BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9NQ88 (270 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3DCY-A nrPDB 558 e-160 3E9D-A nrPDB 183 6e-47 4EMB-A nrPDB 71 4e-13 4ODI-A nrPDB 64 1e-10 3GW8-A nrPDB 63 1e-10 3KKK-A nrPDB 62 3e-10 1FZT-A nrPDB 61 5e-10 4PZA-A nrPDB 60 7e-10 3R7A-A nrPDB 58 5e-09 5VVE-A nrPDB 57 7e-09 1E58-A nrPDB 54 8e-08 3D8H-A nrPDB 53 1e-07 4EO9-A nrPDB 51 5e-07 5PGM-D nrPDB 50 9e-07 5UM0-A nrPDB 50 1e-06 3PGM-A nrPDB 49 3e-06 3NFY-A nrPDB 47 1e-05 3LG2-A nrPDB 46 2e-05 5Y64-B nrPDB 40 0.001 6NRU-A nrPDB 38 0.004 4IJ6-A nrPDB 34 0.064 2WV9-A nrPDB 33 0.097 5HR5-A nrPDB 31 0.57 5HTK-A nrPDB 31 0.65 1YSC-A nrPDB 30 0.90 3CF4-A nrPDB 29 1.8 4AC9-A nrPDB 28 3.0 4QS9-A nrPDB 28 3.6 >3DCY-A nrPDB Length = 275 Score = 558 bits (1439), Expect = e-160, Method: Compositional matrix adjust. Identities = 269/269 (100%), Positives = 269/269 (100%) Query: 2 ARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNVKFTHAFSSDLMR 61 ARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNVKFTHAFSSDLMR Sbjct: 7 ARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNVKFTHAFSSDLMR 66 Query: 62 TKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVFTPPG 121 TKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVFTPPG Sbjct: 67 TKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVFTPPG 126 Query: 122 GETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKNHSSKVN 181 GETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKNHSSKVN Sbjct: 127 GETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKNHSSKVN 186 Query: 182 SDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPNTGMSLFIIN 241 SDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPNTGMSLFIIN Sbjct: 187 SDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPNTGMSLFIIN 246 Query: 242 FEEGREVKPTVQCICMNLQDHLNGLTETR 270 FEEGREVKPTVQCICMNLQDHLNGLTETR Sbjct: 247 FEEGREVKPTVQCICMNLQDHLNGLTETR 275 >3E9D-A nrPDB Length = 265 Score = 183 bits (465), Expect = 6e-47, Method: Compositional matrix adjust. Identities = 106/265 (40%), Positives = 152/265 (57%), Gaps = 17/265 (6%) Query: 1 MARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNVKFTHAFSSDLM 60 M FALT+VRHGET++N++K++QGQG+D PLS+TG +QAAAAG +L ++ FT+ F S+L Sbjct: 1 MLTFALTIVRHGETQYNRDKLLQGQGIDTPLSDTGHQQAAAAGRYLKDLHFTNVFVSNLQ 60 Query: 61 RTKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVFTPP 120 R QT IL + + D LRER +GV EG+ L+ MA AA + C +TPP Sbjct: 61 RAIQTAEIILGNNLHSSATEMILDPLLRERGFGVAEGRPKEHLKNMANAAGQSCRDYTPP 120 Query: 121 GGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKNHSSKV 180 GGETL+QVK R F FL L + ++ PS + +A + Sbjct: 121 GGETLEQVKTR---FKMFLKSLFQRMFEEHGSALSSVPSEADQPVIAGL----------- 166 Query: 181 NSDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPNTGMSLFI- 239 +D G + L+VSHGA++R + + DL+C LPA L +++ S PNTG+S FI Sbjct: 167 -ADDGAQNVPVHALMVSHGAFIRISVRHLVEDLQCCLPAGLKMNQVFSPCPNTGISRFIF 225 Query: 240 -INFEEGREVKPTVQCICMNLQDHL 263 I+ EE +Q + +N +DHL Sbjct: 226 TIHREESVLRATRIQGVFINRKDHL 250 >4EMB-A nrPDB Length = 274 Score = 71.2 bits (173), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 70/255 (27%), Positives = 115/255 (45%), Gaps = 42/255 (16%) Query: 4 FALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNN--VKFTHAFSSDLMR 61 + L +VRHGE+ +NKE + G D LS+ G +A AG+ L F AFSS L R Sbjct: 28 YKLVLVRHGESEWNKENLFTGW-TDVKLSDKGIDEAVEAGLLLKQEGYSFDIAFSSLLSR 86 Query: 62 TKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVF---- 117 T++ IL R ++VK RL ER YG ++G L++ AK ++ ++ Sbjct: 87 ANDTLNIIL-RELGQSYISVKKTWRLNERHYGALQG--LNKSETAAKYGEDKVLIWRRSY 143 Query: 118 -TPPGGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSN-CLETSLAEIFPLGKN 175 PP +LD+ R +K+ K + PS CL+ ++A + P + Sbjct: 144 DVPP--MSLDESDDRH----------PIKDPRYKHIPKRELPSTECLKDTVARVIPYWTD 191 Query: 176 HSSKVNSDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPNTGM 235 +K + V+V +HG +R+L YF LS +++ + TG+ Sbjct: 192 EIAKEVLE------GKKVIVAAHGNSLRALVKYF---------DNLSEEDVLKLNIPTGI 