BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9R194 (592 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4I6J-A nrPDB 1132 0.0 4K0R-A nrPDB 893 0.0 3FY4-A nrPDB 507 e-144 4JZY-A nrPDB 380 e-106 1OWP-A nrPDB 188 7e-48 1NP7-A nrPDB 187 1e-47 4U63-A nrPDB 183 2e-46 1DNP-A nrPDB 154 1e-37 1U3C-A nrPDB 154 1e-37 2VTB-B nrPDB 137 2e-32 2E0I-A nrPDB 135 5e-32 2J08-A nrPDB 103 1e-22 5O8D-A nrPDB 43 4e-04 3VH2-A nrPDB 31 1.7 3T7E-A nrPDB 30 2.4 5JK7-F nrPDB 29 5.2 1ESX-A nrPDB 28 8.0 >4I6J-A nrPDB Length = 544 Score = 1132 bits (2929), Expect = 0.0, Method: Compositional matrix adjust. Identities = 544/544 (100%), Positives = 544/544 (100%) Query: 1 MAAAAVVAATVPAQSMGADGASSVHWFRKGLRLHDNPALLAAVRGARCVRCVYILDPWFA 60 MAAAAVVAATVPAQSMGADGASSVHWFRKGLRLHDNPALLAAVRGARCVRCVYILDPWFA Sbjct: 1 MAAAAVVAATVPAQSMGADGASSVHWFRKGLRLHDNPALLAAVRGARCVRCVYILDPWFA 60 Query: 61 ASSSVGINRWRFLLQSLEDLDTSLRKLNSRLFVVRGQPADVFPRLFKEWGVTRLTFEYDS 120 ASSSVGINRWRFLLQSLEDLDTSLRKLNSRLFVVRGQPADVFPRLFKEWGVTRLTFEYDS Sbjct: 61 ASSSVGINRWRFLLQSLEDLDTSLRKLNSRLFVVRGQPADVFPRLFKEWGVTRLTFEYDS 120 Query: 121 EPFGKERDAAIMKMAKEAGVEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRMEL 180 EPFGKERDAAIMKMAKEAGVEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRMEL Sbjct: 121 EPFGKERDAAIMKMAKEAGVEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRMEL 180 Query: 181 PKKPAVAVSSQQMESCRAEIQENHDDTYGVPSLEELGFPTEGLGPAVWQGGETEALARLD 240 PKKPAVAVSSQQMESCRAEIQENHDDTYGVPSLEELGFPTEGLGPAVWQGGETEALARLD Sbjct: 181 PKKPAVAVSSQQMESCRAEIQENHDDTYGVPSLEELGFPTEGLGPAVWQGGETEALARLD 240 Query: 241 KHLERKAWVANYERPRMNANSLLASPTGLSPYLRFGCLSCRLFYYRLWDLYKKVKRNSTP 300 KHLERKAWVANYERPRMNANSLLASPTGLSPYLRFGCLSCRLFYYRLWDLYKKVKRNSTP Sbjct: 241 KHLERKAWVANYERPRMNANSLLASPTGLSPYLRFGCLSCRLFYYRLWDLYKKVKRNSTP 300 Query: 301 PLSLFGQLLWREFFYTAATNNPRFDRMEGNPICIQIPWDRNPEALAKWAEGKTGFPWIDA 360 PLSLFGQLLWREFFYTAATNNPRFDRMEGNPICIQIPWDRNPEALAKWAEGKTGFPWIDA Sbjct: 301 PLSLFGQLLWREFFYTAATNNPRFDRMEGNPICIQIPWDRNPEALAKWAEGKTGFPWIDA 360 Query: 361 IMTQLRQEGWIHHLARHAVACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSC 420 IMTQLRQEGWIHHLARHAVACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSC Sbjct: 361 IMTQLRQEGWIHHLARHAVACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSC 420 Query: 421 SAFFQQFFHCYCPVGFGRRTDPSGDYIRRYLPKLKGFPSRYIYEPWNAPESVQKAAKCII 480 SAFFQQFFHCYCPVGFGRRTDPSGDYIRRYLPKLKGFPSRYIYEPWNAPESVQKAAKCII Sbjct: 421 SAFFQQFFHCYCPVGFGRRTDPSGDYIRRYLPKLKGFPSRYIYEPWNAPESVQKAAKCII 480 Query: 481 GVDYPRPIVNHAETSRLNIERMKQIYQQLSRYRGLCLLASVPSCVEDLSHPVAEPGSSQA 540 GVDYPRPIVNHAETSRLNIERMKQIYQQLSRYRGLCLLASVPSCVEDLSHPVAEPGSSQA Sbjct: 481 GVDYPRPIVNHAETSRLNIERMKQIYQQLSRYRGLCLLASVPSCVEDLSHPVAEPGSSQA 540 Query: 541 GSIS 544 GSIS Sbjct: 541 GSIS 544 >4K0R-A nrPDB Length = 617 Score = 893 bits (2307), Expect = 0.0, Method: Compositional matrix adjust. Identities = 405/504 (80%), Positives = 460/504 (91%) Query: 20 GASSVHWFRKGLRLHDNPALLAAVRGARCVRCVYILDPWFAASSSVGINRWRFLLQSLED 79 G ++VHWFRKGLRLHDNPAL ++GA +RCVYILDPWFA SS+VGINRWRFLLQ LED Sbjct: 2 GVNAVHWFRKGLRLHDNPALKECIQGADTIRCVYILDPWFAGSSNVGINRWRFLLQCLED 61 Query: 80 LDTSLRKLNSRLFVVRGQPADVFPRLFKEWGVTRLTFEYDSEPFGKERDAAIMKMAKEAG 139 LD +LRKLNSRLFV+RGQPADVFPRLFKEW +T+L+ EYDSEPFGKERDAAI K+A EAG Sbjct: 62 LDANLRKLNSRLFVIRGQPADVFPRLFKEWNITKLSIEYDSEPFGKERDAAIKKLATEAG 121 Query: 140 VEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRMELPKKPAVAVSSQQMESCRAE 199 VEV+ SHTLYDLD+IIELNG +PPLTYKRFQ L+S+ME + PA ++S + C Sbjct: 122 VEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLVSKMEPLEMPADTITSDVIGKCMTP 181 Query: 200 IQENHDDTYGVPSLEELGFPTEGLGPAVWQGGETEALARLDKHLERKAWVANYERPRMNA 259 + ++HD+ YGVPSLEELGF T+GL AVW GGETEAL RL++HLERKAWVAN+ERPRMNA Sbjct: 182 LSDDHDEKYGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVANFERPRMNA 241 Query: 260 NSLLASPTGLSPYLRFGCLSCRLFYYRLWDLYKKVKRNSTPPLSLFGQLLWREFFYTAAT 319 NSLLASPTGLSPYLRFGCLSCRLFY++L DLYKKVK+NS+PPLSL+GQLLWREFFYTAAT Sbjct: 242 NSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWREFFYTAAT 301 Query: 320 NNPRFDRMEGNPICIQIPWDRNPEALAKWAEGKTGFPWIDAIMTQLRQEGWIHHLARHAV 379 NNPRFD+MEGNPIC+QIPWD+NPEALAKWAEG+TGFPWIDAIMTQLRQEGWIHHLARHAV Sbjct: 302 NNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHAV 361 Query: 380 ACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSCSAFFQQFFHCYCPVGFGRR 439 ACFLTRGDLW+SWE G++VF+ELLLDAD+S+NAGSWMWLSCS+FFQQFFHCYCPVGFGRR Sbjct: 362 ACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQFFHCYCPVGFGRR 421 Query: 440 TDPSGDYIRRYLPKLKGFPSRYIYEPWNAPESVQKAAKCIIGVDYPRPIVNHAETSRLNI 499 TDP+GDYIRRYLP L+GFP++YIY+PWNAPE +QK AKC+IGV+YP+P+VNHAE SRLNI Sbjct: 422 TDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEASRLNI 481 Query: 500 ERMKQIYQQLSRYRGLCLLASVPS 523 ERMKQIYQQLSRYRGL LLASVPS Sbjct: 482 ERMKQIYQQLSRYRGLGLLASVPS 505 >3FY4-A nrPDB Length = 537 Score = 507 bits (1305), Expect = e-144, Method: Compositional matrix adjust. Identities = 251/502 (50%), Positives = 338/502 (67%), Gaps = 19/502 (3%) Query: 18 ADGASSVHWFRKGLRLHDNPALLAAVRGARCVRCVYILDPWFA---------ASSSVGIN 68 A G+ S+ WFRKGLR+HDNPAL A +G+ + V+++DP + SS G+N Sbjct: 2 ATGSGSLIWFRKGLRVHDNPALEYASKGSEFMYPVFVIDPHYMESDPSAFSPGSSRAGVN 61 Query: 69 RWRFLLQSLEDLDTSLRKLNSRLFVVRGQPADVFPRLFKEWGVTRLTFEYDSEPFGKERD 128 R RFLL+SL+DLD+SL+KL SRL V +G+P +V R +EW V RL FEYD++P+ + D Sbjct: 62 RIRFLLESLKDLDSSLKKLGSRLLVFKGEPGEVLVRCLQEWKVKRLCFEYDTDPYYQALD 121 Query: 129 AAIMKMAKEAGVEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRMELPKKPAVAV 188 + A GVEV + SHTL++ IIE NG KPPL+Y+ F +++ +P+ A Sbjct: 122 VKVKDYASSTGVEVFSPVSHTLFNPAHIIEKNGGKPPLSYQSF------LKVAGEPSCAK 175 Query: 189 SSQQME-SCRAEIQE-NHDDTYGVPSLEELGFPTEGLGP-AVWQGGETEALARLDKHLER 245 S M S I + + VPSLEELG+ + ++GGE+EAL RL K + Sbjct: 176 SELVMSYSSLPPIGDIGNLGISEVPSLEELGYKDDEQADWTPFRGGESEALKRLTKSISD 235 Query: 246 KAWVANYERPRMNANSLLA-SPTGLSPYLRFGCLSCRLFYYRLWDLYKKVKRNSTPPLSL 304 KAWVAN+E+P+ + ++ L + T +SPYL+FGCLS R FY L ++YK VK++++PP+SL Sbjct: 236 KAWVANFEKPKGDPSAFLKPATTVMSPYLKFGCLSSRYFYQCLQNIYKDVKKHTSPPVSL 295 Query: 305 FGQLLWREFFYTAATNNPRFDRMEGNPICIQIPWDRNPEALAKWAEGKTGFPWIDAIMTQ 364 GQLLWREFFYT A P FD+M+GN IC QIPW+ + LA W +GKTG+PWIDAIM Q Sbjct: 296 LGQLLWREFFYTTAFGTPNFDKMKGNRICKQIPWNEDHAMLAAWRDGKTGYPWIDAIMVQ 355 Query: 365 LRQEGWIHHLARHAVACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSCSAFF 424 L + GW+HHLARH VACFLTRGDL++ WE G VF+ LL+D+D+++N G+WMWLSCS+FF Sbjct: 356 LLKWGWMHHLARHCVACFLTRGDLFIHWEQGRDVFERLLIDSDWAINNGNWMWLSCSSFF 415 Query: 425 QQFFHCYCPVGFGRRTDPSGDYIRRYLPKLKGFPSRYIYEPWNAPESVQKAAKCIIGVDY 484 QF Y P+ FG++ DP G YIR +LP LK P +YIYEPW AP SVQ A CI+G DY Sbjct: 416 YQFNRIYSPISFGKKYDPDGKYIRHFLPVLKDMPKQYIYEPWTAPLSVQTKANCIVGKDY 475 Query: 485 PRPIVNHAETSRLNIERMKQIY 506 P+P+V H S+ +M + Y Sbjct: 476 PKPMVLHDSASKECKRKMGEAY 497 >4JZY-A nrPDB Length = 536 Score = 380 bits (976), Expect = e-106, Method: Compositional matrix adjust. Identities = 216/522 (41%), Positives = 301/522 (57%), Gaps = 37/522 (7%) Query: 15 SMGADGASSVHWFRKGLRLHDNPALLAAV----RGARCVRCVYILDPWFAASSSVGINRW 70 +M GA+ + WFR GLRLHDNPALLAA+ +G + V+I D A + +VG NR Sbjct: 1 AMATRGANVI-WFRHGLRLHDNPALLAALADKDQGIALIP-VFIFDGESAGTKNVGYNRM 58 Query: 71 RFLLQSLEDLDTSLRKLNS---RLFVVRGQPADVFPRLFKEWGVTRLTFEYDSEPFGKER 127 RFLL SL+D+D L+ RL V G+PA +F RL ++ + R+ E D EP ER Sbjct: 59 RFLLDSLQDIDDQLQAATDGRGRLLVFEGEPAYIFRRLHEQVRLHRICIEQDCEPIWNER 118 Query: 128 DAAIMKMAKEAGVEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRMELPKKPAVA 187 D +I + +E ++ V + SHTL+D +IE NG PPLTY+ F + + LP +P Sbjct: 119 DESIRSLCRELNIDFVEKVSHTLWDPQLVIETNGGIPPLTYQMFLHTVQIIGLPPRPTAD 178 Query: 188 VSSQQM-------ESCRA-EIQEN-----HDDTYGVPSLEELGFPTEGLGPAVWQGGETE 234 + E CR+ ++ E H + YG + +GF L W+GGET+ Sbjct: 179 ARLEDATFVELDPEFCRSLKLFEQLPTPEHFNVYG----DNMGF----LAKINWRGGETQ 230 Query: 235 ALARLDKHL--ERKAWVANYERPRMNANSLLASPTGLSPYLRFGCLSCRLFYYRLWDLYK 292 AL LD+ L E+ A+ + P ++ SP +S +LRFGCLS R FY+ + DL+K Sbjct: 231 ALLLLDERLKVEQHAFERGFYLPNQALPNIHDSPKSMSAHLRFGCLSVRRFYWSVHDLFK 290 Query: 293 KVKR--NSTPPLSLFGQLLWREFFYTAATNNPRFDRMEGNPICIQIPWDR-NPEALAKWA 349 V+ T + GQL+WRE+FYT + NNP +DRMEGN IC+ IPW + N L W Sbjct: 291 NVQLGVQMTGGAHITGQLIWREYFYTMSVNNPNYDRMEGNDICLSIPWAKPNENLLQSWR 350 Query: 350 EGKTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWVSWESGVRVFDELLLDADFS 409 G+TGFP ID M QL EGW+HH R+ VA FLTRG LW SWE G++ F + LLDAD+S Sbjct: 351 LGQTGFPLIDGAMRQLLAEGWLHHTLRNTVATFLTRGGLWQSWEHGLQHFLKYLLDADWS 410 Query: 410 VNAGSWMWLSCSAFFQQFFHCY--CPVGFGRRTDPSGDYIRRYLPKLKGFPSRYIYEPWN 467 V AG+WMW+S SAF + CPV +R DP G YI++Y+P+L P +++EPW Sbjct: 411 VCAGNWMWVSSSAFERLLDSSLVTCPVALAKRLDPDGTYIKQYVPELMNVPKEFVHEPWR 470 Query: 468 APESVQKAAKCIIGVDYPRPIVNHAETSRLNIERMKQIYQQL 509 Q+ +C+IGV YP I++ + + N+ MK + L Sbjct: 471 MSAEQQEQYECLIGVHYPERIIDLSMAVKRNMLAMKSLRNSL 512 >1OWP-A nrPDB Length = 484 Score = 188 bits (477), Expect = 7e-48, Method: Compositional matrix adjust. Identities = 144/501 (28%), Positives = 240/501 (47%), Gaps = 42/501 (8%) Query: 20 GASSVHWFRKGLRLHDNPALLAAVRGARCVRCVYILDPWFAASSSVGINRWRFLLQSLED 79 A + W R+ LRL DN L AA + + ++ LDP S+ + R +L L++ Sbjct: 2 AAPILFWHRRDLRLSDNIGLAAARAQSAQLIGLFCLDPQILQSADMAPARVAYLQGCLQE 61 Query: 80 LDTSLRKLNSRLFVVRGQPADVFPRLFKEWGVTRLTFEYDSEPFGKERDAAIMKMAKEAG 139 L ++ SRL +++G P + P+L ++ + + D EP+G++RD + K AG Sbjct: 62 LQQRYQQAGSRLLLLQGDPQHLIPQLAQQLQAEAVYWNQDIEPYGRDRDGQVAAALKTAG 121 Query: 140 VEVVTENSHTLYDLDRIIELNGQKPPLT-----YKRFQALISRMELPKKPAVAVSSQQME 194 + V L+ D+I L+G P + +K +QA PK VA ++ ++ Sbjct: 122 IRAVQLWDQLLHSPDQI--LSGSGNPYSVYGPFWKNWQA------QPKPTPVATPTELVD 173 Query: 195 SCRAEIQENHDDTYG-VPSLEELGFPTEGLGPAVWQGGETEALARLDKHLERKAWVANYE 253 ++ +P+L++LGF +G P + GET A+ARL + +R +A+Y+ Sbjct: 174 LSPEQLTAIAPLLLSELPTLKQLGFDWDGGFPV--EPGETAAIARLQEFCDRA--IADYD 229 Query: 254 RPRMNANSLLASPTGLSPYLRFGCLSCRLFYYRLWDLYKKVK----RNSTPPLSLFGQ-L 308 P+ N + A +GLSP L+FG + R + + + RNS + ++ Q L Sbjct: 230 -PQRNFPA-EAGTSGLSPALKFGAIGIRQAWQAASAAHALSRSDEARNS---IRVWQQEL 284 Query: 309 LWREFFYTAATNNPRFDRMEGNPICIQIPWDRNPEALAKWAEGKTGFPWIDAIMTQLRQE 368 WREF+ A + P + Q PW+ W + +TG+P +DA M QL + Sbjct: 285 AWREFYQHALYHFPSLADGPYRSLWQQFPWENREALFTAWTQAQTGYPIVDAAMRQLTET 344 Query: 369 GWIHHLARHAVACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSCSAFFQQFF 428 GW+H+ R VA FLT+ DL + W G + F + L+D D + N G W W + S + Sbjct: 345 GWMHNRCRMIVASFLTK-DLIIDWRRGEQFFMQHLVDGDLAANNGGWQWSASSGMDPKPL 403 Query: 429 HCYCPVGFGRRTDPSGDYIRRYLPKLKGFPSRYIYEPWNAPESVQKAAKCIIGVDYPRPI 488 + P ++ D + YI+R+LP+L R+++ + + I YP PI Sbjct: 404 RIFNPASQAKKFDATATYIKRWLPEL-----RHVH----PKDLISGEITPIERRGYPAPI 454 Query: 489 VNHAETSRLNIERMKQIYQQL 509 VNH L ++ K +Y QL Sbjct: 455 VNH----NLRQKQFKALYNQL 471 >1NP7-A nrPDB Length = 489 Score = 187 bits (474), Expect = 1e-47, Method: Compositional matrix adjust. Identities = 144/493 (29%), Positives = 233/493 (47%), Gaps = 28/493 (5%) Query: 26 WFRKGLRLHDNPALLAAVRGARCVRCVYILDPWFAASSSVGINR---WR--FLLQSLEDL 80 WFR LRLHD+ L A++ + VY DP A + G + WR FL QS+++L Sbjct: 11 WFRNDLRLHDHEPLHRALKSGLAITAVYCYDPRQFAQTHQGFAKTGPWRSNFLQQSVQNL 70 Query: 81 DTSLRKLNSRLFVVRGQPADVFPRLFKEWGVTRLTFEYDSEPFGKERDAA--IMKMAKEA 138 SL+K+ ++L V G P V P++ K+ + T Y E +E D ++K Sbjct: 71 AESLQKVGNKLLVTTGLPEQVIPQIAKQ--INAKTIYYHREVTQEELDVERNLVKQLTIL 128 Query: 139 GVEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRMELPKKPAVAVSSQQMESCRA 198 G+E TL + + + Q P + +F+ I + ++ +P SQ + S Sbjct: 129 GIEAKGYWGSTLCHPEDL-PFSIQDLPDLFTKFRKDIEKKKISIRPCFFAPSQLLPSPNI 187 Query: 199 EIQENHDDTYGVPSLEELGFPTEGLGPAVWQGGETEALARLDKHLERKAWVANYERPRMN 258 +++ P ++ F + +QGGET LARL + + +Y+ R Sbjct: 188 KLELTAPPPEFFP---QINFDHRSV--LAFQGGETAGLARLQDYFWHGDRLKDYKETR-- 240 Query: 259 ANSLLAS--PTGLSPYLRFGCLSCRLFYYRLWDLYKKVKRNSTPPLSLFGQLLWREFFYT 316 N ++ + + SP+L GCLS R Y + Y++ + ++ L +LLWR+FF Sbjct: 241 -NGMVGADYSSKFSPWLALGCLSPRFIYQEV-KRYEQERVSNDSTHWLIFELLWRDFFRF 298 Query: 317 AATN--NPRFDRMEGNPICIQIPWDRNPEALAKWAEGKTGFPWIDAIMTQLRQEGWIHHL 374 A N F+R G + PW + W G+TG+P +DA M +L G++ + Sbjct: 299 VAQKYGNKLFNR--GGLLNKNFPWQEDQVRFELWRSGQTGYPLVDANMRELNLTGFMSNR 356 Query: 375 ARHAVACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSCSAFFQQFFHCYCPV 434 R VA FL + +L + W G F+ L+D D N G+W + + + F + Sbjct: 357 GRQNVASFLCK-NLGIDWRWGAEWFESCLIDYDVCSNWGNWNYTAGIGNDARDFRYFNIP 415 Query: 435 GFGRRTDPSGDYIRRYLPKLKGFPSRYIYEPWNAPESVQKAAKCIIGVDYPRPIVNHAET 494 ++ DP G Y+R +LP+LK P I++PW + QK +GVDYPRP VN ++ Sbjct: 416 KQSQQYDPQGTYLRHWLPELKNLPGDKIHQPWLLSATEQKQWGVQLGVDYPRPCVNFHQS 475 Query: 495 --SRLNIERMKQI 505 +R IE+M I Sbjct: 476 VEARRKIEQMGVI 488 >4U63-A nrPDB Length = 498 Score = 183 bits (465), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 143/477 (29%), Positives = 220/477 (46%), Gaps = 23/477 (4%) Query: 21 ASSVHWFRKGLRLHDNPALLAAVRGARCVRCVYILDPWFAASSSVGINRWRFLLQSLEDL 80 A + WFRK LRL DN ALLAAV V VYI + +A G W +L SL L Sbjct: 25 APVIVWFRKDLRLSDNLALLAAVEHGGPVIPVYIREK--SAGPLGGAQEW-WLHHSLAAL 81 Query: 81 DTSLRKLNSRLFVVRGQPADVFPRLFKEWGVTRLTFEYDSEPFGKERDAAIMKMAKEAGV 140 +SL K RL + G + L E G + + +P G D A+ + ++ G+ Sbjct: 82 SSSLEKAGGRLVLASGDAERILRDLISETGADTVVWNRRYDPTGMATDKALKQKLRDDGL 141 Query: 141 EVVTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRMELPKKPAVAVSSQQMESCRAEI 200 V + + L++ R+ +G P Y F + + P PA S + Sbjct: 142 TVRSFSGQLLHEPSRLQTKSGG-PYRVYTPFWRALEGSDEPHAPADPPKSLTAPKVWPK- 199 Query: 201 QENHDDTYGVPSLEELGFPTEGLGPAVWQGGETEALARLDKHLER--KAWVANYERPRMN 258 E + +P+ + +W GET AL +LD ++ K + + P Sbjct: 200 SEKLSNWKLLPTKPDWAKDFSD----IWTPGETGALDKLDDFIDGALKGYEEGRDFPAKP 255 Query: 259 ANSLLASPTGLSPYLRFGCLSCRLFYYRLWDLYKKVKRNSTPPLSLF-GQLLWREFFYTA 317 A SLL SP+L G +S ++ L + + N +S F +++WREF Y Sbjct: 256 ATSLL------SPHLAAGEISPAAVWHATKGLSRHIASND---ISRFRKEIVWREFCYHL 306 Query: 318 ATNNPRFDRMEGNPICIQIPWDRNPEALAKWAEGKTGFPWIDAIMTQLRQEGWIHHLARH 377 + P N W + ++ W G TG+P +DA M QL Q G +H+ R Sbjct: 307 LFHFPELGEKNWNDSFDAFSWRDDEKSFKAWTRGMTGYPIVDAGMRQLWQHGTMHNRVRM 366 Query: 378 AVACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSCS-AFFQQFFHCYCPVGF 436 VA FL + L + W G + F + L+DAD + NA +W W++ S A FF + P+ Sbjct: 367 IVASFLIK-HLLIDWRKGEKWFRDTLVDADPASNAANWQWVAGSGADASPFFRIFNPILQ 425 Query: 437 GRRTDPSGDYIRRYLPKLKGFPSRYIYEPWNAPESVQKAAKCIIGVDYPRPIVNHAE 493 G + D GDY+RR++P+L+ +YI++P+ AP+ K A +G YP PIV+H + Sbjct: 426 GEKFDGDGDYVRRFVPELEKLERKYIHKPFEAPKDALKKAGVELGKTYPLPIVDHGK 482 >1DNP-A nrPDB Length = 471 Score = 154 bits (389), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 133/478 (27%), Positives = 207/478 (43%), Gaps = 38/478 (7%) Query: 26 WFRKGLRLHDNPALLAAVRGARC-VRCVYILDPWFAASSSVGINRWRFLLQSLEDLDTSL 84 WFR+ LRLHDN AL AA R + V +YI P A+ ++ + + L L +L Sbjct: 6 WFRQDLRLHDNLALAAACRNSSARVLALYIATPRQWATHNMSPRQAELINAQLNGLQIAL 65 Query: 85 RKLNSRLFVVRGQ----PADVFPRLFKEWGVTRLTFEYDSEPFGKERDAAIMKMAKEAGV 140 + L ++ ++ E