BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9SU91 (336 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3T57-A nrPDB 632 0.0 4E6U-A nrPDB 219 1e-57 4EQY-A nrPDB 188 2e-48 5JXX-A nrPDB 181 4e-46 2JF2-A nrPDB 180 7e-46 5DEP-A nrPDB 176 9e-45 4R36-A nrPDB 164 4e-41 1J2Z-A nrPDB 156 9e-39 5F42-A nrPDB 156 2e-38 3R0S-A nrPDB 153 1e-37 3I3A-A nrPDB 149 1e-36 4IHG-A nrPDB 71 6e-13 4E79-A nrPDB 58 7e-09 3PMO-A nrPDB 57 1e-08 2IUA-A nrPDB 50 1e-06 4M9C-A nrPDB 46 2e-05 4MFG-A nrPDB 42 6e-04 1XHD-A nrPDB 40 0.001 3NZ2-A nrPDB 40 0.002 4G3P-A nrPDB 40 0.002 3MQG-A nrPDB 39 0.003 1OCX-A nrPDB 36 0.019 4H7O-A nrPDB 36 0.023 1KRR-A nrPDB 35 0.042 3TIO-A nrPDB 35 0.053 2P2O-A nrPDB 35 0.053 3IGJ-A nrPDB 35 0.058 1HM0-A nrPDB 35 0.058 6I7T-G nrPDB 34 0.084 6JLY-I nrPDB 34 0.11 4ISX-A nrPDB 33 0.12 2NPO-A nrPDB 33 0.13 4DCL-A nrPDB 32 0.26 4N6B-A nrPDB 32 0.29 3R8Y-A nrPDB 32 0.35 5VMK-A nrPDB 31 0.92 2QKX-A nrPDB 30 1.5 5K1Q-A nrPDB 30 2.0 2OI7-A nrPDB 29 2.9 2YWH-A nrPDB 29 3.0 1T3D-A nrPDB 29 3.1 3CJ8-A nrPDB 29 3.4 3GVD-A nrPDB 29 3.6 1SST-A nrPDB 29 3.7 1A59-A nrPDB 28 3.8 3TWD-A nrPDB 28 4.8 6O85-A nrPDB 28 5.0 6F3A-U nrPDB 27 8.7 >3T57-A nrPDB Length = 305 Score = 632 bits (1631), Expect = 0.0, Method: Compositional matrix adjust. Identities = 304/304 (100%), Positives = 304/304 (100%) Query: 33 DSRDSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGES 92 DSRDSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGES Sbjct: 2 DSRDSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGES 61 Query: 93 CVLMTGAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFC 152 CVLMTGAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFC Sbjct: 62 CVLMTGAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFC 121 Query: 153 SIHRSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGAS 212 SIHRSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGAS Sbjct: 122 SIHRSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGAS 181 Query: 213 VVHQFCHIGSFAFIGGGSVVSQDVPKYMMVAGERAELRGLNLEGLRRNGFTMSEMKSLRA 272 VVHQFCHIGSFAFIGGGSVVSQDVPKYMMVAGERAELRGLNLEGLRRNGFTMSEMKSLRA Sbjct: 182 VVHQFCHIGSFAFIGGGSVVSQDVPKYMMVAGERAELRGLNLEGLRRNGFTMSEMKSLRA 241 Query: 273 AYRKIFMSTETVSLSFEERLTELEQDQELYSVPAVSAMLQSIRDSFTESRRGICKFRQWL 332 AYRKIFMSTETVSLSFEERLTELEQDQELYSVPAVSAMLQSIRDSFTESRRGICKFRQWL Sbjct: 242 AYRKIFMSTETVSLSFEERLTELEQDQELYSVPAVSAMLQSIRDSFTESRRGICKFRQWL 301 Query: 333 DSTT 336 DSTT Sbjct: 302 DSTT 305 >4E6U-A nrPDB Length = 265 Score = 219 bits (558), Expect = 1e-57, Method: Compositional matrix adjust. Identities = 128/289 (44%), Positives = 174/289 (60%), Gaps = 33/289 (11%) Query: 40 LIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGA 99 LIH +A++ P+AVI V +GPYC IG V +G G KL+ SHV Sbjct: 9 LIHSTAIIDPSAVIASDVQIGPYCIIGPQVTIGAGTKLH--SHV---------------- 50 Query: 100 VVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSSK 159 VVG G+T IG NN I A VG CQDLKYK G+E +L IGNNN IRE CS+HR + Sbjct: 51 VVG----GFTRIGQNNEIFQFASVGEVCQDLKYK-GEETWLEIGNNNLIREHCSLHRGTV 105 Query: 160 PSDK-TVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFC 218 + T IG +NL+M + HIAHDC +GD NIFANN +AGHV + D+ G S +HQFC Sbjct: 106 QDNALTKIGSHNLLMVNTHIAHDCIVGDHNIFANNVGVAGHVHIGDHVIVGGNSGIHQFC 165 Query: 219 HIGSFAFIGGGSVVSQDVPKYMMVAGERAELRGLNLEGLRRNGFTMSEMKSLRAAYRKIF 278 I S++ IGG S++ +DVP Y+M +G A G+N+EG+RR G++ + ++ LR AY+ IF Sbjct: 166 KIDSYSMIGGASLILKDVPAYVMASGNPAHAFGINIEGMRRKGWSKNTIQGLREAYKLIF 225 Query: 279 MSTETVSLSFEERLTELEQDQELYSVPAVSAMLQSIRDSFTESRRGICK 327 S T + ++ +E+ L SVP ++ DS +S RGI + Sbjct: 226 KSGLTSVQAIDQIKSEI-----LPSVPEAQLLI----DSLEQSERGIVR 265 >4EQY-A nrPDB Length = 283 Score = 188 bits (478), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 108/291 (37%), Positives = 166/291 (57%), Gaps = 36/291 (12%) Query: 41 IHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAV 100 IHP+A++ P A + + V VGPY +GS+V +G T +G V+ Sbjct: 25 IHPTAIIEPGAQLHETVEVGPYAIVGSNVTIG------------ARTTIGSHSVI----- 67 Query: 101 VGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSS-K 159 G+T IG +N IGH+A VG + QD+KYK + L IG+ N IREF +IH + + Sbjct: 68 -----EGHTTIGEDNRIGHYASVGGRPQDMKYKD-EPTRLVIGDRNTIREFTTIHTGTVQ 121 Query: 160 PSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFCH 219 + T +GD+N IM HI HDC++G + ++N +AGHV + D G S VHQ+ Sbjct: 122 DAGVTTLGDDNWIMAYVHIGHDCRVGSHVVLSSNAQMAGHVEIGDWAIVGGMSGVHQYVR 181 Query: 220 IGSFAFIGGGSVVSQDVPKYMMVAGERAELRGLNLEGLRRNGFTMSEMKSLRAAYRKIFM 279 IG+ + +GG S + QD+P +++ AG +AE G+N+EGLRR GF+ + +LR+AYR ++ Sbjct: 182 IGAHSMLGGASALVQDIPPFVIAAGNKAEPHGINVEGLRRRGFSPDAISALRSAYRILYK 241 Query: 280 STETVSLSFEE---RLTELEQDQELYSVPAVSAMLQSIRDSFTESRRGICK 327 + SLS EE +L+EL Q + A ++++ D S+RGI + Sbjct: 242 N----SLSLEEAKVQLSELAQ-----AGGDGDAAVKALVDFVESSQRGIIR 283 >5JXX-A nrPDB Length = 257 Score = 181 bits (459), Expect = 4e-46, Method: Compositional matrix adjust. Identities = 105/288 (36%), Positives = 161/288 (55%), Gaps = 34/288 (11%) Query: 41 IHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAV 100 IHP+A++ +A+I +GPYC +G N+++G VL + + Sbjct: 3 IHPTAIIDKSAMIADSAIIGPYCIVGK------------------NSQIGAHTVLRSHVI 44 Query: 101 VGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSS-K 159 +G+ T IG +N I A +G QDLKY G++ +L IG++N IRE C+IHR + + Sbjct: 45 IGEN----TKIGVHNDIYQFASIGENPQDLKYA-GEQTYLEIGDHNRIREACTIHRGTVQ 99 Query: 160 PSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFCH 219 T IG+ NL+M + HIAHDC +GD N+ ANN +AGH + ++ G S VHQFC Sbjct: 100 DRGITRIGNQNLLMVNVHIAHDCVVGDDNVLANNVGVAGHAHIGNHVIIGGQSGVHQFCR 159 Query: 220 IGSFAFIGGGSVVSQDVPKYMMVAGERAELRGLNLEGLRRNGFTMSEMKSLRAAYRKIFM 279 I ++ +GG S++ +DV Y+M +G A+ GLN EG+RR G++ +K+L AYR +F Sbjct: 160 IDDYSMVGGASLIVKDVAAYVMASGNPAKAHGLNKEGMRRKGWSKDTIKALDEAYRLVFR 219 Query: 280 STETVSLSFEERLTELEQDQELYSVPAVSAMLQSIRDSFTESRRGICK 327 S L +E L EL + E P + ++ DS S+RG+ + Sbjct: 220 S----GLLRDEALDELTKLVE--KEPKIQLLI----DSINNSKRGLVR 257 >2JF2-A nrPDB Length = 264 Score = 180 bits (457), Expect = 7e-46, Method: Compositional matrix adjust. Identities = 112/293 (38%), Positives = 157/293 (53%), Gaps = 34/293 (11%) Query: 36 DSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVL 95 D +HP+A+V A IG +GP+C +G V++G G L SHV N Sbjct: 5 DKSAFVHPTAIVEEGASIGANAHIGPFCIVGPHVEIGEGTVL--KSHVVVN--------- 53 Query: 96 MTGAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIH 155 G+T IG +N I A +G QDLKY G+ + IG+ N IRE +IH Sbjct: 54 -----------GHTKIGRDNEIYQFASIGEVNQDLKYA-GEPTRVEIGDRNRIRESVTIH 101 Query: 156 RSS-KPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVV 214 R + + T +G +NL+M + HIAHDC +G+R I ANN LAGHV V+D G + V Sbjct: 102 RGTVQGGGLTKVGSDNLLMINAHIAHDCTVGNRCILANNATLAGHVSVDDFAIIGGMTAV 161 Query: 215 HQFCHIGSFAFIGGGSVVSQDVPKYMMVAGERAELRGLNLEGLRRNGFTMSEMKSLRAAY 274 HQFC IG+ +GG S V+QDVP Y++ G A G+N+EGL+R GF+ + ++R AY Sbjct: 162 HQFCIIGAHVMVGGCSGVAQDVPPYVIAQGNHATPFGVNIEGLKRRGFSREAITAIRNAY 221 Query: 275 RKIFMSTETVSLSFEERLTELEQDQELYSVPAVSAMLQSIRDSFTESRRGICK 327 + I+ S +T +E E+ + E Y P V A D F S RG+ + Sbjct: 222 KLIYRSGKT----LDEVKPEIAELAETY--PEVKAFT----DFFARSTRGLIR 264 Score = 28.1 bits (61), Expect = 5.2, Method: Compositional matrix adjust. Identities = 18/68 (26%), Positives = 30/68 (44%) Query: 154 IHRSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASV 213 I +S+ ++ + I + HI C +G T+L HVVV +T + Sbjct: 4 IDKSAFVHPTAIVEEGASIGANAHIGPFCIVGPHVEIGEGTVLKSHVVVNGHTKIGRDNE 63 Query: 214 VHQFCHIG 221 ++QF IG Sbjct: 64 IYQFASIG 71 >5DEP-A nrPDB Length = 258 Score = 176 bits (447), Expect = 9e-45, Method: Compositional matrix adjust. Identities = 110/289 (38%), Positives = 153/289 (52%), Gaps = 34/289 (11%) Query: 40 LIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGA 99 LI P A++ P+A + V VGP+ +G+ V++G G + P HV Sbjct: 3 LIDPRAIIDPSARLAADVQVGPWSIVGAEVEIGEGTVIGP--HVV--------------- 45 Query: 100 VVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSS- 158 L G T IG +N I + VG DLKYK G+ L IG++N IRE +IHR + Sbjct: 46 -----LKGPTKIGKHNRIYQFSSVGEDTPDLKYK-GEPTRLVIGDHNVIREGVTIHRGTV 99 Query: 159 KPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFC 218 + +T IGD+NLIM HI HD IG+ I NNT LAGHV V+D +G ++VHQ+C Sbjct: 100 QDRAETTIGDHNLIMAYAHIGHDSVIGNHCILVNNTALAGHVHVDDWAILSGYTLVHQYC 159 Query: 219 HIGSFAFIGGGSVVSQDVPKYMMVAGERAELRGLNLEGLRRNGFTMSEMKSLRAAYRKIF 278 IG+ +F G GS + +DVP Y+ V G AE R +N EG+RR GF+ + +LR AY+ ++ Sbjct: 160 RIGAHSFSGMGSAIGKDVPAYVTVFGNPAEARSMNFEGMRRRGFSSEAIHALRRAYKVVY 219 Query: 279 MSTETVSLSFEERLTELEQDQELYSVPAVSAMLQSIRDSFTESRRGICK 327 TV + E Q P V+ RDS + RGI + Sbjct: 220 RQGHTVEEALAELAESAAQ------FPEVAVF----RDSIQSATRGITR 258 >4R36-A nrPDB Length = 275 Score = 164 bits (416), Expect = 4e-41, Method: Compositional matrix adjust. Identities = 95/288 (32%), Positives = 157/288 (54%), Gaps = 33/288 (11%) Query: 40 LIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGA 99 +I P A +HP A IG+ V + P+ I +V +G+ K+ ++++ + +G + GA Sbjct: 21 MISPLAYIHPEAKIGENVEIAPFVYIDRNVVIGDNNKIMANANILYGSRIGNGNTIFPGA 80 Query: 100 VVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSSK 159 V+G +P QDLK+K G+E IG+NN IRE +I+R + Sbjct: 81 VIG-AIP---------------------QDLKFK-GEESTAEIGDNNLIRENVTINRGTA 117 Query: 160 PSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFCH 219 +T++G+NNL+M H+AHD IG+ I N+T +AG ++++DN + ++HQFC Sbjct: 118 AKGRTIVGNNNLLMEGVHVAHDALIGNGCIVGNSTKMAGEIIIDDNAIISANVLMHQFCR 177 Query: 220 IGSFAFIGGGSVVSQDVPKYMMVAGERAELRGLNLEGLRRNGFTMSEMKSLRAAYRKIFM 279 +G + I GG S+D+P Y++ E G+N+ GLRR GF+ ++++ AYR I+ Sbjct: 178 VGGYVMIQGGCRFSKDIPPYIIAGREPIAYSGINIIGLRRRGFSNEIIENIHNAYRIIYQ 237 Query: 280 STETVSLSFEERLTELEQDQELYSVPAVSAMLQSIRDSFTESRRGICK 327 S L+ + LT++E + VPA S ++ I D S RGI + Sbjct: 238 S----GLNTSDALTKVEAE-----VPA-SPEIEYIVDFIRNSERGIIR 275 >1J2Z-A nrPDB Length = 270 Score = 156 bits (395), Expect = 9e-39, Method: Compositional matrix adjust. Identities = 96/255 (37%), Positives = 132/255 (51%), Gaps = 29/255 (11%) Query: 41 IHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAV 100 I +A++ P A I KGV +G +C IG VKL G KL+ + Sbjct: 4 IAKTAIISPKAEINKGVEIGEFCVIGDGVKLDEGVKLHNNV------------------- 44 Query: 101 VGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSSKP 160 L G+TF+G N I AV+G + QDLKYK G+ L IG +N IREFC I+ ++ Sbjct: 45 ---TLQGHTFVGKNTEIFPFAVLGTQPQDLKYK-GEYSELIIGEDNLIREFCMINPGTEG 100 Query: 161 S-DKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFCH 219 KT+IGD NL+M H+AHDC IG I AN LAGH+ + D + G + +HQF Sbjct: 101 GIKKTLIGDKNLLMAYVHVAHDCVIGSHCILANGVTLAGHIEIGDYVNIGGLTAIHQFVR 160 Query: 220 IGSFAFIGGGSVVSQDVPKYMMVAGERAELRGLNLEGLRRNGFTMSEMKSLRAAYRKIFM 279 I I G S + +DVP Y V G RA +RGLN +R+ ++ + A Y+++F Sbjct: 161 IAKGCMIAGKSALGKDVPPYCTVEGNRAFIRGLNRHRMRQL-LESKDIDFIYALYKRLFR 219 Query: 280 ST----ETVSLSFEE 290 E+ L EE Sbjct: 220 PIPSLRESAKLELEE 234 >5F42-A nrPDB Length = 280 Score = 156 bits (394), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 103/291 (35%), Positives = 146/291 (50%), Gaps = 35/291 (12%) Query: 40 LIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGA 99 +IH AVVH +A I +GP+C IG +V +G NTEL + A Sbjct: 1 MIHSLAVVHESAKIADSAIIGPFCVIGKNVVIGE------------NTELKSHVTIGDNA 48 Query: 100 VVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHR-SS 158 V+G NN I +A +G D YK GD + IG+NN IRE +IH ++ Sbjct: 49 VIGK----------NNRIFQYASIGDDPIDYTYKKGDFSQVVIGDNNIIRECATIHGGTA 98 Query: 159 KPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFC 218 K T +G+NN+IM HI HDCKIG N LAGHV ++D + VHQFC Sbjct: 99 KEIGVTSVGNNNIIMCYVHIGHDCKIGSYINLVNGVGLAGHVHIDDYAILSSNVGVHQFC 158 Query: 219 HIGSFAFIGGGSVVSQDVPKYMMVAGERAELR--GLNLEGLRRNGFTMSEMKSLRAAYRK 276 +G AFI ++V +DVP Y+MV A G+N EGL+R GFT EMK ++ Y+ Sbjct: 159 RVGKHAFIAHAALVGKDVPPYLMVTAVNAGSTPCGINTEGLKRRGFTPEEMKKIKEVYKV 218 Query: 277 IFMSTETVSLSFEERLTELEQDQELYSVPAVSAMLQSIRDSFTESRRGICK 327 ++ + +F E + E+ ++ ++ L+ D SRRGI + Sbjct: 219 LYRKGLMMKEAF-EIIKEMAKEDKV---------LEPFVDVIGTSRRGILR 259 >3R0S-A nrPDB Length = 266 Score = 153 bits (386), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 95/290 (32%), Positives = 142/290 (48%), Gaps = 36/290 (12%) Query: 41 IHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAV 100 IHPSAV+ A +G V + Y + K+GN + + + +T +G+ + + A+ Sbjct: 7 IHPSAVIEEGAQLGDDVVIEAYAYVSKDAKIGNNVVIKQGARILSDTTIGDHSRVFSYAI 66 Query: 101 VGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSSKP 160 VGD +P QD+ YK + + IG N IREF +I+ + Sbjct: 67 VGD-IP---------------------QDISYKEEQKSGVVIGKNATIREFATINSGTAK 104 Query: 161 SDK-TVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFCH 219 D T IGDN IM CHIAHDC +G+ I ANN LAGHV + D T G + +HQF Sbjct: 105 GDGFTRIGDNAFIMAYCHIAHDCLLGNNIILANNATLAGHVELGDFTVVGGLTPIHQFVK 164 Query: 220 IGSFAFIGGGSVVSQDVPKYMMVAGERAELRGLNLEGLRRNGFTMSEMKSLRAAYRKIFM 279 +G I G S +SQD+ + + G RA +R LNL G+RR F E+ L A++ +F Sbjct: 165 VGEGCMIAGASALSQDIVPFCLAEGNRASIRSLNLVGIRRR-FDKDEVDRLSRAFKTLFR 223 Query: 280 STETVSLSFEERLTELEQDQELYSVPAVSAMLQSIRDSFTESRRGICKFR 329 + +E L ++QE +V + + E++RGI +R Sbjct: 224 QGD-----LKENAKNLLENQESENVKKMCHFI-------LETKRGIPVYR 261 >3I3A-A nrPDB Length = 259 Score = 149 bits (377), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 91/289 (31%), Positives = 143/289 (49%), Gaps = 32/289 (11%) Query: 41 IHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAV 100 IHP+A++ P A + + V VGPY I +V + G + + +E+G+ GAV Sbjct: 3 IHPTAIIDPKAELHESVEVGPYSIIEGNVSIQEGTIIEGHVKICAGSEIGKFNRFHQGAV 62 Query: 101 VGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSSKP 160 +G V QDL + IG++N RE+ +IH+ +K Sbjct: 63 IG----------------------VMPQDLGFNQQLLTKTVIGDHNIFREYSNIHKGTKE 100 Query: 161 SDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFCHI 220 TVIG+ N MG+ H+ HDC +G+ NI + +LAGHV + + +G VHQFC + Sbjct: 101 DSPTVIGNKNYFMGNSHVGHDCILGNNNILTHGAVLAGHVTLGNFAFISGLVAVHQFCFV 160 Query: 221 GSFAFIGGGSVVSQDVPKYMMVAGERAELRGLNLEGLRRNGFTMSEMKSLRAAYRKIFMS 280 G ++ + G + V QDVP Y V G + + GLN G++R GF+ +++ AY+ I+ S Sbjct: 161 GDYSMVAGLAKVVQDVPPYSTVDGNPSTVVGLNSVGMKRAGFSPEVRNAIKHAYKVIYHS 220 Query: 281 TETVSLSFEERLTELEQDQELYSVPAVSAMLQSIRDSFTESRRGICKFR 329 +S + L ELE L + V +++ RD S RG+ R Sbjct: 221 ----GISTRKALDELEASGNL--IEQVKYIIKFFRD----SDRGVTNHR 259 >4IHG-A nrPDB Length = 348 Score = 71.2 bits (173), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 67/263 (25%), Positives = 118/263 (44%), Gaps = 43/263 (16%) Query: 37 SEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLM 96 + V I +AV+ +G V +G C +G + K+G G +L+ + ++ ++G++C++ Sbjct: 121 NNVSIGANAVIESGVELGDNVIIGAGCFVGKNSKIGAGSRLWANVTIYHEIQIGQNCLIQ 180 Query: 97 TGAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHR 156 +G VVG + GY N G+ VK + + IG+ EI +I R Sbjct: 181 SGTVVGADGFGYA-----NDRGNW----VKIPQIGR-------VIIGDRVEIGACTTIDR 224 Query: 157 SSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQ 216 + D T+IG+ +I C IAH+ VV+ DNT AG ++ Sbjct: 225 GAL--DDTIIGNGVIIDNQCQIAHN------------------VVIGDNTAVAGGVIMAG 264 Query: 217 FCHIGSFAFIGGGSVVS--QDVPKYMMVAGERAELRGLNLEGLRRNGFTMSEMKSLRAAY 274 IG + IGG SV++ ++ + V G +R + G+ +G + K R Sbjct: 265 SLKIGRYCMIGGASVINGHMEICDKVTVTGMGMVMRPITEPGVYSSGIPLQPNKVWRKT- 323 Query: 275 RKIFMSTETVSLSFEERLTELEQ 297 + M+ + +S +RL LE+ Sbjct: 324 AALVMNIDDMS----KRLKSLER 342 >4E79-A nrPDB Length = 357 Score = 57.8 bits (138), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 56/205 (27%), Positives = 85/205 (41%), Gaps = 28/205 (13%) Query: 33 DSRDSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGES 92 D + S I +A +HP+AVI + +G Y IG + +G+ + + + N E+G+ Sbjct: 97 DKKISSTGIESTARIHPSAVISETAYIGHYVVIGENCVVGDNTVIQSHTKLDDNVEVGKD 156 Query: 93 C-----VLMTGAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNE 147 C V +TG+ +L I + +IG Q ++ + IGN+ Sbjct: 157 CFIDSYVTITGS---SKLRDRVRIHSSTVIGGEGFGFAPYQGKWHRIAQLGSVLIGNDVR 213 Query: 148 IREFCSIHRSSKPSDKTV------------------IGDNNLIMGSCHIAHDCKIGDRNI 189 I CSI R + D T+ IG N I C IA KIG I Sbjct: 214 IGSNCSIDRGAL--DNTILEDGVIIDNLVQIAHNVHIGSNTAIAAKCGIAGSTKIGKNCI 271 Query: 190 FANNTLLAGHVVVEDNTHTAGASVV 214 A +AGH+ + DN G S+V Sbjct: 272 LAGACGVAGHLSIADNVTLTGMSMV 296 Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust. Identities = 53/214 (24%), Positives = 81/214 (37%), Gaps = 54/214 (25%) Query: 36 DSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSS------------VKLGNGCKLYPSSHV 83 +S IHPSAV+ A IG V +G C +G + V++G C + + Sbjct: 106 ESTARIHPSAVISETAYIGHYVVIGENCVVGDNTVIQSHTKLDDNVEVGKDCFIDSYVTI 165 Query: 84 FGNTELGESCVLMTGAVVGDELPGYTFIGCNN-----------IIGHHAVVGVKCQDLKY 132 G+++L + + + V+G E G+ F +IG+ +G C + Sbjct: 166 TGSSKLRDRVRIHSSTVIGGE--GFGFAPYQGKWHRIAQLGSVLIGNDVRIGSNCS-IDR 222 Query: 133 KHGDECFL----------------CIGNNNEIREFCSIHRSSKPSDKTVIGDNNLIMGSC 176 D L IG+N I C I S+K IG N ++ G+C Sbjct: 223 GALDNTILEDGVIIDNLVQIAHNVHIGSNTAIAAKCGIAGSTK------IGKNCILAGAC 276 Query: 177 HIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAG 210 +A I D N L G +V N AG Sbjct: 277 GVAGHLSIAD------NVTLTGMSMVTKNISEAG 304 >3PMO-A nrPDB Length = 372 Score = 57.0 bits (136), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 52/197 (26%), Positives = 83/197 (42%), Gaps = 36/197 (18%) Query: 36 DSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVL 95 D + AV+ A IG GVS+G +C IG+ +G G L P ++ + +G + Sbjct: 135 DPSASVGAYAVIESGARIGAGVSIGAHCVIGARSVIGEGGWLAPRVTLYHDVTIGARVSI 194 Query: 96 MTGAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIH 155 +GAV+G E G+ F + A +G + IG++ EI +I Sbjct: 195 QSGAVIGGE--GFGFANEKGVWQKIAQIG--------------GVTIGDDVEIGANTTID 238 Query: 156 RSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRN------------------IFANNTLLA 197 R + SD T+IG+ + IAH+ +IGD + A L Sbjct: 239 RGAL-SD-TLIGNGVKLDNQIMIAHNVQIGDHTAMAACVGISGSAKIGRHCMLAGGVGLV 296 Query: 198 GHVVVEDNTHTAGASVV 214 GH+ + DN G ++V Sbjct: 297 GHIEICDNVFVTGMTMV 313 >2IUA-A nrPDB Length = 374 Score = 50.4 bits (119), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 47/189 (24%), Positives = 78/189 (41%), Gaps = 29/189 (15%) Query: 41 IHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAV 100 IHP+AV+HP A+I V + PY + +G+ C + S + + +GE + V Sbjct: 127 IHPTAVIHPTAIIEDHVCIEPYAVVCQHAHVGSACHIGSGSVIGAYSTVGEHSYIHPRVV 186 Query: 101 VGDELPGYTFIGCNNIIGHHAVVGVKC----------QDLKYKHGDECFL----CIGNNN 146 + + + IG II AV+G C Q KH + + IG N Sbjct: 187 IRERVS----IGKRVIIQPGAVIG-SCGFGYVTSAFGQHKHLKHLGKVIIEDDVEIGANT 241 Query: 147 EI----------REFCSIHRSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLL 196 I RE I + + + +G +++I+ IA KIG+ I + Sbjct: 242 TIDRGRFKHSVVREGSKIDNLVQIAHQVEVGQHSMIVAQAGIAGSTKIGNHVIIGGQAGI 301 Query: 197 AGHVVVEDN 205 GH+ + D+ Sbjct: 302 TGHICIADH 310 >4M9C-A nrPDB Length = 216 Score = 46.2 bits (108), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 5/78 (6%) Query: 177 HIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFCH-----IGSFAFIGGGSV 231 ++AHDC IGD FA G++ +ED+ + +V+ Q IG A +G G+V Sbjct: 135 YVAHDCVIGDYVTFAPGAKCNGNIHIEDHAYIGTGAVIKQGTPDKPLIIGKGAIVGMGAV 194 Query: 232 VSQDVPKYMMVAGERAEL 249 V++ VP + V G A + Sbjct: 195 VTKSVPAGVTVVGNPARI 212 Score = 28.9 bits (63), Expect = 3.2, Method: Compositional matrix adjust. Identities = 32/120 (26%), Positives = 48/120 (40%), Gaps = 4/120 (3%) Query: 8 REKLLSPLVSSTIRRL---SSSLSYSREDSRDSEVLIHPSAVVHPNAVIGKGVSVGPYCT 64 REKL+S L ++ L S++ E L+ P + N IGK Y Sbjct: 76 REKLVSLLEKDGVQHLAVQSTNTVILDEVEIGEGSLLCPFTCLTSNIKIGKFFHANIYSY 135 Query: 65 IGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVVGDELPGYTF-IGCNNIIGHHAVV 123 + +G+ P + GN + + + TGAV+ P IG I+G AVV Sbjct: 136 VAHDCVIGDYVTFAPGAKCNGNIHIEDHAYIGTGAVIKQGTPDKPLIIGKGAIVGMGAVV 195 >4MFG-A nrPDB Length = 168 Score = 41.6 bits (96), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 38/143 (26%), Positives = 65/143 (45%), Gaps = 35/143 (24%) Query: 104 ELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSSKPSDK 163 ++ G IG ++ I ++AVV GDE + IG N I++ +H ++ Sbjct: 26 DVIGNVKIGKDSSIWYNAVV----------RGDEGPITIGENTNIQDCSIVHGDTE---- 71 Query: 164 TVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFCHIGSF 223 T+IG NN+ +G I H CKI D N L+ ++ DN IG + Sbjct: 72 TIIG-NNVTVGHRSIVHGCKISD------NVLIGMGSIILDN------------AEIGEY 112 Query: 224 AFIGGGSVVS--QDVPKYMMVAG 244 IG G++++ + P +++ G Sbjct: 113 TLIGAGTLITSNKKFPPGVLIMG 135 >1XHD-A nrPDB Length = 173 Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust. Identities = 39/147 (26%), Positives = 62/147 (42%), Gaps = 39/147 (26%) Query: 135 GDECFLCIGNNNEIREFCSIHRSSK-P---SDKTVIGDNNLIMGSCHIAHDCKIGDRNIF 190 GD IG+ +++ C++H+S + P D +G + +I+ SCHI D IG Sbjct: 47 GDVSPTIIGDRVNVQDQCTLHQSPQYPLILEDDVTVG-HQVILHSCHIKKDALIG----- 100 Query: 191 ANNTLLAGHVVVEDNTHTAGASVVHQFCHIGSFAFIGGGSVVSQ--DVPKYMMVAGERAE 248 S++ IG AFIG GS+VSQ +P + G A+ Sbjct: 101 -------------------MGSIILDGAEIGEGAFIGAGSLVSQGKKIPPNTLAFGRPAK 141 Query: 249 -LRGLNLEGLRRNGFTMSEMKSLRAAY 274 +R L E + +M+ +R Y Sbjct: 142 VIRELTAEDRK-------DMERIRTQY 161 >3NZ2-A nrPDB Length = 195 Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust. Identities = 22/67 (32%), Positives = 36/67 (53%), Gaps = 4/67 (5%) Query: 200 VVVEDNTHTAGASVVHQFCHIGSFAFIGGGSVVSQDVPKYMMVAGERAELRGLNLEGLRR 259 +V+ED+ G V++Q IG+ + + SVV+QDVP +V G A + L L+ Sbjct: 133 IVIEDDVWIGGNVVINQGVTIGARSVVAANSVVNQDVPPDTLVGGTPARI----LRSLKD 188 Query: 260 NGFTMSE 266 +M+E Sbjct: 189 PAESMAE 195 >4G3P-A nrPDB Length = 501 Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust. Identities = 47/193 (24%), Positives = 75/193 (38%), Gaps = 28/193 (14%) Query: 59 VGPYCT-IGSSVKLGNGCKLYPSSHVFGNTELGESCVL-----MTGAVVGDELPGYTFIG 112 V P T I V +G ++P + + G T++G CV+ +T VGD G Sbjct: 273 VDPATTWIDVDVTIGRDTVIHPGTQLLGRTQIGGRCVVGPDTTLTDVAVGDGASVVRTHG 332 Query: 113 CNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSSKPSDKTVIGDNNLI 172 ++ IG A VG Y +G + ++ F + S+ + V + Sbjct: 333 SSSSIGDGAAVG----PFTYL---RPGTALGADGKLGAFVEVKNSTIGTGTKV--PHLTY 383 Query: 173 MGSCHIAHDCKIGDRNIFAN-------NTLLAGHVVVEDNTHTAGASVVHQFCHIGSFAF 225 +G I IG ++F N T + HV T ++ IG A+ Sbjct: 384 VGDADIGEYSNIGASSVFVNYDGTSKRRTTVGSHV------RTGSDTMFVAPVTIGDGAY 437 Query: 226 IGGGSVVSQDVPK 238 G G+VV +DVP Sbjct: 438 TGAGTVVREDVPP 450 >3MQG-A nrPDB Length = 192 Score = 38.9 bits (89), Expect = 0.003, Method: Compositional matrix adjust. Identities = 42/208 (20%), Positives = 78/208 (37%), Gaps = 56/208 (26%) Query: 45 AVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVVGDE 104 A +HP A++ +G +G + +++ H+ G E+GE C L VG+ Sbjct: 4 ATIHPTAIVDEGARIGAHS------------RIWHWVHICGGAEIGEGCSLGQNVFVGNR 51 Query: 105 LPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSSKPSDKT 164 + IGN +I+ S++ + D Sbjct: 52 VR-----------------------------------IGNRVKIQNNVSVYDNVFLEDDV 76 Query: 165 VIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFCHIGSFA 224 G + + + I ++ + + + G + + T GA+ IG +A Sbjct: 77 FCGPSMVFTNVYN--PRAAIERKSEYRDTIVRQGATLGANCTVVCGAT-------IGRYA 127 Query: 225 FIGGGSVVSQDVPKYMMVAGERAELRGL 252 F+G G+VV++DVP + +V G A G Sbjct: 128 FVGAGAVVNKDVPDFALVVGVPARQIGW 155 >1OCX-A nrPDB Length = 182 Score = 36.2 bits (82), Expect = 0.019, Method: Compositional matrix adjust. Identities = 26/87 (29%), Positives = 40/87 (45%), Gaps = 6/87 (6%) Query: 166 IGDNNLIMGSCHI---AHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFCHIGS 222 IGDN ++ HI H RN A L V + +N G +V++ IG Sbjct: 95 IGDNCMLAPGVHIYTATHPIDPVARNSGAE---LGKPVTIGNNVWIGGRAVINPGVTIGD 151 Query: 223 FAFIGGGSVVSQDVPKYMMVAGERAEL 249 + G+VV++DVP ++V G A + Sbjct: 152 NVVVASGAVVTKDVPDNVVVGGNPARI 178 Score = 31.6 bits (70), Expect = 0.50, Method: Compositional matrix adjust. Identities = 20/76 (26%), Positives = 36/76 (47%), Gaps = 8/76 (10%) Query: 41 IHPSAVVHPNAVIGK--GVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTG 98 +H HP + + G +G TIG++V +G + P +G++ V+ +G Sbjct: 105 VHIYTATHPIDPVARNSGAELGKPVTIGNNVWIGGRAVINPG------VTIGDNVVVASG 158 Query: 99 AVVGDELPGYTFIGCN 114 AVV ++P +G N Sbjct: 159 AVVTKDVPDNVVVGGN 174 >4H7O-A nrPDB Length = 281 Score = 36.2 bits (82), Expect = 0.023, Method: Compositional matrix adjust. Identities = 39/151 (25%), Positives = 63/151 (41%), Gaps = 29/151 (19%) Query: 118 GHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCS--IHRSSK--------PSDKTVIG 167 G+HA+ G + + ++ G + L N+I C IH +++ + VIG Sbjct: 107 GYHALQGYRVANWLWRQGRKA-LATYFQNQISVACQVDIHPAARIGRGIMLDHATGIVIG 165 Query: 168 DNNLIMGSCHIAHDCKIG-------DRNIFANNTLLAGHVVVEDNTHTAGASVVHQFCHI 220 + ++ I D +G DR+ ++ G AGA ++ + Sbjct: 166 ETAVVEDDVSILQDVTLGGTGKECGDRHPKIREGVMIG----------AGAKILGNI-EV 214 Query: 221 GSFAFIGGGSVVSQDVPKYMMVAGERAELRG 251 G A IG GSVV Q VP + VAG A + G Sbjct: 215 GEGAKIGSGSVVLQAVPPHTTVAGVPARIVG 245 Score = 29.3 bits (64), Expect = 2.4, Method: Compositional matrix adjust. Identities = 24/96 (25%), Positives = 42/96 (43%), Gaps = 22/96 (22%) Query: 38 EVLIHPSA--------------VVHPNAVIGKGVSVGPYCTIGSS--------VKLGNGC 75 +V IHP+A V+ AV+ VS+ T+G + K+ G Sbjct: 141 QVDIHPAARIGRGIMLDHATGIVIGETAVVEDDVSILQDVTLGGTGKECGDRHPKIREGV 200 Query: 76 KLYPSSHVFGNTELGESCVLMTGAVVGDELPGYTFI 111 + + + GN E+GE + +G+VV +P +T + Sbjct: 201 MIGAGAKILGNIEVGEGAKIGSGSVVLQAVPPHTTV 236 >1KRR-A nrPDB Length = 203 Score = 35.0 bits (79), Expect = 0.042, Method: Compositional matrix adjust. Identities = 28/109 (25%), Positives = 50/109 (45%), Gaps = 2/109 (1%) Query: 138 CFLCIGNNNEI-REFCSIHRSSKPSDKTV-IGDNNLIMGSCHIAHDCKIGDRNIFANNTL 195 + G+N I R F + + D TV IGDN LI + ++ + N + Sbjct: 68 VYFSYGSNIHIGRNFYANFNLTIVDDYTVTIGDNVLIAPNVTLSVTGHPVHHELRKNGEM 127 Query: 196 LAGHVVVEDNTHTAGASVVHQFCHIGSFAFIGGGSVVSQDVPKYMMVAG 244 + + + +N V++ IG + IG GS+V++D+P ++ AG Sbjct: 128 YSFPITIGNNVWIGSHVVINPGVTIGDNSVIGAGSIVTKDIPPNVVAAG 176 >3TIO-A nrPDB Length = 183 Score = 34.7 bits (78), Expect = 0.053, Method: Compositional matrix adjust. Identities = 33/121 (27%), Positives = 57/121 (47%), Gaps = 10/121 (8%) Query: 135 GDECFLCIGNNNEIREFCSIHRSSKPS-----DKTVIGDNNLIMGSCHIAHDCKIGDRNI 189 GD ++ IG I++ +H + K S + IG++ + +G + H C IG+R + Sbjct: 46 GDVHYVQIGARTNIQDGSMLHVTHKSSYNPDGNPLTIGED-VTVGHKVMLHGCTIGNRVL 104 Query: 190 FANNTLLAGHVVVEDNTHTAGASVVHQFCHIGSFAFIGGGSVVSQDVPKYMMVAGERAEL 249 ++L +VED+ S+V Q + S ++ GS V Q P + E+A L Sbjct: 105 VGMGSILLDGAIVEDDVMIGAGSLVPQNKRLES-GYLYLGSPVKQIRP---LSDEEKAGL 160 Query: 250 R 250 R Sbjct: 161 R 161 >2P2O-A nrPDB Length = 185 Score = 34.7 bits (78), Expect = 0.053, Method: Compositional matrix adjust. Identities = 27/87 (31%), Positives = 40/87 (45%), Gaps = 6/87 (6%) Query: 166 IGDNNLIMGSCHI---AHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFCHIGS 222 IGD+ I HI H +RN + VV+ N G +V++ IG Sbjct: 97 IGDHCFIGPGVHIYTATHPLDPHERN---SGLEYGKPVVIGHNVWIGGRAVINPGVTIGD 153 Query: 223 FAFIGGGSVVSQDVPKYMMVAGERAEL 249 A I G+VV++DVP +V G A++ Sbjct: 154 NAVIASGAVVTKDVPANAVVGGNPAKV 180 >3IGJ-A nrPDB Length = 190 Score = 34.7 bits (78), Expect = 0.058, Method: Compositional matrix adjust. Identities = 16/50 (32%), Positives = 29/50 (58%) Query: 200 VVVEDNTHTAGASVVHQFCHIGSFAFIGGGSVVSQDVPKYMMVAGERAEL 249 V + +N G ++++ IG A I G+VV++DVP ++V G A++ Sbjct: 135 VKIGNNVWVGGGAIINPGVSIGDNAVIASGAVVTKDVPNNVVVGGNPAKV 184 Score = 30.4 bits (67), Expect = 1.2, Method: Compositional matrix adjust. Identities = 21/73 (28%), Positives = 34/73 (46%), Gaps = 10/73 (13%) Query: 42 HPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVV 101 HP V N+ G G IG++V +G G + P +G++ V+ +GAVV Sbjct: 118 HPLHPVERNS----GKEYGKPVKIGNNVWVGGGAIINPG------VSIGDNAVIASGAVV 167 Query: 102 GDELPGYTFIGCN 114 ++P +G N Sbjct: 168 TKDVPNNVVVGGN 180 >1HM0-A nrPDB Length = 468 Score = 34.7 bits (78), Expect = 0.058, Method: Compositional matrix adjust. Identities = 48/196 (24%), Positives = 80/196 (40%), Gaps = 15/196 (7%) Query: 56 GVS-VGPYCT-IGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVVGDELPGYTFIGC 113 GVS V P T I V++ ++ + + G T++G VL G V D G + Sbjct: 260 GVSFVNPEATYIDIDVEIAPEVQIEANVILKGQTKIGAETVLTNGTYVVDSTIGAGAVIT 319 Query: 114 NNIIGHHAVV-GVKCQDLKYKHGDECF---LCIGNNNEIREFCSIHRSSKPSDKTVIGDN 169 N++I +V GV + + + IGN E++ SI ++K T IG+ Sbjct: 320 NSMIEESSVADGVTVGPYAHIRPNSSLGAQVHIGNFVEVKG-SSIGENTKAGHLTYIGN- 377 Query: 170 NLIMGSCHIAHDCKIGDRNIFANNTLLAGH-VVVEDNTHTAGASVVHQFCHIGSFAFIGG 228 C + + G I N + V+ DN S + +G + +G Sbjct: 378 ------CEVGSNVNFGAGTITVNYDGKNKYKTVIGDNVFVGSNSTIIAPVELGDNSLVGA 431 Query: 229 GSVVSQDVPKYMMVAG 244 GS +++DVP + G Sbjct: 432 GSTITKDVPADAIAIG 447 >6I7T-G nrPDB Length = 712 Score = 34.3 bits (77), Expect = 0.084, Method: Compositional matrix adjust. Identities = 29/112 (25%), Positives = 50/112 (44%), Gaps = 8/112 (7%) Query: 50 NAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVVGDELPGYT 109 + V+ + +G IGS K+G G K+ +S + N ++GE+ + + D Sbjct: 330 DVVLAQSCKIGKCTAIGSGTKIGEGTKI-ENSVIGRNCQIGENIRIKNSFIWDD-----C 383 Query: 110 FIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSSKPS 161 IG N+II H + + D C IG N +I + + R++K S Sbjct: 384 IIGNNSIIDHSLIASNATLGSNVRLNDGCI--IGFNVKIDDNMDLDRNTKIS 433 >6JLY-I nrPDB Length = 678 Score = 33.9 bits (76), Expect = 0.11, Method: Compositional matrix adjust. Identities = 33/118 (27%), Positives = 53/118 (44%), Gaps = 26/118 (22%) Query: 89 LGESCVLMTGAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEI 148 L SC++ ++G YT +G +++ + ++G C IG+N Sbjct: 321 LARSCIIKARTLIG----AYTKVGDASVVAN-TIIGRNC-------------TIGSN--- 359 Query: 149 REFCSIHRSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNT 206 CSI + D VIGDN I G +A+ KIG+ + ++A VV+ DNT Sbjct: 360 ---CSIDSAFLWED-VVIGDNCRI-GKAILANSVKIGNNCSIEDGAIVAAGVVIGDNT 412 Score = 33.1 bits (74), Expect = 0.19, Method: Compositional matrix adjust. Identities = 23/79 (29%), Positives = 40/79 (50%), Gaps = 12/79 (15%) Query: 45 AVVHPNAVIGKGVSVGPYCTIGSS-----VKLGNGCKLYPSSHVFGNT-ELGESCVLMTG 98 A V N +IG+ ++G C+I S+ V +G+ C++ + N+ ++G +C + G Sbjct: 342 ASVVANTIIGRNCTIGSNCSIDSAFLWEDVVIGDNCRI--GKAILANSVKIGNNCSIEDG 399 Query: 99 AVVGDELPGYTFIGCNNII 117 A+V IG N II Sbjct: 400 AIVA----AGVVIGDNTII 414 >4ISX-A nrPDB Length = 188 Score = 33.5 bits (75), Expect = 0.12, Method: Compositional matrix adjust. Identities = 22/82 (26%), Positives = 34/82 (41%) Query: 163 KTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFCHIGS 222 K IGDN ++ + I D + + V + DN G ++ IG Sbjct: 96 KIEIGDNVMLAPNVQIYTAYHPIDAQLRNSGIEYGSPVKIGDNVWIGGGVIITPGITIGD 155 Query: 223 FAFIGGGSVVSQDVPKYMMVAG 244 IG GSVV++D+P + G Sbjct: 156 NVVIGAGSVVTKDIPPNTVAVG 177 >2NPO-A nrPDB Length = 207 Score = 33.5 bits (75), Expect = 0.13, Method: Compositional matrix adjust. Identities = 33/112 (29%), Positives = 54/112 (48%), Gaps = 25/112 (22%) Query: 40 LIHPSAVVHPNAVI--GKGVSVGPYCTIGSSVKLGNG------------CKLYPSSHV-- 83 LIH SA++ P+A++ G+ + PY I + K+ G C + SHV Sbjct: 80 LIHKSALISPSAIVEENAGILIMPYVVINAKAKIEKGVILNTSSVIEHECVIGEFSHVSV 139 Query: 84 ----FGNTELGESCVLMTGAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLK 131 GN ++G++C L + V LP + + ++I+G A + VK QD K Sbjct: 140 GAKCAGNVKIGKNCFLGINSCV---LPNLS-LADDSILGGGATL-VKNQDEK 186 Score = 30.0 bits (66), Expect = 1.4, Method: Compositional matrix adjust. Identities = 23/65 (35%), Positives = 35/65 (53%), Gaps = 4/65 (6%) Query: 39 VLIHPSAVVHPNAVIGK--GVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLM 96 V+++ S+V+ VIG+ VSVG C +VK+G C L +S V N L + +L Sbjct: 117 VILNTSSVIEHECVIGEFSHVSVGAKCA--GNVKIGKNCFLGINSCVLPNLSLADDSILG 174 Query: 97 TGAVV 101 GA + Sbjct: 175 GGATL 179 >4DCL-A nrPDB Length = 207 Score = 32.3 bits (72), Expect = 0.26, Method: Compositional matrix adjust. Identities = 26/85 (30%), Positives = 36/85 (42%), Gaps = 6/85 (7%) Query: 163 KTVIGDNNLIMGSCHI---AHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFCH 219 + IGDN I +C H RN AG + + NT G V Sbjct: 94 QITIGDNVFIGPNCGFYTATHPLNFHHRN---EGFEKAGPIHIGSNTWFGGHVAVLPGVT 150 Query: 220 IGSFAFIGGGSVVSQDVPKYMMVAG 244 IG + IG GSVV++D+P + + G Sbjct: 151 IGEGSVIGAGSVVTKDIPPHSLAVG 175 >4N6B-A nrPDB Length = 286 Score = 32.3 bits (72), Expect = 0.29, Method: Compositional matrix adjust. Identities = 27/93 (29%), Positives = 43/93 (46%), Gaps = 22/93 (23%) Query: 39 VLIHPSA--------------VVHPNAVIGKGVSVGPYCTIGSS--------VKLGNGCK 76 V IHP+A VV AVIG VS+ + T+G + K+G+G Sbjct: 153 VDIHPAARIGKGILFDHATGVVVGETAVIGNNVSILHHVTLGGTGKVGGDRHPKIGDGVL 212 Query: 77 LYPSSHVFGNTELGESCVLMTGAVVGDELPGYT 109 + + + GN ++GE + G+VV ++P T Sbjct: 213 IGAGATILGNIKIGEGAKVGAGSVVLIDVPPRT 245 Score = 31.2 bits (69), Expect = 0.68, Method: Compositional matrix adjust. Identities = 29/91 (31%), Positives = 41/91 (45%), Gaps = 12/91 (13%) Query: 162 DKTVIGDNNLIMGSCHIAHDCKIG-DRNIFANNTLLAGHVVVEDNTHTAGASVVHQFCHI 220 + VIG+N I+ + K+G DR+ + +L G AGA+++ I Sbjct: 177 ETAVIGNNVSILHHVTLGGTGKVGGDRHPKIGDGVLIG----------AGATILGNI-KI 225 Query: 221 GSFAFIGGGSVVSQDVPKYMMVAGERAELRG 251 G A +G GSVV DVP G A L G Sbjct: 226 GEGAKVGAGSVVLIDVPPRTTAVGNPARLVG 256 >3R8Y-A nrPDB Length = 240 Score = 32.0 bits (71), Expect = 0.35, Method: Compositional matrix adjust. Identities = 30/114 (26%), Positives = 42/114 (36%), Gaps = 26/114 (22%) Query: 162 DKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFCHIG 221 D IGDN +IM + I IG+ ++ N +L G V N H +V+ Sbjct: 102 DHVEIGDNAVIMMNATINIGAVIGEGSMIDMNAVLGGRATVGKNCHVGAGAVLAGVIEPP 161 Query: 222 SF--------AFIGGGSVV------------------SQDVPKYMMVAGERAEL 249 S IG VV ++DVP Y +VAG A + Sbjct: 162 SAKPVIVEDDVVIGANVVVLEGVTVGKGAVVAAGAVVTEDVPPYTVVAGTPARV 215 >5VMK-A nrPDB Length = 462 Score = 30.8 bits (68), Expect = 0.92, Method: Compositional matrix adjust. Identities = 45/199 (22%), Positives = 80/199 (40%), Gaps = 39/199 (19%) Query: 68 SVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVVGDELPGYTFIGCNNIIGHHAVV-GVK 126 +VK+G+ ++ + + GN ELG+ + IG I+ + + G K Sbjct: 270 TVKVGHDVRIDVNVIIEGNCELGD----------------FVEIGAGCILKNTTIAAGTK 313 Query: 127 CQDLKYKHGDECFLCIGNNNEIREFCSIHRSSKPSDKTVIGD-----NNLIMGSCHIAHD 181 Q G +G N +I F + +K +++ IG+ N I H Sbjct: 314 VQAYSVFDG----AVVGENTQIGPFARLRPGAKLANEVHIGNFVEVKNTTIGLGSKANHF 369 Query: 182 CKIGDRNIFANNTLLAGHVV------------VEDNTHTAGASVVHQFCHIGSFAFIGGG 229 +GD I A + + AG + + D S + IG+ A +G G Sbjct: 370 TYLGDAEIGAESNIGAGTITCNYDGANKHKTTIGDAVFIGSNSSLVAPVTIGNGATVGAG 429 Query: 230 SVVSQDVPKYMMVAGERAE 248 SV+++DV + + + ERA+ Sbjct: 430 SVITKDVAEQSL-SFERAQ 447 >2QKX-A nrPDB Length = 391 Score = 30.0 bits (66), Expect = 1.5, Method: Compositional matrix adjust. Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 6/72 (8%) Query: 59 VGPYCT-IGSSVKLGNGCKLYPSSHVFGNTELGESCVL-----MTGAVVGDELPGYTFIG 112 V P T I V +G ++P + + G T++G CV+ +T VGD G Sbjct: 269 VDPATTWIDVDVTIGRDTVIHPGTQLLGRTQIGGRCVVGPDTTLTDVAVGDGASVVRTHG 328 Query: 113 CNNIIGHHAVVG 124 ++ IG A VG Sbjct: 329 SSSSIGDGAAVG 340 >5K1Q-A nrPDB Length = 355 Score = 29.6 bits (65), Expect = 2.0, Method: Compositional matrix adjust. Identities = 23/84 (27%), Positives = 34/84 (40%), Gaps = 8/84 (9%) Query: 196 LAGHVVVEDNTHTAGASVVHQFCHIGSFA---FIGGGSVVSQDVPKYMMVAGERAELRGL 252 +AG V D H G + Q H G A F GGG V++ P + G +R L Sbjct: 88 IAGWRKVTDAVHANGGKIFVQLWHTGRVAHPHFFGGGDVLA---PSAQKIEGSVPRMREL 144 Query: 253 NLEGLRRNGFTMSEMKSLRAAYRK 276 + T+ +++ L Y K Sbjct: 145 TY--VTPKAVTVEDIQGLVRDYAK 166 >2OI7-A nrPDB Length = 456 Score = 28.9 bits (63), Expect = 2.9, Method: Compositional matrix adjust. Identities = 36/147 (24%), Positives = 54/147 (36%), Gaps = 41/147 (27%) Query: 23 LSSSLSYSREDSRDSEVLIHPSAV-----------VHPNAVIGKGVSVGPY--------- 62 L +L++ R+ D+ V+I + V N+VIG + PY Sbjct: 262 LRGTLTHGRDVEIDTNVIIEGNVTLGHRVKIGTGCVIKNSVIGDDCEISPYTVVEDANLA 321 Query: 63 --CTIGSSVKLGNGCKLYPSSHVFGNTELGES----------CVLMTGAVVGDELP-GYT 109 CTIG +L G +L +HV E+ ++ + A +GD + G Sbjct: 322 AACTIGPFARLRPGAELLEGAHVGNFVEMKKARLGKGSKAGHLTYLGDAEIGDNVNIGAG 381 Query: 110 FIGCN--------NIIGHHAVVGVKCQ 128 I CN IIG VG Q Sbjct: 382 TITCNYDGANKFKTIIGDDVFVGSDTQ 408 >2YWH-A nrPDB Length = 600 Score = 28.9 bits (63), Expect = 3.0, Method: Compositional matrix adjust. Identities = 23/74 (31%), Positives = 29/74 (39%), Gaps = 1/74 (1%) Query: 121 AVVGVKCQDLKYKHGDECFLC-IGNNNEIREFCSIHRSSKPSDKTVIGDNNLIMGSCHIA 179 AV V+ D + K GD+ L G E+ E + DK GD I S Sbjct: 208 AVAFVRIFDGEVKPGDKIMLMSTGKEYEVTEVGAQTPKMTKFDKLSAGDVGYIAASIKDV 267 Query: 180 HDCKIGDRNIFANN 193 D +IGD A N Sbjct: 268 RDIRIGDTITHAKN 281 >1T3D-A nrPDB Length = 289 Score = 28.9 bits (63), Expect = 3.1, Method: Compositional matrix adjust. Identities = 18/43 (41%), Positives = 23/43 (53%), Gaps = 1/43 (2%) Query: 209 AGASVVHQFCHIGSFAFIGGGSVVSQDVPKYMMVAGERAELRG 251 AGA ++ +G A IG GSVV Q VP + AG A + G Sbjct: 220 AGAKILGNI-EVGRGAKIGAGSVVLQPVPPHTTAAGVPARIVG 261 Score = 28.1 bits (61), Expect = 5.7, Method: Compositional matrix adjust. Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 22/94 (23%) Query: 38 EVLIHPSA--------------VVHPNAVIGKGVSVGPYCTIGSSVKLG--------NGC 75 +V IHP+A VV AVI VS+ T+G + K G G Sbjct: 157 QVDIHPAAKIGRGIMLDHATGIVVGETAVIENDVSILQSVTLGGTGKSGGDRHPKIREGV 216 Query: 76 KLYPSSHVFGNTELGESCVLMTGAVVGDELPGYT 109 + + + GN E+G + G+VV +P +T Sbjct: 217 MIGAGAKILGNIEVGRGAKIGAGSVVLQPVPPHT 250 >3CJ8-A nrPDB Length = 236 Score = 28.9 bits (63), Expect = 3.4, Method: Compositional matrix adjust. Identities = 15/55 (27%), Positives = 27/55 (49%), Gaps = 2/55 (3%) Query: 75 CKLYPSSHVFGNTELGESCVLMTGAV--VGDELPGYTFIGCNNIIGHHAVVGVKC 127 ++ P + + E+G+ V+M GA+ +G + T I ++G A VG C Sbjct: 92 ARIEPGALIREKVEIGDQAVIMMGAILNIGAVVGAGTMIDMGAVLGGRATVGKHC 146 >3GVD-A nrPDB Length = 276 Score = 28.9 bits (63), Expect = 3.6, Method: Compositional matrix adjust. Identities = 18/43 (41%), Positives = 23/43 (53%), Gaps = 1/43 (2%) Query: 209 AGASVVHQFCHIGSFAFIGGGSVVSQDVPKYMMVAGERAELRG 251 AGA ++ +G A IG GSVV Q VP + AG A + G Sbjct: 207 AGAKILGNI-EVGRGAKIGAGSVVLQSVPAHTTAAGVPARIVG 248 >1SST-A nrPDB Length = 267 Score = 28.9 bits (63), Expect = 3.7, Method: Compositional matrix adjust. Identities = 19/58 (32%), Positives = 30/58 (51%), Gaps = 3/58 (5%) Query: 209 AGASVVHQFCHIGSFAFIGGGSVVSQDVPKYMMVAGERAELRGLNLEGLRRNGFTMSE 266 AGA ++ +G +A IG SVV VP+Y AG A R ++ + + F M++ Sbjct: 200 AGAKILGNI-EVGKYAKIGANSVVLNPVPEYATAAGVPA--RIVSQDKAAKPAFDMNQ 254 >1A59-A nrPDB Length = 378 Score = 28.5 bits (62), Expect = 3.8, Method: Compositional matrix adjust. Identities = 11/36 (30%), Positives = 22/36 (61%) Query: 142 IGNNNEIREFCSIHRSSKPSDKTVIGDNNLIMGSCH 177 + N++E++ F + RS + D+ V G +L+ +CH Sbjct: 57 LPNDSELKAFVNFERSHRKLDENVKGAIDLLSTACH 92 >3TWD-A nrPDB Length = 222 Score = 28.5 bits (62), Expect = 4.8, Method: Compositional matrix adjust. Identities = 22/83 (26%), Positives = 34/83 (40%), Gaps = 22/83 (26%) Query: 23 LSSSLSYSREDSRDSEVLIHPSAV-----------VHPNAVIGKGVSVGPY--------- 62 L +L++ R+ D+ V+I + V N+VIG + PY Sbjct: 31 LRGTLTHGRDVEIDTNVIIEGNVTLGHRVKIGTGCVIKNSVIGDDCEISPYTVVEDANLA 90 Query: 63 --CTIGSSVKLGNGCKLYPSSHV 83 CTIG +L G +L +HV Sbjct: 91 AACTIGPFARLRPGAELLEGAHV 113 >6O85-A nrPDB Length = 721 Score = 28.1 bits (61), Expect = 5.0, Method: Compositional matrix adjust. Identities = 23/83 (27%), Positives = 41/83 (49%), Gaps = 3/83 (3%) Query: 24 SSSLSYSRED-SRDSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSH 82 + S ++SR + R EV + +++ N ++G G +G C I +SV +G GC + + Sbjct: 332 TQSCTHSRHNIYRGPEVSLGHGSILEENVLLGSGTVIGSNCFITNSV-IGPGCHI-GDNV 389 Query: 83 VFGNTELGESCVLMTGAVVGDEL 105 V T L + + GA + L Sbjct: 390 VLDQTYLWQGVRVAAGAQIHQSL 412 >6F3A-U nrPDB Length = 190 Score = 27.3 bits (59), Expect = 8.7, Method: Compositional matrix adjust. Identities = 34/140 (24%), Positives = 56/140 (40%), Gaps = 11/140 (7%) Query: 68 SVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVVGDELPGYTFIGCNNIIGHHAVVGVKC 127 SVK+ G + S + G+ +G V+ A + E G IG N+I A++ Sbjct: 8 SVKIAPGAVVCVESEIRGDVTIGPRTVIHPKARIIAEA-GPIVIGEGNLIEEQALIINAH 66 Query: 128 QDLKYKHGDEC---FLCIGNNNEIREFCSIHRSSKPSDKTVI------GDNNLIMGSCHI 178 D ++ + IG NN + E ++ K D VI G N ++ C I Sbjct: 67 PDNITPDAEDSEPKPMIIGTNN-VFEVGCYSQAMKMGDNNVIESKAYVGRNVILTSGCII 125 Query: 179 AHDCKIGDRNIFANNTLLAG 198 C + + NT++ G Sbjct: 126 GACCNLNTFEVIPENTVIYG 145 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3T57-A nrPDB 406 e-114 4E6U-A nrPDB 289 1e-78 2JF2-A nrPDB 285 2e-77 5JXX-A nrPDB 277 6e-75 4EQY-A nrPDB 275 2e-74 5F42-A nrPDB 273 8e-74 3I3A-A nrPDB 272 2e-73 5DEP-A nrPDB 269 1e-72 3R0S-A nrPDB 260 7e-70 4R36-A nrPDB 255 2e-68 1J2Z-A nrPDB 253 7e-68 4IHG-A nrPDB 185 3e-47 4E79-A nrPDB 162 2e-40 3PMO-A nrPDB 158 4e-39 2IUA-A nrPDB 142 2e-34 1XHD-A nrPDB 97 1e-20 4MFG-A nrPDB 95 4e-20 4M9C-A nrPDB 94 1e-19 3NZ2-A nrPDB 74 8e-14 Sequences not found previously or not previously below threshold: 1HM0-A nrPDB 76 2e-14 4DCL-A nrPDB 72 4e-13 3MQG-A nrPDB 68 4e-12 5VMK-A nrPDB 67 9e-12 1OCX-A nrPDB 66 1e-11 4N6B-A nrPDB 66 2e-11 1KRR-A nrPDB 66 2e-11 4G3P-A nrPDB 65 4e-11 4HUR-A nrPDB 65 4e-11 4ISX-A nrPDB 65 5e-11 3R8Y-A nrPDB 63 1e-10 2V0L-A nrPDB 63 2e-10 2P2O-A nrPDB 63 2e-10 3IGJ-A nrPDB 62 4e-10 1KK6-A nrPDB 60 1e-09 2OI7-A nrPDB 60 2e-09 3TWD-A nrPDB 58 5e-09 6MFK-A nrPDB 58 8e-09 1T3D-A nrPDB 56 2e-08 3TIO-A nrPDB 55 5e-08 6F3A-U nrPDB 55 5e-08 4H7O-A nrPDB 54 9e-08 3CJ8-A nrPDB 54 9e-08 3FWW-A nrPDB 53 2e-07 3GVD-A nrPDB 52 3e-07 5Z09-A nrPDB 51 5e-07 5AFU-U nrPDB 51 8e-07 1THJ-A nrPDB 51 8e-07 3Q1X-A nrPDB 51 9e-07 2NPO-A nrPDB 50 1e-06 6JLY-I nrPDB 50 1e-06 1XAT-A nrPDB 50 2e-06 6I7T-G nrPDB 50 2e-06 1SST-A nrPDB 49 3e-06 4HZC-A nrPDB 47 1e-05 5UX9-A nrPDB 45 6e-05 2QKX-A nrPDB 44 9e-05 6F1T-V nrPDB 44 1e-04 5NW4-h nrPDB 44 1e-04 6O85-A nrPDB 44 1e-04 3F1X-A nrPDB 43 1e-04 3EG4-A nrPDB 43 3e-04 6AMZ-A nrPDB 40 0.001 3BXY-A nrPDB 40 0.002 6I7T-I nrPDB 39 0.003 3GOS-A nrPDB 39 0.004 5B04-E nrPDB 38 0.005 1KGQ-A nrPDB 38 0.008 1FWY-A nrPDB 37 0.010 6CKT-A nrPDB 36 0.018 6EZO-E nrPDB 35 0.047 3TK8-A nrPDB 34 0.088 2RIJ-A nrPDB 34 0.10 2WLD-A nrPDB 31 1.1 5E3R-A nrPDB 29 2.7 6C5V-A nrPDB 29 2.9 3R5A-A nrPDB 28 5.3 >3T57-A nrPDB Length = 305 Score = 406 bits (1042), Expect = e-114, Method: Composition-based stats. Identities = 304/304 (100%), Positives = 304/304 (100%) Query: 33 DSRDSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGES 92 DSRDSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGES Sbjct: 2 DSRDSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGES 61 Query: 93 CVLMTGAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFC 152 CVLMTGAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFC Sbjct: 62 CVLMTGAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFC 121 Query: 153 SIHRSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGAS 212 SIHRSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGAS Sbjct: 122 SIHRSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGAS 181 Query: 213 VVHQFCHIGSFAFIGGGSVVSQDVPKYMMVAGERAELRGLNLEGLRRNGFTMSEMKSLRA 272 VVHQFCHIGSFAFIGGGSVVSQDVPKYMMVAGERAELRGLNLEGLRRNGFTMSEMKSLRA Sbjct: 182 VVHQFCHIGSFAFIGGGSVVSQDVPKYMMVAGERAELRGLNLEGLRRNGFTMSEMKSLRA 241 Query: 273 AYRKIFMSTETVSLSFEERLTELEQDQELYSVPAVSAMLQSIRDSFTESRRGICKFRQWL 332 AYRKIFMSTETVSLSFEERLTELEQDQELYSVPAVSAMLQSIRDSFTESRRGICKFRQWL Sbjct: 242 AYRKIFMSTETVSLSFEERLTELEQDQELYSVPAVSAMLQSIRDSFTESRRGICKFRQWL 301 Query: 333 DSTT 336 DSTT Sbjct: 302 DSTT 305 >4E6U-A nrPDB Length = 265 Score = 289 bits (739), Expect = 1e-78, Method: Composition-based stats. Identities = 123/289 (42%), Positives = 170/289 (58%), Gaps = 33/289 (11%) Query: 40 LIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGA 99 LIH +A++ P+AVI V +GPYC IG V +G G KL+ V Sbjct: 9 LIHSTAIIDPSAVIASDVQIGPYCIIGPQVTIGAGTKLHSHVVVG--------------- 53 Query: 100 VVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSS- 158 G+T IG NN I A VG CQDLKYK G+E +L IGNNN IRE CS+HR + Sbjct: 54 -------GFTRIGQNNEIFQFASVGEVCQDLKYK-GEETWLEIGNNNLIREHCSLHRGTV 105 Query: 159 KPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFC 218 + + T IG +NL+M + HIAHDC +GD NIFANN +AGHV + D+ G S +HQFC Sbjct: 106 QDNALTKIGSHNLLMVNTHIAHDCIVGDHNIFANNVGVAGHVHIGDHVIVGGNSGIHQFC 165 Query: 219 HIGSFAFIGGGSVVSQDVPKYMMVAGERAELRGLNLEGLRRNGFTMSEMKSLRAAYRKIF 278 I S++ IGG S++ +DVP Y+M +G A G+N+EG+RR G++ + ++ LR AY+ IF Sbjct: 166 KIDSYSMIGGASLILKDVPAYVMASGNPAHAFGINIEGMRRKGWSKNTIQGLREAYKLIF 225 Query: 279 MSTETVSLSFEERLTELEQDQELYSVPAVSAMLQSIRDSFTESRRGICK 327 S T + ++ +E+ L SVP ++ DS +S RGI + Sbjct: 226 KSGLTSVQAIDQIKSEI-----LPSVPEAQLLI----DSLEQSERGIVR 265 >2JF2-A nrPDB Length = 264 Score = 285 bits (728), Expect = 2e-77, Method: Composition-based stats. Identities = 106/293 (36%), Positives = 154/293 (52%), Gaps = 34/293 (11%) Query: 36 DSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVL 95 D +HP+A+V A IG +GP+C +G V++G G L V Sbjct: 5 DKSAFVHPTAIVEEGASIGANAHIGPFCIVGPHVEIGEGTVLKSHVVV------------ 52 Query: 96 MTGAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIH 155 G+T IG +N I A +G QDLKY G+ + IG+ N IRE +IH Sbjct: 53 ----------NGHTKIGRDNEIYQFASIGEVNQDLKYA-GEPTRVEIGDRNRIRESVTIH 101 Query: 156 RSS-KPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVV 214 R + + T +G +NL+M + HIAHDC +G+R I ANN LAGHV V+D G + V Sbjct: 102 RGTVQGGGLTKVGSDNLLMINAHIAHDCTVGNRCILANNATLAGHVSVDDFAIIGGMTAV 161 Query: 215 HQFCHIGSFAFIGGGSVVSQDVPKYMMVAGERAELRGLNLEGLRRNGFTMSEMKSLRAAY 274 HQFC IG+ +GG S V+QDVP Y++ G A G+N+EGL+R GF+ + ++R AY Sbjct: 162 HQFCIIGAHVMVGGCSGVAQDVPPYVIAQGNHATPFGVNIEGLKRRGFSREAITAIRNAY 221 Query: 275 RKIFMSTETVSLSFEERLTELEQDQELYSVPAVSAMLQSIRDSFTESRRGICK 327 + I+ S +T +E E+ + E Y +++ D F S RG+ + Sbjct: 222 KLIYRSGKT----LDEVKPEIAELAETY------PEVKAFTDFFARSTRGLIR 264 Score = 42.2 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 18/72 (25%), Positives = 30/72 (41%) Query: 151 FCSIHRSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAG 210 I +S+ ++ + I + HI C +G T+L HVVV +T Sbjct: 1 GSMIDKSAFVHPTAIVEEGASIGANAHIGPFCIVGPHVEIGEGTVLKSHVVVNGHTKIGR 60 Query: 211 ASVVHQFCHIGS 222 + ++QF IG Sbjct: 61 DNEIYQFASIGE 72 >5JXX-A nrPDB Length = 257 Score = 277 bits (707), Expect = 6e-75, Method: Composition-based stats. Identities = 104/288 (36%), Positives = 161/288 (55%), Gaps = 34/288 (11%) Query: 41 IHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAV 100 IHP+A++ +A+I +GPYC +G + +++G VL + + Sbjct: 3 IHPTAIIDKSAMIADSAIIGPYCIVGKN------------------SQIGAHTVLRSHVI 44 Query: 101 VGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSS-K 159 +G+ T IG +N I A +G QDLKY G++ +L IG++N IRE C+IHR + + Sbjct: 45 IGE----NTKIGVHNDIYQFASIGENPQDLKYA-GEQTYLEIGDHNRIREACTIHRGTVQ 99 Query: 160 PSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFCH 219 T IG+ NL+M + HIAHDC +GD N+ ANN +AGH + ++ G S VHQFC Sbjct: 100 DRGITRIGNQNLLMVNVHIAHDCVVGDDNVLANNVGVAGHAHIGNHVIIGGQSGVHQFCR 159 Query: 220 IGSFAFIGGGSVVSQDVPKYMMVAGERAELRGLNLEGLRRNGFTMSEMKSLRAAYRKIFM 279 I ++ +GG S++ +DV Y+M +G A+ GLN EG+RR G++ +K+L AYR +F Sbjct: 160 IDDYSMVGGASLIVKDVAAYVMASGNPAKAHGLNKEGMRRKGWSKDTIKALDEAYRLVFR 219 Query: 280 STETVSLSFEERLTELEQDQELYSVPAVSAMLQSIRDSFTESRRGICK 327 S L +E L EL + E P + ++ DS S+RG+ + Sbjct: 220 SG----LLRDEALDELTKLVE--KEPKIQLLI----DSINNSKRGLVR 257 Score = 36.4 bits (82), Expect = 0.016, Method: Composition-based stats. Identities = 17/76 (22%), Positives = 32/76 (42%), Gaps = 12/76 (15%) Query: 147 EIREFCSIHRSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNT 206 I I +S+ +D +IG C + + +IG + + HV++ +NT Sbjct: 2 TIHPTAIIDKSAMIADSAIIGP------YCIVGKNSQIGAHTVLRS------HVIIGENT 49 Query: 207 HTAGASVVHQFCHIGS 222 + ++QF IG Sbjct: 50 KIGVHNDIYQFASIGE 65 >4EQY-A nrPDB Length = 283 Score = 275 bits (703), Expect = 2e-74, Method: Composition-based stats. Identities = 105/288 (36%), Positives = 164/288 (56%), Gaps = 30/288 (10%) Query: 41 IHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAV 100 IHP+A++ P A + + V VGPY +GS+V +G T +G V+ Sbjct: 25 IHPTAIIEPGAQLHETVEVGPYAIVGSNVTIG------------ARTTIGSHSVI----- 67 Query: 101 VGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSS-K 159 G+T IG +N IGH+A VG + QD+KYK + L IG+ N IREF +IH + + Sbjct: 68 -----EGHTTIGEDNRIGHYASVGGRPQDMKYKD-EPTRLVIGDRNTIREFTTIHTGTVQ 121 Query: 160 PSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFCH 219 + T +GD+N IM HI HDC++G + ++N +AGHV + D G S VHQ+ Sbjct: 122 DAGVTTLGDDNWIMAYVHIGHDCRVGSHVVLSSNAQMAGHVEIGDWAIVGGMSGVHQYVR 181 Query: 220 IGSFAFIGGGSVVSQDVPKYMMVAGERAELRGLNLEGLRRNGFTMSEMKSLRAAYRKIFM 279 IG+ + +GG S + QD+P +++ AG +AE G+N+EGLRR GF+ + +LR+AYR ++ Sbjct: 182 IGAHSMLGGASALVQDIPPFVIAAGNKAEPHGINVEGLRRRGFSPDAISALRSAYRILYK 241 Query: 280 STETVSLSFEERLTELEQDQELYSVPAVSAMLQSIRDSFTESRRGICK 327 + SLS EE +L + + + A ++++ D S+RGI + Sbjct: 242 N----SLSLEEAKVQLSELAQ--AGGDGDAAVKALVDFVESSQRGIIR 283 Score = 34.9 bits (78), Expect = 0.053, Method: Composition-based stats. Identities = 20/119 (16%), Positives = 42/119 (35%), Gaps = 4/119 (3%) Query: 160 PSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFCH 219 P + I +I + ++G I +N + + ++ G + + + Sbjct: 19 PGSMSRIHPTAIIEPGAQLHETVEVGPYAIVGSNVTIGARTTIGSHSVIEGHTTIGEDNR 78 Query: 220 IGSFAFIGGGSVVSQ-DVPKYMMVAGERAELRGLNLE---GLRRNGFTMSEMKSLRAAY 274 IG +A +GG + +V G+R +R ++ G T + AY Sbjct: 79 IGHYASVGGRPQDMKYKDEPTRLVIGDRNTIREFTTIHTGTVQDAGVTTLGDDNWIMAY 137 >5F42-A nrPDB Length = 280 Score = 273 bits (697), Expect = 8e-74, Method: Composition-based stats. Identities = 100/291 (34%), Positives = 142/291 (48%), Gaps = 35/291 (12%) Query: 40 LIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGA 99 +IH AVVH +A I +GP+C IG +V +G +L + N Sbjct: 1 MIHSLAVVHESAKIADSAIIGPFCVIGKNVVIGENTELKSHVTIGDN------------- 47 Query: 100 VVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSS- 158 IG NN I +A +G D YK GD + IG+NN IRE +IH + Sbjct: 48 ---------AVIGKNNRIFQYASIGDDPIDYTYKKGDFSQVVIGDNNIIRECATIHGGTA 98 Query: 159 KPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFC 218 K T +G+NN+IM HI HDCKIG N LAGHV ++D + VHQFC Sbjct: 99 KEIGVTSVGNNNIIMCYVHIGHDCKIGSYINLVNGVGLAGHVHIDDYAILSSNVGVHQFC 158 Query: 219 HIGSFAFIGGGSVVSQDVPKYMMVAGERA--ELRGLNLEGLRRNGFTMSEMKSLRAAYRK 276 +G AFI ++V +DVP Y+MV A G+N EGL+R GFT EMK ++ Y+ Sbjct: 159 RVGKHAFIAHAALVGKDVPPYLMVTAVNAGSTPCGINTEGLKRRGFTPEEMKKIKEVYKV 218 Query: 277 IFMSTETVSLSFEERLTELEQDQELYSVPAVSAMLQSIRDSFTESRRGICK 327 ++ + +F E + E+ ++ ++ L+ D SRRGI + Sbjct: 219 LYRKGLMMKEAF-EIIKEMAKEDKV---------LEPFVDVIGTSRRGILR 259 >3I3A-A nrPDB Length = 259 Score = 272 bits (694), Expect = 2e-73, Method: Composition-based stats. Identities = 91/289 (31%), Positives = 143/289 (49%), Gaps = 32/289 (11%) Query: 41 IHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAV 100 IHP+A++ P A + + V VGPY I +V + G + + +E+G+ GAV Sbjct: 3 IHPTAIIDPKAELHESVEVGPYSIIEGNVSIQEGTIIEGHVKICAGSEIGKFNRFHQGAV 62 Query: 101 VGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSSKP 160 +G V QDL + IG++N RE+ +IH+ +K Sbjct: 63 IG----------------------VMPQDLGFNQQLLTKTVIGDHNIFREYSNIHKGTKE 100 Query: 161 SDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFCHI 220 TVIG+ N MG+ H+ HDC +G+ NI + +LAGHV + + +G VHQFC + Sbjct: 101 DSPTVIGNKNYFMGNSHVGHDCILGNNNILTHGAVLAGHVTLGNFAFISGLVAVHQFCFV 160 Query: 221 GSFAFIGGGSVVSQDVPKYMMVAGERAELRGLNLEGLRRNGFTMSEMKSLRAAYRKIFMS 280 G ++ + G + V QDVP Y V G + + GLN G++R GF+ +++ AY+ I+ S Sbjct: 161 GDYSMVAGLAKVVQDVPPYSTVDGNPSTVVGLNSVGMKRAGFSPEVRNAIKHAYKVIYHS 220 Query: 281 TETVSLSFEERLTELEQDQELYSVPAVSAMLQSIRDSFTESRRGICKFR 329 +S + L ELE L + V +++ RD S RG+ R Sbjct: 221 G----ISTRKALDELEASGNL--IEQVKYIIKFFRD----SDRGVTNHR 259 >5DEP-A nrPDB Length = 258 Score = 269 bits (688), Expect = 1e-72, Method: Composition-based stats. Identities = 105/290 (36%), Positives = 152/290 (52%), Gaps = 34/290 (11%) Query: 39 VLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTG 98 LI P A++ P+A + V VGP+ +G+ V++G G + P + G T++G+ Sbjct: 2 SLIDPRAIIDPSARLAADVQVGPWSIVGAEVEIGEGTVIGPHVVLKGPTKIGKH------ 55 Query: 99 AVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSS 158 N I + VG DLKYK G+ L IG++N IRE +IHR + Sbjct: 56 ----------------NRIYQFSSVGEDTPDLKYK-GEPTRLVIGDHNVIREGVTIHRGT 98 Query: 159 -KPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQF 217 + +T IGD+NLIM HI HD IG+ I NNT LAGHV V+D +G ++VHQ+ Sbjct: 99 VQDRAETTIGDHNLIMAYAHIGHDSVIGNHCILVNNTALAGHVHVDDWAILSGYTLVHQY 158 Query: 218 CHIGSFAFIGGGSVVSQDVPKYMMVAGERAELRGLNLEGLRRNGFTMSEMKSLRAAYRKI 277 C IG+ +F G GS + +DVP Y+ V G AE R +N EG+RR GF+ + +LR AY+ + Sbjct: 159 CRIGAHSFSGMGSAIGKDVPAYVTVFGNPAEARSMNFEGMRRRGFSSEAIHALRRAYKVV 218 Query: 278 FMSTETVSLSFEERLTELEQDQELYSVPAVSAMLQSIRDSFTESRRGICK 327 + TV + E + P V+ RDS + RGI + Sbjct: 219 YRQGHTVEEALA------ELAESAAQFPEVAVF----RDSIQSATRGITR 258 >3R0S-A nrPDB Length = 266 Score = 260 bits (663), Expect = 7e-70, Method: Composition-based stats. Identities = 93/290 (32%), Positives = 140/290 (48%), Gaps = 36/290 (12%) Query: 41 IHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAV 100 IHPSAV+ A +G V + Y + K+GN + + + +T +G+ + + Sbjct: 7 IHPSAVIEEGAQLGDDVVIEAYAYVSKDAKIGNNVVIKQGARILSDTTIGDHSRVFS--- 63 Query: 101 VGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSSKP 160 +A+VG QD+ YK + + IG N IREF +I+ + Sbjct: 64 -------------------YAIVGDIPQDISYKEEQKSGVVIGKNATIREFATINSGTAK 104 Query: 161 SDK-TVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFCH 219 D T IGDN IM CHIAHDC +G+ I ANN LAGHV + D T G + +HQF Sbjct: 105 GDGFTRIGDNAFIMAYCHIAHDCLLGNNIILANNATLAGHVELGDFTVVGGLTPIHQFVK 164 Query: 220 IGSFAFIGGGSVVSQDVPKYMMVAGERAELRGLNLEGLRRNGFTMSEMKSLRAAYRKIFM 279 +G I G S +SQD+ + + G RA +R LNL G+RR F E+ L A++ +F Sbjct: 165 VGEGCMIAGASALSQDIVPFCLAEGNRASIRSLNLVGIRRR-FDKDEVDRLSRAFKTLFR 223 Query: 280 STETVSLSFEERLTELEQDQELYSVPAVSAMLQSIRDSFTESRRGICKFR 329 + +E L ++QE +V + + E++RGI +R Sbjct: 224 QGD-----LKENAKNLLENQESENVKKMCHFI-------LETKRGIPVYR 261 >4R36-A nrPDB Length = 275 Score = 255 bits (652), Expect = 2e-68, Method: Composition-based stats. Identities = 91/290 (31%), Positives = 152/290 (52%), Gaps = 33/290 (11%) Query: 38 EVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMT 97 +I P A +HP A IG+ V + P+ I +V +G+ K+ ++++ + +G + Sbjct: 19 SHMISPLAYIHPEAKIGENVEIAPFVYIDRNVVIGDNNKIMANANILYGSRIGNGNTIFP 78 Query: 98 GAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRS 157 GAV+G QDLK+K G+E IG+NN IRE +I+R Sbjct: 79 GAVIGA----------------------IPQDLKFK-GEESTAEIGDNNLIRENVTINRG 115 Query: 158 SKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQF 217 + +T++G+NNL+M H+AHD IG+ I N+T +AG ++++DN + ++HQF Sbjct: 116 TAAKGRTIVGNNNLLMEGVHVAHDALIGNGCIVGNSTKMAGEIIIDDNAIISANVLMHQF 175 