BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9NR50 (452 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6EZO-E nrPDB 928 0.0 5B04-E nrPDB 214 5e-56 6I7T-I nrPDB 83 2e-16 6JLY-I nrPDB 67 1e-11 6I7T-G nrPDB 64 2e-10 1MC3-A nrPDB 53 3e-07 3ZLK-A nrPDB 52 6e-07 5IFY-A nrPDB 52 6e-07 1LVW-A nrPDB 52 6e-07 6N0U-A nrPDB 50 1e-06 4HO3-A nrPDB 50 2e-06 5IDS-A nrPDB 50 2e-06 1H5S-D nrPDB 50 2e-06 3PKP-A nrPDB 50 3e-06 6B5K-A nrPDB 49 5e-06 6O85-A nrPDB 49 7e-06 4Y7U-A nrPDB 48 8e-06 5Z09-A nrPDB 47 1e-05 1JYL-A nrPDB 46 3e-05 4D48-A nrPDB 45 1e-04 2E3D-A nrPDB 44 1e-04 3JUK-A nrPDB 43 3e-04 1WVC-A nrPDB 42 5e-04 2UX8-A nrPDB 42 7e-04 4JD0-A nrPDB 41 0.001 5XHW-A nrPDB 40 0.002 5I1F-A nrPDB 40 0.002 4ECM-A nrPDB 40 0.003 5VE7-A nrPDB 40 0.003 5J49-A nrPDB 40 0.003 5VMK-A nrPDB 37 0.025 4CVH-A nrPDB 35 0.054 3FWW-A nrPDB 34 0.12 2V0L-A nrPDB 34 0.12 1VPA-A nrPDB 34 0.12 3F1C-A nrPDB 33 0.33 4MND-A nrPDB 30 1.8 4BWP-A nrPDB 30 1.9 4R36-A nrPDB 30 2.4 2PA4-A nrPDB 30 2.7 2QKX-A nrPDB 29 3.4 4G3P-A nrPDB 29 3.7 2XWM-A nrPDB 29 3.8 3JYO-A nrPDB 28 5.6 5MNI-E nrPDB 28 7.4 3PDK-A nrPDB 28 9.5 >6EZO-E nrPDB Length = 452 Score = 928 bits (2399), Expect = 0.0, Method: Compositional matrix adjust. Identities = 452/452 (100%), Positives = 452/452 (100%) Query: 1 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQ 60 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQ Sbjct: 1 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQ 60 Query: 61 KALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEVVDL 120 KALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEVVDL Sbjct: 61 KALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEVVDL 120 Query: 121 FRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMANEADLDEEL 180 FRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMANEADLDEEL Sbjct: 121 FRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMANEADLDEEL 180 Query: 181 VIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYLVRKQFSSA 240 VIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYLVRKQFSSA Sbjct: 181 VIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYLVRKQFSSA 240 Query: 241 SSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWEDLSRSQVRC 300 SSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWEDLSRSQVRC Sbjct: 241 SSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWEDLSRSQVRC 300 Query: 301 YVHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPPVHSSAQIVSKHLVGVDSLIGP 360 YVHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPPVHSSAQIVSKHLVGVDSLIGP Sbjct: 301 YVHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPPVHSSAQIVSKHLVGVDSLIGP 360 Query: 361 ETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEGSNIQGSVICNNAVIEKGAD 420 ETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEGSNIQGSVICNNAVIEKGAD Sbjct: 361 ETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEGSNIQGSVICNNAVIEKGAD 420 Query: 421 IKDCLIGSGQRIEAKAKRVNEVIVGNDQLMEI 452 IKDCLIGSGQRIEAKAKRVNEVIVGNDQLMEI Sbjct: 421 IKDCLIGSGQRIEAKAKRVNEVIVGNDQLMEI 452 >5B04-E nrPDB Length = 458 Score = 214 bits (546), Expect = 5e-56, Method: Compositional matrix adjust. Identities = 142/443 (32%), Positives = 233/443 (52%), Gaps = 50/443 (11%) Query: 1 MEFQAVVMAVGGGSRMTDLTSS--IPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRD 58 +EFQAVV A G G+ + LT S +PK LLP+GNKP++ YPL LE GF I++ + Sbjct: 37 IEFQAVVFA-GFGNSLYPLTGSDALPKALLPIGNKPMLHYPLYWLEAAGFTSAILICMEE 95 Query: 59 VQKALCA------EFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDV 112 + + A E M++ + I DD+ +AD+LR + +K D + LSCD I + Sbjct: 96 AEAHINAWLRSGYEGHMRIHVEAPTILDDSK-SSADALRAVSHLIKNDFVCLSCDSIVGL 154 Query: 113 ALHEVVDLFRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMAN 172 + V+D FR D A+ + E + Q K ++ + IG++ RLL+ + Sbjct: 155 PPYTVLDKFR-LDNPSALAVYSPVLKYEHITSQS---KEIDAKQLIGIEEKTSRLLYAKS 210 Query: 173 EADLDEELVIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYL 232 AD+ + + S+L KHPR+ +T L DAH++ K +++D + E SI+SIR +LIPYL Sbjct: 211 SADVGSDFTFRMSLLWKHPRVTLNTNLSDAHIFVFKHWVIDLIREKESISSIRGDLIPYL 270 Query: 233 VRKQFSSASSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWED 292 V+ Q+ Q+ +E +I F+ N N+ YD Sbjct: 271 VKCQY-----QKSFTVRE-----------NIQRFLSSPN--NIDNYDG-----------G 301 Query: 293 LSRSQVRCYVHIMKEG-LCSRVSTLGLYMEANRQVPKLLSALCPEEPPVHSSAQIVSKHL 351 LS +++ I K+G +CSR + L Y E N+ + K L PE+ V + + L Sbjct: 302 LSSQEIKINALIAKDGIICSRANNLPNYFELNKCIAK----LTPEQRLV--DVTVSERAL 355 Query: 352 VGVDSLIGPETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEGSNIQGSVICN 411 VG D ++ T I + S+IK+S+IG +C+I V ++N +LM+++ VE+G ++ ++ + Sbjct: 356 VGADCMVNEGTTIKDNSNIKKSIIGKNCVIGKGVVVSNSILMDNIVVEDGVRLESCIVAS 415 Query: 412 NAVIEKGADIKDCLIGSGQRIEA 434 A I + +++C IG R+EA Sbjct: 416 GAQIGAKSKLRECEIGVDHRVEA 438 >6I7T-I nrPDB Length = 578 Score = 83.2 bits (204), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 111/486 (22%), Positives = 205/486 (42%), Gaps = 85/486 (17%) Query: 20 TSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRD----VQKALCA-------EFK 68 ++ +PK LLP+GN+P+I Y L+ ++ F+E+ VV D ++ L + +F+ Sbjct: 61 STRLPKALLPIGNRPMIEYVLDWCDQADFKEISVVAPVDEIELIESGLTSFLSLRKQQFE 120 Query: 69 MKMKP--------------DIVCIPDDADMGTADSL-RYIYPKLKTDVLVLSCDLITDVA 113 + K I IP A+ T +SL + + P++ D ++L CD +TD+ Sbjct: 121 LIYKALSNSNHSHHLQDPKKINFIPSKAN-STGESLQKELLPRINGDFVILPCDFVTDIP 179 Query: 114 LHEVVDLFRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFI----GVDSTGKRLL- 168 +VD FR D + + ++S++ +K ++K +Q+ F DS + +L Sbjct: 180 PQVLVDQFRNRDDNNLAMTIYYKNSLDSSIDKKQQQKQKQQQFFTVYSENEDSERQPILL 239 Query: 169 --FMANEADLDEELVIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRS 226 + + + L I+ +L +P + T L+++ +Y + L Sbjct: 240 DVYSQRDVTKTKYLQIRSHLLWNYPNLTVSTKLLNSFIYFCSFELCQLL----------- 288 Query: 227 ELIPYLVRKQFSSASSQQGQEEKEE---------------DLKKKELKSLDIYSFIKEAN 271 +L P + +Q S G ++++ D K S+ ++ K+ N Sbjct: 289 KLGPQSMSRQASFKDPFTGNQQQQNPPTTDDDEDRNHDDDDDYKPSATSIQP-TYFKKKN 347 Query: 272 TLNLAPYDACWNACRGDRWEDLSRSQVRCYVH-----------IMKEGLCSRVSTLGLYM 320 L L P + N + DLSR R + H + E L R + L YM Sbjct: 348 DLILDPINC--NKSLSKVFRDLSR---RSWQHSKPREPIGIFILPNETLFIRANNLNAYM 402 Query: 321 EANRQVPKLLS-ALCPEEPPVHSSAQIVSKHLVGVDSLIGPETQIGEKSSIKRSVIGSSC 379 +ANR V K+ S + + + S+A +G D+++ P+ QI S++K SV+G+ Sbjct: 403 DANRFVLKIKSQTMFTKNIQIQSAA-------IGADAIVDPKCQISAHSNVKMSVLGTQA 455 Query: 380 LIKDRVTITNCLLMNSVTVEEGSNIQGSVICNNAVIEKGADIKDCLIGSGQRIEAKAKRV 439 I R + LL V + + ++ +I A I + +C I +E K Sbjct: 456 NIGSRCRVAGSLLFPGVHLGDEVILENCIIGPMAKIGSKCKLSNCYIEGHYVVEPKNNFK 515 Query: 440 NEVIVG 445 E + Sbjct: 516 GETLAN 521 >6JLY-I nrPDB Length = 678 Score = 67.0 bits (162), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 96/478 (20%), Positives = 185/478 (38%), Gaps = 109/478 (22%) Query: 3 FQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQKA 62 QA+V++ R LT P+ LLP+ N PLI Y L G +EV V Sbjct: 18 LQAIVLSDSYNYRFRPLTLDKPRCLLPLANTPLIEYTFEFLALAGVQEVYVFCC--AHAG 75 Query: 63 LCAEFKMKMKPDIVCIPDDAD-------MGTADSLRYIYPK--LKTDVLVLSCDLITDVA 113 E+ K K ++ P + + D+LR + K + +D +++S D++++V Sbjct: 76 QIREYIEKSKWNLPSSPFSVNTIVSRESLSVGDALRELDSKQLITSDFILVSGDVVSNVP 135 Query: 114 LHEVVDLFRAY-----DASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLL 168 L+EV+ R +A + M++R E P + + + E F+ T + + Sbjct: 136 LNEVLKEHRKRREDDKNAIMTMVVR------EASPFHRTRAR-TESSVFVIDKKTSQCVH 188 Query: 169 FMANEADLDEELVIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSEL 228 + ANE + + I +H + L+D + I S Sbjct: 189 YQANERG-KHYVSMDPEIFNEHEELEVRNDLIDCQI------------------DICSND 229 Query: 229 IPYLVRKQFSSASSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGD 288 +P L + F +D++K F+ T Sbjct: 230 VPALFTENFDY-----------QDIRK---------DFVYGVLT---------------- 253 Query: 289 RWEDLSRSQVRCYVHIMKEGLCSRVSTLGLYMEANRQV-PKLLSALCPEEPPVHSS---- 343 DL ++ C H+ KE +RV +L Y ++ V + + P+ ++ + Sbjct: 254 --SDLLGKKIHC--HVAKENYAARVRSLQTYDAISKDVLSRWVYPFVPDSNLLNQTFSYQ 309 Query: 344 -AQIVSKH--------LVGVDSLIGPETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMN 394 QI + ++ +LIG T++G+ S + ++IG +C I +I + L Sbjct: 310 RHQIYKEEDVVLARSCIIKARTLIGAYTKVGDASVVANTIIGRNCTIGSNCSIDSAFLWE 369 Query: 395 SVTVEEGSNIQGSVICNNAVIEKGADIKD-CLIGSGQRIEAKAKRVNEVIVGNDQLME 451 V + + I +++ N+ I I+D ++ +G V++G++ ++E Sbjct: 370 DVVIGDNCRIGKAILANSVKIGNNCSIEDGAIVAAG------------VVIGDNTIIE 415 >6I7T-G nrPDB Length = 712 Score = 63.9 bits (154), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 93/462 (20%), Positives = 180/462 (38%), Gaps = 98/462 (21%) Query: 3 FQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQKA 62 QAVV+ +R LT+ P+ LLP+ N PLI Y L L + G EV ++ + + Sbjct: 27 LQAVVLTDSYETRFMPLTAVKPRCLLPLANVPLIEYTLEFLAKAGVHEVFLICSSHANQI 86 Query: 63 L-----------CAEFKMK--MKPDIVCIPDDADMGTADSLRYIYPK--LKTDVLVLSCD 107 + FK+ M P+ C T D +R + + + D +++S D Sbjct: 87 NDYIENSKWNLPWSPFKITTIMSPEARC--------TGDVMRDLDNRGIITGDFILVSGD 138 Query: 108 LITDVALHEVVDLFRAYDASLAMLMRKGQDSIEPVPGQKG----KKKAVEQRDFIGVDST 163 ++T++ ++++ + + + +D I + K K + +E F+ +D + Sbjct: 139 VLTNIDFSKMLEFHKK-------MHLQDKDHISTMCLSKASTYPKTRTIEPAAFV-LDKS 190 Query: 164 GKRLLFMAN----EADLDEELVIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENG 219 R ++ + + + I +L L+D + ++ EN Sbjct: 191 TSRCIYYQDLPLPSSREKTSIQIDPELLDNVDEFVIRNDLIDCRIDICTSHVPLIFQENF 250 Query: 220 SITSIRSELIPYLVRKQFSSASSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNL---A 276 S+R++ + ++ +S G+ IY+++ + + + Sbjct: 251 DYQSLRTDFVKGVI------SSDILGKH---------------IYAYLTDEYAVRVESWQ 289 Query: 277 PYDACWNACRGDRWEDLSRSQVRCYVHIMKEGLCSRVSTLGLYMEANRQVPK----LLSA 332 YD G RW CY ++ S + Y +R + K +L+ Sbjct: 290 TYDTISQDFLG-RW---------CYPLVLD----SNIQDDQTYSYESRHIYKEKDVVLAQ 335 Query: 333 LCPEEPPVHSSAQIVSKHLVGVDSLIGPETQIGEKSSIKRSVIGSSCLIKDRVTITNCLL 392 C +G + IG T+IGE + I+ SVIG +C I + + I N + Sbjct: 336 SCK----------------IGKCTAIGSGTKIGEGTKIENSVIGRNCQIGENIRIKNSFI 379 Query: 393 MNSVTVEEGSNIQGSVICNNAVIEKGADIKD-CLIGSGQRIE 433 + + S I S+I +NA + + D C+IG +I+ Sbjct: 380 WDDCIIGNNSIIDHSLIASNATLGSNVRLNDGCIIGFNVKID 421 >1MC3-A nrPDB Length = 296 Score = 52.8 bits (125), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 20/53 (37%), Positives = 38/53 (71%) Query: 4 QAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTT 56 + +++A G G+R+ +T + K LLP+ +KP+I+YPL++L G E++++TT Sbjct: 5 KGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITT 57 >3ZLK-A nrPDB Length = 303 Score = 52.0 bits (123), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 22/56 (39%), Positives = 39/56 (69%) Query: 1 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTT 56 M+ + +++A G G+R+ T +I K LLPV +KP+I+YPL+ L G E+++++T Sbjct: 11 MKRKGIILAGGSGTRLHPATLAISKQLLPVYDKPMIYYPLSTLMLAGIREILIIST 66 >5IFY-A nrPDB Length = 305 Score = 52.0 bits (123), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 21/56 (37%), Positives = 39/56 (69%) Query: 1 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTT 56 M + +++A G G+R+ +T ++ K LLPV +KP+I+YPL+ L G +V++++T Sbjct: 9 MARKGIILAGGSGTRLYPITHAVSKQLLPVYDKPMIYYPLSTLMIAGIRDVLIIST 64 >1LVW-A nrPDB Length = 295 Score = 51.6 bits (122), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 21/57 (36%), Positives = 42/57 (73%), Gaps = 1/57 (1%) Query: 4 QAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTT-RDV 59 + +V+A G G+R+ +T ++ K LLP+ +KP+I+YPL++L G ++++++T RD+ Sbjct: 5 KGIVLAGGSGTRLYPITRAVSKQLLPIYDKPMIYYPLSVLMLAGIRDILIISTPRDL 61 >6N0U-A nrPDB Length = 305 Score = 50.4 bits (119), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 21/56 (37%), Positives = 38/56 (67%) Query: 1 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTT 56 M + +++A G G+R+ +T + K LLPV +KP+I+YPL+ L G +V++++T Sbjct: 9 MARKGIILAGGSGTRLYPITHVVSKQLLPVYDKPMIYYPLSTLMVAGIRDVLIIST 64 >4HO3-A nrPDB Length = 297 Score = 50.1 bits (118), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 18/53 (33%), Positives = 39/53 (73%) Query: 4 QAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTT 56 + ++++ G G+R+ LT + K LLPV +KP+++YPL++L G +++++++T Sbjct: 2 KGIILSGGSGTRLYPLTKVVSKQLLPVYDKPMVYYPLSVLMLAGIKDILIIST 54 >5IDS-A nrPDB Length = 302 Score = 50.1 bits (118), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 22/53 (41%), Positives = 37/53 (69%) Query: 4 QAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTT 56 + +++A G G+R+ T +I K LLPV +KP+I+YPL+ L G +V+V++T Sbjct: 13 KGIILAGGSGTRLHPATLAISKQLLPVYDKPMIYYPLSTLMLAGMRDVLVIST 65 >1H5S-D nrPDB Length = 293 Score = 50.1 bits (118), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 24/83 (28%), Positives = 49/83 (59%), Gaps = 12/83 (14%) Query: 4 QAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTT-RDV--- 59 + +++A G G+R+ +T ++ K LLP+ +KP+I+YPL+ L G ++++++T +D Sbjct: 5 KGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPRF 64 Query: 60 --------QKALCAEFKMKMKPD 74 Q L ++K++ PD Sbjct: 65 QQLLGDGSQWGLNLQYKVQPSPD 87 >3PKP-A nrPDB Length = 292 Score = 49.7 bits (117), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 18/53 (33%), Positives = 38/53 (71%) Query: 4 QAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTT 56 + +++A G G+R+ +T ++ K LLP+ +KP+I+YPL+ L G ++++++T Sbjct: 5 KGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIIST 57 >6B5K-A nrPDB Length = 296 Score = 48.5 bits (114), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 21/53 (39%), Positives = 35/53 (66%) Query: 4 QAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTT 56 + +++A G G+R+ +T I K LLPV +KP+I+YPL L G ++ ++TT Sbjct: 2 RGIILAGGSGTRLYPITMGISKQLLPVYDKPMIYYPLTTLMMAGIRDIQLITT 54 >6O85-A nrPDB Length = 721 Score = 48.5 bits (114), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 38/139 (27%), Positives = 61/139 (43%), Gaps = 17/139 (12%) Query: 301 YVHIMKEGLCSRVSTLGLYMEANRQV-PKLLSALCPEEPPVHSSAQ--IVSKH------- 350 ++H+ + +RVS L +Y V + + L PE S+ Q S+H Sbjct: 288 HMHVTAKEYGARVSNLHMYSAVCADVIRRWVYPLTPEANFTDSTTQSCTHSRHNIYRGPE 347 Query: 351 -------LVGVDSLIGPETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEGSN 403 ++ + L+G T IG I SVIG C I D V + L V V G+ Sbjct: 348 VSLGHGSILEENVLLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQGVRVAAGAQ 407 Query: 404 IQGSVICNNAVIEKGADIK 422 I S++C+NA +++ +K Sbjct: 408 IHQSLLCDNAEVKERVTLK 426 >4Y7U-A nrPDB Length = 231 Score = 48.1 bits (113), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 23/50 (46%), Positives = 31/50 (62%) Query: 4 QAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIV 53 +A+++A G G RM LT PKPL+PV +PLI Y L L G EV++ Sbjct: 2 KAMILAAGKGERMRPLTLHTPKPLVPVAGQPLIEYHLRALAAAGVTEVVI 51 >5Z09-A nrPDB Length = 409 Score = 47.4 bits (111), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 27/106 (25%), Positives = 54/106 (50%), Gaps = 6/106 (5%) Query: 4 QAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQKAL 63 +A ++A G G R+ +T + PK +P+ +KPLI Y + L + G ++ V+ + ++ Sbjct: 2 KAFILAAGSGERLEPITHTRPKAFVPILSKPLIEYQIEYLRKCGIRDITVIVSSKNKEY- 60 Query: 64 CAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLI 109 F+ K+K + D GT ++ + K + L+++ DL Sbjct: 61 ---FEKKLKEISIVTQKDDIKGTGAAI--LSAKFNDEALIINGDLF 101 >1JYL-A nrPDB Length = 254 Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 19/52 (36%), Positives = 33/52 (63%) Query: 4 QAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVT 55 +A+++A G G+R+ LT + PK L+ V KPLI Y + L+ G ++I++ Sbjct: 27 KAIILAAGLGTRLRPLTENTPKALVQVNQKPLIEYQIEFLKEKGINDIIIIV 78 >4D48-A nrPDB Length = 302 Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 22/52 (42%), Positives = 33/52 (63%) Query: 4 QAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVT 55 +AV+ G G+RM T +IPK +LP+ +KPLI Y +N G E+++VT Sbjct: 10 KAVIPVAGLGTRMLPATKAIPKEMLPLVDKPLIQYVVNECIAAGINEIVLVT 61 >2E3D-A nrPDB Length = 302 Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 22/52 (42%), Positives = 33/52 (63%) Query: 4 QAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVT 55 +AV+ G G+RM T +IPK +LP+ +KPLI Y +N G E+++VT Sbjct: 10 KAVIPVAGLGTRMLPATKAIPKEMLPLVDKPLIQYVVNECIAAGITEIVLVT 61 >3JUK-A nrPDB Length = 281 Score = 43.1 bits (100), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 20/50 (40%), Positives = 30/50 (60%) Query: 9 AVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRD 58 A G G+R +T +IPK +LP+ +KPLI Y + G E + +VT R+ Sbjct: 9 AAGYGTRFLPITKTIPKEMLPIVDKPLIQYAVEEAMEAGCEVMAIVTGRN 58 >1WVC-A nrPDB Length = 259 Score = 42.0 bits (97), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 17/53 (32%), Positives = 35/53 (66%) Query: 1 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIV 53 M +AV++A G G+R+++ T PKP++ +G KP++W+ + + G ++ I+ Sbjct: 1 MASKAVILAGGLGTRLSEETIVKPKPMVEIGGKPILWHIMKMYSVHGIKDFII 53 >2UX8-A nrPDB Length = 297 Score = 41.6 bits (96), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 21/54 (38%), Positives = 32/54 (59%) Query: 4 QAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTR 57 +AV G G+R T ++PK +LPV ++PLI Y ++ G E++I VT R Sbjct: 16 KAVFPVAGLGTRFLPATKAMPKEMLPVVDRPLIQYAVDEAVEAGIEQMIFVTGR 69 >4JD0-A nrPDB Length = 251 Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust. Identities = 27/106 (25%), Positives = 51/106 (48%), Gaps = 6/106 (5%) Query: 4 QAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTT---RDVQ 60 +A+V+A G G R+ +T +PK L+ YP+ L + G E ++V + RD+ Sbjct: 13 EAIVLASGAGKRLRSVTGDVPKVFYRFDGCELVKYPMISLMKNGVERFVLVVSEGYRDLG 72 Query: 61 KALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSC 106 + + + ++ IV ++G A S P ++++ LSC Sbjct: 73 EKVLNDLGVE---GIVVENKKVELGNAYSFFLSEPYVESEKFFLSC 115 >5XHW-A nrPDB Length = 237 Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust. Identities = 15/51 (29%), Positives = 31/51 (60%) Query: 3 FQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIV 53 + V++A G G+R+ ++ IPKP++ + KP ++ + LE G + +I+ Sbjct: 14 YDVVILAGGLGTRLKSVSGDIPKPMVDISGKPFLYRLMEYLEDQGVQRIIL 64 >5I1F-A nrPDB Length = 302 Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust. Identities = 22/54 (40%), Positives = 29/54 (53%) Query: 4 QAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTR 57 +AV G G+R T + PK +LPV +KPLI Y + G E+I VT R Sbjct: 14 KAVFPVAGLGTRFLPATKASPKEMLPVVDKPLIQYAVEEAIEAGITEMIFVTGR 67 >4ECM-A nrPDB Length = 269 Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust. Identities = 16/55 (29%), Positives = 35/55 (63%) Query: 4 QAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRD 58 + +++A G GSR+ +T K LLPVG P+I++ + L++ +++++T ++ Sbjct: 26 KGIILAGGTGSRLYPITKVTNKHLLPVGRYPMIYHAVYKLKQCDITDIMIITGKE 80 >5VE7-A nrPDB Length = 302 Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust. Identities = 22/54 (40%), Positives = 29/54 (53%) Query: 4 QAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTR 57 +AV G G+R T + PK +LPV +KPLI Y + G E+I VT R Sbjct: 14 KAVFPVAGLGTRFLPATKASPKEMLPVVDKPLIQYAVEEAIAAGITEMIFVTGR 67 >5J49-A nrPDB Length = 301 Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust. Identities = 21/54 (38%), Positives = 29/54 (53%) Query: 4 QAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTR 57 +AV G G+R T + PK +LP+ +KPLI Y + G E+I VT R Sbjct: 14 KAVFPVAGLGTRFLPATKASPKEMLPIVDKPLIQYAVEEAMAAGITEMIFVTGR 67 >5VMK-A nrPDB Length = 462 Score = 36.6 bits (83), Expect = 0.025, Method: Compositional matrix adjust. Identities = 37/164 (22%), Positives = 70/164 (42%), Gaps = 18/164 (10%) Query: 1 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTR--- 57 M +++A G G+RM S +PK L P+ +PL+ + + +++ E +I + Sbjct: 9 MSTTVIILAAGKGTRMR---SQLPKVLQPLAGRPLLGHVIKTAKQLLAENIITIYGHGGD 65 Query: 58 DVQKALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTD--VLVLSCD--LITDVA 113 V+K E +I + +GT +++ P L D L+L D L+ Sbjct: 66 HVKKTFAQE-------NIQWVEQAEQLGTGHAVQMTLPVLPKDGISLILYGDVPLVRQTT 118 Query: 114 LHEVVDLFRAYDASLAMLMRKGQDSIEPVPGQKGKKKA-VEQRD 156 L +++++ + L + Q GK +A VE +D Sbjct: 119 LEQLIEVSNKTGIGMITLHVDNPTGYGRIVRQDGKIQAIVEHKD 162 Score = 32.7 bits (73), Expect = 0.33, Method: Compositional matrix adjust. Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 7/74 (9%) Query: 374 VIGSSCLIKDRVTI-TNCLLMNSVTVEEGSNIQGSVICNNAVIEKGADIKDCLIGSGQRI 432 +I +C + D V I C+L N+ T+ G+ +Q + + AV+ + + IG R+ Sbjct: 284 IIEGNCELGDFVEIGAGCILKNT-TIAAGTKVQAYSVFDGAVVGE-----NTQIGPFARL 337 Query: 433 EAKAKRVNEVIVGN 446 AK NEV +GN Sbjct: 338 RPGAKLANEVHIGN 351 >4CVH-A nrPDB Length = 411 Score = 35.4 bits (80), Expect = 0.054, Method: Compositional matrix adjust. Identities = 26/70 (37%), Positives = 37/70 (52%), Gaps = 7/70 (10%) Query: 5 AVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTR----DVQ 60 AV+ A G G RM T PK P+ +PLI Y L LERV + + IVV +V Sbjct: 9 AVLPAGGCGERMGVPT---PKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENMEVM 65 Query: 61 KALCAEFKMK 70 K++ +++ K Sbjct: 66 KSIIQKYQHK 75 >3FWW-A nrPDB Length = 456 Score = 34.3 bits (77), Expect = 0.12, Method: Compositional matrix adjust. Identities = 26/108 (24%), Positives = 51/108 (47%), Gaps = 15/108 (13%) Query: 6 VVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRD---VQKA 62 V++A G G+RM S +PK L P+ KP++ + ++ ++G + V +V ++K Sbjct: 9 VILAAGKGTRMY---SDLPKVLHPLAGKPMVQHVIDAAMKLGAQHVHLVYGHGGELLKKT 65 Query: 63 LCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLK--TDVLVLSCDL 108 L P + + +GT +++ P D+L+L D+ Sbjct: 66 LA-------DPSLNWVLQAEQLGTGHAMQQAAPHFADDEDILMLYGDV 106 >2V0L-A nrPDB Length = 456 Score = 34.3 bits (77), Expect = 0.12, Method: Compositional matrix adjust. Identities = 29/123 (23%), Positives = 60/123 (48%), Gaps = 15/123 (12%) Query: 3 FQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTR--DVQ 60 AV++A G G+RM S +PK L + KP++ + ++ ++G E + ++ D+ Sbjct: 6 LSAVILAAGKGTRMY---SDLPKVLHTIAGKPMVKHVIDTAHQLGSENIHLIYGHGGDLM 62 Query: 61 KALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLK--TDVLVLSCD--LITDVALHE 116 + A ++ + +GTA +++ P K +++VL D LIT L + Sbjct: 63 RTHLANEQVN------WVLQTEQLGTAHAVQQAAPFFKDNENIVVLYGDAPLITKETLEK 116 Query: 117 VVD 119 +++ Sbjct: 117 LIE 119 >1VPA-A nrPDB Length = 234 Score = 34.3 bits (77), Expect = 0.12, Method: Compositional matrix adjust. Identities = 18/55 (32%), Positives = 33/55 (60%), Gaps = 4/55 (7%) Query: 5 AVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLN-LLERVGFEEVIVVTTRD 58 A+++A G G RM++ ++PK L + + L YPL+ L+ + V++VT R+ Sbjct: 16 AILLAAGKGERMSE---NVPKQFLEIEGRMLFEYPLSTFLKSEAIDGVVIVTRRE 67 >3F1C-A nrPDB Length = 246 Score = 32.7 bits (73), Expect = 0.33, Method: Compositional matrix adjust. Identities = 29/130 (22%), Positives = 64/130 (49%), Gaps = 10/130 (7%) Query: 5 AVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPL-NLLERVGFEEVIVVTTRDVQKAL 63 A ++A G G+RM ++ S+PK LP+ KP+I + + + F+++++ + ++ Sbjct: 6 AQILAGGKGTRMGNV--SMPKQFLPLNGKPIIVHTVEKFILNTRFDKILISSPKEWMNHA 63 Query: 64 CAEFKMKMKPD-IVCIP--DDADMGTADSLRYIYPK--LKTDVLVLSCDLITDVALHEVV 118 K + D IV I +D + + +R++ L D ++++ D + H ++ Sbjct: 64 EDNIKKYISDDRIVVIEGGEDRNETIMNGIRFVEKTYGLTDDDIIVTHDAVRPFLTHRII 123 Query: 119 DLFRAYDASL 128 + DA+L Sbjct: 124 E--ENIDAAL 131 >4MND-A nrPDB Length = 479 Score = 30.4 bits (67), Expect = 1.8, Method: Compositional matrix adjust. Identities = 19/54 (35%), Positives = 30/54 (55%), Gaps = 5/54 (9%) Query: 4 QAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTR 57 +AV++A G G+R+ +PKPL+ VG +I + LL E I+V +R Sbjct: 42 KAVILAAGLGTRL----GGVPKPLVRVGGCEIILRTMKLLSP-HVSEFIIVASR 90 >4BWP-A nrPDB Length = 448 Score = 30.0 bits (66), Expect = 1.9, Method: Compositional matrix adjust. Identities = 21/87 (24%), Positives = 47/87 (54%), Gaps = 6/87 (6%) Query: 207 LKKYIVDFLMENGSITSIRSELIPYLVRKQFSSASSQQGQEEKEEDLKKKELKSLDIYSF 266 L+ +IV +L + S+ ++L+P + + ++ + Q + + +ED KE+++ +Y Sbjct: 289 LRNFIV-YLFTTNNRRSV-TDLMPMIGARFYTQLDALQSKIDMQEDELAKEMENGRLYRI 346 Query: 267 IKEANTLNLAP---YDACWNACRGDRW 290 + + N++N P D W+ GDR+ Sbjct: 347 LVKLNSINERPDFNLDCTWSET-GDRY 372 >4R36-A nrPDB Length = 275 Score = 30.0 bits (66), Expect = 2.4, Method: Compositional matrix adjust. Identities = 31/118 (26%), Positives = 53/118 (44%), Gaps = 16/118 (13%) Query: 340 VHSSAQIVSKHLVGVDSLIGPETQIGE-------KSSIKRSVIGSSCLIKDRVTITNCLL 392 + ++A I+ +G + I P IG K + IG + LI++ VTI Sbjct: 58 IMANANILYGSRIGNGNTIFPGAVIGAIPQDLKFKGEESTAEIGDNNLIRENVTI----- 112 Query: 393 MNSVTVEEGSNIQGSVICNNAVIEKGADIKDCLIGSGQRIEAKAKRVNEVIVGNDQLM 450 N T +G I G+ NN ++E D LIG+G + K E+I+ ++ ++ Sbjct: 113 -NRGTAAKGRTIVGN---NNLLMEGVHVAHDALIGNGCIVGNSTKMAGEIIIDDNAII 166 >2PA4-A nrPDB Length = 323 Score = 29.6 bits (65), Expect = 2.7, Method: Compositional matrix adjust. Identities = 15/31 (48%), Positives = 19/31 (61%) Query: 6 VVMAVGGGSRMTDLTSSIPKPLLPVGNKPLI 36 VV A G G+R T ++PK LLPV + P I Sbjct: 16 VVPAAGLGTRFLPATKTVPKELLPVVDTPGI 46 >2QKX-A nrPDB Length = 391 Score = 29.3 bits (64), Expect = 3.4, Method: Compositional matrix adjust. Identities = 34/134 (25%), Positives = 61/134 (45%), Gaps = 11/134 (8%) Query: 6 VVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQK--AL 63 +V+A G G+RM S PK L + + ++ + L+ + ++ + +IVV D Q+ L Sbjct: 12 LVLAAGPGTRMR---SDTPKVLHTLAGRSMLSHVLHAIAKLAPQRLIVVLGHDHQRIAPL 68 Query: 64 CAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTD----VLVLSCD--LITDVALHEV 117 E + I D +GT ++ L D V+V S D L+ L ++ Sbjct: 69 VGELADTLGRTIDVALQDRPLGTGHAVLCGLSALPDDYAGNVVVTSGDTPLLDADTLADL 128 Query: 118 VDLFRAYDASLAML 131 + RA A++ +L Sbjct: 129 IATHRAVSAAVTVL 142 >4G3P-A nrPDB Length = 501 Score = 29.3 bits (64), Expect = 3.7, Method: Compositional matrix adjust. Identities = 33/134 (24%), Positives = 61/134 (45%), Gaps = 11/134 (8%) Query: 6 VVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQK--AL 63 +V+A G G+RM S PK L + + ++ + L+ + ++ + +IVV D Q+ L Sbjct: 16 LVLAAGPGTRMR---SDTPKVLHTLAGRSMLSHVLHAIAKLAPQRLIVVLGHDHQRIAPL 72 Query: 64 CAEFKMKMKPDIVCIPDDADMGTADS----LRYIYPKLKTDVLVLSCD--LITDVALHEV 117 E + I D +GT + L + +V+V S D L+ L ++ Sbjct: 73 VGELADTLGRTIDVALQDRPLGTGHAVLCGLSALPDDYAGNVVVTSGDTPLLDADTLADL 132 Query: 118 VDLFRAYDASLAML 131 + RA A++ +L Sbjct: 133 IATHRAVSAAVTVL 146 >2XWM-A nrPDB Length = 223 Score = 29.3 bits (64), Expect = 3.8, Method: Compositional matrix adjust. Identities = 24/69 (34%), Positives = 33/69 (47%), Gaps = 6/69 (8%) Query: 1 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQ 60 M AVV A G G R L + PK + +G PL+ + L+ L G + IV+ V Sbjct: 1 MATVAVVPAAGSGER---LRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIA---VP 54 Query: 61 KALCAEFKM 69 AL E K+ Sbjct: 55 PALTDESKL 63 >3JYO-A nrPDB Length = 283 Score = 28.5 bits (62), Expect = 5.6, Method: Compositional matrix adjust. Identities = 25/97 (25%), Positives = 43/97 (44%), Gaps = 23/97 (23%) Query: 46 VGFEEVIVVTTRDVQKALCAE--------FKMKMKP----DIVCIPDDADMGTADSLRYI 93 VG E V+ V R ++ + A M P D+ C+ D +G + Sbjct: 175 VGREAVVGVDARGIEDVIAAADGVVNATPMGMPAHPGTAFDVSCLTKDHWVGDV-----V 229 Query: 94 YPKLKTDVL----VLSCDLI--TDVALHEVVDLFRAY 124 Y ++T++L L C+ + T +A+H+ VD FR + Sbjct: 230 YMPIETELLKAARALGCETLDGTRMAIHQAVDAFRLF 266 >5MNI-E nrPDB Length = 431 Score = 28.1 bits (61), Expect = 7.4, Method: Compositional matrix adjust. Identities = 12/29 (41%), Positives = 19/29 (65%) Query: 5 AVVMAVGGGSRMTDLTSSIPKPLLPVGNK 33 A+++A G G+R+ DLT+ KP + G K Sbjct: 22 ALILAGGRGTRLKDLTNKRAKPAVHFGGK 50 >3PDK-A nrPDB Length = 469 Score = 27.7 bits (60), Expect = 9.5, Method: Compositional matrix adjust. Identities = 20/59 (33%), Positives = 28/59 (47%), Gaps = 2/59 (3%) Query: 394 NSVTVEEGSNIQGSVICNNAVIEKGADIKDCLIGSGQRIEAKAKRVNEVIVGNDQLMEI 452 N + + +G + V EKGADI G G R+ A ++ N IV DQ+M I Sbjct: 229 NGMNINDGVGSTHPEVLAELVKEKGADIGLAFDGDGDRLIAVDEKGN--IVDGDQIMFI 285 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6EZO-E nrPDB 566 e-161 5B04-E nrPDB 400 e-112 6I7T-I nrPDB 358 4e-99 6I7T-G nrPDB 334 3e-92 6JLY-I nrPDB 320 1e-87 6O85-A nrPDB 213 1e-55 4JD0-A nrPDB 108 5e-24 5Z09-A nrPDB 107 9e-24 3ZLK-A nrPDB 100 2e-21 6N0U-A nrPDB 99 3e-21 1H5S-D nrPDB 99 4e-21 5IFY-A nrPDB 99 5e-21 3PKP-A nrPDB 98 8e-21 1WVC-A nrPDB 94 1e-19 5IDS-A