BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9UBE0 (346 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6CWZ-C nrPDB 711 0.0 4P22-A nrPDB 120 6e-28 1TT5-A nrPDB 102 2e-22 1JWB-B nrPDB 62 3e-10 3KYD-B nrPDB 58 7e-09 3KYC-B nrPDB 57 8e-09 1YOV-B nrPDB 57 9e-09 2NVU-B nrPDB 57 1e-08 1ZFN-A nrPDB 53 2e-07 4RDI-A nrPDB 45 5e-05 3VH2-A nrPDB 42 3e-04 3T7E-A nrPDB 42 5e-04 2NMV-A nrPDB 34 0.10 3H86-B nrPDB 34 0.10 4H59-A nrPDB 29 3.1 3FPN-B nrPDB 28 5.3 1D9Z-A nrPDB 28 5.9 4XGI-A nrPDB 27 9.2 2FOR-A nrPDB 27 10.0 >6CWZ-C nrPDB Length = 346 Score = 711 bits (1836), Expect = 0.0, Method: Compositional matrix adjust. Identities = 346/346 (100%), Positives = 346/346 (100%) Query: 1 MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV 60 MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV Sbjct: 1 MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV 60 Query: 61 KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE 120 KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE Sbjct: 61 KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE 120 Query: 121 SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK 180 SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK Sbjct: 121 SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK 180 Query: 181 VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY 240 VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY Sbjct: 181 VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY 240 Query: 241 FLLQVLLKFRTDKGRDPSSDTYEEDSELLLQIRNDVLDSLGISPDLLPEDFVRYCFSEMA 300 FLLQVLLKFRTDKGRDPSSDTYEEDSELLLQIRNDVLDSLGISPDLLPEDFVRYCFSEMA Sbjct: 241 FLLQVLLKFRTDKGRDPSSDTYEEDSELLLQIRNDVLDSLGISPDLLPEDFVRYCFSEMA 300 Query: 301 PVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGMKGNGIVECLGPK 346 PVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGMKGNGIVECLGPK Sbjct: 301 PVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGMKGNGIVECLGPK 346 >4P22-A nrPDB Length = 446 Score = 120 bits (302), Expect = 6e-28, Method: Compositional matrix adjust. Identities = 109/388 (28%), Positives = 157/388 (40%), Gaps = 73/388 (18%) Query: 19 YDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGA 78 Y RQ+ + G EA KRL+ S VL+ GL+GLG EIAKN+IL GVK +T+ D D + Sbjct: 62 YSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTAQWADLSS 121 Query: 79 QFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDV 138 QF +R +G+NRAE S R LN V V T + E F + F V LT + Sbjct: 122 QFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPLV---EDFLSGFQVVVLTNTPLED 178 Query: 139 IVKVDQICHKNSIKFFTGDVFGYHGYTFANL----------GEHEFVEEKTKVAKVSQGV 188 ++V + CH IK D G G F + GE + V K + GV Sbjct: 179 QLRVGEFCHNRGIKLVVADTRGLFGQLFCDFGEEMILTDSNGEQPLSAMVSMVTKDNPGV 238 Query: 189 EDGPDTKRAKLDSSE--------------------------------------------- 203 D R +S + Sbjct: 239 VTCLDEARHGFESGDFVSFSEVQGMVELNGNQPMEIKVLGPYTFSICDTSNFSDYIRGGI 298 Query: 204 --TTMVKKKVVFCPVKEAL-EVDWSSEKAKAALKRTTSDYFLLQVLLKFRTDKGRDPSSD 260 V KK+ F + +L E D+ A R + Q L +F GR P Sbjct: 299 VSQVKVPKKISFKSLVASLAEPDFVVTDF-AKFSRPAQLHIGFQALHQFCAQHGRPPRPR 357 Query: 261 TYEEDSELLLQIRNDVLDSL-GISPDLLPEDFVR----YCFSEMAPVCAVVGGILAQEIV 315 E+ +EL+ + +L + + L ED +R ++AP+ A +GG+ AQE++ Sbjct: 358 NDEDAAELVALAQAVNARALPAVQQNNLDEDLIRKLAYVAAGDLAPINAFIGGLAAQEVM 417 Query: 316 KALSQRDPPHNNFFFFDGMKGNGIVECL 343 KA S + P + +FD + ECL Sbjct: 418 KACSGKFMPIMQWLYFDAL------ECL 439 >1TT5-A nrPDB Length = 531 Score = 102 bits (255), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 55/162 (33%), Positives = 84/162 (51%), Gaps = 3/162 (1%) Query: 18 QYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPG 77 +YDRQ+RLWG Q+ L ++ V L+ G EI KNL+L G+ T++D QV+ ED G Sbjct: 14 KYDRQLRLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDAG 73 Query: 78 AQFLIRTGSVGRNRAEASLERAQNLNPMVD---VKVDTEDIEKKPESFFTQFDAVCLTCC 134 F ++ S+G+NRAEA++E Q LN V V+ E++ SFF +F V T Sbjct: 74 NNFFLQRSSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVATQL 133 Query: 135 SRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVE 176 +++ + + I +G GY + EH +E Sbjct: 134 PESTSLRLADVLWNSQIPLLICRTYGLVGYMRIIIKEHPVIE 175 Score = 47.4 bits (111), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 30/100 (30%), Positives = 48/100 (48%), Gaps = 5/100 (5%) Query: 240 YFLLQVLLKFRTDKGRDPSSDTY--EEDSELLLQIRNDVLDSLGIS---PDLLPEDFVRY 294 Y +L+ + +F +GR P Y EED L L G+S D +F RY Sbjct: 423 YLMLRAVDRFHKQQGRYPGVSNYQVEEDIGKLKSCLTGFLQEYGLSVMVKDDYVHEFCRY 482 Query: 295 CFSEMAPVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGM 334 +E + A +GG AQE++K ++++ NN + + GM Sbjct: 483 GAAEPHTIAAFLGGAAAQEVIKIITKQFVIFNNTYIYSGM 522 >1JWB-B nrPDB Length = 249 Score = 62.0 bits (149), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 36/100 (36%), Positives = 60/100 (60%), Gaps = 2/100 (2%) Query: 11 ISEEEAAQYDRQIRLWGLE--AQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDH 68 +S++E +Y+RQI L G + Q+ L+ SRVL+VGL GLG ++ L AGV LT+LD Sbjct: 4 LSDQEMLRYNRQIILRGFDFDGQEALKDSRVLIVGLGGLGCAASQYLASAGVGNLTLLDF 63 Query: 69 EQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDV 108 + V+ + Q L +VG+ + E++ + +NP + + Sbjct: 64 DTVSLSNLQRQTLHSDATVGQPKVESARDALTRINPHIAI 103 >3KYD-B nrPDB Length = 551 Score = 57.8 bits (138), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 37/129 (28%), Positives = 60/129 (46%), Gaps = 4/129 (3%) Query: 38 RVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLE 97 RVL+VG G+G E+ KNL+L G + ++D + + + QFL + VGR++A+ + E Sbjct: 21 RVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKE 80 Query: 98 RAQNLNPMVDVKVDTEDIEKKPE---SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFF 154 P ++ V D P+ FF QF V +R V+++C + Sbjct: 81 SVLQFYPKANI-VAYHDSIMNPDYNVEFFRQFILVMNALDNRAARNHVNRMCLAADVPLI 139 Query: 155 TGDVFGYHG 163 GY G Sbjct: 140 ESGTAGYLG 148 >3KYC-B nrPDB Length = 660 Score = 57.4 bits (137), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 37/129 (28%), Positives = 60/129 (46%), Gaps = 4/129 (3%) Query: 38 RVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLE 97 RVL+VG G+G E+ KNL+L G + ++D + + + QFL + VGR++A+ + E Sbjct: 39 RVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKE 98 Query: 98 RAQNLNPMVDVKVDTEDIEKKPE---SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFF 154 P ++ V D P+ FF QF V +R V+++C + Sbjct: 99 SVLQFYPKANI-VAYHDSIMNPDYNVEFFRQFILVMNALDNRAARNHVNRMCLAADVPLI 157 Query: 155 TGDVFGYHG 163 GY G Sbjct: 158 ESGTAGYLG 166 >1YOV-B nrPDB Length = 444 Score = 57.4 bits (137), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 33/110 (30%), Positives = 56/110 (50%), Gaps = 3/110 (2%) Query: 31 QKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRN 90 Q L +VL++G GLG E+ KNL L+G + + ++D + + + QFL R +GR Sbjct: 45 QFLLDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDIGRP 104 Query: 91 RAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDVIV 140 +AE + E + P +V I+ ++F+ QF + C D I+ Sbjct: 105 KAEVAAEFLNDRVPNCNVVPHFNKIQDFNDTFYRQFHII---VCGLDSII 151 >2NVU-B nrPDB Length = 805 Score = 57.4 bits (137), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 33/110 (30%), Positives = 56/110 (50%), Gaps = 3/110 (2%) Query: 31 QKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRN 90 Q L +VL++G GLG E+ KNL L+G + + ++D + + + QFL R +GR Sbjct: 406 QFLLDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDIGRP 465 Query: 91 RAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDVIV 140 +AE + E + P +V I+ ++F+ QF + C D I+ Sbjct: 466 KAEVAAEFLNDRVPNCNVVPHFNKIQDFNDTFYRQFHII---VCGLDSII 512 >1ZFN-A nrPDB Length = 253 Score = 52.8 bits (125), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 34/98 (34%), Positives = 53/98 (54%), Gaps = 2/98 (2%) Query: 9 GGISEEEAAQYDRQIRL--WGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTML 66 G +++ + +Y RQI L L+ Q++L S+VL++GL GLG A L AGV L + Sbjct: 1 GSMNDRDFMRYSRQILLDDIALDGQQKLLDSQVLIIGLGGLGTPAALYLAGAGVGTLVLA 60 Query: 67 DHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNP 104 D + V + Q L T + R +++ S +R LNP Sbjct: 61 DDDDVHLSNLQRQILFTTEDIDRPKSQVSQQRLTQLNP 98 >4RDI-A nrPDB Length = 288 Score = 45.1 bits (105), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 27/100 (27%), Positives = 50/100 (50%) Query: 11 ISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQ 70 IS+ ++ RL+G +A + + + +VG+ G+G+ A+ L G+ +T++D + Sbjct: 25 ISDAWRQRFGGTARLYGEKALQLFADAHICVVGIGGVGSWAAEALARTGIGAITLIDMDD 84 Query: 71 VTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKV 110 V + Q +VG +AE ER + +NP V V Sbjct: 85 VCVTNTNRQIHALRDNVGLAKAEVMAERIRQINPECRVTV 124 >3VH2-A nrPDB Length = 616 Score = 42.4 bits (98), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 21/74 (28%), Positives = 42/74 (56%) Query: 34 LRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAE 93 ++ ++VLL+G LG +++ LI GV+ +T +D+ V+ +P Q L G+ +AE Sbjct: 325 IKNTKVLLLGAGTLGCYVSRALIAWGVRKITFVDNGTVSYSNPVRQALYNFEDCGKPKAE 384 Query: 94 ASLERAQNLNPMVD 107 + + + P++D Sbjct: 385 LAAASLKRIFPLMD 398 >3T7E-A nrPDB Length = 344 Score = 41.6 bits (96), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 21/74 (28%), Positives = 42/74 (56%) Query: 34 LRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAE 93 ++ ++VLL+G LG +++ LI GV+ +T +D+ V+ +P Q L G+ +AE Sbjct: 36 IKNTKVLLLGAGTLGCYVSRALIAWGVRKITFVDNGTVSYSNPVRQALYNFEDCGKPKAE 95 Query: 94 ASLERAQNLNPMVD 107 + + + P++D Sbjct: 96 LAAASLKRIFPLMD 109 >2NMV-A nrPDB Length = 661 Score = 33.9 bits (76), Expect = 0.10, Method: Compositional matrix adjust. Identities = 29/104 (27%), Positives = 47/104 (45%), Gaps = 6/104 (5%) Query: 91 RAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRD-VIVKV----DQI 145 R E +ER + L +VD++ DI+ + +F + D V + SRD V+V D+I Sbjct: 162 RTEMEIERNELLRKLVDIQYARNDIDFQRGTFRVRGDVVEIFPASRDEHCVRVEFFGDEI 221 Query: 146 CHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTKVAKVSQGVE 189 + TG++ G + H FV K+ K Q +E Sbjct: 222 ERIREVDALTGEILGDRDHVAIFPASH-FVTRAEKMEKAIQNIE 264 >3H86-B nrPDB Length = 192 Score = 33.9 bits (76), Expect = 0.10, Method: Compositional matrix adjust. Identities = 34/132 (25%), Positives = 57/132 (43%), Gaps = 12/132 (9%) Query: 67 DHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQF 126 D +Q+ DP Q I+ + GR AE + E V VDT K P+ + Sbjct: 55 DRDQMRKLDPETQKRIQKMA-GRKIAEMAKESP--------VAVDTHSTVKTPKGYLPGL 105 Query: 127 DAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTKVAKVSQ 186 A LT + D+++ V+ + ++ + + T A++ EH+F+ + A +S Sbjct: 106 PAWVLTELNPDIVIVVETDGDEILMRRLSDESRKRDLETTASIEEHQFM---NRAAAMSY 162 Query: 187 GVEDGPDTKRAK 198 GV G K K Sbjct: 163 GVLTGATVKIVK 174 >4H59-A nrPDB Length = 308 Score = 28.9 bits (63), Expect = 3.1, Method: Compositional matrix adjust. Identities = 20/65 (30%), Positives = 29/65 (44%), Gaps = 4/65 (6%) Query: 20 DRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKN----LILAGVKGLTMLDHEQVTPED 75 D+ + W E K L L L GL E N +ILAG G+T D++ ++ Sbjct: 56 DKGVLPWTEEKIKELNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIA 115 Query: 76 PGAQF 80 P A + Sbjct: 116 PVAAY 120 >3FPN-B nrPDB Length = 106 Score = 28.1 bits (61), Expect = 5.3, Method: Composition-based stats. Identities = 22/75 (29%), Positives = 36/75 (48%), Gaps = 5/75 (6%) Query: 91 RAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDV-IVKV----DQI 145 R +ER L +VD++ D DI+ + +F + D V + SRD ++V D+I Sbjct: 18 RVGMEIERNALLRRLVDIQYDRNDIDFRRGTFRVRGDVVEIFPASRDEHCIRVEFFGDEI 77 Query: 146 CHKNSIKFFTGDVFG 160 + TG+V G Sbjct: 78 ERIREVDALTGEVLG 92 >1D9Z-A nrPDB Length = 657 Score = 28.1 bits (61), Expect = 5.9, Method: Compositional matrix adjust. Identities = 30/114 (26%), Positives = 50/114 (43%), Gaps = 7/114 (6%) Query: 91 RAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRD-VIVKV----DQI 145 R +ER L +VD++ D DI+ + +F + D V + SRD ++V D+I Sbjct: 162 RVGMEIERNALLRRLVDIQYDRNDIDFRG-TFRVRGDVVEIFPASRDEHCIRVEFFGDEI 220 Query: 146 CHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTKVAKVSQGVEDGPDTKRAKL 199 + TG V G + H FV + K+ Q +E + + A+L Sbjct: 221 ERIREVDALTGKVLGEREHVAIFPASH-FVTREEKMRLAIQNIEQELEERLAEL 273 >4XGI-A nrPDB Length = 436 Score = 27.3 bits (59), Expect = 9.2, Method: Compositional matrix adjust. Identities = 26/99 (26%), Positives = 41/99 (41%), Gaps = 6/99 (6%) Query: 8 GGGISEEEAAQYDRQIRLWGLEAQKR----LRASRVLLVGLKGLGAEIAKNLILAGVKGL 63 GG + +EA R + + G EA K+ + +R+ + G +G AK AG K + Sbjct: 201 GGSLGRKEAT--GRGVFVVGCEAAKKKGVEIEGARIAVQGFGNVGGIAAKLFQEAGAKVI 258 Query: 64 TMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNL 102 + DH + G VGR A E A+ + Sbjct: 259 AVQDHTGTIHQPAGVDTAKLLDHVGRTGGVAGFEGAEPM 297 >2FOR-A nrPDB Length = 323 Score = 27.3 bits (59), Expect = 10.0, Method: Compositional matrix adjust. Identities = 14/32 (43%), Positives = 19/32 (59%), Gaps = 2/32 (6%) Query: 252 DKGRD--PSSDTYEEDSELLLQIRNDVLDSLG 281 DKGR P D Y E L Q+++D+LD +G Sbjct: 223 DKGRRALPVLDKYAESIGLAFQVQDDILDVVG 254 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6CWZ-C nrPDB 511 e-145 4P22-A nrPDB 397 e-111 1TT5-A nrPDB 212 2e-55 3KYD-B nrPDB 161 3e-40 3KYC-B nrPDB 159 1e-39 2NVU-B nrPDB 159 2e-39 1YOV-B nrPDB 159 2e-39 1JWB-B nrPDB 144 8e-35 1ZFN-A nrPDB 143 1e-34 4RDI-A nrPDB 141 4e-34 3VH2-A nrPDB 99 2e-21 3T7E-A nrPDB 99 2e-21 Sequences not found previously or not previously below threshold: 5FF5-A nrPDB 90 1e-18 3H5A-A nrPDB 86 2e-17 2LZJ-A nrPDB 60 1e-09 5IAA-A nrPDB 52 4e-07 4K28-A nrPDB 38 0.005 5ILO-A nrPDB 34 0.11 6IUM-B nrPDB 34 0.13 3K6J-A nrPDB 32 0.31 5AHK-A nrPDB 32 0.34 2DC1-A nrPDB 32 0.41 1MG5-A nrPDB 30 1.2 5CEE-A nrPDB 30 1.6 3GTY-S nrPDB 30 1.6 1XHK-A nrPDB 30 1.8 1B15-A nrPDB 30 2.0 3K30-A nrPDB 30 2.2 1GPJ-A nrPDB 29 2.3 5ER0-A nrPDB 29 2.3 2O2Z-A nrPDB 29 2.4 3ODG-A nrPDB 29 3.4 2HAE-A nrPDB 29 3.4 6ACQ-A nrPDB 29 4.4 3L1R-A nrPDB 28 5.3 2D0I-A nrPDB 28 5.3 6C6P-A nrPDB 28 6.2 2BXR-A nrPDB 28 6.7 2BC1-A nrPDB 28 7.0 >6CWZ-C nrPDB Length = 346 Score = 511 bits (1315), Expect = e-145, Method: Composition-based stats. Identities = 346/346 (100%), Positives = 346/346 (100%) Query: 1 MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV 60 MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV Sbjct: 1 MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV 60 Query: 61 KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE 120 KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE Sbjct: 61 KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE 120 Query: 121 SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK 180 SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK Sbjct: 121 SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK 180 Query: 181 VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY 240 VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY Sbjct: 181 VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY 240 Query: 241 