BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9NUI1 (292 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4FC7-A nrPDB 565 e-162 1YXM-A nrPDB 158 2e-39 1W73-A nrPDB 137 5e-33 3FTP-A nrPDB 129 1e-30 3AUT-A nrPDB 118 3e-27 4IS3-A nrPDB 117 6e-27 1GEE-A nrPDB 114 5e-26 2PNF-A nrPDB 111 3e-25 4JRO-A nrPDB 109 1e-24 3RSH-A nrPDB 108 3e-24 5ITV-A nrPDB 107 4e-24 2EW8-A nrPDB 107 7e-24 1AHH-A nrPDB 105 3e-23 5CDY-A nrPDB 102 3e-22 4E6P-A nrPDB 101 3e-22 1K2W-A nrPDB 100 1e-21 3WOH-A nrPDB 99 2e-21 6CI9-A nrPDB 99 3e-21 4MOW-A nrPDB 98 3e-21 3OEC-A nrPDB 98 4e-21 1Q7C-A nrPDB 97 7e-21 2HQ1-A nrPDB 97 1e-20 4Z9Y-A nrPDB 97 1e-20 4M8S-A nrPDB 96 1e-20 2C07-A nrPDB 96 2e-20 4BO1-A nrPDB 96 2e-20 2HSD-A nrPDB 96 2e-20 4NBV-A nrPDB 96 3e-20 4NBT-A nrPDB 95 4e-20 2UVD-A nrPDB 94 7e-20 2CFC-A nrPDB 93 1e-19 3U5T-A nrPDB 93 1e-19 3OSU-A nrPDB 92 2e-19 4CQM-B nrPDB 92 3e-19 2AE2-A nrPDB 91 4e-19 5VT6-A nrPDB 91 6e-19 1AE1-A nrPDB 91 6e-19 5JS6-A nrPDB 91 6e-19 5U9P-A nrPDB 90 9e-19 5T5Q-A nrPDB 90 1e-18 3OIC-A nrPDB 89 2e-18 3EMK-A nrPDB 89 2e-18 1GEG-A nrPDB 89 2e-18 4IIN-A nrPDB 89 3e-18 3UF0-A nrPDB 89 3e-18 3LYL-A nrPDB 88 5e-18 4DMM-A nrPDB 88 5e-18 3EZL-A nrPDB 87 8e-18 1DOH-A nrPDB 87 1e-17 2NM0-A nrPDB 86 1e-17 3O4R-A nrPDB 86 1e-17 4K6F-A nrPDB 86 2e-17 5OJG-A nrPDB 85 3e-17 3D3W-A nrPDB 84 8e-17 2O23-A nrPDB 83 1e-16 3T7C-A nrPDB 83 1e-16 2CDH-G nrPDB 83 1e-16 4KMS-A nrPDB 83 1e-16 4RZH-A nrPDB 83 2e-16 1H5Q-A nrPDB 82 3e-16 3UN1-A nrPDB 82 4e-16 2B4Q-A nrPDB 82 4e-16 3VZS-A nrPDB 81 6e-16 4HP8-A nrPDB 80 8e-16 2ZAT-A nrPDB 80 1e-15 5EJ2-A nrPDB 80 1e-15 2PH3-A nrPDB 79 2e-15 1NFF-A nrPDB 79 2e-15 1E3W-A nrPDB 79 3e-15 3GRP-A nrPDB 79 3e-15 4AVY-A nrPDB 78 4e-15 4DBZ-A nrPDB 78 4e-15 2NWQ-A nrPDB 78 5e-15 3F9I-A nrPDB 77 8e-15 1CYD-A nrPDB 77 1e-14 5IZ4-A nrPDB 76 1e-14 5JY1-A nrPDB 75 3e-14 2FWM-X nrPDB 74 6e-14 3PXX-A nrPDB 74 9e-14 5KOI-A nrPDB 74 1e-13 3WTC-A nrPDB 73 1e-13 3WYE-A nrPDB 73 1e-13 3UVE-A nrPDB 73 2e-13 3V2G-A nrPDB 72 2e-13 4CQL-A nrPDB 72 3e-13 4RZI-B nrPDB 71 5e-13 4ALL-A nrPDB 70 1e-12 6NRP-A nrPDB 70 1e-12 3R3S-A nrPDB 70 1e-12 2Q2Q-A nrPDB 70 1e-12 1UZM-A nrPDB 70 1e-12 3V2H-A nrPDB 69 2e-12 3U4C-A nrPDB 68 4e-12 1X1T-A nrPDB 68 5e-12 4TRR-A nrPDB 68 6e-12 2YW9-A nrPDB 67 8e-12 4EGF-A nrPDB 66 2e-11 3A28-C nrPDB 65 2e-11 3GDF-A nrPDB 65 3e-11 5OVL-A nrPDB 65 3e-11 5OVJ-A nrPDB 65 3e-11 3RWB-A nrPDB 65 4e-11 5B1Y-A nrPDB 65 4e-11 2AG5-A nrPDB 65 4e-11 1O5I-A nrPDB 65 4e-11 3GRK-A nrPDB 64 5e-11 3ZV3-A nrPDB 64 8e-11 1HXH-A nrPDB 64 1e-10 5TF4-A nrPDB 64 1e-10 1ENP-A nrPDB 64 1e-10 3V8B-A nrPDB 63 1e-10 4IIV-A nrPDB 63 2e-10 5YSS-A nrPDB 62 2e-10 4CR6-A nrPDB 62 2e-10 3PPI-A nrPDB 59 2e-09 3W8F-A nrPDB 59 3e-09 4ZJU-A nrPDB 58 4e-09 1BDB-A nrPDB 58 5e-09 6CGE-A nrPDB 57 9e-09 5O3Z-A nrPDB 57 9e-09 4NK4-A nrPDB 57 1e-08 1A27-A nrPDB 57 1e-08 2BGM-A nrPDB 57 1e-08 5YCX-A nrPDB 56 2e-08 2DKN-A nrPDB 56 2e-08 2PD3-A nrPDB 55 3e-08 3O26-A nrPDB 55 4e-08 4Q9N-A nrPDB 54 6e-08 3OIG-A nrPDB 54 1e-07 4GKB-A nrPDB 53 1e-07 3OML-A nrPDB 53 1e-07 1P33-A nrPDB 53 1e-07 4NR0-A nrPDB 53 2e-07 5CFZ-A nrPDB 53 2e-07 4JQC-A nrPDB 52 3e-07 1FJH-A nrPDB 52 3e-07 3U9L-A nrPDB 52 3e-07 2P91-A nrPDB 52 3e-07 5L51-A nrPDB 52 4e-07 4J3F-A nrPDB 52 4e-07 5I9N-A nrPDB 51 5e-07 5ILO-A nrPDB 50 8e-07 2QHX-A nrPDB 49 2e-06 2BFA-A nrPDB 49 2e-06 4DA9-A nrPDB 49 3e-06 3UCF-A nrPDB 48 6e-06 4RGB-A nrPDB 47 1e-05 3K2E-A nrPDB 47 1e-05 3RKU-A nrPDB 46 1e-05 2X9N-A nrPDB 46 2e-05 2PTG-A nrPDB 44 7e-05 2O2S-A nrPDB 44 8e-05 5LCX-A nrPDB 44 8e-05 4M89-A nrPDB 44 1e-04 3E9N-A nrPDB 43 1e-04 2GDZ-A nrPDB 43 1e-04 4DRY-A nrPDB 43 1e-04 1N5D-A nrPDB 43 1e-04 3KZV-A nrPDB 42 4e-04 4HBG-A nrPDB 39 0.002 2NTV-A nrPDB 39 0.002 1UN9-A nrPDB 37 0.007 3DWF-A nrPDB 37 0.011 2HRB-A nrPDB 37 0.012 3F4B-A nrPDB 37 0.013 3BHI-A nrPDB 36 0.021 5PGZ-A nrPDB 35 0.027 4OYR-A nrPDB 34 0.084 2O2Y-A nrPDB 32 0.33 1SNY-A nrPDB 31 0.76 1KZH-A nrPDB 30 1.1 4NPH-A nrPDB 29 1.9 4Z3K-A nrPDB 29 2.9 4HWK-A nrPDB 28 3.3 2DUN-A nrPDB 28 3.9 2HTF-A nrPDB 28 3.9 2DPY-A nrPDB 28 3.9 4IQL-A nrPDB 27 9.8 >4FC7-A nrPDB Length = 277 Score = 565 bits (1456), Expect = e-162, Method: Compositional matrix adjust. Identities = 277/277 (100%), Positives = 277/277 (100%) Query: 2 AQPPPDVEGDDCLPAYRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRS 61 AQPPPDVEGDDCLPAYRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRS Sbjct: 1 AQPPPDVEGDDCLPAYRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRS 60 Query: 62 LPRVLTAARKLAGATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCP 121 LPRVLTAARKLAGATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCP Sbjct: 61 LPRVLTAARKLAGATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCP 120 Query: 122 AGALSFNAFKTVMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSA 181 AGALSFNAFKTVMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSA Sbjct: 121 AGALSFNAFKTVMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSA 180 Query: 182 KAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGN 241 KAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGN Sbjct: 181 KAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGN 240 Query: 242 KTEIAHSVLYLASPLASYVTGAVLVADGGAWLTFPNG 278 KTEIAHSVLYLASPLASYVTGAVLVADGGAWLTFPNG Sbjct: 241 KTEIAHSVLYLASPLASYVTGAVLVADGGAWLTFPNG 277 >1YXM-A nrPDB Length = 303 Score = 158 bits (400), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 90/258 (34%), Positives = 137/258 (53%), Gaps = 6/258 (2%) Query: 18 RHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAG--- 74 R P LL+ +VA +TGG +GIG I + + G + VIASR L R+ +AA +L Sbjct: 8 RSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLP 67 Query: 75 -ATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTV 133 R +P+ ++R V V L FG+I+ L+N G FL PA +S + V Sbjct: 68 PTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAV 127 Query: 134 MDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLA 193 ++ + +GTF + + +Y + ++HGG IVNI G L VH+G+A+A V +T+ LA Sbjct: 128 LETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPT-KAGFPLAVHSGAARAGVYNLTKSLA 186 Query: 194 VEWGPQNIRVNSLAPGPISGTEGLRRLGGP-QASLSTKVTASPLQRLGNKTEIAHSVLYL 252 +EW IR+N +APG I + G Q+ P +R+G E++ V +L Sbjct: 187 LEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFL 246 Query: 253 ASPLASYVTGAVLVADGG 270 SP AS++TG + DGG Sbjct: 247 LSPAASFITGQSVDVDGG 264 >1W73-A nrPDB Length = 302 Score = 137 bits (346), Expect = 5e-33, Method: Compositional matrix adjust. Identities = 92/258 (35%), Positives = 137/258 (53%), Gaps = 3/258 (1%) Query: 15 PAYRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAG 74 P + + P+ + KVAFITGGG+G+G + + G VIASR + + A +++ Sbjct: 13 PLQKAMLPPNSFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISS 72 Query: 75 ATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVM 134 TG + + DVR P V V + +K G +I+IN AAGNF+ P LS NA+KT+ Sbjct: 73 QTGNKVHAIQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTIT 132 Query: 135 DIDTSGTFNVSRVLYEKFFR-DHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLA 193 DI +GT V+ + ++ + G ++IT G V + SAKA V+AM++ LA Sbjct: 133 DIVLNGTAFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLA 192 Query: 194 VEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTAS-PLQRLGNKTEIAHSVLYL 252 EWG +R N + PGPI RL P + ++ P RLG E+A+ +L Sbjct: 193 AEWGKYGMRFNVIQPGPIKTKGAFSRL-DPTGTFEKEMIGRIPCGRLGTVEELANLAAFL 251 Query: 253 ASPLASYVTGAVLVADGG 270 S AS++ GAV+ DGG Sbjct: 252 CSDYASWINGAVIKFDGG 269 >3FTP-A nrPDB Length = 270 Score = 129 bits (325), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 93/253 (36%), Positives = 133/253 (52%), Gaps = 12/253 (4%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTV--IASRSLPRVLTAARKLAGATGRRCLPL 83 L +VA +TG GIG IA R G + + + + AA K AG GR + Sbjct: 26 LDKQVAIVTGASRGIGRAIALELARRGAMVIGTATTEAGAEGIGAAFKQAGLEGRGAV-- 83 Query: 84 SMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFN 143 ++V AV A V+ LKEFG +++L+N A A + + + V+D + F Sbjct: 84 -LNVNDATAVDALVESTLKEFGALNVLVNNAGITQDQLAMRMKDDEWDAVIDTNLKAVFR 142 Query: 144 VSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRV 203 +SR + + GG IVNIT+ +G+ G QV+ +AKA V MTR LA E G + I V Sbjct: 143 LSRAVLRPMMKARGGRIVNITSVVGSAGNPGQVNYAAAKAGVAGMTRALAREIGSRGITV 202 Query: 204 NSLAPGPISG--TEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVT 261 N +APG I T+GL PQ + T PL RLG+ +IAH+V +LASP A Y+T Sbjct: 203 NCVAPGFIDTDMTKGL-----PQEQQTALKTQIPLGRLGSPEDIAHAVAFLASPQAGYIT 257 Query: 262 GAVLVADGGAWLT 274 G L +GG +++ Sbjct: 258 GTTLHVNGGMFMS 270 >3AUT-A nrPDB Length = 269 Score = 118 bits (295), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 79/248 (31%), Positives = 125/248 (50%), Gaps = 6/248 (2%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L+DKV ITGG +G+G +A F + VI + A+K G + + + Sbjct: 13 LKDKVVVITGGSTGLGRAMAVRFGQEEAKVVINYYNNEEEALDAKKEVEEAGGQAIIVQG 72 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 DV V+ V A+KEFG +D++IN A P+ LS + + V+D + +G F S Sbjct: 73 DVTKEEDVVNLVQTAIKEFGTLDVMINNAGVENPVPSHELSLDNWNKVIDTNLTGAFLGS 132 Query: 146 RVLYEKFFR-DHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVN 204 R + F D G ++N+++ L VH ++K + MT LA+E+ P+ IRVN Sbjct: 133 REAIKYFVENDIKGNVINMSSVHEMIPWPLFVHYAASKGGMKLMTETLALEYAPKGIRVN 192 Query: 205 SLAPGPISGTEGLRRLGGP--QASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTG 262 ++ PG ++ + P +A + + + P+ +G E+A +LAS ASYVTG Sbjct: 193 NIGPGAMNTPINAEKFADPVQRADVESMI---PMGYIGKPEEVAAVAAFLASSQASYVTG 249 Query: 263 AVLVADGG 270 L ADGG Sbjct: 250 ITLFADGG 257 >4IS3-A nrPDB Length = 268 Score = 117 bits (293), Expect = 6e-27, Method: Compositional matrix adjust. Identities = 84/247 (34%), Positives = 126/247 (51%), Gaps = 4/247 (1%) Query: 24 DLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGAT-GRRCLP 82 +L++DKV ITGG GIGF A+IF+ +G I + V TA +L L Sbjct: 21 NLVQDKVTIITGGTRGIGFAAAKIFIDNGAKVSIFGETQEEVDTALAQLKELYPEEEVLG 80 Query: 83 LSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTF 142 + D+ + AVMAAV Q +++GR+D++IN A +S FK +MDI+ +G F Sbjct: 81 FAPDLTSRDAVMAAVGQVAQKYGRLDVMINNAGITSNNVFSRVSEEEFKHIMDINVTGVF 140 Query: 143 NVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIR 202 N + Y+ GVI+N + G G V ++KA+V +T L E +NIR Sbjct: 141 NGAWCAYQCMKDAKKGVIINTASVTGIFGSLSGVGYPASKASVIGLTHGLGREIIRKNIR 200 Query: 203 VNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTG 262 V +APG ++ G P + + A P++R+ EIA+ L+LAS LAS +T Sbjct: 201 VVGVAPGVVNTD---MTNGNPPEIMEGYLKALPMKRMLEPEEIANVYLFLASDLASGITA 257 Query: 263 AVLVADG 269 + DG Sbjct: 258 TTVSVDG 264 >1GEE-A nrPDB Length = 261 Score = 114 bits (285), Expect = 5e-26, Method: Compositional matrix adjust. Identities = 76/249 (30%), Positives = 119/249 (47%), Gaps = 2/249 (0%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L KV ITG +G+G +A F V+ RS + + G + + Sbjct: 5 LEGKVVVITGSSTGLGKSMAIRFATEKAKVVVNYRSKEDEANSVLEEIKKVGGEAIAVKG 64 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 DV V+ V A+KEFG++D++IN A + +S + + V+D + +G F S Sbjct: 65 DVTVESDVINLVQSAIKEFGKLDVMINNAGLENPVSSHEMSLSDWNKVIDTNLTGAFLGS 124 Query: 146 RVLYEKFFR-DHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVN 204 R + F D G ++N+++ L VH ++K + MT LA+E+ P+ IRVN Sbjct: 125 REAIKYFVENDIKGTVINMSSVHEKIPWPLFVHYAASKGGMKLMTETLALEYAPKGIRVN 184 Query: 205 SLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAV 264 ++ PG I+ + P+ + + P+ +G EIA +LAS ASYVTG Sbjct: 185 NIGPGAINTPINAEKFADPEQRADVE-SMIPMGYIGEPEEIAAVAAWLASSEASYVTGIT 243 Query: 265 LVADGGAWL 273 L ADGG L Sbjct: 244 LFADGGMTL 252 >2PNF-A nrPDB Length = 248 Score = 111 bits (278), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 78/252 (30%), Positives = 125/252 (49%), Gaps = 13/252 (5%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L+ KV+ +TG GIG IAE G +I S R A ++A G + + M Sbjct: 5 LQGKVSLVTGSTRGIGRAIAEKLASAGSTVIITGTSGERAKAVAEEIANKYGVKAHGVEM 64 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 ++ + ++ A ++ IDIL+N A +S ++ V+ ++ +GTF V+ Sbjct: 65 NLLSEESINKAFEEIYNLVDGIDILVNNAGITRDKLFLRMSLLDWEEVLKVNLTGTFLVT 124 Query: 146 RVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNS 205 + K + G IVNI++ +G G QV+ + KA + T+ LA E P+N+ VN+ Sbjct: 125 QNSLRKMIKQRWGRIVNISSVVGFTGNVGQVNYSTTKAGLIGFTKSLAKELAPRNVLVNA 184 Query: 206 LAPGPISGTEGLRRLGGPQASLSTKVTAS-----PLQRLGNKTEIAHSVLYLASPLASYV 260 +APG I A LS ++ PL R G+ E+A+ VL+L S LASY+ Sbjct: 185 VAPGFIETD--------MTAVLSEEIKQKYKEQIPLGRFGSPEEVANVVLFLCSELASYI 236 Query: 261 TGAVLVADGGAW 272 TG V+ +GG + Sbjct: 237 TGEVIHVNGGMF 248 >4JRO-A nrPDB Length = 271 Score = 109 bits (273), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 77/248 (31%), Positives = 121/248 (48%), Gaps = 9/248 (3%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L+ KVA +TGG GIG IA + G + P KL G + Sbjct: 27 LQGKVAVVTGGSRGIGRDIAINLAKEGANIFFNYNGSPEAAEETAKLVAEHGVEVEAMKA 86 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAA---GNFLCPAGALSFNAFKTVMDIDTSGTF 142 +V V A QA++ FGR+DIL+N A N L + + + V++I+ GTF Sbjct: 87 NVAIAEDVDAFFKQAIERFGRVDILVNNAGITRDNLLMR---MKEDEWDDVININLKGTF 143 Query: 143 NVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIR 202 ++ + + G I+N+ + +G G A Q + ++KA V +T+ A E P+ I Sbjct: 144 LCTKAVSRTMMKQRAGKIINMASVVGLIGNAGQANYVASKAGVIGLTKTTARELAPRGIN 203 Query: 203 VNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTG 262 VN++APG I+ T+ +L + + + PL G +IA++VL+LAS + Y+TG Sbjct: 204 VNAVAPGFIT-TDMTDKL--DEKTKEAMLAQIPLGAYGTTEDIANAVLFLASDASKYITG 260 Query: 263 AVLVADGG 270 L DGG Sbjct: 261 QTLSVDGG 268 >3RSH-A nrPDB Length = 251 Score = 108 bits (269), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 74/251 (29%), Positives = 126/251 (50%), Gaps = 13/251 (5%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L KVA +TG GIG IAE+ G + + S + A+ ++ G +++ Sbjct: 10 LEGKVALVTGASRGIGKAIAELLAERGAKVIGTATSE----SGAQAISDYLGDNGKGMAL 65 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAA---GNFLCPAGALSFNAFKTVMDIDTSGTF 142 +V P ++ A + EFG +DIL+N A N L + + +M+ + + F Sbjct: 66 NVTNPESIEAVLKAITDEFGGVDILVNNAGITRDNLLMR---MKEEEWSDIMETNLTSIF 122 Query: 143 NVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIR 202 +S+ + + G I+N+ + +G G A Q + +AKA V T+ +A E + + Sbjct: 123 RLSKAVLRGMMKKRQGRIINVGSVVGTMGNAGQANYAAAKAGVIGFTKSMAREVASRGVT 182 Query: 203 VNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTG 262 VN++APG I T+ + L Q + + + P RLG+ EIA +V +LASP A+Y+TG Sbjct: 183 VNTVAPGFIE-TDMTKALNDEQRTAT--LAQVPAGRLGDPREIASAVAFLASPEAAYITG 239 Query: 263 AVLVADGGAWL 273 L +GG ++ Sbjct: 240 ETLHVNGGMYM 250 >5ITV-A nrPDB Length = 255 Score = 107 bits (268), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 77/251 (30%), Positives = 122/251 (48%), Gaps = 10/251 (3%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L DK ITGG SGIG+ + F+ + V+A + RK R + Sbjct: 5 LTDKTVLITGGASGIGYAAVQAFLGQQANVVVADIDEAQGEAMVRK---ENNDRLHFVQT 61 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 D+ A AV+ A+ FG +D+LIN A + P + + + V+ ++ +G F +S Sbjct: 62 DITDEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELSDWNKVLQVNLTGMFLMS 121 Query: 146 RVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSA-KAAVDAMTRHLAVEWGPQNIRVN 204 + + G I+N T ++G + A +A K V +T+ +AV++ IRVN Sbjct: 122 KHALKHMLAAGKGNIIN-TCSVGGLVAWPDIPAYNASKGGVLQLTKSMAVDYAKHQIRVN 180 Query: 205 SLAPG----PISGTEGLRRLGGPQASLS-TKVTASPLQRLGNKTEIAHSVLYLASPLASY 259 + PG P++ L G + K +PL RLG EIA+ +L+LAS L+SY Sbjct: 181 CVCPGIIDTPLNEKSFLENNEGTLEEIKKEKAKVNPLLRLGKPEEIANVMLFLASDLSSY 240 Query: 260 VTGAVLVADGG 270 +TG+ + ADGG Sbjct: 241 MTGSAITADGG 251 >2EW8-A nrPDB Length = 249 Score = 107 bits (267), Expect = 7e-24, Method: Compositional matrix adjust. Identities = 86/247 (34%), Positives = 115/247 (46%), Gaps = 8/247 (3%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRS-LPRVLTAARKLAGATGRRCLPLS 84 L+DK+A ITGG +GIG IAE F G IA P A R L GRR L + Sbjct: 5 LKDKLAVITGGANGIGRAIAERFAVEGADIAIADLVPAPEAEAAIRNL----GRRVLTVK 60 Query: 85 MDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNV 144 DV P V A Q + FGR DIL+N A L P L+F +K +I+ F + Sbjct: 61 CDVSQPGDVEAFGKQVISTFGRCDILVNNAGIYPLIPFDELTFEQWKKTFEINVDSGFLM 120 Query: 145 SRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVN 204 ++ R+ G I+N+T+T H S KAA TR LA + G I VN Sbjct: 121 AKAFVPGMKRNGWGRIINLTSTTYWLKIEAYTHYISTKAANIGFTRALASDLGKDGITVN 180 Query: 205 SLAPGPI-SGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGA 263 ++AP + + T L L + A P RL ++ + +LAS AS++TG Sbjct: 181 AIAPSLVRTATTEASALSAMFDVLPNMLQAIP--RLQVPLDLTGAAAFLASDDASFITGQ 238 Query: 264 VLVADGG 270 L DGG Sbjct: 239 TLAVDGG 245 >1AHH-A nrPDB Length = 255 Score = 105 bits (262), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 81/257 (31%), Positives = 135/257 (52%), Gaps = 14/257 (5%) Query: 20 LFCPDLLR--DKVAFITGGGSGIGFRIAEIFMRHGCHTVIA---SRSLPRVLTAARKLAG 74 +F D LR K A ITG G+GIG IA F G V++ + + V+ ++L G Sbjct: 1 MFNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGG 60 Query: 75 -ATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTV 133 A RC D+ + + A D A+ + G++DIL+N A G P + F+ Sbjct: 61 QAFACRC-----DITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFD-MPMADFRRA 114 Query: 134 MDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLA 193 +++ F++S+++ + ++ GGVI+ IT+ S+KAA + R++A Sbjct: 115 YELNVFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMA 174 Query: 194 VEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLA 253 + G +NIRVN +APG I T+ L+ + P+ + +P++RLG +IA++ L+L Sbjct: 175 FDLGEKNIRVNGIAPGAIL-TDALKSVITPEIE-QKMLQHTPIRRLGQPQDIANAALFLC 232 Query: 254 SPLASYVTGAVLVADGG 270 SP AS+V+G +L GG Sbjct: 233 SPAASWVSGQILTVSGG 249 >5CDY-A nrPDB Length = 244 Score = 102 bits (253), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 78/249 (31%), Positives = 125/249 (50%), Gaps = 15/249 (6%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVR 88 K+A +TG GIG IAE+ + G VI + + + A G G+ L ++V Sbjct: 6 KIALVTGASRGIGRAIAELLVERGA-CVIGTATSEKGAEAISAYLGENGK---GLMLNVV 61 Query: 89 APPAVMAAVDQALKEFGRIDILINCAA---GNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 P ++ + EFG +DIL+N A N L + + ++ ++D + + F +S Sbjct: 62 DPTSIDTVLATIRAEFGEVDILVNNAGITRDNLLMR---MKDDEWQDIIDTNLTSVFRLS 118 Query: 146 RVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNS 205 + + + G I+ I + +G G A QV+ +AKA V ++ LA E + I VN Sbjct: 119 KAVMRAMMKKRFGRIITIGSVVGTMGNAGQVNYAAAKAGVIGFSKSLAREVASRGITVNV 178 Query: 206 LAPGPISGTEGLRRLGGPQ-ASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAV 264 +APG I T+ R L Q A + +V P RLG+ EIA +V +LAS ASY++G Sbjct: 179 VAPGFIE-TDMTRTLTDDQRAGILAQV---PANRLGDAKEIASAVAFLASDEASYISGET 234 Query: 265 LVADGGAWL 273 L +GG ++ Sbjct: 235 LHVNGGMYM 243 >4E6P-A nrPDB Length = 259 Score = 101 bits (252), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 75/258 (29%), Positives = 123/258 (47%), Gaps = 13/258 (5%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L K A ITG GIG AE ++R G IA + R AR+ A G + M Sbjct: 6 LEGKSALITGSARGIGRAFAEAYVREGATVAIADIDIER----ARQAAAEIGPAAYAVQM 61 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGT-FNV 144 DV ++ AA+ ++ G +DIL+N AA L P ++ +++ + I+ +GT F + Sbjct: 62 DVTRQDSIDAAIAATVEHAGGLDILVNNAALFDLAPIVEITRESYEKLFAINVAGTLFTL 121 Query: 145 SRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVN 204 + + GG I+N+ + G RG+AL + KAAV ++T+ ++ I VN Sbjct: 122 QAAARQMIAQGRGGKIINMASQAGRRGEALVAIYCATKAAVISLTQSAGLDLIKHRINVN 181 Query: 205 SLAPGPISGT--EGL-----RRLGGPQASLSTKV-TASPLQRLGNKTEIAHSVLYLASPL 256 ++APG + G +G+ R P+ V A P R+G ++ ++LAS Sbjct: 182 AIAPGVVDGEHWDGVDALFARYENRPRGEKKRLVGEAVPFGRMGTAEDLTGMAIFLASAE 241 Query: 257 ASYVTGAVLVADGGAWLT 274 + Y+ DGG W++ Sbjct: 242 SDYIVSQTYNVDGGNWMS 259 >1K2W-A nrPDB Length = 256 Score = 100 bits (248), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 79/263 (30%), Positives = 121/263 (46%), Gaps = 23/263 (8%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L K A ITG GIG AE ++R G IA +L AAR A G +++ Sbjct: 3 LDGKTALITGSARGIGRAFAEAYVREGARVAIADINLE----AARATAAEIGPAACAIAL 58 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGT-FNV 144 DV ++ V + L +G IDIL+N AA L P ++ ++ + I+ SGT F + Sbjct: 59 DVTDQASIDRCVAELLDRWGSIDILVNNAALFDLAPIVEITRESYDRLFAINVSGTLFMM 118 Query: 145 SRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVN 204 V GG I+N+ + G RG+AL + KAAV ++T+ + I VN Sbjct: 119 QAVARAMIAGGRGGKIINMASQAGRRGEALVGVYCATKAAVISLTQSAGLNLIRHGINVN 178 Query: 205 SLAPGPISGT------------EGLRRLGGPQASLSTKVTAS-PLQRLGNKTEIAHSVLY 251 ++APG + G E L P+ +V A+ P R+G ++ ++ Sbjct: 179 AIAPGVVDGEHWDGVDAKFADYENL-----PRGEKKRQVGAAVPFGRMGRAEDLTGMAIF 233 Query: 252 LASPLASYVTGAVLVADGGAWLT 274 LA+P A Y+ DGG W++ Sbjct: 234 LATPEADYIVAQTYNVDGGNWMS 256 >3WOH-A nrPDB Length = 251 Score = 99.4 bits (246), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 79/253 (31%), Positives = 118/253 (46%), Gaps = 15/253 (5%) Query: 23 PDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVI---ASRSLPRVLTAARKLAGATGR- 78 P L KVA +TGG G+G +A R G I + S + + G T R Sbjct: 6 PGALSGKVALVTGGSRGLGRAMALRLARDGAAVAIVYVSDDSSAKETQGEIERLGGTARS 65 Query: 79 -RCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDID 137 RC DV V V + G +DIL+N A A ++ + VM+ + Sbjct: 66 YRC-----DVSDAEQVTRCVKAVTADLGPVDILVNNAGIIRDGLAASIKDEDYDAVMNTN 120 Query: 138 TSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWG 197 G F + Y F R G I+NI++ G G A Q + SAKA + +T+ +A E Sbjct: 121 LKGAFLFIKACYFGFIRKRSGSIINISSVSGVFGSAGQANYASAKAGLIGLTKSIAKELA 180 Query: 198 PQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLA 257 +N+R N++APG I+ T+ + L S ++ P++R G E+A V +LA + Sbjct: 181 ERNVRCNAVAPGLIA-TDMTQDL----VDDSKRLDPVPMRRFGRPDEVAGLVAFLAGDES 235 Query: 258 SYVTGAVLVADGG 270 SY+TG V+ DGG Sbjct: 236 SYITGQVVCVDGG 248 >6CI9-A nrPDB Length = 259 Score = 98.6 bits (244), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 87/260 (33%), Positives = 124/260 (47%), Gaps = 15/260 (5%) Query: 19 HLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGR 78 H+F L + A +TGG GIG IAE F G VI R+ + L+G G+ Sbjct: 2 HMFTS--LEGRSAIVTGGSKGIGRGIAETFANAGVDVVITGRNQDDLDRTVADLSGTRGK 59 Query: 79 RCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCA-AGNFLCPAGALSF---NAFKTVM 134 + DV P V + + G +DI+ CA AG F P+G L + + V+ Sbjct: 60 -VTAVRADVTDPEDARRTVAETVSRHGGLDIV--CANAGIF--PSGRLEDLTPDDIEQVL 114 Query: 135 DIDTSGT-FNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLA 193 ++ GT + V L HG V+V + T G H G++KAA R A Sbjct: 115 GVNFKGTVYIVQAALQALTASGHGRVVVTSSITGPITGYPGWSHYGASKAAQLGFLRTAA 174 Query: 194 VEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLA 253 +E P+ I +N++ PG I TEGL +G Q L +A P RLG+ +I ++ L+ A Sbjct: 175 MELAPKKITINAVLPGNIM-TEGLDEMG--QDYLDQMASAIPAGRLGSVADIGNAALFFA 231 Query: 254 SPLASYVTGAVLVADGGAWL 273 + A+YVTG LV DGG L Sbjct: 232 TDEAAYVTGQTLVVDGGQVL 251 >4MOW-A nrPDB Length = 256 Score = 98.2 bits (243), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 79/247 (31%), Positives = 120/247 (48%), Gaps = 6/247 (2%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L KVA +TG GIG IA+ G V+ S A G R + + Sbjct: 12 LAGKVAIVTGASKGIGAAIAKALADEGAAVVVNYASSKAGADAVVSAITEAGGRAVAVGG 71 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 DV VD A++ +GR+D+L+N + P A++ ++ D + G + Sbjct: 72 DVSKAADAQRIVDTAIETYGRLDVLVNNSGVYEFAPIEAITEEHYRRQFDTNVFGVLLTT 131 Query: 146 RVLYEKFFRDHGGVIVNITATLGNRG-QALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVN 204 + + G I+NI++ + + A V++G+ K AVDA+T LA+E GP+ IRVN Sbjct: 132 QAAVKHL--GEGASIINISSVVTSITPPASAVYSGT-KGAVDAITGVLALELGPRKIRVN 188 Query: 205 SLAPGPISGTEGLRRLGGPQASLSTKVTA-SPLQRLGNKTEIAHSVLYLASPLASYVTGA 263 ++ PG I TEG G + L +V +PL RLG +IA ++LAS A ++TG Sbjct: 189 AINPGMIV-TEGTHSAGIIGSDLEAQVLGQTPLGRLGEPNDIASVAVFLASDDARWMTGE 247 Query: 264 VLVADGG 270 LV GG Sbjct: 248 HLVVSGG 254 >3OEC-A nrPDB Length = 317 Score = 98.2 bits (243), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 80/270 (29%), Positives = 127/270 (47%), Gaps = 26/270 (9%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIA-----------SRSLPRVLTAARKLAG 74 L+ KVAFITG G G A + G V ++ P L +L Sbjct: 44 LQGKVAFITGAARGQGRTHAVRLAQDGADIVAIDLCRQQPNLDYAQGSPEELKETVRLVE 103 Query: 75 ATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVM 134 GRR + DVR ++ A VD+AL EFG IDIL++ + +L+ + ++ Sbjct: 104 EQGRRIIARQADVRDLASLQAVVDEALAEFGHIDILVSNVGISNQGEVVSLTDQQWSDIL 163 Query: 135 DIDTSGTFNVSR-VLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLA 193 + G ++ R VL R GG ++ +++T+G RG Q H ++K V + LA Sbjct: 164 QTNLIGAWHACRAVLPSMIERGQGGSVIFVSSTVGLRGAPGQSHYAASKHGVQGLMLSLA 223 Query: 194 VEWGPQNIRVNSLAPGPISG----TEGLRRLGGPQ---------ASLSTKVTASPLQRLG 240 E G NIRVNS+ PG ++ E L ++ P A L +++T P+ + Sbjct: 224 NEVGRHNIRVNSVNPGAVNTEMALNEKLLKMFLPHLENPTREDAAELFSQLTLLPIPWV- 282 Query: 241 NKTEIAHSVLYLASPLASYVTGAVLVADGG 270 +++++V +LAS A Y+ GA + DGG Sbjct: 283 EPEDVSNAVAWLASDEARYIHGAAIPVDGG 312 >1Q7C-A nrPDB Length = 244 Score = 97.4 bits (241), Expect = 7e-21, Method: Compositional matrix adjust. Identities = 76/249 (30%), Positives = 122/249 (48%), Gaps = 15/249 (6%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVR 88 K+A +TG GIG IAE G VI + + A GA G+ L ++V Sbjct: 6 KIALVTGASRGIGRAIAETLAARGAK-VIGTATSENGAQAISDYLGANGK---GLMLNVT 61 Query: 89 APPAVMAAVDQALKEFGRIDILINCAA---GNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 P ++ + +++ EFG +DIL+N A N L + + +++ + S F +S Sbjct: 62 DPASIESVLEKIRAEFGEVDILVNNAGITRDNLLMR---MKDEEWNDIIETNLSSVFRLS 118 Query: 146 RVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNS 205 + + + G I+ I + +G G Q + +AKA + ++ LA E + I VN Sbjct: 119 KAVMRAMMKKRHGRIITIGSVVGTMGNGGQANFAAAKAGLIGFSKSLAREVASRGITVNV 178 Query: 206 LAPGPISGTEGLRRLGGPQ-ASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAV 264 +APG I T+ R L Q A + +V P RLG EIA++V +LAS A+Y+TG Sbjct: 179 VAPGFIE-TDMTRALSDDQRAGILAQV---PAGRLGGAQEIANAVAFLASDEAAYITGET 234 Query: 265 LVADGGAWL 273 L +GG ++ Sbjct: 235 LHVNGGMYM 243 >2HQ1-A nrPDB Length = 247 Score = 96.7 bits (239), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 72/245 (29%), Positives = 115/245 (46%), Gaps = 3/245 (1%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L+ K A +TG G+G IA G + V+ L A + A G + Sbjct: 3 LKGKTAIVTGSSRGLGKAIAWKLGNMGANIVLNGSPASTSLDATAEEFKAAGINVVVAKG 62 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 DV+ P V V A+ FGRIDIL+N A +S + V++ + + + Sbjct: 63 DVKNPEDVENMVKTAMDAFGRIDILVNNAGITRDTLMLKMSEKDWDDVLNTNLKSAYLCT 122 Query: 146 RVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNS 205 + + + + G I+NIT+ G G A Q + ++KA + T+ +A E+ + I N+ Sbjct: 123 KAVSKIMLKQKSGKIINITSIAGIIGNAGQANYAASKAGLIGFTKSIAKEFAAKGIYCNA 182 Query: 206 LAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVL 265 +APG I T+ L P + PL+R G E+A+ V +LAS ++Y+TG V+ Sbjct: 183 VAPGIIK-TDMTDVL--PDKVKEMYLNNIPLKRFGTPEEVANVVGFLASDDSNYITGQVI 239 Query: 266 VADGG 270 DGG Sbjct: 240 NIDGG 244 >4Z9Y-A nrPDB Length = 253 Score = 96.7 bits (239), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 75/249 (30%), Positives = 122/249 (48%), Gaps = 6/249 (2%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L+ KVA ITG +G+G +A + GC V + P+ K+ A GRR L L+ Sbjct: 8 LQGKVALITGCDTGLGQGMAIGLAQAGCDIVGVNIVEPK--DTIEKVT-ALGRRFLSLTA 64 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 D+ V++A+ EFG +DIL+N A A S + VM+++ F +S Sbjct: 65 DMSNVSGHAELVEKAVAEFGHVDILVNNAGIIRREDAIEFSEKNWDDVMNLNIKSVFFMS 124 Query: 146 RVLYEKFFRD-HGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVN 204 + + +F + GG I+NI + L +G ++K+AV +TR +A EW I VN Sbjct: 125 QTVARQFIKQGKGGKIINIASMLSFQGGIRVPSYTASKSAVMGVTRLMANEWAKHGINVN 184 Query: 205 SLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAV 264 ++APG ++ T ++L + + P R G ++ ++LAS + Y+ G Sbjct: 185 AIAPGYMA-TNNTQQLRADEERSKEILDRIPAGRWGLPQDLMGPSVFLASSASDYINGYT 243 Query: 265 LVADGGAWL 273 + DGG WL Sbjct: 244 IAVDGG-WL 251 >4M8S-A nrPDB Length = 248 Score = 96.3 bits (238), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 76/250 (30%), Positives = 118/250 (47%), Gaps = 16/250 (6%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLA--GATGRRCLPL 83 L K+A +TG GIG IA+ G + + S + +LA G GR Sbjct: 6 LSGKIALVTGASRGIGAAIADTLAAAGAKVIGTATSESGAAAISERLAQWGGEGR----- 60 Query: 84 SMDVRAPPAVMAAVDQALKEFGRIDILINCAA---GNFLCPAGALSFNAFKTVMDIDTSG 140 ++ P V + K FG++DIL+N A N L + + +M ++ Sbjct: 61 VLNSAEPETVENLIADIEKTFGKLDILVNNAGITRDNLLMR---MKEEEWDDIMQVNLKS 117 Query: 141 TFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQN 200 F S+ + + G I+NIT+ +G G A Q + +AKA + ++ +A E G + Sbjct: 118 VFRASKAVLRGMMKQRAGRIINITSVVGVMGNAGQTNYAAAKAGLIGFSKSMAREVGSRG 177 Query: 201 IRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYV 260 I VN +APG I T+ R L P+ + T + L R G+ +IA +VL+LAS A Y+ Sbjct: 178 ITVNCVAPGFID-TDMTRAL--PEETRQTFTAQTALGRFGDAQDIADAVLFLASDQAKYI 234 Query: 261 TGAVLVADGG 270 TG L +GG Sbjct: 235 TGQTLHVNGG 244 >2C07-A nrPDB Length = 285 Score = 95.9 bits (237), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 65/252 (25%), Positives = 123/252 (48%), Gaps = 7/252 (2%) Query: 19 HLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGR 78 + +C + +KVA +TG G GIG IA++ + H + SR+ + ++ + G Sbjct: 38 YYYCGE---NKVALVTGAGRGIGREIAKMLAKSVSHVICISRTQKSCDSVVDEIK-SFGY 93 Query: 79 RCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDT 138 + DV + +++ L E +DIL+N A + + ++ V+ + Sbjct: 94 ESSGYAGDVSKKEEISEVINKILTEHKNVDILVNNAGITRDNLFLRMKNDEWEDVLRTNL 153 Query: 139 SGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGP 198 + F +++ + ++ + G I+NI++ +G G Q + S+KA V T+ LA E Sbjct: 154 NSLFYITQPISKRMINNRYGRIINISSIVGLTGNVGQANYSSSKAGVIGFTKSLAKELAS 213 Query: 199 QNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLAS 258 +NI VN++APG IS + + ++ + + P R+G E+A+ +L+S + Sbjct: 214 RNITVNAIAPGFISSDMTDKISEQIKKNIISNI---PAGRMGTPEEVANLACFLSSDKSG 270 Query: 259 YVTGAVLVADGG 270 Y+ G V V DGG Sbjct: 271 YINGRVFVIDGG 282 >4BO1-A nrPDB Length = 269 Score = 95.9 bits (237), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 81/257 (31%), Positives = 126/257 (49%), Gaps = 10/257 (3%) Query: 21 FCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRC 80 F L+ KVA +TG GIG IA R G + + S A L A G Sbjct: 20 FQSMSLQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLK-ANGVEG 78 Query: 81 LPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAA---GNFLCPAGALSFNAFKTVMDID 137 L +DV + +V A ++ + G+ I++N A N L + + + V++ + Sbjct: 79 AGLVLDVSSDESVAATLEHIQQHLGQPLIVVNNAGITRDNLLVR---MKDDEWFDVVNTN 135 Query: 138 TSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWG 197 + + +S+ + + G I+NI + +G G A Q + +AKA ++ TR LA E G Sbjct: 136 LNSLYRLSKAVLRGMTKARWGRIINIGSVVGAMGNAGQTNYAAAKAGLEGFTRALAREVG 195 Query: 198 PQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLA 257 + I VN++APG I T+ R L P+A + PL RLG EIA V +LAS A Sbjct: 196 SRAITVNAVAPGFID-TDMTREL--PEAQREALLGQIPLGRLGQAEEIAKVVGFLASDGA 252 Query: 258 SYVTGAVLVADGGAWLT 274 +YVTGA + +GG +++ Sbjct: 253 AYVTGATVPVNGGMYMS 269 >2HSD-A nrPDB Length = 253 Score = 95.5 bits (236), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 87/258 (33%), Positives = 121/258 (46%), Gaps = 22/258 (8%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L K ITGG G+G A + G V+A AR+L A + L Sbjct: 3 LSGKTVIITGGARGLGAEAARQAVAAGARVVLADVLDEEGAATARELGDAARYQHL---- 58 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAA---GNFLCPAGALSFNAFKTVMDIDTSGTF 142 DV V A +EFG +D L+N A G FL S F+ V++I+ +G F Sbjct: 59 DVTIEEDWQRVVAYAREEFGSVDGLVNNAGISTGMFLETE---SVERFRKVVEINLTGVF 115 Query: 143 NVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIR 202 + + GG IVNI++ G G AL G++K V +++ AVE G IR Sbjct: 116 IGMKTVIPAMKDAGGGSIVNISSAAGLMGLALTSSYGASKWGVRGLSKLAAVELGTDRIR 175 Query: 203 VNSLAPG----PISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLAS 258 VNS+ PG P++ G+R+ G + +P+ R+G EIA +V+ L S +S Sbjct: 176 VNSVHPGMTYTPMTAETGIRQGEGNYPN-------TPMGRVGEPGEIAGAVVKLLSDTSS 228 Query: 259 YVTGAVLVADGGAWLTFP 276 YVTGA L DGG W T P Sbjct: 229 YVTGAELAVDGG-WTTGP 245 >4NBV-A nrPDB Length = 246 Score = 95.5 bits (236), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 79/251 (31%), Positives = 118/251 (47%), Gaps = 10/251 (3%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLS- 84 L+ +VA ITG +GIGF A+ F G V+ RV R+ A +S Sbjct: 3 LQGRVAIITGAAAGIGFATAQRFAEDGAIVVLCDVQEARV----REAAARLAATGATVSA 58 Query: 85 --MDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTF 142 +DV V A V L R+DIL+N A ++ F V+D++ G F Sbjct: 59 YRVDVTRRDEVDAMVAAVLAAHQRVDILVNNAGITKDARLAKMTEAQFDAVIDVNLKGVF 118 Query: 143 NVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIR 202 N ++ + GVI+N ++ +G G Q + ++K V T+ A E GP+ +R Sbjct: 119 NCAQAVAGLMTEQGKGVILNASSVVGLYGNFGQTNYAASKFGVIGFTKTWARELGPKGVR 178 Query: 203 VNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTG 262 VN++ PG ++ TE L+ + P L ++ L+RL EIA +LAS ASYV G Sbjct: 179 VNAVCPGFVN-TEILQTV--PDKVLDGMTSSCWLRRLAEPAEIASIYAFLASDDASYVNG 235 Query: 263 AVLVADGGAWL 273 + A GG L Sbjct: 236 VAIEASGGMSL 246 >4NBT-A nrPDB Length = 240 Score = 94.7 bits (234), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 77/253 (30%), Positives = 120/253 (47%), Gaps = 27/253 (10%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLP--- 82 L KVA ITGG G+G IA + G A+ +AG G Sbjct: 4 LEGKVAVITGGAKGLGQAIALAYAEEG----------------AKVIAGDLGDLTYSHPN 47 Query: 83 ---LSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTS 139 + ++V V + ++G+IDIL+N A ++ + V+D++ Sbjct: 48 VEGMYLNVTDVTGVEKFYQSVIDKYGKIDILVNNAGITKDAMTRKMTEAQWDAVIDVNLK 107 Query: 140 GTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQ 199 G FN++R++ + + G I+NI++ +G G Q + + KA V +T A E+ + Sbjct: 108 GVFNLTRLVGPQMQTNGYGSIINISSVVGVFGNIGQANYAATKAGVIGLTMTWAKEFALK 167 Query: 200 --NIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLA 257 N+RVN++APG I T+ L+ + PQ L + L RLG EIA L+LAS A Sbjct: 168 GANVRVNAIAPGYIM-TDILKTV--PQDLLDKFAALTMLNRLGQPEEIAKVALFLASDDA 224 Query: 258 SYVTGAVLVADGG 270 SYVTG + +GG Sbjct: 225 SYVTGQTINVNGG 237 >2UVD-A nrPDB Length = 246 Score = 94.0 bits (232), Expect = 7e-20, Method: Compositional matrix adjust. Identities = 76/253 (30%), Positives = 119/253 (47%), Gaps = 17/253 (6%) Query: 25 LLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIA----SRSLPRVLTAARKLAGATGRRC 80 +L+ KVA +TG GIG IA + G + V+ + V+ +KL G Sbjct: 1 MLKGKVALVTGASRGIGRAIAIDLAKQGANVVVNYAGNEQKANEVVDEIKKL----GSDA 56 Query: 81 LPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAA---GNFLCPAGALSFNAFKTVMDID 137 + + DV V V Q + FG++DIL+N A N L + + TV++ + Sbjct: 57 IAVRADVANAEDVTNMVKQTVDVFGQVDILVNNAGVTKDNLLMR---MKEEEWDTVINTN 113 Query: 138 TSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWG 197 G F ++ + R G IVNI + +G G Q + +AKA V +T+ A E Sbjct: 114 LKGVFLCTKAVSRFMMRQRHGRIVNIASVVGVTGNPGQANYVAAKAGVIGLTKTSAKELA 173 Query: 198 PQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLA 257 +NI VN++APG I+ T+ L + K+ P + G +IA++V + AS + Sbjct: 174 SRNITVNAIAPGFIA-TDMTDVLDENIKAEMLKLI--PAAQFGEAQDIANAVTFFASDQS 230 Query: 258 SYVTGAVLVADGG 270 Y+TG L DGG Sbjct: 231 KYITGQTLNVDGG 243 >2CFC-A nrPDB Length = 250 Score = 93.2 bits (230), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 76/245 (31%), Positives = 112/245 (45%), Gaps = 6/245 (2%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVR 88 +VA +TG SG G IA F+ G S + AR A + L + DV Sbjct: 3 RVAIVTGASSGNGLAIATRFLARGDRVAALDLSAETLEETARTHWHAYADKVLRVRADVA 62 Query: 89 APPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALS---FNAFKTVMDIDTSGTFNVS 145 V AA+ +++FG ID+L+N A AG L F VM ++ G F Sbjct: 63 DEGDVNAAIAATMEQFGAIDVLVNNAGITGNSEAGVLHTTPVEQFDKVMAVNVRGIFLGC 122 Query: 146 RVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNS 205 R + GVIVNI + + ++K AV +T+ +AV++ IR N+ Sbjct: 123 RAVLPHMLLQGAGVIVNIASVASLVAFPGRSAYTTSKGAVLQLTKSVAVDYAGSGIRCNA 182 Query: 206 LAPGPISGTEGLRRLGGPQASLSTKVTAS-PLQRLGNKTEIAHSVLYLASPLASYVTGAV 264 + PG I RL P+ L +V A P + +G ++A +V++LA A+YV GA Sbjct: 183 VCPGMIETPMTQWRLDQPE--LRDQVLARIPQKEIGTAAQVADAVMFLAGEDATYVNGAA 240 Query: 265 LVADG 269 LV DG Sbjct: 241 LVMDG 245 >3U5T-A nrPDB Length = 267 Score = 93.2 bits (230), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 84/258 (32%), Positives = 126/258 (48%), Gaps = 13/258 (5%) Query: 18 RHLFCPDLLR-DKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAG-- 74 +L+ ++ +KVA +TG GIG IA G VI + AA ++AG Sbjct: 16 ENLYFQSMMETNKVAIVTGASRGIGAAIAARLASDGFTVVI---NYAGKAAAAEEVAGKI 72 Query: 75 -ATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTV 133 A G + L DV P AV A + FG +D+L+N A L F V Sbjct: 73 EAAGGKALTAQADVSDPAAVRRLFATAEEAFGGVDVLVNNAGIMPLTTIAETGDAVFDRV 132 Query: 134 MDIDTSGTFNVSRVLYEKFFRDHGGVIVNI-TATLGNRGQALQVHAGSAKAAVDAMTRHL 192 + ++ GTFN R ++ GG I+N+ T+ +G + ++A +AKA V+AMT L Sbjct: 133 IAVNLKGTFNTLREAAQRL--RVGGRIINMSTSQVGLLHPSYGIYA-AAKAGVEAMTHVL 189 Query: 193 AVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYL 252 + E ++I VN++APGP + L G +PL+RLG +IA +V +L Sbjct: 190 SKELRGRDITVNAVAPGPTATDLFLE--GKSDEVRDRFAKLAPLERLGTPQDIAGAVAFL 247 Query: 253 ASPLASYVTGAVLVADGG 270 A P ++V G VL A+GG Sbjct: 248 AGPDGAWVNGQVLRANGG 265 >3OSU-A nrPDB Length = 246 Score = 92.4 bits (228), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 70/250 (28%), Positives = 112/250 (44%), Gaps = 13/250 (5%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVR 88 K A +TG GIG IA G + + A + A G + +V Sbjct: 5 KSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVA 64 Query: 89 APPAVMAAVDQALKEFGRIDILINCAA---GNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 V A + + + +FG +D+L+N A N L + + V+D + G FN Sbjct: 65 DADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMR---MKEQEWDDVIDTNLKGVFNCI 121 Query: 146 RVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNS 205 + + R G I+N+++ +G G Q + + KA V +T+ A E + I VN+ Sbjct: 122 QKATPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGITVNA 181 Query: 206 LAPGPISG--TEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGA 263 +APG I T+ L Q +T PL R G T+IA++V +LAS A Y+TG Sbjct: 182 VAPGFIVSDMTDALSDELKEQM-----LTQIPLARFGQDTDIANTVAFLASDKAKYITGQ 236 Query: 264 VLVADGGAWL 273 + +GG ++ Sbjct: 237 TIHVNGGMYM 246 >4CQM-B nrPDB Length = 244 Score = 92.0 bits (227), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 74/249 (29%), Positives = 114/249 (45%), Gaps = 14/249 (5%) Query: 28 DKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDV 87 DKV + GG GIG +A++ R G + +R+L A+ AG G L S DV Sbjct: 9 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLE----GAKAAAGDLGGDHLAFSCDV 64 Query: 88 RAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRV 147 V ++ K GR++ L+N A N + + + G+ + Sbjct: 65 AKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKA 124 Query: 148 LYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLA 207 + GG IVN+ + +G +G + Q ++K + +R LA E + IRVN +A Sbjct: 125 AMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVA 184 Query: 208 PGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLY-LASPLASYVTGAVLV 266 PG + T+ + L + L + PL R G E+AH+V++ L SP Y+TG VLV Sbjct: 185 PGFVH-TDMTKDL--KEEHLKKNI---PLGRFGETIEVAHAVVFLLESP---YITGHVLV 235 Query: 267 ADGGAWLTF 275 DGG L Sbjct: 236 VDGGLQLIL 244 >2AE2-A nrPDB Length = 260 Score = 91.3 bits (225), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 72/247 (29%), Positives = 114/247 (46%), Gaps = 12/247 (4%) Query: 31 AFITGGGSGIGFRIAEIFMRHGCHTVIASRS---LPRVLTAARKLAGATGRRCLPLSMDV 87 A +TGG GIG+ I E G SR+ L LT R + G + D+ Sbjct: 12 ALVTGGSRGIGYGIVEELASLGASVYTCSRNQKELNDCLTQWR----SKGFKVEASVCDL 67 Query: 88 RAPPAVMAAVDQALKEF-GRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSR 146 + ++ F G+++IL+N A A + + +M I+ +++S Sbjct: 68 SSRSERQELMNTVANHFHGKLNILVNNAGIVIYKEAKDYTVEDYSLIMSINFEAAYHLS- 126 Query: 147 VLYEKFFR-DHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNS 205 VL F + G +V I++ G + G+ K A+D +TR LA EW NIRVN Sbjct: 127 VLAHPFLKASERGNVVFISSVSGALAVPYEAVYGATKGAMDQLTRCLAFEWAKDNIRVNG 186 Query: 206 LAPGPISGTEGLRRLGGPQ--ASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGA 263 + PG I+ + + P+ +L+ + L+R+G E+A V +L P ASYVTG Sbjct: 187 VGPGVIATSLVEMTIQDPEQKENLNKLIDRCALRRMGEPKELAAMVAFLCFPAASYVTGQ 246 Query: 264 VLVADGG 270 ++ DGG Sbjct: 247 IIYVDGG 253 >5VT6-A nrPDB Length = 269 Score = 90.9 bits (224), Expect = 6e-19, Method: Compositional matrix adjust. Identities = 71/247 (28%), Positives = 116/247 (46%), Gaps = 4/247 (1%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVR 88 +VAF+TGG G+G I+ G ++ ++ GR ++DV Sbjct: 26 RVAFVTGGMGGLGAAISRRLHDAGMAVAVSHSERNDHVSTWLMHERDAGRDFKAYAVDVA 85 Query: 89 APPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVL 148 + ++ L +FG++D+LIN A ++ + VM D FNV++ Sbjct: 86 DFESCERCAEKVLADFGKVDVLINNAGITRDATFMKMTKGDWDAVMRTDLDAMFNVTKQF 145 Query: 149 YEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAP 208 G IVNI + G+RG Q + SAKA + T+ LA+E + I VN+++P Sbjct: 146 IAGMVERRFGRIVNIGSVNGSRGAFGQANYASAKAGIHGFTKTLALETAKRGITVNTVSP 205 Query: 209 GPISGTEGLRRLGGPQASLSTKVTAS-PLQRLGNKTEIAHSVLYLASPLASYVTGAVLVA 267 G ++ T + + PQ L K+ P+ RLG E+A + +L S A +VTGA L Sbjct: 206 GYLA-TAMVEAV--PQDVLEAKILPQIPVGRLGRPDEVAALIAFLCSDDAGFVTGADLAI 262 Query: 268 DGGAWLT 274 +GG ++ Sbjct: 263 NGGMHMS 269 >1AE1-A nrPDB Length = 273 Score = 90.9 bits (224), Expect = 6e-19, Method: Compositional matrix adjust. Identities = 69/253 (27%), Positives = 114/253 (45%), Gaps = 13/253 (5%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRS---LPRVLTAAR-KLAGATGRRCL 81 L+ A +TGG GIG+ I E G SR+ L L R K G C Sbjct: 19 LKGTTALVTGGSKGIGYAIVEELAGLGARVYTCSRNEKELDECLEIWREKGLNVEGSVCD 78 Query: 82 PLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGT 141 LS R +M V G+++IL+N A A + + +M + Sbjct: 79 LLSRTER--DKLMQTVAHVFD--GKLNILVNNAGVVIHKEAKDFTEKDYNIIMGTNFEAA 134 Query: 142 FNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNI 201 +++S++ Y G ++ +++ G ++K A++ MT+ LA EW NI Sbjct: 135 YHLSQIAYPLLKASQNGNVIFLSSIAGFSALPSVSLYSASKGAINQMTKSLACEWAKDNI 194 Query: 202 RVNSLAPG----PISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLA 257 RVNS+APG P+ T +++ + + + +P+ R G E++ + +L P A Sbjct: 195 RVNSVAPGVILTPLVET-AIKKNPHQKEEIDNFIVKTPMGRAGKPQEVSALIAFLCFPAA 253 Query: 258 SYVTGAVLVADGG 270 SY+TG ++ ADGG Sbjct: 254 SYITGQIIWADGG 266 >5JS6-A nrPDB Length = 274 Score = 90.9 bits (224), Expect = 6e-19, Method: Compositional matrix adjust. Identities = 69/233 (29%), Positives = 117/233 (50%), Gaps = 13/233 (5%) Query: 48 FMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRI 107 F+ G VI + ++L GA C DV V V + ++ FGR+ Sbjct: 31 FVNSGARVVICDKDESGGRALEQELPGAVFILC-----DVTQEDDVKTLVSETIRRFGRL 85 Query: 108 DILINCAAGNFLCPA--GALSFNAFKTVMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITA 165 D ++N AG+ P S F+ +++++ GT+ +++ L + R G ++NI++ Sbjct: 86 DCVVN-NAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK-LALPYLRKSQGNVINISS 143 Query: 166 TLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISG---TEGLRRLGG 222 +G GQA V + K AV AMT+ LA++ P +RVN ++PG I E + Sbjct: 144 LVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALMPD 203 Query: 223 PQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVADGGAWLTF 275 P+A++ + A PL R+G E+ + ++LAS A++ TG L+ GGA L + Sbjct: 204 PRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCTGIELLVTGGAELGY 255 >5U9P-A nrPDB Length = 265 Score = 90.1 bits (222), Expect = 9e-19, Method: Compositional matrix adjust. Identities = 71/245 (28%), Positives = 103/245 (42%), Gaps = 2/245 (0%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L + A ITG G GIG +A G VI R+ + T AR+ G Sbjct: 18 LDGRRALITGSGRGIGLTLARGLAEAGAAIVINDRNEEKAATLARRFRD-EGFAADHAVF 76 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 DV V AA+D+ G IDIL+N A P A + + +M ++ G FNV+ Sbjct: 77 DVAEHAQVRAAIDEFEARVGAIDILVNNAGIQRRAPLDAFEPDDWHALMRVNLDGVFNVA 136 Query: 146 RVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNS 205 + + G I+NI + + + K AV +T+ + +W I+ N Sbjct: 137 QAVARHMIARGHGKIINICSVQSELARPTIAPYAATKGAVRMLTKGMCADWARYGIQANG 196 Query: 206 LAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVL 265 LAPG TE R L A +P R G E+ + ++LAS + +V G L Sbjct: 197 LAPGYFE-TELNRALVDDAAFSDWLCKRTPAGRWGQVDELCGAAIFLASAASDFVNGQTL 255 Query: 266 VADGG 270 DGG Sbjct: 256 FVDGG 260 >5T5Q-A nrPDB Length = 247 Score = 89.7 bits (221), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 70/248 (28%), Positives = 112/248 (45%), Gaps = 8/248 (3%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 ++ +TG GIG IAE+F G + V+ L R A + + R + Sbjct: 7 FENRTLVLTGANGGIGRAIAELFHASGANLVLTD--LDREGLDAFAASLGSPERIATIKA 64 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 D + V A++ FG ID L+ A P +S + + I+ G F + Sbjct: 65 DASSADDAEKTVALAMERFGGIDFLVPSAGIYQAKPFAEMSDADWHRTISINLDGVFYLC 124 Query: 146 RVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNS 205 + D IV + + RG + H G+ K A+ +MTR L+ E P+ RVN Sbjct: 125 KRALPALKEDSS--IVTLASLAAYRGAYVNAHYGATKGAMVSMTRALSRELAPKT-RVNG 181 Query: 206 LAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVL 265 ++PG I L + + +T +PL+RLG +EIA + +L SP AS+VTG + Sbjct: 182 VSPGIIETPMTSELL---KTRMDETMTQTPLKRLGKPSEIASVIAFLCSPAASFVTGETI 238 Query: 266 VADGGAWL 273 +GG ++ Sbjct: 239 QVNGGIYM 246 >3OIC-A nrPDB Length = 258 Score = 89.4 bits (220), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 67/245 (27%), Positives = 116/245 (47%), Gaps = 3/245 (1%) Query: 27 RDKVAFITGGGSGIGFRIAEIFMRHGCHTVIA-SRSLPRVLTAARKLAGATGRRCLPLSM 85 ++K A +TG G+G A +G + VI +RS L A ++ G + L + Sbjct: 3 QNKCALVTGSSRGVGKAAAIRLAENGYNIVINYARSKKAALETAEEIE-KLGVKVLVVKA 61 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 +V P + Q + FGR+D+ +N AA L P L + M+I+ + Sbjct: 62 NVGQPAKIKEMFQQIDETFGRLDVFVNNAASGVLRPVMELEETHWDWTMNINAKALLFCA 121 Query: 146 RVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNS 205 + + ++ GG IV+I++ R G +KAA++A+TR+LAVE P+ I VN+ Sbjct: 122 QEAAKLMEKNGGGHIVSISSLGSIRYLENYTTVGVSKAALEALTRYLAVELSPKQIIVNA 181 Query: 206 LAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVL 265 ++ G I T+ L+ + L +P R+ ++ +V +L S A + G + Sbjct: 182 VSGGAID-TDALKHFPNREDLLEDARQNTPAGRMVEIKDMVDTVEFLVSSKADMIRGQTI 240 Query: 266 VADGG 270 + DGG Sbjct: 241 IVDGG 245 >3EMK-A nrPDB Length = 246 Score = 89.0 bits (219), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 71/249 (28%), Positives = 119/249 (47%), Gaps = 15/249 (6%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L + A +TG G+G IA G + ++ ++LA G R Sbjct: 5 LTGRKALVTGATGGLGEAIARALHAQGAIVGLHGTREEKL----KELAAELGERIFVFPA 60 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAA----GNFLCPAGALSFNAFKTVMDIDTSGT 141 ++ AV A +A +E G +DIL+N A G F+ +S + V+ ++ + Sbjct: 61 NLSDREAVKALGQKAEEEMGGVDILVNNAGITRDGLFV----RMSDEDWDAVLTVNLTSV 116 Query: 142 FNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNI 201 FN++R L R G I+NIT+ +G G Q + ++KA + ++ LA E +N+ Sbjct: 117 FNLTRELTHPMMRRRNGRIINITSIVGVTGNPGQANYCASKAGLIGFSKSLAQEIASRNV 176 Query: 202 RVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVT 261 VN +APG I + + ++ + P++R+G +IA +V+YLAS A+YVT Sbjct: 177 TVNCIAPGFIESAMTGKLNEKQKDAIMGNI---PMKRMGVGADIAAAVVYLASDEAAYVT 233 Query: 262 GAVLVADGG 270 G L +GG Sbjct: 234 GQTLHVNGG 242 >1GEG-A nrPDB Length = 256 Score = 89.0 bits (219), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 78/255 (30%), Positives = 116/255 (45%), Gaps = 18/255 (7%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVR 88 KVA +TG G GIG IA ++ G IA + A ++ A G + + +DV Sbjct: 3 KVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGH-AVAVKVDVS 61 Query: 89 APPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVL 148 V AAV+QA K G D+++N A P +++ V +I+ G + Sbjct: 62 DRDQVFAAVEQARKTLGGFDVIVNNAGVAPSTPIESITPEIVDKVYNINVKGVIWGIQAA 121 Query: 149 YEKFFRD-HGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLA 207 E F ++ HGG I+N + G+ G S+K AV +T+ A + P I VN Sbjct: 122 VEAFKKEGHGGKIINACSQAGHVGNPELAVYSSSKFAVRGLTQTAARDLAPLGITVNGYC 181 Query: 208 PG------------PISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASP 255 PG +S G + LG A + ++T L RL ++A V YLASP Sbjct: 182 PGIVKTPMWAEIDRQVSEAAG-KPLGYGTAEFAKRIT---LGRLSEPEDVAACVSYLASP 237 Query: 256 LASYVTGAVLVADGG 270 + Y+TG L+ DGG Sbjct: 238 DSDYMTGQSLLIDGG 252 >4IIN-A nrPDB Length = 271 Score = 88.6 bits (218), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 68/250 (27%), Positives = 109/250 (43%), Gaps = 13/250 (5%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVR 88 K ITG GIG IA+ G I RS V A + G + + D Sbjct: 30 KNVLITGASKGIGAEIAKTLASMGLKVWINYRSNAEVADALKNELEEKGYKAAVIKFDAA 89 Query: 89 APPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVL 148 + + A+ ++ G + L+N A A + F V+D + + F R Sbjct: 90 SESDFIEAIQTIVQSDGGLSYLVNNAGVVRDKLAIKMKTEDFHHVIDNNLTSAFIGCREA 149 Query: 149 YEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAP 208 + + G +VN+ + +G RG Q + ++K + AM++ A E +NIR NS+ P Sbjct: 150 LKVMSKSRFGSVVNVASIIGERGNMGQTNYSASKGGMIAMSKSFAYEGALRNIRFNSVTP 209 Query: 209 GPISGTEGLRRLGGPQASLSTKVTAS-----PLQRLGNKTEIAHSVLYLASPLASYVTGA 263 G I A+L ++ A PL RLG+ E+A +V +L S +SY+TG Sbjct: 210 GFIETD--------MNANLKDELKADYVKNIPLNRLGSAKEVAEAVAFLLSDHSSYITGE 261 Query: 264 VLVADGGAWL 273 L +GG ++ Sbjct: 262 TLKVNGGLYM 271 >3UF0-A nrPDB Length = 273 Score = 88.6 bits (218), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 77/261 (29%), Positives = 120/261 (45%), Gaps = 13/261 (4%) Query: 17 YRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLA--G 74 ++ + P L + A +TG GSGIG IA + R G H + R+ V A ++A G Sbjct: 20 FQSMTGPFSLAGRTAVVTGAGSGIGRAIAHGYARAGAHVLAWGRT-DGVKEVADEIADGG 78 Query: 75 ATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVM 134 + + D+ A V + L R+D+L+N A PA +S ++ V+ Sbjct: 79 GSAEAVVADLADLEGA----ANVAEELAATRRVDVLVNNAGIIARAPAEEVSLGRWREVL 134 Query: 135 DIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAV 194 ++ + +SR G IV I + L +G ++K AV +TR LA Sbjct: 135 TVNLDAAWVLSRSFGTAMLAHGSGRIVTIASMLSFQGGRNVAAYAASKHAVVGLTRALAS 194 Query: 195 EWGPQNIRVNSLAPGPI--SGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYL 252 EW + + VN+LAPG + + T LR A ++ ++ P R ++ ++L Sbjct: 195 EWAGRGVGVNALAPGYVVTANTAALRADDERAAEITARI---PAGRWATPEDMVGPAVFL 251 Query: 253 ASPLASYVTGAVLVADGGAWL 273 AS ASYV G VL DGG WL Sbjct: 252 ASDAASYVHGQVLAVDGG-WL 271 >3LYL-A nrPDB Length = 247 Score = 87.8 bits (216), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 74/254 (29%), Positives = 123/254 (48%), Gaps = 16/254 (6%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTV--IASRSLPRVLTAARKLAGATGRRCLPL 83 L +KVA +TG GIGF +A G V S++ + K G R + Sbjct: 3 LNEKVALVTGASRGIGFEVAHALASKGATVVGTATSQASAEKFENSMKEKGFKARGLVLN 62 Query: 84 SMDVRAPPAVMAAVDQALKEFGRIDILINCAA---GNFLCPAGALSFNAFKTVMDIDTSG 140 D+ + A + E IDIL+N A N + +S + +++V++ + S Sbjct: 63 ISDIESIQNFFAEIKA---ENLAIDILVNNAGITRDNLMMR---MSEDEWQSVINTNLSS 116 Query: 141 TFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQN 200 F +S+ + G I++I + +G+ G Q + +AKA V ++ LA E +N Sbjct: 117 IFRMSKECVRGMMKKRWGRIISIGSVVGSAGNPGQTNYCAAKAGVIGFSKSLAYEVASRN 176 Query: 201 IRVNSLAPGPISGTEGLRRLGGPQAS-LSTKVTASPLQRLGNKTEIAHSVLYLASPLASY 259 I VN +APG I+ T+ +L Q S ++TK+ P ++G +IA +V +LAS A Y Sbjct: 177 ITVNVVAPGFIA-TDMTDKLTDEQKSFIATKI---PSGQIGEPKDIAAAVAFLASEEAKY 232 Query: 260 VTGAVLVADGGAWL 273 +TG L +GG ++ Sbjct: 233 ITGQTLHVNGGMYM 246 >4DMM-A nrPDB Length = 269 Score = 87.8 bits (216), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 71/246 (28%), Positives = 113/246 (45%), Gaps = 7/246 (2%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L D++A +TG GIG IA G + S A G + Sbjct: 26 LTDRIALVTGASRGIGRAIALELAAAGAKVAVNYASSAGAADEVVAAIAAAGGEAFAVKA 85 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 DV V A ++ +GR+D+L+N A + + +++V+D++ G F S Sbjct: 86 DVSQESEVEALFAAVIERWGRLDVLVNNAGITRDTLLLRMKRDDWQSVLDLNLGGVFLCS 145 Query: 146 RVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNS 205 R + + G I+NI + +G G Q + +AKA V +T+ +A E + I VN+ Sbjct: 146 RAAAKIMLKQRSGRIINIASVVGEMGNPGQANYSAAKAGVIGLTKTVAKELASRGITVNA 205 Query: 206 LAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLAS-PLASYVTGAV 264 +APG I+ T+ L + + PL R G E+A V +LA+ P A+Y+TG V Sbjct: 206 VAPGFIA-TDMTSELAAEKL-----LEVIPLGRYGEAAEVAGVVRFLAADPAAAYITGQV 259 Query: 265 LVADGG 270 + DGG Sbjct: 260 INIDGG 265 >3EZL-A nrPDB Length = 256 Score = 87.0 bits (214), Expect = 8e-18, Method: Compositional matrix adjust. Identities = 68/248 (27%), Positives = 121/248 (48%), Gaps = 7/248 (2%) Query: 25 LLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASR-SLPRVLTAARKLAGATGRRCLPL 83 ++ ++A++TGG GIG I + + G V + PR + A G Sbjct: 10 VMSQRIAYVTGGMGGIGTSICQRLHKDGFRVVAGCGPNSPRRVKWLEDQK-ALGFDFYAS 68 Query: 84 SMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFN 143 +V + A D+ E G ID+L+N A ++ ++ V+D + + FN Sbjct: 69 EGNVGDWDSTKQAFDKVKAEVGEIDVLVNNAGITRDVVFRKMTREDWQAVIDTNLTSLFN 128 Query: 144 VSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRV 203 V++ + + G I+NI++ G +GQ Q + +AKA + T LA E + + V Sbjct: 129 VTKQVIDGMVERGWGRIINISSVNGQKGQFGQTNYSTAKAGIHGFTMSLAQEVATKGVTV 188 Query: 204 NSLAPGPISGTEGLRRLGGPQASLSTKVTAS-PLQRLGNKTEIAHSVLYLASPLASYVTG 262 N+++PG I GT+ ++ + + + K+ A+ P++RLG+ EI V +LAS + + TG Sbjct: 189 NTVSPGYI-GTDMVKAI---RPDVLEKIVATIPVRRLGSPDEIGSIVAWLASEESGFSTG 244 Query: 263 AVLVADGG 270 A +GG Sbjct: 245 ADFSLNGG 252 >1DOH-A nrPDB Length = 283 Score = 86.7 bits (213), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 73/264 (27%), Positives = 124/264 (46%), Gaps = 23/264 (8%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVI----ASRSLPRVLTAARKLAGATGRRCL 81 L KVA +TG G GIG +A R GC ++ ++ S V+ A +K G Sbjct: 27 LEGKVALVTGAGRGIGREMAMELGRRGCKVIVNYANSTESAEEVVAAIKK----NGSDAA 82 Query: 82 PLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGT 141 + +V ++ ++A+K FG++DI+ + + ++ F V I+T G Sbjct: 83 CVKANVGVVEDIVRMFEEAVKIFGKLDIVCSNSGVVSFGHVKDVTPEEFDRVFTINTRGQ 142 Query: 142 FNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHA--GSAKAAVDAMTRHLAVEWGPQ 199 F V+R Y+ + GG ++ + ++ + +A+ HA +K A++ R +A++ + Sbjct: 143 FFVAREAYKHL--EIGGRLI-LMGSITGQAKAVPKHAVYSGSKGAIETFARCMAIDMADK 199 Query: 200 NIRVNSLAPGPISGT-------EGL---RRLGGPQASLSTKVTASPLQRLGNKTEIAHSV 249 I VN +APG I E + L + V SPL+R+G +IA V Sbjct: 200 KITVNVVAPGGIKTDMYHAVCREYIPNGENLSNEEVDEYAAVQWSPLRRVGLPIDIARVV 259 Query: 250 LYLASPLASYVTGAVLVADGGAWL 273 +LAS +VTG V+ DGGA + Sbjct: 260 CFLASNDGGWVTGKVIGIDGGACM 283 >2NM0-A nrPDB Length = 253 Score = 86.3 bits (212), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 74/239 (30%), Positives = 108/239 (45%), Gaps = 15/239 (6%) Query: 32 FITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAPP 91 +TGG GIG IA F G I RS G L + D+ Sbjct: 25 LVTGGNRGIGLAIARAFADAGDKVAITYRS------------GEPPEGFLAVKCDITDTE 72 Query: 92 AVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVLYEK 151 V A + + G +++LI A +S F +V++ + +GTF V + Sbjct: 73 QVEQAYKEIEETHGPVEVLIANAGVTKDQLLMRMSEEDFTSVVETNLTGTFRVVKRANRA 132 Query: 152 FFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPI 211 R G +V I++ +G G A Q + ++KA + R LA E G +NI N +APG + Sbjct: 133 MLRAKKGRVVLISSVVGLLGSAGQANYAASKAGLVGFARSLARELGSRNITFNVVAPGFV 192 Query: 212 SGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVADGG 270 T+ + L Q + V+ PL R EIA +V +LAS ASY+TGAV+ DGG Sbjct: 193 D-TDMTKVLTDEQR--ANIVSQVPLGRYARPEEIAATVRFLASDDASYITGAVIPVDGG 248 >3O4R-A nrPDB Length = 261 Score = 86.3 bits (212), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 77/252 (30%), Positives = 115/252 (45%), Gaps = 11/252 (4%) Query: 24 DLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAG----ATGRR 79 D L +KVA +T GIGF IA + G H V++SR V A L G TG Sbjct: 11 DPLANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTV 70 Query: 80 CLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGN-FLCPAGALSFNAFKTVMDIDT 138 C + R V A+K G IDIL++ AA N