BLASTP 2.2.23 [Feb-03-2010]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Altschul, Stephen F.,
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= Q9SUM3
(711 letters)
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
36,641 sequences; 10,336,785 total letters
Searching..................................................done
Results from round 1
Score E
Sequences producing significant alignments: (bits) Value
5GXU-A nrPDB 1335 0.0
6J79-A nrPDB 454 e-128
3ES9-A nrPDB 453 e-127
3QFR-A nrPDB 450 e-126
3FJO-A nrPDB 405 e-113
2BN4-A nrPDB 294 1e-79
1TLL-A nrPDB 248 5e-66
6EFV-A nrPDB 231 8e-61
1B1C-A nrPDB 127 1e-29
1BVY-F nrPDB 70 4e-12
4H2D-A nrPDB 67 4e-11
2B5O-A nrPDB 66 6e-11
3HR4-A nrPDB 63 3e-10
1YKG-A nrPDB 57 2e-08
2M6S-A nrPDB 44 3e-04
5LJI-A nrPDB 42 7e-04
4HEQ-A nrPDB 39 0.007
5V57-A nrPDB 38 0.020
2HNA-A nrPDB 37 0.025
2FCR-A nrPDB 37 0.038
4OXX-A nrPDB 37 0.040
5XRA-A nrPDB 36 0.059
6GAQ-A nrPDB 36 0.066
5ZKP-A nrPDB 35 0.12
3F6S-A nrPDB 33 0.34
2V5U-A nrPDB 33 0.35
1AG9-A nrPDB 33 0.53
1CZN-A nrPDB 33 0.60
1KRH-A nrPDB 33 0.61
5F1Q-A nrPDB 32 1.2
5YOB-A nrPDB 32 1.3
3KAQ-A nrPDB 31 1.5
5OGX-A nrPDB 31 1.5
1DPE-A nrPDB 31 1.8
4U9U-A nrPDB 31 1.8
4W5W-A nrPDB 31 1.9
2YXG-A nrPDB 31 2.1
5IM2-A nrPDB 30 2.8
4EH1-A nrPDB 30 3.3
4P6V-F nrPDB 30 4.4
3OZU-A nrPDB 29 5.8
3R0X-A nrPDB 29 6.2
3SS9-X nrPDB 29 7.3
3WBE-A nrPDB 28 9.4
>5GXU-A nrPDB
Length = 640
Score = 1335 bits (3456), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 639/639 (100%), Positives = 639/639 (100%)
Query: 73 RRSGSGNSKRVEPLKPLVIKPREEEIDDGRKKVTIFFGTQTGTAEGFAKALGEEAKARYE 132
RRSGSGNSKRVEPLKPLVIKPREEEIDDGRKKVTIFFGTQTGTAEGFAKALGEEAKARYE
Sbjct: 2 RRSGSGNSKRVEPLKPLVIKPREEEIDDGRKKVTIFFGTQTGTAEGFAKALGEEAKARYE 61
Query: 133 KTRFKIVDLDDYAADDDEYEEKLKKEDVAFFFLATYGDGEPTDNAARFYKWFTEGNDRGE 192
KTRFKIVDLDDYAADDDEYEEKLKKEDVAFFFLATYGDGEPTDNAARFYKWFTEGNDRGE
Sbjct: 62 KTRFKIVDLDDYAADDDEYEEKLKKEDVAFFFLATYGDGEPTDNAARFYKWFTEGNDRGE 121
Query: 193 WLKNLKYGVFGLGNRQYEHFNKVAKVVDDILVEQGAQRLVQVGLGDDDQCIEDDFTAWRE 252
WLKNLKYGVFGLGNRQYEHFNKVAKVVDDILVEQGAQRLVQVGLGDDDQCIEDDFTAWRE
Sbjct: 122 WLKNLKYGVFGLGNRQYEHFNKVAKVVDDILVEQGAQRLVQVGLGDDDQCIEDDFTAWRE 181
Query: 253 ALWPELDTILREEGDTAVATPYTAAVLEYRVSIHDSEDAKFNDINMANGNGYTVFDAQHP 312
ALWPELDTILREEGDTAVATPYTAAVLEYRVSIHDSEDAKFNDINMANGNGYTVFDAQHP
Sbjct: 182 ALWPELDTILREEGDTAVATPYTAAVLEYRVSIHDSEDAKFNDINMANGNGYTVFDAQHP 241
Query: 313 YKANVAVKRELHTPESDRSCIHLEFDIAGSGLTYETGDHVGVLCDNLSETVDEALRLLDM 372
YKANVAVKRELHTPESDRSCIHLEFDIAGSGLTYETGDHVGVLCDNLSETVDEALRLLDM
Sbjct: 242 YKANVAVKRELHTPESDRSCIHLEFDIAGSGLTYETGDHVGVLCDNLSETVDEALRLLDM 301
Query: 373 SPDTYFSLHAEKEDGTPISSSLPPPFPPCNLRTALTRYACLLSSPKKSALVALAAHASDP 432
SPDTYFSLHAEKEDGTPISSSLPPPFPPCNLRTALTRYACLLSSPKKSALVALAAHASDP
Sbjct: 302 SPDTYFSLHAEKEDGTPISSSLPPPFPPCNLRTALTRYACLLSSPKKSALVALAAHASDP 361
Query: 433 TEAERLKHLASPAGKDEYSKWVVESQRSLLEVMAEFPSAKPPLGVFFAGVAPRLQPRFYS 492
TEAERLKHLASPAGKDEYSKWVVESQRSLLEVMAEFPSAKPPLGVFFAGVAPRLQPRFYS
Sbjct: 362 TEAERLKHLASPAGKDEYSKWVVESQRSLLEVMAEFPSAKPPLGVFFAGVAPRLQPRFYS 421
Query: 493 ISSSPKIAETRIHVTCALVYEKMPTGRIHKGVCSTWMKNAVPYEKSENCSSAPIFVRQSN 552
ISSSPKIAETRIHVTCALVYEKMPTGRIHKGVCSTWMKNAVPYEKSENCSSAPIFVRQSN
Sbjct: 422 ISSSPKIAETRIHVTCALVYEKMPTGRIHKGVCSTWMKNAVPYEKSENCSSAPIFVRQSN 481
Query: 553 FKLPSDSKVPIIMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEE 612
FKLPSDSKVPIIMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEE
Sbjct: 482 FKLPSDSKVPIIMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEE 541
Query: 613 ELQRFVESGALAELSVAFSREGPTKEYVQHKMMDKASDIWNMISQGAYLYVCGDAKGMAR 672
ELQRFVESGALAELSVAFSREGPTKEYVQHKMMDKASDIWNMISQGAYLYVCGDAKGMAR
Sbjct: 542 ELQRFVESGALAELSVAFSREGPTKEYVQHKMMDKASDIWNMISQGAYLYVCGDAKGMAR 601
Query: 673 DVHRSLHTIAQEQGSMDSTKAEGFVKNLQTSGRYLRDVW 711
DVHRSLHTIAQEQGSMDSTKAEGFVKNLQTSGRYLRDVW
Sbjct: 602 DVHRSLHTIAQEQGSMDSTKAEGFVKNLQTSGRYLRDVW 640
>6J79-A nrPDB
Length = 871
Score = 454 bits (1167), Expect = e-128, Method: Compositional matrix adjust.
Identities = 250/625 (40%), Positives = 369/625 (59%), Gaps = 31/625 (4%)
Query: 96 EEIDDGRKKVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYEEKL 155
E++ + + +F+G+QTGTAE FA L ++A RY R D ++Y D ++
Sbjct: 268 EKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAH-RY-GMRGMSADPEEYDLADLSSLPEI 325
Query: 156 KKEDVAFFFLATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKV 215
K + F +ATYG+G+PTDNA FY W E + L +K+ VFGLGN+ YEHFN +
Sbjct: 326 DK-SLVVFCMATYGEGDPTDNAQDFYDWLQETDVD---LTGVKFAVFGLGNKTYEHFNAM 381
Query: 216 AKVVDDILVEQGAQRLVQVGLGDDDQCIEDDFTAWREALWPELDTILREEGDTAVATPYT 275
K VD L + GAQR+ ++GLGDDD +E+DF WRE WP + E
Sbjct: 382 GKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEA--------- 432
Query: 276 AAVLEYRVSIHDSED-AKFNDINMANGNGYT----VFDAQHPYKANVAVKRELHTPESDR 330
+++ +Y + +H+ D AK M Y FDA++P+ A V R+L+ ++R
Sbjct: 433 SSIRQYELVVHEDMDVAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVTANRKLNQG-TER 491
Query: 331 SCIHLEFDIAGSGLTYETGDHVGVLCDNLSETVDEALRLLDMSPDTYFSLHAEKEDGTPI 390
+HLE DI+ S + YE+GDHV V N S V++ +L D SL+ E+
Sbjct: 492 HLMHLELDISDSKIRYESGDHVAVYPANDSALVNQIGEILGADLDVIMSLNNLDEE---- 547
Query: 391 SSSLPPPFP-PCNLRTALTRYACLLSSPKKSALVALAAHASDPTEAERLKHLASPAG--K 447
S+ PFP P RTALT Y + + P+ + L LA +AS+P+E E L +AS +G K
Sbjct: 548 -SNKKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGK 606
Query: 448 DEYSKWVVESQRSLLEVMAEFPSAKPPLGVFFAGVAPRLQPRFYSISSSPKIAETRIHVT 507
+ Y WVVE++R +L ++ ++PS +PP+ + PRLQ R+YSI+SS K+ +H+
Sbjct: 607 ELYLSWVVEARRHILAILQDYPSLRPPID-HLCELLPRLQARYYSIASSSKVHPNSVHIC 665
Query: 508 CALVYEKMPTGRIHKGVCSTWMKNAVPYEKSENCSSAPIFVRQSNFKLPSDSKVPIIMIG 567
V + +GR++KGV ++W++ P ++ + P+FVR+S F+LP S P+IM+G
Sbjct: 666 AVAVEYEAKSGRVNKGVATSWLRAKEPAGENGGRALVPMFVRKSQFRLPFKSTTPVIMVG 725
Query: 568 PGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEEELQRFVESGALAELS 627
PGTG+APF GF+QER L E G E+G ++L++GCR D++Y EEL RF + GAL +L+
Sbjct: 726 PGTGIAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLN 785
Query: 628 VAFSREGPTKEYVQHKMMDKASDIWNMISQ-GAYLYVCGDAKGMARDVHRSLHTIAQEQG 686
VAFSRE K YVQH + +W +I + GA++YVCGDA+ MA+DV + + I E G
Sbjct: 786 VAFSREQAHKVYVQHLLKRDREHLWKLIHEGGAHIYVCGDARNMAKDVQNTFYDIVAEFG 845
Query: 687 SMDSTKAEGFVKNLQTSGRYLRDVW 711
M+ T+A +VK L T GRY DVW
Sbjct: 846 PMEHTQAVDYVKKLMTKGRYSLDVW 870
>3ES9-A nrPDB
Length = 618
Score = 453 bits (1165), Expect = e-127, Method: Compositional matrix adjust.
Identities = 251/625 (40%), Positives = 369/625 (59%), Gaps = 31/625 (4%)
Query: 96 EEIDDGRKKVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYEEKL 155
E++ + + +F+G+QTGTAE FA L ++A RY R D ++Y D ++
Sbjct: 15 EKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAH-RY-GMRGMSADPEEYDLADLSSLPEI 72
Query: 156 KKEDVAFFFLATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKV 215
K V F +ATYG+G+PTDNA FY W E + L +K+ VFGLGN+ YEHFN +
Sbjct: 73 DKSLVVFC-MATYGEGDPTDNAQDFYDWLQETDVD---LTGVKFAVFGLGNKTYEHFNAM 128
Query: 216 AKVVDDILVEQGAQRLVQVGLGDDDQCIEDDFTAWREALWPELDTILREEGDTAVATPYT 275
K VD L + GAQR+ ++GLGDDD +E+DF WRE WP + E
Sbjct: 129 GKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEA--------- 179
Query: 276 AAVLEYRVSIHDSED-AKFNDINMANGNGYTV----FDAQHPYKANVAVKRELHTPESDR 330
+++ +Y + +H+ D AK M Y FDA++P+ A V R+L+ ++R
Sbjct: 180 SSIRQYELVVHEDMDVAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVTANRKLNQG-TER 238
Query: 331 SCIHLEFDIAGSGLTYETGDHVGVLCDNLSETVDEALRLLDMSPDTYFSLHAEKEDGTPI 390
+HLE DI+ S + YE+GDHV V N S V++ +L D SL+ E+
Sbjct: 239 HLMHLELDISDSKIRYESGDHVAVYPANDSALVNQIGEILGADLDVIMSLNNLDEE---- 294
Query: 391 SSSLPPPFP-PCNLRTALTRYACLLSSPKKSALVALAAHASDPTEAERLKHLASPAG--K 447
S+ PFP P RTALT Y + + P+ + L LA +AS+P+E E L +AS +G K
Sbjct: 295 -SNKKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGK 353
Query: 448 DEYSKWVVESQRSLLEVMAEFPSAKPPLGVFFAGVAPRLQPRFYSISSSPKIAETRIHVT 507
+ Y WVVE++R +L ++ ++PS +PP+ + PRLQ R+YSI+SS K+ +H+
Sbjct: 354 ELYLSWVVEARRHILAILQDYPSLRPPID-HLCELLPRLQARYYSIASSSKVHPNSVHIC 412
Query: 508 CALVYEKMPTGRIHKGVCSTWMKNAVPYEKSENCSSAPIFVRQSNFKLPSDSKVPIIMIG 567
V + +GR++KGV ++W++ P ++ + P+FVR+S F+LP S P+IM+G
Sbjct: 413 AVAVEYEAKSGRVNKGVATSWLRAKEPAGENGGRALVPMFVRKSQFRLPFKSTTPVIMVG 472
Query: 568 PGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEEELQRFVESGALAELS 627
PGTG+APF GF+QER L E G E+G ++L++GCR D++Y EEL RF + GAL +L+
Sbjct: 473 PGTGIAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLN 532
Query: 628 VAFSREGPTKEYVQHKMMDKASDIWNMISQ-GAYLYVCGDAKGMARDVHRSLHTIAQEQG 686
VAFSRE K YVQH + +W +I + GA++YVCGDA+ MA+DV + + I E G
Sbjct: 533 VAFSREQAHKVYVQHLLKRDREHLWKLIHEGGAHIYVCGDARNMAKDVQNTFYDIVAEFG 592
Query: 687 SMDSTKAEGFVKNLQTSGRYLRDVW 711
M+ T+A +VK L T GRY DVW
Sbjct: 593 PMEHTQAVDYVKKLMTKGRYSLDVW 617
>3QFR-A nrPDB
Length = 618
Score = 450 bits (1157), Expect = e-126, Method: Compositional matrix adjust.
Identities = 250/630 (39%), Positives = 371/630 (58%), Gaps = 38/630 (6%)
Query: 96 EEIDDGRKKVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYE--- 152
E++ + + +F+G+QTGTAE FA L ++A RY + +AD +EY+
Sbjct: 12 EKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAH-RY--------GMRGMSADPEEYDLAD 62
Query: 153 -EKLKKEDVAF--FFLATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQY 209
L + D A F +ATYG+G+PTDNA FY W E + L +K+ VFGLGN+ Y
Sbjct: 63 LSSLPEIDNALVVFCMATYGEGDPTDNAQDFYDWLQETDVD---LSGVKFAVFGLGNKTY 119
Query: 210 EHFNKVAKVVDDILVEQGAQRLVQVGLGDDDQCIEDDFTAWREALWPELDTILREEGDTA 269
EHFN + K VD L + GAQR+ ++GLGDDD +E+DF WRE WP + E
Sbjct: 120 EHFNAMGKYVDKRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEHFGVE---- 175
Query: 270 VATPYTAAVLEYRVSIH-DSEDAKFNDINMANGNGYTV----FDAQHPYKANVAVKRELH 324
AT +++ +Y + +H D + AK M Y FDA++P+ A V R+L+
Sbjct: 176 -ATGEESSIRQYELVVHTDIDAAKVYMGEMGRLKSYENQKPPFDAKNPFLAAVTTNRKLN 234
Query: 325 TPESDRSCIHLEFDIAGSGLTYETGDHVGVLCDNLSETVDEALRLLDMSPDTYFSLHAEK 384
++R +HLE DI+ S + YE+GDHV V N S V++ ++L D SL+
Sbjct: 235 QG-TERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQLGKILGADLDVVMSLNNLD 293
Query: 385 EDGTPISSSLPPPFP-PCNLRTALTRYACLLSSPKKSALVALAAHASDPTEAERLKHLAS 443
E+ S+ PFP P + RTALT Y + + P+ + L LA +AS+P+E E L+ +AS
Sbjct: 294 EE-----SNKKHPFPCPTSYRTALTYYLDITNPPRTNVLYELAQYASEPSEQELLRKMAS 348
Query: 444 PAG--KDEYSKWVVESQRSLLEVMAEFPSAKPPLGVFFAGVAPRLQPRFYSISSSPKIAE 501
+G K+ Y WVVE++R +L ++ + PS +PP+ + PRLQ +YSI+SS K+
Sbjct: 349 SSGEGKELYLSWVVEARRHILAILQDCPSLRPPID-HLCELLPRLQAHYYSIASSSKVHP 407
Query: 502 TRIHVTCALVYEKMPTGRIHKGVCSTWMKNAVPYEKSENCSSAPIFVRQSNFKLPSDSKV 561
+H+ +V + GRI+KGV + W++ P ++ + P+FVR+S F+LP +
Sbjct: 408 NSVHICAVVVEYETKAGRINKGVATNWLRAKEPAGENGGRALVPMFVRKSQFRLPFKATT 467
Query: 562 PIIMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEEELQRFVESG 621
P+IM+GPGTG+APF GF+QER L + G E+G ++L++GCR D++Y EEL +F G
Sbjct: 468 PVIMVGPGTGVAPFIGFIQERAWLRQQGKEVGETLLYYGCRRSDEDYLYREELAQFHRDG 527
Query: 622 ALAELSVAFSREGPTKEYVQHKMMDKASDIWNMISQGAYLYVCGDAKGMARDVHRSLHTI 681
AL +L+VAFSRE K YVQH + +W +I GA++YVCGDA+ MARDV + + I
Sbjct: 528 ALTQLNVAFSREQSHKVYVQHLLKQDREHLWKLIEGGAHIYVCGDARNMARDVQNTFYDI 587
Query: 682 AQEQGSMDSTKAEGFVKNLQTSGRYLRDVW 711
E G+M+ +A ++K L T GRY DVW
Sbjct: 588 VAELGAMEHAQAVDYIKKLMTKGRYSLDVW 617
>3FJO-A nrPDB
Length = 637
Score = 405 bits (1041), Expect = e-113, Method: Compositional matrix adjust.
Identities = 235/625 (37%), Positives = 355/625 (56%), Gaps = 33/625 (5%)
Query: 98 IDDGRKKVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYE-EKLK 156
+ + K + + +QTGTAE +AK +E A++ +L+ AD + Y+ E L
Sbjct: 34 VTENNKNYLVLYASQTGTAEDYAKKFSKELVAKF--------NLNVMCADVENYDFESLN 85
Query: 157 KEDVAF-FFLATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKV 215
V F++TYG+G+ D A F + N L NL+Y +FGLGN YE FN
Sbjct: 86 DVPVIVSIFISTYGEGDFPDGAVNFEDFIC--NAEAGALSNLRYNMFGLGNSTYEFFNGA 143
Query: 216 AKVVDDILVEQGAQRLVQVGLGDDDQCIED-DFTAWREALWPELDTILREEGDTAVATPY 274
AK + L GA RL ++G DD D D+ AW++++ L L E AT
Sbjct: 144 AKKAEKHLSAAGAIRLGKLGEADDGAGTTDEDYMAWKDSILEVLKDELGVE-----ATGE 198
Query: 275 TAAVLEYRVSIH-DSEDAKFNDINMANGNGYTV----FDAQHPYKANVAVKRELHTPESD 329
+++ +Y + +H D + AK M Y FDA++P+ A V R+L+ ++
Sbjct: 199 ESSIRQYELVVHTDIDAAKVYMGEMGRLKSYENQKPPFDAKNPFLAAVTTNRKLNQG-TE 257
Query: 330 RSCIHLEFDIAGSGLTYETGDHVGVLCDNLSETVDEALRLLDMSPDTYFSLHAEKEDGTP 389
R +HLE DI+ S + YE+GDHV V N S V++ ++L D SL+ E+
Sbjct: 258 RHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQLGKILGADLDVVMSLNNLDEE--- 314
Query: 390 ISSSLPPPFP-PCNLRTALTRYACLLSSPKKSALVALAAHASDPTEAERLKHLASPAG-- 446
S+ PFP P + RTALT Y + + P+ + L LA +AS+P+E E L+ +AS +G
Sbjct: 315 --SNKKHPFPCPTSYRTALTYYLDITNPPRTNVLYELAQYASEPSEQELLRKMASSSGEG 372
Query: 447 KDEYSKWVVESQRSLLEVMAEFPSAKPPLGVFFAGVAPRLQPRFYSISSSPKIAETRIHV 506
K+ Y WVVE++R +L ++ + PS +PP+ + PRLQ R+YSI+SS K+ +H+
Sbjct: 373 KELYLSWVVEARRHILAILQDCPSLRPPID-HLCELLPRLQARYYSIASSSKVHPNSVHI 431
Query: 507 TCALVYEKMPTGRIHKGVCSTWMKNAVPYEKSENCSSAPIFVRQSNFKLPSDSKVPIIMI 566
+V + GRI+KGV + W++ P ++ + P+FVR+S F+LP + P+IM+
Sbjct: 432 CAVVVEYETKAGRINKGVATNWLRAKEPAGENGGRALVPMFVRKSQFRLPFKATTPVIMV 491
Query: 567 GPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEEELQRFVESGALAEL 626
GPGTG+APF GF+QER L + G E+G ++L++GCR D++Y EEL +F GAL +L
Sbjct: 492 GPGTGVAPFIGFIQERAWLRQQGKEVGETLLYYGCRRSDEDYLYREELAQFHRDGALTQL 551
Query: 627 SVAFSREGPTKEYVQHKMMDKASDIWNMISQGAYLYVCGDAKGMARDVHRSLHTIAQEQG 686
+VAFSRE K YVQH + +W +I GA++YVCGDA+ MARDV + + I E G
Sbjct: 552 NVAFSREQSHKVYVQHLLKQDREHLWKLIEGGAHIYVCGDARNMARDVQNTFYDIVAELG 611
Query: 687 SMDSTKAEGFVKNLQTSGRYLRDVW 711
+M+ +A ++K L T GRY DVW
Sbjct: 612 AMEHAQAVDYIKKLMTKGRYSLDVW 636
>2BN4-A nrPDB
Length = 682
Score = 294 bits (752), Expect = 1e-79, Method: Compositional matrix adjust.