nrPDB 93 2e-19 1LVW-A nrPDB 93 2e-19 1MC3-A nrPDB 91 9e-19 4HO3-A nrPDB 91 1e-18 6B5K-A nrPDB 89 4e-18 5I1F-A nrPDB 86 3e-17 4Y7U-A nrPDB 86 4e-17 2UX8-A nrPDB 84 2e-16 1JYL-A nrPDB 83 2e-16 5XHW-A nrPDB 83 2e-16 4D48-A nrPDB 80 2e-15 2E3D-A nrPDB 80 3e-15 3JUK-A nrPDB 79 4e-15 Sequences not found previously or not previously below threshold: 5J49-A nrPDB 85 6e-17 5VE7-A nrPDB 85 1e-16 4ECM-A nrPDB 72 5e-13 2V0L-A nrPDB 70 2e-12 1YP3-A nrPDB 69 5e-12 3FWW-A nrPDB 68 6e-12 5MNI-E nrPDB 67 1e-11 2OI7-A nrPDB 67 1e-11 5VMK-A nrPDB 66 4e-11 1HM0-A nrPDB 64 1e-10 4MND-A nrPDB 63 2e-10 2PA4-A nrPDB 60 2e-09 5W6J-A nrPDB 58 1e-08 1FWY-A nrPDB 54 1e-07 2X5Z-A nrPDB 51 9e-07 2XWM-A nrPDB 51 1e-06 3TWD-A nrPDB 51 1e-06 4IHG-A nrPDB 50 2e-06 1VPA-A nrPDB 49 3e-06 2CU2-A nrPDB 48 1e-05 2MZB-A nrPDB 48 1e-05 4E79-A nrPDB 46 2e-05 4G3P-A nrPDB 46 3e-05 2QKX-A nrPDB 46 3e-05 4JIS-A nrPDB 46 5e-05 3PMO-A nrPDB 45 7e-05 1XHD-A nrPDB 45 8e-05 3F1C-A nrPDB 45 8e-05 4CVH-A nrPDB 44 1e-04 1H7T-A nrPDB 44 1e-04 3TQD-A nrPDB 44 2e-04 3OAM-A nrPDB 43 2e-04 4MFG-A nrPDB 43 2e-04 3T57-A nrPDB 43 4e-04 5F42-A nrPDB 42 6e-04 3K8D-A nrPDB 42 6e-04 1VH3-A nrPDB 39 0.004 2XWN-A nrPDB 39 0.006 4NAK-A nrPDB 38 0.008 2QH5-A nrPDB 38 0.008 2VSI-A nrPDB 38 0.010 3JTJ-A nrPDB 37 0.017 4KT7-A nrPDB 37 0.019 4EQY-A nrPDB 37 0.020 3MQG-A nrPDB 36 0.039 3R0S-A nrPDB 36 0.045 3TIO-A nrPDB 36 0.047 5HS2-A nrPDB 35 0.060 2IUA-A nrPDB 35 0.064 3CJ8-A nrPDB 35 0.074 2PX7-A nrPDB 35 0.078 1VGT-A nrPDB 35 0.088 2JF2-A nrPDB 34 0.090 3R8Y-A nrPDB 34 0.13 5JXX-A nrPDB 34 0.15 4MYB-A nrPDB 34 0.15 3Q1X-A nrPDB 34 0.17 4E6U-A nrPDB 33 0.20 2Y6P-A nrPDB 33 0.37 5NW4-h nrPDB 32 0.46 5DEP-A nrPDB 32 0.62 6F1T-V nrPDB 31 0.77 4XWI-A nrPDB 31 1.0 3RH2-A nrPDB 31 1.5 1J2Z-A nrPDB 30 2.4 5FV4-A nrPDB 29 3.1 3OH0-A nrPDB 29 5.3 4R36-A nrPDB 28 6.6 1KK6-A nrPDB 28 6.7 5BN5-A nrPDB 28 8.7 3K4E-A nrPDB 28 9.3 >6EZO-E nrPDB Length = 452 Score = 566 bits (1457), Expect = e-161, Method: Composition-based stats. Identities = 452/452 (100%), Positives = 452/452 (100%) Query: 1 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQ 60 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQ Sbjct: 1 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQ 60 Query: 61 KALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEVVDL 120 KALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEVVDL Sbjct: 61 KALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEVVDL 120 Query: 121 FRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMANEADLDEEL 180 FRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMANEADLDEEL Sbjct: 121 FRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMANEADLDEEL 180 Query: 181 VIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYLVRKQFSSA 240 VIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYLVRKQFSSA Sbjct: 181 VIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYLVRKQFSSA 240 Query: 241 SSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWEDLSRSQVRC 300 SSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWEDLSRSQVRC Sbjct: 241 SSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWEDLSRSQVRC 300 Query: 301 YVHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPPVHSSAQIVSKHLVGVDSLIGP 360 YVHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPPVHSSAQIVSKHLVGVDSLIGP Sbjct: 301 YVHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPPVHSSAQIVSKHLVGVDSLIGP 360 Query: 361 ETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEGSNIQGSVICNNAVIEKGAD 420 ETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEGSNIQGSVICNNAVIEKGAD Sbjct: 361 ETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEGSNIQGSVICNNAVIEKGAD 420 Query: 421 IKDCLIGSGQRIEAKAKRVNEVIVGNDQLMEI 452 IKDCLIGSGQRIEAKAKRVNEVIVGNDQLMEI Sbjct: 421 IKDCLIGSGQRIEAKAKRVNEVIVGNDQLMEI 452 >5B04-E nrPDB Length = 458 Score = 400 bits (1028), Expect = e-112, Method: Composition-based stats. Identities = 143/458 (31%), Positives = 239/458 (52%), Gaps = 50/458 (10%) Query: 1 MEFQAVVMAVGGGSRMTDLTS--SIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRD 58 +EFQAVV A G G+ + LT ++PK LLP+GNKP++ YPL LE GF I++ + Sbjct: 37 IEFQAVVFA-GFGNSLYPLTGSDALPKALLPIGNKPMLHYPLYWLEAAGFTSAILICMEE 95 Query: 59 VQKALCA------EFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDV 112 + + A E M++ + I DD+ +AD+LR + +K D + LSCD I + Sbjct: 96 AEAHINAWLRSGYEGHMRIHVEAPTILDDSK-SSADALRAVSHLIKNDFVCLSCDSIVGL 154 Query: 113 ALHEVVDLFRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMAN 172 + V+D FR D A+ + E + Q K ++ + IG++ RLL+ + Sbjct: 155 PPYTVLDKFR-LDNPSALAVYSPVLKYEHITSQS---KEIDAKQLIGIEEKTSRLLYAKS 210 Query: 173 EADLDEELVIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYL 232 AD+ + + S+L KHPR+ +T L DAH++ K +++D + E SI+SIR +LIPYL Sbjct: 211 SADVGSDFTFRMSLLWKHPRVTLNTNLSDAHIFVFKHWVIDLIREKESISSIRGDLIPYL 270 Query: 233 VRKQFSSASSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWED 292 V+ Q+ Q+ +E +I F+ N N+ YD Sbjct: 271 VKCQY-----QKSFTVRE-----------NIQRFLSSPN--NIDNYDG-----------G 301 Query: 293 LSRSQVRCYVHIMKEGL-CSRVSTLGLYMEANRQVPKLLSALCPEEPPVHSSAQIVSKHL 351 LS +++ I K+G+ CSR + L Y E N+ + K L PE+ V + + L Sbjct: 302 LSSQEIKINALIAKDGIICSRANNLPNYFELNKCIAK----LTPEQRLVD--VTVSERAL 355 Query: 352 VGVDSLIGPETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEGSNIQGSVICN 411 VG D ++ T I + S+IK+S+IG +C+I V ++N +LM+++ VE+G ++ ++ + Sbjct: 356 VGADCMVNEGTTIKDNSNIKKSIIGKNCVIGKGVVVSNSILMDNIVVEDGVRLESCIVAS 415 Query: 412 NAVIEKGADIKDCLIGSGQRIEAKAKRVNEVIVGNDQL 449 A I + +++C IG R+EA E +V +++ Sbjct: 416 GAQIGAKSKLRECEIGVDHRVEAGRIARGERLVDMEKI 453 >6I7T-I nrPDB Length = 578 Score = 358 bits (917), Expect = 4e-99, Method: Composition-based stats. Identities = 111/490 (22%), Positives = 205/490 (41%), Gaps = 85/490 (17%) Query: 16 MTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRD----VQKALCA------ 65 ++ +PK LLP+GN+P+I Y L+ ++ F+E+ VV D ++ L + Sbjct: 57 FMQHSTRLPKALLPIGNRPMIEYVLDWCDQADFKEISVVAPVDEIELIESGLTSFLSLRK 116 Query: 66 -EFKMKMKP--------------DIVCIPDDADMGTADSL-RYIYPKLKTDVLVLSCDLI 109 +F++ K I IP A+ T +SL + + P++ D ++L CD + Sbjct: 117 QQFELIYKALSNSNHSHHLQDPKKINFIPSKAN-STGESLQKELLPRINGDFVILPCDFV 175 Query: 110 TDVALHEVVDLFRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFI----GVDSTGK 165 TD+ +VD FR D + + ++S++ +K ++K +Q+ F DS + Sbjct: 176 TDIPPQVLVDQFRNRDDNNLAMTIYYKNSLDSSIDKKQQQKQKQQQFFTVYSENEDSERQ 235 Query: 166 RLL---FMANEADLDEELVIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSIT 222 +L + + + L I+ +L +P + T L+++ +Y + L Sbjct: 236 PILLDVYSQRDVTKTKYLQIRSHLLWNYPNLTVSTKLLNSFIYFCSFELCQLL------- 288 Query: 223 SIRSELIPYLVRKQFSSASSQQGQEEKEE---------------DLKKKELKSLDIYSFI 267 +L P + +Q S G ++++ D K S+ ++ Sbjct: 289 ----KLGPQSMSRQASFKDPFTGNQQQQNPPTTDDDEDRNHDDDDDYKPSATSIQP-TYF 343 Query: 268 KEANTLNLAPYDACWNACRGDRWEDLSRSQVRCYVH-----------IMKEGLCSRVSTL 316 K+ N L L P + N + DLSR R + H + E L R + L Sbjct: 344 KKKNDLILDPINC--NKSLSKVFRDLSR---RSWQHSKPREPIGIFILPNETLFIRANNL 398 Query: 317 GLYMEANRQVPKLLSA-LCPEEPPVHSSAQIVSKHLVGVDSLIGPETQIGEKSSIKRSVI 375 YM+ANR V K+ S + + + S+A +G D+++ P+ QI S++K SV+ Sbjct: 399 NAYMDANRFVLKIKSQTMFTKNIQIQSAA-------IGADAIVDPKCQISAHSNVKMSVL 451 Query: 376 GSSCLIKDRVTITNCLLMNSVTVEEGSNIQGSVICNNAVIEKGADIKDCLIGSGQRIEAK 435 G+ I R + LL V + + ++ +I A I + +C I +E K Sbjct: 452 GTQANIGSRCRVAGSLLFPGVHLGDEVILENCIIGPMAKIGSKCKLSNCYIEGHYVVEPK 511 Query: 436 AKRVNEVIVG 445 E + Sbjct: 512 NNFKGETLAN 521 >6I7T-G nrPDB Length = 712 Score = 334 bits (857), Expect = 3e-92, Method: Composition-based stats. Identities = 88/452 (19%), Positives = 174/452 (38%), Gaps = 78/452 (17%) Query: 3 FQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQKA 62 QAVV+ +R LT+ P+ LLP+ N PLI Y L L + G EV ++ + + Sbjct: 27 LQAVVLTDSYETRFMPLTAVKPRCLLPLANVPLIEYTLEFLAKAGVHEVFLICSSHANQ- 85 Query: 63 LCAEFKMKMKPDIVCIPDDAD-------MGTADSLRYIYPK--LKTDVLVLSCDLITDVA 113 ++ K ++ P T D +R + + + D +++S D++T++ Sbjct: 86 -INDYIENSKWNLPWSPFKITTIMSPEARCTGDVMRDLDNRGIITGDFILVSGDVLTNID 144 Query: 114 LHEVVDLFRAYDASLAMLMRKGQDSIEPVPGQKG----KKKAVEQRDFIGVDSTGKRLLF 169 ++++ + + + +D I + K K + +E F+ +D + R ++ Sbjct: 145 FSKMLEFHKK-------MHLQDKDHISTMCLSKASTYPKTRTIEPAAFV-LDKSTSRCIY 196 Query: 170 MAN----EADLDEELVIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIR 225 + + + I +L L+D + ++ EN S+R Sbjct: 197 YQDLPLPSSREKTSIQIDPELLDNVDEFVIRNDLIDCRIDICTSHVPLIFQENFDYQSLR 256 Query: 226 SELIPYLVRKQFSSASSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNL---APYDACW 282 ++ + ++ S G+ IY+++ + + + YD Sbjct: 257 TDFVKGVIS------SDILGKH---------------IYAYLTDEYAVRVESWQTYDTIS 295 Query: 283 NACRGDRWEDLSRSQVRCYVHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPPVHS 342 G RW CY ++ S + Y +R + K Sbjct: 296 QDFLG-RW---------CYPLVLD----SNIQDDQTYSYESRHIYK------------EK 329 Query: 343 SAQIVSKHLVGVDSLIGPETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEGS 402 + +G + IG T+IGE + I+ SVIG +C I + + I N + + + S Sbjct: 330 DVVLAQSCKIGKCTAIGSGTKIGEGTKIENSVIGRNCQIGENIRIKNSFIWDDCIIGNNS 389 Query: 403 NIQGSVICNNAVIEKGADIKD-CLIGSGQRIE 433 I S+I +NA + + D C+IG +I+ Sbjct: 390 IIDHSLIASNATLGSNVRLNDGCIIGFNVKID 421 >6JLY-I nrPDB Length = 678 Score = 320 bits (819), Expect = 1e-87, Method: Composition-based stats. Identities = 87/478 (18%), Positives = 173/478 (36%), Gaps = 107/478 (22%) Query: 2 EFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQK 61 QA+V++ R LT P+ LLP+ N PLI Y L G +EV V Sbjct: 17 ALQAIVLSDSYNYRFRPLTLDKPRCLLPLANTPLIEYTFEFLALAGVQEVYVFCC--AHA 74 Query: 62 ALCAEFKMKMKPDIVCIPDDAD-------MGTADSLRYIYPK--LKTDVLVLSCDLITDV 112 E+ K K ++ P + + D+LR + K + +D +++S D++++V Sbjct: 75 GQIREYIEKSKWNLPSSPFSVNTIVSRESLSVGDALRELDSKQLITSDFILVSGDVVSNV 134 Query: 113 ALHEVVDLFRAY-----DASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRL 167 L+EV+ R +A + M++R E P + + + E F+ T + + Sbjct: 135 PLNEVLKEHRKRREDDKNAIMTMVVR------EASPFHRTRART-ESSVFVIDKKTSQCV 187 Query: 168 LFMANEADLDEELVIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSE 227 + ANE + + I +H + L+D + + EN IR + Sbjct: 188 HYQANERG-KHYVSMDPEIFNEHEELEVRNDLIDCQIDICSNDVPALFTENFDYQDIRKD 246 Query: 228 LIPYLVRKQFSSASSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRG 287 + ++ S G++ K+ + +L YDA Sbjct: 247 FVYGVLT------SDLLGKKIHCHVAKENYAARVR-----------SLQTYDAISKDVLS 289 Query: 288 DRWEDLSRSQVRCYVHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPPVHSS---- 343 + + P+ ++ + Sbjct: 290 ----------------------------------------RWVYPFVPDSNLLNQTFSYQ 309 Query: 344 -AQIVSKH--------LVGVDSLIGPETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMN 394 QI + ++ +LIG T++G+ S + ++IG +C I +I + L Sbjct: 310 RHQIYKEEDVVLARSCIIKARTLIGAYTKVGDASVVANTIIGRNCTIGSNCSIDSAFLWE 369 Query: 395 SVTVEEGSNIQGSVICNNAVIEKGADIKD-CLIGSGQRIEAKAKRVNEVIVGNDQLME 451 V + + I +++ N+ I I+D ++ +G V++G++ ++E Sbjct: 370 DVVIGDNCRIGKAILANSVKIGNNCSIEDGAIVAAG------------VVIGDNTIIE 415 >6O85-A nrPDB Length = 721 Score = 213 bits (542), Expect = 1e-55, Method: Composition-based stats. Identities = 91/471 (19%), Positives = 155/471 (32%), Gaps = 99/471 (21%) Query: 3 FQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQKA 62 QAV++A R ++ P+ LLP+ N LI Y L L G +E V + A Sbjct: 43 LQAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCW--KAA 100 Query: 63 LCAEFKMKMKP-------DIVCIPDDADMGTADSLRYIYPK--LKTDVLVLSCDLITDVA 113 E +K K + I + D LR + K +++D L++ D+I+++ Sbjct: 101 QIKEHLLKSKWCRPTSLNVVRIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISNIN 160 Query: 114 LHEVVDLFRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMANE 173 + ++ R + E P + E + VDST R+L Sbjct: 161 ITRALEEHRLRRKLEKNVSVMTMIFKESSPSH--PTRCHEDNVVVAVDSTTNRVLHFQKT 218 Query: 174 ADLDEELVIKGSILQ-KHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYL 232 L S+ Q + L+D H+ + +N + R + + L Sbjct: 219 QGLRR-FAFPLSLFQGSSDGVEVRYDLLDCHISICSPQVAQLFTDNFDYQT-RDDFVRGL 276 Query: 233 VRKQFSSASSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWED 292 + G + K+ A NL Y A Sbjct: 277 L-----VNEEILGNQIHMHVTAKE-----------YGARVSNLHMYSAVCADV------- 313 Query: 293 LSRSQVRCYVHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPPVHSSAQ--IVSKH 350 + + + L PE S+ Q S+H Sbjct: 314 ---------------------------------IRRWVYPLTPEANFTDSTTQSCTHSRH 340 Query: 351 --------------LVGVDSLIGPETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSV 396 ++ + L+G T IG I SVIG C I D V + L V Sbjct: 341 NIYRGPEVSLGHGSILEENVLLGSGTVIGSNCFITNSVIGPGCHIGDNVVLDQTYLWQGV 400 Query: 397 TVEEGSNIQGSVICNNAVIEKGADIKDCLIGSGQRIEAKAKRVNEVIVGND 447 V G+ I S++C+NA +++ +K ++ ++V+VG + Sbjct: 401 RVAAGAQIHQSLLCDNAEVKERVTLK-----------PRSVLTSQVVVGPN 440 >4JD0-A nrPDB Length = 251 Score = 108 bits (269), Expect = 5e-24, Method: Composition-based stats. Identities = 34/148 (22%), Positives = 65/148 (43%), Gaps = 9/148 (6%) Query: 3 FQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTT---RDV 59 +A+V+A G G R+ +T +PK L+ YP+ L + G E ++V + RD+ Sbjct: 12 REAIVLASGAGKRLRSVTGDVPKVFYRFDGCELVKYPMISLMKNGVERFVLVVSEGYRDL 71 Query: 60 QKALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSC-DLITDVALHEVV 118 + + + ++ IV ++G A S P ++++ LSC D + + Sbjct: 72 GEKVLNDLGVE---GIVVENKKVELGNAYSFFLSEPYVESEKFFLSCGDSL--FPPSALK 126 Query: 119 DLFRAYDASLAMLMRKGQDSIEPVPGQK 146 F + + + + K D I+P K Sbjct: 127 SAFSEDEFHIKLGVSKRSDLIDPEKASK 154 >5Z09-A nrPDB Length = 409 Score = 107 bits (267), Expect = 9e-24, Method: Composition-based stats. Identities = 27/107 (25%), Positives = 54/107 (50%), Gaps = 6/107 (5%) Query: 3 FQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQKA 62 +A ++A G G R+ +T + PK +P+ +KPLI Y + L + G ++ V+ + ++ Sbjct: 1 MKAFILAAGSGERLEPITHTRPKAFVPILSKPLIEYQIEYLRKCGIRDITVIVSSKNKEY 60 Query: 63 LCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLI 109 F+ K+K + D GT ++ + K + L+++ DL Sbjct: 61 ----FEKKLKEISIVTQKDDIKGTGAAI--LSAKFNDEALIINGDLF 101 Score = 29.0 bits (63), Expect = 4.5, Method: Composition-based