BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9NZ08 (941 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3QNF-A nrPDB 1962 0.0 3SE6-A nrPDB 987 0.0 3RJO-A nrPDB 860 0.0 5C97-A nrPDB 826 0.0 4KXA-A nrPDB 509 e-144 5LG6-A nrPDB 492 e-139 5LHD-A nrPDB 491 e-139 4WZ9-A nrPDB 380 e-105 1Z1W-A nrPDB 295 7e-80 5DLL-A nrPDB 118 1e-26 5Y1X-A nrPDB 104 2e-22 4QHP-A nrPDB 92 9e-19 4GAA-A nrPDB 89 1e-17 5FWQ-A nrPDB 87 4e-17 4Q4I-A nrPDB 86 1e-16 2XPY-A nrPDB 85 1e-16 3CIA-A nrPDB 81 2e-15 5ZI5-A nrPDB 72 1e-12 4OON-A nrPDB 32 1.2 6C57-A nrPDB 30 3.9 5GUJ-A nrPDB 30 4.1 4NT4-A nrPDB 30 4.2 1AKO-A nrPDB 30 6.3 3CH8-A nrPDB 30 7.3 >3QNF-A nrPDB Length = 954 Score = 1962 bits (5084), Expect = 0.0, Method: Compositional matrix adjust. Identities = 941/941 (100%), Positives = 941/941 (100%) Query: 1 MVFLPLKWSLATMSFLLSSLLALLTVSTPSWCQSTEASPKRSDGTPFPWNKIRLPEYVIP 60 MVFLPLKWSLATMSFLLSSLLALLTVSTPSWCQSTEASPKRSDGTPFPWNKIRLPEYVIP Sbjct: 7 MVFLPLKWSLATMSFLLSSLLALLTVSTPSWCQSTEASPKRSDGTPFPWNKIRLPEYVIP 66 Query: 61 VHYDLLIHANLTTLTFWGTTKVEITASQPTSTIILHSHHLQISRATLRKGAGERLSEEPL 120 VHYDLLIHANLTTLTFWGTTKVEITASQPTSTIILHSHHLQISRATLRKGAGERLSEEPL Sbjct: 67 VHYDLLIHANLTTLTFWGTTKVEITASQPTSTIILHSHHLQISRATLRKGAGERLSEEPL 126 Query: 121 QVLEHPRQEQIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRILAST 180 QVLEHPRQEQIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRILAST Sbjct: 127 QVLEHPRQEQIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRILAST 186 Query: 181 QFEPTAARMAFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGLIEDHFDVTV 240 QFEPTAARMAFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGLIEDHFDVTV Sbjct: 187 QFEPTAARMAFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGLIEDHFDVTV 246 Query: 241 KMSTYLVAFIISDFESVSKITKSGVKVSVYAVPDKINQADYALDAAVTLLEFYEDYFSIP 300 KMSTYLVAFIISDFESVSKITKSGVKVSVYAVPDKINQADYALDAAVTLLEFYEDYFSIP Sbjct: 247 KMSTYLVAFIISDFESVSKITKSGVKVSVYAVPDKINQADYALDAAVTLLEFYEDYFSIP 306 Query: 301 YPLPKQDLAAIPDFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVAHELAHQWF 360 YPLPKQDLAAIPDFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVAHELAHQWF Sbjct: 307 YPLPKQDLAAIPDFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVAHELAHQWF 366 Query: 361 GNLVTMEWWNDLWLNEGFAKFMEFVSVSVTHPELKVGDYFFGKCFDAMEVDALNSSHPVS 420 GNLVTMEWWNDLWLNEGFAKFMEFVSVSVTHPELKVGDYFFGKCFDAMEVDALNSSHPVS Sbjct: 367 GNLVTMEWWNDLWLNEGFAKFMEFVSVSVTHPELKVGDYFFGKCFDAMEVDALNSSHPVS 426 Query: 421 TPVENPAQIREMFDDVSYDKGACILNMLREYLSADAFKSGIVQYLQKHSYKNTKNEDLWD 480 TPVENPAQIREMFDDVSYDKGACILNMLREYLSADAFKSGIVQYLQKHSYKNTKNEDLWD Sbjct: 427 TPVENPAQIREMFDDVSYDKGACILNMLREYLSADAFKSGIVQYLQKHSYKNTKNEDLWD 486 Query: 481 SMASICPTDGVKGMDGFCSRSQHSSSSSHWHQEGVDVKTMMNTWTLQKGFPLITITVRGR 540 SMASICPTDGVKGMDGFCSRSQHSSSSSHWHQEGVDVKTMMNTWTLQKGFPLITITVRGR Sbjct: 487 SMASICPTDGVKGMDGFCSRSQHSSSSSHWHQEGVDVKTMMNTWTLQKGFPLITITVRGR 546 Query: 541 NVHMKQEHYMKGSDGAPDTGYLWHVPLTFITSKSDMVHRFLLKTKTDVLILPEEVEWIKF 600 NVHMKQEHYMKGSDGAPDTGYLWHVPLTFITSKSDMVHRFLLKTKTDVLILPEEVEWIKF Sbjct: 547 NVHMKQEHYMKGSDGAPDTGYLWHVPLTFITSKSDMVHRFLLKTKTDVLILPEEVEWIKF 606 Query: 601 NVGMNGYYIVHYEDDGWDSLTGLLKGTHTAVSSNDRASLINNAFQLVSIGKLSIEKALDL 660 NVGMNGYYIVHYEDDGWDSLTGLLKGTHTAVSSNDRASLINNAFQLVSIGKLSIEKALDL Sbjct: 607 NVGMNGYYIVHYEDDGWDSLTGLLKGTHTAVSSNDRASLINNAFQLVSIGKLSIEKALDL 666 Query: 661 SLYLKHETEIMPVFQGLNELIPMYKLMEKRDMNEVETQFKAFLIRLLRDLIDKQTWTDEG 720 SLYLKHETEIMPVFQGLNELIPMYKLMEKRDMNEVETQFKAFLIRLLRDLIDKQTWTDEG Sbjct: 667 SLYLKHETEIMPVFQGLNELIPMYKLMEKRDMNEVETQFKAFLIRLLRDLIDKQTWTDEG 726 Query: 721 SVSERMLRSQLLLLACVHNYQPCVQRAEGYFRKWKESNGNLSLPVDVTLAVFAVGAQSTE 780 SVSERMLRSQLLLLACVHNYQPCVQRAEGYFRKWKESNGNLSLPVDVTLAVFAVGAQSTE Sbjct: 727 SVSERMLRSQLLLLACVHNYQPCVQRAEGYFRKWKESNGNLSLPVDVTLAVFAVGAQSTE 786 Query: 781 GWDFLYSKYQFSLSSTEKSQIEFALCRTQNKEKLQWLLDESFKGDKIKTQEFPQILTLIG 840 GWDFLYSKYQFSLSSTEKSQIEFALCRTQNKEKLQWLLDESFKGDKIKTQEFPQILTLIG Sbjct: 787 GWDFLYSKYQFSLSSTEKSQIEFALCRTQNKEKLQWLLDESFKGDKIKTQEFPQILTLIG 846 Query: 841 RNPVGYPLAWQFLRKNWNKLVQKFELGSSSIAHMVMGTTNQFSTRTRLEEVKGFFSSLKE 900 RNPVGYPLAWQFLRKNWNKLVQKFELGSSSIAHMVMGTTNQFSTRTRLEEVKGFFSSLKE Sbjct: 847 RNPVGYPLAWQFLRKNWNKLVQKFELGSSSIAHMVMGTTNQFSTRTRLEEVKGFFSSLKE 906 Query: 901 NGSQLRCVQQTIETIEENIGWMDKNFDKIRVWLQSEKLERM 941 NGSQLRCVQQTIETIEENIGWMDKNFDKIRVWLQSEKLERM Sbjct: 907 NGSQLRCVQQTIETIEENIGWMDKNFDKIRVWLQSEKLERM 947 >3SE6-A nrPDB Length = 967 Score = 987 bits (2551), Expect = 0.0, Method: Compositional matrix adjust. Identities = 480/936 (51%), Positives = 651/936 (69%), Gaps = 19/936 (2%) Query: 15 FLLSSLLALLTV----STPSWCQSTE---ASPKRSDGTPFPWNKIRLPEYVIPVHYDLLI 67 + L+++L + + S PS TE A P ++G FPW ++RLP VIP+HYDL + Sbjct: 23 YCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFV 82 Query: 68 HANLTTLTFWGTTKVEITASQPTSTIILHSHHLQISRATLRKGAGERLSE--EPLQVLEH 125 H NLT+L F + K+E+ S T IILHS L+I+ ATL+ R + + L+VL + Sbjct: 83 HPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSY 142 Query: 126 PRQEQIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRILASTQFEPT 185 P EQIALL PE L L Y V + + L + F GFYKSTYRT GE RILA T FEPT Sbjct: 143 PAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPT 202 Query: 186 AARMAFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGLIEDHFDVTVKMSTY 245 ARMAFPCFDEP FKA+FSIKIRRE RH+A+SNMP VK++ + GL+EDHF+ TVKMSTY Sbjct: 203 QARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTY 262 Query: 246 LVAFIISDFESVSKITKSGVKVSVYAVPDKINQADYALDAAVTLLEFYEDYFSIPYPLPK 305 LVA+I+ DF S+S T SGVKVS+YA PDK NQ YAL A++ LL+FYE YF I YPL K Sbjct: 263 LVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSK 322 Query: 306 QDLAAIPDFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVAHELAHQWFGNLVT 365 DL AIPDF GAMENWGL TYRE++LLFD + SSAS KL +T +AHELAHQWFGNLVT Sbjct: 323 LDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVT 382 Query: 366 MEWWNDLWLNEGFAKFMEFVSVSVTHPELKVGDYFFGKCFDAMEVDALNSSHPVSTPVEN 425 MEWWND+WLNEGFAK+ME ++V+ T+PEL+ DYF CF+ + D+LNSS P+S P E Sbjct: 383 MEWWNDIWLNEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAET 442 Query: 426 PAQIREMFDDVSYDKGACILNMLREYLSADAFKSGIVQYLQKHSYKNTKNEDLWDSMASI 485 P QI+EMFD+VSY+KGACILNML+++L + F+ GI+QYL+K SY+N KN+DLW S+++ Sbjct: 443 PTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNS 502 Query: 486 C-PTDGVKGMDGFC-SRSQHSSSSSHWHQEGVDVKTMMNTWTLQKGFPLITITVRGRNVH 543 C +D G G C S + +S+ + E +VK MM TWTLQKG PL+ + G ++ Sbjct: 503 CLESDFTSG--GVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLR 560 Query: 544 MKQEHYMKG---SD---GAPDTGYLWHVPLTFITSKSDMVHRFLLKTKTDVLILPEEVEW 597 ++QE +++G D A YLWH+PLT+ TS S+++HR +LK+KTD L LPE+ W Sbjct: 561 LQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSW 620 Query: 598 IKFNVGMNGYYIVHYEDDGWDSLTGLLKGTHTAVSSNDRASLINNAFQLVSIGKLSIEKA 657 +KFNV NGYYIVHYE GWD L L HT + DR LI++ FQLV G+L+++KA Sbjct: 621 VKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKA 680 Query: 658 LDLSLYLKHETEIMPVFQGLNELIPMYKLMEKRDMNEVETQFKAFLIRLLRDLIDKQTWT 717 LD++ YL+HET + +GL+ L Y +M++R+++++ K +L++ + +ID+Q+W+ Sbjct: 681 LDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWS 740 Query: 718 DEGSVSERMLRSQLLLLACVHNYQPCVQRAEGYFRKWKESNGNLSLPVDVTLAVFAVGAQ 777 D+GSV +RMLRS LL LAC N+ PC+Q+A F +W ES+G L++P DV V++VGAQ Sbjct: 741 DKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQ 800 Query: 778 STEGWDFLYSKYQFSLSSTEKSQIEFALCRTQNKEKLQWLLDESFKGDKIKTQEFPQILT 837 +T GW++L +Y+ S+SS E+++I +AL ++++EKL L++ +G IKTQ +L Sbjct: 801 TTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLH 860 Query: 838 LIGRNPVGYPLAWQFLRKNWNKLVQKFELGSSSIAHMVMGTTNQFSTRTRLEEVKGFFSS 897 I R P G LAW F+R+NW L++KF+LGS I ++ GTT FS++ +L+EVK FF S Sbjct: 861 AIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFES 920 Query: 898 LKENGSQLRCVQQTIETIEENIGWMDKNFDKIRVWL 933 L+ GS L Q +ETI +NI W++KN +R WL Sbjct: 921 LEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWL 956 >3RJO-A nrPDB Length = 419 Score = 860 bits (2222), Expect = 0.0, Method: Compositional matrix adjust. Identities = 413/413 (100%), Positives = 413/413 (100%) Query: 529 GFPLITITVRGRNVHMKQEHYMKGSDGAPDTGYLWHVPLTFITSKSDMVHRFLLKTKTDV 588 GFPLITITVRGRNVHMKQEHYMKGSDGAPDTGYLWHVPLTFITSKSDMVHRFLLKTKTDV Sbjct: 1 GFPLITITVRGRNVHMKQEHYMKGSDGAPDTGYLWHVPLTFITSKSDMVHRFLLKTKTDV 60 Query: 589 LILPEEVEWIKFNVGMNGYYIVHYEDDGWDSLTGLLKGTHTAVSSNDRASLINNAFQLVS 648 LILPEEVEWIKFNVGMNGYYIVHYEDDGWDSLTGLLKGTHTAVSSNDRASLINNAFQLVS Sbjct: 61 LILPEEVEWIKFNVGMNGYYIVHYEDDGWDSLTGLLKGTHTAVSSNDRASLINNAFQLVS 120 Query: 649 IGKLSIEKALDLSLYLKHETEIMPVFQGLNELIPMYKLMEKRDMNEVETQFKAFLIRLLR 708 IGKLSIEKALDLSLYLKHETEIMPVFQGLNELIPMYKLMEKRDMNEVETQFKAFLIRLLR Sbjct: 121 IGKLSIEKALDLSLYLKHETEIMPVFQGLNELIPMYKLMEKRDMNEVETQFKAFLIRLLR 180 Query: 709 DLIDKQTWTDEGSVSERMLRSQLLLLACVHNYQPCVQRAEGYFRKWKESNGNLSLPVDVT 768 DLIDKQTWTDEGSVSERMLRSQLLLLACVHNYQPCVQRAEGYFRKWKESNGNLSLPVDVT Sbjct: 181 DLIDKQTWTDEGSVSERMLRSQLLLLACVHNYQPCVQRAEGYFRKWKESNGNLSLPVDVT 240 Query: 769 LAVFAVGAQSTEGWDFLYSKYQFSLSSTEKSQIEFALCRTQNKEKLQWLLDESFKGDKIK 828 LAVFAVGAQSTEGWDFLYSKYQFSLSSTEKSQIEFALCRTQNKEKLQWLLDESFKGDKIK Sbjct: 241 LAVFAVGAQSTEGWDFLYSKYQFSLSSTEKSQIEFALCRTQNKEKLQWLLDESFKGDKIK 300 Query: 829 TQEFPQILTLIGRNPVGYPLAWQFLRKNWNKLVQKFELGSSSIAHMVMGTTNQFSTRTRL 888 TQEFPQILTLIGRNPVGYPLAWQFLRKNWNKLVQKFELGSSSIAHMVMGTTNQFSTRTRL Sbjct: 301 TQEFPQILTLIGRNPVGYPLAWQFLRKNWNKLVQKFELGSSSIAHMVMGTTNQFSTRTRL 360 Query: 889 EEVKGFFSSLKENGSQLRCVQQTIETIEENIGWMDKNFDKIRVWLQSEKLERM 941 EEVKGFFSSLKENGSQLRCVQQTIETIEENIGWMDKNFDKIRVWLQSEKLERM Sbjct: 361 EEVKGFFSSLKENGSQLRCVQQTIETIEENIGWMDKNFDKIRVWLQSEKLERM 413 >5C97-A nrPDB Length = 912 Score = 826 bits (2133), Expect = 0.0, Method: Compositional matrix adjust. Identities = 419/908 (46%), Positives = 578/908 (63%), Gaps = 38/908 (4%) Query: 37 ASPKRSDGTPFPWNKIRLPEYVIPVHYDLLIHANLTTLTFWGTTKVEITASQPTSTIILH 96 A ++G FPW +IRLP V+P+ Y+L +H NLT++TF G+ + + A Q T IILH Sbjct: 28 AETGATNGKLFPWAQIRLPTAVVPLRYELSLHPNLTSMTFRGSVTISVQALQVTWNIILH 87 Query: 97 SHHLQISRATLRKGAGERLSEEPLQVLEHPRQEQIALLAPEPLLVGLPYTVVIHYAGNLS 156 S ISR T + E+ ++LE+ QIA++APE LL G YT+ I Y+ N+S Sbjct: 88 STGHNISRVTFMSAVSSQ--EKQAEILEYAYHGQIAIVAPEALLAGHNYTLKIEYSANIS 145 Query: 157 ETFHGFYKSTYRTKEGELRILASTQFEPTAARMAFPCFDEPAFKASFSIKIRREPRHLAI 216 +++GFY +Y + E + A+TQFEP AAR AFPCFDEPAFKA+F IKI R+ ++ A+ Sbjct: 146 SSYYGFYGFSYTDESNEKKYFAATQFEPLAARSAFPCFDEPAFKATFIIKIIRDEQYTAL 205 Query: 217 SNMPLVKSVTVAEGLIEDHFDVTVKMSTYLVAFIISDFESVSKITKSGVKVSVYAVPDKI 276 SNMP SV + +GL++D F +VKMSTYLVAFI+ + +++S+ +G VS+YAVP+KI Sbjct: 206 SNMPKKSSVVLDDGLVQDEFSESVKMSTYLVAFIVGEMKNLSQDV-NGTLVSIYAVPEKI 264 Query: 277 NQADYALDAAVTLLEFYEDYFSIPYPLPKQDLAAIPDFQSGAMENWGLTTYRESALLFDA 336 Q YAL+ V LLEF+++YF I YPL K DL AIPDF++GAMENWGL T+RE LL+D+ Sbjct: 265 GQVHYALETTVKLLEFFQNYFEIQYPLKKLDLVAIPDFEAGAMENWGLLTFREETLLYDS 324 Query: 337 EKSSASSKLGITMTVAHELAHQWFGNLVTMEWWNDLWLNEGFAKFMEFVSVSVTHPELKV 396 SS + + +T +AHELAHQWFGNLVTM+WWNDLWLNEGFA FME+ S+ EL Sbjct: 325 NTSSMADRKLVTKIIAHELAHQWFGNLVTMKWWNDLWLNEGFATFMEYFSLEKIFKELSS 384 Query: 397 GDYFFGKCFDAMEVDALNSSHPVSTPVENPAQIREMFDDVSYDKGACILNMLREYLSADA 456 + F F M+ D+LNSSHP+S+ V++ QI EMFD +SY KG+ +L ML+ YLS D Sbjct: 385 YEDFLDARFKTMKKDSLNSSHPISSSVQSSEQIEEMFDSLSYFKGSSLLLMLKTYLSEDV 444 Query: 457 FKSGIVQYLQKHSYKNTKNEDLWDSMASICPTDGVKGMDGFCSRSQHSSSSSHWHQEGVD 516 F+ +V YL HSY + +++DLWDS + + +D Sbjct: 445 FQHAVVLYLHNHSYASIQSDDLWDSFNEVT-------------------------NQTLD 479 Query: 517 VKTMMNTWTLQKGFPLITITVRGRNVHMKQEHY---MKGSDGAPDTGYLWHVPLTFIT-- 571 VK MM TWTLQKGFPL+T+ +G+ + ++QE + MK DT YLWH+PL+++T Sbjct: 480 VKRMMKTWTLQKGFPLVTVQKKGKELFIQQERFFLNMKPEIQPSDTSYLWHIPLSYVTEG 539 Query: 572 ---SKSDMVHRFLLKTKTDVLILPEEVEWIKFNVGMNGYYIVHYEDDGWDSLTGLLKGTH 628 SK V LL K+ V+ L EEV W+K N+ MNGYYIVHY DD W++L LK Sbjct: 540 RNYSKYQSVS--LLDKKSGVINLTEEVLWVKVNINMNGYYIVHYADDDWEALIHQLKINP 597 Query: 629 TAVSSNDRASLINNAFQLVSIGKLSIEKALDLSLYLKHETEIMPVFQGLNELIPMYKLME 688 +S DRA+LINN F+L +GK+ +++A DL YL +E P+ + L + +Y L+E Sbjct: 598 YVLSDKDRANLINNIFELAGLGKVPLKRAFDLINYLGNENHTAPITEALFQTDLIYNLLE 657 Query: 689 KRDMNEVETQFKAFLIRLLRDLIDKQTWTDEGSVSERMLRSQLLLLACVHNYQPCVQRAE 748 K ++ ++ + +LL++ I +QTWTDEG+ S R LRS LL AC HN C A Sbjct: 658 KLGYMDLASRLVTRVFKLLQNQIQQQTWTDEGTPSMRELRSALLEFACTHNLGNCSTTAM 717 Query: 749 GYFRKWKESNGNLSLPVDVTLAVFAVGAQSTEGWDFLYSKYQFSLSSTEKSQIEFALCRT 808 F W SNG SLP DV VF VGA++ +GW FL KY S EK++I AL + Sbjct: 718 KLFDDWMASNGTQSLPTDVMTTVFKVGAKTDKGWSFLLGKYISIGSEAEKNKILEALASS 