BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9NWU1 (459 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2IWZ-A nrPDB 869 0.0 2IX4-A nrPDB 403 e-113 3KZU-A nrPDB 384 e-107 4JGA-A nrPDB 378 e-105 4LS7-A nrPDB 373 e-104 1J3N-A nrPDB 370 e-102 4QAV-A nrPDB 356 1e-98 3O04-A nrPDB 354 4e-98 4JRH-A nrPDB 354 4e-98 2GQD-A nrPDB 349 2e-96 4R8E-A nrPDB 347 9e-96 4JPF-A nrPDB 346 1e-95 3E60-A nrPDB 345 2e-95 1E5M-A nrPDB 345 2e-95 4DDO-A nrPDB 322 2e-88 3HO9-A nrPDB 322 2e-88 1OXH-A nrPDB 261 3e-70 4XOX-A nrPDB 228 3e-60 2GP6-A nrPDB 223 2e-58 1TQY-A nrPDB 216 1e-56 3U0E-A nrPDB 215 2e-56 5W2O-A nrPDB 214 6e-56 3OYT-A nrPDB 214 6e-56 2BZ4-A nrPDB 206 2e-53 6QSP-A nrPDB 140 1e-33 1TQY-B nrPDB 122 3e-28 4OQJ-A nrPDB 106 2e-23 5ENY-A nrPDB 97 1e-20 4CW4-A nrPDB 65 5e-11 4E1L-A nrPDB 42 7e-04 4N44-A nrPDB 35 0.062 5ZQZ-B nrPDB 34 0.12 4DD5-A nrPDB 33 0.31 5LP7-H nrPDB 31 0.98 6ARG-A nrPDB 30 1.9 2IBU-A nrPDB 30 2.5 3SS6-A nrPDB 29 4.6 6BN2-A nrPDB 29 4.7 1NL7-A nrPDB 29 5.0 6FKX-A nrPDB 28 6.9 4FFM-A nrPDB 28 7.0 4C2K-A nrPDB 28 7.8 >2IWZ-A nrPDB Length = 438 Score = 869 bits (2245), Expect = 0.0, Method: Compositional matrix adjust. Identities = 422/422 (100%), Positives = 422/422 (100%) Query: 38 SRLHRRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSD 97 SRLHRRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSD Sbjct: 17 SRLHRRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSD 76 Query: 98 EGQFNEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPL 157 EGQFNEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPL Sbjct: 77 EGQFNEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPL 136 Query: 158 EVVSETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVG 217 EVVSETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVG Sbjct: 137 EVVSETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVG 196 Query: 218 DSFRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALSTNSDPKLACRPFHPKRDGFVMG 277 DSFRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALSTNSDPKLACRPFHPKRDGFVMG Sbjct: 197 DSFRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALSTNSDPKLACRPFHPKRDGFVMG 256 Query: 278 EGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGV 337 EGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGV Sbjct: 257 EGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGV 316 Query: 338 QPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAF 397 QPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAF Sbjct: 317 QPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAF 376 Query: 398 TTLACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCIA 457 TTLACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCIA Sbjct: 377 TTLACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCIA 436 Query: 458 GL 459 GL Sbjct: 437 GL 438 >2IX4-A nrPDB Length = 431 Score = 403 bits (1036), Expect = e-113, Method: Compositional matrix adjust. Identities = 224/439 (51%), Positives = 299/439 (68%), Gaps = 29/439 (6%) Query: 42 RRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYK--------------SIPCS 87 RRVV+TG+G+VTPLG G W RLI GE GI L ++ K + Sbjct: 1 RRVVVTGLGMVTPLGRGVETTWRRLIDGECGIRGLTLDDLKMKSFDEETKLYTFDQLSSK 60 Query: 88 VAAYVPRGSDEGQFNEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATG 147 VAA+VP GS+ G+F+E +++ K++++ A+ AA+ A++D+ W P E ++ TG Sbjct: 61 VAAFVPYGSNPGEFDEALWLNS---KAVANFIGYAVCAADEALRDAEWLPTEEEEKERTG 117 Query: 148 VAIGMGMIPLEVVSETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVST 207 V+IG G+ + + E A K ++SPFF+PKILVNMA+G VS++Y +GPNHA T Sbjct: 118 VSIGGGIGSICDIVEAAQLICEKRLRRLSPFFIPKILVNMASGHVSMKYGFQGPNHAAVT 177 Query: 208 ACTTGAHAVGDSFRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALST--NSDPKLACR 265 AC TGAH++GD+ R I GDADVMVAGGT+S I LS+AGFSR+RALST NS P+ A R Sbjct: 178 ACATGAHSIGDATRMIQFGDADVMVAGGTESSIDALSVAGFSRSRALSTKFNSSPQEASR 237 Query: 266 PFHPKRDGFVMGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGAL 325 PF RDGFV+GEG+ V+VLEEYEHA +R A+IYAE+ GYG+SGDA HIT P +G+GA+ Sbjct: 238 PFDCDRDGFVIGEGSGVIVLEEYEHAKRRGAKIYAELCGYGMSGDAHHITQPPEDGKGAV 297 Query: 326 RCMAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYA--LAVSSTKGAT 383 M AL+ +G+ P +I Y+NAHATSTP+GDA E +AIK +F +HA + LA SSTKGAT Sbjct: 298 LAMTRALRQSGLCPNQIDYVNAHATSTPIGDAVEARAIKTVFSEHATSGTLAFSSTKGAT 357 Query: 384 GHLLGAAGAVEAAFTTLACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFI---G 440 GHLLGAAGAVEA F+ LA ++ P TLN+ +P FD ++PL T K+ + Sbjct: 358 GHLLGAAGAVEAIFSILAIHHGVAPMTLNVKNPDPIFDKRFMPL-----TTSKKMLVRTA 412 Query: 441 LTNSFGFGGTNATLCIAGL 459 ++NSFGFGGTNA+L A + Sbjct: 413 MSNSFGFGGTNASLLFASI 431 >3KZU-A nrPDB Length = 428 Score = 384 bits (987), Expect = e-107, Method: Compositional matrix adjust. Identities = 216/418 (51%), Positives = 284/418 (67%), Gaps = 7/418 (1%) Query: 42 RRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGS-DEGQ 100 RRVVITG+GLV+PL G W RL+ GESG + E + C +A +P G G Sbjct: 10 RRVVITGLGLVSPLASGVEETWKRLLAGESGARRVTEFEVDDLACQIACRIPVGDGTNGT 69 Query: 101 FNEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVV 160 FN + + + + + A+GAA+ A+ D+GWHP+++ DQV TGV IG G+ +E + Sbjct: 70 FNPDLHMDPKEQRKVDPFIVYAVGAADQALDDAGWHPENDEDQVRTGVLIGSGIGGIEGI 129 Query: 161 SETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSF 220 E + KG ++SPFF+P L+N+A+G VSI++KL+GPNH+V TAC TG HA+GD+ Sbjct: 130 VEAGYTLRDKGPRRISPFFIPGRLINLASGHVSIKHKLRGPNHSVVTACATGTHAIGDAA 189 Query: 221 RFIAHGDADVMVAGGTDSCISPLSLAGFSRARALST--NSDPKLACRPFHPKRDGFVMGE 278 R IA GDADVMVAGGT+S +S +SLAGF+ +ALST N DP A RP+ RDGFVMGE Sbjct: 190 RLIAFGDADVMVAGGTESPVSRISLAGFAACKALSTERNDDPTAASRPYDEDRDGFVMGE 249 Query: 279 GAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGVQ 338 GA ++VLEE EHA+ R A+IYAEV+GYG+SGDA HITAP GEGA RCM AALK AG+ Sbjct: 250 GAGIVVLEELEHALARGAKIYAEVIGYGMSGDAFHITAPTESGEGAQRCMVAALKRAGIV 309 Query: 339 PEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFT 398 P+EI YINAH TST + D E A++ + + A +++SSTK + GHLLGAAGA EA F+ Sbjct: 310 PDEIDYINAHGTST-MADTIELGAVERVVGEAAAKISMSSTKSSIGHLLGAAGAAEAVFS 368 Query: 399 TLACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCI 456 TLA P TLNLD + ++ VP K +E K + + L+NSFGFGGTNA+L + Sbjct: 369 TLAIRDNIAPATLNLDNPAAQTRIDLVPHKPRERKID---VALSNSFGFGGTNASLVL 423 >4JGA-A nrPDB Length = 437 Score = 378 bits (971), Expect = e-105, Method: Compositional matrix adjust. Identities = 200/426 (46%), Positives = 277/426 (65%), Gaps = 9/426 (2%) Query: 39 RLHRRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDE 98 R+++RVVITG+GLVTP+G+ + W ++ G SGI ++ + + C +A + + Sbjct: 13 RVNKRVVITGLGLVTPVGLNVNSSWKNIVDGVSGIKTITEFDTSKLACKIAGLIDNSEKD 72 Query: 99 GQFNEQNFVSKSDIKSMSSPTIM---AIGAAELAMKDSGWHPQSEADQVATGVAIGMGMI 155 G F +NF DI +S + AA A++DSGW P E + TG+ +G G+ Sbjct: 73 G-FKLENFTQADDINRLSKMDKFIHYGVAAATEAVEDSGWLPDDEKSRDRTGLILGSGIG 131 Query: 156 PLEVVSETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHA 215 L+++ +T++ + KVSPFF+P L+N+ +G VSI+Y GPN TAC+TGAHA Sbjct: 132 GLKMIEDTSIKLYQENNGKVSPFFIPASLINLLSGLVSIKYGFSGPNQTAVTACSTGAHA 191 Query: 216 VGDSFRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALST--NSDPKLACRPFHPKRDG 273 +GD+ R I HG ADVM+AGG ++ ++P+ +AGF ARAL T N +PK A RP+ R G Sbjct: 192 IGDAMRMIKHGYADVMIAGGAEAPVTPVGVAGFVAARALCTKYNDNPKKASRPWDKDRSG 251 Query: 274 FVMGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALK 333 FVMGEGA V+VLEEYEHA+ R A++Y EV+GYG +GDA H+TAP PEG GA R M A+ Sbjct: 252 FVMGEGAGVVVLEEYEHALNRGAKVYGEVIGYGSTGDAYHMTAPHPEGRGAYRAMRDAML 311 Query: 334 DAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAV 393 DA + P+ I YINAH TST LGD E A++ LF + + +SSTK + GHLLGAAG+V Sbjct: 312 DATITPDMIDYINAHGTSTTLGDGIELAAVQKLFLEANPKVLMSSTKSSIGHLLGAAGSV 371 Query: 394 EAAFTTLACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNAT 453 E F+ LA Q PPTLNLD E +++ V LKA+ KT+ ++ L+NSFGFGGTNA+ Sbjct: 372 EFIFSALAIRDQIAPPTLNLDTPMDEVNIDLVALKAK--KTKIDYV-LSNSFGFGGTNAS 428 Query: 454 LCIAGL 459 L I + Sbjct: 429 LVIKSI 434 >4LS7-A nrPDB Length = 426 Score = 373 bits (958), Expect = e-104, Method: Compositional matrix adjust. Identities = 201/421 (47%), Positives = 271/421 (64%), Gaps = 14/421 (3%) Query: 37 ISRLHRRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGS 96 I +RVV+TG+G ++PLG W+ I G SGI + + + P VAA + Sbjct: 12 IQMTKKRVVVTGLGALSPLGNDVDTSWNNAINGVSGIGPITRVDAEEYPAKVAAELK--- 68 Query: 97 DEGQFNEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVA--TGVAIGMGM 154 FN ++++ K + + M T A+ AA++A++D+ + D++A GV +G G+ Sbjct: 69 ---DFNVEDYMDKKEARKMDRFTQYAVVAAKMAVEDADLNI---TDEIAPRVGVWVGSGI 122 Query: 155 IPLEVVSETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAH 214 LE + F TKG +VSPFFVP ++ +MA GQ+SI KG N TAC TG + Sbjct: 123 GGLETLESQFEIFLTKGPRRVSPFFVPMMIPDMATGQISIALGAKGVNSCTVTACATGTN 182 Query: 215 AVGDSFRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALSTNSDPKLACRPFHPKRDGF 274 ++GD+F+ I GDADVMV GGT++ ++ +S AGFS +ALSTN DPK A RPF RDGF Sbjct: 183 SIGDAFKVIQRGDADVMVTGGTEAPLTRMSFAGFSANKALSTNPDPKTASRPFDKNRDGF 242 Query: 275 VMGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKD 334 VMGEGA ++VLEE EHA+ R A+IY E++GYG +GDA HITAP +GEG R M A+KD Sbjct: 243 VMGEGAGIIVLEELEHALARGAKIYGEIVGYGSTGDAYHITAPAQDGEGGARAMQEAIKD 302 Query: 335 AGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVE 394 AG+ PEEI YINAH TST D E AIK +F +HA+ LAVSSTK TGHLLGAAG +E Sbjct: 303 AGIAPEEIDYINAHGTSTYYNDKYETMAIKTVFGEHAHKLAVSSTKSMTGHLLGAAGGIE 362 Query: 395 AAFTTLACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATL 454 A F+ LA +PPT+N+ + E DL+YVP +A+ + E ++ L+NS GFGG NATL Sbjct: 363 AIFSILAIKEGVIPPTINIQTPDEECDLDYVPDEAR--RQELNYV-LSNSLGFGGHNATL 419 Query: 455 C 455 Sbjct: 420 I 420 >1J3N-A nrPDB Length = 408 Score = 370 bits (949), Expect = e-102, Method: Compositional matrix adjust. Identities = 193/416 (46%), Positives = 269/416 (64%), Gaps = 13/416 (3%) Query: 42 RRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDEGQF 101 RRVV+TG+G +TP+GVG + G+SG+ + + ++P +AA V Sbjct: 2 RRVVVTGLGALTPIGVGQEAFHKAQLAGKSGVRPITRFDASALPVRIAAEV-------DV 54 Query: 102 NEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVVS 161 + ++ + +++ + A+ AA+LA++D+G P+ + D G +G G+ +E Sbjct: 55 DPGAYLDRKELRRLDRFVQYALIAAQLALEDAGLKPE-DLDPERVGTLVGTGIGGMETWE 113 Query: 162 ETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSFR 221 + F +G N++SPFF+P ++ NMA+ +++RY GP+ V TAC TGA A+G + R Sbjct: 114 AQSRVFLERGPNRISPFFIPMMIANMASAHIAMRYGFTGPSSTVVTACATGADALGSALR 173 Query: 222 FIAHGDADVMVAGGTDSCISPLSLAGFSRARALST-NSDPKLACRPFHPKRDGFVMGEGA 280 I G+AD+++AGGT++ I+P+++ F+ RALST N +P+ A RPF RDGFVMGEGA Sbjct: 174 MIQLGEADLVLAGGTEAAITPMAIGAFAVMRALSTRNEEPEKASRPFTLSRDGFVMGEGA 233 Query: 281 AVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGVQPE 340 VLVLE YEHA +R ARIYAE++G+G S DA HIT P PEG+GA MA ALKDAG+ PE Sbjct: 234 GVLVLEAYEHAKKRGARIYAELVGFGRSADAHHITEPHPEGKGAALAMARALKDAGIAPE 293 Query: 341 EISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFTTL 400 ++ YINAH TSTP+GD AE AIK +F DHA L VSSTK GHLLGAAGAVEA T Sbjct: 294 QVGYINAHGTSTPVGDRAEVLAIKRVFGDHAKRLMVSSTKSMIGHLLGAAGAVEAIATVQ 353 Query: 401 ACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCI 456 A Y+ +PPT+NL+ +PE DL++VP E + K L+NSF FGG NA L Sbjct: 354 ALYHGVIPPTINLEDPDPELDLDFVP----EPREAKVDYALSNSFAFGGHNAVLAF 405 >4QAV-A nrPDB Length = 415 Score = 356 bits (913), Expect = 1e-98, Method: Compositional matrix adjust. Identities = 198/418 (47%), Positives = 267/418 (63%), Gaps = 14/418 (3%) Query: 41 HRRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDEGQ 100 RRVVITG+G V+P+G WD L+ G+SGI ++ + I VA V RG D GQ Sbjct: 3 QRRVVITGLGQVSPVGNTVAEAWDTLLAGKSGIGAITRFDASDINSRVAGEV-RGFDIGQ 61 Query: 101 FNEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVV 160 + +S + + M I AA A+ DSG D+ GV IG G+ L + Sbjct: 62 Y-----ISAKEARRMDVFIHYGIAAALQAIADSGLDDVENLDKDRIGVNIGSGIGGLPSI 116 Query: 161 SETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSF 220 T G K++PFF+P L+N+ +G V+I +GP++ + +ACTTGAHA+G+S Sbjct: 117 EVTGKAVIEGGARKINPFFIPGSLINLISGHVTILKGYRGPSYGMVSACTTGAHAIGNSA 176 Query: 221 RFIAHGDADVMVAGGTDSCISPLSLAGFSRARALST-NSDPKLACRPFHPKRDGFVMGEG 279 R I +GDAD+MVAGG + IS L + GF+ +ALST N DP A RP+ RDGFV+GEG Sbjct: 177 RLIKYGDADIMVAGGAEGAISTLGVGGFAAMKALSTRNDDPATASRPWDKGRDGFVIGEG 236 Query: 280 AAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGVQP 339 A +LVLEE EHA +R A+IYAE++G+G+S DA HITAP+ EG AL + ALKDAG+ P Sbjct: 237 AGILVLEELEHAKKRGAKIYAEIVGFGMSSDAYHITAPNEEGP-AL-AVTRALKDAGINP 294 Query: 340 EEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFTT 399 E++ Y+NAH TSTPLGDA E KA+K F +HAY VSSTK TGHLLGAAG VEA ++ Sbjct: 295 EDVDYVNAHGTSTPLGDANETKALKRAFGEHAYKTVVSSTKSMTGHLLGAAGGVEAVYSI 354 Query: 400 LACYYQKLPPTLNLDCSEPEF--DLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLC 455 LA + K+PPT+N+ + E DL+Y +A++ + + + ++NSFGFGGTN TL Sbjct: 355 LAIHDGKIPPTINIFEQDVEAGCDLDYCANEARDAEID---VAISNSFGFGGTNGTLV 409 >3O04-A nrPDB Length = 413 Score = 354 bits (909), Expect = 4e-98, Method: Compositional matrix adjust. Identities = 189/415 (45%), Positives = 262/415 (63%), Gaps = 12/415 (2%) Query: 42 RRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDEGQF 101 RRVV+TGIG VTP+G W+ G +G+ + P +AA + F Sbjct: 4 RRVVVTGIGAVTPIGNDAETSWENAKKGVNGVAKMTRLNPDDFPVKIAAELK------DF 57 Query: 102 NEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWH-PQSEADQVATGVAIGMGMIPLEVV 160 + + ++ K + + M T AI +AE+A++DSG S A++V GV IG G+ +E Sbjct: 58 DVEKYLEKKEARKMDRFTHYAIASAEMAVQDSGLVIDDSNANRV--GVWIGSGIGGMETF 115 Query: 161 SETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSF 220 F +G+ +VSPFFVP ++ +M +GQVSIR+ KG N TAC T +++GD+F Sbjct: 116 ETQYEIFLNRGHRRVSPFFVPMMIPDMGSGQVSIRFGAKGINSTTVTACATATNSIGDAF 175 Query: 221 RFIAHGDADVMVAGGTDSCISPLSLAGFSRARALSTNSDPKLACRPFHPKRDGFVMGEGA 280 + I GDAD M+ GG ++ I+ +SLAGF+ +ALS N DP+ ACRPF RDGF++GEGA Sbjct: 176 KVIERGDADAMITGGAEAPITKMSLAGFTANKALSLNPDPETACRPFDKDRDGFIIGEGA 235 Query: 281 AVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGVQPE 340 +++LEEYEHA R A+IYAE++GYG +GDA HITAP P GEGA R M A+ DAG+ P+ Sbjct: 236 GIVILEEYEHAKARGAKIYAEIVGYGATGDAYHITAPAPNGEGAARAMKMAIDDAGLTPD 295 Query: 341 EISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFTTL 400 ++ YINAH TSTP D E +AIK +F +HA LA+SSTK TGH LGA+G +EA F L Sbjct: 296 KVDYINAHGTSTPYNDEYETQAIKTVFGEHAKKLAISSTKSMTGHTLGASGGIEAIFALL 355 Query: 401 ACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLC 455 + PT++L + DL+YVP +A+E + ++NSFGFGG NATL Sbjct: 356 TIRDNIIAPTIHLKNQDEVCDLDYVPNEAREANVN---VVISNSFGFGGHNATLV 407 >4JRH-A nrPDB Length = 417 Score = 354 bits (909), Expect = 4e-98, Method: Compositional matrix adjust. Identities = 196/416 (47%), Positives = 260/416 (62%), Gaps = 11/416 (2%) Query: 42 RRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDEGQF 101 RRVV+TG+G+++P+G W L+ G+SGIV++ + + A V F Sbjct: 7 RRVVVTGMGMLSPVGNTVESSWKALLAGQSGIVNIEHFDTTNFSTRFAGLVK------GF 60 Query: 102 NEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVVS 161 + + ++SK D + M I A A++DSG E + GVAIG G+ LE++ Sbjct: 61 DCEQYMSKKDARKMDLFIQYGIAAGIQALEDSGLEVNEE-NAARIGVAIGSGIGGLELIE 119 Query: 162 ETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSFR 221 KG KVSPFFVP +VNM AG +SI L+GPN A+STACTTG H +G + R Sbjct: 120 TGHQALIEKGPRKVSPFFVPSTIVNMIAGNLSIMRGLRGPNIAISTACTTGLHNIGHAAR 179 Query: 222 FIAHGDADVMVAGGTDSCISPLSLAGFSRARALST-NSDPKLACRPFHPKRDGFVMGEGA 280 IA+GDAD MVAGG + +PL +AGF A+ALST N +P+ A RP+ RDGFV+G+GA Sbjct: 180 MIAYGDADAMVAGGAEKASTPLGMAGFGAAKALSTRNDEPQKASRPWDKDRDGFVLGDGA 239 Query: 281 AVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGVQPE 340 ++VLEEYEHA R A+IYAEV+G+G+SGDA H+T+P +G G M AA++DAGV E Sbjct: 240 GIMVLEEYEHAKARGAKIYAEVVGFGMSGDAYHMTSPSEDGSGGALAMEAAMRDAGVTGE 299 Query: 341 EISYINAHATSTPLGDAAENKAIKH-LFKDHAYALAVSSTKGATGHLLGAAGAVEAAFTT 399 +I Y+NAH TSTP GD AE K IK L + + VSSTK TGHLLGAAG+VEA T Sbjct: 300 QIGYVNAHGTSTPAGDVAEVKGIKRALGEAGTKQVLVSSTKSMTGHLLGAAGSVEAIITV 359 Query: 400 LACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLC 455 ++ Q +PPT+NLD E ++ VP A+ K E + NSFGFGGTN +L Sbjct: 360 MSLVDQMVPPTINLDNPEEGLGVDLVPHVAR--KVESMEYAMCNSFGFGGTNGSLI 413 >2GQD-A nrPDB Length = 437 Score = 349 bits (895), Expect = 2e-96, Method: Compositional matrix adjust. Identities = 187/416 (44%), Positives = 261/416 (62%), Gaps = 12/416 (2%) Query: 41 HRRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDEGQ 100 ++RVVITG+G ++P+G W+ + G +GI + + + +A + Sbjct: 27 NKRVVITGMGALSPIGNDVKTTWENALKGVNGIDKITRIDTEPYSVHLAGELK------N 80 Query: 101 FNEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWH-PQSEADQVATGVAIGMGMIPLEV 159 FN ++ + K + + M T AI AA A+KD+ ++ AD++ GV IG G+ +E Sbjct: 81 FNIEDHIDKKEARRMDRFTQYAIVAAREAVKDAQLDINENTADRI--GVWIGSGIGGMET 138 Query: 160 VSETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDS 219 KG +VSPFFVP ++ +MA GQVSI KGPN A TAC TG +++G++ Sbjct: 139 FEIAHKQLMDKGPRRVSPFFVPMLIPDMATGQVSIDLGAKGPNGATVTACATGTNSIGEA 198 Query: 220 FRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALSTNSDPKLACRPFHPKRDGFVMGEG 279 F+ + GDAD M+ GGT++ I+ +++AGFS +RALSTN D + ACRPF RDGFVMGEG Sbjct: 199 FKIVQRGDADAMITGGTEAPITHMAIAGFSASRALSTNDDIETACRPFQEGRDGFVMGEG 258 Query: 280 AAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGVQP 339 A +LV+E E A R A IYAE++GYG +GDA HITAP PEGEG R M AA+ DAG++P Sbjct: 259 AGILVIESLESAQARGANIYAEIVGYGTTGDAYHITAPAPEGEGGSRAMQAAMDDAGIEP 318 Query: 340 EEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFTT 399 +++ Y+NAH TSTP+GD E KAIK+ F + A L VSSTK TGHLLGA G +EA F+ Sbjct: 319 KDVQYLNAHGTSTPVGDLNEVKAIKNTFGEAAKHLKVSSTKSMTGHLLGATGGIEAIFSA 378 Query: 400 LACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLC 455 L+ K+ PT++ +PE DL+ VP +AQ+ ++NS GFGG NA L Sbjct: 379 LSIKDSKVAPTIHAVTPDPECDLDIVPNEAQDLDIT---YAMSNSLGFGGHNAVLV 431 >4R8E-A nrPDB Length = 413 Score = 347 bits (889), Expect = 9e-96, Method: Compositional matrix adjust. Identities = 191/416 (45%), Positives = 266/416 (63%), Gaps = 10/416 (2%) Query: 42 RRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDEGQF 101 RRVV+TG+G+++P+G W ++ G+SGI + + + A V F Sbjct: 4 RRVVVTGLGMLSPVGNTVESTWKAVLAGQSGISLIDHFDTSAYATRFAGLVK------DF 57 Query: 102 NEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVVS 161 N ++++S+ D + M + + A AM+D+G +EA+ G AIG G+ L ++ Sbjct: 58 NCEDYISRKDARKMDAFIQYGVAAGMQAMQDAGLDI-TEANASRIGAAIGSGIGGLGLIE 116 Query: 162 ETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSFR 221 E G K+SPFFVP +VNM AG ++I Y L+GP+ +++TACT+G H +G + R Sbjct: 117 ENHTALVNGGPRKISPFFVPSTIVNMIAGHLTIMYGLRGPSISIATACTSGVHNIGHAAR 176 Query: 222 FIAHGDADVMVAGGTDSCISPLSLAGFSRARALST-NSDPKLACRPFHPKRDGFVMGEGA 280 IA+ DADVMVAGG + +PL + GF ARALST N +P+ A RP+ RDGFV+G+GA Sbjct: 177 IIAYNDADVMVAGGAEKASTPLGVGGFGAARALSTRNDNPQAASRPWDKDRDGFVLGDGA 236 Query: 281 AVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGVQPE 340 ++VLEEYEHA +R A+IYAEV+G+G+S DA H+T+P +G GA M AL+DAG+ Sbjct: 237 GMMVLEEYEHAKKRGAKIYAEVVGFGMSSDAYHMTSPPEDGSGAALAMVNALRDAGITTS 296 Query: 341 EISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFTTL 400 +I YINAH TSTP GD AE +A+K +F + AY + VSSTK TGHLLGAAGAVE+ FT L Sbjct: 297 QIGYINAHGTSTPAGDKAETQAVKSVFGEDAYKVMVSSTKSMTGHLLGAAGAVESIFTVL 356 Query: 401 ACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCI 456 A Q +P T+NLD + DL+YVP A++ K + L NSFGFGGTN +L Sbjct: 357 ALRDQAIPATINLDNPDEGCDLDYVPHDARQVKDME--YTLCNSFGFGGTNGSLVF 410 >4JPF-A nrPDB Length = 436 Score = 346 bits (888), Expect = 1e-95, Method: Compositional matrix adjust. Identities = 198/419 (47%), Positives = 275/419 (65%), Gaps = 15/419 (3%) Query: 41 HRRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPR--GSDE 98 RRVVITG+G+++PLG+ W+ ++ G SGI + E+ + +AY R GS + Sbjct: 25 RRRVVITGMGMLSPLGLDVPSSWEGILAGRSGIAPI---EHMDL----SAYSTRFGGSVK 77 Query: 99 GQFNEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLE 158 G FN + ++S + + + + A+ A++DSG ++A++ GV++G G+ L Sbjct: 78 G-FNVEEYLSAKEARKLDLFIQYGLAASFQAVRDSGLE-VTDANRERIGVSMGSGIGGLT 135 Query: 159 VVSETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGD 218 + + +G ++SPFFVP ++NM +G +SI L+GPN+A++TACTTG H++G Sbjct: 136 NIENNCRSLFEQGPRRISPFFVPGSIINMVSGFLSIHLGLQGPNYALTTACTTGTHSIGM 195 Query: 219 SFRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALST-NSDPKLACRPFHPKRDGFVMG 277 + R IA+G+ADVMVAGG++ L L GF ARALST N +P A RP+ RDGFV+ Sbjct: 196 AARNIAYGEADVMVAGGSEMAACGLGLGGFGAARALSTRNDEPTRASRPWDRDRDGFVLS 255 Query: 278 EGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGV 337 +G+ LVLEE EHA R ARIYAE++G+G+SGDA H+TAP +G GA RCM AL+DAG+ Sbjct: 256 