BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9P2T1 (348 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2C6Q-A nrPDB 685 0.0 2BWG-A nrPDB 592 e-170 3R2G-A nrPDB 207 7e-54 5UQG-A nrPDB 194 5e-50 4MJM-A nrPDB 193 1e-49 1VRD-A nrPDB 186 2e-47 4QJ1-A nrPDB 177 7e-45 1YPF-A nrPDB 177 8e-45 4FEZ-A nrPDB 176 2e-44 1EEP-A nrPDB 175 3e-44 3TSB-A nrPDB 172 2e-43 3FFS-A nrPDB 171 4e-43 1ZFJ-A nrPDB 171 6e-43 4FXS-A nrPDB 155 3e-38 5UPU-A nrPDB 152 2e-37 5AHL-A nrPDB 150 6e-37 2CU0-A nrPDB 146 1e-35 4XTI-A nrPDB 139 2e-33 4DQW-A nrPDB 138 4e-33 4Z87-A nrPDB 130 8e-31 4AF0-B nrPDB 125 2e-29 6I0M-A nrPDB 121 4e-28 1JCN-A nrPDB 118 4e-27 1AK5-A nrPDB 78 5e-15 5FIR-A nrPDB 32 0.39 4V4P-AP nrPDB 30 1.2 6HIS-A nrPDB 29 3.1 1SVD-A nrPDB 28 5.1 >2C6Q-A nrPDB Length = 351 Score = 685 bits (1767), Expect = 0.0, Method: Compositional matrix adjust. Identities = 332/332 (100%), Positives = 332/332 (100%) Query: 10 LDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFEMAKVLCK 69 LDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFEMAKVLCK Sbjct: 20 LDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFEMAKVLCK 79 Query: 70 FSLFTAVHKHYSLVQWQEFAGQNPDCLEHLAASSGTGSSDFEQLEQILEAIPQVKYICLD 129 FSLFTAVHKHYSLVQWQEFAGQNPDCLEHLAASSGTGSSDFEQLEQILEAIPQVKYICLD Sbjct: 80 FSLFTAVHKHYSLVQWQEFAGQNPDCLEHLAASSGTGSSDFEQLEQILEAIPQVKYICLD 139 Query: 130 VANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTTR 189 VANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTTR Sbjct: 140 VANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTTR 199 Query: 190 KKTGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHS 249 KKTGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHS Sbjct: 200 KKTGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHS 259 Query: 250 ESGGELIERDGKKYKLFYGMSSEMAMKKYAGGVAEYRASEGKTVEVPFKGDVEHTIRDIL 309 ESGGELIERDGKKYKLFYGMSSEMAMKKYAGGVAEYRASEGKTVEVPFKGDVEHTIRDIL Sbjct: 260 ESGGELIERDGKKYKLFYGMSSEMAMKKYAGGVAEYRASEGKTVEVPFKGDVEHTIRDIL 319 Query: 310 GGIRSTCTYVGAAKLKELSRRTTFIRVTQQVN 341 GGIRSTCTYVGAAKLKELSRRTTFIRVTQQVN Sbjct: 320 GGIRSTCTYVGAAKLKELSRRTTFIRVTQQVN 351 >2BWG-A nrPDB Length = 367 Score = 592 bits (1527), Expect = e-170, Method: Compositional matrix adjust. Identities = 276/345 (80%), Positives = 315/345 (91%) Query: 1 MPHIDNDVKLDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGT 60 MP ID D+KLDFKDVLLRPKRS+LKSR+EVDL R+F+FRNSKQTYSG+PII ANMDTVGT Sbjct: 23 MPRIDADLKLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGT 82 Query: 61 FEMAKVLCKFSLFTAVHKHYSLVQWQEFAGQNPDCLEHLAASSGTGSSDFEQLEQILEAI 120 FEMA V+ + S+FTA+HKHYSL W+ FA +P+CL+++A SSG+G +D E++ ILEA+ Sbjct: 83 FEMAAVMSQHSMFTAIHKHYSLDDWKLFATNHPECLQNVAVSSGSGQNDLEKMTSILEAV 142 Query: 121 PQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGI 180 PQVK+ICLDVANGYSEHFVEFVK VR +FP+HTIMAGNVVTGEMVEELILSGADIIKVG+ Sbjct: 143 PQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGV 202 Query: 181 GPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVM 240 GPGSVCTTR KTGVGYPQLSAV+ECAD+AHGLKGHIISDGGC+CPGDVAKAFGAGADFVM Sbjct: 203 GPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVM 262 Query: 241 LGGMLAGHSESGGELIERDGKKYKLFYGMSSEMAMKKYAGGVAEYRASEGKTVEVPFKGD 300 LGGM +GH+E GE+IER+G+K KLFYGMSS+ AM K+AGGVAEYRASEGKTVEVP+KGD Sbjct: 263 LGGMFSGHTECAGEVIERNGRKLKLFYGMSSDTAMNKHAGGVAEYRASEGKTVEVPYKGD 322 Query: 301 VEHTIRDILGGIRSTCTYVGAAKLKELSRRTTFIRVTQQVNPIFS 345 VE+TI DILGG+RSTCTYVGAAKLKELSRR TFIRVTQQ N +FS Sbjct: 323 VENTILDILGGLRSTCTYVGAAKLKELSRRATFIRVTQQHNTVFS 367 >3R2G-A nrPDB Length = 361 Score = 207 bits (526), Expect = 7e-54, Method: Compositional matrix adjust. Identities = 126/335 (37%), Positives = 191/335 (57%), Gaps = 15/335 (4%) Query: 6 NDVKLDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFEMAK 65 D + F DVLL P + +SR V+ T + R K T + +P+I+ANMDT+ MA Sbjct: 4 TDQAITFDDVLLVPSYNHHESRRVVETTSTD--RLGKLTLN-LPVISANMDTITESNMAN 60 Query: 66 VLCKFSLFTAVHKHYSLVQ-WQEFAGQNPDCLEHLAASSGTGSSDFEQLEQILEAIPQVK 124 + A+H+ ++ + QEF C + S G ++ ++ E + +A Sbjct: 61 FMHSKGAMGALHRFMTIEENIQEF----KKCKGPVFVSVGCTENELQRAEALRDA--GAD 114 Query: 125 YICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGS 184 + C+DVA+ ++++ + +K +R+ IMAGNV T + L GADIIK GIG GS Sbjct: 115 FFCVDVAHAHAKYVGKTLKSLRQLLGSRCIMAGNVATYAGADYLASCGADIIKAGIGGGS 174 Query: 185 VCTTRKKTGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGM 244 VC+TR KTG G P L+ + +C+ A I++DGG GD+ KA GADFVM+GGM Sbjct: 175 VCSTRIKTGFGVPMLTCIQDCSRADR----SIVADGGIKTSGDIVKALAFGADFVMIGGM 230 Query: 245 LAGHSESGGELIER-DGKKYKLFYGMSSEMAMKKYAGGVAEYRASEGKTVEVPFKGDVEH 303 LAG + + GE+ ++ DG K K + GM+S A + + G + E++ +EG EVPFK + + Sbjct: 231 LAGSAPTPGEVFQKDDGSKVKRYRGMASREAQEAFLGQMHEWKTAEGVATEVPFKENPDG 290 Query: 304 TIRDILGGIRSTCTYVGAAKLKELSRRTTFIRVTQ 338 I DI+GG+RS TY GA + EL R+ ++ VTQ Sbjct: 291 IIADIIGGLRSGLTYAGADSISELQRKLNYVIVTQ 325 >5UQG-A nrPDB Length = 406 Score = 194 bits (493), Expect = 5e-50, Method: Compositional matrix adjust. Identities = 118/356 (33%), Positives = 187/356 (52%), Gaps = 35/356 (9%) Query: 10 LDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFEMAKVLCK 69 L F+DVLLRP S + + EV + + K +P+I+A MDTV A ++ + Sbjct: 32 LTFEDVLLRPGYSEVLPK-EVKIHTKLT----KNITLNMPLISAAMDTVTEHRAAIMMAR 86 Query: 70 FSLFTAVHKHYS---------------------LVQWQEFAGQNPDCLEHLAASSGTGSS 108 +HK+ L + +E+ N D L + G Sbjct: 87 LGGLGVIHKNMDIASQVREVKRVKKSESGGIKDLKKRKEYPDANKDNFGRLRVGAAIGVG 146 Query: 109 DFEQLEQILEAIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEEL 168 ++++ ++EA V + LD A+G+S+ ++ VK ++ ++P ++AGN+ T + L Sbjct: 147 QMDRVDALVEA--GVDVVVLDSAHGHSKGIIDTVKAIKAKYPNLDLIAGNIATAAAAKAL 204 Query: 169 ILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDV 228 +G D +KVGIGPGS+CTTR +GVG PQ+SA+ EC + A+ +I+DGG GD+ Sbjct: 205 CEAGVDAVKVGIGPGSICTTRIVSGVGVPQISAIDECVEEANKFGVPVIADGGIKYSGDI 264 Query: 229 AKAFGAGADFVMLGGMLAGHSESGGELIERDGKKYKLFYGMSSEMAMKK------YAGGV 282 AKA GA VM+G +LAG ES GEL G++YK + GM S AM+K + G Sbjct: 265 AKALAVGASSVMIGSLLAGTDESPGELFTYQGRQYKSYRGMGSLGAMQKGSSDRYFQQGT 324 Query: 283 AEYR-ASEGKTVEVPFKGDVEHTIRDILGGIRSTCTYVGAAKLKELSRRTTFIRVT 337 A+ + EG VP+ G + + +LGG+RS+ YVGA +++ +R F+ +T Sbjct: 325 AQDKLVPEGIEGRVPYVGSIRSVVHQLLGGLRSSMGYVGAKDIEDFQKRAEFVEIT 380 >4MJM-A nrPDB Length = 385 Score = 193 bits (490), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 129/360 (35%), Positives = 189/360 (52%), Gaps = 43/360 (11%) Query: 10 LDFKDVLLRPKRSTLKSRSEVDLTRSFSFRN--SKQTYSGVPIIAANMDTVGTFEMAKVL 67 L F DVLL P +S + L R S + S+ +P+I+A MDTV +MA + Sbjct: 14 LTFDDVLLVPAKSDV-------LPREVSVKTVLSESLQLNIPLISAGMDTVTEADMAIAM 66 Query: 68 CKFSLFTAVHKHYSLVQWQ---------------------EFAGQNPDCLEHL--AASSG 104 + +HK+ S+ Q EF D L A+ G Sbjct: 67 ARQGGLGIIHKNMSIEQQAEQVDKVKRSESGGIKDIEKVIEFPNSAKDKQGRLLVGAAVG 126 Query: 105 TGSSDFEQLEQILEAIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEM 164 + +++ +++A V I LD A+G+S+ ++ VK+VR ++P I+AGNV T E Sbjct: 127 VTADAMTRIDALVKA--SVDAIVLDTAHGHSQGVIDKVKEVRAKYPSLNIIAGNVATAEA 184 Query: 165 VEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAVMECADAA--HGLKGHIISDGGC 222 + LI +GA+++KVGIGPGS+CTTR GVG PQL+AV +CA A HG+ +I+DGG Sbjct: 185 TKALIEAGANVVKVGIGPGSICTTRVVAGVGVPQLTAVYDCATEARKHGIP--VIADGGI 242 Query: 223 SCPGDVAKAFGAGADFVMLGGMLAGHSESGGELIERDGKKYKLFYGMSSEMAMKK----- 277 GD+ KA AGA VMLG M AG +ES GE G+++K++ GM S AM+K Sbjct: 243 KYSGDMVKALAAGAHVVMLGSMFAGVAESPGETEIYQGRQFKVYRGMGSVGAMEKGSKDR 302 Query: 278 YAGGVAEYRASEGKTVEVPFKGDVEHTIRDILGGIRSTCTYVGAAKLKELSRRTTFIRVT 337 Y + EG VP+KG + T+ ++GG+R+ Y GA L+ L FIR++ Sbjct: 303 YFQEGNKKLVPEGIEGRVPYKGPLADTVHQLVGGLRAGMGYCGAQDLEFLRENAQFIRMS 362 >1VRD-A nrPDB Length = 494 Score = 186 bits (471), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 101/247 (40%), Positives = 151/247 (61%), Gaps = 13/247 (5%) Query: 99 LAASSGTGSSDFEQLEQILEAIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGN 158 + A+ GT E++E++++A V I +D A+G+S +E ++ ++ +P ++AGN Sbjct: 228 VGAAVGTSPETMERVEKLVKA--GVDVIVIDTAHGHSRRVIETLEMIKADYPDLPVVAGN 285 Query: 159 VVTGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIIS 218 V T E E LI +GAD +KVG+GPGS+CTTR GVG PQL+AVMEC++ A II+ Sbjct: 286 VATPEGTEALIKAGADAVKVGVGPGSICTTRVVAGVGVPQLTAVMECSEVARKYDVPIIA 345 Query: 219 DGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGELIERDGKKYKLFYGMSSEMAMKKY 278 DGG GD+ KA AGA+ VM+G + AG E+ GE I G+KYK + GM S AM+ Sbjct: 346 DGGIRYSGDIVKALAAGAESVMVGSIFAGTEEAPGETILYQGRKYKAYRGMGSLGAMR-- 403 Query: 279 AGGVAEYRASEGKT------VE--VPFKGDVEHTIRDILGGIRSTCTYVGAAKLKELSRR 330 G A+ EG+ +E VP+KG V+ + ++GG+RS Y+GA +KEL + Sbjct: 404 -SGSADRYGQEGENKFVPEGIEGMVPYKGTVKDVVHQLVGGLRSGMGYIGARTIKELQEK 462 Query: 331 TTFIRVT 337 F+++T Sbjct: 463 AVFVKIT 469 Score = 37.4 bits (85), Expect = 0.011, Method: Compositional matrix adjust. Identities = 21/72 (29%), Positives = 35/72 (48%), Gaps = 5/72 (6%) Query: 10 LDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFEMAKVLCK 69 L F DVLL P+ S + + R ++Q +P+++A MDTV +AK L + Sbjct: 17 LTFDDVLLVPQYSEVLPKD-----VKIDTRLTRQIRINIPLVSAAMDTVTEAALAKALAR 71 Query: 70 FSLFTAVHKHYS 81 +HK+ + Sbjct: 72 EGGIGIIHKNLT 83 >4QJ1-A nrPDB Length = 361 Score = 177 bits (449), Expect = 7e-45, Method: Compositional matrix adjust. Identities = 122/340 (35%), Positives = 186/340 (54%), Gaps = 26/340 (7%) Query: 10 LDFKDVLLRPKRSTLKSRS---EVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFEMAKV 66 L F+D+LL P S + R E LT++ S + +P+I++ MDTV MA Sbjct: 13 LTFEDILLVPNYSEVLPREVSLETKLTKNVSLK--------IPLISSAMDTVTEHLMAVG 64 Query: 67 LCKFSLFTAVHKHYSL-VQWQE-FAGQNPDCLEHLAASSGTGSSDFEQLEQILEAIPQVK 124 + + +HK+ + Q E +N L AA G ++ E+ + ++EA V Sbjct: 65 MARLGGIGIIHKNMDMESQVNEVLKVKNSGGLRVGAA---IGVNEIERAKLLVEA--GVD 119 Query: 125 YICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGS 184 I LD A+G+S + + +K+++ + I+ GNVVT E +ELI +GAD IKVGIGPGS Sbjct: 120 VIVLDSAHGHSLNIIRTLKEIKSKMNIDVIV-GNVVTEEATKELIENGADGIKVGIGPGS 178 Query: 185 VCTTRKKTGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGM 244 +CTTR GVG PQ++A+ +C+ A II+DGG GD+ KA GA VM+G + Sbjct: 179 ICTTRIVAGVGVPQITAIEKCSSVASKFGIPIIADGGIRYSGDIGKALAVGASSVMIGSI 238 Query: 245 LAGHSESGGELIERDGKKYKLFYGMSSEMAMKKYAGG--VAEYR-----ASEGKTVEVPF 297 LAG ES GE YK + GM S AMK +G E R EG V + Sbjct: 239 LAGTEESPGEKELIGDTVYKYYRGMGSVGAMKSGSGDRYFQEKRPENKMVPEGIEGRVKY 298 Query: 298 KGDVEHTIRDILGGIRSTCTYVGAAKLKELSRRTTFIRVT 337 KG++E + ++GG+RS Y+G+A ++EL ++++++ +T Sbjct: 299 KGEMEGVVYQLVGGLRSCMGYLGSASIEELWKKSSYVEIT 338 >1YPF-A nrPDB Length = 336 Score = 177 bits (448), Expect = 8e-45, Method: Compositional matrix adjust. Identities = 119/343 (34%), Positives = 181/343 (52%), Gaps = 32/343 (9%) Query: 10 LDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFEMAKVLCK 69 D++D+ L P + + SRSE D T + K +P++ ANM T+ +A L + Sbjct: 14 FDYEDIQLIPAKCIVNSRSECDTTVTLGKHKFK-----LPVVPANMQTIIDERIATYLAE 68 Query: 70 FSLFTAVH-----KHYSLVQWQEFAGQNPDCLEHLAASSGTGSSDFEQLEQILEAIPQVK 124 + F +H K S ++ + G + S G ++E ++Q+ + Sbjct: 69 NNYFYIMHRFQPEKRISFIRDMQSRGLIA------SISVGVKEDEYEFVQQLAAEHLTPE 122 Query: 125 YICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGS 184 YI +D+A+G+S + ++ ++K P+ ++AGNV T E V EL +GAD KVGIGPG Sbjct: 123 YITIDIAHGHSNAVINMIQHIKKHLPESFVIAGNVGTPEAVRELENAGADATKVGIGPGK 182 Query: 185 VCTTRKKTGVGY--PQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLG 242 VC T+ KTG G QL+A+ CA AA II+DGG GDVAK+ GA VM+G Sbjct: 183 VCITKIKTGFGTGGWQLAALRWCAKAA---SKPIIADGGIRTNGDVAKSIRFGATMVMIG 239 Query: 243 GMLAGHSESGGELIERDGKKYKLFYGMSSEMAMKKYAGGVAEYRASEGKTVEVPFKGDVE 302 + AGH ES GE IE+DGK YK ++G +SE E + EGK + V KG +E Sbjct: 240 SLFAGHEESPGETIEKDGKLYKEYFGSASEFQK-------GEKKNVEGKKMFVEHKGSLE 292 Query: 303 HTIRDILGGIRSTCTYVGAAKLKELSRRTTFIRVTQQVNPIFS 345 T+ ++ ++S+ +Y G KL + R ++ V N IF+ Sbjct: 293 DTLIEMEQDLQSSISYAGGTKLDSI-RTVDYVVVK---NSIFN 331 >4FEZ-A nrPDB Length = 388 Score = 176 bits (445), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 114/358 (31%), Positives = 184/358 (51%), Gaps = 37/358 (10%) Query: 10 LDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFEMAKVLCK 69 L F DVLL P ST+ + T R +K +P+++A+MDTV +A L + Sbjct: 14 LTFDDVLLVPAHSTV-----LPNTADLRTRLTKNIALNIPMVSASMDTVTEARLAIALAQ 68 Query: 70 FSLFTAVHKHYSLVQW---------------QEF--AGQNPDCLE------HLAASSGTG 106 +HK+ S+ Q ++F A P+ + + A+ G Sbjct: 69 EGGIGFIHKNMSIEQQAAQVHQVKIFESGGAKDFHKAESKPNACKDEQGRLRVGAAVGAA 128 Query: 107 SSDFEQLEQILEAIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVE 166 + E+++ ++EA V + +D ++G+SE ++ +++ R +P I+ GNV T E Sbjct: 129 PGNEERVKALVEA--GVDVLLIDSSHGHSEGVLQRIRETRAAYPHLEIIGGNVATAEGAR 186 Query: 167 ELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPG 226 LI +G +KVGIGPGS+CTTR TGVG PQ++A+ + A A+ +I+DGG G Sbjct: 187 ALIEAGVSAVKVGIGPGSICTTRIVTGVGVPQITAIADAAGVANEYGIPVIADGGIRFSG 246 Query: 227 DVAKAFGAGADFVMLGGMLAGHSESGGELIERDGKKYKLFYGMSSEMAMKKYAG------ 280 D++KA AGA VM+G M AG E+ GE+I G+ YK + GM S AM K + Sbjct: 247 DISKAIAAGASCVMVGSMFAGTEEAPGEVILYQGRSYKAYRGMGSLGAMSKGSSDRYFQT 306 Query: 281 -GVAEYRASEGKTVEVPFKGDVEHTIRDILGGIRSTCTYVGAAKLKELSRRTTFIRVT 337 A+ EG + +KG ++ I +GG+RS G+A +++L + F+R++ Sbjct: 307 DNAADKLVPEGIEGRIAYKGHLKEIIHQQMGGLRSCMGLTGSATVEDLRTKAQFVRIS 364 >1EEP-A nrPDB Length = 404 Score = 175 bits (443), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 122/396 (30%), Positives = 191/396 (48%), Gaps = 65/396 (16%) Query: 1 MPHIDNDVKLDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGT 60 MP+ L F DV L P++S++ SEV L + K +P +++ MDTV Sbjct: 1 MPNKITKEALTFDDVSLIPRKSSVLP-SEVSLKTQLT----KNISLNIPFLSSAMDTVTE 55 Query: 61 FEMAKVLCKFSLFTAVHKHYSL------------VQWQEFAGQNPDCLE----------H 98 +MA + K +HK+ S+ ++Q+ N D E H Sbjct: 56 SQMAIAIAKEGGIGIIHKNMSIEAQRKEIEKVKTYKFQKTINTNGDTNEQKPEIFTAKQH 115 Query: 99 LAASSGTGSS-------------------------DFEQLEQILEAI-PQVKYICLDVAN 132 L S ++ D + +E++ E + V + +D A+ Sbjct: 116 LEKSDAYKNAEHKEDFPNACKDLNNKLRVGAAVSIDIDTIERVEELVKAHVDILVIDSAH 175 Query: 133 GYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTTRKKT 192 G+S +E +K ++ ++P ++AGN+VT E +LI GAD +KVGIGPGS+CTTR Sbjct: 176 GHSTRIIELIKKIKTKYPNLDLIAGNIVTKEAALDLISVGADCLKVGIGPGSICTTRIVA 235 Query: 193 GVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESG 252 GVG PQ++A+ + +A + II+DGG GDV KA AGAD VM+G + AG ES Sbjct: 236 GVGVPQITAICDVYEACNNTNICIIADGGIRFSGDVVKAIAAGADSVMIGNLFAGTKESP 295 Query: 253 GELIERDGKKYKLFYGMSSEMAMKKYAGGVAEY----------RASEGKTVEVPFKGDVE 302 E I +GKK+K + GM S AMK+ G + Y EG VP+ G ++ Sbjct: 296 SEEIIYNGKKFKSYVGMGSISAMKR--GSKSRYFQLENNEPKKLVPEGIEGMVPYSGKLK 353 Query: 303 HTIRDILGGIRSTCTYVGAAKLKELSRRTTFIRVTQ 338 + + GG+ S Y+GAA + +L + F++++ Sbjct: 354 DILTQLKGGLMSGMGYLGAATISDLKINSKFVKISH 389 >3TSB-A nrPDB Length = 511 Score = 172 bits (437), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 100/246 (40%), Positives = 148/246 (60%), Gaps = 11/246 (4%) Query: 99 LAASSGTGSSDFEQLEQILEAIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGN 158 + A+ G + +++ +++A V I LD A+G+S+ ++ VK+VR ++P I+AGN Sbjct: 247 VGAAVGVTADAMTRIDALVKA--SVDAIVLDTAHGHSQGVIDKVKEVRAKYPSLNIIAGN 304 Query: 159 VVTGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAVMECADAA--HGLKGHI 216 V T E + LI +GA+++KVGIGPGS+CTTR GVG PQL+AV +CA A HG+ + Sbjct: 305 