BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9R186 (767 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6E2G-A nrPDB 1508 0.0 6BOA-A nrPDB 1333 0.0 6DMR-A nrPDB 1080 0.0 2RFA-A nrPDB 451 e-127 6BBJ-A nrPDB 276 2e-74 6C8G-A nrPDB 275 6e-74 5IRX-A nrPDB 249 3e-66 6DVZ-A nrPDB 246 4e-65 6MHW-A nrPDB 238 5e-63 5AN8-A nrPDB 201 7e-52 6OO7-A nrPDB 192 7e-49 5HI9-A nrPDB 186 2e-47 6BO5-A nrPDB 186 3e-47 2ETB-A nrPDB 111 1e-24 3W9G-A nrPDB 108 1e-23 2NYJ-A nrPDB 108 1e-23 4DX2-A nrPDB 107 2e-23 4N5Q-A nrPDB 104 1e-22 2F37-A nrPDB 104 2e-22 5MIO-C nrPDB 72 1e-12 6MWQ-A nrPDB 70 4e-12 6FES-A nrPDB 61 2e-09 6AUN-A nrPDB 60 3e-09 5AQA-A nrPDB 59 1e-08 5AQ7-A nrPDB 57 3e-08 5AQB-A nrPDB 57 4e-08 3B7B-A nrPDB 52 1e-06 5AQ9-A nrPDB 49 6e-06 6BY9-A nrPDB 49 7e-06 5H76-A nrPDB 48 2e-05 5CBO-A nrPDB 48 2e-05 4NIK-A nrPDB 45 1e-04 4Z68-A nrPDB 45 1e-04 5GP7-A nrPDB 44 2e-04 4OAU-C nrPDB 44 4e-04 6G1K-A nrPDB 43 6e-04 4O1O-A nrPDB 42 0.001 6BWF-A nrPDB 41 0.003 5Z96-A nrPDB 40 0.003 5DND-A nrPDB 40 0.003 4OT9-A nrPDB 40 0.004 3EU9-A nrPDB 40 0.005 5HKP-A nrPDB 39 0.009 1BLX-B nrPDB 38 0.014 1BD8-A nrPDB 38 0.015 6CUD-A nrPDB 38 0.015 2DWZ-A nrPDB 38 0.018 6BPQ-A nrPDB 37 0.026 5JHQ-A nrPDB 37 0.032 5ET1-A nrPDB 37 0.039 3UI2-A nrPDB 36 0.063 6CV9-A nrPDB 34 0.19 3LJN-A nrPDB 34 0.24 3DEO-A nrPDB 33 0.54 2KXP-C nrPDB 33 0.56 3ZKJ-A nrPDB 33 0.68 1WG0-A nrPDB 32 1.2 6AYG-A nrPDB 32 1.3 3LVQ-E nrPDB 31 1.9 1G3N-B nrPDB 31 1.9 5MKE-A nrPDB 31 2.1 2B0O-E nrPDB 30 3.3 6DU8-A nrPDB 30 4.9 5U0K-A nrPDB 30 5.6 5UIL-A nrPDB 29 5.9 5UQE-A nrPDB 29 8.2 6BWI-A nrPDB 29 8.3 >6E2G-A nrPDB Length = 727 Score = 1508 bits (3903), Expect = 0.0, Method: Compositional matrix adjust. Identities = 727/727 (100%), Positives = 727/727 (100%) Query: 41 MGWSLPKEKGLILCLWNKFCRWFHRRESWAQSRDEQNLLQQKRIWESPLLLAAKENNVQA 100 MGWSLPKEKGLILCLWNKFCRWFHRRESWAQSRDEQNLLQQKRIWESPLLLAAKENNVQA Sbjct: 1 MGWSLPKEKGLILCLWNKFCRWFHRRESWAQSRDEQNLLQQKRIWESPLLLAAKENNVQA 60 Query: 101 LIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTA 160 LIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTA Sbjct: 61 LIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTA 120 Query: 161 LHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVR 220 LHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVR Sbjct: 121 LHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVR 180 Query: 221 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGL 280 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGL Sbjct: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGL 240 Query: 281 TPFKLAGVEGNIVMFQHLMQKRKHIQWTYGPLTSTLYDLTEIDSSGDDQSLLELIVTTKK 340 TPFKLAGVEGNIVMFQHLMQKRKHIQWTYGPLTSTLYDLTEIDSSGDDQSLLELIVTTKK Sbjct: 241 TPFKLAGVEGNIVMFQHLMQKRKHIQWTYGPLTSTLYDLTEIDSSGDDQSLLELIVTTKK 300 Query: 341 REARQILDQTPVKELVSLKWKRYGRPYFCVLGAIYVLYIICFTMCCVYRPLKPRITNRTN 400 REARQILDQTPVKELVSLKWKRYGRPYFCVLGAIYVLYIICFTMCCVYRPLKPRITNRTN Sbjct: 301 REARQILDQTPVKELVSLKWKRYGRPYFCVLGAIYVLYIICFTMCCVYRPLKPRITNRTN 360 Query: 401 PRDNTLLQQKLLQEAYVTPKDDLRLVGELVSIVGAVIILLVEIPDIFRLGVTRFFGQTIL 460 PRDNTLLQQKLLQEAYVTPKDDLRLVGELVSIVGAVIILLVEIPDIFRLGVTRFFGQTIL Sbjct: 361 PRDNTLLQQKLLQEAYVTPKDDLRLVGELVSIVGAVIILLVEIPDIFRLGVTRFFGQTIL 420 Query: 461 GGPFHVIIVTYAFMVLVTMVMRLTNSDGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIM 520 GGPFHVIIVTYAFMVLVTMVMRLTNSDGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIM Sbjct: 421 GGPFHVIIVTYAFMVLVTMVMRLTNSDGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIM 480 Query: 521 IQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPDELGHFYDYPMALFSTFELFLTII 580 IQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPDELGHFYDYPMALFSTFELFLTII Sbjct: 481 IQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPDELGHFYDYPMALFSTFELFLTII 540 Query: 581 DGPANYDVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQVVATT 640 DGPANYDVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQVVATT Sbjct: 541 DGPANYDVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQVVATT 600 Query: 641 VMLERKLPRCLWPRSGICGREYGLGDRWFLRVEDRQDLNRQRIRRYAQAFQQQDDLYSED 700 VMLERKLPRCLWPRSGICGREYGLGDRWFLRVEDRQDLNRQRIRRYAQAFQQQDDLYSED Sbjct: 601 VMLERKLPRCLWPRSGICGREYGLGDRWFLRVEDRQDLNRQRIRRYAQAFQQQDDLYSED 660 Query: 701 LEKDSGEKLEMARPFGAYLSFPTPSVSRSTSRSSTNWDRLRQGALRKDLQGIINRGLEDG 760 LEKDSGEKLEMARPFGAYLSFPTPSVSRSTSRSSTNWDRLRQGALRKDLQGIINRGLEDG Sbjct: 661 LEKDSGEKLEMARPFGAYLSFPTPSVSRSTSRSSTNWDRLRQGALRKDLQGIINRGLEDG 720 Query: 761 EGWEYQI 767 EGWEYQI Sbjct: 721 EGWEYQI 727 >6BOA-A nrPDB Length = 742 Score = 1333 bits (3450), Expect = 0.0, Method: Compositional matrix adjust. Identities = 649/728 (89%), Positives = 691/728 (94%), Gaps = 4/728 (0%) Query: 41 MGWSLPKEKGLILCLWNKFCRWFHRRESWAQSRDEQNLLQQKRIWESPLLLAAKENNVQA 100 MG SLPKEKGLILCLW+KFCRWF RRESWAQSRDEQNLLQQKRIWESPLLLAAK+N+VQA Sbjct: 1 MGLSLPKEKGLILCLWSKFCRWFQRRESWAQSRDEQNLLQQKRIWESPLLLAAKDNDVQA 60 Query: 101 LIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTA 160 L KLLK+E C+VHQ+GAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTA Sbjct: 61 LNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTA 120 Query: 161 LHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVR 220 LHIAV+NQN+NLVRALLAR ASVSARATG+ F P NLIY+GEHPLSFAACV SEEIVR Sbjct: 121 LHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVR 180 Query: 221 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD-GGDHLKSLELVPNNQG 279 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD GDHL+ L+LVPN+QG Sbjct: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQG 240 Query: 280 LTPFKLAGVEGNIVMFQHLMQKRKHIQWTYGPLTSTLYDLTEIDSSGDDQSLLELIVTTK 339 LTPFKLAGVEGN VMFQHLMQKRKH QWTYGPLTSTLYDLTEIDSSGD+QSLLELI+TTK Sbjct: 241 LTPFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEIDSSGDEQSLLELIITTK 300 Query: 340 KREARQILDQTPVKELVSLKWKRYGRPYFCVLGAIYVLYIICFTMCCVYRPLKPRITNRT 399 KREARQILDQTPVKELVSLKWKRYGRPYFC+LGAIY+LYIICFTMCC+YRPLKPR NRT Sbjct: 301 KREARQILDQTPVKELVSLKWKRYGRPYFCMLGAIYLLYIICFTMCCIYRPLKPRTNNRT 360 Query: 400 NPRDNTLLQQKLLQEAYVTPKDDLRLVGELVSIVGAVIILLVEIPDIFRLGVTRFFGQTI 459 +PRDNTLLQQKLLQEAY+TPKDD+RLVGELV+++GA+IILLVE+PDIFR+GVTRFFGQTI Sbjct: 361 SPRDNTLLQQKLLQEAYMTPKDDIRLVGELVTVIGAIIILLVEVPDIFRMGVTRFFGQTI 420 Query: 460 LGGPFHVIIVTYAFMVLVTMVMRLTNSDGEVVPMSFALVLGWCNVMYFARGFQMLGPFTI 519 LGGPFHV+I+TYAFMVLVTMVMRL ++ GEVVPMSFALVLGWCNVMYFA GFQMLGPFTI Sbjct: 421 LGGPFHVLIITYAFMVLVTMVMRLISASGEVVPMSFALVLGWCNVMYFAEGFQMLGPFTI 480 Query: 520 MIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPDELGHFYDYPMALFSTFELFLTI 579 MIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDP+ELGHFYDYPMALFSTFELFLTI Sbjct: 481 MIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPEELGHFYDYPMALFSTFELFLTI 540 Query: 580 IDGPANYDVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQVVAT 639 IDGPANY+VDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQ+VAT Sbjct: 541 IDGPANYNVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVAT 600 Query: 640 TVMLERKLPRCLWPRSGICGREYGLGDRWFLRVEDRQDLNRQRIRRYAQAFQQQDDLYSE 699 TVMLERKLPRCLWPRSGICGREYGLGDRWFLRVEDRQDLNRQRI+RYAQAF + SE Sbjct: 601 TVMLERKLPRCLWPRSGICGREYGLGDRWFLRVEDRQDLNRQRIQRYAQAFHTRG---SE 657 Query: 700 DLEKDSGEKLEMARPFGAYLSFPTPSVSRSTSRSSTNWDRLRQGALRKDLQGIINRGLED 759 DL+KDS EKLE+ PF +LS P PSVSRSTSRSS NW+RLRQG LR+DL+GIINRGLED Sbjct: 658 DLDKDSVEKLELGCPFSPHLSLPMPSVSRSTSRSSANWERLRQGTLRRDLRGIINRGLED 717 Query: 760 GEGWEYQI 767 GE WEYQI Sbjct: 718 GESWEYQI 725 >6DMR-A nrPDB Length = 730 Score = 1080 bits (2792), Expect = 0.0, Method: Compositional matrix adjust. Identities = 541/734 (73%), Positives = 610/734 (83%), Gaps = 24/734 (3%) Query: 41 MGWSLPKEKGLILCLWNKFCRWFHRRESWAQSRDEQNLLQQKRIWESPLLLAAKENNVQA 100 MG PK KG L W + W Q RD N+LQQ+RI +SPLL AAKEN+++ Sbjct: 1 MGACPPKAKGPWAQLQKLLISWPVGEQDWEQYRDRVNMLQQERIRDSPLLQAAKENDLRL 60 Query: 101 LIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTA 160 L LL + C+ Q+GA+GETALH+AALYDNLEAA +LMEAAPEL EP E + GQTA Sbjct: 61 LKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTA 120 Query: 161 LHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVR 220 LHIAV+NQN+NLVRALLARGASVSARATG+ F PHNLIYYGEHPLSFAACVGSEEIVR Sbjct: 121 LHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVR 180 Query: 221 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD-GGDHLKSLELVPNNQG 279 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD DHL+SLELVPN+QG Sbjct: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQG 240 Query: 280 LTPFKLAGVEGNIVMFQHLMQKRKHIQWTYGPLTSTLYDLTEIDSSGDDQSLLELIVTTK 339 LTPFKLAGVEGN VMFQHLMQKRKH+QWT GPLTSTLYDLTEIDS G++ S LEL+V++K Sbjct: 241 LTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSWGEELSFLELVVSSK 300 Query: 340 KREARQILDQTPVKELVSLKWKRYGRPYFCVLGAIYVLYIICFTMCCVYRPLKPRITNRT 399 KREARQIL+QTPVKELVS KWK+YGRPYFCVL ++Y+LY+ICFT CC+YRPLK R NRT Sbjct: 301 KREARQILEQTPVKELVSFKWKKYGRPYFCVLASLYILYMICFTTCCIYRPLKLRDDNRT 360 Query: 400 NPRDNTLLQQKLLQEAYVTPKDDLRLVGELVSIVGAVIILLVEIPDIFRLGVTRFFGQTI 459 +PRD T+LQQKLLQEAYVT +D++RLVGELV++ GAVIILL+EIPDIFR+G +R+FGQTI Sbjct: 361 DPRDITILQQKLLQEAYVTHQDNIRLVGELVTVTGAVIILLLEIPDIFRVGASRYFGQTI 420 Query: 460 LGGPFHVIIVTYAFMVLVTMVMRLTNSDGEVVPMSFALVLGWCNVMYFARGFQMLGPFTI 519 LGGPFHVII+TYA +VL+TMVMRLTN +GEVVP+SFALVLGWC+VMYFARGFQMLGPFTI Sbjct: 421 LGGPFHVIIITYASLVLLTMVMRLTNMNGEVVPLSFALVLGWCSVMYFARGFQMLGPFTI 480 Query: 520 MIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPDELGHFYDYPMALFSTFELFLTI 579 MIQKMIFGDLMRFCWLMAVVILGFASAF+I FQTEDP+ LG F DYP ALFSTFELFLTI Sbjct: 481 MIQKMIFGDLMRFCWLMAVVILGFASAFHITFQTEDPNNLGEFSDYPTALFSTFELFLTI 540 Query: 580 IDGPANYDVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQVVAT 639 IDGPANY VDLPFMY ITYAAFAIIATLLMLNL IAMMGDTHWRVA ERDELWRAQVVAT Sbjct: 541 IDGPANYSVDLPFMYCITYAAFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVAT 600 Query: 640 TVMLERKLPRCLWPRSGICGREYGLGDRWFLRVEDRQDLNRQRIRRYAQAFQQQDDLYSE 699 TVMLERK+PR LWPRSGICG EYGLGDRWFLRVE+ D N R+ RY +AF+ D Sbjct: 601 TVMLERKMPRFLWPRSGICGYEYGLGDRWFLRVENHHDQNPLRVLRYVEAFKCSD----- 655 Query: 700 DLEKDSGEKLEMARPFG--------AYLSFPTPSVSRSTSRSSTN---WDRLRQGALRKD 748 ++D E+L RP A ++F TPS+SR+TS+SS + W+ LR+ L Sbjct: 656 --KEDGQEQLSEKRPSTVESGMLSRASVAFQTPSLSRTTSQSSNSHRGWEILRRNTL--- 710 Query: 749 LQGIINRGLEDGEG 762 G +N GL+ GEG Sbjct: 711 --GHLNLGLDLGEG 722 >2RFA-A nrPDB Length = 232 Score = 451 bits (1160), Expect = e-127, Method: Compositional matrix adjust. Identities = 219/226 (96%), Positives = 222/226 (98%) Query: 84 IWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAP 143 IWESPLLLAAKEN+VQAL KLLKFEGCEVHQ+GAMGETALHIAALYDNLEAAMVLMEAAP Sbjct: 2 IWESPLLLAAKENDVQALSKLLKFEGCEVHQRGAMGETALHIAALYDNLEAAMVLMEAAP 61 Query: 144 ELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYG 203 ELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYG Sbjct: 62 ELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYG 121 Query: 204 EHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD 263 EHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD Sbjct: 122 EHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD 181 Query: 264 GGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKRKHIQWTY 309 GGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKRKHI + Sbjct: 182 GGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKRKHIAAAH 227 >6BBJ-A nrPDB Length = 868 Score = 276 bits (707), Expect = 2e-74, Method: Compositional matrix adjust. Identities = 190/584 (32%), Positives = 294/584 (50%), Gaps = 79/584 (13%) Query: 144 ELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHN-LIYY 202 E + P Y GQTALHIA+ + + V L+ +GA V A+A G F + Y+ Sbjct: 221 EFINSPFRDVYYRGQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYF 280 Query: 203 GEHPLSFAACVGSEEIVRLLIEHG---ADIRAQDSLGNTVLHILI-----LQPNKTFACQ 254 GE PLS AAC +IV L E+ ADIR QDS GNTVLH L+ + N F + Sbjct: 281 GELPLSLAACTNQPDIVHYLTENAHKKADIRRQDSRGNTVLHALVAIADNTRENTKFVTK 340 Query: 255 MYNLL------LSYDGGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQ-------- 300 +Y+LL L D SLE + NN ++P +A G I +FQH+++ Sbjct: 341 VYDLLVIKCVKLYPDS-----SLEAIFNNDSMSPLMMAAKLGKIGIFQHIIRLEIKDEEA 395 Query: 301 ---KRKHIQWTYGPLTSTLYDLTEIDSSGDDQSLLELIVTTKKREAR-QILDQTPVKELV 356 RK W YGP+ S+LYDL+ +D+ G++ S+LE++V K E R ++L P+ EL+ Sbjct: 396 RHLSRKFRDWAYGPVYSSLYDLSMLDTCGEEVSVLEILVYNSKVENRHEMLAVEPINELL 455 Query: 357 SLKWKRYGRPYFCVLGAIYVLYIICFTMCCVYRPLKPRITNRTNPRDNTLLQQKLLQEAY 416 KW+++G F + Y++ +I FT+ YRP+ + T P Y Sbjct: 456 RDKWQKFGAVSFYISVVSYLIAMIIFTLIAYYRPM-----DGTPPY------------PY 498 Query: 417 VTPKDDLRLVGELVSIVGAVIILLVEIPDIFRL---GVTRFFGQTILGGPFHVIIVTYAF 473 T D +RL GE+V+++ V+ + I D+F GV F + G F ++ Y+ Sbjct: 499 RTTMDYMRLAGEIVTLLTGVVFFITNIKDLFMKKCPGVNSLF----IDGSFQLLYFIYSV 554 Query: 474 MVLVTMVMRLTNSDGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFC 533 +V++T V+ L + + M FALVLGW N +YF RG ++ G ++IM+QK++F DL RF Sbjct: 555 LVIITAVLYLVGIESYLAVMVFALVLGWMNALYFTRGLKLTGTYSIMLQKILFKDLFRFL 614 Query: 534 WLMAVVILGFASAFYIIFQTEDPDEL-------GHFYDYPMA---------LFSTFELFL 577 + + ++G+ASA + E +YP L F+L + Sbjct: 615 LVYLLFMIGYASALVSLLNPCTSQESCIETSSNCTVPEYPSCRDSSTFSKFLLDLFKLTI 674 Query: 578 TIIDGPANYDVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQVV 637 + D P ++ I + I+ +L+LN+LIA+MG+T +V+ E ++W+ Q Sbjct: 675 GMGDLEMINSAKYPAVFIILLVTYIILTFVLLLNMLIALMGETVGQVSKESKQIWKLQWA 734 Query: 638 ATTVMLERKLPRCLWP--RSG---ICGREY-GLGD-RWFLRVED 674 T + +ER P C+ RSG G+ G D RW RV++ Sbjct: 735 TTILDIERSFPVCMRKAFRSGEMVTVGKNLDGTPDRRWCFRVDE 778 >6C8G-A nrPDB Length = 675 Score = 275 bits (702), Expect = 6e-74, Method: Compositional matrix adjust. Identities = 188/579 (32%), Positives = 294/579 (50%), Gaps = 69/579 (11%) Query: 144 ELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHN-LIYY 202 E + P Y GQTALHIA+ + + V L+ +GA V A+A G F + Y+ Sbjct: 90 EFINSPFRDVYYRGQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYF 149 Query: 203 GEHPLSFAACVGSEEIVRLLIEHG---ADIRAQDSLGNTVLHILI-----LQPNKTFACQ 254 GE PLS AAC +IV L E+ ADIR QDS GNTVLH L+ + N F + Sbjct: 150 GELPLSLAACTNQPDIVHYLTENAHKKADIRRQDSRGNTVLHALVAIADNTRENTKFVTK 209 Query: 255 MYNLLLSYDGGDHL-KSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQ-----------KR 302 +Y+LL+ + SLE + NN ++P +A G I +FQH+++ R Sbjct: 210 VYDLLVIKCVKLYPDSSLEAIFNNDSMSPLMMAAKLGKIGIFQHIIRLEIKDEEARHLSR 269 Query: 303 KHIQWTYGPLTSTLYDLTEIDSSGDDQSLLELIVTTKKREAR-QILDQTPVKELVSLKWK 361 K W YGP+ S+LYDL+ +D+ G++ S+LE++V K E R ++L P+ EL+ KW+ Sbjct: 270 KFRDWAYGPVYSSLYDLSMLDTCGEEVSVLEILVYNSKVENRHEMLAVEPINELLRDKWQ 329 Query: 362 RYGRPYFCVLGAIYVLYIICFTMCCVYRPLKPRITNRTNPRDNTLLQQKLLQEAYVTPKD 421 ++G F + Y++ +I FT+ YRP+ + T P Y T D Sbjct: 330 KFGAVSFYISVVSYLIAMIIFTLIAYYRPM-----DGTPPY------------PYRTTMD 372 Query: 422 DLRLVGELVSIVGAVIILLVEIPDIFRL---GVTRFFGQTILGGPFHVIIVTYAFMVLVT 478 +RL GE+V+++ V+ + I D+F GV F + G F ++ Y+ +V++T Sbjct: 373 YMRLAGEIVTLLTGVVFFITNIKDLFMKKCPGVNSLF----IDGSFQLLYFIYSVLVIIT 428 Query: 479 MVMRLTNSDGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAV 538 V+ L + + M FALVLGW N +YF RG ++ G ++IM+QK++F DL RF + + Sbjct: 429 AVLYLVGIESYLAVMVFALVLGWMNALYFTRGLKLTGTYSIMLQKILFKDLFRFLLVYLL 488 Query: 539 VILGFASAFYIIFQTEDPDEL-------GHFYDYPMA---------LFSTFELFLTIIDG 582 ++G+ASA + E +YP L F+L + + D Sbjct: 489 FMIGYASALVSLLNPCTSQESCIETSSQCTVPEYPSCRDSSTFSKFLLDLFKLTIGMGDL 548 Query: 583 PANYDVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQVVATTVM 642 P ++ I + I+ +L+LN+LIA+MG+T +V+ E ++W+ Q T + Sbjct: 549 EMINSAKYPAVFIILLVTYIILTFVLLLNMLIALMGETVGQVSKESKQIWKLQWATTILD 608 Query: 643 LERKLPRCLWP--RSG---ICGREY-GLGD-RWFLRVED 674 +ER P C+ RSG G+ G D RW RV++ Sbjct: 609 IERSFPVCMRKAFRSGEMVTVGKNLDGTPDRRWCFRVDE 647 >5IRX-A nrPDB Length = 636 Score = 249 bits (636), Expect = 3e-66, Method: Compositional matrix adjust. Identities = 181/567 (31%), Positives = 281/567 (49%), Gaps = 59/567 (10%) Query: 140 EAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHY---RP 196 ++ + V T Y+GQTALHIA+ +N+ LV L+ GA V A A G F RP Sbjct: 79 DSLKQFVNASYTDSYYKGQTALHIAIERRNMTLVTLLVENGADVQAAANGDFFKKTKGRP 138 Query: 197 HNLIYYGEHPLSFAACVGSEEIVRLLIEHG---ADIRAQDSLGNTVLHILILQPNKT--- 250 Y+GE PLS AAC IV+ L+++ ADI A+DS+GNTVLH L+ + T Sbjct: 139 G--FYFGELPLSLAACTNQLAIVKFLLQNSWQPADISARDSVGNTVLHALVEVADNTVDN 196 Query: 251 --FACQMYNLLLSYDGGDH-LKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQK------ 301 F MYN +L H LE + N +GLTP LA G I + +++Q+ Sbjct: 197 TKFVTSMYNEILILGAKLHPTLKLEEITNRKGLTPLALAASSGKIGVLAYILQREIHEPE 256 Query: 302 -----RKHIQWTYGPLTSTLYDLTEIDSSGDDQSLLELIV--TTKKREARQILDQTPVKE 354 RK +W YGP+ S+LYDL+ ID+ + S+LE+I +++ +L P+ Sbjct: 257 CRHLSRKFTEWAYGPVHSSLYDLSCIDTC-EKNSVLEVIAYSSSETPNRHDMLLVEPLNR 315 Query: 355 LVSLKWKRYGRPYFCVLGAIYVLYIICFTMCCVYRPLKPRITNRTNPRDNTLLQQKLLQE 414 L+ KW R+ + F +Y LY+I FT YRP++ L KL Sbjct: 316 LLQDKWDRFVKRIFYFNFFVYCLYMIIFTAAAYYRPVEG------------LPPYKLKN- 362 Query: 415 AYVTPKDDLRLVGELVSIVGAVIILLVEIPDIFRLGVTRFFGQTILGGPFHVIIVTYAFM 474 T D R+ GE++S+ G V I + L + ++ + Sbjct: 363 ---TVGDYFRVTGEILSVSGGVYFFFRGIQ--YFLQRRPSLKSLFVDSYSEILFFVQSLF 417 Query: 475 VLVTMVMRLTNSDGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCW 534 +LV++V+ + V M F+L +GW N++Y+ RGFQ +G + +MI+KMI DL RF + Sbjct: 418 MLVSVVLYFSQRKEYVASMVFSLAMGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMF 477 Query: 535 LMAVVILGFASAFYIIFQTEDPDELGHFYDYPMALFSTFELFLTIIDGPANYDVDLPFMY 594 + V + GF++A ++ ED + Y + LF F + + ++ NYD F+ Sbjct: 478 VYLVFLFGFSTA--VVTLIED-GKYNSLYSTCLELFK-FTIGMGDLEFTENYDFKAVFI- 532 Query: 595 SITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQVVATTVMLERKLPRCLWP- 653 I A+ I+ +L+LN+LIA+MG+T ++A E +W+ Q T + E+ +C+ Sbjct: 533 -ILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAITILDTEKSFLKCMRKA 591 Query: 654 -RSG----ICGREYGLGD-RWFLRVED 674 RSG + G D RW RV++ Sbjct: 592 FRSGKLLQVGFTPDGKDDYRWCFRVDE 618 >6DVZ-A nrPDB Length = 791 Score = 246 bits (627), Expect = 4e-65, Method: Compositional matrix adjust. Identities = 164/527 (31%), Positives = 276/527 (52%), Gaps = 44/527 (8%) Query: 151 TSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYR-PHNLIYYGEHPLSF 209 T E YEGQTAL+IA+ + ++ L+A GA V+A A G F+ + H Y+GE PL+ Sbjct: 209 TEEAYEGQTALNIAIERRQGDITAVLIAAGADVNAHAKGVFFNPKYQHEGFYFGETPLAL 268 Query: 210 AACVGSEEIVRLLIEH-GADIRAQDSLGNTVLHILI-----LQPNKTFACQMYNLLLSYD 263 AAC EIV+LL+E+ DI +QDS GN +LH L+ + F +MY+++L Sbjct: 269 AACTNQPEIVQLLMENEQTDITSQDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILLRS 328 Query: 264 GGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQK-----------RKHIQWTYGPL 312 G L+++ NN GLTP +LA G + ++++ + RK W YGP+ Sbjct: 329 GNWELETMR---NNDGLTPLQLAAKMGKAEILKYILSREIKEKPLRSLSRKFTDWAYGPV 385 Query: 313 TSTLYDLTEIDSSGDDQSLLELIVTTKKREAR-QILDQTPVKELVSLKWKRYGRPYFCVL 371 +S+LYDLT +D++ D+ S+LE+IV + R ++L P+ L+ KWK++ + F + Sbjct: 386 SSSLYDLTNVDTTTDN-SVLEIIVYNTNIDNRHEMLTLEPLHTLLHTKWKKFAKYMFFLS 444 Query: 372 GAIYVLYIICFTMCCVYRPLKPRITNRTNPRDNTLLQQKLLQEAYVTPKDDLRLVGELVS 431 Y Y I T+ YR PR++ L L A L+L+G + Sbjct: 445 FCFYFFYNITLTLVSYYR-----------PREDEDLPHPL---ALTHKMSWLQLLGRMFV 490 Query: 432 IVGAVIILLVEIPDIFRLGVTRFFGQTILGGP-FHVIIVTYAFMVLVTMVMRLTNSDGEV 490 ++ A I + E IF L + Q+IL FH + A +V++++ + L + Sbjct: 491 LIWATCISVKEGIAIFLLRPSDL--QSILSDAWFHFVFFVQAVLVILSVFLYLFAYKEYL 548 Query: 491 VPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYII 550 + A+ LGW N++ + RGFQ +G +++MIQK+I D+++F ++ + +LGF A + Sbjct: 549 ACLVLAMALGWANMLAYTRGFQSMGMYSVMIQKVILHDVLKFLFVYILFLLGFGVALASL 608 Query: 551 FQ--TEDPDELGHFYDYPMALFSTFELFLTIIDGPANYDVDLPFMYSITYAAFAIIATLL 608 + ++D + + + A+ F+L + + D + P ++ + I+ +L Sbjct: 609 IEKCSKDKKDCSSYGSFSDAVLELFKLTIGLGDLNIQQNSTYPILFLFLLITYVILTFVL 668 Query: 609 MLNLLIAMMGDTHWRVAHERDELWRAQVVATTVMLERKLPRCLWPRS 655 +LN+LIA+MG+T V+ E + +WR Q T + E+ LP W RS Sbjct: 669 LLNMLIALMGETVENVSKESERIWRLQRARTILEFEKMLPE--WLRS 713 >6MHW-A nrPDB Length = 826 Score = 238 bits (608), Expect = 5e-63, Method: Compositional matrix adjust. Identities = 165/527 (31%), Positives = 275/527 (52%), Gaps = 44/527 (8%) Query: 151 TSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYR-PHNLIYYGEHPLSF 209 T E YEGQTAL+IA+ + ++ L+A GA V+A A G+ F+ + H Y+GE PL+ Sbjct: 210 TEEAYEGQTALNIAIERRQGDIAALLIAAGADVNAHAKGAFFNPKYQHEGFYFGETPLAL 269 Query: 210 AACVGSEEIVRLLIEH-GADIRAQDSLGNTVLHILI-----LQPNKTFACQMYNLLLSYD 263 AAC EIV+LL+EH DI ++DS GN +LH L+ + F +MY+++L Sbjct: 270 AACTNQPEIVQLLMEHEQTDITSRDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILLRS 329 Query: 264 GGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQK-----------RKHIQWTYGPL 312 G LE NN GLTP +LA G + ++++ + RK W YGP+ Sbjct: 330 GN---WELETTRNNDGLTPLQLAAKMGKAEILKYILSREIKEKRLRSLSRKFTDWAYGPV 386 Query: 313 TSTLYDLTEIDSSGDDQSLLELIVTTKKREAR-QILDQTPVKELVSLKWKRYGRPYFCVL 371 +S+LYDLT +D++ D+ S+LE+ V + R ++L P+ L+ +KWK++ + F + Sbjct: 387 SSSLYDLTNVDTTTDN-SVLEITVYNTNIDNRHEMLTLEPLHTLLHMKWKKFAKHMFFLS 445 Query: 372 GAIYVLYIICFTMCCVYRPLKPRITNRTNPRDNTLLQQKLLQEAYVTPKDDLRLVGELVS 431 Y Y I T+ YR PR+ + L A L+L+G + Sbjct: 446 FCFYFFYNITLTLVSYYR-----------PREEEAIPHPL---ALTHKMGWLQLLGRMFV 491 Query: 432 IVGAVIILLVEIPDIFRLGVTRFFGQTILGGP-FHVIIVTYAFMVLVTMVMRLTNSDGEV 490 ++ A+ I + E IF L + Q+IL FH + A +V++++ + L + Sbjct: 492 LIWAMCISVKEGIAIFLLRPSDL--QSILSDAWFHFVFFIQAVLVILSVFLYLFAYKEYL 549 Query: 491 VPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYII 550 + A+ LGW N++Y+ RGFQ +G +++MIQK+I D+++F ++ V +LGF A + Sbjct: 550 ACLVLAMALGWANMLYYTRGFQSMGMYSVMIQKVILHDVLKFLFVYIVFLLGFGVALASL 609 Query: 551 FQT--EDPDELGHFYDYPMALFSTFELFLTIIDGPANYDVDLPFMYSITYAAFAIIATLL 608 + +D + + + A+ F+L + + D + P ++ + I+ +L Sbjct: 610 IEKCPKDNKDCSSYGSFSDAVLELFKLTIGLGDLNIQQNSKYPILFLFLLITYVILTFVL 669 Query: 609 MLNLLIAMMGDTHWRVAHERDELWRAQVVATTVMLERKLPRCLWPRS 655 +LN+LIA+MG+T V+ E + +WR Q T + E+ LP W RS Sbjct: 670 LLNMLIALMGETVENVSKESERIWRLQRARTILEFEKMLPE--WLRS 714 >5AN8-A nrPDB Length = 613 Score = 201 bits (512), Expect = 7e-52, Method: Compositional matrix adjust. Identities = 175/566 (30%), Positives = 291/566 (51%), Gaps = 58/566 (10%) Query: 113 HQKGAMGETALHIAAL--YDNLEAAMV-LME-----AAPE-LVFEPMTSELYEGQTALHI 163 + +G+ G+T L A L D + A + L+E P+ LV T E Y G +ALHI Sbjct: 34 YTEGSTGKTCLMKAVLNLQDGVNACIQPLLEIDRDSGNPQPLVNAQCTDEYYRGHSALHI 93 Query: 164 AVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLI 223 A+ +++ V+ L+ GA+V A+A G F Y+GE PLS AAC ++V L+ Sbjct: 94 AIEKRSLQCVKLLVENGANVHAKACGHFFQKNQDTCFYFGELPLSLAACTKQWDVVNYLL 153 Query: 224 EH---GADIRAQDSLGNTVLHILIL-----QPNKTFACQMYNLLLSYDGGDHL---KSLE 272 E+ A ++AQDSLGNTVLH L++ N +MY+ LL G L LE Sbjct: 154 ENPHPAASLQAQDSLGNTVLHALVMIADNSPENSALVVRMYDGLL--QAGARLCPNVQLE 211 Query: 273 LVPNNQGLTPFKLAGVEGNIVMFQHLMQK----------RKHIQWTYGPLTSTLYDLTEI 322 +PN +GLTP KLA EG I +F+H++Q+ RK +W YGP+ +LYDL + Sbjct: 212 GIPNLEGLTPLKLAAKEGKIEIFKHILQREFSAPCQSLSRKFTEWCYGPVRVSLYDLASV 271 Query: 323 DSSGDDQSLLELIVTTKKREAR-QILDQTPVKELVSLKWKRYGRPYFCVLGAIYVLYIIC 381 D S ++ S+LE+I + R +++ P+ +L+ KW R P FC Y++Y++ Sbjct: 272 D-SWEENSVLEIIAFHSRSPHRHRMVVLEPLNKLLQAKWDRL-IPRFCFNFLCYLVYMLI 329 Query: 382 FTMCCVYRPLKPRITNRTNPRDNTLLQQKLLQEAYVTPKDDLRLVGELVSIVGAVIILLV 441 FT ++P L+++ T + + L+G ++ ++G V +LL Sbjct: 330 FTAVAYHQP---------------ALEKQGFPPLKATAGNSMLLLGHILILLGGVYLLLG 374 Query: 442 EIPDIFRLGVTRFFGQTILGGPFHVIIVTYAFMVLVTMVMRLTNSDGEVVPMSFALVLGW 501 ++ +R + F + + F ++ + A + +++ V+ + + + +LVLGW Sbjct: 375 QLWYFWRRRL--FIWISFMDSYFEILFLLQALLTVLSQVLCFLAIEWYLPLLVSSLVLGW 432 Query: 502 CNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPDELGH 561 N++Y+ RGFQ G +++MIQK+I DL+RF + V + GFA A + + DE Sbjct: 433 LNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVSLSREAQEDEAP- 491 Query: 562 FYDYPMALFSTFELF-LTIIDGPANYDVDLPF--MYSITYAAFAIIATLLMLNLLIAMMG 618 Y L ++ ELF TI G + L F + + A+ ++ +L+LN+LIA+M Sbjct: 492 --PYRSILDASLELFKFTIGMGELAFQEQLRFRGVVLLLLLAYVLLTYVLLLNMLIALMS 549 Query: 619 DTHWRVAHERDELWRAQVVATTVMLE 644 +T VA + +W+ Q + + +E Sbjct: 550 ETVNSVATDSWSIWKLQKAISVLEME 575 >6OO7-A nrPDB Length = 786 Score = 192 bits (487), Expect = 7e-49, Method: Compositional matrix adjust. Identities = 171/583 (29%), Positives = 291/583 (49%), Gaps = 72/583 (12%) Query: 113 HQKGAMGETALHIAAL--YDNLEAAMV-LME-----AAPE-LVFEPMTSELYEGQTALHI 163 + +G+ G+T L A L D + A + L+E P+ LV T E Y G +ALHI Sbjct: 109 YTEGSTGKTCLMKAVLNLQDGVNACIQPLLEIDRDSGNPQPLVNAQCTDEYYRGHSALHI 168 Query: 164 AVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLI 223 A+ +++ V+ L+ GA+V A+A G F Y+GE PLS AAC ++V L+ Sbjct: 169 AIEKRSLQCVKLLVENGANVHAKACGHFFQKNQDTCFYFGELPLSLAACTKQWDVVNYLL 228 Query: 224 EH---GADIRAQDSLGNTVLHILIL-----QPNKTFACQMYNLLLSYDGGDHL---KSLE 272 E+ A ++AQDSLGNTVLH L++ N +MY+ LL G L LE Sbjct: 229 ENPHQPASLQAQDSLGNTVLHALVMIADDSAENSALVVRMYDGLL--QAGARLCPNVQLE 286 Query: 273 LVPNNQGLTPFKLAGVEGNIVMFQHLMQK----------RKHIQWTYGPLTSTLYDLTEI 322 +PN +GLTP KLA EG I +F+H++Q+ RK +W YGP+ +LYDL + Sbjct: 287 GIPNLEGLTPLKLAAKEGKIEIFKHILQREFSAPCQSLSRKFTEWCYGPVRVSLYDLASV 346 Query: 323 DSSGDDQSLLELIVTTKKREAR-QILDQTPVKELVSLKWKRYGRPYFCVLGAIYVLYIIC 381 D S ++ S+LE+I + R +++ P+ +L+ KW R P FC Y++Y++ Sbjct: 347 D-SWEENSVLEIIAFHSRSPHRHRMVVLEPLNKLLQAKWDRL-IPRFCFNFLCYLVYMLI 404 Query: 382 FTMCCVYRPLKPRITNRTNPRDNTLLQQKLLQEAYVTPKDDLRLVGELVSIVGAVIILLV 441 FT ++P L+++ T + + L+G ++ ++G V +LL Sbjct: 405 FTAVAYHQP---------------ALEKQGFPPLKATAGNSMLLLGHILILLGGVYLLLG 449 Query: 442 EIPDIFRLGVTRFFGQTILGGPFHVIIVTYAFMVLVTMVMRLTNSDGEVVPMSFALVLGW 501 ++ +R + F + + ++ + A + +++ V+ + + + +L +GW Sbjct: 450 QLWYFWRRRL--FIWISFMDSYSEILFLLQALLTVLSQVLCFLAIEWYLPLLVSSLAMGW 507 Query: 502 CNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTE------- 554 N++Y+ RGFQ G +++MI+K+I DL+RF + V + GFA A + + Sbjct: 508 TNLLYYTRGFQHTGIYSVMIEKVILRDLLRFLLVYLVFLFGFAVALVSLSREAQNSRTPA 567 Query: 555 --DPDELGH--------FYDYPMALFSTFELF-LTIIDGPANYDVDLPF--MYSITYAAF 601 + E+G Y L ++ ELF TI G + L F + + A+ Sbjct: 568 GPNATEVGQPGAGQEDEAPPYRSILDASLELFKFTIGMGELAFQEQLRFRGVVLLLLLAY 627 Query: 602 AIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQVVATTVMLE 644 ++ +L+LN+LIA+M +T VA + +W+ Q + + +E Sbjct: 628 VLLTYVLLLNMLIALMSETVNSVATDSWSIWKLQKAISVLEME 670 >5HI9-A nrPDB Length = 770 Score = 186 bits (473), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 186/622 (29%), Positives = 304/622 (48%), Gaps = 81/622 (13%) Query: 112 VHQKGAMGETALHIAAL--YDNLEAAMVLM------EAAPE-LVFEPMTSELYEGQTALH 162 + +G+ G+T L A L D + A ++ + P+ LV T E Y+G +ALH Sbjct: 110 AYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKPLVNAQCTDEFYQGHSALH 169 Query: 163 IAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLL 222 IA+ +++ V+ L+ GA V RA G F Y+GE PLS AAC ++V L Sbjct: 170 IAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYL 229 Query: 223 IEHG---ADIRAQDSLGNTVLHILIL-----QPNKTFACQMYNLLLSYDGGDHL---KSL 271 +E+ A + A DSLGNTVLH L++ N MY+ LL G L L Sbjct: 230 LENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQM--GARLCPTVQL 287 Query: 272 ELVPNNQGLTPFKLAGVEGNIVMFQHLMQK----------RKHIQWTYGPLTSTLYDLTE 321 E + N+QGLTP KLA EG I +F+H++Q+ RK +W YGP+ +LYDL+ Sbjct: 288 EEISNHQGLTPLKLAAKEGKIEIFRHILQREFSGPYQPLSRKFTEWCYGPVRVSLYDLSS 347 Query: 322 IDSSGDDQSLLELIVTTKKREAR-QILDQTPVKELVSLKWKRYGRPYFCVLGAIYVLYII 380 +DS + S+LE+I K R +++ P+ +L+ KW R +F A Y++Y+ Sbjct: 348 VDS-WEKNSVLEIIAFHCKSPNRHRMVVLEPLNKLLQEKWDRLVSRFFFNF-ACYLVYMF 405 Query: 381 CFTMCCVYRPLKPRITNRTNPRDNTLLQQKLLQEAYVTPKDDLRLVGELVSIVGAVIILL 440 FT+ ++P L Q + + T + + L+G ++ ++G + +LL Sbjct: 406 IFTVVAYHQPS---------------LDQPAIPSSKATFGESMLLLGHILILLGGIYLLL 450 Query: 441 VEIPDIFRLGVTRFFGQTILGGPFHVIIVTYAFMVLVTMVMRLTNSDGEVVPMSFALVLG 500 ++ +R + F + + F ++ + A + +++ V+R ++ + + +LVLG Sbjct: 451 GQLWYFWRRRL--FIWISFMDSYFEILFLLQALLTVLSQVLRFMETEWYLPLLVLSLVLG 508 Query: 501 WCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQ-------- 552 W N++Y+ RGFQ G +++MIQK+I DL+RF + V + GFA A + + Sbjct: 509 WLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVSLSREARSPKAP 568 Query: 553 -------TEDPDELGHFYD---YPMALFSTFELF-LTIIDGPANYDVDLPF--MYSITYA 599 TE P +G + Y L ++ ELF TI G + L F + + Sbjct: 569 EDNNSTVTEQPT-VGQEEEPAPYRSILDASLELFKFTIGMGELAFQEQLRFRGVVLLLLL 627 Query: 600 AFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQVVATTVMLERKLPRCLWP--RSG- 656 A+ ++ +L+LN+LIA+M +T VA +W+ Q + + +E C R G Sbjct: 628 AYVLLTYVLLLNMLIALMSETVNHVADNSWSIWKLQKAISVLEMENGYWWCRRKKHREGR 687 Query: 657 ---ICGREYGLGD-RWFLRVED 674 + R G D RW RVE+ Sbjct: 688 LLKVGTRGDGTPDERWCFRVEE 709 >6BO5-A nrPDB Length = 695 Score = 186 bits (472), Expect = 3e-47, Method: Compositional matrix adjust. Identities = 182/626 (29%), Positives = 297/626 (47%), Gaps = 89/626 (14%) Query: 112 VHQKGAMGETALHIAAL--YDNLEAA-MVLMEAAPE------LVFEPMTSELYEGQTALH 162 + +G+ G+T L A L D + A M L++ + LV T E Y+G +ALH Sbjct: 70 AYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKPLVNAQCTDEFYQGHSALH 129 Query: 163 IAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLL 222 IA+ +++ V+ L+ GA V RA G F Y+GE PLS AAC ++V L Sbjct: 130 IAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYL 189 Query: 223 IEHG---ADIRAQDSLGNTVLHILIL-----QPNKTFACQMYNLLLSYDGGDHL---KSL 271 +E+ A + A DSLGNTVLH L++ N MY+ LL G L L Sbjct: 190 LENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQM--GARLCPTVQL 247 Query: 272 ELVPNNQGLTPFKLAGVEGNIVMFQHLMQK----------RKHIQWTYGPLTSTLYDLTE 321 E + N+QGLTP KLA EG I +F+H++Q+ RK +W YGP+ +LYDL+ Sbjct: 248 EEISNHQGLTPLKLAAKEGKIEIFRHILQREFSGPYQPLSRKFTEWCYGPVRVSLYDLSS 307 Query: 322 IDSSGDDQSLLELIVTTKKREAR-QILDQTPVKELVSLKWKRYGRPYFCVLGAIYVLYII 380 +DS + S+LE+I K R +++ P+ +L+ KW R +F A Y++Y+ Sbjct: 308 VDS-WEKNSVLEIIAFHCKSPNRHRMVVLEPLNKLLQEKWDRLVSRFFFNF-ACYLVYMF 365 Query: 381 CFTMCCVYRPLKPRITNRTNPRDNTLLQQKLLQEAYVTPKDDLRLVGELVSIVGAVIILL 440 FT+ ++P L Q + + T + + L+G ++ ++G + +LL Sbjct: 366 IFTVVAYHQPS---------------LDQPAIPSSKATFGESMLLLGHILILLGGIYLLL 410 Query: 441 VEIPDIFRLGVTRFFGQTILGGPFHVIIVTYAFMVLVTMVMRLTNSDGEVVPMSFALVLG 500 ++ +R + F + + F ++ + A + +++ V+R ++ + + +LVLG Sbjct: 411 GQLWYFWRRRL--FIWISFMDSYFEILFLLQALLTVLSQVLRFMETEWYLPLLVLSLVLG 468 Query: 501 WCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFY------------ 548 W N++Y+ RGFQ G +++MIQK+I DL+RF + V + GFA A Sbjct: 469 WLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAVALVSLSREARSPKAP 528 Query: 549 -----------IIFQTEDPDELGHFYDYPMALFSTFELFLTIIDGPANYDVDLPF--MYS 595 + Q E+P D + LF TI G + L F + Sbjct: 529 EDNNSTVTEQPTVGQEEEPAPYRSILDASLELFK-----FTIGMGELAFQEQLRFRGVVL 583 Query: 596 ITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQVVATTVMLERKLPRCLWPRS 655 + A+ ++ +L+LN+LIA+M +T VA +W+ Q + + +E C + Sbjct: 584 LLLLAYVLLTYVLLLNMLIALMSETVNHVADNSWSIWKLQKAISVLEMENGYWWCRRKKH 643 Query: 656 ------GICGREYGLGD-RWFLRVED 674 + R G D RW RVE+ Sbjct: 644 REGRLLKVGTRGDGTPDERWCFRVEE 669 >2ETB-A nrPDB Length = 256 Score = 111 bits (277), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 78/211 (36%), Positives = 110/211 (52%), Gaps = 22/211 (10%) Query: 112 VHQKGAMGETALHIAAL--YDNLEAA-MVLMEAAPE------LVFEPMTSELYEGQTALH 162 + +G+ G+T L A L D + A M L++ + LV T E Y+G +ALH Sbjct: 36 AYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKPLVNAQCTDEFYQGHSALH 95 Query: 163 IAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLL 222 IA+ +++ V+ L+ GA V RA G F Y+GE PLS AAC ++V L Sbjct: 96 IAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYL 155 Query: 223 IEH---GADIRAQDSLGNTVLHILIL-----QPNKTFACQMYNLLLSYDGGDHL---KSL 271 +E+ A + A DSLGNTVLH L++ N MY+ LL G L L Sbjct: 156 LENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQM--GARLCPTVQL 213 Query: 272 ELVPNNQGLTPFKLAGVEGNIVMFQHLMQKR 302 E + N+QGLTP KLA EG I +F+H++Q+ Sbjct: 214 EEISNHQGLTPLKLAAKEGKIEIFRHILQRE 244 >3W9G-A nrPDB Length = 260 Score = 108 bits (269), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 68/175 (38%), Positives = 92/175 (52%), Gaps = 24/175 (13%) Query: 144 ELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPH-NLIYY 202 E + P Y GQTALHIA+ + + V L+ +GA V A+A G F + Y+ Sbjct: 80 EFINSPFRDVYYRGQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYF 139 Query: 203 GEHPLSFAACVGSEEIVRLLIEHG---ADIRAQDSLGNTVLHILI-----LQPNKTFACQ 254 GE PLS AAC IV L E+G AD+R QDS GNTVLH L+ + N F + Sbjct: 140 GELPLSLAACTNQPHIVHYLTENGHKQADLRRQDSRGNTVLHALVAIADNTRENTKFVTK 199 Query: 255 MYNLLLSYDGGDHLKSLELVP--------NNQGLTPFKLAGVEGNIVMFQHLMQK 301 MY+LLL +K +L P NN GL+P +A G I +FQH++++ Sbjct: 200 MYDLLL-------IKCAKLFPDTNLEALLNNDGLSPLMMAAKTGKIGIFQHIIRR 247 >2NYJ-A nrPDB Length = 273 Score = 108 bits (269), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 71/174 (40%), Positives = 94/174 (54%), Gaps = 16/174 (9%) Query: 144 ELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHY---RPHNLI 200 + V T Y+GQTALHIA+ +N+ LV L+ GA V A A G F RP Sbjct: 88 QFVNASYTDSYYKGQTALHIAIERRNMTLVTLLVENGADVQAAANGDFFKKTKGRPG--F 145 Query: 201 YYGEHPLSFAACVGSEEIVRLLIEHG---ADIRAQDSLGNTVLHILILQPNKT-----FA 252 Y+GE PLS AAC IV+ L+++ ADI A+DS+GNTVLH L+ + T F Sbjct: 146 YFGELPLSLAACTNQLAIVKFLLQNSWQPADISARDSVGNTVLHALVEVADNTVDNTKFV 205 Query: 253 CQMYNLLLSYDGGDH--LKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKRKH 304 MYN +L H LK LE + N +GLTP LA G I + +++Q+ H Sbjct: 206 TSMYNEILILGAKLHPTLK-LEEITNRKGLTPLALAASSGKIGVLAYILQREIH 258 >4DX2-A nrPDB Length = 259 Score = 107 bits (266), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 70/175 (40%), Positives = 93/175 (53%), Gaps = 24/175 (13%) Query: 144 ELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPH-NLIYY 202 E + P Y GQTALHIA+ + + V L+A+GA V A+A G F + Y+ Sbjct: 78 EFINSPFRDIYYRGQTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYF 137 Query: 203 GEHPLSFAACVGSEEIVRLLIEH---GADIRAQDSLGNTVLHILI-----LQPNKTFACQ 