VT L + Y E + RD + + + Sbjct: 66 AEKGIPLLFREVDDFVASVEIVKQVCAENSVTHLFYNYQYEVNERARDVEVERALR---- 121 Query: 141 EVVTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRMELPKKPA-VAVSSQQMESCRAE 199 VV E +D I+ PP + ++ P K A + + M C A Sbjct: 122 NVVCEG----FDDSVIL------PPGAVMTGNHEMYKVFTPFKNAWLKRLREGMPECVAA 171 Query: 200 IQENHDDTYGVPSLEELGFPTEGLGPAVWQGGETEALARLDKHLERKAWVANYERPRMNA 259 + + L +P + A + E A+A+L + + A YE+ R Sbjct: 172 PKVRSSGSIEPSPSITLNYPRQSFDTAHFPVEEKAAIAQLRQFCQNGA--GEYEQQR--D 227 Query: 260 NSLLASPTGLSPYLRFGCLSCRLFYYRLWDLYKKVKRNSTPPLSLFGQLLWREFFYTAAT 319 + + LS L G LS R +RL + + L +L+WREF+ T Sbjct: 228 FPAVEGTSRLSASLATGGLSPRQCLHRLLAEQPQALDGGAGSVWL-NELIWREFYRHLIT 286 Query: 320 NNPRFDRMEGNPICI---QIPWDRNPEALAKWAEGKTGFPWIDAIMTQLRQEGWIHHLAR 376 +P + P ++ W NP L W EGKTG+P +DA M QL GW+H+ R Sbjct: 287 YHPSL--CKHRPFIAWTDRVQWQSNPAHLQAWQEGKTGYPIVDAAMRQLNSTGWMHNRLR 344 Query: 377 HAVACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSCSAFFQQ-FFHCYCPVG 435 A FL + DL + W G R F L+D D + N G W W + + +F + P Sbjct: 345 MITASFLVK-DLLIDWREGERYFMSQLIDGDLAANNGGWQWAASTGTDAAPYFRIFNPTT 403 Query: 436 FGRRTDPSGDYIRRYLPKLKGFPSRYIYEPWNAPESVQKAAKCIIGVDYPRPIVNHAE 493 G + D G++IR++LP+L+ P + ++EPW + A K + +DYP+PIV H E Sbjct: 404 QGEKFDHEGEFIRQWLPELRDVPGKVVHEPW------KWAQKAGVTLDYPQPIVEHKE 455 >1U3C-A nrPDB Length = 509 Score = 154 bits (389), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 140/501 (27%), Positives = 227/501 (45%), Gaps = 39/501 (7%) Query: 24 VHWFRKGLRLHDNPALLAAVRGARCVRCVYILDPWFAASSSVG-INRWRFLLQSLEDLDT 82 + WFR+ LR+ DNPAL AAVR + +++ P G ++RW +L SL LD+ Sbjct: 15 IVWFRRDLRVEDNPALAAAVRAGPVI-ALFVWAPEEEGHYHPGRVSRW-WLKNSLAQLDS 72 Query: 83 SLRKLNSRLFVVRGQPADV-FPRLFKEWGVTRLTFEYDSEPFGKERDAAIMKMAKEAGVE 141 SLR L + L R + + K G +++ F + +P RD + G+ Sbjct: 73 SLRSLGTCLITKRSTDSVASLLDVVKSTGASQIFFNHLYDPLSLVRDHRAKDVLTAQGIA 132 Query: 142 VVTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRM-------ELPKKPAVAVSSQQME 194 V + N+ LY+ + + G+ + F A R E P P + S + Sbjct: 133 VRSFNADLLYEPWEVTDELGRP----FSMFAAFWERCLSMPYDPESPLLPPKKIISGDVS 188 Query: 195 SCRAEIQENHDDTYGVPSLEELGFPTEGLGPAVWQGGETEALARLDKHLERKAWVANYER 254 C A+ DD+ E G + L W G + L + + Y + Sbjct: 189 KCVADPLVFEDDS-------EKG--SNALLARAWSPGWSNGDKALTTFINGP--LLEYSK 237 Query: 255 PRMNANSLLASPTGLSPYLRFGCLSCRLFYYRLWDLYKKV------KRNSTPPLSLFGQL 308 R A+S A+ + LSP+L FG +S R ++ + K+V ++LF + Sbjct: 238 NRRKADS--ATTSFLSPHLHFGEVSVRKVFHLV--RIKQVAWANEGNEAGEESVNLFLKS 293 Query: 309 L-WREFFYTAATNNPRFDRMEGNPICIQIPWDRNPEALAKWAEGKTGFPWIDAIMTQLRQ 367 + RE+ + N+P PW + W +G+TG+P +DA M +L Sbjct: 294 IGLREYSRYISFNHPYSHERPLLGHLKFFPWAVDENYFKAWRQGRTGYPLVDAGMRELWA 353 Query: 368 EGWIHHLARHAVACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSCSA-FFQQ 426 GW+H R V+ L + W G++ F + LLDAD +A W +++ + ++ Sbjct: 354 TGWLHDRIRVVVSS-FFVKVLQLPWRWGMKYFWDTLLDADLESDALGWQYITGTLPDSRE 412 Query: 427 FFHCYCPVGFGRRTDPSGDYIRRYLPKLKGFPSRYIYEPWNAPESVQKAAKCIIGVDYPR 486 F P G + DP+G+Y+RR+LP+L P+ +I+ PWNAPESV +AA +G +YP Sbjct: 413 FDRIDNPQFEGYKFDPNGEYVRRWLPELSRLPTDWIHHPWNAPESVLQAAGIELGSNYPL 472 Query: 487 PIVNHAETSRLNIERMKQIYQ 507 PIV E E + Q++Q Sbjct: 473 PIVGLDEAKARLHEALSQMWQ 493 >2VTB-B nrPDB Length = 525 Score = 137 bits (344), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 124/453 (27%), Positives = 205/453 (45%), Gaps = 37/453 (8%) Query: 23 SVHWFRKGLRLHDNPALLAAVRGARCVRCVYILDP------WFAASSSVGINRWRFLLQS 76 ++ WFR LR+ DN AL A + + VY LDP F G R FL++ Sbjct: 43 TILWFRNDLRVLDNDALYKAWSSSDTILPVYCLDPRLFHTTHFFNFPKTGALRGGFLMEC 102 Query: 77 LEDLDTSLRKLNSRLFVVRGQPADVFPRLFKEWGVTRLTFEYD---SEPFGKER--DAAI 131 L DL +L K L + G+P ++ P L K++G R F + SE ER + + Sbjct: 103 LVDLRKNLMKRGLNLLIRSGKPEEILPSLAKDFGA-RTVFAHKETCSEEVDVERLVNQGL 161 Query: 132 MKMAKEAGVEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQALI-SRMELPKKPAVAVSS 190 ++ +E++ T+Y D + + P Y +F+ + ++ + + +S Sbjct: 162 KRVGNSTKLELIW--GSTMYHKDDL-PFDVFDLPDVYTQFRKSVEAKCSIRSSTRIPLSL 218 Query: 191 QQMESCRAEIQENHDDTYGVPSLEELGF-PTEGLGPAVWQGGETEALARLDKHLERKAWV 249 S DD VP+LE+LG P E + GGE+ + R+ ++ +K + Sbjct: 219 GPTPSV--------DDWGDVPTLEKLGVEPQEVTRGMRFVGGESAGVGRVFEYFWKKDLL 270 Query: 250 ANYERPRMNANSLLA--SPTGLSPYLRFGCLSCRLFYYRLWDLYKKVKRNSTPPLSLFGQ 307 Y+ R N +L T SP+L FGC+S R Y + K+ N++ LF + Sbjct: 271 KVYKETR---NGMLGPDYSTKFSPWLAFGCISPRFIYEEVQRYEKERVANNSTYWVLF-E 326 Query: 308 LLWREFF--YTAATNNPRFDRMEGNPICIQIPWDRNPEALAKWAEGKTGFPWIDAIMTQL 365 L+WR++F + N F G P + W ++ + W + KTG+P IDA M +L Sbjct: 327 LIWRDYFRFLSIKCGNSLFHL--GGPRNVNGKWSQDQKLFESWRDAKTGYPLIDANMKEL 384 Query: 366 RQEGWIHHLARHAVACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSCSAFFQ 425 G++ + R V FL R D+ + W G F+ LLD D N G+W + + + Sbjct: 385 STTGFMSNRGRQIVCSFLVR-DMGLDWRMGAEWFETCLLDYDPCSNYGNWTYGAGVNDPR 443 Query: 426 QFFHCYCPVGFGRRTDPSGDYIRRYLPKLKGFP 458 + + P + DP G+Y+ +L +L+ P Sbjct: 444 EDRYFSIPKQ-AQNYDPEGEYVAFWLQQLRRLP 475 >2E0I-A nrPDB Length = 440 Score = 135 bits (340), Expect = 5e-32, Method: Compositional matrix adjust. Identities = 129/478 (26%), Positives = 200/478 (41%), Gaps = 79/478 (16%) Query: 27 FRKGLRLHDNPALLAAVRGARCVRCVYILDPW------FAASSSVGINRWRFLLQSLEDL 80 FR+ LRL DN L A+ V V+I DP + + +V F++ SL +L Sbjct: 7 FRRDLRLEDNTGLNYALSECDRVIPVFIADPRQLINNPYKSEFAVS-----FMINSLLEL 61 Query: 81 DTSLRKLNSRLFVVRGQPADVFPRLFKEWGVTRLTFEYDSEPFGKERDAAIMKMAKEAGV 140 D LRK SRL V G+ V R F + V + D PF RD I K+ +E G+ Sbjct: 62 DDELRKKGSRLNVFFGEAEKVVSRFFNK--VDAIYVNEDYTPFSISRDEKIRKVCEENGI 119 Query: 141 EVVTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRMELPKKPAVAVSSQQMESCRAEI 200 E + L K ++ F + + + V V + ++ Sbjct: 120 EFKAYEDYLL----------TPKSLFHHRNFTSFYNEV-----SKVKVREPETMEGSFDV 164 Query: 201 QENHDDTYGVPSLEELGFPTEGLGPAVWQGGETEALARLDKHLERKAWVANYERPRMNAN 260 ++ + + + +++ P +++GG E L L ++++ + + P N N Sbjct: 165 TDSSMNVDFLLTFKKIESP-------LFRGGRREGLYLLHRNVDFR----RRDYPAENNN 213 Query: 261 SLLASPTGLSPYLRFGCLSCRLFYYRLWDLYKKVKRNSTPPLSLFGQLLWREFFYTAATN 320 LSP+L+FG +S R YY +K K +L WR+FF A Sbjct: 214 ------YRLSPHLKFGTISMREAYYT-----QKGKE------EFVRELYWRDFFTLLAYY 256 Query: 321 NPR-----FDRMEGNPICIQIPWDRNPEALAKWAEGKTGFPWIDAIMTQLRQEGWIHHLA 375 NP + R N I W+ N W EG+TG+P IDA M L G+I+ Sbjct: 257 NPHVFGHCYRREYDN-----ISWENNESYFEAWKEGRTGYPIIDAGMRMLNSTGYINGRV 311 Query: 376 RHAVACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSCSAFFQQFFHCYCPVG 435 R VA FL + L+V W G R F L+D D ++N G+W W++ + F + P Sbjct: 312 RMLVAFFLVKV-LFVDWRWGERYFATKLVDYDPAINNGNWQWIASTG-VDYMFRVFNPWK 369 Query: 436 FGRRTDPSGDYIRRYLPKLKGFPSRYIYEPWNAPESVQKAAKCIIGVDYPRPIVNHAE 493 + DP +I+ ++ +LK P P + K + YP PIVN E Sbjct: 370 QQEKFDPEAKFIKEWVEELKDVP----------PSIIHSIYKTKVP-GYPSPIVNWLE 416 >2J08-A nrPDB Length = 420 Score = 103 bits (258), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 119/435 (27%), Positives = 168/435 (38%), Gaps = 50/435 (11%) Query: 26 WFRKGLRLHDNPALLAAVRGARCVRCVYILDPWFAASSSVGINRWRFLLQSLEDLDTSLR 85 W R LRLHD+PALL A+ V V +LDP + R + L+++ L + R Sbjct: 7 WHRGDLRLHDHPALLEALARGPVVGLV-VLDP---NNLKTTPRRRAWFLENVRALREAYR 62 Query: 86 KLNSRLFVVRGQPADVFPRLFKEWGVTRLTFEYDSEPFGKERDAAIMKMAKEAGVEVVTE 145 L+V+ G P+ K +AA AK V Sbjct: 63 ARGGALWVLEGL------------------------PWEKVPEAARRLKAKA----VYAL 94 Query: 146 NSHTLYDLDRIIELNGQKPPLTYKRFQALISRMELPKKPAVAVSSQQMESCRAEIQENHD 205 SHT Y R + P + + +LP+ A V + R Sbjct: 95 TSHTPYGRYRDGRVREALPVPLHLLPAPHLLPPDLPR--AYRVYTPFSRLYRGAAPPLPP 152 Query: 