DGSGALVLEELEHARARGARIYAELVGFGMSGDAFHMTAPPEDGAGAARCMKNALRDAGL 315 Query: 338 QPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAF 397 P ++ YINAH TSTP GD AE A+K +F +HA+AL++SSTK TGHLLGAAGAVEA F Sbjct: 316 DPRQVDYINAHGTSTPAGDIAEIAAVKSVFGEHAHALSMSSTKSMTGHLLGAAGAVEAIF 375 Query: 398 TTLACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCI 456 + LA Q PPT+NLD + DL+ V A E K K + L+NSFGFGGTN TL Sbjct: 376 SVLALRDQVAPPTINLDNPDEGCDLDLV---AHEAKPRKIDVALSNSFGFGGTNGTLVF 431 >3E60-A nrPDB Length = 424 Score = 345 bits (886), Expect = 2e-95, Method: Compositional matrix adjust. Identities = 211/418 (50%), Positives = 279/418 (66%), Gaps = 7/418 (1%) Query: 42 RRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGS-DEGQ 100 RRVVITG+GLV+PL W RL+ G+SG+ + + + C +AA +P G G Sbjct: 6 RRVVITGLGLVSPLAGDVEYSWKRLLEGKSGVRRITEFDVSDLSCQIAARIPVGDGTNGT 65 Query: 101 FNEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVV 160 +N + + + + + + AI AA+ A+ D+ W P+S+ DQ+ TGV IG G+ +E + Sbjct: 66 YNADLHMESKEQRKVDAFIVYAIAAADQALADAEWFPKSDEDQICTGVLIGSGIGGIEGI 125 Query: 161 SETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSF 220 E + KG ++SPFF+P L+N+A+G VSI+Y L+GPNH+V TAC+TGAHA+GD+ Sbjct: 126 VEAGYTLRDKGPRRISPFFIPGRLINLASGYVSIKYGLRGPNHSVVTACSTGAHAIGDAA 185 Query: 221 RFIAHGDADVMVAGGTDSCISPLSLAGFSRARALST--NSDPKLACRPFHPKRDGFVMGE 278 R IA GDADVM+AGGT+S I+ +SLAGFS RALST N DP+ A RP+ RDGFVMGE Sbjct: 186 RLIALGDADVMLAGGTESPINRISLAGFSACRALSTCRNDDPERASRPYDVDRDGFVMGE 245 Query: 279 GAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGVQ 338 GAA++VLEE EHA +R ARIYAE++GYGLSGDA HITAP GEGA R M AALK A V Sbjct: 246 GAAIVVLEELEHAKKRGARIYAEIIGYGLSGDAYHITAPSESGEGAQRSMMAALKRAQVN 305 Query: 339 PEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFT 398 E+ YINAH TST + D E A++ + +A +++SSTK + GHLLGAAGA EA F Sbjct: 306 VSELDYINAHGTST-MADVIELAAVERVLGYYAPQVSMSSTKSSIGHLLGAAGAAEAIFC 364 Query: 399 TLACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCI 456 LA P TLNL+ E ++ VP K +E K + L+NSFGFGGTNA+L + Sbjct: 365 VLAIRDNIAPATLNLENPSIETKIDLVPHKPRERKIDTV---LSNSFGFGGTNASLVM 419 >1E5M-A nrPDB Length = 416 Score = 345 bits (885), Expect = 2e-95, Method: Compositional matrix adjust. Identities = 183/415 (44%), Positives = 260/415 (62%), Gaps = 13/415 (3%) Query: 42 RRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDEGQF 101 +RVV+TG+G +TP+G W L+ G +GI + + C G + F Sbjct: 7 KRVVVTGLGAITPIGNTLQDYWQGLMEGRNGIGPITRFDASDQACRF------GGEVKDF 60 Query: 102 NEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWH-PQSEADQVATGVAIGMGMIPLEVV 160 + F+ + + K M A+ A++ A+ D+ + AD++ GV IG G+ L+V+ Sbjct: 61 DATQFLDRKEAKRMDRFCHFAVCASQQAINDAKLVINELNADEI--GVLIGTGIGGLKVL 118 Query: 161 SETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSF 220 + KG ++ SPF +P ++ NMA+G +I KGPN+ TAC G++A+GD+F Sbjct: 119 EDQQTILLDKGPSRCSPFMIPMMIANMASGLTAINLGAKGPNNCTVTACAAGSNAIGDAF 178 Query: 221 RFIAHGDADVMVAGGTDSCISPLSLAGFSRARALS-TNSDPKLACRPFHPKRDGFVMGEG 279 R + +G A M+ GGT++ I+PLS AGF+ ARALS N DP A RPF RDGFVMGEG Sbjct: 179 RLVQNGYAKAMICGGTEAAITPLSYAGFASARALSFRNDDPLHASRPFDKDRDGFVMGEG 238 Query: 280 AAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGVQP 339 + +L+LEE E A+ R A+IY E++GY ++ DA HITAP P+G GA R +A ALKD+G++P Sbjct: 239 SGILILEELESALARGAKIYGEMVGYAMTCDAYHITAPVPDGRGATRAIAWALKDSGLKP 298 Query: 340 EEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFTT 399 E +SYINAH TSTP D E +AIK +HAY +AVSSTK TGHLLG +G +EA T Sbjct: 299 EMVSYINAHGTSTPANDVTETRAIKQALGNHAYNIAVSSTKSMTGHLLGGSGGIEAVATV 358 Query: 400 LACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATL 454 +A K+PPT+NL+ +PE DL+YVP +++ + + L+NSFGFGG N TL Sbjct: 359 MAIAEDKVPPTINLENPDPECDLDYVPGQSRALIVD---VALSNSFGFGGHNVTL 410 >4DDO-A nrPDB Length = 451 Score = 322 bits (826), Expect = 2e-88, Method: Compositional matrix adjust. Identities = 191/419 (45%), Positives = 268/419 (63%), Gaps = 13/419 (3%) Query: 43 RVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSD--EGQ 100 RVV+TGIG+V+PLG G LVW RLIGG SG+ L + + V V ++ EG Sbjct: 25 RVVVTGIGIVSPLGCGKELVWQRLIGGGSGLRRLGDDIAGELSAKVGGTVQDVAEDPEGG 84 Query: 101 FNEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEA--DQVATGVAIGMGMIPLE 158 F+ + V +++ M MA+ AA+ A+ ++GW P++E ++ AT VA G+G P Sbjct: 85 FDPERSVPHKELRKMDRFIQMAMVAADEALAEAGWAPEAEQQRERTATVVASGIGGFP-- 142 Query: 159 VVSETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGD 218 ++E +T+G ++SPF +P L N+AAGQ+SI+++ +GP TAC A+GD Sbjct: 143 GLAEAVRIGETRGVRRLSPFTIPFFLSNLAAGQISIKHRFRGPLGCPVTACAASVQAIGD 202 Query: 219 SFRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALST--NSDPKLACRPFHPKRDGFVM 276 + R I G+ADV++AGG ++ +SL GF+ ARALST + +P A RPF RDGFVM Sbjct: 203 AMRMIRTGEADVVLAGGAEAAFDKVSLGGFAAARALSTGFSEEPVRASRPFDRDRDGFVM 262 Query: 277 GEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAG 336 GEGAA++V+E +HA+ R AR AE++GYG + DA H+TA +G GA+R M AL+ Sbjct: 263 GEGAAMVVVESLDHALARGARPIAEIIGYGTTADAYHMTAGPDDGSGAMRAMKLALRMGD 322 Query: 337 VQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAA 396 V PE++ Y+NAHATSTP+GDA E +A+K +F A A+SSTK ATGHLLGAAGA+EAA Sbjct: 323 VAPEQVDYVNAHATSTPVGDAGEIEALKTVFGVGA-GPAISSTKSATGHLLGAAGAIEAA 381 Query: 397 FTTLACYYQKLPPTLNLDCSEPEFD-LNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATL 454 F+ LA LP TLNL+ +P D L+ + A+ E I L+N FGFGG NA++ Sbjct: 382 FSILALRDGVLPGTLNLEHPDPAADGLDLIGPAARHVPVE---IALSNGFGFGGVNASV 437 >3HO9-A nrPDB Length = 427 Score = 322 bits (825), Expect = 2e-88, Method: Compositional matrix adjust. Identities = 188/414 (45%), Positives = 267/414 (64%), Gaps = 10/414 (2%) Query: 42 RRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDEGQF 101 RRVV+TG+G+++P+G W L+ G+SGI + + + A V F Sbjct: 18 RRVVVTGLGMLSPVGNTVESTWKALLAGQSGISLIDHFDTSAYATKFAGLVK------DF 71 Query: 102 NEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVVS 161 N ++ +S+ + + M + I A AM+DSG +E + G AIG G+ L ++ Sbjct: 72 NCEDIISRKEQRKMDAFIQYGIVAGVQAMQDSGLEI-TEENATRIGAAIGSGIGGLGLIE 130 Query: 162 ETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSFR 221 E + G K+SPFFVP +VNM AG ++I Y L+GP+ +++TA T+G H +G + R Sbjct: 131 ENHTSLMNGGPRKISPFFVPSTIVNMVAGHLTIMYGLRGPSISIATAATSGVHNIGHAAR 190 Query: 222 FIAHGDADVMVAGGTDSCISPLSLAGFSRARALST-NSDPKLACRPFHPKRDGFVMGEGA 280 IA+GDADVMVAGG + +PL + GF ARALST N +P+ A RP+ +RDGFV+G+GA Sbjct: 191 IIAYGDADVMVAGGAEKASTPLGVGGFGAARALSTRNDNPQAASRPWDKERDGFVLGDGA 250 Query: 281 AVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGVQPE 340 +LVLEEYEHA +R A+IYAE++G+G+S DA H+T+P G GA MA AL+DAG++ Sbjct: 251 GMLVLEEYEHAKKRGAKIYAELVGFGMSSDAYHMTSPPENGAGAALAMANALRDAGIEAS 310 Query: 341 EISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFTTL 400 +I Y+NAH TSTP GD AE +A+K +F + A + VSSTK TGHLLGAAGAVE+ ++ L Sbjct: 311 QIGYVNAHGTSTPAGDKAEAQAVKTIFGEAASRVLVSSTKSMTGHLLGAAGAVESIYSIL 370 Query: 401 ACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATL 454 A Q +PPT+NLD + DL++VP +A++ + L NSFGFGGTN +L Sbjct: 371 ALRDQAVPPTINLDNPDEGCDLDFVPHEARQVSGMEYT--LCNSFGFGGTNGSL 422 >1OXH-A nrPDB Length = 430 Score = 261 bits (668), Expect = 3e-70, Method: Compositional matrix adjust. Identities = 158/416 (37%), Positives = 233/416 (56%), Gaps = 15/416 (3%) Query: 42 RRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDEGQF 101 RVV+TG G+ +P+G W+ L G+ GI + ++ AA + F Sbjct: 23 NRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHSDFDVHNAAEIQ------DF 76 Query: 102 NEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQS-EADQVATGVAIGMGMIPLEVV 160 + K D + ++ A+ AA+ A+ + ++ D+ VA G+G I + + Sbjct: 77 PFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFGVIVASGIGGI--KEI 134 Query: 161 SETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSF 220 + L KG +V P +PK L NMA+G V++R+ G +++TAC++ A+GD+F Sbjct: 135 EDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSINTACSSSNDAIGDAF 194 Query: 221 RFIAHGDADVMVAGGTDSCISPLSLAGFSRARALSTNSDPKLACRPFHPKRDGFVMGEGA 280 R I G DVM+ GGT++ I+P ++AGF ALST DP A PF R+GFVMGEG+ Sbjct: 195 RSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRASIPFDKDRNGFVMGEGS 254 Query: 281 AVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGVQPE 340 +LVLE EHA +R A I AEV+GYG + DA H+T+P PEG+GA++ + AL++A + PE Sbjct: 255 GMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEGQGAIKAIKLALEEAEISPE 314 Query: 341 EISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFTTL 400 +++Y+NAH TSTP + E+ AI + + VSSTK TGHLLGAAGAVEA T Sbjct: 315 QVAYVNAHGTSTPANEKGESGAIVAVLGKE---VPVSSTKSFTGHLLGAAGAVEAIVTIE 371 Query: 401 ACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCI 456 A + +P T + N V Q + E + ++N+FGFGG NA L Sbjct: 372 AMRHNFVPMTAGTSEVSDYIEANVV--YGQGLEKEIPY-AISNTFGFGGHNAVLAF 424 >4XOX-A nrPDB Length = 404 Score = 228 bits (582), Expect = 3e-60, Method: Compositional matrix adjust. Identities = 147/419 (35%), Positives = 232/419 (55%), Gaps = 26/419 (6%) Query: 42 RRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDEGQF 101 +RVVITG+G+++ +G V L G+SGI + E++K + + + Sbjct: 2 KRVVITGMGIISSIGNNVEEVLASLKAGKSGITA--SEQFKEHGLRSQVW-----GDLKI 54 Query: 102 NEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVVS 161 N + + + ++ M A + E A+ D+G P+ ++ TG+ G G E Sbjct: 55 NPEEHIDRKQMRFMGDAAAYAYLSLEQAIADAGLTPEQVSND-RTGIVAGSGGASSENQV 113 Query: 162 ETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSFR 221 + KG +V P+ VP+ + + + ++ +K++G N+++S+AC T AH +G++ Sbjct: 114 IAVDTQREKGVKRVGPYMVPRTMSSTVSACLATPFKIRGVNYSISSACATSAHCIGNAVE 173 Query: 222 FIAHGDADVMVAGGTDSCISPLSLAGFSRARALST--NSDPKLACRPFHPKRDGFVMGEG 279 I G D++ AGG + ++ F ALST N P+ A R + RDGFV+ G Sbjct: 174 LIQLGKQDIVFAGGGEELYWSQTMM-FDAMGALSTKYNETPEKASRTYDADRDGFVISGG 232 Query: 280 AAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGVQP 339 ++V+EE EHA+ R A+IY E++GYG + D + AP GEGA+RCM A++ GV Sbjct: 233 GGMVVVEELEHALARGAKIYGEIVGYGATSDGYDMVAPS--GEGAIRCMKMAMQ--GV-- 286 Query: 340 EEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFTT 399 ++I YIN H TSTP+GD E AI+ +F + + A+S+TK TGH LGAAG EA ++T Sbjct: 287 DKIDYINTHGTSTPVGDVKELGAIQEVFGGN--SPAISATKAMTGHALGAAGVHEAIYST 344 Query: 400 LACYYQKLPPTLNLDC-SEPEFDLNYV-PLKAQEWKTEKRFIGLTNSFGFGGTNATLCI 456 L ++ + P++N+D E L+ V L+ QE T ++NSFGFGGTNATL I Sbjct: 345 LMLHHGFIAPSINIDTLDEAAQGLDIVTELREQELTTV-----MSNSFGFGGTNATLVI 398 >2GP6-A nrPDB Length = 434 Score = 223 bits (567), Expect = 2e-58, Method: Compositional matrix adjust. Identities = 145/417 (34%), Positives = 221/417 (52%), Gaps = 21/417 (5%) Query: 44 VVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVG---EEYKSIPCSVAAYVPRGSDEGQ 100 VV+TGI + T L W L+ +SGI +L EE+ +P + ++ + Sbjct: 30 VVVTGIAMTTALATDAETTWKLLLDRQSGIRTLDDPFVEEF-DLPVRIGGHLLE-----E 83 Query: 101 FNEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVV 160 F+ Q +++ +++ M M+ + +++G E D V+IG G+ E + Sbjct: 84 FDHQ--LTRIELRRMGYLQRMSTVLSRRLWENAG---SPEVDTNRLMVSIGTGLGSAEEL 138 Query: 161 SETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSF 220 + + + +G VSP V K + N AA V + K +AC +GA A+ ++ Sbjct: 139 VFSYDDMRARGMKAVSPLTVQKYMPNGAAAAVGLERHAKAGVMTPVSACASGAEAIARAW 198 Query: 221 RFIAHGDADVMVAGGTDSCISPLSLAGFSRARAL--STNSDPKLACRPFHPKRDGFVMGE 278 + I G+AD + GG ++ I + +AGF++ R + + N DP ACRPF RDGFV GE Sbjct: 199 QQIVLGEADAAICGGVETRIEAVPIAGFAQMRIVMSTNNDDPAGACRPFDRDRDGFVFGE 258 Query: 279 GAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGVQ 338 G A+L++E EHA R A I A ++G ++ D H+ APDP GE A + A++ AG+ Sbjct: 259 GGALLLIETEEHAKARGANILARIMGASITSDGFHMVAPDPNGERAGHAITRAIQLAGLA 318 Query: 339 PEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFT 398 P +I ++NAHAT T +GD AE +AI + + AV + K A GH +GA GAVE+ T Sbjct: 319 PGDIDHVNAHATGTQVGDLAEGRAINNALGGNRP--AVYAPKSALGHSVGAVGAVESILT 376 Query: 399 TLACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLC 455 LA Q +PPTLNL +PE DL+ V A E + + NSFGFGG N + Sbjct: 377 VLALRDQVIPPTLNLVNLDPEIDLDVV---AGEPRPGNYRYAINNSFGFGGHNVAIA 430 >1TQY-A nrPDB Length = 424 Score = 216 bits (551), Expect = 1e-56, Method: Compositional matrix adjust. Identities = 148/430 (34%), Positives = 212/430 (49%), Gaps = 29/430 (6%) Query: 40 LHRRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDEG 99 + RRVVITG+G+ P G GT W+ L G + + + VAA E Sbjct: 1 MKRRVVITGVGVRAPGGNGTRQFWELLTSGRTATRRISFFDPSPYRSQVAA-------EA 53 Query: 100 QFN--EQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPL 157 F+ + F + ++ M + A+ A A SG P + D GV++G + Sbjct: 54 DFDPVAEGFGPR-ELDRMDRASQFAVACAREAFAASGLDPDT-LDPARVGVSLGSAVAAA 111 Query: 158 EVVSETALNFQTKGYN----------KVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVST 207 + L G + + + VP ++ +V+ +GP VST Sbjct: 112 TSLEREYLLLSDSGRDWEVDAAWLSRHMFDYLVPSVM----PAEVAWAVGAEGPVTMVST 167 Query: 208 ACTTGAHAVGDSFRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALST-NSDPKLACRP 266 CT+G +VG++ R I G ADVM AG D+ I+P+ +A F RA + N DP+ A RP Sbjct: 168 GCTSGLDSVGNAVRAIEEGSADVMFAGAADTPITPIVVACFDAIRATTARNDDPEHASRP 227 Query: 267 FHPKRDGFVMGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALR 326 F RDGFV+ EGAA+ VLE+Y+ A+ R ARI+AE+ GY +A H+T +G Sbjct: 228 FDGTRDGFVLAEGAAMFVLEDYDSALARGARIHAEISGYATRCNAYHMTGLKADGREMAE 287 Query: 327 CMAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHL 386 + AL ++ +I YINAH + T D E A K +HA VSS K GH Sbjct: 288 TIRVALDESRTDATDIDYINAHGSGTRQNDRHETAAYKRALGEHARRTPVSSIKSMVGHS 347 Query: 387 LGAAGAVEAAFTTLACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFG 446 LGA G++E A LA + +PPT NL S+PE DL+YVPL+A+E K LT G Sbjct: 348 LGAIGSLEIAACVLALEHGVVPPTANLRTSDPECDLDYVPLEARERKLRSV---LTVGSG 404 Query: 447 FGGTNATLCI 456 FGG + + + Sbjct: 405 FGGFQSAMVL 414 >3U0E-A nrPDB Length = 428 Score = 215 bits (548), Expect = 2e-56, Method: Compositional matrix adjust. Identities = 147/417 (35%), Positives = 223/417 (53%), Gaps = 22/417 (5%) Query: 42 RRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSI--PCSVAAYVPRGSDEG 99 RRVV+TG+G+V+ +G T V L +SGI EEY + C V G+ + Sbjct: 23 RRVVVTGMGIVSSIGSNTEEVTASLREAKSGISR--AEEYAELGFRCQV-----HGAPD- 74 Query: 100 QFNEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEV 159 + ++ V + ++ T A + A+ D+G + E TG+ +G G Sbjct: 75 -IDIESLVDRRAMRFHGRGTAWNHIAMDQAIADAGL-TEEEVSNERTGIIMGSGGPSTRT 132 Query: 160 VSETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDS 219 + ++A + KG +V PF VPK + + A+ ++ +K+KG N+++S+AC T H +G++ Sbjct: 133 IVDSADITREKGPKRVGPFAVPKAMSSTASATLATFFKIKGINYSISSACATSNHCIGNA 192 Query: 220 FRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALST--NSDPKLACRPFHPKRDGFVMG 277 + I +G D M AGG + LS+ F A+S+ N P A R + RDGFV+ Sbjct: 193 YEMIQYGKQDRMFAGGCEDLDWTLSVL-FDAMGAMSSKYNDTPSTASRAYDKNRDGFVIA 251 Query: 278 EGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGV 337 GA VLVLE+ E A+ R A+IY E++GYG + D + A P GEGA+RCM AL Sbjct: 252 GGAGVLVLEDLETALARGAKIYGEIVGYGATSDGYDMVA--PSGEGAIRCMKMALSTV-- 307 Query: 338 QPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAF 397 +I YIN HATSTP GDA E +AI+ +F +++TK TGH LGA G EA + Sbjct: 308 -TSKIDYINPHATSTPAGDAPEIEAIRQIFGAGDVCPPIAATKSLTGHSLGATGVQEAIY 366 Query: 398 TTLACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATL 454 + L + + +++ +P F +P+ + + L+NSFGFGGTNATL Sbjct: 367 SLLMMQNNFICESAHIEELDPAF--ADMPIVRKRIDNVQLNTVLSNSFGFGGTNATL 421 >5W2O-A nrPDB Length = 439 Score = 214 bits (545), Expect = 6e-56, Method: Compositional matrix adjust. Identities = 145/399 (36%), Positives = 210/399 (52%), Gaps = 23/399 (5%) Query: 63 WDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDEGQFNE--QNFVSKSDIKSMSSPTI 120 W L+ GESGI +L E +V G + + + + D++ MS Sbjct: 56 WKGLLAGESGIHALEDEFVTKWDLAVKI-------GGHLKDPVDSHMGRLDMRRMSYVQR 108 Query: 121 MA--IGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVVSETALNFQTKGYNKVSPF 178 M +G + +S P+ + D+ A V +G G+ E + E+ G KVSP Sbjct: 109 MGKLLGGQ---LWESAGSPEVDPDRFA--VVVGTGLGGAERIVESYDLMNAGGPRKVSPL 163 Query: 179 FVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDS 238 V I+ N AA + ++ + +AC++G+ A+ ++R I GDADV V GG + Sbjct: 164 AVQMIMPNGAAAVIGLQLGARAGVMTPVSACSSGSEAIAHAWRQIVMGDADVAVCGGVEG 223 Query: 239 CISPLSLAGFSRARALST-NSDPKLACRPFHPKRDGFVMGEGAAVLVLEEYEHAVQRRAR 297 I L +A FS RA+ST N +P+ A RPF RDGFV GE A++++E EHA R A+ Sbjct: 224 PIEALPIAAFSMMRAMSTRNDEPERASRPFDKDRDGFVFGEAGALMLIETEEHAKARGAK 283 Query: 298 IYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGVQPEEISYINAHATSTPLGDA 357 A +LG G++ DA H+ AP +G A R M +L+ AG+ P +I ++NAH T+TP+GDA Sbjct: 284 PLARLLGAGITSDAFHMVAPAADGVRAGRAMTRSLELAGLSPADIDHVNAHGTATPIGDA 343 Query: 358 AENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFTTLACYYQKLPPTLNLDCSE 417 AE AI+ D A AV + K A GH +GA GA+E+ T L +PPTLN + + Sbjct: 344 AEANAIRVAGCDQA---AVYAPKSALGHSIGAVGALESVLTVLTLRDGVIPPTLNYETPD 400 Query: 418 PEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCI 456 PE DL+ V A E + + NSFGFGG N L Sbjct: 401 PEIDLDVV---AGEPRYGDYRYAVNNSFGFGGHNVALAF 436 >3OYT-A nrPDB Length = 410 Score = 214 bits (545), Expect = 6e-56, Method: Compositional matrix adjust. Identities = 148/422 (35%), Positives = 221/422 (52%), Gaps = 20/422 (4%) Query: 38 SRLHRRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSD 97 S +R VITG+G+V+ +G V L G SGI +E+K + G Sbjct: 1 SNAMKRAVITGLGIVSSIGNNQQEVLASLQEGRSGIT--FAQEFKDAGMRSHVW---GDV 55 Query: 98 EGQFNEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPL 157 + Q ++ + + ++ MS +I A A + A+ DSG ++ + V G P Sbjct: 56 KLQSEPKDLIDRKVLRFMSDASIYAYLAMQEAIADSGLSDSQVSNFRSGLVVGSGGGSPR 115 Query: 158 EVVSETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVG 217 V+ + +G V P+ V K + + + ++ +K+KG N+++S+AC T AH +G Sbjct: 116 NQVAGSDAMRTPRGLKGVGPYMVTKAMASGVSACLATPFKIKGVNYSISSACATSAHCIG 175 Query: 218 DSFRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALST--NSDPKLACRPFHPKRDGFV 275 + I G D++ AGG + ++ F ALST N P A R + RDGFV Sbjct: 176 HALELIQLGKQDIVFAGGGEELCWEMACE-FDAMGALSTKYNDTPAKASRTYDQDRDGFV 234 Query: 276 MGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDA 335 + G ++V+EE EHA+ R A IYAE++GYG + D + A P GEGA+RCM A+ A Sbjct: 235 IAGGGGMVVVEELEHALARGAHIYAEIVGYGATSDGADMVA--PSGEGAVRCMQMAM--A 290 Query: 336 GVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEA 395 GV I Y+N H TSTP+GD E AI+ +F ++ A+SSTK TGH LGAAG EA Sbjct: 291 GVDT-PIDYMNVHGTSTPVGDVKELGAIREVFGNN--TPAISSTKAMTGHSLGAAGVHEA 347 Query: 396 AFTTLACYYQKLPPTLNLD-CSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATL 454 F+ L + + P++N+D E +N + Q T ++NSFGFGGTNATL Sbjct: 348 IFSLLMVEHGFIAPSINIDNLDEQAQGMNIITETTQRELTTV----MSNSFGFGGTNATL 403 Query: 455 CI 456 + Sbjct: 404 VM 405 >2BZ4-A nrPDB Length = 418 Score = 206 bits (524), Expect = 2e-53, Method: Compositional matrix adjust. Identities = 142/423 (33%), Positives = 220/423 (52%), Gaps = 25/423 (5%) Query: 42 RRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDEGQF 101 +R VITG+G+V+ +G V L G SGI + + V V + Sbjct: 14 KRAVITGLGIVSSIGNNQQEVLASLREGRSGITFSQELKDSGMRSHVWGNV-------KL 66 Query: 102 NEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMG--MIPLEV 159 + + + ++ MS +I A + E A+ D+G P++ + G+ G G +V Sbjct: 67 DTTGLIDRKVVRFMSDASIYAFLSMEQAIADAGLSPEAYQNNPRVGLIAGSGGGSPRFQV 126 Query: 160 VSETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDS 219 A+ +G V P+ V K + + + ++ +K+ G N+++S+AC T AH +G++ Sbjct: 127 FGADAMR-GPRGLKAVGPYVVTKAMASGVSACLATPFKIHGVNYSISSACATSAHCIGNA 185 Query: 220 FRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALST--NSDPKLACRPFHPKRDGFVMG 277 I G D++ AGG + ++ F ALST N P+ A R + RDGFV+ Sbjct: 186 VEQIQLGKQDIVFAGGGEELCWEMACE-FDAMGALSTKYNDTPEKASRTYDAHRDGFVIA 244 Query: 278 EGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGV 337 G ++V+EE EHA+ R A IYAE++GYG + D + A P GEGA+RCM A+ GV Sbjct: 245 GGGGMVVVEELEHALARGAHIYAEIVGYGATSDGADMVA--PSGEGAVRCMKMAMH--GV 300 Query: 338 QPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAF 397 I Y+N+ TSTP+GD E AI+ +F D + A+S+TK TGH LGAAG EA + Sbjct: 301 DT-PIDYLNSQGTSTPVGDVKELAAIREVFGDKSP--AISATKAMTGHSLGAAGVQEAIY 357 Query: 398 TTLACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIG-LTNSFGFGGTNATLCI 456 + L + + P++N++ E D L T++ ++NSFGFGGTNATL + Sbjct: 358 SLLMLEHGFIAPSINIE----ELDEQAAGLNIVTETTDRELTTVMSNSFGFGGTNATLVM 413 Query: 457 AGL 459 L Sbjct: 414 RKL 416 >6QSP-A nrPDB Length = 406 Score = 140 bits (353), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 95/263 (36%), Positives = 131/263 (49%), Gaps = 19/263 (7%) Query: 195 RY-KLKGPNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDSCISPLSLAGFSRARA 253 RY ++GP +STAC++ + A+ R I G D + GG D+ +S + + GF + Sbjct: 159 RYLAIEGPAFTLSTACSSSSRAIISGQRLIEMGLVDAAIVGGADT-LSRMPINGFDSLES 217 Query: 254 LSTNSDPKLACRPFHPKRDGFVMGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGH 313 LS P L C PF R G +GE + +L+L + +LG G S DA H Sbjct: 218 LS----PTL-CEPFCQDRQGITIGEASTLLLLTREPQPI--------ALLGVGESSDAWH 264 Query: 314 ITAPDPEGEGALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYA 373 ++AP PEG GA+ + AL+ AG+ P EI YIN H T T L D E+ I +F ++ Sbjct: 265 MSAPHPEGRGAIAAINMALRKAGISPAEIGYINLHGTGTKLNDQMESIVINQIFGENT-- 322 Query: 374 LAVSSTKGATGHLLGAAGAVEAAFTTLACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWK 433 SSTK TGH LGAAGA EA L P + S + L L Q Sbjct: 323 -PCSSTKYLTGHTLGAAGACEAGLCWLLLTRHLPLPAQDFTRSGIDIALPACGLLTQSQP 381 Query: 434 TEKRFIGLTNSFGFGGTNATLCI 456 EK + ++NSF FGG N +L + Sbjct: 382 LEKPIV-MSNSFAFGGNNTSLIL 403 >1TQY-B nrPDB Length = 415 Score = 122 bits (307), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 103/388 (26%), Positives = 169/388 (43%), Gaps = 20/388 (5%) Query: 42 RRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDEGQF 101 + V+ITG+G+V P G+G W ++ G G+ + + P ++A + F Sbjct: 9 KSVLITGVGVVAPNGLGLAPYWSAVLDGRHGLGPVTRFDVSRYPATLAGQI------DDF 62 Query: 102 NEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVVS 161 + + + + T +A+ AA+ A++D+ P+S D GV + Sbjct: 63 HAPDHIPGRLLPQTDPSTRLALTAADWALQDAKADPESLTDY-DMGVVTANACGGFDFTH 121 Query: 162 ETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSFR 221 ++G VS + + GQ+SIR+ ++GP+ A+ G A+G + R Sbjct: 122 REFRKLWSEGPKSVSVYESFAWFYAVNTGQISIRHGMRGPSSALVAEQAGGLDALGHARR 181 Query: 222 FIAHGDADVMVAGGTDSCISPLSLAGFSRARALSTNSDPKLACRPFHPKRDGFVMGEGAA 281 I G ++V+GG DS + P + +ST +DP A PF + G+V GEG A Sbjct: 182 TIRRG-TPLVVSGGVDSALDPWGWVSQIASGRISTATDPDRAYLPFDERAAGYVPGEGGA 240 Query: 282 VLVLEEYEHAVQR-RARIYAEVLGYGLSGDAGHITAPDP---EGEGALRCMAAALKDAGV 337 +LVLE+ A R R Y E+ G + D P P G R + AL DAG Sbjct: 241 ILVLEDSAAAEARGRHDAYGELAGCASTFD------PAPGSGRPAGLERAIRLALNDAGT 294 Query: 338 QPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAF 397 PE++ + A P DAAE +AI +F + V T TG L G ++ Sbjct: 295 GPEDVDVVFADGAGVPELDAAEARAIGRVFGREGVPVTVPKTT--TGRLYSGGGPLDVVT 352 Query: 398 TTLACYYQKLPPTLNLDCSEPEFDLNYV 425 ++ + PT + E+ ++ V Sbjct: 353 ALMSLREGVIAPTAGVTSVPREYGIDLV 380 >4OQJ-A nrPDB Length = 845 Score = 106 bits (265), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 99/346 (28%), Positives = 153/346 (44%), Gaps = 33/346 (9%) Query: 129 AMKDSGWHPQSEADQVATGVAIGMGMIPLEVVSETALNFQTKGYNKVSPFFVPKILVNMA 188 A++ +G+ PQ ++ +G+ L + E Y S ++++ Sbjct: 117 ALERAGYDPQRGEQRIGVYAGVGLNTYLLHNLGER--------YRTASSVDRYRMMITND 168 Query: 189 AGQVSIR--YKLK--GPNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDSCISPLS 244 V+ R YKL GP+ + +TAC+T AV + + GD + +AG + I Sbjct: 169 KDFVATRTAYKLNLCGPSVSTNTACSTSLVAVHLACLSLLSGDCTMALAGA--AHIQADQ 226 Query: 245 LAGFSRARALSTNSDPKLACRPFHPKRDGFVMGEGAAVLVLEEYEHAVQRRARIYAEVLG 304 G+ + + D CR F K G V+G G +VL+ A+ ++A + G Sbjct: 227 GEGYLHHEGMIFSPDGH--CRAFDAKAQGTVIGNGVGAVVLKRLSDALADGDTVHAVIKG 284 Query: 305 YGLSGDAGH---ITAPDPEGEGALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAENK 361 ++ D TAP +G+ A+ A + D G PE +SY+ AH T+TPLGD E Sbjct: 285 TAVNNDGSDKTGYTAPSVQGQAAVVAEAQEIADVG--PETVSYVEAHGTATPLGDPIEVA 342 Query: 362 AIKHLFKDHAYAL-----AVSSTKGATGHLLGAAGAVEAAFTTLACYYQKLPPTLNLDCS 416 A+ F AL A+ S K GHL AAG T L ++ L P+L + Sbjct: 343 ALNQAFNREGAALAPGSCALGSVKTNVGHLDTAAGMAGLIKTILMLRHRTLVPSLCFEAP 402 Query: 417 EPEFDLN----YVPLKAQEWKT--EKRFIGLTNSFGFGGTNATLCI 456 PE D YV + +EW R G++ SFG GGTNA + + Sbjct: 403 NPEIDFAAGPFYVGTETKEWPAGPTPRRAGVS-SFGIGGTNAHVIV 447 >5ENY-A nrPDB Length = 764 Score = 97.4 bits (241), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 120/456 (26%), Positives = 189/456 (41%), Gaps = 60/456 (13%) Query: 34 TVPI--SRLHRRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSV--- 88 TVP+ R + I G+ P WD L+ + I + IP S Sbjct: 166 TVPVLQDRPEDAIAIVGMSGRYPGARNVREYWDNLVHARNAI--------RDIPTSRWDV 217 Query: 89 -AAYVPRGSDEGQFNEQNFVSKSDIKSMSSPTIMAI--GAAEL--------------AMK 131 Y P + +G+ ++ DI+ P I AEL A + Sbjct: 218 DKYYDPVLNKKGKVYCKSMGMLDDIEHFD-PLFFNIPPSEAELMDPQHRIFLQEGYKAFE 276 Query: 132 DSGWHPQSEADQVATGVAIGMGMIPLEVVSETALNFQTKGYNKVSPFFVPKILVNMAAGQ 191 D+G++ ++ ++ GV +G+ V+ LN Q++ + F + AA + Sbjct: 277 DAGYNART-LNEKKCGVYLGIMSNEYGVM----LNRQSRANATGNSFAI-------AAAR 324 Query: 192 VSIRYKLKGPNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDSCISPLSLAGFSRA 251 + LKGP + TAC++ + + + + + D+ + GG ++P S A Sbjct: 325 IPYFLNLKGPAIPIDTACSSSLVGTHLARQALINKEIDMALVGGVSLYLTPESYMSMCEA 384 Query: 252 RALSTNSDPKLACRPFHPKRDGFVMGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGD- 310 LS P C+ F +GFV GEGA LVL+ + A R IY ++G G++ D Sbjct: 385 GMLS----PDGQCKAFDNGANGFVPGEGAGALVLKRLKDAEADRDHIYGIIIGSGINQDG 440 Query: 311 -AGHITAPDPEGEGALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFK- 368 ITAP + + L + G+ PE ISY+ H T T GD E +A+ +F+ Sbjct: 441 KTNGITAPSAKSQMDLE--RDIYETYGIHPESISYVEMHGTGTKQGDPIELEALSTVFQE 498 Query: 369 --DHAYALAVSSTKGATGHLLGAAGAVEAAFTTLACYYQKLPPTLNLDCSEPEFDLNYVP 426 D A+ S K GH AAG L ++ L PTLN F+ + P Sbjct: 499 KTDKKQFCAIGSVKSNIGHTSAAAGVAGVQKVLLCMNHKTLVPTLNFTTPNEHFEFEHSP 558 Query: 427 L----KAQEWKTE--KRFIGLTNSFGFGGTNATLCI 456 L + + W+T K +SFG+ GTNA + I Sbjct: 559 LYVNTELKPWETADGKPRRACVSSFGYSGTNAHIVI 594 >4CW4-A nrPDB Length = 639 Score = 65.1 bits (157), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 67/273 (24%), Positives = 123/273 (45%), Gaps = 22/273 (8%) Query: 200 GPNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALST--- 256 G +++ AC T + + I G A V++ G +++ I P + G+S AL+T Sbjct: 277 GMTGSITGACATFLYNLQKGIDVITSGQARVVIVGNSEAPILPECIEGYSAMGALATEEG 336 Query: 257 --------NSDPKLACRPFHPKRDGFVMGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLS 308 + D + A RPF + GF + E + +VL + E A++ A I+ V ++ Sbjct: 337 LRLIEGRDDVDFRRASRPFG-ENCGFTLAESSQYVVLMDDELALRLGADIHGAVTDVFIN 395 Query: 309 GDA--GHITAPDPEGEGAL-RCMAAALKDAGVQP-EEISYINAHATSTPLGDAAENKAIK 364 D I+AP P + + +A+A++ G+ S+++AH +STP E++ + Sbjct: 396 ADGFKKSISAPGPGNYLTVAKAVASAVQIVGLDTVRHASFVHAHGSSTPANRVTESEILD 455 Query: 365 HLFKDHAYAL---AVSSTKGATGHLLGAAGAVEAAFTTLACYYQKLPPTLNLDCSEPEFD 421 + A+ + V++ K GH L A A + Y LP +D + Sbjct: 456 RVAS--AFGIDGWPVTAVKAYVGHSLATASADQLISALGTFKYGILPGIKTIDKVADDVH 513 Query: 422 LNYVPLKAQEWKTEKRF-IGLTNSFGFGGTNAT 453 + + ++ + +K + NS GFGG NA+ Sbjct: 514 QQRLSISNRDMRQDKPLEVCFINSKGFGGNNAS 546 >4E1L-A nrPDB Length = 395 Score = 41.6 bits (96), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 42/144 (29%), Positives = 65/144 (45%), Gaps = 19/144 (13%) Query: 270 KRDGFV-------MGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGE 322 K+DG V + +GAA+L+L + A + R A++ Y +G P+ G Sbjct: 240 KKDGTVTAGNASGINDGAAMLILMSQQKADELGIRPLAKIKSYASAG-----VEPEVMGT 294 Query: 323 GALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGA 382 G + ALK AG+ +I I A+ AA+ A+K+ + + L V+ A Sbjct: 295 GPIPATRKALKKAGLSINDIDLIEANEAF-----AAQALAVKNELQIDSSKLNVNGGAIA 349 Query: 383 TGHLLGAAGAVEAAFTTLACYYQK 406 GH +GA+GA TL QK Sbjct: 350 LGHPIGASGA--RILVTLIYEMQK 371 Score = 30.8 bits (68), Expect = 1.2, Method: Compositional matrix adjust. Identities = 13/38 (34%), Positives = 25/38 (65%) Query: 201 PNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDS 238 P++ V+ C +G +V + + I G+ DV++AGGT++ Sbjct: 83 PSYTVNKLCGSGLKSVQLAAQSITSGENDVVIAGGTEN 120 >4N44-A nrPDB Length = 400 Score = 35.0 bits (79), Expect = 0.062, Method: Compositional matrix adjust. Identities = 46/190 (24%), Positives = 77/190 (40%), Gaps = 25/190 (13%) Query: 218 DSFRFIAHGDADVMVAGGT-DSCISPLSLAGFSRARALSTNSDPKLACR-----PFHP-- 269 D F + A+ + G I P+ + G + T+ P+ P Sbjct: 176 DEFALASQKKAEEAIKSGQFKDEIVPVVIKGRKGETVVDTDEHPRFGSTIEGLAKLKPAF 235 Query: 270 KRDGFV-------MGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGE 322 K+DG V + + AAVLV+ E A + + A+++ YG +G P G Sbjct: 236 KKDGTVTAGNASGLNDCAAVLVIMSAEKAKELGVKPLAKIVSYGSAG-----VDPAIMGY 290 Query: 323 GALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGA 382 G AA++ AG +E+ I ++ AA++ A+ K + V+ A Sbjct: 291 GPFYATKAAIEKAGWTVDELDLIESNEAF-----AAQSLAVAKDLKFDMNKVNVNGGAIA 345 Query: 383 TGHLLGAAGA 392 GH +GA+GA Sbjct: 346 LGHPIGASGA 355 Score = 32.0 bits (71), Expect = 0.60, Method: Compositional matrix adjust. Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 9/58 (15%) Query: 201 PNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALSTNS 258 P ++ C +G V + + I GDADV++AGG ++ SRA L+ N+ Sbjct: 80 PAMTINKVCGSGLRTVSLAAQIIKAGDADVIIAGGMEN---------MSRAPYLANNA 128 >5ZQZ-B nrPDB Length = 474 Score = 34.3 bits (77), Expect = 0.12, Method: Compositional matrix adjust. Identities = 16/39 (41%), Positives = 21/39 (53%) Query: 199 KGPNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTD 237 K P H V+ AC + A+ IA G DV+VAGG + Sbjct: 128 KTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVE 166 >4DD5-A nrPDB Length = 396 Score = 32.7 bits (73), Expect = 0.31, Method: Compositional matrix adjust. Identities = 15/43 (34%), Positives = 26/43 (60%), Gaps = 1/43 (2%) Query: 201 PNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDS-CISP 242 P ++ C +G +V + + IA GDAD+M+ GG ++ +SP Sbjct: 85 PAMTINIVCGSGLRSVSMASQLIALGDADIMLVGGAENMSMSP 127 Score = 29.3 bits (64), Expect = 3.5, Method: Compositional matrix adjust. Identities = 39/140 (27%), Positives = 61/140 (43%), Gaps = 19/140 (13%) Query: 261 KLA-CRPFHPKRDGFV-------MGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAG 312 KLA RP K+DG V + +GAA+LV+ E A + A ++ YG +G Sbjct: 232 KLAKLRPAF-KKDGTVTAGNASGINDGAAMLVVMAKEKAEELGIEPLATIVSYGTAG--- 287 Query: 313 HITAPDPEGEGALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAY 372 P G G + AL+ A + E+I + A+ AA++ A+ Sbjct: 288 --VDPKIMGYGPVPATKKALEAANMTIEDIDLVEANEAF-----AAQSVAVIRDLNIDMN 340 Query: 373 ALAVSSTKGATGHLLGAAGA 392 + V+ A GH +G +GA Sbjct: 341 KVNVNGGAIAIGHPIGCSGA 360 >5LP7-H nrPDB Length = 393 Score = 31.2 bits (69), Expect = 0.98, Method: Compositional matrix adjust. Identities = 20/63 (31%), Positives = 33/63 (52%), Gaps = 7/63 (11%) Query: 183 ILVNMAAGQVSIRY--KLKG-----PNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGG 235 ++V +GQ+ R +L G P+ ++ C +G AV + I DAD++VAGG Sbjct: 55 MVVQAGSGQIPSRQAARLAGMPWSVPSETLNKVCASGLRAVTLCDQMIRAQDADILVAGG 114 Query: 236 TDS 238 +S Sbjct: 115 MES 117 >6ARG-A nrPDB Length = 399 Score = 30.4 bits (67), Expect = 1.9, Method: Compositional matrix adjust. Identities = 15/34 (44%), Positives = 22/34 (64%) Query: 205 VSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDS 238 V+ C +G A+ + I G+ADV+VAGGT+S Sbjct: 89 VNKVCASGLKAIILGAQTIMTGNADVVVAGGTES 122 >2IBU-A nrPDB Length = 395 Score = 29.6 bits (65), Expect = 2.5, Method: Compositional matrix adjust. Identities = 20/56 (35%), Positives = 27/56 (48%), Gaps = 7/56 (12%) Query: 190 GQVSIRYKLKGPNHAVSTACTT-------GAHAVGDSFRFIAHGDADVMVAGGTDS 238 GQ R + G +ST CTT G A+ + + + G DVMVAGG +S Sbjct: 68 GQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMES 123 >3SS6-A nrPDB Length = 394 Score = 28.9 bits (63), Expect = 4.6, Method: Compositional matrix adjust. Identities = 31/119 (26%), Positives = 52/119 (43%), Gaps = 16/119 (13%) Query: 233 AGGTDSCISPLSLAGFSRARALSTNSDP-------KLACRPFHPKRDGFV-------MGE 278 +G D I P+++ + S + P KLA ++DG V + + Sbjct: 194 SGYFDDQIVPITIKERRKEVVFSKDEHPRADITAEKLAGLKPAFRKDGSVTAGNASGLND 253 Query: 279 GAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHI--TAPDPEGEGALRCMAAALKDA 335 G+AVLVL E A ++ + A ++GY ++G I P P L + +L+DA Sbjct: 254 GSAVLVLMSEEKAKEKGLQPLARIVGYSVAGVDPKIMGIGPAPAIRKGLEKVDWSLEDA 312 >6BN2-A nrPDB Length = 401 Score = 28.9 bits (63), Expect = 4.7, Method: Compositional matrix adjust. Identities = 13/38 (34%), Positives = 22/38 (57%) Query: 201 PNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDS 238 P AV+ C +G AV + + + GD + +VAGG ++ Sbjct: 88 PTTAVNKVCASGMKAVMMAAQAVKAGDVEAIVAGGMEN 125 >1NL7-A nrPDB Length = 392 Score = 28.9 bits (63), Expect = 5.0, Method: Compositional matrix adjust. Identities = 14/30 (46%), Positives = 19/30 (63%) Query: 209 CTTGAHAVGDSFRFIAHGDADVMVAGGTDS 238 C +G AV + IA GDA ++VAGG +S Sbjct: 89 CGSGLRAVALGMQQIATGDASIIVAGGMES 118 >6FKX-A nrPDB Length = 324 Score = 28.5 bits (62), Expect = 6.9, Method: Compositional matrix adjust. Identities = 25/81 (30%), Positives = 34/81 (41%), Gaps = 1/81 (1%) Query: 323 GALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHA-YALAVSSTKG 381 AL C A G P E + ++ DAA+N A++HLF D A A V + Sbjct: 117 AALDCRGQAGLSVGEAPVENWSMASYLLRGIDDDAADNLALRHLFLDTARLAQIVLAMDD 176 Query: 382 ATGHLLGAAGAVEAAFTTLAC 402 + A G + TLAC Sbjct: 177 VDPDRVAATGYSQGGGLTLAC 197 >4FFM-A nrPDB Length = 363 Score = 28.5 bits (62), Expect = 7.0, Method: Compositional matrix adjust. Identities = 16/62 (25%), Positives = 31/62 (50%), Gaps = 10/62 (16%) Query: 43 RVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDEGQFN 102 R G+ + + + +++ L+ GE+G++ VGE+ S+ GSD G+F Sbjct: 266 RAFTDGVEEIRAIPENKYCIYEHLMFGENGVLIPVGEQVLSM----------GSDYGKFY 315 Query: 103 EQ 104 E+ Sbjct: 316 EE 317 >4C2K-A nrPDB Length = 417 Score = 28.1 bits (61), Expect = 7.8, Method: Compositional matrix adjust. Identities = 30/130 (23%), Positives = 55/130 (42%), Gaps = 17/130 (13%) Query: 270 KRDGFV-------MGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGE 322 K+DG V + +GA +++ + + A ++GY +SG P G Sbjct: 260 KKDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSG-----CDPSIMGI 314 Query: 323 GALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGA 382 G + ++ ALK AG+ +++ + + P A E + K + A+ A Sbjct: 315 GPVPAISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAI-----A 369 Query: 383 TGHLLGAAGA 392 GH LG +G+ Sbjct: 370 LGHPLGGSGS 379 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4LS7-A nrPDB 562 e-160 2IWZ-A nrPDB 559 e-160 1E5M-A nrPDB 535 e-152 3O04-A nrPDB 535 e-152 2GQD-A nrPDB 531 e-151 1J3N-A nrPDB 522 e-148 4R8E-A nrPDB 521 e-148 4JRH-A nrPDB 519 e-147 4JPF-A nrPDB 519 e-147 4JGA-A nrPDB 517 e-147 4QAV-A nrPDB 510 e-145 3KZU-A nrPDB 499 e-142 3HO9-A nrPDB 498 e-141 2IX4-A nrPDB 495 e-140 3E60-A nrPDB 483 e-137 1OXH-A nrPDB 481 e-136 4DDO-A nrPDB 451 e-127 4XOX-A nrPDB 445 e-125 3U0E-A nrPDB 428 e-120 3OYT-A nrPDB 427 e-120 2BZ4-A nrPDB 424 e-119 1TQY-A nrPDB 417 e-117 2GP6-A nrPDB 409 e-114 5W2O-A nrPDB 406 e-113 1TQY-B nrPDB 362 e-100 5ENY-A nrPDB 333 8e-92 4OQJ-A nrPDB 292 2e-79 6QSP-A nrPDB 275 3e-74 4CW4-A nrPDB 257 7e-69 4E1L-A nrPDB 103 2e-22 Sequences not found previously or not previously below threshold: 4DD5-A nrPDB 83 3e-16 4WYS-A nrPDB 81 1e-15 4N44-A nrPDB 77 2e-14 4NZS-A nrPDB 75 5e-14 1NL7-A nrPDB 74 2e-13 1WL4-A nrPDB 71 8e-13 4C2K-A nrPDB 71 1e-12 3SS6-A nrPDB 70 3e-12 6BN2-A nrPDB 66 3e-11 1ULQ-A nrPDB 65 6e-11 5LP7-H nrPDB 64 2e-10 1WDK-C nrPDB 59 5e-09 5CBQ-A nrPDB 59 6e-09 2WUA-A nrPDB 57 2e-08 2C7Y-A nrPDB 57 2e-08 4O9A-A nrPDB 56 3e-08 3GOA-A nrPDB 56 3e-08 3SVK-A nrPDB 53 3e-07 5XYJ-B nrPDB 53 3e-07 2IIK-A nrPDB 52 4e-07 2IBU-A nrPDB 52 5e-07 6BJB-A nrPDB 52 6e-07 6ARG-A nrPDB 52 6e-07 2EBD-A nrPDB 50 2e-06 4B3J-C nrPDB 49 3e-06 6BJA-A nrPDB 49 4e-06 4UBW-A nrPDB 46 4e-05 1PXT-A nrPDB 43 2e-04 5ZQZ-B nrPDB 42 7e-04 4YZO-A nrPDB 41 9e-04 4X0O-A nrPDB 40 0.002 4BI9-A nrPDB 40 0.002 2AJ9-A nrPDB 40 0.002 4NHD-A nrPDB 39 0.004 4EWP-A nrPDB 39 0.005 6ESQ-A nrPDB 38 0.008 4U4E-A nrPDB 38 0.009 4ANI-C nrPDB 37 0.023 5M3K-C nrPDB 37 0.024 5BNS-A nrPDB 35 0.058 1UB7-A nrPDB 35 0.068 5LNQ-A nrPDB 34 0.11 6HRV-A nrPDB 34 0.15 5BQS-A nrPDB 34 0.18 4DFE-A nrPDB 33 0.23 5VXG-A nrPDB 33 0.23 1D4E-A nrPDB 33 0.26 4YLT-A nrPDB 33 0.34 3IL7-A nrPDB 32 0.41 3IL4-A nrPDB 32 0.44 3H76-A nrPDB 32 0.56 4Q4K-A nrPDB 32 0.63 3IL3-A nrPDB 32 0.74 6EC3-A nrPDB 32 0.75 3IP8-A nrPDB 31 0.87 4O5M-A nrPDB 31 1.1 1W66-A nrPDB 31 1.3 1MZJ-A nrPDB 31 1.4 4KTO-A nrPDB 30 1.6 6ET0-A nrPDB 30 1.7 3LS2-A nrPDB 30 1.8 3V7I-A nrPDB 30 2.0 4NQ3-A nrPDB 30 2.3 3MKV-A nrPDB 30 2.9 4V6K-BO nrPDB 29 3.6 2WOQ-A nrPDB 29 4.4 4YUC-A nrPDB 29 4.5 1E9Y-B nrPDB 29 4.6 5YA1-A nrPDB 29 4.8 3LM6-A nrPDB 29 4.8 5BY7-A nrPDB 29 5.2 2R9Z-A nrPDB 28 6.1 2DKD-A nrPDB 28 6.7 6ESQ-I nrPDB 28 7.5 3HMU-A nrPDB 28 8.3 3HQ1-A nrPDB 28 8.8 5YO9-A nrPDB 28 9.5 >4LS7-A nrPDB Length = 426 Score = 562 bits (1449), Expect = e-160, Method: Composition-based stats. Identities = 199/422 (47%), Positives = 265/422 (62%), Gaps = 10/422 (2%) Query: 37 ISRLHRRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGS 96 I +RVV+TG+G ++PLG W+ I G SGI + + + P VAA + Sbjct: 12 IQMTKKRVVVTGLGALSPLGNDVDTSWNNAINGVSGIGPITRVDAEEYPAKVAAELK--- 68 Query: 97 DEGQFNEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIP 156 FN ++++ K + + M T A+ AA++A++D+ + E GV +G G+ Sbjct: 69 ---DFNVEDYMDKKEARKMDRFTQYAVVAAKMAVEDADLNITDEI-APRVGVWVGSGIGG 124 Query: 157 LEVVSETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAV 216 LE + F TKG +VSPFFVP ++ +MA GQ+SI KG N TAC TG +++ Sbjct: 125 LETLESQFEIFLTKGPRRVSPFFVPMMIPDMATGQISIALGAKGVNSCTVTACATGTNSI 184 Query: 217 GDSFRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALSTNSDPKLACRPFHPKRDGFVM 276 GD+F+ I GDADVMV GGT++ ++ +S AGFS +ALSTN DPK A RPF RDGFVM Sbjct: 185 GDAFKVIQRGDADVMVTGGTEAPLTRMSFAGFSANKALSTNPDPKTASRPFDKNRDGFVM 244 Query: 277 GEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAG 336 GEGA ++VLEE EHA+ R A+IY E++GYG +GDA HITAP +GEG R M A+KDAG Sbjct: 245 GEGAGIIVLEELEHALARGAKIYGEIVGYGSTGDAYHITAPAQDGEGGARAMQEAIKDAG 304 Query: 337 VQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAA 396 + PEEI YINAH TST D E AIK +F +HA+ LAVSSTK TGHLLGAAG +EA Sbjct: 305 IAPEEIDYINAHGTSTYYNDKYETMAIKTVFGEHAHKLAVSSTKSMTGHLLGAAGGIEAI 364 Query: 397 FTTLACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCI 456 F+ LA +PPT+N+ + E DL+YVP +A+ + L+NS GFGG NATL Sbjct: 365 FSILAIKEGVIPPTINIQTPDEECDLDYVPDEARRQELN---YVLSNSLGFGGHNATLIF 421 Query: 457 AG 458 Sbjct: 422 KK 423 >2IWZ-A nrPDB Length = 438 Score = 559 bits (1441), Expect = e-160, Method: Composition-based stats. Identities = 422/422 (100%), Positives = 422/422 (100%) Query: 38 SRLHRRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSD 97 SRLHRRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSD Sbjct: 17 SRLHRRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSD 76 Query: 98 EGQFNEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPL 157 EGQFNEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPL Sbjct: 77 EGQFNEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPL 136 Query: 158 EVVSETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVG 217 EVVSETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVG Sbjct: 137 EVVSETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVG 196 Query: 218 DSFRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALSTNSDPKLACRPFHPKRDGFVMG 277 DSFRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALSTNSDPKLACRPFHPKRDGFVMG Sbjct: 197 DSFRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALSTNSDPKLACRPFHPKRDGFVMG 256 Query: 278 EGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGV 337 EGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGV Sbjct: 257 EGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGV 316 Query: 338 QPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAF 397 QPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAF Sbjct: 317 QPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAF 376 Query: 398 TTLACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCIA 457 TTLACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCIA Sbjct: 377 TTLACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCIA 436 Query: 458 GL 459 GL Sbjct: 437 GL 438 >1E5M-A nrPDB Length = 416 Score = 535 bits (1379), Expect = e-152, Method: Composition-based stats. Identities = 182/419 (43%), Positives = 257/419 (61%), Gaps = 11/419 (2%) Query: 41 HRRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDEGQ 100 +RVV+TG+G +TP+G W L+ G +GI + + C V Sbjct: 6 KKRVVVTGLGAITPIGNTLQDYWQGLMEGRNGIGPITRFDASDQACRFGGEVK------D 59 Query: 101 FNEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVV 160 F+ F+ + + K M A+ A++ A+ D+ +E + GV IG G+ L+V+ Sbjct: 60 FDATQFLDRKEAKRMDRFCHFAVCASQQAINDAKLVI-NELNADEIGVLIGTGIGGLKVL 118 Query: 161 SETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSF 220 + KG ++ SPF +P ++ NMA+G +I KGPN+ TAC G++A+GD+F Sbjct: 119 EDQQTILLDKGPSRCSPFMIPMMIANMASGLTAINLGAKGPNNCTVTACAAGSNAIGDAF 178 Query: 221 RFIAHGDADVMVAGGTDSCISPLSLAGFSRARALST-NSDPKLACRPFHPKRDGFVMGEG 279 R + +G A M+ GGT++ I+PLS AGF+ ARALS N DP A RPF RDGFVMGEG Sbjct: 179 RLVQNGYAKAMICGGTEAAITPLSYAGFASARALSFRNDDPLHASRPFDKDRDGFVMGEG 238 Query: 280 AAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGVQP 339 + +L+LEE