stats. Identities = 35/223 (15%), Positives = 69/223 (30%), Gaps = 19/223 (8%) Query: 237 FSSASSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWEDLSRS 296 + S +K ++ EL+ D + + + + + + Y+ W G W + + Sbjct: 161 YKLNSDIFTYLDKISISERGELELTDAINLMAKDHRVKVIEYEGYWMD-IGKPWNIIDVN 219 Query: 297 QVRCYVHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPPVHSSAQIVSKHLVGVDS 356 + + + L + ++ +V A + I +G +S Sbjct: 220 KWALDNLVFSQNLG----NVEDNVKIKGKVIIEEDAEIKSGTYIEGPVYIGKGSEIGPNS 275 Query: 357 LIGPET------QIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEGSNIQG---- 406 + P T +IG +K SVI I + + ++ V G+ I Sbjct: 276 YLRPYTILVEKNKIGASVEVKESVIMEGSKIPHLSYVGDSVIAEDVNFGAGTLIANLRFD 335 Query: 407 ----SVICNNAVIEKGADIKDCLIGSGQRIEAKAKRVNEVIVG 445 V I G IG R + V +G Sbjct: 336 EKEVKVNVKGKRISSGRRKLGAFIGGHVRTGINVTILPGVKIG 378 >3ZLK-A nrPDB Length = 303 Score = 99.5 bits (246), Expect = 2e-21, Method: Composition-based stats. Identities = 34/132 (25%), Positives = 60/132 (45%), Gaps = 24/132 (18%) Query: 1 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRD-- 58 M+ + +++A G G+R+ T +I K LLPV +KP+I+YPL+ L G E+++++T Sbjct: 11 MKRKGIILAGGSGTRLHPATLAISKQLLPVYDKPMIYYPLSTLMLAGIREILIISTPQDT 70 Query: 59 ----------VQKALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTD--VLVLSC 106 L ++ ++ PD G A + + D LVL Sbjct: 71 PRFQQLLGDGSNWGLDLQYAVQPSPD----------GLAQAFLIGESFIGNDLSALVLGD 120 Query: 107 DLITDVALHEVV 118 +L HE++ Sbjct: 121 NLYYGHDFHELL 132 >6N0U-A nrPDB Length = 305 Score = 99.2 bits (245), Expect = 3e-21, Method: Composition-based stats. Identities = 32/151 (21%), Positives = 63/151 (41%), Gaps = 24/151 (15%) Query: 1 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRD-- 58 M + +++A G G+R+ +T + K LLPV +KP+I+YPL+ L G +V++++T Sbjct: 9 MARKGIILAGGSGTRLYPITHVVSKQLLPVYDKPMIYYPLSTLMVAGIRDVLIISTPQDT 68 Query: 59 ----------VQKALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTD--VLVLSC 106 Q + ++ ++ PD G A + + D L+L Sbjct: 69 PRFEAMLGDGSQWGMNIQYAVQPSPD----------GLAQAFIIGREFVGNDPSALILGD 118 Query: 107 DLITDVALHEVVDLFRAYDASLAMLMRKGQD 137 ++ L + ++ A + D Sbjct: 119 NIFYGHDLAKQLERANARTDGATVFAYHVHD 149 >1H5S-D nrPDB Length = 293 Score = 98.8 bits (244), Expect = 4e-21, Method: Composition-based stats. Identities = 23/84 (27%), Positives = 47/84 (55%), Gaps = 12/84 (14%) Query: 3 FQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRD---- 58 + +++A G G+R+ +T ++ K LLP+ +KP+I+YPL+ L G ++++++T Sbjct: 4 RKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPR 63 Query: 59 --------VQKALCAEFKMKMKPD 74 Q L ++K++ PD Sbjct: 64 FQQLLGDGSQWGLNLQYKVQPSPD 87 >5IFY-A nrPDB Length = 305 Score = 98.8 bits (244), Expect = 5e-21, Method: Composition-based stats. Identities = 33/151 (21%), Positives = 65/151 (43%), Gaps = 24/151 (15%) Query: 1 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRD-- 58 M + +++A G G+R+ +T ++ K LLPV +KP+I+YPL+ L G +V++++T Sbjct: 9 MARKGIILAGGSGTRLYPITHAVSKQLLPVYDKPMIYYPLSTLMIAGIRDVLIISTPQDT 68 Query: 59 ----------VQKALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTD--VLVLSC 106 Q + ++ + PD G A + + + L+L Sbjct: 69 PRFESMLGDGSQWGMNIQYATQPSPD----------GLAQAFVIGRDFVGNEPSALILGD 118 Query: 107 DLITDVALHEVVDLFRAYDASLAMLMRKGQD 137 ++ L + ++ A D + QD Sbjct: 119 NIFYGHDLAKQLERASAKDTGATVFAYHVQD 149 >3PKP-A nrPDB Length = 292 Score = 98.0 bits (242), Expect = 8e-21, Method: Composition-based stats. Identities = 23/84 (27%), Positives = 46/84 (54%), Gaps = 12/84 (14%) Query: 3 FQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRD---- 58 + +++A G G+R+ +T ++ K LLP+ +KP+I+YPL+ L G ++++++T Sbjct: 4 RKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPR 63 Query: 59 --------VQKALCAEFKMKMKPD 74 Q L ++K+ PD Sbjct: 64 FQQLLGDGSQWGLNLQYKVSPSPD 87 >1WVC-A nrPDB Length = 259 Score = 93.8 bits (231), Expect = 1e-19, Method: Composition-based stats. Identities = 30/179 (16%), Positives = 71/179 (39%), Gaps = 24/179 (13%) Query: 1 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRD-- 58 M +AV++A G G+R+++ T PKP++ +G KP++W+ + + G ++ I+ Sbjct: 1 MASKAVILAGGLGTRLSEETIVKPKPMVEIGGKPILWHIMKMYSVHGIKDFIICCGYKGY 60 Query: 59 -VQKALCAEF-------------------KMKMKPDIVCIPDDADMGTADSLRYIYPKLK 98 +++ F K ++ + T L+ + +K Sbjct: 61 VIKEYFANYFLHMSDVTFHMAENRMEVHHKRVEPWNVTLVDTGDSSMTGGRLKRVAEYVK 120 Query: 99 TD--VLVLSCDLITDVALHEVVDLFRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQR 155 D L D + D+ + +D +A+ + + Q G+ ++ +++ Sbjct: 121 DDEAFLFTYGDGVADLDIKATIDFHKAHGKKATLTATFPPGRFGALDIQAGQVRSFQEK 179 >5IDS-A nrPDB Length = 302 Score = 93.4 bits (230), Expect = 2e-19, Method: Composition-based stats. Identities = 25/85 (29%), Positives = 46/85 (54%), Gaps = 12/85 (14%) Query: 2 EFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRD--- 58 + + +++A G G+R+ T +I K LLPV +KP+I+YPL+ L G +V+V++T Sbjct: 11 QRKGIILAGGSGTRLHPATLAISKQLLPVYDKPMIYYPLSTLMLAGMRDVLVISTPQDTP 70 Query: 59 ---------VQKALCAEFKMKMKPD 74 Q + ++ ++ PD Sbjct: 71 RFQQLLGDGSQWGMNLQYAVQPSPD 95 >1LVW-A nrPDB Length = 295 Score = 93.0 bits (229), Expect = 2e-19, Method: Composition-based stats. Identities = 30/143 (20%), Positives = 66/143 (46%), Gaps = 12/143 (8%) Query: 3 FQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVV-TTRDVQ- 60 + +V+A G G+R+ +T ++ K LLP+ +KP+I+YPL++L G +++++ T RD+ Sbjct: 4 MKGIVLAGGSGTRLYPITRAVSKQLLPIYDKPMIYYPLSVLMLAGIRDILIISTPRDLPL 63 Query: 61 ----KALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVL--VLSCDLITDVAL 114 ++F ++ + P G AD+ + + VL ++ Sbjct: 64 YRDLLGDGSQFGVRFSYRVQEEPR----GIADAFIVGKDFIGDSKVALVLGDNVFYGHRF 119 Query: 115 HEVVDLFRAYDASLAMLMRKGQD 137 E++ + + + +D Sbjct: 120 SEILRRAASLEDGAVIFGYYVRD 142 >1MC3-A nrPDB Length = 296 Score = 91.1 bits (224), Expect = 9e-19, Method: Composition-based stats. Identities = 28/108 (25%), Positives = 55/108 (50%), Gaps = 10/108 (9%) Query: 3 FQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQKA 62 + +++A G G+R+ +T + K LLP+ +KP+I+YPL++L G E++++TT + + Sbjct: 4 MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGY 63 Query: 63 LC------AEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVL 104 +EF ++++ PD G A + L + L Sbjct: 64 FQRLLGDGSEFGIQLEYAEQPSPD----GLAQAFIIGETFLNGEPSCL 107 >4HO3-A nrPDB Length = 297 Score = 91.1 bits (224), Expect = 1e-18, Method: Composition-based stats. Identities = 29/143 (20%), Positives = 64/143 (44%), Gaps = 12/143 (8%) Query: 3 FQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQK- 61 + ++++ G G+R+ LT + K LLPV +KP+++YPL++L G +++++++T + Sbjct: 1 MKGIILSGGSGTRLYPLTKVVSKQLLPVYDKPMVYYPLSVLMLAGIKDILIISTPEDTPR 60 Query: 62 -----ALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTD--VLVLSCDLITDVAL 114 +E + + + PD G A + + D LVL ++ Sbjct: 61 FEQLLGGGSELGISLSYAVQSSPD----GLAQAFIIGEEFIGDDNVALVLGDNIFYGHGF 116 Query: 115 HEVVDLFRAYDASLAMLMRKGQD 137 E++ + + +D Sbjct: 117 TELLQRAANRKSGATIFGYNVKD 139 >6B5K-A nrPDB Length = 296 Score = 89.1 bits (219), Expect = 4e-18, Method: Composition-based stats. Identities = 30/125 (24%), Positives = 52/125 (41%), Gaps = 4/125 (3%) Query: 3 FQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQKA 62 + +++A G G+R+ +T I K LLPV +KP+I+YPL L G ++ ++TT Sbjct: 1 MRGIILAGGSGTRLYPITMGISKQLLPVYDKPMIYYPLTTLMMAGIRDIQLITTPHDAPG 60 Query: 63 LCAEFKMKMKPDIVCI--PDDADMGTADSLRYIYPKLKTD--VLVLSCDLITDVALHEVV 118 + D G A + + D LVL ++ L + Sbjct: 61 FHRLLGDGAHLGVNISYATQDQPDGLAQAFVIGANHIGADSVALVLGDNIFYGPGLGTSL 120 Query: 119 DLFRA 123 F++ Sbjct: 121 KRFQS 125 >5I1F-A nrPDB Length = 302 Score = 86.1 bits (211), Expect = 3e-17, Method: Composition-based stats. Identities = 34/173 (19%), Positives = 59/173 (34%), Gaps = 12/173 (6%) Query: 4 QAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTR------ 57 +AV G G+R T + PK +LPV +KPLI Y + G E+I VT R Sbjct: 14 KAVFPVAGLGTRFLPATKASPKEMLPVVDKPLIQYAVEEAIEAGITEMIFVTGRSKRAIE 73 Query: 58 ---DVQKALCAEFKMKMKPDIVCIPDDADMGTADSL--RYIYPKLKTDVLVLSCDLITDV 112 D + AE + + K ++ + D R ++ + L+ D Sbjct: 74 DHFDKSYEIEAELEARGKEKLLSLVRSIKPSHVDCFYVRQAEALGLGHAVLCAEKLVGDN 133 Query: 113 ALHEVV-DLFRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTG 164 ++ D + M D + + + + +D Sbjct: 134 PFAVILADDLLDGPTPVLRQMIDVFDHYHASVIGVEEIAPADSKSYGVIDGKR 186 >4Y7U-A nrPDB Length = 231 Score = 85.7 bits (210), Expect = 4e-17, Method: Composition-based stats. Identities = 33/119 (27%), Positives = 53/119 (44%), Gaps = 6/119 (5%) Query: 3 FQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIV---VTTRDV 59 +A+++A G G RM LT PKPL+PV +PLI Y L L G EV++ + + Sbjct: 1 MKAMILAAGKGERMRPLTLHTPKPLVPVAGQPLIEYHLRALAAAGVTEVVINHAWLGQQI 60 Query: 60 QKALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKT-DVLVLSCDLITDVALHEV 117 + L + I P+ + T + P L L+++ D+ TD + Sbjct: 61 EDHLGD--GSRFGLSIRYSPEGEPLETGGGIFKALPLLGDAPFLLVNGDVWTDYDFARL 117 >5J49-A nrPDB Length = 301 Score = 84.9 bits (208), Expect = 6e-17, Method: Composition-based stats. Identities = 37/172 (21%), Positives = 61/172 (35%), Gaps = 12/172 (6%) Query: 4 QAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTR------ 57 +AV G G+R T + PK +LP+ +KPLI Y + G E+I VT R Sbjct: 14 KAVFPVAGLGTRFLPATKASPKEMLPIVDKPLIQYAVEEAMAAGITEMIFVTGRSKRAIE 73 Query: 58 ---DVQKALCAEFKMKMKPDIVCIPDDADMGTADSL--RYIYPKLKTDVLVLSCDLITDV 112 D + AE + + K ++ + D R ++ + L+ D Sbjct: 74 DHFDKSYEIEAELQARGKDKLLELVRSIKPSHVDCFYVRQPEALGLGHAVLCAEKLVGDN 133 Query: 113 ALHEVVDLFRAYDASLAML-MRKGQDSIEPVPGQKGKKKAVEQRDFIGVDST 163 ++ Y M M + D + A E + + VD Sbjct: 134 PFAVILADDLLYGTPPVMAQMIEVFDHYHSSVIGVEEIPAQETKSYGIVDGK 185 >5VE7-A nrPDB Length = 302 Score = 84.5 bits (207), Expect = 1e-16, Method: Composition-based stats. Identities = 36/172 (20%), Positives = 60/172 (34%), Gaps = 12/172 (6%) Query: 4 QAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTR------ 57 +AV G G+R T + PK +LPV +KPLI Y + G E+I VT R Sbjct: 14 KAVFPVAGLGTRFLPATKASPKEMLPVVDKPLIQYAVEEAIAAGITEMIFVTGRSKRAIE 73 Query: 58 ---DVQKALCAEFKMKMKPDIVCIPDDADMGTADSL--RYIYPKLKTDVLVLSCDLITDV 112 D + AE + + K ++ + D R ++ + L+ D Sbjct: 74 DHFDKSYEVEAELEARGKAKLLELVRSIKPSHVDCFYVRQPEALGLGHAVLCAEKLVADN 133 Query: 113 ALHEVV-DLFRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDST 163 ++ D + + M D + E + + VD Sbjct: 134 PFAVILADDLLDGNPPVMKQMVDVFDHYHSSVIGVEEIPPSETKSYGIVDGK 185 >2UX8-A nrPDB Length = 297 Score = 83.7 bits (205), Expect = 2e-16, Method: Composition-based stats. Identities = 27/125 (21%), Positives = 51/125 (40%), Gaps = 9/125 (7%) Query: 3 FQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRD---V 59 +AV G G+R T ++PK +LPV ++PLI Y ++ G E++I VT R + Sbjct: 15 RKAVFPVAGLGTRFLPATKAMPKEMLPVVDRPLIQYAVDEAVEAGIEQMIFVTGRGKSAL 74 Query: 60 QKALCAEFKMKMKPDIVCIPDDA------DMGTADSLRYIYPKLKTDVLVLSCDLITDVA 113 + ++++ D G +R P + + D++ D Sbjct: 75 EDHFDIAYELEATMAARGKSLDVLDGTRLKPGNIAYVRQQEPMGLGHAVWCARDIVGDEP 134 Query: 114 LHEVV 118 ++ Sbjct: 135 FAVLL 139 >1JYL-A nrPDB Length = 254 Score = 83.4 bits (204), Expect = 2e-16, Method: Composition-based stats. Identities = 27/103 (26%), Positives = 49/103 (47%), Gaps = 2/103 (1%) Query: 1 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQ 60 + +A+++A G G+R+ LT + PK L+ V KPLI Y + L+ G ++I++ + Sbjct: 24 IRVKAIILAAGLGTRLRPLTENTPKALVQVNQKPLIEYQIEFLKEKGINDIIIIVGYLKE 83 Query: 61 KALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLV 103 + K K +V AD SL + +L ++ Sbjct: 84 QFDY--LKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVI 124 >5XHW-A nrPDB Length = 237 Score = 83.0 bits (203), Expect = 2e-16, Method: Composition-based stats. Identities = 21/119 (17%), Positives = 58/119 (48%), Gaps = 2/119 (1%) Query: 3 FQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQKA 62 + V++A G G+R+ ++ IPKP++ + KP ++ + LE G + +I+ + Sbjct: 14 YDVVILAGGLGTRLKSVSGDIPKPMVDISGKPFLYRLMEYLEDQGVQRIILSLSYKADYI 73 Query: 63 LCAEFKMKM-KPDIVCIPDDADMGTADSLRYIYPKLK-TDVLVLSCDLITDVALHEVVD 119 + + K + I ++ +GT +++ ++ + +V++ D ++ + ++ Sbjct: 74 IDSLIKDNPVNSKVDFIIENEPLGTGGAIKNACKYIEASKFIVINGDTYCELDYKKFIE 132 >4D48-A nrPDB Length = 302 Score = 79.9 bits (195), Expect = 2e-15, Method: Composition-based stats. Identities = 22/61 (36%), Positives = 33/61 (54%) Query: 4 QAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQKAL 63 +AV+ G G+RM T +IPK +LP+ +KPLI Y +N G E+++VT Sbjct: 10 KAVIPVAGLGTRMLPATKAIPKEMLPLVDKPLIQYVVNECIAAGINEIVLVTHSSKNSIE 69 Query: 64 C 64 Sbjct: 70 N 70 >2E3D-A nrPDB Length = 302 Score = 79.5 bits (194), Expect = 3e-15, Method: Composition-based stats. Identities = 22/61 (36%), Positives = 33/61 (54%) Query: 4 QAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQKAL 63 +AV+ G G+RM T +IPK +LP+ +KPLI Y +N G E+++VT Sbjct: 10 KAVIPVAGLGTRMLPATKAIPKEMLPLVDKPLIQYVVNECIAAGITEIVLVTHSSKNSIE 69 Query: 64 C 64 Sbjct: 70 N 70 >3JUK-A nrPDB Length = 281 Score = 79.1 bits (193), Expect = 4e-15, Method: Composition-based stats. Identities = 21/73 (28%), Positives = 39/73 (53%), Gaps = 3/73 (4%) Query: 1 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRD-- 58 M + + A G G+R +T +IPK +LP+ +KPLI Y + G E + +VT R+ Sbjct: 1 MIKKCLFPAAGYGTRFLPITKTIPKEMLPIVDKPLIQYAVEEAMEAGCEVMAIVTGRNKR 60 Query: 59 -VQKALCAEFKMK 70 ++ ++++ Sbjct: 61 SLEDYFDTSYEIE 73 >4ECM-A nrPDB Length = 269 Score = 71.8 bits (174), Expect = 5e-13, Method: Composition-based stats. Identities = 30/155 (19%), Positives = 65/155 (41%), Gaps = 3/155 (1%) Query: 2 EFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQK 61 + +++A G GSR+ +T K LLPVG P+I++ + L++ +++++T ++ Sbjct: 24 AMKGIILAGGTGSRLYPITKVTNKHLLPVGRYPMIYHAVYKLKQCDITDIMIITGKEHMG 83 Query: 62 ALCAEFKMKMKPDIVCI--PDDADMGTADSLRYIYPKLKTD-VLVLSCDLITDVALHEVV 118 + + + + D G A +L + D ++V+ D I + V Sbjct: 84 DVVSFLGSGQEFGVSFTYRVQDKAGGIAQALGLCEDFVGNDRMVVILGDNIFSDDIRPYV 143 Query: 119 DLFRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVE 153 + F +L++ D +K +E Sbjct: 144 EEFTNQKEGAKVLLQSVDDPERFGVANIQNRKIIE 178 >2V0L-A nrPDB Length = 456 Score = 69.9 bits (169), Expect = 2e-12, Method: Composition-based stats. Identities = 80/461 (17%), Positives = 156/461 (33%), Gaps = 79/461 (17%) Query: 2 EFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQK 61 AV++A G G+RM +PK L + KP++ + ++ ++G E + ++ Sbjct: 5 ALSAVILAAGKGTRMYS---DLPKVLHTIAGKPMVKHVIDTAHQLGSENIHLIYGHGGDL 61 Query: 62 ALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKT--DVLVLSCD--LITDVALHEV 117 ++ + +GTA +++ P K +++VL D LIT L ++ Sbjct: 62 MRTHLANEQVNWVLQTEQ----LGTAHAVQQAAPFFKDNENIVVLYGDAPLITKETLEKL 117 Query: 118 VDLFRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMANEADLD 177 ++ + +A+L +++ G + I Sbjct: 118 IEA--KPENGIALLTV----NLDNPTGYGRIIRENGNVVAIVEQKDAN-----------A 160 Query: 178 EELVIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYLVRKQF 237 E+L IK +TG++ + KK++ N ++LI L + Sbjct: 161 EQLNIK----------EVNTGVMVSDGASFKKWLARVGNNNAQGEYYLTDLI-ALANQDN 209 Query: 238 SSASSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNL-----APYDACWNACRGDRWED 292 + Q + E + L+ + + + L YD RG Sbjct: 210 CQVVAVQATDVMEVEGANNRLQLAALERYFQNKQASKLLLEGVMIYDPARFDLRGTLEH- 268 Query: 293 LSRSQVRCYVHIMKEG---LCSRVS----------------TLGLYMEANRQVPKLLSAL 333 V V+++ EG L RV + Y + +A+ Sbjct: 269 --GKDVEIDVNVIIEGNVKLGDRVKIGTGCVLKNVVIGNDVEIKPYSVLEDSIVGEKAAI 326 Query: 334 CPEEPP---VHSSAQIVSKHLVG-VDSLIGPETQIGEKSSIKRSVIGSSCLIKDRVTITN 389 P +A+ + V S +G +++ + + S IGS+C I V N Sbjct: 327 GPFSRLRPGAELAAETHVGNFVEIKKSTVGKGSKVNHLTYVGDSEIGSNCNIGAGVITCN 386 Query: 390 --------CLLMNSVTVEEGSNIQGSV-ICNNAVIEKGADI 421 ++ + V V + + V + N A I G I Sbjct: 387 YDGANKFKTIIGDDVFVGSDTQLVAPVKVANGATIGAGTTI 427 Score = 41.8 bits (96), Expect = 7e-04, Method: Composition-based stats. Identities = 18/107 (16%), Positives = 44/107 (41%), Gaps = 2/107 (1%) Query: 342 SSAQIVSKHLVGVDSLIGPETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEG 401 +I ++ + +G +IG +K VIG+ IK + + ++ + Sbjct: 270 KDVEIDVNVIIEGNVKLGDRVKIGTGCVLKNVVIGNDVEIKPYSVLEDSIVGEKAAIGPF 329 Query: 402 SNIQ-GSVICNNAVIEKGADIKDCLIGSGQRIEAKAKRVNEVIVGND 447 S ++ G+ + + +IK +G G ++ V + +G++ Sbjct: 330 SRLRPGAELAAETHVGNFVEIKKSTVGKGSKVN-HLTYVGDSEIGSN 375 >1YP3-A nrPDB Length = 451 Score = 68.7 bits (166), Expect = 5e-12, Method: Composition-based stats. Identities = 78/479 (16%), Positives = 157/479 (32%), Gaps = 107/479 (22%) Query: 14 SRMTDLTSSIPKPLLPVG-NKPLIWYPLNLLERVGFEEVIVVT---------------TR 57 +R+ LT KP +P+G N LI P++ ++ V+T Sbjct: 32 TRLYPLTKKRAKPAVPLGANYRLIDIPVSNCLNSNISKIYVLTQFNSASLNRHLSRAYAS 91 Query: 58 DVQKALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKT----DVLVLSCDLITDVA 113 ++ F + D GTAD++R + + L+L+ D + + Sbjct: 92 NMGGYKNEGFVEVLAAQQSPENPDWFQGTADAVRQYLWLFEEHTVLEYLILAGDHLYRMD 151 Query: 114 LHEVVDLFRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMANE 173 + + R DA + + + G + +D G+ + F Sbjct: 152 YEKFIQAHRETDADITVAALPMDEKRATAFG------------LMKIDEEGRIIEFAEKP 199 Query: 174 ADLD-EELVIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYL 232 + + + +IL GL D K + + + I I +++ L Sbjct: 200 QGEQLQAMKVDTTIL----------GLDDKR----AKEMP--FIASMGIYVISKDVMLNL 243 Query: 233 VRKQFSSASSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWED 292 +R +F A+ E + + + +++ + ++ +A +NA G + Sbjct: 244 LRDKFPGANDFGS-----EVIPGATSLGMRVQAYLYDGYWEDIGTIEAFYNANLGITKKP 298 Query: 293 LSRSQVRCYVHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPPVHSSAQIVSKHLV 352 + R + +Y + P+ L P + + Sbjct: 299 -----------VPDFSFYDR--SAPIYTQ-----PRYL----PPSKMLDADVT------- 329 Query: 353 GVDSLIGPETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNS----------------- 395 DS+IG I I SV+G I + I + LLM + Sbjct: 330 --DSVIGEGCVIK-NCKIHHSVVGLRSCISEGAIIEDSLLMGADYYETDADRKLLAAKGS 386 Query: 396 --VTVEEGSNIQGSVICNNAVIEKGADI--KDCLIGSGQRIEAKAKRVNEVIVGNDQLM 450 + + + +I+ ++I NA I I KD + + + + + V V D L+ Sbjct: 387 VPIGIGKNCHIKRAIIDKNARIGDNVKIINKDNVQEAARETDGYFIKSGIVTVIKDALI 445 >3FWW-A nrPDB Length = 456 Score = 68.3 bits (165), Expect = 6e-12, Method: Composition-based stats. Identities = 74/436 (16%), Positives = 141/436 (32%), Gaps = 35/436 (8%) Query: 5 AVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQKALC 64 V++A G G+RM +PK L P+ KP++ + ++ ++G + V +V Sbjct: 8 VVILAAGKGTRMYS---DLPKVLHPLAGKPMVQHVIDAAMKLGAQHVHLVYG---HGGEL 61 Query: 65 AEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEVVDLFRAY 124 + K P + + +GT +++ P D +L L DV L V L R Sbjct: 62 LK-KTLADPSLNWVLQAEQLGTGHAMQQAAPHFADDEDILM--LYGDVPLISVDTLQRLL 118 Query: 125 DASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMANEADLDEELVIKG 184 A + ++ G + I NE + Sbjct: 119 AAKPEGGIGLLTVKLDNPSGYGRIVRENGDVVGIVEHKDASDAQREINEINTGI------ 172 Query: 185 SILQKHPRIRFHTGLVDAHLYCLKKYIVDFL-------MENGSITSIRSELIPYLVRKQF 237 ++ ++ L+D + + YI D + + ++ R + + + Sbjct: 173 -LVANGRDLKRWLSLLDNNNAQGEFYITDIIALAHADGKKIATVHPTRLSEVEGVNNRLQ 231 Query: 238 SSASSQQGQEEKEEDLKKKELKSLDIYSF-IKEANTLNLA-PYDACWNACRGDRWEDLSR 295 SA + Q E+ E L + LD F ++ T D D R Sbjct: 232 LSALERVFQTEQAEKLLLAGVMLLDPSRFDLRGELTHGRDITIDTNVIIEGHVILGDRVR 291 Query: 296 SQVRCYVHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPPVHSSAQIVSKHLVG-V 354 C + G S +S + +A + P + + V Sbjct: 292 IGTGCVLKNCVIGDDSEISPYTVLEDARLDANCTVGPFARLRPGAELAEGAHVGNFVEIK 351 Query: 355 DSLIGPETQIGEKSSIKRSVIGSSCLIKDRVTITN--------CLLMNSVTVEEGSNIQG 406 + +G ++ G S + + IG+ I N ++ + V V + + Sbjct: 352 KARLGKGSKAGHLSYLGDAEIGAGVNIGAGTITCNYDGANKFKTIIGDDVFVGSDTQLVA 411 Query: 407 SV-ICNNAVIEKGADI 421 V + N A I G + Sbjct: 412 PVTVANGATIGAGTTV 427 Score = 46.8 bits (109), Expect = 2e-05, Method: Composition-based stats. Identities = 22/133 (16%), Positives = 44/133 (33%), Gaps = 25/133 (18%) Query: 343 SAQIVSKHLVGVDSLIGPETQIGEKSSIKRSVIG-----------------SSCLIKDRV 385 I + ++ ++G +IG +K VIG ++C + Sbjct: 271 DITIDTNVIIEGHVILGDRVRIGTGCVLKNCVIGDDSEISPYTVLEDARLDANCTVGPFA 330 Query: 386 TIT-NCLLMNSVTVEEGSNIQGSVICNNAVIEKGADIKDCLIGSGQRIEAKAKRVN---- 440 + L V I+ + + + + + D IG+G I A N Sbjct: 331 RLRPGAELAEGAHVGNFVEIKKARLGKGSKAGHLSYLGDAEIGAGVNIGAGTITCNYDGA 390 Query: 441 ---EVIVGNDQLM 450 + I+G+D + Sbjct: 391 NKFKTIIGDDVFV 403 >5MNI-E nrPDB Length = 431 Score = 67.2 bits (162), Expect = 1e-11, Method: Composition-based stats. Identities = 82/455 (18%), Positives = 144/455 (31%), Gaps = 75/455 (16%) Query: 1 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNK-PLIWYPLNLLERVGFEEVIVVTTRDV 59 ++ A+++A G G+R+ DLT+ KP + G K +I + L+ G + V+T Sbjct: 18 LKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCINSGIRRMGVITQYQS 77 Query: 60 QKAL------CAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVA 113 + + F +M + +P M + R D + + D+I Sbjct: 78 HTLVQHIQRGWSFFNEEMNEFVDLLPAQQRMKGENWYRG-----TADAVTQNLDIIRAYK 132 Query: 114 LHEVVDLFRAYDASLAMLMRKGQDSIEPVPGQKGK-KKAVEQRDFIGVDSTGKRLLFMAN 172 VV LA QD + K + + ++ + + Sbjct: 133 AEYVV--------ILAGDHIYKQDYSRMLIDHVEKGARCTVACMPVPIEEASAFGVMAVD 184 Query: 173 EADLDEELVIKGSILQKHPRIRFHTGLVDAHLYCL-KKYIVDFLMENG----SITSIRSE 227 E D E V K + P L +Y Y+ + L E+ S + Sbjct: 185 ENDKIIEFVEKPANPPSMPN-DPSKSLASMGIYVFDADYLYELLEEDDRDENSSHDFGKD 243 Query: 228 LIPYLVRKQFSSASSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRG 287 LIP + + A + + E ++ +A W A Sbjct: 244 LIPKITEAGLAYAHPFPLSCVQSDPD--------------AEPYWRDVGTLEAYWKANL- 288 Query: 288 DRWEDLSRSQVRCYVHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPPVHSSAQIV 347 L S V L +Y E P Q Sbjct: 289 --------------------DLASVVPELDMYD------RNWPIRTYNESLPPAKFVQDR 322 Query: 348 S-KHLVGVDSLIGPETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEGSNIQG 406 S H + ++SL+ I S + +SV+ S + I + +L+ V V ++ Sbjct: 323 SGSHGMTLNSLVSGGCVI-SGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRR 381 Query: 407 SVICNNAVIEKGADIKDCLIGSGQRIEAKAKRVNE 441 VI VI +G +IG +A+ +E Sbjct: 382 CVIDRACVIPEGM-----VIGENAEEDARRFYRSE 411 >2OI7-A nrPDB Length = 456 Score = 67.2 bits (162), Expect = 1e-11, Method: Composition-based stats. Identities = 64/458 (13%), Positives = 148/458 (32%), Gaps = 68/458 (14%) Query: 2 EFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQK 61 V++A G G+RM +PK L + K ++ + ++ +G V +V Sbjct: 5 AMSVVILAAGKGTRMYS---DLPKVLHTLAGKAMVQHVIDAANELGAAHVHLVYG---HG 58 Query: 62 ALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEVVDLF 121 + +K ++ + +GT +++ P D +L L DV L V L Sbjct: 59 GDLLKQALK-DDNLNWVLQAEQLGTGHAMQQAAPFFADDEDILM--LYGDVPLISVETLQ 115 Query: 122 RAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMANEADLDEELV 181 R DA + ++ G + + ++ + D ++ Sbjct: 116 RLRDAKPQGGIGLLTVKLDDPTGYGRITRE---------NGKVTGIVEHKDATDEQRQIQ 166 Query: 182 IKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYLVRKQFSSAS 241 +TG++ A+ +K+++ N +++I Sbjct: 167 ------------EINTGILIANGADMKRWLAKLTNNNAQGEYYITDII------------ 202 Query: 242 SQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWEDLSRSQVRCY 301 + I + L+ + N + R E + +S+ Sbjct: 203 ----------------ALAYQEGREIVAVHPQRLSEVEGVNNRLQLSRLERVYQSEQAEK 246 Query: 302 VHIMKEGLCSRVS-TLGLYMEANRQVPKLLSALCPEEPPVHSSAQIVSKHLVGVDSLIGP 360 + + L L + R V + + + +I + ++ +S+IG Sbjct: 247 LLLAGVMLRDPARFDLRGTLTHGRDVEIDTNVIIEGNVTLGHRVKIGTGCVI-KNSVIGD 305 Query: 361 ETQIGEKSSIKRSVIGSSCLIKDRVTIT-NCLLMNSVTVEEGSNIQGSVICNNAVIEKGA 419 + +I + ++ + + ++C I + L+ V ++ + + + Sbjct: 306 DCEISPYTVVEDANLAAACTIGPFARLRPGAELLEGAHVGNFVEMKKARLGKGSKAGHLT 365 Query: 420 DIKDCLIGSGQRIEAKAKRVN-------EVIVGNDQLM 450 + D IG I A N + I+G+D + Sbjct: 366 YLGDAEIGDNVNIGAGTITCNYDGANKFKTIIGDDVFV 403 >5VMK-A nrPDB Length = 462 Score = 65.6 bits (158), Expect = 4e-11, Method: Composition-based stats. Identities = 67/441 (15%), Positives = 159/441 (36%), Gaps = 55/441 (12%) Query: 1 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQ 60 M +++A G G+RM +PK L P+ +PL+ + + +++ E +I + Sbjct: 9 MSTTVIILAAGKGTRMRS---QLPKVLQPLAGRPLLGHVIKTAKQLLAENIITIYG-HGG 64 Query: 61 KALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTD--VLVLSCD--LITDVALHE 116 + F + +I + +GT +++ P L D L+L D L+ L + Sbjct: 65 DHVKKTF---AQENIQWVEQAEQLGTGHAVQMTLPVLPKDGISLILYGDVPLVRQTTLEQ 121 Query: 117 VVDLFRAYDASLAMLMRKGQDSIEPVPGQKGKKKAV-EQRDFIGVDSTGKRL---LFMAN 172 ++++ + L + Q GK +A+ E +D + + ++ + Sbjct: 122 LIEVSNKTGIGMITLHVDNPTGYGRIVRQDGKIQAIVEHKDATEAQRQIQEINTGIYCVS 181 Query: 173 EADLDEELVIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSEL---I 229 A L E L + ++ + Y L + + + I SI+ EL + Sbjct: 182 NAKLHEWL---PKLSNENAQGE----------YYLTDIVAMAVADGLEIASIQPELAFEV 228 Query: 230 PYLVRKQFSSASSQQGQEEKEEDLKKKELKSLDIYSF-----IKEANTLNLAPYDACWNA 284 + + +A ++ Q+++ ++L ++ + D F +K + + + Sbjct: 229 EGVNDRLQLAALEREFQKQQAKELMQQGVTFADPARFDLRGTVKVGHDVRIDVNVIIEGN 288 Query: 285 CRGDRWEDLSRSQVRCYVHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPPVHSSA 344 C + ++ I+K + + + Y + V + + P + Sbjct: 289 CELGDFVEIGAGC------ILKNTTIAAGTKVQAYSVFDGAVVGENTQIGPFARLRPGAK 342 Query: 345 QIVSKHLVG----VDSLIGPETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEE 400 H+ ++ IG ++ + + + IG+ I N + Sbjct: 343 LANEVHIGNFVEVKNTTIGLGSKANHFTYLGDAEIGAESNIGAGTITCNY---------D 393 Query: 401 GSNIQGSVICNNAVIEKGADI 421 G+N + I + I + + Sbjct: 394 GANKHKTTIGDAVFIGSNSSL 414 Score = 36.0 bits (81), Expect = 0.034, Method: Composition-based stats. Identities = 22/95 (23%), Positives = 31/95 (32%), Gaps = 16/95 (16%) Query: 352 VGVDSLIGPETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEGSNIQGSVICN 411 VG D I I +G I + N + V+ S G+V+ Sbjct: 273 VGHDVRIDVNVIIEGNCE-----LGDFVEIGAGCILKNTTIAAGTKVQAYSVFDGAVVGE 327 Query: 412 NAVIEKGADIKDCLIGSGQRIEAKAKRVNEVIVGN 446 N I A ++ AK NEV +GN Sbjct: 328 NTQIGPFARLR-----------PGAKLANEVHIGN 351 >1HM0-A nrPDB Length = 468 Score = 64.1 bits (154), Expect = 1e-10, Method: Composition-based stats. Identities = 68/470 (14%), Positives = 159/470 (33%), Gaps = 96/470 (20%) Query: 5 AVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQKALC 64 A+++A G G+RM +PK L V ++ + + + E+ + V + Sbjct: 14 AIILAAGKGTRMKS---DLPKVLHKVAGISMLEHVFRSVGAIQPEKTVTVVGHKAEL--- 67 Query: 65 AEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLK---TDVLVLSCD--LITDVALHEVVD 119 + + + +GT ++ P L+ LV++ D LIT +L ++D Sbjct: 68 --VEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGDTPLITGESLKNLID 125 Query: 120 LFRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMANEADLDEE 179 + +L + + R ++ R++ + D +++ Sbjct: 126 FHINHKNVATILTAETDNPFGY------------GRIVRNDNAEVLRIVEQKDATDFEKQ 173 Query: 180 LVIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYLVRKQFSS 239 + +TG Y+ D ++ +I + Sbjct: 174 IK------------EINTG----------TYVFDNERLFEALKNINTN------------ 199 Query: 240 ASSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWEDLSRSQVR 299 + QG+ + + + ++ + +L D A E + R ++ Sbjct: 200 --NAQGEYYITDVIGIFRETGEKVGAYTLKDFDESLGVNDRVALATA----ESVMRRRIN 253 Query: 300 CYVHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPPVHSSAQIVSKHLVGVDSLIG 359 + H++ S V+ Y++ + ++ E + ++ + + +G ++++ Sbjct: 254 -HKHMVNG--VSFVNPEATYIDIDVEIA--------PEVQIEANVILKGQTKIGAETVLT 302 Query: 360 PET-----QIGEKSSIKRSVIGSSCLIKDRVTIT-------NCLLMNSVTVEEGSNIQGS 407 T IG + I S+I + D VT+ N L V + ++GS Sbjct: 303 NGTYVVDSTIGAGAVITNSMI-EESSVADGVTVGPYAHIRPNSSLGAQVHIGNFVEVKGS 361 Query: 408 VICNNAVIEKGADIKDCLIGSGQ-------RIEAKAKRVNEVIVGNDQLM 450 I N I +C +GS + K + ++G++ + Sbjct: 362 SIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKYKTVIGDNVFV 411 >4MND-A nrPDB Length = 479 Score = 63.3 bits (152), Expect = 2e-10, Method: Composition-based stats. Identities = 27/107 (25%), Positives = 46/107 (42%), Gaps = 6/107 (5%) Query: 3 FQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQKA 62 +AV++A G G+R+ +PKPL+ VG +I + LL E I+V +R Sbjct: 41 MKAVILAAGLGTRL----GGVPKPLVRVGGCEIILRTMKLLSPH-VSEFIIVASRYADD- 94 Query: 63 LCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLI 109 + A K K + D + G SL ++ ++ D + Sbjct: 95 IDAFLKDKGFNYKIVRHDRPEKGNGYSLLVAKNHVEDRFILTMGDHV 141 >2PA4-A nrPDB Length = 323 Score = 59.9 bits (143), Expect = 2e-09, Method: Composition-based stats. Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 1/64 (1%) Query: 5 AVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQKALC 64 VV A G G+R T ++PK LLPV + P I +G + ++T + + + Sbjct: 15 VVVPAAGLGTRFLPATKTVPKELLPVVDTPGIELIAAEAAELGATRLAIITAPN-KAGVL 73 Query: 65 AEFK 68 A F+ Sbjct: 74 AHFE 77 >5W6J-A nrPDB Length = 420 Score = 57.6 bits (137), Expect = 1e-08, Method: Composition-based stats. Identities = 76/449 (16%), Positives = 132/449 (29%), Gaps = 101/449 (22%) Query: 5 AVVMAVGGGSRMTDLTSSIPKPLLPVGNKP-LIWYPLNLLERVGFEEVIVVTTRDVQKAL 63 A V+A G GSR+ +LT KP + G K +I + L+ G + V T + Sbjct: 15 AYVLAGGRGSRLKELTDRRAKPAVYFGGKARIIDFALSNALNSGIRRIGVATQYKAHSLI 74 Query: 64 ------CAEFKMKMKPDIVCIPDDADM-------GTADSLRY----IYPKLKTDVLVLSC 106 F+ + +P + GTAD++ I P +++L+ Sbjct: 75 RHLQRGWDFFRPERNESFDILPASQRVSETQWYEGTADAVYQNIDIIEPYAPEYMVILAG 134 Query: 107 DLITDVALHEVVDLFRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDF--IGVDSTG 164 D I + ++ DS V + +E F + V+ Sbjct: 135 DHIYKMDYEYMLQQH--------------VDSGADVTIGCLEVPRMEATGFGVMHVNEKD 180 Query: 165 KRLLFMANEADLDEELVIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSI 224 + + F+ AD I G+ H L + + + S Sbjct: 181 EIIDFIEKPADP-------PGIPGNEGFALASMGIYVFHTKFLMEALRRDAADPTSSRDF 233 Query: 225 RSELIPYLVRKQFSSASSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNA 284 ++IPY+V + A + F E ++ DA W Sbjct: 234 GKDIIPYIVEHGKAVAHRFADSCVRS--------------DFEHEPYWRDVGTIDAYWQ- 278 Query: 285 CRGDRWEDLSRSQVRCYVHIMKEGLCSRVSTLGLYMEANRQVPKLLSA-LCPEEPPVHSS 343 L V L +Y + P A + P VH Sbjct: 279 --------------------ANIDLTDVVPDLDIYD---KSWPIWTYAEITPPAKFVHDD 315 Query: 344 AQIVSKHLVGVDSLIGPETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEGSN 403 + SV+ C+I + LL V S Sbjct: 316 EDRRGSAV--------------------SSVVSGDCII-SGAALNRSLLFTGVRANSYSR 354 Query: 404 IQGSVICNNAVIEKGADIKDCLIGSGQRI 432 ++ +V+ + I + A + + +I G I Sbjct: 355 LENAVVLPSVKIGRHAQLSNVVIDHGVVI 383 >1FWY-A nrPDB Length = 331 Score = 54.1 bits (128), Expect = 1e-07, Method: Composition-based stats. Identities = 60/399 (15%), Positives = 122/399 (30%), Gaps = 77/399 (19%) Query: 2 EFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQK 61 V++A G G+RM +PK L + K ++ + ++ +G V +V Sbjct: 5 AMSVVILAAGKGTRMYS---DLPKVLHTLAGKAMVQHVIDAANELGAAHVHLVYG---HG 58 Query: 62 ALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEVVDLF 121 + +K ++ + +GT +++ P D +L L DV L V L Sbjct: 59 GDLLKQALK-DDNLNWVLQAEQLGTGHAMQQAAPFFADDEDILM--LYGDVPLISVETLQ 115 Query: 122 RAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMANEADLDEELV 181 R DA + ++ G + + ++ + D ++ Sbjct: 116 RLRDAKPQGGIGLLTVKLDDPTGYGRITRE---------NGKVTGIVEHKDATDEQRQIQ 166 Query: 182 IKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYLVRKQFSSAS 241 +TG++ A+ +K+++ N +++I Sbjct: 167 ------------EINTGILIANGADMKRWLAKLTNNNAQGEYYITDII------------ 202 Query: 242 SQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWEDLSRSQVRCY 301 + I + L+ + N + R E + +S+ Sbjct: 203 ----------------ALAYQEGREIVAVHPQRLSEVEGVNNRLQLSRLERVYQSEQAEK 246 Query: 302 VHIMKEGLCSRVS-TLGLYMEANRQVPKLLSALCPEEPPVHSSAQIVSKHLVGVDSLIGP 360 + + L L + R V + ++ I +G IG Sbjct: 247 LLLAGVMLRDPARFDLRGTLTHGRDV------------EIDTNVIIEGNVTLGHRVKIGT 294 Query: 361 ETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVE 399 I K SVIG C I + + L + T+ Sbjct: 295 GCVI------KNSVIGDDCEISPYTVVEDANLAAACTIG 327 Score = 32.5 bits (72), Expect = 0.36, Method: Composition-based stats. Identities = 9/59 (15%), Positives = 23/59 (38%), Gaps = 1/59 (1%) Query: 359 GPETQIGEKSSIKRSV-IGSSCLIKDRVTITNCLLMNSVTVEEGSNIQGSVICNNAVIE 416 G + +I I+ +V +G I I N ++ + + + ++ + + I Sbjct: 269 GRDVEIDTNVIIEGNVTLGHRVKIGTGCVIKNSVIGDDCEISPYTVVEDANLAAACTIG 327 Score = 30.2 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 16/63 (25%), Positives = 25/63 (39%), Gaps = 1/63 (1%) Query: 353 GVDSLIGPETQIGEKSSIKRSV-IGSSCLIKDRVTITNCLLMNSVTVEEGSNIQGSVICN 411 G D I I ++ V IG+ C+IK+ V +C + VE+ + I Sbjct: 269 GRDVEIDTNVIIEGNVTLGHRVKIGTGCVIKNSVIGDDCEISPYTVVEDANLAAACTIGP 328 Query: 412 NAV 414 A Sbjct: 329 FAR 331 Score = 29.0 bits (63), Expect = 4.0, Method: Composition-based stats. Identities = 11/41 (26%), Positives = 19/41 (46%), Gaps = 1/41 (2%) Query: 395 SVTVEEGSNIQGSV-ICNNAVIEKGADIKDCLIGSGQRIEA 434 V ++ I+G+V + + I G IK+ +IG I Sbjct: 271 DVEIDTNVIIEGNVTLGHRVKIGTGCVIKNSVIGDDCEISP 311 >2X5Z-A nrPDB Length = 336 Score = 51.0 bits (120), Expect = 9e-07, Method: Composition-based stats. Identities = 31/108 (28%), Positives = 47/108 (43%), Gaps = 3/108 (2%) Query: 3 FQAVVMAVGGGSRMTDL-TSSIPKPLLP-VGNKPLIWYPLN-LLERVGFEEVIVVTTRDV 59 +A+++A G G R L T PK L GNK L+ + +LE + ++VIVVT +D Sbjct: 2 MKALILAGGSGERFWPLSTPETPKQFLKLFGNKSLMRWTFERVLEEMDPKDVIVVTHKDY 61 Query: 60 QKALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCD 107 + E +I+ P + A + VLVL D Sbjct: 62 VERTKKELPELPDENIIAEPMKKNTAPACFIGTKLADDDEPVLVLPAD 109 >2XWM-A nrPDB Length = 223 Score = 51.0 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 25/104 (24%), Positives = 41/104 (39%), Gaps = 6/104 (5%) Query: 1 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQ 60 M AVV A G G R+ + PK + +G PL+ + L+ L G + IV+ V Sbjct: 1 MATVAVVPAAGSGERLR---AGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVIA---VP 54 Query: 61 KALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVL 104 AL E K+ + I T + + +++ Sbjct: 55 PALTDESKLVFGGEDSVIVSGGVDRTESVALALEAAGDAEFVLV 98 >3TWD-A nrPDB Length = 222 Score = 50.6 bits (119), Expect = 1e-06, Method: Composition-based stats. Identities = 20/106 (18%), Positives = 46/106 (43%), Gaps = 2/106 (1%) Query: 343 SAQIVSKHLVGVDSLIGPETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEGS 402 +I + ++ + +G +IG IK SVIG C I + + L + T+ + Sbjct: 40 DVEIDTNVIIEGNVTLGHRVKIGTGCVIKNSVIGDDCEISPYTVVEDANLAAACTIGPFA 99 Query: 403 NIQ-GSVICNNAVIEKGADIKDCLIGSGQRIEAKAKRVNEVIVGND 447 ++ G+ + A + ++K +G G + + + +G++ Sbjct: 100 RLRPGAELLEGAHVGNFVEMKKARLGKGSKA-GHLTYLGDAEIGDN 144 >4IHG-A nrPDB Length = 348 Score = 49.8 bits (117), Expect = 2e-06, Method: Composition-based stats. Identities = 22/149 (14%), Positives = 55/149 (36%), Gaps = 43/149 (28%) Query: 340 VHSSAQIVSKHLVGVDSLIGPETQIGEKSSIKRSVIGSSCLIKDRVTI-TNCLLMNSVTV 398 + ++A++ + +G +++I ++G+ +IG+ C + I L +VT+ Sbjct: 113 IDATAKLGNNVSIGANAVIESGVELGD-----NVIIGAGCFVGKNSKIGAGSRLWANVTI 167 Query: 399 EEGSNI-QGSVICNNAVIEK------------------------------------GADI 421 I Q +I + V+ + Sbjct: 168 YHEIQIGQNCLIQSGTVVGADGFGYANDRGNWVKIPQIGRVIIGDRVEIGACTTIDRGAL 227 Query: 422 KDCLIGSGQRIEAKAKRVNEVIVGNDQLM 450 D +IG+G I+ + + + V++G++ + Sbjct: 228 DDTIIGNGVIIDNQCQIAHNVVIGDNTAV 256 Score = 44.8 bits (104), Expect = 8e-05, Method: Composition-based stats. Identities = 22/103 (21%), Positives = 35/103 (33%), Gaps = 16/103 (15%) Query: 342 SSAQIVSKHLVGVDSLIGPETQIGEKSS--------------IKRSVIGSSCLIKDRVTI 387 ++ I + +G + LI T +G I R +IG I TI Sbjct: 163 ANVTIYHEIQIGQNCLIQSGTVVGADGFGYANDRGNWVKIPQIGRVIIGDRVEIGACTTI 222 Query: 388 TNCLLMNSVTVEEGSNIQG-SVICNNAVIEKGADIKDCLIGSG 429 L + + G I I +N VI + +I +G Sbjct: 223 DRGAL-DDTIIGNGVIIDNQCQIAHNVVIGDNTAVAGGVIMAG 264 >1VPA-A nrPDB Length = 234 Score = 49.5 bits (116), Expect = 3e-06, Method: Composition-based stats. Identities = 40/214 (18%), Positives = 85/214 (39%), Gaps = 18/214 (8%) Query: 5 AVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQKALC 64 A+++A G G RM + ++PK L + + L YPL+ + + +V+ TR + Sbjct: 16 AILLAAGKGERM---SENVPKQFLEIEGRMLFEYPLSTFLKSEAIDGVVIVTRREWFEVV 72 Query: 65 AEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCD---LITDVALHEVVDLF 121 + K + D + S K +++ + + EV+ Sbjct: 73 EKRVFHEKVLGIVEGGDTRSQSVRSALEFLEKFSPSYVLVHDSARPFLRKKHVSEVLRRA 132 Query: 122 RAYDA------SLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFI--GVDSTGKRLLFMANE 173 R A + L+R D IE +P +KG + + + F + + A++ Sbjct: 133 RETGAATLALKNSDALVRVENDRIEYIP-RKGVYRILTPQAFSYEILKKAHENGGEWADD 191 Query: 174 ADLDEELVIKGSILQKHP---RIRFHTGLVDAHL 204 + ++L +K ++++ P ++ F L A + Sbjct: 192 TEPVQKLGVKIALVEGDPLCFKVTFKEDLELARI 225 >2CU2-A nrPDB Length = 337 Score = 47.9 bits (112), Expect = 1e-05, Method: Composition-based stats. Identities = 31/117 (26%), Positives = 52/117 (44%), Gaps = 10/117 (8%) Query: 1 MEFQAVVMAVGGGSRMTDLTS-SIPKPLLPVG-NKPLIWYPLNLLERVGFEEVIVVTTRD 58 M+ A+VMA G G R+ L+ PKP LP+ K L+ L L + E ++ R Sbjct: 1 MKTYALVMAGGRGERLWPLSREDRPKPFLPLFEGKTLLEATLERLAPLVPPERTLLAVRR 60 Query: 59 VQKALCAEF----KMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITD 111 Q+A+ + ++ ++P +G A++L+ +L LVL D Sbjct: 61 DQEAVARPYADGIRLLLEPLGRDTAGAVLLGVAEALKEGAERL----LVLPADHYVG 113 >2MZB-A nrPDB Length = 196 Score = 47.5 bits (111), Expect = 1e-05, Method: Composition-based stats. Identities = 29/146 (19%), Positives = 60/146 (41%), Gaps = 16/146 (10%) Query: 3 FQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRD---V 59 A++MA G G+RM + KPL+ + + LI Y ++ L + + + T+ + Sbjct: 1 MDALIMAGGKGTRM----GGVEKPLIKLCGRCLIDYVVSPLLKSKVNNIFIATSPNTPKT 56 Query: 60 QKALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLIT--DVALHEV 117 ++ + + +K + + D + G + L LV+S DLI ++ + Sbjct: 57 KEYINSAYK---DYKNIVVIDTSGKGYIEDLNECIGYFSEPFLVVSSDLINLKSKIINSI 113 Query: 118 VDLF----RAYDASLAMLMRKGQDSI 139 VD F A+ + ++ Sbjct: 114 VDYFYCIKAKTPDVEALAVMIPKEKY 139 >4E79-A nrPDB Length = 357 Score = 46.4 bits (108), Expect = 2e-05, Method: Composition-based stats. Identities = 31/187 (16%), Positives = 59/187 (31%), Gaps = 43/187 (22%) Query: 303 HIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPPVHSSAQIVSKHLVGVDSLIGPET 362 H+ ++ V L V + + S+A+I ++ + IG Sbjct: 72 HLPEKDNFIIVDNPYLAFAILTHVFDKKISST----GIESTARIHPSAVISETAYIGHYV 127 Query: 363 QIGEKSSI-KRSVI------------GSSCLIKDRVTITNCLLMNS--------VTVEEG 401 IGE + +VI G C I VTIT + V EG Sbjct: 128 VIGENCVVGDNTVIQSHTKLDDNVEVGKDCFIDSYVTITGSSKLRDRVRIHSSTVIGGEG 187 Query: 402 -------------SNIQGSVICNNAVIEKGAD-----IKDCLIGSGQRIEAKAKRVNEVI 443 + + +I N+ I + + ++ G I+ + + V Sbjct: 188 FGFAPYQGKWHRIAQLGSVLIGNDVRIGSNCSIDRGALDNTILEDGVIIDNLVQIAHNVH 247 Query: 444 VGNDQLM 450 +G++ + Sbjct: 248 IGSNTAI 254 >4G3P-A nrPDB Length = 501 Score = 46.4 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 78/460 (16%), Positives = 142/460 (30%), Gaps = 58/460 (12%) Query: 5 AVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQ--KA 62 +V+A G G+RM PK L + + ++ + L+ + ++ + +IVV D Q Sbjct: 15 VLVLAAGPGTRMRS---DTPKVLHTLAGRSMLSHVLHAIAKLAPQRLIVVLGHDHQRIAP 71 Query: 63 LCAEFKMKMKPDIVCIPDDADMGTADS----LRYIYPKLKTDVLVLSCD--LITDVALHE 116 L E + I D +GT + L + +V+V S D L+ L + Sbjct: 72 LVGELADTLGRTIDVALQDRPLGTGHAVLCGLSALPDDYAGNVVVTSGDTPLLDADTLAD 131 Query: 117 VVDLFRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMANEADL 176 ++ RA A++ +L D + + V I + E Sbjct: 132 LIATHRAVSAAVTVLTTTLDDPFGYGRILRTQDHEVMA---IVEQTDATP---SQREIRE 185 Query: 177 DEELVIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYLVRKQ 236 + G+ + L+ + N +++I L Sbjct: 186 ------------------VNAGVYAFDIAALRSALSRLSSNNAQQELYLTDVIAIL---- 223 Query: 237 FSSASSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYD--ACWNACRGDRWEDLS 294 S + + L + + E N +A + W D+ Sbjct: 224 RSDGQTVHASHVDDSALVAGVNNRVQLAELASELNRRVVAAHQLAGVTVVDPATTWIDVD 283 Query: 295 RSQVRCYVHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPPVHSSA--QIVSKHLV 352 + R V L R G R V + L +S S + Sbjct: 284 VTIGRDTVIHPGTQLLGRTQIGG------RCVVGPDTTLTDVAVGDGASVVRTHGSSSSI 337 Query: 353 GVDSLIG------PETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEGSNIQG 406 G + +G P T +G + V + I + + + + E SNI Sbjct: 338 GDGAAVGPFTYLRPGTALGADGKLGAFVEVKNSTIGTGTKVPHLTYVGDADIGEYSNIGA 397 Query: 407 SVICNNAVIEKGADIKDCLIGSGQRIEAKAKRVNEVIVGN 446 S + N G + +GS R + V V +G+ Sbjct: 398 SSVFVNY---DGTSKRRTTVGSHVRTGSDTMFVAPVTIGD 434 >2QKX-A nrPDB Length = 391 Score = 46.4 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 35/170 (20%), Positives = 66/170 (38%), Gaps = 11/170 (6%) Query: 5 AVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQ--KA 62 +V+A G G+RM PK L + + ++ + L+ + ++ + +IVV D Q Sbjct: 11 VLVLAAGPGTRMRS---DTPKVLHTLAGRSMLSHVLHAIAKLAPQRLIVVLGHDHQRIAP 67 Query: 63 LCAEFKMKMKPDIVCIPDDADMGTADS----LRYIYPKLKTDVLVLSCD--LITDVALHE 116 L E + I D +GT + L + +V+V S D L+ L + Sbjct: 68 LVGELADTLGRTIDVALQDRPLGTGHAVLCGLSALPDDYAGNVVVTSGDTPLLDADTLAD 127 Query: 117 VVDLFRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKR 166 ++ RA A++ +L D + + V + +R Sbjct: 128 LIATHRAVSAAVTVLTTTLDDPFGYGRILRTQDHEVMAIVEQTDATPSQR 177 Score = 36.8 bits (83), Expect = 0.018, Method: Composition-based stats. Identities = 36/181 (19%), Positives = 67/181 (37%), Gaps = 23/181 (12%) Query: 274 NLAPYDACWNACRGDRWEDLSRSQVRCYV-HIMKEGLCSRVST----LGLYMEANRQVPK 328 L+ +A D L + H+ L + V+ L E NR+V Sbjct: 200 RLSSNNAQQELYLTDVIAILRSDGQTVHASHVDDSALVAGVNNRVQLAELASELNRRVVA 259 Query: 329 LLSALCPEEPPVHSSAQIVSKHLVGVDSLIGPETQIGEKSSIKRSVIGSSCLIKDRVTIT 388 L ++ I +G D++I P TQ+ + R+ IG C++ T+T Sbjct: 260 -AHQLAGVTVVDPATTWIDVDVTIGRDTVIHPGTQL-----LGRTQIGGRCVVGPDTTLT 313 Query: 389 NCLLMNSVTVEEGSNI-----QGSVICNNAVIEKGADIK-DCLIGSGQRIEAKAKRVNEV 442 V V +G+++ S I + A + ++ +G+ ++ A + N Sbjct: 314 ------DVAVGDGASVVRTHGSSSSIGDGAAVGPFTYLRPGTALGADGKLGAFVEVKNST 367 Query: 443 I 443 I Sbjct: 368 I 368 >4JIS-A nrPDB Length = 247 Score = 45.6 bits (106), Expect = 5e-05, Method: Composition-based stats. Identities = 28/157 (17%), Positives = 67/157 (42%), Gaps = 5/157 (3%) Query: 5 AVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVG-FEEVIVVTTRDVQKAL 63 A ++A G GSRM ++ ++PK LP+ +P+I + + F+++++V+ ++ Sbjct: 6 AEILAGGKGSRMGNV--NMPKQFLPLNKRPIIIHTVEKFLLNDRFDKILIVSPKEWINHT 63 Query: 64 CAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEVVDLFRA 123 K + D + + +S+ ++ + + D+I R Sbjct: 64 KDILKKFIGQDDRLVVVEGGSDRNESIMSGIRYIEKEFGIQDNDVIITHDSVRPFLTHRI 123 Query: 124 YDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGV 160 D ++ +++ G +++ V A E ++FI Sbjct: 124 IDENIDAVLQYG--AVDTVISAIDTIIASEDQEFISD 158 >3PMO-A nrPDB Length = 372 Score = 44.8 bits (104), Expect = 7e-05, Method: Composition-based stats. Identities = 29/138 (21%), Positives = 50/138 (36%), Gaps = 27/138 (19%) Query: 340 