Query: 218 CHIGSFAFIGGGSVVSQDVPKYMMVAGERAELRGLNLEGLRRNGFTMSEMKSLRAAYRKI 277 C +G + I GG S+D+P Y++ E G+N+ GLRR GF+ ++++ AYR I Sbjct: 176 CRVGGYVMIQGGCRFSKDIPPYIIAGREPIAYSGINIIGLRRRGFSNEIIENIHNAYRII 235 Query: 278 FMSTETVSLSFEERLTELEQDQELYSVPAVSAMLQSIRDSFTESRRGICK 327 + S L+ + LT++E + S ++ I D S RGI + Sbjct: 236 YQSG----LNTSDALTKVEAEVP------ASPEIEYIVDFIRNSERGIIR 275 Score = 27.9 bits (60), Expect = 7.1, Method: Composition-based stats. Identities = 9/40 (22%), Positives = 19/40 (47%) Query: 37 SEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCK 76 + + ++ NA+I V + +C +G V + GC+ Sbjct: 150 NSTKMAGEIIIDDNAIISANVLMHQFCRVGGYVMIQGGCR 189 >1J2Z-A nrPDB Length = 270 Score = 253 bits (646), Expect = 7e-68, Method: Composition-based stats. Identities = 100/286 (34%), Positives = 143/286 (50%), Gaps = 35/286 (12%) Query: 41 IHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAV 100 I +A++ P A I KGV +G +C IG VKL G KL+ + + Sbjct: 4 IAKTAIISPKAEINKGVEIGEFCVIGDGVKLDEGVKLHNNVTL----------------- 46 Query: 101 VGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSSKP 160 G+TF+G N I AV+G + QDLKYK G+ L IG +N IREFC I+ ++ Sbjct: 47 -----QGHTFVGKNTEIFPFAVLGTQPQDLKYK-GEYSELIIGEDNLIREFCMINPGTEG 100 Query: 161 S-DKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFCH 219 KT+IGD NL+M H+AHDC IG I AN LAGH+ + D + G + +HQF Sbjct: 101 GIKKTLIGDKNLLMAYVHVAHDCVIGSHCILANGVTLAGHIEIGDYVNIGGLTAIHQFVR 160 Query: 220 IGSFAFIGGGSVVSQDVPKYMMVAGERAELRGLNLEGLRRNGFTMSEMKSLRAAYRKIFM 279 I I G S + +DVP Y V G RA +RGLN +R+ ++ + A Y+++F Sbjct: 161 IAKGCMIAGKSALGKDVPPYCTVEGNRAFIRGLNRHRMRQL-LESKDIDFIYALYKRLFR 219 Query: 280 STETVSLSFEERLTELEQDQELYSVPAVSAMLQSIRDSFTESRRGI 325 ++ S ELE+ V + + + ES RG+ Sbjct: 220 PIPSLRES---AKLELEEHANNPFVKEICSFI-------LESSRGV 255 Score = 31.4 bits (69), Expect = 0.61, Method: Composition-based stats. Identities = 10/85 (11%), Positives = 33/85 (38%), Gaps = 6/85 (7%) Query: 36 DSEVLIHPSAVVHPNAVIGKGVSVGPYCT------IGSSVKLGNGCKLYPSSHVFGNTEL 89 + LI ++ + +G +C + +++G+ + + + + Sbjct: 102 IKKTLIGDKNLLMAYVHVAHDCVIGSHCILANGVTLAGHIEIGDYVNIGGLTAIHQFVRI 161 Query: 90 GESCVLMTGAVVGDELPGYTFIGCN 114 + C++ + +G ++P Y + N Sbjct: 162 AKGCMIAGKSALGKDVPPYCTVEGN 186 >4IHG-A nrPDB Length = 348 Score = 185 bits (468), Expect = 3e-47, Method: Composition-based stats. Identities = 66/266 (24%), Positives = 115/266 (43%), Gaps = 43/266 (16%) Query: 37 SEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLM 96 + V I +AV+ +G V +G C +G + K+G G +L+ + ++ ++G++C++ Sbjct: 121 NNVSIGANAVIESGVELGDNVIIGAGCFVGKNSKIGAGSRLWANVTIYHEIQIGQNCLIQ 180 Query: 97 TGAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHR 156 +G VVG + GY N G+ K + IG+ EI +I R Sbjct: 181 SGTVVGADGFGYA-----NDRGNWV-----------KIPQIGRVIIGDRVEIGACTTIDR 224 Query: 157 SSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQ 216 + D T+IG+ +I C IAH+ IG DNT AG ++ Sbjct: 225 GAL--DDTIIGNGVIIDNQCQIAHNVVIG------------------DNTAVAGGVIMAG 264 Query: 217 FCHIGSFAFIGGGSVVS--QDVPKYMMVAGERAELRGLNLEGLRRNGFTMSEMKSLRAAY 274 IG + IGG SV++ ++ + V G +R + G+ +G + K R Sbjct: 265 SLKIGRYCMIGGASVINGHMEICDKVTVTGMGMVMRPITEPGVYSSGIPLQPNKVWRKT- 323 Query: 275 RKIFMSTETVSLSFEERLTELEQDQE 300 + M+ + +S +RL LE+ Sbjct: 324 AALVMNIDDMS----KRLKSLERKVN 345 Score = 42.6 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 18/108 (16%), Positives = 37/108 (34%) Query: 145 NNEIREFCSIHRSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVED 204 + + +I S+ +G+N I + I ++GD I + + + Sbjct: 98 DTTPQPAQNIAPSAVIDATAKLGNNVSIGANAVIESGVELGDNVIIGAGCFVGKNSKIGA 157 Query: 205 NTHTAGASVVHQFCHIGSFAFIGGGSVVSQDVPKYMMVAGERAELRGL 252 + ++ IG I G+VV D Y G ++ + Sbjct: 158 GSRLWANVTIYHEIQIGQNCLIQSGTVVGADGFGYANDRGNWVKIPQI 205 >4E79-A nrPDB Length = 357 Score = 162 bits (409), Expect = 2e-40, Method: Composition-based stats. Identities = 58/271 (21%), Positives = 105/271 (38%), Gaps = 20/271 (7%) Query: 33 DSRDSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGES 92 D + S I +A +HP+AVI + +G Y IG + +G+ + + + N E+G+ Sbjct: 97 DKKISSTGIESTARIHPSAVISETAYIGHYVVIGENCVVGDNTVIQSHTKLDDNVEVGKD 156 Query: 93 CVLMTGAVV--GDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIRE 150 C + + + +L I + +IG Q ++ + IGN+ I Sbjct: 157 CFIDSYVTITGSSKLRDRVRIHSSTVIGGEGFGFAPYQGKWHRIAQLGSVLIGNDVRIGS 216 Query: 151 FCSIHRSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAG 210 CSI R + D T++ D +I IAH+ IG A +AG + N AG Sbjct: 217 NCSIDRGAL--DNTILEDGVIIDNLVQIAHNVHIGSNTAIAAKCGIAGSTKIGKNCILAG 274 Query: 211 ASVVHQFCHIGSFAFIGGGSVVSQDVPKYMMVAGERAELRGLNLEGLRRNGFTMSEMKSL 270 A V I + G S+V++++ + G +G + E Sbjct: 275 ACGVAGHLSIADNVTLTGMSMVTKNI----------------SEAGTYSSGTGLFENNHW 318 Query: 271 RAAYRKIFMSTETVSLSFEERLTELEQDQEL 301 + ++ + +RL ++ E Sbjct: 319 KKTIVRLRQLADVPLTQITKRLDHIQAQIES 349 >3PMO-A nrPDB Length = 372 Score = 158 bits (398), Expect = 4e-39, Method: Composition-based stats. Identities = 56/264 (21%), Positives = 99/264 (37%), Gaps = 39/264 (14%) Query: 36 DSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVL 95 D + AV+ A IG GVS+G +C IG+ +G G L P ++ + +G + Sbjct: 135 DPSASVGAYAVIESGARIGAGVSIGAHCVIGARSVIGEGGWLAPRVTLYHDVTIGARVSI 194 Query: 96 MTGAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIH 155 +GAV+G E G+ F + A +G + IG++ EI +I Sbjct: 195 QSGAVIGGE--GFGFANEKGVWQKIAQIG--------------GVTIGDDVEIGANTTID 238 Query: 156 RSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVH 215 R + T+IG+ + IAH+ +IGD A ++G Sbjct: 239 RGAL--SDTLIGNGVKLDNQIMIAHNVQIGDHTAMAACVGISG----------------- 279 Query: 216 QFCHIGSFAFIGGGSVVSQ--DVPKYMMVAGERAELRGLNLEGLRRNGFTMSEMKSLRAA 273 IG + GG + ++ + V G R + G +G M + + Sbjct: 280 -SAKIGRHCMLAGGVGLVGHIEICDNVFVTGMTMVTRSITEPGSYSSGTAMQPAAEWKKS 338 Query: 274 YRKIFMSTETVSLSFEERLTELEQ 297 +I + ++ ++ L Sbjct: 339 AARI-RQLDDMARRLQQLEKRLAA 361 >2IUA-A nrPDB Length = 374 Score = 142 bits (357), Expect = 2e-34, Method: Composition-based stats. Identities = 46/219 (21%), Positives = 82/219 (37%), Gaps = 17/219 (7%) Query: 40 LIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGA 99 IHP+AV+HP A+I V + PY + +G+ C + S + + +GE + Sbjct: 126 GIHPTAVIHPTAIIEDHVCIEPYAVVCQHAHVGSACHIGSGSVIGAYSTVGEHSYIHPRV 185 Query: 100 VVGDELPGYTFIGCNNIIGHHAVVG---------VKCQDLKYKHGDECFLCIGNNNEIRE 150 V+ + + IG II AV+G Q KH + I ++ EI Sbjct: 186 VIRERVS----IGKRVIIQPGAVIGSCGFGYVTSAFGQHKHLKH--LGKVIIEDDVEIGA 239 Query: 151 FCSIHRSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAG 210 +I R G I IAH ++G ++ +AG + ++ G Sbjct: 240 NTTIDRGRFKHSVVREGSK--IDNLVQIAHQVEVGQHSMIVAQAGIAGSTKIGNHVIIGG 297 Query: 211 ASVVHQFCHIGSFAFIGGGSVVSQDVPKYMMVAGERAEL 249 + + I + + V++ + + G A Sbjct: 298 QAGITGHICIADHVIMMAQTGVTKSITSPGIYGGAPARP 336 >1XHD-A nrPDB Length = 173 Score = 96.9 bits (239), Expect = 1e-20, Method: Composition-based stats. Identities = 42/178 (23%), Positives = 71/178 (39%), Gaps = 49/178 (27%) Query: 104 ELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSSK---- 159 + G ++G + I + V+ GD IG+ +++ C++H+S + Sbjct: 26 TITGDVYVGEESSIWFNTVI----------RGDVSPTIIGDRVNVQDQCTLHQSPQYPLI 75 Query: 160 PSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFCH 219 D +G + +I+ SCHI D IG S++ Sbjct: 76 LEDDVTVG-HQVILHSCHIKKDALIG------------------------MGSIILDGAE 110 Query: 220 IGSFAFIGGGSVVSQ--DVPKYMMVAGERAE-LRGLNLEGLRRNGFTMSEMKSLRAAY 274 IG AFIG GS+VSQ +P + G A+ +R L E + +M+ +R Y Sbjct: 111 IGEGAFIGAGSLVSQGKKIPPNTLAFGRPAKVIRELTAEDRK-------DMERIRTQY 161 Score = 31.8 bits (70), Expect = 0.42, Method: Composition-based stats. Identities = 10/44 (22%), Positives = 20/44 (45%) Query: 38 EVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSS 81 I A++ ++I G +G IG+ + G K+ P++ Sbjct: 90 SCHIKKDALIGMGSIILDGAEIGEGAFIGAGSLVSQGKKIPPNT 133 Score = 30.6 bits (67), Expect = 0.93, Method: Composition-based stats. Identities = 8/39 (20%), Positives = 16/39 (41%) Query: 37 SEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGC 75 + LI +++ A IG+G +G + K+ Sbjct: 95 KDALIGMGSIILDGAEIGEGAFIGAGSLVSQGKKIPPNT 133 Score = 29.9 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 9/67 (13%), Positives = 21/67 (31%), Gaps = 5/67 (7%) Query: 52 VIGKGVSVGPY-----CTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVVGDELP 106 ++ V+VG C I +G G + + + +G ++ G + Sbjct: 75 ILEDDVTVGHQVILHSCHIKKDALIGMGSIILDGAEIGEGAFIGAGSLVSQGKKIPPNTL 134 Query: 107 GYTFIGC 113 + Sbjct: 135 AFGRPAK 141 >4MFG-A nrPDB Length = 168 Score = 95.0 bits (234), Expect = 4e-20, Method: Composition-based stats. Identities = 39/159 (24%), Positives = 68/159 (42%), Gaps = 36/159 (22%) Query: 103 DELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSSKPSD 162 ++ G IG ++ I ++AVV GDE + IG N I++ +H ++ Sbjct: 25 ADVIGNVKIGKDSSIWYNAVV----------RGDEGPITIGENTNIQDCSIVHGDTE--- 71 Query: 163 KTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFCHIGS 222 T+IG NN+ +G I H CKI DN S++ IG Sbjct: 72 -TIIG-NNVTVGHRSIVHGCKIS------------------DNVLIGMGSIILDNAEIGE 111 Query: 223 FAFIGGGSVV--SQDVPKYMMVAGERAE-LRGLNLEGLR 258 + IG G+++ ++ P +++ G + +R L E + Sbjct: 112 YTLIGAGTLITSNKKFPPGVLIMGSPGKVVRELTEEDKK 150 Score = 55.7 bits (132), Expect = 3e-08, Method: Composition-based stats. Identities = 34/139 (24%), Positives = 54/139 (38%), Gaps = 13/139 (9%) Query: 64 TIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVVGDELPGYTFIGCNNIIGHHAVV 123 + + + S+ V GN ++G+ + AVV + G IG N I Sbjct: 8 YLEDKPLIDESVFVAKSADVIGNVKIGKDSSIWYNAVVRGD-EGPITIGENTNI------ 60 Query: 124 GVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSSKPSDKTVIGDNNLIMGSCHIAHDCK 183 QD HGD IGNN + +H K SD +IG ++I+ + I Sbjct: 61 ----QDCSIVHGD-TETIIGNNVTVGHRSIVH-GCKISDNVLIGMGSIILDNAEIGEYTL 114 Query: 184 IGDRNIFANNTLLAGHVVV 202 IG + +N V++ Sbjct: 115 IGAGTLITSNKKFPPGVLI 133 Score = 36.4 bits (82), Expect = 0.016, Method: Composition-based stats. Identities = 16/94 (17%), Positives = 33/94 (35%), Gaps = 4/94 (4%) Query: 37 SEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLM 96 + V + ++VH I V +G I + ++G + + + N + ++M Sbjct: 76 NNVTVGHRSIVH-GCKISDNVLIGMGSIILDNAEIGEYTLIGAGTLITSNKKFPPGVLIM 134 Query: 97 --TGAVVGD-ELPGYTFIGCNNIIGHHAVVGVKC 127 G VV + +I + A K Sbjct: 135 GSPGKVVRELTEEDKKYIDESYEWYLEAAQNQKY 168 >4M9C-A nrPDB Length = 216 Score = 93.8 bits (231), Expect = 1e-19, Method: Composition-based stats. Identities = 32/119 (26%), Positives = 51/119 (42%), Gaps = 5/119 (4%) Query: 136 DECFLCIGNNNEIREFCSIHRSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTL 195 I + EI E + + + IG ++AHDC IGD FA Sbjct: 94 QSTNTVILDEVEIGEGSLLCPFTCLTSNIKIGKFFHANIYSYVAHDCVIGDYVTFAPGAK 153 Query: 196 LAGHVVVEDNTHTAGASVVHQFCH-----IGSFAFIGGGSVVSQDVPKYMMVAGERAEL 249 G++ +ED+ + +V+ Q IG A +G G+VV++ VP + V G A + Sbjct: 154 CNGNIHIEDHAYIGTGAVIKQGTPDKPLIIGKGAIVGMGAVVTKSVPAGVTVVGNPARI 212 Score = 41.8 bits (96), Expect = 4e-04, Method: Composition-based stats. Identities = 33/138 (23%), Positives = 51/138 (36%), Gaps = 4/138 (2%) Query: 8 REKLLSPLVSSTIRRL---SSSLSYSREDSRDSEVLIHPSAVVHPNAVIGKGVSVGPYCT 64 REKL+S L ++ L S++ E L+ P + N IGK Y Sbjct: 76 REKLVSLLEKDGVQHLAVQSTNTVILDEVEIGEGSLLCPFTCLTSNIKIGKFFHANIYSY 135 Query: 65 IGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVVGDELPG-YTFIGCNNIIGHHAVV 123 + +G+ P + GN + + + TGAV+ P IG I+G AVV Sbjct: 136 VAHDCVIGDYVTFAPGAKCNGNIHIEDHAYIGTGAVIKQGTPDKPLIIGKGAIVGMGAVV 195 Query: 124 GVKCQDLKYKHGDECFLC 141 G+ + Sbjct: 196 TKSVPAGVTVVGNPARIL 213 >1HM0-A nrPDB Length = 468 Score = 76.5 bits (186), Expect = 2e-14, Method: Composition-based stats. Identities = 39/213 (18%), Positives = 79/213 (37%), Gaps = 24/213 (11%) Query: 39 VLIHPSA-VVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMT 97 ++P A + + I V + + K+G L ++V ++ +G V+ Sbjct: 262 SFVNPEATYIDIDVEIAPEVQIEANVILKGQTKIGAETVLTNGTYVV-DSTIGAGAVITN 320 Query: 98 GAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRS 157 + + +G I ++ +G + + IGN E++ SI + Sbjct: 321 SMIEESSVADGVTVGPYAHIRPNSSLGAQ-------------VHIGNFVEVK-GSSIGEN 366 Query: 158 SKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGH-VVVEDNTHTAGASVVHQ 216 +K T IG+ C + + G I N + V+ DN S + Sbjct: 367 TKAGHLTYIGN-------CEVGSNVNFGAGTITVNYDGKNKYKTVIGDNVFVGSNSTIIA 419 Query: 217 FCHIGSFAFIGGGSVVSQDVPKYMMVAGERAEL 249 +G + +G GS +++DVP + G ++ Sbjct: 420 PVELGDNSLVGAGSTITKDVPADAIAIGRGRQI 452 Score = 51.8 bits (122), Expect = 4e-07, Method: Composition-based stats. Identities = 26/140 (18%), Positives = 54/140 (38%), Gaps = 13/140 (9%) Query: 33 DSRDSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGES 92 DS + ++++ ++ + GV+VGPY I + LG + V + +GE+ Sbjct: 309 DSTIGAGAVITNSMIEESS-VADGVTVGPYAHIRPNSSLGAQVHIGNFVEV-KGSSIGEN 366 Query: 93 CVLMTGAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFC 152 +G N +G + G + Y ++ IG+N + Sbjct: 367 TKAGHLTYIG-----------NCEVGSNVNFGAGTITVNYDGKNKYKTVIGDNVFVGSNS 415 Query: 153 SIHRSSKPSDKTVIGDNNLI 172 +I + D +++G + I Sbjct: 416 TIIAPVELGDNSLVGAGSTI 435 Score = 50.3 bits (118), Expect = 1e-06, Method: Composition-based stats. Identities = 30/145 (20%), Positives = 53/145 (36%), Gaps = 13/145 (8%) Query: 28 SYSREDSRDSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNT 87 S E S V + P A + PN+ +G V +G + + +G K GN Sbjct: 321 SMIEESSVADGVTVGPYAHIRPNSSLGAQVHIGNFVEV-KGSSIGENTK-AGHLTYIGNC 378 Query: 88 ELGESCVLMTGAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNE 147 E+G + G + + +IG + VG + + +G+N+ Sbjct: 379 EVGSNVNFGAGTI---TVNYDGKNKYKTVIGDNVFVGSNSTII-------APVELGDNSL 428 Query: 148 IREFCSIHRSSKPSDKTVIGDNNLI 172 + +I + P+D IG I Sbjct: 429 VGAGSTITKDV-PADAIAIGRGRQI 452 >3NZ2-A nrPDB Length = 195 Score = 74.2 bits (180), Expect = 8e-14, Method: Composition-based stats. Identities = 32/127 (25%), Positives = 52/127 (40%), Gaps = 8/127 (6%) Query: 140 LCIGNNNEIREFCSIHRSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGH 199 + IG++ I + IGD+ LI S D + Sbjct: 77 IRIGDHTFINMNVVM----LDGAPITIGDHVLIGPSTQFYTASHSLDYRRRQAWETICKP 132 Query: 200 VVVEDNTHTAGASVVHQFCHIGSFAFIGGGSVVSQDVPKYMMVAGERAELRGLNLEGLRR 259 +V+ED+ G V++Q IG+ + + SVV+QDVP +V G A + L L+ Sbjct: 133 IVIEDDVWIGGNVVINQGVTIGARSVVAANSVVNQDVPPDTLVGGTPARI----LRSLKD 188 Query: 260 NGFTMSE 266 +M+E Sbjct: 189 PAESMAE 195 Score = 29.1 bits (63), Expect = 2.9, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 28/77 (36%), Gaps = 11/77 (14%) Query: 11 LLSPLVSSTIRRLSSSLSYSREDSRDSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVK 70 L+ P S+ S SL Y R + ++ + VI V +G I V Sbjct: 104 LIGP--STQFYTASHSLDYRRRQAWET---------ICKPIVIEDDVWIGGNVVINQGVT 152 Query: 71 LGNGCKLYPSSHVFGNT 87 +G + +S V + Sbjct: 153 IGARSVVAANSVVNQDV 169 >4DCL-A nrPDB Length = 207 Score = 71.9 bits (174), Expect = 4e-13, Method: Composition-based stats. Identities = 28/129 (21%), Positives = 46/129 (35%), Gaps = 4/129 (3%) Query: 140 LCIGNNNEIREFCSIHRSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGH 199 + +G N + C + IGDN I +C + + AG Sbjct: 75 VKLGKNVYVNTNCYF----MDGGQITIGDNVFIGPNCGFYTATHPLNFHHRNEGFEKAGP 130 Query: 200 VVVEDNTHTAGASVVHQFCHIGSFAFIGGGSVVSQDVPKYMMVAGERAELRGLNLEGLRR 259 + + NT G V IG + IG GSVV++D+P + + G ++ L Sbjct: 131 IHIGSNTWFGGHVAVLPGVTIGEGSVIGAGSVVTKDIPPHSLAVGNPCKVVRKIDNDLPS 190 Query: 260 NGFTMSEMK 268 +K Sbjct: 191 ETLNDETIK 199 Score = 41.4 bits (95), Expect = 6e-04, Method: Composition-based stats. Identities = 23/126 (18%), Positives = 43/126 (34%), Gaps = 24/126 (19%) Query: 8 REKLLSPLVSSTIRRLSSSL----SYSREDSRDSEVLIHPSAVVHPNAVI--GKGVSVGP 61 R+ L+ L +T +S S+ Y V ++ + I G V +GP Sbjct: 46 RKVLIDALFQTTTDNVSISIPFDTDYGWNVKLGKNVYVNTNCYFMDGGQITIGDNVFIGP 105 Query: 62 YC--TIGSS----------------VKLGNGCKLYPSSHVFGNTELGESCVLMTGAVVGD 103 C + + +G+ V +GE V+ G+VV Sbjct: 106 NCGFYTATHPLNFHHRNEGFEKAGPIHIGSNTWFGGHVAVLPGVTIGEGSVIGAGSVVTK 165 Query: 104 ELPGYT 109 ++P ++ Sbjct: 166 DIPPHS 171 >3MQG-A nrPDB Length = 192 Score = 68.4 bits (165), Expect = 4e-12, Method: Composition-based stats. Identities = 40/213 (18%), Positives = 66/213 (30%), Gaps = 62/213 (29%) Query: 39 VLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTG 98 IHP+A+V A IG + + I ++G GC L + V +G + Sbjct: 4 ATIHPTAIVDEGARIGAHSRIWHWVHICGGAEIGEGCSLGQNVFVGNRVRIGNRVKIQNN 63 Query: 99 AVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSS 158 + F+ + G V N +I R S Sbjct: 64 V----SVYDNVFLEDDVFCGPSMVFT---------------------NVYNPRAAIERKS 98 Query: 159 KPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFC 218 + D T++ + +C + IG Sbjct: 99 EYRD-TIVRQGATLGANCTVVCGATIG--------------------------------- 124 Query: 219 HIGSFAFIGGGSVVSQDVPKYMMVAGERAELRG 251 +AF+G G+VV++DVP + +V G A G Sbjct: 125 ---RYAFVGAGAVVNKDVPDFALVVGVPARQIG 154 >5VMK-A nrPDB Length = 462 Score = 67.2 bits (162), Expect = 9e-12, Method: Composition-based stats. Identities = 47/217 (21%), Positives = 79/217 (36%), Gaps = 40/217 (18%) Query: 38 EVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMT 97 +V I + ++ N +G V +G C + + + G K+ S + Sbjct: 276 DVRIDVNVIIEGNCELGDFVEIGAGCIL-KNTTIAAGTKVQAYS-------------VFD 321 Query: 98 GAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRS 157 GAVVG+ T IG + A + + IGN E++ +I Sbjct: 322 GAVVGE----NTQIGPFARLRPGAKLA-------------NEVHIGNFVEVK-NTTIGLG 363 Query: 158 SKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGH-VVVEDNTHTAGASVVHQ 216 SK + T +GD I + IG I N H + D S + Sbjct: 364 SKANHFTYLGD-------AEIGAESNIGAGTITCNYDGANKHKTTIGDAVFIGSNSSLVA 416 Query: 217 FCHIGSFAFIGGGSVVSQDVPKYMMVAGERAELRGLN 253 IG+ A +G GSV+++DV + + ++ N Sbjct: 417 PVTIGNGATVGAGSVITKDVAEQSLSFERAQQISKAN 453 Score = 34.9 bits (78), Expect = 0.047, Method: Composition-based stats. Identities = 35/231 (15%), Positives = 70/231 (30%), Gaps = 11/231 (4%) Query: 31 REDSRDSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELG 90 R+D + ++ H A I + ++ G YC + + ++ Sbjct: 149 RQDGKIQAIVEHKDAT-EAQRQIQE-INTGIYCVSNAKLHEWLPKLSNENAQGEYYLTDI 206 Query: 91 ESCVLMTGAVVGDELPGYTF-IGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIR 149 + + G + P F + N A + + Q + K + + + Sbjct: 207 VAMAVADGLEIASIQPELAFEVEGVNDRLQLAALEREFQKQQAKELMQQGVTFADPARF- 265 Query: 150 EFCSIHRSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAG----HVVVEDN 