777 Query: 809 QNKEKLQWLLDESFKGDKIKTQEFPQILTLIGRNPVGYPLAWQFLRKNWNKLVQKFELGS 868 ++ KL WL+ S GD +TQ+ I+ +GR+ G+ LAW F+++NWNKLVQKF LGS Sbjct: 778 EDVRKLYWLMKSSLNGDNFRTQKLSFIIRTVGRHFPGHLLAWDFVKENWNKLVQKFPLGS 837 Query: 869 SSIAHMVMGTTNQFSTRTRLEEVKGFFSSLKENGSQLRCVQQTIETIEENIGWMDKNFDK 928 +I ++V G+T FST+T L EV+ FF + E +LRCVQ+ +E I+ NI WM+KN Sbjct: 838 YTIQNIVAGSTYLFSTKTHLSEVQAFFENQSEATFRLRCVQEALEVIQLNIQWMEKNLKS 897 Query: 929 IRVWLQSE 936 + WL++E Sbjct: 898 LTWWLRTE 905 >4KXA-A nrPDB Length = 888 Score = 509 bits (1312), Expect = e-144, Method: Compositional matrix adjust. Identities = 302/905 (33%), Positives = 488/905 (53%), Gaps = 62/905 (6%) Query: 49 WNKIRLPEYVIPVHYDLLIHANLTTLTFWGTTKVEITASQPTSTIILHSHHLQISR-ATL 107 W RLP++V PVHYDL + L T+ GT + I S PT + LH +I+R L Sbjct: 13 WKNFRLPDFVNPVHYDLHVKPLLEEDTYTGTVSISINLSAPTRYLWLHLRETRITRLPEL 72 Query: 108 RKGAGERLSEEPLQVLEHPRQEQIALLAPEPLLV----GLPYTVVIHYAGNLSETFHGFY 163 ++ +G+++ + + E+ +QE + + A E L GL Y + + +AG L+ + GFY Sbjct: 73 KRPSGDQV--QVRRCFEYKKQEYVVVEAEEELTPSSGDGL-YLLTMEFAGWLNGSLVGFY 129 Query: 164 KSTYRTKEGELRILASTQFEPTAARMAFPCFDEPAFKASFSIKIRREPRHLAISNMPLVK 223 ++TY T+ G ++ +A+T EPT AR +FPCFDEP KA+++I I + A+SNMP+ K Sbjct: 130 RTTY-TENGRVKSIAATDHEPTDARKSFPCFDEPNKKATYTISITHPKEYGALSNMPVAK 188 Query: 224 SVTVAEGLIEDHFDVTVKMSTYLVAFIISDFESVSKITKSGVKVSVYAVPDKINQADYAL 283 +V + F+ +V MSTYLV F + F+SV +I+ SG +++Y P++ + A+YA Sbjct: 189 EESVDDKWTRTTFEKSVPMSTYLVCFAVHQFDSVKRISNSGKPLTIYVQPEQKHTAEYAA 248 Query: 284 DAAVTLLEFYEDYFSIPYPLPKQDLAAIPDFQSGAMENWGLTTYRESALLFDAEKSSASS 343 + ++ +++E+YF++ Y LPK D AIPDF +GAMENWGL TYRE+ LL+D ++S++S+ Sbjct: 249 NITKSVFDYFEEYFAMNYSLPKLDKIAIPDFGTGAMENWGLITYRETNLLYDPKESASSN 308 Query: 344 KLGITMTVAHELAHQWFGNLVTMEWWNDLWLNEGFAKFMEFVSVSVTHPELKVGD-YFFG 402 + + VAHEL HQWFGN+VTM+WW DLWLNEGFA F EF+ V+ + ++ D Sbjct: 309 QQRVATVVAHELVHQWFGNIVTMDWWEDLWLNEGFASFFEFLGVNHAETDWQMRDQMLLE 368 Query: 403 KCFDAMEVDALNSSHPVSTPVENPAQIREMFDDVSYDKGACILNMLREYLSADAFKSGIV 462 E D+L SSHP+ V P +I +FD +SY KG+ IL ML +++ + F+ G Sbjct: 369 DVLPVQEDDSLMSSHPIIVTVTTPDEITSVFDGISYSKGSSILRMLEDWIKPENFQKGCQ 428 Query: 463 QYLQKHSYKNTKNEDLWDSM--ASICPTDGVKGMDGFCSRSQHSSSSSHWHQEGVDVKTM 520 YL+K+ +KN K D W ++ AS P VK + Sbjct: 429 MYLEKYQFKNAKTSDFWAALEEASRLP-----------------------------VKEV 459 Query: 521 MNTWTLQKGFPLITITVRGRNVHMKQ---EHYMKGSDGAPDTGYLWHVPLTFITSKSDMV 577 M+TWT Q G+P++ + +N+ K+ + S D GY W++P+ + Sbjct: 460 MDTWTRQMGYPVLNVN-GVKNITQKRFLLDPRANPSQPPSDLGYTWNIPVKWTEDNITSS 518 Query: 578 HRFLLKTKTDVLI---LPEEVEWIKFNVGMNGYYIVHYEDDGWDSLTGLLKGTHTAVSSN 634 F K + + P ++K N G+Y V+YE WDS+ L H SS Sbjct: 519 VLFNRSEKEGITLNSSNPSGNAFLKINPDHIGFYRVNYEVATWDSIATALSLNHKTFSSA 578 Query: 635 DRASLINNAFQLVSIGKLSIEKALDLSLYLKHETEIMP---VFQGLNELIPMYKLMEKRD 691 DRASLI++AF L L + AL+L+ YLK E +P V + +I M++ D Sbjct: 579 DRASLIDDAFALARAQLLDYKVALNLTKYLKREENFLPWQRVISAVTYIISMFE-----D 633 Query: 692 MNEVETQFKAFLIRLLRDLIDKQTWTDEGSVSERMLRSQLLLLACVHNYQPCVQRAEGYF 751 E+ + + ++ + D W D G ++LRS +L AC + + A F Sbjct: 634 DKELYPMIEEYFQGQVKPIADSLGWNDAGDHVTKLLRSSVLGFACKMGDREALNNASSLF 693 Query: 752 RKWKESNGNLSLPVDVTLAVFAVGAQSTEG---WDFLYSKYQFSLSSTEKSQIEFALCRT 808 +W NG +SLPV++ L V+ G Q++ W++ +YQ + + EK ++ + L Sbjct: 694 EQWL--NGTVSLPVNLRLLVYRYGMQNSGNEISWNYTLEQYQKTSLAQEKEKLLYGLASV 751 Query: 809 QNKEKLQWLLDESFKGDKIKTQEFPQILTLIGRNPVGYPLAWQFLRKNWNKLVQKFELGS 868 +N L LD + IKTQ+ ++ I N G +AW +++ NW+ LV ++ L + Sbjct: 752 KNVTLLSRYLDLLKDTNLIKTQDVFTVIRYISYNSYGKNMAWNWIQLNWDYLVNRYTLNN 811 Query: 869 SSIAHMVMGTTNQFSTRTRLEEVKGFFSSLKENGSQLRCVQQTIETIEENIGWMDKNFDK 928 ++ +V F+T +L +++ FF+ + G+ + +Q +ET++ NI W+ ++ + Sbjct: 812 RNLGRIVT-IAEPFNTELQLWQMESFFAKYPQAGAGEKPREQVLETVKNNIEWLKQHRNT 870 Query: 929 IRVWL 933 IR W Sbjct: 871 IREWF 875 >5LG6-A nrPDB Length = 968 Score = 492 bits (1267), Expect = e-139, Method: Compositional matrix adjust. Identities = 312/935 (33%), Positives = 486/935 (51%), Gaps = 90/935 (9%) Query: 48 PWNKIRLPEYVIPVHYDLLIHANLTT-----LTFWGTTKVEITASQPTSTIILHSHHLQI 102 PWN+ RLP ++P Y++ + LT F G + V +PT II+HS L Sbjct: 48 PWNRYRLPTTLLPDSYNVTLRPYLTPNADGLYIFKGKSIVRFICQEPTDVIIIHSKKLNY 107 Query: 103 S---RATLRKGAGERLSEEPLQVLEHPRQEQIALLAPEPLLVGLP--------YTVVIHY 151 + + +G G+ QV E R E + L E L+V L Y + + Sbjct: 108 TTQGHMVVLRGVGDS------QVPEIDRTELVELT--EYLVVHLKGSLQPGHMYEMESEF 159 Query: 152 AGNLSETFHGFYKSTYRTKEGELR-ILASTQFEPTAARMAFPCFDEPAFKASFSIKIRRE 210 G L++ GFY+S Y EG ++ +LA+TQ + T AR +FPCFDEPA KA+F+I + Sbjct: 160 QGELADDLAGFYRSEYM--EGNVKKVLATTQMQSTDARKSFPCFDEPAMKATFNITLIHP 217 Query: 211 PRHLAISNMPLVKSVTVAEGLIED------HFDVTVKMSTYLVAFIISDFESVSKITKSG 264 A+SNMP S T L ED F+ T MSTYL+A+I+S+F+SV++ ++G Sbjct: 218 NNLTALSNMPPKGSST---PLAEDPNWSVTEFETTPVMSTYLLAYIVSEFQSVNETAQNG 274 Query: 265 VKVSVYAVPDKINQAD--YALDAAVTLLEFYEDYFSIPYPLPKQDLAAIPDFQSGAMENW 322 V + ++A P+ I + YAL+ +L F+ ++++ YPLPK D A+PDF +GAMENW Sbjct: 275 VLIRIWARPNAIAEGHGMYALNVTGPILNFFANHYNTSYPLPKSDQIALPDFNAGAMENW 334 Query: 323 GLTTYRESALLFDAEKSSASSKLGITMTVAHELAHQWFGNLVTMEWWNDLWLNEGFAKFM 382 GL TYRE+ALLFD + SS S+K + +AHELAHQWFGNLVT+ WWNDLWLNEGFA ++ Sbjct: 335 GLVTYRENALLFDPQSSSISNKERVVTVIAHELAHQWFGNLVTLAWWNDLWLNEGFASYV 394 Query: 383 EFVSVSVTHPELKVGDYFF-GKCFDAMEVDALNSSHPVSTPVE---NPAQIREMFDDVSY 438 E++ P + D G + M VDAL SSHP++TP E PAQI EMFD +SY Sbjct: 395 EYLGADHAEPTWNLKDLIVPGDVYRVMAVDALASSHPLTTPAEEVNTPAQISEMFDSISY 454 Query: 439 DKGACILNMLREYLSADAFKSGIVQYLQKHSYKNTKNEDLWDSMASICPTDGVKGMDGFC 498 KGA ++ ML +L+ D FK G+ YL +Y+NT DLW+ + K +D Sbjct: 455 SKGASVIRMLSNFLTEDLFKEGLASYLHAFAYQNTTYLDLWEHLQ--------KAVDAQT 506 Query: 499 SRSQHSSSSSHWHQEGVDVKTMMNTWTLQKGFPLITITVRGRNVHMKQEHYMKGSDG--- 555 S + V+ +M+ WTLQ GFP+IT+ + N+ Q+H++ S+ Sbjct: 507 SIRLPDT-----------VRAIMDRWTLQMGFPVITVDTKTGNI--SQKHFLLDSESNVT 553 Query: 556 -APDTGYLWHVPLTFITSKSDMVHRFL--LKTKTDVLILPEEVEWIKFNVGMNGYYIVHY 612 + YLW VP++ I + H +L + + L +W+ NV + GY+ V+Y Sbjct: 554 RSSAFDYLWIVPISSIKNGVMQDHYWLRDVSQAQNDLFKTASDDWVLLNVNVTGYFQVNY 613 Query: 613 EDDGWDSLTGLLKGTHTAVSSNDRASLINNAFQLVSIGKLSIEKALDLSLYLKHETEIMP 672 ++D W + L+ + + +RA +I ++F L + + + ALD +L+L E E MP Sbjct: 614 DEDNWRMIQHQLQTNLSVIPVINRAQVIYDSFNLATAHMVPVTLALDNTLFLNGEKEYMP 673 Query: 673 VFQGLNELIPMYKLMEKRDMNEVETQFKAFLIRLLRDLIDK-----QTWTDEG-SVSERM 726 L+ L + LM R +EV K +L + + L + WT+ ++ ++ Sbjct: 674 WQAALSSL-SYFSLMFDR--SEVYGPMKKYLRKQVEPLFQHFETLTKNWTERPENLMDQY 730 Query: 727 LRSQLLLLACVHNYQPCVQRAEGYFRKWKESNGNLSLPVDVTLAVF--AVGAQSTEGWDF 784 + AC + C A+ F +W N + ++ ++ A+ + WDF Sbjct: 731 SEINAISTACSNGLPQCENLAKTLFDQWMSDPENNPIHPNLRSTIYCNAIAQGGQDQWDF 790 Query: 785 LYSKYQFSLSSTEKSQIEFALCRTQNKEKLQWLLDESFKGDKIKTQEFPQILTLIGRNPV 844 + + Q + E ++ AL + L L + D I+ Q+ + I N + Sbjct: 791 AWGQLQQAQLVNEADKLRSALACSNEVWLLNRYLGYTLNPDLIRKQDATSTINSIASNVI 850 Query: 845 GYPLAWQFLRKNWNKLVQKFELGSSSIAHMVMGTTNQFSTRTRLEEVKGFFSSLKEN--- 901 G PLAW F++ NW KL Q + GS S ++++ G T +FS+ L++++ F K+N Sbjct: 851 GQPLAWDFVQSNWKKLFQDYGGGSFSFSNLIQGVTRRFSSEFELQQLEQF----KKNNMD 906 Query: 902 ---GSQLRCVQQTIETIEENIGWMDKNFDKIRVWL 933 GS R ++Q +E + NI W+ +N + + W Sbjct: 907 VGFGSGTRALEQALEKTKANIKWVKENKEVVLNWF 941 >5LHD-A nrPDB Length = 950 Score = 491 bits (1264), Expect = e-139, Method: Compositional matrix adjust. Identities = 315/946 (33%), Positives = 479/946 (50%), Gaps = 71/946 (7%) Query: 27 STPSWCQSTEASPKRSDGTPFPWNKIRLPEYVIPVHYDLLIHANLTT-----LTFWGTTK 81 +TPS +T + + WN+ RLP + P Y + + LT F G++ Sbjct: 32 TTPSASATTNPASATTLDQSKAWNRYRLPNTLKPDSYRVTLRPYLTPNDRGLYVFKGSST 91 Query: 82 VEITASQPTSTIILHSHHL-----QISRATLRKGAGERLSEEPLQVLEHPRQEQIALLAP 136 V T + T II+HS L Q R LR G + + L P + + L Sbjct: 92 VRFTCKEATDVIIIHSKKLNYTLSQGHRVVLRGVGGSQPPDIDKTELVEPTEYLVVHLKG 151 Query: 137 EPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELR-ILASTQFEPTAARMAFPCFD 195 L+ Y + + G L++ GFY+S Y EG +R ++A+TQ + AR +FPCFD Sbjct: 152 S-LVKDSQYEMDSEFEGELADDLAGFYRSEYM--EGNVRKVVATTQMQAADARKSFPCFD 208 Query: 196 EPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGLIED------HFDVTVKMSTYLVAF 249 EPA KA F+I + A+SNM L K + L ED F T KMSTYL+AF Sbjct: 209 EPAMKAEFNITLIHPKDLTALSNM-LPKGPSTP--LPEDPNWNVTEFHTTPKMSTYLLAF 265 Query: 250 IISDFESVSKITKSGVKVSVYAVPDKI--NQADYALDAAVTLLEFYEDYFSIPYPLPKQD 307 I+S+F+ V K +GV + ++A P I DYAL+ +L F+ ++ PYPLPK D Sbjct: 266 IVSEFDYVEKQASNGVLIRIWARPSAIAAGHGDYALNVTGPILNFFAGHYDTPYPLPKSD 325 Query: 308 LAAIPDFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVAHELAHQWFGNLVTME 367 +PDF +GAMENWGL TYRE++LLFD SS+S+K + +AHELAHQWFGNLVT+E Sbjct: 326 QIGLPDFNAGAMENWGLVTYRENSLLFDPLSSSSSNKERVVTVIAHELAHQWFGNLVTIE 385 Query: 368 WWNDLWLNEGFAKFMEFVSVSVTHPELKVGDYF-FGKCFDAMEVDALNSSHPVSTP---V 423 WWNDLWLNEGFA ++E++ P + D + M VDAL SSHP+STP + Sbjct: 386 WWNDLWLNEGFASYVEYLGADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSTPASEI 445 Query: 424 ENPAQIREMFDDVSYDKGACILNMLREYLSADAFKSGIVQYLQKHSYKNTKNEDLWDSMA 483 PAQI E+FD +SY KGA +L ML +LS D FK G+ YL +Y+NT +LWD + Sbjct: 446 NTPAQISELFDAISYSKGASVLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYLNLWDHLQ 505 Query: 484 SICPTDGVKGMDGFCSRSQHSSSSSHWHQEGVDVKTMMNTWTLQKGFPLITI-TVRGRNV 542 + Q V+ +MN WTLQ GFP+IT+ T G Sbjct: 506 EAVNNRSI--------------------QLPTTVRDIMNRWTLQMGFPVITVDTSTGT-- 543 Query: 543 HMKQEHYMKGSDG----APDTGYLWHVPLTFITSKSDMVHRFLLKTKT-DVLILPEEVEW 597 + QEH++ D + Y+W VP+T I +L+ + + L EW Sbjct: 544 -LSQEHFLLDPDSNVTRPSEFNYVWIVPITSIRDGRQQQDYWLIDVRAQNDLFSTSGNEW 602 Query: 598 IKFNVGMNGYYIVHYEDDGWDSLTGLLKGTHTAVSSNDRASLINNAFQLVSIGKLSIEKA 657 + N+ + GYY V+Y+++ W + L+ H+A+ +RA +IN+AF L S K+ + A Sbjct: 603 VLLNLNVTGYYRVNYDEENWRKIQTQLQRDHSAIPVINRAQIINDAFNLASAHKVPVTLA 662 Query: 658 LDLSLYLKHETEIMPVFQGLNELIPMYKLMEKRDMNEVETQFKAFLIRLLRDLI-----D 712 L+ +L+L E + MP L+ L +KLM D +EV K +L + + L + Sbjct: 663 LNNTLFLIEERQYMPWEAALSSL-SYFKLM--FDRSEVYGPMKNYLKKQVTPLFIHFRNN 719 Query: 713 KQTWTD-EGSVSERMLRSQLLLLACVHNYQPCVQRAEGYFRKWKESNGNLSLPVDVTLAV 771 W + ++ ++ + AC + C + G F++W E+ N + ++ V Sbjct: 720 TNNWREIPENLMDQYSEVNAISTACSNGVPECEEMVSGLFKQWMENPNNNPIHPNLRSTV 779 Query: 772 F--AVGAQSTEGWDFLYSKYQFSLSSTEKSQIEFALCRTQNKEKLQWLLDESFKGDKIKT 829 + A+ E WDF + +++ + E ++ AL ++ L L + D I+ Sbjct: 780 YCNAIAQGGEEEWDFAWEQFRNATLVNEADKLRAALACSKELWILNRYLSYTLNPDLIRK 839 Query: 830 QEFPQILTLIGRNPVGYPLAWQFLRKNWNKLVQKFELGSSSIAHMVMGTTNQFSTRTRLE 889 Q+ + I N +G L W F++ NW KL + GS S ++++ T +FST L+ Sbjct: 840 QDATSTIISITNNVIGQGLVWDFVQSNWKKLFNDYGGGSFSFSNLIQAVTRRFSTEYELQ 899 Query: 890 EVKGFFSSLKEN--GSQLRCVQQTIETIEENIGWMDKNFDKIRVWL 933 +++ F +E GS R ++Q +E + NI W+ +N + + W Sbjct: 900 QLEQFKKDNEETGFGSGTRALEQALEKTKANIKWVKENKEVVLQWF 945 >4WZ9-A nrPDB Length = 957 Score = 380 bits (976), Expect = e-105, Method: Compositional matrix adjust. Identities = 258/795 (32%), Positives = 391/795 (49%), Gaps = 64/795 (8%) Query: 51 KIRLPEYVIPVHYDLL----IHANLTTLTFWGTTKVEITASQPTSTIILHSHHLQISRAT 106 + RLP IP+HYDL IH N T T GT +++ Q T +++H+ L +S A Sbjct: 45 RYRLPTTSIPIHYDLHLRTEIHRNERTFT--GTVGIQLQVVQATDKLVMHNRGLVMSSAK 102 Query: 107 LRK------GAGERLSEEPLQVLEHPRQEQIALLAPEPLLVGLPYTVVIHYAGNLSETFH 160 + GA + + +Q E I +P L G Y + + + G L+ Sbjct: 103 VSSLPNGVTGAPTLIGD--VQYSTDTTFEHITFTSPTILQPGT-YLLEVAFQGRLATNDD 159 Query: 161 GFYKSTYRTKEGELRILASTQFEPTAARMAFPCFDEPAFKASFSIKIRREPRHLAISNMP 220 GFY S+Y GE R LA+TQFE T+ARMAFPC+DEP KA+F++ I + AISNMP Sbjct: 160 GFYVSSYVADNGERRYLATTQFESTSARMAFPCYDEPGLKATFTVSITHSLSYKAISNMP 219 Query: 221 LVKSVTVAEGLIEDHFDVTVKMSTYLVAFIISDFESVSKITKSGVKVSVYAVPDKINQAD 280 + + + F+ T MSTYL+AF++SDF+ + SG + VY P+ N+A Sbjct: 220 QKTTTDIETDMRTTFFEKTPAMSTYLLAFVVSDFQ----LRLSGAQ-RVYVRPNAFNEAT 274 Query: 281 YALDAAVTLLEFYEDYFSIPYP--LPKQDLAAIPDFQSGAMENWGLTTYRESALLFDAEK 338 +AL+A V +L+ +D+ IPY +PK D AIPDF +GAMENWGL TYRE ALLF+ Sbjct: 275 FALEAGVKILKVLDDHLGIPYDTYMPKLDQIAIPDFAAGAMENWGLVTYREQALLFNPAV 334 Query: 339 SSASSKLGITMTVAHELAHQWFGNLVTMEWWNDLWLNEGFAKFMEFVSVSVTHPELKVGD 398 S+ K + T+AHE AHQWFGNLV+ EWW +WLNEGFA EF ++ + +P + + Sbjct: 335 STYRGKTNVATTIAHEYAHQWFGNLVSPEWWEYIWLNEGFATLYEFYALDMAYPGQEYWE 394 Query: 399 YFFGKCFD-AMEVDALNSSHPVSTPVENPAQIREMFDDVSYDKGACILNMLREYLSADAF 457 F + AM D S+ P++ P +I +FD V+YDK +LNM+R L D + Sbjct: 395 LFNQQVIQYAMGQDGQASTRPMNWNAATPGEISALFDRVAYDKSGSVLNMMRHVLGDDNW 454 Query: 458 KSGIVQYLQKHSYKNTKNEDLWDSMASICPTDGVKGMDGFCSRSQHSSSSSHWHQEGVDV 517 K+G+ YL + + +E L+ + S GV GV V Sbjct: 455 KAGLKAYLTDRALQGAVDEQLYAGLQSAIEGKGVL-------------------PNGVTV 495 Query: 518 