BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9QYB1 (253 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2D2Z-A nrPDB 514 e-146 4K0G-A nrPDB 336 4e-93 2R5G-A nrPDB 330 4e-91 5Y7I-A nrPDB 320 4e-88 3FY7-A nrPDB 239 1e-63 2YV7-A nrPDB 117 7e-27 5IQY-A nrPDB 94 5e-20 5D9W-A nrPDB 87 6e-18 5LOL-A nrPDB 87 6e-18 5N9U-A nrPDB 82 2e-16 5ELG-A nrPDB 80 6e-16 2YV9-A nrPDB 74 9e-14 4QQ7-A nrPDB 50 7e-07 3M1G-A nrPDB 36 0.017 1FW1-A nrPDB 34 0.057 3LFL-A nrPDB 34 0.059 2CZ2-A nrPDB 33 0.14 5TX1-A nrPDB 33 0.14 3QAG-A nrPDB 33 0.16 2WCU-A nrPDB 32 0.27 4PQI-A nrPDB 32 0.31 3LG6-A nrPDB 32 0.36 2OBE-A nrPDB 31 0.39 3WD6-A nrPDB 31 0.51 4IGJ-A nrPDB 31 0.58 3ZDR-A nrPDB 30 1.1 1P2Z-A nrPDB 29 1.6 5LDN-A nrPDB 29 1.6 3BBY-A nrPDB 29 1.7 2CA8-A nrPDB 28 5.2 4YZB-A nrPDB 27 8.5 >2D2Z-A nrPDB Length = 261 Score = 514 bits (1324), Expect = e-146, Method: Compositional matrix adjust. Identities = 250/253 (98%), Positives = 252/253 (99%) Query: 1 MALSMPLNGLKEEDKEPLIELFVKAGSDGESIGNCPFSQRLFMILWLKGVVFSVTTVDLK 60 MALSMPLNGLKEEDKEPLIELFVKAGSDGESIGNCPFSQRLFMILWLKGVVFSVTTVDLK Sbjct: 1 MALSMPLNGLKEEDKEPLIELFVKAGSDGESIGNCPFSQRLFMILWLKGVVFSVTTVDLK 60 Query: 61 RKPADLQNLAPGTHPPFITFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHPESNTAGMD 120 RKPADLQNLAPGTHPPFITFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHPESNTAGMD Sbjct: 61 RKPADLQNLAPGTHPPFITFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHPESNTAGMD 120 Query: 121 IFAKFSAYIKNSRPEANEALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLD 180 IFAKFSAYIKNSRPEANEALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTR+FLD Sbjct: 121 IFAKFSAYIKNSRPEANEALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRKFLD 180 Query: 181 GDEMTLADCNLLPKLHIVKVVAKKYRNFDIPKGMTGIWRYLTNAYSRDEFTNTCPSDKEV 240 G+EMTLADCNLLPKLHIVKVVAKKYRNFDIPK MTGIWRYLTNAYSRDEFTNTCPSDKEV Sbjct: 181 GNEMTLADCNLLPKLHIVKVVAKKYRNFDIPKEMTGIWRYLTNAYSRDEFTNTCPSDKEV 240 Query: 241 EIAYSDVAKRLTK 253 EIAYSDVAKRLTK Sbjct: 241 EIAYSDVAKRLTK 253 >4K0G-A nrPDB Length = 251 Score = 336 bits (862), Expect = 4e-93, Method: Compositional matrix adjust. Identities = 157/238 (65%), Positives = 190/238 (79%) Query: 14 DKEPLIELFVKAGSDGESIGNCPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAPGT 73 +++P +ELFVKAGSDG IGN PFSQRLFM+LWLKGV F+VTTVD KR+ +Q L PG Sbjct: 13 EEQPQVELFVKAGSDGAKIGNSPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGG 72 Query: 74 HPPFITFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSR 133 PF+ + +EV TD NKIEEFLE VLCPP+Y KL+ +PESNTAG+DIFAKFSAYIKNS Sbjct: 73 QLPFLLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSN 132 Query: 134 PEANEALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLP 193 P N+ LE+GLLK L+ LD YL SPLP+E+DE S ED S R+FLDG+E+TLADCNLLP Sbjct: 133 PALNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLP 192 Query: 194 KLHIVKVVAKKYRNFDIPKGMTGIWRYLTNAYSRDEFTNTCPSDKEVEIAYSDVAKRL 251 KLHIV+VV KKYR F IP+ G+ RYL+NAY+R+EF +TCP D+E+E+AY VAK L Sbjct: 193 KLHIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAKAL 250 >2R5G-A nrPDB Length = 247 Score = 330 bits (846), Expect = 4e-91, Method: Compositional matrix adjust. Identities = 155/235 (65%), Positives = 195/235 (82%) Query: 16 EPLIELFVKAGSDGESIGNCPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAPGTHP 75 +P IELFVKAGSDGESIGNCPF QRLFMILWLKGV F+VTTVD+ RKP +L++LAPGT+P Sbjct: 11 DPEIELFVKAGSDGESIGNCPFCQRLFMILWLKGVKFNVTTVDMTRKPEELKDLAPGTNP 70 Query: 76 PFITFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPE 135 PF+ +N E+KTD KIEEFLE+ L PP+Y LSPK+ ES G ++FAKFSAYIKN++ E Sbjct: 71 PFLVYNKELKTDFIKIEEFLEQTLAPPRYPHLSPKYKESFDVGCNLFAKFSAYIKNTQKE 130 Query: 136 ANEALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKL 195 AN+ E+ LLK ++LD+YLN+PL DEID +S E+ S R FLDGD++TLADC+LLPKL Sbjct: 131 ANKNFEKSLLKEFKRLDDYLNTPLLDEIDPDSAEEPPVSRRLFLDGDQLTLADCSLLPKL 190 Query: 196 HIVKVVAKKYRNFDIPKGMTGIWRYLTNAYSRDEFTNTCPSDKEVEIAYSDVAKR 250 +I+KV AKKYR+FDIP +G+WRYL NAY+R+EFT+TCP DKE+E Y++VAK+ Sbjct: 191 NIIKVAAKKYRDFDIPAEFSGVWRYLHNAYAREEFTHTCPEDKEIENTYANVAKQ 245 >5Y7I-A nrPDB Length = 261 Score = 320 bits (820), Expect = 4e-88, Method: Compositional matrix adjust. Identities = 151/240 (62%), Positives = 188/240 (78%), Gaps = 2/240 (0%) Query: 11 KEEDKEPLIELFVKAGSDGESIGNCPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLA 70 + DKEP IELF+KAG DGE++GNCPF QRLFM+LWLKGV F+VTTVD+++KPA+L++LA Sbjct: 22 QSSDKEPSIELFIKAGHDGENVGNCPFCQRLFMVLWLKGVKFTVTTVDMRKKPAELKDLA 81 Query: 71 PGTHPPFITFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIK 130 PGT+PPF+ +N +KTD KIEEFLE+ L PP+Y LSP + ES G DIFAKFSA+IK Sbjct: 82 PGTNPPFLLYNGTLKTDFIKIEEFLEQTLAPPRYPHLSPVNKESFDVGADIFAKFSAFIK 141 Query: 131 NSRPEANEALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCN 190 NS N E+ LL+ ++LD+YLNSPLP+EID NS+E I S R+FLDGD +TLADCN Sbjct: 142 NS--PNNPLQEKNLLREFKRLDDYLNSPLPEEIDHNSVETITVSNRKFLDGDRLTLADCN 199 Query: 191 LLPKLHIVKVVAKKYRNFDIPKGMTGIWRYLTNAYSRDEFTNTCPSDKEVEIAYSDVAKR 250 LLPKLH+++V AKKY NF+IP TG+WRYL NA RDEF TCP+D E+E AY VA + Sbjct: 200 LLPKLHVIRVAAKKYCNFEIPDHFTGVWRYLKNADERDEFKQTCPADIEIEKAYLSVANK 259 >3FY7-A nrPDB Length = 250 Score = 239 bits (609), Expect = 1e-63, Method: Compositional matrix adjust. Identities = 116/226 (51%), Positives = 154/226 (68%), Gaps = 2/226 (0%) Query: 19 IELFVKAGSDGESIGNCPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAPGTHPPFI 78 ++LFVKA DGES+G+CP QRLFM+L LKGV F++TTVD +R P L++ APG+ P + Sbjct: 26 LQLFVKASEDGESVGHCPSCQRLFMVLLLKGVPFTLTTVDTRRSPDVLKDFAPGSQLPIL 85 Query: 79 TFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEANE 138 ++S+ KTD +IE+FLEE L PP + L+P++ ESNTAG D+F KFSA+IKN P +E Sbjct: 86 LYDSDAKTDTLQIEDFLEETLGPPDFPSLAPRYRESNTAGNDVFHKFSAFIKNPVPAQDE 145 Query: 139 ALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHIV 198 AL + LL+ L +LD YL +PL E+ ++ S RRFLDGD +TLADC+LLPKLHIV Sbjct: 146 ALYQQLLRALARLDSYLRAPLEHEL--AGEPQLRESRRRFLDGDRLTLADCSLLPKLHIV 203 Query: 199 KVVAKKYRNFDIPKGMTGIWRYLTNAYSRDEFTNTCPSDKEVEIAY 244 V +R IP + G+ RYL +A EF TCP E+ AY Sbjct: 204 DTVCAHFRQAPIPAELRGVRRYLDSAMQEKEFKYTCPHSAEILAAY 249 >2YV7-A nrPDB Length = 260 Score = 117 bits (292), Expect = 7e-27, Method: Compositional matrix adjust. Identities = 71/229 (31%), Positives = 114/229 (49%), Gaps = 27/229 (11%) Query: 17 PLIELFVKAGS-DGESIGNCPFSQRLFMILWL----KGVVFSVTTVDLKRKPADLQNLAP 71 P IEL +KA + DG G C F Q FM L+L K + VTTVD+++ P D + Sbjct: 21 PEIELIIKASTIDGRRKGACLFCQEYFMDLYLLAELKTISLKVTTVDMQKPPPDFRTNFE 80 Query: 72 GTHPPFITFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKN 131 THPP + N + KIE + + + P L + E T +++ K + Sbjct: 81 ATHPPILIDNGLAILENEKIERHIMKNI--PGGYNLFVQDKEVATLIENLYVKLKLML-- 136 Query: 132 SRPEANEALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNL 191 + +EA LL L+K++++L++ RFL GD M DC L Sbjct: 137 --VKKDEAKNNALLSHLRKINDHLSA----------------RNTRFLTGDTMCCFDCEL 178 Query: 192 LPKLHIVKVVAKKYRNFDIPKGMTGIWRYLTNAYSRDEFTNTCPSDKEV 240 +P+L ++V K + +F+IP +T +WRY+ + Y D FT +CP+D+++ Sbjct: 179 MPRLQHIRVAGKYFVDFEIPTHLTALWRYMYHMYQLDAFTQSCPADQDI 227 >5IQY-A nrPDB Length = 216 Score = 94.0 bits (232), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 64/222 (28%), Positives = 112/222 (50%), Gaps = 25/222 (11%) Query: 19 IELFVKAGSDGESI-GNCPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAP-GTHPP 76 +E+ VKA I G+CPFSQR+ + L K + + + VDL KP ++P G P Sbjct: 6 VEVCVKAAVGAPDILGDCPFSQRVLLTLEEKKITYEMKLVDLSNKPEWFLKISPEGKVPV 65 Query: 77 FITFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEA 136 F + + + D + I + +EE P + +P PE + G IF F ++K+ +A Sbjct: 66 FNSGDGKWIADSDVITQVIEEKFPTPSLV--TP--PEYASVGSKIFPSFVKFLKSK--DA 119 Query: 137 NEALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLH 196 ++ E+ LL LQ LDE+L + P ++ G+ ++ AD +L PKL Sbjct: 120 SDGSEKALLDELQALDEHLKAHGP-----------------YISGENVSAADLSLGPKLF 162 Query: 197 IVKVVAKKYRNFDIPKGMTGIWRYLTNAYSRDEFTNTCPSDK 238 ++V + ++ + IP+ +T + Y +SR+ F T P+++ Sbjct: 163 HLQVALEHFKGWKIPENLTSVHAYTKALFSRESFVKTKPANQ 204 >5D9W-A nrPDB Length = 230 Score = 87.4 bits (215), Expect = 6e-18, Method: Compositional matrix adjust. Identities = 61/217 (28%), Positives = 111/217 (51%), Gaps = 25/217 (11%) Query: 19 IELFVKAG-SDGESIGNCPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAP-GTHPP 76 +E+ VKA +++G+ PFSQR+ + L K V + + +D++ KP ++P G P Sbjct: 20 VEVCVKAAVGHPDTLGDSPFSQRVLLTLEEKKVPYEMKLIDVQNKPDWFLKISPEGKVPV 79 Query: 77 FITFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEA 136 F + + D + I + +EE P + +P PE + G IF+ F+ ++K+ P Sbjct: 80 FNGGDGKWIPDSDVITQVIEEKYPTPSLV--TP--PEYASVGSKIFSCFTTFLKSKDP-- 133 Query: 137 NEALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLH 196 N+ E+ LL LQ L+E+L + P F++G ++ AD +L PKL+ Sbjct: 134 NDGSEKALLTELQALEEHLKAHGP-----------------FINGQNISAADLSLAPKLY 176 Query: 197 IVKVVAKKYRNFDIPKGMTGIWRYLTNAYSRDEFTNT 233 ++V + ++ + IP+ +T + Y +SR+ F T Sbjct: 177 HLQVALEHFKGWKIPEDLTNVHAYTEALFSRESFIKT 213 >5LOL-A nrPDB Length = 215 Score = 87.4 bits (215), Expect = 6e-18, Method: Compositional matrix adjust. Identities = 59/213 (27%), Positives = 107/213 (50%), Gaps = 25/213 (11%) Query: 32 IGNCPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAPGTHPPFITFNSEVKTDVNKI 91 +G+CPFSQR+ + L K + + +++ KP +++P P + + + D + I Sbjct: 19 LGDCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKLDGKWVADSDVI 78 Query: 92 EEFLEEVLCPPKYLKLSPKHP-ESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTLQK 150 LEE KY + S K P E + G IF F ++K+ +AN+ E+ L+ L+ Sbjct: 79 VGLLEE-----KYPEPSLKTPPEFASVGSKIFGAFVTFLKSK--DANDGSEKALVDELEA 131 Query: 151 LDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHIVKVVAKKYRNFDI 210 L+ +L K + F+ G+++T D +L PKL+ ++V Y+N+ + Sbjct: 132 LENHL----------------KTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSV 175 Query: 211 PKGMTGIWRYLTNAYSRDEFTNTCPSDKEVEIA 243 P+ +T + Y +SR+ F NT + KE+ +A Sbjct: 176 PESLTSVRNYAKALFSRESFENT-KAKKEIVVA 207 >5N9U-A nrPDB Length = 218 Score = 82.4 bits (202), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 61/223 (27%), Positives = 106/223 (47%), Gaps = 24/223 (10%) Query: 19 IELFVKAGSDGESI-GNCPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAPGTHPPF 77 +E+ VKA +I G+CPF QR+ + L K + + ++L KP ++P P Sbjct: 3 LEICVKAAVGAPNILGDCPFCQRVLLSLEEKKIPYKSHLINLGDKPQWFLEISPEGKVPV 62 Query: 78 ITFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEAN 137 + + + D + I LEE P +P PE + G IF F ++K+ P N Sbjct: 63 VKIDDKWVADSDVIVGILEEKNPEPPLA--TP--PEFASVGSKIFPSFVKFLKSKDP--N 116 Query: 138 EALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHI 197 + E+ LL+ L+ LD +L P F+ G+++T D +L PKL+ Sbjct: 117 DGTEQALLEELKALDGHLKVHGP-----------------FIAGEKITAVDLSLAPKLYH 159 Query: 198 VKVVAKKYRNFDIPKGMTGIWRYLTNAYSRDEFTNTCPSDKEV 240 ++V ++N+ IP +T + Y+ +SR+ F T +++ V Sbjct: 160 LEVALGHFKNWPIPDNLTHVLNYIKLLFSRESFKKTRAAEEHV 202 >5ELG-A nrPDB Length = 221 Score = 80.5 bits (197), Expect = 6e-16, Method: Compositional matrix adjust. Identities = 58/224 (25%), Positives = 105/224 (46%), Gaps = 25/224 (11%) Query: 19 IELFVKAGSDG-ESIGNCPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAPGTHPPF 77 +E+ VKA + +G+CPFSQR + L K + + + ++L KP +++P P Sbjct: 3 LEICVKAAVGAPDHLGDCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPV 62 Query: 78 ITFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHP-ESNTAGMDIFAKFSAYIKNSRPEA 136 + + + TD + I LEE KY K P E + G +IF F ++K+ ++ Sbjct: 63 LKIDDKWVTDSDVIVGILEE-----KYPDPPLKTPAEFASVGSNIFGTFGTFLKSK--DS 115 Query: 137 NEALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLH 196 N+ E LL L+ L+ +L S F+ G+ ++ D +L PKL+ Sbjct: 116 NDGSEHALLVELEALENHLKS----------------HDGPFIAGERVSAVDLSLAPKLY 159 Query: 197 IVKVVAKKYRNFDIPKGMTGIWRYLTNAYSRDEFTNTCPSDKEV 240 ++V ++++ +P+ + Y+ +S D F T +K V Sbjct: 160 HLQVALGHFKSWSVPESFPHVHNYMKTLFSLDSFEKTKTEEKYV 203 >2YV9-A nrPDB Length = 291 Score = 73.6 bits (179), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 65/269 (24%), Positives = 115/269 (42%), Gaps = 43/269 (15%) Query: 1 MALSMPLNGLKEEDKEPLIELFVKA-GSDGESIGNCPFSQRLFMILWLKGVVFSVTTVDL 