VHSSAQIVSKHLVGVDSLIGPETQIGEKSSI-KRSVIGSS------------CLIKDRVT 386 V SA + + ++ + IG IG I RSVIG I RV+ Sbjct: 134 VDPSASVGAYAVIESGARIGAGVSIGAHCVIGARSVIGEGGWLAPRVTLYHDVTIGARVS 193 Query: 387 ITNCLLM--NSVTVEEG-------SNIQGSVICNNAVIEKGAD-----IKDCLIGSGQRI 432 I + ++ + I G I ++ I + D LIG+G ++ Sbjct: 194 IQSGAVIGGEGFGFANEKGVWQKIAQIGGVTIGDDVEIGANTTIDRGALSDTLIGNGVKL 253 Query: 433 EAKAKRVNEVIVGNDQLM 450 + + + V +G+ M Sbjct: 254 DNQIMIAHNVQIGDHTAM 271 >1XHD-A nrPDB Length = 173 Score = 44.8 bits (104), Expect = 8e-05, Method: Composition-based stats. Identities = 28/132 (21%), Positives = 53/132 (40%), Gaps = 16/132 (12%) Query: 329 LLSALCPEEPPVHSSAQIVSKHLVGVDSLIGPETQIGEKSSIKR----SVIGSSCLIKDR 384 ++ ++P + SSA I + D +G E+ I + I+ ++IG ++D+ Sbjct: 4 MIYPYKEKKPKIASSAFIADYVTITGDVYVGEESSIWFNTVIRGDVSPTIIGDRVNVQDQ 63 Query: 385 VTITNC-----LLMNSVTVEEGSNIQGSVICNNAVIEKGADIKD-------CLIGSGQRI 432 T+ +L + VTV + I +A+I G+ I D IG+G + Sbjct: 64 CTLHQSPQYPLILEDDVTVGHQVILHSCHIKKDALIGMGSIILDGAEIGEGAFIGAGSLV 123 Query: 433 EAKAKRVNEVIV 444 K + Sbjct: 124 SQGKKIPPNTLA 135 >3F1C-A nrPDB Length = 246 Score = 44.8 bits (104), Expect = 8e-05, Method: Composition-based stats. Identities = 20/122 (16%), Positives = 51/122 (41%), Gaps = 8/122 (6%) Query: 5 AVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVG-FEEVIVVTTRDVQKAL 63 A ++A G G+RM +++ +PK LP+ KP+I + + F+++++ + ++ Sbjct: 6 AQILAGGKGTRMGNVS--MPKQFLPLNGKPIIVHTVEKFILNTRFDKILISSPKEWMNHA 63 Query: 64 CAEFKMKMKPDIVC-----IPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEVV 118 K + D + + + L D ++++ D + H ++ Sbjct: 64 EDNIKKYISDDRIVVIEGGEDRNETIMNGIRFVEKTYGLTDDDIIVTHDAVRPFLTHRII 123 Query: 119 DL 120 + Sbjct: 124 EE 125 >4CVH-A nrPDB Length = 411 Score = 44.1 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 4/58 (6%) Query: 5 AVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLER-VGFEEVIVVTTRDVQK 61 AV+ A G G RM T PK P+ +PLI Y L LER ++++V T + + Sbjct: 9 AVLPAGGCGERMGVPT---PKQFCPILERPLISYTLQALERVCWIKDIVVAVTGENME 63 >1H7T-A nrPDB Length = 245 Score = 44.1 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 33/170 (19%), Positives = 59/170 (34%), Gaps = 18/170 (10%) Query: 5 AVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLN-LLERVGFEEVIVVTTRDVQKAL 63 +V+ GS KPLL + KP+I + L+ G EV V T + Sbjct: 4 VIVIPARYGSSRLPG-----KPLLDIVGKPMIQHVYERALQVAGVAEVWVATDDPRVEQA 58 Query: 64 CAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEVVDLFRA 123 F K + +D + GT D L + K++ D+ ++ E + R Sbjct: 59 VQAFGGK----AIMTRNDHESGT-DRLVEVMHKVEA-------DIYINLQGDEPMIRPRD 106 Query: 124 YDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMANE 173 + L + + + +A E V +T + L+ + Sbjct: 107 VETLLQGMRDDPALPVATLCHAISAAEAAEPSTVKVVVNTRQDALYFSRS 156 >3TQD-A nrPDB Length = 256 Score = 43.7 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 39/210 (18%), Positives = 73/210 (34%), Gaps = 36/210 (17%) Query: 1 MEFQAVVMAVGGGSRMTDLTSSIP-KPLLPVGNKPLIWYPLNLLERVGFEEVIV------ 53 MEF+ ++ A +R+ P K L+ + KP+I + + G EEV++ Sbjct: 8 MEFRVIIPARFDSTRL-------PGKALVDIAGKPMIQHVYESAIKSGAEEVVIATDDKR 60 Query: 54 -------------VTTRDVQKALCA------EFKMKMKPDIVCIPDDADMGTADSLRYIY 94 +T+ D Q + IVC+ D + D++R + Sbjct: 61 IRQVAEDFGAVVCMTSSDHQSGTERIAEAAVALGFEDDEIIVCLQGDEPLIPPDAIRKLA 120 Query: 95 PKLKTDVLVLSCDLITDVALHEVVDLFRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQ 154 L V L T + EV +LF + + + R P G+ ++ Sbjct: 121 EDLDEHDNVKVASLCT--PITEVDELFNPHSTKVVLNRRNYALYFSHAPIPWGRDTFSDK 178 Query: 155 RDFIGVDSTGKRL-LFMANEADLDEELVIK 183 + S + + ++ L+E L Sbjct: 179 ENLQLNGSHYRHVGIYAYRVGFLEEYLSWD 208 >3OAM-A nrPDB Length = 252 Score = 43.3 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 35/147 (23%), Positives = 59/147 (40%), Gaps = 19/147 (12%) Query: 1 MEFQAVVMAVGGGSRMTDLTSSIP-KPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDV 59 M F V+ A +R+ P KPL +G KP+I + + G + VI+ T + Sbjct: 1 MSFTVVIPARYQSTRL-------PGKPLADIGGKPMIQWVYEQAMQAGADRVIIATDDER 53 Query: 60 QKALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPK--LKTDVLVLS--CD--LITDVA 113 + F +VC+ + L + K + D +V++ D LI Sbjct: 54 VEQAVQAFG-----GVVCMTSPNHQSGTERLAEVVAKMAIPADHIVVNVQGDEPLIPPAI 108 Query: 114 LHEVVDLFRAYDASLAMLMRKGQDSIE 140 + +V D A A +A L + +D E Sbjct: 109 IRQVADNLAACSAPMATLAVEIEDEAE 135 >4MFG-A nrPDB Length = 168 Score = 43.3 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 34/132 (25%), Positives = 56/132 (42%), Gaps = 30/132 (22%) Query: 332 ALCPEEPPVHSSAQIVSKHLVGVDSLI----------GPETQIGEKSSI---------KR 372 L E V SA ++ +G DS I GP T IGE ++I Sbjct: 13 PLIDESVFVAKSADVIGNVKIGKDSSIWYNAVVRGDEGPIT-IGENTNIQDCSIVHGDTE 71 Query: 373 SVIGSSCLIKDRVTITNCLLMNSVTVEEGSNIQGSVICNNAVIEKGADIKDCLIGSGQRI 432 ++IG++ + R + C + ++V + G S+I +NA I + LIG+G I Sbjct: 72 TIIGNNVTVGHRSIVHGCKISDNVLIGMG-----SIILDNAEIGEYT-----LIGAGTLI 121 Query: 433 EAKAKRVNEVIV 444 + K V++ Sbjct: 122 TSNKKFPPGVLI 133 Score = 30.6 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 19/112 (16%), Positives = 35/112 (31%), Gaps = 12/112 (10%) Query: 349 KHLVGVDSLIGPETQI-GEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEGSNIQGS 407 + + LI + I IG I + +T+ E +NIQ Sbjct: 6 RDYLEDKPLIDESVFVAKSADVIGNVKIGKDSSIWYNAVVRGD--EGPITIGENTNIQDC 63 Query: 408 ---------VICNNAVIEKGADIKDCLIGSGQRIEAKAKRVNEVIVGNDQLM 450 +I NN + + + C I I + ++ +G L+ Sbjct: 64 SIVHGDTETIIGNNVTVGHRSIVHGCKISDNVLIGMGSIILDNAEIGEYTLI 115 >3T57-A nrPDB Length = 305 Score = 42.5 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 25/135 (18%), Positives = 54/135 (40%), Gaps = 21/135 (15%) Query: 337 EPPVHSSAQIVSKHLVGVDSLIGPETQIGEKSSIKRSV-IGSSCLIKDRVTI-TNCLLMN 394 E +H SA + ++G +GP IG + + S + + +C+LM Sbjct: 7 EVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMT 66 Query: 395 SVTVEEGS-----NIQGSVICNNAVIEKGA-DIK-----DCLIGSGQRIEAK-------- 435 V + ++I ++AV+ D+K +C + G E + Sbjct: 67 GAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRS 126 Query: 436 AKRVNEVIVGNDQLM 450 +K ++ ++G++ L+ Sbjct: 127 SKPSDKTVIGDNNLI 141 >5F42-A nrPDB Length = 280 Score = 41.8 bits (96), Expect = 6e-04, Method: Composition-based stats. Identities = 27/114 (23%), Positives = 45/114 (39%), Gaps = 12/114 (10%) Query: 340 VHSSAQIVSKHLVGVDSLIGPETQIGEKSSIKRSV-IGSSCLIKDRVTITNCLLMNSVTV 398 VH SA+I ++G +IG IGE + +K V IG + +I I ++ Sbjct: 8 VHESAKIADSAIIGPFCVIGKNVVIGENTELKSHVTIGDNAVIGKNNRI-----FQYASI 62 Query: 399 EEGSNIQGSVICN--NAVIEKGADIKDCLIGSGQRIEAKAKRVNEVIVGNDQLM 450 + + VI I++C G AK + VGN+ ++ Sbjct: 63 GDDPIDYTYKKGDFSQVVIGDNNIIRECATIHG----GTAKEIGVTSVGNNNII 112 >3K8D-A nrPDB Length = 264 Score = 41.8 bits (96), Expect = 6e-04, Method: Composition-based stats. Identities = 29/174 (16%), Positives = 59/174 (33%), Gaps = 20/174 (11%) Query: 1 MEFQAVVMAVGGGSRMTDLTSSIP-KPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDV 59 M F ++ A +R+ P KPL+ + KP+I + L G E +IV T Sbjct: 17 MSFVVIIPARYASTRL-------PGKPLVDINGKPMIVHVLERARESGAERIIVAT---- 65 Query: 60 QKALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPK--LKTDVLVLSCDLITDVALHEV 117 ++ VC+ + L + K D ++++ + + Sbjct: 66 -DHEDVARAVEAAGGEVCMTRADHQSGTERLAEVVEKCAFSDDTVIVNVQGDEPMIPATI 124 Query: 118 VDLFRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMA 171 + + + R+ + VP ++ + +D+ G L F Sbjct: 125 I-----RQVADNLAQRQVGMATLAVPIHNAEEAFNPNAVKVVLDAEGYALYFSR 173 >1VH3-A nrPDB Length = 262 Score = 39.1 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 29/142 (20%), Positives = 55/142 (38%), Gaps = 9/142 (6%) Query: 1 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQ 60 M F ++ A SR+ KPL + KP+I + + G VI+ T + Sbjct: 1 MSFTVIIPARFASSRLPG------KPLADIKGKPMIQHVFEKALQSGASRVIIATDNENV 54 Query: 61 KALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCD--LITDVALHEVV 118 + F ++ V + A+ + + ++ + D LI V + +V Sbjct: 55 ADVAKSFGAEVCMTSVNHNSGTER-LAEVVEKLAIPDNEIIVNIQGDEPLIPPVIVRQVA 113 Query: 119 DLFRAYDASLAMLMRKGQDSIE 140 D ++ ++A L K D+ E Sbjct: 114 DNLAKFNVNMASLAVKIHDAEE 135 >2XWN-A nrPDB Length = 233 Score = 38.7 bits (88), Expect = 0.006, Method: Composition-based stats. Identities = 12/43 (27%), Positives = 19/43 (44%), Gaps = 3/43 (6%) Query: 5 AVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVG 47 A+V A G G R+ +PK + + LI ++ L G Sbjct: 10 AIVPAAGSGERL---AVGVPKAFYQLDGQTLIERAVDGLLDSG 49 >4NAK-A nrPDB Length = 228 Score = 37.9 bits (86), Expect = 0.008, Method: Composition-based stats. Identities = 35/200 (17%), Positives = 69/200 (34%), Gaps = 20/200 (10%) Query: 5 AVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYP-LNLLERVGFEEVIVVTT---RDVQ 60 +++A G G RM S+PK +P+ +P+ Y +E++VV RD+ Sbjct: 7 VILLAGGQGKRMK---MSMPKQYIPLLGQPIALYSFFTFSRMPEVKEIVVVCDPFFRDIF 63 Query: 61 KALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEVVDL 120 + + + I + + L+ I + ++++ + V +V + Sbjct: 64 EEYEESIDVDLSFAIPGKERQDSVYSG--LQEID--VNSELVCIHDSARPLVNTEDVEKV 119 Query: 121 FRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMANEADLDEEL 180 + A A ++ K K V + K L M + EL Sbjct: 120 LKDGSAVGAAVLGVP---------AKATIKEVNSDSLVVKTLDRKTLWEMQTPQVIKPEL 170 Query: 181 VIKGSILQKHPRIRFHTGLV 200 + KG L K + + Sbjct: 171 LKKGFELVKSEGLEVTDDVS 190 >2QH5-A nrPDB Length = 308 Score = 37.9 bits (86), Expect = 0.008, Method: Composition-based stats. Identities = 24/123 (19%), Positives = 51/123 (41%), Gaps = 9/123 (7%) Query: 1 MEFQAVVMAVGGGSRMTDLTSSI-PKPLLPVGN-KPLIWYPLNLLERVGFEEVIVVTTRD 58 ++ + ++++ G G R+ L+ S+ PK L + + K L L+ + ++ + Sbjct: 3 LKIKNILLSGGSGKRLWPLSRSLYPKQFLKLFDHKSLFE--LSFKRNASLVDETLIVCNE 60 Query: 59 VQKAL-CAEFKMKMKPDIV---CIPDDADMGTADSLRYIYPKLKTDVLVLSCD-LITDVA 113 L E K ++K V + A +L + + ++V D LI D+ Sbjct: 61 KHYFLALEEIKNEIKNKSVGFLLESLSKNTANAIALSALMSDKEDLLIVTPSDHLIKDLQ 120 Query: 114 LHE 116 +E Sbjct: 121 AYE 123 >2VSI-A nrPDB Length = 236 Score = 37.9 bits (86), Expect = 0.010, Method: Composition-based stats. Identities = 25/113 (22%), Positives = 52/113 (46%), Gaps = 10/113 (8%) Query: 5 AVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLN-LLERVGFEEVIVVTTRDVQKA- 62 A ++A G G+RM S++PK L +G++P++ + + + E+++V D Sbjct: 5 AGILAGGTGTRMG--ISNLPKQFLELGDRPILIHTIEKFVLEPSIEKIVVGVHGDWVSHA 62 Query: 63 --LCAEFKMKMKPDIVCIPDDADMGTA--DSLRYIYPK--LKTDVLVLSCDLI 109 L ++ K I+ AD T+ + + I L + +V++ D + Sbjct: 63 EDLVDKYLPLYKERIIITKGGADRNTSIKNIIEAIDAYRPLTPEDIVVTHDSV 115 >3JTJ-A nrPDB Length = 253 Score = 37.1 bits (84), Expect = 0.017, Method: Composition-based stats. Identities = 16/56 (28%), Positives = 26/56 (46%), Gaps = 8/56 (14%) Query: 1 MEFQAVVMAVGGGSRMTDLTSSIP-KPLLPVGNKPLIWYPLNLLERVGFEEVIVVT 55 M F A++ A +R+ P KPL + KP++ + + G + VIV T Sbjct: 4 MSFIAIIPARYASTRL-------PGKPLADIAGKPMVVHVMERALASGADRVIVAT 52 >4KT7-A nrPDB Length = 237 Score = 36.8 bits (83), Expect = 0.019, Method: Composition-based stats. Identities = 21/94 (22%), Positives = 43/94 (45%), Gaps = 5/94 (5%) Query: 5 AVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQKALC 64 A++ A G G RM I KP + VG + ++ L+ + RV + I++ R + + Sbjct: 12 AIITAAGSGLRMRS---KINKPYIEVGGRKVLEITLDTVSRVKEIDEIILVIRKDDEDII 68 Query: 65 AEFKMKMKPDIVCIPDDA--DMGTADSLRYIYPK 96 + K +I + ++ T + L+ + P+ Sbjct: 69 KDILEKYDGNIRYVYGSTTRELSTFEGLKALDPQ 102 >4EQY-A nrPDB Length = 283 Score = 36.8 bits (83), Expect = 0.020, Method: Composition-based stats. Identities = 23/135 (17%), Positives = 49/135 (36%), Gaps = 23/135 (17%) Query: 339 PVHSSAQIVSKHLVGVDSLIGPETQIGEKSSIK-RSVIGSSCLIKDRVTIT---NCLLMN 394 +H + ++ +VG + IG T IG S I+ + IG I ++ + Sbjct: 36 QLHETVEVGPYAIVGSNVTIGARTTIGSHSVIEGHTTIGEDNRIGHYASVGGRPQDMKYK 95 Query: 395 S----VTVEE-GSNIQGSVICNNAVIEKGADI--------------KDCLIGSGQRIEAK 435 + + + + + + I V + G DC +GS + + Sbjct: 96 DEPTRLVIGDRNTIREFTTIHTGTVQDAGVTTLGDDNWIMAYVHIGHDCRVGSHVVLSSN 155 Query: 436 AKRVNEVIVGNDQLM 450 A+ V +G+ ++ Sbjct: 156 AQMAGHVEIGDWAIV 170 >3MQG-A nrPDB Length = 192 Score = 36.0 bits (81), Expect = 0.039, Method: Composition-based stats. Identities = 23/121 (19%), Positives = 45/121 (37%), Gaps = 25/121 (20%) Query: 350 HLVGVDSLIGPETQIGEKSSIKRSV-------IGSSCLIKDRVTITNCL-------LMNS 395 + +++ +IG S I V IG C + V + N + + N+ Sbjct: 4 ATIHPTAIVDEGARIGAHSRIWHWVHICGGAEIGEGCSLGQNVFVGNRVRIGNRVKIQNN 63 Query: 396 VTVEEGSNIQGSVIC-----------NNAVIEKGADIKDCLIGSGQRIEAKAKRVNEVIV 444 V+V + ++ V C A IE+ ++ +D ++ G + A V + Sbjct: 64 VSVYDNVFLEDDVFCGPSMVFTNVYNPRAAIERKSEYRDTIVRQGATLGANCTVVCGATI 123 Query: 445 G 445 G Sbjct: 124 G 124 >3R0S-A nrPDB Length = 266 Score = 35.6 bits (80), Expect = 0.045, Method: Composition-based stats. Identities = 24/137 (17%), Positives = 46/137 (33%), Gaps = 35/137 (25%) Query: 340 VHSSAQIVSKHLVGVDSLIGPETQIGEKSSI--------------------KRSVIGSSC 379 V A+I + ++ + I +T IG+ S + VIG + Sbjct: 31 VSKDAKIGNNVVIKQGARILSDTTIGDHSRVFSYAIVGDIPQDISYKEEQKSGVVIGKNA 90 Query: 380 LIKDRVTI--------------TNCLLMNSVTVEEGSNIQGSVI-CNNAVIEKGADIKDC 424 I++ TI N +M + + ++I NNA + ++ D Sbjct: 91 TIREFATINSGTAKGDGFTRIGDNAFIMAYCHIAHDCLLGNNIILANNATLAGHVELGDF 150 Query: 425 LIGSGQRIEAKAKRVNE 441 + G + +V E Sbjct: 151 TVVGGLTPIHQFVKVGE 167 >3TIO-A nrPDB Length = 183 Score = 35.6 bits (80), Expect = 0.047, Method: Composition-based stats. Identities = 18/62 (29%), Positives = 30/62 (48%), Gaps = 2/62 (3%) Query: 359 GPETQIGEKSSIKRSVIGSSCLIKDRVTIT-NCLLMNSVTVEEGSNIQ-GSVICNNAVIE 416 G IGE ++ V+ C I +RV + +L++ VE+ I GS++ N +E Sbjct: 77 GNPLTIGEDVTVGHKVMLHGCTIGNRVLVGMGSILLDGAIVEDDVMIGAGSLVPQNKRLE 136 Query: 417 KG 418 G Sbjct: 137 SG 138 >5HS2-A nrPDB Length = 232 Score = 35.2 bits (79), Expect = 0.060, Method: Composition-based stats. Identities = 24/124 (19%), Positives = 51/124 (41%), Gaps = 11/124 (8%) Query: 1 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERV-GFEEVIVVTTRDV 59 M + V+ A G G RM + K + + P+I + L + + +++I+V Sbjct: 1 MSYDVVIPAAGQGKRMK---AGRNKLFIELKGDPVIIHTLRVFDSHRQCDKIILVINEQE 57 Query: 60 QKA---LCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHE 116 ++ L +++ + ++V D+ L+ +K + +VL D HE Sbjct: 58 REHFQQLLSDYPFQTSIELVAGGDERQHSVYKGLKA----VKQEKIVLVHDGARPFIKHE 113 Query: 117 VVDL 120 +D Sbjct: 114 QIDE 117 >2IUA-A