BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9NQW7 (623 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3CTZ-A nrPDB 1291 0.0 4S2R-P nrPDB 467 e-132 5JR6-A nrPDB 307 1e-83 2ZSG-A nrPDB 96 4e-20 4RGZ-A nrPDB 91 1e-18 3Q6D-A nrPDB 89 5e-18 5CNX-A nrPDB 84 2e-16 1PV9-A nrPDB 82 5e-16 1WY2-A nrPDB 81 1e-15 4ZNG-C nrPDB 74 2e-13 3IG4-A nrPDB 63 5e-10 2BWY-A nrPDB 54 2e-07 4PV4-A nrPDB 49 6e-06 5X49-A nrPDB 49 8e-06 5MC5-A nrPDB 45 6e-05 5WZE-A nrPDB 45 8e-05 4ZWP-A nrPDB 43 3e-04 6A9U-A nrPDB 41 0.001 3L7G-A nrPDB 41 0.002 4QR8-A nrPDB 38 0.013 3RVA-A nrPDB 34 0.21 5JOZ-A nrPDB 30 2.4 5LYW-A nrPDB 30 2.5 1QZY-A nrPDB 30 4.6 5THX-A nrPDB 30 4.6 5CE6-A nrPDB 29 4.9 5HGQ-A nrPDB 29 5.4 5EJK-A nrPDB 29 7.3 4FW1-A nrPDB 29 7.7 >3CTZ-A nrPDB Length = 623 Score = 1291 bits (3342), Expect = 0.0, Method: Compositional matrix adjust. Identities = 620/623 (99%), Positives = 620/623 (99%) Query: 1 MPPKVTSELLRQLRQAMRNSEYVTEPIQAYIIPSGDAHQSEYIAPCDCRRAFVSGFDGSA 60 MPPKVTSELLRQLRQAMRNSEYVTEPIQAYIIPSGDAHQSEYIAPCDCRRAFVSGFDGSA Sbjct: 1 MPPKVTSELLRQLRQAMRNSEYVTEPIQAYIIPSGDAHQSEYIAPCDCRRAFVSGFDGSA 60 Query: 61 GTAIITEEHAAMWTDGRYFLQAAKQMDSNWTLMKMGLKDTPTQEDWLVSVLPEGSRVGVD 120 GTAIITEEHAAMWTDGRYFLQAAKQMDSNWTLMKMGLKDTPTQEDWLVSVLPEGSRVGVD Sbjct: 61 GTAIITEEHAAMWTDGRYFLQAAKQMDSNWTLMKMGLKDTPTQEDWLVSVLPEGSRVGVD 120 Query: 121 PLIIPTDYWKKMAKVLRSAGHHLIPVKENLVDKIWTDRPERPCKPLLTLGLDYTGISWKD 180 PLIIPTDYWKKMAKVLRSAGHHLIPVKENLVDKIWTDRPERPCKPLLTLGLDYTGISWKD Sbjct: 121 PLIIPTDYWKKMAKVLRSAGHHLIPVKENLVDKIWTDRPERPCKPLLTLGLDYTGISWKD 180 Query: 181 KVADLRLKMAERNVMWFVVTALDEIAWLFNLRGSDVEHNPVFFSYAIIGLETIMLFIDGD 240 KVADLRLKMAERNVMWFVVTALDEIAWLFNLRGSDVEHNPVFFSYAIIGLETIMLFIDGD Sbjct: 181 KVADLRLKMAERNVMWFVVTALDEIAWLFNLRGSDVEHNPVFFSYAIIGLETIMLFIDGD 240 Query: 241 RIDAPSVKEHLLLDLGLEAEYRIQVHPYKSILSELKALCADLSPREKVWVSDKASYAVSE 300 RIDAPSVKEHLLLDLGLEAEYRIQVHPYKSILSELKALCADLSPREKVWVSDKASYAVSE Sbjct: 241 RIDAPSVKEHLLLDLGLEAEYRIQVHPYKSILSELKALCADLSPREKVWVSDKASYAVSE 300 Query: 301 TIPKDHRCCMPYTPICIAKAVKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGGVTEI 360 TIPKDHRCCMPYTPICIAKAVKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGGVTEI Sbjct: 301 TIPKDHRCCMPYTPICIAKAVKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGGVTEI 360 Query: 361 SAADKAEEFRRQQADFVDLSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQY 420 SAADKAEEFRRQQADFVDLSFPTISSTGP GAIIHYAPVPETNRTLSLDEVYLIDSGAQY Sbjct: 361 SAADKAEEFRRQQADFVDLSFPTISSTGPTGAIIHYAPVPETNRTLSLDEVYLIDSGAQY 420 Query: 421 KDGTTDVTRTMHFGTPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSALWDSG 480 KDGTTDVTRTMHF TPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSALWDSG Sbjct: 421 KDGTTDVTRTMHFETPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSALWDSG 480 Query: 481 LDYLHGTGHGVGSFLNVHEGPCGISYKTFSDEPLEAGMIVTDEPGYYEDGAFGIRIENVV 540 LDYLHGTGHGVGSFLNVHEGPCGISYKTFSDEPLEAGMIVTDEPGYYEDGAFGIRIENVV Sbjct: 481 LDYLHGTGHGVGSFLNVHEGPCGISYKTFSDEPLEAGMIVTDEPGYYEDGAFGIRIENVV 540 Query: 541 LVVPVKTKYNFNNRGSLTFEPLTLVPIQTKMIDVDSLTDKECDWLNNYHLTCRDVIGKEL 600 LVVPVKTKYNFNNRGSLT EPLTLVPIQTKMIDVDSLTDKECDWLNNYHLTCRDVIGKEL Sbjct: 541 LVVPVKTKYNFNNRGSLTLEPLTLVPIQTKMIDVDSLTDKECDWLNNYHLTCRDVIGKEL 600 Query: 601 QKQGRQEALEWLIRETQPISKQH 623 QKQGRQEALEWLIRETQPISKQH Sbjct: 601 QKQGRQEALEWLIRETQPISKQH 623 >4S2R-P nrPDB Length = 639 Score = 467 bits (1202), Expect = e-132, Method: Compositional matrix adjust. Identities = 262/628 (41%), Positives = 374/628 (59%), Gaps = 32/628 (5%) Query: 8 ELLRQLRQAMRNSEYV-----TEPIQAYIIPSGDAHQSEYIAPCDCRRAFVSGFDGSAGT 62 E L +LR ++ +SE V ++P+ AY++PS DAH SEY+A D R F+SGF GS Sbjct: 28 EKLAKLR-SLFHSERVLALTSSKPMVAYLLPSTDAHHSEYLADYDFRVKFLSGFSGSNAY 86 Query: 63 AIITEEHAAMWTDGRYFLQAAKQMDSN-WTLMKMGLKDTPTQEDWLVSVLPEGSRVGVDP 121 ++T+ A +WTDGRYF QA Q+DSN W LMK G D+ T DWLV L GS +G DP Sbjct: 87 VVVTDREALLWTDGRYFTQAGNQLDSNSWKLMKQGQPDSITVVDWLVRELERGSVIGFDP 146 Query: 122 LIIPTDYWKKMAKVLRSAGHHLIPVKENLVDKIWTDRPERPCKPLLTLGLDYTGISWKDK 181 + D K K L++AG + + NLVD+ WTDRP +P++ L ++ TG++ K Sbjct: 147 TLSTFDAGSKTFKRLKAAGLQPVSIPGNLVDEFWTDRPRLAGEPVVVLDVEDTGLTTSKK 206 Query: 182 VADLRLKMAERNVMWFVVTALDEIAWLFNLRGSDVEHNPVFFSYAIIGLETIMLFIDGDR 241 V +LR K+ ++ V T LD++ WL N+RGSD+ +NP+ +SY + + I +FID ++ Sbjct: 207 VENLREKLKQKKCDAAVFTLLDDVMWLLNIRGSDIPYNPLAYSYLFVAMREIHVFIDNEK 266 Query: 242 IDAPSVKEHLLLDLGLEAEYRIQVHPYKSILS----ELKALCADLSPREKVWVSDKASYA 297 +D S + H + + +HPY + S LKA A P V+++ + +YA Sbjct: 267 LDEKS-RAHF-------HKSNVSIHPYGEVYSWISNWLKAKEASKEPH-MVYLTPETNYA 317 Query: 298 VSETIPKDHRCCMPYTPICIAKAVKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGG- 356 + I +++ + + + AKA KN E +GMR +H++D+ AL E WLEKE+ G Sbjct: 318 IGSIIGEEN-SMVDTSLVQTAKATKNDHEMQGMRNSHLRDSAALVEFLCWLEKELLSGKR 376 Query: 357 VTEISAADKAEEFRRQQADFVDLSFPTISSTGPNGAIIHYAPVPET-NRTLSLDEVYLID 415 TEI ADK + R Q +V LSF TIS+ G + A+ HY P+ E+ NR + ++V+L+D Sbjct: 377 YTEIELADKIDHLRSLQDKYVTLSFDTISAVGDHAALPHYKPLGESGNRKAAANQVFLLD 436 Query: 416 SGAQYKDGTTDVTRTMHFGTPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSA 475 SGA Y DGTTDVTRT+ + P T VLKGHI ++ A FP G G LD+ R A Sbjct: 437 SGAHYGDGTTDVTRTVWYTNPPKEFILHNTLVLKGHINLARAKFPDGIYGSRLDTLTRDA 496 Query: 476 LWDSGLDYLHGTGHGVGSFLNVHEGPCGISYKTF-SDEPLEAGMIVTDEPGYYEDGAFGI 534 LW GLD+ HGTGHGVG +LNVHEGP GI +++ + L A ++T EPG+Y +GI Sbjct: 497 LWKLGLDFEHGTGHGVGHYLNVHEGPIGIGHRSVPTGGELHASQVLTIEPGFYAKEKYGI 556 Query: 535 RIEN---VVLVVPVKTKYNFNNRGSLTFEPLTLVPIQTKMIDVDSLTDKECDWLNNYHLT 591 RIEN V V + NF LTF+ LTLVPIQT ++D L ++E +WLN YH Sbjct: 557 RIENCYETVEAVVMSKAQNF-----LTFKSLTLVPIQTSIVDKSLLIEEEINWLNQYHAR 611 Query: 592 CRDVIGKELQKQGRQEALEWLIRETQPI 619 +G+ LQK+G+ + L+WL +PI Sbjct: 612 VLKEVGEHLQKRGKTDELKWLAEACKPI 639 >5JR6-A nrPDB Length = 664 Score = 307 bits (786), Expect = 1e-83, Method: Compositional matrix adjust. Identities = 208/659 (31%), Positives = 334/659 (50%), Gaps = 69/659 (10%) Query: 10 LRQLRQAMRNSEYVTEPIQAYIIPSGDAHQSEYIAPCDCRRAFVSGFDGSAGTAIITEEH 69 L +LR M+ ++ I YI+ + D H SE I D + ++ + G+ G I+T++ Sbjct: 17 LEELRTIMKKNK-----IDVYILINSDEHNSEIINEKDKKIVKITNYSGADGILIVTKDK 71 Query: 70 AAMWTDGRYFLQAAKQMDSNWTLMKMGLKDTPTQEDWLVSVLPEGSRVGVDPLIIPTDYW 129 ++ + Y LQA ++D N +++ D + +S L E + + D ++ Sbjct: 72 PILYVNALYELQAMNELDQNLFTLRISRIDNRDEIFETISSL-EFNTIAFDGKNTSVVFY 130 Query: 130 KKMAKVLRSAGHHLIPVKENLVDKIWTDRPERPCKPLLTLGL------------------ 171 +K+ K L +A V++ + + + D ++ + +L + Sbjct: 131 EKLRKALLNAYPKKKIVEKIIYNNNFDDVNKKDDENVLNFLVLEKSLVEIKDYPVNNKTL 190 Query: 172 -----DYTGISWKDKVADLR--LKMAERNVMWFVVTALDEIAWLFNLRGSDVEHNPVFFS 224 Y G +K+ L+ L +NV +++ LDEIA+L NLRG D +++P+F+S Sbjct: 191 YIHDRKYNGACAGEKIDKLKQSLMYDIKNVDNLLLSELDEIAYLLNLRGYDYQYSPLFYS 250 Query: 225 YAIIGLE-------TIMLFIDGDRIDAPSVKEHLLLDLGLEAEYRIQVHPYKSILSELKA 277 Y + + I+ F + A VK LL++ ++ V Y+ I+ L+ Sbjct: 251 YLLFQFDREEQDFSKIVFFTTVKNLPA-DVKN--LLEIN-----KVIVKEYEEIVPYLRD 302 Query: 278 LCADLSPREKVWVSDKASYAVSET---------IPKDHRCCMPYTPICIAKAVKNSAESE 328 + P+ D Y +S + + + +P+ KAVKN E + Sbjct: 303 VVIPSIPKHNDDNPDFKKYDISLSPYINLMIYKLFDRKNVLLQNSPVVKMKAVKNDVEID 362 Query: 329 GMRRAHIKDAVALCELFNWLEKEVPKGGV---TEISAADKAEEFRRQQADFVDLSFPTIS 385 M++AHI D +AL + F+W E++ + TE+S K + FR + +F+ SF TIS Sbjct: 363 NMKQAHILDGLALLQFFHWCEQKRKTKELFNETEMSLRHKVDYFRSTKKNFIFPSFSTIS 422 Query: 386 STGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDVTRTMHFGTPTAYEKECFT 445 ++GPN A+IHY +TN T+ +YL+DSG QY GTTDVTRT HFG PTA EK +T Sbjct: 423 ASGPNAAVIHYECTDKTNATIK-PAIYLLDSGGQYLHGTTDVTRTTHFGEPTAEEKRIYT 481 Query: 446 YVLKGHIAVSAAVFPTGTKGHLLDSFARSALWDSGLDYLHGTGHGVGSFLNVHEGPCGIS 505 VLKGH+ + +F + T LD AR L+++ +DY HGTGHGVG LNVHEG C I Sbjct: 482 LVLKGHLRLRKVIFASYTNSSALDFIARENLFNNFMDYNHGTGHGVGLTLNVHEGGCSIG 541 Query: 506 YKTFSDEPLEAGMIVTDEPGYYEDGAFGIRIENVVLVVPVKTKYNFNNRGSLTFEPLTLV 565 PL+ M++++EPGYY FG+RIEN+ V+ +K + L+F+ LT+ Sbjct: 542 --PVGGAPLKKNMVLSNEPGYYMKDKFGVRIENMQYVI---SKEITDTTEYLSFDDLTMY 596 Query: 566 PIQTKMIDVDSLTDKECDWLNNYHLTCRDVIGKELQKQGRQEALE----WLIRETQPIS 620 P + K++D LT++E LN YH T R+ + L KQ QE E +LI T+PI+ Sbjct: 597 PYEKKLLDFSLLTNQEIKELNEYHTTIRNTL-LPLVKQSPQEYGESVEKYLIEITEPIA 654 >2ZSG-A nrPDB Length = 359 Score = 96.3 bits (238), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 77/227 (33%), Positives = 117/227 (51%), Gaps = 20/227 (8%) Query: 319 KAVKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGGVTEISAADKAE-EFRRQQADFV 377 + VK+ E E IK A+ + E + + G+TE A E R++ A+ V Sbjct: 131 RMVKDEGEIE-----KIKQAIEISERAFLETVQQIRAGMTEKEIAALLEYTMRKEGAEGV 185 Query: 378 DLSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDVTRTMHFGTPT 437 +F TI ++G A+ H +++ + +V +ID GA Y++ D+TR + G P+ Sbjct: 186 --AFDTIVASGCRSALPHGKA---SDKVVERGDVIVIDFGATYENYCADITRVVSIGEPS 240 Query: 438 AYEKECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSALWDSGLD--YLHGTGHGVGSFL 495 KE + VL+ + + G G LLDS AR + + G + H GHG+G L Sbjct: 241 DEVKEVHSIVLEAQ-ERALKIAKAGVTGKLLDSVAREFIREKGYGEFFGHSLGHGIG--L 297 Query: 496 NVHEGPCGISYKTFSDEPLEAGMIVTDEPGYYEDGAFGIRI-ENVVL 541 VHEGP IS++ +D PL ++ T EPG Y +G FGIRI E+VVL Sbjct: 298 EVHEGPA-ISFR--NDSPLPENVVFTVEPGIYLEGKFGIRIEEDVVL 341 Score = 32.7 bits (73), Expect = 0.53, Method: Compositional matrix adjust. Identities = 16/45 (35%), Positives = 24/45 (53%) Query: 52 FVSGFDGSAGTAIITEEHAAMWTDGRYFLQAAKQMDSNWTLMKMG 96 + SGF GS +I+E + TD RY +QA ++ D +K G Sbjct: 34 YFSGFTGSFSIILISENTRLLITDSRYTVQAKQETDFEVREVKGG 78 >4RGZ-A nrPDB Length = 367 Score = 91.3 bits (225), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 82/287 (28%), Positives = 139/287 (48%), Gaps = 24/287 (8%) Query: 266 HPYKSILSELKALCADLSPREKVWVSDKASYAVSETIPK--DHRCCMPYTP-ICIAKAVK 322 +PYK +++K + EK+ + D V D P +P I + +K Sbjct: 85 NPYKIFATKIKETFKE---GEKLLIDDTMPVGVFLKAKDIFDKYSLHPISPVISELREIK 141 Query: 323 NSAESEGMRRA-HIKDAVALCELFNWLEKEVPKGGVTEISAADKAEEFRRQQADFVDLSF 381 + E + ++A I D V + ++E ++ G +E A++ E + + D+SF Sbjct: 142 DKDEIKAHKKAAEIVDKV----FYRFIEGKLE--GKSERELANRIEYMIKNEFGADDVSF 195 Query: 382 PTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDVTRTMHFGTPTAYEK 441 I ++GPNGA H+ P ++R + +V + D GA+Y +DVTRT+ G P+ K Sbjct: 196 EPIVASGPNGANPHHRP---SHRKIRKGDVVIFDYGAKYLGYCSDVTRTVVVGPPSEEVK 252 Query: 442 ECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSAL--WDSGLDYLHGTGHGVGSFLNVHE 499 + + V + V G ++D+ AR + + G ++H TGHG+G ++VHE Sbjct: 253 KVYEIVKEAQETAVQKV-AEGIPAEVVDATARGIISKYGYGEYFIHRTGHGLG--IDVHE 309 Query: 500 GPCGISYKTFSDEPLEAGMIVTDEPGYYEDGAFGIRIENVVLVVPVK 546 P + + L+ GM+ T EPG Y G FG+RIE+ V +V K Sbjct: 310 EPY---ISPGNKKILKDGMVFTIEPGIYLQGKFGVRIEDDVALVDKK 353 >3Q6D-A nrPDB Length = 356 Score = 89.4 bits (220), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 63/189 (33%), Positives = 98/189 (51%), Gaps = 12/189 (6%) Query: 356 GVTEISAADKAEEFRRQQADFVDLSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLID 415 GV+EI +++ E F R+Q SF I ++G A+ H + + + + +D Sbjct: 160 GVSEIEVSNELEFFMRKQGA-TSSSFDIIVASGLRSALPHGVA---SEKVIETGDFVTLD 215 Query: 416 SGAQYKDGTTDVTRTMHFGTPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSA 475 GA YK +D+TRT+ G P+ KE + VL+ + + G G D+ R Sbjct: 216 FGAYYKGYCSDITRTIAVGEPSDKLKEIYNIVLEAQLRGVNGI-KAGLTGREADALTRDY 274 Query: 476 LWDSGLD--YLHGTGHGVGSFLNVHEGPCGISYKTFSDEPLEAGMIVTDEPGYYEDGAFG 533 + + G + H TGHG+G L +HE P G++++ SD LE