206 DTYGVPSLEELGFPTEGLGPAVWQGGETEALARLDKHLERKAWVANYERPRMNANSLLAS 265 EE P E G + + GE ALA L LE K ER R++ Sbjct: 153 PEALPKGPEEGEIPREDPGLPLPEPGEEAALAGLRAFLEAKLPRYAEERDRLDGEG---- 208 Query: 266 PTGLSPYLRFGCLSCRLFYYRLWDLYKKVKRNSTPPLSLFGQLLWREFFYTAATNNPRFD 325 + LSPY G LS RL ++ +R +LLWR+F Y + P Sbjct: 209 GSRLSPYFALGVLSPRL------AAWEAERRGGEGARKWVAELLWRDFSYHLLYHFPWMA 262 Query: 326 RMEGNPICIQIPWDRNPEALAKWAEGKTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTR 385 +P PW + W EGKTG P +DA M +L G++ + AR A F + Sbjct: 263 ERPLDPRFQAFPWQEDEALFQAWYEGKTGVPLVDAAMRELHATGFLSNRARMNAAQFAVK 322 Query: 386 GDLWVSWESGVRVFDELLLDADFSVNAGSWMW---LSCSAFFQQFFHCYCPVGFGRRTDP 442 L + W+ F LLLD D +VN W W L A +F + PV G R DP Sbjct: 323 -HLLLPWKRCEEAFRHLLLDGDRAVNLQGWQWAGGLGVDA--APYFRVFNPVLQGERHDP 379 Query: 443 SGDYIRRYLPKLKGF 457 G +++R+ P+ + Sbjct: 380 EGRWLKRWAPEYPSY 394 >5O8D-A nrPDB Length = 484 Score = 43.1 bits (100), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 29/99 (29%), Positives = 48/99 (48%), Gaps = 7/99 (7%) Query: 24 VHWFRKGLRLHDNPALL---AAVRGARC-VRCVYILDPWFAASSSVGINRWRFLLQSLED 79 V+W + R DN ALL A + A V V+ L F + GI ++ F+L+ L++ Sbjct: 42 VYWMSRDQRAEDNWALLFSRAIAKEANVPVVVVFCLTDEFLEA---GIRQYEFMLKGLQE 98 Query: 80 LDTSLRKLNSRLFVVRGQPADVFPRLFKEWGVTRLTFEY 118 L+ SL + F +RG P + R K++ L ++ Sbjct: 99 LEVSLSRKKIPSFFLRGDPGEKISRFVKDYNAGTLVTDF 137 Score = 29.6 bits (65), Expect = 3.9, Method: Compositional matrix adjust. Identities = 31/118 (26%), Positives = 49/118 (41%), Gaps = 12/118 (10%) Query: 267 TGLSPYLRFGCLSCRLFYYRLWDLYKKVKRNSTPPLSLFGQ-LLWREFFYTAATNNPRFD 325 + LSPYL FG +S + R+ +K + N + + L+W+E NP +D Sbjct: 285 SNLSPYLHFGQISSQ----RVVLEVEKAESNPGSKKAFLDEILIWKEISDNFCYYNPGYD 340 Query: 326 RMEGNPICIQ--IPWDRNPE-----ALAKWAEGKTGFPWIDAIMTQLRQEGWIHHLAR 376 E P + + RN L ++ GKT P +A +L G +H R Sbjct: 341 GFESFPSWAKESLNAHRNDVRSHIFTLEEFEAGKTHDPLWNASQMELLSTGKMHGYTR 398 >3VH2-A nrPDB Length = 616 Score = 30.8 bits (68), Expect = 1.7, Method: Compositional matrix adjust. Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 8/74 (10%) Query: 47 RCVRCVYILDPWFAASSSVGIN----RWRFLLQSLEDLDTSLRKLNSRLFVVRGQPADVF 102 R V +LDP A SV +N +WR L DL+ + K L + G Sbjct: 287 RVVDLSSLLDPLKIADQSVDLNLKLMKWRIL----PDLNLDIIKNTKVLLLGAGTLGCYV 342 Query: 103 PRLFKEWGVTRLTF 116 R WGV ++TF Sbjct: 343 SRALIAWGVRKITF 356 >3T7E-A nrPDB Length = 344 Score = 30.4 bits (67), Expect = 2.4, Method: Compositional matrix adjust. Identities = 21/67 (31%), Positives = 29/67 (43%), Gaps = 8/67 (11%) Query: 54 ILDPWFAASSSVGIN----RWRFLLQSLEDLDTSLRKLNSRLFVVRGQPADVFPRLFKEW 109 +LDP A SV +N +WR L DL+ + K L + G R W Sbjct: 5 LLDPLKIADQSVDLNLKLMKWRIL----PDLNLDIIKNTKVLLLGAGTLGCYVSRALIAW 60 Query: 110 GVTRLTF 116 GV ++TF Sbjct: 61 GVRKITF 67 >5JK7-F nrPDB Length = 96 Score = 29.3 bits (64), Expect = 5.2, Method: Compositional matrix adjust. Identities = 12/35 (34%), Positives = 20/35 (57%), Gaps = 3/35 (8%) Query: 370 WIHHLARHAVACFLTRGDLWVSWESGVRVFDELLL 404 W+H+L +H + T GD W E+ +R+ +LL Sbjct: 38 WLHNLGQH---IYETYGDTWAGVEAIIRILQQLLF 69 >1ESX-A nrPDB Length = 96 Score = 28.5 bits (62), Expect = 8.0, Method: Composition-based stats. Identities = 12/35 (34%), Positives = 19/35 (54%), Gaps = 3/35 (8%) Query: 370 WIHHLARHAVACFLTRGDLWVSWESGVRVFDELLL 404 W+H L +H + T GD W E+ +R+ +LL Sbjct: 38 WLHSLGQH---IYETYGDTWTGVEALIRILQQLLF 69 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4I6J-A nrPDB 808 0.0 4K0R-A nrPDB 726 0.0 3FY4-A nrPDB 614 e-176 4JZY-A nrPDB 564 e-161 1NP7-A nrPDB 543 e-155 4U63-A nrPDB 519 e-147 1OWP-A nrPDB 493 e-140 1DNP-A nrPDB 484 e-137 1U3C-A nrPDB 475 e-134 2VTB-B nrPDB 459 e-129 2E0I-A nrPDB 449 e-126 2J08-A nrPDB 374 e-104 5O8D-A nrPDB 155 6e-38 Sequences not found previously or not previously below threshold: 3UMV-A nrPDB 78 1e-14 4Z5P-A nrPDB 34 0.15 3E6I-A nrPDB 34 0.25 5GAM-A nrPDB 34 0.27 2X0P-A nrPDB 33 0.40 6D97-A nrPDB 32 0.55 5M99-B nrPDB 32 0.55 3LGB-A nrPDB 31 1.2 3QR1-A nrPDB 30 2.6 1KB0-A nrPDB 30 3.3 4YZZ-A nrPDB 30 3.7 4NUR-A nrPDB 29 5.6 >4I6J-A nrPDB Length = 544 Score = 808 bits (2087), Expect = 0.0, Method: Composition-based stats. Identities = 544/544 (100%), Positives = 544/544 (100%) Query: 1 MAAAAVVAATVPAQSMGADGASSVHWFRKGLRLHDNPALLAAVRGARCVRCVYILDPWFA 60 MAAAAVVAATVPAQSMGADGASSVHWFRKGLRLHDNPALLAAVRGARCVRCVYILDPWFA Sbjct: 1 MAAAAVVAATVPAQSMGADGASSVHWFRKGLRLHDNPALLAAVRGARCVRCVYILDPWFA 60 Query: 61 ASSSVGINRWRFLLQSLEDLDTSLRKLNSRLFVVRGQPADVFPRLFKEWGVTRLTFEYDS 120 ASSSVGINRWRFLLQSLEDLDTSLRKLNSRLFVVRGQPADVFPRLFKEWGVTRLTFEYDS Sbjct: 61 ASSSVGINRWRFLLQSLEDLDTSLRKLNSRLFVVRGQPADVFPRLFKEWGVTRLTFEYDS 120 Query: 121 EPFGKERDAAIMKMAKEAGVEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRMEL 180 EPFGKERDAAIMKMAKEAGVEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRMEL Sbjct: 121 EPFGKERDAAIMKMAKEAGVEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRMEL 180 Query: 181 PKKPAVAVSSQQMESCRAEIQENHDDTYGVPSLEELGFPTEGLGPAVWQGGETEALARLD 240 PKKPAVAVSSQQMESCRAEIQENHDDTYGVPSLEELGFPTEGLGPAVWQGGETEALARLD Sbjct: 181 PKKPAVAVSSQQMESCRAEIQENHDDTYGVPSLEELGFPTEGLGPAVWQGGETEALARLD 240 Query: 241 KHLERKAWVANYERPRMNANSLLASPTGLSPYLRFGCLSCRLFYYRLWDLYKKVKRNSTP 300 KHLERKAWVANYERPRMNANSLLASPTGLSPYLRFGCLSCRLFYYRLWDLYKKVKRNSTP Sbjct: 241 KHLERKAWVANYERPRMNANSLLASPTGLSPYLRFGCLSCRLFYYRLWDLYKKVKRNSTP 300 Query: 301 PLSLFGQLLWREFFYTAATNNPRFDRMEGNPICIQIPWDRNPEALAKWAEGKTGFPWIDA 360 PLSLFGQLLWREFFYTAATNNPRFDRMEGNPICIQIPWDRNPEALAKWAEGKTGFPWIDA Sbjct: 301 PLSLFGQLLWREFFYTAATNNPRFDRMEGNPICIQIPWDRNPEALAKWAEGKTGFPWIDA 360 Query: 361 IMTQLRQEGWIHHLARHAVACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSC 420 IMTQLRQEGWIHHLARHAVACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSC Sbjct: 361 IMTQLRQEGWIHHLARHAVACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSC 420 Query: 421 SAFFQQFFHCYCPVGFGRRTDPSGDYIRRYLPKLKGFPSRYIYEPWNAPESVQKAAKCII 480 SAFFQQFFHCYCPVGFGRRTDPSGDYIRRYLPKLKGFPSRYIYEPWNAPESVQKAAKCII Sbjct: 421 SAFFQQFFHCYCPVGFGRRTDPSGDYIRRYLPKLKGFPSRYIYEPWNAPESVQKAAKCII 480 Query: 481 GVDYPRPIVNHAETSRLNIERMKQIYQQLSRYRGLCLLASVPSCVEDLSHPVAEPGSSQA 540 GVDYPRPIVNHAETSRLNIERMKQIYQQLSRYRGLCLLASVPSCVEDLSHPVAEPGSSQA Sbjct: 481 GVDYPRPIVNHAETSRLNIERMKQIYQQLSRYRGLCLLASVPSCVEDLSHPVAEPGSSQA 540 Query: 541 GSIS 544 GSIS Sbjct: 541 GSIS 544 >4K0R-A nrPDB Length = 617 Score = 726 bits (1875), Expect = 0.0, Method: Composition-based stats. Identities = 405/504 (80%), Positives = 460/504 (91%) Query: 20 GASSVHWFRKGLRLHDNPALLAAVRGARCVRCVYILDPWFAASSSVGINRWRFLLQSLED 79 G ++VHWFRKGLRLHDNPAL ++GA +RCVYILDPWFA SS+VGINRWRFLLQ LED Sbjct: 2 GVNAVHWFRKGLRLHDNPALKECIQGADTIRCVYILDPWFAGSSNVGINRWRFLLQCLED 61 Query: 80 LDTSLRKLNSRLFVVRGQPADVFPRLFKEWGVTRLTFEYDSEPFGKERDAAIMKMAKEAG 139 LD +LRKLNSRLFV+RGQPADVFPRLFKEW +T+L+ EYDSEPFGKERDAAI K+A EAG Sbjct: 62 LDANLRKLNSRLFVIRGQPADVFPRLFKEWNITKLSIEYDSEPFGKERDAAIKKLATEAG 121 Query: 140 VEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRMELPKKPAVAVSSQQMESCRAE 199 VEV+ SHTLYDLD+IIELNG +PPLTYKRFQ L+S+ME + PA ++S + C Sbjct: 122 VEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLVSKMEPLEMPADTITSDVIGKCMTP 181 Query: 200 IQENHDDTYGVPSLEELGFPTEGLGPAVWQGGETEALARLDKHLERKAWVANYERPRMNA 259 + ++HD+ YGVPSLEELGF T+GL AVW GGETEAL RL++HLERKAWVAN+ERPRMNA Sbjct: 182 LSDDHDEKYGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVANFERPRMNA 241 Query: 260 NSLLASPTGLSPYLRFGCLSCRLFYYRLWDLYKKVKRNSTPPLSLFGQLLWREFFYTAAT 