E A+ R A+IY E++GY ++ DA HITAP P+G GA R +A ALKD+G++P Sbjct: 239 SGILILEELESALARGAKIYGEMVGYAMTCDAYHITAPVPDGRGATRAIAWALKDSGLKP 298 Query: 340 EEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFTT 399 E +SYINAH TSTP D E +AIK +HAY +AVSSTK TGHLLG +G +EA T Sbjct: 299 EMVSYINAHGTSTPANDVTETRAIKQALGNHAYNIAVSSTKSMTGHLLGGSGGIEAVATV 358 Query: 400 LACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCIAG 458 +A K+PPT+NL+ +PE DL+YVP +++ + + L+NSFGFGG N TL Sbjct: 359 MAIAEDKVPPTINLENPDPECDLDYVPGQSRALIVD---VALSNSFGFGGHNVTLAFKK 414 >3O04-A nrPDB Length = 413 Score = 535 bits (1379), Expect = e-152, Method: Composition-based stats. Identities = 186/419 (44%), Positives = 261/419 (62%), Gaps = 10/419 (2%) Query: 41 HRRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDEGQ 100 RRVV+TGIG VTP+G W+ G +G+ + P +AA + Sbjct: 3 KRRVVVTGIGAVTPIGNDAETSWENAKKGVNGVAKMTRLNPDDFPVKIAAELK------D 56 Query: 101 FNEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVV 160 F+ + ++ K + + M T AI +AE+A++DSG +++ GV IG G+ +E Sbjct: 57 FDVEKYLEKKEARKMDRFTHYAIASAEMAVQDSGLVID-DSNANRVGVWIGSGIGGMETF 115 Query: 161 SETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSF 220 F +G+ +VSPFFVP ++ +M +GQVSIR+ KG N TAC T +++GD+F Sbjct: 116 ETQYEIFLNRGHRRVSPFFVPMMIPDMGSGQVSIRFGAKGINSTTVTACATATNSIGDAF 175 Query: 221 RFIAHGDADVMVAGGTDSCISPLSLAGFSRARALSTNSDPKLACRPFHPKRDGFVMGEGA 280 + I GDAD M+ GG ++ I+ +SLAGF+ +ALS N DP+ ACRPF RDGF++GEGA Sbjct: 176 KVIERGDADAMITGGAEAPITKMSLAGFTANKALSLNPDPETACRPFDKDRDGFIIGEGA 235 Query: 281 AVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGVQPE 340 +++LEEYEHA R A+IYAE++GYG +GDA HITAP P GEGA R M A+ DAG+ P+ Sbjct: 236 GIVILEEYEHAKARGAKIYAEIVGYGATGDAYHITAPAPNGEGAARAMKMAIDDAGLTPD 295 Query: 341 EISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFTTL 400 ++ YINAH TSTP D E +AIK +F +HA LA+SSTK TGH LGA+G +EA F L Sbjct: 296 KVDYINAHGTSTPYNDEYETQAIKTVFGEHAKKLAISSTKSMTGHTLGASGGIEAIFALL 355 Query: 401 ACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCIAGL 459 + PT++L + DL+YVP +A+E + ++NSFGFGG NATL + Sbjct: 356 TIRDNIIAPTIHLKNQDEVCDLDYVPNEARE---ANVNVVISNSFGFGGHNATLVFKRI 411 >2GQD-A nrPDB Length = 437 Score = 531 bits (1369), Expect = e-151, Method: Composition-based stats. Identities = 185/419 (44%), Positives = 255/419 (60%), Gaps = 10/419 (2%) Query: 41 HRRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDEGQ 100 ++RVVITG+G ++P+G W+ + G +GI + + + +A + Sbjct: 27 NKRVVITGMGALSPIGNDVKTTWENALKGVNGIDKITRIDTEPYSVHLAGELK------N 80 Query: 101 FNEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVV 160 FN ++ + K + + M T AI AA A+KD+ GV IG G+ +E Sbjct: 81 FNIEDHIDKKEARRMDRFTQYAIVAAREAVKDAQLDINENT-ADRIGVWIGSGIGGMETF 139 Query: 161 SETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSF 220 KG +VSPFFVP ++ +MA GQVSI KGPN A TAC TG +++G++F Sbjct: 140 EIAHKQLMDKGPRRVSPFFVPMLIPDMATGQVSIDLGAKGPNGATVTACATGTNSIGEAF 199 Query: 221 RFIAHGDADVMVAGGTDSCISPLSLAGFSRARALSTNSDPKLACRPFHPKRDGFVMGEGA 280 + + GDAD M+ GGT++ I+ +++AGFS +RALSTN D + ACRPF RDGFVMGEGA Sbjct: 200 KIVQRGDADAMITGGTEAPITHMAIAGFSASRALSTNDDIETACRPFQEGRDGFVMGEGA 259 Query: 281 AVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGVQPE 340 +LV+E E A R A IYAE++GYG +GDA HITAP PEGEG R M AA+ DAG++P+ Sbjct: 260 GILVIESLESAQARGANIYAEIVGYGTTGDAYHITAPAPEGEGGSRAMQAAMDDAGIEPK 319 Query: 341 EISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFTTL 400 ++ Y+NAH TSTP+GD E KAIK+ F + A L VSSTK TGHLLGA G +EA F+ L Sbjct: 320 DVQYLNAHGTSTPVGDLNEVKAIKNTFGEAAKHLKVSSTKSMTGHLLGATGGIEAIFSAL 379 Query: 401 ACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCIAGL 459 + K+ PT++ +PE DL+ VP +AQ+ ++NS GFGG NA L Sbjct: 380 SIKDSKVAPTIHAVTPDPECDLDIVPNEAQDLDIT---YAMSNSLGFGGHNAVLVFKKF 435 >1J3N-A nrPDB Length = 408 Score = 522 bits (1345), Expect = e-148, Method: Composition-based stats. Identities = 193/420 (45%), Positives = 270/420 (64%), Gaps = 13/420 (3%) Query: 41 HRRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDEGQ 100 RRVV+TG+G +TP+GVG + G+SG+ + + ++P +AA V Sbjct: 1 MRRVVVTGLGALTPIGVGQEAFHKAQLAGKSGVRPITRFDASALPVRIAAEV-------D 53 Query: 101 FNEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVV 160 + ++ + +++ + A+ AA+LA++D+G P+ + D G +G G+ +E Sbjct: 54 VDPGAYLDRKELRRLDRFVQYALIAAQLALEDAGLKPE-DLDPERVGTLVGTGIGGMETW 112 Query: 161 SETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSF 220 + F +G N++SPFF+P ++ NMA+ +++RY GP+ V TAC TGA A+G + Sbjct: 113 EAQSRVFLERGPNRISPFFIPMMIANMASAHIAMRYGFTGPSSTVVTACATGADALGSAL 172 Query: 221 RFIAHGDADVMVAGGTDSCISPLSLAGFSRARALST-NSDPKLACRPFHPKRDGFVMGEG 279 R I G+AD+++AGGT++ I+P+++ F+ RALST N +P+ A RPF RDGFVMGEG Sbjct: 173 RMIQLGEADLVLAGGTEAAITPMAIGAFAVMRALSTRNEEPEKASRPFTLSRDGFVMGEG 232 Query: 280 AAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGVQP 339 A VLVLE YEHA +R ARIYAE++G+G S DA HIT P PEG+GA MA ALKDAG+ P Sbjct: 233 AGVLVLEAYEHAKKRGARIYAELVGFGRSADAHHITEPHPEGKGAALAMARALKDAGIAP 292 Query: 340 EEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFTT 399 E++ YINAH TSTP+GD AE AIK +F DHA L VSSTK GHLLGAAGAVEA T Sbjct: 293 EQVGYINAHGTSTPVGDRAEVLAIKRVFGDHAKRLMVSSTKSMIGHLLGAAGAVEAIATV 352 Query: 400 LACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCIAGL 459 A Y+ +PPT+NL+ +PE DL++VP E + K L+NSF FGG NA L + Sbjct: 353 QALYHGVIPPTINLEDPDPELDLDFVP----EPREAKVDYALSNSFAFGGHNAVLAFKRV 408 >4R8E-A nrPDB Length = 413 Score = 521 bits (1341), Expect = e-148, Method: Composition-based stats. Identities = 191/422 (45%), Positives = 266/422 (63%), Gaps = 10/422 (2%) Query: 39 RLHRRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDE 98 RRVV+TG+G+++P+G W ++ G+SGI + + + A V Sbjct: 1 MSKRRVVVTGLGMLSPVGNTVESTWKAVLAGQSGISLIDHFDTSAYATRFAGLVK----- 55 Query: 99 GQFNEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLE 158 FN ++++S+ D + M + + A AM+D+G +EA+ G AIG G+ L Sbjct: 56 -DFNCEDYISRKDARKMDAFIQYGVAAGMQAMQDAGLDI-TEANASRIGAAIGSGIGGLG 113 Query: 159 VVSETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGD 218 ++ E G K+SPFFVP +VNM AG ++I Y L+GP+ +++TACT+G H +G Sbjct: 114 LIEENHTALVNGGPRKISPFFVPSTIVNMIAGHLTIMYGLRGPSISIATACTSGVHNIGH 173 Query: 219 SFRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALST-NSDPKLACRPFHPKRDGFVMG 277 + R IA+ DADVMVAGG + +PL + GF ARALST N +P+ A RP+ RDGFV+G Sbjct: 174 AARIIAYNDADVMVAGGAEKASTPLGVGGFGAARALSTRNDNPQAASRPWDKDRDGFVLG 233 Query: 278 EGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGV 337 +GA ++VLEEYEHA +R A+IYAEV+G+G+S DA H+T+P +G GA M AL+DAG+ Sbjct: 234 DGAGMMVLEEYEHAKKRGAKIYAEVVGFGMSSDAYHMTSPPEDGSGAALAMVNALRDAGI 293 Query: 338 QPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAF 397 +I YINAH TSTP GD AE +A+K +F + AY + VSSTK TGHLLGAAGAVE+ F Sbjct: 294 TTSQIGYINAHGTSTPAGDKAETQAVKSVFGEDAYKVMVSSTKSMTGHLLGAAGAVESIF 353 Query: 398 TTLACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCIA 457 T LA Q +P T+NLD + DL+YVP A++ K L NSFGFGGTN +L Sbjct: 354 TVLALRDQAIPATINLDNPDEGCDLDYVPHDARQVK--DMEYTLCNSFGFGGTNGSLVFR 411 Query: 458 GL 459 + Sbjct: 412 KV 413 >4JRH-A nrPDB Length = 417 Score = 519 bits (1336), Expect = e-147, Method: Composition-based stats. Identities = 195/424 (45%), Positives = 262/424 (61%), Gaps = 11/424 (2%) Query: 38 SRLHRRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSD 97 + RRVV+TG+G+++P+G W L+ G+SGIV++ + + A V Sbjct: 3 AMSKRRVVVTGMGMLSPVGNTVESSWKALLAGQSGIVNIEHFDTTNFSTRFAGLVK---- 58 Query: 98 EGQFNEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPL 157 F+ + ++SK D + M I A A++DSG +E + GVAIG G+ L Sbjct: 59 --GFDCEQYMSKKDARKMDLFIQYGIAAGIQALEDSGLEV-NEENAARIGVAIGSGIGGL 115 Query: 158 EVVSETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVG 217 E++ KG KVSPFFVP +VNM AG +SI L+GPN A+STACTTG H +G Sbjct: 116 ELIETGHQALIEKGPRKVSPFFVPSTIVNMIAGNLSIMRGLRGPNIAISTACTTGLHNIG 175 Query: 218 DSFRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALST-NSDPKLACRPFHPKRDGFVM 276 + R IA+GDAD MVAGG + +PL +AGF A+ALST N +P+ A RP+ RDGFV+ Sbjct: 176 HAARMIAYGDADAMVAGGAEKASTPLGMAGFGAAKALSTRNDEPQKASRPWDKDRDGFVL 235 Query: 277 GEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAG 336 G+GA ++VLEEYEHA R A+IYAEV+G+G+SGDA H+T+P +G G M AA++DAG Sbjct: 236 GDGAGIMVLEEYEHAKARGAKIYAEVVGFGMSGDAYHMTSPSEDGSGGALAMEAAMRDAG 295 Query: 337 VQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYA-LAVSSTKGATGHLLGAAGAVEA 395 V E+I Y+NAH TSTP GD AE K IK + + VSSTK TGHLLGAAG+VEA Sbjct: 296 VTGEQIGYVNAHGTSTPAGDVAEVKGIKRALGEAGTKQVLVSSTKSMTGHLLGAAGSVEA 355 Query: 396 AFTTLACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLC 455 T ++ Q +PPT+NLD E ++ VP A+ K E + NSFGFGGTN +L Sbjct: 356 IITVMSLVDQMVPPTINLDNPEEGLGVDLVPHVAR--KVESMEYAMCNSFGFGGTNGSLI 413 Query: 456 IAGL 459 + Sbjct: 414 FKRM 417 >4JPF-A nrPDB Length = 436 Score = 519 bits (1336), Expect = e-147, Method: Composition-based stats. Identities = 191/423 (45%), Positives = 269/423 (63%), Gaps = 11/423 (2%) Query: 38 SRLHRRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSD 97 S RRVVITG+G+++PLG+ W+ ++ G SGI + + + V Sbjct: 22 SMSRRRVVITGMGMLSPLGLDVPSSWEGILAGRSGIAPIEHMDLSAYSTRFGGSVK---- 77 Query: 98 EGQFNEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPL 157 FN + ++S + + + + A+ A++DSG ++A++ GV++G G+ L Sbjct: 78 --GFNVEEYLSAKEARKLDLFIQYGLAASFQAVRDSGLEV-TDANRERIGVSMGSGIGGL 134 Query: 158 EVVSETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVG 217 + + +G ++SPFFVP ++NM +G +SI L+GPN+A++TACTTG H++G Sbjct: 135 TNIENNCRSLFEQGPRRISPFFVPGSIINMVSGFLSIHLGLQGPNYALTTACTTGTHSIG 194 Query: 218 DSFRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALST-NSDPKLACRPFHPKRDGFVM 276 + R IA+G+ADVMVAGG++ L L GF ARALST N +P A RP+ RDGFV+ Sbjct: 195 MAARNIAYGEADVMVAGGSEMAACGLGLGGFGAARALSTRNDEPTRASRPWDRDRDGFVL 254 Query: 277 GEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAG 336 +G+ LVLEE EHA R ARIYAE++G+G+SGDA H+TAP +G GA RCM AL+DAG Sbjct: 255 SDGSGALVLEELEHARARGARIYAELVGFGMSGDAFHMTAPPEDGAGAARCMKNALRDAG 314 Query: 337 VQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAA 396 + P ++ YINAH TSTP GD AE A+K +F +HA+AL++SSTK TGHLLGAAGAVEA Sbjct: 315 LDPRQVDYINAHGTSTPAGDIAEIAAVKSVFGEHAHALSMSSTKSMTGHLLGAAGAVEAI 374 Query: 397 FTTLACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCI 456 F+ LA Q PPT+NLD + DL+ V +A+ K + + L+NSFGFGGTN TL Sbjct: 375 FSVLALRDQVAPPTINLDNPDEGCDLDLVAHEAKPRKID---VALSNSFGFGGTNGTLVF 431 Query: 457 AGL 459 Sbjct: 432 RRF 434 >4JGA-A nrPDB Length = 437 Score = 517 bits (1331), Expect = e-147, Method: Composition-based stats. Identities = 199/427 (46%), Positives = 274/427 (64%), Gaps = 9/427 (2%) Query: 38 SRLHRRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSD 97 R+++RVVITG+GLVTP+G+ + W ++ G SGI ++ + + C +A + Sbjct: 12 QRVNKRVVITGLGLVTPVGLNVNSSWKNIVDGVSGIKTITEFDTSKLACKIAGLIDNSEK 71 Query: 98 EGQFNEQNFVSKSDIKS---MSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGM 154 +G F +NF DI M + AA A++DSGW P E + TG+ +G G+ Sbjct: 72 DG-FKLENFTQADDINRLSKMDKFIHYGVAAATEAVEDSGWLPDDEKSRDRTGLILGSGI 130 Query: 155 IPLEVVSETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAH 214 L+++ +T++ + KVSPFF+P L+N+ +G VSI+Y GPN TAC+TGAH Sbjct: 131 GGLKMIEDTSIKLYQENNGKVSPFFIPASLINLLSGLVSIKYGFSGPNQTAVTACSTGAH 190 Query: 215 AVGDSFRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALST--NSDPKLACRPFHPKRD 272 A+GD+ R I HG ADVM+AGG ++ ++P+ +AGF ARAL T N +PK A RP+ R Sbjct: 191 AIGDAMRMIKHGYADVMIAGGAEAPVTPVGVAGFVAARALCTKYNDNPKKASRPWDKDRS 250 Query: 273 GFVMGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAAL 332 GFVMGEGA V+VLEEYEHA+ R A++Y EV+GYG +GDA H+TAP PEG GA R M A+ Sbjct: 251 GFVMGEGAGVVVLEEYEHALNRGAKVYGEVIGYGSTGDAYHMTAPHPEGRGAYRAMRDAM 310 Query: 333 KDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGA 392 DA + P+ I YINAH TST LGD E A++ LF + + +SSTK + GHLLGAAG+ Sbjct: 311 LDATITPDMIDYINAHGTSTTLGDGIELAAVQKLFLEANPKVLMSSTKSSIGHLLGAAGS 370 Query: 393 VEAAFTTLACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNA 452 VE F+ LA Q PPTLNLD E +++ V LKA++ K + L+NSFGFGGTNA Sbjct: 371 VEFIFSALAIRDQIAPPTLNLDTPMDEVNIDLVALKAKKTKID---YVLSNSFGFGGTNA 427 Query: 453 TLCIAGL 459 +L I + Sbjct: 428 SLVIKSI 434 >4QAV-A nrPDB Length = 415 Score = 510 bits (1313), Expect = e-145, Method: Composition-based stats. Identities = 192/424 (45%), Positives = 262/424 (61%), Gaps = 14/424 (3%) Query: 39 RLHRRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDE 98 RRVVITG+G V+P+G WD L+ G+SGI ++ + I VA V Sbjct: 1 MSQRRVVITGLGQVSPVGNTVAEAWDTLLAGKSGIGAITRFDASDINSRVAGEVR----- 55 Query: 99 GQFNEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLE 158 F+ ++S + + M I AA A+ DSG D+ GV IG G+ L Sbjct: 56 -GFDIGQYISAKEARRMDVFIHYGIAAALQAIADSGLDDVENLDKDRIGVNIGSGIGGLP 114 Query: 159 VVSETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGD 218 + T G K++PFF+P L+N+ +G V+I +GP++ + +ACTTGAHA+G+ Sbjct: 115 SIEVTGKAVIEGGARKINPFFIPGSLINLISGHVTILKGYRGPSYGMVSACTTGAHAIGN 174 Query: 219 SFRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALST-NSDPKLACRPFHPKRDGFVMG 277 S R I +GDAD+MVAGG + IS L + GF+ +ALST N DP A RP+ RDGFV+G Sbjct: 175 SARLIKYGDADIMVAGGAEGAISTLGVGGFAAMKALSTRNDDPATASRPWDKGRDGFVIG 234 Query: 278 EGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGV 337 EGA +LVLEE EHA +R A+IYAE++G+G+S DA HITAP+ EG + ALKDAG+ Sbjct: 235 EGAGILVLEELEHAKKRGAKIYAEIVGFGMSSDAYHITAPNEEG--PALAVTRALKDAGI 292 Query: 338 QPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAF 397 PE++ Y+NAH TSTPLGDA E KA+K F +HAY VSSTK TGHLLGAAG VEA + Sbjct: 293 NPEDVDYVNAHGTSTPLGDANETKALKRAFGEHAYKTVVSSTKSMTGHLLGAAGGVEAVY 352 Query: 398 TTLACYYQKLPPTLNLDCSEPE--FDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLC 455 + LA + K+PPT+N+ + E DL+Y +A++ + + + ++NSFGFGGTN TL Sbjct: 353 SILAIHDGKIPPTINIFEQDVEAGCDLDYCANEARDAEID---VAISNSFGFGGTNGTLV 409 Query: 456 IAGL 459 Sbjct: 410 FKRF 413 >3KZU-A nrPDB Length = 428 Score = 499 bits (1286), Expect = e-142, Method: Composition-based stats. Identities = 216/421 (51%), Positives = 284/421 (67%), Gaps = 7/421 (1%) Query: 41 HRRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGS-DEG 99 RRVVITG+GLV+PL G W RL+ GESG + E + C +A +P G G Sbjct: 9 MRRVVITGLGLVSPLASGVEETWKRLLAGESGARRVTEFEVDDLACQIACRIPVGDGTNG 68 Query: 100 QFNEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEV 159 FN + + + + + A+GAA+ A+ D+GWHP+++ DQV TGV IG G+ +E Sbjct: 69 TFNPDLHMDPKEQRKVDPFIVYAVGAADQALDDAGWHPENDEDQVRTGVLIGSGIGGIEG 128 Query: 160 VSETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDS 219 + E + KG ++SPFF+P L+N+A+G VSI++KL+GPNH+V TAC TG HA+GD+ Sbjct: 129 IVEAGYTLRDKGPRRISPFFIPGRLINLASGHVSIKHKLRGPNHSVVTACATGTHAIGDA 188 Query: 220 FRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALST--NSDPKLACRPFHPKRDGFVMG 277 R IA GDADVMVAGGT+S +S +SLAGF+ +ALST N DP A RP+ RDGFVMG Sbjct: 189 ARLIAFGDADVMVAGGTESPVSRISLAGFAACKALSTERNDDPTAASRPYDEDRDGFVMG 248 Query: 278 EGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGV 337 EGA ++VLEE EHA+ R A+IYAEV+GYG+SGDA HITAP GEGA RCM AALK AG+ Sbjct: 249 EGAGIVVLEELEHALARGAKIYAEVIGYGMSGDAFHITAPTESGEGAQRCMVAALKRAGI 308 Query: 338 QPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAF 397 P+EI YINAH TST + D E A++ + + A +++SSTK + GHLLGAAGA EA F Sbjct: 309 VPDEIDYINAHGTST-MADTIELGAVERVVGEAAAKISMSSTKSSIGHLLGAAGAAEAVF 367 Query: 398 TTLACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCIA 457 +TLA P TLNLD + ++ VP K +E K + + L+NSFGFGGTNA+L + Sbjct: 368 STLAIRDNIAPATLNLDNPAAQTRIDLVPHKPRERKID---VALSNSFGFGGTNASLVLR 424 Query: 458 G 458 Sbjct: 425 R 425 >3HO9-A nrPDB Length = 427 Score = 498 bits (1282), Expect = e-141, Method: Composition-based stats. Identities = 188/420 (44%), Positives = 267/420 (63%), Gaps = 10/420 (2%) Query: 41 HRRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDEGQ 100 RRVV+TG+G+++P+G W L+ G+SGI + + + A V Sbjct: 17 KRRVVVTGLGMLSPVGNTVESTWKALLAGQSGISLIDHFDTSAYATKFAGLVK------D 70 Query: 101 FNEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVV 160 FN ++ +S+ + + M + I A AM+DSG +E + G AIG G+ L ++ Sbjct: 71 FNCEDIISRKEQRKMDAFIQYGIVAGVQAMQDSGLEI-TEENATRIGAAIGSGIGGLGLI 129 Query: 161 SETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSF 220 E + G K+SPFFVP +VNM AG ++I Y L+GP+ +++TA T+G H +G + Sbjct: 130 EENHTSLMNGGPRKISPFFVPSTIVNMVAGHLTIMYGLRGPSISIATAATSGVHNIGHAA 189 Query: 221 RFIAHGDADVMVAGGTDSCISPLSLAGFSRARALST-NSDPKLACRPFHPKRDGFVMGEG 279 R IA+GDADVMVAGG + +PL + GF ARALST N +P+ A RP+ +RDGFV+G+G Sbjct: 190 RIIAYGDADVMVAGGAEKASTPLGVGGFGAARALSTRNDNPQAASRPWDKERDGFVLGDG 249 Query: 280 AAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGVQP 339 A +LVLEEYEHA +R A+IYAE++G+G+S DA H+T+P G GA MA AL+DAG++ Sbjct: 250 AGMLVLEEYEHAKKRGAKIYAELVGFGMSSDAYHMTSPPENGAGAALAMANALRDAGIEA 309 Query: 340 EEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFTT 399 +I Y+NAH TSTP GD AE +A+K +F + A + VSSTK TGHLLGAAGAVE+ ++ Sbjct: 310 SQIGYVNAHGTSTPAGDKAEAQAVKTIFGEAASRVLVSSTKSMTGHLLGAAGAVESIYSI 369 Query: 400 LACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCIAGL 459 LA Q +PPT+NLD + DL++VP +A++ L NSFGFGGTN +L + Sbjct: 370 LALRDQAVPPTINLDNPDEGCDLDFVPHEARQ--VSGMEYTLCNSFGFGGTNGSLIFKKI 427 >2IX4-A nrPDB Length = 431 Score = 495 bits (1275), Expect = e-140, Method: Composition-based stats. Identities = 221/436 (50%), Positives = 294/436 (67%), Gaps = 23/436 (5%) Query: 42 RRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEE--------------YKSIPCS 87 RRVV+TG+G+VTPLG G W RLI GE GI L ++ + + Sbjct: 1 RRVVVTGLGMVTPLGRGVETTWRRLIDGECGIRGLTLDDLKMKSFDEETKLYTFDQLSSK 60 Query: 88 VAAYVPRGSDEGQFNEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATG 147 VAA+VP GS+ G+F+E +++ +++ A+ AA+ A++D+ W P E ++ TG Sbjct: 61 VAAFVPYGSNPGEFDEALWLNSKA---VANFIGYAVCAADEALRDAEWLPTEEEEKERTG 117 Query: 148 VAIGMGMIPLEVVSETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVST 207 V+IG G+ + + E A K ++SPFF+PKILVNMA+G VS++Y +GPNHA T Sbjct: 118 VSIGGGIGSICDIVEAAQLICEKRLRRLSPFFIPKILVNMASGHVSMKYGFQGPNHAAVT 177 Query: 208 ACTTGAHAVGDSFRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALST--NSDPKLACR 265 AC TGAH++GD+ R I GDADVMVAGGT+S I LS+AGFSR+RALST NS P+ A R Sbjct: 178 ACATGAHSIGDATRMIQFGDADVMVAGGTESSIDALSVAGFSRSRALSTKFNSSPQEASR 237 Query: 266 PFHPKRDGFVMGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGAL 325 PF RDGFV+GEG+ V+VLEEYEHA +R A+IYAE+ GYG+SGDA HIT P +G+GA+ Sbjct: 238 PFDCDRDGFVIGEGSGVIVLEEYEHAKRRGAKIYAELCGYGMSGDAHHITQPPEDGKGAV 297 Query: 326 RCMAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYA--LAVSSTKGAT 383 M AL+ +G+ P +I Y+NAHATSTP+GDA E +AIK +F +HA + LA SSTKGAT Sbjct: 298 LAMTRALRQSGLCPNQIDYVNAHATSTPIGDAVEARAIKTVFSEHATSGTLAFSSTKGAT 357 Query: 384 GHLLGAAGAVEAAFTTLACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTN 443 GHLLGAAGAVEA F+ LA ++ P TLN+ +P FD ++PL K ++N Sbjct: 358 GHLLGAAGAVEAIFSILAIHHGVAPMTLNVKNPDPIFDKRFMPLTTS--KKMLVRTAMSN 415 Query: 444 SFGFGGTNATLCIAGL 459 SFGFGGTNA+L A + Sbjct: 416 SFGFGGTNASLLFASI 431 >3E60-A nrPDB Length = 424 Score = 483 bits (1242), Expect = e-137, Method: Composition-based stats. Identities = 211/422 (50%), Positives = 279/422 (66%), Gaps = 7/422 (1%) Query: 41 HRRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGS-DEG 99 RRVVITG+GLV+PL W RL+ G+SG+ + + + C +AA +P G G Sbjct: 5 MRRVVITGLGLVSPLAGDVEYSWKRLLEGKSGVRRITEFDVSDLSCQIAARIPVGDGTNG 64 Query: 100 QFNEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEV 159 +N + + + + + + AI AA+ A+ D+ W P+S+ DQ+ TGV IG G+ +E Sbjct: 65 TYNADLHMESKEQRKVDAFIVYAIAAADQALADAEWFPKSDEDQICTGVLIGSGIGGIEG 124 Query: 160 VSETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDS 219 + E + KG ++SPFF+P L+N+A+G VSI+Y L+GPNH+V TAC+TGAHA+GD+ Sbjct: 125 IVEAGYTLRDKGPRRISPFFIPGRLINLASGYVSIKYGLRGPNHSVVTACSTGAHAIGDA 184 Query: 220 FRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALST--NSDPKLACRPFHPKRDGFVMG 277 R IA GDADVM+AGGT+S I+ +SLAGFS RALST N DP+ A RP+ RDGFVMG Sbjct: 185 ARLIALGDADVMLAGGTESPINRISLAGFSACRALSTCRNDDPERASRPYDVDRDGFVMG 244 Query: 278 EGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGV 337 EGAA++VLEE EHA +R ARIYAE++GYGLSGDA HITAP GEGA R M AALK A V Sbjct: 245 EGAAIVVLEELEHAKKRGARIYAEIIGYGLSGDAYHITAPSESGEGAQRSMMAALKRAQV 304 Query: 338 QPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAF 397 E+ YINAH TST + D E A++ + +A +++SSTK + GHLLGAAGA EA F Sbjct: 305 NVSELDYINAHGTST-MADVIELAAVERVLGYYAPQVSMSSTKSSIGHLLGAAGAAEAIF 363 Query: 398 TTLACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCIA 457 LA P TLNL+ E ++ VP K +E K + L+NSFGFGGTNA+L + Sbjct: 364 CVLAIRDNIAPATLNLENPSIETKIDLVPHKPRERKID---TVLSNSFGFGGTNASLVMR 420 Query: 458 GL 459 Sbjct: 421 RF 422 >1OXH-A nrPDB Length = 430 Score = 481 bits (1238), Expect = e-136, Method: Composition-based stats. Identities = 158/428 (36%), Positives = 236/428 (55%), Gaps = 15/428 (3%) Query: 33 GTVPISRLHR--RVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAA 90 G VP + RVV+TG G+ +P+G W+ L G+ GI + ++ AA Sbjct: 12 GLVPRGSHMKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHSDFDVHNAA 71 Query: 91 YVPRGSDEGQFNEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAI 150 + F + K D + ++ A+ AA+ A+ + ++ ++ GV + Sbjct: 72 EIQ------DFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEA-LNRDRFGVIV 124 Query: 151 GMGMIPLEVVSETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACT 210 G+ ++ + + L KG +V P +PK L NMA+G V++R+ G +++TAC+ Sbjct: 125 ASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSINTACS 184 Query: 211 TGAHAVGDSFRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALSTNSDPKLACRPFHPK 270 + A+GD+FR I G DVM+ GGT++ I+P ++AGF ALST DP A PF Sbjct: 185 SSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRASIPFDKD 244 Query: 271 RDGFVMGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAA 330 R+GFVMGEG+ +LVLE EHA +R A I AEV+GYG + DA H+T+P PEG+GA++ + Sbjct: 245 RNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEGQGAIKAIKL 304 Query: 331 ALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAA 390 AL++A + PE+++Y+NAH TSTP + E+ AI + + VSSTK TGHLLGAA Sbjct: 305 ALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKE---VPVSSTKSFTGHLLGAA 361 Query: 391 GAVEAAFTTLACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGT 450 GAVEA T A + +P T + N V Q + E ++N+FGFGG Sbjct: 362 GAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVV--YGQGLEKEIP-YAISNTFGFGGH 418 Query: 451 NATLCIAG 458 NA L Sbjct: 419 NAVLAFKR 426 >4DDO-A nrPDB Length = 451 Score = 451 bits (1159), Expect = e-127, Method: Composition-based stats. Identities = 186/421 (44%), Positives = 261/421 (61%), Gaps = 9/421 (2%) Query: 43 RVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRG--SDEGQ 100 RVV+TGIG+V+PLG G LVW RLIGG SG+ L + + V V EG Sbjct: 25 RVVVTGIGIVSPLGCGKELVWQRLIGGGSGLRRLGDDIAGELSAKVGGTVQDVAEDPEGG 84 Query: 101 FNEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVV 160 F+ + V +++ M MA+ AA+ A+ ++GW P++E + T + G+ + Sbjct: 85 FDPERSVPHKELRKMDRFIQMAMVAADEALAEAGWAPEAEQQRERTATVVASGIGGFPGL 144 Query: 161 SETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSF 220 +E +T+G ++SPF +P L N+AAGQ+SI+++ +GP TAC A+GD+ Sbjct: 145 AEAVRIGETRGVRRLSPFTIPFFLSNLAAGQISIKHRFRGPLGCPVTACAASVQAIGDAM 204 Query: 221 RFIAHGDADVMVAGGTDSCISPLSLAGFSRARALST--NSDPKLACRPFHPKRDGFVMGE 278 R I G+ADV++AGG ++ +SL GF+ ARALST + +P A RPF RDGFVMGE Sbjct: 205 RMIRTGEADVVLAGGAEAAFDKVSLGGFAAARALSTGFSEEPVRASRPFDRDRDGFVMGE 264 Query: 279 GAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGVQ 338 GAA++V+E +HA+ R AR AE++GYG + DA H+TA +G GA+R M AL+ V Sbjct: 265 GAAMVVVESLDHALARGARPIAEIIGYGTTADAYHMTAGPDDGSGAMRAMKLALRMGDVA 324 Query: 339 PEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFT 398 PE++ Y+NAHATSTP+GDA E +A+K +F A A+SSTK ATGHLLGAAGA+EAAF+ Sbjct: 325 PEQVDYVNAHATSTPVGDAGEIEALKTVFGVGA-GPAISSTKSATGHLLGAAGAIEAAFS 383 Query: 399 TLACYYQKLPPTLNLDCSEPEFD-LNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCIA 457 LA LP TLNL+ +P D L+ + A+ E I L+N FGFGG NA++ Sbjct: 384 ILALRDGVLPGTLNLEHPDPAADGLDLIGPAARHVPVE---IALSNGFGFGGVNASVLFR 440 Query: 458 G 458 Sbjct: 441 R 441 >4XOX-A nrPDB Length = 404 Score = 445 bits (1144), Expect = e-125, Method: Composition-based stats. Identities = 140/421 (33%), Positives = 227/421 (53%), Gaps = 24/421 (5%) Query: 41 HRRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDEGQ 100 +RVVITG+G+++ +G V L G+SGI + + + V + + Sbjct: 1 MKRVVITGMGIISSIGNNVEEVLASLKAGKSGITASEQFKEHGLRSQVWG-------DLK 53 Query: 101 FNEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVV 160 N + + + ++ M A + E A+ D+G P+ ++ TG+ G G E Sbjct: 54 INPEEHIDRKQMRFMGDAAAYAYLSLEQAIADAGLTPEQVSN-DRTGIVAGSGGASSENQ 112 Query: 161 SETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSF 220 + KG +V P+ VP+ + + + ++ +K++G N+++S+AC T AH +G++ Sbjct: 113 VIAVDTQREKGVKRVGPYMVPRTMSSTVSACLATPFKIRGVNYSISSACATSAHCIGNAV 172 Query: 221 RFIAHGDADVMVAGGTDSCISPLSLAGFSRARALST--NSDPKLACRPFHPKRDGFVMGE 278 I G D++ AGG + ++ F ALST N P+ A R + RDGFV+ Sbjct: 173 ELIQLGKQDIVFAGGGEELYWSQTMM-FDAMGALSTKYNETPEKASRTYDADRDGFVISG 231 Query: 279 GAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGVQ 338 G ++V+EE EHA+ R A+IY E++GYG + D + AP GEGA+RCM A++ Sbjct: 232 GGGMVVVEELEHALARGAKIYGEIVGYGATSDGYDMVAPS--GEGAIRCMKMAMQ----G 285 Query: 339 PEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFT 398 ++I YIN H TSTP+GD E AI+ +F ++ A+S+TK TGH LGAAG EA ++ Sbjct: 286 VDKIDYINTHGTSTPVGDVKELGAIQEVFGGNSP--AISATKAMTGHALGAAGVHEAIYS 343 Query: 399 TLACYYQKLPPTLNLDCSEP-EFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCIA 457 TL ++ + P++N+D + L+ V E + ++ ++NSFGFGGTNATL I Sbjct: 344 TLMLHHGFIAPSINIDTLDEAAQGLDIVT----ELREQELTTVMSNSFGFGGTNATLVIK 399 Query: 458 G 458 Sbjct: 400 K 400 >3U0E-A nrPDB Length = 428 Score = 428 bits (1100), Expect = e-120, Method: Composition-based stats. Identities = 143/420 (34%), Positives = 216/420 (51%), Gaps = 18/420 (4%) Query: 41 HRRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDEGQ 100 RRVV+TG+G+V+ +G T V L +SGI C V Sbjct: 22 MRRVVVTGMGIVSSIGSNTEEVTASLREAKSGISRAEEYAELGFRCQVHG-------APD 74 Query: 101 FNEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVV 160 + ++ V + ++ T A + A+ D+G + E TG+ +G G + Sbjct: 75 IDIESLVDRRAMRFHGRGTAWNHIAMDQAIADAGLT-EEEVSNERTGIIMGSGGPSTRTI 133 Query: 161 SETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSF 220 ++A + KG +V PF VPK + + A+ ++ +K+KG N+++S+AC T H +G+++ Sbjct: 134 VDSADITREKGPKRVGPFAVPKAMSSTASATLATFFKIKGINYSISSACATSNHCIGNAY 193 Query: 221 RFIAHGDADVMVAGGTDSCISPLSLAGFSRARALST--NSDPKLACRPFHPKRDGFVMGE 278 I +G D M AGG + LS+ F A+S+ N P A R + RDGFV+ Sbjct: 194 EMIQYGKQDRMFAGGCEDLDWTLSVL-FDAMGAMSSKYNDTPSTASRAYDKNRDGFVIAG 252 Query: 279 GAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGVQ 338 GA VLVLE+ E A+ R A+IY E++GYG + D + AP GEGA+RCM AL Sbjct: 253 GAGVLVLEDLETALARGAKIYGEIVGYGATSDGYDMVAPS--GEGAIRCMKMALSTV--- 307 Query: 339 PEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFT 398 +I YIN HATSTP GDA E +AI+ +F +++TK TGH LGA G EA ++ Sbjct: 308 TSKIDYINPHATSTPAGDAPEIEAIRQIFGAGDVCPPIAATKSLTGHSLGATGVQEAIYS 367 Query: 399 TLACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCIAG 458 L + + +++ +P F +P+ + + L+NSFGFGGTNATL Sbjct: 368 LLMMQNNFICESAHIEELDPAF--ADMPIVRKRIDNVQLNTVLSNSFGFGGTNATLVFQR 425 >3OYT-A nrPDB Length = 410 Score = 427 bits (1097), Expect = e-120, Method: Composition-based stats. Identities = 146/424 (34%), Positives = 220/424 (51%), Gaps = 20/424 (4%) Query: 38 SRLHRRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSD 97 S +R VITG+G+V+ +G V L G SGI + + V V S+ Sbjct: 1 SNAMKRAVITGLGIVSSIGNNQQEVLASLQEGRSGITFAQEFKDAGMRSHVWGDVKLQSE 60 Query: 98 EGQFNEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPL 157 ++ + + ++ MS +I A A + A+ DSG ++ + V G P Sbjct: 61 -----PKDLIDRKVLRFMSDASIYAYLAMQEAIADSGLSDSQVSNFRSGLVVGSGGGSPR 115 Query: 158 EVVSETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVG 217 V+ + +G V P+ V K + + + ++ +K+KG N+++S+AC T AH +G Sbjct: 116 NQVAGSDAMRTPRGLKGVGPYMVTKAMASGVSACLATPFKIKGVNYSISSACATSAHCIG 175 Query: 218 DSFRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALST--NSDPKLACRPFHPKRDGFV 275 + I G D++ AGG + ++ F ALST N P A R + RDGFV Sbjct: 176 HALELIQLGKQDIVFAGGGEELCWEMACE-FDAMGALSTKYNDTPAKASRTYDQDRDGFV 234 Query: 276 MGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDA 335 + G ++V+EE EHA+ R A IYAE++GYG + D + AP GEGA+RCM A+ A Sbjct: 235 IAGGGGMVVVEELEHALARGAHIYAEIVGYGATSDGADMVAPS--GEGAVRCMQMAM--A 290 Query: 336 GVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEA 395 GV I Y+N H TSTP+GD E AI+ +F ++ A+SSTK TGH LGAAG EA Sbjct: 291 GVDT-PIDYMNVHGTSTPVGDVKELGAIREVFGNNTP--AISSTKAMTGHSLGAAGVHEA 347 Query: 396 AFTTLACYYQKLPPTLNLDCSEPE-FDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATL 454 F+ L + + P++N+D + + +N + Q T ++NSFGFGGTNATL Sbjct: 348 IFSLLMVEHGFIAPSINIDNLDEQAQGMNIITETTQRELTT----VMSNSFGFGGTNATL 403 Query: 455 CIAG 458 + Sbjct: 404 VMRK 407 >2BZ4-A nrPDB Length = 418 Score = 424 bits (1091), Expect = e-119, Method: Composition-based stats. Identities = 141/423 (33%), Positives = 219/423 (51%), Gaps = 23/423 (5%) Query: 41 HRRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDEGQ 100 +R VITG+G+V+ +G V L G SGI + + V V + Sbjct: 13 MKRAVITGLGIVSSIGNNQQEVLASLREGRSGITFSQELKDSGMRSHVWGNV-------K 65 Query: 101 FNEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVV 160 + + + ++ MS +I A + E A+ D+G P++ + G+ G G Sbjct: 66 LDTTGLIDRKVVRFMSDASIYAFLSMEQAIADAGLSPEAYQNNPRVGLIAGSGGGSPRFQ 125 Query: 161 SETALNFQ-TKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDS 219 A + +G V P+ V K + + + ++ +K+ G N+++S+AC T AH +G++ Sbjct: 126 VFGADAMRGPRGLKAVGPYVVTKAMASGVSACLATPFKIHGVNYSISSACATSAHCIGNA 185 Query: 220 FRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALST--NSDPKLACRPFHPKRDGFVMG 277 I G D++ AGG + ++ F ALST N P+ A R + RDGFV+ Sbjct: 186 VEQIQLGKQDIVFAGGGEELCWEMACE-FDAMGALSTKYNDTPEKASRTYDAHRDGFVIA 244 Query: 278 EGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGV 337 G ++V+EE EHA+ R A IYAE++GYG + D + AP GEGA+RCM A+ GV Sbjct: 245 GGGGMVVVEELEHALARGAHIYAEIVGYGATSDGADMVAPS--GEGAVRCMKMAMH--GV 300 Query: 338 QPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAF 397 I Y+N+ TSTP+GD E AI+ +F D + A+S+TK TGH LGAAG EA + Sbjct: 301 DT-PIDYLNSQGTSTPVGDVKELAAIREVFGDKSP--AISATKAMTGHSLGAAGVQEAIY 357 Query: 398 TTLACYYQKLPPTLNLDCSEPE-FDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCI 456 + L + + P++N++ + + LN V E + ++NSFGFGGTNATL + Sbjct: 358 SLLMLEHGFIAPSINIEELDEQAAGLNIVT----ETTDRELTTVMSNSFGFGGTNATLVM 413 Query: 457 AGL 459 L Sbjct: 414 RKL 416 >1TQY-A nrPDB Length = 424 Score = 417 bits (1072), Expect = e-117, Method: Composition-based stats. Identities = 147/431 (34%), Positives = 210/431 (48%), Gaps = 29/431 (6%) Query: 40 LHRRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDEG 99 + RRVVITG+G+ P G GT W+ L G + + + VAA Sbjct: 1 MKRRVVITGVGVRAPGGNGTRQFWELLTSGRTATRRISFFDPSPYRSQVAAE-------A 53 Query: 100 QFNE--QNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPL 157 F+ + F + ++ M + A+ A A SG P + D GV++G + Sbjct: 54 DFDPVAEGFGPR-ELDRMDRASQFAVACAREAFAASGLDPDT-LDPARVGVSLGSAVAAA 111 Query: 158 EVVSETALNFQTKGY----------NKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVST 207 + L G + + VP ++ +V+ +GP VST Sbjct: 112 TSLEREYLLLSDSGRDWEVDAAWLSRHMFDYLVPSVMP----AEVAWAVGAEGPVTMVST 167 Query: 208 ACTTGAHAVGDSFRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALST-NSDPKLACRP 266 CT+G +VG++ R I G ADVM AG D+ I+P+ +A F RA + N DP+ A RP Sbjct: 168 GCTSGLDSVGNAVRAIEEGSADVMFAGAADTPITPIVVACFDAIRATTARNDDPEHASRP 227 Query: 267 FHPKRDGFVMGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALR 326 F RDGFV+ EGAA+ VLE+Y+ A+ R ARI+AE+ GY +A H+T +G Sbjct: 228 FDGTRDGFVLAEGAAMFVLEDYDSALARGARIHAEISGYATRCNAYHMTGLKADGREMAE 287 Query: 327 CMAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHL 386 + AL ++ +I YINAH + T D E A K +HA VSS K GH Sbjct: 288 TIRVALDESRTDATDIDYINAHGSGTRQNDRHETAAYKRALGEHARRTPVSSIKSMVGHS 347 Query: 387 LGAAGAVEAAFTTLACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFG 446 LGA G++E A LA + +PPT NL S+PE DL+YVPL+A+E K LT G Sbjct: 348 LGAIGSLEIAACVLALEHGVVPPTANLRTSDPECDLDYVPLEARERKL---RSVLTVGSG 404 Query: 447 FGGTNATLCIA 457 FGG + + + Sbjct: 405 FGGFQSAMVLR 415 >2GP6-A nrPDB Length = 434 Score = 409 bits (1051), Expect = e-114, Method: Composition-based stats. Identities = 143/417 (34%), Positives = 219/417 (52%), Gaps = 19/417 (4%) Query: 44 VVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYK--SIPCSVAAYVPRGSDEGQF 101 VV+TGI + T L W L+ +SGI +L + +P + ++ +F Sbjct: 30 VVVTGIAMTTALATDAETTWKLLLDRQSGIRTLDDPFVEEFDLPVRIGGHLLE-----EF 84 Query: 102 NEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVVS 161 + Q +++ +++ M M+ + +++G E D V+IG G+ E + Sbjct: 85 DHQ--LTRIELRRMGYLQRMSTVLSRRLWENAG---SPEVDTNRLMVSIGTGLGSAEELV 139 Query: 162 ETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSFR 221 + + + +G VSP V K + N AA V + K +AC +GA A+ +++ Sbjct: 140 FSYDDMRARGMKAVSPLTVQKYMPNGAAAAVGLERHAKAGVMTPVSACASGAEAIARAWQ 199 Query: 222 FIAHGDADVMVAGGTDSCISPLSLAGFSRARAL--STNSDPKLACRPFHPKRDGFVMGEG 279 I G+AD + GG ++ I + +AGF++ R + + N DP ACRPF RDGFV GEG Sbjct: 200 QIVLGEADAAICGGVETRIEAVPIAGFAQMRIVMSTNNDDPAGACRPFDRDRDGFVFGEG 259 Query: 280 AAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGVQP 339 A+L++E EHA R A I A ++G ++ D H+ APDP GE A + A++ AG+ P Sbjct: 260 GALLLIETEEHAKARGANILARIMGASITSDGFHMVAPDPNGERAGHAITRAIQLAGLAP 319 Query: 340 EEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFTT 399 +I ++NAHAT T +GD AE +AI + + AV + K A GH +GA GAVE+ T Sbjct: 320 GDIDHVNAHATGTQVGDLAEGRAINNALGGN--RPAVYAPKSALGHSVGAVGAVESILTV 377 Query: 400 LACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCI 456 LA Q +PPTLNL +PE DL+ V A E + + NSFGFGG N + Sbjct: 378 LALRDQVIPPTLNLVNLDPEIDLDVV---AGEPRPGNYRYAINNSFGFGGHNVAIAF 431 >5W2O-A nrPDB Length = 439 Score = 406 bits (1044), Expect = e-113, Method: Composition-based stats. Identities = 141/406 (34%), Positives = 205/406 (50%), Gaps = 19/406 (4%) Query: 54 PLGVGTHLVWDRLIGGESGIVSLVGEEYK--SIPCSVAAYVPRGSDEGQFNEQNFVSKSD 111 + W L+ GESGI +L E + + ++ + + + D Sbjct: 47 SISPDIESTWKGLLAGESGIHALEDEFVTKWDLAVKIGGHLKD-------PVDSHMGRLD 99 Query: 112 IKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVVSETALNFQTKG 171 ++ MS M + +G E D V +G G+ E + E+ G Sbjct: 100 MRRMSYVQRMGKLLGGQLWESAG---SPEVDPDRFAVVVGTGLGGAERIVESYDLMNAGG 156 Query: 172 YNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSFRFIAHGDADVM 231 KVSP V I+ N AA + ++ + +AC++G+ A+ ++R I GDADV Sbjct: 157 PRKVSPLAVQMIMPNGAAAVIGLQLGARAGVMTPVSACSSGSEAIAHAWRQIVMGDADVA 216 Query: 232 VAGGTDSCISPLSLAGFSRARALST-NSDPKLACRPFHPKRDGFVMGEGAAVLVLEEYEH 290 V GG + I L +A FS RA+ST N +P+ A RPF RDGFV GE A++++E EH Sbjct: 217 VCGGVEGPIEALPIAAFSMMRAMSTRNDEPERASRPFDKDRDGFVFGEAGALMLIETEEH 276 Query: 291 AVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGVQPEEISYINAHAT 350 A R A+ A +LG G++ DA H+ AP +G A R M +L+ AG+ P +I ++NAH T Sbjct: 277 AKARGAKPLARLLGAGITSDAFHMVAPAADGVRAGRAMTRSLELAGLSPADIDHVNAHGT 336 Query: 351 STPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFTTLACYYQKLPPT 410 +TP+GDAAE AI+ D A AV + K A GH +GA GA+E+ T L +PPT Sbjct: 337 ATPIGDAAEANAIRVAGCDQA---AVYAPKSALGHSIGAVGALESVLTVLTLRDGVIPPT 393 Query: 411 LNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCI 456 LN + +PE DL+ V A E + + NSFGFGG N L Sbjct: 394 LNYETPDPEIDLDVV---AGEPRYGDYRYAVNNSFGFGGHNVALAF 436 >1TQY-B nrPDB Length = 415 Score = 362 bits (929), Expect = e-100, Method: Composition-based stats. Identities = 107/422 (25%), Positives = 179/422 (42%), Gaps = 23/422 (5%) Query: 42 RRVVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDEGQF 101 + V+ITG+G+V P G+G W ++ G G+ + + P ++A + F Sbjct: 9 KSVLITGVGVVAPNGLGLAPYWSAVLDGRHGLGPVTRFDVSRYPATLAGQI------DDF 62 Query: 102 NEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVVS 161 + + + + T +A+ AA+ A++D+ P+S D GV + Sbjct: 63 HAPDHIPGRLLPQTDPSTRLALTAADWALQDAKADPESLTDY-DMGVVTANACGGFDFTH 121 Query: 162 ETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSFR 221 ++G VS + + GQ+SIR+ ++GP+ A+ G A+G + R Sbjct: 122 REFRKLWSEGPKSVSVYESFAWFYAVNTGQISIRHGMRGPSSALVAEQAGGLDALGHARR 181 Query: 222 FIAHGDADVMVAGGTDSCISPLSLAGFSRARALSTNSDPKLACRPFHPKRDGFVMGEGAA 281 I G ++V+GG DS + P + +ST +DP A PF + G+V GEG A Sbjct: 182 TIRRG-TPLVVSGGVDSALDPWGWVSQIASGRISTATDPDRAYLPFDERAAGYVPGEGGA 240 Query: 282 VLVLEEYEHAVQRR-ARIYAEVLGYGLSGDAGHITAPDP---EGEGALRCMAAALKDAGV 337 +LVLE+ A R Y E+ G + D P P G R + AL DAG Sbjct: 241 ILVLEDSAAAEARGRHDAYGELAGCASTFD------PAPGSGRPAGLERAIRLALNDAGT 294 Query: 338 QPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAF 397 PE++ + A P DAAE +AI +F + V+ K TG L G ++ Sbjct: 295 GPEDVDVVFADGAGVPELDAAEARAIGRVFGREG--VPVTVPKTTTGRLYSGGGPLDVVT 352 Query: 398 TTLACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCIA 457 ++ + PT + E+ ++ V E ++ L + G G N+ + Sbjct: 353 ALMSLREGVIAPTAGVTSVPREYGIDLV---LGEPRSTAPRTALVLARGRWGFNSAAVLR 409 Query: 458 GL 459 Sbjct: 410 RF 411 >5ENY-A nrPDB Length = 764 Score = 333 bits (855), Expect = 8e-92, Method: Composition-based stats. Identities = 114/454 (25%), Positives = 185/454 (40%), Gaps = 56/454 (12%) Query: 34 TVPI--SRLHRRVVITGIGLVTPLGVGTHLVWDRLIGGESGIV--SLVGEEYKSIPCSVA 89 TVP+ R + I G+ P WD L+ + I + Sbjct: 166 TVPVLQDRPEDAIAIVGMSGRYPGARNVREYWDNLVHARNAIRDIPTSRWDVDKY----- 220 Query: 90 AYVPRGSDEGQFNEQNFVSKSDIKSMSSPTIMAIGAAE----------------LAMKDS 133 Y P + +G+ ++ DI+ P I +E A +D+ Sbjct: 221 -YDPVLNKKGKVYCKSMGMLDDIEHFD-PLFFNIPPSEAELMDPQHRIFLQEGYKAFEDA 278 Query: 134 GWHPQSEADQVATGVAIGMGMIPLEVVSETALNFQTKGYNKVSPFFVPKILVNMAAGQVS 193 G++ ++ ++ GV +G+ V+ LN Q++ + F + AA ++ Sbjct: 279 GYNART-LNEKKCGVYLGIMSNEYGVM----LNRQSRANATGNSFAI-------AAARIP 326 Query: 194 IRYKLKGPNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDSCISPLSLAGFSRARA 253 LKGP + TAC++ + + + + + D+ + GG ++P S A Sbjct: 327 YFLNLKGPAIPIDTACSSSLVGTHLARQALINKEIDMALVGGVSLYLTPESYMSMCEAGM 386 Query: 254 LSTNSDPKLACRPFHPKRDGFVMGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDA-- 311 LS P C+ F +GFV GEGA LVL+ + A R IY ++G G++ D Sbjct: 387 LS----PDGQCKAFDNGANGFVPGEGAGALVLKRLKDAEADRDHIYGIIIGSGINQDGKT 442 Query: 312 GHITAPDPEGEGALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHA 371 ITAP + + L + G+ PE ISY+ H T T GD E +A+ +F++ Sbjct: 443 NGITAPSAKSQMDLE--RDIYETYGIHPESISYVEMHGTGTKQGDPIELEALSTVFQEKT 500 Query: 372 ---YALAVSSTKGATGHLLGAAGAVEAAFTTLACYYQKLPPTLNLDCSEPEFDLNYVPL- 427 A+ S K GH AAG L ++ L PTLN F+ + PL Sbjct: 501 DKKQFCAIGSVKSNIGHTSAAAGVAGVQKVLLCMNHKTLVPTLNFTTPNEHFEFEHSPLY 560 Query: 428 ---KAQEWKTE--KRFIGLTNSFGFGGTNATLCI 456 + + W+T K +SFG+ GTNA + I Sbjct: 561 VNTELKPWETADGKPRRACVSSFGYSGTNAHIVI 594 >4OQJ-A nrPDB Length = 845 Score = 292 bits (747), Expect = 2e-79, Method: Composition-based stats. Identities = 105/439 (23%), Positives = 173/439 (39%), Gaps = 40/439 (9%) Query: 44 VVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPC--------SVAAYVPRG 95 + + G+ P W L G + EE ++ Sbjct: 23 IAVIGLACRFPGAATPDTFWKVLSEGRETLTHFSDEELRAAGVAEPLLADDRYVKAGQVL 82 Query: 96 SDEGQFNEQNF-VSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGM 154 D +F+ F +++ + + + + A A++ +G+ PQ ++ +G+ Sbjct: 83 VDADKFDAGLFGITRDEAELIDPQQRQFLECAYEALERAGYDPQRGEQRIGVYAGVGLNT 142 Query: 155 IPLEVVSETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLK----GPNHAVSTACT 210 L + E S ++++ V+ R K GP+ + +TAC+ Sbjct: 143 YLLHNLGERY--------RTASSVDRYRMMITNDKDFVATRTAYKLNLCGPSVSTNTACS 194 Query: 211 TGAHAVGDSFRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALSTNSDPKLACRPFHPK 270 T AV + + GD + +AG + I G+ + + D CR F K Sbjct: 195 TSLVAVHLACLSLLSGDCTMALAGA--AHIQADQGEGYLHHEGMIFSPDGH--CRAFDAK 250 Query: 271 RDGFVMGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGH---ITAPDPEGEGALRC 327 G V+G G +VL+ A+ ++A + G ++ D TAP +G+ A+ Sbjct: 251 AQGTVIGNGVGAVVLKRLSDALADGDTVHAVIKGTAVNNDGSDKTGYTAPSVQGQAAVVA 310 Query: 328 MAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYAL-----AVSSTKGA 382 A + D G PE +SY+ AH T+TPLGD E A+ F AL A+ S K Sbjct: 311 EAQEIADVG--PETVSYVEAHGTATPLGDPIEVAALNQAFNREGAALAPGSCALGSVKTN 368 Query: 383 TGHLLGAAGAVEAAFTTLACYYQKLPPTLNLDCSEPEFDLN----YVPLKAQEWKTEK-R 437 GHL AAG T L ++ L P+L + PE D YV + +EW Sbjct: 369 VGHLDTAAGMAGLIKTILMLRHRTLVPSLCFEAPNPEIDFAAGPFYVGTETKEWPAGPTP 428 Query: 438 FIGLTNSFGFGGTNATLCI 456 +SFG GGTNA + + Sbjct: 429 RRAGVSSFGIGGTNAHVIV 447 >6QSP-A nrPDB Length = 406 Score = 275 bits (703), Expect = 3e-74, Method: Composition-based stats. Identities = 108/414 (26%), Positives = 174/414 (42%), Gaps = 28/414 (6%) Query: 44 VVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDEGQFNE 103 + I+ +G++ LG + L+ G++ S + G + Sbjct: 17 IYISAVGMLNALGDNVDDIAQNLVLGQA---------PGMYERSGWLQPGKTCCLGGVDA 67 Query: 104 QNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVVSET 163 + + +S + AA + +K + + V +G L+ + Sbjct: 68 ELPAMPDMLSEHNSRNNRLLLAALMQIKPQVDEAIARHGRERIAVIMGTSTSGLDEGDQH 127 Query: 164 A-LNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSFRF 222 + + + + + + ++ ++GP +STAC++ + A+ R Sbjct: 128 VSRTVYQQSHGSYHDYHYYQQELGDPSRFLARYLAIEGPAFTLSTACSSSSRAIISGQRL 187 Query: 223 IAHGDADVMVAGGTDSCISPLSLAGFSRARALSTNSDPKLACRPFHPKRDGFVMGEGAAV 282 I G