236 Query: 236 SLFIINFEEGREVKP 250 L +E +++ P Sbjct: 237 PLV---YELDKDLNP 248 >4ODI-A nrPDB Length = 281 Score = 63.5 bits (153), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 60/219 (27%), Positives = 100/219 (45%), Gaps = 36/219 (16%) Query: 2 ARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQA--AAAGIFLNNVKFTHAFSSDL 59 A++ L ++RHGE+ +NKE G D PLS G ++A AA + +F A++S L Sbjct: 17 AKYTLVLIRHGESTWNKENRFTGW-TDVPLSPVGEQEAVEAAKALKEKGFEFDVAYTSVL 75 Query: 60 MRTKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVF-- 117 R T +L+ + C + VK RL ER YG ++G L++ AK E+ ++ Sbjct: 76 QRAVVTCWTVLKGTDMCH-IPVKSSWRLNERHYGALQG--LNKAETAAKHGDEQVKIWRR 132 Query: 118 ----TPPGGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSP-SNCLETSLAEIFPL 172 PP E D+ + G D + +++ EA P + CL+ ++ + P Sbjct: 133 SYDIPPPPLEKSDK-RWPGND---AVYKMVPNEA---------LPLTECLKDTVERVLPF 179 Query: 173 GKNHSSKVNSDSGIPGL--AASVLVVSHGAYMRSLFDYF 209 +H + P + VLV +HG +R L + Sbjct: 180 WFDHIA--------PSIMEGKRVLVAAHGNSLRGLVKHL 210 >3GW8-A nrPDB Length = 257 Score = 63.2 bits (152), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 58/216 (26%), Positives = 97/216 (44%), Gaps = 34/216 (15%) Query: 4 FALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNVKFTH--AFSSDLMR 61 + L ++RHGE+ +NKE G VD L+E G ++A AG L +T A++S L R Sbjct: 10 YKLVLIRHGESTWNKENRFTGW-VDVDLTEQGNREARQAGQLLKEAGYTFDIAYTSVLKR 68 Query: 62 TKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVF---- 117 +T+ + ++ + V + RL ER YG + G L++ AK E+ V+ Sbjct: 69 AIRTLWHVQDQMDLMY-VPVVHSWRLNERHYGALSG--LNKAETAAKYGDEQVLVWRRSY 125 Query: 118 --TPPGGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKN 175 PP E D+ + + +EQ + CL+ ++A + PL Sbjct: 126 DTPPPALEPGDERAPYADPRYAKV---------PREQLPL---TECLKDTVARVLPLW-- 171 Query: 176 HSSKVNSDSGIPGLAA--SVLVVSHGAYMRSLFDYF 209 ++S P + A VL+ +HG +R+L Y Sbjct: 172 ------NESIAPAVKAGKQVLIAAHGNSLRALIKYL 201 >3KKK-A nrPDB Length = 258 Score = 61.6 bits (148), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 66/259 (25%), Positives = 114/259 (44%), Gaps = 44/259 (16%) Query: 1 MARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFL--NNVKFTHAFSSD 58 M + L ++RHGE+ +NKE G D PLSE G ++A AAG +L N KF ++S Sbjct: 9 MTTYTLVLLRHGESTWNKENKFTGW-TDVPLSEKGEEEAIAAGKYLKEKNFKFDVVYTSV 67 Query: 59 LMRTKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVF- 117 L R T +L+ + VK RL ER G ++G L++ K E+ ++ Sbjct: 68 LKRAICTAWNVLKTADLLHVPVVK-TWRLNERHCGSLQG--LNKSETAKKYGEEQVKIWR 124 Query: 118 ----TPPGGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLG 173 PP + + G + + + K+A F++ CL+ ++ + P Sbjct: 125 RSYDIPPPKLDKEDNRWPG---HNVVYKNVPKDA---LPFTE-----CLKDTVERVLPFW 173 Query: 174 KNHSSKVNSDSGIPGLAAS--VLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTP 231 +H + P + A+ V+V +HG +R L + LS ++++ + Sbjct: 174 FDHIA--------PDILANKKVMVAAHGNSLRGLVKHL---------DNLSEADVLELNI 216 Query: 232 NTGMSLFIINFEEGREVKP 250 TG+ L +E +KP Sbjct: 217 PTGVPLV---YELDENLKP 232 >1FZT-A nrPDB Length = 211 Score = 61.2 bits (147), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 47/140 (33%), Positives = 71/140 (50%), Gaps = 12/140 (8%) Query: 6 LTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNN--VKFTHAFSSDLMRTK 63 L + RHGE+ +NK + G D LSETG K+A G L + KF AF+S L R + Sbjct: 10 LVLTRHGESEWNKLNLFTGWK-DPALSETGIKEAKLGGERLKSRGYKFDIAFTSALQRAQ 68 Query: 64 QTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVF------ 117 +T ILE T+K + +L ER YG ++G L++ A K E+ ++ Sbjct: 69 KTCQIILEEVGEPNLETIKSE-KLNERYYGDLQG--LNKDDARKKWGAEQVQIWRRSYDI 125 Query: 118 TPPGGETLDQVKMRGIDFFE 137 PP GE+L R + +++ Sbjct: 126 APPNGESLKDTAERVLPYYK 145 >4PZA-A nrPDB Length = 223 Score = 60.5 bits (145), Expect = 7e-10, Method: Compositional matrix adjust. Identities = 46/129 (35%), Positives = 63/129 (48%), Gaps = 8/129 (6%) Query: 6 LTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNVKFTHAFSSDLMRTKQT 65 L ++RHG+T +N +QGQ +D LSE G QA AA L + SSDL R T Sbjct: 6 