BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9QXT8 (256 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2JUL-A nrPDB 538 e-154 3DD4-A nrPDB 336 6e-93 1S1E-A nrPDB 309 6e-85 1S6C-A nrPDB 300 4e-82 2E6W-A nrPDB 192 1e-49 2LCP-A nrPDB 173 6e-44 2L2E-A nrPDB 166 9e-42 2JU0-A nrPDB 161 3e-40 5T7C-A nrPDB 157 3e-39 5M6C-E nrPDB 157 4e-39 1BJF-A nrPDB 155 1e-38 6EPA-A nrPDB 155 2e-38 2I94-A nrPDB 132 2e-31 2D8N-A nrPDB 128 2e-30 1JBA-A nrPDB 116 9e-27 2R2I-A nrPDB 99 3e-21 2NA0-A nrPDB 97 5e-21 2GGZ-A nrPDB 84 4e-17 1V1G-A nrPDB 79 2e-15 5YPX-A nrPDB 79 2e-15 5B8I-B nrPDB 65 4e-11 4IL1-A nrPDB 60 8e-10 4ORC-B nrPDB 60 1e-09 1UHN-A nrPDB 59 3e-09 2ZFD-A nrPDB 59 3e-09 2TN4-A nrPDB 52 4e-07 2L1W-A nrPDB 51 6e-07 1TOP-A nrPDB 51 6e-07 2N6A-A nrPDB 48 3e-06 5A2H-A nrPDB 48 4e-06 5I0I-E nrPDB 48 5e-06 4E53-A nrPDB 48 5e-06 2F2P-A nrPDB 48 5e-06 6O20-F nrPDB 48 5e-06 1DTL-A nrPDB 47 6e-06 3WFN-B nrPDB 47 6e-06 3EK4-A nrPDB 47 6e-06 4JWQ-A nrPDB 47 7e-06 3K21-A nrPDB 47 8e-06 3U0K-A nrPDB 47 1e-05 6HCS-A nrPDB 46 1e-05 3NCG-A nrPDB 46 1e-05 2E30-A nrPDB 46 2e-05 2BEC-A nrPDB 45 2e-05 1JFJ-A nrPDB 45 3e-05 3QRX-A nrPDB 45 3e-05 4OY4-A nrPDB 45 4e-05 5ZOR-A nrPDB 44 8e-05 2JNF-A nrPDB 42 2e-04 1SNL-A nrPDB 42 2e-04 1CLM-A nrPDB 42 3e-04 1GGZ-A nrPDB 41 6e-04 3O4Y-A nrPDB 41 6e-04 2JNX-A nrPDB 41 6e-04 4I2Y-A nrPDB 40 7e-04 3Q5I-A nrPDB 40 9e-04 2HF5-A nrPDB 40 0.001 2LM5-A nrPDB 40 0.001 5E37-A nrPDB 40 0.001 5UKG-A nrPDB 40 0.001 2BL0-C nrPDB 39 0.002 2M29-A nrPDB 39 0.002 1JC2-A nrPDB 39 0.002 2KSZ-A nrPDB 39 0.002 4WPX-A nrPDB 39 0.003 3KHE-A nrPDB 39 0.003 1DGU-A nrPDB 38 0.003 3HZT-A nrPDB 38 0.004 5JN2-A nrPDB 38 0.004 3AAJ-A nrPDB 38 0.005 1OZS-A nrPDB 37 0.006 2MA2-A nrPDB 37 0.006 4YZB-A nrPDB 37 0.008 1S6I-A nrPDB 37 0.009 3FWC-A nrPDB 36 0.014 2NCO-A nrPDB 36 0.015 2I18-A nrPDB 36 0.020 3UL4-B nrPDB 35 0.024 1YX7-A nrPDB 35 0.027 4N5X-A nrPDB 35 0.028 5D43-A nrPDB 35 0.036 2KGR-A nrPDB 35 0.039 2RO8-A nrPDB 35 0.040 4ZCV-A nrPDB 35 0.044 2LMV-A nrPDB 35 0.046 4RGJ-A nrPDB 34 0.065 2AAO-A nrPDB 34 0.078 2GGM-A nrPDB 33 0.082 1C7W-A nrPDB 33 0.082 2ROB-A nrPDB 33 0.091 2KN2-A nrPDB 33 0.11 4MVF-A nrPDB 33 0.15 3E3R-A nrPDB 33 0.15 2OBH-A nrPDB 33 0.16 3L19-A nrPDB 32 0.23 2SAS-A nrPDB 32 0.23 3KF9-A nrPDB 32 0.24 3PM8-A nrPDB 32 0.25 2LV7-A nrPDB 32 0.29 2M97-A nrPDB 32 0.31 3LIJ-A nrPDB 32 0.32 2I08-A nrPDB 32 0.33 2PMY-A nrPDB 32 0.38 4MSP-A nrPDB 31 0.41 4Q57-A nrPDB 31 0.48 5H7D-E nrPDB 31 0.49 2RO9-A nrPDB 31 0.50 5OTJ-D nrPDB 31 0.51 3I5H-B nrPDB 31 0.52 3IFK-A nrPDB 31 0.55 2AMI-A nrPDB 31 0.65 2HPS-A nrPDB 30 0.70 3LCP-C nrPDB 30 0.71 2VRG-A nrPDB 30 0.71 5COC-A nrPDB 30 0.73 5AQM-B nrPDB 30 0.73 1NYA-A nrPDB 30 0.84 2B1U-A nrPDB 30 0.86 1TNP-A nrPDB 30 0.87 5LS0-A nrPDB 30 0.88 3A4U-B nrPDB 30 0.90 1B7T-Y nrPDB 30 1.1 2LVK-A nrPDB 30 1.1 4YGB-B nrPDB 30 1.1 5Z1Q-A nrPDB 30 1.2 1DFK-Y nrPDB 30 1.2 2JOJ-A nrPDB 30 1.4 4BTS-A7 nrPDB 30 1.4 1TRF-A nrPDB 30 1.4 1OQP-A nrPDB 30 1.4 1TIZ-A nrPDB 29 1.6 1CB1-A nrPDB 29 1.7 1A75-A nrPDB 29 1.7 5MWC-D nrPDB 29 1.8 3MSE-B nrPDB 29 1.8 4PAL-A nrPDB 29 1.8 3PAT-A nrPDB 29 1.9 1FW4-A nrPDB 29 2.0 3J04-B nrPDB 29 2.0 5ZGM-A nrPDB 29 2.5 2OPO-A nrPDB 29 2.6 5XND-A nrPDB 28 2.8 2GS3-A nrPDB 28 2.8 5LWF-A nrPDB 28 3.1 1S6J-A nrPDB 28 3.4 5L71-A nrPDB 28 3.5 5PAL-A nrPDB 28 3.7 4LRY-C nrPDB 28 3.9 2LC5-A nrPDB 28 4.0 3JPZ-A nrPDB 28 4.2 2M5E-A nrPDB 28 4.9 1Y1X-A nrPDB 28 5.0 6AGH-A nrPDB 28 5.6 1QX2-A nrPDB 27 5.8 1T70-A nrPDB 27 5.9 3DTP-E nrPDB 27 7.0 3KPX-A nrPDB 27 7.1 2KZ2-A nrPDB 27 8.0 >2JUL-A nrPDB Length = 256 Score = 538 bits (1386), Expect = e-154, Method: Compositional matrix adjust. Identities = 256/256 (100%), Positives = 256/256 (100%) Query: 1 MQRTKEAVKASDGNLLGDPGRIPLSKRESIKWQRPRFTRQALMRCCLIKWILSSAAPQGS 60 MQRTKEAVKASDGNLLGDPGRIPLSKRESIKWQRPRFTRQALMRCCLIKWILSSAAPQGS Sbjct: 1 MQRTKEAVKASDGNLLGDPGRIPLSKRESIKWQRPRFTRQALMRCCLIKWILSSAAPQGS 60 Query: 61 DSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQ 120 DSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQ Sbjct: 61 DSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQ 120 Query: 121 FFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDG 180 FFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDG Sbjct: 121 FFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDG 180 Query: 181 CITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQ 240 CITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQ Sbjct: 181 CITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQ 240 Query: 241 KDENIMNSMQLFENVI 256 KDENIMNSMQLFENVI Sbjct: 241 KDENIMNSMQLFENVI 256 >3DD4-A nrPDB Length = 229 Score = 336 bits (862), Expect = 6e-93, Method: Compositional matrix adjust. Identities = 155/196 (79%), Positives = 178/196 (90%) Query: 61 DSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQ 120 DS + ELE++TVRH+PE L+ L+AQ+KFTKKELQ LYRGFKNECP+G+V+E+TFK IYSQ Sbjct: 34 DSVEDELEMATVRHRPEALELLEAQSKFTKKELQILYRGFKNECPSGVVNEETFKEIYSQ 93 Query: 121 FFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDG 180 FFPQGD+TTYAHFLFNAFD D NGA+ FEDF+ GLSILLRGTV EKL WAFNLYDINKDG Sbjct: 94 FFPQGDSTTYAHFLFNAFDTDHNGAVSFEDFIKGLSILLRGTVQEKLNWAFNLYDINKDG 153 Query: 181 CITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQ 240 ITKEEML IMK+IYDMMG+ TYP+L+EDAP +HVE FFQKMD+N+DGVVTIDEF+E+CQ Sbjct: 154 YITKEEMLDIMKAIYDMMGKCTYPVLKEDAPRQHVETFFQKMDKNKDGVVTIDEFIESCQ 213 Query: 241 KDENIMNSMQLFENVI 256 KDENIM SMQLFENVI Sbjct: 214 KDENIMRSMQLFENVI 229 >1S1E-A nrPDB Length = 224 Score = 309 bits (792), Expect = 6e-85, Method: Compositional matrix adjust. Identities = 136/196 (69%), Positives = 172/196 (87%) Query: 61 DSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQ 120 D + ELE++ V H+PEGL+QL+AQT FTK+ELQ LYRGFKNECP+G+V+E+TFK IY+Q Sbjct: 21 DKIEDELEMTMVCHRPEGLEQLEAQTNFTKRELQVLYRGFKNECPSGVVNEETFKQIYAQ 80 Query: 121 FFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDG 180 FFP GDA+TYAH+LFNAFD G++ FEDFV LSILLRGTVHEKL+W FNLYDINKDG Sbjct: 81 FFPHGDASTYAHYLFNAFDTTQTGSVKFEDFVTALSILLRGTVHEKLRWTFNLYDINKDG 140 Query: 181 CITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQ 240 I KEEM+ I+K+IYDMMG++TYP+L+ED P +HV+ FFQKMD+N+DG+VT+DEFLE+CQ Sbjct: 141 YINKEEMMDIVKAIYDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLESCQ 200 Query: 241 KDENIMNSMQLFENVI 256 +D+NIM S+QLF+NV+ Sbjct: 201 EDDNIMRSLQLFQNVM 216 >1S6C-A nrPDB Length = 183 Score = 300 bits (768), Expect = 4e-82, Method: Compositional matrix adjust. Identities = 131/183 (71%), Positives = 164/183 (89%) Query: 74 HQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHF 133 H+PEGL+QL+AQT FTK+ELQ LYRGFKNECP+G+V+E+TFK IY+QFFP GDA+TYAH+ Sbjct: 1 HRPEGLEQLEAQTNFTKRELQVLYRGFKNECPSGVVNEETFKQIYAQFFPHGDASTYAHY 60 Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS 193 LFNAFD G++ FEDFV LSILLRGTVHEKL+W FNLYDINKDG I KEEM+ I+K+ Sbjct: 61 LFNAFDTTQTGSVKFEDFVTALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKA 120 Query: 194 IYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQLFE 253 IYDMMG++TYP+L+ED P +HV+ FFQKMD+N+DG+VT+DEFLE+CQ+D+NIM S+QLF+ Sbjct: 121 IYDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLESCQEDDNIMRSLQLFQ 180 Query: 254 NVI 256 NV+ Sbjct: 181 NVM 183 >2E6W-A nrPDB Length = 100 Score = 192 bits (489), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 90/96 (93%), Positives = 93/96 (96%) Query: 161 GTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQ 220 GTVHEKLKWAFNLYDINKDG ITKEEMLAIMKSIYDMMGRHTYPILREDAP EHVERFF+ Sbjct: 5 GTVHEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFFE 64 Query: 221 KMDRNQDGVVTIDEFLETCQKDENIMNSMQLFENVI 256 KMDRNQDGVVTI+EFLE CQKDENIM+SMQLFENVI Sbjct: 65 KMDRNQDGVVTIEEFLEACQKDENIMSSMQLFENVI 100 >2LCP-A nrPDB Length = 190 Score = 173 bits (438), Expect = 6e-44, Method: Compositional matrix adjust. Identities = 80/187 (42%), Positives = 123/187 (65%) Query: 70 STVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATT 129 S + +PE +++L +T FT+KE+Q Y+GF +CP+G +D F+ IY QFFP GD T Sbjct: 4 SNSKLKPEVVEELTRKTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGDPTK 63 Query: 130 YAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLA 189 +A F+FN FD + +G I F +F+ LS+ RGT+ EKL+WAF LYD++ DG IT+ EML Sbjct: 64 FATFVFNVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNEMLD 123 Query: 190 IMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSM 249 I+ +IY M+G E+ P + V+R F MD+N DG +T+ EF E + D +I+ ++ Sbjct: 124 IVDAIYQMVGNTVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIVQAL 183 Query: 250 QLFENVI 256 L++ ++ Sbjct: 184 SLYDGLV 190 >2L2E-A nrPDB Length = 190 Score = 166 bits (420), Expect = 9e-42, Method: Compositional matrix adjust. Identities = 77/180 (42%), Positives = 121/180 (67%), Gaps = 3/180 (1%) Query: 80 DQLQ---AQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFN 136 DQLQ T+F KKELQ Y+GF +CP+G +++ F+ IY QFFP GD + +A ++FN Sbjct: 11 DQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFN 70 Query: 137 AFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYD 196 FDAD NG I F++F+ LS+ RG +++KL WAF LYD++ +G I+ +EML I+ +IY Sbjct: 71 VFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYK 130 Query: 197 MMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQLFENVI 256 M+G ED P + V + F MD+N+DG +T++EF E ++D I++++ L++ ++ Sbjct: 131 MVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVSALSLYDGLV 190 >2JU0-A nrPDB Length = 190 Score = 161 bits (407), Expect = 3e-40, Method: Compositional matrix adjust. Identities = 79/186 (42%), Positives = 115/186 (61%) Query: 71 TVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTY 130 T + + L L+ T F ++E+Q ++GF +CP+G + + F IY QFFP G + Sbjct: 5 TSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDF 64 Query: 131 AHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAI 190 A+ LF FD D NG IHFE+F+ LS RGT+ EKL WAF LYD+N DG IT +EML I Sbjct: 65 ANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTI 124 Query: 191 MKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQ 250 + S+Y MMG E P V++ F+ MD+N+DG +T+DEF E + D +I+ ++ Sbjct: 125 VASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSIIGALN 184 Query: 251 LFENVI 256 L++ +I Sbjct: 185 LYDGLI 190 >5T7C-A nrPDB Length = 193 Score = 157 bits (398), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 71/176 (40%), Positives = 114/176 (64%) Query: 75 QPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFL 134 +PE L L+ T+FT ELQ Y+GF +CPTG + D FK IY+ FFP GDA+ +A + Sbjct: 9 RPEVLQDLRENTEFTDHELQEWYKGFLKDCPTGHLTVDEFKKIYANFFPYGDASKFAEHV 68 Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSI 194 F FD +G+G I F +F++ LS+ RG + +KLKWAF++YD++ +G I++ EML I+++I Sbjct: 69 FRTFDTNGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRSEMLEIVQAI 128 Query: 195 YDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQ 250 Y M+ E P + ++ F++MD N DG ++++EF+ + D +I+ +Q Sbjct: 129 YKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVRLLQ 184 >5M6C-E nrPDB Length = 193 Score = 157 bits (397), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 70/176 (39%), Positives = 116/176 (65%) Query: 75 QPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFL 134 +PE L L+ T+F++ ELQ Y+GF +CPTG+++ D FK IY+ FFP GDA+ +A + Sbjct: 9 RPEMLQDLRENTEFSELELQEWYKGFLKDCPTGILNVDEFKKIYANFFPYGDASKFAEHV 68 Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSI 194 F FD + +G I F +F++ LS+ RG + +KL WAF++YD++ +G I++EEML I+++I Sbjct: 69 FRNFDTNSDGTIDFREFIIALSVTSRGRLEQKLMWAFSMYDLDGNGYISREEMLEIVQAI 128 Query: 195 YDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQ 250 Y M+ E P + E+ F++MD N DG ++++EF+ + D +I+ +Q Sbjct: 129 YKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVRLLQ 184 >1BJF-A nrPDB Length = 193 Score = 155 bits (393), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 70/176 (39%), Positives = 114/176 (64%) Query: 75 QPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFL 134 +PE + L T FT+ E+Q Y+GF +CP+G + + FK IY FFP GDA+ +A + Sbjct: 9 RPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGDASKFAEHV 68 Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSI 194 F FDA+G+G I F +F++ LS+ RG + +KLKWAF++YD++ +G I+K EML I+++I Sbjct: 69 FRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAI 128 Query: 195 YDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQ 250 Y M+ E P + E+ F++MD N+DG ++++EF+ + D +I+ +Q Sbjct: 129 YKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLLQ 184 >6EPA-A nrPDB Length = 187 Score = 155 bits (391), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 73/173 (42%), Positives = 111/173 (64%), Gaps = 1/173 (0%) Query: 79 LDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAF 138 +D+L T FT+KE++ ++GF +CP GL+ E F IY QFFP GD + +A +F F Sbjct: 13 IDRLTTDTYFTEKEIRQWHKGFLKDCPNGLLTEQGFIKIYKQFFPDGDPSKFASLVFRVF 72 Query: 139 DADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMM 198 D + +GAI FE+F+ LSI RG + EKL WAF LYD++ DG IT+EEM I+ +IY M+ Sbjct: 73 DENNDGAIEFEEFIRALSITSRGNLDEKLHWAFRLYDVDNDGYITREEMYNIVDAIYQMV 132 Query: 199 GRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQL 251 G+ E+ P + V++ F +MD+N D +T++EF E + D ++ ++ L Sbjct: 133 GQQP-QTEDENTPQKRVDKIFDQMDKNHDDRLTLEEFREGSKADPRMVQALSL 184 >2I94-A nrPDB Length = 202 Score = 132 bits (332), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 64/177 (36%), Positives = 107/177 (60%), Gaps = 2/177 (1%) Query: 77 EGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFN 136 E L++LQ TKFT++EL S Y+ F ECP+G + F+ IYS+FFP+ D YA +F Sbjct: 12 EILEELQLNTKFTEEELSSWYQSFLKECPSGRITRQEFQTIYSKFFPEADPKAYAQHVFR 71 Query: 137 AFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYD 196 +FDA+ +G + F+++V+ L + G ++KL+WAF+LYD++ +G I+K E+L I+ +I+ Sbjct: 72 SFDANSDGTLDFKEYVIALHMTSAGKTNQKLEWAFSLYDVDGNGTISKNEVLEIVTAIFK 131 Query: 197 MMGRHTYPILRED--APLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQL 251 M+ L ED P + E+ + + D +T EF+E ++ I+ +Q Sbjct: 132 MISPEDTKHLPEDENTPEKRAEKIWGFFGKKDDDKLTEKEFIEGTLANKEILRLIQF 188 >2D8N-A nrPDB Length = 207 Score = 128 bits (322), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 61/177 (34%), Positives = 110/177 (62%), Gaps = 2/177 (1%) Query: 77 EGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFN 136 E L++LQ TKF+++EL S Y+ F +CPTG + + F+ IY++FFP D YA +F Sbjct: 19 EILEELQLNTKFSEEELCSWYQSFLKDCPTGRITQQQFQSIYAKFFPDTDPKAYAQHVFR 78 Query: 137 AFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYD 196 +FD++ +G + F+++V+ L + G ++KL+WAF+LYD++ +G I+K E+L I+ +I+ Sbjct: 79 SFDSNLDGTLDFKEYVIALHMTTAGKTNQKLEWAFSLYDVDGNGTISKNEVLEIVMAIFK 138 Query: 197 MMGRHTYPILRED--APLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQL 251 M+ +L +D P + E+ ++ +N D +T EF+E ++ I+ +Q Sbjct: 139 MITPEDVKLLPDDENTPEKRAEKIWKYFGKNDDDKLTEKEFIEGTLANKEILRLIQF 195 >1JBA-A nrPDB Length = 204 Score = 116 bits (291), Expect = 9e-27, Method: Compositional matrix adjust. Identities = 61/168 (36%), Positives = 100/168 (59%), Gaps = 12/168 (7%) Query: 92 ELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGD---ATTYAHFLFNAFDADGNGAIHF 148 +LQ Y+ F ECP+G + FK +FF D AT Y +F AFD +G+ I F Sbjct: 23 QLQEWYKKFLEECPSGTLFMHEFK----RFFKVPDNEEATQYVEAMFRAFDTNGDNTIDF 78 Query: 149 EDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILRE 208 ++V L+++LRGT+ KLKW F +YD +++GCI ++E+L I++SIY + + + E Sbjct: 79 LEYVAALNLVLRGTLEHKLKWTFKIYDKDRNGCIDRQELLDIVESIYKLKKACSVEVEAE 138 Query: 209 D-----APLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQL 251 P E V+R F +D N DG ++++EF+E ++D+ +M +Q+ Sbjct: 139 QQGKLLTPEEVVDRIFLLVDENGDGQLSLNEFVEGARRDKWVMKMLQM 186 >2R2I-A nrPDB Length = 198 Score = 98.6 bits (244), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 55/167 (32%), Positives = 91/167 (54%), Gaps = 5/167 (2%) Query: 83 QAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADG 142 +A + + E Y+ F ECP+G + FK + A Y +F FD + Sbjct: 6 KAVEELSATECHQWYKKFMTECPSGQLTLYEFKQFFGLKNLSPSANKYVEQMFETFDFNK 65 Query: 143 NGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHT 202 +G I F ++V LS++L+G V +KL+W F LYD++ +GCI + E+L I+K+I + R Sbjct: 66 DGYIDFMEYVAALSLVLKGKVDQKLRWYFKLYDVDGNGCIDRGELLNIIKAIR-AINRCN 124 Query: 203 YPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSM 249 + E E F K+D N DG ++++EF+E QKDE +++ + Sbjct: 125 EAMTAE----EFTNMVFDKIDINGDGELSLEEFMEGVQKDEVLLDIL 167 >2NA0-A nrPDB Length = 205 Score = 97.4 bits (241), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 54/170 (31%), Positives = 96/170 (56%), Gaps = 18/170 (10%) Query: 87 KFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGD----ATTYAHFLFNAFDADG 142 + + E Y+ F ECP+G + F+ QFF + A+ Y +F FD + Sbjct: 12 ELSSTECHQWYKKFMTECPSGQLTLYEFR----QFFGLKNLSPWASQYVEQMFETFDFNK 67 Query: 143 NGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHT 202 +G I F ++ LS++L+G V +KL+W F LYD++ +GCI ++E+L I+++I R Sbjct: 68 DGYIDFMEYEAALSLVLKGKVEQKLRWYFKLYDVDGNGCIDRDELLTIIRAI-----RAI 122 Query: 203 YPILREDAPL---EHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSM 249 P D+ + E + F K+D N DG ++++EF+E QKD+ +++++ Sbjct: 123 NPC--SDSTMTAEEFTDTVFSKIDVNGDGELSLEEFMEGVQKDQMLLDTL 170 >2GGZ-A nrPDB Length = 211 Score = 84.3 bits (207), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 48/173 (27%), Positives = 86/173 (49%), Gaps = 6/173 (3%) Query: 74 HQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHF 133 H G Q +E YR F E P+GL FK + A + Sbjct: 2 HMGNGKSIAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQ 61 Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS 193 ++N FD + +G + F +F+ ++++++ + +KLKW F LYD + +G I K E+L + + Sbjct: 62 VYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMA 121 Query: 194 IYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIM 246 + + G+ T +P E + F K+D N DG +T++EF+ KD++++ Sbjct: 122 VQALNGQQTL------SPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLL 168 >1V1G-A nrPDB Length = 222 Score = 79.3 bits (194), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 54/175 (30%), Positives = 92/175 (52%), Gaps = 11/175 (6%) Query: 82 LQAQTKFTKKELQSLYRGFKNECPT----GLVDEDTFKLIYSQFFPQGDATTYAHFLFNA 137 L + T FT +E+++LY FK + GL+ ++ F+L + F + +A +F+ Sbjct: 25 LASVTPFTVEEVEALYELFKKLSSSIIDDGLIHKEEFQL--ALFRNRNRRNLFADRIFDV 82 Query: 138 FDADGNGAIHFEDFVVGLSIL-LRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYD 196 FD NG I F +FV L + VHEK+K+AF LYD+ + G I +EE +K + Sbjct: 83 FDVKRNGVIEFGEFVRSLGVFHPSAPVHEKVKFAFKLYDLRQTGFIEREE----LKEMVV 138 Query: 197 MMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQL 251 + + +L ED V++ F + DR DG + IDE+ + + +++ +M L Sbjct: 139 ALLHESELVLSEDMIEVMVDKAFVQADRKNDGKIDIDEWKDFVSLNPSLIKNMTL 193 >5YPX-A nrPDB Length = 223 Score = 78.6 bits (192), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 55/180 (30%), Positives = 91/180 (50%), Gaps = 10/180 (5%) Query: 56 APQGSDSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFK 115 P+GS S +L+ E L + Q FTK E++SL +KN +D + F+ Sbjct: 15 VPRGSHMSKKNQKLA------EELYKTSCQKHFTKTEVESLIICYKNLLEGLKMDRNLFR 68 Query: 116 LIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYD 175 I Q F + +F AFD D + I ++V GLS+ LRGT+ EK+++ F ++D Sbjct: 69 DILHQKFNMTEDLLMDR-VFRAFDKDSDSYISLTEWVEGLSVFLRGTLDEKMEYTFTVFD 127 Query: 176 INKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEF 235 +N DG I++EEM ++K+ P ++ + VE +KMD + D ++ +F Sbjct: 128 LNGDGYISREEMFQMLKTCLVKQPTEEDP---DEGIKDLVEIALKKMDHDHDSRLSKKDF 184 >5B8I-B nrPDB Length = 171 Score = 64.7 bits (156), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 45/166 (27%), Positives = 86/166 (51%), Gaps = 17/166 (10%) Query: 79 LDQLQAQTKFTKKELQSLYRGFK--NECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFN 136 L+ + + + F +E+ L++ F + +G ++ D F + PQ + + + Sbjct: 6 LNDIVSGSNFDHEEVDRLWKRFMKLDRDKSGTIERDEFLSL-----PQVSSNPLSTRMIA 60 Query: 137 AFDADGNGAIHFEDFVVGLSILL-RGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIY 195 FD DG G + F++FV GLS +G EKL++AF +YDI++DG I+ E+ ++K Sbjct: 61 IFDEDGGGDVDFQEFVSGLSAFSSKGNKEEKLRFAFKVYDIDRDGFISNGELFIVLKM-- 118 Query: 196 DMMGRHTYPILREDAPLEH-VERFFQKMDRNQDGVVTIDEFLETCQ 240 M+G + +D L+ V++ + D + DG ++ +EF + Sbjct: 119 -MVGSNL-----KDMQLQQIVDKTIMEADLDGDGRISFEEFTRMVE 158 >4IL1-A nrPDB Length = 823 Score = 60.5 bits (145), Expect = 8e-10, Method: Compositional matrix adjust. Identities = 42/157 (26%), Positives = 83/157 (52%), Gaps = 15/157 (9%) Query: 82 LQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQF--FPQGDATTYAHFLFNAFD 139 L+ + F E++ L + FK L +++ L +F P+ + + FD Sbjct: 166 LEMCSHFDADEIKRLGKRFKK-----LDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFD 220 Query: 140 ADGNGAIHFEDFVVGLS-ILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMM 198 DGNG + F++F+ G+S ++G +KL++AF +YD++KDG I+ E+ ++K M+ Sbjct: 221 TDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKM---MV 277 Query: 199 GRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEF 235 G + L++ + V++ D++ DG ++ +EF Sbjct: 278 GNN----LKDTQLQQIVDKTIINADKDGDGRISFEEF 310 Score = 47.0 bits (110), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 30/105 (28%), Positives = 53/105 (50%), Gaps = 13/105 (12%) Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKDGCITKEEMLAIMK 192 + N DADGNG I F +F+ ++ ++ T E+++ AF ++D + +G I+ E+ Sbjct: 52 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL----- 106 Query: 193 SIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLE 237 RH L E E V+ ++ D + DG V +EF++ Sbjct: 107 -------RHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQ 144 Score = 34.7 bits (78), Expect = 0.046, Method: Compositional matrix adjust. Identities = 35/166 (21%), Positives = 69/166 (41%), Gaps = 11/166 (6%) Query: 89 TKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHF 148 T+ ELQ + + G +D F + ++ D+ F FD DGNG I Sbjct: 45 TEAELQDMINEVDADG-NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISA 103 Query: 149 EDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS------IYDMMGRHT 202 + ++ L E++ DI+ DG + EE + +M + + Sbjct: 104 AELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAKGGGGGGGGGGNEAS 163 Query: 203 YPI-LREDAPLEHVERF---FQKMDRNQDGVVTIDEFLETCQKDEN 244 YP+ + + ++R F+K+D + G ++++EF+ + +N Sbjct: 164 YPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQN 209 Score = 30.0 bits (66), Expect = 1.0, Method: Compositional matrix adjust. Identities = 18/71 (25%), Positives = 35/71 (49%), Gaps = 12/71 (16%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRN 225 + K AF+L+D + DG IT +E+ +M+S L ++ ++ ++D + Sbjct: 12 EFKEAFSLFDKDGDGTITTKELGTVMRS------------LGQNPTEAELQDMINEVDAD 59 Query: 226 QDGVVTIDEFL 236 +G + EFL Sbjct: 60 GNGTIDFPEFL 70 >4ORC-B nrPDB Length = 170 Score = 60.1 bits (144), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 33/115 (28%), Positives = 65/115 (56%), Gaps = 8/115 (6%) Query: 122 FPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLS-ILLRGTVHEKLKWAFNLYDINKDG 180 P+ + + FD DGNG + F++F+ G+S ++G +KL++AF +YD++KDG Sbjct: 46 LPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDG 105 Query: 181 CITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEF 235 I+ E+ ++K M+G + L++ + V++ D++ DG ++ +EF Sbjct: 106 YISNGELFQVLKM---MVGNN----LKDTQLQQIVDKTIINADKDGDGRISFEEF 153 >1UHN-A nrPDB Length = 189 Score = 58.5 bits (140), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 42/175 (24%), Positives = 87/175 (49%), Gaps = 11/175 (6%) Query: 82 LQAQTKFTKKELQSLYRGFKNECPT----GLVDEDTFKLIYSQFFPQGDATTYAHFLFNA 137 L T F+ E+++LY FK GL++++ F+L + F + +A +F+ Sbjct: 5 LARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQL--ALFKTNKKESLFADRVFDL 62 Query: 138 FDADGNGAIHFEDFVVGLSILL-RGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYD 196 FD NG + FE+F LS+ + +K+ ++F LYD+ + G I ++E+ ++ + Sbjct: 63 FDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLA 122 Query: 197 MMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQL 251 G + + ED +++ F++ D DG + +E+ + +++ +M L Sbjct: 123 ESGMNLKDTVIEDI----IDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTL 173 >2ZFD-A nrPDB Length = 226 Score = 58.5 bits (140), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 42/175 (24%), Positives = 87/175 (49%), Gaps = 11/175 (6%) Query: 82 LQAQTKFTKKELQSLYRGFKNECPT----GLVDEDTFKLIYSQFFPQGDATTYAHFLFNA 137 L T F+ E+++LY FK GL++++ F+L + F + +A +F+ Sbjct: 36 LARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQL--ALFKTNKKESLFADRVFDL 93 Query: 138 FDADGNGAIHFEDFVVGLSILL-RGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYD 196 FD NG + FE+F LS+ + +K+ ++F LYD+ + G I ++E+ ++ + Sbjct: 94 FDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLA 153 Query: 197 MMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQL 251 G + + ED +++ F++ D DG + +E+ + +++ +M L Sbjct: 154 ESGMNLKDTVIEDI----IDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTL 204 >2TN4-A nrPDB Length = 159 Score = 51.6 bits (122), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 33/111 (29%), Positives = 52/111 (46%), Gaps = 16/111 (14%) Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLR----GTVHEKLKWAFNLYDINKDGCITKEEMLA 189 + D DG+G I FE+F+V + ++ G E+L F ++D N DG I EE+ Sbjct: 58 IIEEVDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELAELFRIFDRNADGYIDAEELAE 117 Query: 190 IMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQ 240 I ++ G H E +E + D+N DG + DEFL+ + Sbjct: 118 IFRA----SGEHVTD--------EEIESLMKDGDKNNDGRIDFDEFLKMME 156 Score = 27.3 bits (59), Expect = 7.1, Method: Compositional matrix adjust. Identities = 21/72 (29%), Positives = 37/72 (51%), Gaps = 14/72 (19%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILRE-DAPLEHVERFFQKMDR 224 + K AF+++D + G I+ +E+ +M+ M+G+ P E DA +E V D Sbjct: 18 EFKAAFDMFDADGGGDISVKELGTVMR----MLGQ--TPTKEELDAIIEEV-------DE 64 Query: 225 NQDGVVTIDEFL 236 + G + +EFL Sbjct: 65 DGSGTIDFEEFL 76 >2L1W-A nrPDB Length = 149 Score = 50.8 bits (120), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 32/104 (30%), Positives = 55/104 (52%), Gaps = 13/104 (12%) Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKDGCITKEEMLAIMK 192 + + DADGNG I F++F+ ++ ++ T E+LK AF ++D +++G I+ E+ Sbjct: 51 MISEVDADGNGTIEFDEFLSLMAKKVKDTDAEEELKEAFKVFDKDQNGYISASEL----- 105 Query: 193 SIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFL 236 RH L E E VE+ ++ D + DG V +EF+ Sbjct: 106 -------RHVMINLGEKLTDEEVEQMIKEADLDGDGQVNYEEFV 142 Score = 38.5 bits (88), Expect = 0.003, Method: Compositional matrix adjust. Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 12/75 (16%) Query: 167 LKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQ 226 K AF L+D + DGCIT EE+ +++S L ++ E ++ ++D + Sbjct: 12 FKEAFGLFDKDGDGCITVEELATVIRS------------LDQNPTEEELQDMISEVDADG 59 Query: 227 DGVVTIDEFLETCQK 241 +G + DEFL K Sbjct: 60 NGTIEFDEFLSLMAK 74 Score = 28.1 bits (61), Expect = 3.4, Method: Compositional matrix adjust. Identities = 24/106 (22%), Positives = 45/106 (42%), Gaps = 1/106 (0%) Query: 89 TKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHF 148 T++ELQ + + G ++ D F + ++ DA F FD D NG I Sbjct: 44 TEEELQDMISEVDAD-GNGTIEFDEFLSLMAKKVKDTDAEEELKEAFKVFDKDQNGYISA 102 Query: 149 EDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSI 194 + + L E+++ D++ DG + EE + +M ++ Sbjct: 103 SELRHVMINLGEKLTDEEVEQMIKEADLDGDGQVNYEEFVKMMMTV 148 >1TOP-A nrPDB Length = 162 Score = 50.8 bits (120), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 33/106 (31%), Positives = 52/106 (49%), Gaps = 16/106 (15%) Query: 139 DADGNGAIHFEDFVVGLSILLR----GTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSI 194 D DG+G I FE+F+V + ++ G E+L F ++D N DG I EE+ I+++ Sbjct: 66 DEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELANCFRIFDKNADGFIDIEELGEILRAT 125 Query: 195 YDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQ 240 G H E +E + D+N DG + DEFL+ + Sbjct: 126 ----GEHVTE--------EDIEDLMKDSDKNNDGRIDFDEFLKMME 159 Score = 28.5 bits (62), Expect = 2.7, Method: Compositional matrix adjust. Identities = 16/71 (22%), Positives = 37/71 (52%), Gaps = 12/71 (16%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRN 225 + K AF+++D + G I+ +E+ +M+ M+G++ E ++ +++D + Sbjct: 21 EFKAAFDMFDADGGGDISTKELGTVMR----MLGQNPTK--------EELDAIIEEVDED 68 Query: 226 QDGVVTIDEFL 236 G + +EFL Sbjct: 69 GSGTIDFEEFL 79 >2N6A-A nrPDB Length = 173 Score = 48.1 bits (113), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 30/105 (28%), Positives = 53/105 (50%), Gaps = 13/105 (12%) Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKDGCITKEEMLAIMK 192 + N DADGNG I F +F+ ++ ++ T E+++ AF ++D + +G I+ E+ Sbjct: 53 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL----- 107 Query: 193 SIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLE 237 RH L E E V+ ++ D + DG V +EF++ Sbjct: 108 -------RHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQ 145 Score = 30.4 bits (67), Expect = 0.78, Method: Compositional matrix adjust. Identities = 20/72 (27%), Positives = 38/72 (52%), Gaps = 14/72 (19%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLE-HVERFFQKMDR 224 + K AF+L+D + DG IT +E+ +M+S +G++ P E ++ ++D Sbjct: 13 EFKEAFSLFDKDGDGTITTKELGTVMRS----LGQN---------PTEAELQDMINEVDA 59 Query: 225 NQDGVVTIDEFL 236 + +G + EFL Sbjct: 60 DGNGTIDFPEFL 71 Score = 30.0 bits (66), Expect = 1.1, Method: Compositional matrix adjust. Identities = 27/106 (25%), Positives = 43/106 (40%), Gaps = 7/106 (6%) Query: 89 TKKELQSLYRGFKNECPT---GLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGA 145 T+ ELQ + NE G +D F + ++ D+ F FD DGNG Sbjct: 46 TEAELQDMI----NEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGY 101 Query: 146 IHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIM 191 I + ++ L E++ DI+ DG + EE + +M Sbjct: 102 ISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 147 >5A2H-A nrPDB Length = 149 Score = 48.1 bits (113), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 31/104 (29%), Positives = 53/104 (50%), Gaps = 13/104 (12%) Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKDGCITKEEMLAIMK 192 + N DADGNG I F +F+ ++ ++ T E+LK AF ++D +++G I+ E+ Sbjct: 52 MINEVDADGNGTIDFPEFLNLMARKMKDTDSEEELKEAFRVFDKDQNGFISAAEL----- 106 Query: 193 SIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFL 236 RH L E E V+ ++ D + DG + +EF+ Sbjct: 107 -------RHVMTNLGEKLTDEEVDEMIREADVDGDGQINYEEFV 143 Score = 33.9 bits (76), Expect = 0.067, Method: Compositional matrix adjust. Identities = 13/29 (44%), Positives = 22/29 (75%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSI 194 + K AF+L+D + DGCIT +E+ +M+S+ Sbjct: 12 EFKEAFSLFDKDGDGCITTKELGTVMRSL 40 >5I0I-E nrPDB Length = 145 Score = 47.8 bits (112), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 30/105 (28%), Positives = 53/105 (50%), Gaps = 13/105 (12%) Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKDGCITKEEMLAIMK 192 + N DADGNG I F +F+ ++ ++ T E+++ AF ++D + +G I+ E+ Sbjct: 50 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL----- 104 Query: 193 SIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLE 237 RH L E E V+ ++ D + DG V +EF++ Sbjct: 105 -------RHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQ 142 Score = 30.0 bits (66), Expect = 1.0, Method: Compositional matrix adjust. Identities = 25/103 (24%), Positives = 42/103 (40%), Gaps = 1/103 (0%) Query: 89 TKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHF 148 T+ ELQ + + G +D F + ++ D+ F FD DGNG I Sbjct: 43 TEAELQDMINEVDADG-NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISA 101 Query: 149 EDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIM 191 + ++ L E++ DI+ DG + EE + +M Sbjct: 102 AELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 144 Score = 28.9 bits (63), Expect = 2.2, Method: Compositional matrix adjust. Identities = 12/29 (41%), Positives = 20/29 (68%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSI 194 + K AF+L D + DG IT +E+ +M+S+ Sbjct: 10 EFKEAFSLADKDGDGTITTKELGTVMRSL 38 >4E53-A nrPDB Length = 185 Score = 47.8 bits (112), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 30/105 (28%), Positives = 53/105 (50%), Gaps = 13/105 (12%) Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKDGCITKEEMLAIMK 192 + N DADGNG I F +F+ ++ ++ T E+++ AF ++D + +G I+ E+ Sbjct: 59 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL----- 113 Query: 193 SIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLE 237 RH L E E V+ ++ D + DG V +EF++ Sbjct: 114 -------RHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQ 151 Score = 30.4 bits (67), Expect = 0.74, Method: Compositional matrix adjust. Identities = 12/29 (41%), Positives = 21/29 (72%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSI 194 + K AF+L+D + DG IT +E+ +M+S+ Sbjct: 19 EFKEAFSLFDKDGDGTITTKELGTVMRSL 47 Score = 30.0 bits (66), Expect = 1.1, Method: Compositional matrix adjust. Identities = 27/106 (25%), Positives = 43/106 (40%), Gaps = 7/106 (6%) Query: 89 TKKELQSLYRGFKNECPT---GLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGA 145 T+ ELQ + NE G +D F + ++ D+ F FD DGNG Sbjct: 52 TEAELQDMI----NEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGY 107 Query: 146 IHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIM 191 I + ++ L E++ DI+ DG + EE + +M Sbjct: 108 ISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 153 >2F2P-A nrPDB Length = 179 Score = 47.8 bits (112), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 30/105 (28%), Positives = 53/105 (50%), Gaps = 13/105 (12%) Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKDGCITKEEMLAIMK 192 + N DADGNG I F +F+ ++ ++ T E+++ AF ++D + +G I+ E+ Sbjct: 52 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL----- 106 Query: 193 SIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLE 237 RH L E E V+ ++ D + DG V +EF++ Sbjct: 107 -------RHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQ 144 Score = 30.4 bits (67), Expect = 0.80, Method: Compositional matrix adjust. Identities = 27/108 (25%), Positives = 44/108 (40%), Gaps = 7/108 (6%) Query: 89 TKKELQSLYRGFKNECPT---GLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGA 145 T+ ELQ + NE G +D F + ++ D+ F FD DGNG Sbjct: 45 TEAELQDMI----NEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGY 100 Query: 146 IHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS 193 I + ++ L E++ DI+ DG + EE + +M + Sbjct: 101 ISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 148 Score = 30.4 bits (67), Expect = 0.85, Method: Compositional matrix adjust. Identities = 12/29 (41%), Positives = 21/29 (72%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSI 194 + K AF+L+D + DG IT +E+ +M+S+ Sbjct: 12 EFKEAFSLFDKDGDGTITTKELGTVMRSL 40 >6O20-F nrPDB Length = 169 Score = 47.8 bits (112), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 30/105 (28%), Positives = 53/105 (50%), Gaps = 13/105 (12%) Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKDGCITKEEMLAIMK 192 + N DADGNG I F +F+ ++ ++ T E+++ AF ++D + +G I+ E+ Sbjct: 72 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL----- 126 Query: 193 SIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLE 237 RH L E E V+ ++ D + DG V +EF++ Sbjct: 127 -------RHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQ 164 Score = 30.8 bits (68), Expect = 0.65, Method: Compositional matrix adjust. Identities = 12/29 (41%), Positives = 21/29 (72%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSI 194 + K AF+L+D + DG IT +E+ +M+S+ Sbjct: 32 EFKEAFSLFDKDGDGTITTKELGTVMRSL 60 Score = 30.0 bits (66), Expect = 0.95, Method: Compositional matrix adjust. Identities = 25/105 (23%), Positives = 43/105 (40%), Gaps = 1/105 (0%) Query: 89 TKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHF 148 T+ ELQ + + G +D F + ++ D+ F FD DGNG I Sbjct: 65 TEAELQDMINEVDADG-NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISA 123 Query: 149 EDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS 193 + ++ L E++ DI+ DG + EE + +M + Sbjct: 124 AELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 168 >1DTL-A nrPDB Length = 161 Score = 47.4 bits (111), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 31/108 (28%), Positives = 54/108 (50%), Gaps = 16/108 (14%) Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLR----GTVHEKLKWAFNLYDINKDGCITKEEMLA 189 + + D DG+G + F++F+V + ++ G E+L F ++D N DG I EE+ Sbjct: 60 MIDEVDEDGSGTVDFDEFLVMMVRSMKDDSKGKSEEELSDLFRMFDKNADGYIDLEELKI 119 Query: 190 IMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLE 237 ++++ T + ED +E + D+N DG + DEFLE Sbjct: 120 MLQA--------TGETITED----DIEELMKDGDKNNDGRIDYDEFLE 155 >3WFN-B nrPDB Length = 182 Score = 47.4 bits (111), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 30/105 (28%), Positives = 53/105 (50%), Gaps = 13/105 (12%) Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKDGCITKEEMLAIMK 192 + N DADGNG I F +F+ ++ ++ T E+++ AF ++D + +G I+ E+ Sbjct: 58 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL----- 112 Query: 193 SIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLE 237 RH L E E V+ ++ D + DG V +EF++ Sbjct: 113 -------RHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQ 150 Score = 31.6 bits (70), Expect = 0.39, Method: Compositional matrix adjust. Identities = 31/132 (23%), Positives = 52/132 (39%), Gaps = 7/132 (5%) Query: 89 TKKELQSLYRGFKNECPT---GLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGA 145 T+ ELQ + NE G +D F + ++ D+ F FD DGNG Sbjct: 51 TEAELQDMI----NEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGY 106 Query: 146 IHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPI 205 I + ++ L E++ DI+ DG + EE + +M + G + Sbjct: 107 ISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAKGGGGGEEVSAV 166 Query: 206 LREDAPLEHVER 217 + + A H+ R Sbjct: 167 VLQRAYRGHLAR 178 Score = 30.8 bits (68), Expect = 0.55, Method: Compositional matrix adjust. Identities = 12/29 (41%), Positives = 21/29 (72%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSI 194 + K AF+L+D + DG IT +E+ +M+S+ Sbjct: 18 EFKEAFSLFDKDGDGTITTKELGTVMRSL 46 >3EK4-A nrPDB Length = 451 Score = 47.4 bits (111), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 30/105 (28%), Positives = 53/105 (50%), Gaps = 13/105 (12%) Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKDGCITKEEMLAIMK 192 + N DADGNG I F +F+ ++ ++ T E+++ AF ++D + +G I+ E+ Sbjct: 354 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL----- 408 Query: 193 SIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLE 237 RH L E E V+ ++ D + DG V +EF++ Sbjct: 409 -------RHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQ 446 Score = 30.8 bits (68), Expect = 0.54, Method: Compositional matrix adjust. Identities = 18/71 (25%), Positives = 35/71 (49%), Gaps = 12/71 (16%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRN 225 + K AF+L+D + DG IT +E+ +M+S L ++ ++ ++D + Sbjct: 314 EFKEAFSLFDKDGDGTITTKELGTVMRS------------LGQNPTEAELQDMINEVDAD 361 Query: 226 QDGVVTIDEFL 236 +G + EFL Sbjct: 362 GNGTIDFPEFL 372 Score = 28.9 bits (63), Expect = 2.2, Method: Compositional matrix adjust. Identities = 25/105 (23%), Positives = 43/105 (40%), Gaps = 1/105 (0%) Query: 89 TKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHF 148 T+ ELQ + + G +D F + ++ D+ F FD DGNG I Sbjct: 347 TEAELQDMINEVDADG-NGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISA 405 Query: 149 EDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS 193 + ++ L E++ DI+ DG + EE + +M + Sbjct: 406 AELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 450 >4JWQ-A nrPDB Length = 199 Score = 47.0 bits (110), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 32/105 (30%), Positives = 58/105 (55%), Gaps = 10/105 (9%) Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKW-AFNLYDINKDGCITKEEMLAIMK 192 L + D+DG+G I + +F+ + L R + +KL + AF ++D++ DG IT E+ I+ Sbjct: 98 LLDQIDSDGSGRIDYTEFLA--AALDRKHLSKKLIYCAFRVFDVDNDGEITTAELAHILY 155 Query: 193 SIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLE 237 + G I ++D + V++ Q++D+N DG + EF E Sbjct: 156 N-----GNKKGSITQKD--VNQVKKMIQEVDKNNDGKIDFYEFCE 193 >3K21-A nrPDB Length = 191 Score = 47.0 bits (110), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 32/109 (29%), Positives = 57/109 (52%), Gaps = 10/109 (9%) Query: 133 FLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKW-AFNLYDINKDGCITKEEMLAIM 191 L + D+DG+G I + +F+ + L R + +KL + AF ++D++ DG IT E+ I+ Sbjct: 91 LLLDQIDSDGSGKIDYTEFIA--AALDRKQLSKKLIYCAFRVFDVDNDGEITTAELAHIL 148 Query: 192 KSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQ 240 + G I + D + V+R + +D+N DG + EF E + Sbjct: 149 YN-----GNKKGNITQRD--VNRVKRMIRDVDKNNDGKIDFHEFSEMMK 190 >3U0K-A nrPDB Length = 442 Score = 46.6 bits (109), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 29/105 (27%), Positives = 54/105 (51%), Gaps = 13/105 (12%) Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKDGCITKEEMLAIMK 192 + N DADG+G I F +F++ ++ ++ T E+++ AF ++D + +G I+ E+ Sbjct: 345 MINEVDADGDGTIDFPEFLIMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL----- 399 Query: 193 SIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLE 237 RH L E E V+ ++ D + DG V +EF++ Sbjct: 400 -------RHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQ 437 Score = 32.7 bits (73), Expect = 0.16, Method: Compositional matrix adjust. Identities = 19/71 (26%), Positives = 35/71 (49%), Gaps = 12/71 (16%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRN 225 + K AF+L+D + DG IT +E+ +M+S L ++ ++ ++D + Sbjct: 305 EFKEAFSLFDKDGDGTITTKELGTVMRS------------LGQNPTEAELQDMINEVDAD 352 Query: 226 QDGVVTIDEFL 236 DG + EFL Sbjct: 353 GDGTIDFPEFL 363 Score = 30.0 bits (66), Expect = 0.94, Method: Compositional matrix adjust. Identities = 27/108 (25%), Positives = 45/108 (41%), Gaps = 7/108 (6%) Query: 89 TKKELQSLYRGFKNECPT---GLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGA 145 T+ ELQ + NE G +D F ++ ++ D+ F FD DGNG Sbjct: 338 TEAELQDMI----NEVDADGDGTIDFPEFLIMMARKMKDTDSEEEIREAFRVFDKDGNGY 393 Query: 146 IHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS 193 I + ++ L E++ DI+ DG + EE + +M + Sbjct: 394 ISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 441 >6HCS-A nrPDB Length = 167 Score = 46.2 bits (108), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 30/105 (28%), Positives = 53/105 (50%), Gaps = 13/105 (12%) Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKDGCITKEEMLAIMK 192 + N DADGNG I F +F+ ++ ++ T E+++ AF ++D + +G I+ E+ Sbjct: 52 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL----- 106 Query: 193 SIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLE 237 RH L E E V+ ++ D + DG V +EF++ Sbjct: 107 -------RHFMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQ 144 Score = 30.8 bits (68), Expect = 0.63, Method: Compositional matrix adjust. Identities = 12/29 (41%), Positives = 21/29 (72%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSI 194 + K AF+L+D + DG IT +E+ +M+S+ Sbjct: 12 EFKEAFSLFDKDGDGTITTKELGTVMRSL 40 Score = 28.9 bits (63), Expect = 2.0, Method: Compositional matrix adjust. Identities = 27/108 (25%), Positives = 44/108 (40%), Gaps = 7/108 (6%) Query: 89 TKKELQSLYRGFKNECPT---GLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGA 145 T+ ELQ + NE G +D F + ++ D+ F FD DGNG Sbjct: 45 TEAELQDMI----NEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGY 100 Query: 146 IHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS 193 I + ++ L E++ DI+ DG + EE + +M + Sbjct: 101 ISAAELRHFMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 148 >3NCG-A nrPDB Length = 486 Score = 46.2 bits (108), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 53/236 (22%), Positives = 93/236 (39%), Gaps = 57/236 (24%) Query: 39 RQALMRCCLIKWI--LSSAAPQGSDSSDSELELSTVRHQPEGLDQLQAQTKFTK------ 90 R +C WI SS P SD E ++ +R Q QA+ K + Sbjct: 268 RITATQCLEHPWIQKYSSETPTISDLPSLESAMTNIR-------QFQAEKKLAQAALLYM 320 Query: 91 ----------KELQSLYRGFKNECPTGLVDEDTFKLIYSQF----------FPQGDATTY 130 K+L ++R G++D D Y +F Q + +T Sbjct: 321 ASKLTTLDETKQLTEIFRKLDTN-NDGMLDRDELVRGYHEFMRLKGVDSNSLIQNEGSTI 379 Query: 131 ---AHFLFNAFDADGNGAIHFEDFV---VGLSILLRGTVHEKLKWAFNLYDINKDGCITK 184 L D DG+G+I + +F+ + +ILL E+++ AF ++D + G I+ Sbjct: 380 EDQIDSLMPLLDMDGSGSIEYSEFIASAIDRTILLS---RERMERAFKMFDKDGSGKIST 436 Query: 185 EEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQ 240 +E+ + + +E +E +++D N+DG V +EF+E Q Sbjct: 437 KELFKL------------FSQADSSIQMEELESIIEQVDNNKDGEVDFNEFVEMLQ 480 >2E30-A nrPDB Length = 195 Score = 45.8 bits (107), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 42/184 (22%), Positives = 86/184 (46%), Gaps = 32/184 (17%) Query: 77 EGLDQLQAQTKFTKKELQSLYRGFK--NECPTGLVDEDTFKLIYSQFFPQGDATTYAHFL 134 E L++++ +T F+ ++ LY F ++ G + + F+ I P+ + Sbjct: 12 EELEEIKKETGFSHSQITRLYSRFTSLDKGENGTLSREDFQRI-----PELAINPLGDRI 66 Query: 135 FNAFDADGNGAIHFEDFVVGLSIL-----------LRG-----TVHEKLKWAFNLYDINK 178 NAF +G ++F F+ L+ + G + KL +AF LYD++K Sbjct: 67 INAFFPEGEDQVNFRGFMRTLAHFRPIEDNEKSKDVNGPEPLNSRSNKLHFAFRLYDLDK 126 Query: 179 DGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHV-ERFFQKMDRNQDGVVTIDEFLE 237 D I+++E+L +++ M+G + D L + +R Q+ D++ D ++ EF++ Sbjct: 127 DEKISRDELLQVLRM---MVGVNI-----SDEQLGSIADRTIQEADQDGDSAISFTEFVK 178 Query: 238 TCQK 241 +K Sbjct: 179 VLEK 182 >2BEC-A nrPDB Length = 202 Score = 45.4 bits (106), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 26/77 (33%), Positives = 47/77 (61%), Gaps = 9/77 (11%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHV-ERFFQKMDR 224 KL +AF LYD+++DG I++ EML +++ M+G + + LE++ +R Q+ D Sbjct: 115 KLHYAFQLYDLDRDGKISRHEMLQVLRL---MVG-----VQVTEEQLENIADRTVQEADE 166 Query: 225 NQDGVVTIDEFLETCQK 241 + DG V+ EF ++ +K Sbjct: 167 DGDGAVSFVEFTKSLEK 183 >1JFJ-A nrPDB Length = 134 Score = 45.1 bits (105), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 34/114 (29%), Positives = 51/114 (44%), Gaps = 29/114 (25%) Query: 132 HFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEK--------LKWAFNLYDINKDGCIT 183 +F + DADGNG I +F G++ + LK + L D++ DG +T Sbjct: 39 QLIFKSIDADGNGEIDQNEFAK-----FYGSIQGQDLSDDKIGLKVLYKLMDVDGDGKLT 93 Query: 184 KEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLE 237 KEE+ + K +H +E V K D N DG +T++EFLE Sbjct: 94 KEEVTSFFK-------KH---------GIEKVAEQVMKADANGDGYITLEEFLE 131 >3QRX-A nrPDB Length = 169 Score = 45.1 bits (105), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 43/168 (25%), Positives = 74/168 (44%), Gaps = 22/168 (13%) Query: 80 DQLQAQTKFTKKELQSLYRGFK--NECPTGLVDEDTFKLIYSQ--FFPQGDATTYAHFLF 135 DQ + + T+++ Q + F + +G +D K+ F P+ + + Sbjct: 14 DQKKGRVGLTEEQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKK---MI 70 Query: 136 NAFDADGNGAIHFEDFVVGLSILL--RGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS 193 + D DG+G I FE+F+ ++ + R + E LK AF L+D + G IT Sbjct: 71 SEIDKDGSGTIDFEEFLTMMTAKMGERDSREEILK-AFRLFDDDNSGTIT---------- 119 Query: 194 IYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 I D+ R L E+ E ++ + DRN D + DEF+ +K Sbjct: 120 IKDL--RRVAKELGENLTEEELQEMIAEADRNDDNEIDEDEFIRIMKK 165 >4OY4-A nrPDB Length = 415 Score = 44.7 bits (104), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 29/105 (27%), Positives = 53/105 (50%), Gaps = 13/105 (12%) Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKDGCITKEEMLAIMK 192 + N DADG+G I F +F+ ++ ++ T E+++ AF ++D + +G I+ E+ Sbjct: 59 MINEVDADGDGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL----- 113 Query: 193 SIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLE 237 RH L E E V+ ++ D + DG V +EF++ Sbjct: 114 -------RHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQ 151 Score = 32.3 bits (72), Expect = 0.23, Method: Compositional matrix adjust. Identities = 19/71 (26%), Positives = 35/71 (49%), Gaps = 12/71 (16%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRN 225 + K AF+L+D + DG IT +E+ +M+S L ++ ++ ++D + Sbjct: 19 EFKEAFSLFDKDGDGTITTKELGTVMRS------------LGQNPTEAELQDMINEVDAD 66 Query: 226 QDGVVTIDEFL 236 DG + EFL Sbjct: 67 GDGTIDFPEFL 77 >5ZOR-A nrPDB Length = 149 Score = 43.5 bits (101), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 31/96 (32%), Positives = 47/96 (48%), Gaps = 18/96 (18%) Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDR 224 E+++ AFNL+D + G I EEM MK + G D P + VER + M+ Sbjct: 7 EQIREAFNLFDADGSGAIDAEEMALAMKGLG--FG---------DLPRDEVERTVRSMNT 55 Query: 225 NQDGVVTIDEF-----LETCQKD--ENIMNSMQLFE 253 N +G++ EF QKD E ++ + QLF+ Sbjct: 56 NANGLIEYGEFERMVKSRMAQKDSPEEVLKAFQLFD 91 Score = 33.9 bits (76), Expect = 0.067, Method: Compositional matrix adjust. Identities = 28/107 (26%), Positives = 51/107 (47%), Gaps = 12/107 (11%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTV-HEKLKWAFNLYDINKDGCITKEEMLAIMKS 193 FN FDADG+GAI E+ + + L G + ++++ + N +G I E ++KS Sbjct: 13 FNLFDADGSGAIDAEEMALAMKGLGFGDLPRDEVERTVRSMNTNANGLIEYGEFERMVKS 72 Query: 194 IYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQ 240 + ++D+P E V + FQ D ++ G ++ E + Sbjct: 73 ----------RMAQKDSP-EEVLKAFQLFDLDKKGKISFANLKEVAK 108 >2JNF-A nrPDB Length = 158 Score = 42.4 bits (98), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 39/151 (25%), Positives = 65/151 (43%), Gaps = 18/151 (11%) Query: 91 KELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFED 150 K L++ +R F+ +G V D +I Q +T L + FD GNG I F+ Sbjct: 13 KLLETAFRDFETPEGSGRVSTDQIGIILEVLGIQQTKSTIRQ-LIDEFDPFGNGDIDFDS 71 Query: 151 F-VVGLSILLRGT----VHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPI 205 F ++G L + ++L+ AF LYD +G I+ + M I+ Sbjct: 72 FKIIGARFLGEEVNPEQMQQELREAFRLYDKEGNGYISTDVMREILAE------------ 119 Query: 206 LREDAPLEHVERFFQKMDRNQDGVVTIDEFL 236 L E E ++ ++D + G V +EF+ Sbjct: 120 LDETLSSEDLDAMIDEIDADGSGTVDFEEFM 150 >1SNL-A nrPDB Length = 103 Score = 42.0 bits (97), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 26/80 (32%), Positives = 43/80 (53%), Gaps = 4/80 (5%) Query: 168 KWAFNLYDINKDGCITKEEMLAI----MKSIYDMMGRHTYPILREDAPLEHVERFFQKMD 223 K F L+DIN DG + ++E+ A+ ++ +YD E+ L E + +D Sbjct: 23 KTFFILHDINSDGVLDEQELEALFTKELEKVYDPKNEEDDMREMEEERLRMREHVMKNVD 82 Query: 224 RNQDGVVTIDEFLETCQKDE 243 NQD +VT++EFL + Q+ E Sbjct: 83 TNQDRLVTLEEFLASTQRKE 102 >1CLM-A nrPDB Length = 148 Score = 42.0 bits (97), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 31/107 (28%), Positives = 50/107 (46%), Gaps = 19/107 (17%) Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGT----VHEKLKWAFNLYDINKDGCITKEEMLA 189 + N DADGNG I F +F LS++ R E+L AF ++D + +G I+ E+ Sbjct: 51 MINEVDADGNGTIDFPEF---LSLMARKMKEQDSEEELIEAFKVFDRDGNGLISAAEL-- 105 Query: 190 IMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFL 236 RH L E + V+ ++ D + DG + +EF+ Sbjct: 106 ----------RHVMTNLGEKLTDDEVDEMIREADIDGDGHINYEEFV 142 Score = 29.6 bits (65), Expect = 1.4, Method: Compositional matrix adjust. Identities = 12/29 (41%), Positives = 20/29 (68%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSI 194 + K AF L+D + DG IT +E+ +M+S+ Sbjct: 11 EFKEAFALFDKDGDGTITTKELGTVMRSL 39 Score = 28.5 bits (62), Expect = 2.9, Method: Compositional matrix adjust. Identities = 26/105 (24%), Positives = 44/105 (41%), Gaps = 1/105 (0%) Query: 89 TKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHF 148 T+ ELQ + + G +D F + ++ + D+ F FD DGNG I Sbjct: 44 TEAELQDMINEVDADG-NGTIDFPEFLSLMARKMKEQDSEEELIEAFKVFDRDGNGLISA 102 Query: 149 EDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS 193 + ++ L +++ DI+ DG I EE + +M S Sbjct: 103 AELRHVMTNLGEKLTDDEVDEMIREADIDGDGHINYEEFVRMMVS 147 >1GGZ-A nrPDB Length = 148 Score = 40.8 bits (94), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 26/104 (25%), Positives = 51/104 (49%), Gaps = 13/104 (12%) Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGTVH-EKLKWAFNLYDINKDGCITKEEMLAIMK 192 + + D DGNG + F +F+ ++ ++ T + E+++ AF ++D + +G ++ E+ Sbjct: 51 MMSEIDRDGNGTVDFPEFLGMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAAEL----- 105 Query: 193 SIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFL 236 RH L E E V+ + D + DG V +EF+ Sbjct: 106 -------RHVMTRLGEKLSDEEVDEMIRAADTDGDGQVNYEEFV 142 Score = 37.0 bits (84), Expect = 0.009, Method: Compositional matrix adjust. Identities = 24/72 (33%), Positives = 39/72 (54%), Gaps = 14/72 (19%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRH-TYPILREDAPLEHVERFFQKMDR 224 + K AF+L+D + DGCIT E+ +M+S+ G++ T LR+ ++DR Sbjct: 11 EFKEAFSLFDKDGDGCITTRELGTVMRSL----GQNPTEAELRD---------MMSEIDR 57 Query: 225 NQDGVVTIDEFL 236 + +G V EFL Sbjct: 58 DGNGTVDFPEFL 69 >3O4Y-A nrPDB Length = 196 Score = 40.8 bits (94), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 29/109 (26%), Positives = 56/109 (51%), Gaps = 10/109 (9%) Query: 133 FLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKW-AFNLYDINKDGCITKEEMLAIM 191 L + D+DG+G I + +F+ + + R + +KL + AF ++D++ DG IT E+ ++ Sbjct: 94 LLLDQIDSDGSGNIDYTEFLA--AAIDRRQLSKKLIYCAFRVFDVDNDGEITTAELAHVL 151 Query: 192 KSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQ 240 G I D + V++ +++D+N DG + EF E + Sbjct: 152 -----FNGNKRGNITERD--VNQVKKMIREVDKNGDGKIDFYEFSEMMK 193 >2JNX-A nrPDB Length = 134 Score = 40.8 bits (94), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 34/108 (31%), Positives = 47/108 (43%), Gaps = 19/108 (17%) Query: 132 HFLFNAFDADGNGAIHFEDFV-VGLSILLRGTVHEK--LKWAFNLYDINKDGCITKEEML 188 +F A D DGNG I +F ++ + EK LK + L D + DG +TKEE+ Sbjct: 39 QLIFKAIDIDGNGEIDLAEFTKFAAAVKEQDLSDEKVGLKILYKLMDADGDGKLTKEEVT 98 Query: 189 AIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFL 236 K + Y E V K D N DG +T++EFL Sbjct: 99 TFFK-------KFGY---------EKVVDQIMKADANGDGYITLEEFL 130 >4I2Y-A nrPDB Length = 421 Score = 40.4 bits (93), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 28/105 (26%), Positives = 49/105 (46%), Gaps = 13/105 (12%) Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKDGCITKEEMLAIMK 192 + N DADG+G F +F+ ++ + T E+++ AF ++D + +G I E+ Sbjct: 324 MINEVDADGDGTFDFPEFLTMMARKMNDTDSEEEIREAFRVFDKDGNGYIGAAEL----- 378 Query: 193 SIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLE 237 RH L E E V+ + D + DG V +EF++ Sbjct: 379 -------RHVMTDLGEKLTDEEVDEMIRVADIDGDGQVNYEEFVQ 416 Score = 31.6 bits (70), Expect = 0.32, Method: Compositional matrix adjust. Identities = 21/83 (25%), Positives = 38/83 (45%), Gaps = 12/83 (14%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRN 225 + K AF+L+D + DG IT +E+ +M+S L ++ ++ ++D + Sbjct: 284 EFKEAFSLFDKDGDGTITTKELGTVMRS------------LGQNPTEAELQDMINEVDAD 331 Query: 226 QDGVVTIDEFLETCQKDENIMNS 248 DG EFL + N +S Sbjct: 332 GDGTFDFPEFLTMMARKMNDTDS 354 Score = 30.4 bits (67), Expect = 0.84, Method: Compositional matrix adjust. Identities = 17/59 (28%), Positives = 28/59 (47%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS 193 F FD DGNG I + ++ L E++ + DI+ DG + EE + +M + Sbjct: 362 FRVFDKDGNGYIGAAELRHVMTDLGEKLTDEEVDEMIRVADIDGDGQVNYEEFVQMMTA 420 >3Q5I-A nrPDB Length = 504 Score = 40.0 bits (92), Expect = 9e-04, Method: Compositional matrix adjust. Identities = 32/106 (30%), Positives = 52/106 (49%), Gaps = 20/106 (18%) Query: 139 DADGNGAIHFEDFVVGLSILLRGTV---HEKLKWAFNLYDINKDGCITKEEMLAIMKSIY 195 D D NG I + +F+ S+ + + E+L+ AFNL+D +K G ITKEE LA + + Sbjct: 409 DFDKNGYIEYSEFI---SVCMDKQILFSEERLRRAFNLFDTDKSGKITKEE-LANLFGLT 464 Query: 196 DMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 + + +L E D+N+D ++ DEF+ K Sbjct: 465 SISEKTWNDVLGE-------------ADQNKDNMIDFDEFVSMMHK 497 >2HF5-A nrPDB Length = 68 Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust. Identities = 19/62 (30%), Positives = 38/62 (61%), Gaps = 1/62 (1%) Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKDGCITKEEMLAIMK 192 + N DADGNG I F +F+ ++ ++ T E+++ AF ++D + +G I+ E+ +M Sbjct: 6 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT 65 Query: 193 SI 194 ++ Sbjct: 66 NL 67 >2LM5-A nrPDB Length = 214 Score = 39.7 bits (91), Expect = 0.001, Method: Compositional matrix adjust. Identities = 43/200 (21%), Positives = 84/200 (42%), Gaps = 14/200 (7%) Query: 61 DSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECP-------TGLVDEDT 113 D D + S R E L + Q T TK+E+ +R F P + L + Sbjct: 18 DDDDKHMGGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVP 77 Query: 114 FKLIYSQFFPQGDATTYAHFLFNAFD-ADGNGAIHFEDFVVGLSILL-RGTVHEKLKWAF 171 F+ I S P+ A + + F + ++ FEDF+ LS+ T K +AF Sbjct: 78 FEQILS--LPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAF 135 Query: 172 NLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVT 231 ++D + DG + +E++ ++ + G L + ++ ++ D ++DG + Sbjct: 136 RIFDFDDDGTLNREDLSRLVNC---LTGEGEDTRLSASEMKQLIDNILEESDIDRDGTIN 192 Query: 232 IDEFLETCQKDENIMNSMQL 251 + EF + + +S ++ Sbjct: 193 LSEFQHVISRSPDFASSFKI 212 >5E37-A nrPDB Length = 356 Score = 39.7 bits (91), Expect = 0.001, Method: Compositional matrix adjust. Identities = 24/75 (32%), Positives = 44/75 (58%), Gaps = 11/75 (14%) Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIYD----MMGRHTYPILREDAPLEHVERFFQ 220 E+L+ F + D++ +G I +EE+ +++S+ MM +H P ED +ER + Sbjct: 29 EELERRFKMADVDGNGHIDREELRNLLESMESGEVYMMSQHWLP---ED----ELERCME 81 Query: 221 KMDRNQDGVVTIDEF 235 + D N+DGV++ +EF Sbjct: 82 QYDVNKDGVISFEEF 96 Score = 37.0 bits (84), Expect = 0.008, Method: Compositional matrix adjust. Identities = 32/110 (29%), Positives = 47/110 (42%), Gaps = 20/110 (18%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVH---------EKLKWAFNLYDINKDGCITKE 185 F D DGNG I E+ L + G V+ ++L+ YD+NKDG I+ E Sbjct: 35 FKMADVDGNGHIDREELRNLLESMESGEVYMMSQHWLPEDELERCMEQYDVNKDGVISFE 94 Query: 186 EMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEF 235 E I IYD L + L E F+ +D++ +G + E Sbjct: 95 EFKQI---IYDG--------LLLEGTLAEYESAFKAVDKSGNGTIGATEL 133 >5UKG-A nrPDB Length = 419 Score = 39.7 bits (91), Expect = 0.001, Method: Compositional matrix adjust. Identities = 28/105 (26%), Positives = 49/105 (46%), Gaps = 13/105 (12%) Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGTV-HEKLKWAFNLYDINKDGCITKEEMLAIMK 192 + N DADG+G F +F+ ++ + V E+++ AF ++D + +G I E+ Sbjct: 322 MINEVDADGDGTFDFPEFLTMMARKMSYRVTEEEIREAFRVFDKDGNGYIGAAEL----- 376 Query: 193 SIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLE 237 RH L E E V+ + D + DG V +EF++ Sbjct: 377 -------RHVMTDLGEKLTDEEVDEMIRVADIDGDGQVNYEEFVQ 414 Score = 31.2 bits (69), Expect = 0.48, Method: Compositional matrix adjust. Identities = 19/71 (26%), Positives = 34/71 (47%), Gaps = 12/71 (16%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRN 225 + K AF+L+D + DG IT +E+ +M+S L ++ ++ ++D + Sbjct: 282 EFKEAFSLFDKDGDGTITTKELGTVMRS------------LGQNPTEAELQDMINEVDAD 329 Query: 226 QDGVVTIDEFL 236 DG EFL Sbjct: 330 GDGTFDFPEFL 340 >2BL0-C nrPDB Length = 142 Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust. Identities = 25/99 (25%), Positives = 47/99 (47%), Gaps = 2/99 (2%) Query: 106 TGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHE 165 TG + ++ + + QF + + + +FN DA GNG I F +F+ + ++ T E Sbjct: 20 TGFITKEGLQTVLKQFGVRVEPAAFNE-MFNEADATGNGKIQFPEFLSMMGRRMKQTTSE 78 Query: 166 K-LKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTY 203 L+ AF +D G I K + + ++ D + H + Sbjct: 79 DILRQAFRTFDPEGTGYIPKAALQDALLNLGDRLKPHEF 117 >2M29-A nrPDB Length = 171 Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust. Identities = 34/101 (33%), Positives = 48/101 (47%), Gaps = 20/101 (19%) Query: 143 NGAIHFEDFVVGLSILLRG-TVH----EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDM 197 G + FE+FV +S LR T H +L+ AF +D ++DG IT E+ Sbjct: 78 GGFVDFEEFVELISPKLREETAHMLGVRELRIAFREFDKDRDGRITVAEL---------- 127 Query: 198 MGRHTYPILREDAPLEHVE--RFFQKMDRNQDGVVTIDEFL 236 R P L + PLE E ++MD N DG + DEF+ Sbjct: 128 --RQAAPALLGE-PLEGTELDEMLREMDLNGDGTIDFDEFV 165 >1JC2-A nrPDB Length = 76 Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust. Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 12/77 (15%) Query: 160 RGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFF 219 +G E+L F ++D N DG I EE+ I+++ G H E +E Sbjct: 5 KGKSEEELANCFRIFDKNADGFIDIEELGEILRAT----GEHVIE--------EDIEDLM 52 Query: 220 QKMDRNQDGVVTIDEFL 236 + D+N DG + DEFL Sbjct: 53 KDSDKNNDGRIDFDEFL 69 >2KSZ-A nrPDB Length = 76 Score = 38.9 bits (89), Expect = 0.002, Method: Compositional matrix adjust. Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 12/75 (16%) Query: 167 LKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQ 226 K AF L+D + DGCIT EE+ +++S L ++ E ++ ++D + Sbjct: 12 FKEAFGLFDKDGDGCITVEELATVIRS------------LDQNPTEEELQDMISEVDADG 59 Query: 227 DGVVTIDEFLETCQK 241 +G + DEFL K Sbjct: 60 NGTIEFDEFLSLMAK 74 Score = 31.2 bits (69), Expect = 0.42, Method: Compositional matrix adjust. Identities = 17/57 (29%), Positives = 29/57 (50%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIM 191 F FD DG+G I E+ + L + E+L+ + D + +G I +E L++M Sbjct: 16 FGLFDKDGDGCITVEELATVIRSLDQNPTEEELQDMISEVDADGNGTIEFDEFLSLM 72 >4WPX-A nrPDB Length = 177 Score = 38.5 bits (88), Expect = 0.003, Method: Compositional matrix adjust. Identities = 26/113 (23%), Positives = 50/113 (44%), Gaps = 37/113 (32%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSI---------YDMMGRH-----TYP------- 204 ++ AF L+D NKDG ++ EE +++++ YDM+ RH +P Sbjct: 27 RISEAFELFDSNKDGLLSYEEFRFVLRALGFDLPKQQTYDMLVRHGQRPANWPHDQECPP 86 Query: 205 ----------------ILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 ++R+ P + + R F+ D + G++T D+ + CQ+ Sbjct: 87 VYRQFNLATAQALAGTLIRQRDPRDELRRAFRLFDVDGKGMITEDDLRKVCQQ 139 >3KHE-A nrPDB Length = 191 Score = 38.5 bits (88), Expect = 0.003, Method: Compositional matrix adjust. Identities = 34/111 (30%), Positives = 51/111 (45%), Gaps = 20/111 (18%) Query: 134 LFNAFDADGNGAIHFEDFV---VGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAI 190 + + D D NG I + +FV + +LL E+L AF +D + G IT EE+ Sbjct: 92 ILQSVDFDRNGYIEYSEFVTVCMDKQLLLS---RERLLAAFQQFDSDGSGKITNEEL--- 145 Query: 191 MKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 GR + + D H + Q+ D+N DG V +EF+E QK Sbjct: 146 --------GR-LFGVTEVDDETWH--QVLQECDKNNDGEVDFEEFVEMMQK 185 >1DGU-A nrPDB Length = 183 Score = 38.1 bits (87), Expect = 0.003, Method: Compositional matrix adjust. Identities = 39/184 (21%), Positives = 79/184 (42%), Gaps = 14/184 (7%) Query: 77 EGLDQLQAQTKFTKKELQSLYRGFKNECP-------TGLVDEDTFKLIYSQFFPQGDATT 129 E L + Q T TK+E+ +R F P + L + F+ I S P+ A Sbjct: 3 ELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILS--LPELKANP 60 Query: 130 YAHFLFNAFD-ADGNGAIHFEDFVVGLSILL-RGTVHEKLKWAFNLYDINKDGCITKEEM 187 + + F + ++ FEDF+ LS+ T K +AF ++D + DG + +E++ Sbjct: 61 FKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDL 120 Query: 188 LAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMN 247 ++ + G L + ++ ++ D ++DG + + EF + + + Sbjct: 121 SRLVNC---LTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDFAS 177 Query: 248 SMQL 251 S ++ Sbjct: 178 SFKI 181 >3HZT-A nrPDB Length = 467 Score = 38.1 bits (87), Expect = 0.004, Method: Compositional matrix adjust. Identities = 34/111 (30%), Positives = 51/111 (45%), Gaps = 20/111 (18%) Query: 134 LFNAFDADGNGAIHFEDFV---VGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAI 190 + + D D NG I + +FV + +LL E+L AF +D + G IT EE+ Sbjct: 366 ILQSVDFDRNGYIEYSEFVTVCMDKQLLLS---RERLLAAFQQFDSDGSGKITNEEL--- 419 Query: 191 MKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 GR + + D H + Q+ D+N DG V +EF+E QK Sbjct: 420 --------GR-LFGVTEVDDETWH--QVLQECDKNNDGEVDFEEFVEMMQK 459 >5JN2-A nrPDB Length = 525 Score = 38.1 bits (87), Expect = 0.004, Method: Compositional matrix adjust. Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 21/115 (18%) Query: 126 DATTYAHFL---FNAFDADGNGAIHFEDFVVGLSILLRGTV--HEKLKWAFNLYDINKDG 180 DA+ H + +A D D NG I + +FV + R T+ E+L+ AF ++D + G Sbjct: 417 DASAVEHEVDQVLDAVDFDKNGYIEYSEFVT--VAMDRKTLLSRERLERAFRMFDSDNSG 474 Query: 181 CITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEF 235 I+ E+ I D E + ++D+N DG V DEF Sbjct: 475 KISSTELATIFGV--------------SDVDSETWKSVLSEVDKNNDGEVDFDEF 515 >3AAJ-A nrPDB Length = 167 Score = 37.7 bits (86), Expect = 0.005, Method: Compositional matrix adjust. Identities = 28/105 (26%), Positives = 54/105 (51%), Gaps = 12/105 (11%) Query: 92 ELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDF 151 + Q+++R + + +G++D++ K S + + + L FD G G I F+DF Sbjct: 72 DWQNVFRTYDRD-NSGMIDKNELKQALSGYRL---SDQFHDILIRKFDRQGRGQIAFDDF 127 Query: 152 VVGLSILLRGTVHEKLKWAFNLYDINKDGCI--TKEEMLAIMKSI 194 + G +L ++L F YD ++DG I + E+ L+++ SI Sbjct: 128 IQGCIVL------QRLTDIFRRYDTDQDGWIQVSYEQYLSMVFSI 166 >1OZS-A nrPDB Length = 73 Score = 37.4 bits (85), Expect = 0.006, Method: Compositional matrix adjust. Identities = 24/79 (30%), Positives = 39/79 (49%), Gaps = 12/79 (15%) Query: 159 LRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERF 218 ++G E+L F ++D N DG I EE+ ++++ T + ED +E Sbjct: 1 MKGKSEEELSDLFRMFDKNADGYIDLEELKIMLQA--------TGETITED----DIEEL 48 Query: 219 FQKMDRNQDGVVTIDEFLE 237 + D+N DG + DEFLE Sbjct: 49 MKDGDKNNDGRIDYDEFLE 67 >2MA2-A nrPDB Length = 81 Score = 37.4 bits (85), Expect = 0.006, Method: Composition-based stats. Identities = 22/56 (39%), Positives = 32/56 (57%), Gaps = 7/56 (12%) Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLA 189 +F FD DG+G I E+F + +RG AF D N+DGCI++EEM++ Sbjct: 18 VFRNFDVDGDGHISQEEFQI-----IRGNF--PYLSAFGDLDQNQDGCISREEMVS 66 Score = 27.3 bits (59), Expect = 6.2, Method: Composition-based stats. Identities = 18/84 (21%), Positives = 38/84 (45%), Gaps = 19/84 (22%) Query: 163 VHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKM 222 + + ++ F +D++ DG I++EE I R +P L F + Sbjct: 11 IEKMVESVFRNFDVDGDGHISQEEFQII---------RGNFPYLSA----------FGDL 51 Query: 223 DRNQDGVVTIDEFLETCQKDENIM 246 D+NQDG ++ +E + + +++ Sbjct: 52 DQNQDGCISREEMVSYFLRSSSVL 75 >4YZB-A nrPDB Length = 491 Score = 37.0 bits (84), Expect = 0.008, Method: Compositional matrix adjust. Identities = 29/104 (27%), Positives = 49/104 (47%), Gaps = 18/104 (17%) Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGTV--HEKLKWAFNLYDINKDGCITKEEMLAIM 191 + +A D D NG I + +FV + R T+ ++L+ AF ++D + G I+ E+ I Sbjct: 391 VLDAVDFDKNGFIEYSEFVT--VAMDRKTLLSRQRLERAFGMFDADGSGKISSSELATI- 447 Query: 192 KSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEF 235 + + D+ E R ++DRN DG V +EF Sbjct: 448 -----------FGVSEVDS--ETWRRVLAEVDRNNDGEVDFEEF 478 >1S6I-A nrPDB Length = 188 Score = 37.0 bits (84), Expect = 0.009, Method: Compositional matrix adjust. Identities = 28/107 (26%), Positives = 47/107 (43%), Gaps = 12/107 (11%) Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS 193 LF D D +G I F++ GL + + ++K + DI+K G I E +A Sbjct: 15 LFKMIDTDNSGTITFDELKDGLKRVGSELMESEIKDLMDAADIDKSGTIDYGEFIAATV- 73 Query: 194 IYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQ 240 H + RE E++ F D++ G +T+DE + C+ Sbjct: 74 -------HLNKLERE----ENLVSAFSYFDKDGSGYITLDEIQQACK 109 Score = 30.8 bits (68), Expect = 0.54, Method: Compositional matrix adjust. Identities = 27/110 (24%), Positives = 48/110 (43%), Gaps = 18/110 (16%) Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS 193 L +A D D +G I + +F+ L + E L AF+ +D + G IT +E+ K Sbjct: 51 LMDAADIDKSGTIDYGEFIAATVHLNKLEREENLVSAFSYFDKDGSGYITLDEIQQACK- 109 Query: 194 IYDMMGRHTYPILREDAPLE--HVERFFQKMDRNQDGVVTIDEFLETCQK 241 D L+ H++ +++D++ DG + EF +K Sbjct: 110 ---------------DFGLDDIHIDDMIKEIDQDNDGQIDYGEFAAMMRK 144 >3FWC-A nrPDB Length = 161 Score = 36.2 bits (82), Expect = 0.014, Method: Compositional matrix adjust. Identities = 26/89 (29%), Positives = 40/89 (44%), Gaps = 27/89 (30%) Query: 170 AFNLYDINKDGCITKEEMLAIMKSI---------------YDMMGRHTY----------- 203 AF+L+D+N DG + E+ MK++ YD GRH Sbjct: 28 AFSLFDMNNDGFLDYHELKVAMKALGFELPKREILDLIDEYDSEGRHLMKYDDFYIVMGE 87 Query: 204 PILREDAPLEHVERFFQKMDRNQDGVVTI 232 IL+ D PL+ ++R FQ D + G ++I Sbjct: 88 KILKRD-PLDEIKRAFQLFDDDHTGKISI 115 >2NCO-A nrPDB Length = 102 Score = 36.2 bits (82), Expect = 0.015, Method: Compositional matrix adjust. Identities = 19/65 (29%), Positives = 33/65 (50%), Gaps = 5/65 (7%) Query: 171 FNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVV 230 F YD + G + +E+ ++K Y MG + +ED V+ + Q D N DG V Sbjct: 21 FKRYDKDGSGQLQDDEIAGLLKDTYAEMGMSNFTPTKED-----VKIWLQMADTNSDGSV 75 Query: 231 TIDEF 235 +++E+ Sbjct: 76 SLEEY 80 >2I18-A nrPDB Length = 64 Score = 35.8 bits (81), Expect = 0.020, Method: Composition-based stats. Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 16/71 (22%) Query: 167 LKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQ 226 LK + L D++ DG +TKEE+ + K +H +E V K D N Sbjct: 7 LKVLYKLMDVDGDGKLTKEEVTSFFK-------KHG---------IEKVAEQVMKADANG 50 Query: 227 DGVVTIDEFLE 237 DG +T++EFLE Sbjct: 51 DGYITLEEFLE 61 >3UL4-B nrPDB Length = 65 Score = 35.4 bits (80), Expect = 0.024, Method: Composition-based stats. Identities = 20/60 (33%), Positives = 34/60 (56%), Gaps = 3/60 (5%) Query: 139 DADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMM 198 D + NG ++ ED+++ + LLRG KL N+ D+NKDG + + L + K I ++ Sbjct: 7 DLNRNGIVNDEDYILLKNYLLRGN---KLVIDLNVADVNKDGKVNSTDCLFLKKYILGLI 63 >1YX7-A nrPDB Length = 83 Score = 35.4 bits (80), Expect = 0.027, Method: Composition-based stats. Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 6/74 (8%) Query: 163 VHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKM 222 V +L+ AF D N DG +T E+ M ++ Y L +D E + + Sbjct: 5 VKAELEAAFKKLDANGDGYVTALELQTFMVTL------DAYKALSKDKVKEASAKLIKMA 58 Query: 223 DRNQDGVVTIDEFL 236 D+N DG ++ +EFL Sbjct: 59 DKNSDGKISKEEFL 72 Score = 29.3 bits (64), Expect = 1.7, Method: Composition-based stats. Identities = 21/60 (35%), Positives = 29/60 (48%), Gaps = 6/60 (10%) Query: 135 FNAFDADGNG---AIHFEDFVVGL---SILLRGTVHEKLKWAFNLYDINKDGCITKEEML 188 F DA+G+G A+ + F+V L L + V E + D N DG I+KEE L Sbjct: 13 FKKLDANGDGYVTALELQTFMVTLDAYKALSKDKVKEASAKLIKMADKNSDGKISKEEFL 72 >4N5X-A nrPDB Length = 199 Score = 35.0 bits (79), Expect = 0.028, Method: Compositional matrix adjust. Identities = 30/115 (26%), Positives = 47/115 (40%), Gaps = 23/115 (20%) Query: 129 TYAHFLFNAFDADGNGAIHFEDFVVGL---SILLRGTVHEKLKWAFNLYDINKDGCITKE 185 T LF A D +G+G + + GL I L EK+ F D+NKDG + E Sbjct: 22 TRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEEKI---FTTGDVNKDGKLDFE 78 Query: 186 EMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQ 240 E + +K M + F+ +D+N DG + E +++ Q Sbjct: 79 EFMKYLKDHEKKM-----------------KLAFKSLDKNNDGKIEASEIVQSLQ 116 Score = 28.5 bits (62), Expect = 2.6, Method: Compositional matrix adjust. Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 7/62 (11%) Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGTVHEK-LKWAFNLYDINKDGCITKEEMLAIMK 192 +F D + +G + FE+F+ L HEK +K AF D N DG I E++ ++ Sbjct: 63 IFTTGDVNKDGKLDFEEFMKYLK------DHEKKMKLAFKSLDKNNDGKIEASEIVQSLQ 116 Query: 193 SI 194 ++ Sbjct: 117 TL 118 >5D43-A nrPDB Length = 178 Score = 35.0 bits (79), Expect = 0.036, Method: Compositional matrix adjust. Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 1/103 (0%) Query: 90 KKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFE 149 K+E++ + E TG + + F + +Q + D F FD D G I F+ Sbjct: 66 KEEMKKMISEVDKEA-TGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFK 124 Query: 150 DFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMK 192 + + L E+L+ + D + DG + +EE L IMK Sbjct: 125 NLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 Score = 34.3 bits (77), Expect = 0.057, Method: Compositional matrix adjust. Identities = 29/110 (26%), Positives = 52/110 (47%), Gaps = 15/110 (13%) Query: 134 LFNAFDADGNGAIHFEDFVVGLS--ILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIM 191 + + D + G I F DF+ ++ + + T E LK AF L+D ++ G I+ + Sbjct: 72 MISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILK-AFRLFDDDETGKIS----FKNL 126 Query: 192 KSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 K + + +G E E ++ + DR+ DG V +EFL+ +K Sbjct: 127 KRVANELG--------ESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKK 168 >2KGR-A nrPDB Length = 111 Score = 34.7 bits (78), Expect = 0.039, Method: Compositional matrix adjust. Identities = 29/102 (28%), Positives = 51/102 (50%), Gaps = 10/102 (9%) Query: 123 PQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHE-KLKWAFNLYDINKDGC 181 PQ Y LFN+ D +G + +IL++ ++ + +L +NL DI++DG Sbjct: 9 PQSSRLKYRQ-LFNSHDKTMSGHLTGPQ---ARTILMQSSLPQAQLASIWNLSDIDQDGK 64 Query: 182 ITKEEMLAIMKSI-YDMMGRHTYPILREDAPLEHVERFFQKM 222 +T EE + M I M G+ P+L P E++ F+++ Sbjct: 65 LTAEEFILAMHLIDVAMSGQPLPPVL----PPEYIPPSFRRV 102 >2RO8-A nrPDB Length = 79 Score = 34.7 bits (78), Expect = 0.040, Method: Compositional matrix adjust. Identities = 21/72 (29%), Positives = 39/72 (54%), Gaps = 14/72 (19%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLE-HVERFFQKMDR 224 + K AF+L+D + DGCIT +E+ +M+S +G++ P E ++ ++D Sbjct: 11 EFKEAFSLFDKDGDGCITTKELGTVMRS----LGQN---------PTEAELQDMINEVDA 57 Query: 225 NQDGVVTIDEFL 236 + +G + EFL Sbjct: 58 DGNGTIDFPEFL 69 >4ZCV-A nrPDB Length = 165 Score = 34.7 bits (78), Expect = 0.044, Method: Compositional matrix adjust. Identities = 29/110 (26%), Positives = 46/110 (41%), Gaps = 23/110 (20%) Query: 134 LFNAFDADGNGAIHFEDFVVGL---SILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAI 190 LF A D +G+G + + GL I L EK+ F D+NKDG + EE + Sbjct: 18 LFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEEKI---FTTGDVNKDGKLDFEEFMKY 74 Query: 191 MKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQ 240 +K M + F+ +D+N DG + E +++ Q Sbjct: 75 LKDHEKKM-----------------KLAFKSLDKNNDGKIEASEIVQSLQ 107 Score = 28.5 bits (62), Expect = 3.2, Method: Compositional matrix adjust. Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 7/62 (11%) Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGTVHEK-LKWAFNLYDINKDGCITKEEMLAIMK 192 +F D + +G + FE+F+ L HEK +K AF D N DG I E++ ++ Sbjct: 54 IFTTGDVNKDGKLDFEEFMKYLK------DHEKKMKLAFKSLDKNNDGKIEASEIVQSLQ 107 Query: 193 SI 194 ++ Sbjct: 108 TL 109 Score = 28.1 bits (61), Expect = 3.4, Method: Compositional matrix adjust. Identities = 13/22 (59%), Positives = 14/22 (63%) Query: 216 ERFFQKMDRNQDGVVTIDEFLE 237 E FQ +DRN DGVV I E E Sbjct: 16 ETLFQALDRNGDGVVDIGELQE 37 >2LMV-A nrPDB Length = 148 Score = 34.7 bits (78), Expect = 0.046, Method: Compositional matrix adjust. Identities = 23/97 (23%), Positives = 49/97 (50%), Gaps = 13/97 (13%) Query: 141 DGNGAIHFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMG 199 + NG ++F +F ++ +R T E+++ AF ++D + DG I+ E+ +M + Sbjct: 58 NNNGQLNFTEFCGIMAKQMRETDTEEEMREAFKIFDRDGDGFISPAELRFVMIN------ 111 Query: 200 RHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFL 236 L E E ++ ++ D + DG++ +EF+ Sbjct: 112 ------LGEKVTDEEIDEMIREADFDGDGMINYEEFV 142 >4RGJ-A nrPDB Length = 520 Score = 33.9 bits (76), Expect = 0.065, Method: Compositional matrix adjust. Identities = 32/105 (30%), Positives = 51/105 (48%), Gaps = 20/105 (19%) Query: 134 LFNAFDADGNGAIHFEDFVVGLSI---LLRGTVHEKLKWAFNLYDINKDGCITKEEMLAI 190 + N+ D D NG I + +F+ +SI LL T E+L+ AF L+D + G I+ E LA Sbjct: 423 ILNSIDLDQNGYIEYSEFLT-VSIDRKLLLST--ERLEKAFKLFDKDGSGKISANE-LAQ 478 Query: 191 MKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEF 235 + + D+ +L+E +D+N DG + EF Sbjct: 479 LFGLSDVSSECWKTVLKE-------------VDQNNDGEIDFKEF 510 >2AAO-A nrPDB Length = 166 Score = 33.9 bits (76), Expect = 0.078, Method: Compositional matrix adjust. Identities = 41/174 (23%), Positives = 67/174 (38%), Gaps = 27/174 (15%) Query: 81 QLQAQTKFTKKELQSLYRGFKNECPTGL------VDEDTFKLIYSQFFPQGDATTYAHF- 133 Q A KF K L+ + E GL +D D I + G A+ Sbjct: 2 QFSAMNKFKKMALRVIAESLSEEEIAGLKEMFNMIDADKSGQITFEELKAGLKRVGANLK 61 Query: 134 ------LFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEM 187 L A D D +G I +++F+ L + + L AF +D + G IT +E+ Sbjct: 62 ESEILDLMQAADVDNSGTIDYKEFIAATLHLNKIEREDHLFAAFTYFDKDGSGYITPDEL 121 Query: 188 LAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 + + ED +E + R +D++ DG + +EF+ QK Sbjct: 122 ---------QQACEEFGV--EDVRIEELMR---DVDQDNDGRIDYNEFVAMMQK 161 >2GGM-A nrPDB Length = 172 Score = 33.5 bits (75), Expect = 0.082, Method: Compositional matrix adjust. Identities = 35/134 (26%), Positives = 57/134 (42%), Gaps = 29/134 (21%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGC------------- 181 F+ FDADG G I ++ V + L E++K + +I+K+G Sbjct: 37 FDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKM--ISEIDKEGTGKMNFGDFLTVMT 94 Query: 182 ------ITKEEMLAIMKSI-YDMMGRHTYPILR-------EDAPLEHVERFFQKMDRNQD 227 TKEE+L K D G+ ++ L+ E+ E ++ + DR+ D Sbjct: 95 QKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGD 154 Query: 228 GVVTIDEFLETCQK 241 G V+ EFL +K Sbjct: 155 GEVSEQEFLRIMKK 168 >1C7W-A nrPDB Length = 81 Score = 33.5 bits (75), Expect = 0.082, Method: Compositional matrix adjust. Identities = 25/88 (28%), Positives = 44/88 (50%), Gaps = 11/88 (12%) Query: 159 LRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERF 218 +R E++ AF ++D N DG I +E IM+ + P+ DA VE Sbjct: 2 VRQDDEEEILRAFKVFDANGDGVIDFDEFKFIMQKV------GEEPLT--DA---EVEEA 50 Query: 219 FQKMDRNQDGVVTIDEFLETCQKDENIM 246 ++ D + +GV+ I EF++ +K +N + Sbjct: 51 MKEADEDGNGVIDIPEFMDLIKKSKNAL 78 Score = 29.3 bits (64), Expect = 1.9, Method: Compositional matrix adjust. Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 9/63 (14%) Query: 135 FNAFDADGNGAIHFEDF-----VVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLA 189 F FDA+G+G I F++F VG L V E +K A D + +G I E + Sbjct: 14 FKVFDANGDGVIDFDEFKFIMQKVGEEPLTDAEVEEAMKEA----DEDGNGVIDIPEFMD 69 Query: 190 IMK 192 ++K Sbjct: 70 LIK 72 >2ROB-A nrPDB Length = 70 Score = 33.5 bits (75), Expect = 0.091, Method: Compositional matrix adjust. Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 12/73 (16%) Query: 164 HEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMD 223 E+LK AF ++D +++G I+ E+ RH L E E VE+ ++ D Sbjct: 3 EEELKEAFKVFDKDQNGYISASEL------------RHVMINLGEKLTDEEVEQMIKEAD 50 Query: 224 RNQDGVVTIDEFL 236 + DG V +EF+ Sbjct: 51 LDGDGQVNYEEFV 63 >2KN2-A nrPDB Length = 92 Score = 33.1 bits (74), Expect = 0.11, Method: Compositional matrix adjust. Identities = 22/72 (30%), Positives = 36/72 (50%), Gaps = 12/72 (16%) Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDR 224 E+LK AF ++D +++G I+ E+ RH L E E VE+ ++ D Sbjct: 9 EELKEAFKVFDKDQNGYISASEL------------RHVMINLGEKLTDEEVEQMIKEADL 56 Query: 225 NQDGVVTIDEFL 236 + DG V +EF+ Sbjct: 57 DGDGQVNYEEFV 68 >4MVF-A nrPDB Length = 506 Score = 32.7 bits (73), Expect = 0.15, Method: Compositional matrix adjust. Identities = 27/107 (25%), Positives = 46/107 (42%), Gaps = 14/107 (13%) Query: 132 HFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIM 191 H + D++ +G IH+ DF+ E F +DI+ +G I+ EE+ I Sbjct: 399 HQVLRDIDSNASGQIHYTDFLAATIDKQTYLKKEVCLIPFKFFDIDGNGKISVEELKRI- 457 Query: 192 KSIYDMMGRHTYPILREDAPL--EHVERFFQKMDRNQDGVVTIDEFL 236 GR + PL + ++ Q++D N DG + EF+ Sbjct: 458 ------FGRDDI-----ENPLIDKAIDSLLQEVDLNGDGEIDFHEFM 493 >3E3R-A nrPDB Length = 204 Score = 32.7 bits (73), Expect = 0.15, Method: Compositional matrix adjust. Identities = 27/102 (26%), Positives = 44/102 (43%), Gaps = 12/102 (11%) Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS 193 F D DG+ ++ ++F GL+ L + + +D N G + EE L Sbjct: 42 FFRQLDRDGSRSLDADEFRQGLAKLGLVLDQAEAEGVCRKWDRNGSGTLDLEEFL----- 96 Query: 194 IYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEF 235 R P + + A + F K+DR+ DGVVT+D+ Sbjct: 97 ------RALRPPMSQ-AREAVIAAAFAKLDRSGDGVVTVDDL 131 >2OBH-A nrPDB Length = 143 Score = 32.7 bits (73), Expect = 0.16, Method: Compositional matrix adjust. Identities = 35/134 (26%), Positives = 57/134 (42%), Gaps = 29/134 (21%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGC------------- 181 F+ FDADG G I ++ V + L E++K + +I+K+G Sbjct: 12 FDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKM--ISEIDKEGTGKMNFGDFLTVMT 69 Query: 182 ------ITKEEMLAIMKSI-YDMMGRHTYPILR-------EDAPLEHVERFFQKMDRNQD 227 TKEE+L K D G+ ++ L+ E+ E ++ + DR+ D Sbjct: 70 QKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGD 129 Query: 228 GVVTIDEFLETCQK 241 G V+ EFL +K Sbjct: 130 GEVSEQEFLRIMKK 143 >3L19-A nrPDB Length = 214 Score = 32.0 bits (71), Expect = 0.23, Method: Compositional matrix adjust. Identities = 31/125 (24%), Positives = 51/125 (40%), Gaps = 26/125 (20%) Query: 122 FPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGC 181 PQ ++ A + A D D NG I + +FV +KL+ AF +D + +G Sbjct: 102 LPQIESEVDA--ILGAADFDRNGYIDYSEFVTVAMDRKSLLSKDKLESAFQKFDQDGNGK 159 Query: 182 ITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVE-----RFFQKMDRNQDGVVTIDEFL 236 I+ +E+ ++ L+H+E +D N DG V +EF Sbjct: 160 ISVDELASVF-------------------GLDHLESKTWKEMISGIDSNNDGDVDFEEFC 200 Query: 237 ETCQK 241 + QK Sbjct: 201 KMIQK 205 >2SAS-A nrPDB Length = 185 Score = 32.0 bits (71), Expect = 0.23, Method: Compositional matrix adjust. Identities = 21/67 (31%), Positives = 34/67 (50%), Gaps = 5/67 (7%) Query: 175 DINKDGCITKEEMLAIM-KSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTID 233 DINKD ++ EE LA+ K+I P ++ + F+ MD + DG+V ++ Sbjct: 70 DINKDDVVSWEEYLAMWEKTIATCKSVADLPAWCQN----RIPFLFKGMDVSGDGIVDLE 125 Query: 234 EFLETCQ 240 EF C+ Sbjct: 126 EFQNYCK 132 >3KF9-A nrPDB Length = 149 Score = 32.0 bits (71), Expect = 0.24, Method: Compositional matrix adjust. Identities = 36/134 (26%), Positives = 57/134 (42%), Gaps = 29/134 (21%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGC--ITKEEML---- 188 F+ FD DG+G I ++ V + L E++K + DI+KDG I EE L Sbjct: 14 FDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKM--IADIDKDGSGTIDFEEFLQMMT 71 Query: 189 ----------AIMKSIY----DMMGRHTYPILR-------EDAPLEHVERFFQKMDRNQD 227 IMK+ D G+ ++ L+ E+ E ++ + DR+ D Sbjct: 72 AKMGERDSREEIMKAFRLFDDDETGKISFKNLKRVAKELGENMTDEELQEMIDEADRDGD 131 Query: 228 GVVTIDEFLETCQK 241 G V +EF +K Sbjct: 132 GEVNEEEFFRIMKK 145 Score = 29.6 bits (65), Expect = 1.4, Method: Compositional matrix adjust. Identities = 22/87 (25%), Positives = 37/87 (42%) Query: 106 TGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHE 165 +G +D + F + + + D+ F FD D G I F++ L E Sbjct: 58 SGTIDFEEFLQMMTAKMGERDSREEIMKAFRLFDDDETGKISFKNLKRVAKELGENMTDE 117 Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMK 192 +L+ + D + DG + +EE IMK Sbjct: 118 ELQEMIDEADRDGDGEVNEEEFFRIMK 144 Score = 29.3 bits (64), Expect = 1.9, Method: Compositional matrix adjust. Identities = 21/98 (21%), Positives = 48/98 (48%), Gaps = 19/98 (19%) Query: 164 HEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMD 223 ++++ AF+L+D + G I +E+ M++ L + E +++ +D Sbjct: 7 KQEIREAFDLFDTDGSGTIDAKELKVAMRA------------LGFEPKKEEIKKMIADID 54 Query: 224 RNQDGVVTIDEFLETC-----QKD--ENIMNSMQLFEN 254 ++ G + +EFL+ ++D E IM + +LF++ Sbjct: 55 KDGSGTIDFEEFLQMMTAKMGERDSREEIMKAFRLFDD 92 >3PM8-A nrPDB Length = 197 Score = 32.0 bits (71), Expect = 0.25, Method: Compositional matrix adjust. Identities = 28/107 (26%), Positives = 48/107 (44%), Gaps = 14/107 (13%) Query: 132 HFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIM 191 H + D++ +G IH+ DF+ E F +DI+ +G I+ EE + Sbjct: 96 HQVLRDIDSNASGQIHYTDFLAATIDKQTYLKKEVCLIPFKFFDIDGNGKISVEE----L 151 Query: 192 KSIYDMMGRHTYPILREDAPL--EHVERFFQKMDRNQDGVVTIDEFL 236 K I+ GR + PL + ++ Q++D N DG + EF+ Sbjct: 152 KRIF---GRDDI-----ENPLIDKAIDSLLQEVDLNGDGEIDFHEFM 190 >2LV7-A nrPDB Length = 100 Score = 32.0 bits (71), Expect = 0.29, Method: Compositional matrix adjust. Identities = 21/73 (28%), Positives = 39/73 (53%), Gaps = 14/73 (19%) Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLE-HVERFFQKMD 223 E+++ AF ++D + +G I+K+E+ M+S+ M P E +E Q++D Sbjct: 36 EEIREAFKVFDRDGNGFISKQELGTAMRSLGYM-------------PNEVELEVIIQRLD 82 Query: 224 RNQDGVVTIDEFL 236 + DG V +EF+ Sbjct: 83 MDGDGQVDFEEFV 95 >2M97-A nrPDB Length = 69 Score = 31.6 bits (70), Expect = 0.31, Method: Compositional matrix adjust. Identities = 23/62 (37%), Positives = 32/62 (51%), Gaps = 4/62 (6%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGT--VHEKLKWAFNLYDINKDGCITKEEMLAIMK 192 F FD DGNG I E+F G I L G E + F D +K+G I +E L +M+ Sbjct: 9 FRIFDKDGNGFIDREEF--GDIIRLTGEQLTDEDVDEIFGDSDTDKNGRIDFDEFLKMME 66 Query: 193 SI 194 ++ Sbjct: 67 NV 68 Score = 27.3 bits (59), Expect = 6.4, Method: Compositional matrix adjust. Identities = 19/73 (26%), Positives = 33/73 (45%), Gaps = 12/73 (16%) Query: 164 HEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMD 223 E+L F ++D + +G I +EE I++ + E E V+ F D Sbjct: 2 EEELSECFRIFDKDGNGFIDREEFGDIIR------------LTGEQLTDEDVDEIFGDSD 49 Query: 224 RNQDGVVTIDEFL 236 +++G + DEFL Sbjct: 50 TDKNGRIDFDEFL 62 >3LIJ-A nrPDB Length = 494 Score = 31.6 bits (70), Expect = 0.32, Method: Compositional matrix adjust. Identities = 31/125 (24%), Positives = 51/125 (40%), Gaps = 26/125 (20%) Query: 122 FPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGC 181 PQ ++ A + A D D NG I + +FV +KL+ AF +D + +G Sbjct: 385 LPQIESEVDA--ILGAADFDRNGYIDYSEFVTVAMDRKSLLSKDKLESAFQKFDQDGNGK 442 Query: 182 ITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVE-----RFFQKMDRNQDGVVTIDEFL 236 I+ +E+ ++ L+H+E +D N DG V +EF Sbjct: 443 ISVDELASVF-------------------GLDHLESKTWKEMISGIDSNNDGDVDFEEFC 483 Query: 237 ETCQK 241 + QK Sbjct: 484 KMIQK 488 >2I08-A nrPDB Length = 78 Score = 31.6 bits (70), Expect = 0.33, Method: Compositional matrix adjust. Identities = 13/29 (44%), Positives = 21/29 (72%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSI 194 + K AF+LYD + DG IT +E+ +M+S+ Sbjct: 11 EFKEAFSLYDKDGDGTITTKELGTVMRSL 39 Score = 28.5 bits (62), Expect = 3.2, Method: Compositional matrix adjust. Identities = 10/27 (37%), Positives = 18/27 (66%) Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLR 160 + N DADGNG I F +F+ ++ +++ Sbjct: 51 MINEVDADGNGTIDFPEFLTMMARIMK 77 >2PMY-A nrPDB Length = 91 Score = 31.6 bits (70), Expect = 0.38, Method: Compositional matrix adjust. Identities = 18/70 (25%), Positives = 30/70 (42%), Gaps = 14/70 (20%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRN 225 +L+ F D N+ G + +EE A+ + P E FQ++D + Sbjct: 28 RLRSVFAACDANRSGRLEREEFRALCTEL------RVRPA--------DAEAVFQRLDAD 73 Query: 226 QDGVVTIDEF 235 +DG +T EF Sbjct: 74 RDGAITFQEF 83 >4MSP-A nrPDB Length = 200 Score = 31.2 bits (69), Expect = 0.41, Method: Compositional matrix adjust. Identities = 22/74 (29%), Positives = 38/74 (51%), Gaps = 6/74 (8%) Query: 170 AFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGV 229 +F D+N D ++K+E+ A +K ++ G ++ E VE F K D ++DG Sbjct: 132 SFQEMDLNDDWKLSKDEVKAYLKKEFEKHG----AVVNESHHDALVEDIFDKEDEDKDGF 187 Query: 230 VTIDEFLETCQKDE 243 ++ EF T + DE Sbjct: 188 ISAREF--TYKHDE 199 >4Q57-A nrPDB Length = 65 Score = 31.2 bits (69), Expect = 0.48, Method: Compositional matrix adjust. Identities = 20/72 (27%), Positives = 38/72 (52%), Gaps = 14/72 (19%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLE-HVERFFQKMDR 224 + K AF+L+D + DG IT +E+ +M+S +G++ P E ++ ++D Sbjct: 3 EFKEAFSLFDKDGDGTITTKELGTVMRS----LGQN---------PTEAELQDMINEVDA 49 Query: 225 NQDGVVTIDEFL 236 + +G + EFL Sbjct: 50 DGNGTIDFPEFL 61 >5H7D-E nrPDB Length = 120 Score = 31.2 bits (69), Expect = 0.49, Method: Compositional matrix adjust. Identities = 20/73 (27%), Positives = 38/73 (52%), Gaps = 14/73 (19%) Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLE-HVERFFQKMD 223 + K AF+L+D + DG IT +E+ +M+S +G++ P E ++ ++D Sbjct: 56 QAFKEAFSLFDKDGDGTITTKELGTVMRS----LGQN---------PTEAELQDMINEVD 102 Query: 224 RNQDGVVTIDEFL 236 + +G + EFL Sbjct: 103 ADGNGTIDFPEFL 115 Score = 27.3 bits (59), Expect = 6.8, Method: Compositional matrix adjust. Identities = 16/57 (28%), Positives = 27/57 (47%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIM 191 F+ FD DG+G I ++ + L + +L+ N D + +G I E L +M Sbjct: 62 FSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMM 118 >2RO9-A nrPDB Length = 69 Score = 31.2 bits (69), Expect = 0.50, Method: Compositional matrix adjust. Identities = 20/73 (27%), Positives = 35/73 (47%), Gaps = 12/73 (16%) Query: 164 HEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMD 223 E+LK AF ++D +++G I+ E+ RH L E E V+ ++ D Sbjct: 3 EEELKEAFRVFDKDQNGFISAAEL------------RHVMTNLGEKLTDEEVDEMIREAD 50 Query: 224 RNQDGVVTIDEFL 236 + DG + +EF+ Sbjct: 51 VDGDGQINYEEFV 63 >5OTJ-D nrPDB Length = 110 Score = 31.2 bits (69), Expect = 0.51, Method: Compositional matrix adjust. Identities = 16/84 (19%), Positives = 37/84 (44%), Gaps = 13/84 (15%) Query: 163 VHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKM 222 + + ++ F +D N DG I+ E+ ++++ + V+R ++ Sbjct: 1 MADDMERIFKRFDTNGDGKISLSELTDALRTLGS-------------TSADEVQRMMAEI 47 Query: 223 DRNQDGVVTIDEFLETCQKDENIM 246 D + DG + +EF+ C + +M Sbjct: 48 DTDGDGFIDFNEFISFCNANPGLM 71 >3I5H-B nrPDB Length = 153 Score = 30.8 bits (68), Expect = 0.52, Method: Compositional matrix adjust. Identities = 30/143 (20%), Positives = 67/143 (46%), Gaps = 12/143 (8%) Query: 85 QTKFTKKELQSLYRGFK--NECPTGLVDEDTFKLIYSQF--FPQGDATTYAHFLFNAFDA 140 + K +++++Q L F ++ G + + K ++S P D NA Sbjct: 7 RVKLSQRQMQELKEAFTMIDQDRDGFIGMEDLKDMFSSLGRVPPDDE-------LNAMLK 59 Query: 141 DGNGAIHFEDFVVGLSILLRGTVHEK-LKWAFNLYDINKDGCITKEEMLAIMKSIYDMMG 199 + G ++F F+ + GT E L+ AF+++D + G I ++ + +++++ D Sbjct: 60 ECPGQLNFTAFLTLFGEKVSGTDPEDALRNAFSMFDEDGQGFIPEDYLKDLLENMGDNFS 119 Query: 200 RHTYPILREDAPLEHVERFFQKM 222 + + +DAPL++ + + KM Sbjct: 120 KEEIKNVWKDAPLKNKQFNYNKM 142 >3IFK-A nrPDB Length = 90 Score = 30.8 bits (68), Expect = 0.55, Method: Compositional matrix adjust. Identities = 20/72 (27%), Positives = 38/72 (52%), Gaps = 14/72 (19%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLE-HVERFFQKMDR 224 + K AF+L+D + DG IT +E+ +M+S+ G++ P E ++ ++D Sbjct: 11 EFKEAFSLFDKDGDGTITTKELGTVMRSL----GQN---------PTEAELQDMINEVDA 57 Query: 225 NQDGVVTIDEFL 236 + +G + EFL Sbjct: 58 DGNGTIDFPEFL 69 Score = 30.4 bits (67), Expect = 0.70, Method: Compositional matrix adjust. Identities = 14/39 (35%), Positives = 24/39 (61%), Gaps = 1/39 (2%) Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGT-VHEKLKWAF 171 + N DADGNG I F +F+ ++ ++ T E+++ AF Sbjct: 51 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAF 89 Score = 27.7 bits (60), Expect = 4.9, Method: Compositional matrix adjust. Identities = 16/57 (28%), Positives = 27/57 (47%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIM 191 F+ FD DG+G I ++ + L + +L+ N D + +G I E L +M Sbjct: 16 FSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMM 72 >2AMI-A nrPDB Length = 96 Score = 30.8 bits (68), Expect = 0.65, Method: Compositional matrix adjust. Identities = 18/57 (31%), Positives = 28/57 (49%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIM 191 F+ FD DG+G I ++ V + L E++K + D + G I EE L +M Sbjct: 36 FDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMISEIDKDGSGTIDFEEFLTMM 92 Score = 28.5 bits (62), Expect = 3.0, Method: Compositional matrix adjust. Identities = 15/73 (20%), Positives = 36/73 (49%), Gaps = 12/73 (16%) Query: 164 HEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMD 223 ++++ AF+L+D + G I +E+ M++ L + E +++ ++D Sbjct: 29 KQEIREAFDLFDTDGSGTIDAKELKVAMRA------------LGFEPKKEEIKKMISEID 76 Query: 224 RNQDGVVTIDEFL 236 ++ G + +EFL Sbjct: 77 KDGSGTIDFEEFL 89 >2HPS-A nrPDB Length = 186 Score = 30.4 bits (67), Expect = 0.70, Method: Compositional matrix adjust. Identities = 16/65 (24%), Positives = 30/65 (46%) Query: 127 ATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEE 186 A + +++ D D +G + +F L + +K FN D NK+G I+++E Sbjct: 100 AVIQSLIMYDCIDTDKDGYVSLPEFKAFLQAVGPDLTDDKAITCFNTLDFNKNGQISRDE 159 Query: 187 MLAIM 191 L + Sbjct: 160 FLVTV 164 >3LCP-C nrPDB Length = 93 Score = 30.4 bits (67), Expect = 0.71, Method: Compositional matrix adjust. Identities = 14/70 (20%), Positives = 33/70 (47%) Query: 171 FNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVV 230 F ++D + + + E+ + ++ G P++ ED + ++ + D+N DG + Sbjct: 24 FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRDDDKNNDGYI 83 Query: 231 TIDEFLETCQ 240 EF ++ Q Sbjct: 84 DYAEFAKSLQ 93 >2VRG-A nrPDB Length = 124 Score = 30.4 bits (67), Expect = 0.71, Method: Compositional matrix adjust. Identities = 14/70 (20%), Positives = 33/70 (47%) Query: 171 FNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVV 230 F ++D + + + E+ + ++ G P++ ED + ++ + D+N DG + Sbjct: 55 FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRDDDKNNDGYI 114 Query: 231 TIDEFLETCQ 240 EF ++ Q Sbjct: 115 DYAEFAKSLQ 124 >5COC-A nrPDB Length = 130 Score = 30.4 bits (67), Expect = 0.73, Method: Compositional matrix adjust. Identities = 20/72 (27%), Positives = 38/72 (52%), Gaps = 14/72 (19%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLE-HVERFFQKMDR 224 + K AF+L+D + DG IT +E+ +M+S +G++ P E ++ ++D Sbjct: 64 EFKEAFSLFDKDGDGTITTKELGTVMRS----LGQN---------PTEAELQDMINEVDA 110 Query: 225 NQDGVVTIDEFL 236 + +G + EFL Sbjct: 111 DGNGTIDFPEFL 122 Score = 27.3 bits (59), Expect = 7.2, Method: Compositional matrix adjust. Identities = 16/57 (28%), Positives = 27/57 (47%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIM 191 F+ FD DG+G I ++ + L + +L+ N D + +G I E L +M Sbjct: 69 FSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMM 125 >5AQM-B nrPDB Length = 118 Score = 30.4 bits (67), Expect = 0.73, Method: Compositional matrix adjust. Identities = 14/45 (31%), Positives = 26/45 (57%) Query: 56 APQGSDSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGF 100 P GS+S E+EL ++H + ++++ Q + KEL + +GF Sbjct: 1 GPLGSNSPQEEVELKKLKHLEKSVEKIADQLEELNKELTGIQQGF 45 >1NYA-A nrPDB Length = 176 Score = 30.4 bits (67), Expect = 0.84, Method: Compositional matrix adjust. Identities = 31/139 (22%), Positives = 57/139 (41%), Gaps = 14/139 (10%) Query: 78 GLDQLQAQTKFTKKELQSLYRGFKNECPTG----LVDEDTFKLIYSQFFPQGDAT----- 128 G D A+ + K L+ E G L +E ++ + F QG+A+ Sbjct: 41 GKDAGAAEVQTLKNAFGGLFDYLAKEAGVGSDGSLTEEQFIRVTENLIFEQGEASFNRVL 100 Query: 129 -TYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEM 187 + D + +G I+ ++F L+ L G + AFN D N +G ++ +E+ Sbjct: 101 GPVVKGIVGMCDKNADGQINADEFAAWLTAL--GMSKAEAAEAFNQVDTNGNGELSLDEL 158 Query: 188 LAIMKSIYDMMGRHTYPIL 206 L ++ + GR +L Sbjct: 159 LTAVRDFH--FGRLDVELL 175 Score = 30.0 bits (66), Expect = 1.1, Method: Compositional matrix adjust. Identities = 30/116 (25%), Positives = 50/116 (43%), Gaps = 19/116 (16%) Query: 135 FNAFDADGNGAIHFEDF-------VVGLSILLRGTVHEKLKWAF-NLYD-------INKD 179 F+ +D DGNGA+ DF + LK AF L+D + D Sbjct: 13 FDRWDFDGNGALERADFEKEAQHIAEAFGKDAGAAEVQTLKNAFGGLFDYLAKEAGVGSD 72 Query: 180 GCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEF 235 G +T+E+ + + +++ G ++ R P+ V+ D+N DG + DEF Sbjct: 73 GSLTEEQFIRVTENLIFEQGEASFN--RVLGPV--VKGIVGMCDKNADGQINADEF 124 >2B1U-A nrPDB Length = 71 Score = 30.4 bits (67), Expect = 0.86, Method: Composition-based stats. Identities = 21/71 (29%), Positives = 33/71 (46%), Gaps = 12/71 (16%) Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDR 224 E L+ AF +D + DG IT +E+ R L + P E ++ ++ D Sbjct: 6 EDLQVAFRAFDQDGDGHITVDEL------------RRAMAGLGQPLPQEELDAMIREADV 53 Query: 225 NQDGVVTIDEF 235 +QDG V +EF Sbjct: 54 DQDGRVNYEEF 64 Score = 28.9 bits (63), Expect = 2.2, Method: Composition-based stats. Identities = 16/57 (28%), Positives = 29/57 (50%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIM 191 F AFD DG+G I ++ ++ L + E+L D+++DG + EE ++ Sbjct: 12 FRAFDQDGDGHITVDELRRAMAGLGQPLPQEELDAMIREADVDQDGRVNYEEFARML 68 >1TNP-A nrPDB Length = 90 Score = 30.4 bits (67), Expect = 0.87, Method: Compositional matrix adjust. Identities = 18/57 (31%), Positives = 27/57 (47%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIM 191 F+ FDADG G I ++ + +L + E+L D + G I EE L +M Sbjct: 26 FDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGTIDFEEFLVMM 82 Score = 29.3 bits (64), Expect = 1.8, Method: Compositional matrix adjust. Identities = 16/71 (22%), Positives = 37/71 (52%), Gaps = 12/71 (16%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRN 225 + K AF+++D + G I+ +E+ +M+ M+G++ E ++ +++D + Sbjct: 21 EFKAAFDMFDADGGGDISTKELGTVMR----MLGQNPTK--------EELDAIIEEVDED 68 Query: 226 QDGVVTIDEFL 236 G + +EFL Sbjct: 69 GSGTIDFEEFL 79 >5LS0-A nrPDB Length = 179 Score = 30.4 bits (67), Expect = 0.88, Method: Compositional matrix adjust. Identities = 14/45 (31%), Positives = 24/45 (53%) Query: 212 LEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQLFENVI 256 L + RFF+ +N++ V +++FL + E I SM L+ I Sbjct: 133 LSEIRRFFEDYKKNENKEVAVNDFLPSESAVEAIQYSMDLYAEYI 177 >3A4U-B nrPDB Length = 143 Score = 30.0 bits (66), Expect = 0.90, Method: Compositional matrix adjust. Identities = 14/70 (20%), Positives = 33/70 (47%) Query: 171 FNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVV 230 F ++D + + + E+ + ++ G P++ ED + ++ + D+N DG + Sbjct: 74 FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRDDDKNNDGYI 133 Query: 231 TIDEFLETCQ 240 EF ++ Q Sbjct: 134 DYAEFAKSLQ 143 >1B7T-Y nrPDB Length = 156 Score = 30.0 bits (66), Expect = 1.1, Method: Compositional matrix adjust. Identities = 12/36 (33%), Positives = 27/36 (75%), Gaps = 4/36 (11%) Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGR 200 +++K AF++ D+++DG ++KE+ +K+I + +GR Sbjct: 18 QEMKEAFSMIDVDRDGFVSKED----IKAISEQLGR 49 >2LVK-A nrPDB Length = 77 Score = 30.0 bits (66), Expect = 1.1, Method: Compositional matrix adjust. Identities = 16/82 (19%), Positives = 36/82 (43%), Gaps = 13/82 (15%) Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDR 224 + ++ F +D N DG I+ E+ ++++ + V+R ++D Sbjct: 2 DDMERIFKRFDTNGDGKISLSELTDALRTLGS-------------TSADEVQRMMAEIDT 48 Query: 225 NQDGVVTIDEFLETCQKDENIM 246 + DG + +EF+ C + +M Sbjct: 49 DGDGFIDFNEFISFCNANPGLM 70 >4YGB-B nrPDB Length = 104 Score = 30.0 bits (66), Expect = 1.1, Method: Compositional matrix adjust. Identities = 14/70 (20%), Positives = 33/70 (47%) Query: 171 FNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVV 230 F ++D + + + E+ + ++ G P++ ED + ++ + D+N DG + Sbjct: 35 FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRDDDKNNDGYI 94 Query: 231 TIDEFLETCQ 240 EF ++ Q Sbjct: 95 DYAEFAKSLQ 104 >5Z1Q-A nrPDB Length = 95 Score = 29.6 bits (65), Expect = 1.2, Method: Compositional matrix adjust. Identities = 19/74 (25%), Positives = 36/74 (48%), Gaps = 14/74 (18%) Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSI-YDMMGRHTYPILREDAPLEHVERFFQKMD 223 +++K AF+L+D NK G I E+ M+++ +D+ ++ E D Sbjct: 27 QEIKEAFDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILELMNE-------------YD 73 Query: 224 RNQDGVVTIDEFLE 237 R +G + D+FL+ Sbjct: 74 REGNGYIGFDDFLD 87 Score = 27.3 bits (59), Expect = 7.1, Method: Compositional matrix adjust. Identities = 10/19 (52%), Positives = 14/19 (73%) Query: 134 LFNAFDADGNGAIHFEDFV 152 L N +D +GNG I F+DF+ Sbjct: 68 LMNEYDREGNGYIGFDDFL 86 >1DFK-Y nrPDB Length = 139 Score = 29.6 bits (65), Expect = 1.2, Method: Compositional matrix adjust. Identities = 12/36 (33%), Positives = 27/36 (75%), Gaps = 4/36 (11%) Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGR 200 +++K AF++ D+++DG ++KE+ +K+I + +GR Sbjct: 7 QEMKEAFSMIDVDRDGFVSKED----IKAISEQLGR 38 >2JOJ-A nrPDB Length = 77 Score = 29.6 bits (65), Expect = 1.4, Method: Compositional matrix adjust. Identities = 19/74 (25%), Positives = 36/74 (48%), Gaps = 14/74 (18%) Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSI-YDMMGRHTYPILREDAPLEHVERFFQKMD 223 +++K AF+L+D NK G I E+ M+++ +D+ ++ E D Sbjct: 7 QEIKEAFDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILELMNE-------------YD 53 Query: 224 RNQDGVVTIDEFLE 237 R +G + D+FL+ Sbjct: 54 REGNGYIGFDDFLD 67 >4BTS-A7 nrPDB Length = 162 Score = 29.6 bits (65), Expect = 1.4, Method: Compositional matrix adjust. Identities = 14/47 (29%), Positives = 23/47 (48%) Query: 144 GAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAI 190 G + +++ S+ RG + E W F Y +NK+GC + L I Sbjct: 36 GVPNLHCYILVRSLKDRGFLEEIFNWGFTYYYLNKEGCEYLKTKLGI 82 >1TRF-A nrPDB Length = 76 Score = 29.6 bits (65), Expect = 1.4, Method: Compositional matrix adjust. Identities = 18/57 (31%), Positives = 27/57 (47%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIM 191 F+ FDADG G I ++ + +L + E+L D + G I EE L +M Sbjct: 15 FDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGTIDFEEFLVMM 71 Score = 28.5 bits (62), Expect = 2.6, Method: Compositional matrix adjust. Identities = 16/71 (22%), Positives = 37/71 (52%), Gaps = 12/71 (16%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRN 225 + K AF+++D + G I+ +E+ +M+ M+G++ E ++ +++D + Sbjct: 10 EFKAAFDMFDADGGGDISTKELGTVMR----MLGQNPTK--------EELDAIIEEVDED 57 Query: 226 QDGVVTIDEFL 236 G + +EFL Sbjct: 58 GSGTIDFEEFL 68 >1OQP-A nrPDB Length = 77 Score = 29.6 bits (65), Expect = 1.4, Method: Compositional matrix adjust. Identities = 22/78 (28%), Positives = 34/78 (43%), Gaps = 12/78 (15%) Query: 164 HEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMD 223 E++ AF L+D + G IT I D+ R L E+ E ++ + D Sbjct: 8 REEILKAFRLFDDDNSGTIT----------IKDL--RRVAKELGENLTEEELQEMIAEAD 55 Query: 224 RNQDGVVTIDEFLETCQK 241 RN D + DEF+ +K Sbjct: 56 RNDDNEIDEDEFIRIMKK 73 Score = 27.3 bits (59), Expect = 6.6, Method: Compositional matrix adjust. Identities = 18/58 (31%), Positives = 25/58 (43%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMK 192 F FD D +G I +D L E+L+ D N D I ++E + IMK Sbjct: 15 FRLFDDDNSGTITIKDLRRVAKELGENLTEEELQEMIAEADRNDDNEIDEDEFIRIMK 72 >1TIZ-A nrPDB Length = 67 Score = 29.3 bits (64), Expect = 1.6, Method: Compositional matrix adjust. Identities = 11/25 (44%), Positives = 18/25 (72%) Query: 215 VERFFQKMDRNQDGVVTIDEFLETC 239 +R F+K D+N+DG +++DEF E Sbjct: 3 AKRVFEKFDKNKDGKLSLDEFREVA 27 >1CB1-A nrPDB Length = 78 Score = 29.3 bits (64), Expect = 1.7, Method: Compositional matrix adjust. Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 2/64 (3%) Query: 92 ELQSLYRGF--KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFE 149 EL+S++ + K P L E+ +LI ++F LF D +G+G + FE Sbjct: 8 ELKSIFEKYAAKEGDPNQLSKEELKQLIQAEFPSLLKGPRTLDDLFQELDKNGDGEVSFE 67 Query: 150 DFVV 153 +F V Sbjct: 68 EFQV 71 >1A75-A nrPDB Length = 108 Score = 29.3 bits (64), Expect = 1.7, Method: Compositional matrix adjust. Identities = 22/59 (37%), Positives = 32/59 (54%), Gaps = 8/59 (13%) Query: 100 FKNECPTGLVDEDTFKLIYSQFFPQG-----DATTYAHFLFNAFDADGNGAIHFEDFVV 153 F ++ +G ++ED KL + Q F G DA T A A D+DG+GAI E++V Sbjct: 49 FIDQDKSGFIEEDELKL-FLQVFKAGARALTDAETKA--FLKAGDSDGDGAIGVEEWVA 104 >5MWC-D nrPDB Length = 311 Score = 29.3 bits (64), Expect = 1.8, Method: Compositional matrix adjust. Identities = 26/85 (30%), Positives = 39/85 (45%), Gaps = 15/85 (17%) Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDR 224 E+L F +D + DG I +EE I+ R T L ++ P E F D Sbjct: 151 EELSECFRTFDKDGDGFIDREEFGGII--------RLTGEQLTDEDPDE----IFGDSDT 198 Query: 225 NQDGVVTIDEFLETCQKDENIMNSM 249 +++G + DEFL+ EN+ SM Sbjct: 199 DKNGRIDFDEFLKMV---ENVQLSM 220 >3MSE-B nrPDB Length = 180 Score = 29.3 bits (64), Expect = 1.8, Method: Compositional matrix adjust. Identities = 18/71 (25%), Positives = 32/71 (45%), Gaps = 14/71 (19%) Query: 175 DINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDE 234 D N +G ++ E+ ++ S+ I + D + R Q +D N G +T E Sbjct: 49 DTNHNGSLSHREIYTVLASV---------GIKKWD-----INRILQALDINDRGNITYTE 94 Query: 235 FLETCQKDENI 245 F+ C + +NI Sbjct: 95 FMAGCYRWKNI 105 >4PAL-A nrPDB Length = 108 Score = 29.3 bits (64), Expect = 1.8, Method: Compositional matrix adjust. Identities = 22/75 (29%), Positives = 34/75 (45%), Gaps = 6/75 (8%) Query: 84 AQTKFTKKELQSLYRGFK--NECPTGLVDEDTFKLIYSQFFPQGDATTYAH---FLFNAF 138 A+ K L + + F ++ +G ++ED KL F P A T A FL + Sbjct: 31 AKVGLASKSLDDVKKAFYVIDQDKSGFIEEDELKLFLQNFSPSARALTDAETKAFLADG- 89 Query: 139 DADGNGAIHFEDFVV 153 D DG+G I ++F Sbjct: 90 DKDGDGMIGVDEFAA 104 >3PAT-A nrPDB Length = 110 Score = 29.3 bits (64), Expect = 1.9, Method: Compositional matrix adjust. Identities = 21/77 (27%), Positives = 34/77 (44%), Gaps = 9/77 (11%) Query: 159 LRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERF 218 L+ +K F D + G I +EE+ ++KS + GR D + F Sbjct: 36 LKAMSANDVKKVFKAIDADASGFIEEEELKFVLKS-FAADGR--------DLTDAETKAF 86 Query: 219 FQKMDRNQDGVVTIDEF 235 + D++ DG + IDEF Sbjct: 87 LKAADKDGDGKIGIDEF 103 >1FW4-A nrPDB Length = 71 Score = 28.9 bits (63), Expect = 2.0, Method: Compositional matrix adjust. Identities = 19/74 (25%), Positives = 35/74 (47%), Gaps = 12/74 (16%) Query: 164 HEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMD 223 E+++ AF ++D + +G I+ E+ RH L E E V+ ++ D Sbjct: 5 EEEIREAFRVFDKDGNGYISAAEL------------RHVMTNLGEKLTDEEVDEMIREAD 52 Query: 224 RNQDGVVTIDEFLE 237 + DG V +EF++ Sbjct: 53 IDGDGQVNYEEFVQ 66 Score = 28.5 bits (62), Expect = 2.6, Method: Compositional matrix adjust. Identities = 17/59 (28%), Positives = 27/59 (45%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS 193 F FD DGNG I + ++ L E++ DI+ DG + EE + +M + Sbjct: 12 FRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 70 >3J04-B nrPDB Length = 143 Score = 28.9 bits (63), Expect = 2.0, Method: Compositional matrix adjust. Identities = 12/30 (40%), Positives = 21/30 (70%) Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSI 194 ++ K AFN+ D N+DG I KE++ ++ S+ Sbjct: 7 QEFKEAFNMIDQNRDGFIDKEDLHDMLASM 36 >5ZGM-A nrPDB Length = 110 Score = 28.9 bits (63), Expect = 2.5, Method: Compositional matrix adjust. Identities = 19/79 (24%), Positives = 35/79 (44%), Gaps = 9/79 (11%) Query: 157 ILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVE 216 + L+G ++K F + D ++ G I +EE+ +++K + GR D + Sbjct: 34 VGLKGKSEAQVKEVFEILDKDQSGFIEEEELKSVLKG-FSAHGR--------DLSDTETK 84 Query: 217 RFFQKMDRNQDGVVTIDEF 235 D + DG + DEF Sbjct: 85 ALLAAGDSDHDGKIGADEF 103 >2OPO-A nrPDB Length = 86 Score = 28.9 bits (63), Expect = 2.6, Method: Compositional matrix adjust. Identities = 17/80 (21%), Positives = 35/80 (43%), Gaps = 13/80 (16%) Query: 171 FNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVV 230 F +D N DG I+ E+ +K++ P + V R ++D + DG + Sbjct: 17 FKRFDTNGDGKISSSELGDALKTLG-----SVTP--------DEVRRMMAEIDTDGDGFI 63 Query: 231 TIDEFLETCQKDENIMNSMQ 250 + DEF + + + ++ + Sbjct: 64 SFDEFTDFARANRGLVKDVS 83 >5XND-A nrPDB Length = 114 Score = 28.5 bits (62), Expect = 2.8, Method: Compositional matrix adjust. Identities = 20/77 (25%), Positives = 36/77 (46%), Gaps = 9/77 (11%) Query: 159 LRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERF 218 L G +++K AF + D +K G I +EE+ +++ + L + + F Sbjct: 41 LSGKSTDEVKKAFAIIDQDKSGFIEEEELKLFLQNF-----KAGARALSD----AETKAF 91 Query: 219 FQKMDRNQDGVVTIDEF 235 + D + DG + IDEF Sbjct: 92 LKAGDSDGDGKIGIDEF 108 >2GS3-A nrPDB Length = 185 Score = 28.5 bits (62), Expect = 2.8, Method: Compositional matrix adjust. Identities = 14/40 (35%), Positives = 22/40 (55%), Gaps = 5/40 (12%) Query: 160 RGTVHEKLKWAFNLYDINKDGCITK-----EEMLAIMKSI 194 +G + +KW F + I+K+GC+ K EE L I K + Sbjct: 142 KGILGNAIKWNFTKFLIDKNGCVVKRYGPMEEPLVIEKDL 181 >5LWF-A nrPDB Length = 273 Score = 28.5 bits (62), Expect = 3.1, Method: Compositional matrix adjust. Identities = 14/33 (42%), Positives = 19/33 (57%), Gaps = 1/33 (3%) Query: 16 LGDPGRIPLSKRE-SIKWQRPRFTRQALMRCCL 47 L DPG++P KRE I W + T AL+R + Sbjct: 166 LEDPGKLPSEKRELLIDWMKRNTTGDALIRAGV 198 >1S6J-A nrPDB Length = 87 Score = 28.1 bits (61), Expect = 3.4, Method: Compositional matrix adjust. Identities = 17/56 (30%), Positives = 27/56 (48%) Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLA 189 LF D D +G I F++ GL + + ++K + DI+K G I E +A Sbjct: 28 LFKMIDTDNSGTITFDELKDGLKRVGSELMESEIKDLMDAADIDKSGTIDYGEFIA 83 >5L71-A nrPDB Length = 171 Score = 28.1 bits (61), Expect = 3.5, Method: Compositional matrix adjust. Identities = 10/25 (40%), Positives = 16/25 (64%) Query: 160 RGTVHEKLKWAFNLYDINKDGCITK 184 RG + +KW F + I+K+GC+ K Sbjct: 128 RGMLGNAIKWNFTKFLIDKNGCVVK 152 >5PAL-A nrPDB Length = 109 Score = 28.1 bits (61), Expect = 3.7, Method: Compositional matrix adjust. Identities = 19/79 (24%), Positives = 34/79 (43%), Gaps = 9/79 (11%) Query: 157 ILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVE 216 + L+G ++K F + D ++ G I +EE+ ++K + GR D + Sbjct: 33 VGLKGKTDAQVKEVFEILDKDQSGFIEEEELKGVLKG-FSAHGR--------DLNDTETK 83 Query: 217 RFFQKMDRNQDGVVTIDEF 235 D + DG + DEF Sbjct: 84 ALLAAGDSDHDGKIGADEF 102 >4LRY-C nrPDB Length = 318 Score = 28.1 bits (61), Expect = 3.9, Method: Compositional matrix adjust. Identities = 11/33 (33%), Positives = 20/33 (60%) Query: 206 LREDAPLEHVERFFQKMDRNQDGVVTIDEFLET 238 +++ PL+HVE F+ + D V+T+ +ET Sbjct: 262 IKQAHPLKHVEATFESQHQFIDAVITLKPIIET 294 >2LC5-A nrPDB Length = 151 Score = 28.1 bits (61), Expect = 4.0, Method: Compositional matrix adjust. Identities = 24/103 (23%), Positives = 47/103 (45%), Gaps = 20/103 (19%) Query: 138 FDADGNGAIHFEDFVVGLSILLRGTVH----EKLKWAFNLYDINKDGCITKEEMLAIMKS 193 +D D +G E F L+I+L E +K AF ++D K+G I+ E+ Sbjct: 59 YDKDNSGKFDQETF---LTIMLEYGQEVDSTEDIKKAFEIFDKEKNGYISASEL------ 109 Query: 194 IYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFL 236 +H L E + V+ +++ ++G++ +D+F+ Sbjct: 110 ------KHVLTTLGEKLTEQEVDDLLKEIGV-EEGLINVDDFV 145 >3JPZ-A nrPDB Length = 366 Score = 28.1 bits (61), Expect = 4.2, Method: Compositional matrix adjust. Identities = 15/39 (38%), Positives = 20/39 (51%) Query: 148 FEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEE 186 FED VV L + RGT E ++YDI+ + K E Sbjct: 295 FEDIVVALQLQKRGTGGEHTAAVDDVYDISNAARLKKSE 333 >2M5E-A nrPDB Length = 73 Score = 27.7 bits (60), Expect = 4.9, Method: Compositional matrix adjust. Identities = 18/59 (30%), Positives = 27/59 (45%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS 193 F FD DGNG I + ++ L +++ DI+ DG I EE + +M S Sbjct: 14 FKVFDRDGNGLISAAELRHVMTNLGEKLTDDEVDEMIREADIDGDGHINYEEFVRMMVS 72 >1Y1X-A nrPDB Length = 191 Score = 27.7 bits (60), Expect = 5.0, Method: Compositional matrix adjust. Identities = 22/66 (33%), Positives = 29/66 (43%), Gaps = 6/66 (9%) Query: 135 FNAFDADGNGAIHFEDFVVGLS---ILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIM 191 F A D DG+GAI + LS + EKL ++YD N G IT +E + Sbjct: 33 FRAVDTDGSGAISVPELNAALSSAGVPFSLATTEKL---LHMYDKNHSGEITFDEFKDLH 89 Query: 192 KSIYDM 197 I M Sbjct: 90 HFILSM 95 >6AGH-A nrPDB Length = 339 Score = 27.7 bits (60), Expect = 5.6, Method: Compositional matrix adjust. Identities = 9/27 (33%), Positives = 18/27 (66%) Query: 167 LKWAFNLYDINKDGCITKEEMLAIMKS 193 L F ++D++ D C++ EE L ++K+ Sbjct: 308 LDTVFKIFDLDGDECLSHEEFLGVLKN 334 >1QX2-A nrPDB Length = 76 Score = 27.3 bits (59), Expect = 5.8, Method: Compositional matrix adjust. Identities = 22/80 (27%), Positives = 44/80 (55%), Gaps = 14/80 (17%) Query: 165 EKLKWAFNLYDINKDG---CITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQK 221 E++K AF ++ K+G I+KEE+ +M+++ P L + + ++ ++ Sbjct: 5 EEIKGAFEVF-AAKEGDPNQISKEELKLVMQTLG--------PSLLKG--MSTLDEMIEE 53 Query: 222 MDRNQDGVVTIDEFLETCQK 241 +D+N DG V+ +EFL +K Sbjct: 54 VDKNGDGEVSFEEFLVMMKK 73 >1T70-A nrPDB Length = 255 Score = 27.3 bits (59), Expect = 5.9, Method: Compositional matrix adjust. Identities = 14/37 (37%), Positives = 19/37 (51%), Gaps = 3/37 (8%) Query: 180 GCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVE 216 GC+T K IY M+ TYPI+R PL + + Sbjct: 59 GCLTLGNHAWHHKDIYPMLSEDTYPIVR---PLNYAD 92 >3DTP-E nrPDB Length = 196 Score = 27.3 bits (59), Expect = 7.0, Method: Compositional matrix adjust. Identities = 13/36 (36%), Positives = 23/36 (63%), Gaps = 4/36 (11%) Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGR 200 ++ K AF L D +KDG I+K + +++ +D +GR Sbjct: 57 QEFKEAFQLIDQDKDGFISKND----IRATFDSLGR 88 >3KPX-A nrPDB Length = 198 Score = 27.3 bits (59), Expect = 7.1, Method: Compositional matrix adjust. Identities = 18/55 (32%), Positives = 30/55 (54%), Gaps = 2/55 (3%) Query: 168 KWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKM 222 K+ FN DIN +G IT +E+++ K+ D+ + + E VE FF+K+ Sbjct: 26 KFMFNFLDINGNGKITLDEIVS--KASDDICAKLGATPAQTQRHQEAVEAFFKKI 78 >2KZ2-A nrPDB Length = 94 Score = 26.9 bits (58), Expect = 8.0, Method: Compositional matrix adjust. Identities = 19/74 (25%), Positives = 34/74 (45%), Gaps = 12/74 (16%) Query: 164 HEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMD 223 E+++ AF + D + +G I+ E+ RH L E E V+ ++ D Sbjct: 28 EEEIREAFRVEDKDGNGYISAAEL------------RHVMTNLGEKLTDEEVDEMIREAD 75 Query: 224 RNQDGVVTIDEFLE 237 + DG V +EF++ Sbjct: 76 IDGDGQVNYEEFVQ 89 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2JUL-A nrPDB 379 e-106 3DD4-A nrPDB 249 9e-67 1S1E-A nrPDB 248 1e-66 1S6C-A nrPDB 238 2e-63 2LCP-A nrPDB 232 9e-62 5T7C-A nrPDB 230 4e-61 1BJF-A nrPDB 229 1e-60 2L2E-A nrPDB 228 2e-60 5M6C-E nrPDB 223 5e-59 2JU0-A nrPDB 219 1e-57 6EPA-A nrPDB 207 4e-54 2I94-A nrPDB 188 2e-48 2D8N-A nrPDB 185 2e-47 2R2I-A nrPDB 172 1e-43 1JBA-A nrPDB 169 2e-42 2NA0-A nrPDB 165 1e-41 2GGZ-A nrPDB 164 3e-41 1V1G-A nrPDB 150 5e-37 5YPX-A nrPDB 147 4e-36 2ZFD-A nrPDB 145 1e-35 4IL1-A nrPDB 143 7e-35 1UHN-A nrPDB 141 2e-34 3NCG-A nrPDB 138 3e-33 3U0K-A nrPDB 136 9e-33 2LM5-A nrPDB 136 9e-33 3EK4-A nrPDB 136 1e-32 4OY4-A nrPDB 135 1e-32 4ORC-B nrPDB 134 3e-32 2E6W-A nrPDB 131 4e-31 5B8I-B nrPDB 130 4e-31 5UKG-A nrPDB 125 1e-29 3WFN-B nrPDB 125 2e-29 4I2Y-A nrPDB 125 2e-29 2N6A-A nrPDB 123 7e-29 6O20-F nrPDB 122 2e-28 2F2P-A nrPDB 121 3e-28 4E53-A nrPDB 119 1e-27 6HCS-A nrPDB 119 1e-27 5I0I-E nrPDB 118 3e-27 2E30-A nrPDB 113 1e-25 5A2H-A nrPDB 113 1e-25 1CLM-A nrPDB 112 1e-25 1GGZ-A nrPDB 109 1e-24 2L1W-A nrPDB 102 1e-22 4JWQ-A nrPDB 102 2e-22 1TOP-A nrPDB 102 2e-22 2TN4-A nrPDB 101 4e-22 2JNF-A nrPDB 100 5e-22 3K21-A nrPDB 100 8e-22 1DTL-A nrPDB 99 1e-21 3O4Y-A nrPDB 99 2e-21 2BEC-A nrPDB 99 2e-21 3Q5I-A nrPDB 94 5e-20 2BL0-C nrPDB 92 2e-19 2JNX-A nrPDB 81 5e-16 2HF5-A nrPDB 79 2e-15 5ZOR-A nrPDB 78 4e-15 1JFJ-A nrPDB 76 1e-14 2M29-A nrPDB 76 2e-14 5E37-A nrPDB 72 3e-13 1JC2-A nrPDB 68 4e-12 3QRX-A nrPDB 66 1e-11 2KSZ-A nrPDB 60 7e-10 1SNL-A nrPDB 53 1e-07 Sequences not found previously or not previously below threshold: 1DGU-A nrPDB 121 2e-28 4RGJ-A nrPDB 99 2e-21 5JN2-A nrPDB 97 8e-21 3HZT-A nrPDB 96 2e-20 4YZB-A nrPDB 96 2e-20 3LIJ-A nrPDB 95 3e-20 1S6I-A nrPDB 92 2e-19 2AAO-A nrPDB 90 1e-18 2LMV-A nrPDB 89 2e-18 4MVF-A nrPDB 89 2e-18 2LHI-A nrPDB 88 4e-18 4DS7-A nrPDB 87 7e-18 1LKJ-A nrPDB 84 5e-17 5D43-A nrPDB 83 1e-16 3KHE-A nrPDB 82 2e-16 3PM8-A nrPDB 81 3e-16 2LAP-A nrPDB 81 4e-16 2GGM-A nrPDB 81 4e-16 3L19-A nrPDB 81 4e-16 2OBH-A nrPDB 77 7e-15 5MWC-D nrPDB 74 9e-14 2LHH-A nrPDB 73 1e-13 1FW4-A nrPDB 73 1e-13 2KN2-A nrPDB 72 2e-13 3E3R-A nrPDB 72 2e-13 2RO9-A nrPDB 70 9e-13 3FWC-A nrPDB 70 1e-12 2KZ2-A nrPDB 70 1e-12 2ROB-A nrPDB 69 2e-12 2M5E-A nrPDB 69 2e-12 1OZS-A nrPDB 66 2e-11 2LV7-A nrPDB 65 4e-11 2LC5-A nrPDB 63 1e-10 2K7C-A nrPDB 62 2e-10 2B1U-A nrPDB 62 2e-10 3KF9-A nrPDB 62 2e-10 2M97-A nrPDB 62 3e-10 5H7D-E nrPDB 62 3e-10 5OTJ-D nrPDB 61 4e-10 5COC-A nrPDB 61 5e-10 4WPX-A nrPDB 61 5e-10 3IFK-A nrPDB 60 1e-09 2K2A-A nrPDB 60 1e-09 2LVK-A nrPDB 60 1e-09 4Q57-A nrPDB 59 2e-09 2I08-A nrPDB 59 3e-09 2RO8-A nrPDB 58 3e-09 4ZCV-A nrPDB 58 5e-09 4N5X-A nrPDB 57 5e-09 2AMI-A nrPDB 57 5e-09 3AAJ-A nrPDB 57 1e-08 1C7W-A nrPDB 56 1e-08 4YGB-B nrPDB 56 1e-08 3LCP-C nrPDB 56 2e-08 1M39-A nrPDB 56 2e-08 2VRG-A nrPDB 56 2e-08 3A4U-B nrPDB 55 2e-08 2G9B-A nrPDB 55 2e-08 3J04-B nrPDB 55 3e-08 2BL0-B nrPDB 54 5e-08 5ZGM-A nrPDB 54 6e-08 1OQP-A nrPDB 54 6e-08 1YX7-A nrPDB 54 6e-08 1Y1X-A nrPDB 54 8e-08 5PAL-A nrPDB 53 1e-07 1TRF-A nrPDB 53 1e-07 5JOJ-A nrPDB 53 1e-07 1JUO-A nrPDB 53 1e-07 5JOL-A nrPDB 53 2e-07 1H4B-A nrPDB 53 2e-07 1TNP-A nrPDB 52 2e-07 2OPO-A nrPDB 52 2e-07 2Q4U-A nrPDB 52 2e-07 5MRA-A nrPDB 52 2e-07 2I18-A nrPDB 52 2e-07 3I5H-B nrPDB 52 3e-07 2M8U-A nrPDB 52 3e-07 6IIE-A nrPDB 52 3e-07 5XND-A nrPDB 51 4e-07 6MI5-X nrPDB 51 4e-07 4P5W-A nrPDB 51 5e-07 5VLN-A nrPDB 51 5e-07 2N7L-C nrPDB 50 7e-07 4P5X-A nrPDB 50 9e-07 5TBY-E nrPDB 50 1e-06 1F55-A nrPDB 50 1e-06 2K2I-A nrPDB 49 1e-06 2KYF-A nrPDB 49 2e-06 1GJY-A nrPDB 49 2e-06 2NCO-A nrPDB 49 3e-06 4GJF-A nrPDB 48 5e-06 1W7I-B nrPDB 48 5e-06 3TZ1-A nrPDB 48 5e-06 2HPS-A nrPDB 48 5e-06 3DTP-E nrPDB 48 5e-06 3PAT-A nrPDB 47 5e-06 4NSC-A nrPDB 47 6e-06 3KPX-A nrPDB 47 7e-06 5XOP-A nrPDB 47 7e-06 1O1A-B nrPDB 47 8e-06 1SR6-C nrPDB 47 8e-06 1ZMZ-A nrPDB 47 8e-06 1I84-U nrPDB 47 8e-06 2MA2-A nrPDB 47 1e-05 4NQG-A nrPDB 47 1e-05 3SIA-A nrPDB 46 1e-05 1RTP-1 nrPDB 46 1e-05 3AKA-A nrPDB 46 1e-05 1QX2-A nrPDB 46 2e-05 1JF0-A nrPDB 46 2e-05 1RK9-A nrPDB 46 2e-05 6EAZ-A nrPDB 46 2e-05 1QXP-A nrPDB 45 2e-05 2KQY-A nrPDB 45 2e-05 5E1J-A nrPDB 45 2e-05 5H53-C nrPDB 45 2e-05 2K7B-A nrPDB 45 3e-05 1TTX-A nrPDB 45 3e-05 1A75-A nrPDB 45 3e-05 1S36-A nrPDB 45 4e-05 2M7M-A nrPDB 44 5e-05 1GGW-A nrPDB 44 5e-05 5ZH6-A nrPDB 44 5e-05 1S6J-A nrPDB 44 5e-05 4D1E-A nrPDB 44 5e-05 4L9M-A nrPDB 44 5e-05 4I5L-B nrPDB 44 6e-05 3MSE-B nrPDB 44 6e-05 4MSP-A nrPDB 44 6e-05 1IJ5-A nrPDB 44 6e-05 4OKH-A nrPDB 44 7e-05 5H53-B nrPDB 44 7e-05 4PAL-A nrPDB 44 8e-05 1NYA-A nrPDB 44 8e-05 1SL8-A nrPDB 44 8e-05 4MEW-A nrPDB 44 9e-05 6AGH-A nrPDB 44 9e-05 5CPV-A nrPDB 44 9e-05 1G33-A nrPDB 43 1e-04 1F4Q-A nrPDB 43 1e-04 5B7X-A nrPDB 43 1e-04 5Z1Q-A nrPDB 43 1e-04 2NLN-A nrPDB 43 1e-04 1B7T-Y nrPDB 43 1e-04 2SAS-A nrPDB 43 1e-04 1UHK-A nrPDB 43 1e-04 2JOJ-A nrPDB 42 2e-04 3JAX-C nrPDB 42 2e-04 5VE9-A nrPDB 42 2e-04 1N2D-A nrPDB 42 3e-04 1BU3-A nrPDB 42 3e-04 2LVV-A nrPDB 42 4e-04 1SJJ-A nrPDB 41 4e-04 6FSA-D nrPDB 41 5e-04 5TBY-C nrPDB 41 5e-04 2OS8-B nrPDB 41 6e-04 1DFK-Y nrPDB 40 8e-04 3BOW-B nrPDB 40 0.001 3I5I-C nrPDB 40 0.001 3CS1-A nrPDB 40 0.001 1TIZ-A nrPDB 40 0.001 1KFU-L nrPDB 40 0.001 2M1U-A nrPDB 39 0.001 3JBH-C nrPDB 39 0.002 4I5K-A nrPDB 39 0.002 5I2L-A nrPDB 39 0.002 3DF0-A nrPDB 39 0.002 2FCE-A nrPDB 39 0.002 5VT9-A nrPDB 39 0.002 1KFX-S nrPDB 39 0.002 2PMY-A nrPDB 39 0.002 2MBX-A nrPDB 39 0.002 1BOD-A nrPDB 39 0.002 2LUC-A nrPDB 39 0.003 4OCI-A nrPDB 38 0.004 2N8Y-A nrPDB 38 0.004 1ZFS-A nrPDB 38 0.004 3A8R-A nrPDB 38 0.004 2W4G-C nrPDB 38 0.005 2L50-A nrPDB 37 0.006 2KGR-A nrPDB 37 0.007 1Q80-A nrPDB 37 0.007 1CB1-A nrPDB 37 0.008 1NP8-A nrPDB 36 0.013 2EC6-B nrPDB 36 0.015 1NSH-A nrPDB 36 0.015 2L0P-A nrPDB 36 0.017 3TS5-B nrPDB 36 0.020 6DS2-B nrPDB 35 0.023 5HYD-A nrPDB 35 0.024 5W1A-B nrPDB 35 0.027 1QLS-A nrPDB 35 0.027 5HLO-A nrPDB 35 0.030 2WCE-A nrPDB 35 0.036 1KQV-A nrPDB 35 0.042 2Y5I-A nrPDB 34 0.059 2VTG-A nrPDB 34 0.084 5CSF-A nrPDB 34 0.090 4HRG-A nrPDB 34 0.090 6AGI-A nrPDB 34 0.092 2MJW-B nrPDB 34 0.094 4FTG-A nrPDB 34 0.096 3H4S-E nrPDB 32 0.18 4AOM-A nrPDB 32 0.20 2MHH-A nrPDB 32 0.20 2JXC-A nrPDB 32 0.22 5LXV-B nrPDB 32 0.30 2AUC-A nrPDB 32 0.30 1FI6-A nrPDB 32 0.33 5MKE-A nrPDB 32 0.33 6D1W-A nrPDB 32 0.36 2JQ6-A nrPDB 31 0.50 3FSR-A nrPDB 31 0.58 3FPC-A nrPDB 31 0.58 1YKF-A nrPDB 31 0.58 6DU8-A nrPDB 31 0.67 3DFA-A nrPDB 30 0.68 3RNC-B nrPDB 30 0.70 2KFH-A nrPDB 30 0.71 2Y3N-B nrPDB 30 0.76 4OUN-A nrPDB 30 0.79 6J79-A nrPDB 30 1.00 6QAA-A nrPDB 30 1.0 1WY9-A nrPDB 30 1.0 4C0K-A nrPDB 30 1.1 1ZQ1-C nrPDB 30 1.1 4YBH-B nrPDB 30 1.1 2KHN-A nrPDB 29 1.6 4PCW-A nrPDB 29 1.7 5X2E-A nrPDB 29 1.7 2L5Y-A nrPDB 29 1.8 5MVF-A nrPDB 29 2.1 4WR2-A nrPDB 29 2.5 2V9K-A nrPDB 29 2.6 2QPT-A nrPDB 29 2.7 6HIV-CJ nrPDB 28 3.8 2JTT-A nrPDB 28 3.9 1DJX-A nrPDB 28 4.1 4DUQ-A nrPDB 28 4.5 3X0D-A nrPDB 28 4.8 3NSO-A nrPDB 28 5.2 3QR0-A nrPDB 28 5.6 6F8L-G nrPDB 27 6.4 1C07-A nrPDB 27 6.6 4GFT-A nrPDB 27 7.0 2GS4-A nrPDB 27 7.3 1YX2-A nrPDB 27 7.7 5COV-A nrPDB 27 8.5 2G2B-A nrPDB 27 8.6 1XOC-A nrPDB 27 8.7 5VP3-A nrPDB 27 8.9 5LPU-C nrPDB 27 9.0 2KLD-A nrPDB 27 9.2 5NRK-B nrPDB 27 9.9 >2JUL-A nrPDB Length = 256 Score = 379 bits (972), Expect = e-106, Method: Composition-based stats. Identities = 256/256 (100%), Positives = 256/256 (100%) Query: 1 MQRTKEAVKASDGNLLGDPGRIPLSKRESIKWQRPRFTRQALMRCCLIKWILSSAAPQGS 60 MQRTKEAVKASDGNLLGDPGRIPLSKRESIKWQRPRFTRQALMRCCLIKWILSSAAPQGS Sbjct: 1 MQRTKEAVKASDGNLLGDPGRIPLSKRESIKWQRPRFTRQALMRCCLIKWILSSAAPQGS 60 Query: 61 DSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQ 120 DSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQ Sbjct: 61 DSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQ 120 Query: 121 FFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDG 180 FFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDG Sbjct: 121 FFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDG 180 Query: 181 CITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQ 240 CITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQ Sbjct: 181 CITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQ 240 Query: 241 KDENIMNSMQLFENVI 256 KDENIMNSMQLFENVI Sbjct: 241 KDENIMNSMQLFENVI 256 >3DD4-A nrPDB Length = 229 Score = 249 bits (635), Expect = 9e-67, Method: Composition-based stats. Identities = 155/196 (79%), Positives = 178/196 (90%) Query: 61 DSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQ 120 DS + ELE++TVRH+PE L+ L+AQ+KFTKKELQ LYRGFKNECP+G+V+E+TFK IYSQ Sbjct: 34 DSVEDELEMATVRHRPEALELLEAQSKFTKKELQILYRGFKNECPSGVVNEETFKEIYSQ 93 Query: 121 FFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDG 180 FFPQGD+TTYAHFLFNAFD D NGA+ FEDF+ GLSILLRGTV EKL WAFNLYDINKDG Sbjct: 94 FFPQGDSTTYAHFLFNAFDTDHNGAVSFEDFIKGLSILLRGTVQEKLNWAFNLYDINKDG 153 Query: 181 CITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQ 240 ITKEEML IMK+IYDMMG+ TYP+L+EDAP +HVE FFQKMD+N+DGVVTIDEF+E+CQ Sbjct: 154 YITKEEMLDIMKAIYDMMGKCTYPVLKEDAPRQHVETFFQKMDKNKDGVVTIDEFIESCQ 213 Query: 241 KDENIMNSMQLFENVI 256 KDENIM SMQLFENVI Sbjct: 214 KDENIMRSMQLFENVI 229 >1S1E-A nrPDB Length = 224 Score = 248 bits (634), Expect = 1e-66, Method: Composition-based stats. Identities = 136/196 (69%), Positives = 172/196 (87%) Query: 61 DSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQ 120 D + ELE++ V H+PEGL+QL+AQT FTK+ELQ LYRGFKNECP+G+V+E+TFK IY+Q Sbjct: 21 DKIEDELEMTMVCHRPEGLEQLEAQTNFTKRELQVLYRGFKNECPSGVVNEETFKQIYAQ 80 Query: 121 FFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDG 180 FFP GDA+TYAH+LFNAFD G++ FEDFV LSILLRGTVHEKL+W FNLYDINKDG Sbjct: 81 FFPHGDASTYAHYLFNAFDTTQTGSVKFEDFVTALSILLRGTVHEKLRWTFNLYDINKDG 140 Query: 181 CITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQ 240 I KEEM+ I+K+IYDMMG++TYP+L+ED P +HV+ FFQKMD+N+DG+VT+DEFLE+CQ Sbjct: 141 YINKEEMMDIVKAIYDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLESCQ 200 Query: 241 KDENIMNSMQLFENVI 256 +D+NIM S+QLF+NV+ Sbjct: 201 EDDNIMRSLQLFQNVM 216 >1S6C-A nrPDB Length = 183 Score = 238 bits (606), Expect = 2e-63, Method: Composition-based stats. Identities = 131/183 (71%), Positives = 164/183 (89%) Query: 74 HQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHF 133 H+PEGL+QL+AQT FTK+ELQ LYRGFKNECP+G+V+E+TFK IY+QFFP GDA+TYAH+ Sbjct: 1 HRPEGLEQLEAQTNFTKRELQVLYRGFKNECPSGVVNEETFKQIYAQFFPHGDASTYAHY 60 Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS 193 LFNAFD G++ FEDFV LSILLRGTVHEKL+W FNLYDINKDG I KEEM+ I+K+ Sbjct: 61 LFNAFDTTQTGSVKFEDFVTALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKA 120 Query: 194 IYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQLFE 253 IYDMMG++TYP+L+ED P +HV+ FFQKMD+N+DG+VT+DEFLE+CQ+D+NIM S+QLF+ Sbjct: 121 IYDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLESCQEDDNIMRSLQLFQ 180 Query: 254 NVI 256 NV+ Sbjct: 181 NVM 183 >2LCP-A nrPDB Length = 190 Score = 232 bits (592), Expect = 9e-62, Method: Composition-based stats. Identities = 80/190 (42%), Positives = 124/190 (65%) Query: 67 LELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGD 126 + S + +PE +++L +T FT+KE+Q Y+GF +CP+G +D F+ IY QFFP GD Sbjct: 1 MGKSNSKLKPEVVEELTRKTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGD 60 Query: 127 ATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEE 186 T +A F+FN FD + +G I F +F+ LS+ RGT+ EKL+WAF LYD++ DG IT+ E Sbjct: 61 PTKFATFVFNVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNE 120 Query: 187 MLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIM 246 ML I+ +IY M+G E+ P + V+R F MD+N DG +T+ EF E + D +I+ Sbjct: 121 MLDIVDAIYQMVGNTVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIV 180 Query: 247 NSMQLFENVI 256 ++ L++ ++ Sbjct: 181 QALSLYDGLV 190 >5T7C-A nrPDB Length = 193 Score = 230 bits (587), Expect = 4e-61, Method: Composition-based stats. Identities = 71/180 (39%), Positives = 115/180 (63%) Query: 71 TVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTY 130 + +PE L L+ T+FT ELQ Y+GF +CPTG + D FK IY+ FFP GDA+ + Sbjct: 5 NSKLRPEVLQDLRENTEFTDHELQEWYKGFLKDCPTGHLTVDEFKKIYANFFPYGDASKF 64 Query: 131 AHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAI 190 A +F FD +G+G I F +F++ LS+ RG + +KLKWAF++YD++ +G I++ EML I Sbjct: 65 AEHVFRTFDTNGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRSEMLEI 124 Query: 191 MKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQ 250 +++IY M+ E P + ++ F++MD N DG ++++EF+ + D +I+ +Q Sbjct: 125 VQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVRLLQ 184 >1BJF-A nrPDB Length = 193 Score = 229 bits (583), Expect = 1e-60, Method: Composition-based stats. Identities = 70/184 (38%), Positives = 116/184 (63%) Query: 67 LELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGD 126 + + +PE + L T FT+ E+Q Y+GF +CP+G + + FK IY FFP GD Sbjct: 1 MGKQNSKLRPEVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGD 60 Query: 127 ATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEE 186 A+ +A +F FDA+G+G I F +F++ LS+ RG + +KLKWAF++YD++ +G I+K E Sbjct: 61 ASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAE 120 Query: 187 MLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIM 246 ML I+++IY M+ E P + E+ F++MD N+DG ++++EF+ + D +I+ Sbjct: 121 MLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIV 180 Query: 247 NSMQ 250 +Q Sbjct: 181 RLLQ 184 >2L2E-A nrPDB Length = 190 Score = 228 bits (580), Expect = 2e-60, Method: Composition-based stats. Identities = 76/189 (40%), Positives = 122/189 (64%) Query: 68 ELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDA 127 S + + L L T+F KKELQ Y+GF +CP+G +++ F+ IY QFFP GD Sbjct: 2 GKSQSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDP 61 Query: 128 TTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEM 187 + +A ++FN FDAD NG I F++F+ LS+ RG +++KL WAF LYD++ +G I+ +EM Sbjct: 62 SAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEM 121 Query: 188 LAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMN 247 L I+ +IY M+G ED P + V + F MD+N+DG +T++EF E ++D I++ Sbjct: 122 LRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCEGSKRDPTIVS 181 Query: 248 SMQLFENVI 256 ++ L++ ++ Sbjct: 182 ALSLYDGLV 190 >5M6C-E nrPDB Length = 193 Score = 223 bits (569), Expect = 5e-59, Method: Composition-based stats. Identities = 70/184 (38%), Positives = 118/184 (64%) Query: 67 LELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGD 126 + + +PE L L+ T+F++ ELQ Y+GF +CPTG+++ D FK IY+ FFP GD Sbjct: 1 MGKQNSKLRPEMLQDLRENTEFSELELQEWYKGFLKDCPTGILNVDEFKKIYANFFPYGD 60 Query: 127 ATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEE 186 A+ +A +F FD + +G I F +F++ LS+ RG + +KL WAF++YD++ +G I++EE Sbjct: 61 ASKFAEHVFRNFDTNSDGTIDFREFIIALSVTSRGRLEQKLMWAFSMYDLDGNGYISREE 120 Query: 187 MLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIM 246 ML I+++IY M+ E P + E+ F++MD N DG ++++EF+ + D +I+ Sbjct: 121 MLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFIRGAKSDPSIV 180 Query: 247 NSMQ 250 +Q Sbjct: 181 RLLQ 184 >2JU0-A nrPDB Length = 190 Score = 219 bits (557), Expect = 1e-57, Method: Composition-based stats. Identities = 79/190 (41%), Positives = 116/190 (61%) Query: 67 LELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGD 126 + T + + L L+ T F ++E+Q ++GF +CP+G + + F IY QFFP G Sbjct: 1 MGAKTSKLSKDDLTCLKQSTYFDRREIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGS 60 Query: 127 ATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEE 186 +A+ LF FD D NG IHFE+F+ LS RGT+ EKL WAF LYD+N DG IT +E Sbjct: 61 PEDFANHLFTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDE 120 Query: 187 MLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIM 246 ML I+ S+Y MMG E P V++ F+ MD+N+DG +T+DEF E + D +I+ Sbjct: 121 MLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREGSKVDPSII 180 Query: 247 NSMQLFENVI 256 ++ L++ +I Sbjct: 181 GALNLYDGLI 190 >6EPA-A nrPDB Length = 187 Score = 207 bits (526), Expect = 4e-54, Method: Composition-based stats. Identities = 73/185 (39%), Positives = 115/185 (62%), Gaps = 1/185 (0%) Query: 67 LELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGD 126 + + + + +D+L T FT+KE++ ++GF +CP GL+ E F IY QFFP GD Sbjct: 1 MGKKNSKLKQDTIDRLTTDTYFTEKEIRQWHKGFLKDCPNGLLTEQGFIKIYKQFFPDGD 60 Query: 127 ATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEE 186 + +A +F FD + +GAI FE+F+ LSI RG + EKL WAF LYD++ DG IT+EE Sbjct: 61 PSKFASLVFRVFDENNDGAIEFEEFIRALSITSRGNLDEKLHWAFRLYDVDNDGYITREE 120 Query: 187 MLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIM 246 M I+ +IY M+G+ E+ P + V++ F +MD+N D +T++EF E + D ++ Sbjct: 121 MYNIVDAIYQMVGQQP-QTEDENTPQKRVDKIFDQMDKNHDDRLTLEEFREGSKADPRMV 179 Query: 247 NSMQL 251 ++ L Sbjct: 180 QALSL 184 >2I94-A nrPDB Length = 202 Score = 188 bits (477), Expect = 2e-48, Method: Composition-based stats. Identities = 64/180 (35%), Positives = 107/180 (59%), Gaps = 2/180 (1%) Query: 74 HQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHF 133 E L++LQ TKFT++EL S Y+ F ECP+G + F+ IYS+FFP+ D YA Sbjct: 9 LSKEILEELQLNTKFTEEELSSWYQSFLKECPSGRITRQEFQTIYSKFFPEADPKAYAQH 68 Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS 193 +F +FDA+ +G + F+++V+ L + G ++KL+WAF+LYD++ +G I+K E+L I+ + Sbjct: 69 VFRSFDANSDGTLDFKEYVIALHMTSAGKTNQKLEWAFSLYDVDGNGTISKNEVLEIVTA 128 Query: 194 IYDMMGRHTYPILRED--APLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQL 251 I+ M+ L ED P + E+ + + D +T EF+E ++ I+ +Q Sbjct: 129 IFKMISPEDTKHLPEDENTPEKRAEKIWGFFGKKDDDKLTEKEFIEGTLANKEILRLIQF 188 >2D8N-A nrPDB Length = 207 Score = 185 bits (469), Expect = 2e-47, Method: Composition-based stats. Identities = 61/180 (33%), Positives = 110/180 (61%), Gaps = 2/180 (1%) Query: 74 HQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHF 133 E L++LQ TKF+++EL S Y+ F +CPTG + + F+ IY++FFP D YA Sbjct: 16 LSKEILEELQLNTKFSEEELCSWYQSFLKDCPTGRITQQQFQSIYAKFFPDTDPKAYAQH 75 Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS 193 +F +FD++ +G + F+++V+ L + G ++KL+WAF+LYD++ +G I+K E+L I+ + Sbjct: 76 VFRSFDSNLDGTLDFKEYVIALHMTTAGKTNQKLEWAFSLYDVDGNGTISKNEVLEIVMA 135 Query: 194 IYDMMGRHTYPIL--REDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQL 251 I+ M+ +L E+ P + E+ ++ +N D +T EF+E ++ I+ +Q Sbjct: 136 IFKMITPEDVKLLPDDENTPEKRAEKIWKYFGKNDDDKLTEKEFIEGTLANKEILRLIQF 195 >2R2I-A nrPDB Length = 198 Score = 172 bits (437), Expect = 1e-43, Method: Composition-based stats. Identities = 53/170 (31%), Positives = 89/170 (52%), Gaps = 5/170 (2%) Query: 81 QLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDA 140 +A + + E Y+ F ECP+G + FK + A Y +F FD Sbjct: 4 DSKAVEELSATECHQWYKKFMTECPSGQLTLYEFKQFFGLKNLSPSANKYVEQMFETFDF 63 Query: 141 DGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGR 200 + +G I F ++V LS++L+G V +KL+W F LYD++ +GCI + E+L I+K+I + Sbjct: 64 NKDGYIDFMEYVAALSLVLKGKVDQKLRWYFKLYDVDGNGCIDRGELLNIIKAIRAINRC 123 Query: 201 HTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQ 250 + E F K+D N DG ++++EF+E QKDE +++ + Sbjct: 124 NEAM-----TAEEFTNMVFDKIDINGDGELSLEEFMEGVQKDEVLLDILT 168 >1JBA-A nrPDB Length = 204 Score = 169 bits (427), Expect = 2e-42, Method: Composition-based stats. Identities = 60/186 (32%), Positives = 104/186 (55%), Gaps = 6/186 (3%) Query: 71 TVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTY 130 + E ++ A +LQ Y+ F ECP+G + FK + + +AT Y Sbjct: 2 GQQFSWEEAEENGAVGAADAAQLQEWYKKFLEECPSGTLFMHEFKRFFKVPDNE-EATQY 60 Query: 131 AHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAI 190 +F AFD +G+ I F ++V L+++LRGT+ KLKW F +YD +++GCI ++E+L I Sbjct: 61 VEAMFRAFDTNGDNTIDFLEYVAALNLVLRGTLEHKLKWTFKIYDKDRNGCIDRQELLDI 120 Query: 191 MKSIYDMMGRHTYPILRED-----APLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENI 245 ++SIY + + + E P E V+R F +D N DG ++++EF+E ++D+ + Sbjct: 121 VESIYKLKKACSVEVEAEQQGKLLTPEEVVDRIFLLVDENGDGQLSLNEFVEGARRDKWV 180 Query: 246 MNSMQL 251 M +Q+ Sbjct: 181 MKMLQM 186 >2NA0-A nrPDB Length = 205 Score = 165 bits (418), Expect = 1e-41, Method: Composition-based stats. Identities = 49/168 (29%), Positives = 93/168 (55%), Gaps = 4/168 (2%) Query: 83 QAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADG 142 ++ + + E Y+ F ECP+G + F+ + A+ Y +F FD + Sbjct: 8 KSVEELSSTECHQWYKKFMTECPSGQLTLYEFRQFFGLKNLSPWASQYVEQMFETFDFNK 67 Query: 143 NGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHT 202 +G I F ++ LS++L+G V +KL+W F LYD++ +GCI ++E+L I+++I + Sbjct: 68 DGYIDFMEYEAALSLVLKGKVEQKLRWYFKLYDVDGNGCIDRDELLTIIRAIRAINPCSD 127 Query: 203 YPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQ 250 + E E + F K+D N DG ++++EF+E QKD+ +++++ Sbjct: 128 STMTAE----EFTDTVFSKIDVNGDGELSLEEFMEGVQKDQMLLDTLT 171 >2GGZ-A nrPDB Length = 211 Score = 164 bits (416), Expect = 3e-41, Method: Composition-based stats. Identities = 48/176 (27%), Positives = 87/176 (49%), Gaps = 6/176 (3%) Query: 74 HQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHF 133 H G Q +E YR F E P+GL FK + A + Sbjct: 2 HMGNGKSIAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQ 61 Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS 193 ++N FD + +G + F +F+ ++++++ + +KLKW F LYD + +G I K E+L + + Sbjct: 62 VYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMA 121 Query: 194 IYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSM 249 + + G+ T +P E + F K+D N DG +T++EF+ KD++++ + Sbjct: 122 VQALNGQQTL------SPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIV 171 >1V1G-A nrPDB Length = 222 Score = 150 bits (379), Expect = 5e-37, Method: Composition-based stats. Identities = 55/198 (27%), Positives = 99/198 (50%), Gaps = 11/198 (5%) Query: 59 GSDSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPT----GLVDEDTF 114 G S + + + E + L + T FT +E+++LY FK + GL+ ++ F Sbjct: 2 GCSVSKKKKKNAMRPPGYEDPELLASVTPFTVEEVEALYELFKKLSSSIIDDGLIHKEEF 61 Query: 115 KLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILL-RGTVHEKLKWAFNL 173 + + F + +A +F+ FD NG I F +FV L + VHEK+K+AF L Sbjct: 62 Q--LALFRNRNRRNLFADRIFDVFDVKRNGVIEFGEFVRSLGVFHPSAPVHEKVKFAFKL 119 Query: 174 YDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTID 233 YD+ + G I +EE+ ++ ++ + +L ED V++ F + DR DG + ID Sbjct: 120 YDLRQTGFIEREELKEMVVALL----HESELVLSEDMIEVMVDKAFVQADRKNDGKIDID 175 Query: 234 EFLETCQKDENIMNSMQL 251 E+ + + +++ +M L Sbjct: 176 EWKDFVSLNPSLIKNMTL 193 >5YPX-A nrPDB Length = 223 Score = 147 bits (371), Expect = 4e-36, Method: Composition-based stats. Identities = 55/194 (28%), Positives = 96/194 (49%), Gaps = 10/194 (5%) Query: 56 APQGSDSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFK 115 P+GS S +L+ E L + Q FTK E++SL +KN +D + F+ Sbjct: 15 VPRGSHMSKKNQKLA------EELYKTSCQKHFTKTEVESLIICYKNLLEGLKMDRNLFR 68 Query: 116 LIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYD 175 I Q F + +F AFD D + I ++V GLS+ LRGT+ EK+++ F ++D Sbjct: 69 DILHQKFNMTEDLLM-DRVFRAFDKDSDSYISLTEWVEGLSVFLRGTLDEKMEYTFTVFD 127 Query: 176 INKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEF 235 +N DG I++EEM ++K+ P ++ + VE +KMD + D ++ +F Sbjct: 128 LNGDGYISREEMFQMLKTCLVKQPTEEDP---DEGIKDLVEIALKKMDHDHDSRLSKKDF 184 Query: 236 LETCQKDENIMNSM 249 + + ++ + Sbjct: 185 KDAVLIEPLLLEAF 198 >2ZFD-A nrPDB Length = 226 Score = 145 bits (367), Expect = 1e-35, Method: Composition-based stats. Identities = 41/177 (23%), Positives = 87/177 (49%), Gaps = 11/177 (6%) Query: 80 DQLQAQTKFTKKELQSLYRGFKNECP----TGLVDEDTFKLIYSQFFPQGDATTYAHFLF 135 + L T F+ E+++LY FK GL++++ F+ + F + +A +F Sbjct: 34 ELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFADRVF 91 Query: 136 NAFDADGNGAIHFEDFVVGLSILL-RGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSI 194 + FD NG + FE+F LS+ + +K+ ++F LYD+ + G I ++E+ ++ + Sbjct: 92 DLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVAT 151 Query: 195 YDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQL 251 G + + ED +++ F++ D DG + +E+ + +++ +M L Sbjct: 152 LAESGMNLKDTVIEDI----IDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTL 204 >4IL1-A nrPDB Length = 823 Score = 143 bits (361), Expect = 7e-35, Method: Composition-based stats. Identities = 40/166 (24%), Positives = 78/166 (46%), Gaps = 15/166 (9%) Query: 77 EGLDQLQAQTKFTKKELQSLYRGFKNEC--PTGLVDEDTFKLIYSQFFPQGDATTYAHFL 134 E L+ + F E++ L + FK +G + + F P+ + Sbjct: 161 EASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-----LPELQQNPLVQRV 215 Query: 135 FNAFDADGNGAIHFEDFVVGLSILL-RGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS 193 + FD DGNG + F++F+ G+S +G +KL++AF +YD++KDG I+ E+ ++K Sbjct: 216 IDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKM 275 Query: 194 IYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETC 239 + L++ + V++ D++ DG ++ +EF Sbjct: 276 M-------VGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVV 314 Score = 103 bits (256), Expect = 9e-23, Method: Composition-based stats. Identities = 30/142 (21%), Positives = 53/142 (37%), Gaps = 49/142 (34%) Query: 135 FNAFDA------------------------------------DGNGAIHFEDFVVGLSIL 158 F+ FD DGNG I F +F+ ++ Sbjct: 17 FSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARK 76 Query: 159 LRGT-VHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVER 217 ++ T E+++ AF ++D + +G I+ E+ RH L E E V+ Sbjct: 77 MKDTDSEEEIREAFRVFDKDGNGYISAAEL------------RHVMTNLGEKLTDEEVDE 124 Query: 218 FFQKMDRNQDGVVTIDEFLETC 239 ++ D + DG V +EF++ Sbjct: 125 MIREADIDGDGQVNYEEFVQMM 146 Score = 87.1 bits (214), Expect = 7e-18, Method: Composition-based stats. Identities = 34/254 (13%), Positives = 73/254 (28%), Gaps = 89/254 (35%) Query: 88 FTKKELQSLYRGF--KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGA 145 T++++ F ++ G + + + N DADGNG Sbjct: 5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQD-MINEVDADGNGT 63 Query: 146 IHFEDFVVGLSILLRGT-VHEKLKWAFNLYDI---------------------------- 176 I F +F+ ++ ++ T E+++ AF ++D Sbjct: 64 IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVD 123 Query: 177 --------NKDGCITKEEMLAIMKSIYDM------------------------------- 197 + DG + EE + +M + Sbjct: 124 EMIREADIDGDGQVNYEEFVQMMTAKGGGGGGGGGGNEASYPLEMCSHFDADEIKRLGKR 183 Query: 198 -----------MGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQ------ 240 + + L E V+R D + +G V EF+E Sbjct: 184 FKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKG 243 Query: 241 -KDENIMNSMQLFE 253 K++ + + ++++ Sbjct: 244 DKEQKLRFAFRIYD 257 >1UHN-A nrPDB Length = 189 Score = 141 bits (356), Expect = 2e-34, Method: Composition-based stats. Identities = 41/177 (23%), Positives = 87/177 (49%), Gaps = 11/177 (6%) Query: 80 DQLQAQTKFTKKELQSLYRGFKNECP----TGLVDEDTFKLIYSQFFPQGDATTYAHFLF 135 + L T F+ E+++LY FK GL++++ F+ + F + +A +F Sbjct: 3 ELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQ--LALFKTNKKESLFADRVF 60 Query: 136 NAFDADGNGAIHFEDFVVGLSILL-RGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSI 194 + FD NG + FE+F LS+ + +K+ ++F LYD+ + G I ++E+ ++ + Sbjct: 61 DLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVAT 120 Query: 195 YDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQL 251 G + + ED +++ F++ D DG + +E+ + +++ +M L Sbjct: 121 LAESGMNLKDTVIEDI----IDKTFEEADTKHDGKIDKEEWRSLVLRHPSLLKNMTL 173 >3NCG-A nrPDB Length = 486 Score = 138 bits (347), Expect = 3e-33, Method: Composition-based stats. Identities = 48/226 (21%), Positives = 85/226 (37%), Gaps = 37/226 (16%) Query: 39 RQALMRCCLIKWI--LSSAAPQGSDSSDSELELSTVRH--------QPEGLDQLQAQTKF 88 R +C WI SS P SD E ++ +R Q L T Sbjct: 268 RITATQCLEHPWIQKYSSETPTISDLPSLESAMTNIRQFQAEKKLAQAALLYMASKLTTL 327 Query: 89 TK-KELQSLYRGFKNECPTGLVDEDTFKLIYSQF----------FPQGDATTYAHFL--- 134 + K+L ++R G++D D Y +F Q + +T + Sbjct: 328 DETKQLTEIFRKLDTN-NDGMLDRDELVRGYHEFMRLKGVDSNSLIQNEGSTIEDQIDSL 386 Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSI 194 D DG+G+I + +F+ E+++ AF ++D + G I+ +E+ + Sbjct: 387 MPLLDMDGSGSIEYSEFIASAIDRTILLSRERMERAFKMFDKDGSGKISTKELFKLF--- 443 Query: 195 YDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQ 240 +E +E +++D N+DG V +EF+E Q Sbjct: 444 ---------SQADSSIQMEELESIIEQVDNNKDGEVDFNEFVEMLQ 480 Score = 46.2 bits (108), Expect = 1e-05, Method: Composition-based stats. Identities = 15/102 (14%), Positives = 38/102 (37%), Gaps = 3/102 (2%) Query: 60 SDSSDSELELSTVRHQPEGLDQLQAQTKF-TKKELQSLYRGFKNECPTGLVDEDTFKLIY 118 S +++ S E + +T +++ ++ ++ F + +G + ++ Sbjct: 385 SLMPLLDMDGSGSIEYSEFIASAIDRTILLSRERMERAFKMFDKD-GSGKISTKELFKLF 443 Query: 119 SQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLR 160 SQ + D + +G + F +FV L +R Sbjct: 444 SQADSSIQMEEL-ESIIEQVDNNKDGEVDFNEFVEMLQNFVR 484 >3U0K-A nrPDB Length = 442 Score = 136 bits (342), Expect = 9e-33, Method: Composition-based stats. Identities = 32/155 (20%), Positives = 65/155 (41%), Gaps = 16/155 (10%) Query: 88 FTKKELQSLYRGF--KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGA 145 T++++ F ++ G + + + N DADG+G Sbjct: 298 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQD-MINEVDADGDGT 356 Query: 146 IHFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYP 204 I F +F++ ++ ++ T E+++ AF ++D + +G I+ E+ RH Sbjct: 357 IDFPEFLIMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL------------RHVMT 404 Query: 205 ILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETC 239 L E E V+ ++ D + DG V +EF++ Sbjct: 405 NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 439 Score = 57.4 bits (137), Expect = 7e-09, Method: Composition-based stats. Identities = 25/105 (23%), Positives = 44/105 (41%), Gaps = 1/105 (0%) Query: 89 TKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHF 148 T+ ELQ + + G +D F ++ ++ D+ F FD DGNG I Sbjct: 338 TEAELQDMINE-VDADGDGTIDFPEFLIMMARKMKDTDSEEEIREAFRVFDKDGNGYISA 396 Query: 149 EDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS 193 + ++ L E++ DI+ DG + EE + +M + Sbjct: 397 AELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 441 >2LM5-A nrPDB Length = 214 Score = 136 bits (342), Expect = 9e-33, Method: Composition-based stats. Identities = 43/200 (21%), Positives = 83/200 (41%), Gaps = 14/200 (7%) Query: 61 DSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECP-------TGLVDEDT 113 D D + S R E L + Q T TK+E+ +R F P + L + Sbjct: 18 DDDDKHMGGSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVP 77 Query: 114 FKLIYSQFFPQGDATTYAHFLFNAFDA-DGNGAIHFEDFVVGLSILL-RGTVHEKLKWAF 171 F+ I S P+ A + + F ++ FEDF+ LS+ T K +AF Sbjct: 78 FEQILS--LPELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAF 135 Query: 172 NLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVT 231 ++D + DG + +E++ ++ + G L + ++ ++ D ++DG + Sbjct: 136 RIFDFDDDGTLNREDLSRLVNCL---TGEGEDTRLSASEMKQLIDNILEESDIDRDGTIN 192 Query: 232 IDEFLETCQKDENIMNSMQL 251 + EF + + +S ++ Sbjct: 193 LSEFQHVISRSPDFASSFKI 212 >3EK4-A nrPDB Length = 451 Score = 136 bits (342), Expect = 1e-32, Method: Composition-based stats. Identities = 33/162 (20%), Positives = 67/162 (41%), Gaps = 16/162 (9%) Query: 81 QLQAQTKFTKKELQSLYRGF--KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAF 138 + + + T++++ F ++ G + + + N Sbjct: 300 EYNTRDQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQD-MINEV 358 Query: 139 DADGNGAIHFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDM 197 DADGNG I F +F+ ++ ++ T E+++ AF ++D + +G I+ E+ Sbjct: 359 DADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL---------- 408 Query: 198 MGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETC 239 RH L E E V+ ++ D + DG V +EF++ Sbjct: 409 --RHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 448 Score = 57.0 bits (136), Expect = 7e-09, Method: Composition-based stats. Identities = 25/105 (23%), Positives = 43/105 (40%), Gaps = 1/105 (0%) Query: 89 TKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHF 148 T+ ELQ + + G +D F + ++ D+ F FD DGNG I Sbjct: 347 TEAELQDMINE-VDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISA 405 Query: 149 EDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS 193 + ++ L E++ DI+ DG + EE + +M + Sbjct: 406 AELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 450 >4OY4-A nrPDB Length = 415 Score = 135 bits (341), Expect = 1e-32, Method: Composition-based stats. Identities = 32/155 (20%), Positives = 64/155 (41%), Gaps = 16/155 (10%) Query: 88 FTKKELQSLYRGF--KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGA 145 T++++ F ++ G + + + N DADG+G Sbjct: 12 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQD-MINEVDADGDGT 70 Query: 146 IHFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYP 204 I F +F+ ++ ++ T E+++ AF ++D + +G I+ E+ RH Sbjct: 71 IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL------------RHVMT 118 Query: 205 ILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETC 239 L E E V+ ++ D + DG V +EF++ Sbjct: 119 NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 153 Score = 57.4 bits (137), Expect = 6e-09, Method: Composition-based stats. Identities = 25/105 (23%), Positives = 43/105 (40%), Gaps = 1/105 (0%) Query: 89 TKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHF 148 T+ ELQ + + G +D F + ++ D+ F FD DGNG I Sbjct: 52 TEAELQDMINE-VDADGDGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISA 110 Query: 149 EDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS 193 + ++ L E++ DI+ DG + EE + +M + Sbjct: 111 AELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 155 Score = 49.7 bits (117), Expect = 1e-06, Method: Composition-based stats. Identities = 12/72 (16%), Positives = 32/72 (44%), Gaps = 2/72 (2%) Query: 89 TKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHF 148 +++E++ +R F + G + + + + + + D DG+G +++ Sbjct: 89 SEEEIREAFRVFDKD-GNGYISAAELRHVMTNLGEKLTDEE-VDEMIREADIDGDGQVNY 146 Query: 149 EDFVVGLSILLR 160 E+FV ++ L Sbjct: 147 EEFVQMMTAKLE 158 >4ORC-B nrPDB Length = 170 Score = 134 bits (338), Expect = 3e-32, Method: Composition-based stats. Identities = 40/166 (24%), Positives = 78/166 (46%), Gaps = 15/166 (9%) Query: 77 EGLDQLQAQTKFTKKELQSLYRGFKNEC--PTGLVDEDTFKLIYSQFFPQGDATTYAHFL 134 E L+ + F E++ L + FK +G + + F P+ + Sbjct: 4 EASYPLEMCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMS-----LPELQQNPLVQRV 58 Query: 135 FNAFDADGNGAIHFEDFVVGLSILL-RGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS 193 + FD DGNG + F++F+ G+S +G +KL++AF +YD++KDG I+ E+ ++K Sbjct: 59 IDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKM 118 Query: 194 IYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETC 239 + L++ + V++ D++ DG ++ +EF Sbjct: 119 M-------VGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVV 157 Score = 41.6 bits (96), Expect = 4e-04, Method: Composition-based stats. Identities = 18/109 (16%), Positives = 39/109 (35%), Gaps = 24/109 (22%) Query: 152 VVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAP 211 + S + ++L F D++ G ++ EE + L E Sbjct: 9 LEMCSHFDADEI-KRLGKRFKKLDLDNSGSLSVEE----------------FMSLPELQQ 51 Query: 212 LEHVERFFQKMDRNQDGVVTIDEFLETCQ-------KDENIMNSMQLFE 253 V+R D + +G V EF+E K++ + + ++++ Sbjct: 52 NPLVQRVIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYD 100 >2E6W-A nrPDB Length = 100 Score = 131 bits (329), Expect = 4e-31, Method: Composition-based stats. Identities = 90/96 (93%), Positives = 93/96 (96%) Query: 161 GTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQ 220 GTVHEKLKWAFNLYDINKDG ITKEEMLAIMKSIYDMMGRHTYPILREDAP EHVERFF+ Sbjct: 5 GTVHEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFFE 64 Query: 221 KMDRNQDGVVTIDEFLETCQKDENIMNSMQLFENVI 256 KMDRNQDGVVTI+EFLE CQKDENIM+SMQLFENVI Sbjct: 65 KMDRNQDGVVTIEEFLEACQKDENIMSSMQLFENVI 100 >5B8I-B nrPDB Length = 171 Score = 130 bits (328), Expect = 4e-31, Method: Composition-based stats. Identities = 45/181 (24%), Positives = 88/181 (48%), Gaps = 16/181 (8%) Query: 74 HQPEGLDQLQAQTKFTKKELQSLYRGFKNEC--PTGLVDEDTFKLIYSQFFPQGDATTYA 131 + L+ + + + F +E+ L++ F +G ++ D F PQ + + Sbjct: 1 MSSQVLNDIVSGSNFDHEEVDRLWKRFMKLDRDKSGTIERDEFLS-----LPQVSSNPLS 55 Query: 132 HFLFNAFDADGNGAIHFEDFVVGLSILL-RGTVHEKLKWAFNLYDINKDGCITKEEMLAI 190 + FD DG G + F++FV GLS +G EKL++AF +YDI++DG I+ E+ + Sbjct: 56 TRMIAIFDEDGGGDVDFQEFVSGLSAFSSKGNKEEKLRFAFKVYDIDRDGFISNGELFIV 115 Query: 191 MKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQ 250 +K + L++ + V++ + D + DG ++ +EF + + ++ SM Sbjct: 116 LKMM-------VGSNLKDMQLQQIVDKTIMEADLDGDGRISFEEFTRMVE-NTDVSMSMT 167 Query: 251 L 251 L Sbjct: 168 L 168 >5UKG-A nrPDB Length = 419 Score = 125 bits (315), Expect = 1e-29, Method: Composition-based stats. Identities = 30/160 (18%), Positives = 61/160 (38%), Gaps = 16/160 (10%) Query: 83 QAQTKFTKKELQSLYRGF--KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDA 140 + + T++++ F ++ G + + + N DA Sbjct: 270 ASNGQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQD-MINEVDA 328 Query: 141 DGNGAIHFEDFVVGLSILLR-GTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMG 199 DG+G F +F+ ++ + E+++ AF ++D + +G I E+ Sbjct: 329 DGDGTFDFPEFLTMMARKMSYRVTEEEIREAFRVFDKDGNGYIGAAEL------------ 376 Query: 200 RHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETC 239 RH L E E V+ + D + DG V +EF++ Sbjct: 377 RHVMTDLGEKLTDEEVDEMIRVADIDGDGQVNYEEFVQMM 416 Score = 53.5 bits (127), Expect = 9e-08, Method: Composition-based stats. Identities = 24/105 (22%), Positives = 41/105 (39%), Gaps = 1/105 (0%) Query: 89 TKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHF 148 T+ ELQ + + G D F + ++ F FD DGNG I Sbjct: 315 TEAELQDMINE-VDADGDGTFDFPEFLTMMARKMSYRVTEEEIREAFRVFDKDGNGYIGA 373 Query: 149 EDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS 193 + ++ L E++ + DI+ DG + EE + +M + Sbjct: 374 AELRHVMTDLGEKLTDEEVDEMIRVADIDGDGQVNYEEFVQMMTA 418 >3WFN-B nrPDB Length = 182 Score = 125 bits (314), Expect = 2e-29, Method: Composition-based stats. Identities = 33/155 (21%), Positives = 64/155 (41%), Gaps = 16/155 (10%) Query: 88 FTKKELQSLYRGF--KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGA 145 T++++ F ++ G + + + N DADGNG Sbjct: 11 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQD-MINEVDADGNGT 69 Query: 146 IHFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYP 204 I F +F+ ++ ++ T E+++ AF ++D + +G I+ E+ RH Sbjct: 70 IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL------------RHVMT 117 Query: 205 ILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETC 239 L E E V+ ++ D + DG V +EF++ Sbjct: 118 NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 152 Score = 55.1 bits (131), Expect = 3e-08, Method: Composition-based stats. Identities = 29/129 (22%), Positives = 51/129 (39%), Gaps = 1/129 (0%) Query: 89 TKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHF 148 T+ ELQ + + G +D F + ++ D+ F FD DGNG I Sbjct: 51 TEAELQDMINE-VDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISA 109 Query: 149 EDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILRE 208 + ++ L E++ DI+ DG + EE + +M + G ++ + Sbjct: 110 AELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAKGGGGGEEVSAVVLQ 169 Query: 209 DAPLEHVER 217 A H+ R Sbjct: 170 RAYRGHLAR 178 >4I2Y-A nrPDB Length = 421 Score = 125 bits (313), Expect = 2e-29, Method: Composition-based stats. Identities = 31/155 (20%), Positives = 60/155 (38%), Gaps = 16/155 (10%) Query: 88 FTKKELQSLYRGF--KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGA 145 T++++ F ++ G + + + N DADG+G Sbjct: 277 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQD-MINEVDADGDGT 335 Query: 146 IHFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYP 204 F +F+ ++ + T E+++ AF ++D + +G I E+ RH Sbjct: 336 FDFPEFLTMMARKMNDTDSEEEIREAFRVFDKDGNGYIGAAEL------------RHVMT 383 Query: 205 ILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETC 239 L E E V+ + D + DG V +EF++ Sbjct: 384 DLGEKLTDEEVDEMIRVADIDGDGQVNYEEFVQMM 418 Score = 56.6 bits (135), Expect = 1e-08, Method: Composition-based stats. Identities = 25/105 (23%), Positives = 43/105 (40%), Gaps = 1/105 (0%) Query: 89 TKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHF 148 T+ ELQ + + G D F + ++ D+ F FD DGNG I Sbjct: 317 TEAELQDMINE-VDADGDGTFDFPEFLTMMARKMNDTDSEEEIREAFRVFDKDGNGYIGA 375 Query: 149 EDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS 193 + ++ L E++ + DI+ DG + EE + +M + Sbjct: 376 AELRHVMTDLGEKLTDEEVDEMIRVADIDGDGQVNYEEFVQMMTA 420 >2N6A-A nrPDB Length = 173 Score = 123 bits (309), Expect = 7e-29, Method: Composition-based stats. Identities = 33/154 (21%), Positives = 64/154 (41%), Gaps = 16/154 (10%) Query: 89 TKKELQSLYRGF--KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAI 146 T++++ F ++ G + + + N DADGNG I Sbjct: 7 TEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQD-MINEVDADGNGTI 65 Query: 147 HFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPI 205 F +F+ ++ ++ T E+++ AF ++D + +G I+ E+ RH Sbjct: 66 DFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL------------RHVMTN 113 Query: 206 LREDAPLEHVERFFQKMDRNQDGVVTIDEFLETC 239 L E E V+ ++ D + DG V +EF++ Sbjct: 114 LGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 147 Score = 61.2 bits (147), Expect = 4e-10, Method: Composition-based stats. Identities = 21/95 (22%), Positives = 43/95 (45%), Gaps = 19/95 (20%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRN 225 + K AF+L+D + DG IT +E+ +M+S L ++ ++ ++D + Sbjct: 13 EFKEAFSLFDKDGDGTITTKELGTVMRS------------LGQNPTEAELQDMINEVDAD 60 Query: 226 QDGVVTIDEFLETCQKD-------ENIMNSMQLFE 253 +G + EFL + E I + ++F+ Sbjct: 61 GNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFD 95 Score = 54.3 bits (129), Expect = 5e-08, Method: Composition-based stats. Identities = 27/117 (23%), Positives = 44/117 (37%), Gaps = 1/117 (0%) Query: 89 TKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHF 148 T+ ELQ + + G +D F + ++ D+ F FD DGNG I Sbjct: 46 TEAELQDMINE-VDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISA 104 Query: 149 EDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPI 205 + ++ L E++ DI+ DG + EE + +M G I Sbjct: 105 AELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTGASTAAGSGWRKI 161 >6O20-F nrPDB Length = 169 Score = 122 bits (305), Expect = 2e-28, Method: Composition-based stats. Identities = 33/155 (21%), Positives = 64/155 (41%), Gaps = 16/155 (10%) Query: 88 FTKKELQSLYRGF--KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGA 145 T++++ F ++ G + + + N DADGNG Sbjct: 25 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQD-MINEVDADGNGT 83 Query: 146 IHFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYP 204 I F +F+ ++ ++ T E+++ AF ++D + +G I+ E+ RH Sbjct: 84 IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL------------RHVMT 131 Query: 205 ILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETC 239 L E E V+ ++ D + DG V +EF++ Sbjct: 132 NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 166 >1DGU-A nrPDB Length = 183 Score = 121 bits (304), Expect = 2e-28, Method: Composition-based stats. Identities = 39/186 (20%), Positives = 78/186 (41%), Gaps = 14/186 (7%) Query: 75 QPEGLDQLQAQTKFTKKELQSLYRGFKNECP-------TGLVDEDTFKLIYSQFFPQGDA 127 E L + Q T TK+E+ +R F P + L + F+ I S P+ A Sbjct: 1 SKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILS--LPELKA 58 Query: 128 TTYAHFLFNAFDA-DGNGAIHFEDFVVGLSILL-RGTVHEKLKWAFNLYDINKDGCITKE 185 + + F ++ FEDF+ LS+ T K +AF ++D + DG + +E Sbjct: 59 NPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNRE 118 Query: 186 EMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENI 245 ++ ++ + G L + ++ ++ D ++DG + + EF + + Sbjct: 119 DLSRLVNCL---TGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRSPDF 175 Query: 246 MNSMQL 251 +S ++ Sbjct: 176 ASSFKI 181 >2F2P-A nrPDB Length = 179 Score = 121 bits (303), Expect = 3e-28, Method: Composition-based stats. Identities = 33/155 (21%), Positives = 64/155 (41%), Gaps = 16/155 (10%) Query: 88 FTKKELQSLYRGF--KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGA 145 T++++ F ++ G + + + N DADGNG Sbjct: 5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQD-MINEVDADGNGT 63 Query: 146 IHFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYP 204 I F +F+ ++ ++ T E+++ AF ++D + +G I+ E+ RH Sbjct: 64 IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL------------RHVMT 111 Query: 205 ILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETC 239 L E E V+ ++ D + DG V +EF++ Sbjct: 112 NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146 Score = 52.0 bits (123), Expect = 2e-07, Method: Composition-based stats. Identities = 25/105 (23%), Positives = 43/105 (40%), Gaps = 1/105 (0%) Query: 89 TKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHF 148 T+ ELQ + + G +D F + ++ D+ F FD DGNG I Sbjct: 45 TEAELQDMINE-VDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISA 103 Query: 149 EDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS 193 + ++ L E++ DI+ DG + EE + +M + Sbjct: 104 AELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 148 Score = 43.5 bits (101), Expect = 9e-05, Method: Composition-based stats. Identities = 11/70 (15%), Positives = 31/70 (44%), Gaps = 2/70 (2%) Query: 89 TKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHF 148 +++E++ +R F + G + + + + + + D DG+G +++ Sbjct: 82 SEEEIREAFRVFDKD-GNGYISAAELRHVMTNLGEKLTDEE-VDEMIREADIDGDGQVNY 139 Query: 149 EDFVVGLSIL 158 E+FV ++ Sbjct: 140 EEFVQMMTAK 149 >4E53-A nrPDB Length = 185 Score = 119 bits (299), Expect = 1e-27, Method: Composition-based stats. Identities = 33/155 (21%), Positives = 64/155 (41%), Gaps = 16/155 (10%) Query: 88 FTKKELQSLYRGF--KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGA 145 T++++ F ++ G + + + N DADGNG Sbjct: 12 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQD-MINEVDADGNGT 70 Query: 146 IHFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYP 204 I F +F+ ++ ++ T E+++ AF ++D + +G I+ E+ RH Sbjct: 71 IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL------------RHVMT 118 Query: 205 ILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETC 239 L E E V+ ++ D + DG V +EF++ Sbjct: 119 NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 153 Score = 42.4 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 17/101 (16%), Positives = 41/101 (40%), Gaps = 10/101 (9%) Query: 89 TKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHF 148 +++E++ +R F + G + + + + + + D DG+G +++ Sbjct: 89 SEEEIREAFRVFDKD-GNGYISAAELRHVMTNLGEKLTDEE-VDEMIREADIDGDGQVNY 146 Query: 149 EDFVVGLSILLRGTVHEKLKWA-FNLYDINKDGCITKEEML 188 E+FV ++ G A F G IT++++ Sbjct: 147 EEFVQMMTAKGGGGGAATKIQASFR-------GHITRKKLK 180 >6HCS-A nrPDB Length = 167 Score = 119 bits (299), Expect = 1e-27, Method: Composition-based stats. Identities = 35/170 (20%), Positives = 67/170 (39%), Gaps = 16/170 (9%) Query: 88 FTKKELQSLYRGF--KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGA 145 T++++ F ++ G + + + N DADGNG Sbjct: 5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQD-MINEVDADGNGT 63 Query: 146 IHFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYP 204 I F +F+ ++ ++ T E+++ AF ++D + +G I+ E+ RH Sbjct: 64 IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL------------RHFMT 111 Query: 205 ILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQLFEN 254 L E E V+ ++ D + DG V +EF++ LF+ Sbjct: 112 NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAKLEGTGLEVLFQG 161 >5I0I-E nrPDB Length = 145 Score = 118 bits (295), Expect = 3e-27, Method: Composition-based stats. Identities = 33/155 (21%), Positives = 64/155 (41%), Gaps = 16/155 (10%) Query: 88 FTKKELQSLYRGFK--NECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGA 145 T++++ F ++ G + + + N DADGNG Sbjct: 3 LTEEQIAEFKEAFSLADKDGDGTITTKELGTVMRSLGQNPTEAELQD-MINEVDADGNGT 61 Query: 146 IHFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYP 204 I F +F+ ++ ++ T E+++ AF ++D + +G I+ E+ RH Sbjct: 62 IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL------------RHVMT 109 Query: 205 ILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETC 239 L E E V+ ++ D + DG V +EF++ Sbjct: 110 NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 144 Score = 55.5 bits (132), Expect = 2e-08, Method: Composition-based stats. Identities = 21/95 (22%), Positives = 42/95 (44%), Gaps = 19/95 (20%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRN 225 + K AF+L D + DG IT +E+ +M+S L ++ ++ ++D + Sbjct: 10 EFKEAFSLADKDGDGTITTKELGTVMRS------------LGQNPTEAELQDMINEVDAD 57 Query: 226 QDGVVTIDEFLETCQKD-------ENIMNSMQLFE 253 +G + EFL + E I + ++F+ Sbjct: 58 GNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFD 92 Score = 42.0 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 11/68 (16%), Positives = 31/68 (45%), Gaps = 2/68 (2%) Query: 89 TKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHF 148 +++E++ +R F + G + + + + + + D DG+G +++ Sbjct: 80 SEEEIREAFRVFDKD-GNGYISAAELRHVMTNLGEKLTDEE-VDEMIREADIDGDGQVNY 137 Query: 149 EDFVVGLS 156 E+FV ++ Sbjct: 138 EEFVQMMT 145 >2E30-A nrPDB Length = 195 Score = 113 bits (282), Expect = 1e-25, Method: Composition-based stats. Identities = 37/190 (19%), Positives = 84/190 (44%), Gaps = 30/190 (15%) Query: 70 STVRHQPEGLDQLQAQTKFTKKELQSLYRGF--KNECPTGLVDEDTFKLIYSQFFPQGDA 127 ++ + E L++++ +T F+ ++ LY F ++ G + + F+ I P+ Sbjct: 5 ASTLLRDEELEEIKKETGFSHSQITRLYSRFTSLDKGENGTLSREDFQRI-----PELAI 59 Query: 128 TTYAHFLFNAFDADGNGAIHFEDFVVGLSIL----------------LRGTVHEKLKWAF 171 + NAF +G ++F F+ L+ + KL +AF Sbjct: 60 NPLGDRIINAFFPEGEDQVNFRGFMRTLAHFRPIEDNEKSKDVNGPEPLNSRSNKLHFAF 119 Query: 172 NLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVT 231 LYD++KD I+++E+L +++ + + ++ +R Q+ D++ D ++ Sbjct: 120 RLYDLDKDEKISRDELLQVLRMM-------VGVNISDEQLGSIADRTIQEADQDGDSAIS 172 Query: 232 IDEFLETCQK 241 EF++ +K Sbjct: 173 FTEFVKVLEK 182 >5A2H-A nrPDB Length = 149 Score = 113 bits (282), Expect = 1e-25, Method: Composition-based stats. Identities = 34/150 (22%), Positives = 62/150 (41%), Gaps = 15/150 (10%) Query: 91 KELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFED 150 E + + F + G + + + N DADGNG I F + Sbjct: 11 SEFKEAFSLFDKD-GDGCITTKELGTVMRSLGQNPTEAELQD-MINEVDADGNGTIDFPE 68 Query: 151 FVVGLSILLRGT-VHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILRED 209 F+ ++ ++ T E+LK AF ++D +++G I+ E+ RH L E Sbjct: 69 FLNLMARKMKDTDSEEELKEAFRVFDKDQNGFISAAEL------------RHVMTNLGEK 116 Query: 210 APLEHVERFFQKMDRNQDGVVTIDEFLETC 239 E V+ ++ D + DG + +EF++ Sbjct: 117 LTDEEVDEMIREADVDGDGQINYEEFVKVM 146 Score = 57.4 bits (137), Expect = 6e-09, Method: Composition-based stats. Identities = 22/106 (20%), Positives = 47/106 (44%), Gaps = 19/106 (17%) Query: 155 LSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEH 214 ++ L + K AF+L+D + DGCIT +E+ +M+S L ++ Sbjct: 1 MADQLTDDQISEFKEAFSLFDKDGDGCITTKELGTVMRS------------LGQNPTEAE 48 Query: 215 VERFFQKMDRNQDGVVTIDEFLETCQKD-------ENIMNSMQLFE 253 ++ ++D + +G + EFL + E + + ++F+ Sbjct: 49 LQDMINEVDADGNGTIDFPEFLNLMARKMKDTDSEEELKEAFRVFD 94 Score = 48.5 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 20/92 (21%), Positives = 36/92 (39%) Query: 102 NECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRG 161 + G +D F + ++ D+ F FD D NG I + ++ L Sbjct: 57 DADGNGTIDFPEFLNLMARKMKDTDSEEELKEAFRVFDKDQNGFISAAELRHVMTNLGEK 116 Query: 162 TVHEKLKWAFNLYDINKDGCITKEEMLAIMKS 193 E++ D++ DG I EE + +M + Sbjct: 117 LTDEEVDEMIREADVDGDGQINYEEFVKVMMA 148 >1CLM-A nrPDB Length = 148 Score = 112 bits (281), Expect = 1e-25, Method: Composition-based stats. Identities = 31/156 (19%), Positives = 62/156 (39%), Gaps = 16/156 (10%) Query: 87 KFTKKELQSLYRGF--KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNG 144 + T++++ F ++ G + + + N DADGNG Sbjct: 3 ELTEEQIAEFKEAFALFDKDGDGTITTKELGTVMRSLGQNPTEAELQD-MINEVDADGNG 61 Query: 145 AIHFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTY 203 I F +F+ ++ ++ E+L AF ++D + +G I+ E+ RH Sbjct: 62 TIDFPEFLSLMARKMKEQDSEEELIEAFKVFDRDGNGLISAAEL------------RHVM 