BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9SD76 (841 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4BQE-A nrPDB 1745 0.0 5OX0-A nrPDB 699 0.0 1YGP-A nrPDB 690 0.0 5IKP-A nrPDB 680 0.0 2ZB2-A nrPDB 670 0.0 1AHP-A nrPDB 624 e-179 2C4M-A nrPDB 620 e-178 5LR8-A nrPDB 577 e-165 4L22-A nrPDB 460 e-129 2O57-A nrPDB 33 0.67 4UOQ-A nrPDB 31 2.2 4KS7-A nrPDB 31 2.6 5I2T-A nrPDB 31 2.6 5WLC-LO nrPDB 31 2.7 1KG4-A nrPDB 30 3.3 1OFH-G nrPDB 30 3.5 1KA0-A nrPDB 30 6.1 >4BQE-A nrPDB Length = 874 Score = 1745 bits (4520), Expect = 0.0, Method: Compositional matrix adjust. Identities = 841/841 (100%), Positives = 841/841 (100%) Query: 1 MANANGKAATSLPEKISAKANPEADDATEIAGNIVYHAKYSPHFSPLKFGPEQALYATAE 60 MANANGKAATSLPEKISAKANPEADDATEIAGNIVYHAKYSPHFSPLKFGPEQALYATAE Sbjct: 34 MANANGKAATSLPEKISAKANPEADDATEIAGNIVYHAKYSPHFSPLKFGPEQALYATAE 93 Query: 61 SLRDRLIQLWNETYVHFNKVDPKQTYYLSMEYLQGRALTNAIGNLNLQGPYADALRTLGY 120 SLRDRLIQLWNETYVHFNKVDPKQTYYLSMEYLQGRALTNAIGNLNLQGPYADALRTLGY Sbjct: 94 SLRDRLIQLWNETYVHFNKVDPKQTYYLSMEYLQGRALTNAIGNLNLQGPYADALRTLGY 153 Query: 121 ELEEIAEQEKDAALGNGGLGRLASCFLDSMATLNLPAWGYGLRYRHGLFKQIITKKGQEE 180 ELEEIAEQEKDAALGNGGLGRLASCFLDSMATLNLPAWGYGLRYRHGLFKQIITKKGQEE Sbjct: 154 ELEEIAEQEKDAALGNGGLGRLASCFLDSMATLNLPAWGYGLRYRHGLFKQIITKKGQEE 213 Query: 181 IPEDWLEKFSPWEIVRHDVVFPVRFFGKVQVNPDGSRKWVDGDVVQALAYDVPIPGYGTK 240 IPEDWLEKFSPWEIVRHDVVFPVRFFGKVQVNPDGSRKWVDGDVVQALAYDVPIPGYGTK Sbjct: 214 IPEDWLEKFSPWEIVRHDVVFPVRFFGKVQVNPDGSRKWVDGDVVQALAYDVPIPGYGTK 273 Query: 241 NTISLRLWEAKARAEDLDLFQFNEGEYELAAQLHSRAQQICTVLYPGDATENGKLLRLKQ 300 NTISLRLWEAKARAEDLDLFQFNEGEYELAAQLHSRAQQICTVLYPGDATENGKLLRLKQ Sbjct: 274 NTISLRLWEAKARAEDLDLFQFNEGEYELAAQLHSRAQQICTVLYPGDATENGKLLRLKQ 333 Query: 301 QFFLCSASLQDIISRFHERSTTEGSRKWSEFPSKVAVQMNDTHPTLAIPELMRLLMDDNG 360 QFFLCSASLQDIISRFHERSTTEGSRKWSEFPSKVAVQMNDTHPTLAIPELMRLLMDDNG Sbjct: 334 QFFLCSASLQDIISRFHERSTTEGSRKWSEFPSKVAVQMNDTHPTLAIPELMRLLMDDNG 393 Query: 361 LGWDEAWDVTSKTVAYTNHTVLPEALEKWSQSLMWKLLPRHMEIIEEIDKRFVQTIRDTR 420 LGWDEAWDVTSKTVAYTNHTVLPEALEKWSQSLMWKLLPRHMEIIEEIDKRFVQTIRDTR Sbjct: 394 LGWDEAWDVTSKTVAYTNHTVLPEALEKWSQSLMWKLLPRHMEIIEEIDKRFVQTIRDTR 453 Query: 421 VDLEDKISSLSILDNNPQKPVVRMANLCVVSSHTVNGVAQLHSDILKAELFADYVSIWPN 480 VDLEDKISSLSILDNNPQKPVVRMANLCVVSSHTVNGVAQLHSDILKAELFADYVSIWPN Sbjct: 454 VDLEDKISSLSILDNNPQKPVVRMANLCVVSSHTVNGVAQLHSDILKAELFADYVSIWPN 513 Query: 481 KFQNKTNGITPRRWLRFCSPELSDIITKWLKTDKWITDLDLLTGLRQFADNEELQSEWAS 540 KFQNKTNGITPRRWLRFCSPELSDIITKWLKTDKWITDLDLLTGLRQFADNEELQSEWAS Sbjct: 514 KFQNKTNGITPRRWLRFCSPELSDIITKWLKTDKWITDLDLLTGLRQFADNEELQSEWAS 573 Query: 541 AKTANKKRLAQYIERVTGVSIDPTSLFDIQVKRIHEYKRQLMNILGVVYRFKKLKEMKPE 600 AKTANKKRLAQYIERVTGVSIDPTSLFDIQVKRIHEYKRQLMNILGVVYRFKKLKEMKPE Sbjct: 574 AKTANKKRLAQYIERVTGVSIDPTSLFDIQVKRIHEYKRQLMNILGVVYRFKKLKEMKPE 633 Query: 601 ERKKTVPRTVMIGGKAFATYTNAKRIVKLVNDVGDVVNSDPEVNEYLKVVFVPNYNVTVA 660 ERKKTVPRTVMIGGKAFATYTNAKRIVKLVNDVGDVVNSDPEVNEYLKVVFVPNYNVTVA Sbjct: 634 ERKKTVPRTVMIGGKAFATYTNAKRIVKLVNDVGDVVNSDPEVNEYLKVVFVPNYNVTVA 693 Query: 661 EMLIPGSELSQHISTAGMEASGTSNMKFALNGCLIIGTLDGANVEIREEVGEENFFLFGA 720 EMLIPGSELSQHISTAGMEASGTSNMKFALNGCLIIGTLDGANVEIREEVGEENFFLFGA Sbjct: 694 EMLIPGSELSQHISTAGMEASGTSNMKFALNGCLIIGTLDGANVEIREEVGEENFFLFGA 753 Query: 721 TADQVPRLRKEREDGLFKPDPRFEEAKQFVKSGVFGSYDYGPLLDSLEGNTGFGRGDYFL 780 TADQVPRLRKEREDGLFKPDPRFEEAKQFVKSGVFGSYDYGPLLDSLEGNTGFGRGDYFL Sbjct: 754 TADQVPRLRKEREDGLFKPDPRFEEAKQFVKSGVFGSYDYGPLLDSLEGNTGFGRGDYFL 813 Query: 781 VGYDFPSYMDAQAKVDEAYKDRKGWLKMSILSTAGSGKFSSDRTIAQYAKEIWNIEACPV 840 VGYDFPSYMDAQAKVDEAYKDRKGWLKMSILSTAGSGKFSSDRTIAQYAKEIWNIEACPV Sbjct: 814 VGYDFPSYMDAQAKVDEAYKDRKGWLKMSILSTAGSGKFSSDRTIAQYAKEIWNIEACPV 873 Query: 841 P 841 P Sbjct: 874 P 874 >5OX0-A nrPDB Length = 843 Score = 699 bits (1805), Expect = 0.0, Method: Compositional matrix adjust. Identities = 392/834 (47%), Positives = 526/834 (63%), Gaps = 27/834 (3%) Query: 14 EKISAKANPEADDATEIAGNIVYHAKYSPHFSPLK----FGPEQALYATAESLRDRLIQL 69 ++IS + ++ TE+ N H HF+ +K P +A A ++RD L+ Sbjct: 12 KQISVRGLAGVENVTELKKNFNRHL----HFTLVKDRNVATPRDYYFALAHTVRDHLVGR 67 Query: 70 WNETYVHFNKVDPKQTYYLSMEYLQGRALTNAIGNLNLQGPYADALRTLGYELEEIAEQE 129 W T H+ + DPK+ YYLS+E+ GR L N + NL L+ +A LG ++EE+ E E Sbjct: 68 WIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIE 127 Query: 130 KDAALGNGGLGRLASCFLDSMATLNLPAWGYGLRYRHGLFKQIITKKGQEEIPEDWLEKF 189 +DA LGNGGLGRLA+CFLDSMATL L A+GYG+RY G+F Q I Q E +DWL Sbjct: 128 EDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYG 187 Query: 190 SPWEIVRHDVVFPVRFFGKVQVNPDGSRKWVDGDVVQALAYDVPIPGYGTKNTISLRLWE 249 +PWE R + PV F+G+V+ G+ KWVD VV A+ YD P+PGY ++RLW Sbjct: 188 NPWEKARPEFTLPVHFYGRVEHTSQGA-KWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWS 246 Query: 250 AKARAEDLDLFQFNEGEYELAAQLHSRAQQICTVLYPGDATENGKLLRLKQQFFLCSASL 309 AKA D +L FN G Y A + A+ I VLYP D GK LRLKQ++F+ +A+L Sbjct: 247 AKA-PNDFNLKDFNVGGYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATL 305 Query: 310 QDIISRFHERSTTEGSR-----KWSEFPSKVAVQMNDTHPTLAIPELMRLLMDDNGLGWD 364 QDII RF +S+ G R + FP KVA+Q+NDTHP+LAIPELMR+L+D L WD Sbjct: 306 QDIIRRF--KSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWD 363 Query: 365 EAWDVTSKTVAYTNHTVLPEALEKWSQSLMWKLLPRHMEIIEEIDKRFVQTIRDTRVDLE 424 +AW+VT KT AYTNHTVLPEALE+W L+ LLPRH++II EI++RF+ + Sbjct: 364 KAWEVTVKTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDV 423 Query: 425 DKISSLSILDNNPQKPVVRMANLCVVSSHTVNGVAQLHSDILKAELFADYVSIWPNKFQN 484 D++ +S+++ K + MA+LC+ SH VNGVA++HS+ILK +F D+ + P+KFQN Sbjct: 424 DRLRRMSLVEEGAVKRI-NMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQN 482 Query: 485 KTNGITPRRWLRFCSPELSDIITKWLKTDKWITDLDLLTGLRQFADNEELQSEWASAKTA 544 KTNGITPRRWL C+P L++II + + +++I+DLD L L + D+E + A K Sbjct: 483 KTNGITPRRWLVLCNPGLAEIIAERI-GEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQE 541 Query: 545 NKKRLAQYIERVTGVSIDPTSLFDIQVKRIHEYKRQLMNILGVVYRFKKLKEMKPEERKK 604 NK + A Y+ER V I+P SLFD+QVKRIHEYKRQL+N L V+ + ++K+ E K Sbjct: 542 NKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKK---EPNKF 598 Query: 605 TVPRTVMIGGKAFATYTNAKRIVKLVNDVGDVVNSDPEVNEYLKVVFVPNYNVTVAEMLI 664 VPRTVMIGGKA Y AK I+KL+ +GDVVN DP V + L+V+F+ NY V++AE +I Sbjct: 599 VVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVI 658 Query: 665 PGSELSQHISTAGMEASGTSNMKFALNGCLIIGTLDGANVEIREEVGEENFFLFGATADQ 724 P ++LS+ ISTAG EASGT NMKF LNG L IGT+DGANVE+ EE GEENFF+FG + Sbjct: 659 PAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVED 718 Query: 725 VPRL--RKEREDGLFKPDPRFEEAKQFVKSGVFGSYDYGPLLDSLEGNTGFGRGDYFLVG 782 V RL R + P + + + SG F D + D F V Sbjct: 719 VDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIV---NMLMHHDRFKVF 775 Query: 783 YDFPSYMDAQAKVDEAYKDRKGWLKMSILSTAGSGKFSSDRTIAQYAKEIWNIE 836 D+ Y+ Q +V YK+ + W +M I + A SGKFSSDRTIAQYA+EIW +E Sbjct: 776 ADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVE 829 >1YGP-A nrPDB Length = 879 Score = 690 bits (1780), Expect = 0.0, Method: Compositional matrix adjust. Identities = 382/822 (46%), Positives = 525/822 (63%), Gaps = 52/822 (6%) Query: 54 ALYATAESLRDRLIQLWNETYVHFNKVDPKQTYYLSMEYLQGRALTNAIGNLNLQGP--- 110 A A + S+RD L+ WN+T F DPK+ YYLS+E+L GRAL NA+ N+ ++ P Sbjct: 68 AYEAASMSIRDNLVIDWNKTQQKFTTRDPKRVYYLSLEFLMGRALDNALINMKIEDPEDP 127 Query: 111 ----------YADALRTLGYELEEIAEQEKDAALGNGGLGRLASCFLDSMATLNLPAWGY 160 AL LG++LE++ +QE DA LGNGGLGRLA+CF+DSMAT +PAWGY Sbjct: 128 AASKGKPREMIKGALDELGFKLEDVLDQEPDAGLGNGGLGRLAACFVDSMATEGIPAWGY 187 Query: 161 GLRYRHGLFKQIITKKGQEEIPEDWLEKFSPWEIVRHDVVFPVRFFGKVQVNPDGSR--- 217 GLRY +G+F Q I Q E P+ WL +PWEI R++V PV F+G V P+G + Sbjct: 188 GLRYEYGIFAQKIIDGYQVETPDYWLNSGNPWEIERNEVQIPVTFYGYVD-RPEGGKTTL 246 Query: 218 ---KWVDGDVVQALAYDVPIPGYGTKNTISLRLWEAKARAEDLDLFQFNEGEYELAAQLH 274 +W+ G+ V A+AYD P+PG+ T N +LRLW+A+ E DL +FN G+Y+ + Sbjct: 247 SASQWIGGERVLAVAYDFPVPGFKTSNVNNLRLWQARPTTE-FDLNKFNNGDYKNSVAQQ 305 Query: 275 SRAQQICTVLYPGDATENGKLLRLKQQFFLCSASLQDIISRFHERSTTEGSRKWSEFPSK 334 RA+ I VLYP D GK LRLKQQ+F C+ASL DI+ RF + R W+EFP + Sbjct: 306 QRAESITAVLYPNDNFAQGKELRLKQQYFWCAASLHDILRRF-----KKSKRPWTEFPDQ 360 Query: 335 VAVQMNDTHPTLAIPELMRLLMDDNGLGWDEAWDVTSKTVAYTNHTVLPEALEKWSQSLM 394 VA+Q+NDTHPTLAI EL R+L+D L W EAWD+ +KT AYTNHTV+ EALEKW + L Sbjct: 361 VAIQLNDTHPTLAIVELQRVLVDLEKLDWHEAWDIVTKTFAYTNHTVMQEALEKWPRRLF 420 Query: 395 