KTMMNTWTLQKGFPLITI--TVRGRNVHMKQEHYMKGSDGAPDTGYLWHVPLTFITSKSD 575 +M TWT + G+P++ + + +V + QE + P+T +W +P ++ Sbjct: 496 AQIMRTWTNEAGYPVLNVRRSYDTGDVIISQERFYNDRK-VPNTN-IWMIPYNYVHQAKA 553 Query: 576 MVHRF----LLKTKTDVL--ILPEEVEWIKFNVGMNGYYIVHYEDDGWDSLTGLLKGTHT 629 + F L TK + +P EWI FN GYY V+Y++ W+ +T L Sbjct: 554 DFNEFDDFQWLATKAARIETTVPAN-EWIVFNKQQVGYYRVNYDEHNWELITNALHENWA 612 Query: 630 AVSSNDRASLINNAFQLVSIGKLSIEKALDLSLYLKHETEIMPVFQGLNELIPMYKLMEK 689 ++ +RA LI++A+ L G+L + AL YL++E E P + N + + Sbjct: 613 SIHRLNRAQLIDDAYWLARSGRLDLRVALRFMTYLRNEREYAP-WTAANVALTYFN-NRL 670 Query: 690 RDMNEVETQFKAFLIRLLRDLIDKQTWTDEGSVSERMLRSQLLLL----ACVHNYQPCVQ 745 R E F F+ L+ D+ T D S + +L L+ AC Y C+ Sbjct: 671 RGTAEYH-NFLIFVDALIEDIYSLLT-IDAVSPDDTLLHKYLVQTISTWACSMGYTDCLM 728 Query: 746 RAEGYFRKWKESNGNLSLPVDVTLAVFAVGAQST--EGWDFLYSKYQFSLSSTEKSQIEF 803 + + G P D+ + G +S + +LY K S + E++ + Sbjct: 729 KTAALLKAEASGTGPAVHP-DIASVTYCYGMRSALESEFQYLYRKMMNSKNLAERTMLID 787 Query: 804 ALCRTQNKEKLQWLL 818 +L + NKE L+ L Sbjct: 788 SLGCSNNKEFLKAFL 802 >1Z1W-A nrPDB Length = 780 Score = 295 bits (755), Expect = 7e-80, Method: Compositional matrix adjust. Identities = 192/594 (32%), Positives = 292/594 (49%), Gaps = 73/594 (12%) Query: 63 YDLLIHANLTTLTFWGTTKVEITASQPTSTIILHSHHLQISRATLRKGAGERLSEEPLQV 122 YDL + ++ TF GT + A I+L + LQI+ + G + + Q Sbjct: 6 YDLTLDFDIQKRTFNGTETITADAGD----IVLDAVGLQINWMKV-NGRDTAFTYDG-QT 59 Query: 123 LEHPRQEQIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRILASTQF 182 + P Q P + I +AG +S++ G Y + G + +T F Sbjct: 60 VRAPGDSQ-------------PQKIEISFAGKVSDSLSGIYYA------GRENGMITTHF 100 Query: 183 EPTAARMAFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGLIEDHFDVTVKM 242 E T AR FPC D PA+KA F+I + + + AISNMP K + V+E + + F T +M Sbjct: 101 EATDARRMFPCVDHPAYKAVFAITVVIDKDYDAISNMP-PKRIEVSERKVVE-FQDTPRM 158 Query: 243 STYLVAFIISDFESVSKITKSGVKVSVYAVPDKINQADYALDAAVTLLEFYEDYFSIPYP 302 STYL+ I F + + + + K ++ Y LD A +EFYE+YF IPY Sbjct: 159 STYLLYVGIGKFRYEYEKYRD---IDLILASLKDIRSKYPLDMARKSVEFYENYFGIPYA 215 Query: 303 LPKQDLAAIPDFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVAHELAHQWFGN 362 LPK L ++P+F +GAMENWG T+RE + AE S+ + K +AHE+AHQWFG+ Sbjct: 216 LPKMHLISVPEFGAGAMENWGAITFREIYMDI-AENSAVTVKRNSANVIAHEIAHQWFGD 274 Query: 363 LVTMEWWNDLWLNEGFAKFMEFVSVSVTHPELKV-GDYFFGKCFDAMEVDALNSSHPVST 421 LVTM+WWNDLWLNE FA FM + ++ PE GD+F + A+ D+L ++HP+ Sbjct: 275 LVTMKWWNDLWLNESFATFMSYKTMDTLFPEWSFWGDFFVSRTSGALRSDSLKNTHPIEV 334 Query: 422 PVENPAQIREMFDDVSYDKGACILNMLREYLSADAFKSGIVQYLQKHSYKNTKNEDLWDS 481 V +P +I ++FD++SY KGA IL M+ +Y + F+ GI +YL H + N + DLW + Sbjct: 335 DVRDPDEISQIFDEISYGKGASILRMIEDYAGYEEFRKGISKYLNDHKFGNAEGSDLWTA 394 Query: 482 MASICPTDGVKGMDGFCSRSQHSSSSSHWHQEGVDVKTMMNTWTLQKGFPLITITVRGRN 541 + + G VK +M W G+P+I + GR Sbjct: 395 IEDVS---------------------------GKPVKRVMEYWIKNPGYPVIKLKRNGRK 427 Query: 542 VHMKQEHYMKGSDGAPDTGYLWHVPLTFITSKSDMVHRFLLKTKTDVLILPEEVEWIKFN 601 + M Q ++ + + G W VP+ K D V R LL+ + + E IK N Sbjct: 428 ITMYQTRFLLNGE---EEGR-WPVPVNI--KKKDGVERILLEDEASI----EADGLIKIN 477 Query: 602 VGMNGYYIVHYEDDGWDSLTGLLKGTHTAVSSNDRASLINNAFQLVSIGKLSIE 655 G+Y V Y+D + + G + +S DR L+++ F + G + E Sbjct: 478 ADSAGFYRVLYDDATFSDVM----GHYRDLSPLDRIGLVDDLFAFLLSGHIDPE 527 >5DLL-A nrPDB Length = 867 Score = 118 bits (296), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 109/387 (28%), Positives = 169/387 (43%), Gaps = 28/387 (7%) Query: 114 RLSEEPLQVLEHPRQEQIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGE 173 +L+ + L E E ++ P L V I+ + N S G YKS G+ Sbjct: 75 KLNNKHLSPAEFAVNENQLIINNVPEKFVLQTVVEINPSANTS--LEGLYKS------GD 126 Query: 174 LRILASTQFEPTAARMAFPCFDEPAFKASFSIKIRREPRHLAI--SNMPLVKSVTVAEGL 231 + STQ E T R D P A+F++KI + + I SN + S +++ Sbjct: 127 V---FSTQCEATGFRKITYYLDRPDVMAAFTVKIIADKKKYPIILSNGDKIDSGDISDN- 182 Query: 232 IEDHFDV---TVKMSTYLVAFIISDFESVSK--ITKSGVKVS--VYAVPDKINQADYALD 284 HF V K YL A + D S+ ITKS KVS +YA I++ YA+ Sbjct: 183 --QHFAVWKDPFKKPCYLFALVAGDLASIKDTYITKSQRKVSLEIYAFKQDIDKCHYAMQ 240 Query: 285 AAVTLLEFYEDYFSIPYPLPKQDLAAIPDFQSGAMENWGLTTYRESALLFDAEKSSASSK 344 A +++ ED F + Y L + A+PDF +GAMEN GL + ++ + ++ Sbjct: 241 AVKDSMKWDEDRFGLEYDLDTFMIVAVPDFNAGAMENKGLNIFNTKYIMASNKTATDKDF 300 Query: 345 LGITMTVAHELAHQWFGNLVTMEWWNDLWLNEGFAKF--MEFVSVSVTHPELKVGDYFFG 402 + V HE H W G+ VT W L L EG F EF S + ++ D Sbjct: 301 ELVQSVVGHEYFHNWTGDRVTCRDWFQLSLKEGLTVFRDQEFTSDLNSRDVKRIDDVRII 360 Query: 403 KCFDAMEVDALNSSHPVSTPVENPAQIREMFDDVSYDKGACILNMLREYLSADAFKSGIV 462 + E DA SHP+ E+ ++ + Y+KGA I+ M+ L + F+ G+ Sbjct: 361 RSAQFAE-DASPMSHPIRP--ESYIEMNNFYTVTVYNKGAEIIRMIHTLLGEEGFQKGMK 417 Query: 463 QYLQKHSYKNTKNEDLWDSMASICPTD 489 Y ++H + +D ++MA D Sbjct: 418 LYFERHDGQAVTCDDFVNAMADANNRD 444 >5Y1X-A nrPDB Length = 914 Score = 104 bits (259), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 93/354 (26%), Positives = 149/354 (42%), Gaps = 41/354 (11%) Query: 147 VVIHYAGNLSETFHGFYKSTYRTKEGELRILASTQFEPTAARMAFPCFDEPAFKASFSIK 206 V+IH N + T G YKS + + +Q E T R D P A + + Sbjct: 123 VIIHPETNYALT--GLYKS---------KNIIVSQCEATGFRRITFFIDRPDMMAKYDVT 171 Query: 207 IR--REPRHLAISNMPLVKSVTVAEGLIEDHFDVTVKMSTYLVAFIISDFESVS-----K 259 + +E + +SN V + G F+ YL A + D + +S K Sbjct: 172 VTADKEKYPVLLSNGDKVNEFEIPGGRHGARFNDPHLKPCYLFAVVAGDLKHLSATYITK 231 Query: 260 ITKSGVKVSVYAVPDKINQADYALDAAVTLLEFYEDYFSIPYPLPKQDLAAIPDFQSGAM 319 TK V++ V++ +++ +AL+ + F EDYF + Y L + +L A+ DF GAM Sbjct: 232 YTKKKVELYVFSEEKYVSKLQWALECLKKSMAFDEDYFGLEYDLSRLNLVAVSDFNVGAM 291 Query: 320 ENWGLTTYRESALLFDAEKSSASSKLGITMTVAHELAHQWFGNLVTMEWWNDLWLNEGFA 379 EN GL + ++LL + S S I V HE H + GN VT+ W L L EG Sbjct: 292 ENKGLNIFNANSLLASKKNSIDFSYARILTVVGHEYFHNYTGNRVTLRDWFQLTLKEGLT 351 Query: 380 ---------KFMEFVSVSVTHPELKVGDYFFGKCFDAMEVDALNSSHPVSTPV--ENPAQ 428 + + V+ ++H +L V L S P+S P+ E+ Sbjct: 352 VHRENLFSEEMTKTVTTRLSHVDL------------LRSVQFLEDSSPLSHPIRPESYVS 399 Query: 429 IREMFDDVSYDKGACILNMLREYLSADAFKSGIVQYLQKHSYKNTKNEDLWDSM 482 + + YDKG+ ++ M L + +K G Y++K+ ED +M Sbjct: 400 MENFYTTTVYDKGSEVMRMYLTILGEEYYKKGFDIYIKKNDGNTATCEDFNYAM 453 >4QHP-A nrPDB Length = 870 Score = 92.4 bits (228), Expect = 9e-19, Method: Compositional matrix adjust. Identities = 81/317 (25%), Positives = 133/317 (41%), Gaps = 21/317 (6%) Query: 180 TQFEPTAARMAFPCFDEPAFKASFSIKI----RREPRHLAISNMPLVKSVTVAEGLIEDH 235 TQ EP R D P + F+ I +R P + +SN + ++G Sbjct: 117 TQCEPEGFRKITFYIDRPDVMSKFTTTIVADKKRYP--VLLSNGNKIDGGEFSDGRHWVK 174 Query: 236 FDVTVKMSTYLVAFIISDF----ESVSKITKSGVKVSVYAVPDKINQADYALDAAVTLLE 291 ++ +YL A + D + + ++ VK+ Y + +A+++ ++ Sbjct: 175 WEDPFSKPSYLFALVAGDLAVTEDYFTTMSGRNVKIEFYTTEADKPKVGFAVESLKNAMK 234 Query: 292 FYEDYFSIPYPLPKQDLAAIPDFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTV 351 + E F + Y L + A+ DF GAMEN GL + +L D+ ++ + GI V Sbjct: 235 WDETRFGLEYDLDIFMVVAVGDFNMGAMENKGLNIFNTKFVLADSRTATDTDFEGIESVV 294 Query: 352 AHELAHQWFGNLVTMEWWNDLWLNEGFAKF--MEFVSVSVTHPELKVGDYFFGKCFDAME 409 HE H W GN VT W L L EG F EF + ++ + + E Sbjct: 295 GHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSGDRASRAVRRIENIRLLRQHQFPE 354 Query: 410 VDALNSSHPVSTPVENPAQIREM---FDDVSYDKGACILNMLREYLSADAFKSGIVQYLQ 466 DA ++HPV PA EM + Y+KGA ++ M L + F+ G+ Y Q Sbjct: 355 -DAGPTAHPV-----RPASYEEMNNFYTMTVYEKGAEVVRMYHTLLGEEGFQKGMKLYFQ 408 Query: 467 KHSYKNTKNEDLWDSMA 483 +H + +D +MA Sbjct: 409 RHDGQAVTCDDFRAAMA 425 >4GAA-A nrPDB Length = 609 Score = 88.6 bits (218), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 76/325 (23%), Positives = 140/325 (43%), Gaps = 45/325 (13%) Query: 172 GELRILASTQFEPTAARMAFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGL 231 G++ +Q + T R PC D P+ K ++ ++ +A+ M ++ ++E Sbjct: 122 GKIHPYLFSQCQATHCRSIIPCQDTPSVKFTYYSQVSVPKELMAL--MSALRDGELSEQS 179 Query: 232 IEDH----FDVTVKMSTYLVAFIISDFESVSKITKSGVKVSVYAVPDKINQADYALDAAV 287 + F V + +YL+A ++ E K G + +++ + + + Y Sbjct: 180 DSNRKIYRFKQNVPIPSYLIALVVGALEG----RKVGPRTTIWTEKELLEPSVYEFAETE 235 Query: 288 TLLEFYEDYFSIPYPLPKQDLAAIP-DFQSGAMENWGLTTYRESALLFDAEKSSASSKLG 346 +L++ ED + PY + DL +P F G MEN LT + L D +S Sbjct: 236 KMLKYAED-LAGPYVWGQYDLLILPPSFPYGGMENPCLTFVTPTVLAGDRSLASV----- 289 Query: 347 ITMTVAHELAHQWFGNLVTMEWWNDLWLNEGFAKFMEFVSVSVTHPELKVGDYFFGKCFD 406 +AHE++H W GNLVT E W + WLNEG ++ E ++ +G+ F Sbjct: 290 ----IAHEISHSWTGNLVTNETWENFWLNEGHTVYL----------ERRIDGRLYGEEFR 335 Query: 407 AME-----------VDALNSSHPVSTPVEN--PAQIREMFDDVSYDKGACILNMLREYLS 453 + V+ +++P++ V N + F V Y+KG +L L + L Sbjct: 336 QFKALGGWKELQNSVNTFGATNPLTNLVPNLHEVDVDAAFSSVPYEKGFALLFYLEQLLG 395 Query: 454 ADAFKSGIVQ-YLQKHSYKNTKNED 477 G ++ Y+Q ++K+ E+ Sbjct: 396 GPEIFLGFLKSYIQMFAFKSVTTEE 420 >5FWQ-A nrPDB Length = 633 Score = 87.0 bits (214), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 82/326 (25%), Positives = 141/326 (43%), Gaps = 49/326 (15%) Query: 180 TQFEPTAARMAFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGLIED----- 234 +Q + R PC D P+ K +++ ++ P+ L ++ M ++ + ED Sbjct: 148 SQCQAIHCRAILPCQDTPSVKLTYTAEVSV-PKEL-VALMSAIRDGETPDP--EDPSRKI 203 Query: 235 -HFDVTVKMSTYLVAFIISDFESVSKITKSGVKVSVYAVPDKINQADYALDAAVTLLEFY 293 F V + YL+A ++ ES + G + V++ +++ ++ Y ++L+ Sbjct: 204 YKFIQKVPIPCYLIALVVGALES----RQIGPRTLVWSEKEQVEKSAYEFSETESMLKIA 259 Query: 294 EDYFSIPYPLPKQDLAAIP-DFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVA 352 ED PY + DL +P F G MEN LT + L D S+ +A Sbjct: 260 ED-LGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNV---------IA 309 Query: 353 HELAHQWFGNLVTMEWWNDLWLNEGFAKFMEFVSVSVTHPELKVGDYFFG---KCFDAM- 408 HE++H W GNLVT + W+ WLNEG ++ E + FG + F+A+ Sbjct: 310 HEISHSWTGNLVTNKTWDHFWLNEGHTVYL----------ERHICGRLFGEKFRHFNALG 359 Query: 409 -------EVDALNSSHPVSTPVENPAQIRE--MFDDVSYDKGACILNMLREYLSADAFKS 459 V +HP + V + I + V Y+KG +L L + L Sbjct: 360 GWGELQNSVKTFGETHPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFL 419 Query: 460 GIVQ-YLQKHSYKNTKNEDLWDSMAS 484 G ++ Y++K SYK+ +D D + S Sbjct: 420 GFLKAYVEKFSYKSITTDDWKDFLYS 445 >4Q4I-A nrPDB Length = 891 Score = 85.5 bits (210), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 92/374 (24%), Positives = 151/374 (40%), Gaps = 59/374 (15%) Query: 180 TQFEPTAARMAFPCFDEPAFKASFSIKIRRE----PRHLAISNMPLVKSVTVAEGLIED- 234 TQ E R D P A F+ KI + P L+ N VA+G +E+ Sbjct: 139 TQCEAEGFRHITYYLDRPDVLARFTTKIIADKIKYPFLLSNGN-------RVAQGELENG 191 Query: 235 ----HFDVTVKMSTYLVAFIISDFESVSKI--TKSGVKVSVYAVPDK--INQADYALDAA 286 + YL A + DF+ + T+SG +V++ D+ +++A +A+ + Sbjct: 192 RHWVQWQDPFPKPCYLFALVAGDFDVLRDTFTTRSGREVALELYVDRGNLDRAPWAMTSL 251 Query: 287 VTLLEFYEDYFSIPYPLPKQDLAAIPDFQSGAMENWGLTTYRESALLFDAEKSSASSKLG 346 +++ E+ F + Y L + A+ F GAMEN GL + +L + ++ L Sbjct: 252 KNSMKWDEERFGLEYDLDIYMIVAVDFFNMGAMENKGLNIFNSKYVLARTDTATDKDYLD 311 Query: 347 ITMTVAHELAHQWFGNLVTMEWWNDLWLNEGFAKF--MEFVSVSVTHPELKVGDYFFGKC 404 I + HE H W GN VT W L L EG F EF S + ++ + + Sbjct: 312 IERVIGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDLGSRAVNRINNVRTMRG 371 Query: 405 FDAMEVDALNSSHPVSTPVENPAQIREM---FDDVSYDKGACILNMLREYLSADAFKSGI 461 E DA +HP+ P + EM + Y+KGA ++ M+ L + F+ G+ Sbjct: 372 LQFAE-DASPMAHPI-----RPDMVIEMNNFYTLTVYEKGAEVIRMIHTLLGEENFQKGM 425 Query: 462 VQYLQKHSYKNTKNEDLWDSMASICPTDGVKGMDGFCSRSQHSSSSSHWHQEGVDVKTMM 521 Y ++H D A+ C D F + +S+ H Sbjct: 426 QLYFERH-----------DGSAATC--------DDFVQAMEDASNVDLSH---------F 457 Query: 522 NTWTLQKGFPLITI 535 W Q G P++T+ Sbjct: 458 RRWYSQSGTPIVTV 471 >2XPY-A nrPDB Length = 632 Score = 85.1 bits (209), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 86/330 (26%), Positives = 133/330 (40%), Gaps = 33/330 (10%) Query: 168 RTKEGELRILASTQFEPTAARMAFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTV 227 +TK G+ + + Q E AR FPCFD P+ K++F+ I S +P+V S Sbjct: 134 QTKGGKPYVFS--QLEAIHARSLFPCFDTPSVKSTFTASIE--------SPLPVVFSGIR 183 Query: 228 AEGLIED----HFDVTVKMSTYLVAFIISDFESVSKITKSGVKVSVYAVPDKINQADYAL 283 E +D F+ V + YL+ D S G + +VY P ++ + Sbjct: 184 IEDTSKDTNIYRFEQKVPIPAYLIGIASGDLSSAP----IGPRSTVYTEPFRLKDCQWEF 239 Query: 284 DAAVTLLEFYEDYFSIPYPLPKQD-LAAIPDFQSGAMENWGLTTYRESALLFDAEKSSAS 342 + V + Y D L + + G ME+ +T + + D Sbjct: 240 ENDVEKFIQTAEKIIFEYEWGTYDILVNVDSYPYGGMESPNMTFATPTLIAHD------R 293 Query: 343 SKLGITMTVAHELAHQWFGNLVTMEWWNDLWLNEGFAKFMEFVSVSVTHPE-LKVGDYFF 401 S + + +AHELAH W GNLVT WN WLNEG+ ++E + H E + Sbjct: 294 SNIDV---IAHELAHSWSGNLVTNCSWNHFWLNEGWTVYLERRIIGAIHGEPTRHFSALI 350 Query: 402 GKCFDAMEVDALNSSHPVSTPVEN---PAQIREMFDDVSYDKGACILNMLREYLSADA-F 457 G +D++ ST V+N + F