F ++ + +DI+ Sbjct: 71 CHVGKAEDRE-----RLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINV 125 Query: 139 SGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGP 198 +++ + + + GG +V +++ +K A+ +T+ LA+E P Sbjct: 126 KAPALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAP 185 Query: 199 QNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLAS 258 +NIRVN LAPG I T R L + + ++RLG + A V +L S AS Sbjct: 186 RNIRVNCLAPGLIK-TSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSEDAS 244 Query: 259 YVTGAVLVADGG 270 Y+TG +V GG Sbjct: 245 YITGETVVVGGG 256 >4K6F-A nrPDB Length = 255 Score = 86.3 bits (212), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 70/248 (28%), Positives = 123/248 (49%), Gaps = 8/248 (3%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAG--ATGRRCLPL 83 + ++A +TGG G+G ++ I + H V+ + S P A R L A GR Sbjct: 9 MTKRIAVVTGGMGGLGEAVS-IRLNDAGHRVVVTYS-PNNTGADRWLTEMHAAGREFHAY 66 Query: 84 SMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFN 143 +DV + +++ +++ G +DIL+N A L + V+ + FN Sbjct: 67 PVDVADHDSCQQCIEKIVRDVGPVDILVNNAGITRDMTLRKLDKVNWDAVIRTNLDSVFN 126 Query: 144 VSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRV 203 +++ + + G IVNI++ G++G Q + +AKA + T+ LA+E + + V Sbjct: 127 MTKPVCDGMVERGWGRIVNISSVNGSKGSVGQTNYAAAKAGMHGFTKSLALEIARKGVTV 186 Query: 204 NSLAPGPISGTEGLRRLGGPQASLSTKVTAS-PLQRLGNKTEIAHSVLYLASPLASYVTG 262 N+++PG ++ T+ + + PQ L TK+ P RLG E+A V YL S A +VTG Sbjct: 187 NTVSPGYLA-TKMVTAI--PQDILDTKILPQIPAGRLGKPEEVAALVAYLCSEEAGFVTG 243 Query: 263 AVLVADGG 270 + + +GG Sbjct: 244 SNIAINGG 251 >5OJG-A nrPDB Length = 260 Score = 85.1 bits (209), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 72/250 (28%), Positives = 117/250 (46%), Gaps = 13/250 (5%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVR 88 KVA +T GIG IAE + G VI SR+ V A L + ++ + Sbjct: 11 KVAIVTAATKGIGLAIAERLLDEGASVVIGSRNQKNVDEAIEYLKNKGLTKVAGIAGHIA 70 Query: 89 APPAVMAAVDQALKEFGRIDILINC-----AAGNFLCPAGALSFNAFKTVMDIDTSGTFN 143 + VD L++FG+I+IL+N A G+ L +S + + +++ F Sbjct: 71 STDDQKKLVDFTLQKFGKINILVNNHGINPAFGHIL----EVSDQVWDKLFEVNVKAGFQ 126 Query: 144 VSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRV 203 ++++++ ++ GG I+ + + G K + +TR LA+ NIRV Sbjct: 127 MTKLVHPHIAKEGGGAIIFNASYSAYKSPPGIAAYGVTKTTLVGLTRALAMGLAKDNIRV 186 Query: 204 NSLAPGPISGTEGLRRL--GGPQASLS-TKVTASPLQRLGNKTEIAHSVLYLASPLASYV 260 N +APG I T+ + L GG A T + L RLG + A +V YLAS +SY+ Sbjct: 187 NGIAPGVIK-TKMSQVLWDGGEDAEKELTDIQEIALGRLGVPDDCAGTVAYLASDDSSYI 245 Query: 261 TGAVLVADGG 270 TG +++ GG Sbjct: 246 TGEMIIIAGG 255 >3D3W-A nrPDB Length = 244 Score = 84.0 bits (206), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 63/242 (26%), Positives = 108/242 (44%), Gaps = 11/242 (4%) Query: 32 FITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAPP 91 +TG G GIG + G V SR+ + + R+ G P+ +D+ Sbjct: 11 LVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIE-----PVCVDL---- 61 Query: 92 AVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVLYEK 151 A ++AL G +D+L+N AA L P ++ AF +++ VS+++ Sbjct: 62 GDWEATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARG 121 Query: 152 FF-RDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGP 210 R G IVN+++ R S K A+D +T+ +A+E GP IRVN++ P Sbjct: 122 LIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTV 181 Query: 211 ISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVADGG 270 + + G P + T + PL + + +++L+L S + TG+ L +GG Sbjct: 182 VMTSMGQATWSDPHKA-KTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240 Query: 271 AW 272 W Sbjct: 241 FW 242 >2O23-A nrPDB Length = 265 Score = 83.2 bits (204), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 78/254 (30%), Positives = 119/254 (46%), Gaps = 24/254 (9%) Query: 30 VAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRA 89 VA ITGG SG+G AE + G V+ A+KL G C+ DV + Sbjct: 14 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKL----GNNCVFAPADVTS 69 Query: 90 PPAVMAAVDQALKEFGRIDILINCA-----AGNFLCPAGAL-SFNAFKTVMDIDTSGTFN 143 V A+ A +FGR+D+ +NCA + + G + F+ V+D++ GTFN Sbjct: 70 EKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFN 129 Query: 144 VSRVLYEKFFR---DHGG---VIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWG 197 V R++ + + D GG VI+N + GQ Q ++K + MT +A + Sbjct: 130 VIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA 189 Query: 198 PQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPL-QRLGNKTEIAHSV-LYLASP 255 P IRV ++APG + GT L L P+ + + P RLG+ E AH V + +P Sbjct: 190 PIGIRVMTIAPG-LFGTPLLTSL--PEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIENP 246 Query: 256 LASYVTGAVLVADG 269 ++ G V+ DG Sbjct: 247 ---FLNGEVIRLDG 257 >3T7C-A nrPDB Length = 299 Score = 83.2 bits (204), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 77/270 (28%), Positives = 121/270 (44%), Gaps = 25/270 (9%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIAS-----------RSLPRVLTAARKLAGATG 77 KVAFITG G G A R G + S P L + A G Sbjct: 29 KVAFITGAARGQGRSHAITLAREGADIIAIDVCKQLDGVKLPMSTPDDLAETVRQVEALG 88 Query: 78 RRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILI-NCAAGNFLCPAGALSFNAFKTVMDI 136 RR + +DVR A+ AAVD + + GR+DI++ N A + + ++ ++D+ Sbjct: 89 RRIIASQVDVRDFDAMQAAVDDGVTQLGRLDIVLANAALASEGTRLNRMDPKTWRDMIDV 148 Query: 137 DTSGTFNVSRVLYEKFFR-DHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVE 195 + +G + +RV GG IV ++ G RG + ++K + + R +A+E Sbjct: 149 NLNGAWITARVAIPHIMAGKRGGSIVFTSSIGGLRGAENIGNYIASKHGLHGLMRTMALE 208 Query: 196 WGPQNIRVNSLAPG----PISGTEGLRRLGGPQASLST----KVTASPLQRLG----NKT 243 GP+NIRVN + P P+ E R+ P T +V + + L Sbjct: 209 LGPRNIRVNIVCPSSVATPMLLNEPTYRMFRPDLENPTVEDFQVASRQMHVLPIPYVEPA 268 Query: 244 EIAHSVLYLASPLASYVTGAVLVADGGAWL 273 +I++++L+L S A Y+TG L DGGA L Sbjct: 269 DISNAILFLVSDDARYITGVSLPVDGGALL 298 >2CDH-G nrPDB Length = 244 Score = 83.2 bits (204), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 68/243 (27%), Positives = 111/243 (45%), Gaps = 6/243 (2%) Query: 30 VAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRA 89 V +TG GIG IA + GC ++ + K A G + + DV Sbjct: 3 VVVVTGASRGIGKAIALSLGKAGCKVLVNYARSAKAAEEVSKQIEAYGGQAITFGGDVSK 62 Query: 90 PPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVLY 149 V A + A+ +G ID+++N A + + + V+D++ +G F ++ Sbjct: 63 EADVEAMMKTAIDAWGTIDVVVNNAGITRDTLLIRMKKSQWDEVIDLNLTGVFLCTQAAT 122 Query: 150 EKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPG 209 + + G I+NI + +G G Q + +AKA V ++ A E +NI VN + PG Sbjct: 123 KIMMKKRKGRIINIASVVGLIGNIGQANYAAAKAGVIGFSKTAAREGASRNINVNVVCPG 182 Query: 210 PISGTEGLRRLGGPQASLSTKVTAS-PLQRLGNKTEIAHSVLYLA-SPLASYVTGAVLVA 267 I+ ++ +LG + K+ + PL R G +A V +LA SP ASY+TG Sbjct: 183 FIA-SDMTAKLG---EDMEKKILGTIPLGRTGQPENVAGLVEFLALSPAASYITGQAFTI 238 Query: 268 DGG 270 DGG Sbjct: 239 DGG 241 >4KMS-A nrPDB Length = 249 Score = 83.2 bits (204), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 70/245 (28%), Positives = 122/245 (49%), Gaps = 13/245 (5%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATG--RRCLPLSMD 86 ++A +TGG GIG + + +++ TV+A+ AA+++ G +C + Sbjct: 11 EIAIVTGGTRGIG-KATALELKNKGLTVVAN--FFSNYDAAKEMEEKYGIKTKCW----N 63 Query: 87 VRAPPAVMAAVDQALKEFGR-IDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 V AV + +EF + + IL+N A +S + V++++ + FN+S Sbjct: 64 VADFEECRQAVKEIEEEFKKPVSILVNNAGITKDKMLHRMSHQDWNDVINVNLNSCFNMS 123 Query: 146 RVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNS 205 + E+ G IVNI++ GQ Q + +AKA + T+ LA E +NI VN Sbjct: 124 SSVMEQMRNQDYGRIVNISSINAQAGQVGQTNYSAAKAGIIGFTKALARETASKNITVNC 183 Query: 206 LAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVL 265 +APG I+ TE + + P+ L+ + + P +RLG EIA +V +L A ++TG + Sbjct: 184 IAPGYIA-TEMVGAV--PEDVLAKIINSIPKKRLGQPEEIARAVAFLVDENAGFITGETI 240 Query: 266 VADGG 270 +GG Sbjct: 241 SINGG 245 >4RZH-A nrPDB Length = 247 Score = 82.8 bits (203), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 71/251 (28%), Positives = 114/251 (45%), Gaps = 17/251 (6%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAG---ATGRRCLP 82 L +VA +TG GIG A G V+ + + TAA + A G + Sbjct: 4 LTAQVALVTGASRGIGKATALALAATGMKVVV---NYAQSSTAADAVVAEIIANGGEAIA 60 Query: 83 LSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTF 142 + +V V + L +F RID+L+N A + ++ V+D++ +G F Sbjct: 61 VQANVANADEVDQLIKTTLDKFSRIDVLVNNAGITRDTLLLRMKLEDWQAVIDLNLTGVF 120 Query: 143 NVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIR 202 ++ + + + G I+NIT+ G G Q + +AKA V T+ +A E + + Sbjct: 121 LCTKAVSKLMLKQKSGRIINITSVAGMMGNPGQANYSAAKAGVIGFTKTVAKELASRGVT 180 Query: 203 VNSLAPGPISG--TEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLAS-PLASY 259 VN++APG I+ TE L P PL R G E+A ++ +LA+ P A+Y Sbjct: 181 VNAVAPGFIATDMTENLN--AEPILQF------IPLARYGQPEEVAGTIRFLATDPAAAY 232 Query: 260 VTGAVLVADGG 270 +TG DGG Sbjct: 233 ITGQTFNVDGG 243 >1H5Q-A nrPDB Length = 265 Score = 82.0 bits (201), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 66/254 (25%), Positives = 106/254 (41%), Gaps = 17/254 (6%) Query: 28 DKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDV 87 +K +TGG GIG G + + RS + K+ G + DV Sbjct: 14 NKTIIVTGGNRGIGLAFTRAVAAAGANVAVIYRSAADAVEVTEKVGKEFGVKTKAYQCDV 73 Query: 88 RAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRV 147 V + Q + G I LI A + + PA L+ F V D++ G FN R Sbjct: 74 SNTDIVTKTIQQIDADLGPISGLIANAGVSVVKPATELTHEDFAFVYDVNVFGVFNTCRA 133 Query: 148 LYEKFFRDHGGVIVNITATLGNR--------GQALQVHAGSAKAAVDAMTRHLAVEWGPQ 199 + + + + + +T+++ ++ G QV S+KAA + + LA EW Sbjct: 134 VAKLWLQKQQKGSIVVTSSMSSQIINQSSLNGSLTQVFYNSSKAACSNLVKGLAAEWASA 193 Query: 200 NIRVNSLAPGPISGTEGL---RRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPL 256 IRVN+L+PG ++ + +++ QAS PL R E+ + L S Sbjct: 194 GIRVNALSPGYVNTDQTAHMDKKIRDHQAS------NIPLNRFAQPEEMTGQAILLLSDH 247 Query: 257 ASYVTGAVLVADGG 270 A+Y+TG DGG Sbjct: 248 ATYMTGGEYFIDGG 261 >3UN1-A nrPDB Length = 260 Score = 81.6 bits (200), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 70/261 (26%), Positives = 120/261 (45%), Gaps = 30/261 (11%) Query: 18 RHLFCPDLLRD--KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSL-PRVLTAARKLAG 74 +L+ ++R+ KV ITG GIG + + V SRS+ P +AG Sbjct: 16 ENLYFQSMMRNQQKVVVITGASQGIGAGLVRAYRDRNYRVVATSRSIKPSADPDIHTVAG 75 Query: 75 ATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVM 134 D+ P V + ++ FGRID L+N A P ++ + + Sbjct: 76 -----------DISKPETADRIVREGIERFGRIDSLVNNAGVFLAKPFVEMTQEDYDHNL 124 Query: 135 DIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNR-----GQALQVHAGSAKAAVDAMT 189 ++ +G F++++ + + G IV+IT +L ++ AL A K ++A+T Sbjct: 125 GVNVAGFFHITQRAAAEMLKQGSGHIVSITTSLVDQPMVGMPSAL---ASLTKGGLNAVT 181 Query: 190 RHLAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSV 249 R LA+E+ +RVN+++PG I + P + ST P+ R+G ++ +V Sbjct: 182 RSLAMEFSRSGVRVNAVSPGVI------KTPMHPAETHSTLAGLHPVGRMGEIRDVVDAV 235 Query: 250 LYLASPLASYVTGAVLVADGG 270 LYL A ++TG +L DGG Sbjct: 236 LYLEH--AGFITGEILHVDGG 254 >2B4Q-A nrPDB Length = 276 Score = 81.6 bits (200), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 72/263 (27%), Positives = 119/263 (45%), Gaps = 10/263 (3%) Query: 14 LPAYRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLA 73 +P H+ L ++A +TGG GIG IA+ + G I +R A +L+ Sbjct: 15 VPRGSHMHPYFSLAGRIALVTGGSRGIGQMIAQGLLEAGARVFICARDAEACADTATRLS 74 Query: 74 GATGRRCLPLSMDVRAPPAVMAAVDQALKEF-GRIDILINCAAGNFLCPAGALSFNAFKT 132 + +P + A +A QAL E R+DIL+N A ++ + + ++ Sbjct: 75 AYGDCQAIPADLSSEAGARRLA---QALGELSARLDILVNNAGTSWGAALESYPVSGWEK 131 Query: 133 VMDIDTSGTFNVSRVLYEKFFR----DHGGVIVNITATLGNRGQALQVHA-GSAKAAVDA 187 VM ++ + F+ + L R ++ ++NI + G Q +A G +KAA+ Sbjct: 132 VMQLNVTSVFSCIQQLLPLLRRSASAENPARVINIGSVAGISAMGEQAYAYGPSKAALHQ 191 Query: 188 MTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAH 247 ++R LA E ++I VN +APG PQA L + P+ R G E+A Sbjct: 192 LSRMLAKELVGEHINVNVIAPGRFPSRMTRHIANDPQA-LEADSASIPMGRWGRPEEMAA 250 Query: 248 SVLYLASPLASYVTGAVLVADGG 270 + LA +Y+TG V+ DGG Sbjct: 251 LAISLAGTAGAYMTGNVIPIDGG 273 >3VZS-A nrPDB Length = 257 Score = 80.9 bits (198), Expect = 6e-16, Method: Compositional matrix adjust. Identities = 68/243 (27%), Positives = 115/243 (47%), Gaps = 5/243 (2%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASR-SLPRVLTAARKLAGATGRRCLPLSMDV 87 ++A++TGG GIG I + + G V + PR + A G + +V Sbjct: 15 RIAYVTGGMGGIGTAICQRLAKDGFRVVAGCGPNSPRREKWLEQQK-ALGFDFIASEGNV 73 Query: 88 RAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRV 147 + A D+ E G +D+LIN A ++ + V+D + + FNV++ Sbjct: 74 ADWDSTKTAFDKVKSEVGEVDVLINNAGITRDVVFRKMTRADWDAVIDTNLTSLFNVTKQ 133 Query: 148 LYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLA 207 + + G IVNI++ G +GQ Q + +AKA + T LA E + + VN+++ Sbjct: 134 VIDGMADRGWGRIVNISSVNGQKGQFGQTNYSTAKAGLHGFTMALAQEVATKGVTVNTVS 193 Query: 208 PGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVA 267 PG I+ T+ ++ + Q L V P++RLG EIA +L+S + + TGA Sbjct: 194 PGYIA-TDMVKAI--RQDVLDKIVATIPVKRLGLPEEIASICAWLSSEESGFSTGADFSL 250 Query: 268 DGG 270 +GG Sbjct: 251 NGG 253 >4HP8-A nrPDB Length = 247 Score = 80.5 bits (197), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 76/256 (29%), Positives = 120/256 (46%), Gaps = 19/256 (7%) Query: 23 PDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLP 82 P L + A +TG +G+G IA G V A+R P + G Sbjct: 4 PFSLEGRKALVTGANTGLGQAIAVGLAAAGAEVVCAARRAP---DETLDIIAKDGGNASA 60 Query: 83 LSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNA--FKTVMDIDTSG 140 L +D P +AA D + + G DIL+N A + A ++ F+ + VMD++ Sbjct: 61 LLIDFADP---LAAKD-SFTDAG-FDILVNNAG--IIRRADSVEFSELDWDEVMDVNLKA 113 Query: 141 TFNVSRVLYEKFF-RDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQ 199 F ++ ++ + G +VNI + L +G +AK V +T+ LA EW + Sbjct: 114 LFFTTQAFAKELLAKGRSGKVVNIASLLSFQGGIRVPSYTAAKHGVAGLTKLLANEWAAK 173 Query: 200 NIRVNSLAPGPI--SGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLA 257 I VN++APG I + TE LR ++ ++ P R G+ +IA + ++L+S A Sbjct: 174 GINVNAIAPGYIETNNTEALRADAARNKAILERI---PAGRWGHSEDIAGAAVFLSSAAA 230 Query: 258 SYVTGAVLVADGGAWL 273 YV GA+L DGG WL Sbjct: 231 DYVHGAILNVDGG-WL 245 >2ZAT-A nrPDB Length = 260 Score = 80.1 bits (196), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 76/256 (29%), Positives = 118/256 (46%), Gaps = 23/256 (8%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAG----ATGRRCL 81 L +KVA +T GIG IA + G H V++SR V L G TG C Sbjct: 12 LENKVALVTASTDGIGLAIARRLAQDGAHVVVSSRKQENVDRTVATLQGEGLSVTGTVCH 71 Query: 82 PLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGN-FLCPAGALSFNAFKTVMDIDTSG 140 + R MA + G +DIL++ AA N F + + ++ ++ Sbjct: 72 VGKAEDRERLVAMA-----VNLHGGVDILVSNAAVNPFFGNIIDATEEVWDKILHVNVKA 126 Query: 141 TFNVSRVLYEKFFRDHGGVIVNITATLG------NRGQALQVHAGSAKAAVDAMTRHLAV 194 T +++ + + + GG ++ I +++G N G +K A+ +T++LAV Sbjct: 127 TVLMTKAVVPEMEKRGGGSVL-IVSSVGAYHPFPNLGPY-----NVSKTALLGLTKNLAV 180 Query: 195 EWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLAS 254 E P+NIRVN LAPG I T + L +A + ++RLGN + A V +L S Sbjct: 181 ELAPRNIRVNCLAPGLIK-TNFSQVLWMDKARKEYMKESLRIRRLGNPEDCAGIVSFLCS 239 Query: 255 PLASYVTGAVLVADGG 270 ASY+TG +V GG Sbjct: 240 EDASYITGETVVVGGG 255 >5EJ2-A nrPDB Length = 308 Score = 79.7 bits (195), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 75/271 (27%), Positives = 120/271 (44%), Gaps = 27/271 (9%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIAS-----------RSLPRVLTAARKLAGATG 77 KVAFI+G G G A + G + S P L L Sbjct: 38 KVAFISGAARGQGRSHAVRLAQEGADIIAIDICGPIENLAYPHSTPEDLAETADLVKDLD 97 Query: 78 RRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILI-NCAAGNFLCPAGALSFNAFKTVMDI 136 RR + +DVR A+ +AVD +++ GR+DI++ N G + N ++ ++DI Sbjct: 98 RRIVTAQVDVRDFEALKSAVDSGVEQLGRLDIIVANAGVGTDGRKLHKIRDNVWQDMIDI 157 Query: 137 DTSGTFNVSRVLYEKFFRD-HGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVE 195 + +G ++ + GG IV ++ G + H +AK V + R AVE Sbjct: 158 NLTGVWHTVKAGVPHVLSGGRGGSIVLTSSVGGRKAYPNTGHYIAAKHGVIGLMRAFAVE 217 Query: 196 WGPQNIRVNSLAPGPISGTEGLR----RLGGPQ---------ASLSTKVTASPLQRLGNK 242 GP IRVN++ P +S T + RL P A +S + P+ + + Sbjct: 218 LGPHMIRVNAVLPTQVSTTMVMNDQTFRLFRPDLENPGPDDFAPISQMMHTLPVPWV-DA 276 Query: 243 TEIAHSVLYLASPLASYVTGAVLVADGGAWL 273 ++I+++VL+LAS + YVTG L D G+ L Sbjct: 277 SDISNAVLFLASDESRYVTGVSLPVDAGSLL 307 >2PH3-A nrPDB Length = 245 Score = 79.3 bits (194), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 59/188 (31%), Positives = 89/188 (47%), Gaps = 3/188 (1%) Query: 83 LSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTF 142 L ++ A A V QA + G +D L+N A + ++ V++ + S F Sbjct: 57 LGANLLEAEAATALVHQAAEVLGGLDTLVNNAGITRDTLLVRMKDEDWEAVLEANLSAVF 116 Query: 143 NVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIR 202 +R + + G IVNIT+ +G G Q + ++KA + TR +A E+ + I Sbjct: 117 RTTREAVKLMMKARFGRIVNITSVVGILGNPGQANYVASKAGLIGFTRAVAKEYAQRGIT 176 Query: 203 VNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTG 262 VN++APG I TE RL PQ + P R G E+A +V +L S A Y+TG Sbjct: 177 VNAVAPGFIE-TEMTERL--PQEVKEAYLKQIPAGRFGRPEEVAEAVAFLVSEKAGYITG 233 Query: 263 AVLVADGG 270 L DGG Sbjct: 234 QTLCVDGG 241 >1NFF-A nrPDB Length = 260 Score = 79.3 bits (194), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 69/247 (27%), Positives = 108/247 (43%), Gaps = 16/247 (6%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLP-LS 84 L KVA ++GG G+G + G V +L K A + Sbjct: 5 LTGKVALVSGGARGMGASHVRAMVAEGAKVVFGD-----ILDEEGKAMAAELADAARYVH 59 Query: 85 MDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNV 144 +DV P AAVD A+ FG + +L+N A + + ++ ++D++ +G F Sbjct: 60 LDVTQPAQWKAAVDTAVTAFGGLHVLVNNAGILNIGTIEDYALTEWQRILDVNLTGVFLG 119 Query: 145 SRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVN 204 R + + G I+NI++ G G + K AV +T+ A+E GP IRVN Sbjct: 120 IRAVVKPMKEAGRGSIINISSIEGLAGTVACHGYTATKFAVRGLTKSTALELGPSGIRVN 179 Query: 205 SLAPGPISGTEGLRRLGGPQAS-LSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGA 263 S+ PG + P + + + L R E+++ V+YLAS +SY TGA Sbjct: 180 SIHPGLVK---------TPMTDWVPEDIFQTALGRAAEPVEVSNLVVYLASDESSYSTGA 230 Query: 264 VLVADGG 270 V DGG Sbjct: 231 EFVVDGG 237 >1E3W-A nrPDB Length = 261 Score = 78.6 bits (192), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 76/254 (29%), Positives = 117/254 (46%), Gaps = 24/254 (9%) Query: 30 VAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRA 89 VA ITGG SG+G A+ + G V+ T A+KL G C+ +V + Sbjct: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGG----NCIFAPANVTS 67 Query: 90 PPAVMAAVDQALKEFGRIDILINCAAGNFLCPA------GALSFNAFKTVMDIDTSGTFN 143 V AA+ A ++FGRID+ +NCA + F+ V++++ GTFN Sbjct: 68 EKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFN 127 Query: 144 VSRVLYEKFFR---DHGG---VIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWG 197 V R++ + D GG VI+N + GQ Q ++K + MT +A + Sbjct: 128 VIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLA 187 Query: 198 PQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPL-QRLGNKTEIAHSV-LYLASP 255 P IRV ++APG + T L L P + + P RLG+ E AH V + + +P Sbjct: 188 PIGIRVVTIAPG-LFATPLLTTL--PDTVRNFLASQVPFPSRLGDPAEYAHLVQMVIENP 244 Query: 256 LASYVTGAVLVADG 269 ++ G V+ DG Sbjct: 245 ---FLNGEVIRLDG 255 >3GRP-A nrPDB Length = 266 Score = 78.6 bits (192), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 69/249 (27%), Positives = 115/249 (46%), Gaps = 15/249 (6%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L + A +TG GIG IA F G + ++ +++A G+ S Sbjct: 25 LTGRKALVTGATGGIGEAIARCFHAQGAIVGLHGTREDKL----KEIAADLGKDVFVFSA 80 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAA----GNFLCPAGALSFNAFKTVMDIDTSGT 141 ++ ++ + A +E IDIL+N A G F+ + + V+ ++ + Sbjct: 81 NLSDRKSIKQLAEVAEREMEGIDILVNNAGITRDGLFV----RMQDQDWDDVLAVNLTAA 136 Query: 142 FNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNI 201 ++R L R G I+NIT+ +G G Q + +AKA + ++ LA E +NI Sbjct: 137 STLTRELIHSMMRRRYGRIINITSIVGVVGNPGQTNYCAAKAGLIGFSKALAQEIASRNI 196 Query: 202 RVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVT 261 VN +APG I + +L Q + P++R+G EIA + +YLAS A+Y+T Sbjct: 197 TVNCIAPGFIK-SAMTDKLNEKQKEAIMAMI--PMKRMGIGEEIAFATVYLASDEAAYLT 253 Query: 262 GAVLVADGG 270 G L +GG Sbjct: 254 GQTLHINGG 262 >4AVY-A nrPDB Length = 242 Score = 78.2 bits (191), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 73/262 (27%), Positives = 112/262 (42%), Gaps = 37/262 (14%) Query: 20 LFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTV--------IASRSLPRVLTAARK 71 +F D+ + +TGG SGIG IA F G V + + PR+ Sbjct: 3 VFQHDIYAGQQVLVTGGSSGIGAAIAMQFAELGAEVVALGLDADGVHAPRHPRIR----- 57 Query: 72 LAGATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFK 131 R L ++ R + + + R+D+L+N A F+ Sbjct: 58 ------REELDITDSQR--------LQRLFEALPRLDVLVNNA--GISRDREEYDLATFE 101 Query: 132 TVMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRH 191 V+ ++ S S+ L GG I+NI + G A + ++K A+ +TR Sbjct: 102 RVLRLNLSAAMLASQ-LARPLLAQRGGSILNIASMYSTFGSADRPAYSASKGAIVQLTRS 160 Query: 192 LAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTK---VTASPLQRLGNKTEIAHS 248 LA E+ + IRVN++APG I G G +A + + +PL R G E+A + Sbjct: 161 LACEYAAERIRVNAIAPGWIDTPLG----AGLKADVEATRRIMQRTPLARWGEAPEVASA 216 Query: 249 VLYLASPLASYVTGAVLVADGG 270 +L P AS+VTGAVL DGG Sbjct: 217 AAFLCGPGASFVTGAVLAVDGG 238 >4DBZ-A nrPDB Length = 281 Score = 78.2 bits (191), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 80/273 (29%), Positives = 126/273 (46%), Gaps = 26/273 (9%) Query: 14 LPAYRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKL- 72 +P H+ D +VA +TG SGIG IA + G + +R + T ++L Sbjct: 15 VPRGSHMATQD---SEVALVTGATSGIGLEIARRLGKEGLRVFVCARGEEGLRTTLKELR 71 Query: 73 -AG--ATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNA 129 AG A GR C DVR+ P + A V ++ +G +D+L+N A L+ Sbjct: 72 EAGVEADGRTC-----DVRSVPEIEALVAAVVERYGPVDVLVNNAGRPGGGATAELADEL 126 Query: 130 FKTVMDIDTSGTFNVSR-VLYEKFFRDHG-GVIVNITATLGNRGQALQVHAGSAKAAVDA 187 + V++ + +G F V++ VL + G G IVNI +T G +G ++K V Sbjct: 127 WLDVVETNLTGVFRVTKQVLKAGGMLERGTGRIVNIASTGGKQGLVHAAPYSASKHGVVG 186 Query: 188 MTRHLAVEWGPQNIRVNSLAPG----PISGTEGLRRLGGPQASLST-----KVTAS-PLQ 237 T+ L +E I VN++ PG P++ + +R +ST ++TA P+ Sbjct: 187 FTKALGLELARTGITVNAVCPGFVETPMAAS--VREHYSDIWEVSTEEAFDRITARVPIG 244 Query: 238 RLGNKTEIAHSVLYLASPLASYVTGAVLVADGG 270 R +E+A V YL P A+ VT L GG Sbjct: 245 RYVQPSEVAEMVAYLIGPGAAAVTAQALNVCGG 277 >2NWQ-A nrPDB Length = 272 Score = 77.8 bits (190), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 68/224 (30%), Positives = 100/224 (44%), Gaps = 9/224 (4%) Query: 32 FITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAPP 91 FITG SG G A F G V+ R R+ A +L+ T R LPL++DVR Sbjct: 25 FITGATSGFGEACARRFAEAGWSLVLTGRREERLQALAGELSAKT--RVLPLTLDVRDRA 82 Query: 92 AVMAAVDQALKEFGRIDILINCAAGNF-LCPAGALSFNAFKTVMDIDTSGTFNVSRVLYE 150 A+ AAVD +EF + LIN A PA + + + T++D + G +R+L Sbjct: 83 AMSAAVDNLPEEFATLRGLINNAGLALGTDPAQSCDLDDWDTMVDTNIKGLLYSTRLLLP 142 Query: 151 KFF-RDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPG 209 + G IVN+ + G G KA V+ + +L + +RV +L PG Sbjct: 143 RLIAHGAGASIVNLGSVAGKWPYPGSHVYGGTKAFVEQFSLNLRCDLQGTGVRVTNLEPG 202 Query: 210 PISGTEGLRRLGGPQASL-STKVTASPLQRLGNKTEIAHSVLYL 252 L R GG QA T A P+Q +IA ++ ++ Sbjct: 203 LCESEFSLVRFGGDQARYDKTYAGAHPIQ----PEDIAETIFWI 242 >3F9I-A nrPDB Length = 249 Score = 77.0 bits (188), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 69/249 (27%), Positives = 113/249 (45%), Gaps = 13/249 (5%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L K + ITG SGIG IA + + G +I+ + ++ + L L Sbjct: 12 LTGKTSLITGASSGIGSAIARLLHKLGSKVIISGSNEEKLKSLGNALKDNYTIEVCNL-- 69 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAG-NFLCPAGALSFNAFKTVMDIDTSGTFNV 144 A + + +DIL+ C AG A + F V+DI+ F + Sbjct: 70 ------ANKEECSNLISKTSNLDILV-CNAGITSDTLAIRMKDQDFDKVIDINLKANFIL 122 Query: 145 SRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVN 204 +R +K + G I+NI++ +G G Q + ++KA + MT+ L+ E + I VN Sbjct: 123 NREAIKKMIQKRYGRIINISSIVGIAGNPGQANYCASKAGLIGMTKSLSYEVATRGITVN 182 Query: 205 SLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAV 264 ++APG I ++ +L Q V PL G ++A++V +LAS ASY+TG Sbjct: 183 AVAPGFIK-SDMTDKLNEKQR--EAIVQKIPLGTYGIPEDVAYAVAFLASNNASYITGQT 239 Query: 265 LVADGGAWL 273 L +GG + Sbjct: 240 LHVNGGMLM 248 >1CYD-A nrPDB Length = 244 Score = 76.6 bits (187), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 60/241 (24%), Positives = 113/241 (46%), Gaps = 11/241 (4%) Query: 31 AFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAP 90 A +TG G GIG + G V +R+ +++ A++ G P+ +D+ Sbjct: 10 ALVTGAGKGIGRDTVKALHASGAKVVAVTRTNSDLVSLAKECPGIE-----PVCVDL--- 61 Query: 91 PAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVLYE 150 A ++AL G +D+L+N AA + P ++ AF ++ F VS+++ Sbjct: 62 -GDWDATEKALGGIGPVDLLVNNAALVIMQPFLEVTKEAFDRSFSVNLRSVFQVSQMVAR 120 Query: 151 KFF-RDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPG 209 R G IVN+++ + + + S K A+ +T+ +A+E GP IRVNS+ P Sbjct: 121 DMINRGVPGSIVNVSSMVAHVTFPNLITYSSTKGAMTMLTKAMAMELGPHKIRVNSVNPT 180 Query: 210 PISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVADG 269 + G + P+ + K PL++ ++ +S+L+L S ++ +G ++ D Sbjct: 181 VVLTDMGKKVSADPEFARKLK-ERHPLRKFAEVEDVVNSILFLLSDRSASTSGGGILVDA 239 Query: 270 G 270 G Sbjct: 240 G 240 >5IZ4-A nrPDB Length = 271 Score = 76.3 bits (186), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 78/259 (30%), Positives = 114/259 (44%), Gaps = 21/259 (8%) Query: 30 VAFITGGGSGIGFRIAEIFMRHGCHTVI-----ASRSLPRVLTAARKLAGATGRRCLPLS 84 V ITG SGIG A F + G I ++R + A + AGA + L Sbjct: 16 VCVITGSASGIGAATALRFAQAGWSVAIGNFDDSTRDAASTVEALCRDAGA---QTLIFD 72 Query: 85 MDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGAL----SFNAFKTVMDIDTSG 140 DV AVD + RID LINCA + P A F F+ V ++ G Sbjct: 73 ADVGKDADCRHAVDMVASRWQRIDALINCAGTTRVIPHNAFDQIDDFE-FERVYRVNLIG 131 Query: 141 TFNVSR----VLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEW 196 + ++R +L E +VN+++ G G + ++K AV+ +T LA Sbjct: 132 LYQMTRAAVPLLRESASATRSTSVVNVSSLAGLNGTGSSIAYAASKGAVNTLTLSLARNL 191 Query: 197 GPQNIRVNSLAPGPISGTEGLRRLGGP--QASLSTKVTASPLQRLGNKTEIAHSVLYLAS 254 P +IRVN+LAPG + LR L LS ++PL+R+ EIA +L + Sbjct: 192 AP-HIRVNALAPGMVDDGLLLRVLDAAAYDGVLSRMTESAPLKRVSRPAEIAELAWFLTA 250 Query: 255 PLASYVTGAVLVADGGAWL 273 A +TG V+ A+ G L Sbjct: 251 H-APAITGQVIAAENGLLL 268 >5JY1-A nrPDB Length = 274 Score = 75.5 bits (184), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 81/269 (30%), Positives = 124/269 (46%), Gaps = 22/269 (8%) Query: 25 LLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIA--SRSLPR-VLTAARKLAGATGRRCL 81 LL +VA +TG G GIG +A F G +IA + S R V R++ G R L Sbjct: 11 LLEQRVALVTGAGGGIGRGVARSFGNEGAAVIIAEINESTGRQVEQEIREMGG----RSL 66 Query: 82 PLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGAL----SFNAFKTVMDID 137 + DV + ++ AAV A+++FG +DIL+N A F+ L + + + Sbjct: 67 FVKTDVTSKASIEAAVRSAVEQFGSLDILVNNA---FVPTPNVLLEEKTDEMLEQTLTTS 123 Query: 138 TSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWG 197 T+ R + G IVN + G L +AKA + +TR A EWG Sbjct: 124 LWATWWAMRAAFVPMRERRWGRIVNFYSIDTETGAWLHGDYNTAKAGIVGLTRSAASEWG 183 Query: 198 PQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTAS-PLQRLGN-KTEIAHSVLYLASP 255 NI VN++AP + T L + + A+ PL R G+ + +I + ++ AS Sbjct: 184 RFNITVNAIAPTAMGAT--FFELAAKNPEFAERSAAARPLGRSGDPEQDIGPAAVFFASE 241 Query: 256 LASYVTGAVLVADGGAWL----TFPNGVK 280 ++ +VTG L DGG L + P G+K Sbjct: 242 MSRFVTGETLHVDGGLHLPGYNSRPAGIK 270 >2FWM-X nrPDB Length = 250 Score = 74.3 bits (181), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 63/256 (24%), Positives = 111/256 (43%), Gaps = 26/256 (10%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLS---M 85 K ++TG G GIG+ A F+ G ++ + P + M Sbjct: 8 KNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQ--------------EQYPFATEVM 53 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 DV V + L E R+D L+N A + LS ++ ++ G FN+ Sbjct: 54 DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLF 113 Query: 146 RVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNS 205 + +F R GG IV + + + + G++KAA+ ++ + +E +R N Sbjct: 114 QQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNV 173 Query: 206 LAPGPISGTEGLRRLGGPQASLSTKVT--------ASPLQRLGNKTEIAHSVLYLASPLA 257 ++PG + T+ R L + ++ PL ++ EIA+++L+LAS LA Sbjct: 174 VSPGS-TDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLA 232 Query: 258 SYVTGAVLVADGGAWL 273 S++T +V DGG+ L Sbjct: 233 SHITLQDIVVDGGSTL 248 >3PXX-A nrPDB Length = 287 Score = 73.6 bits (179), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 78/288 (27%), Positives = 119/288 (41%), Gaps = 46/288 (15%) Query: 26 LRDKVAFITGGGSGIG----FRIAE----IFMRHGCHTVIASRSLPRVLTAARKLAGA-- 75 ++DKV +TGG G G ++AE I + CH I + P L +R L A Sbjct: 8 VQDKVVLVTGGARGQGRSHAVKLAEEGADIILFDICHD-IETNEYP--LATSRDLEEAGL 64 Query: 76 ----TGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGA-LSFNAF 130 TGR+ +DVR AV + A+ EFG++D+++ A +CP GA L AF Sbjct: 65 EVEKTGRKAYTAEVDVRDRAAVSRELANAVAEFGKLDVVVANAG---ICPLGAHLPVQAF 121 Query: 131 KTVMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLG-----------NRGQALQVHAG 179 D+D G N + G I+ + G Sbjct: 122 ADAFDVDFVGVINTVHAALP--YLTSGASIITTGSVAGLIAAAQPPGAGGPQGPGGAGYS 179 Query: 180 SAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPIS----GTEGLRRLGGPQASLSTKVTA-- 233 AK VD+ T LA + PQ+IR N + P ++ + + R P ++ A Sbjct: 180 YAKQLVDSYTLQLAAQLAPQSIRANVIHPTNVNTDMLNSAPMYRQFRPDLEAPSRADALL 239 Query: 234 --SPLQRLG----NKTEIAHSVLYLASPLASYVTGAVLVADGGAWLTF 275 +Q + ++I+++V +LAS + YVTG D GA L F Sbjct: 240 AFPAMQAMPTPYVEASDISNAVCFLASDESRYVTGLQFKVDAGAMLKF 287 >5KOI-A nrPDB Length = 293 Score = 73.6 bits (179), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 66/224 (29%), Positives = 107/224 (47%), Gaps = 44/224 (19%) Query: 75 ATGRRCLPLSM----------DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGA 124 A G+R PL+ DV V A ++ K++G +D L++ A Sbjct: 65 ALGKRVKPLAEQVGSDFVLPCDVEDIATVDAVFEEIEKKWGGLDFLVH-----------A 113 Query: 125 LSFNAFKTVM-----DIDTSGTFNVSRVLY-----------EKFFRDHGGVIVNITATLG 168 + F+ KT + D+ T F+ + V+ EK +D G ++ T T G Sbjct: 114 IGFSD-KTELKGRYADVTTRENFSRTMVISAYSFTEVAQRAEKLMKDGGSIL---TLTYG 169 Query: 169 NRGQALQVH--AGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQAS 226 + + + G AKAA++AM R+LA ++GPQ IRVN+++ GP+ G +G +A Sbjct: 170 GSTRTIPNYNVMGVAKAALEAMVRYLAADYGPQGIRVNAISAGPVRTLAGA-GIGDARAI 228 Query: 227 LSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVADGG 270 S + SPL+R + ++ S +YL S L+S VTG + D G Sbjct: 229 FSYQRRNSPLRRTVDIDDVGKSAVYLLSDLSSGVTGEIHFVDSG 272 >3WTC-A nrPDB Length = 262 Score = 73.2 bits (178), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 74/266 (27%), Positives = 118/266 (44%), Gaps = 34/266 (12%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L K+A +TG GIG IA + G ++ + A+++ A GRR + L+ Sbjct: 6 LSGKIAAVTGAAQGIGKAIALRLAKDGADVILLDVKQDTLAETAKEVE-ALGRRAVALTA 64 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSG----- 140 D+ + + A K G +DI++N A +C K ++DI+ + Sbjct: 65 DISNRDQFRSTLADAAKTLGGLDIMVNNAG---ICQ--------VKPILDIEPAEIEKIF 113 Query: 141 TFNVSRVLY-----EKFFRDHG--GVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLA 193 + NV VL+ F++ G G I+N + G+ G L + K AV A+T+ A Sbjct: 114 SINVQGVLWGMQAAATLFKEKGTKGKIINACSIAGHEGYPLLGAYSATKFAVRALTQSAA 173 Query: 194 VEWGPQNIRVNSLAPGPISGTE-------GLRRLGGPQ--ASLSTKVTASPLQRLGNKTE 244 E I VNS PG I GT+ + + G + A+ V L R+ + Sbjct: 174 KELASSGITVNSYCPG-IVGTDMWVTIDKRMAEITGTEIGATYKKYVEGIALGRVETADD 232 Query: 245 IAHSVLYLASPLASYVTGAVLVADGG 270 +A V YL+S A Y+TG ++ DGG Sbjct: 233 VAGFVAYLSSSDADYMTGQSVLIDGG 258 >3WYE-A nrPDB Length = 256 Score = 73.2 bits (178), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 69/252 (27%), Positives = 112/252 (44%), Gaps = 12/252 (4%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVR 88 KVA +TG G GIG IA ++ G IA + A ++ A G + + +DV Sbjct: 3 KVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGH-AVAVKVDVS 61 Query: 89 APPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVL 148 V AAV+QA K G D+++N A + P ++ K + ++ F + Sbjct: 62 DRDQVFAAVEQARKTLGGFDVIVNNAGIAQIKPLLEVTEEDLKQIYSVNVFSVFFGIQAA 121 Query: 149 YEKFFRD-HGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLA 207 E F ++ HGG I+N + +G + + K AV +T+ A + P I VN Sbjct: 122 VEAFKKEGHGGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQTAARDLAPLGITVNGYC 181 Query: 208 PGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNK---------TEIAHSVLYLASPLAS 258 PG I GT ++ + ++ K + + ++A V +LASP + Sbjct: 182 PG-IVGTGMWEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDVAGLVSFLASPDSD 240 Query: 259 YVTGAVLVADGG 270 Y+TG L+ DGG Sbjct: 241 YMTGQSLLIDGG 252 >3UVE-A nrPDB Length = 286 Score = 72.8 bits (177), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 73/274 (26%), Positives = 115/274 (41%), Gaps = 29/274 (10%) Query: 29 KVAFITGGGSGIG----FRIAEIF-----------MRHGCHTVIASRSLPRVLTAARKLA 73 KVAF+TG G G R+A+ +R G S P L L Sbjct: 12 KVAFVTGAARGQGRSHAVRLAQEGADIIAVDICKPIRAGVVDTAIPASTPEDLAETADLV 71 Query: 74 GATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILI-NCAAGNFLCPAGALSFNAFKT 132 RR + +DVR A+ AAVD +++ GR+DI++ N GN S + Sbjct: 72 KGHNRRIVTAEVDVRDYDALKAAVDSGVEQLGRLDIIVANAGIGNGGDTLDKTSEEDWTE 131 Query: 133 VMDIDTSGTFNVSRVLYEKFFR-DHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRH 191 ++DI+ +G + + GG I+ ++ G + H +AK V + R Sbjct: 132 MIDINLAGVWKTVKAGVPHMIAGGRGGSIILTSSVGGLKAYPHTGHYVAAKHGVVGLMRA 191 Query: 192 LAVEWGPQNIRVNSLAP----GPISGTEGLRRLGGPQASLSTKVTASPLQRLGNK----- 242 VE G IRVNS+ P P+ EG ++ P +P+ ++ + Sbjct: 192 FGVELGQHMIRVNSVHPTHVKTPMLHNEGTFKMFRPDLENPGPDDMAPICQMFHTLPIPW 251 Query: 243 ---TEIAHSVLYLASPLASYVTGAVLVADGGAWL 273 +I+++VL+ AS A Y+TG L D G+ L Sbjct: 252 VEPIDISNAVLFFASDEARYITGVTLPIDAGSCL 285 >3V2G-A nrPDB Length = 271 Score = 72.4 bits (176), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 71/257 (27%), Positives = 108/257 (42%), Gaps = 9/257 (3%) Query: 17 YRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGAT 76 ++ + L K AF+TGG GIG IA+ G + + A Sbjct: 20 FQSMMTSISLAGKTAFVTGGSRGIGAAIAKRLALEGAAVALTYVNAAERAQAVVSEIEQA 79 Query: 77 GRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDI 136 G R + + D R A+ A+ + ++ G +DIL+N A P + F VM + Sbjct: 80 GGRAVAIRADNRDAEAIEQAIRETVEALGGLDILVNSAGIWHSAPLEETTVADFDEVMAV 139 Query: 137 DTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNR--GQALQVHAGSAKAAVDAMTRHLAV 194 + F R GG I+ I + L + +++ S KAA+ +T+ LA Sbjct: 140 NFRAPFVAIRSASRHL--GDGGRIITIGSNLAELVPWPGISLYSAS-KAALAGLTKGLAR 196 Query: 195 EWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLAS 254 + GP+ I VN + PG S + G A + A+ G +IA V +LA Sbjct: 197 DLGPRGITVNIVHPG--STDTDMNPADGDHAEAQRERIATG--SYGEPQDIAGLVAWLAG 252 Query: 255 PLASYVTGAVLVADGGA 271 P +VTGA L DGGA Sbjct: 253 PQGKFVTGASLTIDGGA 269 >4CQL-A nrPDB Length = 261 Score = 72.0 bits (175), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 71/261 (27%), Positives = 120/261 (45%), Gaps = 21/261 (8%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAAR-KLAGATGRRCLP-- 82 LR +A +TG GSGIG ++ G +A+ L R +L G G + P Sbjct: 9 LRSALALVTGAGSGIGRAVSVRLAGEG--ATVAACDLDRAAAQETVRLLGGPGSKEGPPR 66 Query: 83 -----LSMDVRAPPAVMAAVDQALKEFGRI-DILINCAA---GNFLCPAGALSFNAFKTV 133 DV A ++Q F R ++++CA FL +S + + V Sbjct: 67 GNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLH---MSEDDWDKV 123 Query: 134 MDIDTSGTFNVSRVLYEKFFRDHG-GVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHL 192 + ++ GTF V++ + + G I+NI++ +G G Q + ++KA V +T+ Sbjct: 124 IAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTA 183 Query: 193 AVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYL 252 A E G IR NS+ PG I+ T +++ PQ + P+ LG+ ++A V +L Sbjct: 184 ARELGRHGIRCNSVLPGFIA-TPMTQKV--PQKVVDKITEMIPMGHLGDPEDVADVVAFL 240 Query: 253 ASPLASYVTGAVLVADGGAWL 273 AS + Y+TG + GG ++ Sbjct: 241 ASEDSGYITGTSVEVTGGLFM 261 >4RZI-B nrPDB Length = 240 Score = 71.2 bits (173), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 73/253 (28%), Positives = 108/253 (42%), Gaps = 31/253 (12%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGR-RCLPLS 84 L DKV +TGG GIG I ++ G A LA G L + Sbjct: 6 LEDKVIVVTGGNRGIGAAIVKLLQEMGAKV------------AFTDLATDGGNTEALGVV 53 Query: 85 MDVRAPPAVMAAVDQALKEFGRIDILINCAA---GNF---LCPAGALSFNAFKTVMDIDT 138 +V ++ AA + + G + ++ A NF L PA + V++++ Sbjct: 54 ANVTDLESMTAAAAEITDKLGPVYGVVANAGITKDNFFPKLTPAD------WDAVLNVNL 107 Query: 139 SGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGP 198 G + E + G IV I++ G RG Q + + KA V M + LA E Sbjct: 108 KGVAYSIKPFIEGMYERKAGSIVAISSISGERGNVGQTNYSATKAGVIGMMKSLAREGAR 167 Query: 199 QNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTAS-PLQRLGNKTEIAHSVLYLASPLA 257 +R N++APG I L + + K+T P +R G EIA +V +L SP+A Sbjct: 168 YGVRANAVAPGFIDTEMTL----AIREDIREKITKEIPFRRFGKPEEIAWAVAFLLSPVA 223 Query: 258 -SYVTGAVLVADG 269 SYVTG VL +G Sbjct: 224 SSYVTGEVLRVNG 236 >4ALL-A nrPDB Length = 277 Score = 70.1 bits (170), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 69/257 (26%), Positives = 113/257 (43%), Gaps = 8/257 (3%) Query: 18 RHLFCPDLLRDKVAFITG--GGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGA 75 RH+ L +K I G I F +A++ + G V R + L Sbjct: 20 RHMLN---LENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQL 76 Query: 76 TGRRCLPLSMDVRAPPAVMAAVDQALKEFGRID-ILINCAAGNFLCPAGALSFNAFKTVM 134 +DV++ V+ +Q K+ G ID + + A N G S + + + Sbjct: 77 NQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFL 136 Query: 135 DIDTSGTFNVSRVLYE-KFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLA 193 +++++ V +E K GG IV T G G AKA+++A ++LA Sbjct: 137 LAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLA 196 Query: 194 VEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLA 253 ++ GP NIRVN+++ GPI T + +GG L +PL+R ++ E+ + YL Sbjct: 197 LDLGPDNIRVNAISAGPIR-TLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLL 255 Query: 254 SPLASYVTGAVLVADGG 270 S L+S VTG + D G Sbjct: 256 SDLSSGVTGENIHVDSG 272 >6NRP-A nrPDB Length = 263 Score = 70.1 bits (170), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 71/243 (29%), Positives = 107/243 (44%), Gaps = 13/243 (5%) Query: 32 FITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAPP 91 +TG GIG IA + G + +RS + A G+ L DV Sbjct: 28 LVTGSSRGIGKAIALQLAKAGFDVTVHARSRQAEAEQVVQEIQALGQNSHYLMFDVNERQ 87 Query: 92 AVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVLYEK 151 V ++Q +++ G ++ A AL+ + V+ G +NV + L Sbjct: 88 TVQQILEQDVEQHGGFYGVVLNAGLTHDGAFPALTDQDWDEVISTSLDGFYNVLKPLIMP 147 Query: 152 FFR-DHGGVIVNITAT---LGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLA 207 GG IV +++ +GNRGQ V+ +AKA + T+ LA+E + I VN +A Sbjct: 148 MIHLRKGGRIVTLSSVSGIMGNRGQ---VNYSAAKAGLIGATKALALELAKRKITVNCVA 204 Query: 208 PGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVA 267 PG I TE + A + PLQR+G E+A V +L S ASYVT V+ Sbjct: 205 PGLIE-TEMVTDEVKEHA-----LKMIPLQRMGQVDEVASVVKFLCSDEASYVTRQVISV 258 Query: 268 DGG 270 +GG Sbjct: 259 NGG 261 >3R3S-A nrPDB Length = 294 Score = 69.7 bits (169), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 71/253 (28%), Positives = 111/253 (43%), Gaps = 11/253 (4%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARK---LAGATGRRCLP 82 L+D+ A +TGG SGIG A + R G I LP A++ L GR+ + Sbjct: 47 LKDRKALVTGGDSGIGRAAAIAYAREGADVAI--NYLPAEEEDAQQVKALIEECGRKAVL 104 Query: 83 LSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPA-GALSFNAFKTVMDIDTSGT 141 L D+ + V +A + G +DIL A P L+ F+ ++ Sbjct: 105 LPGDLSDESFARSLVHKAREALGGLDILALVAGKQTAIPEIKDLTSEQFQQTFAVNVFAL 164 Query: 142 FNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNI 201 F +++ + G I+ ++ + + + KAA+ +R LA + + I Sbjct: 165 FWITQEAIPLLPK--GASIITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVAEKGI 222 Query: 202 RVNSLAPGPISGTEGLRRLGGP-QASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYV 260 RVN +APGPI L+ GG Q + +P++R G E+A +YLAS +SYV Sbjct: 223 RVNIVAPGPI--WTALQISGGQTQDKIPQFGQQTPMKRAGQPAELAPVYVYLASQESSYV 280 Query: 261 TGAVLVADGGAWL 273 T V GG L Sbjct: 281 TAEVHGVCGGEHL 293 >2Q2Q-A nrPDB Length = 255 Score = 69.7 bits (169), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 66/258 (25%), Positives = 108/258 (41%), Gaps = 16/258 (6%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIAS--RSLPRVLTAARKLAGATGRRCLPL 83 L+ K A +TG SGIG IA++ R G + V+ P + AR G + + Sbjct: 2 LKGKTALVTGSTSGIGLGIAQVLARAGANIVLNGFGDPAPALAEIARH-----GVKAVHH 56 Query: 84 SMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFN 143 D+ + A A +EFG +DIL+N A + P ++ ++ ++ S F+ Sbjct: 57 PADLSDVAQIEALFALAEREFGGVDILVNNAGIQHVAPVEQFPLESWDKIIALNLSAVFH 116 Query: 144 VSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRV 203 +R+ + G I+NI + G G + +AK V +T+ + +E N+ Sbjct: 117 GTRLALPGMRARNWGRIINIASVHGLVGSTGKAAYVAAKHGVVGLTKVVGLETATSNVTC 176 Query: 204 NSLAPGPISGTEGLRRL-------GGP-QASLSTKVTASPLQRLGNKTEIAHSVLYLASP 255 N++ PG + +++ G P QA P + VL+L S Sbjct: 177 NAICPGWVLTPLVQKQIDDRAANGGDPLQAQHDLLAEKQPSLAFVTPEHLGELVLFLCSE 236 Query: 256 LASYVTGAVLVADGGAWL 273 S V GA DGG WL Sbjct: 237 AGSQVRGAAWNVDGG-WL 253 >1UZM-A nrPDB Length = 247 Score = 69.7 bits (169), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 68/242 (28%), Positives = 110/242 (45%), Gaps = 21/242 (8%) Query: 32 FITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAPP 91 +TGG GIG IA+ G + R +GA + + +DV Sbjct: 19 LVTGGNRGIGLAIAQRLAADGHKVAVTHRG-----------SGAP-KGLFGVEVDVTDSD 66 Query: 92 AVMAAVDQALKEFGRIDILINCA---AGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVL 148 AV A + G +++L++ A A FL ++ F+ V++ + +G F V++ Sbjct: 67 AVDRAFTAVEEHQGPVEVLVSNAGLSADAFLMR---MTEEKFEKVINANLTGAFRVAQRA 123 Query: 149 YEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAP 208 R+ G ++ I + G G Q + ++KA V M R +A E N+ N +AP Sbjct: 124 SRSMQRNKFGRMIFIGSVSGLWGIGNQANYAASKAGVIGMARSIARELSKANVTANVVAP 183 Query: 209 GPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVAD 268 G I T+ R L + + P +R+G E+A V +LAS ASY++GAV+ D Sbjct: 184 GYID-TDMTRAL--DERIQQGALQFIPAKRVGTPAEVAGVVSFLASEDASYISGAVIPVD 240 Query: 269 GG 270 GG Sbjct: 241 GG 242 >3V2H-A nrPDB Length = 281 Score = 69.3 bits (168), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 62/257 (24%), Positives = 103/257 (40%), Gaps = 11/257 (4%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLP-RVLTAARKLAGATGRRCLPLS 84 + K A ITG SGIG IA + G + V+ P + T ++AG + L Sbjct: 23 MMTKTAVITGSTSGIGLAIARTLAKAGANIVLNGFGAPDEIRTVTDEVAGLSSGTVLHHP 82 Query: 85 MDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNV 144 D+ P + + FG DIL+N A F+ + ++ ++ S +F+ Sbjct: 83 ADMTKPSEIADMMAMVADRFGGADILVNNAGVQFVEKIEDFPVEQWDRIIAVNLSSSFHT 142 Query: 145 SRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVN 204 R + G I+NI + G + +AK + +T+ +A+E + VN Sbjct: 143 IRGAIPPMKKKGWGRIINIASAHGLVASPFKSAYVAAKHGIMGLTKTVALEVAESGVTVN 202 Query: 205 SLAPG---------PISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASP 255 S+ PG I R + Q + P ++ ++A LYLA Sbjct: 203 SICPGYVLTPLVEKQIPDQARTRGITEEQVINEVMLKGQPTKKFITVEQVASLALYLAGD 262 Query: 256 LASYVTGAVLVADGGAW 272 A+ +TG + DGG W Sbjct: 263 DAAQITGTHVSMDGG-W 278 >3U4C-A nrPDB Length = 281 Score = 68.2 bits (165), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 69/263 (26%), Positives = 108/263 (41%), Gaps = 25/263 (9%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARK-LAGATGRRCLPLS 84 + + AF+ G GIG IA VI SR+L + + LA + L+ Sbjct: 21 MSKRTAFVMGASQGIGKAIALKLADQHFSLVINSRNLDNIESVKEDILAKHPEASVIVLA 80 Query: 85 MDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNV 144 D+ + + GR+D+LIN P GA + F D + TF Sbjct: 81 GDMSDQHTRAGIFQKIESQCGRLDVLINN------IPGGAP--DTFDNCNIEDMTATFTQ 132 Query: 145 SRVLYEKFFR--------DHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEW 196 V Y + + G I+NI L A AA+ +++++++ Sbjct: 133 KTVAYIDAIKRASSLMKQNEFGRIINIVGNLWKEPGANMFTNSMMNAALINASKNISIQL 192 Query: 197 GPQNIRVNSLAPGPISG------TEGLRRLGGPQASLSTKVTAS--PLQRLGNKTEIAHS 248 P NI VN L PG I+ E + + + + AS P++R+G+ E A Sbjct: 193 APHNITVNCLNPGFIATDRYHQFVENVMKKNSISKQKAEEQIASGIPMKRVGSAEETAAL 252 Query: 249 VLYLASPLASYVTGAVLVADGGA 271 +LAS ASY+TG + ADGG+ Sbjct: 253 AAFLASEEASYITGQQISADGGS 275 >1X1T-A nrPDB Length = 260 Score = 67.8 bits (164), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 67/261 (25%), Positives = 108/261 (41%), Gaps = 17/261 (6%) Query: 25 LLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARK-LAGATGRRCLPL 83 +L+ KVA +TG SGIG IA G V+ + R LA G + L Sbjct: 1 MLKGKVAVVTGSTSGIGLGIATALAAQGADIVLNGFGDAAEIEKVRAGLAAQHGVKVLYD 60 Query: 84 SMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFN 143 D+ AV VD A+++ GRIDIL+N A + ++ ++ S F+ Sbjct: 61 GADLSKGEAVRGLVDNAVRQMGRIDILVNNAGIQHTALIEDFPTEKWDAILALNLSAVFH 120 Query: 144 VSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRV 203 + + G I+NI + G A + +AK V T+ A+E Q I Sbjct: 121 GTAAALPHMKKQGFGRIINIASAHGLVASANKSAYVAAKHGVVGFTKVTALETAGQGITA 180 Query: 204 NSLAPG------------PISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLY 251 N++ PG ++ G+ + + LS K P + ++ + ++ Sbjct: 181 NAICPGWVRTPLVEKQISALAEKNGVDQETAARELLSEK---QPSLQFVTPEQLGGTAVF 237 Query: 252 LASPLASYVTGAVLVADGGAW 272 LAS A+ +TG + DGG W Sbjct: 238 LASDAAAQITGTTVSVDGG-W 257 >4TRR-A nrPDB Length = 269 Score = 67.8 bits (164), Expect = 6e-12, Method: Compositional matrix adjust. Identities = 68/264 (25%), Positives = 117/264 (44%), Gaps = 24/264 (9%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L K A +TG SGIG IA + G IA + A ++ A G+ + ++M Sbjct: 12 LNGKTAVVTGAASGIGKEIALELAKAGAAVAIADLNQDGANAVADEINKAGGK-AIGVAM 70 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 DV AV +D+ + FG +DIL++ A + P SF +K + I G F + Sbjct: 71 DVTNEEAVNTGIDKVAEAFGSVDILVSNAGIQIVNPIENYSFADWKKMQAIHVDGAFLTT 130 Query: 146 RVLYEKFFR-DHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVN 204 + + ++ D GGV++ + + + L+ +AK + + R LA E N+R + Sbjct: 131 KAALKHMYKDDRGGVVIYMGSVHSHEASPLKSAYVTAKHGLLGLARVLAKEGAKHNVRSH 190 Query: 205 SLAPG----PISGT---EGLRRLGGPQASLSTKVTASPLQRLGNKT--------EIAHSV 249 + PG P+ E + LG + + KV LGN ++A +V Sbjct: 191 VVCPGFVRTPLVDKQIPEQAKELGISEEEVIKKVM------LGNTVDGVFTTVQDVAQTV 244 Query: 250 LYLASPLASYVTGAVLVADGGAWL 273 L+L++ ++ +TG + G W Sbjct: 245 LFLSAFPSAALTGQSFIVSHG-WF 267 >2YW9-A nrPDB Length = 261 Score = 67.4 bits (163), Expect = 8e-12, Method: Compositional matrix adjust. Identities = 71/241 (29%), Positives = 108/241 (44%), Gaps = 21/241 (8%) Query: 40 IGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAPP---AVMAA 96 +GF IA G ++ ++ R+ A KLA A G L DV A+ A Sbjct: 22 LGFAIAAKLKEAGAEVALSYQA-ERLRPEAEKLAEALGG-ALLFRADVTQDEELDALFAG 79 Query: 97 VDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKT-------VMDIDTSGTFNVSRVLY 149 V +A FG +D L++ A P A+ T +++ V+R Sbjct: 80 VKEA---FGGLDYLVHAIA---FAPREAMEGRYIDTRRQDWLLALEVSAYSLVAVARRA- 132 Query: 150 EKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPG 209 E R+ GG IV +T + AKAA++A R+LA E GP+ +RVN+++ G Sbjct: 133 EPLLREGGG-IVTLTYYASEKVVPKYNVMAIAKAALEASVRYLAYELGPKGVRVNAISAG 191 Query: 210 PISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVADG 269 P+ T R + G +PL+R + E+ + L+L SPLAS +TG V+ D Sbjct: 192 PVR-TVAARSIPGFTKMYDRVAQTAPLRRNITQEEVGNLGLFLLSPLASGITGEVVYVDA 250 Query: 270 G 270 G Sbjct: 251 G 251 >4EGF-A nrPDB Length = 266 Score = 66.2 bits (160), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 68/246 (27%), Positives = 106/246 (43%), Gaps = 2/246 (0%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L K A ITG GIG IA F G V++ R + + A R L G +++ Sbjct: 18 LDGKRALITGATKGIGADIARAFAAAGARLVLSGRDVSELDAARRALGEQFGTDVHTVAI 77 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSG-TFNV 144 D+ P A +A + FG +D+L+N A + P F + ++ Sbjct: 78 DLAEPDAPAELARRAAEAFGGLDVLVNNAGISHPQPVVDTDPQLFDATIAVNLRAPALLA 137 Query: 145 SRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVN 204 S V GG I+ + + ++KA + T+ LA E GP IR N Sbjct: 138 SAVGKAMVAAGEGGAIITVASAAALAPLPDHYAYCTSKAGLVMATKVLARELGPHGIRAN 197 Query: 205 SLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAV 264 S+ P + TE +R+ G +A + + PL R E++ +V++LAS AS + G Sbjct: 198 SVCP-TVVLTEMGQRVWGDEAKSAPMIARIPLGRFAVPHEVSDAVVWLASDAASMINGVD 256 Query: 265 LVADGG 270 + DGG Sbjct: 257 IPVDGG 262 >3A28-C nrPDB Length = 258 Score = 65.5 bits (158), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 69/257 (26%), Positives = 115/257 (44%), Gaps = 20/257 (7%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAAR---KLAGATGRRCLPLSM 85 KVA +TGG GIG I+E G +A LP+ A KL A ++ + + + Sbjct: 3 KVAMVTGGAQGIGRGISEKLAADGFDIAVAD--LPQQEEQAAETIKLIEAADQKAVFVGL 60 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 DV +A+D+A ++ G D+L+N A + P ++ K + ++ F Sbjct: 61 DVTDKANFDSAIDEAAEKLGGFDVLVNNAGIAQIKPLLEVTEEDLKQIYSVNVFSVFFGI 120 Query: 146 RVLYEKFFRDHGGV---IVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIR 202 + KF D GV I+N + +G + + K AV +T+ A E P+ Sbjct: 121 QAASRKF--DELGVKGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQAAAQELAPKGHT 178 Query: 203 VNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNK---------TEIAHSVLYLA 253 VN+ APG I GT ++ + ++ K + + ++A V +LA Sbjct: 179 VNAYAPG-IVGTGMWEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDVAGLVSFLA 237 Query: 254 SPLASYVTGAVLVADGG 270 S ++YVTG V++ DGG Sbjct: 238 SENSNYVTGQVMLVDGG 254 >3GDF-A nrPDB Length = 267 Score = 65.5 bits (158), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 72/253 (28%), Positives = 108/253 (42%), Gaps = 15/253 (5%) Query: 26 LRDKVAFITG--GGSGIGFRIAEIFMRHGCHTVIASRSLPR-VLTAARKLAGATGRRCLP 82 L+ KV +TG G G+G A G I S + ++L G + Sbjct: 18 LKGKVVVVTGASGPKGMGIEAARGCAEMGAAVAITYASRAQGAEENVKELEKTYGIKAKA 77 Query: 83 LSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGAL--SFNAFKTVMDIDTSG 140 V + + V + +FG+ID I A +G L S A+ V+ +D +G Sbjct: 78 YKCQVDSYESCEKLVKDVVADFGQIDAFIANAGAT--ADSGILDGSVEAWNHVVQVDLNG 135 Query: 141 TFNVSRVLYEKFFRDHGGVIVNITATLGNRGQAL---QVHAGSAKAAVDAMTRHLAVEWG 197 TF+ ++ + F G +V ITA++ Q AKA M R LA EW Sbjct: 136 TFHCAKAVGHHFKERGTGSLV-ITASMSGHIANFPQEQTSYNVAKAGCIHMARSLANEW- 193 Query: 198 PQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLA 257 RVNS++PG I GL P+ + + P+ R G E+ + +Y AS + Sbjct: 194 RDFARVNSISPGYID--TGLSDFV-PKETQQLWHSMIPMGRDGLAKELKGAYVYFASDAS 250 Query: 258 SYVTGAVLVADGG 270 +Y TGA L+ DGG Sbjct: 251 TYTTGADLLIDGG 263 >5OVL-A nrPDB Length = 300 Score = 65.1 bits (157), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 55/185 (29%), Positives = 89/185 (48%), Gaps = 17/185 (9%) Query: 95 AAVDQALKEF----GRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVLYE 150 AAVD+A KE G +++L+ A + ++ F+ V++ + +G F ++ Sbjct: 119 AAVDRAFKEVEEHQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRCAQRASR 178 Query: 151 KFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGP 210 R G I+ I + G G Q + +AKA + M R ++ E + N +APG Sbjct: 179 TMQRKRFGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTANVVAPGY 238 Query: 211 ISGTEGLRRLGGPQASLSTKVTAS-----PLQRLGNKTEIAHSVLYLASPLASYVTGAVL 265 I TE R +L ++ A P +R+G E+A +V +LAS ASY+ GAV+ Sbjct: 239 ID-TEMTR-------ALDERIQAGALDFIPAKRVGTAEEVAGAVSFLASEDASYIAGAVI 290 Query: 266 VADGG 270 DGG Sbjct: 291 PVDGG 295 >5OVJ-A nrPDB Length = 256 Score = 65.1 bits (157), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 55/185 (29%), Positives = 89/185 (48%), Gaps = 17/185 (9%) Query: 95 AAVDQALKEF----GRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVLYE 150 AAVD+A KE G +++L+ A + ++ F+ V++ + +G F ++ Sbjct: 75 AAVDRAFKEVEEHQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRCAQRASR 134 Query: 151 KFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGP 210 R G I+ I + G G Q + +AKA + M R ++ E + N +APG Sbjct: 135 TMQRKRFGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTANVVAPGY 194 Query: 211 ISGTEGLRRLGGPQASLSTKVTAS-----PLQRLGNKTEIAHSVLYLASPLASYVTGAVL 265 I TE R +L ++ A P +R+G E+A +V +LAS ASY+ GAV+ Sbjct: 195 ID-TEMTR-------ALDERIQAGALDFIPAKRVGTAEEVAGAVSFLASEDASYIAGAVI 246 Query: 266 VADGG 270 DGG Sbjct: 247 PVDGG 251 >3RWB-A nrPDB Length = 247 Score = 65.1 bits (157), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 66/247 (26%), Positives = 112/247 (45%), Gaps = 9/247 (3%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L K A +TG GIG IA G +++ + AA + G++ ++ Sbjct: 4 LAGKTALVTGAAQGIGKAIAARLAADGATVIVSDINAEGAKAAAASI----GKKARAIAA 59 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 D+ P +V A + G IDIL+N A+ + + ++ ++D++ +GTF V+ Sbjct: 60 DISDPGSVKALFAEIQALTGGIDILVNNASIVPFVAWDDVDLDHWRKIIDVNLTGTFIVT 119 Query: 146 RVLYEKFFRDHG--GVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRV 203 R ++ R G G +++I + G +AK V TR LA E G NI Sbjct: 120 RAGTDQ-MRAAGKAGRVISIASNTFFAGTPNMAAYVAAKGGVIGFTRALATELGKYNITA 178 Query: 204 NSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGA 263 N++ PG I ++G++ +A ++ ++ G IA V +LAS A ++TG Sbjct: 179 NAVTPGLIE-SDGVKASPHNEAFGFVEML-QAMKGKGQPEHIADVVSFLASDDARWITGQ 236 Query: 264 VLVADGG 270 L D G Sbjct: 237 TLNVDAG 243 >5B1Y-A nrPDB Length = 270 Score = 65.1 bits (157), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 63/246 (25%), Positives = 110/246 (44%), Gaps = 10/246 (4%) Query: 31 AFITGGGSGIGFRIAEIFMRHGCHTVIASRS----LPRVLTAARKLAGATGRRCLPLSMD 86 A +TGG GIG F R G VIA +S + AR+L + +D Sbjct: 26 ALVTGGSRGIGRATVLRFAREGWSVVIAYKSRADLAEKTAEEARRLGSP---EAYTVRVD 82 Query: 87 VRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSR 146 V P +V + + +++L+N A L S + ++ + ++ +G + V++ Sbjct: 83 VGDPDSVTEMSSRVGELIPHLNVLVNAAGVLQLGGIEETSISEWEETLRVNLTGVYLVTK 142 Query: 147 VLYEKFFRDHGGVIVNITATLGNRGQALQ-VHAGSAKAAVDAMTRHLAVEWGPQNIRVNS 205 +L + IVN+ + G G + V ++KA V +T+ LAV+ IRVN+ Sbjct: 143 LLLPLLRKAKWASIVNVASIAGETGNVVAGVAYSASKAGVIGLTKRLAVQLAGYGIRVNA 202 Query: 206 LAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASY-VTGAV 264 +AP + T+ R + PL+ + ++A ++L+LA P S +TG V Sbjct: 203 VAPSFVE-TDMTRSFLDTPEKRERIASLHPLKIILKPEDVAEAILFLADPRRSRGITGHV 261 Query: 265 LVADGG 270 L + G Sbjct: 262 LSINAG 267 >2AG5-A nrPDB Length = 246 Score = 64.7 bits (156), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 50/185 (27%), Positives = 86/185 (46%), Gaps = 15/185 (8%) Query: 97 VDQALKEFGRIDILINCAA----GNFL-CPAGALSFNAFKTVMDIDTSGTFNVSRVLYEK 151 +DQ E R+D+L N A G L C F+ M+++ + + + K Sbjct: 65 IDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFS-----MNLNVRSMYLMIKAFLPK 119 Query: 152 FFRDHGGVIVNITATLGN-RGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGP 210 G I+N+++ + +G + + KAAV +T+ +A ++ Q IR N + PG Sbjct: 120 MLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGT 179 Query: 211 I---SGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVA 267 + S E ++ G P+ + + + R EIA +YLAS ++YVTG ++ Sbjct: 180 VDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVII 239 Query: 268 DGGAW 272 DGG W Sbjct: 240 DGG-W 243 >1O5I-A nrPDB Length = 249 Score = 64.7 bits (156), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 66/248 (26%), Positives = 110/248 (44%), Gaps = 24/248 (9%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 +RDK + GIG +A++ + G I +R+ +L +G R + Sbjct: 17 IRDKGVLVLAASRGIGRAVADVLSQEGAEVTICARN--------EELLKRSGHRYVVC-- 66 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 D+R +D ++ +DIL+ A G L+ FK +D S N+ Sbjct: 67 DLRKD------LDLLFEKVKEVDILVLNAGGPKAGFFDELTNEDFKEAID---SLFLNMI 117 Query: 146 RVL--YEKFFRDHG-GVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIR 202 +++ Y ++ G G IV IT+ + SA+ A+ + L+ E P I Sbjct: 118 KIVRNYLPAMKEKGWGRIVAITSFSVISPIENLYTSNSARMALTGFLKTLSFEVAPYGIT 177 Query: 203 VNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTG 262 VN +APG + TE ++ L + + + P++R+ EIA V +L S ASY+TG Sbjct: 178 VNCVAPG-WTETERVKELLSEEKKKQVE-SQIPMRRMAKPEEIASVVAFLCSEKASYLTG 235 Query: 263 AVLVADGG 270 +V DGG Sbjct: 236 QTIVVDGG 243 >3GRK-A nrPDB Length = 293 Score = 64.3 bits (155), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 60/193 (31%), Positives = 89/193 (46%), Gaps = 15/193 (7%) Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCA--------AGNFLCPAGALSFNAFKTVMDID 137 DV ++ A + K++G++D L++ G ++ + A F M I Sbjct: 89 