205 + + K I N +I G+C + +IG I N T+ AG V D Sbjct: 266 ---DLRGTVKVGHDVRIDVNVIIEGNCELGDFVEIGAGCILKNTTIAAGTKVQAYSVFDG 322 Query: 206 THTAGASVVHQFCHIGSFAFIGGGSVVSQDVPKYMMVAGERAELRGLNLEG 256 + + F + A + + V G ++ G Sbjct: 323 AVVGENTQIGPFARLRPGAKLANEVHIGNFVEVKNTTIGLGSKANHFTYLG 373 >1OCX-A nrPDB Length = 182 Score = 66.5 bits (160), Expect = 1e-11, Method: Composition-based stats. Identities = 23/87 (26%), Positives = 38/87 (43%) Query: 163 KTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFCHIGS 222 IGDN ++ HI D + L V + +N G +V++ IG Sbjct: 92 PIRIGDNCMLAPGVHIYTATHPIDPVARNSGAELGKPVTIGNNVWIGGRAVINPGVTIGD 151 Query: 223 FAFIGGGSVVSQDVPKYMMVAGERAEL 249 + G+VV++DVP ++V G A + Sbjct: 152 NVVVASGAVVTKDVPDNVVVGGNPARI 178 Score = 42.2 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 15/77 (19%), Positives = 33/77 (42%) Query: 38 EVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMT 97 ++ P ++ V+ +G V +GN + + + +G++ V+ + Sbjct: 98 NCMLAPGVHIYTATHPIDPVARNSGAELGKPVTIGNNVWIGGRAVINPGVTIGDNVVVAS 157 Query: 98 GAVVGDELPGYTFIGCN 114 GAVV ++P +G N Sbjct: 158 GAVVTKDVPDNVVVGGN 174 Score = 34.1 bits (76), Expect = 0.092, Method: Composition-based stats. Identities = 11/42 (26%), Positives = 17/42 (40%), Gaps = 4/42 (9%) Query: 37 SEVLIHPSAVVHPNAVIGKGVSVGPYCTIGS----SVKLGNG 74 + V I AV++P IG V V + +V +G Sbjct: 133 NNVWIGGRAVINPGVTIGDNVVVASGAVVTKDVPDNVVVGGN 174 Score = 27.6 bits (59), Expect = 7.5, Method: Composition-based stats. Identities = 11/48 (22%), Positives = 20/48 (41%) Query: 34 SRDSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSS 81 +R+S + + N IG + P TIG +V + +G + Sbjct: 118 ARNSGAELGKPVTIGNNVWIGGRAVINPGVTIGDNVVVASGAVVTKDV 165 >4N6B-A nrPDB Length = 286 Score = 66.1 bits (159), Expect = 2e-11, Method: Composition-based stats. Identities = 27/125 (21%), Positives = 40/125 (32%), Gaps = 6/125 (4%) Query: 146 NEIREFCSIHRSSKPSDKT--VIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVE 203 +I I + T V+G+ +I + I H +G H + Sbjct: 153 VDIHPAARIGKGILFDHATGVVVGETAVIGNNVSILHHVTLGG----TGKVGGDRHPKIG 208 Query: 204 DNTHTAGASVVHQFCHIGSFAFIGGGSVVSQDVPKYMMVAGERAELRGLNLEGLRRNGFT 263 D + + IG A +G GSVV DVP G A L G + + Sbjct: 209 DGVLIGAGATILGNIKIGEGAKVGAGSVVLIDVPPRTTAVGNPARLVGGKEKPSKHEDVP 268 Query: 264 MSEMK 268 M Sbjct: 269 GESMD 273 Score = 48.0 bits (112), Expect = 5e-06, Method: Composition-based stats. Identities = 23/104 (22%), Positives = 40/104 (38%), Gaps = 6/104 (5%) Query: 47 VHPNAVIGKGVSVGP--YCTIGSSVKLGNGCKLYPSSHVFGNTELG--ESCVLMTGAVV- 101 +HP A IGKG+ +G + +GN + + G ++G + G ++ Sbjct: 155 IHPAARIGKGILFDHATGVVVGETAVIGNNVSILHHVTLGGTGKVGGDRHPKIGDGVLIG 214 Query: 102 -GDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGN 144 G + G IG +G +VV + G+ L G Sbjct: 215 AGATILGNIKIGEGAKVGAGSVVLIDVPPRTTAVGNPARLVGGK 258 Score = 43.7 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 9/79 (11%) Query: 42 HPSAVV-HPNAVIGKGVSVGPYCTIG--------SSVKLGNGCKLYPSSHVFGNTELGES 92 H + VV AVIG VS+ + T+G K+G+G + + + GN ++GE Sbjct: 169 HATGVVVGETAVIGNNVSILHHVTLGGTGKVGGDRHPKIGDGVLIGAGATILGNIKIGEG 228 Query: 93 CVLMTGAVVGDELPGYTFI 111 + G+VV ++P T Sbjct: 229 AKVGAGSVVLIDVPPRTTA 247 >1KRR-A nrPDB Length = 203 Score = 66.1 bits (159), Expect = 2e-11, Method: Composition-based stats. Identities = 25/117 (21%), Positives = 49/117 (41%), Gaps = 3/117 (2%) Query: 143 GNNNEIREF--CSIHRSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHV 200 G+N I + + + IGDN LI + ++ + N + + + Sbjct: 73 GSNIHIGRNFYANFNLTIVDDYTVTIGDNVLIAPNVTLSVTGHPVHHELRKNGEMYSFPI 132 Query: 201 VVEDNTHTAGASVVHQFCHIGSFAFIGGGSVVSQDVPKYMMVAGERAE-LRGLNLEG 256 + +N V++ IG + IG GS+V++D+P ++ AG +R +N Sbjct: 133 TIGNNVWIGSHVVINPGVTIGDNSVIGAGSIVTKDIPPNVVAAGVPCRVIREINDRD 189 Score = 36.4 bits (82), Expect = 0.016, Method: Composition-based stats. Identities = 13/84 (15%), Positives = 29/84 (34%), Gaps = 18/84 (21%) Query: 44 SAVVHPNAVIGKGVSVGPYCTIGSS------------------VKLGNGCKLYPSSHVFG 85 + V IG V + P T+ + + +GN + + Sbjct: 89 TIVDDYTVTIGDNVLIAPNVTLSVTGHPVHHELRKNGEMYSFPITIGNNVWIGSHVVINP 148 Query: 86 NTELGESCVLMTGAVVGDELPGYT 109 +G++ V+ G++V ++P Sbjct: 149 GVTIGDNSVIGAGSIVTKDIPPNV 172 Score = 32.6 bits (72), Expect = 0.28, Method: Composition-based stats. Identities = 7/33 (21%), Positives = 13/33 (39%) Query: 37 SEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSV 69 + V I V++P IG +G + + Sbjct: 136 NNVWIGSHVVINPGVTIGDNSVIGAGSIVTKDI 168 >4G3P-A nrPDB Length = 501 Score = 65.3 bits (157), Expect = 4e-11, Method: Composition-based stats. Identities = 46/205 (22%), Positives = 75/205 (36%), Gaps = 15/205 (7%) Query: 65 IGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAV-----VGDELPGYTFIGCNNIIGH 119 I V +G ++P + + G T++G CV+ VGD G ++ IG Sbjct: 280 IDVDVTIGRDTVIHPGTQLLGRTQIGGRCVVGPDTTLTDVAVGDGASVVRTHGSSSSIGD 339 Query: 120 HAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSSKPSDKTVIGDNNLIMGSCHIA 179 A VG L+ +G E++ +I +K T +GD I Sbjct: 340 GAAVG-PFTYLRPGTALGADGKLGAFVEVK-NSTIGTGTKVPHLTYVGD-------ADIG 390 Query: 180 HDCKIGDRNIFANNTLLAGH-VVVEDNTHTAGASVVHQFCHIGSFAFIGGGSVVSQDVPK 238 IG ++F N + V + T ++ IG A+ G G+VV +DVP Sbjct: 391 EYSNIGASSVFVNYDGTSKRRTTVGSHVRTGSDTMFVAPVTIGDGAYTGAGTVVREDVPP 450 Query: 239 YMMVAGERAELRGLNLEGLRRNGFT 263 + + N +R G Sbjct: 451 GALAVSAGPQRNIENWVQRKRPGSP 475 Score = 43.0 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 28/144 (19%), Positives = 51/144 (35%), Gaps = 18/144 (12%) Query: 49 PNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVVGDELPGY 108 ++ IG G +VGP+ + LG KL V N+ +G G ++P Sbjct: 333 SSSSIGDGAAVGPFTYLRPGTALGADGKLGAFVEV-KNSTIGT----------GTKVPHL 381 Query: 109 TFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSSKPSDKTVIGD 168 T++G + IG ++ +G + Y + +G++ + IGD Sbjct: 382 TYVG-DADIGEYSNIGASSVFVNYDGTSKRRTTVGSHVRTGS------DTMFVAPVTIGD 434 Query: 169 NNLIMGSCHIAHDCKIGDRNIFAN 192 + D G + A Sbjct: 435 GAYTGAGTVVREDVPPGALAVSAG 458 Score = 35.6 bits (80), Expect = 0.029, Method: Composition-based stats. Identities = 18/100 (18%), Positives = 33/100 (33%), Gaps = 15/100 (15%) Query: 136 DECFLCIGNNNEIREFCSIHRSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTL 195 D I + I IH ++ +T IG C +G + + Sbjct: 274 DPATTWIDVDVTIGRDTVIHPGTQLLGRTQIG------------GRCVVGPDTTLTDVAV 321 Query: 196 LAGHVVVEDNTHTAGASVVHQFCHIGSFAFIGGGSVVSQD 235 G VV + +S + +G F ++ G+ + D Sbjct: 322 GDGASVVRTH---GSSSSIGDGAAVGPFTYLRPGTALGAD 358 Score = 27.6 bits (59), Expect = 9.0, Method: Composition-based stats. Identities = 16/102 (15%), Positives = 33/102 (32%), Gaps = 2/102 (1%) Query: 150 EFCSIHRSSKPSDKTVIGDNN--LIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTH 207 + ++H S V G NN + + + + + ++ + Sbjct: 226 DGQTVHASHVDDSALVAGVNNRVQLAELASELNRRVVAAHQLAGVTVVDPATTWIDVDVT 285 Query: 208 TAGASVVHQFCHIGSFAFIGGGSVVSQDVPKYMMVAGERAEL 249 +V+H + IGG VV D + G+ A + Sbjct: 286 IGRDTVIHPGTQLLGRTQIGGRCVVGPDTTLTDVAVGDGASV 327 >4HUR-A nrPDB Length = 220 Score = 64.9 bits (156), Expect = 4e-11, Method: Composition-based stats. Identities = 29/134 (21%), Positives = 51/134 (38%), Gaps = 17/134 (12%) Query: 141 CIGNNNEIREFCSIHRSSKPSDKTVI--GDNNLIMGSCHIAHDCKIG--DRNIFANNTLL 196 IG+ I FCSI + T I G N+ + GS + H ++G + L Sbjct: 62 VIGDKLIIGRFCSIGPGT-----TFIMNGANHRMDGSTYPFHLFRMGWEKYMPSLKDLPL 116 Query: 197 AGHVVVEDNTHTAGASVVHQFCHIGSFAFIGGGSVVSQDVPKYMMVAGERAELRGLNLEG 256 G + + ++ + IG A I +VV+++V Y +V G + Sbjct: 117 KGDIEIGNDVWIGRDVTIMPGVKIGDGAIIAAEAVVTKNVAPYSIVGGNPLKFI------ 170 Query: 257 LRRNGFTMSEMKSL 270 R F+ ++ Sbjct: 171 --RKRFSDGVIEEW 182 Score = 40.7 bits (93), Expect = 9e-04, Method: Composition-based stats. Identities = 19/131 (14%), Positives = 37/131 (28%), Gaps = 2/131 (1%) Query: 47 VHPNAVIGKGVSVGPYCTIG-SSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVVGDEL 105 + P + + + VG Y + LY + +G C + G Sbjct: 27 IKPT-ITNENILVGEYSYYDSKRGESFEDQVLYHYEVIGDKLIIGRFCSIGPGTTFIMNG 85 Query: 106 PGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSSKPSDKTV 165 + G + K + + IGN+ I +I K D + Sbjct: 86 ANHRMDGSTYPFHLFRMGWEKYMPSLKDLPLKGDIEIGNDVWIGRDVTIMPGVKIGDGAI 145 Query: 166 IGDNNLIMGSC 176 I ++ + Sbjct: 146 IAAEAVVTKNV 156 Score = 33.0 bits (73), Expect = 0.21, Method: Composition-based stats. Identities = 19/94 (20%), Positives = 36/94 (38%), Gaps = 9/94 (9%) Query: 52 VIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVVGDELPGYTFI 111 IG V +G TI VK+G+G + + V N + ++VG + Sbjct: 121 EIGNDVWIGRDVTIMPGVKIGDGAIIAAEAVVTKN--------VAPYSIVGGNPLKFIRK 172 Query: 112 G-CNNIIGHHAVVGVKCQDLKYKHGDECFLCIGN 144 + +I + D+K + + F+ G+ Sbjct: 173 RFSDGVIEEWLALQWWNLDMKIINENLPFIINGD 206 Score = 29.5 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 7/33 (21%), Positives = 13/33 (39%) Query: 37 SEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSV 69 ++V I + P IG G + + +V Sbjct: 124 NDVWIGRDVTIMPGVKIGDGAIIAAEAVVTKNV 156 >4ISX-A nrPDB Length = 188 Score = 64.9 bits (156), Expect = 5e-11, Method: Composition-based stats. Identities = 22/87 (25%), Positives = 35/87 (40%) Query: 163 KTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFCHIGS 222 K IGDN ++ + I D + + V + DN G ++ IG Sbjct: 96 KIEIGDNVMLAPNVQIYTAYHPIDAQLRNSGIEYGSPVKIGDNVWIGGGVIITPGITIGD 155 Query: 223 FAFIGGGSVVSQDVPKYMMVAGERAEL 249 IG GSVV++D+P + G + Sbjct: 156 NVVIGAGSVVTKDIPPNTVAVGNPCRV 182 Score = 38.7 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 17/76 (22%), Positives = 29/76 (38%), Gaps = 18/76 (23%) Query: 52 VIGKGVSVGPYCTI------------------GSSVKLGNGCKLYPSSHVFGNTELGESC 93 IG V + P I GS VK+G+ + + +G++ Sbjct: 98 EIGDNVMLAPNVQIYTAYHPIDAQLRNSGIEYGSPVKIGDNVWIGGGVIITPGITIGDNV 157 Query: 94 VLMTGAVVGDELPGYT 109 V+ G+VV ++P T Sbjct: 158 VIGAGSVVTKDIPPNT 173 Score = 33.7 bits (75), Expect = 0.13, Method: Composition-based stats. Identities = 10/51 (19%), Positives = 19/51 (37%), Gaps = 5/51 (9%) Query: 51 AVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGN-----TELGESCVLM 96 IG V +G I + +G+ + S V + +G C ++ Sbjct: 133 VKIGDNVWIGGGVIITPGITIGDNVVIGAGSVVTKDIPPNTVAVGNPCRVI 183 Score = 33.3 bits (74), Expect = 0.13, Method: Composition-based stats. Identities = 13/59 (22%), Positives = 22/59 (37%), Gaps = 5/59 (8%) Query: 24 SSSLSYSREDSRDSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSS-----VKLGNGCKL 77 +S + Y V I ++ P IG V +G + V +GN C++ Sbjct: 124 NSGIEYGSPVKIGDNVWIGGGVIITPGITIGDNVVIGAGSVVTKDIPPNTVAVGNPCRV 182 >3R8Y-A nrPDB Length = 240 Score = 63.4 bits (152), Expect = 1e-10, Method: Composition-based stats. Identities = 34/133 (25%), Positives = 61/133 (45%), Gaps = 2/133 (1%) Query: 140 LCIGNNNEIREFCSIHRSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTL--LA 197 + IG+N I +I+ + + ++I N ++ G + +C +G + A A Sbjct: 104 VEIGDNAVIMMNATINIGAVIGEGSMIDMNAVLGGRATVGKNCHVGAGAVLAGVIEPPSA 163 Query: 198 GHVVVEDNTHTAGASVVHQFCHIGSFAFIGGGSVVSQDVPKYMMVAGERAELRGLNLEGL 257 V+VED+ VV + +G A + G+VV++DVP Y +VAG A + E Sbjct: 164 KPVIVEDDVVIGANVVVLEGVTVGKGAVVAAGAVVTEDVPPYTVVAGTPARVIKEIDEKT 223 Query: 258 RRNGFTMSEMKSL 270 + E++ L Sbjct: 224 KAKTEIKQELRQL 236 Score = 46.0 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 16/74 (21%), Positives = 33/74 (44%) Query: 33 DSRDSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGES 92 D + + I P A++ + IG + TI +G G + ++ + G +G++ Sbjct: 86 DLKGIKARIEPGAIIRDHVEIGDNAVIMMNATINIGAVIGEGSMIDMNAVLGGRATVGKN 145 Query: 93 CVLMTGAVVGDELP 106 C + GAV+ + Sbjct: 146 CHVGAGAVLAGVIE 159 Score = 39.1 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 18/110 (16%), Positives = 37/110 (33%), Gaps = 8/110 (7%) Query: 38 EVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYP--------SSHVFGNTEL 89 I+ AV+ ++I +G T+G + +G G L V + + Sbjct: 115 NATINIGAVIGEGSMIDMNAVLGGRATVGKNCHVGAGAVLAGVIEPPSAKPVIVEDDVVI 174 Query: 90 GESCVLMTGAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECF 139 G + V++ G VG + + VV + + ++ Sbjct: 175 GANVVVLEGVTVGKGAVVAAGAVVTEDVPPYTVVAGTPARVIKEIDEKTK 224 >2V0L-A nrPDB Length = 456 Score = 63.0 bits (151), Expect = 2e-10, Method: Composition-based stats. Identities = 36/186 (19%), Positives = 73/186 (39%), Gaps = 10/186 (5%) Query: 66 GSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVVGDELPGYTFIGCNNIIGHHAVVGV 125 G V++ + + + ++G CVL + D + ++I+G A +G Sbjct: 269 GKDVEIDVNVIIEGNVKLGDRVKIGTGCVLKNVVIGNDVEIKPYSVLEDSIVGEKAAIG- 327 Query: 126 KCQDLKYKHGDECFLCIGNNNEIREFCSIHRSSKPSDKTVIGDNNLIMGSCHIAHDCKIG 185 L+ +GN EI++ ++ + SK + T +GD I +C IG Sbjct: 328 PFSRLRPGAELAAETHVGNFVEIKK-STVGKGSKVNHLTYVGD-------SEIGSNCNIG 379 Query: 186 DRNIFANNTLLAG-HVVVEDNTHTAGASVVHQFCHIGSFAFIGGGSVVSQDVPKYMMVAG 244 I N ++ D+ + + + + A IG G+ +++DV + +V Sbjct: 380 AGVITCNYDGANKFKTIIGDDVFVGSDTQLVAPVKVANGATIGAGTTITRDVGENELVIT 439 Query: 245 ERAELR 250 A+ Sbjct: 440 RVAQRH 445 Score = 55.3 bits (131), Expect = 3e-08, Method: Composition-based stats. Identities = 25/134 (18%), Positives = 47/134 (35%), Gaps = 5/134 (3%) Query: 44 SAVVHPNAVIGKGVSVGPYC-----TIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTG 98 + V N VIG V + PY +G +G +L P + + T +G + Sbjct: 294 TGCVLKNVVIGNDVEIKPYSVLEDSIVGEKAAIGPFSRLRPGAELAAETHVGNFVEIKKS 353 Query: 99 AVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSS 158 V + ++ IG + +G Y ++ IG++ + + Sbjct: 354 TVGKGSKVNHLTYVGDSEIGSNCNIGAGVITCNYDGANKFKTIIGDDVFVGSDTQLVAPV 413 Query: 159 KPSDKTVIGDNNLI 172 K ++ IG I Sbjct: 414 KVANGATIGAGTTI 427 >2P2O-A nrPDB Length = 185 Score = 63.0 bits (151), Expect = 2e-10, Method: Composition-based stats. Identities = 29/109 (26%), Positives = 45/109 (41%), Gaps = 2/109 (1%) Query: 143 GNNNEIRE--FCSIHRSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHV 200 G N + E F + + IGD+ I HI D + + V Sbjct: 72 GYNIHVGENFFMNFDGVILDVCEVRIGDHCFIGPGVHIYTATHPLDPHERNSGLEYGKPV 131 Query: 201 VVEDNTHTAGASVVHQFCHIGSFAFIGGGSVVSQDVPKYMMVAGERAEL 249 V+ N G +V++ IG A I G+VV++DVP +V G A++ Sbjct: 132 VIGHNVWIGGRAVINPGVTIGDNAVIASGAVVTKDVPANAVVGGNPAKV 180 Score = 44.1 bits (102), Expect = 9e-05, Method: Composition-based stats. Identities = 17/83 (20%), Positives = 31/83 (37%), Gaps = 18/83 (21%) Query: 50 NAVIGKGVSVGPYCTI------------------GSSVKLGNGCKLYPSSHVFGNTELGE 91 IG +GP I G V +G+ + + + +G+ Sbjct: 94 EVRIGDHCFIGPGVHIYTATHPLDPHERNSGLEYGKPVVIGHNVWIGGRAVINPGVTIGD 153 Query: 92 SCVLMTGAVVGDELPGYTFIGCN 114 + V+ +GAVV ++P +G N Sbjct: 154 NAVIASGAVVTKDVPANAVVGGN 176 Score = 37.2 bits (84), Expect = 0.011, Method: Composition-based stats. Identities = 20/133 (15%), Positives = 40/133 (30%), Gaps = 27/133 (20%) Query: 54 GKGVSVGPY--CTIGSSVKLGNGCKLYPSSHVFG--NTELGESCVLMTGAVVGDELPGYT 109 G+ + + P C G ++ +G + + +G+ C + G + Sbjct: 58 GERLFIEPNFRCDYGYNIHVGENFFMNFDGVILDVCEVRIGDHCFIGPGVHI-------- 109 Query: 110 FIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSSKPSDKTVIGDN 169 + A + + + IG+N I I+ IGDN Sbjct: 110 ---------YTATHPLDPHERNSGLEYGKPVVIGHNVWIGGRAVINPG------VTIGDN 154 Query: 170 NLIMGSCHIAHDC 182 +I + D Sbjct: 155 AVIASGAVVTKDV 167 Score = 34.9 bits (78), Expect = 0.050, Method: Composition-based stats. Identities = 11/46 (23%), Positives = 17/46 (36%) Query: 24 SSSLSYSREDSRDSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSV 69 +S L Y + V I AV++P IG + + V Sbjct: 122 NSGLEYGKPVVIGHNVWIGGRAVINPGVTIGDNAVIASGAVVTKDV 167 >3IGJ-A nrPDB Length = 190 Score = 61.8 bits (148), Expect = 4e-10, Method: Composition-based stats. Identities = 21/87 (24%), Positives = 38/87 (43%) Query: 163 KTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFCHIGS 222 + IGD+ + HI + V + +N G ++++ IG Sbjct: 98 EVRIGDHCMFAPGVHIYTATHPLHPVERNSGKEYGKPVKIGNNVWVGGGAIINPGVSIGD 157 Query: 223 FAFIGGGSVVSQDVPKYMMVAGERAEL 249 A I G+VV++DVP ++V G A++ Sbjct: 158 NAVIASGAVVTKDVPNNVVVGGNPAKV 184 Score = 39.5 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 14/49 (28%), Positives = 26/49 (53%) Query: 66 GSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVVGDELPGYTFIGCN 114 G VK+GN + + + +G++ V+ +GAVV ++P +G N Sbjct: 132 GKPVKIGNNVWVGGGAIINPGVSIGDNAVIASGAVVTKDVPNNVVVGGN 180 Score = 33.7 bits (75), Expect = 0.12, Method: Composition-based stats. Identities = 9/55 (16%), Positives = 20/55 (36%), Gaps = 4/55 (7%) Query: 24 SSSLSYSREDSRDSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGS----SVKLGNG 74 +S Y + + V + A+++P IG + + +V +G Sbjct: 126 NSGKEYGKPVKIGNNVWVGGGAIINPGVSIGDNAVIASGAVVTKDVPNNVVVGGN 180 >1KK6-A nrPDB Length = 209 Score = 59.9 bits (143), Expect = 1e-09, Method: Composition-based stats. Identities = 29/141 (20%), Positives = 55/141 (39%), Gaps = 13/141 (9%) Query: 113 CNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSSKPSDKTVI--GDNN 170 N +G ++ K + K + + + +I +FCSI T+I G N+ Sbjct: 28 ENVEVGEYSYYDSKNGETFDKQILYHYPILNDKLKIGKFCSIGPGV-----TIIMNGANH 82 Query: 171 LIMGSCHIAHDCKIGD----RNIFANNTLLAGHVVVEDNTHTAGASVVHQFCHIGSFAFI 226 + GS + + G+ + + G ++ ++ V+ IG A + Sbjct: 83 RMDGSTYPFN--LFGNGWEKHMPKLDQLPIKGDTIIGNDVWIGKDVVIMPGVKIGDGAIV 140 Query: 227 GGGSVVSQDVPKYMMVAGERA 247 SVV +D+ YM+ G A Sbjct: 141 AANSVVVKDIAPYMLAGGNPA 161 Score = 32.2 bits (71), Expect = 0.36, Method: Composition-based stats. Identities = 25/145 (17%), Positives = 49/145 (33%), Gaps = 32/145 (22%) Query: 29 YSREDSRDSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTE 88 YS DS++ E +++ ++ + +G +C+IG V + Sbjct: 35 YSYYDSKNGETF--DKQILYHYPILNDKLKIGKFCSIGPGVTI----------------- 75 Query: 89 LGESCVLMTGAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEI 148 +M GA + Y F N H + + IGN+ I Sbjct: 76 ------IMNGANHRMDGSTYPFNLFGNGWEKHMPKLDQLP-------IKGDTIIGNDVWI 122 Query: 149 REFCSIHRSSKPSDKTVIGDNNLIM 173 + I K D ++ N++++ Sbjct: 123 GKDVVIMPGVKIGDGAIVAANSVVV 147 Score = 31.4 bits (69), Expect = 0.64, Method: Composition-based stats. Identities = 18/93 (19%), Positives = 32/93 (34%), Gaps = 3/93 (3%) Query: 65 IGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVVGDELPGYTFIGCN--NIIGHHAV 122 I +GN + + ++G+ ++ +VV ++ Y G N N I Sbjct: 110 IKGDTIIGNDVWIGKDVVIMPGVKIGDGAIVAANSVVVKDIAPYMLAGGNPANEIKQRFD 169 Query: 123 VGVKCQDLKYKHGDECFLCIGNNN-EIREFCSI 154 Q L K + I N +I + I Sbjct: 170 QDTINQLLDIKWWNWPIDIINENIDKILDNSII 202 >2OI7-A nrPDB