Identities = 213/665 (32%), Positives = 328/665 (49%), Gaps = 78/665 (11%)
Query: 98 IDDGRKKVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYE-EKLK 156
+ + K + + +QTGTAE +AK +E A++ +L+ AD + Y+ E L
Sbjct: 45 VTENNKNYLVLYASQTGTAEDYAKKFSKELVAKF--------NLNVMCADVENYDFESLN 96
Query: 157 KEDVAF-FFLATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKV 215
V F++TYG+G+ D A F + N L NL+Y +FGLGN YE FN
Sbjct: 97 DVPVIVSIFISTYGEGDFPDGAVNFEDFIC--NAEAGALSNLRYNMFGLGNSTYEFFNGA 154
Query: 216 AKVVDDILVEQGAQRLVQVGLGDDDQCIED-DFTAWREALWPEL-DTILREEGDTAVATP 273
AK + L GA RL ++G DD D D+ AW++++ L D + +E + +
Sbjct: 155 AKKAEKHLSAAGAIRLGKLGEADDGAGTTDEDYMAWKDSILEVLKDELHLDEQEAKFTSQ 214
Query: 274 YTAAVLEYRV--------SIHDSEDAKFNDINMANGNGYTVFDAQHPYKANVAVKRELHT 325
+ VL S H + N A+G FD PY A + REL +
Sbjct: 215 FQYTVLNEITDSMSLGEPSAHYLPSHQLN--RNADGIQLGPFDLSQPYIAPIVKSRELFS 272
Query: 326 PESDRSCIHLEFDIAGSGLTYETGDHVGVLCDNLSETVDEALRLLDMSPDTYFSLHAEKE 385
+DR+CIH EFD++GS + Y TGDH+ V N E V++ L + ++ P+T F L
Sbjct: 273 -SNDRNCIHSEFDLSGSNIKYSTGDHLAVWPSNPLEKVEQFLSIFNLDPETIFDLK---- 327
Query: 386 DGTPISSSLPPPFP-PCNLRTALTRYACLLSSPKKSALVALAAHASDPTEAERLKHLASP 444
P+ ++ PFP P + A+ Y + + +L A + E+L L+
Sbjct: 328 ---PLDPTVKVPFPTPTTIGAAIKHYLEITGPVSRQLFSSLIQFAPNADVKEKLTLLSK- 383
Query: 445 AGKDEYSKWVVESQRSLLEVMAEFPSAKP----PLGVFFAGVAPRLQPRFYSISSSPKIA 500
KD+++ + ++ + + P+ F P++ PR+YSISSS
Sbjct: 384 -DKDQFAVEITSKYFNIADALKYLSDGAKWDTVPMQ-FLVESVPQMTPRYYSISSSSLSE 441
Query: 501 ETRIHVTCALVYEKMPTGRIHK-----GVCSTWMKNAVPYEKSENCSSA----------- 544
+ +HVT + E P + GV + ++N + + N +
Sbjct: 442 KQTVHVTS--IVENFPNPELPDAPPVVGVTTNLLRNIQLAQNNVNIAETNLPVHYDLNGP 499
Query: 545 ---------PIFVRQSNFKLPSDSKVPIIMIGPGTGLAPFRGFLQERLALVES------G 589
P+ VR+SNF+LPS+ P+IMIGPGTG+APFRGF++ER+A +ES
Sbjct: 500 RKLFANYKLPVHVRRSNFRLPSNPSTPVIMIGPGTGVAPFRGFIRERVAFLESQKKGGNN 559
Query: 590 VELGPSVLFFGCRNRRMDFIYEEELQRFVES--GALAELSVAFSREGPTKE-YVQHKMMD 646
V LG +LF+G RN DF+Y++E + + G+ E+ VA SR TK+ YVQ K+ D
Sbjct: 560 VSLGKHILFYGSRNTD-DFLYQDEWPEYAKKLDGSF-EMVVAHSRLPNTKKVYVQDKLKD 617
Query: 647 KASDIWNMISQGAYLYVCGDAKGMARDVHRSLHTIAQEQGSMDSTKAEGFVKNLQTSGRY 706
++ MI+ GA++YVCGDAKGMA+ V +L I S+ + +A +K L+TSGRY
Sbjct: 618 YEDQVFEMINNGAFIYVCGDAKGMAKGVSTALVGILSRGKSITTDEATELIKMLKTSGRY 677
Query: 707 LRDVW 711
DVW
Sbjct: 678 QEDVW 682
>1TLL-A nrPDB
Length = 688
Score = 248 bits (634), Expect = 5e-66, Method: Compositional matrix adjust.
Identities = 191/668 (28%), Positives = 306/668 (45%), Gaps = 82/668 (12%)
Query: 102 RKKVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYE-EKLKKEDV 160
R K TI + T+TG ++ +AK L E K + D A +EY+ L+ E +
Sbjct: 11 RVKATILYATETGKSQAYAKTLCEIFKHAF----------DAKAMSMEEYDIVHLEHEAL 60
Query: 161 AFFFLATYGDGEPTDNAARFYKWFTE-------GNDRGEW-------------------- 193
+T+G+G+P +N +F E +R +
Sbjct: 61 VLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVQEERKSYKVRFNSVSSYSDSRKSSGDG 120
Query: 194 ------------LKNLKYGVFGLGNRQYEHFNKVAKVVDDILVEQGAQRLVQVGLGDDDQ 241
L N+++ VFGLG+R Y HF VD +L E G +R++++ GD+
Sbjct: 121 PDLRDNFESTGPLANVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKMREGDELC 180
Query: 242 CIEDDFTAWREALWPELDTILREEGDTAVATPYTAAVLEYRVSIHDSEDAKFNDINMANG 301
E+ F W + ++ + D + P + + R + KF +A
Sbjct: 181 GQEEAFRTWAKKVFKAACDVFCVGDDVNIEKPNNSLISNDR----SWKRNKFRLTYVAEA 236
Query: 302 ----NGYTVFDAQHPYKANVAVKRELHTPESDRSCIHLEFDIAGSG-LTYETGDHVGVLC 356
G + + A + ++ L +P+S RS I + G+ L Y+ GDH+GV
Sbjct: 237 PDLTQGLSNVHKKRVSAARLLSRQNLQSPKSSRSTIFVRLHTNGNQELQYQPGDHLGVFP 296
Query: 357 DNLSETVDEAL-RLLDMSPDTY---FSLHAEKEDGTPISSSLPPP--FPPCNLRTALTRY 410
N + V+ + RL D P + + E+ + S+ PPC + A Y
Sbjct: 297 GNHEDLVNALIERLEDAPPANHVVKVEMLEERNTALGVISNWKDESRLPPCTIFQAFKYY 356
Query: 411 ACLLSSPKKSALVALAAHASDPTEAERLKHLASPAGKDEYSKWVVESQRSLLEVMAEFPS 470
+ + P L A+ A++ E +RL L G EY +W +++EV+ EFPS
Sbjct: 357 LDITTPPTPLQLQQFASLATNEKEKQRL--LVLSKGLQEYEEWKWGKNPTMVEVLEEFPS 414
Query: 471 AKPPLGVFFAGVAPRLQPRFYSISSSPKIAETRIHVTCALV--YEKMPTGRIHKGVCSTW 528
+ P LQPR+YSISSSP + +H+T A+V + + G +H GVCS+W
Sbjct: 415 IQMP-ATLLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYHTRDGEGPVHHGVCSSW 473
Query: 529 MKNAVPYEKSENCSSAPIFVRQS-NFKLPSDSKVPIIMIGPGTGLAPFRGFLQER-LALV 586
+ + + P FVR + +F LP + +VP I++GPGTG+APFR F Q+R +
Sbjct: 474 LN------RIQADDVVPCFVRGAPSFHLPRNPQVPCILVGPGTGIAPFRSFWQQRQFDIQ 527
Query: 587 ESGVELGPSVLFFGCRNRRMDFIYEEELQRFVESGALAELSVAFSRE-GPTKEYVQHKMM 645
G+ P VL FGCR ++D IY EE + G EL A+SRE K+YVQ +
Sbjct: 528 HKGMNPCPMVLVFGCRQSKIDHIYREETLQAKNKGVFRELYTAYSREPDRPKKYVQDVLQ 587
Query: 646 DK-ASDIWNMIS-QGAYLYVCGDAKGMARDVHRSLHTIAQEQGSMDSTKAEGFVKNLQTS 703
++ A ++ + QG ++YVCGD MA DV +++ I +QG + A F+ L+
Sbjct: 588 EQLAESVYRALKEQGGHIYVCGDVT-MAADVLKAIQRIMTQQGKLSEEDAGVFISRLRDD 646
Query: 704 GRYLRDVW 711
RY D++
Sbjct: 647 NRYHEDIF 654
>6EFV-A nrPDB
Length = 569
Score = 231 bits (589), Expect = 8e-61, Method: Compositional matrix adjust.
Identities = 178/612 (29%), Positives = 286/612 (46%), Gaps = 85/612 (13%)
Query: 104 KVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYEEKLKKEDVAFF 163
++TI +QTG A A+AL ++ A K K+V+ DY +++ E +
Sbjct: 39 EITIISASQTGNARRVAEALRDDLLA--AKLNVKLVNAGDYKF------KQIASEKLLIV 90
Query: 164 FLATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKVAKVVDDIL 223
+T G+GEP + A +K+ + + L+N + VF LG+ YE F + K D L
Sbjct: 91 VTSTQGEGEPPEEAVALHKFLF--SKKAPKLENTAFAVFSLGDSSYEFFCQSGKDFDSKL 148
Query: 224 VEQGAQRLVQVGLGDDDQCIEDDFTAWREALWPELDTILREEGDTAVATPYTAAVLEYRV 283
E G +RL+ R + D Y AA E+R
Sbjct: 149 AELGGERLLD-----------------------------RVDADV----EYQAAASEWRA 175
Query: 284 SIHDSEDAKFNDINMANGNGYTV--FDAQHPYKANVAVKRELHTPESDRSCIHLEFDIAG 341
+ D+ ++ + N + P A+++V +++ S++ H+E D+
Sbjct: 176 RVVDALKSRAPVVATGAVNEIHTSPYSKDAPLVASLSVNQKITGRNSEKDVRHIEIDLGD 235
Query: 342 SGLTYETGDHVGVLCDNLSETVDEALRLLDMSPDTYFSLHAEKEDGTPISSSLPPPFP-P 400
SGL Y+ GD +GV N V E + LL + D ++ + P++ +L F
Sbjct: 236 SGLRYQPGDALGVWYQNDPALVKELVELLWLKGDEPVTVEGKT---LPLNEALQWHFELT 292
Query: 401 CNLRTALTRYACLLSSPKKSALVALAAHASDPTEAERLKHLASPAGKDEYSKWVVESQRS 460
N + YA L S LV A +L+H A+ +V+
Sbjct: 293 VNTANIVENYATLTRSETLLPLVGDKA---------KLQHYAATTP-------IVD---- 332
Query: 461 LLEVMAEFPSAKPPLGVFFAGVAPRLQPRFYSISSSPKIAETRIHVTCALVYEKMPTGRI 520
M F A+ + P L PR YSI+SS E +HVT +V + GR
Sbjct: 333 ----MVRFSPAQLDAEALINLLRP-LTPRLYSIASSQAEVENEVHVTVGVVRYDV-EGRA 386
Query: 521 HKGVCSTWMKNAVPYEKSENCSSAPIFVRQS-NFKLPSDSKVPIIMIGPGTGLAPFRGFL 579
G S+++ + V E +F+ + NF+LP++ + P+IMIGPGTG+APFR F+
Sbjct: 387 RAGGASSFLADRV-----EEEGEVRVFIEHNDNFRLPANPETPVIMIGPGTGIAPFRAFM 441
Query: 580 QERLALVESGVELGPSVLFFGCRNRRMDFIYEEELQRFVESGALAELSVAFSREGPTKEY 639
Q+R A G + LFFG + DF+Y+ E QR+V+ G L + +A+SR+ K Y
Sbjct: 442 QQRAA----DEAPGKNWLFFGNPHFTEDFLYQVEWQRYVKEGVLTRIDLAWSRDQKEKVY 497
Query: 640 VQHKMMDKASDIWNMISQGAYLYVCGDAKGMARDVHRSLHTIAQEQGSMDSTKAEGFVKN 699
VQ K+ ++ +++W I+ GA++YVCGDA MA+DV ++L + E G MD+ A+ F+
Sbjct: 498 VQDKLREQGAELWRWINDGAHIYVCGDANRMAKDVEQALLEVIAEFGGMDTEAADEFLSE 557
Query: 700 LQTSGRYLRDVW 711
L+ RY RDV+
Sbjct: 558 LRVERRYQRDVY 569
>1B1C-A nrPDB
Length = 181
Score = 127 bits (320), Expect = 1e-29, Method: Compositional matrix adjust.
Identities = 71/160 (44%), Positives = 97/160 (60%), Gaps = 18/160 (11%)
Query: 103 KKVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYE----EKLKKE 158
+ + +F+G+QTGTAE FA L ++A RY + +AD +EY+ L +
Sbjct: 18 RNIIVFYGSQTGTAEEFANRLSKDAH-RY--------GMRGMSADPEEYDLADLSSLPEI 68
Query: 159 DVAF--FFLATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKVA 216
D A F +ATYG+G+PTDNA FY W E + L +K+ VFGLGN+ YEHFN +
Sbjct: 69 DNALVVFCMATYGEGDPTDNAQDFYDWLQETDVD---LSGVKFAVFGLGNKTYEHFNAMG 125
Query: 217 KVVDDILVEQGAQRLVQVGLGDDDQCIEDDFTAWREALWP 256
K VD L + GAQR+ ++GLGDDD +E+DF WRE WP
Sbjct: 126 KYVDKRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWP 165
>1BVY-F nrPDB
Length = 191
Score = 69.7 bits (169), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 42/153 (27%), Positives = 76/153 (49%), Gaps = 13/153 (8%)
Query: 107 IFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYEEKLKKEDVAFFFLA 166
+ +G+ GTAEG A+ L + A ++ ++ LD +A + L +E A
Sbjct: 26 VLYGSNMGTAEGTARDLADIAMSK--GFAPQVATLDSHAGN-------LPREGAVLIVTA 76
Query: 167 TYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQY-EHFNKVAKVVDDILVE 225
+Y +G P DNA +F W + + + +K ++Y VFG G++ + + KV +D+ L
Sbjct: 77 SY-NGHPPDNAKQFVDWLDQAS--ADEVKGVRYSVFGCGDKNWATTYQKVPAFIDETLAA 133
Query: 226 QGAQRLVQVGLGDDDQCIEDDFTAWREALWPEL 258
+GA+ + G D E + WRE +W ++
Sbjct: 134 KGAENIADRGEADASDDFEGTYEEWREHMWSDV 166
>4H2D-A nrPDB
Length = 165
Score = 66.6 bits (161), Expect = 4e-11, Method: Composition-based stats.
Identities = 51/154 (33%), Positives = 74/154 (48%), Gaps = 10/154 (6%)
Query: 104 KVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYEEKLKKEDVAFF 163
++ + FG+QTGTA+ ++ LG EA+ R R + LD Y + L E + F
Sbjct: 9 QLLVLFGSQTGTAQDVSERLGREARRRRLGCRVQA--LDSYPVVN------LINEPLVIF 60
Query: 164 FLATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKVAKVVDDIL 223
AT G G+P DN F+++ N L + + V GLG+ Y FN VAK + L
Sbjct: 61 VCATTGQGDPPDNMKNFWRFIFRKNLPSTALCQMDFAVLGLGDSSYAKFNFVAKKLHRRL 120
Query: 224 VEQGAQRLVQVGLGDDDQCIEDDFTA--WREALW 255
++ G L+ V LGDD + D W LW
Sbjct: 121 LQLGGSALLPVCLGDDQHELGPDAAVDPWLRDLW 154
>2B5O-A nrPDB
Length = 402
Score = 65.9 bits (159), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 57/209 (27%), Positives = 100/209 (47%), Gaps = 17/209 (8%)
Query: 489 RFYSISSSPK--IAETRIHVTCA--LVYEKMPTGRIHKGVCSTWMKNAVPYEKSENCSSA 544
R YSI+S+ + + + C L Y+ +G GVCST++ N +P + +
Sbjct: 179 RLYSIASTRHGDMEDNKTVSLCVRQLEYQDPESGETVYGVCSTYLCN-LPVGTDDVKITG 237
Query: 545 PIFVRQSNFKLPSDSKVPIIMIGPGTGLAPFRGFLQERLALVESGVEL-GPSVLFFGCRN 603
P+ LP D ++M+ GTG+APFR FL + G + L FG
Sbjct: 238 PV---GKEMLLPDDEDATVVMLATGTGIAPFRAFLWRMFKEQHEDYKFKGKAWLIFGV-P 293
Query: 604 RRMDFIYEEELQRF-VESGALAELSVAFSREGPT----KEYVQHKMMDKASDIWNMISQ- 657
+ +Y+++ ++ E+ L+ A SRE T K YVQ ++ + A +++ MI +
Sbjct: 294 YTANILYKDDFEKMAAENPDNFRLTYAISREQKTADGGKVYVQSRVSEYADELFEMIQKP 353
Query: 658 GAYLYVCGDAKGMARDVHRSLHTIAQEQG 686
++Y+CG KGM + + A+++G
Sbjct: 354 NTHVYMCG-LKGMQPPIDETFTAEAEKRG 381
>3HR4-A nrPDB
Length = 219
Score = 63.2 bits (152), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 46/152 (30%), Positives = 69/152 (45%), Gaps = 18/152 (11%)
Query: 102 RKKVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYEEKLKKEDVA 161
R +VTI F T+TG +E A LG + K+V +D Y L++E +
Sbjct: 40 RVRVTILFATETGKSEALAWDLGALFSCAFNP---KVVCMDKYRLSC------LEEERLL 90
Query: 162 FFFLATYGDGEPTDNAARFYK---WFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKVAKV 218
+T+G+G+ N + K E N++ +Y VFGLG+ Y F A
Sbjct: 91 LVVTSTFGNGDCPGNGEKLKKSLFMLKELNNK------FRYAVFGLGSSMYPRFCAFAHD 144
Query: 219 VDDILVEQGAQRLVQVGLGDDDQCIEDDFTAW 250
+D L GA +L +G GD+ ED F +W
Sbjct: 145 IDQKLSHLGASQLTPMGEGDELSGQEDAFRSW 176
>1YKG-A nrPDB
Length = 167
Score = 57.4 bits (137), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 39/128 (30%), Positives = 63/128 (49%), Gaps = 10/128 (7%)
Query: 105 VTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYEEKLKKEDVAFFF 164
+TI +QTG A A+AL ++ A K K+V+ DY +++ E +
Sbjct: 12 ITIISASQTGNARRVAEALRDDLLA--AKLNVKLVNAGDYKF------KQIASEKLLIVV 63
Query: 165 LATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKVAKVVDDILV 224
+T G+GEP + A +K+ + + L+N + VF LG+ YE F + K D L
Sbjct: 64 TSTQGEGEPPEEAVALHKFLF--SKKAPKLENTAFAVFSLGDTSYEFFCQSGKDFDSKLA 121
Query: 225 EQGAQRLV 232
E G +RL+
Sbjct: 122 ELGGERLL 129
>2M6S-A nrPDB
Length = 149
Score = 43.9 bits (102), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 39/140 (27%), Positives = 63/140 (45%), Gaps = 21/140 (15%)
Query: 104 KVTIFFGTQTGTAEGFAKALGEEAKA-----RYEKTRFKIVDLDDYAADDDEYEEKLKKE 158
++ IF GT G + + EEA+A ++ T F+ +L D+ D+Y
Sbjct: 3 EIGIFVGTMYGNS----LLVAEEAEAILTAQGHKATVFEDPELSDWLPYQDKY------- 51
Query: 159 DVAFFFLATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKVAKV 218
+T G G+ D+ ++ D + NL+YGV LG+ Y +F K
Sbjct: 52 --VLVVTSTTGQGDLPDSIVPLFQGI---KDSLGFQPNLRYGVIALGDSSYVNFCNGGKQ 106
Query: 219 VDDILVEQGAQRLVQVGLGD 238
D +L EQ AQR+ ++ L D
Sbjct: 107 FDALLQEQSAQRVGEMLLID 126
>5LJI-A nrPDB
Length = 148
Score = 42.4 bits (98), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 30/89 (33%), Positives = 43/89 (48%), Gaps = 8/89 (8%)
Query: 159 DVAFFFLATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKVAKV 218
D+A TYGDGE D FY+ + N G+ YGV G G+ Y+ F K
Sbjct: 50 DIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKI-----YGVVGSGDTFYDEFCKAVDD 104
Query: 219 VDDILVEQGAQR---LVQVGLGDDDQCIE 244
D + V GA++ V+V L +++ IE
Sbjct: 105 FDRVFVSTGAEKGSECVKVDLSAEEEDIE 133
>4HEQ-A nrPDB
Length = 146
Score = 39.3 bits (90), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 35/125 (28%), Positives = 56/125 (44%), Gaps = 10/125 (8%)
Query: 104 KVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYEEKLKKEDVAFF 163
K I +G+ TG EG A+A+ + + E +V++ D A + DV
Sbjct: 3 KALIVYGSTTGNTEGVAEAIAKTLNS--EGMETTVVNVADVTAPG-----LAEGYDVVLL 55
Query: 164 FLATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKVAKVVDDIL 223
+T+GD E + F + + + G LK+ K GVFG G+ Y +F V++
Sbjct: 56 GCSTWGDDE-IELQEDFVPLYEDLDRAG--LKDKKVGVFGCGDSSYTYFCGAVDVIEKKA 112
Query: 224 VEQGA 228
E GA
Sbjct: 113 EELGA 117
>5V57-A nrPDB
Length = 648
Score = 37.7 bits (86), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 41/158 (25%), Positives = 62/158 (39%), Gaps = 19/158 (12%)
Query: 98 IDDGRKKVTIFFGTQTGTAEGFAKALGEE-AKARYEKTRFKIVDLDDYAADDDEYEEKLK 156
I K I +G+ TG E A+ + E A A YE +D A E +
Sbjct: 372 IKSNHAKALIVYGSTTGNTEYTAETIARELADAGYE--------VDSRDAASVEAGGLFE 423
Query: 157 KEDVAFFFLATYGDG--EPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNK 214
D+ +T+GD E D+ + E +G K FG G+ +E+F
Sbjct: 424 GFDLVLLGCSTWGDDSIELQDDFIPLFDSLEETGAQGR-----KVACFGCGDSSWEYFCG 478
Query: 215 VAKVVDDILVEQGAQRLVQVGL--GDDDQCIEDDFTAW 250
+++ L GA+ +VQ GL D + DD W
Sbjct: 479 AVDAIEEKLKNLGAE-IVQDGLRIDGDPRAARDDIVGW 515
>2HNA-A nrPDB
Length = 147
Score = 37.4 bits (85), Expect = 0.025, Method: Compositional matrix adjust.