59 MA + + + +PL+EL+VKA G D IG F Q +M L+ ++ + + Sbjct: 2 MAEAYQIQSNGDPQSKPLLELYVKASGIDARRIGADLFCQEFWMELY---ALYEIGVARV 58 Query: 60 KRKPADLQNLA-----PGTHPPFI---------TFNSEVKTDVNKIEEFLEEVLCPPKYL 105 + K ++ + A G PP + T N E++ +I +E P Sbjct: 59 EVKTVNVNSEAFKKNFLGAQPPIMIEEEKELTYTDNREIE---GRIFHLAKEFNVP---- 111 Query: 106 KLSPKHPESNTAGMDIFAKFSAYIK--------NSRPEANEALERGLLKTLQKLDEYLNS 157 L K P + +++ F +++ P E L + ++ E L++ Sbjct: 112 -LFEKDPSAEKRIENLYRNFKLFLRAKVEFDKGKKEPSRVEDLPAQIKVHYNRVCEQLSN 170 Query: 158 PLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHIVKVVAKKYRNFDIPKGMTGI 217 ID+ E R+L G+ MT DC L+P+LH ++++ FDIP T + Sbjct: 171 -----IDQLLSE----RKSRYLLGNSMTEYDCELMPRLHHIRIIGLSLLGFDIPHNFTHL 221 Query: 218 WRYLTNAYSRDEFTNTCPSDKEVEIAYSD 246 W Y+ AY F +CP+D+++ Y + Sbjct: 222 WAYILTAYRTAAFIESCPADQDIIHHYKE 250 >4QQ7-A nrPDB Length = 207 Score = 50.4 bits (119), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 43/207 (20%), Positives = 85/207 (41%), Gaps = 18/207 (8%) Query: 34 NCPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAPGTHPPFITFNSEVKTDVNKIEE 93 CPFSQR ++L+ KG+ F + VDL KP D+ + P P + + + N I E Sbjct: 13 TCPFSQRCRLVLFEKGMDFEIRDVDLFNKPEDISVMNPYGQVPILVERDLILYESNIINE 72 Query: 94 FLEEVLCPPKYLKLSP-KHPESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTLQKLD 152 +++E P+ + P + + ++ + ++ E +A E+ K + Sbjct: 73 YIDERFPHPQLMPADPVQRARARLFLLNFEKELFVHVSTLENEKGKAAEKNHEKARLAIR 132 Query: 153 EYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHIVKVVAKKYRNFDIPK 212 + L P F +++ G+E ++ D + P L + + ++ K Sbjct: 133 DRLTQLAP-----------IFVKNKYMLGEEFSMLDVAIAPLLWRL-----DHYGIELSK 176 Query: 213 GMTGIWRYLTNAYSRDEFTNT-CPSDK 238 + +Y +SR + PS+K Sbjct: 177 NAAPLMKYAERIFSRPAYIEALTPSEK 203 >3M1G-A nrPDB Length = 362 Score = 35.8 bits (81), Expect = 0.017, Method: Compositional matrix adjust. Identities = 24/71 (33%), Positives = 36/71 (50%), Gaps = 7/71 (9%) Query: 168 MEDIKFSTRRFLDGDEMTLADCNLLPKLHIVKVVAKKYRNFDIPKG----MTGIWRYLTN 223 +ED + STRR+L GD +T AD L P L V+ A + +F + M +W YL + Sbjct: 226 LED-RLSTRRYLMGDHITEADIRLYPTL--VRFDAVYHGHFKCGRNKITEMPNLWGYLRD 282 Query: 224 AYSRDEFTNTC 234 + F +T Sbjct: 283 LFQTPGFGDTT 293 >1FW1-A nrPDB Length = 216 Score = 34.3 bits (77), Expect = 0.057, Method: Compositional matrix adjust. Identities = 41/167 (24%), Positives = 68/167 (40%), Gaps = 22/167 (13%) Query: 38 SQRLFMILWLKGVVFSVTTVDL-----KRKPADLQNLAPGTHPPFITFNSEVKTDVNKIE 92 S R+ + L LKG+ + ++L ++ D Q L P P + + I Sbjct: 17 SWRVRIALALKGIDYKTVPINLIKDGGQQFSKDFQALNPMKQVPTLKIDGITIHQSLAII 76 Query: 93 EFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTLQKLD 152 E+LEE P+ L PK S D+ A ++N L L+++ Sbjct: 77 EYLEETRPTPRLLPQDPKKRASVRMISDLIAGGIQPLQN-------------LSVLKQVG 123 Query: 153 EYLNSPLPDE---IDENSMEDIKFSTRR-FLDGDEMTLADCNLLPKL 195 E + N++E I ST + GDE+T+AD L+P++ Sbjct: 124 EEMQLTWAQNAITCGFNALEQILQSTAGIYCVGDEVTMADLCLVPQV 170 >3LFL-A nrPDB Length = 240 Score = 34.3 bits (77), Expect = 0.059, Method: Compositional matrix adjust. Identities = 43/181 (23%), Positives = 74/181 (40%), Gaps = 8/181 (4%) Query: 31 SIGNCPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAP-GTHPPFITFNSEVKTDVN 89 S+ CPF++R ++L KG+ V ++LK KP P G P ++ + Sbjct: 28 SMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESA 87 Query: 90 KIEEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAK----FSAYIKNSRPEANEALERGLL 145 E+L+E K L P +++F+K ++I++ E L+ Sbjct: 88 ITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFR 147 Query: 146 KTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDE-MTLADC-NLLPKLHIVKVVAK 203 K KL E L + NS+ I + + + E M L +C + PKL + K Sbjct: 148 KEFTKL-EVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMK 206 Query: 204 K 204 + Sbjct: 207 E 207 >2CZ2-A nrPDB Length = 223 Score = 32.7 bits (73), Expect = 0.14, Method: Compositional matrix adjust. Identities = 40/167 (23%), Positives = 73/167 (43%), Gaps = 22/167 (13%) Query: 38 SQRLFMILWLKGVVFSVTTVDLKRKPA-----DLQNLAPGTHPPFITFNSEVKTDVNKIE 92 S R+ + L LKG+ + + ++L + + Q L P P + + I Sbjct: 24 SWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSLAIM 83 Query: 93 EFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNS-RPEANEAL--ERGLLKTLQ 149 E+LEE P+ L P+ P+ I S I + +P N ++ + G +Q Sbjct: 84 EYLEETRPIPRLL---PQDPQKRA----IVRMISDLIASGIQPLQNLSVLKQVGQENQMQ 136 Query: 150 KLDEYLNSPLPDEIDENSMEDIKFSTR-RFLDGDEMTLADCNLLPKL 195 + + S N++E I ST ++ GDE+++AD L+P++ Sbjct: 137 WAQKVITSGF------NALEKILQSTAGKYCVGDEVSMADVCLVPQV 177 >5TX1-A nrPDB Length = 952 Score = 32.7 bits (73), Expect = 0.14, Method: Compositional matrix adjust. Identities = 23/80 (28%), Positives = 39/80 (48%), Gaps = 13/80 (16%) Query: 172 KFSTRRFLDGDEMTLADCNLLPKLHIVKVVAK---KYRNFDIPKGMTGIWRYLTNAYSRD 228 +F +R +DG+ +A CN+ +V++++ Y+ F +P+G Y YS Sbjct: 742 EFEIKRSVDGEGYNVAQCNMTKDWFLVQMLSHYNIGYQGFHVPEG------YKDRMYSF- 794 Query: 229 EFTNTCPSDKEV--EIAYSD 246 F N P ++V EI Y D Sbjct: 795 -FRNFQPMSRQVVDEINYKD 813 >3QAG-A nrPDB Length = 239 Score = 32.7 bits (73), Expect = 0.16, Method: Compositional matrix adjust. Identities = 38/164 (23%), Positives = 64/164 (39%), Gaps = 12/164 (7%) Query: 31 SIGNCPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAPGTHPPFI-TFNSEVKTDVN 89 S+ CP+S R ++L K + V ++L+ KP P H P + T S++ + Sbjct: 28 SMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQSQLIYESV 87 Query: 90 KIEEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTLQ 149 E+L++ K P +++F+K K E AL G T Sbjct: 88 IACEYLDDAYPGRKLFPYDPYERARQKMLLELFSKVPHLTK----ECLVALRSGREST-- 141 Query: 150 KLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLP 193 L + L E N E +++ F G +++ D L P Sbjct: 142 ----NLKAALRQEFS-NLEEILEYQNTTFFGGTSISMIDYLLWP 180 >2WCU-A nrPDB Length = 149 Score = 32.0 bits (71), Expect = 0.27, Method: Compositional matrix adjust. Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 6/75 (8%) Query: 170 DIKFSTRRFLDGDEMTLADCNLLPKLHIVKV--VAKKYRNFDIPKGMTGIWRYL---TNA 224 ++ F+ R GDE+ LAD N P I + V + DIP+ + + R L T Sbjct: 14 ELLFALARMGHGDEIVLADAN-FPTSSICQCGPVEIRADGLDIPQLLEAVLRLLPLDTYV 72 Query: 225 YSRDEFTNTCPSDKE 239 S + PSDKE Sbjct: 73 ESPAAVMDLVPSDKE 87 >4PQI-A nrPDB Length = 241 Score = 31.6 bits (70), Expect = 0.31, Method: Compositional matrix adjust. Identities = 43/210 (20%), Positives = 81/210 (38%), Gaps = 21/210 (10%) Query: 34 NCPFSQRLFMILWLKGVVFSVTTVDL--KRKPADL-QNLAPGTHPPFITFNSEVKTDVNK 90 CPF+QR+++ KG+ + V L + +PA + + P P + N ++ + Sbjct: 40 TCPFAQRVWITRNFKGLQDEIKLVPLILQNRPAWYPEKVYPPNKVPSLEHNGKITGESLD 99 Query: 91 IEEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTLQK 150 + ++LE P L PK P ++F+ Y A + L K Sbjct: 100 LIKYLESNFEGPSLL---PKDPAKKEFAEELFS----YTDKFNGTVYTAFKGDLAKEAGP 152 Query: 151 LDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHIVKVVAKKYRNFDI 210 ++L EN++ KF F G E +L D +P + + + + +DI Sbjct: 153 AFDHL---------ENALH--KFDDGPFFLGKEFSLVDIAYIPFVERLNIFLLEVFKYDI 201 Query: 211 PKGMTGIWRYLTNAYSRDEFTNTCPSDKEV 240 G + ++ + + T KE+ Sbjct: 202 TAGRQKLAAWIEEVNKIEAYKQTKTDPKEL 231 >3LG6-A nrPDB Length = 235 Score = 31.6 bits (70), Expect = 0.36, Method: Compositional matrix adjust. Identities = 16/42 (38%), Positives = 22/42 (52%) Query: 171 IKFSTRRFLDGDEMTLADCNLLPKLHIVKVVAKKYRNFDIPK 212 ++ S RF GDE+TLAD L+P + + V F I K Sbjct: 165 LELSAGRFCVGDEITLADVCLVPAVWAAERVGMDLARFPITK 206 >2OBE-A nrPDB Length = 932 Score = 31.2 bits (69), Expect = 0.39, Method: Composition-based stats. Identities = 23/80 (28%), Positives = 39/80 (48%), Gaps = 13/80 (16%) Query: 172 KFSTRRFLDGDEMTLADCNLLPKLHIVKVVAK---KYRNFDIPKGMTGIWRYLTNAYSRD 228 +F +R +DG+ +A CN+ +V+++A Y+ F +P+G Y YS Sbjct: 722 EFEIKRTVDGEGYNVAQCNMTKDWFLVQMLAHYNIGYQGFYVPEG------YKDRMYSF- 774 Query: 229 EFTNTCPSDKEV--EIAYSD 246 F N P ++V E+ Y D Sbjct: 775 -FRNFQPMSRQVVDEVNYKD 793 >3WD6-A nrPDB Length = 256 Score = 30.8 bits (68), Expect = 0.51, Method: Compositional matrix adjust. Identities = 52/194 (26%), Positives = 78/194 (40%), Gaps = 22/194 (11%) Query: 35 CPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAPGTHPPFITFNSEVKTDVNKIE-- 92 CP++QR + L K + + V +DL KP L + P I E+ DV E Sbjct: 38 CPYAQRTILALNAKQIDYEVVNIDLIDKPEWLTTKSAFAKVPAI----EIAEDVTIYESL 93 Query: 93 ---EFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTLQ 149 E+L+EV PK L P+ P A I + SA I ++L +LK Sbjct: 94 VTVEYLDEVY--PK-RPLLPQDP-LKKALDKIIVEASAPI--------QSLFIKILKFSD 141 Query: 150 KLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHIVKVVAKKYRNFD 209 ++E + +D E +K FLDG E AD + P ++ A R Sbjct: 142 TVNEEHVAAYHKALD-FIQEQLKNRGTVFLDGSEPGYADYMIWPWFERLRAFAHDERVRL 200 Query: 210 IPKGMTGIWRYLTN 223 P + + Y+ N Sbjct: 201 EPSKYSLLLEYIDN 214 >4IGJ-A nrPDB Length = 242 Score = 30.8 bits (68), Expect = 0.58, Method: Compositional matrix adjust. Identities = 44/175 (25%), Positives = 76/175 (43%), Gaps = 31/175 (17%) Query: 38 SQRLFMILWLKGVVFSVTTVDL---KRKPADLQNLAPGTHPPFITFNSEVKTDV----NK 90 + R+ + L LKG+ + VDL ++ A Q P + P + + +T + Sbjct: 36 AWRVRLGLALKGLAYEYRAVDLLAQEQFQAAHQARNPMSQVPVLEVEEDGRTHLLVQSMA 95 Query: 91 IEEFLEEVLCPPKYLKLSPKHPESNTAGMDIF--AKFSAYIKN----SRPEANEALERGL 144 I E+LEE +HPE D++ A+ A ++ ++P N + R L Sbjct: 96 ILEWLEE------------RHPEPALLPPDLWGRARVRALAEHVNSGTQPMQNALVLRML 143 Query: 145 LKTLQKLD-EYLNSPLPDEID--ENSMEDIKFSTRRFLDGDEMTLADCNLLPKLH 196 + + D E+ + + E ++ D RF GD TLADC L+P+L+ Sbjct: 144 REKVPGWDREWARFFIARGLAALETAVRD---GAGRFSHGDAPTLADCYLVPQLY 195 >3ZDR-A nrPDB Length = 433 Score = 30.0 bits (66), Expect = 1.1, Method: Compositional matrix adjust. Identities = 21/74 (28%), Positives = 37/74 (50%), Gaps = 5/74 (6%) Query: 99 LCPPKYLKLSPKHPESNTAGMDIFAK-FSAYIKNSRPEANEALERGLLKTLQKLDEYLNS 157 + P+++ PKH ++T GMD+ AY+ N AN+ + +K +Q + EYL Sbjct: 205 IVDPQFVMTVPKHVTADT-GMDVLTHAIEAYVSNM---ANDYTDGLAMKAIQLVFEYLPR 260 Query: 158 PLPDEIDENSMEDI 171 + DE + E + Sbjct: 261 AYQNGADELAREKM 274 >1P2Z-A nrPDB Length = 967 Score = 29.3 bits (64), Expect = 1.6, Method: Compositional matrix adjust. Identities = 13/44 (29%), Positives = 25/44 (56%), Gaps = 3/44 (6%) Query: 172 KFSTRRFLDGDEMTLADCNLLPKLHIVKVVAK---KYRNFDIPK 212 +F +R +DG+ +A CN+ +V+++A Y+ F IP+ Sbjct: 757 EFEIKRSVDGEGYNVAQCNMTKDWFLVQMLANYNIGYQGFYIPE 800 >5LDN-A nrPDB Length = 927 Score = 29.3 bits (64), Expect = 1.6, Method: Compositional matrix adjust. Identities = 13/44 (29%), Positives = 25/44 (56%), Gaps = 3/44 (6%) Query: 172 KFSTRRFLDGDEMTLADCNLLPKLHIVKVVAK---KYRNFDIPK 212 +F +R +DG+ +A CN+ +V+++A Y+ F IP+ Sbjct: 722 EFEIKRSVDGEGYNVAQCNMTKDWFLVQMLANYNIGYQGFYIPE 765 >3BBY-A nrPDB Length = 215 Score = 29.3 bits (64), Expect = 1.7, Method: Compositional matrix adjust. Identities = 23/106 (21%), Positives = 43/106 (40%), Gaps = 6/106 (5%) Query: 35 CPFSQRLFMILWLKGVVFSVTTVDL---KRKPADLQNLAPGTHPPFITFNSEVKTDVNKI 91 P+ ++ L KG+ F + T+DL + Q P + + ++ + I Sbjct: 17 SPYVLSAWVALQEKGLSFHIKTIDLDSGEHLQPTWQGYGQTRRVPLLQIDDFELSESSAI 76 Query: 92 EEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAY---IKNSRP 134 E+LE+ PP + ++ P E+ I A + I+ RP Sbjct: 77 AEYLEDRFAPPTWERIYPLDLENRARARQIQAWLRSDLMPIREERP 122 >2CA8-A nrPDB Length = 211 Score = 27.7 bits (60), Expect = 5.2, Method: Compositional matrix adjust. Identities = 23/63 (36%), Positives = 31/63 (49%), Gaps = 9/63 (14%) Query: 138 EALERGLLKTLQK--------LDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADC 189 E LE KTL K + E LN +P +D E +K ST + GD++TLAD Sbjct: 103 EDLEHEYYKTLMKPEEEKQKIIKEILNGKVPVLLD-IICESLKASTGKLAVGDKVTLADL 161 Query: 190 NLL 192 L+ Sbjct: 162 VLI 164 >4YZB-A nrPDB Length = 491 Score = 26.9 bits (58), Expect = 8.5, Method: Compositional matrix adjust. Identities = 20/70 (28%), Positives = 29/70 (41%), Gaps = 8/70 (11%) Query: 109 PKHPESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTLQKLDEYLNSPLPDEIDENSM 168 P+ + + D+ K AY+ R A +ALE LKT D ID S+ Sbjct: 253 PQWKKVSEPAKDLIRKMLAYVPTMRISARDALEHEWLKT--------TDAATDSIDVPSL 304 Query: 169 EDIKFSTRRF 178 E + R+F Sbjct: 305 ESTILNIRQF 314 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2D2Z-A nrPDB 367 e-102 5Y7I-A nrPDB 327 4e-90 2R5G-A nrPDB 324 3e-89 4K0G-A nrPDB 321 