 0.016, Method: Composition-based stats. Identities = 21/97 (21%), Positives = 43/97 (44%), Gaps = 9/97 (9%) Query: 152 TQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVST-PELAAQSD 210 + +V +IGLG +GQA+A +G ++ + ++ A VST E A ++ Sbjct: 20 NRKSVTVIGLGPMGQAMADVFLEYGYSVTVWNRTSSKADQLVAKGAIRVSTVNEALAANE 79 Query: 211 FIVVACSLTPATEGLCNKDFFQKMKE---TAVFINIS 244 ++++ T+ + + E V +N+S Sbjct: 80 LVILSL-----TDYNVMYSILEPVSENLFGKVLVNLS 111 >2PV7-A nrPDB Length = 298 Score = 36.5 bits (83), Expect = 0.018, Method: Composition-based stats. Identities = 12/83 (14%), Positives = 28/83 (33%), Gaps = 18/83 (21%) Query: 154 STVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIV 213 V + G G++G AR L+ G + + + A +D ++ Sbjct: 23 KIVIVGGYGKLGGLFARYLRASGYPISILDRED------------WAVAESILANADVVI 70 Query: 214 VACSLTPATEGLCNKDFFQKMKE 236 V+ + + +++K Sbjct: 71 VSVPIN------LTLETIERLKP 87 >6HD1-C nrPDB Length = 459 Score = 36.1 bits (82), Expect = 0.023, Method: Composition-based stats. Identities = 22/102 (21%), Positives = 40/102 (39%), Gaps = 6/102 (5%) Query: 143 PLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVST 202 PL + Q TV I G G G+++ ++ G + R P+ AE +S Sbjct: 10 PLTMNSSE-KQETVCIFGTGDFGRSLGLKMLQCGYSVVFGS-RNPQKTTLLPSGAEVLSY 67 Query: 203 PELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINIS 244 E A +S I++A + ++ + ++IS Sbjct: 68 SEAAKKSGIIIIAI--HREHYDFLTE--LTEVLNGKILVDIS 105 >3ABT-A nrPDB Length = 662 Score = 36.1 bits (82), Expect = 0.023, Method: Composition-based stats. Identities = 17/66 (25%), Positives = 26/66 (39%), Gaps = 1/66 (1%) Query: 122 TCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFL 181 R+ +E + +K + T + IIG G G A AR+L+ FG+ L Sbjct: 77 LVHRVHSYLERHGLINFGIYKRIKPLPTKKTGKVI-IIGSGVSGLAAARQLQSFGMDVTL 135 Query: 182 YTGRQP 187 R Sbjct: 136 LEARDR 141 >5L3D-A nrPDB Length = 852 Score = 35.7 bits (81), Expect = 0.030, Method: Composition-based stats. Identities = 17/66 (25%), Positives = 26/66 (39%), Gaps = 1/66 (1%) Query: 122 TCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFL 181 R+ +E + +K + T + IIG G G A AR+L+ FG+ L Sbjct: 248 LVHRVHSYLERHGLINFGIYKRIKPLPTKKTGKVI-IIGSGVSGLAAARQLQSFGMDVTL 306 Query: 182 YTGRQP 187 R Sbjct: 307 LEARDR 312 >4RG3-A nrPDB Length = 548 Score = 35.7 bits (81), Expect = 0.031, Method: Composition-based stats. Identities = 17/72 (23%), Positives = 28/72 (38%), Gaps = 4/72 (5%) Query: 141 WKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFV 200 W G L VG+IG G GQ + L P + T P+ + V Sbjct: 174 HTAAWPEGKSLAGRRVGVIGTGSTGQQVITSLAP---EVEHLTVFVRTPQYSVPVGNRPV 230 Query: 201 STPELAA-QSDF 211 + ++A ++D+ Sbjct: 231 NPEQIAEIKADY 242 >1NPD-A nrPDB Length = 288 Score = 35.3 bits (80), Expect = 0.038, Method: Composition-based stats. Identities = 40/287 (13%), Positives = 78/287 (27%), Gaps = 63/287 (21%) Query: 31 VEQWDSDEPIPAKELERGVAGAHGLLCLLSDHVDKRILDAAGANLKVISTMSVGIDHLAL 90 + + + + + + A ++ VD A LK + G+ Sbjct: 12 LMAYPIRHSLSPEMQNKALEKAGLPFTYMAFEVDNDSFPGAIEGLKALKMRGTGVSMPNK 71 Query: 91 DEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNG----GWTSWKPLWL 146 + EL + L + G G + + Sbjct: 72 QLACEY--------------VDELTPAAKLVGAINTIVNDDGYLRGYNTDGTGHIRAIKE 117 Query: 147 CGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELA 206 G+ + T+ ++G G AI + G++ R+ + A A+ V+ Sbjct: 118 SGFDIKGKTMVLLGAGGASTAIGAQGAIEGLKEIKLFNRRDEFFDKALAFAQRVN----- 172 Query: 207 AQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAA 266 +D +V D+ +Q +ALAS I Sbjct: 173 ENTDCVVTVT------------------------------DLADQQAFAEALASADILTN 202 Query: 267 GLDV----TSPEPLPTNHPLLTLKNCVIL-----PHIGSATHRTRNT 304 G V E L + LL ++ PH+ + + Sbjct: 203 GTKVGMKPLENESLVNDISLL-HPGLLVTECVYNPHMTKLLQQAQQA 248 >3AOE-E nrPDB Length = 419 Score = 35.3 bits (80), Expect = 0.039, Method: Composition-based stats. Identities = 10/34 (29%), Positives = 18/34 (52%) Query: 148 GYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFL 181 G L + V + GLG++G A+A + G++ Sbjct: 213 GLDLRGARVVVQGLGQVGAAVALHAERLGMRVVA 246 >6ER9-A nrPDB Length = 549 Score = 35.3 bits (80), Expect = 0.040, Method: Composition-based stats. Identities = 12/34 (35%), Positives = 14/34 (41%) Query: 141 WKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKP 174 W G L VG+IG G GQ + L P Sbjct: 167 HTAAWPEGKNLAGKRVGVIGTGSTGQQVITALAP 200 >3UP5-A nrPDB Length = 545 Score = 34.9 bits (79), Expect = 0.042, Method: Composition-based stats. Identities = 11/43 (25%), Positives = 14/43 (32%) Query: 131 EEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLK 173 E + W + G T VG+IG G G I Sbjct: 163 ESFHSSRWPTDAEGAPKGVDFTGKRVGVIGTGATGVQIIPIAA 205 >5XVH-A nrPDB Length = 306 Score = 34.9 bits (79), Expect = 0.048, Method: Composition-based stats. Identities = 22/94 (23%), Positives = 39/94 (41%), Gaps = 3/94 (3%) Query: 154 STVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEF-VSTPELAAQSDFI 212 VG IGLG +G +A L G +Y + + + AE S +LA + D + Sbjct: 21 MRVGFIGLGIMGGPMATHLLKAGFLAAVYNRTREKTKPFAEAGVYVAESPADLAKRVDVV 80 Query: 213 VVACSLTPATEGLC--NKDFFQKMKETAVFINIS 244 +V S P E + + + + +++S Sbjct: 81 IVMVSDAPDVEQVLFGPSGVVEGARPGLIVVDMS 114 >3DZB-A nrPDB Length = 317 Score = 34.9 bits (79), Expect = 0.051, Method: Composition-based stats. Identities = 22/101 (21%), Positives = 39/101 (38%), Gaps = 8/101 (7%) Query: 150 GLTQSTVGIIGLGRIGQAIA---RRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVST---P 203 L++ T+ I GLG IG ++A +R P + Y A E +T Sbjct: 2 SLSKKTIYIAGLGLIGGSLALGIKRDHP-DYEILGYNRSDYSRNIALERGIVDRATGDFK 60 Query: 204 ELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINIS 244 E A +D I++A + T + +K+ + + Sbjct: 61 EFAPLADVIILAVPI-KQTMAYLKELADLDLKDNVIITDAG 100 >2RCY-A nrPDB Length = 262 Score = 34.9 bits (79), Expect = 0.054, Method: Composition-based stats. Identities = 19/70 (27%), Positives = 29/70 (41%), Gaps = 7/70 (10%) Query: 150 GLTQSTVGIIGLGRIGQAIAR-RLKPFGVQR--FLYTGRQPRPEEAAEFQAEFVSTPELA 206 G+ +G +GLG++G A+A +++ Y G P + S ELA Sbjct: 1 GMENIKLGFMGLGQMGSALAHGIANANIIKKENLFYYG----PSKKNTTLNYMSSNEELA 56 Query: 207 AQSDFIVVAC 216 D IV A Sbjct: 57 RHCDIIVCAV 66 >5Y8M-A nrPDB Length = 295 Score = 34.6 bits (78), Expect = 0.055, Method: Composition-based stats. Identities = 24/108 (22%), Positives = 41/108 (37%), Gaps = 2/108 (1%) Query: 155 TVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAA-EFQAEFVSTPELAAQSDFIV 213 T+ +GLG +G ++ L G + AA A F S PE A++D ++ Sbjct: 4 TIAFLGLGNMGAPMSANLVGAGHVVRGFDPAPTAASGAAAHGVAVFRSAPEAVAEADVVI 63 Query: 214 VACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASG 261 T C D + +FI+ S V + +++ S Sbjct: 64 TMLP-TGEVVRRCYTDVLAAARPATLFIDSSTISVTDAREVHALAESH 110 >6F3O-A nrPDB Length = 472 Score = 34.6 bits (78), Expect = 0.061, Method: Composition-based stats. Identities = 22/108 (20%), Positives = 39/108 (36%), Gaps = 18/108 (16%) Query: 151 LTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVST-------- 202 L+ +IG G +G+ ++ L+ G+ + +A E VS Sbjct: 222 LSGKQALVIGYGDVGKGSSQSLRQEGMIVKVAEVDPICAMQACMDGFEVVSPYKNGINDG 281 Query: 203 ------PELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINIS 244 L + D IV T +C+ + + +K+ AV NI Sbjct: 282 TEASIDAALLGKIDLIVT----TTGNVNVCDANMLKALKKRAVVCNIG 325 >3PII-A nrPDB Length = 339 Score = 34.6 bits (78), Expect = 0.071, Method: Composition-based stats. Identities = 12/48 (25%), Positives = 17/48 (35%) Query: 153 QSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFV 200 V I G+G G + K G+ + E A E A+ V Sbjct: 165 GEWVAIYGIGGFGHVAVQYAKAMGLNVVAVDIGDEKLELAKELGADLV 212 >6IQV-A nrPDB Length = 340 Score = 34.2 bits (77), Expect = 0.081, Method: Composition-based stats. Identities = 19/88 (21%), Positives = 31/88 (35%), Gaps = 19/88 (21%) Query: 155 TVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVV 214 +GI G GRIG+ RR+ G E V+ +L S ++ Sbjct: 4 KIGINGFGRIGRLAFRRILELG---------------EKSSDIEVVAINDL--TSPALLA 46 Query: 215 ACSLTPATEGLCNKDFFQKMKETAVFIN 242 +T G N D + ++ +N Sbjct: 47 HLLKYDSTHGTLNADVSAT--DDSIVVN 72 >4PZE-A nrPDB Length = 284 Score = 34.2 bits (77), Expect = 0.083, Method: Composition-based stats. Identities = 13/55 (23%), Positives = 21/55 (38%), Gaps = 2/55 (3%) Query: 154 STVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQ 208 TVGI+G G +G IA+ G+ + ++ A S L + Sbjct: 4 RTVGIVGAGTMGNGIAQACAVVGLNVVMVDISDAAVQKGVATVAS--SLDRLIKK 56 >3H9E-O nrPDB Length = 346 Score = 34.2 bits (77), Expect = 0.083, Method: Composition-based stats. Identities = 14/40 (35%), Positives = 18/40 (45%) Query: 151 LTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPE 190 + TVGI G GRIG+ + R GV+ PE Sbjct: 5 ARELTVGINGFGRIGRLVLRACMEKGVKVVAVNDPFIDPE 44 >2CZC-A nrPDB Length = 334 Score = 34.2 bits (77), Expect = 0.088, Method: Composition-based stats. Identities = 17/86 (19%), Positives = 26/86 (30%), Gaps = 24/86 (27%) Query: 155 TVGIIGLGRIGQAI-----------------------ARRLKPFGVQRFLYTGRQPRPEE 191 VG+ G G IG+ + A R K G+ + + P Sbjct: 4 KVGVNGYGTIGKRVAYAVTKQDDMELIGITKTKPDFEAYRAKELGIPVYA-ASEEFIPRF 62 Query: 192 AAEFQAEFVSTPELAAQSDFIVVACS 217 E + +L + D IV A Sbjct: 63 EKEGFEVAGTLNDLLEKVDIIVDATP 88 >3F9I-A nrPDB Length = 249 Score = 33.8 bits (76), Expect = 0.095, Method: Composition-based stats. Identities = 27/132 (20%), Positives = 41/132 (31%), Gaps = 37/132 (28%) Query: 150 GLTQSTVGIIGLGR-IGQAIARRLKPFGVQRFLYTGRQPRPEE-----------AAEFQA 197 LT T I G IG AIAR L G + + + + + A Sbjct: 11 DLTGKTSLITGASSGIGSAIARLLHKLGSKVIISGSNEEKLKSLGNALKDNYTIEVCNLA 70 Query: 198 EFVSTPELAAQS---DFIVVACSLTPATEG--------------------LCNKDFFQKM 234 L +++ D +V +T T + N++ +KM Sbjct: 71 NKEECSNLISKTSNLDILVCNAGITSDTLAIRMKDQDFDKVIDINLKANFILNREAIKKM 130 Query: 235 --KETAVFINIS 244 K INIS Sbjct: 131 IQKRYGRIINIS 142 >4DIO-A nrPDB Length = 405 Score = 33.8 bits (76), Expect = 0.098, Method: Composition-based stats. Identities = 21/143 (14%), Positives = 42/143 (29%), Gaps = 37/143 (25%) Query: 158 IIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPEL------------ 205 ++G G G + G R E+ A A+F++ + Sbjct: 195 VMGAGVAGLQAIATARRLGAVVSATDVRPAAKEQVASLGAKFIAVEDEEFKAAETAGGYA 254 Query: 206 ------------------AAQSDFI--VVACSLTPATEGLCNKDFFQKMKETAVFINISR 245 A+ D + PA L ++ MK +V ++++ Sbjct: 255 KEMSGEYQVKQAALVAEHIAKQDIVITTALIPGRPAPR-LVTREMLDSMKPGSVVVDLA- 312 Query: 246 GDVVNQDDLYQALASGKIAAAGL 268 V + + +GK+ G Sbjct: 313 ---VERGGNIEGAEAGKVTEVGG 332 >3IHM-A nrPDB Length = 430 Score = 33.8 bits (76), Expect = 0.099, Method: Composition-based stats. Identities = 11/39 (28%), Positives = 17/39 (43%) Query: 154 STVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEA 192 +GI+G G G + L+ V +YT R+P Sbjct: 23 KRIGIVGAGTAGLHLGLFLRQHDVDVTVYTDRKPDEYSG 61 >4E21-A nrPDB Length = 358 Score = 33.8 bits (76), Expect = 0.11, Method: Composition-based stats. Identities = 16/68 (23%), Positives = 27/68 (39%), Gaps = 4/68 (5%) Query: 154 STVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEE-AAEFQAEFVSTPEL---AAQS 209 +G+IGLGR+G + RRL+ G + +Y + E A S E + Sbjct: 23 MQIGMIGLGRMGADMVRRLRKGGHECVVYDLNVNAVQALEREGIAGARSIEEFCAKLVKP 82 Query: 210 DFIVVACS 217 + + Sbjct: 83 RVVWLMVP 90 >4OH1-A nrPDB Length = 351 Score = 33.8 bits (76), Expect = 0.12, Method: Composition-based stats. Identities = 15/117 (12%), Positives = 41/117 (35%), Gaps = 11/117 (9%) Query: 91 DEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYG 150 + ++ + + + +E AV + ++ ++ + +PL + Sbjct: 110 ENCREGKVNLCSNMGYRMNGFSEYAVYHM----SQIFPIPDDADLKDYALVEPLTVALSS 165 Query: 151 LT------QSTVGIIGLGRIGQAIARRLKPFGVQRF-LYTGRQPRPEEAAEFQAEFV 200 +V I+G G +G + + + G ++ + E A E A++ Sbjct: 166 AEQAKISYGKSVAIMGAGGLGMMLVQLARLAGASTITVFDIVPEKLELALENGADYA 222 >3ULK-A nrPDB Length = 491 Score = 33.8 bits (76), Expect = 0.12, Method: Composition-based stats. Identities = 19/123 (15%), Positives = 37/123 (30%), Gaps = 10/123 (8%) Query: 125 RLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTG 184 L + + ++ + L V I+G G G ++ G+ Y Sbjct: 9 NLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVGCGAQGLNQGLNMRDSGLD-ISYAL 67 Query: 185 R-------QPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKET 237 R + +A E + + EL Q+D ++ + MK+ Sbjct: 68 RKEAIAEKRASWRKATENGFKVGTYEELIPQADLVINLTP--DKQHSDVVRTVQPLMKDG 125 Query: 238 AVF 240 A Sbjct: 126 AAL 128 >3UF0-A nrPDB Length = 273 Score = 33.8 bits (76), Expect = 0.12, Method: Composition-based stats. Identities = 23/118 (19%), Positives = 33/118 (27%), Gaps = 16/118 (13%) Query: 136 GGWTSWKPLWLCGYGLTQSTVGIIGLGR-IGQAIARRLKPFGVQRFLYTGRQPRPEEAAE 194 G + + L T + G G IG+AIA G + E A E Sbjct: 14 GTENLYFQSMTGPFSLAGRTAVVTGAGSGIGRAIAHGYARAGAHVLAWGRTDGVKEVADE 73 Query: 195 FQAEFVSTPELAAQSDFIVVACSLTPATEGLCN-KDFFQKMKETAVFIN----ISRGD 247 S + A EG N + + V +N I+R Sbjct: 74 IADGGGSAEAVVAD----------LADLEGAANVAEELAATRRVDVLVNNAGIIARAP 121 >1CRW-G nrPDB Length = 333 Score = 33.4 bits (75), Expect = 0.14, Method: Composition-based stats. Identities = 17/87 (19%), Positives = 29/87 (33%), Gaps = 23/87 (26%) Query: 155 TVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVV 214 +GI G GRIG+ + R G Q P A E+ + Sbjct: 2 KIGINGFGRIGRLVLRAALEMGAQVVA----VNDPFIALEYMVY------MFK------- 44 Query: 215 ACSLTPATEGLCNKDFFQKMKETAVFI 241 +T G+ + K ++ A+ + Sbjct: 45 ----YDSTHGMFKGEV--KAEDGALVV 65 >4DLA-A nrPDB Length = 396 Score = 33.4 bits (75), Expect = 0.14, Method: Composition-based stats. Identities = 15/62 (24%), Positives = 23/62 (37%) Query: 136 GGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEF 195 G T +W S V + GLG +G A+A K G R + + + A+ Sbjct: 195 GVPTGLGAVWNTAKVEPGSIVAVFGLGTVGLAVAEGAKAAGASRIIGIDIDSKKFDRAKN 254 Query: 196 QA 197 Sbjct: 255 FG 256 >5T57-A nrPDB Length = 296 Score = 33.4 bits (75), Expect = 0.16, Method: Composition-based stats. Identities = 14/89 (15%), Positives = 29/89 (32%), Gaps = 4/89 (4%) Query: 154 STVGIIGLG-RIGQAIARRLKPFGVQRFLY-TGRQPRPEEAAEFQAEFVSTPELAAQSDF 211 + + G G ++G +A+ L + + E E VST D Sbjct: 23 EKIALFGAGGKMGVRLAKNLLKSDYRVSHVEVSEVGKKRLKDELGLECVSTEAALDNVDV 82 Query: 212 IVVACSLTPATEGLCNKDFFQKMKETAVF 240 +++A T G +++ + Sbjct: 83 VILAVPDT--IIGKIAAQIAPQLRPGTMV 109 >5C7I-O nrPDB Length = 333 Score = 33.0 bits (74), Expect = 0.17, Method: Composition-based stats. Identities = 13/38 (34%), Positives = 18/38 (47%) Query: 153 QSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPE 190 + TVGI G GRIG+ + R G++ PE Sbjct: 1 ELTVGINGFGRIGRLVLRVCMEKGIRVVAVNDPFIDPE 38 >6N7L-A nrPDB Length = 353 Score = 33.0 bits (74), Expect = 0.19, Method: Composition-based stats. Identities = 10/48 (20%), Positives = 17/48 (35%) Query: 153 QSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFV 200 V I G+G +G + K G+ + E A + A+ Sbjct: 177 GEWVAISGIGGLGHVAVQYAKAMGMHVAAIDVADDKLELAKKLGADLT 224 >5VDN-A nrPDB Length = 463 Score = 33.0 bits (74), Expect = 0.20, Method: Composition-based stats. Identities = 27/170 (15%), Positives = 51/170 (30%), Gaps = 16/170 (9%) Query: 40 IPAKELERGVAGAHGLLCLLSDHVDKRILDAAGANLKVISTMSVGIDHLALDEIKKRGIR 99 +P K + A + D+ ++ K+I+ + ID + +RG Sbjct: 61 VPKKVMWHAAQIAEAIHLYGPDYGFDTTVNHFDWK-KLIANRTAYIDRIHQSY--ERG-- 115 Query: 100 VGYTPDVLTDTTAELAVSLLLTTC-RRLPEAIEEVKNGGWTSWKPLWLCGYGLTQ----- 153 +G + A + + + + GG S + YG+ Sbjct: 116 LGNNKVDVIQGFARFVDAHTVEVNGETITADHILIATGGRPSHPDIPGAEYGIDSDGFFE 175 Query: 154 -----STVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAE 198 V ++G G I IA L G + L+ + E Sbjct: 176 LDEMPKRVAVVGAGYIAVEIAGVLNGLGTETHLFVRKHAPLRTFDPLIVE 225 >1YB4-A nrPDB Length = 295 Score = 33.0 bits (74), Expect = 0.20, Method: Composition-based stats. Identities = 16/68 (23%), Positives = 26/68 (38%) Query: 154 STVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIV 213 +G IGLG +G +A L G Q + T E + + ++ +D I Sbjct: 4 MKLGFIGLGIMGSPMAINLARAGHQLHVTTIGPVADELLSLGAVNVETARQVTEFADIIF 63 Query: 214 VACSLTPA 221 + TP Sbjct: 64 IMVPDTPQ 71 >3BIO-A nrPDB Length = 304 Score = 32.6 bits (73), Expect = 0.22, Method: Composition-based stats. Identities = 23/120 (19%), Positives = 34/120 (28%), Gaps = 17/120 (14%) Query: 155 TVGIIGLGRIGQAIARRL-KPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIV 213 I+G G IG+ + L + + R P VS E D + Sbjct: 11 RAAIVGYGNIGRYALQALREAPDFEIAGIVRRNPAEVPFELQPFRVVSDIEQLESVDVAL 70 Query: 214 VACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALAS------GKIAAAG 267 V + + +K+ I D + D AL GK AA Sbjct: 71 VCSPSRE-----VERTALEILKKG-----ICTADSFDIHDGILALRRSLGDAAGKSGAAA 120 >3MOG-A nrPDB Length = 483 Score = 32.6 bits (73), Expect = 0.24, Method: Composition-based stats. Identities = 25/110 (22%), Positives = 33/110 (30%), Gaps = 28/110 (25%) Query: 150 GLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQS 209 L TV +IG G +G IA G Q LY +S L Sbjct: 2 SLNVQTVAVIGSGTMGAGIAEVAASHGHQVLLYD----------------ISAEALTRAI 45 Query: 210 DFIVVACSLTPA-TEGLCNKDFFQK-MKETAVFINISRGDVVNQDDLYQA 257 D I L T G + ++ +K I V + L A Sbjct: 46 