V Y+KG +L L L A F Sbjct: 351 GWSDLQNSIDSMKDPERFSTLVQNLNDNTDPDDAFSTVPYEKGFNLLFHLETILGGKAEF 410 Query: 458 KSGIVQYLQKHSYKNTKNEDLWDSMASICP 487 I Y +K + K+ D++ P Sbjct: 411 DPFIRHYFKKFAKKSLDTFQFLDTLYEFYP 440 >3CIA-A nrPDB Length = 605 Score = 81.3 bits (199), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 75/301 (24%), Positives = 129/301 (42%), Gaps = 31/301 (10%) Query: 180 TQFEPTAARMAFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGLIED---HF 236 +Q + AR P D P+ + +++ +I + LA V S G D F Sbjct: 143 SQNQAIHARSWIPIQDTPSVRVTYTARITTDKDLLA------VMSANNEPGTERDGDYFF 196 Query: 237 DVTVKMSTYLVAFIISDFESVSKITKSGVKVSVYAVPDKINQADYALDAAVTLLEFYEDY 296 + + YL+A + D E + ++G+ Y + + + D +++ E Sbjct: 197 SMPQAIPPYLIAIGVGDLEFKAMSHQTGIYAESYILDAAVAE----FDDTQAMIDKAEQM 252 Query: 297 FSIPYPLPKQDLAAIP-DFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVAHEL 355 + Y + DL +P F G MEN L+ + + D + +AHEL Sbjct: 253 YG-KYRWGRYDLLMLPPSFPFGGMENPRLSFITPTVVAGDK---------SLVNLIAHEL 302 Query: 356 AHQWFGNLVTMEWWNDLWLNEGFAKFME-FVSVSVTHPELKVGDYFFGK---CFDAMEVD 411 AH W GNLVT E W DLWLNEGF ++E + +V + V + G + +E+D Sbjct: 303 AHSWSGNLVTNESWRDLWLNEGFTSYVENRIMEAVFGTDRAVMEQALGAQDLNAEILELD 362 Query: 412 ALNSSHPVSTPVENPAQIREMFDDVSYDKGACILNMLREYLSADAFKSGIVQYLQKHSYK 471 A ++ + +P + F V Y KG L L E + F + +++Y H+++ Sbjct: 363 ASDTQLYIDLKGRDP---DDAFSGVPYVKGQLFLMYLEEKFGRERFDAFVLEYFDSHAFQ 419 Query: 472 N 472 + Sbjct: 420 S 420 >5ZI5-A nrPDB Length = 921 Score = 71.6 bits (174), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 87/389 (22%), Positives = 159/389 (40%), Gaps = 32/389 (8%) Query: 112 GERLSEEPLQVLEHPRQEQIALLAPEPLLV-----GLPYTVVIHYAGNLSETFHGFYKST 166 GE ++ LQ+ ++ +E L + L++ P+T+ + + G Y++ Sbjct: 88 GENMTLVSLQMNDNLLKENEYELTKDSLIIKNIPQNTPFTIEMTSLLGENTDLFGLYET- 146 Query: 167 YRTKEGELRILASTQFEPTAARMAFPCFDEPAFKASFSIKI--RREPRHLAISNMPLVKS 224 EG +A + E R F D P A++ I +E + +SN L++ Sbjct: 147 ----EG----VALVKAESEGLRRVFYLPDRPDNLATYKTTIIANQEDYPVLLSNGVLIEK 198 Query: 225 VTVAEGLIEDHFDVTVKMSTYLVAFIISDFE-SVSKI-TKSG--VKVSVYAVPDKINQAD 280 + GL + V +YL A + + + SV+ TKSG + + Y P ++ D Sbjct: 199 KELPLGLHSVTWLDDVPKPSYLFALVAGNLQRSVTYYQTKSGRELPIEFYVPPSATSKCD 258 Query: 281 YALDAAVTLLEFYEDYFSIPYPLPKQDLAAIPDFQSGAMENWGLTTYRESALLFDAEKSS 340 +A + + + E F++ L + +A + + SGA E GL + L E + Sbjct: 259 FAKEVLKEAMAWDERTFNLECALRQHMVAGVDKYASGASEPTGLNLFNTENLFASPETKT 318 Query: 341 ASSKLGITMTVAHELAHQWFGNLVTMEWWNDLWLNEGFAKFMEFVSVSVTHPELKVGDYF 400 L + VAHE H W G+ VT+ W +L L EG F ++ EL D Sbjct: 319 DLGILRVLEVVAHEFFHYWSGDRVTIRDWFNLPLKEGLTTF----RAAMFREELFGTDLI 374 Query: 401 FGKCFDAMEVDALNSSHPVSTPVENPAQIREMFDDVSYDKGACILNMLREYLSADAFKSG 460 + D +D T V R ++ +Y+K A I M+ ++ + F Sbjct: 375 --RLLDGKNLDERAPRQSAYTAV------RSLYTAAAYEKSADIFRMMMLFIGKEPFIEA 426 Query: 461 IVQYLQKHSYKNTKNEDLWDSMASICPTD 489 + ++ + + ED +S+++ D Sbjct: 427 VAKFFKDNDGGAVTLEDFIESISNSSGKD 455 >4OON-A nrPDB Length = 795 Score = 32.0 bits (71), Expect = 1.2, Method: Compositional matrix adjust. Identities = 22/90 (24%), Positives = 44/90 (48%), Gaps = 12/90 (13%) Query: 394 LKVGDYFFGKCFDAMEVDALNSSHPVSTPVENPAQIREM--------FDDVSYDKGACIL 445 LK+G + + + A + +N+S+ V TP N I EM + +Y +G ++ Sbjct: 203 LKLG-FIDQQRYQAAVEEPINASYHVQTPELNAPYIAEMARAEMVGRYGSEAYTEGYKVI 261 Query: 446 NMLREYL---SADAFKSGIVQYLQKHSYKN 472 +R L ++ + + G++ Y Q+H Y+ Sbjct: 262 TTVRSDLQNAASQSVRDGLIDYDQRHGYRG 291 >6C57-A nrPDB Length = 322 Score = 30.4 bits (67), Expect = 3.9, Method: Compositional matrix adjust. Identities = 19/64 (29%), Positives = 33/64 (51%), Gaps = 7/64 (10%) Query: 233 EDHFDVTVKMSTYL--VAFIISDFESVSKITKS-GVKVSVYAVPDKINQADY----ALDA 285 ED + ++++ L + +I D E SK+ + V S+Y +P IN A+Y L+ Sbjct: 65 EDKLQIIIEVTEMLHNASLLIDDIEDNSKLRRGFPVAHSIYGIPSVINSANYVYFLGLEK 124 Query: 286 AVTL 289 +TL Sbjct: 125 VLTL 128 >5GUJ-A nrPDB Length = 324 Score = 30.4 bits (67), Expect = 4.1, Method: Compositional matrix adjust. Identities = 29/110 (26%), Positives = 46/110 (41%), Gaps = 21/110 (19%) Query: 225 VTVAEGLIEDHFDVTVKMSTYLVAFIISD---FESVSK----ITKSGVKVSVYAVPDKIN 277 T+ L +DH + + ++ SD +E+ K + K G KV V +PD ++ Sbjct: 175 ATMGTSLTDDHVKILRRNVEEIILCYDSDKAGYEATLKASELLQKKGCKVRVAMIPDGLD 234 Query: 278 QADY------------ALDAAVTLLEFYEDYFSIPYPLPKQD--LAAIPD 313 DY +DA+VT++ F YF L + LA I D Sbjct: 235 PDDYIKKFGGEKFKNDIIDASVTVMAFKMQYFRKGKNLSDEGDRLAYIKD 284 >4NT4-A nrPDB Length = 312 Score = 30.4 bits (67), Expect = 4.2, Method: Compositional matrix adjust. Identities = 14/31 (45%), Positives = 20/31 (64%) Query: 690 RDMNEVETQFKAFLIRLLRDLIDKQTWTDEG 720 R ++ ET FL RL +DL D++ +TDEG Sbjct: 269 RRLDFFETPDYDFLRRLFQDLFDRKGYTDEG 299 >1AKO-A nrPDB Length = 268 Score = 29.6 bits (65), Expect = 6.3, Method: Compositional matrix adjust. Identities = 28/106 (26%), Positives = 43/106 (40%), Gaps = 13/106 (12%) Query: 126 PRQEQIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRILASTQFEPT 185 P Q + + +P ++GL T V L E Y Y ++G + T+ P Sbjct: 15 PHQLEAIVEKHQPDVIGLQETKVHDDMFPLEEVAKLGYNVFYHGQKGHYGVALLTKETPI 74 Query: 186 AARMAFPCFDEPAFKASFSIKIRREPRHLAISNMP-LVKSVTVAEG 230 A R FP DE A R + ++ +P L+ +VTV G Sbjct: 75 AVRRGFPGDDEEA------------QRRIIMAEIPSLLGNVTVING 108 >3CH8-A nrPDB Length = 195 Score = 29.6 bits (65), Expect = 7.3, Method: Composition-based stats. Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 11/94 (11%) Query: 80 TKVEITASQPTSTIILHSHHLQISRATLRKGAGERLSEEPLQVLEHPRQEQIALLAPEPL 139 T +E+ A+ PTS +I + ++ + R GE P+Q P + A ++ L Sbjct: 109 TNLEVVAATPTSLLISWDAYRELPVSYYRITYGETGGNSPVQEFTVPGSKSTATIS--GL 166 Query: 140 LVGLPYTVVIHYAGNLSETFHGFYKS----TYRT 169 G+ YT+ ++ N +H +Y S YRT Sbjct: 167 KPGVDYTITVYAHYN----YH-YYSSPISINYRT 195 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3QNF-A nrPDB 1305 0.0 3SE6-A nrPDB 1175 0.0 5C97-A nrPDB 1069 0.0 5LHD-A nrPDB 1022 0.0 5LG6-A nrPDB 1017 0.0 4KXA-A nrPDB 978 0.0 4WZ9-A nrPDB 787 0.0 1Z1W-A nrPDB 579 e-165 3RJO-A nrPDB 571 e-163 5DLL-A nrPDB 423 e-118 4Q4I-A nrPDB 391 e-109 4QHP-A nrPDB 390 e-108 5Y1X-A nrPDB 362 e-100 5FWQ-A nrPDB 346 3e-95 5ZI5-A nrPDB 345 6e-95 4GAA-A nrPDB 329 5e-90 2XPY-A nrPDB 311 1e-84 3CIA-A nrPDB 292 4e-79 Sequences not found previously or not previously below threshold: 3ZUK-A nrPDB 36 0.073 4XBH-A nrPDB 35 0.13 3MDV-A nrPDB 35 0.17 2C4R-L nrPDB 35 0.18 4CTH-A nrPDB 34 0.26 4FGM-A nrPDB 34 0.29 2G9B-A nrPDB 33 0.55 6NF9-A nrPDB 33 0.63 4ARF-A nrPDB 32 0.79 1BQB-A nrPDB 32 0.86 1XMD-A nrPDB 32 1.1 4B52-A nrPDB 31 2.0 3CQB-A nrPDB 31 2.7 5TON-A nrPDB 30 5.2 5IMY-A nrPDB 30 6.4 1W8I-A nrPDB 29 9.1 CONVERGED! >3QNF-A nrPDB Length = 954 Score = 1305 bits (3377), Expect = 0.0, Method: Composition-based stats. Identities = 941/941 (100%), Positives = 941/941 (100%) Query: 1 MVFLPLKWSLATMSFLLSSLLALLTVSTPSWCQSTEASPKRSDGTPFPWNKIRLPEYVIP 60 MVFLPLKWSLATMSFLLSSLLALLTVSTPSWCQSTEASPKRSDGTPFPWNKIRLPEYVIP Sbjct: 7 MVFLPLKWSLATMSFLLSSLLALLTVSTPSWCQSTEASPKRSDGTPFPWNKIRLPEYVIP 66 Query: 61 VHYDLLIHANLTTLTFWGTTKVEITASQPTSTIILHSHHLQISRATLRKGAGERLSEEPL 120 VHYDLLIHANLTTLTFWGTTKVEITASQPTSTIILHSHHLQISRATLRKGAGERLSEEPL Sbjct: 67 VHYDLLIHANLTTLTFWGTTKVEITASQPTSTIILHSHHLQISRATLRKGAGERLSEEPL 126 Query: 121 QVLEHPRQEQIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRILAST 180 QVLEHPRQEQIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRILAST Sbjct: 127 QVLEHPRQEQIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRILAST 186 Query: 181 QFEPTAARMAFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGLIEDHFDVTV 240 QFEPTAARMAFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGLIEDHFDVTV Sbjct: 187 QFEPTAARMAFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGLIEDHFDVTV 246 Query: 241 KMSTYLVAFIISDFESVSKITKSGVKVSVYAVPDKINQADYALDAAVTLLEFYEDYFSIP 300 KMSTYLVAFIISDFESVSKITKSGVKVSVYAVPDKINQADYALDAAVTLLEFYEDYFSIP Sbjct: 247 KMSTYLVAFIISDFESVSKITKSGVKVSVYAVPDKINQADYALDAAVTLLEFYEDYFSIP 306 Query: 301 YPLPKQDLAAIPDFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVAHELAHQWF 360 YPLPKQDLAAIPDFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVAHELAHQWF Sbjct: 307 YPLPKQDLAAIPDFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVAHELAHQWF 366 Query: 361 GNLVTMEWWNDLWLNEGFAKFMEFVSVSVTHPELKVGDYFFGKCFDAMEVDALNSSHPVS 420 GNLVTMEWWNDLWLNEGFAKFMEFVSVSVTHPELKVGDYFFGKCFDAMEVDALNSSHPVS Sbjct: 367 GNLVTMEWWNDLWLNEGFAKFMEFVSVSVTHPELKVGDYFFGKCFDAMEVDALNSSHPVS 426 Query: 421 TPVENPAQIREMFDDVSYDKGACILNMLREYLSADAFKSGIVQYLQKHSYKNTKNEDLWD 480 TPVENPAQIREMFDDVSYDKGACILNMLREYLSADAFKSGIVQYLQKHSYKNTKNEDLWD Sbjct: 427 TPVENPAQIREMFDDVSYDKGACILNMLREYLSADAFKSGIVQYLQKHSYKNTKNEDLWD 486 Query: 481 SMASICPTDGVKGMDGFCSRSQHSSSSSHWHQEGVDVKTMMNTWTLQKGFPLITITVRGR 540 SMASICPTDGVKGMDGFCSRSQHSSSSSHWHQEGVDVKTMMNTWTLQKGFPLITITVRGR Sbjct: 487 SMASICPTDGVKGMDGFCSRSQHSSSSSHWHQEGVDVKTMMNTWTLQKGFPLITITVRGR 546 Query: 541 NVHMKQEHYMKGSDGAPDTGYLWHVPLTFITSKSDMVHRFLLKTKTDVLILPEEVEWIKF 600 NVHMKQEHYMKGSDGAPDTGYLWHVPLTFITSKSDMVHRFLLKTKTDVLILPEEVEWIKF Sbjct: 547 NVHMKQEHYMKGSDGAPDTGYLWHVPLTFITSKSDMVHRFLLKTKTDVLILPEEVEWIKF 606 Query: 601 NVGMNGYYIVHYEDDGWDSLTGLLKGTHTAVSSNDRASLINNAFQLVSIGKLSIEKALDL 660 NVGMNGYYIVHYEDDGWDSLTGLLKGTHTAVSSNDRASLINNAFQLVSIGKLSIEKALDL Sbjct: 607 NVGMNGYYIVHYEDDGWDSLTGLLKGTHTAVSSNDRASLINNAFQLVSIGKLSIEKALDL 666 Query: 661 SLYLKHETEIMPVFQGLNELIPMYKLMEKRDMNEVETQFKAFLIRLLRDLIDKQTWTDEG 720 SLYLKHETEIMPVFQGLNELIPMYKLMEKRDMNEVETQFKAFLIRLLRDLIDKQTWTDEG Sbjct: 667 SLYLKHETEIMPVFQGLNELIPMYKLMEKRDMNEVETQFKAFLIRLLRDLIDKQTWTDEG 726 Query: 721 SVSERMLRSQLLLLACVHNYQPCVQRAEGYFRKWKESNGNLSLPVDVTLAVFAVGAQSTE 780 SVSERMLRSQLLLLACVHNYQPCVQRAEGYFRKWKESNGNLSLPVDVTLAVFAVGAQSTE Sbjct: 727 SVSERMLRSQLLLLACVHNYQPCVQRAEGYFRKWKESNGNLSLPVDVTLAVFAVGAQSTE 786 Query: 781 GWDFLYSKYQFSLSSTEKSQIEFALCRTQNKEKLQWLLDESFKGDKIKTQEFPQILTLIG 840 GWDFLYSKYQFSLSSTEKSQIEFALCRTQNKEKLQWLLDESFKGDKIKTQEFPQILTLIG Sbjct: 787 GWDFLYSKYQFSLSSTEKSQIEFALCRTQNKEKLQWLLDESFKGDKIKTQEFPQILTLIG 846 Query: 841 RNPVGYPLAWQFLRKNWNKLVQKFELGSSSIAHMVMGTTNQFSTRTRLEEVKGFFSSLKE 900 RNPVGYPLAWQFLRKNWNKLVQKFELGSSSIAHMVMGTTNQFSTRTRLEEVKGFFSSLKE Sbjct: 847 RNPVGYPLAWQFLRKNWNKLVQKFELGSSSIAHMVMGTTNQFSTRTRLEEVKGFFSSLKE 906 Query: 901 NGSQLRCVQQTIETIEENIGWMDKNFDKIRVWLQSEKLERM 941 NGSQLRCVQQTIETIEENIGWMDKNFDKIRVWLQSEKLERM Sbjct: 907 NGSQLRCVQQTIETIEENIGWMDKNFDKIRVWLQSEKLERM 947 >3SE6-A nrPDB Length = 967 Score = 1175 bits (3039), Expect = 0.0, Method: Composition-based stats. Identities = 474/934 (50%), Positives = 644/934 (68%), Gaps = 15/934 (1%) Query: 15 FLLSSLLALLTV----STPSWCQSTE---ASPKRSDGTPFPWNKIRLPEYVIPVHYDLLI 67 + L+++L + + S PS TE A P ++G FPW ++RLP VIP+HYDL + Sbjct: 23 YCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFV 82 Query: 68 HANLTTLTFWGTTKVEITASQPTSTIILHSHHLQISRATLRKGAGERLSE--EPLQVLEH 125 H NLT+L F + K+E+ S T IILHS L+I+ ATL+ R + + L+VL + Sbjct: 83 HPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSY 142 Query: 126 PRQEQIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRILASTQFEPT 185 P EQIALL PE L L Y V + + L + F GFYKSTYRT GE RILA T FEPT Sbjct: 143 PAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPT 202 Query: 186 AARMAFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGLIEDHFDVTVKMSTY 245 ARMAFPCFDEP FKA+FSIKIRRE RH+A+SNMP VK++ + GL+EDHF+ TVKMSTY Sbjct: 203 QARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTY 262 Query: 246 LVAFIISDFESVSKITKSGVKVSVYAVPDKINQADYALDAAVTLLEFYEDYFSIPYPLPK 305 LVA+I+ DF S+S T SGVKVS+YA PDK NQ YAL A++ LL+FYE YF I YPL K Sbjct: 263 LVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSK 322 Query: 306 QDLAAIPDFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVAHELAHQWFGNLVT 365 DL AIPDF GAMENWGL TYRE++LLFD + SSAS KL +T +AHELAHQWFGNLVT Sbjct: 323 LDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVT 382 Query: 366 MEWWNDLWLNEGFAKFMEFVSVSVTHPELKVGDYFFGKCFDAMEVDALNSSHPVSTPVEN 425 MEWWND+WLNEGFAK+ME ++V+ T+PEL+ DYF CF+ + D+LNSS P+S P E Sbjct: 383 MEWWNDIWLNEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAET 442 Query: 426 PAQIREMFDDVSYDKGACILNMLREYLSADAFKSGIVQYLQKHSYKNTKNEDLWDSMASI 485 P QI+EMFD+VSY+KGACILNML+++L + F+ GI+QYL+K SY+N KN+DLW S+++ Sbjct: 443 PTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNS 502 Query: 486 CPTDGVKGMDGFCSRSQHSSSSSHWHQEGVDVKTMMNTWTLQKGFPLITITVRGRNVHMK 545 C S + +S+ + E +VK MM TWTLQKG PL+ + G ++ ++ Sbjct: 503 CLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQ 562 Query: 546 