FLLQVLLKFRTDKGRDPSSDTYEEDSELLLQIRNDVLDSLGISPDLLPEDFVRYCFSEMA 300 FLLQVLLKFRTDKGRDPSSDTYEEDSELLLQIRNDVLDSLGISPDLLPEDFVRYCFSEMA Sbjct: 241 FLLQVLLKFRTDKGRDPSSDTYEEDSELLLQIRNDVLDSLGISPDLLPEDFVRYCFSEMA 300 Query: 301 PVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGMKGNGIVECLGPK 346 PVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGMKGNGIVECLGPK Sbjct: 301 PVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGMKGNGIVECLGPK 346 >4P22-A nrPDB Length = 446 Score = 397 bits (1019), Expect = e-111, Method: Composition-based stats. Identities = 110/398 (27%), Positives = 161/398 (40%), Gaps = 73/398 (18%) Query: 9 GGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDH 68 G ++ + Y RQ+ + G EA KRL+ S VL+ GL+GLG EIAKN+IL GVK +T+ D Sbjct: 52 GSEADIDEGLYSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQ 111 Query: 69 EQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDA 128 D +QF +R +G+NRAE S R LN V V T + E F + F Sbjct: 112 GTAQWADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPLV---EDFLSGFQV 168 Query: 129 VCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANL----------GEHEFVEEK 178 V LT + ++V + CH IK D G G F + GE Sbjct: 169 VVLTNTPLEDQLRVGEFCHNRGIKLVVADTRGLFGQLFCDFGEEMILTDSNGEQPLSAMV 228 Query: 179 TKVAKVSQGVEDGPDTKRAKLDSSE----------------------------------- 203 + V K + GV D R +S + Sbjct: 229 SMVTKDNPGVVTCLDEARHGFESGDFVSFSEVQGMVELNGNQPMEIKVLGPYTFSICDTS 288 Query: 204 ------------TTMVKKKVVFCPVKEAL-EVDWSSEKAKAALKRTTSDYFLLQVLLKFR 250 V KK+ F + +L E D+ A R + Q L +F Sbjct: 289 NFSDYIRGGIVSQVKVPKKISFKSLVASLAEPDFVVTDF-AKFSRPAQLHIGFQALHQFC 347 Query: 251 TDKGRDPSSDTYEEDSELLLQIRNDVLDSL-GISPDLLPEDFVR----YCFSEMAPVCAV 305 GR P E+ +EL+ + +L + + L ED +R ++AP+ A Sbjct: 348 AQHGRPPRPRNDEDAAELVALAQAVNARALPAVQQNNLDEDLIRKLAYVAAGDLAPINAF 407 Query: 306 VGGILAQEIVKALSQRDPPHNNFFFFDGMKGNGIVECL 343 +GG+ AQE++KA S + P + +FD + ECL Sbjct: 408 IGGLAAQEVMKACSGKFMPIMQWLYFDAL------ECL 439 >1TT5-A nrPDB Length = 531 Score = 212 bits (540), Expect = 2e-55, Method: Composition-based stats. Identities = 69/267 (25%), Positives = 117/267 (43%), Gaps = 14/267 (5%) Query: 17 AQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDP 76 +YDRQ+RLWG Q+ L ++ V L+ G EI KNL+L G+ T++D QV+ ED Sbjct: 13 QKYDRQLRLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDA 72 Query: 77 GAQFLIRTGSVGRNRAEASLERAQNLNPMVD---VKVDTEDIEKKPESFFTQFDAVCLTC 133 G F ++ S+G+NRAEA++E Q LN V V+ E++ SFF +F V T Sbjct: 73 GNNFFLQRSSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVATQ 132 Query: 134 CSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTKVAKVSQGVEDGPD 193 +++ + + I +G GY + EH +E A ++ Sbjct: 133 LPESTSLRLADVLWNSQIPLLICRTYGLVGYMRIIIKEHPVIESHPDNALEDLRLDKPFP 192 Query: 194 TKRAKLDSSETTMVKKK----VVFCPVKEALEVDWSSEKAKAALKRTTSDYFLLQVLLKF 249 R S + ++KK + + W SE + +T + + L++ Sbjct: 193 ELREHFQSYDLDHMEKKDHSHTPWIVIIAKYLAQWYSET-NGRIPKTYKEKEDFRDLIR- 250 Query: 250 RTDKG--RDPSSDTYEEDSELLLQIRN 274 +G + + +EE + + N Sbjct: 251 ---QGILKPEDEENFEEAIKNVNTALN 274 Score = 143 bits (360), Expect = 1e-34, Method: Composition-based stats. Identities = 56/286 (19%), Positives = 102/286 (35%), Gaps = 30/286 (10%) Query: 72 TPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFT------- 124 D Q +++ E E +N+N ++ IE Sbjct: 244 DFRDLIRQGILKPED-----EENFEEAIKNVNTALNTTQIPSSIEDIFNDDRCINITKQT 298 Query: 125 -QFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGY--HGYTFANLGEHEFVEEKTKV 181 F + + + +I D Y + + + V Sbjct: 299 PSFWILARALKEFVAKEGQGNLPVRGTIPDMIADSGKYIKLQNVYREKAKKDAAAVGNHV 358 Query: 182 AKVSQGVEDGPD---TKRAKLDSSETTMVKKKVVFC-PVKEALEVDWSSEK-AKAALKRT 236 AK+ Q + P+ K KL S + + +VV C + E +D ++ +++ Sbjct: 359 AKLLQSIGQAPESISEKELKLLCSNSAFL--RVVRCRSLAEEYGLDTINKDEIISSMDNP 416 Query: 237 TS---DYFLLQVLLKFRTDKGRDPSSDTY--EEDSELLLQIRNDVLDSLGIS---PDLLP 288 + Y +L+ + +F +GR P Y EED L L G+S D Sbjct: 417 DNEIVLYLMLRAVDRFHKQQGRYPGVSNYQVEEDIGKLKSCLTGFLQEYGLSVMVKDDYV 476 Query: 289 EDFVRYCFSEMAPVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGM 334 +F RY +E + A +GG AQE++K ++++ NN + + GM Sbjct: 477 HEFCRYGAAEPHTIAAFLGGAAAQEVIKIITKQFVIFNNTYIYSGM 522 >3KYD-B nrPDB Length = 551 Score = 161 bits (408), Expect = 3e-40, Method: Composition-based stats. Identities = 37/137 (27%), Positives = 62/137 (45%), Gaps = 4/137 (2%) Query: 32 KRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNR 91 + + RVL+VG G+G E+ KNL+L G + ++D + + + QFL + VGR++ Sbjct: 15 EAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVGRSK 74 Query: 92 AEASLERAQNLNPMVDVKVDTEDIEKKPE---SFFTQFDAVCLTCCSRDVIVKVDQICHK 148 A+ + E P ++ V D P+ FF QF V +R V+++C Sbjct: 75 AQVAKESVLQFYPKANI-VAYHDSIMNPDYNVEFFRQFILVMNALDNRAARNHVNRMCLA 133 Query: 149 NSIKFFTGDVFGYHGYT 165 + GY G Sbjct: 134 ADVPLIESGTAGYLGQV 150 >3KYC-B nrPDB Length = 660 Score = 159 bits (403), Expect = 1e-39, Method: Composition-based stats. Identities = 37/137 (27%), Positives = 62/137 (45%), Gaps = 4/137 (2%) Query: 32 KRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNR 91 + + RVL+VG G+G E+ KNL+L G + ++D + + + QFL + VGR++ Sbjct: 33 EAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVGRSK 92 Query: 92 AEASLERAQNLNPMVDVKVDTEDIEKKPE---SFFTQFDAVCLTCCSRDVIVKVDQICHK 148 A+ + E P ++ V D P+ FF QF V +R V+++C Sbjct: 93 AQVAKESVLQFYPKANI-VAYHDSIMNPDYNVEFFRQFILVMNALDNRAARNHVNRMCLA 151 Query: 149 NSIKFFTGDVFGYHGYT 165 + GY G Sbjct: 152 ADVPLIESGTAGYLGQV 168 >2NVU-B nrPDB Length = 805 Score = 159 bits (401), Expect = 2e-39, Method: Composition-based stats. Identities = 59/325 (18%), Positives = 112/325 (34%), Gaps = 57/325 (17%) Query: 31 QKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRN 90 Q L +VL++G GLG E+ KNL L+G + + ++D + + + QFL R +GR Sbjct: 406 QFLLDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDIGRP 465 Query: 91 RAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDVIVKVDQICH--- 147 +AE + E + P +V I+ ++F+ QF + S ++ + Sbjct: 466 KAEVAAEFLNDRVPNCNVVPHFNKIQDFNDTFYRQFHIIVCGLDSIIARRWINGMLISLL 525 Query: 148 ---------KNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTKVAKVSQGVEDGPDTKRAK 198 + + G G+ G L G+ + Sbjct: 526 NYEDGVLDPSSIVPLIDGGTEGFKGNARVIL----------------PGMTACIECTLE- 568 Query: 199 LDSSETTMVKKKVVF--CPVKEALEVDWSSEKAKAALKRTTSDYFLLQVLLKFRTDKGRD 256 + +V F C + A++ R +L++ ++ Sbjct: 569 -------LYPPQVNFPMCTI--------------ASMPRLPEHCIEYVRMLQWPKEQPFG 607 Query: 257 PSSDTYEEDSELLLQIRNDVLD---SLGISPDLL--PEDFVRYCFSEMAPVCAVVGGILA 311 +D E + I L+ I + V+ +A AV+ + A Sbjct: 608 EGVPLDGDDPEHIQWIFQKSLERASQYNIRGVTYRLTQGVVKRIIPAVASTNAVIAAVCA 667 Query: 312 QEIVKALSQRDPPHNNFFFFDGMKG 336 E+ K + P NN+ F+ + G Sbjct: 668 TEVFKIATSAYIPLNNYLVFNDVDG 692 >1YOV-B nrPDB Length = 444 Score = 159 bits (401), Expect = 2e-39, Method: Composition-based stats. Identities = 59/325 (18%), Positives = 112/325 (34%), Gaps = 57/325 (17%) Query: 31 QKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRN 90 Q L +VL++G GLG E+ KNL L+G + + ++D + + + QFL R +GR Sbjct: 45 QFLLDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDIGRP 104 Query: 91 RAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDVIVKVDQICH--- 147 +AE + E + P +V I+ ++F+ QF + S ++ + Sbjct: 105 KAEVAAEFLNDRVPNCNVVPHFNKIQDFNDTFYRQFHIIVCGLDSIIARRWINGMLISLL 164 Query: 148 ---------KNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTKVAKVSQGVEDGPDTKRAK 198 + + G G+ G L G+ + Sbjct: 165 NYEDGVLDPSSIVPLIDGGTEGFKGNARVIL----------------PGMTACIECTLE- 207 Query: 199 LDSSETTMVKKKVVF--CPVKEALEVDWSSEKAKAALKRTTSDYFLLQVLLKFRTDKGRD 256 + +V F C + A++ R +L++ ++ Sbjct: 208 -------LYPPQVNFPMCTI--------------ASMPRLPEHCIEYVRMLQWPKEQPFG 246 Query: 257 PSSDTYEEDSELLLQIRNDVLD---SLGISPDLL--PEDFVRYCFSEMAPVCAVVGGILA 311 +D E + I L+ I + V+ +A AV+ + A Sbjct: 247 EGVPLDGDDPEHIQWIFQKSLERASQYNIRGVTYRLTQGVVKRIIPAVASTNAVIAAVCA 306 Query: 312 QEIVKALSQRDPPHNNFFFFDGMKG 336 E+ K + P NN+ F+ + G Sbjct: 307 TEVFKIATSAYIPLNNYLVFNDVDG 331 >1JWB-B nrPDB Length = 249 Score = 144 bits (362), Expect = 8e-35, Method: Composition-based stats. Identities = 43/159 (27%), Positives = 76/159 (47%), Gaps = 5/159 (3%) Query: 11 ISEEEAAQYDRQIRLWGLE--AQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDH 68 +S++E +Y+RQI L G + Q+ L+ SRVL+VGL GLG ++ L AGV LT+LD Sbjct: 4 LSDQEMLRYNRQIILRGFDFDGQEALKDSRVLIVGLGGLGCAASQYLASAGVGNLTLLDF 63 Query: 69 EQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE--SFFTQF 126 + V+ + Q L +VG+ + E++ + +NP + + + E + + Sbjct: 64 DTVSLSNLQRQTLHSDATVGQPKVESARDALTRINPHIAITP-VNALLDDAELAALIAEH 122 Query: 127 DAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYT 165 D V + V +++ C + +G G Sbjct: 123 DLVLDCTDNVAVRNQLNAGCFAAKVPLVSGAAIRMEGQI 161 >1ZFN-A nrPDB Length = 253 Score = 143 bits (360), Expect = 1e-34, Method: Composition-based stats. Identities = 40/162 (24%), Positives = 72/162 (44%), Gaps = 3/162 (1%) Query: 9 GGISEEEAAQYDRQIRL--WGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTML 66 G +++ + +Y RQI L L+ Q++L S+VL++GL GLG A L AGV L + Sbjct: 1 GSMNDRDFMRYSRQILLDDIALDGQQKLLDSQVLIIGLGGLGTPAALYLAGAGVGTLVLA 60 Query: 67 DHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKP-ESFFTQ 125 D + V + Q L T + R +++ S +R LNP + + + + + + + Sbjct: 61 DDDDVHLSNLQRQILFTTEDIDRPKSQVSQQRLTQLNPDIQLTALQQRLTGEALKDAVAR 120 Query: 126 FDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFA 167 D V + +++ C + T G+ G Sbjct: 121 ADVVLDCTDNMATRQEINAACVALNTPLITASAVGFGGQLMV 162 >4RDI-A nrPDB Length = 288 Score = 141 bits (356), Expect = 4e-34, Method: Composition-based stats. Identities = 34/152 (22%), Positives = 64/152 (42%), Gaps = 2/152 (1%) Query: 11 ISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQ 70 IS+ ++ RL+G +A + + + +VG+ G+G+ A+ L G+ +T++D + Sbjct: 25 ISDAWRQRFGGTARLYGEKALQLFADAHICVVGIGGVGSWAAEALARTGIGAITLIDMDD 84 Query: 71 VTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIE-KKPESFFT-QFDA 128 V + Q +VG +AE ER + +NP V V + + + + + Sbjct: 85 