LVMLRHGQTDYNVGSRMQGQ-LDTELSELGRTQAVAAAEVLGKRQPLLIVSSDLRRAYDT 64 Query: 66 MHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAR---EECPVFTPPGG 122 + ER+ V+ D+RLRE G +G +++ A A AR E + P GG Sbjct: 65 AVKLGERTGLV----VRVDTRLRETHLGDWQGLTHAQIDADAPGARLAWREDATWAPHGG 120 Query: 123 ETLDQVKMR 131 E+ V R Sbjct: 121 ESRVDVAAR 129 >3R7A-A nrPDB Length = 237 Score = 57.8 bits (138), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 39/111 (35%), Positives = 59/111 (53%), Gaps = 3/111 (2%) Query: 6 LTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNVKFTHAFSSDLMRTKQT 65 L V RHG+T N QG D PL E G + A G L ++ F +A+SSD R +T Sbjct: 16 LYVTRHGKTILNTNHRAQGWA-DSPLVEKGVEVATNLGTGLKDIHFMNAYSSDSGRAIET 74 Query: 66 MHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELR-AMAKAAREECP 115 + +L+ S+ K + ++ +LRE +G+ EG+ L + A+ KAA P Sbjct: 75 ANLVLKYSEQSK-LKLEQRKKLRELNFGIFEGEKLDNMWDAVGKAAGVTSP 124 >5VVE-A nrPDB Length = 258 Score = 57.4 bits (137), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 66/255 (25%), Positives = 110/255 (43%), Gaps = 42/255 (16%) Query: 4 FALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFL--NNVKFTHAFSSDLMR 61 + L ++RHGE+ +NKE G D LSETG K+A AG L +F ++S L R Sbjct: 11 YKLVLIRHGESEWNKENKFTG-WYDCGLSETGLKEAKEAGEILLKEGYEFDLCYTSFLKR 69 Query: 62 TKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVF---- 117 +T+ LE VK+ RL ER YG ++G L++ + K E+ ++ Sbjct: 70 AIKTLWIALETMDAMYLPVVKH-WRLNERHYGALQG--LNKTQTAEKHGEEQVKIWRRSY 126 Query: 118 --TPPGGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKN 175 PP E D+ ++ L Q E+ + + L+ ++ + P Sbjct: 127 DIPPPALEVTDERYPGHERKYQGLTQ---------EELPK---TESLKLTVDRVLP---- 170 Query: 176 HSSKVNSDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPNTGM 235 + + V + S G VL+ +HG +R+L Y +S E++ + TG+ Sbjct: 171 YWNDVIAPSVKEG--KRVLIAAHGNSLRALVKYL---------DNISEEEIVELNIPTGV 219 Query: 236 SLFIINFEEGREVKP 250 L +E +KP Sbjct: 220 PLV---YELDENLKP 231 >1E58-A nrPDB Length = 249 Score = 53.5 bits (127), Expect = 8e-08, Method: Compositional matrix adjust. Identities = 64/249 (25%), Positives = 106/249 (42%), Gaps = 44/249 (17%) Query: 6 LTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNN--VKFTHAFSSDLMRTK 63 L +VRHGE+++NKE G D LSE G +A AAG L F A++S L R Sbjct: 5 LVLVRHGESQWNKENRFTGW-YDVDLSEKGVSEAKAAGKLLKEEGYSFDFAYTSVLKRAI 63 Query: 64 QTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVF------ 117 T+ +L+ + V+ +L ER YG ++G L++ K E+ + Sbjct: 64 HTLWNVLDELDQAW-LPVEKSWKLNERHYGALQG--LNKAETAEKYGDEQVKQWRRGFAV 120 Query: 118 TPPGGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKNHS 177 TPP T D + G D +L KE E L ++ + P Sbjct: 121 TPPEL-TKDDERYPGHD--PRYAKLSEKELPLTE---------SLALTIDRVIPYW---- 164 Query: 178 SKVNSDSGIPGLAAS--VLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPNTGM 235 +++ +P + + V++ +HG +R+L Y +S E++ + TG+ Sbjct: 165 ----NETILPRMKSGERVIIAAHGNSLRALVKYL---------DNMSEEEILELNIPTGV 211 Query: 236 SLFIINFEE 244 L + F+E Sbjct: 212 PL-VYEFDE 219 >3D8H-A nrPDB Length = 267 Score = 53.1 bits (126), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 65/217 (29%), Positives = 97/217 (44%), Gaps = 35/217 (16%) Query: 4 FALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFL--NNVKFTHAFSSDLMR 61 + LT++RHGE+ +NKE G D LSE G +A AG L KF ++S L R Sbjct: 21 YKLTLIRHGESEWNKENRFTGW-TDVSLSEQGVSEAIEAGRMLLEKGFKFDVVYTSVLKR 79 Query: 62 TKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVFTPPG 121 T +L+ + + RL ER YG ++G SE + Sbjct: 80 AIMTTWTVLKELGNINCPIINH-WRLNERHYGALQGLNKSETASKF-------------- 124 Query: 122 GETLDQVKM--RGIDFFEFLCQLILKEADQK----EQFSQGSPSNCLETS--LAEIFPLG 173 GE DQVK+ R D + +L+++D + E +G +CL T+ L + Sbjct: 125 GE--DQVKIWRRSFD----VPPPVLEKSDPRWPGNELIYKGICPSCLPTTECLKDTVERV 178 Query: 174 KNHSSKVNSDSGIPGLAASVLVVSHGAYMRSLFDYFL 210 K + V + S + G SVLV +HG +R+L Y L Sbjct: 179 KPYFEDVIAPSIMSG--KSVLVSAHGNSLRALL-YLL 212 >4EO9-A nrPDB Length = 268 Score = 51.2 bits (121), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 65/259 (25%), Positives = 113/259 (43%), Gaps = 52/259 (20%) Query: 6 LTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFL--NNVKFTHAFSSDLMRTK 63 L ++RHGE+ +N + G VD L++ G +A +G L +N+ ++S L R Sbjct: 30 LILLRHGESDWNARNLFTGW-VDVGLTDKGRAEAVRSGELLAEHNLLPDVLYTSLLRRAI 88 Query: 64 QTMHGILERSKFCKDMTVKYDSRLRERKYGVVEG--KALS-----ELRAMAKAAREECPV 116 T H L+ + + + V+ RL ER YG ++G KA++ E R MA + P Sbjct: 89 TTAHLALDTADWLW-IPVRRSWRLNERHYGALQGLDKAVTKARYGEERFMAWRRSYDTP- 146 Query: 117 FTPPGGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSP-SNCLETSLAEIFPLGKN 175 PP E +G +F + +AD + G P + CL + P Sbjct: 147 --PPPIE-------KGSEFSQ--------DADPRYTDIGGGPLTECLADVVTRFLP---- 185 Query: 176 HSSKVNSDSGIPGL--AASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPNT 233 +D +P L +VL+V+HG +R+L + +S E++ + T Sbjct: 186 ----YFTDVIVPDLRTGRTVLIVAHGNSLRALVKHL---------DEMSDDEVVGLNVPT 232 Query: 234 GMSLFIINFEEGREVKPTV 252 G+ L ++ +++P V Sbjct: 233 GIPL---RYDLDADLRPVV 248 >5PGM-D nrPDB Length = 246 Score = 50.1 bits (118), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 60/261 (22%), Positives = 112/261 (42%), Gaps = 42/261 (16%) Query: 6 LTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNVKFTHA--FSSDLMRTK 63 L +VRHG++ +N++ + G VD LS G ++AA AG L K ++S L R Sbjct: 3 LVLVRHGQSEWNEKNLFTGW-VDVKLSAKGQQEAARAGELLKEKKVYPDVLYTSKLSRAI 61 Query: 64 QTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVF------ 117 QT + LE++ + V RL ER YG ++GK +E + K E+ + Sbjct: 62 QTANIALEKADRLW-IPVNRSWRLNERHYGDLQGKDKAE--TLKKFGEEKFNTYRRSFDV 118 Query: 118 TPPGGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKNHS 177 PP + +G + ++++ +L E + L + + P ++ Sbjct: 119 PPPPIDASSPFSQKGDERYKYVDPNVLPETE------------SLALVIDRLLPYWQDVI 166 Query: 178 SKVNSDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPNTGMSL 237 +K + SG +V++ +HG +R L + +S +++ + TG+ L Sbjct: 167 AK-DLLSG-----KTVMIAAHGNSLRGLVKHL---------EGISDADIAKLNIPTGIPL 211 Query: 238 FIINFEEGREVKPTVQCICMN 258 FE +KP+ ++ Sbjct: 212 V---FELDENLKPSKPSYYLD 229 >5UM0-A nrPDB Length = 235 Score = 50.1 bits (118), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 36/94 (38%), Positives = 51/94 (54%), Gaps = 4/94 (4%) Query: 6 LTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFL--NNVKFTHAFSSDLMRTK 63 L +RHG++ +N + + G D LSE G +AAAAG L N +F AF+S L R Sbjct: 11 LVFIRHGQSEWNAKNLFTGWR-DVKLSEQGLAEAAAAGKKLKENGYEFDIAFTSVLTRAI 69 Query: 64 QTMHGILERSKFCKDMTVKYDSRLRERKYGVVEG 97 +T + +LE S +K RL ER YG ++G Sbjct: 70 KTCNIVLEESDQLFVPQIK-TWRLNERHYGRLQG 102 >3PGM-A nrPDB Length = 244 Score = 48.9 bits (115), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 34/95 (35%), Positives = 51/95 (53%), Gaps = 4/95 (4%) Query: 6 LTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNN--VKFTHAFSSDLMRTK 63 L +VRHG++ +N++ + G VD LS G ++AA AG L V ++S L R Sbjct: 3 LVLVRHGQSEWNEKNLFTGW-VDVKLSAKGQQEAARAGELLKEKGVNVLVDYTSKLSRAI 61 Query: 64 QTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGK 98 QT + LE++ + V RL ER YG ++GK Sbjct: 62 QTANIALEKADRLW-IPVNRSWRLNERHYGDLQGK 95 >3NFY-A nrPDB Length = 267 Score = 47.0 bits (110), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 62/259 (23%), Positives = 106/259 (40%), Gaps = 37/259 (14%) Query: 1 MARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLN--NVKFTHAFSSD 58 M+++ L ++RHGE +NKE VD+ L+ G ++A G L N +F F+S Sbjct: 1 MSKYKLIMLRHGEGAWNKENRF-CSWVDQKLNSEGMEEARNCGKQLKALNFEFDLVFTSV 59 Query: 59 LMRTKQTMHGILERSKFCKDMTVKYDSRLRERKYGVV-----EGKALSELRAMAKAAREE 113 L R+ T ILE + + V+ RL ER YG + E AL+ + R Sbjct: 60 LNRSIHTAWLILEELG-QEWVPVESSWRLNERHYGALIGLNREQMALNHGEEQVRLWRRS 118 Query: 114 CPVFTPPGGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLG 173 V PP E+ + D +C + L + + E L+ L + P Sbjct: 119 YNVTPPPIEESHPYYQEIYNDRRYKVCDVPLDQLPRSE---------SLKDVLERLLPYW 169 Query: 174 KNHSSKVNSDSGIPGL--AASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTP 231 + P + ++L+ +HG R+L + +S +++++T Sbjct: 170 NERIA--------PEVLRGKTILISAHGNSSRALLKHL---------EGISDEDIINITL 212 Query: 232 