DVADAASIDAVFETLEKKWGKLDFLVHAIGFSDKDELTGRYIDTSEA----NFTNTMLIS 144 Query: 138 TSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWG 197 VSR EK D GG I+ +T + G AKAA++A ++LAV+ G Sbjct: 145 VYSLTAVSRRA-EKLMAD-GGSILTLTYYGAEKVMPNYNVMGVAKAALEASVKYLAVDLG 202 Query: 198 PQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLA 257 PQNIRVN+++ GPI T +G + L +PL+R E+ LY S L+ Sbjct: 203 PQNIRVNAISAGPIK-TLAASGIGDFRYILKWNEYNAPLRRTVTIDEVGDVGLYFLSDLS 261 Query: 258 SYVTGAVLVADGG 270 VTG V AD G Sbjct: 262 RSVTGEVHHADSG 274 >3ZV3-A nrPDB Length = 281 Score = 63.9 bits (154), Expect = 8e-11, Method: Compositional matrix adjust. Identities = 71/260 (27%), Positives = 113/260 (43%), Gaps = 23/260 (8%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L +VA ITGG SG+G + + F+ G + +S R+ R+L A G + + Sbjct: 3 LTGEVALITGGASGLGRALVDRFVAEGARVAVLDKSAERL----RELEVAHGGNAVGVVG 58 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILI-NCAAGNFLCPAGALSFN----AFKTVMDIDTSG 140 DVR+ A ++ L FG+ID LI N ++ L + AF + ++ G Sbjct: 59 DVRSLQDQKRAAERCLAAFGKIDTLIPNAGIWDYSTALADLPEDKIDAAFDDIFHVNVKG 118 Query: 141 TFNVSRVLYEKFFRDHGGVIVNITAT--LGNRGQALQVHAGSAKAAVDAMTRHLAVEWGP 198 + + G V+ I+ N G L + K AV + R +A E P Sbjct: 119 YIHAVKACLPALVSSRGSVVFTISNAGFYPNGGGPLYT---ATKHAVVGLVRQMAFELAP 175 Query: 199 QNIRVNSLAPGPI-SGTEGLRRLGGPQASLSTKVTAS------PLQRLGNKTEIAHSVLY 251 +RVN +APG + + G LG + S+S+ A P+ R+ E + ++ Sbjct: 176 H-VRVNGVAPGGMNTDLRGPSSLGLSEQSISSVPLADMLKSVLPIGRMPALEEYTGAYVF 234 Query: 252 LASPLASY-VTGAVLVADGG 270 A+ S TGA+L DGG Sbjct: 235 FATRGDSLPATGALLNYDGG 254 >1HXH-A nrPDB Length = 253 Score = 63.5 bits (153), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 73/256 (28%), Positives = 119/256 (46%), Gaps = 27/256 (10%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L+ KVA +TGG SG+G + ++ + G + + A ++LA G R + + Sbjct: 4 LQGKVALVTGGASGVGLEVVKLLLGEGAKVAFSDIN----EAAGQQLAAELGERSMFVRH 59 Query: 86 DVRAP---PAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALS--FNAFKTVMDIDTSG 140 DV + VMAAV + G +++L+N A L P + F ++ I+T Sbjct: 60 DVSSEADWTLVMAAVQ---RRLGTLNVLVNNAG--ILLPGDMETGRLEDFSRLLKINTES 114 Query: 141 TFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAG--SAKAAVDAMTRHLAVEWGP 198 F + ++ GG I+N+ + + ++ +AG ++KAAV A+TR A+ Sbjct: 115 VF-IGCQQGIAAMKETGGSIINMASV--SSWLPIEQYAGYSASKAAVSALTRAAALSCRK 171 Query: 199 QN--IRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASP-LQRLGNK---TEIAHSVLYL 252 Q IRVNS+ P I + + P+ V P L R G IA VL+L Sbjct: 172 QGYAIRVNSIHPDGIYTP--MMQASLPKGVSKEMVLHDPKLNRAGRAYMPERIAQLVLFL 229 Query: 253 ASPLASYVTGAVLVAD 268 AS +S ++G+ L AD Sbjct: 230 ASDESSVMSGSELHAD 245 >5TF4-A nrPDB Length = 274 Score = 63.5 bits (153), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 56/193 (29%), Positives = 93/193 (48%), Gaps = 15/193 (7%) Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCA--------AGNFLCPAGALSFNAFKTVMDID 137 DV ++ A + K++G++D L++ +G ++ +S + F M+I Sbjct: 70 DVSDSASIDAVFNTIEKKWGKLDFLVHAIGFSDKEELSGRYV----DISESNFMMTMNIS 125 Query: 138 TSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWG 197 +++ EK D GG I+ +T + G AKAA++A ++LAV+ G Sbjct: 126 VYSLTALTKRA-EKLMSD-GGSILTLTYYGAEKVVPNYNVMGVAKAALEASVKYLAVDLG 183 Query: 198 PQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLA 257 P++IRVN+++ GPI T +G + L +PL+R E+ S LYL S L+ Sbjct: 184 PKHIRVNAISAGPIK-TLAASGIGDFRYILKWNEYNAPLRRTVTIEEVGDSALYLLSDLS 242 Query: 258 SYVTGAVLVADGG 270 VTG V D G Sbjct: 243 RSVTGEVHHVDSG 255 >1ENP-A nrPDB Length = 312 Score = 63.5 bits (153), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 54/182 (29%), Positives = 89/182 (48%), Gaps = 7/182 (3%) Query: 93 VMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVLYEKF 152 V A + ++FG IDIL++ A L + + I S VS + + Sbjct: 116 VQEAAECVRQDFGSIDILVHSLANGPEVSKPLLETSRKGYLAAISASSYSFVSLLSHFLP 175 Query: 153 FRDHGGVIVNITATLGNRGQALQVHAG---SAKAAVDAMTRHLAVEWG-PQNIRVNSLAP 208 + GG +++T R + + G SAKAA+++ TR LA E G QNIRVN+++ Sbjct: 176 IMNPGGASISLTYIASER--IIPGYGGGMSSAKAALESDTRVLAFEAGRKQNIRVNTISA 233 Query: 209 GPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVAD 268 GP+ G+ + +G + +P+Q+ E+ ++ +L SPLAS +TGA + D Sbjct: 234 GPL-GSRAAKAIGFIDTMIEYSYNNAPIQKTLTADEVGNAAAFLVSPLASAITGATIYVD 292 Query: 269 GG 270 G Sbjct: 293 NG 294 >3V8B-A nrPDB Length = 283 Score = 63.2 bits (152), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 69/256 (26%), Positives = 107/256 (41%), Gaps = 16/256 (6%) Query: 30 VAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRA 89 VA ITG GSGIG A G R+ V A ++ GA G+ + L DV Sbjct: 30 VALITGAGSGIGRATALALAADGVTVGALGRTRTEVEEVADEIVGAGGQ-AIALEADVSD 88 Query: 90 PPAVMAAVDQALKEFGRIDILI-NCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVL 148 + AV + +FG +DI++ N P L + + ++ GTF + Sbjct: 89 ELQMRNAVRDLVLKFGHLDIVVANAGINGVWAPIDDLKPFEWDETIAVNLRGTFLTLHLT 148 Query: 149 YEKFFRDHGGVIVNITATLGNR-----GQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRV 203 + GG IV +++ G R G +A+ A+ + LA+E G +IRV Sbjct: 149 VPYLKQRGGGAIVVVSSINGTRTFTTPGATAYTATKAAQVAI---VQQLALELGKHHIRV 205 Query: 204 NSLAPGP----ISGTEGLRRLGGPQASLSTKVTASPLQ--RLGNKTEIAHSVLYLASPLA 257 N++ PG IS LR + P+ + G ++A + +L S A Sbjct: 206 NAVCPGAIETNISDNTKLRHEEETAIPVEWPKGQVPITDGQPGRSEDVAELIRFLVSERA 265 Query: 258 SYVTGAVLVADGGAWL 273 +VTG+ + DGG L Sbjct: 266 RHVTGSPVWIDGGQGL 281 >4IIV-A nrPDB Length = 267 Score = 62.8 bits (151), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 46/151 (30%), Positives = 79/151 (52%), Gaps = 11/151 (7%) Query: 124 ALSFNAFKTVMDIDTSGTFNVSR-VLYEKFFRDHGGVIV---NITATLGNRGQALQVHAG 179 ALS + + V+ + +NV + + GG I+ +++ +GNRGQ V+ Sbjct: 122 ALSNDDWDAVIHTNLDSFYNVIQPCIMPMIGARQGGRIITLSSVSGVMGNRGQ---VNYS 178 Query: 180 SAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRL 239 +AKA + T+ LA+E + I VN +APG I G+ + +++L ++ P++R+ Sbjct: 179 AAKAGIIGATKALAIELAKRKITVNCIAPGLID--TGMIEM--EESALKEAMSMIPMKRM 234 Query: 240 GNKTEIAHSVLYLASPLASYVTGAVLVADGG 270 G E+A YL S +A YVT V+ +GG Sbjct: 235 GQAEEVAGLASYLMSDIAGYVTRQVISINGG 265 >5YSS-A nrPDB Length = 256 Score = 62.4 bits (150), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 62/256 (24%), Positives = 108/256 (42%), Gaps = 12/256 (4%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L K A +TG SGIG IA++ + G ++ + AA+ G+ Sbjct: 3 LTGKTALVTGSTSGIGLGIAQVLAQAGATLILNGFG---DVDAAKDAVAQYGKTPGYHGA 59 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 D+ + + A EFG +DILIN A + P + + ++ I+ S F+ + Sbjct: 60 DLSDEAQIADMMRYAESEFGGVDILINNAGIQHVSPIETFPVDKWNAIIAINLSSVFHTT 119 Query: 146 RVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNS 205 R+ + G I+NI + G + +AK V +T+ +A+E I N+ Sbjct: 120 RLALPGMRARNWGRIINIASVHGLVASKEKSAYVAAKHGVVGLTKTIALETAQTEITCNA 179 Query: 206 LAPG----PISGTEGLRRL---GGPQASLSTKVTA-SPLQRLGNKTEIAHSVLYLASPLA 257 L PG P+ + +R+ P+A+ + P + ++ + L+L S A Sbjct: 180 LCPGWVLTPLVQQQIDKRIAEGAEPEAARDALLAEKQPSREFVTPEQLGNLALFLCSDGA 239 Query: 258 SYVTGAVLVADGGAWL 273 + V G DGG W+ Sbjct: 240 AQVRGVAWNMDGG-WV 254 >4CR6-A nrPDB Length = 271 Score = 62.4 bits (150), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 74/260 (28%), Positives = 116/260 (44%), Gaps = 24/260 (9%) Query: 23 PDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLP 82 P L K A +TG GIG E ++R G +V+A PR+ + GA +P Sbjct: 10 PGRLAGKAAIVTGAAGGIGRATVEAYLREGA-SVVAMDLAPRLAATRYEEPGA-----IP 63 Query: 83 LSMDVRAPPAVMAAVDQALKEFGRIDILINCAA-----GNFLCPAGALSFNAFKTVMDID 137 ++ D+ A+ AA+ A+ G +DIL+ A GNFL LS + +D++ Sbjct: 64 IACDLADRAAIDAAMADAVARLGGLDILVAGGALKGGTGNFL----DLSDADWDRYVDVN 119 Query: 138 TSGTFNVSRVLYEKFFRDHGGV------IVNITATLGNRGQALQVHAGSAKAAVDAMTRH 191 +GTF R G I+ I + + +AK V +TR Sbjct: 120 MTGTFLTCRAGARAMVAAGAGKDGRSARIITIGSVNSFMAEPEAAAYVAAKGGVAMLTRA 179 Query: 192 LAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTAS-PLQRLGNKTEIAHSVL 250 +AV+ I VN +APGP+ T G + L+ +V L R G E+A + + Sbjct: 180 MAVDLARHGILVNMIAPGPVDVTG--NNTGYSEPRLAEQVLDEVALGRPGLPEEVATAAV 237 Query: 251 YLASPLASYVTGAVLVADGG 270 +LA +S++TG+ + DGG Sbjct: 238 FLAEDGSSFITGSTITIDGG 257 >3PPI-A nrPDB Length = 281 Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 70/261 (26%), Positives = 114/261 (43%), Gaps = 31/261 (11%) Query: 31 AFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAP 90 A ++GG G+G G VIA + + + LA G R +S +V + Sbjct: 33 AIVSGGAGGLGEATVRRLHADGLGVVIADLAAEK----GKALADELGNRAEFVSTNVTSE 88 Query: 91 PAVMAAVDQALKEFGRIDILINCAAGNFLC----------PAGALSFNAFKTVMDIDTSG 140 +V+AA++ A + GR+ + A G F PA F +D+ +G Sbjct: 89 DSVLAAIEAA-NQLGRLRYAV-VAHGGFGVAQRIVQRDGSPA---DMGGFTKTIDLYLNG 143 Query: 141 TFNVSRVLYEKFF----RDHG--GVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAV 194 T+NV+R++ R++G G +V + G GQ Q +AKA V +T A Sbjct: 144 TYNVARLVAASIAAAEPRENGERGALVLTASIAGYEGQIGQTAYAAAKAGVIGLTIAAAR 203 Query: 195 EWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPL-QRLGNKTEIAHSVLYLA 253 + IRVN++APG + T + +G + +L+ P +RLG E A + +L Sbjct: 204 DLSSAGIRVNTIAPGTMK-TPIMESVG--EEALAKFAANIPFPKRLGTPDEFADAAAFLL 260 Query: 254 SPLASYVTGAVLVADGGAWLT 274 + Y+ G V+ DG T Sbjct: 261 TN--GYINGEVMRLDGAQRFT 279 >3W8F-A nrPDB Length = 260 Score = 58.5 bits (140), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 57/256 (22%), Positives = 104/256 (40%), Gaps = 10/256 (3%) Query: 25 LLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARK-LAGATGRRCLPL 83 +L+ K A +TG SGIG +A + G VI P + R L G + L Sbjct: 1 MLKGKKAVVTGSTSGIGLAMATELAKAGADVVINGFGQPEDIERERSTLESKFGVKAYYL 60 Query: 84 SMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFN 143 + D+ A + +A + G +DIL+N A P + + ++ ++ S F+ Sbjct: 61 NADLSDAQATRDFIAKAAEALGGLDILVNNAGIQHTAPIEEFPVDKWNAIIALNLSAVFH 120 Query: 144 VSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRV 203 + + G I+NI + G + +AK V +T+ A+E + I Sbjct: 121 GTAAALPIMQKQGWGRIINIASAHGLVASVNKSAYVAAKHGVVGLTKVTALENAGKGITC 180 Query: 204 NSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNK---------TEIAHSVLYLAS 254 N++ PG + +++ + A+ + L K ++ + ++L+S Sbjct: 181 NAICPGWVRTPLVEKQIEAISQQKGIDIEAAARELLAEKQPSLQFVTPEQLGGAAVFLSS 240 Query: 255 PLASYVTGAVLVADGG 270 A +TG L DGG Sbjct: 241 AAADQMTGTTLSLDGG 256 >4ZJU-A nrPDB Length = 275 Score = 58.2 bits (139), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 35/97 (36%), Positives = 53/97 (54%), Gaps = 11/97 (11%) Query: 179 GSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPI-----SGTEGLRRLGGPQASLSTKVTA 233 G AKA+++A R+LA G IRVN+++ GPI SG + R++ L Sbjct: 171 GMAKASLEAGVRYLASSLGVDGIRVNAISAGPIRTLAASGIKSFRKM------LDANEKV 224 Query: 234 SPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVADGG 270 +PL+R E+ ++ L+L SP AS +TG +L D G Sbjct: 225 APLKRNVTIEEVGNAALFLCSPWASGITGEILYVDAG 261 >1BDB-A nrPDB Length = 277 Score = 58.2 bits (139), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 72/261 (27%), Positives = 109/261 (41%), Gaps = 25/261 (9%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L+ + ITGG SG+G + + F+ G + +S R+ +L G L + Sbjct: 3 LKGEAVLITGGASGLGRALVDRFVAEGAKVAVLDKSAERL----AELETDHGDNVLGIVG 58 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILI-NCAAGNFLC-----PAGALSFNAFKTVMDIDTS 139 DVR+ A + + FG+ID LI N ++ P +L AF V I+ Sbjct: 59 DVRSLEDQKQAASRCVARFGKIDTLIPNAGIWDYSTALVDLPEESLD-AAFDEVFHINVK 117 Query: 140 GTFNVSRVLYEKFFRDHGGVIVNITAT--LGNRGQALQVHAGSAKAAVDAMTRHLAVEWG 197 G + + G VI I+ N G L +AK A+ + R LA E Sbjct: 118 GYIHAVKACLPALVASRGNVIFTISNAGFYPNGGGPLYT---AAKHAIVGLVRELAFELA 174 Query: 198 PQNIRVNSLAPGPI-SGTEGLRRLGGPQASLSTKVTAS------PLQRLGNKTEIAHSVL 250 P +RVN + G I S G LG ++ST A P+ R+ E + + Sbjct: 175 PY-VRVNGVGSGGINSDLRGPSSLGMGSKAISTVPLADMLKSVLPIGRMPEVEEYTGAYV 233 Query: 251 YLAS-PLASYVTGAVLVADGG 270 + A+ A+ TGA+L DGG Sbjct: 234 FFATRGDAAPATGALLNYDGG 254 >6CGE-A nrPDB Length = 328 Score = 57.0 bits (136), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 52/204 (25%), Positives = 86/204 (42%), Gaps = 7/204 (3%) Query: 30 VAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLP-----LS 84 V ITG SGIG +A + +L + T R A C P L Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 Query: 85 MDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNV 144 +DVR +V AA ++ + GR+D+L+ A L P AL +A +V+D++ GT + Sbjct: 65 LDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122 Query: 145 SRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVN 204 + R G ++ + G G ++K A++ + LAV P + ++ Sbjct: 123 LQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLS 182 Query: 205 SLAPGPISGTEGLRRLGGPQASLS 228 + GP+ + LG P+ L Sbjct: 183 LIECGPVHTAFMEKVLGSPEEVLD 206 >5O3Z-A nrPDB Length = 263 Score = 57.0 bits (136), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 61/254 (24%), Positives = 101/254 (39%), Gaps = 11/254 (4%) Query: 28 DKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGR-RCLPLSMD 86 ++VA + GGG +G + E + G H +A + A + G R +D Sbjct: 6 EQVAVVIGGGQTLGAFLCEGLAQAGYHVAVADLNESNANRLADTINSRYGAGRAYGFKVD 65 Query: 87 VRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSR 146 +V A + FGR D+L+ A P F + ++ G F SR Sbjct: 66 ATDEASVEALARAVDETFGRADLLVYSAGVAKAAPITQFRLTDFDLSLQVNLVGYFLCSR 125 Query: 147 VLYEKFFRDH-GGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNS 205 + RD G I+ I + G G +AK +T+ LA++ I V+S Sbjct: 126 EFSKLMIRDGIKGRIIQINSKSGKVGSKHNSGYSAAKFGGVGLTQSLALDLAEYGITVHS 185 Query: 206 LAPGPISGT--------EGLRRLG-GPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPL 256 L G + + + +LG P+ V PL+R + ++ + +L+ AS Sbjct: 186 LMLGNLLKSPMFQSLLPQYAEKLGITPEEVEPYYVDKVPLKRGCDYQDVLNVLLFYASDK 245 Query: 257 ASYVTGAVLVADGG 270 A+Y TG + GG Sbjct: 246 AAYCTGQSINVTGG 259 >4NK4-A nrPDB Length = 301 Score = 57.0 bits (136), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 39/120 (32%), Positives = 63/120 (52%), Gaps = 11/120 (9%) Query: 156 HGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTE 215 HGG ++ +T R AK+A+++ T++LA ++G NIR+N+++ GP+ Sbjct: 171 HGGAMITLTYGGSMRVVPNYNAMAPAKSALESSTKYLACDYGGMNIRINAISAGPV---- 226 Query: 216 GLRRLGGPQASLSTKVTA-----SPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVADGG 270 R L G S + A SPL+R + +I +S LYL S L++ VTG + D G Sbjct: 227 --RTLAGASISNGRDIAAWSKENSPLKRTVSLEDIGNSALYLLSYLSNGVTGEIHYVDCG 284 >1A27-A nrPDB Length = 289 Score = 57.0 bits (136), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 52/203 (25%), Positives = 86/203 (42%), Gaps = 7/203 (3%) Query: 30 VAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLP-----LS 84 V ITG SGIG +A + +L + T R A C P L Sbjct: 4 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 63 Query: 85 MDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNV 144 +DVR +V AA ++ + GR+D+L+ A L P AL +A +V+D++ GT + Sbjct: 64 LDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 121 Query: 145 SRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVN 204 + R G ++ + G G ++K A++ + LAV P + ++ Sbjct: 122 LQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLS 181 Query: 205 SLAPGPISGTEGLRRLGGPQASL 227 + GP+ + LG P+ L Sbjct: 182 LIECGPVHTAFMEKVLGSPEEVL 204 >2BGM-A nrPDB Length = 278 Score = 56.6 bits (135), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 80/267 (29%), Positives = 118/267 (44%), Gaps = 18/267 (6%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLP--L 83 L+DKVA ITGG GIG A++F+R+G VIA + +K+ G + + Sbjct: 14 LQDKVAIITGGAGGIGETTAKLFVRYGAKVVIADIADDH----GQKVCNNIGSPDVISFV 69 Query: 84 SMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSF--NAFKTVMDIDTSGT 141 DV V VD + + G++DI+ P L FK VMDI+ G Sbjct: 70 HCDVTKDEDVRNLVDTTIAKHGKLDIMFGNVGVLSTTPYSILEAGNEDFKRVMDINVYGA 129 Query: 142 FNVSRVLYEKFFRDHGGVIVNITATLGN--RGQALQVHAGSAKAAVDAMTRHLAVEWGPQ 199 F V++ G IV TA++ + G+ + + K AV +T L E G Sbjct: 130 FLVAKHAARVMIPAKKGSIV-FTASISSFTAGEGVSHVYTATKHAVLGLTTSLCTELGEY 188 Query: 200 NIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGN---KTEIAHSVLYLASPL 256 IRVN ++P I + L + G +S ++ G ++A +V YLA Sbjct: 189 GIRVNCVSP-YIVASPLLTDVFGVDSSRVEELAHQAANLKGTLLRAEDVADAVAYLAGDE 247 Query: 257 ASYVTGAVLVADGGAWLT---FPNGVK 280 + YV+G LV DGG T FP +K Sbjct: 248 SKYVSGLNLVIDGGYTRTNPAFPTALK 274 >5YCX-A nrPDB Length = 266 Score = 56.2 bits (134), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 61/218 (27%), Positives = 97/218 (44%), Gaps = 18/218 (8%) Query: 63 PRVLTAARKLAGA-TGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAA------ 115 R+ R+LA G+ L L DV + A + +E G I + +C A Sbjct: 44 ERLERNVRELADTLEGQESLVLPCDVTNDEELTACFETIKQEVGTIHGVAHCIAFANRDD 103 Query: 116 --GNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVLYE-KFFRDHGGVIVNITATLGNRGQ 172 G F+ S + F +I F+++ V E K GG I+ +T G R Sbjct: 104 LKGEFVDT----SRDGFLLAQNISA---FSLTAVAREAKKVMTEGGNILTLTYLGGERVV 156 Query: 173 ALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVT 232 G AKA+++A ++LA + G IRVN+++ GPI T + +G + L Sbjct: 157 KNYNVMGVAKASLEASVKYLANDLGQHGIRVNAISAGPIR-TLSAKGVGDFNSILREIEE 215 Query: 233 ASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVADGG 270 +PL+R + E+ + ++L S LA VTG + D G Sbjct: 216 RAPLRRTTTQEEVGDTAVFLFSDLARGVTGENIHVDSG 253 >2DKN-A nrPDB Length = 255 Score = 55.8 bits (133), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 34/102 (33%), Positives = 53/102 (51%), Gaps = 1/102 (0%) Query: 169 NRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLS 228 +GQ +AGS K AV + R V+W + +R+N +APG + P+ S Sbjct: 145 QQGQTHLAYAGS-KYAVTCLARRNVVDWAGRGVRLNVVAPGAVETPLLQASKADPRYGES 203 Query: 229 TKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVADGG 270 T+ +PL R E+A ++ +L P AS++ G+VL DGG Sbjct: 204 TRRFVAPLGRGSEPREVAEAIAFLLGPQASFIHGSVLFVDGG 245 >2PD3-A nrPDB Length = 275 Score = 55.1 bits (131), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 54/199 (27%), Positives = 92/199 (46%), Gaps = 23/199 (11%) Query: 84 SMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGAL-------SFNAFKTVMDI 136 +DV + + K+ G +D +++ A P AL S +AF T M+I Sbjct: 62 ELDVSKEEHFKSLYNSVKKDLGSLDFIVHSVA---FAPKEALEGSLLETSKSAFNTAMEI 118 Query: 137 DTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEW 196 ++ L K ++G ++ ++ + A G AKAA+++ R+LAV+ Sbjct: 119 SVYSLIELTNTL--KPLLNNGASVLTLSYLGSTKYMAHYNVMGLAKAALESAVRYLAVDL 176 Query: 197 GPQNIRVNSLAPGPI-----SGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLY 251 G +IRVN+L+ GPI SG R + L +PL++ + E+ ++ +Y Sbjct: 177 GKHHIRVNALSAGPIRTLASSGIADFRMI------LKWNEINAPLRKNVSLEEVGNAGMY 230 Query: 252 LASPLASYVTGAVLVADGG 270 L S L+S V+G V D G Sbjct: 231 LLSSLSSGVSGEVHFVDAG 249 >3O26-A nrPDB Length = 311 Score = 55.1 bits (131), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 30/95 (31%), Positives = 50/95 (52%), Gaps = 2/95 (2%) Query: 22 CPDLL-RDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRC 80 CP+ + + + A +TGG GIGF I + +G V+ R + + A KL + Sbjct: 5 CPNTVTKRRCAVVTGGNKGIGFEICKQLSSNGIMVVLTCRDVTKGHEAVEKLKNSNHENV 64 Query: 81 LPLSMDVRAPPAVMAAVDQALK-EFGRIDILINCA 114 + +DV P A M+++ +K FG++DIL+N A Sbjct: 65 VFHQLDVTDPIATMSSLADFIKTHFGKLDILVNNA 99 >4Q9N-A nrPDB Length = 298 Score = 54.3 bits (129), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 77/293 (26%), Positives = 122/293 (41%), Gaps = 60/293 (20%) Query: 26 LRDKVAFITGGG--SGIGFRIAEIFMRHGCHTVIA---------SRSLPR-VLTAARKLA 73 L K+AFI G G +G G+ IA++ G ++ S+SL A+R+L+ Sbjct: 6 LTGKIAFIAGIGDDNGYGWGIAKMLAEAGATILVGTWVPIYKIFSQSLELGKFNASRELS 65 Query: 74 GA---TGRRCLPLSMDVRAPP------------------AVMAAVDQALKEFGRIDILIN 112 T + P+ P V V+Q K FG IDIL++ Sbjct: 66 NGELLTFAKIYPMDASFDTPEDIPQEILENKRYKDLSGYTVSEVVEQVKKHFGHIDILVH 125 Query: 113 CAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVLYEKFFR--DHGGVIVN-----ITA 165 A + P A K ++D G F H G I+N I+ Sbjct: 126 SLANS---PEIA------KPLLDTSRKGYLAALSTSSYSFISLLSHFGPIMNAGASTISL 176 Query: 166 TLGNRGQALQVHAG---SAKAAVDAMTRHLAVE----WGPQNIRVNSLAPGPISGTEGLR 218 T +A+ + G +AKAA+++ T+ LA E WG +RVN+++ GP++ G + Sbjct: 177 TYLASMRAVPGYGGGMNAAKAALESDTKVLAWEAGRRWG---VRVNTISAGPLASRAG-K 232 Query: 219 RLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVADGGA 271 +G + + +PL ++ + +L SPLAS +TG L D GA Sbjct: 233 AIGFIERMVDYYQDWAPLPSPMEAEQVGAAAAFLVSPLASAITGETLYVDHGA 285 >3OIG-A nrPDB Length = 266 Score = 53.5 bits (127), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 38/119 (31%), Positives = 59/119 (49%), Gaps = 1/119 (0%) Query: 156 HGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTE 215 GG IV +T G G AKA++DA ++LA + G +NIRVNS++ GPI T Sbjct: 139 EGGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAADLGKENIRVNSISAGPIR-TL 197 Query: 216 GLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVADGGAWLT 274 + + + L +PL+R E+ + +L S ++ +TG L D G +T Sbjct: 198 SAKGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLFSDMSRGITGENLHVDSGFHIT 256 >4GKB-A nrPDB Length = 258 Score = 53.1 bits (126), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 73/264 (27%), Positives = 111/264 (42%), Gaps = 38/264 (14%) Query: 26 LRDKVAFIT----GGGSGIGFRIAE------IFMRH---GCHTVIASRSLPRVLTAARKL 72 L+DKV +T G G I R+AE +F RH G ++ PR Sbjct: 5 LQDKVVIVTGGASGIGGAISMRLAEERAIPVVFARHAPDGAFLDALAQRQPRATY----- 59 Query: 73 AGATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKT 132 L ++++ AV Q + FGR+D L+N A N A +AF Sbjct: 60 ----------LPVELQDDAQCRDAVAQTIATFGRLDGLVNNAGVNDGIGLDA-GRDAFVA 108 Query: 133 VMDIDTSGTFNVSR--VLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTR 190 ++ + + ++ V + K R G IVNI++ GQ ++K A A+TR Sbjct: 109 SLERNLIHYYAMAHYCVPHLKATR---GAIVNISSKTAVTGQGNTSGYCASKGAQLALTR 165 Query: 191 HLAVEWGPQNIRVNSLAPGPISG---TEGLRRLGGPQASLSTKVTASPL-QRLGNKTEIA 246 AV +RVN++ P + + P+A L+ PL +R EIA Sbjct: 166 EWAVALREHGVRVNAVIPAEVMTPLYRNWIATFEDPEAKLAEIAAKVPLGRRFTTPDEIA 225 Query: 247 HSVLYLASPLASYVTGAVLVADGG 270 + ++L SP AS+ TG L DGG Sbjct: 226 DTAVFLLSPRASHTTGEWLFVDGG 249 >3OML-A nrPDB Length = 613 Score = 53.1 bits (126), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 49/202 (24%), Positives = 84/202 (41%), Gaps = 20/202 (9%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVI------------ASRSLPRVLTAARKLAGAT 76 +VA +TG G+G+G A +F G V+ + R+ V+ RK G Sbjct: 20 RVAVVTGAGAGLGREYALLFAERGAKVVVNDLGGTHSGDGASQRAADIVVDEIRKAGGEA 79 Query: 77 GRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDI 136 D + ++ A+K FGR+DIL+N A S + V D+ Sbjct: 80 -------VADYNSVIDGAKVIETAIKAFGRVDILVNNAGILRDRSLVKTSEQDWNLVNDV 132 Query: 137 DTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEW 196 G+F ++ + + + G I+ ++ G G QV+ +AK + + +A+E Sbjct: 133 HLKGSFKCTQAAFPYMKKQNYGRIIMTSSNSGIYGNFGQVNYTAAKMGLIGLANTVAIEG 192 Query: 197 GPQNIRVNSLAPGPISG-TEGL 217 N+ N + P S TEG+ Sbjct: 193 ARNNVLCNVIVPTAASRMTEGI 214 >1P33-A nrPDB Length = 289 Score = 53.1 bits (126), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 59/209 (28%), Positives = 86/209 (41%), Gaps = 42/209 (20%) Query: 95 AAVDQALKEFGRIDILINCAAGNFLCP-------AGALSFNAFKT--VMDIDTSGTFNVS 145 A VD +GR D+L+N A+ + P G S ++ V D G+ ++ Sbjct: 92 ALVDACYMHWGRCDVLVNNASSFYPTPLLRKDAGEGGSSVGDKESLEVAAADLFGSNAIA 151 Query: 146 RVLYEKFF-----------RDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAV 194 K F R IVN+ + ++ AK A++ +TR A+ Sbjct: 152 PYFLIKAFAQRVADTRAEQRGTSYSIVNMVDAMTSQPLLGYTMYTMAKEALEGLTRSAAL 211 Query: 195 EWGPQNIRVNSLAPG--------PISGTEGLRRLGGPQASLSTKVTASPL-QRLGNKTEI 245 E IRVN ++PG P S E RR KV PL QR + E+ Sbjct: 212 ELASLQIRVNGVSPGLSVLPDDMPFSVQEDYRR----------KV---PLYQRNSSAEEV 258 Query: 246 AHSVLYLASPLASYVTGAVLVADGGAWLT 274 + V++L SP A Y+TG + DGG LT Sbjct: 259 SDVVIFLCSPKAKYITGTCIKVDGGYSLT 287 >4NR0-A nrPDB Length = 273 Score = 52.8 bits (125), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 33/97 (34%), Positives = 54/97 (55%), Gaps = 11/97 (11%) Query: 179 GSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPI-----SGTEGLRRLGGPQASLSTKVTA 233 G AKA+++A R+LA G + RVN+++ GPI SG + R++ L+ Sbjct: 163 GMAKASLEAGVRYLAGSLGAEGTRVNAVSAGPIRTLAASGIKSFRKM------LAANERQ 216 Query: 234 SPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVADGG 270 +PL+R E+ ++ +L S LAS ++G +L DGG Sbjct: 217 TPLRRNVTIEEVGNAGAFLCSDLASGISGEILYVDGG 253 >5CFZ-A nrPDB Length = 305 Score = 52.8 bits (125), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 64/281 (22%), Positives = 120/281 (42%), Gaps = 44/281 (15%) Query: 18 RHLFCPDL---LRDKVAFITG---------GGSGIGFRIAEIFMRHGCHTVIASRSLPRV 65 +H+ PDL DK+ F++G I + IA+ R G ++ Sbjct: 29 QHMDSPDLGTDDDDKMGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQN---- 84 Query: 66 LTAARKLAGATGRRCLPLSMDV--RAPPAVMAAVDQALKEFGRI----DILINC---AAG 116 KL G L D+ + A A++D E G++ D ++ A G Sbjct: 85 ----DKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPG 140 Query: 117 NFLC--PAGALSFNAFKTVMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQAL 174 + L A++ FK DI + +++ + + G ++ ++ R Sbjct: 141 DQLDGDYVNAVTREGFKIAHDISSYSFVAMAKAC--RSMLNPGSALLTLSYLGAERAIPN 198 Query: 175 QVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPI-----SGTEGLRRLGGPQASLST 229 G AKA+++A R++A GP+ +RVN+++ GPI SG + R++ L+ Sbjct: 199 YNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKM------LAH 252 Query: 230 KVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVADGG 270 +P++R ++ +S +L S L++ ++G V+ DGG Sbjct: 253 CEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGG 293 >4JQC-A nrPDB Length = 282 Score = 52.4 bits (124), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 30/97 (30%), Positives = 56/97 (57%), Gaps = 11/97 (11%) Query: 179 GSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPI-----SGTEGLRRLGGPQASLSTKVTA 233 G AKA+++A R++A GP+ +RVN+++ GPI SG + R++ L+ Sbjct: 180 GLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKM------LAHCEAV 233 Query: 234 SPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVADGG 270 +P++R ++ +S +L S L++ ++G V+ DGG Sbjct: 234 TPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGG 270 >1FJH-A nrPDB Length = 257 Score = 52.0 bits (123), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 38/108 (35%), Positives = 52/108 (48%), Gaps = 2/108 (1%) Query: 163 ITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRLGG 222 I G +G L +AGS K A+ R A WG +R+N++APG L Sbjct: 142 IVEHAGEQGGNL-AYAGS-KNALTVAVRKRAAAWGEAGVRLNTIAPGATETPLLQAGLQD 199 Query: 223 PQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVADGG 270 P+ S P+ R +E+A + +L SP ASYV GA +V DGG Sbjct: 200 PRYGESIAKFVPPMGRRAEPSEMASVIAFLMSPAASYVHGAQIVIDGG 247 >3U9L-A nrPDB Length = 324 Score = 52.0 bits (123), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 44/144 (30%), Positives = 66/144 (45%), Gaps = 6/144 (4%) Query: 25 LLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRS--LPRVLTAARKLAGATGRRCLP 82 ++ K+ ITG SG G AE G H V AS + R + +AG + Sbjct: 2 VMSKKIILITGASSGFGRLTAEALAGAG-HRVYASMRDIVGRNASNVEAIAGFARDNDVD 60 Query: 83 L---SMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTS 139 L +DV++ +V A+DQ + E GRID+LI+ A PA A + F + DI+ Sbjct: 61 LRTLELDVQSQVSVDRAIDQIIGEDGRIDVLIHNAGHMVFGPAEAFTPEQFAELYDINVL 120 Query: 140 GTFNVSRVLYEKFFRDHGGVIVNI 163 T V+R R G+++ I Sbjct: 121 STQRVNRAALPHMRRQKHGLLIWI 144 >2P91-A nrPDB Length = 285 Score = 52.0 bits (123), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 59/252 (23%), Positives = 101/252 (40%), Gaps = 10/252 (3%) Query: 25 LLRDKVAFITG--GGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLP 82 LL K A ITG I + IA+ F R G + + P++ R++A G L Sbjct: 18 LLEGKRALITGVANERSIAYGIAKSFHREGAQLAF-TYATPKLEKRVREIAKGFGSD-LV 75 Query: 83 LSMDVRAPPAVMAAVDQALKEFGRIDILINCAA----GNFLCPAGALSFNAFKTVMDIDT 138 + DV + + +G +DI+++ A F S FK MDI Sbjct: 76 VKCDVSLDEDIKNLKKFLEENWGSLDIIVHSIAYAPKEEFKGGVIDTSREGFKIAMDISV 135 Query: 139 SGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGP 198 ++R L G IV ++ + G AKAA+++ R+LA + Sbjct: 136 YSLIALTRELL-PLMEGRNGAIVTLSYYGAEKVVPHYNVMGIAKAALESTVRYLAYDIAK 194 Query: 199 QNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLAS 258 R+N+++ GP+ T + G + +P + ++ + ++L S A Sbjct: 195 HGHRINAISAGPVK-TLAAYSITGFHLLMEHTTKVNPFGKPITIEDVGDTAVFLCSDWAR 253 Query: 259 YVTGAVLVADGG 270 +TG V+ D G Sbjct: 254 AITGEVVHVDNG 265 >5L51-A nrPDB Length = 324 Score = 51.6 bits (122), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 31/93 (33%), Positives = 45/93 (48%), Gaps = 4/93 (4%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTA----ARKLAGATGRRCLPLS 84 + A +TG GIGF I + G ++ASR R + A ++L G + Sbjct: 16 RYAVVTGANKGIGFEICKQLASKGITVILASRDEKRGIEARERLIKELGSEFGDYVVSQQ 75 Query: 85 MDVRAPPAVMAAVDQALKEFGRIDILINCAAGN 117 +DV P +V A VD +FG +DIL+N A N Sbjct: 76 LDVADPASVAALVDFIKTKFGSLDILVNNAGLN 108 >4J3F-A nrPDB Length = 280 Score = 51.6 bits (122), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 30/97 (30%), Positives = 53/97 (54%), Gaps = 11/97 (11%) Query: 179 GSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPI-----SGTEGLRRLGGPQASLSTKVTA 233 G AKA+++A R+ A+ G I+VN+++ GPI SG +++ L Sbjct: 180 GVAKASLEATVRYTALALGEDGIKVNAVSAGPIKTLAASGISNFKKM------LDYNAMV 233 Query: 234 SPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVADGG 270 SPL++ + E+ ++V +L S +A+ +TG V+ D G Sbjct: 234 SPLKKNVDIMEVGNTVAFLCSDMATGITGEVVHVDAG 270 >5I9N-A nrPDB Length = 276 Score = 51.2 bits (121), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 34/94 (36%), Positives = 52/94 (55%), Gaps = 5/94 (5%) Query: 179 GSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPIS--GTEGLRRLGGPQASLSTKVTASPL 236 G AKAA++A R+LAV G + +RVN+++ GPI G++ G L + SPL Sbjct: 160 GLAKAALEASVRYLAVSLGAKGVRVNAISAGPIKTLAASGIKSFGKI---LDFVESNSPL 216 Query: 237 QRLGNKTEIAHSVLYLASPLASYVTGAVLVADGG 270 +R ++ ++ +L S LAS VT V+ D G Sbjct: 217 KRNVTIEQVGNAGAFLLSDLASGVTAEVMHVDSG 250 >5ILO-A nrPDB Length = 271 Score = 50.4 bits (119), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 66/253 (26%), Positives = 106/253 (41%), Gaps = 22/253 (8%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGAT-GRRCLPLS 84 R K A +TGG GIG ++++ + G V A L L KL A + + + Sbjct: 13 FRGKNAVVTGGAGGIGLQVSKQLLAAGAAKV-AIIDLQDNLEEFVKLRAAHPTQSVMIIK 71 Query: 85 MDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNV 144 MDV V A ++ K FG IDI++N AG + + + ++ G N Sbjct: 72 MDVANKKGVEATYEEIAKTFGNIDIVVNV--------AGIFNDKDVQRTLLVNLGGIINS 123 Query: 145 SRVLYEKFFRDH---GGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVE--WGPQ 199 + +D+ GG++VN+++ +G + G+ KA + TR LA E + Sbjct: 124 TLSALPYMGKDNGGKGGIVVNMSSVVGLDPMFIIPVYGATKAGIINFTRCLANEKYYQRS 183 Query: 200 NIRVNSLAPGPISG---TEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPL 256 I+ ++ PG T ++ P+ S T L RL NK A + + L Sbjct: 184 GIKFVTVCPGATMTDMFTNFTEKIIFPETSDE---TYRILDRL-NKQSAADVSRCILNVL 239 Query: 257 ASYVTGAVLVADG 269 GAV V +G Sbjct: 240 EKDKNGAVYVIEG 252 >2QHX-A nrPDB Length = 328 Score = 49.3 bits (116), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 50/193 (25%), Positives = 80/193 (41%), Gaps = 26/193 (13%) Query: 103 EFGRIDILINCAAGNFLCPA------GALSFNAFKTVMDIDTSGTFNVSRV----LYEKF 152 +GR D+L+N A+ + P G + M+ T+ F + + L + F Sbjct: 139 HWGRCDVLVNNASSFYPTPLLRNDEDGHEPCVGDREAMETATADLFGSNAIAPYFLIKAF 198 Query: 153 FRDHGGV----------IVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIR 202 G I+N+ + N+ AK A++ +TR A+E P IR Sbjct: 199 AHRVAGTPAKHRGTNYSIINMVDAMTNQPLLGYTIYTMAKGALEGLTRSAALELAPLQIR 258 Query: 203 VNSLAPGPISGTEGLRRLGGPQASLSTKVTASPL-QRLGNKTEIAHSVLYLASPLASYVT 261 VN + PG + + P A + PL QR + E++ V++L S A Y+T Sbjct: 259 VNGVGPGLSVLVDDM-----PPAVWEGHRSKVPLYQRDSSAAEVSDVVIFLCSSKAKYIT 313 Query: 262 GAVLVADGGAWLT 274 G + DGG LT Sbjct: 314 GTCVKVDGGYSLT 326 >2BFA-A nrPDB Length = 288 Score = 49.3 bits (116), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 50/193 (25%), Positives = 80/193 (41%), Gaps = 26/193 (13%) Query: 103 EFGRIDILINCAAGNFLCPA------GALSFNAFKTVMDIDTSGTFNVSRV----LYEKF 152 +GR D+L+N A+ + P G + M+ T+ F + + L + F Sbjct: 99 HWGRCDVLVNNASSFYPTPLLRNDEDGHEPCVGDREAMETATADLFGSNAIAPYFLIKAF 158 Query: 153 FRDHGGV----------IVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIR 202 G I+N+ + N+ AK A++ +TR A+E P IR Sbjct: 159 AHRVAGTPAKHRGTNYSIINMVDAMTNQPLLGYTIYTMAKGALEGLTRSAALELAPLQIR 218 Query: 203 VNSLAPGPISGTEGLRRLGGPQASLSTKVTASPL-QRLGNKTEIAHSVLYLASPLASYVT 261 VN + PG + + P A + PL QR + E++ V++L S A Y+T Sbjct: 219 VNGVGPGLSVLVDDM-----PPAVWEGHRSKVPLYQRDSSAAEVSDVVIFLCSSKAKYIT 273 Query: 262 GAVLVADGGAWLT 274 G + DGG LT Sbjct: 274 GTCVKVDGGYSLT 286 >4DA9-A nrPDB Length = 280 Score = 48.9 bits (115), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 54/199 (27%), Positives = 84/199 (42%), Gaps = 7/199 (3%) Query: 77 GRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSF--NAFKTVM 134 G R + L D+ + A VD + EFGRID L+N A + L F T++ Sbjct: 78 GARVIFLRADLADLSSHQATVDAVVAEFGRIDCLVNNAGIASIVRDDFLDLKPENFDTIV 137 Query: 135 DIDTSGT-FNVSRVLYEKFFRDHGG--VIVNITATLGNRGQALQVHAGSAKAAVDAMTRH 191 ++ GT F VL D I+NIT+ ++ +KA + A ++ Sbjct: 138 GVNLRGTVFFTQAVLKAMLASDARASRSIINITSVSAVMTSPERLDYCMSKAGLAAFSQG 197 Query: 192 LAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLY 251 LA+ I V + PG I G + + + P++R G +I + V Sbjct: 198 LALRLAETGIAVFEVRPGIIRSDMTAAVSGKYDGLIESGLV--PMRRWGEPEDIGNIVAG 255 Query: 252 LASPLASYVTGAVLVADGG 270 LA + TG+V+ ADGG Sbjct: 256 LAGGQFGFATGSVIQADGG 274 >3UCF-A nrPDB Length = 223 Score = 47.8 bits (112), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 67/250 (26%), Positives = 105/250 (42%), Gaps = 36/250 (14%) Query: 28 DKVAFIT-GGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMD 86 DK ++ GG SGIG +A+ +ASR TG +D Sbjct: 5 DKTVYVVLGGTSGIGAELAKQLESEHTIVHVASRQ--------------TG-------LD 43 Query: 87 VRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAG-ALSFNAFKTVMDIDTSGTFNVS 145 + +V + G D LI AG++ PAG + + DT V Sbjct: 44 ISDEKSVY----HYFETIGAFDHLI-VTAGSY-APAGKVVDVEVTQAKYAFDTKFWGAVL 97 Query: 146 RVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNS 205 + + GG I + L + A + AA++A T+ LA E P IRVN+ Sbjct: 98 AAKHGARYLKQGGSITLTSGMLSRKVVANTYVKAAINAAIEATTKVLAKELAP--IRVNA 155 Query: 206 LAPGPISGTEGLRRLGGPQASLSTKVTAS--PLQRLGNKTEIAHSVLYLASPLASYVTGA 263 ++PG ++ TE + + + T S P+ ++G ++IA + YL + SY+TG Sbjct: 156 ISPG-LTKTEAYKGMNADDRDAMYQRTQSHLPVGKVGEASDIA--MAYLFAIQNSYMTGT 212 Query: 264 VLVADGGAWL 273 V+ DGGA L Sbjct: 213 VIDVDGGALL 222 >4RGB-A nrPDB Length = 294 Score = 46.6 bits (109), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 64/267 (23%), Positives = 104/267 (38%), Gaps = 22/267 (8%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTV---------IASRSL--PRVLTAARKLAG 74 L +V FITG G G A + G + V I L L +L Sbjct: 23 LDGRVVFITGAARGQGRSHAVMCAEQGANIVGVDICEDIDIVPYKLGTYEELEETARLVE 82 Query: 75 ATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVM 134 TG+ L DVR + D +++FG ID +I A P + A + + Sbjct: 83 KTGQEMLFRKADVRDKAVLQEVFDAGVEQFGHIDTVIANAGVVLTNPDERDASEALRLGL 142 Query: 135 DIDTSGTFNVSRVLYEKF-FRDHGGVIVNITATLG----NRGQALQVHAGSAKAAVDAMT 189 DI G +N +V R GG ++ ++ + G+ ++K A+ + Sbjct: 143 DIMLIGVWNTFQVAIPHMKERGQGGNLIATSSMIALLDLTDGRGGTDAYLTSKLAITGLV 202 Query: 190 RHLAVEWGPQNIRVNSLAPGP-----ISGTEGLRRLGGPQASLSTKV-TASPLQRLGNKT 243 R A+ IRVN +AP I+ L ++ L + TA P + Sbjct: 203 RSYALMLAADRIRVNGVAPTNCSTPMITENPALFKVIEENPHLVNAMSTALPDFPMIEPR 262 Query: 244 EIAHSVLYLASPLASYVTGAVLVADGG 270 ++++++L+L S TG+VL D G Sbjct: 263 DVSNAILFLISDAGRSFTGSVLKVDAG 289 >3K2E-A nrPDB Length = 296 Score = 46.6 bits (109), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 32/97 (32%), Positives = 48/97 (49%), Gaps = 11/97 (11%) Query: 179 GSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPI-----SGTEGLRRLGGPQASLSTKVTA 233 G KAA++A ++LAV+ G Q IRVN+++ GP+ SG + L+ Sbjct: 183 GVCKAALEASVKYLAVDLGKQQIRVNAISAGPVRTLASSGISDFHYI------LTWNKYN 236 Query: 234 SPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVADGG 270 SPL+R ++ + LYL S L TG + D G Sbjct: 237 SPLRRNTTLDDVGGAALYLLSDLGRGTTGETVHVDCG 273 >3RKU-A nrPDB Length = 287 Score = 46.2 bits (108), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 56/248 (22%), Positives = 100/248 (40%), Gaps = 12/248 (4%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHG---CHTVIASRSLPRVLTAARKLAGA-TGRRCL 81 L K ITG +GIG A ++ ++A+R L ++ + + + Sbjct: 31 LAKKTVLITGASAGIGKATALEYLEASNGDMKLILAARRLEKLEELKKTIDQEFPNAKVH 90 Query: 82 PLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCP--AGALSFNAFKTVMDIDTS 139 +D+ + ++ +EF IDIL+N A G L G ++ + V D + + Sbjct: 91 VAQLDITQAEKIKPFIENLPQEFKDIDILVNNA-GKALGSDRVGQIATEDIQDVFDTNVT 149 Query: 140 GTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQ 199 N+++ + F + G IVN+ + G ++K AV A T L E Sbjct: 150 ALINITQAVLPIFQAKNSGDIVNLGSIAGRDAYPTGSIYCASKFAVGAFTDSLRKELINT 209 Query: 200 NIRVNSLAPGPISGTEGLRRL-GGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLAS 258 IRV +APG + L R G + + + +PL ++A ++Y S + Sbjct: 210 KIRVILIAPGLVETEFSLVRYRGNEEQAKNVYKDTTPLM----ADDVADLIVYATSRKQN 265 Query: 259 YVTGAVLV 266 V L+ Sbjct: 266 TVIADTLI 273 >2X9N-A nrPDB Length = 288 Score = 46.2 bits (108), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 66/270 (24%), Positives = 109/270 (40%), Gaps = 37/270 (13%) Query: 31 AFITGGGSGIGFRIAEIFMRHGCHTVI-------ASRSLPRVLTAARKLAGATGRRCLPL 83 A +TG IG IA + G VI A+ SL L R + L Sbjct: 26 AVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTN 85 Query: 84 SMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCP--AGALSFNAFKTVMDIDTSGT 141 S + P + ++ + FGR D+L+N A+ + P G N+ ++ + Sbjct: 86 SNVL--PASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGDHEDNSNGKTVETQVAEL 143 Query: 142 FNVSRV----LYEKFFRDHGGVIVNITAT---LGNRGQALQVHAGSA-------KAAVDA 187 + + L F + G N T++ + N A+ A K A+ Sbjct: 144 IGTNAIAPFLLTMSFAQRQKGTNPNCTSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVG 203 Query: 188 MTRHLAVEWGPQNIRVNSLAPG----PISGTEGLRRLGGPQASLSTKVTASPLQRLGNKT 243 +T+ A+E P IRVN +APG P++ E + + L +R + Sbjct: 204 LTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLG--------RREASAE 255 Query: 244 EIAHSVLYLASPLASYVTGAVLVADGGAWL 273 +IA +V++L S A Y+TG+++ DGG L Sbjct: 256 QIADAVIFLVSGSAQYITGSIIKVDGGLSL 285 >2PTG-A nrPDB Length = 319 Score = 44.3 bits (103), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 32/97 (32%), Positives = 50/97 (51%), Gaps = 6/97 (6%) Query: 180 SAKAAVDAMTRHLAVEWG-PQNIRVNSLAPGPIS--GTEGLRRLGGP---QASLSTKVTA 233 SAKAA+++ R LA E G + +RVN ++ GP+ + + G ++ Sbjct: 208 SAKAALESDCRTLAFEAGRARAVRVNCISAGPLKSRAASAIGKAGDKTFIDLAIDYSEAN 267 Query: 234 SPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVADGG 270 +PLQ+ ++ + L+L SPLA VTGA L D G Sbjct: 268 APLQKELESDDVGRAALFLLSPLARAVTGATLYVDNG 304 >2O2S-A nrPDB Length = 315 Score = 43.9 bits (102), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 32/99 (32%), Positives = 52/99 (52%), Gaps = 10/99 (10%) Query: 180 SAKAAVDAMTRHLAVEWGPQ-NIRVNSLAPGPIS-------GTEGLRRLGGPQASLSTKV 231 SAKAA+++ TR LA E G + +RVN+++ GP+ G G + ++ Sbjct: 195 SAKAALESDTRTLAWEAGQKYGVRVNAISAGPLKSRAASAIGKSGEKSF--IDYAIDYSY 252 Query: 232 TASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVADGG 270 +PL+R + ++ + L+L SPLA V+G L D G Sbjct: 253 NNAPLRRDLHSDDVGGAALFLLSPLARAVSGVTLYVDNG 291 >5LCX-A nrPDB Length = 316 Score = 43.9 bits (102), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 32/107 (29%), Positives = 50/107 (46%), Gaps = 4/107 (3%) Query: 28 DKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKL---AGATGRRCLPLS 84 + A +TG GIGF I G ++ SR+ R L A +KL + R + Sbjct: 7 QRYALVTGANKGIGFEICRQLAEKGIIVILTSRNEKRGLEARQKLLKELNVSENRLVFHQ 66 Query: 85 MDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALS-FNAF 130 +DV +V A +FG++DIL+N A + + G +S FN + Sbjct: 67 LDVTDLASVAAVAVFIKSKFGKLDILVNNAGVSGVEMVGDVSVFNEY 113 >4M89-A nrPDB Length = 261 Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 32/97 (32%), Positives = 49/97 (50%), Gaps = 11/97 (11%) Query: 179 GSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPI-----SGTEGLRRLGGPQASLSTKVTA 233 G AKA+++A R A G + IR N ++ GPI SG +L G A+ Sbjct: 161 GMAKASLEAGIRFTAACLGKEGIRCNGISAGPIKTLAASGIADFGKLLGHVAA------H 214 Query: 234 SPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVADGG 270 +PL+R E+ ++ +L S L+S +TG + DGG Sbjct: 215 NPLRRNVTIEEVGNTAAFLLSDLSSGITGEITYVDGG 251 >3E9N-A nrPDB Length = 245 Score = 43.1 bits (100), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 46/187 (24%), Positives = 76/187 (40%), Gaps = 9/187 (4%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L+ K+A +TG G+G I + R H V A P L A ++ G P+ Sbjct: 3 LKKKIAVVTGATGGMGIEIVKDLSRD--HIVYALGRNPEHLAALAEIEGVE-----PIES 55 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 D+ VD+ LK +D L++ AA A S + +D++ +S Sbjct: 56 DIVKEVLEEGGVDK-LKNLDHVDTLVHAAAVARDTTIEAGSVAEWHAHLDLNVIVPAELS 114 Query: 146 RVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNS 205 R L R G ++ I + GN ++K A+ + E IRV++ Sbjct: 115 RQLL-PALRAASGCVIYINSGAGNGPHPGNTIYAASKHALRGLADAFRKEEANNGIRVST 173 Query: 206 LAPGPIS 212 ++PGP + Sbjct: 174 VSPGPTN 180 >2GDZ-A nrPDB Length = 267 Score = 43.1 bits (100), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 47/192 (24%), Positives = 80/192 (41%), Gaps = 10/192 (5%) Query: 25 LLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATG-RRCLPL 83 ++ KVA +TG GIG AE + G + +L + L ++ L + Sbjct: 4 MVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALHEQFEPQKTLFI 63 Query: 84 SMDVRAPPAVMAAVDQALKEFGRIDILINCA-AGNFLCPAGALSFNAFKTVMDIDTSGTF 142 DV + + + FGR+DIL+N A N L N + SGT+ Sbjct: 64 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVI-----SGTY 118 Query: 143 NVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQN-- 200 + K GG+I+N+++ G A Q ++K + TR A+ N Sbjct: 119 -LGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSG 177 Query: 201 IRVNSLAPGPIS 212 +R+N++ PG ++ Sbjct: 178 VRLNAICPGFVN 189 >4DRY-A nrPDB Length = 281 Score = 43.1 bits (100), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 57/230 (24%), Positives = 97/230 (42%), Gaps = 26/230 (11%) Query: 44 IAEIFMRHGCHTVIASRSLPRVLTAAR-KLAGATGRRCLPLSMDVRAPPAVMAAVDQALK 102 IA+ G VI R P VL AA ++ G TG + DV P V A Sbjct: 49 IAQALSAEGYSVVITGRR-PDVLDAAAGEIGGRTGNIVRAVVCDVGDPDQVAALFAAVRA 107 Query: 103 EFGRIDILINCAAGNF-LCPAGALSFNAFKTVMDIDTSGTFNVSRVLYE--KFFRDHGGV 159 EF R+D+L+N A N P ++F + ++ + +G F ++ + K GG Sbjct: 108 EFARLDLLVNNAGSNVPPVPLEEVTFEQWNGIVAANLTGAFLCTQHAFRMMKAQTPRGGR 167 Query: 160 IVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRR 219 I+N + + + K A+ +T+ A++ R++ +A G I Sbjct: 168 IINNGSISAQTPRPNSAPYTATKHAITGLTKSTALDG-----RMHDIACGQID------- 215 Query: 220 LGGPQASLSTKVTASPLQRLGNK--------TEIAHSVLYLAS-PLASYV 260 +G ++ +++ LQ G IA +V+Y+AS PL++ V Sbjct: 216 IGNAATDMTARMSTGVLQANGEVAAEPTIPIEHIAEAVVYMASLPLSANV 265 >1N5D-A nrPDB Length = 288 Score = 43.1 bits (100), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 42/143 (29%), Positives = 63/143 (44%), Gaps = 4/143 (2%) Query: 29 KVAFITGGGSGIGFRIAEIFMRH-GCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDV 87 +VA +TG GIGF I R V+ +R + R A ++L A G +D+ Sbjct: 5 RVALVTGANKGIGFAIVRDLCRQFAGDVVLTARDVARGQAAVKQLQ-AEGLSPRFHQLDI 63 Query: 88 RAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRV 147 ++ A D KE+G +D+L+N AA F + M + GT NV Sbjct: 64 IDLQSIRALCDFLRKEYGGLDVLVNNAAIAFQLDNPTPFHIQAELTMKTNFMGTRNVCTE 123 Query: 148 LYEKFFRDHGGVIVNITATLGNR 170 L + G V VN+++T G R Sbjct: 124 LL-PLIKPQGRV-VNVSSTEGVR 144 >3KZV-A nrPDB Length = 254 Score = 41.6 bits (96), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 43/184 (23%), Positives = 81/184 (44%), Gaps = 6/184 (3%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVR 88 KV +TG GIG I ++ TV+ + R +KL G R + D+ Sbjct: 3 KVILVTGVSRGIGKSIVDVLFSLDKDTVV--YGVARSEAPLKKLKEKYGDRFFYVVGDIT 60 Query: 89 APPAVMAAVDQALKEFGRIDILI-NCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRV 147 + V+ A+K G+ID L+ N + + NA+K + DI+ ++ + Sbjct: 61 EDSVLKQLVNAAVKGHGKIDSLVANAGVLEPVQNVNEIDVNAWKKLYDINFFSIVSLVGI 120 Query: 148 LYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLA 207 + + +G V+ +++ N + GS+KAA++ LA E + ++ ++A Sbjct: 121 ALPELKKTNGNVVF-VSSDACNMYFSSWGAYGSSKAALNHFAMTLANE--ERQVKAIAVA 177 Query: 208 PGPI 211 PG + Sbjct: 178 PGIV 181 >4HBG-A nrPDB Length = 286 Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust. Identities = 50/236 (21%), Positives = 94/236 (39%), Gaps = 46/236 (19%) Query: 30 VAFITGGGSGIGFRIAEIFMRHGCHTVI---ASRSLPRV----------LTAARKLAGAT 76 VA +TG GIG I + + G +I S+ R L+ R+ A A Sbjct: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 Query: 77 GRRCLPLSMDVRAPPAVMAAVDQA-LKEFGR-----------------IDILINCAAGNF 118 + P +D + + D+ LK+ +++LINCA Sbjct: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 Query: 119 LCPAGALSFNAFKTVMDIDTSGTFNVSRVLYEKFFRDHGG-----------VIVNITATL 167 + + + + +M+++ ++ + + + IVNI++ L Sbjct: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 Query: 168 GNRGQAL---QVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRL 220 + + V++ S KAA+ T LA E P+NIR +++PG + GT+ ++ L Sbjct: 186 HSGKMKVPGTSVYSAS-KAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL 240 >2NTV-A nrPDB Length = 268 Score = 38.9 bits (89), Expect = 0.002, Method: Compositional matrix adjust. Identities = 58/265 (21%), Positives = 102/265 (38%), Gaps = 22/265 (8%) Query: 25 LLRDKVAFITG--GGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLP 82 LL K ++G S I F IA++ G V+ R++ +++A + Sbjct: 3 LLEGKRILVSGIITDSSIAFHIAKVAQEAGAQLVLTGFDRLRLI---QRIADRLPDKAPL 59 Query: 83 LSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTF 142 + +DV+ + ++ E G + L P + N F D S Sbjct: 60 IELDVQNEEHLATLAERVTAEIGEGNKLDGVVHSIGFMPQTGMGTNQFFDAPYEDVSKGI 119 Query: 143 NVSRVLYEKFFR------DHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEW 196 ++S Y + + GG IV + R AK+A++++ R +A E Sbjct: 120 HISTYSYASLAKALLLIMNSGGSIVGMDFD-PTRAMPAYNWMTVAKSALESVNRFVAREA 178 Query: 197 GPQNIRVNSLAPGPISGTEGLRRLG---GPQASLSTKVTASPLQR-------LGNKTEIA 246 G +R N +A GPI +G G +A ++ + + + T +A Sbjct: 179 GKYGVRSNLVAAGPIRTLAMSAIVGGAFGEEAGAQMQLLEEGWDQRAPIGWNMKDPTPVA 238 Query: 247 HSVLYLASPLASYVTGAVLVADGGA 271 +V L S TG+++ ADGGA Sbjct: 239 KTVCALLSEWLPATTGSIIYADGGA 263 >1UN9-A nrPDB Length = 552 Score = 37.4 bits (85), Expect = 0.007, Method: Compositional matrix adjust. Identities = 30/86 (34%), Positives = 43/86 (50%), Gaps = 7/86 (8%) Query: 1 MAQPPPDVEGDDCLPAYRHLFCPDLLRDKVAFITGGGSG-----IGFRIAEIFMRHGCHT 55 +A P ++ + PA R + DL ++ VA I+GGGSG +GF + C Sbjct: 22 IASPWNNLARLESDPAIRIVVRRDLNKNNVAVISGGGSGHEPAHVGFIGKGMLTAAVCGD 81 Query: 56 VIASRSLPRVLTAARKLAGATGRRCL 81 V AS S+ VLTA + + G G CL Sbjct: 82 VFASPSVDAVLTAIQAVTGEAG--CL 105 >3DWF-A nrPDB Length = 276 Score = 37.0 bits (84), Expect = 0.011, Method: Compositional matrix adjust. Identities = 20/59 (33%), Positives = 31/59 (52%), Gaps = 3/59 (5%) Query: 21 FCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRS---LPRVLTAARKLAGAT 76 F P++L+ K +TG GIG IA + G H V+ +RS L +V+ +L A+ Sbjct: 4 FRPEMLQGKKVIVTGASKGIGREIAYHLAKMGAHVVVTARSKEALQKVVARCLELGAAS 62 >2HRB-A nrPDB Length = 274 Score = 36.6 bits (83), Expect = 0.012, Method: Compositional matrix adjust. Identities = 28/91 (30%), Positives = 46/91 (50%), Gaps = 2/91 (2%) Query: 29 KVAFITGGGSGIGFRIA-EIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDV 87 +VA +TG GIG IA E+ + V+ +R + R A ++L A G +D+ Sbjct: 3 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQ-AEGLSPRFHQLDI 61 Query: 88 RAPPAVMAAVDQALKEFGRIDILINCAAGNF 118 ++ A D KE+G +++L+N AA F Sbjct: 62 DDLQSIRALRDFLRKEYGGLNVLVNNAAVAF 92 >3F4B-A nrPDB Length = 323 Score = 36.6 bits (83), Expect = 0.013, Method: Compositional matrix adjust. Identities = 36/148 (24%), Positives = 64/148 (43%), Gaps = 27/148 (18%) Query: 153 FRDHGGVIVNITATLGNRGQALQVHAG---SAKAAVDAMTRHLAVEWGPQ-NIRVNSLAP 208 F + GG +V++T + + + G SAKAA+++ TR LA G + NIR+N+++ Sbjct: 167 FMNSGGSVVSLTYQASQK--VVPGYGGGMSSAKAALESDTRVLAYYLGRKYNIRINTISA 224 Query: 209 GPI---------------------SGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAH 247 GP+ SG + ++ +PL++ T++ Sbjct: 225 GPLKSRAATAINKFNNNQKNNMNSSGETDKQNYSFIDYAIDYSEKYAPLKKKLLSTDVGS 284 Query: 248 SVLYLASPLASYVTGAVLVADGGAWLTF 275 +L S +S VTG + D G + F Sbjct: 285 VASFLLSKESSAVTGQTIYVDNGLNIMF 312 >3BHI-A nrPDB Length = 276 Score = 35.8 bits (81), Expect = 0.021, Method: Compositional matrix adjust. Identities = 28/90 (31%), Positives = 42/90 (46%), Gaps = 2/90 (2%) Query: 30 VAFITGGGSGIGFRIAEIFMR-HGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVR 88 VA +TGG GIG I R V+ +R + R A ++L A G +D+ Sbjct: 6 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQ-AEGLSPRFHQLDID 64 Query: 89 APPAVMAAVDQALKEFGRIDILINCAAGNF 118 ++ A D KE+G +D+L+N A F Sbjct: 65 DLQSIRALRDFLRKEYGGLDVLVNNAGIAF 94 >5PGZ-A nrPDB Length = 276 Score = 35.4 bits (80), Expect = 0.027, Method: Compositional matrix adjust. Identities = 19/61 (31%), Positives = 32/61 (52%), Gaps = 3/61 (4%) Query: 21 FCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRS---LPRVLTAARKLAGATG 77 F P++L+ K +TG GIG +A + G H V+ +RS L +V++ +L A+ Sbjct: 11 FRPEMLQGKKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQKVVSRCLELGAASA 70 Query: 78 R 78 Sbjct: 71 H 71 >4OYR-A nrPDB Length = 289 Score = 33.9 bits (76), Expect = 0.084, Method: Compositional matrix adjust. Identities = 53/250 (21%), Positives = 94/250 (37%), Gaps = 20/250 (8%) Query: 38 SGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAPPAVMAAV 97 S I F IA + G V+ R++ +++ + L +DV+ + + Sbjct: 39 SSIAFHIARVAQEQGAQLVLTGFDRLRLI---QRITDRLPAKAPLLELDVQNEEHLASLA 95 Query: 98 DQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVLYEKFFR--- 154 + + G + L P + N F D S ++S Y + Sbjct: 96 GRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALL 155 Query: 155 ---DHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPI 211 + GG IV + +R AK+A++++ R +A E G +R N +A GPI Sbjct: 156 PIMNPGGSIVGMDFD-PSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPI 214 Query: 212 SGTEGLRRLG---GPQASLSTKVTASPLQR-------LGNKTEIAHSVLYLASPLASYVT 261 +G G +A ++ + + + T +A +V L S T Sbjct: 215 RTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATT 274 Query: 262 GAVLVADGGA 271 G ++ ADGGA Sbjct: 275 GDIIYADGGA 284 >2O2Y-A nrPDB Length = 349 Score = 32.0 bits (71), Expect = 0.33, Method: Compositional matrix adjust. Identities = 16/34 (47%), Positives = 24/34 (70%), Gaps = 1/34 (2%) Query: 179 GSAKAAVDAMTRHLAVEWGPQ-NIRVNSLAPGPI 211 SAKAA+++ TR LA G NIR+N+++ GP+ Sbjct: 199 SSAKAALESDTRVLAYHLGRNYNIRINTISAGPL 232 >1SNY-A nrPDB Length = 267 Score = 30.8 bits (68), Expect = 0.76, Method: Compositional matrix adjust. Identities = 32/106 (30%), Positives = 51/106 (48%), Gaps = 15/106 (14%) Query: 160 IVNITATLG----NRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTE 215 I+N+++ LG N + + ++K+A++A T+ L+V+ PQ I SL PG + Sbjct: 168 IINMSSILGSIQGNTDGGMYAYR-TSKSALNAATKSLSVDLYPQRIMCVSLHPGWVK--- 223 Query: 216 GLRRLGGPQASL----STKVTASPLQRLGNKTEIAHSVLYLASPLA 257 +GG A L ST + +LG K V Y +PLA Sbjct: 224 --TDMGGSSAPLDVPTSTGQIVQTISKLGEKQN-GGFVNYDGTPLA 266 >1KZH-A nrPDB Length = 555 Score = 30.0 bits (66), Expect = 1.1, Method: Compositional matrix adjust. Identities = 16/44 (36%), Positives = 23/44 (52%) Query: 110 LINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVLYEKFF 153 L + G +L + F K++++ D G FNVSRV EK F Sbjct: 355 LSDYMKGVYLSLPLFIQFELIKSILERDPHGNFNVSRVPTEKLF 398 >4NPH-A nrPDB Length = 351 Score = 29.3 bits (64), Expect = 1.9, Method: Compositional matrix adjust. Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 4/62 (6%) Query: 44 IAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAPPAVMAAVDQALKE 103 IAE F +G V+ + SL R AAR++A A G ++ PP V +A+ + L+ Sbjct: 148 IAEFFRDNGKRVVLLADSLTRYARAAREIALAAGE----TAVSGEYPPGVFSALPRLLER 203 Query: 104 FG 105 G Sbjct: 204 TG 205 >4Z3K-A nrPDB Length = 275 Score = 28.9 bits (63), Expect = 2.9, Method: Compositional matrix adjust. Identities = 39/127 (30%), Positives = 53/127 (41%), Gaps = 33/127 (25%) Query: 151 KFFRDHGGV---IVNITATLGNRGQALQVHAGSA-----KAAVDAMTRHLAVEWGPQNIR 202 K F D G+ +VNI++ ALQ G A KAA D + + LA+E N+R Sbjct: 154 KAFPDSPGLNRTVVNISSLC-----ALQPFKGWALYCAGKAARDMLFQVLALE--EPNVR 206 Query: 203 VNSLAPGPISGT---------------EGLRRLGGPQASLSTKVTASPLQRLGNKTEI-- 245 V + APGP+ +GL+ L + KV+A L L K E Sbjct: 207 VLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLEKDEFKS 266 Query: 246 -AHSVLY 251 AH Y Sbjct: 267 GAHVDFY 273 >4HWK-A nrPDB Length = 288 Score = 28.5 bits (62), Expect = 3.3, Method: Compositional matrix adjust. Identities = 39/127 (30%), Positives = 53/127 (41%), Gaps = 33/127 (25%) Query: 151 KFFRDHGGV---IVNITATLGNRGQALQVHAGSA-----KAAVDAMTRHLAVEWGPQNIR 202 K F D G+ +VNI++ ALQ G A KAA D + + LA+E N+R Sbjct: 167 KAFPDSPGLNRTVVNISSLC-----ALQPFKGWALYCAGKAARDMLFQVLALE--EPNVR 219 Query: 203 VNSLAPGPISGT---------------EGLRRLGGPQASLSTKVTASPLQRLGNKTEI-- 245 V + APGP+ +GL+ L + KV+A L L K E Sbjct: 220 VLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLEKDEFKS 279 Query: 246 -AHSVLY 251 AH Y Sbjct: 280 GAHVDFY 286 >2DUN-A nrPDB Length = 133 Score = 28.5 bits (62), Expect = 3.9, Method: Compositional matrix adjust. Identities = 16/67 (23%), Positives = 28/67 (41%) Query: 19 HLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGR 78 +L P + R + AF+TG GFR+ + H V+ S ++ + A Sbjct: 17 YLVEPRMGRSRRAFLTGLARSKGFRVLDACSSEATHVVMEETSAEEAVSWQERRMAAAPP 76 Query: 79 RCLPLSM 85 C P ++ Sbjct: 77 GCTPPAL 83 >2HTF-A nrPDB Length = 105 Score = 28.5 bits (62), Expect = 3.9, Method: Compositional matrix adjust. Identities = 16/64 (25%), Positives = 26/64 (40%) Query: 19 HLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGR 78 +L P + R + AF+TG GFR+ + H V+ S ++ + A Sbjct: 14 YLVEPRMGRSRRAFLTGLARSKGFRVLDACSSEATHVVMEETSAEEAVSWQERRMAAAPP 73 Query: 79 RCLP 82 C P Sbjct: 74 GCTP 77 >2DPY-A nrPDB Length = 438 Score = 28.5 bits (62), Expect = 3.9, Method: Compositional matrix adjust. Identities = 16/42 (38%), Positives = 21/42 (50%) Query: 37 GSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGR 78 G+ RIAE F G H ++ SL R A R++A A G Sbjct: 231 GAAYATRIAEDFRDRGQHVLLIMDSLTRYAMAQREIALAIGE 272 >4IQL-A nrPDB Length = 333 Score = 26.9 bits (58), Expect = 9.8, Method: Compositional matrix adjust. Identities = 14/33 (42%), Positives = 18/33 (54%) Query: 43 RIAEIFMRHGCHTVIASRSLPRVLTAARKLAGA 75 +I EI MR V+ S P+V TA K AG+ Sbjct: 98 KIMEIIMREHVPVVVTSAGSPKVWTAKLKAAGS 130 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4FC7-A nrPDB 343 8e-95 2PNF-A nrPDB 287 5e-78 4JRO-A nrPDB 282 1e-76 3OSU-A nrPDB 273 5e-74 2UVD-A nrPDB 272 1e-73 2HQ1-A nrPDB 270 4e-73 2C07-A nrPDB 266 9e-72 3WOH-A nrPDB 264 5e-71 3RSH-A nrPDB 263 6e-71 1YXM-A nrPDB 263 6e-71 3EMK-A nrPDB 262 1e-70 5ITV-A nrPDB 258 2e-69 3FTP-A nrPDB 256 6e-69 4DMM-A nrPDB 256 7e-69 3LYL-A nrPDB 254 3e-68 4BO1-A nrPDB 254 3e-68 1Q7C-A nrPDB 252 1e-67 1GEE-A nrPDB 252 1e-67 5CDY-A nrPDB 252 2e-67 3AUT-A nrPDB 251 2e-67 3F9I-A nrPDB 251 3e-67 4M8S-A nrPDB 250 5e-67 3GRP-A nrPDB 249 7e-67 3O4R-A nrPDB 248 2e-66 4IIN-A nrPDB 247 6e-66 2PH3-A nrPDB 247 6e-66 6NRP-A nrPDB 245 1e-65 2CDH-G nrPDB 245 2e-65 4K6F-A nrPDB 244 2e-65 4RZH-A nrPDB 244 4e-65 2ZAT-A nrPDB 242 2e-64 4NBV-A nrPDB 240 5e-64 2EW8-A nrPDB 240 5e-64 3OEC-A nrPDB 240 6e-64 3EZL-A nrPDB 239 1e-63 5VT6-A nrPDB 238 2e-63 2NM0-A nrPDB 238 2e-63 4NBT-A nrPDB 238 2e-63 1AE1-A nrPDB 236 7e-63 5U9P-A nrPDB 235 2e-62 2AE2-A nrPDB 234 3e-62 3VZS-A nrPDB 234 4e-62 6CI9-A nrPDB 232 9e-62 3OIC-A nrPDB 231 2e-61 3V2H-A nrPDB 231 2e-61 1GEG-A nrPDB 230 5e-61 4KMS-A nrPDB 229 1e-60 4IIV-A nrPDB 228 2e-60 5OJG-A nrPDB 228 2e-60 4CQL-A nrPDB 228 2e-60 3W8F-A nrPDB 228 2e-60 1X1T-A nrPDB 228 2e-60 4CQM-B nrPDB 227 3e-60 4IS3-A nrPDB 227 4e-60 2Q2Q-A nrPDB 227 5e-60 4DBZ-A nrPDB 227 6e-60 3R3S-A nrPDB 226 8e-60 4Z9Y-A nrPDB 225 1e-59 2B4Q-A nrPDB 224 3e-59 5OVL-A nrPDB 224 4e-59 1AHH-A nrPDB 224 5e-59 3V2G-A nrPDB 223 9e-59 3U5T-A nrPDB 222 1e-58 4MOW-A nrPDB 222 1e-58 5T5Q-A nrPDB 222 2e-58 1K2W-A nrPDB 221 3e-58 5YSS-A nrPDB 221 3e-58 1NFF-A nrPDB 220 4e-58 3WYE-A nrPDB 220 6e-58 5OVJ-A nrPDB 220 7e-58 3UVE-A nrPDB 220 7e-58 1DOH-A nrPDB 219 9e-58 4E6P-A nrPDB 219 1e-57 3T7C-A nrPDB 218 2e-57 2CFC-A nrPDB 217 4e-57 4HP8-A nrPDB 217 5e-57 1W73-A nrPDB 217 5e-57 5B1Y-A nrPDB 216 8e-57 4RZI-B nrPDB 216 9e-57 3WTC-A nrPDB 216 1e-56 3RWB-A nrPDB 215 1e-56 3D3W-A nrPDB 215 2e-56 1UZM-A nrPDB 214 3e-56 3UF0-A nrPDB 214 4e-56 5EJ2-A nrPDB 211 2e-55 1H5Q-A nrPDB 207 4e-54 2HSD-A nrPDB 207 6e-54 3A28-C nrPDB 207 7e-54 5JY1-A nrPDB 204 3e-53 2P91-A nrPDB 202 1e-52 3GDF-A nrPDB 201 2e-52 3V8B-A nrPDB 201 3e-52 4AVY-A nrPDB 200 5e-52 5O3Z-A nrPDB 200 5e-52 3UN1-A nrPDB 200 8e-52 1O5I-A nrPDB 199 1e-51 2FWM-X nrPDB 198 1e-51 3U4C-A nrPDB 198 2e-51 1CYD-A nrPDB 197 4e-51 1HXH-A nrPDB 196 9e-51 5JS6-A nrPDB 195 2e-50 4TRR-A nrPDB 195 2e-50 2AG5-A nrPDB 195 2e-50 4EGF-A nrPDB 194 4e-50 4ALL-A nrPDB 188 2e-48 2X9N-A nrPDB 187 4e-48 2YW9-A nrPDB 187 6e-48 4RGB-A nrPDB 187 7e-48 5YCX-A nrPDB 185 2e-47 5TF4-A nrPDB 183 8e-47 2BGM-A nrPDB 182 1e-46 3OIG-A nrPDB 180 4e-46 3RKU-A nrPDB 180 5e-46 5IZ4-A nrPDB 180 5e-46 3GRK-A nrPDB 179 1e-45 4ZJU-A nrPDB 178 2e-45 4DA9-A nrPDB 178 2e-45 4JQC-A nrPDB 178 3e-45 4CR6-A nrPDB 177 4e-45 2NWQ-A nrPDB 177 5e-45 3ZV3-A nrPDB 177 6e-45 5KOI-A nrPDB 177 7e-45 2QHX-A nrPDB 176 9e-45 2O23-A nrPDB 176 1e-44 5CFZ-A nrPDB 175 3e-44 1E3W-A nrPDB 174 4e-44 2GDZ-A nrPDB 173 5e-44 4NR0-A nrPDB 173 6e-44 1BDB-A nrPDB 173 6e-44 4GKB-A nrPDB 173 9e-44 3K2E-A nrPDB 172 2e-43 1P33-A nrPDB 172 2e-43 4M89-A nrPDB 172 2e-43 4J3F-A nrPDB 171 3e-43 3PXX-A nrPDB 171 3e-43 2BFA-A nrPDB 168 2e-42 3OML-A nrPDB 163 7e-41 5I9N-A nrPDB 160 5e-40 1A27-A nrPDB 160 5e-40 6CGE-A nrPDB 158 2e-39 4NK4-A nrPDB 158 3e-39 3PPI-A nrPDB 152 1e-37 4DRY-A nrPDB 151 4e-37 5ILO-A nrPDB 151 4e-37 2PD3-A nrPDB 149 1e-36 4Q9N-A nrPDB 145 2e-35 1ENP-A nrPDB 141 2e-34 3E9N-A nrPDB 133 7e-32 2O2S-A nrPDB 133 9e-32 3KZV-A nrPDB 130 5e-31 2DKN-A nrPDB 130 8e-31 5L51-A nrPDB 123 1e-28 1N5D-A nrPDB 121 3e-28 3UCF-A nrPDB 121 4e-28 3O26-A nrPDB 119 1e-27 3U9L-A nrPDB 118 3e-27 2PTG-A nrPDB 118 3e-27 1FJH-A nrPDB 115 2e-26 5LCX-A nrPDB 100 8e-22 Sequences not found previously or not previously below threshold: 3DWF-A nrPDB 131 5e-31 5PGZ-A nrPDB 129 1e-30 2HRB-A nrPDB 126 1e-29 4HBG-A nrPDB 125 2e-29 3BHI-A nrPDB 118 4e-27 4OYR-A nrPDB 116 1e-26 2NTV-A nrPDB 111 5e-25 3F4B-A nrPDB 108 3e-24 1SNY-A nrPDB 97 1e-20 1B15-A nrPDB 95 3e-20 2O2Y-A nrPDB 93 2e-19 1MG5-A nrPDB 92 3e-19 4Z3K-A nrPDB 87 6e-18 4HWK-A nrPDB 86 1e-17 1OAA-A nrPDB 86 2e-17 5TQV-A nrPDB 85 5e-17 5WQO-A nrPDB 84 7e-17 4LIS-A nrPDB 76 2e-14 3SLK-A nrPDB 71 4e-13 3ORF-A nrPDB 68 5e-12 1I3M-A nrPDB 57 8e-09 2PK3-A nrPDB 57 9e-09 1Z45-A nrPDB 56 2e-08 3ENK-A nrPDB 54 8e-08 1UDA-A nrPDB 53 1e-07 4G5H-A nrPDB 53 1e-07 2Q1W-A nrPDB 52 3e-07 1OOE-A nrPDB 51 8e-07 1DIR-A nrPDB 50 1e-06 6BWL-A nrPDB 50 1e-06 4J2O-A nrPDB 50 1e-06 2GN9-A nrPDB 50 2e-06 3RFT-A nrPDB 47 1e-05 4R1T-A nrPDB 46 2e-05 3SXP-A nrPDB 46 2e-05 1OC2-A nrPDB 45 3e-05 5B6K-A nrPDB 45 3e-05 1GY8-A nrPDB 44 1e-04 1BXK-A nrPDB 43 2e-04 3PVZ-A nrPDB 43 2e-04 2Z95-A nrPDB 42 3e-04 1GPJ-A nrPDB 42 4e-04 1ZZE-A nrPDB 42 4e-04 1R66-A nrPDB 42 4e-04 6ACF-A nrPDB 41 4e-04 1VL0-A nrPDB 41 5e-04 6GCS-E nrPDB 41 7e-04 3HFS-A nrPDB 41 8e-04 4PVC-A nrPDB 40 0.001 1RKX-A nrPDB 40 0.001 1LU9-A nrPDB 40 0.001 1KEU-A nrPDB 40 0.001 2PZM-A nrPDB 40 0.001 2NNL-D nrPDB 40 0.001 4KTT-E nrPDB 39 0.002 5K1S-A nrPDB 39 0.002 2C20-A nrPDB 39 0.003 3SC6-A nrPDB 39 0.003 2EXX-A nrPDB 38 0.004 1ZDL-A nrPDB 38 0.005 1WVG-A nrPDB 38 0.005 5INT-A nrPDB 38 0.006 5N2I-A nrPDB 38 0.006 3OND-A nrPDB 38 0.006 6ACQ-A nrPDB 38 0.007 4EUF-A nrPDB 37 0.007 3VPX-A nrPDB 37 0.009 4A10-A nrPDB 37 0.012 6DEB-A nrPDB 36 0.013 4PZE-A nrPDB 36 0.015 3LK7-A nrPDB 36 0.018 3NJ4-A nrPDB 36 0.019 1O89-A nrPDB 35 0.028 4KUG-A nrPDB 35 0.032 5YWN-A nrPDB 35 0.043 3ZU2-A nrPDB 35 0.044 3WMX-A nrPDB 35 0.048 1RPN-A nrPDB 35 0.050 4WLE-A nrPDB 35 0.057 2VN8-A nrPDB 35 0.059 1DB3-A nrPDB 34 0.064 3N58-A nrPDB 34 0.069 4K28-A nrPDB 34 0.071 5F5N-A nrPDB 34 0.090 6G2J-P nrPDB 34 0.10 2C54-A nrPDB 33 0.13 3DMF-A nrPDB 33 0.13 5ENV-A nrPDB 33 0.14 1JAY-A nrPDB 33 0.15 4J6F-A nrPDB 33 0.16 2X86-A nrPDB 33 0.17 4FCU-A nrPDB 33 0.17 3RUE-A nrPDB 33 0.18 6C55-A nrPDB 33 0.19 5JXW-A nrPDB 33 0.20 4EJ0-A nrPDB 33 0.20 6GBN-A nrPDB 33 0.22 3DOJ-A nrPDB 32 0.25 2HK7-A nrPDB 32 0.30 2GGS-A nrPDB 32 0.33 1C0L-A nrPDB 32 0.34 3H0K-A nrPDB 32 0.35 3CT4-A nrPDB 32 0.36 2ZJ8-A nrPDB 31 0.41 4WOK-A nrPDB 31 0.42 3X2F-A nrPDB 31 0.43 5GUP-L nrPDB 31 0.43 2DFV-A nrPDB 31 0.45 5UOG-A nrPDB 31 0.51 4B4V-A nrPDB 31 0.52 5EGS-A nrPDB 31 0.53 1U3W-A nrPDB 31 0.53 5M65-A nrPDB 31 0.53 4BKP-A nrPDB 31 0.54 5UZH-A nrPDB 31 0.55 2Q1T-A nrPDB 31 0.56 4CQD-A nrPDB 31 0.62 4EJ6-A nrPDB 31 0.66 3D64-A nrPDB 31 0.66 1ZCJ-A nrPDB 31 0.67 4GBJ-A nrPDB 31 0.70 3HZZ-A nrPDB 31 0.73 3RI6-A nrPDB 31 0.75 2EER-A nrPDB 31 0.75 3H9U-A nrPDB 31 0.81 1N7G-A nrPDB 31 0.81 5LV5-A nrPDB 31 0.87 3R9I-A nrPDB 31 0.87 3ZWA-A nrPDB 31 0.87 2OWO-A nrPDB 30 0.91 5TC4-A nrPDB 30 1.00 3BIC-A nrPDB 30 1.1 4QQR-A nrPDB 30 1.2 1VPD-A nrPDB 30 1.3 4UUP-A nrPDB 30 1.3 4BM5-A nrPDB 30 1.4 6HRD-A nrPDB 30 1.4 4GGP-A nrPDB 30 1.5 3PEF-A nrPDB 30 1.5 6C6P-A nrPDB 30 1.5 4V62-AB nrPDB 30 1.6 6BII-A nrPDB 30 1.6 5NUE-A nrPDB 30 1.6 1IZL-B nrPDB 30 1.6 5HC7-A nrPDB 30 1.6 2IIR-A nrPDB 30 1.8 1E3J-A nrPDB 30 1.9 5GXF-A nrPDB 30 1.9 1Y0Y-A nrPDB 30 2.0 3UMF-A nrPDB 29 2.0 3S8M-A nrPDB 29 2.2 4B4O-A nrPDB 29 2.3 1HSZ-A nrPDB 29 2.4 2ZJ1-A nrPDB 29 2.4 1YXY-A nrPDB 29 2.6 6CL4-A nrPDB 29 2.6 3FBG-A nrPDB 29 2.6 3VR3-A nrPDB 29 2.7 5KIA-A nrPDB 29 2.8 1NHQ-A nrPDB 29 2.8 2BC1-A nrPDB 29 2.8 1F3L-A nrPDB 29 2.8 2WWR-A nrPDB 29 3.0 4E0B-A nrPDB 29 3.0 2X3N-A nrPDB 29 3.2 1YB5-A nrPDB 29 3.3 6BMQ-A nrPDB 28 3.5 2RIR-A nrPDB 28 3.6 1G6Q-1 nrPDB 28 4.0 1X9I-A nrPDB 28 4.1 7REQ-A nrPDB 28 4.2 3HDH-A nrPDB 28 4.4 4W5U-B nrPDB 28 4.5 4A5O-A nrPDB 28 4.7 1VRD-A nrPDB 28 4.7 3K6J-A nrPDB 28 4.8 1F14-A nrPDB 28 4.8 3FFS-A nrPDB 28 4.9 4AP9-A nrPDB 28 5.0 4C5A-A nrPDB 28 5.8 4D3S-A nrPDB 28 5.9 2WEK-A nrPDB 28 5.9 1IM2-A nrPDB 28 5.9 4NPH-A nrPDB 28 6.0 3T69-A nrPDB 28 6.8 5ZVQ-A nrPDB 28 7.1 2XHZ-A nrPDB 27 7.6 2HTF-A nrPDB 27 7.7 4BKO-A nrPDB 27 7.8 1OFI-A nrPDB 27 8.3 1IE3-A nrPDB 27 8.5 5IOB-A nrPDB 27 8.7 4Y4N-A nrPDB 27 9.6 5MH6-A nrPDB 27 9.8 >4FC7-A nrPDB Length = 277 Score = 343 bits (879), Expect = 8e-95, Method: Composition-based stats. Identities = 277/277 (100%), Positives = 277/277 (100%) Query: 2 AQPPPDVEGDDCLPAYRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRS 61 AQPPPDVEGDDCLPAYRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRS Sbjct: 1 AQPPPDVEGDDCLPAYRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRS 60 Query: 62 LPRVLTAARKLAGATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCP 121 LPRVLTAARKLAGATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCP Sbjct: 61 LPRVLTAARKLAGATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCP 120 Query: 122 AGALSFNAFKTVMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSA 181 AGALSFNAFKTVMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSA Sbjct: 121 AGALSFNAFKTVMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSA 180 Query: 182 KAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGN 241 KAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGN Sbjct: 181 KAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGN 240 Query: 242 KTEIAHSVLYLASPLASYVTGAVLVADGGAWLTFPNG 278 KTEIAHSVLYLASPLASYVTGAVLVADGGAWLTFPNG Sbjct: 241 KTEIAHSVLYLASPLASYVTGAVLVADGGAWLTFPNG 277 >2PNF-A nrPDB Length = 248 Score = 287 bits (734), Expect = 5e-78, Method: Composition-based stats. Identities = 75/247 (30%), Positives = 121/247 (48%), Gaps = 3/247 (1%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L+ KV+ +TG GIG IAE G +I S R A ++A G + + M Sbjct: 5 LQGKVSLVTGSTRGIGRAIAEKLASAGSTVIITGTSGERAKAVAEEIANKYGVKAHGVEM 64 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 ++ + ++ A ++ IDIL+N A +S ++ V+ ++ +GTF V+ Sbjct: 65 NLLSEESINKAFEEIYNLVDGIDILVNNAGITRDKLFLRMSLLDWEEVLKVNLTGTFLVT 124 Query: 146 RVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNS 205 + K + G IVNI++ +G G QV+ + KA + T+ LA E P+N+ VN+ Sbjct: 125 QNSLRKMIKQRWGRIVNISSVVGFTGNVGQVNYSTTKAGLIGFTKSLAKELAPRNVLVNA 184 Query: 206 LAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVL 265 +APG I + PL R G+ E+A+ VL+L S LASY+TG V+ Sbjct: 185 VAPGFIETDMTA---VLSEEIKQKYKEQIPLGRFGSPEEVANVVLFLCSELASYITGEVI 241 Query: 266 VADGGAW 272 +GG + Sbjct: 242 HVNGGMF 248 >4JRO-A nrPDB Length = 271 Score = 282 bits (721), Expect = 1e-76, Method: Composition-based stats. Identities = 73/252 (28%), Positives = 117/252 (46%), Gaps = 3/252 (1%) Query: 22 CPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCL 81 L+ KVA +TGG GIG IA + G + P KL G Sbjct: 23 NAMTLQGKVAVVTGGSRGIGRDIAINLAKEGANIFFNYNGSPEAAEETAKLVAEHGVEVE 82 Query: 82 PLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGT 141 + +V V A QA++ FGR+DIL+N A + + + V++I+ GT Sbjct: 83 AMKANVAIAEDVDAFFKQAIERFGRVDILVNNAGITRDNLLMRMKEDEWDDVININLKGT 142 Query: 142 FNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNI 201 F ++ + + G I+N+ + +G G A Q + ++KA V +T+ A E P+ I Sbjct: 143 FLCTKAVSRTMMKQRAGKIINMASVVGLIGNAGQANYVASKAGVIGLTKTTARELAPRGI 202 Query: 202 RVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVT 261 VN++APG I+ + + + + PL G +IA++VL+LAS + Y+T Sbjct: 203 NVNAVAPGFITTDMTDK---LDEKTKEAMLAQIPLGAYGTTEDIANAVLFLASDASKYIT 259 Query: 262 GAVLVADGGAWL 273 G L DGG + Sbjct: 260 GQTLSVDGGMVM 271 >3OSU-A nrPDB Length = 246 Score = 273 bits (699), Expect = 5e-74, Method: Composition-based stats. Identities = 65/245 (26%), Positives = 106/245 (43%), Gaps = 3/245 (1%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVR 88 K A +TG GIG IA G + + A + A G + +V Sbjct: 5 KSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVA 64 Query: 89 APPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVL 148 V A + + + +FG +D+L+N A + + V+D + G FN + Sbjct: 65 DADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKEQEWDDVIDTNLKGVFNCIQKA 124 Query: 149 YEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAP 208 + R G I+N+++ +G G Q + + KA V +T+ A E + I VN++AP Sbjct: 125 TPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGITVNAVAP 184 Query: 209 GPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVAD 268 G I +T PL R G T+IA++V +LAS A Y+TG + + Sbjct: 185 GFIVSDMTD---ALSDELKEQMLTQIPLARFGQDTDIANTVAFLASDKAKYITGQTIHVN 241 Query: 269 GGAWL 273 GG ++ Sbjct: 242 GGMYM 246 >2UVD-A nrPDB Length = 246 Score = 272 bits (697), Expect = 1e-73, Method: Composition-based stats. Identities = 68/249 (27%), Positives = 110/249 (44%), Gaps = 3/249 (1%) Query: 25 LLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLS 84 +L+ KVA +TG GIG IA + G + V+ + G + + Sbjct: 1 MLKGKVALVTGASRGIGRAIAIDLAKQGANVVVNYAGNEQKANEVVDEIKKLGSDAIAVR 60 Query: 85 MDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNV 144 DV V V Q + FG++DIL+N A + + TV++ + G F Sbjct: 61 ADVANAEDVTNMVKQTVDVFGQVDILVNNAGVTKDNLLMRMKEEEWDTVINTNLKGVFLC 120 Query: 145 SRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVN 204 ++ + R G IVNI + +G G Q + +AKA V +T+ A E +NI VN Sbjct: 121 TKAVSRFMMRQRHGRIVNIASVVGVTGNPGQANYVAAKAGVIGLTKTSAKELASRNITVN 180 Query: 205 SLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAV 264 ++APG I+ + + + P + G +IA++V + AS + Y+TG Sbjct: 181 AIAPGFIATDMTD---VLDENIKAEMLKLIPAAQFGEAQDIANAVTFFASDQSKYITGQT 237 Query: 265 LVADGGAWL 273 L DGG + Sbjct: 238 LNVDGGMVM 246 >2HQ1-A nrPDB Length = 247 Score = 270 bits (691), Expect = 4e-73, Method: Composition-based stats. Identities = 70/248 (28%), Positives = 113/248 (45%), Gaps = 3/248 (1%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L+ K A +TG G+G IA G + V+ L A + A G + Sbjct: 3 LKGKTAIVTGSSRGLGKAIAWKLGNMGANIVLNGSPASTSLDATAEEFKAAGINVVVAKG 62 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 DV+ P V V A+ FGRIDIL+N A +S + V++ + + + Sbjct: 63 DVKNPEDVENMVKTAMDAFGRIDILVNNAGITRDTLMLKMSEKDWDDVLNTNLKSAYLCT 122 Query: 146 RVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNS 205 + + + + G I+NIT+ G G A Q + ++KA + T+ +A E+ + I N+ Sbjct: 123 KAVSKIMLKQKSGKIINITSIAGIIGNAGQANYAASKAGLIGFTKSIAKEFAAKGIYCNA 182 Query: 206 LAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVL 265 +APG I P + PL+R G E+A+ V +LAS ++Y+TG V+ Sbjct: 183 VAPGIIKTDMTD---VLPDKVKEMYLNNIPLKRFGTPEEVANVVGFLASDDSNYITGQVI 239 Query: 266 VADGGAWL 273 DGG + Sbjct: 240 NIDGGLVM 247 >2C07-A nrPDB Length = 285 Score = 266 bits (680), Expect = 9e-72, Method: Composition-based stats. Identities = 64/246 (26%), Positives = 116/246 (47%), Gaps = 4/246 (1%) Query: 27 RDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMD 86 +KVA +TG G GIG IA++ + H + SR+ + ++ G + D Sbjct: 43 ENKVALVTGAGRGIGREIAKMLAKSVSHVICISRTQKSCDSVVDEIKS-FGYESSGYAGD 101 Query: 87 VRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSR 146 V + +++ L E +DIL+N A + + ++ V+ + + F +++ Sbjct: 102 VSKKEEISEVINKILTEHKNVDILVNNAGITRDNLFLRMKNDEWEDVLRTNLNSLFYITQ 161 Query: 147 VLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSL 206 + ++ + G I+NI++ +G G Q + S+KA V T+ LA E +NI VN++ Sbjct: 162 PISKRMINNRYGRIINISSIVGLTGNVGQANYSSSKAGVIGFTKSLAKELASRNITVNAI 221 Query: 207 APGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLV 266 APG IS + + ++ P R+G E+A+ +L+S + Y+ G V V Sbjct: 222 APGFISSDMTDKI---SEQIKKNIISNIPAGRMGTPEEVANLACFLSSDKSGYINGRVFV 278 Query: 267 ADGGAW 272 DGG Sbjct: 279 IDGGLS 284 >3WOH-A nrPDB Length = 251 Score = 264 bits (674), Expect = 5e-71, Method: Composition-based stats. Identities = 73/255 (28%), Positives = 111/255 (43%), Gaps = 5/255 (1%) Query: 19 HLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGR 78 + P L KVA +TGG G+G +A R G I S + G Sbjct: 2 SMTGPGALSGKVALVTGGSRGLGRAMALRLARDGAAVAIVYVSDDSSAKETQGEIERLGG 61 Query: 79 RCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDT 138 DV V V + G +DIL+N A A ++ + VM+ + Sbjct: 62 TARSYRCDVSDAEQVTRCVKAVTADLGPVDILVNNAGIIRDGLAASIKDEDYDAVMNTNL 121 Query: 139 SGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGP 198 G F + Y F R G I+NI++ G G A Q + SAKA + +T+ +A E Sbjct: 122 KGAFLFIKACYFGFIRKRSGSIINISSVSGVFGSAGQANYASAKAGLIGLTKSIAKELAE 181 Query: 199 QNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLAS 258 +N+R N++APG I+ + S ++ P++R G E+A V +LA +S Sbjct: 182 RNVRCNAVAPGLIATDMTQDLVDD-----SKRLDPVPMRRFGRPDEVAGLVAFLAGDESS 236 Query: 259 YVTGAVLVADGGAWL 273 Y+TG V+ DGG + Sbjct: 237 YITGQVVCVDGGMAM 251 >3RSH-A nrPDB Length = 251 Score = 263 bits (673), Expect = 6e-71, Method: Composition-based stats. Identities = 72/255 (28%), Positives = 123/255 (48%), Gaps = 7/255 (2%) Query: 19 HLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGR 78 + L KVA +TG GIG IAE+ G + + S A+ ++ G Sbjct: 3 AMSQFMNLEGKVALVTGASRGIGKAIAELLAERGAKVIGTATSESG----AQAISDYLGD 58 Query: 79 RCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDT 138 ++++V P ++ A + EFG +DIL+N A + + +M+ + Sbjct: 59 NGKGMALNVTNPESIEAVLKAITDEFGGVDILVNNAGITRDNLLMRMKEEEWSDIMETNL 118 Query: 139 SGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGP 198 + F +S+ + + G I+N+ + +G G A Q + +AKA V T+ +A E Sbjct: 119 TSIFRLSKAVLRGMMKKRQGRIINVGSVVGTMGNAGQANYAAAKAGVIGFTKSMAREVAS 178 Query: 199 QNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLAS 258 + + VN++APG I T+ + L Q + + P RLG+ EIA +V +LASP A+ Sbjct: 179 RGVTVNTVAPGFIE-TDMTKALNDEQ--RTATLAQVPAGRLGDPREIASAVAFLASPEAA 235 Query: 259 YVTGAVLVADGGAWL 273 Y+TG L +GG ++ Sbjct: 236 YITGETLHVNGGMYM 250 >1YXM-A nrPDB Length = 303 Score = 263 bits (673), Expect = 6e-71, Method: Composition-based stats. Identities = 91/263 (34%), Positives = 138/263 (52%), Gaps = 6/263 (2%) Query: 16 AYRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGA 75 R P LL+ +VA +TGG +GIG I + + G + VIASR L R+ +AA +L Sbjct: 6 KGRSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQAN 65 Query: 76 T----GRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFK 131 R +P+ ++R V V L FG+I+ L+N G FL PA +S + Sbjct: 66 LPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWH 125 Query: 132 TVMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRH 191 V++ + +GTF + + +Y + ++HGG IVNI G L VH+G+A+A V +T+ Sbjct: 126 AVLETNLTGTFYMCKAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKS 184 Query: 192 LAVEWGPQNIRVNSLAPGPISGTEGLRRLGGP-QASLSTKVTASPLQRLGNKTEIAHSVL 250 LA+EW IR+N +APG I + G Q+ P +R+G E++ V Sbjct: 185 LALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVC 244 Query: 251 YLASPLASYVTGAVLVADGGAWL 273 +L SP AS++TG + DGG L Sbjct: 245 FLLSPAASFITGQSVDVDGGRSL 267 >3EMK-A nrPDB Length = 246 Score = 262 bits (671), Expect = 1e-70, Method: Composition-based stats. Identities = 69/248 (27%), Positives = 114/248 (45%), Gaps = 7/248 (2%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L + A +TG G+G IA G + ++ A +L G R Sbjct: 5 LTGRKALVTGATGGLGEAIARALHAQGAIVGLHGTREEKLKELAAEL----GERIFVFPA 60 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 ++ AV A +A +E G +DIL+N A +S + V+ ++ + FN++ Sbjct: 61 NLSDREAVKALGQKAEEEMGGVDILVNNAGITRDGLFVRMSDEDWDAVLTVNLTSVFNLT 120 Query: 146 RVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNS 205 R L R G I+NIT+ +G G Q + ++KA + ++ LA E +N+ VN Sbjct: 121 RELTHPMMRRRNGRIINITSIVGVTGNPGQANYCASKAGLIGFSKSLAQEIASRNVTVNC 180 Query: 206 LAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVL 265 +APG I + + + P++R+G +IA +V+YLAS A+YVTG L Sbjct: 181 IAPGFIESAMTGK---LNEKQKDAIMGNIPMKRMGVGADIAAAVVYLASDEAAYVTGQTL 237 Query: 266 VADGGAWL 273 +GG + Sbjct: 238 HVNGGMAM 245 >5ITV-A nrPDB Length = 255 Score = 258 bits (660), Expect = 2e-69, Method: Composition-based stats. Identities = 73/252 (28%), Positives = 116/252 (46%), Gaps = 8/252 (3%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L DK ITGG SGIG+ + F+ + V+A + RK R + Sbjct: 5 LTDKTVLITGGASGIGYAAVQAFLGQQANVVVADIDEAQGEAMVRK---ENNDRLHFVQT 61 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 D+ A AV+ A+ FG +D+LIN A + P + + + V+ ++ +G F +S Sbjct: 62 DITDEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELSDWNKVLQVNLTGMFLMS 121 Query: 146 RVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNS 205 + + G I+N + G ++K V +T+ +AV++ IRVN Sbjct: 122 KHALKHMLAAGKGNIINTCSVGGLVAWPDIPAYNASKGGVLQLTKSMAVDYAKHQIRVNC 181 Query: 206 LAPGPISGTEGLRRL-----GGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYV 260 + PG I + G + K +PL RLG EIA+ +L+LAS L+SY+ Sbjct: 182 VCPGIIDTPLNEKSFLENNEGTLEEIKKEKAKVNPLLRLGKPEEIANVMLFLASDLSSYM 241 Query: 261 TGAVLVADGGAW 272 TG+ + ADGG Sbjct: 242 TGSAITADGGYT 253 >3FTP-A nrPDB Length = 270 Score = 256 bits (655), Expect = 6e-69, Method: Composition-based stats. Identities = 86/250 (34%), Positives = 123/250 (49%), Gaps = 4/250 (1%) Query: 25 LLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLS 84 L +VA +TG GIG IA R G + + + A G Sbjct: 25 TLDKQVAIVTGASRGIGRAIALELARRGAMVIGTATTEAGAEGIGAAFKQA-GLEGRGAV 83 Query: 85 MDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNV 144 ++V AV A V+ LKEFG +++L+N A A + + + V+D + F + Sbjct: 84 LNVNDATAVDALVESTLKEFGALNVLVNNAGITQDQLAMRMKDDEWDAVIDTNLKAVFRL 143 Query: 145 SRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVN 204 SR + + GG IVNIT+ +G+ G QV+ +AKA V MTR LA E G + I VN Sbjct: 144 SRAVLRPMMKARGGRIVNITSVVGSAGNPGQVNYAAAKAGVAGMTRALAREIGSRGITVN 203 Query: 205 SLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAV 264 +APG I G PQ + T PL RLG+ +IAH+V +LASP A Y+TG Sbjct: 204 CVAPGFIDTDM---TKGLPQEQQTALKTQIPLGRLGSPEDIAHAVAFLASPQAGYITGTT 260 Query: 265 LVADGGAWLT 274 L +GG +++ Sbjct: 261 LHVNGGMFMS 270 >4DMM-A nrPDB Length = 269 Score = 256 bits (655), Expect = 7e-69, Method: Composition-based stats. Identities = 70/261 (26%), Positives = 115/261 (44%), Gaps = 8/261 (3%) Query: 14 LPAYRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLA 73 +P H+ L D++A +TG GIG IA G + S Sbjct: 15 VPRGSHM-TALPLTDRIALVTGASRGIGRAIALELAAAGAKVAVNYASSAGAADEVVAAI 73 Query: 74 GATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTV 133 A G + DV V A ++ +GR+D+L+N A + + +++V Sbjct: 74 AAAGGEAFAVKADVSQESEVEALFAAVIERWGRLDVLVNNAGITRDTLLLRMKRDDWQSV 133 Query: 134 MDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLA 193 +D++ G F SR + + G I+NI + +G G Q + +AKA V +T+ +A Sbjct: 134 LDLNLGGVFLCSRAAAKIMLKQRSGRIINIASVVGEMGNPGQANYSAAKAGVIGLTKTVA 193 Query: 194 VEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLA 253 E + I VN++APG I+ + + + PL R G E+A V +LA Sbjct: 194 KELASRGITVNAVAPGFIATDMTS------ELAAEKLLEVIPLGRYGEAAEVAGVVRFLA 247 Query: 254 SP-LASYVTGAVLVADGGAWL 273 + A+Y+TG V+ DGG + Sbjct: 248 ADPAAAYITGQVINIDGGLVM 268 >3LYL-A nrPDB Length = 247 Score = 254 bits (650), Expect = 3e-68, Method: Composition-based stats. Identities = 66/250 (26%), Positives = 112/250 (44%), Gaps = 4/250 (1%) Query: 24 DLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPL 83 L +KVA +TG GIGF +A G V + S + G + L Sbjct: 1 MSLNEKVALVTGASRGIGFEVAHALASKGATVVGTATSQASAEKFENSMKEK-GFKARGL 59 Query: 84 SMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFN 143 +++ ++ + E IDIL+N A +S + +++V++ + S F Sbjct: 60 VLNISDIESIQNFFAEIKAENLAIDILVNNAGITRDNLMMRMSEDEWQSVINTNLSSIFR 119 Query: 144 VSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRV 203 +S+ + G I++I + +G+ G Q + +AKA V ++ LA E +NI V Sbjct: 120 MSKECVRGMMKKRWGRIISIGSVVGSAGNPGQTNYCAAKAGVIGFSKSLAYEVASRNITV 179 Query: 204 NSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGA 263 N +APG I+ + S T P ++G +IA +V +LAS A Y+TG Sbjct: 180 NVVAPGFIATDMTDK---LTDEQKSFIATKIPSGQIGEPKDIAAAVAFLASEEAKYITGQ 236 Query: 264 VLVADGGAWL 273 L +GG ++ Sbjct: 237 TLHVNGGMYM 246 >4BO1-A nrPDB Length = 269 Score = 254 bits (650), Expect = 3e-68, Method: Composition-based stats. Identities = 75/255 (29%), Positives = 120/255 (47%), Gaps = 4/255 (1%) Query: 20 LFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRR 79 F L+ KVA +TG GIG IA R G VI + + + A G Sbjct: 19 YFQSMSLQGKVALVTGASRGIGQAIALELGRLGA-VVIGTATSASGAEKIAETLKANGVE 77 Query: 80 CLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTS 139 L +DV + +V A ++ + G+ I++N A + + + V++ + + Sbjct: 78 GAGLVLDVSSDESVAATLEHIQQHLGQPLIVVNNAGITRDNLLVRMKDDEWFDVVNTNLN 137 Query: 140 GTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQ 199 + +S+ + + G I+NI + +G G A Q + +AKA ++ TR LA E G + Sbjct: 138 SLYRLSKAVLRGMTKARWGRIINIGSVVGAMGNAGQTNYAAAKAGLEGFTRALAREVGSR 197 Query: 200 NIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASY 259 I VN++APG I P+A + PL RLG EIA V +LAS A+Y Sbjct: 198 AITVNAVAPGFIDTDMTRE---LPEAQREALLGQIPLGRLGQAEEIAKVVGFLASDGAAY 254 Query: 260 VTGAVLVADGGAWLT 274 VTGA + +GG +++ Sbjct: 255 VTGATVPVNGGMYMS 269 >1Q7C-A nrPDB Length = 244 Score = 252 bits (645), Expect = 1e-67, Method: Composition-based stats. Identities = 69/248 (27%), Positives = 117/248 (47%), Gaps = 7/248 (2%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 K+A +TG GIG IAE G + + S A+ ++ G L + Sbjct: 3 FEGKIALVTGASRGIGRAIAETLAARGAKVIGTATSENG----AQAISDYLGANGKGLML 58 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 +V P ++ + +++ EFG +DIL+N A + + +++ + S F +S Sbjct: 59 NVTDPASIESVLEKIRAEFGEVDILVNNAGITRDNLLMRMKDEEWNDIIETNLSSVFRLS 118 Query: 146 RVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNS 205 + + + G I+ I + +G G Q + +AKA + ++ LA E + I VN Sbjct: 119 KAVMRAMMKKRHGRIITIGSVVGTMGNGGQANFAAAKAGLIGFSKSLAREVASRGITVNV 178 Query: 206 LAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVL 265 +APG I T+ R L Q + + P RLG EIA++V +LAS A+Y+TG L Sbjct: 179 VAPGFIE-TDMTRALSDDQ--RAGILAQVPAGRLGGAQEIANAVAFLASDEAAYITGETL 235 Query: 266 VADGGAWL 273 +GG ++ Sbjct: 236 HVNGGMYM 243 >1GEE-A nrPDB Length = 261 Score = 252 bits (644), Expect = 1e-67, Method: Composition-based stats. Identities = 75/249 (30%), Positives = 119/249 (47%), Gaps = 2/249 (0%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L KV ITG +G+G +A F V+ RS + + G + + Sbjct: 5 LEGKVVVITGSSTGLGKSMAIRFATEKAKVVVNYRSKEDEANSVLEEIKKVGGEAIAVKG 64 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 DV V+ V A+KEFG++D++IN A + +S + + V+D + +G F S Sbjct: 65 DVTVESDVINLVQSAIKEFGKLDVMINNAGLENPVSSHEMSLSDWNKVIDTNLTGAFLGS 124 Query: 146 RVLYEKFFRDH-GGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVN 204 R + F + G ++N+++ L VH ++K + MT LA+E+ P+ IRVN Sbjct: 125 REAIKYFVENDIKGTVINMSSVHEKIPWPLFVHYAASKGGMKLMTETLALEYAPKGIRVN 184 Query: 205 SLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAV 264 ++ PG I+ + P+ + + P+ +G EIA +LAS ASYVTG Sbjct: 185 NIGPGAINTPINAEKFADPEQRADVE-SMIPMGYIGEPEEIAAVAAWLASSEASYVTGIT 243 Query: 265 LVADGGAWL 273 L ADGG L Sbjct: 244 LFADGGMTL 252 >5CDY-A nrPDB Length = 244 Score = 252 bits (643), Expect = 2e-67, Method: Composition-based stats. Identities = 72/250 (28%), Positives = 119/250 (47%), Gaps = 7/250 (2%) Query: 24 DLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPL 83 K+A +TG GIG IAE+ + G + + S A ++ G L Sbjct: 1 MSFEGKIALVTGASRGIGRAIAELLVERGACVIGTATSEKG----AEAISAYLGENGKGL 56 Query: 84 SMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFN 143 ++V P ++ + EFG +DIL+N A + + ++ ++D + + F Sbjct: 57 MLNVVDPTSIDTVLATIRAEFGEVDILVNNAGITRDNLLMRMKDDEWQDIIDTNLTSVFR 116 Query: 144 VSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRV 203 +S+ + + G I+ I + +G G A QV+ +AKA V ++ LA E + I V Sbjct: 117 LSKAVMRAMMKKRFGRIITIGSVVGTMGNAGQVNYAAAKAGVIGFSKSLAREVASRGITV 176 Query: 204 NSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGA 263 N +APG I T+ R L Q + + P RLG+ EIA +V +LAS ASY++G Sbjct: 177 NVVAPGFIE-TDMTRTLTDDQ--RAGILAQVPANRLGDAKEIASAVAFLASDEASYISGE 233 Query: 264 VLVADGGAWL 273 L +GG ++ Sbjct: 234 TLHVNGGMYM 243 >3AUT-A nrPDB Length = 269 Score = 251 bits (642), Expect = 2e-67, Method: Composition-based stats. Identities = 78/253 (30%), Positives = 125/253 (49%), Gaps = 3/253 (1%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L+DKV ITGG +G+G +A F + VI + A+K G + + + Sbjct: 13 LKDKVVVITGGSTGLGRAMAVRFGQEEAKVVINYYNNEEEALDAKKEVEEAGGQAIIVQG 72 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 DV V+ V A+KEFG +D++IN A P+ LS + + V+D + +G F S Sbjct: 73 DVTKEEDVVNLVQTAIKEFGTLDVMINNAGVENPVPSHELSLDNWNKVIDTNLTGAFLGS 132 Query: 146 RVLYEKFFRDH-GGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVN 204 R + F + G ++N+++ L VH ++K + MT LA+E+ P+ IRVN Sbjct: 133 REAIKYFVENDIKGNVINMSSVHEMIPWPLFVHYAASKGGMKLMTETLALEYAPKGIRVN 192 Query: 205 SLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAV 264 ++ PG ++ + P + + P+ +G E+A +LAS ASYVTG Sbjct: 193 NIGPGAMNTPINAEKFADPVQRADVE-SMIPMGYIGKPEEVAAVAAFLASSQASYVTGIT 251 Query: 265 LVADGGAWLTFPN 277 L ADGG +P+ Sbjct: 252 LFADGGMT-KYPS 263 >3F9I-A nrPDB Length = 249 Score = 251 bits (641), Expect = 3e-67, Method: Composition-based stats. Identities = 63/248 (25%), Positives = 108/248 (43%), Gaps = 11/248 (4%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L K + ITG SGIG IA + + G +I+ + ++ + L Sbjct: 12 LTGKTSLITGASSGIGSAIARLLHKLGSKVIISGSNEEKLKSLGNALKDNYTIEV----C 67 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 ++ + + +DIL+ A A + F V+DI+ F ++ Sbjct: 68 NLANKEECSNLISKT----SNLDILVCNAGITSDTLAIRMKDQDFDKVIDINLKANFILN 123 Query: 146 RVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNS 205 R +K + G I+NI++ +G G Q + ++KA + MT+ L+ E + I VN+ Sbjct: 124 REAIKKMIQKRYGRIINISSIVGIAGNPGQANYCASKAGLIGMTKSLSYEVATRGITVNA 183 Query: 206 LAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVL 265 +APG I + + V PL G ++A++V +LAS ASY+TG L Sbjct: 184 VAPGFIKSDMTDK---LNEKQREAIVQKIPLGTYGIPEDVAYAVAFLASNNASYITGQTL 240 Query: 266 VADGGAWL 273 +GG + Sbjct: 241 HVNGGMLM 248 >4M8S-A nrPDB Length = 248 Score = 250 bits (639), Expect = 5e-67, Method: Composition-based stats. Identities = 72/248 (29%), Positives = 115/248 (46%), Gaps = 6/248 (2%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L K+A +TG GIG IA+ G + + S + +LA G + Sbjct: 6 LSGKIALVTGASRGIGAAIADTLAAAGAKVIGTATSESGAAAISERLAQWGGE---GRVL 62 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 + P V + K FG++DIL+N A + + +M ++ F S Sbjct: 63 NSAEPETVENLIADIEKTFGKLDILVNNAGITRDNLLMRMKEEEWDDIMQVNLKSVFRAS 122 Query: 146 RVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNS 205 + + + G I+NIT+ +G G A Q + +AKA + ++ +A E G + I VN Sbjct: 123 KAVLRGMMKQRAGRIINITSVVGVMGNAGQTNYAAAKAGLIGFSKSMAREVGSRGITVNC 182 Query: 206 LAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVL 265 +APG I T+ R L P+ + T + L R G+ +IA +VL+LAS A Y+TG L Sbjct: 183 VAPGFID-TDMTRAL--PEETRQTFTAQTALGRFGDAQDIADAVLFLASDQAKYITGQTL 239 Query: 266 VADGGAWL 273 +GG + Sbjct: 240 HVNGGMLM 247 >3GRP-A nrPDB Length = 266 Score = 249 bits (637), Expect = 7e-67, Method: Composition-based stats. Identities = 66/250 (26%), Positives = 109/250 (43%), Gaps = 7/250 (2%) Query: 24 DLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPL 83 L + A +TG GIG IA F G + ++ A L G+ Sbjct: 23 FKLTGRKALVTGATGGIGEAIARCFHAQGAIVGLHGTREDKLKEIAADL----GKDVFVF 78 Query: 84 SMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFN 143 S ++ ++ + A +E IDIL+N A + + V+ ++ + Sbjct: 79 SANLSDRKSIKQLAEVAEREMEGIDILVNNAGITRDGLFVRMQDQDWDDVLAVNLTAAST 138 Query: 144 VSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRV 203 ++R L R G I+NIT+ +G G Q + +AKA + ++ LA E +NI V Sbjct: 139 LTRELIHSMMRRRYGRIINITSIVGVVGNPGQTNYCAAKAGLIGFSKALAQEIASRNITV 198 Query: 204 NSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGA 263 N +APG I + + + P++R+G EIA + +YLAS A+Y+TG Sbjct: 199 NCIAPGFIKSAMTDK---LNEKQKEAIMAMIPMKRMGIGEEIAFATVYLASDEAAYLTGQ 255 Query: 264 VLVADGGAWL 273 L +GG + Sbjct: 256 TLHINGGMAM 265 >3O4R-A nrPDB Length = 261 Score = 248 bits (633), Expect = 2e-66, Method: Composition-based stats. Identities = 74/252 (29%), Positives = 113/252 (44%), Gaps = 3/252 (1%) Query: 20 LFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRR 79 + D L +KVA +T GIGF IA + G H V++SR V A L G G Sbjct: 7 MTRRDPLANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGE-GLS 65 Query: 80 CLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGN-FLCPAGALSFNAFKTVMDIDT 138 V V A+K G IDIL++ AA N F ++ + +DI+ Sbjct: 66 VTGTVCHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINV 125 Query: 139 SGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGP 198 +++ + + + GG +V +++ +K A+ +T+ LA+E P Sbjct: 126 KAPALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAP 185 Query: 199 QNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLAS 258 +NIRVN LAPG I + R L + + ++RLG + A V +L S AS Sbjct: 186 RNIRVNCLAPGLIKTSFS-RMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSEDAS 244 Query: 259 YVTGAVLVADGG 270 Y+TG +V GG Sbjct: 245 YITGETVVVGGG 256 >4IIN-A nrPDB Length = 271 Score = 247 bits (630), Expect = 6e-66, Method: Composition-based stats. Identities = 67/256 (26%), Positives = 109/256 (42%), Gaps = 5/256 (1%) Query: 20 LFCPDLLR--DKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATG 77 F + ++ K ITG GIG IA+ G I RS V A + G Sbjct: 19 YFQSNAMQFTGKNVLITGASKGIGAEIAKTLASMGLKVWINYRSNAEVADALKNELEEKG 78 Query: 78 RRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDID 137 + + D + + A+ ++ G + L+N A A + F V+D + Sbjct: 79 YKAAVIKFDAASESDFIEAIQTIVQSDGGLSYLVNNAGVVRDKLAIKMKTEDFHHVIDNN 138 Query: 138 TSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWG 197 + F R + + G +VN+ + +G RG Q + ++K + AM++ A E Sbjct: 139 LTSAFIGCREALKVMSKSRFGSVVNVASIIGERGNMGQTNYSASKGGMIAMSKSFAYEGA 198 Query: 198 PQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLA 257 +NIR NS+ PG I + V PL RLG+ E+A +V +L S + Sbjct: 199 LRNIRFNSVTPGFIETDMNA---NLKDELKADYVKNIPLNRLGSAKEVAEAVAFLLSDHS 255 Query: 258 SYVTGAVLVADGGAWL 273 SY+TG L +GG ++ Sbjct: 256 SYITGETLKVNGGLYM 271 >2PH3-A nrPDB Length = 245 Score = 247 bits (630), Expect = 6e-66, Method: Composition-based stats. Identities = 68/245 (27%), Positives = 102/245 (41%), Gaps = 4/245 (1%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPL-SMDV 87 + A ITG GIG IA G I + A G + + ++ Sbjct: 2 RKALITGASRGIGRAIALRLAEDGFALAIHYGQNREKAEEVAEEARRRGSPLVAVLGANL 61 Query: 88 RAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRV 147 A A V QA + G +D L+N A + ++ V++ + S F +R Sbjct: 62 LEAEAATALVHQAAEVLGGLDTLVNNAGITRDTLLVRMKDEDWEAVLEANLSAVFRTTRE 121 Query: 148 LYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLA 207 + + G IVNIT+ +G G Q + ++KA + TR +A E+ + I VN++A Sbjct: 122 AVKLMMKARFGRIVNITSVVGILGNPGQANYVASKAGLIGFTRAVAKEYAQRGITVNAVA 181 Query: 208 PGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVA 267 PG I R PQ + P R G E+A +V +L S A Y+TG L Sbjct: 182 PGFIETEMTER---LPQEVKEAYLKQIPAGRFGRPEEVAEAVAFLVSEKAGYITGQTLCV 238 Query: 268 DGGAW 272 DGG Sbjct: 239 DGGLT 243 >6NRP-A nrPDB Length = 263 Score = 245 bits (627), Expect = 1e-65, Method: Composition-based stats. Identities = 67/255 (26%), Positives = 105/255 (41%), Gaps = 9/255 (3%) Query: 18 RHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATG 77 +L+ + + +TG GIG IA + G + +RS + A G Sbjct: 16 ENLYFQSM--TRRILVTGSSRGIGKAIALQLAKAGFDVTVHARSRQAEAEQVVQEIQALG 73 Query: 78 RRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDID 137 + L DV V ++Q +++ G ++ A AL+ + V+ Sbjct: 74 QNSHYLMFDVNERQTVQQILEQDVEQHGGFYGVVLNAGLTHDGAFPALTDQDWDEVISTS 133 Query: 138 TSGTFNVSRVLYEKFFR-DHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEW 196 G +NV + L GG IV +++ G G QV+ +AKA + T+ LA+E Sbjct: 134 LDGFYNVLKPLIMPMIHLRKGGRIVTLSSVSGIMGNRGQVNYSAAKAGLIGATKALALEL 193 Query: 197 GPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPL 256 + I VN +APG I + PLQR+G E+A V +L S Sbjct: 194 AKRKITVNCVAPGLIETEMVT------DEVKEHALKMIPLQRMGQVDEVASVVKFLCSDE 247 Query: 257 ASYVTGAVLVADGGA 271 ASYVT V+ +GG Sbjct: 248 ASYVTRQVISVNGGL 262 >2CDH-G nrPDB Length = 244 Score = 245 bits (626), Expect = 2e-65, Method: Composition-based stats. Identities = 65/242 (26%), Positives = 106/242 (43%), Gaps = 4/242 (1%) Query: 30 VAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRA 89 V +TG GIG IA + GC ++ + K A G + + DV Sbjct: 3 VVVVTGASRGIGKAIALSLGKAGCKVLVNYARSAKAAEEVSKQIEAYGGQAITFGGDVSK 62 Query: 90 PPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVLY 149 V A + A+ +G ID+++N A + + + V+D++ +G F ++ Sbjct: 63 EADVEAMMKTAIDAWGTIDVVVNNAGITRDTLLIRMKKSQWDEVIDLNLTGVFLCTQAAT 122 Query: 150 EKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPG 209 + + G I+NI + +G G Q + +AKA V ++ A E +NI VN + PG Sbjct: 123 KIMMKKRKGRIINIASVVGLIGNIGQANYAAAKAGVIGFSKTAAREGASRNINVNVVCPG 182 Query: 210 PISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLA-SPLASYVTGAVLVAD 268 I+ + + + + PL R G +A V +LA SP ASY+TG D Sbjct: 183 FIASDMTAKLGEDMEKKI---LGTIPLGRTGQPENVAGLVEFLALSPAASYITGQAFTID 239 Query: 269 GG 270 GG Sbjct: 240 GG 241 >4K6F-A nrPDB Length = 255 Score = 244 bits (624), Expect = 2e-65, Method: Composition-based stats. Identities = 63/249 (25%), Positives = 112/249 (44%), Gaps = 4/249 (1%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 + ++A +TGG G+G ++ G V+ A GR + Sbjct: 9 MTKRIAVVTGGMGGLGEAVSIRLNDAGHRVVVTYSPNNTGADRWLTEMHAAGREFHAYPV 68 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 DV + +++ +++ G +DIL+N A L + V+ + FN++ Sbjct: 69 DVADHDSCQQCIEKIVRDVGPVDILVNNAGITRDMTLRKLDKVNWDAVIRTNLDSVFNMT 128 Query: 146 RVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNS 205 + + + G IVNI++ G++G Q + +AKA + T+ LA+E + + VN+ Sbjct: 129 KPVCDGMVERGWGRIVNISSVNGSKGSVGQTNYAAAKAGMHGFTKSLALEIARKGVTVNT 188 Query: 206 LAPGPISGTEGLRRLGGPQASLSTKVT-ASPLQRLGNKTEIAHSVLYLASPLASYVTGAV 264 ++PG ++ PQ L TK+ P RLG E+A V YL S A +VTG+ Sbjct: 189 VSPGYLATKMVTAI---PQDILDTKILPQIPAGRLGKPEEVAALVAYLCSEEAGFVTGSN 245 Query: 265 LVADGGAWL 273 + +GG + Sbjct: 246 IAINGGQHM 254 >4RZH-A nrPDB Length = 247 Score = 244 bits (623), Expect = 4e-65, Method: Composition-based stats. Identities = 65/249 (26%), Positives = 107/249 (42%), Gaps = 7/249 (2%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L +VA +TG GIG A G V+ A A G + + Sbjct: 4 LTAQVALVTGASRGIGKATALALAATGMKVVVNYAQSSTAADAVVAEIIANGGEAIAVQA 63 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 +V V + L +F RID+L+N A + ++ V+D++ +G F + Sbjct: 64 NVANADEVDQLIKTTLDKFSRIDVLVNNAGITRDTLLLRMKLEDWQAVIDLNLTGVFLCT 123 Query: 146 RVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNS 205 + + + + G I+NIT+ G G Q + +AKA V T+ +A E + + VN+ Sbjct: 124 KAVSKLMLKQKSGRIINITSVAGMMGNPGQANYSAAKAGVIGFTKTVAKELASRGVTVNA 183 Query: 206 LAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASP-LASYVTGAV 264 +APG I+ P + PL R G E+A ++ +LA+ A+Y+TG Sbjct: 184 VAPGFIATDMTENLNAEP------ILQFIPLARYGQPEEVAGTIRFLATDPAAAYITGQT 237 Query: 265 LVADGGAWL 273 DGG + Sbjct: 238 FNVDGGMVM 246 >2ZAT-A nrPDB Length = 260 Score = 242 bits (617), Expect = 2e-64, Method: Composition-based stats. Identities = 69/247 (27%), Positives = 110/247 (44%), Gaps = 3/247 (1%) Query: 25 LLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLS 84 L +KVA +T GIG IA + G H V++SR V L G G Sbjct: 11 PLENKVALVTASTDGIGLAIARRLAQDGAHVVVSSRKQENVDRTVATLQGE-GLSVTGTV 69 Query: 85 MDVRAPPAVMAAVDQALKEFGRIDILINCAAGN-FLCPAGALSFNAFKTVMDIDTSGTFN 143 V V A+ G +DIL++ AA N F + + ++ ++ T Sbjct: 70 CHVGKAEDRERLVAMAVNLHGGVDILVSNAAVNPFFGNIIDATEEVWDKILHVNVKATVL 129 Query: 144 VSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRV 203 +++ + + + GG ++ +++ +K A+ +T++LAVE P+NIRV Sbjct: 130 MTKAVVPEMEKRGGGSVLIVSSVGAYHPFPNLGPYNVSKTALLGLTKNLAVELAPRNIRV 189 Query: 204 NSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGA 263 N LAPG I + L +A + ++RLGN + A V +L S ASY+TG Sbjct: 190 NCLAPGLIKTNFS-QVLWMDKARKEYMKESLRIRRLGNPEDCAGIVSFLCSEDASYITGE 248 Query: 264 VLVADGG 270 +V GG Sbjct: 249 TVVVGGG 255 >4NBV-A nrPDB Length = 246 Score = 240 bits (613), Expect = 5e-64, Method: Composition-based stats. Identities = 77/248 (31%), Positives = 113/248 (45%), Gaps = 4/248 (1%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L+ +VA ITG +GIGF A+ F G V+ RV AA +LA + Sbjct: 3 LQGRVAIITGAAAGIGFATAQRFAEDGAIVVLCDVQEARVREAAARLAATG-ATVSAYRV 61 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 DV V A V L R+DIL+N A ++ F V+D++ G FN + Sbjct: 62 DVTRRDEVDAMVAAVLAAHQRVDILVNNAGITKDARLAKMTEAQFDAVIDVNLKGVFNCA 121 Query: 146 RVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNS 205 + + GVI+N ++ +G G Q + ++K V T+ A E GP+ +RVN+ Sbjct: 122 QAVAGLMTEQGKGVILNASSVVGLYGNFGQTNYAASKFGVIGFTKTWARELGPKGVRVNA 181 Query: 206 LAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVL 265 + PG ++ P L ++ L+RL EIA +LAS ASYV G + Sbjct: 182 VCPGFVNTEILQTV---PDKVLDGMTSSCWLRRLAEPAEIASIYAFLASDDASYVNGVAI 238 Query: 266 VADGGAWL 273 A GG L Sbjct: 239 EASGGMSL 246 >2EW8-A nrPDB Length = 249 Score = 240 bits (613), Expect = 5e-64, Method: Composition-based stats. Identities = 86/248 (34%), Positives = 114/248 (45%), Gaps = 8/248 (3%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIAS-RSLPRVLTAARKLAGATGRRCLPLS 84 L+DK+A ITGG +GIG IAE F G IA P A R L GRR L + Sbjct: 5 LKDKLAVITGGANGIGRAIAERFAVEGADIAIADLVPAPEAEAAIRNL----GRRVLTVK 60 Query: 85 MDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNV 144 DV P V A Q + FGR DIL+N A L P L+F +K +I+ F + Sbjct: 61 CDVSQPGDVEAFGKQVISTFGRCDILVNNAGIYPLIPFDELTFEQWKKTFEINVDSGFLM 120 Query: 145 SRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVN 204 ++ R+ G I+N+T+T H S KAA TR LA + G I VN Sbjct: 121 AKAFVPGMKRNGWGRIINLTSTTYWLKIEAYTHYISTKAANIGFTRALASDLGKDGITVN 180 Query: 205 SLAPGPISG-TEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGA 263 ++AP + T L L + A P RL ++ + +LAS AS++TG Sbjct: 181 AIAPSLVRTATTEASALSAMFDVLPNMLQAIP--RLQVPLDLTGAAAFLASDDASFITGQ 238 Query: 264 VLVADGGA 271 L DGG Sbjct: 239 TLAVDGGM 246 >3OEC-A nrPDB Length = 317 Score = 240 bits (613), Expect = 6e-64, Method: Composition-based stats. Identities = 76/274 (27%), Positives = 122/274 (44%), Gaps = 26/274 (9%) Query: 24 DLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIAS-----------RSLPRVLTAARKL 72 + L+ KVAFITG G G A + G V + P L +L Sbjct: 42 NRLQGKVAFITGAARGQGRTHAVRLAQDGADIVAIDLCRQQPNLDYAQGSPEELKETVRL 101 Query: 73 AGATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKT 132 GRR + DVR ++ A VD+AL EFG IDIL++ + +L+ + Sbjct: 102 VEEQGRRIIARQADVRDLASLQAVVDEALAEFGHIDILVSNVGISNQGEVVSLTDQQWSD 161 Query: 133 VMDIDTSGTFNVSRVLYEKFF-RDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRH 191 ++ + G ++ R + R GG ++ +++T+G RG Q H ++K V + Sbjct: 162 ILQTNLIGAWHACRAVLPSMIERGQGGSVIFVSSTVGLRGAPGQSHYAASKHGVQGLMLS 221 Query: 192 LAVEWGPQNIRVNSLAPGPISGTEGLR----RLGGPQASLSTKVTAS---------PLQR 238 LA E G NIRVNS+ PG ++ L ++ P T+ A+ P+ Sbjct: 222 LANEVGRHNIRVNSVNPGAVNTEMALNEKLLKMFLPHLENPTREDAAELFSQLTLLPIP- 280 Query: 239 LGNKTEIAHSVLYLASPLASYVTGAVLVADGGAW 272 +++++V +LAS A Y+ GA + DGG Sbjct: 281 WVEPEDVSNAVAWLASDEARYIHGAAIPVDGGQL 314 >3EZL-A nrPDB Length = 256 Score = 239 bits (609), Expect = 1e-63, Method: Composition-based stats. Identities = 66/251 (26%), Positives = 115/251 (45%), Gaps = 3/251 (1%) Query: 24 DLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPL 83 ++ ++A++TGG GIG I + + G V + A G Sbjct: 9 MVMSQRIAYVTGGMGGIGTSICQRLHKDGFRVVAGCGPNSPRRVKWLEDQKALGFDFYAS 68 Query: 84 SMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFN 143 +V + A D+ E G ID+L+N A ++ ++ V+D + + FN Sbjct: 69 EGNVGDWDSTKQAFDKVKAEVGEIDVLVNNAGITRDVVFRKMTREDWQAVIDTNLTSLFN 128 Query: 144 VSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRV 203 V++ + + G I+NI++ G +GQ Q + +AKA + T LA E + + V Sbjct: 129 VTKQVIDGMVERGWGRIINISSVNGQKGQFGQTNYSTAKAGIHGFTMSLAQEVATKGVTV 188 Query: 204 NSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGA 263 N+++PG I GT+ ++ + L V P++RLG+ EI V +LAS + + TGA Sbjct: 189 NTVSPGYI-GTDMVKAI--RPDVLEKIVATIPVRRLGSPDEIGSIVAWLASEESGFSTGA 245 Query: 264 VLVADGGAWLT 274 +GG + Sbjct: 246 DFSLNGGLHMG 256 >5VT6-A nrPDB Length = 269 Score = 238 bits (608), Expect = 2e-63, Method: Composition-based stats. Identities = 72/254 (28%), Positives = 116/254 (45%), Gaps = 5/254 (1%) Query: 23 PDLLRDK-VAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCL 81 P ++ K VAF+TGG G+G I+ G ++ ++ GR Sbjct: 19 PGSMQAKRVAFVTGGMGGLGAAISRRLHDAGMAVAVSHSERNDHVSTWLMHERDAGRDFK 78 Query: 82 PLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGT 141 ++DV + ++ L +FG++D+LIN A ++ + VM D Sbjct: 79 AYAVDVADFESCERCAEKVLADFGKVDVLINNAGITRDATFMKMTKGDWDAVMRTDLDAM 138 Query: 142 FNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNI 201 FNV++ G IVNI + G+RG Q + SAKA + T+ LA+E + I Sbjct: 139 FNVTKQFIAGMVERRFGRIVNIGSVNGSRGAFGQANYASAKAGIHGFTKTLALETAKRGI 198 Query: 202 RVNSLAPGPISGTEGLRRLGGPQASLSTKVT-ASPLQRLGNKTEIAHSVLYLASPLASYV 260 VN+++PG ++ PQ L K+ P+ RLG E+A + +L S A +V Sbjct: 199 TVNTVSPGYLATAMVEAV---PQDVLEAKILPQIPVGRLGRPDEVAALIAFLCSDDAGFV 255 Query: 261 TGAVLVADGGAWLT 274 TGA L +GG ++ Sbjct: 256 TGADLAINGGMHMS 269 >2NM0-A nrPDB Length = 253 Score = 238 bits (608), Expect = 2e-63, Method: Composition-based stats. Identities = 74/246 (30%), Positives = 110/246 (44%), Gaps = 15/246 (6%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVR 88 + +TGG GIG IA F G I RS G L + D+ Sbjct: 22 RSVLVTGGNRGIGLAIARAFADAGDKVAITYRS------------GEPPEGFLAVKCDIT 69 Query: 89 APPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVL 148 V A + + G +++LI A +S F +V++ + +GTF V + Sbjct: 70 DTEQVEQAYKEIEETHGPVEVLIANAGVTKDQLLMRMSEEDFTSVVETNLTGTFRVVKRA 129 Query: 149 YEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAP 208 R G +V I++ +G G A Q + ++KA + R LA E G +NI N +AP Sbjct: 130 NRAMLRAKKGRVVLISSVVGLLGSAGQANYAASKAGLVGFARSLARELGSRNITFNVVAP 189 Query: 209 GPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVAD 268 G + T+ + L Q + V+ PL R EIA +V +LAS ASY+TGAV+ D Sbjct: 190 GFVD-TDMTKVLTDEQ--RANIVSQVPLGRYARPEEIAATVRFLASDDASYITGAVIPVD 246 Query: 269 GGAWLT 274 GG + Sbjct: 247 GGLGMG 252 >4NBT-A nrPDB Length = 240 Score = 238 bits (608), Expect = 2e-63, Method: Composition-based stats. Identities = 71/250 (28%), Positives = 111/250 (44%), Gaps = 15/250 (6%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L KVA ITGG G+G IA + G + + + + Sbjct: 4 LEGKVAVITGGAKGLGQAIALAYAEEGAKVIAGDLGD----------LTYSHPNVEGMYL 53 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 +V V + ++G+IDIL+N A ++ + V+D++ G FN++ Sbjct: 54 NVTDVTGVEKFYQSVIDKYGKIDILVNNAGITKDAMTRKMTEAQWDAVIDVNLKGVFNLT 113 Query: 146 RVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQN--IRV 203 R++ + + G I+NI++ +G G Q + + KA V +T A E+ + +RV Sbjct: 114 RLVGPQMQTNGYGSIINISSVVGVFGNIGQANYAATKAGVIGLTMTWAKEFALKGANVRV 173 Query: 204 NSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGA 263 N++APG I PQ L + L RLG EIA L+LAS ASYVTG Sbjct: 174 NAIAPGYIMTDILKTV---PQDLLDKFAALTMLNRLGQPEEIAKVALFLASDDASYVTGQ 230 Query: 264 VLVADGGAWL 273 + +GG L Sbjct: 231 TINVNGGMRL 240 >1AE1-A nrPDB Length = 273 Score = 236 bits (603), Expect = 7e-63, Method: Composition-based stats. Identities = 60/252 (23%), Positives = 109/252 (43%), Gaps = 5/252 (1%) Query: 25 LLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLS 84 L+ A +TGG GIG+ I E G SR+ + ++ G Sbjct: 18 SLKGTTALVTGGSKGIGYAIVEELAGLGARVYTCSRNEKELDECL-EIWREKGLNVEGSV 76 Query: 85 MDVRAPPAVMAAVDQALKEF-GRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFN 143 D+ + + F G+++IL+N A A + + +M + ++ Sbjct: 77 CDLLSRTERDKLMQTVAHVFDGKLNILVNNAGVVIHKEAKDFTEKDYNIIMGTNFEAAYH 136 Query: 144 VSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRV 203 +S++ Y G ++ +++ G ++K A++ MT+ LA EW NIRV Sbjct: 137 LSQIAYPLLKASQNGNVIFLSSIAGFSALPSVSLYSASKGAINQMTKSLACEWAKDNIRV 196 Query: 204 NSLAPGPISGT---EGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYV 260 NS+APG I +++ + + + +P+ R G E++ + +L P ASY+ Sbjct: 197 NSVAPGVILTPLVETAIKKNPHQKEEIDNFIVKTPMGRAGKPQEVSALIAFLCFPAASYI 256 Query: 261 TGAVLVADGGAW 272 TG ++ ADGG Sbjct: 257 TGQIIWADGGFT 268 >5U9P-A nrPDB Length = 265 Score = 235 bits (600), Expect = 2e-62, Method: Composition-based stats. Identities = 72/254 (28%), Positives = 104/254 (40%), Gaps = 2/254 (0%) Query: 19 HLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGR 78 H L + A ITG G GIG +A G VI R+ + T AR+ G Sbjct: 11 HALDRFRLDGRRALITGSGRGIGLTLARGLAEAGAAIVINDRNEEKAATLARRFRDE-GF 69 Query: 79 RCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDT 138 DV V AA+D+ G IDIL+N A P A + + +M ++ Sbjct: 70 AADHAVFDVAEHAQVRAAIDEFEARVGAIDILVNNAGIQRRAPLDAFEPDDWHALMRVNL 129 Query: 139 SGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGP 198 G FNV++ + G I+NI + + + K AV +T+ + +W Sbjct: 130 DGVFNVAQAVARHMIARGHGKIINICSVQSELARPTIAPYAATKGAVRMLTKGMCADWAR 189 Query: 199 QNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLAS 258 I+ N LAPG TE R L A +P R G E+ + ++LAS + Sbjct: 190 YGIQANGLAPGYFE-TELNRALVDDAAFSDWLCKRTPAGRWGQVDELCGAAIFLASAASD 248 Query: 259 YVTGAVLVADGGAW 272 +V G L DGG Sbjct: 249 FVNGQTLFVDGGLT 262 >2AE2-A nrPDB Length = 260 Score = 234 bits (598), Expect = 3e-62, Method: Composition-based stats. Identities = 66/256 (25%), Positives = 111/256 (43%), Gaps = 4/256 (1%) Query: 20 LFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRR 79 + L A +TGG GIG+ I E G SR+ + + G + Sbjct: 1 MAGRWNLEGCTALVTGGSRGIGYGIVEELASLGASVYTCSRNQKELNDCLTQWRSK-GFK 59 Query: 80 CLPLSMDVRAPPAVMAAVDQALKEF-GRIDILINCAAGNFLCPAGALSFNAFKTVMDIDT 138 D+ + ++ F G+++IL+N A A + + +M I+ Sbjct: 60 VEASVCDLSSRSERQELMNTVANHFHGKLNILVNNAGIVIYKEAKDYTVEDYSLIMSINF 119 Query: 139 SGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGP 198 +++S + + G +V I++ G + G+ K A+D +TR LA EW Sbjct: 120 EAAYHLSVLAHPFLKASERGNVVFISSVSGALAVPYEAVYGATKGAMDQLTRCLAFEWAK 179 Query: 199 QNIRVNSLAPGPISGTEGLRRLGGPQ--ASLSTKVTASPLQRLGNKTEIAHSVLYLASPL 256 NIRVN + PG I+ + + P+ +L+ + L+R+G E+A V +L P Sbjct: 180 DNIRVNGVGPGVIATSLVEMTIQDPEQKENLNKLIDRCALRRMGEPKELAAMVAFLCFPA 239 Query: 257 ASYVTGAVLVADGGAW 272 ASYVTG ++ DGG Sbjct: 240 ASYVTGQIIYVDGGLM 255 >3VZS-A nrPDB Length = 257 Score = 234 bits (597), Expect = 4e-62, Method: Composition-based stats. Identities = 65/248 (26%), Positives = 108/248 (43%), Gaps = 3/248 (1%) Query: 27 RDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMD 86 ++A++TGG GIG I + + G V + A G + + Sbjct: 13 TQRIAYVTGGMGGIGTAICQRLAKDGFRVVAGCGPNSPRREKWLEQQKALGFDFIASEGN 72 Query: 87 VRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSR 146 V + A D+ E G +D+LIN A ++ + V+D + + FNV++ Sbjct: 73 VADWDSTKTAFDKVKSEVGEVDVLINNAGITRDVVFRKMTRADWDAVIDTNLTSLFNVTK 132 Query: 147 VLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSL 206 + + G IVNI++ G +GQ Q + +AKA + T LA E + + VN++ Sbjct: 133 QVIDGMADRGWGRIVNISSVNGQKGQFGQTNYSTAKAGLHGFTMALAQEVATKGVTVNTV 192 Query: 207 APGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLV 266 +PG I+ Q L V P++RLG EIA +L+S + + TGA Sbjct: 193 SPGYIATDM---VKAIRQDVLDKIVATIPVKRLGLPEEIASICAWLSSEESGFSTGADFS 249 Query: 267 ADGGAWLT 274 +GG + Sbjct: 250 LNGGLHMG 257 >6CI9-A nrPDB Length = 259 Score = 232 bits (593), Expect = 9e-62, Method: Composition-based stats. Identities = 77/257 (29%), Positives = 117/257 (45%), Gaps = 7/257 (2%) Query: 18 RHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATG 77 H+F L + A +TGG GIG IAE F G VI R+ + L+G G Sbjct: 1 SHMFTS--LEGRSAIVTGGSKGIGRGIAETFANAGVDVVITGRNQDDLDRTVADLSGTRG 58 Query: 78 RRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDID 137 + + DV P V + + G +DI+ A L+ + + V+ ++ Sbjct: 59 -KVTAVRADVTDPEDARRTVAETVSRHGGLDIVCANAGIFPSGRLEDLTPDDIEQVLGVN 117 Query: 138 TSGTFNVSRVLYEKFFRDHGGVIVNITATLG-NRGQALQVHAGSAKAAVDAMTRHLAVEW 196 GT + + + G +V ++ G G H G++KAA R A+E Sbjct: 118 FKGTVYIVQAALQALTASGHGRVVVTSSITGPITGYPGWSHYGASKAAQLGFLRTAAMEL 177 Query: 197 GPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPL 256 P+ I +N++ PG I TEGL +G Q L +A P RLG+ +I ++ L+ A+ Sbjct: 178 APKKITINAVLPGNIM-TEGLDEMG--QDYLDQMASAIPAGRLGSVADIGNAALFFATDE 234 Query: 257 ASYVTGAVLVADGGAWL 273 A+YVTG LV DGG L Sbjct: 235 AAYVTGQTLVVDGGQVL 251 >3OIC-A nrPDB Length = 258 Score = 231 bits (590), Expect = 2e-61, Method: Composition-based stats. Identities = 64/247 (25%), Positives = 112/247 (45%), Gaps = 1/247 (0%) Query: 27 RDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMD 86 ++K A +TG G+G A +G + VI + + G + L + + Sbjct: 3 QNKCALVTGSSRGVGKAAAIRLAENGYNIVINYARSKKAALETAEEIEKLGVKVLVVKAN 62 Query: 87 VRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSR 146 V P + Q + FGR+D+ +N AA L P L + M+I+ ++ Sbjct: 63 VGQPAKIKEMFQQIDETFGRLDVFVNNAASGVLRPVMELEETHWDWTMNINAKALLFCAQ 122 Query: 147 VLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSL 206 + ++ GG IV+I++ R G +KAA++A+TR+LAVE P+ I VN++ Sbjct: 123 EAAKLMEKNGGGHIVSISSLGSIRYLENYTTVGVSKAALEALTRYLAVELSPKQIIVNAV 182 Query: 207 APGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLV 266 + G I T+ L+ + L +P R+ ++ +V +L S A + G ++ Sbjct: 183 SGGAID-TDALKHFPNREDLLEDARQNTPAGRMVEIKDMVDTVEFLVSSKADMIRGQTII 241 Query: 267 ADGGAWL 273 DGG L Sbjct: 242 VDGGRSL 248 >3V2H-A nrPDB Length = 281 Score = 231 bits (590), Expect = 2e-61, Method: Composition-based stats. Identities = 59/263 (22%), Positives = 106/263 (40%), Gaps = 11/263 (4%) Query: 18 RHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAA-RKLAGAT 76 +L+ ++ K A ITG SGIG IA + G + V+ P + ++AG + Sbjct: 16 ENLYFQSMMT-KTAVITGSTSGIGLAIARTLAKAGANIVLNGFGAPDEIRTVTDEVAGLS 74 Query: 77 GRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDI 136 L D+ P + + FG DIL+N A F+ + ++ + Sbjct: 75 SGTVLHHPADMTKPSEIADMMAMVADRFGGADILVNNAGVQFVEKIEDFPVEQWDRIIAV 134 Query: 137 DTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEW 196 + S +F+ R + G I+NI + G + +AK + +T+ +A+E Sbjct: 135 NLSSSFHTIRGAIPPMKKKGWGRIINIASAHGLVASPFKSAYVAAKHGIMGLTKTVALEV 194 Query: 197 GPQNIRVNSLAPGPISGTEGLRRLGG---------PQASLSTKVTASPLQRLGNKTEIAH 247 + VNS+ PG + +++ Q + P ++ ++A Sbjct: 195 AESGVTVNSICPGYVLTPLVEKQIPDQARTRGITEEQVINEVMLKGQPTKKFITVEQVAS 254 Query: 248 SVLYLASPLASYVTGAVLVADGG 270 LYLA A+ +TG + DGG Sbjct: 255 LALYLAGDDAAQITGTHVSMDGG 277 >1GEG-A nrPDB Length = 256 Score = 230 bits (587), Expect = 5e-61, Method: Composition-based stats. Identities = 72/253 (28%), Positives = 107/253 (42%), Gaps = 10/253 (3%) Query: 28 DKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDV 87 KVA +TG G GIG IA ++ G IA + A ++ A G + + +DV Sbjct: 2 KKVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGH-AVAVKVDV 60 Query: 88 RAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRV 147 V AAV+QA K G D+++N A P +++ V +I+ G + Sbjct: 61 SDRDQVFAAVEQARKTLGGFDVIVNNAGVAPSTPIESITPEIVDKVYNINVKGVIWGIQA 120 Query: 148 LYEKFFR-DHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSL 206 E F + HGG I+N + G+ G S+K AV +T+ A + P I VN Sbjct: 121 AVEAFKKEGHGGKIINACSQAGHVGNPELAVYSSSKFAVRGLTQTAARDLAPLGITVNGY 180 Query: 207 APGPISGTEGLRRLGGPQASL--------STKVTASPLQRLGNKTEIAHSVLYLASPLAS 258 PG + + + L RL ++A V YLASP + Sbjct: 181 CPGIVKTPMWAEIDRQVSEAAGKPLGYGTAEFAKRITLGRLSEPEDVAACVSYLASPDSD 240 Query: 259 YVTGAVLVADGGA 271 Y+TG L+ DGG Sbjct: 241 YMTGQSLLIDGGM 253 >4KMS-A nrPDB Length = 249 Score = 229 bits (583), Expect = 1e-60, Method: Composition-based stats. Identities = 68/245 (27%), Positives = 111/245 (45%), Gaps = 9/245 (3%) Query: 30 VAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRA 89 +A +TGG GIG A G V S AA+++ G + +V Sbjct: 12 IAIVTGGTRGIGKATALELKNKGLTVVANFFSN---YDAAKEMEEKYGIKTKCW--NVAD 66 Query: 90 PPAVMAAVDQALKEFGR-IDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVL 148 AV + +EF + + IL+N A +S + V++++ + FN+S + Sbjct: 67 FEECRQAVKEIEEEFKKPVSILVNNAGITKDKMLHRMSHQDWNDVINVNLNSCFNMSSSV 126 Query: 149 YEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAP 208 E+ G IVNI++ GQ Q + +AKA + T+ LA E +NI VN +AP Sbjct: 127 MEQMRNQDYGRIVNISSINAQAGQVGQTNYSAAKAGIIGFTKALARETASKNITVNCIAP 186 Query: 209 GPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVAD 268 G I+ P+ L+ + + P +RLG EIA +V +L A ++TG + + Sbjct: 187 GYIATEMVGAV---PEDVLAKIINSIPKKRLGQPEEIARAVAFLVDENAGFITGETISIN 243 Query: 269 GGAWL 273 GG + Sbjct: 244 GGHNM 248 >4IIV-A nrPDB Length = 267 Score = 228 bits (582), Expect = 2e-60, Method: Composition-based stats. Identities = 60/256 (23%), Positives = 103/256 (40%), Gaps = 5/256 (1%) Query: 18 RHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATG 77 +L+ + +TG GIG IA G + + A G Sbjct: 16 ENLYFQSNAMSRSVLVTGASKGIGRAIARQLAADGFNIGVHYHRDAAGAQETLNAIVANG 75 Query: 78 RRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDID 137 LS DV ++ + + G +++ A ALS + + V+ + Sbjct: 76 GNGRLLSFDVANREQCREVLEHEIAQHGAWYGVVSNAGIARDAAFPALSNDDWDAVIHTN 135 Query: 138 TSGTFNVSRVLYEKFF-RDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEW 196 +NV + GG I+ +++ G G QV+ +AKA + T+ LA+E Sbjct: 136 LDSFYNVIQPCIMPMIGARQGGRIITLSSVSGVMGNRGQVNYSAAKAGIIGATKALAIEL 195 Query: 197 GPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPL 256 + I VN +APG I + +++L ++ P++R+G E+A YL S + Sbjct: 196 AKRKITVNCIAPGLIDTGM----IEMEESALKEAMSMIPMKRMGQAEEVAGLASYLMSDI 251 Query: 257 ASYVTGAVLVADGGAW 272 A YVT V+ +GG Sbjct: 252 AGYVTRQVISINGGML 267 >5OJG-A nrPDB Length = 260 Score = 228 bits (582), Expect = 2e-60, Method: Composition-based stats. Identities = 65/248 (26%), Positives = 109/248 (43%), Gaps = 3/248 (1%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 KVA +T GIG IAE + G VI SR+ V A L + ++ Sbjct: 8 FEGKVAIVTAATKGIGLAIAERLLDEGASVVIGSRNQKNVDEAIEYLKNKGLTKVAGIAG 67 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNF-LCPAGALSFNAFKTVMDIDTSGTFNV 144 + + VD L++FG+I+IL+N N +S + + +++ F + Sbjct: 68 HIASTDDQKKLVDFTLQKFGKINILVNNHGINPAFGHILEVSDQVWDKLFEVNVKAGFQM 127 Query: 145 SRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVN 204 +++++ ++ GG I+ + + G K + +TR LA+ NIRVN Sbjct: 128 TKLVHPHIAKEGGGAIIFNASYSAYKSPPGIAAYGVTKTTLVGLTRALAMGLAKDNIRVN 187 Query: 205 SLAPGPISGTEGLRRLGGPQASLSTK--VTASPLQRLGNKTEIAHSVLYLASPLASYVTG 262 +APG I G + + + L RLG + A +V YLAS +SY+TG Sbjct: 188 GIAPGVIKTKMSQVLWDGGEDAEKELTDIQEIALGRLGVPDDCAGTVAYLASDDSSYITG 247 Query: 263 AVLVADGG 270 +++ GG Sbjct: 248 EMIIIAGG 255 >4CQL-A nrPDB Length = 261 Score = 228 bits (581), Expect = 2e-60, Method: Composition-based stats. Identities = 64/259 (24%), Positives = 108/259 (41%), Gaps = 11/259 (4%) Query: 23 PDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKL------AGAT 76 + LR +A +TG GSGIG ++ G R L G Sbjct: 6 QNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPP 65 Query: 77 GRRCLPLSMDVRAPPAVMAAVDQALKEFGRI-DILINCAAGNFLCPAGALSFNAFKTVMD 135 DV A ++Q F R ++++CA +S + + V+ Sbjct: 66 RGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIA 125 Query: 136 IDTSGTFNVSRVLYEKFFRDH-GGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAV 194 ++ GTF V++ + + G I+NI++ +G G Q + ++KA V +T+ A Sbjct: 126 VNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAAR 185 Query: 195 EWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLAS 254 E G IR NS+ PG I+ + PQ + P+ LG+ ++A V +LAS Sbjct: 186 ELGRHGIRCNSVLPGFIATPMTQKV---PQKVVDKITEMIPMGHLGDPEDVADVVAFLAS 242 Query: 255 PLASYVTGAVLVADGGAWL 273 + Y+TG + GG ++ Sbjct: 243 EDSGYITGTSVEVTGGLFM 261 >3W8F-A nrPDB Length = 260 Score = 228 bits (581), Expect = 2e-60, Method: Composition-based stats. Identities = 56/256 (21%), Positives = 102/256 (39%), Gaps = 10/256 (3%) Query: 25 LLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAAR-KLAGATGRRCLPL 83 +L+ K A +TG SGIG +A + G VI P + R L G + L Sbjct: 1 MLKGKKAVVTGSTSGIGLAMATELAKAGADVVINGFGQPEDIERERSTLESKFGVKAYYL 60 Query: 84 SMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFN 143 + D+ A + +A + G +DIL+N A P + + ++ ++ S F+ Sbjct: 61 NADLSDAQATRDFIAKAAEALGGLDILVNNAGIQHTAPIEEFPVDKWNAIIALNLSAVFH 120 Query: 144 VSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRV 203 + + G I+NI + G + +AK V +T+ A+E + I Sbjct: 121 GTAAALPIMQKQGWGRIINIASAHGLVASVNKSAYVAAKHGVVGLTKVTALENAGKGITC 180 Query: 204 NSLAPGPISGTEGLRRLGG---------PQASLSTKVTASPLQRLGNKTEIAHSVLYLAS 254 N++ PG + +++ A+ P + ++ + ++L+S Sbjct: 181 NAICPGWVRTPLVEKQIEAISQQKGIDIEAAARELLAEKQPSLQFVTPEQLGGAAVFLSS 240 Query: 255 PLASYVTGAVLVADGG 270 A +TG L DGG Sbjct: 241 AAADQMTGTTLSLDGG 256 >1X1T-A nrPDB Length = 260 Score = 228 bits (581), Expect = 2e-60, Method: Composition-based stats. Identities = 63/256 (24%), Positives = 104/256 (40%), Gaps = 10/256 (3%) Query: 25 LLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARK-LAGATGRRCLPL 83 +L+ KVA +TG SGIG IA G V+ + R LA G + L Sbjct: 1 MLKGKVAVVTGSTSGIGLGIATALAAQGADIVLNGFGDAAEIEKVRAGLAAQHGVKVLYD 60 Query: 84 SMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFN 143 D+ AV VD A+++ GRIDIL+N A + ++ ++ S F+ Sbjct: 61 GADLSKGEAVRGLVDNAVRQMGRIDILVNNAGIQHTALIEDFPTEKWDAILALNLSAVFH 120 Query: 144 VSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRV 203 + + G I+NI + G A + +AK V T+ A+E Q I Sbjct: 121 GTAAALPHMKKQGFGRIINIASAHGLVASANKSAYVAAKHGVVGFTKVTALETAGQGITA 180 Query: 204 NSLAPGPISGTEGLRRLGG---------PQASLSTKVTASPLQRLGNKTEIAHSVLYLAS 254 N++ PG + +++ A+ P + ++ + ++LAS Sbjct: 181 NAICPGWVRTPLVEKQISALAEKNGVDQETAARELLSEKQPSLQFVTPEQLGGTAVFLAS 240 Query: 255 PLASYVTGAVLVADGG 270 A+ +TG + DGG Sbjct: 241 DAAAQITGTTVSVDGG 256 >4CQM-B nrPDB Length = 244 Score = 227 bits (580), Expect = 3e-60, Method: Composition-based stats. Identities = 69/256 (26%), Positives = 106/256 (41%), Gaps = 12/256 (4%) Query: 20 LFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRR 79 + DKV + GG GIG +A++ R G + +R+L AA G G Sbjct: 1 MHHHHHHMDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAA----GDLGGD 56 Query: 80 CLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTS 139 L S DV V ++ K GR++ L+N A N + + + Sbjct: 57 HLAFSCDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLL 116 Query: 140 GTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQ 199 G+ + + GG IVN+ + +G +G + Q ++K + +R LA E + Sbjct: 117 GSMLTCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARK 176 Query: 200 NIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASY 259 IRVN +APG + PL R G E+AH+V++L + Y Sbjct: 177 KIRVNVVAPGFVHTDMT------KDLKEEHLKKNIPLGRFGETIEVAHAVVFLL--ESPY 228 Query: 260 VTGAVLVADGGAWLTF 275 +TG VLV DGG L Sbjct: 229 ITGHVLVVDGGLQLIL 244 >4IS3-A nrPDB Length = 268 Score = 227 bits (579), Expect = 4e-60, Method: Composition-based stats. Identities = 84/255 (32%), Positives = 128/255 (50%), Gaps = 6/255 (2%) Query: 18 RHLFCPDL--LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGA 75 +L+ + ++DKV ITGG GIGF A+IF+ +G I + V TA +L Sbjct: 13 ENLYFQGMNLVQDKVTIITGGTRGIGFAAAKIFIDNGAKVSIFGETQEEVDTALAQLKEL 72 Query: 76 T-GRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVM 134 L + D+ + AVMAAV Q +++GR+D++IN A +S FK +M Sbjct: 73 YPEEEVLGFAPDLTSRDAVMAAVGQVAQKYGRLDVMINNAGITSNNVFSRVSEEEFKHIM 132 Query: 135 DIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAV 194 DI+ +G FN + Y+ GVI+N + G G V ++KA+V +T L Sbjct: 133 DINVTGVFNGAWCAYQCMKDAKKGVIINTASVTGIFGSLSGVGYPASKASVIGLTHGLGR 192 Query: 195 EWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLAS 254 E +NIRV +APG ++ G P + + A P++R+ EIA+ L+LAS Sbjct: 193 EIIRKNIRVVGVAPGVVNTDM---TNGNPPEIMEGYLKALPMKRMLEPEEIANVYLFLAS 249 Query: 255 PLASYVTGAVLVADG 269 LAS +T + DG Sbjct: 250 DLASGITATTVSVDG 264 >2Q2Q-A nrPDB Length = 255 Score = 227 bits (579), Expect = 5e-60, Method: Composition-based stats. Identities = 61/254 (24%), Positives = 102/254 (40%), Gaps = 11/254 (4%) Query: 25 LLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLS 84 L+ K A +TG SGIG IA++ R G + V+ P A G + + Sbjct: 1 TLKGKTALVTGSTSGIGLGIAQVLARAGANIVLNGFGDP---APALAEIARHGVKAVHHP 57 Query: 85 MDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNV 144 D+ + A A +EFG +DIL+N A + P ++ ++ ++ S F+ Sbjct: 58 ADLSDVAQIEALFALAEREFGGVDILVNNAGIQHVAPVEQFPLESWDKIIALNLSAVFHG 117 Query: 145 SRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVN 204 +R+ + G I+NI + G G + +AK V +T+ + +E N+ N Sbjct: 118 TRLALPGMRARNWGRIINIASVHGLVGSTGKAAYVAAKHGVVGLTKVVGLETATSNVTCN 177 Query: 205 SLAPGPISGTEGLRRLGGP--------QASLSTKVTASPLQRLGNKTEIAHSVLYLASPL 256 ++ PG + +++ QA P + VL+L S Sbjct: 178 AICPGWVLTPLVQKQIDDRAANGGDPLQAQHDLLAEKQPSLAFVTPEHLGELVLFLCSEA 237 Query: 257 ASYVTGAVLVADGG 270 S V GA DGG Sbjct: 238 GSQVRGAAWNVDGG 251 >4DBZ-A nrPDB Length = 281 Score = 227 bits (578), Expect = 6e-60, Method: Composition-based stats. Identities = 67/268 (25%), Positives = 111/268 (41%), Gaps = 14/268 (5%) Query: 14 LPAYRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLA 73 +P H+ D +VA +TG SGIG IA + G + +R + T ++L Sbjct: 15 VPRGSHMATQDS---EVALVTGATSGIGLEIARRLGKEGLRVFVCARGEEGLRTTLKELR 71 Query: 74 GATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTV 133 A G + DVR+ P + A V ++ +G +D+L+N A L+ + V Sbjct: 72 EA-GVEADGRTCDVRSVPEIEALVAAVVERYGPVDVLVNNAGRPGGGATAELADELWLDV 130 Query: 134 MDIDTSGTFNVSRVLYEK--FFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRH 191 ++ + +G F V++ + + G IVNI +T G +G ++K V T+ Sbjct: 131 VETNLTGVFRVTKQVLKAGGMLERGTGRIVNIASTGGKQGLVHAAPYSASKHGVVGFTKA 190 Query: 192 LAVEWGPQNIRVNSLAPGPISGTEGLRRLG--------GPQASLSTKVTASPLQRLGNKT 243 L +E I VN++ PG + + + P+ R + Sbjct: 191 LGLELARTGITVNAVCPGFVETPMAASVREHYSDIWEVSTEEAFDRITARVPIGRYVQPS 250 Query: 244 EIAHSVLYLASPLASYVTGAVLVADGGA 271 E+A V YL P A+ VT L GG Sbjct: 251 EVAEMVAYLIGPGAAAVTAQALNVCGGL 278 >3R3S-A nrPDB Length = 294 Score = 226 bits (577), Expect = 8e-60, Method: Composition-based stats. Identities = 72/279 (25%), Positives = 112/279 (40%), Gaps = 12/279 (4%) Query: 3 QPPPDVEGD-----DCLPAYRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVI 57 QP P V+ DC + L+D+ A +TGG SGIG A + R G I Sbjct: 21 QPAPGVQAKMTPVPDC--GEKSYVGSGRLKDRKALVTGGDSGIGRAAAIAYAREGADVAI 78 Query: 58 ASRSLPRVLTA-ARKLAGATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAG 116 + L GR+ + L D+ + V +A + G +DIL A Sbjct: 79 NYLPAEEEDAQQVKALIEECGRKAVLLPGDLSDESFARSLVHKAREALGGLDILALVAGK 138 Query: 117 NFLCP-AGALSFNAFKTVMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQ 175 P L+ F+ ++ F +++ G I+ ++ + Sbjct: 139 QTAIPEIKDLTSEQFQQTFAVNVFALFWITQEAIPLL--PKGASIITTSSIQAYQPSPHL 196 Query: 176 VHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASP 235 + + KAA+ +R LA + + IRVN +APGPI + G Q + +P Sbjct: 197 LDYAATKAAILNYSRGLAKQVAEKGIRVNIVAPGPIWTALQISG-GQTQDKIPQFGQQTP 255 Query: 236 LQRLGNKTEIAHSVLYLASPLASYVTGAVLVADGGAWLT 274 ++R G E+A +YLAS +SYVT V GG L Sbjct: 256 MKRAGQPAELAPVYVYLASQESSYVTAEVHGVCGGEHLG 294 >4Z9Y-A nrPDB Length = 253 Score = 225 bits (575), Expect = 1e-59, Method: Composition-based stats. Identities = 74/257 (28%), Positives = 122/257 (47%), Gaps = 6/257 (2%) Query: 20 LFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRR 79 + L+ KVA ITG +G+G +A + GC V + P+ + A GRR Sbjct: 2 ILNSFDLQGKVALITGCDTGLGQGMAIGLAQAGCDIVGVNIVEPK---DTIEKVTALGRR 58 Query: 80 CLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTS 139 L L+ D+ V++A+ EFG +DIL+N A A S + VM+++ Sbjct: 59 FLSLTADMSNVSGHAELVEKAVAEFGHVDILVNNAGIIRREDAIEFSEKNWDDVMNLNIK 118 Query: 140 GTFNVSRVLYEKFFRDH-GGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGP 198 F +S+ + +F + GG I+NI + L +G ++K+AV +TR +A EW Sbjct: 119 SVFFMSQTVARQFIKQGKGGKIINIASMLSFQGGIRVPSYTASKSAVMGVTRLMANEWAK 178 Query: 199 QNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLAS 258 I VN++APG ++ T ++L + + P R G ++ ++LAS + Sbjct: 179 HGINVNAIAPGYMA-TNNTQQLRADEERSKEILDRIPAGRWGLPQDLMGPSVFLASSASD 237 Query: 259 YVTGAVLVADGGAWLTF 275 Y+ G + DGG WL Sbjct: 238 YINGYTIAVDGG-WLAR 253 >2B4Q-A nrPDB Length = 276 Score = 224 bits (572), Expect = 3e-59, Method: Composition-based stats. Identities = 67/265 (25%), Positives = 114/265 (43%), Gaps = 8/265 (3%) Query: 14 LPAYRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLA 73 +P H+ L ++A +TGG GIG IA+ + G I +R A +L+ Sbjct: 15 VPRGSHMHPYFSLAGRIALVTGGSRGIGQMIAQGLLEAGARVFICARDAEACADTATRLS 74 Query: 74 GATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTV 133 C + D+ + + R+DIL+N A ++ + + ++ V Sbjct: 75 AY--GDCQAIPADLSSEAGARRLAQALGELSARLDILVNNAGTSWGAALESYPVSGWEKV 132 Query: 134 MDIDTSGTFNVSRVLYEKFFR----DHGGVIVNITATLGNRGQALQVH-AGSAKAAVDAM 188 M ++ + F+ + L R ++ ++NI + G Q + G +KAA+ + Sbjct: 133 MQLNVTSVFSCIQQLLPLLRRSASAENPARVINIGSVAGISAMGEQAYAYGPSKAALHQL 192 Query: 189 TRHLAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHS 248 +R LA E ++I VN +APG PQA L + P+ R G E+A Sbjct: 193 SRMLAKELVGEHINVNVIAPGRFPSRMTRHIANDPQA-LEADSASIPMGRWGRPEEMAAL 251 Query: 249 VLYLASPLASYVTGAVLVADGGAWL 273 + LA +Y+TG V+ DGG L Sbjct: 252 AISLAGTAGAYMTGNVIPIDGGFHL 276 >5OVL-A nrPDB Length = 300 Score = 224 bits (571), Expect = 4e-59, Method: Composition-based stats. Identities = 62/246 (25%), Positives = 102/246 (41%), Gaps = 15/246 (6%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVR 88 + +TGG GIG IA G + R + DV Sbjct: 69 RSVLVTGGNRGIGLAIARRLAADGHKVAVTHRGS------------GAPDDLFGVQCDVT 116 Query: 89 APPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVL 148 AV A + + G +++L+ A + ++ F+ V++ + +G F ++ Sbjct: 117 DSAAVDRAFKEVEEHQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRCAQRA 176 Query: 149 YEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAP 208 R G I+ I + G G Q + +AKA + M R ++ E + N +AP Sbjct: 177 SRTMQRKRFGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTANVVAP 236 Query: 209 GPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVAD 268 G I TE R L + + + P +R+G E+A +V +LAS ASY+ GAV+ D Sbjct: 237 GYID-TEMTRAL--DERIQAGALDFIPAKRVGTAEEVAGAVSFLASEDASYIAGAVIPVD 293 Query: 269 GGAWLT 274 GG + Sbjct: 294 GGMGMG 299 >1AHH-A nrPDB Length = 255 Score = 224 bits (570), Expect = 5e-59, Method: Composition-based stats. Identities = 76/253 (30%), Positives = 129/253 (50%), Gaps = 6/253 (2%) Query: 20 LFCPDLLR--DKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATG 77 +F D LR K A ITG G+GIG IA F G V++ + ++ G Sbjct: 1 MFNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEI-QQLG 59 Query: 78 RRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDID 137 + D+ + + A D A+ + G++DIL+N A G P + F+ +++ Sbjct: 60 GQAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPKPF-DMPMADFRRAYELN 118 Query: 138 TSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWG 197 F++S+++ + ++ GGVI+ IT+ S+KAA + R++A + G Sbjct: 119 VFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLG 178 Query: 198 PQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLA 257 +NIRVN +APG I T+ L+ + P+ + +P++RLG +IA++ L+L SP A Sbjct: 179 EKNIRVNGIAPGAIL-TDALKSVITPEIE-QKMLQHTPIRRLGQPQDIANAALFLCSPAA 236 Query: 258 SYVTGAVLVADGG 270 S+V+G +L GG Sbjct: 237 SWVSGQILTVSGG 249 >3V2G-A nrPDB Length = 271 Score = 223 bits (568), Expect = 9e-59, Method: Composition-based stats. Identities = 68/256 (26%), Positives = 101/256 (39%), Gaps = 7/256 (2%) Query: 17 YRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGAT 76 ++ + L K AF+TGG GIG IA+ G + + A Sbjct: 20 FQSMMTSISLAGKTAFVTGGSRGIGAAIAKRLALEGAAVALTYVNAAERAQAVVSEIEQA 79 Query: 77 GRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDI 136 G R + + D R A+ A+ + ++ G +DIL+N A P + F VM + Sbjct: 80 GGRAVAIRADNRDAEAIEQAIRETVEALGGLDILVNSAGIWHSAPLEETTVADFDEVMAV 139 Query: 137 DTSGTFNVSRVLYEKFFRDHGGVIVNITATLG-NRGQALQVHAGSAKAAVDAMTRHLAVE 195 + F R GG I+ I + L ++KAA+ +T+ LA + Sbjct: 140 NFRAPFVAIRSASRHL--GDGGRIITIGSNLAELVPWPGISLYSASKAALAGLTKGLARD 197 Query: 196 WGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASP 255 GP+ I VN + PG +A T G +IA V +LA P Sbjct: 198 LGPRGITVNIVHPGSTDTDMNPADGDHAEAQRERIAT----GSYGEPQDIAGLVAWLAGP 253 Query: 256 LASYVTGAVLVADGGA 271 +VTGA L DGGA Sbjct: 254 QGKFVTGASLTIDGGA 269 >3U5T-A nrPDB Length = 267 Score = 222 bits (567), Expect = 1e-58, Method: Composition-based stats. Identities = 77/254 (30%), Positives = 113/254 (44%), Gaps = 5/254 (1%) Query: 18 RHLFCPDLLR-DKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGAT 76 +L+ ++ +KVA +TG GIG IA G VI A Sbjct: 16 ENLYFQSMMETNKVAIVTGASRGIGAAIAARLASDGFTVVINYAGKAAAAEEVAGKIEAA 75 Query: 77 GRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDI 136 G + L DV P AV A + FG +D+L+N A L F V+ + Sbjct: 76 GGKALTAQADVSDPAAVRRLFATAEEAFGGVDVLVNNAGIMPLTTIAETGDAVFDRVIAV 135 Query: 137 DTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEW 196 + GTFN R ++ GG I+N++ + +AKA V+AMT L+ E Sbjct: 136 NLKGTFNTLREAAQRL--RVGGRIINMSTSQVGLLHPSYGIYAAAKAGVEAMTHVLSKEL 193 Query: 197 GPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPL 256 ++I VN++APGP + L G +PL+RLG +IA +V +LA P Sbjct: 194 RGRDITVNAVAPGPTATDLFLE--GKSDEVRDRFAKLAPLERLGTPQDIAGAVAFLAGPD 251 Query: 257 ASYVTGAVLVADGG 270 ++V G VL A+GG Sbjct: 252 GAWVNGQVLRANGG 265 >4MOW-A nrPDB Length = 256 Score = 222 bits (566), Expect = 1e-58, Method: Composition-based stats. Identities = 70/246 (28%), Positives = 108/246 (43%), Gaps = 2/246 (0%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L KVA +TG GIG IA+ G V+ S A G R + + Sbjct: 12 LAGKVAIVTGASKGIGAAIAKALADEGAAVVVNYASSKAGADAVVSAITEAGGRAVAVGG 71 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 DV VD A++ +GR+D+L+N + P A++ ++ D + G + Sbjct: 72 DVSKAADAQRIVDTAIETYGRLDVLVNNSGVYEFAPIEAITEEHYRRQFDTNVFGVLLTT 131 Query: 146 RVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNS 205 + + G I+NI++ + + K AVDA+T LA+E GP+ IRVN+ Sbjct: 132 QAAVKHL--GEGASIINISSVVTSITPPASAVYSGTKGAVDAITGVLALELGPRKIRVNA 189 Query: 206 LAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVL 265 + PG I + + +PL RLG +IA ++LAS A ++TG L Sbjct: 190 INPGMIVTEGTHSAGIIGSDLEAQVLGQTPLGRLGEPNDIASVAVFLASDDARWMTGEHL 249 Query: 266 VADGGA 271 V GG Sbjct: 250 VVSGGL 255 >5T5Q-A nrPDB Length = 247 Score = 222 bits (565), Expect = 2e-58, Method: Composition-based stats. Identities = 69/250 (27%), Positives = 110/250 (44%), Gaps = 8/250 (3%) Query: 24 DLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPL 83 ++ +TG GIG IAE+F G + V+ + A L R + Sbjct: 5 FEFENRTLVLTGANGGIGRAIAELFHASGANLVLTDLDREGLDAFAASLGSP--ERIATI 62 Query: 84 SMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFN 143 D + V A++ FG ID L+ A P +S + + I+ G F Sbjct: 63 KADASSADDAEKTVALAMERFGGIDFLVPSAGIYQAKPFAEMSDADWHRTISINLDGVFY 122 Query: 144 VSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRV 203 + + D IV + + RG + H G+ K A+ +MTR L+ E P+ RV Sbjct: 123 LCKRALPALKED--SSIVTLASLAAYRGAYVNAHYGATKGAMVSMTRALSRELAPK-TRV 179 Query: 204 NSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGA 263 N ++PG I L + + +T +PL+RLG +EIA + +L SP AS+VTG Sbjct: 180 NGVSPGIIETPMTSELL---KTRMDETMTQTPLKRLGKPSEIASVIAFLCSPAASFVTGE 236 Query: 264 VLVADGGAWL 273 + +GG ++ Sbjct: 237 TIQVNGGIYM 246 >1K2W-A nrPDB Length = 256 Score = 221 bits (564), Expect = 3e-58, Method: Composition-based stats. Identities = 72/258 (27%), Positives = 118/258 (45%), Gaps = 13/258 (5%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L K A ITG GIG AE ++R G IA +L A ++ G +++ Sbjct: 3 LDGKTALITGSARGIGRAFAEAYVREGARVAIADINLEAARATAAEI----GPAACAIAL 58 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 DV ++ V + L +G IDIL+N AA L P ++ ++ + I+ SGT + Sbjct: 59 DVTDQASIDRCVAELLDRWGSIDILVNNAALFDLAPIVEITRESYDRLFAINVSGTLFMM 118 Query: 146 RVLYEKFFR-DHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVN 204 + + GG I+N+ + G RG+AL + KAAV ++T+ + I VN Sbjct: 119 QAVARAMIAGGRGGKIINMASQAGRRGEALVGVYCATKAAVISLTQSAGLNLIRHGINVN 178 Query: 205 SLAPGPISGT-------EGLRRLGGPQASLSTKV-TASPLQRLGNKTEIAHSVLYLASPL 256 ++APG + G + P+ +V A P R+G ++ ++LA+P Sbjct: 179 AIAPGVVDGEHWDGVDAKFADYENLPRGEKKRQVGAAVPFGRMGRAEDLTGMAIFLATPE 238 Query: 257 ASYVTGAVLVADGGAWLT 274 A Y+ DGG W++ Sbjct: 239 ADYIVAQTYNVDGGNWMS 256 >5YSS-A nrPDB Length = 256 Score = 221 bits (563), Expect = 3e-58, Method: Composition-based stats. Identities = 59/253 (23%), Positives = 104/253 (41%), Gaps = 11/253 (4%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L K A +TG SGIG IA++ + G ++ + AA+ G+ Sbjct: 3 LTGKTALVTGSTSGIGLGIAQVLAQAGATLILNGFGD---VDAAKDAVAQYGKTPGYHGA 59 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 D+ + + A EFG +DILIN A + P + + ++ I+ S F+ + Sbjct: 60 DLSDEAQIADMMRYAESEFGGVDILINNAGIQHVSPIETFPVDKWNAIIAINLSSVFHTT 119 Query: 146 RVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNS 205 R+ + G I+NI + G + +AK V +T+ +A+E I N+ Sbjct: 120 RLALPGMRARNWGRIINIASVHGLVASKEKSAYVAAKHGVVGLTKTIALETAQTEITCNA 179 Query: 206 LAPGPISGTEGLRRL-------GGPQASLSTKVT-ASPLQRLGNKTEIAHSVLYLASPLA 257 L PG + +++ P+A+ + P + ++ + L+L S A Sbjct: 180 LCPGWVLTPLVQQQIDKRIAEGAEPEAARDALLAEKQPSREFVTPEQLGNLALFLCSDGA 239 Query: 258 SYVTGAVLVADGG 270 + V G DGG Sbjct: 240 AQVRGVAWNMDGG 252 >1NFF-A nrPDB Length = 260 Score = 220 bits (562), Expect = 4e-58, Method: Composition-based stats. Identities = 66/248 (26%), Positives = 107/248 (43%), Gaps = 12/248 (4%) Query: 23 PDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLP 82 L KVA ++GG G+G + G V + + +A Sbjct: 2 SGRLTGKVALVSGGARGMGASHVRAMVAEGAKVVFGDI----LDEEGKAMAAELADAARY 57 Query: 83 LSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTF 142 + +DV P AAVD A+ FG + +L+N A + + ++ ++D++ +G F Sbjct: 58 VHLDVTQPAQWKAAVDTAVTAFGGLHVLVNNAGILNIGTIEDYALTEWQRILDVNLTGVF 117 Query: 143 NVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIR 202 R + + G I+NI++ G G + K AV +T+ A+E GP IR Sbjct: 118 LGIRAVVKPMKEAGRGSIINISSIEGLAGTVACHGYTATKFAVRGLTKSTALELGPSGIR 177 Query: 203 VNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTG 262 VNS+ PG + + + + L R E+++ V+YLAS +SY TG Sbjct: 178 VNSIHPGLVKTPMT--------DWVPEDIFQTALGRAAEPVEVSNLVVYLASDESSYSTG 229 Query: 263 AVLVADGG 270 A V DGG Sbjct: 230 AEFVVDGG 237 >3WYE-A nrPDB Length = 256 Score = 220 bits (560), Expect = 6e-58, Method: Composition-based stats. Identities = 70/254 (27%), Positives = 111/254 (43%), Gaps = 12/254 (4%) Query: 28 DKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDV 87 KVA +TG G GIG IA ++ G IA + A ++ A G + + +DV Sbjct: 2 KKVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGH-AVAVKVDV 60 Query: 88 RAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRV 147 V AAV+QA K G D+++N A + P ++ K + ++ F + Sbjct: 61 SDRDQVFAAVEQARKTLGGFDVIVNNAGIAQIKPLLEVTEEDLKQIYSVNVFSVFFGIQA 120 Query: 148 LYEKFFR-DHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSL 206 E F + HGG I+N + +G + + K AV +T+ A + P I VN Sbjct: 121 AVEAFKKEGHGGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQTAARDLAPLGITVNGY 180 Query: 207 APGPISGTEGLRRLGGPQASL---------STKVTASPLQRLGNKTEIAHSVLYLASPLA 257 PG I GT ++ + + ++ L R ++A V +LASP + Sbjct: 181 CPG-IVGTGMWEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDVAGLVSFLASPDS 239 Query: 258 SYVTGAVLVADGGA 271 Y+TG L+ DGG Sbjct: 240 DYMTGQSLLIDGGM 253 >5OVJ-A nrPDB Length = 256 Score = 220 bits (560), Expect = 7e-58, Method: Composition-based stats. Identities = 62/246 (25%), Positives = 102/246 (41%), Gaps = 15/246 (6%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVR 88 + +TGG GIG IA G + R + DV Sbjct: 25 RSVLVTGGNRGIGLAIARRLAADGHKVAVTHRGS------------GAPDDLFGVQCDVT 72 Query: 89 APPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVL 148 AV A + + G +++L+ A + ++ F+ V++ + +G F ++ Sbjct: 73 DSAAVDRAFKEVEEHQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRCAQRA 132 Query: 149 YEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAP 208 R G I+ I + G G Q + +AKA + M R ++ E + N +AP Sbjct: 133 SRTMQRKRFGRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTANVVAP 192 Query: 209 GPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVAD 268 G I TE R L + + + P +R+G E+A +V +LAS ASY+ GAV+ D Sbjct: 193 GYID-TEMTRAL--DERIQAGALDFIPAKRVGTAEEVAGAVSFLASEDASYIAGAVIPVD 249 Query: 269 GGAWLT 274 GG + Sbjct: 250 GGMGMG 255 >3UVE-A nrPDB Length = 286 Score = 220 bits (560), Expect = 7e-58, Method: Composition-based stats. Identities = 70/280 (25%), Positives = 110/280 (39%), Gaps = 29/280 (10%) Query: 24 DLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASR---------------SLPRVLTA 68 + KVAF+TG G G A + G + S P L Sbjct: 7 GRVEGKVAFVTGAARGQGRSHAVRLAQEGADIIAVDICKPIRAGVVDTAIPASTPEDLAE 66 Query: 69 ARKLAGATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAA-GNFLCPAGALSF 127 L RR + +DVR A+ AAVD +++ GR+DI++ A GN S Sbjct: 67 TADLVKGHNRRIVTAEVDVRDYDALKAAVDSGVEQLGRLDIIVANAGIGNGGDTLDKTSE 126 Query: 128 NAFKTVMDIDTSGTFNVSRVLYEKFFRD-HGGVIVNITATLGNRGQALQVHAGSAKAAVD 186 + ++DI+ +G + + GG I+ ++ G + H +AK V Sbjct: 127 EDWTEMIDINLAGVWKTVKAGVPHMIAGGRGGSIILTSSVGGLKAYPHTGHYVAAKHGVV 186 Query: 187 AMTRHLAVEWGPQNIRVNSLAPGPISGT----EGLRRLGGPQASLSTKVTASPLQR---- 238 + R VE G IRVNS+ P + EG ++ P +P+ + Sbjct: 187 GLMRAFGVELGQHMIRVNSVHPTHVKTPMLHNEGTFKMFRPDLENPGPDDMAPICQMFHT 246 Query: 239 ----LGNKTEIAHSVLYLASPLASYVTGAVLVADGGAWLT 274 +I+++VL+ AS A Y+TG L D G+ L Sbjct: 247 LPIPWVEPIDISNAVLFFASDEARYITGVTLPIDAGSCLK 286 >1DOH-A nrPDB Length = 283 Score = 219 bits (559), Expect = 9e-58, Method: Composition-based stats. Identities = 66/263 (25%), Positives = 110/263 (41%), Gaps = 13/263 (4%) Query: 22 CPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCL 81 L KVA +TG G GIG +A R GC ++ + G Sbjct: 23 QSASLEGKVALVTGAGRGIGREMAMELGRRGCKVIVNYANSTESAEEVVAAIKKNGSDAA 82 Query: 82 PLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGT 141 + +V ++ ++A+K FG++DI+ + + ++ F V I+T G Sbjct: 83 CVKANVGVVEDIVRMFEEAVKIFGKLDIVCSNSGVVSFGHVKDVTPEEFDRVFTINTRGQ 142 Query: 142 FNVSRVLYEKFFRDHGGVIVNITATLGN-RGQALQVHAGSAKAAVDAMTRHLAVEWGPQN 200 F V+R Y+ + GG ++ + + G + +K A++ R +A++ + Sbjct: 143 FFVAREAYKHL--EIGGRLILMGSITGQAKAVPKHAVYSGSKGAIETFARCMAIDMADKK 200 Query: 201 IRVNSLAPGPISGTE----------GLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVL 250 I VN +APG I L + V SPL+R+G +IA V Sbjct: 201 ITVNVVAPGGIKTDMYHAVCREYIPNGENLSNEEVDEYAAVQWSPLRRVGLPIDIARVVC 260 Query: 251 YLASPLASYVTGAVLVADGGAWL 273 +LAS +VTG V+ DGGA + Sbjct: 261 FLASNDGGWVTGKVIGIDGGACM 283 >4E6P-A nrPDB Length = 259 Score = 219 bits (558), Expect = 1e-57, Method: Composition-based stats. Identities = 72/258 (27%), Positives = 118/258 (45%), Gaps = 13/258 (5%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L K A ITG GIG AE ++R G IA + R AA ++ G + M Sbjct: 6 LEGKSALITGSARGIGRAFAEAYVREGATVAIADIDIERARQAAAEI----GPAAYAVQM 61 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 DV ++ AA+ ++ G +DIL+N AA L P ++ +++ + I+ +GT Sbjct: 62 DVTRQDSIDAAIAATVEHAGGLDILVNNAALFDLAPIVEITRESYEKLFAINVAGTLFTL 121 Query: 146 RVLYEKFFRD-HGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVN 204 + + GG I+N+ + G RG+AL + KAAV ++T+ ++ I VN Sbjct: 122 QAAARQMIAQGRGGKIINMASQAGRRGEALVAIYCATKAAVISLTQSAGLDLIKHRINVN 181 Query: 205 SLAPGPISGT-------EGLRRLGGPQASLSTKV-TASPLQRLGNKTEIAHSVLYLASPL 256 ++APG + G R P+ V A P R+G ++ ++LAS Sbjct: 182 AIAPGVVDGEHWDGVDALFARYENRPRGEKKRLVGEAVPFGRMGTAEDLTGMAIFLASAE 241 Query: 257 ASYVTGAVLVADGGAWLT 274 + Y+ DGG W++ Sbjct: 242 SDYIVSQTYNVDGGNWMS 259 >3T7C-A nrPDB Length = 299 Score = 218 bits (556), Expect = 2e-57, Method: Composition-based stats. Identities = 75/274 (27%), Positives = 118/274 (43%), Gaps = 25/274 (9%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIAS-----------RSLPRVLTAARKLAG 74 + KVAFITG G G A R G + S P L + Sbjct: 26 VEGKVAFITGAARGQGRSHAITLAREGADIIAIDVCKQLDGVKLPMSTPDDLAETVRQVE 85 Query: 75 ATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAA-GNFLCPAGALSFNAFKTV 133 A GRR + +DVR A+ AAVD + + GR+DI++ AA + + ++ + Sbjct: 86 ALGRRIIASQVDVRDFDAMQAAVDDGVTQLGRLDIVLANAALASEGTRLNRMDPKTWRDM 145 Query: 134 MDIDTSGTFNVSRVLYEK-FFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHL 192 +D++ +G + +RV GG IV ++ G RG + ++K + + R + Sbjct: 146 IDVNLNGAWITARVAIPHIMAGKRGGSIVFTSSIGGLRGAENIGNYIASKHGLHGLMRTM 205 Query: 193 AVEWGPQNIRVNSLAPGPISGTEGL----RRLGGPQASLSTKVTASPLQR--------LG 240 A+E GP+NIRVN + P ++ L R+ P T R Sbjct: 206 ALELGPRNIRVNIVCPSSVATPMLLNEPTYRMFRPDLENPTVEDFQVASRQMHVLPIPYV 265 Query: 241 NKTEIAHSVLYLASPLASYVTGAVLVADGGAWLT 274 +I++++L+L S A Y+TG L DGGA L Sbjct: 266 EPADISNAILFLVSDDARYITGVSLPVDGGALLK 299 >2CFC-A nrPDB Length = 250 Score = 217 bits (554), Expect = 4e-57, Method: Composition-based stats. Identities = 73/244 (29%), Positives = 109/244 (44%), Gaps = 4/244 (1%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVR 88 +VA +TG SG G IA F+ G S + AR A + L + DV Sbjct: 3 RVAIVTGASSGNGLAIATRFLARGDRVAALDLSAETLEETARTHWHAYADKVLRVRADVA 62 Query: 89 APPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGAL---SFNAFKTVMDIDTSGTFNVS 145 V AA+ +++FG ID+L+N A AG L F VM ++ G F Sbjct: 63 DEGDVNAAIAATMEQFGAIDVLVNNAGITGNSEAGVLHTTPVEQFDKVMAVNVRGIFLGC 122 Query: 146 RVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNS 205 R + GVIVNI + + ++K AV +T+ +AV++ IR N+ Sbjct: 123 RAVLPHMLLQGAGVIVNIASVASLVAFPGRSAYTTSKGAVLQLTKSVAVDYAGSGIRCNA 182 Query: 206 LAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVL 265 + PG I RL P+ + P + +G ++A +V++LA A+YV GA L Sbjct: 183 VCPGMIETPMTQWRLDQPE-LRDQVLARIPQKEIGTAAQVADAVMFLAGEDATYVNGAAL 241 Query: 266 VADG 269 V DG Sbjct: 242 VMDG 245 >4HP8-A nrPDB Length = 247 Score = 217 bits (552), Expect = 5e-57, Method: Composition-based stats. Identities = 72/257 (28%), Positives = 108/257 (42%), Gaps = 11/257 (4%) Query: 20 LFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRR 79 + P L + A +TG +G+G IA G V A+R P + G Sbjct: 1 MKNPFSLEGRKALVTGANTGLGQAIAVGLAAAGAEVVCAARRAPD---ETLDIIAKDGGN 57 Query: 80 CLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTS 139 L +D P A + A DIL+N A + S + VMD++ Sbjct: 58 ASALLIDFADPLAAKDSFTDA-----GFDILVNNAGIIRRADSVEFSELDWDEVMDVNLK 112 Query: 140 GTFNVSRVLYEKFF-RDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGP 198 F ++ ++ + G +VNI + L +G +AK V +T+ LA EW Sbjct: 113 ALFFTTQAFAKELLAKGRSGKVVNIASLLSFQGGIRVPSYTAAKHGVAGLTKLLANEWAA 172 Query: 199 QNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLAS 258 + I VN++APG I T L A + P R G+ +IA + ++L+S A Sbjct: 173 KGINVNAIAPGYIE-TNNTEALRADAARNKAILERIPAGRWGHSEDIAGAAVFLSSAAAD 231 Query: 259 YVTGAVLVADGGAWLTF 275 YV GA+L DGG WL Sbjct: 232 YVHGAILNVDGG-WLAR 247 >1W73-A nrPDB Length = 302 Score = 217 bits (552), Expect = 5e-57, Method: Composition-based stats. Identities = 91/257 (35%), Positives = 134/257 (52%), Gaps = 1/257 (0%) Query: 15 PAYRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAG 74 P + + P+ + KVAFITGGG+G+G + + G VIASR + + A +++ Sbjct: 13 PLQKAMLPPNSFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISS 72 Query: 75 ATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVM 134 TG + + DVR P V V + +K G +I+IN AAGNF+ P LS NA+KT+ Sbjct: 73 QTGNKVHAIQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTIT 132 Query: 135 DIDTSGTFNVSRVLYEKFFRDHGG-VIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLA 193 DI +GT V+ + ++ + G ++IT G V + SAKA V+AM++ LA Sbjct: 133 DIVLNGTAFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLA 192 Query: 194 VEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLA 253 EWG +R N + PGPI RL + P RLG E+A+ +L Sbjct: 193 AEWGKYGMRFNVIQPGPIKTKGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFLC 252 Query: 254 SPLASYVTGAVLVADGG 270 S AS++ GAV+ DGG Sbjct: 253 SDYASWINGAVIKFDGG 269 >5B1Y-A nrPDB Length = 270 Score = 216 bits (551), Expect = 8e-57, Method: Composition-based stats. Identities = 63/260 (24%), Positives = 113/260 (43%), Gaps = 10/260 (3%) Query: 14 LPAYRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLA 73 +P H+ A +TGG GIG F R G VIA +S + + A Sbjct: 15 VPRGSHMETTY------ALVTGGSRGIGRATVLRFAREGWSVVIAYKSRADLAEKTAEEA 68 Query: 74 GATGR-RCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKT 132 G + +DV P +V + + +++L+N A L S + ++ Sbjct: 69 RRLGSPEAYTVRVDVGDPDSVTEMSSRVGELIPHLNVLVNAAGVLQLGGIEETSISEWEE 128 Query: 133 VMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQAL-QVHAGSAKAAVDAMTRH 191 + ++ +G + V+++L + IVN+ + G G + V ++KA V +T+ Sbjct: 129 TLRVNLTGVYLVTKLLLPLLRKAKWASIVNVASIAGETGNVVAGVAYSASKAGVIGLTKR 188 Query: 192 LAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLY 251 LAV+ IRVN++AP + T+ R + PL+ + ++A ++L+ Sbjct: 189 LAVQLAGYGIRVNAVAPSFVE-TDMTRSFLDTPEKRERIASLHPLKIILKPEDVAEAILF 247 Query: 252 LASP-LASYVTGAVLVADGG 270 LA P + +TG VL + G Sbjct: 248 LADPRRSRGITGHVLSINAG 267 >4RZI-B nrPDB Length = 240 Score = 216 bits (550), Expect = 9e-57, Method: Composition-based stats. Identities = 63/245 (25%), Positives = 98/245 (40%), Gaps = 15/245 (6%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L DKV +TGG GIG I ++ G + T L + Sbjct: 6 LEDKVIVVTGGNRGIGAAIVKLLQEMGAKVAFTDLATDGGNT-----------EALGVVA 54 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 +V ++ AA + + G + ++ A L+ + V++++ G Sbjct: 55 NVTDLESMTAAAAEITDKLGPVYGVVANAGITKDNFFPKLTPADWDAVLNVNLKGVAYSI 114 Query: 146 RVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNS 205 + E + G IV I++ G RG Q + + KA V M + LA E +R N+ Sbjct: 115 KPFIEGMYERKAGSIVAISSISGERGNVGQTNYSATKAGVIGMMKSLAREGARYGVRANA 174 Query: 206 LAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASP-LASYVTGAV 264 +APG I L + P +R G EIA +V +L SP +SYVTG V Sbjct: 175 VAPGFIDTEM---TLAIREDIREKITKEIPFRRFGKPEEIAWAVAFLLSPVASSYVTGEV 231 Query: 265 LVADG 269 L +G Sbjct: 232 LRVNG 236 >3WTC-A nrPDB Length = 262 Score = 216 bits (550), Expect = 1e-56, Method: Composition-based stats. Identities = 66/264 (25%), Positives = 109/264 (41%), Gaps = 14/264 (5%) Query: 17 YRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGAT 76 H+ L K+A +TG GIG IA + G ++ + A+++ A Sbjct: 1 GSHM----SLSGKIAAVTGAAQGIGKAIALRLAKDGADVILLDVKQDTLAETAKEV-EAL 55 Query: 77 GRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDI 136 GRR + L+ D+ + + A K G +DI++N A + P + + + I Sbjct: 56 GRRAVALTADISNRDQFRSTLADAAKTLGGLDIMVNNAGICQVKPILDIEPAEIEKIFSI 115 Query: 137 DTSGTFNVSRVLYEKFF-RDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVE 195 + G + F + G I+N + G+ G L + K AV A+T+ A E Sbjct: 116 NVQGVLWGMQAAATLFKEKGTKGKIINACSIAGHEGYPLLGAYSATKFAVRALTQSAAKE 175 Query: 196 WGPQNIRVNSLAPGPISGTEG------LRRLGGPQ--ASLSTKVTASPLQRLGNKTEIAH 247 I VNS PG + + + G + A+ V L R+ ++A Sbjct: 176 LASSGITVNSYCPGIVGTDMWVTIDKRMAEITGTEIGATYKKYVEGIALGRVETADDVAG 235 Query: 248 SVLYLASPLASYVTGAVLVADGGA 271 V YL+S A Y+TG ++ DGG Sbjct: 236 FVAYLSSSDADYMTGQSVLIDGGL 259 >3RWB-A nrPDB Length = 247 Score = 215 bits (549), Expect = 1e-56, Method: Composition-based stats. Identities = 63/247 (25%), Positives = 103/247 (41%), Gaps = 7/247 (2%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L K A +TG GIG IA G +++ + AA + G++ ++ Sbjct: 4 LAGKTALVTGAAQGIGKAIAARLAADGATVIVSDINAEGAKAAAASI----GKKARAIAA 59 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 D+ P +V A + G IDIL+N A+ + + ++ ++D++ +GTF V+ Sbjct: 60 DISDPGSVKALFAEIQALTGGIDILVNNASIVPFVAWDDVDLDHWRKIIDVNLTGTFIVT 119 Query: 146 RVLYEKFFRDHG-GVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVN 204 R ++ G +++I + G +AK V TR LA E G NI N Sbjct: 120 RAGTDQMRAAGKAGRVISIASNTFFAGTPNMAAYVAAKGGVIGFTRALATELGKYNITAN 179 Query: 205 SLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAV 264 ++ PG I + A ++ G IA V +LAS A ++TG Sbjct: 180 AVTPGLIESDGVKASPHNEAFGFVEMLQA--MKGKGQPEHIADVVSFLASDDARWITGQT 237 Query: 265 LVADGGA 271 L D G Sbjct: 238 LNVDAGM 244 >3D3W-A nrPDB Length = 244 Score = 215 bits (547), Expect = 2e-56, Method: Composition-based stats. Identities = 63/248 (25%), Positives = 109/248 (43%), Gaps = 11/248 (4%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L + +TG G GIG + G V SR+ + + R+ G P+ + Sbjct: 5 LAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIE-----PVCV 59 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 D+ A ++AL G +D+L+N AA L P ++ AF +++ VS Sbjct: 60 DLGDWE----ATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVS 115 Query: 146 RVLYEKFFRDH-GGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVN 204 +++ G IVN+++ R S K A+D +T+ +A+E GP IRVN Sbjct: 116 QIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVN 175 Query: 205 SLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAV 264 ++ P + + G P + T + PL + + +++L+L S + TG+ Sbjct: 176 AVNPTVVMTSMGQATWSDPHKA-KTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGST 234 Query: 265 LVADGGAW 272 L +GG W Sbjct: 235 LPVEGGFW 242 >1UZM-A nrPDB Length = 247 Score = 214 bits (546), Expect = 3e-56, Method: Composition-based stats. Identities = 60/246 (24%), Positives = 103/246 (41%), Gaps = 15/246 (6%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVR 88 + +TGG GIG IA+ G + R + + +DV Sbjct: 16 RSVLVTGGNRGIGLAIAQRLAADGHKVAVTHRGS------------GAPKGLFGVEVDVT 63 Query: 89 APPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVL 148 AV A + G +++L++ A + ++ F+ V++ + +G F V++ Sbjct: 64 DSDAVDRAFTAVEEHQGPVEVLVSNAGLSADAFLMRMTEEKFEKVINANLTGAFRVAQRA 123 Query: 149 YEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAP 208 R+ G ++ I + G G Q + ++KA V M R +A E N+ N +AP Sbjct: 124 SRSMQRNKFGRMIFIGSVSGLWGIGNQANYAASKAGVIGMARSIARELSKANVTANVVAP 183 Query: 209 GPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVAD 268 G I + + P +R+G E+A V +LAS ASY++GAV+ D Sbjct: 184 GYIDTDMTR---ALDERIQQGALQFIPAKRVGTPAEVAGVVSFLASEDASYISGAVIPVD 240 Query: 269 GGAWLT 274 GG + Sbjct: 241 GGMGMG 246 >3UF0-A nrPDB Length = 273 Score = 214 bits (545), Expect = 4e-56, Method: Composition-based stats. Identities = 67/254 (26%), Positives = 105/254 (41%), Gaps = 4/254 (1%) Query: 17 YRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGAT 76 ++ + P L + A +TG GSGIG IA + R G H + R+ + Sbjct: 20 FQSMTGPFSLAGRTAVVTGAGSGIGRAIAHGYARAGAHVLAWGRT--DGVKEVADEIADG 77 Query: 77 GRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDI 136 G + D+ ++ R+D+L+N A PA +S ++ V+ + Sbjct: 78 GGSAEAVVADLADLEGAANVAEELAAT-RRVDVLVNNAGIIARAPAEEVSLGRWREVLTV 136 Query: 137 DTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEW 196 + + +SR G IV I + L +G ++K AV +TR LA EW Sbjct: 137 NLDAAWVLSRSFGTAMLAHGSGRIVTIASMLSFQGGRNVAAYAASKHAVVGLTRALASEW 196 Query: 197 GPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPL 256 + + VN+LAPG + T L + P R ++ ++LAS Sbjct: 197 AGRGVGVNALAPGYVV-TANTAALRADDERAAEITARIPAGRWATPEDMVGPAVFLASDA 255 Query: 257 ASYVTGAVLVADGG 270 ASYV G VL DGG Sbjct: 256 ASYVHGQVLAVDGG 269 >5EJ2-A nrPDB Length = 308 Score = 211 bits (538), Expect = 2e-55, Method: Composition-based stats. Identities = 72/276 (26%), Positives = 117/276 (42%), Gaps = 25/276 (9%) Query: 24 DLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASR-----------SLPRVLTAARKL 72 + KVAFI+G G G A + G + S P L L Sbjct: 33 GRVAGKVAFISGAARGQGRSHAVRLAQEGADIIAIDICGPIENLAYPHSTPEDLAETADL 92 Query: 73 AGATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCP-AGALSFNAFK 131 RR + +DVR A+ +AVD +++ GR+DI++ A + N ++ Sbjct: 93 VKDLDRRIVTAQVDVRDFEALKSAVDSGVEQLGRLDIIVANAGVGTDGRKLHKIRDNVWQ 152 Query: 132 TVMDIDTSGTFNVSRVLYEKFFRD-HGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTR 190 ++DI+ +G ++ + GG IV ++ G + H +AK V + R Sbjct: 153 DMIDINLTGVWHTVKAGVPHVLSGGRGGSIVLTSSVGGRKAYPNTGHYIAAKHGVIGLMR 212 Query: 191 HLAVEWGPQNIRVNSLAPGPISGTEGLR----RLGGPQASLSTKVTASPLQR-------- 238 AVE GP IRVN++ P +S T + RL P +P+ + Sbjct: 213 AFAVELGPHMIRVNAVLPTQVSTTMVMNDQTFRLFRPDLENPGPDDFAPISQMMHTLPVP 272 Query: 239 LGNKTEIAHSVLYLASPLASYVTGAVLVADGGAWLT 274 + ++I+++VL+LAS + YVTG L D G+ L Sbjct: 273 WVDASDISNAVLFLASDESRYVTGVSLPVDAGSLLK 308 >1H5Q-A nrPDB Length = 265 Score = 207 bits (527), Expect = 4e-54, Method: Composition-based stats. Identities = 66/267 (24%), Positives = 104/267 (38%), Gaps = 13/267 (4%) Query: 17 YRHLFCPDLLR--DKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAG 74 H+ + +K +TGG GIG G + + RS + K+ Sbjct: 1 GSHMAPGFTISFVNKTIIVTGGNRGIGLAFTRAVAAAGANVAVIYRSAADAVEVTEKVGK 60 Query: 75 ATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVM 134 G + DV V + Q + G I LI A + + PA L+ F V Sbjct: 61 EFGVKTKAYQCDVSNTDIVTKTIQQIDADLGPISGLIANAGVSVVKPATELTHEDFAFVY 120 Query: 135 DIDTSGTFNVSRVLYEKFF-RDHGGVIVNITATLGNR-------GQALQVHAGSAKAAVD 186 D++ G FN R + + + + G IV ++ G QV S+KAA Sbjct: 121 DVNVFGVFNTCRAVAKLWLQKQQKGSIVVTSSMSSQIINQSSLNGSLTQVFYNSSKAACS 180 Query: 187 AMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIA 246 + + LA EW IRVN+L+PG ++ + + + + PL R E+ Sbjct: 181 NLVKGLAAEWASAGIRVNALSPGYVNTDQTAH---MDKKIRDHQASNIPLNRFAQPEEMT 237 Query: 247 HSVLYLASPLASYVTGAVLVADGGAWL 273 + L S A+Y+TG DGG + Sbjct: 238 GQAILLLSDHATYMTGGEYFIDGGQLI 264 >2HSD-A nrPDB Length = 253 Score = 207 bits (526), Expect = 6e-54, Method: Composition-based stats. Identities = 79/254 (31%), Positives = 110/254 (43%), Gaps = 8/254 (3%) Query: 24 DLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPL 83 + L K ITGG G+G A + G V+A AR+L G Sbjct: 1 NDLSGKTVIITGGARGLGAEAARQAVAAGARVVLADVLDEEGAATAREL----GDAARYQ 56 Query: 84 SMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFN 143 +DV V A +EFG +D L+N A + S F+ V++I+ +G F Sbjct: 57 HLDVTIEEDWQRVVAYAREEFGSVDGLVNNAGISTGMFLETESVERFRKVVEINLTGVFI 116 Query: 144 VSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRV 203 + + GG IVNI++ G G AL G++K V +++ AVE G IRV Sbjct: 117 GMKTVIPAMKDAGGGSIVNISSAAGLMGLALTSSYGASKWGVRGLSKLAAVELGTDRIRV 176 Query: 204 NSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGA 263 NS+ PG +P+ R+G EIA +V+ L S +SYVTGA Sbjct: 177 NSVHPGMTYTPMTAETGIR---QGEGNYPNTPMGRVGEPGEIAGAVVKLLSDTSSYVTGA 233 Query: 264 VLVADGGAWLTFPN 277 L DGG W T P Sbjct: 234 ELAVDGG-WTTGPT 246 >3A28-C nrPDB Length = 258 Score = 207 bits (526), Expect = 7e-54, Method: Composition-based stats. Identities = 65/255 (25%), Positives = 109/255 (42%), Gaps = 12/255 (4%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASR-SLPRVLTAARKLAGATGRRCLPLSMDV 87 KVA +TGG GIG I+E G +A KL A ++ + + +DV Sbjct: 3 KVAMVTGGAQGIGRGISEKLAADGFDIAVADLPQQEEQAAETIKLIEAADQKAVFVGLDV 62 Query: 88 RAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRV 147 +A+D+A ++ G D+L+N A + P ++ K + ++ F + Sbjct: 63 TDKANFDSAIDEAAEKLGGFDVLVNNAGIAQIKPLLEVTEEDLKQIYSVNVFSVFFGIQA 122 Query: 148 LYEKF-FRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSL 206 KF G I+N + +G + + K AV +T+ A E P+ VN+ Sbjct: 123 ASRKFDELGVKGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQAAAQELAPKGHTVNAY 182 Query: 207 APGPISGTEGLRRLGGPQASL---------STKVTASPLQRLGNKTEIAHSVLYLASPLA 257 APG I GT ++ + + ++ L R ++A V +LAS + Sbjct: 183 APG-IVGTGMWEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDVAGLVSFLASENS 241 Query: 258 SYVTGAVLVADGGAW 272 +YVTG V++ DGG Sbjct: 242 NYVTGQVMLVDGGML 256 >5JY1-A nrPDB Length = 274 Score = 204 bits (520), Expect = 3e-53, Method: Composition-based stats. Identities = 75/263 (28%), Positives = 115/263 (43%), Gaps = 8/263 (3%) Query: 24 DLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPL 83 LL +VA +TG G GIG +A F G +IA + +++ G R L + Sbjct: 10 GLLEQRVALVTGAGGGIGRGVARSFGNEGAAVIIAEINESTGRQVEQEIRE-MGGRSLFV 68 Query: 84 SMDVRAPPAVMAAVDQALKEFGRIDILINCAAG-NFLCPAGALSFNAFKTVMDIDTSGTF 142 DV + ++ AAV A+++FG +DIL+N A + + + T+ Sbjct: 69 KTDVTSKASIEAAVRSAVEQFGSLDILVNNAFVPTPNVLLEEKTDEMLEQTLTTSLWATW 128 Query: 143 NVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIR 202 R + G IVN + G L +AKA + +TR A EWG NI Sbjct: 129 WAMRAAFVPMRERRWGRIVNFYSIDTETGAWLHGDYNTAKAGIVGLTRSAASEWGRFNIT 188 Query: 203 VNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKT-EIAHSVLYLASPLASYVT 261 VN++AP + T P+ A PL R G+ +I + ++ AS ++ +VT Sbjct: 189 VNAIAPTAMGATFFELAAKNPE-FAERSAAARPLGRSGDPEQDIGPAAVFFASEMSRFVT 247 Query: 262 GAVLVADGGAWL----TFPNGVK 280 G L DGG L + P G+K Sbjct: 248 GETLHVDGGLHLPGYNSRPAGIK 270 >2P91-A nrPDB Length = 285 Score = 202 bits (515), Expect = 1e-52, Method: Composition-based stats. Identities = 59/256 (23%), Positives = 101/256 (39%), Gaps = 10/256 (3%) Query: 24 DLLRDKVAFITGGG--SGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCL 81 LL K A ITG I + IA+ F R G + P++ R++A G L Sbjct: 17 GLLEGKRALITGVANERSIAYGIAKSFHREGAQLAFTYAT-PKLEKRVREIAKGFGSD-L 74 Query: 82 PLSMDVRAPPAVMAAVDQALKEFGRIDILINCAA----GNFLCPAGALSFNAFKTVMDID 137 + DV + + +G +DI+++ A F S FK MDI Sbjct: 75 VVKCDVSLDEDIKNLKKFLEENWGSLDIIVHSIAYAPKEEFKGGVIDTSREGFKIAMDIS 134 Query: 138 TSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWG 197 ++R L G IV ++ + G AKAA+++ R+LA + Sbjct: 135 VYSLIALTRELLPLM-EGRNGAIVTLSYYGAEKVVPHYNVMGIAKAALESTVRYLAYDIA 193 Query: 198 PQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLA 257 R+N+++ GP+ T + G + +P + ++ + ++L S A Sbjct: 194 KHGHRINAISAGPVK-TLAAYSITGFHLLMEHTTKVNPFGKPITIEDVGDTAVFLCSDWA 252 Query: 258 SYVTGAVLVADGGAWL 273 +TG V+ D G + Sbjct: 253 RAITGEVVHVDNGYHI 268 >3GDF-A nrPDB Length = 267 Score = 201 bits (512), Expect = 2e-52, Method: Composition-based stats. Identities = 66/262 (25%), Positives = 102/262 (38%), Gaps = 9/262 (3%) Query: 16 AYRHLFCPDLLRDKVAFITGGG--SGIGFRIAEIFMRHGCHTVIASRSLPRVLTA-ARKL 72 + L L+ KV +TG G+G A G I S + ++L Sbjct: 8 KHESLLDQLSLKGKVVVVTGASGPKGMGIEAARGCAEMGAAVAITYASRAQGAEENVKEL 67 Query: 73 AGATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKT 132 G + V + + V + +FG+ID I A S A+ Sbjct: 68 EKTYGIKAKAYKCQVDSYESCEKLVKDVVADFGQIDAFIANAGATADSGILDGSVEAWNH 127 Query: 133 VMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQA--LQVHAGSAKAAVDAMTR 190 V+ +D +GTF+ ++ + F G +V + G+ Q AKA M R Sbjct: 128 VVQVDLNGTFHCAKAVGHHFKERGTGSLVITASMSGHIANFPQEQTSYNVAKAGCIHMAR 187 Query: 191 HLAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVL 250 LA EW RVNS++PG I P+ + + P+ R G E+ + + Sbjct: 188 SLANEW-RDFARVNSISPGYIDTGLSDFV---PKETQQLWHSMIPMGRDGLAKELKGAYV 243 Query: 251 YLASPLASYVTGAVLVADGGAW 272 Y AS ++Y TGA L+ DGG Sbjct: 244 YFASDASTYTTGADLLIDGGYT 265 >3V8B-A nrPDB Length = 283 Score = 201 bits (511), Expect = 3e-52, Method: Composition-based stats. Identities = 71/267 (26%), Positives = 112/267 (41%), Gaps = 12/267 (4%) Query: 18 RHLFCPDLLRDK--VAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGA 75 +L+ ++ VA ITG GSGIG A G R+ V A ++ GA Sbjct: 16 ENLYFQSMMNQPSPVALITGAGSGIGRATALALAADGVTVGALGRTRTEVEEVADEIVGA 75 Query: 76 TGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGN-FLCPAGALSFNAFKTVM 134 G + + L DV + AV + +FG +DI++ A N P L + + Sbjct: 76 -GGQAIALEADVSDELQMRNAVRDLVLKFGHLDIVVANAGINGVWAPIDDLKPFEWDETI 134 Query: 135 DIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQ--ALQVHAGSAKAAVDAMTRHL 192 ++ GTF + + GG IV +++ G R + KAA A+ + L Sbjct: 135 AVNLRGTFLTLHLTVPYLKQRGGGAIVVVSSINGTRTFTTPGATAYTATKAAQVAIVQQL 194 Query: 193 AVEWGPQNIRVNSLAPGPISG----TEGLRRLGGPQASLSTKVTASPL--QRLGNKTEIA 246 A+E G +IRVN++ PG I LR + P+ + G ++A Sbjct: 195 ALELGKHHIRVNAVCPGAIETNISDNTKLRHEEETAIPVEWPKGQVPITDGQPGRSEDVA 254 Query: 247 HSVLYLASPLASYVTGAVLVADGGAWL 273 + +L S A +VTG+ + DGG L Sbjct: 255 ELIRFLVSERARHVTGSPVWIDGGQGL 281 >4AVY-A nrPDB Length = 242 Score = 200 bits (510), Expect = 5e-52, Method: Composition-based stats. Identities = 69/253 (27%), Positives = 106/253 (41%), Gaps = 15/253 (5%) Query: 20 LFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRR 79 +F D+ + +TGG SGIG IA F G V V R Sbjct: 3 VFQHDIYAGQQVLVTGGSSGIGAAIAMQFAELGAEVVALGLDADGVHA-------PRHPR 55 Query: 80 CLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTS 139 +D+ + + R+D+L+N A + F+ V+ ++ S Sbjct: 56 IRREELDITDSQRLQRLFEALP----RLDVLVNNAGISRD--REEYDLATFERVLRLNLS 109 Query: 140 GTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQ 199 S++ GG I+NI + G A + ++K A+ +TR LA E+ + Sbjct: 110 AAMLASQLA-RPLLAQRGGSILNIASMYSTFGSADRPAYSASKGAIVQLTRSLACEYAAE 168 Query: 200 NIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASY 259 IRVN++APG I G +A+ + +PL R G E+A + +L P AS+ Sbjct: 169 RIRVNAIAPGWIDTPLGAGLKADVEATR-RIMQRTPLARWGEAPEVASAAAFLCGPGASF 227 Query: 260 VTGAVLVADGGAW 272 VTGAVL DGG Sbjct: 228 VTGAVLAVDGGYL 240 >5O3Z-A nrPDB Length = 263 Score = 200 bits (509), Expect = 5e-52, Method: Composition-based stats. Identities = 60/256 (23%), Positives = 99/256 (38%), Gaps = 11/256 (4%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATG-RRCLPLSMDV 87 +VA + GGG +G + E + G H +A + A + G R +D Sbjct: 7 QVAVVIGGGQTLGAFLCEGLAQAGYHVAVADLNESNANRLADTINSRYGAGRAYGFKVDA 66 Query: 88 RAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRV 147 +V A + FGR D+L+ A P F + ++ G F SR Sbjct: 67 TDEASVEALARAVDETFGRADLLVYSAGVAKAAPITQFRLTDFDLSLQVNLVGYFLCSRE 126 Query: 148 LYEKFFRDH-GGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSL 206 + RD G I+ I + G G +AK +T+ LA++ I V+SL Sbjct: 127 FSKLMIRDGIKGRIIQINSKSGKVGSKHNSGYSAAKFGGVGLTQSLALDLAEYGITVHSL 186 Query: 207 APGPISGTEGLRRL---------GGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLA 257 G + + + L P+ V PL+R + ++ + +L+ AS A Sbjct: 187 MLGNLLKSPMFQSLLPQYAEKLGITPEEVEPYYVDKVPLKRGCDYQDVLNVLLFYASDKA 246 Query: 258 SYVTGAVLVADGGAWL 273 +Y TG + GG + Sbjct: 247 AYCTGQSINVTGGQVM 262 >3UN1-A nrPDB Length = 260 Score = 200 bits (508), Expect = 8e-52, Method: Composition-based stats. Identities = 65/258 (25%), Positives = 118/258 (45%), Gaps = 22/258 (8%) Query: 18 RHLFCPDLLRD--KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGA 75 +L+ ++R+ KV ITG GIG + + V SRS + + Sbjct: 16 ENLYFQSMMRNQQKVVVITGASQGIGAGLVRAYRDRNYRVVATSRS----------IKPS 65 Query: 76 TGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMD 135 ++ D+ P V + ++ FGRID L+N A P ++ + + Sbjct: 66 ADPDIHTVAGDISKPETADRIVREGIERFGRIDSLVNNAGVFLAKPFVEMTQEDYDHNLG 125 Query: 136 IDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSA--KAAVDAMTRHLA 193 ++ +G F++++ + + G IV+IT +L ++ A ++ K ++A+TR LA Sbjct: 126 VNVAGFFHITQRAAAEMLKQGSGHIVSITTSLVDQPMVGMPSALASLTKGGLNAVTRSLA 185 Query: 194 VEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLA 253 +E+ +RVN+++PG I P + ST P+ R+G ++ +VLYL Sbjct: 186 MEFSRSGVRVNAVSPGVIKTPM------HPAETHSTLAGLHPVGRMGEIRDVVDAVLYL- 238 Query: 254 SPLASYVTGAVLVADGGA 271 A ++TG +L DGG Sbjct: 239 -EHAGFITGEILHVDGGQ 255 >1O5I-A nrPDB Length = 249 Score = 199 bits (506), Expect = 1e-51, Method: Composition-based stats. Identities = 63/250 (25%), Positives = 97/250 (38%), Gaps = 19/250 (7%) Query: 27 RDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMD 86 RDK + GIG +A++ + G I +R+ +L +G R + D Sbjct: 18 RDKGVLVLAASRGIGRAVADVLSQEGAEVTICARN--------EELLKRSGHR--YVVCD 67 Query: 87 VRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSR 146 +R +D ++ +DIL+ A G L+ FK +D + R Sbjct: 68 LRKD------LDLLFEKVKEVDILVLNAGGPKAGFFDELTNEDFKEAIDSLFLNMIKIVR 121 Query: 147 VLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSL 206 G IV IT+ + SA+ A+ + L+ E P I VN + Sbjct: 122 NYLPAMKEKGWGRIVAITSFSVISPIENLYTSNSARMALTGFLKTLSFEVAPYGITVNCV 181 Query: 207 APGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLV 266 APG L + + P++R+ EIA V +L S ASY+TG +V Sbjct: 182 APGWTETERVKELLS--EEKKKQVESQIPMRRMAKPEEIASVVAFLCSEKASYLTGQTIV 239 Query: 267 ADGGAWLTFP 276 DGG FP Sbjct: 240 VDGGLS-KFP 248 >2FWM-X nrPDB Length = 250 Score = 198 bits (505), Expect = 1e-51, Method: Composition-based stats. Identities = 62/257 (24%), Positives = 109/257 (42%), Gaps = 20/257 (7%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 K ++TG G GIG+ A F+ G ++ + M Sbjct: 5 FSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEV-----------M 53 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 DV V + L E R+D L+N A + LS ++ ++ G FN+ Sbjct: 54 DVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLF 113 Query: 146 RVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNS 205 + +F R GG IV + + + + G++KAA+ ++ + +E +R N Sbjct: 114 QQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNV 173 Query: 206 LAPGPISGTEGLRRLGGPQASLSTKV--------TASPLQRLGNKTEIAHSVLYLASPLA 257 ++PG + T+ R L + ++ PL ++ EIA+++L+LAS LA Sbjct: 174 VSPGS-TDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLA 232 Query: 258 SYVTGAVLVADGGAWLT 274 S++T +V DGG+ L Sbjct: 233 SHITLQDIVVDGGSTLG 249 >3U4C-A nrPDB Length = 281 Score = 198 bits (504), Expect = 2e-51, Method: Composition-based stats. Identities = 62/268 (23%), Positives = 102/268 (38%), Gaps = 15/268 (5%) Query: 14 LPAYRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARK-L 72 +P H+ + AF+ G GIG IA VI SR+L + + L Sbjct: 15 VPRGSHM------SKRTAFVMGASQGIGKAIALKLADQHFSLVINSRNLDNIESVKEDIL 68 Query: 73 AGATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKT 132 A + L+ D+ + + GR+D+LIN G + Sbjct: 69 AKHPEASVIVLAGDMSDQHTRAGIFQKIESQCGRLDVLINNIPGGAPDTFDNCNIEDMTA 128 Query: 133 VMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHL 192 T + + ++ G I+NI L A AA+ ++++ Sbjct: 129 TFTQKTVAYIDAIKRASSLMKQNEFGRIINIVGNLWKEPGANMFTNSMMNAALINASKNI 188 Query: 193 AVEWGPQNIRVNSLAPGPISGTE--------GLRRLGGPQASLSTKVTASPLQRLGNKTE 244 +++ P NI VN L PG I+ + Q + + P++R+G+ E Sbjct: 189 SIQLAPHNITVNCLNPGFIATDRYHQFVENVMKKNSISKQKAEEQIASGIPMKRVGSAEE 248 Query: 245 IAHSVLYLASPLASYVTGAVLVADGGAW 272 A +LAS ASY+TG + ADGG+ Sbjct: 249 TAALAAFLASEEASYITGQQISADGGSM 276 >1CYD-A nrPDB Length = 244 Score = 197 bits (501), Expect = 4e-51, Method: Composition-based stats. Identities = 58/243 (23%), Positives = 111/243 (45%), Gaps = 11/243 (4%) Query: 31 AFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAP 90 A +TG G GIG + G V +R+ +++ A++ G P+ +D+ Sbjct: 10 ALVTGAGKGIGRDTVKALHASGAKVVAVTRTNSDLVSLAKECPGIE-----PVCVDLGDW 64 Query: 91 PAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVLYE 150 A ++AL G +D+L+N AA + P ++ AF ++ F VS+++ Sbjct: 65 D----ATEKALGGIGPVDLLVNNAALVIMQPFLEVTKEAFDRSFSVNLRSVFQVSQMVAR 120 Query: 151 KFFRDH-GGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPG 209 G IVN+++ + + + S K A+ +T+ +A+E GP IRVNS+ P Sbjct: 121 DMINRGVPGSIVNVSSMVAHVTFPNLITYSSTKGAMTMLTKAMAMELGPHKIRVNSVNPT 180 Query: 210 PISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVADG 269 + G + P+ + PL++ ++ +S+L+L S ++ +G ++ D Sbjct: 181 VVLTDMGKKVSADPEFARK-LKERHPLRKFAEVEDVVNSILFLLSDRSASTSGGGILVDA 239 Query: 270 GAW 272 G Sbjct: 240 GYL 242 >1HXH-A nrPDB Length = 253 Score = 196 bits (499), Expect = 9e-51, Method: Composition-based stats. Identities = 65/251 (25%), Positives = 106/251 (42%), Gaps = 13/251 (5%) Query: 24 DLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPL 83 + L+ KVA +TGG SG+G + ++ + G + + A ++LA G R + + Sbjct: 2 NRLQGKVALVTGGASGVGLEVVKLLLGEGAKVAFSDIN----EAAGQQLAAELGERSMFV 57 Query: 84 SMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFN 143 DV + + + G +++L+N A F ++ I+T F Sbjct: 58 RHDVSSEADWTLVMAAVQRRLGTLNVLVNNAGILLPGDMETGRLEDFSRLLKINTESVFI 117 Query: 144 VSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQN--I 201 + ++ GG I+N+ + ++KAAV A+TR A+ Q I Sbjct: 118 GCQQGIAAM-KETGGSIINMASVSSWLPIEQYAGYSASKAAVSALTRAAALSCRKQGYAI 176 Query: 202 RVNSLAPGPISGTEGLRRLGGPQASLSTKVTASP-LQRLGN---KTEIAHSVLYLASPLA 257 RVNS+ P I L P+ V P L R G IA VL+LAS + Sbjct: 177 RVNSIHPDGIYTPMMQASL--PKGVSKEMVLHDPKLNRAGRAYMPERIAQLVLFLASDES 234 Query: 258 SYVTGAVLVAD 268 S ++G+ L AD Sbjct: 235 SVMSGSELHAD 245 >5JS6-A nrPDB Length = 274 Score = 195 bits (496), Expect = 2e-50, Method: Composition-based stats. Identities = 63/235 (26%), Positives = 114/235 (48%), Gaps = 11/235 (4%) Query: 45 AEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAPPAVMAAVDQALKEF 104 F+ G VI + ++L G + + DV V V + ++ F Sbjct: 28 VRAFVNSGARVVICDKDESGGRALEQELPG-----AVFILCDVTQEDDVKTLVSETIRRF 82 Query: 105 GRIDILINCAAGNFL-CPAGALSFNAFKTVMDIDTSGTFNVSRVLYEKFFRDHGGVIVNI 163 GR+D ++N A + S F+ +++++ GT+ ++++ + G ++NI Sbjct: 83 GRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQ-GNVINI 141 Query: 164 TATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGT---EGLRRL 220 ++ +G GQA V + K AV AMT+ LA++ P +RVN ++PG I E + Sbjct: 142 SSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALM 201 Query: 221 GGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVADGGAWLTF 275 P+A++ + A PL R+G E+ + ++LAS A++ TG L+ GGA L + Sbjct: 202 PDPRATIREGMLAQPLGRMGQPAEVGAAAVFLAS-EANFCTGIELLVTGGAELGY 255 >4TRR-A nrPDB Length = 269 Score = 195 bits (495), Expect = 2e-50, Method: Composition-based stats. Identities = 58/258 (22%), Positives = 112/258 (43%), Gaps = 11/258 (4%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L K A +TG SGIG IA + G IA + A ++ A G + + ++M Sbjct: 12 LNGKTAVVTGAASGIGKEIALELAKAGAAVAIADLNQDGANAVADEINKA-GGKAIGVAM 70 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 DV AV +D+ + FG +DIL++ A + P SF +K + I G F + Sbjct: 71 DVTNEEAVNTGIDKVAEAFGSVDILVSNAGIQIVNPIENYSFADWKKMQAIHVDGAFLTT 130 Query: 146 RVLYEKFFR-DHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVN 204 + + ++ D GGV++ + + + L+ +AK + + R LA E N+R + Sbjct: 131 KAALKHMYKDDRGGVVIYMGSVHSHEASPLKSAYVTAKHGLLGLARVLAKEGAKHNVRSH 190 Query: 205 SLAPGPISGTEGLRRLG---------GPQASLSTKVTASPLQRLGNKTEIAHSVLYLASP 255 + PG + +++ + + + ++A +VL+L++ Sbjct: 191 VVCPGFVRTPLVDKQIPEQAKELGISEEEVIKKVMLGNTVDGVFTTVQDVAQTVLFLSAF 250 Query: 256 LASYVTGAVLVADGGAWL 273 ++ +TG + G ++ Sbjct: 251 PSAALTGQSFIVSHGWFM 268 >2AG5-A nrPDB Length = 246 Score = 195 bits (495), Expect = 2e-50, Method: Composition-based stats. Identities = 58/255 (22%), Positives = 102/255 (40%), Gaps = 14/255 (5%) Query: 24 DLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPL 83 L KV +T GIG A F R G + + ++ ++L G + L Sbjct: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKL----QELEKYPGIQTRVL 57 Query: 84 SMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFN 143 DV + ++ R+D+L N A + M+++ + Sbjct: 58 --DVTKKKQIDQFANEVE----RLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYL 111 Query: 144 VSRVLYEKFFRDHGGVIVNITATLG-NRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIR 202 + + K G I+N+++ +G + + KAAV +T+ +A ++ Q IR Sbjct: 112 MIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIR 171 Query: 203 VNSLAPGPISGTEGLRRL---GGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASY 259 N + PG + R+ G P+ + + + R EIA +YLAS ++Y Sbjct: 172 CNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAY 231 Query: 260 VTGAVLVADGGAWLT 274 VTG ++ DGG L Sbjct: 232 VTGNPVIIDGGWSLG 246 >4EGF-A nrPDB Length = 266 Score = 194 bits (493), Expect = 4e-50, Method: Composition-based stats. Identities = 66/250 (26%), Positives = 109/250 (43%), Gaps = 2/250 (0%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L K A ITG GIG IA F G V++ R + + A R L G +++ Sbjct: 18 LDGKRALITGATKGIGADIARAFAAAGARLVLSGRDVSELDAARRALGEQFGTDVHTVAI 77 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 D+ P A +A + FG +D+L+N A + P F + ++ ++ Sbjct: 78 DLAEPDAPAELARRAAEAFGGLDVLVNNAGISHPQPVVDTDPQLFDATIAVNLRAPALLA 