QEHYMK------GSDGAPDTGYLWHVPLTFITSKSDMVHRFLLKTKTDVLILPEEVEWIK 599 QE +++ A YLWH+PLT+ TS S+++HR +LK+KTD L LPE+ W+K Sbjct: 563 QERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVK 622 Query: 600 FNVGMNGYYIVHYEDDGWDSLTGLLKGTHTAVSSNDRASLINNAFQLVSIGKLSIEKALD 659 FNV NGYYIVHYE GWD L L HT + DR LI++ FQLV G+L+++KALD Sbjct: 623 FNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALD 682 Query: 660 LSLYLKHETEIMPVFQGLNELIPMYKLMEKRDMNEVETQFKAFLIRLLRDLIDKQTWTDE 719 ++ YL+HET + +GL+ L Y +M++R+++++ K +L++ + +ID+Q+W+D+ Sbjct: 683 MTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDK 742 Query: 720 GSVSERMLRSQLLLLACVHNYQPCVQRAEGYFRKWKESNGNLSLPVDVTLAVFAVGAQST 779 GSV +RMLRS LL LAC N+ PC+Q+A F +W ES+G L++P DV V++VGAQ+T Sbjct: 743 GSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTT 802 Query: 780 EGWDFLYSKYQFSLSSTEKSQIEFALCRTQNKEKLQWLLDESFKGDKIKTQEFPQILTLI 839 GW++L +Y+ S+SS E+++I +AL ++++EKL L++ +G IKTQ +L I Sbjct: 803 AGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAI 862 Query: 840 GRNPVGYPLAWQFLRKNWNKLVQKFELGSSSIAHMVMGTTNQFSTRTRLEEVKGFFSSLK 899 R P G LAW F+R+NW L++KF+LGS I ++ GTT FS++ +L+EVK FF SL+ Sbjct: 863 ARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLE 922 Query: 900 ENGSQLRCVQQTIETIEENIGWMDKNFDKIRVWL 933 GS L Q +ETI +NI W++KN +R WL Sbjct: 923 AQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWL 956 >5C97-A nrPDB Length = 912 Score = 1069 bits (2765), Expect = 0.0, Method: Composition-based stats. Identities = 416/906 (45%), Positives = 576/906 (63%), Gaps = 34/906 (3%) Query: 37 ASPKRSDGTPFPWNKIRLPEYVIPVHYDLLIHANLTTLTFWGTTKVEITASQPTSTIILH 96 A ++G FPW +IRLP V+P+ Y+L +H NLT++TF G+ + + A Q T IILH Sbjct: 28 AETGATNGKLFPWAQIRLPTAVVPLRYELSLHPNLTSMTFRGSVTISVQALQVTWNIILH 87 Query: 97 SHHLQISRATLRKGAGERLSEEPLQVLEHPRQEQIALLAPEPLLVGLPYTVVIHYAGNLS 156 S ISR T + E+ ++LE+ QIA++APE LL G YT+ I Y+ N+S Sbjct: 88 STGHNISRVTFMSAVSSQ--EKQAEILEYAYHGQIAIVAPEALLAGHNYTLKIEYSANIS 145 Query: 157 ETFHGFYKSTYRTKEGELRILASTQFEPTAARMAFPCFDEPAFKASFSIKIRREPRHLAI 216 +++GFY +Y + E + A+TQFEP AAR AFPCFDEPAFKA+F IKI R+ ++ A+ Sbjct: 146 SSYYGFYGFSYTDESNEKKYFAATQFEPLAARSAFPCFDEPAFKATFIIKIIRDEQYTAL 205 Query: 217 SNMPLVKSVTVAEGLIEDHFDVTVKMSTYLVAFIISDFESVSKITKSGVKVSVYAVPDKI 276 SNMP SV + +GL++D F +VKMSTYLVAFI+ + +++S+ +G VS+YAVP+KI Sbjct: 206 SNMPKKSSVVLDDGLVQDEFSESVKMSTYLVAFIVGEMKNLSQDV-NGTLVSIYAVPEKI 264 Query: 277 NQADYALDAAVTLLEFYEDYFSIPYPLPKQDLAAIPDFQSGAMENWGLTTYRESALLFDA 336 Q YAL+ V LLEF+++YF I YPL K DL AIPDF++GAMENWGL T+RE LL+D+ Sbjct: 265 GQVHYALETTVKLLEFFQNYFEIQYPLKKLDLVAIPDFEAGAMENWGLLTFREETLLYDS 324 Query: 337 EKSSASSKLGITMTVAHELAHQWFGNLVTMEWWNDLWLNEGFAKFMEFVSVSVTHPELKV 396 SS + + +T +AHELAHQWFGNLVTM+WWNDLWLNEGFA FME+ S+ EL Sbjct: 325 NTSSMADRKLVTKIIAHELAHQWFGNLVTMKWWNDLWLNEGFATFMEYFSLEKIFKELSS 384 Query: 397 GDYFFGKCFDAMEVDALNSSHPVSTPVENPAQIREMFDDVSYDKGACILNMLREYLSADA 456 + F F M+ D+LNSSHP+S+ V++ QI EMFD +SY KG+ +L ML+ YLS D Sbjct: 385 YEDFLDARFKTMKKDSLNSSHPISSSVQSSEQIEEMFDSLSYFKGSSLLLMLKTYLSEDV 444 Query: 457 FKSGIVQYLQKHSYKNTKNEDLWDSMASICPTDGVKGMDGFCSRSQHSSSSSHWHQEGVD 516 F+ +V YL HSY + +++DLWDS + + +D Sbjct: 445 FQHAVVLYLHNHSYASIQSDDLWDSFNEVTN-------------------------QTLD 479 Query: 517 VKTMMNTWTLQKGFPLITITVRGRNVHMKQEHY---MKGSDGAPDTGYLWHVPLTFITSK 573 VK MM TWTLQKGFPL+T+ +G+ + ++QE + MK DT YLWH+PL+++T Sbjct: 480 VKRMMKTWTLQKGFPLVTVQKKGKELFIQQERFFLNMKPEIQPSDTSYLWHIPLSYVTEG 539 Query: 574 SDMVHRF---LLKTKTDVLILPEEVEWIKFNVGMNGYYIVHYEDDGWDSLTGLLKGTHTA 630 + LL K+ V+ L EEV W+K N+ MNGYYIVHY DD W++L LK Sbjct: 540 RNYSKYQSVSLLDKKSGVINLTEEVLWVKVNINMNGYYIVHYADDDWEALIHQLKINPYV 599 Query: 631 VSSNDRASLINNAFQLVSIGKLSIEKALDLSLYLKHETEIMPVFQGLNELIPMYKLMEKR 690 +S DRA+LINN F+L +GK+ +++A DL YL +E P+ + L + +Y L+EK Sbjct: 600 LSDKDRANLINNIFELAGLGKVPLKRAFDLINYLGNENHTAPITEALFQTDLIYNLLEKL 659 Query: 691 DMNEVETQFKAFLIRLLRDLIDKQTWTDEGSVSERMLRSQLLLLACVHNYQPCVQRAEGY 750 ++ ++ + +LL++ I +QTWTDEG+ S R LRS LL AC HN C A Sbjct: 660 GYMDLASRLVTRVFKLLQNQIQQQTWTDEGTPSMRELRSALLEFACTHNLGNCSTTAMKL 719 Query: 751 FRKWKESNGNLSLPVDVTLAVFAVGAQSTEGWDFLYSKYQFSLSSTEKSQIEFALCRTQN 810 F W SNG SLP DV VF VGA++ +GW FL KY S EK++I AL +++ Sbjct: 720 FDDWMASNGTQSLPTDVMTTVFKVGAKTDKGWSFLLGKYISIGSEAEKNKILEALASSED 779 Query: 811 KEKLQWLLDESFKGDKIKTQEFPQILTLIGRNPVGYPLAWQFLRKNWNKLVQKFELGSSS 870 KL WL+ S GD +TQ+ I+ +GR+ G+ LAW F+++NWNKLVQKF LGS + Sbjct: 780 VRKLYWLMKSSLNGDNFRTQKLSFIIRTVGRHFPGHLLAWDFVKENWNKLVQKFPLGSYT 839 Query: 871 IAHMVMGTTNQFSTRTRLEEVKGFFSSLKENGSQLRCVQQTIETIEENIGWMDKNFDKIR 930 I ++V G+T FST+T L EV+ FF + E +LRCVQ+ +E I+ NI WM+KN + Sbjct: 840 IQNIVAGSTYLFSTKTHLSEVQAFFENQSEATFRLRCVQEALEVIQLNIQWMEKNLKSLT 899 Query: 931 VWLQSE 936 WL++E Sbjct: 900 WWLRTE 905 >5LHD-A nrPDB Length = 950 Score = 1022 bits (2641), Expect = 0.0, Method: Composition-based stats. Identities = 306/941 (32%), Positives = 472/941 (50%), Gaps = 61/941 (6%) Query: 27 STPSWCQSTEASPKRSDGTPFPWNKIRLPEYVIPVHYDLLIHANLTT-----LTFWGTTK 81 +TPS +T + + WN+ RLP + P Y + + LT F G++ Sbjct: 32 TTPSASATTNPASATTLDQSKAWNRYRLPNTLKPDSYRVTLRPYLTPNDRGLYVFKGSST 91 Query: 82 VEITASQPTSTIILHSHHLQIS-----RATLRKGAGERLSEEPLQVLEHPRQEQIALLAP 136 V T + T II+HS L + R LR G + + L P + + L Sbjct: 92 VRFTCKEATDVIIIHSKKLNYTLSQGHRVVLRGVGGSQPPDIDKTELVEPTEYLVVHLKG 151 Query: 137 EPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRILASTQFEPTAARMAFPCFDE 196 L+ Y + + G L++ GFY+S Y + +++A+TQ + AR +FPCFDE Sbjct: 152 -SLVKDSQYEMDSEFEGELADDLAGFYRSEYM-EGNVRKVVATTQMQAADARKSFPCFDE 209 Query: 197 PAFKASFSIKIRREPRHLAISNM-PLVKSVTVAEG--LIEDHFDVTVKMSTYLVAFIISD 253 PA KA F+I + A+SNM P S + E F T KMSTYL+AFI+S+ Sbjct: 210 PAMKAEFNITLIHPKDLTALSNMLPKGPSTPLPEDPNWNVTEFHTTPKMSTYLLAFIVSE 269 Query: 254 FESVSKITKSGVKVSVYAVPDKI--NQADYALDAAVTLLEFYEDYFSIPYPLPKQDLAAI 311 F+ V K +GV + ++A P I DYAL+ +L F+ ++ PYPLPK D + Sbjct: 270 FDYVEKQASNGVLIRIWARPSAIAAGHGDYALNVTGPILNFFAGHYDTPYPLPKSDQIGL 329 Query: 312 PDFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVAHELAHQWFGNLVTMEWWND 371 PDF +GAMENWGL TYRE++LLFD SS+S+K + +AHELAHQWFGNLVT+EWWND Sbjct: 330 PDFNAGAMENWGLVTYRENSLLFDPLSSSSSNKERVVTVIAHELAHQWFGNLVTIEWWND 389 Query: 372 LWLNEGFAKFMEFVSVSVTHPELKVGDYF-FGKCFDAMEVDALNSSHPVSTP---VENPA 427 LWLNEGFA ++E++ P + D + M VDAL SSHP+STP + PA Sbjct: 390 LWLNEGFASYVEYLGADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSTPASEINTPA 449 Query: 428 QIREMFDDVSYDKGACILNMLREYLSADAFKSGIVQYLQKHSYKNTKNEDLWDSMASICP 487 QI E+FD +SY KGA +L ML +LS D FK G+ YL +Y+NT +LWD + Sbjct: 450 QISELFDAISYSKGASVLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYLNLWDHLQEAVN 509 Query: 488 TDGVKGMDGFCSRSQHSSSSSHWHQEGVDVKTMMNTWTLQKGFPLITITVRGRNVHMKQE 547 + Q V+ +MN WTLQ GFP+IT+ + QE Sbjct: 510 NRSI--------------------QLPTTVRDIMNRWTLQMGFPVITVDTSTG--TLSQE 547 Query: 548 HYMKGSDG----APDTGYLWHVPLTFITSKSDMVHRFLLKTKT-DVLILPEEVEWIKFNV 602 H++ D + Y+W VP+T I +L+ + + L EW+ N+ Sbjct: 548 HFLLDPDSNVTRPSEFNYVWIVPITSIRDGRQQQDYWLIDVRAQNDLFSTSGNEWVLLNL 607 Query: 603 GMNGYYIVHYEDDGWDSLTGLLKGTHTAVSSNDRASLINNAFQLVSIGKLSIEKALDLSL 662 + GYY V+Y+++ W + L+ H+A+ +RA +IN+AF L S K+ + AL+ +L Sbjct: 608 NVTGYYRVNYDEENWRKIQTQLQRDHSAIPVINRAQIINDAFNLASAHKVPVTLALNNTL 667 Query: 663 YLKHETEIMPVFQGLNELIPMYKLMEKRDMNEVETQFKAFLIRLLRDLI-----DKQTWT 717 +L E + MP L+ L +KLM R +EV K +L + + L + W Sbjct: 668 FLIEERQYMPWEAALSSL-SYFKLMFDR--SEVYGPMKNYLKKQVTPLFIHFRNNTNNWR 724 Query: 718 D-EGSVSERMLRSQLLLLACVHNYQPCVQRAEGYFRKWKESNGNLSLPVDVTLAVFA--V 774 + ++ ++ + AC + C + G F++W E+ N + ++ V+ + Sbjct: 725 EIPENLMDQYSEVNAISTACSNGVPECEEMVSGLFKQWMENPNNNPIHPNLRSTVYCNAI 784 Query: 775 GAQSTEGWDFLYSKYQFSLSSTEKSQIEFALCRTQNKEKLQWLLDESFKGDKIKTQEFPQ 834 E WDF + +++ + E ++ AL ++ L L + D I+ Q+ Sbjct: 785 AQGGEEEWDFAWEQFRNATLVNEADKLRAALACSKELWILNRYLSYTLNPDLIRKQDATS 844 Query: 835 ILTLIGRNPVGYPLAWQFLRKNWNKLVQKFELGSSSIAHMVMGTTNQFSTRTRLEEVKGF 894 + I N +G L W F++ NW KL + GS S ++++ T +FST L++++ F Sbjct: 845 TIISITNNVIGQGLVWDFVQSNWKKLFNDYGGGSFSFSNLIQAVTRRFSTEYELQQLEQF 904 Query: 895 FSSLKEN--GSQLRCVQQTIETIEENIGWMDKNFDKIRVWL 933 +E GS R ++Q +E + NI W+ +N + + W Sbjct: 905 KKDNEETGFGSGTRALEQALEKTKANIKWVKENKEVVLQWF 945 >5LG6-A nrPDB Length = 968 Score = 1017 bits (2629), Expect = 0.0, Method: Composition-based stats. Identities = 299/925 (32%), Positives = 474/925 (51%), Gaps = 60/925 (6%) Query: 43 DGTPFPWNKIRLPEYVIPVHYDLLIHANLTT-----LTFWGTTKVEITASQPTSTIILHS 97 PWN+ RLP ++P Y++ + LT F G + V +PT II+HS Sbjct: 43 LDQSKPWNRYRLPTTLLPDSYNVTLRPYLTPNADGLYIFKGKSIVRFICQEPTDVIIIHS 102 Query: 98 HHLQIS---RATLRKGAGE-RLSEEPLQVLEHPRQEQIALLAPEPLLVGLPYTVVIHYAG 153 L + + +G G+ ++ E L + + L L G Y + + G Sbjct: 103 KKLNYTTQGHMVVLRGVGDSQVPEIDRTELVELTEYLVVHLKG-SLQPGHMYEMESEFQG 161 Query: 154 NLSETFHGFYKSTYRTKEGELRILASTQFEPTAARMAFPCFDEPAFKASFSIKIRREPRH 213 L++ GFY+S Y + ++LA+TQ + T AR +FPCFDEPA KA+F+I + Sbjct: 162 ELADDLAGFYRSEYM-EGNVKKVLATTQMQSTDARKSFPCFDEPAMKATFNITLIHPNNL 220 Query: 214 LAISNMPLVKSVT---VAEGLIEDHFDVTVKMSTYLVAFIISDFESVSKITKSGVKVSVY 270 A+SNMP S T F+ T MSTYL+A+I+S+F+SV++ ++GV + ++ Sbjct: 221 TALSNMPPKGSSTPLAEDPNWSVTEFETTPVMSTYLLAYIVSEFQSVNETAQNGVLIRIW 280 Query: 271 AVPDKINQAD--YALDAAVTLLEFYEDYFSIPYPLPKQDLAAIPDFQSGAMENWGLTTYR 328 A P+ I + YAL+ +L F+ ++++ YPLPK D A+PDF +GAMENWGL TYR Sbjct: 281 ARPNAIAEGHGMYALNVTGPILNFFANHYNTSYPLPKSDQIALPDFNAGAMENWGLVTYR 340 Query: 329 ESALLFDAEKSSASSKLGITMTVAHELAHQWFGNLVTMEWWNDLWLNEGFAKFMEFVSVS 388 E+ALLFD + SS S+K + +AHELAHQWFGNLVT+ WWNDLWLNEGFA ++E++ Sbjct: 341 ENALLFDPQSSSISNKERVVTVIAHELAHQWFGNLVTLAWWNDLWLNEGFASYVEYLGAD 400 Query: 389 VTHPELKVGDYFF-GKCFDAMEVDALNSSHPVSTP---VENPAQIREMFDDVSYDKGACI 444 P + D G + M VDAL SSHP++TP V PAQI EMFD +SY KGA + Sbjct: 401 HAEPTWNLKDLIVPGDVYRVMAVDALASSHPLTTPAEEVNTPAQISEMFDSISYSKGASV 460 Query: 445 LNMLREYLSADAFKSGIVQYLQKHSYKNTKNEDLWDSMASICPTDGVKGMDGFCSRSQHS 504 + ML +L+ D FK G+ YL +Y+NT DLW+ + K +D S Sbjct: 461 IRMLSNFLTEDLFKEGLASYLHAFAYQNTTYLDLWEHLQ--------KAVDAQTSIRLPD 512 Query: 505 SSSSHWHQEGVDVKTMMNTWTLQKGFPLITITVRGRNVHMKQEHYMKGSDG----APDTG 560 V+ +M+ WTLQ GFP+IT+ + N+ Q+H++ S+ + Sbjct: 513 -----------TVRAIMDRWTLQMGFPVITVDTKTGNI--SQKHFLLDSESNVTRSSAFD 559 Query: 561 YLWHVPLTFITSKSDMVHRFLLK--TKTDVLILPEEVEWIKFNVGMNGYYIVHYEDDGWD 618 YLW VP++ I + H +L + L +W+ NV + GY+ V+Y++D W Sbjct: 560 YLWIVPISSIKNGVMQDHYWLRDVSQAQNDLFKTASDDWVLLNVNVTGYFQVNYDEDNWR 619 Query: 619 SLTGLLKGTHTAVSSNDRASLINNAFQLVSIGKLSIEKALDLSLYLKHETEIMPVFQGLN 678 + L+ + + +RA +I ++F L + + + ALD +L+L E E MP L+ Sbjct: 620 MIQHQLQTNLSVIPVINRAQVIYDSFNLATAHMVPVTLALDNTLFLNGEKEYMPWQAALS 679 Query: 679 ELIPMYKLMEKRDMNEVETQFKAFLIRLLRDLIDK-----QTWTDEG-SVSERMLRSQLL 732 L + LM R +EV K +L + + L + WT+ ++ ++ + Sbjct: 680 SL-SYFSLMFDR--SEVYGPMKKYLRKQVEPLFQHFETLTKNWTERPENLMDQYSEINAI 736 Query: 733 LLACVHNYQPCVQRAEGYFRKWKESNGNLSLPVDVTLAVFA--VGAQSTEGWDFLYSKYQ 790 AC + C A+ F +W N + ++ ++ + + WDF + + Q Sbjct: 737 STACSNGLPQCENLAKTLFDQWMSDPENNPIHPNLRSTIYCNAIAQGGQDQWDFAWGQLQ 796 Query: 791 FSLSSTEKSQIEFALCRTQNKEKLQWLLDESFKGDKIKTQEFPQILTLIGRNPVGYPLAW 850 + E ++ AL + L L + D I+ Q+ + I N +G PLAW Sbjct: 797 QAQLVNEADKLRSALACSNEVWLLNRYLGYTLNPDLIRKQDATSTINSIASNVIGQPLAW 856 Query: 851 QFLRKNWNKLVQKFELGSSSIAHMVMGTTNQFSTRTRLEEVKGFFSSLKEN--GSQLRCV 908 F++ NW KL Q + GS S ++++ G T +FS+ L++++ F + + GS R + Sbjct: 857 DFVQSNWKKLFQDYGGGSFSFSNLIQGVTRRFSSEFELQQLEQFKKNNMDVGFGSGTRAL 916 Query: 909 QQTIETIEENIGWMDKNFDKIRVWL 933 +Q +E + NI W+ +N + + W Sbjct: 917 EQALEKTKANIKWVKENKEVVLNWF 941 >4KXA-A nrPDB Length = 888 Score = 978 bits (2527), Expect = 0.0, Method: Composition-based stats. Identities = 297/910 (32%), Positives = 485/910 (53%), Gaps = 56/910 (6%) Query: 41 RSDGTPFPWNKIRLPEYVIPVHYDLLIHANLTTLTFWGTTKVEITASQPTSTIILHSHHL 100 S+ W RLP++V PVHYDL + L T+ GT + I S PT + LH Sbjct: 5 ASEDESGQWKNFRLPDFVNPVHYDLHVKPLLEEDTYTGTVSISINLSAPTRYLWLHLRET 64 Query: 101 QISR-ATLRKGAGERLSEEPLQVLEHPRQEQIALLAPEPLLVGLP---YTVVIHYAGNLS 156 +I+R L++ +G+++ + + E+ +QE + + A E L Y + + +AG L+ Sbjct: 65 RITRLPELKRPSGDQV--QVRRCFEYKKQEYVVVEAEEELTPSSGDGLYLLTMEFAGWLN 122 Query: 157 ETFHGFYKSTYRTKEGELRILASTQFEPTAARMAFPCFDEPAFKASFSIKIRREPRHLAI 216 + GFY++TY T+ G ++ +A+T EPT AR +FPCFDEP KA+++I I + A+ Sbjct: 123 GSLVGFYRTTY-TENGRVKSIAATDHEPTDARKSFPCFDEPNKKATYTISITHPKEYGAL 181 Query: 217 SNMPLVKSVTVAEGLIEDHFDVTVKMSTYLVAFIISDFESVSKITKSGVKVSVYAVPDKI 276 SNMP+ K +V + F+ +V MSTYLV F + F+SV +I+ SG +++Y P++ Sbjct: 182 SNMPVAKEESVDDKWTRTTFEKSVPMSTYLVCFAVHQFDSVKRISNSGKPLTIYVQPEQK 241 Query: 277 