NTGMSLFIINFEEGREVKP 250 TG+ + + E R V P Sbjct: 213 PTGVPILLELDENLRAVGP 231 >3LG2-A nrPDB Length = 292 Score = 46.2 bits (108), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 56/215 (26%), Positives = 85/215 (39%), Gaps = 62/215 (28%) Query: 8 VVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAG-------IFLNNVKFTHAFSSDLM 60 +VRHG+T ++K G D PL+ G Q G FLN T+ F+S + Sbjct: 31 IVRHGQTEWSKSGQYTGL-TDLPLTPYGEGQMLRTGESVFRNNQFLNPDNITYIFTSPRL 89 Query: 61 RTKQTMHGIL------ERSKFCKDMTVKYDSRLRERKYGVVEG---KALSELRAMAKAAR 111 R +QT+ +L +R+K + V D LRE +YG EG + + ELR + Sbjct: 90 RARQTVDLVLKPLSDEQRAK----IRVVVDDDLREWEYGDYEGMLTREIIELRKSRGLDK 145 Query: 112 EECPVFTPPG---GETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAE 168 E G GET Q+ +R L ++A Sbjct: 146 ERPWNIWRDGCENGETTQQIGLR------------------------------LSRAIAR 175 Query: 169 IFPLGKNHSSKVNSDSGIPGLAASVLVVSHGAYMR 203 I L + H S+ G A+ ++V +HG +R Sbjct: 176 IQNLHRKHQSE--------GRASDIMVFAHGHALR 202 >5Y64-B nrPDB Length = 262 Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust. Identities = 34/119 (28%), Positives = 55/119 (46%), Gaps = 6/119 (5%) Query: 1 MARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNV--KFTHAFSSD 58 MA + L ++RHGE+ +N E G D LS G ++A G L + +F F+S Sbjct: 1 MAAYKLVLIRHGESAWNLENRFSGW-YDADLSPAGHEEAKRGGQALRDAGYEFDICFTSV 59 Query: 59 LMRTKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVF 117 R +T+ +L+ + V RL ER YG + G L++ AK + ++ Sbjct: 60 QKRAIRTLWTVLDAIDQMW-LPVVRTWRLNERHYGGLTG--LNKAETAAKHGEAQVKIW 115 >6NRU-A nrPDB Length = 206 Score = 38.1 bits (87), Expect = 0.004, Method: Compositional matrix adjust. Identities = 21/65 (32%), Positives = 33/65 (50%), Gaps = 1/65 (1%) Query: 6 LTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNVKFTHAFSSDLMRTKQT 65 L ++RHGET+ N + + G PL+ G +QA L++V F S+L R + T Sbjct: 6 LWLIRHGETQANVDGLYSGHA-PTPLTARGIEQAQNLHTLLDDVSFDLVLCSELERAQHT 64 Query: 66 MHGIL 70 +L Sbjct: 65 ARLVL 69 >4IJ6-A nrPDB Length = 211 Score = 34.3 bits (77), Expect = 0.064, Method: Compositional matrix adjust. Identities = 42/138 (30%), Positives = 58/138 (42%), Gaps = 13/138 (9%) Query: 6 LTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNVKFTHAFSSDLMRTKQT 65 L +VR E+ +N QG +D LSE G KQA L+ +SS L RT T Sbjct: 4 LILVRAAESEWNPVGRYQGL-LDPDLSERGKKQAKLLAQELSREHLDVIYSSPLKRTYLT 62 Query: 66 MHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVFTPP----- 120 I E K++ V + R+ E +G+ G + E+ M K + P Sbjct: 63 ALEIAE----AKNLEVIKEDRIIEIDHGMWSGMLVEEV--MEKYPEDFRRWVEEPHKVEF 116 Query: 121 -GGETLDQVKMRGIDFFE 137 GGE+L V R F E Sbjct: 117 QGGESLASVYNRVKGFLE 134 >2WV9-A nrPDB Length = 673 Score = 33.5 bits (75), Expect = 0.097, Method: Compositional matrix adjust. Identities = 27/91 (29%), Positives = 45/91 (49%), Gaps = 12/91 (13%) Query: 121 GGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEI------FPLGK 174 G LDQ K G+D Q+I+ E + Q P +T+ EI +P+G Sbjct: 135 GPWKLDQ-KWNGVDD----VQMIVVEPGKPAINVQTKPG-IFKTAHGEIGAVSLDYPIGT 188 Query: 175 NHSSKVNSDSGIPGLAASVLVVSHGAYMRSL 205 + S VNS+ I GL + +++ +GAY+ ++ Sbjct: 189 SGSPIVNSNGEIIGLYGNGVILGNGAYVSAI 219 >5HR5-A nrPDB Length = 531 Score = 30.8 bits (68), Expect = 0.57, Method: Compositional matrix adjust. Identities = 55/219 (25%), Positives = 78/219 (35%), Gaps = 65/219 (29%) Query: 6 LTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNVKFT--HAFSSDLMRTK 63 + + RHGE+ FN ++ G D LS G + A A FL + ++S L RT Sbjct: 253 IYLCRHGESEFN---LLGKIGGDSGLSVRGKQFAQALRKFLEEQEIADLKVWTSQLKRTI 309 Query: 64 QTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAK---AAR-EECPVFTP 119 QT + +T + L E GV E +E++ A R EE ++ Sbjct: 310 QTAESL--------GVTYEQWKILNEIDAGVCEEMTYAEIQEQYPDEFALRDEEKYLYRY 361 Query: 120 PGGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKNHSSK 179 PGGE+ + R LE + E+ G Sbjct: 362 PGGESYQDLVQR------------------------------LEPVIMELERQG------ 385 Query: 180 VNSDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLP 218 +VLV+SH A MR L YFL LP Sbjct: 386 ------------NVLVISHQAVMRCLLAYFLDKGADELP 412 >5HTK-A nrPDB Length = 505 Score = 30.8 bits (68), Expect = 0.65, Method: Compositional matrix adjust. Identities = 54/220 (24%), Positives = 78/220 (35%), Gaps = 65/220 (29%) Query: 5 ALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNVKFT--HAFSSDLMRT 62 + + RHGE+ FN ++ G D LS G + A A FL + T ++S L RT Sbjct: 251 TIYLCRHGESEFN---LLGKIGGDSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRT 307 Query: 63 KQTMHGI---LERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAR-EECPVFT 118 QT + E+ K ++ E Y +E + E A R +E ++ Sbjct: 308 IQTAESLGVPYEQWKILNEIDA---GVCEEMTYAEIEKRYPEEF-----ALRDQEKYLYR 359 Query: 119 PPGGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKNHSS 178 PGGE+ + R LE + E+ G Sbjct: 360 YPGGESYQDLVQR------------------------------LEPVIMELERQG----- 384 Query: 179 KVNSDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLP 218 +VLV+SH A MR L YFL LP Sbjct: 385 -------------NVLVISHQAVMRCLLAYFLDKGADELP 411 >1YSC-A nrPDB Length = 421 Score = 30.4 bits (67), Expect = 0.90, Method: Compositional matrix adjust. Identities = 11/40 (27%), Positives = 22/40 (55%) Query: 4 FALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAG 43 FA ++ H + FN ++ G G+ +PL++ + + A G Sbjct: 155 FASEILSHKDRNFNLTSVLIGNGLTDPLTQYNYYEPMACG 194 >3CF4-A nrPDB Length = 807 Score = 29.3 bits (64), Expect = 1.8, Method: Compositional matrix adjust. Identities = 18/58 (31%), Positives = 31/58 (53%), Gaps = 7/58 (12%) Query: 198 HGAYMRSLFDYFLTDLKCSLPATLSRSELMS--VTPNTGMSLFIINFEEGREVKPTVQ 253 H A+ R L D+ + LP TL +S +++ +T +TG+S + EVKP ++ Sbjct: 117 HAAHGRHLLDHLIEKYGEDLPLTLGQSNVLTPNITISTGLSPKTLG-----EVKPAME 169 >4AC9-A nrPDB Length = 482 Score = 28.5 bits (62), Expect = 3.0, Method: Compositional matrix adjust. Identities = 16/47 (34%), Positives = 28/47 (59%), Gaps = 1/47 (2%) Query: 67 HGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREE 113 HG++E K KD+ +K + LRE K + +G+ + + A +K A E+ Sbjct: 387 HGLIEEFKPIKDLNIKKEV-LREGKVKIDKGRTVIDGLAQSKVAAEK 432 >4QS9-A nrPDB Length = 474 Score = 28.5 bits (62), Expect = 3.6, Method: Compositional matrix adjust. Identities = 14/44 (31%), Positives = 24/44 (54%) Query: 159 SNCLETSLAEIFPLGKNHSSKVNSDSGIPGLAASVLVVSHGAYM 202 S C+E+SL E+ + S +V + G+ A++L SH Y+ Sbjct: 428 SECMESSLKELLGDEASGSVEVTHSNDGSGIGAALLAASHSLYL 471 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3DCY-A nrPDB 354 2e-98 3E9D-A nrPDB 275 1e-74 4ODI-A nrPDB 270 3e-73 3KKK-A nrPDB 270 6e-73 5VVE-A nrPDB 258 2e-69 5PGM-D nrPDB 258 2e-69 3GW8-A nrPDB 254 2e-68 4EMB-A nrPDB 250 3e-67 3NFY-A nrPDB 249 1e-66 5Y64-B nrPDB 245 1e-65 3PGM-A nrPDB 245 1e-65 1E58-A nrPDB 243 4e-65 3D8H-A nrPDB 233 4e-62 4EO9-A nrPDB 229 9e-61 5UM0-A nrPDB 222 2e-58 1FZT-A nrPDB 170 5e-43 3LG2-A nrPDB 132 1e-31 4PZA-A nrPDB 128 2e-30 3R7A-A nrPDB 124 4e-29 Sequences not found previously or not previously below threshold: 1RII-A nrPDB 228 2e-60 6NRU-A nrPDB 82 3e-16 4IJ6-A nrPDB 78 3e-15 5HTK-A nrPDB 63 1e-10 5HR5-A nrPDB 63 2e-10 1K6M-A nrPDB 59 1e-09 1C7Z-A nrPDB 59 2e-09 2BIF-A nrPDB 57 8e-09 4D4L-A nrPDB 56 1e-08 2DWP-A nrPDB 56 2e-08 2YN2-A nrPDB 53 2e-07 3HJG-A nrPDB 46 2e-05 3F2I-A nrPDB 41 8e-04 6CIM-N nrPDB 37 0.010 6CG0-N nrPDB 36 0.012 2QBO-A nrPDB 34 0.048 3IDV-A nrPDB 32 0.31 1GR0-A nrPDB 31 0.40 4N5C-A nrPDB 31 0.49 3CF4-A nrPDB 31 0.83 1UJC-A nrPDB 30 0.87 4MDC-A nrPDB 29 1.5 3K9D-A nrPDB 29 2.0 2WOO-A nrPDB 28 3.3 4F61-I nrPDB 28 4.1 >3DCY-A nrPDB Length = 275 Score = 354 bits (908), Expect = 2e-98, Method: Composition-based stats. Identities = 269/269 (100%), Positives = 269/269 (100%) Query: 2 ARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNVKFTHAFSSDLMR 61 ARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNVKFTHAFSSDLMR Sbjct: 7 ARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNVKFTHAFSSDLMR 66 Query: 62 TKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVFTPPG 121 TKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVFTPPG Sbjct: 67 TKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVFTPPG 126 Query: 122 GETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKNHSSKVN 181 GETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKNHSSKVN Sbjct: 127 GETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKNHSSKVN 186 Query: 182 SDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPNTGMSLFIIN 241 SDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPNTGMSLFIIN Sbjct: 187 SDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPNTGMSLFIIN 246 Query: 242 FEEGREVKPTVQCICMNLQDHLNGLTETR 270 FEEGREVKPTVQCICMNLQDHLNGLTETR Sbjct: 247 FEEGREVKPTVQCICMNLQDHLNGLTETR 275 >3E9D-A nrPDB Length = 265 Score = 275 bits (703), Expect = 1e-74, Method: Composition-based stats. Identities = 106/265 (40%), Positives = 152/265 (57%), Gaps = 17/265 (6%) Query: 1 MARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNVKFTHAFSSDLM 60 M FALT+VRHGET++N++K++QGQG+D PLS+TG +QAAAAG +L ++ FT+ F S+L Sbjct: 1 MLTFALTIVRHGETQYNRDKLLQGQGIDTPLSDTGHQQAAAAGRYLKDLHFTNVFVSNLQ 60 Query: 61 RTKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVFTPP 120 R QT IL + + D LRER +GV EG+ L+ MA AA + C +TPP Sbjct: 61 RAIQTAEIILGNNLHSSATEMILDPLLRERGFGVAEGRPKEHLKNMANAAGQSCRDYTPP 120 Query: 121 GGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKNHSSKV 180 GGETL+QVK R F FL L + ++ PS + +A + Sbjct: 121 GGETLEQVKTR---FKMFLKSLFQRMFEEHGSALSSVPSEADQPVIAGL----------- 166 Query: 181 NSDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPNTGMSLFI- 239 +D G + L+VSHGA++R + + DL+C LPA L +++ S PNTG+S FI Sbjct: 167 -ADDGAQNVPVHALMVSHGAFIRISVRHLVEDLQCCLPAGLKMNQVFSPCPNTGISRFIF 225 Query: 240 -INFEEGREVKPTVQCICMNLQDHL 263 I+ EE +Q + +N +DHL Sbjct: 226 TIHREESVLRATRIQGVFINRKDHL 250 >4ODI-A nrPDB Length = 281 Score = 270 bits (691), Expect = 3e-73, Method: Composition-based stats. Identities = 64/265 (24%), Positives = 114/265 (43%), Gaps = 42/265 (15%) Query: 2 ARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNN--VKFTHAFSSDL 59 A++ L ++RHGE+ +NKE G D PLS G ++A A L +F A++S L Sbjct: 17 AKYTLVLIRHGESTWNKENRFTGW-TDVPLSPVGEQEAVEAAKALKEKGFEFDVAYTSVL 75 Query: 60 MRTKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVF-- 117 R T +L+ + C + VK RL ER YG ++G L++ AK E+ ++ Sbjct: 76 QRAVVTCWTVLKGTDMCH-IPVKSSWRLNERHYGALQG--LNKAETAAKHGDEQVKIWRR 132 Query: 118 ----TPPGGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLG 173 PP E D+ + G D + +++ EA + CL+ ++ + P Sbjct: 133 SYDIPPPPLEKSDK-RWPGND---AVYKMVPNEALP--------LTECLKDTVERVLPFW 180 Query: 174 KNHSSKVNSDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPNT 233 +H + + VLV +HG +R L + +S ++ + T Sbjct: 181 FDHIAPSIME------GKRVLVAAHGNSLRGLVKHL---------DKMSDEAVLELNIPT 225 Query: 234 GMSLFIINFEEGREVKPTVQCICMN 258 G+ L +E +++P ++ Sbjct: 226 GVPLV---YELDEDLQPVRHYYLLD 247 >3KKK-A nrPDB Length = 258 Score = 270 bits (689), Expect = 6e-73, Method: Composition-based stats. Identities = 62/268 (23%), Positives = 113/268 (42%), Gaps = 40/268 (14%) Query: 1 MARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFL--NNVKFTHAFSSD 58 M + L ++RHGE+ +NKE G D PLSE G ++A AAG +L N KF ++S Sbjct: 9 MTTYTLVLLRHGESTWNKENKFTGW-TDVPLSEKGEEEAIAAGKYLKEKNFKFDVVYTSV 67 Query: 59 LMRTKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVF- 117 L R T +L+ + + V RL ER G ++G L++ K E+ ++ Sbjct: 68 LKRAICTAWNVLKTADLLH-VPVVKTWRLNERHCGSLQG--LNKSETAKKYGEEQVKIWR 124 Query: 118 ----TPPGGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLG 173 PP + + G + + + K+A + CL+ ++ + P Sbjct: 125 RSYDIPPPKLDKEDNRWPG---HNVVYKNVPKDALP--------FTECLKDTVERVLPFW 173 Query: 174 KNHSSKVNSDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPNT 233 +H + + V+V +HG +R L + LS ++++ + T Sbjct: 174 FDHIAPDILAN------KKVMVAAHGNSLRGLVKHL---------DNLSEADVLELNIPT 218 Query: 234 GMSLFIINFEEGREVKPTVQCICMNLQD 261 G+ L +E +KP ++ ++ Sbjct: 219 GVPLV---YELDENLKPIKHYYLLDSEE 243 >5VVE-A nrPDB Length = 258 Score = 258 bits (659), Expect = 2e-69, Method: Composition-based