WKLLPRHMEIIEEIDKRFVQTIRDTRVDLEDKISSLSILDNNPQKPVVRMANLCVVSSHT 454 LLPRH+EII +I+ F++ + D +S +SI++ N + +RMA L +V SH Sbjct: 421 GHLLPRHLEIIYDINWFFLEDVAKKFPKDVDLLSRISIIEENSPERQIRMAFLAIVGSHK 480 Query: 455 VNGVAQLHSDILKAELFADYVSIW-PNKFQNKTNGITPRRWLRFCSPELSDIITKWLK-- 511 VNGV +LHS+++K +F D++ + P+KF N TNGITPRRWL+ +P L+ +I++ L Sbjct: 481 VNGVVELHSELIKTTIFKDFIKFYGPSKFVNVTNGITPRRWLKQANPSLAKLISETLNDP 540 Query: 512 TDKWITDLDLLTGLRQFADNEELQSEWASAKTANKKRLAQYIERVT-GVSI------DPT 564 T++++ D+ LT L ++ +++E +W K NK RL I++ GV I D T Sbjct: 541 TEEYLLDMAKLTQLEKYVEDKEFLKKWNQVKLNNKIRLVDLIKKENDGVDIINREYLDDT 600 Query: 565 SLFDIQVKRIHEYKRQLMNILGVVYRFKKLKEM-----KPEERKKTVPRTVMI-GGKAFA 618 LFD+QVKRIHEYKRQ +N+ G++YR+ +K M EE + PR V I GGK+ Sbjct: 601 -LFDMQVKRIHEYKRQQLNVFGIIYRYLAMKNMLKNGASIEEVARKYPRKVSIFGGKSAP 659 Query: 619 TYTNAKRIVKLVNDVGDVVNSDPEVNEYLKVVFVPNYNVTVAEMLIPGSELSQHISTAGM 678 Y AK I+KL+N V D+VN+D + LKVVFV +YNV+ AE++IP S+LS+HISTAG Sbjct: 660 GYYMAKLIIKLINCVADIVNNDESIEHLLKVVFVADYNVSKAEIIIPASDLSEHISTAGT 719 Query: 679 EASGTSNMKFALNGCLIIGTLDGANVEIREEVGEENFFLFGATADQVPRLRKEREDGLFK 738 EASGTSNMKF +NG LIIGT+DGANVEI E+GE+N FLFG ++ V LR + Sbjct: 720 EASGTSNMKFVMNGGLIIGTVDGANVEITREIGEDNVFLFGNLSENVEELRYNHQYHPQD 779 Query: 739 PDPRFEEAKQFVKSGVFG---SYDYGPLLDSLEGNTGFGRGDYFLVGYDFPSYMDAQAKV 795 + +++SG F ++ PL+DS++ + GDY+LV DF SY+ V Sbjct: 780 LPSSLDSVLSYIESGQFSPENPNEFKPLVDSIKYH-----GDYYLVSDDFESYLATHELV 834 Query: 796 DEAYKD-RKGWLKMSILSTAGSGKFSSDRTIAQYAKEIWNIE 836 D+ + + R WLK S+LS A G FSSDR I +Y+ IWN+E Sbjct: 835 DQEFHNQRSEWLKKSVLSLANVGFFSSDRCIEEYSDTIWNVE 876 >5IKP-A nrPDB Length = 846 Score = 680 bits (1755), Expect = 0.0, Method: Compositional matrix adjust. Identities = 385/834 (46%), Positives = 523/834 (62%), Gaps = 27/834 (3%) Query: 14 EKISAKANPEADDATEIAGNIVYHAKYSPHFSPLK----FGPEQALYATAESLRDRLIQL 69 ++IS + D E+ + H HF+ +K P +A A ++RD L+ Sbjct: 15 KQISVRGLAGLGDVAEVRKSFNRHL----HFTLVKDRNVATPRDYFFALAHTVRDHLVGR 70 Query: 70 WNETYVHFNKVDPKQTYYLSMEYLQGRALTNAIGNLNLQGPYADALRTLGYELEEIAEQE 129 W T H+ + DPK+ YYLS+E+ GR L N + NL LQ +A+ LG +LEE+ E E Sbjct: 71 WIRTQQHYYERDPKRIYYLSLEFYMGRTLQNTMVNLGLQNACDEAIYQLGLDLEELEEIE 130 Query: 130 KDAALGNGGLGRLASCFLDSMATLNLPAWGYGLRYRHGLFKQIITKKGQEEIPEDWLEKF 189 +DA LGNGGLGRLA+CFLDSMATL L A+GYG+RY G+F Q I Q E +DWL Sbjct: 131 EDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEADDWLRYG 190 Query: 190 SPWEIVRHDVVFPVRFFGKVQVNPDGSRKWVDGDVVQALAYDVPIPGYGTKNTISLRLWE 249 +PWE R + + PV F+G+V+ PDG KW+D VV A+ YD P+PGY ++RLW Sbjct: 191 NPWEKARPEYMLPVHFYGRVEHTPDGV-KWLDTQVVLAMPYDTPVPGYKNNTVNTMRLWS 249 Query: 250 AKARAEDLDLFQFNEGEYELAAQLHSRAQQICTVLYPGDATENGKLLRLKQQFFLCSASL 309 AKA D L FN G+Y A + A+ I VLYP D GK LRLKQ++F+ +A+L Sbjct: 250 AKA-PNDFKLQDFNVGDYIEAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATL 308 Query: 310 QDIISRFHERSTTEGSRK-----WSEFPSKVAVQMNDTHPTLAIPELMRLLMDDNGLGWD 364 QDII RF +S+ G R + FP KVA+Q+NDTHP L+IPELMR+L+D + WD Sbjct: 309 QDIIRRF--KSSKFGCRDPVRTCFETFPDKVAIQLNDTHPALSIPELMRILVDVEKVDWD 366 Query: 365 EAWDVTSKTVAYTNHTVLPEALEKWSQSLMWKLLPRHMEIIEEIDKRFVQTIRDTRVDLE 424 +AW++T KT AYTNHTVLPEALE+W S+ KLLPRH+EII I++R + + Sbjct: 367 KAWEITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALFPGDV 426 Query: 425 DKISSLSILDNNPQKPVVRMANLCVVSSHTVNGVAQLHSDILKAELFADYVSIWPNKFQN 484 D++ +S+++ K + MA+LCV+ SH VNGVA++HS+I+K +F D+ + P KFQN Sbjct: 427 DRLRRMSVIEEGDCKR-INMAHLCVIGSHAVNGVARIHSEIVKQSVFKDFYELEPEKFQN 485 Query: 485 KTNGITPRRWLRFCSPELSDIITKWLKTDKWITDLDLLTGLRQFADNEELQSEWASAKTA 544 KTNGITPRRWL C+P L+D I + + ++++TDL L L +E + A K Sbjct: 486 KTNGITPRRWLLLCNPGLADTIVEKI-GEEFLTDLSQLKKLLPLVSDEVFIRDVAKVKQE 544 Query: 545 NKKRLAQYIERVTGVSIDPTSLFDIQVKRIHEYKRQLMNILGVVYRFKKLKEMKPEERKK 604 NK + + ++E+ V I+P+S+FD+ VKRIHEYKRQL+N L VV + ++K + K Sbjct: 545 NKLKFSAFLEKEYKVKINPSSMFDVHVKRIHEYKRQLLNCLHVVTLYNRIKR---DPAKA 601 Query: 605 TVPRTVMIGGKAFATYTNAKRIVKLVNDVGDVVNSDPEVNEYLKVVFVPNYNVTVAEMLI 664 VPRTVMIGGKA Y AK I+KLV +GDVVN DP V + LKV+F+ NY V++AE +I Sbjct: 602 FVPRTVMIGGKAAPGYHMAKLIIKLVTSIGDVVNHDPVVGDRLKVIFLENYRVSLAEKVI 661 Query: 665 PGSELSQHISTAGMEASGTSNMKFALNGCLIIGTLDGANVEIREEVGEENFFLFGATADQ 724 P ++LSQ ISTAG EASGT NMKF LNG L IGT+DGANVE+ EE G EN F+FG + Sbjct: 662 PAADLSQQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGAENLFIFGLRVED 721 Query: 725 VPRLRKEREDG--LFKPDPRFEEAKQFVKSGVFGSYDYGPLLDSLEGNTGFGRGDYFLVG 782 V L ++ + + P ++A + SG F + D + D F V Sbjct: 722 VEALDRKGYNAREYYDHLPELKQAVDQISSGFFSPKEPDCFKDIV---NMLMHHDRFKVF 778 Query: 783 YDFPSYMDAQAKVDEAYKDRKGWLKMSILSTAGSGKFSSDRTIAQYAKEIWNIE 836 D+ +YM QA+VD+ Y++ K W K I + A SGKFSSDRTI +YA+EIW +E Sbjct: 779 ADYEAYMQCQAQVDQLYRNPKEWTKKVIRNIACSGKFSSDRTITEYAREIWGVE 832 >2ZB2-A nrPDB Length = 849 Score = 670 bits (1729), Expect = 0.0, Method: Compositional matrix adjust. Identities = 372/786 (47%), Positives = 505/786 (64%), Gaps = 15/786 (1%) Query: 56 YATAESLRDRLIQLWNETYVHFNKVDPKQTYYLSMEYLQGRALTNAIGNLNLQGPYADAL 115 +A A ++RD L+ W T H+ PK+ YYLS+E+ GR L N + NL LQ +A+ Sbjct: 56 FALAHTVRDHLVGRWIRTQQHYYDKCPKRVYYLSLEFYMGRTLQNTMINLGLQNACDEAI 115 Query: 116 RTLGYELEEIAEQEKDAALGNGGLGRLASCFLDSMATLNLPAWGYGLRYRHGLFKQIITK 175 LG ++EE+ E E+DA LGNGGLGRLA+CFLDSMATL L A+GYG+RY +G+F Q I Sbjct: 116 YQLGLDIEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFNQKIRD 175 Query: 176 KGQEEIPEDWLEKFSPWEIVRHDVVFPVRFFGKVQVNPDGSRKWVDGDVVQALAYDVPIP 235 Q E +DWL +PWE R + + PV F+GKV+ G+ KW+D VV AL YD P+P Sbjct: 176 GWQVEEADDWLRYGNPWEKSRPEFMLPVHFYGKVEHTNTGT-KWIDTQVVLALPYDTPVP 234 Query: 236 GYGTKNTISLRLWEAKARAEDLDLFQFNEGEYELAAQLHSRAQQICTVLYPGDATENGKL 295 GY ++RLW A+A D +L FN G+Y A + A+ I VLYP D GK Sbjct: 235 GYMNNTVNTMRLWSARA-PNDFNLRDFNVGDYIQAVLDRNLAENISRVLYPNDNFFEGKE 293 Query: 296 LRLKQQFFLCSASLQDIISRFHER---STTEGSRKWSEFPSKVAVQMNDTHPTLAIPELM 352 LRLKQ++F+ +A+LQDII RF ST + FP +VA+Q+NDTHP LAIPELM Sbjct: 294 LRLKQEYFVVAATLQDIIRRFKASKFGSTRGAGTVFDAFPDQVAIQLNDTHPALAIPELM 353 Query: 353 RLLMDDNGLGWDEAWDVTSKTVAYTNHTVLPEALEKWSQSLMWKLLPRHMEIIEEIDKRF 412 R+ +D L W +AW++T KT AYTNHTVLPEALE+W L+ KLLPRH+EII EI+++ Sbjct: 354 RIFVDIEKLPWSKAWELTQKTFAYTNHTVLPEALERWPVDLVEKLLPRHLEIIYEINQKH 413 Query: 413 VQTIRDTRVDLEDKISSLSILDNNPQKPVVRMANLCVVSSHTVNGVAQLHSDILKAELFA 472 + I D++ +S+++ K + MA+LC+V SH VNGVA++HSDI+K ++F Sbjct: 414 LDRIVALFPKDVDRLRRMSLIEEEGSKR-INMAHLCIVGSHAVNGVAKIHSDIVKTKVFK 472 Query: 473 DYVSIWPNKFQNKTNGITPRRWLRFCSPELSDIITKWLKTDKWITDLDLLTGLRQFADNE 532 D+ + P+KFQNKTNGITPRRWL C+P L+++I + + D ++ DL LT L F ++ Sbjct: 473 DFSELEPDKFQNKTNGITPRRWLLLCNPGLAELIAEKIGED-YVKDLSQLTKLHSFLGDD 531 Query: 533 ELQSEWASAKTANKKRLAQYIERVTGVSIDPTSLFDIQVKRIHEYKRQLMNILGVVYRFK 592 E A K NK + +Q++E V I+P+S+FD+QVKRIHEYKRQL+N L V+ + Sbjct: 532 VFLRELAKVKQENKLKFSQFLETEYKVKINPSSMFDVQVKRIHEYKRQLLNCLHVITMYN 591 Query: 593 KLKEMKPEERKKTVPRTVMIGGKAFATYTNAKRIVKLVNDVGDVVNSDPEVNEYLKVVFV 652 ++K+ + +K VPRTV+IGGKA Y AK I+KL+ V DVVN+DP V LKV+F+ Sbjct: 592 RIKK---DPKKLFVPRTVIIGGKAAPGYHMAKMIIKLITSVADVVNNDPMVGSKLKVIFL 648 Query: 653 PNYNVTVAEMLIPGSELSQHISTAGMEASGTSNMKFALNGCLIIGTLDGANVEIREEVGE 712 NY V++AE +IP ++LS+ ISTAG EASGT NMKF LNG L IGT+DGANVE+ EE GE Sbjct: 649 ENYRVSLAEKVIPATDLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGE 708 Query: 713 ENFFLFGATADQVPRLRKEREDG--LFKPDPRFEEAKQFVKSGVFGSYDYGPLLDSLEGN 770 EN F+FG D V L K+ + ++ P + + +G F D + N Sbjct: 709 ENLFIFGMRIDDVAALDKKGYEAKEYYEALPELKLVIDQIDNGFFSPKQPDLFKDII--N 766 Query: 771 TGFGRGDYFLVGYDFPSYMDAQAKVDEAYKDRKGWLKMSILSTAGSGKFSSDRTIAQYAK 830 F D F V D+ +Y+ Q KV + Y + K W M + + A SGKFSSDRTI +YA+ Sbjct: 767 MLFYH-DRFKVFADYEAYVKCQDKVSQLYMNPKAWNTMVLKNIAASGKFSSDRTIKEYAQ 825 Query: 831 EIWNIE 836 IWN+E Sbjct: 826 NIWNVE 831 >1AHP-A nrPDB Length = 797 Score = 624 bits (1609), Expect = e-179, Method: Compositional matrix adjust. Identities = 333/753 (44%), Positives = 466/753 (61%), Gaps = 21/753 (2%) Query: 83 KQTYYLSMEYLQGRALTNAIGNLNLQGPYADALRTLGYELEEIAEQEKDAALGNGGLGRL 142 + Y+SME+L GR N + NL D+L+ L ++ E+E D ALG GGLGRL Sbjct: 60 RHVNYISMEFLIGRLTGNNLLNLGWYQDVQDSLKAYDINLTDLLEEEIDPALGAGGLGRL 119 Query: 143 ASCFLDSMATLNLPAWGYGLRYRHGLFKQIITKKGQEEIPEDWLEKFSPWEIVRHDVVFP 202 A+CFLDSMAT+ A GYGL Y++GLF+Q Q E P+DW PW RH+ Sbjct: 120 AACFLDSMATVGQSATGYGLNYQYGLFRQSFVDGKQVEAPDDWHRSNYPW--FRHNEALD 177 Query: 203 VRFFGKVQVNPDGSRKWVDGDVVQALAYDVPIPGYGTKNTISLRLWEAKARAEDLDLFQF 262 V+ V DG +W + A+D+P+ GY