319 NSLLASPTGLSPYLRFGCLSCRLFY++L DLYKKVK+NS+PPLSL+GQLLWREFFYTAAT Sbjct: 242 NSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWREFFYTAAT 301 Query: 320 NNPRFDRMEGNPICIQIPWDRNPEALAKWAEGKTGFPWIDAIMTQLRQEGWIHHLARHAV 379 NNPRFD+MEGNPIC+QIPWD+NPEALAKWAEG+TGFPWIDAIMTQLRQEGWIHHLARHAV Sbjct: 302 NNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHAV 361 Query: 380 ACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSCSAFFQQFFHCYCPVGFGRR 439 ACFLTRGDLW+SWE G++VF+ELLLDAD+S+NAGSWMWLSCS+FFQQFFHCYCPVGFGRR Sbjct: 362 ACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQFFHCYCPVGFGRR 421 Query: 440 TDPSGDYIRRYLPKLKGFPSRYIYEPWNAPESVQKAAKCIIGVDYPRPIVNHAETSRLNI 499 TDP+GDYIRRYLP L+GFP++YIY+PWNAPE +QK AKC+IGV+YP+P+VNHAE SRLNI Sbjct: 422 TDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEASRLNI 481 Query: 500 ERMKQIYQQLSRYRGLCLLASVPS 523 ERMKQIYQQLSRYRGL LLASVPS Sbjct: 482 ERMKQIYQQLSRYRGLGLLASVPS 505 >3FY4-A nrPDB Length = 537 Score = 614 bits (1582), Expect = e-176, Method: Composition-based stats. Identities = 249/502 (49%), Positives = 335/502 (66%), Gaps = 19/502 (3%) Query: 18 ADGASSVHWFRKGLRLHDNPALLAAVRGARCVRCVYILDPWFA---------ASSSVGIN 68 A G+ S+ WFRKGLR+HDNPAL A +G+ + V+++DP + SS G+N Sbjct: 2 ATGSGSLIWFRKGLRVHDNPALEYASKGSEFMYPVFVIDPHYMESDPSAFSPGSSRAGVN 61 Query: 69 RWRFLLQSLEDLDTSLRKLNSRLFVVRGQPADVFPRLFKEWGVTRLTFEYDSEPFGKERD 128 R RFLL+SL+DLD+SL+KL SRL V +G+P +V R +EW V RL FEYD++P+ + D Sbjct: 62 RIRFLLESLKDLDSSLKKLGSRLLVFKGEPGEVLVRCLQEWKVKRLCFEYDTDPYYQALD 121 Query: 129 AAIMKMAKEAGVEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRMELPKKPAVAV 188 + A GVEV + SHTL++ IIE NG KPPL+Y+ F +++ +P+ A Sbjct: 122 VKVKDYASSTGVEVFSPVSHTLFNPAHIIEKNGGKPPLSYQSF------LKVAGEPSCAK 175 Query: 189 SSQQMESCRAEI--QENHDDTYGVPSLEELGFPTEGLGP-AVWQGGETEALARLDKHLER 245 S M + VPSLEELG+ + ++GGE+EAL RL K + Sbjct: 176 SELVMSYSSLPPIGDIGNLGISEVPSLEELGYKDDEQADWTPFRGGESEALKRLTKSISD 235 Query: 246 KAWVANYERPRMNANSLLA-SPTGLSPYLRFGCLSCRLFYYRLWDLYKKVKRNSTPPLSL 304 KAWVAN+E+P+ + ++ L + T +SPYL+FGCLS R FY L ++YK VK++++PP+SL Sbjct: 236 KAWVANFEKPKGDPSAFLKPATTVMSPYLKFGCLSSRYFYQCLQNIYKDVKKHTSPPVSL 295 Query: 305 FGQLLWREFFYTAATNNPRFDRMEGNPICIQIPWDRNPEALAKWAEGKTGFPWIDAIMTQ 364 GQLLWREFFYT A P FD+M+GN IC QIPW+ + LA W +GKTG+PWIDAIM Q Sbjct: 296 LGQLLWREFFYTTAFGTPNFDKMKGNRICKQIPWNEDHAMLAAWRDGKTGYPWIDAIMVQ 355 Query: 365 LRQEGWIHHLARHAVACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSCSAFF 424 L + GW+HHLARH VACFLTRGDL++ WE G VF+ LL+D+D+++N G+WMWLSCS+FF Sbjct: 356 LLKWGWMHHLARHCVACFLTRGDLFIHWEQGRDVFERLLIDSDWAINNGNWMWLSCSSFF 415 Query: 425 QQFFHCYCPVGFGRRTDPSGDYIRRYLPKLKGFPSRYIYEPWNAPESVQKAAKCIIGVDY 484 QF Y P+ FG++ DP G YIR +LP LK P +YIYEPW AP SVQ A CI+G DY Sbjct: 416 YQFNRIYSPISFGKKYDPDGKYIRHFLPVLKDMPKQYIYEPWTAPLSVQTKANCIVGKDY 475 Query: 485 PRPIVNHAETSRLNIERMKQIY 506 P+P+V H S+ +M + Y Sbjct: 476 PKPMVLHDSASKECKRKMGEAY 497 >4JZY-A nrPDB Length = 536 Score = 564 bits (1452), Expect = e-161, Method: Composition-based stats. Identities = 208/513 (40%), Positives = 291/513 (56%), Gaps = 19/513 (3%) Query: 15 SMGADGASSVHWFRKGLRLHDNPALLAAVR---GARCVRCVYILDPWFAASSSVGINRWR 71 +M GA+ + WFR GLRLHDNPALLAA+ + V+I D A + +VG NR R Sbjct: 1 AMATRGANVI-WFRHGLRLHDNPALLAALADKDQGIALIPVFIFDGESAGTKNVGYNRMR 59 Query: 72 FLLQSLEDLDTSLRKLN---SRLFVVRGQPADVFPRLFKEWGVTRLTFEYDSEPFGKERD 128 FLL SL+D+D L+ RL V G+PA +F RL ++ + R+ E D EP ERD Sbjct: 60 FLLDSLQDIDDQLQAATDGRGRLLVFEGEPAYIFRRLHEQVRLHRICIEQDCEPIWNERD 119 Query: 129 AAIMKMAKEAGVEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRMELPKKPAVAV 188 +I + +E ++ V + SHTL+D +IE NG PPLTY+ F + + LP +P Sbjct: 120 ESIRSLCRELNIDFVEKVSHTLWDPQLVIETNGGIPPLTYQMFLHTVQIIGLPPRPTADA 179 Query: 189 SSQQMESCRAEIQENHDDTYG--VPSLEELGFPTEG---LGPAVWQGGETEALARLDKHL 243 + + + +P+ E + L W+GGET+AL LD+ L Sbjct: 180 RLEDATFVELDPEFCRSLKLFEQLPTPEHFNVYGDNMGFLAKINWRGGETQALLLLDERL 239 Query: 244 --ERKAWVANYERPRMNANSLLASPTGLSPYLRFGCLSCRLFYYRLWDLYKKVKRN--ST 299 E+ A+ + P ++ SP +S +LRFGCLS R FY+ + DL+K V+ T Sbjct: 240 KVEQHAFERGFYLPNQALPNIHDSPKSMSAHLRFGCLSVRRFYWSVHDLFKNVQLGVQMT 299 Query: 300 PPLSLFGQLLWREFFYTAATNNPRFDRMEGNPICIQIPWDR-NPEALAKWAEGKTGFPWI 358 + GQL+WRE+FYT + NNP +DRMEGN IC+ IPW + N L W G+TGFP I Sbjct: 300 GGAHITGQLIWREYFYTMSVNNPNYDRMEGNDICLSIPWAKPNENLLQSWRLGQTGFPLI 359 Query: 359 DAIMTQLRQEGWIHHLARHAVACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWL 418 D M QL EGW+HH R+ VA FLTRG LW SWE G++ F + LLDAD+SV AG+WMW+ Sbjct: 360 DGAMRQLLAEGWLHHTLRNTVATFLTRGGLWQSWEHGLQHFLKYLLDADWSVCAGNWMWV 419 Query: 419 SCSAFFQQFFH--CYCPVGFGRRTDPSGDYIRRYLPKLKGFPSRYIYEPWNAPESVQKAA 476 S SAF + CPV +R DP G YI++Y+P+L P +++EPW Q+ Sbjct: 420 SSSAFERLLDSSLVTCPVALAKRLDPDGTYIKQYVPELMNVPKEFVHEPWRMSAEQQEQY 479 Query: 477 KCIIGVDYPRPIVNHAETSRLNIERMKQIYQQL 509 +C+IGV YP I++ + + N+ MK + L Sbjct: 480 ECLIGVHYPERIIDLSMAVKRNMLAMKSLRNSL 512 >1NP7-A nrPDB Length = 489 Score = 543 bits (1400), Expect = e-155, Method: Composition-based stats. Identities = 141/494 (28%), Positives = 227/494 (45%), Gaps = 24/494 (4%) Query: 23 SVHWFRKGLRLHDNPALLAAVRGARCVRCVYILDPWFAASSS-----VGINRWRFLLQSL 77 + WFR LRLHD+ L A++ + VY DP A + G R FL QS+ Sbjct: 8 VLVWFRNDLRLHDHEPLHRALKSGLAITAVYCYDPRQFAQTHQGFAKTGPWRSNFLQQSV 67 Query: 78 EDLDTSLRKLNSRLFVVRGQPADVFPRLFKEWGVTRLTFEYDSEPFGKERDAA--IMKMA 135 ++L SL+K+ ++L V G P V P++ K+ + Y E +E D ++K Sbjct: 68 QNLAESLQKVGNKLLVTTGLPEQVIPQIAKQINAKTIY--YHREVTQEELDVERNLVKQL 125 Query: 136 KEAGVEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRMELPKKPAVAVSSQQMES 195 G+E TL + + + Q P + +F+ I + ++ +P SQ + S Sbjct: 126 TILGIEAKGYWGSTLCHPEDL-PFSIQDLPDLFTKFRKDIEKKKISIRPCFFAPSQLLPS 184 Query: 196 CRAEIQENHDDTYGVPSLEELGFPTEGLGPAVWQGGETEALARLDKHLERKAWVANYERP 255 +++ P ++ F + +QGGET LARL + + +Y+ Sbjct: 185 PNIKLELTAPPPEFFP---QINFDHRSV--LAFQGGETAGLARLQDYFWHGDRLKDYKET 239 Query: 256 RMNANSLLASPTGLSPYLRFGCLSCRLFYYRLWDLYKKVKRNSTPPLSLFGQLLWREFFY 315 R + SP+L GCLS R Y + Y++ + ++ L +LLWR+FF Sbjct: 240 RNGMVGA-DYSSKFSPWLALGCLSPRFIYQEVK-RYEQERVSNDSTHWLIFELLWRDFFR 297 Query: 316 TAA--TNNPRFDRMEGNPICIQIPWDRNPEALAKWAEGKTGFPWIDAIMTQLRQEGWIHH 373 A N F+R G + PW + W G+TG+P +DA M +L G++ + Sbjct: 298 FVAQKYGNKLFNR--GGLLNKNFPWQEDQVRFELWRSGQTGYPLVDANMRELNLTGFMSN 355 Query: 374 LARHAVACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSCSAFFQQFFHCYCP 433 R VA FL + +L + W G F+ L+D D N G+W + + + F + Sbjct: 356 RGRQNVASFLCK-NLGIDWRWGAEWFESCLIDYDVCSNWGNWNYTAGIGNDARDFRYFNI 414 Query: 434 VGFGRRTDPSGDYIRRYLPKLKGFPSRYIYEPWNAPESVQKAAKCIIGVDYPRPIVNHAE 493 ++ DP G Y+R +LP+LK P I++PW + QK +GVDYPRP VN + Sbjct: 415 PKQSQQYDPQGTYLRHWLPELKNLPGDKIHQPWLLSATEQKQWGVQLGVDYPRPCVNFHQ 474 Query: 494 T--SRLNIERMKQI 505 + +R IE+M I Sbjct: 475 SVEARRKIEQMGVI 488 >4U63-A nrPDB Length = 498 Score = 519 bits (1336), Expect = e-147, Method: Composition-based stats. Identities = 140/488 (28%), Positives = 217/488 (44%), Gaps = 21/488 (4%) Query: 21 ASSVHWFRKGLRLHDNPALLAAVRGARCVRCVYILDPWFAASSSVGINRWRFLLQSLEDL 80 A + WFRK LRL DN ALLAAV V VYI +A G W +L SL L Sbjct: 25 APVIVWFRKDLRLSDNLALLAAVEHGGPVIPVYIR--EKSAGPLGGAQEW-WLHHSLAAL 81 Query: 81 DTSLRKLNSRLFVVRGQPADVFPRLFKEWGVTRLTFEYDSEPFGKERDAAIMKMAKEAGV 140 +SL K RL + G + L E G + + +P G D A+ + ++ G+ Sbjct: 82 SSSLEKAGGRLVLASGDAERILRDLISETGADTVVWNRRYDPTGMATDKALKQKLRDDGL 141 Query: 141 EVVTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRMELPKKPAVAVSSQQMESCRAEI 