VATAEATKALIEAGANVVKVGIGPGSICTTRVVAGVGVPQLTAVYDCATEARKHGIP--V 362 Query: 217 ISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGELIERDGKKYKLFYGMSSEMAMK 276 I+DGG GD+ KA AGA VMLG M AG +ES GE G+++K++ GM S AM+ Sbjct: 363 IADGGIKYSGDMVKALAAGAHVVMLGSMFAGVAESPGETEIYQGRQFKVYRGMGSVGAME 422 Query: 277 K-----YAGGVAEYRASEGKTVEVPFKGDVEHTIRDILGGIRSTCTYVGAAKLKELSRRT 331 K Y + EG VP+KG + T+ ++GG+R+ Y GA L+ L Sbjct: 423 KGSKDRYFQEGNKKLVPEGIEGRVPYKGPLADTVHQLVGGLRAGMGYCGAQDLEFLRENA 482 Query: 332 TFIRVT 337 FIR++ Sbjct: 483 QFIRMS 488 Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust. Identities = 26/80 (32%), Positives = 39/80 (48%), Gaps = 9/80 (11%) Query: 10 LDFKDVLLRPKRSTLKSRSEVDLTRSFSFRN--SKQTYSGVPIIAANMDTVGTFEMAKVL 67 L F DVLL P +S + L R S + S+ +P+I+A MDTV +MA + Sbjct: 35 LTFDDVLLVPAKSDV-------LPREVSVKTVLSESLQLNIPLISAGMDTVTEADMAIAM 87 Query: 68 CKFSLFTAVHKHYSLVQWQE 87 + +HK+ S+ Q E Sbjct: 88 ARQGGLGIIHKNMSIEQQAE 107 >3FFS-A nrPDB Length = 400 Score = 171 bits (433), Expect = 4e-43, Method: Compositional matrix adjust. Identities = 119/379 (31%), Positives = 187/379 (49%), Gaps = 62/379 (16%) Query: 10 LDFKDVLLRPKRSTLKSRS---EVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFEMAKV 66 L F+D+LL P S + R E LT++ S + +P+I++ MDTV MA Sbjct: 10 LTFEDILLVPNYSEVLPREVSLETKLTKNVSLK--------IPLISSAMDTVTEHLMAVG 61 Query: 67 LCKFSLFTAVHKHYSL----------VQW------------------------------- 85 + + +HK+ + W Sbjct: 62 MARLGGIGIIHKNMDMESQVNEVLKVKNWISNLEKNESTPDQNLDKESTDGKDTKSNNNI 121 Query: 86 QEFAGQNPDCLEHLAASSGTGSSDFEQLEQILEAIPQVKYICLDVANGYSEHFVEFVKDV 145 ++ +N D L + G ++ E+ + ++EA V I LD A+G+S + + +K++ Sbjct: 122 DAYSNENLDNKGRLRVGAAIGVNEIERAKLLVEA--GVDVIVLDSAHGHSLNIIRTLKEI 179 Query: 146 RKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAVMEC 205 + + ++ GNVVT E +ELI +GAD IKVGIGPGS+CTTR GVG PQ++A+ +C Sbjct: 180 KSKM-NIDVIVGNVVTEEATKELIENGADGIKVGIGPGSICTTRIVAGVGVPQITAIEKC 238 Query: 206 ADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGELIERDGKKYKL 265 + A II+DGG GD+ KA GA VM+G +LAG ES GE YK Sbjct: 239 SSVASKFGIPIIADGGIRYSGDIGKALAVGASSVMIGSILAGTEESPGEKELIGDTVYKY 298 Query: 266 FYGMSSEMAMKKYAGG--VAEYR-----ASEGKTVEVPFKGDVEHTIRDILGGIRSTCTY 318 + GM S AMK +G E R EG V +KG++E + ++GG+RS Y Sbjct: 299 YRGMGSVGAMKSGSGDRYFQEKRPENKMVPEGIEGRVKYKGEMEGVVYQLVGGLRSCMGY 358 Query: 319 VGAAKLKELSRRTTFIRVT 337 +G+A ++EL ++++++ +T Sbjct: 359 LGSASIEELWKKSSYVEIT 377 >1ZFJ-A nrPDB Length = 491 Score = 171 bits (432), Expect = 6e-43, Method: Compositional matrix adjust. Identities = 99/247 (40%), Positives = 136/247 (55%), Gaps = 10/247 (4%) Query: 99 LAASSGTGSSDFEQLEQILEAIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGN 158 +AA+ G S FE+ E + EA I +D A+G+S + + ++R FP T++AGN Sbjct: 224 VAAAVGVTSDTFERAEALFEA--GADAIVIDTAHGHSAGVLRKIAEIRAHFPNRTLIAGN 281 Query: 159 VVTGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIIS 218 + T E L +G D++KVGIGPGS+CTTR GVG PQ++A+ + A A II+ Sbjct: 282 IATAEGARALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQVTAIYDAAAVAREYGKTIIA 341 Query: 219 DGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGELIERDGKKYKLFYGMSSEMAMKK- 277 DGG GD+ KA AG + VMLG M AG E+ GE G+KYK + GM S AMKK Sbjct: 342 DGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIYQGRKYKTYRGMGSIAAMKKG 401 Query: 278 -----YAGGVAEYR--ASEGKTVEVPFKGDVEHTIRDILGGIRSTCTYVGAAKLKELSRR 330 + G V E EG V +KG + +LGGIRS YVGA ++EL Sbjct: 402 SSDRYFQGSVNEANKLVPEGIEGRVAYKGAASDIVFQMLGGIRSGMGYVGAGDIQELHEN 461 Query: 331 TTFIRVT 337 F+ ++ Sbjct: 462 AQFVEMS 468 Score = 38.1 bits (87), Expect = 0.006, Method: Compositional matrix adjust. Identities = 25/76 (32%), Positives = 36/76 (47%), Gaps = 5/76 (6%) Query: 12 FKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFEMAKVLCKFS 71 F DVLL P S + +EVDL + +PII A MDTV +MA + + Sbjct: 14 FDDVLLIPAESHVLP-NEVDLKTKLA----DNLTLNIPIITAAMDTVTGSKMAIAIARAG 68 Query: 72 LFTAVHKHYSLVQWQE 87 +HK+ S+ + E Sbjct: 69 GLGVIHKNMSITEQAE 84 >4FXS-A nrPDB Length = 496 Score = 155 bits (392), Expect = 3e-38, Method: Compositional matrix adjust. Identities = 87/246 (35%), Positives = 140/246 (56%), Gaps = 9/246 (3%) Query: 99 LAASSGTGSSDFEQLEQILEAIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGN 158 + A+ G + E+++ ++EA V + +D ++G+SE ++ +++ R +P I+ GN Sbjct: 222 VGAAVGAAPGNEERVKALVEA--GVDVLLIDSSHGHSEGVLQRIRETRAAYPHLEIIGGN 279 Query: 159 VVTGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIIS 218 V T E LI +G +KVGIGPGS+CTTR TGVG PQ++A+ + A A+ +I+ Sbjct: 280 VATAEGARALIEAGVSAVKVGIGPGSICTTRIVTGVGVPQITAIADAAGVANEYGIPVIA 339 Query: 219 DGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGELIERDGKKYKLFYGMSSEMAMKKY 278 DGG GD++KA AGA VM+G M AG E+ GE+I G+ YK + GM S AM K Sbjct: 340 DGGIRFSGDISKAIAAGASCVMVGSMFAGTEEAPGEVILYQGRSYKAYRGMGSLGAMSKG 399 Query: 279 AG-------GVAEYRASEGKTVEVPFKGDVEHTIRDILGGIRSTCTYVGAAKLKELSRRT 331 + A+ EG + +KG ++ I +GG+RS G+A +++L + Sbjct: 400 SSDRYFQTDNAADKLVPEGIEGRIAYKGHLKEIIHQQMGGLRSCMGLTGSATVEDLRTKA 459 Query: 332 TFIRVT 337 F+R++ Sbjct: 460 QFVRIS 465 Score = 38.9 bits (89), Expect = 0.003, Method: Compositional matrix adjust. Identities = 24/76 (31%), Positives = 36/76 (47%), Gaps = 5/76 (6%) Query: 10 LDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFEMAKVLCK 69 L F DVLL P ST+ T R +K +P+++A+MDTV +A L + Sbjct: 11 LTFDDVLLVPAHSTVLPN-----TADLRTRLTKNIALNIPMVSASMDTVTEARLAIALAQ 65 Query: 70 FSLFTAVHKHYSLVQW 85 +HK+ S+ Q Sbjct: 66 EGGIGFIHKNMSIEQQ 81 >5UPU-A nrPDB Length = 407 Score = 152 bits (385), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 112/354 (31%), Positives = 180/354 (50%), Gaps = 28/354 (7%) Query: 2 PHIDNDVKLDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTF 61 PH + L F DVLL P S + V T S + +K+ VP++++ MDTV Sbjct: 40 PHKVAMLGLTFDDVLLLPAASDV-----VPATADTSSQLTKKIRLKVPLVSSAMDTVTES 94 Query: 62 EMAKVLCKFSLFTAVHKHYSLVQWQ---EFAGQNPDCLEHLAASSGTGSSDFEQLEQILE 118 MA + + +H++ + + E ++ L + A+ G G + + +++ Sbjct: 95 RMAIAMARAGGMGVLHRNLPVAEQAGQVEMVKRSGGLL--VGAAVGVGGDAWVRAMMLVD 152 Query: 119 AIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQHT-IMAGNVVTGEMVEELILSGADIIK 177 A V + +D A+ ++ ++ V ++ ++ GNV T L+ +GAD +K Sbjct: 153 A--GVDVLVVDTAHAHNRLVLDMVGKLKSEVGDRVEVVGGNVATRSAAAALVDAGADAVK 210 Query: 178 VGIGPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGAD 237 VG+GPGS+CTTR GVG PQ++A++E A +I+DGG GD+AKA AGA Sbjct: 211 VGVGPGSICTTRVVAGVGAPQITAILEAVAACRPAGVPVIADGGLQYSGDIAKALAAGAS 270 Query: 238 FVMLGGMLAGHSESGGELIERDGKKYKLFYGMSSEMAMKKYAGGV--------AEYRASE 289 MLG +LAG +E+ GELI +GK+YK + GM S AM+ G A+ SE Sbjct: 271 TAMLGSLLAGTAEAPGELIFVNGKQYKSYRGMGSLGAMRGRGGATSYSKDRYFADDALSE 330 Query: 290 GKTV------EVPFKGDVEHTIRDILGGIRSTCTYVGAAKLKELSRRTTFIRVT 337 K V VPF+G + I + GG+R+ Y G+ + E+ ++ F+R+T Sbjct: 331 DKLVPEGIEGRVPFRGPLSSVIHQLTGGLRAAMGYTGSPTI-EVLQQAQFVRIT 383 >5AHL-A nrPDB Length = 400 Score = 150 bits (380), Expect = 6e-37, Method: Compositional matrix adjust. Identities = 118/362 (32%), Positives = 180/362 (49%), Gaps = 48/362 (13%) Query: 10 LDFKDVLL-------RPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFE 62 L F DVLL PK +LK+R LTR +P+++A MDTV Sbjct: 29 LTFDDVLLIPGYSEVLPKDVSLKTR----LTRGIELN--------IPLVSAAMDTVTEAR 76 Query: 63 MAKVLCKFSLFTAVHKHYSLVQWQ-----------------EFAGQNPDCLEHLAASSGT 105 +A + + +HK+ + Q A ++ + A+ GT Sbjct: 77 LAIAMAQEGGIGIIHKNMGIEQQAAEVRKVKKHETAKAKTYPLASKDEQGRLRVGAAVGT 136 Query: 106 GSSDFEQLEQILEAIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMV 165 G+ E++ ++ A V + +D A+G+S+ +E V+ V++ FP ++ GN+ T E Sbjct: 137 GADTGERVAALVAA--GVDVVVVDTAHGHSKGVIERVRWVKQTFPDVQVIGGNIATAEAA 194 Query: 166 EELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIISDGGCSCP 225 + L +GAD +KVGIGPGS+CTTR GVG PQ+SA+ A A G +I+DGG Sbjct: 195 KALAEAGADAVKVGIGPGSICTTRIVAGVGVPQISAIANVAAALEGTGVPLIADGGIRFS 254 Query: 226 GDVAKAFGAGADFVMLGGMLAGHSESGGELIERDGKKYKLFYGMSSEMAMKKYAGGV--- 282 GD+AKA AGA VM+G M AG E+ GE+ G+ YK + GM S AM G Sbjct: 255 GDLAKAMVAGAYCVMMGSMFAGTEEAPGEIELFQGRSYKSYRGMGSLGAMSGSQGSSDRY 314 Query: 283 -------AEYRASEGKTVEVPFKGDVEHTIRDILGGIRSTCTYVGAAKLKELSRRTTFIR 335 AE EG VP+KG + + ++GG+R+ Y G+A ++++ + F+R Sbjct: 315 FQDASAGAEKLVPEGIEGRVPYKGALSAIVHQLMGGLRAAMGYTGSADIQQMRTQPQFVR 374 Query: 336 VT 337 +T Sbjct: 375 IT 376 >2CU0-A nrPDB Length = 486 Score = 146 bits (368), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 86/224 (38%), Positives = 131/224 (58%), Gaps = 11/224 (4%) Query: 123 VKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGP 182 V I +D A+ ++ ++ +K++R++ I+ GN+ + V++L AD +KVGIGP Sbjct: 241 VDVIVVDTAHAHNLKAIKSMKEMRQKVDADFIV-GNIANPKAVDDLTF--ADAVKVGIGP 297 Query: 183 GSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLG 242 GS+CTTR GVG PQ++AV AD A ++I+DGG GD+ KA AGAD VMLG Sbjct: 298 GSICTTRIVAGVGVPQITAVAMVADRAQEYGLYVIADGGIRYSGDIVKAIAAGADAVMLG 357 Query: 243 GMLAGHSESGGELIERDGKKYKLFYGMSSEMAMKK------YAGGVAEYR--ASEGKTVE 294 +LAG E+ G+ + +G+KYK + GM S AM K Y GG + R EG Sbjct: 358 NLLAGTKEAPGKEVIINGRKYKQYRGMGSLGAMMKGGAERYYQGGYMKTRKFVPEGVEGV 417 Query: 295 VPFKGDVEHTIRDILGGIRSTCTYVGAAKLKELSRRTTFIRVTQ 338 VP++G V + ++GG+++ YVGA ++EL + F+ +T Sbjct: 418 VPYRGTVSEVLYQLVGGLKAGMGYVGARNIRELKEKGEFVIITH 461 Score = 38.5 bits (88), Expect = 0.005, Method: Compositional matrix adjust. Identities = 22/76 (28%), Positives = 41/76 (53%), Gaps = 5/76 (6%) Query: 12 FKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFEMAKVLCKFS 71 F DVLL P+ + ++ + +VD+ S R + +PI++A MDTV +EMA + + Sbjct: 17 FDDVLLIPQATEVEPK-DVDV----STRITPNVKLNIPILSAAMDTVTEWEMAVAMAREG 71 Query: 72 LFTAVHKHYSLVQWQE 87 +H++ + + E Sbjct: 72 GLGVIHRNMGIEEQVE 87 >4XTI-A nrPDB Length = 413 Score = 139 bits (349), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 108/349 (30%), Positives = 168/349 (48%), Gaps = 35/349 (10%) Query: 10 LDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFEMAKVLCK 69 L + D L+ P + S SEV L S R +K+ P +++ MDTV +MA + Sbjct: 39 LTYNDFLVLPGKIDFPS-SEVVL----SSRLTKKITLNAPFVSSPMDTVTEADMAIHMAL 93 Query: 70 FSLFTAVHKHYSLVQWQE----------------FAGQNPDCLEHL-AASSGTGSSDFEQ 112 +H + + + E A ++ D + L A+ GT +D ++ Sbjct: 94 LGGIGIIHHNCTAEEQAEMVRRVKKYENGSQDGPLASKSADTKQLLCGAAIGTIDADRQR 153 Query: 113 LEQILEAIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSG 172 L ++EA + + LD + G S + +K +++ FP ++AGNVVT E LI +G Sbjct: 154 LAMLVEA--GLDVVVLDSSQGNSVFQINMIKWIKETFPDLQVIAGNVVTREQAASLIHAG 211 Query: 173 ADIIKVGIGPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAF 232 AD +++G+G GS+C T++ G PQ +AV A+ I+DGG G + KA Sbjct: 212 ADGLRIGMGSGSICITQEVMACGRPQGTAVYNVTQFANQFGVPCIADGGVQNIGHITKAI 271 Query: 233 GAGADFVMLGGMLAGHSESGGELIERDGKKYKLFYGMSSEMAMKK--YAGGVAEYR---- 286 GA VM+GGMLAG +ES GE RDGK+ K + GM S AM+K G A R Sbjct: 272 ALGASTVMMGGMLAGTTESPGEYFFRDGKRLKTYRGMGSIDAMQKTDVKGNAATSRYFSE 331 Query: 287 -----ASEGKTVEVPFKGDVEHTIRDILGGIRSTCTYVGAAKLKELSRR 330 ++G T V KG ++ I + G++ +C +G L E + Sbjct: 332 SDKVLVAQGVTGSVIDKGSIKKYIPYLYNGLQHSCQDIGVRSLVEFREK 380 >4DQW-A nrPDB Length = 509 Score = 138 bits (347), Expect = 4e-33, Method: Compositional matrix adjust. Identities = 85/216 (39%), Positives = 125/216 (57%), Gaps = 10/216 (4%) Query: 132 NGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTTRKK 191 +G+S+ +E V+ V++ FP ++ GN+ T E + L +GAD +KVGIGPGS+CTTR Sbjct: 270 HGHSKGVIERVRWVKQTFPDVQVIGGNIATAEAAKALAEAGADAVKVGIGPGSICTTRIV 329 Query: 192 TGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSES 251 GVG PQ+SA+ A A G +I+DGG GD+AKA AGA VM+G M AG E+ Sbjct: 330 AGVGVPQISAIANVAAALEGTGVPLIADGGIRFSGDLAKAMVAGAYCVMMGSMFAGTEEA 389 Query: 252 GGELIERDGKKYKLFYGMSSEMAMK-------KY---AGGVAEYRASEGKTVEVPFKGDV 301 GE+ G+ YK + GM S AM +Y A AE EG VP+KG + Sbjct: 390 PGEIELFQGRSYKSYRGMGSLGAMSGSQGSSDRYFQDASAGAEKLVPEGIEGRVPYKGAL 449 Query: 302 EHTIRDILGGIRSTCTYVGAAKLKELSRRTTFIRVT 337 + ++GG+R+ Y G+A ++++ + F+R+T Sbjct: 450 SAIVHQLMGGLRAAMGYTGSADIQQMRTQPQFVRIT 485 Score = 32.3 bits (72), Expect = 0.30, Method: Compositional matrix adjust. Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 19/82 (23%) Query: 10 LDFKDVLL-------RPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFE 62 L F DVLL PK +LK+R LTR +P+++A MDTV Sbjct: 29 LTFDDVLLIPGYSEVLPKDVSLKTR----LTRGIELN--------IPLVSAAMDTVTEAR 76 Query: 63 MAKVLCKFSLFTAVHKHYSLVQ 84 +A + + +HK+ + Q Sbjct: 77 LAIAMAQEGGIGIIHKNMGIEQ 98 >4Z87-A nrPDB Length = 525 Score = 130 bits (327), Expect = 8e-31, Method: Compositional matrix adjust. Identities = 88/259 (33%), Positives = 134/259 (51%), Gaps = 14/259 (5%) Query: 84 QWQEFAGQNPDCLEHL-AASSGTGSSDFEQLEQILEAIPQVKYICLDVANGYSEHFVEFV 142 Q A ++ D + L A+ GT +D ++L ++EA + + LD + G S + + Sbjct: 236 QSYPLASKSADTKQLLCGAAIGTIDADRQRLAMLVEA--GLDVVVLDSSQGNSVFQINMI 293 Query: 143 KDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAV 202 K +++ FP ++AGNVVT E LI +GAD +++G+G GS+C T++ G PQ +AV Sbjct: 294 KWIKETFPDLQVIAGNVVTREQAASLIHAGADGLRIGMGSGSICITQEVMACGRPQGTAV 353 Query: 203 MECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGELIERDGKK 262 A+ I+DGG G + KA GA VM+GGMLAG +ES GE RDGK+ Sbjct: 354 YNVTQFANQFGVPCIADGGVQNIGHITKAIALGASTVMMGGMLAGTTESPGEYFFRDGKR 413 Query: 263 YKLFYGMSSEMAMKK--YAGGVAEYR---------ASEGKTVEVPFKGDVEHTIRDILGG 311 K + GM S AM+K G A R ++G T V KG ++ I + G Sbjct: 414 LKTYRGMGSIDAMQKTDVKGNAATSRYFSESDKVLVAQGVTGSVIDKGSIKKYIPYLYNG 473 Query: 312 IRSTCTYVGAAKLKELSRR 330 ++ +C +G L E + Sbjct: 474 LQHSCQDIGVRSLVEFREK 492 >4AF0-B nrPDB Length = 556 Score = 125 bits (315), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 76/206 (36%), Positives = 121/206 (58%), Gaps = 3/206 (1%) Query: 84 QWQEFAGQNPDCLE-HLAASSGTGSSDFEQLEQILEAIPQVKYICLDVANGYSEHFVEFV 142 Q +A + P+ + + A+ GT D ++L+ + EA + + LD + G S + +EF+ Sbjct: 256 QNYPYASKVPESKQLYCGAAIGTRPGDKDRLKLLAEA--GLDVVVLDSSQGNSVYQIEFI 313 Query: 143 KDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAV 202 K +++ +P+ ++AGNVVT E +LI +GAD +++G+G GS+C T++ VG PQ +AV Sbjct: 314 KWIKQTYPKIDVIAGNVVTREQAAQLIAAGADGLRIGMGSGSICITQEVMAVGRPQGTAV 373 Query: 203 MECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGELIERDGKK 262 A+ A I+DGG G +AKA GA VM+GG+LAG +ES GE +GK+ Sbjct: 374 YAVAEFASRFGIPCIADGGIGNIGHIAKALALGASAVMMGGLLAGTTESPGEYFYHEGKR 433 Query: 263 YKLFYGMSSEMAMKKYAGGVAEYRAS 288 K++ GM S AM+ G A + S Sbjct: 434 VKVYRGMGSIEAMEHTQRGSASGKRS 459 >6I0M-A nrPDB Length = 517 Score = 121 bits (303), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 74/262 (28%), Positives = 131/262 (50%), Gaps = 7/262 (2%) Query: 73 FTAVHKHYSLVQWQEFAGQNPDCLEHLAASSGTGSSDFEQLEQILEAIPQVKYICLDVAN 132 A+ L + +++ + D + L + G+ + ++ L A V + LD + Sbjct: 221 LVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQ 280 Query: 133 GYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTTRKKT 192 G S + +K ++ ++P ++ GNVVT + LI +G D ++VG+G GS+C T++ Sbjct: 281 GNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVL 340 Query: 193 GVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESG 252 G PQ +AV + ++ A +I+DGG G +AKA GA VM+G +LA +E+ Sbjct: 341 ACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAP 400 Query: 253 GELIERDGKKYKLFYGMSSEMAMKKYAGGVAEY-------RASEGKTVEVPFKGDVEHTI 305 GE DG + K + GM S AM K+ Y + ++G + V KG + + Sbjct: 401 GEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFV 460 Query: 306 RDILGGIRSTCTYVGAAKLKEL 327 ++ GI+ +C +GA L ++ Sbjct: 461 PYLIAGIQHSCQDIGAKSLTQV 482 >1JCN-A nrPDB Length = 514 Score = 118 bits (295), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 76/234 (32%), Positives = 123/234 (52%), Gaps = 9/234 (3%) Query: 101 ASSGTGSSDFEQLEQILEAIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGNVV 160 A+ GT D +L+ + +A V I LD + G S + + V +++++P ++ GNVV Sbjct: 248 AAVGTREDDKYRLDLLTQA--GVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVV 305 Query: 161 TGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIISDG 220 T + LI +G D ++VG+G GS+C T++ G PQ +AV + A+ A II+DG Sbjct: 306 TAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADG 365 Query: 221 GCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGELIERDGKKYKLFYGMSSEMAMKKYAG 280 G G V KA GA VM+G +LA +E+ GE DG + K + GM S AM+K + Sbjct: 366 GIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSS 425 Query: 281 GVAEY-------RASEGKTVEVPFKGDVEHTIRDILGGIRSTCTYVGAAKLKEL 327 Y + ++G + + KG ++ + ++ GI+ C +GA L L Sbjct: 426 SQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVL 479 >1AK5-A nrPDB Length = 503 Score = 78.2 bits (191), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 75/255 (29%), Positives = 125/255 (49%), Gaps = 13/255 (5%) Query: 94 DCLEHLAASSGTGSSDF-EQLEQILEAIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQH 152 D + +G + DF E++ ++EA V +C+D ++G+SE + +R+++ Sbjct: 227 DSQKRYLVGAGINTRDFRERVPALVEAGADV--LCIDSSDGFSEWQKITIGWIREKYGDK 284 Query: 153 T-IMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAVMECADAAH- 210 + AGN+V GE L +GAD IK+GIG GS+C TR++ G+G Q +AV++ + Sbjct: 285 VKVGAGNIVDGEGFRYLADAGADFIKIGIGGGSICITREQKGIGRGQATAVIDVVAERNK 344 Query: 211 -----GLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGELIERDGKKYKL 265 G+ + SDGG + A GADF+MLG A ES + +G K Sbjct: 345 YFEETGIYIPVCSDGGIVYDYHMTLALAMGADFIMLGRYFARFEESPTRKVTINGSVMKE 404 Query: 266 FYGMSSEMA--MKKY-AGGVAEYRASEGKTVEVPFKGDVEHTIRDILGGIRSTCTYVGAA 322 ++G S A ++Y GG + EG VP+ G ++ + L ++ST GA Sbjct: 405 YWGEGSSRARNWQRYDLGGKQKLSFEEGVDSYVPYAGKLKDNVEASLNKVKSTMCNCGAL 464 Query: 323 KLKELSRRTTFIRVT 337 + +L + V+ Sbjct: 465 TIPQLQSKAKITLVS 479 >5FIR-A nrPDB Length = 636 Score = 32.0 bits (71), Expect = 0.39, Method: Compositional matrix adjust. Identities = 32/127 (25%), Positives = 48/127 (37%), Gaps = 22/127 (17%) Query: 202 VMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGELIERDGK 261 +M+ G H + C C GA AD +MLG +A H + + E + Sbjct: 209 IMDYVRKQRGNPAHDPNTVHCLC--------GADADLIMLG--IATHEANFNIIREEFVQ 258 Query: 262 KYKLFYGMSSEMAMKKYAGGVAEYRASEGKTVEVPFKGDVEHTIRDILGGIRSTCTYVGA 321 + K F + + + EY E +PFK DVE + D + C +VG Sbjct: 259 REKNFIFLRIPV--------LREYLEKELSMPNLPFKFDVERALDDWV----FLCFFVGN 306 Query: 322 AKLKELS 328 L L Sbjct: 307 DFLPHLP 313 >4V4P-AP nrPDB Length = 138 Score = 30.4 bits (67), Expect = 1.2, Method: Compositional matrix adjust. Identities = 18/71 (25%), Positives = 34/71 (47%), Gaps = 9/71 (12%) Query: 93 PDCLEHLAASSGTGSSDFE--------QLEQILEAIPQVKYICLDVANGYSEHFVEFVKD 144 P E+++ G G + F+ Q+E ++E Q+++ L+ A + FV+ Sbjct: 4 PTRREYISGIPGKGIAQFKMGNNTYPAQVENVVEKPVQIRHNALEAARNAANRFVQNSGK 63 Query: 145 VR-KRFPQHTI 154 R ++FP H I Sbjct: 64 FRIRKFPFHVI 74 >6HIS-A nrPDB Length = 445 Score = 28.9 bits (63), Expect = 3.1, Method: Compositional matrix adjust. Identities = 12/34 (35%), Positives = 22/34 (64%), Gaps = 2/34 (5%) Query: 115 QILEAIPQVKYICLDVANGYSEHFVEFVKDVRKR 148 ++LE PQ K +D++N Y+E ++F +R+R Sbjct: 181 ELLEVFPQFKEFSIDISNSYAE--MKFYVIIRRR 212 >1SVD-A nrPDB Length = 473 Score = 28.5 bits (62), Expect = 5.1, Method: Compositional matrix adjust. Identities = 12/29 (41%), Positives = 16/29 (55%) Query: 273 MAMKKYAGGVAEYRASEGKTVEVPFKGDV 301 MA+KKY+ GV EYR + P D+ Sbjct: 1 MAVKKYSAGVKEYRQTYWMPEYTPLDSDI 29 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2BWG-A nrPDB 458 e-129 2C6Q-A nrPDB 444 e-125 5UQG-A nrPDB 416 e-117 4MJM-A nrPDB 415 e-116 4FEZ-A nrPDB 413 e-116 1EEP-A nrPDB 402 e-112 3FFS-A nrPDB 401 e-112 4QJ1-A nrPDB 399 e-112 4XTI-A nrPDB 389 e-108 3R2G-A nrPDB 378 e-105 5AHL-A nrPDB 366 e-101 5UPU-A nrPDB 364 e-101 3TSB-A nrPDB 347 5e-96 1VRD-A nrPDB 345 1e-95 4FXS-A nrPDB 338 2e-93 1YPF-A nrPDB 335 2e-92 1ZFJ-A nrPDB 333 6e-92 6I0M-A nrPDB 318 3e-87 4Z87-A nrPDB 317 5e-87 1JCN-A nrPDB 313 7e-86 4AF0-B nrPDB 299 1e-81 2CU0-A nrPDB 296 1e-80 4DQW-A nrPDB 293 7e-80 1AK5-A nrPDB 254 5e-68 Sequences not found previously or not previously below threshold: 6BFG-A nrPDB 54 1e-07 2A85-A nrPDB 54 1e-07 6DVI-A nrPDB 53 2e-07 5ZBN-A nrPDB 49 3e-06 1AL8-A nrPDB 45 3e-05 4N6F-A nrPDB 45 5e-05 2CDH-0 nrPDB 43 2e-04 2GJN-A nrPDB 43 2e-04 1P0K-A nrPDB 42 4e-04 2RDU-A nrPDB 41 6e-04 5GVH-A nrPDB 41 7e-04 3SGZ-A nrPDB 40 0.001 5ZKN-A nrPDB 40 0.001 5LSM-A nrPDB 39 0.003 2J6X-A nrPDB 38 0.005 3BW4-A nrPDB 37 0.011 1YXY-A nrPDB 37 0.016 4Q4K-A nrPDB 36 0.026 4JEJ-A nrPDB 36 0.030 1TYG-A nrPDB 35 0.037 2Z6J-A nrPDB 35 0.045 1H1Z-A nrPDB 35 0.062 1VHC-A nrPDB 34 0.081 3SR7-A nrPDB 34 0.10 1N7K-A nrPDB 33 0.16 2P8U-A nrPDB 33 0.18 1MXS-A nrPDB 33 0.19 2ZRW-A nrPDB 33 0.23 1QAP-A nrPDB 33 0.23 3F4W-A nrPDB 33 0.26 1XI3-A nrPDB 32 0.32 5UE9-A nrPDB 32 0.43 5Z9Y-A nrPDB 32 0.48 1EP3-A nrPDB 32 0.51 1WV2-A nrPDB 32 0.52 3BIC-A nrPDB 32 0.54 6NKE-A nrPDB 32 0.57 4XBS-A nrPDB 32 0.60 1SZG-A nrPDB 31 0.65 3QH2-A nrPDB 31 0.66 1QCW-A nrPDB 31 0.70 5VIS-A nrPDB 31 0.86 2A1T-A nrPDB 31 0.94 6CTY-A nrPDB 31 0.97 4MM1-A nrPDB 31 0.97 1OFP-A nrPDB 30 1.1 4WY0-A nrPDB 30 1.4 3O07-A nrPDB 30 1.4 5KSD-A nrPDB 30 1.4 2ISS-A nrPDB 30 1.4 2ZBT-A nrPDB 30 1.5 1EUA-A nrPDB 30 1.5 5G1T-A nrPDB 30 1.6 2GGG-A nrPDB 30 1.6 1KA9-F nrPDB 30 1.7 3OIX-A nrPDB 30 1.7 4IQL-A nrPDB 30 1.7 6HYE-A nrPDB 30 1.8 4FQU-A nrPDB 30 1.9 4UTT-A nrPDB 30 1.9 2NV2-A nrPDB 29 2.5 1Y0E-A nrPDB 29 2.5 4X2R-A nrPDB 29 2.6 6DU6-A nrPDB 29 2.8 2HTM-A nrPDB 29 3.2 3W0K-A nrPDB 29 3.3 3MDE-A nrPDB 29 3.4 4HPN-A nrPDB 29 3.6 4HDR-A nrPDB 29 3.7 3W7D-A nrPDB 29 3.8 5UMF-A nrPDB 29 3.8 1X7D-A nrPDB 28 4.0 1JUE-A nrPDB 28 4.7 1PS9-A nrPDB 28 4.8 4EVZ-A nrPDB 28 4.9 1VH7-A nrPDB 28 4.9 6EI9-A nrPDB 28 5.2 4L4U-A nrPDB 28 5.5 1NY5-A nrPDB 28 5.5 3NL2-A nrPDB 28 5.6 4AXK-A nrPDB 28 5.7 5EY5-A nrPDB 28 5.9 5D2Y-A nrPDB 28 6.0 1ZY2-A nrPDB 28 6.2 3OA3-A nrPDB 28 6.5 5CSS-A nrPDB 28 7.2 2W6R-A nrPDB 28 8.0 2VEP-A nrPDB 28 8.1 4FMK-A nrPDB 28 8.6 4B2O-A nrPDB 27 9.1 1IYX-A nrPDB 27 9.3 5LNS-A nrPDB 27 9.6 4ADT-A nrPDB 27 9.8 3TI8-A nrPDB 27 9.9 >2BWG-A nrPDB Length = 367 Score = 458 bits (1178), Expect = e-129, Method: Composition-based stats. Identities = 276/345 (80%), Positives = 315/345 (91%) Query: 1 MPHIDNDVKLDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGT 60 MP ID D+KLDFKDVLLRPKRS+LKSR+EVDL R+F+FRNSKQTYSG+PII ANMDTVGT Sbjct: 23 MPRIDADLKLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGT 82 Query: 61 FEMAKVLCKFSLFTAVHKHYSLVQWQEFAGQNPDCLEHLAASSGTGSSDFEQLEQILEAI 120 FEMA V+ + S+FTA+HKHYSL W+ FA +P+CL+++A SSG+G +D E++ ILEA+ Sbjct: 83 FEMAAVMSQHSMFTAIHKHYSLDDWKLFATNHPECLQNVAVSSGSGQNDLEKMTSILEAV 142 Query: 121 PQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGI 180 PQVK+ICLDVANGYSEHFVEFVK VR +FP+HTIMAGNVVTGEMVEELILSGADIIKVG+ Sbjct: 143 PQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGV 202 Query: 181 GPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVM 240 GPGSVCTTR KTGVGYPQLSAV+ECAD+AHGLKGHIISDGGC+CPGDVAKAFGAGADFVM Sbjct: 203 GPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVM 262 Query: 241 LGGMLAGHSESGGELIERDGKKYKLFYGMSSEMAMKKYAGGVAEYRASEGKTVEVPFKGD 300 LGGM +GH+E GE+IER+G+K KLFYGMSS+ AM K+AGGVAEYRASEGKTVEVP+KGD Sbjct: 263 LGGMFSGHTECAGEVIERNGRKLKLFYGMSSDTAMNKHAGGVAEYRASEGKTVEVPYKGD 322 Query: 301 VEHTIRDILGGIRSTCTYVGAAKLKELSRRTTFIRVTQQVNPIFS 345 VE+TI DILGG+RSTCTYVGAAKLKELSRR TFIRVTQQ N +FS Sbjct: 323 VENTILDILGGLRSTCTYVGAAKLKELSRRATFIRVTQQHNTVFS 367 >2C6Q-A nrPDB Length = 351 Score = 444 bits (1143), Expect = e-125, Method: Composition-based stats. Identities = 332/333 (99%), Positives = 332/333 (99%) Query: 9 KLDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFEMAKVLC 68 LDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFEMAKVLC Sbjct: 19 SLDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFEMAKVLC 78 Query: 69 KFSLFTAVHKHYSLVQWQEFAGQNPDCLEHLAASSGTGSSDFEQLEQILEAIPQVKYICL 128 KFSLFTAVHKHYSLVQWQEFAGQNPDCLEHLAASSGTGSSDFEQLEQILEAIPQVKYICL Sbjct: 79 KFSLFTAVHKHYSLVQWQEFAGQNPDCLEHLAASSGTGSSDFEQLEQILEAIPQVKYICL 138 Query: 129 DVANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTT 188 DVANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTT Sbjct: 139 DVANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTT 198 Query: 189 RKKTGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGH 248 RKKTGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGH Sbjct: 199 RKKTGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGH 258 Query: 249 SESGGELIERDGKKYKLFYGMSSEMAMKKYAGGVAEYRASEGKTVEVPFKGDVEHTIRDI 308 SESGGELIERDGKKYKLFYGMSSEMAMKKYAGGVAEYRASEGKTVEVPFKGDVEHTIRDI Sbjct: 259 SESGGELIERDGKKYKLFYGMSSEMAMKKYAGGVAEYRASEGKTVEVPFKGDVEHTIRDI 318 Query: 309 LGGIRSTCTYVGAAKLKELSRRTTFIRVTQQVN 341 LGGIRSTCTYVGAAKLKELSRRTTFIRVTQQVN Sbjct: 319 LGGIRSTCTYVGAAKLKELSRRTTFIRVTQQVN 351 >5UQG-A nrPDB Length = 406 Score = 416 bits (1070), Expect = e-117, Method: Composition-based stats. Identities = 114/362 (31%), Positives = 182/362 (50%), Gaps = 35/362 (9%) Query: 4 IDNDVKLDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFEM 63 L F+DVLLRP S + + + +K +P+I+A MDTV Sbjct: 26 KIVKRALTFEDVLLRPGYSEVLPKE-----VKIHTKLTKNITLNMPLISAAMDTVTEHRA 80 Query: 64 AKVLCKFSLFTAVHKHYSL---------------------VQWQEFAGQNPDCLEHLAAS 102 A ++ + +HK+ + + +E+ N D L Sbjct: 81 AIMMARLGGLGVIHKNMDIASQVREVKRVKKSESGGIKDLKKRKEYPDANKDNFGRLRVG 140 Query: 103 SGTGSSDFEQLEQILEAIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTG 162 + G ++++ ++EA V + LD A+G+S+ ++ VK ++ ++P ++AGN+ T Sbjct: 141 AAIGVGQMDRVDALVEA--GVDVVVLDSAHGHSKGIIDTVKAIKAKYPNLDLIAGNIATA 198 Query: 163 EMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIISDGGC 222 + L +G D +KVGIGPGS+CTTR +GVG PQ+SA+ EC + A+ +I+DGG Sbjct: 199 AAAKALCEAGVDAVKVGIGPGSICTTRIVSGVGVPQISAIDECVEEANKFGVPVIADGGI 258 Query: 223 SCPGDVAKAFGAGADFVMLGGMLAGHSESGGELIERDGKKYKLFYGMSSEMAMKKY---- 278 GD+AKA GA VM+G +LAG ES GEL G++YK + GM S AM+K Sbjct: 259 KYSGDIAKALAVGASSVMIGSLLAGTDESPGELFTYQGRQYKSYRGMGSLGAMQKGSSDR 318 Query: 279 ---AGGVAEYRASEGKTVEVPFKGDVEHTIRDILGGIRSTCTYVGAAKLKELSRRTTFIR 335 G + EG VP+ G + + +LGG+RS+ YVGA +++ +R F+ Sbjct: 319 YFQQGTAQDKLVPEGIEGRVPYVGSIRSVVHQLLGGLRSSMGYVGAKDIEDFQKRAEFVE 378 Query: 336 VT 337 +T Sbjct: 379 IT 380 >4MJM-A nrPDB Length = 385 Score = 415 bits (1068), Expect = e-116, Method: Composition-based stats. Identities = 125/362 (34%), Positives = 184/362 (50%), Gaps = 35/362 (9%) Query: 4 IDNDVKLDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFEM 63 L F DVLL P +S + R T S+ +P+I+A MDTV +M Sbjct: 8 KFVKEGLTFDDVLLVPAKSDVLPREVSVKTV-----LSESLQLNIPLISAGMDTVTEADM 62 Query: 64 AKVLCKFSLFTAVHKHYSLVQWQE---------------------FAGQNPDCLEH--LA 100 A + + +HK+ S+ Q E F D + Sbjct: 63 AIAMARQGGLGIIHKNMSIEQQAEQVDKVKRSESGGIKDIEKVIEFPNSAKDKQGRLLVG 122 Query: 101 ASSGTGSSDFEQLEQILEAIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGNVV 160 A+ G + +++ +++A V I LD A+G+S+ ++ VK+VR ++P I+AGNV Sbjct: 123 AAVGVTADAMTRIDALVKA--SVDAIVLDTAHGHSQGVIDKVKEVRAKYPSLNIIAGNVA 180 Query: 161 TGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIISDG 220 T E + LI +GA+++KVGIGPGS+CTTR GVG PQL+AV +CA A +I+DG Sbjct: 181 TAEATKALIEAGANVVKVGIGPGSICTTRVVAGVGVPQLTAVYDCATEARKHGIPVIADG 240 Query: 221 GCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGELIERDGKKYKLFYGMSSEMAMKK--- 277 G GD+ KA AGA VMLG M AG +ES GE G+++K++ GM S AM+K Sbjct: 241 GIKYSGDMVKALAAGAHVVMLGSMFAGVAESPGETEIYQGRQFKVYRGMGSVGAMEKGSK 300 Query: 278 --YAGGVAEYRASEGKTVEVPFKGDVEHTIRDILGGIRSTCTYVGAAKLKELSRRTTFIR 335 Y + EG VP+KG + T+ ++GG+R+ Y GA L+ L FIR Sbjct: 301 DRYFQEGNKKLVPEGIEGRVPYKGPLADTVHQLVGGLRAGMGYCGAQDLEFLRENAQFIR 360 Query: 336 VT 337 ++ Sbjct: 361 MS 362 >4FEZ-A nrPDB Length = 388 Score = 413 bits (1062), Expect = e-116, Method: Composition-based stats. Identities = 112/364 (30%), Positives = 180/364 (49%), Gaps = 37/364 (10%) Query: 4 IDNDVKLDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFEM 63 L F DVLL P ST+ T R +K +P+++A+MDTV + Sbjct: 8 RIAKEALTFDDVLLVPAHSTVLP-----NTADLRTRLTKNIALNIPMVSASMDTVTEARL 62 Query: 64 AKVLCKFSLFTAVHKHYSLVQW-----------------------QEFAGQNPDCLEHLA 100 A L + +HK+ S+ Q + A ++ + Sbjct: 63 AIALAQEGGIGFIHKNMSIEQQAAQVHQVKIFESGGAKDFHKAESKPNACKDEQGRLRVG 122 Query: 101 ASSGTGSSDFEQLEQILEAIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGNVV 160 A+ G + E+++ ++EA V + +D ++G+SE ++ +++ R +P I+ GNV Sbjct: 123 AAVGAAPGNEERVKALVEA--GVDVLLIDSSHGHSEGVLQRIRETRAAYPHLEIIGGNVA 180 Query: 161 TGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIISDG 220 T E LI +G +KVGIGPGS+CTTR TGVG PQ++A+ + A A+ +I+DG Sbjct: 181 TAEGARALIEAGVSAVKVGIGPGSICTTRIVTGVGVPQITAIADAAGVANEYGIPVIADG 240 Query: 221 GCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGELIERDGKKYKLFYGMSSEMAMKKYAG 280 G GD++KA AGA VM+G M AG E+ GE+I G+ YK + GM S AM K + Sbjct: 241 GIRFSGDISKAIAAGASCVMVGSMFAGTEEAPGEVILYQGRSYKAYRGMGSLGAMSKGSS 300 Query: 281 -------GVAEYRASEGKTVEVPFKGDVEHTIRDILGGIRSTCTYVGAAKLKELSRRTTF 333 A+ EG + +KG ++ I +GG+RS G+A +++L + F Sbjct: 301 DRYFQTDNAADKLVPEGIEGRIAYKGHLKEIIHQQMGGLRSCMGLTGSATVEDLRTKAQF 360 Query: 334 IRVT 337 +R++ Sbjct: 361 VRIS 364 >1EEP-A nrPDB Length = 404 Score = 402 bits (1033), Expect = e-112, Method: Composition-based stats. Identities = 118/396 (29%), Positives = 190/396 (47%), Gaps = 65/396 (16%) Query: 1 MPHIDNDVKLDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGT 60 MP+ L F DV L P++S++ SEV L + +K +P +++ MDTV Sbjct: 1 MPNKITKEALTFDDVSLIPRKSSVLP-SEVSLKT----QLTKNISLNIPFLSSAMDTVTE 55 Query: 61 FEMAKVLCKFSLFTAVHKHYSLV------------QWQEFAGQNPDCLE----------- 97 +MA + K +HK+ S+ ++Q+ N D E Sbjct: 56 SQMAIAIAKEGGIGIIHKNMSIEAQRKEIEKVKTYKFQKTINTNGDTNEQKPEIFTAKQH 115 Query: 98 ---------------------------HLAASSGTGSSDFEQLEQILEAIPQVKYICLDV 130 + A+ E++E++++A V + +D Sbjct: 116 LEKSDAYKNAEHKEDFPNACKDLNNKLRVGAAVSIDIDTIERVEELVKAH--VDILVIDS 173 Query: 131 ANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTTRK 190 A+G+S +E +K ++ ++P ++AGN+VT E +LI GAD +KVGIGPGS+CTTR Sbjct: 174 AHGHSTRIIELIKKIKTKYPNLDLIAGNIVTKEAALDLISVGADCLKVGIGPGSICTTRI 233 Query: 191 KTGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSE 250 GVG PQ++A+ + +A + II+DGG GDV KA AGAD VM+G + AG E Sbjct: 234 VAGVGVPQITAICDVYEACNNTNICIIADGGIRFSGDVVKAIAAGADSVMIGNLFAGTKE 293 Query: 251 SGGELIERDGKKYKLFYGMSSEMAMKKYA--------GGVAEYRASEGKTVEVPFKGDVE 302 S E I +GKK+K + GM S AMK+ + + EG VP+ G ++ Sbjct: 294 SPSEEIIYNGKKFKSYVGMGSISAMKRGSKSRYFQLENNEPKKLVPEGIEGMVPYSGKLK 353 Query: 303 HTIRDILGGIRSTCTYVGAAKLKELSRRTTFIRVTQ 338 + + GG+ S Y+GAA + +L + F++++ Sbjct: 354 DILTQLKGGLMSGMGYLGAATISDLKINSKFVKISH 389 >3FFS-A nrPDB Length = 400 Score = 401 bits (1030), Expect = e-112, Method: Composition-based stats. Identities = 117/385 (30%), Positives = 185/385 (48%), Gaps = 56/385 (14%) Query: 1 MPHIDNDVKLDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGT 60 M + L F+D+LL P S + R S + +K +P+I++ MDTV Sbjct: 1 MGTKNIGKGLTFEDILLVPNYSEVLPRE-----VSLETKLTKNVSLKIPLISSAMDTVTE 55 Query: 61 FEMAKVLCKFSLFTAVHKHYSLVQW----------------------------------- 85 MA + + +HK+ + Sbjct: 56 HLMAVGMARLGGIGIIHKNMDMESQVNEVLKVKNWISNLEKNESTPDQNLDKESTDGKDT 115 Query: 86 ------QEFAGQNPDCLEHLAASSGTGSSDFEQLEQILEAIPQVKYICLDVANGYSEHFV 139 ++ +N D L + G ++ E+ + ++EA V I LD A+G+S + + Sbjct: 116 KSNNNIDAYSNENLDNKGRLRVGAAIGVNEIERAKLLVEA--GVDVIVLDSAHGHSLNII 173 Query: 140 EFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQL 199 +K+++ + ++ GNVVT E +ELI +GAD IKVGIGPGS+CTTR GVG PQ+ Sbjct: 174 RTLKEIKSKM-NIDVIVGNVVTEEATKELIENGADGIKVGIGPGSICTTRIVAGVGVPQI 232 Query: 200 SAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGELIERD 259 +A+ +C+ A II+DGG GD+ KA GA VM+G +LAG ES GE Sbjct: 233 TAIEKCSSVASKFGIPIIADGGIRYSGDIGKALAVGASSVMIGSILAGTEESPGEKELIG 292 Query: 260 GKKYKLFYGMSSEMAMKKYAGG--VAEYR-----ASEGKTVEVPFKGDVEHTIRDILGGI 312 YK + GM S AMK +G E R EG V +KG++E + ++GG+ Sbjct: 293 DTVYKYYRGMGSVGAMKSGSGDRYFQEKRPENKMVPEGIEGRVKYKGEMEGVVYQLVGGL 352 Query: 313 RSTCTYVGAAKLKELSRRTTFIRVT 337 RS Y+G+A ++EL ++++++ +T Sbjct: 353 RSCMGYLGSASIEELWKKSSYVEIT 377 >4QJ1-A nrPDB Length = 361 Score = 399 bits (1026), Expect = e-112, Method: Composition-based stats. Identities = 115/344 (33%), Positives = 182/344 (52%), Gaps = 16/344 (4%) Query: 1 MPHIDNDVKLDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGT 60 M + L F+D+LL P S + R S + +K +P+I++ MDTV Sbjct: 4 MGTKNIGKGLTFEDILLVPNYSEVLPRE-----VSLETKLTKNVSLKIPLISSAMDTVTE 58 Query: 61 FEMAKVLCKFSLFTAVHKHYSLVQWQEFAGQNPDCLEHLAASSGTGSSDFEQLEQILEAI 120 MA + + +HK+ + + + L + G ++ E+ + ++EA Sbjct: 59 HLMAVGMARLGGIGIIHKNMDMESQVNEVLKVKNS-GGLRVGAAIGVNEIERAKLLVEA- 116 Query: 121 PQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGI 180 V I LD A+G+S + + +K+++ + ++ GNVVT E +ELI +GAD IKVGI Sbjct: 117 -GVDVIVLDSAHGHSLNIIRTLKEIKSKM-NIDVIVGNVVTEEATKELIENGADGIKVGI 174 Query: 181 GPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVM 240 GPGS+CTTR GVG PQ++A+ +C+ A II+DGG GD+ KA GA VM Sbjct: 175 GPGSICTTRIVAGVGVPQITAIEKCSSVASKFGIPIIADGGIRYSGDIGKALAVGASSVM 234 Query: 241 LGGMLAGHSESGGELIERDGKKYKLFYGMSSEMAMKKYAGG--VAEYR-----ASEGKTV 293 +G +LAG ES GE YK + GM S AMK +G E R EG Sbjct: 235 IGSILAGTEESPGEKELIGDTVYKYYRGMGSVGAMKSGSGDRYFQEKRPENKMVPEGIEG 294 Query: 294 EVPFKGDVEHTIRDILGGIRSTCTYVGAAKLKELSRRTTFIRVT 337 V +KG++E + ++GG+RS Y+G+A ++EL ++++++ +T Sbjct: 295 RVKYKGEMEGVVYQLVGGLRSCMGYLGSASIEELWKKSSYVEIT 338 >4XTI-A nrPDB Length = 413 Score = 389 bits (999), Expect = e-108, Method: Composition-based stats. Identities = 103/352 (29%), Positives = 164/352 (46%), Gaps = 35/352 (9%) Query: 9 KLDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFEMAKVLC 68 L + D L+ P + S V S R +K+ P +++ MDTV +MA + Sbjct: 38 GLTYNDFLVLPGKIDFPSSEVV-----LSSRLTKKITLNAPFVSSPMDTVTEADMAIHMA 92 Query: 69 KFSLFTAVHKHYSLVQWQEF----------------AGQNPDCLEHL-AASSGTGSSDFE 111 +H + + + E A ++ D + L A+ GT +D + Sbjct: 93 LLGGIGIIHHNCTAEEQAEMVRRVKKYENGSQDGPLASKSADTKQLLCGAAIGTIDADRQ 152 Query: 112 QLEQILEAIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILS 171 +L ++EA + + LD + G S + +K +++ FP ++AGNVVT E LI + Sbjct: 153 RLAMLVEA--GLDVVVLDSSQGNSVFQINMIKWIKETFPDLQVIAGNVVTREQAASLIHA 210 Query: 172 GADIIKVGIGPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKA 231 GAD +++G+G GS+C T++ G PQ +AV A+ I+DGG G + KA Sbjct: 211 GADGLRIGMGSGSICITQEVMACGRPQGTAVYNVTQFANQFGVPCIADGGVQNIGHITKA 270 Query: 232 FGAGADFVMLGGMLAGHSESGGELIERDGKKYKLFYGMSSEMAMKK-----------YAG 280 GA VM+GGMLAG +ES GE RDGK+ K + GM S AM+K Y Sbjct: 271 IALGASTVMMGGMLAGTTESPGEYFFRDGKRLKTYRGMGSIDAMQKTDVKGNAATSRYFS 330 Query: 281 GVAEYRASEGKTVEVPFKGDVEHTIRDILGGIRSTCTYVGAAKLKELSRRTT 332 + ++G T V KG ++ I + G++ +C +G L E + Sbjct: 331 ESDKVLVAQGVTGSVIDKGSIKKYIPYLYNGLQHSCQDIGVRSLVEFREKVD 382 >3R2G-A nrPDB Length = 361 Score = 378 bits (971), Expect = e-105, Method: Composition-based stats. Identities = 120/336 (35%), Positives = 188/336 (55%), Gaps = 13/336 (3%) Query: 4 IDNDVKLDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFEM 63 + D + F DVLL P + +SR V+ T + + +P+I+ANMDT+ M Sbjct: 2 VMTDQAITFDDVLLVPSYNHHESRRVVETTSTDRL---GKLTLNLPVISANMDTITESNM 58 Query: 64 AKVLCKFSLFTAVHKHYSLVQWQEFAGQNPDCLEHLAASSGTGSSDFEQLEQILEAIPQV 123 A + A+H+ ++ + + + C + S G ++ ++ E + +A Sbjct: 59 ANFMHSKGAMGALHRFMTIEENIQ---EFKKCKGPVFVSVGCTENELQRAEALRDA--GA 113 Query: 124 KYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPG 183 + C+DVA+ ++++ + +K +R+ IMAGNV T + L GADIIK GIG G Sbjct: 114 DFFCVDVAHAHAKYVGKTLKSLRQLLGSRCIMAGNVATYAGADYLASCGADIIKAGIGGG 173 Query: 184 SVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGG 243 SVC+TR KTG G P L+ + +C+ A I++DGG GD+ KA GADFVM+GG Sbjct: 174 SVCSTRIKTGFGVPMLTCIQDCSRADR----SIVADGGIKTSGDIVKALAFGADFVMIGG 229 Query: 244 MLAGHSESGGELIER-DGKKYKLFYGMSSEMAMKKYAGGVAEYRASEGKTVEVPFKGDVE 302 MLAG + + GE+ ++ DG K K + GM+S A + + G + E++ +EG EVPFK + + Sbjct: 230 MLAGSAPTPGEVFQKDDGSKVKRYRGMASREAQEAFLGQMHEWKTAEGVATEVPFKENPD 289 Query: 303 HTIRDILGGIRSTCTYVGAAKLKELSRRTTFIRVTQ 338 I DI+GG+RS TY GA + EL R+ ++ VTQ Sbjct: 290 GIIADIIGGLRSGLTYAGADSISELQRKLNYVIVTQ 325 >5AHL-A nrPDB Length = 400 Score = 366 bits (939), Expect = e-101, Method: Composition-based stats. Identities = 113/361 (31%), Positives = 177/361 (49%), Gaps = 34/361 (9%) Query: 4 IDNDVKLDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFEM 63 + L F DVLL P S + + S R ++ +P+++A MDTV + Sbjct: 23 RISQEALTFDDVLLIPGYSEVLPKD-----VSLKTRLTRGIELNIPLVSAAMDTVTEARL 77 Query: 64 AKVLCKFSLFTAVHKHYSLVQW-----------------QEFAGQNPDCLEHLAASSGTG 106 A + + +HK+ + Q A ++ + A+ GTG Sbjct: 78 AIAMAQEGGIGIIHKNMGIEQQAAEVRKVKKHETAKAKTYPLASKDEQGRLRVGAAVGTG 137 Query: 107 SSDFEQLEQILEAIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVE 166 + E++ ++ A V + A+G+S+ +E V+ V++ FP ++ GN+ T E + Sbjct: 138 ADTGERVAALVAAGVDVVVVD--TAHGHSKGVIERVRWVKQTFPDVQVIGGNIATAEAAK 195 Query: 167 ELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPG 226 L +GAD +KVGIGPGS+CTTR GVG PQ+SA+ A A G +I+DGG G Sbjct: 196 ALAEAGADAVKVGIGPGSICTTRIVAGVGVPQISAIANVAAALEGTGVPLIADGGIRFSG 255 Query: 227 DVAKAFGAGADFVMLGGMLAGHSESGGELIERDGKKYKLFYGMSSEMAMKKYAGGV---- 282 D+AKA AGA VM+G M AG E+ GE+ G+ YK + GM S AM G Sbjct: 256 DLAKAMVAGAYCVMMGSMFAGTEEAPGEIELFQGRSYKSYRGMGSLGAMSGSQGSSDRYF 315 Query: 283 ------AEYRASEGKTVEVPFKGDVEHTIRDILGGIRSTCTYVGAAKLKELSRRTTFIRV 336 AE EG VP+KG + + ++GG+R+ Y G+A ++++ + F+R+ Sbjct: 316 QDASAGAEKLVPEGIEGRVPYKGALSAIVHQLMGGLRAAMGYTGSADIQQMRTQPQFVRI 375 Query: 337 T 337 T Sbjct: 376 T 376 >5UPU-A nrPDB Length = 407 Score = 364 bits (934), Expect = e-101, Method: Composition-based stats. Identities = 107/352 (30%), Positives = 173/352 (49%), Gaps = 24/352 (6%) Query: 2 PHIDNDVKLDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTF 61 PH + L F DVLL P S + V T S + +K+ VP++++ MDTV Sbjct: 40 PHKVAMLGLTFDDVLLLPAASDV-----VPATADTSSQLTKKIRLKVPLVSSAMDTVTES 94 Query: 62 EMAKVLCKFSLFTAVHKHYSLVQWQEFAGQNPDCLEH-LAASSGTGSSDFEQLEQILEAI 120 MA + + +H++ + + + A+ G G + + +++A Sbjct: 95 RMAIAMARAGGMGVLHRNLPVAEQAGQVEMVKRSGGLLVGAAVGVGGDAWVRAMMLVDA- 153 Query: 121 PQVKYICLDVANGYSEHFVEFVKDVRKRFPQHT-IMAGNVVTGEMVEELILSGADIIKVG 179 V + +D A+ ++ ++ V ++ ++ GNV T L+ +GAD +KVG Sbjct: 154 -GVDVLVVDTAHAHNRLVLDMVGKLKSEVGDRVEVVGGNVATRSAAAALVDAGADAVKVG 212 Query: 180 IGPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFV 239 +GPGS+CTTR GVG PQ++A++E A +I+DGG GD+AKA AGA Sbjct: 213 VGPGSICTTRVVAGVGAPQITAILEAVAACRPAGVPVIADGGLQYSGDIAKALAAGASTA 272 Query: 240 MLGGMLAGHSESGGELIERDGKKYKLFYGMSSEMAMKKYAGGVA--------------EY 285 MLG +LAG +E+ GELI +GK+YK + GM S AM+ G + + Sbjct: 273 MLGSLLAGTAEAPGELIFVNGKQYKSYRGMGSLGAMRGRGGATSYSKDRYFADDALSEDK 332 Query: 286 RASEGKTVEVPFKGDVEHTIRDILGGIRSTCTYVGAAKLKELSRRTTFIRVT 337 EG VPF+G + I + GG+R+ Y G+ ++ L + F+R+T Sbjct: 333 LVPEGIEGRVPFRGPLSSVIHQLTGGLRAAMGYTGSPTIEVLQ-QAQFVRIT 383 >3TSB-A nrPDB Length = 511 Score = 347 bits (889), Expect = 5e-96, Method: Composition-based stats. Identities = 101/264 (38%), Positives = 150/264 (56%), Gaps = 9/264 (3%) Query: 81 SLVQWQEFAGQNPDCLEH--LAASSGTGSSDFEQLEQILEAIPQVKYICLDVANGYSEHF 138 + + EF D + A+ G + +++ +++A V I LD A+G+S+ Sbjct: 227 DIEKVIEFPNSAKDKQGRLLVGAAVGVTADAMTRIDALVKA--SVDAIVLDTAHGHSQGV 284 Query: 139 VEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQ 198 ++ VK+VR ++P I+AGNV T E + LI +GA+++KVGIGPGS+CTTR GVG PQ Sbjct: 285 IDKVKEVRAKYPSLNIIAGNVATAEATKALIEAGANVVKVGIGPGSICTTRVVAGVGVPQ 344 Query: 199 LSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGELIER 258 L+AV +CA A +I+DGG GD+ KA AGA VMLG M AG +ES GE Sbjct: 345 LTAVYDCATEARKHGIPVIADGGIKYSGDMVKALAAGAHVVMLGSMFAGVAESPGETEIY 404 Query: 259 DGKKYKLFYGMSSEMAMKK-----YAGGVAEYRASEGKTVEVPFKGDVEHTIRDILGGIR 313 G+++K++ GM S AM+K Y + EG VP+KG + T+ ++GG+R Sbjct: 405 QGRQFKVYRGMGSVGAMEKGSKDRYFQEGNKKLVPEGIEGRVPYKGPLADTVHQLVGGLR 464 Query: 314 STCTYVGAAKLKELSRRTTFIRVT 337 + Y GA L+ L FIR++ Sbjct: 465 AGMGYCGAQDLEFLRENAQFIRMS 488 Score = 101 bits (251), Expect = 5e-22, Method: Composition-based stats. Identities = 25/96 (26%), Positives = 39/96 (40%), Gaps = 5/96 (5%) Query: 4 IDNDVKLDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFEM 63 L F DVLL P +S + R T S+ +P+I+A MDTV +M Sbjct: 29 KFVKEGLTFDDVLLVPAKSDVLPREVSVKTV-----LSESLQLNIPLISAGMDTVTEADM 83 Query: 64 AKVLCKFSLFTAVHKHYSLVQWQEFAGQNPDCLEHL 99 A + + +HK+ S+ Q E + + Sbjct: 84 AIAMARQGGLGIIHKNMSIEQQAEQVDKVKRSESGV 119 >1VRD-A nrPDB Length = 494 Score = 345 bits (886), Expect = 1e-95, Method: Composition-based stats. Identities = 108/331 (32%), Positives = 168/331 (50%), Gaps = 19/331 (5%) Query: 24 LKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFEMAKV----------LCKFSLF 73 L + +V ++ S + +I A D + + K + Sbjct: 141 LLTNRDVRFEKNLSKKIKDLMTPREKLIVAPPDISLEKAKEILHQHRIEKLPLVSKDNKL 200 Query: 74 TAVHKHYSLVQWQEFAGQNPDCLEH--LAASSGTGSSDFEQLEQILEAIPQVKYICLDVA 131 + ++ E D + A+ GT E++E++++A V I +D A Sbjct: 201 VGLITIKDIMSVIEHPNAARDEKGRLLVGAAVGTSPETMERVEKLVKA--GVDVIVIDTA 258 Query: 132 NGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTTRKK 191 +G+S +E ++ ++ +P ++AGNV T E E LI +GAD +KVG+GPGS+CTTR Sbjct: 259 HGHSRRVIETLEMIKADYPDLPVVAGNVATPEGTEALIKAGADAVKVGVGPGSICTTRVV 318 Query: 192 TGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSES 251 GVG PQL+AVMEC++ A II+DGG GD+ KA AGA+ VM+G + AG E+ Sbjct: 319 AGVGVPQLTAVMECSEVARKYDVPIIADGGIRYSGDIVKALAAGAESVMVGSIFAGTEEA 378 Query: 252 GGELIERDGKKYKLFYGMSSEMAMK-----KYAGGVAEYRASEGKTVEVPFKGDVEHTIR 306 GE I G+KYK + GM S AM+ +Y EG VP+KG V+ + Sbjct: 379 PGETILYQGRKYKAYRGMGSLGAMRSGSADRYGQEGENKFVPEGIEGMVPYKGTVKDVVH 438 Query: 307 DILGGIRSTCTYVGAAKLKELSRRTTFIRVT 337 ++GG+RS Y+GA +KEL + F+++T Sbjct: 439 QLVGGLRSGMGYIGARTIKELQEKAVFVKIT 469 Score = 88.2 bits (217), Expect = 6e-18, Method: Composition-based stats. Identities = 21/89 (23%), Positives = 36/89 (40%), Gaps = 5/89 (5%) Query: 7 DVKLDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFEMAKV 66 L F DVLL P+ S + + R ++Q +P+++A MDTV +AK Sbjct: 14 KEALTFDDVLLVPQYSEVLPKD-----VKIDTRLTRQIRINIPLVSAAMDTVTEAALAKA 68 Query: 67 LCKFSLFTAVHKHYSLVQWQEFAGQNPDC 95 L + +HK+ + + Sbjct: 69 LAREGGIGIIHKNLTPDEQARQVSIVKKT 97 >4FXS-A nrPDB Length = 496 Score = 338 bits (867), Expect = 2e-93, Method: Composition-based stats. Identities = 89/267 (33%), Positives = 147/267 (55%), Gaps = 9/267 (3%) Query: 78 KHYSLVQWQEFAGQNPDCLEHLAASSGTGSSDFEQLEQILEAIPQVKYICLDVANGYSEH 137 K + + + A ++ + A+ G + E+++ ++EA V + +D ++G+SE Sbjct: 201 KDFHKAESKPNACKDEQGRLRVGAAVGAAPGNEERVKALVEA--GVDVLLIDSSHGHSEG 258 Query: 138 FVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYP 197 ++ +++ R +P I+ GNV T E LI +G +KVGIGPGS+CTTR TGVG P Sbjct: 259 VLQRIRETRAAYPHLEIIGGNVATAEGARALIEAGVSAVKVGIGPGSICTTRIVTGVGVP 318 Query: 198 QLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGELIE 257 Q++A+ + A A+ +I+DGG GD++KA AGA VM+G M AG E+ GE+I Sbjct: 319 QITAIADAAGVANEYGIPVIADGGIRFSGDISKAIAAGASCVMVGSMFAGTEEAPGEVIL 378 Query: 258 RDGKKYKLFYGMSSEMAMKKYAG-------GVAEYRASEGKTVEVPFKGDVEHTIRDILG 310 G+ YK + GM S AM K + A+ EG + +KG ++ I +G Sbjct: 379 YQGRSYKAYRGMGSLGAMSKGSSDRYFQTDNAADKLVPEGIEGRIAYKGHLKEIIHQQMG 438 Query: 311 GIRSTCTYVGAAKLKELSRRTTFIRVT 337 G+RS G+A +++L + F+R++ Sbjct: 439 GLRSCMGLTGSATVEDLRTKAQFVRIS 465 Score = 100 bits (248), Expect = 1e-21, Method: Composition-based stats. Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 5/83 (6%) Query: 4 IDNDVKLDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFEM 63 L F DVLL P ST+ T R +K +P+++A+MDTV + Sbjct: 5 RIAKEALTFDDVLLVPAHSTVLP-----NTADLRTRLTKNIALNIPMVSASMDTVTEARL 59 Query: 64 AKVLCKFSLFTAVHKHYSLVQWQ 86 A L + +HK+ S+ Q Sbjct: 60 AIALAQEGGIGFIHKNMSIEQQA 82 >1YPF-A nrPDB Length = 336 Score = 335 bits (858), Expect = 2e-92, Method: Composition-based stats. Identities = 118/343 (34%), Positives = 180/343 (52%), Gaps = 32/343 (9%) Query: 10 LDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFEMAKVLCK 69 D++D+ L P + + SRSE D T + K +P++ ANM T+ +A L + Sbjct: 14 FDYEDIQLIPAKCIVNSRSECDTTVTLGKHKFK-----LPVVPANMQTIIDERIATYLAE 68 Query: 70 FSLFTAVH-----KHYSLVQWQEFAGQNPDCLEHLAASSGTGSSDFEQLEQILEAIPQVK 124 + F +H K S ++ + G + S G ++E ++Q+ + Sbjct: 69 NNYFYIMHRFQPEKRISFIRDMQSRGLIA------SISVGVKEDEYEFVQQLAAEHLTPE 122 Query: 125 YICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGS 184 YI +D+A+G+S + ++ ++K P+ ++AGNV T E V EL +GAD KVGIGPG Sbjct: 123 YITIDIAHGHSNAVINMIQHIKKHLPESFVIAGNVGTPEAVRELENAGADATKVGIGPGK 182 Query: 185 VCTTRKKTGVGY--PQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLG 242 VC T+ KTG G QL+A+ CA AA II+DGG GDVAK+ GA VM+G Sbjct: 183 VCITKIKTGFGTGGWQLAALRWCAKAASK---PIIADGGIRTNGDVAKSIRFGATMVMIG 239 Query: 243 GMLAGHSESGGELIERDGKKYKLFYGMSSEMAMKKYAGGVAEYRASEGKTVEVPFKGDVE 302 + AGH ES GE IE+DGK YK ++G +SE E + EGK + V KG +E Sbjct: 240 SLFAGHEESPGETIEKDGKLYKEYFGSASEFQ-------KGEKKNVEGKKMFVEHKGSLE 292 Query: 303 HTIRDILGGIRSTCTYVGAAKLKELSRRTTFIRVTQQVNPIFS 345 T+ ++ ++S+ +Y G KL + ++ V N IF+ Sbjct: 293 DTLIEMEQDLQSSISYAGGTKLDSIRT-VDYVVVK---NSIFN 331 >1ZFJ-A nrPDB Length = 491 Score = 333 bits (855), Expect = 6e-92, Method: Composition-based stats. Identities = 100/267 (37%), Positives = 139/267 (52%), Gaps = 12/267 (4%) Query: 81 SLVQWQEFAGQNPDCLEH--LAASSGTGSSDFEQLEQILEAIPQVKYICLDVANGYSEHF 138 + + EF D +AA+ G S FE+ E + EA I +D A+G+S Sbjct: 204 DIEKVIEFPHAAKDEFGRLLVAAAVGVTSDTFERAEALFEA--GADAIVIDTAHGHSAGV 261 Query: 139 VEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQ 198 + + ++R FP T++AGN+ T E L +G D++KVGIGPGS+CTTR GVG PQ Sbjct: 262 LRKIAEIRAHFPNRTLIAGNIATAEGARALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQ 321 Query: 199 LSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGELIER 258 ++A+ + A A II+DGG GD+ KA AG + VMLG M AG E+ GE Sbjct: 322 VTAIYDAAAVAREYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIY 381 Query: 259 DGKKYKLFYGMSSEMAMKKYAG--------GVAEYRASEGKTVEVPFKGDVEHTIRDILG 310 G+KYK + GM S AMKK + A EG V +KG + +LG Sbjct: 382 QGRKYKTYRGMGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAASDIVFQMLG 441 Query: 311 GIRSTCTYVGAAKLKELSRRTTFIRVT 337 GIRS YVGA ++EL F+ ++ Sbjct: 442 GIRSGMGYVGAGDIQELHENAQFVEMS 468 Score = 86.2 bits (212), Expect = 