GM VT EPG Y G G Sbjct: 275 ITEKGYGEYFGHSTGHGIG--LEIHEAP-GLAFR--SDTVLEPGMAVTVEPGIYIPGIGG 329 Query: 534 IRIENVVLV 542 +RIE+ ++V Sbjct: 330 VRIEDDIIV 338 Score = 35.4 bits (80), Expect = 0.065, Method: Compositional matrix adjust. Identities = 17/48 (35%), Positives = 27/48 (56%) Query: 50 RAFVSGFDGSAGTAIITEEHAAMWTDGRYFLQAAKQMDSNWTLMKMGL 97 R +++ F G+AG +I+++ A TD RY QA+KQ + GL Sbjct: 30 RRYMANFTGTAGVVLISKKRAQFITDFRYVEQASKQAVGYEIVQHAGL 77 >5CNX-A nrPDB Length = 361 Score = 84.0 bits (206), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 66/198 (33%), Positives = 102/198 (51%), Gaps = 17/198 (8%) Query: 354 KGGVTEISAADKAEEFRRQQADFVDLSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYL 413 + G++E A + E F RQQ SF TI ++G GA+ H +++ ++ E Sbjct: 155 QAGMSEREIAAELEWFMRQQGA-EKASFDTIVASGWRGALPHGKA---SDKIVAAGEFVT 210 Query: 414 IDSGAQYKDGTTDVTRTMHF-GTPTAYEK----ECFTYVLKGHIAVSAAVFPTGTKGHLL 468 +D GA Y+ +D+TRT+ G + E + VL+ +A +A+ P G + + Sbjct: 211 LDFGALYQGYCSDMTRTLLVNGEGVSAESHLLFNVYQIVLQAQLAAISAIRP-GVRCQQV 269 Query: 469 DSFARSALWDSGL-DYL-HGTGHGVGSFLNVHEGPCGISYKTFSDEPLEAGMIVTDEPGY 526 D AR + ++G DY H TGH +G + VHE P + L+ GM++T EPG Sbjct: 270 DDAARRVITEAGYGDYFGHNTGHAIG--IEVHEDP---RFSPRDTTTLQPGMLLTVEPGI 324 Query: 527 YEDGAFGIRIENVVLVVP 544 Y G G+RIE+VVLV P Sbjct: 325 YLPGQGGVRIEDVVLVTP 342 >1PV9-A nrPDB Length = 348 Score = 82.4 bits (202), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 55/165 (33%), Positives = 86/165 (52%), Gaps = 11/165 (6%) Query: 380 SFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDVTRTMHFGTPTAY 439 +F TI ++G A+ H +++ + ++ +ID GA Y +D+TRT+ G+P Sbjct: 177 AFDTIIASGHRSALPHGVA---SDKRIERGDLVVIDLGALYNHYNSDITRTIVVGSPNEK 233 Query: 440 EKECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSALWDSGL-DY-LHGTGHGVGSFLNV 497 ++E + VL+ A P G LDS AR + + G DY +H GHGVG L + Sbjct: 234 QREIYEIVLEAQKRAVEAAKP-GMTAKELDSIAREIIKEYGYGDYFIHSLGHGVG--LEI 290 Query: 498 HEGPCGISYKTFSDEPLEAGMIVTDEPGYYEDGAFGIRIENVVLV 542 HE P + + L+ GM++T EPG Y G+RIE+ VL+ Sbjct: 291 HEWP---RISQYDETVLKEGMVITIEPGIYIPKLGGVRIEDTVLI 332 >1WY2-A nrPDB Length = 351 Score = 81.3 bits (199), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 53/165 (32%), Positives = 85/165 (51%), Gaps = 11/165 (6%) Query: 380 SFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDVTRTMHFGTPTAY 439 +F TI ++G A+ H +++ + ++ +ID GA Y+ +D+TRT+ G+P Sbjct: 180 AFDTIIASGYRSALPHGVA---SDKRIERGDLVVIDLGALYQHYNSDITRTIVVGSPNEK 236 Query: 440 EKECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSALWDSGLD--YLHGTGHGVGSFLNV 497 +KE + VL+ + P G LDS AR+ + + G + H GHGVG L V Sbjct: 237 QKEIYEIVLEAQKKAVESAKP-GITAKELDSIARNIIAEYGYGEYFNHSLGHGVG--LEV 293 Query: 498 HEGPCGISYKTFSDEPLEAGMIVTDEPGYYEDGAFGIRIENVVLV 542 HE P + + L GM++T EPG Y G+RIE+ +L+ Sbjct: 294 HEWP---RVSQYDETVLREGMVITIEPGIYIPKIGGVRIEDTILI 335 >4ZNG-C nrPDB Length = 362 Score = 73.6 bits (179), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 57/191 (29%), Positives = 90/191 (47%), Gaps = 12/191 (6%) Query: 354 KGGVTEISAADKAEEFRRQQADFVDLSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYL 413 + GVTE K E + ++ +SF T+ +G A H AP N + +++ L Sbjct: 164 RNGVTESDIVAKIE-YEMKRMGVPQMSFDTLVLSGARAANPHGAP---ENVEIQENKLLL 219 Query: 414 IDSGAQYKDGTTDVTRTMHFGTPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHLLDSFAR 473 D G +D TRT+ G P ++ E V + A + P G H +D+ AR Sbjct: 220 FDLGVMSGGYASDATRTIAIGQPNDFDAEIHKIVKEAQQAAMDFIKP-GVTAHEVDAVAR 278 Query: 474 SALWDSGLD--YLHGTGHGVGSFLNVHEGPCGISYKTFSDEPLEAGMIVTDEPGYYEDGA 531 + +G + H GHG+G ++VHE P S +D ++ GM ++EPG Y G Sbjct: 279 DLITKAGYGEYFNHRLGHGIG--MDVHEYP---SIVAGNDLVIQEGMCFSNEPGIYIPGK 333 Query: 532 FGIRIENVVLV 542 G+RIE+ + V Sbjct: 334 VGVRIEDCLYV 344 >3IG4-A nrPDB Length = 427 Score = 62.8 bits (151), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 63/216 (29%), Positives = 98/216 (45%), Gaps = 37/216 (17%) Query: 352 VPKGGVTEI---SAADKAEEFRRQQADFVDLS-------FPTISSTGPNGAIIHYAPVPE 401 V K G+ + + AD E Q DF S F TI ++G N ++HY + Sbjct: 186 VTKDGIYNVLKHAKADMMEYELEAQFDFTLKSSGIKHHAFNTILASGKNATVLHY---ED 242 Query: 402 TNRTLSLDEVYLIDSGAQYKDGTTDVTRTM-HFGTPTAYEKECFTYVLKGHIAVSAAVFP 460 + + ++ L+D GAQ D++ T GT ++ +K+ + VL + + P Sbjct: 243 NDAQIQNGDLVLLDLGAQKDYYNADISYTFPANGTFSSRQKQIYNIVLNALKETTEIIKP 302 Query: 461 TGTKGHLLDSFARSALWDS----GL---------DYLHGTGHGVGSFLNVHEGPCGISYK 507 G K L+ A+ L + GL Y HG H +G L+ H+ Sbjct: 303 -GLKFAALNEHAKKVLAEGCKAVGLIQEDEELSKYYYHGVSHFLG--LDTHD------VG 353 Query: 508 TFSDEPLEAGMIVTDEPGYY-EDGAFGIRIENVVLV 542 T+ D LE GM++T EPG Y E+ + GIRIE+ +LV Sbjct: 354 TYKDRVLEEGMVITIEPGLYIEEESIGIRIEDDILV 389 >2BWY-A nrPDB Length = 440 Score = 53.9 bits (128), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 56/205 (27%), Positives = 91/205 (44%), Gaps = 41/205 (20%) Query: 368 EFRRQQADFVDLSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDV 427 EF R A + S+ TI +G NG I+HY E + ++ LID+G +YK D+ Sbjct: 218 EFNRHGARYP--SYNTIVGSGENGCILHYT---ENECEMRDGDLVLIDAGCEYKGYAGDI 272 Query: 428 TRTMHF-GTPTAYEKECFTYVLKGHIAVSAAVFPTGTK-----GH----LLDSFARSALW 477 TRT G T ++E + VL+ + S ++ GT G ++ + + Sbjct: 273 TRTFPVNGKFTQAQREIYDIVLES-LETSLRLYRPGTSILEVTGEVVRIMVSGLVKLGIL 331 Query: 478 DSGLD-----------YLHGTGHGVGSFLNVHEGPCGISYKTFSDEPLEAGMIVTDEPGY 526 +D ++HG H +G L+VH+ G+ Y LE GM++T PG Sbjct: 332 KGDVDELIAQNAHRPFFMHGLSHWLG--LDVHD--VGV-YGQDRSRILEPGMVLTVAPGL 386 Query: 527 Y---------EDGAFGIRIENVVLV 542 Y + GIRIE+ +++ Sbjct: 387 YIAPDAEVPEQYRGIGIRIEDDIVI 411 >4PV4-A nrPDB Length = 445 Score = 48.9 bits (115), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 59/209 (28%), Positives = 88/209 (42%), Gaps = 48/209 (22%) Query: 368 EFRRQQADFVDLSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDV 427 EF R A + ++ TI G NG I+HY E L ++ LID+G +Y+ D+ Sbjct: 216 EFTRHGARYP--AYNTIVGGGENGCILHYT---ENECELRDGDLVLIDAGCEYRGYAGDI 270 Query: 428 TRTMHF-GTPTAYEKECFTYVLKGHIAVSAAVFPTGT----------------------- 463 TRT G T ++ + VL I S +F GT Sbjct: 271 TRTFPVNGKFTPAQRAVYDIVLAA-INKSLTLFRPGTSIREVTEEVVRIMVVGLVELGIL 329 Query: 464 KGHLLDSFARSALWDSGLDYLHGTGHGVGSFLNVHE-GPCGISYKTFSDEPLEAGMIVTD 522 KG + A A ++HG H +G ++VH+ G G S + LE GM++T Sbjct: 330 KGDIEQLIAEQAHRPF---FMHGLSHWLG--MDVHDVGDYGSSDR---GRILEPGMVLTV 381 Query: 523 EPGYY---------EDGAFGIRIENVVLV 542 EPG Y + GIRIE+ +++ Sbjct: 382 EPGLYIAPDADVPPQYRGIGIRIEDDIVI 410 >5X49-A nrPDB Length = 456 Score = 48.5 bits (114), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 65/254 (25%), Positives = 105/254 (41%), Gaps = 47/254 (18%) Query: 319 KAVKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGGVTEISAADKAE-EFRRQQADFV 377 + +K+ AE E M+ A + A E K V E K E E R + AD Sbjct: 193 RLIKSPAEIERMQIAGKLTSQAFIETMF-----TSKAPVEEAFLYAKFEFECRARGADI- 246 Query: 378 DLSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDVTRTMHF-GTP 436 L++P + + G +HY + N+ + E+ L+D G + +D+TRT G Sbjct: 247 -LAYPPVVAGGNRSNTLHYV---KNNQLIKDGEMVLLDGGCESSCYVSDITRTWPVNGRF 302 Query: 437 TAYEKECFTYVLKGHIAVSAAVFPTGTKGH-----------------LLDSFARSALWDS 479 TA + E + VL+ A FP + + ++ + + + + Sbjct: 303 TAPQAELYEAVLEIQRDCLALCFPGTSLENIYSMMLTLIGQKLKDLGIMKNIKENNAFKA 362 Query: 480 GLDYL-HGTGHGVGSFLNVHEGPCGISYKTFSDEPLEAGMIVTDEPGYY--EDG------ 530 Y H GH +G ++VH+ P PL+ GM++T EPG Y ED Sbjct: 363 ARKYCPHHVGHYLG--MDVHDTP-----DMPRSLPLQPGMVITIEPGIYIPEDDKDAPEK 415 Query: 531 --AFGIRIENVVLV 542 G+RIE+ V+V Sbjct: 416 FRGLGVRIEDDVVV 429 >5MC5-A nrPDB Length = 478 Score = 45.4 bits (106), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 54/209 (25%), Positives = 85/209 (40%), Gaps = 41/209 (19%) Query: 354 KGGVTEISAADKAEEFRRQQADFVDLSFPTISSTGPNGAIIHYAPVPETN-RTLSLDEVY 412 K G+ E E + + S+ I +G N A++HY N RT+ ++ Sbjct: 209 KVGMKEYELESLFEHYCYSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDMC 268 Query: 413 LIDSGAQYKDGTTDVTRTM-HFGTPTAYEKECFTYVLKGHIAVSAAVFP---------TG 462 L D G +Y +D+T + G TA +K + VL+ AV A+ P Sbjct: 269 LFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRLA 328 Query: 463 TKGHLLDSFARSALWDSGLDYL-----------HGTGHGVGSFLNVHE---GPCGISYKT 508 + H L+ A + +D + HG GH +G ++VH+ P G+ Sbjct: 329 DRIH-LEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLG--IDVHDVGGYPEGVER-- 383 Query: 509 FSDEP----------LEAGMIVTDEPGYY 527 DEP L+ GM++T EPG Y Sbjct: 384 -IDEPGLRSLRTARHLQPGMVLTVEPGIY 411 >5WZE-A nrPDB Length = 452 Score = 45.4 bits (106), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 67/258 (25%), Positives = 111/258 (43%), Gaps = 60/258 (23%) Query: 319 KAVKNSAESEGMRRAHIKDAVALCE--LFNW-LEKEVPKGGVTEISAADKAEEFRRQQAD 375 K ++ +AE RAHI+ A+ +C LF + LE E+ EFR+ A Sbjct: 182 KVMRYAAEVSA--RAHIR-AMEVCRPGLFEYHLEAELEY-------------EFRKGGAK 225 Query: 376 FVDLSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDVTRTM-HFG 434 ++ +I + G N I+HY E + + ++ LID+G + +D+TRT G Sbjct: 226 MP--AYGSIVAAGRNACILHYR---ENDAAIKDGDLILIDAGCEIDCYASDITRTFPANG 280 Query: 435 TPTAYEKECFTYVLKGHIAVSAAVFP--------TGTKGHLLDSFARSALWDSGLD---- 482 + +K + VL+ ++A + P T + R L + +D Sbjct: 281 RFSPEQKAIYELVLEANMAAFDYIAPGRHWNEAHEATVRVITAGLVRLGLLEGDVDELIA 340 Query: 483 -------YLHGTGHGVGSFLNVHEGPCGISYKTFSD-EPLEAGMIVTDEPGYY------- 527 Y+H GH +G ++VH+ G Y+ + LE GM +T EPG Y Sbjct: 341 HEAYKAFYMHRAGHWLG--MDVHD--VG-EYRVGGEWRVLEPGMAMTVEPGIYIAPDNTT 395 Query: 528 ---EDGAFGIRIENVVLV 542 + G+RIE+ V+V Sbjct: 396 VAKKWRGIGVRIEDDVVV 413 >4ZWP-A nrPDB Length = 440 Score = 43.1 bits (100), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 55/203 (27%), Positives = 76/203 (37%), Gaps = 52/203 (25%) Query: 368 EFRRQQADFV-------DLSFPTISSTGPNGAIIHYAP----VPETNRTLSLDEVYLIDS 416 EF QQA + D F I + N AI+HY P T+R+ +LID+ Sbjct: 192 EFEIQQAYLLATQHSENDTPFGNIVALNENCAILHYTHFDRVAPATHRS------FLIDA 245 Query: 417 GAQYKDGTTDVTRTMHFGTPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHL-LDSFARSA 475 GA + D+TRT F + E + + IA+ + P G L LD R A Sbjct: 246 GANFNGYAADITRTYDFTGEGEF-AELVATMKQHQIALCNQLAPGKLYGELHLDCHQRVA 304 Query: 476 LWDSGLD------------------YLHGTGHGVGSFLNVHE-GPCGISYKTFSDEP--- 513 S + + HG GH +G L VH+ G + EP Sbjct: 305 QTLSDFNIVNLSADEIVAKGITSTFFPHGLGHHIG--LQVHDVGGFMADEQGAHQEPPEG 362 Query: 514 ---------LEAGMIVTDEPGYY 527 +EA + T EPG Y Sbjct: 363 HPFLRCTRKIEANQVFTIEPGLY 385 >6A9U-A nrPDB Length = 455 Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust. Identities = 46/186 (24%), Positives = 79/186 (42%), Gaps = 39/186 (20%) Query: 384 ISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDVTRTM-HFGTPTAYEKE 442 + +TG N IHY + + DE+ L+D+ D++RT + G T +++ Sbjct: 243 VVATGSNSLCIHYT---RNDDVMFDDEMVLVDAAGSLGGYCADISRTWPNSGKFTDAQRD 299 Query: 443 CFTYVLKGHIAVSAAVFPTGTKGHLLD-------SFARSALWDSGLD----------YLH 485 + VL ++ + + L + + L + G+D Y H Sbjct: 300 LYEAVL--NVQRDCIKLCKASNNYSLHDIHEKSITLMKQELKNLGIDKVSGWNVEKLYPH 357 Query: 486 GTGHGVGSFLNVHEGPCGISYKTFSDEPLEAGMIVTDEPGYY--EDGAF-------GIRI 536 GH +G L+VH+ P Y EPL+ G ++T EPG Y + +F GIRI Sbjct: 358 YIGHNLG--LDVHDVPKVSRY-----EPLKVGQVITIEPGLYIPNEESFPSYFRNVGIRI 410 Query: 537 ENVVLV 542 E+ + + Sbjct: 411 EDDIAI 416 >3L7G-A nrPDB Length = 517 Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust. Identities = 56/204 (27%), Positives = 78/204 (38%), Gaps = 54/204 (26%) Query: 368 EFRRQQADFV-------DLSFPTISSTGPNGAIIHYAP----VPETNRTLSLDEVYLIDS 416 EF QQA + D + I + N AI+HY P T+R+ +LID+ Sbjct: 192 EFEIQQAYLLATQHSENDNPYGNIVALNENCAILHYTHFDRVAPATHRS------FLIDA 245 Query: 417 GAQYKDGTTDVTRTMHFGTPTAYEKECFTYVLKGH-IAVSAAVFPTGTKGHL-LDSFARS 474 GA + D+TRT F + + T +K H IA+ + P G L LD R Sbjct: 246 GANFNGYAADITRTYDFTGEGEFAELVAT--MKQHQIALMNQLAPGKLYGELHLDCHQRV 303 Query: 475 ALWDSGLD------------------YLHGTGHGVGSFLNVHE-GPCGISYKTFSDEP-- 513 A S + + HG GH +G L VH+ G + EP Sbjct: 304 AQTLSDFNIVDLSADEIVAKGITSTFFPHGLGHHIG--LQVHDVGGFMADEQGAHQEPPE 361 Query: 514 ----------LEAGMIVTDEPGYY 527 +EA + T EPG Y Sbjct: 362 GHPFLRCTRKIEANQVFTIEPGLY 385 >4QR8-A nrPDB Length = 443 Score = 38.1 bits (87), Expect = 0.013, Method: Compositional matrix adjust. Identities = 52/228 (22%), Positives = 86/228 (37%), Gaps = 60/228 (26%) Query: 350 KEVPKGGVTEISAADKAEEFRRQQADF--------------VDLSFPTISSTGPNGAIIH 395 +E K V AA++A FR ++F D+ + I + + A++H Sbjct: 171 REAQKMAVNGHRAAEEA--FRSGMSEFDINIAYLTATGHRDTDVPYSNIVALNEHAAVLH 228 Query: 396 YAPV----PETNRTLSLDEVYLIDSGAQYKDGTTDVTRTMHFGTPTAY---------EKE 442 Y + PE R+ +L+D+GA+Y D+TRT + Y E+ Sbjct: 229 YTKLDHQAPEEMRS------FLLDAGAEYNGYAADLTRTWSAKSDNDYAQLVKDVNDEQL 282 Query: 443 CFTYVLKG-------HIAVSAAVFPTGTKGHLLDSFARSALWDSGLD---YLHGTGHGVG 492 +K HI + K ++ + A+ ++ L HG GH +G Sbjct: 283 ALIATMKAGVSYVDYHIQFHQRIAKLLRKHQIITDMSEEAMVENDLTGPFMPHGIGHPLG 342 Query: 493 SFLNVH------EGPCGISYKTFSDEP-------LEAGMIVTDEPGYY 527 L VH + G + P L+ GM++T EPG Y Sbjct: 343 --LQVHDVAGFMQDDSGTHLAAPAKYPYLRCTRILQPGMVLTIEPGIY 388 >3RVA-A nrPDB Length = 451 Score = 33.9 bits (76), Expect = 0.21, Method: Compositional matrix adjust. Identities = 58/233 (24%), Positives = 91/233 (39%), Gaps = 68/233 (29%) Query: 350 KEVPKGGVTEISAADKAEEFRRQQADF-VDLSFPTISSTGPN-------------GAIIH 395 +E K V AA++A FR +++F ++L++ S G N +I+H Sbjct: 169 REANKLAVAGHKAAEQA--FREGKSEFDINLAYAAASRQGDNDVPYTSIVALNEHASILH 226 Query: 396 YAP----VPETNRTLSLDEVYLIDSGAQYKDGTTDVTRTMHFGTPTAYEKECFTYVLKGH 451 Y P+ +R+ +LID+GA Y D+TRT + + F +++ Sbjct: 227 YMQCDTVAPKESRS------FLIDAGANYHGYAADITRT--YAQEGVHNSAMFRDLIQAV 278 Query: 452 IAVSAAVFPTGTKG------HLL--DSFARSALWDSGLDYL----------------HGT 487 V+ + + G HLL D A+ L D+G+ L HG Sbjct: 279 DKVTLTLVDSLKPGVAYTDIHLLAHDGIAQ-ILHDTGMVNLTPPEIVEMGITRTFFPHGI 337 Query: 488 GHGVGSFLNVHE------GPCGISYKTFSDEP-------LEAGMIVTDEPGYY 527 GH +G L VH+ G D P +EA + T EPG Y Sbjct: 338 GHFLG--LQVHDVGGLVNDDRGTPKPAPDDHPFLRCTRMVEARQVFTIEPGLY 388 >5JOZ-A nrPDB Length = 515 Score = 30.4 bits (67), Expect = 2.4, Method: Compositional matrix adjust. Identities = 31/115 (26%), Positives = 46/115 (40%), Gaps = 17/115 (14%) Query: 87 DSNWTLMKMGLKDTPTQEDWLVSVLPEGSRVGVDPLIIPTDYWKKMAKVLRSAGHHLIPV 146 D +W + +G++ + L G + P+ D W K+ K +L P Sbjct: 246 DGSWWAVCLGIRPVNGKYQHL------GRETFLAPVTWDADGWPKVGKDGVVQETYLFP- 298 Query: 147 KENLVDKIWTDRPERPCKPLLTLGLDYTGI--------SWKDKVADLRLKMAERN 193 NL +W ++P R TLGLD+T I S +K LRLK N Sbjct: 299 --NLPSHVWMEQPVRDDFDQETLGLDWTFIRNPAHSFWSLTEKPGSLRLKGTAIN 351 >5LYW-A nrPDB Length = 378 Score = 30.4 bits (67), Expect = 2.5, Method: Compositional matrix adjust. Identities = 24/84 (28%), Positives = 32/84 (38%), Gaps = 6/84 (7%) Query: 354 KGGVTEISAADKAEEFRR----QQADFVDLSFPTISSTGPNGAIIHYAPVPETNRTLSLD 409 K G+T I +K E+ R + L+FPT S N HY P L D Sbjct: 82 KPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSL--NNCAAHYTPNAGDTTVLQYD 139 Query: 410 EVYLIDSGAQYKDGTTDVTRTMHF 433 ++ ID G D T+ F Sbjct: 140 DICKIDFGTHISGRIIDCAFTVTF 163 >1QZY-A nrPDB Length = 478 Score = 29.6 bits (65), Expect = 4.6, Method: Compositional matrix adjust. Identities = 24/84 (28%), Positives = 32/84 (38%), Gaps = 6/84 (7%) Query: 354 KGGVTEISAADKAEEFRR----QQADFVDLSFPTISSTGPNGAIIHYAPVPETNRTLSLD 409 K G+T I +K E+ R + L+FPT S N HY P L D Sbjct: 188 KPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSL--NNCAAHYTPNAGDTTVLQYD 245 Query: 410 EVYLIDSGAQYKDGTTDVTRTMHF 433 ++ ID G D T+ F Sbjct: 246 DICKIDFGTHISGRIIDCAFTVTF 269 >5THX-A nrPDB Length = 266 Score = 29.6 bits (65), Expect = 4.6, Method: Compositional matrix adjust. Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 10/84 (11%) Query: 483 YLHGTGHGVGSFLNVHEGPCGISYKTFSDEPLEAGMIVTDEPGYY--------EDGAFGI 534 YL TG G+ FL++ + P Y+ F L G+ + YY E G Sbjct: 119 YLLSTGTGIAPFLSITKDPE--IYEQFEKIILVHGVRYKKDLAYYDRFTKELPEHEYLGD 176 Query: 535 RIENVVLVVPVKTKYNFNNRGSLT 558 ++ ++ P+ ++ F +RG LT Sbjct: 177 LVKEKLIYYPIVSREEFEHRGRLT 200 >5CE6-A nrPDB Length = 480 Score = 29.3 bits (64), Expect = 4.9, Method: Compositional matrix adjust. Identities = 38/171 (22%), Positives = 67/171 (39%), Gaps = 6/171 (3%) Query: 358 TEISAADKAEEFRRQQADFVDLSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLI--D 415 TE D A+ + +AD VD+ +P I +G G + L D +I Sbjct: 244 TEKVILDPAKVNCKLKADNVDICYPPIFQSG--GKFDLRPSAVSNDEALYYDSASVIICA 301 Query: 416 SGAQYKDGTTDVTRTMHFGTPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSA 475 GA+YK +++ RT K + +LK AV ++ P G K A S Sbjct: 302 VGARYKSYCSNIARTFLIDADPIQSK-AYEVLLKAQEAVIGSLKP-GNKLSAAYLAAVSV 359 Query: 476 LWDSGLDYLHGTGHGVGSFLNVHEGPCGISYKTFSDEPLEAGMIVTDEPGY 526 + D + G+ + + G++ +D+ ++ GM+ G+ Sbjct: 360 VEKDAPDMVSCLTKSAGTGIGIEFRESGLNINAKNDQIVKEGMVFNVSLGF 410 >5HGQ-A nrPDB Length = 524 Score = 29.3 bits (64), Expect = 5.4, Method: Compositional matrix adjust. Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 13/90 (14%) Query: 184 DLRLKMA-ERNVMWFVVTALD---EIAWLFNLRGSDVEHNPVFFSYAIIGLETIMLFIDG 239 DL L++A E + VV +D EI +F G D HNP F S E M + D Sbjct: 227 DLYLRVAPELYLKMLVVGGIDRVYEIGRVFRNEGIDQTHNPEFTS-----CEFYMAYADY 281 Query: 240 DRIDAPSVKEHLLLDL--GLEAEYRIQVHP 267 + D + E +L + + Y+IQ HP Sbjct: 282 E--DLMKITEDMLARMVYYMHGTYKIQYHP 309 >5EJK-A nrPDB Length = 270 Score = 28.9 bits (63), Expect = 7.3, Method: Compositional matrix adjust. Identities = 27/70 (38%), Positives = 32/70 (45%), Gaps = 7/70 (10%) Query: 100 TPTQEDWLVSVLPEGSRVGVDPLIIPTDYWKKMAKVLRSAGHHLIPVKENLVDK-IWTDR 158 TP Q+ W +VL EG V + I T W+K VL G VK DK IW Sbjct: 207 TPIQKHWRPTVLTEGPPVKIR---IETGEWEKGWNVL-VWGRGYAAVKNRDTDKVIWV-- 260 Query: 159 PERPCKPLLT 168 P R KP +T Sbjct: 261 PSRKVKPDIT 270 >4FW1-A nrPDB Length = 222 Score = 28.9 bits (63), Expect = 7.7, Method: Compositional matrix adjust. Identities = 27/70 (38%), Positives = 32/70 (45%), Gaps = 7/70 (10%) Query: 100 TPTQEDWLVSVLPEGSRVGVDPLIIPTDYWKKMAKVLRSAGHHLIPVKENLVDK-IWTDR 158 TP Q+ W +VL EG V + I T W+K VL G VK DK IW Sbjct: 159 TPIQKHWRPTVLTEGPPVKIR---IETGEWEKGWNVL-VWGRGYAAVKNRDTDKVIWV-- 212 Query: 159 PERPCKPLLT 168 P R KP +T Sbjct: 213 PSRKVKPDIT 222 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3CTZ-A nrPDB 990 0.0 4S2R-P nrPDB 755 0.0 5JR6-A nrPDB 672 0.0 4RGZ-A nrPDB 280 1e-75 2ZSG-A nrPDB 238 7e-63 3Q6D-A nrPDB 233 2e-61 1WY2-A nrPDB 225 5e-59 4ZNG-C nrPDB 222 3e-58 1PV9-A nrPDB 220 1e-57 5CNX-A nrPDB 214 1e-55 5X49-A nrPDB 212 4e-55 2BWY-A nrPDB 201 1e-51 5WZE-A nrPDB 195 5e-50 4PV4-A nrPDB 193 3e-49 5MC5-A nrPDB 187 1e-47 3IG4-A nrPDB 170 2e-42 6A9U-A nrPDB 164 9e-41 4ZWP-A nrPDB 149 3e-36 3L7G-A nrPDB 148 5e-36 Sequences not found previously or not previously below threshold: 4QR8-A nrPDB 111 9e-25 3RVA-A nrPDB 105 6e-23 1O0X-A nrPDB 84 2e-16 3ROR-A nrPDB 82 1e-15 4FO7-A nrPDB 79 8e-15 4B28-A nrPDB 74 2e-13 4A6V-A nrPDB 73 4e-13 1QXW-A nrPDB 72 9e-13 3TAV-A nrPDB 71 1e-12 3MR1-A nrPDB 70 2e-12 6MRF-A nrPDB 69 4e-12 1CHM-A nrPDB 67 2e-11 3TB5-A nrPDB 66 4e-11 4IU6-A nrPDB 66 5e-11 2B3K-A nrPDB 66 5e-11 4FUK-A nrPDB 66 5e-11 1XGN-A nrPDB 63 4e-10 3S6B-A nrPDB 62 9e-10 4KM3-A nrPDB 61 2e-09 3CB5-A nrPDB 58 9e-09 5CE6-A nrPDB 56 7e-08 5LYW-A nrPDB 49 7e-06 1QZY-A nrPDB 49 7e-06 3BIQ-A nrPDB 47 3e-05 5E5B-A nrPDB 46 5e-05 6A8M-A nrPDB 44 2e-04 2V6C-A nrPDB 40 0.002 2Q8K-A nrPDB 39 0.008 6F0K-D nrPDB 32 0.89 2FGT-A nrPDB 31 1.3 1V0D-A nrPDB 31 1.5 1H78-A nrPDB 30 2.6 4ADY-A nrPDB 30 3.1 3CLH-A nrPDB 30 3.4 5YK0-A nrPDB 30 3.7 5APN-x nrPDB 29 5.0 >3CTZ-A nrPDB Length = 623 Score = 990 bits (2560), Expect = 0.0, Method: Composition-based stats. Identities = 620/623 (99%), Positives = 620/623 (99%) Query: 1 MPPKVTSELLRQLRQAMRNSEYVTEPIQAYIIPSGDAHQSEYIAPCDCRRAFVSGFDGSA 60 MPPKVTSELLRQLRQAMRNSEYVTEPIQAYIIPSGDAHQSEYIAPCDCRRAFVSGFDGSA Sbjct: 1 MPPKVTSELLRQLRQAMRNSEYVTEPIQAYIIPSGDAHQSEYIAPCDCRRAFVSGFDGSA 60 Query: 61 GTAIITEEHAAMWTDGRYFLQAAKQMDSNWTLMKMGLKDTPTQEDWLVSVLPEGSRVGVD 120 GTAIITEEHAAMWTDGRYFLQAAKQMDSNWTLMKMGLKDTPTQEDWLVSVLPEGSRVGVD Sbjct: 61 GTAIITEEHAAMWTDGRYFLQAAKQMDSNWTLMKMGLKDTPTQEDWLVSVLPEGSRVGVD 120 Query: 121 PLIIPTDYWKKMAKVLRSAGHHLIPVKENLVDKIWTDRPERPCKPLLTLGLDYTGISWKD 180 PLIIPTDYWKKMAKVLRSAGHHLIPVKENLVDKIWTDRPERPCKPLLTLGLDYTGISWKD Sbjct: 121 PLIIPTDYWKKMAKVLRSAGHHLIPVKENLVDKIWTDRPERPCKPLLTLGLDYTGISWKD 180 Query: 181 KVADLRLKMAERNVMWFVVTALDEIAWLFNLRGSDVEHNPVFFSYAIIGLETIMLFIDGD 240 KVADLRLKMAERNVMWFVVTALDEIAWLFNLRGSDVEHNPVFFSYAIIGLETIMLFIDGD Sbjct: 181 KVADLRLKMAERNVMWFVVTALDEIAWLFNLRGSDVEHNPVFFSYAIIGLETIMLFIDGD 240 Query: 241 RIDAPSVKEHLLLDLGLEAEYRIQVHPYKSILSELKALCADLSPREKVWVSDKASYAVSE 300 RIDAPSVKEHLLLDLGLEAEYRIQVHPYKSILSELKALCADLSPREKVWVSDKASYAVSE Sbjct: 241 RIDAPSVKEHLLLDLGLEAEYRIQVHPYKSILSELKALCADLSPREKVWVSDKASYAVSE 300 Query: 301 TIPKDHRCCMPYTPICIAKAVKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGGVTEI 360 TIPKDHRCCMPYTPICIAKAVKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGGVTEI Sbjct: 301 TIPKDHRCCMPYTPICIAKAVKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGGVTEI 360 Query: 361 SAADKAEEFRRQQADFVDLSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQY 420 SAADKAEEFRRQQADFVDLSFPTISSTGP GAIIHYAPVPETNRTLSLDEVYLIDSGAQY Sbjct: 361 SAADKAEEFRRQQADFVDLSFPTISSTGPTGAIIHYAPVPETNRTLSLDEVYLIDSGAQY 420 Query: 421 KDGTTDVTRTMHFGTPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSALWDSG 480 KDGTTDVTRTMHF TPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSALWDSG Sbjct: 421 KDGTTDVTRTMHFETPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSALWDSG 480 Query: 481 LDYLHGTGHGVGSFLNVHEGPCGISYKTFSDEPLEAGMIVTDEPGYYEDGAFGIRIENVV 540 LDYLHGTGHGVGSFLNVHEGPCGISYKTFSDEPLEAGMIVTDEPGYYEDGAFGIRIENVV Sbjct: 481 LDYLHGTGHGVGSFLNVHEGPCGISYKTFSDEPLEAGMIVTDEPGYYEDGAFGIRIENVV 540 Query: 541 LVVPVKTKYNFNNRGSLTFEPLTLVPIQTKMIDVDSLTDKECDWLNNYHLTCRDVIGKEL 600 LVVPVKTKYNFNNRGSLT EPLTLVPIQTKMIDVDSLTDKECDWLNNYHLTCRDVIGKEL Sbjct: 541 LVVPVKTKYNFNNRGSLTLEPLTLVPIQTKMIDVDSLTDKECDWLNNYHLTCRDVIGKEL 600 Query: 601 QKQGRQEALEWLIRETQPISKQH 623 QKQGRQEALEWLIRETQPISKQH Sbjct: 601 QKQGRQEALEWLIRETQPISKQH 623 >4S2R-P nrPDB Length = 639 Score = 755 bits (1948), Expect = 0.0, Method: Composition-based stats. Identities = 262/628 (41%), Positives = 374/628 (59%), Gaps = 32/628 (5%) Query: 8 ELLRQLRQAMRNSEYV-----TEPIQAYIIPSGDAHQSEYIAPCDCRRAFVSGFDGSAGT 62 E L +LR ++ +SE V ++P+ AY++PS DAH SEY+A D R F+SGF GS Sbjct: 28 EKLAKLR-SLFHSERVLALTSSKPMVAYLLPSTDAHHSEYLADYDFRVKFLSGFSGSNAY 86 Query: 63 AIITEEHAAMWTDGRYFLQAAKQMDSN-WTLMKMGLKDTPTQEDWLVSVLPEGSRVGVDP 121 ++T+ A +WTDGRYF QA Q+DSN W LMK G D+ T DWLV L GS +G DP Sbjct: 87 VVVTDREALLWTDGRYFTQAGNQLDSNSWKLMKQGQPDSITVVDWLVRELERGSVIGFDP 146 Query: 122 LIIPTDYWKKMAKVLRSAGHHLIPVKENLVDKIWTDRPERPCKPLLTLGLDYTGISWKDK 181 + D K K L++AG + + NLVD+ WTDRP +P++ L ++ TG++ K Sbjct: 147 TLSTFDAGSKTFKRLKAAGLQPVSIPGNLVDEFWTDRPRLAGEPVVVLDVEDTGLTTSKK 206 Query: 182 