2e-88 3FY7-A nrPDB 279 8e-76 5IQY-A nrPDB 239 9e-64 5N9U-A nrPDB 237 3e-63 5D9W-A nrPDB 233 4e-62 5ELG-A nrPDB 233 6e-62 2YV7-A nrPDB 233 7e-62 2YV9-A nrPDB 231 3e-61 5LOL-A nrPDB 227 4e-60 4QQ7-A nrPDB 186 8e-48 Sequences not found previously or not previously below threshold: 3LFL-A nrPDB 81 4e-16 4PQI-A nrPDB 79 1e-15 2CZ2-A nrPDB 76 2e-14 3QAG-A nrPDB 73 1e-13 1FW1-A nrPDB 71 4e-13 4J2F-A nrPDB 71 4e-13 2VO4-A nrPDB 69 2e-12 4CHS-A nrPDB 68 4e-12 5J5N-A nrPDB 68 5e-12 3WD6-A nrPDB 67 7e-12 1AW9-A nrPDB 64 5e-11 1E6B-A nrPDB 61 4e-10 5NR1-A nrPDB 61 5e-10 4AGS-A nrPDB 60 1e-09 3UBL-A nrPDB 59 2e-09 2JL4-A nrPDB 59 3e-09 3IBH-A nrPDB 56 1e-08 3R2Q-A nrPDB 54 8e-08 5EY6-A nrPDB 53 1e-07 5F07-A nrPDB 52 2e-07 5F06-A nrPDB 52 3e-07 4IGJ-A nrPDB 51 4e-07 1GWC-A nrPDB 51 6e-07 4RI7-A nrPDB 51 7e-07 1OYJ-A nrPDB 50 9e-07 1PN9-A nrPDB 50 1e-06 3LG6-A nrPDB 49 1e-06 4MK3-A nrPDB 49 2e-06 3BBY-A nrPDB 49 2e-06 3RBT-A nrPDB 49 2e-06 6F05-A nrPDB 49 2e-06 2PMT-A nrPDB 49 3e-06 1JLV-A nrPDB 48 4e-06 5F05-A nrPDB 48 5e-06 3MAK-A nrPDB 47 6e-06 5ZWP-A nrPDB 46 1e-05 3M1G-A nrPDB 46 2e-05 3NIV-A nrPDB 46 2e-05 5F0G-A nrPDB 46 2e-05 1F2E-A nrPDB 45 3e-05 6JWK-A nrPDB 44 5e-05 4PXO-A nrPDB 44 5e-05 2GDR-A nrPDB 44 5e-05 1AXD-A nrPDB 44 7e-05 4PTS-A nrPDB 43 1e-04 5A5K-A nrPDB 43 1e-04 3IR4-A nrPDB 43 1e-04 1U3I-A nrPDB 42 2e-04 6N0I-A nrPDB 42 2e-04 2GLR-A nrPDB 42 2e-04 2CA8-A nrPDB 42 2e-04 1V2A-A nrPDB 42 2e-04 3VWX-A nrPDB 42 3e-04 3PR8-A nrPDB 41 5e-04 6GZF-A nrPDB 40 0.001 18GS-A nrPDB 38 0.003 2C3Q-A nrPDB 38 0.003 1G6W-A nrPDB 37 0.006 4MDC-A nrPDB 36 0.019 4FN5-A nrPDB 36 0.021 4USS-A nrPDB 35 0.030 2IL3-A nrPDB 35 0.037 4LMW-A nrPDB 34 0.048 2PVQ-A nrPDB 34 0.057 2PPQ-A nrPDB 34 0.077 4FQU-A nrPDB 32 0.23 3PL2-A nrPDB 31 0.48 2PBJ-A nrPDB 31 0.50 6GCB-A nrPDB 31 0.64 3QMX-A nrPDB 30 0.95 4G0L-A nrPDB 29 1.6 6A94-A nrPDB 29 2.8 4IP6-A nrPDB 27 6.0 >2D2Z-A nrPDB Length = 261 Score = 367 bits (941), Expect = e-102, Method: Composition-based stats. Identities = 250/253 (98%), Positives = 252/253 (99%) Query: 1 MALSMPLNGLKEEDKEPLIELFVKAGSDGESIGNCPFSQRLFMILWLKGVVFSVTTVDLK 60 MALSMPLNGLKEEDKEPLIELFVKAGSDGESIGNCPFSQRLFMILWLKGVVFSVTTVDLK Sbjct: 1 MALSMPLNGLKEEDKEPLIELFVKAGSDGESIGNCPFSQRLFMILWLKGVVFSVTTVDLK 60 Query: 61 RKPADLQNLAPGTHPPFITFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHPESNTAGMD 120 RKPADLQNLAPGTHPPFITFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHPESNTAGMD Sbjct: 61 RKPADLQNLAPGTHPPFITFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHPESNTAGMD 120 Query: 121 IFAKFSAYIKNSRPEANEALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLD 180 IFAKFSAYIKNSRPEANEALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTR+FLD Sbjct: 121 IFAKFSAYIKNSRPEANEALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRKFLD 180 Query: 181 GDEMTLADCNLLPKLHIVKVVAKKYRNFDIPKGMTGIWRYLTNAYSRDEFTNTCPSDKEV 240 G+EMTLADCNLLPKLHIVKVVAKKYRNFDIPK MTGIWRYLTNAYSRDEFTNTCPSDKEV Sbjct: 181 GNEMTLADCNLLPKLHIVKVVAKKYRNFDIPKEMTGIWRYLTNAYSRDEFTNTCPSDKEV 240 Query: 241 EIAYSDVAKRLTK 253 EIAYSDVAKRLTK Sbjct: 241 EIAYSDVAKRLTK 253 >5Y7I-A nrPDB Length = 261 Score = 327 bits (837), Expect = 4e-90, Method: Composition-based stats. Identities = 151/240 (62%), Positives = 188/240 (78%), Gaps = 2/240 (0%) Query: 11 KEEDKEPLIELFVKAGSDGESIGNCPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLA 70 + DKEP IELF+KAG DGE++GNCPF QRLFM+LWLKGV F+VTTVD+++KPA+L++LA Sbjct: 22 QSSDKEPSIELFIKAGHDGENVGNCPFCQRLFMVLWLKGVKFTVTTVDMRKKPAELKDLA 81 Query: 71 PGTHPPFITFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIK 130 PGT+PPF+ +N +KTD KIEEFLE+ L PP+Y LSP + ES G DIFAKFSA+IK Sbjct: 82 PGTNPPFLLYNGTLKTDFIKIEEFLEQTLAPPRYPHLSPVNKESFDVGADIFAKFSAFIK 141 Query: 131 NSRPEANEALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCN 190 NS N E+ LL+ ++LD+YLNSPLP+EID NS+E I S R+FLDGD +TLADCN Sbjct: 142 NS--PNNPLQEKNLLREFKRLDDYLNSPLPEEIDHNSVETITVSNRKFLDGDRLTLADCN 199 Query: 191 LLPKLHIVKVVAKKYRNFDIPKGMTGIWRYLTNAYSRDEFTNTCPSDKEVEIAYSDVAKR 250 LLPKLH+++V AKKY NF+IP TG+WRYL NA RDEF TCP+D E+E AY VA + Sbjct: 200 LLPKLHVIRVAAKKYCNFEIPDHFTGVWRYLKNADERDEFKQTCPADIEIEKAYLSVANK 259 >2R5G-A nrPDB Length = 247 Score = 324 bits (830), Expect = 3e-89, Method: Composition-based stats. Identities = 155/237 (65%), Positives = 195/237 (82%) Query: 14 DKEPLIELFVKAGSDGESIGNCPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAPGT 73 +P IELFVKAGSDGESIGNCPF QRLFMILWLKGV F+VTTVD+ RKP +L++LAPGT Sbjct: 9 QVDPEIELFVKAGSDGESIGNCPFCQRLFMILWLKGVKFNVTTVDMTRKPEELKDLAPGT 68 Query: 74 HPPFITFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSR 133 +PPF+ +N E+KTD KIEEFLE+ L PP+Y LSPK+ ES G ++FAKFSAYIKN++ Sbjct: 69 NPPFLVYNKELKTDFIKIEEFLEQTLAPPRYPHLSPKYKESFDVGCNLFAKFSAYIKNTQ 128 Query: 134 PEANEALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLP 193 EAN+ E+ LLK ++LD+YLN+PL DEID +S E+ S R FLDGD++TLADC+LLP Sbjct: 129 KEANKNFEKSLLKEFKRLDDYLNTPLLDEIDPDSAEEPPVSRRLFLDGDQLTLADCSLLP 188 Query: 194 KLHIVKVVAKKYRNFDIPKGMTGIWRYLTNAYSRDEFTNTCPSDKEVEIAYSDVAKR 250 KL+I+KV AKKYR+FDIP +G+WRYL NAY+R+EFT+TCP DKE+E Y++VAK+ Sbjct: 189 KLNIIKVAAKKYRDFDIPAEFSGVWRYLHNAYAREEFTHTCPEDKEIENTYANVAKQ 245 >4K0G-A nrPDB Length = 251 Score = 321 bits (822), Expect = 2e-88, Method: Composition-based stats. Identities = 157/238 (65%), Positives = 190/238 (79%) Query: 14 DKEPLIELFVKAGSDGESIGNCPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAPGT 73 +++P +ELFVKAGSDG IGN PFSQRLFM+LWLKGV F+VTTVD KR+ +Q L PG Sbjct: 13 EEQPQVELFVKAGSDGAKIGNSPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGG 72 Query: 74 HPPFITFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSR 133 PF+ + +EV TD NKIEEFLE VLCPP+Y KL+ +PESNTAG+DIFAKFSAYIKNS Sbjct: 73 QLPFLLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSN 132 Query: 134 PEANEALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLP 193 P N+ LE+GLLK L+ LD YL SPLP+E+DE S ED S R+FLDG+E+TLADCNLLP Sbjct: 133 PALNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLP 192 Query: 194 KLHIVKVVAKKYRNFDIPKGMTGIWRYLTNAYSRDEFTNTCPSDKEVEIAYSDVAKRL 251 KLHIV+VV KKYR F IP+ G+ RYL+NAY+R+EF +TCP D+E+E+AY VAK L Sbjct: 193 KLHIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAKAL 250 >3FY7-A nrPDB Length = 250 Score = 279 bits (713), Expect = 8e-76, Method: Composition-based stats. Identities = 119/244 (48%), Positives = 160/244 (65%), Gaps = 4/244 (1%) Query: 2 ALSMPLNGLKEEDKEPLIELFVKAGSDGESIGNCPFSQRLFMILWLKGVVFSVTTVDLKR 61 AL + G + + ++LFVKA DGES+G+CP QRLFM+L LKGV F++TTVD +R Sbjct: 11 ALEVLFQGPGMAETK--LQLFVKASEDGESVGHCPSCQRLFMVLLLKGVPFTLTTVDTRR 68 Query: 62 KPADLQNLAPGTHPPFITFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHPESNTAGMDI 121 P L++ APG+ P + ++S+ KTD +IE+FLEE L PP + L+P++ ESNTAG D+ Sbjct: 69 SPDVLKDFAPGSQLPILLYDSDAKTDTLQIEDFLEETLGPPDFPSLAPRYRESNTAGNDV 128 Query: 122 FAKFSAYIKNSRPEANEALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDG 181 F KFSA+IKN P +EAL + LL+ L +LD YL +PL E+ ++ S RRFLDG Sbjct: 129 FHKFSAFIKNPVPAQDEALYQQLLRALARLDSYLRAPLEHEL--AGEPQLRESRRRFLDG 186 Query: 182 DEMTLADCNLLPKLHIVKVVAKKYRNFDIPKGMTGIWRYLTNAYSRDEFTNTCPSDKEVE 241 D +TLADC+LLPKLHIV V +R IP + G+ RYL +A EF TCP E+ Sbjct: 187 DRLTLADCSLLPKLHIVDTVCAHFRQAPIPAELRGVRRYLDSAMQEKEFKYTCPHSAEIL 246 Query: 242 IAYS 245 AY Sbjct: 247 AAYR 250 >5IQY-A nrPDB Length = 216 Score = 239 bits (609), Expect = 9e-64, Method: Composition-based stats. Identities = 62/229 (27%), Positives = 112/229 (48%), Gaps = 25/229 (10%) Query: 19 IELFVKAGSDGESI-GNCPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAPGTHPP- 76 +E+ VKA I G+CPFSQR+ + L K + + + VDL KP ++P P Sbjct: 6 VEVCVKAAVGAPDILGDCPFSQRVLLTLEEKKITYEMKLVDLSNKPEWFLKISPEGKVPV 65 Query: 77 FITFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEA 136 F + + + D + I + +EE P + PE + G IF F ++K+ +A Sbjct: 66 FNSGDGKWIADSDVITQVIEEKFPTPSLVTP----PEYASVGSKIFPSFVKFLKSK--DA 119 Query: 137 NEALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLH 196 ++ E+ LL LQ LDE+L + P ++ G+ ++ AD +L PKL Sbjct: 120 SDGSEKALLDELQALDEHLKAHGP-----------------YISGENVSAADLSLGPKLF 162 Query: 197 IVKVVAKKYRNFDIPKGMTGIWRYLTNAYSRDEFTNTCPSDKEVEIAYS 245 ++V + ++ + IP+ +T + Y +SR+ F T P+++ + ++ Sbjct: 163 HLQVALEHFKGWKIPENLTSVHAYTKALFSRESFVKTKPANQYLIAGWA 211 >5N9U-A nrPDB Length = 218 Score = 237 bits (605), Expect = 3e-63, Method: Composition-based stats. Identities = 60/228 (26%), Positives = 105/228 (46%), Gaps = 24/228 (10%) Query: 19 IELFVKAGSDGESI-GNCPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAPGTHPPF 77 +E+ VKA +I G+CPF QR+ + L K + + ++L KP ++P P Sbjct: 3 LEICVKAAVGAPNILGDCPFCQRVLLSLEEKKIPYKSHLINLGDKPQWFLEISPEGKVPV 62 Query: 78 ITFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEAN 137 + + + D + I LEE P PE + G IF F ++K+ P N Sbjct: 63 VKIDDKWVADSDVIVGILEEKNPEPPLATP----PEFASVGSKIFPSFVKFLKSKDP--N 116 Query: 138 EALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHI 197 + E+ LL+ L+ LD +L P F+ G+++T D +L PKL+ Sbjct: 117 DGTEQALLEELKALDGHLKVHGP-----------------FIAGEKITAVDLSLAPKLYH 159 Query: 198 VKVVAKKYRNFDIPKGMTGIWRYLTNAYSRDEFTNTCPSDKEVEIAYS 245 ++V ++N+ IP +T + Y+ +SR+ F T +++ V + Sbjct: 160 LEVALGHFKNWPIPDNLTHVLNYIKLLFSRESFKKTRAAEEHVIAGWE 207 >5D9W-A nrPDB Length = 230 Score = 233 bits (595), Expect = 4e-62, Method: Composition-based stats. Identities = 59/229 (25%), Positives = 113/229 (49%), Gaps = 25/229 (10%) Query: 19 IELFVKAGSD-GESIGNCPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAPGTHPP- 76 +E+ VKA +++G+ PFSQR+ + L K V + + +D++ KP ++P P Sbjct: 20 VEVCVKAAVGHPDTLGDSPFSQRVLLTLEEKKVPYEMKLIDVQNKPDWFLKISPEGKVPV 79 Query: 77 FITFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEA 136 F + + D + I + +EE P + PE + G IF+ F+ ++K+ P Sbjct: 80 FNGGDGKWIPDSDVITQVIEEKYPTPSLVTP----PEYASVGSKIFSCFTTFLKSKDP-- 133 Query: 137 NEALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLH 196 N+ E+ LL LQ L+E+L + P F++G ++ AD +L PKL+ Sbjct: 134 NDGSEKALLTELQALEEHLKAHGP-----------------FINGQNISAADLSLAPKLY 176 Query: 197 IVKVVAKKYRNFDIPKGMTGIWRYLTNAYSRDEFTNTCPSDKEVEIAYS 245 ++V + ++ + IP+ +T + Y +SR+ F T + + + ++ Sbjct: 177 HLQVALEHFKGWKIPEDLTNVHAYTEALFSRESFIKTKAAKEHLIAGWA 225 >5ELG-A nrPDB Length = 221 Score = 233 bits (594), Expect = 6e-62, Method: Composition-based stats. Identities = 55/228 (24%), Positives = 104/228 (45%), Gaps = 23/228 (10%) Query: 19 IELFVKAGSDGE-SIGNCPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAPGTHPPF 77 +E+ VKA +G+CPFSQR + L K + + + ++L KP +++P P Sbjct: 3 LEICVKAAVGAPDHLGDCPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPV 62 Query: 78 ITFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEAN 137 + + + TD + I LEE P + E + G +IF F ++K+ ++N Sbjct: 63 LKIDDKWVTDSDVIVGILEEKYPDPPLKTPA----EFASVGSNIFGTFGTFLKSK--DSN 116 Query: 138 EALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHI 197 + E LL L+ L+ +L S F+ G+ ++ D +L PKL+ Sbjct: 117 DGSEHALLVELEALENHLKSH----------------DGPFIAGERVSAVDLSLAPKLYH 160 Query: 198 VKVVAKKYRNFDIPKGMTGIWRYLTNAYSRDEFTNTCPSDKEVEIAYS 245 ++V ++++ +P+ + Y+ +S D F T +K V ++ Sbjct: 161 LQVALGHFKSWSVPESFPHVHNYMKTLFSLDSFEKTKTEEKYVISGWA 208 >2YV7-A nrPDB Length = 260 Score = 233 bits (593), Expect = 7e-62, Method: Composition-based stats. Identities = 72/234 (30%), Positives = 115/234 (49%), Gaps = 27/234 (11%) Query: 17 PLIELFVKAGS-DGESIGNCPFSQRLFMILWL----KGVVFSVTTVDLKRKPADLQNLAP 71 P IEL +KA + DG G C F Q FM L+L K + VTTVD+++ P D + Sbjct: 21 PEIELIIKASTIDGRRKGACLFCQEYFMDLYLLAELKTISLKVTTVDMQKPPPDFRTNFE 80 Query: 72 GTHPPFITFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKN 131 THPP + N + KIE + + + P L + E T +++ K + Sbjct: 81 ATHPPILIDNGLAILENEKIERHIMKNI--PGGYNLFVQDKEVATLIENLYVKLKLML-- 136 Query: 132 SRPEANEALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNL 191 + +EA LL L+K++++L++ RFL GD M DC L Sbjct: 137 --VKKDEAKNNALLSHLRKINDHLSA----------------RNTRFLTGDTMCCFDCEL 178 Query: 192 LPKLHIVKVVAKKYRNFDIPKGMTGIWRYLTNAYSRDEFTNTCPSDKEVEIAYS 245 +P+L ++V K + +F+IP +T +WRY+ + Y D FT +CP+D+++ Y Sbjct: 179 MPRLQHIRVAGKYFVDFEIPTHLTALWRYMYHMYQLDAFTQSCPADQDIINHYK 