2e-17, Method: Composition-based stats. Identities = 21/93 (22%), Positives = 34/93 (36%), Gaps = 5/93 (5%) Query: 7 DVKLDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFEMAKV 66 F DVLL P S + + + +PII A MDTV +MA Sbjct: 9 KKGYTFDDVLLIPAESHVLPNE-----VDLKTKLADNLTLNIPIITAAMDTVTGSKMAIA 63 Query: 67 LCKFSLFTAVHKHYSLVQWQEFAGQNPDCLEHL 99 + + +HK+ S+ + E + + Sbjct: 64 IARAGGLGVIHKNMSITEQAEEVRKVKRSENGV 96 >6I0M-A nrPDB Length = 517 Score = 318 bits (815), Expect = 3e-87, Method: Composition-based stats. Identities = 74/263 (28%), Positives = 131/263 (49%), Gaps = 7/263 (2%) Query: 73 FTAVHKHYSLVQWQEFAGQNPDCLEHLAASSGTGSSDFEQLEQILEAIPQVKYICLDVAN 132 A+ L + +++ + D + L + G+ + ++ L A V + LD + Sbjct: 221 LVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQ 280 Query: 133 GYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTTRKKT 192 G S + +K ++ ++P ++ GNVVT + LI +G D ++VG+G GS+C T++ Sbjct: 281 GNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVL 340 Query: 193 GVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESG 252 G PQ +AV + ++ A +I+DGG G +AKA GA VM+G +LA +E+ Sbjct: 341 ACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAP 400 Query: 253 GELIERDGKKYKLFYGMSSEMAMKKYAGGVAEY-------RASEGKTVEVPFKGDVEHTI 305 GE DG + K + GM S AM K+ Y + ++G + V KG + + Sbjct: 401 GEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFV 460 Query: 306 RDILGGIRSTCTYVGAAKLKELS 328 ++ GI+ +C +GA L ++ Sbjct: 461 PYLIAGIQHSCQDIGAKSLTQVR 483 Score = 79.7 bits (195), Expect = 2e-15, Method: Composition-based stats. Identities = 17/113 (15%), Positives = 37/113 (32%), Gaps = 6/113 (5%) Query: 9 KLDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFEMAKVLC 68 L + D L+ P + + +K+ P++++ MDTV MA + Sbjct: 32 GLTYNDFLILPGYIDFTADQ-----VDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMA 86 Query: 69 KFSLFTAVHKHYSLVQWQEFAGQNPDCLEHLAASSGTGSSDFEQLEQILEAIP 121 +H + + + E + S +++ + EA Sbjct: 87 LTGGIGFIHHNCTPEFQANEVRKVKK-YEQGFITDPVVLSPKDRVRDVFEAKA 138 >4Z87-A nrPDB Length = 525 Score = 317 bits (812), Expect = 5e-87, Method: Composition-based stats. Identities = 86/261 (32%), Positives = 133/261 (50%), Gaps = 14/261 (5%) Query: 84 QWQEFAGQNPDCLEHL-AASSGTGSSDFEQLEQILEAIPQVKYICLDVANGYSEHFVEFV 142 Q A ++ D + L A+ GT +D ++L ++EA + + LD + G S + + Sbjct: 236 QSYPLASKSADTKQLLCGAAIGTIDADRQRLAMLVEA--GLDVVVLDSSQGNSVFQINMI 293 Query: 143 KDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAV 202 K +++ FP ++AGNVVT E LI +GAD +++G+G GS+C T++ G PQ +AV Sbjct: 294 KWIKETFPDLQVIAGNVVTREQAASLIHAGADGLRIGMGSGSICITQEVMACGRPQGTAV 353 Query: 203 MECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGELIERDGKK 262 A+ I+DGG G + KA GA VM+GGMLAG +ES GE RDGK+ Sbjct: 354 YNVTQFANQFGVPCIADGGVQNIGHITKAIALGASTVMMGGMLAGTTESPGEYFFRDGKR 413 Query: 263 YKLFYGMSSEMAMKK-----------YAGGVAEYRASEGKTVEVPFKGDVEHTIRDILGG 311 K + GM S AM+K Y + ++G T V KG ++ I + G Sbjct: 414 LKTYRGMGSIDAMQKTDVKGNAATSRYFSESDKVLVAQGVTGSVIDKGSIKKYIPYLYNG 473 Query: 312 IRSTCTYVGAAKLKELSRRTT 332 ++ +C +G L E + Sbjct: 474 LQHSCQDIGVRSLVEFREKVD 494 Score = 95.1 bits (235), Expect = 4e-20, Method: Composition-based stats. Identities = 20/101 (19%), Positives = 36/101 (35%), Gaps = 6/101 (5%) Query: 9 KLDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFEMAKVLC 68 L + D L+ P + S V S R +K+ P +++ MDTV +MA + Sbjct: 38 GLTYNDFLVLPGKIDFPSSEVV-----LSSRLTKKITLNAPFVSSPMDTVTEADMAIHMA 92 Query: 69 KFSLFTAVHKHYSLVQWQEFAGQNPD-CLEHLAASSGTGSS 108 +H + + + E + + A G Sbjct: 93 LLGGIGIIHHNCTAEEQAEMVRRVKKYENGFINAPVVVGPD 133 >1JCN-A nrPDB Length = 514 Score = 313 bits (802), Expect = 7e-86, Method: Composition-based stats. Identities = 80/266 (30%), Positives = 134/266 (50%), Gaps = 11/266 (4%) Query: 73 FTAVHKHYSLVQWQEFAGQNPDCLEHL--AASSGTGSSDFEQLEQILEAIPQVKYICLDV 130 A+ L + +++ + D + L A+ GT D +L+ + +A V I LD Sbjct: 218 LVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTREDDKYRLDLLTQA--GVDVIVLDS 275 Query: 131 ANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTTRK 190 + G S + + V +++++P ++ GNVVT + LI +G D ++VG+G GS+C T++ Sbjct: 276 SQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQE 335 Query: 191 KTGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSE 250 G PQ +AV + A+ A II+DGG G V KA GA VM+G +LA +E Sbjct: 336 VMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVVKALALGASTVMMGSLLAATTE 395 Query: 251 SGGELIERDGKKYKLFYGMSSEMAMKKYAGGVAEY-------RASEGKTVEVPFKGDVEH 303 + GE DG + K + GM S AM+K + Y + ++G + + KG ++ Sbjct: 396 APGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQK 455 Query: 304 TIRDILGGIRSTCTYVGAAKLKELSR 329 + ++ GI+ C +GA L L Sbjct: 456 FVPYLIAGIQHGCQDIGARSLSVLRS 481 Score = 76.2 bits (186), Expect = 2e-14, Method: Composition-based stats. Identities = 18/88 (20%), Positives = 36/88 (40%), Gaps = 5/88 (5%) Query: 10 LDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFEMAKVLCK 69 L + D L+ P + EVDLT + + ++ P+I++ MDTV +MA + Sbjct: 30 LTYNDFLILPGFIDFIA-DEVDLTSALT----RKITLKTPLISSPMDTVTEADMAIAMAL 84 Query: 70 FSLFTAVHKHYSLVQWQEFAGQNPDCLE 97 +H + + + + + Sbjct: 85 MGGIGFIHHNCTPEFQANEVRKVKNFEQ 112 >4AF0-B nrPDB Length = 556 Score = 299 bits (766), Expect = 1e-81, Method: Composition-based stats. Identities = 83/269 (30%), Positives = 139/269 (51%), Gaps = 25/269 (9%) Query: 84 QWQEFAGQNPDCLE-HLAASSGTGSSDFEQLEQILEAIPQVKYICLDVANGYSEHFVEFV 142 Q +A + P+ + + A+ GT D ++L+ + EA + + LD + G S + +EF+ Sbjct: 256 QNYPYASKVPESKQLYCGAAIGTRPGDKDRLKLLAEA--GLDVVVLDSSQGNSVYQIEFI 313 Query: 143 KDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAV 202 K +++ +P+ ++AGNVVT E +LI +GAD +++G+G GS+C T++ VG PQ +AV Sbjct: 314 KWIKQTYPKIDVIAGNVVTREQAAQLIAAGADGLRIGMGSGSICITQEVMAVGRPQGTAV 373 Query: 203 MECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGELIERDGKK 262 A+ A I+DGG G +AKA GA VM+GG+LAG +ES GE +GK+ Sbjct: 374 YAVAEFASRFGIPCIADGGIGNIGHIAKALALGASAVMMGGLLAGTTESPGEYFYHEGKR 433 Query: 263 YKLFYGMSSEMAMKKYAGGVAEY----------------------RASEGKTVEVPFKGD 300 K++ GM S AM+ G A + ++G + +V KG Sbjct: 434 VKVYRGMGSIEAMEHTQRGSASGKRSILGLDNAATARYFSEADAVKVAQGVSGDVADKGS 493 Query: 301 VEHTIRDILGGIRSTCTYVGAAKLKELSR 329 + + + G++ + G + EL Sbjct: 494 INKFVPYLFTGLQHSLQDAGIKSVSELHS 522 Score = 82.4 bits (202), Expect = 3e-16, Method: Composition-based stats. Identities = 16/86 (18%), Positives = 28/86 (32%), Gaps = 5/86 (5%) Query: 9 KLDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFEMAKVLC 68 L + D L+ P + S + +K P +++ MDTV MA L Sbjct: 59 GLTYNDFLVLPGHINFPASD-----VSLQSKATKNIVLNTPFLSSPMDTVTEDRMAIALA 113 Query: 69 KFSLFTAVHKHYSLVQWQEFAGQNPD 94 +H + S + + Sbjct: 114 LHGGLGIIHHNCSAEEQAAMVRRVKK 139 >2CU0-A nrPDB Length = 486 Score = 296 bits (757), Expect = 1e-80, Method: Composition-based stats. Identities = 92/278 (33%), Positives = 149/278 (53%), Gaps = 13/278 (4%) Query: 69 KFSLFTAVHKHYSLVQWQEFAGQNPDCLEHLAASSGTGSSDFEQLEQILEAIPQVKYICL 128 + + LV +++ D L ++ D ++ ++ +A V I + Sbjct: 189 ERGKLVGLITMSDLVARKKYKNAVRDENGELLVAAAVSPFDIKRAIELDKA--GVDVIVV 246 Query: 129 DVANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTT 188 D A+ ++ ++ +K++R++ I+ GN+ + V++L AD +KVGIGPGS+CTT Sbjct: 247 DTAHAHNLKAIKSMKEMRQKVDADFIV-GNIANPKAVDDLTF--ADAVKVGIGPGSICTT 303 Query: 189 RKKTGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGH 248 R GVG PQ++AV AD A ++I+DGG GD+ KA AGAD VMLG +LAG Sbjct: 304 RIVAGVGVPQITAVAMVADRAQEYGLYVIADGGIRYSGDIVKAIAAGADAVMLGNLLAGT 363 Query: 249 SESGGELIERDGKKYKLFYGMSSEMAMKK------YAGGVAEYR--ASEGKTVEVPFKGD 300 E+ G+ + +G+KYK + GM S AM K Y GG + R EG VP++G Sbjct: 364 KEAPGKEVIINGRKYKQYRGMGSLGAMMKGGAERYYQGGYMKTRKFVPEGVEGVVPYRGT 423 Query: 301 VEHTIRDILGGIRSTCTYVGAAKLKELSRRTTFIRVTQ 338 V + ++GG+++ YVGA ++EL + F+ +T Sbjct: 424 VSEVLYQLVGGLKAGMGYVGARNIRELKEKGEFVIITH 461 Score = 88.9 bits (219), Expect = 3e-18, Method: Composition-based stats. Identities = 21/120 (17%), Positives = 42/120 (35%), Gaps = 6/120 (5%) Query: 6 NDVKLDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFEMAK 65 F DVLL P+ + ++ + S R + +PI++A MDTV +EMA Sbjct: 11 AIKGYTFDDVLLIPQATEVEPKD-----VDVSTRITPNVKLNIPILSAAMDTVTEWEMAV 65 Query: 66 VLCKFSLFTAVHKHYSLVQWQEFAGQNPDCLEH-LAASSGTGSSDFEQLEQILEAIPQVK 124 + + +H++ + + E + + + L + Sbjct: 66 AMAREGGLGVIHRNMGIEEQVEQVKRVKRAERLIVEDVITIAPDETVDFALFLMEKHGID 125 >4DQW-A nrPDB Length = 509 Score = 293 bits (750), Expect = 7e-80, Method: Composition-based stats. Identities = 93/270 (34%), Positives = 144/270 (53%), Gaps = 12/270 (4%) Query: 78 KHYSLVQWQEFAGQNPDCLEHLAASSGTGSSDFEQLEQILEAIPQVKYICLDVANGYSEH 137 + + A ++ + A+ GTG+ E++ ++ A V + A+G+S+ Sbjct: 218 RDIEKAKTYPLASKDEQGRLRVGAAVGTGADTGERVAALVAAGVDVVVVD--TAHGHSKG 275 Query: 138 FVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYP 197 +E V+ V++ FP ++ GN+ T E + L +GAD +KVGIGPGS+CTTR GVG P Sbjct: 276 VIERVRWVKQTFPDVQVIGGNIATAEAAKALAEAGADAVKVGIGPGSICTTRIVAGVGVP 335 Query: 198 QLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGELIE 257 Q+SA+ A A G +I+DGG GD+AKA AGA VM+G M AG E+ GE+ Sbjct: 336 QISAIANVAAALEGTGVPLIADGGIRFSGDLAKAMVAGAYCVMMGSMFAGTEEAPGEIEL 395 Query: 258 RDGKKYKLFYGMSSEMAMKKYAGGV----------AEYRASEGKTVEVPFKGDVEHTIRD 307 G+ YK + GM S AM G AE EG VP+KG + + Sbjct: 396 FQGRSYKSYRGMGSLGAMSGSQGSSDRYFQDASAGAEKLVPEGIEGRVPYKGALSAIVHQ 455 Query: 308 ILGGIRSTCTYVGAAKLKELSRRTTFIRVT 337 ++GG+R+ Y G+A ++++ + F+R+T Sbjct: 456 LMGGLRAAMGYTGSADIQQMRTQPQFVRIT 485 Score = 97.0 bits (240), Expect = 1e-20, Method: Composition-based stats. Identities = 20/91 (21%), Positives = 36/91 (39%), Gaps = 5/91 (5%) Query: 4 IDNDVKLDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFEM 63 + L F DVLL P S + + S R ++ +P+++A MDTV + Sbjct: 23 RISQEALTFDDVLLIPGYSEVLPKD-----VSLKTRLTRGIELNIPLVSAAMDTVTEARL 77 Query: 64 AKVLCKFSLFTAVHKHYSLVQWQEFAGQNPD 94 A + + +HK+ + Q + Sbjct: 78 AIAMAQEGGIGIIHKNMGIEQQAAEVRKVKK 108 >1AK5-A nrPDB Length = 503 Score = 254 bits (648), Expect = 5e-68, Method: Composition-based stats. Identities = 89/367 (24%), Positives = 153/367 (41%), Gaps = 42/367 (11%) Query: 11 DFKDVLLRPKRSTLKSRSEVD----------------LTRSFSFRNSKQTYSGVP---II 51 F DVL +R+T + + D + +K + P ++ Sbjct: 115 TFADVLAISQRTTHNTVAVTDDGTPHGVLLGLVTQRDYPIDLTQTETKVSDMMTPFSKLV 174 Query: 52 AANMDT-VGTFEMAKVLCKFSLFTAV----HKHY-----SLVQWQEFAGQNPDCLEHLAA 101 A+ DT + K + + H Y + Q + D + Sbjct: 175 TAHQDTKLSEANKIIWEKKLNALPIIDDDQHLRYIVFRKDYDRSQVCHNELVDSQKRYLV 234 Query: 102 SSGTGSSDF-EQLEQILEAIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQHT-IMAGNV 159 +G + DF E++ ++EA +C+D ++G+SE + +R+++ + AGN+ Sbjct: 235 GAGINTRDFRERVPALVEA--GADVLCIDSSDGFSEWQKITIGWIREKYGDKVKVGAGNI 292 Query: 160 VTGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAVMECADAAHGL------K 213 V GE L +GAD IK+GIG GS+C TR++ G+G Q +AV++ + Sbjct: 293 VDGEGFRYLADAGADFIKIGIGGGSICITREQKGIGRGQATAVIDVVAERNKYFEETGIY 352 Query: 214 GHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGELIERDGKKYKLFYGMSSEM 273 + SDGG + A GADF+MLG A ES + +G K ++G S Sbjct: 353 IPVCSDGGIVYDYHMTLALAMGADFIMLGRYFARFEESPTRKVTINGSVMKEYWGEGSSR 412 Query: 274 A--MKKY-AGGVAEYRASEGKTVEVPFKGDVEHTIRDILGGIRSTCTYVGAAKLKELSRR 330 A ++Y GG + EG VP+ G ++ + L ++ST GA + +L + Sbjct: 413 ARNWQRYDLGGKQKLSFEEGVDSYVPYAGKLKDNVEASLNKVKSTMCNCGALTIPQLQSK 472 Query: 331 TTFIRVT 337 V+ Sbjct: 473 AKITLVS 479 Score = 57.0 bits (136), Expect = 1e-08, Method: Composition-based stats. Identities = 19/111 (17%), Positives = 37/111 (33%), Gaps = 4/111 (3%) Query: 11 DFKDVLLRPKRSTLK--SRSEVDLTRSFSFRNSKQ--TYSGVPIIAANMDTVGTFEMAKV 66 F + LL P ST+ + T F+ +Q +P+++A M +V +MA Sbjct: 11 TFNEYLLIPGLSTVDCIPSNVNLSTPLVKFQKGQQSEINLKIPLVSAIMQSVSGEKMAIA 70 Query: 67 LCKFSLFTAVHKHYSLVQWQEFAGQNPDCLEHLAASSGTGSSDFEQLEQIL 117 L + + + S+ + S D + + Sbjct: 71 LAREGGISFIFGSQSIESQAAMVHAVKNFKAGFVVSDSNVKPDQTFADVLA 121 >6BFG-A nrPDB Length = 399 Score = 53.5 bits (127), Expect = 1e-07, Method: Composition-based stats. Identities = 23/108 (21%), Positives = 42/108 (38%), Gaps = 18/108 (16%) Query: 140 EFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQL 199 E ++ +R +P ++ G +++ E + I GAD + + G QL Sbjct: 234 EALRWLRDLWPHKLLVKG-LLSAEDADRCIAEGADGV-------------ILSNHGGRQL 279 Query: 200 SAVME----CADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGG 243 + A + ++ D G D+ KA GA+ V+LG Sbjct: 280 DCAISPMEVLAQSVAKTGKPVLIDSGFRRGSDIVKALALGAEAVLLGR 327 >2A85-A nrPDB Length = 380 Score = 53.5 bits (127), Expect = 1e-07, Method: Composition-based stats. Identities = 23/108 (21%), Positives = 42/108 (38%), Gaps = 18/108 (16%) Query: 140 EFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQL 199 E ++ +R +P ++ G +++ E + I GAD + + G QL Sbjct: 215 EALRWLRDLWPHKLLVKG-LLSAEDADRCIAEGADGV-------------ILSNHGGRQL 260 Query: 200 SAVME----CADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGG 243 + A + ++ D G D+ KA GA+ V+LG Sbjct: 261 DCAISPMEVLAQSVAKTGKPVLIDSGFRRGSDIVKALALGAEAVLLGR 308 >6DVI-A nrPDB Length = 394 Score = 53.1 bits (126), Expect = 2e-07, Method: Composition-based stats. Identities = 28/114 (24%), Positives = 42/114 (36%), Gaps = 10/114 (8%) Query: 133 GYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTTRKKT 192 G+S E + VR + ++ + + + SG D I G R+ Sbjct: 245 GHSV-TWEDIDWVRS-ITKMPVILKGIQHPDDARRAVDSGVDGIYCSNHGG-----RQAN 297 Query: 193 GVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLA 246 G G P L + E A+ ++ D G DV KA GA V +G A Sbjct: 298 G-GLPALDCLPEVVKASGDT--PVLFDSGIRTGADVVKALAMGASAVGIGRPYA 348 >5ZBN-A nrPDB Length = 371 Score = 48.9 bits (115), Expect = 3e-06, Method: Composition-based stats. Identities = 27/120 (22%), Positives = 43/120 (35%), Gaps = 22/120 (18%) Query: 142 VKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQ--- 198 V+ + + I+ V+T E + +GA I + G Q Sbjct: 217 VQWL-QTITSLPILVKGVLTAEDARLAVQAGAAGI-------------IVSNHGARQLDY 262 Query: 199 ----LSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGE 254 + A+ E AA G + + DGG DV KA GA + +G + + GE Sbjct: 263 VPSTIMALEEVVKAAQG-RIPVFLDGGVRRGTDVFKALALGASGIFIGRPVVFSLAAEGE 321 >1AL8-A nrPDB Length = 359 Score = 45.4 bits (106), Expect = 3e-05, Method: Composition-based stats. Identities = 27/115 (23%), Positives = 39/115 (33%), Gaps = 21/115 (18%) Query: 147 KRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQ-------L 199 + I+ V+T E + GA I + G Q + Sbjct: 220 QTITSLPILVKGVITAEDARLAVQHGAAGI-------------IVSNHGARQLDYVPATI 266 Query: 200 SAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGE 254 A+ E AA G + + DGG DV KA GA V +G + + GE Sbjct: 267 MALEEVVKAAQG-RIPVFLDGGVRRGTDVFKALALGAAGVFIGRPVVFSLAAEGE 320 >4N6F-A nrPDB Length = 256 Score = 45.0 bits (105), Expect = 5e-05, Method: Composition-based stats. Identities = 27/146 (18%), Positives = 54/146 (36%), Gaps = 19/146 (13%) Query: 112 QLEQILEAIPQVKYICLDV----ANGYSEHFVEFVKDVRKR-FPQHTIMAGNVVTGEMVE 166 + +IL ++ + LDV + VE +++R + ++ T Sbjct: 95 RSARILRDSLGIEILKLDVRGDDNTPDNAGTVEAARELRAEGMELLPFILPDLAT---AR 151 Query: 167 ELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPG 226 L +G ++V P +G G +A+ E + + ++ +GG Sbjct: 152 ALEEAGCAALRVMASP-------VASGRGIANPAAIRELIE---QIGIPVVVEGGIGSAR 201 Query: 227 DVAKAFGAGADFVMLGGMLAGHSESG 252 VA+A GA ++ L +ES Sbjct: 202 HVAEAMELGASATLVNTALVR-AESP 226 >2CDH-0 nrPDB Length = 226 Score = 43.1 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 