Identities = 31/126 (24%), Positives = 55/126 (43%), Gaps = 13/126 (10%)
Query: 105 VTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYEEKLKKEDVAFFF 164
+T+ G+ G AE A+ L E + E+ F L +D L +
Sbjct: 4 ITLISGSTLGGAEYVAEHLAE----KLEEAGFTTETLHGPLLED------LPASGIWLVI 53
Query: 165 LATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKVAKVVDDILV 224
+T+G G+ DN + FY+ E L +++G G+G+R+Y+ F ++ L
Sbjct: 54 SSTHGAGDIPDNLSPFYEALQEQKPD---LSAVRFGAIGIGSREYDTFCGAIDKLEAELK 110
Query: 225 EQGAQR 230
GA++
Sbjct: 111 NSGAKQ 116
>2FCR-A nrPDB
Length = 173
Score = 36.6 bits (83), Expect = 0.038, Method: Compositional matrix adjust.
Identities = 32/128 (25%), Positives = 56/128 (43%), Gaps = 11/128 (8%)
Query: 104 KVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYEEKLKKEDVAFF 163
K+ IFF T TG A +G+ A+ + +D+DD + LK D+ F
Sbjct: 1 KIGIFFSTSTGNTTEVADFIGKTLGAKADAP----IDVDDVTD-----PQALKDYDLLFL 51
Query: 164 FLATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQY--EHFNKVAKVVDD 221
T+ G T+ + + F +K+L +FGLG+ + ++F + + D
Sbjct: 52 GAPTWNTGADTERSGTSWDEFLYDKLPEVDMKDLPVAIFGLGDAEGYPDNFCDAIEEIHD 111
Query: 222 ILVEQGAQ 229
+QGA+
Sbjct: 112 CFAKQGAK 119
>4OXX-A nrPDB
Length = 162
Score = 36.6 bits (83), Expect = 0.040, Method: Compositional matrix adjust.
Identities = 38/129 (29%), Positives = 53/129 (41%), Gaps = 13/129 (10%)
Query: 107 IFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYEEKLKKEDVAFFFLA 166
I +GT+TG AE A + + + + D+ A D D+ F A
Sbjct: 5 ILYGTETGNAEACATTISQVLADTVDTKVHDLADMTPRAMLD-------SGADLIVFATA 57
Query: 167 TYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKVAKVVDDILVEQ 226
TYG+GE A F++ E L L++ VFGLG+ Y FN+ IL
Sbjct: 58 TYGEGEFAGGGAAFFETLRETKPD---LSGLRFAVFGLGDSYYTTFNQAGATAATILASL 114
Query: 227 GAQRLVQVG 235
G QVG
Sbjct: 115 GG---TQVG 120
>5XRA-A nrPDB
Length = 438
Score = 35.8 bits (81), Expect = 0.059, Method: Compositional matrix adjust.
Identities = 40/152 (26%), Positives = 61/152 (40%), Gaps = 19/152 (12%)
Query: 104 KVTIFFGTQTGTAEGFAKALGEE-AKARYEKTRFKIVDLDDYAADDDEYEEKLKKEDVAF 162
K I +G+ TG E A+ + E A A YE +D A E + D+
Sbjct: 210 KALIVYGSTTGNTEYTAETIARELADAGYE--------VDSRDAASVEAGGLFEGFDLVL 261
Query: 163 FFLATYGDG--EPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKVAKVVD 220
+T+GD E D+ + E +G K FG G+ +E+F ++
Sbjct: 262 LGCSTWGDDSIELQDDFIPLFDSLEETGAQGR-----KVACFGCGDSSWEYFCGAVDAIE 316
Query: 221 DILVEQGAQRLVQVGL--GDDDQCIEDDFTAW 250
+ L GA+ +VQ GL D + DD W
Sbjct: 317 EKLKNLGAE-IVQDGLRIDGDPRAARDDIVGW 347
>6GAQ-A nrPDB
Length = 154
Score = 35.8 bits (81), Expect = 0.066, Method: Compositional matrix adjust.
Identities = 26/70 (37%), Positives = 36/70 (51%), Gaps = 6/70 (8%)
Query: 167 TYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKVAKVVDDILVEQ 226
T+GDGE A F+ + L K VFG G+ YE F + + ++ LVE+
Sbjct: 65 TWGDGELPFEAEDFHDDLENID-----LAGKKVAVFGSGDTAYELFCEAVTIFEERLVER 119
Query: 227 GAQRLVQVGL 236
GA+ LVQ GL
Sbjct: 120 GAE-LVQEGL 128
>5ZKP-A nrPDB
Length = 466
Score = 35.0 bits (79), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 40/154 (25%), Positives = 62/154 (40%), Gaps = 19/154 (12%)
Query: 102 RKKVTIFFGTQTGTAEGFAKALGEE-AKARYEKTRFKIVDLDDYAADDDEYEEKLKKEDV 160
+ K I +G+ TG E A+ + E A A YE +D A E + D+
Sbjct: 218 QAKALIVYGSTTGNTEYTAETIARELADAGYE--------VDSRDAASVEAGGLFEGFDL 269
Query: 161 AFFFLATYGDG--EPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKVAKV 218
+T+GD E D+ + E +G K FG G+ +E+F
Sbjct: 270 VLLGCSTWGDDSIELQDDFIPLFDSLEETGAQGR-----KVACFGCGDSSWEYFCGAVDA 324
Query: 219 VDDILVEQGAQRLVQVGL--GDDDQCIEDDFTAW 250
+++ L GA+ +VQ GL D + DD W
Sbjct: 325 IEEKLKNLGAE-IVQDGLRIDGDPRAARDDIVGW 357
>3F6S-A nrPDB
Length = 148
Score = 33.5 bits (75), Expect = 0.34, Method: Compositional matrix adjust.
Identities = 38/133 (28%), Positives = 53/133 (39%), Gaps = 16/133 (12%)
Query: 104 KVTIFFGTQTGTAEGFAKALGEE-AKARYEKTRFKIVDLDDYAADDDEYEEKLKKEDVAF 162
KV I FG+ TG E A+ L E A +E T A D E D
Sbjct: 3 KVLIVFGSSTGNTESIAQKLEELIAAGGHEVTLLN--------AADASAENLADGYDAVL 54
Query: 163 FFLATYG--DGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKVAKVVD 220
F + +G D E D+ F F E + G L K F G+++YEHF ++
Sbjct: 55 FGCSAWGMEDLEMQDD---FLSLFEEFDRIG--LAGRKVAAFASGDQEYEHFCGAVPAIE 109
Query: 221 DILVEQGAQRLVQ 233
+ E GA + +
Sbjct: 110 ERAKELGATIIAE 122
>2V5U-A nrPDB
Length = 169
Score = 33.5 bits (75), Expect = 0.35, Method: Composition-based stats.
Identities = 15/46 (32%), Positives = 28/46 (60%), Gaps = 4/46 (8%)
Query: 103 KKVTIFFGTQTGTAEGFAKAL----GEEAKARYEKTRFKIVDLDDY 144
KK+ +F+GTQTG E A+ + G + ++ ++ ++ DL+DY
Sbjct: 2 KKIGLFYGTQTGKTESVAEIIRDEFGNDVVTLHDVSQAEVTDLNDY 47
>1AG9-A nrPDB
Length = 175
Score = 32.7 bits (73), Expect = 0.53, Method: Composition-based stats.
Identities = 39/170 (22%), Positives = 67/170 (39%), Gaps = 36/170 (21%)
Query: 107 IFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYEEKLKKEDVAFFFLA 166
IFFG+ TG E AK + ++ + D+ D A +E L+ D+ +
Sbjct: 5 IFFGSDTGNTENIAKMIQKQLGK-------DVADVHDIAKSS---KEDLEAYDILLLGIP 54
Query: 167 TYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQ--YEHFNKVAKVVDDILV 224
T+ GE + F+ E + G+ + +FG G+++ E+F + DI+
Sbjct: 55 TWYYGEAQCDWDDFFPTLEEIDFNGKLV-----ALFGCGDQEDYAEYFCDALGTIRDIIE 109
Query: 225 EQGAQRL-----------VQVGLGDDDQCI--------EDDFTAWREALW 255
+GA + GL DDD + + + TA R W
Sbjct: 110 PRGATIVGHWPTAGYHFEASKGLADDDHFVGLAIDEDRQPELTAERVEKW 159
>1CZN-A nrPDB
Length = 169
Score = 32.7 bits (73), Expect = 0.60, Method: Composition-based stats.
Identities = 31/128 (24%), Positives = 54/128 (42%), Gaps = 16/128 (12%)
Query: 104 KVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYEEKLKKEDVAFF 163
K+ +F+GTQTG + A+++ +E IVDL+D A D L D
Sbjct: 2 KIGLFYGTQTGVTQTIAESIQQEFGGE------SIVDLNDIANAD---ASDLNAYDYLII 52
Query: 164 FLATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNR--QYEHFNKVAKVVDD 221
T+ GE + Y N +G+ K FG G++ ++F ++++
Sbjct: 53 GCPTWNVGELQSDWEGIYDDLDSVNFQGK-----KVAYFGAGDQVGYSDNFQDAMGILEE 107
Query: 222 ILVEQGAQ 229
+ G+Q
Sbjct: 108 KISSLGSQ 115
>1KRH-A nrPDB
Length = 338
Score = 32.7 bits (73), Expect = 0.61, Method: Compositional matrix adjust.
Identities = 22/57 (38%), Positives = 30/57 (52%), Gaps = 5/57 (8%)
Query: 558 DSKVPIIMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEEEL 614
D K P++M+ GTG+APF LQ L + G E P L FG + D + E+L
Sbjct: 208 DVKRPVLMLAGGTGIAPFLSMLQ---VLEQKGSE-HPVRLVFGV-TQDCDLVALEQL 259
>5F1Q-A nrPDB
Length = 543
Score = 31.6 bits (70), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 40/166 (24%), Positives = 68/166 (40%), Gaps = 21/166 (12%)
Query: 310 QHPYKANVAVKRELHTPESDRSCIHLEFDIAGSGLTYETGDHVGVLCDNLSETVDEALRL 369
Q PY N +R +SD + I ++ I +TYE G+++ D ETV
Sbjct: 382 QRPYNPNA--RRMAEMIQSDWAKIGVKAKI----VTYEWGEYLKRAKDGEHETVMMGWTG 435
Query: 370 LDMSPD----TYFSLHAEKEDGTPISSSLPPPFPPC----------NLRTALTRYACLLS 415
+ PD T FS A K+ G+ S PF + R AL + A ++
Sbjct: 436 DNGDPDNFFATLFSCDAAKQ-GSNYSKWCYKPFEDLIQPARAEADHDKRVALYKQAQVVM 494
Query: 416 SPKKSALVALAAHASDPTEAERLKHLASPAGKDEYSKWVVESQRSL 461
+ + AL+ + +P E ++ P GK + +++ +L
Sbjct: 495 NEQAPALIIAHSTVYEPVRKEVKGYVVDPLGKHHFDNVSLDAGENL 540
>5YOB-A nrPDB
Length = 148
Score = 31.6 bits (70), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 42/152 (27%), Positives = 63/152 (41%), Gaps = 19/152 (12%)
Query: 104 KVTIFFGTQTGTAEGFAKALGEE-AKARYEKTRFKIVDLDDYAADDDEYEEKLKKEDVAF 162
K I +G+ TG E A+ + E A A YE VD D A+ E + D+
Sbjct: 3 KALIVYGSTTGNTEYTAETIARELADAGYE------VDSRDAASV--EAGGLFEGFDLVL 54
Query: 163 FFLATYGDG--EPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKVAKVVD 220
+T+GD E D+ + E +G K FG G+ +E+F ++
Sbjct: 55 LGCSTWGDDSIELQDDFIPLFDSLEETGAQGR-----KVACFGCGDSSWEYFCGAVDAIE 109
Query: 221 DILVEQGAQRLVQVGL--GDDDQCIEDDFTAW 250
+ L GA+ +VQ GL D + DD W
Sbjct: 110 EKLKNLGAE-IVQDGLRIDGDPRAARDDIVGW 140
>3KAQ-A nrPDB
Length = 147
Score = 31.2 bits (69), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 37/135 (27%), Positives = 59/135 (43%), Gaps = 20/135 (14%)
Query: 104 KVTIFFGTQTGTAEGFAKALGE-EAKARYEKTRFKIVDLDDYAADD--DEYEEKLKKEDV 160
KV I FG+ TG E A+ L E A +E T +++ + +AD+ D Y D
Sbjct: 2 KVLILFGSSTGNTESIAQKLEELVAAGGHEVT---LLNAAEASADNLADGY-------DA 51
Query: 161 AFFFLATYG--DGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKVAKV 218
+ +G D E D+ F F E + G LK K F G+ +YEH+
Sbjct: 52 VLMGCSAWGMEDLELQDD---FAPLFDEMENMG--LKGKKLAAFASGDMEYEHYCGAVPA 106
Query: 219 VDDILVEQGAQRLVQ 233
+++ GA+ + +
Sbjct: 107 IEEKARGLGAEVICE 121
>5OGX-A nrPDB
Length = 336
Score = 31.2 bits (69), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 16/37 (43%), Positives = 21/37 (56%), Gaps = 3/37 (8%)
Query: 551 SNFKLP---SDSKVPIIMIGPGTGLAPFRGFLQERLA 584
+F LP D P+++IG GTGLAP G + LA
Sbjct: 195 GDFHLPPPDEDDGGPMVLIGGGTGLAPLVGIARTALA 231
>1DPE-A nrPDB
Length = 507
Score = 31.2 bits (69), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 35/160 (21%), Positives = 62/160 (38%), Gaps = 19/160 (11%)
Query: 310 QHPYKANVAVKRELHTPESDRSCIHLEFDIAGSGLTYETGDHVGVLCDNLSETVDEALRL 369
Q PY N +R ++D + + ++ I +TYE G+++ D +TV
Sbjct: 354 QRPYNPNA--RRMAEMIQADWAKVGVQAKI----VTYEWGEYLKRAKDGEHQTVMMGWTG 407
Query: 370 LDMSPDTYFSLH---AEKEDGTPISSSLPPPFPPC----------NLRTALTRYACLLSS 416
+ PD +F+ A E G+ S PF N R L + A ++
Sbjct: 408 DNGDPDNFFATEFSCAASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMH 467
Query: 417 PKKSALVALAAHASDPTEAERLKHLASPAGKDEYSKWVVE 456
+ AL+ + +P E ++ P GK + +E
Sbjct: 468 DQAPALIIAHSTVFEPVRKEVKGYVVDPLGKHHFENVSIE 507
>4U9U-A nrPDB
Length = 281
Score = 31.2 bits (69), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 20/74 (27%), Positives = 38/74 (51%), Gaps = 9/74 (12%)
Query: 558 DSKVPIIMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEE----- 612
D+ ++ IG G G+AP R + ++L ++S ++ ++G R++R F E+
Sbjct: 144 DTDAEMVFIGGGAGMAPMRSHIFDQLKRLKSKRKMS---YWYGARSKREMFYVEDFDGLA 200
Query: 613 -ELQRFVESGALAE 625
E FV AL++
Sbjct: 201 AENDNFVWHCALSD 214
>4W5W-A nrPDB
Length = 391
Score = 30.8 bits (68), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 17/45 (37%), Positives = 28/45 (62%), Gaps = 5/45 (11%)
Query: 593 GPSVLFFGCRNRRMDFIYEEELQRFVESGALAELS--VAFSREGP 635
G S+ FFG R +Y++E+++FVES + ++ + SREGP
Sbjct: 282 GQSIDFFGALRAR---VYDDEVRKFVESLGVEKIGKRLVNSREGP 323
>2YXG-A nrPDB
Length = 289
Score = 30.8 bits (68), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 16/54 (29%), Positives = 31/54 (57%), Gaps = 2/54 (3%)
Query: 602 RNRRMDFI-YEEELQRFVESGALAELSVAFSREGPTKEYVQH-KMMDKASDIWN 653
+N+ +DF EE + +E+G ++V + E PT + +H K+++K D+ N
Sbjct: 14 KNKEVDFDGLEENINFLIENGVSGIVAVGTTGESPTLSHEEHKKVIEKVVDVVN 67
>5IM2-A nrPDB
Length = 385
Score = 30.4 bits (67), Expect = 2.8, Method: Compositional matrix adjust.
Identities = 21/66 (31%), Positives = 27/66 (40%), Gaps = 9/66 (13%)
Query: 588 SGVELGPSVLFFGCRNRRMDFIYEEELQRFVESGALAELSVAFSREGPTKEYVQHKMMDK 647
SGV+LG L+F RR S ALA + AFS+ T H M
Sbjct: 9 SGVDLGTENLYFQSMQRR---------SLLKTSAALALTAPAFSQAAATVTLKFHTFMAP 59
Query: 648 ASDIWN 653
S++W
Sbjct: 60 QSNVWQ 65
>4EH1-A nrPDB
Length = 243
Score = 30.0 bits (66), Expect = 3.3, Method: Compositional matrix adjust.
Identities = 36/177 (20%), Positives = 74/177 (41%), Gaps = 23/177 (12%)
Query: 489 RFYSISSSPKIAETRIHVTCALVYEKMPTGRIHKGVCSTWMKNAVPYEKSENCSSAPIFV 548
R YS+S + E RI V ++ G + G+ S ++ N V + S ++
Sbjct: 55 RQYSLSHASNGREYRISV------KREGVGSDNPGLVSHYLHNNV-----KVGDSVKLYA 103
Query: 549 RQSNFKLPSDSKVPIIMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDF 608
+F + + P+++I G G P + L +SGV + C + +
Sbjct: 104 PAGDF-FYVERERPVVLISAGVGATPMQAILHTLAKQNKSGV-----TYLYACNSAKEHT 157
Query: 609 IYEEELQRFVESGALAELSVAFSREGPTKEYVQHKMMDKASDIWNMISQGAYLYVCG 665
+E Q + G + ++ + R+ + +Q +M + +++ I G + Y+CG
Sbjct: 158 FAQETAQLIAQQGWMQQV---WYRDESADDVLQGEM--QLAELILPIEDGDF-YLCG 208
>4P6V-F nrPDB
Length = 408
Score = 29.6 bits (65), Expect = 4.4, Method: Compositional matrix adjust.
Identities = 15/55 (27%), Positives = 31/55 (56%), Gaps = 3/55 (5%)
Query: 558 DSKVPIIMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEE 612
D+ ++ IG G G+AP R + ++L ++S ++ ++G R++R F E+
Sbjct: 271 DTDAEMVFIGGGAGMAPMRSHIFDQLKRLKSKRKMS---YWYGARSKREMFYVED 322
>3OZU-A nrPDB
Length = 403
Score = 29.3 bits (64), Expect = 5.8, Method: Compositional matrix adjust.
Identities = 46/178 (25%), Positives = 66/178 (37%), Gaps = 37/178 (20%)
Query: 443 SPAGKDEYSKWVVESQRSLLEVMAEF---PSAKPPLGVF----FAGVA---PRL---QPR 489
P G + +V+ +R +V+ F P+ P+ F + VA P L Q R
Sbjct: 147 QPGGWKGWRTFVIREKRPESDVITSFILEPADGGPVVNFEPGQYTSVAIDVPALGLQQIR 206
Query: 490 FYSISSSPKIAETRIHVTCALVYEKMP---TGRIHKGV-CSTWMKNAVPYEKSENCSSAP 545
YS+S P RI V + P + +H V +K A PY
Sbjct: 207 QYSLSDMPNGRSYRISVKREGGGPQPPGYVSNLLHDHVNVGDQVKLAAPY---------- 256
Query: 546 IFVRQSNFKLPSDSKVPIIMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRN 603
+F + D+K PI++I G GL P L+ L V V G RN
Sbjct: 257 -----GSFHIDVDAKTPIVLISGGVGLTPMVSMLKVALQAPPRQV-----VFVHGARN 304
>3R0X-A nrPDB
Length = 448
Score = 29.3 bits (64), Expect = 6.2, Method: Compositional matrix adjust.
Identities = 17/71 (23%), Positives = 36/71 (50%), Gaps = 2/71 (2%)
Query: 266 GDTAVATPYTAAVLEYRVSIHDSEDAKFNDINMANGNGYTVFDAQHPYKANVAVKRELHT 325
G+ ++ +A + ++V++H S DA+ +G TV + + Y VAV++
Sbjct: 167 GNLGLSIGIMSACIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEDDY--GVAVEQGRKA 224
Query: 326 PESDRSCIHLE 336
+SD +C ++
Sbjct: 225 AQSDPNCFFID 235
>3SS9-X nrPDB
Length = 442
Score = 28.9 bits (63), Expect = 7.3, Method: Compositional matrix adjust.