254 GE PLS AAC IV L E+ AD+R QDS GNTVLH L+ + N F + Sbjct: 138 GELPLSLAACTNQPHIVNYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTK 197 Query: 255 MYNLLLSYDGGDHLK--------SLELVPNNQGLTPFKLAGVEGNIVMFQHLMQK 301 MY+LLL LK +LE V NN GL+P +A G I +FQH++++ Sbjct: 198 MYDLLL-------LKCARLFPDSNLEAVLNNDGLSPLMMAAKTGKIGIFQHIIRR 245 >4N5Q-A nrPDB Length = 257 Score = 104 bits (260), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 61/158 (38%), Positives = 91/158 (57%), Gaps = 10/158 (6%) Query: 151 TSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYR-PHNLIYYGEHPLSF 209 T E YEGQTAL+IA+ + ++ L+A GA V+A A G F+ + H Y+GE PL+ Sbjct: 93 TEEAYEGQTALNIAIERRQGDITAVLIAAGADVNAHAKGVFFNPKYQHEGFYFGETPLAL 152 Query: 210 AACVGSEEIVRLLIEH-GADIRAQDSLGNTVLHILI-----LQPNKTFACQMYNLLLSYD 263 AAC EIV+LL+E+ DI +QDS GN +LH L+ + F +MY+++L Sbjct: 153 AACTNQPEIVQLLMENEQTDITSQDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILLRS 212 Query: 264 GGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQK 301 G LE + NN GLTP +LA G + ++++ + Sbjct: 213 GN---WELETMRNNDGLTPLQLAAKMGKAEILKYILSR 247 >2F37-A nrPDB Length = 251 Score = 104 bits (259), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 78/221 (35%), Positives = 113/221 (51%), Gaps = 22/221 (9%) Query: 101 LIKLLKFEGCEVHQKGAMGETALHIAAL--YDNLEAAMVLM------EAAPE-LVFEPMT 151 L K K+ + +G+ G+T L A L D + A ++ + P+ LV T Sbjct: 30 LSKTSKYLTDSEYTEGSTGKTCLMKAVLNLKDGVNACILPLLQIDRDSGNPQPLVNAQCT 89 Query: 152 SELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAA 211 + Y G +ALHIA+ +++ V+ L+ GA+V ARA G F Y+GE PLS AA Sbjct: 90 DDYYRGHSALHIAIEKRSLQCVKLLVENGANVHARACGRFFQKGQGTCFYFGELPLSLAA 149 Query: 212 CVGSEEIVRLLIEH---GADIRAQDSLGNTVLHILIL-----QPNKTFACQMYNLLLSYD 263 C ++V L+E+ A ++A DS GNTVLH L++ N MY+ LL Sbjct: 150 CTKQWDVVSYLLENPHQPASLQATDSQGNTVLHALVMISDNSAENIALVTSMYDGLLQ-- 207 Query: 264 GGDHL---KSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQK 301 G L LE + N Q LTP KLA EG I +F+H++Q+ Sbjct: 208 AGARLCPTVQLEDIRNLQDLTPLKLAAKEGKIEIFRHILQR 248 >5MIO-C nrPDB Length = 573 Score = 71.6 bits (174), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 49/150 (32%), Positives = 74/150 (49%), Gaps = 18/150 (12%) Query: 90 LLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEP 149 LL A +++L G +V+ A G T LH+AA Y +LE VL++ ++ Sbjct: 414 LLEAARAGQDDEVRVLMANGADVNATDASGLTPLHLAATYGHLEIVEVLLKHGADVSASD 473 Query: 150 MTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSF 209 + G T LH+A + ++ +V LL GA V+A T +G+ PL Sbjct: 474 LM-----GSTPLHLAALIGHLEIVEVLLKHGADVNAVDT-------------WGDTPLRL 515 Query: 210 AACVGSEEIVRLLIEHGADIRAQDSLGNTV 239 AA +G +IV L++HGAD+ AQD G T Sbjct: 516 AAVMGHLKIVEALLKHGADVNAQDKFGKTA 545 Score = 55.1 bits (131), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 53/174 (30%), Positives = 85/174 (48%), Gaps = 30/174 (17%) Query: 157 GQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSE 216 G+ L A Q+ + VR L+A GA V+A G PL AA G Sbjct: 411 GKKLLEAARAGQD-DEVRVLMANGADVNATDAS-------------GLTPLHLAATYGHL 456 Query: 217 EIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPN 276 EIV +L++HGAD+ A D +G+T LH+ L + ++ +LL + G + +++ Sbjct: 457 EIVEVLLKHGADVSASDLMGSTPLHLAALIGH----LEIVEVLLKH--GADVNAVD---- 506 Query: 277 NQGLTPFKLAGVEGNIVMFQHLMQKRKHI--QWTYGPLTSTLYDLTEIDSSGDD 328 G TP +LA V G++ + + L++ + Q +G T YD T ID+ +D Sbjct: 507 TWGDTPLRLAAVMGHLKIVEALLKHGADVNAQDKFG---KTAYD-TSIDNGSED 556 >6MWQ-A nrPDB Length = 493 Score = 70.1 bits (170), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 53/160 (33%), Positives = 79/160 (49%), Gaps = 18/160 (11%) Query: 102 IKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTAL 161 +++L G +V+ G T LH+AA +LE VL++ ++ ++L+ GQT L Sbjct: 21 VRILMANGADVNALDRFGLTPLHLAAQRGHLEIVEVLLKCGADV----NAADLW-GQTPL 75 Query: 162 HIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRL 221 H+A ++ +V LL GA V+A L G+ PL A G EIV + Sbjct: 76 HLAATAGHLEIVEVLLKYGADVNA-------------LDLIGKTPLHLTAIDGHLEIVEV 122 Query: 222 LIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLS 261 L++HGAD+ AQD G T I I N+ A + L LS Sbjct: 123 LLKHGADVNAQDKFGKTAFDISIDNGNEDLAEILQKLNLS 162 Score = 37.4 bits (85), Expect = 0.026, Method: Compositional matrix adjust. Identities = 28/94 (29%), Positives = 53/94 (56%), Gaps = 7/94 (7%) Query: 84 IW-ESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAA 142 +W ++PL LAA +++ + LLK+ G +V+ +G+T LH+ A+ +LE VL++ Sbjct: 69 LWGQTPLHLAATAGHLEIVEVLLKY-GADVNALDLIGKTPLHLTAIDGHLEIVEVLLKHG 127 Query: 143 PELVFEPMTSELYEGQTALHIAVINQNVNLVRAL 176 + + ++ G+TA I++ N N +L L Sbjct: 128 AD-----VNAQDKFGKTAFDISIDNGNEDLAEIL 156 >6FES-A nrPDB Length = 367 Score = 60.8 bits (146), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 44/137 (32%), Positives = 65/137 (47%), Gaps = 18/137 (13%) Query: 102 IKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTAL 161 +++L G +V+ G T LH+AA +L VL++ ++ + G T L Sbjct: 22 VRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADV-----NANDERGHTPL 76 Query: 162 HIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRL 221 H+A ++ +V LL GA V+A G PL AA G EEIV + Sbjct: 77 HLAAYTGHLEIVEVLLKNGAGVNATDV-------------IGTAPLHLAAMWGHEEIVEV 123 Query: 222 LIEHGADIRAQDSLGNT 238 L+++GAD RAQD G T Sbjct: 124 LLKNGADARAQDKFGKT 140 Score = 43.9 bits (102), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 29/86 (33%), Positives = 41/86 (47%), Gaps = 13/86 (15%) Query: 157 GQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSE 216 G T LH+A ++ +V LL GA V+A G PL AA G Sbjct: 39 GFTPLHLAAWEGHLGIVEVLLKNGADVNANDE-------------RGHTPLHLAAYTGHL 85 Query: 217 EIVRLLIEHGADIRAQDSLGNTVLHI 242 EIV +L+++GA + A D +G LH+ Sbjct: 86 EIVEVLLKNGAGVNATDVIGTAPLHL 111 Score = 39.3 bits (90), Expect = 0.007, Method: Compositional matrix adjust. Identities = 28/71 (39%), Positives = 36/71 (50%), Gaps = 15/71 (21%) Query: 173 VRALLARGASV-SARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRA 231 VR LLA GA V +A TG PL AA G IV +L+++GAD+ A Sbjct: 22 VRILLANGADVNTADETGFT--------------PLHLAAWEGHLGIVEVLLKNGADVNA 67 Query: 232 QDSLGNTVLHI 242 D G+T LH+ Sbjct: 68 NDERGHTPLHL 78 Score = 31.6 bits (70), Expect = 1.5, Method: Compositional matrix adjust. Identities = 28/108 (25%), Positives = 48/108 (44%), Gaps = 28/108 (25%) Query: 210 AACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLK 269 AA G ++ VR+L+ +GAD+ D G T LH L +++G HL Sbjct: 13 AARAGQDDEVRILLANGADVNTADETGFTPLH-----------------LAAWEG--HLG 53 Query: 270 SLELVPNN---------QGLTPFKLAGVEGNIVMFQHLMQKRKHIQWT 308 +E++ N +G TP LA G++ + + L++ + T Sbjct: 54 IVEVLLKNGADVNANDERGHTPLHLAAYTGHLEIVEVLLKNGAGVNAT 101 >6AUN-A nrPDB Length = 752 Score = 60.5 bits (145), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 57/234 (24%), Positives = 98/234 (41%), Gaps = 38/234 (16%) Query: 87 SPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 +PL LA ++ + + L++L+++ ++ GETA H A DN + +L + A Sbjct: 154 TPLHLACRKGDSEILVELVQYCHAQMDVTDNKGETAFHYAVQGDNSQVLQLLGKNASA-- 211 Query: 147 FEPMTSELYEGQTALHIAVINQNVNLVRALLARGA----------------SVSARATGS 190 + +G T LH+A +VR LL A S + Sbjct: 212 --GLNQVNKQGLTPLHLACQMGKQEMVRVLLLCNARCNVMGPSGFPIHTAMKFSQKGCAE 269 Query: 191 VFHYRPHNLIY-----YGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILIL 245 + + I+ YG PL +A + E+ R+L++ G D+ + + GNT LH+ ++ Sbjct: 270 MIISMDSSQIHSKDPRYGASPLHWAK---NAEMARMLLKRGCDVDSTSAAGNTALHVAVM 326 Query: 246 QPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLM 299 + F C M L + G P G TP LA + N+ M + L+ Sbjct: 327 R--NRFDCVMVLLTYGANAG--------TPGEHGNTPLHLAISKDNMEMIKALI 370 Score = 48.9 bits (115), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 31/101 (30%), Positives = 47/101 (46%), Gaps = 9/101 (8%) Query: 83 RIWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAA 142 R SPL A + L+K GC+V A G TALH+A + + + MVL+ Sbjct: 285 RYGASPLHWAKNAEMARMLLK----RGCDVDSTSAAGNTALHVAVMRNRFDCVMVLLTYG 340 Query: 143 PELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASV 183 + G T LH+A+ N+ +++AL+ GA V Sbjct: 341 AN-----AGTPGEHGNTPLHLAISKDNMEMIKALIVFGAEV 376 Score = 39.7 bits (91), Expect = 0.005, Method: Compositional matrix adjust. Identities = 37/152 (24%), Positives = 62/152 (40%), Gaps = 22/152 (14%) Query: 88 PLLLAAKENNVQALIKLLKFEGCEVHQKGA-MGETALHIAALYDNLEAAMVLMEAAPELV 146 P+ A K + ++ + ++H K G + LH A N E A +L++ ++ Sbjct: 255 PIHTAMKFSQKGCAEMIISMDSSQIHSKDPRYGASPLHWAK---NAEMARMLLKRGCDV- 310 Query: 147 FEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHP 206 S G TALH+AV+ + V LL GA+ +G P Sbjct: 311 ----DSTSAAGNTALHVAVMRNRFDCVMVLLTYGANAGTPGE-------------HGNTP 353 Query: 207 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNT 238 L A + E+++ LI GA++ + G T Sbjct: 354 LHLAISKDNMEMIKALIVFGAEVDTPNDFGET 385 >5AQA-A nrPDB Length = 418 Score = 58.5 bits (140), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 49/166 (29%), Positives = 78/166 (46%), Gaps = 18/166 (10%) Query: 90 LLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEP 149 LL A +++L G +V+ G T LH+AA +LE VL++ ++ Sbjct: 18 LLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVD--- 74 Query: 150 MTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSF 209 S+++ G T LH+A ++ +V LL GA V+A + G PL Sbjct: 75 -ASDVF-GYTPLHLAAYWGHLEIVEVLLKNGADVNA-------------MDSDGMTPLHL 119 Query: 210 AACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQM 255 AA G +EIV +L++ GAD+ AQD G L + Q + A ++ Sbjct: 120 AAKWGYKEIVEVLLKAGADVDAQDKFGKRPLWLAADQGHAEIAAKL 165 >5AQ7-A nrPDB Length = 418 Score = 57.0 bits (136), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 47/166 (28%), Positives = 73/166 (43%), Gaps = 18/166 (10%) Query: 90 LLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEP 149 LL A +++L G +V+ G T LH+AA +L VL++ ++ Sbjct: 18 LLEAARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADV---- 73 Query: 150 MTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSF 209 + G T LH+A ++ +V LL GA V+A G PL Sbjct: 74 -NANDERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATDV-------------IGTAPLHL 119 Query: 210 AACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQM 255 AA G +EIV +L++ GAD+ AQD G L + Q + A ++ Sbjct: 120 AAMWGYKEIVEVLLKAGADVDAQDKFGKRPLWLAADQGHAEIAAKL 165 >5AQB-A nrPDB Length = 428 Score = 56.6 bits (135), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 49/171 (28%), Positives = 79/171 (46%), Gaps = 22/171 (12%) Query: 103 KLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALH 162 ++L G +V+ +G T LH+AA + +LE L++ ++ + +G T LH Sbjct: 31 RILMANGADVNALDEVGWTPLHLAA-WGHLEIVECLLKNGADV-----NAADIDGYTPLH 84 Query: 163 IAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLL 222 +A + ++ +V LL GA V+A G PL AA G EIV +L Sbjct: 85 LAAFSGHLEIVEVLLKYGADVNADDQA-------------GFTPLHLAAIFGHLEIVEVL 131 Query: 223 IEHGADIRAQDSLGNTVLHILILQPNKTFA---CQMYNLLLSYDGGDHLKS 270 +++GAD+ AQD G T + I N+ A + L+ D D L + Sbjct: 132 LKNGADVNAQDKFGKTPRDLAIDNGNEDIAEVLGKAATLVKVKDAADQLGA 182 Score = 34.3 bits (77), Expect = 0.21, Method: Compositional matrix adjust. Identities = 24/91 (26%), Positives = 44/91 (48%), Gaps = 11/91 (12%) Query: 210 AACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLK 269 AA G ++ R+L+ +GAD+ A D +G T LH+ + C + N G + Sbjct: 21 AARAGQDDECRILMANGADVNALDEVGWTPLHLAAWGHLEIVECLLKN-------GADVN 73 Query: 270 SLELVPNNQGLTPFKLAGVEGNIVMFQHLMQ 300 + ++ G TP LA G++ + + L++ Sbjct: 74 AADI----DGYTPLHLAAFSGHLEIVEVLLK 100 >3B7B-A nrPDB Length = 237 Score = 52.0 bits (123), Expect = 1e-06, Method: Composition-based stats. Identities = 56/206 (27%), Positives = 95/206 (46%), Gaps = 28/206 (13%) Query: 87 SPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 +PL+ AA+ N+++A+ L+K G V K A G T LH+AA + E L+ V Sbjct: 46 TPLMEAAENNHLEAVKYLIK-AGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDV 104 Query: 147 FEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHP 206 + G T + A ++V+LV+ LL++G+ ++ R N+ H Sbjct: 105 ----NCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDN-------EENICL---HW 150 Query: 207 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGD 266 +F+ CV +I +L+ D+ A + G++ LHI + + C + L LS D Sbjct: 151 AAFSGCV---DIAEILLAAKCDLHAVNIHGDSPLHIAARE--NRYDCVV--LFLSRDSDV 203 Query: 267 HLKSLELVPNNQGLTPFKLAGVEGNI 292 LK N +G TP + A + + Sbjct: 204 TLK------NKEGETPLQCASLNSQV 223 Score = 30.0 bits (66), Expect = 3.9, Method: Composition-based stats. Identities = 18/56 (32%), Positives = 31/56 (55%), Gaps = 1/56 (1%) Query: 86 ESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEA 141 +SPL +AA+EN ++ L + +V K GET L A+L + +A+ + +A Sbjct: 178 DSPLHIAARENRYDCVVLFLSRDS-DVTLKNKEGETPLQCASLNSQVWSALQMSKA 232 >5AQ9-A nrPDB Length = 422 Score = 49.3 bits (116), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 56/199 (28%), Positives = 86/199 (43%), Gaps = 47/199 (23%) Query: 157 GQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSE 216 G+ L A Q+ + VR L+A GA V+A G PL AA G Sbjct: 15 GRKLLEAARAGQD-DEVRILMANGADVNAADN-------------TGTTPLHLAAYSGHL 60 Query: 217 EIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPN 276 EIV +L++HGAD+ A D G T LH L +Y G HL+ +E++ Sbjct: 61 EIVEVLLKHGADVDASDVFGYTPLH-----------------LAAYWG--HLEIVEVLLK 101 Query: 277 N---------QGLTPFKLAGVEGNIVMFQHLMQKRKHI--QWTYGPLTSTLYDLTEIDSS 325 N G+TP LA G + + + L++ + Q +G T +DL + + + Sbjct: 102 NGADVNAMDSDGMTPLHLAAKWGYLEIVEVLLKHGADVNAQDKFG---KTPFDLADDNGN 158 Query: 326 GDDQSLLELIVTTKKREAR 344 D +LL++ + AR Sbjct: 159 DDVGTLLQVAAAADQLGAR 177 Score = 43.9 bits (102), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 40/136 (29%), Positives = 65/136 (47%), Gaps = 19/136 (13%) Query: 87 SPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 +PL LAA +++ + LLK G +V G T LH+AA + +LE VL++ ++ Sbjct: 49 TPLHLAAYSGHLEIVEVLLKH-GADVDASDVFGYTPLHLAAYWGHLEIVEVLLKNGADV- 106 Query: 147 FEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHP 206 M S+ G T LH+A + +V LL GA V+A+ +G+ P Sbjct: 107 -NAMDSD---GMTPLHLAAKWGYLEIVEVLLKHGADVNAQDK-------------FGKTP 149 Query: 207 LSFAACVGSEEIVRLL 222 A G++++ LL Sbjct: 150 FDLADDNGNDDVGTLL 165 >6BY9-A nrPDB Length = 328 Score = 49.3 bits (116), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 56/206 (27%), Positives = 95/206 (46%), Gaps = 28/206 (13%) Query: 87 SPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 +PL+ AA+ N+++A+ L+K G V K A G T LH+AA + E L+ V Sbjct: 137 TPLMEAAENNHLEAVKYLIKA-GALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDV 195 Query: 147 FEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHP 206 + G T + A ++V+LV+ LL++G+ ++ R N+ H Sbjct: 196 ----NCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDN-------EENICL---HW 241 Query: 207 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGD 266 +F+ CV +I +L+ D+ A + G++ LHI + + C + L LS D Sbjct: 242 AAFSGCV---DIAEILLAAKCDLHAVNIHGDSPLHIAARE--NRYDCVV--LFLSRDSDV 294 Query: 267 HLKSLELVPNNQGLTPFKLAGVEGNI 292 LK N +G TP + A + + Sbjct: 295 TLK------NKEGETPLQCASLNSQV 314 >5H76-A nrPDB Length = 201 Score = 48.1 bits (113), Expect = 2e-05, Method: Composition-based stats. Identities = 53/182 (29%), Positives = 80/182 (43%), Gaps = 47/182 (25%) Query: 157 GQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSE 216 G+ L A Q+ + VR L+A GA V+A G PL AA G Sbjct: 7 GRKLLEAARAGQD-DEVRILMANGADVNAADNT-------------GTTPLHLAAYSGHL 52 Query: 217 EIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPN 276 EIV +L++HGAD+ A D G T LH L +Y G HL+ +E++ Sbjct: 53 EIVEVLLKHGADVDASDVFGYTPLH-----------------LAAYWG--HLEIVEVLLK 93 Query: 277 N---------QGLTPFKLAGVEGNIVMFQHLMQKRK-HIQWTYGPLTSTLYDLTEIDSSG 326 N G+TP LA G + + + L++ + Q +G T +D++ ID+ Sbjct: 94 NGADVNAMDSDGMTPLHLAAKWGYLEIVEVLLKHGAVNAQDKFG---KTAFDIS-IDNGN 149 Query: 327 DD 328 +D Sbjct: 150 ED 151 Score = 42.0 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 32/95 (33%), Positives = 49/95 (51%), Gaps = 6/95 (6%) Query: 87 SPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 +PL LAA +++ + LLK G +V G T LH+AA + +LE VL++ ++ Sbjct: 41 TPLHLAAYSGHLEIVEVLLK-HGADVDASDVFGYTPLHLAAYWGHLEIVEVLLKNGADV- 98 Query: 147 FEPMTSELYEGQTALHIAVINQNVNLVRALLARGA 181 M S+ G T LH+A + +V LL GA Sbjct: 99 -NAMDSD---GMTPLHLAAKWGYLEIVEVLLKHGA 129 >5CBO-A nrPDB Length = 176 Score = 47.8 bits (112), Expect = 2e-05, Method: Composition-based stats. Identities = 33/96 (34%), Positives = 44/96 (45%), Gaps = 13/96 (13%) Query: 157 GQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSE 216 G T LH+A + +V LL GA V+A G+ PL AA G Sbjct: 36 GVTPLHLAAYWGHFEIVEVLLKYGADVNASDAT-------------GDTPLHLAAKWGYL 82 Query: 217 EIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFA 252 IV +L+++GAD+ AQD G T I I N+ A Sbjct: 83 GIVEVLLKYGADVNAQDKFGKTAFDISIDNGNEDLA 118 Score = 46.2 bits (108), Expect = 5e-05, Method: Composition-based stats. Identities = 31/86 (36%), Positives = 45/86 (52%), Gaps = 14/86 (16%) Query: 157 GQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSE 216 G+ L A Q+ + VR L+A GA V+A +G PL AA G Sbjct: 4 GKKLLEAAHAGQD-DEVRILMANGADVNAMDN-------------FGVTPLHLAAYWGHF 49 Query: 217 EIVRLLIEHGADIRAQDSLGNTVLHI 242 EIV +L+++GAD+ A D+ G+T LH+ Sbjct: 50 EIVEVLLKYGADVNASDATGDTPLHL 75 Score = 38.5 bits (88), Expect = 0.012, Method: Composition-based stats. Identities = 30/99 (30%), Positives = 51/99 (51%), Gaps = 6/99 (6%) Query: 87 SPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 +PL LAA + + + LLK+ G +V+ A G+T LH+AA + L VL++ ++ Sbjct: 38 TPLHLAAYWGHFEIVEVLLKY-GADVNASDATGDTPLHLAAKWGYLGIVEVLLKYGADV- 95 Query: 147 FEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSA 185 ++ G+TA I++ N N +L L A +A Sbjct: 96 ----NAQDKFGKTAFDISIDNGNEDLAEILCKNKAQQAA 130 Score = 37.4 bits (85), Expect = 0.022, Method: Composition-based stats. Identities = 39/136 (28%), Positives = 68/136 (50%), Gaps = 18/136 (13%) Query: 210 AACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLK 269 AA G ++ VR+L+ +GAD+ A D+ G T LH+ + ++ +LL Y G D Sbjct: 10 AAHAGQDDEVRILMANGADVNAMDNFGVTPLHLAAYWGH----FEIVEVLLKY-GADVNA 64 Query: 270 SLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKRKHI--QWTYGPLTSTLYDLTEIDSSGD 327 S + G TP LA G + + + L++ + Q +G T +D++ ID+ + Sbjct: 65 S-----DATGDTPLHLAAKWGYLGIVEVLLKYGADVNAQDKFG---KTAFDIS-IDNGNE 115 Query: 328 DQSLLELIVTTKKREA 343 D L E++ K ++A Sbjct: 116 D--LAEILCKNKAQQA 129 >4NIK-A nrPDB Length = 230 Score = 45.1 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 44/156 (28%), Positives = 66/156 (42%), Gaps = 19/156 (12%) Query: 87 SPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 SPL +AA ++K L +G +V+ G T LH AA + E A++L+E Sbjct: 79 SPLHIAASAGR-DEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGA--- 134 Query: 147 FEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHP 206 P + YE TA+H A N+ ++ LL AS + + T G P Sbjct: 135 -NPDAKDHYEA-TAMHRAAAKGNLKMIHILLYYKASTNIQDT-------------EGNTP 179 Query: 207 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHI 242 L A E +LL+ GA I ++ T L + Sbjct: 180 LHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQV 215 Score = 40.4 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 41/157 (26%), Positives = 62/157 (39%), Gaps = 25/157 (15%) Query: 156 EGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGS 215 + +TALH A + +V LL G V+ + G PL AA G Sbjct: 43 DSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDA-------------GWSPLHIAASAGR 89 Query: 216 EEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVP 275 +EIV+ L+ GA + A + G T LH + A + + D DH ++ Sbjct: 90 DEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEA----- 144 Query: 276 NNQGLTPFKLAGVEGNIVMFQHLM--QKRKHIQWTYG 310 T A +GN+ M L+ + +IQ T G Sbjct: 145 -----TAMHRAAAKGNLKMIHILLYYKASTNIQDTEG 176 Score = 39.7 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 37/142 (26%), Positives = 60/142 (42%), Gaps = 25/142 (17%) Query: 121 TALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARG 180 TALH A + E L++ P+ + G + LHIA +V+ALL +G Sbjct: 46 TALHWACSAGHTEIVEFLLQLGV-----PVNDKDDAGWSPLHIAASAGRDEIVKALLGKG 100 Query: 181 ASVSA--RATGSVFHY------------------RPHNLIYYGEHPLSFAACVGSEEIVR 220 A V+A + + HY P +Y + AA G+ +++ Sbjct: 101 AQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIH 160 Query: 221 LLIEHGADIRAQDSLGNTVLHI 242 +L+ + A QD+ GNT LH+ Sbjct: 161 ILLYYKASTNIQDTEGNTPLHL 182 >4Z68-A nrPDB Length = 155 Score = 45.1 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 34/107 (31%), Positives = 46/107 (42%), Gaps = 24/107 (22%) Query: 159 TALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEH------------- 205 T LH A V++V LL GA V A+ G + HN YG + Sbjct: 39 TPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPL--HNACSYGHYEVAELLVKHGAVV 96 Query: 206 ---------PLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHIL 243 PL AA G EI +LL++HGAD ++ GNT L ++ Sbjct: 97 NVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLV 143 >5GP7-A nrPDB Length = 169 Score = 44.3 bits (103), Expect = 2e-04, Method: Composition-based stats. Identities = 42/157 (26%), Positives = 66/157 (42%), Gaps = 18/157 (11%) Query: 86 ESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPEL 145 ++ LL AAK+ + + KL E T LH+AA Y+NLE A L+E ++ Sbjct: 10 DAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADV 69 Query: 146 VFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEH 205 ++ G LH A +V++ L+ V+A + Sbjct: 70 -----NAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDK-------------WAFT 111 Query: 206 PLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHI 242 PL AA G ++ LL+ HGAD ++ G T L + Sbjct: 112 PLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDL 148 >4OAU-C nrPDB Length = 699 Score = 43.5 bits (101), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 49/166 (29%), Positives = 77/166 (46%), Gaps = 16/166 (9%) Query: 81 QKRIWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLME 140 +K+ +P +LAA +V+ L+KL +G +V++ G TA AA+Y ++A L + Sbjct: 68 RKKNGATPFILAAIAGSVK-LLKLFLSKGADVNECDFYGFTAFMEAAVYGKVKALKFLYK 126 Query: 141 AAPELVFEPMTSELYE-----GQTALHIAVINQNVNLVRALLAR-GASVSARATGSVFHY 194 + T E E G TAL A +V +++ LL GA V+A + Sbjct: 127 RGANVNLRRKTKEDQERLRKGGATALMDAAEKGHVEVLKILLDEMGADVNA-----CDNM 181 Query: 195 RPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVL 240 + LI H L + E I LL++HGAD+ + G T L Sbjct: 182 GRNALI----HALLSSDDSDVEAITHLLLDHGADVNVRGERGKTPL 223 Score = 42.0 bits (97), Expect = 0.001, Method: Compositional matrix adjust. Identities = 51/185 (27%), Positives = 84/185 (45%), Gaps = 23/185 (12%) Query: 157 GQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSE 216 G TA A + V ++ L RGA+V+ R R L G L AA G Sbjct: 105 GFTAFMEAAVYGKVKALKFLYKRGANVNLRRKTKEDQER---LRKGGATALMDAAEKGHV 161 Query: 217 EIVRLLI-EHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVP 275 E++++L+ E GAD+ A D++G L +L + + + +LLL DH + V Sbjct: 162 EVLKILLDEMGADVNACDNMGRNALIHALLSSDDSDVEAITHLLL-----DHGADVN-VR 215 Query: 276 NNQGLTPFKLAGVEGNIVMFQHLMQKRKHIQWTYGPLTSTLYDLTEIDSSGDDQSLLELI 335 +G TP LA + ++ + Q L++ ++HI+ + + DS G LL + Sbjct: 216 GERGKTPLILAVEKKHLGLVQRLLE-QEHIE------------INDTDSDGKTALLLAVE 262 Query: 336 VTTKK 340 + KK Sbjct: 263 LKLKK 267 Score = 35.0 bits (79), Expect = 0.12, Method: Compositional matrix adjust. Identities = 24/65 (36%), Positives = 34/65 (52%), Gaps = 12/65 (18%) Query: 164 AVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLI 223 AV N++V+LV+ LL GA+V+ + G PL A + E+IV LL+ Sbjct: 12 AVQNEDVDLVQQLLEGGANVNFQEEEG------------GWTPLHNAVQMSREDIVELLL 59 Query: 224 EHGAD 228 HGAD Sbjct: 60 RHGAD 64 Score = 33.5 bits (75), Expect = 0.34, Method: Compositional matrix adjust. Identities = 27/95 (28%), Positives = 49/95 (51%), Gaps = 4/95 (4%) Query: 90 LLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEP 149 LL++ +++V+A+ LL G +V+ +G G+T L +A +L L+E + + Sbjct: 190 LLSSDDSDVEAITHLLLDHGADVNVRGERGKTPLILAVEKKHLGLVQRLLEQEHIEINDT 249 Query: 150 MTSELYEGQTALHIAVINQNVNLVRALLARGASVS 184 + +G+TAL +AV + + L RGAS Sbjct: 250 DS----DGKTALLLAVELKLKKIAELLCKRGASTD 280 >6G1K-A nrPDB Length = 921 Score = 42.7 bits (99), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 31/137 (22%), Positives = 68/137 (49%), Gaps = 19/137 (13%) Query: 514 LGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAF---YIIFQTED------------PDE 558 LGP I + +M+ D+++F ++ +V+L FA+ Y ++ + + Sbjct: 502 LGPLQISLGRMLL-DILKFLFIYCLVLLAFANGLNQLYFYYENSEGMTCKGIRCERQNNA 560 Query: 559 LGHFYDYPMALF-STFELF-LTIIDGPANYDVDLPFMYSITYAAFAIIATLLMLNLLIAM 616 ++ +LF S F L L + + A++ F+ + + + +I+ +++LN+LIAM Sbjct: 561 FSTLFETLQSLFWSIFGLISLYVTNVKADHKFT-EFVGATMFGTYNVISLVVLLNMLIAM 619 Query: 617 MGDTHWRVAHERDELWR 633 M +++ +A D W+ Sbjct: 620 MNNSYQHIADHADIEWK 636 >4O1O-A nrPDB Length = 717 Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust. Identities = 51/174 (29%), Positives = 80/174 (45%), Gaps = 16/174 (9%) Query: 81 QKRIWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLME 140 +KR +P ++A NV+ L++LL +V++ G TA AA+Y +EA L E Sbjct: 71 RKRNGATPFIIAGITGNVR-LLQLLLPNVEDVNECDVNGFTAFMEAAVYGRVEALRFLYE 129 Query: 141 AAPELVFEPMTSELYE-----GQTALHIAVINQNVNLVRALL-ARGASVSARATGSVFHY 194 ++ T + E G TAL A +V +V LL A A V AR + Sbjct: 130 NGADVNMHRKTKQDQERIRKGGATALMDAAEKGHVGVVTILLHAMKAEVDARD-----NM 184 Query: 195 RPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPN 248 + L+Y +P A + I RLL++HGAD+ + T L + + + N Sbjct: 185 GRNALVYALLNPDDGKA----KAITRLLLDHGADVNVRGEGSKTPLILAVERKN 234 Score = 33.1 bits (74), Expect = 0.48, Method: Compositional matrix adjust. Identities = 28/95 (29%), Positives = 47/95 (49%), Gaps = 4/95 (4%) Query: 90 LLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEP 149 LL + +A+ +LL G +V+ +G +T L +A NL+ +L+E V + Sbjct: 193 LLNPDDGKAKAITRLLLDHGADVNVRGEGSKTPLILAVERKNLDLVQMLLEQEQIEVNDT 252 Query: 150 MTSELYEGQTALHIAVINQNVNLVRALLARGASVS 184 EG+TAL +AV + + + L RGAS + Sbjct: 253 DR----EGKTALLLAVELRLEEIAKLLCHRGASTN 283 Score = 32.7 bits (73), Expect = 0.56, Method: Compositional matrix adjust. Identities = 22/65 (33%), Positives = 32/65 (49%), Gaps = 12/65 (18%) Query: 164 AVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLI 223 AV ++ VR LL RGA + + +G PL A + SE++V LL+ Sbjct: 15 AVQEADIEQVRQLLERGADANFQEE------------EWGWSPLHSAVQMDSEDLVALLL 62 Query: 224 EHGAD 228 +HGAD Sbjct: 63 KHGAD 67 Score = 32.7 bits (73), Expect = 0.60, Method: Compositional matrix adjust. Identities = 55/224 (24%), Positives = 91/224 (40%), Gaps = 15/224 (6%) Query: 81 QKRIWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLME 140 Q+ W L +A + + + L+ LL G + + G T IA + N+ +L+ Sbjct: 37 QEEEWGWSPLHSAVQMDSEDLVALLLKHGADPCLRKRNGATPFIIAGITGNVRLLQLLL- 95 Query: 141 AAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLI 200 P + E + G TA A + V +R L GA V+ R + Sbjct: 96 --PNV--EDVNECDVNGFTAFMEAAVYGRVEALRFLYENGADVNMHRKTKQDQER---IR 148 Query: 201 YYGEHPLSFAACVGSEEIVRLLIEH-GADIRAQDSLGNTVLHILILQPNKTFACQMYNLL 259 G L AA G +V +L+ A++ A+D++G L +L P+ A + LL Sbjct: 149 KGGATALMDAAEKGHVGVVTILLHAMKAEVDARDNMGRNALVYALLNPDDGKAKAITRLL 208 Query: 260 LSYDGGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKRK 303 L DH + V TP LA N+ + Q L+++ + Sbjct: 209 L-----DHGADVN-VRGEGSKTPLILAVERKNLDLVQMLLEQEQ 246 >6BWF-A nrPDB Length = 954 Score = 40.8 bits (94), Expect = 0.003, Method: Compositional matrix adjust. Identities = 57/232 (24%), Positives = 102/232 (43%), Gaps = 30/232 (12%) Query: 497 LVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFY-IIFQTED 555 ++ + ++ F Q GP+ +MI KM+ ++ +MA+V+L F I++ E+ Sbjct: 623 IIFWYVRLLDFLAVNQQAGPYVMMIGKMV-ANMFYIVVIMALVLLSFGVPRKAILYPHEE 681 Query: 556 PD-ELGH---FYDYPMALFSTFELFLTIIDGPANYDVDLP-------FMYSITYAAFAII 604 P L F+ Y M +F E++ ID AN D LP ++ A + + Sbjct: 682 PSWSLAKDIVFHPYWM-IFG--EVYAYEIDVCAN-DSTLPTICGPGTWLTPFLQAVYLFV 737 Query: 605 ATLLMLNLLIAMMGDTHWRVAHERDELWRAQVVATTVMLERK--LPRCLWPRSGI----- 657 ++M+NLLIA + + +V + +W+ Q + K LP L S I Sbjct: 738 QYIIMVNLLIAFFNNVYLQVKAISNIVWKYQRYHFIMAYHEKPVLPPPLIILSHIVSLFC 797 Query: 658 --CGR----EYGLGDRWFLRVEDRQDLNRQRIRRYAQAFQQQDDLYSEDLEK 703 C R + G + FL ED++ L+ + F ++DD ++ E+ Sbjct: 798 CVCKRRKKDKTSDGPKLFLTEEDQKKLHDFEEQCVEMYFDEKDDKFNSGSEE 849 >5Z96-A nrPDB Length = 755 Score = 40.4 bits (93), Expect = 0.003, Method: Compositional matrix adjust. Identities = 31/137 (22%), Positives = 68/137 (49%), Gaps = 19/137 (13%) Query: 514 LGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAF---YIIFQT------------EDPDE 558 LGP I + +M+ D+++F ++ +V+L FA+ Y ++ + + Sbjct: 502 LGPLQISLGRMLL-DILKFLFIYCLVLLAFANGLNQLYFYYEETKGLSCKGIRCEKQNNA 560 Query: 559 LGHFYDYPMALF-STFELF-LTIIDGPANYDVDLPFMYSITYAAFAIIATLLMLNLLIAM 616 ++ +LF S F L L + + A ++ F+ + + + +I+ +++LN+LIAM Sbjct: 561 FSTLFETLQSLFWSIFGLINLYVTNVKAQHEFT-EFVGATMFGTYNVISLVVLLNMLIAM 619 Query: 617 MGDTHWRVAHERDELWR 633 M +++ +A D W+ Sbjct: 620 MNNSYQLIADHADIEWK 636 >5DND-A nrPDB Length = 588 Score = 40.4 bits (93), Expect = 0.003, Method: Compositional matrix adjust. Identities = 43/138 (31%), Positives = 56/138 (40%), Gaps = 22/138 (15%) Query: 99 QALIKLLKFEGCEVH---QKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELY 155 Q + +L GC+ Q M AL +A LEA LME +L + Sbjct: 400 QGVARLFSLFGCQEEDSVQDAVMPSLALALAH-AGELEALQALMELGSDLRLKD-----S 453 Query: 156 EGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGS 215 GQT LH+A N +V LL RG V+AR + P L G H Sbjct: 454 NGQTLLHVAARNGRDGVVTMLLHRGMDVNARDRDGL---SPLLLAVQGRH---------- 500 Query: 216 EEIVRLLIEHGADIRAQD 233 E +RLL + GA + QD Sbjct: 501 RECIRLLRKAGACLSPQD 518 Score = 30.8 bits (68), Expect = 2.1, Method: Compositional matrix adjust. Identities = 14/32 (43%), Positives = 22/32 (68%) Query: 211 ACVGSEEIVRLLIEHGADIRAQDSLGNTVLHI 242 A G E ++ L+E G+D+R +DS G T+LH+ Sbjct: 430 AHAGELEALQALMELGSDLRLKDSNGQTLLHV 461 >4OT9-A nrPDB Length = 359 Score = 40.0 bits (92), Expect = 0.004, Method: Compositional matrix adjust. Identities = 28/83 (33%), Positives = 44/83 (53%), Gaps = 14/83 (16%) Query: 152 SELYEGQTALHIAVINQNVNLVRALLAR-GASVSARATGSVFHYRPHNLIYYGEHPLSFA 210 +E G+TALH+A + + LV L+ + A+V+AR + G PL A Sbjct: 223 TERQGGRTALHLATEMEELGLVTHLVTKLRANVNAR-------------TFAGNTPLHLA 269 Query: 211 ACVGSEEIVRLLIEHGADIRAQD 233 A +G + RLL++ GADI A++ Sbjct: 270 AGLGYPTLTRLLLKAGADIHAEN 292 Score = 33.1 bits (74), Expect = 0.42, Method: Compositional matrix adjust. Identities = 32/141 (22%), Positives = 60/141 (42%), Gaps = 18/141 (12%) Query: 150 MTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEH---- 205 +T++ G T LH+A+I+ +++ ++ + H + ++ H Sbjct: 75 LTAQDENGDTPLHLAIIHGQTSVIEQIVY-----------VIHHAQDLGVVNLTNHLHQT 123 Query: 206 PLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGG 265 PL A G +V L+ GAD D G++ +H+ + A ++ LL G Sbjct: 124 PLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRA--GAGAPELLRALLQ-SGA 180 Query: 266 DHLKSLELVPNNQGLTPFKLA 286 + L +P+ +GL P LA Sbjct: 181 PAVPQLLHMPDFEGLYPVHLA 201 Score = 32.7 bits (73), Expect = 0.66, Method: Compositional matrix adjust. Identities = 41/155 (26%), Positives = 67/155 (43%), Gaps = 33/155 (21%) Query: 119 GETALHIAALYDN---LEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRA 175 G+T LH+A ++ +E + ++ A +L +T+ L+ QT LH+AVI ++V Sbjct: 82 GDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLH--QTPLHLAVITGQTSVVSF 139 Query: 176 LLARGASVS--ARATGSVFHYR----------------------P---HNLIYYGEHPLS 208 LL GA + R S H P H + G +P+ Sbjct: 140 LLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEGLYPVH 199 Query: 209 FAACVGSEEIVRLLIEHGADIRAQDSLGN-TVLHI 242 A S E + LL++ GA++ A + G T LH+ Sbjct: 200 LAVRARSPECLDLLVDSGAEVEATERQGGRTALHL 234 >3EU9-A nrPDB Length = 240 Score = 39.7 bits (91), Expect = 0.005, Method: Compositional matrix adjust. Identities = 47/185 (25%), Positives = 77/185 (41%), Gaps = 32/185 (17%) Query: 89 LLLAAKENNVQALIKLLKFEGCEVHQKGA-MGETALHIAALYDNLEAAMVLME--AAPEL 145 LL A NN L+K +G V Q G + T LH A +L + LM+ A P L Sbjct: 45 LLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSL 104 Query: 146 VFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVF-----HYRPHNL- 199 + EG + +H+A + ++V L+A+G V + YR H++ Sbjct: 105 IDG-------EGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVD 157 Query: 200 ----------------IYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHIL 243 Y+ L +A G+ ++ LL+E GA++ AQ+ G + L + Sbjct: 158 PTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGANVDAQNIKGESALDLA 217 Query: 244 ILQPN 248 + N Sbjct: 218 KQRKN 222 Score = 32.7 bits (73), Expect = 0.64, Method: Compositional matrix adjust. Identities = 46/197 (23%), Positives = 70/197 (35%), Gaps = 52/197 (26%) Query: 156 EGQTALHIAVINQNVNLVRALLARGASVS---ARATGSVFHYRPH--------NLIYYGE 204 E T LH A IN ++LV+ +++GA V + H+ L+ YG Sbjct: 41 ENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGA 100 Query: 205 HP----------LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQ 254 P + AA G IV LI G D+ D G T L+ +T + Sbjct: 101 DPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTP---LMWAAYRTHSVD 157 Query: 255 MYNLLLSYD-----GGDHLKSLEL-----------------------VPNNQGLTPFKLA 286 LLL+++ G + K+ L N +G + LA Sbjct: 158 PTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGANVDAQNIKGESALDLA 217 Query: 287 GVEGNIVMFQHLMQKRK 303 N+ M HL + R+ Sbjct: 218 KQRKNVWMINHLQEARQ 234 >5HKP-A nrPDB Length = 351 Score = 38.9 bits (89), Expect = 0.009, Method: Compositional matrix adjust. Identities = 36/112 (32%), Positives = 52/112 (46%), Gaps = 21/112 (18%) Query: 158 QTALHIAVIN---QNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVG 214 +TALH AV + + + LL +GA+V+ + + PL AA Sbjct: 212 ETALHCAVASLHPKRKQVAELLLRKGANVNEKNKDFMT-------------PLHVAAERA 258 Query: 215 SEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGD 266 +++ +L +HGA + A DSLG T LH L + Q LLLSY G D Sbjct: 259 HNDVMEVLHKHGAKMNALDSLGQTALHRAALAGH----LQTCRLLLSY-GSD 305 Score = 34.3 bits (77), Expect = 0.21, Method: Compositional matrix adjust. Identities = 17/36 (47%), Positives = 22/36 (61%) Query: 206 PLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLH 241 PL AA IV+LL++HGAD+ A+D G LH Sbjct: 61 PLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLH 96 Score = 30.0 bits (66), Expect = 4.2, Method: Compositional matrix adjust. Identities = 31/95 (32%), Positives = 46/95 (48%), Gaps = 6/95 (6%) Query: 87 SPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 +PL LAA N V+ +++LL G +VH K G LH A Y + E +L++ Sbjct: 60 TPLHLAAGYNRVR-IVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGA--C 116 Query: 147 FEPMTSELYEGQTALHIAVINQNVNLVRALLARGA 181 M +L++ T LH A V + LL+ GA Sbjct: 117 VNAM--DLWQF-TPLHEAASKNRVEVCSLLLSHGA 148 >1BLX-B nrPDB Length = 166 Score = 38.1 bits (87), Expect = 0.014, Method: Compositional matrix adjust. Identities = 25/84 (29%), Positives = 43/84 (51%), Gaps = 11/84 (13%) Query: 203 GEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSY 262 G P+ AA G + +++L+EHGAD+ A DS G+ +H+ I + + + L+ Sbjct: 74 GTSPVHDAARTGFLDTLKVLVEHGADVNALDSTGSLPIHLAIREGHSSVVS-----FLAP 128 Query: 263 DGGDHLKSLELVPNNQGLTPFKLA 286 + H + + GLTP +LA Sbjct: 129 ESDLHHR------DASGLTPLELA 146 >1BD8-A nrPDB Length = 156 Score = 38.1 bits (87), Expect = 0.015, Method: Composition-based stats. Identities = 32/130 (24%), Positives = 57/130 (43%), Gaps = 25/130 (19%) Query: 157 GQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSE 216 G+TAL + + + LL +GAS + + T G P+ AA G Sbjct: 36 GKTALQVMMFGSTA-IALELLKQGASPNVQDTS-------------GTSPVHDAARTGFL 81 Query: 217 EIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPN 276 + +++L+EHGAD+ D G +H+ + + + L+ + H + + Sbjct: 82 DTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVS-----FLAAESDLHRR------D 130 Query: 277 NQGLTPFKLA 286 +GLTP +LA Sbjct: 131 ARGLTPLELA 140 >6CUD-A nrPDB Length = 806 Score = 38.1 bits (87), Expect = 0.015, Method: Compositional matrix adjust. Identities = 31/158 (19%), Positives = 67/158 (42%), Gaps = 13/158 (8%) Query: 486 SDGEVVP---MSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILG 542 SD +++ + A+VL + + Y + GP I + + + D+ +F L +V Sbjct: 520 SDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTV-KDIFKFMVLFIMVFFA 578 Query: 543 FASAFYIIFQTEDPDELGHFYDYPMALFSTFELFLTIIDGPANYDVDLPFMYS------- 595 F +I++ ++ + F T LF +I V L + + Sbjct: 579 FMIGMFILYSYYLGAKVNAAFTTVEESFKT--LFWSIFGLSEVTSVVLKYDHKFIENIGY 636 Query: 596 ITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWR 633 + Y + + +++LN+LIAM+ ++ + + D W+ Sbjct: 637 VLYGIYNVTMVVVLLNMLIAMINSSYQEIEDDSDVEWK 674 >2DWZ-A nrPDB Length = 231 Score = 37.7 bits (86), Expect = 0.018, Method: Compositional matrix adjust. Identities = 43/156 (27%), Positives = 65/156 (41%), Gaps = 19/156 (12%) Query: 87 SPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 SPL +AA + ++K L +G V+ G T LH AA + E A++L+E Sbjct: 75 SPLHIAASAGRDE-IVKALLVKGAHVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGA--- 130 Query: 147 FEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHP 206 P + Y+ TA+H A N+ +V LL AS + + T G P Sbjct: 131 -NPDAKDHYDA-TAMHRAAAKGNLKMVHILLFYKASTNIQDT-------------EGNTP 175 Query: 207 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHI 242 L A E + L+ GA I ++ T L + Sbjct: 176 LHLACDEERVEEAKFLVTQGASIYIENKEEKTPLQV 211 Score = 37.4 bits (85), Expect = 0.022, Method: Compositional matrix adjust. Identities = 41/157 (26%), Positives = 61/157 (38%), Gaps = 25/157 (15%) Query: 156 EGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGS 215 + +TALH A + +V LL G V+ + G PL AA G Sbjct: 39 DSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDA-------------GWSPLHIAASAGR 85 Query: 216 EEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVP 275 +EIV+ L+ GA + A + G T LH + A + + D DH + Sbjct: 86 DEIVKALLVKGAHVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYDA----- 140 Query: 276 NNQGLTPFKLAGVEGNIVMFQHLM--QKRKHIQWTYG 310 T A +GN+ M L+ + +IQ T G Sbjct: 141 -----TAMHRAAAKGNLKMVHILLFYKASTNIQDTEG 172 Score = 36.2 bits (82), Expect = 0.061, Method: Compositional matrix adjust. Identities = 31/114 (27%), Positives = 48/114 (42%), Gaps = 20/114 (17%) Query: 149 PMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSV--FHY------------ 194 P+ + G + LHIA +V+ALL +GA V+A HY Sbjct: 65 PVNDKDDAGWSPLHIAASAGRDEIVKALLVKGAHVNAVNQNGCTPLHYAASKNRHEIAVM 124 Query: 195 ------RPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHI 242 P +Y + AA G+ ++V +L+ + A QD+ GNT LH+ Sbjct: 125 LLEGGANPDAKDHYDATAMHRAAAKGNLKMVHILLFYKASTNIQDTEGNTPLHL 178 >6BPQ-A nrPDB Length = 950 Score = 37.4 bits (85), Expect = 0.026, Method: Compositional matrix adjust. Identities = 39/146 (26%), Positives = 65/146 (44%), Gaps = 25/146 (17%) Query: 514 LGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTED------------------ 555 LGP IM+Q+M+ D+ F +L AV ++ F A I + + Sbjct: 727 LGPKIIMLQRMMI-DVFFFLFLFAVWMVAFGVARQGILRKNEHRWEWIFRSVIYEPYLAM 785 Query: 556 ----PDEL-GHFYDYPMALFSTFELFLTIIDGPANYDVDLPFMYSITYAAFAIIAT-LLM 609 PD++ G Y++ FS E ++ AN P +I +++T +L+ Sbjct: 786 FGQYPDDIDGTTYNFDHCTFSGNESKPLCVELDANNQPRFPEWITIPLVCIYMLSTNILL 845 Query: 610 LNLLIAMMGDTHWRVAHERDELWRAQ 635 +NLL+AM G T V D++W+ Q Sbjct: 846 VNLLVAMFGYTVGSVQENNDQVWKFQ 871 >5JHQ-A nrPDB Length = 482 Score = 37.0 bits (84), Expect = 0.032, Method: Compositional matrix adjust. Identities = 35/118 (29%), Positives = 54/118 (45%), Gaps = 20/118 (16%) Query: 158 QTALHIAVIN---QNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVG 214 +TALH AV + + + LL +GA+V+ + + PL AA Sbjct: 356 ETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMT-------------PLHVAAERA 402 Query: 215 SEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLE 272 +++ +L +HGA + A D+LG T LH L + Q LLLSY + SL+ Sbjct: 403 HNDVMEVLHKHGAKMNALDTLGQTALHRAALAGH----LQTCRLLLSYGSDPSIISLQ 456 Score = 33.9 bits (76), Expect = 0.26, Method: Compositional matrix adjust. Identities = 17/36 (47%), Positives = 22/36 (61%) Query: 206 PLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLH 241 PL AA IV+LL++HGAD+ A+D G LH Sbjct: 205 PLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLH 240 Score = 33.1 bits (74), Expect = 0.43, Method: Compositional matrix adjust. Identities = 31/99 (31%), Positives = 43/99 (43%), Gaps = 20/99 (20%) Query: 206 PLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGG 265 PL FAA G +++V L++ GA++ A+D G LH +F LL G Sbjct: 52 PLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNAC-----SFGHAEVVSLLLCQGA 106 Query: 266 DHLKSLELVPN---NQGLTPFKLAGVEGN----IVMFQH 297 D PN N TP A ++G IV+ QH Sbjct: 107 D--------PNARDNWNYTPLHEAAIKGKIDVCIVLLQH 137 Score = 30.4 bits (67), Expect = 3.3, Method: Compositional matrix adjust. Identities = 31/95 (32%), Positives = 46/95 (48%), Gaps = 6/95 (6%) Query: 87 SPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 +PL LAA N V+ +++LL G +VH K G LH A Y + E +L++ Sbjct: 204 TPLHLAAGYNRVR-IVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGA--C 260 Query: 147 FEPMTSELYEGQTALHIAVINQNVNLVRALLARGA 181 M +L++ T LH A V + LL+ GA Sbjct: 261 VNAM--DLWQ-FTPLHEAASKNRVEVCSLLLSHGA 292 >5ET1-A nrPDB Length = 353 Score = 36.6 bits (83), Expect = 0.039, Method: Compositional matrix adjust. Identities = 39/159 (24%), Positives = 69/159 (43%), Gaps = 18/159 (11%) Query: 81 QKRIWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLME 140 Q +PL LA +E +++ L++ + H + G T LH AA + +V + Sbjct: 169 QTNNGATPLYLACQEGHLEVTKYLVQECSADPHLRAQDGMTPLHAAAQMGH-NPVLVWLV 227 Query: 141 AAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLI 200 + ++ F + + ++G TA+H A + ++ LL GA +S Sbjct: 228 SFADVSF---SEQDHDGATAMHFAASRGHTKVLSWLLLHGAEISQD-------------- 270 Query: 201 YYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTV 239 +G PL AA G E ++L +GA + +D G T Sbjct: 271 LWGGTPLHDAAENGELECCQILAVNGAGLDVRDHDGYTA 309 >3UI2-A nrPDB Length = 244 Score = 35.8 bits (81), Expect = 0.063, Method: Composition-based stats. Identities = 39/141 (27%), Positives = 63/141 (44%), Gaps = 9/141 (6%) Query: 85 WESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPE 144 +E+P AA++ + QAL +LL E +V G TAL A + + +L EA + Sbjct: 45 YETPWWTAARKADEQALSQLL--EDRDVDAVDENGRTALLFVAGLGSDKCVRLLAEAGAD 102 Query: 145 LVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSA---RATGSVFHYRPHNLIY 201 L M G TALH+A +V AL+ GA + R ++ R Sbjct: 103 LDHRDMRG----GLTALHMAAGYVRPEVVEALVELGADIEVEDERGLTALELAREILKTT 158 Query: 202 YGEHPLSFAACVGSEEIVRLL 222 +P+ F +G E+++ +L Sbjct: 159 PKGNPMQFGRRIGLEKVINVL 179 Score = 33.5 bits (75), Expect = 0.31, Method: Composition-based stats. Identities = 19/41 (46%), Positives = 25/41 (60%), Gaps = 1/41 (2%) Query: 203 GEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGN-TVLHI 242 G L F A +GS++ VRLL E GAD+ +D G T LH+ Sbjct: 77 GRTALLFVAGLGSDKCVRLLAEAGADLDHRDMRGGLTALHM 117 >6CV9-A nrPDB Length = 842 Score = 34.3 bits (77), Expect = 0.19, Method: Compositional matrix adjust. Identities = 27/148 (18%), Positives = 64/148 (43%), Gaps = 12/148 (8%) Query: 494 SFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIF-- 551 + A+VL + + Y + GP I + + + D+ +F + +V + F + ++ Sbjct: 511 AIAVVLSFSRIAYILPANESFGPLQISLGRTV-KDIFKFMVIFIMVFVAFMIGMFNLYSY 569 Query: 552 -----QTEDPDELGH-FYDYPMALFSTFELFLTIIDGPANYDVDLPFMYSITYAAFAIIA 605 Q E + F A+F E+ +I+ + ++ + + Y + + Sbjct: 570 YIGAKQNEAFTTVEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGY---VLYGVYNVTM 626 Query: 606 TLLMLNLLIAMMGDTHWRVAHERDELWR 633 +++LN+LIAM+ + + + D W+ Sbjct: 627 VIVLLNMLIAMINSSFQEIEDDADVEWK 654 >3LJN-A nrPDB Length = 364 Score = 34.3 bits (77), Expect = 0.24, Method: Compositional matrix adjust. Identities = 36/133 (27%), Positives = 59/133 (44%), Gaps = 19/133 (14%) Query: 119 GETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLA 178 G TALH+A + ++ A L L+ GQ +H+AV+ +LV AL+ Sbjct: 53 GCTALHLACKFGCVDTAKYLASVGE-------VHSLWHGQKPIHLAVMANKTDLVVALV- 104 Query: 179 RGASVSARATGSVFH---YRPHNLI------YYGEHPLSFAACVGSE--EIVRLLIEHGA 227 GA + S+ + R N I G+ L + +G E E++++L++ GA Sbjct: 105 EGAKERGQMPESLLNECDEREVNEIGSHVKHCKGQTALHWCVGLGPEYLEMIKILVQLGA 164 Query: 228 DIRAQDSLGNTVL 240 A+D T L Sbjct: 165 SPTAKDKADETPL 177 >3DEO-A nrPDB Length = 183 Score = 32.7 bits (73), Expect = 0.54, Method: Compositional matrix adjust. Identities = 19/41 (46%), Positives = 25/41 (60%), Gaps = 1/41 (2%) Query: 203 GEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGN-TVLHI 242 G L F A +GS++ VRLL E GAD+ +D G T LH+ Sbjct: 76 GRTALLFVAGLGSDKCVRLLAEAGADLDHRDMRGGLTALHM 116 Score = 30.0 bits (66), Expect = 4.2, Method: Compositional matrix adjust. Identities = 41/158 (25%), Positives = 58/158 (36%), Gaps = 52/158 (32%) Query: 85 WESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPE 144 +E+P AA++ + QAL +LL E +V G TAL A + + +L EA + Sbjct: 44 YETPWWTAARKADEQALSQLL--EDRDVDAVDENGRTALLFVAGLGSDKCVRLLAEAGAD 101 Query: 145 LVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGE 204 L M G TALH+A + RP Sbjct: 102 LDHRDMRG----GLTALHMAA--------------------------GYVRP-------- 123 Query: 205 HPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHI 242 E+V L+E GADI +D G T L + Sbjct: 124 ------------EVVEALVELGADIEVEDERGLTALEL 149 >2KXP-C nrPDB Length = 118 Score = 32.7 bits (73), Expect = 0.56, Method: Composition-based stats. Identities = 22/70 (31%), Positives = 33/70 (47%), Gaps = 13/70 (18%) Query: 164 AVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLI 223 A+ N +++ V+ +A+G V+ G G PL +AA G EI+ L+ Sbjct: 9 ALKNGDLDEVKDYVAKGEDVNRTLEG-------------GRKPLHYAADCGQLEILEFLL 55 Query: 224 EHGADIRAQD 233 GADI A D Sbjct: 56 LKGADINAPD 65 >3ZKJ-A nrPDB Length = 261 Score = 32.7 bits (73), Expect = 0.68, Method: Compositional matrix adjust. Identities = 25/78 (32%), Positives = 38/78 (48%), Gaps = 14/78 (17%) Query: 159 TALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEI 218 T L++A NQ V+ LL GA V+ + G + PL A SEE+ Sbjct: 136 TPLYLACENQQRACVKKLLESGADVN-QGKGQ-------------DSPLHAVARTASEEL 181 Query: 219 VRLLIEHGADIRAQDSLG 236 LL++ GAD +A+++ G Sbjct: 182 ACLLMDFGADTQAKNAEG 199 >1WG0-A nrPDB Length = 243 Score = 31.6 bits (70), Expect = 1.2, Method: Composition-based stats. Identities = 37/156 (23%), Positives = 59/156 (37%), Gaps = 17/156 (10%) Query: 88 PLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVF 147 PL A EN + +LL + + QK G LH + + E L+ + Sbjct: 5 PLHQACMENEFFKVQELLHSKPSLLLQKDQDGRIPLHWSVSFQAHEITSFLLSKMENVNL 64 Query: 148 EPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRP--HNLIYYGEH 205 + + G T HIA N+ +V++L R +P + + G Sbjct: 65 DDYPDD--SGWTPFHIACSVGNLEVVKSLYDRP-------------LKPDLNKITNQGVT 109 Query: 206 PLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLH 241 L A E+ + LIE+GA +R +D LH Sbjct: 110 CLHLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLH 145 >6AYG-A nrPDB Length = 558 Score = 31.6 bits (70), Expect = 1.3, Method: Compositional matrix adjust. Identities = 35/176 (19%), Positives = 78/176 (44%), Gaps = 18/176 (10%) Query: 483 LTNSDGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILG 542 LT+ D + + + +L W V+ + F + +Q + +++RFC A++ LG Sbjct: 372 LTSYDVCSILLGTSTMLVWLGVIRYLGFFAKYNLLILTLQAAL-PNVIRFCCCAAMIYLG 430 Query: 543 FASAFYIIFQTEDPDELGHFYDYPMALFSTFELFLTIIDGPANYDV--------DLPFMY 594 + +I+ LG ++D +L E ++I+G + L +++ Sbjct: 431 YCFCGWIV--------LGPYHDKFRSLNMVSECLFSLINGDDMFATFAKMQQKSYLVWLF 482 Query: 595 SITYA-AFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQVVATTVMLERKLPR 649 S Y +F + ++L+L IA++ DT+ + + + + + T + + LP Sbjct: 483 SRIYLYSFISLFIYMILSLFIALITDTYETIKQYQQDGFPETELRTFISECKDLPN 538 >3LVQ-E nrPDB Length = 497 Score = 31.2 bits (69), Expect = 1.9, Method: Compositional matrix adjust. Identities = 29/80 (36%), Positives = 40/80 (50%), Gaps = 11/80 (13%) Query: 89 LLLAAKENNVQALIKLLKF---EGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPEL 145 L LA K N QA + L+ F G + K A G TALH AALY+ + +L++ Sbjct: 175 LHLAVKVAN-QASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKG---- 229 Query: 146 VFEPMTSELYE-GQTALHIA 164 + + E G+TAL IA Sbjct: 230 --RALVGTVNEAGETALDIA 247 >1G3N-B nrPDB Length = 168 Score = 31.2 bits (69), Expect = 1.9, Method: Composition-based stats. Identities = 20/54 (37%), Positives = 30/54 (55%), Gaps = 1/54 (1%) Query: 88 PLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEA 141 PL LAAKE +++ + L+K V + G+TA +A LY E + LM+A Sbjct: 106 PLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNE-VVSLMQA 158 Score = 30.4 bits (67), Expect = 3.0, Method: Composition-based stats. Identities = 26/88 (29%), Positives = 41/88 (46%), Gaps = 18/88 (20%) Query: 157 GQTALHIAVINQNVNLVRALLARGAS--VSARATGSVFHYRPHNLIYYGEHPLSFAACVG 214 G+TAL + + N + R LL RGA+ + R +V H AA G Sbjct: 38 GRTALQVMKLG-NPEIARRLLLRGANPDLKDRTGFAVIHD---------------AARAG 81 Query: 215 SEEIVRLLIEHGADIRAQDSLGNTVLHI 242 + ++ L+E AD+ +D+ GN LH+ Sbjct: 82 FLDTLQTLLEFQADVNIEDNEGNLPLHL 109 >5MKE-A nrPDB Length = 968 Score = 30.8 bits (68), Expect = 2.1, Method: Compositional matrix adjust. Identities = 23/100 (23%), Positives = 46/100 (46%), Gaps = 5/100 (5%) Query: 528 DLMRFCWLMAVVILGFASAFYIIFQTEDPDELGHFYDYPMALFSTFELFLTIIDGPANYD 587 DL F + ++ L +A Y++F T+ D F + +F+ F + L I+ A + Sbjct: 596 DLFGFAIMFFIIFLAYAQLAYLVFGTQVDD----FSTFQECIFTQFRIILGDINF-AEIE 650 Query: 588 VDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHE 627 + I + F ++LN+ +A++ DT+ V + Sbjct: 651 EANRVLGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKSD 690 >2B0O-E nrPDB Length = 301 Score = 30.4 bits (67), Expect = 3.3, Method: Compositional matrix adjust. Identities = 29/80 (36%), Positives = 40/80 (50%), Gaps = 11/80 (13%) Query: 89 LLLAAKENNVQALIKLLKF---EGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPEL 145 L LA K N QA + L+ F G + K A G TALH AALY+ + +L++ Sbjct: 194 LHLAVKVAN-QASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKG---- 248 Query: 146 VFEPMTSELYE-GQTALHIA 164 + + E G+TAL IA Sbjct: 249 --RALVGTVNEAGETALDIA 266 >6DU8-A nrPDB Length = 805 Score = 29.6 bits (65), Expect = 4.9, Method: Compositional matrix adjust. Identities = 48/218 (22%), Positives = 91/218 (41%), Gaps = 27/218 (12%) Query: 423 LRLVGELVSIVGAVIILLVEIP---DIFR-LGVTRFFGQTILGGPFHVIIVTYA-FMVLV 477 LR + + +I+ V+ILL + IFR L V R G+ +L P TYA F L Sbjct: 379 LRYLSSIWNILDLVVILLSIVAVGFHIFRTLEVNRLMGK-LLQQP-----NTYADFEFLA 432 Query: 478 TMVMRLTNSDGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMA 537 + N + + L W + + + + + + + D++ F + Sbjct: 433 FWQTQYNNMN------AVNLFFAWIKIFKYISFNKTMTQLSSTLARCA-KDILGFAVMFF 485 Query: 538 VVILGFASAFYIIFQTEDPDELGHFYDYPMALFSTFELFLTIIDGPANYDVDLPFMYSIT 597 +V +A Y++F T+ + +F + +F+ F + L D A D + Sbjct: 486 IVFFAYAQLGYLLFGTQ----VENFSTFIKCIFTQFRIILGDFDYNA-IDNANRILGPAY 540 Query: 598 YAAFAIIATLLMLNLLIAMMGDTHWRVAHE----RDEL 631 + + ++LN+ +A++ DT+ V E +DEL Sbjct: 541 FVTYVFFVFFVLLNMFLAIINDTYSEVKEELAGQKDEL 578 >5U0K-A nrPDB Length = 141 Score = 29.6 bits (65), Expect = 5.6, Method: Compositional matrix adjust. Identities = 22/66 (33%), Positives = 31/66 (46%), Gaps = 1/66 (1%) Query: 76 QNLLQQKRIWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAA 135 +NL Q LL AA +V AL + ++ QK TALH+AA ++E Sbjct: 16 ENLYFQSMKTVVNLLFAAYSGDVSAL-RRFALSAMDMEQKDYDSRTALHVAAAEGHIEVV 74 Query: 136 MVLMEA 141 L+EA Sbjct: 75 KFLIEA 80 >5UIL-A nrPDB Length = 405 Score = 29.3 bits (64), Expect = 5.9, Method: Compositional matrix adjust. Identities = 14/38 (36%), Positives = 23/38 (60%) Query: 202 YGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTV 239 YG P+ AA G+ E+++ L+ GA+I ++ G TV Sbjct: 310 YGWSPVIVAAYHGNIELIKWLVSKGANINDRNYKGTTV 347 >5UQE-A nrPDB Length = 520 Score = 28.9 bits (63), Expect = 8.2, Method: Compositional matrix adjust. Identities = 18/54 (33%), Positives = 27/54 (50%), Gaps = 1/54 (1%) Query: 89 LLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAA 142 LL AA +V AL + ++ Q+ TALH+AA ++E L+EA Sbjct: 421 LLFAAYTGDVSAL-RRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEAC 473 >6BWI-A nrPDB Length = 977 Score = 28.9 bits (63), Expect = 8.3, Method: Compositional matrix adjust. Identities = 14/31 (45%), Positives = 19/31 (61%) Query: 605 ATLLMLNLLIAMMGDTHWRVAHERDELWRAQ 635 A +L++NLLIAM T +V D W+AQ Sbjct: 832 ANILLVNLLIAMFSYTFGKVQGNSDLYWKAQ 862 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6E2G-A nrPDB 1095 0.0 6BOA-A nrPDB 1041 0.0 6DMR-A nrPDB 959 0.0 6BBJ-A nrPDB 602 e-172 6C8G-A nrPDB 597 e-171 5IRX-A nrPDB 590 e-169 6OO7-A nrPDB 575 e-164 5HI9-A nrPDB 574 e-164 6BO5-A nrPDB 570 e-163 5AN8-A nrPDB 570 e-162 6DVZ-A nrPDB 564 e-161 6MHW-A nrPDB 548 e-156 2RFA-A nrPDB 296 2e-80 2ETB-A nrPDB 213 3e-55 2F37-A nrPDB 208 5e-54 6AUN-A nrPDB 187 1e-47 3W9G-A nrPDB 186 4e-47 4N5Q-A nrPDB 185 5e-47 5AQ9-A nrPDB 184 1e-46 4DX2-A nrPDB 183 2e-46 6MWQ-A nrPDB 181 8e-46 5AQ7-A nrPDB 181 1e-45 5AQB-A nrPDB 181 1e-45 5AQA-A nrPDB 179 3e-45 6FES-A nrPDB 177 2e-44 5MIO-C nrPDB 176 5e-44 2NYJ-A nrPDB 175 7e-44 6BY9-A nrPDB 174 1e-43 3B7B-A nrPDB 174 1e-43 5H76-A nrPDB 174 1e-43 4OAU-C nrPDB 169 5e-42 4O1O-A nrPDB 164 1e-40 6G1K-A nrPDB 164 1e-40 5GP7-A nrPDB 152 4e-37 4NIK-A nrPDB 138 7e-33 4Z68-A nrPDB 137 2e-32 5CBO-A nrPDB 125 8e-29 Sequences not found previously or not previously below threshold: 5Z96-A nrPDB 148 9e-36 5HKP-A nrPDB 136 3e-32 5JHQ-A nrPDB 136 3e-32 2DWZ-A nrPDB 134 1e-31 5ET1-A nrPDB 117 2e-26 3EU9-A nrPDB 107 2e-23 4OT9-A nrPDB 102 9e-22 3ZKJ-A nrPDB 94 1e-19 6CUD-A nrPDB 94 2e-19 1WG0-A nrPDB 92 9e-19 1BD8-A nrPDB 87 3e-17 1BLX-B nrPDB 79 9e-15 6CV9-A nrPDB 78 1e-14 1G3N-B nrPDB 78 2e-14 6EMK-G nrPDB 76 6e-14 3LJN-A nrPDB 75 1e-13 5D68-A nrPDB 71 3e-12 3UI2-A nrPDB 70 4e-12 3EHQ-A nrPDB 70 5e-12 3T9K-A nrPDB 70 5e-12 3DEO-A nrPDB 69 7e-12 2KXP-C nrPDB 69 8e-12 5DND-A nrPDB 67 2e-11 4BSZ-B nrPDB 61 2e-09 5U0K-A nrPDB 59 9e-09 6BPQ-A nrPDB 57 3e-08 6BWF-A nrPDB 56 7e-08 5U0J-A nrPDB 55 2e-07 6DJS-A nrPDB 54 2e-07 5UQE-A nrPDB 54 2e-07 3LVQ-E nrPDB 53 5e-07 2B0O-E nrPDB 53 5e-07 1D9S-A nrPDB 52 7e-07 5Z1W-A nrPDB 49 7e-06 6DU8-A nrPDB 49 7e-06 2A5E-A nrPDB 48 1e-05 1DCQ-A nrPDB 47 3e-05 5OEO-C nrPDB 46 7e-05 5UIL-A nrPDB 45 1e-04 5T4D-A nrPDB 45 1e-04 5MKE-A nrPDB 45 1e-04 5WPT-A nrPDB 45 2e-04 6E7Z-A nrPDB 43 6e-04 6D1W-A nrPDB 42 7e-04 6AYG-A nrPDB 41 0.002 4XD0-A nrPDB 39 0.006 4DXW-A nrPDB 38 0.016 6BWI-A nrPDB 38 0.016 3JB9-c nrPDB 37 0.035 4GX0-A nrPDB 31 1.9 2GBW-A nrPDB 31 2.3 2QHX-A nrPDB 30 3.5 2BFA-A nrPDB 30 3.5 3CO4-A nrPDB 30 3.7 2DI3-A nrPDB 30 4.4 4BGN-A nrPDB 29 6.0 2FT0-A nrPDB 29 6.1 1Y1U-A nrPDB 29 7.1 >6E2G-A nrPDB Length = 727 Score = 1095 bits (2831), Expect = 0.0, Method: Composition-based stats. Identities = 727/727 (100%), Positives = 727/727 (100%) Query: 41 MGWSLPKEKGLILCLWNKFCRWFHRRESWAQSRDEQNLLQQKRIWESPLLLAAKENNVQA 100 MGWSLPKEKGLILCLWNKFCRWFHRRESWAQSRDEQNLLQQKRIWESPLLLAAKENNVQA Sbjct: 1 MGWSLPKEKGLILCLWNKFCRWFHRRESWAQSRDEQNLLQQKRIWESPLLLAAKENNVQA 60 Query: 101 LIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTA 160 LIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTA Sbjct: 61 LIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTA 120 Query: 161 LHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVR 220 LHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVR Sbjct: 121 LHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVR 180 Query: 221 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGL 280 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGL Sbjct: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGL 240 Query: 281 TPFKLAGVEGNIVMFQHLMQKRKHIQWTYGPLTSTLYDLTEIDSSGDDQSLLELIVTTKK 340 TPFKLAGVEGNIVMFQHLMQKRKHIQWTYGPLTSTLYDLTEIDSSGDDQSLLELIVTTKK Sbjct: 241 TPFKLAGVEGNIVMFQHLMQKRKHIQWTYGPLTSTLYDLTEIDSSGDDQSLLELIVTTKK 300 Query: 341 REARQILDQTPVKELVSLKWKRYGRPYFCVLGAIYVLYIICFTMCCVYRPLKPRITNRTN 400 REARQILDQTPVKELVSLKWKRYGRPYFCVLGAIYVLYIICFTMCCVYRPLKPRITNRTN Sbjct: 301 REARQILDQTPVKELVSLKWKRYGRPYFCVLGAIYVLYIICFTMCCVYRPLKPRITNRTN 360 Query: 401 PRDNTLLQQKLLQEAYVTPKDDLRLVGELVSIVGAVIILLVEIPDIFRLGVTRFFGQTIL 460 PRDNTLLQQKLLQEAYVTPKDDLRLVGELVSIVGAVIILLVEIPDIFRLGVTRFFGQTIL Sbjct: 361 PRDNTLLQQKLLQEAYVTPKDDLRLVGELVSIVGAVIILLVEIPDIFRLGVTRFFGQTIL 420 Query: 461 GGPFHVIIVTYAFMVLVTMVMRLTNSDGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIM 520 GGPFHVIIVTYAFMVLVTMVMRLTNSDGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIM Sbjct: 421 GGPFHVIIVTYAFMVLVTMVMRLTNSDGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIM 480 Query: 521 IQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPDELGHFYDYPMALFSTFELFLTII 580 IQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPDELGHFYDYPMALFSTFELFLTII Sbjct: 481 IQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPDELGHFYDYPMALFSTFELFLTII 540 Query: 581 DGPANYDVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQVVATT 640 DGPANYDVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQVVATT Sbjct: 541 DGPANYDVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQVVATT 600 Query: 641 VMLERKLPRCLWPRSGICGREYGLGDRWFLRVEDRQDLNRQRIRRYAQAFQQQDDLYSED 700 VMLERKLPRCLWPRSGICGREYGLGDRWFLRVEDRQDLNRQRIRRYAQAFQQQDDLYSED Sbjct: 601 VMLERKLPRCLWPRSGICGREYGLGDRWFLRVEDRQDLNRQRIRRYAQAFQQQDDLYSED 660 Query: 701 LEKDSGEKLEMARPFGAYLSFPTPSVSRSTSRSSTNWDRLRQGALRKDLQGIINRGLEDG 760 LEKDSGEKLEMARPFGAYLSFPTPSVSRSTSRSSTNWDRLRQGALRKDLQGIINRGLEDG Sbjct: 661 LEKDSGEKLEMARPFGAYLSFPTPSVSRSTSRSSTNWDRLRQGALRKDLQGIINRGLEDG 720 Query: 761 EGWEYQI 767 EGWEYQI Sbjct: 721 EGWEYQI 727 >6BOA-A nrPDB Length = 742 Score = 1041 bits (2692), Expect = 0.0, Method: Composition-based stats. Identities = 649/728 (89%), Positives = 691/728 (94%), Gaps = 4/728 (0%) Query: 41 MGWSLPKEKGLILCLWNKFCRWFHRRESWAQSRDEQNLLQQKRIWESPLLLAAKENNVQA 100 MG SLPKEKGLILCLW+KFCRWF RRESWAQSRDEQNLLQQKRIWESPLLLAAK+N+VQA Sbjct: 1 MGLSLPKEKGLILCLWSKFCRWFQRRESWAQSRDEQNLLQQKRIWESPLLLAAKDNDVQA 60 Query: 101 LIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTA 160 L KLLK+E C+VHQ+GAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTA Sbjct: 61 LNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTA 120 Query: 161 LHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVR 220 LHIAV+NQN+NLVRALLAR ASVSARATG+ F P NLIY+GEHPLSFAACV SEEIVR Sbjct: 121 LHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVR 180 Query: 221 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD-GGDHLKSLELVPNNQG 279 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD GDHL+ L+LVPN+QG Sbjct: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDRHGDHLQPLDLVPNHQG 240 Query: 280 LTPFKLAGVEGNIVMFQHLMQKRKHIQWTYGPLTSTLYDLTEIDSSGDDQSLLELIVTTK 339 LTPFKLAGVEGN VMFQHLMQKRKH QWTYGPLTSTLYDLTEIDSSGD+QSLLELI+TTK Sbjct: 241 LTPFKLAGVEGNTVMFQHLMQKRKHTQWTYGPLTSTLYDLTEIDSSGDEQSLLELIITTK 300 Query: 340 KREARQILDQTPVKELVSLKWKRYGRPYFCVLGAIYVLYIICFTMCCVYRPLKPRITNRT 399 KREARQILDQTPVKELVSLKWKRYGRPYFC+LGAIY+LYIICFTMCC+YRPLKPR NRT Sbjct: 301 KREARQILDQTPVKELVSLKWKRYGRPYFCMLGAIYLLYIICFTMCCIYRPLKPRTNNRT 360 Query: 400 NPRDNTLLQQKLLQEAYVTPKDDLRLVGELVSIVGAVIILLVEIPDIFRLGVTRFFGQTI 459 +PRDNTLLQQKLLQEAY+TPKDD+RLVGELV+++GA+IILLVE+PDIFR+GVTRFFGQTI Sbjct: 361 SPRDNTLLQQKLLQEAYMTPKDDIRLVGELVTVIGAIIILLVEVPDIFRMGVTRFFGQTI 420 Query: 460 LGGPFHVIIVTYAFMVLVTMVMRLTNSDGEVVPMSFALVLGWCNVMYFARGFQMLGPFTI 519 LGGPFHV+I+TYAFMVLVTMVMRL ++ GEVVPMSFALVLGWCNVMYFA GFQMLGPFTI Sbjct: 421 LGGPFHVLIITYAFMVLVTMVMRLISASGEVVPMSFALVLGWCNVMYFAEGFQMLGPFTI 480 Query: 520 MIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPDELGHFYDYPMALFSTFELFLTI 579 MIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDP+ELGHFYDYPMALFSTFELFLTI Sbjct: 481 MIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPEELGHFYDYPMALFSTFELFLTI 540 Query: 580 IDGPANYDVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQVVAT 639 IDGPANY+VDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQ+VAT Sbjct: 541 IDGPANYNVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVAT 600 Query: 640 TVMLERKLPRCLWPRSGICGREYGLGDRWFLRVEDRQDLNRQRIRRYAQAFQQQDDLYSE 699 TVMLERKLPRCLWPRSGICGREYGLGDRWFLRVEDRQDLNRQRI+RYAQAF + SE Sbjct: 601 TVMLERKLPRCLWPRSGICGREYGLGDRWFLRVEDRQDLNRQRIQRYAQAFHTRG---SE 657 Query: 700 DLEKDSGEKLEMARPFGAYLSFPTPSVSRSTSRSSTNWDRLRQGALRKDLQGIINRGLED 759 DL+KDS EKLE+ PF +LS P PSVSRSTSRSS NW+RLRQG LR+DL+GIINRGLED Sbjct: 658 DLDKDSVEKLELGCPFSPHLSLPMPSVSRSTSRSSANWERLRQGTLRRDLRGIINRGLED 717 Query: 760 GEGWEYQI 767 GE WEYQI Sbjct: 718 GESWEYQI 725 >6DMR-A nrPDB Length = 730 Score = 959 bits (2478), Expect = 0.0, Method: Composition-based stats. Identities = 541/734 (73%), Positives = 610/734 (83%), Gaps = 24/734 (3%) Query: 41 MGWSLPKEKGLILCLWNKFCRWFHRRESWAQSRDEQNLLQQKRIWESPLLLAAKENNVQA 100 MG PK KG L W + W Q RD N+LQQ+RI +SPLL AAKEN+++ Sbjct: 1 MGACPPKAKGPWAQLQKLLISWPVGEQDWEQYRDRVNMLQQERIRDSPLLQAAKENDLRL 60 Query: 101 LIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTA 160 L LL + C+ Q+GA+GETALH+AALYDNLEAA +LMEAAPEL EP E + GQTA Sbjct: 61 LKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTA 120 Query: 161 LHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVR 220 LHIAV+NQN+NLVRALLARGASVSARATG+ F PHNLIYYGEHPLSFAACVGSEEIVR Sbjct: 121 LHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVR 180 Query: 221 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD-GGDHLKSLELVPNNQG 279 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD DHL+SLELVPN+QG Sbjct: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLELVPNHQG 240 Query: 280 LTPFKLAGVEGNIVMFQHLMQKRKHIQWTYGPLTSTLYDLTEIDSSGDDQSLLELIVTTK 339 LTPFKLAGVEGN VMFQHLMQKRKH+QWT GPLTSTLYDLTEIDS G++ S LEL+V++K Sbjct: 241 LTPFKLAGVEGNTVMFQHLMQKRKHVQWTCGPLTSTLYDLTEIDSWGEELSFLELVVSSK 300 Query: 340 KREARQILDQTPVKELVSLKWKRYGRPYFCVLGAIYVLYIICFTMCCVYRPLKPRITNRT 399 KREARQIL+QTPVKELVS KWK+YGRPYFCVL ++Y+LY+ICFT CC+YRPLK R NRT Sbjct: 301 KREARQILEQTPVKELVSFKWKKYGRPYFCVLASLYILYMICFTTCCIYRPLKLRDDNRT 360 Query: 400 NPRDNTLLQQKLLQEAYVTPKDDLRLVGELVSIVGAVIILLVEIPDIFRLGVTRFFGQTI 459 +PRD T+LQQKLLQEAYVT +D++RLVGELV++ GAVIILL+EIPDIFR+G +R+FGQTI Sbjct: 361 DPRDITILQQKLLQEAYVTHQDNIRLVGELVTVTGAVIILLLEIPDIFRVGASRYFGQTI 420 Query: 460 LGGPFHVIIVTYAFMVLVTMVMRLTNSDGEVVPMSFALVLGWCNVMYFARGFQMLGPFTI 519 LGGPFHVII+TYA +VL+TMVMRLTN +GEVVP+SFALVLGWC+VMYFARGFQMLGPFTI Sbjct: 421 LGGPFHVIIITYASLVLLTMVMRLTNMNGEVVPLSFALVLGWCSVMYFARGFQMLGPFTI 480 Query: 520 MIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPDELGHFYDYPMALFSTFELFLTI 579 MIQKMIFGDLMRFCWLMAVVILGFASAF+I FQTEDP+ LG F DYP ALFSTFELFLTI Sbjct: 481 MIQKMIFGDLMRFCWLMAVVILGFASAFHITFQTEDPNNLGEFSDYPTALFSTFELFLTI 540 Query: 580 IDGPANYDVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQVVAT 639 IDGPANY VDLPFMY ITYAAFAIIATLLMLNL IAMMGDTHWRVA ERDELWRAQVVAT Sbjct: 541 IDGPANYSVDLPFMYCITYAAFAIIATLLMLNLFIAMMGDTHWRVAQERDELWRAQVVAT 600 Query: 640 TVMLERKLPRCLWPRSGICGREYGLGDRWFLRVEDRQDLNRQRIRRYAQAFQQQDDLYSE 699 TVMLERK+PR LWPRSGICG EYGLGDRWFLRVE+ D N R+ RY +AF+ D Sbjct: 601 TVMLERKMPRFLWPRSGICGYEYGLGDRWFLRVENHHDQNPLRVLRYVEAFKCSD----- 655 Query: 700 DLEKDSGEKLEMARPFG--------AYLSFPTPSVSRSTSRSSTN---WDRLRQGALRKD 748 ++D E+L RP A ++F TPS+SR+TS+SS + W+ LR+ L Sbjct: 656 --KEDGQEQLSEKRPSTVESGMLSRASVAFQTPSLSRTTSQSSNSHRGWEILRRNTL--- 710 Query: 749 LQGIINRGLEDGEG 762 G +N GL+ GEG Sbjct: 711 --GHLNLGLDLGEG 722 >6BBJ-A nrPDB Length = 868 Score = 602 bits (1551), Expect = e-172, Method: Composition-based stats. Identities = 194/641 (30%), Positives = 310/641 (48%), Gaps = 83/641 (12%) Query: 88 PLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAAL---YDNLEAAMVLME---- 140 P LLA K+ + + + G+T L A + + +L++ Sbjct: 167 PFLLAQKKRLTDEEFR-----------EASTGKTCLTKALMNLNGGKNDTIPMLIDIAEK 215 Query: 141 --AAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHN 198 E + P Y GQTALHIA+ + + V L+ +GA V A+A G F + Sbjct: 216 TGNLREFINSPFRDVYYRGQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEG 275 Query: 199 -LIYYGEHPLSFAACVGSEEIVRLLIEH---GADIRAQDSLGNTVLHILI-----LQPNK 249 Y+GE PLS AAC +IV L E+ ADIR QDS GNTVLH L+ + N Sbjct: 276 GYFYFGELPLSLAACTNQPDIVHYLTENAHKKADIRRQDSRGNTVLHALVAIADNTRENT 335 Query: 250 TFACQMYNLLLSYDGGDHL-KSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQ-------- 300 F ++Y+LL+ + SLE + NN ++P +A G I +FQH+++ Sbjct: 336 KFVTKVYDLLVIKCVKLYPDSSLEAIFNNDSMSPLMMAAKLGKIGIFQHIIRLEIKDEEA 395 Query: 301 ---KRKHIQWTYGPLTSTLYDLTEIDSSGDDQSLLELIVTTKKREAR-QILDQTPVKELV 356 RK W YGP+ S+LYDL+ +D+ G++ S+LE++V K E R ++L P+ EL+ Sbjct: 396 RHLSRKFRDWAYGPVYSSLYDLSMLDTCGEEVSVLEILVYNSKVENRHEMLAVEPINELL 455 Query: 357 SLKWKRYGRPYFCVLGAIYVLYIICFTMCCVYRPLKPRITNRTNPRDNTLLQQKLLQEAY 416 KW+++G F + Y++ +I FT+ YRP+ + T P Y Sbjct: 456 RDKWQKFGAVSFYISVVSYLIAMIIFTLIAYYRPM-----DGTPPY------------PY 498 Query: 417 VTPKDDLRLVGELVSIVGAVIILLVEIPDIFRLGVTRFFGQTILGGPFHVIIVTYAFMVL 476 T D +RL GE+V+++ V+ + I D+F + G F ++ Y+ +V+ Sbjct: 499 RTTMDYMRLAGEIVTLLTGVVFFITNIKDLFMKK-CPGVNSLFIDGSFQLLYFIYSVLVI 557 Query: 477 VTMVMRLTNSDGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLM 536 +T V+ L + + M FALVLGW N +YF RG ++ G ++IM+QK++F DL RF + Sbjct: 558 ITAVLYLVGIESYLAVMVFALVLGWMNALYFTRGLKLTGTYSIMLQKILFKDLFRFLLVY 617 Query: 537 AVVILGFASAFYIIFQTEDPDEL-------GHFYDYPMA---------LFSTFELFLTII 580 + ++G+ASA + E +YP L F+L + + Sbjct: 618 LLFMIGYASALVSLLNPCTSQESCIETSSNCTVPEYPSCRDSSTFSKFLLDLFKLTIGMG 677 Query: 581 DGPANYDVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQVVATT 640 D P ++ I + I+ +L+LN+LIA+MG+T +V+ E ++W+ Q T Sbjct: 678 DLEMINSAKYPAVFIILLVTYIILTFVLLLNMLIALMGETVGQVSKESKQIWKLQWATTI 737 Query: 641 VMLERKLPRCLWP--RSG----ICGREYGLGD-RWFLRVED 674 + +ER P C+ RSG + G D RW RV++ Sbjct: 738 LDIERSFPVCMRKAFRSGEMVTVGKNLDGTPDRRWCFRVDE 778 >6C8G-A nrPDB Length = 675 Score = 597 bits (1539), Expect = e-171, Method: Composition-based stats. Identities = 194/641 (30%), Positives = 310/641 (48%), Gaps = 83/641 (12%) Query: 88 PLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAAL---YDNLEAAMVLME---- 140 P LLA K+ + + + G+T L A + + +L++ Sbjct: 36 PFLLAQKKRLTDEEFR-----------EASTGKTCLTKALMNLNGGKNDTIPMLIDIAEK 84 Query: 141 --AAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHN 198 E + P Y GQTALHIA+ + + V L+ +GA V A+A G F + Sbjct: 85 TGNLREFINSPFRDVYYRGQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEG 144 Query: 199 -LIYYGEHPLSFAACVGSEEIVRLLIEH---GADIRAQDSLGNTVLHILI-----LQPNK 249 Y+GE PLS AAC +IV L E+ ADIR QDS GNTVLH L+ + N Sbjct: 145 GYFYFGELPLSLAACTNQPDIVHYLTENAHKKADIRRQDSRGNTVLHALVAIADNTRENT 204 Query: 250 TFACQMYNLLLSYDGGDHL-KSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQ-------- 300 F ++Y+LL+ + SLE + NN ++P +A G I +FQH+++ Sbjct: 205 KFVTKVYDLLVIKCVKLYPDSSLEAIFNNDSMSPLMMAAKLGKIGIFQHIIRLEIKDEEA 264 Query: 301 ---KRKHIQWTYGPLTSTLYDLTEIDSSGDDQSLLELIVTTKKREAR-QILDQTPVKELV 356 RK W YGP+ S+LYDL+ +D+ G++ S+LE++V K E R ++L P+ EL+ Sbjct: 265 RHLSRKFRDWAYGPVYSSLYDLSMLDTCGEEVSVLEILVYNSKVENRHEMLAVEPINELL 324 Query: 357 SLKWKRYGRPYFCVLGAIYVLYIICFTMCCVYRPLKPRITNRTNPRDNTLLQQKLLQEAY 416 KW+++G F + Y++ +I FT+ YRP+ + T P Y Sbjct: 325 RDKWQKFGAVSFYISVVSYLIAMIIFTLIAYYRPM-----DGTPPY------------PY 367 Query: 417 VTPKDDLRLVGELVSIVGAVIILLVEIPDIFRLGVTRFFGQTILGGPFHVIIVTYAFMVL 476 T D +RL GE+V+++ V+ + I D+F + G F ++ Y+ +V+ Sbjct: 368 RTTMDYMRLAGEIVTLLTGVVFFITNIKDLFMKK-CPGVNSLFIDGSFQLLYFIYSVLVI 426 Query: 477 VTMVMRLTNSDGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLM 536 +T V+ L + + M FALVLGW N +YF RG ++ G ++IM+QK++F DL RF + Sbjct: 427 ITAVLYLVGIESYLAVMVFALVLGWMNALYFTRGLKLTGTYSIMLQKILFKDLFRFLLVY 486 Query: 537 AVVILGFASAFYIIFQTEDPDEL-------GHFYDYPMA---------LFSTFELFLTII 