27/115 (23%), Positives = 39/115 (33%), Gaps = 21/115 (18%) Query: 147 KRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQ-------L 199 + I+ V+T E + GA I + G Q + Sbjct: 104 QTITSLPILVKGVITAEDARLAVQHGAAGI-------------IVSNHGARQLDYVPATI 150 Query: 200 SAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGE 254 A+ E AA G + + DGG DV KA GA V +G + + GE Sbjct: 151 MALEEVVKAAQG-RIPVFLDGGVRRGTDVFKALALGAAGVFIGRPVVFSLAAEGE 204 >2GJN-A nrPDB Length = 328 Score = 42.7 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 13/46 (28%), Positives = 20/46 (43%) Query: 207 DAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESG 252 AA+ L+ II+ GG + + A GAD + +G E Sbjct: 166 AAANRLRVPIIASGGFADGRGLVAALALGADAINMGTRFLATRECP 211 >1P0K-A nrPDB Length = 349 Score = 41.9 bits (97), Expect = 4e-04, Method: Composition-based stats. Identities = 27/129 (20%), Positives = 48/129 (37%), Gaps = 11/129 (8%) Query: 137 HFVEFVKDV--RKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGS-------VCT 187 ++ ++ + R P G ++ +L +GA + +G G+ + Sbjct: 165 GALKRIEQICSRVSVPVIVKEVGFGMSKASAGKLYEAGAAAVDIGGYGGTNFSKIENLRR 224 Query: 188 TRKKTGVGYPQLSAVMECADAAHGLKGH-IISDGGCSCPGDVAKAFGAGADFV-MLGGML 245 R+ + +S A+ +I+ GG DVAKA GA M G L Sbjct: 225 QRQISFFNSWGISTAASLAEIRSEFPASTMIASGGLQDALDVAKAIALGASCTGMAGHFL 284 Query: 246 AGHSESGGE 254 ++SG E Sbjct: 285 KALTDSGEE 293 >2RDU-A nrPDB Length = 387 Score = 41.2 bits (95), Expect = 6e-04, Method: Composition-based stats. Identities = 30/104 (28%), Positives = 42/104 (40%), Gaps = 8/104 (7%) Query: 140 EFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQL 199 E +K +R R I+A ++ G+ E + G + I V S R+ GV P Sbjct: 237 EDIKWLR-RLTSLPIVAKGILRGDDAREAVKHGLNGILV-----SNHGARQLDGV--PAT 288 Query: 200 SAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGG 243 V+ A K + DGG DV KA GA V +G Sbjct: 289 IDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGR 332 >5GVH-A nrPDB Length = 314 Score = 41.2 bits (95), Expect = 7e-04, Method: Composition-based stats. Identities = 30/218 (13%), Positives = 72/218 (33%), Gaps = 18/218 (8%) Query: 35 SFSFRNSKQTYSGVPIIAANMDTVGTFEMAKVLCKFSLFTAVHKHYSLVQWQEFAGQNPD 94 + R + PI+ M GT +A + + + ++ + + Sbjct: 2 TVRTRVTDLLEIEHPILMGGMAWAGTPTLAAAVSEAGGLGII--GSGAMKPDDLRKAISE 59 Query: 95 CLEHLAASSGTGSSDFEQ-LEQILEAIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQHT 153 + G + +++ + K + G ++ +K+ + Sbjct: 60 LRQKTDKPFGVNIILVSPWADDLVKVCIEEKVPVVTFGAGNPTKYIRELKENGTKVIPV- 118 Query: 154 IMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAVMECADAAHGLK 213 V + + + +GAD + I G ++G +++ + + + Sbjct: 119 -----VASDSLARMVERAGADAV---IAEG------MESGGHIGEVTTFVLVNKVSRSVN 164 Query: 214 GHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSES 251 +I+ GG + +A AF GA+ V +G ES Sbjct: 165 IPVIAAGGIADGRGMAAAFALGAEAVQMGTRFVASVES 202 >3SGZ-A nrPDB Length = 352 Score = 40.4 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 16/45 (35%), Positives = 20/45 (44%), Gaps = 1/45 (2%) Query: 199 LSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGG 243 + A+ E A G K + DGG DV KA GA + LG Sbjct: 259 IDALREVVAAVKG-KIEVYMDGGVRTGTDVLKALALGARCIFLGR 302 >5ZKN-A nrPDB Length = 241 Score = 40.4 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 27/129 (20%), Positives = 50/129 (38%), Gaps = 21/129 (16%) Query: 122 QVKYICLDVA---NGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKV 178 V+ I +D + F+ ++++++P MA ++ + + G DI+ Sbjct: 110 GVQIIAIDATKRERPDRKDLKNFIAEIKEKYPNQLFMA-DISSVDEALYAEKIGFDIVGT 168 Query: 179 GIGPGSVCTTRKKTGVGYPQLS----AVMECADAAHGLKGHIISDGGCSCPGDVAKAFGA 234 T VGY + A+ E +K +I++G P KA Sbjct: 169 -------------TLVGYTDYTKNYKALEELKKVVKVVKIPVIAEGNIDTPLKAKKALEI 215 Query: 235 GADFVMLGG 243 GA V++GG Sbjct: 216 GAFAVVVGG 224 >5LSM-A nrPDB Length = 359 Score = 38.9 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 54/337 (16%), Positives = 94/337 (27%), Gaps = 64/337 (18%) Query: 39 RNSKQTYSGVPIIAANMDTVGTFEMAKVLCKFSLFT----------AVHKHYSLVQWQEF 88 R ++ PII A M V +A + + A+ + ++ Q Sbjct: 4 RLTRLFGIEFPIIQAPMAGVQGSALAIAVSEAGGLGSLPCAMLSLEALEAELTAIRSQTA 63 Query: 89 AGQNPD---CLEHLAASSGTGSSDFEQLEQILEAIPQVKYICLDVANG-YSEHFVEFVKD 144 N + E +A ++ + + E YS+ E + Sbjct: 64 KPINVNFFCHREPVAQAAKQAAWLEQLAPYFAEFNLDPNAQPAGAQRTPYSKAQAEVLAK 123 Query: 145 VRKR-------FPQHTI----------MAGNVVTGEMVEELILSGADII-----KVGIGP 182 + P + + T E L GAD I + G Sbjct: 124 FKPEVVSFHFGLPDEELLLEIKSWGSKVISTATTVEEALWLEARGADAIIAQGLEAGGHR 183 Query: 183 GSVCTTRKKTGVGY----PQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADF 238 G + +G PQ+ A +E +I+ GG V A GA Sbjct: 184 GHFLSEDLTEQLGTFSLLPQIIAAVE---------IPVIAAGGIVDATTVRAAMTMGASA 234 Query: 239 VMLGGMLAGHSESGGELIERDGKKYKLFYGMSSEMAMKKYAGGVAEYRASEGKTVE-VPF 297 V +G E I R+ + S+ A + R + G + Sbjct: 235 VQVGTAYLLCPECNTSAIHREALQ--------SDAAQHTALTNLFSGRPARGIVNRFMAE 286 Query: 298 KGDVEHTIRDI------LGGIRSTCTYVGAAKLKELS 328 G + + D + G+R+ +G L Sbjct: 287 MGPMNEAVPDFPLASSAVAGLRTAAERLGFWDFSPLW 323 >2J6X-A nrPDB Length = 374 Score = 38.5 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 27/110 (24%), Positives = 39/110 (35%), Gaps = 24/110 (21%) Query: 142 VKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVG--------IGPGSVCTTRKKTG 193 ++++ + G + E + I +GA I V PGS T Sbjct: 227 IEEIAAHSGLPVFVKG-IQHPEDADMAIKAGASGIWVSNHGARQLYEAPGSFDT------ 279 Query: 194 VGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGG 243 L A+ E + I+ D G VAKA +GAD V LG Sbjct: 280 -----LPAIAERVNKR----VPIVFDSGVRRGEHVAKALASGADVVALGR 320 >3BW4-A nrPDB Length = 369 Score = 37.3 bits (85), Expect = 0.011, Method: Composition-based stats. Identities = 25/100 (25%), Positives = 40/100 (40%), Gaps = 10/100 (10%) Query: 161 TGEMVEELILSGADII-----KVGIGPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGH 215 T E + +GAD + + G G+ + + G G LS + + +A + Sbjct: 154 TPEEARAVEAAGADAVIAQGVEAGGHQGTHRDSSEDDGAGIGLLSLLAQVREA---VDIP 210 Query: 216 IISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSES--GG 253 +++ GG G +A AGAD LG ES G Sbjct: 211 VVAAGGIMRGGQIAAVLAAGADAAQLGTAFLATDESGAPG 250 >1YXY-A nrPDB Length = 234 Score = 36.6 bits (83), Expect = 0.016, Method: Composition-based stats. Identities = 32/201 (15%), Positives = 68/201 (33%), Gaps = 17/201 (8%) Query: 63 MAKVLCKFSLFTAV------HKHYSLVQWQEFAGQNPDCLEHLAASSGTGSSDFEQLEQI 116 MAK + K + G ++ +QL + Sbjct: 41 MAKAAQEAGAVGIRANSVRDIKEIQAITDLPIIGIIKKDYPPQEPFITATMTEVDQLAAL 100 Query: 117 LEAIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADII 176 A+ + D +G F++ V++++P +MA ++ T + +G D + Sbjct: 101 NIAVIAMDCTKRDRHDG--LDIASFIRQVKEKYPNQLLMA-DISTFDEGLVAHQAGIDFV 157 Query: 177 KVGIGPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGA 236 + G +R++ G + A+ + +I++G P + K G Sbjct: 158 GTTL-SGYTPYSRQEAGPDVALIEALCKA-------GIAVIAEGKIHSPEEAKKINDLGV 209 Query: 237 DFVMLGGMLAGHSESGGELIE 257 +++GG + E IE Sbjct: 210 AGIVVGGAITRPKEIAERFIE 230 >4Q4K-A nrPDB Length = 357 Score = 35.8 bits (81), Expect = 0.026, Method: Composition-based stats. Identities = 21/97 (21%), Positives = 32/97 (32%), Gaps = 12/97 (12%) Query: 161 TGEMVEELILSGADIIKV-GIGPGSVCTTRKKTGVGYPQ-----LSAVMECADAAHGLKG 214 T E + +GAD + GI G GV P+ + + A Sbjct: 158 TPEEAALVEAAGADAVVAQGIEAGG------HRGVFEPERGDAAIGTLALVRLLAARGSL 211 Query: 215 HIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSES 251 +++ GG + A GA V +G ES Sbjct: 212 PVVAAGGIMDGRGIRAALELGASAVQMGTAFVLCPES 248 >4JEJ-A nrPDB Length = 244 Score = 35.8 bits (81), Expect = 0.030, Method: Composition-based stats. Identities = 14/54 (25%), Positives = 24/54 (44%) Query: 192 TGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGML 245 G G + + + + ++ II GG + KA+ AGAD V++G Sbjct: 181 AGSGAKKPVPLEMISVISQNVEIPIIVGGGIVDLHGIKKAYNAGADLVVIGTAF 234 Score = 31.2 bits (69), Expect = 0.73, Method: Composition-based stats. Identities = 15/93 (16%), Positives = 38/93 (40%), Gaps = 3/93 (3%) Query: 90 GQNPDCLEHLAASSGTGSSDFEQLEQILEAI--PQVKYICLDVANGYSEHF-VEFVKDVR 146 N + ++ + +F+ +A K I L+ +G + +E + + Sbjct: 139 SGNETAVARVSKTEPLNRENFDLALATAQAGEMLGSKLIYLEAGSGAKKPVPLEMISVIS 198 Query: 147 KRFPQHTIMAGNVVTGEMVEELILSGADIIKVG 179 + I+ G +V +++ +GAD++ +G Sbjct: 199 QNVEIPIIVGGGIVDLHGIKKAYNAGADLVVIG 231 >1TYG-A nrPDB Length = 253 Score = 35.4 bits (80), Expect = 0.037, Method: Composition-based stats. Identities = 38/201 (18%), Positives = 72/201 (35%), Gaps = 30/201 (14%) Query: 64 AKVLCKFSLFTAVHKHYSLVQ-----WQEFAGQNPDCLEHLAASSGTGSSDFEQLEQILE 118 A + + + T + ++ + + E + L A + T ++ ++ + Sbjct: 29 AVAVSESDILTFAVRRMNIFEASQPNFLEQLDLSKYTLLPNTAGASTAEEAV-RIARLAK 87 Query: 119 AIPQVKYICLDVANGYSEHF----VEFVKDVRKRFPQHTIM----AGNVVTGEMVEELIL 170 A I ++V G S VE +K + + I+ + +VV + +L Sbjct: 88 ASGLCDMIKVEVI-GCSRSLLPDPVETLKASEQLLEEGFIVLPYTSDDVV---LARKLEE 143 Query: 171 SGADIIKVGIGPGSVCTTRKKTGVGYPQ-LSAVMECADAAHGLKGHIISDGGCSCPGDVA 229 G I G P +G Q + + + K +I D G P D A Sbjct: 144 LGVHAIMPGASP-----------IGSGQGILNPLNLSFIIEQAKVPVIVDAGIGSPKDAA 192 Query: 230 KAFGAGADFVMLGGMLAGHSE 250 A GAD V+L ++G + Sbjct: 193 YAMELGADGVLLNTAVSGADD 213 >2Z6J-A nrPDB Length = 332 Score = 35.0 bits (79), Expect = 0.045, Method: Composition-based stats. Identities = 33/229 (14%), Positives = 68/229 (29%), Gaps = 42/229 (18%) Query: 36 FSFRNSKQTYSGVPIIAANMDTVGTFEMAKVLCKFSLFTAVHKHYSLVQWQEFAGQNPDC 95 R ++ PI M V ++A + K Sbjct: 1 MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSK--------------------AGGLGI 40 Query: 96 LEHLAASSGTGSSDFEQLEQILEAIPQVKYI--------CLDVANGYSEHFVEFVKDVRK 147 + A ++ ++++ + + V + +D+ V Sbjct: 41 IGGGNAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPS 100 Query: 148 RFPQHTIMAGNVVTG-----EMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAV 202 ++ + AG +V + + + GAD + I G + G +L+ + Sbjct: 101 KYMERFHEAGIIVIPVVPSVALAKRMEKIGADAV---IAEG------MEAGGHIGKLTTM 151 Query: 203 MECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSES 251 A + +I+ GG + A F GA+ V +G ES Sbjct: 152 TLVRQVATAISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKES 200 >1H1Z-A nrPDB Length = 228 Score = 34.6 bits (78), Expect = 0.062, Method: Composition-based stats. Identities = 23/120 (19%), Positives = 42/120 (35%), Gaps = 8/120 (6%) Query: 67 LCKFSLFTA-VHKHYSLVQWQEFAGQNPDCLEHLAASSGTGSSDFEQLEQILEAIPQVKY 125 L K H S WQE S G+ E++ ++EA V+ Sbjct: 83 LAKAGASGFTFHIEVSRDNWQELIQSIKAKGMRPGVSLRPGT-PVEEVFPLVEAENPVEL 141 Query: 126 ICLDV------ANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVG 179 + + + +E V+ +RK++P I + ++ +GA+ I G Sbjct: 142 VLVMTVEPGFGGQKFMPEMMEKVRALRKKYPSLDIEVDGGLGPSTIDVAASAGANCIVAG 201 >1VHC-A nrPDB Length = 224 Score = 34.2 bits (77), Expect = 0.081, Method: Composition-based stats. Identities = 25/104 (24%), Positives = 37/104 (35%), Gaps = 10/104 (9%) Query: 135 SEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKV-GIGPGSVCTTR---- 189 SE + ++ +R P I AG V+T E V SGAD + G+ P V + Sbjct: 52 SEAAADAIRLLRANRPDFLIAAGTVLTAEQVVLAKSSGADFVVTPGLNPKIVKLCQDLNF 111 Query: 190 -KKTGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAF 232 GV P + + + GG + KA Sbjct: 112 PITPGVNNPMAIEIALEMGISAVKFFPAEASGGVK----MIKAL 151 >3SR7-A nrPDB Length = 365 Score = 33.9 bits (76), Expect = 0.10, Method: Composition-based stats. Identities = 11/27 (40%), Positives = 14/27 (51%) Query: 213 KGHIISDGGCSCPGDVAKAFGAGADFV 239 K I++ GG P D+ KA GA V Sbjct: 278 KVEILASGGIRHPLDIIKALVLGAKAV 304 >1N7K-A nrPDB Length = 234 Score = 33.5 bits (75), Expect = 0.16, Method: Composition-based stats. Identities = 22/69 (31%), Positives = 27/69 (39%), Gaps = 10/69 (14%) Query: 171 SGADIIKVGIGPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAK 230 +GADI+K G T G P V A A L + + GG D Sbjct: 160 AGADIVKTSTG--------VYTKGGDP--VTVFRLASLAKPLGMGVKASGGIRSGIDAVL 209 Query: 231 AFGAGADFV 239 A GAGAD + Sbjct: 210 AVGAGADII 218 >2P8U-A nrPDB Length = 478 Score = 33.1 bits (74), Expect = 0.18, Method: Composition-based stats. Identities = 19/114 (16%), Positives = 37/114 (32%), Gaps = 11/114 (9%) Query: 80 YSLVQW-QEFAGQNPDCLEHLAASSGTGSSDFEQLE----QILEAIPQVKYICLDVAN-- 132 ++VQ E + DC+ L + T + ++ Q+ E +D N Sbjct: 78 MTVVQNLMERNNLSYDCIGRLEVGTETIIDKSKSVKTNLMQLFEESGNTDIEGIDTTNAC 137 Query: 133 -GYSEHFVEFVKDVRKRFPQ---HTIMAGNVVTGEMVEELILSGADIIKVGIGP 182 G + V + ++AG++ G + + IGP Sbjct: 138 YGGTAAVFNAVNWIESSSWDGRYALVVAGDIAVYATGNARPTGGVGAVALLIGP 191 >1MXS-A nrPDB Length = 225 Score = 33.1 bits (74), Expect = 0.19, Method: Composition-based stats. Identities = 14/84 (16%), Positives = 33/84 (39%), Gaps = 11/84 (13%) Query: 113 LEQILEAIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSG 172 + + + + L +G ++ ++ +R++ P+ + AG V+ M + +G Sbjct: 44 ADALAAGGIRTLEVTLRSQHG-----LKAIQVLREQRPELCVGAGTVLDRSMFAAVEAAG 98 Query: 173 ADIIKVGIGPGSVCTTRKKTGVGY 196 A + + PG T G Sbjct: 99 AQFV---VTPG---ITEDILEAGV 116 >2ZRW-A nrPDB Length = 368 Score = 32.7 bits (73), Expect = 0.23, Method: Composition-based stats. Identities = 13/46 (28%), Positives = 18/46 (39%), Gaps = 8/46 (17%) Query: 195 GYPQLSAVMECADAAHGLKGH---IISDGGCSCPGDVAKAFGAGAD 237 G P +++ME ++ GG D AKA GAD Sbjct: 251 GVPTAASIMEV-----RYSVPDSFLVGSGGIRSGLDAAKAIALGAD 291 >1QAP-A nrPDB Length = 296 Score = 32.7 bits (73), Expect = 0.23, Method: Composition-based stats. Identities = 22/72 (30%), Positives = 35/72 (48%), Gaps = 6/72 (8%) Query: 109 DFEQLEQILEAI-PQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEE 167 + E L+++ +A+ I LD N ++ E VK V + ++GNV T E + E Sbjct: 214 EVENLDELDDALKAGADIIMLD--NFNTDQMREAVKRVNGQ--ARLEVSGNV-TAETLRE 268 Query: 168 LILSGADIIKVG 179 +G D I VG Sbjct: 269 FAETGVDFISVG 280 >3F4W-A nrPDB Length = 211 Score = 32.7 bits (73), Expect = 0.26, Method: Composition-based stats. Identities = 16/84 (19%), Positives = 33/84 (39%), Gaps = 18/84 (21%) Query: 139 VEFVKDVRKRFPQHTIMA-GNVVTGEMVEE--LILSGADIIKVGIGPGSVCTTRKKTGVG 195 V +K +++++P ++A ++ G E L +GAD + V +G Sbjct: 41 VNAIKAIKEKYPHKEVLADAKIMDGGHFESQLLFDAGADYVTV---------------LG 85 Query: 196 YPQLSAVMECADAAHGLKGHIISD 219 + + C AA ++ D Sbjct: 86 VTDVLTIQSCIRAAKEAGKQVVVD 109 >1XI3-A nrPDB Length = 215 Score = 32.3 bits (72), Expect = 0.32, Method: Composition-based stats. Identities = 25/136 (18%), Positives = 47/136 (34%), Gaps = 8/136 (5%) Query: 87 EFAGQNPDCLEHLAASSGTGSSDFEQLEQILEAIPQVKYICLDVANGYSEHFVEFVKDVR 146 + +N E E + + +V A+G + +V Sbjct: 44 QMRIKNAPTREMYEIGKTLRQLTRE-YDALFFVDDRVDVALAVDADGVQLGPEDMPIEVA 102 Query: 147 KRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAVMECA 206 K + I+ +V + E E GAD + G GSV T+ K L + + Sbjct: 103 KEIAPNLIIGASVYSLEEALEAEKKGADYL----GAGSVFPTKTKEDARVIGLEGLRKIV 158 Query: 207 DAAHGLKGHIISDGGC 222 ++ +K +++ GG Sbjct: 159 ES---VKIPVVAIGGI 171 >5UE9-A nrPDB Length = 306 Score = 31.9 bits (71), Expect = 0.43, Method: Composition-based stats. Identities = 38/186 (20%), Positives = 70/186 (37%), Gaps = 25/186 (13%) Query: 82 LVQWQEFAGQNPDCLEHLAASSGTGSSDFEQLEQILEAIPQVKYICLDVA-----NGYSE 136 + + + +N L +A +G+ D+ + + P VK I L+++ +G Sbjct: 81 MAEKLPWLNENFPDLPIIANVAGSEEDDYVAVCAKIGDAPNVKVIELNISCPNVKHGGQA 140 Query: 137 HFVE------FVKDVRK--RFPQHTIMAGNVVT-GEMVEELILSGADI---IKVGIGPGS 184 + VK + + P + ++ NV + + + +GAD I +G Sbjct: 141 FGTDPDVAAALVKACKAVSKVPLYVKLSPNVTDIVPIAKAVEAAGADGLTMINTLMGVRF 200 Query: 185 VCTTR------KKTGVGYPQL--SAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGA 236 TR G+ P + A+ A + II GG DV + + AGA Sbjct: 201 DLKTRKPVLANITGGLSGPAIKPVALKLIHQVAQVVDIPIIGMGGVESAQDVLEMYMAGA 260 Query: 237 DFVMLG 242 V +G Sbjct: 261 SAVAVG 266 >5Z9Y-A nrPDB Length = 252 Score = 31.5 bits (70), Expect = 0.48, Method: Composition-based stats. Identities = 13/54 (24%), Positives = 18/54 (33%), Gaps = 3/54 (5%) Query: 190 KKTGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGG 243 TG+G + A ++ D G D A A G D V+L Sbjct: 158 IGTGLGIANPHNIEMIVAGAR---VPVVLDAGIGTASDAALAMELGCDAVLLAS 208 >1EP3-A nrPDB Length = 311 Score = 31.5 bits (70), Expect = 0.51, Method: Composition-based stats. Identities = 22/89 (24%), Positives = 34/89 (38%), Gaps = 11/89 (12%) Query: 165 VEELILSGADI---IKVGIGPGSVCTTR------KKTGVGYPQL--SAVMECADAAHGLK 213 + + +GAD I +G TR G+ P + A+ A + Sbjct: 182 AKAVEAAGADGLTMINTLMGVRFDLKTRQPILANITGGLSGPAIKPVALKLIHQVAQDVD 241 Query: 214 GHIISDGGCSCPGDVAKAFGAGADFVMLG 242 II GG + DV + + AGA V +G Sbjct: 242 IPIIGMGGVANAQDVLEMYMAGASAVAVG 270 Score = 28.5 bits (62), Expect = 4.0, Method: Composition-based stats. Identities = 23/116 (19%), Positives = 46/116 (39%), Gaps = 9/116 (7%) Query: 140 EFVKDVRKRFPQHTIMAGNVVTGEMVEELI-------LSGADIIKVGIGPGSVCTTRKKT 192 E + + + FP+ I+A NV E + + + I++ I +V + Sbjct: 87 EKLPWLNENFPELPIIA-NVAGSEEADYVAVCAKIGDAANVKAIELNISCPNVKHGGQAF 145 Query: 193 GVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAF-GAGADFVMLGGMLAG 247 G +A+++ A + ++ + +AKA AGAD + + L G Sbjct: 146 GTDPEVAAALVKACKAVSKVPLYVKLSPNVTDIVPIAKAVEAAGADGLTMINTLMG 201 >1WV2-A nrPDB Length = 265 Score = 31.5 bits (70), Expect = 0.52, Method: Composition-based stats. Identities = 25/127 (19%), Positives = 44/127 (34%), Gaps = 19/127 (14%) Query: 132 NGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIK------------VG 179 +G++ +E + D + FP V T + E+L+ G D++ Sbjct: 101 DGHNLVKLEVLADQKTLFPNV------VETLKAAEQLVKDGFDVMVYTSDDPIIARQLAE 154 Query: 180 IGPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFV 239 IG +V G G + K ++ D G D A A G + V Sbjct: 155 IGCIAVMPLAGLIGSGLG-ICNPYNLRIILEEAKVPVLVDAGVGTASDAAIAMELGCEAV 213 Query: 240 MLGGMLA 246 ++ +A Sbjct: 214 LMNTAIA 220 >3BIC-A nrPDB Length = 762 Score = 31.5 bits (70), Expect = 0.54, Method: Composition-based stats. Identities = 28/137 (20%), Positives = 44/137 (32%), Gaps = 24/137 (17%) Query: 71 SLFTAVHKHYSLVQWQE---FAGQNPDCLEHLAASSGTGSSD----------FEQLEQIL 117 S VHK + A D + A TG +D F+ ++ Sbjct: 589 SAIKRVHKFMEREGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVA 648 Query: 118 EAIPQVKYICLDV---ANGYSEHFVEFVKDVRKR-FPQHTIMAGNVVTGEMVEELILSGA 173 + + V A G+ E +K++ P +M G V+ + E L G Sbjct: 649 QQAVDADVHAVGVSTLAAGHKTLVPELIKELNSLGRPDILVMCGGVIPPQDYEFLFEVGV 708 Query: 174 DIIKVGIGPGSVCTTRK 190 + GPG TR Sbjct: 709 SNV---FGPG----TRI 718 >6NKE-A nrPDB Length = 252 Score = 31.5 bits (70), Expect = 0.57, Method: Composition-based stats. Identities = 12/53 (22%), Positives = 21/53 (39%) Query: 192 TGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGM 244 G G P+ + + + +I GG P + AGAD ++ G + Sbjct: 173 AGSGAPRPVSEDTISYVKSKINIPLIVGGGIRDPETAMRIALAGADMIVTGSI 225 Score = 31.2 bits (69), Expect = 0.78, Method: Composition-based stats. Identities = 17/88 (19%), Positives = 32/88 (36%), Gaps = 3/88 (3%) Query: 95 CLEHLAASSGTGSSDFEQLEQ--ILEAIPQVKYICLDVANGYSEHFVE-FVKDVRKRFPQ 151 + + ++ S D E + K I + +G E + V+ + Sbjct: 136 TVGRVGKANLIDSFDRETALSYSLAAQYMGFKLIYFEAGSGAPRPVSEDTISYVKSKINI 195 Query: 152 HTIMAGNVVTGEMVEELILSGADIIKVG 179 I+ G + E + L+GAD+I G Sbjct: 196 PLIVGGGIRDPETAMRIALAGADMIVTG 223 >4XBS-A nrPDB Length = 265 Score = 31.5 bits (70), Expect = 0.60, Method: Composition-based stats. Identities = 15/100 (15%), Positives = 35/100 (35%), Gaps = 3/100 (3%) Query: 81 SLVQWQEFAGQNPDCLEHLAASSGTGSSDFEQLEQILEAIPQVKYICLDVANGYSEHFVE 140 + + L+ + ++ + + Q+ E ++ S VE Sbjct: 149 DIQGLADAVHAKGKILKVILENALLTKDEIVRACQLSE-KAGADFVKTSTGFSTSGAKVE 207 Query: 141 FVKDVRKRFPQHTIM--AGNVVTGEMVEELILSGADIIKV 178 VK +R+ + +G + + E +I +GA + V Sbjct: 208 DVKLMRETVGDRLGVKASGGIHSREEALAMIDAGASRMGV 247 >1SZG-A nrPDB Length = 511 Score = 31.2 bits (69), Expect = 0.65, Method: Composition-based stats. Identities = 12/30 (40%), Positives = 13/30 (43%) Query: 216 IISDGGCSCPGDVAKAFGAGADFVMLGGML 245 + DGG DV KA GA V LG Sbjct: 406 VFVDGGVRRGTDVLKALCLGAKGVGLGRPF 435 >3QH2-A nrPDB Length = 221 Score = 31.2 bits (69), Expect = 0.66, Method: Composition-based stats. Identities = 29/126 (23%), Positives = 48/126 (38%), Gaps = 12/126 (9%) Query: 143 KDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAV 202 K +R RFP + +V + E + AD + G V T K G+ + V Sbjct: 102 KQIRARFPHLH-IGRSVHSLEEAVQAEKEDADYVLFG----HVFETDCKKGL---EGRGV 153 Query: 203 MECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFV-MLGGMLAGHSESGGELIERDGK 261 +D + +I+ GG P + AGAD + ++ G+ + E R + Sbjct: 154 SLLSDIKQRISIPVIAIGGM-TPDRLRDVKQAGADGIAVMSGIFSSAE--PLEAARRYSR 210 Query: 262 KYKLFY 267 K K Sbjct: 211 KLKEMR 216 >1QCW-A nrPDB Length = 410 Score = 31.2 bits (69), Expect = 0.70, Method: Composition-based stats. Identities = 12/30 (40%), Positives = 13/30 (43%) Query: 216 IISDGGCSCPGDVAKAFGAGADFVMLGGML 245 + DGG DV KA GA V LG Sbjct: 305 VFVDGGVRRGTDVLKALCLGAKGVGLGRPF 334 >5VIS-A nrPDB Length = 275 Score = 30.8 bits (68), Expect = 0.86, Method: Composition-based stats. Identities = 27/91 (29%), Positives = 41/91 (45%), Gaps = 15/91 (16%) Query: 165 VEELILSGADIIKVG---IGPGSVCTT-RKKTGVGYPQLSAVMECADAAHGLKGHIISDG 220 EL+ GADII++G GPGS T ++ P + A+ A+ I D Sbjct: 36 ARELLSQGADIIEIGGESTGPGSNTITADEELARIVPVIRAIRSSLPDAN-----IAVD- 89 Query: 221 GCSCPGDVA-KAFGAGADFVMLGGMLAGHSE 250 + +VA KA GA M+ + AG ++ Sbjct: 90 --TYKAEVARKALELGAT--MINDVSAGRAD 116 >2A1T-A nrPDB Length = 421 Score = 30.8 bits (68), Expect = 0.94, Method: Composition-based stats. Identities = 16/72 (22%), Positives = 26/72 (36%), Gaps = 5/72 (6%) Query: 201 AVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGELIERDG 260 A E I+ GD+A A ++ G ++E E + RD Sbjct: 340 AAWEVDSGRRNTYYASIAKA---FAGDIANQLATDAVQILGGNGF--NTEYPVEKLMRDA 394 Query: 261 KKYKLFYGMSSE 272 K Y+++ G S Sbjct: 395 KIYQIYEGTSQI 406 >6CTY-A nrPDB Length = 372 Score = 30.8 bits (68), Expect = 0.97, Method: Composition-based stats. Identities = 21/147 (14%), Positives = 52/147 (35%), Gaps = 22/147 (14%) Query: 108 SDFEQLEQILEAIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEE 167 +++ L +V +D+ + + + ++ +R++FP+ I+ ++ T + + Sbjct: 152 EQMQKIGMPLLIHGEVTDAAVDIFDREARFIDQILEPIRQKFPELKIVFEHITTKDAADY 211 Query: 168 LILSGADIIKVGIGPGSVCTTRKKTGVG--YPQLSAVMECADAAHGLKGHIISDGGCSCP 225 +L+G + + P + R VG P L + + H Sbjct: 212 -VLAGNRFLGATVTPQHLMFNRNHMLVGGIRPHLFCLPILKRSTHQQA------------ 258 Query: 226 GDVAKAFGAGADFVMLGGMLAGHSESG 252 + A +G+D G + Sbjct: 259 --LRAAVASGSD-----RFFLGTDSAP 278 >4MM1-A nrPDB Length = 250 Score = 30.8 bits (68), Expect = 0.97, Method: Composition-based stats. Identities = 20/81 (24%), Positives = 29/81 (35%), Gaps = 7/81 (8%) Query: 192 TGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSES 251 G G P+ A +I GG D A+ GAGAD V+ G ++ Sbjct: 175 AGSGAPEHVPEEMIALVKRCTDQILIVGGGIRSGEDAARVAGAGADVVVTGTVVENSDN- 233 Query: 252 GGELIERDGKKYKLFYGMSSE 272 + K ++ GM S Sbjct: 234 ------VEDKIREIVEGMGSV 248 Score = 28.9 bits (63), Expect = 3.2, Method: Composition-based stats. Identities = 15/60 (25%), Positives = 29/60 (48%), Gaps = 1/60 (1%) Query: 121 PQVKYICLDVANGYSEHF-VEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVG 179 ++ L+ +G EH E + V++ Q I+ G + +GE + +GAD++ G Sbjct: 166 LGMRLFYLEAGSGAPEHVPEEMIALVKRCTDQILIVGGGIRSGEDAARVAGAGADVVVTG 225 >1OFP-A nrPDB Length = 370 Score = 30.4 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 19/105 (18%), Positives = 29/105 (27%), Gaps = 5/105 (4%) Query: 77 HKHYSLVQWQEFAGQNPDCLEHLAASS-----GTGSSDFEQLEQILEAIPQVKYICLDVA 131 H + + A EH GT E + + +D + Sbjct: 222 HHFMGVTKHGVAAITTTKGNEHCFVILRGGKKGTNYDAKSVAEAKAQLPAGSNGLMIDYS 281 Query: 132 NGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADII 176 +G S V + N +TG M+E I G I Sbjct: 282 HGNSNKDFRNQPKVNDVVCEQIANGENAITGVMIESNINEGNQGI 326 >4WY0-A nrPDB Length = 305 Score = 30.4 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 14/45 (31%), Positives = 23/45 (51%), Gaps = 2/45 (4%) Query: 139 VEFVKDVRK--RFPQHTIMAGNVVTGEMVEELILSGADIIKVGIG 181 VE ++++++ R P AG V T ++ GAD + VG G Sbjct: 203 VEVLREIKRLGRLPVVNFAAGGVTTPADAALMMHLGADGVFVGSG 247 Score = 28.1 bits (61), Expect = 5.4, Method: Composition-based stats. Identities = 15/49 (30%), Positives = 21/49 (42%), Gaps = 3/49 (6%) Query: 198 QLSAVMECADAAHGLK-GHII--SDGGCSCPGDVAKAFGAGADFVMLGG 243 QL A +E L ++ + GG + P D A GAD V +G Sbjct: 198 QLGAPVEVLREIKRLGRLPVVNFAAGGVTTPADAALMMHLGADGVFVGS 246 >3O07-A nrPDB Length = 291 Score = 30.0 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 11/36 (30%), Positives = 15/36 (41%) Query: 146 RKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIG 181 + + P AG V T L+ G D + VG G Sbjct: 196 KGKLPVVNFAAGGVATPADAALLMQLGCDGVFVGSG 231 >5KSD-A nrPDB Length = 833 Score = 30.0 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 9/36 (25%), Positives = 15/36 (41%) Query: 51 IAANMDTVGTFEMAKVLCKFSLFTAVHKHYSLVQWQ 86 I M TV + MA + S A+ K + ++ Sbjct: 274 IPIAMPTVLSVTMAIGSHRLSQQGAITKRMTAIEEM 309 >2ISS-A nrPDB Length = 313 Score = 30.0 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 15/45 (33%), Positives = 24/45 (53%), Gaps = 2/45 (4%) Query: 139 VEFVKDVRK--RFPQHTIMAGNVVTGEMVEELILSGADIIKVGIG 181 VE +++V++ R P AG V T +++ GAD + VG G Sbjct: 214 VELLREVKRLGRLPVVNFAAGGVATPADAALMMMLGADGVFVGSG 258 >2ZBT-A nrPDB Length = 297 Score = 30.0 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 13/44 (29%), Positives = 17/44 (38%), Gaps = 2/44 (4%) Query: 140 EFVKDVRKR--FPQHTIMAGNVVTGEMVEELILSGADIIKVGIG 181 E VK V P AG + T ++ G D + VG G Sbjct: 197 ELVKWVHDHGRLPVVNFAAGGIATPADAALMMHLGMDGVFVGSG 240 >1EUA-A nrPDB Length = 213 Score = 30.0 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 31/71 (43%), Gaps = 8/71 (11%) Query: 113 LEQILEAIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSG 172 + ++ +V + L E V+ ++ + K P+ + AG V+ + + E+ +G Sbjct: 33 AKALVAGGVRVLEVTLRT-----ECAVDAIRAIAKEVPEAIVGAGTVLNPQQLAEVTEAG 87 Query: 173 ADIIKVGIGPG 183 A I PG Sbjct: 88 AQF---AISPG 95 >5G1T-A nrPDB Length = 256 Score = 30.0 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 18/90 (20%), Positives = 34/90 (37%), Gaps = 3/90 (3%) Query: 105 TGSSDFEQLEQILEAIPQVKYIC-LDVANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGE 163 G+ +L+ V ++ L A ++ + +K + + G V T E Sbjct: 30 YGNDPLPRLQDYAAQGAGVLHLVDLTGAKDPAKRQIPLIKTLVAGVNVPVQVGGGVRTEE 89 Query: 164 MVEELILSGADIIKVGIGPGSVCTTRKKTG 193 V L+ +G +V IG +V + G Sbjct: 90 DVAALLKAGV--ARVVIGSTAVKSPDVVKG 117 Score = 27.7 bits (60), Expect = 8.0, Method: Composition-based stats. Identities = 10/33 (30%), Positives = 14/33 (42%) Query: 211 GLKGHIISDGGCSCPGDVAKAFGAGADFVMLGG 243 G+ + GG DVA AG V++G Sbjct: 74 GVNVPVQVGGGVRTEEDVAALLKAGVARVVIGS 106 >2GGG-A nrPDB Length = 375 Score = 30.0 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 32/216 (14%), Positives = 63/216 (29%), Gaps = 52/216 (24%) Query: 43 QTYSGVPIIAANMDTVGTFEMAKVLCKFSLFTAVHKHYSLVQWQEFAGQNPDCLEHLAAS 102 QT++ ++ + + MA+ + + + + + + E + Sbjct: 85 QTFANPEAVSDALGSYRGNRMARAMVEMAAWDLWARTLGV----PLGTLLGGHKEQVEVG 140 Query: 103 SGTGSSDFEQLEQILEAIPQVKYICLDVANGYSE--------HFVEFVKDVRKRFPQHTI 154 G EQ V + V GY V+ V+ R+ FP + Sbjct: 141 VSLGIQADEQA--------TVDLVRRHVEQGYRRIKLKIKPGWDVQPVRATREAFPDIRL 192 Query: 155 MAGNVVTGEMVEELILSGA-------DIIKVGIGPGSVCTTRKKTGVGYPQLSA---VME 204 V L +G D+ + Q A +++ Sbjct: 193 ----TVDANSAYTLADAGRLRQLDEYDLTYI------------------EQPLAWDDLVD 230 Query: 205 CADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVM 240 A+ A ++ + D + D KA GA V+ Sbjct: 231 HAELARRIRTPLCLDESVASASDARKALALGAGGVI 266 >1KA9-F nrPDB Length = 252 Score = 30.0 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 19/87 (21%), Positives = 31/87 (35%), Gaps = 6/87 (6%) Query: 146 RKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAVMEC 205 R FP+ + G V TG E + G + +G G + T G + + Sbjct: 135 RGDFPEVHVAGGRVPTGLHAVEWAVKGVE-----LGAGEILLTSMDRD-GTKEGYDLRLT 188 Query: 206 ADAAHGLKGHIISDGGCSCPGDVAKAF 232 A + +I+ GG +AF Sbjct: 189 RMVAEAVGVPVIASGGAGRMEHFLEAF 215 Score = 29.6 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 21/111 (18%), Positives = 35/111 (31%), Gaps = 23/111 (20%) Query: 146 RKRFPQHTIMAGNVVTG-------------EMVEELILSGADIIKVGIGPGSVCTTRKKT 192 ++ P + AG VV G E +GAD + + T ++ Sbjct: 5 KRIVPCLDVHAGRVVKGVNFVNLRDAGDPVEAARAYDEAGADELVFL----DISATHEER 60 Query: 193 GVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGG 243 + + A A + + GG D K +GAD V + Sbjct: 61 AI------LLDVVARVAERVFIPLTVGGGVRSLEDARKLLLSGADKVSVNS 105 Score = 28.9 bits (63), Expect = 3.7, Method: Composition-based stats. Identities = 19/73 (26%), Positives = 32/73 (43%), Gaps = 3/73 (4%) Query: 108 SDFEQLEQILEAIPQVKYICLDVANGYSEHFV--EFVKDVRKRFPQHTIMAGNVVTGEMV 165 E EA + + LD++ + E + + V V +R + G V + E Sbjct: 32 DPVEAARAYDEAGAD-ELVFLDISATHEERAILLDVVARVAERVFIPLTVGGGVRSLEDA 90 Query: 166 EELILSGADIIKV 178 +L+LSGAD + V Sbjct: 91 RKLLLSGADKVSV 103 >3OIX-A nrPDB Length = 345 Score = 30.0 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 14/55 (25%), Positives = 18/55 (32%), Gaps = 4/55 (7%) Query: 200 SAVMECADAAHGLK--GHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESG 252 +A+ L II GG D + GA V +G L H E Sbjct: 260 TALANVHAFYKRLNPSIQIIGTGGVKTGRDAFEHILCGASMVQIGTAL--HQEGP 312 >4IQL-A nrPDB Length = 333 Score = 30.0 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 31/216 (14%), Positives = 65/216 (30%), Gaps = 20/216 (9%) Query: 39 RNSKQTYSGVPIIAANMDTVGTFEMAKVLCKFSLFTAVHKHYSLVQWQE--FAGQNPDCL 96 R + PII+ M +++A + + E Sbjct: 23 RICELLGIEHPIISGGMVWCSGWKLASAVSNCGGLGLIGAGSMHPDNLEHHIRSCKAATD 82 Query: 97 EHLAASSGTGSSDFEQLEQILEAIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMA 156 + + + +++ +I+ V + + G + + +K + Sbjct: 83 KPFGVNVPLLYPEMDKIMEII-MREHVPVVV--TSAGSPKVWTAKLKAAGSKVIHV---- 135 Query: 157 GNVVTGEMVEELILSGADIIKV-GIGPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGH 215 V + + +G D I G G G + + + + + Sbjct: 136 --VSSATFARKSEAAGVDAIVAEGFEAGG--------HNGREETTTLCLIPEVVDAVNIP 185 Query: 216 IISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSES 251 +++ GG + VA A GAD V +G A ES Sbjct: 186 VVAAGGIASGRAVAAALALGADAVQVGTRFALSEES 221 >6HYE-A nrPDB Length = 314 Score = 29.6 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 11/49 (22%), Positives = 20/49 (40%), Gaps = 3/49 (6%) Query: 198 QLSAVMECADAAHGLK-GHII--SDGGCSCPGDVAKAFGAGADFVMLGG 243 ++SA + + ++ + GG + P D A G D V +G Sbjct: 209 KISAPYDLVAQTKQMGRVPVVQFASGGITTPADAALMMQLGCDGVFVGS 257 >4FQU-A nrPDB Length = 313 Score = 29.6 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 18/114 (15%), Positives = 30/114 (26%), Gaps = 16/114 (14%) Query: 242 GGMLAGHSESGGELIERDG------------KKYKLFYGMSSEMAMKKYAGGVAEYRASE 289 GG+ AG G G + K M S + Y G Sbjct: 32 GGLDAGFRGEPGRYHLYAGFACPWAHRVLIMRALKGLEEMISVSMVNAYMGENGWTFLPG 91 Query: 290 GKTVEVPFKGDVEHTIRDILGGIRSTCTYVGAAKLKELSRRTTFIRVTQQVNPI 343 VP + + + + TY G + L + + + + I Sbjct: 92 --DDVVPDSINGADYLYQVYTA--ADPTYTGRVTIPILWDKVEKRILNNESSEI 