Identities = 22/101 (21%), Positives = 46/101 (45%), Gaps = 12/101 (11%)
Query: 243 IEDDFTAWREALWPELDTILRE-------EGDTAVATPYTAAVLEYRVSIHDSEDAKFND 295
++DD++ + L PE + G+ ++ +A + ++V++H S DA+
Sbjct: 142 LDDDYS---KLLSPEFKQFFSQYSIAVGSTGNLGLSIGIMSARIGFKVTVHMSADARAWK 198
Query: 296 INMANGNGYTVFDAQHPYKANVAVKRELHTPESDRSCIHLE 336
+G TV + + Y VAV+ +SD +C ++
Sbjct: 199 KAKLRSHGVTVVEYEQDY--GVAVEEGRKAAQSDPNCFFID 237
>3WBE-A nrPDB
Length = 489
Score = 28.5 bits (62), Expect = 9.4, Method: Compositional matrix adjust.
Identities = 27/106 (25%), Positives = 43/106 (40%), Gaps = 18/106 (16%)
Query: 193 WLKNLKYGVFGLGNRQYEHFNKVAKVVDDILVEQGAQRLVQVGLGDDDQCIEDDFTAWRE 252
W + GV + +H+NK+ D L+ +G Q V + D Q +ED + W +
Sbjct: 94 WSRIYPNGVGQVNQAGIDHYNKLI----DALLAKGIQPYVTLYHWDLPQALEDKYKGWLD 149
Query: 253 -------ALWPELDTILREEGD-----TAVATPYTAAVLEYRVSIH 286
A + E T RE GD + P+T A+ Y +
Sbjct: 150 RQIVDDFAAYAE--TCFREFGDRVKHWITLNQPHTVAIQGYDAGLQ 193
Searching..................................................done
Results from round 2
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
5GXU-A nrPDB 929 0.0
3QFR-A nrPDB 856 0.0
6J79-A nrPDB 845 0.0
3ES9-A nrPDB 845 0.0
3FJO-A nrPDB 822 0.0
1TLL-A nrPDB 660 0.0
2BN4-A nrPDB 639 0.0
6EFV-A nrPDB 609 e-174
2B5O-A nrPDB 232 4e-61
1B1C-A nrPDB 214 9e-56
3HR4-A nrPDB 162 5e-40
1BVY-F nrPDB 156 4e-38
4H2D-A nrPDB 148 8e-36
1YKG-A nrPDB 141 1e-33
2M6S-A nrPDB 124 9e-29
5LJI-A nrPDB 103 2e-22
Sequences not found previously or not previously below threshold:
2HNA-A nrPDB 81 2e-15
4OXX-A nrPDB 79 6e-15
5B3K-A nrPDB 77 2e-14
5V57-A nrPDB 77 3e-14
5XRA-A nrPDB 77 3e-14
5ZKP-A nrPDB 76 4e-14
6GAQ-A nrPDB 76 5e-14
4HEQ-A nrPDB 74 2e-13
5YOB-A nrPDB 74 2e-13
5VEG-A nrPDB 72 9e-13
6FSI-A nrPDB 64 2e-10
3F6S-A nrPDB 63 6e-10
3KAQ-A nrPDB 59 9e-09
1KRH-A nrPDB 55 1e-07
3OZU-A nrPDB 50 3e-06
5OGX-A nrPDB 50 4e-06
2FCR-A nrPDB 49 7e-06
1CZN-A nrPDB 48 1e-05
2V5U-A nrPDB 48 2e-05
4EH1-A nrPDB 48 2e-05
2WC1-A nrPDB 45 1e-04
3W2G-A nrPDB 44 2e-04
1YOB-A nrPDB 44 2e-04
1UMK-A nrPDB 44 2e-04
2R6H-A nrPDB 43 5e-04
5THX-A nrPDB 42 0.001
4B4D-A nrPDB 42 0.001
1AG9-A nrPDB 41 0.001
2BMV-A nrPDB 41 0.003
1A8P-A nrPDB 37 0.020
4G1B-A nrPDB 37 0.020
6O0A-A nrPDB 37 0.023
4U9U-A nrPDB 37 0.032
4P6V-F nrPDB 37 0.032
4WQM-A nrPDB 36 0.042
2PIA-A nrPDB 36 0.054
2VNH-A nrPDB 35 0.091
3FPK-A nrPDB 34 0.27
1TLB-A nrPDB 34 0.31
2QDX-A nrPDB 33 0.46
1FDR-A nrPDB 33 0.47
1TK1-A nrPDB 32 1.2
1GVH-A nrPDB 32 1.2
5MWL-A nrPDB 31 1.4
2EIX-A nrPDB 31 1.5
6F4A-A nrPDB 31 1.5
5UFA-A nrPDB 31 1.6
4FK8-A nrPDB 31 2.0
2RCQ-A nrPDB 31 2.3
5J5Z-A nrPDB 31 2.3
6D35-A nrPDB 30 3.4
1EII-A nrPDB 30 4.7
>5GXU-A nrPDB
Length = 640
Score = 929 bits (2401), Expect = 0.0, Method: Composition-based stats.
Identities = 639/639 (100%), Positives = 639/639 (100%)
Query: 73 RRSGSGNSKRVEPLKPLVIKPREEEIDDGRKKVTIFFGTQTGTAEGFAKALGEEAKARYE 132
RRSGSGNSKRVEPLKPLVIKPREEEIDDGRKKVTIFFGTQTGTAEGFAKALGEEAKARYE
Sbjct: 2 RRSGSGNSKRVEPLKPLVIKPREEEIDDGRKKVTIFFGTQTGTAEGFAKALGEEAKARYE 61
Query: 133 KTRFKIVDLDDYAADDDEYEEKLKKEDVAFFFLATYGDGEPTDNAARFYKWFTEGNDRGE 192
KTRFKIVDLDDYAADDDEYEEKLKKEDVAFFFLATYGDGEPTDNAARFYKWFTEGNDRGE
Sbjct: 62 KTRFKIVDLDDYAADDDEYEEKLKKEDVAFFFLATYGDGEPTDNAARFYKWFTEGNDRGE 121
Query: 193 WLKNLKYGVFGLGNRQYEHFNKVAKVVDDILVEQGAQRLVQVGLGDDDQCIEDDFTAWRE 252
WLKNLKYGVFGLGNRQYEHFNKVAKVVDDILVEQGAQRLVQVGLGDDDQCIEDDFTAWRE
Sbjct: 122 WLKNLKYGVFGLGNRQYEHFNKVAKVVDDILVEQGAQRLVQVGLGDDDQCIEDDFTAWRE 181
Query: 253 ALWPELDTILREEGDTAVATPYTAAVLEYRVSIHDSEDAKFNDINMANGNGYTVFDAQHP 312
ALWPELDTILREEGDTAVATPYTAAVLEYRVSIHDSEDAKFNDINMANGNGYTVFDAQHP
Sbjct: 182 ALWPELDTILREEGDTAVATPYTAAVLEYRVSIHDSEDAKFNDINMANGNGYTVFDAQHP 241
Query: 313 YKANVAVKRELHTPESDRSCIHLEFDIAGSGLTYETGDHVGVLCDNLSETVDEALRLLDM 372
YKANVAVKRELHTPESDRSCIHLEFDIAGSGLTYETGDHVGVLCDNLSETVDEALRLLDM
Sbjct: 242 YKANVAVKRELHTPESDRSCIHLEFDIAGSGLTYETGDHVGVLCDNLSETVDEALRLLDM 301
Query: 373 SPDTYFSLHAEKEDGTPISSSLPPPFPPCNLRTALTRYACLLSSPKKSALVALAAHASDP 432
SPDTYFSLHAEKEDGTPISSSLPPPFPPCNLRTALTRYACLLSSPKKSALVALAAHASDP
Sbjct: 302 SPDTYFSLHAEKEDGTPISSSLPPPFPPCNLRTALTRYACLLSSPKKSALVALAAHASDP 361
Query: 433 TEAERLKHLASPAGKDEYSKWVVESQRSLLEVMAEFPSAKPPLGVFFAGVAPRLQPRFYS 492
TEAERLKHLASPAGKDEYSKWVVESQRSLLEVMAEFPSAKPPLGVFFAGVAPRLQPRFYS
Sbjct: 362 TEAERLKHLASPAGKDEYSKWVVESQRSLLEVMAEFPSAKPPLGVFFAGVAPRLQPRFYS 421
Query: 493 ISSSPKIAETRIHVTCALVYEKMPTGRIHKGVCSTWMKNAVPYEKSENCSSAPIFVRQSN 552
ISSSPKIAETRIHVTCALVYEKMPTGRIHKGVCSTWMKNAVPYEKSENCSSAPIFVRQSN
Sbjct: 422 ISSSPKIAETRIHVTCALVYEKMPTGRIHKGVCSTWMKNAVPYEKSENCSSAPIFVRQSN 481
Query: 553 FKLPSDSKVPIIMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEE 612
FKLPSDSKVPIIMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEE
Sbjct: 482 FKLPSDSKVPIIMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEE 541
Query: 613 ELQRFVESGALAELSVAFSREGPTKEYVQHKMMDKASDIWNMISQGAYLYVCGDAKGMAR 672
ELQRFVESGALAELSVAFSREGPTKEYVQHKMMDKASDIWNMISQGAYLYVCGDAKGMAR
Sbjct: 542 ELQRFVESGALAELSVAFSREGPTKEYVQHKMMDKASDIWNMISQGAYLYVCGDAKGMAR 601
Query: 673 DVHRSLHTIAQEQGSMDSTKAEGFVKNLQTSGRYLRDVW 711
DVHRSLHTIAQEQGSMDSTKAEGFVKNLQTSGRYLRDVW
Sbjct: 602 DVHRSLHTIAQEQGSMDSTKAEGFVKNLQTSGRYLRDVW 640
>3QFR-A nrPDB
Length = 618
Score = 856 bits (2211), Expect = 0.0, Method: Composition-based stats.
Identities = 245/624 (39%), Positives = 366/624 (58%), Gaps = 26/624 (4%)
Query: 96 EEIDDGRKKVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYEEKL 155
E++ + + +F+G+QTGTAE FA L ++A R D ++Y D ++
Sbjct: 12 EKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHR--YGMRGMSADPEEYDLADLSSLPEI 69
Query: 156 KKEDVAFFFLATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKV 215
+ F +ATYG+G+PTDNA FY W E + L +K+ VFGLGN+ YEHFN +
Sbjct: 70 DN-ALVVFCMATYGEGDPTDNAQDFYDWLQETDVD---LSGVKFAVFGLGNKTYEHFNAM 125
Query: 216 AKVVDDILVEQGAQRLVQVGLGDDDQCIEDDFTAWREALWPELDTILREEGDTAVATPYT 275
K VD L + GAQR+ ++GLGDDD +E+DF WRE WP + E AT
Sbjct: 126 GKYVDKRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEHFGVE-----ATGEE 180
Query: 276 AAVLEYRVSIH-DSEDAKFNDINMANGNGYT----VFDAQHPYKANVAVKRELHTPESDR 330
+++ +Y + +H D + AK M Y FDA++P+ A V R+L+ ++R
Sbjct: 181 SSIRQYELVVHTDIDAAKVYMGEMGRLKSYENQKPPFDAKNPFLAAVTTNRKLNQG-TER 239
Query: 331 SCIHLEFDIAGSGLTYETGDHVGVLCDNLSETVDEALRLLDMSPDTYFSLHAEKEDGTPI 390
+HLE DI+ S + YE+GDHV V N S V++ ++L D SL+ E+
Sbjct: 240 HLMHLELDISDSKIRYESGDHVAVYPANDSALVNQLGKILGADLDVVMSLNNLDEE---- 295
Query: 391 SSSLPPPFP-PCNLRTALTRYACLLSSPKKSALVALAAHASDPTEAERLKHLASPAG--K 447
S+ PFP P + RTALT Y + + P+ + L LA +AS+P+E E L+ +AS +G K
Sbjct: 296 -SNKKHPFPCPTSYRTALTYYLDITNPPRTNVLYELAQYASEPSEQELLRKMASSSGEGK 354
Query: 448 DEYSKWVVESQRSLLEVMAEFPSAKPPLGVFFAGVAPRLQPRFYSISSSPKIAETRIHVT 507
+ Y WVVE++R +L ++ + PS +PP+ + PRLQ +YSI+SS K+ +H+
Sbjct: 355 ELYLSWVVEARRHILAILQDCPSLRPPID-HLCELLPRLQAHYYSIASSSKVHPNSVHIC 413
Query: 508 CALVYEKMPTGRIHKGVCSTWMKNAVPYEKSENCSSAPIFVRQSNFKLPSDSKVPIIMIG 567
+V + GRI+KGV + W++ P ++ + P+FVR+S F+LP + P+IM+G
Sbjct: 414 AVVVEYETKAGRINKGVATNWLRAKEPAGENGGRALVPMFVRKSQFRLPFKATTPVIMVG 473
Query: 568 PGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEEELQRFVESGALAELS 627
PGTG+APF GF+QER L + G E+G ++L++GCR D++Y EEL +F GAL +L+
Sbjct: 474 PGTGVAPFIGFIQERAWLRQQGKEVGETLLYYGCRRSDEDYLYREELAQFHRDGALTQLN 533
Query: 628 VAFSREGPTKEYVQHKMMDKASDIWNMISQGAYLYVCGDAKGMARDVHRSLHTIAQEQGS 687
VAFSRE K YVQH + +W +I GA++YVCGDA+ MARDV + + I E G+
Sbjct: 534 VAFSREQSHKVYVQHLLKQDREHLWKLIEGGAHIYVCGDARNMARDVQNTFYDIVAELGA 593
Query: 688 MDSTKAEGFVKNLQTSGRYLRDVW 711
M+ +A ++K L T GRY DVW
Sbjct: 594 MEHAQAVDYIKKLMTKGRYSLDVW 617
>6J79-A nrPDB
Length = 871
Score = 845 bits (2183), Expect = 0.0, Method: Composition-based stats.
Identities = 248/625 (39%), Positives = 367/625 (58%), Gaps = 31/625 (4%)
Query: 96 EEIDDGRKKVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYEEKL 155
E++ + + +F+G+QTGTAE FA L ++A R D ++Y D ++
Sbjct: 268 EKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHR--YGMRGMSADPEEYDLADLSSLPEI 325
Query: 156 KKEDVAFFFLATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKV 215
K + F +ATYG+G+PTDNA FY W E + L +K+ VFGLGN+ YEHFN +
Sbjct: 326 DK-SLVVFCMATYGEGDPTDNAQDFYDWLQETDVD---LTGVKFAVFGLGNKTYEHFNAM 381
Query: 216 AKVVDDILVEQGAQRLVQVGLGDDDQCIEDDFTAWREALWPELDTILREEGDTAVATPYT 275
K VD L + GAQR+ ++GLGDDD +E+DF WRE WP + E
Sbjct: 382 GKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEA--------- 432
Query: 276 AAVLEYRVSIHDSED-AKFNDINMANGNGYT----VFDAQHPYKANVAVKRELHTPESDR 330
+++ +Y + +H+ D AK M Y FDA++P+ A V R+L+ ++R
Sbjct: 433 SSIRQYELVVHEDMDVAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVTANRKLNQG-TER 491
Query: 331 SCIHLEFDIAGSGLTYETGDHVGVLCDNLSETVDEALRLLDMSPDTYFSLHAEKEDGTPI 390
+HLE DI+ S + YE+GDHV V N S V++ +L D SL+ E+
Sbjct: 492 HLMHLELDISDSKIRYESGDHVAVYPANDSALVNQIGEILGADLDVIMSLNNLDEE---- 547
Query: 391 SSSLPPPFP-PCNLRTALTRYACLLSSPKKSALVALAAHASDPTEAERLKHLASPAG--K 447
S+ PFP P RTALT Y + + P+ + L LA +AS+P+E E L +AS +G K
Sbjct: 548 -SNKKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGK 606
Query: 448 DEYSKWVVESQRSLLEVMAEFPSAKPPLGVFFAGVAPRLQPRFYSISSSPKIAETRIHVT 507
+ Y WVVE++R +L ++ ++PS +PP+ + PRLQ R+YSI+SS K+ +H+
Sbjct: 607 ELYLSWVVEARRHILAILQDYPSLRPPID-HLCELLPRLQARYYSIASSSKVHPNSVHIC 665
Query: 508 CALVYEKMPTGRIHKGVCSTWMKNAVPYEKSENCSSAPIFVRQSNFKLPSDSKVPIIMIG 567
V + +GR++KGV ++W++ P ++ + P+FVR+S F+LP S P+IM+G
Sbjct: 666 AVAVEYEAKSGRVNKGVATSWLRAKEPAGENGGRALVPMFVRKSQFRLPFKSTTPVIMVG 725
Query: 568 PGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEEELQRFVESGALAELS 627
PGTG+APF GF+QER L E G E+G ++L++GCR D++Y EEL RF + GAL +L+
Sbjct: 726 PGTGIAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLN 785
Query: 628 VAFSREGPTKEYVQHKMMDKASDIWNMISQ-GAYLYVCGDAKGMARDVHRSLHTIAQEQG 686
VAFSRE K YVQH + +W +I + GA++YVCGDA+ MA+DV + + I E G
Sbjct: 786 VAFSREQAHKVYVQHLLKRDREHLWKLIHEGGAHIYVCGDARNMAKDVQNTFYDIVAEFG 845
Query: 687 SMDSTKAEGFVKNLQTSGRYLRDVW 711
M+ T+A +VK L T GRY DVW
Sbjct: 846 PMEHTQAVDYVKKLMTKGRYSLDVW 870
>3ES9-A nrPDB
Length = 618
Score = 845 bits (2183), Expect = 0.0, Method: Composition-based stats.
Identities = 248/625 (39%), Positives = 367/625 (58%), Gaps = 31/625 (4%)
Query: 96 EEIDDGRKKVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYEEKL 155
E++ + + +F+G+QTGTAE FA L ++A R D ++Y D ++
Sbjct: 15 EKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHR--YGMRGMSADPEEYDLADLSSLPEI 72
Query: 156 KKEDVAFFFLATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKV 215
K + F +ATYG+G+PTDNA FY W E + L +K+ VFGLGN+ YEHFN +
Sbjct: 73 DK-SLVVFCMATYGEGDPTDNAQDFYDWLQETDVD---LTGVKFAVFGLGNKTYEHFNAM 128
Query: 216 AKVVDDILVEQGAQRLVQVGLGDDDQCIEDDFTAWREALWPELDTILREEGDTAVATPYT 275
K VD L + GAQR+ ++GLGDDD +E+DF WRE WP + E
Sbjct: 129 GKYVDQRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEFFGVEA--------- 179
Query: 276 AAVLEYRVSIHDSED-AKFNDINMANGNGYT----VFDAQHPYKANVAVKRELHTPESDR 330
+++ +Y + +H+ D AK M Y FDA++P+ A V R+L+ ++R
Sbjct: 180 SSIRQYELVVHEDMDVAKVYTGEMGRLKSYENQKPPFDAKNPFLAAVTANRKLNQG-TER 238
Query: 331 SCIHLEFDIAGSGLTYETGDHVGVLCDNLSETVDEALRLLDMSPDTYFSLHAEKEDGTPI 390
+HLE DI+ S + YE+GDHV V N S V++ +L D SL+ E+
Sbjct: 239 HLMHLELDISDSKIRYESGDHVAVYPANDSALVNQIGEILGADLDVIMSLNNLDEE---- 294
Query: 391 SSSLPPPFP-PCNLRTALTRYACLLSSPKKSALVALAAHASDPTEAERLKHLASPAG--K 447
S+ PFP P RTALT Y + + P+ + L LA +AS+P+E E L +AS +G K
Sbjct: 295 -SNKKHPFPCPTTYRTALTYYLDITNPPRTNVLYELAQYASEPSEQEHLHKMASSSGEGK 353
Query: 448 DEYSKWVVESQRSLLEVMAEFPSAKPPLGVFFAGVAPRLQPRFYSISSSPKIAETRIHVT 507
+ Y WVVE++R +L ++ ++PS +PP+ + PRLQ R+YSI+SS K+ +H+
Sbjct: 354 ELYLSWVVEARRHILAILQDYPSLRPPID-HLCELLPRLQARYYSIASSSKVHPNSVHIC 412
Query: 508 CALVYEKMPTGRIHKGVCSTWMKNAVPYEKSENCSSAPIFVRQSNFKLPSDSKVPIIMIG 567
V + +GR++KGV ++W++ P ++ + P+FVR+S F+LP S P+IM+G
Sbjct: 413 AVAVEYEAKSGRVNKGVATSWLRAKEPAGENGGRALVPMFVRKSQFRLPFKSTTPVIMVG 472
Query: 568 PGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEEELQRFVESGALAELS 627
PGTG+APF GF+QER L E G E+G ++L++GCR D++Y EEL RF + GAL +L+
Sbjct: 473 PGTGIAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELARFHKDGALTQLN 532
Query: 628 VAFSREGPTKEYVQHKMMDKASDIWNMISQ-GAYLYVCGDAKGMARDVHRSLHTIAQEQG 686
VAFSRE K YVQH + +W +I + GA++YVCGDA+ MA+DV + + I E G
Sbjct: 533 VAFSREQAHKVYVQHLLKRDREHLWKLIHEGGAHIYVCGDARNMAKDVQNTFYDIVAEFG 592
Query: 687 SMDSTKAEGFVKNLQTSGRYLRDVW 711
M+ T+A +VK L T GRY DVW
Sbjct: 593 PMEHTQAVDYVKKLMTKGRYSLDVW 617
>3FJO-A nrPDB
Length = 637
Score = 822 bits (2124), Expect = 0.0, Method: Composition-based stats.