137 Query: 146 RVLYEKFFRDH-GGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVN 204 + + GG I+ + + ++KA + T+ LA E GP IR N Sbjct: 138 SAVGKAMVAAGEGGAIITVASAAALAPLPDHYAYCTSKAGLVMATKVLARELGPHGIRAN 197 Query: 205 SLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAV 264 S+ P + TE +R+ G +A + + PL R E++ +V++LAS AS + G Sbjct: 198 SVCPTVVL-TEMGQRVWGDEAKSAPMIARIPLGRFAVPHEVSDAVVWLASDAASMINGVD 256 Query: 265 LVADGGAWLT 274 + DGG + Sbjct: 257 IPVDGGYTMG 266 >4ALL-A nrPDB Length = 277 Score = 188 bits (479), Expect = 2e-48, Method: Composition-based stats. Identities = 69/260 (26%), Positives = 113/260 (43%), Gaps = 8/260 (3%) Query: 17 YRHLFCPDLLRDKVAFITGGG--SGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAG 74 RH+ L +K I G I F +A++ + G V R + L Sbjct: 19 GRHMLN---LENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQ 75 Query: 75 ATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRID-ILINCAAGNFLCPAGALSFNAFKTV 133 +DV++ V+ +Q K+ G ID + + A N G S + + Sbjct: 76 LNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGF 135 Query: 134 MDIDTSGTFNVSRVLYE-KFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHL 192 + +++++ V +E K GG IV T G G AKA+++A ++L Sbjct: 136 LLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYL 195 Query: 193 AVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYL 252 A++ GP NIRVN+++ GPI T + +GG L +PL+R ++ E+ + YL Sbjct: 196 ALDLGPDNIRVNAISAGPIR-TLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYL 254 Query: 253 ASPLASYVTGAVLVADGGAW 272 S L+S VTG + D G Sbjct: 255 LSDLSSGVTGENIHVDSGFH 274 >2X9N-A nrPDB Length = 288 Score = 187 bits (476), Expect = 4e-48, Method: Composition-based stats. Identities = 60/286 (20%), Positives = 104/286 (36%), Gaps = 41/286 (14%) Query: 14 LPAYRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVL-TAARKL 72 +P H+ P A +TG IG IA + G VI + + A +L Sbjct: 15 VPRGSHMEAPA------AVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADEL 68 Query: 73 AGATGRRCLPLSMDVRA----PPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFN 128 + D+ P + ++ + FGR D+L+N A+ + P Sbjct: 69 NKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGDHE 128 Query: 129 A----------FKTVMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITAT----------LG 168 ++ + F ++ F + G N T++ + Sbjct: 129 DNSNGKTVETQVAELIGTNAIAPFLLT----MSFAQRQKGTNPNCTSSNLSIVNLCDAMV 184 Query: 169 NRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLS 228 ++ K A+ +T+ A+E P IRVN +APG L + + Sbjct: 185 DQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGV-----SLLPVAMGEEEKD 239 Query: 229 TKVTASPLQRL-GNKTEIAHSVLYLASPLASYVTGAVLVADGGAWL 273 PL R + +IA +V++L S A Y+TG+++ DGG L Sbjct: 240 KWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSL 285 >2YW9-A nrPDB Length = 261 Score = 187 bits (474), Expect = 6e-48, Method: Composition-based stats. Identities = 67/254 (26%), Positives = 104/254 (40%), Gaps = 11/254 (4%) Query: 26 LRDKVAFITGGG--SGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPL 83 L K A + G +GF IA G ++ + R+ A KLA A G L Sbjct: 6 LSGKKALVMGVTNQRSLGFAIAAKLKEAGAEVALSYQ-AERLRPEAEKLAEALGG-ALLF 63 Query: 84 SMDVRAPPAVMAAVDQALKEFGRIDILINCAA----GNFLCPAGALSFNAFKTVMDIDTS 139 DV + A + FG +D L++ A + +++ Sbjct: 64 RADVTQDEELDALFAGVKEAFGGLDYLVHAIAFAPREAMEGRYIDTRRQDWLLALEVSAY 123 Query: 140 GTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQ 199 V+R GG IV +T + AKAA++A R+LA E GP+ Sbjct: 124 SLVAVARRAEPLL--REGGGIVTLTYYASEKVVPKYNVMAIAKAALEASVRYLAYELGPK 181 Query: 200 NIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASY 259 +RVN+++ GP+ T R + G +PL+R + E+ + L+L SPLAS Sbjct: 182 GVRVNAISAGPVR-TVAARSIPGFTKMYDRVAQTAPLRRNITQEEVGNLGLFLLSPLASG 240 Query: 260 VTGAVLVADGGAWL 273 +TG V+ D G + Sbjct: 241 ITGEVVYVDAGYHI 254 >4RGB-A nrPDB Length = 294 Score = 187 bits (474), Expect = 7e-48, Method: Composition-based stats. Identities = 60/273 (21%), Positives = 101/273 (36%), Gaps = 22/273 (8%) Query: 21 FCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLP-----------RVLTAA 69 + L +V FITG G G A + G + V L Sbjct: 18 YGMGSLDGRVVFITGAARGQGRSHAVMCAEQGANIVGVDICEDIDIVPYKLGTYEELEET 77 Query: 70 RKLAGATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNA 129 +L TG+ L DVR + D +++FG ID +I A P + A Sbjct: 78 ARLVEKTGQEMLFRKADVRDKAVLQEVFDAGVEQFGHIDTVIANAGVVLTNPDERDASEA 137 Query: 130 FKTVMDIDTSGTFNVSRVLYEKFF-RDHGGVIVNITATLGNR----GQALQVHAGSAKAA 184 + +DI G +N +V R GG ++ ++ + G+ ++K A Sbjct: 138 LRLGLDIMLIGVWNTFQVAIPHMKERGQGGNLIATSSMIALLDLTDGRGGTDAYLTSKLA 197 Query: 185 VDAMTRHLAVEWGPQNIRVNSLAPGPISGTE------GLRRLGGPQASLSTKVTASPLQR 238 + + R A+ IRVN +AP S + + ++ TA P Sbjct: 198 ITGLVRSYALMLAADRIRVNGVAPTNCSTPMITENPALFKVIEENPHLVNAMSTALPDFP 257 Query: 239 LGNKTEIAHSVLYLASPLASYVTGAVLVADGGA 271 + ++++++L+L S TG+VL D G Sbjct: 258 MIEPRDVSNAILFLISDAGRSFTGSVLKVDAGM 290 >5YCX-A nrPDB Length = 266 Score = 185 bits (469), Expect = 2e-47, Method: Composition-based stats. Identities = 66/255 (25%), Positives = 107/255 (41%), Gaps = 7/255 (2%) Query: 24 DLLRDKVAFITGGG--SGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGA-TGRRC 80 +LL+ K + G I + IA G + R+ R+LA G+ Sbjct: 4 ELLQGKTFVVMGVANQRSIAWGIARSLHNAGAKLIFTYAG-ERLERNVRELADTLEGQES 62 Query: 81 LPLSMDVRAPPAVMAAVDQALKEFGRIDILINC-AAGNFLCPAGALSFNAFKTVMDIDTS 139 L L DV + A + +E G I + +C A N G + + Sbjct: 63 LVLPCDVTNDEELTACFETIKQEVGTIHGVAHCIAFANRDDLKGEFVDTSRDGFLLAQNI 122 Query: 140 GTFNVSRVLYE-KFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGP 198 F+++ V E K GG I+ +T G R G AKA+++A ++LA + G Sbjct: 123 SAFSLTAVAREAKKVMTEGGNILTLTYLGGERVVKNYNVMGVAKASLEASVKYLANDLGQ 182 Query: 199 QNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLAS 258 IRVN+++ GPI T + +G + L +PL+R + E+ + ++L S LA Sbjct: 183 HGIRVNAISAGPIR-TLSAKGVGDFNSILREIEERAPLRRTTTQEEVGDTAVFLFSDLAR 241 Query: 259 YVTGAVLVADGGAWL 273 VTG + D G + Sbjct: 242 GVTGENIHVDSGYHI 256 >5TF4-A nrPDB Length = 274 Score = 183 bits (464), Expect = 8e-47, Method: Composition-based stats. Identities = 66/269 (24%), Positives = 106/269 (39%), Gaps = 12/269 (4%) Query: 24 DLLRDKVAFITG--GGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCL 81 LL K I G I + IA+ G + G C Sbjct: 8 GLLYGKRGLILGLANNRSIAWGIAKTASSAGAELAFTYQGEAMKKRVEPLAEEVKGFVCG 67 Query: 82 PLSMDVRAPPAVMAAVDQALKEFGRIDILINCAA----GNFLCPAGALSFNAFKTVMDID 137 DV ++ A + K++G++D L++ +S + F M+I Sbjct: 68 --HCDVSDSASIDAVFNTIEKKWGKLDFLVHAIGFSDKEELSGRYVDISESNFMMTMNIS 125 Query: 138 TSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWG 197 +++ + GG I+ +T + G AKAA++A ++LAV+ G Sbjct: 126 VYSLTALTKRAEKLM--SDGGSILTLTYYGAEKVVPNYNVMGVAKAALEASVKYLAVDLG 183 Query: 198 PQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLA 257 P++IRVN+++ GPI T +G + L +PL+R E+ S LYL S L+ Sbjct: 184 PKHIRVNAISAGPIK-TLAASGIGDFRYILKWNEYNAPLRRTVTIEEVGDSALYLLSDLS 242 Query: 258 SYVTGAVLVADGGAWLTFPNGVKGLPDFA 286 VTG V D G + V PD + Sbjct: 243 RSVTGEVHHVDSGYNIIGMKAVDA-PDIS 270 >2BGM-A nrPDB Length = 278 Score = 182 bits (463), Expect = 1e-46, Method: Composition-based stats. Identities = 61/244 (25%), Positives = 93/244 (38%), Gaps = 10/244 (4%) Query: 45 AEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAPPAVMAAVDQALKEF 104 A++F+R+G VIA + + + + DV V VD + + Sbjct: 33 AKLFVRYGAKVVIADIADDHGQKVCNNI--GSPDVISFVHCDVTKDEDVRNLVDTTIAKH 90 Query: 105 GRIDILINCAAGNFLCPAGALS--FNAFKTVMDIDTSGTFNVSRVLYEKFFRDHGGVIVN 162 G++DI+ P L FK VMDI+ G F V++ G IV Sbjct: 91 GKLDIMFGNVGVLSTTPYSILEAGNEDFKRVMDINVYGAFLVAKHAARVMIPAKKGSIVF 150 Query: 163 ITATLGNRGQALQVH-AGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRLG 221 + H + K AV +T L E G IRVN ++P ++ G Sbjct: 151 TASISSFTAGEGVSHVYTATKHAVLGLTTSLCTELGEYGIRVNCVSPYIVASPLLTDVFG 210 Query: 222 GPQASLSTKVTASP--LQRLGNKTEIAHSVLYLASPLASYVTGAVLVADGGAWLT---FP 276 + + + L ++A +V YLA + YV+G LV DGG T FP Sbjct: 211 VDSSRVEELAHQAANLKGTLLRAEDVADAVAYLAGDESKYVSGLNLVIDGGYTRTNPAFP 270 Query: 277 NGVK 280 +K Sbjct: 271 TALK 274 >3OIG-A nrPDB Length = 266 Score = 180 bits (458), Expect = 4e-46, Method: Composition-based stats. Identities = 59/258 (22%), Positives = 99/258 (38%), Gaps = 11/258 (4%) Query: 24 DLLRDKVAFITGGG--SGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRR-C 80 L + + G I + IA G + R+ + +LAG R Sbjct: 3 FSLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAG-ERLEKSVHELAGTLDRNDS 61 Query: 81 LPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAA----GNFLCPAGALSFNAFKTVMDI 136 + L DV + ++ G I + +C A + + + F +I Sbjct: 62 IILPCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLLAHNI 121 Query: 137 DTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEW 196 + V + GG IV +T G G AKA++DA ++LA + Sbjct: 122 SSYSLTAVVKAARPMM--TEGGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAADL 179 Query: 197 GPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPL 256 G +NIRVNS++ GPI T + + + L +PL+R E+ + +L S + Sbjct: 180 GKENIRVNSISAGPIR-TLSAKGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLFSDM 238 Query: 257 ASYVTGAVLVADGGAWLT 274 + +TG L D G +T Sbjct: 239 SRGITGENLHVDSGFHIT 256 >3RKU-A nrPDB Length = 287 Score = 180 bits (458), Expect = 5e-46, Method: Composition-based stats. Identities = 56/263 (21%), Positives = 103/263 (39%), Gaps = 14/263 (5%) Query: 14 LPAYRHLFCP----DLLRDKVAFITGGGSGIGFRIAEIFMRHG---CHTVIASRSLPRVL 66 +P H+ + L K ITG +GIG A ++ ++A+R L ++ Sbjct: 15 VPRGSHMSQGRKAAERLAKKTVLITGASAGIGKATALEYLEASNGDMKLILAARRLEKLE 74 Query: 67 TAARKLAGAT-GRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFL-CPAGA 124 + + + +D+ + ++ +EF IDIL+N A G Sbjct: 75 ELKKTIDQEFPNAKVHVAQLDITQAEKIKPFIENLPQEFKDIDILVNNAGKALGSDRVGQ 134 Query: 125 LSFNAFKTVMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAA 184 ++ + V D + + N+++ + F + G IVN+ + G ++K A Sbjct: 135 IATEDIQDVFDTNVTALINITQAVLPIFQAKNSGDIVNLGSIAGRDAYPTGSIYCASKFA 194 Query: 185 VDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRL-GGPQASLSTKVTASPLQRLGNKT 243 V A T L E IRV +APG + L R G + + + +PL Sbjct: 195 VGAFTDSLRKELINTKIRVILIAPGLVETEFSLVRYRGNEEQAKNVYKDTTPLM----AD 250 Query: 244 EIAHSVLYLASPLASYVTGAVLV 266 ++A ++Y S + V L+ Sbjct: 251 DVADLIVYATSRKQNTVIADTLI 273 >5IZ4-A nrPDB Length = 271 Score = 180 bits (458), Expect = 5e-46, Method: Composition-based stats. Identities = 73/257 (28%), Positives = 104/257 (40%), Gaps = 13/257 (5%) Query: 30 VAFITGGGSGIGFRIAEIFMRHGCHTVIA--SRSLPRVLTAARKLAGATGRRCLPLSMDV 87 V ITG SGIG A F + G I S + L G + L DV Sbjct: 16 VCVITGSASGIGAATALRFAQAGWSVAIGNFDDSTRDAASTVEALCRDAGAQTLIFDADV 75 Query: 88 RAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNA---FKTVMDIDTSGTFNV 144 AVD + RID LINCA + P A F+ V ++ G + + Sbjct: 76 GKDADCRHAVDMVASRWQRIDALINCAGTTRVIPHNAFDQIDDFEFERVYRVNLIGLYQM 135 Query: 145 SRVLYEKFFRD----HGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQN 200 +R +VN+++ G G + ++K AV+ +T LA P Sbjct: 136 TRAAVPLLRESASATRSTSVVNVSSLAGLNGTGSSIAYAASKGAVNTLTLSLARNLAPH- 194 Query: 201 IRVNSLAPGPISGTEGLRRLGGP--QASLSTKVTASPLQRLGNKTEIAHSVLYLASPLAS 258 IRVN+LAPG + LR L LS ++PL+R+ EIA +L + A Sbjct: 195 IRVNALAPGMVDDGLLLRVLDAAAYDGVLSRMTESAPLKRVSRPAEIAELAWFLTA-HAP 253 Query: 259 YVTGAVLVADGGAWLTF 275 +TG V+ A+ G L Sbjct: 254 AITGQVIAAENGLLLGG 270 >3GRK-A nrPDB Length = 293 Score = 179 bits (455), Expect = 1e-45, Method: Composition-based stats. Identities = 71/271 (26%), Positives = 105/271 (38%), Gaps = 12/271 (4%) Query: 22 CPDLLRDKVAFITG--GGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRR 79 LL+ K I G I + IA+ G + + LA G Sbjct: 25 QSGLLQGKRGLILGVANNRSIAWGIAKAAREAGAELAFTYQG-DALKKRVEPLAEELGAF 83 Query: 80 CLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAA----GNFLCPAGALSFNAFKTVMD 135 DV ++ A + K++G++D L++ S F M Sbjct: 84 VAGH-CDVADAASIDAVFETLEKKWGKLDFLVHAIGFSDKDELTGRYIDTSEANFTNTML 142 Query: 136 IDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVE 195 I VSR + GG I+ +T + G AKAA++A ++LAV+ Sbjct: 143 ISVYSLTAVSRRAEKLMA--DGGSILTLTYYGAEKVMPNYNVMGVAKAALEASVKYLAVD 200 Query: 196 WGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASP 255 GPQNIRVN+++ GPI T +G + L +PL+R E+ LY S Sbjct: 201 LGPQNIRVNAISAGPIK-TLAASGIGDFRYILKWNEYNAPLRRTVTIDEVGDVGLYFLSD 259 Query: 256 LASYVTGAVLVADGGAWLTFPNGVKGLPDFA 286 L+ VTG V AD G + V PD + Sbjct: 260 LSRSVTGEVHHADSGYHVIGMKAVDA-PDIS 289 >4ZJU-A nrPDB Length = 275 Score = 178 bits (453), Expect = 2e-45, Method: Composition-based stats. Identities = 60/258 (23%), Positives = 99/258 (38%), Gaps = 11/258 (4%) Query: 21 FCPDLLRDKVAFITGGGS--GIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGR 78 LL K I G S I + IA+ R G + ++ + A G Sbjct: 9 MTQGLLAGKRFLIAGVASKLSIAYGIAQALHREGAELAFTYPN-EKLKKRVDEFAEQFGS 67 Query: 79 RCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAG-----ALSFNAFKTV 133 + L DV + A + K + +D +++ + FK Sbjct: 68 K-LVFPCDVAVDAEIDNAFAELAKHWDGVDGVVHSIGFAPAHTLDGDFTDVTDRDGFKIA 126 Query: 134 MDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLA 193 DI ++R + + G ++ +T R G AKA+++A R+LA Sbjct: 127 HDISAYSFVAMARAA-KPLLQARQGCLLTLTYQGSERVMPNYNVMGMAKASLEAGVRYLA 185 Query: 194 VEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLA 253 G IRVN+++ GPI T + + L +PL+R E+ ++ L+L Sbjct: 186 SSLGVDGIRVNAISAGPIR-TLAASGIKSFRKMLDANEKVAPLKRNVTIEEVGNAALFLC 244 Query: 254 SPLASYVTGAVLVADGGA 271 SP AS +TG +L D G Sbjct: 245 SPWASGITGEILYVDAGF 262 >4DA9-A nrPDB Length = 280 Score = 178 bits (452), Expect = 2e-45, Method: Composition-based stats. Identities = 64/266 (24%), Positives = 105/266 (39%), Gaps = 10/266 (3%) Query: 18 RHLFCPDLLRDK---VAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAG 74 +L+ ++ K VA +TGG GIG IA G I + Sbjct: 16 ENLYFQSMMTQKARPVAIVTGGRRGIGLGIARALAASGFDIAITGIGDAEGVAPVIAELS 75 Query: 75 ATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCP--AGALSFNAFKT 132 G R + L D+ + A VD + EFGRID L+N A + L F T Sbjct: 76 GLGARVIFLRADLADLSSHQATVDAVVAEFGRIDCLVNNAGIASIVRDDFLDLKPENFDT 135 Query: 133 VMDIDTSGTFNVSRVLYEKFF---RDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMT 189 ++ ++ GT ++ + + I+NIT+ ++ +KA + A + Sbjct: 136 IVGVNLRGTVFFTQAVLKAMLASDARASRSIINITSVSAVMTSPERLDYCMSKAGLAAFS 195 Query: 190 RHLAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSV 249 + LA+ I V + PG I G + + + P++R G +I + V Sbjct: 196 QGLALRLAETGIAVFEVRPGIIRSDMTAAVSGKYDGLIESGL--VPMRRWGEPEDIGNIV 253 Query: 250 LYLASPLASYVTGAVLVADGGAWLTF 275 LA + TG+V+ ADGG + Sbjct: 254 AGLAGGQFGFATGSVIQADGGLSIGR 279 >4JQC-A nrPDB Length = 282 Score = 178 bits (451), Expect = 3e-45, Method: Composition-based stats. Identities = 54/267 (20%), Positives = 109/267 (40%), Gaps = 15/267 (5%) Query: 14 LPAYRHLFCPDLLRDKVAFITGGGS--GIGFRIAEIFMRHGCHTVIASRSLPRVLTAARK 71 +P H+ L K +TG S I + IA+ R G ++ ++ + Sbjct: 15 VPRGSHM---GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQN-DKLKGRVEE 70 Query: 72 LAGATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAG-----ALS 126 A G + L DV ++ + K + + D ++ A++ Sbjct: 71 FAAQLGSDIV-LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVT 129 Query: 127 FNAFKTVMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVD 186 FK DI + +++ + G ++ ++ R G AKA+++ Sbjct: 130 REGFKIAHDISSYSFVAMAKACRSML--NPGSALLTLSYLGAERAIPNYNVMGLAKASLE 187 Query: 187 AMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIA 246 A R++A GP+ +RVN+++ GPI T + + L+ +P++R ++ Sbjct: 188 ANVRYMANAMGPEGVRVNAISAGPIR-TLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVG 246 Query: 247 HSVLYLASPLASYVTGAVLVADGGAWL 273 +S +L S L++ ++G V+ DGG + Sbjct: 247 NSAAFLCSDLSAGISGEVVHVDGGFSI 273 >4CR6-A nrPDB Length = 271 Score = 177 bits (450), Expect = 4e-45, Method: Composition-based stats. Identities = 66/257 (25%), Positives = 106/257 (41%), Gaps = 14/257 (5%) Query: 23 PDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLP 82 P L K A +TG GIG E ++R G V PR+ + G +P Sbjct: 10 PGRLAGKAAIVTGAAGGIGRATVEAYLREGASVVAMDL-APRLAATRYEEPG-----AIP 63 Query: 83 LSMDVRAPPAVMAAVDQALKEFGRIDILINCAAG-NFLCPAGALSFNAFKTVMDIDTSGT 141 ++ D+ A+ AA+ A+ G +DIL+ A LS + +D++ +GT Sbjct: 64 IACDLADRAAIDAAMADAVARLGGLDILVAGGALKGGTGNFLDLSDADWDRYVDVNMTGT 123 Query: 142 FNVSRVLYEKFFRDHGG------VIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVE 195 F R G I+ I + + +AK V +TR +AV+ Sbjct: 124 FLTCRAGARAMVAAGAGKDGRSARIITIGSVNSFMAEPEAAAYVAAKGGVAMLTRAMAVD 183 Query: 196 WGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASP 255 I VN +APGP+ T P+ + + L R G E+A + ++LA Sbjct: 184 LARHGILVNMIAPGPVDVTGNNTGYSEPRLA-EQVLDEVALGRPGLPEEVATAAVFLAED 242 Query: 256 LASYVTGAVLVADGGAW 272 +S++TG+ + DGG Sbjct: 243 GSSFITGSTITIDGGLS 259 >2NWQ-A nrPDB Length = 272 Score = 177 bits (449), Expect = 5e-45, Method: Composition-based stats. Identities = 70/247 (28%), Positives = 105/247 (42%), Gaps = 16/247 (6%) Query: 14 LPAYRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLA 73 +P H+ FITG SG G A F G V+ R R+ A +L+ Sbjct: 14 VPRGSHMSS-------TLFITGATSGFGEACARRFAEAGWSLVLTGRREERLQALAGELS 66 Query: 74 GATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLC-PAGALSFNAFKT 132 T R LPL++DVR A+ AAVD +EF + LIN A PA + + + T Sbjct: 67 AKT--RVLPLTLDVRDRAAMSAAVDNLPEEFATLRGLINNAGLALGTDPAQSCDLDDWDT 124 Query: 133 VMDIDTSGTFNVSRVLYEKFFRDHGG-VIVNITATLGNRGQALQVHAGSAKAAVDAMTRH 191 ++D + G +R+L + G IVN+ + G G KA V+ + + Sbjct: 125 MVDTNIKGLLYSTRLLLPRLIAHGAGASIVNLGSVAGKWPYPGSHVYGGTKAFVEQFSLN 184 Query: 192 LAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLS-TKVTASPLQRLGNKTEIAHSVL 250 L + +RV +L PG L R GG QA T A P+ +IA ++ Sbjct: 185 LRCDLQGTGVRVTNLEPGLCESEFSLVRFGGDQARYDKTYAGAHPI----QPEDIAETIF 240 Query: 251 YLASPLA 257 ++ + A Sbjct: 241 WIMNQPA 247 >3ZV3-A nrPDB Length = 281 Score = 177 bits (449), Expect = 6e-45, Method: Composition-based stats. Identities = 65/259 (25%), Positives = 105/259 (40%), Gaps = 19/259 (7%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L +VA ITGG SG+G + + F+ G + +S R+ R+L A G + + Sbjct: 3 LTGEVALITGGASGLGRALVDRFVAEGARVAVLDKSAERL----RELEVAHGGNAVGVVG 58 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNA-----FKTVMDIDTSG 140 DVR+ A ++ L FG+ID LI A A A F + ++ G Sbjct: 59 DVRSLQDQKRAAERCLAAFGKIDTLIPNAGIWDYSTALADLPEDKIDAAFDDIFHVNVKG 118 Query: 141 TFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQN 200 + + G +V + G + K AV + R +A E P Sbjct: 119 YIHAVKACLPALVSSR-GSVVFTISNAGFYPNGGGPLYTATKHAVVGLVRQMAFELAPH- 176 Query: 201 IRVNSLAPGPISGTE-GLRRLGGPQASL------STKVTASPLQRLGNKTEIAHSVLYLA 253 +RVN +APG ++ G LG + S+ + P+ R+ E + ++ A Sbjct: 177 VRVNGVAPGGMNTDLRGPSSLGLSEQSISSVPLADMLKSVLPIGRMPALEEYTGAYVFFA 236 Query: 254 SP-LASYVTGAVLVADGGA 271 + + TGA+L DGG Sbjct: 237 TRGDSLPATGALLNYDGGM 255 >5KOI-A nrPDB Length = 293 Score = 177 bits (448), Expect = 7e-45, Method: Composition-based stats. Identities = 67/255 (26%), Positives = 109/255 (42%), Gaps = 12/255 (4%) Query: 24 DLLRDKVAFITGGGS--GIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCL 81 L++ K I G + + + IA+ G + + LA G + Sbjct: 24 GLMQGKRGLIMGVANNHSLAWGIAKQLAAQGAELAFTYQGDALGKR-VKPLAEQVGSDFV 82 Query: 82 PLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCP-----AGALSFNAFKTVMDI 136 L DV V A ++ K++G +D L++ + A + F M I Sbjct: 83 -LPCDVEDIATVDAVFEEIEKKWGGLDFLVHAIGFSDKTELKGRYADVTTRENFSRTMVI 141 Query: 137 DTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEW 196 V++ + GG I+ +T R G AKAA++AM R+LA ++ Sbjct: 142 SAYSFTEVAQRAEKLM--KDGGSILTLTYGGSTRTIPNYNVMGVAKAALEAMVRYLAADY 199 Query: 197 GPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPL 256 GPQ IRVN+++ GP+ G +G +A S + SPL+R + ++ S +YL S L Sbjct: 200 GPQGIRVNAISAGPVRTLAGA-GIGDARAIFSYQRRNSPLRRTVDIDDVGKSAVYLLSDL 258 Query: 257 ASYVTGAVLVADGGA 271 +S VTG + D G Sbjct: 259 SSGVTGEIHFVDSGY 273 >2QHX-A nrPDB Length = 328 Score = 176 bits (447), Expect = 9e-45, Method: Composition-based stats. Identities = 63/301 (20%), Positives = 103/301 (34%), Gaps = 47/301 (15%) Query: 14 LPAYRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIAS-RSLPRVLTAARKL 72 +P H+ P + VA +TG +G IAE G + RS + L Sbjct: 35 VPRGSHMTAPTV---PVALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSATL 91 Query: 73 AGATGRRCLPLSMDVRAPPA-----------------VMAAVDQALKEFGRIDILINCAA 115 + + D+ V +GR D+L+N A+ Sbjct: 92 NARRPNSAITVQADLSNVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNAS 151 Query: 116 GNFLCPA------GALSFNAFKTVMDI--------DTSGTFNVSRVLY------EKFFRD 155 + P G + M+ + + + + R Sbjct: 152 SFYPTPLLRNDEDGHEPCVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRG 211 Query: 156 HGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTE 215 I+N+ + N+ AK A++ +TR A+E P IRVN + PG + Sbjct: 212 TNYSIINMVDAMTNQPLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGLSVLVD 271 Query: 216 GLRRLGGPQASLSTKVTASPL-QRLGNKTEIAHSVLYLASPLASYVTGAVLVADGGAWLT 274 + P A + PL QR + E++ V++L S A Y+TG + DGG LT Sbjct: 272 DM-----PPAVWEGHRSKVPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSLT 326 Query: 275 F 275 Sbjct: 327 R 327 >2O23-A nrPDB Length = 265 Score = 176 bits (447), Expect = 1e-44, Method: Composition-based stats. Identities = 72/263 (27%), Positives = 114/263 (43%), Gaps = 24/263 (9%) Query: 25 LLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLS 84 ++ VA ITGG SG+G AE + G V+ A+KL G C+ Sbjct: 9 SVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKL----GNNCVFAP 64 Query: 85 MDVRAPPAVMAAVDQALKEFGRIDILINCAAGNF------LCPAGALSFNAFKTVMDIDT 138 DV + V A+ A +FGR+D+ +NCA L + F+ V+D++ Sbjct: 65 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 124 Query: 139 SGTFNVSRVLYEKFFRD------HGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHL 192 GTFNV R++ + ++ GVI+N + GQ Q ++K + MT + Sbjct: 125 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 184 Query: 193 AVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQ-RLGNKTEIAHSV-L 250 A + P IRV ++APG P+ + + P RLG+ E AH V Sbjct: 185 ARDLAPIGIRVMTIAPGLFGTPLLTS---LPEKVCNFLASQVPFPSRLGDPAEYAHLVQA 241 Query: 251 YLASPLASYVTGAVLVADGGAWL 273 + +P ++ G V+ DG + Sbjct: 242 IIENP---FLNGEVIRLDGAIRM 261 >5CFZ-A nrPDB Length = 305 Score = 175 bits (443), Expect = 3e-44, Method: Composition-based stats. Identities = 56/273 (20%), Positives = 111/273 (40%), Gaps = 22/273 (8%) Query: 18 RHLFCPDL----------LRDKVAFITGGGS--GIGFRIAEIFMRHGCHTVIASRSLPRV 65 +H+ PDL L K +TG S I + IA+ R G ++ ++ Sbjct: 29 QHMDSPDLGTDDDDKMGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQN-DKL 87 Query: 66 LTAARKLAGATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAG-- 123 + A G + L DV ++ + K + + D ++ Sbjct: 88 KGRVEEFAAQLGSDIV-LQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGD 146 Query: 124 ---ALSFNAFKTVMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGS 180 A++ FK DI + +++ + G ++ ++ R G Sbjct: 147 YVNAVTREGFKIAHDISSYSFVAMAKACRSML--NPGSALLTLSYLGAERAIPNYNVMGL 204 Query: 181 AKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLG 240 AKA+++A R++A GP+ +RVN+++ GPI T + + L+ +P++R Sbjct: 205 AKASLEANVRYMANAMGPEGVRVNAISAGPIR-TLAASGIKDFRKMLAHCEAVTPIRRTV 263 Query: 241 NKTEIAHSVLYLASPLASYVTGAVLVADGGAWL 273 ++ +S +L S L++ ++G V+ DGG + Sbjct: 264 TIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSI 296 >1E3W-A nrPDB Length = 261 Score = 174 bits (441), Expect = 4e-44, Method: Composition-based stats. Identities = 71/263 (26%), Positives = 116/263 (44%), Gaps = 24/263 (9%) Query: 25 LLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLS 84 ++ VA ITGG SG+G A+ + G V+ T A+KL G C+ Sbjct: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKL----GGNCIFAP 62 Query: 85 MDVRAPPAVMAAVDQALKEFGRIDILINCAAGN------FLCPAGALSFNAFKTVMDIDT 138 +V + V AA+ A ++FGRID+ +NCA + F+ V++++ Sbjct: 63 ANVTSEKEVQAALTLAKEKFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNL 122 Query: 139 SGTFNVSRVLYEKFFRD------HGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHL 192 GTFNV R++ ++ GVI+N + GQ Q ++K + MT + Sbjct: 123 IGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182 Query: 193 AVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQ-RLGNKTEIAHSV-L 250 A + P IRV ++APG + P + + P RLG+ E AH V + Sbjct: 183 ARDLAPIGIRVVTIAPGLFATPLLT---TLPDTVRNFLASQVPFPSRLGDPAEYAHLVQM 239 Query: 251 YLASPLASYVTGAVLVADGGAWL 273 + +P ++ G V+ DG + Sbjct: 240 VIENP---FLNGEVIRLDGAIRM 259 >2GDZ-A nrPDB Length = 267 Score = 173 bits (440), Expect = 5e-44, Method: Composition-based stats. Identities = 42/195 (21%), Positives = 82/195 (42%), Gaps = 14/195 (7%) Query: 25 LLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATG-RRCLPL 83 ++ KVA +TG GIG AE + G + +L + L ++ L + Sbjct: 4 MVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALHEQFEPQKTLFI 63 Query: 84 SMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFN 143 DV + + + FGR+DIL+N A N + ++ + I+ + Sbjct: 64 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVIS 115 Query: 144 VSRVLYEKFFRDH---GGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRH--LAVEWGP 198 + + + + + GG+I+N+++ G A Q ++K + TR LA Sbjct: 116 GTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMN 175 Query: 199 QNIRVNSLAPGPISG 213 +R+N++ PG ++ Sbjct: 176 SGVRLNAICPGFVNT 190 >4NR0-A nrPDB Length = 273 Score = 173 bits (440), Expect = 6e-44, Method: Composition-based stats. Identities = 56/255 (21%), Positives = 96/255 (37%), Gaps = 9/255 (3%) Query: 24 DLLRDKVAFITGGGS--GIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCL 81 L K A I G S I IA R G ++ +G R L Sbjct: 2 GFLTGKRALIVGVASKLSIASGIAAAMHREGAELAFTYQNDKLRGRVEEFASGWGSRPEL 61 Query: 82 PLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAG-----ALSFNAFKTVMDI 136 DV + A K + +DI+++ + F+ DI Sbjct: 62 CFPCDVADDSQIEAVFAALGKHWDGLDIIVHSVGFAPGDQLDGDFTAVTTREGFRIAHDI 121 Query: 137 DTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEW 196 +++ + + G ++ ++ R G AKA+++A R+LA Sbjct: 122 SAYSFIALAK-AGREMMKGRNGSLLTLSYLGAERTMPNYNVMGMAKASLEAGVRYLAGSL 180 Query: 197 GPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPL 256 G + RVN+++ GPI T + + L+ +PL+R E+ ++ +L S L Sbjct: 181 GAEGTRVNAVSAGPIR-TLAASGIKSFRKMLAANERQTPLRRNVTIEEVGNAGAFLCSDL 239 Query: 257 ASYVTGAVLVADGGA 271 AS ++G +L DGG Sbjct: 240 ASGISGEILYVDGGF 254 >1BDB-A nrPDB Length = 277 Score = 173 bits (440), Expect = 6e-44, Method: Composition-based stats. Identities = 59/259 (22%), Positives = 98/259 (37%), Gaps = 19/259 (7%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L+ + ITGG SG+G + + F+ G + +S R+ +L G L + Sbjct: 3 LKGEAVLITGGASGLGRALVDRFVAEGAKVAVLDKSAERLA----ELETDHGDNVLGIVG 58 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAG-NFLCPAGALSFN----AFKTVMDIDTSG 140 DVR+ A + + FG+ID LI A ++ L AF V I+ G Sbjct: 59 DVRSLEDQKQAASRCVARFGKIDTLIPNAGIWDYSTALVDLPEESLDAAFDEVFHINVKG 118 Query: 141 TFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQN 200 + + G ++ + G +AK A+ + R LA E P Sbjct: 119 YIHAVKACLPALVASR-GNVIFTISNAGFYPNGGGPLYTAAKHAIVGLVRELAFELAPY- 176 Query: 201 IRVNSLAPGPISGTE-------GLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLA 253 +RVN + G I+ + + P+ R+ E + ++ A Sbjct: 177 VRVNGVGSGGINSDLRGPSSLGMGSKAISTVPLADMLKSVLPIGRMPEVEEYTGAYVFFA 236 Query: 254 SP-LASYVTGAVLVADGGA 271 + A+ TGA+L DGG Sbjct: 237 TRGDAAPATGALLNYDGGL 255 >4GKB-A nrPDB Length = 258 Score = 173 bits (438), Expect = 9e-44, Method: Composition-based stats. Identities = 70/251 (27%), Positives = 105/251 (41%), Gaps = 8/251 (3%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L+DKV +TGG SGIG I+ V+ +R P A R L + Sbjct: 5 LQDKVVIVTGGASGIGGAISMRLAEERAIPVVFARHAPDG--AFLDALAQRQPRATYLPV 62 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 +++ AV Q + FGR+D L+N A N A +AF ++ + + ++ Sbjct: 63 ELQDDAQCRDAVAQTIATFGRLDGLVNNAGVNDGIGLDA-GRDAFVASLERNLIHYYAMA 121 Query: 146 RVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNS 205 G IVNI++ GQ ++K A A+TR AV +RVN+ Sbjct: 122 HYCVPHLKATR-GAIVNISSKTAVTGQGNTSGYCASKGAQLALTREWAVALREHGVRVNA 180 Query: 206 LAPGPISGT---EGLRRLGGPQASLSTKVTASPLQ-RLGNKTEIAHSVLYLASPLASYVT 261 + P + + P+A L+ PL R EIA + ++L SP AS+ T Sbjct: 181 VIPAEVMTPLYRNWIATFEDPEAKLAEIAAKVPLGRRFTTPDEIADTAVFLLSPRASHTT 240 Query: 262 GAVLVADGGAW 272 G L DGG Sbjct: 241 GEWLFVDGGYT 251 >3K2E-A nrPDB Length = 296 Score = 172 bits (436), Expect = 2e-43, Method: Composition-based stats. Identities = 61/274 (22%), Positives = 102/274 (37%), Gaps = 12/274 (4%) Query: 19 HLFCPDLLRDKVAFITGGG--SGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGAT 76 + L+ K I G + + IA+ G + S LA + Sbjct: 21 SMRTGMLMEGKKGVIIGVANDKSLAWGIAKAVCAQGAEVALTYLS-ETFKKRVDPLAESL 79 Query: 77 GRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAA----GNFLCPAGALSFNAFKT 132 G + L + DV +V +E+G +D +++ A S F T Sbjct: 80 GVK-LTVPCDVSDAESVDNMFKVLAEEWGSLDFVVHAVAFSDKNELKGRYVDTSLGNFLT 138 Query: 133 VMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHL 192 M I ++ +GG I+ ++ + G KAA++A ++L Sbjct: 139 SMHISCYSFTYIASKAEPLM--TNGGSILTLSYYGAEKVVPHYNVMGVCKAALEASVKYL 196 Query: 193 AVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYL 252 AV+ G Q IRVN+++ GP+ T + L+ SPL+R ++ + LYL Sbjct: 197 AVDLGKQQIRVNAISAGPVR-TLASSGISDFHYILTWNKYNSPLRRNTTLDDVGGAALYL 255 Query: 253 ASPLASYVTGAVLVADGGAWLTFPNGVKGLPDFA 286 S L TG + D G + V PD + Sbjct: 256 LSDLGRGTTGETVHVDCGYHVVGMKSVDA-PDIS 288 >1P33-A nrPDB Length = 289 Score = 172 bits (436), Expect = 2e-43, Method: Composition-based stats. Identities = 63/285 (22%), Positives = 103/285 (36%), Gaps = 44/285 (15%) Query: 30 VAFITGGGSGIGFRIAEIFMRHGCHTVIAS-RSLPRVLTAARKLAGATGRRCLPLSMDVR 88 VA +TG +G IAE G + RS T A L + + D+ Sbjct: 9 VALVTGAAKRLGSSIAEALHAEGYTVCLHYHRSAADASTLAATLNARRPNSAITVQADLS 68 Query: 89 APPA-----------------VMAAVDQALKEFGRIDILINCAAGNFLCPA------GAL 125 A VD +GR D+L+N A+ + P Sbjct: 69 NVATASFSETDGSVPVTLFSRCSALVDACYMHWGRCDVLVNNASSFYPTPLLRKDAGEGG 128 Query: 126 SFNAFKTVMDI--------DTSGTFNVSRVLYEKFF------RDHGGVIVNITATLGNRG 171 S K +++ + + + + ++ R IVN+ + ++ Sbjct: 129 SSVGDKESLEVAAADLFGSNAIAPYFLIKAFAQRVADTRAEQRGTSYSIVNMVDAMTSQP 188 Query: 172 QALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKV 231 AK A++ +TR A+E IRVN ++PG + + P + Sbjct: 189 LLGYTMYTMAKEALEGLTRSAALELASLQIRVNGVSPGLSVLPDDM-----PFSVQEDYR 243 Query: 232 TASPL-QRLGNKTEIAHSVLYLASPLASYVTGAVLVADGGAWLTF 275 PL QR + E++ V++L SP A Y+TG + DGG LT Sbjct: 244 RKVPLYQRNSSAEEVSDVVIFLCSPKAKYITGTCIKVDGGYSLTR 288 >4M89-A nrPDB Length = 261 Score = 172 bits (435), Expect = 2e-43, Method: Composition-based stats. Identities = 56/257 (21%), Positives = 94/257 (36%), Gaps = 11/257 (4%) Query: 24 DLLRDKVAFITG--GGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCL 81 L+ K ITG I + IA+ G + ++ RK+A L Sbjct: 2 GFLQGKKILITGMISERSIAYGIAKACREQGAELAFTYV-VDKLEERVRKMAAELDSE-L 59 Query: 82 PLSMDVRAPPAVMAAVDQALKEFGRIDILINCAA-----GNFLCPAGALSFNAFKTVMDI 136 DV + + K + +D L++ ++S AF T +I Sbjct: 60 VFRCDVASDDEINQVFADLGKHWDGLDGLVHSIGFAPKEALSGDFLDSISREAFNTAHEI 119 Query: 137 DTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEW 196 +++ R IV ++ R G AKA+++A R A Sbjct: 120 SAYSLPALAKAA-RPMMRGRNSAIVALSYLGAVRAIPNYNVMGMAKASLEAGIRFTAACL 178 Query: 197 GPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPL 256 G + IR N ++ GPI T + L +PL+R E+ ++ +L S L Sbjct: 179 GKEGIRCNGISAGPIK-TLAASGIADFGKLLGHVAAHNPLRRNVTIEEVGNTAAFLLSDL 237 Query: 257 ASYVTGAVLVADGGAWL 273 +S +TG + DGG + Sbjct: 238 SSGITGEITYVDGGYSI 254 >4J3F-A nrPDB Length = 280 Score = 171 bits (434), Expect = 3e-43, Method: Composition-based stats. Identities = 54/266 (20%), Positives = 99/266 (37%), Gaps = 15/266 (5%) Query: 14 LPAYRHLFCPDLLRDKVAFITG--GGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARK 71 +P H+ L K ITG I + IA+ R G K Sbjct: 15 VPRGSHM---GFLAGKKILITGLLSNKSIAYGIAKAMHREGAELAFTYVGQ--FKDRVEK 69 Query: 72 LAGATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGA-----LS 126 L + L DV + + + K + +D +++ A ++ Sbjct: 70 LCAEFNPAAV-LPCDVISDQEIKDLFVELGKVWDGLDAIVHSIAFAPRDQLEGNFIDCVT 128 Query: 127 FNAFKTVMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVD 186 F DI +++ ++ +V +T + G AKA+++ Sbjct: 129 REGFSIAHDISAYSFAALAKE-GRSMMKNRNASMVALTYIGAEKAMPSYNTMGVAKASLE 187 Query: 187 AMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIA 246 A R+ A+ G I+VN+++ GPI T + + L SPL++ + E+ Sbjct: 188 ATVRYTALALGEDGIKVNAVSAGPIK-TLAASGISNFKKMLDYNAMVSPLKKNVDIMEVG 246 Query: 247 HSVLYLASPLASYVTGAVLVADGGAW 272 ++V +L S +A+ +TG V+ D G Sbjct: 247 NTVAFLCSDMATGITGEVVHVDAGYH 272 >3PXX-A nrPDB Length = 287 Score = 171 bits (433), Expect = 3e-43, Method: Composition-based stats. Identities = 70/286 (24%), Positives = 106/286 (37%), Gaps = 38/286 (13%) Query: 24 DLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASR-----------SLPRVLTAARKL 72 ++DKV +TGG G G A G ++ + R L A Sbjct: 6 GRVQDKVVLVTGGARGQGRSHAVKLAEEGADIILFDICHDIETNEYPLATSRDLEEAGLE 65 Query: 73 AGATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKT 132 TGR+ +DVR AV + A+ EFG++D+++ A L L AF Sbjct: 66 VEKTGRKAYTAEVDVRDRAAVSRELANAVAEFGKLDVVVANAGICPLG--AHLPVQAFAD 123 Query: 133 VMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVH-----------AGSA 181 D+D G N G I+ + G A A Sbjct: 124 AFDVDFVGVINTVHAALPYL--TSGASIITTGSVAGLIAAAQPPGAGGPQGPGGAGYSYA 181 Query: 182 KAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEG----LRRLGGPQASLSTKVTAS--- 234 K VD+ T LA + PQ+IR N + P ++ + R P ++ A Sbjct: 182 KQLVDSYTLQLAAQLAPQSIRANVIHPTNVNTDMLNSAPMYRQFRPDLEAPSRADALLAF 241 Query: 235 -PLQRLGNK----TEIAHSVLYLASPLASYVTGAVLVADGGAWLTF 275 +Q + ++I+++V +LAS + YVTG D GA L F Sbjct: 242 PAMQAMPTPYVEASDISNAVCFLASDESRYVTGLQFKVDAGAMLKF 287 >2BFA-A nrPDB Length = 288 Score = 168 bits (427), Expect = 2e-42, Method: Composition-based stats. Identities = 60/285 (21%), Positives = 97/285 (34%), Gaps = 44/285 (15%) Query: 30 VAFITGGGSGIGFRIAEIFMRHGCHTVIAS-RSLPRVLTAARKLAGATGRRCLPLSMDVR 88 VA +TG +G IAE G + RS + L + + D+ Sbjct: 8 VALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQADLS 67 Query: 89 APPA-----------------VMAAVDQALKEFGRIDILINCAAGNFLCPA------GAL 125 V +GR D+L+N A+ + P G Sbjct: 68 NVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDGHE 127 Query: 126 SFNAFKTVMDI--------DTSGTFNVSRVLY------EKFFRDHGGVIVNITATLGNRG 171 + M+ + + + + R I+N+ + N+ Sbjct: 128 PCVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINMVDAMTNQP 187 Query: 172 QALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKV 231 AK A++ +TR A+E P IRVN + PG + + P A Sbjct: 188 LLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGLSVLVDDM-----PPAVWEGHR 242 Query: 232 TASPL-QRLGNKTEIAHSVLYLASPLASYVTGAVLVADGGAWLTF 275 + PL QR + E++ V++L S A Y+TG + DGG LT Sbjct: 243 SKVPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSLTR 287 >3OML-A nrPDB Length = 613 Score = 163 bits (414), Expect = 7e-41, Method: Composition-based stats. Identities = 50/246 (20%), Positives = 87/246 (35%), Gaps = 28/246 (11%) Query: 27 RDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASR--------SLPRVLTAARKLAGATGR 78 +VA +TG G+G+G A +F G V+ + R G Sbjct: 18 DGRVAVVTGAGAGLGREYALLFAERGAKVVVNDLGGTHSGDGASQRAADIVVDEIRKAGG 77 Query: 79 RCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDT 138 + D + ++ A+K FGR+DIL+N A S + V D+ Sbjct: 78 EAV---ADYNSVIDGAKVIETAIKAFGRVDILVNNAGILRDRSLVKTSEQDWNLVNDVHL 134 Query: 139 SGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGP 198 G+F ++ + + + G I+ ++ G G QV+ +AK + + +A+E Sbjct: 135 KGSFKCTQAAFPYMKKQNYGRIIMTSSNSGIYGNFGQVNYTAAKMGLIGLANTVAIEGAR 194 Query: 199 QNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLAS---- 254 N+ N + P + + P + IA V YL Sbjct: 195 NNVLCNVIVPTA--ASRMTEGIL-PDILFNELK----------PKLIAPVVAYLCHESCE 241 Query: 255 PLASYV 260 SY+ Sbjct: 242 DNGSYI 247 >5I9N-A nrPDB Length = 276 Score = 160 bits (406), Expect = 5e-40, Method: Composition-based stats. Identities = 57/255 (22%), Positives = 92/255 (36%), Gaps = 12/255 (4%) Query: 24 DLLRDKVAFITG--GGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCL 81 L K +TG I + IA+ R G R + A G L Sbjct: 2 GFLDGKRILLTGLLSNRSIAYGIAKACKREGAELAFTYVG-DRFKDRITEFAAEFGSE-L 59 Query: 82 PLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNF-----LCPAGALSFNAFKTVMDI 136 DV + A + +D L++ L+ F+ DI Sbjct: 60 VFPCDVADDAQIDALFASLKTHWDSLDGLVHSIGFAPREAIAGDFLDGLTRENFRIAHDI 119 Query: 137 DTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEW 196 +++ D ++ ++ R G AKAA++A R+LAV Sbjct: 120 SAYSFPALAKAALPMLSDD--ASLLTLSYLGAERAIPNYNTMGLAKAALEASVRYLAVSL 177 Query: 197 GPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPL 256 G + +RVN+++ GPI T + L + SPL+R ++ ++ +L S L Sbjct: 178 GAKGVRVNAISAGPIK-TLAASGIKSFGKILDFVESNSPLKRNVTIEQVGNAGAFLLSDL 236 Query: 257 ASYVTGAVLVADGGA 271 AS VT V+ D G Sbjct: 237 ASGVTAEVMHVDSGF 251 >1A27-A nrPDB Length = 289 Score = 160 bits (406), Expect = 5e-40, Method: Composition-based stats. Identities = 56/243 (23%), Positives = 94/243 (38%), Gaps = 25/243 (10%) Query: 30 VAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLP-----LS 84 V ITG SGIG +A + +L + T R A C P L Sbjct: 4 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 63 Query: 85 MDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNV 144 +DVR +V AA ++ + GR+D+L+ A L P AL +A +V+D++ GT + Sbjct: 64 LDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 121 Query: 145 SRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVN 204 + R G ++ + G G ++K A++ + LAV P + ++ Sbjct: 122 LQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLS 181 Query: 205 SLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGN---------------KTEIAHSV 249 + GP+ + LG P+ L + R E+A Sbjct: 182 LIECGPVHTAFMEKVLGSPEEVLDRTDIHT-FHRFYQYLAHSKQVFREAAQNPEEVAE-- 238 Query: 250 LYL 252 ++L Sbjct: 239 VFL 241 >6CGE-A nrPDB Length = 328 Score = 158 bits (400), Expect = 2e-39, Method: Composition-based stats. Identities = 56/243 (23%), Positives = 94/243 (38%), Gaps = 25/243 (10%) Query: 30 VAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLP-----LS 84 V ITG SGIG +A + +L + T R A C P L Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64 Query: 85 MDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNV 144 +DVR +V AA ++ + GR+D+L+ A L P AL +A +V+D++ GT + Sbjct: 65 LDVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122 Query: 145 SRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVN 204 + R G ++ + G G ++K A++ + LAV P + ++ Sbjct: 123 LQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLS 182 Query: 205 SLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGN---------------KTEIAHSV 249 + GP+ + LG P+ L + R E+A Sbjct: 183 LIECGPVHTAFMEKVLGSPEEVLDRTDIHT-FHRFYQYLAHSKQVFREAAQNPEEVAE-- 239 Query: 250 LYL 252 ++L Sbjct: 240 VFL 242 >4NK4-A nrPDB Length = 301 Score = 158 bits (400), Expect = 3e-39, Method: Composition-based stats. Identities = 54/254 (21%), Positives = 105/254 (41%), Gaps = 11/254 (4%) Query: 24 DLLRDKVAFITGGGS--GIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCL 81 ++L+ K I G + I + IA++ G + + K T Sbjct: 37 NILKGKRGLIMGVANDHSIAWGIAKVLHSAGAQLAFSYQGESIGKRL--KPLALTVDSDF 94 Query: 82 PLSMDVRAPPAVMAAVDQALKEFGRIDILINCAA----GNFLCPAGALSFNAFKTVMDID 137 + +V P ++ ++ + + +D +++ A P S + F M + Sbjct: 95 MIPCNVEDPSSMDLLFERIKERWETLDFVVHSIAFSDKNELRGPYYNTSRDNFIQTMLVS 154 Query: 138 TSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWG 197 + R + HGG ++ +T R AK+A+++ T++LA ++G Sbjct: 155 CFSFTEIVRRAAQLM--PHGGAMITLTYGGSMRVVPNYNAMAPAKSALESSTKYLACDYG 212 Query: 198 PQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLA 257 NIR+N+++ GP+ G + + + SPL+R + +I +S LYL S L+ Sbjct: 213 GMNIRINAISAGPVRTLAGA-SISNGRDIAAWSKENSPLKRTVSLEDIGNSALYLLSYLS 271 Query: 258 SYVTGAVLVADGGA 271 + VTG + D G Sbjct: 272 NGVTGEIHYVDCGY 285 >3PPI-A nrPDB Length = 281 Score = 152 bits (385), Expect = 1e-37, Method: Composition-based stats. Identities = 63/269 (23%), Positives = 103/269 (38%), Gaps = 23/269 (8%) Query: 19 HLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGR 78 + A ++GG G+G G VIA + + A +L G Sbjct: 21 SMVTIKQFEGASAIVSGGAGGLGEATVRRLHADGLGVVIADLAAEKGKALADEL----GN 76 Query: 79 RCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGA------LSFNAFKT 132 R +S +V + +V+AA++ A + GR+ + G + F Sbjct: 77 RAEFVSTNVTSEDSVLAAIEAA-NQLGRLRYAVVAHGGFGVAQRIVQRDGSPADMGGFTK 135 Query: 133 VMDIDTSGTFNVSR------VLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVD 186 +D+ +GT+NV+R E G +V + G GQ Q +AKA V Sbjct: 136 TIDLYLNGTYNVARLVAASIAAAEPRENGERGALVLTASIAGYEGQIGQTAYAAAKAGVI 195 Query: 187 AMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPL-QRLGNKTEI 245 +T A + IRVN++APG + + +L+ P +RLG E Sbjct: 196 GLTIAAARDLSSAGIRVNTIAPGTMKTPIMESV---GEEALAKFAANIPFPKRLGTPDEF 252 Query: 246 AHSVLYLASPLASYVTGAVLVADGGAWLT 274 A + +L + Y+ G V+ DG T Sbjct: 253 ADAAAFLLTN--GYINGEVMRLDGAQRFT 279 >4DRY-A nrPDB Length = 281 Score = 151 bits (381), Expect = 4e-37, Method: Composition-based stats. Identities = 59/251 (23%), Positives = 105/251 (41%), Gaps = 22/251 (8%) Query: 18 RHLFCPDLL-------RDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAAR 70 +L+ ++ ++A +TGGG+G+G IA+ G VI R + AA Sbjct: 16 ENLYFQSMMAQGKGSGEGRIALVTGGGTGVGRGIAQALSAEGYSVVITGRRPDVLDAAAG 75 Query: 71 KLAGATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGN-FLCPAGALSFNA 129 ++ G TG + DV P V A EF R+D+L+N A N P ++F Sbjct: 76 EIGGRTGNIVRAVVCDVGDPDQVAALFAAVRAEFARLDLLVNNAGSNVPPVPLEEVTFEQ 135 Query: 130 FKTVMDIDTSGTFNVSRVLYEKFFRD--HGGVIVNITATLGNRGQALQVHAGSAKAAVDA 187 + ++ + +G F ++ + GG I+N + + + K A+ Sbjct: 136 WNGIVAANLTGAFLCTQHAFRMMKAQTPRGGRIINNGSISAQTPRPNSAPYTATKHAITG 195 Query: 188 MTRHLAVEWGPQNIRVNSLAPGPIS----GTEGLRRLGGPQASLSTKVTASPLQRLGNKT 243 +T+ A++ R++ +A G I T+ R+ + +V A P Sbjct: 196 LTKSTALDG-----RMHDIACGQIDIGNAATDMTARMSTGVLQANGEVAAEP---TIPIE 247 Query: 244 EIAHSVLYLAS 254 IA +V+Y+AS Sbjct: 248 HIAEAVVYMAS 258 >5ILO-A nrPDB Length = 271 Score = 151 bits (381), Expect = 4e-37, Method: Composition-based stats. Identities = 56/253 (22%), Positives = 98/253 (38%), Gaps = 20/253 (7%) Query: 25 LLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLS 84 R K A +TGG GIG ++++ + G V + + A + + + Sbjct: 12 SFRGKNAVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAAHPTQSVMIIK 71 Query: 85 MDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNV 144 MDV V A ++ K FG IDI++N A + + + ++ G N Sbjct: 72 MDVANKKGVEATYEEIAKTFGNIDIVVNVAGI--------FNDKDVQRTLLVNLGGIINS 123 Query: 145 SRVLYEKFFRD---HGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVE--WGPQ 199 + +D GG++VN+++ +G + G+ KA + TR LA E + Sbjct: 124 TLSALPYMGKDNGGKGGIVVNMSSVVGLDPMFIIPVYGATKAGIINFTRCLANEKYYQRS 183 Query: 200 NIRVNSLAPGPISG---TEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPL 256 I+ ++ PG T ++ P+ S T L + A + + L Sbjct: 184 GIKFVTVCPGATMTDMFTNFTEKIIFPETSDETYRILDRLNK----QSAADVSRCILNVL 239 Query: 257 ASYVTGAVLVADG 269 GAV V +G Sbjct: 240 EKDKNGAVYVIEG 252 >2PD3-A nrPDB Length = 275 Score = 149 bits (376), Expect = 1e-36, Method: Composition-based stats. Identities = 59/263 (22%), Positives = 106/263 (40%), Gaps = 11/263 (4%) Query: 24 DLLRDKVAFITG--GGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCL 81 L+ K I G I + IA+ G + + R +A Sbjct: 2 GFLKGKKGLIVGVANNKSIAYGIAQSCFNQGATLAFTYLN-ESLEKRVRPIAQELNSP-Y 59 Query: 82 PLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAG----ALSFNAFKTVMDID 137 +DV + + K+ G +D +++ A S +AF T M+I Sbjct: 60 VYELDVSKEEHFKSLYNSVKKDLGSLDFIVHSVAFAPKEALEGSLLETSKSAFNTAMEIS 119 Query: 138 TSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWG 197 ++ L ++G ++ ++ + A G AKAA+++ R+LAV+ G Sbjct: 120 VYSLIELTNTLKPLL--NNGASVLTLSYLGSTKYMAHYNVMGLAKAALESAVRYLAVDLG 177 Query: 198 PQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLA 257 +IRVN+L+ GPI T + + L +PL++ + E+ ++ +YL S L+ Sbjct: 178 KHHIRVNALSAGPIR-TLASSGIADFRMILKWNEINAPLRKNVSLEEVGNAGMYLLSSLS 236 Query: 258 SYVTGAVLVADGGAWLTFPNGVK 280 S V+G V D G + V+ Sbjct: 237 SGVSGEVHFVDAGYHVMGMGAVE 259 >4Q9N-A nrPDB Length = 298 Score = 145 bits (367), Expect = 2e-35, Method: Composition-based stats. Identities = 69/281 (24%), Positives = 118/281 (41%), Gaps = 36/281 (12%) Query: 26 LRDKVAFITGGG--SGIGFRIAEIFMRHGCHTVIA---------SRSLP-RVLTAARKLA 73 L K+AFI G G +G G+ IA++ G ++ S+SL A+R+L+ Sbjct: 6 LTGKIAFIAGIGDDNGYGWGIAKMLAEAGATILVGTWVPIYKIFSQSLELGKFNASRELS 65 Query: 74 GA---TGRRCLPLSMDVRAPPA------------------VMAAVDQALKEFGRIDILIN 112 T + P+ P V V+Q K FG IDIL++ Sbjct: 66 NGELLTFAKIYPMDASFDTPEDIPQEILENKRYKDLSGYTVSEVVEQVKKHFGHIDILVH 125 Query: 113 CAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQ 172 A + L + + + TS +S + + + G +++T R Sbjct: 126 SLANSPEIAKPLLDTSRKGYLAALSTSSYSFISLLSHFGPIMNAGASTISLTYLASMRAV 185 Query: 173 ALQVH-AGSAKAAVDAMTRHLAVEWGPQ-NIRVNSLAPGPISGTEGLRRLGGPQASLSTK 230 +AKAA+++ T+ LA E G + +RVN+++ GP++ G + +G + + Sbjct: 186 PGYGGGMNAAKAALESDTKVLAWEAGRRWGVRVNTISAGPLASRAG-KAIGFIERMVDYY 244 Query: 231 VTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVADGGA 271 +PL ++ + +L SPLAS +TG L D GA Sbjct: 245 QDWAPLPSPMEAEQVGAAAAFLVSPLASAITGETLYVDHGA 285 >1ENP-A nrPDB Length = 312 Score = 141 bits (357), Expect = 2e-34, Method: Composition-based stats. Identities = 68/284 (23%), Positives = 114/284 (40%), Gaps = 36/284 (12%) Query: 23 PDLLRDKVAFITGGG--SGIGFRIAEIFMRHGCHTVIA------------------SRSL 62 P LR K AFI G +G G+ +A+ G ++ +S Sbjct: 13 PIDLRGKRAFIAGIADDNGYGWAVAKSLAAAGAEILVGTWVPALNIFETSLRRGKFDQSR 72 Query: 63 PRVLTAARKLAGATGRRCLP-----LSMDV--------RAPPAVMAAVDQALKEFGRIDI 109 + ++ + + DV + V A + ++FG IDI Sbjct: 73 VLPDGSLMEIKKVYPLDAVFDNPEDVPEDVKANKRYAGSSNWTVQEAAECVRQDFGSIDI 132 Query: 110 LINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGN 169 L++ A L + + I S VS + + + GG +++T Sbjct: 133 LVHSLANGPEVSKPLLETSRKGYLAAISASSYSFVSLLSHFLPIMNPGGASISLTYIASE 192 Query: 170 RGQALQ-VHAGSAKAAVDAMTRHLAVEWG-PQNIRVNSLAPGPISGTEGLRRLGGPQASL 227 R SAKAA+++ TR LA E G QNIRVN+++ GP+ G+ + +G + Sbjct: 193 RIIPGYGGGMSSAKAALESDTRVLAFEAGRKQNIRVNTISAGPL-GSRAAKAIGFIDTMI 251 Query: 228 STKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVADGGA 271 +P+Q+ E+ ++ +L SPLAS +TGA + D G Sbjct: 252 EYSYNNAPIQKTLTADEVGNAAAFLVSPLASAITGATIYVDNGL 295 >3E9N-A nrPDB Length = 245 Score = 133 bits (336), Expect = 7e-32, Method: Composition-based stats. Identities = 48/228 (21%), Positives = 86/228 (37%), Gaps = 16/228 (7%) Query: 24 DLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPL 83 L+ K+A +TG G+G I + R H V A P L A ++ G P+ Sbjct: 1 MSLKKKIAVVTGATGGMGIEIVKDLSRD--HIVYALGRNPEHLAALAEIEG-----VEPI 53 Query: 84 SMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFN 143 D+ VD+ K +D L++ AA A S + +D++ Sbjct: 54 ESDIVKEVLEEGGVDKL-KNLDHVDTLVHAAAVARDTTIEAGSVAEWHAHLDLNVIVPAE 112 Query: 144 VSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRV 203 +SR L R G ++ I + GN ++K A+ + E IRV Sbjct: 113 LSRQLLPAL-RAASGCVIYINSGAGNGPHPGNTIYAASKHALRGLADAFRKEEANNGIRV 171 Query: 204 NSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLY 251 ++++PGP + + + ++ EIA+++ + Sbjct: 172 STVSPGPTNTPMLQGLMDSQGTNFRPEI-------YIEPKEIANAIRF 212 >2O2S-A nrPDB Length = 315 Score = 133 bits (335), Expect = 9e-32, Method: Composition-based stats. Identities = 63/291 (21%), Positives = 99/291 (34%), Gaps = 40/291 (13%) Query: 22 CPDLLRDKVAFITGGGS--GIGFRIAEIFMRHGCHTVIASRS----------LPRVLTAA 69 P LR + AF+ G G G+ IA+ G + + L Sbjct: 3 FPIDLRGQTAFVAGVADSHGYGWAIAKHLASAGARVALGTWPPVLGLFQKSLQSGRLDED 62 Query: 70 RKLAGA---TGRRCLPLSMDVRAPPAV------------------MAAVDQALKEFGRID 108 RKL PL P V + ++ G ID Sbjct: 63 RKLPDGSLIEFAGVYPLDAAFDKPEDVPQDIKDNKRYAGVDGYTIKEVAVKVKQDLGNID 122 Query: 109 ILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLG 168 IL++ A L + + S VS + + + GG V ++ Sbjct: 123 ILVHSLANGPEVTKPLLETSRKGYLAASSNSAYSFVSLLQHFGPIMNEGGSAVTLSYLAA 182 Query: 169 NRGQALQVH-AGSAKAAVDAMTRHLAVEWG-PQNIRVNSLAPGPISGTEGLR-----RLG 221 R SAKAA+++ TR LA E G +RVN+++ GP+ Sbjct: 183 ERVVPGYGGGMSSAKAALESDTRTLAWEAGQKYGVRVNAISAGPLKSRAASAIGKSGEKS 242 Query: 222 GPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVADGGAW 272 ++ +PL+R + ++ + L+L SPLA V+G L D G Sbjct: 243 FIDYAIDYSYNNAPLRRDLHSDDVGGAALFLLSPLARAVSGVTLYVDNGLH 293 >3DWF-A nrPDB Length = 276 Score = 131 bits (329), Expect = 5e-31, Method: Composition-based stats. Identities = 38/201 (18%), Positives = 69/201 (34%), Gaps = 3/201 (1%) Query: 21 FCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRC 80 F P++L+ K +TG GIG IA + G H V+ +RS + + Sbjct: 4 FRPEMLQGKKVIVTGASKGIGREIAYHLAKMGAHVVVTARSKEALQKVVARCLELGAASA 63 Query: 81 LPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSG 140 ++ + V +A G +D+LI + + M+++ Sbjct: 64 HYIAGSMEDMTFAEEFVAEAGNLMGGLDMLILNHVLYNRLTFFHGEIDNVRKSMEVNFHS 123 Query: 141 TFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQN 200 F V V G I +++ G L ++K A+D L E+ Sbjct: 124 -FVVLSVAAMPMLMQSQGSIAVVSSVAGKITYPLIAPYSASKFALDGFFSTLRSEFLVNK 182 Query: 201 IRVNSLAP--GPISGTEGLRR 219 + V+ G I ++ Sbjct: 183 VNVSITLCILGLIDTETAIKA 203 >3KZV-A nrPDB Length = 254 Score = 130 bits (328), Expect = 5e-31, Method: Composition-based stats. Identities = 43/189 (22%), Positives = 81/189 (42%), Gaps = 6/189 (3%) Query: 28 DKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDV 87 KV +TG GIG I ++ TV+ + R +KL G R + D+ Sbjct: 2 GKVILVTGVSRGIGKSIVDVLFSLDKDTVV--YGVARSEAPLKKLKEKYGDRFFYVVGDI 59 Query: 88 RAPPAVMAAVDQALKEFGRIDILINCAAG-NFLCPAGALSFNAFKTVMDIDTSGTFNVSR 146 + V+ A+K G+ID L+ A + + NA+K + DI+ ++ Sbjct: 60 TEDSVLKQLVNAAVKGHGKIDSLVANAGVLEPVQNVNEIDVNAWKKLYDINFFSIVSLVG 119 Query: 147 VLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSL 206 + + + + G +V +++ N + GS+KAA++ LA E + ++ ++ Sbjct: 120 IALPELKKTN-GNVVFVSSDACNMYFSSWGAYGSSKAALNHFAMTLANE--ERQVKAIAV 176 Query: 207 APGPISGTE 215 APG + Sbjct: 177 APGIVDTDM 185 >2DKN-A nrPDB Length = 255 Score = 130 bits (326), Expect = 8e-31, Method: Composition-based stats. Identities = 59/269 (21%), Positives = 92/269 (34%), Gaps = 52/269 (19%) Query: 30 VAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRA 89 V ITG SGIG + E+ R G + R + D+ Sbjct: 3 VIAITGSASGIGAALKELLARAGHTVIGIDRGQAD------------------IEADLST 44 Query: 90 PPAVMAAVDQALKEFGR-IDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVL 148 P AV L G +D L+ CA L V+ ++ G + L Sbjct: 45 PGGRETAVAAVLDRCGGVLDGLVCCAGVGVTAANSGL-------VVAVNYFGVSALLDGL 97 Query: 149 YEKFFRDHGGVIVNITATLGNRGQAL--------------------------QVHAGSAK 182 E R V + + + A + +K Sbjct: 98 AEALSRGQQPAAVIVGSIAATQPGAAELPMVEAMLAGDEARAIELAEQQGQTHLAYAGSK 157 Query: 183 AAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNK 242 AV + R V+W + +R+N +APG + P+ ST+ +PL R Sbjct: 158 YAVTCLARRNVVDWAGRGVRLNVVAPGAVETPLLQASKADPRYGESTRRFVAPLGRGSEP 217 Query: 243 TEIAHSVLYLASPLASYVTGAVLVADGGA 271 E+A ++ +L P AS++ G+VL DGG Sbjct: 218 REVAEAIAFLLGPQASFIHGSVLFVDGGM 246 >5PGZ-A nrPDB Length = 276 Score = 129 bits (325), Expect = 1e-30, Method: Composition-based stats. Identities = 37/204 (18%), Positives = 74/204 (36%), Gaps = 3/204 (1%) Query: 21 FCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRC 80 F P++L+ K +TG GIG +A + G H V+ +RS + + Sbjct: 11 FRPEMLQGKKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQKVVSRCLELGAASA 70 Query: 81 LPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSG 140 ++ + + +A K G +D+LI ++ + VM+++ Sbjct: 71 HYIAGTMEDMTFAEQFIVKAGKLMGGLDMLILNHITQTSLSLFHDDIHSVRRVMEVNFLS 130 Query: 141 TFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQN 200 +S + G I I++ G Q + ++K A+D + E Sbjct: 131 YVVMSTAALP-MLKQSNGSIAVISSLAGKMTQPMIAPYSASKFALDGFFSTIRTELYITK 189 Query: 201 IRVNSLAP--GPISGTEGLRRLGG 222 + V+ G I ++ + G Sbjct: 190 VNVSITLCVLGLIDTETAMKEISG 213 >2HRB-A nrPDB Length = 274 Score = 126 bits (317), Expect = 1e-29, Method: Composition-based stats. Identities = 48/237 (20%), Positives = 78/237 (32%), Gaps = 49/237 (20%) Query: 29 KVAFITGGGSGIGFRIAEIFMRH-GCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDV 87 +VA +TG GIG IA R V+ +R + R A ++L A G +D+ Sbjct: 3 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQL-QAEGLSPRFHQLDI 61 Query: 88 RAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRV 147 ++ A D KE+G +++L+N AA F + + + T N+ Sbjct: 62 DDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFATRNMCNE 121 Query: 148 LYEKFFRDHGGVIVNITATLGNRGQAL--------------------------------- 174 L G +VNI++ R Sbjct: 122 LLPIM--KPHGRVVNISSLQCLRAFENCSEDLQERFHSETLTEGDLVDLMKKFVEDTKNE 179 Query: 175 --------QVHAGSAKAAVDAMTRHLAVEWGPQ----NIRVNSLAPGPISGTEGLRR 219 G +K V ++R LA + I VN+ PGP+ + Sbjct: 180 VHEREGWPNSPYGVSKLGVTVLSRILARRLDEKRKADRILVNACCPGPVKTDMDGKD 236 >4HBG-A nrPDB Length = 286 Score = 125 bits (315), Expect = 2e-29, Method: Composition-based stats. Identities = 52/274 (18%), Positives = 99/274 (36%), Gaps = 50/274 (18%) Query: 30 VAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAA-------------RKLAGAT 76 VA +TG GIG I + + G +I + + A R+ A A Sbjct: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 Query: 77 GRRCLPLSMDVRAPPAVMAAVDQ--ALKEFGRI----------------DILINCAAGNF 118 + P +D + + D+ +++ + ++LINCA Sbjct: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 Query: 119 LCPAGALSFNAFKTVMDIDTSGTFNVSRVLYEKFFRDHGG-----------VIVNITAT- 166 + + + + +M+++ ++ + + + IVNI++ Sbjct: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 Query: 167 -LGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQA 225 G ++KAA+ T LA E P+NIR +++PG + GT+ ++ L Sbjct: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAK 245 Query: 226 SLSTKVTASPLQRLGN--KTEIAHSVLYLASPLA 257 + + + G EIA V L S A Sbjct: 246 EMLERT----IGASGTSAPAEIAEEVWSLYSRTA 275 >5L51-A nrPDB Length = 324 Score = 123 bits (308), Expect = 1e-28, Method: Composition-based stats. Identities = 54/291 (18%), Positives = 89/291 (30%), Gaps = 83/291 (28%) Query: 27 RDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTA----ARKLAGATGRRCLP 82 + A +TG GIGF I + G ++ASR R + A ++L G + Sbjct: 14 TKRYAVVTGANKGIGFEICKQLASKGITVILASRDEKRGIEARERLIKELGSEFGDYVVS 73 Query: 83 LSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGA------------------ 124 +DV P +V A VD +FG +DIL+N A N G Sbjct: 74 QQLDVADPASVAALVDFIKTKFGSLDILVNNAGLNGTYMEGDASVLNDYVEAEFKTFQSG 133 Query: 125 ----------------LSFNAFKTVMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLG 168 + K ++ + G+ V+ L + IVN+++TL Sbjct: 134 AAKTEPYHPKATGRLVETVEHAKECIETNYYGSKRVTEALIPLLQQSDSPRIVNVSSTLS 193 Query: 169 -------------------------------------------NRGQALQVHAGSAKAAV 185 + +KAA+ Sbjct: 194 SLVFQTNEWAKGVFSSEEGLTEEKLEEVLAEFLKDFIDGKQQEKQWPPHFSAYKVSKAAL 253 Query: 186 DAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPL 236 +A TR +A ++ R+N++ PG A + L Sbjct: 254 NAYTRIIAKKYPSF--RINAVCPGYTKTDLSYGHGQFTDAEAAEAPVKLAL 302 >1N5D-A nrPDB Length = 288 Score = 121 bits (305), Expect = 3e-28, Method: Composition-based stats. Identities = 51/234 (21%), Positives = 78/234 (33%), Gaps = 49/234 (20%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGC-HTVIASRSLPRVLTAARKLAGATGRRCLPLSMDV 87 +VA +TG GIGF I R V+ +R + R A ++L A G +D+ Sbjct: 5 RVALVTGANKGIGFAIVRDLCRQFAGDVVLTARDVARGQAAVKQL-QAEGLSPRFHQLDI 63 Query: 88 RAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRV 147 ++ A D KE+G +D+L+N AA F + M + GT NV Sbjct: 64 IDLQSIRALCDFLRKEYGGLDVLVNNAAIAFQLDNPTPFHIQAELTMKTNFMGTRNVCTE 123 Query: 148 LYEKFFRDHGGVIVNITATLGNRG------------------------------------ 171 L G +VN+++T G R Sbjct: 124 LLPLI--KPQGRVVNVSSTEGVRALNECSPELQQKFKSETITEEELVGLMNKFVEDTKNG 181 Query: 172 -----QALQVHAGSAKAAVDAMTRHLAVEW----GPQNIRVNSLAPGPISGTEG 216 G K V ++R A + I +N+ PG + G Sbjct: 182 VHRKEGWSDSTYGVTKIGVSVLSRIYARKLREQRAGDKILLNACCPGWVRTDMG 235 >3UCF-A nrPDB Length = 223 Score = 121 bits (303), Expect = 4e-28, Method: Composition-based stats. Identities = 60/247 (24%), Positives = 97/247 (39%), Gaps = 33/247 (13%) Query: 30 VAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRA 89 V + GG SGIG +A+ +ASR +D+ Sbjct: 8 VYVVLGGTSGIGAELAKQLESEHTIVHVASRQT---------------------GLDISD 46 Query: 90 PPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVLY 149 +V + G D LI A ++ + + DT V + Sbjct: 47 EKSVYHYFETI----GAFDHLIVTAG-SYAPAGKVVDVEVTQAKYAFDTKFWGAVLAAKH 101 Query: 