200 V + + L++ R+ +G P Y F + + P PA S + Sbjct: 142 TVRSFSGQLLHEPSRLQTKSGG-PYRVYTPFWRALEGSDEPHAPADPPKSLTAPKVWPK- 199 Query: 201 QENHDDTYGVPSLEELGFPTEGLGPAVWQGGETEALARLDKHLER--KAWVANYERPRMN 258 E + +P+ + +W GET AL +LD ++ K + + P Sbjct: 200 SEKLSNWKLLPTKPDWAKDFSD----IWTPGETGALDKLDDFIDGALKGYEEGRDFPAKP 255 Query: 259 ANSLLASPTGLSPYLRFGCLSCRLFYYRLWDLYKKVKRNSTPPLSLFGQLLWREFFYTAA 318 A SL LSP+L G +S ++ L + + N +++WREF Y Sbjct: 256 ATSL------LSPHLAAGEISPAAVWHATKGLSRHIASNDIS--RFRKEIVWREFCYHLL 307 Query: 319 TNNPRFDRMEGNPICIQIPWDRNPEALAKWAEGKTGFPWIDAIMTQLRQEGWIHHLARHA 378 + P N W + ++ W G TG+P +DA M QL Q G +H+ R Sbjct: 308 FHFPELGEKNWNDSFDAFSWRDDEKSFKAWTRGMTGYPIVDAGMRQLWQHGTMHNRVRMI 367 Query: 379 VACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSCSA-FFQQFFHCYCPVGFG 437 VA FL + L + W G + F + L+DAD + NA +W W++ S FF + P+ G Sbjct: 368 VASFLIK-HLLIDWRKGEKWFRDTLVDADPASNAANWQWVAGSGADASPFFRIFNPILQG 426 Query: 438 RRTDPSGDYIRRYLPKLKGFPSRYIYEPWNAPESVQKAAKCIIGVDYPRPIVNHAETSRL 497 + D GDY+RR++P+L+ +YI++P+ AP+ K A +G YP PIV+H + Sbjct: 427 EKFDGDGDYVRRFVPELEKLERKYIHKPFEAPKDALKKAGVELGKTYPLPIVDHGKARER 486 Query: 498 NIERMKQI 505 + + Sbjct: 487 ALAAYAAV 494 >1OWP-A nrPDB Length = 484 Score = 493 bits (1270), Expect = e-140, Method: Composition-based stats. Identities = 136/493 (27%), Positives = 227/493 (46%), Gaps = 26/493 (5%) Query: 20 GASSVHWFRKGLRLHDNPALLAAVRGARCVRCVYILDPWFAASSSVGINRWRFLLQSLED 79 A + W R+ LRL DN L AA + + ++ LDP S+ + R +L L++ Sbjct: 2 AAPILFWHRRDLRLSDNIGLAAARAQSAQLIGLFCLDPQILQSADMAPARVAYLQGCLQE 61 Query: 80 LDTSLRKLNSRLFVVRGQPADVFPRLFKEWGVTRLTFEYDSEPFGKERDAAIMKMAKEAG 139 L ++ SRL +++G P + P+L ++ + + D EP+G++RD + K AG Sbjct: 62 LQQRYQQAGSRLLLLQGDPQHLIPQLAQQLQAEAVYWNQDIEPYGRDRDGQVAAALKTAG 121 Query: 140 VEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRMELPKKPAVAVSSQQMESCRAE 199 + V L+ D+I+ +G P Y F PK VA ++ ++ + Sbjct: 122 IRAVQLWDQLLHSPDQILSGSG-NPYSVYGPFWKNWQ--AQPKPTPVATPTELVDLSPEQ 178 Query: 200 IQENHD-DTYGVPSLEELGFPTEGLGPAVWQGGETEALARLDKHLERKAWVANYERPRMN 258 + +P+L++LGF +G P + GET A+ARL + +R +A+Y+ R Sbjct: 179 LTAIAPLLLSELPTLKQLGFDWDGGFPV--EPGETAAIARLQEFCDRA--IADYDPQR-- 232 Query: 259 ANSLLASPTGLSPYLRFGCLSCRLFYYRLWDLYKKVK--RNSTPPLSLFGQLLWREFFYT 316 A +GLSP L+FG + R + + + +L WREF+ Sbjct: 233 NFPAEAGTSGLSPALKFGAIGIRQAWQAASAAHALSRSDEARNSIRVWQQELAWREFYQH 292 Query: 317 AATNNPRFDRMEGNPICIQIPWDRNPEALAKWAEGKTGFPWIDAIMTQLRQEGWIHHLAR 376 A + P + Q PW+ W + +TG+P +DA M QL + GW+H+ R Sbjct: 293 ALYHFPSLADGPYRSLWQQFPWENREALFTAWTQAQTGYPIVDAAMRQLTETGWMHNRCR 352 Query: 377 HAVACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSCSAFFQQFFHCYCPVGF 436 VA FLT+ DL + W G + F + L+D D + N G W W + S + + P Sbjct: 353 MIVASFLTK-DLIIDWRRGEQFFMQHLVDGDLAANNGGWQWSASSGMDPKPLRIFNPASQ 411 Query: 437 GRRTDPSGDYIRRYLPKLKGFPSRYIYEPWNAPESVQKAAKCIIGVDYPRPIVNHAETSR 496 ++ D + YI+R+LP+L+ +++ + + I YP PIVNH Sbjct: 412 AKKFDATATYIKRWLPELR-----HVH----PKDLISGEITPIERRGYPAPIVNH----N 458 Query: 497 LNIERMKQIYQQL 509 L ++ K +Y QL Sbjct: 459 LRQKQFKALYNQL 471 >1DNP-A nrPDB Length = 471 Score = 484 bits (1246), Expect = e-137, Method: Composition-based stats. Identities = 133/494 (26%), Positives = 211/494 (42%), Gaps = 38/494 (7%) Query: 24 VHWFRKGLRLHDNPALLAAVRGARC-VRCVYILDPWFAASSSVGINRWRFLLQSLEDLDT 82 + WFR+ LRLHDN AL AA R + V +YI P A+ ++ + + L L Sbjct: 4 LVWFRQDLRLHDNLALAAACRNSSARVLALYIATPRQWATHNMSPRQAELINAQLNGLQI 63 Query: 83 SLRKLNSRLFVVRGQP----ADVFPRLFKEWGVTRLTFEYDSEPFGKERDAAIMKMAKEA 138 +L + L ++ ++ E VT L + Y E + RD + + + Sbjct: 64 ALAEKGIPLLFREVDDFVASVEIVKQVCAENSVTHLFYNYQYEVNERARDVEVERALR-- 121 Query: 139 GVEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRMELPKKPA-VAVSSQQMESCR 197 VV E +D I+ PP + ++ P K A + + M C Sbjct: 122 --NVVCEG----FDDSVIL------PPGAVMTGNHEMYKVFTPFKNAWLKRLREGMPECV 169 Query: 198 AEIQENHDDTYGVPSLEELGFPTEGLGPAVWQGGETEALARLDKHLERKAWVANYERPRM 257 A + + L +P + A + E A+A+L + + A YE+ R Sbjct: 170 AAPKVRSSGSIEPSPSITLNYPRQSFDTAHFPVEEKAAIAQLRQFCQNGA--GEYEQQR- 226 Query: 258 NANSLLASPTGLSPYLRFGCLSCRLFYYRLWDLYKKVKRNSTPPLSLFGQLLWREFFYTA 317 + + LS L G LS R +RL + + L +L+WREF+ Sbjct: 227 -DFPAVEGTSRLSASLATGGLSPRQCLHRLLAEQPQALDGGAGSVWL-NELIWREFYRHL 284 Query: 318 ATNNPRFDRMEGNPIC---IQIPWDRNPEALAKWAEGKTGFPWIDAIMTQLRQEGWIHHL 374 T +P + P ++ W NP L W EGKTG+P +DA M QL GW+H+ Sbjct: 285 ITYHPSL--CKHRPFIAWTDRVQWQSNPAHLQAWQEGKTGYPIVDAAMRQLNSTGWMHNR 342 Query: 375 ARHAVACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSCSAFF-QQFFHCYCP 433 R A FL + DL + W G R F L+D D + N G W W + + +F + P Sbjct: 343 LRMITASFLVK-DLLIDWREGERYFMSQLIDGDLAANNGGWQWAASTGTDAAPYFRIFNP 401 Query: 434 VGFGRRTDPSGDYIRRYLPKLKGFPSRYIYEPWNAPESVQKAAKCIIGVDYPRPIVNHAE 493 G + D G++IR++LP+L+ P + ++EPW + A K + +DYP+PIV H E Sbjct: 402 TTQGEKFDHEGEFIRQWLPELRDVPGKVVHEPW------KWAQKAGVTLDYPQPIVEHKE 455 Query: 494 TSRLNIERMKQIYQ 507 + + + Sbjct: 456 ARVQTLAAYEAARK 469 >1U3C-A nrPDB Length = 509 Score = 475 bits (1221), Expect = e-134, Method: Composition-based stats. Identities = 135/498 (27%), Positives = 218/498 (43%), Gaps = 33/498 (6%) Query: 24 VHWFRKGLRLHDNPALLAAVRGARCVRCVYILDPWFAASSSVGINRWRFLLQSLEDLDTS 83 + WFR+ LR+ DNPAL AAVR V +++ P G +L SL LD+S Sbjct: 15 IVWFRRDLRVEDNPALAAAVRAGP-VIALFVWAPEEEGHYHPGRVSRWWLKNSLAQLDSS 73 Query: 84 LRKLNSRLFVVRG-QPADVFPRLFKEWGVTRLTFEYDSEPFGKERDAAIMKMAKEAGVEV 142 LR L + L R + K G +++ F + +P RD + G+ V Sbjct: 74 LRSLGTCLITKRSTDSVASLLDVVKSTGASQIFFNHLYDPLSLVRDHRAKDVLTAQGIAV 133 Query: 143 VTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRM-------ELPKKPAVAVSSQQMES 195 + N+ LY+ + + G+ + F A R E P P + S + Sbjct: 134 RSFNADLLYEPWEVTDELGRP----FSMFAAFWERCLSMPYDPESPLLPPKKIISGDVSK 189 Query: 196 CRAEIQENHDDTYGVPSLEELGFPTEGLGPAVWQGGETEALARLDKHLERKAWVANYERP 255 C A+ DD+ + L W G + L + + Y + Sbjct: 190 CVADPLVFEDDS---------EKGSNALLARAWSPGWSNGDKALTTFING--PLLEYSKN 238 Query: 256 RMNANSLLASPTGLSPYLRFGCLSCRLFYYRLW----DLYKKVKRNSTPPLSLFGQLL-W 310 R A+S A+ + LSP+L FG +S R ++ + + ++LF + + Sbjct: 239 RRKADS--ATTSFLSPHLHFGEVSVRKVFHLVRIKQVAWANEGNEAGEESVNLFLKSIGL 296 Query: 311 REFFYTAATNNPRFDRMEGNPICIQIPWDRNPEALAKWAEGKTGFPWIDAIMTQLRQEGW 370 RE+ + N+P PW + W +G+TG+P +DA M +L GW Sbjct: 297 REYSRYISFNHPYSHERPLLGHLKFFPWAVDENYFKAWRQGRTGYPLVDAGMRELWATGW 356 Query: 371 IHHLARHAVACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSCSA-FFQQFFH 429 +H R V+ L + W G++ F + LLDAD +A W +++ + ++F Sbjct: 357 LHDRIRVVVSS-FFVKVLQLPWRWGMKYFWDTLLDADLESDALGWQYITGTLPDSREFDR 415 Query: 430 CYCPVGFGRRTDPSGDYIRRYLPKLKGFPSRYIYEPWNAPESVQKAAKCIIGVDYPRPIV 489 P G + DP+G+Y+RR+LP+L P+ +I+ PWNAPESV +AA +G +YP PIV Sbjct: 416 IDNPQFEGYKFDPNGEYVRRWLPELSRLPTDWIHHPWNAPESVLQAAGIELGSNYPLPIV 475 Query: 490 NHAETSRLNIERMKQIYQ 507 E E + Q++Q Sbjct: 476 GLDEAKARLHEALSQMWQ 493 >2VTB-B nrPDB Length = 525 Score = 459 bits (1181), Expect = e-129, Method: Composition-based stats. Identities = 122/459 (26%), Positives = 204/459 (44%), Gaps = 35/459 (7%) Query: 23 SVHWFRKGLRLHDNPALLAAVRGARCVRCVYILDP------WFAASSSVGINRWRFLLQS 76 ++ WFR LR+ DN AL A + + VY LDP F G R FL++ Sbjct: 43 TILWFRNDLRVLDNDALYKAWSSSDTILPVYCLDPRLFHTTHFFNFPKTGALRGGFLMEC 102 Query: 77 LEDLDTSLRKLNSRLFVVRGQPADVFPRLFKEWGVTRLTFEYD--SEPFGKER--DAAIM 132 L DL +L K L + G+P ++ P L K++G + + SE ER + + Sbjct: 103 LVDLRKNLMKRGLNLLIRSGKPEEILPSLAKDFGARTVFAHKETCSEEVDVERLVNQGLK 162 Query: 133 KMAKEAGVEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQALIS-RMELPKKPAVAVSSQ 