109 Query: 204 PILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETC 239 L E + V+ ++ D + DG + +EF+ Sbjct: 110 TNLGEKLTDDEVDEMIREADIDGDGHINYEEFVRMM 145 Score = 58.9 bits (141), Expect = 2e-09, Method: Composition-based stats. Identities = 20/95 (21%), Positives = 43/95 (45%), Gaps = 19/95 (20%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRN 225 + K AF L+D + DG IT +E+ +M+S L ++ ++ ++D + Sbjct: 11 EFKEAFALFDKDGDGTITTKELGTVMRS------------LGQNPTEAELQDMINEVDAD 58 Query: 226 QDGVVTIDEFLETCQKD-------ENIMNSMQLFE 253 +G + EFL + E ++ + ++F+ Sbjct: 59 GNGTIDFPEFLSLMARKMKEQDSEEELIEAFKVFD 93 >1GGZ-A nrPDB Length = 148 Score = 109 bits (272), Expect = 1e-24, Method: Composition-based stats. Identities = 29/155 (18%), Positives = 61/155 (39%), Gaps = 16/155 (10%) Query: 88 FTKKELQSLYRGF--KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGA 145 T++++ F ++ G + + + + D DGNG Sbjct: 4 LTEEQVTEFKEAFSLFDKDGDGCITTRELGTVMRSLGQNPTEAELRD-MMSEIDRDGNGT 62 Query: 146 IHFEDFVVGLSILLRGTV-HEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYP 204 + F +F+ ++ ++ T E+++ AF ++D + +G ++ E+ RH Sbjct: 63 VDFPEFLGMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAAEL------------RHVMT 110 Query: 205 ILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETC 239 L E E V+ + D + DG V +EF+ Sbjct: 111 RLGEKLSDEEVDEMIRAADTDGDGQVNYEEFVRVL 145 Score = 57.8 bits (138), Expect = 5e-09, Method: Composition-based stats. Identities = 24/95 (25%), Positives = 43/95 (45%), Gaps = 19/95 (20%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRN 225 + K AF+L+D + DGCIT E+ +M+S L ++ + ++DR+ Sbjct: 11 EFKEAFSLFDKDGDGCITTRELGTVMRS------------LGQNPTEAELRDMMSEIDRD 58 Query: 226 QDGVVTIDEFLETCQKD-------ENIMNSMQLFE 253 +G V EFL + E I + ++F+ Sbjct: 59 GNGTVDFPEFLGMMARKMKDTDNEEEIREAFRVFD 93 >2L1W-A nrPDB Length = 149 Score = 102 bits (255), Expect = 1e-22, Method: Composition-based stats. Identities = 34/155 (21%), Positives = 68/155 (43%), Gaps = 16/155 (10%) Query: 88 FTKKELQSLYRGF--KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGA 145 +++++ F ++ G + + + + + DADGNG Sbjct: 4 LSEEQIVDFKEAFGLFDKDGDGCITVEELATVIRSLDQNPTEEELQD-MISEVDADGNGT 62 Query: 146 IHFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYP 204 I F++F+ ++ ++ T E+LK AF ++D +++G I+ E+ RH Sbjct: 63 IEFDEFLSLMAKKVKDTDAEEELKEAFKVFDKDQNGYISASEL------------RHVMI 110 Query: 205 ILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETC 239 L E E VE+ ++ D + DG V +EF++ Sbjct: 111 NLGEKLTDEEVEQMIKEADLDGDGQVNYEEFVKMM 145 Score = 60.1 bits (144), Expect = 8e-10, Method: Composition-based stats. Identities = 24/95 (25%), Positives = 44/95 (46%), Gaps = 19/95 (20%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRN 225 K AF L+D + DGCIT EE+ +++S L ++ E ++ ++D + Sbjct: 11 DFKEAFGLFDKDGDGCITVEELATVIRS------------LDQNPTEEELQDMISEVDAD 58 Query: 226 QDGVVTIDEFLETCQKD-------ENIMNSMQLFE 253 +G + DEFL K E + + ++F+ Sbjct: 59 GNGTIEFDEFLSLMAKKVKDTDAEEELKEAFKVFD 93 Score = 48.5 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 24/106 (22%), Positives = 45/106 (42%), Gaps = 1/106 (0%) Query: 89 TKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHF 148 T++ELQ + + G ++ D F + ++ DA F FD D NG I Sbjct: 44 TEEELQDMISE-VDADGNGTIEFDEFLSLMAKKVKDTDAEEELKEAFKVFDKDQNGYISA 102 Query: 149 EDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSI 194 + + L E+++ D++ DG + EE + +M ++ Sbjct: 103 SELRHVMINLGEKLTDEEVEQMIKEADLDGDGQVNYEEFVKMMMTV 148 >4JWQ-A nrPDB Length = 199 Score = 102 bits (254), Expect = 2e-22, Method: Composition-based stats. Identities = 37/159 (23%), Positives = 76/159 (47%), Gaps = 13/159 (8%) Query: 83 QAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADG 142 Q + ++L++++ + +E G + ++ K + L + D+DG Sbjct: 50 QQSNDYDLQQLKTVF-LYLDEDGKGNITKNQLKKGLENSGLKLPQN--FDVLLDQIDSDG 106 Query: 143 NGAIHFEDFVVGLSILLRGTVHEKLKW-AFNLYDINKDGCITKEEMLAIMKSIYDMMGRH 201 +G I + +F+ L R + +KL + AF ++D++ DG IT E+ I+ + G Sbjct: 107 SGRIDYTEFLAA--ALDRKHLSKKLIYCAFRVFDVDNDGEITTAELAHILYN-----GNK 159 Query: 202 TYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQ 240 I ++D + V++ Q++D+N DG + EF E + Sbjct: 160 KGSITQKD--VNQVKKMIQEVDKNNDGKIDFYEFCEMMK 196 Score = 41.6 bits (96), Expect = 3e-04, Method: Composition-based stats. Identities = 16/101 (15%), Positives = 31/101 (30%), Gaps = 5/101 (4%) Query: 62 SSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQF 121 + + S E L + +KK + +R F + G + I Sbjct: 99 LDQIDSDGSGRIDYTEFLAAALDRKHLSKKLIYCAFRVF-DVDNDGEITTAELAHILYNG 157 Query: 122 FPQGDATTY----AHFLFNAFDADGNGAIHFEDFVVGLSIL 158 +G T + D + +G I F +F + + Sbjct: 158 NKKGSITQKDVNQVKKMIQEVDKNNDGKIDFYEFCEMMKLK 198 Score = 38.1 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 13/98 (13%), Positives = 36/98 (36%), Gaps = 13/98 (13%) Query: 152 VVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAP 211 + ++ ++LK F D + G ITK ++ +++ + ++ Sbjct: 45 MTIIAQQSNDYDLQQLKTVFLYLDEDGKGNITKNQLKKGLENSGLKLPQNF--------- 95 Query: 212 LEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSM 249 + ++D + G + EFL +++ + Sbjct: 96 ----DVLLDQIDSDGSGRIDYTEFLAAALDRKHLSKKL 129 >1TOP-A nrPDB Length = 162 Score = 102 bits (253), Expect = 2e-22, Method: Composition-based stats. Identities = 36/167 (21%), Positives = 65/167 (38%), Gaps = 19/167 (11%) Query: 80 DQLQAQTKFTKKELQSLYRGFK--NECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNA 137 Q +A+ +++ + F + G + + + Sbjct: 6 QQAEARAFLSEEMIAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEEL-DAIIEE 64 Query: 138 FDADGNGAIHFEDFVVGLSILLR----GTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS 193 D DG+G I FE+F+V + ++ G E+L F ++D N DG I EE+ I+++ Sbjct: 65 VDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELANCFRIFDKNADGFIDIEELGEILRA 124 Query: 194 IYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQ 240 E E +E + D+N DG + DEFL+ + Sbjct: 125 T------------GEHVTEEDIEDLMKDSDKNNDGRIDFDEFLKMME 159 Score = 51.6 bits (122), Expect = 3e-07, Method: Composition-based stats. Identities = 19/107 (17%), Positives = 46/107 (42%), Gaps = 22/107 (20%) Query: 157 ILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVE 216 L + + K AF+++D + G I+ +E+ +M+ L ++ E ++ Sbjct: 12 AFLSEEMIAEFKAAFDMFDADGGGDISTKELGTVMRM------------LGQNPTKEELD 59 Query: 217 RFFQKMDRNQDGVVTIDEFLETC----------QKDENIMNSMQLFE 253 +++D + G + +EFL + +E + N ++F+ Sbjct: 60 AIIEEVDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELANCFRIFD 106 Score = 50.5 bits (119), Expect = 7e-07, Method: Composition-based stats. Identities = 27/107 (25%), Positives = 43/107 (40%), Gaps = 8/107 (7%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSI 194 F+ FDADG G I ++ + +L + E+L D + G I EE L +M Sbjct: 26 FDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGTIDFEEFLVMMVRQ 85 Query: 195 YDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 + E + F+ D+N DG + I+E E + Sbjct: 86 MKEDAKGK--------SEEELANCFRIFDKNADGFIDIEELGEILRA 124 Score = 48.9 bits (115), Expect = 2e-06, Method: Composition-based stats. Identities = 25/109 (22%), Positives = 45/109 (41%), Gaps = 4/109 (3%) Query: 89 TKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFL---FNAFDADGNGA 145 TK+EL ++ +E +G +D + F ++ + + L F FD + +G Sbjct: 54 TKEELDAIIEE-VDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELANCFRIFDKNADGF 112 Query: 146 IHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSI 194 I E+ L E ++ D N DG I +E L +M+ + Sbjct: 113 IDIEELGEILRATGEHVTEEDIEDLMKDSDKNNDGRIDFDEFLKMMEGV 161 >2TN4-A nrPDB Length = 159 Score = 101 bits (251), Expect = 4e-22, Method: Composition-based stats. Identities = 36/167 (21%), Positives = 65/167 (38%), Gaps = 19/167 (11%) Query: 80 DQLQAQTKFTKKELQSLYRGFK--NECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNA 137 Q +A++ +++ + F + G + + + Sbjct: 3 QQAEARSYLSEEMIAEFKAAFDMFDADGGGDISVKELGTVMRMLGQTPTKEEL-DAIIEE 61 Query: 138 FDADGNGAIHFEDFVVGLSILLR----GTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS 193 D DG+G I FE+F+V + ++ G E+L F ++D N DG I EE+ I ++ Sbjct: 62 VDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELAELFRIFDRNADGYIDAEELAEIFRA 121 Query: 194 IYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQ 240 E E +E + D+N DG + DEFL+ + Sbjct: 122 S------------GEHVTDEEIESLMKDGDKNNDGRIDFDEFLKMME 156 Score = 50.8 bits (120), Expect = 5e-07, Method: Composition-based stats. Identities = 17/98 (17%), Positives = 42/98 (42%), Gaps = 22/98 (22%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRN 225 + K AF+++D + G I+ +E+ +M+ L + E ++ +++D + Sbjct: 18 EFKAAFDMFDADGGGDISVKELGTVMRM------------LGQTPTKEELDAIIEEVDED 65 Query: 226 QDGVVTIDEFLETC----------QKDENIMNSMQLFE 253 G + +EFL + +E + ++F+ Sbjct: 66 GSGTIDFEEFLVMMVRQMKEDAKGKSEEELAELFRIFD 103 Score = 50.5 bits (119), Expect = 7e-07, Method: Composition-based stats. Identities = 27/108 (25%), Positives = 42/108 (38%), Gaps = 8/108 (7%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSI 194 F+ FDADG G I ++ + +L + E+L D + G I EE L +M Sbjct: 23 FDMFDADGGGDISVKELGTVMRMLGQTPTKEELDAIIEEVDEDGSGTIDFEEFLVMMVRQ 82 Query: 195 YDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKD 242 + E + F+ DRN DG + +E E + Sbjct: 83 MKEDAKGK--------SEEELAELFRIFDRNADGYIDAEELAEIFRAS 122 Score = 47.8 bits (112), Expect = 5e-06, Method: Composition-based stats. Identities = 24/109 (22%), Positives = 45/109 (41%), Gaps = 4/109 (3%) Query: 89 TKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFL---FNAFDADGNGA 145 TK+EL ++ +E +G +D + F ++ + + L F FD + +G Sbjct: 51 TKEELDAIIEE-VDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELAELFRIFDRNADGY 109 Query: 146 IHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSI 194 I E+ E+++ D N DG I +E L +M+ + Sbjct: 110 IDAEELAEIFRASGEHVTDEEIESLMKDGDKNNDGRIDFDEFLKMMEGV 158 >2JNF-A nrPDB Length = 158 Score = 100 bits (250), Expect = 5e-22, Method: Composition-based stats. Identities = 38/154 (24%), Positives = 64/154 (41%), Gaps = 18/154 (11%) Query: 91 KELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFED 150 K L++ +R F+ +G V D +I Q +T L + FD GNG I F+ Sbjct: 13 KLLETAFRDFETPEGSGRVSTDQIGIILEVLGIQQTKSTIRQ-LIDEFDPFGNGDIDFDS 71 Query: 151 FVVGLSILL-----RGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPI 205 F + + L + ++L+ AF LYD +G I+ + M I+ Sbjct: 72 FKIIGARFLGEEVNPEQMQQELREAFRLYDKEGNGYISTDVMREILAE------------ 119 Query: 206 LREDAPLEHVERFFQKMDRNQDGVVTIDEFLETC 239 L E E ++ ++D + G V +EF+ Sbjct: 120 LDETLSSEDLDAMIDEIDADGSGTVDFEEFMGVM 153 Score = 45.5 bits (106), Expect = 3e-05, Method: Composition-based stats. Identities = 20/96 (20%), Positives = 41/96 (42%), Gaps = 7/96 (7%) Query: 61 DSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQ 120 D ++ R E ++ Q Q +EL+ +R + E G + D + I ++ Sbjct: 66 DIDFDSFKIIGARFLGEEVNPEQMQ-----QELREAFRLYDKE-GNGYISTDVMREILAE 119 Query: 121 FFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLS 156 + + + DADG+G + FE+F+ ++ Sbjct: 120 LDETLSSEDL-DAMIDEIDADGSGTVDFEEFMGVMT 154 >3K21-A nrPDB Length = 191 Score = 100 bits (248), Expect = 8e-22, Method: Composition-based stats. Identities = 35/141 (24%), Positives = 65/141 (46%), Gaps = 12/141 (8%) Query: 101 KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLR 160 +E G + ++ K + + L + D+DG+G I + +F+ L R Sbjct: 61 LDEDGKGYITKEQLKKGLEKDGLKLPYN--FDLLLDQIDSDGSGKIDYTEFIAA--ALDR 116 Query: 161 GTVHEKLKW-AFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFF 219 + +KL + AF ++D++ DG IT E+ I+ + G I + D + V+R Sbjct: 117 KQLSKKLIYCAFRVFDVDNDGEITTAELAHILYN-----GNKKGNITQRD--VNRVKRMI 169 Query: 220 QKMDRNQDGVVTIDEFLETCQ 240 + +D+N DG + EF E + Sbjct: 170 RDVDKNNDGKIDFHEFSEMMK 190 Score = 43.9 bits (102), Expect = 7e-05, Method: Composition-based stats. Identities = 16/98 (16%), Positives = 36/98 (36%), Gaps = 13/98 (13%) Query: 152 VVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAP 211 + ++ EKLK F + D + G ITKE++ ++ + + +L Sbjct: 39 MTIIAQQSNDYDVEKLKSTFLVLDEDGKGYITKEQLKKGLEKDGLKLPYNFDLLLD---- 94 Query: 212 LEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSM 249 ++D + G + EF+ + + + Sbjct: 95 ---------QIDSDGSGKIDYTEFIAAALDRKQLSKKL 123 >1DTL-A nrPDB Length = 161 Score = 99.4 bits (246), Expect = 1e-21, Method: Composition-based stats. Identities = 34/163 (20%), Positives = 66/163 (40%), Gaps = 17/163 (10%) Query: 82 LQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDAD 141 ++ T+ K E ++ + F G + + + + D D Sbjct: 9 VEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPTPEEL-QEMIDEVDED 67 Query: 142 GNGAIHFEDFVVGLSILLR----GTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDM 197 G+G + F++F+V + ++ G E+L F ++D N DG I EE+ ++++ Sbjct: 68 GSGTVDFDEFLVMMVRSMKDDSKGKSEEELSDLFRMFDKNADGYIDLEELKIMLQAT--- 124 Query: 198 MGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQ 240 E + +E + D+N DG + DEFLE + Sbjct: 125 ---------GETITEDDIEELMKDGDKNNDGRIDYDEFLEFMK 158 Score = 47.4 bits (111), Expect = 6e-06, Method: Composition-based stats. Identities = 27/109 (24%), Positives = 43/109 (39%), Gaps = 4/109 (3%) Query: 89 TKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFL---FNAFDADGNGA 145 T +ELQ + +E +G VD D F ++ + L F FD + +G Sbjct: 53 TPEELQEMIDE-VDEDGSGTVDFDEFLVMMVRSMKDDSKGKSEEELSDLFRMFDKNADGY 111 Query: 146 IHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSI 194 I E+ + L + ++ D N DG I +E L MK + Sbjct: 112 IDLEELKIMLQATGETITEDDIEELMKDGDKNNDGRIDYDEFLEFMKGV 160 Score = 42.0 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 18/99 (18%), Positives = 39/99 (39%), Gaps = 8/99 (8%) Query: 143 NGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHT 202 +G+I ++ + +L + E+L+ + D + G + +E L +M + Sbjct: 33 DGSISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRSMKDDSKGK 92 Query: 203 YPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 E + F+ D+N DG + ++E Q Sbjct: 93 --------SEEELSDLFRMFDKNADGYIDLEELKIMLQA 123 Score = 39.7 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 20/112 (17%), Positives = 44/112 (39%), Gaps = 23/112 (20%) Query: 153 VGLSILLRGTVHEKLKWAFNLYDINK-DGCITKEEMLAIMKSIYDMMGRHTYPILREDAP 211 L + K AF+++ + DG I+ +E+ +M+ L ++ Sbjct: 6 KAAVEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRM------------LGQNPT 53 Query: 212 LEHVERFFQKMDRNQDGVVTIDEFLETC----------QKDENIMNSMQLFE 253 E ++ ++D + G V DEFL + +E + + ++F+ Sbjct: 54 PEELQEMIDEVDEDGSGTVDFDEFLVMMVRSMKDDSKGKSEEELSDLFRMFD 105 >4RGJ-A nrPDB Length = 520 Score = 99.0 bits (245), Expect = 2e-21, Method: Composition-based stats. Identities = 44/223 (19%), Positives = 79/223 (35%), Gaps = 34/223 (15%) Query: 39 RQALMRCCLIKWI--LSSAAPQGSDSSDSELELSTVRH--QPEGLDQLQ----AQTKFTK 90 R + +WI ++S D EL ++ +R + L Q T Sbjct: 308 RISARDALEHEWIKMMTSKDNLNIDIPSLELSIANIRQFQSTQKLAQAALLYMGSKLTTI 367 Query: 91 KELQSLYRGFKNEC--PTGLVDEDTFKLIYSQFFPQGDATTY----------AHFLFNAF 138 E + L + FK G +D + + Y + T + N+ Sbjct: 368 DETKELTKIFKKMDKNGDGQLDRNELIIGYKELLKLKGEDTSDLDNAAIEYEVDQILNSI 427 Query: 139 DADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMM 198 D D NG I + +F+ E+L+ AF L+D + G I+ E+ + + D+ Sbjct: 428 DLDQNGYIEYSEFLTVSIDRKLLLSTERLEKAFKLFDKDGSGKISANELAQLF-GLSDVS 486 Query: 199 GRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 +L +++D+N DG + EF + K Sbjct: 487 SECWKTVL-------------KEVDQNNDGEIDFKEFRDMLVK 516 >3O4Y-A nrPDB Length = 196 Score = 98.6 bits (244), Expect = 2e-21, Method: Composition-based stats. Identities = 31/141 (21%), Positives = 63/141 (44%), Gaps = 12/141 (8%) Query: 101 KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLR 160 +E G + + + + L + D+DG+G I + +F+ + R Sbjct: 64 LDEEGKGNITKLQLRKGLERSGLMLPPN--FDLLLDQIDSDGSGNIDYTEFLAA--AIDR 119 Query: 161 GTVHEKLKW-AFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFF 219 + +KL + AF ++D++ DG IT E+ ++ + G I D + V++ Sbjct: 120 RQLSKKLIYCAFRVFDVDNDGEITTAELAHVLFN-----GNKRGNITERD--VNQVKKMI 172 Query: 220 QKMDRNQDGVVTIDEFLETCQ 240 +++D+N DG + EF E + Sbjct: 173 REVDKNGDGKIDFYEFSEMMK 193 Score = 40.4 bits (93), Expect = 7e-04, Method: Composition-based stats. Identities = 17/102 (16%), Positives = 35/102 (34%), Gaps = 5/102 (4%) Query: 62 SSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQF 121 + + S E L + + +KK + +R F + G + + Sbjct: 96 LDQIDSDGSGNIDYTEFLAAAIDRRQLSKKLIYCAFRVF-DVDNDGEITTAELAHVLFNG 154 Query: 122 FPQGDATTY----AHFLFNAFDADGNGAIHFEDFVVGLSILL 159 +G+ T + D +G+G I F +F + + L Sbjct: 155 NKRGNITERDVNQVKKMIREVDKNGDGKIDFYEFSEMMKLTL 196 >2BEC-A nrPDB Length = 202 Score = 98.6 bits (244), Expect = 2e-21, Method: Composition-based stats. Identities = 38/181 (20%), Positives = 73/181 (40%), Gaps = 31/181 (17%) Query: 80 DQLQAQTKFTKKELQSLYRGF--KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNA 137 D ++ +T F++ L L+ F + G + + I + + + Sbjct: 15 DSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQIGAL-----AVNPLGDRIIES 69 Query: 138 FDADGNGAIHFEDFVVGLSIL-----------------LRGTVHEKLKWAFNLYDINKDG 180 F DG+ + F FV L+ + KL +AF LYD+++DG Sbjct: 70 FFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYAFQLYDLDRDG 129 Query: 181 CITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQ 240 I++ EML +++ + + E+ +R Q+ D + DG V+ EF ++ + Sbjct: 130 KISRHEMLQVLRLM-------VGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTKSLE 182 Query: 241 K 241 K Sbjct: 183 K 183 >5JN2-A nrPDB Length = 525 Score = 96.7 bits (239), Expect = 8e-21, Method: Composition-based stats. Identities = 49/223 (21%), Positives = 80/223 (35%), Gaps = 35/223 (15%) Query: 39 RQALMRCCLIKWILSSAAPQGS-DSSDSELELSTVRHQP--EGLDQ---LQAQTKFT--- 89 R + +WI + Q S D + + +R + L Q L +K T Sbjct: 314 RISARDALDHEWIQTYTKEQISVDVPSLDNAILNIRQFQGTQKLAQAALLYMGSKLTSQD 373 Query: 90 -KKELQSLYRGFKNECPTGLVDEDTFKLIYSQFF-------PQGDATTY---AHFLFNAF 138 KEL +++ G +D Y + DA+ + +A Sbjct: 374 ETKELTAIFHKMDKN-GDGQLDRAELIEGYKELMRMKGQDASMLDASAVEHEVDQVLDAV 432 Query: 139 DADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMM 198 D D NG I + +FV E+L+ AF ++D + G I+ E+ I + D+ Sbjct: 433 DFDKNGYIEYSEFVTVAMDRKTLLSRERLERAFRMFDSDNSGKISSTELATIF-GVSDVD 491 Query: 199 GRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 +L E +D+N DG V DEF + K Sbjct: 492 SETWKSVLSE-------------VDKNNDGEVDFDEFQQMLLK 521 Score = 58.5 bits (140), Expect = 3e-09, Method: Composition-based stats. Identities = 27/170 (15%), Positives = 64/170 (37%), Gaps = 12/170 (7%) Query: 96 LYRGFKNECPTGLVD-----EDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFED 150 L R P+ + + + Y++ D + + + N G + Sbjct: 302 LIRKMLTYVPSMRISARDALDHEWIQTYTKEQISVDVPSLDNAILNIRQFQGTQKLAQAA 361 Query: 151 FVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDA 210 + S L ++L F+ D N DG + + E++ K + M G+ +L A Sbjct: 362 LLYMGSKLTSQDETKELTAIFHKMDKNGDGQLDRAELIEGYKELMRMKGQ-DASMLDASA 420 Query: 211 PLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIM------NSMQLFEN 254 V++ +D +++G + EF+ + ++ + ++F++ Sbjct: 421 VEHEVDQVLDAVDFDKNGYIEYSEFVTVAMDRKTLLSRERLERAFRMFDS 470 >3HZT-A nrPDB Length = 467 Score = 95.9 bits (237), Expect = 2e-20, Method: Composition-based stats. Identities = 49/224 (21%), Positives = 77/224 (34%), Gaps = 36/224 (16%) Query: 39 RQALMRCCLIKWILSSAAPQGSDSSDSELELSTVRHQPEGLDQLQAQ-------TKFTK- 90 R + WI+ + + +D L + + Q AQ +K T Sbjct: 251 RISAEEALNHPWIVKFCSQKHTDVGKHALTGALGNMKKFQSSQKLAQAAMLFMGSKLTTL 310 Query: 91 ---KELQSLYRGFKNECPTGLVDEDTFKLIYSQFF-------PQGDATTY---AHFLFNA 137 KEL ++R N G +D Y + D++ + + Sbjct: 311 EETKELTQIFRQLDNN-GDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQIEAEVDHILQS 369 Query: 138 FDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDM 197 D D NG I + +FV E+L AF +D + G IT EE+ + Sbjct: 370 VDFDRNGYIEYSEFVTVCMDKQLLLSRERLLAAFQQFDSDGSGKITNEELGRLF------ 423 Query: 198 MGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 +D V Q+ D+N DG V +EF+E QK Sbjct: 424 -----GVTEVDDETWHQV---LQECDKNNDGEVDFEEFVEMMQK 459 Score = 54.3 bits (129), Expect = 5e-08, Method: Composition-based stats. Identities = 27/176 (15%), Positives = 57/176 (32%), Gaps = 13/176 (7%) Query: 91 KELQSLYRGFKNECPTGLVDEDT------FKLIYSQFFPQGDATTYAHFLFNAFDADGNG 144 E + L + P+ + + SQ L N + Sbjct: 234 DEAKQLVKLMLTYEPSKRISAEEALNHPWIVKFCSQKHTDVGKHALTGALGNMKKFQSSQ 293 Query: 145 AIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYP 204 + + S L ++L F D N DG + ++E++ + + G Sbjct: 294 KLAQAAMLFMGSKLTTLEETKELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSD 353 Query: 205 ILREDAPLEHVERFFQKMDRNQDGVVTIDEFL------ETCQKDENIMNSMQLFEN 254 L V+ Q +D +++G + EF+ + E ++ + Q F++ Sbjct: 354 -LDSSQIEAEVDHILQSVDFDRNGYIEYSEFVTVCMDKQLLLSRERLLAAFQQFDS 408 >4YZB-A nrPDB Length = 491 Score = 95.5 bits (236), Expect = 2e-20, Method: Composition-based stats. Identities = 46/223 (20%), Positives = 80/223 (35%), Gaps = 35/223 (15%) Query: 39 RQALMRCCLIKWILSSAAPQGS-DSSDSELELSTVRHQPEGLDQLQAQTKF-------TK 90 R + +W+ ++ A S D E + +R Q +G +L A T Sbjct: 277 RISARDALEHEWLKTTDAATDSIDVPSLESTILNIR-QFQGTQKLAAAALLYMGSKLTTN 335 Query: 91 KELQSLYRGF--KNECPTGLVDEDTFKLIYSQFFPQG-------DATTY---AHFLFNAF 138 +E L + F ++ G +D+ Y + D + + +A Sbjct: 336 EETVELNKIFQRMDKNGDGQLDKQELMEGYVELMKLKGEDVSALDQSAIEFEVEQVLDAV 395 Query: 139 DADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMM 198 D D NG I + +FV ++L+ AF ++D + G I+ E+ I Sbjct: 396 DFDKNGFIEYSEFVTVAMDRKTLLSRQRLERAFGMFDADGSGKISSSELATIFG------ 449 Query: 199 GRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 + E R ++DRN DG V +EF + K Sbjct: 450 --------VSEVDSETWRRVLAEVDRNNDGEVDFEEFRQMLLK 484 >3LIJ-A nrPDB Length = 494 Score = 94.8 bits (234), Expect = 3e-20, Method: Composition-based stats. Identities = 40/220 (18%), Positives = 75/220 (34%), Gaps = 31/220 (14%) Query: 39 RQALMRCCLIKWILSS--------AAPQGSDSSDSELELSTVRHQPEGLDQLQAQTKFTK 90 R + + WI P +++ ++ + + + A ++ Sbjct: 283 RISAQQALEHPWIKEMCSKKESGIELPSLANAIENMRKFQNSQKLAQAALLYMASKLTSQ 342 Query: 91 KELQSLYRGF--KNECPTGLVDEDTFKLIYSQF-------FPQGDATTYAHFLFNAFDAD 141 +E + L F ++ G +D YS+ F + + A D D Sbjct: 343 EETKELTDIFRHIDKNGDGQLDRQELIDGYSKLSGEEVAVFDLPQIESEVDAILGAADFD 402 Query: 142 GNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRH 201 NG I + +FV +KL+ AF +D + +G I+ +E+ ++ Sbjct: 403 RNGYIDYSEFVTVAMDRKSLLSKDKLESAFQKFDQDGNGKISVDELASVF---------- 452 Query: 202 TYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 L E +D N DG V +EF + QK Sbjct: 453 GLDHLESKTWKE----MISGIDSNNDGDVDFEEFCKMIQK 488 Score = 50.8 bits (120), Expect = 6e-07, Method: Composition-based stats. Identities = 17/108 (15%), Positives = 40/108 (37%), Gaps = 10/108 (9%) Query: 152 VVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAP 211 + S L ++L F D N DG + ++E++ Y + + Sbjct: 333 LYMASKLTSQEETKELTDIFRHIDKNGDGQLDRQELID----GYSKLSGEEVAVFDLPQI 388 Query: 212 LEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIM------NSMQLFE 253 V+ D +++G + EF+ ++++ ++ Q F+ Sbjct: 389 ESEVDAILGAADFDRNGYIDYSEFVTVAMDRKSLLSKDKLESAFQKFD 436 >3Q5I-A nrPDB Length = 504 Score = 94.4 bits (233), Expect = 5e-20, Method: Composition-based stats. Identities = 46/221 (20%), Positives = 78/221 (35%), Gaps = 34/221 (15%) Query: 39 RQALMRCCLIKWILSSAAPQGSDSSDSELELSTVRHQPEGLDQLQAQ-------TKFT-- 89 R +WI A + S L + + Q AQ +K T Sbjct: 293 RCTAEEALNSRWI-KKYANNINKSDQKTLCGALSNMRKFEGSQKLAQAAILFIGSKLTTL 351 Query: 90 --KKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDA-------TTYAHFLFNAFDA 140 +KEL +++ G +D+ Y+ + + D Sbjct: 352 EERKELTDIFKKLDKN-GDGQLDKKELIEGYNVLRNFKNELGELKNVEEEVDNILKEVDF 410 Query: 141 DGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGR 200 D NG I + +F+ E+L+ AFNL+D +K G ITKEE+ + + + + Sbjct: 411 DKNGYIEYSEFISVCMDKQILFSEERLRRAFNLFDTDKSGKITKEELANLF-GLTSISEK 469 Query: 201 HTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 +L E D+N+D ++ DEF+ K Sbjct: 470 TWNDVLGE-------------ADQNKDNMIDFDEFVSMMHK 497 Score = 51.2 bits (121), Expect = 4e-07, Method: Composition-based stats. Identities = 19/96 (19%), Positives = 40/96 (41%), Gaps = 10/96 (10%) Query: 164 HEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMD 223 ++L F D N DG + K+E++ + + E E V+ +++D Sbjct: 354 RKELTDIFKKLDKNGDGQLDKKELIEGYNVLRNFKNELGELKNVE----EEVDNILKEVD 409 Query: 224 RNQDGVVTIDEFLETCQ------KDENIMNSMQLFE 253 +++G + EF+ C +E + + LF+ Sbjct: 410 FDKNGYIEYSEFISVCMDKQILFSEERLRRAFNLFD 445 >2BL0-C nrPDB Length = 142 Score = 92.4 bits (228), Expect = 2e-19, Method: Composition-based stats. Identities = 34/150 (22%), Positives = 63/150 (42%), Gaps = 16/150 (10%) Query: 91 KELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFED 150 E + + F +E TG + ++ + + QF + + + +FN DA GNG I F + Sbjct: 6 SEFKEAFELFDSE-RTGFITKEGLQTVLKQFGVRVEPAAFNE-MFNEADATGNGKIQFPE 63 Query: 151 FVVGLSILLRGTVHEK-LKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILRED 209 F+ + ++ T E L+ AF +D G I K + + ++ D + H + E Sbjct: 64 FLSMMGRRMKQTTSEDILRQAFRTFDPEGTGYIPKAALQDALLNLGDRLKPHEF---AEF 120 Query: 210 APLEHVERFFQKMDRNQDGVVTIDEFLETC 239 + E+ G + D F+ T Sbjct: 121 LGITETEK----------GQIRYDNFINTM 140 Score = 48.9 bits (115), Expect = 2e-06, Method: Composition-based stats. Identities = 17/76 (22%), Positives = 29/76 (38%), Gaps = 12/76 (15%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRN 225 + K AF L+D + G ITKE + ++K + + F + D Sbjct: 7 EFKEAFELFDSERTGFITKEGLQTVLKQFGVRVEPAAF------------NEMFNEADAT 54 Query: 226 QDGVVTIDEFLETCQK 241 +G + EFL + Sbjct: 55 GNGKIQFPEFLSMMGR 70 >1S6I-A nrPDB Length = 188 Score = 92.4 bits (228), Expect = 2e-19, Method: Composition-based stats. Identities = 31/157 (19%), Positives = 63/157 (40%), Gaps = 17/157 (10%) Query: 87 KFTKKELQSLYRGFK--NECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNG 144 + +++E+ L FK + +G + D K + + + + +A D D +G Sbjct: 3 RLSEEEIGGLKELFKMIDTDNSGTITFDELKDGLKRVGSELMESEIKDLM-DAADIDKSG 61 Query: 145 AIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYP 204 I + +F+ L + E L AF+ +D + G IT +E+ K Sbjct: 62 TIDYGEFIAATVHLNKLEREENLVSAFSYFDKDGSGYITLDEIQQACKDFG--------- 112 Query: 205 ILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 H++ +++D++ DG + EF +K Sbjct: 113 -----LDDIHIDDMIKEIDQDNDGQIDYGEFAAMMRK 144 >2AAO-A nrPDB Length = 166 Score = 89.8 bits (221), Expect = 1e-18, Method: Composition-based stats. Identities = 28/156 (17%), Positives = 59/156 (37%), Gaps = 17/156 (10%) Query: 88 FTKKELQSLYRGF--KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGA 145 +++E+ L F + +G + + K + + + A D D +G Sbjct: 21 LSEEEIAGLKEMFNMIDADKSGQITFEELKAGLKRVGANLKESEILDLM-QAADVDNSGT 79 Query: 146 IHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPI 205 I +++F+ L + + L AF +D + G IT +E+ + Sbjct: 80 IDYKEFIAATLHLNKIEREDHLFAAFTYFDKDGSGYITPDELQQACEEFGVE-------- 131 Query: 206 LREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 +E + +D++ DG + +EF+ QK Sbjct: 132 ------DVRIEELMRDVDQDNDGRIDYNEFVAMMQK 161 >2LMV-A nrPDB Length = 148 Score = 89.0 bits (219), Expect = 2e-18, Method: Composition-based stats. Identities = 28/160 (17%), Positives = 64/160 (40%), Gaps = 16/160 (10%) Query: 86 TKFTKKELQSLYRGF--KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGN 143 ++ T++++ F ++ TG + + L + + N Sbjct: 2 SELTEEQIAEFKDAFVQFDKEGTGKIATRELGTLMRTLGQNPTEAELQD-LIAEAENNNN 60 Query: 144 GAIHFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHT 202 G ++F +F ++ +R T E+++ AF ++D + DG I+ E+ R Sbjct: 61 GQLNFTEFCGIMAKQMRETDTEEEMREAFKIFDRDGDGFISPAEL------------RFV 108 Query: 203 YPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKD 242 L E E ++ ++ D + DG++ +EF+ + Sbjct: 109 MINLGEKVTDEEIDEMIREADFDGDGMINYEEFVWMISQK 148 >4MVF-A nrPDB Length = 506 Score = 88.6 bits (218), Expect = 2e-18, Method: Composition-based stats. Identities = 35/209 (16%), Positives = 68/209 (32%), Gaps = 17/209 (8%) Query: 39 RQALMRCCLIKWIL----SSAAPQGSDSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQ 94 R + WI S + S + L+ ++ + + E+ Sbjct: 301 RCTIEEALNHPWITQMTKSHEHVELSSTLLKNLKNFKKENELKKIALTIIAKHLCDVEIN 360 Query: 95 SLYRGF--KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFV 152 +L F + +G + + Q H + D++ +G IH+ DF+ Sbjct: 361 NLRNIFIALDVDNSGTLSSQEILDGLKKIGYQKIP-PDIHQVLRDIDSNASGQIHYTDFL 419 Query: 153 VGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPL 212 E F +DI+ +G I+ EE+ I + Sbjct: 420 AATIDKQTYLKKEVCLIPFKFFDIDGNGKISVEELKRIF----------GRDDIENPLID 469 Query: 213 EHVERFFQKMDRNQDGVVTIDEFLETCQK 241 + ++ Q++D N DG + EF+ K Sbjct: 470 KAIDSLLQEVDLNGDGEIDFHEFMLMMSK 498 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 19/110 (17%), Positives = 40/110 (36%), Gaps = 12/110 (10%) Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS 193 +F A D D +G + ++ + GL + + + D N G I + LA Sbjct: 365 IFIALDVDNSGTLSSQEILDGLKKIGYQKIPPDIHQVLRDIDSNASGQIHYTDFLAATID 424 Query: 194 IYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDE 243 + + I F+ D + +G ++++E +D+ Sbjct: 425 KQTYLKKEVCLIP------------FKFFDIDGNGKISVEELKRIFGRDD 462 Score = 35.1 bits (79), Expect = 0.031, Method: Composition-based stats. Identities = 13/81 (16%), Positives = 29/81 (35%), Gaps = 12/81 (14%) Query: 167 LKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQ 226 L+ F D++ G ++ +E+L +K I + + + +D N Sbjct: 362 LRNIFIALDVDNSGTLSSQEILDGLKKIGYQKIP------------PDIHQVLRDIDSNA 409 Query: 227 DGVVTIDEFLETCQKDENIMN 247 G + +FL + + Sbjct: 410 SGQIHYTDFLAATIDKQTYLK 430 >2LHI-A nrPDB Length = 176 Score = 87.8 bits (216), Expect = 4e-18, Method: Composition-based stats. Identities = 30/161 (18%), Positives = 59/161 (36%), Gaps = 17/161 (10%) Query: 84 AQTKFTKKELQSLYRGF--KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDAD 141 + T++++ F ++ G + + + N D D Sbjct: 1 GSSNLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLM-NEIDVD 59 Query: 142 GNGAIHFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGR 200 GN I F +F+ +S L+ ++L AF ++D N DG I+ E+ ++ SI Sbjct: 60 GNHQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSI------ 113 Query: 201 HTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 E V+ +++ + G + I +F K Sbjct: 114 ------GEKLTDAEVDDMLREV-SDGSGEINIQQFAALLSK 147 >4DS7-A nrPDB Length = 147 Score = 87.1 bits (214), Expect = 7e-18, Method: Composition-based stats. Identities = 32/158 (20%), Positives = 61/158 (38%), Gaps = 17/158 (10%) Query: 87 KFTKKELQSLYRGF--KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNG 144 T++++ F ++ +G + + A + N D DGN Sbjct: 4 NLTEEQIAEFKEAFALFDKDNSGSISASELATVMRSLGLSPSEAEVADLM-NEIDVDGNH 62 Query: 145 AIHFEDFVVGLSILLR-GTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTY 203 AI F +F+ +S L+ ++L AF ++D N DG I+ E+ ++ SI Sbjct: 63 AIEFSEFLALMSRQLKCNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSI--------- 113 Query: 204 PILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 E V+ +++ + G + I +F K Sbjct: 114 ---GEKLTDAEVDEMLREV-SDGSGEINIKQFAALLSK 147 >1LKJ-A nrPDB Length = 146 Score = 84.0 bits (206), Expect = 5e-17, Method: Composition-based stats. Identities = 30/160 (18%), Positives = 59/160 (36%), Gaps = 17/160 (10%) Query: 85 QTKFTKKELQSLYRGF--KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADG 142 + T++++ F ++ G + + + N D DG Sbjct: 1 SSNLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLM-NEIDVDG 59 Query: 143 NGAIHFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRH 201 N I F +F+ +S L+ ++L AF ++D N DG I+ E+ ++ SI Sbjct: 60 NHQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSI------- 112 Query: 202 TYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 E V+ +++ + G + I +F K Sbjct: 113 -----GEKLTDAEVDDMLREV-SDGSGEINIQQFAALLSK 146 >5D43-A nrPDB Length = 178 Score = 82.8 bits (203), Expect = 1e-16, Method: Composition-based stats. Identities = 34/159 (21%), Positives = 65/159 (40%), Gaps = 18/159 (11%) Query: 87 KFTKKELQSLYRGFK--NECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNG 144 + T+ + Q + F + +G +D K+ + + + D + G Sbjct: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMK-KMISEVDKEATG 82 Query: 145 AIHFEDFVVGLSILL--RGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHT 202 I F DF+ ++ + + T E LK AF L+D ++ G I+ + + + Sbjct: 83 KISFNDFLAVMTQKMAEKDTKEEILK-AFRLFDDDETGKISFKNL------------KRV 129 Query: 203 YPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 L E E ++ + DR+ DG V +EFL+ +K Sbjct: 130 ANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKK 168 Score = 43.5 bits (101), Expect = 8e-05, Method: Composition-based stats. Identities = 24/93 (25%), Positives = 40/93 (43%) Query: 102 NECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRG 161 ++ TG + + F + +Q + D F FD D G I F++ + L Sbjct: 77 DKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGES 136 Query: 162 TVHEKLKWAFNLYDINKDGCITKEEMLAIMKSI 194 E+L+ + D + DG + +EE L IMK Sbjct: 137 LTDEELQEMIDEADRDGDGEVNEEEFLKIMKKT 169 >3KHE-A nrPDB Length = 191 Score = 82.0 bits (201), Expect = 2e-16, Method: Composition-based stats. Identities = 39/162 (24%), Positives = 59/162 (36%), Gaps = 25/162 (15%) Query: 90 KKELQSLYRGFKNECPTGLVDEDTFKLIYSQFF-------PQGDATTY---AHFLFNAFD 139 KEL ++R N G +D Y + D++ + + D Sbjct: 39 TKELTQIFRQLDNN-GDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQIEAEVDHILQSVD 97 Query: 140 ADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMG 199 D NG I + +FV E+L AF +D + G IT EE+ + Sbjct: 98 FDRNGYIEYSEFVTVCMDKQLLLSRERLLAAFQQFDSDGSGKITNEELGRLF-------- 149 Query: 200 RHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 +D V Q+ D+N DG V +EF+E QK Sbjct: 150 ---GVTEVDDETWHQV---LQECDKNNDGEVDFEEFVEMMQK 185 Score = 50.5 bits (119), Expect = 7e-07, Method: Composition-based stats. Identities = 18/96 (18%), Positives = 40/96 (41%), Gaps = 7/96 (7%) Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDR 224 ++L F D N DG + ++E++ + + G L V+ Q +D Sbjct: 40 KELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSD-LDSSQIEAEVDHILQSVDF 98 Query: 225 NQDGVVTIDEFL------ETCQKDENIMNSMQLFEN 254 +++G + EF+ + E ++ + Q F++ Sbjct: 99 DRNGYIEYSEFVTVCMDKQLLLSRERLLAAFQQFDS 134 >3PM8-A nrPDB Length = 197 Score = 81.3 bits (199), Expect = 3e-16, Method: Composition-based stats. Identities = 29/160 (18%), Positives = 55/160 (34%), Gaps = 13/160 (8%) Query: 86 TKFTKKELQSLYRGF--KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGN 143 E+ +L F + +G + + Q H + D++ + Sbjct: 49 KHLCDVEINNLRNIFIALDVDNSGTLSSQEILDGLKKIGYQKIP-PDIHQVLRDIDSNAS 107 Query: 144 GAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTY 203 G IH+ DF+ E F +DI+ +G I+ EE+ I Sbjct: 108 GQIHYTDFLAATIDKQTYLKKEVCLIPFKFFDIDGNGKISVEELKRIF----------GR 157 Query: 204 PILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDE 243 + + ++ Q++D N DG + EF+ K + Sbjct: 158 DDIENPLIDKAIDSLLQEVDLNGDGEIDFHEFMLMMSKKK 197 Score = 33.5 bits (75), Expect = 0.086, Method: Composition-based stats. Identities = 13/81 (16%), Positives = 29/81 (35%), Gaps = 12/81 (14%) Query: 167 LKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQ 226 L+ F D++ G ++ +E+L +K I + + + +D N Sbjct: 59 LRNIFIALDVDNSGTLSSQEILDGLKKIGYQKIP------------PDIHQVLRDIDSNA 106 Query: 227 DGVVTIDEFLETCQKDENIMN 247 G + +FL + + Sbjct: 107 SGQIHYTDFLAATIDKQTYLK 127 >2LAP-A nrPDB Length = 167 Score = 81.3 bits (199), Expect = 4e-16, Method: Composition-based stats. Identities = 31/156 (19%), Positives = 56/156 (35%), Gaps = 18/156 (11%) Query: 91 KELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFED 150 +EL+ +R F + G ++ L + + G + F+D Sbjct: 25 EELREAFREFDKD-KDGYINCRDLGNCMRTMGYMPTEMELIE-LSQQINMNLGGHVDFDD 82 Query: 151 FVVGLSILLRGTVHE-----KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPI 205 FV + L + +L+ AF +D N DG I+ E+ M+ + Sbjct: 83 FVELMGPKLLAETADMIGVKELRDAFREFDTNGDGEISTSELREAMRKL----------- 131 Query: 206 LREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 L +E + +D N DG V +EF+ + Sbjct: 132 LGHQVGHRDIEEIIRDVDLNGDGRVDFEEFVRMMSR 167 >2GGM-A nrPDB Length = 172 Score = 81.3 bits (199), Expect = 4e-16, Method: Composition-based stats. Identities = 33/158 (20%), Positives = 67/158 (42%), Gaps = 16/158 (10%) Query: 87 KFTKKELQSLYRGFK--NECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNG 144 + T+++ Q + F + TG +D K+ + + + D +G G Sbjct: 24 ELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEEIK-KMISEIDKEGTG 82 Query: 145 AIHFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTY 203 ++F DF+ ++ + E++ AF L+D ++ G I+ + + + K Sbjct: 83 KMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKE---------- 132 Query: 204 PILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 L E+ E ++ + DR+ DG V+ EFL +K Sbjct: 133 --LGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKK 168 Score = 42.8 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 26/105 (24%), Positives = 45/105 (42%), Gaps = 1/105 (0%) Query: 90 KKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFE 149 K+E++ + E TG ++ F + +Q + D F FD D G I F+ Sbjct: 66 KEEIKKMISEIDKE-GTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFK 124 Query: 150 DFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSI 194 + L E+L+ + D + DG ++++E L IMK Sbjct: 125 NLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKKT 169 >3L19-A nrPDB Length = 214 Score = 80.9 bits (198), Expect = 4e-16, Method: Composition-based stats. Identities = 37/196 (18%), Positives = 70/196 (35%), Gaps = 23/196 (11%) Query: 55 AAPQGSDSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGF--KNECPTGLVDED 112 P +++ ++ + + + A +++E + L F ++ G +D Sbjct: 24 ELPSLANAIENMRKFQNSQKLAQAALLYMASKLTSQEETKELTDIFRHIDKNGDGQLDRQ 83 Query: 113 TFKLIYSQF-------FPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHE 165 YS+ F + + A D D NG I + +FV + Sbjct: 84 ELIDGYSKLSGEEVAVFDLPQIESEVDAILGAADFDRNGYIDYSEFVTVAMDRKSLLSKD 143 Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRN 225 KL+ AF +D + +G I+ +E+ ++ L E +D N Sbjct: 144 KLESAFQKFDQDGNGKISVDELASVF----------GLDHLESKTWKE----MISGIDSN 189 Query: 226 QDGVVTIDEFLETCQK 241 DG V +EF + QK Sbjct: 190 NDGDVDFEEFCKMIQK 205 Score = 48.5 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 16/100 (16%), Positives = 38/100 (38%), Gaps = 4/100 (4%) Query: 152 VVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAP 211 + S L ++L F D N DG + ++E++ Y + + Sbjct: 50 LYMASKLTSQEETKELTDIFRHIDKNGDGQLDRQELID----GYSKLSGEEVAVFDLPQI 105 Query: 212 LEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQL 251 V+ D +++G + EF+ +++++ +L Sbjct: 106 ESEVDAILGAADFDRNGYIDYSEFVTVAMDRKSLLSKDKL 145 >2JNX-A nrPDB Length = 134 Score = 80.9 bits (198), Expect = 5e-16, Method: Composition-based stats. Identities = 38/139 (27%), Positives = 53/139 (38%), Gaps = 20/139 (14%) Query: 101 KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVV-GLSILL 159 + G V + K S P + +F A D DGNG I +F ++ Sbjct: 9 LDANGDGSVSYEEVKAFVSSKRPIKNEQLL-QLIFKAIDIDGNGEIDLAEFTKFAAAVKE 67 Query: 160 RGTVHEK--LKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVER 217 + EK LK + L D + DG +TKEE+ K E V Sbjct: 68 QDLSDEKVGLKILYKLMDADGDGKLTKEEVTTFFKKFGY----------------EKVVD 111 Query: 218 FFQKMDRNQDGVVTIDEFL 236 K D N DG +T++EFL Sbjct: 112 QIMKADANGDGYITLEEFL 130 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 29/72 (40%), Gaps = 12/72 (16%) Query: 170 AFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGV 229 F D N DG ++ EE+ A + S + + ++ F+ +D + +G Sbjct: 5 LFKQLDANGDGSVSYEEVKAFVSSKRPIKN------------EQLLQLIFKAIDIDGNGE 52 Query: 230 VTIDEFLETCQK 241 + + EF + Sbjct: 53 IDLAEFTKFAAA 64 Score = 28.1 bits (61), Expect = 3.8, Method: Composition-based stats. Identities = 10/41 (24%), Positives = 19/41 (46%), Gaps = 5/41 (12%) Query: 214 HVERFFQKMDRNQDGVVTIDEFLETCQ-----KDENIMNSM 249 E F+++D N DG V+ +E K+E ++ + Sbjct: 1 MAEALFKQLDANGDGSVSYEEVKAFVSSKRPIKNEQLLQLI 41 >2HF5-A nrPDB Length = 68 Score = 79.4 bits (194), Expect = 2e-15, Method: Composition-based stats. Identities = 19/65 (29%), Positives = 38/65 (58%), Gaps = 1/65 (1%) Query: 132 HFLFNAFDADGNGAIHFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKDGCITKEEMLAI 190 + N DADGNG I F +F+ ++ ++ T E+++ AF ++D + +G I+ E+ + Sbjct: 4 QDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHV 63 Query: 191 MKSIY 195 M ++ Sbjct: 64 MTNLG 68 Score = 34.7 bits (78), Expect = 0.046, Method: Composition-based stats. Identities = 8/47 (17%), Positives = 20/47 (42%), Gaps = 7/47 (14%) Query: 214 HVERFFQKMDRNQDGVVTIDEFLETCQKD-------ENIMNSMQLFE 253 ++ ++D + +G + EFL + E I + ++F+ Sbjct: 2 ELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFD 48 Score = 33.9 bits (76), Expect = 0.065, Method: Composition-based stats. Identities = 11/65 (16%), Positives = 24/65 (36%), Gaps = 11/65 (16%) Query: 175 DINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDE 234 D + +G I E L +M +++ E + F+ D++ +G ++ E Sbjct: 11 DADGNGTIDFPEFLTMM-----------ARKMKDTDSEEEIREAFRVFDKDGNGYISAAE 59 Query: 235 FLETC 239 Sbjct: 60 LRHVM 64 Score = 33.5 bits (75), Expect = 0.089, Method: Composition-based stats. Identities = 12/49 (24%), Positives = 19/49 (38%) Query: 102 NECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFED 150 + G +D F + ++ D+ F FD DGNG I + Sbjct: 11 DADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAE 59 >5ZOR-A nrPDB Length = 149 Score = 77.8 bits (190), Expect = 4e-15, Method: Composition-based stats. Identities = 26/153 (16%), Positives = 60/153 (39%), Gaps = 14/153 (9%) Query: 88 FTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIH 147 T ++++ + F + +G +D + L + + + NG I Sbjct: 4 LTDEQIREAFNLFDAD-GSGAIDAEEMALAMKGLGFGDLPRDEVERTVRSMNTNANGLIE 62 Query: 148 FEDFVVGL-SILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPIL 206 + +F + S + + E++ AF L+D++K G I+ + + +L Sbjct: 63 YGEFERMVKSRMAQKDSPEEVLKAFQLFDLDKKGKISFANL------------KEVAKLL 110 Query: 207 REDAPLEHVERFFQKMDRNQDGVVTIDEFLETC 239 E+ + ++ + D + DG V+ +EF Sbjct: 111 GENPGDDVLQEMIAEADEDGDGEVSFEEFKSVM 143 Score = 65.1 bits (157), Expect = 3e-11, Method: Composition-based stats. Identities = 30/102 (29%), Positives = 47/102 (46%), Gaps = 18/102 (17%) Query: 159 LRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERF 218 + E+++ AFNL+D + G I EEM MK + D P + VER Sbjct: 1 MAALTDEQIREAFNLFDADGSGAIDAEEMALAMKGLGF-----------GDLPRDEVERT 49 Query: 219 FQKMDRNQDGVVTIDEF-----LETCQKD--ENIMNSMQLFE 253 + M+ N +G++ EF QKD E ++ + QLF+ Sbjct: 50 VRSMNTNANGLIEYGEFERMVKSRMAQKDSPEEVLKAFQLFD 91 Score = 40.1 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 23/107 (21%), Positives = 41/107 (38%), Gaps = 1/107 (0%) Query: 88 FTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIH 147 + E++ R N GL++ F+ + Q D+ F FD D G I Sbjct: 41 LPRDEVERTVRS-MNTNANGLIEYGEFERMVKSRMAQKDSPEEVLKAFQLFDLDKKGKIS 99 Query: 148 FEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSI 194 F + +L + L+ D + DG ++ EE ++M + Sbjct: 100 FANLKEVAKLLGENPGDDVLQEMIAEADEDGDGEVSFEEFKSVMMQM 146 >2OBH-A nrPDB Length = 143 Score = 77.0 bits (188), Expect = 7e-15, Method: Composition-based stats. Identities = 33/156 (21%), Positives = 66/156 (42%), Gaps = 16/156 (10%) Query: 89 TKKELQSLYRGFK--NECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAI 146 T+++ Q + F + TG +D K+ + + + D +G G + Sbjct: 1 TEEQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEEIK-KMISEIDKEGTGKM 59 Query: 147 HFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPI 205 +F DF+ ++ + E++ AF L+D ++ G I+ + + + K Sbjct: 60 NFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKE------------ 107 Query: 206 LREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 L E+ E ++ + DR+ DG V+ EFL +K Sbjct: 108 LGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKK 143 >1JFJ-A nrPDB Length = 134 Score = 76.3 bits (186), Expect = 1e-14, Method: Composition-based stats. Identities = 39/138 (28%), Positives = 57/138 (41%), Gaps = 20/138 (14%) Query: 105 PTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGL-SILLRGTV 163 G V + K S+ + +F + DADGNG I +F SI + Sbjct: 13 GDGAVSYEEVKAFVSKKRAIKNEQLL-QLIFKSIDADGNGEIDQNEFAKFYGSIQGQDLS 71 Query: 164 HEK--LKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQK 221 +K LK + L D++ DG +TKEE+ + K +E V K Sbjct: 72 DDKIGLKVLYKLMDVDGDGKLTKEEVTSFFKKHG----------------IEKVAEQVMK 115 Query: 222 MDRNQDGVVTIDEFLETC 239 D N DG +T++EFLE Sbjct: 116 ADANGDGYITLEEFLEFS 133 Score = 30.4 bits (67), Expect = 0.69, Method: Composition-based stats. Identities = 10/32 (31%), Positives = 15/32 (46%) Query: 214 HVERFFQKMDRNQDGVVTIDEFLETCQKDENI 245 E F+++D N DG V+ +E K I Sbjct: 1 MAEALFKEIDVNGDGAVSYEEVKAFVSKKRAI 32 >2M29-A nrPDB Length = 171 Score = 75.9 bits (185), Expect = 2e-14, Method: Composition-based stats. Identities = 27/102 (26%), Positives = 44/102 (43%), Gaps = 16/102 (15%) Query: 144 GAIHFEDFVVGLSILLRGTVHE-----KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMM 198 G + FE+FV +S LR +L+ AF +D ++DG IT E+ ++ Sbjct: 79 GFVDFEEFVELISPKLREETAHMLGVRELRIAFREFDKDRDGRITVAELRQAAPAL---- 134 Query: 199 GRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQ 240 L E ++ ++MD N DG + DEF+ Sbjct: 135 -------LGEPLEGTELDEMLREMDLNGDGTIDFDEFVMMLS 169 Score = 45.8 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 28/69 (40%), Gaps = 1/69 (1%) Query: 88 FTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIH 147 +EL+ +R F + G + + + T + D +G+G I Sbjct: 102 LGVRELRIAFREFDKD-RDGRITVAELRQAAPALLGEPLEGTELDEMLREMDLNGDGTID 160 Query: 148 FEDFVVGLS 156 F++FV+ LS Sbjct: 161 FDEFVMMLS 169 >5MWC-D nrPDB Length = 311 Score = 73.6 bits (179), Expect = 9e-14, Method: Composition-based stats. Identities = 21/89 (23%), Positives = 37/89 (41%), Gaps = 12/89 (13%) Query: 152 VVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAP 211 V+ S+ E+L F +D + DG I +EE I++ + E Sbjct: 138 VMANSLTAMVPSEEELSECFRTFDKDGDGFIDREEFGGIIR------------LTGEQLT 185 Query: 212 LEHVERFFQKMDRNQDGVVTIDEFLETCQ 240 E + F D +++G + DEFL+ + Sbjct: 186 DEDPDEIFGDSDTDKNGRIDFDEFLKMVE 214 Score = 51.2 bits (121), Expect = 4e-07, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 29/67 (43%), Gaps = 2/67 (2%) Query: 89 TKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHF 148 +++EL +R F + G +D + F I Q +F D D NG I F Sbjct: 149 SEEELSECFRTFDKD-GDGFIDREEFGGIIRLTGEQLTDED-PDEIFGDSDTDKNGRIDF 206 Query: 149 EDFVVGL 155 ++F+ + Sbjct: 207 DEFLKMV 213 Score = 50.5 bits (119), Expect = 7e-07, Method: Composition-based stats. Identities = 17/60 (28%), Positives = 29/60 (48%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSI 194 F FD DG+G I E+F + + E F D +K+G I +E L +++++ Sbjct: 157 FRTFDKDGDGFIDREEFGGIIRLTGEQLTDEDPDEIFGDSDTDKNGRIDFDEFLKMVENV 216 >2LHH-A nrPDB Length = 128 Score = 73.2 bits (178), Expect = 1e-13, Method: Composition-based stats. Identities = 24/117 (20%), Positives = 48/117 (41%), Gaps = 4/117 (3%) Query: 85 QTKFTKKELQSLYRGF--KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADG 142 + T++++ F ++ G + + + N D DG Sbjct: 1 SSNLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLM-NEIDVDG 59 Query: 143 NGAIHFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMM 198 N I F +F+ +S L+ ++L AF ++D N DG I+ E+ ++ SI + + Sbjct: 60 NHQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKL 116 Score = 52.0 bits (123), Expect = 2e-07, Method: Composition-based stats. Identities = 17/95 (17%), Positives = 39/95 (41%), Gaps = 19/95 (20%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRN 225 + K AF L+D + +G I+ E+ +M+S L V ++D + Sbjct: 11 EFKEAFALFDKDNNGSISSSELATVMRS------------LGLSPSEAEVNDLMNEIDVD 58 Query: 226 QDGVVTIDEFLETCQK-------DENIMNSMQLFE 253 + + EFL + ++ ++ + ++F+ Sbjct: 59 GNHQIEFSEFLALMSRQLKSNDSEQELLEAFKVFD 93 >1FW4-A nrPDB Length = 71 Score = 73.2 bits (178), Expect = 1e-13, Method: Composition-based stats. Identities = 19/77 (24%), Positives = 35/77 (45%), Gaps = 12/77 (15%) Query: 163 VHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKM 222 E+++ AF ++D + +G I+ E+ RH L E E V+ ++ Sbjct: 4 SEEEIREAFRVFDKDGNGYISAAEL------------RHVMTNLGEKLTDEEVDEMIREA 51 Query: 223 DRNQDGVVTIDEFLETC 239 D + DG V +EF++ Sbjct: 52 DIDGDGQVNYEEFVQMM 68 Score = 42.0 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 11/70 (15%), Positives = 31/70 (44%), Gaps = 2/70 (2%) Query: 89 TKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHF 148 +++E++ +R F + G + + + + + + D DG+G +++ Sbjct: 4 SEEEIREAFRVFDKD-GNGYISAAELRHVMTNLGEKLTDEE-VDEMIREADIDGDGQVNY 61 Query: 149 EDFVVGLSIL 158 E+FV ++ Sbjct: 62 EEFVQMMTAK 71 Score = 41.6 bits (96), Expect = 3e-04, Method: Composition-based stats. Identities = 17/59 (28%), Positives = 27/59 (45%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS 193 F FD DGNG I + ++ L E++ DI+ DG + EE + +M + Sbjct: 12 FRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 70 >2KN2-A nrPDB Length = 92 Score = 72.0 bits (175), Expect = 2e-13, Method: Composition-based stats. Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 12/81 (14%) Query: 159 LRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERF 218 + E+LK AF ++D +++G I+ E+ RH L E E VE+ Sbjct: 3 MDTDAEEELKEAFKVFDKDQNGYISASEL------------RHVMINLGEKLTDEEVEQM 50 Query: 219 FQKMDRNQDGVVTIDEFLETC 239 ++ D + DG V +EF++ Sbjct: 51 IKEADLDGDGQVNYEEFVKMM 71 Score = 40.1 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 11/67 (16%), Positives = 28/67 (41%), Gaps = 2/67 (2%) Query: 89 TKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHF 148 ++EL+ ++ F + G + + + + + D DG+G +++ Sbjct: 7 AEEELKEAFKVFDKD-QNGYISASELRHVMINLGEKLTDEE-VEQMIKEADLDGDGQVNY 64 Query: 149 EDFVVGL 155 E+FV + Sbjct: 65 EEFVKMM 71 Score = 39.3 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 18/75 (24%), Positives = 32/75 (42%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSI 194 F FD D NG I + + L E+++ D++ DG + EE + +M ++ Sbjct: 15 FKVFDKDQNGYISASELRHVMINLGEKLTDEEVEQMIKEADLDGDGQVNYEEFVKMMMTV 74 Query: 195 YDMMGRHTYPILRED 209 G + + LR Sbjct: 75 RGGGGGNGWSRLRRK 89 >3E3R-A nrPDB Length = 204 Score = 72.0 bits (175), Expect = 2e-13, Method: Composition-based stats. Identities = 40/204 (19%), Positives = 75/204 (36%), Gaps = 25/204 (12%) Query: 57 PQGSDSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGF--KNECPTGLVDEDTF 114 P GS + + + + + L + + +Q L R F + + +D D F Sbjct: 9 PLGSHMDAVDATME--KLRAQCLSRGASG-------IQGLARFFRQLDRDGSRSLDADEF 59 Query: 115 KLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLY 174 + ++ D A + +D +G+G + E+F+ L + + AF Sbjct: 60 RQGLAKLGLVLDQAE-AEGVCRKWDRNGSGTLDLEEFLRALRPPMSQAREAVIAAAFAKL 118 Query: 175 DINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMD-RNQDGVVTID 233 D + DG +T +++ + H E E + RF D +DG VT+ Sbjct: 119 DRSGDGVVTVDDLRGVYSG-----RAHPKVRSGEWTEDEVLRRFLDNFDSSEKDGQVTLA 173 Query: 234 EFLE-------TCQKDENIMNSMQ 250 EF + + DE + M Sbjct: 174 EFQDYYSGVSASMNTDEEFVAMMT 197 >5E37-A nrPDB Length = 356 Score = 71.6 bits (174), Expect = 3e-13, Method: Composition-based stats. Identities = 22/89 (24%), Positives = 46/89 (51%), Gaps = 4/89 (4%) Query: 151 FVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDA 210 F + + + E L+ F + D++ +G I +EE+ +++S M Y + + Sbjct: 16 FEGLMDDASKAKMEE-LERRFKMADVDGNGHIDREELRNLLES---MESGEVYMMSQHWL 71 Query: 211 PLEHVERFFQKMDRNQDGVVTIDEFLETC 239 P + +ER ++ D N+DGV++ +EF + Sbjct: 72 PEDELERCMEQYDVNKDGVISFEEFKQII 100 Score = 66.6 bits (161), Expect = 9e-12, Method: Composition-based stats. Identities = 34/176 (19%), Positives = 66/176 (37%), Gaps = 25/176 (14%) Query: 89 TKKELQSLYRGFK--NECPTGLVDEDTFKLIYSQFFP--------QGDATTYAHFLFNAF 138 +K +++ L R FK + G +D + + + + Sbjct: 24 SKAKMEELERRFKMADVDGNGHIDREELRNLLESMESGEVYMMSQHWLPEDELERCMEQY 83 Query: 139 DADGNGAIHFEDF--VVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYD 196 D + +G I FE+F ++ +LL GT+ E + AF D + +G I E+ + S+ + Sbjct: 84 DVNKDGVISFEEFKQIIYDGLLLEGTLAE-YESAFKAVDKSGNGTIGATELSKLFASLGN 142 Query: 197 MMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQLF 252 + LE + Q D++ G + EFL + + M + Sbjct: 143 PVS------------LEKLVDLMQMYDKDDSGQIEFPEFLLMFRNSLLDLKDMTTY 186 Score = 53.2 bits (126), Expect = 1e-07, Method: Composition-based stats. Identities = 32/123 (26%), Positives = 47/123 (38%), Gaps = 4/123 (3%) Query: 88 FTKKELQSLYRGFKNECPTGLVDEDTFKLI-YSQFFPQGDATTYAHFLFNAFDADGNGAI 146 + EL+ + G++ + FK I Y +G Y F A D GNG I Sbjct: 71 LPEDELERCMEQYDVN-KDGVISFEEFKQIIYDGLLLEGTLAEY-ESAFKAVDKSGNGTI 128 Query: 147 HFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMK-SIYDMMGRHTYPI 205 + + L EKL +YD + G I E L + + S+ D+ TY Sbjct: 129 GATELSKLFASLGNPVSLEKLVDLMQMYDKDDSGQIEFPEFLLMFRNSLLDLKDMTTYMT 188 Query: 206 LRE 208 L E Sbjct: 189 LDE 191 >2RO9-A nrPDB Length = 69 Score = 70.1 bits (170), Expect = 9e-13, Method: Composition-based stats. Identities = 20/77 (25%), Positives = 36/77 (46%), Gaps = 12/77 (15%) Query: 163 VHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKM 222 E+LK AF ++D +++G I+ E+ RH L E E V+ ++ Sbjct: 2 SEEELKEAFRVFDKDQNGFISAAEL------------RHVMTNLGEKLTDEEVDEMIREA 49 Query: 223 DRNQDGVVTIDEFLETC 239 D + DG + +EF++ Sbjct: 50 DVDGDGQINYEEFVKVM 66 Score = 39.7 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 30/67 (44%), Gaps = 2/67 (2%) Query: 89 TKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHF 148 +++EL+ +R F + G + + + + + + D DG+G I++ Sbjct: 2 SEEELKEAFRVFDKD-QNGFISAAELRHVMTNLGEKLTDEE-VDEMIREADVDGDGQINY 59 Query: 149 EDFVVGL 155 E+FV + Sbjct: 60 EEFVKVM 66 Score = 39.7 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 16/59 (27%), Positives = 26/59 (44%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS 193 F FD D NG I + ++ L E++ D++ DG I EE + +M + Sbjct: 10 FRVFDKDQNGFISAAELRHVMTNLGEKLTDEEVDEMIREADVDGDGQINYEEFVKVMMA 68 >3FWC-A nrPDB Length = 161 Score = 69.7 bits (169), Expect = 1e-12, Method: Composition-based stats. Identities = 29/158 (18%), Positives = 65/158 (41%), Gaps = 16/158 (10%) Query: 85 QTKFTKKELQSLYRGF--KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADG 142 ++ +++ Q +Y F + G +D K+ + L + +D++G Sbjct: 14 NSELLEEQKQEIYEAFSLFDMNNDGFLDYHELKVAMKALGFELPKREILD-LIDEYDSEG 72 Query: 143 NGAIHFEDFVVGLSIL-LRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRH 201 + ++DF + + L+ +++K AF L+D + G I+ + + + K Sbjct: 73 RHLMKYDDFYIVMGEKILKRDPLDEIKRAFQLFDDDHTGKISIKNLRRVAKE-------- 124 Query: 202 TYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETC 239 L E E + ++ D + DG + +EF+ C Sbjct: 125 ----LGETLTDEELRAMIEEFDLDGDGEINENEFIAIC 158 >2KZ2-A nrPDB Length = 94 Score = 69.7 bits (169), Expect = 1e-12, Method: Composition-based stats. Identities = 20/84 (23%), Positives = 37/84 (44%), Gaps = 12/84 (14%) Query: 156 SILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHV 215 S++ E+++ AF + D + +G I+ E+ RH L E E V Sbjct: 20 SLMKDTDSEEEIREAFRVEDKDGNGYISAAEL------------RHVMTNLGEKLTDEEV 67 Query: 216 ERFFQKMDRNQDGVVTIDEFLETC 239 + ++ D + DG V +EF++ Sbjct: 68 DEMIREADIDGDGQVNYEEFVQMM 91 Score = 38.1 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 10/70 (14%), Positives = 32/70 (45%), Gaps = 2/70 (2%) Query: 89 TKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHF 148 +++E++ +R +++ G + + + + + + D DG+G +++ Sbjct: 27 SEEEIREAFR-VEDKDGNGYISAAELRHVMTNLGEKLTDEE-VDEMIREADIDGDGQVNY 84 Query: 149 EDFVVGLSIL 158 E+FV ++ Sbjct: 85 EEFVQMMTAK 94 Score = 38.1 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 16/59 (27%), Positives = 26/59 (44%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS 193 F D DGNG I + ++ L E++ DI+ DG + EE + +M + Sbjct: 35 FRVEDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA 93 >2ROB-A nrPDB Length = 70 Score = 68.9 bits (167), Expect = 2e-12, Method: Composition-based stats. Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 12/76 (15%) Query: 164 HEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMD 223 E+LK AF ++D +++G I+ E+ RH L E E VE+ ++ D Sbjct: 3 EEELKEAFKVFDKDQNGYISASEL------------RHVMINLGEKLTDEEVEQMIKEAD 50 Query: 224 RNQDGVVTIDEFLETC 239 + DG V +EF++ Sbjct: 51 LDGDGQVNYEEFVKMM 66 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 11/67 (16%), Positives = 28/67 (41%), Gaps = 2/67 (2%) Query: 89 TKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHF 148 ++EL+ ++ F + G + + + + + D DG+G +++ Sbjct: 2 AEEELKEAFKVFDKD-QNGYISASELRHVMINLGEKLTDEE-VEQMIKEADLDGDGQVNY 59 Query: 149 EDFVVGL 155 E+FV + Sbjct: 60 EEFVKMM 66 Score = 37.7 bits (86), Expect = 0.005, Method: Composition-based stats. Identities = 15/60 (25%), Positives = 27/60 (45%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSI 194 F FD D NG I + + L E+++ D++ DG + EE + +M ++ Sbjct: 10 FKVFDKDQNGYISASELRHVMINLGEKLTDEEVEQMIKEADLDGDGQVNYEEFVKMMMTV 69 >2M5E-A nrPDB Length = 73 Score = 68.9 bits (167), Expect = 2e-12, Method: Composition-based stats. Identities = 18/80 (22%), Positives = 33/80 (41%), Gaps = 12/80 (15%) Query: 160 RGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFF 219 E+L AF ++D + +G I+ E+ RH L E + V+ Sbjct: 3 EQDSEEELIEAFKVFDRDGNGLISAAEL------------RHVMTNLGEKLTDDEVDEMI 50 Query: 220 QKMDRNQDGVVTIDEFLETC 239 ++ D + DG + +EF+ Sbjct: 51 READIDGDGHINYEEFVRMM 70 Score = 40.8 bits (94), Expect = 6e-04, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 30/67 (44%), Gaps = 2/67 (2%) Query: 89 TKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHF 148 +++EL ++ F + GL+ + + + + + D DG+G I++ Sbjct: 6 SEEELIEAFKVFDRD-GNGLISAAELRHVMTNLGEKLTDDE-VDEMIREADIDGDGHINY 63 Query: 149 EDFVVGL 155 E+FV + Sbjct: 64 EEFVRMM 70 Score = 39.7 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 18/59 (30%), Positives = 27/59 (45%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS 193 F FD DGNG I + ++ L +++ DI+ DG I EE + +M S Sbjct: 14 FKVFDRDGNGLISAAELRHVMTNLGEKLTDDEVDEMIREADIDGDGHINYEEFVRMMVS 72 >1JC2-A nrPDB Length = 76 Score = 68.2 bits (165), Expect = 4e-12, Method: Composition-based stats. Identities = 23/81 (28%), Positives = 37/81 (45%), Gaps = 12/81 (14%) Query: 160 RGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFF 219 +G E+L F ++D N DG I EE+ I+++ E E +E Sbjct: 5 KGKSEEELANCFRIFDKNADGFIDIEELGEILRAT------------GEHVIEEDIEDLM 52 Query: 220 QKMDRNQDGVVTIDEFLETCQ 240 + D+N DG + DEFL+ + Sbjct: 53 KDSDKNNDGRIDFDEFLKMME 73 Score = 39.7 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 16/60 (26%), Positives = 26/60 (43%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSI 194 F FD + +G I E+ L + E ++ D N DG I +E L +M+ + Sbjct: 16 FRIFDKNADGFIDIEELGEILRATGEHVIEEDIEDLMKDSDKNNDGRIDFDEFLKMMEGV 75 Score = 35.8 bits (81), Expect = 0.019, Method: Composition-based stats. Identities = 12/74 (16%), Positives = 30/74 (40%), Gaps = 2/74 (2%) Query: 82 LQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDAD 141 ++ +++EL + +R F G +D + I + ++ D + Sbjct: 1 MEDAKGKSEEELANCFRIFDKNA-DGFIDIEELGEILRATGEHVIEEDIEDLMKDS-DKN 58 Query: 142 GNGAIHFEDFVVGL 155 +G I F++F+ + Sbjct: 59 NDGRIDFDEFLKMM 72 >3QRX-A nrPDB Length = 169 Score = 66.3 bits (160), Expect = 1e-11, Method: Composition-based stats. Identities = 31/132 (23%), Positives = 49/132 (37%), Gaps = 25/132 (18%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS- 193 F+ FD DG+G I ++ V + L E++K + D + G I EE L +M + Sbjct: 34 FDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMISEIDKDGSGTIDFEEFLTMMTAK 93 Query: 194 ------------------------IYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGV 229 I R L E+ E ++ + DRN D Sbjct: 94 MGERDSREEILKAFRLFDDDNSGTITIKDLRRVAKELGENLTEEELQEMIAEADRNDDNE 153 Query: 230 VTIDEFLETCQK 241 + DEF+ +K Sbjct: 154 IDEDEFIRIMKK 165 Score = 58.9 bits (141), Expect = 2e-09, Method: Composition-based stats. Identities = 20/103 (19%), Positives = 46/103 (44%), Gaps = 19/103 (18%) Query: 159 LRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERF 218 L ++++ AF+L+D + G I +E+ M++ L + E +++ Sbjct: 22 LTEEQKQEIREAFDLFDTDGSGTIDAKELKVAMRA------------LGFEPKKEEIKKM 69 Query: 219 FQKMDRNQDGVVTIDEFLETCQKD-------ENIMNSMQLFEN 254 ++D++ G + +EFL E I+ + +LF++ Sbjct: 70 ISEIDKDGSGTIDFEEFLTMMTAKMGERDSREEILKAFRLFDD 112 Score = 40.8 bits (94), Expect = 5e-04, Method: Composition-based stats. Identities = 24/105 (22%), Positives = 43/105 (40%), Gaps = 1/105 (0%) Query: 90 KKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFE 149 K+E++ + + +G +D + F + + + D+ F FD D +G I + Sbjct: 63 KEEIKKMISEIDKD-GSGTIDFEEFLTMMTAKMGERDSREEILKAFRLFDDDNSGTITIK 121 Query: 150 DFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSI 194 D L E+L+ D N D I ++E + IMK Sbjct: 122 DLRRVAKELGENLTEEELQEMIAEADRNDDNEIDEDEFIRIMKKT 166 >1OZS-A nrPDB Length = 73 Score = 65.9 bits (159), Expect = 2e-11, Method: Composition-based stats. Identities = 22/82 (26%), Positives = 38/82 (46%), Gaps = 12/82 (14%) Query: 159 LRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERF 218 ++G E+L F ++D N DG I EE+ ++++ E + +E Sbjct: 1 MKGKSEEELSDLFRMFDKNADGYIDLEELKIMLQAT------------GETITEDDIEEL 48 Query: 219 FQKMDRNQDGVVTIDEFLETCQ 240 + D+N DG + DEFLE + Sbjct: 49 MKDGDKNNDGRIDYDEFLEFMK 70 Score = 41.2 bits (95), Expect = 5e-04, Method: Composition-based stats. Identities = 17/61 (27%), Positives = 26/61 (42%) Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS 193 LF FD + +G I E+ + L + ++ D N DG I +E L MK Sbjct: 12 LFRMFDKNADGYIDLEELKIMLQATGETITEDDIEELMKDGDKNNDGRIDYDEFLEFMKG 71 Query: 194 I 194 + Sbjct: 72 V 72 Score = 32.4 bits (72), Expect = 0.21, Method: Composition-based stats. Identities = 12/67 (17%), Positives = 29/67 (43%), Gaps = 2/67 (2%) Query: 89 TKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHF 148 +++EL L+R F G +D + K++ + + D + +G I + Sbjct: 5 SEEELSDLFRMFDKNA-DGYIDLEELKIMLQATGETITEDDIEELMKDG-DKNNDGRIDY 62 Query: 149 EDFVVGL 155 ++F+ + Sbjct: 63 DEFLEFM 69 Score = 28.5 bits (62), Expect = 3.1, Method: Composition-based stats. Identities = 8/30 (26%), Positives = 14/30 (46%) Query: 212 LEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 E + F+ D+N DG + ++E Q Sbjct: 6 EEELSDLFRMFDKNADGYIDLEELKIMLQA 35 >2LV7-A nrPDB Length = 100 Score = 64.7 bits (156), Expect = 4e-11, Method: Composition-based stats. Identities = 19/72 (26%), Positives = 37/72 (51%), Gaps = 12/72 (16%) Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDR 224 E+++ AF ++D + +G I+K+E+ M+S+ M +E Q++D Sbjct: 36 EEIREAFKVFDRDGNGFISKQELGTAMRSLGYMPN------------EVELEVIIQRLDM 83 Query: 225 NQDGVVTIDEFL 236 + DG V +EF+ Sbjct: 84 DGDGQVDFEEFV 95 Score = 47.8 bits (112), Expect = 5e-06, Method: Composition-based stats. Identities = 17/83 (20%), Positives = 29/83 (34%), Gaps = 4/83 (4%) Query: 76 PEGLDQLQAQTKFTKKELQSLYRGFK--NECPTGLVDEDTFKLIYSQFFPQGDATTYAHF 133 P L + Q + EL+ + FK + G + + + Sbjct: 19 PNLLSE-QRPVDIPEDELEEIREAFKVFDRDGNGFISKQELGTAMRSLGYMPNEVEL-EV 76 Query: 134 LFNAFDADGNGAIHFEDFVVGLS 156 + D DG+G + FE+FV L Sbjct: 77 IIQRLDMDGDGQVDFEEFVTLLG 99 Score = 42.0 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 15/57 (26%), Positives = 26/57 (45%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIM 191 F FD DGNG I ++ + L +L+ D++ DG + EE + ++ Sbjct: 42 FKVFDRDGNGFISKQELGTAMRSLGYMPNEVELEVIIQRLDMDGDGQVDFEEFVTLL 98 >2LC5-A nrPDB Length = 151 Score = 63.2 bits (152), Expect = 1e-10, Method: Composition-based stats. Identities = 25/161 (15%), Positives = 63/161 (39%), Gaps = 16/161 (9%) Query: 80 DQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFD 139 +Q + T ++E + ++ F + + + + + + +D Sbjct: 3 EQKKVLTAEEQQEYKEAFQLFDKD-NDNKLTAEELGTVMRALGANPTKQKISE-IVKDYD 60 Query: 140 ADGNGAIHFEDFVVGLSILLRG-TVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMM 198 D +G E F+ + + E +K AF ++D K+G I+ E+ Sbjct: 61 KDNSGKFDQETFLTIMLEYGQEVDSTEDIKKAFEIFDKEKNGYISASEL----------- 109 Query: 199 GRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETC 239 +H L E + V+ +++ ++G++ +D+F++ Sbjct: 110 -KHVLTTLGEKLTEQEVDDLLKEIGV-EEGLINVDDFVKLI 148 >2K7C-A nrPDB Length = 72 Score = 62.4 bits (150), Expect = 2e-10, Method: Composition-based stats. Identities = 19/77 (24%), Positives = 33/77 (42%), Gaps = 11/77 (14%) Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDR 224 ++L+ AF +D N DG I+ E+ M+ + L +E + +D Sbjct: 7 KELRDAFREFDTNGDGEISTSELREAMRKL-----------LGHQVGHRDIEEIIRDVDL 55 Query: 225 NQDGVVTIDEFLETCQK 241 N DG V +EF+ + Sbjct: 56 NGDGRVDFEEFVRMMSR 72 Score = 44.7 bits (104), Expect = 4e-05, Method: Composition-based stats. Identities = 14/67 (20%), Positives = 25/67 (37%), Gaps = 1/67 (1%) Query: 91 KELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFED 150 KEL+ +R F G + + + + D +G+G + FE+ Sbjct: 7 KELRDAFREFDTN-GDGEISTSELREAMRKLLGHQVGHRDIEEIIRDVDLNGDGRVDFEE 65 Query: 151 FVVGLSI 157 FV +S Sbjct: 66 FVRMMSR 72 Score = 36.6 bits (83), Expect = 0.009, Method: Composition-based stats. Identities = 17/58 (29%), Positives = 27/58 (46%), Gaps = 1/58 (1%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTV-HEKLKWAFNLYDINKDGCITKEEMLAIM 191 F FD +G+G I + + LL V H ++ D+N DG + EE + +M Sbjct: 13 FREFDTNGDGEISTSELREAMRKLLGHQVGHRDIEEIIRDVDLNGDGRVDFEEFVRMM 70 >2B1U-A nrPDB Length = 71 Score = 62.4 bits (150), Expect = 2e-10, Method: Composition-based stats. Identities = 21/78 (26%), Positives = 35/78 (44%), Gaps = 12/78 (15%) Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDR 224 E L+ AF +D + DG IT +E+ M L + P E ++ ++ D Sbjct: 6 EDLQVAFRAFDQDGDGHITVDELRRAMAG------------LGQPLPQEELDAMIREADV 53 Query: 225 NQDGVVTIDEFLETCQKD 242 +QDG V +EF ++ Sbjct: 54 DQDGRVNYEEFARMLAQE 71 Score = 42.4 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 16/60 (26%), Positives = 29/60 (48%) Query: 132 HFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIM 191 F AFD DG+G I ++ ++ L + E+L D+++DG + EE ++ Sbjct: 9 QVAFRAFDQDGDGHITVDELRRAMAGLGQPLPQEELDAMIREADVDQDGRVNYEEFARML 68 Score = 40.8 bits (94), Expect = 5e-04, Method: Composition-based stats. Identities = 13/66 (19%), Positives = 27/66 (40%), Gaps = 2/66 (3%) Query: 91 KELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFED 150 ++LQ +R F + G + D + + Q + D D +G +++E+ Sbjct: 6 EDLQVAFRAFDQD-GDGHITVDELRRAMAGLG-QPLPQEELDAMIREADVDQDGRVNYEE 63 Query: 151 FVVGLS 156 F L+ Sbjct: 64 FARMLA 69 Score = 28.1 bits (61), Expect = 3.5, Method: Composition-based stats. Identities = 9/28 (32%), Positives = 16/28 (57%) Query: 212 LEHVERFFQKMDRNQDGVVTIDEFLETC 239 LE ++ F+ D++ DG +T+DE Sbjct: 5 LEDLQVAFRAFDQDGDGHITVDELRRAM 32 >3KF9-A nrPDB Length = 149 Score = 62.4 bits (150), Expect = 2e-10, Method: Composition-based stats. Identities = 30/132 (22%), Positives = 48/132 (36%), Gaps = 25/132 (18%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS- 193 F+ FD DG+G I ++ V + L E++K D + G I EE L +M + Sbjct: 14 FDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMIADIDKDGSGTIDFEEFLQMMTAK 73 Query: 194 ------------------------IYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGV 229 I + L E+ E ++ + DR+ DG Sbjct: 74 MGERDSREEIMKAFRLFDDDETGKISFKNLKRVAKELGENMTDEELQEMIDEADRDGDGE 133 Query: 230 VTIDEFLETCQK 241 V +EF +K Sbjct: 134 VNEEEFFRIMKK 145 Score = 57.0 bits (136), Expect = 8e-09, Method: Composition-based stats. Identities = 21/103 (20%), Positives = 46/103 (44%), Gaps = 19/103 (18%) Query: 159 LRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERF 218 L ++++ AF+L+D + G I +E+ M++ L + E +++ Sbjct: 2 LTEEQKQEIREAFDLFDTDGSGTIDAKELKVAMRA------------LGFEPKKEEIKKM 49 Query: 219 FQKMDRNQDGVVTIDEFLETCQKD-------ENIMNSMQLFEN 254 +D++ G + +EFL+ E IM + +LF++ Sbjct: 50 IADIDKDGSGTIDFEEFLQMMTAKMGERDSREEIMKAFRLFDD 92 Score = 44.3 bits (103), Expect = 5e-05, Method: Composition-based stats. Identities = 22/93 (23%), Positives = 39/93 (41%) Query: 102 NECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRG 161 ++ +G +D + F + + + D+ F FD D G I F++ L Sbjct: 54 DKDGSGTIDFEEFLQMMTAKMGERDSREEIMKAFRLFDDDETGKISFKNLKRVAKELGEN 113 Query: 162 TVHEKLKWAFNLYDINKDGCITKEEMLAIMKSI 194 E+L+ + D + DG + +EE IMK Sbjct: 114 MTDEELQEMIDEADRDGDGEVNEEEFFRIMKKT 146 >2M97-A nrPDB Length = 69 Score = 62.0 bits (149), Expect = 3e-10, Method: Composition-based stats. Identities = 19/78 (24%), Positives = 35/78 (44%), Gaps = 12/78 (15%) Query: 163 VHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKM 222 E+L F ++D + +G I +EE I++ + E E V+ F Sbjct: 1 SEEELSECFRIFDKDGNGFIDREEFGDIIR------------LTGEQLTDEDVDEIFGDS 48 Query: 223 DRNQDGVVTIDEFLETCQ 240 D +++G + DEFL+ + Sbjct: 49 DTDKNGRIDFDEFLKMME 66 Score = 43.5 bits (101), Expect = 9e-05, Method: Composition-based stats. Identities = 19/60 (31%), Positives = 30/60 (50%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSI 194 F FD DGNG I E+F + + E + F D +K+G I +E L +M+++ Sbjct: 9 FRIFDKDGNGFIDREEFGDIIRLTGEQLTDEDVDEIFGDSDTDKNGRIDFDEFLKMMENV 68 Score = 42.8 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 29/67 (43%), Gaps = 2/67 (2%) Query: 89 TKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHF 148 +++EL +R F + G +D + F I Q +F D D NG I F Sbjct: 1 SEEELSECFRIFDKD-GNGFIDREEFGDIIRLTGEQLTDED-VDEIFGDSDTDKNGRIDF 58 Query: 149 EDFVVGL 155 ++F+ + Sbjct: 59 DEFLKMM 65 >5H7D-E nrPDB Length = 120 Score = 62.0 bits (149), Expect = 3e-10, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 36/77 (46%), Gaps = 12/77 (15%) Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDR 224 + K AF+L+D + DG IT +E+ +M+S L ++ ++ ++D Sbjct: 56 QAFKEAFSLFDKDGDGTITTKELGTVMRS------------LGQNPTEAELQDMINEVDA 103 Query: 225 NQDGVVTIDEFLETCQK 241 + +G + EFL + Sbjct: 104 DGNGTIDFPEFLTMMAR 120 Score = 52.4 bits (124), Expect = 2e-07, Method: Composition-based stats. Identities = 18/99 (18%), Positives = 35/99 (35%), Gaps = 10/99 (10%) Query: 59 GSDSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIY 118 S D + + + + + L+Q+QA + + F + G + + Sbjct: 32 ISSLLDDPSQSANLLAEAKKLNQIQA--------FKEAFSLFDKD-GDGTITTKELGTVM 82 Query: 119 SQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSI 157 + N DADGNG I F +F+ ++ Sbjct: 83 RSLGQNPTEAELQD-MINEVDADGNGTIDFPEFLTMMAR 120 Score = 42.0 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 16/57 (28%), Positives = 27/57 (47%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIM 191 F+ FD DG+G I ++ + L + +L+ N D + +G I E L +M Sbjct: 62 FSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMM 118 >5OTJ-D nrPDB Length = 110 Score = 61.2 bits (147), Expect = 4e-10, Method: Composition-based stats. Identities = 16/83 (19%), Positives = 36/83 (43%), Gaps = 13/83 (15%) Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDR 224 + ++ F +D N DG I+ E+ ++++ + V+R ++D Sbjct: 3 DDMERIFKRFDTNGDGKISLSELTDALRTLG-------------STSADEVQRMMAEIDT 49 Query: 225 NQDGVVTIDEFLETCQKDENIMN 247 + DG + +EF+ C + +M Sbjct: 50 DGDGFIDFNEFISFCNANPGLMK 72 Score = 42.8 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 9/64 (14%), Positives = 21/64 (32%), Gaps = 3/64 (4%) Query: 90 KKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFE 149 +++ +++ F G + + + D DG+G I F Sbjct: 2 ADDMERIFKRFDTN-GDGKISLSELTDALRTLG--STSADEVQRMMAEIDTDGDGFIDFN 58 Query: 150 DFVV 153 +F+ Sbjct: 59 EFIS 62 Score = 42.4 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 29/77 (37%), Gaps = 1/77 (1%) Query: 132 HFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIM 191 +F FD +G+G I + L L T ++++ D + DG I E ++ Sbjct: 6 ERIFKRFDTNGDGKISLSELTDAL-RTLGSTSADEVQRMMAEIDTDGDGFIDFNEFISFC 64 Query: 192 KSIYDMMGRHTYPILRE 208 + +M E Sbjct: 65 NANPGLMKDVAKVFKGE 81 >5COC-A nrPDB Length = 130 Score = 60.9 bits (146), Expect = 5e-10, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 36/77 (46%), Gaps = 12/77 (15%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRN 225 + K AF+L+D + DG IT +E+ +M+S L ++ ++ ++D + Sbjct: 64 EFKEAFSLFDKDGDGTITTKELGTVMRS------------LGQNPTEAELQDMINEVDAD 111 Query: 226 QDGVVTIDEFLETCQKD 242 +G + EFL + Sbjct: 112 GNGTIDFPEFLTMMARK 128 Score = 56.6 bits (135), Expect = 1e-08, Method: Composition-based stats. Identities = 17/102 (16%), Positives = 36/102 (35%), Gaps = 2/102 (1%) Query: 59 GSDSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIY 118 D + + + + + L+ QA + E + + F + G + + Sbjct: 31 IQSLKDDPSQSANLLAEAKCLNDAQAAAEECIAEFKEAFSLFDKD-GDGTITTKELGTVM 89 Query: 119 SQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLR 160 + N DADGNG I F +F+ ++ ++ Sbjct: 90 RSLGQNPTEAELQD-MINEVDADGNGTIDFPEFLTMMARKMK 130 Score = 40.8 bits (94), Expect = 5e-04, Method: Composition-based stats. Identities = 16/57 (28%), Positives = 27/57 (47%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIM 191 F+ FD DG+G I ++ + L + +L+ N D + +G I E L +M Sbjct: 69 FSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMM 125 >4WPX-A nrPDB Length = 177 Score = 60.9 bits (146), Expect = 5e-10, Method: Composition-based stats. Identities = 29/189 (15%), Positives = 66/189 (34%), Gaps = 26/189 (13%) Query: 69 LSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFK--NECPTGLVDEDTFKLIYSQFFPQGD 126 ++ R + + K + ++ + F+ + GL+ + F+ + Sbjct: 1 MAATRQIQYTIPPREDYNKLSDEQKTRISEAFELFDSNKDGLLSYEEFRFVLRALGFDLP 60 Query: 127 ATTYAHFLFNAFDADGNGAIH------FEDFVVGLSILLRGTV------HEKLKWAFNLY 174 L N + F + + L GT+ ++L+ AF L+ Sbjct: 61 KQQTYDMLVRHGQRPANWPHDQECPPVYRQFNLATAQALAGTLIRQRDPRDELRRAFRLF 120 Query: 175 DINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDE 234 D++ G IT++++ + + + + P ++ ++ D N G V DE Sbjct: 121 DVDGKGMITEDDLRKVCQQV------------GNNIPDADIQAMIEEFDSNGKGGVDEDE 168 Query: 235 FLETCQKDE 243 FL + Sbjct: 169 FLRLMMSKK 177 >2KSZ-A nrPDB Length = 76 Score = 60.5 bits (145), Expect = 7e-10, Method: Composition-based stats. Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 12/77 (15%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRN 225 K AF L+D + DGCIT EE+ +++S L ++ E ++ ++D + Sbjct: 11 DFKEAFGLFDKDGDGCITVEELATVIRS------------LDQNPTEEELQDMISEVDAD 58 Query: 226 QDGVVTIDEFLETCQKD 242 +G + DEFL K Sbjct: 59 GNGTIEFDEFLSLMAKK 75 Score = 40.1 bits (92), Expect = 9e-04, Method: Composition-based stats. Identities = 11/74 (14%), Positives = 29/74 (39%), Gaps = 3/74 (4%) Query: 88 FTKKELQSLYRGF--KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGA 145 +++++ F ++ G + + + + + DADGNG Sbjct: 4 LSEEQIVDFKEAFGLFDKDGDGCITVEELATVIRSLDQNPTEEELQD-MISEVDADGNGT 62 Query: 146 IHFEDFVVGLSILL 159 I F++F+ ++ + Sbjct: 63 IEFDEFLSLMAKKV 76 Score = 39.7 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 17/57 (29%), Positives = 29/57 (50%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIM 191 F FD DG+G I E+ + L + E+L+ + D + +G I +E L++M Sbjct: 16 FGLFDKDGDGCITVEELATVIRSLDQNPTEEELQDMISEVDADGNGTIEFDEFLSLM 72 >3IFK-A nrPDB Length = 90 Score = 60.1 bits (144), Expect = 1e-09, Method: Composition-based stats. Identities = 17/88 (19%), Positives = 35/88 (39%), Gaps = 4/88 (4%) Query: 88 FTKKELQSLYRGF--KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGA 145 T++++ F ++ G + + + N DADGNG Sbjct: 4 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQD-MINEVDADGNGT 62 Query: 146 IHFEDFVVGLSILLRGT-VHEKLKWAFN 172 I F +F+ ++ ++ T E+++ AF Sbjct: 63 IDFPEFLTMMARKMKDTDSEEEIREAFR 90 Score = 55.9 bits (133), Expect = 2e-08, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 36/77 (46%), Gaps = 12/77 (15%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRN 225 + K AF+L+D + DG IT +E+ +M+S L ++ ++ ++D + Sbjct: 11 EFKEAFSLFDKDGDGTITTKELGTVMRS------------LGQNPTEAELQDMINEVDAD 58 Query: 226 QDGVVTIDEFLETCQKD 242 +G + EFL + Sbjct: 59 GNGTIDFPEFLTMMARK 75 Score = 38.5 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 16/72 (22%), Positives = 27/72 (37%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSI 194 F+ FD DG+G I ++ + L + +L+ N D + +G I E L +M Sbjct: 16 FSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARK 75 Query: 195 YDMMGRHTYPIL 206 Sbjct: 76 MKDTDSEEEIRE 87 >2K2A-A nrPDB Length = 70 Score = 59.7 bits (143), Expect = 1e-09, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 33/77 (42%), Gaps = 12/77 (15%) Query: 163 VHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKM 222 + ++L+ AF LYD +G I+ + M I+ L E E ++ ++ Sbjct: 1 MQQELREAFRLYDKEGNGYISTDVMREILAE------------LDETLSSEDLDAMIDEI 48 Query: 223 DRNQDGVVTIDEFLETC 239 D + G V +EF+ Sbjct: 49 DADGSGTVDFEEFMGVM 65 Score = 42.0 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 33/67 (49%), Gaps = 2/67 (2%) Query: 90 KKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFE 149 ++EL+ +R + E G + D + I ++ + + + DADG+G + FE Sbjct: 2 QQELREAFRLYDKE-GNGYISTDVMREILAELDETLSSEDL-DAMIDEIDADGSGTVDFE 59 Query: 150 DFVVGLS 156 +F+ ++ Sbjct: 60 EFMGVMT 66 Score = 29.3 bits (64), Expect = 1.6, Method: Composition-based stats. Identities = 15/57 (26%), Positives = 24/57 (42%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIM 191 F +D +GNG I + L+ L E L + D + G + EE + +M Sbjct: 9 FRLYDKEGNGYISTDVMREILAELDETLSSEDLDAMIDEIDADGSGTVDFEEFMGVM 65 >2LVK-A nrPDB Length = 77 Score = 59.7 bits (143), Expect = 1e-09, Method: Composition-based stats. Identities = 16/83 (19%), Positives = 36/83 (43%), Gaps = 13/83 (15%) Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDR 224 + ++ F +D N DG I+ E+ ++++ + V+R ++D Sbjct: 2 DDMERIFKRFDTNGDGKISLSELTDALRTLG-------------STSADEVQRMMAEIDT 48 Query: 225 NQDGVVTIDEFLETCQKDENIMN 247 + DG + +EF+ C + +M Sbjct: 49 DGDGFIDFNEFISFCNANPGLMK 71 Score = 41.2 bits (95), Expect = 4e-04, Method: Composition-based stats. Identities = 9/64 (14%), Positives = 21/64 (32%), Gaps = 3/64 (4%) Query: 90 KKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFE 149 +++ +++ F G + + + D DG+G I F Sbjct: 1 ADDMERIFKRFDTN-GDGKISLSELTDALRTLG--STSADEVQRMMAEIDTDGDGFIDFN 57 Query: 150 DFVV 153 +F+ Sbjct: 58 EFIS 61 Score = 40.8 bits (94), Expect = 5e-04, Method: Composition-based stats. Identities = 15/68 (22%), Positives = 28/68 (41%), Gaps = 1/68 (1%) Query: 132 HFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIM 191 +F FD +G+G I + L L T ++++ D + DG I E ++ Sbjct: 5 ERIFKRFDTNGDGKISLSELTDAL-RTLGSTSADEVQRMMAEIDTDGDGFIDFNEFISFC 63 Query: 192 KSIYDMMG 199 + +M Sbjct: 64 NANPGLMK 71 >4Q57-A nrPDB Length = 65 Score = 58.9 bits (141), Expect = 2e-09, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 35/74 (47%), Gaps = 12/74 (16%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRN 225 + K AF+L+D + DG IT +E+ +M+S L ++ ++ ++D + Sbjct: 3 EFKEAFSLFDKDGDGTITTKELGTVMRS------------LGQNPTEAELQDMINEVDAD 50 Query: 226 QDGVVTIDEFLETC 239 +G + EFL Sbjct: 51 GNGTIDFPEFLTMM 64 Score = 49.7 bits (117), Expect = 1e-06, Method: Composition-based stats. Identities = 13/65 (20%), Positives = 23/65 (35%), Gaps = 2/65 (3%) Query: 92 ELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDF 151 E + + F + G + + + N DADGNG I F +F Sbjct: 3 EFKEAFSLFDKD-GDGTITTKELGTVMRSLGQNPTEAELQD-MINEVDADGNGTIDFPEF 60 Query: 152 VVGLS 156 + ++ Sbjct: 61 LTMMA 65 Score = 40.4 bits (93), Expect = 8e-04, Method: Composition-based stats. Identities = 16/57 (28%), Positives = 27/57 (47%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIM 191 F+ FD DG+G I ++ + L + +L+ N D + +G I E L +M Sbjct: 8 FSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMM 64 >2I08-A nrPDB Length = 78 Score = 58.5 bits (140), Expect = 3e-09, Method: Composition-based stats. Identities = 19/76 (25%), Positives = 35/76 (46%), Gaps = 12/76 (15%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRN 225 + K AF+LYD + DG IT +E+ +M+S L + ++ ++D + Sbjct: 11 EFKEAFSLYDKDGDGTITTKELGTVMRS------------LGLNPTEAELQDMINEVDAD 58 Query: 226 QDGVVTIDEFLETCQK 241 +G + EFL + Sbjct: 59 GNGTIDFPEFLTMMAR 74 Score = 53.9 bits (128), Expect = 6e-08, Method: Composition-based stats. Identities = 13/75 (17%), Positives = 29/75 (38%), Gaps = 3/75 (4%) Query: 88 FTKKELQSLYRGFK--NECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGA 145 T++++ F ++ G + + + N DADGNG Sbjct: 4 LTEEQIAEFKEAFSLYDKDGDGTITTKELGTVMRSLGLNPTEAELQD-MINEVDADGNGT 62 Query: 146 IHFEDFVVGLSILLR 160 I F +F+ ++ +++ Sbjct: 63 IDFPEFLTMMARIMK 77 Score = 37.4 bits (85), Expect = 0.006, Method: Composition-based stats. Identities = 16/62 (25%), Positives = 27/62 (43%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSI 194 F+ +D DG+G I ++ + L +L+ N D + +G I E L +M I Sbjct: 16 FSLYDKDGDGTITTKELGTVMRSLGLNPTEAELQDMINEVDADGNGTIDFPEFLTMMARI 75 Query: 195 YD 196 Sbjct: 76 MK 77 >2RO8-A nrPDB Length = 79 Score = 58.2 bits (139), Expect = 3e-09, Method: Composition-based stats. Identities = 19/77 (24%), Positives = 37/77 (48%), Gaps = 12/77 (15%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRN 225 + K AF+L+D + DGCIT +E+ +M+S L ++ ++ ++D + Sbjct: 11 EFKEAFSLFDKDGDGCITTKELGTVMRS------------LGQNPTEAELQDMINEVDAD 58 Query: 226 QDGVVTIDEFLETCQKD 242 +G + EFL + Sbjct: 59 GNGTIDFPEFLNLMARK 75 Score = 51.6 bits (122), Expect = 3e-07, Method: Composition-based stats. Identities = 14/77 (18%), Positives = 28/77 (36%), Gaps = 3/77 (3%) Query: 88 FTKKELQSLYRGF--KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGA 145 T +++ F ++ G + + + N DADGNG Sbjct: 4 LTDEQISEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQD-MINEVDADGNGT 62 Query: 146 IHFEDFVVGLSILLRGT 162 I F +F+ ++ ++ T Sbjct: 63 IDFPEFLNLMARKMKDT 79 Score = 37.7 bits (86), Expect = 0.005, Method: Composition-based stats. Identities = 16/57 (28%), Positives = 27/57 (47%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIM 191 F+ FD DG+G I ++ + L + +L+ N D + +G I E L +M Sbjct: 16 FSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLNLM 72 >4ZCV-A nrPDB Length = 165 Score = 57.8 bits (138), Expect = 5e-09, Method: Composition-based stats. Identities = 26/143 (18%), Positives = 48/143 (33%), Gaps = 18/143 (12%) Query: 101 KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLR 160 + G+VD + +F D + +G + FE+F+ L Sbjct: 22 LDRNGDGVVDIGELQEGLRNLGIPLGQDA-EEKIFTTGDVNKDGKLDFEEFMKYL----- 75 Query: 161 GTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQ 220 +K+K AF D N DG I E++ ++ L + E Q Sbjct: 76 KDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQ------------TLGLTISEQQAELILQ 123 Query: 221 KMDRNQDGVVTIDEFLETCQKDE 243 +D + V +E+ + + Sbjct: 124 SIDVDGTMTVDWNEWRDYFLFNP 146 Score = 48.1 bits (113), Expect = 3e-06, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 33/81 (40%), Gaps = 12/81 (14%) Query: 168 KWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQD 227 + F D N DG + E+ ++++ +G+ E+ F D N+D Sbjct: 16 ETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAE------------EKIFTTGDVNKD 63 Query: 228 GVVTIDEFLETCQKDENIMNS 248 G + +EF++ + E M Sbjct: 64 GKLDFEEFMKYLKDHEKKMKL 84 >4N5X-A nrPDB Length = 199 Score = 57.4 bits (137), Expect = 5e-09, Method: Composition-based stats. Identities = 26/143 (18%), Positives = 48/143 (33%), Gaps = 18/143 (12%) Query: 101 KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLR 160 + G+VD + +F D + +G + FE+F+ L Sbjct: 31 LDRNGDGVVDIGELQEGLRNLGIPLGQDA-EEKIFTTGDVNKDGKLDFEEFMKYL----- 84 Query: 161 GTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQ 220 +K+K AF D N DG I E++ ++ L + E Q Sbjct: 85 KDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQ------------TLGLTISEQQAELILQ 132 Query: 221 KMDRNQDGVVTIDEFLETCQKDE 243 +D + V +E+ + + Sbjct: 133 SIDVDGTMTVDWNEWRDYFLFNP 155 Score = 50.1 bits (118), Expect = 1e-06, Method: Composition-based stats. Identities = 20/101 (19%), Positives = 39/101 (38%), Gaps = 12/101 (11%) Query: 148 FEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILR 207 DFV+ + + + F D N DG + E+ ++++ +G+ Sbjct: 5 LRDFVLPTAASQDAEQPTRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAE---- 60 Query: 208 EDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNS 248 E+ F D N+DG + +EF++ + E M Sbjct: 61 --------EKIFTTGDVNKDGKLDFEEFMKYLKDHEKKMKL 93 >2AMI-A nrPDB Length = 96 Score = 57.4 bits (137), Expect = 5e-09, Method: Composition-based stats. Identities = 16/81 (19%), Positives = 37/81 (45%), Gaps = 12/81 (14%) Query: 159 LRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERF 218 L ++++ AF+L+D + G I +E+ M++ L + E +++ Sbjct: 24 LTEEQKQEIREAFDLFDTDGSGTIDAKELKVAMRA------------LGFEPKKEEIKKM 71 Query: 219 FQKMDRNQDGVVTIDEFLETC 239 ++D++ G + +EFL Sbjct: 72 ISEIDKDGSGTIDFEEFLTMM 92 Score = 55.9 bits (133), Expect = 2e-08, Method: Composition-based stats. Identities = 16/82 (19%), Positives = 35/82 (42%), Gaps = 3/82 (3%) Query: 80 DQLQAQTKFTKKELQSLYRGFK--NECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNA 137 DQ + + T+++ Q + F + +G +D K+ + + + Sbjct: 16 DQKKGRVGLTEEQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIK-KMISE 74 Query: 138 FDADGNGAIHFEDFVVGLSILL 159 D DG+G I FE+F+ ++ + Sbjct: 75 IDKDGSGTIDFEEFLTMMTAKM 96 Score = 45.5 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 18/59 (30%), Positives = 29/59 (49%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS 193 F+ FD DG+G I ++ V + L E++K + D + G I EE L +M + Sbjct: 36 FDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMISEIDKDGSGTIDFEEFLTMMTA 94 >3AAJ-A nrPDB Length = 167 Score = 56.6 bits (135), Expect = 1e-08, Method: Composition-based stats. Identities = 20/152 (13%), Positives = 51/152 (33%), Gaps = 20/152 (13%) Query: 102 NECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRG 161 ++ +G++ + + S + + FD + ++F +F + Sbjct: 14 DKDRSGVISDTELQQALSNGTWTPFNPVTVRSIISMFDRENKAGVNFSEFTGVWKYIT-- 71 Query: 162 TVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQK 221 + F YD + G I K E+ + + + +K Sbjct: 72 ----DWQNVFRTYDRDNSGMIDKNELKQALSGYR--------------LSDQFHDILIRK 113 Query: 222 MDRNQDGVVTIDEFLETCQKDENIMNSMQLFE 253 DR G + D+F++ C + + + + ++ Sbjct: 114 FDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYD 145 Score = 51.6 bits (122), Expect = 3e-07, Method: Composition-based stats. Identities = 28/103 (27%), Positives = 53/103 (51%), Gaps = 12/103 (11%) Query: 94 QSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVV 153 Q+++R + + +G++D++ K S + + + L FD G G I F+DF+ Sbjct: 74 QNVFRTYDRD-NSGMIDKNELKQALSGYRL---SDQFHDILIRKFDRQGRGQIAFDDFIQ 129 Query: 154 GLSILLRGTVHEKLKWAFNLYDINKDGCI--TKEEMLAIMKSI 194 G +L ++L F YD ++DG I + E+ L+++ SI Sbjct: 130 GCIVL------QRLTDIFRRYDTDQDGWIQVSYEQYLSMVFSI 166 Score = 27.0 bits (58), Expect = 9.0, Method: Composition-based stats. Identities = 14/89 (15%), Positives = 29/89 (32%), Gaps = 19/89 (21%) Query: 171 FNLYDINKDGCITKEEMLAIM-------------KSIYDMMGRHTYPILREDA------P 211 F D ++ G I+ E+ + +SI M R + Sbjct: 10 FQRVDKDRSGVISDTELQQALSNGTWTPFNPVTVRSIISMFDRENKAGVNFSEFTGVWKY 69 Query: 212 LEHVERFFQKMDRNQDGVVTIDEFLETCQ 240 + + F+ DR+ G++ +E + Sbjct: 70 ITDWQNVFRTYDRDNSGMIDKNELKQALS 98 >1C7W-A nrPDB Length = 81 Score = 56.2 bits (134), Expect = 1e-08, Method: Composition-based stats. Identities = 23/89 (25%), Positives = 41/89 (46%), Gaps = 11/89 (12%) Query: 159 LRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERF 218 +R E++ AF ++D N DG I +E IM+ + E VE Sbjct: 2 VRQDDEEEILRAFKVFDANGDGVIDFDEFKFIMQKVG-----------EEPLTDAEVEEA 50 Query: 219 FQKMDRNQDGVVTIDEFLETCQKDENIMN 247 ++ D + +GV+ I EF++ +K +N + Sbjct: 51 MKEADEDGNGVIDIPEFMDLIKKSKNALK 79 Score = 43.9 bits (102), Expect = 7e-05, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 32/69 (46%), Gaps = 1/69 (1%) Query: 133 FLFNAFDADGNGAIHFEDFVVGLSILLRGTV-HEKLKWAFNLYDINKDGCITKEEMLAIM 191 F FDA+G+G I F++F + + + +++ A D + +G I E + ++ Sbjct: 12 RAFKVFDANGDGVIDFDEFKFIMQKVGEEPLTDAEVEEAMKEADEDGNGVIDIPEFMDLI 71 Query: 192 KSIYDMMGR 200 K + + Sbjct: 72 KKSKNALKE 80 Score = 39.7 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 27/67 (40%), Gaps = 1/67 (1%) Query: 89 TKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHF 148 ++E+ ++ F G++D D FK I + + D DGNG I Sbjct: 6 DEEEILRAFKVFDAN-GDGVIDFDEFKFIMQKVGEEPLTDAEVEEAMKEADEDGNGVIDI 64 Query: 149 EDFVVGL 155 +F+ + Sbjct: 65 PEFMDLI 71 >4YGB-B nrPDB Length = 104 Score = 56.2 bits (134), Expect = 1e-08, Method: Composition-based stats. Identities = 17/89 (19%), Positives = 40/89 (44%), Gaps = 1/89 (1%) Query: 152 VVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAP 211 + G +L +L + F ++D + + + E+ + ++ G P++ ED Sbjct: 17 IEGRHMLEMSPQELQLHY-FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDEL 75 Query: 212 LEHVERFFQKMDRNQDGVVTIDEFLETCQ 240 + ++ + D+N DG + EF ++ Q Sbjct: 76 INIIDGVLRDDDKNNDGYIDYAEFAKSLQ 104 Score = 27.3 bits (59), Expect = 7.3, Method: Composition-based stats. Identities = 13/80 (16%), Positives = 26/80 (32%), Gaps = 11/80 (13%) Query: 87 KFTKKELQSLYRGFKNECPTGLVDEDTFKL----IYSQFFPQGDATTYAHFLFNAFD--- 139 + + +ELQ Y + L+D ++ + + L N D Sbjct: 24 EMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVL 83 Query: 140 ----ADGNGAIHFEDFVVGL 155 + +G I + +F L Sbjct: 84 RDDDKNNDGYIDYAEFAKSL 103 >3LCP-C nrPDB Length = 93 Score = 55.9 bits (133), Expect = 2e-08, Method: Composition-based stats. Identities = 15/79 (18%), Positives = 36/79 (45%), Gaps = 1/79 (1%) Query: 162 TVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQK 221 +L + F ++D + + + E+ + ++ G P++ ED + ++ + Sbjct: 16 PQELQLHY-FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRD 74 Query: 222 MDRNQDGVVTIDEFLETCQ 240 D+N DG + EF ++ Q Sbjct: 75 DDKNNDGYIDYAEFAKSLQ 93 Score = 28.5 bits (62), Expect = 2.9, Method: Composition-based stats. Identities = 13/84 (15%), Positives = 28/84 (33%), Gaps = 11/84 (13%) Query: 83 QAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKL----IYSQFFPQGDATTYAHFLFNAF 138 + + + + +ELQ Y + L+D ++ + + L N Sbjct: 9 KPEAEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINII 68 Query: 139 D-------ADGNGAIHFEDFVVGL 155 D + +G I + +F L Sbjct: 69 DGVLRDDDKNNDGYIDYAEFAKSL 92 >1M39-A nrPDB Length = 89 Score = 55.9 bits (133), Expect = 2e-08, Method: Composition-based stats. Identities = 23/96 (23%), Positives = 44/96 (45%), Gaps = 13/96 (13%) Query: 147 HFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPI 205 +F DF+ ++ + E++ AF L+D ++ G I+ + + + K Sbjct: 2 NFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKE------------ 49 Query: 206 LREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 L E+ E ++ + DR+ DG V+ EFL +K Sbjct: 50 LGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKK 85 Score = 37.4 bits (85), Expect = 0.007, Method: Composition-based stats. Identities = 21/82 (25%), Positives = 34/82 (41%) Query: 113 TFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFN 172 F + +Q + D F FD D G I F++ L E+L+ + Sbjct: 5 DFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMID 64 Query: 173 LYDINKDGCITKEEMLAIMKSI 194 D + DG ++++E L IMK Sbjct: 65 EADRDGDGEVSEQEFLRIMKKT 86 >2VRG-A nrPDB Length = 124 Score = 55.9 bits (133), Expect = 2e-08, Method: Composition-based stats. Identities = 15/79 (18%), Positives = 36/79 (45%), Gaps = 1/79 (1%) Query: 162 TVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQK 221 +L + F ++D + + + E+ + ++ G P++ ED + ++ + Sbjct: 47 PQELQLHY-FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRD 105 Query: 222 MDRNQDGVVTIDEFLETCQ 240 D+N DG + EF ++ Q Sbjct: 106 DDKNNDGYIDYAEFAKSLQ 124 Score = 28.5 bits (62), Expect = 3.3, Method: Composition-based stats. Identities = 13/84 (15%), Positives = 28/84 (33%), Gaps = 11/84 (13%) Query: 83 QAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKL----IYSQFFPQGDATTYAHFLFNAF 138 + + + + +ELQ Y + L+D ++ + + L N Sbjct: 40 KPEAEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINII 99 Query: 139 D-------ADGNGAIHFEDFVVGL 155 D + +G I + +F L Sbjct: 100 DGVLRDDDKNNDGYIDYAEFAKSL 123 >3A4U-B nrPDB Length = 143 Score = 55.5 bits (132), Expect = 2e-08, Method: Composition-based stats. Identities = 15/79 (18%), Positives = 36/79 (45%), Gaps = 1/79 (1%) Query: 162 TVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQK 221 +L + F ++D + + + E+ + ++ G P++ ED + ++ + Sbjct: 66 PQELQLHY-FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRD 124 Query: 222 MDRNQDGVVTIDEFLETCQ 240 D+N DG + EF ++ Q Sbjct: 125 DDKNNDGYIDYAEFAKSLQ 143 Score = 28.1 bits (61), Expect = 3.9, Method: Composition-based stats. Identities = 13/84 (15%), Positives = 28/84 (33%), Gaps = 11/84 (13%) Query: 83 QAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKL----IYSQFFPQGDATTYAHFLFNAF 138 + + + + +ELQ Y + L+D ++ + + L N Sbjct: 59 KPEAEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINII 118 Query: 139 D-------ADGNGAIHFEDFVVGL 155 D + +G I + +F L Sbjct: 119 DGVLRDDDKNNDGYIDYAEFAKSL 142 >2G9B-A nrPDB Length = 263 Score = 55.5 bits (132), Expect = 2e-08, Method: Composition-based stats. Identities = 23/139 (16%), Positives = 53/139 (38%), Gaps = 21/139 (15%) Query: 80 DQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDAT-------TYAH 132 QL++ +F K +R + + +G ++ + K + + T Y Sbjct: 97 QQLKSCEEFMKT-----WRKYDTDH-SGFIETEELKNFLKDLLEKANKTVDDTKLAEYTD 150 Query: 133 FLFNAFDADGNGAIHFEDFVVGLSILLR--------GTVHEKLKWAFNLYDINKDGCITK 184 + FD++ +G + + L + ++ AF LYD + +G I + Sbjct: 151 LMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDE 210 Query: 185 EEMLAIMKSIYDMMGRHTY 203 E+ A++K + + + Sbjct: 211 NELDALLKDLCEKNKQELD 229 Score = 49.7 bits (117), Expect = 1e-06, Method: Composition-based stats. Identities = 19/102 (18%), Positives = 37/102 (36%), Gaps = 4/102 (3%) Query: 149 EDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILRE 208 E+ + L + E+ + YD + G I EE+ +K + + + + Sbjct: 87 EENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTV----DD 142 Query: 209 DAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQ 250 E+ + + D N DG + + E EN + Q Sbjct: 143 TKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQ 184 Score = 45.8 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 22/107 (20%), Positives = 40/107 (37%), Gaps = 12/107 (11%) Query: 136 NAFDADGNGAIHFED---FVVGLSILLRGTVHE-KLKWA----FNLYDINKDGCITKEEM 187 +D D +G I E+ F+ L TV + KL L+D N DG + EM Sbjct: 110 RKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEM 169 Query: 188 LAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDE 234 ++ + + + F+ D++ +G + +E Sbjct: 170 ARLL----PVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENE 212 >3J04-B nrPDB Length = 143 Score = 55.1 bits (131), Expect = 3e-08, Method: Composition-based stats. Identities = 24/156 (15%), Positives = 54/156 (34%), Gaps = 20/156 (12%) Query: 88 FTKKELQSLYRGFKNECPT--GLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGA 145 F + ++Q F G +D++ + + Y + + G Sbjct: 1 FDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASMGKNPTDE-YLEGMMSE----APGP 55 Query: 146 IHFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYP 204 I+F F+ L GT + ++ AF +D G I ++ + ++ ++ D Sbjct: 56 INFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEASGFIHEDHLRELLTTMGDRF------ 109 Query: 205 ILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQ 240 E V+ +++ ++ G EF + Sbjct: 110 ------TDEEVDEMYREAPIDKKGNFNYVEFTRILK 139 >2BL0-B nrPDB Length = 145 Score = 54.3 bits (129), Expect = 5e-08, Method: Composition-based stats. Identities = 21/158 (13%), Positives = 48/158 (30%), Gaps = 29/158 (18%) Query: 89 TKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHF 148 + ++Q ++ F + G V + G ++ Sbjct: 3 SADQIQECFQIFDKD-NDGKVSIEELGSALRSLGKNPTNAELNTI---------KGQLNA 52 Query: 149 EDF----VVGLSILLRGTVHEKLKW---AFNLYDINKDGCITKEEMLAIMKSIYDMMGRH 201 ++F + T E+ K AF D +G I + E+ ++ Sbjct: 53 KEFDLATFKTVYRKPIKTPTEQSKEMLDAFRALDKEGNGTIQEAELRQLL---------- 102 Query: 202 TYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETC 239 L + VE +++ + DG + + F++ Sbjct: 103 --LNLGDALTSSEVEELMKEVSVSGDGAINYESFVDML 138 Score = 34.3 bits (77), Expect = 0.050, Method: Composition-based stats. Identities = 21/91 (23%), Positives = 38/91 (41%), Gaps = 5/91 (5%) Query: 110 DEDTFKLIYSQFFPQGDATTYAHFLFNAF---DADGNGAIHFEDFVVGLSILLRGTVHEK 166 D TFK +Y + P T + + +AF D +GNG I + L L + Sbjct: 56 DLATFKTVYRK--PIKTPTEQSKEMLDAFRALDKEGNGTIQEAELRQLLLNLGDALTSSE 113 Query: 167 LKWAFNLYDINKDGCITKEEMLAIMKSIYDM 197 ++ ++ DG I E + ++ + Y + Sbjct: 114 VEELMKEVSVSGDGAINYESFVDMLVTGYPL 144 >5ZGM-A nrPDB Length = 110 Score = 53.9 bits (128), Expect = 6e-08, Method: Composition-based stats. Identities = 19/96 (19%), Positives = 38/96 (39%), Gaps = 11/96 (11%) Query: 144 GAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTY 203 G ++ F + L+G ++K F + D ++ G I +EE+ +++K + Sbjct: 23 GTFDYKRFFQLVG--LKGKSEAQVKEVFEILDKDQSGFIEEEELKSVLKG---------F 71 Query: 204 PILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETC 239 D + D + DG + DEF + Sbjct: 72 SAHGRDLSDTETKALLAAGDSDHDGKIGADEFAKMV 107 Score = 36.2 bits (82), Expect = 0.013, Method: Composition-based stats. Identities = 17/82 (20%), Positives = 30/82 (36%), Gaps = 3/82 (3%) Query: 113 TFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDF---VVGLSILLRGTVHEKLKW 169 +K + +G + +F D D +G I E+ + G S R + K Sbjct: 26 DYKRFFQLVGLKGKSEAQVKEVFEILDKDQSGFIEEEELKSVLKGFSAHGRDLSDTETKA 85 Query: 170 AFNLYDINKDGCITKEEMLAIM 191 D + DG I +E ++ Sbjct: 86 LLAAGDSDHDGKIGADEFAKMV 107 Score = 33.9 bits (76), Expect = 0.068, Method: Composition-based stats. Identities = 15/78 (19%), Positives = 35/78 (44%), Gaps = 3/78 (3%) Query: 81 QLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGD--ATTYAHFLFNAF 138 QL ++ +++ ++ + +G ++E+ K + F G + T L A Sbjct: 32 QLVGLKGKSEAQVKEVFEILDKD-QSGFIEEEELKSVLKGFSAHGRDLSDTETKALLAAG 90 Query: 139 DADGNGAIHFEDFVVGLS 156 D+D +G I ++F ++ Sbjct: 91 DSDHDGKIGADEFAKMVA 108 >1OQP-A nrPDB Length = 77 Score = 53.9 bits (128), Expect = 6e-08, Method: Composition-based stats. Identities = 23/82 (28%), Positives = 37/82 (45%), Gaps = 13/82 (15%) Query: 160 RGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFF 219 R + E LK AF L+D + G IT +++ + K L E+ E ++ Sbjct: 5 RDSREEILK-AFRLFDDDNSGTITIKDLRRVAKE------------LGENLTEEELQEMI 51 Query: 220 QKMDRNQDGVVTIDEFLETCQK 241 + DRN D + DEF+ +K Sbjct: 52 AEADRNDDNEIDEDEFIRIMKK 73 Score = 32.0 bits (71), Expect = 0.29, Method: Composition-based stats. Identities = 7/71 (9%), Positives = 26/71 (36%), Gaps = 2/71 (2%) Query: 89 TKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHF 148 +++E+ +R F ++ +G + + + + + D + + I Sbjct: 7 SREEILKAFRLFDDD-NSGTITIKDLRRVAKELGENLTEEEL-QEMIAEADRNDDNEIDE 64 Query: 149 EDFVVGLSILL 159 ++F+ + Sbjct: 65 DEFIRIMKKTS 75 Score = 30.4 bits (67), Expect = 0.75, Method: Composition-based stats. Identities = 18/60 (30%), Positives = 25/60 (41%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSI 194 F FD D +G I +D L E+L+ D N D I ++E + IMK Sbjct: 15 FRLFDDDNSGTITIKDLRRVAKELGENLTEEELQEMIAEADRNDDNEIDEDEFIRIMKKT 74 >1YX7-A nrPDB Length = 83 Score = 53.9 bits (128), Expect = 6e-08, Method: Composition-based stats. Identities = 22/78 (28%), Positives = 35/78 (44%), Gaps = 6/78 (7%) Query: 159 LRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERF 218 + V +L+ AF D N DG +T E+ M+ Y L +D E + Sbjct: 1 MACKVKAELEAAFKKLDANGDGYVTALELQTF------MVTLDAYKALSKDKVKEASAKL 54 Query: 219 FQKMDRNQDGVVTIDEFL 236 + D+N DG ++ +EFL Sbjct: 55 IKMADKNSDGKISKEEFL 72 Score = 37.0 bits (84), Expect = 0.008, Method: Composition-based stats. Identities = 20/64 (31%), Positives = 28/64 (43%), Gaps = 6/64 (9%) Query: 132 HFLFNAFDADGNGAI---HFEDFVVGL---SILLRGTVHEKLKWAFNLYDINKDGCITKE 185 F DA+G+G + + F+V L L + V E + D N DG I+KE Sbjct: 10 EAAFKKLDANGDGYVTALELQTFMVTLDAYKALSKDKVKEASAKLIKMADKNSDGKISKE 69 Query: 186 EMLA 189 E L Sbjct: 70 EFLN 73 >1Y1X-A nrPDB Length = 191 Score = 53.5 bits (127), Expect = 8e-08, Method: Composition-based stats. Identities = 32/166 (19%), Positives = 61/166 (36%), Gaps = 22/166 (13%) Query: 89 TKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFF-PQGDATTYAHFLFNAFDADGNGAIH 147 +EL +R + +G + S P ATT L + +D + +G I Sbjct: 25 DNQELMEWFRAVDTD-GSGAISVPELNAALSSAGVPFSLATT--EKLLHMYDKNHSGEIT 81 Query: 148 FEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILR 207 F++F +L ++ F D + DG + E+ A + S + T+ L Sbjct: 82 FDEFKDLHHFILS------MREGFRKRDSSGDGRLDSNEVRAALLSSGYQVSEQTFQAL- 134 Query: 208 EDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQLFE 253 +K DR + G + D+++E + N ++ Sbjct: 135 -----------MRKFDRQRRGSLGFDDYVELSIFVCRVRNVFAFYD 169 Score = 30.8 bits (68), Expect = 0.57, Method: Composition-based stats. Identities = 18/126 (14%), Positives = 41/126 (32%), Gaps = 9/126 (7%) Query: 66 ELELSTVRHQPEGLDQLQ-AQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQ 124 + + S PE L A F+ + L + +G + D FK ++ Sbjct: 37 DTDGSGAISVPELNAALSSAGVPFSLATTEKLLHMYDKN-HSGEITFDEFKDLHHFILSM 95 Query: 125 GDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITK 184 + F D+ G+G + + L + + +D + G + Sbjct: 96 REG-------FRKRDSSGDGRLDSNEVRAALLSSGYQVSEQTFQALMRKFDRQRRGSLGF 148 Query: 185 EEMLAI 190 ++ + + Sbjct: 149 DDYVEL 154 >5PAL-A nrPDB Length = 109 Score = 53.2 bits (126), Expect = 1e-07, Method: Composition-based stats. Identities = 22/110 (20%), Positives = 42/110 (38%), Gaps = 12/110 (10%) Query: 131 AHFLFNAFDADGN-GAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLA 189 A + A A + G ++ F + L+G ++K F + D ++ G I +EE+ Sbjct: 8 ADDINKAISAFKDPGTFDYKRFFHLVG--LKGKTDAQVKEVFEILDKDQSGFIEEEELKG 65 Query: 190 IMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETC 239 ++K + D + D + DG + DEF + Sbjct: 66 VLKG---------FSAHGRDLNDTETKALLAAGDSDHDGKIGADEFAKMV 106 Score = 36.2 bits (82), Expect = 0.012, Method: Composition-based stats. Identities = 17/82 (20%), Positives = 29/82 (35%), Gaps = 3/82 (3%) Query: 113 TFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDF---VVGLSILLRGTVHEKLKW 169 +K + +G +F D D +G I E+ + G S R + K Sbjct: 25 DYKRFFHLVGLKGKTDAQVKEVFEILDKDQSGFIEEEELKGVLKGFSAHGRDLNDTETKA 84 Query: 170 AFNLYDINKDGCITKEEMLAIM 191 D + DG I +E ++ Sbjct: 85 LLAAGDSDHDGKIGADEFAKMV 106 Score = 31.6 bits (70), Expect = 0.30, Method: Composition-based stats. Identities = 15/77 (19%), Positives = 32/77 (41%), Gaps = 3/77 (3%) Query: 82 LQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDA--TTYAHFLFNAFD 139 L T +++ ++ + +G ++E+ K + F G T L A D Sbjct: 32 LVGLKGKTDAQVKEVFEILDKD-QSGFIEEEELKGVLKGFSAHGRDLNDTETKALLAAGD 90 Query: 140 ADGNGAIHFEDFVVGLS 156 +D +G I ++F ++ Sbjct: 91 SDHDGKIGADEFAKMVA 107 >1TRF-A nrPDB Length = 76 Score = 53.2 bits (126), Expect = 1e-07, Method: Composition-based stats. Identities = 16/85 (18%), Positives = 38/85 (44%), Gaps = 12/85 (14%) Query: 157 ILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVE 216 L + + K AF+++D + G I+ +E+ +M+ L ++ E ++ Sbjct: 1 AFLSEEMIAEFKAAFDMFDADGGGDISTKELGTVMRM------------LGQNPTKEELD 48 Query: 217 RFFQKMDRNQDGVVTIDEFLETCQK 241 +++D + G + +EFL + Sbjct: 49 AIIEEVDEDGSGTIDFEEFLVMMVR 73 Score = 41.6 bits (96), Expect = 3e-04, Method: Composition-based stats. Identities = 11/76 (14%), Positives = 25/76 (32%), Gaps = 3/76 (3%) Query: 87 KFTKKELQSLYRGFK--NECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNG 144 +++ + F + G + + + D DG+G Sbjct: 2 FLSEEMIAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEEL-DAIIEEVDEDGSG 60 Query: 145 AIHFEDFVVGLSILLR 160 I FE+F+V + ++ Sbjct: 61 TIDFEEFLVMMVRQMK 76 Score = 38.5 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 18/57 (31%), Positives = 27/57 (47%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIM 191 F+ FDADG G I ++ + +L + E+L D + G I EE L +M Sbjct: 15 FDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGTIDFEEFLVMM 71 >5JOJ-A nrPDB Length = 97 Score = 53.2 bits (126), Expect = 1e-07, Method: Composition-based stats. Identities = 19/87 (21%), Positives = 36/87 (41%), Gaps = 10/87 (11%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRN 225 +L+ AF D + +G I+ E+ + K+ L E E D + Sbjct: 13 ELREAFAKVDTDGNGYISFNELNDLFKAAC--------LPLPGYRVREITENLMATGDLD 64 Query: 226 QDGVVTIDEFLETCQ--KDENIMNSMQ 250 QDG ++ DEF++ K ++ + + Sbjct: 65 QDGRISFDEFIKIFHGLKSTDVAKTFR 91 Score = 36.2 bits (82), Expect = 0.014, Method: Composition-based stats. Identities = 18/66 (27%), Positives = 27/66 (40%), Gaps = 4/66 (6%) Query: 135 FNAFDADGNGAIHFED----FVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAI 190 F D DGNG I F + F L V E + D+++DG I+ +E + I Sbjct: 18 FAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDLDQDGRISFDEFIKI 77 Query: 191 MKSIYD 196 + Sbjct: 78 FHGLKS 83 Score = 31.2 bits (69), Expect = 0.46, Method: Composition-based stats. Identities = 12/70 (17%), Positives = 23/70 (32%), Gaps = 5/70 (7%) Query: 89 TKKELQSLYRGFKN--ECPTGLVDEDTFKLIYS---QFFPQGDATTYAHFLFNAFDADGN 143 + +E+ L F G + + ++ P L D D + Sbjct: 7 SDEEMMELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDLDQD 66 Query: 144 GAIHFEDFVV 153 G I F++F+ Sbjct: 67 GRISFDEFIK 76 Score = 27.7 bits (60), Expect = 4.6, Method: Composition-based stats. Identities = 6/27 (22%), Positives = 14/27 (51%) Query: 208 EDAPLEHVERFFQKMDRNQDGVVTIDE 234 D + + F K+D + +G ++ +E Sbjct: 7 SDEEMMELREAFAKVDTDGNGYISFNE 33 >1SNL-A nrPDB Length = 103 Score = 53.2 bits (126), Expect = 1e-07, Method: Composition-based stats. Identities = 26/80 (32%), Positives = 43/80 (53%), Gaps = 4/80 (5%) Query: 168 KWAFNLYDINKDGCITKEEMLAI----MKSIYDMMGRHTYPILREDAPLEHVERFFQKMD 223 K F L+DIN DG + ++E+ A+ ++ +YD E+ L E + +D Sbjct: 23 KTFFILHDINSDGVLDEQELEALFTKELEKVYDPKNEEDDMREMEEERLRMREHVMKNVD 82 Query: 224 RNQDGVVTIDEFLETCQKDE 243 NQD +VT++EFL + Q+ E Sbjct: 83 TNQDRLVTLEEFLASTQRKE 102 >1JUO-A nrPDB Length = 198 Score = 52.8 bits (125), Expect = 1e-07, Method: Composition-based stats. Identities = 23/149 (15%), Positives = 55/149 (36%), Gaps = 24/149 (16%) Query: 106 TGLVDEDTFKLIYSQFFPQGDATTYA----HFLFNAFDADGNGAIHFEDFVVGLSILLRG 161 G +D D + +Q G + + + D D +G + F +F ++L Sbjct: 46 DGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVL--- 102 Query: 162 TVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQK 221 + F +D ++ G + +E+ + ++ + + V ++ Sbjct: 103 ---NGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSP------------QAVNSIAKR 147 Query: 222 MDRNQDGVVTIDEFLETCQKDENIMNSMQ 250 N G +T D+++ C K + +S + Sbjct: 148 YSTN--GKITFDDYIACCVKLRALTDSFR 174 Score = 28.5 bits (62), Expect = 3.0, Method: Composition-based stats. Identities = 13/61 (21%), Positives = 22/61 (36%), Gaps = 7/61 (11%) Query: 178 KDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLE 237 +DG I +E+ + G + LE +DR+ G + +EF E Sbjct: 45 QDGQIDADELQRCLTQSGIAGGYKPFN-------LETCRLMVSMLDRDMSGTMGFNEFKE 97 Query: 238 T 238 Sbjct: 98 L 98 >5JOL-A nrPDB Length = 82 Score = 52.8 bits (125), Expect = 2e-07, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 31/73 (42%), Gaps = 8/73 (10%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRN 225 +L+ AF D + +G I+ E+ + K+ L E E D + Sbjct: 13 ELREAFAKVDTDGNGYISFNELNDLFKAAC--------LPLPGYRVREITENLMATGDLD 64 Query: 226 QDGVVTIDEFLET 238 QDG ++ DEF++ Sbjct: 65 QDGRISFDEFIKI 77 Score = 36.2 bits (82), Expect = 0.015, Method: Composition-based stats. Identities = 18/64 (28%), Positives = 27/64 (42%), Gaps = 4/64 (6%) Query: 135 FNAFDADGNGAIHFED----FVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAI 190 F D DGNG I F + F L V E + D+++DG I+ +E + I Sbjct: 18 FAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDLDQDGRISFDEFIKI 77 Query: 191 MKSI 194 + Sbjct: 78 FHGL 81 Score = 31.2 bits (69), Expect = 0.45, Method: Composition-based stats. Identities = 12/70 (17%), Positives = 23/70 (32%), Gaps = 5/70 (7%) Query: 89 TKKELQSLYRGFKN--ECPTGLVDEDTFKLIYS---QFFPQGDATTYAHFLFNAFDADGN 143 + +E+ L F G + + ++ P L D D + Sbjct: 7 SDEEMMELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDLDQD 66 Query: 144 GAIHFEDFVV 153 G I F++F+ Sbjct: 67 GRISFDEFIK 76 Score = 27.7 bits (60), Expect = 4.5, Method: Composition-based stats. Identities = 6/27 (22%), Positives = 14/27 (51%) Query: 208 EDAPLEHVERFFQKMDRNQDGVVTIDE 234 D + + F K+D + +G ++ +E Sbjct: 7 SDEEMMELREAFAKVDTDGNGYISFNE 33 >1H4B-A nrPDB Length = 84 Score = 52.8 bits (125), Expect = 2e-07, Method: Composition-based stats. Identities = 14/77 (18%), Positives = 33/77 (42%), Gaps = 13/77 (16%) Query: 171 FNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVV 230 F +D N DG I+ E+ +K++ + + V+ ++D + DG + Sbjct: 15 FKRFDANGDGKISAAELGEALKTLGSITP-------------DEVKHMMAEIDTDGDGFI 61 Query: 231 TIDEFLETCQKDENIMN 247 + EF + + + ++ Sbjct: 62 SFQEFTDFGRANRGLLK 78 Score = 39.7 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 17/70 (24%), Positives = 27/70 (38%), Gaps = 1/70 (1%) Query: 124 QGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCIT 183 +F FDA+G+G I + L L T E +K D + DG I+ Sbjct: 4 HPQDKAERERIFKRFDANGDGKISAAELGEALKTLGSITPDE-VKHMMAEIDTDGDGFIS 62 Query: 184 KEEMLAIMKS 193 +E ++ Sbjct: 63 FQEFTDFGRA 72 Score = 37.4 bits (85), Expect = 0.007, Method: Composition-based stats. Identities = 11/63 (17%), Positives = 20/63 (31%), Gaps = 3/63 (4%) Query: 89 TKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHF 148 K E + +++ F G + + D DG+G I F Sbjct: 7 DKAERERIFKRFDAN-GDGKISAAELGEALKTLGSITPDE--VKHMMAEIDTDGDGFISF 63 Query: 149 EDF 151 ++F Sbjct: 64 QEF 66 Score = 27.3 bits (59), Expect = 6.3, Method: Composition-based stats. Identities = 9/27 (33%), Positives = 14/27 (51%) Query: 214 HVERFFQKMDRNQDGVVTIDEFLETCQ 240 ER F++ D N DG ++ E E + Sbjct: 10 ERERIFKRFDANGDGKISAAELGEALK 36 >1TNP-A nrPDB Length = 90 Score = 52.4 bits (124), Expect = 2e-07, Method: Composition-based stats. Identities = 16/85 (18%), Positives = 38/85 (44%), Gaps = 12/85 (14%) Query: 157 ILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVE 216 L + + K AF+++D + G I+ +E+ +M+ L ++ E ++ Sbjct: 12 AFLSEEMIAEFKAAFDMFDADGGGDISTKELGTVMRM------------LGQNPTKEELD 59 Query: 217 RFFQKMDRNQDGVVTIDEFLETCQK 241 +++D + G + +EFL + Sbjct: 60 AIIEEVDEDGSGTIDFEEFLVMMVR 84 Score = 44.3 bits (103), Expect = 6e-05, Method: Composition-based stats. Identities = 13/84 (15%), Positives = 29/84 (34%), Gaps = 3/84 (3%) Query: 80 DQLQAQTKFTKKELQSLYRGFK--NECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNA 137 Q +A+ +++ + F + G + + + Sbjct: 6 QQAEARAFLSEEMIAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEEL-DAIIEE 64 Query: 138 FDADGNGAIHFEDFVVGLSILLRG 161 D DG+G I FE+F+V + ++ Sbjct: 65 VDEDGSGTIDFEEFLVMMVRQMKE 88 Score = 38.1 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 18/57 (31%), Positives = 27/57 (47%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIM 191 F+ FDADG G I ++ + +L + E+L D + G I EE L +M Sbjct: 26 FDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGTIDFEEFLVMM 82 >2OPO-A nrPDB Length = 86 Score = 52.4 bits (124), Expect = 2e-07, Method: Composition-based stats. Identities = 16/80 (20%), Positives = 35/80 (43%), Gaps = 13/80 (16%) Query: 171 FNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVV 230 F +D N DG I+ E+ +K++ + + V R ++D + DG + Sbjct: 17 FKRFDTNGDGKISSSELGDALKTLGSVTP-------------DEVRRMMAEIDTDGDGFI 63 Query: 231 TIDEFLETCQKDENIMNSMQ 250 + DEF + + + ++ + Sbjct: 64 SFDEFTDFARANRGLVKDVS 83 Score = 40.4 bits (93), Expect = 7e-04, Method: Composition-based stats. Identities = 15/68 (22%), Positives = 28/68 (41%), Gaps = 1/68 (1%) Query: 132 HFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIM 191 +F FD +G+G I + L L T E ++ D + DG I+ +E Sbjct: 14 ERIFKRFDTNGDGKISSSELGDALKTLGSVTPDE-VRRMMAEIDTDGDGFISFDEFTDFA 72 Query: 192 KSIYDMMG 199 ++ ++ Sbjct: 73 RANRGLVK 80 Score = 36.2 bits (82), Expect = 0.014, Method: Composition-based stats. Identities = 9/58 (15%), Positives = 18/58 (31%), Gaps = 3/58 (5%) Query: 94 QSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDF 151 + +++ F G + + D DG+G I F++F Sbjct: 14 ERIFKRFDTN-GDGKISSSELGDALKTLGSVTPDE--VRRMMAEIDTDGDGFISFDEF 68 Score = 28.5 bits (62), Expect = 2.9, Method: Composition-based stats. Identities = 11/29 (37%), Positives = 16/29 (55%), Gaps = 2/29 (6%) Query: 208 EDAPLE--HVERFFQKMDRNQDGVVTIDE 234 ED P + ER F++ D N DG ++ E Sbjct: 4 EDTPQDIADRERIFKRFDTNGDGKISSSE 32 >2Q4U-A nrPDB Length = 272 Score = 52.4 bits (124), Expect = 2e-07, Method: Composition-based stats. Identities = 26/176 (14%), Positives = 65/176 (36%), Gaps = 23/176 (13%) Query: 95 SLYRGFKNECPT---GLVDEDTFKLIYSQFFPQGDAT-----TYAHFLFNAFDADGNGAI 146 +++ F + G +D F+ + + P+ T +A+DA +G + Sbjct: 15 QIWQHFDADDNGYIEGKELDDFFRHMLKKLQPKDKITDERVQQIKKSFMSAYDATFDGRL 74 Query: 147 HFEDFVVG---------LSILLRGTVHEKLKWA--FNLYDINKDGCITKEEMLAIMKSIY 195 E+ L + +++ + YD + G I+ E+ +K ++ Sbjct: 75 QIEELANMILPQEENFLLIFRREAPLDNSVEFMKIWRKYDADSSGYISAAELKNFLKDLF 134 Query: 196 DMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQL 251 + P + E+ + + D+N+DG + +++ EN + ++ Sbjct: 135 LQHKKKIPP----NKLDEYTDAMMKIFDKNKDGRLDLNDLARILALQENFLLQFKM 186 Score = 44.7 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 28/178 (15%), Positives = 62/178 (34%), Gaps = 21/178 (11%) Query: 78 GLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHF---- 133 L +LQ + K T + +Q + + F + + + + PQ + Sbjct: 40 MLKKLQPKDKITDERVQQIKKSFMSAYDATFDGRLQIEELANMILPQEENFLLIFRREAP 99 Query: 134 ---------LFNAFDADGNGAIHFED---FVVGLSILLRGT-----VHEKLKWAFNLYDI 176 ++ +DAD +G I + F+ L + + + E ++D Sbjct: 100 LDNSVEFMKIWRKYDADSSGYISAAELKNFLKDLFLQHKKKIPPNKLDEYTDAMMKIFDK 159 Query: 177 NKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDE 234 NKDG + ++ I+ + + + + E+ F D ++ G + E Sbjct: 160 NKDGRLDLNDLARILALQENFLLQFKMDASSQVERKRDFEKIFAHYDVSRTGALEGPE 217 Score = 44.3 bits (103), Expect = 5e-05, Method: Composition-based stats. Identities = 26/162 (16%), Positives = 55/162 (33%), Gaps = 24/162 (14%) Query: 92 ELQSLYRGFKNECPTGLVDEDTFKLIYSQFF-------PQGDATTYAHFLFNAFDADGNG 144 E ++R + + +G + K F P Y + FD + +G Sbjct: 105 EFMKIWRKYDAD-SSGYISAAELKNFLKDLFLQHKKKIPPNKLDEYTDAMMKIFDKNKDG 163 Query: 145 AIHFEDFVVGLSILLRGTVHEKL------------KWAFNLYDINKDGCITKEEMLAIMK 192 + D L++ + K+ + F YD+++ G + E+ +K Sbjct: 164 RLDLNDLARILALQENFLLQFKMDASSQVERKRDFEKIFAHYDVSRTGALEGPEVDGFVK 223 Query: 193 SIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDE 234 + +++ P + + E D N+DG + E Sbjct: 224 DMMELV----RPSISGGDLDKFRECLLTHCDMNKDGKIQKSE 261 Score = 27.7 bits (60), Expect = 5.7, Method: Composition-based stats. Identities = 23/117 (19%), Positives = 43/117 (36%), Gaps = 19/117 (16%) Query: 91 KELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQG-----DATTYAHF------LFNAFD 139 E ++ G +D + I + DA++ +F +D Sbjct: 147 DEYTDAMMKIFDKNKDGRLDLNDLARILALQENFLLQFKMDASSQVERKRDFEKIFAHYD 206 Query: 140 ADGNGAIHFED---FVVGLSILLRGTVH----EKLKWAFNLY-DINKDGCITKEEML 188 GA+ + FV + L+R ++ +K + + D+NKDG I K E+ Sbjct: 207 VSRTGALEGPEVDGFVKDMMELVRPSISGGDLDKFRECLLTHCDMNKDGKIQKSELA 263 >5MRA-A nrPDB Length = 167 Score = 52.0 bits (123), Expect = 2e-07, Method: Composition-based stats. Identities = 23/149 (15%), Positives = 55/149 (36%), Gaps = 24/149 (16%) Query: 106 TGLVDEDTFKLIYSQFFPQGDATTYA----HFLFNAFDADGNGAIHFEDFVVGLSILLRG 161 G +D D + +Q G + + + D D +G + F +F ++L Sbjct: 15 DGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVL--- 71 Query: 162 TVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQK 221 + F +D ++ G + +E+ + ++ + + V ++ Sbjct: 72 ---NGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSP------------QAVNSIAKR 116 Query: 222 MDRNQDGVVTIDEFLETCQKDENIMNSMQ 250 N G +T D+++ C K + +S + Sbjct: 117 YSTN--GKITFDDYIACCVKLRALTDSFR 143 Score = 28.1 bits (61), Expect = 3.6, Method: Composition-based stats. Identities = 13/61 (21%), Positives = 22/61 (36%), Gaps = 7/61 (11%) Query: 178 KDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLE 237 +DG I +E+ + G + LE +DR+ G + +EF E Sbjct: 14 QDGQIDADELQRCLTQSGIAGGYKPFN-------LETCRLMVSMLDRDMSGTMGFNEFKE 66 Query: 238 T 238 Sbjct: 67 L 67 >2I18-A nrPDB Length = 64 Score = 52.0 bits (123), Expect = 2e-07, Method: Composition-based stats. Identities = 23/73 (31%), Positives = 33/73 (45%), Gaps = 16/73 (21%) Query: 167 LKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQ 226 LK + L D++ DG +TKEE+ + K +E V K D N Sbjct: 7 LKVLYKLMDVDGDGKLTKEEVTSFFKKHG----------------IEKVAEQVMKADANG 50 Query: 227 DGVVTIDEFLETC 239 DG +T++EFLE Sbjct: 51 DGYITLEEFLEFS 63 Score = 30.8 bits (68), Expect = 0.58, Method: Composition-based stats. Identities = 17/57 (29%), Positives = 25/57 (43%), Gaps = 4/57 (7%) Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAI 190 L+ D DG+G + E+ ++ + EK+ D N DG IT EE L Sbjct: 10 LYKLMDVDGDGKLTKEE----VTSFFKKHGIEKVAEQVMKADANGDGYITLEEFLEF 62 >3I5H-B nrPDB Length = 153 Score = 51.6 bits (122), Expect = 3e-07, Method: Composition-based stats. Identities = 24/137 (17%), Positives = 61/137 (44%), Gaps = 8/137 (5%) Query: 80 DQLQAQTKFTKKELQSLYRGFK--NECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNA 137 ++ + K +++++Q L F ++ G + + K ++S L Sbjct: 2 EEAPRRVKLSQRQMQELKEAFTMIDQDRDGFIGMEDLKDMFSSLGRVPPDDELNAML--- 58 Query: 138 FDADGNGAIHFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYD 196 + G ++F F+ + GT + L+ AF+++D + G I ++ + +++++ D Sbjct: 59 --KECPGQLNFTAFLTLFGEKVSGTDPEDALRNAFSMFDEDGQGFIPEDYLKDLLENMGD 116 Query: 197 MMGRHTYPILREDAPLE 213 + + +DAPL+ Sbjct: 117 NFSKEEIKNVWKDAPLK 133 >2M8U-A nrPDB Length = 77 Score = 51.6 bits (122), Expect = 3e-07, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 31/74 (41%), Gaps = 12/74 (16%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRN 225 ++ AF ++D + +G +T + + ++ + DMM P + +E + D Sbjct: 12 QVIEAFKVFDRDGNGYVTVDYLRKVLNELGDMM------------PADEIEEMIYEADPQ 59 Query: 226 QDGVVTIDEFLETC 239 G V + F+ Sbjct: 60 NSGYVQYETFVGML 73 >6IIE-A nrPDB Length = 93 Score = 51.6 bits (122), Expect = 3e-07, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 35/77 (45%), Gaps = 3/77 (3%) Query: 161 GTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQ 220 G +KL++ F LYD +++G + E+ I I MM Y ++ + Sbjct: 5 GRPEDKLEFTFKLYDTDRNGILDSSEVDKI---ILQMMRVAEYLDWDVSELRPILQEMMK 61 Query: 221 KMDRNQDGVVTIDEFLE 237 ++D + G V+ E++ Sbjct: 62 EIDYDGSGSVSQAEWVR 78 Score = 28.5 bits (62), Expect = 3.3, Method: Composition-based stats. Identities = 5/31 (16%), Positives = 13/31 (41%) Query: 129 TYAHFLFNAFDADGNGAIHFEDFVVGLSILL 159 + D DG+G++ ++V + + Sbjct: 54 PILQEMMKEIDYDGSGSVSQAEWVRAGATTV 84 Score = 27.0 bits (58), Expect = 8.1, Method: Composition-based stats. Identities = 12/71 (16%), Positives = 24/71 (33%), Gaps = 9/71 (12%) Query: 125 GDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLR---------GTVHEKLKWAFNLYD 175 G F F +D D NG + + + ++R + L+ D Sbjct: 5 GRPEDKLEFTFKLYDTDRNGILDSSEVDKIILQMMRVAEYLDWDVSELRPILQEMMKEID 64 Query: 176 INKDGCITKEE 186 + G +++ E Sbjct: 65 YDGSGSVSQAE 75 >5XND-A nrPDB Length = 114 Score = 51.2 bits (121), Expect = 4e-07, Method: Composition-based stats. Identities = 21/97 (21%), Positives = 39/97 (40%), Gaps = 11/97 (11%) Query: 144 GAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTY 203 G+ + F L G +++K AF + D +K G I +EE+ +++ + Sbjct: 28 GSFDHKKFFKACG--LSGKSTDEVKKAFAIIDQDKSGFIEEEELKLFLQN---------F 76 Query: 204 PILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQ 240 + F + D + DG + IDEF + Sbjct: 77 KAGARALSDAETKAFLKAGDSDGDGKIGIDEFAAMIK 113 Score = 38.1 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 19/82 (23%), Positives = 29/82 (35%), Gaps = 3/82 (3%) Query: 115 KLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFED---FVVGLSILLRGTVHEKLKWAF 171 K + G +T F D D +G I E+ F+ R + K Sbjct: 33 KKFFKACGLSGKSTDEVKKAFAIIDQDKSGFIEEEELKLFLQNFKAGARALSDAETKAFL 92 Query: 172 NLYDINKDGCITKEEMLAIMKS 193 D + DG I +E A++K Sbjct: 93 KAGDSDGDGKIGIDEFAAMIKG 114 Score = 33.1 bits (74), Expect = 0.11, Method: Composition-based stats. Identities = 16/73 (21%), Positives = 31/73 (42%), Gaps = 4/73 (5%) Query: 87 KFTKKELQSLYRGF--KNECPTGLVDEDTFKLIYSQFFPQGDATTYAH--FLFNAFDADG 142 + K + + F ++ +G ++E+ KL F A + A A D+DG Sbjct: 40 GLSGKSTDEVKKAFAIIDQDKSGFIEEEELKLFLQNFKAGARALSDAETKAFLKAGDSDG 99 Query: 143 NGAIHFEDFVVGL 155 +G I ++F + Sbjct: 100 DGKIGIDEFAAMI 112 >6MI5-X nrPDB Length = 117 Score = 51.2 bits (121), Expect = 4e-07, Method: Composition-based stats. Identities = 22/101 (21%), Positives = 40/101 (39%), Gaps = 13/101 (12%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEML-AIMKS 193 AFD D +G I ++ + S AF+ D +KDG + +E+ + ++ Sbjct: 9 IAAFDPDKDGTIDLKEALAAGSA------------AFDKLDPDKDGTLDAKELKGRVSEA 56 Query: 194 IYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDE 234 + L + L VE F+ + + DG + E Sbjct: 57 DLKKLDPDNDGTLDKKEYLAAVEAQFKAANPDNDGTIDARE 97 Score = 30.8 bits (68), Expect = 0.52, Method: Composition-based stats. Identities = 13/93 (13%), Positives = 26/93 (27%), Gaps = 26/93 (27%) Query: 99 GFKNECPT--GLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLS 156 F P G +D K + D D +G + ++++ + Sbjct: 32 AFDKLDPDKDGTLDAKELK------------GRVSEADLKKLDPDNDGTLDKKEYLAAVE 79 Query: 157 ILLRGTVHEKLKWAFNLYDINKDGCITKEEMLA 189 F + + DG I E+ + Sbjct: 80 AQ------------FKAANPDNDGTIDARELAS 100 >4P5W-A nrPDB Length = 411 Score = 51.2 bits (121), Expect = 5e-07, Method: Composition-based stats. Identities = 23/118 (19%), Positives = 44/118 (37%), Gaps = 5/118 (4%) Query: 77 EGLDQLQAQTKFTKKELQSLYRGFKNECPTG--LVDEDTFKLIYSQFFPQGDATTY-AHF 133 E ++ + EL++++ + + G + + F Y F + Sbjct: 23 EAAAKVALTKRADPAELRTIFLKYASIEKNGEFFMSPNDFVTRYLNIFGESQPNPKTVEL 82 Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIM 191 L D +G I F++FV S+L AF L+D G +T E++ + Sbjct: 83 LSGVVDQTKDGLISFQEFVAFESVLCA--PDALFMVAFQLFDKAGKGEVTFEDVKQVF 138 Score = 34.7 bits (78), Expect = 0.041, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 31/77 (40%), Gaps = 4/77 (5%) Query: 181 CITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLE--- 237 + E+ S D + R+ + VE +D+ +DG+++ EF+ Sbjct: 46 YASIEKNGEFFMSPNDFVTRYLNIFGESQPNPKTVELLSGVVDQTKDGLISFQEFVAFES 105 Query: 238 -TCQKDENIMNSMQLFE 253 C D M + QLF+ Sbjct: 106 VLCAPDALFMVAFQLFD 122 >5VLN-A nrPDB Length = 120 Score = 50.8 bits (120), Expect = 5e-07, Method: Composition-based stats. Identities = 14/88 (15%), Positives = 32/88 (36%), Gaps = 1/88 (1%) Query: 82 LQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDAD 141 ++ T+ K E ++ + F G + + + + D D Sbjct: 9 VEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPTPEEL-QEMIDEVDED 67 Query: 142 GNGAIHFEDFVVGLSILLRGTVHEKLKW 169 G+G + F++F+V + ++ K K Sbjct: 68 GSGTVDFDEFLVMMVRSMKDDSKGKFKR 95 Score = 43.5 bits (101), Expect = 9e-05, Method: Composition-based stats. Identities = 18/91 (19%), Positives = 36/91 (39%), Gaps = 13/91 (14%) Query: 153 VGLSILLRGTVHEKLKWAFNLYDINK-DGCITKEEMLAIMKSIYDMMGRHTYPILREDAP 211 L + K AF+++ + DG I+ +E+ +M+ L ++ Sbjct: 6 KAAVEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRM------------LGQNPT 53 Query: 212 LEHVERFFQKMDRNQDGVVTIDEFLETCQKD 242 E ++ ++D + G V DEFL + Sbjct: 54 PEELQEMIDEVDEDGSGTVDFDEFLVMMVRS 84 Score = 28.1 bits (61), Expect = 4.2, Method: Composition-based stats. Identities = 11/78 (14%), Positives = 28/78 (35%) Query: 143 NGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHT 202 +G+I ++ + +L + E+L+ + D + G + +E L +M + Sbjct: 33 DGSISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRSMKDDSKGK 92 Query: 203 YPILREDAPLEHVERFFQ 220 + + Q Sbjct: 93 FKRPTLRRVRISADAMMQ 110 >2N7L-C nrPDB Length = 141 Score = 50.5 bits (119), Expect = 7e-07, Method: Composition-based stats. Identities = 12/84 (14%), Positives = 30/84 (35%), Gaps = 1/84 (1%) Query: 82 LQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDAD 141 ++ T+ K E ++ + F G + + + + D D Sbjct: 24 VEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPTPEEL-QEMIDEVDED 82 Query: 142 GNGAIHFEDFVVGLSILLRGTVHE 165 G+G + F++F+V + ++ Sbjct: 83 GSGTVDFDEFLVMMVRXMKDDSEN 106 Score = 43.9 bits (102), Expect = 6e-05, Method: Composition-based stats. Identities = 18/90 (20%), Positives = 36/90 (40%), Gaps = 13/90 (14%) Query: 153 VGLSILLRGTVHEKLKWAFNLYDINK-DGCITKEEMLAIMKSIYDMMGRHTYPILREDAP 211 L + K AF+++ + DG I+ +E+ +M+ L ++ Sbjct: 21 KAAVEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRM------------LGQNPT 68 Query: 212 LEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 E ++ ++D + G V DEFL + Sbjct: 69 PEELQEMIDEVDEDGSGTVDFDEFLVMMVR 98 Score = 28.5 bits (62), Expect = 3.3, Method: Composition-based stats. Identities = 11/61 (18%), Positives = 26/61 (42%) Query: 143 NGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHT 202 +G+I ++ + +L + E+L+ + D + G + +E L +M + Sbjct: 48 DGSISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRXMKDDSENL 107 Query: 203 Y 203 Y Sbjct: 108 Y 108 >4P5X-A nrPDB Length = 315 Score = 50.1 bits (118), Expect = 9e-07, Method: Composition-based stats. Identities = 28/185 (15%), Positives = 67/185 (36%), Gaps = 28/185 (15%) Query: 81 QLQAQTKFTKKELQSLYRGFKNECPTG--LVDEDTFKLIYSQFFPQGDATT-YAHFLFNA 137 ++Q + EL++++ + + G + + F Y + ++ L Sbjct: 8 KVQTTKRGDPHELRNIFLQYASTEVDGERYMTPEDFVQRYLGLYNDPNSNPKIVQLLAGV 67 Query: 138 FDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIM------ 191 D +G I +++F+ S+L AF L+D + +G +T E + I Sbjct: 68 ADQTKDGLISYQEFLAFESVLCA--PDSMFIVAFQLFDKSGNGEVTFENVKEIFGQTIIH 125 Query: 192 -----------------KSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDE 234 + + + ++ LEH + F D+++ G+++ + Sbjct: 126 HHIPFNWDCEFIRLHFGHNRKKHLNYTEFTQFLQELQLEHARQAFALKDKSKSGMISGLD 185 Query: 235 FLETC 239 F + Sbjct: 186 FSDIM 190 Score = 28.5 bits (62), Expect = 3.0, Method: Composition-based stats. Identities = 32/174 (18%), Positives = 53/174 (30%), Gaps = 36/174 (20%) Query: 96 LYRGFKNECPTGLVDEDTFKLIYSQ-----FFPQGDATTYAHFLFNAFDADGNGAIHFED 150 ++ F G V + K I+ Q P + F F Sbjct: 98 AFQLFDK-SGNGEVTFENVKEIFGQTIIHHHIPFNWDCEFIRLHFGHNRKKHLNYTEFTQ 156 Query: 151 FVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYD-MMGRHTYPILRED 209 F+ L + E + AF L D +K G I+ + IM +I M+ L Sbjct: 157 FLQELQL-------EHARQAFALKDKSKSGMISGLDFSDIMVTIRSHMLTPFVEENLVSA 209 Query: 210 AP---------------------LEHVERFFQ-KMDRNQDGVVTIDEFLETCQK 241 A +E V + + +D VT +EF ++ + Sbjct: 210 AGGSISHQVSFSYFNAFNSLLNNMELVRKIYSTLAGTRKDVEVTKEEFAQSAIR 263 >5TBY-E nrPDB Length = 166 Score = 50.1 bits (118), Expect = 1e-06, Method: Composition-based stats. Identities = 22/160 (13%), Positives = 50/160 (31%), Gaps = 19/160 (11%) Query: 88 FTKKELQSLYRGF--KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGA 145 F + ++Q F ++ G +D++ + ++ + G Sbjct: 21 FEQTQIQEFKEAFTIMDQNRDGFIDKNDLRDTFAALGRVNVKNEEIDEMIKE----APGP 76 Query: 146 IHFEDFVVGLSILLRG-TVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYP 204 I+F F+ L+G E + AF ++D G + + + ++ Sbjct: 77 INFTVFLTMFGEKLKGADPEETILNAFKVFDPEGKGVLKADYVREML------------T 124 Query: 205 ILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDEN 244 E E V++ F + G + + E Sbjct: 125 TQAERFSKEEVDQMFAAFPPDVTGNLDYKNLVHIITHGEE 164 Score = 41.2 bits (95), Expect = 5e-04, Method: Composition-based stats. Identities = 17/96 (17%), Positives = 40/96 (41%), Gaps = 22/96 (22%) Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDR 224 ++ K AF + D N+DG I K ++ ++ + ++ E ++ ++ Sbjct: 27 QEFKEAFTIMDQNRDGFIDKNDLRDTFAALGRVNVKN-----------EEIDEMIKEA-- 73 Query: 225 NQDGVVTIDEF-------LETCQKDENIMNSMQLFE 253 G + F L+ +E I+N+ ++F+ Sbjct: 74 --PGPINFTVFLTMFGEKLKGADPEETILNAFKVFD 107 >1F55-A nrPDB Length = 77 Score = 49.7 bits (117), Expect = 1e-06, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 30/76 (39%), Gaps = 12/76 (15%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRN 225 + K AF L+D + +G I+ E+ +M+S L V ++D + Sbjct: 11 EFKEAFALFDKDNNGSISSSELATVMRS------------LGLSPSEAEVNDLMNEIDVD 58 Query: 226 QDGVVTIDEFLETCQK 241 + + EFL + Sbjct: 59 GNHQIEFSEFLALMSR 74 Score = 43.9 bits (102), Expect = 7e-05, Method: Composition-based stats. Identities = 13/78 (16%), Positives = 27/78 (34%), Gaps = 3/78 (3%) Query: 85 QTKFTKKELQSLYRGF--KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADG 142 + T++++ F ++ G + + + N D DG Sbjct: 1 SSNLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLM-NEIDVDG 59 Query: 143 NGAIHFEDFVVGLSILLR 160 N I F +F+ +S L+ Sbjct: 60 NHQIEFSEFLALMSRQLK 77 Score = 33.1 bits (74), Expect = 0.12, Method: Composition-based stats. Identities = 15/57 (26%), Positives = 24/57 (42%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIM 191 F FD D NG+I + + L ++ N D++ + I E LA+M Sbjct: 16 FALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQIEFSEFLALM 72 >2K2I-A nrPDB Length = 79 Score = 49.3 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 23/82 (28%), Positives = 38/82 (46%), Gaps = 13/82 (15%) Query: 160 RGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFF 219 + T E LK AF L+D ++ G I+ + + + K L E+ E ++ Sbjct: 7 KDTKEEILK-AFKLFDDDETGKISFKNLKRVAKE------------LGENLTDEELQEMI 53 Query: 220 QKMDRNQDGVVTIDEFLETCQK 241 + DR+ DG V+ EFL +K Sbjct: 54 DEADRDGDGEVSEQEFLRIMKK 75 Score = 33.5 bits (75), Expect = 0.098, Method: Composition-based stats. Identities = 13/77 (16%), Positives = 31/77 (40%), Gaps = 2/77 (2%) Query: 83 QAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADG 142 + K TK+E+ ++ F ++ TG + K + + + + D DG Sbjct: 3 KMSEKDTKEEILKAFKLFDDD-ETGKISFKNLKRVAKELGENLTDEEL-QEMIDEADRDG 60 Query: 143 NGAIHFEDFVVGLSILL 159 +G + ++F+ + Sbjct: 61 DGEVSEQEFLRIMKKTS 77 Score = 33.1 bits (74), Expect = 0.11, Method: Composition-based stats. Identities = 18/60 (30%), Positives = 28/60 (46%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSI 194 F FD D G I F++ L E+L+ + D + DG ++++E L IMK Sbjct: 17 FKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKKT 76 >2KYF-A nrPDB Length = 108 Score = 49.3 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 15/83 (18%), Positives = 30/83 (36%), Gaps = 9/83 (10%) Query: 159 LRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERF 218 + +LK F + D ++ G I ++E+ ++ + + F Sbjct: 35 MSKKSSSQLKEIFRILDNDQSGFIEEDELKYFLQ---------RFESGARVLTASETKTF 85 Query: 219 FQKMDRNQDGVVTIDEFLETCQK 241 D + DG + +EF E Q Sbjct: 86 LAAADHDGDGKIGAEEFQEMVQS 108 Score = 33.9 bits (76), Expect = 0.072, Method: Composition-based stats. Identities = 16/82 (19%), Positives = 29/82 (35%), Gaps = 3/82 (3%) Query: 115 KLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGT---VHEKLKWAF 171 K + +++ +F D D +G I ++ L G + K Sbjct: 27 KKFFQISGMSKKSSSQLKEIFRILDNDQSGFIEEDELKYFLQRFESGARVLTASETKTFL 86 Query: 172 NLYDINKDGCITKEEMLAIMKS 193 D + DG I EE +++S Sbjct: 87 AAADHDGDGKIGAEEFQEMVQS 108 >1GJY-A nrPDB Length = 167 Score = 48.9 bits (115), Expect = 2e-06, Method: Composition-based stats. Identities = 22/149 (14%), Positives = 53/149 (35%), Gaps = 24/149 (16%) Query: 106 TGLVDEDTFKLIYSQFFPQGDATTYA----HFLFNAFDADGNGAIHFEDFVVGLSILLRG 161 G +D D + +Q G + + + D D +G + F +F ++L Sbjct: 15 DGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVL--- 71 Query: 162 TVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQK 221 + F +D ++ G + +E+ + ++ + T + + Sbjct: 72 ---NGWRQHFISFDSDRSGTVDPQELQKALTTMGFRLNPQTVNSIAKRYSTS-------- 120 Query: 222 MDRNQDGVVTIDEFLETCQKDENIMNSMQ 250 G +T D+++ C K + +S + Sbjct: 121 ------GKITFDDYIACCVKLRALTDSFR 143 Score = 27.7 bits (60), Expect = 4.4, Method: Composition-based stats. Identities = 13/61 (21%), Positives = 22/61 (36%), Gaps = 7/61 (11%) Query: 178 KDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLE 237 +DG I +E+ + G + LE +DR+ G + +EF E Sbjct: 14 QDGQIDADELQRCLTQSGIAGGYKPFN-------LETCRLMVSMLDRDMSGTMGFNEFKE 66 Query: 238 T 238 Sbjct: 67 L 67 >2NCO-A nrPDB Length = 102 Score = 48.5 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 20/75 (26%), Positives = 36/75 (48%), Gaps = 5/75 (6%) Query: 168 KWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQD 227 + F YD + G + +E+ ++K Y MG + +ED V+ + Q D N D Sbjct: 18 RRLFKRYDKDGSGQLQDDEIAGLLKDTYAEMGMSNFTPTKED-----VKIWLQMADTNSD 72 Query: 228 GVVTIDEFLETCQKD 242 G V+++E+ + K Sbjct: 73 GSVSLEEYEDLIIKS 87 Score = 31.6 bits (70), Expect = 0.36, Method: Composition-based stats. Identities = 18/93 (19%), Positives = 35/93 (37%), Gaps = 8/93 (8%) Query: 120 QFFPQGDATT-YAHFLFNAFDADGNGAIHFEDFVVG-------LSILLRGTVHEKLKWAF 171 ++ P+ +A A LF +D DG+G + ++ + + E +K Sbjct: 5 KYNPEVEAKLDVARRLFKRYDKDGSGQLQDDEIAGLLKDTYAEMGMSNFTPTKEDVKIWL 64 Query: 172 NLYDINKDGCITKEEMLAIMKSIYDMMGRHTYP 204 + D N DG ++ EE ++ G Sbjct: 65 QMADTNSDGSVSLEEYEDLIIKSLQKAGIRVEK 97 >4GJF-A nrPDB Length = 89 Score = 47.8 bits (112), Expect = 5e-06, Method: Composition-based stats. Identities = 12/82 (14%), Positives = 30/82 (36%), Gaps = 1/82 (1%) Query: 82 LQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDAD 141 ++ T+ K E ++ + F G + + + + D D Sbjct: 9 VEQLTEEQKNEFKAAFDIFVQGAEDGCISTKELGKVMRMLGQNPTPEEL-QEMIDEVDED 67 Query: 142 GNGAIHFEDFVVGLSILLRGTV 163 G+G + F++F+V + ++ Sbjct: 68 GSGTVDFDEFLVMMVRCMKDDS 89 Score = 42.0 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 19/90 (21%), Positives = 36/90 (40%), Gaps = 13/90 (14%) Query: 153 VGLSILLRGTVHEKLKWAFNLYDINK-DGCITKEEMLAIMKSIYDMMGRHTYPILREDAP 211 L + K AF+++ DGCI+ +E+ +M+ L ++ Sbjct: 6 KAAVEQLTEEQKNEFKAAFDIFVQGAEDGCISTKELGKVMRM------------LGQNPT 53 Query: 212 LEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 E ++ ++D + G V DEFL + Sbjct: 54 PEELQEMIDEVDEDGSGTVDFDEFLVMMVR 83 >1W7I-B nrPDB Length = 151 Score = 47.8 bits (112), Expect = 5e-06, Method: Composition-based stats. Identities = 27/157 (17%), Positives = 49/157 (31%), Gaps = 19/157 (12%) Query: 87 KFTKKELQSLYRGFK--NECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFN-AFDADGN 143 +F K +L+ F+ + G + + L N D + Sbjct: 3 EFNKDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELKS 62 Query: 144 GAIHFEDFVVGLSILLRGTVH---EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGR 200 + FE F+ L + + E F ++D +G + E+ R Sbjct: 63 RRVDFETFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAEL------------R 110 Query: 201 HTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLE 237 H L E E VE + +G + + FL+ Sbjct: 111 HVLTTLGEKMTEEEVETVLA-GHEDSNGCINYEAFLK 146 Score = 34.7 bits (78), Expect = 0.038, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 27/77 (35%), Gaps = 10/77 (12%) Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDR 224 E+ K AF L+D DG I + +M+++ + + K D Sbjct: 10 EEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNP----------KSDE 59 Query: 225 NQDGVVTIDEFLETCQK 241 + V + FL Q Sbjct: 60 LKSRRVDFETFLPMLQA 76 >3TZ1-A nrPDB Length = 74 Score = 47.8 bits (112), Expect = 5e-06, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 31/81 (38%), Gaps = 12/81 (14%) Query: 159 LRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERF 218 + +LK AF + D K G I + + I+KS L ++ + +E Sbjct: 1 MEDLDERELKEAFRVLDKEKKGVIKVDVLRWILKS------------LGDELTEDEIENM 48 Query: 219 FQKMDRNQDGVVTIDEFLETC 239 + D + G V +EF Sbjct: 49 IAETDTDGSGTVDYEEFKCLM 69 Score = 35.1 bits (79), Expect = 0.028, Method: Composition-based stats. Identities = 13/68 (19%), Positives = 27/68 (39%), Gaps = 2/68 (2%) Query: 88 FTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIH 147 ++EL+ +R E G++ D + I + + D DG+G + Sbjct: 4 LDERELKEAFRVLDKE-KKGVIKVDVLRWILKSLGDELTEDEI-ENMIAETDTDGSGTVD 61 Query: 148 FEDFVVGL 155 +E+F + Sbjct: 62 YEEFKCLM 69 >2HPS-A nrPDB Length = 186 Score = 47.8 bits (112), Expect = 5e-06, Method: Composition-based stats. Identities = 15/59 (25%), Positives = 28/59 (47%) Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMK 192 +++ D D +G + +F L + +K FN D NK+G I+++E L + Sbjct: 107 MYDCIDTDKDGYVSLPEFKAFLQAVGPDLTDDKAITCFNTLDFNKNGQISRDEFLVTVN 165 Score = 38.5 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 19/70 (27%), Positives = 26/70 (37%), Gaps = 1/70 (1%) Query: 102 NECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRG 161 + G V FK P A FN D + NG I ++F+V ++ L G Sbjct: 112 DTDKDGYVSLPEFKAFLQAVGPDLTDDK-AITCFNTLDFNKNGQISRDEFLVTVNDFLFG 170 Query: 162 TVHEKLKWAF 171 L AF Sbjct: 171 LEETALANAF 180 Score = 35.4 bits (80), Expect = 0.021, Method: Composition-based stats. Identities = 22/117 (18%), Positives = 39/117 (33%), Gaps = 16/117 (13%) Query: 135 FNAFDADGNGAIHFEDF------VVGLSILLRGTVHEKLKWAFNLYDINKDG---CITKE 185 D G+G I ED+ + ++ L E + + D I+ E Sbjct: 20 MQRVDVTGDGFISREDYELIAVRIAKIAKLSAEKAEETRQEFLRVADQLGLAPGVRISVE 79 Query: 186 EML-AIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 E S+ M G + + + +D ++DG V++ EF Q Sbjct: 80 EAAVNATDSLLKMKGEEKAMAVIQSLI------MYDCIDTDKDGYVSLPEFKAFLQA 130 Score = 34.7 bits (78), Expect = 0.040, Method: Composition-based stats. Identities = 15/62 (24%), Positives = 28/62 (45%), Gaps = 12/62 (19%) Query: 175 DINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDE 234 D +KDG ++ E A ++++ D + F +D N++G ++ DE Sbjct: 112 DTDKDGYVSLPEFKAFLQAVGP------------DLTDDKAITCFNTLDFNKNGQISRDE 159 Query: 235 FL 236 FL Sbjct: 160 FL 161 >3DTP-E nrPDB Length = 196 Score = 47.8 bits (112), Expect = 5e-06, Method: Composition-based stats. Identities = 27/157 (17%), Positives = 57/157 (36%), Gaps = 21/157 (13%) Query: 88 FTKKELQSLYRGF--KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGA 145 FT+ ++Q F ++ G + ++ + + + A+ G Sbjct: 51 FTQHQVQEFKEAFQLIDQDKDGFISKNDIRATFDSLGRLCTEQELDSMV-----AEAPGP 105 Query: 146 IHFEDFVVGLSILLRGTVHEKLK-WAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYP 204 I+F F+ + GT E + AFNL+D DG +E + + Sbjct: 106 INFTMFLTIFGDRIAGTDEEDVIVNAFNLFD-EGDGKCKEETLKRSL------------T 152 Query: 205 ILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 E + V++ + + +G++ I +F + K Sbjct: 153 TWGEKFSQDEVDQALSEAPIDGNGLIDIKKFAQILTK 189 Score = 36.2 bits (82), Expect = 0.015, Method: Composition-based stats. Identities = 19/89 (21%), Positives = 38/89 (42%), Gaps = 9/89 (10%) Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDR 224 ++ K AF L D +KDG I+K ++ A S+ + + +AP F + Sbjct: 57 QEFKEAFQLIDQDKDGFISKNDIRATFDSLGRLCTEQELDSMVAEAPGPINFTMFLTI-- 114 Query: 225 NQDGVVTIDEFLETCQKDENIMNSMQLFE 253 + + +++ I+N+ LF+ Sbjct: 115 -------FGDRIAGTDEEDVIVNAFNLFD 136 >3PAT-A nrPDB Length = 110 Score = 47.4 bits (111), Expect = 5e-06, Method: Composition-based stats. Identities = 25/117 (21%), Positives = 44/117 (37%), Gaps = 12/117 (10%) Query: 126 DATTYAHFLFNAFDA-DGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITK 184 A + A DA G+ + + F + L+ +K F D + G I + Sbjct: 4 KDLLKADDIKKALDAVKAEGSFNHKKFFALVG--LKAMSANDVKKVFKAIDADASGFIEE 61 Query: 185 EEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 EE+ ++KS + D + F + D++ DG + IDEF + Sbjct: 62 EELKFVLKS---------FAADGRDLTDAETKAFLKAADKDGDGKIGIDEFETLVHE 109 Score = 30.8 bits (68), Expect = 0.57, Method: Composition-based stats. Identities = 15/77 (19%), Positives = 32/77 (41%), Gaps = 3/77 (3%) Query: 82 LQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAH--FLFNAFD 139 L + +++ +++ + +G ++E+ K + F G T A A D Sbjct: 33 LVGLKAMSANDVKKVFKA-IDADASGFIEEEELKFVLKSFAADGRDLTDAETKAFLKAAD 91 Query: 140 ADGNGAIHFEDFVVGLS 156 DG+G I ++F + Sbjct: 92 KDGDGKIGIDEFETLVH 108 >4NSC-A nrPDB Length = 401 Score = 47.4 bits (111), Expect = 6e-06, Method: Composition-based stats. Identities = 35/209 (16%), Positives = 69/209 (33%), Gaps = 31/209 (14%) Query: 62 SSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTG----LVDEDTFKLI 117 + + + S R + + + + T ++ + K G + + F Sbjct: 21 MEEKKKKRSGFRDRKVMEYENRIRAYSTPDKIFRYFATLKVISEPGEAEVFMTPEDFVRS 80 Query: 118 YSQFFPQGDATTYAHFLFNAFDADG--------------------NGAIHFEDFVVGLSI 157 + Q + ++ FD G I F D++ ++ Sbjct: 81 ITPNEKQPEHLGLDQYIIKRFDGKKISQEREKFADEGSIFYTLGECGLISFSDYIFLTTV 140 Query: 158 LLRGTVHEKLKWAFNLYDINKDGCITKEE---MLAIMKSIYDMMGRHTYPILREDAPLEH 214 L T + AF ++D+N DG + EE + +I++S M RH + Sbjct: 141 LS--TPQRNFEIAFKMFDLNGDGEVDMEEFEQVQSIIRSQTSMGMRHRDRPTTGNTLKSG 198 Query: 215 VERFFQ--KMDRNQDGVVTIDEFLETCQK 241 + + G +TI FLE +K Sbjct: 199 LCSALTTYFFGADLKGKLTIKNFLEFQRK 227 Score = 28.9 bits (63), Expect = 2.0, Method: Composition-based stats. Identities = 12/31 (38%), Positives = 18/31 (58%), Gaps = 1/31 (3%) Query: 132 HFLFNAFDADGNGAIHFEDFVVGL-SILLRG 161 +F FD DGNG + ++FV + L+RG Sbjct: 339 DVVFALFDCDGNGELSNKEFVSIMKQRLMRG 369 Score = 27.0 bits (58), Expect = 8.8, Method: Composition-based stats. Identities = 8/22 (36%), Positives = 16/22 (72%) Query: 171 FNLYDINKDGCITKEEMLAIMK 192 F L+D + +G ++ +E ++IMK Sbjct: 342 FALFDCDGNGELSNKEFVSIMK 363 >3KPX-A nrPDB Length = 198 Score = 47.0 bits (110), Expect = 7e-06, Method: Composition-based stats. Identities = 14/59 (23%), Positives = 26/59 (44%) Query: 131 AHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLA 189 +F+ FD DG+G+I +++ I E + F D++ G + +EM Sbjct: 118 GEAVFDIFDKDGSGSISLDEWKTYGGISGICPSDEDAEKTFKHCDLDNSGKLDVDEMTR 176 Score = 38.5 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 28/155 (18%), Positives = 48/155 (30%), Gaps = 32/155 (20%) Query: 100 FKNECPTGLVDEDTFK-----LIYSQFFPQGDATTYAHFLFNAFDA----DGNGAIHFED 150 F + G + D I ++ T AF D + F Sbjct: 31 FLDINGNGKITLDEIVSKASDDICAKLGATPAQTQRHQEAVEAFFKKIGLDYGKEVEFPA 90 Query: 151 FVVG--------LSILLRGTVHEKLKW---AFNLYDINKDGCITKEEMLAIMKSIYDMMG 199 FV G L + + W F+++D + G I+ +E K+ + G Sbjct: 91 FVNGWKELAKHDLKLWSQNKKSLIRNWGEAVFDIFDKDGSGSISLDE----WKTYGGISG 146 Query: 200 RHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDE 234 E E+ F+ D + G + +DE Sbjct: 147 IC--------PSDEDAEKTFKHCDLDNSGKLDVDE 173 Score = 35.4 bits (80), Expect = 0.025, Method: Composition-based stats. Identities = 20/71 (28%), Positives = 33/71 (46%), Gaps = 2/71 (2%) Query: 168 KWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQD 227 K+ FN DIN +G IT +E+ + K+ D+ + + E VE FF+K+ + Sbjct: 26 KFMFNFLDINGNGKITLDEI--VSKASDDICAKLGATPAQTQRHQEAVEAFFKKIGLDYG 83 Query: 228 GVVTIDEFLET 238 V F+ Sbjct: 84 KEVEFPAFVNG 94 Score = 34.7 bits (78), Expect = 0.045, Method: Composition-based stats. Identities = 21/114 (18%), Positives = 41/114 (35%), Gaps = 13/114 (11%) Query: 133 FLFNAFDADGNGAIHFEDFVVGLS---------ILLRGTVHEKLKWAFNLYDINKDGCIT 183 F+FN D +GNG I ++ V S + H++ AF + Sbjct: 27 FMFNFLDINGNGKITLDEIVSKASDDICAKLGATPAQTQRHQEAVEAF--FKKIGLDYGK 84 Query: 184 KEEMLAIMKSIYDMMGRHTYP--ILREDAPLEHVERFFQKMDRNQDGVVTIDEF 235 + E A + ++ ++ E F D++ G +++DE+ Sbjct: 85 EVEFPAFVNGWKELAKHDLKLWSQNKKSLIRNWGEAVFDIFDKDGSGSISLDEW 138 Score = 28.1 bits (61), Expect = 4.2, Method: Composition-based stats. Identities = 8/25 (32%), Positives = 13/25 (52%) Query: 218 FFQKMDRNQDGVVTIDEFLETCQKD 242 F +D N +G +T+DE + D Sbjct: 28 MFNFLDINGNGKITLDEIVSKASDD 52 >5XOP-A nrPDB Length = 66 Score = 47.0 bits (110), Expect = 7e-06, Method: Composition-based stats. Identities = 19/65 (29%), Positives = 28/65 (43%) Query: 130 YAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLA 189 A LF D +G+GA+ +E+ +S + L+ F D + DG I EE Sbjct: 1 MAEALFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDKDGDGFIDFEEFAK 60 Query: 190 IMKSI 194 SI Sbjct: 61 FYGSI 65 Score = 43.5 bits (101), Expect = 9e-05, Method: Composition-based stats. Identities = 14/69 (20%), Positives = 30/69 (43%), Gaps = 12/69 (17%) Query: 170 AFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGV 229 F D+N DG ++ EE+ A + + + ++ F+ +D++ DG Sbjct: 5 LFKEIDVNGDGAVSYEEVKAFVSKKRAIKN------------EQLLQLIFKSIDKDGDGF 52 Query: 230 VTIDEFLET 238 + +EF + Sbjct: 53 IDFEEFAKF 61 Score = 35.8 bits (81), Expect = 0.021, Method: Composition-based stats. Identities = 13/49 (26%), Positives = 20/49 (40%), Gaps = 1/49 (2%) Query: 105 PTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVV 153 G V + K S+ + +F + D DG+G I FE+F Sbjct: 13 GDGAVSYEEVKAFVSKKRAIKNEQLL-QLIFKSIDKDGDGFIDFEEFAK 60 Score = 30.4 bits (67), Expect = 0.77, Method: Composition-based stats. Identities = 10/32 (31%), Positives = 15/32 (46%) Query: 214 HVERFFQKMDRNQDGVVTIDEFLETCQKDENI 245 E F+++D N DG V+ +E K I Sbjct: 1 MAEALFKEIDVNGDGAVSYEEVKAFVSKKRAI 32 >1O1A-B nrPDB Length = 145 Score = 47.0 bits (110), Expect = 8e-06, Method: Composition-based stats. Identities = 19/129 (14%), Positives = 45/129 (34%), Gaps = 7/129 (5%) Query: 88 FTKKELQSLYRGFK--NECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGA 145 F + E++ F ++ G++D+D + ++ + +G Sbjct: 1 FDETEIEDFKEAFTVIDQNADGIIDKDDLRETFAAMGRLNVKNEELDAMIKE----ASGP 56 Query: 146 IHFEDFVVGLSILLRG-TVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYP 204 I+F F+ L+G + + AF + D + G I K + ++ + Sbjct: 57 INFTVFLTMFGEKLKGADPEDVIMGAFKVLDPDGKGSIKKSFLEELLTTGGGRFTPEEIK 116 Query: 205 ILREDAPLE 213 + P + Sbjct: 117 NMWAAFPPD 125 Score = 35.8 bits (81), Expect = 0.020, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 28/74 (37%), Gaps = 15/74 (20%) Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDR 224 E K AF + D N DG I K+++ ++ + ++ E ++ ++ Sbjct: 7 EDFKEAFTVIDQNADGIIDKDDLRETFAAMGRLNVKN-----------EELDAMIKEA-- 53 Query: 225 NQDGVVTIDEFLET 238 G + FL Sbjct: 54 --SGPINFTVFLTM 65 >1SR6-C nrPDB Length = 156 Score = 47.0 bits (110), Expect = 8e-06, Method: Composition-based stats. Identities = 23/107 (21%), Positives = 43/107 (40%), Gaps = 18/107 (16%) Query: 142 GNGAIHFEDFV---VGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMM 198 G ++ FE+F+ GL +GT + + AF +D G I+ E+ ++ + Sbjct: 59 GEKSLPFEEFLPAYEGLMDCEQGTFADYM-EAFKTFDREGQGFISGAELRHVLTA----- 112 Query: 199 GRHTYPILREDAPLEHVERFFQKMDRNQD--GVVTIDEFLETCQKDE 243 L E E V+ + D +D G V ++F++ Sbjct: 113 -------LGERLSDEDVDEIIKLTDLQEDLEGNVKYEDFVKKVMAGP 152 Score = 28.5 bits (62), Expect = 2.8, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 27/70 (38%), Gaps = 3/70 (4%) Query: 112 DTFKLIYSQFFPQGDATTYAHFL--FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKW 169 + F Y + T+A ++ F FD +G G I + L+ L E + Sbjct: 66 EEFLPAYEGLM-DCEQGTFADYMEAFKTFDREGQGFISGAELRHVLTALGERLSDEDVDE 124 Query: 170 AFNLYDINKD 179 L D+ +D Sbjct: 125 IIKLTDLQED 134 >1ZMZ-A nrPDB Length = 98 Score = 47.0 bits (110), Expect = 8e-06, Method: Composition-based stats. Identities = 15/81 (18%), Positives = 35/81 (43%), Gaps = 12/81 (14%) Query: 159 LRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERF 218 L ++++ AF+L+D + G I +E+ M++ L + E +++ Sbjct: 25 LTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRA------------LGFEPKKEEIKKM 72 Query: 219 FQKMDRNQDGVVTIDEFLETC 239 ++D+ G + +FL Sbjct: 73 ISEIDKEGTGKMNFGDFLTVM 93 Score = 39.7 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 13/76 (17%), Positives = 31/76 (40%), Gaps = 3/76 (3%) Query: 87 KFTKKELQSLYRGFK--NECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNG 144 + T+++ Q + F + TG +D K+ + + + D +G G Sbjct: 24 ELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEEIK-KMISEIDKEGTG 82 Query: 145 AIHFEDFVVGLSILLR 160 ++F DF+ ++ + Sbjct: 83 KMNFGDFLTVMTQKMS 98 Score = 36.6 bits (83), Expect = 0.012, Method: Composition-based stats. Identities = 16/57 (28%), Positives = 26/57 (45%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIM 191 F+ FDADG G I ++ V + L E++K + D G + + L +M Sbjct: 37 FDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVM 93 >1I84-U nrPDB Length = 166 Score = 47.0 bits (110), Expect = 8e-06, Method: Composition-based stats. Identities = 19/129 (14%), Positives = 45/129 (34%), Gaps = 7/129 (5%) Query: 88 FTKKELQSLYRGFK--NECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGA 145 F + E++ F ++ G++D+D + ++ + +G Sbjct: 19 FDETEIEDFKEAFTVIDQNADGIIDKDDLRETFAAMGRLNVKNEELDAMIKE----ASGP 74 Query: 146 IHFEDFVVGLSILLRG-TVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYP 204 I+F F+ L+G + + AF + D + G I K + ++ + Sbjct: 75 INFTVFLTMFGEKLKGADPEDVIMGAFKVLDPDGKGSIKKSFLEELLTTGGGRFTPEEIK 134 Query: 205 ILREDAPLE 213 + P + Sbjct: 135 NMWAAFPPD 143 Score = 35.8 bits (81), Expect = 0.021, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 28/74 (37%), Gaps = 15/74 (20%) Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDR 224 E K AF + D N DG I K+++ ++ + ++ E ++ ++ Sbjct: 25 EDFKEAFTVIDQNADGIIDKDDLRETFAAMGRLNVKN-----------EELDAMIKEA-- 71 Query: 225 NQDGVVTIDEFLET 238 G + FL Sbjct: 72 --SGPINFTVFLTM 83 Score = 27.0 bits (58), Expect = 8.2, Method: Composition-based stats. Identities = 17/96 (17%), Positives = 36/96 (37%), Gaps = 2/96 (2%) Query: 106 TGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGT-VH 164 +G ++ F ++ + D F D DG G+I + F+ L G Sbjct: 72 SGPINFTVFLTMFGEKLKGADPEDVIMGAFKVLDPDGKGSIK-KSFLEELLTTGGGRFTP 130 Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGR 200 E++K + + + G + + + ++ D G Sbjct: 131 EEIKNMWAAFPPDVAGNVDYKNICYVITHGEDAEGE 166 >2MA2-A nrPDB Length = 81 Score = 46.6 bits (109), Expect = 1e-05, Method: Composition-based stats. Identities = 21/71 (29%), Positives = 33/71 (46%), Gaps = 7/71 (9%) Query: 129 TYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEML 188 +F FD DG+G I E+F + + AF D N+DGCI++EEM+ Sbjct: 13 KMVESVFRNFDVDGDGHISQEEFQIIRGNFPYLS-------AFGDLDQNQDGCISREEMV 65 Query: 189 AIMKSIYDMMG 199 + ++G Sbjct: 66 SYFLRSSSVLG 76 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 15/86 (17%), Positives = 38/86 (44%), Gaps = 19/86 (22%) Query: 161 GTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQ 220 + + ++ F +D++ DG I++EE I++ + + F Sbjct: 9 EHIEKMVESVFRNFDVDGDGHISQEE-FQIIRGNFPYLS------------------AFG 49 Query: 221 KMDRNQDGVVTIDEFLETCQKDENIM 246 +D+NQDG ++ +E + + +++ Sbjct: 50 DLDQNQDGCISREEMVSYFLRSSSVL 75 >4NQG-A nrPDB Length = 197 Score = 46.6 bits (109), Expect = 1e-05, Method: Composition-based stats. Identities = 13/61 (21%), Positives = 27/61 (44%) Query: 129 TYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEML 188 + LF+ D DGNG++ ++++ + + F D++ DG + +EM Sbjct: 114 LWGDALFDIIDKDGNGSVSLDEWIQYTHCAGIQQSRGQCEATFAHCDLDGDGKLDVDEMT 173 Query: 189 A 189 Sbjct: 174 R 174 Score = 37.0 bits (84), Expect = 0.008, Method: Composition-based stats. Identities = 22/156 (14%), Positives = 46/156 (29%), Gaps = 34/156 (21%) Query: 100 FKNECPTGLVDEDTFK----LIYSQFFPQGDATTYAHFLFNAFDADGNGAIHF------E 149 F + G ++ + I + + T H D G + + Sbjct: 29 FLDINSNGQINLNEMVHKASNIICKKLGATEEQTRRHQKCVE-DFFGGAGLEYDKDTTWP 87 Query: 150 DFVVGLSILLRGTVHEKLKW-----------AFNLYDINKDGCITKEEMLAIMKSIYDMM 198 +++ G L + + K F++ D + +G ++ +E + Sbjct: 88 EYIEGWKRLAKTELERHSKNRVTLIRLWGDALFDIIDKDGNGSVSLDEWIQYTHCAGIQQ 147 Query: 199 GRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDE 234 R E F D + DG + +DE Sbjct: 148 SRG------------QCEATFAHCDLDGDGKLDVDE 171 Score = 34.3 bits (77), Expect = 0.052, Method: Composition-based stats. Identities = 20/119 (16%), Positives = 42/119 (35%), Gaps = 13/119 (10%) Query: 133 FLFNAFDADGNGAIHFEDFVVGLSILL---RGTVHEKLKWAFN-LYDINKDGCITKEEML 188 +FN D + NG I+ + V S ++ G E+ + + D + + Sbjct: 25 HMFNFLDINSNGQINLNEMVHKASNIICKKLGATEEQTRRHQKCVEDFFGGAGLEYD--K 82 Query: 189 AIMKSIYDMMGRHTYPILREDAPLEHV-------ERFFQKMDRNQDGVVTIDEFLETCQ 240 Y + E V + F +D++ +G V++DE+++ Sbjct: 83 DTTWPEYIEGWKRLAKTELERHSKNRVTLIRLWGDALFDIIDKDGNGSVSLDEWIQYTH 141 >3SIA-A nrPDB Length = 220 Score = 46.2 bits (108), Expect = 1e-05, Method: Composition-based stats. Identities = 22/121 (18%), Positives = 49/121 (40%), Gaps = 15/121 (12%) Query: 91 KELQSLYRGFK--NECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHF 148 + +Y+ F + +G ++ + + + T A + FD D NG I F Sbjct: 48 DQYTRIYQWFMGVDRDRSGTLEINELMMGQFPGGIRLSPQT-ALRMMRIFDTDFNGHISF 106 Query: 149 EDFVVGLSILLRGTVHEKLKWAFNLYDIN---KDGCITKEEMLAIMKSIYDMMGRHTYPI 205 +F+ ++ A+NL+ +N + G + E+L ++ + + + T + Sbjct: 107 YEFMAMYKF---------MELAYNLFVMNARARSGTLEPHEILPALQQLGFYINQRTSLL 157 Query: 206 L 206 L Sbjct: 158 L 158 Score = 33.1 bits (74), Expect = 0.11, Method: Composition-based stats. Identities = 9/66 (13%), Positives = 22/66 (33%), Gaps = 12/66 (18%) Query: 175 DINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDE 234 D ++ G + E++ + T R + D + +G ++ E Sbjct: 61 DRDRSGTLEINELMMGQFPGGIRLSPQTAL------------RMMRIFDTDFNGHISFYE 108 Query: 235 FLETCQ 240 F+ + Sbjct: 109 FMAMYK 114 Score = 31.6 bits (70), Expect = 0.32, Method: Composition-based stats. Identities = 16/100 (16%), Positives = 33/100 (33%), Gaps = 11/100 (11%) Query: 122 FPQGDATTYAHFL-----FNAFDADGNGAIHFEDFVVGLSILLRG---TVHEKLKWAFNL 173 FP + + F D D +G + + + + G + L+ + Sbjct: 39 FPLLNTIPLDQYTRIYQWFMGVDRDRSGTLEINE--LMMGQFPGGIRLSPQTALRMM-RI 95 Query: 174 YDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLE 213 +D + +G I+ E +A+ K + LE Sbjct: 96 FDTDFNGHISFYEFMAMYKFMELAYNLFVMNARARSGTLE 135 >1RTP-1 nrPDB Length = 109 Score = 46.2 bits (108), Expect = 1e-05, Method: Composition-based stats. Identities = 17/99 (17%), Positives = 40/99 (40%), Gaps = 11/99 (11%) Query: 144 GAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTY 203 + + F + L+ + +K F++ D +K G I ++E+ +I+K + Sbjct: 22 DSFDHKKFFQMVG--LKKKSADDVKKVFHILDKDKSGFIEEDELGSILKG---------F 70 Query: 204 PILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKD 242 D + + D++ DG + ++EF + Sbjct: 71 SSDARDLSAKETKTLMAAGDKDGDGKIGVEEFSTLVAES 109 Score = 34.3 bits (77), Expect = 0.049, Method: Composition-based stats. Identities = 15/80 (18%), Positives = 26/80 (32%), Gaps = 3/80 (3%) Query: 115 KLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLY 174 K + + + +F+ D D +G I ++ L K L Sbjct: 27 KKFFQMVGLKKKSADDVKKVFHILDKDKSGFIEEDELGSILKGFSSDARDLSAKETKTLM 86 Query: 175 ---DINKDGCITKEEMLAIM 191 D + DG I EE ++ Sbjct: 87 AAGDKDGDGKIGVEEFSTLV 106 Score = 29.7 bits (65), Expect = 1.2, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 24/58 (41%), Gaps = 2/58 (3%) Query: 101 KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHF--LFNAFDADGNGAIHFEDFVVGLS 156 ++ +G ++ED I F + L A D DG+G I E+F ++ Sbjct: 50 LDKDKSGFIEEDELGSILKGFSSDARDLSAKETKTLMAAGDKDGDGKIGVEEFSTLVA 107 >3AKA-A nrPDB Length = 166 Score = 46.2 bits (108), Expect = 1e-05, Method: Composition-based stats. Identities = 30/154 (19%), Positives = 48/154 (31%), Gaps = 35/154 (22%) Query: 102 NECPTGLVDEDTF----KLIYSQFFP----------QGDATTYAHFLFNAFDADGNGAIH 147 ++ G +D F K + ++F G A L D DG+ I Sbjct: 14 DQDGNGHIDRSDFSGAAKALLAEFGVAARSDRGQALYGGAEALWQGLAGIADRDGDQRIT 73 Query: 148 FEDFVVGLSILLRGTVHE-------KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGR 200 E+FV G LR L A + D + DG +T + + + Sbjct: 74 REEFVTGAVKRLRDKPDRFAEIARPFLHAALGVADTDGDGAVTVADTARALTAFGV---- 129 Query: 201 HTYPILREDAPLEHVERFFQKMDRNQDGVVTIDE 234 P + + +D + DG V E Sbjct: 130 ----------PEDLARQAAAALDTDGDGKVGETE 153 Score = 42.8 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 15/82 (18%), Positives = 30/82 (36%), Gaps = 5/82 (6%) Query: 164 HEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQK-- 221 ++ F +D + +G I + + K++ G + E +Q Sbjct: 3 ERRIAARFTTFDQDGNGHIDRSDFSGAAKALLAEFGVAARSDRGQAL-YGGAEALWQGLA 61 Query: 222 --MDRNQDGVVTIDEFLETCQK 241 DR+ D +T +EF+ K Sbjct: 62 GIADRDGDQRITREEFVTGAVK 83 Score = 37.4 bits (85), Expect = 0.007, Method: Composition-based stats. Identities = 25/112 (22%), Positives = 34/112 (30%), Gaps = 20/112 (17%) Query: 135 FNAFDADGNGAIHFEDFVVGLSIL---------------LRGTVHEKLKWAFNLYDINKD 179 F FD DGNG I DF L L G + + D + D Sbjct: 10 FTTFDQDGNGHIDRSDFSGAAKALLAEFGVAARSDRGQALYGGAEALWQGLAGIADRDGD 69 Query: 180 GCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVT 231 IT+EE + + P + + D + DG VT Sbjct: 70 QRITREEFV-----TGAVKRLRDKPDRFAEIARPFLHAALGVADTDGDGAVT 116 Score = 35.1 bits (79), Expect = 0.032, Method: Composition-based stats. Identities = 17/92 (18%), Positives = 32/92 (34%), Gaps = 8/92 (8%) Query: 102 NECPTGLVDEDTFKL-IYSQFFPQGD-----ATTYAHFLFNAFDADGNGAIHFEDFVVGL 155 + + + F + + D A + H D DG+GA+ D L Sbjct: 65 DRDGDQRITREEFVTGAVKRLRDKPDRFAEIARPFLHAALGVADTDGDGAVTVADTARAL 124 Query: 156 SILLRGTVHEKLKWAFNLYDINKDGCITKEEM 187 + G + + A D + DG + + E+ Sbjct: 125 TAF--GVPEDLARQAAAALDTDGDGKVGETEI 154 >1QX2-A nrPDB Length = 76 Score = 46.2 bits (108), Expect = 2e-05, Method: Composition-based stats. Identities = 20/85 (23%), Positives = 42/85 (49%), Gaps = 18/85 (21%) Query: 162 TVHEKLKWAFNLY-----DINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVE 216 E++K AF ++ D N+ I+KEE+ +M+++ + + ++ Sbjct: 2 KSPEEIKGAFEVFAAKEGDPNQ---ISKEELKLVMQTLGPSLLKGMST----------LD 48 Query: 217 RFFQKMDRNQDGVVTIDEFLETCQK 241 +++D+N DG V+ +EFL +K Sbjct: 49 EMIEEVDKNGDGEVSFEEFLVMMKK 73 Score = 39.7 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 13/74 (17%), Positives = 32/74 (43%), Gaps = 2/74 (2%) Query: 89 TKKELQSLYRGFK-NECPTGLVDEDTFKLIYSQFFPQG-DATTYAHFLFNAFDADGNGAI 146 + +E++ + F E + ++ KL+ P + + D +G+G + Sbjct: 3 SPEEIKGAFEVFAAKEGDPNQISKEELKLVMQTLGPSLLKGMSTLDEMIEEVDKNGDGEV 62 Query: 147 HFEDFVVGLSILLR 160 FE+F+V + + + Sbjct: 63 SFEEFLVMMKKISQ 76 >1JF0-A nrPDB Length = 195 Score = 45.8 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 14/59 (23%), Positives = 25/59 (42%) Query: 131 AHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLA 189 +F+ FD DG+G I +++ I E + F D++ G + +EM Sbjct: 115 GDAVFDIFDKDGSGTITLDEWKAYGRISGISPSEEDCEKTFQHCDLDNSGELDVDEMTR 173 Score = 33.1 bits (74), Expect = 0.13, Method: Composition-based stats. Identities = 21/113 (18%), Positives = 39/113 (34%), Gaps = 11/113 (9%) Query: 133 FLFNAFDADGNGAIHFEDFV--------VGLSILLRGTVHEK--LKWAFNLYDINKDGCI 182 F+F+ D +GNG I ++ V L T + ++ F + Sbjct: 24 FMFDYLDINGNGQITLDEIVSKASDDICKNLGATPAQTQRHQDCVEAFFRGCGLEYGKET 83 Query: 183 TKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEF 235 E L K++ + E + F D++ G +T+DE+ Sbjct: 84 KFPEFLEGWKNLANADLAKWARNEP-TLIREWGDAVFDIFDKDGSGTITLDEW 135 Score = 28.9 bits (63), Expect = 2.2, Method: Composition-based stats. Identities = 8/32 (25%), Positives = 18/32 (56%), Gaps = 2/32 (6%) Query: 218 FFQKMDRNQDGVVTIDEFLETCQKDENIMNSM 249 F +D N +G +T+DE + + ++I ++ Sbjct: 25 MFDYLDINGNGQITLDEIVS--KASDDICKNL 54 Score = 28.1 bits (61), Expect = 3.3, Method: Composition-based stats. Identities = 19/71 (26%), Positives = 30/71 (42%), Gaps = 2/71 (2%) Query: 168 KWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQD 227 K+ F+ DIN +G IT +E+ + K+ D+ + + VE FF+ Sbjct: 23 KFMFDYLDINGNGQITLDEI--VSKASDDICKNLGATPAQTQRHQDCVEAFFRGCGLEYG 80 Query: 228 GVVTIDEFLET 238 EFLE Sbjct: 81 KETKFPEFLEG 91 >1RK9-A nrPDB Length = 110 Score = 45.8 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 18/99 (18%), Positives = 39/99 (39%), Gaps = 11/99 (11%) Query: 144 GAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTY 203 + + F + L+ + +K F++ D +K G I ++E+ I+K + Sbjct: 23 DSFDHKKFFQMVG--LKKKSADDVKKVFHMLDKDKSGFIEEDELGFILKG---------F 71 Query: 204 PILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKD 242 D + + D++ DG + +DEF + Sbjct: 72 SPDARDLSAKETKMLMAAGDKDGDGKIGVDEFSTLVAES 110 Score = 32.4 bits (72), Expect = 0.21, Method: Composition-based stats. Identities = 15/80 (18%), Positives = 30/80 (37%), Gaps = 3/80 (3%) Query: 115 KLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDF---VVGLSILLRGTVHEKLKWAF 171 K + + + +F+ D D +G I ++ + G S R ++ K Sbjct: 28 KKFFQMVGLKKKSADDVKKVFHMLDKDKSGFIEEDELGFILKGFSPDARDLSAKETKMLM 87 Query: 172 NLYDINKDGCITKEEMLAIM 191 D + DG I +E ++ Sbjct: 88 AAGDKDGDGKIGVDEFSTLV 107 Score = 31.2 bits (69), Expect = 0.43, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 25/58 (43%), Gaps = 2/58 (3%) Query: 101 KNECPTGLVDEDTFKLIYSQFFPQGDATTYAH--FLFNAFDADGNGAIHFEDFVVGLS 156 ++ +G ++ED I F P + L A D DG+G I ++F ++ Sbjct: 51 LDKDKSGFIEEDELGFILKGFSPDARDLSAKETKMLMAAGDKDGDGKIGVDEFSTLVA 108 >6EAZ-A nrPDB Length = 379 Score = 45.8 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 20/122 (16%), Positives = 45/122 (36%), Gaps = 9/122 (7%) Query: 139 DADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMM 198 D G I + +++ L+IL + H AF + D++ + I ++E + + K I Sbjct: 95 DLGDKGVISYTEYLFLLTILTK--PHSGFHVAFKMLDVDGNEMIERKEFVKLQKIISKQD 152 Query: 199 GRHTYPILREDAPLEHVER-------FFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQL 251 G T + V+ + + + + EF + + + M+ Sbjct: 153 GFKTVKTNETEYQDPTVKEPGVNTTLQVRFFGKRGEKKLHYKEFRRFMENLQTEVQEMEF 212 Query: 252 FE 253 + Sbjct: 213 LQ 214 Score = 36.2 bits (82), Expect = 0.013, Method: Composition-based stats. Identities = 21/110 (19%), Positives = 43/110 (39%), Gaps = 8/110 (7%) Query: 87 KFTKKELQSLY-RGFKNECPTG-LVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNG 144 FT E + +Y R + + G + D FK F + A +F+ Sbjct: 233 FFTNTENKDIYWRNVREKLSVGESISLDEFKSFCH-FTTHLEDFAIAMQMFSLAHRP--- 288 Query: 145 AIHFEDFVVGLSI-LLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS 193 + +F + + + L F ++D++ D C++ E L ++K+ Sbjct: 289 -VRLAEFKRAVKVATGQELSDNLLDTVFKIFDLDGDECLSHGEFLGVLKN 337 >1QXP-A nrPDB Length = 900 Score = 45.5 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 24/198 (12%), Positives = 64/198 (32%), Gaps = 28/198 (14%) Query: 65 SELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRG-FKNECPTGL-VDEDTFKLIY---- 118 SE + T + L + +++E+ ++ F + + + I Sbjct: 504 SEKKAGTQELDDQIQANLPDEKVLSEEEIDDNFKTLFSKLAGDDMEISVKELQTILNRII 563 Query: 119 ---SQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYD 175 G + + N D DGNG + +F + + + F +D Sbjct: 564 SKHKDLRTNGFSLESCRSMVNLMDRDGNGKLGLVEFNILWNRIRNYLT------IFRKFD 617 Query: 176 INKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEF 235 ++K G ++ EM +++ + + ++ + + ++ D F Sbjct: 618 LDKSGSMSAYEMRMAIEAAGFKLPCQLHQVIVARFADDEL-------------IIDFDNF 664 Query: 236 LETCQKDENIMNSMQLFE 253 + + E + + + Sbjct: 665 VRCLVRLEILFKIFKQLD 682 Score = 40.4 bits (93), Expect = 8e-04, Method: Composition-based stats. Identities = 24/131 (18%), Positives = 45/131 (34%), Gaps = 7/131 (5%) Query: 126 DATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFN-LYDI--NKDGCI 182 + FL F G +D + + E++ F L+ D I Sbjct: 491 EPNKEGDFLLRFFSEKKAGTQELDDQIQANLPDEKVLSEEEIDDNFKTLFSKLAGDDMEI 550 Query: 183 TKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKD 242 + +E+ I+ I + +H LE MDR+ +G + + EF + Sbjct: 551 SVKELQTILNRI---ISKHKDLRTNG-FSLESCRSMVNLMDRDGNGKLGLVEFNILWNRI 606 Query: 243 ENIMNSMQLFE 253 N + + F+ Sbjct: 607 RNYLTIFRKFD 617 Score = 38.5 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 20/127 (15%), Positives = 47/127 (37%), Gaps = 25/127 (19%) Query: 132 HFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIM 191 + D+D G + FE+F + + +K + + ++ ++ G I E+ Sbjct: 777 RSMVAVMDSDTTGKLGFEEFKYLWNNI------KKWQGIYKRFETDRSGTIGSNELPGAF 830 Query: 192 KSIYDMMGRHTYPILREDAPLE--------------HVERFFQKM---DRNQDGVV--TI 232 ++ + +H Y ++ E ++ F+ D+N G + I Sbjct: 831 EAAGFHLNQHIYSMIIRRYSDETGNMDFDNFISCLVRLDAMFRAFRSLDKNGTGQIQVNI 890 Query: 233 DEFLETC 239 E+L+ Sbjct: 891 QEWLQLT 897 >2KQY-A nrPDB Length = 108 Score = 45.5 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 16/98 (16%), Positives = 39/98 (39%), Gaps = 11/98 (11%) Query: 144 GAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTY 203 + +++ F + + + +++K F + D +K G I +EE+ +K+ + Sbjct: 22 DSFNYKSFFSTVGLSSKTP--DQIKKVFGILDQDKSGFIEEEELQLFLKN---------F 70 Query: 204 PILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 + F D + DG + ++EF + Sbjct: 71 SSSARVLTSAETKAFLAAGDTDGDGKIGVEEFQSLVKA 108 Score = 32.0 bits (71), Expect = 0.24, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 30/65 (46%), Gaps = 3/65 (4%) Query: 89 TKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAH--FLFNAFDADGNGAI 146 T +++ ++ G ++ +G ++E+ +L F T A A D DG+G I Sbjct: 39 TPDQIKKVF-GILDQDKSGFIEEEELQLFLKNFSSSARVLTSAETKAFLAAGDTDGDGKI 97 Query: 147 HFEDF 151 E+F Sbjct: 98 GVEEF 102 >5E1J-A nrPDB Length = 741 Score = 45.5 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 23/97 (23%), Positives = 40/97 (41%), Gaps = 10/97 (10%) Query: 148 FEDFVVGLSILLRGTVHEK---LKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYP 204 ++ F L+ + G K L+ AF L D +K+G I K + + + + + T Sbjct: 305 YDSFKEQLAKQVSGMDQMKRRMLEKAFGLIDSDKNGEIDKNQCIKLFEQL-------TNY 357 Query: 205 ILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 E F ++D +D + DEF + CQ Sbjct: 358 RTLPKISKEEFGLIFDELDDTRDFKINKDEFADLCQA 394 Score = 36.2 bits (82), Expect = 0.014, Method: Composition-based stats. Identities = 23/108 (21%), Positives = 36/108 (33%), Gaps = 7/108 (6%) Query: 112 DTFKLIYSQFFPQGDATT--YAHFLFNAFDADGNGAIHFEDFVVGLS-----ILLRGTVH 164 D+FK ++ D F D+D NG I + L Sbjct: 306 DSFKEQLAKQVSGMDQMKRRMLEKAFGLIDSDKNGEIDKNQCIKLFEQLTNYRTLPKISK 365 Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPL 212 E+ F+ D +D I K+E + ++I + P L E P Sbjct: 366 EEFGLIFDELDDTRDFKINKDEFADLCQAIALRFQKEEVPSLFEHFPQ 413 >5H53-C nrPDB Length = 153 Score = 45.5 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 24/157 (15%), Positives = 46/157 (29%), Gaps = 19/157 (12%) Query: 87 KFTKKELQSLYRGFK--NECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNG 144 +F+K++ F + + + L N + + N Sbjct: 4 EFSKEQQDEFKEAFLLYDRTGDSKITLSQVGDVLRALGTNPTNAEVKKVLGNPSNEEMNA 63 Query: 145 A-IHFEDFVVGLSILLRGTVH---EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGR 200 I FE F+ L + E ++D +G + E+ R Sbjct: 64 KKIEFEQFLPMLQAISNNKDQGTYEDFVEGLRVFDKEGNGTVMGAEL------------R 111 Query: 201 HTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLE 237 H L E E VE + +G + + F++ Sbjct: 112 HVLATLGEKMKEEEVEALMA-GQEDSNGCINYEAFVK 147 Score = 35.8 bits (81), Expect = 0.020, Method: Composition-based stats. Identities = 15/86 (17%), Positives = 34/86 (39%), Gaps = 9/86 (10%) Query: 164 HEKLKWAFNLYDINKDGCITKEEMLAIMKSIY-DMMGRHTYPILREDAPLEHVERFFQ-- 220 ++ K AF LYD D IT ++ +++++ + +L + E + + Sbjct: 10 QDEFKEAFLLYDRTGDSKITLSQVGDVLRALGTNPTNAEVKKVLGNPSNEEMNAKKIEFE 69 Query: 221 ------KMDRNQDGVVTIDEFLETCQ 240 + N T ++F+E + Sbjct: 70 QFLPMLQAISNNKDQGTYEDFVEGLR 95 >2K7B-A nrPDB Length = 76 Score = 45.5 bits (106), Expect = 3e-05, Method: Composition-based stats. Identities = 19/75 (25%), Positives = 33/75 (44%), Gaps = 12/75 (16%) Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDR 224 E+L+ AF +D +KDG I ++ M+++ M L Q+++ Sbjct: 10 EELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELS------------QQINM 57 Query: 225 NQDGVVTIDEFLETC 239 N G V D+F+E Sbjct: 58 NLGGHVDFDDFVELM 72 Score = 27.7 bits (60), Expect = 4.7, Method: Composition-based stats. Identities = 12/69 (17%), Positives = 23/69 (33%), Gaps = 2/69 (2%) Query: 91 KELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFED 150 +EL+ +R F + G ++ L + + G + F+D Sbjct: 10 EELREAFREFDKD-KDGYINCRDLGNCMRTMGYMPTEMELIE-LSQQINMNLGGHVDFDD 67 Query: 151 FVVGLSILL 159 FV + L Sbjct: 68 FVELMGPKL 76 Score = 26.6 bits (57), Expect = 9.8, Method: Composition-based stats. Identities = 11/57 (19%), Positives = 23/57 (40%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIM 191 F FD D +G I+ D + + +L ++N G + ++ + +M Sbjct: 16 FREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQQINMNLGGHVDFDDFVELM 72 >1TTX-A nrPDB Length = 109 Score = 45.1 bits (105), Expect = 3e-05, Method: Composition-based stats. Identities = 13/83 (15%), Positives = 28/83 (33%), Gaps = 9/83 (10%) Query: 159 LRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERF 218 L ++K F D ++ G + +EE+ ++ + + + Sbjct: 36 LSKMSANQVKDVFRFIDNDQSGYLDEEELKFFLQK---------FESGARELTESETKSL 86 Query: 219 FQKMDRNQDGVVTIDEFLETCQK 241 D + DG + +EF E Sbjct: 87 MAAADNDGDGKIGAEEFQEMVHS 109 Score = 35.8 bits (81), Expect = 0.018, Method: Composition-based stats. Identities = 20/83 (24%), Positives = 37/83 (44%), Gaps = 3/83 (3%) Query: 76 PEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAH--F 133 P+ Q +K + +++ ++R F + +G +DE+ K +F T + Sbjct: 27 PQKFFQTSGLSKMSANQVKDVFR-FIDNDQSGYLDEEELKFFLQKFESGARELTESETKS 85 Query: 134 LFNAFDADGNGAIHFEDFVVGLS 156 L A D DG+G I E+F + Sbjct: 86 LMAAADNDGDGKIGAEEFQEMVH 108 Score = 33.5 bits (75), Expect = 0.094, Method: Composition-based stats. Identities = 15/63 (23%), Positives = 24/63 (38%), Gaps = 3/63 (4%) Query: 134 LFNAFDADGNGAIHFED---FVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAI 190 +F D D +G + E+ F+ R + K D + DG I EE + Sbjct: 47 VFRFIDNDQSGYLDEEELKFFLQKFESGARELTESETKSLMAAADNDGDGKIGAEEFQEM 106 Query: 191 MKS 193 + S Sbjct: 107 VHS 109 >1A75-A nrPDB Length = 108 Score = 44.7 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 15/83 (18%), Positives = 33/83 (39%), Gaps = 9/83 (10%) Query: 159 LRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERF 218 L G + +K AF D +K G I ++E+ ++ + + F Sbjct: 35 LSGKSADDIKKAFVFIDQDKSGFIEEDELKLFLQ---------VFKAGARALTDAETKAF 85 Query: 219 FQKMDRNQDGVVTIDEFLETCQK 241 + D + DG + ++E++ + Sbjct: 86 LKAGDSDGDGAIGVEEWVALVKA 108 Score = 34.7 bits (78), Expect = 0.038, Method: Composition-based stats. Identities = 18/83 (21%), Positives = 33/83 (39%), Gaps = 3/83 (3%) Query: 114 FKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFED---FVVGLSILLRGTVHEKLKWA 170 +K +++ G + F D D +G I ++ F+ R + K Sbjct: 26 YKAFFAKCGLSGKSADDIKKAFVFIDQDKSGFIEEDELKLFLQVFKAGARALTDAETKAF 85 Query: 171 FNLYDINKDGCITKEEMLAIMKS 193 D + DG I EE +A++K+ Sbjct: 86 LKAGDSDGDGAIGVEEWVALVKA 108 >1S36-A nrPDB Length = 195 Score = 44.7 bits (104), Expect = 4e-05, Method: Composition-based stats. Identities = 14/59 (23%), Positives = 25/59 (42%) Query: 131 AHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLA 189 +F+ FD DG+G I +++ I E + F D++ G + +EM Sbjct: 115 GDAVFDIFDKDGSGTITLDEWKAYGKISGISPSQEDCEATFRHCDLDNSGDLDVDEMTR 173 Score = 38.5 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 21/113 (18%), Positives = 39/113 (34%), Gaps = 11/113 (9%) Query: 133 FLFNAFDADGNGAIHFEDFVVGLS----ILLRGTVHEK------LKWAFNLYDINKDGCI 182 +F+ D +GNG I ++ V S L T + ++ F + I Sbjct: 24 HMFDFLDINGNGKITLDEIVSKASDDICAKLEATPEQTKRHQVCVEAFFRGCGMEYGKEI 83 Query: 183 TKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEF 235 + L K + + E + F D++ G +T+DE+ Sbjct: 84 AFPQFLDGFKQLATSELKKWARNEP-TLIREWGDAVFDIFDKDGSGTITLDEW 135 Score = 29.3 bits (64), Expect = 1.8, Method: Composition-based stats. Identities = 8/30 (26%), Positives = 15/30 (50%) Query: 213 EHVERFFQKMDRNQDGVVTIDEFLETCQKD 242 + + F +D N +G +T+DE + D Sbjct: 20 KRHKHMFDFLDINGNGKITLDEIVSKASDD 49 >2M7M-A nrPDB Length = 66 Score = 44.3 bits (103), Expect = 5e-05, Method: Composition-based stats. Identities = 17/65 (26%), Positives = 28/65 (43%) Query: 130 YAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLA 189 A LF D +G+GA+ +E+ +S + L+ F D + +G I + E Sbjct: 1 MAEALFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDADGNGEIDQNEFAK 60 Query: 190 IMKSI 194 SI Sbjct: 61 FYGSI 65 Score = 38.5 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 13/69 (18%), Positives = 29/69 (42%), Gaps = 12/69 (17%) Query: 170 AFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGV 229 F D+N DG ++ EE+ A + + + ++ F+ +D + +G Sbjct: 5 LFKEIDVNGDGAVSYEEVKAFVSKKRAIKN------------EQLLQLIFKSIDADGNGE 52 Query: 230 VTIDEFLET 238 + +EF + Sbjct: 53 IDQNEFAKF 61 Score = 33.9 bits (76), Expect = 0.075, Method: Composition-based stats. Identities = 13/49 (26%), Positives = 19/49 (38%), Gaps = 1/49 (2%) Query: 105 PTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVV 153 G V + K S+ + +F + DADGNG I +F Sbjct: 13 GDGAVSYEEVKAFVSKKRAIKNEQLL-QLIFKSIDADGNGEIDQNEFAK 60 Score = 30.8 bits (68), Expect = 0.57, Method: Composition-based stats. Identities = 10/32 (31%), Positives = 15/32 (46%) Query: 214 HVERFFQKMDRNQDGVVTIDEFLETCQKDENI 245 E F+++D N DG V+ +E K I Sbjct: 1 MAEALFKEIDVNGDGAVSYEEVKAFVSKKRAI 32 >1GGW-A nrPDB Length = 140 Score = 44.3 bits (103), Expect = 5e-05, Method: Composition-based stats. Identities = 18/112 (16%), Positives = 42/112 (37%), Gaps = 18/112 (16%) Query: 135 FNAFDADGNGAIHFEDFVVGLSI----LLRGTVHEKLKWAFNLYDINKDGCITKEEMLAI 190 ++ + E F+ L+ + G E +K F ++D + G I E+ + Sbjct: 43 ITEIESTLPAEVDMEQFLQVLNRPNGFDMPGDPEEFVK-GFQVFDKDATGMIGVGELRYV 101 Query: 191 MKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKD 242 + S+ + + L + P++ DG+V +F++ + Sbjct: 102 LTSLGEKLSNEEMDELLKGVPVK-------------DGMVNYHDFVQMILAN 140 Score = 32.4 bits (72), Expect = 0.21, Method: Composition-based stats. Identities = 16/95 (16%), Positives = 33/95 (34%), Gaps = 25/95 (26%) Query: 168 KWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQD 227 K AF+L+D + G I K + ++++ + P E Sbjct: 8 KQAFSLFDRHGTGRIPKTSIGDLLRACGQNPTLAEITEIESTLPAE-------------- 53 Query: 228 GVVTIDEFLETCQK---------DENIMNSMQLFE 253 V +++FL+ + E + Q+F+ Sbjct: 54 --VDMEQFLQVLNRPNGFDMPGDPEEFVKGFQVFD 86 >5ZH6-A nrPDB Length = 107 Score = 44.3 bits (103), Expect = 5e-05, Method: Composition-based stats. Identities = 14/83 (16%), Positives = 29/83 (34%), Gaps = 9/83 (10%) Query: 159 LRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERF 218 L L F++ D ++ G I +E+ +++ + + F Sbjct: 34 LTNKSDANLAKVFDILDQDRSGFIEVDELKLFLQN---------FSATARELDETETNAF 84 Query: 219 FQKMDRNQDGVVTIDEFLETCQK 241 D + DG + +DEF + Sbjct: 85 LAAGDSDHDGKIGVDEFKAMVKA 107 Score = 36.6 bits (83), Expect = 0.012, Method: Composition-based stats. Identities = 15/63 (23%), Positives = 27/63 (42%), Gaps = 3/63 (4%) Query: 134 LFNAFDADGNGAIHFED---FVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAI 190 +F+ D D +G I ++ F+ S R + D + DG I +E A+ Sbjct: 45 VFDILDQDRSGFIEVDELKLFLQNFSATARELDETETNAFLAAGDSDHDGKIGVDEFKAM 104 Query: 191 MKS 193 +K+ Sbjct: 105 VKA 107 >1S6J-A nrPDB Length = 87 Score = 44.3 bits (103), Expect = 5e-05, Method: Composition-based stats. Identities = 13/73 (17%), Positives = 26/73 (35%), Gaps = 12/73 (16%) Query: 167 LKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQ 226 LK F + D + G IT +E+ +K + + ++ D ++ Sbjct: 25 LKELFKMIDTDNSGTITFDELKDGLK------------RVGSELMESEIKDLMDAADIDK 72 Query: 227 DGVVTIDEFLETC 239 G + EF+ Sbjct: 73 SGTIDYGEFIAAT 85 Score = 42.8 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 14/77 (18%), Positives = 31/77 (40%), Gaps = 3/77 (3%) Query: 80 DQLQAQTKFTKKELQSLYRGFK--NECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNA 137 D + +++E+ L FK + +G + D K + + + + +A Sbjct: 9 DDKHMAERLSEEEIGGLKELFKMIDTDNSGTITFDELKDGLKRVGSELMESEIKDLM-DA 67 Query: 138 FDADGNGAIHFEDFVVG 154 D D +G I + +F+ Sbjct: 68 ADIDKSGTIDYGEFIAA 84 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 16/53 (30%), Positives = 25/53 (47%) Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEE 186 LF D D +G I F++ GL + + ++K + DI+K G I E Sbjct: 28 LFKMIDTDNSGTITFDELKDGLKRVGSELMESEIKDLMDAADIDKSGTIDYGE 80 Score = 29.7 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 9/42 (21%), Positives = 20/42 (47%), Gaps = 1/42 (2%) Query: 200 RHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 +H L E+ ++ F+ +D + G +T DE + ++ Sbjct: 11 KHMAERLSEEEI-GGLKELFKMIDTDNSGTITFDELKDGLKR 51 >4D1E-A nrPDB Length = 876 Score = 44.3 bits (103), Expect = 5e-05, Method: Composition-based stats. Identities = 23/132 (17%), Positives = 51/132 (38%), Gaps = 8/132 (6%) Query: 66 ELELSTVRHQPEGLDQ---LQAQTKFTKKELQSLYRGF--KNECPTGLVDEDTFKLIYSQ 120 EL L+T+ ++ + T++++ F + GL+D + F+ Sbjct: 707 ELLLTTIARTINEVETQILTRDAKGITQEQMNEFRASFNHFDRRKNGLMDHEDFRACLIS 766 Query: 121 FFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKD 179 +A + D +G G + F+ F+ ++ T E++ +F + +K Sbjct: 767 MGYDLGEAEFA-RIMTLVDPNGQGTVTFQSFIDFMTRETADTDTAEQVIASFRILASDKP 825 Query: 180 GCITKEEMLAIM 191 I EE+ + Sbjct: 826 -YILAEELRREL 836 Score = 37.0 bits (84), Expect = 0.009, Method: Composition-based stats. Identities = 19/91 (20%), Positives = 36/91 (39%), Gaps = 15/91 (16%) Query: 155 LSILLRGTVHEKL---KWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAP 211 L+ +G E++ + +FN +D K+G + E+ A + S+ D Sbjct: 725 LTRDAKGITQEQMNEFRASFNHFDRRKNGLMDHEDFRACLISMGY------------DLG 772 Query: 212 LEHVERFFQKMDRNQDGVVTIDEFLETCQKD 242 R +D N G VT F++ ++ Sbjct: 773 EAEFARIMTLVDPNGQGTVTFQSFIDFMTRE 803 >4L9M-A nrPDB Length = 559 Score = 44.3 bits (103), Expect = 5e-05, Method: Composition-based stats. Identities = 13/71 (18%), Positives = 30/71 (42%), Gaps = 9/71 (12%) Query: 130 YAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLA 189 +F +D D +G I E+F + ++F + D +++G I+++E+ A Sbjct: 426 MVDSVFKNYDHDQDGYISQEEFEKIAASFP---------FSFCVMDKDREGLISRDEITA 476 Query: 190 IMKSIYDMMGR 200 + + Sbjct: 477 YFMRASSIYSK 487 Score = 37.4 bits (85), Expect = 0.006, Method: Composition-based stats. Identities = 9/46 (19%), Positives = 17/46 (36%) Query: 198 MGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDE 243 + P V+ F+ D +QDG ++ +EF + Sbjct: 410 VSPKPDPKTISKHVQRMVDSVFKNYDHDQDGYISQEEFEKIAASFP 455 Score = 33.9 bits (76), Expect = 0.073, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 33/81 (40%), Gaps = 21/81 (25%) Query: 171 FNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVV 230 F YD ++DG I++EE I S F MD++++G++ Sbjct: 431 FKNYDHDQDGYISQEEFEKIAASFPFS---------------------FCVMDKDREGLI 469 Query: 231 TIDEFLETCQKDENIMNSMQL 251 + DE + +I + + L Sbjct: 470 SRDEITAYFMRASSIYSKLGL 490 >4I5L-B nrPDB Length = 413 Score = 44.3 bits (103), Expect = 6e-05, Method: Composition-based stats. Identities = 31/174 (17%), Positives = 60/174 (34%), Gaps = 16/174 (9%) Query: 69 LSTVRHQPEGLDQLQAQTKFTKKELQSLYRGF--KNECPTGLVDEDTFKLIYSQFFPQGD 126 L V E D Q F+ + +Y F + L+D D ++ Sbjct: 173 LQNVALLEEEADINQLTEFFSYEHFYVIYCKFWELDTDHDLLIDADD----LARHNDHAL 228 Query: 127 ATTYAHFLFNAFDADG-----NGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGC 181 +T +F+ G G I + DFV L +++ F D++ DG Sbjct: 229 STKMIDRIFSGAVTRGRKVQKEGKISYADFVWFLISEEDKKTPTSIEYWFRCMDLDGDGA 288 Query: 182 ITKEEMLAIMKSIYDMMGRHTYPILREDAPLEH-VERFFQKMDRNQDGVVTIDE 234 ++ E+ Y+ R + E P + + + + +G +T+ + Sbjct: 289 LSMFELEYF----YEEQCRRLDSMAIEALPFQDCLCQMLDLVKPRTEGKITLQD 338 >3MSE-B nrPDB Length = 180 Score = 44.3 bits (103), Expect = 6e-05, Method: Composition-based stats. Identities = 22/149 (14%), Positives = 50/149 (33%), Gaps = 15/149 (10%) Query: 93 LQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFV 152 + L+ G + + + + + + A D + G I + +F+ Sbjct: 41 INELFYKLDTNH-NGSLSHREIYTVLASVGIKKWD---INRILQALDINDRGNITYTEFM 96 Query: 153 VGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPL 212 G + LK AFN D ++DG I+K ++++++ L + Sbjct: 97 AGCYRW-KNIESTFLKAAFNKIDKDEDGYISKSDIVSLVHDKVLDNNDIDNFFLSVHSIK 155 Query: 213 EHV--ERFFQKMDRNQDGVVTIDEFLETC 239 + + E ++ EF + Sbjct: 156 KGIPREHII--------NKISFQEFKDYM 176 Score = 37.4 bits (85), Expect = 0.007, Method: Composition-based stats. Identities = 17/83 (20%), Positives = 33/83 (39%), Gaps = 14/83 (16%) Query: 167 LKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQ 226 + F D N +G ++ E+ ++ S+ + R Q +D N Sbjct: 41 INELFYKLDTNHNGSLSHREIYTVLASVG--------------IKKWDINRILQALDIND 86 Query: 227 DGVVTIDEFLETCQKDENIMNSM 249 G +T EF+ C + +NI ++ Sbjct: 87 RGNITYTEFMAGCYRWKNIESTF 109 Score = 36.2 bits (82), Expect = 0.013, Method: Composition-based stats. Identities = 22/112 (19%), Positives = 41/112 (36%), Gaps = 15/112 (13%) Query: 129 TYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEML 188 Y + LF D + NG++ + L+ + G + DIN G IT E Sbjct: 39 KYINELFYKLDTNHNGSLSHREIYTVLASV--GIKKWDINRILQALDINDRGNITYTE-- 94 Query: 189 AIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQ 240 M Y + ++ F K+D+++DG ++ + + Sbjct: 95 -FMAGCYRWKNIEST----------FLKAAFNKIDKDEDGYISKSDIVSLVH 135 >4MSP-A nrPDB Length = 200 Score = 44.3 bits (103), Expect = 6e-05, Method: Composition-based stats. Identities = 19/70 (27%), Positives = 35/70 (50%), Gaps = 4/70 (5%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRN 225 + +F D+N D ++K+E+ A +K ++ G ++ E VE F K D + Sbjct: 128 RSHESFQEMDLNDDWKLSKDEVKAYLKKEFEKHG----AVVNESHHDALVEDIFDKEDED 183 Query: 226 QDGVVTIDEF 235 +DG ++ EF Sbjct: 184 KDGFISAREF 193 >1IJ5-A nrPDB Length = 323 Score = 43.9 bits (102), Expect = 6e-05, Method: Composition-based stats. Identities = 22/135 (16%), Positives = 50/135 (37%), Gaps = 19/135 (14%) Query: 102 NECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRG 161 + G + F+ + + + LF D D + + F ++V LL Sbjct: 198 DTNSNGTLSRKEFREHFVRLGFDKKSVQ--DALFRYADEDESDDVGFSEYVHLGLCLLV- 254 Query: 162 TVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQK 221 L+ + D +K G ++KEE+ +++ + ++ + E F Sbjct: 255 -----LRILYAFADFDKSGQLSKEEVQKVLEDAHIP-----------ESARKKFEHQFSV 298 Query: 222 MDRNQDGVVTIDEFL 236 +D + ++ EF+ Sbjct: 299 VDVDDSKSLSYQEFV 313 Score = 33.5 bits (75), Expect = 0.089, Method: Composition-based stats. Identities = 8/57 (14%), Positives = 24/57 (42%) Query: 99 GFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGL 155 F + +G + ++ + + A F+ D D + ++ +++FV+ + Sbjct: 260 AFADFDKSGQLSKEEVQKVLEDAHIPESARKKFEHQFSVVDVDDSKSLSYQEFVMLV 316 Score = 28.5 bits (62), Expect = 2.6, Method: Composition-based stats. Identities = 21/112 (18%), Positives = 42/112 (37%), Gaps = 18/112 (16%) Query: 126 DATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKE 185 + T LF + G+G F+D L+ LK F + + + G ++ Sbjct: 119 EDTNILRQLFLSSAVSGSGKFSFQDLKQVLAKYADTIPEGPLKKLFVMVENDTKGRMSYI 178 Query: 186 EMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLE 237 ++A+ + ++ F+K+D N +G ++ EF E Sbjct: 179 TLVAVANDLAALVAD------------------FRKIDTNSNGTLSRKEFRE 212 Score = 27.0 bits (58), Expect = 8.4, Method: Composition-based stats. Identities = 23/172 (13%), Positives = 56/172 (32%), Gaps = 26/172 (15%) Query: 88 FTKKELQSLYRGFKNE--CPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGA 145 ++++ L + F + +G K + +++ LF + D G Sbjct: 116 LSEEDTNILRQLFLSSAVSGSGKFSFQDLKQVLAKYADTIPEGPLK-KLFVMVENDTKGR 174 Query: 146 IHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIM-------KSIYDMM 198 + + V + L F D N +G ++++E KS+ D + Sbjct: 175 MSYITLVAVANDLAALVAD------FRKIDTNSNGTLSRKEFREHFVRLGFDKKSVQDAL 228 Query: 199 GRHTYPILREDAPLEH----------VERFFQKMDRNQDGVVTIDEFLETCQ 240 R+ +D + + D ++ G ++ +E + + Sbjct: 229 FRYADEDESDDVGFSEYVHLGLCLLVLRILYAFADFDKSGQLSKEEVQKVLE 280 >4OKH-A nrPDB Length = 189 Score = 43.9 bits (102), Expect = 7e-05, Method: Composition-based stats. Identities = 29/176 (16%), Positives = 60/176 (34%), Gaps = 33/176 (18%) Query: 91 KELQSLYRGFKNECPTGL-VDEDTFKLIYSQFFPQGDATTY-------AHFLFNAFDADG 142 +E Q FK + + D K + + + + D DG Sbjct: 9 EEQQQFRNIFKQIAGDDMEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDG 68 Query: 143 NGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHT 202 +G ++ ++F + + +K+ F YD ++ G I EM + + Sbjct: 69 SGKLNLQEF---HHLWNKIKAWQKI---FKHYDTDQSGTINSYEMRNAVNDAGFHLNNQL 122 Query: 203 YPILREDAPLEHVE-----------------RFFQKMDRNQDGVVTID--EFLETC 239 Y I+ +H+ R F D++ DG++ ++ E+L+ Sbjct: 123 YDIITMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLT 178 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 18/107 (16%), Positives = 40/107 (37%), Gaps = 10/107 (9%) Query: 93 LQSLYRGFK--NECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFED 150 +++ + FK + +G ++ + + + Y D N I F+ Sbjct: 84 IKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMN--IDFDS 141 Query: 151 FVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDM 197 F+ L E + AF+ +D + DG I + + ++Y + Sbjct: 142 FICCFVRL------EGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYAL 182 Score = 31.6 bits (70), Expect = 0.33, Method: Composition-based stats. Identities = 13/90 (14%), Positives = 32/90 (35%), Gaps = 5/90 (5%) Query: 164 HEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMD 223 ++ + F + D I +E+ ++ ++ + +H LE MD Sbjct: 11 QQQFRNIFKQIAGD-DMEICADELKKVLNTV---VNKHKDLKTHG-FTLESCRSMIALMD 65 Query: 224 RNQDGVVTIDEFLETCQKDENIMNSMQLFE 253 + G + + EF K + + ++ Sbjct: 66 TDGSGKLNLQEFHHLWNKIKAWQKIFKHYD 95 >5H53-B nrPDB Length = 146 Score = 43.9 bits (102), Expect = 7e-05, Method: Composition-based stats. Identities = 18/120 (15%), Positives = 44/120 (36%), Gaps = 7/120 (5%) Query: 90 KKELQSLYRGFK--NECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIH 147 + ++Q F ++ G++D++ + ++ + +G I+ Sbjct: 1 QTQIQEFKEAFTVIDQNRDGIIDKEDLRDTFAAMGRLNVKNEELDAMMKE----ASGPIN 56 Query: 148 FEDFVVGLSILLRGTVHEKLKW-AFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPIL 206 F F+ L+G E + AF + D G I K+ + ++ + D + + Sbjct: 57 FTVFLTMFGEKLKGADPEDVITGAFKVLDPEGKGTIKKQFLEELLITQCDRFSQEEIKNM 116 Score = 36.2 bits (82), Expect = 0.014, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 30/74 (40%), Gaps = 15/74 (20%) Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDR 224 ++ K AF + D N+DG I KE++ ++ + ++ E ++ ++ Sbjct: 5 QEFKEAFTVIDQNRDGIIDKEDLRDTFAAMGRLNVKN-----------EELDAMMKEA-- 51 Query: 225 NQDGVVTIDEFLET 238 G + FL Sbjct: 52 --SGPINFTVFLTM 63 >4PAL-A nrPDB Length = 108 Score = 43.5 bits (101), Expect = 8e-05, Method: Composition-based stats. Identities = 16/93 (17%), Positives = 39/93 (41%), Gaps = 11/93 (11%) Query: 149 EDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILRE 208 ++F + + + + +K AF + D +K G I ++E+ +++ + Sbjct: 27 KEFFAKVGLASKSL--DDVKKAFYVIDQDKSGFIEEDELKLFLQN---------FSPSAR 75 Query: 209 DAPLEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 + F D++ DG++ +DEF + Sbjct: 76 ALTDAETKAFLADGDKDGDGMIGVDEFAAMIKA 108 Score = 33.1 bits (74), Expect = 0.13, Method: Composition-based stats. Identities = 20/79 (25%), Positives = 33/79 (41%), Gaps = 4/79 (5%) Query: 81 QLQAQTKFTKKELQSLYRGF--KNECPTGLVDEDTFKLIYSQFFPQGDATTYAH--FLFN 136 + A+ K L + + F ++ +G ++ED KL F P A T A Sbjct: 28 EFFAKVGLASKSLDDVKKAFYVIDQDKSGFIEEDELKLFLQNFSPSARALTDAETKAFLA 87 Query: 137 AFDADGNGAIHFEDFVVGL 155 D DG+G I ++F + Sbjct: 88 DGDKDGDGMIGVDEFAAMI 106 >1NYA-A nrPDB Length = 176 Score = 43.5 bits (101), Expect = 8e-05, Method: Composition-based stats. Identities = 19/95 (20%), Positives = 39/95 (41%), Gaps = 9/95 (9%) Query: 105 PTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAF-------DADGNGAIHFEDFVVGLSI 157 G + E+ F + + ++ L D + +G I+ ++F L+ Sbjct: 71 SDGSLTEEQFIRVTENLIFEQGEASFNRVLGPVVKGIVGMCDKNADGQINADEFAAWLTA 130 Query: 158 LLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMK 192 L G + AFN D N +G ++ +E+L ++ Sbjct: 131 L--GMSKAEAAEAFNQVDTNGNGELSLDELLTAVR 163 Score = 39.7 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 29/116 (25%), Positives = 50/116 (43%), Gaps = 19/116 (16%) Query: 135 FNAFDADGNGAIHFEDF------VVGLSILLRGTVH-EKLKWAFN-LYD-------INKD 179 F+ +D DGNGA+ DF + G + LK AF L+D + D Sbjct: 13 FDRWDFDGNGALERADFEKEAQHIAEAFGKDAGAAEVQTLKNAFGGLFDYLAKEAGVGSD 72 Query: 180 GCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEF 235 G +T+E+ + + +++ G ++ + V+ D+N DG + DEF Sbjct: 73 GSLTEEQFIRVTENLIFEQGEASFNRVLGPV----VKGIVGMCDKNADGQINADEF 124 Score = 36.2 bits (82), Expect = 0.016, Method: Composition-based stats. Identities = 13/69 (18%), Positives = 26/69 (37%), Gaps = 3/69 (4%) Query: 99 GFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSIL 158 G ++ G ++ D F + A FN D +GNG + ++ + + Sbjct: 109 GMCDKNADGQINADEFAAWLTALGMSKAEAAEA---FNQVDTNGNGELSLDELLTAVRDF 165 Query: 159 LRGTVHEKL 167 G + +L Sbjct: 166 HFGRLDVEL 174 Score = 34.3 bits (77), Expect = 0.049, Method: Composition-based stats. Identities = 14/66 (21%), Positives = 25/66 (37%), Gaps = 14/66 (21%) Query: 175 DINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDE 234 D N DG I +E A + ++ F ++D N +G +++DE Sbjct: 112 DKNADGQINADEFAAWLTALG--------------MSKAEAAEAFNQVDTNGNGELSLDE 157 Query: 235 FLETCQ 240 L + Sbjct: 158 LLTAVR 163 Score = 33.9 bits (76), Expect = 0.076, Method: Composition-based stats. Identities = 11/80 (13%), Positives = 32/80 (40%), Gaps = 3/80 (3%) Query: 164 HEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEH---VERFFQ 220 ++LK F+ +D + +G + + + + I + G+ + + + Sbjct: 6 SDRLKKRFDRWDFDGNGALERADFEKEAQHIAEAFGKDAGAAEVQTLKNAFGGLFDYLAK 65 Query: 221 KMDRNQDGVVTIDEFLETCQ 240 + DG +T ++F+ + Sbjct: 66 EAGVGSDGSLTEEQFIRVTE 85 >1SL8-A nrPDB Length = 191 Score = 43.5 bits (101), Expect = 8e-05, Method: Composition-based stats. Identities = 16/82 (19%), Positives = 29/82 (35%), Gaps = 2/82 (2%) Query: 108 LVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKL 167 + + K + LF+ D D NGAI +++ E Sbjct: 90 RLASEELKRYSKNQITLIR--LWGDALFDIIDKDQNGAISLDEWKAYTKSAGIIQSSEDC 147 Query: 168 KWAFNLYDINKDGCITKEEMLA 189 + F + DI++ G + +EM Sbjct: 148 EETFRVCDIDESGQLDVDEMTR 169 Score = 35.8 bits (81), Expect = 0.017, Method: Composition-based stats. Identities = 19/120 (15%), Positives = 44/120 (36%), Gaps = 13/120 (10%) Query: 133 FLFNAFDADGNGAIHFEDFVVGLSILL---------RGTVHEKLKWAFNLYDINKDGCIT 183 +FN D + NG I ++ V S ++ + H+ AF + Sbjct: 20 HMFNFLDVNHNGRISLDEMVYKASDIVINNLGATPEQAKRHKDAVEAF--FGGAGMKYGV 77 Query: 184 KEEMLAIMKSIYDMMGRHTYPILREDAPLEHV--ERFFQKMDRNQDGVVTIDEFLETCQK 241 + E ++ + + L + + F +D++Q+G +++DE+ + Sbjct: 78 ETEWPEYIEGWKRLASEELKRYSKNQITLIRLWGDALFDIIDKDQNGAISLDEWKAYTKS 137 Score = 33.5 bits (75), Expect = 0.089, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 28/65 (43%), Gaps = 12/65 (18%) Query: 170 AFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGV 229 F++ D +++G I+ +E A KS + E E F+ D ++ G Sbjct: 114 LFDIIDKDQNGAISLDEWKAYTKSAGIIQSS------------EDCEETFRVCDIDESGQ 161 Query: 230 VTIDE 234 + +DE Sbjct: 162 LDVDE 166 >4MEW-A nrPDB Length = 356 Score = 43.5 bits (101), Expect = 9e-05, Method: Composition-based stats. Identities = 31/174 (17%), Positives = 60/174 (34%), Gaps = 16/174 (9%) Query: 69 LSTVRHQPEGLDQLQAQTKFTKKELQSLYRGF--KNECPTGLVDEDTFKLIYSQFFPQGD 126 L V E D Q F+ + +Y F + L+D D ++ Sbjct: 165 LQNVALLEEEADINQLTEFFSYEHFYVIYCKFWELDTDHDLLIDADD----LARHNDHAL 220 Query: 127 ATTYAHFLFNAFDADG-----NGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGC 181 +T +F+ G G I + DFV L +++ F D++ DG Sbjct: 221 STKMIDRIFSGAVTRGRKVQKEGKISYADFVWFLISEEDKKTPTSIEYWFRCMDLDGDGA 280 Query: 182 ITKEEMLAIMKSIYDMMGRHTYPILREDAPLEH-VERFFQKMDRNQDGVVTIDE 234 ++ E+ Y+ R + E P + + + + +G +T+ + Sbjct: 281 LSMFELEYF----YEEQCRRLDSMAIEALPFQDCLCQMLDLVKPRTEGKITLQD 330 >6AGH-A nrPDB Length = 339 Score = 43.5 bits (101), Expect = 9e-05, Method: Composition-based stats. Identities = 20/122 (16%), Positives = 39/122 (31%), Gaps = 9/122 (7%) Query: 139 DADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYD-- 196 D G I + +++ L+IL + H AF + D + + I K E + K I Sbjct: 92 DLGDKGLISYTEYLFLLTILTK--PHSGFHVAFKMLDTDGNEMIEKREFFKLQKIISKQD 149 Query: 197 -----MMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQL 251 Y P + + + + EF + + + M+ Sbjct: 150 DLMTVKTNETGYQEAIVKEPEINTTLQMRFFGKRGQRKLHYKEFRRFMENLQTEIQEMEF 209 Query: 252 FE 253 + Sbjct: 210 LQ 211 Score = 37.7 bits (86), Expect = 0.004, Method: Composition-based stats. Identities = 21/110 (19%), Positives = 45/110 (40%), Gaps = 8/110 (7%) Query: 87 KFTKKELQSLY-RGFKNECPTG-LVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNG 144 FT E + +Y + + + G + D FK F + A +F+ Sbjct: 230 FFTNTENKDIYWKNVREKLSAGESISLDEFKSFCH-FTTHLEDFAIAMQMFSLAHRP--- 285 Query: 145 AIHFEDFVVGLSI-LLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS 193 + +F + + + + L F ++D++ D C++ EE L ++K+ Sbjct: 286 -VRLAEFKRAVKVATGQELSNNILDTVFKIFDLDGDECLSHEEFLGVLKN 334 Score = 29.3 bits (64), Expect = 1.7, Method: Composition-based stats. Identities = 11/47 (23%), Positives = 18/47 (38%) Query: 113 TFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILL 159 FK Q + +F FD DG+ + E+F+ L + Sbjct: 290 EFKRAVKVATGQELSNNILDTVFKIFDLDGDECLSHEEFLGVLKNRM 336 >5CPV-A nrPDB Length = 109 Score = 43.5 bits (101), Expect = 9e-05, Method: Composition-based stats. Identities = 16/83 (19%), Positives = 33/83 (39%), Gaps = 9/83 (10%) Query: 159 LRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERF 218 L + +K AF + D +K G I ++E+ +++ + + F Sbjct: 36 LTSKSADDVKKAFAIIDQDKSGFIEEDELKLFLQN---------FKADARALTDGETKTF 86 Query: 219 FQKMDRNQDGVVTIDEFLETCQK 241 + D + DG + +DEF + Sbjct: 87 LKAGDSDGDGKIGVDEFTALVKA 109 Score = 35.4 bits (80), Expect = 0.026, Method: Composition-based stats. Identities = 16/82 (19%), Positives = 30/82 (36%), Gaps = 3/82 (3%) Query: 115 KLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFED---FVVGLSILLRGTVHEKLKWAF 171 K +++ + F D D +G I ++ F+ R + K Sbjct: 28 KAFFAKVGLTSKSADDVKKAFAIIDQDKSGFIEEDELKLFLQNFKADARALTDGETKTFL 87 Query: 172 NLYDINKDGCITKEEMLAIMKS 193 D + DG I +E A++K+ Sbjct: 88 KAGDSDGDGKIGVDEFTALVKA 109 >1G33-A nrPDB Length = 73 Score = 43.1 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 15/81 (18%), Positives = 34/81 (41%), Gaps = 9/81 (11%) Query: 162 TVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQK 221 + +K F++ D +K G I ++E+ +I+K + D + + Sbjct: 2 KSADDVKKVFHILDKDKSGFIEEDELGSILKG---------FSSDARDLSAKETKTLMAA 52 Query: 222 MDRNQDGVVTIDEFLETCQKD 242 D++ DG + ++EF + Sbjct: 53 GDKDGDGKIGVEEFSTLVAES 73 Score = 32.0 bits (71), Expect = 0.23, Method: Composition-based stats. Identities = 14/64 (21%), Positives = 22/64 (34%), Gaps = 3/64 (4%) Query: 131 AHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLY---DINKDGCITKEEM 187 +F+ D D +G I ++ L K L D + DG I EE Sbjct: 7 VKKVFHILDKDKSGFIEEDELGSILKGFSSDARDLSAKETKTLMAAGDKDGDGKIGVEEF 66 Query: 188 LAIM 191 ++ Sbjct: 67 STLV 70 Score = 29.3 bits (64), Expect = 1.6, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 24/58 (41%), Gaps = 2/58 (3%) Query: 101 KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHF--LFNAFDADGNGAIHFEDFVVGLS 156 ++ +G ++ED I F + L A D DG+G I E+F ++ Sbjct: 14 LDKDKSGFIEEDELGSILKGFSSDARDLSAKETKTLMAAGDKDGDGKIGVEEFSTLVA 71 >1F4Q-A nrPDB Length = 165 Score = 43.1 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 22/154 (14%), Positives = 50/154 (32%), Gaps = 24/154 (15%) Query: 106 TGLVDEDTFKLIYSQFFPQGDATTYA----HFLFNAFDADGNGAIHFEDFVVGLSILLRG 161 G VD + + +Q G + ++ + D D G + F F + L Sbjct: 13 DGEVDAEELQRCLTQSGINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAFKELWAAL--- 69 Query: 162 TVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQK 221 K F D + G + E+ + + + T ++ Sbjct: 70 ---NAWKENFMTVDQDGSGTVEHHELRQAIGLMGYRLSPQTLTT------------IVKR 114 Query: 222 MDRNQDGVVTIDEFLETCQKDENIMNSMQLFENV 255 +N G + D+++ C K + + + +++ Sbjct: 115 YSKN--GRIFFDDYVACCVKLRALTDFFKKRDHL 146 >5B7X-A nrPDB Length = 156 Score = 43.1 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 23/141 (16%), Positives = 46/141 (32%), Gaps = 14/141 (9%) Query: 100 FKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGA-IHFEDFVVGLSIL 158 F + G +D + ++ F +G I + ++ Sbjct: 21 FYDRDYDGKIDVKQLGTLIRSLGCAPTEDEVNSYI-KEFAIEGETFQIEQFELIMEREQS 79 Query: 159 LRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERF 218 T KL+ AF ++D +KDG I ++ H + + E VE+ Sbjct: 80 KPDTREIKLRKAFEVFDQDKDGKIKASDLA------------HNLTTVGDKMTKEEVEKV 127 Query: 219 FQKMDRNQDGVVTIDEFLETC 239 F + + + + FL+ Sbjct: 128 FSILGITMESDIDLATFLKLV 148 Score = 33.5 bits (75), Expect = 0.092, Method: Composition-based stats. Identities = 16/91 (17%), Positives = 36/91 (39%), Gaps = 25/91 (27%) Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIY-----DMMGRHTYPILRE----------- 208 +K++ FN YD + DG I +++ +++S+ D + + E Sbjct: 13 QKIRDCFNFYDRDYDGKIDVKQLGTLIRSLGCAPTEDEVNSYIKEFAIEGETFQIEQFEL 72 Query: 209 ---------DAPLEHVERFFQKMDRNQDGVV 230 D + + F+ D+++DG + Sbjct: 73 IMEREQSKPDTREIKLRKAFEVFDQDKDGKI 103 >5Z1Q-A nrPDB Length = 95 Score = 43.1 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 20/81 (24%), Positives = 34/81 (41%), Gaps = 12/81 (14%) Query: 159 LRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERF 218 L +++K AF+L+D NK G I E+ M++ L D + Sbjct: 21 LSEEQKQEIKEAFDLFDTNKTGSIDYHELKVAMRA------------LGFDVKKPEILEL 68 Query: 219 FQKMDRNQDGVVTIDEFLETC 239 + DR +G + D+FL+ Sbjct: 69 MNEYDREGNGYIGFDDFLDIM 89 Score = 40.1 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 15/57 (26%), Positives = 26/57 (45%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIM 191 F+ FD + G+I + + V + L ++ N YD +G I ++ L IM Sbjct: 33 FDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILELMNEYDREGNGYIGFDDFLDIM 89 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 15/82 (18%), Positives = 36/82 (43%), Gaps = 3/82 (3%) Query: 81 QLQAQTKFTKKELQSLYRGFK--NECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAF 138 + + + + ++++ Q + F + TG +D K+ + N + Sbjct: 14 KKRVRQELSEEQKQEIKEAFDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILELM-NEY 72 Query: 139 DADGNGAIHFEDFVVGLSILLR 160 D +GNG I F+DF+ ++ ++ Sbjct: 73 DREGNGYIGFDDFLDIMTEKIK 94 Score = 28.9 bits (63), Expect = 2.3, Method: Composition-based stats. Identities = 8/54 (14%), Positives = 18/54 (33%), Gaps = 6/54 (11%) Query: 206 LREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQ------KDENIMNSMQLFE 253 + + ++ F D N+ G + E + K I+ M ++ Sbjct: 20 ELSEEQKQEIKEAFDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILELMNEYD 73 >2NLN-A nrPDB Length = 108 Score = 43.1 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 13/83 (15%), Positives = 27/83 (32%), Gaps = 9/83 (10%) Query: 159 LRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERF 218 L ++K F D ++ G + +E+ ++ + + + Sbjct: 35 LSKMSASQVKDIFRFIDNDQSGYLDGDELKYFLQK---------FQSDARELTESETKSL 85 Query: 219 FQKMDRNQDGVVTIDEFLETCQK 241 D + DG + DEF E Sbjct: 86 MDAADNDGDGKIGADEFQEMVHS 108 Score = 37.0 bits (84), Expect = 0.007, Method: Composition-based stats. Identities = 19/83 (22%), Positives = 37/83 (44%), Gaps = 3/83 (3%) Query: 76 PEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAH--F 133 P+ Q +K + +++ ++R F + +G +D D K +F T + Sbjct: 26 PQKFFQTSGLSKMSASQVKDIFR-FIDNDQSGYLDGDELKYFLQKFQSDARELTESETKS 84 Query: 134 LFNAFDADGNGAIHFEDFVVGLS 156 L +A D DG+G I ++F + Sbjct: 85 LMDAADNDGDGKIGADEFQEMVH 107 Score = 32.4 bits (72), Expect = 0.23, Method: Composition-based stats. Identities = 13/63 (20%), Positives = 25/63 (39%), Gaps = 3/63 (4%) Query: 134 LFNAFDADGNGAIHFED---FVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAI 190 +F D D +G + ++ F+ R + K + D + DG I +E + Sbjct: 46 IFRFIDNDQSGYLDGDELKYFLQKFQSDARELTESETKSLMDAADNDGDGKIGADEFQEM 105 Query: 191 MKS 193 + S Sbjct: 106 VHS 108 >1B7T-Y nrPDB Length = 156 Score = 43.1 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 28/131 (21%), Positives = 57/131 (43%), Gaps = 8/131 (6%) Query: 86 TKFTKKELQSLYRGF--KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGN 143 TK +K++Q + F + G V ++ K I Q D L + Sbjct: 10 TKLPQKQIQEMKEAFSMIDVDRDGFVSKEDIKAISEQLGRAPDDKELTAML-----KEAP 64 Query: 144 GAIHFEDFVVGLSILLRGTVHEK-LKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHT 202 G ++F F+ S L GT E+ ++ AF ++D + + E + +++++ D + Sbjct: 65 GPLNFTMFLSIFSDKLSGTDSEETIRNAFAMFDEQETKKLNIEYIKDLLENMGDNFNKDE 124 Query: 203 YPILREDAPLE 213 + ++AP+E Sbjct: 125 MRMTFKEAPVE 135 Score = 32.4 bits (72), Expect = 0.19, Method: Composition-based stats. Identities = 18/89 (20%), Positives = 41/89 (46%), Gaps = 9/89 (10%) Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDR 224 +++K AF++ D+++DG ++KE++ AI + + + ++AP F + Sbjct: 18 QEMKEAFSMIDVDRDGFVSKEDIKAISEQLGRAPDDKELTAMLKEAPGPLNFTMFLSI-- 75 Query: 225 NQDGVVTIDEFLETCQKDENIMNSMQLFE 253 + L +E I N+ +F+ Sbjct: 76 -------FSDKLSGTDSEETIRNAFAMFD 97 >2SAS-A nrPDB Length = 185 Score = 43.1 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 26/130 (20%), Positives = 50/130 (38%), Gaps = 19/130 (14%) Query: 127 ATTYAHFLFNAF-DADGNGAIHFEDFVVGLSIL---------------LRGTVHEKLKWA 170 F F+ F D + +G+I DF ++ ++ ++ ++ + Sbjct: 6 QKQKIKFTFDFFLDMNHDGSIQDNDFEDMMTRYKEVNKGSLSDADYKSMQASLEDEWRDL 65 Query: 171 FNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVV 230 DINKD ++ EE LA+ + + F+ MD + DG+V Sbjct: 66 KGRADINKDDVVSWEEYLAMWEKTIATCKSVADLPA---WCQNRIPFLFKGMDVSGDGIV 122 Query: 231 TIDEFLETCQ 240 ++EF C+ Sbjct: 123 DLEEFQNYCK 132 Score = 39.3 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 20/88 (22%), Positives = 41/88 (46%), Gaps = 6/88 (6%) Query: 159 LRGTVHEKLKWAFNLY-DINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVER 217 L +K+K+ F+ + D+N DG I + +M + Y + + + + +E Sbjct: 2 LNDFQKQKIKFTFDFFLDMNHDGSIQDNDFEDMM-TRYKEVNKGSLSDADYKSMQASLED 60 Query: 218 FFQK----MDRNQDGVVTIDEFLETCQK 241 ++ D N+D VV+ +E+L +K Sbjct: 61 EWRDLKGRADINKDDVVSWEEYLAMWEK 88 Score = 28.5 bits (62), Expect = 2.8, Method: Composition-based stats. Identities = 16/129 (12%), Positives = 47/129 (36%), Gaps = 23/129 (17%) Query: 88 FTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATT-------YAHFLFNAF-- 138 F K++++ + F + G + ++ F+ + +++ + L + + Sbjct: 5 FQKQKIKFTFDFFLDMNHDGSIQDNDFEDMMTRYKEVNKGSLSDADYKSMQASLEDEWRD 64 Query: 139 -----DADGNGAIHFEDFVVGLSIL---------LRGTVHEKLKWAFNLYDINKDGCITK 184 D + + + +E+++ L ++ + F D++ DG + Sbjct: 65 LKGRADINKDDVVSWEEYLAMWEKTIATCKSVADLPAWCQNRIPFLFKGMDVSGDGIVDL 124 Query: 185 EEMLAIMKS 193 EE K+ Sbjct: 125 EEFQNYCKN 133 >1UHK-A nrPDB Length = 191 Score = 42.8 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 15/59 (25%), Positives = 25/59 (42%) Query: 131 AHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLA 189 LF+ D D NGAI +++ E + F + DI++ G + +EM Sbjct: 111 GDALFDIVDKDQNGAITLDEWKAYTKAAGIIQSSEDCEETFRVCDIDESGQLDVDEMTR 169 Score = 35.4 bits (80), Expect = 0.023, Method: Composition-based stats. Identities = 20/120 (16%), Positives = 46/120 (38%), Gaps = 13/120 (10%) Query: 133 FLFNAFDADGNGAIHFEDFVVGLSILL---------RGTVHEKLKWAFNLYDINKDGCIT 183 +FN D + NG I ++ V S ++ + H+ AF + Sbjct: 20 HMFNFLDVNHNGKISLDEMVYKASDIVINNLGATPEQAKRHKDAVEAF--FGGAGMKYGV 77 Query: 184 KEEMLAIMKSIYDMMGRHTYPILREDAPLEHV--ERFFQKMDRNQDGVVTIDEFLETCQK 241 + + A ++ + + + L + + F +D++Q+G +T+DE+ + Sbjct: 78 ETDWPAYIEGWKKLATDELEKYAKNEPTLIRIWGDALFDIVDKDQNGAITLDEWKAYTKA 137 Score = 34.3 bits (77), Expect = 0.057, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 28/65 (43%), Gaps = 12/65 (18%) Query: 170 AFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGV 229 F++ D +++G IT +E A K+ + E E F+ D ++ G Sbjct: 114 LFDIVDKDQNGAITLDEWKAYTKAAGIIQSS------------EDCEETFRVCDIDESGQ 161 Query: 230 VTIDE 234 + +DE Sbjct: 162 LDVDE 166 Score = 27.0 bits (58), Expect = 9.6, Method: Composition-based stats. Identities = 6/21 (28%), Positives = 13/21 (61%) Query: 216 ERFFQKMDRNQDGVVTIDEFL 236 + F +D N +G +++DE + Sbjct: 19 KHMFNFLDVNHNGKISLDEMV 39 >2JOJ-A nrPDB Length = 77 Score = 42.4 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 20/81 (24%), Positives = 34/81 (41%), Gaps = 12/81 (14%) Query: 159 LRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERF 218 L +++K AF+L+D NK G I E+ M++ L D + Sbjct: 1 LSEEQKQEIKEAFDLFDTNKTGSIDYHELKVAMRA------------LGFDVKKPEILEL 48 Query: 219 FQKMDRNQDGVVTIDEFLETC 239 + DR +G + D+FL+ Sbjct: 49 MNEYDREGNGYIGFDDFLDIM 69 Score = 39.3 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 15/57 (26%), Positives = 26/57 (45%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIM 191 F+ FD + G+I + + V + L ++ N YD +G I ++ L IM Sbjct: 13 FDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILELMNEYDREGNGYIGFDDFLDIM 69 Score = 38.1 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 16/71 (22%), Positives = 31/71 (43%), Gaps = 2/71 (2%) Query: 90 KKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFE 149 K+E++ + F TG +D K+ + N +D +GNG I F+ Sbjct: 6 KQEIKEAFDLFDTN-KTGSIDYHELKVAMRALGFDVKKPEILELM-NEYDREGNGYIGFD 63 Query: 150 DFVVGLSILLR 160 DF+ ++ ++ Sbjct: 64 DFLDIMTEKIK 74 >3JAX-C nrPDB Length = 151 Score = 42.4 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 19/162 (11%), Positives = 45/162 (27%), Gaps = 27/162 (16%) Query: 88 FTKKELQSLYRGFK--NECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNG- 144 F++++ F+ + G + + + + Sbjct: 4 FSEEQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALG----QNPTNAEVMKVLGNPKSDE 59 Query: 145 ----AIHFEDFVVGLSILLRGTVH---EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDM 197 + FE F+ + + + E ++D +G + E+ Sbjct: 60 MNLKTLKFEQFLPMMQTIAKNKDQGCFEDYVEGLRVFDKEGNGTVMGAEI---------- 109 Query: 198 MGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETC 239 RH L E E VE+ + +G + +E + Sbjct: 110 --RHVLVTLGEKMTEEEVEQLVA-GHEDSNGCINYEELVRMV 148 Score = 33.5 bits (75), Expect = 0.099, Method: Composition-based stats. Identities = 14/76 (18%), Positives = 26/76 (34%), Gaps = 12/76 (15%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYD-MMGRHTYPILREDAPLEHVERFFQKMDR 224 + K AF L+D DG I + +M+++ +L E + + Sbjct: 11 EFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVMKVLGNPKSDEMNLKTLK---- 66 Query: 225 NQDGVVTIDEFLETCQ 240 ++FL Q Sbjct: 67 -------FEQFLPMMQ 75 >5VE9-A nrPDB Length = 91 Score = 42.0 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 21/93 (22%), Positives = 35/93 (37%), Gaps = 14/93 (15%) Query: 150 DFVVGLSILLRGTVHEKLKW--AFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILR 207 DF V +R H+K + F D ++DG IT++E + + + + Sbjct: 10 DFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTA-- 67 Query: 208 EDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQ 240 V F DR+ DG + EF+ Sbjct: 68 -------VADIF---DRDGDGYIDYYEFVAALH 90 Score = 40.8 bits (94), Expect = 6e-04, Method: Composition-based stats. Identities = 17/68 (25%), Positives = 27/68 (39%), Gaps = 4/68 (5%) Query: 90 KKELQSLYRGFKNECPTGLVDEDTFKL-IYSQFFPQGDATTYAHFLFNAFDADGNGAIHF 148 K + +R + G + F I + FP A + + FD DG+G I + Sbjct: 26 KSRVMDFFRRIDKD-QDGKITRQEFIDGILASKFPTTKLEMTA--VADIFDRDGDGYIDY 82 Query: 149 EDFVVGLS 156 +FV L Sbjct: 83 YEFVAALH 90 Score = 32.7 bits (73), Expect = 0.14, Method: Composition-based stats. Identities = 10/30 (33%), Positives = 19/30 (63%) Query: 214 HVERFFQKMDRNQDGVVTIDEFLETCQKDE 243 V FF+++D++QDG +T EF++ + Sbjct: 28 RVMDFFRRIDKDQDGKITRQEFIDGILASK 57 >1N2D-A nrPDB Length = 148 Score = 42.0 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 14/98 (14%), Positives = 36/98 (36%), Gaps = 15/98 (15%) Query: 144 GAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTY 203 G I + L + + +K AF ++D G ++ ++ ++ Sbjct: 65 GLIEVNE--KELDATTKAKTEDFVK-AFQVFDKESTGKVSVGDLRYMLTG---------- 111 Query: 204 PILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 L E V+ + ++ + +G + +F+E + Sbjct: 112 --LGEKLTDAEVDELLKGVEVDSNGEIDYKKFIEDVLR 147 Score = 29.7 bits (65), Expect = 1.3, Method: Composition-based stats. Identities = 19/88 (21%), Positives = 35/88 (39%), Gaps = 3/88 (3%) Query: 168 KWAFNLYDINKDGCITKEEMLAIMKSI-YDMMGRHTYPILREDAPLEHVERFFQKMDRNQ 226 K F L+D G I K+ + +++I Y+ + I+ D+ L Sbjct: 7 KDIFTLFDKKGQGAIAKDSLGDYLRAIGYNPTNQLVQDIINADSSLRDASSLTLDQ-ITG 65 Query: 227 DGVVTIDEFLETCQ-KDENIMNSMQLFE 253 V E T + K E+ + + Q+F+ Sbjct: 66 LIEVNEKELDATTKAKTEDFVKAFQVFD 93 >1BU3-A nrPDB Length = 109 Score = 42.0 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 15/83 (18%), Positives = 32/83 (38%), Gaps = 9/83 (10%) Query: 159 LRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERF 218 L + +K AF + D +K G I ++E+ ++ + + F Sbjct: 36 LTAKSADDIKKAFFVIDQDKSGFIEEDELKLFLQ---------VFSAGARALTDAETKAF 86 Query: 219 FQKMDRNQDGVVTIDEFLETCQK 241 + D + DG + +DE+ + Sbjct: 87 LKAGDSDGDGAIGVDEWAALVKA 109 Score = 35.8 bits (81), Expect = 0.019, Method: Composition-based stats. Identities = 17/83 (20%), Positives = 32/83 (38%), Gaps = 3/83 (3%) Query: 114 FKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFED---FVVGLSILLRGTVHEKLKWA 170 +K +++ + F D D +G I ++ F+ S R + K Sbjct: 27 YKAFFAKVGLTAKSADDIKKAFFVIDQDKSGFIEEDELKLFLQVFSAGARALTDAETKAF 86 Query: 171 FNLYDINKDGCITKEEMLAIMKS 193 D + DG I +E A++K+ Sbjct: 87 LKAGDSDGDGAIGVDEWAALVKA 109 >2LVV-A nrPDB Length = 226 Score = 41.6 bits (96), Expect = 4e-04, Method: Composition-based stats. Identities = 26/149 (17%), Positives = 45/149 (30%), Gaps = 19/149 (12%) Query: 95 SLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDA--------DGNGAI 146 L++ F L + Y T + AFD G G Sbjct: 55 ELFKQFDTNGTGKLGFREVLDGCYGILKLDEFTTHLPDIVQRAFDKAKDLGNKVKGVGEE 114 Query: 147 HFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPIL 206 +F+ +L +L F+ D + + +E + + + + Sbjct: 115 DLVEFLEFRLMLCYIYDIFELTVMFDTMDKDGSLLLELQEFKEALPKL-----KEWGVDI 169 Query: 207 REDAPLEHVERFFQKMDRNQDGVVTIDEF 235 + F ++D N GVVT DEF Sbjct: 170 TDATT------VFNEIDTNGSGVVTFDEF 192 Score = 27.0 bits (58), Expect = 7.8, Method: Composition-based stats. Identities = 9/40 (22%), Positives = 15/40 (37%) Query: 200 RHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETC 239 R P ++ F++ D N G + E L+ C Sbjct: 38 RCAIPRDKDAESKSRRIELFKQFDTNGTGKLGFREVLDGC 77 >1SJJ-A nrPDB Length = 863 Score = 41.2 bits (95), Expect = 4e-04, Method: Composition-based stats. Identities = 20/132 (15%), Positives = 53/132 (40%), Gaps = 8/132 (6%) Query: 66 ELELSTVRHQPEGLDQ---LQAQTKFTKKELQSLYRGF--KNECPTGLVDEDTFKLIYSQ 120 E L+T+ ++ + +++++ F + TG++D + F+ Sbjct: 694 EQLLTTIARTINEVENQILTRDAKGISQEQMNEFRASFNHFDRKKTGMMDCEDFRACLIS 753 Query: 121 FFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKD 179 +A + + D + G + F+ F+ +S T +++ +F + +K+ Sbjct: 754 MGYNMGEAEFA-RIMSIVDPNRMGVVTFQAFIDFMSRETADTDTADQVMASFKILAGDKN 812 Query: 180 GCITKEEMLAIM 191 IT +E+ + Sbjct: 813 -YITVDELRREL 823 Score = 28.1 bits (61), Expect = 3.4, Method: Composition-based stats. Identities = 24/109 (22%), Positives = 39/109 (35%), Gaps = 12/109 (11%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSI 194 FN FD G + EDF L + + ++ D N+ G +T ++ Sbjct: 731 FNHFDRKKTGMMDCEDFRACLISMGYNMGEAEFARIMSIVDPNRMGVVT-------FQAF 783 Query: 195 YDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDE 243 D M R T D + + D+N +T+DE D+ Sbjct: 784 IDFMSRETADTDTADQVMASFK--ILAGDKN---YITVDELRRELPPDQ 827 >6FSA-D nrPDB Length = 199 Score = 41.2 bits (95), Expect = 5e-04, Method: Composition-based stats. Identities = 15/94 (15%), Positives = 33/94 (35%), Gaps = 16/94 (17%) Query: 147 HFEDFVVGLSILLRGT---VHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTY 203 F+ F+ L + + +E ++D +G + E+ RH Sbjct: 114 DFDTFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAEL------------RHVL 161 Query: 204 PILREDAPLEHVERFFQKMDRNQDGVVTIDEFLE 237 L E + VE+ + +G + + F++ Sbjct: 162 ATLGEKLTEDEVEKLMA-GQEDSNGCINYEAFVK 194 >5TBY-C nrPDB Length = 195 Score = 40.8 bits (94), Expect = 5e-04, Method: Composition-based stats. Identities = 24/162 (14%), Positives = 50/162 (30%), Gaps = 27/162 (16%) Query: 87 KFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDA---TTYAHFLFNAFDADGN 143 +FT ++++ F T + K+ Y Q A + Sbjct: 45 EFTPEQIEEFKEAFMLFDRT---PKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQ 101 Query: 144 GAI-----HFEDFVVGLSILLRGT---VHEKLKWAFNLYDINKDGCITKEEMLAIMKSIY 195 + FE F+ L + + +E ++D +G + E+ Sbjct: 102 EELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAEL-------- 153 Query: 196 DMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLE 237 RH L E + VE+ + +G + + F++ Sbjct: 154 ----RHVLATLGERLTEDEVEKLMA-GQEDSNGCINYEAFVK 190 >2OS8-B nrPDB Length = 157 Score = 40.8 bits (94), Expect = 6e-04, Method: Composition-based stats. Identities = 27/131 (20%), Positives = 56/131 (42%), Gaps = 8/131 (6%) Query: 86 TKFTKKELQSLYRGFKNECPT--GLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGN 143 TK +K++Q + F G +D + K ++S D L + Sbjct: 11 TKLPQKQIQEMKEAFTMIDQNRDGFIDINDLKEMFSSLGRTPDDKELTAML-----KEAP 65 Query: 144 GAIHFEDFVVGLSILLRGTVHEK-LKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHT 202 G ++F F+ S L GT E+ ++ AF ++D + E + +++++ D + Sbjct: 66 GPLNFTMFLSIFSDKLSGTDSEETIRNAFGMFDELDTKKLNIEYIKDLLENMGDNFNKDE 125 Query: 203 YPILREDAPLE 213 + ++AP+E Sbjct: 126 MRMTFKEAPVE 136 Score = 32.7 bits (73), Expect = 0.15, Method: Composition-based stats. Identities = 17/91 (18%), Positives = 36/91 (39%), Gaps = 9/91 (9%) Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDR 224 +++K AF + D N+DG I ++ + S+ + ++AP F + Sbjct: 19 QEMKEAFTMIDQNRDGFIDINDLKEMFSSLGRTPDDKELTAMLKEAPGPLNFTMFLSI-- 76 Query: 225 NQDGVVTIDEFLETCQKDENIMNSMQLFENV 255 + L +E I N+ +F+ + Sbjct: 77 -------FSDKLSGTDSEETIRNAFGMFDEL 100 >1DFK-Y nrPDB Length = 139 Score = 40.1 bits (92), Expect = 8e-04, Method: Composition-based stats. Identities = 26/129 (20%), Positives = 55/129 (42%), Gaps = 8/129 (6%) Query: 88 FTKKELQSLYRGF--KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGA 145 +K++Q + F + G V ++ K I Q D L + G Sbjct: 1 LPQKQIQEMKEAFSMIDVDRDGFVSKEDIKAISEQLGRAPDDKELTAML-----KEAPGP 55 Query: 146 IHFEDFVVGLSILLRGTVHEK-LKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYP 204 ++F F+ S L GT E+ ++ AF ++D + + E + +++++ D + Sbjct: 56 LNFTMFLSIFSDKLSGTDSEETIRNAFAMFDEQETKKLNIEYIKDLLENMGDNFNKDEMR 115 Query: 205 ILREDAPLE 213 + ++AP+E Sbjct: 116 MTFKEAPVE 124 Score = 32.4 bits (72), Expect = 0.23, Method: Composition-based stats. Identities = 18/89 (20%), Positives = 41/89 (46%), Gaps = 9/89 (10%) Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDR 224 +++K AF++ D+++DG ++KE++ AI + + + ++AP F + Sbjct: 7 QEMKEAFSMIDVDRDGFVSKEDIKAISEQLGRAPDDKELTAMLKEAPGPLNFTMFLSI-- 64 Query: 225 NQDGVVTIDEFLETCQKDENIMNSMQLFE 253 + L +E I N+ +F+ Sbjct: 65 -------FSDKLSGTDSEETIRNAFAMFD 86 >3BOW-B nrPDB Length = 184 Score = 40.1 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 21/127 (16%), Positives = 47/127 (37%), Gaps = 25/127 (19%) Query: 132 HFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIM 191 + D+D G + FE+F + + +K + + +D ++ G I E+ Sbjct: 61 RSMVAVMDSDTTGKLGFEEFKYLWNNI------KKWQGIYKRFDTDRSGTIGSNELPGAF 114 Query: 192 KSIYDMMGRHTYPILREDAPLE--------------HVERFFQKM---DRNQDGVV--TI 232 ++ + +H Y ++ E ++ F+ D+N G + I Sbjct: 115 EAAGFHLNQHIYSMIIRRYSDETGNMDFDNFISCLVRLDAMFRAFRSLDKNGTGQIQVNI 174 Query: 233 DEFLETC 239 E+L+ Sbjct: 175 QEWLQLT 181 >3I5I-C nrPDB Length = 159 Score = 40.1 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 16/91 (17%), Positives = 31/91 (34%), Gaps = 14/91 (15%) Query: 155 LSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEH 214 +S GT ++ AF +D G I+ E+ ++K L E + Sbjct: 75 MSSKDTGTAADEFMEAFKTFDREGQGLISSAEIRNVLKM------------LGERITEDQ 122 Query: 215 VERFFQKMDR--NQDGVVTIDEFLETCQKDE 243 F D + DG + ++ ++ Sbjct: 123 CNDIFTFCDIREDIDGNIKYEDLMKKVMAGP 153 >3CS1-A nrPDB Length = 219 Score = 40.1 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 32/192 (16%), Positives = 64/192 (33%), Gaps = 21/192 (10%) Query: 54 SAAPQGSDSSDSELELSTVRHQPEGLDQL--QAQTKFTKKELQSLYRGFKNECPTGLVDE 111 S + +G S + + E + Q + +T K+ L++ F L + Sbjct: 9 STSDKGLASDKDGKKAKDRKEAWERIRQAIPREKTAEAKQRRIELFKKFDKNETGKLCYD 68 Query: 112 DTFKLIYSQFFPQGDATTYAHFLFNAFDA--------DGNGAIHFEDFVVGLSILLRGTV 163 + + + AFD + G+ F +F+ +L Sbjct: 69 EVYSGCLEVLKLDEFTSRVRDITKRAFDKSRTLGSKLENKGSEDFVEFLEFRLMLCYIYD 128 Query: 164 HEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMD 223 +L F+ D + + + +EE + + + P F+++D Sbjct: 129 FFELTVMFDEIDASGNMLVDEEEFKRAVPKLEAWGAKVEDPAA-----------LFKELD 177 Query: 224 RNQDGVVTIDEF 235 +N G VT DEF Sbjct: 178 KNGTGSVTFDEF 189 Score = 33.9 bits (76), Expect = 0.066, Method: Composition-based stats. Identities = 17/61 (27%), Positives = 26/61 (42%), Gaps = 2/61 (3%) Query: 100 FKNECPTG--LVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSI 157 F +G LVDE+ FK + G LF D +G G++ F++F S Sbjct: 136 FDEIDASGNMLVDEEEFKRAVPKLEAWGAKVEDPAALFKELDKNGTGSVTFDEFAAWASA 195 Query: 158 L 158 + Sbjct: 196 V 196 >1TIZ-A nrPDB Length = 67 Score = 39.7 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 11/65 (16%), Positives = 27/65 (41%) Query: 131 AHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAI 190 A +F FD + +G + ++F E + F D++ +G + +E + Sbjct: 3 AKRVFEKFDKNKDGKLSLDEFREVALAFSPYFTQEDIVKFFEEIDVDGNGELNADEFTSC 62 Query: 191 MKSIY 195 ++ + Sbjct: 63 IEKML 67 Score = 38.5 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 17/74 (22%), Positives = 32/74 (43%), Gaps = 12/74 (16%) Query: 168 KWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQD 227 K F +D NKDG ++ +E + + E + +FF+++D + + Sbjct: 4 KRVFEKFDKNKDGKLSLDEFREVALAFSPYF------------TQEDIVKFFEEIDVDGN 51 Query: 228 GVVTIDEFLETCQK 241 G + DEF +K Sbjct: 52 GELNADEFTSCIEK 65 >1KFU-L nrPDB Length = 699 Score = 39.7 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 14/120 (11%), Positives = 45/120 (37%), Gaps = 19/120 (15%) Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKS 193 + + D+DG+G + ++F + + + +K + + D+++ G + EM ++ Sbjct: 579 MVDMLDSDGSGKLGLKEFYILWTKI------QKYQKIYREIDVDRSGTMNSYEMRKALEE 632 Query: 194 IYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQLFE 253 M + ++ + + ++ D F+ + E + + + Sbjct: 633 AGFKMPCQLHQVIVARFADDQL-------------IIDFDNFVRCLVRLETLFKIFKQLD 679 Score = 30.8 bits (68), Expect = 0.67, Method: Composition-based stats. Identities = 16/118 (13%), Positives = 37/118 (31%), Gaps = 18/118 (15%) Query: 126 DATTYAHFLFNAFDADG------NGAIH--FEDFVVGLSILLRGTVHEKLKWAFNLYDIN 177 + F F + I E+F + + + ++ F Sbjct: 489 EPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEF-----DISEDDIDDGVRRLFAQL-AG 542 Query: 178 KDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEF 235 +D I+ E+ I++ + I + +E + +D + G + + EF Sbjct: 543 EDAEISAFELQTILRRVLA----KRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEF 596 >2M1U-A nrPDB Length = 93 Score = 39.3 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 16/74 (21%), Positives = 26/74 (35%), Gaps = 13/74 (17%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRN 225 +L AF +D + DG ++ EE I++ M + FF+ D N Sbjct: 27 QLIEAFYNFDGDYDGFVSVEEFRGIIRDGLPM-------------TEAEITEFFEAADPN 73 Query: 226 QDGVVTIDEFLETC 239 G + F Sbjct: 74 NTGFIDYKAFAAML 87 Score = 37.0 bits (84), Expect = 0.009, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 23/67 (34%), Gaps = 4/67 (5%) Query: 91 KELQSLYRGFKNECPT--GLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHF 148 E L F N G V + F+ I P +A F A D + G I + Sbjct: 23 DEKTQLIEAFYNFDGDYDGFVSVEEFRGIIRDGLPMTEAE--ITEFFEAADPNNTGFIDY 80 Query: 149 EDFVVGL 155 + F L Sbjct: 81 KAFAAML 87 Score = 33.9 bits (76), Expect = 0.074, Method: Composition-based stats. Identities = 15/60 (25%), Positives = 25/60 (41%), Gaps = 1/60 (1%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSI 194 F FD D +G + E+F G+ ++ F D N G I + A++ S+ Sbjct: 32 FYNFDGDYDGFVSVEEF-RGIIRDGLPMTEAEITEFFEAADPNNTGFIDYKAFAAMLYSV 90 >3JBH-C nrPDB Length = 156 Score = 39.3 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 19/108 (17%), Positives = 37/108 (34%), Gaps = 15/108 (13%) Query: 139 DADGNGAIHFEDFVVGLSILLRGT---VHEKLKWAFNLYDINKDGCITKEEMLAIMKSIY 195 D G + E+F+ S + + E +YD ++G + E+ ++ S Sbjct: 55 DKRGEKKLTLEEFLPIFSQIKKEKEVGTLEDFMEGLKVYDKAENGTMLAAELAHVLLS-- 112 Query: 196 DMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDE 243 L E E + D + DG + + F++T Sbjct: 113 ----------LGERLTDIECEEIMRVCDEDDDGFLKYEPFVKTIIAGP 150 Score = 32.7 bits (73), Expect = 0.14, Method: Composition-based stats. Identities = 18/94 (19%), Positives = 38/94 (40%), Gaps = 16/94 (17%) Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDR 224 EK + F +YD +G I ++ +++S L L V++ D+ Sbjct: 10 EKAREHFEIYDWEGEGKIDARDLGDLLRS------------LDCKPTLAMVKKN-GGSDK 56 Query: 225 NQDGVVTIDEFL---ETCQKDENIMNSMQLFENV 255 + +T++EFL +K++ + E + Sbjct: 57 RGEKKLTLEEFLPIFSQIKKEKEVGTLEDFMEGL 90 Score = 30.8 bits (68), Expect = 0.52, Method: Composition-based stats. Identities = 15/80 (18%), Positives = 29/80 (36%), Gaps = 2/80 (2%) Query: 108 LVDEDTFKLIYSQFFPQGDATTYAHFL--FNAFDADGNGAIHFEDFVVGLSILLRGTVHE 165 + + F I+SQ + + T F+ +D NG + + L L Sbjct: 61 KLTLEEFLPIFSQIKKEKEVGTLEDFMEGLKVYDKAENGTMLAAELAHVLLSLGERLTDI 120 Query: 166 KLKWAFNLYDINKDGCITKE 185 + + + D + DG + E Sbjct: 121 ECEEIMRVCDEDDDGFLKYE 140 >4I5K-A nrPDB Length = 285 Score = 39.3 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 30/179 (16%), Positives = 59/179 (32%), Gaps = 12/179 (6%) Query: 60 SDSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYS 119 S L T+ E D Q F+ + +Y F D + S Sbjct: 82 STEIRKSNFLQTLALLEEEEDINQITDYFSYEHFYVIYCKFWELDTDH--DLYISQADLS 139 Query: 120 QFFPQGDATTYAHFLFNAFDADG-----NGAIHFEDFVVGLSILLRGTVHEKLKWAFNLY 174 ++ Q ++ +F+ G G + + DFV L +++ F Sbjct: 140 RYNDQASSSRIIERIFSGAVTRGKTIQKEGRMSYADFVWFLISEEDKRNPTSIEYWFRCM 199 Query: 175 DINKDGCITKEEMLAIMKS-IYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTI 232 D++ DG ++ E+ + M P+ D + ++ + DG +T+ Sbjct: 200 DVDGDGVLSMYELEYFYEEQCERMEAMGIEPLPFHDLLCQMLDLVKPAV----DGKITL 254 Score = 28.5 bits (62), Expect = 3.1, Method: Composition-based stats. Identities = 27/190 (14%), Positives = 62/190 (32%), Gaps = 23/190 (12%) Query: 56 APQGSDSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFK 115 P D D+ L+ ++ PE + T ++ ++ R + + + + + F Sbjct: 34 IPLLQDVVDTHPGLTFLKDAPEFHSRY--ITTVIQRIFYTVNRSWSGKITSTEIRKSNFL 91 Query: 116 LIYSQFFPQGDATTYAHFL-----------FNAFDADGNGAIHFEDFVVGLSILLRGTVH 164 + + D + F D D + I D LS Sbjct: 92 QTLALLEEEEDINQITDYFSYEHFYVIYCKFWELDTDHDLYISQAD----LSRYNDQASS 147 Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDR 224 ++ ++ G +T+ + + + + +E +F+ MD Sbjct: 148 SRIIE--RIF----SGAVTRGKTIQKEGRMSYADFVWFLISEEDKRNPTSIEYWFRCMDV 201 Query: 225 NQDGVVTIDE 234 + DGV+++ E Sbjct: 202 DGDGVLSMYE 211 >5I2L-A nrPDB Length = 120 Score = 39.3 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 17/94 (18%), Positives = 36/94 (38%), Gaps = 20/94 (21%) Query: 143 NGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHT 202 N F++F R + + ++ F YD +DG I E+ +M+ + Sbjct: 17 NPYTEFKEF-------SRKQI-KDMEKMFKQYDAGRDGFIDLMELKLMMEKLGAPQTHLG 68 Query: 203 YPILREDAPLEHVERFFQKMDRNQDGVVTIDEFL 236 ++ +++D + D ++ EFL Sbjct: 69 ------------LKNMIKEVDEDFDSKLSFREFL 90 Score = 33.1 bits (74), Expect = 0.11, Method: Composition-based stats. Identities = 14/83 (16%), Positives = 34/83 (40%), Gaps = 3/83 (3%) Query: 86 TKFTKKELQSLYRGFK--NECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGN 143 +F++K+++ + + FK + G +D KL+ + + + D D + Sbjct: 23 KEFSRKQIKDMEKMFKQYDAGRDGFIDLMELKLMMEKLGAPQTHLGLKN-MIKEVDEDFD 81 Query: 144 GAIHFEDFVVGLSILLRGTVHEK 166 + F +F++ G + E Sbjct: 82 SKLSFREFLLIFRKAAAGELQED 104 Score = 32.4 bits (72), Expect = 0.20, Method: Composition-based stats. Identities = 14/62 (22%), Positives = 24/62 (38%) Query: 132 HFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIM 191 +F +DA +G I + + + L H LK D + D ++ E L I Sbjct: 34 EKMFKQYDAGRDGFIDLMELKLMMEKLGAPQTHLGLKNMIKEVDEDFDSKLSFREFLLIF 93 Query: 192 KS 193 + Sbjct: 94 RK 95 Score = 28.5 bits (62), Expect = 3.2, Method: Composition-based stats. Identities = 8/43 (18%), Positives = 19/43 (44%) Query: 199 GRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 +T ++ +E+ F++ D +DG + + E +K Sbjct: 17 NPYTEFKEFSRKQIKDMEKMFKQYDAGRDGFIDLMELKLMMEK 59 >3DF0-A nrPDB Length = 714 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 14/152 (9%), Positives = 50/152 (32%), Gaps = 26/152 (17%) Query: 109 VDEDTFKLIYSQFFPQGDATTYA-------HFLFNAFDADGNGAIHFEDFVVGLSILLRG 161 + + I + + + + + D DG+G + ++F + + + Sbjct: 548 ISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWTKI--- 604 Query: 162 TVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQK 221 +K + + D+++ G + EM ++ + + ++ + + Sbjct: 605 ---QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDEL------ 655 Query: 222 MDRNQDGVVTIDEFLETCQKDENIMNSMQLFE 253 ++ D F+ + E + + + Sbjct: 656 -------IIDFDNFVRCLVRLEILFKIFKQLD 680 Score = 30.4 bits (67), Expect = 0.71, Method: Composition-based stats. Identities = 20/89 (22%), Positives = 31/89 (34%), Gaps = 9/89 (10%) Query: 94 QSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVV 153 Q +YR + +G ++ + + + H + A AD I F++FV Sbjct: 608 QKIYRE-IDVDRSGTMNSYEMRKALEEAGFKLPCQL--HQVIVARFADDELIIDFDNFVR 664 Query: 154 GLSILLRGTVHEKLKWAFNLYDINKDGCI 182 L L E L F D G I Sbjct: 665 CLVRL------EILFKIFKQLDPENTGTI 687 Score = 29.3 bits (64), Expect = 1.8, Method: Composition-based stats. Identities = 10/57 (17%), Positives = 22/57 (38%), Gaps = 4/57 (7%) Query: 179 DGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEF 235 D I+ E+ I++ + I + +E + +D + G + + EF Sbjct: 545 DAEISAFELQTILRRVLA----KREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEF 597 >2FCE-A nrPDB Length = 70 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 11/77 (14%), Positives = 29/77 (37%), Gaps = 12/77 (15%) Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDR 224 E AF ++D G ++ ++ ++ L E V+ + ++ Sbjct: 5 EDFVKAFQVFDKESTGKVSVGDLRYMLTG------------LGEKLTDAEVDELLKGVEV 52 Query: 225 NQDGVVTIDEFLETCQK 241 + +G + +F+E + Sbjct: 53 DSNGEIDYKKFIEDVLR 69 >5VT9-A nrPDB Length = 152 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 24/118 (20%), Positives = 43/118 (36%), Gaps = 4/118 (3%) Query: 92 ELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDF 151 E +Y F G V ++ Q + F D F+ F Sbjct: 18 EADEMYARFNARASGGKVSTGDAMILARQLG--LAPSYADKQAFEEKSGDNLDYASFQKF 75 Query: 152 VVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILRED 209 V G S + E L AF +D++K G +T+++M I+ + + + + L + Sbjct: 76 V-GTSTHPEDNI-EDLVEAFAYFDVSKHGYLTRKQMGNILMTYGEPLTTEEFNALAAE 131 >1KFX-S nrPDB Length = 184 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 26/176 (14%), Positives = 57/176 (32%), Gaps = 33/176 (18%) Query: 91 KELQSLYRGFKNECPTGL-VDEDTFKLIYSQFF---PQGDATTYA----HFLFNAFDADG 142 +E++ R F + V I ++ P + + D+D Sbjct: 12 EEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDT 71 Query: 143 NGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHT 202 G + FE+F + + R + +D ++ G I E+ ++ + H Sbjct: 72 TGKLGFEEFKYLWNNIKRWQA------IYKQFDTDRSGTICSSELPGAFEAAGFHLNEHL 125 Query: 203 YPILREDAPLE--------------HVERFFQKM---DRNQDGVV--TIDEFLETC 239 Y ++ E ++ F+ D++ G + I E+L+ Sbjct: 126 YNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLT 181 >2PMY-A nrPDB Length = 91 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 17/66 (25%), Positives = 32/66 (48%), Gaps = 5/66 (7%) Query: 91 KELQSLYRGF--KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHF 148 +EL L F + +G ++ + F+ + ++ + A +F DAD +GAI F Sbjct: 24 EELARLRSVFAACDANRSGRLEREEFRALCTELRVRPAD---AEAVFQRLDADRDGAITF 80 Query: 149 EDFVVG 154 ++F G Sbjct: 81 QEFARG 86 Score = 36.6 bits (83), Expect = 0.010, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 29/73 (39%), Gaps = 14/73 (19%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRN 225 +L+ F D N+ G + +EE A+ + E FQ++D + Sbjct: 28 RLRSVFAACDANRSGRLEREEFRALCTELRVRPA--------------DAEAVFQRLDAD 73 Query: 226 QDGVVTIDEFLET 238 +DG +T EF Sbjct: 74 RDGAITFQEFARG 86 Score = 31.2 bits (69), Expect = 0.39, Method: Composition-based stats. Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 2/63 (3%) Query: 124 QGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCIT 183 G+ +F A DA+ +G + E+F + L + F D ++DG IT Sbjct: 22 DGEELARLRSVFAACDANRSGRLEREEFRALCTELRVRPADAEA--VFQRLDADRDGAIT 79 Query: 184 KEE 186 +E Sbjct: 80 FQE 82 >2MBX-A nrPDB Length = 109 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 14/101 (13%), Positives = 36/101 (35%), Gaps = 11/101 (10%) Query: 141 DGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGR 200 G+ + F + + + +K F + D +K + ++E+ +++ Sbjct: 20 KAEGSFDHKAFFTKVGLAAKSPAD--IKKVFEIIDQDKSDFVEEDELKLFLQN------- 70 Query: 201 HTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 + + F + D + DG + +DEF + Sbjct: 71 --FSAGARALSDAETKVFLKAGDSDGDGKIGVDEFGAMIKA 109 >1BOD-A nrPDB Length = 74 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 20/80 (25%), Positives = 36/80 (45%), Gaps = 10/80 (12%) Query: 162 TVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQK 221 E+LK F YD DG + K ++ + +P L + ++ F++ Sbjct: 2 KSPEELKGIFEKYDKEGDG--------QLSKEELKLLLQTEFPSLLKGMST--LDELFEE 51 Query: 222 MDRNQDGVVTIDEFLETCQK 241 +D+N DG V+ +EF +K Sbjct: 52 LDKNGDGEVSFEEFQVLVKK 71 Score = 32.4 bits (72), Expect = 0.21, Method: Composition-based stats. Identities = 15/63 (23%), Positives = 30/63 (47%) Query: 89 TKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHF 148 + +EL+ ++ + E L E+ L+ ++F + LF D +G+G + F Sbjct: 3 SPEELKGIFEKYDKEGDGQLSKEELKLLLQTEFPSLLKGMSTLDELFEELDKNGDGEVSF 62 Query: 149 EDF 151 E+F Sbjct: 63 EEF 65 >2LUC-A nrPDB Length = 105 Score = 38.5 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 20/78 (25%), Positives = 31/78 (39%), Gaps = 11/78 (14%) Query: 165 EKLKWAFNLYDINKDGC---ITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQK 221 E L F Y KDG ++K E L+ M + ++ ++R +K Sbjct: 15 ESLIAVFQKY-AGKDGYNYTLSKTEFLSFMNTELAAFTKNQKDP-------GVLDRMMKK 66 Query: 222 MDRNQDGVVTIDEFLETC 239 +D N DG + EFL Sbjct: 67 LDTNSDGQLDFSEFLNLI 84 Score = 34.3 bits (77), Expect = 0.053, Method: Composition-based stats. Identities = 10/76 (13%), Positives = 26/76 (34%), Gaps = 8/76 (10%) Query: 89 TKKELQSLYRGFKN----ECPTGLVDEDTFKLI----YSQFFPQGDATTYAHFLFNAFDA 140 T++ ++SL F+ + + + F + F + D Sbjct: 10 TERCIESLIAVFQKYAGKDGYNYTLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLDT 69 Query: 141 DGNGAIHFEDFVVGLS 156 + +G + F +F+ + Sbjct: 70 NSDGQLDFSEFLNLIG 85 >4OCI-A nrPDB Length = 146 Score = 38.1 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 27/150 (18%), Positives = 60/150 (40%), Gaps = 23/150 (15%) Query: 91 KELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAI---H 147 ++L+ + F + G + + F+ + + + A + N + Sbjct: 6 EDLKESFLLFDGD-GDGYLTLNEFESLVRVLGVVMETSAIAST------YNSNSKVRGMS 58 Query: 148 FEDFVVGLSILLRGTVH-EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPIL 206 +E F S L + + +++K A N+ D +K G I E+ I+ +I Sbjct: 59 YELFTSCFSQLKTKSFNKDEIKTAINVLDKDKKGFIPAIELRRILSTI------------ 106 Query: 207 REDAPLEHVERFFQKMDRNQDGVVTIDEFL 236 ++ + + F M ++ GVV +D+F+ Sbjct: 107 GDNMEQKEITDLFTFMGIDEQGVVKVDDFI 136 Score = 34.3 bits (77), Expect = 0.047, Method: Composition-based stats. Identities = 11/38 (28%), Positives = 22/38 (57%) Query: 161 GTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMM 198 +E LK +F L+D + DG +T E ++++ + +M Sbjct: 2 QKHNEDLKESFLLFDGDGDGYLTLNEFESLVRVLGVVM 39 Score = 27.3 bits (59), Expect = 6.3, Method: Composition-based stats. Identities = 8/28 (28%), Positives = 15/28 (53%) Query: 213 EHVERFFQKMDRNQDGVVTIDEFLETCQ 240 E ++ F D + DG +T++EF + Sbjct: 6 EDLKESFLLFDGDGDGYLTLNEFESLVR 33 >2N8Y-A nrPDB Length = 153 Score = 38.1 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 20/115 (17%), Positives = 49/115 (42%), Gaps = 12/115 (10%) Query: 86 TKFTKKELQSLYRGF--KNECPTGLVDEDTFKLIYSQFF------PQGDATTYAHFLFNA 137 + +++++ F + +G + + FK PQG+A +A + + Sbjct: 2 SSISQEQMNEFRASFNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQGEAE-FA-RIMSI 59 Query: 138 FDADGNGAIHFEDFVVGLSILLRGT-VHEKLKWAFNLYDINKDGCITKEEMLAIM 191 D + G + F+ F+ +S T +++ +F + +K+ IT +E+ + Sbjct: 60 VDPNRLGVVTFQAFIDFMSRETADTDTADQVMASFKILAGDKN-YITMDELRREL 113 Score = 28.1 bits (61), Expect = 3.9, Method: Composition-based stats. Identities = 25/114 (21%), Positives = 41/114 (35%), Gaps = 17/114 (14%) Query: 135 FNAFDADGNGAIHFEDFVVGLSILLRG-----TVHEKLKWAFNLYDINKDGCITKEEMLA 189 FN FD D +G + E+F L L + ++ D N+ G +T Sbjct: 16 FNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQGEAEFARIMSIVDPNRLGVVT------ 69 Query: 190 IMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDE 243 ++ D M R T D + + D+N +T+DE D+ Sbjct: 70 -FQAFIDFMSRETADTDTADQVMASFK--ILAGDKN---YITMDELRRELPPDQ 117 >1ZFS-A nrPDB Length = 93 Score = 38.1 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 12/62 (19%), Positives = 27/62 (43%), Gaps = 8/62 (12%) Query: 176 INKDGC-ITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDE 234 D ++K+E+ ++++ L + V++ +++D N DG V E Sbjct: 21 KEGDKYKLSKKELKDLLQT-------ELSSFLDVQKDADAVDKIMKELDENGDGEVDFQE 73 Query: 235 FL 236 F+ Sbjct: 74 FV 75 Score = 38.1 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 11/48 (22%), Positives = 21/48 (43%) Query: 111 EDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSIL 158 +D + S F + D +G+G + F++FVV ++ L Sbjct: 34 KDLLQTELSSFLDVQKDADAVDKIMKELDENGDGEVDFQEFVVLVAAL 81 >3A8R-A nrPDB Length = 179 Score = 38.1 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 23/154 (14%), Positives = 54/154 (35%), Gaps = 19/154 (12%) Query: 98 RGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAI-------HFED 150 + F G++ F + +A +F++ A G + +D Sbjct: 32 KRFNQLQVDGVLLRSRFGKCIGMDG----SDEFAVQMFDSL-ARKRGIVKQVLTKDELKD 86 Query: 151 FVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDA 210 F L+ +L+ F++ D N DG +T EE+ I+ + ++ Sbjct: 87 FYEQLT---DQGFDNRLRTFFDMVDKNADGRLTAEEVKEII----ALSASANKLSKIKER 139 Query: 211 PLEHVERFFQKMDRNQDGVVTIDEFLETCQKDEN 244 E+ +++D G + +++ + + Sbjct: 140 ADEYTALIMEELDPTNLGYIEMEDLEALLLQSPS 173 >2W4G-C nrPDB Length = 145 Score = 37.7 bits (86), Expect = 0.005, Method: Composition-based stats. Identities = 14/96 (14%), Positives = 32/96 (33%), Gaps = 16/96 (16%) Query: 145 AIHFEDFVVGLSILLRGTVH---EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRH 201 I FE+F+ L E ++D +G + E+ ++ ++ + M Sbjct: 58 KITFEEFLPMLQAAANNKDQGTFEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMTEE 117 Query: 202 TYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLE 237 L K + +G + + F++ Sbjct: 118 EVEEL-------------MKGQEDSNGCINYEAFVK 140 Score = 37.4 bits (85), Expect = 0.007, Method: Composition-based stats. Identities = 17/98 (17%), Positives = 35/98 (35%), Gaps = 19/98 (19%) Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDR 224 K AF L+D D IT ++ I++++ + + E + Sbjct: 4 NDFKEAFLLFDRTGDAKITLSQVGDIVRALGQNPTNAEINKILGNPSKEEMNAK------ 57 Query: 225 NQDGVVTIDEFLETCQKD---------ENIMNSMQLFE 253 +T +EFL Q E+ + +++F+ Sbjct: 58 ----KITFEEFLPMLQAAANNKDQGTFEDFVEGLRVFD 91 Score = 29.7 bits (65), Expect = 1.3, Method: Composition-based stats. Identities = 18/90 (20%), Positives = 30/90 (33%), Gaps = 9/90 (10%) Query: 101 KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFL--FNAFDADGNGAI---HFEDFVVGL 155 K E + + F + D T+ F+ FD +GNG + + L Sbjct: 51 KEEMNAKKITFEEFLPMLQAAANNKDQGTFEDFVEGLRVFDKEGNGTVMGAELRHVLATL 110 Query: 156 SILLRGTVHEKLKWAFNLYDINKDGCITKE 185 + E+L + +GCI E Sbjct: 111 GEKMTEEEVEELMKG----QEDSNGCINYE 136 >2L50-A nrPDB Length = 102 Score = 37.4 bits (85), Expect = 0.006, Method: Composition-based stats. Identities = 10/43 (23%), Positives = 22/43 (51%) Query: 193 SIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEF 235 S +M+ + +L + + ++ Q +D N DG ++ DE+ Sbjct: 36 SFREMLQKELNHMLSDTGNRKAADKLIQNLDANHDGRISFDEY 78 Score = 28.5 bits (62), Expect = 2.7, Method: Composition-based stats. Identities = 7/41 (17%), Positives = 15/41 (36%) Query: 111 EDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDF 151 + + + A L DA+ +G I F+++ Sbjct: 38 REMLQKELNHMLSDTGNRKAADKLIQNLDANHDGRISFDEY 78 >2KGR-A nrPDB Length = 111 Score = 37.4 bits (85), Expect = 0.007, Method: Composition-based stats. Identities = 15/75 (20%), Positives = 28/75 (37%), Gaps = 14/75 (18%) Query: 166 KLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRN 225 K + FN +D G +T + I+ ++ P + + D + Sbjct: 15 KYRQLFNSHDKTMSGHLTGPQARTIL--------------MQSSLPQAQLASIWNLSDID 60 Query: 226 QDGVVTIDEFLETCQ 240 QDG +T +EF+ Sbjct: 61 QDGKLTAEEFILAMH 75 Score = 32.7 bits (73), Expect = 0.17, Method: Composition-based stats. Identities = 24/85 (28%), Positives = 40/85 (47%), Gaps = 5/85 (5%) Query: 123 PQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHE-KLKWAFNLYDINKDGC 181 PQ Y LFN+ D +G + +IL++ ++ + +L +NL DI++DG Sbjct: 9 PQSSRLKYRQ-LFNSHDKTMSGHLTGPQ---ARTILMQSSLPQAQLASIWNLSDIDQDGK 64 Query: 182 ITKEEMLAIMKSIYDMMGRHTYPIL 206 +T EE + M I M P + Sbjct: 65 LTAEEFILAMHLIDVAMSGQPLPPV 89 >1Q80-A nrPDB Length = 174 Score = 37.4 bits (85), Expect = 0.007, Method: Composition-based stats. Identities = 24/150 (16%), Positives = 49/150 (32%), Gaps = 29/150 (19%) Query: 102 NECPTGLVDEDTFKLIYSQFFPQGD-----ATTYAHFLFNAFDAD-----GNGAIHFEDF 151 + G + F+ + +F + + A L +D G I F Sbjct: 16 DFDKDGAITRMDFESMAERFAKESEMKAEHAKVLMDSLTGVWDNFLTAVAGGKGIDETTF 75 Query: 152 VVGLSILLRGT-----VHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPIL 206 + + +++ V L F D N+D I+++E + Sbjct: 76 INSMKEMVKNPEAKSVVEGPLPLFFRAVDTNEDNNISRDEYGIFFGMLG----------- 124 Query: 207 REDAPLEHVERFFQKMDRNQDGVVTIDEFL 236 F +D N DG+++++EF+ Sbjct: 125 ---LDKTMAPASFDAIDTNNDGLLSLEEFV 151 Score = 29.3 bits (64), Expect = 1.9, Method: Composition-based stats. Identities = 11/51 (21%), Positives = 21/51 (41%), Gaps = 3/51 (5%) Query: 109 VDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILL 159 + D + + + T A F+A D + +G + E+FV+ S Sbjct: 111 ISRDEYGIFFGMLGLDK---TMAPASFDAIDTNNDGLLSLEEFVIAGSDFF 158 Score = 28.1 bits (61), Expect = 4.3, Method: Composition-based stats. Identities = 23/111 (20%), Positives = 39/111 (35%), Gaps = 40/111 (36%) Query: 165 EKLKWAFNLYDINKDGCITK---EEMLAIMKSIYDMMGRHTYPILRE------------- 208 +K+K FN D +KDG IT+ E M +M H ++ Sbjct: 6 QKMKTYFNRIDFDKDGAITRMDFESMAERFAKESEMKAEHAKVLMDSLTGVWDNFLTAVA 65 Query: 209 -----------DAPLEHVER-------------FFQKMDRNQDGVVTIDEF 235 ++ E V+ FF+ +D N+D ++ DE+ Sbjct: 66 GGKGIDETTFINSMKEMVKNPEAKSVVEGPLPLFFRAVDTNEDNNISRDEY 116 >1CB1-A nrPDB Length = 78 Score = 37.0 bits (84), Expect = 0.008, Method: Composition-based stats. Identities = 17/74 (22%), Positives = 37/74 (50%), Gaps = 13/74 (17%) Query: 168 KWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQD 227 K+A D N+ ++KEE+ ++++ + + + ++ FQ++D+N D Sbjct: 15 KYAAKEGDPNQ---LSKEELKQLIQAEFPSLLKGPRT----------LDDLFQELDKNGD 61 Query: 228 GVVTIDEFLETCQK 241 G V+ +EF +K Sbjct: 62 GEVSFEEFQVLVKK 75 Score = 34.7 bits (78), Expect = 0.038, Method: Composition-based stats. Identities = 15/62 (24%), Positives = 27/62 (43%), Gaps = 2/62 (3%) Query: 92 ELQSLYRGFK-NECPTGLVDEDTFKLIYSQFFPQGDATTYA-HFLFNAFDADGNGAIHFE 149 EL+S++ + E + ++ K + FP LF D +G+G + FE Sbjct: 8 ELKSIFEKYAAKEGDPNQLSKEELKQLIQAEFPSLLKGPRTLDDLFQELDKNGDGEVSFE 67 Query: 150 DF 151 +F Sbjct: 68 EF 69 >1NP8-A nrPDB Length = 159 Score = 36.2 bits (82), Expect = 0.013, Method: Composition-based stats. Identities = 17/122 (13%), Positives = 44/122 (36%), Gaps = 19/122 (15%) Query: 132 HFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIM 191 + D+D G + FE+F + + +K + + +D ++ G I E+ Sbjct: 57 RSMVAVMDSDTTGKLGFEEFKYLWNNI------KKWQGIYKRFDTDRSGTIGSNELPGAF 110 Query: 192 KSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQL 251 ++ + +H Y ++ E G + D F+ + + + + + Sbjct: 111 EAAGFHLNQHIYSMIIRRYSDET-------------GNMDFDNFISCLVRLDAMFRAFRS 157 Query: 252 FE 253 + Sbjct: 158 LD 159 >2EC6-B nrPDB Length = 133 Score = 36.2 bits (82), Expect = 0.015, Method: Composition-based stats. Identities = 22/109 (20%), Positives = 47/109 (43%), Gaps = 6/109 (5%) Query: 106 TGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHE 165 G +D + K +S D L + G ++F F+ S L GT E Sbjct: 16 DGFIDINDLKEEFSSLGRTPDDKELTAML-----KEAPGPLNFTMFLSIFSDKLSGTDSE 70 Query: 166 K-LKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLE 213 + ++ AF ++D + + E + +++++ D + + ++AP+E Sbjct: 71 ETIRNAFGMFDEDATKKLNIEYIKDLLENMGDNFNKDEMRMTFKEAPVE 119 Score = 29.7 bits (65), Expect = 1.2, Method: Composition-based stats. Identities = 17/89 (19%), Positives = 34/89 (38%), Gaps = 9/89 (10%) Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDR 224 +++K AF + D N+DG I ++ S+ + ++AP F + Sbjct: 2 QEMKEAFTMIDQNRDGFIDINDLKEEFSSLGRTPDDKELTAMLKEAPGPLNFTMFLSI-- 59 Query: 225 NQDGVVTIDEFLETCQKDENIMNSMQLFE 253 + L +E I N+ +F+ Sbjct: 60 -------FSDKLSGTDSEETIRNAFGMFD 81 >1NSH-A nrPDB Length = 101 Score = 36.2 bits (82), Expect = 0.015, Method: Composition-based stats. Identities = 20/78 (25%), Positives = 31/78 (39%), Gaps = 11/78 (14%) Query: 165 EKLKWAFNLYDINKDGC---ITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQK 221 E L F Y KDG ++K E L+ M + ++ ++R +K Sbjct: 11 ESLIAVFQKY-AGKDGHSVTLSKTEFLSFMNTELAAFTKNQKDP-------GVLDRMMKK 62 Query: 222 MDRNQDGVVTIDEFLETC 239 +D N DG + EFL Sbjct: 63 LDLNSDGQLDFQEFLNLI 80 Score = 34.3 bits (77), Expect = 0.049, Method: Composition-based stats. Identities = 10/76 (13%), Positives = 28/76 (36%), Gaps = 8/76 (10%) Query: 89 TKKELQSLYRGFKN----ECPTGLVDEDTFKLI----YSQFFPQGDATTYAHFLFNAFDA 140 T++ ++SL F+ + + + + F + F + D Sbjct: 6 TERCIESLIAVFQKYAGKDGHSVTLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLDL 65 Query: 141 DGNGAIHFEDFVVGLS 156 + +G + F++F+ + Sbjct: 66 NSDGQLDFQEFLNLIG 81 >2L0P-A nrPDB Length = 94 Score = 35.8 bits (81), Expect = 0.017, Method: Composition-based stats. Identities = 11/62 (17%), Positives = 28/62 (45%), Gaps = 8/62 (12%) Query: 176 INKDGC-ITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDE 234 D ++K+E+ ++++ L ++ V++ +++D N DG V E Sbjct: 22 KEGDKYKLSKKELKELLQT-------ELSGFLDAQKDVDAVDKVMKELDENGDGEVDFQE 74 Query: 235 FL 236 ++ Sbjct: 75 YV 76 Score = 35.8 bits (81), Expect = 0.020, Method: Composition-based stats. Identities = 9/48 (18%), Positives = 21/48 (43%) Query: 111 EDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSIL 158 ++ + S F + D +G+G + F+++VV ++ L Sbjct: 35 KELLQTELSGFLDAQKDVDAVDKVMKELDENGDGEVDFQEYVVLVAAL 82 >3TS5-B nrPDB Length = 161 Score = 35.8 bits (81), Expect = 0.020, Method: Composition-based stats. Identities = 25/130 (19%), Positives = 54/130 (41%), Gaps = 8/130 (6%) Query: 87 KFTKKELQSLYRGFKNECPT--GLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNG 144 + +K +Q + F G +D + K ++S D L + G Sbjct: 16 RLPQKLMQEMKEAFTMIDQNRDGFIDINDLKEMFSSLGRTPDDKELTAML-----KEAPG 70 Query: 145 AIHFEDFVVGLSILLRGTVHEK-LKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTY 203 ++F F+ S L GT E+ ++ AF ++D + E + +++++ D + Sbjct: 71 PLNFTMFLSIFSDKLSGTDSEETIRNAFGMFDELDTKKLNIEYIKDLLENMGDNFNKDEM 130 Query: 204 PILREDAPLE 213 + ++AP+E Sbjct: 131 RMTFKEAPVE 140 Score = 33.1 bits (74), Expect = 0.13, Method: Composition-based stats. Identities = 17/95 (17%), Positives = 37/95 (38%), Gaps = 9/95 (9%) Query: 161 GTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQ 220 + +++K AF + D N+DG I ++ + S+ + ++AP F Sbjct: 19 QKLMQEMKEAFTMIDQNRDGFIDINDLKEMFSSLGRTPDDKELTAMLKEAPGPLNFTMFL 78 Query: 221 KMDRNQDGVVTIDEFLETCQKDENIMNSMQLFENV 255 + + L +E I N+ +F+ + Sbjct: 79 SI---------FSDKLSGTDSEETIRNAFGMFDEL 104 >6DS2-B nrPDB Length = 114 Score = 35.4 bits (80), Expect = 0.023, Method: Composition-based stats. Identities = 7/35 (20%), Positives = 18/35 (51%) Query: 207 REDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 +E+ + +E + +D N D ++ +EF+ + Sbjct: 51 KENKNEKVIEHIMEDLDTNADKQLSFEEFIMLMAR 85 Score = 34.3 bits (77), Expect = 0.053, Method: Composition-based stats. Identities = 10/67 (14%), Positives = 27/67 (40%), Gaps = 6/67 (8%) Query: 108 LVDEDTFKLIYSQ-----FFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGT 162 +++ FK + + + + D + + + FE+F++ ++ L + Sbjct: 31 TLNQGEFKELVRKDLQNFLKKENKNEKVIEHIMEDLDTNADKQLSFEEFIMLMARLTWAS 90 Query: 163 VHEKLKW 169 HEK+ Sbjct: 91 -HEKMHE 96 >5HYD-A nrPDB Length = 99 Score = 35.4 bits (80), Expect = 0.024, Method: Composition-based stats. Identities = 12/61 (19%), Positives = 25/61 (40%), Gaps = 7/61 (11%) Query: 181 CITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQ 240 ++K E+ +++ R L + V++ Q +D N+D V +EF+ Sbjct: 28 KLSKGELKLLLQ-------RELTEFLSCQKETQLVDKIVQDLDANKDNEVDFNEFVVMVA 80 Query: 241 K 241 Sbjct: 81 A 81 Score = 33.9 bits (76), Expect = 0.063, Method: Composition-based stats. Identities = 9/45 (20%), Positives = 19/45 (42%) Query: 114 FKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSIL 158 + ++F T + DA+ + + F +FVV ++ L Sbjct: 38 LQRELTEFLSCQKETQLVDKIVQDLDANKDNEVDFNEFVVMVAAL 82 >5W1A-B nrPDB Length = 155 Score = 35.4 bits (80), Expect = 0.027, Method: Composition-based stats. Identities = 21/108 (19%), Positives = 35/108 (32%), Gaps = 17/108 (15%) Query: 145 AIHFEDFVVGLSILLRGTVH---EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRH 201 I ++F+ S + + E LYD ++G + E+ + + Sbjct: 60 KIKLDEFLPIYSQVKKEKEQGCYEDFIECLKLYDKEENGTMLLAELQHALLA-------- 111 Query: 202 TYPILREDAPLEHVERFFQK-MDRNQD-GVVTIDEFLETCQKDENIMN 247 L E E VE F MD D G + FL + + Sbjct: 112 ----LGESLDDEQVETLFADCMDPEDDEGFIPYSPFLARMCDRPDQLK 155 >1QLS-A nrPDB Length = 99 Score = 35.4 bits (80), Expect = 0.027, Method: Composition-based stats. Identities = 13/62 (20%), Positives = 24/62 (38%), Gaps = 7/62 (11%) Query: 178 KDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLE 237 + I+K E L M + ++ ++R +K+D + DG + EFL Sbjct: 28 NNTKISKTEFLIFMNTELAAFTQNQKDP-------GVLDRMMKKLDLDSDGQLDFQEFLN 80 Query: 238 TC 239 Sbjct: 81 LI 82 Score = 33.1 bits (74), Expect = 0.11, Method: Composition-based stats. Identities = 11/76 (14%), Positives = 28/76 (36%), Gaps = 8/76 (10%) Query: 89 TKKELQSLYRGFKN----ECPTGLVDEDTFKLI----YSQFFPQGDATTYAHFLFNAFDA 140 T++ ++SL F+ + + + F + + F + D Sbjct: 8 TERCIESLIAIFQKHAGRDGNNTKISKTEFLIFMNTELAAFTQNQKDPGVLDRMMKKLDL 67 Query: 141 DGNGAIHFEDFVVGLS 156 D +G + F++F+ + Sbjct: 68 DSDGQLDFQEFLNLIG 83 >5HLO-A nrPDB Length = 94 Score = 35.1 bits (79), Expect = 0.030, Method: Composition-based stats. Identities = 13/61 (21%), Positives = 25/61 (40%), Gaps = 3/61 (4%) Query: 111 EDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVG---LSILLRGTVHEKL 167 D K + PQ A F D + +GA++F++F++ + + HE+ Sbjct: 32 RDDLKKLLETECPQYIRKKGADVWFKELDINTDGAVNFQEFLILVIKMGVAAHKKSHEES 91 Query: 168 K 168 Sbjct: 92 H 92 Score = 29.7 bits (65), Expect = 1.4, Method: Composition-based stats. Identities = 9/27 (33%), Positives = 15/27 (55%) Query: 210 APLEHVERFFQKMDRNQDGVVTIDEFL 236 + + +F+++D N DG V EFL Sbjct: 47 IRKKGADVWFKELDINTDGAVNFQEFL 73 >2WCE-A nrPDB Length = 95 Score = 34.7 bits (78), Expect = 0.036, Method: Composition-based stats. Identities = 11/59 (18%), Positives = 22/59 (37%), Gaps = 7/59 (11%) Query: 181 CITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETC 239 ++K E+ ++ ++ ++ FQ +D NQD V EF+ Sbjct: 30 TLSKGELKQLLTKELANTIKNIKD-------KAVIDEIFQGLDANQDEQVDFQEFISMV 81 Score = 32.7 bits (73), Expect = 0.17, Method: Composition-based stats. Identities = 8/58 (13%), Positives = 23/58 (39%), Gaps = 4/58 (6%) Query: 108 LVDEDTFKLIYSQFFPQG----DATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRG 161 + + K + ++ +F DA+ + + F++F+ ++I L+ Sbjct: 30 TLSKGELKQLLTKELANTIKNIKDKAVIDEIFQGLDANQDEQVDFQEFISMVAIALKA 87 >1KQV-A nrPDB Length = 79 Score = 34.7 bits (78), Expect = 0.042, Method: Composition-based stats. Identities = 9/27 (33%), Positives = 18/27 (66%) Query: 215 VERFFQKMDRNQDGVVTIDEFLETCQK 241 ++ F+++D+N DG V+ +EF +K Sbjct: 50 LDELFEELDKNGDGEVSFEEFQVLVKK 76 Score = 29.7 bits (65), Expect = 1.2, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 31/65 (47%), Gaps = 2/65 (3%) Query: 89 TKKELQSLYRGF--KNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAI 146 + +EL+ ++ + K P L E+ L+ ++F + LF D +G+G + Sbjct: 6 SPEELKGIFEKYAAKEGDPNQLSKEELKLLLQTEFPSLLKGMSTLDELFEELDKNGDGEV 65 Query: 147 HFEDF 151 FE+F Sbjct: 66 SFEEF 70 >2Y5I-A nrPDB Length = 99 Score = 34.3 bits (77), Expect = 0.059, Method: Composition-based stats. Identities = 11/56 (19%), Positives = 22/56 (39%), Gaps = 7/56 (12%) Query: 181 CITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFL 236 ++K E+ ++ + L VE+ +D N+D V +EF+ Sbjct: 28 KLSKGELKELLNA-------ELTDFLMSQKDPMLVEKIMNDLDSNKDNEVDFNEFV 76 Score = 31.6 bits (70), Expect = 0.34, Method: Composition-based stats. Identities = 8/48 (16%), Positives = 19/48 (39%) Query: 111 EDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSIL 158 ++ + F + N D++ + + F +FVV ++ L Sbjct: 35 KELLNAELTDFLMSQKDPMLVEKIMNDLDSNKDNEVDFNEFVVLVAAL 82 >2VTG-A nrPDB Length = 150 Score = 33.5 bits (75), Expect = 0.084, Method: Composition-based stats. Identities = 14/110 (12%), Positives = 38/110 (34%), Gaps = 16/110 (14%) Query: 149 EDFVVGLSILLRGTVHEKL---KWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPI 205 +F+ + EKL K + +D+N +G I + +M+ + Sbjct: 31 REFLCDQKYSDEENLPEKLTAFKEKYMEFDLNNEGEIDLMSLKRMMEKLGVPKTHL---- 86 Query: 206 LREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQ-KDENIMNSMQLFEN 254 +++ ++ ++ +F+ K ++ + +FE Sbjct: 87 --------EMKKMISEVTGGVSDTISYRDFVNMMLGKRSAVLKLVMMFEG 128 >5CSF-A nrPDB Length = 95 Score = 33.5 bits (75), Expect = 0.090, Method: Composition-based stats. Identities = 9/47 (19%), Positives = 19/47 (40%) Query: 193 SIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETC 239 + +++ L E E V++ + +D + DG EF+ Sbjct: 35 ELKELINNELSHFLEEIKEQEVVDKVMETLDNDGDGECDFQEFMAFV 81 Score = 31.6 bits (70), Expect = 0.34, Method: Composition-based stats. Identities = 8/51 (15%), Positives = 20/51 (39%) Query: 111 EDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRG 161 ++ S F + + D DG+G F++F+ ++++ Sbjct: 37 KELINNELSHFLEEIKEQEVVDKVMETLDNDGDGECDFQEFMAFVAMVTTA 87 >4HRG-A nrPDB Length = 115 Score = 33.5 bits (75), Expect = 0.090, Method: Composition-based stats. Identities = 15/75 (20%), Positives = 33/75 (44%), Gaps = 8/75 (10%) Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDR 224 E + + F+ + +K G +TKE++ +M+ + + L V++ + +D+ Sbjct: 11 ETMMFTFHKFAGDK-GYLTKEDLRVLMEKEFPGFLENQKDPLA-------VDKIMKDLDQ 62 Query: 225 NQDGVVTIDEFLETC 239 +DG V F Sbjct: 63 CRDGKVGFQSFFSLI 77 >6AGI-A nrPDB Length = 382 Score = 33.5 bits (75), Expect = 0.092, Method: Composition-based stats. Identities = 24/158 (15%), Positives = 52/158 (32%), Gaps = 28/158 (17%) Query: 36 RFTRQALMRCCLIKWI-LSSAAPQGSDSSDSELEL------STVRHQPEGLDQLQAQTKF 88 RF I+++ S+ S+ + + L +T + + Sbjct: 232 RFMDNLQTEVLEIEFLSYSNGMNTISEEDFAHILLRYTNVENTSVFLENVRYSIPEEKGI 291 Query: 89 TKKELQSLYRGFKNECP------------TGLVDEDTFKLIYSQFFPQGDATTYAHFLFN 136 T E +S ++ F N + + +D FK + + +F Sbjct: 292 TFDEFRSFFQ-FLNNLEDFAIALNMYNFASRSIGQDEFKRAVYVATGLKFSPHLVNTVFK 350 Query: 137 AFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLY 174 FD D + + +++F+ G + ++L F Y Sbjct: 351 IFDVDKDDQLSYKEFI--------GIMKDRLHRGFRGY 380 Score = 33.1 bits (74), Expect = 0.12, Method: Composition-based stats. Identities = 23/133 (17%), Positives = 49/133 (36%), Gaps = 17/133 (12%) Query: 108 LVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKL 167 + E+ F I ++ + + + + + + I F++F S E Sbjct: 255 TISEEDFAHILLRYTNVENTSVFLENVRYSIPEEKG--ITFDEF---RSFFQFLNNLEDF 309 Query: 168 KWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQD 227 A N+Y+ I ++E +++Y G P L V F+ D ++D Sbjct: 310 AIALNMYNF-ASRSIGQDEFK---RAVYVATGLKFSPHL--------VNTVFKIFDVDKD 357 Query: 228 GVVTIDEFLETCQ 240 ++ EF+ + Sbjct: 358 DQLSYKEFIGIMK 370 Score = 31.2 bits (69), Expect = 0.43, Method: Composition-based stats. Identities = 20/106 (18%), Positives = 40/106 (37%), Gaps = 6/106 (5%) Query: 63 SDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFF 122 + ++ + + L+Q+ A+T K L+R K + G++ + Sbjct: 45 DEPKVAKTWKSLSKQELNQMLAETPPVWKGSSKLFRNLKEK---GVISYTEY---LFLLC 98 Query: 123 PQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLK 168 FN FD DGN + ++F+V I + ++K Sbjct: 99 ILTKPHAGFRIAFNMFDTDGNEMVDKKEFLVLQEIFRKKNEKREIK 144 >2MJW-B nrPDB Length = 94 Score = 33.5 bits (75), Expect = 0.094, Method: Composition-based stats. Identities = 12/63 (19%), Positives = 25/63 (39%), Gaps = 4/63 (6%) Query: 103 ECPTGLVDEDTFKLIYSQ----FFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSIL 158 E T + + K++ + F G L DA+G+ + F +F+V ++ + Sbjct: 22 EGSTQTLTKGELKVLMEKELPGFLQSGKDKDAVDKLLKDLDANGDAQVDFSEFIVFVAAI 81 Query: 159 LRG 161 Sbjct: 82 TSA 84 Score = 32.7 bits (73), Expect = 0.15, Method: Composition-based stats. Identities = 9/44 (20%), Positives = 19/44 (43%) Query: 193 SIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFL 236 + +M + L+ + V++ + +D N D V EF+ Sbjct: 32 ELKVLMEKELPGFLQSGKDKDAVDKLLKDLDANGDAQVDFSEFI 75 >4FTG-A nrPDB Length = 96 Score = 33.5 bits (75), Expect = 0.096, Method: Composition-based stats. Identities = 15/75 (20%), Positives = 33/75 (44%), Gaps = 8/75 (10%) Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDR 224 E + + F+ + +K G +TKE++ +M+ + + L V++ + +D+ Sbjct: 9 ETMMFTFHKFAGDK-GYLTKEDLRVLMEKEFPGFLENQKDPLA-------VDKIMKDLDQ 60 Query: 225 NQDGVVTIDEFLETC 239 +DG V F Sbjct: 61 CRDGKVGFQSFFSLI 75 >3H4S-E nrPDB Length = 135 Score = 32.4 bits (72), Expect = 0.18, Method: Composition-based stats. Identities = 18/116 (15%), Positives = 43/116 (37%), Gaps = 2/116 (1%) Query: 57 PQGSDSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGF--KNECPTGLVDEDTF 114 P + + + E + + A+ ++ + L +GF + L+ ++ Sbjct: 3 PTEKSMLLETTSTTKMETKYEDMLPVMAEKMDVEEFVSELCKGFSLLADPERHLITAESL 62 Query: 115 KLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWA 170 + +G + A + D DG+GA++ +F V + L + + W Sbjct: 63 RRNSGILGIEGMSKEDAQGMVREGDLDGDGALNQTEFCVLMVRLSPEMMEDAETWL 118 Score = 29.7 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 9/49 (18%), Positives = 20/49 (40%), Gaps = 1/49 (2%) Query: 200 RHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEF-LETCQKDENIMN 247 R++ + E E + ++ D + DG + EF + + +M Sbjct: 64 RNSGILGIEGMSKEDAQGMVREGDLDGDGALNQTEFCVLMVRLSPEMME 112 >4AOM-A nrPDB Length = 146 Score = 32.4 bits (72), Expect = 0.20, Method: Composition-based stats. Identities = 21/119 (17%), Positives = 45/119 (37%), Gaps = 7/119 (5%) Query: 100 FKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILL 159 F + G + D Y+ ++ D + +E ++ LSI + Sbjct: 23 FNEKSSGGKISIDN--ASYNARKLGLAPSSIDEKKIKELYGDN---LTYEQYLEYLSICV 77 Query: 160 RGTVH-EKLKWAFNLYDINKDGCITKEEMLAIMKSIYD-MMGRHTYPILREDAPLEHVE 216 + E+L F +D N G +TK +M I+ + D + + L + ++++ Sbjct: 78 HDKDNVEELIKMFAHFDNNCTGYLTKSQMKNILTTWGDALTDQEAIDALNAFSSEDNID 136 >2MHH-A nrPDB Length = 96 Score = 32.4 bits (72), Expect = 0.20, Method: Composition-based stats. Identities = 12/52 (23%), Positives = 25/52 (48%), Gaps = 2/52 (3%) Query: 139 DADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAI 190 DA+ + + F+++ L RG ++ F YD++ D + EE + + Sbjct: 28 DANADQHLDFDEWRQEL--KCRGHADADIEAVFAKYDVDGDRVLDAEEQMKM 77 >2JXC-A nrPDB Length = 100 Score = 32.4 bits (72), Expect = 0.22, Method: Composition-based stats. Identities = 9/30 (30%), Positives = 17/30 (56%) Query: 206 LREDAPLEHVERFFQKMDRNQDGVVTIDEF 235 L P++ + R ++ D + DG++ DEF Sbjct: 41 LNSKLPVDILGRVWELSDIDHDGMLDRDEF 70 >5LXV-B nrPDB Length = 88 Score = 32.0 bits (71), Expect = 0.30, Method: Composition-based stats. Identities = 12/50 (24%), Positives = 21/50 (42%), Gaps = 5/50 (10%) Query: 139 DADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEML 188 D DG+G + D ++ + G F D+N DG I +++ Sbjct: 27 DLDGDGEVDVFDLILMRKAVENGDTER-----FEAADLNCDGVIDSDDLT 71 Score = 27.0 bits (58), Expect = 9.0, Method: Composition-based stats. Identities = 16/73 (21%), Positives = 30/73 (41%), Gaps = 23/73 (31%) Query: 175 DINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTID- 233 D++ DG + +++ + K++ E+ E F+ D N DGV+ D Sbjct: 27 DLDGDGEVDVFDLILMRKAV-------------ENGDTER----FEAADLNCDGVIDSDD 69 Query: 234 -----EFLETCQK 241 E+L +K Sbjct: 70 LTYHSEYLHGIRK 82 >2AUC-A nrPDB Length = 126 Score = 32.0 bits (71), Expect = 0.30, Method: Composition-based stats. Identities = 13/60 (21%), Positives = 30/60 (50%), Gaps = 1/60 (1%) Query: 144 GAIHFEDFVVGLSILLRGTVH-EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHT 202 ++ +E ++ L++ + + E+L F+ +D N G +TK +M I+ + D + Sbjct: 43 DSLTYEQYLEYLTMCVHDRDNMEELIKMFSHFDNNSSGFLTKNQMKNILTTWGDALTEQE 102 >1FI6-A nrPDB Length = 92 Score = 31.6 bits (70), Expect = 0.33, Method: Composition-based stats. Identities = 11/66 (16%), Positives = 22/66 (33%), Gaps = 14/66 (21%) Query: 171 FNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVV 230 F + +G I + P+ + ++ D ++DG + Sbjct: 15 FKTIQPDLNGFIPGSAAKEFF--------------TKSKLPILELSHIWELSDFDKDGAL 60 Query: 231 TIDEFL 236 T+DEF Sbjct: 61 TLDEFC 66 >5MKE-A nrPDB Length = 968 Score = 31.6 bits (70), Expect = 0.33, Method: Composition-based stats. Identities = 11/49 (22%), Positives = 23/49 (46%), Gaps = 2/49 (4%) Query: 142 GNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAI 190 G G ++F++ L +G +++ F YD + D +T+ E + Sbjct: 732 GGGKLNFDELRQDL--KGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQM 778 Score = 28.1 bits (61), Expect = 3.3, Method: Composition-based stats. Identities = 10/61 (16%), Positives = 19/61 (31%), Gaps = 14/61 (22%) Query: 178 KDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLE 237 G + +E+ +K +E F K D++ D +T E + Sbjct: 732 GGGKLNFDELRQDLKGKGH--------------TDAEIEAIFTKYDQDGDQELTEHEHQQ 777 Query: 238 T 238 Sbjct: 778 M 778 >6D1W-A nrPDB Length = 740 Score = 31.6 bits (70), Expect = 0.36, Method: Composition-based stats. Identities = 11/49 (22%), Positives = 23/49 (46%), Gaps = 2/49 (4%) Query: 142 GNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAI 190 G G ++F++ L +G +++ F YD + D +T+ E + Sbjct: 680 GGGKLNFDELRQDL--KGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQM 726 Score = 28.1 bits (61), Expect = 3.6, Method: Composition-based stats. Identities = 10/61 (16%), Positives = 19/61 (31%), Gaps = 14/61 (22%) Query: 178 KDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLE 237 G + +E+ +K +E F K D++ D +T E + Sbjct: 680 GGGKLNFDELRQDLKGKGH--------------TDAEIEAIFTKYDQDGDQELTEHEHQQ 725 Query: 238 T 238 Sbjct: 726 M 726 >2JQ6-A nrPDB Length = 139 Score = 31.2 bits (69), Expect = 0.50, Method: Composition-based stats. Identities = 6/33 (18%), Positives = 18/33 (54%) Query: 203 YPILREDAPLEHVERFFQKMDRNQDGVVTIDEF 235 +++ P + + ++ D ++DG++ +EF Sbjct: 74 KEMVKSKLPNTVLGKIWKLADVDKDGLLDDEEF 106 >3FSR-A nrPDB Length = 352 Score = 30.8 bits (68), Expect = 0.58, Method: Composition-based stats. Identities = 10/37 (27%), Positives = 17/37 (45%), Gaps = 2/37 (5%) Query: 103 ECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFD 139 CP G + + +LI F+ + D + +F FD Sbjct: 294 LCPGGRLRME--RLIDLVFYKRVDPSKLVTHVFRGFD 328 >3FPC-A nrPDB Length = 352 Score = 30.8 bits (68), Expect = 0.58, Method: Composition-based stats. Identities = 10/37 (27%), Positives = 17/37 (45%), Gaps = 2/37 (5%) Query: 103 ECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFD 139 CP G + + +LI F+ + D + +F FD Sbjct: 294 LCPGGRLRME--RLIDLVFYKRVDPSKLVTHVFRGFD 328 >1YKF-A nrPDB Length = 352 Score = 30.8 bits (68), Expect = 0.58, Method: Composition-based stats. Identities = 10/37 (27%), Positives = 17/37 (45%), Gaps = 2/37 (5%) Query: 103 ECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFD 139 CP G + + +LI F+ + D + +F FD Sbjct: 294 LCPGGRLRME--RLIDLVFYKRVDPSKLVTHVFRGFD 328 >6DU8-A nrPDB Length = 805 Score = 30.8 bits (68), Expect = 0.67, Method: Composition-based stats. Identities = 21/119 (17%), Positives = 41/119 (34%), Gaps = 9/119 (7%) Query: 142 GNGAIHFEDFVVGLSILLRGTVHE-KLKWAFNLYDINKDGCITKEE---MLAIMKSIYDM 197 G I FEDF L L +L F +D + + + ++E M ++ Sbjct: 612 GEQEIQFEDFTNTLRELGHAEHEITELTATFTKFDRDGNRILDEKEQEKMRQDLEEERVA 671 Query: 198 MGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQLFENVI 256 + L + + R G V+ +EF ++ ++ + E V+ Sbjct: 672 LNTEIEK-LGRSIVSSPQGKSGPEAARAG-GWVSGEEFYMLTRR---VLQLETVLEGVV 725 >3DFA-A nrPDB Length = 286 Score = 30.4 bits (67), Expect = 0.68, Method: Composition-based stats. Identities = 6/19 (31%), Positives = 7/19 (36%), Gaps = 2/19 (10%) Query: 39 RQALMRCCLIKWI--LSSA 55 R +C WI SS Sbjct: 268 RITATQCLEHPWIQKYSSE 286 >3RNC-B nrPDB Length = 330 Score = 30.4 bits (67), Expect = 0.70, Method: Composition-based stats. Identities = 19/124 (15%), Positives = 45/124 (36%), Gaps = 17/124 (13%) Query: 52 LSSAAPQGSDSSDSELELSTVRHQPEGLDQLQAQTKF------------TKKELQSLYRG 99 +S P+ + L+ R +P + + + + +Q+ Y+ Sbjct: 1 MSEQQPEALKPLKTWSHLAGNRRRPSEYEVVSTNLHYFTDNPERPWELDSNLPMQTWYKK 60 Query: 100 FKNECPTGLVDEDTF----KLIYSQFFPQGD-ATTYAHFLFNAFDADGNGAIHFEDFVVG 154 + + P D + F +L+Y + D +Y LF+ + G+ + ++V Sbjct: 61 YCFDSPLKHDDWNAFRDPDQLVYRTYNLLQDGQESYVQGLFDQLNDRGHDQMLTREWVET 120 Query: 155 LSIL 158 L+ Sbjct: 121 LARF 124 >2KFH-A nrPDB Length = 105 Score = 30.4 bits (67), Expect = 0.71, Method: Composition-based stats. Identities = 6/33 (18%), Positives = 18/33 (54%) Query: 203 YPILREDAPLEHVERFFQKMDRNQDGVVTIDEF 235 +++ P + + ++ D ++DG++ +EF Sbjct: 40 KEMVKSKLPNTVLGKIWKLADVDKDGLLDDEEF 72 >2Y3N-B nrPDB Length = 71 Score = 30.4 bits (67), Expect = 0.76, Method: Composition-based stats. Identities = 14/60 (23%), Positives = 24/60 (40%), Gaps = 15/60 (25%) Query: 175 DINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDE 234 D+N DG I +++ + +S +G +K D N DGV+ D+ Sbjct: 8 DLNGDGVINMADVMILAQSFGKAIGNPGVN---------------EKADLNNDGVINSDD 52 >4OUN-A nrPDB Length = 163 Score = 30.4 bits (67), Expect = 0.79, Method: Composition-based stats. Identities = 19/95 (20%), Positives = 35/95 (36%), Gaps = 12/95 (12%) Query: 60 SDSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDT------ 113 +D + + + Q E L LQ Q+ FT++E L RG +G ++T Sbjct: 63 NDLHKKSSRIVSAKSQAEILFFLQNQSFFTEEEEAVLKRG--RNAKSGTTPKNTDVQTYR 120 Query: 114 ----FKLIYSQFFPQGDATTYAHFLFNAFDADGNG 144 F+ + F + + + A +G Sbjct: 121 YSTAFQALLGYLFLEKKEERLSQLVAEAIQFGTSG 155 >6J79-A nrPDB Length = 871 Score = 30.0 bits (66), Expect = 1.00, Method: Composition-based stats. Identities = 13/64 (20%), Positives = 24/64 (37%), Gaps = 6/64 (9%) Query: 56 APQGSDSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFK 115 P+GS +L+ S + E L + + + + F G V + FK Sbjct: 15 VPRGSHMERPQLD-SMSQDLSEALKEATKEVHIRAENSE-----FMRNFQKGQVSREGFK 68 Query: 116 LIYS 119 L+ + Sbjct: 69 LVMA 72 >6QAA-A nrPDB Length = 557 Score = 30.0 bits (66), Expect = 1.0, Method: Composition-based stats. Identities = 16/67 (23%), Positives = 23/67 (34%), Gaps = 1/67 (1%) Query: 99 GFKNECPTGLVDEDTFKLIYSQFFPQGDA-TTYAHFLFNAFDADGNGAIHFEDFVVGLSI 157 F + P L++ FK D T + + F D N I ++F GL I Sbjct: 325 DFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKI 384 Query: 158 LLRGTVH 164 G Sbjct: 385 FFPGVSE 391 >1WY9-A nrPDB Length = 147 Score = 30.0 bits (66), Expect = 1.0, Method: Composition-based stats. Identities = 12/90 (13%), Positives = 33/90 (36%), Gaps = 17/90 (18%) Query: 169 WAFNL----YDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDR 224 AF + +D+N +G I + +++ + ++R +++ Sbjct: 48 EAFKVKYMEFDLNGNGDIDIMSLKRMLEKLGVPKTHL------------ELKRLIREVSS 95 Query: 225 NQDGVVTIDEFLETCQ-KDENIMNSMQLFE 253 + + +FL K I+ + ++E Sbjct: 96 GSEETFSYSDFLRMMLGKRSAILRMILMYE 125 >4C0K-A nrPDB Length = 423 Score = 30.0 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 24/159 (15%), Positives = 52/159 (32%), Gaps = 12/159 (7%) Query: 81 QLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFD- 139 + Q T KK L +++ + L+++ L + F + Sbjct: 3 EEQELTSACKKSLVRIFK-ICDIDGDNLLNDYELNLFQRRCFNTPLQPQILDEVKAVIQK 61 Query: 140 --ADG--NGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIY 195 DG N A+ + F+ + ++ +E + G + EM Sbjct: 62 NVPDGIYNDAVTLKGFLFLHCLFIQRGRNETTWAVLRRF-----GYNDQLEMCQEYLRPP 116 Query: 196 DMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDE 234 + + L + F++ DR+ DG ++ +E Sbjct: 117 LKIPPGSSTELSHRGQQFLI-AVFERYDRDGDGALSPEE 154 >1ZQ1-C nrPDB Length = 633 Score = 30.0 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 24/64 (37%), Gaps = 7/64 (10%) Query: 163 VHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILRED----APLEHVERF 218 E ++ AF LY +G I KE I K + + + E E V R Sbjct: 523 TDEHIREAFQLY---LEGKIAKEAFEEIFKELARNPSKSAREVAEEKGLTLLSEEEVTRI 579 Query: 219 FQKM 222 +++ Sbjct: 580 IEEV 583 >4YBH-B nrPDB Length = 92 Score = 30.0 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 9/56 (16%), Positives = 23/56 (41%), Gaps = 9/56 (16%) Query: 181 CITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFL 236 ++K+E+ +++ + + R + +DRN+D V E++ Sbjct: 30 TLSKKELKELIQK---------ELTIGSKLQDAEIARLMEDLDRNKDQEVNFQEYV 76 >2KHN-A nrPDB Length = 121 Score = 29.3 bits (64), Expect = 1.6, Method: Composition-based stats. Identities = 9/42 (21%), Positives = 16/42 (38%) Query: 210 APLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQL 251 P + + + D N DG + EF + + + QL Sbjct: 63 LPQPVLAQIWALADMNNDGRMDQVEFSIAMKLIKLKLQGYQL 104 >4PCW-A nrPDB Length = 94 Score = 29.3 bits (64), Expect = 1.7, Method: Composition-based stats. Identities = 8/38 (21%), Positives = 14/38 (36%) Query: 118 YSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGL 155 + Q D + D D N I F +F++ + Sbjct: 43 FRQILKNPDDPDMVDVFMDHLDIDHNKKIDFTEFLLMV 80 Score = 27.0 bits (58), Expect = 7.4, Method: Composition-based stats. Identities = 7/29 (24%), Positives = 13/29 (44%) Query: 213 EHVERFFQKMDRNQDGVVTIDEFLETCQK 241 + V+ F +D + + + EFL K Sbjct: 54 DMVDVFMDHLDIDHNKKIDFTEFLLMVFK 82 >5X2E-A nrPDB Length = 80 Score = 29.3 bits (64), Expect = 1.7, Method: Composition-based stats. Identities = 15/53 (28%), Positives = 25/53 (47%), Gaps = 4/53 (7%) Query: 134 LFNAFDADGNGAIHFEDFVVGLSI-LLRGTVHEKLKWAFNLYDINKDGCITKE 185 +F + D DG I + + ++ L ++ EK K L+D + G IT E Sbjct: 6 IFVSIDKDGTNVISYPELEQYVAENNLDPSMVEKWK---QLFDPDNTGSITLE 55 >2L5Y-A nrPDB Length = 150 Score = 29.3 bits (64), Expect = 1.8, Method: Composition-based stats. Identities = 11/44 (25%), Positives = 23/44 (52%) Query: 199 GRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKD 242 G H + LE ++ ++MD ++DG + ++E E ++D Sbjct: 1 GSHMASTEEDRFSLEALQTIHKQMDDDKDGGIEVEESDEFIRED 44 >5MVF-A nrPDB Length = 523 Score = 28.9 bits (63), Expect = 2.1, Method: Composition-based stats. Identities = 8/53 (15%), Positives = 22/53 (41%), Gaps = 2/53 (3%) Query: 185 EEMLAIMKSIYDMMG--RHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEF 235 +E+ + I + ++ P + + ++ D + DG++ +EF Sbjct: 434 DELFYTLSPINGKISGVNAKKEMVTSKLPNSVLGKIWKLADCDCDGMLDEEEF 486 >4WR2-A nrPDB Length = 335 Score = 28.9 bits (63), Expect = 2.5, Method: Composition-based stats. Identities = 7/34 (20%), Positives = 19/34 (55%) Query: 150 DFVVGLSILLRGTVHEKLKWAFNLYDINKDGCIT 183 ++ G++++ R + K A L+D+++ G + Sbjct: 292 EYTQGMTVVDRYQLTGKTANATVLFDLDRQGFVD 325 >2V9K-A nrPDB Length = 530 Score = 28.5 bits (62), Expect = 2.6, Method: Composition-based stats. Identities = 9/61 (14%), Positives = 25/61 (40%) Query: 185 EEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDEN 244 E+ +++ D + + L+ +E + +N +G +++ T K+ N Sbjct: 47 NELQKFLETEKDELILEVMNPPPKKIRLQELEDSIDNLSQNGEGRISVSHVGSTASKNSN 106 Query: 245 I 245 + Sbjct: 107 L 107 >2QPT-A nrPDB Length = 550 Score = 28.5 bits (62), Expect = 2.7, Method: Composition-based stats. Identities = 7/31 (22%), Positives = 17/31 (54%) Query: 205 ILREDAPLEHVERFFQKMDRNQDGVVTIDEF 235 ++ P + R ++ D ++DG++ +EF Sbjct: 483 MVGTKLPNSVLGRIWKLSDVDRDGMLDDEEF 513 >6HIV-CJ nrPDB Length = 817 Score = 28.1 bits (61), Expect = 3.8, Method: Composition-based stats. Identities = 9/40 (22%), Positives = 14/40 (35%), Gaps = 1/40 (2%) Query: 127 ATTYAHFLFNAFDADGNGAIHF-EDFVVGLSILLRGTVHE 165 + FN FDA G + + +F RG + Sbjct: 96 PNAFRFRPFNEFDAKGREYVQYMREFARFDPRKSRGNGQK 135 >2JTT-A nrPDB Length = 90 Score = 28.1 bits (61), Expect = 3.9, Method: Composition-based stats. Identities = 8/56 (14%), Positives = 22/56 (39%), Gaps = 9/56 (16%) Query: 181 CITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFL 236 ++K+E+ +++ + + + +DRN+D V E++ Sbjct: 28 TLSKKELKELIQK---------ELTIGSKLQDAEIVKLMDDLDRNKDQEVNFQEYI 74 >1DJX-A nrPDB Length = 624 Score = 28.1 bits (61), Expect = 4.1, Method: Composition-based stats. Identities = 14/98 (14%), Positives = 34/98 (34%), Gaps = 15/98 (15%) Query: 156 SILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHV 215 S+ R + + D NKD + +E+ +K + + + Sbjct: 2 SMDQRQKLQHWIHSCLRKADKNKDNKMNFKELKDFLKELNIQVD------------DGYA 49 Query: 216 ERFFQKMDRNQDGVVTIDE---FLETCQKDENIMNSMQ 250 + F++ D +Q + +E F + + I + + Sbjct: 50 RKIFRECDHSQTDSLEDEEIETFYKMLTQRAEIDRAFE 87 >4DUQ-A nrPDB Length = 98 Score = 27.7 bits (60), Expect = 4.5, Method: Composition-based stats. Identities = 10/55 (18%), Positives = 21/55 (38%), Gaps = 7/55 (12%) Query: 181 CITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEF 235 ++K EM ++ + + E E +++ +D N D V E+ Sbjct: 29 KLSKGEMKELLH-------KELPSFVGEKVDEEGLKKLMGSLDENSDQQVDFQEY 76 >3X0D-A nrPDB Length = 655 Score = 27.7 bits (60), Expect = 4.8, Method: Composition-based stats. Identities = 13/47 (27%), Positives = 17/47 (36%), Gaps = 1/47 (2%) Query: 138 FDADGNGAIHFED-FVVGLSILLRGTVHEKLKWAFNLYDINKDGCIT 183 FD + I F++ FV GT+ L W D N I Sbjct: 246 FDFEHEEKIIFDESFVREAVAHSSGTIDALLMWWDIDMDRNGTTFID 292 >3NSO-A nrPDB Length = 101 Score = 27.7 bits (60), Expect = 5.2, Method: Composition-based stats. Identities = 8/53 (15%), Positives = 20/53 (37%), Gaps = 4/53 (7%) Query: 108 LVDEDTFKLIYSQFFPQGDATTYAHFLFNAF----DADGNGAIHFEDFVVGLS 156 + + K + + T + +N F D + + + F ++V L+ Sbjct: 28 KLCQAELKELLQKELATWTPTEFRECDYNKFMSVLDTNKDCEVDFVEYVRSLA 80 Score = 27.0 bits (58), Expect = 7.6, Method: Composition-based stats. Identities = 7/59 (11%), Positives = 21/59 (35%), Gaps = 7/59 (11%) Query: 181 CITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETC 239 + + E+ +++ + + +F +D N+D V E++ + Sbjct: 28 KLCQAELKELLQ-------KELATWTPTEFRECDYNKFMSVLDTNKDCEVDFVEYVRSL 79 >3QR0-A nrPDB Length = 816 Score = 27.7 bits (60), Expect = 5.6, Method: Composition-based stats. Identities = 8/39 (20%), Positives = 21/39 (53%), Gaps = 4/39 (10%) Query: 214 HVERFFQKMDRNQDGVVT---IDEFLETCQKDENIMNSM 249 +E F+++ +N+ G +T +FL Q+ ++ ++ Sbjct: 230 EIEGIFKELSKNK-GNITTVMFRDFLNDMQRHPSLHKTL 267 >6F8L-G nrPDB Length = 913 Score = 27.3 bits (59), Expect = 6.4, Method: Composition-based stats. Identities = 17/93 (18%), Positives = 26/93 (27%), Gaps = 11/93 (11%) Query: 55 AAPQGSDSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECP--------- 105 A P G + + E+ LS RH+ L +F Q+ F+ P Sbjct: 250 AVPIGFQNGEVEVVLSDPRHKEAVAQLLNRPARFYLALPQAWEELFRRAYPQKNRLGEVL 309 Query: 106 --TGLVDEDTFKLIYSQFFPQGDATTYAHFLFN 136 G + + K A L Sbjct: 310 VQEGKLSREALKEALEVQKGLPRAKPLGEILVE 342 >1C07-A nrPDB Length = 95 Score = 27.3 bits (59), Expect = 6.6, Method: Composition-based stats. Identities = 11/61 (18%), Positives = 21/61 (34%), Gaps = 14/61 (22%) Query: 175 DINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDE 234 D + DG ++ E+ I L+ P + + D G ++ D+ Sbjct: 20 DKDMDGFVSGLEVREIF--------------LKTGLPSTLLAHIWSLCDTKDCGKLSKDQ 65 Query: 235 F 235 F Sbjct: 66 F 66 >4GFT-A nrPDB Length = 69 Score = 27.3 bits (59), Expect = 7.0, Method: Composition-based stats. Identities = 11/38 (28%), Positives = 18/38 (47%) Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHT 202 E+L F +D N G +TK +M I+ + D + Sbjct: 7 EELIKMFAHFDNNSTGYLTKSQMKNILTTWGDALTDQE 44 >2GS4-A nrPDB Length = 166 Score = 27.3 bits (59), Expect = 7.3, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 31/73 (42%), Gaps = 3/73 (4%) Query: 153 VGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPL 212 L+ L R T +EKL AF+ + G I + + +++S ++ + + E Sbjct: 26 RALAKLARATSNEKLSQAFHAHLEETHGQIER--IDQVVESESNLKIKRMKCVAMEGLIE 83 Query: 213 EHVERFFQKMDRN 225 E + ++N Sbjct: 84 E-ANEVIESTEKN 95 >1YX2-A nrPDB Length = 365 Score = 27.0 bits (58), Expect = 7.7, Method: Composition-based stats. Identities = 11/50 (22%), Positives = 22/50 (44%) Query: 134 LFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCIT 183 LF+ + G I F + + + HE ++ A L+D++ G + Sbjct: 10 LFDLYKEYGGKTIDFGGWELPVQFSSIKKEHEAVRTAAGLFDVSHMGEVE 59 >5COV-A nrPDB Length = 340 Score = 27.0 bits (58), Expect = 8.5, Method: Composition-based stats. Identities = 18/64 (28%), Positives = 31/64 (48%), Gaps = 5/64 (7%) Query: 165 EKLK----WAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHV-ERFF 219 EKLK + F++YDI+K +T E +++K + D + + +D L H E+ Sbjct: 239 EKLKGQDFYLFDIYDIDKAQYLTPIERQSLVKQLNDNGFTVKHVPILDDLELNHTAEQIL 298 Query: 220 QKMD 223 D Sbjct: 299 AMAD 302 >2G2B-A nrPDB Length = 150 Score = 27.0 bits (58), Expect = 8.6, Method: Composition-based stats. Identities = 11/90 (12%), Positives = 31/90 (34%), Gaps = 13/90 (14%) Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDR 224 E K + +D+N +G I + +++ + +++ ++ Sbjct: 51 EGFKEKYMEFDLNGNGDIDIMSLKRMLEKLGVPKTHL------------ELKKLIGEVSS 98 Query: 225 NQDGVVTIDEFLETCQ-KDENIMNSMQLFE 253 + +FL K I+ + ++E Sbjct: 99 GSGETFSYPDFLRMMLGKRSAILKMILMYE 128 >1XOC-A nrPDB Length = 520 Score = 27.0 bits (58), Expect = 8.7, Method: Composition-based stats. Identities = 10/61 (16%), Positives = 23/61 (37%), Gaps = 8/61 (13%) Query: 176 INKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKM---DRNQDGVVTI 232 ++ DG E+ I +S + + + + ++ + D N DG++ Sbjct: 301 LDGDG-----EVAYIPESPLSWNYPKDIDVPKFEYNEKKAKQMLAEAGWKDTNGDGILDK 355 Query: 233 D 233 D Sbjct: 356 D 356 >5VP3-A nrPDB Length = 206 Score = 27.0 bits (58), Expect = 8.9, Method: Composition-based stats. Identities = 8/43 (18%), Positives = 22/43 (51%) Query: 165 EKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILR 207 E+L F+ +D++ DG +T +E++ + ++ + + Sbjct: 34 ERLYKRFDTFDLDTDGKMTMDEIMYWPDRMRQLVNATDEQVEK 76 >5LPU-C nrPDB Length = 104 Score = 27.0 bits (58), Expect = 9.0, Method: Composition-based stats. Identities = 9/54 (16%), Positives = 25/54 (46%), Gaps = 6/54 (11%) Query: 108 LVDEDTFKLIYSQFFP-----QGDATTYAHFLFNAFDADGNGAIHFEDFVVGLS 156 +++ K + ++ P + D + L + D++ + + F+++ V LS Sbjct: 31 KLNKSELKELLTRELPSFLGKRTDEAAF-QKLMSNLDSNRDNEVDFQEYCVFLS 83 Score = 27.0 bits (58), Expect = 9.6, Method: Composition-based stats. Identities = 9/56 (16%), Positives = 19/56 (33%), Gaps = 7/56 (12%) Query: 181 CITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFL 236 + K E+ ++ R L + ++ +D N+D V E+ Sbjct: 31 KLNKSELKELLT-------RELPSFLGKRTDEAAFQKLMSNLDSNRDNEVDFQEYC 79 >2KLD-A nrPDB Length = 123 Score = 27.0 bits (58), Expect = 9.2, Method: Composition-based stats. Identities = 11/49 (22%), Positives = 23/49 (46%), Gaps = 2/49 (4%) Query: 142 GNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAI 190 G G ++F++ L +G +++ F YD + D +T+ E + Sbjct: 59 GGGKLNFDELRQDL--KGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQM 105 >5NRK-B nrPDB Length = 68 Score = 26.6 bits (57), Expect = 9.9, Method: Composition-based stats. Identities = 15/62 (24%), Positives = 26/62 (41%) Query: 139 DADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMM 198 D DGNG+I+ DF + + LL + D+N D I + + + M+ Sbjct: 4 DVDGNGSININDFALMRNYLLGNLKDFPAEDDIKAGDLNGDKSINSLDFAIMRMYLLGMI 63 Query: 199 GR 200 + Sbjct: 64 TK 65 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.313 0.133 0.365 Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,179,409 Number of Sequences: 36641 Number of extensions: 403325 Number of successful extensions: 3915 Number of sequences better than 10.0: 342 Number of HSP's better than 10.0 without gapping: 395 Number of HSP's successfully gapped in prelim test: 121 Number of HSP's that attempted gapping in prelim test: 1664 Number of HSP's gapped (non-prelim): 1234 length of query: 256 length of database: 10,336,785 effective HSP length: 95 effective length of query: 161 effective length of database: 6,855,890 effective search space: 1103798290 effective search space used: 1103798290 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 58 (27.0 bits)