150 EKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPG 209 + GG I + L + A + AA++A T+ LA E P IRVN+++PG Sbjct: 102 GARYLKQGGSITLTSGMLSRKVVANTYVKAAINAAIEATTKVLAKELAP--IRVNAISPG 159 Query: 210 PISGTEGLRRLGGPQASLSTKVTAS--PLQRLGNKTEIAHSVLYLASPLASYVTGAVLVA 267 ++ TE + + + T S P+ ++G ++IA + YL + SY+TG V+ Sbjct: 160 -LTKTEAYKGMNADDRDAMYQRTQSHLPVGKVGEASDIA--MAYLFAIQNSYMTGTVIDV 216 Query: 268 DGGAWLT 274 DGGA L Sbjct: 217 DGGALLG 223 >3O26-A nrPDB Length = 311 Score = 119 bits (299), Expect = 1e-27, Method: Composition-based stats. Identities = 52/315 (16%), Positives = 97/315 (30%), Gaps = 85/315 (26%) Query: 22 CPDLLRDK-VAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRC 80 CP+ + + A +TGG GIGF I + +G V+ R + + A KL + Sbjct: 5 CPNTVTKRRCAVVTGGNKGIGFEICKQLSSNGIMVVLTCRDVTKGHEAVEKLKNSNHENV 64 Query: 81 LPLSMDVRAP-PAVMAAVDQALKEFGRIDILINCAAGNFL-------------------- 119 + +DV P + + D FG++DIL+N A Sbjct: 65 VFHQLDVTDPIATMSSLADFIKTHFGKLDILVNNAGVAGFSVDADRFKAMISDIGEDSEE 124 Query: 120 ----------CPAGALSFNAFKTVMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGN 169 + ++ + + I+ +G +V+ VL IVN++++ G+ Sbjct: 125 LVKIYEKPEAQELMSETYELAEECLKINYNGVKSVTEVLIPLLQLSDSPRIVNVSSSTGS 184 Query: 170 R-------------------------------------------GQALQVHAGSAKAAVD 186 + ++KA ++ Sbjct: 185 LKYVSNETALEILGDGDALTEERIDMVVNMLLKDFKENLIETNGWPSFGAAYTTSKACLN 244 Query: 187 AMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIA 246 A TR LA + VN + PG + + V L + Sbjct: 245 AYTRVLANKIPKFQ--VNCVCPGLVKTEMNYGIGNYTAEEGAEHVVRIALF----PDD-- 296 Query: 247 HSVLYL--ASPLASY 259 + S L+++ Sbjct: 297 GPSGFFYDCSELSAF 311 >3U9L-A nrPDB Length = 324 Score = 118 bits (296), Expect = 3e-27, Method: Composition-based stats. Identities = 57/208 (27%), Positives = 85/208 (40%), Gaps = 6/208 (2%) Query: 24 DLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRS----LPRVLTAARKLAGATGRR 79 ++ K+ ITG SG G AE G + R + A A Sbjct: 1 MVMSKKIILITGASSGFGRLTAEALAGAGHRVYASMRDIVGRNASNVEAIAGFARDNDVD 60 Query: 80 CLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTS 139 L +DV++ +V A+DQ + E GRID+LI+ A PA A + F + DI+ Sbjct: 61 LRTLELDVQSQVSVDRAIDQIIGEDGRIDVLIHNAGHMVFGPAEAFTPEQFAELYDINVL 120 Query: 140 GTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQ-VHAGSAKAAVDAMTRHLAVEWGP 198 T V+R R G+++ I+++ G +AKAA+DA+ A E Sbjct: 121 STQRVNRAALPHMRRQKHGLLIWISSSSSAGGTPPYLAPYFAAKAAMDAIAVQYARELSR 180 Query: 199 QNIRVNSLAPG-PISGTEGLRRLGGPQA 225 I + + PG SGT G P Sbjct: 181 WGIETSIIVPGAFTSGTNHFAHSGVPDD 208 >2PTG-A nrPDB Length = 319 Score = 118 bits (296), Expect = 3e-27, Method: Composition-based stats. Identities = 59/305 (19%), Positives = 99/305 (32%), Gaps = 57/305 (18%) Query: 23 PDLLRDKVAFITGG--GSGIGFRIAEIFMRHGCHTVIASR-------------------- 60 P LR K AF+ G +G G+ I ++ G ++ + Sbjct: 4 PVDLRGKTAFVAGVADSNGYGWAICKLLRAAGARVLVGTWPPVYSIFKKGLESSRFEQDS 63 Query: 61 ------SLPRVLTAARKLAGATGRRCLPLSMDVRAPPAV------------------MAA 96 S AA K + PL P V Sbjct: 64 FYAQEPSSKVAAEAAEKPVDLVFDKIYPLDAVFDTPQDVPPEVSSNKRYAGVGGFTISEV 123 Query: 97 VDQALKEFGRIDILINC--AAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVLYEKFFR 154 + + G+IDIL++ P S + + + ++ + Sbjct: 124 AEAVRADVGQIDILVHSLANGPEVTKPLLQTSRKGYLAAVSSSSYSFVSLLQHFLPLM-- 181 Query: 155 DHGGVIVNITATLGNRGQALQVH-AGSAKAAVDAMTRHLAVEWGP-QNIRVNSLAPGPIS 212 GG + ++ + SAKAA+++ R LA E G + +RVN ++ GP+ Sbjct: 182 KEGGSALALSYIASEKVIPGYGGGMSSAKAALESDCRTLAFEAGRARAVRVNCISAGPLK 241 Query: 213 GTEGLR-----RLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVA 267 ++ +PLQ+ ++ + L+L SPLA VTGA L Sbjct: 242 SRAASAIGKAGDKTFIDLAIDYSEANAPLQKELESDDVGRAALFLLSPLARAVTGATLYV 301 Query: 268 DGGAW 272 D G Sbjct: 302 DNGLH 306 >3BHI-A nrPDB Length = 276 Score = 118 bits (295), Expect = 4e-27, Method: Composition-based stats. Identities = 59/282 (20%), Positives = 92/282 (32%), Gaps = 69/282 (24%) Query: 30 VAFITGGGSGIGFRIAEIFMRH-GCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVR 88 VA +TGG GIG I R V+ +R + R A ++L A G +D+ Sbjct: 6 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQL-QAEGLSPRFHQLDID 64 Query: 89 APPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVL 148 ++ A D KE+G +D+L+N A F + M + GT +V L Sbjct: 65 DLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVCTEL 124 Query: 149 YEKFFRDHGGVIVNITATLGNRG------------------------------------- 171 G +VN+++ + R Sbjct: 125 LPLI--KPQGRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTKKGV 182 Query: 172 ----QALQVHAGSAKAAVDAMTRHLAVEWGPQ----NIRVNSLAPGPISGTEGLRRLGGP 223 G K V ++R A + Q I +N+ PG + + GP Sbjct: 183 HQKEGWPSSAYGVTKIGVTVLSRIHARKLSEQRKGDKILLNACCPGWVRTD-----MAGP 237 Query: 224 QASLSTKVTASPLQRLGNKTEIAHSVLYLA--SPLASYVTGA 263 +A+ S E A + +YLA P A G Sbjct: 238 KATKS-------------PEEGAETPVYLALLPPDAEGPHGQ 266 >4OYR-A nrPDB Length = 289 Score = 116 bits (291), Expect = 1e-26, Method: Composition-based stats. Identities = 57/279 (20%), Positives = 105/279 (37%), Gaps = 28/279 (10%) Query: 14 LPAYRHLFCPDLLRDKVAFITGG--GSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARK 71 +P H+ LL K ++G S I F IA + G V+ L ++ Sbjct: 15 VPRGSHMT--GLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGF---DRLRLIQR 69 Query: 72 LAGATGRRCLPLSMDVRAPPAVMAAVDQALKEFG---RIDILINCAA-----GNFLCPAG 123 + + L +DV+ + + + + G ++D +++ G + P Sbjct: 70 ITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFF 129 Query: 124 ALSFNAFKTVMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKA 183 + + I ++++ L + GG IV + +R AK+ Sbjct: 130 DAPYADVSKGIHISAYSYASMAKALLPIM--NPGGSIVGM-DFDPSRAMPAYNWMTVAKS 186 Query: 184 AVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRLGG---------PQASLSTKVTAS 234 A++++ R +A E G +R N +A GPI +GG Q + Sbjct: 187 ALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRA 246 Query: 235 PLQR-LGNKTEIAHSVLYLASPLASYVTGAVLVADGGAW 272 P+ + + T +A +V L S TG ++ ADGGA Sbjct: 247 PIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAH 285 >1FJH-A nrPDB Length = 257 Score = 115 bits (289), Expect = 2e-26, Method: Composition-based stats. Identities = 51/270 (18%), Positives = 83/270 (30%), Gaps = 54/270 (20%) Query: 30 VAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRA 89 + I+G +GIG ++ G V + D+ Sbjct: 3 IIVISGCATGIGAATRKVLEAAGHQIVGIDIRDAE------------------VIADLST 44 Query: 90 PPAVMAAVDQALKEFG-RIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVL 148 A+ L + +D L+ CA V+ ++ G + Sbjct: 45 AEGRKQAIADVLAKCSKGMDGLVLCAGLGPQTKVL-------GNVVSVNYFGATELMDAF 97 Query: 149 YEKFFRDHGGVIVNITATLGNR----------------------------GQALQVHAGS 180 + H V I++ Q + Sbjct: 98 LPALKKGHQPAAVVISSVASAHLAFDKNPLALALEAGEEAKARAIVEHAGEQGGNLAYAG 157 Query: 181 AKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLG 240 +K A+ R A WG +R+N++APG L P+ S P+ R Sbjct: 158 SKNALTVAVRKRAAAWGEAGVRLNTIAPGATETPLLQAGLQDPRYGESIAKFVPPMGRRA 217 Query: 241 NKTEIAHSVLYLASPLASYVTGAVLVADGG 270 +E+A + +L SP ASYV GA +V DGG Sbjct: 218 EPSEMASVIAFLMSPAASYVHGAQIVIDGG 247 >2NTV-A nrPDB Length = 268 Score = 111 bits (277), Expect = 5e-25, Method: Composition-based stats. Identities = 56/269 (20%), Positives = 102/269 (37%), Gaps = 26/269 (9%) Query: 24 DLLRDKVAFITGG--GSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCL 81 LL K ++G S I F IA++ G V+ L +++A + Sbjct: 2 GLLEGKRILVSGIITDSSIAFHIAKVAQEAGAQLVLTGF---DRLRLIQRIADRLPDKAP 58 Query: 82 PLSMDVRAPPAVMAAVDQALKEFG---RIDILINCAAGNFLCPAG-----ALSFNAFKTV 133 + +DV+ + ++ E G ++D +++ G + Sbjct: 59 LIELDVQNEEHLATLAERVTAEIGEGNKLDGVVHSIGFMPQTGMGTNQFFDAPYEDVSKG 118 Query: 134 MDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLA 193 + I T ++++ L + GG IV + R AK+A++++ R +A Sbjct: 119 IHISTYSYASLAKALL--LIMNSGGSIVGM-DFDPTRAMPAYNWMTVAKSALESVNRFVA 175 Query: 194 VEWGPQNIRVNSLAPGPISGTEGLRRLGG---------PQASLSTKVTASPLQR-LGNKT 243 E G +R N +A GPI +GG Q +P+ + + T Sbjct: 176 REAGKYGVRSNLVAAGPIRTLAMSAIVGGAFGEEAGAQMQLLEEGWDQRAPIGWNMKDPT 235 Query: 244 EIAHSVLYLASPLASYVTGAVLVADGGAW 272 +A +V L S TG+++ ADGGA Sbjct: 236 PVAKTVCALLSEWLPATTGSIIYADGGAS 264 >3F4B-A nrPDB Length = 323 Score = 108 bits (270), Expect = 3e-24, Method: Composition-based stats. Identities = 49/309 (15%), Positives = 103/309 (33%), Gaps = 62/309 (20%) Query: 27 RDKVAFITGG--GSGIGFRIAEIFMRHGCHTV---------IASRSLPRVLTAARKLAGA 75 +++ FI G +G G+ IA+ + + I ++L + Sbjct: 6 ENEICFIAGVGDSNGYGWGIAKELSKRNVKVIFGVWPPVYNIFIKNLESGKFDKDMIINN 65 Query: 76 TGRR------CLPLSM-----DVRAPP-------------AVMAAVDQALKEFGRIDILI 111 + LPL D ++ + ++G+I +L+ Sbjct: 66 DNSKRMQILDVLPLDAGFDNYDDIDEDTKNNKRYNNLKNYSIEEVANLIYNKYGKISMLV 125 Query: 112 NC--AAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGN 169 + S + + + + ++ + + + GG +V++T Sbjct: 126 HSLANGREVQKSLLDTSRDGYLDAISKSSYSLISLCKHFCKFM--NSGGSVVSLTYQASQ 183 Query: 170 RGQALQVH-AGSAKAAVDAMTRHLAVEWG-PQNIRVNSLAPGPISGTEGL---------- 217 + SAKAA+++ TR LA G NIR+N+++ GP+ Sbjct: 184 KVVPGYGGGMSSAKAALESDTRVLAYYLGRKYNIRINTISAGPLKSRAATAINKFNNNQK 243 Query: 218 -----------RRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLV 266 + ++ +PL++ T++ +L S +S VTG + Sbjct: 244 NNMNSSGETDKQNYSFIDYAIDYSEKYAPLKKKLLSTDVGSVASFLLSKESSAVTGQTIY 303 Query: 267 ADGGAWLTF 275 D G + F Sbjct: 304 VDNGLNIMF 312 >5LCX-A nrPDB Length = 316 Score = 100 bits (249), Expect = 8e-22, Method: Composition-based stats. Identities = 47/274 (17%), Positives = 83/274 (30%), Gaps = 85/274 (31%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGAT---GRRCLPLSM 85 + A +TG GIGF I G ++ SR+ R L A +KL R + + Sbjct: 8 RYALVTGANKGIGFEICRQLAEKGIIVILTSRNEKRGLEARQKLLKELNVSENRLVFHQL 67 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSF------------------ 127 DV +V A +FG++DIL+N A + + G +S Sbjct: 68 DVTDLASVAAVAVFIKSKFGKLDILVNNAGVSGVEMVGDVSVFNEYIEADFKALQALEAG 127 Query: 128 -------------------NAFKTVMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLG 168 K + + G +++ L IVN++++ G Sbjct: 128 AKEEPPFKPKANGEMIEKFEGAKDCVVTNYYGPKRLTQALIPLLQLSPSPRIVNVSSSFG 187 Query: 169 N-------------------------------------------RGQALQVHAGSAKAAV 185 + + +KAA+ Sbjct: 188 SLLLLWNEWAKGVLGDEDRLTEERVDEVVEVFLKDIKEGKLEESQWPPHFAAERVSKAAL 247 Query: 186 DAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRR 219 +A T+ A ++ R+N++ PG Sbjct: 248 NAYTKIAAKKYPSF--RINAICPGYAKTDITFHA 279 >1SNY-A nrPDB Length = 267 Score = 96.5 bits (239), Expect = 1e-20, Method: Composition-based stats. Identities = 40/250 (16%), Positives = 83/250 (33%), Gaps = 31/250 (12%) Query: 14 LPAYRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGC---HTVIASRSLPRVLTAAR 70 +P H+ ITG G+G + + + H R+ + Sbjct: 15 VPRGSHMNS--------ILITGCNRGLGLGLVKALLNLPQPPQHLFTTCRNREQAKELED 66 Query: 71 KLAGATGRRCLPLSMDVRAPPAVMAAVDQA--LKEFGRIDILINCAAGNF-LCPAGALSF 127 L +D+R A V + + +++L N A A+ Sbjct: 67 --LAKNHSNIHILEIDLRNFDAYDKLVADIEGVTKDQGLNVLFNNAGIAPKSARITAVRS 124 Query: 128 NAFKTVMDIDTSGTFNVSRVLYEKFFRD-----------HGGVIVNITATLGNRGQ---A 173 + +T +++ + I+N+++ LG+ Sbjct: 125 QELLDTLQTNTVVPIMLAKACLPLLKKAAKANESQPMGVGRAAIINMSSILGSIQGNTDG 184 Query: 174 LQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTA 233 ++K+A++A T+ L+V+ PQ I SL PG + G + + ++ Sbjct: 185 GMYAYRTSKSALNAATKSLSVDLYPQRIMCVSLHPGWVKTDMGGSSAPLDVPTSTGQIVQ 244 Query: 234 SPLQRLGNKT 243 + + +LG K Sbjct: 245 T-ISKLGEKQ 253 >1B15-A nrPDB Length = 254 Score = 95.4 bits (236), Expect = 3e-20, Method: Composition-based stats. Identities = 38/217 (17%), Positives = 71/217 (32%), Gaps = 16/217 (7%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 L +K GIG + ++ + + A A + Sbjct: 3 LTNKNVIFVAALGGIGLDTSRELVKRNLKNFVILDRVENPTALAELKAINPKVNITFHTY 62 Query: 86 DVRAP-PAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNV 144 DV P + + + +DILIN A L + + + I+ +G N Sbjct: 63 DVTVPVAESKKLLKKIFDQLKTVDILINGAGI--------LDDHQIERTIAINFTGLVNT 114 Query: 145 SRVLYEKFFRDHGG---VIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGP-QN 200 + + + + + GG +I NI + G ++KAAV + T LA P Sbjct: 115 TTAILDFWDKRKGGPGGIIANICSVTGFNAIHQVPVYSASKAAVVSFTNSLAK-LAPITG 173 Query: 201 IRVNSLAPGPISGTE--GLRRLGGPQASLSTKVTASP 235 + S+ PG + ++ + + P Sbjct: 174 VTAYSINPGITRTPLVHTFNSWLDVEPRVAELLLSHP 210 >2O2Y-A nrPDB Length = 349 Score = 92.7 bits (229), Expect = 2e-19, Method: Composition-based stats. Identities = 43/327 (13%), Positives = 92/327 (28%), Gaps = 85/327 (25%) Query: 35 GGGSGIGFRIAEIFMRHGCHTVIA------------------SRSLPRVLTAARKLAGAT 76 G +G G+ IA+ + + + + Sbjct: 23 GDTNGYGWGIAKELSKRNVKIIFGIWPPVYNIFMKNYKNGKFDNDMIIDKDKKMNILDML 82 Query: 77 GRRCLPLSMDVRAPPA-------------VMAAVDQALKEFGRIDILINCAAGNFLCPAG 123 + + + + +++G+I++L++ A Sbjct: 83 PFDASFDTANDIDEETKNNKRYNMLQNYTIEDVANLIHQKYGKINMLVHSLANAKEVQKD 142 Query: 124 AL--SFNAFKTVMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVH-AGS 180 L S + + + ++ + I+++T + S Sbjct: 143 LLNTSRKGYLDALSKSSYSLISLCKYFVNIM--KPQSSIISLTYHASQKVVPGYGGGMSS 200 Query: 181 AKAAVDAMTRHLAVEWGP-QNIRVNSLAPGPISGTEGL---------------------- 217 AKAA+++ TR LA G NIR+N+++ GP+ Sbjct: 201 AKAALESDTRVLAYHLGRNYNIRINTISAGPLKSRAATAINKLNNTYENNTNQNKNRNSH 260 Query: 218 --------------------RRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLA 257 + ++ +PL++ T+I +L S + Sbjct: 261 DVHNIMNNSGEKEEKKNSASQNYTFIDYAIEYSEKYAPLRQKLLSTDIGSVASFLLSRES 320 Query: 258 SYVTGAVLVADGGAWLTFPNGVKGLPD 284 +TG + D G + F LPD Sbjct: 321 RAITGQTIYVDNGLNIMF------LPD 341 >1MG5-A nrPDB Length = 255 Score = 91.5 bits (226), Expect = 3e-19, Method: Composition-based stats. Identities = 39/220 (17%), Positives = 71/220 (32%), Gaps = 16/220 (7%) Query: 23 PDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLP 82 L +K G GIG ++ ++ ++ + A A Sbjct: 1 SFTLTNKNVIFVAGLGGIGLDTSKELLKRDLKNLVILDRIENPAAIAELKAINPKVTVTF 60 Query: 83 LSMDVRAP-PAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGT 141 DV P + + +D+LIN A L + + + ++ +G Sbjct: 61 YPYDVTVPIAETTKLLKTIFAQLKTVDVLINGAGI--------LDDHQIERTIAVNYTGL 112 Query: 142 FNVSRVLYEKFFRDHGG---VIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGP 198 N + + + + + GG +I NI + G KAAV T LA P Sbjct: 113 VNTTTAILDFWDKRKGGPGGIICNIGSVTGFNAIYQVPVYSGTKAAVVNFTSSLAK-LAP 171 Query: 199 -QNIRVNSLAPGPISGTE--GLRRLGGPQASLSTKVTASP 235 + ++ PG T + ++ K+ A P Sbjct: 172 ITGVTAYTVNPGITRTTLVHKFNSWLDVEPQVAEKLLAHP 211 >4Z3K-A nrPDB Length = 275 Score = 87.3 bits (215), Expect = 6e-18, Method: Composition-based stats. Identities = 42/215 (19%), Positives = 84/215 (39%), Gaps = 20/215 (9%) Query: 18 RHLFCPDL---LRDKVAFITGGGSGIGF---RIAEIFMRHGCHTVIASRSLPRVLTAARK 71 +L+ + L V +TG G G + + G V+++R+ + + Sbjct: 8 ENLYFQGMEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAE 67 Query: 72 L-AGATGRRCLPLSMDVRAPPAVMAAVDQALK-----EFGRIDILINCAAGNFLCPAGAL 125 L A +G R + + D+ A + + + R+ +LIN A G + Sbjct: 68 LGAERSGLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRL-LLINNAGSLGDVSKGFV 126 Query: 126 SFNAFKTVMD---IDTSGTFNVSRVLYEKFFRDHG--GVIVNITATLGNRGQALQVHAGS 180 + V + ++ + ++ + + F G +VNI++ + + Sbjct: 127 DLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCA 186 Query: 181 AKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTE 215 KAA D + + LA+E N+RV + APGP+ Sbjct: 187 GKAARDMLFQVLALE--EPNVRVLNYAPGPLDTDM 219 >4HWK-A nrPDB Length = 288 Score = 86.1 bits (212), Expect = 1e-17, Method: Composition-based stats. Identities = 40/200 (20%), Positives = 79/200 (39%), Gaps = 17/200 (8%) Query: 30 VAFITGGGSGIGF---RIAEIFMRHGCHTVIASRSLPRVLTAARKL-AGATGRRCLPLSM 85 V +TG G G + + G V+++R+ + +L A +G R + + Sbjct: 36 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 95 Query: 86 DVRAPPAVMAAVDQALK-----EFGRIDILINCAAGNFLCPAGALSFNAFKTVMD---ID 137 D+ A + + + R+ +LIN A G + + V + ++ Sbjct: 96 DLGAEAGLQQLLGALRELPRPKGLQRL-LLINNAGSLGDVSKGFVDLSDSTQVNNYWALN 154 Query: 138 TSGTFNVSRVLYEKFFRDHG--GVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVE 195 + ++ + + F G +VNI++ + + KAA D + + LA+E Sbjct: 155 LTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE 214 Query: 196 WGPQNIRVNSLAPGPISGTE 215 N+RV + APGP+ Sbjct: 215 --EPNVRVLNYAPGPLDTDM 232 >1OAA-A nrPDB Length = 259 Score = 85.8 bits (211), Expect = 2e-17, Method: Composition-based stats. Identities = 43/200 (21%), Positives = 76/200 (38%), Gaps = 17/200 (8%) Query: 30 VAFITGGGSGIGFRIAEIFMRH---GCHTVIASRSLPRVLTAARKL-AGATGRRCLPLSM 85 V +TG G G +A R G ++++RS + +L A + + + Sbjct: 8 VCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKVVLAAA 67 Query: 86 DVRAPPAVMAAVDQALK-----EFGRIDILINCAAGNFLCPAGALSFNAFKTVMD---ID 137 D+ V + + R+ +LIN AA G L+ N V + ++ Sbjct: 68 DLGTEAGVQRLLSAVRELPRPEGLQRL-LLINNAATLGDVSKGFLNVNDLAEVNNYWALN 126 Query: 138 TSGTFNVSRVLYEKFFRDHG--GVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVE 195 + ++ F G +VNI++ + + KAA D + + LA E Sbjct: 127 LTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQVLAAE 186 Query: 196 WGPQNIRVNSLAPGPISGTE 215 ++RV S APGP+ Sbjct: 187 --EPSVRVLSYAPGPLDNDM 204 >5TQV-A nrPDB Length = 233 Score = 84.6 bits (208), Expect = 5e-17, Method: Composition-based stats. Identities = 40/214 (18%), Positives = 84/214 (39%), Gaps = 18/214 (8%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVR 88 K I G G+G + R G + + +R LA ++D+ Sbjct: 10 KTVLIVGASRGLGREFVRQYQRDGWNVIATARDDAS-------LAALRALGAHAHALDIT 62 Query: 89 APPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVL 148 P + A + E + ++++ G ++ + F TVM + G + +L Sbjct: 63 QPEQIAALGWKLDGERLDVAVVVSGVYGPRTEGVETIASDDFDTVMHTNVRGPMQLLPIL 122 Query: 149 YEKFFRDHGGVIVNITATLGNRGQALQVH---AGSAKAAVDAMTRHLAVEWGPQNIRVNS 205 D GV+ +++ +G+ +A ++KAA++ + R + ++ S Sbjct: 123 LP-LVEDARGVLAVVSSRMGSISEATGTTGWLYRASKAALNDVLRIAS--LQTRHAACIS 179 Query: 206 LAPGPISGTEGLRRLGGPQASLSTKVTASPLQRL 239 L PG + +GG QA+L + + ++R+ Sbjct: 180 LHPGWVRTD-----MGGAQAALDPATSVTGMRRV 208 >5WQO-A nrPDB Length = 234 Score = 83.8 bits (206), Expect = 7e-17, Method: Composition-based stats. Identities = 43/223 (19%), Positives = 82/223 (36%), Gaps = 17/223 (7%) Query: 31 AFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAP 90 I G GIG +A+ F++ G +R P+ + LA G R ++ D+ Sbjct: 9 VLIVGASRGIGLGLADAFLQRGAQVFAVARR-PQGSPGLQALAERAGERLQAVTGDLNQH 67 Query: 91 PAVMAAVDQALKEFGRIDILINCAAGNFL--CPAGALSFNAFKTVMDIDTSGTFNVSRVL 148 + + RID LI A + + + ++R L Sbjct: 68 DCAERIGEMLGER--RIDRLIVNAGIYGPQQQDVAEIDAEQTAQLFLTNAIAPLRLARAL 125 Query: 149 YEKFFRDHGGVIVNITATLGNRGQALQVH---AGSAKAAVDAMTRHLAVEWGPQNIRVNS 205 + GGV+ +++ + + L G++KAA++++ R E+ + Sbjct: 126 SGRV--SRGGVVAFMSSQMASLALGLSATMPLYGASKAALNSLVRSWEGEFEELPFSLLL 183 Query: 206 LAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHS 248 L PG + +GG A LS + +A+ + + A Sbjct: 184 LHPGWVRT-----EMGGDSAPLSVEESAA--GLVAAVEDAAGV 219 >4LIS-A nrPDB Length = 371 Score = 75.7 bits (185), Expect = 2e-14, Method: Composition-based stats. Identities = 30/171 (17%), Positives = 54/171 (31%), Gaps = 27/171 (15%) Query: 31 AFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAP 90 +TGG IG + G V+A A ++ +G++ +DV Sbjct: 6 VLVTGGTGYIGSFTTLALLEAGYKVVVADNLYNSSAEALNRIELISGKKAEFAQLDVTDE 65 Query: 91 PAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVLYE 150 AA D+ + ID +I+ AA + +G + ++ GT L Sbjct: 66 ----AAFDKVFEAHPDIDSVIHFAALKAVGESGEKPLDY----YHVNVYGTI----CLLR 113 Query: 151 KFFRDHGGVIVNITATLGNR---------------GQALQVHAGSAKAAVD 186 R + IV ++ G+ K A++ Sbjct: 114 SMVRHNVTNIVFSSSATVYGDATRFPDMIPIPEHCPLGPTNPYGNTKFAIE 164 >3SLK-A nrPDB Length = 795 Score = 71.5 bits (174), Expect = 4e-13, Method: Composition-based stats. Identities = 35/186 (18%), Positives = 63/186 (33%), Gaps = 22/186 (11%) Query: 30 VAFITGGGSGIGFRIAEIFM-RHGCH-TVIASRSLPRVLTAARKLAG--ATGRRCLPLSM 85 +TGG +G +A + G V+ SR P AA +A A G + Sbjct: 532 TVLVTGGTGALGAEVARHLVIERGVRNLVLVSRRGPAASGAAELVAQLTAYGAEVSLQAC 591 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 DV + + E + +++ A + +L+ V+ G N+ Sbjct: 592 DVADRETLAKVLASIPDEH-PLTAVVHAAGVLDDGVSESLTVERLDQVLRPKVDGARNLL 650 Query: 146 RVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAM----------TRHLAVE 195 ++ +V ++ G G Q + +A + +DA+ TR LA Sbjct: 651 ELIDPDV------ALVLFSSVSGVLGSGGQGNYAAANSFLDALAQQRQSRGLPTRSLAWG 704 Query: 196 -WGPQN 200 W Sbjct: 705 PWAEHG 710 >3ORF-A nrPDB Length = 251 Score = 68.0 bits (165), Expect = 5e-12, Method: Composition-based stats. Identities = 29/212 (13%), Positives = 68/212 (32%), Gaps = 25/212 (11%) Query: 14 LPAYRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLA 73 +P H+ K + GG +G + + F +T+ + + Sbjct: 15 VPRGSHM-------SKNILVLGGSGALGAEVVKFFKSKSWNTISIDFRENPNADHSFTIK 67 Query: 74 GATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAG-ALSFNAFKT 132 + + +++ + ++D + A G A + K Sbjct: 68 D-------------SGEEEIKSVIEKINSKSIKVDTFVCAAGGWSGGNASSDEFLKSVKG 114 Query: 133 VMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHL 192 ++D++ F + + + + GG+ V A+ + + G+ KAA + + L Sbjct: 115 MIDMNLYSAFASAHIGAKLL--NQGGLFVLTGASAALNRTSGMIAYGATKAATHHIIKDL 172 Query: 193 AVEWG--PQNIRVNSLAPGPISGTEGLRRLGG 222 A E G P + P + + + Sbjct: 173 ASENGGLPAGSTSLGILPVTLDTPTNRKYMSD 204 >1I3M-A nrPDB Length = 348 Score = 57.2 bits (137), Expect = 8e-09, Method: Composition-based stats. Identities = 29/187 (15%), Positives = 61/187 (32%), Gaps = 34/187 (18%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIAS------RSLPRVLTAARKLAGATGRR 79 + +KV +TGG IG + G V+ R + + R++ TGR Sbjct: 1 MAEKV-LVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRS 59 Query: 80 CLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTS 139 MD+ A+ + +I+ A + + + ++ ++ + Sbjct: 60 VEFEEMDILDQGALQRLFKKY-----SFMAVIHFAGLKAMGESVQKPLDYYR----VNLT 110 Query: 140 GTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQ-------------VHAGSAKAAVD 186 GT + + + HG + +++ G G +K ++ Sbjct: 111 GTIQLL-----EIMKAHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIE 165 Query: 187 AMTRHLA 193 M R L Sbjct: 166 EMIRDLC 172 >2PK3-A nrPDB Length = 321 Score = 57.2 bits (137), Expect = 9e-09, Method: Composition-based stats. Identities = 39/260 (15%), Positives = 78/260 (30%), Gaps = 43/260 (16%) Query: 31 AFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAP 90 A ITG +G +A SR+ L ++ +D+ Sbjct: 15 ALITGVAGFVGKYLANHLTEQNVEVFGTSRNNEAKLPNVEMIS-----------LDIMDS 63 Query: 91 PAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNV------ 144 V + + D + + AA + + S+ K + GT +V Sbjct: 64 QRVKKVISDI-----KPDYIFHLAAKSSVKD----SWLNKKGTFSTNVFGTLHVLDAVRD 114 Query: 145 ----SRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQN 200 R+L ++G ++ + G +KA+V + R +G Sbjct: 115 SNLDCRILTIGSSEEYGMILPEESPVSEENQLRPMSPYGVSKASVGMLARQYVKAYGMDI 174 Query: 201 I---RVNSLAPGP---ISGTEGLRRLGGPQASLSTKVTAS----PLQRLGNKTEIAHSVL 250 I N + PG + +++ + + ++ + +I + Sbjct: 175 IHTRTFNHIGPGQSLGFVTQDFAKQIVDIEMEKQEPIIKVGNLEAVRDFTDVRDIVQAY- 233 Query: 251 YLASPLASYVTGAVLVADGG 270 +L S TG V G Sbjct: 234 WLLSQYGK--TGDVYNVCSG 251 >1Z45-A nrPDB Length = 699 Score = 56.1 bits (134), Expect = 2e-08, Method: Composition-based stats. Identities = 25/176 (14%), Positives = 50/176 (28%), Gaps = 28/176 (15%) Query: 27 RDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMD 86 K+ +TGG IG + +G V+A + +L T +D Sbjct: 10 TSKIVLVTGGAGYIGSHTVVELIENGYDCVVADNLSNSTYDSVARLEVLTKHHIPFYEVD 69 Query: 87 VRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSR 146 + + + +ID +I+ A + + + + + GT Sbjct: 70 LCDRKGLEKVFKEY-----KIDSVIHFAGLKAVGESTQIPLRYYHN----NILGTV---- 116 Query: 147 VLYEKFFRDHGGVIVNITATLGNR---------------GQALQVHAGSAKAAVDA 187 VL E + + V ++ G K A++ Sbjct: 117 VLLELMQQYNVSKFVFSSSATVYGDATRFPNMIPIPEECPLGPTNPYGHTKYAIEN 172 >3ENK-A nrPDB Length = 341 Score = 53.8 bits (128), Expect = 8e-08, Method: Composition-based stats. Identities = 18/70 (25%), Positives = 25/70 (35%) Query: 30 VAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRA 89 +TGG IG A + HG VIA + A ++ TG+ DV Sbjct: 7 TILVTGGAGYIGSHTAVELLAHGYDVVIADNLVNSKREAIARIEKITGKTPAFHETDVSD 66 Query: 90 PPAVMAAVDQ 99 A+ D Sbjct: 67 ERALARIFDA 76 >1UDA-A nrPDB Length = 338 Score = 53.4 bits (127), Expect = 1e-07, Method: Composition-based stats. Identities = 22/169 (13%), Positives = 49/169 (28%), Gaps = 25/169 (14%) Query: 31 AFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAP 90 +TGG IG +++G +I + + G+ + D+R Sbjct: 3 VLVTGGSGYIGSHTCVQLLQNGHDVIILDNLCNSKRSVLPVIERLGGKHPTFVEGDIRNE 62 Query: 91 PAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVLYE 150 A + + L + ID +I+ A + + + + +GT + Sbjct: 63 ----ALMTEILHDH-AIDTVIHFAGLKAVGESVQKPLEYYDN----NVNGTLRLISA--- 110 Query: 151 KFFRDHGGVIVNITATLGNRGQAL------------QVHAGSAKAAVDA 187 + + ++ Q G +K V+ Sbjct: 111 -MRAANVKNFIFSSSATVYGDNPKIPYVESFPTGTPQSPYGKSKLMVEQ 158 >4G5H-A nrPDB Length = 363 Score = 53.4 bits (127), Expect = 1e-07, Method: Composition-based stats. Identities = 28/173 (16%), Positives = 53/173 (30%), Gaps = 24/173 (13%) Query: 14 LPAYRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLA 73 +P + DK+ ITGG G + + F+ + + RK Sbjct: 15 VPRGSAM----GFDDKILLITGGTGSFGNAVMKRFLDSNIKEIRIFSRDEKKQDDIRK-- 68 Query: 74 GATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTV 133 + DVR +V A+ +D + + AA + A K Sbjct: 69 KYNNSKLKFYIGDVRDSQSVETAMRD-------VDYVFHAAALKQVPSCEFFPVEAVK-- 119 Query: 134 MDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVD 186 + GT NV + + + + ++ G +KA ++ Sbjct: 120 --TNIIGTENVLQSAIHQNVKK-------VICLSTDKAAYPINAMGISKAMME 163 >2Q1W-A nrPDB Length = 333 Score = 51.9 bits (123), Expect = 3e-07, Method: Composition-based stats. Identities = 31/217 (14%), Positives = 62/217 (28%), Gaps = 43/217 (19%) Query: 14 LPAYRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLA 73 +P H+ K FITG IG IAE+ + G V R+ Sbjct: 15 VPRGSHM--------KKVFITGICGQIGSHIAELLLERGDKVVGID-----NFATGRREH 61 Query: 74 GATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTV 133 + + V + + D +++ AA + + Sbjct: 62 LKDHPNLTFVEGSIADHALVNQLIGDL-----QPDAVVHTAASYK-------DPDDWYND 109 Query: 134 MDIDTSGTFNVSRVLYEKFFRDHGGVIVNI--TATLGNRG-----------QALQVHAGS 180 + G NV + +++ G V G + Sbjct: 110 TLTNCVGGSNVVQAA----KKNNVGRFVYFQTALCYGVKPIQQPVRLDHPRNPANSSYAI 165 Query: 181 AKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGL 217 +K+A + + +++ + N + P +SG + Sbjct: 166 SKSANEDYLEYSGLDFVTFRL-ANVVGPRNVSGPLPI 201 >1OOE-A nrPDB Length = 236 Score = 50.7 bits (120), Expect = 8e-07, Method: Composition-based stats. Identities = 31/203 (15%), Positives = 61/203 (30%), Gaps = 19/203 (9%) Query: 27 RDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMD 86 KV + GG +G I E F ++G + S + + + + Sbjct: 3 SGKV-IVYGGKGALGSAILEFFKKNGYTVLNIDLSANDQADSN-----------ILVDGN 50 Query: 87 VRAPPAVMAAVDQALKEFGR--IDILINCAAGNFLCPAGALS-FNAFKTVMDIDTSGTFN 143 + ++Q +D + A G A + ++ + Sbjct: 51 KNWTEQEQSILEQTASSLQGSQVDGVFCVAGGWAGGSASSKDFVKNADLMIKQSVWSSAI 110 Query: 144 VSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAV--EWGPQNI 201 +++ GG++ A + G AKAAV +T LA P N Sbjct: 111 AAKLATTHL--KPGGLLQLTGAAAAMGPTPSMIGYGMAKAAVHHLTSSLAAKDSGLPDNS 168 Query: 202 RVNSLAPGPISGTEGLRRLGGPQ 224 V ++ P + + + Sbjct: 169 AVLTIMPVTLDTPMNRKWMPNAD 191 >1DIR-A nrPDB Length = 241 Score = 50.3 bits (119), Expect = 1e-06, Method: Composition-based stats. Identities = 30/207 (14%), Positives = 59/207 (28%), Gaps = 26/207 (12%) Query: 27 RDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMD 86 + + GG +G R + F +A+ + + M Sbjct: 6 EARRVLVYGGRGALGSRCVQAFRARNWWVASIDVVENEEASAS-----------VIVKMT 54 Query: 87 VRAPPAVMAAVDQALKEFG--RIDILINCAAGNFLCPAGALS-----FNAFKTVMDIDTS 139 + K G ++D ++ A G A + S +K + T Sbjct: 55 DSFTEQADQVTAEVGKLLGDQKVDAILCVAGGWAGGNAKSKSLFKNCDLMWKQSIWTSTI 114 Query: 140 GTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLA--VEWG 197 + ++ L GG++ A G + G AK AV + + LA Sbjct: 115 SSHLATKHL------KEGGLLTLAGAKAALDGTPGMIGYGMAKGAVHQLCQSLAGKNSGM 168 Query: 198 PQNIRVNSLAPGPISGTEGLRRLGGPQ 224 P ++ P + + + Sbjct: 169 PSGAAAIAVLPVTLDTPMNRKSMPEAD 195 >6BWL-A nrPDB Length = 328 Score = 50.3 bits (119), Expect = 1e-06, Method: Composition-based stats. Identities = 41/263 (15%), Positives = 78/263 (29%), Gaps = 43/263 (16%) Query: 32 FITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAPP 91 +TGG IG + + ++ I + A + + D++ Sbjct: 4 LVTGGAGFIGRWVVKRLLQDKHEVWILDNLANSTTANITEFAHDLNLKQC-IQGDIKDKK 62 Query: 92 AVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVLYEK 151 V + D+ + AA + S + + + DT GTFN+ Sbjct: 63 LVAQLFEN-----NSFDLCYHLAASINVQD----SIDDARATFENDTIGTFNLLEQCLNY 113 Query: 152 ----------FFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNI 201 D I I+ + +K A + M + + Sbjct: 114 DVKMVFMSTCMVYDKATNIQGISELDPIKPA---SPYAGSKIAAENMVLSY---YYAYKL 167 Query: 202 RVNSLAP----GPISGTEGLRRLGGPQASLSTKVTASPLQRLGN---------KTEIAHS 248 V + P GP T G + ++ K+ PL G+ + A Sbjct: 168 PVVVIRPFNTYGPFQKTGGEGGVVAI--FINNKLDNVPLNIYGDGKQTRDLLYVEDCADF 225 Query: 249 VLYLASPLASYVTGAVLVADGGA 271 V+ A+ ++ G ++ A G Sbjct: 226 VV--AAGYSAKANGHIINAGTGQ 246 >4J2O-A nrPDB Length = 363 Score = 49.9 bits (118), Expect = 1e-06, Method: Composition-based stats. Identities = 42/247 (17%), Positives = 77/247 (31%), Gaps = 40/247 (16%) Query: 14 LPAYRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCH-TVIASRSLPRVLTAARKL 72 +P + +DKV ITGG G + + F+ I SR + +K Sbjct: 15 VPRGS------MFKDKVLLITGGTGSFGNAVLKRFLETDIKEIRIFSRDEKKQDDMRKKY 68 Query: 73 AGATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKT 132 A + DVR +++ A +D + + AA + A K Sbjct: 69 HSA---KLKFYIGDVRDYNSILNATR-------GVDYIYHAAALKQVPSCEFHPMEAVK- 117 Query: 133 VMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHL 192 + GT NV E ++H +V ++ G +KA ++ + Sbjct: 118 ---TNVLGTENV----LEAAIQNHVKRVVCLSTDKAVYPI---NAMGISKAMMEKVMVAK 167 Query: 193 AVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPL--------QRLGNKTE 244 + ++++ G G R + PL + + + Sbjct: 168 SRNLEG----LDTVICGTRYGNVMASRGSVIPLFVDQIRQGKPLTITDPNMTRFMMTLED 223 Query: 245 IAHSVLY 251 VLY Sbjct: 224 AVDLVLY 230 >2GN9-A nrPDB Length = 344 Score = 49.5 bits (117), Expect = 2e-06, Method: Composition-based stats. Identities = 25/161 (15%), Positives = 45/161 (27%), Gaps = 21/161 (13%) Query: 23 PDLLRDKVAFITGGGSGIGFRIAEI-FMRHGCHTVIASRSLPRVLTAARKLAGATGRRCL 81 ++L ++ ITGG G +I L + R Sbjct: 16 QNMLDNQTILITGGTGSFGKCFVRKVLDTTNAKKIIVYSRDE--LKQSEMAMEFNDPRMR 73 Query: 82 PLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGT 141 DVR + A++ +DI I+ AA + A + + G Sbjct: 74 FFIGDVRDLERLNYALE-------GVDICIHAAALKHVPIAEYNPLE----CIKTNIMGA 122 Query: 142 FNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAK 182 NV + ++ ++ L G+ K Sbjct: 123 SNVINACLKNAISQ----VIALSTDKAANPINL---YGATK 156 >3RFT-A nrPDB Length = 267 Score = 46.8 bits (110), Expect = 1e-05, Method: Composition-based stats. Identities = 25/174 (14%), Positives = 46/174 (26%), Gaps = 41/174 (23%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVR 88 K +TG +G + E +A S G + D+ Sbjct: 4 KRLLVTGAAGQLGRVMRERLAPMAEILRLADLSP----------LDPAGPNEECVQCDLA 53 Query: 89 APPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVL 148 AV A V D +++ + P F+ ++ + G +N+ Sbjct: 54 DANAVNAMVA-------GCDGIVHLGGISVEKP--------FEQILQGNIIGLYNL---- 94 Query: 149 YEKFFRDHGGVIVNITATLGNRGQALQ------------VHAGSAKAAVDAMTR 190 YE IV ++ G +K + + R Sbjct: 95 YEAARAHGQPRIVFASSNHTIGYYPQTERLGPDVPARPDGLYGVSKCFGENLAR 148 >4R1T-A nrPDB Length = 337 Score = 46.1 bits (108), Expect = 2e-05, Method: Composition-based stats. Identities = 21/153 (13%), Positives = 42/153 (27%), Gaps = 20/153 (13%) Query: 25 LLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLS 84 + +V +TG G I + +I + G R+ + R Sbjct: 7 SVSGQVVCVTGAGGFIASWLVKILLEKGYTVRGTVRNPDDPKNGHLRELEGAKERLTLCK 66 Query: 85 MDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNV 144 D+ ++ A++ D + + A+ P + GT NV Sbjct: 67 ADLLDYQSLREAIN-------GCDGVFHTASPVTDDPEQMVEPA---------VIGTKNV 110 Query: 145 SRVLYEKFFRDHGGVIVNITATLGNRGQALQVH 177 E R +V ++ + Sbjct: 111 INAAAEANVR----RVVFTSSIGAVYMDPNRDP 139 >3SXP-A nrPDB Length = 362 Score = 45.7 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 33/207 (15%), Positives = 61/207 (29%), Gaps = 42/207 (20%) Query: 24 DLLRDKVAFITGGGSGIGFRIAEIFMRHG--CHTVIASR---------SLPRVLTAARKL 72 D L ++ ITGG +G +A F + V+ + + P L + L Sbjct: 6 DELENQTILITGGAGFVGSNLAFHFQENHPKAKVVVLDKFRSNTLFSNNRPSSLGHFKNL 65 Query: 73 AGATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKT 132 G G ++ D+ P + D L + AA + + Sbjct: 66 IGFKGE---VIAADINNPLDLRRLEKL------HFDYLFHQAAVSDTTMLNQ------EL 110 Query: 133 VMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITA--TLGNRGQALQ--------VHAGSAK 182 VM + N+ + R ++ ++ GN G +K Sbjct: 111 VMKTNYQAFLNLLEIA-----RSKKAKVIYASSAGVYGNTKAPNVVGKNESPENVYGFSK 165 Query: 183 AAVDAMTRHLAVEWGPQNIR-VNSLAP 208 +D + + +R N P Sbjct: 166 LCMDEFVLSHSNDNVQVGLRYFNVYGP 192 >1OC2-A nrPDB Length = 348 Score = 45.3 bits (106), Expect = 3e-05, Method: Composition-based stats. Identities = 29/195 (14%), Positives = 51/195 (26%), Gaps = 29/195 (14%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVR 88 K +TGG IG + + L G R + D+ Sbjct: 5 KNIIVTGGAGFIGSNFVHYVYNNHPDVHVTVLDKLTYAGNKANLEAILGDRVELVVGDIA 64 Query: 89 APPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVL 148 V +A D +++ AA + S N + + GT+ + Sbjct: 65 DAELVDKLAAKA-------DAIVHYAAESH----NDNSLNDPSPFIHTNFIGTYTLLEAA 113 Query: 149 YEKFFR-------DHGGVIVNITATLGNRGQAL-----------QVHAGSAKAAVDAMTR 190 + R + G + G+ S KAA D + + Sbjct: 114 RKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETNYNPSSPYSSTKAASDLIVK 173 Query: 191 HLAVEWGPQNIRVNS 205 +G + N Sbjct: 174 AWVRSFGVKATISNC 188 >5B6K-A nrPDB Length = 366 Score = 45.3 bits (106), Expect = 3e-05, Method: Composition-based stats. Identities = 15/115 (13%), Positives = 36/115 (31%), Gaps = 14/115 (12%) Query: 14 LPAYRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLA 73 +P H+ F++G I + + + + RS + + + Sbjct: 15 VPRGSHMT--------TVFVSGATGFIAQHVVRQLLDQNYKVIGSVRSAEKG-DHLKNVI 65 Query: 74 GATGRRCLPLSMDVRAPPAVMAAVDQALKEFGR-IDILINCAAGNFLCPAGALSF 127 G + D+ P A D ++ G+ I ++++ A+ Sbjct: 66 FKGGDFNYEIVKDISDP----TAFDHVFEKHGKDIKVVLHTASPFHFNTTDIEKD 116 >1GY8-A nrPDB Length = 397 Score = 43.8 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 29/207 (14%), Positives = 53/207 (25%), Gaps = 49/207 (23%) Query: 31 AFITGGGSGIGFRIAEIFMRH-GCHTVIASR---------SLPRVLTAARKLAGATGRR- 79 + GG IG +R VI + ARKL + G + Sbjct: 5 VLVCGGAGYIGSHFVRALLRDTNHSVVIVDSLVGTHGKSDHVETRENVARKLQQSDGPKP 64 Query: 80 ------CLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTV 133 DVR ++ G ID +++ A + + + Sbjct: 65 PWADRYAALEVGDVRNED----FLNGVFTRHGPIDAVVHMCAFLAVGESVRDPLKYYDN- 119 Query: 134 MDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQ------------------ 175 + G + + I+ +++ G Sbjct: 120 ---NVVGILRLLQA----MLLHKCDKII-FSSSAAIFGNPTMGSVSTNAEPIDINAKKSP 171 Query: 176 -VHAGSAKAAVDAMTRHLAVEWGPQNI 201 G +K + M R A +G + I Sbjct: 172 ESPYGESKLIAERMIRDCAEAYGIKGI 198 >1BXK-A nrPDB Length = 355 Score = 42.6 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 24/182 (13%), Positives = 52/182 (28%), Gaps = 27/182 (14%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVR 88 + ITGG IG + + V+ L A R +D+ Sbjct: 2 RKILITGGAGFIGSALVRYIINETSDAVVVVDKLTYAGNLMSLAPVAQSERFAFEKVDIC 61 Query: 89 APPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNV---S 145 + + + D +++ AA + + + ++ + GT+ + + Sbjct: 62 DRAELARVFTEH-----QPDCVMHLAAESHVDRSIDGP----AAFIETNIVGTYTLLEAA 112 Query: 146 RVLYEKFFRDHGGVI----VNITATLG-----------NRGQALQVHAGSAKAAVDAMTR 190 R + D ++ G A ++KA+ D + R Sbjct: 113 RAYWNALTEDKKSAFRFHHISTDEVYGDLHSTDDFFTETTPYAPSSPYSASKASSDHLVR 172 Query: 191 HL 192 Sbjct: 173 AW 174 >3PVZ-A nrPDB Length = 399 Score = 42.6 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 29/224 (12%), Positives = 68/224 (30%), Gaps = 22/224 (9%) Query: 32 FITGGGSGIGFRIAEI-FMRHGCHTVIASRSLPRVLTAARKLAGATG---RRCLPLSMDV 87 + GG IG + + F R+ + S ++ R + + G ++D+ Sbjct: 39 LVLGGAGSIGQAVTKEIFKRNPQKLHVVDISENNMVELVRDIRSSFGYINGDFQTFALDI 98 Query: 88 RAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRV 147 + D +K G+ D ++N +A + ++D++ T + Sbjct: 99 GSIE-----YDAFIKADGQYDYVLNLSALKHVRSEKDPFT--LMRMIDVNVFNTDKTIQQ 151 Query: 148 LYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLA 207 + + + ++ G++K ++ + E R ++A Sbjct: 152 SIDAGAKKYF-------CVSTDKAANPVNMMGASKRIMEMFLMRKSEEIAISTARFANVA 204 Query: 208 PGPISGTEGLRRLGGPQASLSTKVTASPLQR-LGNKTEIAHSVL 250 S L V + ++R E L Sbjct: 205 ---FSDGSLLHGFNQRIQKNQPIVAPNDIKRYFVTPQESGELCL 245 >2Z95-A nrPDB Length = 345 Score = 41.8 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 25/124 (20%), Positives = 46/124 (37%), Gaps = 12/124 (9%) Query: 26 LRDKVAFITGGGSGI-GFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLS 84 + K A ITG G G +A++ + G A R + K G + Sbjct: 1 MSGKRALITGI-RGQDGAYLAKLLLEKGYEVYGADRRSGEFASWRLKELGIE-NDVKIIH 58 Query: 85 MDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNV 144 MD+ ++ +++ + D + N AA +F+ +SF ++D G + Sbjct: 59 MDLLEFSNIIRTIEKV-----QPDEVYNLAAQSFVG----VSFEQPILTAEVDAIGVLRI 109 Query: 145 SRVL 148 L Sbjct: 110 LEAL 113 >1GPJ-A nrPDB Length = 404 Score = 41.8 bits (97), Expect = 4e-04, Method: Composition-based stats. Identities = 22/112 (19%), Positives = 42/112 (37%), Gaps = 24/112 (21%) Query: 24 DLLRDKVAFITGGGSGIGFRIAEIFMRHGCH-TVIASRSLPRVLTAARKLAGATGRRCLP 82 L DK + G G +G +A+ + G ++A+R+ R + AR L G Sbjct: 163 GSLHDKTVLVVGAGE-MGKTVAKSLVDRGVRAVLVANRTYERAVELARDLGG-------- 213 Query: 83 LSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVM 134 AV D+ + R D++++ A P + + + + Sbjct: 214 --------EAVR--FDELVDHLARSDVVVSATA----APHPVIHVDDVREAL 251 >1ZZE-A nrPDB Length = 342 Score = 41.8 bits (97), Expect = 4e-04, Method: Composition-based stats. Identities = 24/148 (16%), Positives = 44/148 (29%), Gaps = 15/148 (10%) Query: 27 RDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMD 86 + +TG + + E + HG +RS ++ ++ R Sbjct: 10 EGSLVLVTGANGFVASHVVEQLLEHGYKVRGTARSASKLANLQKRWDAKYPGRFET---- 65 Query: 87 VRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSR 146 A V+ LK+ G D +I AAG + N + V+ GT N R Sbjct: 66 --------AVVEDMLKQ-GAYDEVIKGAAGVAHIASVVSFSNKYDEVVTPAIGGTLNALR 116 Query: 147 VLYEKFFRDHGGVIVNITATLGNRGQAL 174 ++ + + Sbjct: 117 AAAATPSVKRF--VLTSSTVSALIPKPN 142 >1R66-A nrPDB Length = 337 Score = 41.8 bits (97), Expect = 4e-04, Method: Composition-based stats. Identities = 41/265 (15%), Positives = 75/265 (28%), Gaps = 41/265 (15%) Query: 32 FITGGGSGIGFRIAEIFMRHG-----CHTVIASRSLPRVLTAARKLAGATGRRCLPLSMD 86 +TGG IG + VI SL A R + D Sbjct: 4 LVTGGAGFIGSHFVRQLLAGAYPDVPADEVIVLDSLTYAGNRANLAPVDADPRLRFVHGD 63 Query: 87 VRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSR 146 +R +E +D +++ AA + + S + + G ++ Sbjct: 64 IRDAG-------LLARELRGVDAIVHFAAESHVDR----SIAGASVFTETNVQG----TQ 108 Query: 147 VLYEKFFRDHGGVIVNIT-----------ATLGNRGQALQVHAGSAKAAVDAMTRHLAVE 195 L + G +V+++ + + ++KA D + R Sbjct: 109 TLLQCAVDAGVGRVVHVSTDEVYGSIDSGSWTESSPLEPNSPYAASKAGSDLVARAYHRT 168 Query: 196 WGPQ-NIR--VNSLAP--GPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTE-IAHSV 249 +G I N+ P P +L + ++ + + Sbjct: 169 YGLDVRITRCCNNYGPYQHPEKLIPLFVTNLLDGGTLPLYGDGANVREWVHTDDHCRGIA 228 Query: 250 LYLASPLASYVTGAVLVADGGAWLT 274 L LA A G + GG LT Sbjct: 229 LVLAGGRA----GEIYHIGGGLELT 249 >6ACF-A nrPDB Length = 367 Score = 41.5 bits (96), Expect = 4e-04, Method: Composition-based stats. Identities = 11/69 (15%), Positives = 22/69 (31%), Gaps = 3/69 (4%) Query: 21 FCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARK--LAGATGR 78 F D L KV + G G+ + + + G ++ + V A + Sbjct: 166 FGSDSLEGKVVAVQGVGN-VAYHLCRHLHEEGAKLIVTDINKEAVARAVEEFGAKAVDPN 224 Query: 79 RCLPLSMDV 87 + D+ Sbjct: 225 DIYGVECDI 233 >1VL0-A nrPDB Length = 292 Score = 41.5 bits (96), Expect = 5e-04, Method: Composition-based stats. Identities = 27/172 (15%), Positives = 45/172 (26%), Gaps = 47/172 (27%) Query: 32 FITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAPP 91 ITG +G I + G+ + DV+ Sbjct: 16 LITGANGQLGREIQKQL---------------------------KGKNVEVIPTDVQDLD 48 Query: 92 AVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVLYEK 151 + +++INCAA + + I+ G N++ Y Sbjct: 49 ITNVLAVNKFFNEKKPNVVINCAAHTAVDKCE----EQYDLAYKINAIGPKNLAAAAY-- 102 Query: 152 FFRDHGGVIVNITATLGNRGQAL-----------QVHAGSAKAAVDAMTRHL 192 G IV I+ G+A Q G K + + L Sbjct: 103 ---SVGAEIVQISTDYVFDGEAKEPITEFDEVNPQSAYGKTKLEGENFVKAL 151 >6GCS-E nrPDB Length = 375 Score = 41.1 bits (95), Expect = 7e-04, Method: Composition-based stats. Identities = 22/129 (17%), Positives = 40/129 (31%), Gaps = 18/129 (13%) Query: 27 RDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMD 86 A + G +G + +HG V+ R + K+ G G L MD Sbjct: 52 TGYTATVFGANGFLGSYLTAKLAKHGTTVVVPYR--EEMAKRHLKVTGDLGV-VNFLEMD 108 Query: 87 VRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSR 146 +R ++ AV + DI++N F D+ G ++ Sbjct: 109 LRNLESIDEAVRHS-------DIVVNLIG-------REYETKNFNY-YDVHVEGARRIAE 153 Query: 147 VLYEKFFRD 155 + + Sbjct: 154 AVKKHNIAR 162 >3HFS-A nrPDB Length = 338 Score = 40.7 bits (94), Expect = 8e-04, Method: Composition-based stats. Identities = 16/149 (10%), Positives = 39/149 (26%), Gaps = 15/149 (10%) Query: 20 LFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRR 79 + + K A + GG + + ++ ++ G R + L Sbjct: 1 MATQHPIGKKTACVVGGTGFVASLLVKLLLQKGYAVNTTVRDPDNQKKVSHLLELQELGD 60 Query: 80 CLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTS 139 D+ + A + D + + A P S + ++ Sbjct: 61 LKIFRADLTDELSFEAPIA-------GCDFVFHVA-----TPVHFASEDPENDMIKPAIQ 108 Query: 140 GTFNVSRVLYEKFFRDHGGVIVNITATLG 168 G NV + ++ ++ Sbjct: 109 GVVNVMKACTRA---KSVKRVILTSSAAA 134 >4PVC-A nrPDB Length = 342 Score = 40.3 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 16/141 (11%), Positives = 50/141 (35%), Gaps = 16/141 (11%) Query: 31 AFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAP 90 F++G I I ++ ++ + ++RS + + G + + + D+ Sbjct: 3 VFVSGANGFIAQHIVDLLLKEDYKVIGSARSQEKAENLT-EAFGNNPKFSMEVVPDISKL 61 Query: 91 PAVMAAVDQALKEFGR-IDILINCAAGNFLCPAGALSFNAFKTVM-DID-TSGTFNVSRV 147 A D ++ G+ I I+++ A+ ++ + ++ ++ G + + Sbjct: 62 D----AFDHVFQKHGKDIKIVLHTASPFCF----DITDSERDLLIPAVNGVKGILHSIKK 113 Query: 148 LYEKFFRDHGGVIVNITATLG 168 +V ++ Sbjct: 114 YAADSVE----RVVLTSSYAA 130 >1RKX-A nrPDB Length = 357 Score = 40.3 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 33/212 (15%), Positives = 64/212 (30%), Gaps = 36/212 (16%) Query: 20 LFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRR 79 + + K F+TG G ++ G S + P V + A G Sbjct: 1 MINNSFWQGKRVFVTGHTGFKGGWLSLWLQTMGATVKGYSLTAPTVPSLFETARVADG-- 58 Query: 80 CLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTS 139 + ++ ++ + + +I+ + AA P LS++ + Sbjct: 59 ---MQSEIGDIRDQNKLLESIREF--QPEIVFHMAA----QPLVRLSYSEPVETYSTNVM 109 Query: 140 GTFNVSRVLYEKFFRDHGGV--IVNITATLG------------NRGQALQVHAGSAKAAV 185 GT + R GGV +VNIT+ N ++K Sbjct: 110 GTVYLLEA-----IRHVGGVKAVVNITSDKCYDNKEWIWGYRENEAMGGYDPYSNSKGCA 164 Query: 186 DAMTRHLAVE------WGPQNIRVNSLAPGPI 211 + +T +G V ++ G + Sbjct: 165 ELVTSSYRNSFFNPANYGQHGTAVATVRAGNV 196 >1LU9-A nrPDB Length = 287 Score = 40.3 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 16/75 (21%), Positives = 24/75 (32%), Gaps = 2/75 (2%) Query: 24 DLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPL 83 ++ K A + G +G R A + G V+ R L + AA + Sbjct: 115 GSVKGKKAVVLAGTGPVGMRSAALLAGEGAEVVLCGRKLDKAQAAADSVNKRFKVNVTAA 174 Query: 84 SM--DVRAPPAVMAA 96 D AV A Sbjct: 175 ETADDASRAEAVKGA 189 >1KEU-A nrPDB Length = 361 Score = 39.9 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 27/200 (13%), Positives = 57/200 (28%), Gaps = 35/200 (17%) Query: 32 FITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAPP 91 ITGG IG + +++ TV+ L + R D+ Sbjct: 4 LITGGAGFIGSAVVRHIIKNTQDTVVNIDKLTYAGNLESLSDISESNRYNFEHADICDSA 63 Query: 92 AVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVLYE- 150 + +Q + D +++ AA + + + ++ + GT+ + V + Sbjct: 64 EITRIFEQY-----QPDAVMHLAAESHVDRSITGP----AAFIETNIVGTYALLEVARKY 114 Query: 151 --KFFRDHGGVI----VNITATLGNRGQAL-------------------QVHAGSAKAAV 185 D ++ G+ ++KA+ Sbjct: 115 WSALGEDKKNNFRFHHISTDEVYGDLPHPDEVENSVTLPLFTETTAYAPSSPYSASKASS 174 Query: 186 DAMTRHLAVEWGPQNIRVNS 205 D + R +G I N Sbjct: 175 DHLVRAWRRTYGLPTIVTNC 194 >2PZM-A nrPDB Length = 330 Score = 39.9 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 19/142 (13%), Positives = 42/142 (29%), Gaps = 26/142 (18%) Query: 14 LPAYRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLA 73 +P H+ ITGG +G + E ++ G ++ +A Sbjct: 15 VPRGSHM---------RILITGGAGCLGSNLIEHWLPQGHEILVIDNFATGKREVLPPVA 65 Query: 74 GATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTV 133 G + + V + A D +++ AA + + Sbjct: 66 GLS-----VIEGSVTDAGLLERAFDSFKPTH-----VVHSAAAYK-------DPDDWAED 108 Query: 134 MDIDTSGTFNVSRVLYEKFFRD 155 + G+ NV++ + + Sbjct: 109 AATNVQGSINVAKAASKAGVKR 130 >2NNL-D nrPDB Length = 337 Score = 39.9 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 30/254 (11%), Positives = 64/254 (25%), Gaps = 44/254 (17%) Query: 27 RDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPL-SM 85 + + +TG IG + + G R V L L L Sbjct: 4 QSETVCVTGASGFIGSWLVMRLLERGYTVRATVRDPTNVKKVKHLLDLPKAETHLTLWKA 63 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFK-TVMDIDTSGTFNV 144 D+ + A+ C + + V+ G + Sbjct: 64 DLADEGSFDEAIK-------------GCTGVFHVATPMDFESKDPENEVIKPTIEGMLGI 110 Query: 145 SRVLYEKFFRDHGGVIVNITATLGNRGQALQ-VHA----------GSAK---AAVDAMTR 190 + +V ++ Q Q AK A + +++ Sbjct: 111 MKSCAAAKTVR---RLVFTSSAGTVNIQEHQLPVYDESCWSDMEFCRAKKMTAWMYFVSK 167 Query: 191 HLAVEWG-----PQNIRVNSLAPGPISGTEGLRRLG-------GPQASLSTKVTASPLQR 238 LA + NI ++ P + G + + P + + Sbjct: 168 TLAEQAAWKYAKENNIDFITIIPTLVVGPFIMSSMPPSLITALSPITGNEAHYSIIRQGQ 227 Query: 239 LGNKTEIAHSVLYL 252 + ++ ++ +YL Sbjct: 228 FVHLDDLCNAHIYL 241 >4KTT-E nrPDB Length = 327 Score = 39.1 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 20/164 (12%), Positives = 49/164 (29%), Gaps = 38/164 (23%) Query: 17 YRHLFC--PDLLR-------DKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLT 67 H+ P+ + ++ +TG +G + + F ++ H V R Sbjct: 1 GSHMMPEMPEDMEQEEVNIPNRRVLVTGATGLLGRAVHKEFQQNNWHAVGCGFRRARPKF 60 Query: 68 AARKLAGATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSF 127 L + AV + +F + ++++CAA Sbjct: 61 EQVNLLDS-------------------NAVHHIIHDF-QPHVIVHCAAERRPDVVENQP- 99 Query: 128 NAFKTVMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRG 171 ++ + N+++ G ++ I++ G Sbjct: 100 ---DAASQLNVDASGNLAKEAAAV-----GAFLIYISSDYVFDG 135 >5K1S-A nrPDB Length = 362 Score = 39.1 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 19/80 (23%), Positives = 29/80 (36%), Gaps = 2/80 (2%) Query: 27 RDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGAT-GRRCLPLSM 85 + ITG G+G ++ G + + S +V A R L + Sbjct: 183 AGETVLITGASGGVGLSSVQLARLDGARVIAVTSSEAKVQALKEAGADEVIVSRGLDFAS 242 Query: 86 DVRAPPAVMAAVDQALKEFG 105 DVR A VD A++ G Sbjct: 243 DVRKRTQ-GAGVDVAVEIVG 261 >2C20-A nrPDB Length = 330 Score = 38.8 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 19/118 (16%), Positives = 31/118 (26%), Gaps = 7/118 (5%) Query: 32 FITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGR--RCLPLSMDVRA 89 I GG IG + + G V+ A + A R DV Sbjct: 5 LICGGAGYIGSHAVKKLVDEGLSVVVVDNLQTGHEDAITEGAKFYNGDLRDKAFLRDVFT 64 Query: 90 PPAVMAAVDQALKEFGRIDI-----LINCAAGNFLCPAGALSFNAFKTVMDIDTSGTF 142 + A + A + + N LC + + T+ T+ Sbjct: 65 QENIEAVMHFAADSLVGVSMEKPLQYYNNNVYGALCLLEVMDEFKVDKFIFSSTAATY 122 >3SC6-A nrPDB Length = 287 Score = 38.8 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 26/153 (16%), Positives = 45/153 (29%), Gaps = 29/153 (18%) Query: 54 HTVIASRSLPRVLTAARKLAGATGRRCLPLS---MDVRAPPAVMAAVDQALKEFGRIDIL 110 +I + +L P +D+ V V + R I+ Sbjct: 7 RVIITGANGQLGKQLQEEL-NPEEYDIYPFDKKLLDITNISQVQQVVQEI-----RPHII 60 Query: 111 INCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNR 170 I+CAA + A I+ G NV + + G +V I+ + Sbjct: 61 IHCAAYTKVDQAEK----ERDLAYVINAIGARNV--AVASQLV---GAKLVYISTDYVFQ 111 Query: 171 G-----------QALQVHAGSAKAAVDAMTRHL 192 G A G++K A + + L Sbjct: 112 GDRPEGYDEFHNPAPINIYGASKYAGEQFVKEL 144 >2EXX-A nrPDB Length = 306 Score = 38.4 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 14/81 (17%), Positives = 29/81 (35%), Gaps = 6/81 (7%) Query: 25 LLRDKVAFITGGGSGIGFRIAEIFMRHG-CHTVIASRSLPRVLTAARKLAGATGRRCLPL 83 ++ K+ + GG G +A + G + +R+ + +L GA + Sbjct: 8 MVDKKLVVVFGGTGAQGGSVARTLLEDGTFKVRVVTRNPRKKAAKELRLQGAE-----VV 62 Query: 84 SMDVRAPPAVMAAVDQALKEF 104 D + A++ A F Sbjct: 63 QGDQDDQVIMELALNGAYATF 83 >1ZDL-A nrPDB Length = 517 Score = 38.0 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 12/53 (22%), Positives = 20/53 (37%), Gaps = 4/53 (7%) Query: 14 LPAYRHLFCPDLLRDKVA---FITGGGSGIGFRIAEIFMRHGCHTVIASRSLP 63 +P H+ + + + GGGSG G A+ + G +A P Sbjct: 15 VPRGSHMASASAAGGQQSFDLLVIGGGSG-GLACAKEAAQLGKKVAVADYVEP 66 >1WVG-A nrPDB Length = 359 Score = 38.0 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 24/172 (13%), Positives = 54/172 (31%), Gaps = 32/172 (18%) Query: 27 RDKVAFITGGGSGIGFRIAEIFMRHGCHT---VIASRSLPRVLTAARKLAGATGRRCLPL 83 + K F+TG G ++ G + + ++P + R Sbjct: 8 QGKRVFVTGHTGFKGSWLSLWLTEMGAIVKGYALDAPTVPSLFEIVR-----LNDLMESH 62 Query: 84 SMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFN 143 D+R + +++ + + +I+ + AA P LS+ + GT + Sbjct: 63 IGDIRDFEKLRSSIAEF-----KPEIVFHMAA----QPLVRLSYEQPIKTYSTNVMGTVH 113 Query: 144 VSRVLYEKFFRDHGGVIVNITATLG------------NRGQALQVHAGSAKA 183 + + + + +VNIT+ N ++K Sbjct: 114 LLETVKQV---GNIKAVVNITSDKCYDNREWVWGYRENEPMGGYDPYSNSKG 162 >5INT-A nrPDB Length = 220 Score = 37.6 bits (86), Expect = 0.006, Method: Composition-based stats. Identities = 21/117 (17%), Positives = 39/117 (33%), Gaps = 35/117 (29%) Query: 23 PDLLRDKVAFITGG---------------GSG-IGFRIAEIFMRHGCHTVIASRSLPRVL 66 + L+ K IT G SG +G+ IAE+ + G ++ S Sbjct: 1 SNALQGKRILITAGPTREKIDPVRFMTNFSSGKMGYAIAEVAVNLGAEVILVS------- 53 Query: 67 TAARKLAGATGRRCLPLSMDVR--APPAVMAAVDQALKEFGRIDILINCAAGNFLCP 121 G L + V + ++ ++ + +D++I AA P Sbjct: 54 ----------GPTALNPPLHVTTVQVESAQDMLEAVIQHYQNVDVVIKTAAVADYRP 100 >5N2I-A nrPDB Length = 232 Score = 37.6 bits (86), Expect = 0.006, Method: Composition-based stats. Identities = 13/47 (27%), Positives = 18/47 (38%) Query: 33 ITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRR 79 + GG G +A F G ++ SRS R A +L R Sbjct: 24 VLGGTGDQGRGLARRFAMAGHEVILGSRSAERAQAVAAELGEGLPVR 70 >3OND-A nrPDB Length = 488 Score = 37.6 bits (86), Expect = 0.006, Method: Composition-based stats. Identities = 11/63 (17%), Positives = 21/63 (33%), Gaps = 1/63 (1%) Query: 25 LLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLS 84 ++ KVA + G G +G A + G ++ L A + + Sbjct: 262 MIAGKVAVVAGYGD-VGKGCAAALKQAGARVIVTEIDPICALQATMEGLQVLTLEDVVSE 320 Query: 85 MDV 87 D+ Sbjct: 321 ADI 323 >6ACQ-A nrPDB Length = 302 Score = 37.6 bits (86), Expect = 0.007, Method: Composition-based stats. Identities = 12/50 (24%), Positives = 17/50 (34%), Gaps = 9/50 (18%) Query: 14 LPAYRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLP 63 +P H+ KV I G +G IA+ F G V+ Sbjct: 15 VPRGSHM-------KKVCVI--GAGTMGSGIAQAFAAKGFEVVLRDIKDE 55 >4EUF-A nrPDB Length = 418 Score = 37.2 bits (85), Expect = 0.007, Method: Composition-based stats. Identities = 20/103 (19%), Positives = 29/103 (28%), Gaps = 13/103 (12%) Query: 29 KVAFITGGGSGIGFR--IAEIFMRHGCHTVIASRSLPRVLTAA-----------RKLAGA 75 K I G SG G I+ F HT+ S ++ A Sbjct: 61 KKVLIVGASSGFGLATRISVAFGGPEAHTIGVSYETGATDRRIGTAGWYNNIFFKEFAKK 120 Query: 76 TGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNF 118 G D + + EFG+ID+ + A Sbjct: 121 KGLVAKNFIEDAFSNETKDKVIKYIKDEFGKIDLFVYSLAAPR 163 >3VPX-A nrPDB Length = 364 Score = 37.2 bits (85), Expect = 0.009, Method: Composition-based stats. Identities = 13/75 (17%), Positives = 26/75 (34%), Gaps = 5/75 (6%) Query: 21 FCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRC 80 F D L K + G G+ + + + E G +I + A ++ A G Sbjct: 166 FGDDSLAGKTVAVQGVGN-VAYALCEYLHEEGAKLIITDIN----EEAVQRAVDAFGATA 220 Query: 81 LPLSMDVRAPPAVMA 95 + ++ + A Sbjct: 221 VGINEIYSQEADIFA 235 >4A10-A nrPDB Length = 447 Score = 36.8 bits (84), Expect = 0.012, Method: Composition-based stats. Identities = 24/143 (16%), Positives = 51/143 (35%), Gaps = 21/143 (14%) Query: 27 RDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMD 86 + + I G G+G A F+++G +A S + A R L G + + Sbjct: 220 QGDIVLIWGASGGLG-SYAIQFVKNGGGIPVAVVSSAQKEAAVRAL----GCDLVINRAE 274 Query: 87 VRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSR 146 + + + ++ ++ L+ + AG F+ + TF +S Sbjct: 275 LGITDDIADDPRRVVETGRKLAKLV-------VEKAGREPDIVFEHTGRV----TFGLSV 323 Query: 147 VLYEKFFRDHGGVIVNITATLGN 169 ++ GG +V ++ G Sbjct: 324 IVA-----RRGGTVVTCGSSSGY 341 >6DEB-A nrPDB Length = 285 Score = 36.4 bits (83), Expect = 0.013, Method: Composition-based stats. Identities = 9/46 (19%), Positives = 17/46 (36%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARK 71 L K A I G + +G +A + + G + + R+ Sbjct: 158 LEGKDAVIIGASNIVGRPMATMLLNAGATVSVCHIKTKDLSLYTRQ 203 >4PZE-A nrPDB Length = 284 Score = 36.4 bits (83), Expect = 0.015, Method: Composition-based stats. Identities = 32/191 (16%), Positives = 68/191 (35%), Gaps = 14/191 (7%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVR 88 + I G G+ +G IA+ G + V+ S V +A + R + Sbjct: 4 RTVGIVGAGT-MGNGIAQACAVVGLNVVMVDISDAAVQKGVATVASSLDRLIKKEKLTEA 62 Query: 89 APPAVMAAVD--QALKEFGRIDILINCAAGNFLCPAGALSFNA---FKTVMDIDTSGTFN 143 + +A + + + DI+I A N+ L + V+ + + + Sbjct: 63 DKASALARIKGSTSYDDLKATDIVIEAATENYDLKVKILKQIDGIVGENVIIASNTSSIS 122 Query: 144 VSRVLYEKFFRDH--GGVIVNITATLGNRGQA-LQVHAGSAKAAVDAMTRHLAVEWGPQN 200 ++++ D G N + + + AAV+A+++ + G Sbjct: 123 ITKLAAVTSRADRFIGMHFFNPVPVMALVELIRGLQTSDTTHAAVEALSK----QLGKYP 178 Query: 201 IRVNSLAPGPI 211 I V + +PG + Sbjct: 179 ITVKN-SPGFV 188 >3LK7-A nrPDB Length = 451 Score = 36.1 bits (82), Expect = 0.018, Method: Composition-based stats. Identities = 7/56 (12%), Positives = 14/56 (25%), Gaps = 1/56 (1%) Query: 20 LFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGA 75 + +K + G G A + + G + A+ L Sbjct: 1 MKTITTFENKKVLVLGLARS-GEAAARLLAKLGAIVTVNDGKPFDENPTAQSLLEE 55 >3NJ4-A nrPDB Length = 435 Score = 36.1 bits (82), Expect = 0.019, Method: Composition-based stats. Identities = 25/157 (15%), Positives = 49/157 (31%), Gaps = 25/157 (15%) Query: 25 LLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLS 84 ++ KVA + G G +G A+ G +I L AA + T Sbjct: 213 MIAGKVAVVAGYGD-VGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQE 271 Query: 85 MDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDI-----DTS 139 ++ + G IDI++ A + F +D+ + Sbjct: 272 GNI------------FVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAV 319 Query: 140 GTFNVSRVLYEKFFRDHG-------GVIVNITATLGN 169 N+ + ++ G +VN+ +G+ Sbjct: 320 EKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGH 356 >1O89-A nrPDB Length = 345 Score = 35.3 bits (80), Expect = 0.028, Method: Composition-based stats. Identities = 10/57 (17%), Positives = 16/57 (28%), Gaps = 7/57 (12%) Query: 17 YRHLFCPDLLRDKVA-------FITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVL 66 + + C L D +TG G+G + + G V S Sbjct: 150 FTAMLCVMALEDAGVRPQDGEIVVTGASGGVGSTAVALLHKLGYQVVAVSGRESTHE 206 >4KUG-A nrPDB Length = 290 Score = 35.3 bits (80), Expect = 0.032, Method: Composition-based stats. Identities = 14/103 (13%), Positives = 33/103 (32%), Gaps = 3/103 (2%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVR 88 K F+ G G+ +G I + F GC ++ V + + + + Sbjct: 2 KKVFVLGAGT-MGAGIVQAFAAKGCEVIVRDIKEEFVDRGIATITKSLSKLVAKEKITEA 60 Query: 89 APPAVMAAVD--QALKEFGRIDILINCAAGNFLCPAGALSFNA 129 +++ + +K D+++ A N + Sbjct: 61 DKEEILSRISGTTDMKLAADCDLVVEAAIENMKIKKEIFAELD 103 >5YWN-A nrPDB Length = 334 Score = 34.9 bits (79), Expect = 0.043, Method: Composition-based stats. Identities = 24/152 (15%), Positives = 48/152 (31%), Gaps = 11/152 (7%) Query: 31 AFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAP 90 F++G + +I + + G V + RS + L G S +V Sbjct: 5 VFVSGATGYLAQQIIALVLSKGYKVVGSVRSEEKGAN----LKKLYGDD---FSYEVVKV 57 Query: 91 PAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDID-TSGTFNVSRVLY 