LRLW+A A DL +F Sbjct: 178 VQVGIGGAVTKDG--RWEPEFTITGQAWDLPVVGYRNGVAQPLRLWQA-THAHPFDLTKF 234 Query: 263 NEGEYELAAQLHSRAQQICTVLYPGDATENGKLLRLKQQFFLCSASLQDIISRFHERSTT 322 N+G++ A Q A+++ VLYP D GK LRL QQ+F C+ S+ DI+ R H Sbjct: 235 NDGDFLRAEQQGINAEKLTKVLYPNDNHTAGKKLRLMQQYFQCACSVADILRRHHL---- 290 Query: 323 EGSRKWSEFPSKVAVQMNDTHPTLAIPELMRLLMDDNGLGWDEAWDVTSKTVAYTNHTVL 382 R+ E +Q+NDTHPT+AIPEL+R+L+D++ + WD+AW +TSKT AYTNHT++ Sbjct: 291 -AGRELHELADYEVIQLNDTHPTIAIPELLRVLIDEHQMSWDDAWAITSKTFAYTNHTLM 349 Query: 383 PEALEKWSQSLMWKLLPRHMEIIEEIDKRFVQTIRDTRVDLEDKISSLSILDNNPQKPVV 442 PEALE+W L+ LLPRHM+II EI+ RF + T E + L+++ + V Sbjct: 350 PEALERWDVKLVKGLLPRHMQIINEINTRFKTLVEKTWPGDEKVWAKLAVVHDKQ----V 405 Query: 443 RMANLCVVSSHTVNGVAQLHSDILKAELFADYVSIWPNKFQNKTNGITPRRWLRFCSPEL 502 MANLCVV VNGVA LHSD++ +LF +Y +WPNKF N TNGITPRRW++ C+P L Sbjct: 406 HMANLCVVGGFAVNGVAALHSDLVVKDLFPEYHQLWPNKFHNVTNGITPRRWIKQCNPAL 465 Query: 503 SDIITKWLKTDKWITDLDLLTGLRQFADNEELQSEWASAKTANKKRLAQYIERVTGVSID 562 + ++ K L+ + W DLD L L + AD+ + + + K ANK RLA++++ TG+ I+ Sbjct: 466 AALLDKSLQKE-WANDLDQLINLVKLADDAKFRDLYRVIKQANKVRLAEFVKVRTGIDIN 524 Query: 563 PTSLFDIQVKRIHEYKRQLMNILGVVYRFKKLKEMKPEERKKTVPRTVMIGGKAFATYTN 622 P ++FDIQ+KR+HEYKRQ +N+L ++ +K+++E +R VPR + G KA Y Sbjct: 525 PQAIFDIQIKRLHEYKRQHLNLLRILALYKEIRENPQADR---VPRVFLFGAKAAPGYYL 581 Query: 623 AKRIVKLVNDVGDVVNSDPEVNEYLKVVFVPNYNVTVAEMLIPGSELSQHISTAGMEASG 682 AK I+ +N V DV+N+DP V + LKVVF+P+Y V+ AE LIP +++S+ ISTAG EASG Sbjct: 582 AKNIIFAINKVADVINNDPLVGDKLKVVFLPDYCVSAAEKLIPAADISEQISTAGKEASG 641 Query: 683 TSNMKFALNGCLIIGTLDGANVEIREEVGEENFFLFGATADQVPRLRKEREDGL--FKPD 740 T NMK ALNG L +GTLDGANVEI E+VGEEN F+FG T QV + + D + K D Sbjct: 642 TGNMKLALNGALTVGTLDGANVEIAEKVGEENIFIFGHTVKQVKAILAKGYDPVKWRKKD 701 Query: 741 PRFEEAKQFVKSGVFGSYDYGPLLDSLEGNTGFGRGDYFLVGYDFPSYMDAQAKVDEAYK 800 + + ++SG + D D + + G GD +LV DF +Y++AQ +VD Y+ Sbjct: 702 KVLDAVLKELESGKYSDGDKHA-FDQMLHSIGKQGGDPYLVMADFAAYVEAQKQVDVLYR 760 Query: 801 DRKGWLKMSILSTAGSGKFSSDRTIAQYAKEIW 833 D++ W + +IL+TA G FSSDR+I Y IW Sbjct: 761 DQEAWTRAAILNTARCGMFSSDRSIRDYQARIW 793 >2C4M-A nrPDB Length = 796 Score = 620 bits (1599), Expect = e-178, Method: Compositional matrix adjust. Identities = 350/788 (44%), Positives = 482/788 (61%), Gaps = 38/788 (4%) Query: 59 AESLRDRLIQLWNETYVHFNKVDPKQTYYLSMEYLQGRALTNAIGNLNLQGPYADALRTL 118 + ++++R+ W T + +Q +Y S E+L GRAL N + NL L A A R L Sbjct: 38 SRAVQERIADDWERTREAYGAA--RQQHYFSAEFLMGRALLNNLTNLGLVDEAAAATREL 95 Query: 119 GYELEEIAEQEKDAALGNGGLGRLASCFLDSMATLNLPAWGYGLRYRHGLFKQIITKKGQ 178 G+EL +I E E DAALGNGGLGRLA+CFLDS T + P GYGL YR GLF+Q + Q Sbjct: 96 GHELTDILEIENDAALGNGGLGRLAACFLDSAVTQDYPVTGYGLLYRFGLFRQSFNEGFQ 155 Query: 179 EEIPEDWLEKFSPWEIVRHDVVFPVRFFGKVQVNPDGSRKWVDGDVVQALAYDVPIPGYG 238 E P+ W E+ P+ I R V F D +A+ YD+PI GYG Sbjct: 156 VEKPDPWREEEYPFTIRRASDQLVVCF---------------DDMKTRAIPYDMPITGYG 200 Query: 239 TKNTISLRLWEAKARAEDLDLFQFNEGEYELAAQLHSRAQQICTVLYPGDATENGKLLRL 298 T N +LRLW+A+ E+ D FN + A R IC VLYP D T GK LR+ Sbjct: 201 THNVGTLRLWKAEP-WEEFDYDAFNAQRFTDAIIERERVSDICRVLYPNDTTYEGKKLRV 259 Query: 299 KQQFFLCSASLQDIISRFHERSTTEGSRKWSEFPSKVAVQMNDTHPTLAIPELMRLLMDD 358 +QQ+F SASLQ +I + + S F +VQ+NDTHP LAIPELMRLLMD+ Sbjct: 260 RQQYFFTSASLQAMI-----QDHLAHHKDLSNFAEFHSVQLNDTHPVLAIPELMRLLMDE 314 Query: 359 NGLGWDEAWDVTSKTVAYTNHTVLPEALEKWSQSLMWKLLPRHMEIIEEIDKRFVQTIRD 418 + +GW+E+W + SKT AYTNHTVL EALE+W + + +L R EII EID+RF Sbjct: 315 HDMGWEESWAIVSKTFAYTNHTVLTEALEQWDEQIFQQLFWRVWEIIAEIDRRFRLERAA 374 Query: 419 TRVDLEDKISSLSILDNNPQKPVVRMANLCVVSSHTVNGVAQLHSDILKAELFADYVSIW 478 +D E+ I+ ++ + Q V MA + +++++NGVA LH++I+KAE AD+ ++W Sbjct: 375 DGLD-EETINRMAPI----QHGTVHMAWIACYAAYSINGVAALHTEIIKAETLADWYALW 429 Query: 479 PNKFQNKTNGITPRRWLRFCSPELSDIITKWLKTDKWITDLDLLTGLRQFADNEELQSEW 538 P KF NKTNG+TPRRWLR +P LSD++T+ +D W+TDLD L LR +AD++ + E Sbjct: 430 PEKFNNKTNGVTPRRWLRMINPGLSDLLTRLSGSDDWVTDLDELKKLRSYADDKSVLEEL 489 Query: 539 ASAKTANKKRLAQYIERVTGVSIDPTSLFDIQVKRIHEYKRQLMNILGVVYRFKKLKEMK 598 + K ANK+ A++I G+ IDP S+FD+Q+KR+HEYKRQLMN L V+ + ++K Sbjct: 490 RAIKAANKQDFAEWILERQGIEIDPESIFDVQIKRLHEYKRQLMNALYVLDLYFRIK--- 546 Query: 599 PEERKKTVP-RTVMIGGKAFATYTNAKRIVKLVNDVGDVVNSDPEVNEYLKVVFVPNYNV 657 E+ +P RTV+ G KA Y AK I+KL+N + D+VN+DPEV+ LKVVFV NYNV Sbjct: 547 -EDGLTDIPARTVIFGAKAAPGYVRAKAIIKLINSIADLVNNDPEVSPLLKVVFVENYNV 605 Query: 658 TVAEMLIPGSELSQHISTAGMEASGTSNMKFALNGCLIIGTLDGANVEIREEVGEENFFL 717 + AE ++P S++S+ ISTAG EASGTSNMKF +NG L +GT+DGANVEI + VGEEN ++ Sbjct: 606 SPAEHILPASDVSEQISTAGKEASGTSNMKFMMNGALTLGTMDGANVEIVDSVGEENAYI 665 Query: 718 FGATADQVPRLRKE-REDGLFKPDPRFEEAKQFVKSGVFGSYDYGPLLD---SLEGNTGF 773 FGA +++P LR+ + L++ P + A + +G + G D SL G Sbjct: 666 FGARVEELPALRESYKPYELYETVPGLKRALDALDNGTLNDNNSGLFYDLKHSLIHGYGK 725 Query: 774 GRGDYFLVGYDFPSYMDAQAKVDEAY-KDRKGWLKMSILSTAGSGKFSSDRTIAQYAKEI 832 D + V DF Y + + ++ Y D GW +M+ ++ SG+FSSDRTI YA EI Sbjct: 726 DASDTYYVLGDFADYRETRDRMAADYASDPLGWARMAWINICESGRFSSDRTIRDYATEI 785 Query: 833 WNIEACPV 840 W +E P Sbjct: 786 WKLEPTPA 793 >5LR8-A nrPDB Length = 938 Score = 577 bits (1486), Expect = e-165, Method: Compositional matrix adjust. Identities = 267/408 (65%), Positives = 333/408 (81%), Gaps = 2/408 (0%) Query: 436 NPQKP-VVRMANLCVVSSHTVNGVAQLHSDILKAELFADYVSIWPNKFQNKTNGITPRRW 494 +PQ P VVRMANLCVV H+VNGVA++HS+I+K ++F + +WP KFQNKTNG+TPRRW Sbjct: 519 DPQFPRVVRMANLCVVGGHSVNGVAEIHSEIVKQDVFNSFYEMWPTKFQNKTNGVTPRRW 578 Query: 495 LRFCSPELSDIITKWLKTDKWITDLDLLTGLRQFADNEELQSEWASAKTANKKRLAQYIE 554 +RFC+PELS II+KW+ +D WI + D L GL++FAD+E+LQSEW +AK NK ++ I Sbjct: 579 IRFCNPELSTIISKWIGSDDWILNTDKLAGLKKFADDEDLQSEWRTAKRNNKMKVVSLIR 638 Query: 555 RVTGVSIDPTSLFDIQVKRIHEYKRQLMNILGVVYRFKKLKEMKPEERKKT-VPRTVMIG 613 TG + P ++FD+QVKRIHEYKRQL+NILG+VYR+KK+KEM ++R+K+ VPR + G Sbjct: 639 DKTGYIVSPDAMFDVQVKRIHEYKRQLLNILGIVYRYKKMKEMSAKDRRKSFVPRVCIFG 698 Query: 614 GKAFATYTNAKRIVKLVNDVGDVVNSDPEVNEYLKVVFVPNYNVTVAEMLIPGSELSQHI 673 GKAFATY AKRIVK + DV VN DP++ + LKVVFVP+YNV+VAE LIP SELSQHI Sbjct: 699 GKAFATYVQAKRIVKFITDVAATVNYDPDIGDLLKVVFVPDYNVSVAETLIPASELSQHI 758 Query: 674 STAGMEASGTSNMKFALNGCLIIGTLDGANVEIREEVGEENFFLFGATADQVPRLRKERE 733 STAGMEASGTSNMKFA+NGCL+IGTLDGANVEIREEVGEENFFLFGA A ++ LR+ER Sbjct: 759 STAGMEASGTSNMKFAMNGCLLIGTLDGANVEIREEVGEENFFLFGAHAPEIAGLRQERA 818 Query: 734 DGLFKPDPRFEEAKQFVKSGVFGSYDYGPLLDSLEGNTGFGRGDYFLVGYDFPSYMDAQA 793 +G F PD RFEE K++V+SGVFG+ +Y L+ SLEGN G+GR DYFLVG DFPSY++ Q Sbjct: 819 EGKFVPDLRFEEVKEYVRSGVFGTSNYDELMGSLEGNEGYGRADYFLVGKDFPSYIECQE 878 Query: 794 KVDEAYKDRKGWLKMSILSTAGSGKFSSDRTIAQYAKEIWNIEACPVP 841 KVDEAY+D+K W +MSIL+TAGS KFSSDRTI +YAK+IW+I +P Sbjct: 879 KVDEAYRDQKLWTRMSILNTAGSPKFSSDRTIHEYAKDIWDISPVIMP 926 Score = 531 bits (1367), Expect = e-151, Method: Compositional matrix adjust. Identities = 255/416 (61%), Positives = 315/416 (75%), Gaps = 9/416 (2%) Query: 26 DATEIAGNIVYHAKYSPHFSPLKFGPEQALYATAESLRDRLIQLWNETYVHFNKVDPKQT 85 D++ IA NI +HA ++P FSP P +A +ATA+S+ D LI WN TY ++NKV+ KQ Sbjct: 28 DSSAIASNIQHHADFTPLFSPEHSSPLKAYHATAKSVFDSLIMNWNATYDYYNKVNAKQA 87 Query: 86 YYLSMEYLQGRALTNAIGNLNLQGPYADALRTLGYELEEIAEQEKDAALGNGGLGRLASC 145 YYLSME+LQGRALTNAIGNL L G YA+AL+ LG+ LE++A QE D ALGNGGLGRLASC Sbjct: 88 YYLSMEFLQGRALTNAIGNLELTGQYAEALKQLGHNLEDVASQEPDPALGNGGLGRLASC 147 Query: 146 FLDSMATLNLPAWGYGLRYRHGLFKQIITKKGQEEIPEDWLEKFSPWEIVRHDVVFPVRF 205 FLDS+ATLN PAWGYGLRYR+GLFKQIITK GQEE+ E+WLE +PWEIVR+DV +PV+F Sbjct: 148 FLDSLATLNYPAWGYGLRYRYGLFKQIITKDGQEEVAENWLEMGNPWEIVRNDVSYPVKF 207 Query: 206 FGKVQVNPDGSRKWVDGDVVQALAYDVPIPGYGTKNTISLRLWEAKARAEDLDLFQFNEG 265 +GKV DG + W+ G+ ++A+A+DVPIPGY TK T +LRLW +++ DL FN G Sbjct: 208 YGKVVEGTDGRKHWIGGENIKAVAHDVPIPGYKTKTTNNLRLWSTTVPSQNFDLGAFNAG 267 Query: 266 EYELAAQLHSRAQQICTVLYPGDATENGKLLRLKQQFFLCSASLQDIISRFHERSTTEGS 325 ++ A + H A++IC VLYPGD + GK+LRLKQQ+ LCSASLQDIISRF R+ S Sbjct: 268 DHAKANEAHLNAEKICHVLYPGDESSEGKILRLKQQYTLCSASLQDIISRFESRAGD--S 325 Query: 326 RKWSEFPSKVAVQMNDTHPTLAIPELMRLLMDDNGLGWDEAWDVTSKTVAYTNHTVLPEA 385 W +FPSKVAVQMNDTHPTL IPELMR+LMD GL W+EAW +T +TVAYTNHTVLPEA Sbjct: 326 LNWEDFPSKVAVQMNDTHPTLCIPELMRILMDIKGLSWNEAWSITERTVAYTNHTVLPEA 385 Query: 386 LEKWSQSLMWKLLPRHMEIIEEIDKRFVQTI------RDTRVDLEDKISSLSILDN 435 LEKWS +M KLLPRH+EIIE ID+ + I D + L+ K+ + ILDN Sbjct: 386 LEKWSLDIMQKLLPRHVEIIETIDEELMNNIVSKYGTADISL-LKQKLKDMRILDN 440 >4L22-A nrPDB Length = 758 Score = 460 bits (1184), Expect = e-129, Method: Compositional matrix adjust. Identities = 281/762 (36%), Positives = 415/762 (54%), Gaps = 65/762 (8%) Query: 83 KQTYYLSMEYLQGRALTNAIGNLNLQGPYADALRTLGYELEEIAEQEKDAALGNGGLGRL 142 ++ YY+S E+L G+ L+N + NL L D L G + ++ + E + +LGNGGLGRL Sbjct: 50 RKVYYISAEFLIGKLLSNNLINLGLYKTVKDELAAAGKSISQVEDVELEPSLGNGGLGRL 109 Query: 143 ASCFLDSMATLNLPAWGYGLRYRHGLFKQIITKKGQEEIPEDWLEKFSPWEIVRHDVVFP 202 ASCF+DSMATL + G GL Y GLFKQ+ QE P W+E S Sbjct: 110 ASCFIDSMATLGINGEGVGLNYHCGLFKQVFRDNQQEAEPNYWIEDDS------------ 157 Query: 203 VRFFGKVQVNPDGSRKWVDGDVVQALAYDVPIPGYGTKNTISLR--LWEAKARAEDLDLF 260 W+ V A++YDVP + K+ + L K L+LF Sbjct: 158 ----------------WL---VPTAISYDVPFRDFTLKSKLDRIDILGYHKDSKNYLNLF 198 Query: 261 QFNEGEYELAAQ-----LHSRAQQICTVLYPGDATENGKLLRLKQQFFLCSASLQDIISR 315 + +Y L + + LYP D+ +NG+LLR+ QQ+F+ S + Q +I Sbjct: 199 DIDGLDYGLIKDGITFDKTEIKKNLTLFLYPDDSDKNGELLRIYQQYFMVSNAAQLLIDE 258 Query: 316 FHERSTTEGSRKWSEFPSKVAVQMNDTHPTLAIPELMRLLMDDNGLGWDEAWDVTSKTVA 375 ER + + VQ+NDTHP++ IPEL+RLL + +GL + EA D+ + Sbjct: 259 ALERGSN-----LHDLADYAYVQINDTHPSMVIPELIRLLNEKHGLDFYEAVDIVKNMIG 313 Query: 376 YTNHTVLPEALEKWSQSLMWKLLPRHMEIIEEIDKRFVQTIRDTRVDLEDKISSLSILDN 435 YTNHT+L EALEKW + +++P + IIE +D+ +D ++ I+D Sbjct: 314 YTNHTILAEALEKWPLEYLNEVVPHLVTIIEHLDRIVRSQYKD---------DAVQIIDR 364 Query: 436 NPQKPVVRMANLCVVSSHTVNGVAQLHSDILKAELFADYVSIWPNKFQNKTNGITPRRWL 495 + + V MA++ + S +VNGVA LH+DILK + I+P KF NKTNGIT RRWL Sbjct: 365 DDR---VHMAHMDIHFSTSVNGVAALHTDILKNSELKPFYDIYPEKFNNKTNGITFRRWL 421 Query: 496 RFCSPELSDIITKWLKTDKWITDLDLLTGLRQFADNEELQSEWASAKTANKKRLAQYIER 555 F + +L+ I K L + ++ D L L FAD++ + + A K NK L +Y++ Sbjct: 422 EFANQDLAAYI-KELIGEGYLEDATELEKLLAFADDKTVHEQLAKIKFNNKLALKRYLKE 480 Query: 556 VTGVSIDPTSLFDIQVKRIHEYKRQLMNILGVVYRFKKLKEMKPEERKKTVPRTVMIGGK 615 G+++D S+ D Q+KR HEYKRQ MN L V+Y++ ++K+ +RK TV+ GGK Sbjct: 481 NKGINLDENSIIDTQIKRFHEYKRQQMNALYVIYKYLEIKKGNLPKRK----ITVIFGGK 536 Query: 616 AFATYTNAKRIVKLVNDVGDVVNSDPEVNEYLKVVFVPNYNVTVAEMLIPGSELSQHIST 675 A YT A+ I+ L+ + +++N+DP+V+ YL V V NYNVTVAE LIP +++S+ IS Sbjct: 537 AAPAYTIAQDIIHLILCLSELINNDPDVSPYLNVFLVENYNVTVAEKLIPATDISEQISL 596 Query: 676 AGMEASGTSNMKFALNGCLIIGTLDGANVEIREEVGEENFFLFGATADQVPRLRKE---R 732 A EASGT NMKF LNG L +GT+DGANVEI E VG +N ++FG +D + L + Sbjct: 597 ASKEASGTGNMKFMLNGALTLGTMDGANVEIAELVGSDNIYIFGKDSDTIIDLYDKGTYV 656 Query: 733 EDGLFKPDPRFEEAKQFVKSGVFGSYDYGPLLDSLEGNTGFGRGDYFLVGYDFPSYMDAQ 792 + + +EA F+ S + L+ L D+F+ D Y+ + Sbjct: 657 SKDYYTNNAVIKEAVDFIVSKDVLALGKKERLERLYHE--LINKDWFMTLIDLKEYIAKK 714 Query: 793 AKVDEAYKDRKGWLKMSILSTAGSGKFSSDRTIAQYAKEIWN 834 ++ Y+D+ W K I + A +G FSSDRTI QY K+IW+ Sbjct: 715 EEMLADYEDQNVWNKKVIQNIAKAGFFSSDRTIQQYDKDIWH 756 >2O57-A nrPDB Length = 297 Score = 32.7 bits (73), Expect = 0.67, Method: Compositional matrix adjust. Identities = 25/93 (26%), Positives = 45/93 (48%), Gaps = 9/93 (9%) Query: 510 LKTDKWITDLDLLTG-LRQFADNEELQSEWASAKTANKKRLAQYIERVTGVSIDPTSLFD 568 L+TD+W+ +TG L++ A +L + + A A+++ R GVSID ++ Sbjct: 64 LRTDEWLASELAMTGVLQRQAKGLDLGAGYGGA--------ARFLVRKFGVSIDCLNIAP 115 Query: 569 IQVKRIHEYKRQLMNILGVVYRFKKLKEMKPEE 601 +Q KR EY Q + ++ E+ E+ Sbjct: 116 VQNKRNEEYNNQAGLADNITVKYGSFLEIPCED 148 >4UOQ-A nrPDB Length = 695 Score = 31.2 bits (69), Expect = 2.2, Method: Compositional matrix adjust. Identities = 28/94 (29%), Positives = 45/94 (47%), Gaps = 9/94 (9%) Query: 532 EELQSEWASAKTAN-KKRLAQYIERVTGVSIDPTSLFDIQVKRIH-EYKRQLMNILGVVY 589 +++QSEWA+ TA + + ++ E + + V IH ++ ++ VY Sbjct: 421 QDIQSEWATEHTATPTQHIREWTEPLDWFAAFANRGVTADVTPIHAQWDTYDAVVIPCVY 480 Query: 590 RFKKLKEMKPEERKKTVPRTVMIGGKAFATYTNA 623 F + EM ER +T R GGKAF TY +A Sbjct: 481 LFSE--EMA--ERLRTFVRN---GGKAFVTYYSA 507 >4KS7-A nrPDB Length = 292 Score = 30.8 bits (68), Expect = 2.6, Method: Compositional matrix adjust. Identities = 18/50 (36%), Positives = 27/50 (54%), Gaps = 11/50 (22%) Query: 69 LWNET-----YVHFNKVDPKQTYYLS------MEYLQGRALTNAIGNLNL 107 L+NE Y HFN V+ ++Y + ME+LQG ALT+ + + L Sbjct: 67 LFNEVVIMRDYQHFNVVEMYKSYLVGEELWVLMEFLQGGALTDIVSQVRL 116 >5I2T-A nrPDB Length = 742 Score = 30.8 bits (68), Expect = 2.6, Method: Compositional matrix adjust. Identities = 13/40 (32%), Positives = 22/40 (55%), Gaps = 3/40 (7%) Query: 31 AGNIVYHAKYSPHFSPLKFGPEQALYATAESLRDRLIQLW 70 A N+++H + S +KF P+ L+A A R +Q+W Sbjct: 111 ARNVLHHFNFKEKCSAVKFSPDGRLFALASG---RFLQIW 147 >5WLC-LO nrPDB Length = 923 Score = 30.8 bits (68), Expect = 2.7, Method: Compositional matrix adjust. Identities = 13/40 (32%), Positives = 22/40 (55%), Gaps = 3/40 (7%) Query: 31 AGNIVYHAKYSPHFSPLKFGPEQALYATAESLRDRLIQLW 70 A N+++H + S +KF P+ L+A A R +Q+W Sbjct: 86 ARNVLHHFNFKEKCSAVKFSPDGRLFALASG---RFLQIW 122 >1KG4-A nrPDB Length = 225 Score = 30.4 bits (67), Expect = 3.3, Method: Compositional matrix adjust. Identities = 15/65 (23%), Positives = 34/65 (52%), Gaps = 1/65 (1%) Query: 220 VDGDVVQALAYDVPIPGYGTKNTISLRLWEAKARAED-LDLFQFNEGEYELAAQLHSRAQ 278 +DG+V + LA + G+ K + +LW + + + +FN+ +L A + +R++ Sbjct: 137 LDGNVARVLARCYAVSGWPGKKEVENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSK 196 Query: 279 QICTV 283 C++ Sbjct: 197 PKCSL 201 >1OFH-G nrPDB Length = 174 Score = 30.4 bits (67), Expect = 3.5, Method: Compositional matrix adjust. Identities = 15/44 (34%), Positives = 25/44 (56%), Gaps = 2/44 (4%) Query: 629 LVNDVGDVVNSDPEVNEYLKVVFVPNYNVTVAEMLIPGSELSQH 672 ++ +GDVV PE ++ L + NY ++ A L+ +ELS H Sbjct: 105 IITGIGDVVQ--PEEDQILAIGSGGNYALSAARALVENTELSAH 146 >1KA0-A nrPDB Length = 357 Score = 29.6 bits (65), Expect = 6.1, Method: Compositional matrix adjust. Identities = 21/68 (30%), Positives = 33/68 (48%), Gaps = 12/68 (17%) Query: 723 DQVPRLRKEREDGLFKPD----PRFEEAKQFVKSGVFGSYDYGP-----LLDSLEGNTGF 773 D+V +++D LF D E+ +Q + FG+Y+ G LD ++G GF Sbjct: 94 DEVYNKNYKKDDFLFTNDQFPLKSLEDVRQIID---FGNYEGGRKGRFWCLDPIDGTKGF 150 Query: 774 GRGDYFLV 781 RG+ F V Sbjct: 151 LRGEQFAV 158 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4BQE-A nrPDB 1333 0.0 5OX0-A nrPDB 1252 0.0 5IKP-A nrPDB 1250 0.0 2ZB2-A nrPDB 1225 0.0 1YGP-A nrPDB 1078 0.0 1AHP-A nrPDB 1069 0.0 2C4M-A nrPDB 1055 0.0 4L22-A nrPDB 916 0.0 5LR8-A nrPDB 630 0.0 Sequences not found previously or not previously below threshold: 4KMA-A nrPDB 34 0.29 3G33-B nrPDB 34 0.34 5IM3-A nrPDB 32 1.1 1TUE-B nrPDB 32 1.4 1J2Z-A nrPDB 32 1.7 5NCK-A nrPDB 31 2.7 5OQM-l nrPDB 30 3.0 3HR7-A nrPDB 30 4.3 6NCW-A nrPDB 30 6.0 4QHP-A nrPDB 29 7.3 6HIV-CJ nrPDB 29 7.9 2YA2-A nrPDB 29 8.5 CONVERGED! >4BQE-A nrPDB Length = 874 Score = 1333 bits (3449), Expect = 0.0, Method: Composition-based stats. Identities = 841/841 (100%), Positives = 841/841 (100%) Query: 1 MANANGKAATSLPEKISAKANPEADDATEIAGNIVYHAKYSPHFSPLKFGPEQALYATAE 60 MANANGKAATSLPEKISAKANPEADDATEIAGNIVYHAKYSPHFSPLKFGPEQALYATAE Sbjct: 34 MANANGKAATSLPEKISAKANPEADDATEIAGNIVYHAKYSPHFSPLKFGPEQALYATAE 93 Query: 61 SLRDRLIQLWNETYVHFNKVDPKQTYYLSMEYLQGRALTNAIGNLNLQGPYADALRTLGY 120 SLRDRLIQLWNETYVHFNKVDPKQTYYLSMEYLQGRALTNAIGNLNLQGPYADALRTLGY Sbjct: 94 SLRDRLIQLWNETYVHFNKVDPKQTYYLSMEYLQGRALTNAIGNLNLQGPYADALRTLGY 153 Query: 121 ELEEIAEQEKDAALGNGGLGRLASCFLDSMATLNLPAWGYGLRYRHGLFKQIITKKGQEE 180 ELEEIAEQEKDAALGNGGLGRLASCFLDSMATLNLPAWGYGLRYRHGLFKQIITKKGQEE Sbjct: 154 ELEEIAEQEKDAALGNGGLGRLASCFLDSMATLNLPAWGYGLRYRHGLFKQIITKKGQEE 213 Query: 181 IPEDWLEKFSPWEIVRHDVVFPVRFFGKVQVNPDGSRKWVDGDVVQALAYDVPIPGYGTK 240 IPEDWLEKFSPWEIVRHDVVFPVRFFGKVQVNPDGSRKWVDGDVVQALAYDVPIPGYGTK Sbjct: 214 IPEDWLEKFSPWEIVRHDVVFPVRFFGKVQVNPDGSRKWVDGDVVQALAYDVPIPGYGTK 273 Query: 241 NTISLRLWEAKARAEDLDLFQFNEGEYELAAQLHSRAQQICTVLYPGDATENGKLLRLKQ 300 NTISLRLWEAKARAEDLDLFQFNEGEYELAAQLHSRAQQICTVLYPGDATENGKLLRLKQ Sbjct: 274 NTISLRLWEAKARAEDLDLFQFNEGEYELAAQLHSRAQQICTVLYPGDATENGKLLRLKQ 333 Query: 301 QFFLCSASLQDIISRFHERSTTEGSRKWSEFPSKVAVQMNDTHPTLAIPELMRLLMDDNG 360 QFFLCSASLQDIISRFHERSTTEGSRKWSEFPSKVAVQMNDTHPTLAIPELMRLLMDDNG Sbjct: 334 QFFLCSASLQDIISRFHERSTTEGSRKWSEFPSKVAVQMNDTHPTLAIPELMRLLMDDNG 393 Query: 361 LGWDEAWDVTSKTVAYTNHTVLPEALEKWSQSLMWKLLPRHMEIIEEIDKRFVQTIRDTR 420 LGWDEAWDVTSKTVAYTNHTVLPEALEKWSQSLMWKLLPRHMEIIEEIDKRFVQTIRDTR Sbjct: 394 LGWDEAWDVTSKTVAYTNHTVLPEALEKWSQSLMWKLLPRHMEIIEEIDKRFVQTIRDTR 453 Query: 421 VDLEDKISSLSILDNNPQKPVVRMANLCVVSSHTVNGVAQLHSDILKAELFADYVSIWPN 480 VDLEDKISSLSILDNNPQKPVVRMANLCVVSSHTVNGVAQLHSDILKAELFADYVSIWPN Sbjct: 