Identities = 235/625 (37%), Positives = 355/625 (56%), Gaps = 33/625 (5%)
Query: 98 IDDGRKKVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYE-EKLK 156
+ + K + + +QTGTAE +AK +E A++ +L+ AD + Y+ E L
Sbjct: 34 VTENNKNYLVLYASQTGTAEDYAKKFSKELVAKF--------NLNVMCADVENYDFESLN 85
Query: 157 KEDVAF-FFLATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKV 215
V F++TYG+G+ D A F + N L NL+Y +FGLGN YE FN
Sbjct: 86 DVPVIVSIFISTYGEGDFPDGAVNFEDFIC--NAEAGALSNLRYNMFGLGNSTYEFFNGA 143
Query: 216 AKVVDDILVEQGAQRLVQVGLGDDDQCIED-DFTAWREALWPELDTILREEGDTAVATPY 274
AK + L GA RL ++G DD D D+ AW++++ L L E AT
Sbjct: 144 AKKAEKHLSAAGAIRLGKLGEADDGAGTTDEDYMAWKDSILEVLKDELGVE-----ATGE 198
Query: 275 TAAVLEYRVSIH-DSEDAKFNDINMANGNGYT----VFDAQHPYKANVAVKRELHTPESD 329
+++ +Y + +H D + AK M Y FDA++P+ A V R+L+ ++
Sbjct: 199 ESSIRQYELVVHTDIDAAKVYMGEMGRLKSYENQKPPFDAKNPFLAAVTTNRKLNQG-TE 257
Query: 330 RSCIHLEFDIAGSGLTYETGDHVGVLCDNLSETVDEALRLLDMSPDTYFSLHAEKEDGTP 389
R +HLE DI+ S + YE+GDHV V N S V++ ++L D SL+ E+
Sbjct: 258 RHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQLGKILGADLDVVMSLNNLDEE--- 314
Query: 390 ISSSLPPPFP-PCNLRTALTRYACLLSSPKKSALVALAAHASDPTEAERLKHLASPAG-- 446
S+ PFP P + RTALT Y + + P+ + L LA +AS+P+E E L+ +AS +G
Sbjct: 315 --SNKKHPFPCPTSYRTALTYYLDITNPPRTNVLYELAQYASEPSEQELLRKMASSSGEG 372
Query: 447 KDEYSKWVVESQRSLLEVMAEFPSAKPPLGVFFAGVAPRLQPRFYSISSSPKIAETRIHV 506
K+ Y WVVE++R +L ++ + PS +PP+ + PRLQ R+YSI+SS K+ +H+
Sbjct: 373 KELYLSWVVEARRHILAILQDCPSLRPPID-HLCELLPRLQARYYSIASSSKVHPNSVHI 431
Query: 507 TCALVYEKMPTGRIHKGVCSTWMKNAVPYEKSENCSSAPIFVRQSNFKLPSDSKVPIIMI 566
+V + GRI+KGV + W++ P ++ + P+FVR+S F+LP + P+IM+
Sbjct: 432 CAVVVEYETKAGRINKGVATNWLRAKEPAGENGGRALVPMFVRKSQFRLPFKATTPVIMV 491
Query: 567 GPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEEELQRFVESGALAEL 626
GPGTG+APF GF+QER L + G E+G ++L++GCR D++Y EEL +F GAL +L
Sbjct: 492 GPGTGVAPFIGFIQERAWLRQQGKEVGETLLYYGCRRSDEDYLYREELAQFHRDGALTQL 551
Query: 627 SVAFSREGPTKEYVQHKMMDKASDIWNMISQGAYLYVCGDAKGMARDVHRSLHTIAQEQG 686
+VAFSRE K YVQH + +W +I GA++YVCGDA+ MARDV + + I E G
Sbjct: 552 NVAFSREQSHKVYVQHLLKQDREHLWKLIEGGAHIYVCGDARNMARDVQNTFYDIVAELG 611
Query: 687 SMDSTKAEGFVKNLQTSGRYLRDVW 711
+M+ +A ++K L T GRY DVW
Sbjct: 612 AMEHAQAVDYIKKLMTKGRYSLDVW 636
>1TLL-A nrPDB
Length = 688
Score = 660 bits (1702), Expect = 0.0, Method: Composition-based stats.
Identities = 190/668 (28%), Positives = 305/668 (45%), Gaps = 82/668 (12%)
Query: 102 RKKVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYE-EKLKKEDV 160
R K TI + T+TG ++ +AK L E K + D A +EY+ L+ E +
Sbjct: 11 RVKATILYATETGKSQAYAKTLCEIFKHAF----------DAKAMSMEEYDIVHLEHEAL 60
Query: 161 AFFFLATYGDGEPTDNAARFYKWFTEGN-------------------------------- 188
+T+G+G+P +N +F E
Sbjct: 61 VLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVQEERKSYKVRFNSVSSYSDSRKSSGDG 120
Query: 189 -------DRGEWLKNLKYGVFGLGNRQYEHFNKVAKVVDDILVEQGAQRLVQVGLGDDDQ 241
+ L N+++ VFGLG+R Y HF VD +L E G +R++++ GD+
Sbjct: 121 PDLRDNFESTGPLANVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKMREGDELC 180
Query: 242 CIEDDFTAWREALWPELDTILREEGDTAVATPYTAAVLEYRVSIHDSEDAKFNDINMANG 301
E+ F W + ++ + D + P + + R + KF +A
Sbjct: 181 GQEEAFRTWAKKVFKAACDVFCVGDDVNIEKPNNSLISNDR----SWKRNKFRLTYVAEA 236
Query: 302 ----NGYTVFDAQHPYKANVAVKRELHTPESDRSCIHLEFDIAGSG-LTYETGDHVGVLC 356
G + + A + ++ L +P+S RS I + G+ L Y+ GDH+GV
Sbjct: 237 PDLTQGLSNVHKKRVSAARLLSRQNLQSPKSSRSTIFVRLHTNGNQELQYQPGDHLGVFP 296
Query: 357 DNLSETVDEAL-RLLDMSPDTY---FSLHAEKEDGTPISSSLPPP--FPPCNLRTALTRY 410
N + V+ + RL D P + + E+ + S+ PPC + A Y
Sbjct: 297 GNHEDLVNALIERLEDAPPANHVVKVEMLEERNTALGVISNWKDESRLPPCTIFQAFKYY 356
Query: 411 ACLLSSPKKSALVALAAHASDPTEAERLKHLASPAGKDEYSKWVVESQRSLLEVMAEFPS 470
+ + P L A+ A++ E +RL L G EY +W +++EV+ EFPS
Sbjct: 357 LDITTPPTPLQLQQFASLATNEKEKQRL--LVLSKGLQEYEEWKWGKNPTMVEVLEEFPS 414
Query: 471 AKPPLGVFFAGVAPRLQPRFYSISSSPKIAETRIHVTCALV--YEKMPTGRIHKGVCSTW 528
+ P + LQPR+YSISSSP + +H+T A+V + + G +H GVCS+W
Sbjct: 415 IQMPATLL-LTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYHTRDGEGPVHHGVCSSW 473
Query: 529 MKNAVPYEKSENCSSAPIFVRQS-NFKLPSDSKVPIIMIGPGTGLAPFRGFLQER-LALV 586
+ + + P FVR + +F LP + +VP I++GPGTG+APFR F Q+R +
Sbjct: 474 LN------RIQADDVVPCFVRGAPSFHLPRNPQVPCILVGPGTGIAPFRSFWQQRQFDIQ 527
Query: 587 ESGVELGPSVLFFGCRNRRMDFIYEEELQRFVESGALAELSVAFSREG-PTKEYVQHKMM 645
G+ P VL FGCR ++D IY EE + G EL A+SRE K+YVQ +
Sbjct: 528 HKGMNPCPMVLVFGCRQSKIDHIYREETLQAKNKGVFRELYTAYSREPDRPKKYVQDVLQ 587
Query: 646 DK-ASDIWNMI-SQGAYLYVCGDAKGMARDVHRSLHTIAQEQGSMDSTKAEGFVKNLQTS 703
++ A ++ + QG ++YVCGD MA DV +++ I +QG + A F+ L+
Sbjct: 588 EQLAESVYRALKEQGGHIYVCGDVT-MAADVLKAIQRIMTQQGKLSEEDAGVFISRLRDD 646
Query: 704 GRYLRDVW 711
RY D++
Sbjct: 647 NRYHEDIF 654
>2BN4-A nrPDB
Length = 682
Score = 639 bits (1648), Expect = 0.0, Method: Composition-based stats.
Identities = 213/665 (32%), Positives = 326/665 (49%), Gaps = 78/665 (11%)
Query: 98 IDDGRKKVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYE-EKLK 156
+ + K + + +QTGTAE +AK +E A++ +L+ AD + Y+ E L
Sbjct: 45 VTENNKNYLVLYASQTGTAEDYAKKFSKELVAKF--------NLNVMCADVENYDFESLN 96
Query: 157 KEDVAF-FFLATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKV 215
V F++TYG+G+ D A F + N L NL+Y +FGLGN YE FN
Sbjct: 97 DVPVIVSIFISTYGEGDFPDGAVNFEDFIC--NAEAGALSNLRYNMFGLGNSTYEFFNGA 154
Query: 216 AKVVDDILVEQGAQRLVQVGLGDDDQCIED-DFTAWREALWPEL-DTILREEGDTAVATP 273
AK + L GA RL ++G DD D D+ AW++++ L D + +E + +
Sbjct: 155 AKKAEKHLSAAGAIRLGKLGEADDGAGTTDEDYMAWKDSILEVLKDELHLDEQEAKFTSQ 214
Query: 274 YTAAVLEYRV--------SIHDSEDAKFNDINMANGNGYTVFDAQHPYKANVAVKRELHT 325
+ VL S H + N A+G FD PY A + REL +
Sbjct: 215 FQYTVLNEITDSMSLGEPSAHYLPSHQLN--RNADGIQLGPFDLSQPYIAPIVKSRELFS 272
Query: 326 PESDRSCIHLEFDIAGSGLTYETGDHVGVLCDNLSETVDEALRLLDMSPDTYFSLHAEKE 385
+DR+CIH EFD++GS + Y TGDH+ V N E V++ L + ++ P+T F L
Sbjct: 273 -SNDRNCIHSEFDLSGSNIKYSTGDHLAVWPSNPLEKVEQFLSIFNLDPETIFDLK---- 327
Query: 386 DGTPISSSLPPPFP-PCNLRTALTRYACLLSSPKKSALVALAAHASDPTEAERLKHLASP 444
P+ ++ PFP P + A+ Y + + +L A + E+L L
Sbjct: 328 ---PLDPTVKVPFPTPTTIGAAIKHYLEITGPVSRQLFSSLIQFAPNADVKEKLTLL--S 382
Query: 445 AGKDEYSKWVVESQRSLLEVMAEFPSAKP----PLGVFFAGVAPRLQPRFYSISSSPKIA 500
KD+++ + ++ + + P+ F P++ PR+YSISSS
Sbjct: 383 KDKDQFAVEITSKYFNIADALKYLSDGAKWDTVPMQ-FLVESVPQMTPRYYSISSSSLSE 441
Query: 501 ETRIHVTCALVYEKMPTGRIHK-----GVCSTWMKNAVPYEKSENCSSA----------- 544
+ +HVT + E P + GV + ++N + + N +
Sbjct: 442 KQTVHVTSIV--ENFPNPELPDAPPVVGVTTNLLRNIQLAQNNVNIAETNLPVHYDLNGP 499
Query: 545 ---------PIFVRQSNFKLPSDSKVPIIMIGPGTGLAPFRGFLQERLALVES------G 589
P+ VR+SNF+LPS+ P+IMIGPGTG+APFRGF++ER+A +ES
Sbjct: 500 RKLFANYKLPVHVRRSNFRLPSNPSTPVIMIGPGTGVAPFRGFIRERVAFLESQKKGGNN 559
Query: 590 VELGPSVLFFGCRNRRMDFIYEEELQRFVE--SGALAELSVAFSREGPTK-EYVQHKMMD 646
V LG +LF+G RN DF+Y++E + + G+ E+ VA SR TK YVQ K+ D
Sbjct: 560 VSLGKHILFYGSRNTD-DFLYQDEWPEYAKKLDGSF-EMVVAHSRLPNTKKVYVQDKLKD 617
Query: 647 KASDIWNMISQGAYLYVCGDAKGMARDVHRSLHTIAQEQGSMDSTKAEGFVKNLQTSGRY 706
++ MI+ GA++YVCGDAKGMA+ V +L I S+ + +A +K L+TSGRY
Sbjct: 618 YEDQVFEMINNGAFIYVCGDAKGMAKGVSTALVGILSRGKSITTDEATELIKMLKTSGRY 677
Query: 707 LRDVW 711
DVW
Sbjct: 678 QEDVW 682
>6EFV-A nrPDB
Length = 569
Score = 609 bits (1569), Expect = e-174, Method: Composition-based stats.
Identities = 178/612 (29%), Positives = 286/612 (46%), Gaps = 85/612 (13%)
Query: 104 KVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYEEKLKKEDVAFF 163
++TI +QTG A A+AL ++ A K K+V+ DY +++ E +
Sbjct: 39 EITIISASQTGNARRVAEALRDDLLAA--KLNVKLVNAGDYKF------KQIASEKLLIV 90
Query: 164 FLATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKVAKVVDDIL 223
+T G+GEP + A +K+ + + L+N + VF LG+ YE F + K D L
Sbjct: 91 VTSTQGEGEPPEEAVALHKFLF--SKKAPKLENTAFAVFSLGDSSYEFFCQSGKDFDSKL 148
Query: 224 VEQGAQRLVQVGLGDDDQCIEDDFTAWREALWPELDTILREEGDTAVATPYTAAVLEYRV 283
E G +RL+ R + D Y AA E+R
Sbjct: 149 AELGGERLLD-----------------------------RVDADV----EYQAAASEWRA 175
Query: 284 SIHDSEDAKFNDINMANGNGYT--VFDAQHPYKANVAVKRELHTPESDRSCIHLEFDIAG 341
+ D+ ++ + N + P A+++V +++ S++ H+E D+
Sbjct: 176 RVVDALKSRAPVVATGAVNEIHTSPYSKDAPLVASLSVNQKITGRNSEKDVRHIEIDLGD 235
Query: 342 SGLTYETGDHVGVLCDNLSETVDEALRLLDMSPDTYFSLHAEKEDGTPISSSLPPPFP-P 400
SGL Y+ GD +GV N V E + LL + D ++ + P++ +L F
Sbjct: 236 SGLRYQPGDALGVWYQNDPALVKELVELLWLKGDEPVTVEGKT---LPLNEALQWHFELT 292
Query: 401 CNLRTALTRYACLLSSPKKSALVALAAHASDPTEAERLKHLASPAGKDEYSKWVVESQRS 460
N + YA L S LV A +L+H A+ +V+
Sbjct: 293 VNTANIVENYATLTRSETLLPLVGDKA---------KLQHYAATTP-------IVD---- 332
Query: 461 LLEVMAEFPSAKPPLGVFFAGVAPRLQPRFYSISSSPKIAETRIHVTCALVYEKMPTGRI 520
M F A+ + P L PR YSI+SS E +HVT +V + GR
Sbjct: 333 ----MVRFSPAQLDAEALINLLRP-LTPRLYSIASSQAEVENEVHVTVGVVRYDV-EGRA 386
Query: 521 HKGVCSTWMKNAVPYEKSENCSSAPIFVRQS-NFKLPSDSKVPIIMIGPGTGLAPFRGFL 579
G S+++ + V E +F+ + NF+LP++ + P+IMIGPGTG+APFR F+
Sbjct: 387 RAGGASSFLADRV-----EEEGEVRVFIEHNDNFRLPANPETPVIMIGPGTGIAPFRAFM 441
Query: 580 QERLALVESGVELGPSVLFFGCRNRRMDFIYEEELQRFVESGALAELSVAFSREGPTKEY 639
Q+R A G + LFFG + DF+Y+ E QR+V+ G L + +A+SR+ K Y
Sbjct: 442 QQRAA----DEAPGKNWLFFGNPHFTEDFLYQVEWQRYVKEGVLTRIDLAWSRDQKEKVY 497
Query: 640 VQHKMMDKASDIWNMISQGAYLYVCGDAKGMARDVHRSLHTIAQEQGSMDSTKAEGFVKN 699
VQ K+ ++ +++W I+ GA++YVCGDA MA+DV ++L + E G MD+ A+ F+
Sbjct: 498 VQDKLREQGAELWRWINDGAHIYVCGDANRMAKDVEQALLEVIAEFGGMDTEAADEFLSE 557
Query: 700 LQTSGRYLRDVW 711
L+ RY RDV+
Sbjct: 558 LRVERRYQRDVY 569
>2B5O-A nrPDB
Length = 402
Score = 232 bits (591), Expect = 4e-61, Method: Composition-based stats.
Identities = 60/234 (25%), Positives = 110/234 (47%), Gaps = 21/234 (8%)
Query: 489 RFYSISSSPK--IAETRIHVTCA--LVYEKMPTGRIHKGVCSTWMKNAVPYEKSENCSSA 544
R YSI+S+ + + + C L Y+ +G GVCST++ N +P + +
Sbjct: 179 RLYSIASTRHGDMEDNKTVSLCVRQLEYQDPESGETVYGVCSTYLCN-LPVGTDDVKITG 237
Query: 545 PIFVRQSNFKLPSDSKVPIIMIGPGTGLAPFRGFLQERLALVESGVEL-GPSVLFFGCRN 603
P+ LP D ++M+ GTG+APFR FL + G + L FG
Sbjct: 238 PV---GKEMLLPDDEDATVVMLATGTGIAPFRAFLWRMFKEQHEDYKFKGKAWLIFGV-P 293
Query: 604 RRMDFIYEEELQRF-VESGALAELSVAFSREGPT----KEYVQHKMMDKASDIWNMISQ- 657
+ +Y+++ ++ E+ L+ A SRE T K YVQ ++ + A +++ MI +
Sbjct: 294 YTANILYKDDFEKMAAENPDNFRLTYAISREQKTADGGKVYVQSRVSEYADELFEMIQKP 353
Query: 658 GAYLYVCGDAKGMARDVHRSLHTIAQEQGSMDSTKAEGFVKNLQTSGRYLRDVW 711
++Y+CG KGM + + A+++G E ++++ R+ +V+
Sbjct: 354 NTHVYMCG-LKGMQPPIDETFTAEAEKRG----LNWEEMRRSMKKEHRWHVEVY 402
Score = 39.4 bits (90), Expect = 0.006, Method: Composition-based stats.
Identities = 24/161 (14%), Positives = 47/161 (29%), Gaps = 19/161 (11%)
Query: 307 FDAQHPYKANVAVKRELHTPESDRSCIHLEFDIAGSGLTYETGDHVGVL-CDNLSETVDE 365
+ + P+ EL + H+ FDI+ L Y G +G++
Sbjct: 117 YRPKTPFLGKCIENYELVDEGGSGTVRHVTFDISEGDLRYLEGQSIGIIPPGEDKNGKPH 176
Query: 366 ALRLLDMSPDTYFSLHAEKEDGTPISS-SLPPPFPPCNLRTALTRYAC----------LL 414
LRL ++ + + K + P + + Y C +
Sbjct: 177 KLRLYSIASTRHGDMEDNKTVSLCVRQLEYQDPESGETVYGVCSTYLCNLPVGTDDVKIT 236
Query: 415 SSPKKSALVALAAHASDPTEAERLKHLASPAGKDEYSKWVV 455
K L+ E + LA+ G + ++
Sbjct: 237 GPVGKEMLLPD-------DEDATVVMLATGTGIAPFRAFLW 270
>1B1C-A nrPDB
Length = 181
Score = 214 bits (545), Expect = 9e-56, Method: Composition-based stats.
Identities = 68/171 (39%), Positives = 97/171 (56%), Gaps = 6/171 (3%)
Query: 96 EEIDDGRKKVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYEEKL 155
E++ + + +F+G+QTGTAE FA L ++A R D ++Y D ++
Sbjct: 11 EKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHR--YGMRGMSADPEEYDLADLSSLPEI 68
Query: 156 KKEDVAFFFLATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKV 215
+ F +ATYG+G+PTDNA FY W E + L +K+ VFGLGN+ YEHFN +
Sbjct: 69 DN-ALVVFCMATYGEGDPTDNAQDFYDWLQETDVD---LSGVKFAVFGLGNKTYEHFNAM 124
Query: 216 AKVVDDILVEQGAQRLVQVGLGDDDQCIEDDFTAWREALWPELDTILREEG 266
K VD L + GAQR+ ++GLGDDD +E+DF WRE WP + E
Sbjct: 125 GKYVDKRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWPAVCEHFGVEA 175
>3HR4-A nrPDB
Length = 219
Score = 162 bits (409), Expect = 5e-40, Method: Composition-based stats.
Identities = 46/181 (25%), Positives = 71/181 (39%), Gaps = 12/181 (6%)
Query: 97 EIDDGRKKVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYEEKLK 156
+ R +VTI F T+TG +E A LG + K+V +D Y L+
Sbjct: 35 KTMASRVRVTILFATETGKSEALAWDLGALFSCAF---NPKVVCMDKYRLSC------LE 85
Query: 157 KEDVAFFFLATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKVA 216
+E + +T+G+G+ N + K + +Y VFGLG+ Y F A
Sbjct: 86 EERLLLVVTSTFGNGDCPGNGEKLKKSLFMLKELNNK---FRYAVFGLGSSMYPRFCAFA 142
Query: 217 KVVDDILVEQGAQRLVQVGLGDDDQCIEDDFTAWREALWPELDTILREEGDTAVATPYTA 276
+D L GA +L +G GD+ ED F +W + G + P
Sbjct: 143 HDIDQKLSHLGASQLTPMGEGDELSGQEDAFRSWAVQTFKAACETFDVRGKQHIQIPKLY 202
Query: 277 A 277
Sbjct: 203 T 203
>1BVY-F nrPDB
Length = 191
Score = 156 bits (393), Expect = 4e-38, Method: Composition-based stats.
Identities = 44/177 (24%), Positives = 84/177 (47%), Gaps = 13/177 (7%)
Query: 92 KPREEEIDDGRKKVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEY 151
K R++ + + + +G+ GTAEG A+ L + A ++ ++ LD +A +
Sbjct: 11 KVRKKAENAHNTPLLVLYGSNMGTAEGTARDLADIAMSK--GFAPQVATLDSHAGN---- 64
Query: 152 EEKLKKEDVAFFFLATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQY-E 210
L +E A+Y +G P DNA +F W + + + +K ++Y VFG G++ +
Sbjct: 65 ---LPREGAVLIVTASY-NGHPPDNAKQFVDWLDQAS--ADEVKGVRYSVFGCGDKNWAT 118
Query: 211 HFNKVAKVVDDILVEQGAQRLVQVGLGDDDQCIEDDFTAWREALWPELDTILREEGD 267
+ KV +D+ L +GA+ + G D E + WRE +W ++ + +
Sbjct: 119 TYQKVPAFIDETLAAKGAENIADRGEADASDDFEGTYEEWREHMWSDVAAYFNLDIE 175
>4H2D-A nrPDB
Length = 165
Score = 148 bits (373), Expect = 8e-36, Method: Composition-based stats.