580 + ++G+ASA + E +YP L F+L + + Sbjct: 487 LLFMIGYASALVSLLNPCTSQESCIETSSQCTVPEYPSCRDSSTFSKFLLDLFKLTIGMG 546 Query: 581 DGPANYDVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQVVATT 640 D P ++ I + I+ +L+LN+LIA+MG+T +V+ E ++W+ Q T Sbjct: 547 DLEMINSAKYPAVFIILLVTYIILTFVLLLNMLIALMGETVGQVSKESKQIWKLQWATTI 606 Query: 641 VMLERKLPRCLWP--RSG----ICGREYGLGD-RWFLRVED 674 + +ER P C+ RSG + G D RW RV++ Sbjct: 607 LDIERSFPVCMRKAFRSGEMVTVGKNLDGTPDRRWCFRVDE 647 >5IRX-A nrPDB Length = 636 Score = 590 bits (1522), Expect = e-169, Method: Composition-based stats. Identities = 183/597 (30%), Positives = 286/597 (47%), Gaps = 64/597 (10%) Query: 117 AMGETALHIAALY---DNLEAAMVLMEAA------PELVFEPMTSELYEGQTALHIAVIN 167 G+T L A L + +L++ A + V T Y+GQTALHIA+ Sbjct: 47 ETGKTCLLKAMLNLHNGQNDTIALLLDVARKTDSLKQFVNASYTDSYYKGQTALHIAIER 106 Query: 168 QNVNLVRALLARGASVSARATGSVFHYRPHN-LIYYGEHPLSFAACVGSEEIVRLLIEH- 225 +N+ LV L+ GA V A A G F Y+GE PLS AAC IV+ L+++ Sbjct: 107 RNMTLVTLLVENGADVQAAANGDFFKKTKGRPGFYFGELPLSLAACTNQLAIVKFLLQNS 166 Query: 226 --GADIRAQDSLGNTVLHILILQPNKT-----FACQMYNLLLSYDGGDH-LKSLELVPNN 277 ADI A+DS+GNTVLH L+ + T F MYN +L H LE + N Sbjct: 167 WQPADISARDSVGNTVLHALVEVADNTVDNTKFVTSMYNEILILGAKLHPTLKLEEITNR 226 Query: 278 QGLTPFKLAGVEGNIVMFQHLMQK-----------RKHIQWTYGPLTSTLYDLTEIDSSG 326 +GLTP LA G I + +++Q+ RK +W YGP+ S+LYDL+ ID+ Sbjct: 227 KGLTPLALAASSGKIGVLAYILQREIHEPECRHLSRKFTEWAYGPVHSSLYDLSCIDTC- 285 Query: 327 DDQSLLELIVTT--KKREARQILDQTPVKELVSLKWKRYGRPYFCVLGAIYVLYIICFTM 384 + S+LE+I + + +L P+ L+ KW R+ + F +Y LY+I FT Sbjct: 286 EKNSVLEVIAYSSSETPNRHDMLLVEPLNRLLQDKWDRFVKRIFYFNFFVYCLYMIIFTA 345 Query: 385 CCVYRPLKPRITNRTNPRDNTLLQQKLLQEAYVTPKDDLRLVGELVSIVGAVIILLVEIP 444 YRP++ L KL T D R+ GE++S+ G V I Sbjct: 346 AAYYRPVEG------------LPPYKLKN----TVGDYFRVTGEILSVSGGVYFFFRGIQ 389 Query: 445 DIFRLGVTRFFGQTILGGPFHVIIVTYAFMVLVTMVMRLTNSDGEVVPMSFALVLGWCNV 504 + + + ++ + +LV++V+ + V M F+L +GW N+ Sbjct: 390 YFLQRRPS--LKSLFVDSYSEILFFVQSLFMLVSVVLYFSQRKEYVASMVFSLAMGWTNM 447 Query: 505 MYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPDELGHFYD 564 +Y+ RGFQ +G + +MI+KMI DL RF ++ V + GF++A + + + Y Sbjct: 448 LYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYLVFLFGFSTAVVTLI---EDGKYNSLYS 504 Query: 565 YPMALFSTFELFLTIIDGPANYDVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRV 624 + LF F + + ++ NYD F+ I A+ I+ +L+LN+LIA+MG+T ++ Sbjct: 505 TCLELFK-FTIGMGDLEFTENYDFKAVFI--ILLLAYVILTYILLLNMLIALMGETVNKI 561 Query: 625 AHERDELWRAQVVATTVMLERKLPRCLWP--RSG----ICGREYGLGD-RWFLRVED 674 A E +W+ Q T + E+ +C+ RSG + G D RW RV++ Sbjct: 562 AQESKNIWKLQRAITILDTEKSFLKCMRKAFRSGKLLQVGFTPDGKDDYRWCFRVDE 618 Score = 40.5 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 32/190 (16%), Positives = 62/190 (32%), Gaps = 19/190 (10%) Query: 84 IWESPLLLAAKENNVQALIKLLKF--EGCEVHQKGAMGETALHIAA-----LYDNLEAAM 136 E PL LAA N + + LL+ + ++ + ++G T LH DN + Sbjct: 142 FGELPLSLAACTNQLAIVKFLLQNSWQPADISARDSVGNTVLHALVEVADNTVDNTKFVT 201 Query: 137 VLMEA----APELVFEPMTSE--LYEGQTALHIAVINQNVNLVRALLARGASVSARATGS 190 + +L E +G T L +A + + ++ +L R + Sbjct: 202 SMYNEILILGAKLHPTLKLEEITNRKGLTPLALAASSGKIGVLAYILQR--EIHEPECRH 259 Query: 191 VFHYRPHNLIYYGEHPLSFAACVGSEEIVRLL----IEHGADIRAQDSLGNTVLHILILQ 246 + L +C+ + E +L D L L+ L+ Sbjct: 260 LSRKFTEWAYGPVHSSLYDLSCIDTCEKNSVLEVIAYSSSETPNRHDMLLVEPLNRLLQD 319 Query: 247 PNKTFACQMY 256 F +++ Sbjct: 320 KWDRFVKRIF 329 >6OO7-A nrPDB Length = 786 Score = 575 bits (1481), Expect = e-164, Method: Composition-based stats. Identities = 176/636 (27%), Positives = 299/636 (47%), Gaps = 75/636 (11%) Query: 95 ENNVQALIKLLKFEGCEVHQKGAMGETALHIAAL--YDNLEAA-MVLMEAAPE------L 145 ++ L + K+ + +G+ G+T L A L D + A L+E + L Sbjct: 91 AGLLEYLRRTSKYLTDSEYTEGSTGKTCLMKAVLNLQDGVNACIQPLLEIDRDSGNPQPL 150 Query: 146 VFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEH 205 V T E Y G +ALHIA+ +++ V+ L+ GA+V A+A G F Y+GE Sbjct: 151 VNAQCTDEYYRGHSALHIAIEKRSLQCVKLLVENGANVHAKACGHFFQKNQDTCFYFGEL 210 Query: 206 PLSFAACVGSEEIVRLLIEHG---ADIRAQDSLGNTVLHILIL-----QPNKTFACQMYN 257 PLS AAC ++V L+E+ A ++AQDSLGNTVLH L++ N +MY+ Sbjct: 211 PLSLAACTKQWDVVNYLLENPHQPASLQAQDSLGNTVLHALVMIADDSAENSALVVRMYD 270 Query: 258 LLLSYDGGD-HLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQK----------RKHIQ 306 LL LE +PN +GLTP KLA EG I +F+H++Q+ RK + Sbjct: 271 GLLQAGARLCPNVQLEGIPNLEGLTPLKLAAKEGKIEIFKHILQREFSAPCQSLSRKFTE 330 Query: 307 WTYGPLTSTLYDLTEIDSSGDDQSLLELIVTTKKREAR-QILDQTPVKELVSLKWKRYGR 365 W YGP+ +LYDL +DS ++ S+LE+I + R +++ P+ +L+ KW R Sbjct: 331 WCYGPVRVSLYDLASVDS-WEENSVLEIIAFHSRSPHRHRMVVLEPLNKLLQAKWDRLI- 388 Query: 366 PYFCVLGAIYVLYIICFTMCCVYRPLKPRITNRTNPRDNTLLQQKLLQEAYVTPKDDLRL 425 P FC Y++Y++ FT ++P L+++ T + + L Sbjct: 389 PRFCFNFLCYLVYMLIFTAVAYHQP---------------ALEKQGFPPLKATAGNSMLL 433 Query: 426 VGELVSIVGAVIILLVEIPDIFRLGVTRFFGQTILGGPFHVIIVTYAFMVLVTMVMRLTN 485 +G ++ ++G V +LL ++ +R + F + + ++ + A + +++ V+ Sbjct: 434 LGHILILLGGVYLLLGQLWYFWRRRL--FIWISFMDSYSEILFLLQALLTVLSQVLCFLA 491 Query: 486 SDGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFAS 545 + + + +L +GW N++Y+ RGFQ G +++MI+K+I DL+RF + V + GFA Sbjct: 492 IEWYLPLLVSSLAMGWTNLLYYTRGFQHTGIYSVMIEKVILRDLLRFLLVYLVFLFGFAV 551 Query: 546 AFYIIFQTEDPDELG-----------------HFYDYPMALFSTFELF-LTIIDGPANYD 587 A + + Y L ++ ELF TI G + Sbjct: 552 ALVSLSREAQNSRTPAGPNATEVGQPGAGQEDEAPPYRSILDASLELFKFTIGMGELAFQ 611 Query: 588 VDLPFMY--SITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQVVATTVMLER 645 L F + A+ ++ +L+LN+LIA+M +T VA + +W+ Q + + +E Sbjct: 612 EQLRFRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNSVATDSWSIWKLQKAISVLEMEN 671 Query: 646 KLPRCLWPRSG------ICGREYGLGD-RWFLRVED 674 C + + R G D RW RV + Sbjct: 672 GYWWCRRKKQRAGVMLTVGTRPDGSPDERWCFRVGE 707 >5HI9-A nrPDB Length = 770 Score = 574 bits (1480), Expect = e-164, Method: Composition-based stats. Identities = 199/720 (27%), Positives = 331/720 (45%), Gaps = 89/720 (12%) Query: 13 GDANVAPGSSPGGVWHQPQPPKDSAFHPMGWSLPKEKGLILCLWNKFCRWFHRRESWAQS 72 G+A V G Q PP +S F + + + F + + S A S Sbjct: 21 GNAEVNKGK-------QEPPPMESPFQ----REDRNSSPQIKVNLNFIKRPPKNTS-APS 68 Query: 73 RDEQNLLQQKRIWE--SPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAAL-- 128 + E + + R++ S + ++ L K+ + +G+ G+T L A L Sbjct: 69 QQEPDRFDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNL 128 Query: 129 YDNLEAA-MVLMEAAPE------LVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGA 181 D + A M L++ + LV T E Y+G +ALHIA+ +++ V+ L+ GA Sbjct: 129 QDGVNACIMPLLQIDKDSGNPKPLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGA 188 Query: 182 SVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEHG---ADIRAQDSLGNT 238 V RA G F Y+GE PLS AAC ++V L+E+ A + A DSLGNT Sbjct: 189 DVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNT 248 Query: 239 VLHILIL-----QPNKTFACQMYNLLLSYDGGD-HLKSLELVPNNQGLTPFKLAGVEGNI 292 VLH L++ N MY+ LL LE + N+QGLTP KLA EG I Sbjct: 249 VLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKI 308 Query: 293 VMFQHLMQK----------RKHIQWTYGPLTSTLYDLTEIDSSGDDQSLLELIVTTKKRE 342 +F+H++Q+ RK +W YGP+ +LYDL+ +DS + S+LE+I K Sbjct: 309 EIFRHILQREFSGPYQPLSRKFTEWCYGPVRVSLYDLSSVDS-WEKNSVLEIIAFHCKSP 367 Query: 343 AR-QILDQTPVKELVSLKWKRYGRPYFCVLGAIYVLYIICFTMCCVYRPLKPRITNRTNP 401 R +++ P+ +L+ KW R +F A Y++Y+ FT+ ++P Sbjct: 368 NRHRMVVLEPLNKLLQEKWDRLVSRFFF-NFACYLVYMFIFTVVAYHQPS---------- 416 Query: 402 RDNTLLQQKLLQEAYVTPKDDLRLVGELVSIVGAVIILLVEIPDIFRLGVTRFFGQTILG 461 L Q + + T + + L+G ++ ++G + +LL ++ +R + F + + Sbjct: 417 -----LDQPAIPSSKATFGESMLLLGHILILLGGIYLLLGQLWYFWRRRL--FIWISFMD 469 Query: 462 GPFHVIIVTYAFMVLVTMVMRLTNSDGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMI 521 F ++ + A + +++ V+R ++ + + +LVLGW N++Y+ RGFQ G +++MI Sbjct: 470 SYFEILFLLQALLTVLSQVLRFMETEWYLPLLVLSLVLGWLNLLYYTRGFQHTGIYSVMI 529 Query: 522 QKMIFGDLMRFCWLMAVVILGFASAFYIIFQ-------TEDPDELGHF----------YD 564 QK+I DL+RF + V + GFA A + + ED + Sbjct: 530 QKVILRDLLRFLLVYLVFLFGFAVALVSLSREARSPKAPEDNNSTVTEQPTVGQEEEPAP 589 Query: 565 YPMALFSTFELF-LTIIDGPANYDVDLPFMY--SITYAAFAIIATLLMLNLLIAMMGDTH 621 Y L ++ ELF TI G + L F + A+ ++ +L+LN+LIA+M +T Sbjct: 590 YRSILDASLELFKFTIGMGELAFQEQLRFRGVVLLLLLAYVLLTYVLLLNMLIALMSETV 649 Query: 622 WRVAHERDELWRAQVVATTVMLERKLPRCLWPRS------GICGREYGLGD-RWFLRVED 674 VA +W+ Q + + +E C + + R G D RW RVE+ Sbjct: 650 NHVADNSWSIWKLQKAISVLEMENGYWWCRRKKHREGRLLKVGTRGDGTPDERWCFRVEE 709 >6BO5-A nrPDB Length = 695 Score = 570 bits (1469), Expect = e-163, Method: Composition-based stats. Identities = 183/636 (28%), Positives = 302/636 (47%), Gaps = 75/636 (11%) Query: 95 ENNVQALIKLLKFEGCEVHQKGAMGETALHIAAL--YDNLEAA-MVLMEAAPE------L 145 ++ L K+ + +G+ G+T L A L D + A M L++ + L Sbjct: 53 TGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKPL 112 Query: 146 VFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEH 205 V T E Y+G +ALHIA+ +++ V+ L+ GA V RA G F Y+GE Sbjct: 113 VNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGEL 172 Query: 206 PLSFAACVGSEEIVRLLIEHG---ADIRAQDSLGNTVLHILIL-----QPNKTFACQMYN 257 PLS AAC ++V L+E+ A + A DSLGNTVLH L++ N MY+ Sbjct: 173 PLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYD 232 Query: 258 LLLSYDGGD-HLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQK----------RKHIQ 306 LL LE + N+QGLTP KLA EG I +F+H++Q+ RK + Sbjct: 233 GLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQREFSGPYQPLSRKFTE 292 Query: 307 WTYGPLTSTLYDLTEIDSSGDDQSLLELIVTTKKREAR-QILDQTPVKELVSLKWKRYGR 365 W YGP+ +LYDL+ +DS + S+LE+I K R +++ P+ +L+ KW R Sbjct: 293 WCYGPVRVSLYDLSSVDS-WEKNSVLEIIAFHCKSPNRHRMVVLEPLNKLLQEKWDRLVS 351 Query: 366 PYFCVLGAIYVLYIICFTMCCVYRPLKPRITNRTNPRDNTLLQQKLLQEAYVTPKDDLRL 425 +F A Y++Y+ FT+ ++P L Q + + T + + L Sbjct: 352 RFFF-NFACYLVYMFIFTVVAYHQPS---------------LDQPAIPSSKATFGESMLL 395 Query: 426 VGELVSIVGAVIILLVEIPDIFRLGVTRFFGQTILGGPFHVIIVTYAFMVLVTMVMRLTN 485 +G ++ ++G + +LL ++ +R + F + + F ++ + A + +++ V+R Sbjct: 396 LGHILILLGGIYLLLGQLWYFWRRRL--FIWISFMDSYFEILFLLQALLTVLSQVLRFME 453 Query: 486 SDGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFAS 545 ++ + + +LVLGW N++Y+ RGFQ G +++MIQK+I DL+RF + V + GFA Sbjct: 454 TEWYLPLLVLSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAV 513 Query: 546 AFYIIFQ-------TEDPDELGHF----------YDYPMALFSTFELF-LTIIDGPANYD 587 A + + ED + Y L ++ ELF TI G + Sbjct: 514 ALVSLSREARSPKAPEDNNSTVTEQPTVGQEEEPAPYRSILDASLELFKFTIGMGELAFQ 573 Query: 588 VDLPFMY--SITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQVVATTVMLER 645 L F + A+ ++ +L+LN+LIA+M +T VA +W+ Q + + +E Sbjct: 574 EQLRFRGVVLLLLLAYVLLTYVLLLNMLIALMSETVNHVADNSWSIWKLQKAISVLEMEN 633 Query: 646 KLPRCLWPRS------GICGREYGLGD-RWFLRVED 674 C + + R G D RW RVE+ Sbjct: 634 GYWWCRRKKHREGRLLKVGTRGDGTPDERWCFRVEE 669 >5AN8-A nrPDB Length = 613 Score = 570 bits (1468), Expect = e-162, Method: Composition-based stats. Identities = 182/619 (29%), Positives = 303/619 (48%), Gaps = 61/619 (9%) Query: 95 ENNVQALIKLLKFEGCEVHQKGAMGETALHIAAL--YDNLEAA-MVLMEAAPE------L 145 ++ L + K+ + +G+ G+T L A L D + A L+E + L Sbjct: 16 AGLLEYLRRTSKYLTDSEYTEGSTGKTCLMKAVLNLQDGVNACIQPLLEIDRDSGNPQPL 75 Query: 146 VFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEH 205 V T E Y G +ALHIA+ +++ V+ L+ GA+V A+A G F Y+GE Sbjct: 76 VNAQCTDEYYRGHSALHIAIEKRSLQCVKLLVENGANVHAKACGHFFQKNQDTCFYFGEL 135 Query: 206 PLSFAACVGSEEIVRLLIEHG---ADIRAQDSLGNTVLHILIL-----QPNKTFACQMYN 257 PLS AAC ++V L+E+ A ++AQDSLGNTVLH L++ N +MY+ Sbjct: 136 PLSLAACTKQWDVVNYLLENPHPAASLQAQDSLGNTVLHALVMIADNSPENSALVVRMYD 195 Query: 258 LLLSYDGGD-HLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQK----------RKHIQ 306 LL LE +PN +GLTP KLA EG I +F+H++Q+ RK + Sbjct: 196 GLLQAGARLCPNVQLEGIPNLEGLTPLKLAAKEGKIEIFKHILQREFSAPCQSLSRKFTE 255 Query: 307 WTYGPLTSTLYDLTEIDSSGDDQSLLELIVTTKKREAR-QILDQTPVKELVSLKWKRYGR 365 W YGP+ +LYDL +DS ++ S+LE+I + R +++ P+ +L+ KW R Sbjct: 256 WCYGPVRVSLYDLASVDS-WEENSVLEIIAFHSRSPHRHRMVVLEPLNKLLQAKWDRLI- 313 Query: 366 PYFCVLGAIYVLYIICFTMCCVYRPLKPRITNRTNPRDNTLLQQKLLQEAYVTPKDDLRL 425 P FC Y++Y++ FT ++P L+++ T + + L Sbjct: 314 PRFCFNFLCYLVYMLIFTAVAYHQP---------------ALEKQGFPPLKATAGNSMLL 358 Query: 426 VGELVSIVGAVIILLVEIPDIFRLGVTRFFGQTILGGPFHVIIVTYAFMVLVTMVMRLTN 485 +G ++ ++G V +LL ++ +R + F + + F ++ + A + +++ V+ Sbjct: 359 LGHILILLGGVYLLLGQLWYFWRRRL--FIWISFMDSYFEILFLLQALLTVLSQVLCFLA 416 Query: 486 SDGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFAS 545 + + + +LVLGW N++Y+ RGFQ G +++MIQK+I DL+RF + V + GFA Sbjct: 417 IEWYLPLLVSSLVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLVYLVFLFGFAV 476 Query: 546 AFYIIFQTEDPDELGHFYDYPMALFSTFELF-LTIIDGPANYDVDLPFMY--SITYAAFA 602 A + + DE Y L ++ ELF TI G + L F + A+ Sbjct: 477 ALVSLSREAQEDEA---PPYRSILDASLELFKFTIGMGELAFQEQLRFRGVVLLLLLAYV 533 Query: 603 IIATLLMLNLLIAMMGDTHWRVAHERDELWRAQVVATTVMLERKLPRCLWPRSG------ 656 ++ +L+LN+LIA+M +T VA + +W+ Q + + +E C + Sbjct: 534 LLTYVLLLNMLIALMSETVNSVATDSWSIWKLQKAISVLEMENGYWWCRRKKQRAGVMLT 593 Query: 657 ICGREYGLGD-RWFLRVED 674 + R G D RW RV + Sbjct: 594 VGTRPDGSPDERWCFRVGE 612 >6DVZ-A nrPDB Length = 791 Score = 564 bits (1454), Expect = e-161, Method: Composition-based stats. Identities = 189/666 (28%), Positives = 312/666 (46%), Gaps = 79/666 (11%) Query: 92 AAKENNVQALIKLLKFEGCEVH---------------QKGAMGETALHIAALY---DNLE 133 A E V+ L +LL+ G+T L A L + E Sbjct: 126 AVSEGCVEELRELLQDLQDLCRRRRGLDVPDFLMHKLTASDTGKTCLMKALLNINPNTKE 185 Query: 134 AAMVLMEAAPE------LVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARA 187 +L+ A E + T E YEGQTAL+IA+ + ++ L+A GA V+A A Sbjct: 186 IVRILLAFAEENDILDRFINAEYTEEAYEGQTALNIAIERRQGDITAVLIAAGADVNAHA 245 Query: 188 TGSVFHYR-PHNLIYYGEHPLSFAACVGSEEIVRLLIEH-GADIRAQDSLGNTVLHILI- 244 G F+ + H Y+GE PL+ AAC EIV+LL+E+ DI +QDS GN +LH L+ Sbjct: 246 KGVFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMENEQTDITSQDSRGNNILHALVT 305 Query: 245 ----LQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQ 300 + F +MY+++L G L E + NN GLTP +LA G + ++++ Sbjct: 306 VAEDFKTQNDFVKRMYDMILLRSGNWEL---ETMRNNDGLTPLQLAAKMGKAEILKYILS 362 Query: 301 K-----------RKHIQWTYGPLTSTLYDLTEIDSSGDDQSLLELIVTTKKREAR-QILD 348 + RK W YGP++S+LYDLT +D++ D S+LE+IV + R ++L Sbjct: 363 REIKEKPLRSLSRKFTDWAYGPVSSSLYDLTNVDTTTD-NSVLEIIVYNTNIDNRHEMLT 421 Query: 349 QTPVKELVSLKWKRYGRPYFCVLGAIYVLYIICFTMCCVYRPLKPRITNRTNPRDNTLLQ 408 P+ L+ KWK++ + F + Y Y I T+ YRP R++ L Sbjct: 422 LEPLHTLLHTKWKKFAKYMFFLSFCFYFFYNITLTLVSYYRP-----------REDEDLP 470 Query: 409 QKLLQEAYVTPKDDLRLVGELVSIVGAVIILLVEIPDIFRLGVTRFFGQTIL-GGPFHVI 467 L A L+L+G + ++ A I + E IF L + Q+IL FH + Sbjct: 471 HPL---ALTHKMSWLQLLGRMFVLIWATCISVKEGIAIFLLRPSDL--QSILSDAWFHFV 525 Query: 468 IVTYAFMVLVTMVMRLTNSDGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFG 527 A +V++++ + L + + A+ LGW N++ + RGFQ +G +++MIQK+I Sbjct: 526 FFVQAVLVILSVFLYLFAYKEYLACLVLAMALGWANMLAYTRGFQSMGMYSVMIQKVILH 585 Query: 528 DLMRFCWLMAVVILGFASAFYIIFQTE--DPDELGHFYDYPMALFSTFELFLTIIDGPAN 585 D+++F ++ + +LGF A + + D + + + A+ F+L + + D Sbjct: 586 DVLKFLFVYILFLLGFGVALASLIEKCSKDKKDCSSYGSFSDAVLELFKLTIGLGDLNIQ 645 Query: 586 YDVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQVVATTVMLER 645 + P ++ + I+ +L+LN+LIA+MG+T V+ E + +WR Q T + E+ Sbjct: 646 QNSTYPILFLFLLITYVILTFVLLLNMLIALMGETVENVSKESERIWRLQRARTILEFEK 705 Query: 646 KLPRCLWPRSGICG--REYGLGDRWFLRVEDRQ-----------DLNRQRIRRYAQAFQQ 692 LP L R + + R LR+ + + + + IRR A + Sbjct: 706 MLPEWLRSRFRMGELCKVADEDFRLCLRINEVKWTEWKTHVSFLNEDPGPIRRTADLNKI 765 Query: 693 QDDLYS 698 QD S Sbjct: 766 QDSSRS 771 Score = 48.9 bits (115), Expect = 7e-06, Method: Composition-based stats. Identities = 40/179 (22%), Positives = 69/179 (38%), Gaps = 26/179 (14%) Query: 57 NKFCRWFHRRESWAQSRDEQNLLQQKRIWESPLLLAAKENNVQALIKLLKFEGCEVHQKG 116 ++F + E++ + N+ ++R + +L A +V A K + F H+ Sbjct: 201 DRFINAEYTEEAYE-GQTALNIAIERRQGDITAVLIAAGADVNAHAKGVFFNPKYQHEGF 259 Query: 117 AMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVI-----NQNVN 171 GET L +AA + E +LME + TS+ G LH V + Sbjct: 260 YFGETPLALAACTNQPEIVQLLMENEQTDI----TSQDSRGNNILHALVTVAEDFKTQND 315 Query: 172 LVR-----ALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEH 225 V+ LL G + R ++ G PL AA +G EI++ ++ Sbjct: 316 FVKRMYDMILLRSG-------NWELETMRNND----GLTPLQLAAKMGKAEILKYILSR 363 >6MHW-A nrPDB Length = 826 Score = 548 bits (1413), Expect = e-156, Method: Composition-based stats. Identities = 178/615 (28%), Positives = 300/615 (48%), Gaps = 57/615 (9%) Query: 93 AKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALY---DNLEAAMVLMEAAPE----- 144 + + + + L + G+T L A L + E +L+ A E Sbjct: 147 CRRRHDEDVPDFLMHKL----TASDTGKTCLMKALLNINPNTKEIVRILLAFAEENDILG 202 Query: 145 -LVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYR-PHNLIYY 202 + T E YEGQTAL+IA+ + ++ L+A GA V+A A G+ F+ + H Y+ Sbjct: 203 RFINAEYTEEAYEGQTALNIAIERRQGDIAALLIAAGADVNAHAKGAFFNPKYQHEGFYF 262 Query: 203 GEHPLSFAACVGSEEIVRLLIEH-GADIRAQDSLGNTVLHILI-----LQPNKTFACQMY 256 GE PL+ AAC EIV+LL+EH DI ++DS GN +LH L+ + F +MY Sbjct: 263 GETPLALAACTNQPEIVQLLMEHEQTDITSRDSRGNNILHALVTVAEDFKTQNDFVKRMY 322 Query: 257 NLLLSYDGGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQK-----------RKHI 305 +++L G L E NN GLTP +LA G + ++++ + RK Sbjct: 323 DMILLRSGNWEL---ETTRNNDGLTPLQLAAKMGKAEILKYILSREIKEKRLRSLSRKFT 379 Query: 306 QWTYGPLTSTLYDLTEIDSSGDDQSLLELIVTTKKREAR-QILDQTPVKELVSLKWKRYG 364 W YGP++S+LYDLT +D++ D S+LE+ V + R ++L P+ L+ +KWK++ Sbjct: 380 DWAYGPVSSSLYDLTNVDTTTD-NSVLEITVYNTNIDNRHEMLTLEPLHTLLHMKWKKFA 438 Query: 365 RPYFCVLGAIYVLYIICFTMCCVYRPLKPRITNRTNPRDNTLLQQKLLQEAYVTPKDDLR 424 + F + Y Y I T+ YRP R+ + L A L+ Sbjct: 439 KHMFFLSFCFYFFYNITLTLVSYYRP-----------REEEAIPHPL---ALTHKMGWLQ 484 Query: 425 LVGELVSIVGAVIILLVEIPDIFRLGVTRFFGQTIL-GGPFHVIIVTYAFMVLVTMVMRL 483 L+G + ++ A+ I + E IF L + Q+IL FH + A +V++++ + L Sbjct: 485 LLGRMFVLIWAMCISVKEGIAIFLLRPSDL--QSILSDAWFHFVFFIQAVLVILSVFLYL 542 Query: 484 TNSDGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGF 543 + + A+ LGW N++Y+ RGFQ +G +++MIQK+I D+++F ++ V +LGF Sbjct: 543 FAYKEYLACLVLAMALGWANMLYYTRGFQSMGMYSVMIQKVILHDVLKFLFVYIVFLLGF 602 Query: 544 ASAFYIIFQ--TEDPDELGHFYDYPMALFSTFELFLTIIDGPANYDVDLPFMYSITYAAF 601 A + + +D + + + A+ F+L + + D + P ++ + Sbjct: 603 GVALASLIEKCPKDNKDCSSYGSFSDAVLELFKLTIGLGDLNIQQNSKYPILFLFLLITY 662 Query: 602 AIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQVVATTVMLERKLPRCLWPRSGICGRE 661 I+ +L+LN+LIA+MG+T V+ E + +WR Q T + E+ LP L R + Sbjct: 663 VILTFVLLLNMLIALMGETVENVSKESERIWRLQRARTILEFEKMLPEWLRSRFRMGELC 722 Query: 662 YGLGD--RWFLRVED 674 D R LR+ + Sbjct: 723 KVAEDDFRLCLRINE 737 >2RFA-A nrPDB Length = 232 Score = 296 bits (758), Expect = 2e-80, Method: Composition-based stats. Identities = 217/220 (98%), Positives = 219/220 (99%) Query: 84 IWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAP 143 IWESPLLLAAKEN+VQAL KLLKFEGCEVHQ+GAMGETALHIAALYDNLEAAMVLMEAAP Sbjct: 2 IWESPLLLAAKENDVQALSKLLKFEGCEVHQRGAMGETALHIAALYDNLEAAMVLMEAAP 61 Query: 144 ELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYG 203 ELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYG Sbjct: 62 ELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYG 121 Query: 204 EHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD 263 EHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD Sbjct: 122 EHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD 181 Query: 264 GGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKRK 303 GGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKRK Sbjct: 182 GGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKRK 221 >2ETB-A nrPDB Length = 256 Score = 213 bits (541), Expect = 3e-55, Method: Composition-based stats. Identities = 78/226 (34%), Positives = 113/226 (50%), Gaps = 18/226 (7%) Query: 95 ENNVQALIKLLKFEGCEVHQKGAMGETALHIAAL--YDNLEAA-MVLMEAAPE------L 145 ++ L K+ + +G+ G+T L A L D + A M L++ + L Sbjct: 19 TGLLEYLRWNSKYLTDSAYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKPL 78 Query: 146 VFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEH 205 V T E Y+G +ALHIA+ +++ V+ L+ GA V RA G F Y+GE Sbjct: 79 VNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGEL 138 Query: 206 PLSFAACVGSEEIVRLLIEH---GADIRAQDSLGNTVLHILIL-----QPNKTFACQMYN 257 PLS AAC ++V L+E+ A + A DSLGNTVLH L++ N MY+ Sbjct: 139 PLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYD 198 Query: 258 LLLSYDGGD-HLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKR 302 LL LE + N+QGLTP KLA EG I +F+H++Q+ Sbjct: 199 GLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQRE 244 >2F37-A nrPDB Length = 251 Score = 208 bits (530), Expect = 5e-54, Method: Composition-based stats. Identities = 74/226 (32%), Positives = 111/226 (49%), Gaps = 18/226 (7%) Query: 95 ENNVQALIKLLKFEGCEVHQKGAMGETALHIAAL--YDNLEAAMVLM-------EAAPEL 145 + L K K+ + +G+ G+T L A L D + A ++ + L Sbjct: 24 AGLPEYLSKTSKYLTDSEYTEGSTGKTCLMKAVLNLKDGVNACILPLLQIDRDSGNPQPL 83 Query: 146 VFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEH 205 V T + Y G +ALHIA+ +++ V+ L+ GA+V ARA G F Y+GE Sbjct: 84 VNAQCTDDYYRGHSALHIAIEKRSLQCVKLLVENGANVHARACGRFFQKGQGTCFYFGEL 143 Query: 206 PLSFAACVGSEEIVRLLIEH---GADIRAQDSLGNTVLHILILQPNKT-----FACQMYN 257 PLS AAC ++V L+E+ A ++A DS GNTVLH L++ + + MY+ Sbjct: 144 PLSLAACTKQWDVVSYLLENPHQPASLQATDSQGNTVLHALVMISDNSAENIALVTSMYD 203 Query: 258 LLLSYDGGD-HLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKR 302 LL LE + N Q LTP KLA EG I +F+H++Q+ Sbjct: 204 GLLQAGARLCPTVQLEDIRNLQDLTPLKLAAKEGKIEIFRHILQRE 249 >6AUN-A nrPDB Length = 752 Score = 187 bits (475), Expect = 1e-47, Method: Composition-based stats. Identities = 57/243 (23%), Positives = 99/243 (40%), Gaps = 38/243 (15%) Query: 85 WESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPE 144 +PL LA ++ + + L++L+++ ++ GETA H A DN + +L + A Sbjct: 152 GCTPLHLACRKGDSEILVELVQYCHAQMDVTDNKGETAFHYAVQGDNSQVLQLLGKNAS- 210 Query: 145 LVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGA----------------SVSARAT 188 + +G T LH+A +VR LL A S + Sbjct: 211 ---AGLNQVNKQGLTPLHLACQMGKQEMVRVLLLCNARCNVMGPSGFPIHTAMKFSQKGC 267 Query: 189 GSVFHYRPHNLIY-----YGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHIL 243 + + I+ YG PL +A + E+ R+L++ G D+ + + GNT LH+ Sbjct: 268 AEMIISMDSSQIHSKDPRYGASPLHWA---KNAEMARMLLKRGCDVDSTSAAGNTALHVA 324 Query: 244 ILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKRK 303 +++ F C M L + G P G TP LA + N+ M + L+ Sbjct: 325 VMR--NRFDCVMVLLTYGANAG--------TPGEHGNTPLHLAISKDNMEMIKALIVFGA 374 Query: 304 HIQ 306 + Sbjct: 375 EVD 377 Score = 95.6 bits (236), Expect = 7e-20, Method: Composition-based stats. Identities = 44/212 (20%), Positives = 77/212 (36%), Gaps = 31/212 (14%) Query: 80 QQKRIWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLM 139 Q + +PL LA + + ++++L + G G +H A + A +++ Sbjct: 215 QVNKQGLTPLHLACQMGKQE-MVRVLLLCNARCNVMGPSGF-PIHTAMKFSQKGCAEMII 272 Query: 140 EAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNL 199 + + G + LH A +N + R LL RG V + + Sbjct: 273 SMDSSQIHS---KDPRYGASPLHWA---KNAEMARMLLKRGCDVDSTSAA---------- 316 Query: 200 IYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLL 259 G L A + V +L+ +GA+ GNT LH+ I + N +M L Sbjct: 317 ---GNTALHVAVMRNRFDCVMVLLTYGANAGTPGEHGNTPLHLAISKDN----MEMIKAL 369 Query: 260 LSYDGGDHLKSLELVPNNQGLTPFKLAGVEGN 291 + + PN+ G TP +A Sbjct: 370 IVFGAEVD------TPNDFGETPAFMASKISK 395 >3W9G-A nrPDB Length = 260 Score = 186 bits (471), Expect = 4e-47, Method: Composition-based stats. Identities = 73/205 (35%), Positives = 103/205 (50%), Gaps = 19/205 (9%) Query: 117 AMGETALHIAALY---DNLEAAMVLME------AAPELVFEPMTSELYEGQTALHIAVIN 167 + G+T L A L + +L++ E + P Y GQTALHIA+ Sbjct: 44 STGKTCLPKALLNLSAGRNDTIPILLDIAEKTGNMREFINSPFRDVYYRGQTALHIAIER 103 Query: 168 QNVNLVRALLARGASVSARATGSVFHYRPH-NLIYYGEHPLSFAACVGSEEIVRLLIEHG 226 + + V L+ +GA V A+A G F + Y+GE PLS AAC IV L E+G Sbjct: 104 RCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHIVHYLTENG 163 Query: 227 ---ADIRAQDSLGNTVLHILI-----LQPNKTFACQMYNLLLSYDGGDHLKS-LELVPNN 277 AD+R QDS GNTVLH L+ + N F +MY+LLL + LE + NN Sbjct: 164 HKQADLRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLIKCAKLFPDTNLEALLNN 223 Query: 278 QGLTPFKLAGVEGNIVMFQHLMQKR 302 GL+P +A G I +FQH++++ Sbjct: 224 DGLSPLMMAAKTGKIGIFQHIIRRE 248 >4N5Q-A nrPDB Length = 257 Score = 185 bits (470), Expect = 5e-47, Method: Composition-based stats. Identities = 76/242 (31%), Positives = 114/242 (47%), Gaps = 34/242 (14%) Query: 92 AAKENNVQALIKLLKFEGCEVH---------------QKGAMGETALHIAALY---DNLE 133 A E V+ L +LL+ G+T L A L + E Sbjct: 10 AVSEGCVEELRELLQDLQDLCRRRRGLDVPDFLMHKLTASDTGKTCLMKALLNINPNTKE 69 Query: 134 AAMVLMEAAPE------LVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARA 187 +L+ A E + T E YEGQTAL+IA+ + ++ L+A GA V+A A Sbjct: 70 IVRILLAFAEENDILDRFINAEYTEEAYEGQTALNIAIERRQGDITAVLIAAGADVNAHA 129 Query: 188 TGSVFHYR-PHNLIYYGEHPLSFAACVGSEEIVRLLIEH-GADIRAQDSLGNTVLHILI- 244 G F+ + H Y+GE PL+ AAC EIV+LL+E+ DI +QDS GN +LH L+ Sbjct: 130 KGVFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMENEQTDITSQDSRGNNILHALVT 189 Query: 245 ----LQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQ 300 + F +MY+++L G L E + NN GLTP +LA G + ++++ Sbjct: 190 VAEDFKTQNDFVKRMYDMILLRSGNWEL---ETMRNNDGLTPLQLAAKMGKAEILKYILS 246 Query: 301 KR 302 + Sbjct: 247 RE 248 Score = 50.1 bits (118), Expect = 4e-06, Method: Composition-based stats. Identities = 40/179 (22%), Positives = 69/179 (38%), Gaps = 26/179 (14%) Query: 57 NKFCRWFHRRESWAQSRDEQNLLQQKRIWESPLLLAAKENNVQALIKLLKFEGCEVHQKG 116 ++F + E++ + N+ ++R + +L A +V A K + F H+ Sbjct: 85 DRFINAEYTEEAYE-GQTALNIAIERRQGDITAVLIAAGADVNAHAKGVFFNPKYQHEGF 143 Query: 117 AMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVI-----NQNVN 171 GET L +AA + E +LME + TS+ G LH V + Sbjct: 144 YFGETPLALAACTNQPEIVQLLMENEQTDI----TSQDSRGNNILHALVTVAEDFKTQND 199 Query: 172 LVR-----ALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEH 225 V+ LL G + R ++ G PL AA +G EI++ ++ Sbjct: 200 FVKRMYDMILLRSG-------NWELETMRNND----GLTPLQLAAKMGKAEILKYILSR 247 Score = 43.2 bits (100), Expect = 4e-04, Method: Composition-based stats. Identities = 36/163 (22%), Positives = 52/163 (31%), Gaps = 25/163 (15%) Query: 164 AVINQNVNLVRALLARGASVSARATG---SVFHYRPHNLIYYGEHPLSFAACV---GSEE 217 AV V +R LL + R G F G+ L A ++E Sbjct: 10 AVSEGCVEELRELLQDLQDLCRRRRGLDVPDFLMHKLTASDTGKTCLMKALLNINPNTKE 69 Query: 218 IVRLLIEHGADIRAQDSL-----------GNTVLHILILQPNKTFACQMYNLLLSYDGGD 266 IVR+L+ + D G T L+I I + + + D Sbjct: 70 IVRILLAFAEENDILDRFINAEYTEEAYEGQTALNIAIERRQGDITAVL--IAAGADVNA 127 Query: 267 HLKSLELVPNNQ------GLTPFKLAGVEGNIVMFQHLMQKRK 303 H K + P Q G TP LA + Q LM+ + Sbjct: 128 HAKGVFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMENEQ 170 >5AQ9-A nrPDB Length = 422 Score = 184 bits (467), Expect = 1e-46, Method: Composition-based stats. Identities = 52/187 (27%), Positives = 78/187 (41%), Gaps = 18/187 (9%) Query: 90 LLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEP 149 LL A +++L G +V+ G T LH+AA +LE VL++ ++ Sbjct: 18 LLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADV---- 73 Query: 150 MTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSF 209 + G T LH+A ++ +V LL GA V+A G PL Sbjct: 74 -DASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMD-------------SDGMTPLHL 119 Query: 210 AACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLK 269 AA G EIV +L++HGAD+ AQD G T + N + + G + Sbjct: 120 AAKWGYLEIVEVLLKHGADVNAQDKFGKTPFDLADDNGNDDVGTLLQVAAAADQLGARVG 179 Query: 270 SLELVPN 276 +EL N Sbjct: 180 YIELDLN 186 Score = 150 bits (378), Expect = 3e-36, Method: Composition-based stats. Identities = 48/186 (25%), Positives = 78/186 (41%), Gaps = 28/186 (15%) Query: 161 LHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVR 220 L A + VR L+A GA V+A G PL AA G EIV Sbjct: 18 LLEAARAGQDDEVRILMANGADVNAADNT-------------GTTPLHLAAYSGHLEIVE 64 Query: 221 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGL 280 +L++HGAD+ A D G T LH+ + + G + +++ G+ Sbjct: 65 VLLKHGADVDASDVFGYTPLHLAAYWGHLEIVEVLLK------NGADVNAMDS----DGM 114 Query: 281 TPFKLAGVEGNIVMFQHLMQKRKHI--QWTYGPLTSTLYDLTEIDSSGDDQSLLELIVTT 338 TP LA G + + + L++ + Q +G T +DL + + + D +LL++ Sbjct: 115 TPLHLAAKWGYLEIVEVLLKHGADVNAQDKFG---KTPFDLADDNGNDDVGTLLQVAAAA 171 Query: 339 KKREAR 344 + AR Sbjct: 172 DQLGAR 177 Score = 137 bits (344), Expect = 2e-32, Method: Composition-based stats. Identities = 40/145 (27%), Positives = 67/145 (46%), Gaps = 20/145 (13%) Query: 85 WESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPE 144 +PL LAA +++ + LLK G +V G T LH+AA + +LE VL++ + Sbjct: 47 GTTPLHLAAYSGHLEIVEVLLKH-GADVDASDVFGYTPLHLAAYWGHLEIVEVLLKNGAD 105 Query: 145 LVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGE 204 + + +G T LH+A + +V LL GA V+A+ +G+ Sbjct: 106 V-----NAMDSDGMTPLHLAAKWGYLEIVEVLLKHGADVNAQDK-------------FGK 147 Query: 205 HPLSFAACVGSEEIVRLL-IEHGAD 228 P A G++++ LL + AD Sbjct: 148 TPFDLADDNGNDDVGTLLQVAAAAD 172 >4DX2-A nrPDB Length = 259 Score = 183 bits (464), Expect = 2e-46, Method: Composition-based stats. Identities = 79/233 (33%), Positives = 111/233 (47%), Gaps = 23/233 (9%) Query: 93 AKENNVQALIKLLKFE----GCEVHQKGAMGETALHIAALY---DNLEAAMVLME----- 140 ++ L+ L E ++ + G+T L A L + VL++ Sbjct: 14 GSTADLDGLLPFLLTHKKRLTDEEFREPSTGKTCLPKALLNLSNGRNDTIPVLLDIAERT 73 Query: 141 -AAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPH-N 198 E + P Y GQTALHIA+ + + V L+A+GA V A+A G F + Sbjct: 74 GNMREFINSPFRDIYYRGQTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGG 133 Query: 199 LIYYGEHPLSFAACVGSEEIVRLLIEHG---ADIRAQDSLGNTVLHILI-----LQPNKT 250 Y+GE PLS AAC IV L E+ AD+R QDS GNTVLH L+ + N Sbjct: 134 YFYFGELPLSLAACTNQPHIVNYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTK 193 Query: 251 FACQMYNLLLSYDGGDHLKS-LELVPNNQGLTPFKLAGVEGNIVMFQHLMQKR 302 F +MY+LLL S LE V NN GL+P +A G I +FQH++++ Sbjct: 194 FVTKMYDLLLLKCARLFPDSNLEAVLNNDGLSPLMMAAKTGKIGIFQHIIRRE 246 >6MWQ-A nrPDB Length = 493 Score = 181 bits (460), Expect = 8e-46, Method: Composition-based stats. Identities = 54/172 (31%), Positives = 78/172 (45%), Gaps = 18/172 (10%) Query: 90 LLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEP 149 LL A +++L G +V+ G T LH+AA +LE VL++ ++ Sbjct: 9 LLEAARAGQDDEVRILMANGADVNALDRFGLTPLHLAAQRGHLEIVEVLLKCGADV---- 64 Query: 150 MTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSF 209 + GQT LH+A ++ +V LL GA V+A G+ PL Sbjct: 65 -NAADLWGQTPLHLAATAGHLEIVEVLLKYGADVNALD-------------LIGKTPLHL 110 Query: 210 AACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLS 261 A G EIV +L++HGAD+ AQD G T I I N+ A + L LS Sbjct: 111 TAIDGHLEIVEVLLKHGADVNAQDKFGKTAFDISIDNGNEDLAEILQKLNLS 162 Score = 124 bits (311), Expect = 1e-28, Method: Composition-based stats. Identities = 37/142 (26%), Positives = 69/142 (48%), Gaps = 19/142 (13%) Query: 83 RIWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAA 142 R +PL LAA+ +++ + LLK G +V+ G+T LH+AA +LE VL++ Sbjct: 36 RFGLTPLHLAAQRGHLEIVEVLLK-CGADVNAADLWGQTPLHLAATAGHLEIVEVLLKYG 94 Query: 143 PELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYY 202 ++ + G+T LH+ I+ ++ +V LL GA V+A+ + Sbjct: 95 ADV-----NALDLIGKTPLHLTAIDGHLEIVEVLLKHGADVNAQDK-------------F 136 Query: 203 GEHPLSFAACVGSEEIVRLLIE 224 G+ + G+E++ +L + Sbjct: 137 GKTAFDISIDNGNEDLAEILQK 158 Score = 123 bits (309), Expect = 3e-28, Method: Composition-based stats. Identities = 47/175 (26%), Positives = 81/175 (46%), Gaps = 28/175 (16%) Query: 161 LHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVR 220 L A + VR L+A GA V+A +G PL AA G EIV Sbjct: 9 LLEAARAGQDDEVRILMANGADVNALDR-------------FGLTPLHLAAQRGHLEIVE 55 Query: 221 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGL 280 +L++ GAD+ A D G T LH+ + ++ +LL Y G + +L+L+ G Sbjct: 56 VLLKCGADVNAADLWGQTPLHLAATAGH----LEIVEVLLKY--GADVNALDLI----GK 105 Query: 281 TPFKLAGVEGNIVMFQHLMQKRKHI--QWTYGPLTSTLYDLTEIDSSGDDQSLLE 333 TP L ++G++ + + L++ + Q +G T +D++ + + D +L+ Sbjct: 106 TPLHLTAIDGHLEIVEVLLKHGADVNAQDKFG---KTAFDISIDNGNEDLAEILQ 157 Score = 48.9 bits (115), Expect = 7e-06, Method: Composition-based stats. Identities = 28/151 (18%), Positives = 50/151 (33%), Gaps = 54/151 (35%) Query: 207 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGD 266 L AA G ++ VR+L+ +GAD+ A D G Sbjct: 9 LLEAARAGQDDEVRILMANGADVNALDRFG------------------------------ 38 Query: 267 HLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKRKHIQ----WTYGPLTSTLYDLTEI 322 LTP LA G++ + + L++ + W PL Sbjct: 39 -------------LTPLHLAAQRGHLEIVEVLLKCGADVNAADLWGQTPLHLAA------ 79 Query: 323 DSSGDDQSLLELIVTTKKREARQILDQTPVK 353 ++G + + L+ A ++ +TP+ Sbjct: 80 -TAGHLEIVEVLLKYGADVNALDLIGKTPLH 109 >5AQ7-A nrPDB Length = 418 Score = 181 bits (459), Expect = 1e-45, Method: Composition-based stats. Identities = 49/176 (27%), Positives = 75/176 (42%), Gaps = 18/176 (10%) Query: 90 LLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEP 149 LL A +++L G +V+ G T LH+AA +L VL++ ++ Sbjct: 18 LLEAARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADV---- 73 Query: 150 MTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSF 209 + G T LH+A ++ +V LL GA V+A G PL Sbjct: 74 -NANDERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATDV-------------IGTAPLHL 119 Query: 210 AACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGG 265 AA G +EIV +L++ GAD+ AQD G L + Q + A ++ L G Sbjct: 120 AAMWGYKEIVEVLLKAGADVDAQDKFGKRPLWLAADQGHAEIAAKLVAARLKARVG 175 Score = 122 bits (306), Expect = 6e-28, Method: Composition-based stats. Identities = 41/141 (29%), Positives = 60/141 (42%), Gaps = 19/141 (13%) Query: 85 WESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPE 144 +PL LAA E ++ + LLK G +V+ G T LH+AA +LE VL++ Sbjct: 47 GFTPLHLAAWEGHLGIVEVLLK-NGADVNANDERGHTPLHLAAYTGHLEIVEVLLKNGAG 105 Query: 145 LVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGE 204 + + G LH+A + +V LL GA V A+ +G+ Sbjct: 106 V-----NATDVIGTAPLHLAAMWGYKEIVEVLLKAGADVDAQDK-------------FGK 147 Query: 205 HPLSFAACVGSEEIVRLLIEH 225 PL AA G EI L+ Sbjct: 148 RPLWLAADQGHAEIAAKLVAA 168 Score = 108 bits (270), Expect = 8e-24, Method: Composition-based stats. Identities = 39/152 (25%), Positives = 61/152 (40%), Gaps = 25/152 (16%) Query: 161 LHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVR 220 L A + VR LLA GA V+ G PL AA G IV Sbjct: 18 LLEAARAGQDDEVRILLANGADVNTADET-------------GFTPLHLAAWEGHLGIVE 64 Query: 221 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGL 280 +L+++GAD+ A D G+T LH+ + ++ +LL G + + G Sbjct: 65 VLLKNGADVNANDERGHTPLHLAAYTGH----LEIVEVLLKNGAGVNATDVI------GT 114 Query: 281 TPFKLAGVEGNIVMFQHLMQKRKHI--QWTYG 310 P LA + G + + L++ + Q +G Sbjct: 115 APLHLAAMWGYKEIVEVLLKAGADVDAQDKFG 146 Score = 49.7 bits (117), Expect = 5e-06, Method: Composition-based stats. Identities = 18/55 (32%), Positives = 26/55 (47%), Gaps = 1/55 (1%) Query: 84 IWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVL 138 I +PL LAA + + LLK G +V + G+ L +AA + E A L Sbjct: 112 IGTAPLHLAAMWGYKEIVEVLLKA-GADVDAQDKFGKRPLWLAADQGHAEIAAKL 165 Score = 44.7 bits (104), Expect = 1e-04, Method: Composition-based stats. Identities = 22/115 (19%), Positives = 37/115 (32%), Gaps = 47/115 (40%) Query: 207 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGD 266 L AA G ++ VR+L+ +GAD+ D Sbjct: 18 LLEAARAGQDDEVRILLANGADVNTAD--------------------------------- 44 Query: 267 HLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKRKHI----QWTYGPLTSTLY 317 G TP LA EG++ + + L++ + + + PL Y Sbjct: 45 ----------ETGFTPLHLAAWEGHLGIVEVLLKNGADVNANDERGHTPLHLAAY 89 >5AQB-A nrPDB Length = 428 Score = 181 bits (459), Expect = 1e-45, Method: Composition-based stats. Identities = 52/184 (28%), Positives = 82/184 (44%), Gaps = 22/184 (11%) Query: 90 LLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEP 149 LL A ++L G +V+ +G T LH+AA + +LE L++ ++ Sbjct: 18 LLEAARAGQDDECRILMANGADVNALDEVGWTPLHLAA-WGHLEIVECLLKNGADV---- 72 Query: 150 MTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSF 209 + +G T LH+A + ++ +V LL GA V+A G PL Sbjct: 73 -NAADIDGYTPLHLAAFSGHLEIVEVLLKYGADVNADDQA-------------GFTPLHL 118 Query: 210 AACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQM---YNLLLSYDGGD 266 AA G EIV +L+++GAD+ AQD G T + I N+ A + L+ D D Sbjct: 119 AAIFGHLEIVEVLLKNGADVNAQDKFGKTPRDLAIDNGNEDIAEVLGKAATLVKVKDAAD 178 Query: 267 HLKS 270 L + Sbjct: 179 QLGA 182 Score = 115 bits (289), Expect = 6e-26, Method: Composition-based stats. Identities = 49/194 (25%), Positives = 78/194 (40%), Gaps = 38/194 (19%) Query: 161 LHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVR 220 L A + R L+A GA V+A G PL AA G EIV Sbjct: 18 LLEAARAGQDDECRILMANGADVNALDE-------------VGWTPLHLAA-WGHLEIVE 63 Query: 221 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGL 280 L+++GAD+ A D G T LH+ + ++ +LL Y + G Sbjct: 64 CLLKNGADVNAADIDGYTPLHLAAFSGH----LEIVEVLLKYGADVNADD------QAGF 113 Query: 281 TPFKLAGVEGNIVMFQHLMQKRKHI--QWTYGPLTSTLYDLTEIDSSGDD--------QS 330 TP LA + G++ + + L++ + Q +G T DL ID+ +D + Sbjct: 114 TPLHLAAIFGHLEIVEVLLKNGADVNAQDKFG---KTPRDLA-IDNGNEDIAEVLGKAAT 169 Query: 331 LLELIVTTKKREAR 344 L+++ + AR Sbjct: 170 LVKVKDAADQLGAR 183 Score = 98.6 bits (244), Expect = 9e-21, Method: Composition-based stats. Identities = 27/106 (25%), Positives = 51/106 (48%), Gaps = 6/106 (5%) Query: 85 WESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPE 144 +PL LAA +++ + LLK+ G +V+ G T LH+AA++ +LE VL++ + Sbjct: 79 GYTPLHLAAFSGHLEIVEVLLKY-GADVNADDQAGFTPLHLAAIFGHLEIVEVLLKNGAD 137 Query: 145 LVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGS 190 + ++ G+T +A+ N N ++ L V + Sbjct: 138 V-----NAQDKFGKTPRDLAIDNGNEDIAEVLGKAATLVKVKDAAD 178 >5AQA-A nrPDB Length = 418 Score = 179 bits (455), Expect = 3e-45, Method: Composition-based stats. Identities = 50/176 (28%), Positives = 76/176 (43%), Gaps = 18/176 (10%) Query: 90 LLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEP 149 LL A +++L G +V+ G T LH+AA +LE VL++ ++ Sbjct: 18 LLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADV---- 73 Query: 150 MTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSF 209 + G T LH+A ++ +V LL GA V+A G PL Sbjct: 74 -DASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMD-------------SDGMTPLHL 119 Query: 210 AACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGG 265 AA G +EIV +L++ GAD+ AQD G L + Q + A ++ L G Sbjct: 120 AAKWGYKEIVEVLLKAGADVDAQDKFGKRPLWLAADQGHAEIAAKLVAARLKARVG 175 Score = 135 bits (340), Expect = 6e-32, Method: Composition-based stats. Identities = 41/141 (29%), Positives = 62/141 (43%), Gaps = 19/141 (13%) Query: 85 WESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPE 144 +PL LAA +++ + LLK G +V G T LH+AA + +LE VL++ + Sbjct: 47 GTTPLHLAAYSGHLEIVEVLLKH-GADVDASDVFGYTPLHLAAYWGHLEIVEVLLKNGAD 105 Query: 145 LVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGE 204 + + +G T LH+A +V LL GA V A+ +G+ Sbjct: 106 V-----NAMDSDGMTPLHLAAKWGYKEIVEVLLKAGADVDAQDK-------------FGK 147 Query: 205 HPLSFAACVGSEEIVRLLIEH 225 PL AA G EI L+ Sbjct: 148 RPLWLAADQGHAEIAAKLVAA 168 Score = 131 bits (330), Expect = 9e-31, Method: Composition-based stats. Identities = 48/180 (26%), Positives = 69/180 (38%), Gaps = 28/180 (15%) Query: 123 LHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGAS 182 L AA + +LM ++ T G T LH+A + ++ +V LL GA Sbjct: 18 LLEAARAGQDDEVRILMANGADVNAADNT-----GTTPLHLAAYSGHLEIVEVLLKHGAD 72 Query: 183 VSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHI 242 V A +G PL AA G EIV +L+++GAD+ A DS G T LH+ Sbjct: 73 VDASDV-------------FGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHL 119 Query: 243 LILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKR 302 K + D D G P LA +G+ + L+ R Sbjct: 120 AAKWGYKEIVEVLLKAGADVDAQDKF----------GKRPLWLAADQGHAEIAAKLVAAR 169 Score = 122 bits (305), Expect = 7e-28, Method: Composition-based stats. Identities = 40/152 (26%), Positives = 61/152 (40%), Gaps = 25/152 (16%) Query: 161 LHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVR 220 L A + VR L+A GA V+A G PL AA G EIV Sbjct: 18 LLEAARAGQDDEVRILMANGADVNAADNT-------------GTTPLHLAAYSGHLEIVE 64 Query: 221 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGL 280 +L++HGAD+ A D G T LH+ + + G + +++ G+ Sbjct: 65 VLLKHGADVDASDVFGYTPLHLAAYWGHLEIVEVLLK------NGADVNAMDS----DGM 114 Query: 281 TPFKLAGVEGNIVMFQHLMQKRKHI--QWTYG 310 TP LA G + + L++ + Q +G Sbjct: 115 TPLHLAAKWGYKEIVEVLLKAGADVDAQDKFG 146 >6FES-A nrPDB Length = 367 Score = 177 bits (448), Expect = 2e-44, Method: Composition-based stats. Identities = 52/189 (27%), Positives = 80/189 (42%), Gaps = 19/189 (10%) Query: 90 LLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEP 149 LL A +++L G +V+ G T LH+AA +L VL++ ++ Sbjct: 10 LLEAARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADV---- 65 Query: 150 MTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSF 209 + G T LH+A ++ +V LL GA V+A G PL Sbjct: 66 -NANDERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATDV-------------IGTAPLHL 111 Query: 210 AACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLK 269 AA G EEIV +L+++GAD RAQD G T + ++ ++ + D LK Sbjct: 112 AAMWGHEEIVEVLLKNGADARAQDKFGKTPEDLARDNGYES-VARLARKEIIRAVVDELK 170 Query: 270 SLELVPNNQ 278 L N+ Sbjct: 171 ELIQNVNDD 179 Score = 118 bits (296), Expect = 9e-27, Method: Composition-based stats. Identities = 38/137 (27%), Positives = 58/137 (42%), Gaps = 19/137 (13%) Query: 85 WESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPE 144 +PL LAA E ++ + LLK G +V+ G T LH+AA +LE VL++ Sbjct: 39 GFTPLHLAAWEGHLGIVEVLLK-NGADVNANDERGHTPLHLAAYTGHLEIVEVLLKNGAG 97 Query: 145 LVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGE 204 + + G LH+A + + +V LL GA A+ +G+ Sbjct: 98 V-----NATDVIGTAPLHLAAMWGHEEIVEVLLKNGADARAQDK-------------FGK 139 Query: 205 HPLSFAACVGSEEIVRL 221 P A G E + RL Sbjct: 140 TPEDLARDNGYESVARL 156 Score = 113 bits (282), Expect = 4e-25, Method: Composition-based stats. Identities = 48/201 (23%), Positives = 78/201 (38%), Gaps = 40/201 (19%) Query: 161 LHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVR 220 L A + VR LLA GA V+ G PL AA G IV Sbjct: 10 LLEAARAGQDDEVRILLANGADVNTADET-------------GFTPLHLAAWEGHLGIVE 56 Query: 221 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGL 280 +L+++GAD+ A D G+T LH+ + ++ +LL G + + G Sbjct: 57 VLLKNGADVNANDERGHTPLHLAAYTGH----LEIVEVLLKNGAGVNATDVI------GT 106 Query: 281 TPFKLAGVEGNIVMFQHLMQKRKH--IQWTYGPLTSTLYDLTEIDSSGDDQSLLELIVTT 338 P LA + G+ + + L++ Q +G T DL D+ + + L Sbjct: 107 APLHLAAMWGHEEIVEVLLKNGADARAQDKFG---KTPEDLAR-DNGYESVARLA----- 157 Query: 339 KKREARQIL--DQTPVKELVS 357 ++I+ +KEL+ Sbjct: 158 ----RKEIIRAVVDELKELIQ 174 Score = 41.6 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 14/54 (25%), Positives = 23/54 (42%), Gaps = 1/54 (1%) Query: 84 IWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMV 137 I +PL LAA + + + LLK G + + G+T +A A + Sbjct: 104 IGTAPLHLAAMWGHEEIVEVLLK-NGADARAQDKFGKTPEDLARDNGYESVARL 156 >5MIO-C nrPDB Length = 573 Score = 176 bits (445), Expect = 5e-44, Method: Composition-based stats. Identities = 53/171 (30%), Positives = 82/171 (47%), Gaps = 18/171 (10%) Query: 90 LLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEP 149 LL A +++L G +V+ A G T LH+AA Y +LE VL++ ++ Sbjct: 414 LLEAARAGQDDEVRVLMANGADVNATDASGLTPLHLAATYGHLEIVEVLLKHGADV---- 469 Query: 150 MTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSF 209 ++ G T LH+A + ++ +V LL GA V+A T +G+ PL Sbjct: 470 -SASDLMGSTPLHLAALIGHLEIVEVLLKHGADVNAVDT-------------WGDTPLRL 515 Query: 210 AACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLL 260 AA +G +IV L++HGAD+ AQD G T I ++ A + L L Sbjct: 516 AAVMGHLKIVEALLKHGADVNAQDKFGKTAYDTSIDNGSEDLAEILQKLNL 566 Score = 129 bits (325), Expect = 4e-30, Method: Composition-based stats. Identities = 50/170 (29%), Positives = 75/170 (44%), Gaps = 29/170 (17%) Query: 161 LHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVR 220 L A + VR L+A GA V+A G PL AA G EIV Sbjct: 414 LLEAARAGQDDEVRVLMANGADVNATDAS-------------GLTPLHLAATYGHLEIVE 460 Query: 221 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGL 280 +L++HGAD+ A D +G+T LH+ L + + H + V + G Sbjct: 461 VLLKHGADVSASDLMGSTPLHLAALIGHLEIVEVLLK---------HGADVNAV-DTWGD 510 Query: 281 TPFKLAGVEGNIVMFQHLMQKRKHI--QWTYGPLTSTLYDLTEIDSSGDD 328 TP +LA V G++ + + L++ + Q +G T YD T ID+ +D Sbjct: 511 TPLRLAAVMGHLKIVEALLKHGADVNAQDKFG---KTAYD-TSIDNGSED 556 Score = 117 bits (294), Expect = 1e-26, Method: Composition-based stats. Identities = 39/140 (27%), Positives = 66/140 (47%), Gaps = 19/140 (13%) Query: 85 WESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPE 144 +PL LAA +++ + LLK G +V MG T LH+AAL +LE VL++ + Sbjct: 443 GLTPLHLAATYGHLEIVEVLLKH-GADVSASDLMGSTPLHLAALIGHLEIVEVLLKHGAD 501 Query: 145 LVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGE 204 + + G T L +A + ++ +V ALL GA V+A+ +G+ Sbjct: 502 V-----NAVDTWGDTPLRLAAVMGHLKIVEALLKHGADVNAQDK-------------FGK 543 Query: 205 HPLSFAACVGSEEIVRLLIE 224 + GSE++ +L + Sbjct: 544 TAYDTSIDNGSEDLAEILQK 563 Score = 51.3 bits (121), Expect = 2e-06, Method: Composition-based stats. Identities = 27/154 (17%), Positives = 50/154 (32%), Gaps = 62/154 (40%) Query: 207 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGD 266 L AA G ++ VR+L+ +GAD+ A D+ Sbjct: 414 LLEAARAGQDDEVRVLMANGADVNATDA-------------------------------- 441 Query: 267 HLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKRKHIQWTYGPLTSTLY--------- 317 GLTP LA G++ + + L++ + + ++ L+ Sbjct: 442 -----------SGLTPLHLAATYGHLEIVEVLLKHGADVSASDLMGSTPLHLAALIGHLE 490 Query: 318 ----------DLTEIDSSGDDQSLLELIVTTKKR 341 D+ +D+ GD L ++ K Sbjct: 491 IVEVLLKHGADVNAVDTWGDTPLRLAAVMGHLKI 524 >2NYJ-A nrPDB Length = 273 Score = 175 bits (443), Expect = 7e-44, Method: Composition-based stats. Identities = 74/207 (35%), Positives = 102/207 (49%), Gaps = 19/207 (9%) Query: 117 AMGETALHIAALY---DNLEAAMVLMEAA------PELVFEPMTSELYEGQTALHIAVIN 167 G+T L A L + +L++ A + V T Y+GQTALHIA+ Sbjct: 52 ETGKTCLLKAMLNLHNGQNDTIALLLDVARKTDSLKQFVNASYTDSYYKGQTALHIAIER 111 Query: 168 QNVNLVRALLARGASVSARATGSVFHYRPHN-LIYYGEHPLSFAACVGSEEIVRLLIEH- 225 +N+ LV L+ GA V A A G F Y+GE PLS AAC IV+ L+++ Sbjct: 112 RNMTLVTLLVENGADVQAAANGDFFKKTKGRPGFYFGELPLSLAACTNQLAIVKFLLQNS 171 Query: 226 --GADIRAQDSLGNTVLHILILQPNKT-----FACQMYNLLLSYDGGDH-LKSLELVPNN 277 ADI A+DS+GNTVLH L+ + T F MYN +L H LE + N Sbjct: 172 WQPADISARDSVGNTVLHALVEVADNTVDNTKFVTSMYNEILILGAKLHPTLKLEEITNR 231 Query: 278 QGLTPFKLAGVEGNIVMFQHLMQKRKH 304 +GLTP LA G I + +++Q+ H Sbjct: 232 KGLTPLALAASSGKIGVLAYILQREIH 258 Score = 40.1 bits (92), Expect = 0.004, Method: Composition-based stats. Identities = 23/109 (21%), Positives = 42/109 (38%), Gaps = 13/109 (11%) Query: 84 IWESPLLLAAKENNVQALIKLLKF--EGCEVHQKGAMGETALHIAA-----LYDNLEAAM 136 E PL LAA N + + LL+ + ++ + ++G T LH DN + Sbjct: 147 FGELPLSLAACTNQLAIVKFLLQNSWQPADISARDSVGNTVLHALVEVADNTVDNTKFVT 206 Query: 137 VLMEA----APELVFEPMTSE--LYEGQTALHIAVINQNVNLVRALLAR 179 + +L E +G T L +A + + ++ +L R Sbjct: 207 SMYNEILILGAKLHPTLKLEEITNRKGLTPLALAASSGKIGVLAYILQR 255 >6BY9-A nrPDB Length = 328 Score = 174 bits (440), Expect = 1e-43, Method: Composition-based stats. Identities = 56/206 (27%), Positives = 94/206 (45%), Gaps = 28/206 (13%) Query: 87 SPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 +PL+ AA+ N+++A+ L+K G V K A G T LH+AA + E L+ V Sbjct: 137 TPLMEAAENNHLEAVKYLIKA-GALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDV 195 Query: 147 FEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHP 206 + G T + A ++V+LV+ LL++G+ ++ R N+ Sbjct: 196 ----NCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDN-------EENIC------ 238 Query: 207 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGD 266 L +AA G +I +L+ D+ A + G++ LHI + + C + L LS D Sbjct: 239 LHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIAARE--NRYDCVV--LFLSRDSDV 294 Query: 267 HLKSLELVPNNQGLTPFKLAGVEGNI 292 LK N +G TP + A + + Sbjct: 295 TLK------NKEGETPLQCASLNSQV 314 Score = 104 bits (260), Expect = 1e-22, Method: Composition-based stats. Identities = 38/175 (21%), Positives = 66/175 (37%), Gaps = 18/175 (10%) Query: 85 WESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPE 144 + L LAAK+ + + + LL +V+ + G T + A Y +++ +L+ + Sbjct: 168 GSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSD 227 Query: 145 LVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGE 204 + E LH A + V++ LLA + A +G+ Sbjct: 228 INIR-----DNEENICLHWAAFSGCVDIAEILLAAKCDLHAVN-------------IHGD 269 Query: 205 HPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLL 259 PL AA + V L + +D+ ++ G T L L A QM L Sbjct: 270 SPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCASLNSQVWSALQMSKAL 324 Score = 63.6 bits (153), Expect = 3e-10, Method: Composition-based stats. Identities = 27/143 (18%), Positives = 46/143 (32%), Gaps = 21/143 (14%) Query: 161 LHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVR 220 L+ + + V +L G + F N PL AA G +I Sbjct: 71 LYFSARQGELQKVLLMLVDGIDPN-------FKMEHQNK----RSPLHAAAEAGHVDICH 119 Query: 221 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGL 280 +L++ GA+I T L + + D D +G Sbjct: 120 MLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDA----------EGS 169 Query: 281 TPFKLAGVEGNIVMFQHLMQKRK 303 T LA +G+ + Q+L+ + Sbjct: 170 TCLHLAAKKGHYEVVQYLLSNGQ 192 >3B7B-A nrPDB Length = 237 Score = 174 bits (440), Expect = 1e-43, Method: Composition-based stats. Identities = 56/206 (27%), Positives = 94/206 (45%), Gaps = 28/206 (13%) Query: 87 SPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 +PL+ AA+ N+++A+ L+K G V K A G T LH+AA + E L+ V Sbjct: 46 TPLMEAAENNHLEAVKYLIKA-GALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDV 104 Query: 147 FEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHP 206 + G T + A ++V+LV+ LL++G+ ++ R N+ Sbjct: 105 ----NCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDN-------EENIC------ 147 Query: 207 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGD 266 L +AA G +I +L+ D+ A + G++ LHI + + C + L LS D Sbjct: 148 LHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIAARE--NRYDCVV--LFLSRDSDV 203 Query: 267 HLKSLELVPNNQGLTPFKLAGVEGNI 292 LK N +G TP + A + + Sbjct: 204 TLK------NKEGETPLQCASLNSQV 223 Score = 104 bits (260), Expect = 1e-22, Method: Composition-based stats. Identities = 38/175 (21%), Positives = 66/175 (37%), Gaps = 18/175 (10%) Query: 85 WESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPE 144 + L LAAK+ + + + LL +V+ + G T + A Y +++ +L+ + Sbjct: 77 GSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSD 136 Query: 145 LVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGE 204 + E LH A + V++ LLA + A +G+ Sbjct: 137 INIR-----DNEENICLHWAAFSGCVDIAEILLAAKCDLHAVN-------------IHGD 178 Query: 205 HPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLL 259 PL AA + V L + +D+ ++ G T L L A QM L Sbjct: 179 SPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCASLNSQVWSALQMSKAL 233 Score = 61.3 bits (147), Expect = 2e-09, Method: Composition-based stats. Identities = 21/99 (21%), Positives = 35/99 (35%), Gaps = 10/99 (10%) Query: 205 HPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDG 264 PL AA G +I +L++ GA+I T L + + D Sbjct: 13 SPLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDP 72 Query: 265 GDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKRK 303 D +G T LA +G+ + Q+L+ + Sbjct: 73 KDA----------EGSTCLHLAAKKGHYEVVQYLLSNGQ 101 >5H76-A nrPDB Length = 201 Score = 174 bits (440), Expect = 1e-43, Method: Composition-based stats. Identities = 55/188 (29%), Positives = 81/188 (43%), Gaps = 24/188 (12%) Query: 90 LLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEP 149 LL A +++L G +V+ G T LH+AA +LE VL++ ++ Sbjct: 10 LLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADV---- 65 Query: 150 MTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSF 209 + G T LH+A ++ +V LL GA V+A G PL Sbjct: 66 -DASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMD-------------SDGMTPLHL 111 Query: 210 AACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLK 269 AA G EIV +L++HGA + AQD G T I I N+ A +L++ HL Sbjct: 112 AAKWGYLEIVEVLLKHGA-VNAQDKFGKTAFDISIDNGNEDLAQ-----ILAFYEILHLP 165 Query: 270 SLELVPNN 277 +L N Sbjct: 166 NLNEEQRN 173 Score = 134 bits (337), Expect = 1e-31, Method: Composition-based stats. Identities = 49/195 (25%), Positives = 81/195 (41%), Gaps = 36/195 (18%) Query: 161 LHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVR 220 L A + VR L+A GA V+A G PL AA G EIV Sbjct: 10 LLEAARAGQDDEVRILMANGADVNAADNT-------------GTTPLHLAAYSGHLEIVE 56 Query: 221 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGL 280 +L++HGAD+ A D G T LH+ + + G + +++ G+ Sbjct: 57 VLLKHGADVDASDVFGYTPLHLAAYWGHLEIVEVLLK------NGADVNAMDS----DGM 106 Query: 281 TPFKLAGVEGNIVMFQHLMQKRK-HIQWTYGPLTSTLYDLTEIDSSGDDQSLLELIVTTK 339 TP LA G + + + L++ + Q +G T +D++ ID+ +D L +++ Sbjct: 107 TPLHLAAKWGYLEIVEVLLKHGAVNAQDKFG---KTAFDIS-IDNGNED--LAQILAFY- 159 Query: 340 KREARQILDQTPVKE 354 +IL + E Sbjct: 160 -----EILHLPNLNE 169 Score = 125 bits (313), Expect = 9e-29, Method: Composition-based stats. Identities = 36/138 (26%), Positives = 64/138 (46%), Gaps = 20/138 (14%) Query: 85 WESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPE 144 +PL LAA +++ + LLK G +V G T LH+AA + +LE VL++ + Sbjct: 39 GTTPLHLAAYSGHLEIVEVLLKH-GADVDASDVFGYTPLHLAAYWGHLEIVEVLLKNGAD 97 Query: 145 LVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGE 204 + + +G T LH+A + +V LL GA V+A+ +G+ Sbjct: 98 V-----NAMDSDGMTPLHLAAKWGYLEIVEVLLKHGA-VNAQDK-------------FGK 138 Query: 205 HPLSFAACVGSEEIVRLL 222 + G+E++ ++L Sbjct: 139 TAFDISIDNGNEDLAQIL 156 >4OAU-C nrPDB Length = 699 Score = 169 bits (427), Expect = 5e-42, Method: Composition-based stats. Identities = 61/264 (23%), Positives = 111/264 (42%), Gaps = 34/264 (12%) Query: 81 QKRIWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLME 140 +K+ +P +LAA +V+ L+KL +G +V++ G TA AA+Y ++A L + Sbjct: 68 RKKNGATPFILAAIAGSVK-LLKLFLSKGADVNECDFYGFTAFMEAAVYGKVKALKFLYK 126 Query: 141 AAPELVFEPMTSELYE-----GQTALHIAVINQNVNLVRALL-ARGASVSARATGSVFHY 194 + T E E G TAL A +V +++ LL GA V+A + Sbjct: 127 RGANVNLRRKTKEDQERLRKGGATALMDAAEKGHVEVLKILLDEMGADVNACD-----NM 181 Query: 195 RPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQ 254 + LI H L + E I LL++HGAD+ + G T L + + + + + Sbjct: 182 GRNALI----HALLSSDDSDVEAITHLLLDHGADVNVRGERGKTPLILAVEKKHLGLVQR 237 Query: 255 MYNLLLSYDGGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKRKHIQWTYGPLTS 314 + +H++ + ++ G T LA + + L ++ G Sbjct: 238 LLE-------QEHIEIND--TDSDGKTALLLAVELKLKKIAELLCKRGASTD--CG---- 282 Query: 315 TLYDLTEIDSSGDDQSLLELIVTT 338 DL D SL++++++ Sbjct: 283 ---DLVMTARRNYDHSLVKVLLSH 303 Score = 137 bits (345), Expect = 2e-32, Method: Composition-based stats. Identities = 62/288 (21%), Positives = 111/288 (38%), Gaps = 56/288 (19%) Query: 86 ESPLLLAAKENNVQALIKLLKFEGCEVH-QKGAMGETALHIAALYDNLEAAMVLMEAAPE 144 ++ LL+ A +N L++ L G V+ Q+ G T LH A + +L+ + Sbjct: 5 DNHLLIKAVQNEDVDLVQQLLEGGANVNFQEEEGGWTPLHNAVQMSREDIVELLLRHGAD 64 Query: 145 LVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSV------------- 191 V G T +A I +V L++ L++GA V+ Sbjct: 65 PVLRKKN-----GATPFILAAIAGSVKLLKLFLSKGADVNECDFYGFTAFMEAAVYGKVK 119 Query: 192 -----------------FHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEH-GADIRAQD 233 L G L AA G E++++L++ GAD+ A D Sbjct: 120 ALKFLYKRGANVNLRRKTKEDQERLRKGGATALMDAAEKGHVEVLKILLDEMGADVNACD 179 Query: 234 SLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGLTPFKLAGVEGNIV 293 ++G L +L + + + +LLL + + V +G TP LA + ++ Sbjct: 180 NMGRNALIHALLSSDDSDVEAITHLLLDHGADVN------VRGERGKTPLILAVEKKHLG 233 Query: 294 MFQHLMQKRKHIQWTYGPLTSTLYDLTEIDSSGDDQSLLELIVTTKKR 341 + Q L++ ++HI+ + + DS G LL + + KK Sbjct: 234 LVQRLLE-QEHIE------------INDTDSDGKTALLLAVELKLKKI 268 Score = 55.1 bits (131), Expect = 1e-07, Method: Composition-based stats. Identities = 23/102 (22%), Positives = 48/102 (47%), Gaps = 10/102 (9%) Query: 81 QKRIWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLME 140 + ++PL+LA ++ ++ + +LL+ E E++ + G+TAL +A + A +L + Sbjct: 215 RGERGKTPLILAVEKKHLGLVQRLLEQEHIEINDTDSDGKTALLLAVELKLKKIAELLCK 274 Query: 141 AAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGAS 182 + + A N + +LV+ LL+ GA Sbjct: 275 RGASTDCGDL----------VMTARRNYDHSLVKVLLSHGAK 306 >4O1O-A nrPDB Length = 717 Score = 164 bits (416), Expect = 1e-40, Method: Composition-based stats. Identities = 57/231 (24%), Positives = 93/231 (40%), Gaps = 25/231 (10%) Query: 81 QKRIWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLME 140 +KR +P ++A NV+ L++LL +V++ G TA AA+Y +EA L E Sbjct: 71 RKRNGATPFIIAGITGNVR-LLQLLLPNVEDVNECDVNGFTAFMEAAVYGRVEALRFLYE 129 Query: 141 AAPELVFEPMTSELYE-----GQTALHIAVINQNVNLVRALL-ARGASVSARATGSVFHY 194 ++ T + E G TAL A +V +V LL A A V AR + Sbjct: 130 NGADVNMHRKTKQDQERIRKGGATALMDAAEKGHVGVVTILLHAMKAEVDARD-----NM 184 Query: 195 RPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQ 254 + L+Y +P A + I RLL++HGAD+ + T L + + + N Sbjct: 185 GRNALVYALLNPDDGKA----KAITRLLLDHGADVNVRGEGSKTPLILAVERKNLDLVQ- 239 Query: 255 MYNLLLSYDGGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKRKHI 305 +L + + +G T LA + + L + Sbjct: 240 ----MLLEQEQIEVNDTD----REGKTALLLAVELRLEEIAKLLCHRGAST 282 Score = 64.7 bits (156), Expect = 1e-10, Method: Composition-based stats. Identities = 37/145 (25%), Positives = 57/145 (39%), Gaps = 22/145 (15%) Query: 161 LHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVR 220 L AV ++ VR LL RGA + + +G PL A + SE++V Sbjct: 12 LTQAVQEADIEQVRQLLERGADANFQEEE------------WGWSPLHSAVQMDSEDLVA 59 Query: 221 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGL 280 LL++HGAD + G T I + N ++ LLL + + G Sbjct: 60 LLLKHGADPCLRKRNGATPFIIAGITGN----VRLLQLLLPNVEDVNECDVN------GF 109 Query: 281 TPFKLAGVEGNIVMFQHLMQKRKHI 305 T F A V G + + L + + Sbjct: 110 TAFMEAAVYGRVEALRFLYENGADV 134 Score = 63.6 bits (153), Expect = 3e-10, Method: Composition-based stats. Identities = 28/98 (28%), Positives = 46/98 (46%), Gaps = 4/98 (4%) Query: 90 LLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEP 149 LL + +A+ +LL G +V+ +G +T L +A NL+ +L+E V Sbjct: 193 LLNPDDGKAKAITRLLLDHGADVNVRGEGSKTPLILAVERKNLDLVQMLLEQEQIEV--- 249 Query: 150 MTSELYEGQTALHIAVINQNVNLVRALLARGASVSARA 187 EG+TAL +AV + + + L RGAS + Sbjct: 250 -NDTDREGKTALLLAVELRLEEIAKLLCHRGASTNCGD 286 >6G1K-A nrPDB Length = 921 Score = 164 bits (415), Expect = 1e-40, Method: Composition-based stats. Identities = 102/658 (15%), Positives = 222/658 (33%), Gaps = 107/658 (16%) Query: 63 FHRRESWAQSRDEQNLL-----QQKRIWESPLLLAAKENNVQALIKLL----KFEGCEVH 113 + RR + RD L + E L A ++ + ++ L + ++ Sbjct: 5 YFRRTDNSSYRDRIPLRIVRAESELSTQEKSYLSAVEKGDYASVKLALEEAEIYFKININ 64 Query: 114 QKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLV 173 +G TAL IA +NLE +L+ +Y G LH A+ + V V Sbjct: 65 CIDPLGRTALLIAIENENLEIIELLLSFN-----------VYVGDALLH-AIRKEVVGAV 112 Query: 174 RALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADI-RAQ 232 LL + + + + P+ AA + EI+++L++ G + + Sbjct: 113 ELLLNHKKPSGEKQVPPILLDKQFSDFTPDITPIILAAHTNNYEIIKMLVQKGVSVPQPH 172 Query: 233 DSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGLTPFKLAGVEGNI 292 + N V + + + L Y + L + LT F+L+ + Sbjct: 173 EVRCNCV--ECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQEL 230 Query: 293 VMFQHLMQKR--------KHIQWTYGPLTSTLYDLTEIDSSGDDQSLLELIVTTK----- 339 ++ + KH T + +L I + DD +LL+ + Sbjct: 231 SKVENEFKAEYEELSHQCKHFAKDLLDQTRSSRELELILNFRDDMNLLQDEANNELARLK 290 Query: 340 ---KREARQILDQTPVKELVSLKWKR------------------YGRPYFCVLGAIYVLY 378 K ++ + Q ++L++ +W + F +L Y++ Sbjct: 291 LAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAGKLITCVFIGLMFPLLSLCYLVA 350 Query: 379 ------IIC----FTMCCVYRPLKPRITNRTNPRDNTLLQQKLLQEAYVTPKDDLRLVGE 428 + C + + + Q T + + Sbjct: 351 PKSRYGLFIRKPFIKFICHTASYLTFLFLLLLASQHIVSNNPDRQGPKPTTVEWM----- 405 Query: 429 LVSIVGAVIILLVEIPDIFRLGVTRFF--GQTILGGPFHVIIVTYAFMVLVTMVMRL--- 483 + + + EI ++ G + ++ + + + + +V V Sbjct: 406 --ILPWVLGFIWTEIKQMWDGGFQDYIHDWWNLMDFVMNSLYLATISLKIVAYVKYSGCK 463 Query: 484 --TNSDGEVVPMSFALVLGWCNVMYFAR------GFQMLGPFTIMIQKMIFGDLMRFCWL 535 + + V N+ R LGP I + +M+ D+++F ++ Sbjct: 464 PRDTWEMWHPTLVAEAVFAIANIFSSLRLISLFTANSHLGPLQISLGRMLL-DILKFLFI 522 Query: 536 MAVVILGFASAF---YIIFQTED------------PDELGHFYDYPMALF-STFELF-LT 578 +V+L FA+ Y ++ + + ++ +LF S F L L Sbjct: 523 YCLVLLAFANGLNQLYFYYENSEGMTCKGIRCERQNNAFSTLFETLQSLFWSIFGLISLY 582 Query: 579 IIDGPANYDVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQV 636 + + A++ F+ + + + +I+ +++LN+LIAMM +++ +A D W+ Sbjct: 583 VTNVKADHKFT-EFVGATMFGTYNVISLVVLLNMLIAMMNNSYQHIADHADIEWKFAR 639 >5GP7-A nrPDB Length = 169 Score = 152 bits (385), Expect = 4e-37, Method: Composition-based stats. Identities = 42/159 (26%), Positives = 66/159 (41%), Gaps = 18/159 (11%) Query: 85 WESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPE 144 ++ LL AAK+ + + KL E T LH+AA Y+NLE A L+E + Sbjct: 9 GDAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGAD 68 Query: 145 LVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGE 204 + ++ G LH A +V++ L+ V+A + Sbjct: 69 V-----NAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDK-------------WAF 110 Query: 205 HPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHIL 243 PL AA G ++ LL+ HGAD ++ G T L + Sbjct: 111 TPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLA 149 Score = 80.1 bits (196), Expect = 4e-15, Method: Composition-based stats. Identities = 38/172 (22%), Positives = 54/172 (31%), Gaps = 23/172 (13%) Query: 152 SELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAA 211 S+L G AL A + V+ L +++ R T PL AA Sbjct: 4 SDLLRGDAALLDAAKKGCLARVQKLCTP-ENINCRDTQGRNS-----------TPLHLAA 51 Query: 212 CVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSL 271 + E+ L+EHGAD+ AQD G LH + A + + D Sbjct: 52 GYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATD----- 106 Query: 272 ELVPNNQGLTPFKLAGVEGNIVMFQHLMQKRKHIQWTYGPLTSTLYDLTEID 323 TP A +G + L+ T DL D Sbjct: 107 -----KWAFTPLHEAAQKGRTQLCALLLAHGADPTMK-NQEGQTPLDLATAD 152 Score = 69.4 bits (168), Expect = 6e-12, Method: Composition-based stats. Identities = 27/97 (27%), Positives = 40/97 (41%), Gaps = 10/97 (10%) Query: 81 QKRIWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLME 140 Q + PL AA +V L+K+ C V+ T LH AA + +L+ Sbjct: 72 QDKGGLIPLHNAASYGHVDIAALLIKYNTC-VNATDKWAFTPLHEAAQKGRTQLCALLLA 130 Query: 141 AAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALL 177 + T + EGQT L +A + +RALL Sbjct: 131 HGAD-----PTMKNQEGQTPLDLATA----DDIRALL 158 >5Z96-A nrPDB Length = 755 Score = 148 bits (373), Expect = 9e-36, Method: Composition-based stats. Identities = 125/792 (15%), Positives = 269/792 (33%), Gaps = 135/792 (17%) Query: 59 FCRWFHRRESWAQSRDEQNL-LQQKRIWESP----LLLAAKENNVQALIKLL----KFEG 109 +++++R A RD L + + SP L A ++ + ++ K L + Sbjct: 1 MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFK 60 Query: 110 CEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQN 169 ++ +G TAL IA EL+ ++ +Y G LH A+ + Sbjct: 61 ININCIDPLGRTALLIAIEN-----------ENLELIELLLSFNVYVGDALLH-AIRKEV 108 Query: 170 VNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADI 229 V V LL + + + + P+ AA + EI++LL++ G + Sbjct: 109 VGAVELLLNHKKPSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSV 168 Query: 230 -----------RAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQ 278 S L + N A +L+ L + +L Q Sbjct: 169 PRPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQ 228 Query: 279 GLTPFKLAGVEGNIVMFQHLMQKRKHIQWTYGPLTSTLYDLTEIDSSGDDQSLLELIVTT 338 L+ + + + Q K + T + +L I + DD SL+E Sbjct: 229 ELSKVENEFKSEYEELSRQCKQFAKDLLDQ----TRSSRELEIILNYRDDNSLIEEQSGN 284 Query: 339 K--------KREARQILDQTPVKELVSLKW-KRY-----------------GRPYFCVLG 372 K ++ + Q ++L++ +W + F V Sbjct: 285 DLARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFS 344 Query: 373 AIYVLY---------------IICFTMCCVYRPLKPRITNRTNPRDNTLLQQKLLQEAYV 417 Y++ IC T Y + + D + L ++ Sbjct: 345 VCYLIAPKSPLGLFIRKPFIKFICHT--ASYLTFLFLLLLASQHIDRSDLNRQGPPP--- 399 Query: 418 TPKDDLRLVGELVSIVGAVIILLVEIPDIFRLGVTRFF--GQTILGGPFHVIIVTYAFMV 475 T + + + + + EI ++ G+ + ++ + + + + Sbjct: 400 TIVEWM-------ILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLK 452 Query: 476 LVTMVMRLT-----NSDGEVVPMSFALVLGWCNVMYFAR------GFQMLGPFTIMIQKM 524 +V V + D + + N+ R LGP I + +M Sbjct: 453 IVAFVKYSALNPRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRM 512 Query: 525 IFGDLMRFCWLMAVVILGFASAF---YIIFQT------------EDPDELGHFYDYPMAL 569 + D+++F ++ +V+L FA+ Y ++ + + ++ +L Sbjct: 513 LL-DILKFLFIYCLVLLAFANGLNQLYFYYEETKGLSCKGIRCEKQNNAFSTLFETLQSL 571 Query: 570 F-STFELF-LTIIDGPANYDVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHE 627 F S F L L + + A ++ F+ + + + +I+ +++LN+LIAMM +++ +A Sbjct: 572 FWSIFGLINLYVTNVKAQHEFT-EFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADH 630 Query: 628 RDELWRAQVVATTVMLERKLPRCLWPRSGICGREYGL----GDRWFLRVEDRQDLNRQRI 683 D W+ KL + G + + W+L L ++++ Sbjct: 631 ADIEWKFART--------KLWMSYFEEGGTLPTPFNVIPSPKSLWYLVKWIWTHLCKKKM 682 Query: 684 RRYAQAFQQQDDLYSEDLEKDSGEKLEMARPFGAYLSFPTPSVSRSTSRSSTNWDRLRQ- 742 RR ++F +++L + + M Y++ + N L+Q Sbjct: 683 RRKPESFGTIGRRAADNLRRHHQYQEVMRNLVKRYVAAMIREAKTEEGLTEENVKELKQD 742 Query: 743 -GALRKDLQGII 753 + R ++ G++ Sbjct: 743 ISSFRFEVLGLL 754 >4NIK-A nrPDB Length = 230 Score = 138 bits (348), Expect = 7e-33, Method: Composition-based stats. Identities = 44/159 (27%), Positives = 66/159 (41%), Gaps = 19/159 (11%) Query: 85 WESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPE 144 SPL +AA ++K L +G +V+ G T LH AA + E A++L+E Sbjct: 77 GWSPLHIAASAGR-DEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGA- 134 Query: 145 LVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGE 204 P + YE TA+H A N+ ++ LL AS + + T G Sbjct: 135 ---NPDAKDHYEA-TAMHRAAAKGNLKMIHILLYYKASTNIQDT-------------EGN 177 Query: 205 HPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHIL 243 PL A E +LL+ GA I ++ T L + Sbjct: 178 TPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVA 216 Score = 126 bits (316), Expect = 4e-29, Method: Composition-based stats. Identities = 52/213 (24%), Positives = 85/213 (39%), Gaps = 28/213 (13%) Query: 93 AKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTS 152 A ++ L + + + + TALH A + E L++ P+ Sbjct: 18 AYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLG-----VPVND 72 Query: 153 ELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAAC 212 + G + LHIA +V+ALL +GA V+A G PL +AA Sbjct: 73 KDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQN-------------GCTPLHYAAS 119 Query: 213 VGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLE 272 EI +L+E GA+ A+D T +H + N +M ++LL Y +++ E Sbjct: 120 KNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGN----LKMIHILLYYKASTNIQDTE 175 Query: 273 LVPNNQGLTPFKLAGVEGNIVMFQHLMQKRKHI 305 G TP LA E + + L+ + I Sbjct: 176 ------GNTPLHLACDEERVEEAKLLVSQGASI 202 Score = 117 bits (292), Expect = 2e-26, Method: Composition-based stats. Identities = 47/209 (22%), Positives = 83/209 (39%), Gaps = 31/209 (14%) Query: 87 SPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 + L A + + + LL+ G V+ K G + LHIAA E L+ ++ Sbjct: 46 TALHWACSAGHTEIVEFLLQ-LGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQV- 103 Query: 147 FEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHP 206 + G T LH A + LL GA+ A+ +Y Sbjct: 104 ----NAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKD-------------HYEATA 146 Query: 207 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGD 266 + AA G+ +++ +L+ + A QD+ GNT LH+ + A LL+S Sbjct: 147 MHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEA----KLLVSQGASI 202 Query: 267 HLKSLELVPNNQGLTPFKLAGVEGNIVMF 295 +++ N + TP ++A +G + + Sbjct: 203 YIE------NKEEKTPLQVA--KGGLGLI 223 Score = 95.2 bits (235), Expect = 9e-20, Method: Composition-based stats. Identities = 52/229 (22%), Positives = 85/229 (37%), Gaps = 34/229 (14%) Query: 127 ALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSAR 186 A LE + + T + TALH A + +V LL G V+ + Sbjct: 18 AYSGKLE--ELKESILADKSLATRTDQDSR--TALHWACSAGHTEIVEFLLQLGVPVNDK 73 Query: 187 ATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQ 246 G PL AA G +EIV+ L+ GA + A + G T LH + Sbjct: 74 DDA-------------GWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASK 120 Query: 247 PNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKRK--H 304 A + + D DH ++ T A +GN+ M L+ + + Sbjct: 121 NRHEIAVMLLEGGANPDAKDHYEA----------TAMHRAAAKGNLKMIHILLYYKASTN 170 Query: 305 IQWTYGPLTSTLYDLTEIDSSGDDQSLLELIVTTKKREARQILDQTPVK 353 IQ T G +T L + ++ LL + E ++ ++TP++ Sbjct: 171 IQDTEG---NTPLHLACDEERVEEAKLLVSQGASIYIENKE--EKTPLQ 214 Score = 35.5 bits (80), Expect = 0.087, Method: Composition-based stats. Identities = 14/46 (30%), Positives = 22/46 (47%), Gaps = 1/46 (2%) Query: 81 QKRIWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIA 126 Q +PL LA E V+ KLL +G ++ + +T L +A Sbjct: 172 QDTEGNTPLHLACDEERVEE-AKLLVSQGASIYIENKEEKTPLQVA 216 >4Z68-A nrPDB Length = 155 Score = 137 bits (344), Expect = 2e-32, Method: Composition-based stats. Identities = 40/158 (25%), Positives = 65/158 (41%), Gaps = 18/158 (11%) Query: 86 ESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPEL 145 + LL AAK +V+ + KL + T LH AA Y+ + L++ ++ Sbjct: 4 DRQLLEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADV 63 Query: 146 VFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEH 205 ++ G LH A + + L+ GA V+ + Sbjct: 64 H-----AKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVAD-------------LWKFT 105 Query: 206 PLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHIL 243 PL AA G EI +LL++HGAD ++ GNT L ++ Sbjct: 106 PLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLV 143 Score = 75.5 bits (184), Expect = 8e-14, Method: Composition-based stats. Identities = 42/172 (24%), Positives = 61/172 (35%), Gaps = 24/172 (13%) Query: 161 LHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVR 220 L A +V V+ L SV+ R PL FAA +V Sbjct: 7 LLEAAKAGDVETVKKLCTVQ-SVNCRDIEGRQS-----------TPLHFAAGYNRVSVVE 54 Query: 221 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGL 280 L++HGAD+ A+D G LH + A LL+ + ++ L Sbjct: 55 YLLQHGADVHAKDKGGLVPLHNACSYGHYEVA----ELLVKHGAVVNVADL------WKF 104 Query: 281 TPFKLAGVEGNIVMFQHLMQKRKHIQWTYGPLTSTLYDLTEIDSSGDDQSLL 332 TP A +G + + L+Q +T DL + D D Q LL Sbjct: 105 TPLHEAAAKGKYEICKLLLQHGADPTKK-NRDGNTPLDLVK-DGDTDIQDLL 154 >5HKP-A nrPDB Length = 351 Score = 136 bits (343), Expect = 3e-32, Method: Composition-based stats. Identities = 59/344 (17%), Positives = 115/344 (33%), Gaps = 37/344 (10%) Query: 89 LLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFE 148 LL AA+ N + L+ LL H T LH+AA Y+ + +L++ ++ Sbjct: 28 LLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVH-- 85 Query: 149 PMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLS 208 ++ G LH A + + LL GA V+A + PL Sbjct: 86 ---AKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMD-------------LWQFTPLH 129 Query: 209 FAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNL--LLSYDGGD 266 AA E+ LL+ HGAD + G + + + + + LL Sbjct: 130 EAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREA 189 Query: 267 HLKSLELVPNNQ---------GLTPFKLAGVE---GNIVMFQHLMQKRKHIQWTYGPLTS 314 L ++ + T A + + L++K ++ + Sbjct: 190 DLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVAELLLRKGANVNEKNKDFMT 249 Query: 315 TLYDLTEIDSSGDDQSLLELIVTT-KKREARQILDQTPVKELVSLKWKRYGRPYFCVLGA 373 L+ + + ++E++ K A L QT + + R Sbjct: 250 PLH----VAAERAHNDVMEVLHKHGAKMNALDSLGQTALHRAALAGHLQTCRLLLSYGSD 305 Query: 374 IYVLYIICFTMCCVYRPLKPRITNRTNPRDNTLLQQKLLQEAYV 417 ++ + FT + +I + + P + + +LL+ + Sbjct: 306 PSIISLQGFTAAQMGNEAVQQILSESTPMRTSDVDYRLLEASKA 349 Score = 112 bits (280), Expect = 6e-25, Method: Composition-based stats. Identities = 50/263 (19%), Positives = 87/263 (33%), Gaps = 60/263 (22%) Query: 86 ESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPEL 145 +PL LAA N V+ +++LL G +VH K G LH A Y + E +L++ + Sbjct: 59 STPLHLAAGYNRVR-IVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACV 117 Query: 146 VFEPMTSELYEGQTALHIAVINQNVNLVRALLARGAS---VSARATGSVF----HYRPHN 198 + T LH A V + LL+ GA V+ +V Sbjct: 118 -----NAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRER 172 Query: 199 LIYY----------------------------------GEHPLSFAACVGSE---EIVRL 221 L Y E L A ++ L Sbjct: 173 LTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVAEL 232 Query: 222 LIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGLT 281 L+ GA++ ++ T LH+ + + + + G + +L+ + G T Sbjct: 233 LLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVL------HKHGAKMNALDSL----GQT 282 Query: 282 PFKLAGVEGNIVMFQHLMQKRKH 304 A + G++ + L+ Sbjct: 283 ALHRAALAGHLQTCRLLLSYGSD 305 Score = 99.8 bits (247), Expect = 4e-21, Method: Composition-based stats. Identities = 58/272 (21%), Positives = 93/272 (34%), Gaps = 81/272 (29%) Query: 81 QKRIWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLME 140 + + PL A + + + +LL G V+ T LH AA + +E +L+ Sbjct: 87 KDKGGLVPLHNACSYGHYE-VTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLS 145 Query: 141 AAPE---LVFEPMTSEL--------------YEGQ------------------------- 158 + + ++ ++G Sbjct: 146 HGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINF 205 Query: 159 -------TALHIAVINQN---VNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLS 208 TALH AV + + + LL +GA+V+ + + PL Sbjct: 206 KQPQSHETALHCAVASLHPKRKQVAELLLRKGANVNEKNKDFM-------------TPLH 252 Query: 209 FAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHL 268 AA +++ +L +HGA + A DSLG T LH L + Q LLLSY + Sbjct: 253 VAAERAHNDVMEVLHKHGAKMNALDSLGQTALHRAALAGH----LQTCRLLLSYGSDPSI 308 Query: 269 KSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQ 300 SL QG T A GN Q ++ Sbjct: 309 ISL------QGFT----AAQMGN-EAVQQILS 329 Score = 62.4 bits (150), Expect = 6e-10, Method: Composition-based stats. Identities = 23/104 (22%), Positives = 51/104 (49%), Gaps = 10/104 (9%) Query: 73 RDEQNLLQQKRIWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNL 132 R N+ ++ + + +PL +AA+ + ++++L G +++ ++G+TALH AAL +L Sbjct: 235 RKGANVNEKNKDFMTPLHVAAERAH-NDVMEVLHKHGAKMNALDSLGQTALHRAALAGHL 293 Query: 133 EAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRAL 176 + +L+ + + +G T A N + + L Sbjct: 294 QTCRLLLSYGSDPSIISL-----QGFT----AAQMGNEAVQQIL 328 >5JHQ-A nrPDB Length = 482 Score = 136 bits (342), Expect = 3e-32, Method: Composition-based stats. Identities = 52/281 (18%), Positives = 95/281 (33%), Gaps = 37/281 (13%) Query: 89 LLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFE 148 LL AA+ N + L+ LL H T LH+AA Y+ + +L++ ++ Sbjct: 172 LLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVH-- 229 Query: 149 PMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLS 208 ++ G LH A + + LL GA V+A + PL Sbjct: 230 ---AKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMD-------------LWQFTPLH 273 Query: 209 FAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNL--LLSYDGGD 266 AA E+ LL+ HGAD + G + + + + + LL Sbjct: 274 EAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREA 333 Query: 267 HLKSLELVPNNQ---------GLTPFKLAGVE---GNIVMFQHLMQKRKHIQWTYGPLTS 314 L ++ + T A + + L++K ++ + Sbjct: 334 DLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMT 393 Query: 315 TLYDLTEIDSSGDDQSLLELIVTT-KKREARQILDQTPVKE 354 L+ + + ++E++ K A L QT + Sbjct: 394 PLH----VAAERAHNDVMEVLHKHGAKMNALDTLGQTALHR 430 Score = 131 bits (330), Expect = 8e-31, Method: Composition-based stats. Identities = 50/234 (21%), Positives = 88/234 (37%), Gaps = 35/234 (14%) Query: 89 LLLAAKENNVQALIKLLKFEGCEVHQKGAMG--ETALHIAALYDNLEAAMVLMEAAPELV 146 LL A + +V + +L+ + V+ K G + LH AA + + L++ + Sbjct: 19 LLEACRNGDVSRVKRLV--DAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVH 76 Query: 147 FEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHP 206 G LH A + +V LL +GA +AR + P Sbjct: 77 AR-----DDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDN-------------WNYTP 118 Query: 207 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMY---NLLLSYD 263 L AA G ++ +L++HGAD +++ G + L + K Y LL + Sbjct: 119 LHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLA-DPSAKAVLTGEYKKDELLEAAR 177 Query: 264 GGDHLKSLELVP---------NNQGLTPFKLAGVEGNIVMFQHLMQKRKHIQWT 308 G+ K + L+ + + TP LA + + Q L+Q + Sbjct: 178 SGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAK 231 Score = 112 bits (280), Expect = 6e-25, Method: Composition-based stats. Identities = 50/263 (19%), Positives = 87/263 (33%), Gaps = 60/263 (22%) Query: 86 ESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPEL 145 +PL LAA N V+ +++LL G +VH K G LH A Y + E +L++ + Sbjct: 203 STPLHLAAGYNRVR-IVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACV 261 Query: 146 VFEPMTSELYEGQTALHIAVINQNVNLVRALLARGAS---VSARATGSVF----HYRPHN 198 + T LH A V + LL+ GA V+ +V Sbjct: 262 -----NAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRER 316 Query: 199 LIYY----------------------------------GEHPLSFAACVGSE---EIVRL 221 L Y E L A ++ L Sbjct: 317 LTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVTEL 376 Query: 222 LIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGLT 281 L+ GA++ ++ T LH+ + + + + G + +L+ + G T Sbjct: 377 LLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVL------HKHGAKMNALDTL----GQT 426 Query: 282 PFKLAGVEGNIVMFQHLMQKRKH 304 A + G++ + L+ Sbjct: 427 ALHRAALAGHLQTCRLLLSYGSD 449 Score = 99.0 bits (245), Expect = 7e-21, Method: Composition-based stats. Identities = 57/272 (20%), Positives = 93/272 (34%), Gaps = 81/272 (29%) Query: 81 QKRIWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLME 140 + + PL A + + + +LL G V+ T LH AA + +E +L+ Sbjct: 231 KDKGGLVPLHNACSYGHYE-VTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLS 289 Query: 141 AAPE---LVFEPMTSEL--------------YEGQ------------------------- 158 + + ++ ++G Sbjct: 290 HGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINF 349 Query: 159 -------TALHIAVINQN---VNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLS 208 TALH AV + + + LL +GA+V+ + + PL Sbjct: 350 KQPQSHETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFM-------------TPLH 396 Query: 209 FAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHL 268 AA +++ +L +HGA + A D+LG T LH L + Q LLLSY + Sbjct: 397 VAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGH----LQTCRLLLSYGSDPSI 452 Query: 269 KSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQ 300 SL QG T A GN Q ++ Sbjct: 453 ISL------QGFT----AAQMGN-EAVQQILS 473 Score = 77.4 bits (189), Expect = 2e-14, Method: Composition-based stats. Identities = 43/199 (21%), Positives = 73/199 (36%), Gaps = 31/199 (15%) Query: 161 LHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVR 220 L A N +V+ V+ L+ A+V+A+ PL FAA G +++V Sbjct: 19 LLEACRNGDVSRVKRLVDA-ANVNAKDMAGRKS-----------SPLHFAAGFGRKDVVE 66 Query: 221 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGL 280 L++ GA++ A+D G LH + + +LLL + +N Sbjct: 67 HLLQMGANVHARDDGGLIPLHNACSFGHAE----VVSLLLCQGADPN------ARDNWNY 116 Query: 281 TPFKLAGVEGNIVMFQHLMQKRKHIQWTYGPLTSTLYDLTE------IDSSGDDQSLLEL 334 TP A ++G I + L+Q + DL + + LLE Sbjct: 117 TPLHEAAIKGKIDVCIVLLQHGADPNIR-NTDGKSALDLADPSAKAVLTGEYKKDELLE- 174 Query: 335 IVTTKKREARQILDQTPVK 353 E + + TP+ Sbjct: 175 -AARSGNEEKLMALLTPLN 192 Score = 62.0 bits (149), Expect = 1e-09, Method: Composition-based stats. Identities = 23/104 (22%), Positives = 50/104 (48%), Gaps = 10/104 (9%) Query: 73 RDEQNLLQQKRIWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNL 132 R N+ ++ + + +PL +AA+ + ++++L G +++ +G+TALH AAL +L Sbjct: 379 RKGANVNEKNKDFMTPLHVAAERAH-NDVMEVLHKHGAKMNALDTLGQTALHRAALAGHL 437 Query: 133 EAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRAL 176 + +L+ + + +G T A N + + L Sbjct: 438 QTCRLLLSYGSDPSIISL-----QGFT----AAQMGNEAVQQIL 472 >2DWZ-A nrPDB Length = 231 Score = 134 bits (337), Expect = 1e-31, Method: Composition-based stats. Identities = 43/159 (27%), Positives = 64/159 (40%), Gaps = 19/159 (11%) Query: 85 WESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPE 144 SPL +AA ++K L +G V+ G T LH AA + E A++L+E Sbjct: 73 GWSPLHIAASAGR-DEIVKALLVKGAHVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGA- 130 Query: 145 LVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGE 204 P + Y+ TA+H A N+ +V LL AS + + T G Sbjct: 131 ---NPDAKDHYDA-TAMHRAAAKGNLKMVHILLFYKASTNIQDT-------------EGN 173 Query: 205 HPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHIL 243 PL A E + L+ GA I ++ T L + Sbjct: 174 TPLHLACDEERVEEAKFLVTQGASIYIENKEEKTPLQVA 212 Score = 125 bits (313), Expect = 1e-28, Method: Composition-based stats. Identities = 52/213 (24%), Positives = 84/213 (39%), Gaps = 28/213 (13%) Query: 93 AKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTS 152 A + L + + + + TALH A + E L++ P+ Sbjct: 14 AYSGKLDELKERILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLG-----VPVND 68 Query: 153 ELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAAC 212 + G + LHIA +V+ALL +GA V+A G PL +AA Sbjct: 69 KDDAGWSPLHIAASAGRDEIVKALLVKGAHVNAVNQN-------------GCTPLHYAAS 115 Query: 213 VGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLE 272 EI +L+E GA+ A+D T +H + N +M ++LL Y +++ E Sbjct: 116 KNRHEIAVMLLEGGANPDAKDHYDATAMHRAAAKGN----LKMVHILLFYKASTNIQDTE 171 Query: 273 LVPNNQGLTPFKLAGVEGNIVMFQHLMQKRKHI 305 G TP LA E + + L+ + I Sbjct: 172 ------GNTPLHLACDEERVEEAKFLVTQGASI 198 Score = 93.6 bits (231), Expect = 3e-19, Method: Composition-based stats. Identities = 48/205 (23%), Positives = 79/205 (38%), Gaps = 30/205 (14%) Query: 151 TSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFA 210 T + +TALH A + +V LL G V+ + G PL A Sbjct: 34 TRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDA-------------GWSPLHIA 80 Query: 211 ACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKS 270 A G +EIV+ L+ GA + A + G T LH + A + + D DH + Sbjct: 81 ASAGRDEIVKALLVKGAHVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYDA 140 Query: 271 LELVPNNQGLTPFKLAGVEGNIVMFQHLM--QKRKHIQWTYGPLTSTLYDLTEIDSSGDD 328 T A +GN+ M L+ + +IQ T G +T L + ++ Sbjct: 141 ----------TAMHRAAAKGNLKMVHILLFYKASTNIQDTEG---NTPLHLACDEERVEE 187 Query: 329 QSLLELIVTTKKREARQILDQTPVK 353 L + E ++ ++TP++ Sbjct: 188 AKFLVTQGASIYIENKE--EKTPLQ 210 Score = 50.9 bits (120), Expect = 2e-06, Method: Composition-based stats. Identities = 22/100 (22%), Positives = 42/100 (42%), Gaps = 8/100 (8%) Query: 81 QKRIWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLME 140 + + + AA + N++ + LL ++ + + G T LH+A + +E A L+ Sbjct: 135 KDHYDATAMHRAAAKGNLKMVHILLFYK-ASTNIQDTEGNTPLHLACDEERVEEAKFLVT 193 Query: 141 AAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARG 180 + E E +T L +A + L+ LA G Sbjct: 194 QGASIYI-----ENKEEKTPLQVA--KGGLGLILKRLAEG 226 >5CBO-A nrPDB Length = 176 Score = 125 bits (313), Expect = 8e-29, Method: Composition-based stats. Identities = 32/138 (23%), Positives = 59/138 (42%), Gaps = 18/138 (13%) Query: 90 LLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEP 149 LL A +++L G +V+ G T LH+AA + + E VL++ ++ Sbjct: 7 LLEAAHAGQDDEVRILMANGADVNAMDNFGVTPLHLAAYWGHFEIVEVLLKYGADV---- 62 Query: 150 MTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSF 209 + G T LH+A + +V LL GA V+A+ +G+ Sbjct: 63 -NASDATGDTPLHLAAKWGYLGIVEVLLKYGADVNAQDK-------------FGKTAFDI 108 Query: 210 AACVGSEEIVRLLIEHGA 227 + G+E++ +L ++ A Sbjct: 109 SIDNGNEDLAEILCKNKA 126 Score = 122 bits (307), Expect = 5e-28, Method: Composition-based stats. Identities = 38/133 (28%), Positives = 55/133 (41%), Gaps = 18/133 (13%) Query: 123 LHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGAS 182 L AA + +LM ++ + G T LH+A + +V LL GA Sbjct: 7 LLEAAHAGQDDEVRILMANGADV-----NAMDNFGVTPLHLAAYWGHFEIVEVLLKYGAD 61 Query: 183 VSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHI 242 V+A G+ PL AA G IV +L+++GAD+ AQD G T I Sbjct: 62 VNASDAT-------------GDTPLHLAAKWGYLGIVEVLLKYGADVNAQDKFGKTAFDI 108 Query: 243 LILQPNKTFACQM 255 I N+ A + Sbjct: 109 SIDNGNEDLAEIL 121 Score = 93.2 bits (230), Expect = 3e-19, Method: Composition-based stats. Identities = 29/98 (29%), Positives = 49/98 (50%), Gaps = 6/98 (6%) Query: 84 IWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAP 143 +PL LAA + + + LLK+ G +V+ A G+T LH+AA + L VL++ Sbjct: 35 FGVTPLHLAAYWGHFEIVEVLLKY-GADVNASDATGDTPLHLAAKWGYLGIVEVLLKYGA 93 Query: 144 ELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGA 181 ++ ++ G+TA I++ N N +L L A Sbjct: 94 DV-----NAQDKFGKTAFDISIDNGNEDLAEILCKNKA 126 Score = 90.5 bits (223), Expect = 2e-18, Method: Composition-based stats. Identities = 37/139 (26%), Positives = 63/139 (45%), Gaps = 18/139 (12%) Query: 207 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGD 266 L AA G ++ VR+L+ +GAD+ A D+ G T LH+ + LL Y Sbjct: 7 LLEAAHAGQDDEVRILMANGADVNAMDNFGVTPLHLAAYWGHFEIVEV----LLKYGADV 62 Query: 267 HLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKRKHI--QWTYGPLTSTLYDLTEIDS 324 + G TP LA G + + + L++ + Q +G T +D++ ID+ Sbjct: 63 NASDAT------GDTPLHLAAKWGYLGIVEVLLKYGADVNAQDKFG---KTAFDIS-IDN 112 Query: 325 SGDDQSLLELIVTTKKREA 343 +D L E++ K ++A Sbjct: 113 GNED--LAEILCKNKAQQA 129 Score = 52.8 bits (125), Expect = 6e-07, Method: Composition-based stats. Identities = 18/60 (30%), Positives = 32/60 (53%), Gaps = 1/60 (1%) Query: 85 WESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPE 144 ++PL LAAK + + LLK+ G +V+ + G+TA I+ N + A +L + + Sbjct: 69 GDTPLHLAAKWGYLGIVEVLLKY-GADVNAQDKFGKTAFDISIDNGNEDLAEILCKNKAQ 127 >5ET1-A nrPDB Length = 353 Score = 117 bits (294), Expect = 2e-26, Method: Composition-based stats. Identities = 48/244 (19%), Positives = 79/244 (32%), Gaps = 33/244 (13%) Query: 79 LQQKRIWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAM-V 137 + + R +P AA + L LL GC V +K G T LH+AA + + + + Sbjct: 65 VSRARNGATPAHDAAATGYLSCLQWLLTQGGCRVQEKDNSGATVLHLAARFGHPDVVKWL 124 Query: 138 LMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALL-ARGASVSARATGSVFHYRP 196 L + T G +H A ++ ++ L+ V+A+ Sbjct: 125 LYQGGANSAITTDT-----GALPIHYAAAKGDLPSLKLLVGHYPEGVNAQTNN------- 172 Query: 197 HNLIYYGEHPLSFAACVGSEEIVRLLIEH-GADIRAQDSLGNTVLHILILQPNKTFACQM 255 G PL A G E+ + L++ AD + G T LH + Sbjct: 173 ------GATPLYLACQEGHLEVTKYLVQECSADPHLRAQDGMTPLHAAAQMGHNP----- 221 Query: 256 YNLLLSYDGGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKRKHIQ---WTYGPL 312 + L + + G T A G+ + L+ I W PL Sbjct: 222 VLVWLVSFADVSFSEQD----HDGATAMHFAASRGHTKVLSWLLLHGAEISQDLWGGTPL 277 Query: 313 TSTL 316 Sbjct: 278 HDAA 281 Score = 101 bits (251), Expect = 2e-21, Method: Composition-based stats. Identities = 49/233 (21%), Positives = 86/233 (36%), Gaps = 32/233 (13%) Query: 69 WAQSRDEQNLLQQKRIWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAAL 128 W ++ + ++ + L LAA+ + + LL G G +H AA Sbjct: 89 WLLTQGGCRVQEKDNSGATVLHLAARFGHPDVVKWLLYQGGANSAITTDTGALPIHYAAA 148 Query: 129 YDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALL-ARGASVSARA 187 +L + +L+ PE V + G T L++A ++ + + L+ A RA Sbjct: 149 KGDLPSLKLLVGHYPEGVNAQTNN----GATPLYLACQEGHLEVTKYLVQECSADPHLRA 204 Query: 188 TGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADI--RAQDSLGNTVLHILIL 245 G PL AA +G ++ L+ AD+ QD G T +H Sbjct: 205 QD-------------GMTPLHAAAQMGHNPVLVWLVSF-ADVSFSEQDHDGATAMHFAAS 250 Query: 246 QPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHL 298 + + ++ + LL + E+ + G TP A G + Q L Sbjct: 251 RGH----TKVLSWLLLHGA-------EISQDLWGGTPLHDAAENGELECCQIL 292 >3EU9-A nrPDB Length = 240 Score = 107 bits (266), Expect = 2e-23, Method: Composition-based stats. Identities = 35/164 (21%), Positives = 69/164 (42%), Gaps = 19/164 (11%) Query: 86 ESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPEL 145 +PL A ++ ++ +++L+K+ G + G + +H+AA + + L+ ++ Sbjct: 77 STPLHWATRQGHLSMVVQLMKY-GADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDV 135 Query: 146 VFEPMTSELYEGQTALHIAVINQN-VNLVRALLARGASVSARATGSVFHYRPHNLIYYGE 204 G T L A + V+ R LL SV+ Y+ Sbjct: 136 DMM-----DQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDK------------YHKN 178 Query: 205 HPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPN 248 L +A G+ ++ LL+E GA++ AQ+ G + L + + N Sbjct: 179 TALHWAVLAGNTTVISLLLEAGANVDAQNIKGESALDLAKQRKN 222 Score = 96.7 bits (239), Expect = 3e-20, Method: Composition-based stats. Identities = 56/227 (24%), Positives = 86/227 (37%), Gaps = 32/227 (14%) Query: 80 QQKRIWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAM-GETALHIAALYDNLEAAMVL 138 Q + + L AA N + L+K +G V Q G T LH A +L + L Sbjct: 37 QPDKENVTLLHWAAINNRID-LVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQL 95 Query: 139 MEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHN 198 M+ + EG + +H+A + ++V L+A+G V Sbjct: 96 MKYGADPSL-----IDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQN--------- 141 Query: 199 LIYYGEHPLSFAAC-VGSEEIVRLLIEHGADIRAQDS-LGNTVLHILILQPNKTFACQMY 256 G PL +AA S + RLL+ + D NT LH +L N T + Sbjct: 142 ----GMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTT----VI 193 Query: 257 NLLLSYDGGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKRK 303 +LLL + N +G + LA N+ M HL + R+ Sbjct: 194 SLLLEAGANVDAQ------NIKGESALDLAKQRKNVWMINHLQEARQ 234 Score = 92.5 bits (228), Expect = 6e-19, Method: Composition-based stats. Identities = 41/204 (20%), Positives = 70/204 (34%), Gaps = 25/204 (12%) Query: 103 KLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALH 162 + L G +V Q T LH AA+ + ++ + + T LH Sbjct: 26 RELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGGDLN----STPLH 81 Query: 163 IAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLL 222 A ++++V L+ GA P + G + AA G IV L Sbjct: 82 WATRQGHLSMVVQLMKYGAD-------------PSLIDGEGCSCIHLAAQFGHTSIVAYL 128 Query: 223 IEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGLTP 282 I G D+ D G T L + + + LLL+++ +L T Sbjct: 129 IAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTR---LLLTFNVSVNLGD-----KYHKNTA 180 Query: 283 FKLAGVEGNIVMFQHLMQKRKHIQ 306 A + GN + L++ ++ Sbjct: 181 LHWAVLAGNTTVISLLLEAGANVD 204 Score = 55.9 bits (133), Expect = 6e-08, Method: Composition-based stats. Identities = 25/102 (24%), Positives = 46/102 (45%), Gaps = 6/102 (5%) Query: 76 QNLLQQKRIWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGE-TALHIAALYDNLEA 134 Q++ + +PL+ AA + +LL V+ + TALH A L N Sbjct: 133 QDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTV 192 Query: 135 AMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRAL 176 +L+EA + ++ +G++AL +A +NV ++ L Sbjct: 193 ISLLLEAGANV-----DAQNIKGESALDLAKQRKNVWMINHL 229 Score = 44.3 bits (103), Expect = 2e-04, Method: Composition-based stats. Identities = 31/158 (19%), Positives = 52/158 (32%), Gaps = 28/158 (17%) Query: 210 AACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLK 269 A G E R L+E G D+R D T+LH + N Y + Sbjct: 16 ATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAI--NNRIDLVKYYI-------SKGA 66 Query: 270 SLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKRK-------------HIQWTYGPLTSTL 316 ++ + + TP A +G++ M LM+ H+ +G + Sbjct: 67 IVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVA 126 Query: 317 Y------DLTEIDSSGDDQSLLELIVTTKKREARQILD 348 Y D+ +D +G + T R +L Sbjct: 127 YLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLT 164 >4OT9-A nrPDB Length = 359 Score = 102 bits (253), Expect = 9e-22, Method: Composition-based stats. Identities = 53/263 (20%), Positives = 91/263 (34%), Gaps = 34/263 (12%) Query: 78 LLQQKRIWESPLLLAAKENNVQALIKLL-KFEGCE----VHQKGAMGETALHIAALYDNL 132 L Q ++PL LA + +++ + V+ + +T LH+A + Sbjct: 75 LTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQT 134 Query: 133 EAAMVLMEAAPELVFEPMTSELYEGQTALHIA--VINQNVNLVRALLARGASVSARATGS 190 L+ + G +A+H+A L+RALL GA Sbjct: 135 SVVSFLLRVGADPALL-----DRHGDSAMHLALRAGAGAPELLRALLQSGA--------P 181 Query: 191 VFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSL-GNTVLHILILQPNK 249 H + G +P+ A S E + LL++ GA++ A + G T LH+ Sbjct: 182 AVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEEL 241 Query: 250 TFACQMYNLLLSYDGGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKRKHI---- 305 + L + G TP LA G + + L++ I Sbjct: 242 GLVTHLVTKLRANVNARTFA---------GNTPLHLAAGLGYPTLTRLLLKAGADIHAEN 292 Query: 306 QWTYGPLTSTLYDLTEIDSSGDD 328 + PL S ++ DS G + Sbjct: 293 EEPLCPLPSPPTSDSDSDSEGPE 315 Score = 73.6 bits (179), Expect = 3e-13, Method: Composition-based stats. Identities = 41/205 (20%), Positives = 78/205 (38%), Gaps = 13/205 (6%) Query: 150 MTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSF 209 +T++ G T LH+A+I+ +++ ++ A+ G V + + + PL Sbjct: 75 LTAQDENGDTPLHLAIIHGQTSVIEQIVY--VIHHAQDLGVV-----NLTNHLHQTPLHL 127 Query: 210 AACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLK 269 A G +V L+ GAD D G++ +H+ + A ++ LL + Sbjct: 128 AVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAG--AGAPELLRALLQSGAPA-VP 184 Query: 270 SLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKRKHIQWTYGPLTSTLYDLTEIDSSGDDQ 329 L +P+ +GL P LA + L+ ++ T T L + Sbjct: 185 QLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLAT--EMEELG 242 Query: 330 SLLELIVTTK-KREARQILDQTPVK 353 + L+ + AR TP+ Sbjct: 243 LVTHLVTKLRANVNARTFAGNTPLH 267 Score = 53.2 bits (126), Expect = 4e-07, Method: Composition-based stats. Identities = 29/138 (21%), Positives = 48/138 (34%), Gaps = 18/138 (13%) Query: 174 RALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVR---LLIEHGAD-- 228 RALL G + ARA + + G+ PL A G ++ +I H D Sbjct: 53 RALLDYGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLG 112 Query: 229 -IRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGLTPFKLA- 286 + + L T LH+ ++ + L G D + + G + LA Sbjct: 113 VVNLTNHLHQTPLHLAVITGQTSVVS-----FLLRVGAD-----PALLDRHGDSAMHLAL 162 Query: 287 -GVEGNIVMFQHLMQKRK 303 G + + L+Q Sbjct: 163 RAGAGAPELLRALLQSGA 180 Score = 50.5 bits (119), Expect = 3e-06, Method: Composition-based stats. Identities = 22/125 (17%), Positives = 42/125 (33%), Gaps = 28/125 (22%) Query: 81 QKRIWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLME 140 +++ + L LA + + + L+ V+ + G T LH+AA +L++ Sbjct: 224 ERQGGRTALHLATEMEELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLK 283 Query: 141 AAPELVF------------------------EPMTSELYEGQTALHIAVINQNVNLVRAL 176 A ++ E T + G T L + + V+ L Sbjct: 284 AGADIHAENEEPLCPLPSPPTSDSDSDSEGPEKDTRSSFRGHTPLDLTCSTK----VKTL 339 Query: 177 LARGA 181 L A Sbjct: 340 LLNAA 344 >3ZKJ-A nrPDB Length = 261 Score = 94.4 bits (233), Expect = 1e-19, Method: Composition-based stats. Identities = 50/218 (22%), Positives = 83/218 (38%), Gaps = 36/218 (16%) Query: 87 SPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 SP+ AA + +L L+ +G V+ A + LH A L +L +L++ ++ Sbjct: 5 SPMHEAAIHGHQLSLRNLI-SQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQV- 62 Query: 147 FEPMTSELYEGQTALHIAVINQNVNLVRALLARGASV----------SARATGSVFHYRP 196 +T++ T L A ++ + + V LL GASV A Sbjct: 63 -NGVTADW---HTPLFNACVSGSWDCVNLLLQHGASVQPESDLASPIHEAARRGHVECVN 118 Query: 197 HNLIYYGE---------HPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQP 247 + Y G PL A V+ L+E GAD+ Q ++ LH + Sbjct: 119 SLIAYGGNIDHKISHLGTPLYLACENQQRACVKKLLESGADVN-QGKGQDSPLHAVARTA 177 Query: 248 NKTFACQMYNLLLSYDGGDHLKSLELVPNNQGLTPFKL 285 ++ AC L D G ++ N +G P +L Sbjct: 178 SEELAC------LLMDFGADTQA----KNAEGKRPVEL 205 Score = 82.5 bits (202), Expect = 7e-16, Method: Composition-based stats. Identities = 39/159 (24%), Positives = 66/159 (41%), Gaps = 21/159 (13%) Query: 85 WESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPE 144 W +PL A + + LL G V + + +H AA ++E L+ Sbjct: 69 WHTPLFNACVSGSWDCVN-LLLQHGASVQPESDLAS-PIHEAARRGHVECVNSLIAYGGN 126 Query: 145 LVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGE 204 + + G T L++A NQ V+ LL GA V+ + G + Sbjct: 127 IDH----KISHLG-TPLYLACENQQRACVKKLLESGADVN-QGKGQ-------------D 167 Query: 205 HPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHIL 243 PL A SEE+ LL++ GAD +A+++ G + ++ Sbjct: 168 SPLHAVARTASEELACLLMDFGADTQAKNAEGKRPVELV 206 Score = 82.5 bits (202), Expect = 7e-16, Method: Composition-based stats. Identities = 39/191 (20%), Positives = 74/191 (38%), Gaps = 29/191 (15%) Query: 120 ETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLAR 179 + +H AA++ + + L+ + +T++ + LH A + +++ V+ LL Sbjct: 4 WSPMHEAAIHGHQLSLRNLISQGWAVNI--ITADH---VSPLHEACLGGHLSCVKILLKH 58 Query: 180 GASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTV 239 GA V+ + PL A GS + V LL++HGA ++ + L + Sbjct: 59 GAQVN-------------GVTADWHTPLFNACVSGSWDCVNLLLQHGASVQPESDLA-SP 104 Query: 240 LHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLM 299 +H + + N L++Y G K L TP LA + L+ Sbjct: 105 IHEAARRGHVECV----NSLIAYGGNIDHKISHLG------TPLYLACENQQRACVKKLL 154 Query: 300 QKRKHIQWTYG 310 + + G Sbjct: 155 ESGADVNQGKG 165 Score = 65.5 bits (158), Expect = 9e-11, Method: Composition-based stats. Identities = 32/160 (20%), Positives = 59/160 (36%), Gaps = 24/160 (15%) Query: 158 QTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEE 217 + +H A I+ + +R L+++G +V+ V PL A G Sbjct: 4 WSPMHEAAIHGHQLSLRNLISQGWAVNIITADHV-------------SPLHEACLGGHLS 50 Query: 218 IVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNN 277 V++L++HGA + + +T L + + NLLL + P + Sbjct: 51 CVKILLKHGAQVNGVTADWHTPLFNACVSGSWDCV----NLLLQHGASVQ-------PES 99 Query: 278 QGLTPFKLAGVEGNIVMFQHLMQKRKHIQWTYGPLTSTLY 317 +P A G++ L+ +I L + LY Sbjct: 100 DLASPIHEAARRGHVECVNSLIAYGGNIDHKISHLGTPLY 139 Score = 54.7 bits (130), Expect = 1e-07, Method: Composition-based stats. Identities = 22/108 (20%), Positives = 43/108 (39%), Gaps = 7/108 (6%) Query: 79 LQQKRIWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVL 138 +Q + SP+ AA+ +V+ + L+ + G H+ +G T L++A L Sbjct: 95 VQPESDLASPIHEAARRGHVECVNSLIAYGGNIDHKISHLG-TPLYLACENQQRACVKKL 153 Query: 139 MEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSAR 186 +E+ ++ + LH + L L+ GA A+ Sbjct: 154 LESGADVNQGKGQD------SPLHAVARTASEELACLLMDFGADTQAK 195 Score = 31.2 bits (69), Expect = 1.6, Method: Composition-based stats. Identities = 14/117 (11%), Positives = 44/117 (37%), Gaps = 14/117 (11%) Query: 238 TVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQH 297 + +H + ++ L + ++ ++ + ++P A + G++ + Sbjct: 5 SPMHEAAIHGHQ---------LSLRNLISQGWAVNIITADH-VSPLHEACLGGHLSCVKI 54 Query: 298 LMQKRKHIQWTYGPLTSTLYDLTEIDSSGDDQSLLELIVTTKKREARQILDQTPVKE 354 L++ + + L++ + S D +LL + + E+ +P+ E Sbjct: 55 LLKHGAQVNGVTADWHTPLFN-ACVSGSWDCVNLLLQHGASVQPESD---LASPIHE 107 >6CUD-A nrPDB Length = 806 Score = 94.0 bits (232), Expect = 2e-19, Method: Composition-based stats. Identities = 99/668 (14%), Positives = 204/668 (30%), Gaps = 139/668 (20%) Query: 89 LLLAAKENNVQALIKLLK-FEGCEVHQKGAMGETALHIAALYDNLEAAMVLME------- 140 L AA+ N+ + K+L+ + V+ MG+ AL +A ++LE +L++ Sbjct: 31 FLDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARI 90 Query: 141 --------------------------AAPELVFEPMTSE---------LYEGQ------T 159 A+ L P E +G T Sbjct: 91 GDALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAYDEDGTRFSPDIT 150 Query: 160 ALHIAVINQNVNLVRALLARGASVSAR-----ATGSVFHYRPHNLI---------YYG-E 204 + +A Q +V LL +GA + G + H+ Y G Sbjct: 151 PIILAAHCQKYEVVHMLLMKGARIERPHDYFCKCGDCMEKQRHDSFSHSRSRINAYKGLA 210 Query: 205 HPLSFAACVGSEEIVRLLIEHG-ADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD 263 P + + L + + A + + L +Q K F + +L Sbjct: 211 SPAYLSLSSEDPVLTALELSNELAKLANIEKEFKNDYRKLSMQC-KDFVVGVLDLC---- 265 Query: 264 GGDHLKSLELVPNNQGLT--PFKLAGVEGNIVMFQHLMQKRKHIQWTYGPLTSTLYDLTE 321 + +E + N + P ++ + ++ + ++ + L + Sbjct: 266 --RDSEEVEAILNGDLESAEPLEVHRHKASLSRVKLAIKYEVKKFVAHPNCQQQLLTI-- 321 Query: 322 IDSSGDDQSLL-ELIVTTKKREARQILDQTPVKELVSLKW----KRYGR--PYFCVLGAI 374 ++ S L E + K + P L W R G+ + Sbjct: 322 ---WYENLSGLREQTIAIKCLVVLVVALGLPF--LAIGYWIAPCSRLGKILRSPFMKFVA 376 Query: 375 YVLYIICFTMCCVYRPLKPRITNRTNPRDNTLLQQKLLQEAYVTPKDDLRLVGELVSIVG 434 + I F V+ T P K + T E++ +V Sbjct: 377 HAASFIIFLGLLVFNASDRFEGITTLPNITVTDYPKQIFRVKTTQFTWT----EMLIMVW 432 Query: 435 AVIILLVEIPDIFRLGVTRFFGQ----------TILGGPF--HVIIVTYAF--------- 473 + ++ E +++ G + Q +I F + A Sbjct: 433 VLGMMWSECKELWLEGPREYILQLWNVLDFGMLSIFIAAFTARFLAFLQATKAQQYVDSY 492 Query: 474 --------MVLVTMVMRLT-NSDGEVV---------PMSFALVLGWCNVMYFARGFQMLG 515 + L + T D + + A+VL + + Y + G Sbjct: 493 VQESDLSEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSRIAYILPANESFG 552 Query: 516 PFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQ----TEDPDELGHFYDYPMALF- 570 P I + + + D+ +F L +V F +I++ + + LF Sbjct: 553 PLQISLGRTV-KDIFKFMVLFIMVFFAFMIGMFILYSYYLGAKVNAAFTTVEESFKTLFW 611 Query: 571 STFELF-LTIIDGPANYDVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERD 629 S F L +T + ++ + + + Y + + +++LN+LIAM+ ++ + + D Sbjct: 612 SIFGLSEVTSVVLKYDHKF-IENIGYVLYGIYNVTMVVVLLNMLIAMINSSYQEIEDDSD 670 Query: 630 ELWRAQVV 637 W+ Sbjct: 671 VEWKFARS 678 >1WG0-A nrPDB Length = 243 Score = 92.1 bits (227), Expect = 9e-19, Method: Composition-based stats. Identities = 45/204 (22%), Positives = 70/204 (34%), Gaps = 22/204 (10%) Query: 88 PLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVF 147 PL A EN + +LL + + QK