454 VDLEDKISSLSILDNNPQKPVVRMANLCVVSSHTVNGVAQLHSDILKAELFADYVSIWPN 513 Query: 481 KFQNKTNGITPRRWLRFCSPELSDIITKWLKTDKWITDLDLLTGLRQFADNEELQSEWAS 540 KFQNKTNGITPRRWLRFCSPELSDIITKWLKTDKWITDLDLLTGLRQFADNEELQSEWAS Sbjct: 514 KFQNKTNGITPRRWLRFCSPELSDIITKWLKTDKWITDLDLLTGLRQFADNEELQSEWAS 573 Query: 541 AKTANKKRLAQYIERVTGVSIDPTSLFDIQVKRIHEYKRQLMNILGVVYRFKKLKEMKPE 600 AKTANKKRLAQYIERVTGVSIDPTSLFDIQVKRIHEYKRQLMNILGVVYRFKKLKEMKPE Sbjct: 574 AKTANKKRLAQYIERVTGVSIDPTSLFDIQVKRIHEYKRQLMNILGVVYRFKKLKEMKPE 633 Query: 601 ERKKTVPRTVMIGGKAFATYTNAKRIVKLVNDVGDVVNSDPEVNEYLKVVFVPNYNVTVA 660 ERKKTVPRTVMIGGKAFATYTNAKRIVKLVNDVGDVVNSDPEVNEYLKVVFVPNYNVTVA Sbjct: 634 ERKKTVPRTVMIGGKAFATYTNAKRIVKLVNDVGDVVNSDPEVNEYLKVVFVPNYNVTVA 693 Query: 661 EMLIPGSELSQHISTAGMEASGTSNMKFALNGCLIIGTLDGANVEIREEVGEENFFLFGA 720 EMLIPGSELSQHISTAGMEASGTSNMKFALNGCLIIGTLDGANVEIREEVGEENFFLFGA Sbjct: 694 EMLIPGSELSQHISTAGMEASGTSNMKFALNGCLIIGTLDGANVEIREEVGEENFFLFGA 753 Query: 721 TADQVPRLRKEREDGLFKPDPRFEEAKQFVKSGVFGSYDYGPLLDSLEGNTGFGRGDYFL 780 TADQVPRLRKEREDGLFKPDPRFEEAKQFVKSGVFGSYDYGPLLDSLEGNTGFGRGDYFL Sbjct: 754 TADQVPRLRKEREDGLFKPDPRFEEAKQFVKSGVFGSYDYGPLLDSLEGNTGFGRGDYFL 813 Query: 781 VGYDFPSYMDAQAKVDEAYKDRKGWLKMSILSTAGSGKFSSDRTIAQYAKEIWNIEACPV 840 VGYDFPSYMDAQAKVDEAYKDRKGWLKMSILSTAGSGKFSSDRTIAQYAKEIWNIEACPV Sbjct: 814 VGYDFPSYMDAQAKVDEAYKDRKGWLKMSILSTAGSGKFSSDRTIAQYAKEIWNIEACPV 873 Query: 841 P 841 P Sbjct: 874 P 874 >5OX0-A nrPDB Length = 843 Score = 1252 bits (3240), Expect = 0.0, Method: Composition-based stats. Identities = 393/843 (46%), Positives = 528/843 (62%), Gaps = 31/843 (3%) Query: 14 EKISAKANPEADDATEIAGNIVYHAKYSPHFSPLK----FGPEQALYATAESLRDRLIQL 69 ++IS + ++ TE+ N H HF+ +K P +A A ++RD L+ Sbjct: 12 KQISVRGLAGVENVTELKKNFNRHL----HFTLVKDRNVATPRDYYFALAHTVRDHLVGR 67 Query: 70 WNETYVHFNKVDPKQTYYLSMEYLQGRALTNAIGNLNLQGPYADALRTLGYELEEIAEQE 129 W T H+ + DPK+ YYLS+E+ GR L N + NL L+ +A LG ++EE+ E E Sbjct: 68 WIRTQQHYYEKDPKRIYYLSLEFYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIE 127 Query: 130 KDAALGNGGLGRLASCFLDSMATLNLPAWGYGLRYRHGLFKQIITKKGQEEIPEDWLEKF 189 +DA LGNGGLGRLA+CFLDSMATL L A+GYG+RY G+F Q I Q E +DWL Sbjct: 128 EDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYG 187 Query: 190 SPWEIVRHDVVFPVRFFGKVQVNPDGSRKWVDGDVVQALAYDVPIPGYGTKNTISLRLWE 249 +PWE R + PV F+G+V+ G+ KWVD VV A+ YD P+PGY ++RLW Sbjct: 188 NPWEKARPEFTLPVHFYGRVEHTSQGA-KWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWS 246 Query: 250 AKARAEDLDLFQFNEGEYELAAQLHSRAQQICTVLYPGDATENGKLLRLKQQFFLCSASL 309 AKA D +L FN G Y A + A+ I VLYP D GK LRLKQ++F+ +A+L Sbjct: 247 AKA-PNDFNLKDFNVGGYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATL 305 Query: 310 QDIISRFHERSTTEGSRK-----WSEFPSKVAVQMNDTHPTLAIPELMRLLMDDNGLGWD 364 QDII RF +S+ G R + FP KVA+Q+NDTHP+LAIPELMR+L+D L WD Sbjct: 306 QDIIRRF--KSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELMRVLVDLERLDWD 363 Query: 365 EAWDVTSKTVAYTNHTVLPEALEKWSQSLMWKLLPRHMEIIEEIDKRFVQTIRDTRVDLE 424 +AW+VT KT AYTNHTVLPEALE+W L+ LLPRH++II EI++RF+ + Sbjct: 364 KAWEVTVKTCAYTNHTVLPEALERWPVHLLETLLPRHLQIIYEINQRFLNRVAAAFPGDV 423 Query: 425 DKISSLSILDNNPQKPVVRMANLCVVSSHTVNGVAQLHSDILKAELFADYVSIWPNKFQN 484 D++ +S+++ K + MA+LC+ SH VNGVA++HS+ILK +F D+ + P+KFQN Sbjct: 424 DRLRRMSLVEEGAVKR-INMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQN 482 Query: 485 KTNGITPRRWLRFCSPELSDIITKWLKTDKWITDLDLLTGLRQFADNEELQSEWASAKTA 544 KTNGITPRRWL C+P L++II + + +++I+DLD L L + D+E + A K Sbjct: 483 KTNGITPRRWLVLCNPGLAEIIAERI-GEEYISDLDQLRKLLSYVDDEAFIRDVAKVKQE 541 Query: 545 NKKRLAQYIERVTGVSIDPTSLFDIQVKRIHEYKRQLMNILGVVYRFKKLKEMKPEERKK 604 NK + A Y+ER V I+P SLFD+QVKRIHEYKRQL+N L V+ + ++K+ E K Sbjct: 542 NKLKFAAYLEREYKVHINPNSLFDVQVKRIHEYKRQLLNCLHVITLYNRIKK---EPNKF 598 Query: 605 TVPRTVMIGGKAFATYTNAKRIVKLVNDVGDVVNSDPEVNEYLKVVFVPNYNVTVAEMLI 664 VPRTVMIGGKA Y AK I+KL+ +GDVVN DP V + L+V+F+ NY V++AE +I Sbjct: 599 VVPRTVMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPVVGDRLRVIFLENYRVSLAEKVI 658 Query: 665 PGSELSQHISTAGMEASGTSNMKFALNGCLIIGTLDGANVEIREEVGEENFFLFGATADQ 724 P ++LS+ ISTAG EASGT NMKF LNG L IGT+DGANVE+ EE GEENFF+FG + Sbjct: 659 PAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENFFIFGMRVED 718 Query: 725 VPRLRKERE--DGLFKPDPRFEEAKQFVKSGVFGSYDYGPLLDSLEGNTGFGRGDYFLVG 782 V RL + + P + + + SG F D + D F V Sbjct: 719 VDRLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIV---NMLMHHDRFKVF 775 Query: 783 YDFPSYMDAQAKVDEAYKDRKGWLKMSILSTAGSGKFSSDRTIAQYAKEIWNIEAC---- 838 D+ Y+ Q +V YK+ + W +M I + A SGKFSSDRTIAQYA+EIW +E Sbjct: 776 ADYEEYVKCQERVSALYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGVEPSRQRL 835 Query: 839 PVP 841 P P Sbjct: 836 PAP 838 >5IKP-A nrPDB Length = 846 Score = 1250 bits (3234), Expect = 0.0, Method: Composition-based stats. Identities = 385/835 (46%), Positives = 523/835 (62%), Gaps = 27/835 (3%) Query: 14 EKISAKANPEADDATEIAGNIVYHAKYSPHFSPLK----FGPEQALYATAESLRDRLIQL 69 ++IS + D E+ + H HF+ +K P +A A ++RD L+ Sbjct: 15 KQISVRGLAGLGDVAEVRKSFNRHL----HFTLVKDRNVATPRDYFFALAHTVRDHLVGR 70 Query: 70 WNETYVHFNKVDPKQTYYLSMEYLQGRALTNAIGNLNLQGPYADALRTLGYELEEIAEQE 129 W T H+ + DPK+ YYLS+E+ GR L N + NL LQ +A+ LG +LEE+ E E Sbjct: 71 WIRTQQHYYERDPKRIYYLSLEFYMGRTLQNTMVNLGLQNACDEAIYQLGLDLEELEEIE 130 Query: 130 KDAALGNGGLGRLASCFLDSMATLNLPAWGYGLRYRHGLFKQIITKKGQEEIPEDWLEKF 189 +DA LGNGGLGRLA+CFLDSMATL L A+GYG+RY G+F Q I Q E +DWL Sbjct: 131 EDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEADDWLRYG 190 Query: 190 SPWEIVRHDVVFPVRFFGKVQVNPDGSRKWVDGDVVQALAYDVPIPGYGTKNTISLRLWE 249 +PWE R + + PV F+G+V+ PDG KW+D VV A+ YD P+PGY ++RLW Sbjct: 191 NPWEKARPEYMLPVHFYGRVEHTPDGV-KWLDTQVVLAMPYDTPVPGYKNNTVNTMRLWS 249 Query: 250 AKARAEDLDLFQFNEGEYELAAQLHSRAQQICTVLYPGDATENGKLLRLKQQFFLCSASL 309 AKA D L FN G+Y A + A+ I VLYP D GK LRLKQ++F+ +A+L Sbjct: 250 AKA-PNDFKLQDFNVGDYIEAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATL 308 Query: 310 QDIISRFHERSTTEGSRK-----WSEFPSKVAVQMNDTHPTLAIPELMRLLMDDNGLGWD 364 QDII RF +S+ G R + FP KVA+Q+NDTHP L+IPELMR+L+D + WD Sbjct: 309 QDIIRRF--KSSKFGCRDPVRTCFETFPDKVAIQLNDTHPALSIPELMRILVDVEKVDWD 366 Query: 365 EAWDVTSKTVAYTNHTVLPEALEKWSQSLMWKLLPRHMEIIEEIDKRFVQTIRDTRVDLE 424 +AW++T KT AYTNHTVLPEALE+W S+ KLLPRH+EII I++R + + Sbjct: 367 KAWEITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALFPGDV 426 Query: 425 DKISSLSILDNNPQKPVVRMANLCVVSSHTVNGVAQLHSDILKAELFADYVSIWPNKFQN 484 D++ +S+++ K + MA+LCV+ SH VNGVA++HS+I+K +F D+ + P KFQN Sbjct: 427 DRLRRMSVIEEGDCKR-INMAHLCVIGSHAVNGVARIHSEIVKQSVFKDFYELEPEKFQN 485 Query: 485 KTNGITPRRWLRFCSPELSDIITKWLKTDKWITDLDLLTGLRQFADNEELQSEWASAKTA 544 KTNGITPRRWL C+P L+D I + + ++++TDL L L +E + A K Sbjct: 486 KTNGITPRRWLLLCNPGLADTIVEKI-GEEFLTDLSQLKKLLPLVSDEVFIRDVAKVKQE 544 Query: 545 NKKRLAQYIERVTGVSIDPTSLFDIQVKRIHEYKRQLMNILGVVYRFKKLKEMKPEERKK 604 NK + + ++E+ V I+P+S+FD+ VKRIHEYKRQL+N L VV + ++K + K Sbjct: 545 NKLKFSAFLEKEYKVKINPSSMFDVHVKRIHEYKRQLLNCLHVVTLYNRIKR---DPAKA 601 Query: 605 TVPRTVMIGGKAFATYTNAKRIVKLVNDVGDVVNSDPEVNEYLKVVFVPNYNVTVAEMLI 664 VPRTVMIGGKA Y AK I+KLV +GDVVN DP V + LKV+F+ NY V++AE +I Sbjct: 602 FVPRTVMIGGKAAPGYHMAKLIIKLVTSIGDVVNHDPVVGDRLKVIFLENYRVSLAEKVI 661 Query: 665 PGSELSQHISTAGMEASGTSNMKFALNGCLIIGTLDGANVEIREEVGEENFFLFGATADQ 724 P ++LSQ ISTAG EASGT NMKF LNG L IGT+DGANVE+ EE G EN F+FG + Sbjct: 662 PAADLSQQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGAENLFIFGLRVED 721 Query: 725 VPRLRKERED--GLFKPDPRFEEAKQFVKSGVFGSYDYGPLLDSLEGNTGFGRGDYFLVG 782 V L ++ + + P ++A + SG F + D + D F V Sbjct: 722 VEALDRKGYNAREYYDHLPELKQAVDQISSGFFSPKEPDCFKDIV---NMLMHHDRFKVF 778 Query: 783 YDFPSYMDAQAKVDEAYKDRKGWLKMSILSTAGSGKFSSDRTIAQYAKEIWNIEA 837 D+ +YM QA+VD+ Y++ K W K I + A SGKFSSDRTI +YA+EIW +E Sbjct: 779 ADYEAYMQCQAQVDQLYRNPKEWTKKVIRNIACSGKFSSDRTITEYAREIWGVEP 833 >2ZB2-A nrPDB Length = 849 Score = 1225 bits (3169), Expect = 0.0, Method: Composition-based stats. Identities = 376/833 (45%), Positives = 518/833 (62%), Gaps = 23/833 (2%) Query: 14 EKISAKANPEADDATEIAGNIVYHAKYSPHFSPLK----FGPEQALYATAESLRDRLIQL 69 +IS + ++ E+ + H HF+ +K +A A ++RD L+ Sbjct: 14 RQISIRGIVGVENVAELKKSFNRHL----HFTLVKDRNVATTRDYYFALAHTVRDHLVGR 69 Query: 70 WNETYVHFNKVDPKQTYYLSMEYLQGRALTNAIGNLNLQGPYADALRTLGYELEEIAEQE 129 W T H+ PK+ YYLS+E+ GR L N + NL LQ +A+ LG ++EE+ E E Sbjct: 70 WIRTQQHYYDKCPKRVYYLSLEFYMGRTLQNTMINLGLQNACDEAIYQLGLDIEELEEIE 