VADLRLKMAERNVMWFVVTALDEIAWLFNLRGSDVEHNPVFFSYAIIGLETIMLFIDGDR 241 V +LR K+ ++ V T LD++ WL N+RGSD+ +NP+ +SY + + I +FID ++ Sbjct: 207 VENLREKLKQKKCDAAVFTLLDDVMWLLNIRGSDIPYNPLAYSYLFVAMREIHVFIDNEK 266 Query: 242 IDAPSVKEHLLLDLGLEAEYRIQVHPYKSILS----ELKALCADLSPREKVWVSDKASYA 297 +D S + H + + +HPY + S LKA A P V+++ + +YA Sbjct: 267 LDEKS-RAHF-------HKSNVSIHPYGEVYSWISNWLKAKEASKEP-HMVYLTPETNYA 317 Query: 298 VSETIPKDHRCCMPYTPICIAKAVKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGG- 356 + I +++ + + + AKA KN E +GMR +H++D+ AL E WLEKE+ G Sbjct: 318 IGSIIGEEN-SMVDTSLVQTAKATKNDHEMQGMRNSHLRDSAALVEFLCWLEKELLSGKR 376 Query: 357 VTEISAADKAEEFRRQQADFVDLSFPTISSTGPNGAIIHYAPVPET-NRTLSLDEVYLID 415 TEI ADK + R Q +V LSF TIS+ G + A+ HY P+ E+ NR + ++V+L+D Sbjct: 377 YTEIELADKIDHLRSLQDKYVTLSFDTISAVGDHAALPHYKPLGESGNRKAAANQVFLLD 436 Query: 416 SGAQYKDGTTDVTRTMHFGTPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSA 475 SGA Y DGTTDVTRT+ + P T VLKGHI ++ A FP G G LD+ R A Sbjct: 437 SGAHYGDGTTDVTRTVWYTNPPKEFILHNTLVLKGHINLARAKFPDGIYGSRLDTLTRDA 496 Query: 476 LWDSGLDYLHGTGHGVGSFLNVHEGPCGISYKT-FSDEPLEAGMIVTDEPGYYEDGAFGI 534 LW GLD+ HGTGHGVG +LNVHEGP GI +++ + L A ++T EPG+Y +GI Sbjct: 497 LWKLGLDFEHGTGHGVGHYLNVHEGPIGIGHRSVPTGGELHASQVLTIEPGFYAKEKYGI 556 Query: 535 RIENV---VLVVPVKTKYNFNNRGSLTFEPLTLVPIQTKMIDVDSLTDKECDWLNNYHLT 591 RIEN V V + NF LTF+ LTLVPIQT ++D L ++E +WLN YH Sbjct: 557 RIENCYETVEAVVMSKAQNF-----LTFKSLTLVPIQTSIVDKSLLIEEEINWLNQYHAR 611 Query: 592 CRDVIGKELQKQGRQEALEWLIRETQPI 619 +G+ LQK+G+ + L+WL +PI Sbjct: 612 VLKEVGEHLQKRGKTDELKWLAEACKPI 639 >5JR6-A nrPDB Length = 664 Score = 672 bits (1734), Expect = 0.0, Method: Composition-based stats. Identities = 208/662 (31%), Positives = 334/662 (50%), Gaps = 69/662 (10%) Query: 7 SELLRQLRQAMRNSEYVTEPIQAYIIPSGDAHQSEYIAPCDCRRAFVSGFDGSAGTAIIT 66 + L +LR M+ ++ I YI+ + D H SE I D + ++ + G+ G I+T Sbjct: 14 AARLEELRTIMKKNK-----IDVYILINSDEHNSEIINEKDKKIVKITNYSGADGILIVT 68 Query: 67 EEHAAMWTDGRYFLQAAKQMDSNWTLMKMGLKDTPTQEDWLVSVLPEGSRVGVDPLIIPT 126 ++ ++ + Y LQA ++D N +++ D + +S L E + + D Sbjct: 69 KDKPILYVNALYELQAMNELDQNLFTLRISRIDNRDEIFETISSL-EFNTIAFDGKNTSV 127 Query: 127 DYWKKMAKVLRSAGHHLIPVKENLVDKIWTDRPERPCKPLLTLGL--------------- 171 +++K+ K L +A V++ + + + D ++ + +L + Sbjct: 128 VFYEKLRKALLNAYPKKKIVEKIIYNNNFDDVNKKDDENVLNFLVLEKSLVEIKDYPVNN 187 Query: 172 --------DYTGISWKDKVADLR--LKMAERNVMWFVVTALDEIAWLFNLRGSDVEHNPV 221 Y G +K+ L+ L +NV +++ LDEIA+L NLRG D +++P+ Sbjct: 188 KTLYIHDRKYNGACAGEKIDKLKQSLMYDIKNVDNLLLSELDEIAYLLNLRGYDYQYSPL 247 Query: 222 FFSYAIIGLE-------TIMLFIDGDRIDAPSVKEHLLLDLGLEAEYRIQVHPYKSILSE 274 F+SY + + I+ F + A VK LL++ ++ V Y+ I+ Sbjct: 248 FYSYLLFQFDREEQDFSKIVFFTTVKNLPA-DVKN--LLEIN-----KVIVKEYEEIVPY 299 Query: 275 LKALCADLSPREKVWVSDKASYAVSE---------TIPKDHRCCMPYTPICIAKAVKNSA 325 L+ + P+ D Y +S + + +P+ KAVKN Sbjct: 300 LRDVVIPSIPKHNDDNPDFKKYDISLSPYINLMIYKLFDRKNVLLQNSPVVKMKAVKNDV 359 Query: 326 ESEGMRRAHIKDAVALCELFNWLEKEVPKGGV---TEISAADKAEEFRRQQADFVDLSFP 382 E + M++AHI D +AL + F+W E++ + TE+S K + FR + +F+ SF Sbjct: 360 EIDNMKQAHILDGLALLQFFHWCEQKRKTKELFNETEMSLRHKVDYFRSTKKNFIFPSFS 419 Query: 383 TISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDVTRTMHFGTPTAYEKE 442 TIS++GPN A+IHY +TN T+ +YL+DSG QY GTTDVTRT HFG PTA EK Sbjct: 420 TISASGPNAAVIHYECTDKTNATIK-PAIYLLDSGGQYLHGTTDVTRTTHFGEPTAEEKR 478 Query: 443 CFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSALWDSGLDYLHGTGHGVGSFLNVHEGPC 502 +T VLKGH+ + +F + T LD AR L+++ +DY HGTGHGVG LNVHEG C Sbjct: 479 IYTLVLKGHLRLRKVIFASYTNSSALDFIARENLFNNFMDYNHGTGHGVGLTLNVHEGGC 538 Query: 503 GISYKTFSDEPLEAGMIVTDEPGYYEDGAFGIRIENVVLVVPVKTKYNFNNRGSLTFEPL 562 I PL+ M++++EPGYY FG+RIEN+ V+ +K + L+F+ L Sbjct: 539 SIG--PVGGAPLKKNMVLSNEPGYYMKDKFGVRIENMQYVI---SKEITDTTEYLSFDDL 593 Query: 563 TLVPIQTKMIDVDSLTDKECDWLNNYHLTCRDVIGKELQKQGRQEALE----WLIRETQP 618 T+ P + K++D LT++E LN YH T R+ + L KQ QE E +LI T+P Sbjct: 594 TMYPYEKKLLDFSLLTNQEIKELNEYHTTIRNTL-LPLVKQSPQEYGESVEKYLIEITEP 652 Query: 619 IS 620 I+ Sbjct: 653 IA 654 >4RGZ-A nrPDB Length = 367 Score = 280 bits (717), Expect = 1e-75, Method: Composition-based stats. Identities = 84/298 (28%), Positives = 140/298 (46%), Gaps = 24/298 (8%) Query: 266 HPYKSILSELKALCADLSPREKVWVSDKASYAVSETIPK--DHRCCMPYTP-ICIAKAVK 322 +PYK +++K + EK+ + D V D P +P I + +K Sbjct: 85 NPYKIFATKIKETFKE---GEKLLIDDTMPVGVFLKAKDIFDKYSLHPISPVISELREIK 141 Query: 323 NSAESEGMRRA-HIKDAVALCELFNWLEKEVPKGGVTEISAADKAEEFRRQQADFVDLSF 381 + E + ++A I D V + ++E ++ G +E A++ E + + D+SF Sbjct: 142 DKDEIKAHKKAAEIVDKV----FYRFIEGKLE--GKSERELANRIEYMIKNEFGADDVSF 195 Query: 382 PTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDVTRTMHFGTPTAYEK 441 I ++GPNGA H+ P ++R + +V + D GA+Y +DVTRT+ G P+ K Sbjct: 196 EPIVASGPNGANPHHRP---SHRKIRKGDVVIFDYGAKYLGYCSDVTRTVVVGPPSEEVK 252 Query: 442 ECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSALWDSGLD--YLHGTGHGVGSFLNVHE 499 + + V + V G ++D+ AR + G ++H TGHG+G ++VHE Sbjct: 253 KVYEIVKEAQETAVQKVA-EGIPAEVVDATARGIISKYGYGEYFIHRTGHGLG--IDVHE 309 Query: 500 GPCGISYKTFSDEPLEAGMIVTDEPGYYEDGAFGIRIENVVLVVPVKTKYNFNNRGSL 557 P + + L+ GM+ T EPG Y G FG+RIE+ V +V K N L Sbjct: 310 EPY---ISPGNKKILKDGMVFTIEPGIYLQGKFGVRIEDDVALVDKKGIRLTNADREL 364 >2ZSG-A nrPDB Length = 359 Score = 238 bits (606), Expect = 7e-63, Method: Composition-based stats. Identities = 90/369 (24%), Positives = 157/369 (42%), Gaps = 35/369 (9%) Query: 180 DKVADLRLKMAERNVMWFVVTALDEIAWLFNLRGSDVEHNPVFFSYAIIGLETIMLFIDG 239 D+ L ++E + F++ ++ A R S V + S+ +I+L + Sbjct: 2 DRSERLIQLISEEGIDAFLIMNIENSA-----RASSVYFSGFTGSF------SIILISEN 50 Query: 240 DRIDAPSVKEHLLLDLGLEAEYRIQVHPYKSILSELKALCADLSPREKVWVSDKASYA-- 297 R+ + + E ++ ++ + LK DL + ++ S + Sbjct: 51 TRLLITDSR--YTVQAKQETDFEVREVKGGDFIDVLKKTVNDLKIKTIALEEERVSLSLF 108 Query: 298 --VSETIPKDHRCCMPYTPICIAKAVKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKG 355 +S + + + VK+ E E IK A+ + E + + Sbjct: 109 RRISSAFGDRKFIGIDDE-VKQMRMVKDEGEIE-----KIKQAIEISERAFLETVQQIRA 162 Query: 356 GVTEISAADKAEEFRRQQADFVDLSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLID 415 G+TE A E R++ ++F TI ++G A+ H +++ + +V +ID Sbjct: 163 GMTEKEIAALLEYTMRKEGA-EGVAFDTIVASGCRSALPHGKA---SDKVVERGDVIVID 218 Query: 416 SGAQYKDGTTDVTRTMHFGTPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSA 475 GA Y++ D+TR + G P+ KE + VL+ + G G LLDS AR Sbjct: 219 FGATYENYCADITRVVSIGEPSDEVKEVHSIVLEAQERAL-KIAKAGVTGKLLDSVAREF 277 Query: 476 LWDSGLD--YLHGTGHGVGSFLNVHEGPCGISYKTFSDEPLEAGMIVTDEPGYYEDGAFG 533 + + G + H GHG+G L VHEGP + +D PL ++ T EPG Y +G FG Sbjct: 278 IREKGYGEFFGHSLGHGIG--LEVHEGP---AISFRNDSPLPENVVFTVEPGIYLEGKFG 332 Query: 534 IRIENVVLV 542 IRIE V++ Sbjct: 333 IRIEEDVVL 341 Score = 38.2 bits (87), Expect = 0.012, Method: Composition-based stats. Identities = 23/112 (20%), Positives = 46/112 (41%), Gaps = 10/112 (8%) Query: 25 EPIQAYIIPSGDAHQSEYIAPCDCRRAFVSGFDGSAGTAIITEEHAAMWTDGRYFLQAAK 84 E I A++I + + + SGF GS +I+E + TD RY +QA + Sbjct: 14 EGIDAFLIMNIE-------NSARASSVYFSGFTGSFSIILISENTRLLITDSRYTVQAKQ 66 Query: 85 QMDSNWTLMKMGLKDTPTQEDWLVSVLPEGSRVGVDPLIIPTDYWKKMAKVL 136 + D +K G D V+ L + + ++ + +++++ Sbjct: 67 ETDFEVREVKGG--DFIDVLKKTVNDL-KIKTIALEEERVSLSLFRRISSAF 115 >3Q6D-A nrPDB Length = 356 Score = 233 bits (595), Expect = 2e-61, Method: Composition-based stats. Identities = 87/382 (22%), Positives = 161/382 (42%), Gaps = 37/382 (9%) Query: 180 DKVADLRLKMAERNVMWFVVTALDEIAWLFNLRGSDVEHNPVFFSYAIIGLETIMLFIDG 239 +K+ LR E + ++T ++ N G+ +I + D Sbjct: 5 EKIERLRSAFDEAGIDGILLTNEHSRRYMANFTGTA--------GVVLISKKRAQFITDF 56 Query: 240 DRIDAPSVKEHLLLDLGLEAEYRIQVHPYKSILSELKALCADLSPREKVWVSDKASYAVS 299 ++ S + +G E V I+ E+ +L ++ + D +Y+ Sbjct: 57 RYVEQASKQA-----VGYE-----IVQHAGLIIDEVAKQVKELGIQKLGFEQDTLTYSSY 106 Query: 300 ETIPKD-HRCCMPYT-PICIAKAVKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGGV 357 + +P + + + +K +E + ++ A A + +++ + GV Sbjct: 107 SAHKEAIDAEFIPTSGLVEKLRLIKTDSEIKILKEAAQIADAAFEHILSFI-----RPGV 161 Query: 358 TEISAADKAEEFRRQQADFVDLSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSG 417 +EI +++ E F R+Q SF I ++G A+ H + + + + +D G Sbjct: 162 SEIEVSNELEFFMRKQGA-TSSSFDIIVASGLRSALPHGVA---SEKVIETGDFVTLDFG 217 Query: 418 AQYKDGTTDVTRTMHFGTPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSALW 477 A YK +D+TRT+ G P+ KE + VL+ + + G G D+ R + Sbjct: 218 AYYKGYCSDITRTIAVGEPSDKLKEIYNIVLEAQLRGVNGIK-AGLTGREADALTRDYIT 276 Query: 478 DSGLD--YLHGTGHGVGSFLNVHEGPCGISYKTFSDEPLEAGMIVTDEPGYYEDGAFGIR 535 + G + H TGHG+G L +HE P G++++ SD LE GM VT EPG Y G G+R Sbjct: 277 EKGYGEYFGHSTGHGIG--LEIHEAP-GLAFR--SDTVLEPGMAVTVEPGIYIPGIGGVR 331 Query: 536 IENVVLVVPVKTKYNFNNRGSL 557 IE+ ++V + + L Sbjct: 332 IEDDIIVTSEGNEVITKSPKEL 353 Score = 35.9 bits (81), Expect = 0.054, Method: Composition-based stats. Identities = 27/131 (20%), Positives = 50/131 (38%), Gaps = 20/131 (15%) Query: 8 ELLRQLRQAMRNSEYVTEPIQAYIIPSGDAHQSEYIAPCDCRRAFVSGFDGSAGTAIITE 67 E + +LR A + I ++ + H Y+A F G+AG +I++ Sbjct: 5 EKIERLRSAFDEA-----GIDGILL--TNEHSRRYMA----------NFTGTAGVVLISK 47 Query: 68 EHAAMWTDGRYFLQAAKQMDSNWTLMKMGLKDTPTQEDWLVSVLPEGSRVGVDPLIIPTD 127 + A TD RY QA+KQ + GL + V L ++G + + Sbjct: 48 KRAQFITDFRYVEQASKQAVGYEIVQHAGLI--IDEVAKQVKELG-IQKLGFEQDTLTYS 104 Query: 128 YWKKMAKVLRS 138 + + + + Sbjct: 105 SYSAHKEAIDA 115 >1WY2-A nrPDB Length = 351 Score = 225 bits (573), Expect = 5e-59, Method: Composition-based stats. Identities = 86/383 (22%), Positives = 153/383 (39%), Gaps = 43/383 (11%) Query: 180 DKVADLRLKMAERNVMWFVVTALDEIAWLFNLRGSDVEHNPVFFSYAIIGLETIMLFIDG 239 +KV + M + ++ ++ + + + G+ +P+ Y +I E+ L++ Sbjct: 6 EKVKKIIEFMDKNSIDAVLIAKNPNVYY---ISGA----SPLAGGYILITGESATLYV-- 56 Query: 240 DRIDAPSVKEHLLLDLGLEAEYRIQVHPYKSILSELKALCADLSPREKVWVSDKASYAVS 299 P ++ + + E I V +K + KAL S + Y Sbjct: 57 -----PELEYEMAKE-----ESNIPVEKFKKMDEFYKALEGIKSLG----IESSLPYGFI 102 Query: 300 ETIPKDHRCC---MPYTPICIAKAVKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGG 356 E + K I + +K+ E + + +A + + E G Sbjct: 103 EELKKKANIKEFKKVDDVIRDMRIIKSEKEIKIIEKA-----CEIADKAVMAAIEEITEG 157 Query: 357 VTEISAADKAEEFRRQQADFVDLSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDS 416 E A K E + +F TI ++G A+ H +++ + ++ +ID Sbjct: 158 KKEREVAAKVEYLMKMNGA-EKPAFDTIIASGYRSALPHGVA---SDKRIERGDLVVIDL 213 Query: 417 GAQYKDGTTDVTRTMHFGTPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSAL 476 GA Y+ +D+TRT+ G+P +KE + VL+ + P G LDS AR+ + Sbjct: 214 GALYQHYNSDITRTIVVGSPNEKQKEIYEIVLEAQKKAVESAKP-GITAKELDSIARNII 272 Query: 477 WDSGLD--YLHGTGHGVGSFLNVHEGPCGISYKTFSDEPLEAGMIVTDEPGYYEDGAFGI 534 + G + H GHGVG L VHE P + + L GM++T EPG Y G+ Sbjct: 273 AEYGYGEYFNHSLGHGVG--LEVHEWP---RVSQYDETVLREGMVITIEPGIYIPKIGGV 327 Query: 535 RIENVVLVVPVKTKYNFNNRGSL 557 RIE+ +L+ +K L Sbjct: 328 RIEDTILITKNGSKRLTKTEREL 350 >4ZNG-C nrPDB Length = 362 Score = 222 bits (566), Expect = 3e-58, Method: Composition-based stats. Identities = 84/366 (22%), Positives = 151/366 (41%), Gaps = 26/366 (7%) Query: 181 KVADLRLKMAERNVMWFVVTALDEIAWLFNLRGSDVEHNPVFFSYAIIGLETIMLFIDGD 240 K+ + + ++ V +T + +L L + H + I T MLF Sbjct: 3 KIERISAFLNDKEVDMTFITNPTTLNYLTGL--AIDPHERIA-GLMIFRDSTPMLFTPA- 58 Query: 241 RIDAPSVKEHLL-LDLGLEAEYRIQVHPYKSILSELKALCADLSPREKVWVSDKASYAVS 299 ++ KEH LD+ + + +P++ + + +K+ ++ E + + + Sbjct: 59 -LEVEKAKEHTSGLDIFGYEDSQ---NPWEVVKNHVKSDVKSIAV-EFSDIPLAKTEGLK 113 Query: 300 ETIPKDHRCCMPYTPICIAKAVKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGGVTE 359 + + I + +K++ E E M+ A D C + + GVTE Sbjct: 114 AQFGDINFVNL-TPLIERMRLIKSADEIEKMKVAG--DFADKCFEIGFATAA-ERNGVTE 169 Query: 360 ISAADKAEEFRRQQADFVDLSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQ 419 K E ++ +SF T+ +G A H AP N + +++ L D G Sbjct: 170 SDIVAKIEY-EMKRMGVPQMSFDTLVLSGARAANPHGAP---ENVEIQENKLLLFDLGVM 225 Query: 420 YKDGTTDVTRTMHFGTPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSALWDS 479 +D TRT+ G P ++ E V + A + P G H +D+ AR + + Sbjct: 226 SGGYASDATRTIAIGQPNDFDAEIHKIVKEAQQAAMDFIKP-GVTAHEVDAVARDLITKA 284 Query: 480 GLD--YLHGTGHGVGSFLNVHEGPCGISYKTFSDEPLEAGMIVTDEPGYYEDGAFGIRIE 537 G + H GHG+G ++VHE P S +D ++ GM ++EPG Y G G+RIE Sbjct: 285 GYGEYFNHRLGHGIG--MDVHEYP---SIVAGNDLVIQEGMCFSNEPGIYIPGKVGVRIE 339 Query: 538 NVVLVV 543 + + V Sbjct: 340 DCLYVT 345 >1PV9-A nrPDB Length = 348 Score = 220 bits (561), Expect = 1e-57, Method: Composition-based stats. Identities = 84/384 (21%), Positives = 148/384 (38%), Gaps = 43/384 (11%) Query: 179 KDKVADLRLKMAERNVMWFVVTALDEIAWLFNLRGSDVEHNPVFFSYAIIGLETIMLFID 238 K+++ L M E ++ + + + +P+ Y I+ + L++ Sbjct: 2 KERLEKLVKFMDENSIDRVFIAKPVNVYYFSGT-------SPLGGGYIIVDGDEATLYV- 53 Query: 239 GDRIDAPSVKEHLLLDLGLEAEYRIQVHPYKSILSELKALCADLSPREKVWVSDKASYAV 298 ++ KE L + ++ + I LK E + + SY++ Sbjct: 54 -PELEYEMAKEESKLPV-------VKFKKFDEIYEILKNT-------ETLGIEGTLSYSM 98 Query: 299 SETIPKDHRCC---MPYTPICIAKAVKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKG 355 E + I + +K E E + +A + + E Sbjct: 99 VENFKEKSNVKEFKKIDDVIKDLRIIKTKEEIEIIEKA-----CEIADKAVMAAIEEITE 153 Query: 356 GVTEISAADKAEEFRRQQADFVDLSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLID 415 G E A K E + +F TI ++G A+ H +++ + ++ +ID Sbjct: 154 GKREREVAAKVEYLMKMNGA-EKPAFDTIIASGHRSALPHGVA---SDKRIERGDLVVID 209 Query: 416 SGAQYKDGTTDVTRTMHFGTPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSA 475 GA Y +D+TRT+ G+P ++E + VL+ A P G LDS AR Sbjct: 210 LGALYNHYNSDITRTIVVGSPNEKQREIYEIVLEAQKRAVEAAKP-GMTAKELDSIAREI 268 Query: 476 LWDSGLD--YLHGTGHGVGSFLNVHEGPCGISYKTFSDEPLEAGMIVTDEPGYYEDGAFG 533 + + G ++H GHGVG L +HE P + + L+ GM++T EPG Y G Sbjct: 269 IKEYGYGDYFIHSLGHGVG--LEIHEWP---RISQYDETVLKEGMVITIEPGIYIPKLGG 323 Query: 534 IRIENVVLVVPVKTKYNFNNRGSL 557 +RIE+ VL+ K L Sbjct: 324 VRIEDTVLITENGAKRLTKTEREL 347 >5CNX-A nrPDB Length = 361 Score = 214 bits (545), Expect = 1e-55, Method: Composition-based stats. Identities = 72/237 (30%), Positives = 113/237 (47%), Gaps = 26/237 (10%) Query: 317 IAKAVKNSAESEGMRRA-HIKD-AVALCELFNWLEKEVPKGGVTEISAADKAEEFRRQQA 374 + + +K E E +R A I D F + G++E A + E F RQQ Sbjct: 123 VLRQIKTPEEVEKIRLACGIADRGAEHIRRF-------IQAGMSEREIAAELEWFMRQQG 175 Query: 375 DFVDLSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDVTRTM-HF 433 SF TI ++G GA+ H +++ ++ E +D GA Y+ +D+TRT+ Sbjct: 176 A-EKASFDTIVASGWRGALPHGKA---SDKIVAAGEFVTLDFGALYQGYCSDMTRTLLVN 231 Query: 434 GTPTAYEK----ECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSALWDSGLD--YLHGT 487 G + E + VL+ +A +A+ P G + +D AR + ++G + H T Sbjct: 232 GEGVSAESHLLFNVYQIVLQAQLAAISAIRP-GVRCQQVDDAARRVITEAGYGDYFGHNT 290 Query: 488 GHGVGSFLNVHEGPCGISYKTFSDEPLEAGMIVTDEPGYYEDGAFGIRIENVVLVVP 544 GH +G + VHE P + L+ GM++T EPG Y G G+RIE+VVLV P Sbjct: 291 GHAIG--IEVHEDP---RFSPRDTTTLQPGMLLTVEPGIYLPGQGGVRIEDVVLVTP 342 >5X49-A nrPDB Length = 456 Score = 212 bits (539), Expect = 4e-55, Method: Composition-based stats. Identities = 67/314 (21%), Positives = 116/314 (36%), Gaps = 50/314 (15%) Query: 264 QVHPYKSILSELKALCAD-----LSPREKVWVSDKASYAVSETIPKDHRCCMPYTPICIA 318 + ++ +L ++KA + P SD ++ I Sbjct: 133 TLEEFQHLLPKMKAETNMVWYDWMRPSHAQLHSDYMQPLTEAKAKSKNKVRGVQQLIQRL 192 Query: 319 KAVKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGGVTEISAADKAEEFRRQQADFVD 378 + +K+ AE E M+ A + A E K V E K E R + Sbjct: 193 RLIKSPAEIERMQIAGKLTSQAFIETMF-----TSKAPVEEAFLYAKFEFECRARGA-DI 246 Query: 379 LSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDVTRTMHF-GTPT 437 L++P + + G +HY + N+ + E+ L+D G + +D+TRT G T Sbjct: 247 LAYPPVVAGGNRSNTLHYV---KNNQLIKDGEMVLLDGGCESSCYVSDITRTWPVNGRFT 303 Query: 438 AYEKECFTYVLKGHIAVSAAVFPTGTKGH-----------------LLDSFARSALWDSG 480 A + E + VL+ A FP + + ++ + + + + Sbjct: 304 APQAELYEAVLEIQRDCLALCFPGTSLENIYSMMLTLIGQKLKDLGIMKNIKENNAFKAA 363 Query: 481 LDY-LHGTGHGVGSFLNVHEGPCGISYKTFSDEPLEAGMIVTDEPGYYEDG--------- 530 Y H GH +G ++VH+ P PL+ GM++T EPG Y Sbjct: 364 RKYCPHHVGHYLG--MDVHDTP-----DMPRSLPLQPGMVITIEPGIYIPEDDKDAPEKF 416 Query: 531 -AFGIRIENVVLVV 543 G+RIE+ V+V Sbjct: 417 RGLGVRIEDDVVVT 430 >2BWY-A nrPDB Length = 440 Score = 201 bits (510), Expect = 1e-51, Method: Composition-based stats. Identities = 62/267 (23%), Positives = 104/267 (38%), Gaps = 46/267 (17%) Query: 308 CCMPYTPIC-IAKAVKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGGVTEISAADKA 366 + + P+ + K+ E +RRA A+A + G+ E + Sbjct: 161 TMIDWRPVVHEMRLFKSPEEIAVLRRAGEITAMAHTRAMEKC-----RPGMFEYHLEGEI 215 Query: 367 E-EFRRQQADFVDLSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTT 425 EF R A + S+ TI +G NG I+HY E + ++ LID+G +YK Sbjct: 216 HHEFNRHGARYP--SYNTIVGSGENGCILHYT---ENECEMRDGDLVLIDAGCEYKGYAG 270 Query: 426 DVTRTMHF-GTPTAYEKECFTYVLKGHIAVSAAVFPTGTKGH--------LLDSFARSAL 476 D+TRT G T ++E + VL+ P + ++ + + Sbjct: 271 DITRTFPVNGKFTQAQREIYDIVLESLETSLRLYRPGTSILEVTGEVVRIMVSGLVKLGI 330 Query: 477 WDSGLD-----------YLHGTGHGVGSFLNVHEGPCGISYKTFSDEPLEAGMIVTDEPG 525 +D ++HG H +G L+VH+ Y LE GM++T PG Sbjct: 331 LKGDVDELIAQNAHRPFFMHGLSHWLG--LDVHDVGV---YGQDRSRILEPGMVLTVAPG 385 Query: 526 YY---------EDGAFGIRIENVVLVV 543 Y + GIRIE+ +++ Sbjct: 386 LYIAPDAEVPEQYRGIGIRIEDDIVIT 412 >5WZE-A nrPDB Length = 452 Score = 195 bits (495), Expect = 5e-50, Method: Composition-based stats. Identities = 65/264 (24%), Positives = 109/264 (41%), Gaps = 56/264 (21%) Query: 312 YTPICIAKAVKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGGVTEISAADKAE-EFR 370 Y K ++ +AE RAHI+ A+ +C + G+ E + E EFR Sbjct: 175 YKSANEVKVMRYAAEVSA--RAHIR-AMEVC-----------RPGLFEYHLEAELEYEFR 220 Query: 371 RQQADFVDLSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDVTRT 430 + A ++ +I + G N I+HY E + + ++ LID+G + +D+TRT Sbjct: 221 KGGAKMP--AYGSIVAAGRNACILHYR---ENDAAIKDGDLILIDAGCEIDCYASDITRT 275 Query: 431 MH-FGTPTAYEKECFTYVLKGHIAVSAAVFPT--------GTKGHLLDSFARSALWDSGL 481 G + +K + VL+ ++A + P T + R L + + Sbjct: 276 FPANGRFSPEQKAIYELVLEANMAAFDYIAPGRHWNEAHEATVRVITAGLVRLGLLEGDV 335 Query: 482 D-----------YLHGTGHGVGSFLNVHEGPCGISYKTFSD-EPLEAGMIVTDEPGYYE- 528 D Y+H GH +G ++VH+ Y+ + LE GM +T EPG Y Sbjct: 336 DELIAHEAYKAFYMHRAGHWLG--MDVHDVG---EYRVGGEWRVLEPGMAMTVEPGIYIA 390 Query: 529 ---------DGAFGIRIENVVLVV 543 G+RIE+ V+V Sbjct: 391 PDNTTVAKKWRGIGVRIEDDVVVT 414 >4PV4-A nrPDB Length = 445 Score = 193 bits (489), Expect = 3e-49, Method: Composition-based stats. Identities = 64/259 (24%), Positives = 104/259 (40%), Gaps = 48/259 (18%) Query: 317 IAKAVKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGGVTEISAADKA-EEFRRQQAD 375 + K++ E +RRA A+A + G+ E + EF R A Sbjct: 169 EMRLFKSAEEIAVLRRAGEISALAHTRAMEKC-----RPGMFEYQLEGEILHEFTRHGAR 223 Query: 376 FVDLSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDVTRTMHF-G 434 + ++ TI G NG I+HY E L ++ LID+G +Y+ D+TRT G Sbjct: 224 YP--AYNTIVGGGENGCILHYT---ENECELRDGDLVLIDAGCEYRGYAGDITRTFPVNG 278 Query: 435 TPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHLLDS---------FARSALWDSGLD--- 482 T ++ + VL I S +F GT + + ++ Sbjct: 279 KFTPAQRAVYDIVLAA-INKSLTLFRPGTSIREVTEEVVRIMVVGLVELGILKGDIEQLI 337 Query: 483 --------YLHGTGHGVGSFLNVHE-GPCGISYKTFSDEPLEAGMIVTDEPGYY------ 527 ++HG H +G ++VH+ G G S + LE GM++T EPG Y Sbjct: 338 AEQAHRPFFMHGLSHWLG--MDVHDVGDYGSSDR---GRILEPGMVLTVEPGLYIAPDAD 392 Query: 528 ---EDGAFGIRIENVVLVV 543 + GIRIE+ +++ Sbjct: 393 VPPQYRGIGIRIEDDIVIT 411 >5MC5-A nrPDB Length = 478 Score = 187 bits (474), Expect = 1e-47, Method: Composition-based stats. Identities = 68/307 (22%), Positives = 112/307 (36%), Gaps = 68/307 (22%) Query: 293 KASYAVSETIPKDHRCCMPYTPICIAKAVKNSAESEGMRRAHIKDAVALCELFNWLEKEV 352 +AS+ ++ P I + K E E +R + + A E+ + Sbjct: 155 EASFDGISKFEVNNTILHPE--IVECRVFKTDMELEVLRYTNKISSEAHREVM-----KA 207 Query: 353 PKGGVTEISAADKAEEFRRQQADFVDLSFPTISSTGPNGAIIHYAPVPE-TNRTLSLDEV 411 K G+ E E + + S+ I +G N A++HY +RT+ ++ Sbjct: 208 VKVGMKEYELESLFEHYCYSRGGMRHSSYTCICGSGENSAVLHYGHAGAPNDRTIQNGDM 267 Query: 412 YLIDSGAQYKDGTTDVTRTMH-FGTPTAYEKECFTYVLKGHIAVSAAVFPT--------- 461 L D G +Y +D+T + G TA +K + VL+ AV A+ P Sbjct: 268 CLFDMGGEYYCFASDITCSFPANGKFTADQKAVYEAVLRSSRAVMGAMKPGVWWPDMHRL 327 Query: 462 GTKGHLLDSFARSALWDSGLDYL-----------HGTGHGVGSFLNVHEGPCGISYKTFS 510 + H L+ A + +D + HG GH +G ++VH+ Sbjct: 328 ADRIH-LEELAHMGILSGSVDAMVQAHLGAVFMPHGLGHFLG--IDVHDVGGYPEGVERI 384 Query: 511 DEP----------LEAGMIVTDEPGYY--------------------------EDGAFGI 534 DEP L+ GM++T EPG Y G G+ Sbjct: 385 DEPGLRSLRTARHLQPGMVLTVEPGIYFIDHLLDEALADPARASFLNREVLQRFRGFGGV 444 Query: 535 RIENVVL 541 RIE+VV+ Sbjct: 445 RIEDVVV 451 >3IG4-A nrPDB Length = 427 Score = 170 bits (430), Expect = 2e-42, Method: Composition-based stats. Identities = 61/247 (24%), Positives = 105/247 (42%), Gaps = 33/247 (13%) Query: 312 YTPICIAKAVKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGGVTEISAADKAEEFRR 371 Y IC + K E E ++ A + + + K + E + + F Sbjct: 162 YPNICELRVFKTDEEIEIIKEAIAVTKDGIYNVL-----KHAKADMMEYELEAQFD-FTL 215 Query: 372 QQADFVDLSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDVTRTM 431 + + +F TI ++G N ++HY + + + ++ L+D GAQ D++ T Sbjct: 216 KSSGIKHHAFNTILASGKNATVLHY---EDNDAQIQNGDLVLLDLGAQKDYYNADISYTF 272 Query: 432 H-FGTPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSALWDS----------- 479 GT ++ +K+ + VL + + P G K L+ A+ L + Sbjct: 273 PANGTFSSRQKQIYNIVLNALKETTEIIKP-GLKFAALNEHAKKVLAEGCKAVGLIQEDE 331 Query: 480 --GLDYLHGTGHGVGSFLNVHEGPCGISYKTFSDEPLEAGMIVTDEPGYY-EDGAFGIRI 536 Y HG H +G L+ H+ T+ D LE GM++T EPG Y E+ + GIRI Sbjct: 332 ELSKYYYHGVSHFLG--LDTHD------VGTYKDRVLEEGMVITIEPGLYIEEESIGIRI 383 Query: 537 ENVVLVV 543 E+ +LV Sbjct: 384 EDDILVT 390 >6A9U-A nrPDB Length = 455 Score = 164 bits (415), Expect = 9e-41, Method: Composition-based stats. Identities = 56/265 (21%), Positives = 98/265 (36%), Gaps = 48/265 (18%) Query: 306 HRCCMPYTP-ICIAKAVKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGGVTEISAAD 364 ++ P + I + +K+ E MRRA + + F + + T D Sbjct: 172 NKTIKPISKRIAEFRKIKSPQELRIMRRAGQISGRSFNQAF----AKRFRNERT----LD 223 Query: 365 KAEEFRRQQADFVDLSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGT 424 ++ ++ + +TG N IHY + + DE+ L+D+ Sbjct: 224 SFLHYKFISGGCDKDAYIPVVATGSNSLCIHYT---RNDDVMFDDEMVLVDAAGSLGGYC 280 Query: 425 TDVTRTMHF-GTPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHLLD-------SFARSAL 476 D++RT G T +++ + VL + + L + + L Sbjct: 281 ADISRTWPNSGKFTDAQRDLYEAVLNVQRDCIKLCK--ASNNYSLHDIHEKSITLMKQEL 338 Query: 477 WDSGLD----------YLHGTGHGVGSFLNVHEGPCGISYKTFSDEPLEAGMIVTDEPGY 526 + G+D Y H GH +G L+VH+ P Y EPL+ G ++T EPG Sbjct: 339 KNLGIDKVSGWNVEKLYPHYIGHNLG--LDVHDVPKVSRY-----EPLKVGQVITIEPGL 391 Query: 527 YED---------GAFGIRIENVVLV 542 Y GIRIE+ + + Sbjct: 392 YIPNEESFPSYFRNVGIRIEDDIAI 416 >4ZWP-A nrPDB Length = 440 Score = 149 