G LH + + E L+ + Sbjct: 5 PLHQACMENEFFKVQELLHSKPSLLLQKDQDGRIPLHWSVSFQAHEITSFLLSKMENVNL 64 Query: 148 EPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPL 207 + + G T HIA N+ +V++L + + G L Sbjct: 65 DDYPDD--SGWTPFHIACSVGNLEVVKSLYD-----------RPLKPDLNKITNQGVTCL 111 Query: 208 SFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDH 267 A E+ + LIE+GA +R +D LH + + L Sbjct: 112 HLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHRAASVGSLKLIELLCGL--------- 162 Query: 268 LKSLELVPNNQGLTPFKLAGVEGN 291 KS + QG TP A EG+ Sbjct: 163 GKSAVNWQDKQGWTPLFHALAEGH 186 Score = 84.0 bits (206), Expect = 2e-16, Method: Composition-based stats. Identities = 45/183 (24%), Positives = 70/183 (38%), Gaps = 19/183 (10%) Query: 78 LLQQKRIWESPLLLAAKENNVQALIKLL-KFEGCEVHQ-KGAMGETALHIAALYDNLEAA 135 LLQ+ + PL + + LL K E + G T HIA NLE Sbjct: 29 LLQKDQDGRIPLHWSVSFQAHEITSFLLSKMENVNLDDYPDDSGWTPFHIACSVGNLEVV 88 Query: 136 MVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYR 195 L + + + +G T LH+AV + + + L+ GASV + Sbjct: 89 KSLYDR---PLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASVRIKDK------- 138 Query: 196 PHNLIYYGEHPLSFAACVGSEEIVRLLIEHGAD-IRAQDSLGNTVLHILILQPNKTFACQ 254 + + PL AA VGS +++ LL G + QD G T L + + + A Sbjct: 139 ------FNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVL 192 Query: 255 MYN 257 + Sbjct: 193 LVE 195 Score = 74.8 bits (182), Expect = 1e-13, Method: Composition-based stats. Identities = 34/170 (20%), Positives = 64/170 (37%), Gaps = 21/170 (12%) Query: 85 WESPLLLAAKENNVQALIKLL-KFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAP 143 +P +A N++ + L + ++++ G T LH+A E + L+E Sbjct: 72 GWTPFHIACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGA 131 Query: 144 ELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARG-ASVSARATGSVFHYRPHNLIYY 202 + + Q LH A ++ L+ L G ++V+ + Sbjct: 132 SVRIK-----DKFNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQ------------- 173 Query: 203 GEHPLSFAACVGSEEIVRLLIE-HGADIRAQDSLGNTVLHILILQPNKTF 251 G PL A G + LL+E +GA+ D+ G + + + K F Sbjct: 174 GWTPLFHALAEGHGDAAVLLVEKYGAEYDLVDNKGAKAEDVALNEQVKKF 223 Score = 49.3 bits (116), Expect = 7e-06, Method: Composition-based stats. Identities = 31/149 (20%), Positives = 52/149 (34%), Gaps = 23/149 (15%) Query: 160 ALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIV 219 LH A + V+ LL + S+ + + G PL ++ + EI Sbjct: 5 PLHQACMENEFFKVQELL--------HSKPSLLLQKDQD----GRIPLHWSVSFQAHEIT 52 Query: 220 RLLIEHGADIRAQD---SLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPN 276 L+ ++ D G T HI N +Y+ L D L + N Sbjct: 53 SFLLSKMENVNLDDYPDDSGWTPFHIACSVGNLEVVKSLYDRPLKPD-------LNKITN 105 Query: 277 NQGLTPFKLAGVEGNIVMFQHLMQKRKHI 305 QG+T LA + + Q L++ + Sbjct: 106 -QGVTCLHLAVGKKWFEVSQFLIENGASV 133 >1BD8-A nrPDB Length = 156 Score = 87.1 bits (214), Expect = 3e-17, Method: Composition-based stats. Identities = 31/165 (18%), Positives = 62/165 (37%), Gaps = 20/165 (12%) Query: 92 AAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMT 151 AA +VQ + +LL E G+TAL + ++ + A+ L++ Sbjct: 9 AAARGDVQEVRRLLHRELVHPDALNRFGKTALQV-MMFGSTAIALELLKQGA-----SPN 62 Query: 152 SELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAA 211 + G + +H A ++ ++ L+ GA V+ G P+ A Sbjct: 63 VQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGT-------------GALPIHLAV 109 Query: 212 CVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMY 256 G +V L +D+ +D+ G T L + + + + + Sbjct: 110 QEGHTAVVSFL-AAESDLHRRDARGLTPLELALQRGAQDLVDILQ 153 Score = 66.3 bits (160), Expect = 4e-11, Method: Composition-based stats. Identities = 23/96 (23%), Positives = 36/96 (37%), Gaps = 7/96 (7%) Query: 81 QKRIWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLME 140 Q SP+ AA+ + L K+L G +V+ G +H+A + L Sbjct: 64 QDTSGTSPVHDAARTGFLDTL-KVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFL-- 120 Query: 141 AAPELVFEPMTSELYEGQTALHIAVINQNVNLVRAL 176 A E + G T L +A+ +LV L Sbjct: 121 -AAESDLHRRDA---RGLTPLELALQRGAQDLVDIL 152 Score = 62.8 bits (151), Expect = 6e-10, Method: Composition-based stats. Identities = 31/143 (21%), Positives = 57/143 (39%), Gaps = 21/143 (14%) Query: 83 RIWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAA 142 R ++ L + + ++LLK +G + + G + +H AA L+ VL+E Sbjct: 34 RFGKTALQVMMF-GSTAIALELLK-QGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHG 91 Query: 143 PELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYY 202 ++ T G +H+AV + +V L A + + R Sbjct: 92 ADVNVPDGT-----GALPIHLAVQEGHTAVVSFLAAE-SDLHRRDAR------------- 132 Query: 203 GEHPLSFAACVGSEEIVRLLIEH 225 G PL A G++++V +L H Sbjct: 133 GLTPLELALQRGAQDLVDILQGH 155 >1BLX-B nrPDB Length = 166 Score = 78.6 bits (192), Expect = 9e-15, Method: Composition-based stats. Identities = 32/160 (20%), Positives = 62/160 (38%), Gaps = 20/160 (12%) Query: 92 AAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMT 151 AA +VQ + +LL E G+TAL + ++ + A+ L++ Sbjct: 15 AAARGDVQEVRRLLHRELVHPDALNRFGKTALQV-MMFGSPAVALELLKQGA-----SPN 68 Query: 152 SELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAA 211 + G + +H A ++ ++ L+ GA V+A + G P+ A Sbjct: 69 VQDASGTSPVHDAARTGFLDTLKVLVEHGADVNALDST-------------GSLPIHLAI 115 Query: 212 CVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTF 251 G +V L +D+ +D+ G T L + + + Sbjct: 116 REGHSSVVSFL-APESDLHHRDASGLTPLELARQRGAQNL 154 Score = 62.8 bits (151), Expect = 5e-10, Method: Composition-based stats. Identities = 24/96 (25%), Positives = 37/96 (38%), Gaps = 7/96 (7%) Query: 81 QKRIWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLME 140 Q SP+ AA+ + L K+L G +V+ + G +H+A + L Sbjct: 70 QDASGTSPVHDAARTGFLDTL-KVLVEHGADVNALDSTGSLPIHLAIREGHSSVVSFL-- 126 Query: 141 AAPELVFEPMTSELYEGQTALHIAVINQNVNLVRAL 176 APE + G T L +A NL+ L Sbjct: 127 -APESDLHHRDAS---GLTPLELARQRGAQNLMDIL 158 Score = 58.6 bits (140), Expect = 1e-08, Method: Composition-based stats. Identities = 25/121 (20%), Positives = 48/121 (39%), Gaps = 19/121 (15%) Query: 105 LKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIA 164 L +G + + A G + +H AA L+ VL+E ++ + G +H+A Sbjct: 60 LLKQGASPNVQDASGTSPVHDAARTGFLDTLKVLVEHGADV-----NALDSTGSLPIHLA 114 Query: 165 VINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIE 224 + + ++V L A + + R G PL A G++ ++ +L Sbjct: 115 IREGHSSVVSFL-APESDLHHRDAS-------------GLTPLELARQRGAQNLMDILQG 160 Query: 225 H 225 H Sbjct: 161 H 161 >6CV9-A nrPDB Length = 842 Score = 78.2 bits (191), Expect = 1e-14, Method: Composition-based stats. Identities = 26/150 (17%), Positives = 61/150 (40%), Gaps = 8/150 (5%) Query: 494 SFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQ- 552 + A+VL + + Y + GP I + + + D+ +F + +V + F + ++ Sbjct: 511 AIAVVLSFSRIAYILPANESFGPLQISLGRTV-KDIFKFMVIFIMVFVAFMIGMFNLYSY 569 Query: 553 ---TEDPDELGHFYDYPMALF-STFELFLTIIDGPANYDVDL-PFMYSITYAAFAIIATL 607 + + + LF + F L + NY+ + + Y + + + Sbjct: 570 YIGAKQNEAFTTVEESFKTLFWAIFGLS-EVKSVVINYNHKFIENIGYVLYGVYNVTMVI 628 Query: 608 LMLNLLIAMMGDTHWRVAHERDELWRAQVV 637 ++LN+LIAM+ + + + D W+ Sbjct: 629 VLLNMLIAMINSSFQEIEDDADVEWKFARA 658 Score = 55.9 bits (133), Expect = 6e-08, Method: Composition-based stats. Identities = 34/156 (21%), Positives = 56/156 (35%), Gaps = 23/156 (14%) Query: 89 LLLAAKENNVQALIKLLKFEGC-EVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVF 147 L AA+ N+ + K+L+ V+ MG+ AL +A ++LE +L++ Sbjct: 13 FLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKK------ 66 Query: 148 EPMTSELYEGQTALHIAVINQNVNLVRALLARGA------------SVSARATGSVFHYR 195 L AL +A+ V +V A+L A + + Sbjct: 67 ----ENLSRVGDALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDE 122 Query: 196 PHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRA 231 + P+ AA EIV L+ GA I Sbjct: 123 DGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIER 158 Score = 52.4 bits (124), Expect = 7e-07, Method: Composition-based stats. Identities = 36/184 (19%), Positives = 60/184 (32%), Gaps = 39/184 (21%) Query: 123 LHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGAS 182 AA Y N+ ++E E + Y GQ AL +AV N+++ + LL + Sbjct: 13 FLDAAEYGNIPVVRKMLE---ECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKK--- 66 Query: 183 VSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHI 242 NL G+ L A G IV ++ H A A+ + Sbjct: 67 --------------ENLSRVGDA-LLLAISKGYVRIVEAILNHPA--FAEGKR------L 103 Query: 243 LILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKR 302 + +YD + + +TP LA + L++K Sbjct: 104 ATSPSQSELQ---QDDFYAYDE-------DGTRFSHDVTPIILAAHCQEYEIVHTLLRKG 153 Query: 303 KHIQ 306 I+ Sbjct: 154 ARIE 157 >1G3N-B nrPDB Length = 168 Score = 77.8 bits (190), Expect = 2e-14, Method: Composition-based stats. Identities = 40/173 (23%), Positives = 62/173 (35%), Gaps = 21/173 (12%) Query: 85 WESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPE 144 W + L AA +++ L LL+ Q G G TAL + L N E A L+ Sbjct: 5 WGNELASAAARGDLEQLTSLLQNNVNVNAQNG-FGRTALQVMKL-GNPEIARRLLLRGAN 62 Query: 145 LVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGE 204 + T G +H A ++ ++ LL A V+ G Sbjct: 63 PDLKDRT-----GFAVIHDAARAGFLDTLQTLLEFQADVNIEDN-------------EGN 104 Query: 205 HPLSFAACVGSEEIVRLLIEHGAD-IRAQDSLGNTVLHILILQPNKTFACQMY 256 PL AA G +V L++H A + ++ G+T + L M Sbjct: 105 LPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQ 157 Score = 69.7 bits (169), Expect = 5e-12, Method: Composition-based stats. Identities = 24/101 (23%), Positives = 44/101 (43%), Gaps = 5/101 (4%) Query: 81 QKRIWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLME 140 + R + + AA+ + L LL+F+ +V+ + G LH+AA +L L++ Sbjct: 66 KDRTGFAVIHDAARAGFLDTLQTLLEFQ-ADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124 Query: 141 AAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGA 181 V ++G TA +A + +V + A GA Sbjct: 125 HTASNVGHR----NHKGDTACDLARLYGRNEVVSLMQANGA 161 Score = 64.7 bits (156), Expect = 1e-10, Method: Composition-based stats. Identities = 32/138 (23%), Positives = 50/138 (36%), Gaps = 18/138 (13%) Query: 90 LLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEP 149 L K N + +LL G K G +H AA L+ L+E ++ Sbjct: 42 LQVMKLGNPEIARRLLL-RGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADV---- 96 Query: 150 MTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSF 209 E EG LH+A ++ +V L+ AS + + G+ Sbjct: 97 -NIEDNEGNLPLHLAAKEGHLRVVEFLVKHTAS------------NVGHRNHKGDTACDL 143 Query: 210 AACVGSEEIVRLLIEHGA 227 A G E+V L+ +GA Sbjct: 144 ARLYGRNEVVSLMQANGA 161 Score = 59.3 bits (142), Expect = 6e-09, Method: Composition-based stats. Identities = 38/173 (21%), Positives = 65/173 (37%), Gaps = 28/173 (16%) Query: 123 LHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGAS 182 L AA +LE L++ + + G+TAL + + N + R LL RGA+ Sbjct: 9 LASAAARGDLEQLTSLLQNNVNVNAQNG-----FGRTALQV-MKLGNPEIARRLLLRGAN 62 Query: 183 VSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHI 242 + G + AA G + ++ L+E AD+ +D+ GN LH+ Sbjct: 63 PDLKDRT-------------GFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHL 109 Query: 243 LILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGLTPFKLAGVEGNIVMF 295 + + + H S N++G T LA + G + Sbjct: 110 AAKEGHLRVVEFLVK---------HTASNVGHRNHKGDTACDLARLYGRNEVV 153 Score = 55.9 bits (133), Expect = 7e-08, Method: Composition-based stats. Identities = 33/173 (19%), Positives = 62/173 (35%), Gaps = 24/173 (13%) Query: 161 LHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVR 220 L A ++ + +LL + + +G L +G+ EI R Sbjct: 9 LASAAARGDLEQLTSLLQ-------------NNVNVNAQNGFGRTALQVMK-LGNPEIAR 54 Query: 221 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGL 280 L+ GA+ +D G V+H F + LL ++ + +N+G Sbjct: 55 RLLLRGANPDLKDRTGFAVIHDAARAG---FLDTLQTLL-------EFQADVNIEDNEGN 104 Query: 281 TPFKLAGVEGNIVMFQHLMQKRKHIQWTYGPLTSTLYDLTEIDSSGDDQSLLE 333 P LA EG++ + + L++ T DL + + SL++ Sbjct: 105 LPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQ 157 >6EMK-G nrPDB Length = 426 Score = 75.9 bits (185), Expect = 6e-14, Method: Composition-based stats. Identities = 33/160 (20%), Positives = 66/160 (41%), Gaps = 16/160 (10%) Query: 89 LLLAAKENNVQALIKLLKFEGCEVHQKGA-MGETALHIAALYDNLEAAMVLMEAAPELVF 147 L A E N+ + +LL+ + + G ++LH A+ + + L++ + Sbjct: 9 LREAIIEGNLLIVKRLLRRNPDLLTNIDSENGWSSLHYASYHGRYLICVYLIQLGHDKHE 68 Query: 148 EPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPL 207 T ++G T +H+A++ + + LL + F ++ G P+ Sbjct: 69 LIKT---FKGNTCVHLALMKGHEQTLHLLLQQ------------FPRFINHRGENGRAPI 113 Query: 208 SFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQP 247 A + + LLI GAD+ D+ G+T LH+ + Sbjct: 114 HIACMNDYYQCLSLLIGVGADLWVMDTNGDTPLHVCLEYG 153 Score = 63.6 bits (153), Expect = 3e-10, Method: Composition-based stats. Identities = 35/182 (19%), Positives = 63/182 (34%), Gaps = 25/182 (13%) Query: 123 LHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGAS 182 L A + NL L+ P+L+ + G ++LH A + + L+ G Sbjct: 9 LREAIIEGNLLIVKRLLRRNPDLLT---NIDSENGWSSLHYASYHGRYLICVYLIQLGHD 65 Query: 183 VSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEH-GADIRAQDSLGNTVLH 241 + G + A G E+ + LL++ I + G +H Sbjct: 66 -----------KHELIKTFKGNTCVHLALMKGHEQTLHLLLQQFPRFINHRGENGRAPIH 114 Query: 242 ILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQK 301 I + N + C L L G L ++ G TP + G+I + L+ + Sbjct: 115 IACM--NDYYQC----LSLLIGVGADLWVMD----TNGDTPLHVCLEYGSISCMKMLLNE 164 Query: 302 RK 303 + Sbjct: 165 GE 166 Score = 58.6 bits (140), Expect = 1e-08, Method: Composition-based stats. Identities = 26/134 (19%), Positives = 53/134 (39%), Gaps = 9/134 (6%) Query: 74 DEQNLLQQKRIWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLE 133 D+ L++ + + + LA + + Q L LL+ ++ +G G +HIA + D + Sbjct: 65 DKHELIKTFK-GNTCVHLALMKGHEQTLHLLLQQFPRFINHRGENGRAPIHIACMNDYYQ 123 Query: 134 AAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGA---SVSARATGS 190 +L+ +L G T LH+ + +++ ++ LL G + R G+ Sbjct: 124 CLSLLIGVGADLWVMDTN-----GDTPLHVCLEYGSISCMKMLLNEGEVSLDDNVRDKGN 178 Query: 191 VFHYRPHNLIYYGE 204 G Sbjct: 179 WKPIDVAQTFEVGN 192 >3LJN-A nrPDB Length = 364 Score = 74.8 bits (182), Expect = 1e-13, Method: Composition-based stats. Identities = 47/240 (19%), Positives = 88/240 (36%), Gaps = 25/240 (10%) Query: 89 LLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFE 148 + +AA++ + +L++ G + G TALH+A + ++ A L Sbjct: 24 IHVAARKGQTDEVRRLIE-TGVSPTIQNRFGCTALHLACKFGCVDTAKYLASVGE----- 77 Query: 149 PMTSELYEGQTALHIAVINQNVNLVRALLARGAS---------VSARATGSVFHYRPHNL 199 L+ GQ +H+AV+ +LV AL+ GA ++ V H Sbjct: 78 --VHSLWHGQKPIHLAVMANKTDLVVALVE-GAKERGQMPESLLNECDEREVNEIGSHVK 134 Query: 200 IYYGEHPLSFAACVG--SEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYN 257 G+ L + +G E++++L++ GA A+D T L + N+ M + Sbjct: 135 HCKGQTALHWCVGLGPEYLEMIKILVQLGASPTAKDKADETPLMRAMEFRNREALDLMMD 194 Query: 258 LLLSYDGGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKRKHIQWTYGPLTSTLY 317 + S N QG + A + + ++ + T LY Sbjct: 195 TVPSKSS-----LRLDYANKQGNSHLHWAILINWEDVAMRFVEMGIDVNMEDNEHTVPLY 249 Score = 67.4 bits (163), Expect = 2e-11, Method: Composition-based stats. Identities = 44/246 (17%), Positives = 78/246 (31%), Gaps = 53/246 (21%) Query: 81 QKRIWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLME 140 Q R + L LA K V L EVH G+ +H+A + + + + L+E Sbjct: 49 QNRFGCTALHLACKFGCVDTAKYL--ASVGEVHSL-WHGQKPIHLAVMANKTDLVVALVE 105 Query: 141 AAPE----------------LVFEPMTSELYEGQTALHIAVINQ--NVNLVRALLARGAS 182 A E + + +GQTALH V + +++ L+ GAS Sbjct: 106 GAKERGQMPESLLNECDEREVNEIGSHVKHCKGQTALHWCVGLGPEYLEMIKILVQLGAS 165 Query: 183 VSARATGSVFHYRPHNLIY-------------------------YGEHPLSFAACVGSEE 217 +A+ G L +A + E+ Sbjct: 166 PTAKDKADETPLMRAMEFRNREALDLMMDTVPSKSSLRLDYANKQGNSHLHWAILINWED 225 Query: 218 IVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNN 277 + +E G D+ +D+ L++ + M L + ++ P + Sbjct: 226 VAMRFVEMGIDVNMEDNEHTVPLYLSVR-------AAMVLLTKELLQKTDVFLIQACPYH 278 Query: 278 QGLTPF 283 G T Sbjct: 279 NGTTVL 284 >5D68-A nrPDB Length = 486 Score = 70.5 bits (171), Expect = 3e-12, Method: Composition-based stats. Identities = 37/166 (22%), Positives = 61/166 (36%), Gaps = 26/166 (15%) Query: 65 RRESWAQSRDEQNLLQQKRIW--ESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETA 122 ++E W +S ++R W + PL +A E + + L +LL E V+Q + Sbjct: 17 KQEKWQRSMSSVTE-DKERQWVDDFPLHRSACEGDSELLSRLL-SERFSVNQLDSDHWAP 74 Query: 123 LHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQ--TALHIAVINQNVNLVRALLARG 180 +H A Y +EA +L+E L GQ + LH A + +V+ LL Sbjct: 75 IHYACWYGKVEATRILLEKGK------CNPNLLNGQLSSPLHFAAGGGHAEIVQILLNH- 127 Query: 181 ASVSARATGSVFHYRPHNLIYYGEHPLSFAA--CVGSEEIVRLLIE 224 H G PL+ + E L++ Sbjct: 128 -----------PETDRHITDQQGRSPLNICEENKQNNWEEAAKLLK 162 Score = 65.5 bits (158), Expect = 8e-11, Method: Composition-based stats. Identities = 32/138 (23%), Positives = 46/138 (33%), Gaps = 18/138 (13%) Query: 122 ALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGA 181 LH +A + E L+ + S+ +H A V R LL +G Sbjct: 41 PLHRSACEGDSELLSRLLS--ERFSVNQLDSDH---WAPIHYACWYGKVEATRILLEKGK 95 Query: 182 SVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEHG-ADIRAQDSLGNTVL 240 P+ L PL FAA G EIV++L+ H D D G + L Sbjct: 96 C------------NPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPL 143 Query: 241 HILILQPNKTFACQMYNL 258 +I + L Sbjct: 144 NICEENKQNNWEEAAKLL 161 Score = 45.9 bits (107), Expect = 7e-05, Method: Composition-based stats. Identities = 25/131 (19%), Positives = 48/131 (36%), Gaps = 12/131 (9%) Query: 206 PLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGG 265 PL +AC G E++ L+ + DS +H +AC + + Sbjct: 41 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIH---------YACWYGKVEATRILL 91 Query: 266 DHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQK---RKHIQWTYGPLTSTLYDLTEI 322 + K + N Q +P A G+ + Q L+ +HI G + + + Sbjct: 92 EKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQ 151 Query: 323 DSSGDDQSLLE 333 ++ + LL+ Sbjct: 152 NNWEEAAKLLK 162 >3UI2-A nrPDB Length = 244 Score = 69.7 bits (169), Expect = 4e-12, Method: Composition-based stats. Identities = 38/140 (27%), Positives = 60/140 (42%), Gaps = 9/140 (6%) Query: 86 ESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPEL 145 E+P AA++ + QAL +LL E +V G TAL A + + +L EA +L Sbjct: 46 ETPWWTAARKADEQALSQLL--EDRDVDAVDENGRTALLFVAGLGSDKCVRLLAEAGADL 103 Query: 146 VFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGE- 204 M G TALH+A +V AL+ GA + + I Sbjct: 104 DHRDMR----GGLTALHMAAGYVRPEVVEALVELGADIEVEDERGLTALELAREILKTTP 159 Query: 205 --HPLSFAACVGSEEIVRLL 222 +P+ F +G E+++ +L Sbjct: 160 KGNPMQFGRRIGLEKVINVL 179 Score = 67.0 bits (162), Expect = 3e-11, Method: Composition-based stats. Identities = 33/124 (26%), Positives = 45/124 (36%), Gaps = 18/124 (14%) Query: 120 ETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLAR 179 ET AA + +A L+E + + G+TAL + VR L Sbjct: 46 ETPWWTAARKADEQALSQLLE------DRDVDAVDENGRTALLFVAGLGSDKCVRLLAEA 99 Query: 180 GASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTV 239 GA + R G L AA E+V L+E GADI +D G T Sbjct: 100 GADLDHRDMRG------------GLTALHMAAGYVRPEVVEALVELGADIEVEDERGLTA 147 Query: 240 LHIL 243 L + Sbjct: 148 LELA 151 Score = 55.9 bits (133), Expect = 7e-08, Method: Composition-based stats. Identities = 24/102 (23%), Positives = 44/102 (43%), Gaps = 7/102 (6%) Query: 66 RESWAQSRDEQNLLQQKRIWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMG-ETALH 124 ++ +Q +++++ + LL A + ++LL G ++ + G TALH Sbjct: 58 EQALSQLLEDRDVDAVDENGRTALLFVAGLGS-DKCVRLLAEAGADLDHRDMRGGLTALH 116 Query: 125 IAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVI 166 +AA Y E L+E ++ E G TAL +A Sbjct: 117 MAAGYVRPEVVEALVELGADIEV-----EDERGLTALELARE 153 Score = 37.4 bits (85), Expect = 0.027, Method: Composition-based stats. Identities = 22/103 (21%), Positives = 37/103 (35%), Gaps = 10/103 (9%) Query: 204 EHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD 263 E P AA E+ + L+E D+ A D G T L + + L + Sbjct: 46 ETPWWTAARKADEQALSQLLEDR-DVDAVDENGRTALLFVAGLGSDKCVR------LLAE 98 Query: 264 GGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKRKHIQ 306 G L ++ GLT +A + + L++ I+ Sbjct: 99 AGADLDHRDM---RGGLTALHMAAGYVRPEVVEALVELGADIE 138 >3EHQ-A nrPDB Length = 222 Score = 69.7 bits (169), Expect = 5e-12, Method: Composition-based stats. Identities = 28/107 (26%), Positives = 44/107 (41%), Gaps = 5/107 (4%) Query: 80 QQKRIWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLM 139 +Q ++PL AAK N+ L + V+ G TAL+ A + + +L Sbjct: 68 EQAESIDNPLHEAAKRGNLSWLRE-CLDNRVGVNGLDKAGSTALYWACHGGHKDIVEMLF 126 Query: 140 EAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSAR 186 + + G TALH A ++V+ LLA+GA R Sbjct: 127 TQ----PNIELNQQNKLGDTALHAAAWKGYADIVQLLLAKGARTDLR 169 Score = 62.8 bits (151), Expect = 5e-10, Method: Composition-based stats. Identities = 24/122 (19%), Positives = 41/122 (33%), Gaps = 17/122 (13%) Query: 122 ALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGA 181 LH AA NL ++ + G TAL+ A + ++V L + Sbjct: 76 PLHEAAKRGNLSWLRECLDN-----RVGVNGLDKAGSTALYWACHGGHKDIVEMLFTQ-- 128 Query: 182 SVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLH 241 + + G+ L AA G +IV+LL+ GA ++ Sbjct: 129 ----------PNIELNQQNKLGDTALHAAAWKGYADIVQLLLAKGARTDLRNIEKKLAFD 178 Query: 242 IL 243 + Sbjct: 179 MA 180 Score = 48.6 bits (114), Expect = 1e-05, Method: Composition-based stats. Identities = 21/103 (20%), Positives = 36/103 (34%), Gaps = 9/103 (8%) Query: 204 EHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD 263 ++PL AA G+ +R +++ + D G+T L+ +K +L Sbjct: 74 DNPLHEAAKRGNLSWLRECLDNRVGVNGLDKAGSTALYWACHGGHKDIVE-----MLFTQ 128 Query: 264 GGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKRKHIQ 306 L N G T A +G + Q L+ K Sbjct: 129 PNIELNQ----QNKLGDTALHAAAWKGYADIVQLLLAKGARTD 167 >3T9K-A nrPDB Length = 390 Score = 69.7 bits (169), Expect = 5e-12, Method: Composition-based stats. Identities = 38/156 (24%), Positives = 65/156 (41%), Gaps = 17/156 (10%) Query: 23 PGGVWHQPQPPKDS--AFHPMGWSLPKEKGLILCLWNKFCRWFHRRESWAQSRDEQNLLQ 80 PG + +P+PP + + HP G L + G L ++ A D N + Sbjct: 180 PGDLRSKPEPPSEDLGSLHP-GALLFRASGHPPSL-------PTMADALAHGAD-VNWVN 230 Query: 81 QKRIWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLME 140 + +PL+ A N++ A LL+ G V+Q + G LH A + + A + ++ Sbjct: 231 GGQDNATPLIQATAANSLLACEFLLQ-NGANVNQADSAGRGPLHHATILGHTGLACLFLK 289 Query: 141 AAPELVFEPMTSELYEGQTALHIAVINQNVNLVRAL 176 +L EG+ L IA+ N ++V L Sbjct: 290 RGADLGAR-----DSEGRDPLTIAMETANADIVTLL 320 Score = 65.1 bits (157), Expect = 1e-10, Method: Composition-based stats. Identities = 24/117 (20%), Positives = 42/117 (35%), Gaps = 16/117 (13%) Query: 139 MEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHN 198 + ++ + + T L A ++ LL GA+V+ + Sbjct: 220 LAHGADVNWVNGGQDN---ATPLIQATAANSLLACEFLLQNGANVNQADSA--------- 267 Query: 199 LIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQM 255 G PL A +G + L ++ GAD+ A+DS G L I + N + Sbjct: 268 ----GRGPLHHATILGHTGLACLFLKRGADLGARDSEGRDPLTIAMETANADIVTLL 320 Score = 30.5 bits (67), Expect = 2.8, Method: Composition-based stats. Identities = 22/118 (18%), Positives = 35/118 (29%), Gaps = 26/118 (22%) Query: 223 IEHGADIRAQD--SLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGL 280 + HGAD+ + T L I N AC LL + + G Sbjct: 220 LAHGADVNWVNGGQDNATPL-IQATAANSLLAC---EFLLQNGANVNQAD------SAGR 269 Query: 281 TPFKLAGVEGNIVMFQHLMQKRKHIQWTYGPLTSTLYDLTEIDSSGDDQSLLELIVTT 338 P A + G+ + +++ DL DS G D + + Sbjct: 270 GPLHHATILGHTGLACLFLKRGA--------------DLGARDSEGRDPLTIAMETAN 313 >3DEO-A nrPDB Length = 183 Score = 69.0 bits (167), Expect = 7e-12, Method: Composition-based stats. Identities = 38/140 (27%), Positives = 60/140 (42%), Gaps = 9/140 (6%) Query: 86 ESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPEL 145 E+P AA++ + QAL +LL E +V G TAL A + + +L EA +L Sbjct: 45 ETPWWTAARKADEQALSQLL--EDRDVDAVDENGRTALLFVAGLGSDKCVRLLAEAGADL 102 Query: 146 VFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGE- 204 M G TALH+A +V AL+ GA + + I Sbjct: 103 DHRDMR----GGLTALHMAAGYVRPEVVEALVELGADIEVEDERGLTALELAREILKTTP 158 Query: 205 --HPLSFAACVGSEEIVRLL 222 +P+ F +G E+++ +L Sbjct: 159 KGNPMQFGRRIGLEKVINVL 178 Score = 66.7 bits (161), Expect = 4e-11, Method: Composition-based stats. Identities = 33/124 (26%), Positives = 45/124 (36%), Gaps = 18/124 (14%) Query: 120 ETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLAR 179 ET AA + +A L+E + + G+TAL + VR L Sbjct: 45 ETPWWTAARKADEQALSQLLE------DRDVDAVDENGRTALLFVAGLGSDKCVRLLAEA 98 Query: 180 GASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTV 239 GA + R G L AA E+V L+E GADI +D G T Sbjct: 99 GADLDHRDMRG------------GLTALHMAAGYVRPEVVEALVELGADIEVEDERGLTA 146 Query: 240 LHIL 243 L + Sbjct: 147 LELA 150 Score = 55.5 bits (132), Expect = 9e-08, Method: Composition-based stats. Identities = 24/102 (23%), Positives = 44/102 (43%), Gaps = 7/102 (6%) Query: 66 RESWAQSRDEQNLLQQKRIWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMG-ETALH 124 ++ +Q +++++ + LL A + ++LL G ++ + G TALH Sbjct: 57 EQALSQLLEDRDVDAVDENGRTALLFVAGLGS-DKCVRLLAEAGADLDHRDMRGGLTALH 115 Query: 125 IAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVI 166 +AA Y E L+E ++ E G TAL +A Sbjct: 116 MAAGYVRPEVVEALVELGADIEV-----EDERGLTALELARE 152 Score = 37.0 bits (84), Expect = 0.035, Method: Composition-based stats. Identities = 22/103 (21%), Positives = 37/103 (35%), Gaps = 10/103 (9%) Query: 204 EHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYD 263 E P AA E+ + L+E D+ A D G T L + + L + Sbjct: 45 ETPWWTAARKADEQALSQLLEDR-DVDAVDENGRTALLFVAGLGSDKCVR------LLAE 97 Query: 264 GGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKRKHIQ 306 G L ++ GLT +A + + L++ I+ Sbjct: 98 AGADLDHRDM---RGGLTALHMAAGYVRPEVVEALVELGADIE 137 >2KXP-C nrPDB Length = 118 Score = 69.0 bits (167), Expect = 8e-12, Method: Composition-based stats. Identities = 22/97 (22%), Positives = 41/97 (42%), Gaps = 6/97 (6%) Query: 86 ESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPEL 145 + + A K ++ + + +G +V++ G LH AA LE L+ ++ Sbjct: 3 DKEFMWALKNGDLDEVKDYV-AKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADI 61 Query: 146 VFEPMTSELYEGQTALHIAVINQNVNLVRALLARGAS 182 + T L AV +V+ V+ LL++GA Sbjct: 62 -----NAPDKHHITPLLSAVYEGHVSCVKLLLSKGAD 93 Score = 64.7 bits (156), Expect = 1e-10, Method: Composition-based stats. Identities = 25/120 (20%), Positives = 41/120 (34%), Gaps = 18/120 (15%) Query: 123 LHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGAS 182 A +L+ + ++ L G+ LH A + ++ LL +GA Sbjct: 6 FMWALKNGDLDEVKDYVAKGEDV-----NRTLEGGRKPLHYAADCGQLEILEFLLLKGAD 60 Query: 183 VSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHI 242 ++A + PL A G V+LL+ GAD + G T L Sbjct: 61 INAPDKHHI-------------TPLLSAVYEGHVSCVKLLLSKGADKTVKGPDGLTALEA 107 Score = 62.8 bits (151), Expect = 5e-10, Method: Composition-based stats. Identities = 32/122 (26%), Positives = 48/122 (39%), Gaps = 23/122 (18%) Query: 162 HIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRL 221 A+ N +++ V+ +A+G V+ G G PL +AA G EI+ Sbjct: 7 MWALKNGDLDEVKDYVAKGEDVNRTLEG-------------GRKPLHYAADCGQLEILEF 53 Query: 222 LIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGLT 281 L+ GADI A D T L + + + + LLLS + V GLT Sbjct: 54 LLLKGADINAPDKHHITPLLSAVYEGHVSCV----KLLLSKGAD------KTVKGPDGLT 103 Query: 282 PF 283 Sbjct: 104 AL 105 Score = 42.8 bits (99), Expect = 5e-04, Method: Composition-based stats. Identities = 22/113 (19%), Positives = 38/113 (33%), Gaps = 11/113 (9%) Query: 209 FAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHL 268 +A G + V+ + G D+ G LH ++ LL + Sbjct: 8 WALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQ----LEILEFLLLKGADIN- 62 Query: 269 KSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKRKHIQWTYGPLTSTLYDLTE 321 P+ +TP A EG++ + L+ K GP T + T+ Sbjct: 63 -----APDKHHITPLLSAVYEGHVSCVKLLLSKGADKTVK-GPDGLTALEATD 109 Score = 31.6 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 16/37 (43%), Positives = 21/37 (56%), Gaps = 1/37 (2%) Query: 87 SPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETAL 123 +PLL A E +V +KLL +G + KG G TAL Sbjct: 70 TPLLSAVYEGHVSC-VKLLLSKGADKTVKGPDGLTAL 105 >5DND-A nrPDB Length = 588 Score = 67.4 bits (163), Expect = 2e-11, Method: Composition-based stats. Identities = 32/168 (19%), Positives = 61/168 (36%), Gaps = 18/168 (10%) Query: 93 AKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTS 152 A ++AL + L G ++ K + G+T LH+AA +L+ ++ + Sbjct: 430 AHAGELEAL-QALMELGSDLRLKDSNGQTLLHVAARNGRDGVVTMLLHRGMDV-----NA 483 Query: 153 ELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAAC 212 +G + L +AV ++ +R L GA +S + + + Sbjct: 484 RDRDGLSPLLLAVQGRHRECIRLLRKAGACLSPQD---LKDAGTELCRLASRADMEGLQA 540 Query: 213 VGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLL 260 G GAD++ G + L + N+ + NL L Sbjct: 541 WGQ---------AGADLQQPGYDGRSALCVAEAAGNQEVLALLRNLAL 579 Score = 54.3 bits (129), Expect = 2e-07, Method: Composition-based stats. Identities = 28/146 (19%), Positives = 56/146 (38%), Gaps = 18/146 (12%) Query: 77 NLLQQKRIWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAM 136 +L + ++ L +AA+ ++ +L G +V+ + G + L +A + E Sbjct: 447 DLRLKDSNGQTLLHVAARNGR-DGVVTMLLHRGMDVNARDRDGLSPLLLAVQGRHRECIR 505 Query: 137 VLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRP 196 +L +A L +L + T L ++ ++A GA + Sbjct: 506 LLRKAGACLSP----QDLKDAGTELCRLASRADMEGLQAWGQAGADLQQPG--------- 552 Query: 197 HNLIYYGEHPLSFAACVGSEEIVRLL 222 Y G L A G++E++ LL Sbjct: 553 ----YDGRSALCVAEAAGNQEVLALL 574 Score = 47.0 bits (110), Expect = 3e-05, Method: Composition-based stats. Identities = 23/98 (23%), Positives = 40/98 (40%), Gaps = 11/98 (11%) Query: 207 LSFA-ACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGG 265 L+ A A G E ++ L+E G+D+R +DS G T+LH+ + + + + Sbjct: 425 LALALAHAGELEALQALMELGSDLRLKDSNGQTLLHVAARNGRDGVVTMLLHRGMDVNAR 484 Query: 266 DHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKRK 303 D GL+P LA + + L + Sbjct: 485 DR----------DGLSPLLLAVQGRHRECIRLLRKAGA 512 >4BSZ-B nrPDB Length = 202 Score = 61.3 bits (147), Expect = 2e-09, Method: Composition-based stats. Identities = 29/146 (19%), Positives = 56/146 (38%), Gaps = 23/146 (15%) Query: 89 LLLAAKENNVQALIKLLK----FEGCEVHQKGAMGETALHIAALYDNLEAAMVLME---- 140 ++L A+ ++ +L + E ++ TALH+AA ++E ++E Sbjct: 18 IILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETVSR 77 Query: 141 -AAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALL-ARGASVSARATGSVFHYRPHN 198 + E + + G TALH A +N +++V+ L A R Sbjct: 78 ANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNK---------- 127 Query: 199 LIYYGEHPLSFAACVGSEEIVRLLIE 224 +G + A G EE+ ++ Sbjct: 128 ---FGHDAIFEAENSGKEEVETYFLK 150 Score = 37.8 bits (86), Expect = 0.017, Method: Composition-based stats. Identities = 20/107 (18%), Positives = 33/107 (30%), Gaps = 19/107 (17%) Query: 205 HPLSFAACVGSEEIVRLLIEH----------GADIRAQDSLGNTVLHILILQPNKTFACQ 254 L AA G E VR ++E A + + GNT LH L Sbjct: 54 TALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKL 113 Query: 255 MYNLLLSYDGGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQK 301 + + ++ + N G A G + + ++K Sbjct: 114 LCD---------EYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKK 151 Score = 37.4 bits (85), Expect = 0.025, Method: Composition-based stats. Identities = 13/76 (17%), Positives = 28/76 (36%), Gaps = 3/76 (3%) Query: 238 TVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQH 297 T LH+ + + + + + LK+ N G T A + G + + + Sbjct: 54 TALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKL 113 Query: 298 LMQKRK---HIQWTYG 310 L + + I+ +G Sbjct: 114 LCDEYEADPFIRNKFG 129 >5U0K-A nrPDB Length = 141 Score = 59.0 bits (141), Expect = 9e-09, Method: Composition-based stats. Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 5/91 (5%) Query: 89 LLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFE 148 LL AA +V AL + ++ QK TALH+AA ++E L+EA Sbjct: 29 LLFAAYSGDVSALRRFALSA-MDMEQKDYDSRTALHVAAAEGHIEVVKFLIEACK---VN 84 Query: 149 PMTSELYEGQTALHIAVINQNVNLVRALLAR 179 P + + G L AV ++ +V+ L Sbjct: 85 PFAKDRW-GNIPLDDAVQFNHLEVVKLLQDY 114 Score = 48.9 bits (115), Expect = 9e-06, Method: Composition-based stats. Identities = 24/100 (24%), Positives = 39/100 (39%), Gaps = 17/100 (17%) Query: 123 LHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGAS 182 L AA ++ A L M + Y+ +TALH+A ++ +V+ L+ Sbjct: 29 LLFAAYSGDVSALRRF-----ALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEA-CK 82 Query: 183 VSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLL 222 V+ A +G PL A E+V+LL Sbjct: 83 VNPFAKDR-----------WGNIPLDDAVQFNHLEVVKLL 111 Score = 45.1 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 21/88 (23%), Positives = 32/88 (36%), Gaps = 2/88 (2%) Query: 172 LVRALLA-RGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEH-GADI 229 +V L A VSA ++ Y L AA G E+V+ LIE + Sbjct: 26 VVNLLFAAYSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEACKVNP 85 Query: 230 RAQDSLGNTVLHILILQPNKTFACQMYN 257 A+D GN L + + + + Sbjct: 86 FAKDRWGNIPLDDAVQFNHLEVVKLLQD 113 Score = 44.7 bits (104), Expect = 2e-04, Method: Composition-based stats. Identities = 13/63 (20%), Positives = 28/63 (44%) Query: 76 QNLLQQKRIWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAA 135 ++ Q+ + L +AA E +++ + L++ K G L A +++LE Sbjct: 49 MDMEQKDYDSRTALHVAAAEGHIEVVKFLIEACKVNPFAKDRWGNIPLDDAVQFNHLEVV 108 Query: 136 MVL 138 +L Sbjct: 109 KLL 111 Score = 31.6 bits (70), Expect = 1.4, Method: Composition-based stats. Identities = 16/92 (17%), Positives = 28/92 (30%), Gaps = 9/92 (9%) Query: 207 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGD 266 L FAA G +R D+ +D T LH+ + + + Sbjct: 29 LLFAAYSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIE--------- 79 Query: 267 HLKSLELVPNNQGLTPFKLAGVEGNIVMFQHL 298 K + G P A ++ + + L Sbjct: 80 ACKVNPFAKDRWGNIPLDDAVQFNHLEVVKLL 111 >6BPQ-A nrPDB Length = 950 Score = 57.0 bits (136), Expect = 3e-08, Method: Composition-based stats. Identities = 47/235 (20%), Positives = 89/235 (37%), Gaps = 31/235 (13%) Query: 428 ELVSIVGAVIILLVEIPDIFRLGVTRFFGQTILGGPFHVIIVTYAFMVLVTMVMRLTNSD 487 E++ V I+L E+ + G F + + + + S Sbjct: 643 EIILYVLVFILLCDEVRQWYMNGSKYFSDLWNVMDTLAIFYFIAGIVFR----LHSDESS 698 Query: 488 GEVVPMSFAL--VLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFAS 545 + F L ++ +++ + LGP IM+Q+M+ D+ F +L AV ++ F Sbjct: 699 WYSGRVIFCLDYIVFTLRLIHIFTVSRNLGPKIIMLQRMMI-DVFFFLFLFAVWMVAFGV 757 Query: 546 AFYIIFQTED----------------------PDEL-GHFYDYPMALFSTFELFLTIIDG 582 A I + + PD++ G Y++ FS E ++ Sbjct: 758 ARQGILRKNEHRWEWIFRSVIYEPYLAMFGQYPDDIDGTTYNFDHCTFSGNESKPLCVEL 817 Query: 583 PANYDVDLP-FMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQV 636 AN P ++ + + +L++NLL+AM G T V D++W+ Q Sbjct: 818 DANNQPRFPEWITIPLVCIYMLSTNILLVNLLVAMFGYTVGSVQENNDQVWKFQR 872 >6BWF-A nrPDB Length = 954 Score = 55.9 bits (133), Expect = 7e-08, Method: Composition-based stats. Identities = 46/238 (19%), Positives = 87/238 (36%), Gaps = 38/238 (15%) Query: 495 FALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTE 554 ++ + ++ F Q GP+ +MI KM+ ++ +MA+V+L F I Sbjct: 621 LNIIFWYVRLLDFLAVNQQAGPYVMMIGKMV-ANMFYIVVIMALVLLSFGVPRKAILY-- 677 Query: 555 DPDELGHFYDYPMALFSTFELFLTIIDGPA----NYDVDLP-------FMYSITYAAFAI 603 P E + +F + + + D LP ++ A + Sbjct: 678 -PHEEPSWSLAKDIVFHPYWMIFGEVYAYEIDVCANDSTLPTICGPGTWLTPFLQAVYLF 736 Query: 604 IATLLMLNLLIAMMGDTHWRVAHERDELWRAQVVATTVMLERK---------------LP 648 + ++M+NLLIA + + +V + +W+ Q + K L Sbjct: 737 VQYIIMVNLLIAFFNNVYLQVKAISNIVWKYQRYHFIMAYHEKPVLPPPLIILSHIVSLF 796 Query: 649 RCLWPRSGICGREYGLGDRWFLRVEDR---QDLNRQRIRRYAQAFQQQDDLYSEDLEK 703 C+ R G + FL ED+ D Q + Y F ++DD ++ E+ Sbjct: 797 CCVCKRRKKDKTSDG--PKLFLTEEDQKKLHDFEEQCVEMY---FDEKDDKFNSGSEE 849 >5U0J-A nrPDB Length = 140 Score = 54.7 bits (130), Expect = 2e-07, Method: Composition-based stats. Identities = 24/113 (21%), Positives = 46/113 (40%), Gaps = 7/113 (6%) Query: 89 LLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFE 148 LL AA +V AL + ++ Q+ TALH+AA ++E L+EA Sbjct: 28 LLFAAYTGDVSALRRFALSA-MDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACK---VN 83 Query: 149 PMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIY 201 P + + T + A+ + ++ + L V G + + + ++ Sbjct: 84 PFPKDRWN-NTPMDEALHFGHHDVFKILQEY--QVQYTPQGDSDNGKENQTVH 133 Score = 46.6 bits (109), Expect = 4e-05, Method: Composition-based stats. Identities = 16/84 (19%), Positives = 33/84 (39%) Query: 76 QNLLQQKRIWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAA 135 ++ Q+ + L +AA E +V+ + LL+ K T + A + + + Sbjct: 48 MDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVF 107 Query: 136 MVLMEAAPELVFEPMTSELYEGQT 159 +L E + + + E QT Sbjct: 108 KILQEYQVQYTPQGDSDNGKENQT 131 Score = 43.9 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 24/115 (20%), Positives = 40/115 (34%), Gaps = 17/115 (14%) Query: 123 LHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGAS 182 L AA ++ A L M Y+ +TALH+A +V +V+ LL Sbjct: 28 LLFAAYTGDVSALRRF-----ALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLE---- 78 Query: 183 VSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGN 237 A + + P+ A G ++ ++L E+ Q N Sbjct: 79 ----ACKVNPFPKDR----WNNTPMDEALHFGHHDVFKILQEYQVQYTPQGDSDN 125 Score = 41.6 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 21/111 (18%), Positives = 37/111 (33%), Gaps = 5/111 (4%) Query: 175 ALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEH-GADIRAQD 233 A VSA ++ Y L AA G E+V+ L+E + +D Sbjct: 29 LFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKD 88 Query: 234 SLGNTVLHILILQPNKTFACQMYNLLLSY----DGGDHLKSLELVPNNQGL 280 NT + + + + + Y D + ++ + N GL Sbjct: 89 RWNNTPMDEALHFGHHDVFKILQEYQVQYTPQGDSDNGKENQTVHKNLDGL 139 Score = 30.1 bits (66), Expect = 3.4, Method: Composition-based stats. Identities = 23/126 (18%), Positives = 41/126 (32%), Gaps = 22/126 (17%) Query: 207 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGD 266 L FAA G +R D+ +D T LH+ + + + Sbjct: 28 LLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFL----------L 77 Query: 267 HLKSLELVPN-NQGLTPFKLAGVEGNIVMFQHLMQKRKHIQWTYGPLTSTLYDLTEIDSS 325 + P TP A G+ +F+ L + Q Y P + D+ Sbjct: 78 EACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQEY----QVQYTPQGDS-------DNG 126 Query: 326 GDDQSL 331 ++Q++ Sbjct: 127 KENQTV 132 >6DJS-A nrPDB Length = 676 Score = 54.3 bits (129), Expect = 2e-07, Method: Composition-based stats. Identities = 32/156 (20%), Positives = 56/156 (35%), Gaps = 23/156 (14%) Query: 89 LLLAAKENNVQALIKLLK-FEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVF 147 L AA+ N+ + K+L+ + V+ MG+ AL +A ++LE +L++ Sbjct: 48 FLDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLK------- 100 Query: 148 EPMTSELYEGQTALHIAVINQNVNLVRALLARGA------------SVSARATGSVFHYR 195 L AL +A+ V +V A+L + + Sbjct: 101 ---KENLARIGDALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAYDE 157 Query: 196 PHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRA 231 P+ AA E+V +L+ GA I Sbjct: 158 DGTRFSPDITPIILAAHCQKYEVVHMLLMKGARIER 193 Score = 47.8 bits (112), Expect = 2e-05, Method: Composition-based stats. Identities = 36/184 (19%), Positives = 59/184 (32%), Gaps = 39/184 (21%) Query: 123 LHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGAS 182 AA Y N+ ++E + L + Y GQ AL +AV N+++ + LL + Sbjct: 48 FLDAAEYGNIPVVRKMLEESKTLN---VNCVDYMGQNALQLAVGNEHLEVTELLLKK--- 101 Query: 183 VSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHI 242 NL G+ L A G IV ++ H A L + Sbjct: 102 --------------ENLARIGDA-LLLAISKGYVRIVEAILNHPG-FAASKRLTLSP--- 142 Query: 243 LILQPNKTFACQMYNLLLSYDGGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKR 302 Q + Y+ + + +TP LA + L+ K Sbjct: 143 -CEQELQDDDFYAYDE-------------DGTRFSPDITPIILAAHCQKYEVVHMLLMKG 188 Query: 303 KHIQ 306 I+ Sbjct: 189 ARIE 192 >5UQE-A nrPDB Length = 520 Score = 54.0 bits (128), Expect = 2e-07, Method: Composition-based stats. Identities = 22/91 (24%), Positives = 39/91 (42%), Gaps = 5/91 (5%) Query: 89 LLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFE 148 LL AA +V AL + ++ Q+ TALH+AA ++E L+EA Sbjct: 421 LLFAAYTGDVSALRRFALSA-MDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACK---VN 476 Query: 149 PMTSELYEGQTALHIAVINQNVNLVRALLAR 179 P + + T + A+ + ++ + L Sbjct: 477 PFPKDRWN-NTPMDEALHFGHHDVFKILQEY 506 Score = 43.9 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 24/115 (20%), Positives = 40/115 (34%), Gaps = 17/115 (14%) Query: 123 LHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGAS 182 L AA ++ A L M Y+ +TALH+A +V +V+ LL Sbjct: 421 LLFAAYTGDVSALRRF-----ALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLE---- 471 Query: 183 VSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGN 237 A + + P+ A G ++ ++L E+ Q N Sbjct: 472 ----ACKVNPFPKDR----WNNTPMDEALHFGHHDVFKILQEYQVQYTPQGDSDN 518 Score = 42.8 bits (99), Expect = 6e-04, Method: Composition-based stats. Identities = 13/78 (16%), Positives = 30/78 (38%) Query: 76 QNLLQQKRIWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAA 135 ++ Q+ + L +AA E +V+ + LL+ K T + A + + + Sbjct: 441 MDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVF 500 Query: 136 MVLMEAAPELVFEPMTSE 153 +L E + + + Sbjct: 501 KILQEYQVQYTPQGDSDN 518 Score = 40.9 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 17/89 (19%), Positives = 29/89 (32%), Gaps = 1/89 (1%) Query: 175 ALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEH-GADIRAQD 233 A VSA ++ Y L AA G E+V+ L+E + +D Sbjct: 422 LFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKD 481 Query: 234 SLGNTVLHILILQPNKTFACQMYNLLLSY 262 NT + + + + + Y Sbjct: 482 RWNNTPMDEALHFGHHDVFKILQEYQVQY 510 Score = 30.1 bits (66), Expect = 3.6, Method: Composition-based stats. Identities = 18/97 (18%), Positives = 31/97 (31%), Gaps = 11/97 (11%) Query: 207 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGD 266 L FAA G +R D+ +D T LH+ + + + Sbjct: 421 LLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFL----------L 470 Query: 267 HLKSLELVPN-NQGLTPFKLAGVEGNIVMFQHLMQKR 302 + P TP A G+ +F+ L + + Sbjct: 471 EACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQEYQ 507 >3LVQ-E nrPDB Length = 497 Score = 52.8 bits (125), Expect = 5e-07, Method: Composition-based stats. Identities = 28/99 (28%), Positives = 40/99 (40%), Gaps = 7/99 (7%) Query: 89 LLLAAKENNVQAL--IKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 L LA K N +L + + G + K A G TALH AALY+ + +L++ + Sbjct: 175 LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVG 234 Query: 147 FEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSA 185 G+TAL IA + L A A Sbjct: 235 T-----VNEAGETALDIARKKHHKECEELLEQAQAGTFA 268 Score = 42.4 bits (98), Expect = 8e-04, Method: Composition-based stats. Identities = 20/93 (21%), Positives = 37/93 (39%), Gaps = 16/93 (17%) Query: 161 LHIA---VINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEE 217 LH+A ++ LV ++ G + A+A G L +AA + Sbjct: 175 LHLAVKVANQASLPLVDFIIQNGGHLDAKAAD-------------GNTALHYAALYNQPD 221 Query: 218 IVRLLIEHGADIRAQDSLGNTVLHILILQPNKT 250 ++LL++ A + + G T L I + +K Sbjct: 222 CLKLLLKGRALVGTVNEAGETALDIARKKHHKE 254 Score = 40.5 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 24/108 (22%), Positives = 37/108 (34%), Gaps = 21/108 (19%) Query: 123 LHIA---ALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLAR 179 LH+A A +L +++ L + G TALH A + + ++ LL Sbjct: 175 LHLAVKVANQASLPLVDFIIQNGGHLDAKAAD-----GNTALHYAALYNQPDCLKLLLKG 229 Query: 180 GASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGA 227 A V + GE L A +E LL + A Sbjct: 230 RALV-------------GTVNEAGETALDIARKKHHKECEELLEQAQA 264 Score = 34.3 bits (77), Expect = 0.20, Method: Composition-based stats. Identities = 22/71 (30%), Positives = 25/71 (35%), Gaps = 2/71 (2%) Query: 85 WESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPE 144 + L AA N L LLK V GETAL IA + E L+E A Sbjct: 207 GNTALHYAALYNQPDCLKLLLKGR-ALVGTVNEAGETALDIARKKHHKE-CEELLEQAQA 264 Query: 145 LVFEPMTSELY 155 F Y Sbjct: 265 GTFAFPLHVDY 275 >2B0O-E nrPDB Length = 301 Score = 52.8 bits (125), Expect = 5e-07, Method: Composition-based stats. Identities = 28/99 (28%), Positives = 40/99 (40%), Gaps = 7/99 (7%) Query: 89 LLLAAKENNVQAL--IKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELV 146 L LA K N +L + + G + K A G TALH AALY+ + +L++ + Sbjct: 194 LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVG 253 Query: 147 FEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSA 185 G+TAL IA + L A A Sbjct: 254 T-----VNEAGETALDIARKKHHKECEELLEQAQAGTFA 287 Score = 42.4 bits (98), Expect = 8e-04, Method: Composition-based stats. Identities = 20/93 (21%), Positives = 37/93 (39%), Gaps = 16/93 (17%) Query: 161 LHIA---VINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEE 217 LH+A ++ LV ++ G + A+A G L +AA + Sbjct: 194 LHLAVKVANQASLPLVDFIIQNGGHLDAKAAD-------------GNTALHYAALYNQPD 240 Query: 218 IVRLLIEHGADIRAQDSLGNTVLHILILQPNKT 250 ++LL++ A + + G T L I + +K Sbjct: 241 CLKLLLKGRALVGTVNEAGETALDIARKKHHKE 273 Score = 40.5 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 24/108 (22%), Positives = 37/108 (34%), Gaps = 21/108 (19%) Query: 123 LHIA---ALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLAR 179 LH+A A +L +++ L + G TALH A + + ++ LL Sbjct: 194 LHLAVKVANQASLPLVDFIIQNGGHLDAKAAD-----GNTALHYAALYNQPDCLKLLLKG 248 Query: 180 GASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGA 227 A V + GE L A +E LL + A Sbjct: 249 RALV-------------GTVNEAGETALDIARKKHHKECEELLEQAQA 283 Score = 34.3 bits (77), Expect = 0.20, Method: Composition-based stats. Identities = 22/71 (30%), Positives = 25/71 (35%), Gaps = 2/71 (2%) Query: 85 WESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPE 144 + L AA N L LLK V GETAL IA + E L+E A Sbjct: 226 GNTALHYAALYNQPDCLKLLLKGR-ALVGTVNEAGETALDIARKKHHKE-CEELLEQAQA 283 Query: 145 LVFEPMTSELY 155 F Y Sbjct: 284 GTFAFPLHVDY 294 >1D9S-A nrPDB Length = 136 Score = 52.4 bits (124), Expect = 7e-07, Method: Composition-based stats. Identities = 25/141 (17%), Positives = 51/141 (36%), Gaps = 18/141 (12%) Query: 112 VHQKGAMGETALHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVN 171 +H G + L AA +E L+EA + + G+ + + ++ + Sbjct: 5 IHMLGGSSDAGLATAAARGQVETVRQLLEAGAD-----PNALNRFGRRPIQV-MMMGSAQ 58 Query: 172 LVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRA 231 + LL GA + ++ P+ AA G + + +L GA + Sbjct: 59 VAELLLLHGAEPNCADPATLTR------------PVHDAAREGFLDTLVVLHRAGARLDV 106 Query: 232 QDSLGNTVLHILILQPNKTFA 252 D+ G + + Q ++ A Sbjct: 107 CDAWGRLPVDLAEEQGHRDIA 127 Score = 46.6 bits (109), Expect = 4e-05, Method: Composition-based stats. Identities = 26/112 (23%), Positives = 42/112 (37%), Gaps = 12/112 (10%) Query: 207 LSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGD 266 L+ AA G E VR L+E GAD A + G + ++++ Q+ LLL + Sbjct: 16 LATAAARGQVETVRQLLEAGADPNALNRFGRRPIQVMMMGS-----AQVAELLLLHGAEP 70 Query: 267 HLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKRKHIQ--WTYGPLTSTL 316 + + P A EG + L + + +G L L Sbjct: 71 NCADPATLTR-----PVHDAAREGFLDTLVVLHRAGARLDVCDAWGRLPVDL 117 Score = 37.4 bits (85), Expect = 0.021, Method: Composition-based stats. Identities = 12/51 (23%), Positives = 22/51 (43%), Gaps = 1/51 (1%) Query: 88 PLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVL 138 P+ AA+E + L+ L + G + A G + +A + + A L Sbjct: 81 PVHDAAREGFLDTLVVLHRA-GARLDVCDAWGRLPVDLAEEQGHRDIARYL 130 >5Z1W-A nrPDB Length = 566 Score = 49.3 bits (116), Expect = 7e-06, Method: Composition-based stats. Identities = 46/318 (14%), Positives = 107/318 (33%), Gaps = 45/318 (14%) Query: 337 TTKKREARQILDQTPVKELVSLKWKRYGRPYFCVLGAIYVLYIICFTMCCVYRPLKPRIT 396 +RQ ++ L W G + ++Y I F C+ R + Sbjct: 208 YLDLPGSRQ-ASAEALQGLQEGLWLDRGTRVVFIDFSVYNANINLF---CILRLVVEFPA 263 Query: 397 NRTNPRDNTLLQQKLLQEAYVTPKDDLRLVGELVSIVGAVIILLVEIPDIFRLGVTRFFG 456 + KL++ YV D + E+V V ++ EI +I + Sbjct: 264 TGGTIPSWQIRTVKLIR--YVNNWDFFIVGCEVVFCVFIFYYVVEEILEIHLHRLR---- 317 Query: 457 QTILGGPFHVIIVTYAFMVLVTMVMRLTNSDGEVVPM----------------------- 493 L ++++ + + +V + + + M Sbjct: 318 --YLSSVWNILDLVVILLSIVAVGFHIFRTLEVNRLMGKLLQQPDTYADFEFLAFWQTQY 375 Query: 494 ----SFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYI 549 + L W + + + + + + + D++ F + +V +A Y+ Sbjct: 376 NNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCA-KDILGFAIMFFIVFFAYAQLGYL 434 Query: 550 IFQTEDPDELGHFYDYPMALFSTFELFLTIIDGPANYDVDLPFMYSITYAAFAIIATLLM 609 +F T+ + F + +F+ F + L D A + + + + + + ++ Sbjct: 435 LFGTQVEN----FSTFVKCIFTQFRIILGDFDYNAIDNAN-RILGPVYFVTYVFFVFFVL 489 Query: 610 LNLLIAMMGDTHWRVAHE 627 LN+ +A++ DT+ V E Sbjct: 490 LNMFLAIINDTYSEVKEE 507 >6DU8-A nrPDB Length = 805 Score = 48.9 bits (115), Expect = 7e-06, Method: Composition-based stats. Identities = 57/352 (16%), Positives = 120/352 (34%), Gaps = 39/352 (11%) Query: 303 KHIQWTYGPLTSTLYDLTEID-----SSGDDQSLLELIVTTKKREARQILDQTPVKELVS 357 K Q +GP T + D S + + ++ L Sbjct: 231 KEEQLPFGPFNGTAWTYHSQDELGGFSHWGRLTSYSGGGYYLDLPGSRQGSAEALRALQE 290 Query: 358 LKWKRYGRPYFCVLGAIYVLYIICFTMCCVYRPLKPRITNRTNPRDNTLLQQKLLQEAYV 417 W G + ++Y I F CV R + + KL++ YV Sbjct: 291 GLWLDRGTRVVFIDFSVYNANINLF---CVLRLVVEFPATGGAIPSWQIRTVKLIR--YV 345 Query: 418 TPKDDLRLVGELVSIVGAVIILLVEIPD--IFRLGVTRFFG---------QTILGGPFHV 466 + D + E++ V ++ EI + I RL +I+ FH+ Sbjct: 346 SNWDFFIVGCEVIFCVFIFYYVVEEILELHIHRLRYLSSIWNILDLVVILLSIVAVGFHI 405 Query: 467 IIVTYAFMVLVTMVMRLTNSDGEVVPMSF-----------ALVLGWCNVMYFARGFQMLG 515 T L+ +++ N+ + ++F L W + + + + Sbjct: 406 -FRTLEVNRLMGKLLQQPNTYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMT 464 Query: 516 PFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPDELGHFYDYPMALFSTFEL 575 + + + D++ F + +V +A Y++F T+ + F + +F+ F + Sbjct: 465 QLSSTLARCA-KDILGFAVMFFIVFFAYAQLGYLLFGTQVEN----FSTFIKCIFTQFRI 519 Query: 576 FLTIIDGPANYDVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHE 627 L D A + + + + + ++LN+ +A++ DT+ V E Sbjct: 520 ILGDFDYNAIDNAN-RILGPAYFVTYVFFVFFVLLNMFLAIINDTYSEVKEE 570 >2A5E-A nrPDB Length = 156 Score = 48.2 bits (113), Expect = 1e-05, Method: Composition-based stats. Identities = 22/130 (16%), Positives = 46/130 (35%), Gaps = 18/130 (13%) Query: 123 LHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGAS 182 L AA +E L+EA + G+ + + ++ + + LL GA Sbjct: 16 LATAAARGRVEEVRALLEAGA-----LPNAPNSYGRRPIQV-MMMGSARVAELLLLHGAE 69 Query: 183 VSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHI 242 + ++ P+ AA G + + +L GA + +D+ G + + Sbjct: 70 PNCADPATLTR------------PVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDL 117 Query: 243 LILQPNKTFA 252 ++ A Sbjct: 118 AEELGHRDVA 127 Score = 44.7 bits (104), Expect = 1e-04, Method: Composition-based stats. Identities = 30/145 (20%), Positives = 50/145 (34%), Gaps = 15/145 (10%) Query: 206 PLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGG 265 L+ AA G E VR L+E GA A +S G + ++++ ++ LLL + Sbjct: 15 WLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGS-----ARVAELLLLHGAE 69 Query: 266 DHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHLMQKRK--HIQWTYGPLTSTLYDLTEID 323 + + P A EG + L + ++ +G L DL E Sbjct: 70 PNCADPATLTR-----PVHDAAREGFLDTLVVLHRAGARLDVRDAWGRL---PVDLAEEL 121 Query: 324 SSGDDQSLLELIVTTKKREARQILD 348 D L + +D Sbjct: 122 GHRDVARYLRAAAGGTRGSNHARID 146 Score = 34.3 bits (77), Expect = 0.18, Method: Composition-based stats. Identities = 12/51 (23%), Positives = 23/51 (45%), Gaps = 1/51 (1%) Query: 88 PLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVL 138 P+ AA+E + L+ L + G + + A G + +A + + A L Sbjct: 81 PVHDAAREGFLDTLVVLHRA-GARLDVRDAWGRLPVDLAEELGHRDVARYL 130 >1DCQ-A nrPDB Length = 278 Score = 47.0 bits (110), Expect = 3e-05, Method: Composition-based stats. Identities = 29/191 (15%), Positives = 64/191 (33%), Gaps = 33/191 (17%) Query: 77 NLLQQKRIWESPLLLA--AKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEA 134 +++ +K + + A++ + KL V + G + A D ++ Sbjct: 102 DMIARKDYITAKYMERRYARKKHADTAAKLHSLCEA-VKTRDIFGL----LQAYADGVDL 156 Query: 135 AMVLMEAAPELVFEPMTSELYEGQTALHIAV---INQNVNLVRALLARGASVSARATGSV 191 + P+ + +TALH+AV ++++V L+ ++ + Sbjct: 157 TEKI----------PLANGHEPDETALHLAVRSVDRTSLHIVDFLVQNSGNLDKQTGK-- 204 Query: 192 FHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTF 251 G L + + E ++LL+ A I + G T L I ++ Sbjct: 205 -----------GSTALHYCCLTDNAECLKLLLRGKASIEIANESGETPLDIAKRLKHEHC 253 Query: 252 ACQMYNLLLSY 262 + L Sbjct: 254 EELLTQALSGR 264 Score = 41.2 bits (95), Expect = 0.002, Method: Composition-based stats. Identities = 28/135 (20%), Positives = 44/135 (32%), Gaps = 19/135 (14%) Query: 161 LHIAVIN-QNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAA---CVGSE 216 LH + ++ L A V + + + E L A S Sbjct: 131 LHSLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPD-----ETALHLAVRSVDRTSL 185 Query: 217 EIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLELVPN 276 IV L+++ ++ Q G+T LH L N LLL K+ + N Sbjct: 186 HIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAE----CLKLLL------RGKASIEIAN 235 Query: 277 NQGLTPFKLAGVEGN 291 G TP +A + Sbjct: 236 ESGETPLDIAKRLKH 250 >5OEO-C nrPDB Length = 73 Score = 45.9 bits (107), Expect = 7e-05, Method: Composition-based stats. Identities = 18/53 (33%), Positives = 28/53 (52%), Gaps = 10/53 (18%) Query: 702 EKDSGEKLEMARPFGA--------YLSFPTPSVSRSTSRSSTN--WDRLRQGA 744 ++D E +P GA L+ PT S+SR+ S+SS++ W+ LRQ Sbjct: 4 KEDDQEHPSEKQPSGAESGTLARASLALPTSSLSRTASQSSSHRGWEILRQNT 56 >5UIL-A nrPDB Length = 405 Score = 45.5 bits (106), Expect = 1e-04, Method: Composition-based stats. Identities = 22/99 (22%), Positives = 45/99 (45%), Gaps = 9/99 (9%) Query: 157 GQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSE 216 G + + +A + N+ L++ L+++GA+++ R + +Y+ ++ L G Sbjct: 311 GWSPVIVAAYHGNIELIKWLVSKGANINDRN-----YKGTTVAMYFKDYMLKSGDYSG-- 363 Query: 217 EIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQM 255 +++LI+ G D+ D TV L NK M Sbjct: 364 --LKMLIDLGLDLTLTDYKDYTVFDYLEKSGNKNLLQYM 400 Score = 38.5 bits (88), Expect = 0.011, Method: Composition-based stats. Identities = 24/110 (21%), Positives = 47/110 (42%), Gaps = 10/110 (9%) Query: 73 RDEQNLLQQKRIWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALY--- 129 R + L ++ SP+++AA N++ LIK L +G ++ + G T Y Sbjct: 299 RAKSILFEKNIYGWSPVIVAAYHGNIE-LIKWLVSKGANINDRNYKGTTVAMYFKDYMLK 357 Query: 130 -DNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLA 178 + +L++ +L T Y+ T + N NL++ ++A Sbjct: 358 SGDYSGLKMLIDLGLDL-----TLTDYKDYTVFDYLEKSGNKNLLQYMMA 402 Score = 32.4 bits (72), Expect = 0.79, Method: Composition-based stats. Identities = 14/38 (36%), Positives = 23/38 (60%) Query: 202 YGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTV 239 YG P+ AA G+ E+++ L+ GA+I ++ G TV Sbjct: 310 YGWSPVIVAAYHGNIELIKWLVSKGANINDRNYKGTTV 347 >5T4D-A nrPDB Length = 510 Score = 45.1 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 25/127 (19%), Positives = 54/127 (42%), Gaps = 6/127 (4%) Query: 501 WCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPDELG 560 W + F + + + + + DL F + ++ L +A Y++F T D+ Sbjct: 378 WIKLFKFINFNRTMSQLSTTMSRCA-KDLFGFAIMFFIIFLAYAQLAYLVFGT-QVDDFS 435 Query: 561 HFYDYPMALFSTFELFLTIIDGPANYDVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDT 620 F + +F+ F + L I+ A + + I + F ++LN+ +A++ DT Sbjct: 436 TFQE---CIFTQFRIILGDINF-AEIEEANRVLGPIYFTTFVFFMFFILLNMFLAIINDT 491 Query: 621 HWRVAHE 627 + V + Sbjct: 492 YSEVKSD 498 >5MKE-A nrPDB Length = 968 Score = 44.7 bits (104), Expect = 1e-04, Method: Composition-based stats. Identities = 25/127 (19%), Positives = 54/127 (42%), Gaps = 6/127 (4%) Query: 501 WCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPDELG 560 W + F + + + + + DL F + ++ L +A Y++F T D+ Sbjct: 570 WIKLFKFINFNRTMSQLSTTMSRCA-KDLFGFAIMFFIIFLAYAQLAYLVFGT-QVDDFS 627 Query: 561 HFYDYPMALFSTFELFLTIIDGPANYDVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDT 620 F + +F+ F + L I+ A + + I + F ++LN+ +A++ DT Sbjct: 628 TFQE---CIFTQFRIILGDINF-AEIEEANRVLGPIYFTTFVFFMFFILLNMFLAIINDT 683 Query: 621 HWRVAHE 627 + V + Sbjct: 684 YSEVKSD 690 >5WPT-A nrPDB Length = 592 Score = 44.7 bits (104), Expect = 2e-04, Method: Composition-based stats. Identities = 48/253 (18%), Positives = 99/253 (39%), Gaps = 36/253 (14%) Query: 405 TLLQQKLLQEAYVTPKDDLRLVGELVSIVGAVI------------ILLVEIPDIF---RL 449 T +Q+ + RL+ ++V I+ + LL +F R Sbjct: 279 THIQECKHPSVSRHGDNSFRLLFDVVVILTCSLSFLLCARSLLRGFLLQNEFVVFMWRRR 338 Query: 450 GVTRFFGQ--TILGGPFHVIIVTYAFMVLVTMVMR-------LTNSDGEVVPMSFALVLG 500 G + + G + +++VT + + VM+ L + D + + + +L Sbjct: 339 GREISLWERLEFVNGWY-ILLVTSDVLTISGTVMKIGIEAKNLASYDVCSILLGTSTLLV 397 Query: 501 WCNVMYFARGFQMLGPFTIMIQ--KMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPDE 558 W V+ + F + I+I ++ +MRFC +AV+ LG+ +I+ + Sbjct: 398 WVGVIRYLTFFHK---YNILIATLRVALPSVMRFCCCVAVIYLGYCFCGWIVLGPYHV-K 453 Query: 559 LGHFYDYPMALFSTF---ELFLTIIDGPANY-DVDLPFMYSITYA-AFAIIATLLMLNLL 613 LFS ++F+T A L +++S Y +F + ++L+L Sbjct: 454 FRSLSMVSECLFSLINGDDMFVTFAAMQAQQGHSSLVWLFSQLYLYSFISLFIYMVLSLF 513 Query: 614 IAMMGDTHWRVAH 626 IA++ + + H Sbjct: 514 IALITGAYDTIKH 526 >6E7Z-A nrPDB Length = 580 Score = 42.8 bits (99), Expect = 6e-04, Method: Composition-based stats. Identities = 43/245 (17%), Positives = 95/245 (38%), Gaps = 36/245 (14%) Query: 413 QEAYVTPKDDLRLVGELVSIVGAVIILLVEIPDIFR---------------LGVTRFFGQ 457 + + RL+ ++V I+ + L+ + R G + Sbjct: 287 PSVFQHGDNSFRLLFDVVVILTCSLSFLLCARSLLRGFLLQNEFVGFMWRQRGRVISLWE 346 Query: 458 --TILGGPFHVIIVTYAFMVLVTMVMR-------LTNSDGEVVPMSFALVLGWCNVMYFA 508 + G + +++VT + + +M+ L + D + + + +L W V+ + Sbjct: 347 RLEFVNGWY-ILLVTSDVLTISGTIMKIGIEAKNLASYDVCSILLGTSTLLVWVGVIRYL 405 Query: 509 RGFQMLGPFTIMIQ--KMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPDELGHFYDYP 566 F + I+I ++ +MRFC +AV+ LG+ +I+ + Sbjct: 406 TFFHN---YNILIATLRVALPSVMRFCCCVAVIYLGYCFCGWIVLGPYHV-KFRSLSMVS 461 Query: 567 MALFSTF---ELFLTIIDGPANY-DVDLPFMYSITYA-AFAIIATLLMLNLLIAMMGDTH 621 LFS ++F+T A L +++S Y +F + ++L+L IA++ + Sbjct: 462 ECLFSLINGDDMFVTFAAMQAQQGRSSLVWLFSQLYLYSFISLFIYMVLSLFIALITGAY 521 Query: 622 WRVAH 626 + H Sbjct: 522 DTIKH 526 >6D1W-A nrPDB Length = 740 Score = 42.4 bits (98), Expect = 7e-04, Method: Composition-based stats. Identities = 25/127 (19%), Positives = 54/127 (42%), Gaps = 6/127 (4%) Query: 501 WCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPDELG 560 W + F + + + + + DL F + ++ L +A Y++F T D+ Sbjct: 518 WIKLFKFINFNRTMSQLSTTMSRCA-KDLFGFAIMPFIIFLAYAQLAYLVFGT-QVDDFS 575 Query: 561 HFYDYPMALFSTFELFLTIIDGPANYDVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDT 620 F + +F+ F + L I+ A + + I + F ++LN+ +A++ DT Sbjct: 576 TFQE---CIFTQFRIILGDINF-AEIEEANRVLGPIYFTTFVFFMFFILLNMFLAIINDT 631 Query: 621 HWRVAHE 627 + V + Sbjct: 632 YSEVKSD 638 >6AYG-A nrPDB Length = 558 Score = 40.9 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 29/157 (18%), Positives = 63/157 (40%), Gaps = 4/157 (2%) Query: 472 AFMVLVTMVMRLTNSDGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMR 531 + + + LT+ D + + + +L W V+ + F + +Q +++R Sbjct: 361 SILKMEIQAKSLTSYDVCSILLGTSTMLVWLGVIRYLGFFAKYNLLILTLQAA-LPNVIR 419 Query: 532 FCWLMAVVILGFASAFYIIFQTEDPDELGHFYDYPMALFSTF-ELFLTIIDGPANYDVDL 590 FC A++ LG+ +I+ D+ LFS + L Sbjct: 420 FCCCAAMIYLGYCFCGWIVLGPYH-DKFRSLNMVSECLFSLINGDDMFATFAKMQQKSYL 478 Query: 591 PFMYSITYA-AFAIIATLLMLNLLIAMMGDTHWRVAH 626 +++S Y +F + ++L+L IA++ DT+ + Sbjct: 479 VWLFSRIYLYSFISLFIYMILSLFIALITDTYETIKQ 515 >4XD0-A nrPDB Length = 417 Score = 39.3 bits (90), Expect = 0.006, Method: Composition-based stats. Identities = 19/99 (19%), Positives = 44/99 (44%), Gaps = 9/99 (9%) Query: 157 GQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSE 216 G + + IA + N++++ L+++G +++ R + +Y+ ++ L G E Sbjct: 324 GWSPIIIAAYHGNMDVIEWLVSKGVNINDRN-----YKGTTVAMYFKDYMLRSGNYTGLE 378 Query: 217 EIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQM 255 ++ L G D+ +D+ G +V + N M Sbjct: 379 NLINL----GLDLFLKDNEGLSVFDYMRKNKNIELFNFM 413 Score = 33.5 bits (75), Expect = 0.38, Method: Composition-based stats. Identities = 20/104 (19%), Positives = 40/104 (38%), Gaps = 10/104 (9%) Query: 73 RDEQNLLQQKRIWESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALY--- 129 + E L ++ + SP+++AA N+ + L+ +G ++ + G T Y Sbjct: 312 KTENILFEKNHLGWSPIIIAAYHGNMDVIEWLV-SKGVNINDRNYKGTTVAMYFKDYMLR 370 Query: 130 -DNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNL 172 N L+ +L + EG + N+N+ L Sbjct: 371 SGNYTGLENLINLGLDLFLK-----DNEGLSVFDYMRKNKNIEL 409 Score = 32.8 bits (73), Expect = 0.61, Method: Composition-based stats. Identities = 23/102 (22%), Positives = 42/102 (41%), Gaps = 14/102 (13%) Query: 201 YYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVL----HILILQPNKTFACQMY 256 + G P+ AA G+ +++ L+ G +I ++ G TV ++ N T + Sbjct: 322 HLGWSPIIIAAYHGNMDVIEWLVSKGVNINDRNYKGTTVAMYFKDYMLRSGNYTGLENLI 381 Query: 257 NLLLSYDGGDHLKSLELVPNNQGLTPFKLAGVEGNIVMFQHL 298 NL L + +N+GL+ F NI +F + Sbjct: 382 NLGLDL----------FLKDNEGLSVFDYMRKNKNIELFNFM 413 >4DXW-A nrPDB Length = 229 Score = 38.2 bits (87), Expect = 0.016, Method: Composition-based stats. Identities = 24/103 (23%), Positives = 45/103 (43%), Gaps = 9/103 (8%) Query: 520 MIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTEDPDELGHFYDYPMALFSTFELF-LT 578 ++++ F L+ F L +A+ I+F +DP G + LF L Sbjct: 129 SVRRVFFVSLLLFIILYI-----YATMGAILFGNDDPSRWGDLGISLITLFQVLTLSSWE 183 Query: 579 IIDGPANYDVDLPFMYSITYAAFAIIATLLMLNLLIAMMGDTH 621 + P ++Y + +F II ++ +LNL+IA++ D Sbjct: 184 TVMLPMQEIYWWSWVY---FFSFIIICSITILNLVIAILVDVV 223 >6BWI-A nrPDB Length = 977 Score = 38.2 bits (87), Expect = 0.016, Method: Composition-based stats. Identities = 13/37 (35%), Positives = 18/37 (48%) Query: 607 LLMLNLLIAMMGDTHWRVAHERDELWRAQVVATTVML 643 +L++NLLIAM T +V D W+AQ Sbjct: 834 ILLVNLLIAMFSYTFGKVQGNSDLYWKAQRYRLIREF 870 >3JB9-c nrPDB Length = 639 Score = 37.0 bits (84), Expect = 0.035, Method: Composition-based stats. Identities = 24/119 (20%), Positives = 45/119 (37%), Gaps = 4/119 (3%) Query: 632 WRAQVVATTVMLERKLPRCLWPRSGICGREYGLGDRWFLRVEDRQDLNRQRIRRYAQAFQ 691 WR + + + P + YG + +E+R +L ++ R Q Sbjct: 175 WRMMKLKRVFDMAQDQ---RRPVEEVALERYGSLKEFDFALEERDELELRKRTRKVQKEV 231 Query: 692 QQDDLYSEDLEKDSGEKLEMARPFGAYLSFPTPSVSRSTSRSSTNWDRLRQGALRKDLQ 750 +LY + + + + Y P PSV++ T S + +RL+ LR L+ Sbjct: 232 PTGELYEKRCADEFKTRKDSGNGATYYKVIPDPSVNKDTPTES-DLNRLKADLLRAQLK 289 >4GX0-A nrPDB Length = 565 Score = 31.2 bits (69), Expect = 1.9, Method: Composition-based stats. Identities = 13/85 (15%), Positives = 36/85 (42%), Gaps = 4/85 (4%) Query: 530 MRFCWLMAVVILGFASAFYIIFQTEDPDELGHFYDYPMALFSTFELFLTIIDGPANYDVD 589 ++ L +L A+ IF+ G Y + ++ T + T+ G ++ D Sbjct: 17 LKVLLLYCAFLLVMLLAYASIFRYLMWHLEGRAYSFMAGIYWTITVMTTLGFGDITFESD 76 Query: 590 LPFMYSITYAAFAIIATLLMLNLLI 614 + +A+ ++ ++ L++++ Sbjct: 77 AGY----LFASIVTVSGVIFLDIIL 97 >2GBW-A nrPDB Length = 454 Score = 30.8 bits (68), Expect = 2.3, Method: Composition-based stats. Identities = 34/192 (17%), Positives = 56/192 (29%), Gaps = 32/192 (16%) Query: 182 SVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGAD------IRAQDSL 235 V A +F L + P ++++ H +D I + Sbjct: 24 DVYALEIERIFSRAWLMLGHESLVPKPGDFITTYMAEDKVILSHQSDGTFRAFINSCSHR 83 Query: 236 GNTVLHILILQPN-KTFACQMYNLLLSYDGGDHLKSLELVPNNQGLTPFKLAGVEGNIVM 294 GN + H N K F C + + DG LE + L KLA + Sbjct: 84 GNQICHA--DSGNAKAFVCNYHGWVFGQDGSLVDVPLESRCYHNSLDKQKLAAKSVRVET 141 Query: 295 FQHLMQKRKHIQWTYGPLTSTLYDLTE-----IDSSGDDQSLLELIVTTKKREARQILDQ 349 ++ I + P +L D +D+ + L Sbjct: 142 YK------GFIFGCHDPEAPSLEDYLGEFRYYLDTIWEGA------------GGGMELLG 183 Query: 350 TPVKELVSLKWK 361 P+K L+ WK Sbjct: 184 PPMKSLLQCNWK 195 >2QHX-A nrPDB Length = 328 Score = 30.1 bits (66), Expect = 3.5, Method: Composition-based stats. Identities = 14/78 (17%), Positives = 23/78 (29%), Gaps = 8/78 (10%) Query: 91 LAAKENNVQALIKLLKFEGCEVHQKGAMGETALHI--------AALYDNLEAAMVLMEAA 142 L A+ N ++ GA G + + AA Y + VL+ A Sbjct: 91 LNARRPNSAITVQADLSNVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNA 150 Query: 143 PELVFEPMTSELYEGQTA 160 P+ +G Sbjct: 151 SSFYPTPLLRNDEDGHEP 168 >2BFA-A nrPDB Length = 288 Score = 30.1 bits (66), Expect = 3.5, Method: Composition-based stats. Identities = 14/78 (17%), Positives = 23/78 (29%), Gaps = 8/78 (10%) Query: 91 LAAKENNVQALIKLLKFEGCEVHQKGAMGETALHI--------AALYDNLEAAMVLMEAA 142 L A+ N ++ GA G + + AA Y + VL+ A Sbjct: 51 LNARRPNSAITVQADLSNVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNA 110 Query: 143 PELVFEPMTSELYEGQTA 160 P+ +G Sbjct: 111 SSFYPTPLLRNDEDGHEP 128 >3CO4-A nrPDB Length = 312 Score = 30.1 bits (66), Expect = 3.7, Method: Composition-based stats. Identities = 20/80 (25%), Positives = 32/80 (40%), Gaps = 9/80 (11%) Query: 42 GWSLPKEKGLIL-CLWNKFCRWFHRRESWAQSRDEQNLLQQKR--IWESPLLLAAKENNV 98 G L KEK +++ C N RW + W Q D NL+ R + P+ A+ Sbjct: 132 GLYLAKEKNMLMTCAVNS--RWLNYGTEWEQYFDYINLMSYDRGAFTDKPVQHASY---- 185 Query: 99 QALIKLLKFEGCEVHQKGAM 118 +K LK+ + + Sbjct: 186 DDFVKDLKYWNEQCRASKSK 205 >2DI3-A nrPDB Length = 239 Score = 29.7 bits (65), Expect = 4.4, Method: Composition-based stats. Identities = 18/92 (19%), Positives = 36/92 (39%), Gaps = 3/92 (3%) Query: 91 LAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDN---LEAAMVLMEAAPELVF 147 L ++++ +++L+ G G+ + I A L + L+ Sbjct: 38 LGVSRSSLREALRVLEALGTISTATGSGPRSGTIITAAPGQALSLSVTLQLVTNQVGHHD 97 Query: 148 EPMTSELYEGQTALHIAVINQNVNLVRALLAR 179 T +L EG ALH + + ++ ALL + Sbjct: 98 IYETRQLLEGWAALHSSAERGDWDVAEALLEK 129 >4BGN-A nrPDB Length = 298 Score = 29.3 bits (64), Expect = 6.0, Method: Composition-based stats. Identities = 19/95 (20%), Positives = 36/95 (37%), Gaps = 1/95 (1%) Query: 533 CWLMAVVILGFASAFYIIFQTEDPDELGHFYDYPMALFSTFELFLTIIDGPANYDVDLPF 592 LM ++ F +F+ P+ G + + LF L + G + F Sbjct: 151 MLLMGLIFYIFGVMGTFLFRDVAPEYFGSLHLSLITLFQVVTLE-SWASGIMRPIMAEVF 209 Query: 593 MYSITYAAFAIIATLLMLNLLIAMMGDTHWRVAHE 627 I + AF ++ T ++ NL + ++ R E Sbjct: 210 WSWIYFVAFILVGTFVIFNLFVGVIVSNVERAETE 244 >2FT0-A nrPDB Length = 235 Score = 29.3 bits (64), Expect = 6.1, Method: Composition-based stats. Identities = 12/47 (25%), Positives = 21/47 (44%) Query: 141 AAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARA 187 A EL+ + G+T L +A N ++ + GA+V + A Sbjct: 184 AGAELMQTALNWAYARGKTTLRVATQMGNTAALKRYIQSGANVESTA 230 >1Y1U-A nrPDB Length = 585 Score = 29.3 bits (64), Expect = 7.1, Method: Composition-based stats. Identities = 13/64 (20%), Positives = 25/64 (39%), Gaps = 4/64 (6%) Query: 626 HERDELWRAQVVATTVMLERKLPRCLWPR-SGICGREYGLGD---RWFLRVEDRQDLNRQ 681 + L + T ++ + + + +G G G D W ++ + NRQ Sbjct: 105 KHQKTLQLLRKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQ 164 Query: 682 RIRR 685 +IRR Sbjct: 165 QIRR 168 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.315 0.131 0.351 Lambda K H 0.267 0.0400 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 28,176,142 Number of Sequences: 36641 Number of extensions: 1085516 Number of successful extensions: 4738 Number of sequences better than 10.0: 98 Number of HSP's better than 10.0 without gapping: 139 Number of HSP's successfully gapped in prelim test: 42 Number of HSP's that attempted gapping in prelim test: 3177 Number of HSP's gapped (non-prelim): 502 length of query: 767 length of database: 10,336,785 effective HSP length: 105 effective length of query: 662 effective length of database: 6,489,480 effective search space: 4296035760 effective search space used: 4296035760 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.1 bits) S2: 63 (28.9 bits)