129 Query: 130 KDAALGNGGLGRLASCFLDSMATLNLPAWGYGLRYRHGLFKQIITKKGQEEIPEDWLEKF 189 +DA LGNGGLGRLA+CFLDSMATL L A+GYG+RY +G+F Q I Q E +DWL Sbjct: 130 EDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFNQKIRDGWQVEEADDWLRYG 189 Query: 190 SPWEIVRHDVVFPVRFFGKVQVNPDGSRKWVDGDVVQALAYDVPIPGYGTKNTISLRLWE 249 +PWE R + + PV F+GKV+ G+ KW+D VV AL YD P+PGY ++RLW Sbjct: 190 NPWEKSRPEFMLPVHFYGKVEHTNTGT-KWIDTQVVLALPYDTPVPGYMNNTVNTMRLWS 248 Query: 250 AKARAEDLDLFQFNEGEYELAAQLHSRAQQICTVLYPGDATENGKLLRLKQQFFLCSASL 309 A+A D +L FN G+Y A + A+ I VLYP D GK LRLKQ++F+ +A+L Sbjct: 249 ARA-PNDFNLRDFNVGDYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATL 307 Query: 310 QDIISRFHER---STTEGSRKWSEFPSKVAVQMNDTHPTLAIPELMRLLMDDNGLGWDEA 366 QDII RF ST + FP +VA+Q+NDTHP LAIPELMR+ +D L W +A Sbjct: 308 QDIIRRFKASKFGSTRGAGTVFDAFPDQVAIQLNDTHPALAIPELMRIFVDIEKLPWSKA 367 Query: 367 WDVTSKTVAYTNHTVLPEALEKWSQSLMWKLLPRHMEIIEEIDKRFVQTIRDTRVDLEDK 426 W++T KT AYTNHTVLPEALE+W L+ KLLPRH+EII EI+++ + I D+ Sbjct: 368 WELTQKTFAYTNHTVLPEALERWPVDLVEKLLPRHLEIIYEINQKHLDRIVALFPKDVDR 427 Query: 427 ISSLSILDNNPQKPVVRMANLCVVSSHTVNGVAQLHSDILKAELFADYVSIWPNKFQNKT 486 + +S+++ K + MA+LC+V SH VNGVA++HSDI+K ++F D+ + P+KFQNKT Sbjct: 428 LRRMSLIEEEGSKR-INMAHLCIVGSHAVNGVAKIHSDIVKTKVFKDFSELEPDKFQNKT 486 Query: 487 NGITPRRWLRFCSPELSDIITKWLKTDKWITDLDLLTGLRQFADNEELQSEWASAKTANK 546 NGITPRRWL C+P L+++I + + + ++ DL LT L F ++ E A K NK Sbjct: 487 NGITPRRWLLLCNPGLAELIAEKI-GEDYVKDLSQLTKLHSFLGDDVFLRELAKVKQENK 545 Query: 547 KRLAQYIERVTGVSIDPTSLFDIQVKRIHEYKRQLMNILGVVYRFKKLKEMKPEERKKTV 606 + +Q++E V I+P+S+FD+QVKRIHEYKRQL+N L V+ + ++K+ + +K V Sbjct: 546 LKFSQFLETEYKVKINPSSMFDVQVKRIHEYKRQLLNCLHVITMYNRIKK---DPKKLFV 602 Query: 607 PRTVMIGGKAFATYTNAKRIVKLVNDVGDVVNSDPEVNEYLKVVFVPNYNVTVAEMLIPG 666 PRTV+IGGKA Y AK I+KL+ V DVVN+DP V LKV+F+ NY V++AE +IP Sbjct: 603 PRTVIIGGKAAPGYHMAKMIIKLITSVADVVNNDPMVGSKLKVIFLENYRVSLAEKVIPA 662 Query: 667 SELSQHISTAGMEASGTSNMKFALNGCLIIGTLDGANVEIREEVGEENFFLFGATADQVP 726 ++LS+ ISTAG EASGT NMKF LNG L IGT+DGANVE+ EE GEEN F+FG D V Sbjct: 663 TDLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRIDDVA 722 Query: 727 RLRKERED--GLFKPDPRFEEAKQFVKSGVFGSYDYGPLLDSLEGNTGFGRGDYFLVGYD 784 L K+ + ++ P + + +G F D + D F V D Sbjct: 723 ALDKKGYEAKEYYEALPELKLVIDQIDNGFFSPKQPDLFKDII---NMLFYHDRFKVFAD 779 Query: 785 FPSYMDAQAKVDEAYKDRKGWLKMSILSTAGSGKFSSDRTIAQYAKEIWNIEA 837 + +Y+ Q KV + Y + K W M + + A SGKFSSDRTI +YA+ IWN+E Sbjct: 780 YEAYVKCQDKVSQLYMNPKAWNTMVLKNIAASGKFSSDRTIKEYAQNIWNVEP 832 >1YGP-A nrPDB Length = 879 Score = 1078 bits (2788), Expect = 0.0, Method: Composition-based stats. Identities = 377/847 (44%), Positives = 526/847 (62%), Gaps = 44/847 (5%) Query: 27 ATEIAGNIVYHAKYSPHFSPLKFGPEQALYATAESLRDRLIQLWNETYVHFNKVDPKQTY 86 A + + H + + S A A + S+RD L+ WN+T F DPK+ Y Sbjct: 41 AEDFQDRFIDHVETTLARSLYNCDDMVAYEAASMSIRDNLVIDWNKTQQKFTTRDPKRVY 100 Query: 87 YLSMEYLQGRALTNAIGNLNLQGP-------------YADALRTLGYELEEIAEQEKDAA 133 YLS+E+L GRAL NA+ N+ ++ P AL LG++LE++ +QE DA Sbjct: 101 YLSLEFLMGRALDNALINMKIEDPEDPAASKGKPREMIKGALDELGFKLEDVLDQEPDAG 160 Query: 134 LGNGGLGRLASCFLDSMATLNLPAWGYGLRYRHGLFKQIITKKGQEEIPEDWLEKFSPWE 193 LGNGGLGRLA+CF+DSMAT +PAWGYGLRY +G+F Q I Q E P+ WL +PWE Sbjct: 161 LGNGGLGRLAACFVDSMATEGIPAWGYGLRYEYGIFAQKIIDGYQVETPDYWLNSGNPWE 220 Query: 194 IVRHDVVFPVRFFGKVQVNPDGSR------KWVDGDVVQALAYDVPIPGYGTKNTISLRL 247 I R++V PV F+G V P+G + +W+ G+ V A+AYD P+PG+ T N +LRL Sbjct: 221 IERNEVQIPVTFYGYVD-RPEGGKTTLSASQWIGGERVLAVAYDFPVPGFKTSNVNNLRL 279 Query: 248 WEAKARAEDLDLFQFNEGEYELAAQLHSRAQQICTVLYPGDATENGKLLRLKQQFFLCSA 307 W+A+ E DL +FN G+Y+ + RA+ I VLYP D GK LRLKQQ+F C+A Sbjct: 280 WQARPTTE-FDLNKFNNGDYKNSVAQQQRAESITAVLYPNDNFAQGKELRLKQQYFWCAA 338 Query: 308 SLQDIISRFHERSTTEGSRKWSEFPSKVAVQMNDTHPTLAIPELMRLLMDDNGLGWDEAW 367 SL DI+ RF + R W+EFP +VA+Q+NDTHPTLAI EL R+L+D L W EAW Sbjct: 339 SLHDILRRF-----KKSKRPWTEFPDQVAIQLNDTHPTLAIVELQRVLVDLEKLDWHEAW 393 Query: 368 DVTSKTVAYTNHTVLPEALEKWSQSLMWKLLPRHMEIIEEIDKRFVQTIRDTRVDLEDKI 427 D+ +KT AYTNHTV+ EALEKW + L LLPRH+EII +I+ F++ + D + Sbjct: 394 DIVTKTFAYTNHTVMQEALEKWPRRLFGHLLPRHLEIIYDINWFFLEDVAKKFPKDVDLL 453 Query: 428 SSLSILDNNPQKPVVRMANLCVVSSHTVNGVAQLHSDILKAELFADYVSIW-PNKFQNKT 486 S +SI++ N + +RMA L +V SH VNGV +LHS+++K +F D++ + P+KF N T Sbjct: 454 SRISIIEENSPERQIRMAFLAIVGSHKVNGVVELHSELIKTTIFKDFIKFYGPSKFVNVT 513 Query: 487 NGITPRRWLRFCSPELSDIITKWLK--TDKWITDLDLLTGLRQFADNEELQSEWASAKTA 544 NGITPRRWL+ +P L+ +I++ L T++++ D+ LT L ++ +++E +W K Sbjct: 514 NGITPRRWLKQANPSLAKLISETLNDPTEEYLLDMAKLTQLEKYVEDKEFLKKWNQVKLN 573 Query: 545 NKKRLAQYIERVT-GVSID-----PTSLFDIQVKRIHEYKRQLMNILGVVYRFKKLKEM- 597 NK RL I++ GV I +LFD+QVKRIHEYKRQ +N+ G++YR+ +K M Sbjct: 574 NKIRLVDLIKKENDGVDIINREYLDDTLFDMQVKRIHEYKRQQLNVFGIIYRYLAMKNML 633 Query: 598 ----KPEERKKTVPRTV-MIGGKAFATYTNAKRIVKLVNDVGDVVNSDPEVNEYLKVVFV 652 EE + PR V + GGK+ Y AK I+KL+N V D+VN+D + LKVVFV Sbjct: 634 KNGASIEEVARKYPRKVSIFGGKSAPGYYMAKLIIKLINCVADIVNNDESIEHLLKVVFV 693 Query: 653 PNYNVTVAEMLIPGSELSQHISTAGMEASGTSNMKFALNGCLIIGTLDGANVEIREEVGE 712 +YNV+ AE++IP S+LS+HISTAG EASGTSNMKF +NG LIIGT+DGANVEI E+GE Sbjct: 694 ADYNVSKAEIIIPASDLSEHISTAGTEASGTSNMKFVMNGGLIIGTVDGANVEITREIGE 753 Query: 713 ENFFLFGATADQVPRLRKEREDGLFKPDPRFEEAKQFVKSGVFGSYDYGPLLDSLEGNTG 772 +N FLFG ++ V LR + + +++SG F + + ++ Sbjct: 754 DNVFLFGNLSENVEELRYNHQYHPQDLPSSLDSVLSYIESGQFSPENPNEFKPLV--DSI 811 Query: 773 FGRGDYFLVGYDFPSYMDAQAKVDEAYKDRK-GWLKMSILSTAGSGKFSSDRTIAQYAKE 831 GDY+LV DF SY+ VD+ + +++ WLK S+LS A G FSSDR I +Y+ Sbjct: 812 KYHGDYYLVSDDFESYLATHELVDQEFHNQRSEWLKKSVLSLANVGFFSSDRCIEEYSDT 871 Query: 832 IWNIEAC 838 IWN+E Sbjct: 872 IWNVEPV 878 >1AHP-A nrPDB Length = 797 Score = 1069 bits (2764), Expect = 0.0, Method: Composition-based stats. Identities = 342/793 (43%), Positives = 480/793 (60%), Gaps = 29/793 (3%) Query: 45 SPLKFGPEQALYATAESLRDRLIQLWNETYVHFNK--VDPKQTYYLSMEYLQGRALTNAI 102 S + P Q A +E+L + L F K + + Y+SME+L GR N + Sbjct: 26 SAAEMTPRQWWLAVSEALAEML------RAQPFAKPVANQRHVNYISMEFLIGRLTGNNL 79 Query: 103 GNLNLQGPYADALRTLGYELEEIAEQEKDAALGNGGLGRLASCFLDSMATLNLPAWGYGL 162 NL D+L+ L ++ E+E D ALG GGLGRLA+CFLDSMAT+ A GYGL Sbjct: 80 LNLGWYQDVQDSLKAYDINLTDLLEEEIDPALGAGGLGRLAACFLDSMATVGQSATGYGL 139 Query: 163 RYRHGLFKQIITKKGQEEIPEDWLEKFSPWEIVRHDVVFPVRFFGKVQVNPDGSRKWVDG 222 Y++GLF+Q Q E P+DW PW RH+ V+ V DG +W Sbjct: 140 NYQYGLFRQSFVDGKQVEAPDDWHRSNYPW--FRHNEALDVQVGIGGAVTKDG--RWEPE 195 Query: 223 DVVQALAYDVPIPGYGTKNTISLRLWEAKARAEDLDLFQFNEGEYELAAQLHSRAQQICT 282 + A+D+P+ GY LRLW+A A DL +FN+G++ A Q A+++ Sbjct: 196 FTITGQAWDLPVVGYRNGVAQPLRLWQA-THAHPFDLTKFNDGDFLRAEQQGINAEKLTK 254 Query: 283 VLYPGDATENGKLLRLKQQFFLCSASLQDIISRFHERSTTEGSRKWSEFPSKVAVQMNDT 342 VLYP D GK LRL QQ+F C+ S+ DI+ R H R+ E +Q+NDT Sbjct: 255 VLYPNDNHTAGKKLRLMQQYFQCACSVADILRRHHL-----AGRELHELADYEVIQLNDT 309 Query: 343 HPTLAIPELMRLLMDDNGLGWDEAWDVTSKTVAYTNHTVLPEALEKWSQSLMWKLLPRHM 402 HPT+AIPEL+R+L+D++ + WD+AW +TSKT AYTNHT++PEALE+W L+ LLPRHM Sbjct: 310 HPTIAIPELLRVLIDEHQMSWDDAWAITSKTFAYTNHTLMPEALERWDVKLVKGLLPRHM 369 Query: 403 EIIEEIDKRFVQTIRDTRVDLEDKISSLSILDNNPQKPVVRMANLCVVSSHTVNGVAQLH 462 +II EI+ RF + T E + L+++ + V MANLCVV VNGVA LH Sbjct: 370 QIINEINTRFKTLVEKTWPGDEKVWAKLAVVHDKQ----VHMANLCVVGGFAVNGVAALH 425 Query: 463 SDILKAELFADYVSIWPNKFQNKTNGITPRRWLRFCSPELSDIITKWLKTDKWITDLDLL 522 SD++ +LF +Y +WPNKF N TNGITPRRW++ C+P L+ ++ K L+ + W DLD L Sbjct: 426 SDLVVKDLFPEYHQLWPNKFHNVTNGITPRRWIKQCNPALAALLDKSLQKE-WANDLDQL 484 Query: 523 TGLRQFADNEELQSEWASAKTANKKRLAQYIERVTGVSIDPTSLFDIQVKRIHEYKRQLM 582 L + AD+ + + + K ANK RLA++++ TG+ I+P ++FDIQ+KR+HEYKRQ + Sbjct: 485 INLVKLADDAKFRDLYRVIKQANKVRLAEFVKVRTGIDINPQAIFDIQIKRLHEYKRQHL 544 Query: 583 NILGVVYRFKKLKEMKPEERKKTVPRTVMIGGKAFATYTNAKRIVKLVNDVGDVVNSDPE 642 N+L ++ +K+++E +R VPR + G KA Y AK I+ +N V DV+N+DP Sbjct: 545 NLLRILALYKEIRENPQADR---VPRVFLFGAKAAPGYYLAKNIIFAINKVADVINNDPL 601 Query: 643 VNEYLKVVFVPNYNVTVAEMLIPGSELSQHISTAGMEASGTSNMKFALNGCLIIGTLDGA 702 V + LKVVF+P+Y V+ AE LIP +++S+ ISTAG EASGT NMK ALNG L +GTLDGA Sbjct: 602 VGDKLKVVFLPDYCVSAAEKLIPAADISEQISTAGKEASGTGNMKLALNGALTVGTLDGA 661 Query: 703 NVEIREEVGEENFFLFGATADQVPRLRKEREDGL--FKPDPRFEEAKQFVKSGVFGSYDY 760 NVEI E+VGEEN F+FG T QV + + D + K D + + ++SG + D Sbjct: 662 NVEIAEKVGEENIFIFGHTVKQVKAILAKGYDPVKWRKKDKVLDAVLKELESGKYSDGDK 721 Query: 761 