191 ++ +E++ T+Y D + + P Y +F+ + + + + +S Sbjct: 163 RVGNSTKLELI--WGSTMYHKDDL-PFDVFDLPDVYTQFRKSVEAKCSIRSSTRIPLSLG 219 Query: 192 QMESCRAEIQENHDDTYGVPSLEELGF-PTEGLGPAVWQGGETEALARLDKHLERKAWVA 250 S DD VP+LE+LG P E + GGE+ + R+ ++ +K + Sbjct: 220 PTPSV--------DDWGDVPTLEKLGVEPQEVTRGMRFVGGESAGVGRVFEYFWKKDLLK 271 Query: 251 NYERPRMNANSLLA--SPTGLSPYLRFGCLSCRLFYYRLWDLYKKVKRNSTPPLSLFGQL 308 Y+ R N +L T SP+L FGC+S R Y + K+ N++ LF +L Sbjct: 272 VYKETR---NGMLGPDYSTKFSPWLAFGCISPRFIYEEVQRYEKERVANNSTYWVLF-EL 327 Query: 309 LWREFFYTAA--TNNPRFDRMEGNPICIQIPWDRNPEALAKWAEGKTGFPWIDAIMTQLR 366 +WR++F + N F G P + W ++ + W + KTG+P IDA M +L Sbjct: 328 IWRDYFRFLSIKCGNSLFHL--GGPRNVNGKWSQDQKLFESWRDAKTGYPLIDANMKELS 385 Query: 367 QEGWIHHLARHAVACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSCSAFFQQ 426 G++ + R V FL R D+ + W G F+ LLD D N G+W + + ++ Sbjct: 386 TTGFMSNRGRQIVCSFLVR-DMGLDWRMGAEWFETCLLDYDPCSNYGNWTYGAGVNDPRE 444 Query: 427 FFHCYCPVGFGRRTDPSGDYIRRYLPKLKGFPSRYIYEP 465 + + DP G+Y+ +L +L+ P + P Sbjct: 445 -DRYFSIPKQAQNYDPEGEYVAFWLQQLRRLPKEKRHWP 482 >2E0I-A nrPDB Length = 440 Score = 449 bits (1154), Expect = e-126, Method: Composition-based stats. Identities = 125/483 (25%), Positives = 195/483 (40%), Gaps = 59/483 (12%) Query: 24 VHWFRKGLRLHDNPALLAAVRGARCVRCVYILDPWFA-ASSSVGINRWRFLLQSLEDLDT 82 + FR+ LRL DN L A+ V V+I DP + F++ SL +LD Sbjct: 4 IFIFRRDLRLEDNTGLNYALSECDRVIPVFIADPRQLINNPYKSEFAVSFMINSLLELDD 63 Query: 83 SLRKLNSRLFVVRGQPADVFPRLFKEWGVTRLTFEYDSEPFGKERDAAIMKMAKEAGVEV 142 LRK SRL V G+ V R F + V + D PF RD I K+ +E G+E Sbjct: 64 ELRKKGSRLNVFFGEAEKVVSRFFNK--VDAIYVNEDYTPFSISRDEKIRKVCEENGIEF 121 Query: 143 VTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRMELPKKPAVAVSSQQMESCRAEIQE 202 + L K ++ F + + + V V + ++ + Sbjct: 122 KAYEDYLL----------TPKSLFHHRNFTSFYNEV-----SKVKVREPETMEGSFDVTD 166 Query: 203 NHDDTYGVPSLEELGFPTEGLGPAVWQGGETEALARLDKHLERKAWVANYERPRMNANSL 262 + + + + +++ P +++GG E L L ++++ + + P N N Sbjct: 167 SSMNVDFLLTFKKIESP-------LFRGGRREGLYLLHRNVDFR----RRDYPAENNN-- 213 Query: 263 LASPTGLSPYLRFGCLSCRLFYYRLWDLYKKVKRNSTPPLSLFGQLLWREFFYTAATNNP 322 LSP+L+FG +S R YY + +L WR+FF A NP Sbjct: 214 ----YRLSPHLKFGTISMREAYYTQKGKEE-----------FVRELYWRDFFTLLAYYNP 258 Query: 323 RFDRMEGNPICIQIPWDRNPEALAKWAEGKTGFPWIDAIMTQLRQEGWIHHLARHAVACF 382 I W+ N W EG+TG+P IDA M L G+I+ R VA F Sbjct: 259 HVFGHCYRREYDNISWENNESYFEAWKEGRTGYPIIDAGMRMLNSTGYINGRVRMLVAFF 318 Query: 383 LTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSCSAFFQQFFHCYCPVGFGRRTDP 442 L + L+V W G R F L+D D ++N G+W W++ + F + P + DP Sbjct: 319 LVKV-LFVDWRWGERYFATKLVDYDPAINNGNWQWIASTGVD-YMFRVFNPWKQQEKFDP 376 Query: 443 SGDYIRRYLPKLKGFPSRYIYEPWNAPESVQKAAKCIIGVDYPRPIVNHAETSRLNIERM 502 +I+ ++ +LK P P + K + YP PIVN E Sbjct: 377 EAKFIKEWVEELKDVP----------PSIIHSIYKTKVP-GYPSPIVNWLERVNYVKSEY 425 Query: 503 KQI 505 K + Sbjct: 426 KNV 428 >2J08-A nrPDB Length = 420 Score = 374 bits (961), Expect = e-104, Method: Composition-based stats. Identities = 117/440 (26%), Positives = 168/440 (38%), Gaps = 46/440 (10%) Query: 22 SSVHWFRKGLRLHDNPALLAAVRGARCVRCVYILDPWFAASSSVGINRWRFLLQSLEDLD 81 + W R LRLHD+PALL A+ V V +LDP + R + L+++ L Sbjct: 3 PLLVWHRGDLRLHDHPALLEALARGPVVGLV-VLDP---NNLKTTPRRRAWFLENVRALR 58 Query: 82 TSLRKLNSRLFVVRGQPADVFPRLFKEWGVTRLTFEYDSEPFGKERDAAIMKMAKEAGVE 141 + R L+V+ G P+ K +AA AK Sbjct: 59 EAYRARGGALWVLEGL------------------------PWEKVPEAARRLKAKA---- 90 Query: 142 VVTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRMELPKKPAVAVSSQQMESCRAEIQ 201 V SHT Y R + P + + +LP+ A V + R Sbjct: 91 VYALTSHTPYGRYRDGRVREALPVPLHLLPAPHLLPPDLPR--AYRVYTPFSRLYRGAAP 148 Query: 202 ENHDDTYGVPSLEELGFPTEGLGPAVWQGGETEALARLDKHLERKAWVANYERPRMNANS 261 EE P E G + + GE ALA L LE K ER R++ Sbjct: 149 PLPPPEALPKGPEEGEIPREDPGLPLPEPGEEAALAGLRAFLEAKLPRYAEERDRLDGEG 208 Query: 262 LLASPTGLSPYLRFGCLSCRLFYYRLWDLYKKVKRNSTPPLSLFGQLLWREFFYTAATNN 321 + LSPY G LS RL ++ +R +LLWR+F Y + Sbjct: 209 ----GSRLSPYFALGVLSPRL------AAWEAERRGGEGARKWVAELLWRDFSYHLLYHF 258 Query: 322 PRFDRMEGNPICIQIPWDRNPEALAKWAEGKTGFPWIDAIMTQLRQEGWIHHLARHAVAC 381 P +P PW + W EGKTG P +DA M +L G++ + AR A Sbjct: 259 PWMAERPLDPRFQAFPWQEDEALFQAWYEGKTGVPLVDAAMRELHATGFLSNRARMNAAQ 318 Query: 382 FLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSCSA-FFQQFFHCYCPVGFGRRT 440 F + L + W+ F LLLD D +VN W W +F + PV G R Sbjct: 319 FAVK-HLLLPWKRCEEAFRHLLLDGDRAVNLQGWQWAGGLGVDAAPYFRVFNPVLQGERH 377 Query: 441 DPSGDYIRRYLPKLKGFPSR 460 DP G +++R+ P+ + + Sbjct: 378 DPEGRWLKRWAPEYPSYAPK 397 >5O8D-A nrPDB Length = 484 Score = 155 bits (391), Expect = 6e-38, Method: Composition-based stats. Identities = 71/373 (19%), Positives = 131/373 (35%), Gaps = 30/373 (8%) Query: 22 SSVHWFRKGLRLHDNPALL---AAVRGARC-VRCVYILDPWFAASSSVGINRWRFLLQSL 77 V+W + R DN ALL A + A V V+ L F + GI ++ F+L+ L Sbjct: 40 PVVYWMSRDQRAEDNWALLFSRAIAKEANVPVVVVFCLTDEFLEA---GIRQYEFMLKGL 96 Query: 78 EDLDTSLRKLNSRLFVVRGQPADVFPRLFKEWGVTRLTFEYDSEPFGKERDAAIMKMAKE 137 ++L+ SL + F +RG P + R K++ L D P + ++ I K+ Sbjct: 97 QELEVSLSRKKIPSFFLRGDPGEKISRFVKDYNAGTLVT--DFSPL-RIKNQWIEKVISG 153 Query: 138 AGVEVVTENSHTLYDLDRIIELNGQKP----PLTYKRFQALISRMELPKKPAVAVSSQQM 193 + ++H + + + P Y + + +V Sbjct: 154 ISIPFFEVDAHNVVPCWEASQKHEYAAHTFRPKLYALLPEFLEEFPELEPNSVTPELSAG 213 Query: 194 ESCRAEIQENHDD--TYGVPSLEELGFPTEGLGPAVWQGGETEALARLDKHLERKAWVAN 251 + + + +P L P ++ GE A ++ + + Sbjct: 214 AGMVETLSDVLETGVKALLPERALLKNKDPLFEPWHFEPGEKAAKKVMESFIADRLDSYG 273 Query: 252 YERPRMNANSLLASPTGLSPYLRFGCLSCRLFYYRLWDLYKKVKRNSTPPLSLFGQLLWR 311 + + + LSPYL FG +S + + ++ K + L L+W+ Sbjct: 274 ----ALRNDPTKNMLSNLSPYLHFGQISSQRV---VLEVEKAESNPGSKKAFLDEILIWK 326 Query: 312 EFFYTAATNNPRFDRMEGNPICIQIPWDRNPE-------ALAKWAEGKTGFPWIDAIMTQ 364 E NP +D E P + + + L ++ GKT P +A + Sbjct: 327 EISDNFCYYNPGYDGFESFPSWAKESLNAHRNDVRSHIFTLEEFEAGKTHDPLWNASQME 386 Query: 365 LRQEGWIHHLARH 377 L G +H R Sbjct: 387 LLSTGKMHGYTRM 399 >3UMV-A nrPDB Length = 506 Score = 77.9 bits (190), Expect = 1e-14, Method: Composition-based stats. Identities = 90/463 (19%), Positives = 156/463 (33%), Gaps = 57/463 (12%) Query: 23 SVHWFRKGLRLHDNP----ALLAAVRGARCVRCVYILDPWFAASSSVGINRWRFLLQSLE 78 V+W + RL DN A A A + + L P S + FLL+ L Sbjct: 40 VVYWMLRDQRLADNWALLHAAGLAAASASPLAVAFALFPRPF-LLSARRRQLGFLLRGLR 98 Query: 79 DLDTSLRKLNSRLFVVRGQPADVFPRLFKEWGVTRLTFEYD-SEPFGKERDAAIMKMAKE 137 L + F+ G PA++ P L + G + L ++ P + DA + + +E Sbjct: 99 RLAADAAARHLPFFLFTGGPAEI-PALVQRLGASTLVADFSPLRPVREALDAVVGDLRRE 157 Query: 138 A-GVEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRMELPKKPAVAVSSQQMESC 196 A GV V ++H + + K + K F+ +S++ V ++ + Sbjct: 158 APGVAVHQVDAHNVVPVW----TASAKMEYSAKTFRGKVSKV----MDEYLVEFPELPAV 209 Query: 197 RAEIQENHDDTYGVPSLEELGFPTEGLGPAVW-QGGETEALARLDKHLER--KAWVANYE 253 +E + + + E + W + GE A+ L + + +YE Sbjct: 210 VPWDREQPEGVDWDALIARVCSEAENVPEIDWCEPGEEAAIEALLGSKDGFLTKRIKSYE 269 Query: 254 RPRMNANSLLASPTGLSPYLRFGCLSCRLFYYRLWDLYKKVKRNSTPPLSLFGQ--LLWR 311 R N + + +GLSPYL FG +S + KK + S + F + ++ R Sbjct: 270 TDR-NDPTKPRALSGLSPYLHFGHISAQRCALEA----KKCRHLSPKSVDAFLEELVVRR 324 Query: 312 EFFYTAATNNPRFDRMEGNPICIQIPW-----DRNPEAL--AKWAEGKTGFPWIDAIMTQ 364 E P++D + G + D+ + KT P +A + Sbjct: 325 ELADNFCYYQPQYDSLSGAWEWARKTLMDHAADKREHIYTREQLENAKTHDPLWNASQLE 384 Query: 365 LRQEGWIHHLARHAVACFLTRGDLWVSWESGVRVFDELL--------LDADFSVNAGSWM 416 + G +H R A + W SG +D M Sbjct: 385 