DGI--HARLNSRVTRGKLTAETCERTLKR---LI-----PVTDIHALAAA 85 >6B4O-A nrPDB Length = 452 Score = 32.6 bits (73), Expect = 0.25, Method: Composition-based stats. Identities = 18/106 (16%), Positives = 29/106 (27%), Gaps = 6/106 (5%) Query: 154 STVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQS-DFI 212 V +G G I +A L G + + R RP + + Sbjct: 170 KRVVFVGAGYIAAELAGTLHGLGAET-HWAFRHERPLRSFDDMLSEKVVERYQEMGMQIH 228 Query: 213 VVACSL----TPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDL 254 A T E + + + + AV R +Q L Sbjct: 229 PNATPAKIEKTAQNEYVITFENGESITTDAVIFGTGRQPNTDQLGL 274 >4G65-A nrPDB Length = 461 Score = 32.6 bits (73), Expect = 0.26, Method: Composition-based stats. Identities = 25/106 (23%), Positives = 43/106 (40%), Gaps = 10/106 (9%) Query: 154 STVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEF------QAEFVSTPELAA 207 + I+G G IG ++A+RL+ L R E+ +E + EL Sbjct: 236 RRIMIVGGGNIGASLAKRLEQ-TYSVKLIERNLQRAEKLSEELENTIVFCGDAADQELLT 294 Query: 208 QS--DFIVVACSLTPATE-GLCNKDFFQKMKETAVFINISRGDVVN 250 + D + V +LT E + + ++M V + I RG V+ Sbjct: 295 EENIDQVDVFIALTNEDETNIMSAMLAKRMGAKKVMVLIQRGAYVD 340 >3FBG-A nrPDB Length = 346 Score = 32.2 bits (72), Expect = 0.29, Method: Composition-based stats. Identities = 12/50 (24%), Positives = 20/50 (40%), Gaps = 1/50 (2%) Query: 152 TQSTVGII-GLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFV 200 T+ II G G +G + K +G++ R E + A+ V Sbjct: 150 EGKTLLIINGAGGVGSIATQIAKAYGLRVITTASRNETIEWTKKMGADIV 199 >1CF2-P nrPDB Length = 337 Score = 32.2 bits (72), Expect = 0.29, Method: Composition-based stats. Identities = 9/109 (8%), Positives = 32/109 (29%), Gaps = 24/109 (22%) Query: 154 STVGIIGLGRIGQAIAR-RLKPFGVQRFLYTGRQPRPEEAAEFQAEFV------------ 200 V I G G +G+ +A + ++ + +P E + + Sbjct: 2 KAVAINGYGTVGKRVADAIAQQDDMKVIGVSKTRPDFEARMALKKGYDLYVAIPERVKLF 61 Query: 201 ---------STPELAAQSDFIVVACS--LTPATEGLCNKDFFQKMKETA 238 + ++ ++D ++ + + + + + + Sbjct: 62 EKAGIEVAGTVDDMLDEADIVIDCTPEGIGAKNLKMYKEKGIKAIFQGG 110 >3UVE-A nrPDB Length = 286 Score = 32.2 bits (72), Expect = 0.29, Method: Composition-based stats. Identities = 20/121 (16%), Positives = 35/121 (28%), Gaps = 24/121 (19%) Query: 142 KPLWLCGYGLTQSTVGIIGLGR-IGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFV 200 P + G + + G R G++ A RL G +P + Sbjct: 1 GPGSMTGR-VEGKVAFVTGAARGQGRSHAVRLAQEGADIIAVDICKPIRAGVVDTAIPAS 59 Query: 201 STPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALAS 260 + +LA +D + + + DV + D L A+ S Sbjct: 60 TPEDLAETADLVKGH------NRRIVTAEV----------------DVRDYDALKAAVDS 97 Query: 261 G 261 G Sbjct: 98 G 98 Score = 28.8 bits (63), Expect = 3.6, Method: Composition-based stats. Identities = 15/54 (27%), Positives = 25/54 (46%), Gaps = 3/54 (5%) Query: 84 GIDHLALDEIK--KRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKN 135 G D +A+D K + G+ P + AE A L+ RR+ A +V++ Sbjct: 35 GADIIAVDICKPIRAGVVDTAIPASTPEDLAETA-DLVKGHNRRIVTAEVDVRD 87 >1EZ1-A nrPDB Length = 392 Score = 32.2 bits (72), Expect = 0.30, Method: Composition-based stats. Identities = 14/102 (13%), Positives = 34/102 (33%), Gaps = 2/102 (1%) Query: 147 CGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELA 206 + V ++G G +G+ +A + GV+ P ++ ++ + Sbjct: 6 TALRPAATRVMLLGSGELGKEVAIECQRLGVEVIAVDRYADAPAMHVAHRSHVINMLDGD 65 Query: 207 AQSDFIVVACS--LTPATEGLCNKDFFQKMKETAVFINISRG 246 A + + + P E + Q +E + +R Sbjct: 66 ALRRVVELEKPHYIVPEIEAIATDMLIQLEEEGLNVVPCARA 107 >3PEF-A nrPDB Length = 287 Score = 32.2 bits (72), Expect = 0.30, Method: Composition-based stats. Identities = 18/64 (28%), Positives = 26/64 (40%), Gaps = 1/64 (1%) Query: 154 STVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTP-ELAAQSDFI 212 G IGLG +G A+A+ L G ++ + EE A AE +TP E+ Sbjct: 2 QKFGFIGLGIMGSAMAKNLVKAGCSVTIWNRSPEKAEELAALGAERAATPCEVVESCPVT 61 Query: 213 VVAC 216 Sbjct: 62 FAML 65 >3DOJ-A nrPDB Length = 310 Score = 32.2 bits (72), Expect = 0.30, Method: Composition-based stats. Identities = 16/66 (24%), Positives = 28/66 (42%), Gaps = 1/66 (1%) Query: 145 WLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEF-VSTP 203 L G VG +GLG +G+A++ L G + ++ + +E E A S Sbjct: 13 GLVPRGSHMMEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPA 72 Query: 204 ELAAQS 209 E+ + Sbjct: 73 EVIKKC 78 >4K28-A nrPDB Length = 269 Score = 32.2 bits (72), Expect = 0.31, Method: Composition-based stats. Identities = 21/131 (16%), Positives = 35/131 (26%), Gaps = 22/131 (16%) Query: 148 GYGLTQSTVGIIGLGRIGQAIARRLKPFG-VQRFLYTGRQPRPEEAAEFQA--------- 197 G+ +IG G +G AIA L G L R E Sbjct: 120 GFEPAGKRALVIGCGGVGSAIAYALAEAGIASITLCDPSTARMGAVCELLGNGFPGLTVS 179 Query: 198 -EFVSTPELAAQSDFIVVACSLTPATEGL--CNKDFFQKMKETAVFINISRGDVVNQDDL 254 +F + D + A + T + ++ + DVV ++ Sbjct: 180 TQFSGLEDF----DLVANASPVGMGTRAELPLSAALLATLQPDTLV-----ADVVTSPEI 230 Query: 255 YQALASGKIAA 265 L + Sbjct: 231 TPLLNRARQVG 241 >2HK7-A nrPDB Length = 269 Score = 32.2 bits (72), Expect = 0.32, Method: Composition-based stats. Identities = 19/88 (21%), Positives = 38/88 (43%), Gaps = 4/88 (4%) Query: 150 GLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEE-AAEFQAEFV-STPELAA 207 + + ++ ++G G +A+ L G + FL+ + + + A +F E V S E+ Sbjct: 120 EVKEKSILVLGAGGASRAVIYALVKEGAKVFLWNRTKEKAIKLAQKFPLEVVNSPEEVID 179 Query: 208 QSDFIVV--ACSLTPATEGLCNKDFFQK 233 + IV + L + N D +K Sbjct: 180 KVQVIVNTTSVGLKDEDPEIFNYDLIKK 207 >1E3J-A nrPDB Length = 352 Score = 32.2 bits (72), Expect = 0.32, Method: Composition-based stats. Identities = 13/48 (27%), Positives = 17/48 (35%) Query: 153 QSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFV 200 +TV +IG G IG K +G R E A A+ Sbjct: 169 GTTVLVIGAGPIGLVSVLAAKAYGAFVVCTARSPRRLEVAKNCGADVT 216 >4JJI-A nrPDB Length = 378 Score = 32.2 bits (72), Expect = 0.33, Method: Composition-based stats. Identities = 20/71 (28%), Positives = 28/71 (39%), Gaps = 2/71 (2%) Query: 136 GGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGV-QRFLYTGRQPRPEEAAE 194 G T +W S V I GLG +G A+A K G + + E A + Sbjct: 177 GVPTGLGAVWNTAKVEPGSNVAIFGLGTVGLAVAEGAKTAGASRIIGIDIDSKKYETAKK 236 Query: 195 FQA-EFVSTPE 204 F EFV+ + Sbjct: 237 FGVNEFVNPKD 247 >1BG6-A nrPDB Length = 359 Score = 31.9 bits (71), Expect = 0.36, Method: Composition-based stats. Identities = 16/83 (19%), Positives = 26/83 (31%), Gaps = 16/83 (19%) Query: 151 LTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEE--------AAEFQAEFVST 202 + T ++GLG G A A L G + R +E A + Sbjct: 2 IESKTYAVLGLGNGGHAFAAYLALKGQSVLAWDIDAQRIKEIQDRGAIIAEGPGLAGTAH 61 Query: 203 PELA--------AQSDFIVVACS 217 P+L +D I++ Sbjct: 62 PDLLTSDIGLAVKDADVILIVVP 84 >1XLT-A nrPDB Length = 384 Score = 31.9 bits (71), Expect = 0.36, Method: Composition-based stats. Identities = 18/122 (14%), Positives = 33/122 (27%), Gaps = 33/122 (27%) Query: 155 TVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPE---------- 204 V + G+G G K G R E+ +F++ + Sbjct: 174 RVLVFGVGVAGLQAIATAKRLGAVVMATDVRAATKEQVESLGGKFITVDDEAMKTAETAG 233 Query: 205 --------------------LAAQSD--FIVVACSLTPATEGLCNKDFFQKMKETAVFIN 242 ++D PA L ++ KMK +V I+ Sbjct: 234 GYAKEMGEEFRKKQAEAVLKELVKTDIAITTALIPGKPAPV-LITEEMVTKMKPGSVIID 292 Query: 243 IS 244 ++ Sbjct: 293 LA 294 >3F3S-A nrPDB Length = 313 Score = 31.9 bits (71), Expect = 0.37, Method: Composition-based stats. Identities = 14/47 (29%), Positives = 20/47 (42%) Query: 158 IIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPE 204 I+G G IG++ A G Q LY Q + A E + + E Sbjct: 8 IVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLE 54 >1ZCJ-A nrPDB Length = 463 Score = 31.9 bits (71), Expect = 0.39, Method: Composition-based stats. Identities = 19/112 (16%), Positives = 35/112 (31%), Gaps = 23/112 (20%) Query: 156 VGIIGLGRIGQAIARRLKPFGVQRFLY----------------------TGRQPRPEEAA 193 VG++GLG +G+ IA G+ + + +A Sbjct: 40 VGVLGLGTMGRGIAISFARVGISVVAVESDPKQLDAAKKIITFTLEKEASRAHQNGQASA 99 Query: 194 EFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFI-NIS 244 + + F S+ + + D +V A + + K A N S Sbjct: 100 KPKLRFSSSTKELSTVDLVVEAVFEDMNLKKKVFAELSALCKPGAFLCTNTS 151 >1CER-O nrPDB Length = 331 Score = 31.9 bits (71), Expect = 0.39, Method: Composition-based stats. Identities = 12/26 (46%), Positives = 15/26 (57%) Query: 154 STVGIIGLGRIGQAIARRLKPFGVQR 179 VGI G GRIG+ + R L GV+ Sbjct: 1 MKVGINGFGRIGRQVFRILHSRGVEV 26 >6BZ0-A nrPDB Length = 480 Score = 31.9 bits (71), Expect = 0.41, Method: Composition-based stats. Identities = 8/40 (20%), Positives = 15/40 (37%) Query: 154 STVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAA 193 +G+IG G IG + + G + ++ A Sbjct: 184 KRLGVIGAGVIGLELGSVWRRLGAEVVVFEAMDAFLPMAD 223 >4DLL-A nrPDB Length = 320 Score = 31.9 bits (71), Expect = 0.41, Method: Composition-based stats. Identities = 26/140 (18%), Positives = 47/140 (33%), Gaps = 10/140 (7%) Query: 136 GGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEF 195 G + + +G G +G +ARRL G ++ R A Sbjct: 14 GTENLYFQSMTVESDPYARKITFLGTGSMGLPMARRLCEAGYALQVWNRTPARAASLAAL 73 Query: 196 QAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQK-----MKETAVFINISRGDVVN 250 A AA+ IVV+ + F + MK ++F++++ + Sbjct: 74 GATIHEQARAAARDADIVVS---MLENGAVVQDVLFAQGVAAAMKPGSLFLDMA--SITP 128 Query: 251 QDDLYQALASGKIAAAGLDV 270 ++ A G + A LD Sbjct: 129 REARDHAARLGALGIAHLDT 148 >4IZO-A nrPDB Length = 419 Score = 31.9 bits (71), Expect = 0.42, Method: Composition-based stats. Identities = 12/69 (17%), Positives = 26/69 (37%), Gaps = 6/69 (8%) Query: 151 LTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQA------EFVSTPE 204 L + +G++G G++G+ + G + + P A + + + E Sbjct: 33 LPGAWLGMVGGGQLGRMFCFAAQAMGYRVAVLDPDPTSPAGAVADKHLRAAYDDEAALAE 92 Query: 205 LAAQSDFIV 213 LA D + Sbjct: 93 LAQLCDAVS 101 >3ZWA-A nrPDB Length = 742 Score = 31.5 bits (70), Expect = 0.48, Method: Composition-based stats. Identities = 19/112 (16%), Positives = 35/112 (31%), Gaps = 23/112 (20%) Query: 156 VGIIGLGRIGQAIARRLKPFGVQRFLY----------------------TGRQPRPEEAA 193 VG++GLG +G+ IA G+ + + +A Sbjct: 319 VGVLGLGTMGRGIAISFARVGISVVAVESDPKQLDAAKKIITFTLEKEASRAHQNGQASA 378 Query: 194 EFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFI-NIS 244 + + F S+ + + D +V A + + K A N S Sbjct: 379 KPKLRFSSSTKELSTVDLVVEAVFEDMNLKKKVFAELSALCKPGAFLCTNTS 430 >3PDU-A nrPDB Length = 287 Score = 31.5 bits (70), Expect = 0.49, Method: Composition-based stats. Identities = 14/63 (22%), Positives = 22/63 (34%), Gaps = 1/63 (1%) Query: 155 TVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFV-STPELAAQSDFIV 213 T G +GLG +G +A L G ++ + A S E+ A D + Sbjct: 3 TYGFLGLGIMGGPMAANLVRAGFDVTVWNRNPAKCAPLVALGARQASSPAEVCAACDITI 62 Query: 214 VAC 216 Sbjct: 63 AML 65 >1JAY-A nrPDB Length = 212 Score = 31.5 bits (70), Expect = 0.49, Method: Composition-based stats. Identities = 17/101 (16%), Positives = 34/101 (33%), Gaps = 17/101 (16%) Query: 160 GLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVST--------PELAAQSDF 211 G G +G+ +A RL G + + + R+ + E A + A D Sbjct: 8 GTGNLGKGLALRLATLGHEIVVGSRREEKAEAKAAEYRRIAGDASITGMKNEDAAEACDI 67 Query: 212 IVVACSLTPATEGLCN-KDFFQKMKETAVFIN----ISRGD 247 V+ E + + + + ++ +SRG Sbjct: 68 AVLTIPW----EHAIDTARDLKNILREKIVVSPLVPVSRGA 104 >2O3A-A nrPDB Length = 178 Score = 31.5 bits (70), Expect = 0.50, Method: Composition-based stats. Identities = 12/63 (19%), Positives = 20/63 (31%), Gaps = 9/63 (14%) Query: 163 RIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEF---------VSTPELAAQSDFIV 213 RI +A + FG + + E+ E VS +L + D + Sbjct: 19 RISTHVALTARAFGAKGIYFDTEDKSVFESVRDVVERWGGDFFIKAVSWKKLLREFDGLK 78 Query: 214 VAC 216 V Sbjct: 79 VHL 81 >6DU7-A nrPDB Length = 448 Score = 31.5 bits (70), Expect = 0.51, Method: Composition-based stats. Identities = 13/45 (28%), Positives = 19/45 (42%) Query: 154 STVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAE 198 +V I+G G I +A L FGV+ L+ R + E Sbjct: 167 ESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVE 211 >3AOE-A nrPDB Length = 424 Score = 31.5 bits (70), Expect = 0.51, Method: Composition-based stats. Identities = 10/35 (28%), Positives = 14/35 (40%) Query: 147 CGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFL 181 G + + V I G G +G A AR G + Sbjct: 213 IGLQVEGARVAIQGFGNVGNAAARAFHDHGARVVA 247 >4XGI-A nrPDB Length = 436 Score = 31.5 bits (70), Expect = 0.56, Method: Composition-based stats. Identities = 6/34 (17%), Positives = 14/34 (41%) Query: 148 GYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFL 181 G + + + + G G +G A+ + G + Sbjct: 226 GVEIEGARIAVQGFGNVGGIAAKLFQEAGAKVIA 259 >2X41-A nrPDB Length = 721 Score = 31.5 bits (70), Expect = 0.57, Method: Composition-based stats. Identities = 11/36 (30%), Positives = 18/36 (50%), Gaps = 2/36 (5%) Query: 234 MKETAVFINISRGDVVNQDDLYQALASGKIAAAGLD 269 M A +N R D + + + +AL GK++ LD Sbjct: 261 MPGKAYQVNTERRDEIEE--IMEALKEGKLSEEVLD 294 >2R9Z-A nrPDB Length = 463 Score = 31.1 bits (69), Expect = 0.62, Method: Composition-based stats. Identities = 11/26 (42%), Positives = 14/26 (53%) Query: 154 STVGIIGLGRIGQAIARRLKPFGVQR 179 V IIG G IG +A L+ FG + Sbjct: 167 KRVAIIGAGYIGIELAGLLRSFGSEV 192 >2VYN-D nrPDB Length = 334 Score = 31.1 bits (69), Expect = 0.63, Method: Composition-based stats. Identities = 13/36 (36%), Positives = 16/36 (44%) Query: 155 TVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPE 190 VGI G GRIG+ + R GV+ PE Sbjct: 3 KVGINGFGRIGRLVLRVCMEKGVRVVAVNDPFIDPE 38 >4OM8-A nrPDB Length = 309 Score = 31.1 bits (69), Expect = 0.68, Method: Composition-based stats. Identities = 14/56 (25%), Positives = 22/56 (39%) Query: 154 STVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQS 209 + IIGLG +G +A RL G+Q Y E A + + + + Sbjct: 3 RNIAIIGLGTMGPGMAARLARGGLQVVAYDVAPAAIERARSMLSVAETVLDALGIA 58 >5OJG-A nrPDB Length = 260 Score = 31.1 bits (69), Expect = 0.70, Method: Composition-based stats. Identities = 19/79 (24%), Positives = 32/79 (40%), Gaps = 6/79 (7%) Query: 164 IGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLTPATE 223 IG AIA RL G + + Q +EA E+ + ++A I + T + Sbjct: 22 IGLAIAERLLDEGASVVIGSRNQKNVDEAIEY-LKNKGLTKVAG----IAGHIASTDDQK 76 Query: 224 GLCNKDFFQKMKETAVFIN 242 L + QK + + +N Sbjct: 77 KLVD-FTLQKFGKINILVN 94 >1H2H-A nrPDB Length = 241 Score = 31.1 bits (69), Expect = 0.72, Method: Composition-based stats. Identities = 16/68 (23%), Positives = 22/68 (32%), Gaps = 9/68 (13%) Query: 154 STVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIV 213 TV IIG+G IG+ + F + + Y V E SD Sbjct: 1 MTVLIIGMGNIGKKLVELGN-FE-KIYAYDRISKDI-------PGVVRLDEFQVPSDVST 51 Query: 214 VACSLTPA 221 V +P Sbjct: 52 VVECASPE 59 >1A5Z-A nrPDB Length = 319 Score = 31.1 bits (69), Expect = 0.72, Method: Composition-based stats. Identities = 18/101 (17%), Positives = 31/101 (30%), Gaps = 20/101 (19%) Query: 154 STVGIIGLGRIGQ--AIARRLKPF--GVQRFLYTGRQPRPEEAAEFQAE--------FVS 201 +GI+GLGR+G A A +K F + ++ + + Sbjct: 1 MKIGIVGLGRVGSSTAFALLMKGFAREMVLIDVDKKRAEGDALDLIHGTPFTRRANIYAG 60 Query: 202 TPELAAQSDFIVVA--CSLTPATEGLCNKDFFQKMKETAVF 240 SD ++VA P + Q + A Sbjct: 61 DYADLKGSDVVIVAAGVPQKP------GETRLQLLGRNARV 95 >3K8Z-A nrPDB Length = 423 Score = 31.1 bits (69), Expect = 0.73, Method: Composition-based stats. Identities = 15/119 (12%), Positives = 36/119 (30%), Gaps = 22/119 (18%) Query: 148 GYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAA 207 G + + V + G G G +A+ + G + + + E + L Sbjct: 215 GIDIKGARVVVQGFGNAGSYLAKFMHDAGAKVVGISDAY-----GGLYDPEGLDIDYLLD 269 Query: 208 QSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINIS-------------RGDVVNQDD 253 + D L T + N++ + + + + + R +V + Sbjct: 270 RRDSFGTVTKLFNDT--ITNQELLEL--DCDILVPAAIENQITEENAHNIRAKIVVEAA 324 >4YRY-B nrPDB Length = 468 Score = 31.1 bits (69), Expect = 0.74, Method: Composition-based stats. Identities = 11/52 (21%), Positives = 17/52 (32%) Query: 153 QSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPE 204 V +IG G AR G ++ R+ E A + + E Sbjct: 279 GKKVAVIGAGNTAMDAARSALRLGAEKVYIVYRRTEREMPARREEYHHALEE 330 >1VC2-A nrPDB Length = 331 Score = 30.7 bits (68), Expect = 0.83, Method: Composition-based stats. Identities = 12/26 (46%), Positives = 15/26 (57%) Query: 154 STVGIIGLGRIGQAIARRLKPFGVQR 179 VGI G GRIG+ + R L GV+ Sbjct: 1 MKVGINGFGRIGRQVFRILHERGVEV 26 >1Z82-A nrPDB Length = 335 Score = 30.7 bits (68), Expect = 0.84, Method: Composition-based stats. Identities = 18/101 (17%), Positives = 37/101 (36%), Gaps = 18/101 (17%) Query: 158 IIGLGRIGQAIARRLKPFGVQRFLYTGR------------QPRPEEAAEFQAEFVSTPEL 205 ++G G G A+ L G + L+ R P EE+ E+ Sbjct: 19 VLGAGSWGTVFAQMLHENGEEVILWARRKEIVDLINVSHTSPYVEESKITVRATNDLEEI 78 Query: 206 AAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRG 246 + D +V+A + + + + ++ +N+S+G Sbjct: 79 -KKEDILVIAIPV-----QYIREHLLRLPVKPSMVLNLSKG 113 >1PL8-A nrPDB Length = 356 Score = 30.7 bits (68), Expect = 0.87, Method: Composition-based stats. Identities = 13/49 (26%), Positives = 17/49 (34%), Gaps = 1/49 (2%) Query: 153 QSTVGIIGLGRIGQAIARRLKPFG-VQRFLYTGRQPRPEEAAEFQAEFV 200 V + G G IG K G Q + R +A E A+ V Sbjct: 172 GHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLV 220 >2HMT-A nrPDB Length = 144 Score = 30.7 bits (68), Expect = 0.89, Method: Composition-based stats. Identities = 10/45 (22%), Positives = 18/45 (40%) Query: 151 LTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEF 195 + +IGLGR G +I + L G + + + A + Sbjct: 4 IKNKQFAVIGLGRFGGSIVKELHRMGHEVLAVDINEEKVNAYASY 48 >2Z04-A nrPDB Length = 365 Score = 30.7 bits (68), Expect = 0.98, Method: Composition-based stats. Identities = 24/132 (18%), Positives = 44/132 (33%), Gaps = 30/132 (22%) Query: 155 TVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVS-TPELAAQSDFIV 213 TVGI+G G++G + G + + ++ P + E D I Sbjct: 3 TVGILGGGQLGWMTILEGRKLGFKFHVLEDKENAPACRVADRCFRTGQISEFVDSCDII- 61 Query: 214 VACSLTPATEGLCNKDFFQKMK------ETAVFINISRGD----------------VVNQ 251 T E + +K + A+++ SR V+ + Sbjct: 62 -----TYEFEH-IKDEVLEKCESKLIPNPQALYVKKSRIREKLFLKKHGFPVPEFLVIKR 115 Query: 252 DDLYQALASGKI 263 D++ AL S K+ Sbjct: 116 DEIIDALKSFKL 127 >5BUT-A nrPDB Length = 288 Score = 30.7 bits (68), Expect = 0.99, Method: Composition-based stats. Identities = 10/45 (22%), Positives = 18/45 (40%) Query: 151 LTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEF 195 + +IGLGR G +I + L G + + + A + Sbjct: 4 IKNKQFAVIGLGRFGGSIVKELHRMGHEVLAVDINEEKVNAYASY 48 Score = 28.8 bits (63), Expect = 3.4, Method: Composition-based stats. Identities = 10/42 (23%), Positives = 17/42 (40%) Query: 154 STVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEF 195 +IGLGR G +I + L G + + + A + Sbjct: 149 KQFAVIGLGRFGGSIVKELHRMGHEVLAVDINEEKVNAYASY 190 >4R16-A nrPDB Length = 418 Score = 30.7 bits (68), Expect = 0.99, Method: Composition-based stats. Identities = 9/33 (27%), Positives = 12/33 (36%) Query: 154 STVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQ 186 + ++GLG IG A G Y R Sbjct: 1 MRIAVLGLGYIGLPTAIMFASSGYDVVGYDIRS 33 >6JDK-A nrPDB Length = 544 Score = 30.7 bits (68), Expect = 1.0, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 15/45 (33%), Gaps = 6/45 (13%) Query: 129 AIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLK 173 A E G W G T VG++G G G + + Sbjct: 168 AGESFHTGLWPQE------GASFTGKRVGVVGTGASGVQVVQEAS 206 >5J9G-A nrPDB Length = 338 Score = 30.3 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 15/76 (19%), Positives = 26/76 (34%), Gaps = 17/76 (22%) Query: 155 TVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVV 214 +GI G GRIG+ RR+ G E V+ +L + ++ Sbjct: 4 KIGINGFGRIGRLAFRRIMDLG---------------EKSKDIEVVAINDLTTPA--LLA 46 Query: 215 ACSLTPATEGLCNKDF 230 +T G + + Sbjct: 47 HLLKYDSTHGTFDHEV 62 >3ZHB-A nrPDB Length = 309 Score = 30.3 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 23/92 (25%), Positives = 37/92 (40%), Gaps = 2/92 (2%) Query: 156 VGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFV-STPELAAQSDFIVV 214 V +IGLG +GQA+A G ++ + E A+ S E A S +VV Sbjct: 22 VTVIGLGLMGQALAGAFLGAGHPTTVWNRTAAKAEPLVARGAKSAGSVAEAVAASPLVVV 81 Query: 215 ACSLTPATEGLCNKDFFQKMKETAVFINISRG 246 S A L + + + +N++ G Sbjct: 82 CVSDYDAVHALLDPLDGTAL-QGRTLVNLTSG 112 >3VZS-A nrPDB Length = 257 Score = 30.3 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 13/52 (25%), Positives = 22/52 (42%) Query: 160 GLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDF 211 G+G IG AI +RL G + G E Q + + +A++ + Sbjct: 22 GMGGIGTAICQRLAKDGFRVVAGCGPNSPRREKWLEQQKALGFDFIASEGNV 73 >6AON-A nrPDB Length = 478 Score = 30.3 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 25/111 (22%), Positives = 39/111 (35%), Gaps = 7/111 (6%) Query: 98 IRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQSTVG 157 I+V T D D A+ + ++ R LP + KN G +G Sbjct: 137 IKVTGTTD--ADLVAKHVIVATGSSARELPGLPFDEKN----ILSNDGALNIGAVPKKLG 190 Query: 158 IIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQ 208 +IG G IG + + G + + P AA+ Q + A Q Sbjct: 191 VIGAGVIGLEMGSVWRRLGAEVTI-LEAMPEFLAAADQQVAKEALKSFAKQ 240 >5U8W-A nrPDB Length = 481 Score = 30.3 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 10/45 (22%), Positives = 16/45 (35%) Query: 154 STVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAE 198 +G+IG G IG + G + + A E A+ Sbjct: 185 KKLGVIGAGVIGLELGSVWARLGAEVTVLEALDKFLPAADEQIAK 229 >2CZG-A nrPDB Length = 433 Score = 30.3 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 16/101 (15%), Positives = 32/101 (31%), Gaps = 14/101 (13%) Query: 154 STVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPE---EAAEFQAEFVSTPELA---- 206 + ++G G +G+ IA + GV+ P + + L Sbjct: 20 QKILLLGSGELGKEIAIEAQRLGVEVVAVDRYANAPAMQVAHRSYVGNMMDKDFLWSVVE 79 Query: 207 -AQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRG 246 + D I+ P E + F+ K+ + +R Sbjct: 80 REKPDAII------PEIEAINLDALFEFEKDGYFVVPNARA 114 >1L1F-A nrPDB Length = 505 Score = 30.3 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 19/103 (18%), Positives = 31/103 (30%), Gaps = 22/103 (21%) Query: 153 QSTVGIIGLGRIGQAIARRLKPFGVQRFL--------YTGRQPRPEEAAEFQAEFVSTPE 204 T + G G +G R L FG + + P+E +F+ + S Sbjct: 248 DKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILG 307 Query: 205 -----------LAAQSDFIVVACS---LTPATEGLCNKDFFQK 233 L A D ++ A S LT + + Sbjct: 308 FPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAE 350 >4J90-A nrPDB Length = 222 Score = 29.9 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 10/45 (22%), Positives = 18/45 (40%) Query: 151 LTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEF 195 + +IGLGR G +I + L G + + + A + Sbjct: 4 IKNKQFAVIGLGRFGGSICKELHRMGHEVLAVDINEEKVNAYASY 48 >3OJO-A nrPDB Length = 431 Score = 29.9 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 17/87 (19%), Positives = 27/87 (31%), Gaps = 18/87 (20%) Query: 153 QSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQ--AEFVSTPELAAQ-- 208 S + ++GLG IG + GV Q ++ Q E E+ + Sbjct: 11 GSKLTVVGLGYIGLPTSIMFAKHGVDVLGVDINQQTIDKLQNGQISIEEPGLQEVYEEVL 70 Query: 209 -------------SDFIVVACSLTPAT 222 SD ++A TP Sbjct: 71 SSGKLKVSTTPEASDVFIIAVP-TPNN 96 >2DQ4-A nrPDB Length = 343 Score = 29.9 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 16/71 (22%), Positives = 26/71 (36%), Gaps = 3/71 (4%) Query: 146 LCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQP-RPEEAAEFQAEFVST-- 202 G G++ +V I G G IG A ++ G L + P R A + V+ Sbjct: 158 YAGSGVSGKSVLITGAGPIGLMAAMVVRASGAGPILVSDPNPYRLAFARPYADRLVNPLE 217 Query: 203 PELAAQSDFIV 213 +L + Sbjct: 218 EDLLEVVRRVT 228 >3G0O-A nrPDB Length = 303 Score = 29.9 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 34/183 (18%), Positives = 58/183 (31%), Gaps = 33/183 (18%) Query: 152 TQSTVGIIGLGRIGQAIARR-----LKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELA 206 T VGI+GLG +G AR L +G + A S E A Sbjct: 6 TDFHVGIVGLGSMGMGAARSCLRAGLSTWGADL---NPQACANLLAEGACGAAASAREFA 62 Query: 207 AQSDFIVVACSLTPATEG-LCNKDFFQ-KMKETAVFINISRGDVVNQDDLYQALASGKIA 264 D +V+ L +D MK + + S + ++ AL + + Sbjct: 63 GVVDALVILVVNAAQVRQVLFGEDGVAHLMKPGSAVMVSSTISSADAQEIAAALTALNL- 121 Query: 265 AAGLDVTSPEPLPTNHPLLTLKNCVILPHIGSATHRTRNTMSLLAANNLLAGLRGEPMPS 324 N + P G A + M+++A+ + A R +P+ Sbjct: 122 ----------------------NMLDAPVSGGAVKAAQGEMTVMASGSEAAFTRLKPVLD 159 Query: 325 ELK 327 + Sbjct: 160 AVA 162 >3LK7-A nrPDB Length = 451 Score = 29.9 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 17/94 (18%), Positives = 30/94 (31%), Gaps = 7/94 (7%) Query: 149 YGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYT----GRQPRPEEAAEFQAEFV---S 201 V ++GL R G+A AR L G + P + E + V Sbjct: 5 TTFENKKVLVLGLARSGEAAARLLAKLGAIVTVNDGKPFDENPTAQSLLEEGIKVVCGSH 64 Query: 202 TPELAAQSDFIVVACSLTPATEGLCNKDFFQKMK 235 EL + ++ P + K +++ Sbjct: 65 PLELLDEDFCYMIKNPGIPYNNPMVKKALEKQIP 98 >3E5R-O nrPDB Length = 337 Score = 29.9 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 9/18 (50%), Positives = 12/18 (66%) Query: 155 TVGIIGLGRIGQAIARRL 172 +GI G GRIG+ +AR Sbjct: 5 KIGINGFGRIGRLVARVA 22 >3QE3-A nrPDB Length = 355 Score = 29.9 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 28/77 (36%), Gaps = 11/77 (14%) Query: 152 TQSTVG----IIGLGRIGQAIARRLKPFG-VQRFLYTGRQPRPEEAAEFQAEF------V 200 T+G + G G IG K G Q + R +A E A+F Sbjct: 166 AGVTLGNKVLVCGAGPIGLVNLLAAKAMGAAQVVVTDLSASRLSKAKEVGADFILEISNE 225 Query: 201 STPELAAQSDFIVVACS 217 S E+A + + ++ + Sbjct: 226 SPEEIAKKVEGLLGSKP 242 >3NDC-A nrPDB Length = 264 