Identities = 51/157 (32%), Positives = 75/157 (47%), Gaps = 10/157 (6%)
Query: 104 KVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYEEKLKKEDVAFF 163
++ + FG+QTGTA+ ++ LG EA+ R R + LD Y + L E + F
Sbjct: 9 QLLVLFGSQTGTAQDVSERLGREARRRRLGCRVQA--LDSYPVVN------LINEPLVIF 60
Query: 164 FLATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKVAKVVDDIL 223
AT G G+P DN F+++ N L + + V GLG+ Y FN VAK + L
Sbjct: 61 VCATTGQGDPPDNMKNFWRFIFRKNLPSTALCQMDFAVLGLGDSSYAKFNFVAKKLHRRL 120
Query: 224 VEQGAQRLVQVGLGDDDQCIEDDFTA--WREALWPEL 258
++ G L+ V LGDD + D W LW +
Sbjct: 121 LQLGGSALLPVCLGDDQHELGPDAAVDPWLRDLWDRV 157
>1YKG-A nrPDB
Length = 167
Score = 141 bits (355), Expect = 1e-33, Method: Composition-based stats.
Identities = 47/193 (24%), Positives = 77/193 (39%), Gaps = 43/193 (22%)
Query: 105 VTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYEEKLKKEDVAFFF 164
+TI +QTG A A+AL ++ A K K+V+ DY +++ E +
Sbjct: 12 ITIISASQTGNARRVAEALRDDLLAA--KLNVKLVNAGDYKF------KQIASEKLLIVV 63
Query: 165 LATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKVAKVVDDILV 224
+T G+GEP + A +K+ + + L+N + VF LG+ YE F + K D L
Sbjct: 64 TSTQGEGEPPEEAVALHKFLF--SKKAPKLENTAFAVFSLGDTSYEFFCQSGKDFDSKLA 121
Query: 225 EQGAQRLVQVGLGDDDQCIEDDFTAWREALWPELDTILREEGDTAVATPYTAAVLEYRVS 284
E G +RL+ R + D Y AA E+R
Sbjct: 122 ELGGERLLD-----------------------------RVDADV----EYQAAASEWRAR 148
Query: 285 IHDSEDAKFNDIN 297
+ D+ ++
Sbjct: 149 VVDALKSRAPVAA 161
>2M6S-A nrPDB
Length = 149
Score = 124 bits (312), Expect = 9e-29, Method: Composition-based stats.
Identities = 40/153 (26%), Positives = 66/153 (43%), Gaps = 15/153 (9%)
Query: 104 KVTIFFGTQTGTAEGFAKALGEEAKA-RYEKTRFKIVDLDDYAADDDEYEEKLKKEDVAF 162
++ IF GT G + A+ A ++ T F+ +L D+ D+Y
Sbjct: 3 EIGIFVGTMYGNSLLVAEEAEAILTAQGHKATVFEDPELSDWLPYQDKY---------VL 53
Query: 163 FFLATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKVAKVVDDI 222
+T G G+ D+ ++ D + NL+YGV LG+ Y +F K D +
Sbjct: 54 VVTSTTGQGDLPDSIVPLFQGI---KDSLGFQPNLRYGVIALGDSSYVNFCNGGKQFDAL 110
Query: 223 LVEQGAQRLVQVGLGDDDQCIEDDFTA--WREA 253
L EQ AQR+ ++ L D + E + + W E
Sbjct: 111 LQEQSAQRVGEMLLIDASENPEPETESNPWVEH 143
>5LJI-A nrPDB
Length = 148
Score = 103 bits (257), Expect = 2e-22, Method: Composition-based stats.
Identities = 39/141 (27%), Positives = 59/141 (41%), Gaps = 16/141 (11%)
Query: 107 IFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYEEKLKKEDVAFFFLA 166
I F + TG E A + ++ R + + A D + D+A
Sbjct: 6 IVFASMTGNTEEIADIVADKL--RDLGLDVDVDECTTVDASD------FLEADIAIVATY 57
Query: 167 TYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKVAKVVDDILVEQ 226
TYGDGE D FY+ + N G+ YGV G G+ Y+ F K D + V
Sbjct: 58 TYGDGELPDEMMDFYEDLADLNLNGKI-----YGVVGSGDTFYDEFCKAVDDFDRVFVST 112
Query: 227 GAQR---LVQVGLGDDDQCIE 244
GA++ V+V L +++ IE
Sbjct: 113 GAEKGSECVKVDLSAEEEDIE 133
>2HNA-A nrPDB
Length = 147
Score = 80.6 bits (197), Expect = 2e-15, Method: Composition-based stats.
Identities = 34/150 (22%), Positives = 61/150 (40%), Gaps = 17/150 (11%)
Query: 104 KVTIFFGTQTGTAEGFAKALGEEAK-ARYEKTRFKIVDLDDYAADDDEYEEKLKKEDVAF 162
+T+ G+ G AE A+ L E+ + A + L+D L +
Sbjct: 3 DITLISGSTLGGAEYVAEHLAEKLEEAGFTTETLHGPLLED-----------LPASGIWL 51
Query: 163 FFLATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKVAKVVDDI 222
+T+G G+ DN + FY+ E L +++G G+G+R+Y+ F ++
Sbjct: 52 VISSTHGAGDIPDNLSPFYEALQEQK---PDLSAVRFGAIGIGSREYDTFCGAIDKLEAE 108
Query: 223 LVEQGAQRLVQVGLGD--DDQCIEDDFTAW 250
L GA++ + + D ED W
Sbjct: 109 LKNSGAKQTGETLKINILDHDIPEDPAEEW 138
>4OXX-A nrPDB
Length = 162
Score = 79.1 bits (193), Expect = 6e-15, Method: Composition-based stats.
Identities = 40/159 (25%), Positives = 60/159 (37%), Gaps = 12/159 (7%)
Query: 104 KVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYEEKLKKEDVAFF 163
I +GT+TG AE A + + + + D+ A D + + F
Sbjct: 2 NALILYGTETGNAEACATTISQVLADTVDTKVHDLADMTPRAMLDSGAD-------LIVF 54
Query: 164 FLATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKVAKVVDDIL 223
ATYG+GE A F++ E L L++ VFGLG+ Y FN+ IL
Sbjct: 55 ATATYGEGEFAGGGAAFFETLRETK---PDLSGLRFAVFGLGDSYYTTFNQAGATAATIL 111
Query: 224 VEQGAQRLVQVGLGDDDQCIEDDFTA--WREALWPELDT 260
G ++ D + TA W + L T
Sbjct: 112 ASLGGTQVGDTARHDTSSGDDPAATAAEWAREILTALAT 150
>5B3K-A nrPDB
Length = 150
Score = 77.2 bits (188), Expect = 2e-14, Method: Composition-based stats.
Identities = 38/160 (23%), Positives = 56/160 (35%), Gaps = 16/160 (10%)
Query: 104 KVTIFFGTQTGTAEGFAKALGEEAKA-RYEKTRFKIVDLDDYAADDDEYEEKLKKEDVAF 162
KV I G+ GTAE A+ + A E + LD+ A E
Sbjct: 2 KVAILSGSVYGTAEEVARHAQKLLSAAGLEASHLPRASLDELKAFAPE---------AFL 52
Query: 163 FFLATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQY-EHFNKVAKVVDD 221
+T G GE DN Y + L GV GLG+ Y + F + V +
Sbjct: 53 VVTSTTGMGELPDNLQPLYYAIRDQ---LPAWHGLPGGVIGLGDSSYGDTFAGGGEQVRE 109
Query: 222 ILVEQGAQRLVQVGLGDDDQCI--EDDFTAWREALWPELD 259
+ E G + ++ + D + + E D W L
Sbjct: 110 LFGELGVREVLPMLRLDASETVTPETDAEPWLAEFAAALK 149
>5V57-A nrPDB
Length = 648
Score = 76.8 bits (187), Expect = 3e-14, Method: Composition-based stats.
Identities = 36/161 (22%), Positives = 60/161 (37%), Gaps = 17/161 (10%)
Query: 98 IDDGRKKVTIFFGTQTGTAEGFAKALGEE-AKARYEKTRFKIVDLDDYAADDDEYEEKLK 156
I K I +G+ TG E A+ + E A A Y ++D A E +
Sbjct: 372 IKSNHAKALIVYGSTTGNTEYTAETIARELADAGY--------EVDSRDAASVEAGGLFE 423
Query: 157 KEDVAFFFLATYGDG--EPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNK 214
D+ +T+GD E D+ + E +G + FG G+ +E+F
Sbjct: 424 GFDLVLLGCSTWGDDSIELQDDFIPLFDSLEETGAQGRKV-----ACFGCGDSSWEYFCG 478
Query: 215 VAKVVDDILVEQGAQRLVQVGLGD-DDQCIEDDFTAWREAL 254
+++ L GA+ + D D + DD W +
Sbjct: 479 AVDAIEEKLKNLGAEIVQDGLRIDGDPRAARDDIVGWAHDV 519
>5XRA-A nrPDB
Length = 438
Score = 76.8 bits (187), Expect = 3e-14, Method: Composition-based stats.
Identities = 37/172 (21%), Positives = 64/172 (37%), Gaps = 17/172 (9%)
Query: 104 KVTIFFGTQTGTAEGFAKALGEE-AKARYEKTRFKIVDLDDYAADDDEYEEKLKKEDVAF 162
K I +G+ TG E A+ + E A A Y ++D A E + D+
Sbjct: 210 KALIVYGSTTGNTEYTAETIARELADAGY--------EVDSRDAASVEAGGLFEGFDLVL 261
Query: 163 FFLATYGDG--EPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKVAKVVD 220
+T+GD E D+ + E +G + FG G+ +E+F ++
Sbjct: 262 LGCSTWGDDSIELQDDFIPLFDSLEETGAQGRKV-----ACFGCGDSSWEYFCGAVDAIE 316
Query: 221 DILVEQGAQRLVQVGLGD-DDQCIEDDFTAWREALWPELDTILREEGDTAVA 271
+ L GA+ + D D + DD W + + R + + A
Sbjct: 317 EKLKNLGAEIVQDGLRIDGDPRAARDDIVGWAHDVRGAIPDQARMDIELAKT 368
>5ZKP-A nrPDB
Length = 466
Score = 76.4 bits (186), Expect = 4e-14, Method: Composition-based stats.
Identities = 36/166 (21%), Positives = 63/166 (37%), Gaps = 17/166 (10%)
Query: 104 KVTIFFGTQTGTAEGFAKALGEE-AKARYEKTRFKIVDLDDYAADDDEYEEKLKKEDVAF 162
K I +G+ TG E A+ + E A A Y ++D A E + D+
Sbjct: 220 KALIVYGSTTGNTEYTAETIARELADAGY--------EVDSRDAASVEAGGLFEGFDLVL 271
Query: 163 FFLATYGDG--EPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKVAKVVD 220
+T+GD E D+ + E +G + FG G+ +E+F ++
Sbjct: 272 LGCSTWGDDSIELQDDFIPLFDSLEETGAQGRKV-----ACFGCGDSSWEYFCGAVDAIE 326
Query: 221 DILVEQGAQRLVQVGLGD-DDQCIEDDFTAWREALWPELDTILREE 265
+ L GA+ + D D + DD W + + + R +
Sbjct: 327 EKLKNLGAEIVQDGLRIDGDPRAARDDIVGWAHDVRGAIAEVKRRD 372
>6GAQ-A nrPDB
Length = 154
Score = 76.0 bits (185), Expect = 5e-14, Method: Composition-based stats.
Identities = 33/143 (23%), Positives = 60/143 (41%), Gaps = 13/143 (9%)
Query: 104 KVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYEEKLKKEDVAFF 163
K+ I + + +G E A L + + ++ + +++ A E+L D
Sbjct: 10 KILIAYASMSGNTESIA-DLIKVSLDAFDHEVV-LQEMEGMDA------EELLAYDGIIL 61
Query: 164 FLATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKVAKVVDDIL 223
T+GDGE A F+ + L K VFG G+ YE F + + ++ L
Sbjct: 62 GSYTWGDGELPFEAEDFHDDLENID-----LAGKKVAVFGSGDTAYELFCEAVTIFEERL 116
Query: 224 VEQGAQRLVQVGLGDDDQCIEDD 246
VE+GA+ + + + E+D
Sbjct: 117 VERGAELVQEGLKIELAPEDEED 139
>4HEQ-A nrPDB
Length = 146
Score = 74.1 bits (180), Expect = 2e-13, Method: Composition-based stats.
Identities = 31/157 (19%), Positives = 57/157 (36%), Gaps = 15/157 (9%)
Query: 104 KVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYEEKLKKEDVAFF 163
K I +G+ TG EG A+A+ + + +T V + Y+ V
Sbjct: 3 KALIVYGSTTGNTEGVAEAIAKTLNSEGMETTVVNVADVTAPGLAEGYD-------VVLL 55
Query: 164 FLATYGDGE--PTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKVAKVVDD 221
+T+GD E ++ Y+ + + + GVFG G+ Y +F V++
Sbjct: 56 GCSTWGDDEIELQEDFVPLYEDLDRAGLKDKKV-----GVFGCGDSSYTYFCGAVDVIEK 110
Query: 222 ILVEQGAQRLVQVGLGDDDQCIEDDFTAWREALWPEL 258
E GA + D + + W + +
Sbjct: 111 KAEELGATLVASSLKIDGEPDSAE-VLDWAREVLARV 146
>5YOB-A nrPDB
Length = 148
Score = 73.7 bits (179), Expect = 2e-13, Method: Composition-based stats.
Identities = 35/155 (22%), Positives = 59/155 (38%), Gaps = 17/155 (10%)
Query: 104 KVTIFFGTQTGTAEGFAKALGEE-AKARYEKTRFKIVDLDDYAADDDEYEEKLKKEDVAF 162
K I +G+ TG E A+ + E A A Y ++D A E + D+
Sbjct: 3 KALIVYGSTTGNTEYTAETIARELADAGY--------EVDSRDAASVEAGGLFEGFDLVL 54
Query: 163 FFLATYGDG--EPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKVAKVVD 220
+T+GD E D+ + E +G + FG G+ +E+F ++
Sbjct: 55 LGCSTWGDDSIELQDDFIPLFDSLEETGAQGRKV-----ACFGCGDSSWEYFCGAVDAIE 109
Query: 221 DILVEQGAQRLVQVGLGD-DDQCIEDDFTAWREAL 254
+ L GA+ + D D + DD W +
Sbjct: 110 EKLKNLGAEIVQDGLRIDGDPRAARDDIVGWAHDV 144
>5VEG-A nrPDB
Length = 178
Score = 71.8 bits (174), Expect = 9e-13, Method: Composition-based stats.
Identities = 30/140 (21%), Positives = 51/140 (36%), Gaps = 14/140 (10%)
Query: 107 IFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYEEKLKKEDVAFFFLA 166
+ + T TG E A + + K+ + + D ++ + D+
Sbjct: 35 VVYATMTGNNEEVANIVCDSL----TNLNVKVTESEISQTDVADFMKA----DILVVCAY 86
Query: 167 TYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQY-EHFNKVAKVVDDILVE 225
TY +G + FY + G+ YGV G G++ Y E+FN DD +
Sbjct: 87 TYDEGAMPEEGLDFYDDLQSTDLTGKV-----YGVAGSGDKFYGEYFNTTVDHFDDAFKK 141
Query: 226 QGAQRLVQVGLGDDDQCIED 245
GA + D + ED
Sbjct: 142 AGATSGAEKVKIDLEPYEED 161
>6FSI-A nrPDB
Length = 147
Score = 64.1 bits (154), Expect = 2e-10, Method: Composition-based stats.
Identities = 30/144 (20%), Positives = 56/144 (38%), Gaps = 15/144 (10%)
Query: 104 KVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYEEKLKKEDVAFF 163
K+ + F + +G E A + R +++ D L++ D
Sbjct: 2 KLVMIFASMSGNTEEMADHIA-------GVIRETENEIEVIDIMDSPEASILEQYDGIIL 54
Query: 164 FLATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKVAKVVDDIL 223
T+GDG+ D+ FY + L K VFG + Y + ++ + L
Sbjct: 55 GAYTWGDGDLPDDFLDFYDAMDSID-----LTGKKAAVFGSCDSAYPKYGVAVDILIEKL 109
Query: 224 VEQGAQRL---VQVGLGDDDQCIE 244
E+GA + ++V L +D+ +E
Sbjct: 110 QERGAAVVLEGLKVELTPEDEDVE 133
>3F6S-A nrPDB
Length = 148
Score = 62.5 bits (150), Expect = 6e-10, Method: Composition-based stats.
Identities = 36/157 (22%), Positives = 60/157 (38%), Gaps = 13/157 (8%)
Query: 104 KVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYEEKLKKEDVAFF 163
KV I FG+ TG E A+ L E A +++ D +A++ D F
Sbjct: 3 KVLIVFGSSTGNTESIAQKLEELIAAG--GHEVTLLNAADASAENLA-----DGYDAVLF 55
Query: 164 FLATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKVAKVVDDIL 223
+ +G + + E DR L K F G+++YEHF +++
Sbjct: 56 GCSAWGMEDL--EMQDDFLSLFEEFDRIG-LAGRKVAAFASGDQEYEHFCGAVPAIEERA 112
Query: 224 VEQGAQRLVQ--VGLGDDDQCIEDDFTAWREALWPEL 258
E GA + + GD E ++ E + +L
Sbjct: 113 KELGATIIAEGLKMEGDASNDPE-AVASFAEDVLKQL 148
>3KAQ-A nrPDB
Length = 147
Score = 58.7 bits (140), Expect = 9e-09, Method: Composition-based stats.
Identities = 35/159 (22%), Positives = 62/159 (38%), Gaps = 17/159 (10%)
Query: 104 KVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYEEKLKKEDVAFF 163
KV I FG+ TG E A+ L E A +++ + +AD+ D
Sbjct: 2 KVLILFGSSTGNTESIAQKLEELVAAG--GHEVTLLNAAEASADNLA-----DGYDAVLM 54
Query: 164 FLATYG--DGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQYEHFNKVAKVVDD 221
+ +G D E D+ A + +G+ L F G+ +YEH+ +++
Sbjct: 55 GCSAWGMEDLELQDDFAPLFDEMENMGLKGKKL-----AAFASGDMEYEHYCGAVPAIEE 109
Query: 222 ILVEQGAQRLVQ--VGLGDDDQCIEDDFTAWREALWPEL 258
GA+ + + GD D +A+ E + +L
Sbjct: 110 KARGLGAEVICEGLKIEGDASSD-PDAVSAFAEDVLKKL 147
>1KRH-A nrPDB
Length = 338
Score = 54.8 bits (130), Expect = 1e-07, Method: Composition-based stats.
Identities = 52/254 (20%), Positives = 88/254 (34%), Gaps = 37/254 (14%)
Query: 417 PKKSALVALAAHASDPTEAERLKHLASPAGKDEYSKWVVESQRSLLEVMAEFPSAKPPLG 476
P A+ + AS ++ H + E + L+ P G
Sbjct: 87 PTSDAVFQIQ--ASSEVCKTKIHHFEGTLARVENLSDSTITFDIQLDDGQ--PDIHFLAG 142
Query: 477 VFFAGVAPRLQ-PRFYSISSSPKIAETRIHVTCALVYEKMPTGRIHKGVCSTWMKNAVPY 535
+ P R YS SS P + V +P G++ S ++
Sbjct: 143 QYVNVTLPGTTETRSYSFSSQPG------NRLTGFVVRNVPQGKM-----SEYLSVQAKA 191
Query: 536 EKSENCSSAPIFVRQSNFKLPSDSKVPIIMIGPGTGLAPFRGFLQERLALVESGVELGPS 595
+ + P +F L D K P++M+ GTG+APF LQ ++E P
Sbjct: 192 G-DKMSFTGPF----GSFYL-RDVKRPVLMLAGGTGIAPFLSMLQ----VLEQKGSEHPV 241
Query: 596 VLFFGCRNRRMDFIYEEELQRFVESGALAE--LSVAFSREGPTKE-YVQHKMMDKASDIW 652
L FG D + E+L + E VA + ++ YV + +
Sbjct: 242 RLVFGVTQ-DCDLVALEQLDALQQKLPWFEYRTVVAHAESQHERKGYVTGHIE------Y 294
Query: 653 NMISQG-AYLYVCG 665
+ ++ G +Y+CG
Sbjct: 295 DWLNGGEVDVYLCG 308
>3OZU-A nrPDB
Length = 403
Score = 50.2 bits (118), Expect = 3e-06, Method: Composition-based stats.
Identities = 49/222 (22%), Positives = 79/222 (35%), Gaps = 27/222 (12%)
Query: 465 MAEFPSAKPPLGVFFAGVAPRLQPRFYSISSSPKIAETRIHVTCALVYEKMPTGRIHKGV 524
+ F + Q R YS+S P RI V ++ G G
Sbjct: 182 VVNFEPGQYTSVAIDVPALGLQQIRQYSLSDMPNGRSYRISV------KREGGGPQPPGY 235
Query: 525 CSTWMKNAVPYEKSENCSSAPIFVRQSNFKLPSDSKVPIIMIGPGTGLAPFRGFLQERLA 584
S + + V + +AP +F + D+K PI++I G GL P L ++A
Sbjct: 236 VSNLLHDHVNVG-DQVKLAAP----YGSFHIDVDAKTPIVLISGGVGLTPMVSML--KVA 288
Query: 585 LVESGVELGPSVLFFGCRNRRMDFIYEEELQRFVESGALAELSVAFSREGPTKEYVQHKM 644
L V G RN + + L+ ++ +L V + + P E VQ +
Sbjct: 289 LQAP---PRQVVFVHGARNSAV-HAMRDRLREAAKTYENLDLFVFY--DQPLPEDVQGRD 342
Query: 645 MDKASDI-WNMISQG-----AYLYVCGDA--KGMARDVHRSL 678
D + I + A Y+CG M D ++L
Sbjct: 343 YDYPGLVDVKQIEKSILLPDADYYICGPIPFMRMQHDALKNL 384
>5OGX-A nrPDB
Length = 336
Score = 49.8 bits (117), Expect = 4e-06, Method: Composition-based stats.