Length = 456 Score = 59.9 bits (143), Expect = 2e-09, Method: Composition-based stats. Identities = 36/182 (19%), Positives = 68/182 (37%), Gaps = 16/182 (8%) Query: 23 LSSSLSYSREDSRDSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSH 82 L +L++ R+ V I + ++ N +G V +G C I + +G+ C++ P Sbjct: 262 LRGTLTHGRD------VEIDTNVIIEGNVTLGHRVKIGTGCVI-KNSVIGDDCEISPY-T 313 Query: 83 VFGNTELGESCVLMTGAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFL-- 140 V + L +C + A L + +G+ + K G +L Sbjct: 314 VVEDANLAAACTIGPFA----RLRPGAELLEGAHVGNFVEMKKARLGKGSKAGHLTYLGD 369 Query: 141 -CIGNNNEIREFC-SIHRSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAG 198 IG+N I + + KT+IGD+ + + +G A T + Sbjct: 370 AEIGDNVNIGAGTITCNYDGANKFKTIIGDDVFVGSDTQLVAPVTVGKGATIAAGTTVTR 429 Query: 199 HV 200 +V Sbjct: 430 NV 431 Score = 54.5 bits (129), Expect = 6e-08, Method: Composition-based stats. Identities = 44/211 (20%), Positives = 78/211 (36%), Gaps = 31/211 (14%) Query: 51 AVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVVGDELPGYTF 110 I V + T+G VK+G GC + N+ +G+ C + VV D Sbjct: 272 VEIDTNVIIEGNVTLGHRVKIGTGCVIK-------NSVIGDDCEISPYTVVED-----AN 319 Query: 111 IGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSSKPSDKTVIGDNN 170 + IG A + + L+ H +GN E+++ + + SK T +GD Sbjct: 320 LAAACTIGPFARLRPGAELLEGAH-------VGNFVEMKK-ARLGKGSKAGHLTYLGD-- 369 Query: 171 LIMGSCHIAHDCKIGDRNIFANNTLLAG-HVVVEDNTHTAGASVVHQFCHIGSFAFIGGG 229 I + IG I N ++ D+ + + +G A I G Sbjct: 370 -----AEIGDNVNIGAGTITCNYDGANKFKTIIGDDVFVGSDTQLVAPVTVGKGATIAAG 424 Query: 230 SVVSQDVPKYMMVAGERAELRGLNLEGLRRN 260 + V+++V + + + + EG RR Sbjct: 425 TTVTRNVGENALAI---SRVPQTQKEGWRRP 452 >3TWD-A nrPDB Length = 222 Score = 58.4 bits (139), Expect = 5e-09, Method: Composition-based stats. Identities = 36/182 (19%), Positives = 68/182 (37%), Gaps = 16/182 (8%) Query: 23 LSSSLSYSREDSRDSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSH 82 L +L++ R+ V I + ++ N +G V +G C I + +G+ C++ P Sbjct: 31 LRGTLTHGRD------VEIDTNVIIEGNVTLGHRVKIGTGCVI-KNSVIGDDCEISPY-T 82 Query: 83 VFGNTELGESCVLMTGAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFL-- 140 V + L +C + A L + +G+ + K G +L Sbjct: 83 VVEDANLAAACTIGPFA----RLRPGAELLEGAHVGNFVEMKKARLGKGSKAGHLTYLGD 138 Query: 141 -CIGNNNEIREFC-SIHRSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAG 198 IG+N I + + KT+IGD+ + + +G A T + Sbjct: 139 AEIGDNVNIGAGTITCNYDGANKFKTIIGDDVFVGSDTQLVAPVTVGKGATIAAGTTVTR 198 Query: 199 HV 200 +V Sbjct: 199 NV 200 Score = 53.4 bits (126), Expect = 1e-07, Method: Composition-based stats. Identities = 44/212 (20%), Positives = 78/212 (36%), Gaps = 31/212 (14%) Query: 51 AVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVVGDELPGYTF 110 I V + T+G VK+G GC + N+ +G+ C + VV D Sbjct: 41 VEIDTNVIIEGNVTLGHRVKIGTGCVIK-------NSVIGDDCEISPYTVVED-----AN 88 Query: 111 IGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSSKPSDKTVIGDNN 170 + IG A + + L+ H +GN E+++ + + SK T +GD Sbjct: 89 LAAACTIGPFARLRPGAELLEGAH-------VGNFVEMKK-ARLGKGSKAGHLTYLGD-- 138 Query: 171 LIMGSCHIAHDCKIGDRNIFANNTLLAG-HVVVEDNTHTAGASVVHQFCHIGSFAFIGGG 229 I + IG I N ++ D+ + + +G A I G Sbjct: 139 -----AEIGDNVNIGAGTITCNYDGANKFKTIIGDDVFVGSDTQLVAPVTVGKGATIAAG 193 Query: 230 SVVSQDVPKYMMVAGERAELRGLNLEGLRRNG 261 + V+++V + + + + EG RR Sbjct: 194 TTVTRNVGENALAI---SRVPQTQKEGWRRPA 222 >6MFK-A nrPDB Length = 216 Score = 57.6 bits (137), Expect = 8e-09, Method: Composition-based stats. Identities = 16/53 (30%), Positives = 29/53 (54%) Query: 197 AGHVVVEDNTHTAGASVVHQFCHIGSFAFIGGGSVVSQDVPKYMMVAGERAEL 249 AG ++ ++ G +++ IG A IG ++V++DV Y +V G A+L Sbjct: 116 AGDTIIGNDVWIGGEAMIMPGIKIGDGAVIGSRALVTKDVEPYAIVGGNPAKL 168 Score = 31.8 bits (70), Expect = 0.44, Method: Composition-based stats. Identities = 11/42 (26%), Positives = 18/42 (42%), Gaps = 10/42 (23%) Query: 37 SEVLIHPSAVVHPNAVIGKGVSVG----------PYCTIGSS 68 ++V I A++ P IG G +G PY +G + Sbjct: 123 NDVWIGGEAMIMPGIKIGDGAVIGSRALVTKDVEPYAIVGGN 164 Score = 31.4 bits (69), Expect = 0.53, Method: Composition-based stats. Identities = 9/48 (18%), Positives = 22/48 (45%) Query: 67 SSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVVGDELPGYTFIGCN 114 +GN + + + ++G+ V+ + A+V ++ Y +G N Sbjct: 117 GDTIIGNDVWIGGEAMIMPGIKIGDGAVIGSRALVTKDVEPYAIVGGN 164 Score = 30.3 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 19/97 (19%), Positives = 33/97 (34%), Gaps = 1/97 (1%) Query: 77 LYPSSHVFGNTELGESCVLMTGA-VVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHG 135 L P + +G C + TGA + G+ + ++ + ++ Sbjct: 55 LLPDRNDVDKLIIGSYCSVGTGASFIMAGNQGHRYDWISSFPFFYMNEVEAFENSIDAFK 114 Query: 136 DECFLCIGNNNEIREFCSIHRSSKPSDKTVIGDNNLI 172 + IGN+ I I K D VIG L+ Sbjct: 115 NAGDTIIGNDVWIGGEAMIMPGIKIGDGAVIGSRALV 151 >1T3D-A nrPDB Length = 289 Score = 56.4 bits (134), Expect = 2e-08, Method: Composition-based stats. Identities = 25/108 (23%), Positives = 38/108 (35%), Gaps = 6/108 (5%) Query: 146 NEIREFCSIHRSSKPSDKT--VIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVE 203 +I I R T V+G+ +I I +G + H + Sbjct: 158 VDIHPAAKIGRGIMLDHATGIVVGETAVIENDVSILQSVTLGG----TGKSGGDRHPKIR 213 Query: 204 DNTHTAGASVVHQFCHIGSFAFIGGGSVVSQDVPKYMMVAGERAELRG 251 + + + +G A IG GSVV Q VP + AG A + G Sbjct: 214 EGVMIGAGAKILGNIEVGRGAKIGAGSVVLQPVPPHTTAAGVPARIVG 261 Score = 29.9 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 36/81 (44%), Gaps = 14/81 (17%) Query: 39 VLIHPSAVVHPNAVIGKGVSVGP--------YCTIGSSVKLGNGCKLYPSSHVFGNTELG 90 +++ +AV+ + I + V++G + I V +G G + + GN E+G Sbjct: 178 IVVGETAVIENDVSILQSVTLGGTGKSGGDRHPKIREGVMIGAG------AKILGNIEVG 231 Query: 91 ESCVLMTGAVVGDELPGYTFI 111 + G+VV +P +T Sbjct: 232 RGAKIGAGSVVLQPVPPHTTA 252 >3TIO-A nrPDB Length = 183 Score = 54.9 bits (130), Expect = 5e-08, Method: Composition-based stats. Identities = 28/141 (19%), Positives = 56/141 (39%), Gaps = 20/141 (14%) Query: 88 ELGESCVLMTGAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNE 147 ++G+ ++ +VV G + + I V+ GD ++ IG Sbjct: 13 QIGQRVMIDDSSVV----IGDVRLADDVGIWPLVVI----------RGDVHYVQIGARTN 58 Query: 148 IREFCSIHRSSK-----PSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVV 202 I++ +H + K + IG++ + + H C IG+R + ++L +V Sbjct: 59 IQDGSMLHVTHKSSYNPDGNPLTIGEDVTVGHKVML-HGCTIGNRVLVGMGSILLDGAIV 117 Query: 203 EDNTHTAGASVVHQFCHIGSF 223 ED+ S+V Q + S Sbjct: 118 EDDVMIGAGSLVPQNKRLESG 138 Score = 40.3 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 22/162 (13%), Positives = 55/162 (33%), Gaps = 30/162 (18%) Query: 38 EVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHV---FGNTELGESCV 94 ++HP + P IG+ V + + V+L + ++P + ++G Sbjct: 1 SDVLHPYRDLFP--QIGQRVMIDDSSVVIGDVRLADDVGIWPLVVIRGDVHYVQIGARTN 58 Query: 95 LMTGAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSI 154 + G+++ + D L IG + + + Sbjct: 59 IQDGSMLHVT------------------------HKSSYNPDGNPLTIGEDVTVGHKVML 94 Query: 155 HRSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLL 196 H + ++ ++G ++++ + D IG ++ N L Sbjct: 95 HGCT-IGNRVLVGMGSILLDGAIVEDDVMIGAGSLVPQNKRL 135 >6F3A-U nrPDB Length = 190 Score = 54.9 bits (130), Expect = 5e-08, Method: Composition-based stats. Identities = 34/147 (23%), Positives = 55/147 (37%), Gaps = 11/147 (7%) Query: 67 SSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVVGDELPGYTFIGCNNIIGHHAVVGVK 126 SVK+ G + S + G+ +G V+ A + E G IG N+I A++ Sbjct: 7 KSVKIAPGAVVCVESEIRGDVTIGPRTVIHPKARIIAEA-GPIVIGEGNLIEEQALIINA 65 Query: 127 CQD---LKYKHGDECFLCIGNNNEIREFCSIHRSSKPSDKTVIGDNNLIMGSCHIAHDCK 183 D + + + IG NN C S +GDNN+I ++ + Sbjct: 66 HPDNITPDAEDSEPKPMIIGTNNVFEVGC-------YSQAMKMGDNNVIESKAYVGRNVI 118 Query: 184 IGDRNIFANNTLLAGHVVVEDNTHTAG 210 + I L V+ +NT G Sbjct: 119 LTSGCIIGACCNLNTFEVIPENTVIYG 145 Score = 39.5 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 32/168 (19%), Positives = 57/168 (33%), Gaps = 43/168 (25%) Query: 91 ESCVLMTGAVV--GDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEI 148 +S + GAVV E+ G IG +I A + + + IG N I Sbjct: 7 KSVKIAPGAVVCVESEIRGDVTIGPRTVIHPKARI----------IAEAGPIVIGEGNLI 56 Query: 149 REFCSI----------HRSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAG 198 E I +IG NN+ C+ + K+GD N+ + + Sbjct: 57 EEQALIINAHPDNITPDAEDSEPKPMIIGTNNVFEVGCY-SQAMKMGDNNVIESKAYVGR 115 Query: 199 HVVVEDNTHTAGASVVHQFCHIGSFAFIGGGSVVS--QDVPKYMMVAG 244 +V++ S IG ++ + +P+ ++ G Sbjct: 116 NVILT------------------SGCIIGACCNLNTFEVIPENTVIYG 145 Score = 28.7 bits (62), Expect = 3.4, Method: Composition-based stats. Identities = 9/40 (22%), Positives = 19/40 (47%) Query: 46 VVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFG 85 V+ A +G+ V + C IG+ L + ++ ++G Sbjct: 106 VIESKAYVGRNVILTSGCIIGACCNLNTFEVIPENTVIYG 145 >4H7O-A nrPDB Length = 281 Score = 54.1 bits (128), Expect = 9e-08, Method: Composition-based stats. Identities = 27/108 (25%), Positives = 40/108 (37%), Gaps = 6/108 (5%) Query: 146 NEIREFCSIHRSSKPSDKT--VIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVE 203 +I I R T VIG+ ++ I D +G + H + Sbjct: 142 VDIHPAARIGRGIMLDHATGIVIGETAVVEDDVSILQDVTLGGTGKECGDR----HPKIR 197 Query: 204 DNTHTAGASVVHQFCHIGSFAFIGGGSVVSQDVPKYMMVAGERAELRG 251 + + + +G A IG GSVV Q VP + VAG A + G Sbjct: 198 EGVMIGAGAKILGNIEVGEGAKIGSGSVVLQAVPPHTTVAGVPARIVG 245 Score = 36.8 bits (83), Expect = 0.014, Method: Composition-based stats. Identities = 26/116 (22%), Positives = 47/116 (40%), Gaps = 15/116 (12%) Query: 39 VLIHPSAVVHPNAVIGKGVSVGP--------YCTIGSSVKLGNGCKLYPSSHVFGNTELG 90 ++I +AVV + I + V++G + I V +G G + + GN E+G Sbjct: 162 IVIGETAVVEDDVSILQDVTLGGTGKECGDRHPKIREGVMIGAG------AKILGNIEVG 215 Query: 91 ESCVLMTGAVVGDELPGYTFI-GCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNN 145 E + +G+VV +P +T + G I D+ + IG + Sbjct: 216 EGAKIGSGSVVLQAVPPHTTVAGVPARIVGRPQSDKPSLDMDQQFNGRSQTFIGGD 271 >3CJ8-A nrPDB Length = 236 Score = 53.8 bits (127), Expect = 9e-08, Method: Composition-based stats. Identities = 30/134 (22%), Positives = 57/134 (42%), Gaps = 2/134 (1%) Query: 139 FLCIGNNNEIREFCSIHRSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTL--L 196 + IG+ I ++ + T+I ++ G + C IG + A Sbjct: 103 KVEIGDQAVIMMGAILNIGAVVGAGTMIDMGAVLGGRATVGKHCHIGAGTVLAGVIEPPS 162 Query: 197 AGHVVVEDNTHTAGASVVHQFCHIGSFAFIGGGSVVSQDVPKYMMVAGERAELRGLNLEG 256 A VV+E+ +VV + +G A + G+VV +DVP + +VAG A++ + Sbjct: 163 AAPVVIENEVVIGANAVVLEGVRVGEGAVVAAGAVVVEDVPAHTVVAGVPAKVIKQIDDK 222 Query: 257 LRRNGFTMSEMKSL 270 + + E++ L Sbjct: 223 TKSKTEILEELRKL 236 Score = 52.6 bits (124), Expect = 2e-07, Method: Composition-based stats. Identities = 20/97 (20%), Positives = 36/97 (37%), Gaps = 4/97 (4%) Query: 33 DSRDSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGES 92 D +D I P A++ IG + + +G G + + + G +G+ Sbjct: 86 DLKDINARIEPGALIREKVEIGDQAVIMMGAILNIGAVVGAGTMIDMGAVLGGRATVGKH 145 Query: 93 CVLMTGAVVGDELP----GYTFIGCNNIIGHHAVVGV 125 C + G V+ + I +IG +AVV Sbjct: 146 CHIGAGTVLAGVIEPPSAAPVVIENEVVIGANAVVLE 182 >3FWW-A nrPDB Length = 456 Score = 53.0 bits (125), Expect = 2e-07, Method: Composition-based stats. Identities = 39/210 (18%), Positives = 78/210 (37%), Gaps = 33/210 (15%) Query: 53 IGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVVGD-ELPGYTFI 111 I V + + +G V++G GC L N +G+ + V+ D L + Sbjct: 274 IDTNVIIEGHVILGDRVRIGTGCVLK-------NCVIGDDSEISPYTVLEDARLDANCTV 326 Query: 112 GCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSSKPSDKTVIGDNNL 171 G + A + +GN EI++ + + SK + +GD Sbjct: 327 GPFARLRPGAELAE-------------GAHVGNFVEIKK-ARLGKGSKAGHLSYLGD--- 369 Query: 172 IMGSCHIAHDCKIGDRNIFANNTLLAG-HVVVEDNTHTAGASVVHQFCHIGSFAFIGGGS 230 I IG I N ++ D+ + + + + A IG G+ Sbjct: 370 ----AEIGAGVNIGAGTITCNYDGANKFKTIIGDDVFVGSDTQLVAPVTVANGATIGAGT 425 Query: 231 VVSQDVPKYMMVAGERAELRGLNLEGLRRN 260 V++DV + +V + ++ ++++G +R Sbjct: 426 TVTRDVAENELVI---SRVKQVHIQGWKRP 452 Score = 50.7 bits (119), Expect = 8e-07, Method: Composition-based stats. Identities = 30/135 (22%), Positives = 50/135 (37%), Gaps = 13/135 (9%) Query: 32 EDSR-DSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELG 90 ED+R D+ + P A + P A + +G VG + I +LG G K G+ E+G Sbjct: 316 EDARLDANCTVGPFARLRPGAELAEGAHVGNFVEI-KKARLGKGSK-AGHLSYLGDAEIG 373 Query: 91 ESCVLMTGAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIRE 150 + G + + F IIG VG Q + + N I Sbjct: 374 AGVNIGAGTITCNYDGANKF---KTIIGDDVFVGSDTQ-------LVAPVTVANGATIGA 423 Query: 151 FCSIHRSSKPSDKTV 165 ++ R ++ + Sbjct: 424 GTTVTRDVAENELVI 438 Score = 50.7 bits (119), Expect = 9e-07, Method: Composition-based stats. Identities = 26/176 (14%), Positives = 57/176 (32%), Gaps = 22/176 (12%) Query: 23 LSSSLSYSREDSRDSEVLIHP-----------SAVVHPNAVIGKGVSVGPYCTI-----G 66 L L++ R+ + D+ V+I + V N VIG + PY + Sbjct: 262 LRGELTHGRDITIDTNVIIEGHVILGDRVRIGTGCVLKNCVIGDDSEISPYTVLEDARLD 321 Query: 67 SSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVVGDELPGYTFIGCNNIIGHHAVVGVK 126 ++ +G +L P + + +G + + G+ + IG +G Sbjct: 322 ANCTVGPFARLRPGAELAEGAHVGNFVEIKKARLGKGSKAGHLSYLGDAEIGAGVNIGAG 381 Query: 127 CQDLKYKHGDECFLCIGNNNEIREFCSIHRSSKPSDKTVIGDNNLIMGSCHIAHDC 182 Y ++ IG++ + ++ + + I + D Sbjct: 382 TITCNYDGANKFKTIIGDDVFVGS------DTQLVAPVTVANGATIGAGTTVTRDV 431 >3GVD-A nrPDB Length = 276 Score = 52.2 bits (123), Expect = 3e-07, Method: Composition-based stats. Identities = 25/108 (23%), Positives = 38/108 (35%), Gaps = 6/108 (5%) Query: 146 NEIREFCSIHRSSKPSDKT--VIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVE 203 +I +I T VIG+ ++ I +G T H + Sbjct: 145 VDIHPAATIGCGIMLDHATGIVIGETAVVENDVSILQSVTLGG----TGKTSGDRHPKIR 200 Query: 204 DNTHTAGASVVHQFCHIGSFAFIGGGSVVSQDVPKYMMVAGERAELRG 251 + + + +G A IG GSVV Q VP + AG A + G Sbjct: 201 EGVMIGAGAKILGNIEVGRGAKIGAGSVVLQSVPAHTTAAGVPARIVG 248 Score = 30.3 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 20/81 (24%), Positives = 36/81 (44%), Gaps = 14/81 (17%) Query: 39 VLIHPSAVVHPNAVIGKGVSVGP--------YCTIGSSVKLGNGCKLYPSSHVFGNTELG 90 ++I +AVV + I + V++G + I V +G G + + GN E+G Sbjct: 165 IVIGETAVVENDVSILQSVTLGGTGKTSGDRHPKIREGVMIGAG------AKILGNIEVG 218 Query: 91 ESCVLMTGAVVGDELPGYTFI 111 + G+VV +P +T Sbjct: 219 RGAKIGAGSVVLQSVPAHTTA 239 >5Z09-A nrPDB Length = 409 Score = 51.4 bits (121), Expect = 5e-07, Method: Composition-based stats. Identities = 23/172 (13%), Positives = 51/172 (29%), Gaps = 9/172 (5%) Query: 53 IGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVVGDELPGYTFIG 112 + V + I ++ +G + ++ +E+G + L ++ ++ IG Sbjct: 235 VEDNVKIKGKVIIEEDAEIKSGTYIEGPVYIGKGSEIGPNSYLRPYTILVEK----NKIG 290 Query: 113 CNNIIGHHAVV-GVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSSKPSDKTVIGDNNL 171 + + ++ G K L Y I + I + + Sbjct: 291 ASVEVKESVIMEGSKIPHLSY----VGDSVIAEDVNFGAGTLIANLRFDEKEVKVNVKGK 346 Query: 172 IMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFCHIGSF 223 + S IG N + V + +VV++ G F Sbjct: 347 RISSGRRKLGAFIGGHVRTGINVTILPGVKIGAYARIYPGAVVNRDVGYGEF 398 >5AFU-U nrPDB Length = 168 Score = 51.1 bits (120), Expect = 8e-07, Method: Composition-based stats. Identities = 31/137 (22%), Positives = 51/137 (37%), Gaps = 9/137 (6%) Query: 74 GCKLYPSSHVFGNTELGESCVLMTGAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYK 133 G + S + G+ +G V+ A + E G IG N+I A++ D Sbjct: 2 GAVVCVESEIRGDVTIGPRTVIHPKARIIAEA-GPIVIGEGNLIEEQALIINAYPDNITP 60 Query: 134 HGDECFLCIGNNNEIREFCSIHRSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANN 193 ++ + IG NN C S +GDNN+I ++ + + I Sbjct: 61 DTEK-PMIIGTNNVFEVGC-------YSQAMKMGDNNVIESKAYVGRNVILTSGCIIGAC 112 Query: 194 TLLAGHVVVEDNTHTAG 210 L V+ +NT G Sbjct: 113 CNLNTFEVIPENTVIYG 129 Score = 40.3 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 31/158 (19%), Positives = 56/158 (35%), Gaps = 39/158 (24%) Query: 97 TGAVV--GDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSI 154 GAVV E+ G IG +I A + + + IG N I E I Sbjct: 1 PGAVVCVESEIRGDVTIGPRTVIHPKARI----------IAEAGPIVIGEGNLIEEQALI 50 Query: 155 ------HRSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHT 208 + + +IG NN+ C+ + K+GD N+ + + +V++ Sbjct: 51 INAYPDNITPDTEKPMIIGTNNVFEVGCY-SQAMKMGDNNVIESKAYVGRNVILT----- 104 Query: 209 AGASVVHQFCHIGSFAFIGGGSVVS--QDVPKYMMVAG 244 S IG ++ + +P+ ++ G Sbjct: 105 -------------SGCIIGACCNLNTFEVIPENTVIYG 129 Score = 28.7 bits (62), Expect = 3.4, Method: Composition-based stats. Identities = 9/40 (22%), Positives = 19/40 (47%) Query: 46 VVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFG 85 V+ A +G+ V + C IG+ L + ++ ++G Sbjct: 90 VIESKAYVGRNVILTSGCIIGACCNLNTFEVIPENTVIYG 129 >1THJ-A nrPDB Length = 214 Score = 50.7 bits (119), Expect = 8e-07, Method: Composition-based stats. Identities = 35/180 (19%), Positives = 58/180 (32%), Gaps = 27/180 (15%) Query: 37 SEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLM 96 S +I P+A + P A + V++G + + S +G+ + Sbjct: 25 SAPVIDPTAYIDPEASVIGEVTIGANVMVSPMASI--------RSDEGMPIFVGDRSNVQ 76 Query: 97 TGAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHR 156 G V L I +V V G E + IGNN + +H Sbjct: 77 DGVV----LHALETINEEGEPIEDNIVEVD--------GKEYAVYIGNNVSLAHQSQVHG 124 Query: 157 SSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQ 216 + D T IG + S K+G+ + + G + + AG V Q Sbjct: 125 PAAVGDDTFIGMQAFVFKS-------KVGNNCVLEPRSAAIGVTIPDGRYIPAGMVVTSQ 177 Score = 34.9 bits (78), Expect = 0.052, Method: Composition-based stats. Identities = 25/156 (16%), Positives = 52/156 (33%), Gaps = 28/156 (17%) Query: 103 DELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSSKPSD 162 + G IG N ++ A + + + + +G+ + +++ +H ++ Sbjct: 39 ASVIGEVTIGANVMVSPMASI---------RSDEGMPIFVGDRSNVQDGVVLHALETINE 89 Query: 163 KTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFCHIGS 222 + I D + + A V + +N A S VH +G Sbjct: 90 E-----------------GEPIEDNIVEVDGKEYA--VYIGNNVSLAHQSQVHGPAAVGD 130 Query: 223 FAFIGGGSVVSQDVPKYMMVAGERAELRGLNLEGLR 258 FIG + V + V R+ G+ + R Sbjct: 131 DTFIGMQAFVFKSKVGNNCVLEPRSAAIGVTIPDGR 166 >3Q1X-A nrPDB Length = 313 Score = 50.7 bits (119), Expect = 9e-07, Method: Composition-based stats. Identities = 22/123 (17%), Positives = 39/123 (31%), Gaps = 17/123 (13%) Query: 47 VHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVVGDELP 106 +HP A I + G V +G + ++ + LG G V+ Sbjct: 166 IHPGASIKGHFFIDH----GVGVVIGETAIIGEWCRIYQSVTLGAMHFQEEGGVIKRGTK 221 Query: 107 GYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSSKPSDKTVI 166 + +G IG A V + +G++ I C I R + I Sbjct: 222 RHPTVGDYVTIGTGAKV-------------LGNIIVGSHVRIGANCWIDRDVDSNQTVYI 268 Query: 167 GDN 169 ++ Sbjct: 269 SEH 271 Score = 38.7 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 21/101 (20%), Positives = 30/101 (29%), Gaps = 12/101 (11%) Query: 154 IHRSSKPSD--------KTVIGDNNLIMGSCHIAHDCKIGD-RNIFANNTLLAG---HVV 201 IH + VIG+ +I C I +G + G H Sbjct: 166 IHPGASIKGHFFIDHGVGVVIGETAIIGEWCRIYQSVTLGAMHFQEEGGVIKRGTKRHPT 225 Query: 202 VEDNTHTAGASVVHQFCHIGSFAFIGGGSVVSQDVPKYMMV 242 V D + V +GS IG + +DV V Sbjct: 226 VGDYVTIGTGAKVLGNIIVGSHVRIGANCWIDRDVDSNQTV 266 Score = 28.3 bits (61), Expect = 4.5, Method: Composition-based stats. Identities = 13/70 (18%), Positives = 22/70 (31%), Gaps = 8/70 (11%) Query: 48 HPNAVIGKGVSVGPYC------TIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVV 101 HP +G V++G +GS V++G C + + E Sbjct: 223 HPT--VGDYVTIGTGAKVLGNIIVGSHVRIGANCWIDRDVDSNQTVYISEHPTHFVKPCT 280 Query: 102 GDELPGYTFI 111 + T I Sbjct: 281 TKGMKNDTEI 290 >2NPO-A nrPDB Length = 207 Score = 50.3 bits (118), Expect = 1e-06, Method: Composition-based stats. Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 6/86 (6%) Query: 40 LIHPSAVVHPNAVIGKGV--SVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMT 97 LIH SA++ P+A++ + + PY I + K+ G L SS + +GE + Sbjct: 80 LIHKSALISPSAIVEENAGILIMPYVVINAKAKIEKGVILNTSSVIEHECVIGE----FS 135 Query: 98 GAVVGDELPGYTFIGCNNIIGHHAVV 123 VG + G IG N +G ++ V Sbjct: 136 HVSVGAKCAGNVKIGKNCFLGINSCV 161 Score = 47.2 bits (110), Expect = 9e-06, Method: Composition-based stats. Identities = 26/139 (18%), Positives = 53/139 (38%), Gaps = 9/139 (6%) Query: 113 CNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNN---EIREFCSIHRSSKPSDKTVIGDN 169 I + G K +L +K I N I + I+ +K ++ + Sbjct: 63 RKKIYQKISENGFKIVNLIHKSALISPSAIVEENAGILIMPYVVINAKAKIEKGVILNTS 122 Query: 170 NLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFCHIGSFAFIGGG 229 ++ I H+C IG+ + + AG+V + N S V + + +GGG Sbjct: 123 SV------IEHECVIGEFSHVSVGAKCAGNVKIGKNCFLGINSCVLPNLSLADDSILGGG 176 Query: 230 SVVSQDVPKYMMVAGERAE 248 + + ++ + + G A+ Sbjct: 177 ATLVKNQDEKGVFVGVPAK 195 Score = 43.4 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 27/108 (25%), Positives = 45/108 (41%), Gaps = 5/108 (4%) Query: 24 SSSLSYSREDSRDSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHV 83 S+ +S S ++ +LI P V++ A I KGV + I +G + + Sbjct: 84 SALISPSAIVEENAGILIMPYVVINAKAKIEKGVILNTSSVIEHECVIGEFSHVSVGAKC 143 Query: 84 FGNTELGESCVLMTGAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLK 131 GN ++G++C L + V L ++ I VK QD K Sbjct: 144 AGNVKIGKNCFLGINSCVLPNLSL-----ADDSILGGGATLVKNQDEK 186 >6JLY-I nrPDB Length = 678 Score = 50.3 bits (118), Expect = 1e-06, Method: Composition-based stats. Identities = 25/69 (36%), Positives = 33/69 (47%), Gaps = 2/69 (2%) Query: 140 LCIGNNNEIREFCSIHRSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGH 199 IG N I CSI + D VIGDN I G +A+ KIG+ + ++A Sbjct: 348 TIIGRNCTIGSNCSIDSAFLWED-VVIGDNCRI-GKAILANSVKIGNNCSIEDGAIVAAG 405 Query: 200 VVVEDNTHT 208 VV+ DNT Sbjct: 406 VVIGDNTII 414 Score = 45.7 bits (106), Expect = 3e-05, Method: Composition-based stats. Identities = 24/116 (20%), Positives = 44/116 (37%), Gaps = 14/116 (12%) Query: 54 GKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVVGDELPGYTFIGC 113 + V + C I + +G K+ + V NT +G +C + + + F+ Sbjct: 316 EEDVVLARSCIIKARTLIGAYTKVG-DASVVANTIIGRNCTIGSNCSI-----DSAFLWE 369 Query: 114 NNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSSKPSDKTVIGDN 169 + +IG + +G K + IGNN I + + D T+I N Sbjct: 370 DVVIGDNCRIG--------KAILANSVKIGNNCSIEDGAIVAAGVVIGDNTIIEKN 417 Score = 43.0 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 30/146 (20%), Positives = 59/146 (40%), Gaps = 28/146 (19%) Query: 23 LSSSLSYSRED-SRDSEVLIHPSAVVHPNAVIGK-----------GVSVGPYCTIGSS-- 68 L+ + SY R ++ +V++ S ++ +IG +G CTIGS+ Sbjct: 302 LNQTFSYQRHQIYKEEDVVLARSCIIKARTLIGAYTKVGDASVVANTIIGRNCTIGSNCS 361 Query: 69 ---------VKLGNGCKLYPSSHVFGNTELGESCVLMTGAVVGDELPGYTFIGCNNIIGH 119 V +G+ C++ + + + ++G +C + GA+V + IG N II Sbjct: 362 IDSAFLWEDVVIGDNCRIG-KAILANSVKIGNNCSIEDGAIVAAGVV----IGDNTIIEK 416 Query: 120 HAVVGVKCQDLKYKHGDECFLCIGNN 145 + + + D + IG Sbjct: 417 NKRLTTFESHSQGTLNDPSLVGIGGR 442 >1XAT-A nrPDB Length = 212 Score = 49.9 bits (117), Expect = 2e-06, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 31/80 (38%), Gaps = 8/80 (10%) Query: 191 ANNTLLAGHVVVEDNTHTAGASVVHQFCHIGSFAFIGGGSVVSQDVPKYMMVAGERAELR 250 N AG ++ ++ +G A IG ++V+ DV Y +V G A Sbjct: 102 VNGYQPAGDTLIGHEVWIGTEAMFMPGVRVGHGAIIGSRALVTGDVEPYAIVGGNPARTI 161 Query: 251 GLNLEGLRRNGFTMSEMKSL 270 R F+ ++++L Sbjct: 162 --------RKRFSDGDIQNL 173 >6I7T-G nrPDB Length = 712 Score = 49.9 bits (117), Expect = 2e-06, Method: Composition-based stats. Identities = 27/114 (23%), Positives = 53/114 (46%), Gaps = 8/114 (7%) Query: 48 HPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVVGDELPG 107 + V+ + +G IGS K+G G K+ +S + N ++GE+ + + D + G Sbjct: 328 EKDVVLAQSCKIGKCTAIGSGTKIGEGTKIE-NSVIGRNCQIGENIRIKNSFIWDDCIIG 386 Query: 108 YTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSSKPS 161 I +++I +A +G ++ G IG N +I + + R++K S Sbjct: 387 NNSIIDHSLIASNATLGSN---VRLNDG----CIIGFNVKIDDNMDLDRNTKIS 433 Score = 46.8 bits (109), Expect = 1e-05, Method: Composition-based stats. Identities = 28/174 (16%), Positives = 62/174 (35%), Gaps = 12/174 (6%) Query: 89 LGESCV---LMTGAVVGDELPGYTFIGCN--NIIGHHAVVGVKCQDLKYKHGDECFLCIG 143 LG+ AV + Y I + + V+ QD + + + Sbjct: 269 LGKHIYAYLTDEYAVRVESWQTYDTISQDFLGRWCYPLVLDSNIQDDQTYSYESRHIYKE 328 Query: 144 NNNEIREFCSIHRSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTL----LAGH 199 + + + C I + + T IG+ I S I +C+IG+ N+ + + G+ Sbjct: 329 KDVVLAQSCKIGKCTAIGSGTKIGEGTKIENSV-IGRNCQIGENIRIKNSFIWDDCIIGN 387 Query: 200 VVVEDNTHTAGASVVHQFCHIGSFAFIGGGSVV--SQDVPKYMMVAGERAELRG 251 + D++ A + + + IG + + D+ + ++ + G Sbjct: 388 NSIIDHSLIASNATLGSNVRLNDGCIIGFNVKIDDNMDLDRNTKISASPLKNAG 441 Score = 34.9 bits (78), Expect = 0.058, Method: Composition-based stats. Identities = 14/64 (21%), Positives = 30/64 (46%), Gaps = 1/64 (1%) Query: 32 EDSRDSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGE 91 E+ R I ++ N++I + T+GS+V+L +GC + + + N +L Sbjct: 370 ENIRIKNSFIWDDCIIGNNSII-DHSLIASNATLGSNVRLNDGCIIGFNVKIDDNMDLDR 428 Query: 92 SCVL 95 + + Sbjct: 429 NTKI 432 >1SST-A nrPDB Length = 267 Score = 48.7 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 23/109 (21%), Positives = 39/109 (35%), Gaps = 6/109 (5%) Query: 145 NNEIREFCSIHRSSKPSDKT--VIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVV 202 + +I I T V+G+ ++I I +G + + H V Sbjct: 137 DVDIHPAAKIGHGIMFDHATGIVVGETSVIENDVSILQGVTLGGTGKESGDR----HPKV 192 Query: 203 EDNTHTAGASVVHQFCHIGSFAFIGGGSVVSQDVPKYMMVAGERAELRG 251 + + + +G +A IG SVV VP+Y AG A + Sbjct: 193 REGVMIGAGAKILGNIEVGKYAKIGANSVVLNPVPEYATAAGVPARIVS 241 Score = 28.3 bits (61), Expect = 4.7, Method: Composition-based stats. Identities = 12/65 (18%), Positives = 31/65 (47%), Gaps = 8/65 (12%) Query: 39 VLIHPSAVVHPNAVIGKGVSVGP--------YCTIGSSVKLGNGCKLYPSSHVFGNTELG 90 +++ ++V+ + I +GV++G + + V +G G K+ + V ++G Sbjct: 158 IVVGETSVIENDVSILQGVTLGGTGKESGDRHPKVREGVMIGAGAKILGNIEVGKYAKIG 217 Query: 91 ESCVL 95 + V+ Sbjct: 218 ANSVV 222 >4HZC-A nrPDB Length = 281 Score = 46.8 bits (109), Expect = 1e-05, Method: Composition-based stats. Identities = 19/87 (21%), Positives = 34/87 (39%), Gaps = 4/87 (4%) Query: 165 VIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFCHIGSFA 224 V+G+ ++ + I H +G + H + + + +G + Sbjct: 173 VVGETAVVEDNVSILHGVTLGG----TGKSSGDRHPKIRQGVLIGAGAKILGNIQVGQCS 228 Query: 225 FIGGGSVVSQDVPKYMMVAGERAELRG 251 I GSVV + VP + VAG A + G Sbjct: 229 KIAAGSVVLKSVPHNVTVAGVPARIIG 255 Score = 36.0 bits (81), Expect = 0.023, Method: Composition-based stats. Identities = 18/108 (16%), Positives = 37/108 (34%), Gaps = 15/108 (13%) Query: 47 VHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELG--------ESCVLMTG 98 +HP A +G G+ + + + +G + + + LG + G Sbjct: 154 IHPAARLGSGLFLDH----ATGLVVGETAVVEDNVSILHGVTLGGTGKSSGDRHPKIRQG 209 Query: 99 AVV--GDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGN 144 ++ G ++ G +G + I +VV G + IG Sbjct: 210 VLIGAGAKILGNIQVGQCSKIAAGSVVLKSVPHNVTVAGVPARI-IGE 256 >5UX9-A nrPDB Length = 221 Score = 44.5 bits (103), Expect = 6e-05, Method: Composition-based stats. Identities = 21/117 (17%), Positives = 42/117 (35%), Gaps = 6/117 (5%) Query: 123 VGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSSKPSDKTVIGDNNLIMGSCHIAHDC 182 +G ++ G + + I +FCSI + + G+ Sbjct: 51 LGDAPTQEVWESGQFGEV---DKLRIGKFCSIASGATF---MMAGNQGHRADWISTFPFS 104 Query: 183 KIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFCHIGSFAFIGGGSVVSQDVPKY 239 K + AG +V ++ +++ HIG A IG +V++++V Y Sbjct: 105 KKEFGEGVKDGFQRAGDTIVGNDVWIGSEAMIMPGVHIGDGAIIGARAVITKNVAPY 161 Score = 35.3 bits (79), Expect = 0.037, Method: Composition-based stats. Identities = 10/33 (30%), Positives = 16/33 (48%) Query: 37 SEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSV 69 ++V I A++ P IG G +G I +V Sbjct: 126 NDVWIGSEAMIMPGVHIGDGAIIGARAVITKNV 158 Score = 29.1 bits (63), Expect = 3.1, Method: Composition-based stats. Identities = 7/36 (19%), Positives = 15/36 (41%) Query: 64 TIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGA 99 +G+ V +G+ + P H+ +G V+ Sbjct: 123 IVGNDVWIGSEAMIMPGVHIGDGAIIGARAVITKNV 158 Score = 27.9 bits (60), Expect = 6.6, Method: Composition-based stats. Identities = 8/42 (19%), Positives = 16/42 (38%) Query: 34 SRDSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGC 75 R + ++ + A+I GV +G IG+ + Sbjct: 117 QRAGDTIVGNDVWIGSEAMIMPGVHIGDGAIIGARAVITKNV 158 >2QKX-A nrPDB Length = 391 Score = 44.1 bits (102), Expect = 9e-05, Method: Composition-based stats. Identities = 27/122 (22%), Positives = 41/122 (33%), Gaps = 16/122 (13%) Query: 36 DSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGS-----SVKLGNGCKL----YPSSHVFGN 86 D +V I V+HP + +G C +G V +G+G + SS + Sbjct: 277 DVDVTIGRDTVIHPGTQLLGRTQIGGRCVVGPDTTLTDVAVGDGASVVRTHGSSSSIGDG 336 Query: 87 TELGESCVLMTGAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNN 146 +G L G +G + F+ N G K L Y IG + Sbjct: 337 AAVGPFTYLRPGTALGADGKLGAFVEVKNSTIG---TGTKVPHLTY----VGDADIGEYS 389 Query: 147 EI 148 I Sbjct: 390 NI 391 Score = 38.7 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 26/112 (23%), Positives = 45/112 (40%), Gaps = 7/112 (6%) Query: 65 IGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAV-----VGDELPGYTFIGCNNIIGH 119 I V +G ++P + + G T++G CV+ VGD G ++ IG Sbjct: 276 IDVDVTIGRDTVIHPGTQLLGRTQIGGRCVVGPDTTLTDVAVGDGASVVRTHGSSSSIGD 335 Query: 120 HAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSSKPSDKTVIGDNNL 171 A VG L+ +G E++ +I +K T +GD ++ Sbjct: 336 GAAVG-PFTYLRPGTALGADGKLGAFVEVK-NSTIGTGTKVPHLTYVGDADI 385 Score = 35.3 bits (79), Expect = 0.034, Method: Composition-based stats. Identities = 18/100 (18%), Positives = 33/100 (33%), Gaps = 15/100 (15%) Query: 136 DECFLCIGNNNEIREFCSIHRSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTL 195 D I + I IH ++ +T IG C +G + + Sbjct: 270 DPATTWIDVDVTIGRDTVIHPGTQLLGRTQIG------------GRCVVGPDTTLTDVAV 317 Query: 196 LAGHVVVEDNTHTAGASVVHQFCHIGSFAFIGGGSVVSQD 235 G VV + +S + +G F ++ G+ + D Sbjct: 318 GDGASVVRTH---GSSSSIGDGAAVGPFTYLRPGTALGAD 354 Score = 34.5 bits (77), Expect = 0.075, Method: Composition-based stats. Identities = 20/133 (15%), Positives = 41/133 (30%), Gaps = 11/133 (8%) Query: 64 TIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVVGDELPGYTFIGCNNIIGHHAVV 123 + + G ++ + + +G V+ G +L G T IG ++G + Sbjct: 257 VVAAHQLAGVTVVDPATTWIDVDVTIGRDTVIHPGT----QLLGRTQIGGRCVVGPDTTL 312 Query: 124 GVKCQDLKYK--HGDECFLCIGNNNEIREFCSIHRSSKPSDKTVIG-----DNNLIMGSC 176 IG+ + F + + +G N+ I Sbjct: 313 TDVAVGDGASVVRTHGSSSSIGDGAAVGPFTYLRPGTALGADGKLGAFVEVKNSTIGTGT 372 Query: 177 HIAHDCKIGDRNI 189 + H +GD +I Sbjct: 373 KVPHLTYVGDADI 385 >6F1T-V nrPDB Length = 182 Score = 43.7 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 35/172 (20%), Positives = 66/172 (38%), Gaps = 30/172 (17%) Query: 69 VKLGNGCKLYPSSHVFG--NTELGESCVLMTGAVVGDELPGYTFIGCNNIIGHHAVVGVK 126 ++ +G K+ S + G N L ++M ++ +L +G + ++ +V+ + Sbjct: 14 IETASGNKVSRQSVLCGSQNIVLNGKTIVMNDCIIRGDL-ANVRVGRHCVVKSRSVI--R 70 Query: 127 CQDLKYKHG-DECFLCIGNNNEIREFCSIHRSSKPSDKTVIGDNNLIMGSCHIAHDCKIG 185 K+ G L IG++ I E C ++ IG H+ +C IG Sbjct: 71 PPFKKFSKGVAFFPLHIGDHVFIEEDCVVN-------AAQIGS------YVHVGKNCVIG 117 Query: 186 DRNIFANNTLLAGHVVVEDNTHTAGASVVHQFCHIGSFAFIGGGSVVSQDVP 237 R + + + DNT +VV F F G + S ++P Sbjct: 118 RRCVLKDCCK------ILDNTVLPPETVVPPFT-----VFSGCPGLFSGELP 158 Score = 36.4 bits (82), Expect = 0.019, Method: Composition-based stats. Identities = 13/60 (21%), Positives = 22/60 (36%), Gaps = 1/60 (1%) Query: 41 IHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAV 100 I + + V+ +G Y +G + +G C L + NT L V+ V Sbjct: 87 IGDHVFIEEDCVVNA-AQIGSYVHVGKNCVIGRRCVLKDCCKILDNTVLPPETVVPPFTV 145 Score = 34.1 bits (76), Expect = 0.086, Method: Composition-based stats. Identities = 18/57 (31%), Positives = 25/57 (43%), Gaps = 1/57 (1%) Query: 39 VLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVL 95 V I VV+ A IG V VG C IG L + CK+ ++ + T + V Sbjct: 91 VFIEEDCVVN-AAQIGSYVHVGKNCVIGRRCVLKDCCKILDNTVLPPETVVPPFTVF 146 Score = 32.6 bits (72), Expect = 0.22, Method: Composition-based stats. Identities = 21/112 (18%), Positives = 36/112 (32%), Gaps = 24/112 (21%) Query: 55 KGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVVGDELPGYTFIGCN 114 V VG +C + S + K + F +G+ + VV Sbjct: 53 ANVRVGRHCVVKSRSVIRPPFKKFSKGVAFFPLHIGDHVFIEEDCVVNAA---------- 102 Query: 115 NIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSSKPSDKTVI 166 IG + VG C IG +++ C I ++ +TV+ Sbjct: 103 -QIGSYVHVGKNC-------------VIGRRCVLKDCCKILDNTVLPPETVV 140 Score = 32.2 bits (71), Expect = 0.35, Method: Composition-based stats. Identities = 14/54 (25%), Positives = 22/54 (40%), Gaps = 5/54 (9%) Query: 53 IGKGVSVGPYCT-----IGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVV 101 IG V + C IGS V +G C + + ++ ++ VL VV Sbjct: 87 IGDHVFIEEDCVVNAAQIGSYVHVGKNCVIGRRCVLKDCCKILDNTVLPPETVV 140 >5NW4-h nrPDB Length = 222 Score = 43.7 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 35/172 (20%), Positives = 66/172 (38%), Gaps = 30/172 (17%) Query: 69 VKLGNGCKLYPSSHVFG--NTELGESCVLMTGAVVGDELPGYTFIGCNNIIGHHAVVGVK 126 ++ +G K+ S + G N L ++M ++ +L +G + ++ +V+ + Sbjct: 54 IETASGNKVSRQSVLCGSQNIVLNGKTIVMNDCIIRGDL-ANVRVGRHCVVKSRSVI--R 110 Query: 127 CQDLKYKHG-DECFLCIGNNNEIREFCSIHRSSKPSDKTVIGDNNLIMGSCHIAHDCKIG 185 K+ G L IG++ I E C ++ IG H+ +C IG Sbjct: 111 PPFKKFSKGVAFFPLHIGDHVFIEEDCVVN-------AAQIGS------YVHVGKNCVIG 157 Query: 186 DRNIFANNTLLAGHVVVEDNTHTAGASVVHQFCHIGSFAFIGGGSVVSQDVP 237 R + + + DNT +VV F F G + S ++P Sbjct: 158 RRCVLKDCCK------ILDNTVLPPETVVPPFT-----VFSGCPGLFSGELP 198 Score = 36.4 bits (82), Expect = 0.019, Method: Composition-based stats. Identities = 13/60 (21%), Positives = 22/60 (36%), Gaps = 1/60 (1%) Query: 41 IHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAV 100 I + + V+ +G Y +G + +G C L + NT L V+ V Sbjct: 127 IGDHVFIEEDCVVNA-AQIGSYVHVGKNCVIGRRCVLKDCCKILDNTVLPPETVVPPFTV 185 Score = 34.1 bits (76), Expect = 0.086, Method: Composition-based stats. Identities = 18/57 (31%), Positives = 25/57 (43%), Gaps = 1/57 (1%) Query: 39 VLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVL 95 V I VV+ A IG V VG C IG L + CK+ ++ + T + V Sbjct: 131 VFIEEDCVVN-AAQIGSYVHVGKNCVIGRRCVLKDCCKILDNTVLPPETVVPPFTVF 186 Score = 32.6 bits (72), Expect = 0.22, Method: Composition-based stats. Identities = 21/112 (18%), Positives = 36/112 (32%), Gaps = 24/112 (21%) Query: 55 KGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVVGDELPGYTFIGCN 114 V VG +C + S + K + F +G+ + VV Sbjct: 93 ANVRVGRHCVVKSRSVIRPPFKKFSKGVAFFPLHIGDHVFIEEDCVVNAA---------- 142 Query: 115 NIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSSKPSDKTVI 166 IG + VG C IG +++ C I ++ +TV+ Sbjct: 143 -QIGSYVHVGKNC-------------VIGRRCVLKDCCKILDNTVLPPETVV 180 Score = 32.2 bits (71), Expect = 0.35, Method: Composition-based stats. Identities = 14/54 (25%), Positives = 22/54 (40%), Gaps = 5/54 (9%) Query: 53 IGKGVSVGPYCT-----IGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVV 101 IG V + C IGS V +G C + + ++ ++ VL VV Sbjct: 127 IGDHVFIEEDCVVNAAQIGSYVHVGKNCVIGRRCVLKDCCKILDNTVLPPETVV 180 >6O85-A nrPDB Length = 721 Score = 43.7 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 27/132 (20%), Positives = 52/132 (39%), Gaps = 15/132 (11%) Query: 24 SSSLSYSRED-SRDSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSH 82 + S ++SR + R EV + +++ N ++G G +G C I ++ +G GC + + Sbjct: 332 TQSCTHSRHNIYRGPEVSLGHGSILEENVLLGSGTVIGSNCFI-TNSVIGPGCHIGDNVV 390 Query: 83 VFGNTELGESCVLMTGAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCI 142 + + L G V + + C+N V LK + + + Sbjct: 391 L-------DQTYLWQGVRVAAGAQIHQSLLCDNAEVKERVT------LKPRSVLTSQVVV 437 Query: 143 GNNNEIREFCSI 154 G N + E I Sbjct: 438 GPNITLPEGSVI 449 Score = 33.3 bits (74), Expect = 0.13, Method: Composition-based stats. Identities = 24/117 (20%), Positives = 35/117 (29%), Gaps = 16/117 (13%) Query: 143 GNNNEIREFCSIHRSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVV 202 G + + + TVIG N I S I C IGD + L G Sbjct: 345 GPEVSLGHGSILEENVLLGSGTVIGSNCFITNSV-IGPGCHIGDNVVLDQTYLWQG---- 399 Query: 203 EDNTHTAGASVVHQF-----CHIGSFAFIGGGSVVSQDV---PKYMMVAGERAELRG 251 A + +HQ + + SV++ V P + G L Sbjct: 400 ---VRVAAGAQIHQSLLCDNAEVKERVTLKPRSVLTSQVVVGPNITLPEGSVISLHP 453 >3F1X-A nrPDB Length = 310 Score = 43.4 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 21/108 (19%), Positives = 43/108 (39%), Gaps = 9/108 (8%) Query: 137 ECFLCIGNNNEIREFCSIHRSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANN--- 193 E + I +I +I + VIG ++I + + +G ++ +N Sbjct: 188 ETGIDIHPGAQIGHHFTIDHGT----GVVIGATSIIGNNVKLYQGVTLGAKSFPLDNNGN 243 Query: 194 --TLLAGHVVVEDNTHTAGASVVHQFCHIGSFAFIGGGSVVSQDVPKY 