nrPDB Length = 374 Score = 35.2 bits (79), Expect = 0.064, Method: Composition-based stats. Identities = 24/142 (16%), Positives = 54/142 (38%), Gaps = 22/142 (15%) Query: 331 SALCPEEPPVHSSAQIVSKHLVGVDSLIGPETQIGEKSSI-KRSVIGSSCLIKDRVTI-T 388 +A+ + + A + VG IG + IG S++ + S I +I++RV+I Sbjct: 136 TAIIEDHVCIEPYAVVCQHAHVGSACHIGSGSVIGAYSTVGEHSYIHPRVVIRERVSIGK 195 Query: 389 NCLLMNSVTVEEGS---------------NIQGSVICNNAVIEKGADI-----KDCLIGS 428 ++ + ++ +I ++ I I K ++ Sbjct: 196 RVIIQPGAVIGSCGFGYVTSAFGQHKHLKHLGKVIIEDDVEIGANTTIDRGRFKHSVVRE 255 Query: 429 GQRIEAKAKRVNEVIVGNDQLM 450 G +I+ + ++V VG ++ Sbjct: 256 GSKIDNLVQIAHQVEVGQHSMI 277 >3CJ8-A nrPDB Length = 236 Score = 34.8 bits (78), Expect = 0.074, Method: Composition-based stats. Identities = 30/176 (17%), Positives = 62/176 (35%), Gaps = 12/176 (6%) Query: 252 DLKKKELKSLDIYSFIKEA-NTLNLAPYDACWNACRGDRWEDLSRSQVRCYVHIMKEGLC 310 D KK+ L + + +KE + ++ C W D+ I + Sbjct: 15 DAKKQTLVKVTLKGQLKEVTFPETIKVFNNCKTGTLFGDWADVKPFLEANKEKIEDYVVE 74 Query: 311 SRVSTLGLYMEANRQVPKLLSA--LCPEEPPVHSSAQIVSKHLVGVDSLIGPETQIGEKS 368 + + + + + L E+ + A I+ ++ + +++G T I + Sbjct: 75 NDARNSAIPFLDLKDINARIEPGALIREKVEIGDQAVIMMGAILNIGAVVGAGTMIDMGA 134 Query: 369 SIK-RSVIGSSCLIKDRVTITNCLLMNS---VTVEEGSNIQGSVICNNAVIEKGAD 420 + R+ +G C I + + S V +E VI NAV+ +G Sbjct: 135 VLGGRATVGKHCHIGAGTVLAGVIEPPSAAPVVIENEV-----VIGANAVVLEGVR 185 >2PX7-A nrPDB Length = 236 Score = 34.8 bits (78), Expect = 0.078, Method: Composition-based stats. Identities = 13/46 (28%), Positives = 19/46 (41%), Gaps = 4/46 (8%) Query: 1 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERV 46 ME ++ A G G R+ PK L VG + L+ + L Sbjct: 24 MEVSVLIPAAGNGLRL----GRGPKAFLQVGGRTLLEWTLAAFRDA 65 >1VGT-A nrPDB Length = 238 Score = 34.8 bits (78), Expect = 0.088, Method: Composition-based stats. Identities = 18/82 (21%), Positives = 35/82 (42%), Gaps = 6/82 (7%) Query: 5 AVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVG-FEEVIVVTTRDVQKAL 63 AVV A G G RM + PK L +GN+ ++ + ++ L + V++ + + Sbjct: 12 AVVPAAGFGRRMQ---TECPKQYLSIGNQTILEHSVHALLAHPRVKRVVIAISP--GDSR 66 Query: 64 CAEFKMKMKPDIVCIPDDADMG 85 A+ + P I + + Sbjct: 67 FAQLPLANHPQITVVDGGDERA 88 >2JF2-A nrPDB Length = 264 Score = 34.4 bits (77), Expect = 0.090, Method: Composition-based stats. Identities = 19/88 (21%), Positives = 36/88 (40%), Gaps = 5/88 (5%) Query: 363 QIGEKSSIKRSV-IGSSCLIKDRVTITNC--LLMNSVTVEEGSNIQG-SVICNNAVIEKG 418 +IG+++ I+ SV I + +T LLM + + + ++ NNA + Sbjct: 87 EIGDRNRIRESVTIHRGTVQGGGLTKVGSDNLLMINAHIAHDCTVGNRCILANNATLAGH 146 Query: 419 ADIKD-CLIGSGQRIEAKAKRVNEVIVG 445 + D +IG + V+VG Sbjct: 147 VSVDDFAIIGGMTAVHQFCIIGAHVMVG 174 >3R8Y-A nrPDB Length = 240 Score = 34.1 bits (76), Expect = 0.13, Method: Composition-based stats. Identities = 15/80 (18%), Positives = 31/80 (38%), Gaps = 10/80 (12%) Query: 340 VHSSAQIVSKHLVGVDSLIGPETQIGEKSSIKR-------SVIGSSCLIKDRVTITNCLL 392 + +I ++ +++ I IGE S I + +G +C + + + Sbjct: 100 IRDHVEIGDNAVIMMNATINIGAVIGEGSMIDMNAVLGGRATVGKNCHVGAGAVLAGVIE 159 Query: 393 MNS---VTVEEGSNIQGSVI 409 S V VE+ I +V+ Sbjct: 160 PPSAKPVIVEDDVVIGANVV 179 >5JXX-A nrPDB Length = 257 Score = 34.1 bits (76), Expect = 0.15, Method: Composition-based stats. Identities = 22/117 (18%), Positives = 47/117 (40%), Gaps = 9/117 (7%) Query: 340 VHSSAQIVSKHLVGVDSLIGPETQIGEKSSI-KRSVIGSSCLIKDRVTIT-NCLLMNSVT 397 +H +A I ++ ++IGP +G+ S I +V+ S +I + I + + + Sbjct: 3 IHPTAIIDKSAMIADSAIIGPYCIVGKNSQIGAHTVLRSHVIIGENTKIGVHNDIYQFAS 62 Query: 398 VEEGSN-IQGSVICNNAVIEKGADIKD-CLIGSGQRIEAKAKRVNEVIVGNDQLMEI 452 + E ++ + I I++ C I G + +GN L+ + Sbjct: 63 IGENPQDLKYAGEQTYLEIGDHNRIREACTIHRGTVQD-----RGITRIGNQNLLMV 114 >4MYB-A nrPDB Length = 261 Score = 33.7 bits (75), Expect = 0.15, Method: Composition-based stats. Identities = 24/140 (17%), Positives = 46/140 (32%), Gaps = 5/140 (3%) Query: 5 AVVMAVGGGSRMTDLTSSIPKPLLPVGN-KPLIWYPLNLLERVGFEEVIVVTTRDVQKAL 63 ++ A G G+RM IPK + N K ++ L + I V Sbjct: 6 VIIPAAGIGTRMQ---LDIPKQYYKLNNGKTILDNTLVKFIDNPLFDKIFVAIAASDNFW 62 Query: 64 CAEFKMKMKPDIVCIPDDADMGTAD-SLRYIYPKLKTDVLVLSCDLITDVALHEVVDLFR 122 +VC + + +L I + D + + V++ ++DL+ Sbjct: 63 NNSLYYNHDKIVVCNGGETRFNSVYNALNVIDERKNDDWVFVHDAARPCVSIDSIIDLYE 122 Query: 123 AYDASLAMLMRKGQDSIEPV 142 +S + + E V Sbjct: 123 QTKSSHSQAGILAVRAYETV 142 >3Q1X-A nrPDB Length = 313 Score = 33.7 bits (75), Expect = 0.17, Method: Composition-based stats. Identities = 21/87 (24%), Positives = 35/87 (40%), Gaps = 10/87 (11%) Query: 358 IGPETQIGEKSSIKRSV---IGSSCLIKDRVTITNCLLMNSVTV-EEGSNIQ-----GSV 408 I P I I V IG + +I + I + + ++ EEG I+ Sbjct: 166 IHPGASIKGHFFIDHGVGVVIGETAIIGEWCRIYQSVTLGAMHFQEEGGVIKRGTKRHPT 225 Query: 409 ICNNAVIEKGAD-IKDCLIGSGQRIEA 434 + + I GA + + ++GS RI A Sbjct: 226 VGDYVTIGTGAKVLGNIIVGSHVRIGA 252 >4E6U-A nrPDB Length = 265 Score = 33.3 bits (74), Expect = 0.20, Method: Composition-based stats. Identities = 23/140 (16%), Positives = 45/140 (32%), Gaps = 29/140 (20%) Query: 340 VHSSAQIVSKHLVGVDSLIGPETQIGEKSSIKRSV-------IGSS------CLIKDRV- 385 + SA I S +G +IGP+ IG + + V IG + + + Sbjct: 16 IDPSAVIASDVQIGPYCIIGPQVTIGAGTKLHSHVVVGGFTRIGQNNEIFQFASVGEVCQ 75 Query: 386 --TITNCLLM----NSVTVEEGSNIQGSVICNNA--VIEKGADI-------KDCLIGSGQ 430 N+ + E ++ + +NA I + DC++G Sbjct: 76 DLKYKGEETWLEIGNNNLIREHCSLHRGTVQDNALTKIGSHNLLMVNTHIAHDCIVGDHN 135 Query: 431 RIEAKAKRVNEVIVGNDQLM 450 V +G+ ++ Sbjct: 136 IFANNVGVAGHVHIGDHVIV 155 >2Y6P-A nrPDB Length = 234 Score = 32.5 bits (72), Expect = 0.37, Method: Composition-based stats. Identities = 17/94 (18%), Positives = 39/94 (41%), Gaps = 9/94 (9%) Query: 1 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQ 60 M ++ A G +R+ + KPL + KPLI + + L + G ++ + V+ Sbjct: 1 MRRAVIIPARLGSTRLKE------KPLKNLLGKPLIRWVVEGLVKTGERVILATDSERVK 54 Query: 61 KALCAEFKMKMKPDIVCIPDDADMGTADSLRYIY 94 + + ++ + P + D + +R + Sbjct: 55 EVVEDLCEVFLTPSDLPSGSDRVL---YVVRDLD 85 >5NW4-h nrPDB Length = 222 Score = 32.1 bits (71), Expect = 0.46, Method: Composition-based stats. Identities = 31/157 (19%), Positives = 50/157 (31%), Gaps = 19/157 (12%) Query: 280 ACWNACRGDRWEDLSRSQVRCYVHIMKEGLCSRVSTLGLYME-ANRQVPKLLSALCPEEP 338 + WN DR R+ C + E L + Y+E A+ S LC + Sbjct: 16 SVWNRILTDRLTGFDRNG-SCEELVTME-LGELLYNKSEYIETASGNKVSRQSVLCGSQN 73 Query: 339 PVHSSAQIVSKHLV----GVDSLIGPETQIGEKSSIK-------RSVIGSSCLIKDRVTI 387 V + IV + + +G + +S I+ + V I D V Sbjct: 74 IVLNGKTIVMNDCIIRGDLANVRVGRHCVVKSRSVIRPPFKKFSKGVAFFPLHIGDHV-- 131 Query: 388 TNCLLMNSVTVEEGSNIQGSVICNNAVIEKGADIKDC 424 + V + N VI + +KDC Sbjct: 132 ---FIEEDCVVNAAQIGSYVHVGKNCVIGRRCVLKDC 165 Score = 31.7 bits (70), Expect = 0.63, Method: Composition-based stats. Identities = 13/95 (13%), Positives = 28/95 (29%), Gaps = 6/95 (6%) Query: 325 QVPKLLSALCPEEPPVHSSAQIVSKHLVGVDSLIGPETQIGEKSSIKRSVIGSSCLIKDR 384 V K S + P H +G I + + +G +C+I R Sbjct: 101 CVVKSRSVIRPPFKKFSKGVAFFPLH-IGDHVFIEEDCVVNAAQIGSYVHVGKNCVIGRR 159 Query: 385 VTITNCLLMNSVTVEEGSNIQGSVICNNAVIEKGA 419 + +C + + + + + + G Sbjct: 160 CVLKDC-----CKILDNTVLPPETVVPPFTVFSGC 189 >5DEP-A nrPDB Length = 258 Score = 31.7 bits (70), Expect = 0.62, Method: Composition-based stats. Identities = 28/147 (19%), Positives = 47/147 (31%), Gaps = 46/147 (31%) Query: 340 VHSSAQIVSKHLVGVDSLIGPETQIGEKSSIK---------------------------- 371 + + Q+ +VG + IG T IG +K Sbjct: 16 LAADVQVGPWSIVGAEVEIGEGTVIGPHVVLKGPTKIGKHNRIYQFSSVGEDTPDLKYKG 75 Query: 372 ---RSVIGSSCLIKDRVTI--------------TNCLLMNSVTVEEGSNIQ-GSVICNNA 413 R VIG +I++ VTI + L+M + S I ++ NN Sbjct: 76 EPTRLVIGDHNVIREGVTIHRGTVQDRAETTIGDHNLIMAYAHIGHDSVIGNHCILVNNT 135 Query: 414 VIEKGADIKDCLIGSGQRIEAKAKRVN 440 + + D I SG + + R+ Sbjct: 136 ALAGHVHVDDWAILSGYTLVHQYCRIG 162 >6F1T-V nrPDB Length = 182 Score = 31.4 bits (69), Expect = 0.77, Method: Composition-based stats. Identities = 13/95 (13%), Positives = 28/95 (29%), Gaps = 6/95 (6%) Query: 325 QVPKLLSALCPEEPPVHSSAQIVSKHLVGVDSLIGPETQIGEKSSIKRSVIGSSCLIKDR 384 V K S + P H +G I + + +G +C+I R Sbjct: 61 CVVKSRSVIRPPFKKFSKGVAFFPLH-IGDHVFIEEDCVVNAAQIGSYVHVGKNCVIGRR 119 Query: 385 VTITNCLLMNSVTVEEGSNIQGSVICNNAVIEKGA 419 + +C + + + + + + G Sbjct: 120 CVLKDC-----CKILDNTVLPPETVVPPFTVFSGC 149 Score = 31.0 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 14/93 (15%), Positives = 30/93 (32%), Gaps = 23/93 (24%) Query: 355 DSLIGPETQIGEKSSI----KRSVIGSSCLIKDRVTI-------TNCLLMNSVTVEEGSN 403 + ++ +T + I +G C++K R I + + + + + Sbjct: 33 NIVLNGKTIVMNDCIIRGDLANVRVGRHCVVKSRSVIRPPFKKFSKGVAFFPLHIGDHVF 92 Query: 404 IQGSVICNNAVIEK------------GADIKDC 424 I+ + N A I +KDC Sbjct: 93 IEEDCVVNAAQIGSYVHVGKNCVIGRRCVLKDC 125 >4XWI-A nrPDB Length = 262 Score = 31.0 bits (68), Expect = 1.0, Method: Composition-based stats. Identities = 25/122 (20%), Positives = 47/122 (38%), Gaps = 15/122 (12%) Query: 2 EFQAVVMAVGGGSRMTDLTSSIP-KPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQ 60 F V+ A +R+ P KPL + +P+I N + V+V T + Sbjct: 12 AFTVVIPARYASTRL-------PGKPLQDIAGQPMIQRVWNQARKSAASRVVVATDDERI 64 Query: 61 KALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPK--LKTDVLVLSCDLITDVALHEVV 118 A C F + + + + GT D L + + L +D +V++ + ++ Sbjct: 65 LAACQGFG----AEALLTRAEHNSGT-DRLEEVASRLGLASDAIVVNVQGDEPLIPPALI 119 Query: 119 DL 120 D Sbjct: 120 DQ 121 >3RH2-A nrPDB Length = 212 Score = 30.6 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 16/135 (11%), Positives = 36/135 (26%), Gaps = 1/135 (0%) Query: 175 DLDEELVIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYLVR 234 D+ + + +H T + AHL + I + + Sbjct: 4 TRDKIIQASLELFNEHGERTITTNHIAAHLDISPGNLYYHFRNKEDIIRCIFDQYEQHLL 63 Query: 235 KQFSSASSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWEDLS 294 F + Q+ E ++ + F+ LA D + + Sbjct: 64 LGFKPYADQKVDLELLMSYFDAMFYTMWQFRFMYANLADILARDDTLKARYL-KVQQAVL 122 Query: 295 RSQVRCYVHIMKEGL 309 + + K+G+ Sbjct: 123 EQSIAVLNQLKKDGI 137 >1J2Z-A nrPDB Length = 270 Score = 29.8 bits (65), Expect = 2.4, Method: Composition-based stats. Identities = 19/100 (19%), Positives = 39/100 (39%), Gaps = 16/100 (16%) Query: 352 VGVDSLIGPETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEGSNIQ-GSVIC 410 + ++I P+ +I + IG C+I D V + V + +Q + + Sbjct: 4 IAKTAIISPKAEINKGVE-----IGEFCVIGDGVKLD-----EGVKLHNNVTLQGHTFVG 53 Query: 411 NNAVIEKGADIKDCLIGSGQRIEAKAKRVNEVIVGNDQLM 450 N I ++G+ + +E+I+G D L+ Sbjct: 54 KNTEI-----FPFAVLGTQPQDLKYKGEYSELIIGEDNLI 88 >5FV4-A nrPDB Length = 544 Score = 29.4 bits (64), Expect = 3.1, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 21/72 (29%), Gaps = 5/72 (6%) Query: 70 KMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEVVDLFRAYDASLA 129 + D GT D ++ K L L D++ V V R A Sbjct: 372 IPEELTPVATDKYLGGTDDPVKK-----KDLFLDLMGDVVFGVPSVTVARQHRDAGAPTY 426 Query: 130 MLMRKGQDSIEP 141 M + + S Sbjct: 427 MYEFQYRPSFSS 438 >3OH0-A nrPDB Length = 641 Score = 28.7 bits (62), Expect = 5.3, Method: Composition-based stats. Identities = 15/57 (26%), Positives = 28/57 (49%), Gaps = 2/57 (3%) Query: 6 VVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEE--VIVVTTRDVQ 60 V++A G G R+ + + P+ N + Y L +RVG +E +++T+ D Sbjct: 118 VLVAGGLGERLGYSSIKVSLPVETATNTTYLAYYLRWAQRVGGKEVPFVIMTSDDTH 174 >4R36-A nrPDB Length = 275 Score = 28.3 bits (61), Expect = 6.6, Method: Composition-based stats. Identities = 9/75 (12%), Positives = 27/75 (36%), Gaps = 1/75 (1%) Query: 322 ANRQVPKLLSALCPEEPPVHSSAQIVSKHLVGVDSLIGPETQIGEKSSI-KRSVIGSSCL 380 NR + + + L+G ++G T++ + I ++I ++ L Sbjct: 112 INRGTAAKGRTIVGNNNLLMEGVHVAHDALIGNGCIVGNSTKMAGEIIIDDNAIISANVL 171 Query: 381 IKDRVTITNCLLMNS 395 + + +++ Sbjct: 172 MHQFCRVGGYVMIQG 186 >1KK6-A nrPDB Length = 209 Score = 28.3 bits (61), Expect = 6.7, Method: Composition-based stats. Identities = 10/41 (24%), Positives = 21/41 (51%), Gaps = 1/41 (2%) Query: 336 EEPPVHSSAQIVSKHLVGVDSLIGPETQIGEKSSI-KRSVI 375 ++ P+ I + +G D +I P +IG+ + + SV+ Sbjct: 106 DQLPIKGDTIIGNDVWIGKDVVIMPGVKIGDGAIVAANSVV 146 >5BN5-A nrPDB Length = 570 Score = 27.9 bits (60), Expect = 8.7, Method: Composition-based stats. Identities = 19/99 (19%), Positives = 39/99 (39%), Gaps = 13/99 (13%) Query: 6 VVMAVGGGSRMTDLTSSI---PKPLLPVGNKPLIWYPLNLL----ERVGFEEVIVVTTRD 58 +V+ +G G R ++T + PK P KPL++ + + + E + Sbjct: 244 IVIYIGCGERGNEMTEVLEEFPKLKDPKTGKPLMYRTILIANTSNMPIAAREASIYLGAT 303 Query: 59 VQKALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKL 97 + + + V + D+ A++LR I +L Sbjct: 304 IGEYFRDQGY------SVVVNADSTSRWAEALREISSRL 336 >3K4E-A nrPDB Length = 369 Score = 27.9 bits (60), Expect = 9.3, Method: Composition-based stats. Identities = 28/195 (14%), Positives = 78/195 (40%), Gaps = 20/195 (10%) Query: 74 DIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEVVDLFRAYDASLAMLMR 133 I + A I+ +++ D + LS D+ + + + + + L+ Sbjct: 42 GSRFIQRELATSPASEKEVIFNEIRDDAIELSNDVFGNYVIQKFFEFGSKIQKNT--LVD 99 Query: 134 KGQDSIEPVPGQKGKKKAVEQR-DFIGVDSTGKRLLFMANEADLDEELVIKGSILQK--- 189 + + +++ + Q + +++ ++I + + +L +++ + ++QK Sbjct: 100 QFKGNMKQLSLQMYACRVIQKALEYIDSNQRIELVLELSDSVLQMIKDQNGNHVIQKAIE 159 Query: 190 ---HPRIRFHTGLVDAHLYCLKKY-----IVDFLMENGSITSIRS------ELIPYLVRK 235 ++ F + H+Y L + ++ L+E GS S + IPYL++ Sbjct: 160 TIPIEKLPFILSSLTGHIYHLSTHSYGCRVIQRLLEFGSSEDQESILNELKDFIPYLIQD 219 Query: 236 QFSSASSQQGQEEKE 250 Q+ + Q ++ + Sbjct: 220 QYGNYVIQYVLQQDQ 234 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.313 0.119 0.269 Lambda K H 0.267 0.0363 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,667,054 Number of Sequences: 36641 Number of extensions: 444641 Number of successful extensions: 1610 Number of sequences better than 10.0: 104 Number of HSP's better than 10.0 without gapping: 102 Number of HSP's successfully gapped in prelim test: 60 Number of HSP's that attempted gapping in prelim test: 1261 Number of HSP's gapped (non-prelim): 239 length of query: 452 length of database: 10,336,785 effective HSP length: 100 effective length of query: 352 effective length of database: 6,672,685 effective search space: 2348785120 effective search space used: 2348785120 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 60 (27.9 bits)