Score = 29.9 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 10/46 (21%), Positives = 17/46 (36%), Gaps = 5/46 (10%) Query: 225 LCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDV 270 L + A +N + ++ D + +A AAG DV Sbjct: 39 LVPEALLAHCPPGAKIVNTA---PMSLDAIIDTIAEAH--AAGQDV 79 >1HYH-A nrPDB Length = 309 Score = 29.9 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 12/24 (50%), Positives = 15/24 (62%) Query: 154 STVGIIGLGRIGQAIARRLKPFGV 177 +GIIGLG +G A+A L GV Sbjct: 2 RKIGIIGLGNVGAAVAHGLIAQGV 25 >3K92-A nrPDB Length = 424 Score = 29.9 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 21/137 (15%), Positives = 39/137 (28%), Gaps = 27/137 (19%) Query: 148 GYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQ-----------PRPEEAAEFQ 196 G L + + I G G G +A+ + G + + P + + Sbjct: 216 GIKLQNARIIIQGFGNAGSFLAKFMHDAGAKVIGISDANGGLYNPDGLDIPYLLDKRDSF 275 Query: 197 AEFVST-------PELAAQ-SDFIVVAC---SLTPATEGLCNKDFFQKMKETAVFINIS- 244 + EL + D +V A +T + I+ + Sbjct: 276 GMVTNLFTDVITNEELLEKDCDILVPAAISNQITAKNAHNIQASIVVERANGPTTIDATK 335 Query: 245 ----RGDVVNQDDLYQA 257 RG ++ D L A Sbjct: 336 ILNERGVLLVPDILASA 352 >6FG0-A nrPDB Length = 352 Score = 29.6 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 25/118 (21%), Positives = 40/118 (33%), Gaps = 20/118 (16%) Query: 93 IKKRGIRVGYTPDV-LTDTTAELAVSLLLTTCRRLPE-------AIEEVKNGGWTSWKPL 144 GI P + AE +++ + R L A + + G T + + Sbjct: 109 AADLGIT---PPGYGSPGSMAEY---MIVDSARHLVPIGDLDPVAAAPLTDAGLTPYHAI 162 Query: 145 ----WLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAE 198 L G G T +G+ GLG +G I R + + R A E A+ Sbjct: 163 SRVLPLLGPGSTAVVIGVGGLGHVGIQILRAVSA--ARVIAVDLDDDRLALAREVGAD 218 >3FBT-A nrPDB Length = 282 Score = 29.6 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 16/88 (18%), Positives = 30/88 (34%), Gaps = 4/88 (4%) Query: 158 IIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAA-QSDFIVVAC 216 ++G G +A+ + LK + R P + + +S EL+ + D I+ Sbjct: 127 VLGSGGAARAVLQYLKDNFAKDIYVVTRNPEKTSEIYGEFKVISYDELSNLKGDVIINCT 186 Query: 217 S---LTPATEGLCNKDFFQKMKETAVFI 241 E +K+ K I Sbjct: 187 PKGMYPKEGESPVDKEVVAKFSSAVDLI 214 >3EZY-A nrPDB Length = 344 Score = 29.6 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 19/75 (25%), Positives = 27/75 (36%), Gaps = 7/75 (9%) Query: 155 TVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAE------FVSTPELAAQ 208 +G+IGLGRIG A LK LY R + E + + + EL Sbjct: 4 RIGVIGLGRIGTIHAENLKMID-DAILYAISDVREDRLREMKEKLGVEKAYKDPHELIED 62 Query: 209 SDFIVVACSLTPATE 223 + V + T Sbjct: 63 PNVDAVLVCSSTNTH 77 >6N7F-A nrPDB Length = 453 Score = 29.6 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 13/53 (24%), Positives = 21/53 (39%), Gaps = 1/53 (1%) Query: 154 STVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELA 206 ++G G I +A L G + L+ R RP + + V E+A Sbjct: 171 KRTAVVGAGYIAVELAGVLHALGSKTDLF-IRHDRPLRSFDKTIVDVLVDEMA 222 >4EJ6-A nrPDB Length = 370 Score = 29.6 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 13/52 (25%), Positives = 19/52 (36%) Query: 152 TQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTP 203 STV I+G G IG + + G + + RQ AE + Sbjct: 182 AGSTVAILGGGVIGLLTVQLARLAGATTVILSTRQATKRRLAEEVGATATVD 233 >3GGO-A nrPDB Length = 314 Score = 29.6 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 27/65 (41%), Gaps = 2/65 (3%) Query: 149 YGLTQSTVGIIGLGRIGQAIARRLKPFGV--QRFLYTGRQPRPEEAAEFQAEFVSTPELA 206 L+ V I+G+G +G + A+ L+ G + + Y +A + T +A Sbjct: 29 KSLSMQNVLIVGVGFMGGSFAKSLRRSGFKGKIYGYDINPESISKAVDLGIIDEGTTSIA 88 Query: 207 AQSDF 211 DF Sbjct: 89 KVEDF 93 >4ILK-A nrPDB Length = 359 Score = 29.6 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 15/51 (29%), Positives = 23/51 (45%), Gaps = 2/51 (3%) Query: 152 TQSTVGIIGLGRIGQAIARRLKP-FGVQ-RFLYTGRQPRPEEAAEFQAEFV 200 TV + G G IG I + LK + V+ + R E+A E A++ Sbjct: 180 ENDTVLVYGAGPIGLTIVQVLKGVYNVKNVIVADRIDERLEKAKESGADWA 230 >5TR3-A nrPDB Length = 481 Score = 29.6 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 7/26 (26%), Positives = 11/26 (42%) Query: 154 STVGIIGLGRIGQAIARRLKPFGVQR 179 +G+IG G IG + G + Sbjct: 185 KRLGVIGAGVIGLELGSVWARLGAEV 210 >4BO1-A nrPDB Length = 269 Score = 29.6 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 26/126 (20%), Positives = 39/126 (30%), Gaps = 17/126 (13%) Query: 135 NGGWTSWKPLWLCGYGLTQSTVGIIGLGR-IGQAIARRLKPFGVQRFLYTGRQPRPEEAA 193 +G + L+ L + G R IGQAIA L G E+ A Sbjct: 9 SGVDLGTENLYFQSMSLQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIA 68 Query: 194 E-----------FQAEFVSTPELAAQSDFIVVAC--SL-TPATEGLCNKDFFQKMKETAV 239 E + S +AA + I L G+ + +MK+ Sbjct: 69 ETLKANGVEGAGLVLDVSSDESVAATLEHIQQHLGQPLIVVNNAGITRDNLLVRMKDDEW 128 Query: 240 F--INI 243 F +N Sbjct: 129 FDVVNT 134 >3IP1-A nrPDB Length = 404 Score = 29.6 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 22/110 (20%), Positives = 31/110 (28%), Gaps = 12/110 (10%) Query: 101 GYTPDVLTDTT---AELAVSLLLTTCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQS--- 154 + A+ A S L + E G + + Sbjct: 155 FNVDGAFAEYVKVDAKYAWS--LRELEGVYEGDRLFLAGSLVEPTSVAYNAVIVRGGGIR 212 Query: 155 ---TVGIIGLGRIGQAIARRLKPFGV-QRFLYTGRQPRPEEAAEFQAEFV 200 V I+G G IG A LK G + L + R A E A+ V Sbjct: 213 PGDNVVILGGGPIGLAAVAILKHAGASKVILSEPSEVRRNLAKELGADHV 262 >4FHN-X nrPDB Length = 450 Score = 29.6 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 11/60 (18%), Positives = 15/60 (25%), Gaps = 2/60 (3%) Query: 148 GYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAA 207 G G V + G G + Q + FG + T E L Sbjct: 230 GMGFEGMRVSVSGSGNVAQYAIEKAMEFGARVI--TASDSSGTVVDESGFTKEKLARLIE 287 >6DKH-A nrPDB Length = 346 Score = 29.6 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 12/40 (30%), Positives = 15/40 (37%) Query: 150 GLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRP 189 L V I G+G IG I +K G + PR Sbjct: 170 ELQGKRVFISGVGPIGCLIVSAVKTLGAAEIVCADVSPRS 209 >5Y77-A nrPDB Length = 473 Score = 29.6 bits (65), Expect = 2.3, Method: Composition-based stats. Identities = 18/52 (34%), Positives = 24/52 (46%), Gaps = 1/52 (1%) Query: 154 STVGIIGLGRIGQAIARRLKPFGVQRFLYTGR-QPRPEEAAEFQAEFVSTPE 204 V IIG G G +AR L G Q L+ R PR E A ++ ++ E Sbjct: 9 RQVTIIGAGLAGTLVARLLARNGWQVNLFERRPDPRIETGARGRSINLALAE 60 >4Z0H-O nrPDB Length = 334 Score = 29.6 bits (65), Expect = 2.3, Method: Composition-based stats. Identities = 9/16 (56%), Positives = 12/16 (75%) Query: 155 TVGIIGLGRIGQAIAR 170 +GI G GRIG+ +AR Sbjct: 3 RIGINGFGRIGRLVAR 18 >2G5C-A nrPDB Length = 281 Score = 29.2 bits (64), Expect = 2.3, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 25/58 (43%), Gaps = 2/58 (3%) Query: 156 VGIIGLGRIGQAIARRLKPFGV--QRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDF 211 V I+G+G +G + A+ L+ G + + Y +A + T +A DF Sbjct: 4 VLIVGVGFMGGSFAKSLRRSGFKGKIYGYDINPESISKAVDLGIIDEGTTSIAKVEDF 61 >6HRD-A nrPDB Length = 317 Score = 29.2 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 9/40 (22%), Positives = 17/40 (42%) Query: 154 STVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAA 193 VG++G G++G IA GV+ ++ + Sbjct: 26 QRVGVVGAGQMGSGIAEVSARAGVEVTVFEPAEALITAGR 65 >1LLU-A nrPDB Length = 342 Score = 29.2 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 9/48 (18%), Positives = 16/48 (33%) Query: 153 QSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFV 200 V I G+G +G + + G+ + E A + A Sbjct: 171 GQWVAISGIGGLGHVAVQYARAMGLHVAAIDIDDAKLELARKLGASLT 218 >6DHM-A nrPDB Length = 582 Score = 29.2 bits (64), Expect = 2.5, Method: Composition-based stats. Identities = 10/49 (20%), Positives = 16/49 (32%), Gaps = 5/49 (10%) Query: 153 QSTVGIIGLGRIGQAIARRLKPFGVQRFL-----YTGRQPRPEEAAEFQ 196 T + G G +G R L FG + + P + E + Sbjct: 325 DKTFAVQGFGNVGLHSMRYLHRFGAKCVAVGESDGSIWNPDGIDPKELE 373 >1VSU-A nrPDB Length = 359 Score = 29.2 bits (64), Expect = 2.6, Method: Composition-based stats. Identities = 9/16 (56%), Positives = 12/16 (75%) Query: 155 TVGIIGLGRIGQAIAR 170 T+GI G GRIG+ + R Sbjct: 24 TLGINGFGRIGRLVLR 39 >4OQZ-A nrPDB Length = 289 Score = 29.2 bits (64), Expect = 2.7, Method: Composition-based stats. Identities = 25/98 (25%), Positives = 42/98 (42%), Gaps = 15/98 (15%) Query: 154 STVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIV 213 +V +IGLG +GQA+A G + L+ R + A+ +TPE A ++ +V Sbjct: 3 QSVTVIGLGPMGQAMAAAYLDRGYEVTLWNRTASRADALVARGAKLAATPEQALSANELV 62 Query: 214 VACSLTPATEGLCNKDFFQKMKETA-------VFINIS 244 + L + D + E A V +N+S Sbjct: 63 