GPLLDSLEGNTGFGRGDYFLVGYDFPSYMDAQAKVDEAYKDRKGWLKMSILSTAGSGKFS 820 D + + G GD +LV DF +Y++AQ +VD Y+D++ W + +IL+TA G FS Sbjct: 722 HAF-DQMLHSIGKQGGDPYLVMADFAAYVEAQKQVDVLYRDQEAWTRAAILNTARCGMFS 780 Query: 821 SDRTIAQYAKEIW 833 SDR+I Y IW Sbjct: 781 SDRSIRDYQARIW 793 >2C4M-A nrPDB Length = 796 Score = 1055 bits (2729), Expect = 0.0, Method: Composition-based stats. Identities = 353/819 (43%), Positives = 489/819 (59%), Gaps = 41/819 (5%) Query: 28 TEIAGNIVYHAKYSPHFSPLKFGPEQALYATAESLRDRLIQLWNETYVHFNKVDPKQTYY 87 + G+ V A +P + + ++++R+ W T + +Q +Y Sbjct: 10 AALVGSHVRAAAGTP---ADLATDRKFWTGLSRAVQERIADDWERTREAYGAA--RQQHY 64 Query: 88 LSMEYLQGRALTNAIGNLNLQGPYADALRTLGYELEEIAEQEKDAALGNGGLGRLASCFL 147 S E+L GRAL N + NL L A A R LG+EL +I E E DAALGNGGLGRLA+CFL Sbjct: 65 FSAEFLMGRALLNNLTNLGLVDEAAAATRELGHELTDILEIENDAALGNGGLGRLAACFL 124 Query: 148 DSMATLNLPAWGYGLRYRHGLFKQIITKKGQEEIPEDWLEKFSPWEIVRHDVVFPVRFFG 207 DS T + P GYGL YR GLF+Q + Q E P+ W E+ P+ I R V F Sbjct: 125 DSAVTQDYPVTGYGLLYRFGLFRQSFNEGFQVEKPDPWREEEYPFTIRRASDQLVVCF-- 182 Query: 208 KVQVNPDGSRKWVDGDVVQALAYDVPIPGYGTKNTISLRLWEAKARAEDLDLFQFNEGEY 267 D +A+ YD+PI GYGT N +LRLW+A+ E+ D FN + Sbjct: 183 -------------DDMKTRAIPYDMPITGYGTHNVGTLRLWKAEP-WEEFDYDAFNAQRF 228 Query: 268 ELAAQLHSRAQQICTVLYPGDATENGKLLRLKQQFFLCSASLQDIISRFHERSTTEGSRK 327 A R IC VLYP D T GK LR++QQ+F SASLQ +I + + Sbjct: 229 TDAIIERERVSDICRVLYPNDTTYEGKKLRVRQQYFFTSASLQAMI-----QDHLAHHKD 283 Query: 328 WSEFPSKVAVQMNDTHPTLAIPELMRLLMDDNGLGWDEAWDVTSKTVAYTNHTVLPEALE 387 S F +VQ+NDTHP LAIPELMRLLMD++ +GW+E+W + SKT AYTNHTVL EALE Sbjct: 284 LSNFAEFHSVQLNDTHPVLAIPELMRLLMDEHDMGWEESWAIVSKTFAYTNHTVLTEALE 343 Query: 388 KWSQSLMWKLLPRHMEIIEEIDKRFVQTIRDTRVDLEDKISSLSILDNNPQKPVVRMANL 447 +W + + +L R EII EID+RF + E+ I+ ++ + Q V MA + Sbjct: 344 QWDEQIFQQLFWRVWEIIAEIDRRFRLERAADGL-DEETINRMAPI----QHGTVHMAWI 398 Query: 448 CVVSSHTVNGVAQLHSDILKAELFADYVSIWPNKFQNKTNGITPRRWLRFCSPELSDIIT 507 +++++NGVA LH++I+KAE AD+ ++WP KF NKTNG+TPRRWLR +P LSD++T Sbjct: 399 ACYAAYSINGVAALHTEIIKAETLADWYALWPEKFNNKTNGVTPRRWLRMINPGLSDLLT 458 Query: 508 KWLKTDKWITDLDLLTGLRQFADNEELQSEWASAKTANKKRLAQYIERVTGVSIDPTSLF 567 + +D W+TDLD L LR +AD++ + E + K ANK+ A++I G+ IDP S+F Sbjct: 459 RLSGSDDWVTDLDELKKLRSYADDKSVLEELRAIKAANKQDFAEWILERQGIEIDPESIF 518 Query: 568 DIQVKRIHEYKRQLMNILGVVYRFKKLKEMKPEERKKTVP-RTVMIGGKAFATYTNAKRI 626 D+Q+KR+HEYKRQLMN L V+ + ++K E+ +P RTV+ G KA Y AK I Sbjct: 519 DVQIKRLHEYKRQLMNALYVLDLYFRIK----EDGLTDIPARTVIFGAKAAPGYVRAKAI 574 Query: 627 VKLVNDVGDVVNSDPEVNEYLKVVFVPNYNVTVAEMLIPGSELSQHISTAGMEASGTSNM 686 +KL+N + D+VN+DPEV+ LKVVFV NYNV+ AE ++P S++S+ ISTAG EASGTSNM Sbjct: 575 IKLINSIADLVNNDPEVSPLLKVVFVENYNVSPAEHILPASDVSEQISTAGKEASGTSNM 634 Query: 687 KFALNGCLIIGTLDGANVEIREEVGEENFFLFGATADQVPRLRK-EREDGLFKPDPRFEE 745 KF +NG L +GT+DGANVEI + VGEEN ++FGA +++P LR+ + L++ P + Sbjct: 635 KFMMNGALTLGTMDGANVEIVDSVGEENAYIFGARVEELPALRESYKPYELYETVPGLKR 694 Query: 746 AKQFVKSGVFGSYDYGPLLD---SLEGNTGFGRGDYFLVGYDFPSYMDAQAKVDEAY-KD 801 A + +G + G D SL G D + V DF Y + + ++ Y D Sbjct: 695 ALDALDNGTLNDNNSGLFYDLKHSLIHGYGKDASDTYYVLGDFADYRETRDRMAADYASD 754 Query: 802 RKGWLKMSILSTAGSGKFSSDRTIAQYAKEIWNIEACPV 840 GW +M+ ++ SG+FSSDRTI YA EIW +E P Sbjct: 755 PLGWARMAWINICESGRFSSDRTIRDYATEIWKLEPTPA 793 >4L22-A nrPDB Length = 758 Score = 916 bits (2368), Expect = 0.0, Method: Composition-based stats. Identities = 281/762 (36%), Positives = 415/762 (54%), Gaps = 65/762 (8%) Query: 83 KQTYYLSMEYLQGRALTNAIGNLNLQGPYADALRTLGYELEEIAEQEKDAALGNGGLGRL 142 ++ YY+S E+L G+ L+N + NL L D L G + ++ + E + +LGNGGLGRL Sbjct: 50 RKVYYISAEFLIGKLLSNNLINLGLYKTVKDELAAAGKSISQVEDVELEPSLGNGGLGRL 109 Query: 143 ASCFLDSMATLNLPAWGYGLRYRHGLFKQIITKKGQEEIPEDWLEKFSPWEIVRHDVVFP 202 ASCF+DSMATL + G GL Y GLFKQ+ QE P W+E S Sbjct: 110 ASCFIDSMATLGINGEGVGLNYHCGLFKQVFRDNQQEAEPNYWIEDDS------------ 157 Query: 203 VRFFGKVQVNPDGSRKWVDGDVVQALAYDVPIPGYGTKNTISL--RLWEAKARAEDLDLF 260 W+ V A++YDVP + K+ + L K L+LF Sbjct: 158 ----------------WL---VPTAISYDVPFRDFTLKSKLDRIDILGYHKDSKNYLNLF 198 Query: 261 QFNEGEYELAA-----QLHSRAQQICTVLYPGDATENGKLLRLKQQFFLCSASLQDIISR 315 + +Y L + + LYP D+ +NG+LLR+ QQ+F+ S + Q +I Sbjct: 199 DIDGLDYGLIKDGITFDKTEIKKNLTLFLYPDDSDKNGELLRIYQQYFMVSNAAQLLIDE 258 Query: 316 FHERSTTEGSRKWSEFPSKVAVQMNDTHPTLAIPELMRLLMDDNGLGWDEAWDVTSKTVA 375 ER + + VQ+NDTHP++ IPEL+RLL + +GL + EA D+ + Sbjct: 259 ALERGS-----NLHDLADYAYVQINDTHPSMVIPELIRLLNEKHGLDFYEAVDIVKNMIG 313 Query: 376 YTNHTVLPEALEKWSQSLMWKLLPRHMEIIEEIDKRFVQTIRDTRVDLEDKISSLSILDN 435 YTNHT+L EALEKW + +++P + IIE +D+ +D ++ I+D Sbjct: 314 YTNHTILAEALEKWPLEYLNEVVPHLVTIIEHLDRIVRSQYKD---------DAVQIIDR 364 Query: 436 NPQKPVVRMANLCVVSSHTVNGVAQLHSDILKAELFADYVSIWPNKFQNKTNGITPRRWL 495 + + V MA++ + S +VNGVA LH+DILK + I+P KF NKTNGIT RRWL Sbjct: 365 DDR---VHMAHMDIHFSTSVNGVAALHTDILKNSELKPFYDIYPEKFNNKTNGITFRRWL 421 Query: 496 RFCSPELSDIITKWLKTDKWITDLDLLTGLRQFADNEELQSEWASAKTANKKRLAQYIER 555 F + +L+ I K L + ++ D L L FAD++ + + A K NK L +Y++ Sbjct: 422 EFANQDLAAYI-KELIGEGYLEDATELEKLLAFADDKTVHEQLAKIKFNNKLALKRYLKE 480 Query: 556 VTGVSIDPTSLFDIQVKRIHEYKRQLMNILGVVYRFKKLKEMKPEERKKTVPRTVMIGGK 615 G+++D S+ D Q+KR HEYKRQ MN L V+Y++ ++K+ +RK TV+ GGK Sbjct: 481 NKGINLDENSIIDTQIKRFHEYKRQQMNALYVIYKYLEIKKGNLPKRK----ITVIFGGK 536 Query: 616 AFATYTNAKRIVKLVNDVGDVVNSDPEVNEYLKVVFVPNYNVTVAEMLIPGSELSQHIST 675 A YT A+ I+ L+ + +++N+DP+V+ YL V V NYNVTVAE LIP +++S+ IS Sbjct: 537 AAPAYTIAQDIIHLILCLSELINNDPDVSPYLNVFLVENYNVTVAEKLIPATDISEQISL 596 Query: 676 AGMEASGTSNMKFALNGCLIIGTLDGANVEIREEVGEENFFLFGATADQVPRLRKERED- 734 A EASGT NMKF LNG L +GT+DGANVEI E VG +N ++FG +D + L + Sbjct: 597 ASKEASGTGNMKFMLNGALTLGTMDGANVEIAELVGSDNIYIFGKDSDTIIDLYDKGTYV 656 Query: 735 --GLFKPDPRFEEAKQFVKSGVFGSYDYGPLLDSLEGNTGFGRGDYFLVGYDFPSYMDAQ 792 + + +EA F+ S + L+ L D+F+ D Y+ + Sbjct: 657 SKDYYTNNAVIKEAVDFIVSKDVLALGKKERLERLYHE--LINKDWFMTLIDLKEYIAKK 714 Query: 793 AKVDEAYKDRKGWLKMSILSTAGSGKFSSDRTIAQYAKEIWN 834 ++ Y+D+ W K I + A +G FSSDRTI QY K+IW+ Sbjct: 715 EEMLADYEDQNVWNKKVIQNIAKAGFFSSDRTIQQYDKDIWH 756 >5LR8-A nrPDB Length = 938 Score = 630 bits (1624), Expect = 0.0, Method: Composition-based stats. Identities = 274/461 (59%), Positives = 344/461 (74%), Gaps = 4/461 (0%) Query: 382 LPEALEKWSQSLMWKLLPRHMEIIEEIDKRFVQTIRDTRVDLEDKISSLSILDNNPQKPV 441 + EA EK + +L E E D + E + + D V Sbjct: 469 IAEADEKTESQEVENILSETTEKKAESDSEEAPDAEKEDPEYE--LDPFAKYDPQFP-RV 525 Query: 442 VRMANLCVVSSHTVNGVAQLHSDILKAELFADYVSIWPNKFQNKTNGITPRRWLRFCSPE 501 VRMANLCVV H+VNGVA++HS+I+K ++F + +WP KFQNKTNG+TPRRW+RFC+PE Sbjct: 526 VRMANLCVVGGHSVNGVAEIHSEIVKQDVFNSFYEMWPTKFQNKTNGVTPRRWIRFCNPE 585 Query: 502 LSDIITKWLKTDKWITDLDLLTGLRQFADNEELQSEWASAKTANKKRLAQYIERVTGVSI 561 LS II+KW+ +D WI + D L GL++FAD+E+LQSEW +AK NK ++ I TG + Sbjct: 586 LSTIISKWIGSDDWILNTDKLAGLKKFADDEDLQSEWRTAKRNNKMKVVSLIRDKTGYIV 645 Query: 562 DPTSLFDIQVKRIHEYKRQLMNILGVVYRFKKLKEMKPEERKK-TVPRTVMIGGKAFATY 620 P ++FD+QVKRIHEYKRQL+NILG+VYR+KK+KEM ++R+K VPR + GGKAFATY Sbjct: 646 SPDAMFDVQVKRIHEYKRQLLNILGIVYRYKKMKEMSAKDRRKSFVPRVCIFGGKAFATY 705 Query: 621 TNAKRIVKLVNDVGDVVNSDPEVNEYLKVVFVPNYNVTVAEMLIPGSELSQHISTAGMEA 680 AKRIVK + DV VN DP++ + LKVVFVP+YNV+VAE LIP SELSQHISTAGMEA Sbjct: 706 VQAKRIVKFITDVAATVNYDPDIGDLLKVVFVPDYNVSVAETLIPASELSQHISTAGMEA 765 Query: 681 SGTSNMKFALNGCLIIGTLDGANVEIREEVGEENFFLFGATADQVPRLRKEREDGLFKPD 740 SGTSNMKFA+NGCL+IGTLDGANVEIREEVGEENFFLFGA A ++ LR+ER +G F PD Sbjct: 766 SGTSNMKFAMNGCLLIGTLDGANVEIREEVGEENFFLFGAHAPEIAGLRQERAEGKFVPD 825 Query: 741 PRFEEAKQFVKSGVFGSYDYGPLLDSLEGNTGFGRGDYFLVGYDFPSYMDAQAKVDEAYK 800 RFEE K++V+SGVFG+ +Y L+ SLEGN G+GR DYFLVG DFPSY++ Q KVDEAY+ Sbjct: 826 LRFEEVKEYVRSGVFGTSNYDELMGSLEGNEGYGRADYFLVGKDFPSYIECQEKVDEAYR 885 Query: 801 DRKGWLKMSILSTAGSGKFSSDRTIAQYAKEIWNIEACPVP 841 D+K W +MSIL+TAGS KFSSDRTI +YAK+IW+I +P Sbjct: 886 DQKLWTRMSILNTAGSPKFSSDRTIHEYAKDIWDISPVIMP 926 Score = 606 bits (1563), Expect = e-173, Method: Composition-based stats. Identities = 255/422 (60%), Positives = 314/422 (74%), Gaps = 7/422 (1%) Query: 26 DATEIAGNIVYHAKYSPHFSPLKFGPEQALYATAESLRDRLIQLWNETYVHFNKVDPKQT 85 D++ IA NI +HA ++P FSP P +A +ATA+S+ D LI WN TY ++NKV+ KQ Sbjct: 28 DSSAIASNIQHHADFTPLFSPEHSSPLKAYHATAKSVFDSLIMNWNATYDYYNKVNAKQA 87 Query: 86 YYLSMEYLQGRALTNAIGNLNLQGPYADALRTLGYELEEIAEQEKDAALGNGGLGRLASC 145 YYLSME+LQGRALTNAIGNL L G YA+AL+ LG+ LE++A QE D ALGNGGLGRLASC Sbjct: 88 YYLSMEFLQGRALTNAIGNLELTGQYAEALKQLGHNLEDVASQEPDPALGNGGLGRLASC 