MVHHGKMHGFMRMYWAK------KILEWTSGPEEALSTAIYLNDKYEIDGRDPSGYVGCM 438 Query: 417 WLSCSAFF-----QQFF---HCYCPVGFGRRTDPSG--DYIRR 449 W C + F G R+ D Y++R Sbjct: 439 WSICGLHDQGWKERPVFGKIRYMNYAGCKRKFDVDAYISYVKR 481 >4Z5P-A nrPDB Length = 400 Score = 34.4 bits (77), Expect = 0.15, Method: Composition-based stats. Identities = 50/299 (16%), Positives = 80/299 (26%), Gaps = 52/299 (17%) Query: 19 DGASSVHWFRKGLRLHDNPALLAAVRGARCVRCVYILDP------WFAASSSVGINRWRF 72 A+S F + D P R + + LDP S + R Sbjct: 56 RAANSDPRFSRAQIGEDTPRTTPLARRSDTILS---LDPPEHTRLRRLLSKAFTARRMGA 112 Query: 73 LLQSLEDLDTSLRKLNSRLFVVRGQPADVFPRLFKEWGVTRLT------------FEYDS 120 + LE+L L R G PAD+ L + + + + F++ S Sbjct: 113 MQSWLEELFAGLLDGVER----TGHPADIVRDLAQPFTIAVICRLLGVPYEDRGRFQHWS 168 Query: 121 EPF----------GKERDAAIMKMAKEA-------------GVEVVTENSHTLYDLDRII 157 E DA+I + GV V + D +I Sbjct: 169 EVIMSTTAYSKEEAVSADASIRAYLADLVSARRAAPHDDLLGVLVSARDDDDRLTEDELI 228 Query: 158 ELNGQKPPLTYKRFQALISRMELPKKPAVAVSSQQMESCRAEIQENHDDTYGVPSLEELG 217 ++ + M S E + + VP +G Sbjct: 229 TFGVTLLVAGHETSAHQLGNMVYALLTHEDQLSLLREQPELLPRAVEELLRFVPLGNGVG 288 Query: 218 FPTEGLGPAVWQGGETEALARLDKHLERKAWVANYERPRMNANSLLASPTGLSPYLRFG 276 L GG R + + A AN + + L +P+L FG Sbjct: 289 NARIALEDVELSGG----TVRAGEGVVAAAVNANRDPRAFDDPDRLDITREKNPHLAFG 343 >3E6I-A nrPDB Length = 476 Score = 33.6 bits (75), Expect = 0.25, Method: Composition-based stats. Identities = 46/250 (18%), Positives = 80/250 (32%), Gaps = 29/250 (11%) Query: 53 YILDPWFAASSSVGINRWRFLLQSLEDLDTSLRKLNSRLFVVRGQPADVFPRLFKEWGVT 112 Y+ + S+ N R L L + RL+ + G V F T Sbjct: 224 YVSERVKEHHQSLDPNCPRDLTDCLLVEMEKEKHSAERLYTMDGITVTVADLFFAGTETT 283 Query: 113 RLTFEY------DSEPFGKERDAAIMKMAKEAGVEVVT------ENSHTLYDLDRIIELN 160 T Y ++ I ++ + + + ++++ R I L Sbjct: 284 STTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDAVVHEIQRFITLV 343 Query: 161 GQKPPLTYKRFQALISRMELPKKPAVAVSSQQMESCRAEIQENHDDTYGVPS---LEELG 217 P ++ + I R L K V V + S + QE D P E Sbjct: 344 PSNLP--HEATRDTIFRGYLIPKGTVVVPTLD--SVLYDNQEFPDPEKFKPEHFLNENGK 399 Query: 218 FPTEGLGPAVWQGGET----EALARLDKHLERKAWVANYERPRMNANSLLASPTGLSP-Y 272 F + G+ E LAR++ L A + ++ + + LSP + Sbjct: 400 FKYSDYFKP-FSTGKRVCAGEGLARMELFLLLCAILQHFNLKPLVDPKDID----LSPIH 454 Query: 273 LRFGCLSCRL 282 + FGC+ R Sbjct: 455 IGFGCIPPRY 464 >5GAM-A nrPDB Length = 735 Score = 33.6 bits (75), Expect = 0.27, Method: Composition-based stats. Identities = 32/210 (15%), Positives = 62/210 (29%), Gaps = 39/210 (18%) Query: 143 VTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRMELPKKPAVAVSSQQMESCRAEIQE 202 + T + R + +PPL+Y++ I ++ P + + ++ + + Sbjct: 226 REKRDRTHFKRMRFPPFDDDEPPLSYEQHIENIEPLDPINLPLDSQDDEYVKDWLYDSRP 285 Query: 203 NHDDTYGV--PSLEELGFPTEGLGPAVWQGGETEALARLDKHLERKAWVANYER------ 254 +D+ V S ++ F E L RL L + NY Sbjct: 286 LEEDSKKVNGTSYKKWSFDLP----------EMSNLYRLSTPLRDEVTDKNYYYLFDKKS 335 Query: 255 --PRMNANSLLASPTGLSPYLRFGCLSCRLFYYRLWDLYKKVKRNSTPPLSLFGQLLWRE 312 N+ + P L R + ++ +F + E Sbjct: 336 FFNGKALNNAIPGGPKFEP------LYPRE-------EEEDYNEFNSIDRVIFRVPIRSE 382 Query: 313 FFYTAATNNPRFDRMEGNPICIQIPWDRNP 342 + P P ++IPW NP Sbjct: 383 Y----KVAFPHLY--NSRPRSVRIPWYNNP 406 >2X0P-A nrPDB Length = 618 Score = 32.8 bits (73), Expect = 0.40, Method: Composition-based stats. Identities = 22/119 (18%), Positives = 42/119 (35%), Gaps = 8/119 (6%) Query: 231 GETEALAR--LDKHLERKAWVANYERPRMNANSLLASPTGLSPYLRFGCLSCRLFYYRLW 288 GE + LA+ + Y + ++ ++ GLSPY G + + + L Sbjct: 275 GEEQYLAQQSIRTFFNISRPGKRYVKTSLSILNM-GFMRGLSPYYMAGTPAINEYIHDLI 333 Query: 289 DLYKKVKRNSTPPLSLFGQLLWREFFYTAATNNPRFDRMEGNPICIQIPWDRNPEALAK 347 ++ N L + +R ++Y AA + + + W NP L Sbjct: 334 SADPWLRANGFRILREVASMGFRNYYYEAAIDT----DTPYKKMFSAL-WRENPLTLIA 387 >6D97-A nrPDB Length = 547 Score = 32.5 bits (72), Expect = 0.55, Method: Composition-based stats. Identities = 12/67 (17%), Positives = 25/67 (37%), Gaps = 10/67 (14%) Query: 404 LDADFSVNAGSWMWLSCSAFFQQFFHCYCPVGFGRRTDPSGDYIRRYLPKLKGFPSRYIY 463 + ++ +A +W W+ +F + G I+ ++ L P ++ Sbjct: 49 VQGSWTASA-NWNWIVDPLNGDKFIKVA---------EVQGTEIKSFMESLSKCPKHGLH 98 Query: 464 EPWNAPE 470 P APE Sbjct: 99 NPLKAPE 105 >5M99-B nrPDB Length = 505 Score = 32.5 bits (72), Expect = 0.55, Method: Composition-based stats. Identities = 21/124 (16%), Positives = 34/124 (27%), Gaps = 21/124 (16%) Query: 319 TNNPRFDRMEGNPICIQIPWDRNPEALAKWAEGKTGFPWIDAIMTQLRQEGWIHHLARHA 378 + G W N + W G G+ M L + R Sbjct: 121 YYIMSLEDHSGQDHWH---WKINSKGQKVWYFGLFGY-----NMPDLNHD---SQKVREE 169 Query: 379 VACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSCSAFFQQFFHCYCPVGFGR 438 V + D W+S GV F D + + W W ++F + + Sbjct: 170 VKKIV---DFWIS--KGVDGFR-----IDAAKHIYGWSWDDGIQESAEYFEWFRDYVLSK 219 Query: 439 RTDP 442 + D Sbjct: 220 KPDA 223 >3LGB-A nrPDB Length = 194 Score = 31.3 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 15/49 (30%), Positives = 20/49 (40%), Gaps = 1/49 (2%) Query: 472 VQKAAKCIIGVDYPRPIVNHAETSRLNIERMKQIYQQLSRY-RGLCLLA 519 Q I +YP I N E + N QQLS + +G+ L A Sbjct: 6 AQSVWSEEISSNYPLCIKNLMEGLKKNHHLRYYGRQQLSLFLKGIGLSA 54 >3QR1-A nrPDB Length = 813 Score = 30.1 bits (66), Expect = 2.6, Method: Composition-based stats. Identities = 13/38 (34%), Positives = 17/38 (44%) Query: 378 AVACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSW 415 V L +GD ++ WE G F E+LL D W Sbjct: 17 NVPEQLIKGDKFLKWEEGSSSFTEILLRVDPKGYFLYW 54 >1KB0-A nrPDB Length = 677 Score = 29.8 bits (65), Expect = 3.3, Method: Composition-based stats. Identities = 11/53 (20%), Positives = 14/53 (26%), Gaps = 1/53 (1%) Query: 395 GVRV-FDELLLDADFSVNAGSWMWLSCSAFFQQFFHCYCPVGFGRRTDPSGDY 446 G + D W W S + F R DPSG + Sbjct: 183 GAEYGVRGYITAYDAETGERKWRWFSVPGDPSKPFEDESMKRAARTWDPSGKW 235 >4YZZ-A nrPDB Length = 367 Score = 29.8 bits (65), Expect = 3.7, Method: Composition-based stats. Identities = 13/66 (19%), Positives = 23/66 (34%), Gaps = 2/66 (3%) Query: 185 AVAVSSQQMESCRAEIQENHDDTYGVPSLEELGFPTEGLGPAVWQGGETEALARLDKHLE 244 + + + + + G E+LGF + P + G E A + + Sbjct: 194 PQQIPPGDIYPALEKGTIDAAEWIGPYDDEKLGF--NKVAPYYYSPGWFEGSASITSMVN 251 Query: 245 RKAWVA 250 KAW A Sbjct: 252 DKAWEA 257 >4NUR-A nrPDB Length = 633 Score = 29.0 bits (63), Expect = 5.6, Method: Composition-based stats. Identities = 17/117 (14%), Positives = 43/117 (36%), Gaps = 7/117 (5%) Query: 68 NRWRFLLQSLE------DLDTSLRKLNSRLFVVRGQPADVFPRLFKEWGVTRLTFEYDSE 121 R ++ +L L L S V P D+ + + LT+E+ Sbjct: 199 RRASYMYGNLLPPDAKGQLGAGLGTTTSAGTVTLIPPTDIIKETGETHVIDGLTYEFMYA 258 Query: 122 PFGKERDAAIMKMAKEAGVEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRM 178 P + + + ++ + +++HTL++ + + PL + ++ ++ Sbjct: 259 PGSEAPAEMLYYIKEKKALNAAEDSTHTLHNTYSLRGAKIRD-PLAWSKYLNEALKL 314 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.124 0.338 Lambda K H 0.267 0.0380 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 21,750,085 Number of Sequences: 36641 Number of extensions: 868384 Number of successful extensions: 2273 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 33 Number of HSP's successfully gapped in prelim test: 16 Number of HSP's that attempted gapping in prelim test: 2099 Number of HSP's gapped (non-prelim): 65 length of query: 592 length of database: 10,336,785 effective HSP length: 103 effective length of query: 489 effective length of database: 6,562,762 effective search space: 3209190618 effective search space used: 3209190618 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 62 (28.6 bits)