IL--------SLIDYDAMYGVLEGAEEAVAGRVLVNLS 92 >2YFH-A nrPDB Length = 448 Score = 28.8 bits (63), Expect = 3.1, Method: Composition-based stats. Identities = 11/60 (18%), Positives = 15/60 (25%), Gaps = 2/60 (3%) Query: 148 GYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAA 207 G G V + G G + Q + FG + T E L Sbjct: 226 GMGFEGMRVSVSGSGNVAQYAIEKAMEFGARVI--TASDSSGTVVDESGFTKEKLARLIE 283 >5FI5-A nrPDB Length = 357 Score = 28.8 bits (63), Expect = 3.2, Method: Composition-based stats. Identities = 21/153 (13%), Positives = 39/153 (25%), Gaps = 33/153 (21%) Query: 168 IARRLKPFGVQRFLYTGRQPRPEEAAEFQAEF-----VSTPELAAQSDFIVVACSLTPAT 222 R K FG + + + + EA E + E+ + + P Sbjct: 196 ALRFAKAFGAKVTVISSSLKKKREAFEKFGADSFLVSSNPEEMQGAAGTLDGIIDTIPGN 255 Query: 223 EGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLPTNHPL 282 L + +K I I A P P Sbjct: 256 HSL--EPLLALLKPLGKLI---------------------ILGA-----PEMPFEVPAPS 287 Query: 283 LTLKNCVILPHIGSATHRTRNTMSLLAANNLLA 315 L + V+ + + + A +N++A Sbjct: 288 LLMGGKVMAASTAGSMKEIQEMIEFAAEHNIVA 320 >1GEU-A nrPDB Length = 450 Score = 28.8 bits (63), Expect = 3.3, Method: Composition-based stats. Identities = 7/29 (24%), Positives = 13/29 (44%) Query: 154 STVGIIGLGRIGQAIARRLKPFGVQRFLY 182 V ++G G IG + + G + L+ Sbjct: 168 ERVAVVGAGYIGVELGGVINGLGAKTHLF 196 >3ADO-A nrPDB Length = 319 Score = 28.8 bits (63), Expect = 3.4, Method: Composition-based stats. Identities = 11/40 (27%), Positives = 17/40 (42%) Query: 156 VGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEF 195 V I+G G +G++ A G + LY + A E Sbjct: 9 VLIVGSGLVGRSWAMLFASGGFRVKLYDIEPRQITGALEN 48 >5XW0-A nrPDB Length = 460 Score = 28.8 bits (63), Expect = 3.4, Method: Composition-based stats. Identities = 17/79 (21%), Positives = 24/79 (30%), Gaps = 8/79 (10%) Query: 152 TQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDF 211 V I G G + Q A ++ G + Q E EL AQ+ Sbjct: 220 KGKRVAISGSGNVAQYAALKVIELGGSVVSLSDSQGSLIINGEGSFTPEEI-ELIAQTKV 278 Query: 212 -------IVVACSLTPATE 223 IV A + A + Sbjct: 279 ERKQLASIVGAAPFSDANK 297 >3RWB-A nrPDB Length = 247 Score = 28.8 bits (63), Expect = 3.4, Method: Composition-based stats. Identities = 11/32 (34%), Positives = 15/32 (46%), Gaps = 1/32 (3%) Query: 151 LTQSTVGIIGLGR-IGQAIARRLKPFGVQRFL 181 L T + G + IG+AIA RL G + Sbjct: 4 LAGKTALVTGAAQGIGKAIAARLAADGATVIV 35 >5N2I-A nrPDB Length = 232 Score = 28.8 bits (63), Expect = 3.5, Method: Composition-based stats. Identities = 15/74 (20%), Positives = 30/74 (40%), Gaps = 6/74 (8%) Query: 150 GLTQSTVGIIG-LGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPEL--- 205 ++ ++ ++G G G+ +ARR G + L + R + A E + + Sbjct: 16 DVSGLSIAVLGGTGDQGRGLARRFAMAGHEVILGSRSAERAQAVAAELGEGLPVRGMDNA 75 Query: 206 --AAQSDFIVVACS 217 A D ++VA Sbjct: 76 GAAEAGDVVIVAVP 89 >4UEJ-A nrPDB Length = 346 Score = 28.8 bits (63), Expect = 3.5, Method: Composition-based stats. Identities = 12/52 (23%), Positives = 15/52 (28%), Gaps = 1/52 (1%) Query: 147 CGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQ-RFLYTGRQPRPEEAAEFQA 197 G V IIG G IG + G + + A F A Sbjct: 155 LAQGCENKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGA 206 >3WYB-A nrPDB Length = 334 Score = 28.8 bits (63), Expect = 3.7, Method: Composition-based stats. Identities = 11/63 (17%), Positives = 25/63 (39%), Gaps = 1/63 (1%) Query: 155 TVGIIGLGRIGQAI-ARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIV 213 +GI+G G +G+ + A + ++ R+ A + + + + + D I Sbjct: 5 RIGIVGYGNLGRGVEAAIQQNPDMELVAVFTRRDPKTVAVKSNVKVLHVDDAQSYKDEID 64 Query: 214 VAC 216 V Sbjct: 65 VMI 67 >2VCY-A nrPDB Length = 344 Score = 28.8 bits (63), Expect = 3.7, Method: Composition-based stats. Identities = 10/49 (20%), Positives = 19/49 (38%), Gaps = 4/49 (8%) Query: 164 IGQAIARRLKPFGVQRFLYTGRQPRPEE----AAEFQAEFVSTPELAAQ 208 +GQA+ + G++ +P ++ AE V T E + Sbjct: 167 VGQAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGAEHVITEEELRR 215 >5U1O-A nrPDB Length = 458 Score = 28.8 bits (63), Expect = 3.8, Method: Composition-based stats. Identities = 9/33 (27%), Positives = 15/33 (45%) Query: 154 STVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQ 186 V ++G G I IA L G + L+ ++ Sbjct: 175 KRVAVVGAGYIAVEIAGVLHALGTETHLFVRKE 207 >1WDE-A nrPDB Length = 294 Score = 28.4 bits (62), Expect = 4.0, Method: Composition-based stats. Identities = 24/114 (21%), Positives = 37/114 (32%), Gaps = 9/114 (7%) Query: 18 EGRVALARAADCEVEQWD-SDEPIPAKELERGVAGAHGLLCLLSD--HVDKRILDAAGAN 74 E A+ RA VE + K + A + D + I+ A Sbjct: 25 EALDAVRRADVVYVESYTMPGSSWLYKSVVEAAGEARVVEASRRDLEERSREIVSRALDA 84 Query: 75 LKVISTMS---VGIDHLALDE-IKKRGIRVGYTPDVLTDTTAELAVSLLLTTCR 124 + + T V H +L + G+ V Y P V A A +L+ R Sbjct: 85 VVAVVTAGDPMVATTHSSLAAEALEAGVAVRYIPGVSGVQAARGA--TMLSFYR 136 >3IC9-A nrPDB Length = 492 Score = 28.4 bits (62), Expect = 4.1, Method: Composition-based stats. Identities = 12/65 (18%), Positives = 21/65 (32%), Gaps = 5/65 (7%) Query: 154 STVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVST---PELA--AQ 208 +V + G G IG + + L GV ++ E + E A+ Sbjct: 175 KSVAVFGPGVIGLELGQALSRLGVIVKVFGRSGSVANLQDEEMKRYAEKTFNEEFYFDAK 234 Query: 209 SDFIV 213 + I Sbjct: 235 ARVIS 239 >5ZZ6-A nrPDB Length = 208 Score = 28.4 bits (62), Expect = 4.2, Method: Composition-based stats. Identities = 19/119 (15%), Positives = 35/119 (29%), Gaps = 23/119 (19%) Query: 122 TCRRLPEAIEEVKN-----GGWTSWKPLWLCG--YGLTQSTVGI--------IGLGRIGQ 166 RRL +++ G + + Y +G+ +G G IG+ Sbjct: 36 LARRLDLKASQIRKDLSYFGEFGKRGVGYNVEHLYDAIGEILGVKKEWKLVVVGAGNIGR 95 Query: 167 AIA--RRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVS----TPELAAQ--SDFIVVACS 217 A+A +K G + P VS + + + V+A Sbjct: 96 AVANYTVMKEKGFRIIGIFDSDPSKIGKEAAPGLTVSDVSELEKFVEEHGVEIGVIAVP 154 >2NVK-X nrPDB Length = 488 Score = 28.4 bits (62), Expect = 4.2, Method: Composition-based stats. Identities = 9/26 (34%), Positives = 13/26 (50%), Gaps = 1/26 (3%) Query: 153 QSTVGIIGLGRIGQAIARRLKPFGVQ 178 T+ ++G G IG A LK G + Sbjct: 188 GKTL-VVGAGYIGLECAGFLKGLGYE 212 >3LAD-A nrPDB Length = 476 Score = 28.4 bits (62), Expect = 4.8, Method: Composition-based stats. Identities = 21/114 (18%), Positives = 36/114 (31%), Gaps = 11/114 (9%) Query: 155 TVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVV 214 +G+IG G IG + G + + E A+ L Q I++ Sbjct: 182 KLGVIGAGVIGLELGSVWARLGAEVTVLEAMDKFLPAVDEQVAKEAQKI-LTKQGLKILL 240 Query: 215 ACSLTPA-------TEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASG 261 +T T + + + + + + R V DL A SG Sbjct: 241 GARVTGTEVKNKQVTVKFVDAEGEKSQAFDKLIVAVGRRPV--TTDLLAA-DSG 291 >4AP1-A nrPDB Length = 549 Score = 28.0 bits (61), Expect = 5.1, Method: Composition-based stats. Identities = 28/144 (19%), Positives = 38/144 (26%), Gaps = 28/144 (19%) Query: 27 ADCEVEQWDSDEPIPAKELE---RGVAGAHGLL--CLLSDHVDKRILDAAGANLKVISTM 81 + E E S++ E+ VA L V +LD L+ Sbjct: 83 PELEQEWNWSEKYATQPEILAYLEHVADRFDLRRDIRFDTRVTSAVLDE--EGLRWTVRT 140 Query: 82 SVGIDHLALDEIKKRGIRVGYTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNGGWTSW 141 G DE+ R + V P +T A G Sbjct: 141 DRG------DEVSARFLVVAAGPLSNANTPA-------------FDGLDRF--TGDIVHT 179 Query: 142 KPLWLCGYGLTQSTVGIIGLGRIG 165 G T VG+IG G G Sbjct: 180 ARWPHDGVDFTGKRVGVIGTGSSG 203 >4AYX-A nrPDB Length = 595 Score = 28.0 bits (61), Expect = 5.3, Method: Composition-based stats. Identities = 14/70 (20%), Positives = 22/70 (31%), Gaps = 10/70 (14%) Query: 218 LTPATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPEPLP 277 L E L + + M V + R + ++ L GKI G Sbjct: 514 LDAENEYLVQEALDRLMDGRTVLVIAHRLSTIKNANMVAVLDQGKITEYG---------- 563 Query: 278 TNHPLLTLKN 287 + LL+ N Sbjct: 564 KHEELLSKPN 573 >3S2F-A nrPDB Length = 340 Score = 28.0 bits (61), Expect = 5.4, Method: Composition-based stats. Identities = 9/48 (18%), Positives = 16/48 (33%) Query: 153 QSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFV 200 V I G+G +G + + G++ + A AE Sbjct: 167 GQWVVISGIGGLGHVAVQYARAMGLRVAAVDIDDAKLNLARRLGAEVA 214 >2WNI-A nrPDB Length = 418 Score = 28.0 bits (61), Expect = 5.4, Method: Composition-based stats. Identities = 9/37 (24%), Positives = 13/37 (35%) Query: 207 AQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINI 243 AQ+ I L L N + K +V +N Sbjct: 233 AQASQITALLPLLTENYDLSNDVLYTAQKRGSVLLNA 269 >1N5W-C nrPDB Length = 288 Score = 28.0 bits (61), Expect = 5.4, Method: Composition-based stats. Identities = 14/70 (20%), Positives = 23/70 (32%), Gaps = 3/70 (4%) Query: 190 EEAAEFQAEFVSTPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAVFINISRG-DV 248 EE + ++T SDF+ + T L + M + N + G Sbjct: 65 EEGTDVVIGAMTTQHALIGSDFLAAKLPIIRETSLLIADPQIRYM--GTIGGNAANGDPG 122 Query: 249 VNQDDLYQAL 258 + L Q L Sbjct: 123 NDMPALMQCL 132 >3MJ4-A nrPDB Length = 397 Score = 28.0 bits (61), Expect = 5.5, Method: Composition-based stats. Identities = 9/28 (32%), Positives = 13/28 (46%) Query: 158 IIGLGRIGQAIARRLKPFGVQRFLYTGR 185 I+G G G +A RL G + + R Sbjct: 34 IVGAGFAGSVLAERLASSGQRVLIVDRR 61 >4B1B-A nrPDB Length = 542 Score = 28.0 bits (61), Expect = 5.7, Method: Composition-based stats. Identities = 9/41 (21%), Positives = 15/41 (36%) Query: 158 IIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAE 198 +IG G G A A+ G + L+ +P + Sbjct: 47 VIGGGPGGMASAKEAAAHGARVLLFDYVKPSSQGTKWGIGG 87 >6BPF-A nrPDB Length = 265 Score = 28.0 bits (61), Expect = 5.8, Method: Composition-based stats. Identities = 21/114 (18%), Positives = 34/114 (29%), Gaps = 18/114 (15%) Query: 60 SDHVDKRILDAA--GANLKVISTMSVGIDHLALDE-------IKKRGIRVGYTPDVLTDT 110 SD+ ++ A G S+G D LD +R TP + + Sbjct: 107 SDNAAMNLILAKLGGPQKVTAFARSIGDDKFRLDRNEPSLNTAIPGDLRDTSTPRAMALS 166 Query: 111 TAELAVSLLLT---------TCRRLPEAIEEVKNGGWTSWKPLWLCGYGLTQST 155 +LA+ L R ++ G + W G G +T Sbjct: 167 LQKLALGDALGQVQREKLSHWLRGNTTGAASIRAGLPSGWSVGDKTGSGDYGTT 220 >5T5Q-A nrPDB Length = 247 Score = 28.0 bits (61), Expect = 6.0, Method: Composition-based stats. Identities = 14/67 (20%), Positives = 22/67 (32%), Gaps = 11/67 (16%) Query: 149 YGLTQSTVGIIGL-GRIGQAIARRLKPFGVQRF----------LYTGRQPRPEEAAEFQA 197 + T+ + G G IG+AIA G + PE A +A Sbjct: 5 FEFENRTLVLTGANGGIGRAIAELFHASGANLVLTDLDREGLDAFAASLGSPERIATIKA 64 Query: 198 EFVSTPE 204 + S + Sbjct: 65 DASSADD 71 >1XCB-A nrPDB Length = 211 Score = 28.0 bits (61), Expect = 6.0, Method: Composition-based stats. Identities = 12/55 (21%), Positives = 23/55 (41%), Gaps = 4/55 (7%) Query: 156 VGIIGLGRIGQAIARRLKPFG--VQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQ 208 + I+G+GR+G A+A FG + + P + + + +L Q Sbjct: 83 LCIVGMGRLGSALADY-PGFGESFELRGFFDVDP-EKVGRPVRGGVIEHVDLLPQ 135 >4E4T-A nrPDB Length = 419 Score = 28.0 bits (61), Expect = 6.2, Method: Composition-based stats. Identities = 11/69 (15%), Positives = 25/69 (36%), Gaps = 6/69 (8%) Query: 151 LTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEF------QAEFVSTPE 204 L + +G++G G++G+ + G + + P A + + E Sbjct: 33 LPGAWLGMVGGGQLGRMFCFAAQSMGYRVAVLDPDPASPAGAVADRHLRAAYDDEAALAE 92 Query: 205 LAAQSDFIV 213 LA + + Sbjct: 93 LAGLCEAVS 101 >3GRP-A nrPDB Length = 266 Score = 28.0 bits (61), Expect = 6.2, Method: Composition-based stats. Identities = 17/66 (25%), Positives = 26/66 (39%), Gaps = 1/66 (1%) Query: 136 GGWTSWKPLWLCGYGLTQSTVGIIG-LGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAE 194 G + + LT + G G IG+AIAR G L+ R+ + +E A Sbjct: 10 GTLEAQTQGPGSMFKLTGRKALVTGATGGIGEAIARCFHAQGAIVGLHGTREDKLKEIAA 69 Query: 195 FQAEFV 200 + V Sbjct: 70 DLGKDV 75 >3WTC-A nrPDB Length = 262 Score = 27.6 bits (60), Expect = 6.9, Method: Composition-based stats. Identities = 19/96 (19%), Positives = 31/96 (32%), Gaps = 9/96 (9%) Query: 150 GLTQSTVGIIGLGR-IGQAIARRLKPFGVQRFLYTGRQP----RPEEAAEFQAEFVSTPE 204 L+ + G + IG+AIA RL G L +Q +E V+ Sbjct: 5 SLSGKIAAVTGAAQGIGKAIALRLAKDGADVILLDVKQDTLAETAKEVEALGRRAVALTA 64 Query: 205 LAAQSDFIVVACSLTPATEG----LCNKDFFQKMKE 236 + D + T G + N ++K Sbjct: 65 DISNRDQFRSTLADAAKTLGGLDIMVNNAGICQVKP 100 >4DYD-A nrPDB Length = 283 Score = 27.6 bits (60), Expect = 7.2, Method: Composition-based stats. Identities = 13/57 (22%), Positives = 21/57 (36%), Gaps = 2/57 (3%) Query: 156 VGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAE--FQAEFVSTPELAAQSD 210 V ++G G +G IA + G Y + A + V E+A +D Sbjct: 7 VTVLGTGVLGSQIAFQTAFHGFAVTAYDINTDALDAAKKRFEGLAAVYEKEVAGAAD 63 >1PJB-A nrPDB Length = 361 Score = 27.6 bits (60), Expect = 7.4, Method: Composition-based stats. Identities = 15/103 (14%), Positives = 34/103 (33%), Gaps = 15/103 (14%) Query: 166 QAIARRLKPFGVQRFLYTGR-QPRPEEAAEFQAEFV-------STPELAAQSDFIVVACS 217 A+ G Q ++ + F + A++D ++ A Sbjct: 180 TEAAKMAVGLGAQVQIFDINVERLSYLETLFGSRVELLYSNSAEIETAVAEADLLIGAV- 238 Query: 218 LTPATEG--LCNKDFFQKMKETAVFINISRGDVVNQDDLYQAL 258 L P L ++M+ +V ++++ V+Q + L Sbjct: 239 LVPGRRAPILVPASLVEQMRTGSVIVDVA----VDQGGCVETL 277 >5KSD-A nrPDB Length = 833 Score = 27.6 bits (60), Expect = 7.6, Method: Composition-based stats. Identities = 13/85 (15%), Positives = 30/85 (35%), Gaps = 6/85 (7%) Query: 35 DSDEPIPAKELERGVAGAHGLLCLLSDHVDKRILDAAGANLKVISTMSVGIDHLALDEIK 94 D + + +E + A G + +H I+ ++ G++ +K Sbjct: 530 HKDANLASIPVEELIEKADGFAGVFPEH-KYEIVKKLQERKHIVGMTGDGVN--DAPALK 586 Query: 95 KR--GIRVGYTPDVLTDTTAELAVS 117 K GI V D +++ ++ Sbjct: 587 KADIGIAVADATDA-ARGASDIVLT 610 >6MGG-A nrPDB Length = 296 Score = 27.6 bits (60), Expect = 7.7, Method: Composition-based stats. Identities = 18/121 (14%), Positives = 47/121 (38%), Gaps = 12/121 (9%) Query: 49 VAGAHGLLCLLSDH-VDKRILDAAGANLKVISTMSVGIDHLAL----DEIKKRGIRVG-- 101 GA + + V ++ + +K++ ++ G+ L + + +K + +RV Sbjct: 63 ATGADASVIYVPAPFVKDSAIEVIDSGVKLVVIITEGVPTLDMLVVKEYLKDKDVRVIGP 122 Query: 102 YTPDVLTDTTAELAVSLLLTTCRRLPEAIEEVKNG--GWTSWKPLWLCGYGLTQSTVGII 159 P ++T E + ++ + ++G + + G+G + +GI Sbjct: 123 NCPGIITPG--ECKIGIMPGHIHMKGKVGIISRSGTLTYEAVAQTTKLGFG-QSTCIGIG 179 Query: 160 G 160 G Sbjct: 180 G 180 >3X43-A nrPDB Length = 332 Score = 27.6 bits (60), Expect = 8.2, Method: Composition-based stats. Identities = 8/49 (16%), Positives = 16/49 (32%) Query: 226 CNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTSPE 274 + + +K + + G+V + A + A D S E Sbjct: 52 LDAEAKGLLKPGDTIVECTSGNVGIALAMVAAARGYRFVAVMGDTYSVE 100 >3L60-A nrPDB Length = 250 Score = 27.6 bits (60), Expect = 8.5, Method: Composition-based stats. Identities = 22/84 (26%), Positives = 31/84 (36%), Gaps = 6/84 (7%) Query: 87 HLALDEIKKRGIRVGYTPDVLTDTTAELA--VSLLLTTCRRLPEAIEEVKNGGWTSWKPL 144 HL +RG+ V D T ELA V+ L+T R E++ +T Sbjct: 105 HLGFGAATERGLLVPVVTDAQDKNTRELASRVAELITGAREGTLTPAELRGSTFTVSNFG 164 Query: 145 WLCGYG----LTQSTVGIIGLGRI 164 L + I+GLG I Sbjct: 165 ALGVDDGVPVINHPEAAILGLGAI 188 >2DC1-A nrPDB Length = 236 Score = 27.2 bits (59), Expect = 9.1, Method: Composition-based stats. Identities = 13/48 (27%), Positives = 21/48 (43%) Query: 156 VGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTP 203 VG+IG G IG+ +A L+ G + + E+ EF+ Sbjct: 3 VGLIGYGAIGKFLAEWLERNGFEIAAILDVRGEHEKMVRGIDEFLQRE 50 >2ZCU-A nrPDB Length = 286 Score = 27.2 bits (59), Expect = 9.2, Method: Composition-based stats. Identities = 20/130 (15%), Positives = 35/130 (26%), Gaps = 15/130 (11%) Query: 98 IRVGYTPDVLTDTTAELAV-----SLLLTTCRRLPEAIEEVKNGGWTS---WKPLWLCGY 149 I + L E + S ++ R +A G + Sbjct: 2 IAITGATGQLGHYVIESLMKTVPASQIVAIVRNPAKAQALAAQGITVRQADYGDEAALTS 61 Query: 150 GLTQ-STVGIIGLGRIGQA------IARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVST 202 L + +I +GQ + K GV+ YT E + T Sbjct: 62 ALQGVEKLLLISSSEVGQRAPQHRNVINAAKAAGVKFIAYTSLLHADTSPLGLADEHIET 121 Query: 203 PELAAQSDFI 212 ++ A S + Sbjct: 122 EKMLADSGIV 131 >2UVD-A nrPDB Length = 246 Score = 27.2 bits (59), Expect = 9.3, Method: Composition-based stats. Identities = 24/118 (20%), Positives = 36/118 (30%), Gaps = 32/118 (27%) Query: 151 LTQSTVGIIGLGR-IGQAIARRLKPFGVQRFL-YTGRQPRPEEAAEFQAEFVS------- 201 L + G R IG+AIA L G + Y G + + E + + S Sbjct: 2 LKGKVALVTGASRGIGRAIAIDLAKQGANVVVNYAGNEQKANEVVDEIKKLGSDAIAVRA 61 Query: 202 --------------TPELAAQSDFIVVACSLTPATEGLCNKDFFQKMKETAV--FINI 243 T ++ Q D +V +T +MKE IN Sbjct: 62 DVANAEDVTNMVKQTVDVFGQVDILVNNAGVTKDN-------LLMRMKEEEWDTVINT 112 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.143 0.382 Lambda K H 0.267 0.0440 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,701,844 Number of Sequences: 36641 Number of extensions: 540743 Number of successful extensions: 2717 Number of sequences better than 10.0: 317 Number of HSP's better than 10.0 without gapping: 290 Number of HSP's successfully gapped in prelim test: 120 Number of HSP's that attempted gapping in prelim test: 2040 Number of HSP's gapped (non-prelim): 443 length of query: 328 length of database: 10,336,785 effective HSP length: 97 effective length of query: 231 effective length of database: 6,782,608 effective search space: 1566782448 effective search space used: 1566782448 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 59 (27.2 bits)