NQADYALDAAVTLLEFYEDYFSIPYPLPKQDLAAIPDFQSGAMENWGLTTYRESALLFDA 336 + A+YA + ++ +++E+YF++ Y LPK D AIPDF +GAMENWGL TYRE+ LL+D Sbjct: 242 HTAEYAANITKSVFDYFEEYFAMNYSLPKLDKIAIPDFGTGAMENWGLITYRETNLLYDP 301 Query: 337 EKSSASSKLGITMTVAHELAHQWFGNLVTMEWWNDLWLNEGFAKFMEFVSVSVTHPELKV 396 ++S++S++ + VAHEL HQWFGN+VTM+WW DLWLNEGFA F EF+ V+ + ++ Sbjct: 302 KESASSNQQRVATVVAHELVHQWFGNIVTMDWWEDLWLNEGFASFFEFLGVNHAETDWQM 361 Query: 397 GD-YFFGKCFDAMEVDALNSSHPVSTPVENPAQIREMFDDVSYDKGACILNMLREYLSAD 455 D E D+L SSHP+ V P +I +FD +SY KG+ IL ML +++ + Sbjct: 362 RDQMLLEDVLPVQEDDSLMSSHPIIVTVTTPDEITSVFDGISYSKGSSILRMLEDWIKPE 421 Query: 456 AFKSGIVQYLQKHSYKNTKNEDLWDSMASICPTDGVKGMDGFCSRSQHSSSSSHWHQEGV 515 F+ G YL+K+ +KN K D W ++ + Sbjct: 422 NFQKGCQMYLEKYQFKNAKTSDFWAALEEASR---------------------------L 454 Query: 516 DVKTMMNTWTLQKGFPLITITVRGRNVHMKQ---EHYMKGSDGAPDTGYLWHVPLTFITS 572 VK +M+TWT Q G+P++ + +N+ K+ + S D GY W++P+ + Sbjct: 455 PVKEVMDTWTRQMGYPVLNVN-GVKNITQKRFLLDPRANPSQPPSDLGYTWNIPVKWTED 513 Query: 573 KSDMVHRFLLKTKTDVLI---LPEEVEWIKFNVGMNGYYIVHYEDDGWDSLTGLLKGTHT 629 F K + + P ++K N G+Y V+YE WDS+ L H Sbjct: 514 NITSSVLFNRSEKEGITLNSSNPSGNAFLKINPDHIGFYRVNYEVATWDSIATALSLNHK 573 Query: 630 AVSSNDRASLINNAFQLVSIGKLSIEKALDLSLYLKHETEIMPVF---QGLNELIPMYKL 686 SS DRASLI++AF L L + AL+L+ YLK E +P + +I M++ Sbjct: 574 TFSSADRASLIDDAFALARAQLLDYKVALNLTKYLKREENFLPWQRVISAVTYIISMFE- 632 Query: 687 MEKRDMNEVETQFKAFLIRLLRDLIDKQTWTDEGSVSERMLRSQLLLLACVHNYQPCVQR 746 D E+ + + ++ + D W D G ++LRS +L AC + + Sbjct: 633 ----DDKELYPMIEEYFQGQVKPIADSLGWNDAGDHVTKLLRSSVLGFACKMGDREALNN 688 Query: 747 AEGYFRKWKESNGNLSLPVDVTLAVFAVGAQSTEG---WDFLYSKYQFSLSSTEKSQIEF 803 A F +W NG +SLPV++ L V+ G Q++ W++ +YQ + + EK ++ + Sbjct: 689 ASSLFEQWL--NGTVSLPVNLRLLVYRYGMQNSGNEISWNYTLEQYQKTSLAQEKEKLLY 746 Query: 804 ALCRTQNKEKLQWLLDESFKGDKIKTQEFPQILTLIGRNPVGYPLAWQFLRKNWNKLVQK 863 L +N L LD + IKTQ+ ++ I N G +AW +++ NW+ LV + Sbjct: 747 GLASVKNVTLLSRYLDLLKDTNLIKTQDVFTVIRYISYNSYGKNMAWNWIQLNWDYLVNR 806 Query: 864 FELGSSSIAHMVMGTTNQFSTRTRLEEVKGFFSSLKENGSQLRCVQQTIETIEENIGWMD 923 + L + ++ +V F+T +L +++ FF+ + G+ + +Q +ET++ NI W+ Sbjct: 807 YTLNNRNLGRIVT-IAEPFNTELQLWQMESFFAKYPQAGAGEKPREQVLETVKNNIEWLK 865 Query: 924 KNFDKIRVWL 933 ++ + IR W Sbjct: 866 QHRNTIREWF 875 >4WZ9-A nrPDB Length = 957 Score = 787 bits (2033), Expect = 0.0, Method: Composition-based stats. Identities = 272/928 (29%), Positives = 432/928 (46%), Gaps = 79/928 (8%) Query: 50 NKIRLPEYVIPVHYDLLIHANL--TTLTFWGTTKVEITASQPTSTIILHSHHLQISRATL 107 + RLP IP+HYDL + + TF GT +++ Q T +++H+ L +S A + Sbjct: 44 ERYRLPTTSIPIHYDLHLRTEIHRNERTFTGTVGIQLQVVQATDKLVMHNRGLVMSSAKV 103 Query: 108 RK------GAGERLSEEPLQVLEHPRQEQIALLAPEPLLVGLPYTVVIHYAGNLSETFHG 161 GA + + +Q E I +P L G Y + + + G L+ G Sbjct: 104 SSLPNGVTGAPTLIGD--VQYSTDTTFEHITFTSPTILQPGT-YLLEVAFQGRLATNDDG 160 Query: 162 FYKSTYRTKEGELRILASTQFEPTAARMAFPCFDEPAFKASFSIKIRREPRHLAISNMPL 221 FY S+Y GE R LA+TQFE T+ARMAFPC+DEP KA+F++ I + AISNMP Sbjct: 161 FYVSSYVADNGERRYLATTQFESTSARMAFPCYDEPGLKATFTVSITHSLSYKAISNMPQ 220 Query: 222 VKSVTVAEGLIEDHFDVTVKMSTYLVAFIISDFESVSKITKSGVKVSVYAVPDKINQADY 281 + + + F+ T MSTYL+AF++SDF+ + SG + VY P+ N+A + Sbjct: 221 KTTTDIETDMRTTFFEKTPAMSTYLLAFVVSDFQ----LRLSGAQ-RVYVRPNAFNEATF 275 Query: 282 ALDAAVTLLEFYEDYFSIPYP--LPKQDLAAIPDFQSGAMENWGLTTYRESALLFDAEKS 339 AL+A V +L+ +D+ IPY +PK D AIPDF +GAMENWGL TYRE ALLF+ S Sbjct: 276 ALEAGVKILKVLDDHLGIPYDTYMPKLDQIAIPDFAAGAMENWGLVTYREQALLFNPAVS 335 Query: 340 SASSKLGITMTVAHELAHQWFGNLVTMEWWNDLWLNEGFAKFMEFVSVSVTHPELKVGDY 399 + K + T+AHE AHQWFGNLV+ EWW +WLNEGFA EF ++ + +P + + Sbjct: 336 TYRGKTNVATTIAHEYAHQWFGNLVSPEWWEYIWLNEGFATLYEFYALDMAYPGQEYWEL 395 Query: 400 FFGKCFD-AMEVDALNSSHPVSTPVENPAQIREMFDDVSYDKGACILNMLREYLSADAFK 458 F + AM D S+ P++ P +I +FD V+YDK +LNM+R L D +K Sbjct: 396 FNQQVIQYAMGQDGQASTRPMNWNAATPGEISALFDRVAYDKSGSVLNMMRHVLGDDNWK 455 Query: 459 SGIVQYLQKHSYKNTKNEDLWDSMASICPTDGVKGMDGFCSRSQHSSSSSHWHQEGVDVK 518 +G+ YL + + +E L+ + S GV GV V Sbjct: 456 AGLKAYLTDRALQGAVDEQLYAGLQSAIEGKGVL-------------------PNGVTVA 496 Query: 519 TMMNTWTLQKGFPLITI--TVRGRNVHMKQEHYMKGSDGAPDTGYLWHVPLTFITSKSDM 576 +M TWT + G+P++ + + +V + QE + P+T +W +P ++ Sbjct: 497 QIMRTWTNEAGYPVLNVRRSYDTGDVIISQERFYNDRK-VPNTN-IWMIPYNYVHQAKAD 554 Query: 577 VHRF----LLKTKTDVLILP-EEVEWIKFNVGMNGYYIVHYEDDGWDSLTGLLKGTHTAV 631 + F L TK + EWI FN GYY V+Y++ W+ +T L ++ Sbjct: 555 FNEFDDFQWLATKAARIETTVPANEWIVFNKQQVGYYRVNYDEHNWELITNALHENWASI 614 Query: 632 SSNDRASLINNAFQLVSIGKLSIEKALDLSLYLKHETEIMPVFQGLNELIPMYKLMEKRD 691 +RA LI++A+ L G+L + AL YL++E E P N + + R Sbjct: 615 HRLNRAQLIDDAYWLARSGRLDLRVALRFMTYLRNEREYAPWTAA-NVALTYFN-NRLRG 672 Query: 692 MNEVETQFKAFLIRLLRDLIDKQTWTDEGSVSERMLRSQLLLL----ACVHNYQPCVQRA 747 E F F+ L+ D+ T D S + +L L+ AC Y C+ + Sbjct: 673 TAEYH-NFLIFVDALIEDIYSLLT-IDAVSPDDTLLHKYLVQTISTWACSMGYTDCLMKT 730 Query: 748 EGYFRKWKESNGNLSLPVDVTLAVFAVGAQS--TEGWDFLYSKYQFSLSSTEKSQIEFAL 805 + G P D+ + G +S + +LY K S + E++ + +L Sbjct: 731 AALLKAEASGTGPAVHP-DIASVTYCYGMRSALESEFQYLYRKMMNSKNLAERTMLIDSL 789 Query: 806 CRTQNKEKLQWLLDESFKGD-----KIKTQEFPQILTLI-GRNPVGYPLAWQFLRKNWNK 859 + NKE L+ L + + E +++ I G +FL Sbjct: 790 GCSNNKEFLKAFLTTALGSGTGVEINYRADERRRVVQAIYSGGRTGVDALIEFLMD--PA 847 Query: 860 LVQKF--ELGSSSIAHMVMGTTNQFSTRTRLEEVKGFFSSL-----KENGSQLRCVQQTI 912 LV +F L +S++ + ++ + + ++ ++L + + LR Sbjct: 848 LVNEFVSTLSTSTLNSALSAIASRTNNVEEMNKLNALITALGSRVNSQTAANLRT----- 902 Query: 913 ETIEENIGWMDKNFDKIRVWLQSEKLER 940 T + N+ W++ + +E R Sbjct: 903 -TAQANLDWVNGFEGLMLSNFLAEAAAR 929 >1Z1W-A nrPDB Length = 780 Score = 579 bits (1493), Expect = e-165, Method: Composition-based stats. Identities = 218/819 (26%), Positives = 360/819 (43%), Gaps = 101/819 (12%) Query: 63 YDLLIHANLTTLTFWGTTKVEITASQPTSTIILHSHHLQISRATLRKGAGERLSEEPLQV 122 YDL + ++ TF GT + A I+L + LQI+ + G + + Q Sbjct: 6 YDLTLDFDIQKRTFNGTETITADAGD----IVLDAVGLQINWMKV-NGRDTAFTYDG-QT 59 Query: 123 LEHPRQEQIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRILASTQF 182 + P Q P + I +AG +S++ G Y + G + +T F Sbjct: 60 VRAPGDSQ-------------PQKIEISFAGKVSDSLSGIYYA------GRENGMITTHF 100 Query: 183 EPTAARMAFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGLIEDHFDVTVKM 242 E T AR FPC D PA+KA F+I + + + AISNMP K + V+E + F T +M Sbjct: 101 EATDARRMFPCVDHPAYKAVFAITVVIDKDYDAISNMP-PKRIEVSERKV-VEFQDTPRM 158 Query: 243 STYLVAFIISDFESVSKITKSGVKVSVYAVPDKINQADYALDAAVTLLEFYEDYFSIPYP 302 STYL+ I F + + + + K ++ Y LD A +EFYE+YF IPY Sbjct: 159 STYLLYVGIGKFRYEYEKYRD---IDLILASLKDIRSKYPLDMARKSVEFYENYFGIPYA 215 Query: 303 LPKQDLAAIPDFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVAHELAHQWFGN 362 LPK L ++P+F +GAMENWG T+RE + AE S+ + K +AHE+AHQWFG+ Sbjct: 216 LPKMHLISVPEFGAGAMENWGAITFREIYMDI-AENSAVTVKRNSANVIAHEIAHQWFGD 274 Query: 363 LVTMEWWNDLWLNEGFAKFMEFVSVSVTHPELKVG-DYFFGKCFDAMEVDALNSSHPVST 421 LVTM+WWNDLWLNE FA FM + ++ PE D+F + A+ D+L ++HP+ Sbjct: 275 LVTMKWWNDLWLNESFATFMSYKTMDTLFPEWSFWGDFFVSRTSGALRSDSLKNTHPIEV 334 Query: 422 PVENPAQIREMFDDVSYDKGACILNMLREYLSADAFKSGIVQYLQKHSYKNTKNEDLWDS 481 V +P +I ++FD++SY KGA IL M+ +Y + F+ GI +YL H + N + DLW + Sbjct: 335 DVRDPDEISQIFDEISYGKGASILRMIEDYAGYEEFRKGISKYLNDHKFGNAEGSDLWTA 394 Query: 482 MASICPTDGVKGMDGFCSRSQHSSSSSHWHQEGVDVKTMMNTWTLQKGFPLITITVRGRN 541 + + G VK +M W G+P+I + GR Sbjct: 395 IEDVS---------------------------GKPVKRVMEYWIKNPGYPVIKLKRNGRK 427 Query: 542 VHMKQEHYMKGSDGAPDTGYLWHVPLTFITSKSDMVHRFLLKTKTDVLILPEEVEWIKFN 601 + M Q ++ + + G W VP+ K D V R LL+ + + E IK N Sbjct: 428 ITMYQTRFLLNGE---EEGR-WPVPVNI--KKKDGVERILLEDEASI----EADGLIKIN 477 Query: 602 VGMNGYYIVHYEDDGWDSLTGLLKGTHTAVSSNDRASLINNAFQLVSIGKLSIEK-ALDL 660 G+Y V Y+D + + G + +S DR L+++ F + G + E + Sbjct: 478 ADSAGFYRVLYDDATFSDVM----GHYRDLSPLDRIGLVDDLFAFLLSGHIDPETYRQRI 533 Query: 661 SLYLKHETEIMPVFQGLNELIPMYKLMEKRDMNEVETQFKAFLIRLLRDLIDKQTWTDEG 720 + E V + + +++ ++ R + T + Sbjct: 534 RNFFDDEDHN--VITAIVGQMEYLRMLTHAFDDDA--------RAFCRSRMQFLTGKQDE 583 Query: 721 SVSERMLRSQLLLLACVHNYQPCVQRAEGYFRKWKESNGNLSLPVDVTLAVFAVGAQSTE 780 ++ + R L + +Y F+ + S ++ ++ A T Sbjct: 584 NLKIALGRVSRLYVMVDESYAE---EMSKLFKDF------DSAEPEMRSSIATAYALVTG 634 Query: 781 GWDFLYSKYQFSLSSTEKSQIEFALCRTQNKEKLQWLLDESFKGDKIKTQEFPQILTLIG 840 L K++ ++ +I A + ++ L + K + IK Q+ + Sbjct: 635 DLKGLLEKFRSVDRDEDRVRIISAFGKLKSNTDLSTVYGMVEKTE-IKKQDMISFFSSAL 693 Query: 841 RNPVGYPLAWQFLRKNWN---KLVQKFELGSSSIAHMVM 876 G +F+ N + +LV ++ G+ + + V Sbjct: 694 ETLPGR----EFIFANLDRIIRLVIRYFTGNRTASRTVE 728 >3RJO-A nrPDB Length = 419 Score = 571 bits (1472), Expect = e-163, Method: Composition-based stats. Identities = 413/413 (100%), Positives = 413/413 (100%) Query: 529 GFPLITITVRGRNVHMKQEHYMKGSDGAPDTGYLWHVPLTFITSKSDMVHRFLLKTKTDV 588 GFPLITITVRGRNVHMKQEHYMKGSDGAPDTGYLWHVPLTFITSKSDMVHRFLLKTKTDV Sbjct: 1 GFPLITITVRGRNVHMKQEHYMKGSDGAPDTGYLWHVPLTFITSKSDMVHRFLLKTKTDV 60 Query: 589 LILPEEVEWIKFNVGMNGYYIVHYEDDGWDSLTGLLKGTHTAVSSNDRASLINNAFQLVS 648 LILPEEVEWIKFNVGMNGYYIVHYEDDGWDSLTGLLKGTHTAVSSNDRASLINNAFQLVS Sbjct: 61 LILPEEVEWIKFNVGMNGYYIVHYEDDGWDSLTGLLKGTHTAVSSNDRASLINNAFQLVS 120 Query: 649 IGKLSIEKALDLSLYLKHETEIMPVFQGLNELIPMYKLMEKRDMNEVETQFKAFLIRLLR 708 IGKLSIEKALDLSLYLKHETEIMPVFQGLNELIPMYKLMEKRDMNEVETQFKAFLIRLLR Sbjct: 121 IGKLSIEKALDLSLYLKHETEIMPVFQGLNELIPMYKLMEKRDMNEVETQFKAFLIRLLR 180 Query: 709 DLIDKQTWTDEGSVSERMLRSQLLLLACVHNYQPCVQRAEGYFRKWKESNGNLSLPVDVT 768 DLIDKQTWTDEGSVSERMLRSQLLLLACVHNYQPCVQRAEGYFRKWKESNGNLSLPVDVT Sbjct: 181 DLIDKQTWTDEGSVSERMLRSQLLLLACVHNYQPCVQRAEGYFRKWKESNGNLSLPVDVT 240 Query: 769 LAVFAVGAQSTEGWDFLYSKYQFSLSSTEKSQIEFALCRTQNKEKLQWLLDESFKGDKIK 828 LAVFAVGAQSTEGWDFLYSKYQFSLSSTEKSQIEFALCRTQNKEKLQWLLDESFKGDKIK Sbjct: 241 LAVFAVGAQSTEGWDFLYSKYQFSLSSTEKSQIEFALCRTQNKEKLQWLLDESFKGDKIK 300 Query: 829 TQEFPQILTLIGRNPVGYPLAWQFLRKNWNKLVQKFELGSSSIAHMVMGTTNQFSTRTRL 888 TQEFPQILTLIGRNPVGYPLAWQFLRKNWNKLVQKFELGSSSIAHMVMGTTNQFSTRTRL Sbjct: 301 TQEFPQILTLIGRNPVGYPLAWQFLRKNWNKLVQKFELGSSSIAHMVMGTTNQFSTRTRL 360 Query: 889 EEVKGFFSSLKENGSQLRCVQQTIETIEENIGWMDKNFDKIRVWLQSEKLERM 941 EEVKGFFSSLKENGSQLRCVQQTIETIEENIGWMDKNFDKIRVWLQSEKLERM Sbjct: 361 EEVKGFFSSLKENGSQLRCVQQTIETIEENIGWMDKNFDKIRVWLQSEKLERM 413 >5DLL-A nrPDB Length = 867 Score = 423 bits (1086), Expect = e-118, Method: Composition-based stats. Identities = 108/492 (21%), Positives = 187/492 (38%), Gaps = 67/492 (13%) Query: 91 STIILHSHHLQISRATLRKGAGERLSEEPLQVLEHPRQEQIALLAPEPLLVGLPYTVVIH 150 +T++L L++ L + + L E E ++ P L V I+ Sbjct: 60 NTLVLDGVELKLLSIKL--------NNKHLSPAEFAVNENQLIINNVPEKFVLQTVVEIN 111 Query: 151 YAGNLSETFHGFYKSTYRTKEGELRILASTQFEPTAARMAFPCFDEPAFKASFSIKIRRE 210 + N + G YKS + STQ E T R D P A+F++KI + Sbjct: 112 PSAN--TSLEGLYKSG---------DVFSTQCEATGFRKITYYLDRPDVMAAFTVKIIAD 160 Query: 211 P--RHLAISNMPLVKSVTVAEGLIEDHFDVTVKMSTYLVAFIISDFESVSKI----TKSG 264 + +SN + S +++ + K YL A + D S+ ++ Sbjct: 161 KKKYPIILSNGDKIDSGDISDNQHFAVWKDPFKKPCYLFALVAGDLASIKDTYITKSQRK 220 Query: 265 VKVSVYAVPDKINQADYALDAAVTLLEFYEDYFSIPYPLPKQDLAAIPDFQSGAMENWGL 324 V + +YA I++ YA+ A +++ ED F + Y L + A+PDF +GAMEN GL Sbjct: 221 VSLEIYAFKQDIDKCHYAMQAVKDSMKWDEDRFGLEYDLDTFMIVAVPDFNAGAMENKGL 280 Query: 325 TTYRESALLFDAEKSSASSKLGITMTVAHELAHQWFGNLVTMEWWNDLWLNEGFAKF--M 382 + ++ + ++ + V HE H W G+ VT W L L EG F Sbjct: 281 NIFNTKYIMASNKTATDKDFELVQSVVGHEYFHNWTGDRVTCRDWFQLSLKEGLTVFRDQ 340 Query: 383 EFVSVSVTHPELKVGDYFFGKCFDAMEVDALNSSHPVSTPVENPAQIREMFDDVSYDKGA 442 EF S + ++ D + E DA SHP+ E+ ++ + Y+KGA Sbjct: 341 EFTSDLNSRDVKRIDDVRIIRSAQFAE-DASPMSHPIRP--ESYIEMNNFYTVTVYNKGA 397 Query: 443 CILNMLREYLSADAFKSGIVQYLQKHSYKNTKNEDLWDSMASICPTDGVKGMDGFCSRSQ 502 I+ M+ L + F+ G+ Y ++H + +D ++MA D Sbjct: 398 EIIRMIHTLLGEEGFQKGMKLYFERHDGQAVTCDDFVNAMADANNRDF------------ 445 Query: 503 HSSSSSHWHQEGVDVKTMMNTWTLQKGFPLITITVR------GRNVHMKQEHYMKGSDGA 556 ++ W Q G P I ++ ++ ++Q Sbjct: 446 ----------------SLFKRWYAQSGTPNIKVSENYDASSQTYSLTLEQTTL---PTAD 486 Query: 557 PDTGYLWHVPLT 568 H+P+ Sbjct: 487 QKEKQALHIPVK 498 >4Q4I-A nrPDB Length = 891 Score = 391 bits (1005), Expect = e-109, Method: Composition-based stats. Identities = 104/501 (20%), Positives = 174/501 (34%), Gaps = 74/501 (14%) Query: 52 IRLPEYVIPVHYDLLIHANLTTLTFWG-TTKVEITASQPTSTIILHSHHLQISRATLRKG 110 R P+Y I DL + + V AS + Sbjct: 34 YRAPDYQITD-IDLTFDLDAQKTVVTAVSQAVRHGASDAP-----------------LRL 75 Query: 111 AGERLSEEPLQVLEHP-----RQEQIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKS 165 GE L + + + P +E +++ P L I A N + G Y+S Sbjct: 76 