bits (376), Expect = 3e-36, Method: Composition-based stats. Identities = 86/426 (20%), Positives = 139/426 (32%), Gaps = 89/426 (20%) Query: 186 RLKMAERNVMWFVVTALDEIAWLFNLRGSDVEHNPVFFSYAIIGLETIMLFIDGDRIDAP 245 R + N+ V + + + NP F ++ + ++ +I + D P Sbjct: 20 REIIERENLDGVVFHSGQAKRQFLDDMYYPFKVNPQFKAWLPV-IDNPHCWIVANGTDKP 78 Query: 246 SVKEHLLLDLGLEAEYRIQVHPYKSILSELKALCADLSPREKVWVSDKASYAV----SET 301 K + + + + Y + +++ L EK+ DKA +A E Sbjct: 79 --KLIFYRPVDFWHKVPDEPNEYWADYFDIELLVKPDQV-EKLLPYDKARFAYIGEYLEV 135 Query: 302 IPKDHRCCMPYTPICIA----KAVKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGGV 357 M P+ +A K E MR A+ + ++ G Sbjct: 136 AQALGFELMNPEPVMNFYHYHRAYKTQYELACMREANKIAVQG-----HKAARDAFFQGK 190 Query: 358 TEISAADKAEEFRRQQADFVDLSFPTISSTGPNGAIIHYAP----VPETNRTLSLDEVYL 413 +E Q D F I + N AI+HY P T+R+ +L Sbjct: 191 SEFEIQQA--YLLATQHSENDTPFGNIVALNENCAILHYTHFDRVAPATHRS------FL 242 Query: 414 IDSGAQYKDGTTDVTRTMHFGTPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHL-LDSFA 472 ID+GA + D+TRT F + E + + IA+ + P G L LD Sbjct: 243 IDAGANFNGYAADITRTYDFTGEGEF-AELVATMKQHQIALCNQLAPGKLYGELHLDCHQ 301 Query: 473 RSALWDSGLD------------------YLHGTGHGVGSFLNVHE-GPCGISYKTFSDEP 513 R A S + + HG GH +G L VH+ G + EP Sbjct: 302 RVAQTLSDFNIVNLSADEIVAKGITSTFFPHGLGHHIG--LQVHDVGGFMADEQGAHQEP 359 Query: 514 ------------LEAGMIVTDEPGYYEDGA-------------------------FGIRI 536 +EA + T EPG Y + GIRI Sbjct: 360 PEGHPFLRCTRKIEANQVFTIEPGLYFIDSLLGDLAATDNNQHINWDKVAELKPFGGIRI 419 Query: 537 ENVVLV 542 E+ ++V Sbjct: 420 EDNIIV 425 >3L7G-A nrPDB Length = 517 Score = 148 bits (374), Expect = 5e-36, Method: Composition-based stats. Identities = 85/426 (19%), Positives = 139/426 (32%), Gaps = 89/426 (20%) Query: 186 RLKMAERNVMWFVVTALDEIAWLFNLRGSDVEHNPVFFSYAIIGLETIMLFIDGDRIDAP 245 R + N+ V + + + NP F ++ + ++ +I + D P Sbjct: 20 REIIERENLDGVVFHSGQAKRQFLDDMYYPFKVNPQFKAWLPV-IDNPHCWIVANGTDKP 78 Query: 246 SVKEHLLLDLGLEAEYRIQVHPYKSILSELKALCADLSPREKVWVSDKASYAV----SET 301 K + + + + Y + +++ L EK+ DKA +A E Sbjct: 79 --KLIFYRPVDFWHKVPDEPNEYWADYFDIELLVKPDQV-EKLLPYDKARFAYIGEYLEV 135 Query: 302 IPKDHRCCMPYTPICIA----KAVKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGGV 357 M P+ +A K E MR A+ + ++ G Sbjct: 136 AQALGFELMNPEPVMNFYHYHRAYKTQYELACMREANKIAVQG-----HKAARDAFFQGK 190 Query: 358 TEISAADKAEEFRRQQADFVDLSFPTISSTGPNGAIIHYAP----VPETNRTLSLDEVYL 413 +E Q D + I + N AI+HY P T+R+ +L Sbjct: 191 SEFEIQQA--YLLATQHSENDNPYGNIVALNENCAILHYTHFDRVAPATHRS------FL 242 Query: 414 IDSGAQYKDGTTDVTRTMHFGTPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHL-LDSFA 472 ID+GA + D+TRT F + E + + IA+ + P G L LD Sbjct: 243 IDAGANFNGYAADITRTYDFTGEGEF-AELVATMKQHQIALMNQLAPGKLYGELHLDCHQ 301 Query: 473 RSALWDSGLD------------------YLHGTGHGVGSFLNVHE-GPCGISYKTFSDEP 513 R A S + + HG GH +G L VH+ G + EP Sbjct: 302 RVAQTLSDFNIVDLSADEIVAKGITSTFFPHGLGHHIG--LQVHDVGGFMADEQGAHQEP 359 Query: 514 ------------LEAGMIVTDEPGYYEDGA-------------------------FGIRI 536 +EA + T EPG Y + GIRI Sbjct: 360 PEGHPFLRCTRKIEANQVFTIEPGLYFIDSLLGDLAATDNNQHINWDKVAELKPFGGIRI 419 Query: 537 ENVVLV 542 E+ ++V Sbjct: 420 EDNIIV 425 >4QR8-A nrPDB Length = 443 Score = 111 bits (277), Expect = 9e-25, Method: Composition-based stats. Identities = 51/282 (18%), Positives = 95/282 (33%), Gaps = 70/282 (24%) Query: 319 KAVKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGGVTEISAADKAEEFRRQQADFVD 378 ++ K E MR A +A+ + +E + G++E D Sbjct: 159 RSFKTEYELACMREA---QKMAVNG--HRAAEEAFRSGMSEFDI--NIAYLTATGHRDTD 211 Query: 379 LSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDVTRTMHFGTPTA 438 + + I + + A++HY + ++ +L+D+GA+Y D+TRT + Sbjct: 212 VPYSNIVALNEHAAVLHYTKLD--HQAPEEMRSFLLDAGAEYNGYAADLTRTWSAKSDND 269 Query: 439 YEKECFTYVLKGHIAVSAAVFPTGTKG-----------------HLLDSFARSALWDSGL 481 Y + V +A+ A + + ++ + A+ ++ L Sbjct: 270 YAQLVKD-VNDEQLALIATMKAGVSYVDYHIQFHQRIAKLLRKHQIITDMSEEAMVENDL 328 Query: 482 D---YLHGTGHGVGSFLNVHE-GPCGISYKTFS------------DEPLEAGMIVTDEPG 525 HG GH +G L VH+ L+ GM++T EPG Sbjct: 329 TGPFMPHGIGHPLG--LQVHDVAGFMQDDSGTHLAAPAKYPYLRCTRILQPGMVLTIEPG 386 Query: 526 YYEDGA-------------------------FGIRIENVVLV 542 Y + GIRIE+ V++ Sbjct: 387 IYFIESLLAPWREGQFSKHFNWQKIEALKPFGGIRIEDNVVI 428 >3RVA-A nrPDB Length = 451 Score = 105 bits (262), Expect = 6e-23, Method: Composition-based stats. Identities = 57/302 (18%), Positives = 98/302 (32%), Gaps = 73/302 (24%) Query: 319 KAVKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGGVTEISAADKAEEFRRQQADFVD 378 +A K E + MR A+ + ++ + G +E RQ + D Sbjct: 157 RAYKTDYELDCMREANKLAVAG-----HKAAEQAFREGKSEFDINLAYAAASRQGDN--D 209 Query: 379 LSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDVTRTMHFGTP-- 436 + + +I + + +I+HY +LID+GA Y D+TRT Sbjct: 210 VPYTSIVALNEHASILHYMQCDT--VAPKESRSFLIDAGANYHGYAADITRTYAQEGVHN 267 Query: 437 TAYEKECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSALWDSGLD-------------- 482 +A ++ V K + + ++ P G + A + D Sbjct: 268 SAMFRDLIQAVDKVTLTLVDSLKP-GVAYTDIHLLAHDGIAQILHDTGMVNLTPPEIVEM 326 Query: 483 ------YLHGTGHGVGSFLNVHEGPCGISYKTFSDEP-------------LEAGMIVTDE 523 + HG GH +G L VH+ ++ + +P +EA + T E Sbjct: 327 GITRTFFPHGIGHFLG--LQVHDVGGLVNDDRGTPKPAPDDHPFLRCTRMVEARQVFTIE 384 Query: 524 PGYYEDGA-------------------------FGIRIENVVLVVPVKTKYNFNNRGSLT 558 PG Y + GIRIE+ + +V N L Sbjct: 385 PGLYFIDSLLRDLKATPASKYINWDTIDAYKPFGGIRIEDNI-IVHRDKNENMTRDLDLN 443 Query: 559 FE 560 E Sbjct: 444 LE 445 >1O0X-A nrPDB Length = 262 Score = 84.0 bits (206), Expect = 2e-16, Method: Composition-based stats. Identities = 46/211 (21%), Positives = 73/211 (34%), Gaps = 18/211 (8%) Query: 321 VKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGGVTEISAADK-AEEFRRQQ-----A 374 +K +E E M++A AVAL E+ ++V G T E F++ + Sbjct: 16 IKTPSEIEKMKKAGKAVAVALREV-----RKVIVPGKTAWDVETLVLEIFKKLRVKPAFK 70 Query: 375 DFVDLSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDVTRTMHFG 434 + + T S ++H P+ E + ++ +D GA Y+ D T G Sbjct: 71 GYGGYKYATCVSVNEE--VVHGLPLKE--KVFKEGDIVSVDVGAVYQGLYGDAAVTYIVG 126 Query: 435 TPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSALWDSGLDYLHGTGHGVGSF 494 KE + + P G + + GHGVG Sbjct: 127 ETDERGKELVRVTREVLEKAIKMIKPGIRLGDVSHCIQETVESVGFNVIRDYVGHGVGRE 186 Query: 495 LNVHEGPCGISYK-TFSDEPLEAGMIVTDEP 524 L HE P +Y + L GM + EP Sbjct: 187 L--HEDPQIPNYGTPGTGVVLRKGMTLAIEP 215 >3ROR-A nrPDB Length = 291 Score = 81.7 bits (200), Expect = 1e-15, Method: Composition-based stats. Identities = 52/237 (21%), Positives = 79/237 (33%), Gaps = 22/237 (9%) Query: 321 VKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGGVTEISAADKAEEFRRQQADFVDL- 379 V+ E MR A A AL E + GVT A E+ + Sbjct: 47 VQTPEVIEKMRVAGRIAAGALAE-----AGKAVAPGVTTDELDRIAHEYLVDNGAYPSTL 101 Query: 380 ---SFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDVTRTMHFGTP 436 FP ST N I H P ++ ++ ID A D T G Sbjct: 102 GYKGFPKSCSTSLNEVICHGIPDST---VITDGDIVNIDVTAYIGGVHGDTNATFPAGDV 158 Query: 437 TAYEKECFTYVLKGHIAVSAAVFPT---GTKGHLLDSFARSALWDSGLDYLHGTGHGVGS 493 + + + V P G +++S+A ++ D+ TGHG+G+ Sbjct: 159 ADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDF---TGHGIGT 215 Query: 494 FLNVHEGPCGISY-KTFSDEPLEAGMIVTDEPGYYEDGAFGIRIENVVLVVPVKTKY 549 H G + Y + + ++ GM T EP GA I + V K + Sbjct: 216 TF--HNGLVVLHYDQPAVETIMQPGMTFTIEPMINL-GALDYEIWDDGWTVVTKDRK 269 >4FO7-A nrPDB Length = 280 Score = 78.6 bits (192), Expect = 8e-15, Method: Composition-based stats. Identities = 41/212 (19%), Positives = 69/212 (32%), Gaps = 16/212 (7%) Query: 321 VKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGGVTEISAADKAEEFRRQQADFVDLS 380 +K + E MR A + A + E+ E K GVT ++ + + Sbjct: 5 IKTPDDIEKMRIAG-RLAAEVLEMI----GEHIKPGVTTEELDRICHDYIVNEQKAIPAP 59 Query: 381 -----FPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDVTRTMHFGT 435 FP T N + H P + L ++ +D D ++ G Sbjct: 60 LNYKGFPKSICTSINHVVCHGIP---NEKPLKEGDILNVDITVIKDGYHGDTSKMFLVGK 116 Query: 436 PTAYEKECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSALWDSGLDYLHGTGHGVGSFL 495 + + + V P G + + + A + GHG+G Sbjct: 117 TPEWADRLCQITQECMYKGISVVRPGAHLGDIGEIIQKHAEKNGFSVVREYCGHGIGKVF 176 Query: 496 NVHEGPCGISY-KTFSDEPLEAGMIVTDEPGY 526 HE P + Y + + L+ GMI T EP Sbjct: 177 --HEEPQVLHYGRAGTGIELKEGMIFTIEPMI 206 >4B28-A nrPDB Length = 470 Score = 74.0 bits (180), Expect = 2e-13, Method: Composition-based stats. Identities = 62/318 (19%), Positives = 108/318 (33%), Gaps = 38/318 (11%) Query: 271 ILSELKALCADLSPREKVWVSDKASYAVSETIPKDHRCCMPYTPICI-AKAVKNSAESEG 329 +E++ L D +P + DK + M + A++VK E Sbjct: 178 FANEVRILLRDHAPGLRRLAVDKVMLHGLRALQAQGFEIMDGEEVTEKARSVKGPDEIRA 237 Query: 330 MRRAHIKDAVALCELFNWLEKEVPKGGVTEISAADKA-EEFRRQQADFVDLSFPTISSTG 388 MR A VA+ ++ ++ +V G E E R+ ++++ + ++G Sbjct: 238 MRCASHACEVAVRKMEDFARSKVGDGVTCENDIWAILHSENVRRGGEWIETR---LLASG 294 Query: 389 PNGAIIHYAPVPETNRTLSLDEVYLIDS---GAQYKDGTTDVTRTMHFGTPTAYEKECFT 445 P P R +E+ D+ GA TD++R+ G + Sbjct: 295 PRSNPWFQECGP---RVCQRNEIISFDTDLVGA--YGICTDISRSWWIGDQKPRADMIYA 349 Query: 446 YVLKG---HIAVSAAVFPTGTKGHLLDSFARSALWDSGLDYLHGTGHGVGSFLNVHEGPC 502 ++ HI + + G L + HGVG E P Sbjct: 350 --MQHGVEHIRTNMEMLKPGVMIPELSANTHVLDAKFQKQKYGCLMHGVGLC---DEWPL 404 Query: 503 GI----SYKTFSDEPLEAGMIVTDEPGYYEDGA-FGIRIENVVLVVPVKTKYNFNNRGSL 557 + D PLE GM + E E+G F I++E+ VL+ Sbjct: 405 VAYPDHAVAGAYDYPLEPGMTLCVEALISEEGGDFSIKLEDQVLITEDG----------- 453 Query: 558 TFEPLTLVPIQTKMIDVD 575 +E LT P ++ V+ Sbjct: 454 -YENLTKYPFDPALMGVE 470 >4A6V-A nrPDB Length = 265 Score = 72.8 bits (177), Expect = 4e-13, Method: Composition-based stats. Identities = 39/205 (19%), Positives = 63/205 (30%), Gaps = 5/205 (2%) Query: 321 VKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGGVTEISAADKAEEFRRQQADFVDLS 380 +K + E MR A A L + +++ V G + I E A Sbjct: 5 IKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGYHG 64 Query: 381 FPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDVTRTMHFGTPTAYE 440 +P N + H P + L ++ ID D ++ G PT Sbjct: 65 YPKSVCISINEVVCHGIPDDA--KLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMG 122 Query: 441 KECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSALWDSGLDYLHGTGHGVGSFLNVHEG 500 + + V P + + + + GHG+G HE Sbjct: 123 ERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGRGF--HEE 180 Query: 501 PCGISYKTFSDE-PLEAGMIVTDEP 524 P + Y + L+ GM T EP Sbjct: 181 PQVLHYDSRETNVVLKPGMTFTIEP 205 >1QXW-A nrPDB Length = 252 Score = 71.7 bits (174), Expect = 9e-13, Method: Composition-based stats. Identities = 44/215 (20%), Positives = 68/215 (31%), Gaps = 23/215 (10%) Query: 320 AVKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGGVTEISAAD----KAEEFRRQQAD 375 VK E + ++ +C + K G+T + EE+ A Sbjct: 2 IVKTEEELQALKEIGY-----ICAKVRNTMQAATKPGITTKELDNIAKELFEEYGAISAP 56 Query: 376 FVDLSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDVTRTMHFGT 435 D +FP + N + H P + R + ++ ID A D + G Sbjct: 57 IHDENFPGQTCISVNEEVAHGIP---SKRVIREGDLVNIDVSALKNGYYADTGISFVVGE 113 Query: 436 PTAYEKE-CFTYVLKGHIAVSAAVFPTGTK---GHLLDSFARSALWDSGLDYLHGTGHGV 491 K+ A V P G + + AR + TGHGV Sbjct: 114 SDDPMKQKVCDVATMAFENAIAKVKPGTKLSNIGKAVHNTARQNDLKVIKNL---TGHGV 170 Query: 492 GSFLNVHEGPCGI--SYKTFSDEPLEAGMIVTDEP 524 G L HE P + + L GM++ EP Sbjct: 171 GLSL--HEAPAHVLNYFDPKDKTLLTEGMVLAIEP 203 >3TAV-A nrPDB Length = 286 Score = 71.3 bits (173), Expect = 1e-12, Method: Composition-based stats. Identities = 44/214 (20%), Positives = 70/214 (32%), Gaps = 20/214 (9%) Query: 322 KNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGGVTEISAADKAEEFRRQQADFVDL-- 379 + E + M A AL + ++ K GV+ + AE R+ Sbjct: 35 RTPGELDAMAAAGSIVGAALVAV-----RDAAKAGVSTLELDQVAESVIREAGAVPSFLG 89 Query: 380 --SFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDVTRTMHFGTPT 437 FP + N ++H P L+ ++ ID GA D T GT Sbjct: 90 YHGFPASICSSVNDQVVHGIPSAT--AVLADGDLVSIDCGAILDGWHGDSAWTFAVGTVI 147 Query: 438 AYEKECFTYVLKGHIAVSAAVFPT---GTKGHLLDSFARSALWDSGLDYL---HGTGHGV 491 ++ A AA+ P H ++ R+A + GHG+ Sbjct: 148 PSDEALSEATRLSMEAGIAAMIPGNRLTDVSHAIELGTRAAEKQFDRAFGIVDGYGGHGI 207 Query: 492 GSFLNVHEGPCGISYKTFSDEPLEA-GMIVTDEP 524 G + H P + PL A G ++ EP Sbjct: 208 GRSM--HLDPFLPNEGAPGKGPLLAVGSVLAIEP 239 >3MR1-A nrPDB Length = 252 Score = 70.1 bits (170), Expect = 2e-12, Method: Composition-based stats. Identities = 47/205 (22%), Positives = 69/205 (33%), Gaps = 21/205 (10%) Query: 330 MRRAHIKDAVALCELFNWLEKEVPKGGVTEISAADKAEEFRRQQADFVDL----SFPTIS 385 MR A A E +++ V K VT S D F FP Sbjct: 17 MRAAGKLAA----ETLDFITDHV-KPNVTTNSLNDLCHNFITSHNAIPAPLNYKGFPKSI 71 Query: 386 STGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDVTRTMHFGTPTAYEKECFT 445 T N + H P ++ L ++ ID D +R + G K Sbjct: 72 CTSINHVVCHGIP---NDKPLKNGDIVNIDVTVILDGWYGDTSRMYYVGDVAIKPKRLIQ 128 Query: 446 YVLKGHIAVSAAVFPT---GTKGHLLDSFARSALWDSGLDYLHGTGHGVGSFLNVHEGPC 502 + V P G G+ + S+A + DY TGHG+G H+ P Sbjct: 129 VTYDAMMKGIEVVRPGAKLGDIGYAIQSYAEKHNYSVVRDY---TGHGIGRVF--HDKPS 183 Query: 503 GISY-KTFSDEPLEAGMIVTDEPGY 526 ++Y + + L+ GM T EP Sbjct: 184 ILNYGRNGTGLTLKEGMFFTVEPMI 208 >6MRF-A nrPDB Length = 270 Score = 69.4 bits (168), Expect = 4e-12, Method: Composition-based stats. Identities = 43/231 (18%), Positives = 67/231 (29%), Gaps = 26/231 (11%) Query: 320 AVKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGGVTEISA-----------ADKAEE 368 +K E E MR A + A + ++ K K GV+ + Sbjct: 9 MIKTPDEIEKMRIAG-RLAAEVLDMI----KPHIKAGVSTLELDTICRNHIENVQHAIPA 63 Query: 369 FRRQQADFVDLSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDVT 428 +F T N + H P N+ L ++ ID D Sbjct: 64 CVGYGGAPGRPAFQHSICTSVNHVVCHGIPSE--NKILKNGDILNIDVTVIKDGYHGDTN 121 Query: 429 RTMHFGTPTAYEK-ECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSALWDSGLDYLHGT 487 G T+ + A V G + + + + Sbjct: 122 MMYIVGGETSILANRLCKVAQEAMYRGMATVRDGSYLGDIGHAIQKYVESERFSVVREYC 181 Query: 488 GHGVGSFLNVHEGPCGISYKTFSDEP-LEAGMIVTDEP----GYYEDGAFG 533 GHG+G+ H+ P + Y LEAGM T EP G ++ G Sbjct: 182 GHGIGTVF--HDEPQVLHYGQAGTGMRLEAGMTFTIEPMVNAGVWQTKLLG 230 >1CHM-A nrPDB Length = 401 Score = 67.1 bits (162), Expect = 2e-11, Method: Composition-based stats. Identities = 67/394 (17%), Positives = 130/394 (32%), Gaps = 28/394 (7%) Query: 173 YTGISWKDKVADLRLKMAERNVMWFVVTALDEIAWLFNLRGSDVEHNPVFFSYAIIGLET 232 ++ + ++ A LR +A N+ + T+ I + SD + YA++ E Sbjct: 18 FSAQEYANRQARLRAHLAAENIDAAIFTSYHNINYY-----SDFLYCSFGRPYALVVTED 72 Query: 233 IMLFIDGDRIDAPSVKEHLLLDLGLEAEYRIQVHPYKSILSELKALCADLSPREKVWVSD 292 ++ I ID + + + + + +I L + + + + Sbjct: 73 DVISISA-NIDGGQPWRRTVGTDNIVYTDWQRDNYFAAIQQALPKARRIGIEHDHLNLQN 131 Query: 293 KASYAVSETIPKDHRCCMPYTPIC-IAKAVKNSAE----SEGMRRAHIKDAVALCELFNW 347 + A P + C + +K++ E G R A I A + L + Sbjct: 132 RDKLA--ARYPDAE--LVDVAAACMRMRMIKSAEEHVMIRHGARIADIGGAAVVEALGDQ 187 Query: 348 LEKEVPKGGVTEISAADKAEEFRRQQADFVDLSFPTISSTGPNGAIIHYAPVPETNRTLS 407 + + T+ A+ F D + T +G N A P T R ++ Sbjct: 188 VPEYEVALHATQAMVRAIADTFE----DVELMDTWTWFQSGINTD---GAHNPVTTRKVN 240 Query: 408 LDEVYLIDSGAQYKDGTTDVTRTMHFGTPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHL 467 ++ ++ T + RT+ + + ++ H A + P + Sbjct: 241 KGDILSLNCFPMIAGYYTALERTLFLDHCSDDHLRLWQVNVEVHEAGLKLIKPGARCSDI 300 Query: 468 LDSFARSALWDSGLDY-LHGTGHGVGSFLNVHEGPCGISYKTFSDEPLEAGMIVTDEPGY 526 L L Y G GH G+ + + G+ + D LE GM+V+ EP Sbjct: 301 ARELNEIFLKHDVLQYRTFGYGHSFGTLSHYYGREAGLELREDIDTVLEPGMVVSMEPMI 360 Query: 527 YEDGA----FGIRIENVVLVVPVKTKYNFNNRGS 556 G R E+ +L+V N Sbjct: 361 MLPEGLPGAGGYR-EHDILIVNENGAENITKFPY 393 >3TB5-A nrPDB Length = 264 Score = 66.3 bits (160), Expect = 4e-11, Method: Composition-based stats. Identities = 40/210 (19%), Positives = 68/210 (32%), Gaps = 17/210 (8%) Query: 321 VKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGGVTEISAADKAEEF--RRQQADFVD 378 +K+ E E M + A L +++ + + E+ D E Q + Sbjct: 4 LKSPREIEMMDESGELLADVHRHLRTFIKPGITSWDI-EVFVRDFIESHGGVAAQIGYEG 62 Query: 379 LSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDVTRTMHFGTPTA 438 + T S H P + L ++ +D K +D + G T Sbjct: 63 YKYATCCSINDEIC--HGFPRK---KVLKDGDLIKVDMCVDLKGAISDSCWSYVVGESTP 117 Query: 439 YEKECFTYVLKGH---IAVSAAVFPTGTKGHLLDSFARSALWDSGLDYLHGTGHGVGSFL 495 K I + G GH + ++ + D+ GHG+G + Sbjct: 118 EIDRLMEVTKKALYLGIEQAQVGNRIGDIGHAIQTYVEGEGYGVVRDF---VGHGIGPTI 174 Query: 496 NVHEGPCGISYK-TFSDEPLEAGMIVTDEP 524 HE P Y L+ GM++T EP Sbjct: 175 --HESPMIPHYGEAGKGLRLKEGMVITIEP 202 >4IU6-A nrPDB Length = 384 Score = 65.9 bits (159), Expect = 5e-11, Method: Composition-based stats. Identities = 40/237 (16%), Positives = 71/237 (29%), Gaps = 13/237 (5%) Query: 298 VSETIPKDHRCCMPYTPICIAKAVKNSAESEGMRRAHIKDAVALCELFNWL---EKEVPK 354 V I + P +A+K +++ + + I+ +C L + + K Sbjct: 99 VPSYIQRPDYADHPLGMSESEQALKGTSQIKLLSSEDIEGMRLVCRLAREVLDVAAGMIK 158 Query: 355 GGVTEISAADKAEEFRRQQADFVDL----SFPTISSTGPNGAIIHYAPVPETNRTLSLDE 410 GVT + + +FP T N I H P R L + Sbjct: 159 PGVTTEEIDHAVHLACIARNCYPSPLNYYNFPKSCCTSVNEVICHGIPDR---RPLQEGD 215 Query: 411 VYLIDSGAQYKDGTTDVTRTMHFGTPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHLLDS 470 + +D D+ T G ++ + + AV P L + Sbjct: 216 IVNVDITLYRNGYHGDLNETFFVGEVDDGARKLVQTTYECLMQAIDAVKPGVRYRELGNI 275 Query: 471 FARSALWDSGLDYLHGTGHGVGSFLNVHEGPCGISYKTFSD-EPLEAGMIVTDEPGY 526 + A + GHG+ H P Y +++G + T EP Sbjct: 276 IQKHAQANGFSVVRSYCGHGIHKLF--HTAPNVPHYAKNKAVGVMKSGHVFTIEPMI 330 >2B3K-A nrPDB Length = 329 Score = 65.9 bits (159), Expect = 5e-11, Method: Composition-based stats. Identities = 40/237 (16%), Positives = 71/237 (29%), Gaps = 13/237 (5%) Query: 298 VSETIPKDHRCCMPYTPICIAKAVKNSAESEGMRRAHIKDAVALCELFNWL---EKEVPK 354 V I + P +A+K +++ + + I+ +C L + + K Sbjct: 44 VPSYIQRPDYADHPLGMSESEQALKGTSQIKLLSSEDIEGMRLVCRLAREVLDVAAGMIK 103 Query: 355 GGVTEISAADKAEEFRRQQADFVDL----SFPTISSTGPNGAIIHYAPVPETNRTLSLDE 410 GVT + + +FP T N I H P R L + Sbjct: 104 PGVTTEEIDHAVHLACIARNCYPSPLNYYNFPKSCCTSVNEVICHGIPDR---RPLQEGD 160 Query: 411 VYLIDSGAQYKDGTTDVTRTMHFGTPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHLLDS 470 + +D D+ T G ++ + + AV P L + Sbjct: 161 IVNVDITLYRNGYHGDLNETFFVGEVDDGARKLVQTTYECLMQAIDAVKPGVRYRELGNI 220 Query: 471 FARSALWDSGLDYLHGTGHGVGSFLNVHEGPCGISYKTFSD-EPLEAGMIVTDEPGY 526 + A + GHG+ H P Y +++G + T EP Sbjct: 221 IQKHAQANGFSVVRSYCGHGIHKLF--HTAPNVPHYAKNKAVGVMKSGHVFTIEPMI 275 >4FUK-A nrPDB Length = 337 Score = 65.9 bits (159), Expect = 5e-11, Method: Composition-based stats. Identities = 49/239 (20%), Positives = 69/239 (28%), Gaps = 22/239 (9%) Query: 297 AVSETIPKDHRCCMPYTPICIAKA-VKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKG 355 VS + KD + I K +AE + IK L + K Sbjct: 38 GVSASEEKDRGSKVKVYNIQFLHDDSKKTAEIQR-----IKTVCQLSREVLDIATAAAKP 92 Query: 356 GVTEISAADKAEEFRRQQADFVDL----SFPTISSTGPNGAIIHYAPVPETNRTLSLDEV 411 G+T E ++ + FP T N I H P R L ++ Sbjct: 93 GITTDELDRIVHEATVERNMYPSPLNYYGFPKSVCTSVNEVICHGIPDS---RELEEGDI 149 Query: 412 YLIDSGAQYKDGTTDVTRTMHFGTPTAYEKECFTYVLKGHIAVSAAVFPTGTK---GHLL 468 ID + D+ T+ G P + A V P G + Sbjct: 150 LNIDVSSYLNGFHGDLNETVFIGRPDDDSVRLVHAAYECLCAGIGVVKPEALYKQVGDAI 209 Query: 469 DSFARSALWDSGLDYLHGTGHGVGSFLNVHEGPCGISYKTFSD-EPLEAGMIVTDEPGY 526 ++ A Y TGHGVG H P Y + G + T EP Sbjct: 210 EACASQYQCSVVRTY---TGHGVGHLF--HTSPTVCHYANNKSLGMMRPGHVFTIEPMI 263 >1XGN-A nrPDB Length = 295 Score = 62.8 bits (151), Expect = 4e-10, Method: Composition-based stats. Identities = 34/199 (17%), Positives = 63/199 (31%), Gaps = 15/199 (7%) Query: 330 MRRAHIKDAVALCELFNWLEKEVPKGGVTEISAADKAEEFRRQQADFVDLSFPTISSTGP 389 M + A + + ++ + G+ + A+ E+ + +FP S Sbjct: 1 MDTEKLMKAGEIAKKVREKAIKLARPGMLLLELAESIEKMIMELGG--KPAFPVNLSINE 58 Query: 390 NGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDVTRTMHFGTPTAYEKECFTYVLK 449 A HY P L + ID G D T+ G E E + Sbjct: 59 IAA--HYTPYKGDTTVLKEGDYLKIDVGVHIDGFIADTAVTVRVGM---EEDELMEAAKE 113 Query: 450 GHIAVSAAVFPTGTKGHLLDSFARSALWDSGLDYLHGTGHGVGSFLNVHEGPCGIS---- 505 + + +V G + L + + G + G + ++ GIS Sbjct: 114 A-LNAAISVARAGVEIKELGKAIENEIRKRGFKPIVNLS---GHKIERYKLHAGISIPNI 169 Query: 506 YKTFSDEPLEAGMIVTDEP 524 Y+ + L+ G + EP Sbjct: 170 YRPHDNYVLKEGDVFAIEP 188 >3S6B-A nrPDB Length = 368 Score = 61.7 bits (148), Expect = 9e-10, Method: Composition-based stats. Identities = 44/214 (20%), Positives = 70/214 (32%), Gaps = 18/214 (8%) Query: 321 VKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGGVTEISAADKAEEFRRQQADFVDL- 379 V N E + +R A I + + + GVT K EF + + Sbjct: 103 VNNEEEIQRIREACIL-GRKTLDYAH----TLVSPGVTTDEIDRKVHEFIIKNNAYPSTL 157 Query: 380 ---SFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDVTRTMHFGTP 436 FP T N + H P R L ++ ID YK +D+ T G Sbjct: 158 NYYKFPKSCCTSVNEIVCHGIPDY---RPLKSGDIINIDISVFYKGVHSDLNETYFVGDI 214 Query: 437 TAYEKECFTYVLKGHIAVSAAVF--PTGTKGHLLDSFARSALWDSGLDYLHG-TGHGVGS 493 KE V + ++ A+ G + + + + + +GHGVG Sbjct: 215 NDVPKEGKELVETCYFSLMEAIKKCKPGMFYKNIGTLIDAYVSKKNFSVVRSYSGHGVGK 274 Query: 494 FLNVHEGPCGISYKTFSD-EPLEAGMIVTDEPGY 526 H P +K ++ G + T EP Sbjct: 275 LF--HSNPTVPHFKKNKAVGIMKPGHVFTIEPMI 306 >4KM3-A nrPDB Length = 286 Score = 60.9 bits (146), Expect = 2e-09, Method: Composition-based stats. Identities = 46/240 (19%), Positives = 68/240 (28%), Gaps = 42/240 (17%) Query: 321 VKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGGVTEI-SAADKAEEFRRQQ----AD 375 +K++ E E M +A A L + ++ V V E K E F Q Sbjct: 4 LKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYVRRRCKEENFLPLQIGVDGA 63 Query: 376 FVDLSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDS--GA--------------- 418 +D + T S A + L ++ +D G Sbjct: 64 MMDYPYATCCSLNDEVA-----HAFPRHYILKDGDLLKVDMVLGGPIAKSDLNVSKLNFN 118 Query: 419 ----------QYKDGTTDVTRTMHFGTPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHLL 468 Y G D GTP+ K + G + Sbjct: 119 NVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDITKEAMYKGIEQAVVGNRIGDIG 178 Query: 469 DSFARSALWDSGLDYLHGT-GHGVGSFLNVHEGPCGISYK-TFSDEPLEAGMIVTDEPGY 526 + A G + GHGVG + HE P +Y L GM++T EP Sbjct: 179 AAIQEYA-ESRGYGVVRDLVGHGVGPTM--HEEPMVPNYGIAGRGLRLREGMVLTIEPMI 235 >3CB5-A nrPDB Length = 444 Score = 58.2 bits (139), Expect = 9e-09, Method: Composition-based stats. Identities = 45/282 (15%), Positives = 101/282 (35%), Gaps = 32/282 (11%) Query: 268 YKSILSELKALCADLS--PREKVWVSDKASYA-VSETIPKDHRCCMPYTPICIAKAVKNS 324 ++ I+ ++A + P++K + + E + + + A+K+ Sbjct: 121 FEKIIEYIRATNKKVGVFPKDKTQGKFINEWDSIFEPVKSEFNLVDASLGLAKCLAIKDE 180 Query: 325 AESEGMRRAHIKDAVALCELFNWLEKEV---PKGGVTEISAADKAEEFRRQQADFVDLS- 380 E ++ A + +VA+ + E +T +D+ E +A F S Sbjct: 181 QELANIKGAS-RVSVAVMSKYFVDELSTYIDQGKKITHSKFSDQMESLIDNEAFFQTKSL 239 Query: 381 -------------FPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDV 427 + I +G + + P T+ +V L G +YK ++V Sbjct: 240 KLGDIDLDQLEWCYTPIIQSGGSYDL---KPSAITDDRNLHGDVVLCSLGFRYKSYCSNV 