D + GG D+ +S + + GF +LS P L C PF R G +GE + + Sbjct: 188 IEMGLVDAAIVGGADT-LSRMPINGFDSLESLS----PTL-CEPFCQDRQGITIGEASTL 241 Query: 283 LVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGVQPEEI 342 L+L + +LG G S DA H++AP PEG GA+ + AL+ AG+ P EI Sbjct: 242 LLLTREPQPIA--------LLGVGESSDAWHMSAPHPEGRGAIAAINMALRKAGISPAEI 293 Query: 343 SYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFTTLAC 402 YIN H T T L D E+ I +F ++ SSTK TGH LGAAGA EA L Sbjct: 294 GYINLHGTGTKLNDQMESIVINQIFGENT---PCSSTKYLTGHTLGAAGACEAGLCWLLL 350 Query: 403 YYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCI 456 P + S + L L Q EK + ++NSF FGG N +L + Sbjct: 351 TRHLPLPAQDFTRSGIDIALPACGLLTQSQPLEKPIV-MSNSFAFGGNNTSLIL 403 >4CW4-A nrPDB Length = 639 Score = 257 bits (657), Expect = 7e-69, Method: Composition-based stats. Identities = 88/401 (21%), Positives = 165/401 (41%), Gaps = 34/401 (8%) Query: 81 YKSIPCSVAAYVPRGSDEGQFNEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSE 140 Y+++ A +P G + G+ + + M++ AA A++ +G ++ Sbjct: 162 YRALTVKSAGQLPTGFEPGELY--------NSRFHPRGLQMSVVAATDAIRSTGIDWKTI 213 Query: 141 ADQVA---TGVAIGMGMIPLEVVSETALNFQTKGYNKVSPFFVPKILVNMAAGQV-SIRY 196 D V V G M L+ L ++VS +P +M + + Sbjct: 214 VDNVQPDEIAVFSGSIMSQLDDNGFGGLMQSRLKGHRVSAKQLPLGFNSMPTDFINAYVL 273 Query: 197 KLKGPNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALST 256 G +++ AC T + + I G A V++ G +++ I P + G+S AL+T Sbjct: 274 GSVGMTGSITGACATFLYNLQKGIDVITSGQARVVIVGNSEAPILPECIEGYSAMGALAT 333 Query: 257 -----------NSDPKLACRPFHPKRDGFVMGEGAAVLVLEEYEHAVQRRARIYAEVLGY 305 + D + A RPF GF + E + +VL + E A++ A I+ V Sbjct: 334 EEGLRLIEGRDDVDFRRASRPFGE-NCGFTLAESSQYVVLMDDELALRLGADIHGAVTDV 392 Query: 306 GLSGDAG--HITAPDPEGEGAL-RCMAAALKDAGVQP-EEISYINAHATSTPLGDAAENK 361 ++ D I+AP P + + +A+A++ G+ S+++AH +STP E++ Sbjct: 393 FINADGFKKSISAPGPGNYLTVAKAVASAVQIVGLDTVRHASFVHAHGSSTPANRVTESE 452 Query: 362 AIKHL---FKDHAYALAVSSTKGATGHLLGAAGAVEAAFTTLACYYQKLPPTLNLDCSEP 418 + + F + V++ K GH L A A + Y LP +D Sbjct: 453 ILDRVASAFGIDGW--PVTAVKAYVGHSLATASADQLISALGTFKYGILPGIKTIDKVAD 510 Query: 419 EFDLNYVPLKAQEWKTEKRF-IGLTNSFGFGGTNATLCIAG 458 + + + ++ + +K + NS GFGG NA+ + Sbjct: 511 DVHQQRLSISNRDMRQDKPLEVCFINSKGFGGNNASGVVLS 551 >4E1L-A nrPDB Length = 395 Score = 103 bits (257), Expect = 2e-22, Method: Composition-based stats. Identities = 42/144 (29%), Positives = 65/144 (45%), Gaps = 19/144 (13%) Query: 270 KRDGFV-------MGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGE 322 K+DG V + +GAA+L+L + A + R A++ Y +G P+ G Sbjct: 240 KKDGTVTAGNASGINDGAAMLILMSQQKADELGIRPLAKIKSYASAG-----VEPEVMGT 294 Query: 323 GALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGA 382 G + ALK AG+ +I I A+ AA+ A+K+ + + L V+ A Sbjct: 295 GPIPATRKALKKAGLSINDIDLIEANEAF-----AAQALAVKNELQIDSSKLNVNGGAIA 349 Query: 383 TGHLLGAAGAVEAAFTTLACYYQK 406 GH +GA+GA TL QK Sbjct: 350 LGHPIGASGA--RILVTLIYEMQK 371 Score = 43.9 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 25/122 (20%), Positives = 46/122 (37%), Gaps = 33/122 (27%) Query: 118 PTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVVSETALNFQTKGYNKVSP 177 + A + A+ G + SE D+V G + G+ Sbjct: 29 AVQLGTIAVKEAISRVGLNL-SEIDEVIIGNVLQTGLG---------------------- 65 Query: 178 FFVPKILVNMAAGQVSIRYKLKG--PNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGG 235 A Q++I + P++ V+ C +G +V + + I G+ DV++AGG Sbjct: 66 --------QNVARQIAINAGIPNSVPSYTVNKLCGSGLKSVQLAAQSITSGENDVVIAGG 117 Query: 236 TD 237 T+ Sbjct: 118 TE 119 >4DD5-A nrPDB Length = 396 Score = 82.8 bits (203), Expect = 3e-16, Method: Composition-based stats. Identities = 37/143 (25%), Positives = 60/143 (41%), Gaps = 19/143 (13%) Query: 270 KRDGFV-------MGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGE 322 K+DG V + +GAA+LV+ E A + A ++ YG +G P G Sbjct: 241 KKDGTVTAGNASGINDGAAMLVVMAKEKAEELGIEPLATIVSYGTAG-----VDPKIMGY 295 Query: 323 GALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGA 382 G + AL+ A + E+I + A+ AA++ A+ + V+ A Sbjct: 296 GPVPATKKALEAANMTIEDIDLVEANEAF-----AAQSVAVIRDLNIDMNKVNVNGGAIA 350 Query: 383 TGHLLGAAGAVEAAFTTLACYYQ 405 GH +G +GA TTL + Sbjct: 351 IGHPIGCSGA--RILTTLLYEMK 371 Score = 43.9 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 23/122 (18%), Positives = 44/122 (36%), Gaps = 33/122 (27%) Query: 118 PTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVVSETALNFQTKGYNKVSP 177 + + AA+ A+K + P + + GV Sbjct: 31 AVELGVTAAKEAIKRANITPDMIDESLLGGVLTAG------------------------- 65 Query: 178 FFVPKILVNMAAGQVSIRYKL--KGPNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGG 235 L A Q+++ + + P ++ C +G +V + + IA GDAD+M+ GG Sbjct: 66 ------LGQNIARQIALGAGIPVEKPAMTINIVCGSGLRSVSMASQLIALGDADIMLVGG 119 Query: 236 TD 237 + Sbjct: 120 AE 121 >4WYS-A nrPDB Length = 405 Score = 80.9 bits (198), Expect = 1e-15, Method: Composition-based stats. Identities = 40/153 (26%), Positives = 58/153 (37%), Gaps = 19/153 (12%) Query: 270 KRDGFV-------MGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGE 322 + G V + +GAA LV+ E A+ A + Y G P G Sbjct: 240 DKAGTVTAGNASGINDGAAALVIMEESAALAAGLTPLARIKSYASGG-----VPPALMGM 294 Query: 323 GALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGA 382 G + AL+ AG+Q +I I A+ AA+ A+ + + V+ A Sbjct: 295 GPVPATQKALQLAGLQLADIDLIEANEAF-----AAQFLAVGKNLGFDSEKVNVNGGAIA 349 Query: 383 TGHLLGAAGAVEAAFTTLACYYQKLPPTLNLDC 415 GH +GA+GA TL Q TL L Sbjct: 350 LGHPIGASGA--RILVTLLHAMQARDKTLGLAT 380 >4N44-A nrPDB Length = 400 Score = 77.0 bits (188), Expect = 2e-14, Method: Composition-based stats. Identities = 40/144 (27%), Positives = 63/144 (43%), Gaps = 19/144 (13%) Query: 270 KRDGFV-------MGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGE 322 K+DG V + + AAVLV+ E A + + A+++ YG +G P G Sbjct: 236 KKDGTVTAGNASGLNDCAAVLVIMSAEKAKELGVKPLAKIVSYGSAG-----VDPAIMGY 290 Query: 323 GALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGA 382 G AA++ AG +E+ I ++ AA++ A+ K + V+ A Sbjct: 291 GPFYATKAAIEKAGWTVDELDLIESNEAF-----AAQSLAVAKDLKFDMNKVNVNGGAIA 345 Query: 383 TGHLLGAAGAVEAAFTTLACYYQK 406 GH +GA+GA TL QK Sbjct: 346 LGHPIGASGA--RILVTLVHAMQK 367 Score = 42.4 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 25/130 (19%), Positives = 48/130 (36%), Gaps = 33/130 (25%) Query: 108 SKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVVSETALNF 167 S D+ ++ + A + A+K +G P+ + ++V G + G+ + Sbjct: 20 SLKDVPAVD----LGATAIKEAVKKAGIKPE-DVNEVILGNVLQAGLGQNPARQASF--- 71 Query: 168 QTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSFRFIAHGD 227 P +P + +N C +G V + + I GD Sbjct: 72 -----KAGLPVEIPAMTINKV--------------------CGSGLRTVSLAAQIIKAGD 106 Query: 228 ADVMVAGGTD 237 ADV++AGG + Sbjct: 107 ADVIIAGGME 116 >4NZS-A nrPDB Length = 399 Score = 75.5 bits (184), Expect = 5e-14, Method: Composition-based stats. Identities = 34/142 (23%), Positives = 58/142 (40%), Gaps = 17/142 (11%) Query: 265 RPFHPKRDGFV-------MGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAP 317 RP K +G V + + AA +V+ E A +R + A ++ YG +G P Sbjct: 238 RPVFVKENGTVTAGNASGLNDAAAAVVMMERAEAERRGLKPLARLVSYGHAG-----VDP 292 Query: 318 DPEGEGALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVS 377 G G + AL+ AG+Q ++ I A+ AA+ A+ + + Sbjct: 293 KAMGIGPVPATKIALERAGLQVSDLDVIEANEAF-----AAQACAVTKALGLDPAKVNPN 347 Query: 378 STKGATGHLLGAAGAVEAAFTT 399 + + GH +GA GA+ Sbjct: 348 GSGISLGHPIGATGALITVKAL 369 Score = 42.7 bits (99), Expect = 4e-04, Method: Composition-based stats. Identities = 15/58 (25%), Positives = 26/58 (44%) Query: 181 PKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDS 238 P+ + V+ + P V+ C +G A+ + + I GD DV + GG +S Sbjct: 67 PRDMYLGRVAAVNGGVTINAPALTVNRLCGSGLQAIVSAAQTILLGDTDVAIGGGAES 124 >1NL7-A nrPDB Length = 392 Score = 73.6 bits (179), Expect = 2e-13, Method: Composition-based stats. Identities = 30/143 (20%), Positives = 54/143 (37%), Gaps = 19/143 (13%) Query: 270 KRDGFV-------MGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGE 322 ++G V + +GAA +L A +R + ++ + G P G Sbjct: 236 DKEGTVTAGNASGLNDGAAAALLMSEAEASRRGIQPLGRIVSWATVG-----VDPKVMGT 290 Query: 323 GALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGA 382 G + AL+ AG + ++ + A+ AA+ A+ + V+ A Sbjct: 291 GPIPASRKALERAGWKIGDLDLVEANEAF-----AAQACAVNKDLGWDPSIVNVNGGAIA 345 Query: 383 TGHLLGAAGAVEAAFTTLACYYQ 405 GH +GA+GA TL + Sbjct: 346 IGHPIGASGA--RILNTLLFEMK 366 Score = 33.5 bits (75), Expect = 0.20, Method: Composition-based stats. Identities = 14/30 (46%), Positives = 19/30 (63%) Query: 209 CTTGAHAVGDSFRFIAHGDADVMVAGGTDS 238 C +G AV + IA GDA ++VAGG +S Sbjct: 89 CGSGLRAVALGMQQIATGDASIIVAGGMES 118 >1WL4-A nrPDB Length = 397 Score = 71.3 bits (173), Expect = 8e-13, Method: Composition-based stats. Identities = 27/129 (20%), Positives = 46/129 (35%), Gaps = 10/129 (7%) Query: 276 MGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDA 335 + +GAA +VL + A +R A ++ + G P G G + + A+ A Sbjct: 254 INDGAAAVVLMKKSEADKRGLTPLARIVSWSQVG-----VEPSIMGIGPIPAIKQAVTKA 308 Query: 336 GVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEA 395 G E++ + AA + AI + + + A GH LGA+G Sbjct: 309 GWSLEDVDIFEINEAF-----AAVSAAIVKELGLNPEKVNIEGGAIALGHPLGASGCRIL 363 Query: 396 AFTTLACYY 404 Sbjct: 364 VTLLHTLER 372 Score = 32.3 bits (72), Expect = 0.47, Method: Composition-based stats. Identities = 25/120 (20%), Positives = 42/120 (35%), Gaps = 15/120 (12%) Query: 132 DSGWHPQSEADQVATGVAIGMGMIPL-------EVVSETALNFQTKGYNKVSPFFVPKIL 184 ++G P T + G + V + L T VS + + Sbjct: 2 NAGSDPVVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEV-IFGHV 60 Query: 185 VNMAAGQVSIRYKLKG-------PNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTD 237 + GQ +R G P + C +G AV + + I GD+ ++VAGG + Sbjct: 61 LAAGCGQNPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGME 120 >4C2K-A nrPDB Length = 417 Score = 70.9 bits (172), Expect = 1e-12, Method: Composition-based stats. Identities = 28/130 (21%), Positives = 54/130 (41%), Gaps = 17/130 (13%) Query: 270 KRDGFV-------MGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGE 322 K+DG V + +GA +++ + + A ++GY +SG P G Sbjct: 260 KKDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSG-----CDPSIMGI 314 Query: 323 GALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGA 382 G + ++ ALK AG+ +++ + + P + A++ V+ A Sbjct: 315 GPVPAISGALKKAGLSLKDMDLVEVNEAFAP-----QYLAVERSLDLDISKTNVNGGAIA 369 Query: 383 TGHLLGAAGA 392 GH LG +G+ Sbjct: 370 LGHPLGGSGS 379 Score = 37.7 bits (86), Expect = 0.012, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 36/77 (46%), Gaps = 12/77 (15%) Query: 174 KVSPFFVPKILVNMA----------AGQVSIRYKL--KGPNHAVSTACTTGAHAVGDSFR 221 KVSP V +++ A V +R + + P ++ C +G ++ + + Sbjct: 65 KVSPETVDSVIMGNVLQSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQ 124 Query: 222 FIAHGDADVMVAGGTDS 238 I +A+V++ GGT+S Sbjct: 125 EICVKEAEVVLCGGTES 141 >3SS6-A nrPDB Length = 394 Score = 69.7 bits (169), Expect = 3e-12, Method: Composition-based stats. Identities = 29/130 (22%), Positives = 53/130 (40%), Gaps = 17/130 (13%) Query: 270 KRDGFV-------MGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGE 322 ++DG V + +G+AVLVL E A ++ + A ++GY ++G P G Sbjct: 238 RKDGSVTAGNASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAG-----VDPKIMGI 292 Query: 323 GALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGA 382 G + L+ E+ + + AA+ A++ + V+ + Sbjct: 293 GPAPAIRKGLEKVDWSLEDADLLEINEAF-----AAQYLAVEKELDLDREKVNVNGSGVG 347 Query: 383 TGHLLGAAGA 392 GH +G GA Sbjct: 348 LGHPIGCTGA 357 Score = 37.7 bits (86), Expect = 0.011, Method: Composition-based stats. Identities = 10/36 (27%), Positives = 21/36 (58%) Query: 203 HAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDS 238 + + C++G A+ + I G ++V+VAGG ++ Sbjct: 85 YTIQRQCSSGMQAIMSAAMQIQLGVSEVVVAGGVEA 120 >6BN2-A nrPDB Length = 401 Score = 65.9 bits (159), Expect = 3e-11, Method: Composition-based stats. Identities = 24/131 (18%), Positives = 47/131 (35%), Gaps = 10/131 (7%) Query: 275 VMGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKD 334 + +GA+ LVL E + A+++ Y + AP+ + + AL Sbjct: 256 TLNDGASALVLMSKEKMESLGLKPLAKIVSYADAAQ-----APEWFTTAPAKALPIALAK 310 Query: 335 AGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVE 394 A + +I + + + +G A + A + V+ A GH LG++G+ Sbjct: 311 ANLTINDIDFFEFNEAFSVVG-----LANNKILGLDAAKVNVNGGAVALGHPLGSSGSRI 365 Query: 395 AAFTTLACYYQ 405 Sbjct: 366 IVTLINVLKQN 376 Score = 36.6 bits (83), Expect = 0.026, Method: Composition-based stats. Identities = 14/46 (30%), Positives = 22/46 (47%), Gaps = 4/46 (8%) Query: 196 YKLKGPNHAVSTA----CTTGAHAVGDSFRFIAHGDADVMVAGGTD 237 PN +TA C +G AV + + + GD + +VAGG + Sbjct: 79 LGAGLPNTTPTTAVNKVCASGMKAVMMAAQAVKAGDVEAIVAGGME 124 >1ULQ-A nrPDB Length = 401 Score = 65.1 bits (157), Expect = 6e-11, Method: Composition-based stats. Identities = 32/132 (24%), Positives = 51/132 (38%), Gaps = 14/132 (10%) Query: 276 MGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDA 335 + +GAA ++L ++A R A V ++G P G G + AL+ A Sbjct: 255 LNDGAAAVLLVSDDYAKAHGLRPLARVRAIAVAG-----VPPRIMGIGPVPATRKALERA 309 Query: 336 GVQPEEISYINAHATSTPLGDAAENKAIKHL--FKDHAYALAVSSTKGATGHLLGAAGAV 393 G+ ++ I + AA+ A+ L + A GH LGA+GA Sbjct: 310 GLSFSDLGLIELNEAF-----AAQALAVLREWSLSMEDQRLNPNGGAIALGHPLGASGA- 363 Query: 394 EAAFTTLACYYQ 405 TTL + Sbjct: 364 -RILTTLVHEMR 374 Score = 28.5 bits (62), Expect = 5.7, Method: Composition-based stats. Identities = 11/35 (31%), Positives = 17/35 (48%) Query: 204 AVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDS 238 V+ C +G AV + R I G+ V + G +S Sbjct: 84 TVNRLCGSGLEAVAQAARAIWAGEGKVYIGSGVES 118 >5LP7-H nrPDB Length = 393 Score = 63.5 bits (153), Expect = 2e-10, Method: Composition-based stats. Identities = 28/128 (21%), Positives = 46/128 (35%), Gaps = 12/128 (9%) Query: 276 MGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDA 335 + +GA VL E A + R A +LG+ +G H A P + LK Sbjct: 250 VNDGAGAFVLMSEEKAAELGKRPLATILGFSTTGMPAHELAAAPG-----FAINKLLKKN 304 Query: 336 GVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEA 395 G+ ++I + + + + + V+ A GH +GA+GA Sbjct: 305 GLTVQDIDLFEVNEAFASV-----VLTCEKIVGFDLEKVNVNGGAIALGHPIGASGA--R 357 Query: 396 AFTTLACY 403 TL Sbjct: 358 ILMTLVYE 365 Score = 38.1 bits (87), Expect = 0.008, Method: Composition-based stats. Identities = 19/66 (28%), Positives = 32/66 (48%), Gaps = 7/66 (10%) Query: 180 VPKILVNMAAGQVSIRYKLK-------GPNHAVSTACTTGAHAVGDSFRFIAHGDADVMV 232 V ++V +GQ+ R + P+ ++ C +G AV + I DAD++V Sbjct: 52 VMGMVVQAGSGQIPSRQAARLAGMPWSVPSETLNKVCASGLRAVTLCDQMIRAQDADILV 111 Query: 233 AGGTDS 238 AGG +S Sbjct: 112 AGGMES 117 >1WDK-C nrPDB Length = 390 Score = 58.9 bits (141), Expect = 5e-09, Method: Composition-based stats. Identities = 22/117 (18%), Positives = 41/117 (35%), Gaps = 7/117 (5%) Query: 276 MGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDA 335 + +GA+ +++ + A A + ++G P G G + ALK A Sbjct: 244 ITDGASCMIVMSAQRAKDLGLEPLAVIRSMAVAG-----VDPAIMGYGPVPATQKALKRA 298 Query: 336 GVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGA 392 G+ +I +I + A + + + A GH G +GA Sbjct: 299 GLNMADIDFIELNEAF--AAQALPVLKDLKVLDKMNEKVNLHGGAIALGHPFGCSGA 353 Score = 33.5 bits (75), Expect = 0.18, Method: Composition-based stats. Identities = 14/54 (25%), Positives = 23/54 (42%), Gaps = 2/54 (3%) Query: 184 LVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTD 237 + MA+ I + VS C + A+ + + I G+ DV V GG + Sbjct: 71 IARMASLMTQIPH--TSAAQTVSRLCGSSMSALHTAAQAIMTGNGDVFVVGGVE 122 >5CBQ-A nrPDB Length = 413 Score = 58.5 bits (140), Expect = 6e-09, Method: Composition-based stats. Identities = 26/119 (21%), Positives = 48/119 (40%), Gaps = 13/119 (10%) Query: 277 GEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAG 336 + A++ ++ E A + + ++ +G +G APD G G + AL AG Sbjct: 265 NDAASMCIVTTPEKAAELGLKPLVRLVSWGSAG-----VAPDLMGIGPVPATEVALAKAG 319 Query: 337 VQPEEISYINAHATSTPLGDAAENKAIKHL--FKDHAY-ALAVSSTKGATGHLLGAAGA 392 + +I I + AA+ A+ F + + V + + GH +GA G Sbjct: 320 LTLADIDLIELNEAF-----AAQALAVMREWKFGEADHERTNVRGSGISLGHPVGATGG 373 Score = 36.6 bits (83), Expect = 0.022, Method: Composition-based stats. Identities = 14/38 (36%), Positives = 20/38 (52%) Query: 201 PNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDS 238 P V C +G AV + + GD D++VAGG +S Sbjct: 88 PGMQVDRRCGSGLQAVIQACLQVRSGDHDLVVAGGAES 125 >2WUA-A nrPDB Length = 440 Score = 57.0 bits (136), Expect = 2e-08, Method: Composition-based stats. Identities = 27/117 (23%), Positives = 47/117 (40%), Gaps = 10/117 (8%) Query: 276 MGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDA 335 + +GA ++L + A+Q+ I + G P G G + AA+K A Sbjct: 277 VSDGAGAVLLMKRSIALQKGLPILGVFRTFAAVG-----VPPSIMGIGPAVAIPAAVKAA 331 Query: 336 GVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGA 392 G+Q ++I + A++ + + + V+ A GH LGA GA Sbjct: 332 GLQIDDIDLFEINEAF-----ASQFVYCQKKLEIDPQKINVNGGAMAIGHPLGATGA 383 >2C7Y-A nrPDB Length = 404 Score = 56.6 bits (135), Expect = 2e-08, Method: Composition-based stats. Identities = 28/130 (21%), Positives = 51/130 (39%), Gaps = 17/130 (13%) Query: 270 KRDGFV-------MGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGE 322 K+DG + +GA ++L + A+Q+ + + G P G Sbjct: 244 KKDGTTTAGNSSQVSDGAGAVLLMKRSVAMQKGLPVLGVFRTFAAVG-----VDPAIMGI 298 Query: 323 GALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGA 382 G + AA+K AG++ ++I + A++ ++ + V+ A Sbjct: 299 GPAVAIPAAVKAAGLELDDIDLFEINEAF-----ASQFVYCRNKLGLDPEKINVNGGAMA 353 Query: 383 TGHLLGAAGA 392 GH LGA GA Sbjct: 354 IGHPLGATGA 363 >4O9A-A nrPDB Length = 398 Score = 56.2 bits (134), Expect = 3e-08, Method: Composition-based stats. Identities = 29/143 (20%), Positives = 50/143 (34%), Gaps = 19/143 (13%) Query: 270 KRDGFV-------MGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGE 322 + G V + +GAA +V+ A + A + Y +G P G Sbjct: 242 DKAGTVTAANASGLNDGAAAVVVMSAAKAKELGLTPLATIKSYANAG-----VDPKVMGM 296 Query: 323 GALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGA 382 G + AL A P+++ + + AA+ A+ + V+ A Sbjct: 297 GPVPASKRALSRAEWTPQDLDLMEINEAF-----AAQALAVHQQMGWDTSKVNVNGGAIA 351 Query: 383 TGHLLGAAGAVEAAFTTLACYYQ 405 GH +GA+G TL + Sbjct: 352 IGHPIGASGC--RILVTLLHEMK 372 Score = 34.3 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 23/110 (20%), Positives = 40/110 (36%), Gaps = 31/110 (28%) Query: 129 AMKDSGWHPQSEADQVATGVAI-GMGMIPLEVVSETALNFQTKGYNKVSPFFVPKILVNM 187 A++ +G P+ ++ + V G G P + P VP + +N Sbjct: 42 ALERAGVKPEQVSEVIMGQVLTAGSGQNPA----------RQAAIKAGLPAMVPAMTINK 91 Query: 188 AAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTD 237 +G +G AV + I GDA+++VAGG + Sbjct: 92 VSG--------------------SGLKAVMLAANAIMAGDAEIVVAGGQE 121 >3GOA-A nrPDB Length = 387 Score = 56.2 bits (134), Expect = 3e-08, Method: Composition-based stats. Identities = 27/129 (20%), Positives = 45/129 (34%), Gaps = 15/129 (11%) Query: 276 MGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDA 335 + +GAA +++ A + + A + + G P G G + ALK A Sbjct: 241 LSDGAAAMLVMSESRARELGLKPRARIRSMAVVG-----CDPSIMGYGPVPASKLALKKA 295 Query: 336 GVQPEEISYINAHATSTPLGDAAENKAIKHLFK---DHAYALAVSSTKGATGHLLGAAGA 392 G+ +I + AA+ + ++ A GH LG +GA Sbjct: 296 GLSASDIDVFEMNEAF-----AAQILPCIKDLGLMEQIDEKINLNGGAIALGHPLGCSGA 350 Query: 393 VEAAFTTLA 401 TTL Sbjct: 351 --RISTTLI 357 Score = 40.0 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 13/37 (35%), Positives = 19/37 (51%) Query: 201 PNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTD 237 P V+ C + A+ D+ R I GDA V + GG + Sbjct: 83 PAVTVNRLCGSSMQALHDAARMIMTGDAQVCLVGGVE 119 >3SVK-A nrPDB Length = 407 Score = 53.1 bits (126), Expect = 3e-07, Method: Composition-based stats. Identities = 22/118 (18%), Positives = 41/118 (34%), Gaps = 10/118 (8%) Query: 276 MGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDA 335 + +GAA++++ + + A ++ SG + P G L A Sbjct: 264 IVDGAALVLVGSEKAGKSQGLTPRARIVATATSG-----SDPVIMLTGPTPATRKVLDRA 318 Query: 336 GVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAV 393 G+ ++I + + + L V+ A GH LGA GA+ Sbjct: 319 GLTIDDIDLFELNEAFASV-----VLKFQKDLNIPDEKLNVNGGAIAMGHPLGATGAM 371 Score = 38.1 bits (87), Expect = 0.008, Method: Composition-based stats. Identities = 23/92 (25%), Positives = 40/92 (43%), Gaps = 12/92 (13%) Query: 209 CTTGAHAVGDSFRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALSTNSDPKLACRPFH 268 C +G AV + + + G D+++AGG +S +S + + A A +DP+ R Sbjct: 96 CASGLEAVNTAAQKVRSGWDDLVLAGGVES-MSRVPMGSDGGAWA----TDPETNYRI-- 148 Query: 269 PKRDGFVMGEGAAVLVLEEYEHAVQRRARIYA 300 GFV +G ++ E + YA Sbjct: 149 ----GFVP-QGIGADLIATLEGFSREDVDAYA 175 >5XYJ-B nrPDB Length = 408 Score = 53.1 bits (126), Expect = 3e-07, Method: Composition-based stats. Identities = 39/186 (20%), Positives = 70/186 (37%), Gaps = 28/186 (15%) Query: 234 GGTDSCISPLSLAGFSRA--RALSTNSDPKL-------ACRPFHPKRDGFV-------MG 277 G D+ I P+++ GF ++ + +P + R K +G V + Sbjct: 206 GKFDNEIVPVTIKGFRGKPDTQVTKDEEPARLHVEKLRSARTVFQKENGTVTAANASPIN 265 Query: 278 EGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGV 337 +GAA ++L + ++ + A + G+G +A H P + ALK AG+ Sbjct: 266 DGAAAVILVSEKVLKEKNLKPLAIIKGWG---EAAH--QPADFTWAPSLAVPKALKHAGI 320 Query: 338 -QPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAA 396 + Y + + +G + K + V A GH LG +GA Sbjct: 321 EDINSVDYFEFNEAFSVVGLVN-----TKILKLDPSKVNVYGGAVALGHPLGCSGA-RVV 374 Query: 397 FTTLAC 402 T L+ Sbjct: 375 VTLLSI 380 Score = 35.4 bits (80), Expect = 0.055, Method: Composition-based stats. Identities = 18/65 (27%), Positives = 29/65 (44%), Gaps = 2/65 (3%) Query: 191 QVSIRYKLKG--PNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDSCISPLSLAGF 248 QV++ L V+ + A+ + I G+ADV+VAGG +S + Sbjct: 81 QVALAAGLSNHIVASTVNKVAASAMKAIILGAQSIKCGNADVVVAGGCESMTNAPYYMPA 140 Query: 249 SRARA 253 +RA A Sbjct: 141 ARAGA 145 >2IIK-A nrPDB Length = 418 Score = 52.4 bits (124), Expect = 4e-07, Method: Composition-based stats. Identities = 24/130 (18%), Positives = 43/130 (33%), Gaps = 10/130 (7%) Query: 276 MGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDA 335 + +GAA ++L A + I + Y + G PD G G + AL+ A Sbjct: 272 VSDGAAAILLARRSKAEELGLPILGVLRSYAVVG-----VPPDIMGIGPAYAIPVALQKA 326 Query: 336 GVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEA 395 G+ ++ + A++ + + A GH LG GA + Sbjct: 327 GLTVSDVDIFEINEAF-----ASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGARQV 381 Query: 396 AFTTLACYYQ 405 + Sbjct: 382 ITLLNELKRR 391 Score = 28.9 bits (63), Expect = 5.0, Method: Composition-based stats. Identities = 12/38 (31%), Positives = 19/38 (50%) Query: 201 PNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDS 238 P V+ C++G AV I +G D+ +A G +S Sbjct: 109 PLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVES 146 >2IBU-A nrPDB Length = 395 Score = 52.0 bits (123), Expect = 5e-07, Method: Composition-based stats. Identities = 23/131 (17%), Positives = 48/131 (36%), Gaps = 10/131 (7%) Query: 275 VMGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKD 334 + +GAA LVL + A + A ++ + + P + + LKD Sbjct: 253 TLNDGAAALVLMTADAAKRLNVTPLARIVAFADAA-----VEPIDFPIAPVYAASMVLKD 307 Query: 335 AGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVE 394 G++ E+I+ + + + A + + + ++ + GH +G +GA Sbjct: 308 VGLKKEDIAMWEVNEAFSLV-----VLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARI 362 Query: 395 AAFTTLACYYQ 405 T A Sbjct: 363 VGHLTHALKQG 373 Score = 40.0 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 13/38 (34%), Positives = 21/38 (55%) Query: 201 PNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDS 238 P ++ C +G A+ + + + G DVMVAGG +S Sbjct: 86 PCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMES 123 >6BJB-A nrPDB Length = 393 Score = 52.0 bits (123), Expect = 6e-07, Method: Composition-based stats. Identities = 24/118 (20%), Positives = 45/118 (38%), Gaps = 10/118 (8%) Query: 275 VMGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKD 334 + +GAA++V+ + A + + A +L YG + T P G + LK Sbjct: 251 TLNDGAAMVVMTTVDGAKKHGLKPLARMLAYGDAA-----THPIDFGIAPASVIPKVLKL 305 Query: 335 AGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGA 392 AG+Q ++I + +K + + + GH +G +GA Sbjct: 306 AGLQIKDIDLWEINEAFA----VVPLYTMKT-LGLDESKVNIHGGAVSLGHPIGMSGA 358 >6ARG-A nrPDB Length = 399 Score = 51.6 bits (122), Expect = 6e-07, Method: Composition-based stats. Identities = 34/152 (22%), Positives = 54/152 (35%), Gaps = 19/152 (12%) Query: 257 NSDPKLACRPFHPKRDGFV-------MGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSG 309 N + A +P G V + +GAA +VL + + A++LG+G + Sbjct: 230 NPEKLRAIKPAFIPGSGTVTAPNSSPLNDGAAAVVLVSEAKLKELNLKPVAKILGWGDAA 289 Query: 310 DAGHITAPDPEGEGALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKD 369 P + ALK AGV + I + + + A L Sbjct: 290 Q-----QPSKFTTAPALAIPKALKHAGVGQDAIDAFEINEAFSVV-----ALANMKLLGI 339 Query: 370 HAYALAVSSTKGATGHLLGAAGAVEAAFTTLA 401 + + A GH +GA+GA TTL Sbjct: 340 PEEKVNLHGGAVAIGHPIGASGA--RILTTLL 369 Score = 40.8 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 15/37 (40%), Positives = 22/37 (59%) Query: 202 NHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDS 238 V+ C +G A+ + I G+ADV+VAGGT+S Sbjct: 86 CTTVNKVCASGLKAIILGAQTIMTGNADVVVAGGTES 122 >2EBD-A nrPDB Length = 309 Score = 50.5 bits (119), Expect = 2e-06, Method: Composition-based stats. Identities = 53/283 (18%), Positives = 95/283 (33%), Gaps = 73/283 (25%) Query: 119 TIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVVSETALNFQTKGYNKVSPF 178 T MA AA+ A++++ P+ L+++ L Q + + Sbjct: 51 TYMATQAAKEALREANLSPEE-----------------LDLIILATLTPQKRFPST---- 89 Query: 179 FVPKILVNMAAGQVSIRYKLKGP-NHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTD 237 A V + K KG +S AC+ +A+ + FI G A ++ G + Sbjct: 90 ----------ACLVQAQLKAKGVYAFDISAACSGFIYALDIADSFIKSGKAKNVLVIGAE 139 Query: 238 SCISPLSLAGFSRARALSTNSDPKLACRPFHPKRDGFVM-GEGAAVLVLEEYEH-AVQRR 295 + R V+ G+GA +V+ E + Sbjct: 140 KLSEAVDWE-----------------------DRSTCVLFGDGAGAVVVTRSEDKSDILA 176 Query: 296 ARIYA----EVLGYGLSGDAGHITAPDPEGEGALRCM----AAALKDAGVQPEEISYINA 347 R+YA E L + + + A+R M L+ AGV+PEE+S + Sbjct: 177 TRMYAEGSLEELLHADNC-GYIRMKGRELFKVAVRSMEEVCREVLEKAGVKPEEVSLVIP 235 Query: 348 HATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAA 390 H + + A+ + V+ K G+ A+ Sbjct: 236 HQANVRI-----INALAEKLNIPKEKVFVNIQKY--GNTSAAS 271 >4B3J-C nrPDB Length = 403 Score = 49.3 bits (116), Expect = 3e-06, Method: Composition-based stats. Identities = 22/118 (18%), Positives = 39/118 (33%), Gaps = 10/118 (8%) Query: 276 MGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDA 335 + +GAA++++ + A ++ SG P G L A Sbjct: 260 IVDGAALVMIGSAAAGKLQGLTPRARIVATATSG-----ADPVIMLTGPTPATRKVLDRA 314 Query: 336 GVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAV 393 G+ ++I + + + L V+ A GH LGA GA+ Sbjct: 315 GLTVDDIDLFELNEAFASV-----VLKFQKDLNIPDEKLNVNGGAIAMGHPLGATGAM 367 Score = 34.3 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 10/30 (33%), Positives = 18/30 (60%) Query: 209 CTTGAHAVGDSFRFIAHGDADVMVAGGTDS 238 C +G AV + + + G D+++AGG +S Sbjct: 92 CASGLEAVNTAAQKVRSGWDDLVLAGGVES 121 >6BJA-A nrPDB Length = 397 Score = 49.3 bits (116), Expect = 4e-06, Method: Composition-based stats. Identities = 29/129 (22%), Positives = 44/129 (34%), Gaps = 10/129 (7%) Query: 275 VMGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKD 334 + +GAA VL E + R + A+VL Y +G P + L Sbjct: 255 TINDGAAACVLASGEVVQEGRLKPIAKVLSYAEAG-----VEPIDFTVAPALAVKQLLSQ 309 Query: 335 AGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVE 394 +G+ E I+ + + G A + + V A GH LGA+GA Sbjct: 310 SGLDEESIALWEINEAFSVTG-----LAFIKELRLDPKRVNVRGGAVALGHPLGASGARI 364 Query: 395 AAFTTLACY 403 A Sbjct: 365 VVTLVHALK 373 Score = 31.6 bits (70), Expect = 0.69, Method: Composition-based stats. Identities = 8/37 (21%), Positives = 18/37 (48%) Query: 202 NHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDS 238 ++ C++ A+ + I G ++VA G++S Sbjct: 88 CVTINKVCSSSMKAIIMGAQAIQVGYRRIVVALGSES 124 >4UBW-A nrPDB Length = 399 Score = 45.8 bits (107), Expect = 4e-05, Method: Composition-based stats. Identities = 20/117 (17%), Positives = 44/117 (37%), Gaps = 10/117 (8%) Query: 276 MGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDA 335 + +GAA ++ + A A ++ L G P +G ++ A L+ A Sbjct: 256 ISDGAAAVLWMDEAVARAHGLTPRARIVAQALVG-----AEPYYHLDGPVQSTAKVLEKA 310 Query: 336 GVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGA 392 G++ +I + + + + + + + V+ A GH +G G+ Sbjct: 311 GMKIGDIDIVEINEAFASV-----VLSWARVHEPDMDRVNVNGGAIALGHPVGCTGS 362 >1PXT-A nrPDB Length = 390 Score = 43.1 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 29/150 (19%), Positives = 47/150 (31%), Gaps = 17/150 (11%) Query: 265 RP-FHPKRDGFVMG------EGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAP 317 RP F R G +G A ++L A Q + + + G P Sbjct: 231 RPAFIKDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVG-----VPP 285 Query: 318 DPEGEGALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVS 377 + G G + L+ G+Q ++I + AA+ H + Sbjct: 286 EIMGVGPAYAIPKVLEATGLQVQDIDIFEINEAF-----AAQALYCIHKLGIDLNKVNPR 340 Query: 378 STKGATGHLLGAAGAVEAAFTTLACYYQKL 407 A GH LG GA + A ++ Sbjct: 341 GGAIALGHPLGCTGARQVATILRELKKDQI 370 Score = 32.0 bits (71), Expect = 0.51, Method: Composition-based stats. Identities = 14/50 (28%), Positives = 23/50 (46%) Query: 189 AGQVSIRYKLKGPNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDS 238 A ++ P A++ C++G AV D I G D+ +A G +S Sbjct: 78 AACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVES 127 >5ZQZ-B nrPDB Length = 474 Score = 41.6 bits (96), Expect = 7e-04, Method: Composition-based stats. Identities = 20/82 (24%), Positives = 33/82 (40%), Gaps = 7/82 (8%) Query: 163 TALNFQTKGYNKVSPFFVPKILVNMAA-------GQVSIRYKLKGPNHAVSTACTTGAHA 215 T L +T +V + + ++ + + K P H V+ AC + A Sbjct: 85 TGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQA 144 Query: 216 VGDSFRFIAHGDADVMVAGGTD 237 + IA G DV+VAGG + Sbjct: 145 MTTGVGLIASGQCDVIVAGGVE 166 Score = 35.8 bits (81), Expect = 0.041, Method: Composition-based stats. Identities = 21/131 (16%), Positives = 41/131 (31%), Gaps = 22/131 (16%) Query: 276 MGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGE---GALRCMAAAL 332 + +GA+ +++ E A+ + A + + + DP+ + G L Sbjct: 311 LTDGASAMLIMAEEKALAMGYKPKAYLRDF-------MYVSQDPKDQLLLGPTYATPKVL 363 Query: 333 KDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDH--AYALAVS----------STK 380 + AG+ +I H + A F ++ V Sbjct: 364 EKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRKTKVGLPPLEKFNNWGGS 423 Query: 381 GATGHLLGAAG 391 + GH GA G Sbjct: 424 LSLGHPFGATG 434 >4YZO-A nrPDB Length = 373 Score = 41.2 bits (95), Expect = 9e-04, Method: Composition-based stats. Identities = 34/199 (17%), Positives = 66/199 (33%), Gaps = 43/199 (21%) Query: 276 MGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGA--LRCMAAALK 333 + +GAA +V+ E A+ ++ + G G S +++ + + A K Sbjct: 199 ISDGAAAVVMVRNEDALSYTSKPV-YIKGIGSSNYTAYVSEKEDFVTLPAVVEASRKAFK 257 Query: 334 DAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGA----------- 382 A V E I + H +T + + +++ I K + + Sbjct: 258 KAKV--ERIDFAELHDMAT-ILEIIQSEDIGLFKKGEGWKAVMEGLTSLDGEIPINPSGG 314 Query: 383 ---TGHLLGAAGAVEAAFTTLACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFI 439 GH +GA+G +A +A + + + Sbjct: 315 LNSKGHPIGASGVAQAVEAFSQIR-----------------------NEAGNRQVKNARV 351 Query: 440 GLTNSFGFGGTNATLCIAG 458 GL+ S G +AT+ I G Sbjct: 352 GLSLSMAGYGNSATVIIYG 370 >4X0O-A nrPDB Length = 362 Score = 40.4 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 33/193 (17%), Positives = 56/193 (29%), Gaps = 50/193 (25%) Query: 181 PKILVNMAAGQVSIRYKL-KGPNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDSC 239 P L+ A +V + ++ ACT + + + R + + G + Sbjct: 84 PDSLIPNIASRVQQNLGIPSAAAFDLNAACTGFLYGLETATRLMQASHYRHALVIGAE-- 141 Query: 240 ISPLSLAGFSRARALSTNSDPKLACRPFHPKRDGFVMGEGAAVLVLEEYEH--------- 290 LS D + + + G+GA +VL + E Sbjct: 142 -------------RLSFYLD-------WTKRDTAVLFGDGAGAVVLSKTEQKVGLQDAQI 181 Query: 291 -AVQRRARIYAEVLGYGLSGDAGH--------------ITAPDPEGEGALRCMAAALKDA 335 + I A V +G + D I G GA L + Sbjct: 182 GCDAQGRDILA-VPKFGTAMDRFDADNGYWAFDFVGKEIFKRAVRGMGA--AAQQVLARS 238 Query: 336 GVQPEEISYINAH 348 G+ EEI + H Sbjct: 239 GLSTEEIDVVIPH 251 >4BI9-A nrPDB Length = 454 Score = 40.4 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 29/151 (19%), Positives = 49/151 (32%), Gaps = 18/151 (11%) Query: 264 CRPFHPKRDGFVMGEGAAVLVLEEYEHAVQRRARI----YAEVLGYGLSGDAGHITAPD- 318 +PF D + +G A ++L E + E+ + + +PD Sbjct: 262 YKPFLRTTDCSQVSDGGAAVILASEEGLQKLGLSPNDNRLVEIKSLASAAGNLYEDSPDL 321 Query: 319 PEGEGALRCMAAALKDAGVQPEEISYINAHATSTPLGDAA-ENKAIKHLFKDHAY----- 372 ++ AL AGV+PE++ H T E I A Sbjct: 322 TRMTTSMVAARTALSMAGVKPEQLQVAEVHDCFTIAELLMYEALGIAEYGGAGALIRSGA 381 Query: 373 -----ALAVSSTKGAT--GHLLGAAGAVEAA 396 + V++ G GH +GA G + Sbjct: 382 TALDGRIPVNTGGGLLSFGHPVGATGVKQVL 412 Score = 32.3 bits (72), Expect = 0.47, Method: Composition-based stats. Identities = 13/64 (20%), Positives = 26/64 (40%), Gaps = 6/64 (9%) Query: 174 KVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSFRFIAHGDADVMVA 233 + P V + + ++ L P V AC +G AV ++ + G + + +A Sbjct: 107 HLGPAAVGSLSGSNSSAF------LNKPAVRVEGACASGGLAVQSAWEALLAGTSQIALA 160 Query: 234 GGTD 237 G + Sbjct: 161 VGVE 164 Score = 32.3 bits (72), Expect = 0.49, Method: Composition-based stats. Identities = 13/86 (15%), Positives = 26/86 (30%), Gaps = 10/86 (11%) Query: 50 GLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDEGQFNEQNFVSK 109 G G+ W+ L+ G S I + V + G Sbjct: 134 GACASGGLAVQSAWEALLAGTSQIA---------LAVGVEVQTTVSARVGGDYLARAAHY 184 Query: 110 SDIKSMSSPTIMAIGAAEL-AMKDSG 134 + + T + A + A++++G Sbjct: 185 KRQRQLDDFTFPCLFARRMKAIQEAG 210 >2AJ9-A nrPDB Length = 356 Score = 40.0 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 33/189 (17%), Positives = 59/189 (31%), Gaps = 42/189 (22%) Query: 188 AAGQVSIRYKLKGP-NHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDSCISPLSLA 246 AA V+ KG +S C +A+G + I G A M+ GT+ + + Sbjct: 121 AAPMVAASLGAKGILGFDLSAGCAGFGYALGAAADMIRGGGAATMLVVGTEKLSPTIDM- 179 Query: 247 GFSRARALSTNSDPKLACRPFHPKRDGFVMGEGAAVLVLEEYEH-------AVQRRARIY 299 + F+ +GAA +V+ E A + Sbjct: 180 --------------------YDAGNC-FIFADGAAAVVVGETPFQGIGPTVAGSDGEQAD 218 Query: 300 AEVLGYGLSGDAGHITAPDPEGEGALRCM------------AAALKDAGVQPEEISYINA 347 A A + + P P + A+ AGV+P++I Sbjct: 219 AIRQDIDWITFAQNPSGPRPFVRLEGPAVFRWAAFKMGDVGRRAMDAAGVRPDQIDVFVP 278 Query: 348 HATSTPLGD 356 H ++ + + Sbjct: 279 HQANSRINE 287 Score = 29.3 bits (64), Expect = 4.2, Method: Composition-based stats. Identities = 23/99 (23%), Positives = 37/99 (37%), Gaps = 10/99 (10%) Query: 322 EGALRCMAAALKDAGVQPEEISYI----NAHATSTPLGDAAENKAIKHLFKDHAYALAVS 377 A AL +AG+ +I + N H TP ++ +S Sbjct: 84 SMATEACRRALSNAGLSAADIDGVIVTTNTHFLQTPPAAPMVAASLG---AKGILGFDLS 140 Query: 378 STKGATGHLLGAAGAV---EAAFTTLACYYQKLPPTLNL 413 + G+ LGAA + A T L +KL PT+++ Sbjct: 141 AGCAGFGYALGAAADMIRGGGAATMLVVGTEKLSPTIDM 179 >4NHD-A nrPDB Length = 319 Score = 39.3 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 30/136 (22%), Positives = 50/136 (36%), Gaps = 29/136 (21%) Query: 188 AAGQVSIRYKLKG-PNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDSCISPLSLA 246 AA QV + +KG P ++ AC+ +A+ + + + G ++ G D Sbjct: 93 AACQVQGKLGIKGCPAFDLAAACSGFMYALSIADQHVKSGMCKHVLVIGAD--------- 143 Query: 247 GFSRARALSTNSDPKLACRPFHPKRDGFVM-GEGAAVLVLEEYEHAVQRRARIYAEVLGY 305 ALS DP R ++ G+GA +V+ I+A+ Sbjct: 144 ------ALSKTCDPT--------DRSTIILFGDGAGAVVVGASNEPGILSTHIHAD---- 185 Query: 306 GLSGDAGHITAPDPEG 321 G GD + P G Sbjct: 186 GEFGDLLSLEVPVRGG 201 >4EWP-A nrPDB Length = 350 Score = 38.9 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 46/266 (17%), Positives = 79/266 (29%), Gaps = 60/266 (22%) Query: 127 ELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVVSETALNFQTKGYNKVSPFFVPKILVN 186 E + +G + A T + +G E + L VS P + Sbjct: 42 EWIRQRTGIVTRQRATAEETVPVMAVG-AAREALERAGLQGSDLDAVIVSTVTFPHATPS 100 Query: 187 MAAGQVSIRYKLK-GPNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDSCISPLSL 245 AA V+ P + VS AC + V + + G A ++ G + Sbjct: 101 -AAALVAHEIGATPAPAYDVSAACAGYCYGVAQADALVRSGTARHVLVVGVE-------- 151 Query: 246 AGFSRARALSTNSDPKLACRPFHPKRDGFVMGEGAAVLVL-------------------- 285 LS DP F ++G+GA +++ Sbjct: 152 -------RLSDVVDPTDRSISF-------LLGDGAGAVIVAASDEPGISPSVWGSDGERW 197 Query: 286 ----EEYEHAVQRRARIYAEVLGYGLS-GDAGHITAPDPEGEGA----------LRCMAA 330 + R A +A G + A + P +G + Sbjct: 198 STISMTHSQLELRDAVEHARTTGDASAITGAEGMLWPTLRQDGPSVFRWAVWSMAKVARE 257 Query: 331 ALKDAGVQPEEISYINAHATSTPLGD 356 AL AGV+PE+++ H + + D Sbjct: 258 ALDAAGVEPEDLAAFIPHQANMRIID 283 >6ESQ-A nrPDB Length = 392 Score = 38.1 bits (87), Expect = 0.008, Method: Composition-based stats. Identities = 16/59 (27%), Positives = 27/59 (45%), Gaps = 5/59 (8%) Query: 201 PNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALSTNSD 259 P V AC +G+ A+ + +A G DV++AGG + A+++ SD Sbjct: 77 PCTRVEAACASGSLALRSAVLSVASGHHDVVLAGGVEKMTDVE-----DATAAIASASD 130 Score = 31.2 bits (69), Expect = 0.92, Method: Composition-based stats. Identities = 29/140 (20%), Positives = 48/140 (34%), Gaps = 22/140 (15%) Query: 276 MGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEG-----ALRCMAA 330 + +GA+ L++ + + A + + E++ S A A + A Sbjct: 209 VSDGASALIVCDADKAEEFAPK--DEIIYIKASTQASDTIALHDREDMTTLNAAKVASEK 266 Query: 331 ALKDAGVQPEEISYINAHATST-------------PLGDAAENKAIKHLFKDHAYALAV- 376 A K A + PE+I H GDA + + D+ + V Sbjct: 267 AYKLAKIAPEKIDVAEVHDCFAINGLILVEDLGFCKKGDAGKVIDEGKIRIDYDDFVTVN 326 Query: 377 -SSTKGATGHLLGAAGAVEA 395 S A GH LGA G + Sbjct: 327 PSGGLKAAGHALGATGIRQV 346 >4U4E-A nrPDB Length = 383 Score = 38.1 bits (87), Expect = 0.009, Method: Composition-based stats. Identities = 48/190 (25%), Positives = 70/190 (36%), Gaps = 20/190 (10%) Query: 169 TKGYNKVS-PFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSFRFIAHGD 227 G ++V P VP + GQ Y L P A + AC+ G + + Sbjct: 108 ESGRSRVGMPPRVPA--PDSLRGQFEDPYGLPTPVGAYALACSRHMAEYGTTKEQL---- 161 Query: 228 ADVMVAGGTDSCISPLSLAGFSRARALSTNSDPKLACRP----FHPKRDGFVMGEGAAVL 283 A++ VA + ++P + R T D L RP F+ V + Sbjct: 162 AEIAVATRKWAMLNPKAY-----MRDPITIED-VLNSRPIVWPFNLLDCCLVT-DAGGAC 214 Query: 284 VLEEYEHAVQRRARIYAEVLGYGLSGDAGHITA-PDPEGEGALRCMAAALKDAGVQPEEI 342 V+ E A R A +LG G S D I+ P A R AA K AGV ++I Sbjct: 215 VVTSIERARDLRQHPVA-ILGVGESHDHSIISQMPSLTSFAARRSGQAAFKMAGVTHDDI 273 Query: 343 SYINAHATST 352 + + T Sbjct: 274 DLAMIYDSFT 283 >4ANI-C nrPDB Length = 509 Score = 36.6 bits (83), Expect = 0.023, Method: Composition-based stats. Identities = 17/88 (19%), Positives = 29/88 (32%), Gaps = 4/88 (4%) Query: 328 MAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLL 387 + AL+DAG+ P +I + ST + E AIK + A G + Sbjct: 289 VRQALQDAGLTPADIDKVILVGGSTRIPAVQE--AIKRELGKEPHKGVNPDEVVAIGAAI 346 Query: 388 GAAGAVEAAFTTLACYYQKLPPTLNLDC 415 + P +L ++ Sbjct: 347 QGGVIAGEVKDVVLL--DVTPLSLGIET 372 >5M3K-C nrPDB Length = 398 Score = 36.6 bits (83), Expect = 0.024, Method: Composition-based stats. Identities = 22/138 (15%), Positives = 50/138 (36%), Gaps = 23/138 (16%) Query: 123 IGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVVSETALNFQTKGYNKVSPFFVPK 182 + A +A+ + + P+ + +V +V + K+ P + Sbjct: 1 MCARRVAIVSAAYTPKPGSSRVRQ-------TFKEMIVESAYKALKD---AKMHPREIQA 50 Query: 183 ILVNMAAGQVSIRYKLKGPNHA-----------VSTA-CTTGAHAVGDSFRFIAHGDADV 230 + +S Y GP + +STA CT+ + + + +A G+ D+ Sbjct: 51 VAYGYHGEGIS-EYGGLGPTISDALGISPAPTFMSTANCTSSSVSFQMGHQMVASGEYDI 109 Query: 231 MVAGGTDSCISPLSLAGF 248 ++ GG + + A + Sbjct: 110 VLCGGFEKMTDHFNYAEY 127 >5BNS-A nrPDB Length = 317 Score = 35.4 bits (80), Expect = 0.058, Method: Composition-based stats. Identities = 22/114 (19%), Positives = 37/114 (32%), Gaps = 23/114 (20%) Query: 188 AAGQVSIRYKLKG-PNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDSCISPLSLA 246 AA Q+ +KG P V+ AC +A+ + +++ G + G+D Sbjct: 90 AACQIQSMLGIKGCPAFDVAAACAGFTYALSVADQYVKSGAVKYALVVGSDVL------- 142 Query: 247 GFSRARALSTNSDPKLACRPFHPKRDGFVMGEGAAVLVLEEYEHAVQRRARIYA 300 C P + G+GA VL E ++A Sbjct: 143 --------------ARTCDPTDRGTI-IIFGDGAGAAVLAASEEPGIISTHLHA 181 >1UB7-A nrPDB Length = 322 Score = 35.0 bits (79), Expect = 0.068, Method: Composition-based stats. Identities = 34/186 (18%), Positives = 58/186 (31%), Gaps = 19/186 (10%) Query: 181 PKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDSCI 240 P L A V R+ LK + + C +A+ + + G A ++A G ++ Sbjct: 82 PDALFPDTAALVQARFGLKAFAYDLLAGCPGWIYALAQAHALVEAGLAQKVLAVGAEALS 141 Query: 241 SPLSLAG------FSRARALSTNSDPKLAC--RPFHPKRDGFVMGEGAAVLVLEEYEHAV 292 + F + + R F DG E V Sbjct: 142 KIIDWNDRATAVLFGDGGGAAVVGKVREGYGFRSFVLGADGTGAKELYHACVAPRLPDGT 201 Query: 293 QRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGVQPEEISYINAHATST 352 + R+Y ++G A L + + AG+ PE+I H + Sbjct: 202 SMKNRLY-------MNGREVFKFAVRVMNTATLEAI----EKAGLTPEDIRLFVPHQANL 250 Query: 353 PLGDAA 358 + DAA Sbjct: 251 RIIDAA 256 >5LNQ-A nrPDB Length = 457 Score = 34.3 bits (77), Expect = 0.11, Method: Composition-based stats. Identities = 20/103 (19%), Positives = 38/103 (36%), Gaps = 12/103 (11%) Query: 152 MGMIPLEVVSET-------ALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHA 204 G+ E + + F ++G + P + + A + + YK P Sbjct: 80 SGLSGREGIVDQVVVGNFLGELFSSQG--HLGPAAIGSLTYGQAGSKNPLMYK---PAMR 134 Query: 205 VSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDSCISPLSLAG 247 V A +G AV + + G AD+ +A G + + + G Sbjct: 135 VEGAAASGGLAVISAMNALKSGSADITLAVGVEVQTTASARVG 177 >6HRV-A nrPDB Length = 421 Score = 33.9 bits (76), Expect = 0.15, Method: Composition-based stats. Identities = 29/150 (19%), Positives = 43/150 (28%), Gaps = 45/150 (30%) Query: 277 GEGAAVLVLEEYEHAVQRRARIYA-EVLGYGLSGD--------------AGHITAPDPEG 321 +GA VL + A E++ + D +T E Sbjct: 229 SDGAGAAVLASESFVRRNGLEKKAVEIVAQEMVTDLSTTFEENSCMKMVGYDMTRLAAE- 287 Query: 322 EGALRCMAAALKDAGVQPEEISYINAHATST-------------PLGDAAENKAIKHLFK 368 AGV+P ++ I H + P G A E I Sbjct: 288 --------RCYDTAGVKPSDVDVIELHDCFSANELITYEALGLCPEGKAGEL--IDR--G 335 Query: 369 DHAYA----LAVSSTKGATGHLLGAAGAVE 394 D+ Y + S + GH LGA G + Sbjct: 336 DNTYGGKWVINPSGGLISKGHPLGATGLAQ 365 Score = 33.5 bits (75), Expect = 0.21, Method: Composition-based stats. Identities = 17/52 (32%), Positives = 27/52 (51%), Gaps = 3/52 (5%) Query: 190 GQVSIRY--KLKG-PNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDS 238 GQ +I + L G P V+ C+TG+ A+ + I G AD ++A G + Sbjct: 73 GQRAIYHSLGLSGIPIINVNNNCSTGSTALFMGRQLIQGGLADCVLALGFEK 124 >5BQS-A nrPDB Length = 323 Score = 33.5 bits (75), Expect = 0.18, Method: Composition-based stats. Identities = 36/205 (17%), Positives = 73/205 (35%), Gaps = 55/205 (26%) Query: 181 PKILVNMAAGQVSIRYKL-KGPNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDSC 239 P ++ A +V K ++ AC+ A+ + +FIA G + G+++ Sbjct: 82 PDSMMPSTAARVQANIGANKAFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSET- 140 Query: 240 ISPLSLAGFSRARALSTNSDPKLACRPFHPKRDGFVMGEGAAVLVLE--EYEHAVQ---- 293 LS D + + + G+GA ++LE E EH + Sbjct: 141 --------------LSKAVD-------WSDRSTAVLFGDGAGGVLLEASEQEHFLAESLN 179 Query: 294 -RRARIYAEVLGYGLSGDAGHITAPDPEGEGA-------------------LRCMAAALK 333 +R +E L YG SG + +P + E A + + + Sbjct: 180 SDGSR--SECLTYGHSG----LHSPFSDQESADSFLKMDGRTVFDFAIRDVAKSIKQTID 233 Query: 334 DAGVQPEEISYINAHATSTPLGDAA 358 ++ ++ ++ Y+ H + + D Sbjct: 234 ESPIEVTDLDYLLLHQANDRILDKM 258 >4DFE-A nrPDB Length = 333 Score = 33.1 bits (74), Expect = 0.23, Method: Composition-based stats. Identities = 37/191 (19%), Positives = 62/191 (32%), Gaps = 44/191 (23%) Query: 176 SPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGG 235 +P FV + ++ IR G V C+ A+AV + FI G + G Sbjct: 96 TPDFVFPSTACLLQNKLGIRN--HGAAFDVQAVCSGFAYAVATADSFIRSGQHRTALVIG 153 Query: 236 TDSCISPLSLAGFSRARALSTNSDPKLACRPFH-PKRDGFVM-GEGAAVLVLEEYE---- 289 ++ R R V+ G+GA ++L+ + Sbjct: 154 AETF------------------------SRILDFKDRTTCVLFGDGAGAVILQASDEPGV 189 Query: 290 -----HAVQRRARIY---AEVLGYGLSGDAG-HITAPDPEGEG---ALRCMAAALKDAGV 337 HA + I V G +SG A H+ + AL+ A + Sbjct: 190 LASALHADGSHSNILCTPGNVNGGVVSGSAFLHMDGQAVFKLAVNVLEKVAVEALEKANL 249 Query: 338 QPEEISYINAH 348 E+I ++ H Sbjct: 250 SAEQIDWLIPH 260 >5VXG-A nrPDB Length = 358 Score = 33.1 bits (74), Expect = 0.23, Method: Composition-based stats. Identities = 16/89 (17%), Positives = 32/89 (35%), Gaps = 7/89 (7%) Query: 201 PNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALSTNSDP 260 V+ AC + + + R + G+ D + ++ A + L + P Sbjct: 135 MTFDVANACLAFINGMDIAARMLERGEIDYALVVDGET-------ANLVYEKTLERMTSP 187 Query: 261 KLACRPFHPKRDGFVMGEGAAVLVLEEYE 289 + F + +G GAA +V+ E Sbjct: 188 DVTEEEFRNELAALTLGCGAAAMVMARSE 216 >1D4E-A nrPDB Length = 572 Score = 33.1 bits (74), Expect = 0.26, Method: Composition-based stats. Identities = 21/93 (22%), Positives = 33/93 (35%), Gaps = 8/93 (8%) Query: 275 VMGEGAAVLVLEEYEHAVQRR--ARIYAEVLGYGLSGDAGHITA-PDPEGEGALRCMAAA 331 V GE V++ + A+ V Y T P G+G + Sbjct: 294 VKGEYTGYYVIKADAVVIAAGGFAKNNERVSKYDPKLKGFKATNHPGATGDGLDVALQ-- 351 Query: 332 LKDAGVQPEEISYINAHATSTPLGDAAENKAIK 364 AG ++ YI AH T +P G +A++ Sbjct: 352 ---AGAATRDLQYIQAHPTYSPAGGVMITEAVR 381 >4YLT-A nrPDB Length = 316 Score = 32.7 bits (73), Expect = 0.34, Method: Composition-based stats. Identities = 20/115 (17%), Positives = 39/115 (33%), Gaps = 27/115 (23%) Query: 189 AGQVSIRYKLK-GPNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDSCISPLSLAG 247 A QV +K + ++ AC +A+ + +++ G + G+D Sbjct: 91 ACQVQRMLGIKDAASFDLAAACAGFTYALSVADQYVKSGAVKHAIVIGSDVL-------- 142 Query: 248 FSRARALSTNSDPKLACRPFHPKRDGFVM--GEGAAVLVLEEYEHAVQRRARIYA 300 R P+ G ++ G+GA +VL E ++A Sbjct: 143 ----------------SRALDPEDRGTIILFGDGAGAVVLGASEQPGIMSTHLHA 181 >3IL7-A nrPDB Length = 313 Score = 32.3 bits (72), Expect = 0.41, Method: Composition-based stats. Identities = 46/287 (16%), Positives = 94/287 (32%), Gaps = 84/287 (29%) Query: 121 MAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVVSETALNFQTKGYNKVSPFFV 180 +A A+ A+ D+G P+ D VA G +P V+ Q + Sbjct: 54 LAYEASVKAIADAGIQPE---DIDMIIVATATGDMPFPTVAN---MLQER---------- 97 Query: 181 PKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDSCI 240 + G+V+ + AC+ +++ + +++ GD ++ G D Sbjct: 98 ------LGTGKVA--------SMDQLAACSGFMYSMITAKQYVQSGDYHNILVVGADK-- 141 Query: 241 SPLSLAGFSRARALSTNSDPKLACRPFHPKRDGFVMGEGAAVLVLEEYEHAVQRRARIYA 300 LS +D + G+GA +++ E R Sbjct: 142 -------------LSKITDLTDRSTA-------VLFGDGAGAVIIGEVS--EGRG----- 174 Query: 301 EVLGYGLSGD---AGHITAPDPEGEG----------ALRCMAAA----LKDAGVQPEEIS 343 ++ Y + D H+ G+ A+R M A ++ A + ++I Sbjct: 175 -IISYEMGSDGTGGKHLYLDKDTGKLKMNGREVFKFAVRIMGDASTRVVEKANLTSDDID 233 Query: 344 YINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAA 390 H + + ++A + ++VS K G+ A+ Sbjct: 234 LFIPHQANIRIMESA-----RERLGISKDKMSVSVNKY--GNTSAAS 273 >3IL4-A nrPDB Length = 320 Score = 32.3 bits (72), Expect = 0.44, Method: Composition-based stats. Identities = 29/173 (16%), Positives = 53/173 (30%), Gaps = 38/173 (21%) Query: 202 NHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALSTNSDPK 261 +S AC+ +A+ + + + G + G ++ FS+ Sbjct: 105 AFDISAACSGFVYALSMAEKLVLSGRYQTGLVIGGET---------FSKM---------- 145 Query: 262 LACRPFHPKRDGFVMGEGAAVLVLEEYEHA-------VQRRARIYAEVLGYGLSGDAG-- 312 + + + G+GAA +++E E R A GY ++ Sbjct: 146 ---LDWTDRSTAVLFGDGAAGVLIEAAETPHFLNEKLQADGQRWTALTSGYTINESPFYQ 202 Query: 313 -HITAPDPEGEGALRCMAAALKDAG------VQPEEISYINAHATSTPLGDAA 358 H A A+KD V E + Y+ H S + D Sbjct: 203 GHKQASKTLQMEGRSIFDFAIKDVSQNILSLVTDETVDYLLLHQASVRIIDKI 255 >3H76-A nrPDB Length = 359 Score = 32.0 bits (71), Expect = 0.56, Method: Composition-based stats. Identities = 11/57 (19%), Positives = 22/57 (38%) Query: 312 GHITAPDPEGEGALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFK 368 H+ + A++ AG+ PE+I + + S D ++ I+ L Sbjct: 66 YHVEPEQAVSALMVPAARQAIEAAGLLPEDIDLLLVNTLSPDHHDPSQACLIQPLLG 122 >4Q4K-A nrPDB Length = 357 Score = 32.0 bits (71), Expect = 0.63, Method: Composition-based stats. Identities = 21/115 (18%), Positives = 40/115 (34%), Gaps = 2/115 (1%) Query: 311 AGHITAPDPEGEGALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDH 370 + H AP + AL+ + + PEE + + A + E + +F+ Sbjct: 131 SFHFGAPPRDQVRALQAVGIRVLVCATTPEEAALVEAAGADAVVAQGIEAGGHRGVFEPE 190 Query: 371 AYALAVSSTKGATGHLLGAAGAVEAAFTTLACYYQKLPPTLNLDCSEPEFDLNYV 425 A+ + A LL A G++ + + L L S + +V Sbjct: 191 RGDAAIGTL--ALVRLLAARGSLPVVAAGGIMDGRGIRAALELGASAVQMGTAFV 243 >3IL3-A nrPDB Length = 323 Score = 31.6 bits (70), Expect = 0.74, Method: Composition-based stats. Identities = 20/103 (19%), Positives = 35/103 (33%), Gaps = 26/103 (25%) Query: 200 GPNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALSTNSD 259 + ++ ACT +A+ + +FI G + G+D Sbjct: 110 AISFDLAAACTGFVYALSVADQFIRAGKVKKALVIGSD---------------------- 147 Query: 260 PKLACRPFHP-KRDGFVM-GEGAAVLVLEEYEHAVQRRARIYA 300 L R R V+ G+GA ++LE E ++A Sbjct: 148 --LNSRKLDETDRSTVVLFGDGAGAVILEASEQEGIISTHLHA 188 >6EC3-A nrPDB Length = 471 Score = 31.6 bits (70), Expect = 0.75, Method: Composition-based stats. Identities = 17/138 (12%), Positives = 42/138 (30%), Gaps = 10/138 (7%) Query: 59 THLVWDRLIGG---ESGIVSLVGE-EYKSIPCSVAAYVPRGSDEGQFNEQNFVSKSDIKS 114 W L +GI ++ Y + E Q D++ Sbjct: 156 VREPWALLKDAARVSAGIYLSTHYWGSSDGLETLDGYSVKHVREEHPEPQARGLSVDVRW 215 Query: 115 MSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVVSETALNFQTKGYNK 174 + ++ A A++++G+ + + + ++ + F+ G+ Sbjct: 216 LDRASLFA------ALENAGFVEIEVLHERTSAEVCDIVVVGRARLGAQIRRFREDGFVN 269 Query: 175 VSPFFVPKILVNMAAGQV 192 P F + + AG + Sbjct: 270 AGPVFADDTIARLKAGAI 287 >3IP8-A nrPDB Length = 248 Score = 31.2 bits (69), Expect = 0.87, Method: Composition-based stats. Identities = 35/176 (19%), Positives = 61/176 (34%), Gaps = 21/176 (11%) Query: 139 SEADQVATGVAIGMGMIP-----LEVVSETALNFQTKGYNKVSPFFVPKILVNMAAGQVS 193 + +A+G+ +G +E V + A Q +G VS AA + Sbjct: 29 PDLPFIASGLGLGSVTPEGYDAVIESVVDHARRLQKQGAAVVSLMGTSLSFYRGAAFNAA 88 Query: 194 IRYKLKG----PNHAVSTACTTGAHAVGDSFRFIAHGDADVM----VAGGTDSCISP--- 242 + ++ P +STA G A+G +A D + A + + P Sbjct: 89 LTVAMREATGLPCTTMSTAVLNGLRALGVRRVALATAYIDDVNERLAAFLAEESLVPTGC 148 Query: 243 --LSLAGFSRARALSTNSDPKLACRPFHP--KRDGFVMGEGAAVLVLEEYEHAVQR 294 L + G + T + L R F DG ++ G +L L+ +R Sbjct: 149 RSLGITGVEAMARVDTATLVDLCVRAFEAAPDSDGILLSCG-GLLTLDAIPEVERR 203 >4O5M-A nrPDB Length = 390 Score = 31.2 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 18/92 (19%), Positives = 31/92 (33%), Gaps = 8/92 (8%) Query: 152 MGMIPLEVVSETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHA--VSTAC 209 +V+ A + G +S F + K + Q + ++G N V C Sbjct: 166 TNGPDADVLVVYAKTDLSAGPRGISAFIIEKGFKGFSTAQKLDKLGMRGSNTCELVFEDC 225 Query: 210 TTGAHAV----GDSFRFIAHG--DADVMVAGG 235 A + G + G V++AGG Sbjct: 226 EVPAENLLGTEGKGVNVLMSGLDYERVVLAGG 257 >1W66-A nrPDB Length = 232 Score = 30.8 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 16/63 (25%), Positives = 23/63 (36%) Query: 222 FIAHGDADVMVAGGTDSCISPLSLAGFSRARALSTNSDPKLACRPFHPKRDGFVMGEGAA 281 + AD VAGG D+ + A ++ R T+ P R G + G Sbjct: 29 QLQRELADARVAGGADTLLLLEHPAVYTAGRRTETHERPIDGTPVVDTDRGGKITWHGPG 88 Query: 282 VLV 284 LV Sbjct: 89 QLV 91 >1MZJ-A nrPDB Length = 339 Score = 30.8 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 25/178 (14%), Positives = 51/178 (28%), Gaps = 52/178 (29%) Query: 108 SKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVVSETALNF 167 S+ + + +M + A+ A++ +G P V + + + Sbjct: 50 SRRIAEPDETIQVMGVAASRRALEHAGVDPAEID-----LVVVSTMTNFVHTPPLSVAIA 104 Query: 168 QTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSFRFIAHGD 227 G + F +S AC HA+ + + G Sbjct: 105 HELGADNAGGFD-------------------------LSAACAGFCHALSIAADAVESGG 139 Query: 228 ADVMVAGGTDSCISPLSLAGFSRARALSTNSDPKLACRPFHPKRDGFVMGEGAAVLVL 285 + ++ T+ + L R+LS F+ G+GA V+ Sbjct: 140 SRHVLVVATERMTDVIDL----ADRSLS------------------FLFGDGAGAAVV 175 Score = 28.9 bits (63), Expect = 5.5, Method: Composition-based stats. Identities = 21/75 (28%), Positives = 31/75 (41%), Gaps = 2/75 (2%) Query: 323 GALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFK-DHAYALAVSSTKG 381 + AL+ AGV P EI + + + + AI H D+A +S+ Sbjct: 63 MGVAASRRALEHAGVDPAEIDLVVVSTMTNFVHTPPLSVAIAHELGADNAGGFDLSAACA 122 Query: 382 ATGHLLG-AAGAVEA 395 H L AA AVE+ Sbjct: 123 GFCHALSIAADAVES 137 >4KTO-A nrPDB Length = 410 Score = 30.4 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 18/92 (19%), Positives = 34/92 (36%), Gaps = 8/92 (8%) Query: 152 MGMIPLEVVSETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHA--VSTAC 209 +V+ A G ++ F V K +AGQ + ++G N + + T C Sbjct: 186 TNGPDADVLVVYAKTDPAAGPRGITAFLVEKAFPGFSAGQKLDKLGMRGSNTSELIFTDC 245 Query: 210 TTGAHA----VGDSFRFIAHG--DADVMVAGG 235 VG+ + + G V+++ G Sbjct: 246 EVPEENVLGGVGEGVKVLMSGLDYERVVLSAG 277 >6ET0-A nrPDB Length = 365 Score = 30.4 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 8/22 (36%), Positives = 12/22 (54%) Query: 327 CMAAALKDAGVQPEEISYINAH 348 M AL+ AG+ ++I Y H Sbjct: 265 AMRRALEKAGLGSDDIDYFVFH 286 >3LS2-A nrPDB Length = 280 Score = 30.4 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 22/91 (24%), Positives = 29/91 (31%), Gaps = 25/91 (27%) Query: 314 ITAPDPEGEGALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYA 373 I APD G P E SY A + A F + Y Sbjct: 78 IVAPDTSPRGDNV------------PNEDSYDFAQGAGFYVN--ATQAPYNTHFNMYDYV 123 Query: 374 L-----------AVSSTKGATGHLLGAAGAV 393 + V+STK +GH +G GA+ Sbjct: 124 VNELPALIEQHFPVTSTKAISGHSMGGHGAL 154 >3V7I-A nrPDB Length = 413 Score = 30.0 bits (66), Expect = 2.0, Method: Composition-based stats. Identities = 21/90 (23%), Positives = 30/90 (33%), Gaps = 2/90 (2%) Query: 279 GAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGA--LRCMAAALKDAG 336 GAA L Q R A + S TAP E A R AL+ AG Sbjct: 94 GAAREALVRDGFTEQDANRAIAALKAVPASQTVQERTAPAWEAVQAYGERAARGALQIAG 153 Query: 337 VQPEEISYINAHATSTPLGDAAENKAIKHL 366 + ++ + ++TP + L Sbjct: 154 LDVADVDCLITSNSTTPALPGLDVALANRL 183 >4NQ3-A nrPDB Length = 356 Score = 30.0 bits (66), Expect = 2.3, Method: Composition-based stats. Identities = 23/131 (17%), Positives = 43/131 (32%), Gaps = 2/131 (1%) Query: 314 ITAPDPEGEGALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYA 373 + + E GA + LK G+ + A A DA + I + + Sbjct: 163 MRVKEAEARGATTATSDTLKSMGLSRGASALGIALALGEVAEDALSDAVICADYGLWSAR 222 Query: 374 LAVSSTKGATGHLLGAAGAVEAAFTTLACYYQKLPPTLNLDCSEPEFDLNYVPLKAQEWK 433 + SS GH + G E LA + + +++ + L+ + +A E Sbjct: 223 ASCSSGIELLGHEIVVLGMSEGWSGPLAIAHGVMADAIDVT--PVKAALSALGAEAGEAT 280 Query: 434 TEKRFIGLTNS 444 + S Sbjct: 281 IVLAKAEPSRS 291 >3MKV-A nrPDB Length = 426 Score = 29.6 bits (65), Expect = 2.9, Method: Composition-based stats. Identities = 30/171 (17%), Positives = 52/171 (30%), Gaps = 25/171 (14%) Query: 210 TTGAHAVGDSFRF-IAHG--DADVMVAGGTDSCISPLSLAGFSRARALSTNSDPKLACRP 266 G V + R + G +M +GG S P+ + G+S D A Sbjct: 171 ADGVDEVRRAVREELQMGADQIKIMASGGVASPTDPVGVFGYS--------EDEIRAIVA 222 Query: 267 FHPKRDGFVMGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALR 326 R +V+ A+ R R + +G D G + Sbjct: 223 EAQGRGTYVLAHAYT-------PAAIARAVRCGVRTIEHGNLIDDETARLVAEHGAYVVP 275 Query: 327 ------CMAAALKDAGVQPEEISYI-NAHATSTPLGDAAENKAIKHLFKDH 370 +A+ + G+ PE I+ I + H + + +K F Sbjct: 276 TLVTYDALASEGEKYGLPPESIAKIADVHGAGLHSIEIMKRAGVKMGFGTD 326 >4V6K-BO nrPDB Length = 129 Score = 29.3 bits (64), Expect = 3.6, Method: Composition-based stats. Identities = 20/78 (25%), Positives = 29/78 (37%), Gaps = 3/78 (3%) Query: 197 KLKGPNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAG---GTDSCISPLSLAGFSRARA 253 +G + A A D+ + + +VMV G G +S I L+ AGF Sbjct: 51 GFRGSRKSTPFAAQVAAERCADAVKEYGIKNLEVMVKGPGPGRESTIRALNAAGFRITNI 110 Query: 254 LSTNSDPKLACRPFHPKR 271 P CRP +R Sbjct: 111 TDVTPIPHNGCRPPKKRR 128 >2WOQ-A nrPDB Length = 337 Score = 28.9 bits (63), Expect = 4.4, Method: Composition-based stats. Identities = 15/68 (22%), Positives = 25/68 (36%), Gaps = 18/68 (26%) Query: 270 KRDGFVMGEGA-AVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCM 328 DG+V+ + + VLV + HA + AP +G + + Sbjct: 143 DDDGYVLNDVSIDVLVRQALSHAEA-----------------GAQVVAPSDMMDGRIGAI 185 Query: 329 AAALKDAG 336 AL+ AG Sbjct: 186 REALESAG 193 >4YUC-A nrPDB Length = 335 Score = 28.9 bits (63), Expect = 4.5, Method: Composition-based stats. Identities = 11/57 (19%), Positives = 21/57 (36%), Gaps = 8/57 (14%) Query: 323 GALRCMAAALKDAGVQPEEISY-INAHAT---STPLGDAAENKAIKHLFKDHAYALA 375 A++DAG++ E+I INA + + P G ++ + Sbjct: 61 MGAEAAKEAVRDAGLKLEDIDLIINASGSPEQAVPDGGPL----VQRELGLGRSGVP 113 >1E9Y-B nrPDB Length = 569 Score = 28.9 bits (63), Expect = 4.6, Method: Composition-based stats. Identities = 28/155 (18%), Positives = 53/155 (34%), Gaps = 5/155 (3%) Query: 294 RRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGVQPEEISYINAHATSTP 353 R A Y+ LG+ G+A + + + E +D G P I++ A Sbjct: 184 RAAEEYSMNLGFLAKGNASNDASLADQIEAGAIGFK-IHEDWGTTPSAINHALDVADKYD 242 Query: 354 LGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFTTLACYYQKLP----P 409 + A + A++ T H GA G +A + LP P Sbjct: 243 VQVAIHTDTLNEAGCVEDTMAAIAGRTMHTFHTEGAGGGHAPDIIKVAGEHNILPASTNP 302 Query: 410 TLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNS 444 T+ + ++ + + + K+ K + +S Sbjct: 303 TIPFTVNTEAEHMDMLMVCHHKDKSIKEDVQFADS 337 >5YA1-A nrPDB Length = 540 Score = 28.9 bits (63), Expect = 4.8, Method: Composition-based stats. Identities = 11/26 (42%), Positives = 17/26 (65%) Query: 322 EGALRCMAAALKDAGVQPEEISYINA 347 + A CM AL +AG+ PE I+ ++A Sbjct: 74 QLACECMRQALHNAGIAPEYIAAVSA 99 >3LM6-A nrPDB Length = 346 Score = 28.9 bits (63), Expect = 4.8, Method: Composition-based stats. Identities = 31/199 (15%), Positives = 62/199 (31%), Gaps = 43/199 (21%) Query: 186 NMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDSCIS---- 241 N+ A V+ K+ P + AC+T V + + G A +A + + Sbjct: 89 NVTANYVARHLKI--PFLCMFGACSTSMETVAVASALVDGGFAKRALAATSSHNATAERQ 146 Query: 242 ---PLSLAGFSRARALSTNSDPKLACRPFHPKRDGFVMGEGAAVLVLEEYEHAVQRRARI 298 P G A ST + G+ +V+ + +Q + Sbjct: 147 FRYPTEYGGQKPDTATSTVT--------------------GSGAVVISQTPGDIQITSAT 186 Query: 299 YAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGVQPEEISYI---NAHATSTPLG 355 +V G++ D + A + KD ++ I + +P+ Sbjct: 187 VGKVSDLGIT-DPFDM--GSAMAPAAADTIKQHFKDLNRTADDYDLILTGDLSGVGSPI- 242 Query: 356 DAAENKAIKHLFKDHAYAL 374 +K + K+ Y + Sbjct: 243 -------VKDILKEDGYPV 254 >5BY7-A nrPDB Length = 360 Score = 28.9 bits (63), Expect = 5.2, Method: Composition-based stats. Identities = 13/58 (22%), Positives = 24/58 (41%), Gaps = 1/58 (1%) Query: 181 PKILVNMAAGQVSIRYKLKG-PNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTD 237 P L+ A V+ R + G P + + + C+ A+ + + G A + G D Sbjct: 113 PDRLMPTTATVVADRLGIDGVPAYQLQSGCSGAVQALAVTRSLLLGGTARTALVLGGD 170 >2R9Z-A nrPDB Length = 463 Score = 28.5 bits (62), Expect = 6.1, Method: Composition-based stats. Identities = 23/93 (24%), Positives = 31/93 (33%), Gaps = 10/93 (10%) Query: 189 AGQVSIRYKLK--GPNHAVSTACTT------GAHAVGDSFRFIAHGDADVMVAGGTDSCI 240 +RY L GP A+ C G H +GD + G A + G T + Sbjct: 371 TSFTPMRYALNEHGPKTAMKLVCAGPEQRVVGVHVIGDGADEMLQGFAVAVKMGATKADF 430 Query: 241 SPLSLAGFSRARALSTNSDPKLACRPFHPKRDG 273 A L T +P RP P +G Sbjct: 431 DNTVAIHPGSAEELVTLKEPVR--RPGDPLPEG 461 >2DKD-A nrPDB Length = 544 Score = 28.5 bits (62), Expect = 6.7, Method: Composition-based stats. Identities = 13/93 (13%), Positives = 31/93 (33%), Gaps = 3/93 (3%) Query: 48 GIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDEGQFN---EQ 104 G+ +V PLG W++ + + + S+ + + + + Sbjct: 74 GVKVVDPLGSMLESSWEKYATDLANASPSPSNDSEGEKNSLVEVIKNLVSDLKIDLSIPA 133 Query: 105 NFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHP 137 N V D + S MA ++ ++ + Sbjct: 134 NVVIARDSRESSPALSMATIDGFQSVPNTKYQD 166 >6ESQ-I nrPDB Length = 349 Score = 28.1 bits (61), Expect = 7.5, Method: Composition-based stats. Identities = 12/28 (42%), Positives = 14/28 (50%), Gaps = 1/28 (3%) Query: 288 YEHAVQRRARIYAEVLGYGLSGDAGHIT 315 +HA + ARI A G G DA IT Sbjct: 284 LDHAEE-GARILAVSYGSGAGSDAFDIT 310 >3HMU-A nrPDB Length = 472 Score = 28.1 bits (61), Expect = 8.3, Method: Composition-based stats. Identities = 12/95 (12%), Positives = 34/95 (35%), Gaps = 4/95 (4%) Query: 325 LRCMAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAY--ALAVSSTKGA 382 + +A A K A + P +++++ + D + ++ +++ + S K A Sbjct: 99 VPAIALAQKLAELAPGDLNHVFFAGGGSEAND-TNIRMVRTYWQNKGQPEKTVIISRKNA 157 Query: 383 TGHLLGAAGAVEAAFTTLACYYQKLPPTLNLDCSE 417 H A + + +P +++ Sbjct: 158 Y-HGSTVASSALGGMAGMHAQSGLIPDVHHINQPN 191 >3HQ1-A nrPDB Length = 644 Score = 28.1 bits (61), Expect = 8.8, Method: Composition-based stats. Identities = 16/52 (30%), Positives = 18/52 (34%), Gaps = 3/52 (5%) Query: 315 TAPDPEGEGALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHL 366 T G G L AL D G + Y HA S GD A+ A Sbjct: 525 TEISGSGNGPLAAFVHALADVGFDVAVLDYYE-HAMS--AGDDAQAAAYVEA 573 >5YO9-A nrPDB Length = 371 Score = 28.1 bits (61), Expect = 9.5, Method: Composition-based stats. Identities = 14/75 (18%), Positives = 27/75 (36%), Gaps = 2/75 (2%) Query: 324 ALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGAT 383 + A+++AGV E+I + ++ A I+ YA ++ A Sbjct: 102 GVIAAKQAMENAGVTAEDIDVVILACSNMQRAYPAVAIEIQSALGIQGYAYDMNVAASAA 161 Query: 384 GHLLGAAGAVEAAFT 398 G A +A + Sbjct: 162 --TFGLKQAADAIRS 174 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.134 0.355 Lambda K H 0.267 0.0413 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,035,308 Number of Sequences: 36641 Number of extensions: 685765 Number of successful extensions: 2757 Number of sequences better than 10.0: 122 Number of HSP's better than 10.0 without gapping: 121 Number of HSP's successfully gapped in prelim test: 51 Number of HSP's that attempted gapping in prelim test: 2249 Number of HSP's gapped (non-prelim): 251 length of query: 459 length of database: 10,336,785 effective HSP length: 100 effective length of query: 359 effective length of database: 6,672,685 effective search space: 2395493915 effective search space used: 2395493915 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 61 (28.1 bits)