VCVTNTNRQIHALRDNVGLAKAEVMAERIRQINPECRVTVVDDFVTPDNVAQYMSVGYSY 144 Query: 129 VCLTCCSRDVIVKVDQICHKNSIKFFTGDVFG 160 V S + C +N I T G Sbjct: 145 VIDAIDSVRPKAALIAYCRRNKIPLVTTGGAG 176 >3VH2-A nrPDB Length = 616 Score = 99.4 bits (246), Expect = 2e-21, Method: Composition-based stats. Identities = 22/86 (25%), Positives = 44/86 (51%) Query: 24 RLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIR 83 R+ ++ ++VLL+G LG +++ LI GV+ +T +D+ V+ +P Q L Sbjct: 315 RILPDLNLDIIKNTKVLLLGAGTLGCYVSRALIAWGVRKITFVDNGTVSYSNPVRQALYN 374 Query: 84 TGSVGRNRAEASLERAQNLNPMVDVK 109 G+ +AE + + + P++D Sbjct: 375 FEDCGKPKAELAAASLKRIFPLMDAT 400 >3T7E-A nrPDB Length = 344 Score = 99.4 bits (246), Expect = 2e-21, Method: Composition-based stats. Identities = 22/86 (25%), Positives = 44/86 (51%) Query: 24 RLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIR 83 R+ ++ ++VLL+G LG +++ LI GV+ +T +D+ V+ +P Q L Sbjct: 26 RILPDLNLDIIKNTKVLLLGAGTLGCYVSRALIAWGVRKITFVDNGTVSYSNPVRQALYN 85 Query: 84 TGSVGRNRAEASLERAQNLNPMVDVK 109 G+ +AE + + + P++D Sbjct: 86 FEDCGKPKAELAAASLKRIFPLMDAT 111 >5FF5-A nrPDB Length = 381 Score = 90.2 bits (222), Expect = 1e-18, Method: Composition-based stats. Identities = 35/112 (31%), Positives = 58/112 (51%), Gaps = 9/112 (8%) Query: 11 ISEEEAAQYDRQIRLWGL-EA--------QKRLRASRVLLVGLKGLGAEIAKNLILAGVK 61 +S EE +Y+RQI + L +A Q+RL+ S+V + G+ G G A L ++G+ Sbjct: 98 LSGEEVERYNRQILQFSLIDADNQHPFVYQERLKQSKVAIFGMGGWGTWCALQLAMSGIG 157 Query: 62 GLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTE 113 L ++D + V + Q L RT VG+N+ +A+ + N V V+ E Sbjct: 158 TLRLIDGDDVELSNINRQVLYRTDDVGKNKVDAAKDTILAYNENVHVETFFE 209 >3H5A-A nrPDB Length = 358 Score = 85.9 bits (211), Expect = 2e-17, Method: Composition-based stats. Identities = 30/158 (18%), Positives = 64/158 (40%), Gaps = 16/158 (10%) Query: 12 SEEEAAQYDRQIRLWGLEA------QKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTM 65 + E +Y R + Q +L+ ++V+++G G+G ++ L +G+ + + Sbjct: 85 NSTENNRYSRNFLHYQSYGANPVLVQDKLKNAKVVILGCGGIGNHVSVILATSGIGEIIL 144 Query: 66 LDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKV------DTEDIEKKP 119 +D++Q+ + Q L VG+N+ E N + V D D+ K P Sbjct: 145 IDNDQIENTNLTRQVLFSEDDVGKNKTEVIKRELLKRNSEISVSEIALNINDYTDLHKVP 204 Query: 120 ESFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGD 157 E+ V ++I V++ C + + + Sbjct: 205 EA----DIWVVSADHPFNLINWVNKYCVRANQPYINAG 238 Score = 31.2 bits (69), Expect = 0.75, Method: Composition-based stats. Identities = 11/59 (18%), Positives = 23/59 (38%), Gaps = 4/59 (6%) Query: 271 QIRNDVLDSLGISPDLLPEDF----VRYCFSEMAPVCAVVGGILAQEIVKALSQRDPPH 325 + + V D G + + R+ + APV V + A +++K + + P Sbjct: 259 ECQKVVADLYGSEKENIDHKIKLINSRFKPATFAPVNNVAAALCAADVIKFIGKYSEPL 317 >2LZJ-A nrPDB Length = 112 Score = 60.1 bits (144), Expect = 1e-09, Method: Composition-based stats. Identities = 13/98 (13%), Positives = 21/98 (21%), Gaps = 47/98 (47%) Query: 170 GEHEFVEEKTKVAKVSQGVEDGPDTKRAKLDSSE-------------------------- 203 GE + V K + GV D R ++ + Sbjct: 13 GEQPLSAMVSMVTKDNPGVVTCLDEARHGFETGDFVSFSEVQGMIQLNGCQPMEIKVLGP 72 Query: 204 ---------------------TTMVKKKVVFCPVKEAL 220 V KK+ F + +L Sbjct: 73 YTFSICDTSNFSDYIRGGIVSQVKVPKKISFKSLPASL 110 >5IAA-A nrPDB Length = 290 Score = 52.0 bits (123), Expect = 4e-07, Method: Composition-based stats. Identities = 25/140 (17%), Positives = 59/140 (42%), Gaps = 14/140 (10%) Query: 32 KRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNR 91 +++R V +VG+ G+G+ A+ L G+ L + D+++V + + G ++ Sbjct: 13 EKIRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANMNR-LFFQPHQAGLSK 71 Query: 92 AEASLERAQNLNPMVDVKVDTEDI--EKKPESFFTQF-----------DAVCLTCCSRDV 138 +A+ +N+NP V +V +I + + F + D V + + Sbjct: 72 VQAAEHTLRNINPDVLFEVHNYNITTVENFQHFMDRISNGGLEEGKPVDLVLSCVDNFEA 131 Query: 139 IVKVDQICHKNSIKFFTGDV 158 + ++ C++ + V Sbjct: 132 RMTINTACNELGQTWMESGV 151 >4K28-A nrPDB Length = 269 Score = 38.1 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 21/83 (25%), Positives = 35/83 (42%), Gaps = 15/83 (18%) Query: 1 MVEKEEAGGGISEEEAAQYDRQIRLWGL--EAQKRLRASR----------VLLVGLKGLG 48 + E+ A G I+ + +R RL G + L A+ L++G G+G Sbjct: 81 LSERAAALGSIN---VIRRERDGRLLGDNVDGAGFLGAAHKHGFEPAGKRALVIGCGGVG 137 Query: 49 AEIAKNLILAGVKGLTMLDHEQV 71 + IA L AG+ +T+ D Sbjct: 138 SAIAYALAEAGIASITLCDPSTA 160 >5ILO-A nrPDB Length = 271 Score = 33.9 bits (76), Expect = 0.11, Method: Composition-based stats. Identities = 18/90 (20%), Positives = 36/90 (40%), Gaps = 8/90 (8%) Query: 39 VLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQ-------VTPEDPGAQFLIRTGSVGRNR 91 V+ G G+G +++K L+ AG + ++D + + P +I V + Sbjct: 19 VVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAAHPTQSVMIIKMDVANKK 78 Query: 92 -AEASLERAQNLNPMVDVKVDTEDIEKKPE 120 EA+ E +D+ V+ I + Sbjct: 79 GVEATYEEIAKTFGNIDIVVNVAGIFNDKD 108 >6IUM-B nrPDB Length = 701 Score = 33.5 bits (75), Expect = 0.13, Method: Composition-based stats. Identities = 31/204 (15%), Positives = 72/204 (35%), Gaps = 12/204 (5%) Query: 38 RVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLE 97 +V ++G +G I+ N + AG+ +T+L+ +Q + + + + + + E Sbjct: 294 KVAVIGAGTMGGGISMNFLNAGI-PVTILETKQEALDRGVGIIRKNYENSAK-KGKLTQE 351 Query: 98 RAQNLNPMVDVKVDTEDIEKKP---ESFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFF 154 + + ++ + +D++ E+ F + D + K I N+ Sbjct: 352 KVEQRMGLLSTTLSYDDLKDADLIIEAVFEEMGVKETVFKKLDEVAKQGAILASNTSTLD 411 Query: 155 TGDVFGYHGYTFANLGEHEFV-EEKTKVAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVF 213 + + +G H F K+ +V +G + G D + V KK+ Sbjct: 412 VNKIASFTKRPQDVVGMHFFSPANVMKLLEVVRGEKTGKDVL------ATVMQVGKKIKK 465 Query: 214 CPVKEALEVDWSSEKAKAALKRTT 237 V + + + R Sbjct: 466 TAVVSGVCDGFIGNRMIEQYSRQA 489 >3K6J-A nrPDB Length = 460 Score = 32.4 bits (72), Expect = 0.31, Method: Composition-based stats. Identities = 15/107 (14%), Positives = 43/107 (40%), Gaps = 11/107 (10%) Query: 10 GISEEEAAQYDRQIRLWGLEA-QKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDH 68 ++ + + DR G + + V ++G +G +A LAG++ ++ + Sbjct: 32 SLAGQWSLPNDR-----GDHTNSEAYDVNSVAIIGGGTMGKAMAICFGLAGIETFLVVRN 86 Query: 69 EQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDI 115 EQ ++ + + ++ + +R + +N + + D + Sbjct: 87 EQRCKQEL--EVMYARE---KSFKRLNDKRIEKINANLKITSDFHKL 128 >5AHK-A nrPDB Length = 588 Score = 32.4 bits (72), Expect = 0.34, Method: Composition-based stats. Identities = 26/126 (20%), Positives = 44/126 (34%), Gaps = 14/126 (11%) Query: 7 AGGGISEEEAAQYDRQIRLWG------LEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV 60 GG ++ ++ QI L G L+ ++++AS + L L G A + + Sbjct: 238 GGGAVNSSGFQKWLEQIELRGIPYVASLKGAEKIKASDLYLGMLGAYGTRAANHAVQNCD 297 Query: 61 KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE 120 L + V Q + RN AE Q V D + E Sbjct: 298 LLLVLGSRMDV------RQTGAQPEDFARN-AEIIQIDLQEGQLNNRVIADFSYQIELSE 350 Query: 121 SFFTQF 126 +F++F Sbjct: 351 -YFSRF 355 >2DC1-A nrPDB Length = 236 Score = 32.0 bits (71), Expect = 0.41, Method: Composition-based stats. Identities = 34/152 (22%), Positives = 55/152 (36%), Gaps = 24/152 (15%) Query: 39 VLLVGLKGLGAEIAKNLILAGVKGLTMLD--HEQVTPEDPGAQFLIRTGSVGRNRAEASL 96 V L+G +G +A+ L G + +LD E +FL R V EA+ Sbjct: 3 VGLIGYGAIGKFLAEWLERNGFEIAAILDVRGEHEKMVRGIDEFLQREMDVA---VEAAS 59 Query: 97 ERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTC---CSRDVIVKVDQICHKNSIKF 153 ++ VK E I K D + L+ RD + +V ++C K + Sbjct: 60 QQ--------AVKDYAEKILK------AGIDLIVLSTGAFADRDFLSRVREVCRKTGRRV 105 Query: 154 FTGDVFGYHGYTFANLGEHEFVEEKTKVAKVS 185 + G G A E +EE + + Sbjct: 106 YIAS--GAIGGLDAIFSASELIEEIVLTTRKN 135 >1MG5-A nrPDB Length = 255 Score = 30.4 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 32/77 (41%), Gaps = 21/77 (27%) Query: 39 VLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLER 98 + + GL G+G + +K L+ +K L +LD E+P A++ Sbjct: 10 IFVAGLGGIGLDTSKELLKRDLKNLVILD----RIENP-----------------AAIAE 48 Query: 99 AQNLNPMVDVKVDTEDI 115 + +NP V V D+ Sbjct: 49 LKAINPKVTVTFYPYDV 65 >5CEE-A nrPDB Length = 413 Score = 30.1 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 11/37 (29%), Positives = 20/37 (54%) Query: 31 QKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLD 67 +K + +V++ G G IAK L+L V + ++D Sbjct: 202 KKSIEDVQVVINGAGSAGMAIAKMLLLLKVNNVVLVD 238 >3GTY-S nrPDB Length = 149 Score = 30.1 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 17/108 (15%), Positives = 36/108 (33%), Gaps = 6/108 (5%) Query: 142 VDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTKVAKVSQGVEDGPDTKRAKLDS 201 ++++ V+G + + V V +E P +R Sbjct: 20 INRVMWDGKKTIAQKIVYGAFDIIREKTKKDPLEVFRQAVENVKPVLEVRP--RRVG--- 74 Query: 202 SETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDYFLLQVLLKF 249 T V +V P + +L + W E A+A R + +++ + Sbjct: 75 GATYQVPIEVQ-EPRRTSLALRWIVEAARAKKGRPMKEKLAEEIIAAY 121 >1XHK-A nrPDB Length = 187 Score = 29.7 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 21/148 (14%), Positives = 46/148 (31%), Gaps = 14/148 (9%) Query: 55 LILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTED 114 L G+ +T + + + ++PG L +G + ++ + ++ L + + +D Sbjct: 15 LGAGGIGDVTKIIVQILESKNPGTHLLNISGDIAKHSITLASALSKKLVAEKKLPLPKKD 74 Query: 115 IEKKPESFFTQFDAVCLTCCSRDVIVKVDQICHKN--SIKFFTGDVFGYHGYTFANLGEH 172 I+ + + QF V I FA G Sbjct: 75 IDLNNKEIYIQFSQSYSKIDGDSATAAVCLAIISALLDIPL---------KQDFAITGSL 125 Query: 173 EFVEEKTKVAKVSQGVEDGPDTKRAKLD 200 + + V++ +E KR Sbjct: 126 DLSGNVLAIGGVNEKIEAA---KRYGFK 150 >1B15-A nrPDB Length = 254 Score = 29.7 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 15/77 (19%), Positives = 31/77 (40%), Gaps = 21/77 (27%) Query: 39 VLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLER 98 + + L G+G + ++ L+ +K +LD E+P +L Sbjct: 9 IFVAALGGIGLDTSRELVKRNLKNFVILD----RVENP-----------------TALAE 47 Query: 99 AQNLNPMVDVKVDTEDI 115 + +NP V++ T D+ Sbjct: 48 LKAINPKVNITFHTYDV 64 >3K30-A nrPDB Length = 690 Score = 29.7 bits (65), Expect = 2.2, Method: Composition-based stats. Identities = 16/57 (28%), Positives = 27/57 (47%), Gaps = 9/57 (15%) Query: 10 GISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTML 66 + EE + + R+ E+ +RVL+VG G E A+ L GV+G ++ Sbjct: 371 SMGEEWRRGWHPE-RIRAKES-----DARVLVVGAGPSGLEAARAL---GVRGYDVV 418 >1GPJ-A nrPDB Length = 404 Score = 29.3 bits (64), Expect = 2.3, Method: Composition-based stats. Identities = 11/42 (26%), Positives = 20/42 (47%) Query: 26 WGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLD 67 L VL+VG +G +AK+L+ GV+ + + + Sbjct: 157 LAERELGSLHDKTVLVVGAGEMGKTVAKSLVDRGVRAVLVAN 198 >5ER0-A nrPDB Length = 518 Score = 29.3 bits (64), Expect = 2.3, Method: Composition-based stats. Identities = 11/43 (25%), Positives = 22/43 (51%), Gaps = 5/43 (11%) Query: 29 EAQKRLRAS----RVLLVGLKGLGAEIAKNLILAGVKGLTMLD 67 AQ + + R+ ++G +GAE+A+ G +T++D Sbjct: 186 HAQALIEDAKEAKRITVIGAGYIGAELAEAYSTTG-HDVTLID 227 >2O2Z-A nrPDB Length = 323 Score = 29.3 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 8/32 (25%), Positives = 18/32 (56%) Query: 29 EAQKRLRASRVLLVGLKGLGAEIAKNLILAGV 60 E + +R + V+++G L + NL++ G+ Sbjct: 171 EGLEAIRKADVIVIGPGSLYTSVLPNLLVPGI 202 >3ODG-A nrPDB Length = 287 Score = 28.9 bits (63), Expect = 3.4, Method: Composition-based stats. Identities = 21/118 (17%), Positives = 39/118 (33%), Gaps = 4/118 (3%) Query: 76 PGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCS 135 G +FL T + G R E L ++ T + + F +F ++ Sbjct: 115 MGCEFLFCTNAAGSLRPEVLPGSVVMLKDHINTMPGTPLVGPNDDRFGPRFFSLANAYD- 173 Query: 136 RDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTKVAKVSQGVEDGPD 193 +D+ + +I + I G Y G F E + + G+ P+ Sbjct: 174 KDLRADMAKIAQQLDIPLTEGVFVSYPGPCFETPAE---IRMMQIIGGDVVGMSVVPE 228 >2HAE-A nrPDB Length = 386 Score = 28.9 bits (63), Expect = 3.4, Method: Composition-based stats. Identities = 12/45 (26%), Positives = 25/45 (55%) Query: 31 QKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPED 75 +K++ +V++ G+ G I K L+ GVK + +D + + E+ Sbjct: 177 EKKIEEVKVVVNGIGAAGYNIVKFLLDLGVKNVVAVDRKGILNEN 221 >6ACQ-A nrPDB Length = 302 Score = 28.5 bits (62), Expect = 4.4, Method: Composition-based stats. Identities = 6/23 (26%), Positives = 12/23 (52%) Query: 38 RVLLVGLKGLGAEIAKNLILAGV 60 +V ++G +G+ IA+ G Sbjct: 23 KVCVIGAGTMGSGIAQAFAAKGF 45 >3L1R-A nrPDB Length = 478 Score = 28.1 bits (61), Expect = 5.3, Method: Composition-based stats. Identities = 20/86 (23%), Positives = 32/86 (37%), Gaps = 3/86 (3%) Query: 38 RVLLVGLKGLGAEIAKNLILAGVKGLTMLD-HEQVTPEDPGAQFLIRTGSVGRNRAEASL 96 RV++VG G AK L AG+ L +L+ + + F +G N E Sbjct: 6 RVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGINVELGANWVEGVN 65 Query: 97 ERAQNLNPMVDVKVDTEDIEKKPESF 122 +NP+ + T + F Sbjct: 66 G--GKMNPIWPIVNSTLKLRNFRSDF 89 >2D0I-A nrPDB Length = 333 Score = 28.1 bits (61), Expect = 5.3, Method: Composition-based stats. Identities = 13/47 (27%), Positives = 26/47 (55%), Gaps = 1/47 (2%) Query: 16 AAQYDRQIRLW-GLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVK 61 +++ ++W G + + L +V ++G+ +G IA+ LI GVK Sbjct: 125 RGEWESHAKIWTGFKRIESLYGKKVGILGMGAIGKAIARRLIPFGVK 171 >6C6P-A nrPDB Length = 458 Score = 28.1 bits (61), Expect = 6.2, Method: Composition-based stats. Identities = 12/46 (26%), Positives = 24/46 (52%), Gaps = 1/46 (2%) Query: 36 ASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFL 81 V++VG LG+ +A L G + +T+++ + P+ +FL Sbjct: 7 DPEVIIVGAGVLGSALAAVLSRDG-RKVTVIERDLKEPDRIVGEFL 51 >2BXR-A nrPDB Length = 527 Score = 27.7 bits (60), Expect = 6.7, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 26/74 (35%), Gaps = 1/74 (1%) Query: 39 VLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTP-EDPGAQFLIRTGSVGRNRAEASLE 97 V+++G G AK L GV L + ++V + VG + Sbjct: 16 VVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHVDYVDVGGAYVGPTQN 75 Query: 98 RAQNLNPMVDVKVD 111 R L+ + ++ Sbjct: 76 RILRLSKELGIETY 89 >2BC1-A nrPDB Length = 490 Score = 27.7 bits (60), Expect = 7.0, Method: Composition-based stats. Identities = 10/37 (27%), Positives = 17/37 (45%), Gaps = 1/37 (2%) Query: 38 RVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPE 74 RV +VG +G E+A+ G K + ++D Sbjct: 196 RVAVVGAGYIGVELAEAFQRKG-KEVVLIDVVDTCLA 231 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.313 0.131 0.321 Lambda K H 0.267 0.0398 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,395,449 Number of Sequences: 36641 Number of extensions: 409376 Number of successful extensions: 1426 Number of sequences better than 10.0: 42 Number of HSP's better than 10.0 without gapping: 41 Number of HSP's successfully gapped in prelim test: 24 Number of HSP's that attempted gapping in prelim test: 1356 Number of HSP's gapped (non-prelim): 80 length of query: 346 length of database: 10,336,785 effective HSP length: 98 effective length of query: 248 effective length of database: 6,745,967 effective search space: 1672999816 effective search space used: 1672999816 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 59 (27.4 bits)