296 Query: 428 TRTMHFGTPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHL---LDSFARSALWDSGLDYL 484 RT F + +K +++++ + G + + R+ D +++ Sbjct: 297 GRTYLFDPDSEQQKN-YSFLVALQKKLFEYCRDGAVIGDIYTKILGLIRAKRPDLEPNFV 355 Query: 485 HGTGHGVGSFLNVHEGPCGISYKTFSDEPLEAGMIVTDEPGY 526 G G+G + E ++ K + L+AGM + G+ Sbjct: 356 RNLGAGIG--IEFRESSLLVNAK--NPRVLQAGMTLNLSIGF 393 >5CE6-A nrPDB Length = 480 Score = 55.5 bits (132), Expect = 7e-08, Method: Composition-based stats. Identities = 45/220 (20%), Positives = 85/220 (38%), Gaps = 18/220 (8%) Query: 320 AVKNSAESEGMRRAHIKDA-------VALCELFNWLEKEVPKGGV---TEISAADKAEEF 369 A K++ E ++RA V E EK++ + TE D A+ Sbjct: 196 AAKSNEEITYIKRAAYLTGSVMKNFVVTKLENVIDEEKKILHSTLMEETEKVILDPAKVN 255 Query: 370 RRQQADFVDLSFPTISSTGPNGAIIHYAPVPETNRTLSLDE---VYLIDSGAQYKDGTTD 426 + +AD VD+ +P I +G + P +N + V + GA+YK ++ Sbjct: 256 CKLKADNVDICYPPIFQSGGKFDL---RPSAVSNDEALYYDSASVIICAVGARYKSYCSN 312 Query: 427 VTRTMHFGTPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSALWDSGLDYLHG 486 + RT + + + +LK AV ++ P G K A S + D + Sbjct: 313 IARTFLI-DADPIQSKAYEVLLKAQEAVIGSLKP-GNKLSAAYLAAVSVVEKDAPDMVSC 370 Query: 487 TGHGVGSFLNVHEGPCGISYKTFSDEPLEAGMIVTDEPGY 526 G+ + + G++ +D+ ++ GM+ G+ Sbjct: 371 LTKSAGTGIGIEFRESGLNINAKNDQIVKEGMVFNVSLGF 410 >5LYW-A nrPDB Length = 378 Score = 49.0 bits (115), Expect = 7e-06, Method: Composition-based stats. Identities = 38/188 (20%), Positives = 59/188 (31%), Gaps = 27/188 (14%) Query: 353 PKGGVTEISAADKAEEFRRQ----QADFVDLSFPTISSTGPNGAIIHYAPVPETNRTLSL 408 K G+T I +K E+ R+ L+FPT S N HY P L Sbjct: 81 IKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSL--NNCAAHYTPNAGDTTVLQY 138 Query: 409 DEVYLIDSGAQYKDGTTDVTRTMHFGTPTAYEKECFTYVLKGHIAVSAA-VFPTGT---- 463 D++ ID G D T+ T + +LK + + G Sbjct: 139 DDICKIDFGTHISGRIIDCAFTV---TFNPK----YDTLLKAVKDATNTGIKCAGIDVRL 191 Query: 464 --KGHLLDSFARSALWDSG-----LDYLHGT-GHGVGSFLNVHEGPCGISYKTFSDEPLE 515 G + S + + + GH +G + +H G K +E Sbjct: 192 CDVGEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQY-RIHAGKTVPIVKGGEATRME 250 Query: 516 AGMIVTDE 523 G + E Sbjct: 251 EGEVYAIE 258 >1QZY-A nrPDB Length = 478 Score = 49.0 bits (115), Expect = 7e-06, Method: Composition-based stats. Identities = 38/188 (20%), Positives = 59/188 (31%), Gaps = 27/188 (14%) Query: 353 PKGGVTEISAADKAEEFRRQ----QADFVDLSFPTISSTGPNGAIIHYAPVPETNRTLSL 408 K G+T I +K E+ R+ L+FPT S N HY P L Sbjct: 187 IKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSL--NNCAAHYTPNAGDTTVLQY 244 Query: 409 DEVYLIDSGAQYKDGTTDVTRTMHFGTPTAYEKECFTYVLKGHIAVSAA-VFPTGT---- 463 D++ ID G D T+ T + +LK + + G Sbjct: 245 DDICKIDFGTHISGRIIDCAFTV---TFNPK----YDTLLKAVKDATNTGIKCAGIDVRL 297 Query: 464 --KGHLLDSFARSALWDSG-----LDYLHGT-GHGVGSFLNVHEGPCGISYKTFSDEPLE 515 G + S + + + GH +G + +H G K +E Sbjct: 298 CDVGEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQY-RIHAGKTVPIIKGGEATRME 356 Query: 516 AGMIVTDE 523 G + E Sbjct: 357 EGEVYAIE 364 >3BIQ-A nrPDB Length = 467 Score = 46.7 bits (109), Expect = 3e-05, Method: Composition-based stats. Identities = 16/95 (16%), Positives = 34/95 (35%), Gaps = 3/95 (3%) Query: 374 ADFVDLSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDVTRTMHF 433 D +D ++ I +G + TN L + L G +Y + +++TRT Sbjct: 252 FDLLDWTYSPIIQSGKKFDL--RVSARSTNDQLYGNGCILASCGIRYNNYCSNITRTFLI 309 Query: 434 GTPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHLL 468 P+ + ++L + + G + Sbjct: 310 -DPSEEMANNYDFLLTLQKEIVTNILKPGRTPKEV 343 >5E5B-A nrPDB Length = 431 Score = 45.9 bits (107), Expect = 5e-05, Method: Composition-based stats. Identities = 36/242 (14%), Positives = 81/242 (33%), Gaps = 24/242 (9%) Query: 320 AVKNSAESEGMRRAHIKDAVALCELF--NWLEKEVPKGGVTEISAADKAEEFRRQQADF- 376 AVK E M++A + + F +E V A+ E+ ++ Sbjct: 172 AVKEDGELNLMKKAASITSEVFNKFFKERVMEIVDADEKVRHSKLAESVEKAIEEKKYLA 231 Query: 377 ------VDLSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDVTRT 430 V++ +P I +G N + + + G ++K +++ RT Sbjct: 232 GADPSTVEMCYPPIIQSGGNYNLKFSVVSDKNHMHFGA---ITCAMGIRFKSYCSNLVRT 288 Query: 431 MHFGTPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSALWDSGLDYLHGTGHG 490 + P+ +E + + L G K + + + + L+ Sbjct: 289 LMV-DPSQEVQENYNF-LLQLQEELLKELRHGVKICDVYNAVMDVVKKQKPELLNKITKN 346 Query: 491 VGSFLNVHEGPCGISYKTFSDEPLEAGMIVTDEPGYY----------EDGAFGIRIENVV 540 +G + + + + + L+ GM+ + G+ E+ + + I + V Sbjct: 347 LGFGMGIEFREGSLVINSKNQYKLKKGMVFSINLGFSDLTNKEGKKPEEKTYALFIGDTV 406 Query: 541 LV 542 LV Sbjct: 407 LV 408 >6A8M-A nrPDB Length = 461 Score = 44.0 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 19/121 (15%), Positives = 46/121 (38%), Gaps = 3/121 (2%) Query: 375 DFVDLSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDVTRTMHFG 434 +++D ++ I +GP + + L + L G +YK+ ++++RT Sbjct: 252 NYLDWAYSPIIQSGPKYDL--RVSARSSETQLDGNGCILASCGIRYKNYCSNISRTFLI- 308 Query: 435 TPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSALWDSGLDYLHGTGHGVGSF 494 P+ + + ++L + + G + A + + + G VGS Sbjct: 309 DPSDEMTDNYDFLLLLQEEIINNLLRVGATPKQIYDGAVNYINSKKPELSAGFTKNVGSL 368 Query: 495 L 495 + Sbjct: 369 M 369 >2V6C-A nrPDB Length = 353 Score = 40.5 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 21/114 (18%), Positives = 43/114 (37%), Gaps = 8/114 (7%) Query: 369 FRRQQADFVDLSFPTISSTGPNGAIIHYAPV-PETNRTLSLDEVYLIDSGAQYKDGTTDV 427 F++++ ++FPT S N + H++P+ + + L ++ ID G +V Sbjct: 57 FKKEKEMKKGIAFPTSISV--NNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANV 114 Query: 428 TRTMHFG--TPTAYEKECFTYVLKGHI---AVSAAVFPTGTKGHLLDSFARSAL 476 T G T + H+ A V P + +++ + A Sbjct: 115 AHTFVIGVAQGTQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAH 168 >2Q8K-A nrPDB Length = 401 Score = 38.6 bits (88), Expect = 0.008, Method: Composition-based stats. Identities = 20/114 (17%), Positives = 42/114 (36%), Gaps = 8/114 (7%) Query: 369 FRRQQADFVDLSFPTISSTGPNGAIIHYAPV-PETNRTLSLDEVYLIDSGAQYKDGTTDV 427 F++++ ++FPT S N + H++P+ + + L ++ ID G +V Sbjct: 71 FKKEKEMKKGIAFPTSISV--NNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANV 128 Query: 428 TRTM--HFGTPTAYEKECFTYVLKGHI---AVSAAVFPTGTKGHLLDSFARSAL 476 T T + H+ A V P + +++ + A Sbjct: 129 AHTFVVDVAQGTQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAH 182 >6F0K-D nrPDB Length = 217 Score = 32.0 bits (71), Expect = 0.89, Method: Composition-based stats. Identities = 19/72 (26%), Positives = 31/72 (43%), Gaps = 6/72 (8%) Query: 197 FVVTALDEIAWLFNLRGSDVEHNPVFFSYAIIGLETIMLFIDGDRID---APSVKEHLLL 253 + +AL +A + L G +NP+F+S + + F+ D P+ LL Sbjct: 125 ILFSALAGVATMLALNGLPRPYNPLFYSKNFMRVTDDGFFLFVAASDPKFDPTATRQLLE 184 Query: 254 DLGLEAEYRIQV 265 LG Y I+V Sbjct: 185 QLGG---YNIEV 193 >2FGT-A nrPDB Length = 417 Score = 31.2 bits (69), Expect = 1.3, Method: Composition-based stats. Identities = 52/328 (15%), Positives = 113/328 (34%), Gaps = 49/328 (14%) Query: 140 GHHLIPVKENLVDKIWTDRPERPCKPLLTLGLDYTGI---SWKDKVADLRLKMAERNVMW 196 G H L ++IW+D P K + + Y SW + K+ + Sbjct: 33 GAHYKVDDNALYEEIWSDLPHWDVKGIKDISDQYDKAGFKSWFYGIGGSEAKLDLQFSDT 92 Query: 197 FVVTALDEIAWLFNLRGSDVEHNPVFFSYAIIGLETIMLFIDGDRIDAPSVKEHLLLDLG 256 +D LF E++ F + +I +I S + L+L++ Sbjct: 93 I---PIDIFQTLFKWSNQSFEYS--SFDHILIPFNETK---ANKKIYLVSYSKQLILEVT 144 Query: 257 LEAEYRIQVHPYKSILSELKALCADLSPREKVWVSDKASYAVSETIPKDHRCCMPYTPIC 316 +E+ Y++I+++LK ++ +I +P P+ Sbjct: 145 VESAN------YRNIMNDLKNRQSN------------MPAFSLFSIGSKKEFLLPNKPLT 186 Query: 317 IAKA--VKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGGVTEISA-----------A 363 + K V S ++ ++A D + E N+ + V G++ + Sbjct: 187 MDKKEFVTESIKTNTFKQALFSDPSIVREDSNYNNRNVLTDGISRLDVNLSQRQVQFQQR 246 Query: 364 DKAEEFRRQQADFVDLSFPTISSTGPNGAIIHYAPVPETNRT-----LSLDEVYLIDSGA 418 + + Q + + S + TG HY + + +D++ +I+S A Sbjct: 247 NLVQSTSYQTGELIKKSQKYLEDTG--SWTDHYQFFNINDSQQLSFYIFMDQIPVINSTA 304 Query: 419 QYKDGTTDVTRTMHFGTPTAYEKECFTY 446 + T+ +T +Y++ ++ Sbjct: 305 KPFGATSAITVQWANDDILSYKRPNYSL 332 >1V0D-A nrPDB Length = 329 Score = 30.9 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 9/71 (12%), Positives = 23/71 (32%), Gaps = 3/71 (4%) Query: 408 LDEVYLIDSGAQYKDGTTDVTRTMHFGTPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHL 467 E+ L+ +G + +D+TR + + ++ A L Sbjct: 69 DAELLLLTAGETWHGYVSDITRFLSV--FNEPHAGVIQAA-RQQLSDEQAPLRQKLLADL 125 Query: 468 LDSFARSALWD 478 L +++ + Sbjct: 126 LHHVSQNITAE 136 >1H78-A nrPDB Length = 605 Score = 30.5 bits (67), Expect = 2.6, Method: Composition-based stats. Identities = 12/51 (23%), Positives = 26/51 (50%), Gaps = 1/51 (1%) Query: 516 AGMIVTDEPGYYEDGAFGIRIE-NVVLVVPVKTKYNFNNRGSLTFEPLTLV 565 G+ T P Y++GAFG+R++ + ++ K + + G + L ++ Sbjct: 360 KGVKATVAPILYQEGAFGVRLKPDDDIIELFKNGRSSVSLGYIGIHELNIL 410 >4ADY-A nrPDB Length = 963 Score = 30.1 bits (66), Expect = 3.1, Method: Composition-based stats. Identities = 12/55 (21%), Positives = 23/55 (41%), Gaps = 1/55 (1%) Query: 17 MRNSEYVTEPIQAYIIPSGDAHQSEYIA-PCDCRRAFVSGFDGSAGTAIITEEHA 70 ++Y ++P + + QS YI+ D R V F G+ G ++ + Sbjct: 867 FYKNKYSSKPYKVDNMTRILPQQSRYISFIKDDRFVPVRKFKGNNGVVVLRDREP 921 >3CLH-A nrPDB Length = 343 Score = 29.7 bits (65), Expect = 3.4, Method: Composition-based stats. Identities = 19/64 (29%), Positives = 27/64 (42%), Gaps = 13/64 (20%) Query: 479 SGLDYLHGTGHGVGSFLN----VHEGPCGISYKTFSDEPLEAGMIVTDEPGYYEDGAFGI 534 +GL+Y H GH + + +H I + +D L GM+ E YE Sbjct: 225 AGLNYGHTFGHAIEKETDYERFLHGEAIAIGMRMANDLALSLGMLTLKE---YE------ 275 Query: 535 RIEN 538 RIEN Sbjct: 276 RIEN 279 >5YK0-A nrPDB Length = 452 Score = 29.7 bits (65), Expect = 3.7, Method: Composition-based stats. Identities = 22/173 (12%), Positives = 46/173 (26%), Gaps = 16/173 (9%) Query: 322 KNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGGVTEISAADKAEEFRRQQADFVDLSF 381 K + + H+ + + W+E + EI E+ +L+F Sbjct: 224 KAYHDHPRFQVPHVVASAPKVVIQEWIEG----VPMAEIIRHGTTEQRDLIGTLLAELTF 279 Query: 382 PTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGA---QYKDGTTDVTRTMHFGTPTA 438 ++H P L + +ID GA ++ T+ Sbjct: 280 D----APRRLGLMHGDAHPGNFMLLPDGRMGIIDFGAVAPMPGGFPIELGMTIRLAREKN 335 Query: 439 YEKECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSALWDSGLDYLHGTGHGV 491 + +L +D R + ++ H T + Sbjct: 336 -----YDLLLPTMEKAGLIQRGRQVSVREIDEMLRQYVEPIQVEVFHYTRKWL 383 >5APN-x nrPDB Length = 616 Score = 29.3 bits (64), Expect = 5.0, Method: Composition-based stats. Identities = 10/39 (25%), Positives = 15/39 (38%), Gaps = 1/39 (2%) Query: 405 TLSLDEVYLIDSGAQYKDGTTDVTRTMHFGTPTAYEKEC 443 TL ++ I G T++V+ TM P K Sbjct: 155 TLRPGDLVKITLGVHIDGYTSEVSHTMVI-YPVDETKPI 192 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.129 0.335 Lambda K H 0.267 0.0392 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 22,952,164 Number of Sequences: 36641 Number of extensions: 912626 Number of successful extensions: 2530 Number of sequences better than 10.0: 57 Number of HSP's better than 10.0 without gapping: 57 Number of HSP's successfully gapped in prelim test: 35 Number of HSP's that attempted gapping in prelim test: 2291 Number of HSP's gapped (non-prelim): 105 length of query: 623 length of database: 10,336,785 effective HSP length: 103 effective length of query: 520 effective length of database: 6,562,762 effective search space: 3412636240 effective search space used: 3412636240 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 62 (28.6 bits)