147 Query: 146 FLDSMATLNLPAWGYGLRYRHGLFKQIITKKGQEEIPEDWLEKFSPWEIVRHDVVFPVRF 205 FLDS+ATLN PAWGYGLRYR+GLFKQIITK GQEE+ E+WLE +PWEIVR+DV +PV+F Sbjct: 148 FLDSLATLNYPAWGYGLRYRYGLFKQIITKDGQEEVAENWLEMGNPWEIVRNDVSYPVKF 207 Query: 206 FGKVQVNPDGSRKWVDGDVVQALAYDVPIPGYGTKNTISLRLWEAKARAEDLDLFQFNEG 265 +GKV DG + W+ G+ ++A+A+DVPIPGY TK T +LRLW +++ DL FN G Sbjct: 208 YGKVVEGTDGRKHWIGGENIKAVAHDVPIPGYKTKTTNNLRLWSTTVPSQNFDLGAFNAG 267 Query: 266 EYELAAQLHSRAQQICTVLYPGDATENGKLLRLKQQFFLCSASLQDIISRFHERSTTEGS 325 ++ A + H A++IC VLYPGD + GK+LRLKQQ+ LCSASLQDIISRF R+ S Sbjct: 268 DHAKANEAHLNAEKICHVLYPGDESSEGKILRLKQQYTLCSASLQDIISRFESRAGD--S 325 Query: 326 RKWSEFPSKVAVQMNDTHPTLAIPELMRLLMDDNGLGWDEAWDVTSKTVAYTNHTVLPEA 385 W +FPSKVAVQMNDTHPTL IPELMR+LMD GL W+EAW +T +TVAYTNHTVLPEA Sbjct: 326 LNWEDFPSKVAVQMNDTHPTLCIPELMRILMDIKGLSWNEAWSITERTVAYTNHTVLPEA 385 Query: 386 LEKWSQSLMWKLLPRHMEIIEEIDKRFVQTIRDTRVD-----LEDKISSLSILDNNPQKP 440 LEKWS +M KLLPRH+EIIE ID+ + I L+ K+ + ILDN Sbjct: 386 LEKWSLDIMQKLLPRHVEIIETIDEELMNNIVSKYGTADISLLKQKLKDMRILDNVDLPA 445 Query: 441 VV 442 V Sbjct: 446 SV 447 >4KMA-A nrPDB Length = 498 Score = 33.9 bits (76), Expect = 0.29, Method: Composition-based stats. Identities = 14/76 (18%), Positives = 24/76 (31%), Gaps = 4/76 (5%) Query: 713 ENFFLFGATADQVPRLRKEREDGLFKPDPRFEEAKQFVKSGVFGSYDYGPLLDSLEGNTG 772 EN + GA + + KP P + + G PL + Sbjct: 18 ENLYFQGAMDPEFMAEANLDKKPEVKPPPGLKAIIDHL--GQVYPNQPNPLQVTTLLKYW 75 Query: 773 FGRGDY--FLVGYDFP 786 G D ++ Y++P Sbjct: 76 LGGQDPLDYISMYNYP 91 >3G33-B nrPDB Length = 306 Score = 33.9 bits (76), Expect = 0.34, Method: Composition-based stats. Identities = 11/38 (28%), Positives = 15/38 (39%) Query: 370 TSKTVAYTNHTVLPEALEKWSQSLMWKLLPRHMEIIEE 407 K YT+H V P L W ++ KL +I Sbjct: 135 IEKLCIYTDHAVSPRQLRDWEVLVLGKLKWDLAAVIAH 172 >5IM3-A nrPDB Length = 963 Score = 32.0 bits (71), Expect = 1.1, Method: Composition-based stats. Identities = 35/169 (20%), Positives = 62/169 (36%), Gaps = 13/169 (7%) Query: 429 SLSILDNNPQKPVVRMANLCVVSSHTVNGVAQLHSDILKAELFADYVSIWPNKFQNKTNG 488 S+ I + + M L + S G+A++ +++ E + K N T Sbjct: 147 SIRITRADGSLSPLDMGRLNTIISEACEGLAEVDGALIERETLKNLYDGVAEKDVN-TAL 205 Query: 489 ITPRRWLRFCSPELSDIITKWLKTDKWITDLDLLTGLRQFADNEELQSEWASAKTANKKR 548 + R L P S +T L D + G+ + A + E+ +A A Sbjct: 206 VMTARTLVEREPNYS-YVTARLLMDTLRAEALGFLGVAESATHHEMAELYAKA------- 257 Query: 549 LAQYIERVTGVSIDPTSL--FDIQV--KRIHEYKRQLMNILGVVYRFKK 593 L YIE+ + L FD++ K I + Q LG+ + + Sbjct: 258 LPAYIEKGAEFELVDAKLKEFDLEKLGKAIDHERDQQFTYLGLQTLYDR 306 >1TUE-B nrPDB Length = 218 Score = 31.6 bits (70), Expect = 1.4, Method: Composition-based stats. Identities = 18/117 (15%), Positives = 42/117 (35%), Gaps = 14/117 (11%) Query: 722 ADQVPRLRKEREDGLFKPDPRFEEAKQFVKSGVFGSYDYGPLLDSLEGNTGFGRGDYFLV 781 ++++ L+ + D + Q+ ++ + E Sbjct: 12 SERLSALQDKIIDHYENDSKDIDSQIQYW---QLIRWENAIFFAAREHGIQTLNHQV--- 65 Query: 782 GYDFPSYMDAQAKVDEAYKDRKGWLKMSILSTAGSGKFSSDRTIAQYAKEIWNIEAC 838 P+Y +++K +A + L+M++ A S + D T+ +E+WN E Sbjct: 66 ---VPAYNISKSKAHKAIE-----LQMALQGLAQSAYKTEDWTLQDTCEELWNTEPT 114 >1J2Z-A nrPDB Length = 270 Score = 31.6 bits (70), Expect = 1.7, Method: Composition-based stats. Identities = 29/112 (25%), Positives = 42/112 (37%), Gaps = 7/112 (6%) Query: 358 DNGLGWDEAWDVTSKTVAYTNHTVLPEA-LEKWSQSLMWKLLPRHMEIIEEIDKRFVQTI 416 D G+ + T N + P A L Q L +K + II E + ++ Sbjct: 35 DEGVKLHNNVTLQGHTFVGKNTEIFPFAVLGTQPQDLKYKGEYSEL-IIGEDN--LIREF 91 Query: 417 RDTRVDLEDKISSLSILDNNPQKPVVRMANLCVVSSHTV--NGVA-QLHSDI 465 E I I D N V +A+ CV+ SH + NGV H +I Sbjct: 92 CMINPGTEGGIKKTLIGDKNLLMAYVHVAHDCVIGSHCILANGVTLAGHIEI 143 >5NCK-A nrPDB Length = 291 Score = 30.8 bits (68), Expect = 2.7, Method: Composition-based stats. Identities = 10/37 (27%), Positives = 22/37 (59%) Query: 542 KTANKKRLAQYIERVTGVSIDPTSLFDIQVKRIHEYK 578 + A+ L + ++ TG +++ +FD++ K I EY+ Sbjct: 169 QFASTTALIRLVKERTGKTLNGKEIFDLEKKEILEYQ 205 >5OQM-l nrPDB Length = 745 Score = 30.4 bits (67), Expect = 3.0, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 24/71 (33%), Gaps = 8/71 (11%) Query: 761 GPLLDSLEGNTGFGRGDYFLVGYDFPSYMDAQAKVDEAYKDRKGWLKMSILSTAGSGKFS 820 P L+ L D L Y+F + + Y + +LK A GKFS Sbjct: 345 KPRLEKLINEILLKSNDPLLSLYNF---LHKYVLTLQLYMVHREFLK-----LANGGKFS 396 Query: 821 SDRTIAQYAKE 831 I Y + Sbjct: 397 KSNLIHNYDSK 407 >3HR7-A nrPDB Length = 168 Score = 30.0 bits (66), Expect = 4.3, Method: Composition-based stats. Identities = 29/131 (22%), Positives = 45/131 (34%), Gaps = 37/131 (28%) Query: 671 QHISTAGMEASGTSNMKFALNGCLIIGTLD---------GANV-EIREEVGEENFFLF-G 719 QH+ G SG S++ L L + LD G +V EI EE+GE+NF +F Sbjct: 8 QHLVLIGFMGSGKSSLAQELGLALKLEVLDTDMIISERVGLSVREIFEELGEDNFRMFEK 67 Query: 720 ATADQVPRLRKEREDGLFKPDPRFEEAKQFVKSGVFGSYDYGPLLDSLEGNTGFGRGDYF 779 D++ L+ V + + G G F Sbjct: 68 NLIDELKTLKTPH---------------------VISTGG-----GIVMHENLKGLGTTF 101 Query: 780 LVGYDFPSYMD 790 + DF + + Sbjct: 102 YLKMDFETLIK 112 >6NCW-A nrPDB Length = 574 Score = 29.6 bits (65), Expect = 6.0, Method: Composition-based stats. Identities = 20/113 (17%), Positives = 33/113 (29%), Gaps = 6/113 (5%) Query: 179 EEIPEDWLEKFSPWEIVRHDVVFPVRFFGKVQVNPDGSRKWVDGDVVQALAYDVPIPGYG 238 EE+P W E W + D V ++ D+ + G Sbjct: 213 EELPCPWAEC---WSPESPVLYLITAVLRTADGAADDIIDRVGFREIRTEGKDILLNGRK 269 Query: 239 TKNTISLRLWEAKARAEDLDLFQFNEGEYELAAQLHSRAQQICTVLYPGDATE 291 + R + + F+ +++L A I TV YP D Sbjct: 270 LRIKGFCR---HEDHPQFGCALPFSAMQHDLMLIKDLGANSIRTVHYPNDELF 319 >4QHP-A nrPDB Length = 870 Score = 29.3 bits (64), Expect = 7.3, Method: Composition-based stats. Identities = 24/187 (12%), Positives = 47/187 (25%), Gaps = 27/187 (14%) Query: 163 RYRHGLFKQIITKKGQEEIPEDWLEKFSPWEIVRHDVVF---PVRFFGKVQVNPDGSRKW 219 RY L G+ W++ P+ + + G Sbjct: 150 RYPVLLSNGNKIDGGEFSDGRHWVKWEDPFSKPSYLFALVAGDLAVTEDYFTTMSGRNVK 209 Query: 220 VDGDVVQALAYDVPIPGYGTKNTISLRLWEAKARAEDLDLFQF---NEGEY--ELAAQLH 274 ++ +A D P G+ ++ + W+ + DL F G++ Sbjct: 210 IEFYTTEA---DKPKVGFAVESLKNAMKWDETRFGLEYDLDIFMVVAVGDFNMGAMENKG 266 Query: 275 SRAQQICTVL----YPGDATENGKLLRLKQQFFLCSASLQDIISRFHERSTTEGSRKWSE 330 VL D G + ++F + R W + Sbjct: 267 LNIFNTKFVLADSRTATDTDFEGIESVVGHEYF------------HNWTGNRVTCRDWFQ 314 Query: 331 FPSKVAV 337 K + Sbjct: 315 LSLKEGL 321 >6HIV-CJ nrPDB Length = 817 Score = 29.3 bits (64), Expect = 7.9, Method: Composition-based stats. Identities = 18/98 (18%), Positives = 27/98 (27%), Gaps = 15/98 (15%) Query: 184 DWLEKFSPWEIVRHDVVFPVRFFGKVQVNPDGS-RKWVDGDVVQALAY-----DVPIPGY 237 W P ++ + D PV + +D ++ DVP Y Sbjct: 11 YWSRYRMPTQMPKFDGPAPVAAPQSMNSTKTNEFIDPIDDKFPMSIRGPLVRPDVPEDQY 70 Query: 238 ---------GTKNTISLRLWEAKARAEDLDLFQFNEGE 266 T + R W A A FNE + Sbjct: 71 VDSWYICTSMTHHMGDYRPWSASAPPNAFRFRPFNEFD 108 >2YA2-A nrPDB Length = 708 Score = 28.9 bits (63), Expect = 8.5, Method: Composition-based stats. Identities = 40/171 (23%), Positives = 66/171 (38%), Gaps = 34/171 (19%) Query: 499 SPELSDIITKWLKT-DKWITDLDLLTGL-RQFADNEELQSEWASAKTANKKRLAQYIERV 556 P ++ +TK T + +I LD L L + S + + N +RL+ Y Sbjct: 166 DPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVLSYYFVNELKNHERLSDYASSN 225 Query: 557 TGVS--IDPTSLFDIQ----------VKRIHEYK--------RQLMNILGVVYRFKKLKE 596 + + DP + F + KRI E+K R + IL VVY K Sbjct: 226 SNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLINEIHKRGMGAILDVVYNHTA-KV 284 Query: 597 MKPEERKKTV---------PRTVMIGGKAFATYTNAKRIVKLVNDVGDVVN 638 E+ + PRT GG+ T+ KR+ L++ + +V+ Sbjct: 285 DLFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMTKRL--LIDSIKYLVD 333 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.134 0.377 Lambda K H 0.267 0.0406 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 33,908,614 Number of Sequences: 36641 Number of extensions: 1411394 Number of successful extensions: 4010 Number of sequences better than 10.0: 23 Number of HSP's better than 10.0 without gapping: 22 Number of HSP's successfully gapped in prelim test: 25 Number of HSP's that attempted gapping in prelim test: 3865 Number of HSP's gapped (non-prelim): 55 length of query: 841 length of database: 10,336,785 effective HSP length: 105 effective length of query: 736 effective length of database: 6,489,480 effective search space: 4776257280 effective search space used: 4776257280 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 63 (28.9 bits)