141 >4UTT-A nrPDB Length = 229 Score = 29.6 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 10/31 (32%), Positives = 17/31 (54%) Query: 213 KGHIISDGGCSCPGDVAKAFGAGADFVMLGG 243 K +I +G + P ++ KA GA ++GG Sbjct: 183 KIPVICEGRINTPEELKKALDLGAYSAVVGG 213 >2NV2-A nrPDB Length = 294 Score = 29.2 bits (64), Expect = 2.5, Method: Composition-based stats. Identities = 11/34 (32%), Positives = 15/34 (44%) Query: 148 RFPQHTIMAGNVVTGEMVEELILSGADIIKVGIG 181 + P AG V T ++ GAD + VG G Sbjct: 204 KLPVVNFAAGGVATPADAALMMQLGADGVFVGSG 237 >1Y0E-A nrPDB Length = 223 Score = 29.2 bits (64), Expect = 2.5, Method: Composition-based stats. Identities = 20/84 (23%), Positives = 35/84 (41%), Gaps = 13/84 (15%) Query: 118 EAIPQVKYICLDVANGYSEHF---------VEFVKDVRKRFPQHTIMAGNVVTGEMVEEL 168 A YI +GY+ + +F+KDV + I GNV+T +M + + Sbjct: 135 AARLGFDYIGT-TLHGYTSYTQGQLLYQNDFQFLKDVLQSVDAKVIAEGNVITPDMYKRV 193 Query: 169 ILSGADIIKVGIGPGSVCTTRKKT 192 + G VG G++ ++ T Sbjct: 194 MDLGVHCSVVG---GAITRPKEIT 214 >4X2R-A nrPDB Length = 250 Score = 29.2 bits (64), Expect = 2.6, Method: Composition-based stats. Identities = 15/80 (18%), Positives = 27/80 (33%), Gaps = 11/80 (13%) Query: 163 EMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIISDGGC 222 E + + +GA+ I + G + ++E + + GG Sbjct: 37 EAARDWVEAGAEWIHL---------VDLDAAFGRGSNAPLLE--RIVGEVGIKVELSGGI 85 Query: 223 SCPGDVAKAFGAGADFVMLG 242 + +A AGA V LG Sbjct: 86 RDDASLTRALKAGAARVNLG 105 >6DU6-A nrPDB Length = 565 Score = 29.2 bits (64), Expect = 2.8, Method: Composition-based stats. Identities = 32/174 (18%), Positives = 60/174 (34%), Gaps = 23/174 (13%) Query: 106 GSSDFEQLEQILEAIPQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMV 165 S+ ++ + V I + + ++ ++ + ++ + + + + Sbjct: 236 AVSEKDKSDLQFGVEQGVDVIF--ASFIRNAAALKEIRTILGEKGKNIKIISKIENQQGM 293 Query: 166 EEL--ILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIIS----- 218 + L I++ +D I V G + +K V Q S + C + +I Sbjct: 294 QNLDAIIAASDGIMVARGDLGIEIPAEK--VFLAQKSMIARC----NRAGKPVICATQML 347 Query: 219 DGGCSCP-------GDVAKAFGAGADFVMLGGMLAGHSESGGELIERDGKKYKL 265 + P DVA A GAD VML G A E E + K K Sbjct: 348 ESMIKKPRPTRAEISDVANAIIDGADCVMLSGETA-KGEYPLECVLTMAKTCKE 400 >2HTM-A nrPDB Length = 268 Score = 28.9 bits (63), Expect = 3.2, Method: Composition-based stats. Identities = 19/110 (17%), Positives = 37/110 (33%), Gaps = 11/110 (10%) Query: 143 KDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTTRKKTGVGYPQLSAV 202 + + + F M ++V + + L + + IG G TR A+ Sbjct: 119 RLIEEDFLVLPYMGPDLVLAKRLAALGTATVMPLAAPIGSGWGVRTR-----------AL 167 Query: 203 MECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESG 252 +E ++ D G P A+ G D V++ +A + Sbjct: 168 LELFAREKASLPPVVVDAGLGLPSHAAEVMELGLDAVLVNTAIAEAQDPP 217 >3W0K-A nrPDB Length = 330 Score = 28.9 bits (63), Expect = 3.3, Method: Composition-based stats. Identities = 8/37 (21%), Positives = 16/37 (43%), Gaps = 5/37 (13%) Query: 134 YSEHFVEFVKDVRKRFPQHTIM-----AGNVVTGEMV 165 ++ + V+ +RK P I+ GN+ E+ Sbjct: 151 HASLIIRTVEAIRKIDPDREIVIDGLGGGNIAMPELA 187 >3MDE-A nrPDB Length = 385 Score = 28.9 bits (63), Expect = 3.4, Method: Composition-based stats. Identities = 12/49 (24%), Positives = 20/49 (40%), Gaps = 2/49 (4%) Query: 224 CPGDVAKAFGAGADFVMLGGMLAGHSESGGELIERDGKKYKLFYGMSSE 272 D+A A V G ++E E + RD K Y+++ G + Sbjct: 325 YAADIANQLATDAVQVFGGNGF--NTEYPVEKLMRDAKIYQIYEGTAQI 371 >4HPN-A nrPDB Length = 378 Score = 28.9 bits (63), Expect = 3.6, Method: Composition-based stats. Identities = 9/65 (13%), Positives = 20/65 (30%), Gaps = 1/65 (1%) Query: 87 EFAGQNPDCLEHLAASSGTGSSDFEQLEQILEAIPQVKY-ICLDVANGYSEHFVEFVKDV 145 E A + + G G + ++ + + +D +GY+ + D Sbjct: 151 EMAERRAEGFHACKIKIGFGVEEDLRVIAAVREAIGPDMRLMIDANHGYTVTEAITLGDR 210 Query: 146 RKRFP 150 F Sbjct: 211 AAGFG 215 >4HDR-A nrPDB Length = 348 Score = 28.9 bits (63), Expect = 3.7, Method: Composition-based stats. Identities = 12/74 (16%), Positives = 28/74 (37%) Query: 122 QVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIG 181 + +D+ +V + + + G +T E + + +G DI+ + Sbjct: 109 GADMVVVDMGVAGDLSYVPGLWHRKIAYGTQDFTEGPAMTREQAIQAVETGIDIVNDRVK 168 Query: 182 PGSVCTTRKKTGVG 195 G+ C + G+G Sbjct: 169 HGNRCFCLGEMGIG 182 >3W7D-A nrPDB Length = 313 Score = 28.9 bits (63), Expect = 3.8, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 26/81 (32%), Gaps = 14/81 (17%) Query: 200 SAVMECADAAHGLKGHIISDGGCSCPG-DVAKAFGAGADFVMLGGMLAGHSESGG----- 253 +A+ ++ G G D AGA V +G L E G Sbjct: 229 TALANVNAFYRRCPDKLVFGCGGVYSGEDAFLHILAGASMVQVGTAL--QEEGPGIFTRL 286 Query: 254 -----ELIERDG-KKYKLFYG 268 E++ R G + + F G Sbjct: 287 EDELLEIMARKGYRTLEEFRG 307 >5UMF-A nrPDB Length = 235 Score = 28.9 bits (63), Expect = 3.8, Method: Composition-based stats. Identities = 14/50 (28%), Positives = 24/50 (48%), Gaps = 1/50 (2%) Query: 198 QLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAG 247 Q+ A+++ + G + I DGG ++A AGAD + G + G Sbjct: 167 QVRAMLDRYEGKSGRRIAIEVDGGIKTD-NIAAVARAGADTFVAGSAIFG 215 >1X7D-A nrPDB Length = 350 Score = 28.5 bits (62), Expect = 4.0, Method: Composition-based stats. Identities = 10/58 (17%), Positives = 19/58 (32%) Query: 75 AVHKHYSLVQWQEFAGQNPDCLEHLAASSGTGSSDFEQLEQILEAIPQVKYICLDVAN 132 A HKH + + + + +A + + EA+ V I A+ Sbjct: 147 AFHKHLGIEEIVAYDTDPLATAKLIANLKEYSGLTIRRASSVAEAVKGVDIITTVTAD 204 >1JUE-A nrPDB Length = 311 Score = 28.5 bits (62), Expect = 4.7, Method: Composition-based stats. Identities = 14/55 (25%), Positives = 19/55 (34%), Gaps = 4/55 (7%) Query: 200 SAVMECADAAHGLK--GHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESG 252 +A+ LK II GG D + GA + +G L H E Sbjct: 227 TALANVRAFYTRLKPEIQIIGTGGIETGQDAFEHLLCGATMLQIGTAL--HKEGP 279 >1PS9-A nrPDB Length = 671 Score = 28.5 bits (62), Expect = 4.8, Method: Composition-based stats. Identities = 17/59 (28%), Positives = 24/59 (40%), Gaps = 13/59 (22%) Query: 136 EHFVEFVKDVRKRFPQHTIM------------AGNVV-TGEMVEELILSGADIIKVGIG 181 VE V+ VR+R I+ G T E+ + + +GA II GIG Sbjct: 192 RFAVEVVRAVRERVGNDFIIIYRLSMLDLVEDGGTFAETVELAQAIEAAGATIINTGIG 250 >4EVZ-A nrPDB Length = 258 Score = 28.5 bits (62), Expect = 4.9, Method: Composition-based stats. Identities = 9/42 (21%), Positives = 16/42 (38%) Query: 200 SAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVML 241 + + A + + GG D ++ AGAD V + Sbjct: 61 TMLEVVERTAEQVFIPLTVGGGIRSVEDASRLLRAGADKVSI 102 >1VH7-A nrPDB Length = 265 Score = 28.5 bits (62), Expect = 4.9, Method: Composition-based stats. Identities = 18/80 (22%), Positives = 29/80 (36%), Gaps = 6/80 (7%) Query: 139 VEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSV----CTTRKKTGV 194 +E V+ V ++ + G + E ELIL GAD KV I +V T+ Sbjct: 65 LELVEKVAEQIDIPFTVGGGIHDFETASELILRGAD--KVSINTAAVENPSLITQIAQTF 122 Query: 195 GYPQLSAVMECADAAHGLKG 214 G + ++ Sbjct: 123 GSQAVVVAIDAKRVDGEFMV 142 >6EI9-A nrPDB Length = 340 Score = 28.5 bits (62), Expect = 5.2, Method: Composition-based stats. Identities = 12/77 (15%), Positives = 33/77 (42%), Gaps = 12/77 (15%) Query: 111 EQLEQILEAIPQVKYICLDVANG-------YSEHFVEFVKDVRKRFPQHTIMAGNVVTGE 163 E++ Q+ E ++ + + +G E + ++ V+++ I G++ Sbjct: 171 EEIAQLAE-DCGIQALTI---HGRTRACLFNGEAEYDSIRAVKQKVSIPVIANGDITDPL 226 Query: 164 MVEELIL-SGADIIKVG 179 ++ +GAD + +G Sbjct: 227 KARAVLDYTGADALMIG 243 >4L4U-A nrPDB Length = 447 Score = 28.1 bits (61), Expect = 5.5, Method: Composition-based stats. Identities = 18/104 (17%), Positives = 41/104 (39%), Gaps = 10/104 (9%) Query: 77 HKH-YSLVQWQEFAGQNPDCLEHLAASSGTGSSDFEQLEQILEAIPQVKYICLDVANGYS 135 H + + + F G + L + E + + E V + L + + Sbjct: 8 HMNVLVIEDDKVFRGLLEEYLSMKGIKVESAERGKEAYKLLSEKHFNVVLLDLLLPDVNG 67 Query: 136 EHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVG 179 +E +K +++R P+ ++ V+TG I + + +K+G Sbjct: 68 ---LEILKWIKERSPETEVI---VITGHGT---IKTAVEAMKMG 102 >1NY5-A nrPDB Length = 387 Score = 28.1 bits (61), Expect = 5.5, Method: Composition-based stats. Identities = 17/98 (17%), Positives = 39/98 (39%), Gaps = 9/98 (9%) Query: 82 LVQWQEFAGQNPDCLEHLAASSGTGSSDFEQLEQILEAIPQVKYICLDVANGYSEHFVEF 141 + + F G + L + E + + E V + L + + +E Sbjct: 6 IEDDKVFRGLLEEYLSMKGIKVESAERGKEAYKLLSEKHFNVVLLDLLLPDVNG---LEI 62 Query: 142 VKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVG 179 +K +++R P+ ++ V+TG I + + +K+G Sbjct: 63 LKWIKERSPETEVI---VITGHGT---IKTAVEAMKMG 94 >3NL2-A nrPDB Length = 540 Score = 28.1 bits (61), Expect = 5.6, Method: Composition-based stats. Identities = 13/61 (21%), Positives = 26/61 (42%), Gaps = 2/61 (3%) Query: 123 VKYICLDVANGYSEHFVEF-VKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIK-VGI 180 + A+G + + +RK ++ +V E V+EL G D++ +G+ Sbjct: 78 IDVAMAIGADGIHVGQDDMPIPMIRKLVGPDMVIGWSVGFPEEVDELSKMGPDMVDYIGV 137 Query: 181 G 181 G Sbjct: 138 G 138 >4AXK-A nrPDB Length = 250 Score = 28.1 bits (61), Expect = 5.7, Method: Composition-based stats. Identities = 14/57 (24%), Positives = 22/57 (38%) Query: 206 ADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGELIERDGKK 262 A+ L + GG + +A GA V +G E ++I R G+K Sbjct: 67 AEITRQLDIKVELTGGIRDDASLERALATGATRVNIGTAALEKPEWIADVIRRHGEK 123 >5EY5-A nrPDB Length = 273 Score = 28.1 bits (61), Expect = 5.9, Method: Composition-based stats. Identities = 11/20 (55%), Positives = 16/20 (80%) Query: 161 TGEMVEELILSGADIIKVGI 180 T E+V L+ +GADII++GI Sbjct: 33 TLELVRALVEAGADIIELGI 52 >5D2Y-A nrPDB Length = 264 Score = 28.1 bits (61), Expect = 6.0, Method: Composition-based stats. Identities = 29/114 (25%), Positives = 41/114 (35%), Gaps = 11/114 (9%) Query: 139 VEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSV----CTTRKKTGV 194 +E V+ V ++ + G + E ELIL GAD KV I +V T+ Sbjct: 64 LELVEKVAEQIDIPFTVGGGIHDFETASELILRGAD--KVEINTAAVENPSLITQIAQTF 121 Query: 195 GYPQLSAVMECADAAHGLKGHIISDG----GCSCPGDVAKAFGAGADFVMLGGM 244 G Q V A G G G V + GA ++LG + Sbjct: 122 GS-QAVVVYIAAKRVDGEFMVFTYSGKKNTGILLRDWVVEVEKRGAGEIVLGSI 174 >1ZY2-A nrPDB Length = 150 Score = 28.1 bits (61), Expect = 6.2, Method: Composition-based stats. Identities = 17/98 (17%), Positives = 39/98 (39%), Gaps = 9/98 (9%) Query: 82 LVQWQEFAGQNPDCLEHLAASSGTGSSDFEQLEQILEAIPQVKYICLDVANGYSEHFVEF 141 + + F G + L + E + + E V + L + + +E Sbjct: 6 IEDDKVFRGLLEEYLSMKGIKVESAERGKEAYKLLSEKHFNVVLLDLLLPDVNG---LEI 62 Query: 142 VKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVG 179 +K +++R P+ ++ V+TG I + + +K+G Sbjct: 63 LKWIKERSPETEVI---VITGHGT---IKTAVEAMKMG 94 >3OA3-A nrPDB Length = 288 Score = 28.1 bits (61), Expect = 6.5, Method: Composition-based stats. Identities = 24/95 (25%), Positives = 37/95 (38%), Gaps = 23/95 (24%) Query: 147 KRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIG---PG-SVCTTRKKTGVGYPQLSAV 202 + I+AG V++ L+GAD +K G PG S+ +SAV Sbjct: 183 SQLTADEIIAGCVLSS-------LAGADYVKTSTGFNGPGASI--------ENVSLMSAV 227 Query: 203 MECADAAHGLKGHIISDGGCSCPGDVAKAFGAGAD 237 + + +K + GG D K AGA+ Sbjct: 228 CDSLQSETRVK----ASGGIRTIEDCVKMVRAGAE 258 >5CSS-A nrPDB Length = 226 Score = 27.7 bits (60), Expect = 7.2, Method: Composition-based stats. Identities = 7/42 (16%), Positives = 16/42 (38%) Query: 202 VMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGG 243 + + G ++ G DV ++ G GA +++ Sbjct: 158 IEDIVKIYEGTGTSVLVGAGIKTGEDVRRSIGLGARGILVAS 199 >2W6R-A nrPDB Length = 266 Score = 27.7 bits (60), Expect = 8.0, Method: Composition-based stats. Identities = 13/53 (24%), Positives = 20/53 (37%), Gaps = 8/53 (15%) Query: 214 GHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSESGGELIERDGKKYKLF 266 II+ GG +AF AGAD + + E D ++ K + Sbjct: 75 LPIIASGGAGKMEHFLEAFLAGADKALAASVF--------HFREIDMRELKEY 119 >2VEP-A nrPDB Length = 244 Score = 27.7 bits (60), Expect = 8.1, Method: Composition-based stats. Identities = 16/71 (22%), Positives = 24/71 (33%), Gaps = 2/71 (2%) Query: 192 TGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHSES 251 G A++ A+ A + + GG +A A G V LG E Sbjct: 56 AAFGTGDNRALI--AEVAQAMDIKVELSGGIRDDDTLAAALATGCTRVNLGTAALETPEW 113 Query: 252 GGELIERDGKK 262 ++I G K Sbjct: 114 VAKVIAEHGDK 124 >4FMK-A nrPDB Length = 225 Score = 27.7 bits (60), Expect = 8.6, Method: Composition-based stats. Identities = 13/53 (24%), Positives = 22/53 (41%), Gaps = 2/53 (3%) Query: 170 LSGADIIKVGIGPGSVCTTRKKTGVGYP--QLSAVMECADAAHGLKGHIISDG 220 + A+ +V IGP SV R + G P +++ + A + I G Sbjct: 123 ENHAEAQEVTIGPQSVAVARCVSTGGRPPARITWISSLGGEAKDTQEPGIQAG 175 >4B2O-A nrPDB Length = 286 Score = 27.3 bits (59), Expect = 9.1, Method: Composition-based stats. Identities = 17/49 (34%), Positives = 26/49 (53%), Gaps = 7/49 (14%) Query: 138 FVEFVKDVRKRF-PQHTIMAG-NVVTGEMVEE-----LILSGADIIKVG 179 E+V ++ ++ P TI+ G N G+ + E LI SGAD I +G Sbjct: 18 VKEYVPKLKTKYKPHFTIINGENAAHGKGLTEKIYHSLIQSGADAITMG 66 >1IYX-A nrPDB Length = 432 Score = 27.3 bits (59), Expect = 9.3, Method: Composition-based stats. Identities = 15/90 (16%), Positives = 29/90 (32%), Gaps = 2/90 (2%) Query: 30 VDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFEMAKVLCKFSLFTAV--HKHYSLVQWQE 87 V T+ S K + + I + T+ A + K + +TAV H+ Sbjct: 319 VTNTQKLSEGIEKGIANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTI 378 Query: 88 FAGQNPDCLEHLAASSGTGSSDFEQLEQIL 117 + S + + + Q+L Sbjct: 379 SDIAVATNAGQIKTGSLSRTDRIAKYNQLL 408 >5LNS-A nrPDB Length = 316 Score = 27.3 bits (59), Expect = 9.6, Method: Composition-based stats. Identities = 11/34 (32%), Positives = 14/34 (41%) Query: 148 RFPQHTIMAGNVVTGEMVEELILSGADIIKVGIG 181 R P AG V T ++ G D + VG G Sbjct: 220 RLPVVQFAAGGVATPADAALMMQLGCDGVFVGSG 253 >4ADT-A nrPDB Length = 297 Score = 27.3 bits (59), Expect = 9.8, Method: Composition-based stats. Identities = 23/87 (26%), Positives = 38/87 (43%), Gaps = 9/87 (10%) Query: 103 SGTGSSDFEQLEQILEAIPQVKYIC-LDVANGYS-----EHFVEFVKDVRK--RFPQHTI 154 +GTG + E ++ I ++KY+C LD + Y+ ++ + RK R P Sbjct: 155 AGTG-NIIEAIKHIRTVNNEIKYLCSLDESEVYNFAKKLRAPIDLILLTRKLKRLPVVNF 213 Query: 155 MAGNVVTGEMVEELILSGADIIKVGIG 181 AG + T + G D + VG G Sbjct: 214 AAGGIATPADAAMCMQLGMDGVFVGSG 240 >3TI8-A nrPDB Length = 395 Score = 27.3 bits (59), Expect = 9.9, Method: Composition-based stats. Identities = 24/112 (21%), Positives = 41/112 (36%), Gaps = 9/112 (8%) Query: 123 VKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGP 182 V+ +C D NG + + F +D+ AG V++ +G+ VG Sbjct: 207 VECVCRDNWNGMNRPILIFDEDLDYEVGYLC--AGIPTDTPRVQDSSFTGSCTNAVG--- 261 Query: 183 GSVCTTRKKTGVGYPQLSAVME----CADAAHGLKGHIISDGGCSCPGDVAK 230 GS G G+ Q ++V + G + +I DG + K Sbjct: 262 GSGTNNYGVKGFGFRQGNSVWAGRTVSISSRSGFEILLIEDGWIRTSKTIVK 313 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.313 0.136 0.371 Lambda K H 0.267 0.0417 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,588,768 Number of Sequences: 36641 Number of extensions: 564231 Number of successful extensions: 2312 Number of sequences better than 10.0: 146 Number of HSP's better than 10.0 without gapping: 118 Number of HSP's successfully gapped in prelim test: 63 Number of HSP's that attempted gapping in prelim test: 1969 Number of HSP's gapped (non-prelim): 265 length of query: 348 length of database: 10,336,785 effective HSP length: 98 effective length of query: 250 effective length of database: 6,745,967 effective search space: 1686491750 effective search space used: 1686491750 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 60 (27.7 bits)