NGEDLKLVSVHINDEPWTAWKEEEGALVISNLPERFTLKIINEISPAANTA--LEGLYQS 133 Query: 166 TYRTKEGELRILASTQFEPTAARMAFPCFDEPAFKASFSIKIRREP--RHLAISNMPLVK 223 TQ E R D P A F+ KI + +SN V Sbjct: 134 GDA---------LCTQCEAEGFRHITYYLDRPDVLARFTTKIIADKIKYPFLLSNGNRVA 184 Query: 224 SVTVAEGLIEDHFDVTVKMSTYLVAFIISDFESVSKI--TKSGVKV--SVYAVPDKINQA 279 + G + YL A + DF+ + T+SG +V +Y +++A Sbjct: 185 QGELENGRHWVQWQDPFPKPCYLFALVAGDFDVLRDTFTTRSGREVALELYVDRGNLDRA 244 Query: 280 DYALDAAVTLLEFYEDYFSIPYPLPKQDLAAIPDFQSGAMENWGLTTYRESALLFDAEKS 339 +A+ + +++ E+ F + Y L + A+ F GAMEN GL + +L + + Sbjct: 245 PWAMTSLKNSMKWDEERFGLEYDLDIYMIVAVDFFNMGAMENKGLNIFNSKYVLARTDTA 304 Query: 340 SASSKLGITMTVAHELAHQWFGNLVTMEWWNDLWLNEGFAKF--MEFVSVSVTHPELKVG 397 + L I + HE H W GN VT W L L EG F EF S + ++ Sbjct: 305 TDKDYLDIERVIGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDLGSRAVNRIN 364 Query: 398 DYFFGKCFDAMEVDALNSSHPVSTPVENPAQIREMFDDVSYDKGACILNMLREYLSADAF 457 + + E DA +HP+ + ++ + Y+KGA ++ M+ L + F Sbjct: 365 NVRTMRGLQFAE-DASPMAHPIRPDMV--IEMNNFYTLTVYEKGAEVIRMIHTLLGEENF 421 Query: 458 KSGIVQYLQKHSYKNTKNEDLWDSMASICPTDGVKGMDGFCSRSQHSSSSSHWHQEGVDV 517 + G+ Y ++H +D + +S+ H Sbjct: 422 QKGMQLYFERHDGSAATCDDF-------------------VQAMEDASNVDLSH------ 456 Query: 518 KTMMNTWTLQKGFPLITITVR 538 W Q G P++T+ Sbjct: 457 ---FRRWYSQSGTPIVTVKDD 474 >4QHP-A nrPDB Length = 870 Score = 390 bits (1001), Expect = e-108, Method: Composition-based stats. Identities = 109/570 (19%), Positives = 185/570 (32%), Gaps = 83/570 (14%) Query: 50 NKIRLPEYVIPVHYDLLIHANLTTLTFWGTTKVEITASQPTSTIILHSHHLQISRATLRK 109 + P Y I + DL N VE ++ + Sbjct: 12 KDYQTPAYHI-LKTDLHFDINEPQTVVKSRLTVEPQ---------------RVGEPLVLD 55 Query: 110 GAGERLSEEPLQVLEHPRQEQIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRT 169 G+ + LS + E L V +++ G Y S Sbjct: 56 GSAKLLSVKINGAAADYVLEGETLTIAGVPSERFTVEVETEILPAENKSLMGLYAS---- 111 Query: 170 KEGELRILASTQFEPTAARMAFPCFDEPAFKASFSIKIRREP--RHLAISNMPLVKSVTV 227 G TQ EP R D P + F+ I + + +SN + Sbjct: 112 -GGN----LFTQCEPEGFRKITFYIDRPDVMSKFTTTIVADKKRYPVLLSNGNKIDGGEF 166 Query: 228 AEGLIEDHFDVTVKMSTYLVAFIISDF----ESVSKITKSGVKVSVYAVPDKINQADYAL 283 ++G ++ +YL A + D + + ++ VK+ Y + +A+ Sbjct: 167 SDGRHWVKWEDPFSKPSYLFALVAGDLAVTEDYFTTMSGRNVKIEFYTTEADKPKVGFAV 226 Query: 284 DAAVTLLEFYEDYFSIPYPLPKQDLAAIPDFQSGAMENWGLTTYRESALLFDAEKSSASS 343 ++ +++ E F + Y L + A+ DF GAMEN GL + +L D+ ++ + Sbjct: 227 ESLKNAMKWDETRFGLEYDLDIFMVVAVGDFNMGAMENKGLNIFNTKFVLADSRTATDTD 286 Query: 344 KLGITMTVAHELAHQWFGNLVTMEWWNDLWLNEGFAKF--MEFVSVSVTHPELKVGDYFF 401 GI V HE H W GN VT W L L EG F EF + ++ + Sbjct: 287 FEGIESVVGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSGDRASRAVRRIENIRL 346 Query: 402 GKCFDAMEVDALNSSHPVSTPVENPAQIREMFDDVSYDKGACILNMLREYLSADAFKSGI 461 + E DA ++HPV + ++ + Y+KGA ++ M L + F+ G+ Sbjct: 347 LRQHQFPE-DAGPTAHPVRPA--SYEEMNNFYTMTVYEKGAEVVRMYHTLLGEEGFQKGM 403 Query: 462 VQYLQKHSYKNTKNEDLWDSMASICPTDGVKGMDGFCSRSQHSSSSSHWHQEGVDVKTMM 521 Y Q+H + +D +MA + Sbjct: 404 KLYFQRHDGQAVTCDDFRAAMADANGINL----------------------------DQF 435 Query: 522 NTWTLQKGFPLITITVRGRN----VHMKQEHYMKGSDGAPDTGYLWHVPLT--------- 568 W Q G P++ R +N + +KQ +P+ Sbjct: 436 ALWYSQAGTPVLEAEGRLKNNIFELTVKQT---VPPTPDMTDKQPMMIPVKVGLLNRNGE 492 Query: 569 ---FITSKSDMVHRFLLKTKTDVLILPEEV 595 F LL T+ + L E V Sbjct: 493 AVAFDYQGKRATEAVLLLTEAEQTFLLEGV 522 >5Y1X-A nrPDB Length = 914 Score = 362 bits (930), Expect = e-100, Method: Composition-based stats. Identities = 150/848 (17%), Positives = 286/848 (33%), Gaps = 124/848 (14%) Query: 58 VIPVHYDLLIHANLTTLTFWGTTKVEITASQPTSTIILHSHHLQISRATLRKGAGERLSE 117 + V ++ IH N T ++I+ ++ L+I+ ++ Sbjct: 40 INNVTLNINIHDNET--IVRSVLDMDISKHNVGEDLVFDGVGLKINEI--------SINN 89 Query: 118 EPLQVLEHPRQEQIALLAPEPLLVGLPY----TVVIHYAGNLSETFHGFYKSTYRTKEGE 173 + L E + L + + V+IH N + G YKS Sbjct: 90 KKLVEGEEYTYDNEFLTIFSKFVPKSKFAFSSEVIIHPETNYA--LTGLYKS-------- 139 Query: 174 LRILASTQFEPTAARMAFPCFDEPAFKASFSIKIRREP--RHLAISNMPLVKSVTVAEGL 231 + + +Q E T R D P A + + + + + +SN V + G Sbjct: 140 -KNIIVSQCEATGFRRITFFIDRPDMMAKYDVTVTADKEKYPVLLSNGDKVNEFEIPGGR 198 Query: 232 IEDHFDVTVKMSTYLVAFIISDFE-----SVSKITKSGVKVSVYAVPDKINQADYALDAA 286 F+ YL A + D + ++K TK V++ V++ +++ +AL+ Sbjct: 199 HGARFNDPHLKPCYLFAVVAGDLKHLSATYITKYTKKKVELYVFSEEKYVSKLQWALECL 258 Query: 287 VTLLEFYEDYFSIPYPLPKQDLAAIPDFQSGAMENWGLTTYRESALLFDAEKSSASSKLG 346 + F EDYF + Y L + +L A+ DF GAMEN GL + ++LL + S S Sbjct: 259 KKSMAFDEDYFGLEYDLSRLNLVAVSDFNVGAMENKGLNIFNANSLLASKKNSIDFSYAR 318 Query: 347 ITMTVAHELAHQWFGNLVTMEWWNDLWLNEGFAKFME--FVSVSVTHPELKVGDYFFGKC 404 I V HE H + GN VT+ W L L EG E F ++ + Sbjct: 319 ILTVVGHEYFHNYTGNRVTLRDWFQLTLKEGLTVHRENLFSEEMTKTVTTRLSHVDLLRS 378 Query: 405 FDAMEVDALNSSHPVSTPVENPAQIREMFDDVSYDKGACILNMLREYLSADAFKSGIVQY 464 +E D+ SHP+ E+ + + YDKG+ ++ M L + +K G Y Sbjct: 379 VQFLE-DSSPLSHPIRP--ESYVSMENFYTTTVYDKGSEVMRMYLTILGEEYYKKGFDIY 435 Query: 465 LQKHSYKNTKNEDLWDSMASICPTDGVKGMDGFCSRSQHSSSSSHWHQEGVDVKTMMNTW 524 ++K+ ED +M W Sbjct: 436 IKKNDGNTATCEDFNYAMEQAYKMKKADNSANLNQYLL---------------------W 474 Query: 525 TLQKGFPLITITVR----GRNVHMKQEHYMKGSDGAPDTGYLWHVPLTF----ITSKSDM 576 Q G P ++ + + Y K + + L+ +P++ + +M Sbjct: 475 FSQSGTPHVSFKYNYDAEKKQYSIHVNQYTKPDENQKEKKPLF-IPISVGLINPENGKEM 533 Query: 577 VHRFLLK-TKTDVLI--------------------------LPEEVEWIKFNVGMNGYYI 609 + + L+ TK L +E + + + Sbjct: 534 ISQTTLELTKESDTFVFNNIAVKPIPSLFRGFSAPVYIEDNLTDEERILLLKYDSDAFVR 593 Query: 610 VH-----YEDD---GWDSLTGLLKGTHTA--VSSNDRASLINNAFQL-----VSIGKLSI 654 + Y ++ + ++ + A I+ L G S Sbjct: 594 YNSCTNIYMKQILMNYNEFLKAKNEKLESFNLTPVN-AQFIDAIKYLLEDPHADAGFKSY 652 Query: 655 EKALDLSLYLKHETEIMPVFQGLNELIPMYKLMEKRDMNEVETQFKAFLIRLLRDL--ID 712 +L Y+ + + + +YK + + +N+V + L DL + Sbjct: 653 IVSLPQDRYIINFVSNLDTDVLADTKEYIYKQIGDK-LNDVYYKMFKSLEAKADDLTYFN 711 Query: 713 KQTWTDEGSVSERMLRSQLLLLACVHNYQPCVQRA-----EGYFRKWKESNGNLSLPVDV 767 ++ D ++ R LR+ LL L Y + Y W S ++S D Sbjct: 712 DESHVDFDQMNMRTLRNTLLSLLSKAQYPNILNEIIEHSKSPYPSNWLTSL-SVSAYFDK 770 Query: 768 TLAVFAVGAQSTEGWDFLYSKYQFSLSSTEKSQIEFALCRTQNKEKLQWLLDESFKGDKI 827 ++ + ++ + L ++ ++S +++ I L K+ +L +S + I Sbjct: 771 YFELYDKTYKLSKDDELLLQEWLKTVSRSDRKDIYEIL-----KKLENEVLKDSKNPNDI 825 Query: 828 KTQEFPQI 835 + P Sbjct: 826 RAVYLPFT 833 >5FWQ-A nrPDB Length = 633 Score = 346 bits (887), Expect = 3e-95, Method: Composition-based stats. Identities = 95/433 (21%), Positives = 168/433 (38%), Gaps = 32/433 (7%) Query: 62 HYDLLIHANLTTLTFWGTTKVEITASQPT-STIILHSHHLQISRATLRKGAGERLSEEPL 120 H L + T T GT + + + + +++L + L I + + G + + Sbjct: 35 HLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVI-NGQEVKYALGER 93 Query: 121 QVLEHPRQEQIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRILAST 180 Q + E + P L + I + S T G+ + Sbjct: 94 QSYKGSPME---ISLPIALSKNQEIVIEISFET--SPKSSALQWLTPEQTSGKEHPYLFS 148 Query: 181 QFEPTAARMAFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGLIEDH----F 236 Q + R PC D P+ K +++ ++ +A+ M ++ + F Sbjct: 149 QCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVAL--MSAIRDGETPDPEDPSRKIYKF 206 Query: 237 DVTVKMSTYLVAFIISDFESVSKITKSGVKVSVYAVPDKINQADYALDAAVTLLEFYEDY 296 V + YL+A ++ ES + G + V++ +++ ++ Y ++L+ ED Sbjct: 207 IQKVPIPCYLIALVVGALES----RQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAED- 261 Query: 297 FSIPYPLPKQDLAAIP-DFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVAHEL 355 PY + DL +P F G MEN LT + L D S +AHE+ Sbjct: 262 LGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLS---------NVIAHEI 312 Query: 356 AHQWFGNLVTMEWWNDLWLNEGFAKFMEFVSVSVTHPEL-KVGDYFFGKCFDAMEVDALN 414 +H W GNLVT + W+ WLNEG ++E E + + G V Sbjct: 313 SHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFG 372 Query: 415 SSHPVSTPVENPAQIRE--MFDDVSYDKGACILNMLREYLSADAFKSGIVQ-YLQKHSYK 471 +HP + V + I + V Y+KG +L L + L G ++ Y++K SYK Sbjct: 373 ETHPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYK 432 Query: 472 NTKNEDLWDSMAS 484 + +D D + S Sbjct: 433 SITTDDWKDFLYS 445 >5ZI5-A nrPDB Length = 921 Score = 345 bits (884), Expect = 6e-95, Method: Composition-based stats. Identities = 92/455 (20%), Positives = 170/455 (37%), Gaps = 45/455 (9%) Query: 61 VHYDLLIHANLTTLTFWGTTKVEITASQPTSTIILHSHHLQISRATLRKGAGERLSEEPL 120 +H DL I + + V P + HS+ L + GE ++ L Sbjct: 50 IHVDLQIDLSKKPVESKARLTVV-----PNLNVDSHSNDLVLD--------GENMTLVSL 96 Query: 121 QVLEHPRQEQIALLAPEPLLV-----GLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELR 175 Q+ ++ +E L + L++ P+T+ + + G Y++ Sbjct: 97 QMNDNLLKENEYELTKDSLIIKNIPQNTPFTIEMTSLLGENTDLFGLYETE--------- 147 Query: 176 ILASTQFEPTAARMAFPCFDEPAFKASFSIKIR--REPRHLAISNMPLVKSVTVAEGLIE 233 +A + E R F D P A++ I +E + +SN L++ + GL Sbjct: 148 GVALVKAESEGLRRVFYLPDRPDNLATYKTTIIANQEDYPVLLSNGVLIEKKELPLGLHS 207 Query: 234 DHFDVTVKMSTYLVAFIISDFE--SVSKITKSGV--KVSVYAVPDKINQADYALDAAVTL 289 + V +YL A + + + TKSG + Y P ++ D+A + Sbjct: 208 VTWLDDVPKPSYLFALVAGNLQRSVTYYQTKSGRELPIEFYVPPSATSKCDFAKEVLKEA 267 Query: 290 LEFYEDYFSIPYPLPKQDLAAIPDFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITM 349 + + E F++ L + +A + + SGA E GL + L E + L + Sbjct: 268 MAWDERTFNLECALRQHMVAGVDKYASGASEPTGLNLFNTENLFASPETKTDLGILRVLE 327 Query: 350 TVAHELAHQWFGNLVTMEWWNDLWLNEGFAKFMEFVSVSVTHPELKVGDYFFGKCFDAME 409 VAHE H W G+ VT+ W +L L EG F ++ EL D + D Sbjct: 328 VVAHEFFHYWSGDRVTIRDWFNLPLKEGLTTF----RAAMFREELFGTDLI--RLLDGKN 381 Query: 410 VDALNSSHPVSTPVENPAQIREMFDDVSYDKGACILNMLREYLSADAFKSGIVQYLQKHS 469 +D T V + ++ +Y+K A I M+ ++ + F + ++ + + Sbjct: 382 LDERAPRQSAYTAVRS------LYTAAAYEKSADIFRMMMLFIGKEPFIEAVAKFFKDND 435 Query: 470 YKNTKNEDLWDSMASICPTDGVKGMDGFCSRSQHS 504 ED +S+++ D + F Sbjct: 436 GGAVTLEDFIESISNSSGKDLRSFLSWFTESGIPE 470 >4GAA-A nrPDB Length = 609 Score = 329 bits (842), Expect = 5e-90, Method: Composition-based stats. Identities = 96/440 (21%), Positives = 174/440 (39%), Gaps = 32/440 (7%) Query: 55 PEYVIPVHYDLLIHANLTTLTFWGTTKVEI-TASQPTSTIILHSHHLQISRATLRKGAGE 113 PE H L +H + T+ +T + + + +++IL + L I + + G Sbjct: 10 PEKFNIKHMHLKLHVDFTSRAIAASTSLTVRSLQDSLASLILDTKDLTIKKVAV-NGKDA 68 Query: 114 RLSEEPLQVLEHPRQEQIALLAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGE 173 + + E + P L G V I S G+ Sbjct: 69 TFALGTTHSFKGTPLE---ITLPFSLTRGQEVIVEIDSVT--SPKSSALQWLNKEQTAGK 123 Query: 174 LRILASTQFEPTAARMAFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGLIE 233 + +Q + T R PC D P+ K ++ ++ +A+ M ++ ++E Sbjct: 124 IHPYLFSQCQATHCRSIIPCQDTPSVKFTYYSQVSVPKELMAL--MSALRDGELSEQSDS 181 Query: 234 DH----FDVTVKMSTYLVAFIISDFESVSKITKSGVKVSVYAVPDKINQADYALDAAVTL 289 + F V + +YL+A ++ E K G + +++ + + + Y + Sbjct: 182 NRKIYRFKQNVPIPSYLIALVVGALEG----RKVGPRTTIWTEKELLEPSVYEFAETEKM 237 Query: 290 LEFYEDYFSIPYPLPKQDLAAIP-DFQSGAMENWGLTTYRESALLFDAEKSSASSKLGIT 348 L++ ED + PY + DL +P F G MEN LT + L D +S Sbjct: 238 LKYAED-LAGPYVWGQYDLLILPPSFPYGGMENPCLTFVTPTVLAGDRSLAS-------- 288 Query: 349 MTVAHELAHQWFGNLVTMEWWNDLWLNEGFAKFMEFVSVSVTH-PELKVGDYFFGKCFDA 407 +AHE++H W GNLVT E W + WLNEG ++E + E + G Sbjct: 289 -VIAHEISHSWTGNLVTNETWENFWLNEGHTVYLERRIDGRLYGEEFRQFKALGGWKELQ 347 Query: 408 MEVDALNSSHPVSTPVEN--PAQIREMFDDVSYDKGACILNMLREYLSADAFKSGIVQ-Y 464 V+ +++P++ V N + F V Y+KG +L L + L G ++ Y Sbjct: 348 NSVNTFGATNPLTNLVPNLHEVDVDAAFSSVPYEKGFALLFYLEQLLGGPEIFLGFLKSY 407 Query: 465 LQKHSYKNTKNEDLWDSMAS 484 +Q ++K+ E+ + S Sbjct: 408 IQMFAFKSVTTEEWKKFLYS 427 >2XPY-A nrPDB Length = 632 Score = 311 bits (796), Expect = 1e-84, Method: Composition-based stats. Identities = 93/444 (20%), Positives = 164/444 (36%), Gaps = 47/444 (10%) Query: 61 VHYDLLIHANLTTLTFWGTTKVEI----TASQPTSTIILHSHHLQISRATLRKGAGERLS 116 +H DL + + G+ ++ + + L + +L + + + Sbjct: 31 LHTDLNLSVSFEKSAISGSVTFQLKKLHEGKNKSDELHLDTSYLDVQEVHIDGSKADFQI 90 Query: 117 EEPLQVLEHPRQEQIALLAPEPLLVGLPYTVVIHYAGNLSETFHGF-YKSTYRTKEGELR 175 E+ + L ++ +T+ I + ++ + ++ +TK G+ Sbjct: 91 EQRKEPL-----GSRLVINNASC--NDNFTLNIQF--RTTDKCTALQWLNSKQTKGGKPY 141 Query: 176 ILASTQFEPTAARMAFPCFDEPAFKASFSIKIRREPRHLAISNMPLVKSVTVAEGLIED- 234 + +Q E AR FPCFD P+ K++F+ I S +P+V S E +D Sbjct: 142 VF--SQLEAIHARSLFPCFDTPSVKSTFTASIE--------SPLPVVFSGIRIEDTSKDT 191 Query: 235 ---HFDVTVKMSTYLVAFIISDFESVSKITKSGVKVSVYAVPDKINQADYALDAAVTLLE 291 F+ V + YL+ D S G + +VY P ++ + + V Sbjct: 192 NIYRFEQKVPIPAYLIGIASGDLSSAP----IGPRSTVYTEPFRLKDCQWEFENDVEKFI 247 Query: 292 FYEDYFSIPYPLPKQD-LAAIPDFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMT 350 + Y D L + + G ME+ +T + + D Sbjct: 248 QTAEKIIFEYEWGTYDILVNVDSYPYGGMESPNMTFATPTLIAHDRSN---------IDV 