239 + H ++ED+ + + IG A +GG V+++VP Sbjct: 244 PIKGIPRHPILEDDVIVYSNATILGRVTIGKGATVGGNIWVTENVPAG 291 Score = 36.8 bits (83), Expect = 0.015, Method: Composition-based stats. Identities = 16/106 (15%), Positives = 34/106 (32%), Gaps = 18/106 (16%) Query: 47 VHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCV-LMTGAVVGDEL 105 +HP A IG ++ G+ V +G + + ++ LG L + Sbjct: 193 IHPGAQIGHHFTIDH----GTGVVIGATSIIGNNVKLYQGVTLGAKSFPLDNNGNPIKGI 248 Query: 106 PGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREF 151 P + + + I+ +A + + IG + Sbjct: 249 PRHPILEDDVIVYSNATI-------------LGRVTIGKGATVGGN 281 >3EG4-A nrPDB Length = 304 Score = 42.6 bits (98), Expect = 3e-04, Method: Composition-based stats. Identities = 22/118 (18%), Positives = 42/118 (35%), Gaps = 21/118 (17%) Query: 154 IHRSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASV 213 + + + +G I + H++ IG + AG ++EDN S Sbjct: 161 VDKGAMIDTWATVGSCAQIGKNVHLSGGVGIGG----VLEPMQAGPTIIEDNCFIGARSE 216 Query: 214 VHQFCHIGSFAFIGGGSVVSQ---------------DVPKYMMVAGERAELRGLNLEG 256 V + C + + +G G + + +VP Y +V + G N+ G Sbjct: 217 VVEGCIVREGSVLGMGVFIGKSTKIVDRATGEVFYGEVPPYSVVVA--GTMPGKNVPG 272 Score = 36.0 bits (81), Expect = 0.024, Method: Composition-based stats. Identities = 25/116 (21%), Positives = 41/116 (35%), Gaps = 18/116 (15%) Query: 45 AVVHPNAVIGKGVSVGPYCTIGSSVKLGNG--------------CKLYPSSHVFGNTELG 90 A V A+I +VG IG +V L G + + + +E+ Sbjct: 159 AYVDKGAMIDTWATVGSCAQIGKNVHLSGGVGIGGVLEPMQAGPTIIEDNCFIGARSEVV 218 Query: 91 ESCVLMTGAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNN 146 E C++ G+V+G + FIG + I A V ++ G N Sbjct: 219 EGCIVREGSVLGMGV----FIGKSTKIVDRATGEVFYGEVPPYSVVVAGTMPGKNV 270 Score = 35.3 bits (79), Expect = 0.038, Method: Composition-based stats. Identities = 18/84 (21%), Positives = 29/84 (34%), Gaps = 20/84 (23%) Query: 36 DSEVLIHPSAVVHPNAVIGKGV--------------------SVGPYCTIGSSVKLGNGC 75 D +I A V A IGK V + C IG+ ++ GC Sbjct: 162 DKGAMIDTWATVGSCAQIGKNVHLSGGVGIGGVLEPMQAGPTIIEDNCFIGARSEVVEGC 221 Query: 76 KLYPSSHVFGNTELGESCVLMTGA 99 + S + +G+S ++ A Sbjct: 222 IVREGSVLGMGVFIGKSTKIVDRA 245 Score = 34.1 bits (76), Expect = 0.087, Method: Composition-based stats. Identities = 22/131 (16%), Positives = 42/131 (32%), Gaps = 22/131 (16%) Query: 43 PSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVVG 102 P+ +V +A I + P + + G + + V ++G++ L G +G Sbjct: 134 PNCIVRHSAYIAPNAILMP-SFVNLGAYVDKGAMIDTWATVGSCAQIGKNVHLSGGVGIG 192 Query: 103 DELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSSKPSD 162 L +D + IG +E+ E C + S Sbjct: 193 GVLE------------PMQAGPTIIEDNCF---------IGARSEVVEGCIVREGSVLGM 231 Query: 163 KTVIGDNNLIM 173 IG + I+ Sbjct: 232 GVFIGKSTKIV 242 Score = 32.2 bits (71), Expect = 0.35, Method: Composition-based stats. Identities = 16/73 (21%), Positives = 28/73 (38%), Gaps = 8/73 (10%) Query: 42 HPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNT-------ELGESCV 94 P+ ++ N IG V C + LG G + S+ + E+ V Sbjct: 201 GPT-IIEDNCFIGARSEVVEGCIVREGSVLGMGVFIGKSTKIVDRATGEVFYGEVPPYSV 259 Query: 95 LMTGAVVGDELPG 107 ++ G + G +PG Sbjct: 260 VVAGTMPGKNVPG 272 >6AMZ-A nrPDB Length = 281 Score = 39.9 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 29/148 (19%), Positives = 56/148 (37%), Gaps = 10/148 (6%) Query: 29 YSREDSRDSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTE 88 ++ E + + V + P AV + K V + P + + G + + V + Sbjct: 101 WTEEQFKAAGVRVVPPAVARRGSFQAKNVVLMP-SYVNIGAYVDEGTMVDTWATVGSCAQ 159 Query: 89 LGESCVLMTGAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLC-----IG 143 +G++ L G +G L II + +G + + ++ +E + IG Sbjct: 160 IGKNVHLSGGVGIGGVLEPLQ--ANPTIIEDNCFIGARSEIVEGVIVEEGSVISMGVYIG 217 Query: 144 NNNEI--REFCSIHRSSKPSDKTVIGDN 169 + I RE IH P+ V+ N Sbjct: 218 QSTRIYDRETGEIHYGRVPAGSVVVPGN 245 Score = 34.1 bits (76), Expect = 0.080, Method: Composition-based stats. Identities = 23/138 (16%), Positives = 43/138 (31%), Gaps = 8/138 (5%) Query: 110 FIGCNNIIGHHAVVGVKCQDLKYKH--GDECFLCIGNNNEIREFCSIHRSSKPSDKTVIG 167 F G A V V + + + + + + I + + + +G Sbjct: 98 FSGWTEEQFKAAGVRVVPPAVARRGSFQAKNVVLMPSYVNIGAY--VDEGTMVDTWATVG 155 Query: 168 DNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFCHIGSFAFIG 227 I + H++ IG L A ++EDN S + + + + I Sbjct: 156 SCAQIGKNVHLSGGVGIGG----VLEPLQANPTIIEDNCFIGARSEIVEGVIVEEGSVIS 211 Query: 228 GGSVVSQDVPKYMMVAGE 245 G + Q Y GE Sbjct: 212 MGVYIGQSTRIYDRETGE 229 >3BXY-A nrPDB Length = 285 Score = 39.5 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 26/132 (19%), Positives = 46/132 (34%), Gaps = 6/132 (4%) Query: 43 PSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVVG 102 P A V A I + + P + + G + + V ++G++ L G +G Sbjct: 118 PPAAVRQGAFIARNTVLMP-SYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIG 176 Query: 103 ---DELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEI--REFCSIHRS 157 + L I +N V+ ++ + IG + I RE IH Sbjct: 177 GVLEPLQANPTIIEDNCFIGARSEVVEGVIVEEGSVISMGVYIGQSTRIYDRETGDIHYG 236 Query: 158 SKPSDKTVIGDN 169 P+ V+ N Sbjct: 237 RVPAGSVVVSGN 248 >6I7T-I nrPDB Length = 578 Score = 39.1 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 23/126 (18%), Positives = 46/126 (36%), Gaps = 8/126 (6%) Query: 35 RDSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGN-----GCKLYPSSHVFGNTEL 89 + I A+V P I +V +G+ +G+ G L+P H+ + Sbjct: 422 QIQSAAIGADAIVDPKCQISAHSNV-KMSVLGTQANIGSRCRVAGSLLFPGVHLGDEV-I 479 Query: 90 GESCVLMTGAVVGDELP-GYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEI 148 E+C++ A +G + +I + ++ + Y DE I +++ I Sbjct: 480 LENCIIGPMAKIGSKCKLSNCYIEGHYVVEPKNNFKGETLANVYLDEDEEDELIYDDSVI 539 Query: 149 REFCSI 154 I Sbjct: 540 AGESEI 545 >3GOS-A nrPDB Length = 276 Score = 38.7 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 25/132 (18%), Positives = 46/132 (34%), Gaps = 6/132 (4%) Query: 43 PSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVVG 102 P A V A I + + P + + G + + V ++G++ L G +G Sbjct: 109 PPATVRKGAFIARNTVLMP-SYVNIGAFVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIG 167 Query: 103 ---DELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEI--REFCSIHRS 157 + L I +N V+ ++ + IG + I RE +H Sbjct: 168 GVLEPLQANPTIIEDNCFVGARSEVVEGVIVEEGSVISMGVFIGQSTRIYDRETGEVHYG 227 Query: 158 SKPSDKTVIGDN 169 P+ V+ N Sbjct: 228 RVPAGSVVVSGN 239 Score = 27.6 bits (59), Expect = 7.2, Method: Composition-based stats. Identities = 24/137 (17%), Positives = 45/137 (32%), Gaps = 23/137 (16%) Query: 36 DSEVLIHPSAVVHPNAVIGKGV--------------------SVGPYCTIGSSVKLGNGC 75 D ++ A V A IGK V + C +G+ ++ G Sbjct: 137 DEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIEDNCFVGARSEVVEGV 196 Query: 76 KLYPSSHVFGNTELGESCVLM---TGAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKY 132 + S + +G+S + TG V +P + + N+ + C + Sbjct: 197 IVEEGSVISMGVFIGQSTRIYDRETGEVHYGRVPAGSVVVSGNLPSKDGSYSLYCAVIVK 256 Query: 133 KHGDECFLCIGNNNEIR 149 K + +G N +R Sbjct: 257 KVDAKTRSKVGINELLR 273 >5B04-E nrPDB Length = 458 Score = 38.3 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 26/143 (18%), Positives = 47/143 (32%), Gaps = 21/143 (14%) Query: 96 MTGAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECF------LCIGNNNEIR 149 G + E+ I + II A +L + + + Sbjct: 298 YDGGLSSQEIKINALIAKDGIICSRANNLPNYFELNKCIAKLTPEQRLVDVTVSERALVG 357 Query: 150 EFCSIHRSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTA 209 C ++ + D + I I +C IG + +N+ L+ ++VVED Sbjct: 358 ADCMVNEGTTIKDNSNI-------KKSIIGKNCVIGKGVVVSNSILMD-NIVVEDGVRL- 408 Query: 210 GASVVHQFCHIGSFAFIGGGSVV 232 + C + S A IG S + Sbjct: 409 ------ESCIVASGAQIGAKSKL 425 Score = 36.4 bits (82), Expect = 0.019, Method: Composition-based stats. Identities = 19/107 (17%), Positives = 43/107 (40%), Gaps = 15/107 (14%) Query: 45 AVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVVGDE 104 A + P + V+V +G+ + G + +S++ + +G++CV+ G VV + Sbjct: 337 AKLTPEQRLVD-VTVSERALVGADCMVNEGTTIKDNSNI-KKSIIGKNCVIGKGVVVSNS 394 Query: 105 LPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREF 151 + + + + +V Q IG +++RE Sbjct: 395 ILMDNIVVEDGVRLESCIVASGAQ-------------IGAKSKLREC 428 Score = 33.7 bits (75), Expect = 0.12, Method: Composition-based stats. Identities = 14/80 (17%), Positives = 27/80 (33%), Gaps = 2/80 (2%) Query: 39 VLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTG 98 L+ +V+ I ++ IG + +G G + +S + N + + L + Sbjct: 354 ALVGADCMVNEGTTIKDNSNIKK-SIIGKNCVIGKGVVV-SNSILMDNIVVEDGVRLESC 411 Query: 99 AVVGDELPGYTFIGCNNIIG 118 V G IG Sbjct: 412 IVASGAQIGAKSKLRECEIG 431 >1KGQ-A nrPDB Length = 274 Score = 37.6 bits (85), Expect = 0.008, Method: Composition-based stats. Identities = 25/132 (18%), Positives = 46/132 (34%), Gaps = 6/132 (4%) Query: 43 PSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVVG 102 P A V A I + + P + + G + + V ++G++ L G +G Sbjct: 107 PPATVRQGAFIARNTVLMP-SYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIG 165 Query: 103 ---DELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEI--REFCSIHRS 157 + L I +N V+ ++ + +G + I RE IH Sbjct: 166 GVLEPLQANPTIIEDNCFIGARSEVVEGVIVEEGSVISMGVYLGQSTRIYDRETGEIHYG 225 Query: 158 SKPSDKTVIGDN 169 P+ V+ N Sbjct: 226 RVPAGSVVVSGN 237 >1FWY-A nrPDB Length = 331 Score = 37.2 bits (84), Expect = 0.010, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 35/77 (45%), Gaps = 8/77 (10%) Query: 23 LSSSLSYSREDSRDSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSH 82 L +L++ R+ V I + ++ N +G V +G C I + +G+ C++ P Sbjct: 262 LRGTLTHGRD------VEIDTNVIIEGNVTLGHRVKIGTGCVI-KNSVIGDDCEISPY-T 313 Query: 83 VFGNTELGESCVLMTGA 99 V + L +C + A Sbjct: 314 VVEDANLAAACTIGPFA 330 Score = 33.0 bits (73), Expect = 0.21, Method: Composition-based stats. Identities = 15/53 (28%), Positives = 23/53 (43%), Gaps = 7/53 (13%) Query: 51 AVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVVGD 103 I V + T+G VK+G GC + N+ +G+ C + VV D Sbjct: 272 VEIDTNVIIEGNVTLGHRVKIGTGCVIK-------NSVIGDDCEISPYTVVED 317 Score = 31.8 bits (70), Expect = 0.43, Method: Composition-based stats. Identities = 18/75 (24%), Positives = 28/75 (37%), Gaps = 13/75 (17%) Query: 156 RSSKPSD-KTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVV 214 R + I N +I G+ + H KIG + N+ + D+ + +VV Sbjct: 263 RGTLTHGRDVEIDTNVIIEGNVTLGHRVKIGTGCVIKNSV-------IGDDCEISPYTVV 315 Query: 215 HQ-----FCHIGSFA 224 C IG FA Sbjct: 316 EDANLAAACTIGPFA 330 Score = 28.7 bits (62), Expect = 3.6, Method: Composition-based stats. Identities = 11/46 (23%), Positives = 18/46 (39%), Gaps = 3/46 (6%) Query: 200 VVVEDNTHTAGASVVHQFCHIGSFAFIGGGSVVSQD--VPKYMMVA 243 V ++ N G + IG+ I SV+ D + Y +V Sbjct: 272 VEIDTNVIIEGNVTLGHRVKIGTGCVIK-NSVIGDDCEISPYTVVE 316 >6CKT-A nrPDB Length = 284 Score = 36.4 bits (82), Expect = 0.018, Method: Composition-based stats. Identities = 24/135 (17%), Positives = 44/135 (32%), Gaps = 8/135 (5%) Query: 113 CNNIIGHHAVVGVKCQDLKYKHG--DECFLCIGNNNEIREFCSIHRSSKPSDKTVIGDNN 170 C+N + V V + + + + + + I + I +G Sbjct: 101 CSNEQFQQSGVRVVPHAMVRRGAYIAKNTVLMPSYVNIGAY--IDEGVMVDTWATVGSCA 158 Query: 171 LIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFCHIGSFAFIGGGS 230 I + HI+ IG L A ++EDN S + + + + I G Sbjct: 159 QIGKNVHISGGAGIGG----VLEPLQANPTIIEDNCFIGARSEIVEGVIVEKNSVISMGV 214 Query: 231 VVSQDVPKYMMVAGE 245 + Q Y + GE Sbjct: 215 FLGQSTKIYNRITGE 229 Score = 36.0 bits (81), Expect = 0.025, Method: Composition-based stats. Identities = 18/84 (21%), Positives = 30/84 (35%), Gaps = 8/84 (9%) Query: 36 DSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGS--------SVKLGNGCKLYPSSHVFGNT 87 D V++ A V A IGK V + IG + + C + S + Sbjct: 143 DEGVMVDTWATVGSCAQIGKNVHISGGAGIGGVLEPLQANPTIIEDNCFIGARSEIVEGV 202 Query: 88 ELGESCVLMTGAVVGDELPGYTFI 111 + ++ V+ G +G Y I Sbjct: 203 IVEKNSVISMGVFLGQSTKIYNRI 226 Score = 33.0 bits (73), Expect = 0.20, Method: Composition-based stats. Identities = 14/85 (16%), Positives = 31/85 (36%), Gaps = 10/85 (11%) Query: 45 AVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYP--------SSHVFGNTELGESCVLM 96 A + ++ +VG IG +V + G + + + N +G ++ Sbjct: 140 AYIDEGVMVDTWATVGSCAQIGKNVHISGGAGIGGVLEPLQANPTIIEDNCFIGARSEIV 199 Query: 97 TGAVVGDE--LPGYTFIGCNNIIGH 119 G +V + F+G + I + Sbjct: 200 EGVIVEKNSVISMGVFLGQSTKIYN 224 >6EZO-E nrPDB Length = 452 Score = 34.9 bits (78), Expect = 0.047, Method: Composition-based stats. Identities = 26/155 (16%), Positives = 55/155 (35%), Gaps = 15/155 (9%) Query: 18 STIRRLSSSLSYSREDSRDSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKL 77 S + L + +R+ + L VH +A I VG IG ++G + Sbjct: 311 SRVSTLGLYMEANRQVPKLLSALCPEEPPVHSSAQIVSKHLVGVDSLIGPETQIGEKSSI 370 Query: 78 YPSSHVFGNTELGESCVLMTGAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDE 137 S +G SC++ + + L + +V+ C + + G + Sbjct: 371 KRSV-------IGSSCLIKDRVTITNCLLMNSVTVEEGSNIQGSVI---CNNAVIEKGAD 420 Query: 138 CFLCIGNNNEIREFCSIHRSSKPSDKTVIGDNNLI 172 + I I +K ++ ++G++ L+ Sbjct: 421 IK-----DCLIGSGQRIEAKAKRVNEVIVGNDQLM 450 >3TK8-A nrPDB Length = 316 Score = 34.1 bits (76), Expect = 0.088, Method: Composition-based stats. Identities = 29/148 (19%), Positives = 55/148 (37%), Gaps = 8/148 (5%) Query: 28 SYSREDSRDSEVLIHPSAVVHPNAVIGKGVSVGP-YCTIGSSVKLGNGCKLYPSSHVFGN 86 +Y+ ED + P A+ + I K V + P Y IG + G + + V Sbjct: 135 NYTAEDFAAGGFRVVPPAIARRGSFIAKNVVLMPSYTNIG--AYVDEGTMVDTWATVGSC 192 Query: 87 TELGESCVLMTGAVVG---DELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIG 143 ++G++ L G +G + L I +N V+ ++ + +G Sbjct: 193 AQIGKNVHLSGGVGIGGVLEPLQANPVIIEDNCFIGARSEVVEGVIVEENSVISMGVYLG 252 Query: 144 NNNEI--REFCSIHRSSKPSDKTVIGDN 169 + +I RE + P+ V+ N Sbjct: 253 QSTKIYDRETGEVTYGRIPAGSVVVAGN 280 Score = 27.9 bits (60), Expect = 6.9, Method: Composition-based stats. Identities = 26/137 (18%), Positives = 46/137 (33%), Gaps = 23/137 (16%) Query: 36 DSEVLIHPSAVVHPNAVIGKGV--------------------SVGPYCTIGSSVKLGNGC 75 D ++ A V A IGK V + C IG+ ++ G Sbjct: 178 DEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPVIIEDNCFIGARSEVVEGV 237 Query: 76 KLYPSSHVFGNTELGESCVLM---TGAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKY 132 + +S + LG+S + TG V +P + + N+ + C + Sbjct: 238 IVEENSVISMGVYLGQSTKIYDRETGEVTYGRIPAGSVVVAGNLPAKDGTHSLYCAVIVK 297 Query: 133 KHGDECFLCIGNNNEIR 149 K + +G N +R Sbjct: 298 KVDAKTRAKVGLNELLR 314 Score = 27.6 bits (59), Expect = 7.2, Method: Composition-based stats. Identities = 20/100 (20%), Positives = 33/100 (33%), Gaps = 6/100 (6%) Query: 146 NEIREFCSIHRSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDN 205 I + + + +G I + H++ IG L A V++EDN Sbjct: 171 TNIGAY--VDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGG----VLEPLQANPVIIEDN 224 Query: 206 THTAGASVVHQFCHIGSFAFIGGGSVVSQDVPKYMMVAGE 245 S V + + + I G + Q Y GE Sbjct: 225 CFIGARSEVVEGVIVEENSVISMGVYLGQSTKIYDRETGE 264 >2RIJ-A nrPDB Length = 387 Score = 33.7 bits (75), Expect = 0.10, Method: Composition-based stats. Identities = 21/149 (14%), Positives = 47/149 (31%), Gaps = 11/149 (7%) Query: 144 NNNEIREFCSIHRSSKPSDKTVIGDNNLIMG-SCHIAHDC----KIGDRNIFANNTLLAG 198 +N I E + + + T I + + C +I I + + G Sbjct: 216 DNTRILESSKVRMGASLAAGTTIMPGASYVNFNAGTTGACMVEGRISSSAIVGEGSDVGG 275 Query: 199 HVVVEDNTHTAGASVVHQFCHIGSFAFIGGGSVVSQDVPKYMMVAGERAELRGLNLEGLR 258 + + + +G +G SV + +V A L G L Sbjct: 276 GASILGVLSGTSGNAI----SVGKACLLGANSVTGIPLGDNCIVDAGIAVLEGTKF--LL 329 Query: 259 RNGFTMSEMKSLRAAYRKIFMSTETVSLS 287 ++ ++++ ++I+ E L+ Sbjct: 330 KDAEELAKLNPYFNFDKEIYKGLELKGLN 358 >2WLD-A nrPDB Length = 215 Score = 30.6 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 17/126 (13%), Positives = 39/126 (30%), Gaps = 22/126 (17%) Query: 53 IGKGVSV-GPYCTIGSSVK--LGNGCKLYPSSHVFGN---TELGESCVLMTGAVVGDELP 106 I V + G C++ S + + +G+ C+L G + + Sbjct: 61 IADDVEIMGLVCSLHSDCSLQIQAKTTMGNGEITIAEKGKISIGKDCMLAHGYEIRNTDM 120 Query: 107 GYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSSKPSDKTVI 166 + N +H + IGN+ + +I + + V+ Sbjct: 121 HPIYSLENGERINHGK----------------DVIIGNHVWLGRNVTILKGVCIPNNVVV 164 Query: 167 GDNNLI 172 G + ++ Sbjct: 165 GSHTVL 170 >5E3R-A nrPDB Length = 302 Score = 29.1 bits (63), Expect = 2.7, Method: Composition-based stats. Identities = 12/69 (17%), Positives = 22/69 (31%), Gaps = 4/69 (5%) Query: 154 IHRSSKPSDKTVIGDNNLIMGSCHIA--HDCKIGDRNIFANNTLLAGHVVVEDNTHTAGA 211 I D T +G IMG+ H +G R + N+ + + D+ Sbjct: 183 ISAGVTVDDGTDVGGGASIMGTLSGGGQHVISLGKRCLLGANSGCG--IPLGDDCIIEAG 240 Query: 212 SVVHQFCHI 220 + + Sbjct: 241 LYITAGTKV 249 >6C5V-A nrPDB Length = 697 Score = 29.1 bits (63), Expect = 2.9, Method: Composition-based stats. Identities = 11/47 (23%), Positives = 25/47 (53%) Query: 247 AELRGLNLEGLRRNGFTMSEMKSLRAAYRKIFMSTETVSLSFEERLT 293 A++ GL+ E L R ++ S+ Y+ I+ ++ T+ ++ E + Sbjct: 52 AKVPGLSPEALWREANVTEDLASMLNRYKLIYKTSGTLGIALAEPVD 98 >3R5A-A nrPDB Length = 347 Score = 28.3 bits (61), Expect = 5.3, Method: Composition-based stats. Identities = 23/130 (17%), Positives = 38/130 (29%), Gaps = 33/130 (25%) Query: 46 VVHPNAVIGKGVSVGPYCTIGSSVKL-------------GNG---CKLYPSSHVFGNTEL 89 VV I V IG + G G ++ V ++L Sbjct: 180 VVPAGVRIADTARVRLGAYIGEGTTVMHEGFVNFNAGTEGPGMIEGRVSAGVFVGKGSDL 239 Query: 90 GESCVLMTGAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIR 149 G C M G + +G +IG +A +G+ +G+ N + Sbjct: 240 GGGCSTMGTLSGGGNIV--ISVGEGCLIGANAGIGIP---------------LGDRNIVE 282 Query: 150 EFCSIHRSSK 159 I +K Sbjct: 283 AGLYITAGTK 292 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.115 0.272 Lambda K H 0.267 0.0355 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,115,125 Number of Sequences: 36641 Number of extensions: 360365 Number of successful extensions: 2179 Number of sequences better than 10.0: 79 Number of HSP's better than 10.0 without gapping: 102 Number of HSP's successfully gapped in prelim test: 38 Number of HSP's that attempted gapping in prelim test: 995 Number of HSP's gapped (non-prelim): 489 length of query: 336 length of database: 10,336,785 effective HSP length: 98 effective length of query: 238 effective length of database: 6,745,967 effective search space: 1605540146 effective search space used: 1605540146 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.5 bits) S2: 59 (27.5 bits)