232 >2YV9-A nrPDB Length = 291 Score = 231 bits (588), Expect = 3e-61, Method: Composition-based stats. Identities = 63/272 (23%), Positives = 112/272 (41%), Gaps = 37/272 (13%) Query: 1 MALSMPLNGLKEEDKEPLIELFVKA-GSDGESIGNCPFSQRLFMILWLKGVVFSVTTVDL 59 MA + + + +PL+EL+VKA G D IG F Q +M L+ ++ + + Sbjct: 2 MAEAYQIQSNGDPQSKPLLELYVKASGIDARRIGADLFCQEFWMELY---ALYEIGVARV 58 Query: 60 KRKPAD-----LQNLAPGTHPPFITFNSEVKTDVN------KIEEFLEEVLCPPKYLKLS 108 + K + + G PP + + T + +I +E P L Sbjct: 59 EVKTVNVNSEAFKKNFLGAQPPIMIEEEKELTYTDNREIEGRIFHLAKEFNVP-----LF 113 Query: 109 PKHPESNTAGMDIFAKFSAYIK--------NSRPEANEALERGLLKTLQKLDEYLNSPLP 160 K P + +++ F +++ P E L + ++ E L++ Sbjct: 114 EKDPSAEKRIENLYRNFKLFLRAKVEFDKGKKEPSRVEDLPAQIKVHYNRVCEQLSN--- 170 Query: 161 DEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHIVKVVAKKYRNFDIPKGMTGIWRY 220 ID+ E R+L G+ MT DC L+P+LH ++++ FDIP T +W Y Sbjct: 171 --IDQLLSE----RKSRYLLGNSMTEYDCELMPRLHHIRIIGLSLLGFDIPHNFTHLWAY 224 Query: 221 LTNAYSRDEFTNTCPSDKEVEIAYSDVAKRLT 252 + AY F +CP+D+++ Y + T Sbjct: 225 ILTAYRTAAFIESCPADQDIIHHYKEQMNLFT 256 >5LOL-A nrPDB Length = 215 Score = 227 bits (578), Expect = 4e-60, Method: Composition-based stats. Identities = 57/226 (25%), Positives = 108/226 (47%), Gaps = 24/226 (10%) Query: 19 IELFVKAGSDGESI-GNCPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAPGTHPPF 77 +++ VK + G+CPFSQR+ + L K + + +++ KP +++P P Sbjct: 5 LDICVKVAVGAPDVLGDCPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPV 64 Query: 78 ITFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEAN 137 + + + D + I LEE P PE + G IF F ++K+ +AN Sbjct: 65 VKLDGKWVADSDVIVGLLEEKYPEPSLKTP----PEFASVGSKIFGAFVTFLKSK--DAN 118 Query: 138 EALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHI 197 + E+ L+ L+ L+ +L + + F+ G+++T D +L PKL+ Sbjct: 119 DGSEKALVDELEALENHLKTH----------------SGPFVAGEKITAVDLSLAPKLYH 162 Query: 198 VKVVAKKYRNFDIPKGMTGIWRYLTNAYSRDEFTNTCPSDKEVEIA 243 ++V Y+N+ +P+ +T + Y +SR+ F NT + KE+ +A Sbjct: 163 LEVALGHYKNWSVPESLTSVRNYAKALFSRESFENTK-AKKEIVVA 207 >4QQ7-A nrPDB Length = 207 Score = 186 bits (472), Expect = 8e-48, Method: Composition-based stats. Identities = 43/207 (20%), Positives = 85/207 (41%), Gaps = 18/207 (8%) Query: 34 NCPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAPGTHPPFITFNSEVKTDVNKIEE 93 CPFSQR ++L+ KG+ F + VDL KP D+ + P P + + + N I E Sbjct: 13 TCPFSQRCRLVLFEKGMDFEIRDVDLFNKPEDISVMNPYGQVPILVERDLILYESNIINE 72 Query: 94 FLEEVLCPPKYLKLSP-KHPESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTLQKLD 152 +++E P+ + P + + ++ + ++ E +A E+ K + Sbjct: 73 YIDERFPHPQLMPADPVQRARARLFLLNFEKELFVHVSTLENEKGKAAEKNHEKARLAIR 132 Query: 153 EYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHIVKVVAKKYRNFDIPK 212 + L P F +++ G+E ++ D + P L + + ++ K Sbjct: 133 DRLTQLAP-----------IFVKNKYMLGEEFSMLDVAIAPLLWRL-----DHYGIELSK 176 Query: 213 GMTGIWRYLTNAYSRDEFTNT-CPSDK 238 + +Y +SR + PS+K Sbjct: 177 NAAPLMKYAERIFSRPAYIEALTPSEK 203 >3LFL-A nrPDB Length = 240 Score = 81.0 bits (198), Expect = 4e-16, Method: Composition-based stats. Identities = 31/166 (18%), Positives = 65/166 (39%), Gaps = 14/166 (8%) Query: 35 CPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAPGTHPPFITFN-SEVKTDVNKIEE 93 CPF++R ++L KG+ V ++LK KP P P + + ++ + E Sbjct: 32 CPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCE 91 Query: 94 FLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTLQKLDE 153 +L+E K L P +++F+K + + + N+ GL + +K Sbjct: 92 YLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRK--- 148 Query: 154 YLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHIVK 199 + +E + F G+ +++ D + P ++ Sbjct: 149 ----------EFTKLEVLTNKKTTFFGGNSISMIDYLIWPWFERLE 184 >4PQI-A nrPDB Length = 241 Score = 79.5 bits (194), Expect = 1e-15, Method: Composition-based stats. Identities = 39/216 (18%), Positives = 71/216 (32%), Gaps = 21/216 (9%) Query: 34 NCPFSQRLFMILWLKGVVFSVTTVDL--KRKPADL-QNLAPGTHPPFITFNSEVKTDVNK 90 CPF+QR+++ KG+ + V L + +PA + + P P + N ++ + Sbjct: 40 TCPFAQRVWITRNFKGLQDEIKLVPLILQNRPAWYPEKVYPPNKVPSLEHNGKITGESLD 99 Query: 91 IEEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTLQK 150 + ++LE P L P E KF+ + Sbjct: 100 LIKYLESNFEGPSLLPKDPAKKEFAEELFSYTDKFNGTV------------------YTA 141 Query: 151 LDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHIVKVVAKKYRNFDI 210 L D KF F G E +L D +P + + + + +DI Sbjct: 142 FKGDLAKEAGPAFDHLENALHKFDDGPFFLGKEFSLVDIAYIPFVERLNIFLLEVFKYDI 201 Query: 211 PKGMTGIWRYLTNAYSRDEFTNTCPSDKEVEIAYSD 246 G + ++ + + T KE+ Y Sbjct: 202 TAGRQKLAAWIEEVNKIEAYKQTKTDPKELVEFYKK 237 >2CZ2-A nrPDB Length = 223 Score = 75.6 bits (184), Expect = 2e-14, Method: Composition-based stats. Identities = 31/163 (19%), Positives = 65/163 (39%), Gaps = 14/163 (8%) Query: 38 SQRLFMILWLKGVVFSVTTVDL-----KRKPADLQNLAPGTHPPFITFNSEVKTDVNKIE 92 S R+ + L LKG+ + + ++L ++ + Q L P P + + I Sbjct: 24 SWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSLAIM 83 Query: 93 EFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTLQKLD 152 E+LEE P+ L P+ D+ A ++N E + + + Sbjct: 84 EYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQKVIT 143 Query: 153 EYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKL 195 N+ + ++ + ++ GDE+++AD L+P++ Sbjct: 144 SGFNA---------LEKILQSTAGKYCVGDEVSMADVCLVPQV 177 >3QAG-A nrPDB Length = 239 Score = 72.9 bits (177), Expect = 1e-13, Method: Composition-based stats. Identities = 33/169 (19%), Positives = 60/169 (35%), Gaps = 12/169 (7%) Query: 35 CPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAPGTHPPFI-TFNSEVKTDVNKIEE 93 CP+S R ++L K + V ++L+ KP P H P + T S++ + E Sbjct: 32 CPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQSQLIYESVIACE 91 Query: 94 FLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTLQKLDE 153 +L++ K P +++F+K K E LK + Sbjct: 92 YLDDAYPGRKLFPYDPYERARQKMLLELFSKVPHLTKECLVALRSGRESTNLKAALR--- 148 Query: 154 YLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHIVKVVA 202 + N E +++ F G +++ D L P + V Sbjct: 149 --------QEFSNLEEILEYQNTTFFGGTSISMIDYLLWPWFERLDVYG 189 >1FW1-A nrPDB Length = 216 Score = 71.4 bits (173), Expect = 4e-13, Method: Composition-based stats. Identities = 36/163 (22%), Positives = 63/163 (38%), Gaps = 14/163 (8%) Query: 38 SQRLFMILWLKGVVFSVTTVDL-----KRKPADLQNLAPGTHPPFITFNSEVKTDVNKIE 92 S R+ + L LKG+ + ++L ++ D Q L P P + + I Sbjct: 17 SWRVRIALALKGIDYKTVPINLIKDGGQQFSKDFQALNPMKQVPTLKIDGITIHQSLAII 76 Query: 93 EFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTLQKLD 152 E+LEE P+ L PK S D+ A ++N E L + Sbjct: 77 EYLEETRPTPRLLPQDPKKRASVRMISDLIAGGIQPLQNLSVLKQVGEEMQLTWAQNAIT 136 Query: 153 EYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKL 195 N+ + ++ + + GDE+T+AD L+P++ Sbjct: 137 CGFNA---------LEQILQSTAGIYCVGDEVTMADLCLVPQV 170 >4J2F-A nrPDB Length = 223 Score = 71.0 bits (172), Expect = 4e-13, Method: Composition-based stats. Identities = 36/217 (16%), Positives = 69/217 (31%), Gaps = 22/217 (10%) Query: 35 CPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAP-GTHPPFITFNSEVKTDVNKIEE 93 PFS R+ L LKG+ + DL K L P P + + + I E Sbjct: 13 SPFSCRVIWALKLKGIPYEYVEEDLFNKSPLLLQYNPVHKKIPVLVHGGKPICESTIILE 72 Query: 94 FLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEANEALERGL---LKTLQK 150 +L+E L P + I N E LE+ + L+ L+ Sbjct: 73 YLDETWPENPLLPSDPHERAVARFWVKFIEDKGTAIWNIFRTKGEELEKAVKNCLEVLKT 132 Query: 151 LDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHIVKVVAKKYRNFDI 210 ++E+ + S ++ GD++ + D H + V+ ++ + Sbjct: 133 IEEH---------------AMGVSDDKYFGGDKIGIVDIAFCGIAHWLGVI-EEVAGVKV 176 Query: 211 --PKGMTGIWRYLTNAYSRDEFTNTCPSDKEVEIAYS 245 + + + N P ++ + Sbjct: 177 LESQKFPRLHAWTENFKEAPIIKENLPDRDQMTAFFK 213 >2VO4-A nrPDB Length = 219 Score = 68.7 bits (166), Expect = 2e-12, Method: Composition-based stats. Identities = 37/223 (16%), Positives = 73/223 (32%), Gaps = 25/223 (11%) Query: 35 CPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAP-GTHPPFITFNSEVKTDVNKIEE 93 PF R+ + L KG+ + DL+ K L + P P + N + + + Sbjct: 13 SPFGMRVRIALAEKGIKYEYKEEDLRNKSPLLLQMNPVHKKIPVLIHNGKPICESLIAVQ 72 Query: 94 FLEEVLCP-----PKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTL 148 ++EEV P + I S+ E EA ++ ++ L Sbjct: 73 YIEEVWNDRNPLLPSDPYQRAQTRFWADYVDKKIYDLGRKIWTSKGEEKEAAKKEFIEAL 132 Query: 149 QKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHIVKVVAKKYRNF 208 + L+E L + + GD + D L+P + + + Sbjct: 133 KLLEEQLG------------------DKTYFGGDNLGFVDIALVP-FYTWFKAYETFGTL 173 Query: 209 DIPKGMTGIWRYLTNAYSRDEFTNTCPSDKEVEIAYSDVAKRL 251 +I + ++ + P ++V D+ K+L Sbjct: 174 NIESECPKFIAWAKRCLQKESVAKSLPDQQKVYEFIMDLRKKL 216 >4CHS-A nrPDB Length = 219 Score = 67.9 bits (164), Expect = 4e-12, Method: Composition-based stats. Identities = 39/223 (17%), Positives = 76/223 (34%), Gaps = 25/223 (11%) Query: 35 CPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAP-GTHPPFITFNSEVKTDVNKIEE 93 PF R+ + L KG+ + DL+ K L + P P + N + ++ + Sbjct: 13 SPFGMRVRIALAEKGIEYEYKEEDLRNKSPLLLQMNPVHKKIPVLIHNGKPISESLIAVQ 72 Query: 94 FLEEV-LCPPKYLKLSPKHPESNTAGMDI----FAKFSAYIKNSRPEANEALERGLLKTL 148 ++EEV L P D I S+ E EA ++ ++ L Sbjct: 73 YIEEVWNDRNPLLPSDPYQRAQARFWADYVDIKIHDLGKKIWTSKGEEKEAAKKEFIEAL 132 Query: 149 QKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHIVKVVAKKYRNF 208 + L+E L + + GD + D L+P + V + + + Sbjct: 133 KLLEEQLG------------------DKTYFGGDNIGFVDIALVP-FYTWFKVYETFGSL 173 Query: 209 DIPKGMTGIWRYLTNAYSRDEFTNTCPSDKEVEIAYSDVAKRL 251 +I + ++ + P +V ++ K+L Sbjct: 174 NIENECPRFVAWAKRCLQKESVAKSLPDQHKVYEFVVEIRKKL 216 >5J5N-A nrPDB Length = 231 Score = 67.5 bits (163), Expect = 5e-12, Method: Composition-based stats. Identities = 34/212 (16%), Positives = 70/212 (33%), Gaps = 25/212 (11%) Query: 35 CPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAP-GTHPPFITFNSEVKTDVNKIEE 93 PF R+ + L KGV + + DL K A L + P P + N + + I + Sbjct: 25 SPFGMRVRLALAEKGVKYEYSEEDLWNKSALLLQMNPVNKQIPVLVHNGKPVCESLIIVQ 84 Query: 94 FLEE--VLCPPKYLKLSPKHPES---NTAGMDIFAKFSAYIKNSRPEANEALERGLLKTL 148 +++E P + +S I + E EA ++ + +L Sbjct: 85 YIDEVWKDSAPLLPSDPYQRAQSRFWADFVDKKIYDLGRKIWTKKGEEQEAAKKDFIDSL 144 Query: 149 QKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHIVKVVAKKYRNF 208 + ++ L + + G+ + D L+P + + NF Sbjct: 145 KLMEGELG------------------DKPYFGGETIGYVDIALVP-FYSWFYAYETIGNF 185 Query: 209 DIPKGMTGIWRYLTNAYSRDEFTNTCPSDKEV 240 +I + Y ++ + ++V Sbjct: 186 NIEAECPKMIAYCKRCLQKETVSKALEDPQKV 217 >3WD6-A nrPDB Length = 256 Score = 67.1 bits (162), Expect = 7e-12, Method: Composition-based stats. Identities = 40/206 (19%), Positives = 64/206 (31%), Gaps = 28/206 (13%) Query: 35 CPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAPGTHPP-FITFNSEVKTDVNKIEE 93 CP++QR + L K + + V +DL KP L + P + E Sbjct: 38 CPYAQRTILALNAKQIDYEVVNIDLIDKPEWLTTKSAFAKVPAIEIAEDVTIYESLVTVE 97 Query: 94 FLEEVLCPPKYLKLSPKHP-------ESNTAGMDIFAKFSAYIKNSRPEANEALERGLLK 146 +L+EV L P E++ +F K + E A + L Sbjct: 98 YLDEVYPKRPLLPQDPLKKALDKIIVEASAPIQSLFIKILKFSDTVNEEHVAAYHKAL-- 155 Query: 147 TLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHIVKVVAKKYR 206 + E +K FLDG E AD + P ++ A R Sbjct: 156 ------------------DFIQEQLKNRGTVFLDGSEPGYADYMIWPWFERLRAFAHDER 197 Query: 207 NFDIPKGMTGIWRYLTNAYSRDEFTN 232 P + + Y+ N + Sbjct: 198 VRLEPSKYSLLLEYIDNMLKDSAVSQ 223 >1AW9-A nrPDB Length = 216 Score = 64.0 bits (154), Expect = 5e-11, Method: Composition-based stats. Identities = 39/203 (19%), Positives = 69/203 (33%), Gaps = 15/203 (7%) Query: 40 RLFMILWLKGVVFSVTTVDLK---RKPADLQNLAPGTHPPFITFNSEVKTDVNKIEEFLE 96 R+ +L KG+ F + VDL K D L P P + EV + I ++ Sbjct: 16 RVATVLNEKGLDFEIVPVDLTTGAHKQPDFLALNPFGQIPALVDGDEVLFESRAINRYIA 75 Query: 97 EVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEANEALERGLL---KTLQKLDE 153 + L P + + + + + N+ P + L R LL +D+ Sbjct: 76 SKYAS-EGTDLLPATASAAKLEVWLEVESHHFYPNASPLVFQLLVRPLLGGAPDAAVVDK 134 Query: 154 YLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHIVKVVAKKYRNFDIPKG 213 + + + + ++L GDE TLAD N L + K + Sbjct: 135 HAEQLA----KVLDVYEAHLARNKYLAGDEFTLADANHASYLLYLSKTPK----AGLVAA 186 Query: 214 MTGIWRYLTNAYSRDEFTNTCPS 236 + + +R F T + Sbjct: 187 RPHVKAWWEAIVARPAFQKTVAA 209 >1E6B-A nrPDB Length = 221 Score = 61.3 bits (147), Expect = 4e-10, Method: Composition-based stats. Identities = 39/204 (19%), Positives = 69/204 (33%), Gaps = 17/204 (8%) Query: 40 RLFMILWLKGVVFSVTTVDLKRKPA---DLQNLAPGTHPPFITFNSEVKTDVNKIEEFLE 96 R+ + L LKG+ + V+L + D + + P P + V D I +L+ Sbjct: 22 RVRIALALKGLDYEYIPVNLLKGDQFDSDFKKINPMGTVPALVDGDVVINDSFAIIMYLD 81 Query: 97 EVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTLQKLDEYLN 156 E P L N + S + +P N A+ R + + + ++ Sbjct: 82 EKYPEPPLLPRDLHKRAVN------YQAMSIVLSGIQPHQNLAVIRYIEEKINVEEKTAW 135 Query: 157 SPLPDEIDENSMEDIKFS-TRRFLDGDEMTLADCNLLPKLHIVKVVAKKYRNFDIPKGMT 215 ++E + + + GDE+ LAD L P++H F I Sbjct: 136 VNNAITKGFTALEKLLVNCAGKHATGDEIYLADLFLAPQIH------GAINRFQINMEPY 189 Query: 216 GIWRYLTNAY-SRDEFTNTCPSDK 238 +Y F N P + Sbjct: 190 PTLAKCYESYNELPAFQNALPEKQ 213 >5NR1-A nrPDB Length = 228 Score = 61.0 bits (146), Expect = 5e-10, Method: Composition-based stats. Identities = 42/202 (20%), Positives = 67/202 (33%), Gaps = 14/202 (6%) Query: 35 CPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAPGTHPPFITF----NSEVKTDVNK 90 P S+++ + L K + F V P + +L P PP + + V + Sbjct: 13 DPASRQVRLALGEKRLPFVEMQVRYWEMPPEFTSLNPSGMPPVLVETKHQRNLVICETRA 72 Query: 91 IEEFLEEVLCPPKYLKLSP-KHPESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTLQ 149 I E +EE P L P + E+ KF + +E +E+ LL+ Sbjct: 73 ILEHIEETETEPPLLGRDPAERAEARRLLQWFDRKFDNEVNGFL--LHEKMEKRLLRMGA 130 Query: 150 KLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHIVKVVAKKYRNFD 209 L + TR +L G M+LAD L ++ D Sbjct: 131 PDLAALRQGREALRMHLGYIESLLQTRDWLAGRRMSLADFAAAAHLSVIDYFG------D 184 Query: 210 IP-KGMTGIWRYLTNAYSRDEF 230 +P K + SR F Sbjct: 185 VPWKDFQAAKTWYMKLKSRPCF 206 >4AGS-A nrPDB Length = 471 Score = 59.8 bits (143), Expect = 1e-09, Method: Composition-based stats. Identities = 39/233 (16%), Positives = 76/233 (32%), Gaps = 24/233 (10%) Query: 19 IELFVKAGSDGESIGNCPFSQRLFMILWLKGVVFSVTTVDLKRK-PADLQNLAPGTHPPF 77 ++L+V A CPF R+ ++ K V + V L+ + P + + P P Sbjct: 27 LKLYVSA--------TCPFCHRVEIVAREKQVSYDRVAVGLREEMPQWYKQINPRETVPT 78 Query: 78 ITF---NSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRP 134 + + + I ++L+ P L A+ +I Sbjct: 79 LEVGNADKRFMFESMLIAQYLDNSGAPAG--ALMGSSAAQRHQIEFFLAQVGDFI----- 131 Query: 135 EANEALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPK 194 GLL+ ++ + + + + +T + E T+AD L+P Sbjct: 132 ----GAAHGLLRDPLSGEKR-KAMDDNAAYVDGLLAANQTTGPYYCDGEFTMADVALVPF 186 Query: 195 LHIVKVVAKKYRNFDIPKGMTGIWRYLTNAYSRDEFTNTCPSDKEVEIAYSDV 247 L +K Y +D+ + A R T P+ + Y + Sbjct: 187 LVRLKPALMYYAGYDVFCKAPRMKALWAAAAQRASVRETSPTAAQCIENYRHL 239 Score = 55.6 bits (132), Expect = 2e-08, Method: Composition-based stats. Identities = 33/201 (16%), Positives = 62/201 (30%), Gaps = 21/201 (10%) Query: 35 CPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAPGTHPPFI-TFNSEVKTDVNKIEE 93 CPF R + L+ + V L +P + + P P + T + E + I + Sbjct: 261 CPFVDRARLASELRKFQMHIVEVPLHPQPEWYKYINPRDTVPALFTPSGEAVHESQLIVQ 320 Query: 94 FLEEVLCPPKYLKLSPKHPESNTAGMDIFAK----FSAYIKNSRPEANEALERGLLKTLQ 149 +++ K L P+ + F + F + + E + L Sbjct: 321 YID--CVATKGSALVPRGDAEKEYEVGFFVENAGYFVGGLMSWIIRGGEDAKAELQWAAG 378 Query: 150 KLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHIVKVVAKKYR-NF 208 +L++ L F F G M D +LP L K ++ + Sbjct: 379 ELEQQLAKH-------------PFGEGPFFGGKRMNAGDVAILPFLVRAKAFMPEFSGGY 425 Query: 209 DIPKGMTGIWRYLTNAYSRDE 229 D+ + + E Sbjct: 426 DLFAHFPLLNGLAEAGMATPE 446 >3UBL-A nrPDB Length = 242 Score = 59.4 bits (142), Expect = 2e-09, Method: Composition-based stats. Identities = 36/222 (16%), Positives = 74/222 (33%), Gaps = 12/222 (5%) Query: 28 DGESIGNCPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAPGTHPPFITFNSEVKTD 87 G SI N + ++ + + KG+ + + ++ D ++P P + + + + Sbjct: 7 HGASISN--YVNKVKLGILEKGLEYEQIRIAPSQE-EDFLKISPMGKIPVLEMDGKFIFE 63 Query: 88 VNKIEEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKT 147 I EFL+ + P+ KL P+ P +I Y+ R L Sbjct: 64 SGAILEFLDTIF--PQTPKLIPEDPWEAARVREISTIIETYLDIP-------ARRIYLPA 114 Query: 148 LQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHIVKVVAKKYRN 207 + E + + ++ G+ TLADC+ L ++ + + Sbjct: 115 AKVSPEIVEEVHSTLVKGIKALQRVVRFSPYIAGNVFTLADCSGFAHLSVLDEELRPFYP 174 Query: 208 FDIPKGMTGIWRYLTNAYSRDEFTNTCPSDKEVEIAYSDVAK 249 + P + W+ DK++ AK Sbjct: 175 NNHPLDLLNGWKEYFVFMKTKAGPALVEKDKQILKKILARAK 216 >2JL4-A nrPDB Length = 213 Score = 58.7 bits (140), Expect = 3e-09, Method: Composition-based stats. Identities = 49/214 (22%), Positives = 76/214 (35%), Gaps = 30/214 (14%) Query: 38 SQRLFMILWLKGVVFSVTTVDLKRK---PADLQNLAPGTHPPFITFNSEVKTDVNKIEEF 94 S RL + L LKGV + V L ++ + L P P + ++V I E+ Sbjct: 13 SHRLRIALNLKGVPYEYLAVHLGKEEHLKDAFKALNPQQLVPALDTGAQVLIQSPAIIEW 72 Query: 95 LEEVLCPPKYLKLSPKHPE-----SNTAGMDIFA----KFSAYIKNSRPEANEALERGLL 145 LEE P L + + G DI + Y++ A+EA Sbjct: 73 LEEQYPTPALLPADADGRQRVRALAAIVGCDIHPINNRRILEYLR-KTFGADEA------ 125 Query: 146 KTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHIVKVVAKKY 205 + S D + D K R+ GD TLADC L+P++ + Sbjct: 126 -AINAWCGTWISAGFDAYEALLAVDPK--RGRYSFGDTPTLADCYLVPQV-------ESA 175 Query: 206 RNFDIPKGMTGIWRYLTNAY-SRDEFTNTCPSDK 238 R F + + R + A D F P+ + Sbjct: 176 RRFQVDLTPYPLIRAVDAACGELDAFRRAAPAAQ 209 >3IBH-A nrPDB Length = 233 Score = 56.0 bits (133), Expect = 1e-08, Method: Composition-based stats. Identities = 35/210 (16%), Positives = 71/210 (33%), Gaps = 26/210 (12%) Query: 36 PFSQRLFMILWLKGVVFSVTTVDLK------RKPADLQNLAPGTHPPFITFNSEVKTDVN 89 P+ R+ + L K ++ SV V + +KP L GT P + + + Sbjct: 28 PYPARVRIALAEKNMLSSVQFVRINLWKGEHKKPEFLAKNYSGTVPVLELDDGTLIAECT 87 Query: 90 KIEEFLEEVLCPPKYLKLSPKHPES-----NTAGMDIFAKFSAYIKNSRPEANEALE--R 142 I E+++ + P +P A +++ S Y ++ P +E + Sbjct: 88 AITEYIDALDGTPTLTGKTPLEKGVIHMMNKRAELELLDPVSVYFHHATPGLGPEVELYQ 147 Query: 143 GLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHIVKVVA 202 L++ D+ L D E R ++ GD ++AD ++ L + Sbjct: 148 NKEWGLRQRDKAL--HGMHYFDTVLRE------RPYVAGDSFSMADITVIAGL-----IF 194 Query: 203 KKYRNFDIPKGMTGIWRYLTNAYSRDEFTN 232 +P+ + + R Sbjct: 195 AAIVKLQVPEECEALRAWYKRMQQRPSVKK 224 >3R2Q-A nrPDB Length = 202 Score = 53.6 bits (127), Expect = 8e-08, Method: Composition-based stats. Identities = 36/207 (17%), Positives = 68/207 (32%), Gaps = 20/207 (9%) Query: 34 NCPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAPGTHPPFI-TFNSEVKTDVNKIE 92 PF ++L ++L KG+ F + P P + T E D I Sbjct: 8 TSPFVRKLSILLLEKGITFEFINELPYNADNGVAQFNPLGKVPVLVTEEGECWFDSPIIA 67 Query: 93 EFLEEVLCPPKYLKLSP----KHPESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTL 148 E++E + P L P + + I ++ A + E LL+ Sbjct: 68 EYIELMNVAPAMLPRDPLESLRVRKIEALADGIMDAGLVSVREQARPAAQQSEDELLRQR 127 Query: 149 QKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHIVKVVAKKYRNF 208 +K++ L+ +D D + C + L+ +V + Sbjct: 128 EKINRSLDVLEGYLVDGTLKTDTVNLATIAIA--------CAVG-YLNFRRVAP----GW 174 Query: 209 DIPKGMTGIWRYLTNAYSRDEFTNTCP 235 + + + + N +SR+ F T P Sbjct: 175 CV--DRPHLVKLVENLFSRESFARTEP 199 >5EY6-A nrPDB Length = 217 Score = 52.9 bits (125), Expect = 1e-07, Method: Composition-based stats. Identities = 34/167 (20%), Positives = 56/167 (33%), Gaps = 23/167 (13%) Query: 40 RLFMILWLKGVVFSVTTVDLKR---KPADLQNLAPGTHPPFITFNSEVKTDVNKIEEFLE 96 R+ + L K V F + VD+ + K D + P P S + I ++ Sbjct: 17 RVLVTLLEKDVPFQIIPVDMSKGEHKKPDYLKIQPFGQVPAFQDESISLFESRSICRYVC 76 Query: 97 EVLCPPKYLKLSPKHP-ESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTLQKLDEYL 155 E L +P E + + A+ ++ G L + Sbjct: 77 EKYADRGDKGLYGTNPLERASIDQWVEAEGQSF----------GPSSGALVFQLAFAPRM 126 Query: 156 NSPLPDEIDENSME---------DIKFSTRRFLDGDEMTLADCNLLP 193 N P + + + E + + RFL GDE T AD + LP Sbjct: 127 NIPQDQGVIKQNEEKLGKVLDIYEQRLGESRFLAGDEFTFADLSHLP 173 >5F07-A nrPDB Length = 213 Score = 52.1 bits (123), Expect = 2e-07, Method: Composition-based stats. Identities = 35/177 (19%), Positives = 62/177 (35%), Gaps = 24/177 (13%) Query: 29 GESIGNCPFSQRLFMILWLKGVVFSVTTVDL---KRKPADLQNLAPGTHPPFITFNSEVK 85 G ++ CP QR+ L KGV F + VDL ++K + P P + Sbjct: 6 GPAVAVCP--QRVMACLLEKGVEFDLVHVDLDSGEQKLPEFLLKQPFGQVPVVEDGDFKL 63 Query: 86 TDVNKIEEFLEEVLCP--PKYLKLSPKHPESNTAGMDIF-AKFSAYIKNSR------PEA 136 + I + P L + + ++I F+ + N P Sbjct: 64 FESRAIIRYYAAKYEDRGPNLLGNTLEEKALVDQWLEIEAHNFNDLVFNIVFQVVILPRI 123 Query: 137 NEALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLP 193 + + L++T + + + + S ++L GD TLAD + LP Sbjct: 124 GQQGDSELVRTYE----------EKLEKVLDVYEKRLSKSKYLAGDSFTLADLSHLP 170 >5F06-A nrPDB Length = 216 Score = 51.7 bits (122), Expect = 3e-07, Method: Composition-based stats. Identities = 37/205 (18%), Positives = 75/205 (36%), Gaps = 25/205 (12%) Query: 40 RLFMILWLKGVVFSVTTVDL---KRKPADLQNLAPGTHPPFITFNSEVKTDVNKIEEFLE 96 R+ L K + F + VDL + K P P + + + I ++ Sbjct: 15 RVLTCLHEKNLDFELVPVDLFAGEHKQPPFLAKNPFGQIPALEEDDLTLFESRAITSYIA 74 Query: 97 EVLCPPKYLKLSPKH-PESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTLQKLDEYL 155 E Y + ++ E+ + ++ + ++ N P + + ++ L+ Sbjct: 75 EKFKGTGYDLIRHENLKEAASV--KVWTEVESHRYN--PAIAPIVFQFMVAPLRG----- 125 Query: 156 NSPLPDEIDENSME--------DIKFSTRRFLDGDEMTLADCNLLPKLHIVKVVAKKYRN 207 NSP ID+N + + K S+ ++L GD +LAD + LP + + K Sbjct: 126 NSPDQTIIDDNVEKLGKVLDIYEAKLSSTKYLAGDFYSLADLHHLPYTYYL----MKTPA 181 Query: 208 FDIPKGMTGIWRYLTNAYSRDEFTN 232 + + + + SR F Sbjct: 182 ASVVNERPHVKAWWEDISSRPAFKK 206 >4IGJ-A nrPDB Length = 242 Score = 51.3 bits (121), Expect = 4e-07, Method: Composition-based stats. Identities = 39/207 (18%), Positives = 68/207 (32%), Gaps = 21/207 (10%) Query: 40 RLFMILWLKGVVFSVTTVDLKRKPAD---LQNLAPGTHPPFIT----FNSEVKTDVNKIE 92 R+ + L LKG+ + VDL + Q P + P + + + I Sbjct: 38 RVRLGLALKGLAYEYRAVDLLAQEQFQAAHQARNPMSQVPVLEVEEDGRTHLLVQSMAIL 97 Query: 93 EFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKN-SRPEANEALERGLLKTLQKL 151 E+LEE P L G + ++ + ++P N + R L + + Sbjct: 98 EWLEERHPEPALLPPD-------LWGRARVRALAEHVNSGTQPMQNALVLRMLREKVPGW 150 Query: 152 DEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHIVKVVAKKYRNFDIP 211 D ++ RF GD TLADC L+P+L+ + Sbjct: 151 DREWARFFIARGLAALETAVRDGAGRFSHGDAPTLADCYLVPQLYNARRFGLDL------ 204 Query: 212 KGMTGIWRYLTNAYSRDEFTNTCPSDK 238 + + R + F P + Sbjct: 205 EPYPTLRRVDEACAALAPFQAAHPDRQ 231 >1GWC-A nrPDB Length = 230 Score = 50.6 bits (119), Expect = 6e-07, Method: Composition-based stats. Identities = 27/141 (19%), Positives = 49/141 (34%), Gaps = 10/141 (7%) Query: 26 GSDGESIGN--CPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAP-GTHPPFITFNS 82 G D + +G PF R+ + L LKG+ + DL +K L P P + N Sbjct: 4 GDDLKLLGAWPSPFVTRVKLALALKGLSYEDVEEDLYKKSELLLKSNPVHKKIPVLIHNG 63 Query: 83 EVKTDVNKIEEFLEEVLCP--PKYLKLSPKHPESNT-----AGMDIFAKFSAYIKNSRPE 135 + I ++++EV P L P + A + +++ E Sbjct: 64 APVCESMIILQYIDEVFASTGPSLLPADPYERAIARFWVAYVDDKLVAPWRQWLRGKTEE 123 Query: 136 ANEALERGLLKTLQKLDEYLN 156 ++ + L+ L Sbjct: 124 EKSEGKKQAFAAVGVLEGALR 144 >4RI7-A nrPDB Length = 215 Score = 50.6 bits (119), Expect = 7e-07, Method: Composition-based stats. Identities = 35/201 (17%), Positives = 65/201 (32%), Gaps = 9/201 (4%) Query: 35 CPFSQRLFMILWLKGVVFSVTTVDLKR---KPADLQNLAPGTHPPFITFNSEVKTDVNKI 91 C R+ L K V F + +DL + K + + P P S + I Sbjct: 13 CTAVSRVLATLIEKDVPFHLIPIDLSKGEQKKPEYLKIQPFGQVPAFKDESITLFESRAI 72 Query: 92 EEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTLQKL 151 ++ + L S +I + P + + + L ++ Sbjct: 73 CRYICDKYADKGNKSLYGTDILSK---ANIDQWVETDGQTFGPPSGDLVHDLLFSSVPVD 129 Query: 152 DEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHIVKVVAKKYRNFDIP 211 + + + + + K RFL GDE + AD + LP + K F Sbjct: 130 EALIKKNVDKLAKVLDIYEQKLGQTRFLAGDEFSFADLSHLPNGDYLVNSTDKGYLFTSR 189 Query: 212 KGMTGIWRYLTNAYSRDEFTN 232 K + W ++N R+ + Sbjct: 190 KNVNRWWTEISN---RESWKK 207 >1OYJ-A nrPDB Length = 231 Score = 50.2 bits (118), Expect = 9e-07, Method: Composition-based stats. Identities = 18/76 (23%), Positives = 28/76 (36%), Gaps = 3/76 (3%) Query: 35 CPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAP-GTHPPFITFNSEVKTDVNKIEE 93 PF QR + + KG+ F DL K L P P + ++ I + Sbjct: 15 SPFGQRCRIAMAEKGLEFEYREEDLGNKSDLLLRSNPVHRKIPVLLHAGRPVSESLVILQ 