298 Query: 351 VAHELAHQWFGNLVTMEWWNDLWLNEGFAKFMEFVSVSVTHPE-LKVGDYFFGKCFDAME 409 +AHELAH W GNLVT WN WLNEG+ ++E + H E + G Sbjct: 299 IAHELAHSWSGNLVTNCSWNHFWLNEGWTVYLERRIIGAIHGEPTRHFSALIGWSDLQNS 358 Query: 410 VDALNSSHPVSTPVE---NPAQIREMFDDVSYDKGACILNMLREYLSAD-AFKSGIVQYL 465 +D++ ST V+ + + F V Y+KG +L L L F I Y Sbjct: 359 IDSMKDPERFSTLVQNLNDNTDPDDAFSTVPYEKGFNLLFHLETILGGKAEFDPFIRHYF 418 Query: 466 QKHSYKNTKNEDLWDSMASICPTD 489 +K + K+ D++ P Sbjct: 419 KKFAKKSLDTFQFLDTLYEFYPEK 442 >3CIA-A nrPDB Length = 605 Score = 292 bits (748), Expect = 4e-79, Method: Composition-based stats. Identities = 92/474 (19%), Positives = 179/474 (37%), Gaps = 43/474 (9%) Query: 33 QSTEASPKRSDGTPFPWNKIRLPEYVIPVHYDLLIHANLTTLTFWGTTKVEIT-ASQPTS 91 + + + + + + V H L ++ + + G ++ + + + Sbjct: 4 ATHQHANVSKLTDAYTYANY---DQVKATHVYLDLNVDFDKKSLSGFAELSLDWFTDNKA 60 Query: 92 TIILHSHHLQISRATLRKGAGERLS-EEPLQVLEHPRQEQIALLAPEPLLVGLPYTVVIH 150 +IL + L I R + G+ + L + ++ + P Y Sbjct: 61 PLILDTRDLVIHRVMAKNSQGQWVKVNYDLAKRDDVLGSKLTINTPLNAKKVRVYY---- 116 Query: 151 YAGNLSETFHGFYKSTYRTKEGELRILASTQFEPTAARMAFPCFDEPAFKASFSIKIRRE 210 N +E G + G+ + +Q + AR P D P+ + +++ +I + Sbjct: 117 ---NSTEKATGLQWLSAEQTAGKEKPFLFSQNQAIHARSWIPIQDTPSVRVTYTARITTD 173 Query: 211 PRHLAISNMPLVKSVTVAEGLIED---HFDVTVKMSTYLVAFIISDFESVSKITKSGVKV 267 LA V S G D F + + YL+A + D E + ++G+ Sbjct: 174 KDLLA------VMSANNEPGTERDGDYFFSMPQAIPPYLIAIGVGDLEFKAMSHQTGIYA 227 Query: 268 SVYAVPDKINQADYALDAAVTLLEFYEDYFSIPYPLPKQDLAAIP-DFQSGAMENWGLTT 326 Y + + + D +++ E + Y + DL +P F G MEN L+ Sbjct: 228 ESYILDAAVAE----FDDTQAMIDKAEQMYG-KYRWGRYDLLMLPPSFPFGGMENPRLSF 282 Query: 327 YRESALLFDAEKSSASSKLGITMTVAHELAHQWFGNLVTMEWWNDLWLNEGFAKFME-FV 385 + + D + +AHELAH W GNLVT E W DLWLNEGF ++E + Sbjct: 283 ITPTVVAGDKS---------LVNLIAHELAHSWSGNLVTNESWRDLWLNEGFTSYVENRI 333 Query: 386 SVSVTHPELKVGDYFFGK---CFDAMEVDALNSSHPVSTPVENPAQIREMFDDVSYDKGA 442 +V + V + G + +E+DA ++ + +P + F V Y KG Sbjct: 334 MEAVFGTDRAVMEQALGAQDLNAEILELDASDTQLYIDLKGRDP---DDAFSGVPYVKGQ 390 Query: 443 CILNMLREYLSADAFKSGIVQYLQKHSYKNTKNEDLWDSMASICPTDGVKGMDG 496 L L E + F + +++Y H++++ ++ + + + Sbjct: 391 LFLMYLEEKFGRERFDAFVLEYFDSHAFQSLGTDNFVKYLKANLTDKYPNIVSD 444 >3ZUK-A nrPDB Length = 699 Score = 36.0 bits (81), Expect = 0.073, Method: Composition-based stats. Identities = 19/65 (29%), Positives = 29/65 (44%), Gaps = 16/65 (24%) Query: 321 NWGLT-TYRESALL----FDAEKSSASSKLGITMTVAHELAHQW---------FGNLVTM 366 N G+ +A+L FD + A++ GI + HE+ H + GNLV Sbjct: 492 NPGMNEIVFPAAILQPPFFDPQADEAANYGGIGAVIGHEIGHGFDDQGAKYDGDGNLV-- 549 Query: 367 EWWND 371 +WW D Sbjct: 550 DWWTD 554 >4XBH-A nrPDB Length = 696 Score = 35.2 bits (79), Expect = 0.13, Method: Composition-based stats. Identities = 22/105 (20%), Positives = 37/105 (35%), Gaps = 25/105 (23%) Query: 314 FQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVAHELAH---------QWFGNLV 364 F +G ++ F A++S++ + GI M + HE+ H G+LV Sbjct: 501 FPAGILQPP----------FFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLV 550 Query: 365 TMEWWNDLWLNEGFAKFMEFVSVSVTHPELKVGDYFFGKCFDAME 409 +WW N F E V D G+ + + Sbjct: 551 --DWWTQQSAN----NFKEQSQCMVYQYGNFSWDLAGGQHLNGIN 589 >3MDV-A nrPDB Length = 456 Score = 34.8 bits (78), Expect = 0.17, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 25/72 (34%) Query: 392 PELKVGDYFFGKCFDAMEVDALNSSHPVSTPVENPAQIREMFDDVSYDKGACILNMLREY 451 + D F V +N H S V +P +++ Y+K + + L+ Sbjct: 8 GGRVLQDVFLDWAKKYGPVVRVNVFHKTSVIVTSPESVKKFLMSTKYNKDSKMYRALQTV 67 Query: 452 LSADAFKSGIVQ 463 F G+V Sbjct: 68 FGERLFGQGLVS 79 >2C4R-L nrPDB Length = 517 Score = 34.8 bits (78), Expect = 0.18, Method: Composition-based stats. Identities = 22/100 (22%), Positives = 44/100 (44%), Gaps = 6/100 (6%) Query: 208 RREPRHLAISNMPLVKSVTVAEGLIEDHFDVTVKMSTYLVAFIISDFESVSKITKSGVKV 267 R+ L++S + L++ + E E H V V +++YL+ S ++ + + GV+ Sbjct: 420 VRDNESLSLSILRLIEEEALKENTQEVHAIVPVPIASYLLNEKRSAVNAI-ETRQDGVRC 478 Query: 268 SVYAVPDKINQADYALDAAVTLLEFYEDYFSIPYPLPKQD 307 V D++ Y + E+ ++ Y LPK Sbjct: 479 -VIVPNDQMETPHYHVLRVRKG----EETPTLSYMLPKLH 513 >4CTH-A nrPDB Length = 709 Score = 34.4 bits (77), Expect = 0.26, Method: Composition-based stats. Identities = 21/105 (20%), Positives = 37/105 (35%), Gaps = 25/105 (23%) Query: 314 FQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVAHELAH---------QWFGNLV 364 F +G ++ F A++S++ + GI M + HE+ H G+LV Sbjct: 514 FPAGILQPP----------FFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLV 563 Query: 365 TMEWWNDLWLNEGFAKFMEFVSVSVTHPELKVGDYFFGKCFDAME 409 W W + + F E V D G+ + + Sbjct: 564 ---DW---WTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGIN 602 >4FGM-A nrPDB Length = 597 Score = 34.0 bits (76), Expect = 0.29, Method: Composition-based stats. Identities = 27/161 (16%), Positives = 45/161 (27%), Gaps = 25/161 (15%) Query: 315 QSGAME--NWGLTTYRESALLFDAEKSSASSKLGITMTVAHELAHQWFGNLVTME----- 367 G +E N L+ + + HE H W N+ T++ Sbjct: 233 GFGGLEHRNSTALLCSRKDLISAHQYEMNDNYQTFLSLCCHEYFHSW--NIKTLKPKAFL 290 Query: 368 --------WWNDLWLNEGFAKFMEFVSVSVTH-PELKVGDYFFGKCFDAMEVDALNSSHP 418 + LW EG + + + + + K G +E A Sbjct: 291 PYQLEKESYTEQLWFYEGMTSYFDDYLLHTSGIIDEKRYLKLLGDTLSRVERGAGQYQQS 350 Query: 419 VSTP-----VENPAQIREMFDDVS--YDKGACILNMLREYL 452 V+ + Q + + Y KGA I L L Sbjct: 351 VTESSFLAWTKFYQQNENAPNSIVSYYAKGALIALSLDLML 391 >2G9B-A nrPDB Length = 263 Score = 33.3 bits (74), Expect = 0.55, Method: Composition-based stats. Identities = 38/244 (15%), Positives = 81/244 (33%), Gaps = 21/244 (8%) Query: 363 LVTMEWWNDLWLNEGFAKFMEFVSVSVTHPELKVGDYFFGKCFDAMEVDALNSSHPVSTP 422 L+T + ++WL+ F + + E K + A + L S + T Sbjct: 12 LITASQFFEIWLH--------FDADGSGYLEGKELQNLIQELLQARKKAGLELSPEMKTF 63 Query: 423 VENPAQ-------IREMFDDVSYDKGACILNMLREYLSADAFKSGIVQYLQKHSYKNTKN 475 V+ Q I E+ + ++ +L ++ S + F +Y HS + Sbjct: 64 VDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSG-FIET 122 Query: 476 EDLWDSMASICPTDGVKGMDGFCSRSQHSSSSSHWHQEG--VDVKTMMNTWTLQKGFPL- 532 E+L + + + D + +++ M +Q+ F L Sbjct: 123 EELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLK 182 Query: 533 -ITITVRGRNVHMKQEHYMKGSDGAPDTGYLWHVPLTFITSKSDMVHRFLLKT-KTDVLI 590 I + G+ + E Y + +G D L + + + T K +++ Sbjct: 183 FQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQELDINNISTYKKNIMA 242 Query: 591 LPEE 594 L + Sbjct: 243 LSDG 246 >6NF9-A nrPDB Length = 576 Score = 32.9 bits (73), Expect = 0.63, Method: Composition-based stats. Identities = 41/191 (21%), Positives = 70/191 (36%), Gaps = 15/191 (7%) Query: 17 LSSLLALLTVSTPSWCQSTEASPKRSDGTPFPWNKIRLPEYVIPVHYD--LLIHANLTTL 74 L++ L ++ + T + T A+P+ +PW LP P HY + NLT Sbjct: 167 LTASL-MVALDTNNTLPYTPAAPRSETLGFYPW----LPT--KPTHYRYYMTCTRNLTPP 219 Query: 75 TFWGTT-KVEITASQPTSTIILHSHHLQISRATLRKGAGERLSEEPLQVLEHPRQEQIAL 133 T G + T S PT + ++ L + G+ S P + + Sbjct: 220 THTGQAGTITNTISAPTHSDVMFYTIENAVPIHLLR-TGDEFSTGTYYFDTKPLKMTHSW 278 Query: 134 LAPEPLLVGLPYTVVIHYAGNLSETFHGFYKSTYRTKEGELRILASTQFEPTAARMAFPC 193 L GLP + + G K+ +EG + + ++ E TA R A Sbjct: 279 QTNRSL--GLPPKLATEPTTE-GQQHTGTLKAA-TDREGIHQTINNSYTEATALRPAQVG 334 Query: 194 FDEPAFKASFS 204 ++ P +S Sbjct: 335 YNTPYMNFEYS 345 >4ARF-A nrPDB Length = 394 Score = 32.5 bits (72), Expect = 0.79, Method: Composition-based stats. Identities = 33/182 (18%), Positives = 52/182 (28%), Gaps = 10/182 (5%) Query: 316 SGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVAHELAHQWFGNLVTMEWW--NDLW 373 G N G F E+ + S + HE H G W L+ Sbjct: 91 YGYDTNNGGMYIEPEGTFFTYEREAQESTYTLEELFRHEYTHYLQGRYAVPGQWGRTKLY 150 Query: 374 LNEGFAKFMEFVSVSVTHPELKVGDYFFGKCFDAMEVDALNSSHPVSTPVENP------- 426 N+ + E + G + N+ + +S V + Sbjct: 151 DNDRLTWYEEGGAELFAGSTRTSGILPRKSIVSNIHNTTRNNRYKLSDTVHSKYGASFEF 210 Query: 427 AQIREMFDDVSYDKGACILNMLREYLSADAFKSGIVQYLQKHSYKNTKNEDLWDSMASIC 486 MF D Y+K ILN L + + G Y++ S + N+ D M Sbjct: 211 YNYACMFMDYMYNKDMGILNKLNDLAKNNDVD-GYDNYIRDLSSNHALNDKYQDHMQERI 269 Query: 487 PT 488 Sbjct: 270 DN 271 >1BQB-A nrPDB Length = 301 Score = 32.5 bits (72), Expect = 0.86, Method: Composition-based stats. Identities = 32/217 (14%), Positives = 69/217 (31%), Gaps = 29/217 (13%) Query: 286 AVTLLEFYEDYFSIP-YPLPKQDLAAIPDFQ-SGAMENWG-LTTYRESALLFDAEKSSAS 342 A ++Y++ F Y + ++ G +N + + D + + + Sbjct: 74 AKQTYDYYKNTFGRESYDNHGSPIVSLTHVNHYGGQDNRNNAAWIGDKMIYGDGDGRTFT 133 Query: 343 SKLGITMTVAHELAHQWFGNLVTMEWWNDL-WLNEGFAKFMEFVSVSVTHPELKVGDYFF 401 + G VAHE+ H +E+ + LNE F+ + D+ Sbjct: 134 NLSGANDVVAHEITHGVTQQTANLEYKDQSGALNESFSDVFGYFVDD--------EDFLM 185 Query: 402 GKCF--DAMEVDALNSSHPVSTPVENPAQIREMFD-----------DVSYDKGACILNML 448 G+ E DAL S + ++ + ++ + Sbjct: 186 GEDVYTPGKEGDALRSMSNPEQFGQPSHMKDYVYTEKDNGGVHTNSGIPNKAAYNVIQAI 245 Query: 449 REYLSADAFKSGIVQYLQKHSYKNTKNEDLWDSMASI 485 + S + + +YL +S +DL D++ Sbjct: 246 GKSKSEQIYYRALTEYLTSNS----NFKDLKDALYQA 278 >1XMD-A nrPDB Length = 612 Score = 32.1 bits (71), Expect = 1.1, Method: Composition-based stats. Identities = 10/62 (16%), Positives = 23/62 (37%), Gaps = 7/62 (11%) Query: 878 TTNQFSTRTRLEEVKGFFSSLKENGSQLRCVQQTIETIEENIGWMDKNFDKIRVWLQSEK 937 + F+ ++ + +E G+ R Q+ +E W+++ WL Sbjct: 38 SVKPFANEDEYKKTEEIVQKFQE-GAGKRLHQKLLERARGKRNWLEE------WWLNVAY 90 Query: 938 LE 939 L+ Sbjct: 91 LD 92 >4B52-A nrPDB Length = 304 Score = 31.3 bits (69), Expect = 2.0, Method: Composition-based stats. Identities = 30/172 (17%), Positives = 61/172 (35%), Gaps = 29/172 (16%) Query: 334 FDAEKSSASSKLGITMTVAHELAH---QWFGNLVTMEWW-NDLWLNEGFAKFMEFVSVSV 389 D + S+ + G V HEL H ++ NL E++ LNE F+ + + + Sbjct: 116 GDGDGSTFIAFSGDPDVVGHELTHGVTEYTSNL---EYYGESGALNEAFS---DVIGNDI 169 Query: 390 THPELKVGDYFFGKCFDAMEVDALNSSHPVSTPVENPAQIREMFDDVSYDKG----ACIL 445 VGD + + ++++ T + P ++ S + G + I+ Sbjct: 170 QRKNWLVGDDIYTPNIAGDALRSMSNP----TLYDQPDHYSNLYTGSSDNGGVHTNSGII 225 Query: 446 NMLREYLSADAFKSG-----------IVQYLQKHSYKNTKNEDLWDSMASIC 486 N L+ G + Y + T + D ++ A++ Sbjct: 226 NKAYYLLAQGGTFHGVTVNGIGRDAAVQIYYSAFTNYLTSSSDFSNARAAVI 277 >3CQB-A nrPDB Length = 107 Score = 30.9 bits (68), Expect = 2.7, Method: Composition-based stats. Identities = 17/62 (27%), Positives = 28/62 (45%), Gaps = 7/62 (11%) Query: 305 KQDLAAIPDFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVAHELAHQWFGNLV 364 D A I F +GA + L + LL + ++ +AHE++H G++V Sbjct: 48 IYDSADINAFATGAKRDDSLVAV-STGLLHN------MTRDEAEAVLAHEVSHIANGDMV 100 Query: 365 TM 366 TM Sbjct: 101 TM 102 >5TON-A nrPDB Length = 414 Score = 29.8 bits (65), Expect = 5.2, Method: Composition-based stats. Identities = 8/15 (53%), Positives = 10/15 (66%) Query: 354 ELAHQWFGNLVTMEW 368 EL H+W GN+ TM Sbjct: 316 ELFHEWTGNVKTMAD 330 >5IMY-A nrPDB Length = 490 Score = 29.8 bits (65), Expect = 6.4, Method: Composition-based stats. Identities = 19/133 (14%), Positives = 41/133 (30%), Gaps = 3/133 (2%) Query: 412 ALNSSHPVSTPVENPAQIREMFDDVSYDKGACILNM---LREYLSADAFKSGIVQYLQKH 468 + S P ++ + D+ YDK + + S+D+F + +H Sbjct: 8 SAKDSEPATSCAAKKDSLNNYLWDLQYDKTNILARHGETIENKFSSDSFNKNGEFVVVEH 67 Query: 469 SYKNTKNEDLWDSMASICPTDGVKGMDGFCSRSQHSSSSSHWHQEGVDVKTMMNTWTLQK 528 KN N S+ S G ++ + S + ++ Sbjct: 68 QKKNITNTTSNLSVTSANDDRVYPGALFRADKNLMDNMPSLISANRAPITLSVDLPGFHG 127 Query: 529 GFPLITITVRGRN 541 G +T+ ++ Sbjct: 128 GESAVTVQRPTKS 140 >1W8I-A nrPDB Length = 156 Score = 29.0 bits (63), Expect = 9.1, Method: Composition-based stats. Identities = 14/67 (20%), Positives = 27/67 (40%), Gaps = 2/67 (2%) Query: 419 VSTPVENPAQIREMFDDVSYDKGACILNMLREYLSADAFKSGIVQYLQKHSYKNTKNEDL 478 + T E + E+F Y+KG + + E ++ + K ++ Y + S D Sbjct: 76 IYTDDEVERKALEVFKARVYEKGFSYTDAISEVVAEE-LKLKLISYDSRFSLPTI-GRDY 133 Query: 479 WDSMASI 485 W S+ Sbjct: 134 WKSLDES 140 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.121 0.316 Lambda K H 0.267 0.0370 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 31,620,477 Number of Sequences: 36641 Number of extensions: 1158553 Number of successful extensions: 3518 Number of sequences better than 10.0: 34 Number of HSP's better than 10.0 without gapping: 38 Number of HSP's successfully gapped in prelim test: 22 Number of HSP's that attempted gapping in prelim test: 3288 Number of HSP's gapped (non-prelim): 74 length of query: 941 length of database: 10,336,785 effective HSP length: 106 effective length of query: 835 effective length of database: 6,452,839 effective search space: 5388120565 effective search space used: 5388120565 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 63 (29.0 bits)