Identities = 44/232 (18%), Positives = 75/232 (32%), Gaps = 32/232 (13%)
Query: 411 ACLLSSPKKSALVALAAHASDPTEAERLKHLASPAGKDEYSKWVVESQRSLLEVMAEFPS 470
L + A + + A L+ L + + R +L +AE
Sbjct: 73 LALACQARPLADTEVRSTADAGRVTHPLRDLTATV---LEVADIARDTRRVLLGLAE--P 127
Query: 471 AKPPLGVFFAGVAPRLQPR-FYSISSSPKIAET-RIHVTCALVYEKMPTGRIHKGVCST- 527
G + V P R YS++++ + +HV R+ GV +
Sbjct: 128 LAFEAGQYVELVVPGSGARRQYSLANTADEDKVLELHVR-----------RVPGGVATDG 176
Query: 528 WMKNAVPYEKSENCSSAPIFVRQSNFKLP---SDSKVPIIMIGPGTGLAPFRGFLQERLA 584
W+ + + ++ P+ +F LP D P+++IG GTGLAP G +
Sbjct: 177 WLFDGLAAG-DRVEATGPL----GDFHLPPPDEDDGGPMVLIGGGTGLAPLVG-IARTAL 230
Query: 585 LVESGVELGPSVLFFGCRNRRMDFIYEEELQRFVESGALAELSVAFSREGPT 636
E+ +L+ G R D E S E
Sbjct: 231 ARHPSREV---LLYHGVRGA-ADLYDLGRFAEIAEEHPGFRFVPVLSDEPDP 278
>2FCR-A nrPDB
Length = 173
Score = 49.0 bits (115), Expect = 7e-06, Method: Composition-based stats.
Identities = 37/146 (25%), Positives = 60/146 (41%), Gaps = 15/146 (10%)
Query: 104 KVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYEEKLKKEDVAFF 163
K+ IFF T TG A +G+ A+ + DD + LK D+ F
Sbjct: 1 KIGIFFSTSTGNTTEVADFIGKTLGAKADAPI---------DVDDVTDPQALKDYDLLFL 51
Query: 164 FLATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQ-YE-HFNKVAKVVDD 221
T+ G T+ + + F +K+L +FGLG+ + Y +F + + D
Sbjct: 52 GAPTWNTGADTERSGTSWDEFLYDKLPEVDMKDLPVAIFGLGDAEGYPDNFCDAIEEIHD 111
Query: 222 ILVEQGAQRLVQVGLGD-DDQCIEDD 246
+QGA+ VG + DD E+
Sbjct: 112 CFAKQGAK---PVGFSNPDDYDYEES 134
>1CZN-A nrPDB
Length = 169
Score = 48.3 bits (113), Expect = 1e-05, Method: Composition-based stats.
Identities = 24/131 (18%), Positives = 51/131 (38%), Gaps = 16/131 (12%)
Query: 104 KVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYEEKLKKEDVAFF 163
K+ +F+GTQTG + A+++ +E I + D + +Y
Sbjct: 2 KIGLFYGTQTGVTQTIAESIQQEFGGESIVDLNDIANADASDLNAYDY---------LII 52
Query: 164 FLATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNR--QYEHFNKVAKVVDD 221
T+ GE + Y N +G+ + FG G++ ++F ++++
Sbjct: 53 GCPTWNVGELQSDWEGIYDDLDSVNFQGKKV-----AYFGAGDQVGYSDNFQDAMGILEE 107
Query: 222 ILVEQGAQRLV 232
+ G+Q +
Sbjct: 108 KISSLGSQTVG 118
>2V5U-A nrPDB
Length = 169
Score = 47.9 bits (112), Expect = 2e-05, Method: Composition-based stats.
Identities = 26/136 (19%), Positives = 58/136 (42%), Gaps = 25/136 (18%)
Query: 103 KKVTIFFGTQTGTAEGFAKALGEEA----KARYEKTRFKIVDLDDYAADDDEYEEKLKKE 158
KK+ +F+GTQTG E A+ + +E ++ ++ ++ DL+DY
Sbjct: 2 KKIGLFYGTQTGKTESVAEIIRDEFGNDVVTLHDVSQAEVTDLNDYQY------------ 49
Query: 159 DVAFFFLATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQ-Y-EHFNKVA 216
T+ GE + Y + + G+ + FG G++ Y ++F
Sbjct: 50 --LIIGCPTWNIGELQSDWEGLYSELDDVDFNGKLV-----AYFGTGDQAGYADNFQDAI 102
Query: 217 KVVDDILVEQGAQRLV 232
++++ + ++G + +
Sbjct: 103 GILEEKISQRGGKTVG 118
>4EH1-A nrPDB
Length = 243
Score = 47.5 bits (111), Expect = 2e-05, Method: Composition-based stats.
Identities = 39/190 (20%), Positives = 76/190 (40%), Gaps = 23/190 (12%)
Query: 489 RFYSISSSPKIAETRIHVTCALVYEKMPTGRIHKGVCSTWMKNAVPYEKSENCSSAPIFV 548
R YS+S + E RI V ++ G + G+ S ++ N V S ++
Sbjct: 55 RQYSLSHASNGREYRISV------KREGVGSDNPGLVSHYLHNNVKVG-----DSVKLYA 103
Query: 549 RQSNFKLPSDSKVPIIMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDF 608
+F + P+++I G G P + L +SGV + C + +
Sbjct: 104 PAGDFFYVERER-PVVLISAGVGATPMQAILHTLAKQNKSGVTY-----LYACNSAKEHT 157
Query: 609 IYEEELQRFVESGALAELSVAFSREGPTKEYVQHKMMDKASDIWNMISQGAYLYVCGDAK 668
+E Q + G + ++ + R+ + +Q +M + +++ I G + Y+CG
Sbjct: 158 FAQETAQLIAQQGWMQQV---WYRDESADDVLQGEM--QLAELILPIEDGDF-YLCGPIG 211
Query: 669 GMARDVHRSL 678
M V + L
Sbjct: 212 FMQYVVKQLL 221
>2WC1-A nrPDB
Length = 182
Score = 44.8 bits (104), Expect = 1e-04, Method: Composition-based stats.
Identities = 30/158 (18%), Positives = 56/158 (35%), Gaps = 27/158 (17%)
Query: 104 KVTIFFGTQTGTAEGFAKALGEEA--KARYEKTRFKIVDLDDYAADDDEYEEKLKKEDVA 161
K+ +FFG+ TGT AK + + + + D+ D+ A D
Sbjct: 3 KIGLFFGSDTGTTRKIAKQIKDMFDDEVMAKPLNVNRADVADFMAY-----------DFL 51
Query: 162 FFFLATYGDGEPTD-----NAARFYKWFTEGNDRGEWLKNLKYGVFGLGNR-QYE-HFNK 214
T GDG+ + + ++ D+ +FGLG++ Y F
Sbjct: 52 ILGTPTLGDGQLPGLSANAASESWEEFLPRIADQ--DFSGKTIALFGLGDQVTYPLEFVN 109
Query: 215 VAKVVDDILVEQGAQRLVQ-----VGLGDDDQCIEDDF 247
+ + ++GA + + G D +E +F
Sbjct: 110 ALFFLHEFFSDRGANVVGRWPAKGYGFEDSLAVVEGEF 147
>3W2G-A nrPDB
Length = 271
Score = 44.4 bits (103), Expect = 2e-04, Method: Composition-based stats.
Identities = 37/198 (18%), Positives = 61/198 (30%), Gaps = 23/198 (11%)
Query: 471 AKPPLGVFFAGVA---PRLQPRFYSISSSPKIAETRIHVTCALVYEKMPTGRIHKGV-CS 526
P+G A L R Y+ SS + VY K + G S
Sbjct: 41 LGLPVGQHIYLSARIDGNLVIRPYTPVSSDD--DKGFVDLVIKVYFKDTHPKFPAGGKMS 98
Query: 527 TWMKNAVPYEKSENCSSAPIFVRQSNFKL---PSDSKVPII-------MIGPGTGLAPFR 576
++++ + E + V Q K P P+I MI GTG+ P
Sbjct: 99 QYLESMKIGDTIEFRGPNGLLVYQGKGKFAIRPDKKSSPVIKTVKSVGMIAGGTGITPML 158
Query: 577 GFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEEELQRFVES-GALAELSVAFSREGP 635
+ R + + +LF D + EL+ A +L R
Sbjct: 159 QVI--RAIMKDPDDHTVCHLLF--ANQTEKDILLRPELEELRNEHSARFKLWYTVDRAPE 214
Query: 636 TKEYVQHKMMDK--ASDI 651
+Y Q + ++ +
Sbjct: 215 AWDYSQGFVNEEMIRDHL 232
>1YOB-A nrPDB
Length = 179
Score = 44.4 bits (103), Expect = 2e-04, Method: Composition-based stats.
Identities = 33/184 (17%), Positives = 56/184 (30%), Gaps = 41/184 (22%)
Query: 104 KVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYEEKLKKEDVAFF 163
K+ +FFG+ TG AK++ + RF + D + E +
Sbjct: 2 KIGLFFGSNTGKTRKVAKSIKK---------RFDDETMSDALNVNRVSAEDFAQYQFLIL 52
Query: 164 FLATYGDGEPTD-----NAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQ---------- 208
T G+GE + ++ G +FGLG++
Sbjct: 53 GTPTLGEGELPGLSSDAENESWEEFL--PKIEGLDFSGKTVALFGLGDQVGYPENYLDAL 110
Query: 209 ---YEHFNKVAKVVDDILVEQG-----AQRLVQ---VGLGDDDQCI----EDDFTAWREA 253
Y F + G ++ +V VGL D ++ AW
Sbjct: 111 GELYSFFKDRGAKIVGSWSTDGYEFESSEAVVDGKFVGLALDLDNQSGKTDERVAAWLAQ 170
Query: 254 LWPE 257
+ PE
Sbjct: 171 IAPE 174
>1UMK-A nrPDB
Length = 275
Score = 44.0 bits (102), Expect = 2e-04, Method: Composition-based stats.
Identities = 38/198 (19%), Positives = 62/198 (31%), Gaps = 23/198 (11%)
Query: 471 AKPPLGVFFAGVA---PRLQPRFYSISSSPKIAETRIHVTCALVYEKMPTGRIHKGV-CS 526
P+G A L R Y+ SS + VY K + G S
Sbjct: 45 LGLPVGQHIYLSARIDGNLVVRPYTPISSDD--DKGFVDLVIKVYFKDTHPKFPAGGKMS 102
Query: 527 TWMKNAVPYEKSENCSSAPIFVRQSNFKL---PSDSKVPII-------MIGPGTGLAPFR 576
++++ + E + + V Q K P PII MI GTG+ P
Sbjct: 103 QYLESMQIGDTIEFRGPSGLLVYQGKGKFAIRPDKKSNPIIRTVKSVGMIAGGTGITPML 162
Query: 577 GFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEEELQRFVES-GALAELSVAFSREGP 635
+ R + + +LF D + EL+ A +L R
Sbjct: 163 QVI--RAIMKDPDDHTVCHLLF--ANQTEKDILLRPELEELRNKHSARFKLWYTLDRAPE 218
Query: 636 TKEYVQHKMMDK--ASDI 651
+Y Q + ++ +
Sbjct: 219 AWDYGQGFVNEEMIRDHL 236
>2R6H-A nrPDB
Length = 290
Score = 42.9 bits (99), Expect = 5e-04, Method: Composition-based stats.
Identities = 31/157 (19%), Positives = 62/157 (39%), Gaps = 20/157 (12%)
Query: 487 QPRFYSISSSPKIAETRIHVTCALVYEKMPTGRIHK-------GVCSTWMKNAVPYEKSE 539
R YS+++ P AE I + +K G+ S+++ + P +
Sbjct: 85 TVRAYSMANYP--AEGNIITLNVRIATPPFDRAANKWKAGIKPGISSSYIFSLKPG--DK 140
Query: 540 NCSSAPIFVRQSNFKLPSDSKVPIIMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFF 599
S P +F + D+ ++ IG G G+AP R + +++G ++ ++
Sbjct: 141 VMMSGP----YGDFHI-QDTDAEMLYIGGGAGMAPLRAQILHLFRTLKTGRKVS---YWY 192
Query: 600 GCRNRRMDFIYEEELQRFVESGALAELSVAFSREGPT 636
G R + + YEE+ + + +A S P
Sbjct: 193 GAR-SKNEIFYEEDFREIEREFPNFKFHIALSDPQPE 228
>5THX-A nrPDB
Length = 266
Score = 41.7 bits (96), Expect = 0.001, Method: Composition-based stats.
Identities = 32/182 (17%), Positives = 62/182 (34%), Gaps = 40/182 (21%)
Query: 467 EFPSAKPPLGVFFAGVAPRLQPRFYSISSSPKIAETRIHVTCALVYEKMPTGRIHK-GVC 525
F + + + A P + R YS++S+ E + V + T R+ V
Sbjct: 39 RFENGQFVMVGLMADGKPLM--RAYSVASAN--WEEHLEFFSIKVQDGPLTSRLQHLKVG 94
Query: 526 STWMKNAVPYEKSENCSSAPIFVRQSNFKLPSDSKVPIIMIGPGTGLAPFRGFLQERLAL 585
+ + P C + + ++ GTG+APF ++
Sbjct: 95 DEVLISKKPTGTLVACDL--------------NPGKHLYLLSTGTGIAPFLSITKD---- 136
Query: 586 VESGVELGPSVLFFGCRNRRMDFIYEEELQRFVESGALAELSVAFSREGPTKEYVQHKMM 645
E + +L G R Y+++L + F++E P EY+ +
Sbjct: 137 PEIYEQFEKIILVHGVR-------YKKDLAYYDR----------FTKELPEHEYLGDLVK 179
Query: 646 DK 647
+K
Sbjct: 180 EK 181
>4B4D-A nrPDB
Length = 262
Score = 41.7 bits (96), Expect = 0.001, Method: Composition-based stats.
Identities = 29/183 (15%), Positives = 64/183 (34%), Gaps = 29/183 (15%)
Query: 440 HLASPAGKDEYSK---WVVESQRSLL---EVMAEFPSAKPPLGVFFAGVAPRLQPRFYSI 493
H++S G + + W ++ S + F + + + P L R YSI
Sbjct: 3 HMSSAFGAETVLEVRHW-TDAYFSFTTTRDAGFRFENGQFVMIGLETETRPLL--RAYSI 59
Query: 494 SSSPKIAETRIHVTCALVYEKMPTGRIHKGVCSTWMKNAVPYEKSENCSSAPIFVRQSNF 553
+S+ + + + ++ G ++ +++ P + +
Sbjct: 60 ASANWEE-----------HLEFFSIKVPDGPLTSRLQHIQP----GDKVLVGKKPTGTLL 104
Query: 554 KLPSDSKVPIIMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEEE 613
+ ++G GTGLAP+ +++ E+ +L G R D Y +
Sbjct: 105 ISDLHPGRNLYLLGTGTGLAPWLSIIKD----PETYERFDKVILTQGVR-FVQDLAYRDY 159
Query: 614 LQR 616
+R
Sbjct: 160 FER 162
>1AG9-A nrPDB
Length = 175
Score = 41.3 bits (95), Expect = 0.001, Method: Composition-based stats.
Identities = 36/149 (24%), Positives = 61/149 (40%), Gaps = 28/149 (18%)
Query: 106 TIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYEEKLKKEDVAFFFL 165
IFFG+ TG E AK + ++ + D+ D A +E L+ D+ +
Sbjct: 4 GIFFGSDTGNTENIAKMIQKQL-------GKDVADVHDIA---KSSKEDLEAYDILLLGI 53
Query: 166 ATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNRQ-Y-EHFNKVAKVVDDIL 223
T+ GE + F+ E + G+ + +FG G+++ Y E+F + DI+
Sbjct: 54 PTWYYGEAQCDWDDFFPTLEEIDFNGKLV-----ALFGCGDQEDYAEYFCDALGTIRDII 108
Query: 224 VEQGAQRLV-----------QVGLGDDDQ 241
+GA + GL DDD
Sbjct: 109 EPRGATIVGHWPTAGYHFEASKGLADDDH 137
>2BMV-A nrPDB
Length = 164
Score = 40.6 bits (93), Expect = 0.003, Method: Composition-based stats.
Identities = 32/174 (18%), Positives = 57/174 (32%), Gaps = 40/174 (22%)
Query: 104 KVTIFFGTQTGTAEGFAKALGEEAKARYEKTRFKIVDLDDYAADDDEYEEKLKKEDVAFF 163
K+ IFFGT +G AE A+ + + ++VD+ +E+
Sbjct: 3 KIGIFFGTDSGNAEAIAEKISK------AIGNAEVVDVAK------ASKEQFNSFTKVIL 50
Query: 164 FLATYGDGEPTDNAARFYKWFTEGNDRGEWLKNLKYGVFGLGNR-QY-EHFNKV------ 215
T G G+ + F G N G+ GLG++ Y E F +
Sbjct: 51 VAPTAGAGDLQTDWEDFL-----GTLEASDFANKTIGLVGLGDQDTYSETFAEGIFHIYE 105
Query: 216 --------------AKVVDDILVEQGAQRLVQVGLGDDDQCIEDDFTA-WREAL 254
+ +G + + V D+ + D+ + W E +
Sbjct: 106 KAKAGKVVGQTSTDGYHFEASKAVEGGKFVGLVIDEDNQDDLTDERISKWVEQV 159
>1A8P-A nrPDB
Length = 258
Score = 37.5 bits (85), Expect = 0.020, Method: Composition-based stats.
Identities = 26/140 (18%), Positives = 48/140 (34%), Gaps = 21/140 (15%)
Query: 467 EFPSAKPPLGVFFAGVAPRLQPRFYSISSSPKIAETRIHVTCALVYEKMPTGRIHKGVCS 526
F + + + P + R YSI+S + + + ++ G +
Sbjct: 31 RFENGQFVMIGLEVDGRPLM--RAYSIASPNYEE-----------HLEFFSIKVQNGPLT 77
Query: 527 TWMKNAVPYEKSENCSSAPIFVRQSNFKLPSDSKVPIIMIGPGTGLAPFRGFLQERLALV 586
+ +++ + S P ++ LP + M+ GTGLAPF +Q+
Sbjct: 78 SRLQH-LKEGDELMVSRKPTGTLVTSDLLPGKH---LYMLSTGTGLAPFMSLIQD----P 129
Query: 587 ESGVELGPSVLFFGCRNRRM 606
E VL G R
Sbjct: 130 EVYERFEKVVLIHGVRQVNE 149
>4G1B-A nrPDB
Length = 399
Score = 37.5 bits (85), Expect = 0.020, Method: Composition-based stats.
Identities = 37/184 (20%), Positives = 67/184 (36%), Gaps = 20/184 (10%)
Query: 489 RFYSISSSPKIAETRIHVTCALVYEKMPTGRIHKGVCSTWMKNAVPYEKSENCSSAPIFV 548
R YS+ S+ R V E P G+ S ++ E SAP
Sbjct: 207 RHYSLCSASTKNGLRFAVKMEAARENFPA-----GLVSEYLHKDAKVG-DEIKLSAPAGD 260
Query: 549 RQSNFKLPSDSKVPIIMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDF 608
N +L ++VP++++ G G+ P L+E+ V+ P+ + ++
Sbjct: 261 FAINKELIHQNEVPLVLLSSGVGVTPLLAMLEEQ-------VKCNPNRPIYWIQSS---- 309
Query: 609 IYEEELQRFVESGALAELSVAFSREGPTKEYVQHKMMDKASDIWNMISQGAYLYVCGDAK 668
Y+E+ Q F + EL + + + + A+ + A +Y CG
Sbjct: 310 -YDEKTQAFKKHVD--ELLAECANVDKIIVHTDTEPLINAAFLKEKSPAHADVYTCGSLA 366
Query: 669 GMAR 672
M
Sbjct: 367 FMQA 370
>6O0A-A nrPDB
Length = 413
Score = 37.5 bits (85), Expect = 0.023, Method: Composition-based stats.
Identities = 19/123 (15%), Positives = 35/123 (28%), Gaps = 23/123 (18%)
Query: 555 LPSDSKVPIIMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEEEL 614
L +D P+++I G G+ P F+++ A V+ + EL
Sbjct: 273 LETDPNSPLVLICAGIGVTPVLAFVEKLAAQKSE-----REVMIIASSRSLAEAPLRGEL 327
Query: 615 QRFVESGALAELSVAFSREGPTKEYVQHKMMDKASDIWNM------ISQGAYLYVCGDAK 668
+ K + + I A +++CG K
Sbjct: 328 LERAKE------------LKKAKVLYGTTQEKDGDFVGRIDVSTLDIPANASVFLCGPLK 375
Query: 669 GMA 671
M
Sbjct: 376 FMQ 378
>4U9U-A nrPDB
Length = 281
Score = 36.7 bits (83), Expect = 0.032, Method: Composition-based stats.
Identities = 23/114 (20%), Positives = 43/114 (37%), Gaps = 11/114 (9%)
Query: 558 DSKVPIIMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEEELQRF 617
D+ ++ IG G G+AP R + ++L ++S ++G R++R F Y E+
Sbjct: 144 DTDAEMVFIGGGAGMAPMRSHIFDQLKRLKSKR---KMSYWYGARSKREMF-YVEDFDGL 199
Query: 618 VESGALAELSVAFSREGPTKE------YVQHKMMDKASDIWNMISQGAYLYVCG 665
A S P ++ + + + Y Y+CG
Sbjct: 200 AAENDNFVWHCALSDPQPEDNWTGYTGFIHNVLYENYLKDHEAPEDCEY-YMCG 252
>4P6V-F nrPDB
Length = 408
Score = 36.7 bits (83), Expect = 0.032, Method: Composition-based stats.