74 Query: 94 FLEEVLCPPKYLKLSP 109 +L++ P L P Sbjct: 75 YLDDAF--PGTPHLLP 88 >1PN9-A nrPDB Length = 209 Score = 49.8 bits (117), Expect = 1e-06, Method: Composition-based stats. Identities = 36/193 (18%), Positives = 68/193 (35%), Gaps = 39/193 (20%) Query: 33 GNCPFSQRLFMILWLKGVVFSVTTVDLKR----KPADLQNLAPGTHPPFITFNSEVKTDV 88 G+ P + + M GV ++ DL + KP L P P + N + Sbjct: 8 GSAP-CRAVQMTAAAVGVELNLKLTDLMKGEHMKPE-FLKLNPQHCIPTLVDNGFALWES 65 Query: 89 NKIEEFLEEVLCPPKYLKLSPKHPESNTAGMD--------IFAKFSAY----IKNSRPEA 136 I+ +L E KL PK P+ ++ +F+ Y I +P A Sbjct: 66 RAIQIYLAEKYGKDD--KLYPKDPQKRAVVNQRLYFDMGTLYQRFADYHYPQIFAKQP-A 122 Query: 137 NEALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLH 196 N E+ + + L+ +L + + G+++T+AD +L + Sbjct: 123 NPENEKKMKDAVGFLNTFLEG------------------QEYAAGNDLTIADLSLAATIA 164 Query: 197 IVKVVAKKYRNFD 209 +V + + Sbjct: 165 TYEVAGFDFAPYP 177 >3LG6-A nrPDB Length = 235 Score = 49.4 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 41/196 (20%), Positives = 66/196 (33%), Gaps = 31/196 (15%) Query: 38 SQRLFMILWLKGVVFSVTTVDL---KRKPADLQNLAPGTHPPFITFN-----------SE 83 S RL + LK + ++ V+L ++ ++L P P + + S Sbjct: 21 SGRLRIAFHLKSIPYTRHPVNLLKGEQHSDTYKSLNPTNTVPLLVVSNINNTVSPSSASF 80 Query: 84 VKTDVNKIEEFLEEVLCPPKYLKLSPKHPESNTA----GMDIFAKFSAYIKNSRPEANEA 139 E+LEE L L P A +I A + Sbjct: 81 SIGQSLAALEYLEEALPTNARPLLPPISNPVARAHVRTICNIIAC----------DVQPV 130 Query: 140 LERGLLKTLQKLDEYLNSPLPDEIDE---NSMEDIKFSTRRFLDGDEMTLADCNLLPKLH 196 + K ++ LD D + + ++ S RF GDE+TLAD L+P + Sbjct: 131 TNLKIQKKVKALDGDPTVWSRDLATQGFGAVEKLLELSAGRFCVGDEITLADVCLVPAVW 190 Query: 197 IVKVVAKKYRNFDIPK 212 + V F I K Sbjct: 191 AAERVGMDLARFPITK 206 >4MK3-A nrPDB Length = 226 Score = 49.4 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 29/208 (13%), Positives = 71/208 (34%), Gaps = 20/208 (9%) Query: 34 NCPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAPGTHPPFIT-FNSEVKTDVNKIE 92 P+++++ ++L K + + + ++ + P P + + D I Sbjct: 30 TSPYARKVRVVLAEKKIDYEMIEENVWSPDTTIGRFNPLGKVPCLVMEDGGAVFDSRVIA 89 Query: 93 EFLEEVLCPPKY-LKLSPKHPESN----TAGMDIFAKFSAYIKNSRPEANEALERGLLKT 147 E+ + + + + S + E A + A A ++ ++ + +E E + + Sbjct: 90 EYADTLSPVSRLIPQGSRERLEVRCWEALADGLLDAALLARLEVTQRKESERSESWVQRQ 149 Query: 148 LQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHIVKVVAKKYRN 207 K+D L + D+ + G TLAD + L + ++ + Sbjct: 150 RSKIDAALTAMSTGLADKT-----------WCTGTHYTLADVAVGCALAYLDF---RFPD 195 Query: 208 FDIPKGMTGIWRYLTNAYSRDEFTNTCP 235 + + R F +T P Sbjct: 196 IAWRDRHPNLVAFQEKIEKRQSFIDTEP 223 >3BBY-A nrPDB Length = 215 Score = 49.0 bits (115), Expect = 2e-06, Method: Composition-based stats. Identities = 35/204 (17%), Positives = 75/204 (36%), Gaps = 27/204 (13%) Query: 35 CPFSQRLFMILWLKGVVFSVTTVDLKR----KPADLQNLAPGTHPPFITFNSEVKTDVNK 90 P+ ++ L KG+ F + T+DL +P Q P + + ++ + Sbjct: 17 SPYVLSAWVALQEKGLSFHIKTIDLDSGEHLQPTW-QGYGQTRRVPLLQIDDFELSESSA 75 Query: 91 IEEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTLQK 150 I E+LE+ PP + ++ P E+ I A++++ E ++ K Sbjct: 76 IAEYLEDRFAPPTWERIYPLDLENRARARQI----QAWLRSDLMPIREERPTDVVFAGAK 131 Query: 151 LDEYLNSPLPDEIDENSMEDIKFSTRRFLDGD-----EMTLADCNLLPKLHIVKVVAKKY 205 +PL E ++ + + + G E +AD +L ++ + Sbjct: 132 -----KAPLTAEGKASAEKLFAMAEHLLVLGQPNLFGEWCIADTDLALMINRLV-----L 181 Query: 206 RNFDIPKGMTGIWRYLTNAYSRDE 229 ++P+ + Y T + R Sbjct: 182 HGDEVPERLV---DYATFQWQRAS 202 >3RBT-A nrPDB Length = 246 Score = 48.6 bits (114), Expect = 2e-06, Method: Composition-based stats. Identities = 28/176 (15%), Positives = 58/176 (32%), Gaps = 29/176 (16%) Query: 36 PFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAPGTHPPFITF----NSEVKTDVNKI 91 P+ R+ ++L K + + V +D R P + P P + + I Sbjct: 36 PYGHRVLLVLEAKRIKYEVYRLDPLRLPEWFRAKNPRLKIPVLEIPTDQGDRFLFESVVI 95 Query: 92 EEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTLQKL 151 ++L+E P Y+K E + +L+ Sbjct: 96 CDYLDEKYTRHTLHSHDP------------------YVKAQDRLLIERFNELIKGSLECF 137 Query: 152 DEYLNSPLPDEIDENSMEDIKFSTRR---FLDGDEMTLADCNLLP---KLHIVKVV 201 D + ++I + K T R + G+ + D + P +L++++ V Sbjct: 138 DTNF-AFGSEQIIQTLEIFEKELTNRGTNYFGGNRPGMLDYMVWPWVERLYLLRCV 192 >6F05-A nrPDB Length = 215 Score = 48.6 bits (114), Expect = 2e-06, Method: Composition-based stats. Identities = 38/208 (18%), Positives = 69/208 (33%), Gaps = 27/208 (12%) Query: 39 QRLFMILWLKGVVFSVTTVDL---KRKPADLQNLAPGTHPPFITFNSEVKTDVNKIEEFL 95 +R + L KGV F VDL + K L P P + + + ++ Sbjct: 14 KRALVTLIEKGVAFETIPVDLMKGEHKQPAYLALQPFGTVPAVVDGDYKIFESRAVMRYV 73 Query: 96 EEVLCP--PKYLKLSPKHPESNTAGMDIFA--------KFSAYIKNSRPEANEALERGLL 145 E P L + + +D+ A + +I + + E+ + Sbjct: 74 AEKYRSQGPDLLGKTVEDRGQVEQWLDVEATTYHPPLLNLTLHIMFASVMGFPSDEKLIK 133 Query: 146 KTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHIVKVVAKKY 205 ++ +KL L+ S ++L GD ++LAD LP + K Sbjct: 134 ESEEKLAGVLDVYEAH-----------LSKSKYLAGDFVSLADLAHLPFTDYLVGPIGKA 182 Query: 206 RNFDIPKGMTGIWRYLTNAYSRDEFTNT 233 K ++ W + SR + T Sbjct: 183 YMIKDRKHVSAWW---DDISSRPAWKET 207 >2PMT-A nrPDB Length = 203 Score = 48.6 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 41/207 (19%), Positives = 72/207 (34%), Gaps = 36/207 (17%) Query: 33 GNCPFSQRLFMILWLKGVVFSVTTVDLKRKP----ADLQNLAPGTHPPFI-TFNSEVKTD 87 G+C S + +L G+ FS+ +DL+ K D + P P + N ++ T+ Sbjct: 8 GSCSLSPHI--VLRETGLDFSIERIDLRTKKTESGKDFLAINPKGQVPVLQLDNGDILTE 65 Query: 88 VNKIEEFLEEVLC------PPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEANEALE 141 I ++L ++ PPK L+ + N ++ +S + PE+ Sbjct: 66 GVAIVQYLADLKPDRNLIAPPKALERYHQIEWLNFLASEVHKGYSPLFSSDTPES----- 120 Query: 142 RGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHIVKVV 201 L + L S D S ++ + GD T+AD L V Sbjct: 121 -----YLPVVKNKLKSKFVYIND-------VLSKQKCVCGDHFTVADAYLFTLSQWAPHV 168 Query: 202 AKKYRNFDIPKGMTGIWRYLTNAYSRD 228 A ++ + YL R Sbjct: 169 ALDL------TDLSHLQDYLARIAQRP 189 >1JLV-A nrPDB Length = 209 Score = 47.9 bits (112), Expect = 4e-06, Method: Composition-based stats. Identities = 34/193 (17%), Positives = 65/193 (33%), Gaps = 39/193 (20%) Query: 33 GNCPFSQRLFMILWLKGVVFSVTTVDL----KRKPADLQNLAPGTHPPFITFNSEVKTDV 88 G+ P + + M GV ++ +L KP + P P + N + Sbjct: 8 GSAP-CRAVQMTAAAVGVELNLKLTNLMAGEHMKPE-FLKINPQHCIPTLVDNGFALWES 65 Query: 89 NKIEEFLEEVLCPPKYLKLSPKHPESNTAGMD--------IFAKFSAY----IKNSRPEA 136 I +L E KL PK P+ ++ +F+ Y I +P Sbjct: 66 RAICTYLAEKYGKDD--KLYPKDPQKRAVVNQRLYFDMGTLYQRFADYYYPQIFAKQPAN 123 Query: 137 NEALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLH 196 E E+ + + L+ +L+ +++ GD +T+AD +L + Sbjct: 124 AEN-EKKMKDAVDFLNTFLDGH------------------KYVAGDSLTIADLTVLATVS 164 Query: 197 IVKVVAKKYRNFD 209 V + + Sbjct: 165 TYDVAGFELAKYP 177 >5F05-A nrPDB Length = 212 Score = 47.9 bits (112), Expect = 5e-06, Method: Composition-based stats. Identities = 31/166 (18%), Positives = 61/166 (36%), Gaps = 11/166 (6%) Query: 39 QRLFMILWLKGVVFSVTTVDL---KRKPADLQNLAPGTHPPFITFNSEVKTDVNKIEEFL 95 QR+ L+ K V F + V+L + K +L P P + I +++ Sbjct: 15 QRVLATLYEKEVEFELVNVNLGAGEHKQEPHISLNPFGQVPAAVDGDLKLFESRAISQYV 74 Query: 96 EEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTLQKL--DE 153 K +L T + + + P A++ + + K + L D Sbjct: 75 AHQYAS-KGTQLGAAGNGYATILVWQEVESHQF----DPSASKLVWEQVFKPVFGLPTDA 129 Query: 154 YLNSPLPDEIDE-NSMEDIKFSTRRFLDGDEMTLADCNLLPKLHIV 198 L + + + + + + S ++L D TLAD + LP + + Sbjct: 130 ALVAETEVTLGKVLDVYEARLSQSKYLASDSFTLADLHHLPNIQAL 175 >3MAK-A nrPDB Length = 209 Score = 47.5 bits (111), Expect = 6e-06, Method: Composition-based stats. Identities = 39/204 (19%), Positives = 69/204 (33%), Gaps = 37/204 (18%) Query: 33 GNCPFSQRLFMILWLKGVVFSVTTVDLKR----KPADLQNLAPGTHPPFITFNSEVKTDV 88 G+ P + + M GV + ++L+ KP + P P + N + Sbjct: 9 GSSP-CRSVIMTAKAVGVELNKKLLNLQAGEHLKPE-FLKINPQHTIPTLVDNGFALWES 66 Query: 89 NKIEEFLEEVLCPPKYLKLSPKHPESNTAGMD--------IFAKFSAYIKNSRPEANEAL 140 I+ +L E L PK P+ ++ F+ Y A Sbjct: 67 RAIQVYLVEKYGKTD--SLYPKCPKKRAVINQRLYFDMGTLYQSFANYYYPQVFAKAPAD 124 Query: 141 ERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHIVKV 200 K ++ E+LN+ L + + GD +T+AD L+ + +V Sbjct: 125 PEAFKK-IEAAFEFLNTFLEGQD--------------YAAGDSLTVADIALVATVSTFEV 169 Query: 201 VAKKYRNFDIPKGMTGIWRYLTNA 224 F+I K + R+ NA Sbjct: 170 A-----KFEISK-YANVNRWYENA 187 >5ZWP-A nrPDB Length = 208 Score = 46.3 bits (108), Expect = 1e-05, Method: Composition-based stats. Identities = 34/195 (17%), Positives = 62/195 (31%), Gaps = 42/195 (21%) Query: 33 GNCPFSQRLFMILWLKGVVFSVTTVDLKR----KPADLQNLAPGTHPPFITFNSEVKTDV 88 G+ P + + M G+ + ++L+ KP + P P + + Sbjct: 8 GSAP-CRSVLMTAKALGIELNKKLLNLQAGEHLKPE-FLKINPQHTIPTLVDGDFALWES 65 Query: 89 NKIEEFLEEVLCPPKYLKLSPKHPESNTAGMD--------IFAKFSAYIKNS---RPEAN 137 I +L E L PK P+ ++ F+ Y + A+ Sbjct: 66 RAIMVYLVEKYGKTD--SLFPKCPKKRAVINQRLYFDMGTLYKSFADYYYPQIFAKAPAD 123 Query: 138 EALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHI 197 L + + L+ +L + GD +T+AD LL + Sbjct: 124 PELFKKIETAFDFLNTFLKGH------------------EYAAGDSLTVADLALLASVST 165 Query: 198 VKVVAKKYRNFDIPK 212 +V +FDI K Sbjct: 166 FEVA-----SFDISK 175 >3M1G-A nrPDB Length = 362 Score = 45.9 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 44/242 (18%), Positives = 83/242 (34%), Gaps = 39/242 (16%) Query: 34 NCPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQ----NLAPGTHPPFITFNSEVKTDVN 89 CP++ R + L G+ +V ++ L D++ +L P P + N Sbjct: 69 ACPWAHRTVITRRLLGLE-NVISLGLTGPTHDVRSWTFDLDPNHLDPVLQIPRLQDAYFN 127 Query: 90 KIEEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAK----FSAYIKNSRPEANEALERGLL 145 + ++ P + S + + F+ K E L L Sbjct: 128 RFPDY------PRGITVPALVEESSKKVVTNDYPSITIDFNLEWKQFHREGAPNLYPAEL 181 Query: 146 KT-----LQKLDEYLNSPLPDEIDENSME----------------DIKFSTRRFLDGDEM 184 + ++++ +N+ + S E + + STRR+L GD + Sbjct: 182 REEMAPVMKRIFTEVNNGVYRTGFAGSQEAHNEAYKRLWVALDWLEDRLSTRRYLMGDHI 241 Query: 185 TLADCNLLPKLHIVK-VVAKKYR-NFDIPKGMTGIWRYLTNAYSRDEFTNTCPSDKEVEI 242 T AD L P L V ++ + M +W YL + + F +T E++ Sbjct: 242 TEADIRLYPTLVRFDAVYHGHFKCGRNKITEMPNLWGYLRDLFQTPGFGDTT-DFTEIKQ 300 Query: 243 AY 244 Y Sbjct: 301 HY 302 >3NIV-A nrPDB Length = 222 Score = 45.9 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 33/166 (19%), Positives = 62/166 (37%), Gaps = 10/166 (6%) Query: 38 SQRLFMILWLKGVVFS---VTTVDLKRKPADLQ--NLAPGTHPPFITFNSEVKTDVNKIE 92 R+ + L LK + + V V+ + LQ + P P + N ++ + I Sbjct: 14 CYRVRIALNLKKIAYEKIEVHLVNNGGEQHSLQYHQINPQELVPSLDINGQILSQSMAII 73 Query: 93 EFLEEVLCPPKYLKLSPKHP--ESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTLQK 150 ++LEE+ + L PK P ++ M + + N+ N E+ Q Sbjct: 74 DYLEEIHPE---MPLLPKDPFMKATLKSMALIVACDMHPLNNLRVLNRLKEQFNANEEQV 130 Query: 151 LDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLH 196 L+ Y + + G E+ LAD L+P+++ Sbjct: 131 LEWYHHWLKTGFDAFEEKLGALERDKPVCFGSEVGLADVCLIPQVY 176 >5F0G-A nrPDB Length = 215 Score = 45.9 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 30/188 (15%), Positives = 63/188 (33%), Gaps = 38/188 (20%) Query: 38 SQRLFMILWLKGVVFSVTTVDL----KRKPADLQNLAPGTHPPFITFNSEVKTDVNKIEE 93 + + M+ G+ + ++ + KP L P P + N + I Sbjct: 12 CRTVIMVAKALGLELNKKLLNTMEGEQLKPE-FVKLNPQHTIPTLVDNGFSIWESRAIAV 70 Query: 94 FLEEVLCPPKYLKLSPKHPESNTAGMD--------IFAKFSAY----IKNSRPEANEALE 141 +L E Y L P P+ ++ F+ Y + +P ++E L Sbjct: 71 YLVEKYGKDDY--LLPNDPKKRAVINQRLYFDMGTLYESFAKYYYPLFRTGKPGSDEDL- 127 Query: 142 RGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHIVKVV 201 + + LD +L + ++ GD++T+AD +L + +V Sbjct: 128 KRIETAFGFLDTFLEG------------------QEYVAGDQLTVADIAILSTVSTFEVS 169 Query: 202 AKKYRNFD 209 + + Sbjct: 170 EFDFSKYS 177 >1F2E-A nrPDB Length = 201 Score = 44.8 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 32/207 (15%), Positives = 54/207 (26%), Gaps = 36/207 (17%) Query: 43 MILWLKGVVFSVTTVDLKRKP----ADLQNLAPGTHPPFITFN-SEVKTDVNKIEEFLEE 97 + L G F VDL + D + P P +T + E T+ I ++ + Sbjct: 16 IALRETGADFEAVKVDLAVRKTEAGEDFLTVNPSGKVPALTLDSGETLTENPAILLYIAD 75 Query: 98 VLCPPKYLKLSPKHPESNT------AGMDIFAKFS-AYIKNSRPEANEALERGLLKTLQK 150 G + F + + EA A + L Sbjct: 76 QNPASGLAPAEGSLDRYRLLSRLSFLGSEFHKAFVPLFAPATSDEAKAAAAESVKNHLAA 135 Query: 151 LDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHIVKVVAKKYRNFDI 210 LD+ L R G+ ++AD L V + Y D+ Sbjct: 136 LDKELAG------------------RDHYAGNAFSVADIYL-----YVMLGWPAYVGIDM 172 Query: 211 PKGMTGIWRYLTNAYSRDEFTNTCPSD 237 + Y R ++ Sbjct: 173 -AAYPALGAYAGKIAQRPAVGAALKAE 198 >6JWK-A nrPDB Length = 222 Score = 44.4 bits (103), Expect = 5e-05, Method: Composition-based stats. Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 4/83 (4%) Query: 34 NCPFSQRLFMILWLKGVVFSVTTVDLKR----KPADLQNLAPGTHPPFITFNSEVKTDVN 89 N S R+ + L LKG+ + V V+L++ +PAD Q G P + + + Sbjct: 8 NSSTSYRVRIALALKGLDYQVVPVNLRQGEQLRPADRQRNPMGALPTLVDADGRRFSQSL 67 Query: 90 KIEEFLEEVLCPPKYLKLSPKHP 112 I ++L+ V P+ + L P H Sbjct: 68 AIIDYLDAVQPEPRLIPLDPLHR 90 >4PXO-A nrPDB Length = 238 Score = 44.0 bits (102), Expect = 5e-05, Method: Composition-based stats. Identities = 33/163 (20%), Positives = 58/163 (35%), Gaps = 17/163 (10%) Query: 40 RLFMILWLKGVVFSVTTVDL----KRKPADLQNLAPGTHPPFITF-NSEVKTDVNKIEEF 94 R+ + L LKG+ + +DL + KP D + P P + + T I ++ Sbjct: 37 RVRIALNLKGIAYEEVFLDLDAGDQHKP-DFLAINPQGAVPALFDGDGPPLTQSLAILDY 95 Query: 95 LEEVLCPPKYLKLSPKHPE-----SNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTLQ 149 LEE L P+ + D + ++ E N L R + Sbjct: 96 LEETRTGVPLLPEEPRARARARSLAQVVACDTHPLYVPRVRTFLME-NYGLPRERMLEFL 154 Query: 150 KLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLL 192 + N+ + + + T RF GD ++ AD L+ Sbjct: 155 R-----NAFITGLKTLETRLSNEAGTGRFCQGDAVSHADLCLI 192 >2GDR-A nrPDB Length = 202 Score = 44.0 bits (102), Expect = 5e-05, Method: Composition-based stats. Identities = 32/166 (19%), Positives = 59/166 (35%), Gaps = 22/166 (13%) Query: 33 GNCPFSQRLFMILWLKGVVFSVTTVDLKRKP----ADLQNLAPGTHPPFI-TFNSEVKTD 87 G C S + L G+ F + VDL K D + P + P + + T+ Sbjct: 8 GACSLSPHI--ALREAGLNFELVQVDLASKKTASGQDYLEVNPAGYVPCLQLDDGRTLTE 65 Query: 88 VNKIEEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKF--SAYIKNSRPEANEALERGLL 145 I +++ + + + L+P + + + F S K+ P N A Sbjct: 66 GPAIVQYVADQVPGKQ---LAPANGSFERYHLQQWLNFISSELHKSFSPLFNPASS---- 118 Query: 146 KTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNL 191 DE+ N+ + +L GD++++AD L Sbjct: 119 ------DEWKNAVRQSLNTRLGQVARQLEHAPYLLGDQLSVADIYL 158 >1AXD-A nrPDB Length = 209 Score = 43.6 bits (101), Expect = 7e-05, Method: Composition-based stats. Identities = 27/201 (13%), Positives = 62/201 (30%), Gaps = 20/201 (9%) Query: 40 RLFMILWLKGVVFSVTTVDL---KRKPADLQNLAPGTHPPFITFNSEVKTDVNKIEEFLE 96 R L G + + ++ + K + P P + + I ++ Sbjct: 16 RCATALEEAGSDYEIVPINFATAEHKSPEHLVRNPFGQVPALQDGDLYLFESRAICKYAA 75 Query: 97 EVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEANEALERGLL---KTLQKLDE 153 P + + + E+ + I + + Y P + L +L + +DE Sbjct: 76 RKNKPELLREGNLE--EAAMVDVWIEVEANQYTAALNPILFQVLISPMLGGTTDQKVVDE 133 Query: 154 YLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHIVKVVAKKYRN--FDIP 211 L + + + + ++L GD ++LAD L+ V V + + Sbjct: 134 NL----EKLKKVLEVYEARLTKCKYLAGDFLSLAD------LNHVSVTLCLFATPYASVL 183 Query: 212 KGMTGIWRYLTNAYSRDEFTN 232 + + + R Sbjct: 184 DAYPHVKAWWSGLMERPSVQK 204 >4PTS-A nrPDB Length = 348 Score = 43.2 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 34/243 (13%), Positives = 78/243 (32%), Gaps = 40/243 (16%) Query: 34 NCPFSQRLFMILWLKGV--VFSVTTVD-LKRKPADLQNLAPGTHPPFITFNSEVKTDVNK 90 CP++ R ++ L G+ V S+ K + +L PG P + + Sbjct: 55 ACPWANRTLIVRRLLGLENVLSLGLCGPTHDKNSWTFDLDPGGVDPVLGI--------PR 106 Query: 91 IEEFLEEVLC--PPKYLKLSPKHPESNTAGMDIFAKFSA-YIKNSRPEANEALERGLLKT 147 +++ E+ P + + + F + + + + + + Sbjct: 107 LKDAYEKRFPGYPKGITVPAVVEIATGEVVTNDFPQITIDFSLEWTAYHRDGAPQLYPEH 166 Query: 148 LQKLDEYLNSPLPDEID------------------------ENSMEDIKFSTRRFLDGDE 183 L+ + ++ + E++ + + + +R+L GD Sbjct: 167 LRAEIDEVSKGIYTEVNNGVYRCGFAGSQDAYDAAYDRLFTKLDELSERLAQQRYLVGDT 226 Query: 184 MTLADCNLLPKLHIVK-VVAKKYR-NFDIPKGMTGIWRYLTNAYSRDEFTNTCPSDKEVE 241 +T AD L L V ++ N M +W Y + + F +T + + Sbjct: 227 ITEADVRLFTTLARFDAVYHGHFKCNRSKLSEMPVLWAYARDLFQTPGFGDTTDFTQIKQ 286 Query: 242 IAY 244 Y Sbjct: 287 HYY 289 >5A5K-A nrPDB Length = 212 Score = 42.9 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 24/166 (14%), Positives = 56/166 (33%), Gaps = 7/166 (4%) Query: 39 QRLFMILWLKGVVFSVTTVDLKR---KPADLQNLAPGTHPPFITFNSEVKTDVNKIEEFL 95 +R+ + L K + F + V+LK K + P P + I +++ Sbjct: 16 RRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYI 75 Query: 96 EEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTLQKLDEYL 155 + L ++ + + P A++ + K++ L Sbjct: 76 AHRY-ENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDE 134 Query: 156 NSPLPDEIDENSMEDIKFSTRR---FLDGDEMTLADCNLLPKLHIV 198 +E + D+ + + +L G+ TL D + +P + + Sbjct: 135 AVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYL 180 >3IR4-A nrPDB Length = 218 Score = 42.9 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 33/183 (18%), Positives = 68/183 (37%), Gaps = 12/183 (6%) Query: 34 NCPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAPGTHPPFITFNSEVKTDVNKIEE 93 +CPF + MI LK + + + + + + P +S + I Sbjct: 11 HCPFCVKARMIFGLKNIPVELNVLQNDDEATPTRMIGQKMVPILQKDDSRYLPESMDIVH 70 Query: 94 FLEEVLCPP-----KYLKLSPKHPESNTAGMDI----FAKFSAYIKNSRPEANEALERGL 144 +++ + P + + + N + FAK SA+ + S P A + R Sbjct: 71 YVDNLDGKPLLTGKRNPAIEEWLRKVNGYVNQLLLPRFAK-SAFDEFSTPAARQYFIRKK 129 Query: 145 LKTLQKLDEYL--NSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHIVKVVA 202 + D +L ++ L +I ++ K + E++ D +L P L + +VA Sbjct: 130 EASSGSFDNHLAHSAGLIKKIGDDLRLLDKLIVQPNAVNGELSEDDIHLFPLLRNLTLVA 189 Query: 203 KKY 205 + Sbjct: 190 GIH 192 >1U3I-A nrPDB Length = 211 Score = 42.5 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 31/206 (15%), Positives = 71/206 (34%), Gaps = 23/206 (11%) Query: 39 QRLFMILWLKGVVFSVTTVDLKRKPADLQNLAPGTHPPFITFNS-----EVKTDVNKIEE 93 + + M L GV + + + P ++ PG P + + + I Sbjct: 18 ESIRMTLVAAGVDYEDERISFQDWPK-IKPTIPGGRLPAVKVTDDHGHVKWMLESLAIAR 76 Query: 94 FLEEVLCPPKYLKLSPKHPESNTAG---MDIFAKFSAYIKNSRPEANEALERGLLKTLQK 150 ++ + + ++ D+ ++ + + E + + Sbjct: 77 YMAKK--HHMMGETDEEYYSVEKLIGQAEDVEHEYHKTLMKPQEEKEKITK--------- 125 Query: 151 LDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHIVKVVAKKYRNFDI 210 E LN +P + E +K ST + GD++TLAD L+ + V + K + Sbjct: 126 --EILNGKVP-VLFNMICESLKGSTGKLAVGDKVTLADLVLIAVIDHVTDLDKGFLTGKY 182 Query: 211 PKGMTGIWRYLTNAYSRDEFTNTCPS 236 P+ L ++ ++ + P+ Sbjct: 183 PEIHKHRENLLASSPRLAKYLSNRPA 208 >6N0I-A nrPDB Length = 706 Score = 42.5 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 29/175 (16%), Positives = 63/175 (36%), Gaps = 13/175 (7%) Query: 74 HPPFITFNSEVK---TDVNKIEEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIK 130 H P + + +++ D ++ + +++ L E N G K A Sbjct: 138 HVPRLAYINKMDRQGADFLRVVKQIDQRLGHHPVPIQLAIGSEENFMGQIDLVKMKAIYW 197 Query: 131 NSRPEANEALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCN 190 N + E + L+ L + + + E + E T +FLDG+E+++ + Sbjct: 198 NDADQGTSYREEEIPAELKALADEWRAH----MIEAAAEANDELTMKFLDGEELSIEEIK 253 Query: 191 LLPKLHIV------KVVAKKYRNFDIPKGMTGIWRYLTNAYSRDEFTNTCPSDKE 239 + + ++ ++N +P + + YL T P D+E Sbjct: 254 AGLRQRTIANEIVPTILGSSFKNKGVPLMLDAVIDYLPAPSEIPAIRGTDPDDEE 308 >2GLR-A nrPDB Length = 209 Score = 42.5 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 34/205 (16%), Positives = 63/205 (30%), Gaps = 21/205 (10%) Query: 38 SQRLFMILWLKGVVFSVTTVDLKRKPADLQN-LAPGTHPPFITFNSEVKTDVNKIEEFLE 96 + + M+L +G + V + L P N I L Sbjct: 14 CEAMRMLLADQGQSWKEEVVTIDTWMQGLLKPTCLYGQLPKFEDGDLTLYQSNAILRHLG 73 Query: 97 EVLC-PPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTLQKLDEYL 155 L K + + + N D+ K+ I + + L L+ + L Sbjct: 74 RSLGLYGKNQREAAQMDMVNDGVEDLRGKYVTLIYTNYENGKNDYVKALPGHLKPFETLL 133 Query: 156 NSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHIVKVVAKKYRNFDIPKGMT 215 + + F+ GD+++ AD NLL L I +V+A + Sbjct: 134 SQ--------------NQGGKAFIVGDQISFADYNLLDLLLIHQVLAPGCLD-----NFP 174 Query: 216 GIWRYLTNAYSRDEFTNTCPSDKEV 240 + Y+ +R + S + V Sbjct: 175 LLSAYVARLSARPKIKAFLSSPEHV 199 >2CA8-A nrPDB Length = 211 Score = 42.1 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 32/196 (16%), Positives = 68/196 (34%), Gaps = 27/196 (13%) Query: 39 QRLFMILWLKGVVFSVTTVDLKRKPADLQNLAPGTHPPFITFNS-----EVKTDVNKIEE 93 + + M L GV + + + P ++ PG P + + + I Sbjct: 18 ESIRMTLVAAGVNYEDERISFQDWPK-IKPTIPGGRLPAVKITDNHGHVKWMVESLAIAR 76 Query: 94 FLEEVLCPPKYLKLSPKHPESNTAG---MDIFAKFSAYIKNSRPEANEALERGLLKTLQK 150 ++ + ++ D+ ++ + E + Sbjct: 77 YMAKK--HHMMGGTEEEYYNVEKLIGQAEDLEHEYYKTLMKPEEEKQ-----------KI 123 Query: 151 LDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHIVKVVAKKYRNFDI 210 + E LN +P +D E +K ST + GD++TLAD L+ + V + K++ Sbjct: 124 IKEILNGKVPVLLD-IICESLKASTGKLAVGDKVTLADLVLIAVIDHVTDLDKEFLTGKY 182 Query: 211 PKGMTGIWRYLTNAYS 226 P+ I ++ N + Sbjct: 183 PE----IHKHRENLLA 194 >1V2A-A nrPDB Length = 210 Score = 42.1 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 38/220 (17%), Positives = 69/220 (31%), Gaps = 44/220 (20%) Query: 35 CPFSQRLFMILWLKGVVFSVTTVDLKRKPAD--LQNLAPGTHPPFITFNSEVKTDVNKIE 92 P Q ++ G+ ++ ++ L L P P + N V + I Sbjct: 9 SPPCQSAILLAKKLGITLNLKKTNVHDPVERDALTKLNPQHTIPTLVDNGHVVWESYAIV 68 Query: 93 EFLEEVLCPPKYLKLSPKHPESNTAGMD-IFAKFSAYIK----------NSRPEANEALE 141 +L E L PK P+ + +F K ++E +E Sbjct: 69 LYLVETYAKDD--TLYPKDPKVRSVVNQRLFFDIGTLYKRIIDVIHLVMKKEQPSDEQME 126 Query: 142 RGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHIVKVV 201 + L L L++++ R + D +T+AD LL V Sbjct: 127 K-LKGALDLLEQFVT------------------ERAYAAADHLTVADICLLG-----TVT 162 Query: 202 AKKYRNFDIPKGMTGIWRYLTNAYSR----DEFTNTCPSD 237 A + D+ + I +L + +EF+ D Sbjct: 163 ALNWLKHDL-EPFPHIRAWLERVRAEMPDYEEFSKQVADD 201 >3VWX-A nrPDB Length = 222 Score = 42.1 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 29/206 (14%), Positives = 57/206 (27%), Gaps = 17/206 (8%) Query: 32 IGNCPFSQRLFMILWLKGVVFSVTTVDLKRK---PADLQNLAPGTHPPFITFNSEVKTDV 88 I P + + L + F V+L K + P P + + + D Sbjct: 9 IDPSPPVRACLLTLKALNLPFEYKVVNLFAKEHLSEEYLKKNPQHTVPTLEEDGHLIWDS 68 Query: 89 NKIEEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTL 148 + I +L L + F + R R Sbjct: 69 HAIMAYLVSKYGKDDSLYPKDLLKRAVVDQRMYFEAGVLFQGGLRNITAPLFFRN----- 123 Query: 149 QKLDEYLNSPLPDEIDENSMEDIKF-STRRFLDGDEMTLADCNLLPKLHIVKVVAKKYRN 207 + D I E+ F +++ GD +T+AD +++ + + Sbjct: 124 ---QTQIPQHQIDSIVESYGFLESFLKNNKYMAGDHLTIADFSIVTSV----TSLVAFAE 176 Query: 208 FDIPKGMTGIWRYLTNAYSRDEFTNT 233 D K + +L + S + Sbjct: 177 IDQSK-FPKLSAWLKSLQSLPFYEEA 201 >3PR8-A nrPDB Length = 229 Score = 40.9 bits (94), Expect = 5e-04, Method: Composition-based stats. Identities = 29/173 (16%), Positives = 58/173 (33%), Gaps = 8/173 (4%) Query: 43 MILWLKGVVFSVTTVDLKRKPADLQNLAPGTHPPFITFNSEVKTDVNKIEEFLEEVLCPP 102 + L KG+ F T + P L ++P P + ++ + I +++E+ Sbjct: 19 LALLEKGLTFEEVTFYGGQAPQAL-EVSPRGKVPVLETEHGFLSETSVILDYIEQT---Q 74 Query: 103 KYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTLQKLDEYLNSPLPDE 162 L P P ++ + YI+ G+ + E + D Sbjct: 75 GGKALLPADPFGQAKVRELLKEIELYIELPARTCYAESFFGMSVEPL-IKEKARA---DL 130 Query: 163 IDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHIVKVVAKKYRNFDIPKGMT 215 + + ++ G+++TLAD + + V KK N D Sbjct: 131 LAGFATLKRNGRFAPYVAGEQLTLADLMFCFSVDLANAVGKKVLNIDFLADFP 183 >6GZF-A nrPDB Length = 341 Score = 39.8 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 19/77 (24%), Positives = 28/77 (36%), Gaps = 2/77 (2%) Query: 170 DIKFSTRRFLDGDEMTLADCNLLPKLHIVK-VVAKKY-RNFDIPKGMTGIWRYLTNAYSR 227 D + +R+L GD +T AD + L V + N + +W YL + Y Sbjct: 222 DDVLADQRYLAGDRLTEADIAMFTTLVRFDNVYHTHFMCNVQYIREFDNLWPYLRDLYQT 281 Query: 228 DEFTNTCPSDKEVEIAY 244 T D E Y Sbjct: 282 HGIAETVEMDHITEHYY 298 >18GS-A nrPDB Length = 210 Score = 38.2 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 34/208 (16%), Positives = 63/208 (30%), Gaps = 27/208 (12%) Query: 38 SQRLFMILWLKGVVFSVTTVDLKRKPA-DLQNLAPGTHPPFITFNSEVKTDVNKIEEFLE 96 L M+L +G + V ++ L+ P N I L Sbjct: 15 CAALRMLLADQGQSWKEEVVTVETWQEGSLKASCLYGQLPKFQDGDLTLYQSNTILRHLG 74 Query: 97 EVLCPPKYLKLSPKHPE----SNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTLQKLD 152 L + N D+ K+ + I + + + L L+ + Sbjct: 75 RTL---GLYGKDQQEAALVDMVNDGVEDLRCKYISLIYTNYEAGKDDYVKALPGQLKPFE 131 Query: 153 EYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHIVKVVAKKYRNFDIPK 212 L+ + F+ GD+++ AD NLL L I +V+A + Sbjct: 132 TLLSQ--------------NQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLD----- 172 Query: 213 GMTGIWRYLTNAYSRDEFTNTCPSDKEV 240 + Y+ +R + S + V Sbjct: 173 AFPLLSAYVGRLSARPKLKAFLASPEYV 200 >2C3Q-A nrPDB Length = 247 Score = 38.2 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 29/175 (16%), Positives = 55/175 (31%), Gaps = 27/175 (15%) Query: 38 SQRLFMILWLKGVVFSVTTVDL---KRKPADLQNLAPGTHPPFITFNSEVKTDVNKIEEF 94 + +++ + F + VDL + + P P + T+ I + Sbjct: 21 CRAVYIFAKKNDIPFELRIVDLIKGQHLSDAFAQVNPLKKVPALKDGDFTLTESVAILLY 80 Query: 95 LEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEA------------NEALER 142 L P Y P+ ++ + A ++ S A + Sbjct: 81 LTRKYKVPDYW--YPQDLQARARVDEYLAWQHTTLRRSCLRALWHKVMFPVFLGEPVSPQ 138 Query: 143 GLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLHI 197 L TL +LD + +ED + FL G ++LAD + +L Sbjct: 139 TLAATLAELD----------VTLQLLEDKFLQNKAFLTGPHISLADLVAITELMH 183 >1G6W-A nrPDB Length = 261 Score = 37.5 bits (85), Expect = 0.006, Method: Composition-based stats. Identities = 32/243 (13%), Positives = 71/243 (29%), Gaps = 47/243 (19%) Query: 33 GNCPFSQR-------LFMILWLKGVVFSVTTVDL---KRKPADLQNLAPGTHPPFITF-- 80 G FS R + ++L G ++ +D + + + ++ P P + Sbjct: 20 GYTLFSHRSAPNGFKVAIVLSELGFHYNTIFLDFNLGEHRAPEFVSVNPNARVPALIDHG 79 Query: 81 -NSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHPESNTAGMD---IFAK------------ 124 ++ + I L L ++ + ++ F Sbjct: 80 MDNLSIWESGAILLHLVNKYYKETGNPLLWSDDLADQSQINAWLFFQTSGHAPMIGQALH 139 Query: 125 FSAYIKNSRPEANEALERGLLKTLQKLDEYLNSPLPDEIDENSME--------DIKFSTR 176 F + A E + + ++ L + E E S Sbjct: 140 FRYFHSQKIASAVERYTDEVRRVYGVVEMALAERREALVMELDTENAAAYSAGTTPMSQS 199 Query: 177 RFLD------GDEMTLADCNLLPKLHIVKVVAKKYRNFDIPKGMTGIWRYLTNAYSRDEF 230 RF D GD++T+AD +P ++V + +I ++++ + R Sbjct: 200 RFFDYPVWLVGDKLTIADLAFVPWNNVVDRI-----GINIKIEFPEVYKWTKHMMRRPAV 254 Query: 231 TNT 233 Sbjct: 255 IKA 257 >4MDC-A nrPDB Length = 252 Score = 35.5 bits (80), Expect = 0.019, Method: Composition-based stats. Identities = 29/215 (13%), Positives = 59/215 (27%), Gaps = 35/215 (16%) Query: 35 CPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAPGTHPPFITFNS-EVKTDVNKIEE 93 P S+ + +IL G ++ D L P P +S I E Sbjct: 32 SPASRFVRLILSEYGYQTELSEEQPWENRRDFLTLNPAGTLPVYVDDSMRALCGATIISE 91 Query: 94 FLEEVLC----PPKYLKLSP-KHPESNTAGMDIFAKFSAYIKNS-----------RPEAN 137 +L+E + L P + E K A + P+ Sbjct: 92 YLDETSGIMKRDRRLLAEDPFQRAEIRRLTEWFLQKMEADVTRPLVRERIFKLQMTPDQG 151 Query: 138 EALE--RGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKL 195 + L + + +++ +R +L GD ++ D + Sbjct: 152 GGAPDSKILRTSRSNIRQHMKYL-----------SWLAGSRPWLAGDRISYGDLAAAAAI 200 Query: 196 HIVKVVAKKYRNFDIPKGMTGIWRYLTNAYSRDEF 230 ++ + + ++ + SR F Sbjct: 201 SVLDYLGE--IDWS---DAPTAKEWYQRLKSRPSF 230 >4FN5-A nrPDB Length = 709 Score = 35.5 bits (80), Expect = 0.021, Method: Composition-based stats. Identities = 31/194 (15%), Positives = 60/194 (30%), Gaps = 15/194 (7%) Query: 57 VDLKRKPADLQNLAPGTHPPFITFN--SEVKTDVNKIEEFLEEVLCPPKYLKLSPKHPES 114 V+ + + + P + N + ++ E +++ L E Sbjct: 122 VEPQSETVW-RQANKYGVPRIVYVNKMDRQGANFLRVVEQIKKRLGHTPVPVQLAIGAEE 180 Query: 115 NTAGMDIFAKFSAYIKNSRPEANEALERGLLKTLQKLDEYLNSPLPDEIDENSM------ 168 N G K A N + E + L+ L E S + + E + Sbjct: 181 NFVGQVDLIKMKAIYWNDDDKGMTYREEEIPAELKDLAEEWRSSMVEAAAEANEELMNKY 240 Query: 169 -EDIKFSTRRFLDGDEMTLADCNLLPKLHIVKVVAKKYRNFDIPKGMTGIWRYLTNAYSR 227 E+ + S +G + C ++P V ++N +P + + YL Sbjct: 241 LEEGELSEAEIKEGLRLRTLACEIVP-----AVCGSSFKNKGVPLVLDAVIDYLPAPTEI 295 Query: 228 DEFTNTCPSDKEVE 241 P D+ VE Sbjct: 296 PAIKGVSPDDETVE 309 >4USS-A nrPDB Length = 325 Score = 35.2 bits (79), Expect = 0.030, Method: Composition-based stats. Identities = 40/252 (15%), Positives = 76/252 (30%), Gaps = 47/252 (18%) Query: 34 NCPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAPGTH-----PPFITFNSEVKTDV 88 CP++ R L +KG+ KP + H P T + + D Sbjct: 48 ACPWASRCLAYLKIKGL--EKAIAFTSVKPIWERTKESDEHMGWVFPASETEEAGAEPDT 105 Query: 89 N----KIEEFLE--EVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEANEALER 142 I E E KY + T + + S I+ E N+ E Sbjct: 106 LNGARSIRELYELASTNYAGKYTVPVLWDKKLKTIVNN---ESSEIIRMFNTEFNDIAEN 162 Query: 143 GLLK----TLQKL------------------DEYLNSPLPDE------IDENSMEDIKFS 174 L LQ + P E + + Sbjct: 163 AALDLYPSHLQAQIDETNGWVYDGINNGVYKCGFARKQGPYEEAAIQLYEALDKCEEILG 222 Query: 175 TRRFLDGDEMTLADCNLLPKLHIV-KVVAKKYR-NFDIPKGMTGIWRYLTNAYSRDEFTN 232 +R++ G+ ++ AD L L +V A ++ N + + ++ Y + + ++ Sbjct: 223 RQRYICGNTLSEADIKLFVTLIRFDEVYAVHFKCNKKLLRDYPNMFNYTKDIFQIPGMSS 282 Query: 233 TCPSDKEVEIAY 244 T + + ++ Y Sbjct: 283 TV-NMQHIKRHY 293 >2IL3-A nrPDB Length = 221 Score = 34.8 bits (78), Expect = 0.037, Method: Composition-based stats. Identities = 18/90 (20%), Positives = 30/90 (33%), Gaps = 7/90 (7%) Query: 35 CPFSQRLFMILWLKGVVFSVTTVDLKR----KPADLQNLAPGTHPPFITFNSEVKTDVNK 90 P + + + G+ T++L KP L P P + N + T+ + Sbjct: 12 SPPCRAVELTAKALGLELEQKTINLLTGDHLKPE-FVKLNPQHTIPVLDDNGTIITESHA 70 Query: 91 IEEFLEEVLCPPK--YLKLSPKHPESNTAG 118 I +L Y K K N+A Sbjct: 71 IMIYLVTKYGKDDSLYPKDPVKQARVNSAL 100 >4LMW-A nrPDB Length = 251 Score = 34.4 bits (77), Expect = 0.048, Method: Composition-based stats. Identities = 43/209 (20%), Positives = 75/209 (35%), Gaps = 33/209 (15%) Query: 26 GSDGESIGNCPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNL-APGTH---------- 74 ++ + P + + +L KG+ + V+ A + + AP T Sbjct: 13 ANEPRQMAWGPNTWKTRYVLNFKGLKYRTEWVEYPDIEAVCKQIGAPATEKKPDGRDHYT 72 Query: 75 PPFITF--NSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHPESN----------TAGMDIF 122 P I V D + I ++LE P +L P+ + + M IF Sbjct: 73 LPVIQDPNTKAVVADSDAIAKYLESTY--PDTPRLFPEGTRAFQHAFYQLARPSVLMPIF 130 Query: 123 AKFSAYI-KNSRPEANE----ALERGLLKTLQKL---DEYLNSPLPDEIDENSMEDIKFS 174 A + K RP + E E+ L K L+++ D++ ++S+E Sbjct: 131 NIVVARVWKLLRPRSQEYFRATREQMLGKKLEEIGSEDDWNALESGLARIKSSLEANGAG 190 Query: 175 TRRFLDGDEMTLADCNLLPKLHIVKVVAK 203 L GD +T AD L ++V A Sbjct: 191 KDLLLMGDRVTFADLQLASLFIWLRVSAG 219 >2PVQ-A nrPDB Length = 201 Score = 34.0 bits (76), Expect = 0.057, Method: Composition-based stats. Identities = 30/157 (19%), Positives = 52/157 (33%), Gaps = 28/157 (17%) Query: 43 MILWLKGVVFSVTTVDLKRKPA----DLQNLAPGTHPPFI-TFNSEVKTDVNKIEEFLEE 97 +IL G+ + + VDLK K D + P P + V T I +++ + Sbjct: 16 IILSEAGLPYELEAVDLKAKKTADGGDYFAVNPRGAVPALEVKPGTVITQNAAILQYIGD 75 Query: 98 -----VLCPPKYLKLSPKHPESNTAGMDIFAKFS-AYIKNSRPEANEALERGLLKTLQKL 151 P + E+ D+ A FS + N EA + + + L +L Sbjct: 76 HSDVAAFKPAYGSIERARLQEALGFCSDLHAAFSGLFAPNLSEEARAGVIANINRRLGQL 135 Query: 152 DEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLAD 188 + L+ + GD+ T D Sbjct: 136 EAMLSD-----------------KNAYWLGDDFTQPD 155 >2PPQ-A nrPDB Length = 322 Score = 33.6 bits (75), Expect = 0.077, Method: Composition-based stats. Identities = 12/57 (21%), Positives = 27/57 (47%) Query: 129 IKNSRPEANEALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMT 185 + + E + +E+GL + ++ +YL + P ++ + F F GDE++ Sbjct: 151 LWDKSEERADEVEKGLREEIRPEIDYLAAHWPKDLPAGVIHADLFQDNVFFLGDELS 207 >4FQU-A nrPDB Length = 313 Score = 32.1 bits (71), Expect = 0.23, Method: Composition-based stats. Identities = 26/144 (18%), Positives = 48/144 (33%), Gaps = 30/144 (20%) Query: 75 PPFI---TFNSEVKTDVNKIEEFL----EEVLCPPKYLKLSPKHPESNTAGMDIFAKFSA 127 P + + + ++I L ++V P + PE + ++ + Sbjct: 122 IPILWDKVEKRILNNESSEIIRILNSAFDDVGALPGDYYPAEFRPEIDRINARVYETLNN 181 Query: 128 YI-KNSRPEANEALERG---LLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDE 183 + ++ EA E L TL L+E+L R +L GD Sbjct: 182 GVYRSGFATTQEAYEEAFYPLFDTLDWLEEHLTG------------------REWLVGDR 223 Query: 184 MTLADCNLLPKLHIVKVVA-KKYR 206 +T AD L P L + ++ Sbjct: 224 LTEADIRLFPTLVRFDAIYHGHFK 247 >3PL2-A nrPDB Length = 319 Score = 30.9 bits (68), Expect = 0.48, Method: Composition-based stats. Identities = 15/61 (24%), Positives = 21/61 (34%), Gaps = 1/61 (1%) Query: 31 SIGNCPFSQRLFMILWLKGVVFS-VTTVDLKRKPADLQNLAPGTHPPFITFNSEVKTDVN 89 +GN PF + L L GV V T + P + P P + D+N Sbjct: 63 RVGNDPFGEYLLAELERLGVDNQYVATDQTFKTPVTFCEIFPPDDFPLYFYREPKAPDLN 122 Query: 90 K 90 Sbjct: 123 I 123 >2PBJ-A nrPDB Length = 290 Score = 30.9 bits (68), Expect = 0.50, Method: Composition-based stats. Identities = 16/131 (12%), Positives = 39/131 (29%), Gaps = 21/131 (16%) Query: 34 NCPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAPGTHPPFIT----FNSEVKTDVN 89 CPF ++ L + + V V+ + + P + +S+ D + Sbjct: 22 TCPFCSKVRAFLDFHALPYQVVEVNPVLRAE--IKFSSYRKVPILVAQEGESSQQLNDSS 79 Query: 90 KIEEFLEEVLCP-----------PKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEANE 138 I L+ L P ++ + E G K+ + + Sbjct: 80 VIISALKTYLVSGQPLEEIITYYPAMKAVNDQGKEVTEFGN----KYWLMLNEKEAQQVY 135 Query: 139 ALERGLLKTLQ 149 + + + ++ Sbjct: 136 SGKEARTEEMK 146 >6GCB-A nrPDB Length = 325 Score = 30.5 bits (67), Expect = 0.64, Method: Composition-based stats. Identities = 24/112 (21%), Positives = 44/112 (39%), Gaps = 8/112 (7%) Query: 137 NEALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRRFLDGDEMTLADCNLLPKLH 196 N + + T Q+ E PL + +D + + + +L GD++T AD L + Sbjct: 189 NNGVYKAGFATTQQAYEAAVIPLFESLDRL---EKILTGKDYLVGDQLTEADVRLFVTII 245 Query: 197 IVKVV-AKKYRN--FDIPKGMTGIWRYLTNAY-SRDEFTNTCPSDKEVEIAY 244 ++ I G I +L Y + F+ TC D ++ +Y Sbjct: 246 RFDPAYVGHFKCNLRTIRDGYPAIHLWLRKLYWNNSAFSETCKFD-HIKASY 296 >3QMX-A nrPDB Length = 99 Score = 30.1 bits (66), Expect = 0.95, Method: Composition-based stats. Identities = 12/36 (33%), Positives = 16/36 (44%) Query: 23 VKAGSDGESIGNCPFSQRLFMILWLKGVVFSVTTVD 58 V A + + CPF R +L KGV F +D Sbjct: 14 VSAKIEIYTWSTCPFCMRALALLKRKGVEFQEYCID 49 >4G0L-A nrPDB Length = 328 Score = 29.4 bits (64), Expect = 1.6, Method: Composition-based stats. Identities = 37/244 (15%), Positives = 75/244 (30%), Gaps = 42/244 (17%) Query: 34 NCPFSQRLFMILWLKGV-VF-SVTTVD--LKRKPADLQNLAPGTHPPFITFNSEVKTDVN 89 CP++ R ++ LKG+ F SV+ V+ + + PG + Sbjct: 62 ACPWAHRTLIMRKLKGLEPFISVSVVNPLMLENGWTFDDSFPGA-------TGDTLYQNE 114 Query: 90 KIEEFLEEVLCPPKYLKLSPK--HPESNTAGMD----IFAKFSAYIKNSRPEANEALERG 143 + + P +++T + I F+ +A + Sbjct: 115 FLYQLYLHADPHYSGRVTVPVLWDKKNHTIVSNESAEIIRMFNTAFDALGAKAGDYYPPA 174 Query: 144 LLKTLQKLDEYL---------------NSPLPDEIDENSME-----DIKFSTRRFLDGDE 183 L + +L+ ++ + DE E + R+L G++ Sbjct: 175 LQTKIDELNGWIYDTVNNGVYKAGFATSQEAYDEAVAKVFESLARLEQILGQHRYLTGNQ 234 Query: 184 MTLADCNLLPKLHIVK-VVAKKYR--NFDIPKGMTGIWRYLTNAYSRDEFTNTCPSDKEV 240 +T AD L L V ++ I + ++ +L + Y T D + Sbjct: 235 LTEADIRLWTTLVRFDPVYVTHFKCDKHRISDYL-NLYGFLRDIYQMPGIAETVNFD-HI 292 Query: 241 EIAY 244 Y Sbjct: 293 RNHY 296 >6A94-A nrPDB Length = 376 Score = 28.6 bits (62), Expect = 2.8, Method: Composition-based stats. Identities = 7/41 (17%), Positives = 17/41 (41%) Query: 206 RNFDIPKGMTGIWRYLTNAYSRDEFTNTCPSDKEVEIAYSD 246 + +P + +W YL +S + + C + +A + Sbjct: 73 YRWPLPSKLCAVWIYLDVLFSTAKIWHLCAISLDRYVAIQN 113 >4IP6-A nrPDB Length = 132 Score = 27.4 bits (59), Expect = 6.0, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 25/76 (32%), Gaps = 10/76 (13%) Query: 111 HPESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTLQKLDEYLNSPLPDEIDENSMED 170 P+ A D + + AN+A + LLK L L P D E Sbjct: 52 DPQVQKALAD------TVLLAANVTANDAQDVALLKHLNV----LGLPTILFFDGQGQEH 101 Query: 171 IKFSTRRFLDGDEMTL 186 + F+D + + Sbjct: 102 PQARVTGFMDAETFSA 117 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.306 0.124 0.309 Lambda K H 0.267 0.0381 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 8,591,219 Number of Sequences: 36641 Number of extensions: 317642 Number of successful extensions: 1031 Number of sequences better than 10.0: 87 Number of HSP's better than 10.0 without gapping: 71 Number of HSP's successfully gapped in prelim test: 53 Number of HSP's that attempted gapping in prelim test: 881 Number of HSP's gapped (non-prelim): 130 length of query: 253 length of database: 10,336,785 effective HSP length: 95 effective length of query: 158 effective length of database: 6,855,890 effective search space: 1083230620 effective search space used: 1083230620 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 58 (27.1 bits)