149 A D+ALK+ + I ++ A+ + I+ T + + Sbjct: 58 LEQKGAFDEALKKHPEVTIFLHTAS---PVTFEVEDTEKEILIPAINGTKYVLQSIKDVA 114 Query: 150 EKFFRDHGGVIVNITATLGNRGQALQVHAGSA 181 + R V + G V + ++ Sbjct: 115 PQITRVVYTSSVVAMSVPEELGSPDVVLSEAS 146 >3ZU2-A nrPDB Length = 422 Score = 34.9 bits (79), Expect = 0.044, Method: Composition-based stats. Identities = 22/131 (16%), Positives = 38/131 (29%), Gaps = 21/131 (16%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHT----VIASRSLPRVL---------TAARKLAGA 75 K + G +G G A I GC V R A K A Sbjct: 65 KRVLVIGASTGYGLA-ARITAAFGCGADTLGVFFERPGEEGKPGTSGWYNSAAFHKFAAQ 123 Query: 76 TGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVM- 134 G ++ D + +D ++ G++D +I A + F + + Sbjct: 124 KGLYAKSINGDAFSDEIKQLTIDAIKQDLGQVDQVIYSLASPRRTHPK--TGEVFNSALK 181 Query: 135 ----DIDTSGT 141 ++ G Sbjct: 182 PIGNAVNLRGL 192 >3WMX-A nrPDB Length = 358 Score = 34.5 bits (78), Expect = 0.048, Method: Composition-based stats. Identities = 30/214 (14%), Positives = 55/214 (25%), Gaps = 47/214 (21%) Query: 14 LPAYRHLFCPDLLRDK-VAFITGGGSGIGFRIAEIFMRH-GCHTVIASRSLPRVLTAARK 71 +P H+ K I G IG +A G VI S +P Sbjct: 15 VPRGSHME-----AGKPKILIVGANGQIGSELALALAERYGRTNVITSDVVPTGRHVHLT 69 Query: 72 LAGATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFK 131 ++ + ++ G + + AA + A+ Sbjct: 70 HE----------MLNATDRGE----LATVVERHGITQVYLLAAALS--ATGEKAPQWAW- 112 Query: 132 TVMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRG------------QALQVHAG 179 +++ + NV E + + ++ G Sbjct: 113 ---NLNMTSLLNV----LELARQTGLERVFWPSSIAAFGPTTPAGQTPQKTVMEPTTVYG 165 Query: 180 SAKAAVDAMTRHLAVEWGPQNIRVNSLA-PGPIS 212 +K A + R + V S+ PG IS Sbjct: 166 ISKQAGEGWCRWY---HANHGVDVRSVRYPGLIS 196 >1RPN-A nrPDB Length = 335 Score = 34.5 bits (78), Expect = 0.050, Method: Composition-based stats. Identities = 13/70 (18%), Positives = 24/70 (34%), Gaps = 3/70 (4%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTV-IASRSLPRVLTAARKLAGATGRRCLPLSMDV 87 + A +TG G +A++ + G + +R R+L D+ Sbjct: 15 RSALVTGITGQDGAYLAKLLLEKGYRVHGLVARRSSDTRWRLREL--GIEGDIQYEDGDM 72 Query: 88 RAPPAVMAAV 97 +V AV Sbjct: 73 ADACSVQRAV 82 >4WLE-A nrPDB Length = 340 Score = 34.5 bits (78), Expect = 0.057, Method: Composition-based stats. Identities = 15/143 (10%), Positives = 38/143 (26%), Gaps = 29/143 (20%) Query: 14 LPAYRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLA 73 +P H+ + KVA + G GIG ++ + + +L Sbjct: 15 VPRGSHMSAQN--NAKVA-VLGASGGIGQPLSLLL---------------KNSPLVSRLT 56 Query: 74 GATGRRCLPLSMDVRAPPAVMAAV-----DQALKEFGRIDILINCAAGNFLCPAGALSFN 128 ++ D+ A +Q D+++ A Sbjct: 57 LYDIAHTPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTR---- 112 Query: 129 AFKTVMDIDTSGTFNVSRVLYEK 151 + + + + ++ + Sbjct: 113 --DDLFNTNATIVATLTAACAQH 133 >2VN8-A nrPDB Length = 375 Score = 34.5 bits (78), Expect = 0.059, Method: Composition-based stats. Identities = 18/119 (15%), Positives = 33/119 (27%), Gaps = 15/119 (12%) Query: 27 RDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMD 86 K I G G+G ++ H RKL D Sbjct: 183 TGKRVLILGASGGVGTFAIQVMKAWDAHVTAVC--SQDASELVRKLGAD----------D 230 Query: 87 VRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 V + +V++ LK D +++ G+ A + + F ++ Sbjct: 231 VIDYKS--GSVEEQLKSLKPFDFILDNVGGSTETWAPDF-LKKWSGATYVTLVTPFLLN 286 >1DB3-A nrPDB Length = 372 Score = 34.1 bits (77), Expect = 0.064, Method: Composition-based stats. Identities = 21/124 (16%), Positives = 40/124 (32%), Gaps = 13/124 (10%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLP----RVLTAARKLAGATGRRCLPLS 84 KVA ITG G +AE + G R + + + Sbjct: 2 KVALITGVTGQDGSYLAEFLLEKGYEVHGIKRRASSFNTERVDHIYQDPHTCNPKFHLHY 61 Query: 85 MDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNV 144 D+ + + + + D + N A + + +SF + + D+D GT + Sbjct: 62 GDLSDTSNLTRILREV-----QPDEVYNLGAMSHVA----VSFESPEYTADVDAMGTLRL 112 Query: 145 SRVL 148 + Sbjct: 113 LEAI 116 >3N58-A nrPDB Length = 464 Score = 34.1 bits (77), Expect = 0.069, Method: Composition-based stats. Identities = 15/86 (17%), Positives = 26/86 (30%), Gaps = 13/86 (15%) Query: 25 LLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLS 84 ++ KVA + G G +G A+ G + V A G + L Sbjct: 244 MMAGKVAVVCGYGD-VGKGSAQSLAGAGARVKVT-----EVDPICALQAAMDGFEVVTL- 296 Query: 85 MDVRAPPAVMAAVDQALKEFGRIDIL 110 + D + G D++ Sbjct: 297 ------DDAASTADIVVTTTGNKDVI 316 >4K28-A nrPDB Length = 269 Score = 34.1 bits (77), Expect = 0.071, Method: Composition-based stats. Identities = 12/51 (23%), Positives = 16/51 (31%), Gaps = 2/51 (3%) Query: 27 RDKVAFITGGGSGIGFRIAEIFMRHG-CHTVIASRSLPRVLTAARKLAGAT 76 K A + G G G+G IA G + S R+ L Sbjct: 124 AGKRALVIGCG-GVGSAIAYALAEAGIASITLCDPSTARMGAVCELLGNGF 173 >5F5N-A nrPDB Length = 289 Score = 33.7 bits (76), Expect = 0.090, Method: Composition-based stats. Identities = 12/77 (15%), Positives = 22/77 (28%), Gaps = 5/77 (6%) Query: 28 DKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDV 87 ++ +TG G + G R A AG ++ D+ Sbjct: 1 NRTILVTGATGTQGGATVRALLARGRPVRALVRDPGTDAARALAAAG-----VSLVTGDL 55 Query: 88 RAPPAVMAAVDQALKEF 104 ++ AA+ F Sbjct: 56 NDQASLRAAMADVHGVF 72 >6G2J-P nrPDB Length = 377 Score = 33.7 bits (76), Expect = 0.10, Method: Composition-based stats. Identities = 18/104 (17%), Positives = 32/104 (30%), Gaps = 9/104 (8%) Query: 24 DLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPL 83 + VA + G +G + R G +I R +L G G+ L Sbjct: 49 SSVSGVVATVFGATGFLGRYVVNHLGRMGSQVIIPYR-CDVYDIMHLRLMGDLGQ-LTFL 106 Query: 84 SMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSF 127 D R ++ AV + +++IN + Sbjct: 107 EWDARDKDSIRKAVQHS-------NVVINLIGREWETRNFDFED 143 >2C54-A nrPDB Length = 379 Score = 33.4 bits (75), Expect = 0.13, Method: Composition-based stats. Identities = 19/123 (15%), Positives = 36/123 (29%), Gaps = 17/123 (13%) Query: 33 ITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAPPA 92 ITG G I IA G + + + +T + + Sbjct: 34 ITGAGGFIASHIARRLKHEGHYVIASDWKKNEHMTE-----DMFCDEFHLVDL------- 81 Query: 93 VMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVLYEKF 152 ++ LK +D + N AA + + +M +T +FN+ Sbjct: 82 --RVMENCLKVTEGVDHVFNLAADMGGMGFIQSNHSV---IMYNNTMISFNMIEAARING 136 Query: 153 FRD 155 + Sbjct: 137 IKR 139 >3DMF-A nrPDB Length = 381 Score = 33.4 bits (75), Expect = 0.13, Method: Composition-based stats. Identities = 25/100 (25%), Positives = 36/100 (36%), Gaps = 14/100 (14%) Query: 14 LPAYRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLA 73 L A + P+ +R + G G G + R G V L VL+ + L Sbjct: 220 LEALQERLGPEGVRGRQVLDLGAGYG---ALTLPLARMGAEVVGVEDDLASVLSLQKGL- 275 Query: 74 GATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINC 113 A + L DV D+AL E R DI++ Sbjct: 276 EANALKAQALHSDV----------DEALTEEARFDIIVTN 305 >5ENV-A nrPDB Length = 347 Score = 33.4 bits (75), Expect = 0.14, Method: Composition-based stats. Identities = 19/114 (16%), Positives = 39/114 (34%), Gaps = 12/114 (10%) Query: 14 LPAYRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRH-GCHTVIASRSLPRVLTAARKL 72 + Y+ L +L+ I+G G+G +A + + G + +L Sbjct: 156 ITVYKALKSANLMAGHWVAISGAAGGLG-SLAVQYAKAMGYRVLGID-----GGEGKEEL 209 Query: 73 AGATGRRCLPLSMDVRAPPAVMAAVDQALK--EFGRIDILINCAAGNFLCPAGA 124 + G +D ++ AV +A G I++ ++ AA Sbjct: 210 FRSIGGEVF---IDFTKEKDIVGAVLKATDGGAHGVINVSVSEAAIEASTRYVR 260 >1JAY-A nrPDB Length = 212 Score = 33.0 bits (74), Expect = 0.15, Method: Composition-based stats. Identities = 16/69 (23%), Positives = 25/69 (36%), Gaps = 1/69 (1%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVR 88 +VA + GG +G +A G V+ SR + A + G + + Sbjct: 2 RVALL-GGTGNLGKGLALRLATLGHEIVVGSRREEKAEAKAAEYRRIAGDASITGMKNED 60 Query: 89 APPAVMAAV 97 A A AV Sbjct: 61 AAEACDIAV 69 >4J6F-A nrPDB Length = 382 Score = 33.0 bits (74), Expect = 0.16, Method: Composition-based stats. Identities = 13/87 (14%), Positives = 26/87 (29%), Gaps = 16/87 (18%) Query: 17 YRHLFCPDLLR-DKVAFITGGGSGIGFRIAEIFMRHGCH-TVIASRSLPRVL-------- 66 + L + +TG G+G I ++ G +A + Sbjct: 195 GERMLERARLAAGETVLVTGASGGVGSAIIQLARARGAVPIAVAGPGKEAAMLDIGAQAV 254 Query: 67 ------TAARKLAGATGRRCLPLSMDV 87 A + A+G R + + D+ Sbjct: 255 VTRGQGDLAEAVEAASGGRPIDVVADL 281 >2X86-A nrPDB Length = 357 Score = 33.0 bits (74), Expect = 0.17, Method: Composition-based stats. Identities = 17/107 (15%), Positives = 38/107 (35%), Gaps = 20/107 (18%) Query: 18 RHLFCPDLLRD-------KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAAR 70 +H+ PDL ++ +TGG IG I + G ++ +L Sbjct: 29 QHMDSPDLGTGGGSGIEGRMIIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGT---- 84 Query: 71 KLAGATGRRCLPLSMDVRAPPAVMAAVDQAL--KEFGRIDILINCAA 115 + + +++ + Q + +EFG ++ + + A Sbjct: 85 -------KFVNLVDLNIADYMDKEDFLIQIMAGEEFGDVEAIFHEGA 124 >4FCU-A nrPDB Length = 253 Score = 33.0 bits (74), Expect = 0.17, Method: Composition-based stats. Identities = 19/96 (19%), Positives = 39/96 (40%), Gaps = 7/96 (7%) Query: 44 IAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAPPAVMAAVDQALKE 103 IAEI G V+ S P ++A G + ++V+ ++ A Q +++ Sbjct: 54 IAEICRAEGVDVVLTSADHPSGTDRLSEVARIKGWDADDIIVNVQGDEPLLPA--QLVQQ 111 Query: 104 FGRIDILI---NCAAGNFLCPAGALSFNAFKTVMDI 136 ++ L+ NC+ P AL +++ + Sbjct: 112 VAKL--LVDKPNCSMSTLCEPIHALDEFQRDSIVKV 145 >3RUE-A nrPDB Length = 351 Score = 33.0 bits (74), Expect = 0.18, Method: Composition-based stats. Identities = 30/206 (14%), Positives = 55/206 (26%), Gaps = 30/206 (14%) Query: 11 DDCLPAYRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRV----L 66 D + Y + + K ITG IG + VI + L Sbjct: 8 DIYMSRYEEITQQLIFSPKTWLITGVAGFIG-SNLLEKLLKLNQVVIGLDNFSTGHQYNL 66 Query: 67 TAARKLAGATG-RRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGAL 125 + L R + D+R + +D +++ AA + + Sbjct: 67 DEVKTLVSTEQWSRFCFIEGDIRDLTTCEQVMK-------GVDHVLHQAALGSVPRSIVD 119 Query: 126 SFNAFKTVMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLG----------NRGQALQ 175 T + +G N+ + ++T G N G L Sbjct: 120 PI----TTNATNITGFLNILHAAKNAQVQSFTYA--ASSSTYGDHPALPKVEENIGNPL- 172 Query: 176 VHAGSAKAAVDAMTRHLAVEWGPQNI 201 K + + A +G + I Sbjct: 173 SPYAVTKYVNEIYAQVYARTYGFKTI 198 >6C55-A nrPDB Length = 340 Score = 32.6 bits (73), Expect = 0.19, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 19/64 (29%), Gaps = 1/64 (1%) Query: 24 DLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPL 83 D L+ K + G GS G A+ +G VI R A Sbjct: 13 DALQGKKIAVVGYGS-QGHAHAQNLKDNGYDVVIGIRPGRSFDKAKEDGFDVFPVAEAVK 71 Query: 84 SMDV 87 DV Sbjct: 72 QADV 75 >5JXW-A nrPDB Length = 498 Score = 32.6 bits (73), Expect = 0.20, Method: Composition-based stats. Identities = 23/162 (14%), Positives = 46/162 (28%), Gaps = 23/162 (14%) Query: 22 CPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARK------LAGA 75 C +L K + G G +G A+ G ++ L A+ + L Sbjct: 265 CIQMLAGKKIVVLGYGE-VGKGCAQGLSGVGARVIVTEIDPICALQASMEGYQVSVLEDV 323 Query: 76 TGRRCLPLSM----DVRAPPAVMAAVDQA-LKEFGRIDILINCAAGNFLCPAGALSFNAF 130 + ++ DV + + A + G D I+ + Sbjct: 324 VSEADIFITATGNKDVITVEHMRKMKENAYIANIGHFDDEIDVYGLENYPGIKVIEVKQ- 382 Query: 131 KTVMDIDT-SGTFNVSRVLYEKFFRDHGGVIVNITATLGNRG 171 + TF ++ + G +VN+ G+ Sbjct: 383 ------NVHKFTFPDTQKSVILLCK---GRLVNLGCATGHPP 415 >4EJ0-A nrPDB Length = 342 Score = 32.6 bits (73), Expect = 0.20, Method: Composition-based stats. Identities = 21/158 (13%), Positives = 46/158 (29%), Gaps = 23/158 (14%) Query: 32 FITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAPP 91 +TG IG + + G +IA +L R + ++ Sbjct: 16 IVTGAAGFIGANLVKALNERGETRIIAVDNLTRADKFKN-----------LVDCEIDDYL 64 Query: 92 AVMAAVDQ-ALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDT---SGTFNVSRV 147 V++ A +FG++ + + A + + +MD + + Sbjct: 65 DKTEFVERFARGDFGKVRAVFHEGACSDTM------ETDGRYMMDNNFRYSRAVLDACLA 118 Query: 148 LYEKFFRDHGGVIVNITA--TLGNRGQALQVHAGSAKA 183 +F I ++ +A G +K Sbjct: 119 QGAQFLYASSAAIYGGSSRFVEEREVEAPLNVYGYSKF 156 >6GBN-A nrPDB Length = 438 Score = 32.6 bits (73), Expect = 0.22, Method: Composition-based stats. Identities = 17/95 (17%), Positives = 32/95 (33%), Gaps = 12/95 (12%) Query: 25 LLRDKVAFITGGGSGIGFRIAEIFMRHGCHTV------IASRSLPRVLTAARKLAGATGR 78 ++ KVA + G G +G A G + I + +K+A A R Sbjct: 216 MMAGKVAVVAGYGD-VGKGSAASLRGAGARVIVTEIDPICALQAAMDGYEVKKMADAVKR 274 Query: 79 RCLPLSM----DVRAPPAVMAAVDQ-ALKEFGRID 108 + ++ ++ A D+ + G D Sbjct: 275 ADIVVTATGNKNIITGEHFKAMRDKVIVCNIGHFD 309 >3DOJ-A nrPDB Length = 310 Score = 32.2 bits (72), Expect = 0.25, Method: Composition-based stats. Identities = 15/129 (11%), Positives = 36/129 (27%), Gaps = 22/129 (17%) Query: 14 LPAYRHLFCPDLLRDKVAFITGGGSGI-GFRIAEIFMRHGCHTVIASRSLPRVLTAARKL 72 +P H+ L G GI G ++ +++G + +R+L + Sbjct: 15 VPRGSHMMEVGFL----------GLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVE-- 62 Query: 73 AGATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGN----FLCPAGALSFN 128 G +V + + ++ + +S Sbjct: 63 ---HGASVCESPAEV--IKKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTV 117 Query: 129 AFKTVMDID 137 +T + I+ Sbjct: 118 DAETSLKIN 126 >2HK7-A nrPDB Length = 269 Score = 32.2 bits (72), Expect = 0.30, Method: Composition-based stats. Identities = 12/78 (15%), Positives = 28/78 (35%), Gaps = 11/78 (14%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 +++K + G G G + ++ G + +R+ + + A+K Sbjct: 121 VKEKSILVLGAG-GASRAVIYALVKEGAKVFLWNRTKEKAIKLAQKFPLEV--------- 170 Query: 86 DVRAPPAVMAAVDQALKE 103 V +P V+ V + Sbjct: 171 -VNSPEEVIDKVQVIVNT 187 >2GGS-A nrPDB Length = 273 Score = 31.8 bits (71), Expect = 0.33, Method: Composition-based stats. Identities = 18/116 (15%), Positives = 37/116 (31%), Gaps = 25/116 (21%) Query: 32 FITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAPP 91 ITG +G ++ + + S ++ G +D+ P Sbjct: 4 LITGASGQLGIELSRLLSERH-EVIKVYNSS--------EIQGGY-------KLDLTDFP 47 Query: 92 AVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRV 147 + D +K+ R D++IN AA + + I+ ++ R Sbjct: 48 RLE---DFIIKK--RPDVIINAAAMTDVDKCE----IEKEKAYKINAEAVRHIVRA 94 >1C0L-A nrPDB Length = 363 Score = 31.8 bits (71), Expect = 0.34, Method: Composition-based stats. Identities = 13/41 (31%), Positives = 17/41 (41%), Gaps = 1/41 (2%) Query: 27 RDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLT 67 K + G G IG A I R G I +R LP ++ Sbjct: 5 SQKRVVVLGSGV-IGLSSALILARKGYSVHILARDLPEDVS 44 >3H0K-A nrPDB Length = 178 Score = 31.8 bits (71), Expect = 0.35, Method: Composition-based stats. Identities = 19/100 (19%), Positives = 35/100 (35%), Gaps = 24/100 (24%) Query: 29 KVAFITGGGSGIGF-RIAEIFMRHGCHTV-----------IASRSLPRVLTAARKLAGAT 76 KV ITG G G A++ G + I ++ R++ A++L Sbjct: 1 KVILITG-MPGSGKSEFAKLLKERGAKVIVMSDVVRKRYSIEAKPGERLMDFAKRLREIY 59 Query: 77 GRRCLPLSM---------DVRAPPAVMAAVDQALKEFGRI 107 G + D+ V + + ++EF R+ Sbjct: 60 GDGVVARLCVEELGTSNHDLVVFDGVRSLAE--VEEFKRL 97 >3CT4-A nrPDB Length = 332 Score = 31.8 bits (71), Expect = 0.36, Method: Composition-based stats. Identities = 20/113 (17%), Positives = 37/113 (32%), Gaps = 13/113 (11%) Query: 14 LPAYRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHG---CHT---VIASRSLPRVLT 67 +P + + KVA ++GGGSG A F+ G + S + ++ Sbjct: 32 VPDFEIIQRKSPKSGKVALVSGGGSGHEPAHA-GFVGEGMLSAAVCGAIFTSPTPDQIYE 90 Query: 68 AARKLAGATGRRCLP--LSMDVRAPPAVMAAVDQALKEFGRI----DILINCA 114 A + G + DV + + +I DI + + Sbjct: 91 AIKSADEGAGVLLIIKNYLGDVMNFEMAREMAEMEEIKVEQIIVDDDIAVENS 143 >2ZJ8-A nrPDB Length = 720 Score = 31.4 bits (70), Expect = 0.41, Method: Composition-based stats. Identities = 19/103 (18%), Positives = 30/103 (29%), Gaps = 7/103 (6%) Query: 15 PAYRHLFCPDLLRDKVAFI---TGGGSGIGFRIA---EIFMRHGCHTVIAS-RSLPRVLT 67 P +L K A I T G + IA I + G I ++L Sbjct: 26 PPQAEALKSGILEGKNALISIPTASGKTLIAEIAMVHRILTQGGKAVYIVPLKALAEEKF 85 Query: 68 AARKLAGATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDIL 110 + G R + D + + D + + D L Sbjct: 86 QEFQDWEKIGLRVAMATGDYDSKDEWLGKYDIIIATAEKFDSL 128 >4WOK-A nrPDB Length = 336 Score = 31.4 bits (70), Expect = 0.42, Method: Composition-based stats. Identities = 29/221 (13%), Positives = 62/221 (28%), Gaps = 34/221 (15%) Query: 31 AFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAP 90 + GG IG A++ G V+ +A R + D+ Sbjct: 14 VLVVGGAGFIGSHTAKLLAGQGYAPVVYDNLSTGHQSAVRW--------GDFVEGDILDQ 65 Query: 91 PAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVLYE 150 ++ +++ +I+ AA ++ S + GT ++ Sbjct: 66 ARLVETMEKYAPV-----AVIHFAASAYVG----ESVEDPAKYYRNNVGGTQSLLDACRL 116 Query: 151 KFFRDHGGVIVNITATLGNRGQALQ------------VHAGSAKAAVDAMTRHLAVEWGP 198 ++ V +++ G + G K + M AV +G Sbjct: 117 TRTQN-----VIFSSSCATYGVPSRLPIGEGEAQNPINPYGRTKLIAEHMLADYAVAYGL 171 Query: 199 QNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRL 239 + + + L P+ L + + RL Sbjct: 172 RYVALRYFNASGADIDGELGEKHDPETHLIPRAMMAAAGRL 212 >3X2F-A nrPDB Length = 411 Score = 31.4 bits (70), Expect = 0.43, Method: Composition-based stats. Identities = 27/162 (16%), Positives = 49/162 (30%), Gaps = 24/162 (14%) Query: 20 LFCPDLL-RDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARK------L 72 + +LL K + G G G IA G ++ + + A + Sbjct: 188 MRNTNLLVAGKNVVVAGYGW-CGRGIALRAAGLGARVIVTEVDPVKAVEAIMDGFTVMPM 246 Query: 73 AGATGRRCLPLSM----DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFN 128 A ++ DV + +++ D A +L N N P L Sbjct: 247 KEAVKIADFVITASGNTDVLSKEDILSLKDGA--------VLANAGHFNVEIPVRVLEEI 298 Query: 129 AFKTVMDI-DTSGTFNVSRVLYEKFFRDHGGVIVNITATLGN 169 A + + +G + G +VN+ A G+ Sbjct: 299 AVEKFEARPNVTGYTLENGKTVFLLAE---GRLVNLAAGDGH 337 Score = 31.4 bits (70), Expect = 0.44, Method: Composition-based stats. Identities = 20/163 (12%), Positives = 45/163 (27%), Gaps = 13/163 (7%) Query: 44 IAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAPPAVMAAVDQALKE 103 +A + G VI + + + G + + L E Sbjct: 50 LAITLSKLGAKVVITGSNPLSTQDDVAEALRSKGITVYARRTH--DESIYRENLMKVLDE 107 Query: 104 FGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVL---YEKFFRDHGGVI 160 R D +I+ +S + V++ + G + + + Sbjct: 108 --RPDFIIDDGGD-----LTVISHTEREEVLE-NLKGVSEETTTGVRRLKALEETGKLRV 159 Query: 161 VNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRV 203 I G+ ++ DA+ R+ + +N+ V Sbjct: 160 PVIAVNDSKMKYLFDNRYGTGQSTWDAIMRNTNLLVAGKNVVV 202 >5GUP-L nrPDB Length = 377 Score = 31.4 bits (70), Expect = 0.43, Method: Composition-based stats. Identities = 13/111 (11%), Positives = 31/111 (27%), Gaps = 14/111 (12%) Query: 24 DLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPL 83 + VA + G +G + R G ++ R P R + + + + Sbjct: 49 SSVSGIVATVFGATGFLGRYVVNHLGRMGSQVIVPYRCEPYDTMHLRPMGDL--GQIIFM 106 Query: 84 SMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVM 134 + + ++ V+ + N + F+ V Sbjct: 107 EWNGKDKDSIRKVVEH------------SNVVINLVGREWETKNFDFEDVF 145 >2DFV-A nrPDB Length = 347 Score = 31.4 bits (70), Expect = 0.45, Method: Composition-based stats. Identities = 16/82 (19%), Positives = 27/82 (32%), Gaps = 10/82 (12%) Query: 24 DLLRDKVAFITGGG--SGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGAT----- 76 + K ITG G +G +A+ G + VI S A+K+ Sbjct: 163 GPISGKSVLITGAGPLGLLGIAVAK---ASGAYPVIVSEPSDFRRELAKKVGADYVINPF 219 Query: 77 GRRCLPLSMDVRAPPAVMAAVD 98 + MD+ V ++ Sbjct: 220 EEDVVKEVMDITDGNGVDVFLE 241 >5UOG-A nrPDB Length = 344 Score = 31.4 bits (70), Expect = 0.51, Method: Composition-based stats. Identities = 22/108 (20%), Positives = 34/108 (31%), Gaps = 3/108 (2%) Query: 21 FCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAAR--KLAGATGR 78 P LR + + G G IG IA G +R+ L L G Sbjct: 157 LSPLSLRGRTVGLFGLGR-IGLAIARRLEAFGVSIAYHTRTPREGLGFTYHPTLVGMAEA 215 Query: 79 RCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALS 126 + + + A L G +LIN G+ + A ++ Sbjct: 216 VDTLIVIVPGTASTLKAVNADVLSALGPKGVLINVGRGSTVDEAALVT 263 >4B4V-A nrPDB Length = 303 Score = 31.4 bits (70), Expect = 0.52, Method: Composition-based stats. Identities = 12/55 (21%), Positives = 26/55 (47%), Gaps = 3/55 (5%) Query: 27 RDKVAFITGGGSGIGFRIAEIFMRHGCHTVIA---SRSLPRVLTAARKLAGATGR 78 K A + G + +G +A + ++ I +++LP ++ A + GA G+ Sbjct: 178 AGKHAVVVGRSAILGKPMAMMLLQANATVTICHSRTQNLPELVKQADIIVGAVGK 232 >5EGS-A nrPDB Length = 376 Score = 31.4 bits (70), Expect = 0.53, Method: Composition-based stats. Identities = 20/79 (25%), Positives = 28/79 (35%), Gaps = 9/79 (11%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATG--RRCLPL 83 LR K G G+GI ++ + G V A + AR++ G R L Sbjct: 82 LRGKTVLDVGAGTGI---LSIFCAQAGARRVYA-VEASAIWQQAREVVRFNGLEDRVHVL 137 Query: 84 SMDVRA---PPAVMAAVDQ 99 V P V A V + Sbjct: 138 PGPVETVELPEQVDAIVSE 156 >1U3W-A nrPDB Length = 374 Score = 31.4 bits (70), Expect = 0.53, Method: Composition-based stats. Identities = 16/91 (17%), Positives = 29/91 (31%), Gaps = 9/91 (9%) Query: 29 KVAFITGGG-------SGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCL 81 KVA +T G G+G + G +IA A++L Sbjct: 185 KVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQ 244 Query: 82 PLSMDVRA--PPAVMAAVDQALKEFGRIDIL 110 ++ VD + + G++D + Sbjct: 245 DYKKPIQEVLKEMTDGGVDFSFEVIGQLDTM 275 >5M65-A nrPDB Length = 479 Score = 31.1 bits (69), Expect = 0.53, Method: Composition-based stats. Identities = 14/63 (22%), Positives = 23/63 (36%), Gaps = 1/63 (1%) Query: 25 LLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLS 84 +L KVA + G G +G A + GC +++ L AA + Sbjct: 257 MLSGKVAMVAGFGD-VGKGSAASLRQAGCRVMVSEVDPICALQAAMEGYEVVTMEDAAPR 315 Query: 85 MDV 87 D+ Sbjct: 316 ADI 318 >4BKP-A nrPDB Length = 336 Score = 31.1 bits (69), Expect = 0.54, Method: Composition-based stats. Identities = 15/130 (11%), Positives = 34/130 (26%), Gaps = 29/130 (22%) Query: 18 RHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATG 77 +L+ + +TGG +G I + + G L G Sbjct: 16 ENLYFQSM----RILVTGGSGLVGKAI-QKVVADGAG-----------------LPGEDW 53 Query: 78 RRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDID 137 D+ A ++ ++ A L + + ++ + ++ Sbjct: 54 VFVSSKDADLTDTAQTRALFEKVQPTH----VIHLAAMVGGLFRNIKYNLDFWRKNVHMN 109 Query: 138 ---TSGTFNV 144 F V Sbjct: 110 DNVLHSAFEV 119 >5UZH-A nrPDB Length = 345 Score = 31.1 bits (69), Expect = 0.55, Method: Composition-based stats. Identities = 20/116 (17%), Positives = 37/116 (31%), Gaps = 15/116 (12%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLP----RVLTAARKLAGATGRRCLPLS 84 KVA ITG G +AE + G R + K T + L Sbjct: 2 KVALITGITGQDGSYLAEFLLEKGYMVYGIIRRSSSFNTGRVEHLYKDIHITKAKFKLLY 61 Query: 85 MDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSG 140 D+ +++ + + + D + N AA + + + + + G Sbjct: 62 GDLTDTGNLISIIAKI-----KPDEIYNLAAQSHVKVSFEMPE------YTANVDG 106 >2Q1T-A nrPDB Length = 377 Score = 31.1 bits (69), Expect = 0.56, Method: Composition-based stats. Identities = 11/90 (12%), Positives = 26/90 (28%), Gaps = 9/90 (10%) Query: 14 LPAYRHL---FCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCH-TVIASRSLPRVLTAA 69 +P H+ L + + GG +G + + + G + + L A Sbjct: 15 VPRGSHMPVIMNASKLANTNVMVVGGAGFVGSNLVKRLLELGVNQVHVVDNLLS-----A 69 Query: 70 RKLAGATGRRCLPLSMDVRAPPAVMAAVDQ 99 K+ + + + D+ Sbjct: 70 EKINVPDHPAVRFSETSITDDALLASLQDE 99 >4CQD-A nrPDB Length = 423 Score = 31.1 bits (69), Expect = 0.62, Method: Composition-based stats. Identities = 18/119 (15%), Positives = 44/119 (36%), Gaps = 10/119 (8%) Query: 56 VIASRSLPRVLTAARKLAGATGRRCLPLS-----MDVRAPPAVMAAVDQALKEFGRIDIL 110 V ++++ VL A +L + + + +D+ + + ++D G +D Sbjct: 151 VAKTKAVEAVLEAKEELKDLIDIQVVAFAQSGFFVDLESESLIRKSLDMGCDLVGGVDPA 210 Query: 111 I--NCAAGNFL---CPAGALSFNAFKTVMDIDTSGTFNVSRVLYEKFFRDHGGVIVNIT 164 N G+ A + + DI T G ++++R+ + + G + Sbjct: 211 TRENNVEGSLDLCFKLAKEYDVDIDYHIHDIGTVGVYSINRLAQKTIENGYKGRVTTSA 269 >4EJ6-A nrPDB Length = 370 Score = 31.1 bits (69), Expect = 0.66, Method: Composition-based stats. Identities = 26/113 (23%), Positives = 36/113 (31%), Gaps = 11/113 (9%) Query: 8 VEGDDCLPAYRHLFC---PDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPR 64 V G C P L + I GGG IG ++ G TVI S Sbjct: 160 VHGAFCEPLACCLHGVDLSGIKAGSTVAILGGGV-IGLLTVQLARLAGATTVILSTRQAT 218 Query: 65 VLTAARKLAGATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGN 117 A ++ ++D A V A G +D++I CA Sbjct: 219 KRRLAEEVGA-------TATVDPSAGDVVEAIAGPVGLVPGGVDVVIECAGVA 264 >3D64-A nrPDB Length = 494 Score = 31.1 bits (69), Expect = 0.66, Method: Composition-based stats. Identities = 11/63 (17%), Positives = 20/63 (31%), Gaps = 1/63 (1%) Query: 25 LLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLS 84 ++ K+A + G G +G A+ G + L AA + Sbjct: 274 MIAGKIAVVAGYGD-VGKGCAQSLRGLGATVWVTEIDPICALQAAMEGYRVVTMEYAADK 332 Query: 85 MDV 87 D+ Sbjct: 333 ADI 335 >1ZCJ-A nrPDB Length = 463 Score = 31.1 bits (69), Expect = 0.67, Method: Composition-based stats. Identities = 12/72 (16%), Positives = 25/72 (34%) Query: 40 IGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAPPAVMAAVDQ 99 +G IA F R G V ++ A + + + + +A Sbjct: 48 MGRGIAISFARVGISVVAVESDPKQLDAAKKIITFTLEKEASRAHQNGQASAKPKLRFSS 107 Query: 100 ALKEFGRIDILI 111 + KE +D+++ Sbjct: 108 STKELSTVDLVV 119 >4GBJ-A nrPDB Length = 297 Score = 30.7 bits (68), Expect = 0.70, Method: Composition-based stats. Identities = 16/115 (13%), Positives = 43/115 (37%), Gaps = 9/115 (7%) Query: 23 PDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLP 82 + + +K+AF+ G +G IAEI + G V+ +R+ + + A Sbjct: 1 SNAMSEKIAFL--GLGNLGTPIAEILLEAGYELVVWNRTASKAEPLTKLGATVVENAIDA 58 Query: 83 LS------MDVRAPPAVMAAVD-QALKEFGRIDILINCAAGNFLCPAGALSFNAF 130 ++ + AV + +++ G+ + ++ + + + + Sbjct: 59 ITPGGIVFSVLADDAAVEELFSMELVEKLGKDGVHVSMSTISPETSRQLAQVHEW 113 >3HZZ-A nrPDB Length = 467 Score = 30.7 bits (68), Expect = 0.73, Method: Composition-based stats. Identities = 19/150 (12%), Positives = 30/150 (20%), Gaps = 33/150 (22%) Query: 27 RDKVAFITGGGSGIGFRIAEIFMRHGCH----TVIASRSLPRVLTAARKLAGATGRRCLP 82 + I G G+G A F G V + + + + Sbjct: 246 QGDNVLIWGASGGLG-SYATQFALAGGANPICVVSSPQKAEICRSMGAEAIIDRNAEGYK 304 Query: 83 LSMD--VRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSG 140 D + P + + G DI F Sbjct: 305 FWKDEHTQDPKEWKRFGKRIRELTGGEDI---------DIVFEHPGRETFGA-------S 348 Query: 141 TFNVSRVLYEKFFRDHGGVIVNITATLGNR 170 + GG I +T G Sbjct: 349 VYVT----------RKGGTITTCASTSGYM 368 >3RI6-A nrPDB Length = 430 Score = 30.7 bits (68), Expect = 0.75, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 23/67 (34%), Gaps = 3/67 (4%) Query: 36 GGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAPPAVMA 95 G + I I R G V R L+ +K + G + DV AV Sbjct: 106 GMAAISTAI-LTLARAGDSVVTTDRLFGHTLSLFQKTLPSFGIEVRFV--DVMDSLAVEH 162 Query: 96 AVDQALK 102 A D+ K Sbjct: 163 ACDETTK 169 >2EER-A nrPDB Length = 347 Score = 30.7 bits (68), Expect = 0.75, Method: Composition-based stats. Identities = 9/44 (20%), Positives = 13/44 (29%), Gaps = 1/44 (2%) Query: 29 KVAFITGGGSGIG-FRIAEIFMRHGCHTVIASRSLPRVLTAARK 71 K + G G G+G I G + + A R Sbjct: 172 KTLVVIGAGGGLGTMAIQIAKAVSGATIIGVDVREEALEAAKRA 215 >3H9U-A nrPDB Length = 436 Score = 30.7 bits (68), Expect = 0.81, Method: Composition-based stats. Identities = 26/167 (15%), Positives = 48/167 (28%), Gaps = 25/167 (14%) Query: 25 LLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLS 84 ++ K A + G G +G A G V+ L AA + G + L + Sbjct: 208 MIAGKTACVCGYGD-VGKGCAAALRGFGARVVVTEVDPINALQAAME-----GYQVLLVE 261 Query: 85 MDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDI-----DTS 139 DV + + G DI+ + A + F T + + + Sbjct: 262 -DVVEEAHIF------VTTTGNDDIITSEHFPRMRDDAIVCNIGHFDTEIQVAWLKANAK 314 Query: 140 GTFNVSRVLYEKFFRDHG-------GVIVNITATLGNRGQALQVHAG 179 V + + G +VN+ G+ + Sbjct: 315 ERVEVKPQVDRYTMANGRHIILLAEGRLVNLGCASGHPSFVMSNSFC 361 >1N7G-A nrPDB Length = 381 Score = 30.7 bits (68), Expect = 0.81, Method: Composition-based stats. Identities = 29/199 (14%), Positives = 51/199 (25%), Gaps = 28/199 (14%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRC-----LPL 83 K+A ITG G + E + G R T Sbjct: 29 KIALITGITGQDGSYLTEFLLGKGYEVHGLIRRSSNFNTQRINHIYIDPHNVNKALMKLH 88 Query: 84 SMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFN 143 D+ ++ +D + D + N AA + + +SF D+ +G Sbjct: 89 YADLTDASSLRRWIDVI-----KPDEVYNLAAQSHVA----VSFEIPDYTADVVATGALR 139 Query: 144 VSRVLYEKFFRD-------HGGVIVNITAT----LGNRGQALQVHAGSAKAAVDAMT--- 189 + + G +T + ++K A T Sbjct: 140 LLEAVRSHTIDSGRTVKYYQAGSSEMFGSTPPPQSETTPFHPRSPYAASKCAAHWYTVNY 199 Query: 190 RHLAVEWGPQNIRVNSLAP 208 R + I N +P Sbjct: 200 REAYGLFACNGILFNHESP 218 >5LV5-A nrPDB Length = 403 Score = 30.7 bits (68), Expect = 0.87, Method: Composition-based stats. Identities = 19/81 (23%), Positives = 28/81 (34%), Gaps = 7/81 (8%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATG--RRCLPL 83 LR K G G+GI ++ + G V A + AR++ G R L Sbjct: 109 LRGKTVLDVGAGTGI---LSIFCAQAGARRVYA-VEASAIWQQAREVVRLNGLEDRVHVL 164 Query: 84 SMDVRAPPAVMAAVDQALKEF 104 V VD + E+ Sbjct: 165 PGPVETVELPER-VDAIVSEW 184 >3R9I-A nrPDB Length = 260 Score = 30.7 bits (68), Expect = 0.87, Method: Composition-based stats. Identities = 9/36 (25%), Positives = 15/36 (41%), Gaps = 5/36 (13%) Query: 29 KVAFITGGGSGIGF-----RIAEIFMRHGCHTVIAS 59 ++ +T G G+G IA + G TV+ Sbjct: 3 RIIVVTSGKGGVGKTTSSAAIATGLAQKGKKTVVID 38 >3ZWA-A nrPDB Length = 742 Score = 30.7 bits (68), Expect = 0.87, Method: Composition-based stats. Identities = 12/72 (16%), Positives = 25/72 (34%) Query: 40 IGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAPPAVMAAVDQ 99 +G IA F R G V ++ A + + + + +A Sbjct: 327 MGRGIAISFARVGISVVAVESDPKQLDAAKKIITFTLEKEASRAHQNGQASAKPKLRFSS 386 Query: 100 ALKEFGRIDILI 111 + KE +D+++ Sbjct: 387 STKELSTVDLVV 398 >2OWO-A nrPDB Length = 671 Score = 30.3 bits (67), Expect = 0.91, Method: Composition-based stats. Identities = 14/75 (18%), Positives = 26/75 (34%), Gaps = 2/75 (2%) Query: 24 DLLRDKVAFITGGGSGIGFRIAE-IFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLP 82 K +TG S + A+ + G S S L A + AG+ + Sbjct: 596 SPFAGKTVVLTGSLSQMSRDDAKARLVELGAKVA-GSVSKKTDLVIAGEAAGSKLAKAQE 654 Query: 83 LSMDVRAPPAVMAAV 97 L ++V ++ + Sbjct: 655 LGIEVIDEAEMLRLL 669 >5TC4-A nrPDB Length = 316 Score = 30.3 bits (67), Expect = 1.00, Method: Composition-based stats. Identities = 17/114 (14%), Positives = 29/114 (25%), Gaps = 16/114 (14%) Query: 28 DKVAFITGGGSGIGFRIAEIFMRHGCH--------TVIASRSLPRVLTAARKLAGATGRR 79 K + G +G IA + G H I+ R P+ + Sbjct: 159 GKNVVVAGRSKNVGMPIAMLLHTDGAHERPGGDATVTISHRYTPKEQLKKHTILADIVIS 218 Query: 80 CLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTV 133 + + D + ID+ IN + F+ V Sbjct: 219 AAGIPNLIT--------ADMIKEGAAVIDVGINRVHDPVTAKPKLVGDVDFEGV 264 >3BIC-A nrPDB Length = 762 Score = 30.3 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 18/94 (19%), Positives = 25/94 (26%), Gaps = 8/94 (8%) Query: 44 IAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAPPAVMAAVDQALKE 103 IA F G I + R++A + V + +KE Sbjct: 624 IATGFADLGFDVDIGP-----LFQTPREVAQQAVDADVHAVGVSTLAAGHKTLVPELIKE 678 Query: 104 F---GRIDILINCAAGNFLCPAGALSFNAFKTVM 134 GR DIL+ C L V Sbjct: 679 LNSLGRPDILVMCGGVIPPQDYEFLFEVGVSNVF 712 >4QQR-A nrPDB Length = 301 Score = 30.3 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 19/134 (14%), Positives = 39/134 (29%), Gaps = 19/134 (14%) Query: 71 KLAGATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAF 130 KL A G S ++ +++A ++ + AAG P + Sbjct: 30 KLCEAQGITYTYGSGRLQDRQSIVADIESVKPSH------VFNAAGVTGRPNVDWCESHK 83 Query: 131 KTVMDIDTSGTFNVSRVLYEK---FFRDHGGVIVNITATLGN----------RGQALQVH 177 + + +GT ++ + EK G I + Sbjct: 84 VETIRTNVAGTLTLADICREKGLVLINYATGCIFEYDSGHPLGSGIGFKEEDTPNFTGSF 143 Query: 178 AGSAKAAVDAMTRH 191 KA V+ + ++ Sbjct: 144 YSKTKAMVEELLKN 157 >1VPD-A nrPDB Length = 299 Score = 29.9 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 29/67 (43%), Gaps = 5/67 (7%) Query: 23 PDLLRDKVAFITGGGSGI-GFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAG-ATGRRC 80 + + KV FI G GI G +++ ++ G V++ R+ + A A+ + Sbjct: 1 SNAMTMKVGFI---GLGIMGKPMSKNLLKAGYSLVVSDRNPEAIADVIAAGAETASTAKA 57 Query: 81 LPLSMDV 87 + DV Sbjct: 58 IAEQCDV 64 >4UUP-A nrPDB Length = 341 Score = 29.9 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 18/101 (17%), Positives = 26/101 (25%), Gaps = 15/101 (14%) Query: 31 AFITGGGSGIGFRIAEIFMRHGC----HTVIASRSLPRVLTAARKLAGATGRRCLPLSMD 86 ITG IG+ +A + V+ +P + A + P Sbjct: 7 VLITGAAGQIGYALAFRIAKGDLFGDRKVVLHLLEIPPAMKALEGVCMELQDCAFPTLAG 66 Query: 87 VRAPPAVMAAVDQALKEF-----------GRIDILINCAAG 116 V A A F R D+L A Sbjct: 67 VVATDDPEEAFKDVDVAFLVGSFPRKPGMERADLLEKNAGI 107 >4BM5-A nrPDB Length = 348 Score = 29.9 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 29/70 (41%), Gaps = 3/70 (4%) Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 DV P V A E G I I ++ +F G L + V ++ G F+++ Sbjct: 7 DVGDDPFVRRAGAFLGIEAGTITIELSNL-IDFYIRNGILEMENEQAVYPVNLRGVFDLN 65 Query: 146 RVLYEKFFRD 155 + ++ +R Sbjct: 66 --ILQEMYRQ 73 >6HRD-A nrPDB Length = 317 Score = 29.9 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 15/83 (18%), Positives = 29/83 (34%), Gaps = 7/83 (8%) Query: 14 LPAYRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLA 73 +P H+ D ++ +V + G G +G IAE+ R G + + + ++ Sbjct: 15 VPRGSHM--SDAIQ-RVGVV-GAGQ-MGSGIAEVSARAGVEVTVFEPAEALITAGRNRIV 69 Query: 74 GATGRRCLPLSMDVRAPPAVMAA 96 + R V A Sbjct: 70 KSLERAVSAGK--VTERERDRAL 90 >4GGP-A nrPDB Length = 401 Score = 29.9 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 14/100 (14%), Positives = 32/100 (32%), Gaps = 14/100 (14%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAAR-------------KLAGA 75 K + G +G G + I G S + + + + A Sbjct: 51 KNVLVLGCSNGYGLA-SRITAAFGYGAATIGVSFEKAGSETKYGTPGWYNNLAFDEAAKR 109 Query: 76 TGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAA 115 G + + D + +++A K+ + D+++ A Sbjct: 110 EGLYSVTIDGDAFSDEIKAQVIEEAKKKGIKFDLIVYSLA 149 >3PEF-A nrPDB Length = 287 Score = 29.9 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 12/47 (25%), Positives = 19/47 (40%), Gaps = 1/47 (2%) Query: 39 GI-GFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLS 84 GI G +A+ ++ GC I +RS + A A C + Sbjct: 10 GIMGSAMAKNLVKAGCSVTIWNRSPEKAEELAALGAERAATPCEVVE 56 >6C6P-A nrPDB Length = 458 Score = 29.5 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 13/72 (18%), Positives = 21/72 (29%), Gaps = 4/72 (5%) Query: 31 AFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAP 90 I G G +G +A + R G + R L + G + D+ Sbjct: 10 VIIVGAGV-LGSALAAVLSRDGRKVTVIERDLKEPDRIVGEFLQPGG---YHVLKDLGLG 65 Query: 91 PAVMAAVDQALK 102 V Q + Sbjct: 66 DTVEGLDAQVVN 77 >4V62-AB nrPDB Length = 510 Score = 29.5 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 24/67 (35%), Gaps = 7/67 (10%) Query: 184 AVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQ-----R 238 + + +A EWGP N PG + + G A L + P + R Sbjct: 173 GLTGSVQPVAPEWGPDG--FNPYNPGGVVAHHIAAGIVGIIAGLFHILVRPPQRLYKALR 230 Query: 239 LGNKTEI 245 +GN + Sbjct: 231 MGNIETV 237 >6BII-A nrPDB Length = 333 Score = 29.5 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 15/57 (26%), Positives = 22/57 (38%), Gaps = 3/57 (5%) Query: 20 LFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGAT 76 +F + K I G G IG IA+ G + +RS R A ++L Sbjct: 142 MFLGYDVYGKTIGIVGFGR-IGQAIAKRAKGFGMRILYTARS--RKPEAEKELGAEF 195 >5NUE-A nrPDB Length = 332 Score = 29.5 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 23/136 (16%), Positives = 38/136 (27%), Gaps = 19/136 (13%) Query: 31 AFITGGGSGIGFRIAEIFMR---HGCH--TVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 +TG IG+ + + R G ++ +P A + PL Sbjct: 8 VLVTGAAGQIGYALVPMIARGIMLGADQPVILHMLDIPPAAEALNGVKMELIDAAFPL-- 65 Query: 86 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVS 145 V+A D G +N A + K VM + + Sbjct: 66 ----LKGVVATTDAVEGCTG-----VNVA--VMVGGFPRKEGMERKDVMSKNV-SIYKSQ 113 Query: 146 RVLYEKFFRDHGGVIV 161 EK + V+V Sbjct: 114 AAALEKHAAPNCKVLV 129 >1IZL-B nrPDB Length = 472 Score = 29.5 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 24/67 (35%), Gaps = 7/67 (10%) Query: 184 AVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQ-----R 238 + + +A EWGP N PG + + G A L + P + R Sbjct: 173 GLTGSVQPVAPEWGPDG--FNPYNPGGVVAHHIAAGIVGIIAGLFHILVRPPQRLYKALR 230 Query: 239 LGNKTEI 245 +GN + Sbjct: 231 MGNIETV 237 >5HC7-A nrPDB Length = 261 Score = 29.5 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 18/79 (22%), Positives = 26/79 (32%), Gaps = 6/79 (7%) Query: 45 AEIF--MRHGCH--TVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAPPAVMAAVDQA 100 AE G H +A ++ AARK+A L D + Sbjct: 124 AEGLSQANKGMHFILAVAYGGREDIVEAARKIAAKVEHGI--LRPDDIDEATFEQHLMTN 181 Query: 101 LKEFGRIDILINCAAGNFL 119 + +F D+LI A L Sbjct: 182 ITKFPSPDLLIRAAGEQRL 200 >2IIR-A nrPDB Length = 403 Score = 29.5 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 15/79 (18%), Positives = 26/79 (32%) Query: 26 LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 + + G IG + + R G + R LP A + + L + Sbjct: 20 MEGEKVLCKGIAERIGIEGSRLVHRVGDEKHVIERELPDHEEALKLILNTLVDEKLGVIK 79 Query: 86 DVRAPPAVMAAVDQALKEF 104 D++ AV V + F Sbjct: 80 DLKEIDAVGHRVVHGGERF 98 >1E3J-A nrPDB Length = 352 Score = 29.5 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 18/97 (18%), Positives = 33/97 (34%), Gaps = 9/97 (9%) Query: 28 DKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDV 87 + G G IG +G V +RS PR L A+ + L +D Sbjct: 169 GTTVLVIGAGP-IGLVSVLAAKAYGAFVVCTARS-PRRLEVAKNCGAD-----VTLVVDP 221 Query: 88 RAPPAVMAAVDQALKEFGRI-DILINCAAGNFLCPAG 123 + +++ G + ++ I+C+ G Sbjct: 222 AKEEE-SSIIERIRSAIGDLPNVTIDCSGNEKCITIG 257 >5GXF-A nrPDB Length = 330 Score = 29.5 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 6/36 (16%), Positives = 9/36 (25%) Query: 31 AFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVL 66 +TG G+G I G + Sbjct: 153 VLVTGAAGGVGSVATAILAHLGYEVAAVTGRPETAD 188 >1Y0Y-A nrPDB Length = 353 Score = 29.5 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 10/78 (12%), Positives = 21/78 (26%), Gaps = 6/78 (7%) Query: 16 AYRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGA 75 +H F D++A T I +A+ + V + + Sbjct: 171 LGKHRFVSIAFDDRIAVYT-----I-LEVAKQLKDAKADVYFVATVQEEVGLRGARTSAF 224 Query: 76 TGRRCLPLSMDVRAPPAV 93 ++DV + Sbjct: 225 GIEPDYGFAIDVTIAADI 242 >3UMF-A nrPDB Length = 217 Score = 29.1 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 12/29 (41%), Positives = 16/29 (55%), Gaps = 1/29 (3%) Query: 14 LPAYRHLFCPDLLRDKVAFITGG-GSGIG 41 +P H+ L + KV F+ GG GSG G Sbjct: 15 VPRGSHMTDQKLAKAKVIFVLGGPGSGKG 43 >3S8M-A nrPDB Length = 422 Score = 29.1 bits (64), Expect = 2.2, Method: Composition-based stats. Identities = 18/100 (18%), Positives = 28/100 (28%), Gaps = 13/100 (13%) Query: 29 KVAFITGGGSGIGFR----IAEIFMRHGCHTVIASRSLPRVL--------TAARKLAGAT 76 K + G SG G A F A K A A Sbjct: 62 KKVLVIGASSGYGLASRITAAFGFGADTLGVFFEKPGTASKAGTAGWYNSAAFDKHAKAA 121 Query: 77 GRRCLPLSMDVRAPPAVMAAVDQALKEFGR-IDILINCAA 115 G ++ D + A ++ E G +D+++ A Sbjct: 122 GLYSKSINGDAFSDAARAQVIELIKTEMGGQVDLVVYSLA 161 >4B4O-A nrPDB Length = 298 Score = 29.1 bits (64), Expect = 2.3, Method: Composition-based stats. Identities = 21/132 (15%), Positives = 37/132 (28%), Gaps = 27/132 (20%) Query: 31 AFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAP 90 + GG IG + ++ G + SR +LA + C Sbjct: 3 VLVGGGTGFIGTALTQLLNARGHEVTLVSRKPGPGRITWDELAASGLPSC---------- 52 Query: 91 PAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVLYE 150 D +N A N L P + K V+ T +++ + + Sbjct: 53 -----------------DAAVNLAGENILNPLRRWNETFQKEVLGSRLETTQLLAKAITK 95 Query: 151 KFFRDHGGVIVN 162 V+V Sbjct: 96 APQPPKAWVLVT 107 >1HSZ-A nrPDB Length = 374 Score = 29.1 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 16/90 (17%), Positives = 27/90 (30%), Gaps = 9/90 (10%) Query: 30 VAFITGGG-------SGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLP 82 VA +T G G+G G +IA A++L Sbjct: 186 VAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 245 Query: 83 LSMDVRA--PPAVMAAVDQALKEFGRIDIL 110 ++ VD + + GR+D + Sbjct: 246 YKKPIQEVLKEMTDGGVDFSFEVIGRLDTM 275 >2ZJ1-A nrPDB Length = 495 Score = 29.1 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 20/104 (19%), Positives = 31/104 (29%), Gaps = 12/104 (11%) Query: 28 DKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARK------LAGATGRRCL 81 K I G G +G AE G + L A + + A G + Sbjct: 275 GKKVLICGYGD-VGKGCAEAMKGQGARVSVTEIDPINALQAMMEGFDVVTVEEAIGDADI 333 Query: 82 PLSM----DVRAPPAVMAAVDQAL-KEFGRIDILINCAAGNFLC 120 ++ D+ + A D A+ G D I+ A Sbjct: 334 VVTATGNKDIIMLEHIKAMKDHAILGNIGHFDNEIDMAGLERSG 377 >1YXY-A nrPDB Length = 234 Score = 29.1 bits (64), Expect = 2.6, Method: Composition-based stats. Identities = 11/57 (19%), Positives = 20/57 (35%), Gaps = 7/57 (12%) Query: 150 EKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSL 206 + + GG+IV+ + + + + A E G IR NS+ Sbjct: 9 KLMEQLKGGIIVSC------QALPGEPLYSET-GGIMPLMAKAAQEAGAVGIRANSV 58 >6CL4-A nrPDB Length = 313 Score = 29.1 bits (64), Expect = 2.6, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 29/81 (35%), Gaps = 17/81 (20%) Query: 14 LPAYRHLFCPDLLRDKVAFITG--GGSGIG------FRIAEIFMRHGCHTVIASRSL--- 62 +P H+ L+ + + G G IG + I E + G IA+ S Sbjct: 15 VPRGSHM-SASSLKFPIVLVHGLLGFDKIGGIYPYFYGIKEALEKAGAKVYIATLSALNS 73 Query: 63 -----PRVLTAARKLAGATGR 78 ++L RK+ TG Sbjct: 74 NELRGEQLLEFVRKVQAETGA 94 >3FBG-A nrPDB Length = 346 Score = 29.1 bits (64), Expect = 2.6, Method: Composition-based stats. Identities = 11/49 (22%), Positives = 17/49 (34%), Gaps = 1/49 (2%) Query: 27 RDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGA 75 K I G G+G IA + VI + S + +K+ Sbjct: 150 EGKTLLIINGAGGVG-SIATQIAKAYGLRVITTASRNETIEWTKKMGAD 197 >3VR3-A nrPDB Length = 600 Score = 28.7 bits (63), Expect = 2.7, Method: Composition-based stats. Identities = 16/67 (23%), Positives = 27/67 (40%), Gaps = 4/67 (5%) Query: 41 GFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAPPAVMAAVDQA 100 G IAE F G I + S R A R+++G + D P + + + + Sbjct: 317 GITIAEYFRDMGYDVAIMADSTSRWAEALREMSGRLEE----MPGDEGYPAYLGSRLAEY 372 Query: 101 LKEFGRI 107 + GR+ Sbjct: 373 YERSGRV 379 >5KIA-A nrPDB Length = 351 Score = 28.7 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 27/108 (25%), Positives = 36/108 (33%), Gaps = 9/108 (8%) Query: 5 PPDVEGD-----DCLPAYRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRH-GCH-TVI 57 PP++ D D H L + ITG G IG +A +H G VI Sbjct: 144 PPEISDDLAAIFDPFGNATHTALSFNLVGEDVLITGAGP-IGV-MAVAIAKHVGARNVVI 201 Query: 58 ASRSLPRVLTAARKLAGATGRRCLPLSMDVRAPPAVMAAVDQALKEFG 105 + R+ A R A DV A + D L+ G Sbjct: 202 TDINDYRLDLARRMGATRAVNVSRESLRDVMADLHMTEGFDVGLEMSG 249 >1NHQ-A nrPDB Length = 447 Score = 28.7 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 11/67 (16%), Positives = 19/67 (28%), Gaps = 3/67 (4%) Query: 30 VAFITGGGSGIGFRIAEIFMRHGCHTVIASR-SLPRVLTAARKLAGATGRRCLPLSMDVR 88 V I G IG AE F + G + P + ++ ++ + Sbjct: 152 VVVI--GSGYIGIEAAEAFAKAGKKVTVIDILDRPLGVYLDKEFTDVLTEEMEANNITIA 209 Query: 89 APPAVMA 95 V Sbjct: 210 TGETVER 216 >2BC1-A nrPDB Length = 490 Score = 28.7 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 11/32 (34%), Positives = 15/32 (46%), Gaps = 2/32 (6%) Query: 28 DKVAFITGGGSGIGFRIAEIFMRHGCHTVIAS 59 +VA + G IG +AE F R G V+ Sbjct: 195 KRVAVV--GAGYIGVELAEAFQRKGKEVVLID 224 >1F3L-A nrPDB Length = 321 Score = 28.7 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 18/87 (20%), Positives = 30/87 (34%), Gaps = 6/87 (6%) Query: 20 LFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLA--GATG 77 P + +DKV G G+GI A + G VIA +L A + Sbjct: 38 YQNPHIFKDKVVLDVGCGTGILSMFA---AKAGAKKVIA-VDQSEILYQAMDIIRLNKLE 93 Query: 78 RRCLPLSMDVRAPPAVMAAVDQALKEF 104 + + + + VD + E+ Sbjct: 94 DTIVLIKGKIEEVSLPVEKVDVIISEW 120 >2WWR-A nrPDB Length = 330 Score = 28.7 bits (63), Expect = 3.0, Method: Composition-based stats. Identities = 17/66 (25%), Positives = 19/66 (28%), Gaps = 1/66 (1%) Query: 21 FCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRC 80 C L I G G IG IA G + + PR AA A Sbjct: 148 LCGYGLTQSTVGIIGLGR-IGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPE 206 Query: 81 LPLSMD 86 L D Sbjct: 207 LAAQSD 212 >4E0B-A nrPDB Length = 313 Score = 28.7 bits (63), Expect = 3.0, Method: Composition-based stats. Identities = 9/20 (45%), Positives = 11/20 (55%), Gaps = 1/20 (5%) Query: 29 KVAFITGGGSGIGFRIAEIF 48 KVA I G GIG +A + Sbjct: 5 KVAVI-GAAGGIGQALALLL 23 >2X3N-A nrPDB Length = 399 Score = 28.7 bits (63), Expect = 3.2, Method: Composition-based stats. Identities = 12/52 (23%), Positives = 18/52 (34%), Gaps = 3/52 (5%) Query: 31 AFITGGGSGIGFRI-AEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCL 81 I G GIG + A + R G V+ ++ L G R + Sbjct: 9 VLINGC--GIGGAMLAYLLGRQGHRVVVVEQARRERAINGADLLKPAGIRVV 58 >1YB5-A nrPDB Length = 351 Score = 28.7 bits (63), Expect = 3.3, Method: Composition-based stats. Identities = 16/131 (12%), Positives = 44/131 (33%), Gaps = 20/131 (15%) Query: 27 RDKVAFITGGGSGIGFR---IAEIFM---------RHGCHTVIASRSLP----RVLTAAR 70 + + G G+G IA + G V+ + + R + Sbjct: 170 AGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIVLQNGAHEVFNHREVNYID 229 Query: 71 KLAGATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAF 130 K+ G + + + +++ V + D +L G I++ + P ++ + Sbjct: 230 KIKKYVGEKGIDIIIEM--LANVNLSKDLSLLSHGGRVIVVGSRGTIEINPRDTMAKES- 286 Query: 131 KTVMDIDTSGT 141 +++ + + Sbjct: 287 -SIIGVTLFSS 296 >6BMQ-A nrPDB Length = 523 Score = 28.4 bits (62), Expect = 3.5, Method: Composition-based stats. Identities = 9/26 (34%), Positives = 12/26 (46%) Query: 50 RHGCHTVIASRSLPRVLTAARKLAGA 75 G VIA+R+ R L A + G Sbjct: 385 EKGAKVVIANRTYERALELAEAIGGK 410 >2RIR-A nrPDB Length = 300 Score = 28.4 bits (62), Expect = 3.6, Method: Composition-based stats. Identities = 7/30 (23%), Positives = 11/30 (36%) Query: 41 GFRIAEIFMRHGCHTVIASRSLPRVLTAAR 70 G IA F G + + +RS + Sbjct: 169 GMTIARTFAALGANVKVGARSSAHLARITE 198 >1G6Q-1 nrPDB Length = 328 Score = 28.4 bits (62), Expect = 4.0, Method: Composition-based stats. Identities = 16/56 (28%), Positives = 25/56 (44%), Gaps = 4/56 (7%) Query: 22 CPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATG 77 DL +DK+ G G+GI A +HG VI + ++ A++L G Sbjct: 33 NKDLFKDKIVLDVGCGTGILSMFA---AKHGAKHVI-GVDMSSIIEMAKELVELNG 84 >1X9I-A nrPDB Length = 302 Score = 28.4 bits (62), Expect = 4.1, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 29/81 (35%), Gaps = 14/81 (17%) Query: 30 VAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRA 89 VA TGG + G TVI ++ + L A +DV+ Sbjct: 110 VAITTGG----------RLAQMGVPTVIVPKASAPRAALPQLLTAALHVVAKVYGIDVKI 159 Query: 90 PPAV----MAAVDQALKEFGR 106 P + A + + ++EF + Sbjct: 160 PEGLEPPNEALIHKLVEEFQK 180 >7REQ-A nrPDB Length = 727 Score = 28.4 bits (62), Expect = 4.2, Method: Composition-based stats. Identities = 19/98 (19%), Positives = 32/98 (32%), Gaps = 5/98 (5%) Query: 44 IAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAPPAVMAAVDQALKE 103 IA + G + L + + A + +S ++ A+ + L + Sbjct: 616 IATAYADLGFDVDVG--PLFQTPEETARQAVEADVHVVGVSSLAGGHLTLVPALRKELDK 673 Query: 104 FGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGT 141 GR DILI P ++I T GT Sbjct: 674 LGRPDILITVGGV---IPEQDFDELRKDGAVEIYTPGT 708 >3HDH-A nrPDB Length = 302 Score = 28.4 bits (62), Expect = 4.4, Method: Composition-based stats. Identities = 8/49 (16%), Positives = 21/49 (42%), Gaps = 1/49 (2%) Query: 33 ITGGGSGI-GFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRC 80 +T G G+ G IA++ G V+ ++ + + + + + + Sbjct: 18 VTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVA 66 >4W5U-B nrPDB Length = 408 Score = 28.0 bits (61), Expect = 4.5, Method: Composition-based stats. Identities = 15/82 (18%), Positives = 22/82 (26%), Gaps = 11/82 (13%) Query: 79 RCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFN---------A 129 L+ D P A + FG D L+ A P G + Sbjct: 186 NACGLTCDSSGPDAFRNLMAALRSTFG--DELVTAAVTADGTPGGKIEATDYAGAAQYVD 243 Query: 130 FKTVMDIDTSGTFNVSRVLYEK 151 + VM D G ++ Sbjct: 244 WYNVMTYDFFGAWDAQGPTAPH 265 >4A5O-A nrPDB Length = 286 Score = 28.0 bits (61), Expect = 4.7, Method: Composition-based stats. Identities = 7/41 (17%), Positives = 15/41 (36%) Query: 31 AFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARK 71 A + G + +G +A + GC + R + + Sbjct: 164 AVVVGASNIVGRPMALELLLGGCTVTVTHRFTRDLADHVSR 204 >1VRD-A nrPDB Length = 494 Score = 28.0 bits (61), Expect = 4.7, Method: Composition-based stats. Identities = 11/70 (15%), Positives = 23/70 (32%), Gaps = 1/70 (1%) Query: 42 FRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAPPAVMAAVDQAL 101 +A+ R G +I P + T + + V V A+D Sbjct: 63 AALAKALAREGGIGIIHKNLTPDEQARQVSIVKKTENGIIYDPITVTPDMTVKEAIDLMA 122 Query: 102 K-EFGRIDIL 110 + + G + ++ Sbjct: 123 EYKIGGLPVV 132 >3K6J-A nrPDB Length = 460 Score = 28.0 bits (61), Expect = 4.8, Method: Composition-based stats. Identities = 12/41 (29%), Positives = 16/41 (39%), Gaps = 2/41 (4%) Query: 30 VAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAAR 70 VA I GG +G +A F G T + R+ R Sbjct: 57 VAIIGGGT--MGKAMAICFGLAGIETFLVVRNEQRCKQELE 95 >1F14-A nrPDB Length = 310 Score = 28.0 bits (61), Expect = 4.8, Method: Composition-based stats. Identities = 8/49 (16%), Positives = 21/49 (42%), Gaps = 1/49 (2%) Query: 33 ITGGGSGI-GFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRC 80 +T G G+ G IA++ G V+ ++ + + + + + + Sbjct: 18 VTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVA 66 >3FFS-A nrPDB Length = 400 Score = 28.0 bits (61), Expect = 4.9, Method: Composition-based stats. Identities = 12/83 (14%), Positives = 26/83 (31%), Gaps = 6/83 (7%) Query: 21 FCPDLLRDKVAFITGGGSGIG---FRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATG 77 + + L +K G IG A++ + G ++ + L R L Sbjct: 124 YSNENLDNKGRLRVGAA--IGVNEIERAKLLVEAGVDVIVLDSAHGHSLNIIRTLKEIKS 181 Query: 78 R-RCLPLSMDVRAPPAVMAAVDQ 99 + + +V A ++ Sbjct: 182 KMNIDVIVGNVVTEEATKELIEN 204 >4AP9-A nrPDB Length = 201 Score = 28.0 bits (61), Expect = 5.0, Method: Composition-based stats. Identities = 8/35 (22%), Positives = 12/35 (34%) Query: 42 FRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGAT 76 + E G V+ S S VL ++L Sbjct: 85 RELVETLREKGFKVVLISGSFEEVLEPFKELGDEF 119 >4C5A-A nrPDB Length = 330 Score = 28.0 bits (61), Expect = 5.8, Method: Composition-based stats. Identities = 9/27 (33%), Positives = 15/27 (55%) Query: 12 DCLPAYRHLFCPDLLRDKVAFITGGGS 38 D +P +L+ + DK+A + GG S Sbjct: 11 DYIPTTENLYFNGAMTDKIAVLLGGTS 37 >4D3S-A nrPDB Length = 293 Score = 27.6 bits (60), Expect = 5.9, Method: Composition-based stats. Identities = 7/46 (15%), Positives = 15/46 (32%) Query: 40 IGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM 85 +G +A + G + +R+ + A + A L Sbjct: 19 MGQAMAGALLEAGYELTVWNRTKAKAEALAERGAAVADSPAEALRA 64 >2WEK-A nrPDB Length = 341 Score = 27.6 bits (60), Expect = 5.9, Method: Composition-based stats. Identities = 8/41 (19%), Positives = 12/41 (29%), Gaps = 2/41 (4%) Query: 27 RDKVAFITGGGSGIGFRIAEIFM-RHGCHTVIASRSLPRVL 66 K +T G G A + CH + S + Sbjct: 142 EGKKVLVTAAAGGTGQ-FAMQLSKKAKCHVIGTCSSDEKSA 181 >1IM2-A nrPDB Length = 444 Score = 27.6 bits (60), Expect = 5.9, Method: Composition-based stats. Identities = 9/58 (15%), Positives = 22/58 (37%), Gaps = 5/58 (8%) Query: 213 GTEGLRRLGGPQASLSTKVTASPLQRLGNKTE-IAHSVLYLASPLASYVTGAVLVADG 269 T+ ++++ ++ K +RL E + + + AS + G + D Sbjct: 370 TTDAVKKIAEAAFRVNEKTENIGARRLHTVMERLMDKISFSASD----MNGQTVNIDA 423 >4NPH-A nrPDB Length = 351 Score = 27.6 bits (60), Expect = 6.0, Method: Composition-based stats. Identities = 15/38 (39%), Positives = 21/38 (55%) Query: 44 IAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCL 81 IAE F +G V+ + SL R AAR++A A G + Sbjct: 148 IAEFFRDNGKRVVLLADSLTRYARAAREIALAAGETAV 185 >3T69-A nrPDB Length = 330 Score = 27.6 bits (60), Expect = 6.8, Method: Composition-based stats. Identities = 11/61 (18%), Positives = 16/61 (26%) Query: 40 IGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAPPAVMAAVDQ 99 IG IA G + + T R + G + D + AA Sbjct: 245 IGLEIAGALAGSGSVDGVCLVGSGGLGTLYRTALESQGLNVRAVDADEAVRAGLSAAARA 304 Query: 100 A 100 Sbjct: 305 I 305 >5ZVQ-A nrPDB Length = 194 Score = 27.6 bits (60), Expect = 7.1, Method: Composition-based stats. Identities = 27/179 (15%), Positives = 48/179 (26%), Gaps = 48/179 (26%) Query: 39 GIGFRIAEIFMRHGCHTVIASRSLP---------RVLTAARKLAGATGRRCLPLSMDVRA 89 GIG + A+ H + + A R+ P+ D Sbjct: 19 GIGPKTAQRLA---LHLAFHKEEAEALAEALEGIKRVRACRECGNLAEGELCPICQDEDR 75 Query: 90 PPAVMAAVDQA-----LKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNV 144 +++A V+ L+ G L + G G ++ G F Sbjct: 76 DRSLLAVVESVADLYALERSGEFRGLYHVLGGALNPLEGIGPKE-------LNLEGLFRR 128 Query: 145 SRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRV 203 + E +V T+ +A +LA E + +RV Sbjct: 129 LEGVEE---------VVLATSMTVEG---------------EATALYLAEELKKRGVRV 163 >2XHZ-A nrPDB Length = 183 Score = 27.2 bits (59), Expect = 7.6, Method: Composition-based stats. Identities = 8/27 (29%), Positives = 12/27 (44%), Gaps = 1/27 (3%) Query: 27 RDKVAFI-TGGGSGIGFRIAEIFMRHG 52 + KV + G IG ++A F G Sbjct: 49 KGKVVVMGMGASGHIGRKMAATFASTG 75 >2HTF-A nrPDB Length = 105 Score = 27.2 bits (59), Expect = 7.7, Method: Composition-based stats. Identities = 18/71 (25%), Positives = 31/71 (43%), Gaps = 1/71 (1%) Query: 19 HLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLT-AARKLAGATG 77 +L P + R + AF+TG GFR+ + H V+ S ++ R++A A Sbjct: 14 YLVEPRMGRSRRAFLTGLARSKGFRVLDACSSEATHVVMEETSAEEAVSWQERRMAAAPP 73 Query: 78 RRCLPLSMDVR 88 P +D+ Sbjct: 74 GCTPPALLDIS 84 >4BKO-A nrPDB Length = 417 Score = 27.2 bits (59), Expect = 7.8, Method: Composition-based stats. Identities = 15/105 (14%), Positives = 30/105 (28%), Gaps = 12/105 (11%) Query: 29 KVAFITGGGSGIGFRIAEIFMRHGCHT---VIASRSLPRVL---------TAARKLAGAT 76 K + G +G G V R+ A A A Sbjct: 62 KKVLVIGASTGYGLAARIAAAFGAGAATLGVFFERAPADAKPGTAGWYNSAAFHDEAAAR 121 Query: 77 GRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCP 121 G + ++ D + +D ++ G++D+++ A Sbjct: 122 GLQATSVNGDAFSDEIKHKTIDAIRRDLGQVDLVVYSVAAPRRTH 166 >1OFI-A nrPDB Length = 310 Score = 27.2 bits (59), Expect = 8.3, Method: Composition-based stats. Identities = 9/58 (15%), Positives = 22/58 (37%), Gaps = 5/58 (8%) Query: 213 GTEGLRRLGGPQASLSTKVTASPLQRLGNKTE-IAHSVLYLASPLASYVTGAVLVADG 269 T+ ++++ ++ K +RL E + + + AS + G + D Sbjct: 236 TTDAVKKIAEAAFRVNEKTENIGARRLHTVMERLMDKISFSASD----MNGQTVNIDA 289 >1IE3-A nrPDB Length = 312 Score = 27.2 bits (59), Expect = 8.5, Method: Composition-based stats. Identities = 8/20 (40%), Positives = 11/20 (55%), Gaps = 1/20 (5%) Query: 29 KVAFITGGGSGIGFRIAEIF 48 KVA + G GIG +A + Sbjct: 2 KVA-VLGAAGGIGQALALLL 20 >5IOB-A nrPDB Length = 348 Score = 27.2 bits (59), Expect = 8.7, Method: Composition-based stats. Identities = 9/49 (18%), Positives = 15/49 (30%) Query: 156 HGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVN 204 GG + T LG+ + V+ + L + VN Sbjct: 93 EGGRVQRATNILGDFPSPRVMAQTMTPEQVEDLAEILGTGLAAHGVTVN 141 >4Y4N-A nrPDB Length = 286 Score = 27.2 bits (59), Expect = 9.6, Method: Composition-based stats. Identities = 11/34 (32%), Positives = 15/34 (44%), Gaps = 2/34 (5%) Query: 30 VAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLP 63 VA + GG SG+ A + G V+ R L Sbjct: 55 VAIVGGGPSGL--TAARYIAKEGYKVVVLERHLA 86 >5MH6-A nrPDB Length = 308 Score = 27.2 bits (59), Expect = 9.8, Method: Composition-based stats. Identities = 12/50 (24%), Positives = 18/50 (36%), Gaps = 4/50 (8%) Query: 14 LPAYRHLFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLP 63 LP Y P L + + G G+ +G + + G V RS Sbjct: 124 LPRYEE---PFTLAGERVCVVGLGT-LGRGVVDRAAALGMEVVGVRRSGD 169 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.314 0.147 0.420 Lambda K H 0.267 0.0452 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,470,991 Number of Sequences: 36641 Number of extensions: 540777 Number of successful extensions: 3275 Number of sequences better than 10.0: 419 Number of HSP's better than 10.0 without gapping: 422 Number of HSP's successfully gapped in prelim test: 175 Number of HSP's that attempted gapping in prelim test: 2002 Number of HSP's gapped (non-prelim): 649 length of query: 292 length of database: 10,336,785 effective HSP length: 96 effective length of query: 196 effective length of database: 6,819,249 effective search space: 1336572804 effective search space used: 1336572804 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 59 (27.2 bits)