Identities = 23/114 (20%), Positives = 43/114 (37%), Gaps = 11/114 (9%)
Query: 558 DSKVPIIMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEEELQRF 617
D+ ++ IG G G+AP R + ++L ++S ++G R++R F Y E+
Sbjct: 271 DTDAEMVFIGGGAGMAPMRSHIFDQLKRLKSKR---KMSYWYGARSKREMF-YVEDFDGL 326
Query: 618 VESGALAELSVAFSREGPTKE------YVQHKMMDKASDIWNMISQGAYLYVCG 665
A S P ++ + + + Y Y+CG
Sbjct: 327 AAENDNFVWHCALSDPQPEDNWTGYTGFIHNVLYENYLKDHEAPEDCEY-YMCG 379
>4WQM-A nrPDB
Length = 326
Score = 36.3 bits (82), Expect = 0.042, Method: Composition-based stats.
Identities = 45/244 (18%), Positives = 81/244 (33%), Gaps = 38/244 (15%)
Query: 443 SPAGKDEYSKWVVESQRSLLEVMA-EFPSAKP----PLGVFFAGVAPRLQPRFYSISSSP 497
+ +S VV + E+ + + P F P L R YS ++
Sbjct: 96 ASHPPKRFSTRVVSKRFLSDEMFELRLEAEQKVVFSPGQYFMVD-VPELGTRAYSAANPV 154
Query: 498 KIAETRIHVTCALVYEKMPTGRIHKGVCSTWMKNAVPYEKSENCSSAPIFVRQSNFKLPS 557
T L+ + +P G++ + + ++ L +
Sbjct: 155 DGN------TLTLIVKAVPNGKVSCALANETIETLQLDGPYGLSV------------LKT 196
Query: 558 DSKVPIIMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEEELQRF 617
+ + I G+G+AP + +A G E P +F+G R + E L +
Sbjct: 197 ADETQSVFIAGGSGIAPMVSMVNTLIA---QGYE-KPITVFYGSR-LEAELEAAETLFGW 251
Query: 618 VESGALAELS---VAFSREGPTKEYVQHKMMDKASDIWNMISQGAYLYVCGDAKGMARDV 674
E+ L +S V S YV + + + GA Y+CG + M V
Sbjct: 252 KENLKLINVSSSVVGNSESSYPTGYVHEIIPEYMEGLL-----GAEFYLCGPPQ-MINSV 305
Query: 675 HRSL 678
+ L
Sbjct: 306 QKLL 309
>2PIA-A nrPDB
Length = 321
Score = 36.0 bits (81), Expect = 0.054, Method: Composition-based stats.
Identities = 35/246 (14%), Positives = 75/246 (30%), Gaps = 46/246 (18%)
Query: 430 SDPTEAERLKHLASPAGKDEYSKWVVESQRSLLEVMAEFPSAKPPLGVFFAGVAPRLQPR 489
+ P E L+ + K W E + F G P R
Sbjct: 1 TTPQEDGFLRLKIASKEKIARDIWSFELTDPQGAPLPPF-----EAGANLTVAVPNGSRR 55
Query: 490 FYSISSSPKIAETRIHVTCALVYEKMPTGRIHKGVCSTWMKNAVPYEKSENCSSAPIFVR 549
YS+ + + + + ++ GR G +++ + SE + + +
Sbjct: 56 TYSLCNDSQERNRYV-----IAVKRDSNGR---GGSISFIDD-----TSEGDA-VEVSLP 101
Query: 550 QSNFKLPSDSKVPIIMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDFI 609
++ F L +K I++ G G+ P ++ A G R+ R+ ++
Sbjct: 102 RNEFPLDKRAKS-FILVAGGIGITPMLSMARQLRAE--------------GLRSFRLYYL 146
Query: 610 YEEE-----LQRFVESGALAELSVAFSREGPTKEYVQHKMMDKASDIWNMISQGAYLYVC 664
+ +++ + PTK + ++ ++Y C
Sbjct: 147 TRDPEGTAFFDELTSDEWRSDVKIHHDHGDPTKAF-------DFWSVFEKSKPAQHVYCC 199
Query: 665 GDAKGM 670
G M
Sbjct: 200 GPQALM 205
>2VNH-A nrPDB
Length = 272
Score = 35.2 bits (79), Expect = 0.091, Method: Composition-based stats.
Identities = 28/151 (18%), Positives = 53/151 (35%), Gaps = 24/151 (15%)
Query: 489 RFYSISSSPKIAETRIHVTCALVYEKMPTGRIHKGVCSTWMKNAVPYEKSENCSSAPIFV 548
R YSI+S E + ++ G ++ +++ E+ P+
Sbjct: 64 RAYSIASPAWDEELEFYSI-----------KVPDGPLTSRLQHIKVGEQIILRPK-PVGT 111
Query: 549 RQSNFKLPSDSKVPIIMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDF 608
+ LP + + GTG+APF ++E E+ + ++ CR
Sbjct: 112 LVIDALLPGKR---LWFLATGTGIAPFASLMRE----PEAYEKFDEVIMMHACRTVAELE 164
Query: 609 IYEEELQRFVESGALAELSVAFSREGPTKEY 639
+ ++ E + EL EG K Y
Sbjct: 165 YGRQLVEALQEDPLIGELV-----EGKLKYY 190
>3FPK-A nrPDB
Length = 251
Score = 33.6 bits (75), Expect = 0.27, Method: Composition-based stats.
Identities = 36/172 (20%), Positives = 65/172 (37%), Gaps = 25/172 (14%)
Query: 520 IHKGVCSTWMKNAVPYEKSENCSSAPIFVRQSNFKLPSDSKVPII-MIGPGTGLAPFRGF 578
+ +G S + P ++ + S A F F L + M+ GT + P+
Sbjct: 73 VPQGKLSPRLAALKPGDEVQVVSDASGF-----FVLDEVPDCETLWMLATGTAIGPYLSI 127
Query: 579 LQERLALVESGVELGPSVLFFGCRNRRMDFIY---EEELQRFVESGALAELSVAFSRE-- 633
LQ V +++ D Y ELQ+ E G L + SRE
Sbjct: 128 LQ-----YGQDVARFKNLVLVHAARFAADLSYLPLMLELQQRYE-GKL-RIQTVVSRENV 180
Query: 634 -----GPTKEYVQHKMMDKASDIWNMISQGAYLYVCGDAKGMARDVHRSLHT 680
G +++ ++KA + M + +++ +CG+ + M RD + L
Sbjct: 181 PGSLTGRVPALIENGELEKAVGL-PMDKETSHVMLCGNPQ-MVRDTQQLLKE 230
>1TLB-A nrPDB
Length = 326
Score = 33.6 bits (75), Expect = 0.31, Method: Composition-based stats.
Identities = 35/214 (16%), Positives = 64/214 (29%), Gaps = 48/214 (22%)
Query: 529 MKNAVPYEKSENCSSAPIFVRQSNFKLPSDSKV--PI------------IMIGPGTGLAP 574
+ +V Y + + + + N +LP D K P+ ++I P AP
Sbjct: 67 VNVSVVYGQLSPAAVSAMKADHKNLRLPEDPKTGLPVTDGVKFFACGLSMVIHPVNPHAP 126
Query: 575 FRGFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEEE---LQRFVESGALAELSVAFS 631
+ F G + ++YEE+ + + + +
Sbjct: 127 TTHLNYRYFETWNQDGTP-QTWWFGGGADLTPSYLYEEDGQLFHQLHKDALDKHDTALYP 185
Query: 632 REGP---TKEYVQHKM--------------MDKASDIWNMISQGAYLYVCGDAKGMARDV 674
R Y+ H+ +I M+ C DA
Sbjct: 186 RFKKWCDEYFYITHRKETRGIGGIFFDDYDERDPQEILKMVED------CFDA------F 233
Query: 675 HRSLHTIAQEQGSMDSTKAEGFVKNLQTSGRYLR 708
S TI + + M TK E + ++ GRY+
Sbjct: 234 LPSYLTIVKRRKDMPYTKEEQQWQAIR-RGRYVE 266
>2QDX-A nrPDB
Length = 257
Score = 32.9 bits (73), Expect = 0.46, Method: Composition-based stats.
Identities = 23/136 (16%), Positives = 48/136 (35%), Gaps = 21/136 (15%)
Query: 467 EFPSAKPPLGVFFAGVAPRLQPRFYSISSSPKIAETRIHVTCALVYEKMPTGRIHKGVCS 526
F + + + P + R YSI+S + + + ++ G +
Sbjct: 30 RFKTGQFVMIGLEVDGRPLM--RAYSIASPNYEE-----------HLEFFSIKVPDGPLT 76
Query: 527 TWMKNAVPYEKSENCSSAPIFVRQSNFKLPSDSKVPIIMIGPGTGLAPFRGFLQERLALV 586
+ +++ + S P + LP + ++ GTG+APF +Q+
Sbjct: 77 SRLQH-LKEGDELMVSRKPTGTLVHDDLLPGKH---LYLLSTGTGMAPFLSVIQD----P 128
Query: 587 ESGVELGPSVLFFGCR 602
E+ +L G R
Sbjct: 129 ETYERYEKVILVHGVR 144
>1FDR-A nrPDB
Length = 248
Score = 32.9 bits (73), Expect = 0.47, Method: Composition-based stats.
Identities = 34/202 (16%), Positives = 69/202 (34%), Gaps = 34/202 (16%)
Query: 489 RFYSISSSPKIAETRIHVTCALVYEKMPTGRIHKGVCSTWMKNAVPYEKSENCSSAPIFV 548
R YS +SP + ++ G S + P ++ + S A F
Sbjct: 50 RAYSYVNSPDNPDLEFYLVTV-----------PDGKLSPRLAALKPGDEVQVVSEAAGF- 97
Query: 549 RQSNFKLPSDSKVPII-MIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMD 607
F L + M+ GT + P+ L+ + ++ +++ D
Sbjct: 98 ----FVLDEVPHCETLWMLATGTAIGPYLSILR-----LGKDLDRFKNLVLVHAARYAAD 148
Query: 608 FIYEEELQRFVE--SGALAELSVAFSRE-------GPTKEYVQHKMMDKASDIWNMISQG 658
Y +Q + G L + SRE G ++ ++ + M +
Sbjct: 149 LSYLPLMQELEKRYEGKL-RIQTVVSRETAAGSLTGRIPALIESGELESTIGL-PMNKET 206
Query: 659 AYLYVCGDAKGMARDVHRSLHT 680
+++ +CG+ + M RD + L
Sbjct: 207 SHVMLCGNPQ-MVRDTQQLLKE 227
>1TK1-A nrPDB
Length = 260
Score = 31.7 bits (70), Expect = 1.2, Method: Composition-based stats.
Identities = 19/105 (18%), Positives = 35/105 (33%), Gaps = 15/105 (14%)
Query: 529 MKNAVPYEKSENCSSAPIFVRQSNFKLPSDSKV--PI------------IMIGPGTGLAP 574
+ +V Y + + + + N +LP D K P+ ++I P AP
Sbjct: 64 VNVSVVYGQLSPAAVSAMKADHKNLRLPEDPKTGLPVTDGVKFFACGLSMVIHPVNPHAP 123
Query: 575 FRGFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEEELQRFVE 619
+ F G + ++YEE+ Q F +
Sbjct: 124 TTHLNYRYFETWNQDGTP-QTWWFGGGADLTPSYLYEEDGQLFHQ 167
>1GVH-A nrPDB
Length = 396
Score = 31.7 bits (70), Expect = 1.2, Method: Composition-based stats.
Identities = 38/215 (17%), Positives = 65/215 (30%), Gaps = 31/215 (14%)
Query: 464 VMAEFPSAKPPLGVFFAGVAPRLQPRFYSISSSPKIAETRIHVTCALVYEKMPTGRIHKG 523
+AE+ + P + R YS++ P RI V K G G
Sbjct: 179 AVAEYRPGQYLGVWLKPEGFPHQEIRQYSLTRKPDGKGYRIAV-------KREEG----G 227
Query: 524 VCSTWMKNAVPYEKSENCSSAPIFVRQSNFKLPSDSKVPIIMIGPGTGLAPFRGFLQERL 583
S W+ N AP +F + P+ +I G G P L
Sbjct: 228 QVSNWLHNHANVG-DVVKLVAPA----GDFFMAVADDTPVTLISAGVGQTPMLAMLDTLA 282
Query: 584 ALVESGVELGPSVLFFGCRNRRMDFIYEEELQRFVESGALAELSVAFSREGPTKEYVQHK 643
+ + F N + + +E++ G A + E + K
Sbjct: 283 KAGHTAQV---NW-FHAAENGDV-HAFADEVKEL---GQSLPRFTAHTWYRQPSEADRAK 334
Query: 644 MMDKASDIWNMIS-QGAY------LYVCGDAKGMA 671
+ + ++ +GA+ Y+CG M
Sbjct: 335 GQFDSEGLMDLSKLEGAFSDPTMQFYLCGPVGFMQ 369
>5MWL-A nrPDB
Length = 471
Score = 31.3 bits (69), Expect = 1.4, Method: Composition-based stats.
Identities = 19/147 (12%), Positives = 42/147 (28%), Gaps = 15/147 (10%)
Query: 530 KNAVPYEKSENCSSAPIFVRQSNFKLPSDSKVPIIMIGPGTGLAPFRGFLQERLALVESG 589
+ S P R F + + I P G PF + +
Sbjct: 104 CDKDLDTFSGYAMCLPNLTRLQTFHFAEHRPILCVEIKPKCGFIPFSNDVTHEMKHKV-- 161
Query: 590 VELGPSVLFFGCRNRRMDFIYEEELQRFVESGALAELSVAFSREGPTKEYVQHKMMDKAS 649
CR + + ++ + L + + ++ + + +
Sbjct: 162 -----------CRYCMHQHL-KVATGKWKKISKYCPLDLYSGNKQRMHFALRSLLQETQN 209
Query: 650 DIWNMISQGAYLYVCGDAKGMARDVHR 676
++ + G +Y CGDA+ D+
Sbjct: 210 NL-RIFKNGELIYGCGDARSPVADLKE 235
>2EIX-A nrPDB
Length = 243
Score = 31.3 bits (69), Expect = 1.5, Method: Composition-based stats.
Identities = 16/64 (25%), Positives = 26/64 (40%), Gaps = 4/64 (6%)
Query: 565 MIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEEELQRFVESGALA 624
MI GTG+ P LQ A++++ E L F N D + EL + +
Sbjct: 121 MIAGGTGITP---MLQVARAIIKNPKEKTIINLIFANVNED-DILLRTELDDMAKKYSNF 176
Query: 625 ELSV 628
++
Sbjct: 177 KVYY 180
>6F4A-A nrPDB
Length = 832
Score = 31.3 bits (69), Expect = 1.5, Method: Composition-based stats.
Identities = 36/196 (18%), Positives = 66/196 (33%), Gaps = 17/196 (8%)
Query: 284 SIHDSEDAKFNDINMANGNGYTVFDAQHPYKANVAVKRELHTPESDRSCIHLEFDIAGSG 343
IHD F D + D + + ++ + + EF I +
Sbjct: 563 RIHDDNAVVFGDGFNKGLVSLSPDDD-----GELCIPTFYDQSQTKSTLLVSEFMILTNK 617
Query: 344 LT---YETGDHVGVL-CDNLSETVDEA---LRLL--DMSPDTYFSLHAEKEDGTPISSSL 394
L ++ GV C N ++A LL ++ SL + + +SSS
Sbjct: 618 LCAAFFQENKIPGVYRCYNGLNLGNQAKAQFELLKENIKLGKLPSLKDITKISSQLSSSF 677
Query: 395 PPPFPPCNLRTALTRYACLLSSPKKSALVALAAHASDPTEAERLKHLASPAGKDEYSKWV 454
PFP + T Y + S ++ L H ++L D+Y W
Sbjct: 678 YSPFPLPHKMIGNTAYLTVTSPMRRGP--DLINHLQLHRFLKKLPLCFKQEYLDQY-VWS 734
Query: 455 VESQRSLLEVMAEFPS 470
+++ +L++ S
Sbjct: 735 FQARADILKIFQRHSS 750
>5UFA-A nrPDB
Length = 267
Score = 31.3 bits (69), Expect = 1.6, Method: Composition-based stats.
Identities = 36/259 (13%), Positives = 86/259 (33%), Gaps = 44/259 (16%)
Query: 445 AGKDEYSKWVVESQRSLLEVMAEFPSAKPPLGVFFAGVAPRLQP--------RFYSISSS 496
+ + ++++ + + + F ++P F AG RL R YS+ S+
Sbjct: 12 SPEAKFTEEKILWVKHHTPKLITFAISRPESYRFKAGQFSRLGFYEGKGFIWRAYSVVSA 71
Query: 497 PKIAETRIHVTCALVYEKMPTGRIHKGVCSTWMKNAVPYEKSENCSSAPIFVRQSNFKLP 556
+ L+ G + + + +K+ P + P
Sbjct: 72 --EYADTLEYFAVLI----QDGPMSALFAKMQQGDTILLDKNATGFLLPE-------RFP 118
Query: 557 SDSKVPIIMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEEELQR 616
++M+ G+G+APF L++ +V + + I+ + L
Sbjct: 119 DGKD--LVMLCTGSGIAPFLSILEQPEIRQRFD-----TVNLIHSVSFPEELIFNDRLAA 171
Query: 617 FVESGALAELSVAF------SREGPTK----EYVQHKMM----DKASDIWNMISQGAYLY 662
E + E +F +R + + + ++A + +
Sbjct: 172 LSEHPLVGEYGHSFRFVPVTTRAANPSGLSGKRIPELLKNNSIEQALHT-KLTPESTRFM 230
Query: 663 VCGDAKGMARDVHRSLHTI 681
+CG+ + M +D ++L +
Sbjct: 231 ICGNPE-MVKDTFQTLLDM 248
>4FK8-A nrPDB
Length = 271
Score = 30.9 bits (68), Expect = 2.0, Method: Composition-based stats.
Identities = 17/93 (18%), Positives = 35/93 (37%), Gaps = 15/93 (16%)
Query: 489 RFYSISSSPKIAETRIHVTCALVYEKMPTGRIHKGVCSTWMKNAVPYEKSENCSSAPIFV 548
R YSI S + + + ++ G ++ +++ + P
Sbjct: 66 RAYSIVSPNYEE-----------HLEFFSIKVQNGPLTSRLQH-LKVGDPVLIGKKPTGT 113
Query: 549 RQSNFKLPSDSKVPIIMIGPGTGLAPFRGFLQE 581
++ LP + M+ GTGLAPF +++
Sbjct: 114 LVADNLLPGK---TLWMLSTGTGLAPFMSIIRD 143
>2RCQ-A nrPDB
Length = 141
Score = 30.6 bits (67), Expect = 2.3, Method: Composition-based stats.
Identities = 17/68 (25%), Positives = 25/68 (36%), Gaps = 5/68 (7%)
Query: 602 RNRRMDFIYEEELQRFVESGALAELSVAFSREGPTKEYVQHKMMDKASDIWNMISQGAYL 661
RN +DF E + +S + + EG VQ + W +G L
Sbjct: 62 RNYDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLVCVQKGEKENRG--WKQWIEGDKL 119
Query: 662 YV---CGD 666
Y+ CGD
Sbjct: 120 YLELTCGD 127
>5J5Z-A nrPDB
Length = 496
Score = 30.6 bits (67), Expect = 2.3, Method: Composition-based stats.
Identities = 33/153 (21%), Positives = 57/153 (37%), Gaps = 17/153 (11%)
Query: 556 PSDSKVPIIMIGPGTGLAPFRGF-LQERLALVESGVELGPSVLFFGCRNRRMDFIYEEEL 614
P D+ V +I GPG +A + L + +E LG + L GC + +
Sbjct: 26 PIDADVTVIGSGPGGYVAAIKAAQLGFKTVCIEKNETLGGTCLNVGCIPSKA-LLNNSHY 84
Query: 615 QRFVESGALAELSVAFSR--EGPTKEYVQHKMMDKASDIWNMISQG-AYLYVCGDAKGMA 671
A SR E KMM++ S ++ G A+L+
Sbjct: 85 YHMAHGKDFA------SRGIEMSEVRLNLDKMMEQKSTAVKALTGGIAHLF------KQN 132
Query: 672 RDVHRSLHTIAQEQGSMDSTKAEGFVKNLQTSG 704
+ VH + + + + +TKA+G + + T
Sbjct: 133 KVVHVNGYGKITGKNQVTATKADGGTQVIDTKN 165
>6D35-A nrPDB
Length = 600
Score = 30.2 bits (66), Expect = 3.4, Method: Composition-based stats.
Identities = 16/66 (24%), Positives = 28/66 (42%), Gaps = 3/66 (4%)
Query: 591 ELGPSVLFFGCRNRRMDFIYEEELQRFVESGALAELSVAFSREGPTKEYVQHKMMDKASD 650
G ++ FGC DF + E +R L E +VA + E K + + ++ S
Sbjct: 504 AFGFVLITFGCHFY--DFFNQAEWERSFREYVLCEANVAIA-EQTNKPIPECYIKNRPSL 560
Query: 651 IWNMIS 656
+ I+
Sbjct: 561 LVEKIN 566
>1EII-A nrPDB
Length = 134
Score = 29.8 bits (65), Expect = 4.7, Method: Composition-based stats.
Identities = 17/68 (25%), Positives = 24/68 (35%), Gaps = 5/68 (7%)
Query: 602 RNRRMDFIYEEELQRFVESGALAELSVAFSREGPTKEYVQHKMMDKASDIWNMISQGAYL 661
RN +DF E + + + EG T VQ + W +G L
Sbjct: 59 RNYDLDFTVGVEFDEHTKGLDGRNVKTLVTWEGNTLVCVQKGEKENRG--WKQWVEGDKL 116
Query: 662 YV---CGD 666
Y+ CGD
Sbjct: 117 YLELTCGD 124
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
Posted date: Jan 3, 2023 9:05 PM
Number of letters in database: 10,336,785
Number of sequences in database: 36,641
Lambda K H
0.307 0.121 0.303
Lambda K H
0.267 0.0377 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,424,523
Number of Sequences: 36641
Number of extensions: 896092
Number of successful extensions: 2838
Number of sequences better than 10.0: 69
Number of HSP's better than 10.0 without gapping: 55
Number of HSP's successfully gapped in prelim test: 64
Number of HSP's that attempted gapping in prelim test: 2592
Number of HSP's gapped (non-prelim): 132
length of query: 711
length of database: 10,336,785
effective HSP length: 104
effective length of query: 607
effective length of database: 6,526,121
effective search space: 3961355447
effective search space used: 3961355447
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.2 bits)
S2: 62 (28.6 bits)