stats. Identities = 64/266 (24%), Positives = 111/266 (41%), Gaps = 43/266 (16%) Query: 4 FALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFL--NNVKFTHAFSSDLMR 61 + L ++RHGE+ +NKE G D LSETG K+A AG L +F ++S L R Sbjct: 11 YKLVLIRHGESEWNKENKFTGW-YDCGLSETGLKEAKEAGEILLKEGYEFDLCYTSFLKR 69 Query: 62 TKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVF---- 117 +T+ LE VK+ RL ER YG ++G L++ + K E+ ++ Sbjct: 70 AIKTLWIALETMDAMYLPVVKH-WRLNERHYGALQG--LNKTQTAEKHGEEQVKIWRRSY 126 Query: 118 --TPPGGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKN 175 PP E D+ ++ L Q L + + L+ ++ + P + Sbjct: 127 DIPPPALEVTDERYPGHERKYQGLTQEELPK------------TESLKLTVDRVLPYWND 174 Query: 176 HSSKVNSDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPNTGM 235 + + VL+ +HG +R+L Y +S E++ + TG+ Sbjct: 175 VIAPSVKE------GKRVLIAAHGNSLRALVKYL---------DNISEEEIVELNIPTGV 219 Query: 236 SLFIINFEEGREVKPTVQCICMNLQD 261 L +E +KP ++ + Q+ Sbjct: 220 PLV---YELDENLKP-IKHYYLGDQE 241 >5PGM-D nrPDB Length = 246 Score = 258 bits (658), Expect = 2e-69, Method: Composition-based stats. Identities = 57/262 (21%), Positives = 108/262 (41%), Gaps = 42/262 (16%) Query: 5 ALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNVK--FTHAFSSDLMRT 62 L +VRHG++ +N++ + G VD LS G ++AA AG L K ++S L R Sbjct: 2 KLVLVRHGQSEWNEKNLFTGW-VDVKLSAKGQQEAARAGELLKEKKVYPDVLYTSKLSRA 60 Query: 63 KQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVF----- 117 QT + LE++ + V RL ER YG ++GK + + K E+ + Sbjct: 61 IQTANIALEKADRLW-IPVNRSWRLNERHYGDLQGK--DKAETLKKFGEEKFNTYRRSFD 117 Query: 118 -TPPGGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKNH 176 PP + +G + ++++ +L E + L + + P ++ Sbjct: 118 VPPPPIDASSPFSQKGDERYKYVDPNVLPE------------TESLALVIDRLLPYWQDV 165 Query: 177 SSKVNSDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPNTGMS 236 +K +V++ +HG +R L + +S +++ + TG+ Sbjct: 166 IAKDLLS------GKTVMIAAHGNSLRGLVKHL---------EGISDADIAKLNIPTGIP 210 Query: 237 LFIINFEEGREVKPTVQCICMN 258 L FE +KP+ ++ Sbjct: 211 LV---FELDENLKPSKPSYYLD 229 >3GW8-A nrPDB Length = 257 Score = 254 bits (649), Expect = 2e-68, Method: Composition-based stats. Identities = 61/266 (22%), Positives = 110/266 (41%), Gaps = 43/266 (16%) Query: 4 FALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNN--VKFTHAFSSDLMR 61 + L ++RHGE+ +NKE G VD L+E G ++A AG L F A++S L R Sbjct: 10 YKLVLIRHGESTWNKENRFTGW-VDVDLTEQGNREARQAGQLLKEAGYTFDIAYTSVLKR 68 Query: 62 TKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVF---- 117 +T+ + ++ + V + RL ER YG + G L++ AK E+ V+ Sbjct: 69 AIRTLWHVQDQMDLMY-VPVVHSWRLNERHYGALSG--LNKAETAAKYGDEQVLVWRRSY 125 Query: 118 --TPPGGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKN 175 PP E D+ + + +EQ + CL+ ++A + PL Sbjct: 126 DTPPPALEPGDERAPYADPRYAKV---------PREQLPL---TECLKDTVARVLPLWNE 173 Query: 176 HSSKVNSDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPNTGM 235 + VL+ +HG +R+L Y +S ++++ + G+ Sbjct: 174 SIAPAV------KAGKQVLIAAHGNSLRALIKYL---------DGISDADIVGLNIPNGV 218 Query: 236 SLFIINFEEGREVKPTVQCICMNLQD 261 L +E + P ++ + Q+ Sbjct: 219 PLV---YELDESLTP-IRHYYLGDQE 240 >4EMB-A nrPDB Length = 274 Score = 250 bits (639), Expect = 3e-67, Method: Composition-based stats. Identities = 69/274 (25%), Positives = 121/274 (44%), Gaps = 43/274 (15%) Query: 4 FALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLN--NVKFTHAFSSDLMR 61 + L +VRHGE+ +NKE + G D LS+ G +A AG+ L F AFSS L R Sbjct: 28 YKLVLVRHGESEWNKENLFTGW-TDVKLSDKGIDEAVEAGLLLKQEGYSFDIAFSSLLSR 86 Query: 62 TKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVF---- 117 T++ IL ++VK RL ER YG ++G L++ AK ++ ++ Sbjct: 87 ANDTLNIILRELGQSY-ISVKKTWRLNERHYGALQG--LNKSETAAKYGEDKVLIWRRSY 143 Query: 118 -TPPGGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSP-SNCLETSLAEIFPLGKN 175 PP +LD+ R +K+ K + P + CL+ ++A + P + Sbjct: 144 DVPP--MSLDESDDRH----------PIKDPRYKHIPKRELPSTECLKDTVARVIPYWTD 191 Query: 176 HSSKVNSDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPNTGM 235 +K + V+V +HG +R+L YF LS +++ + TG+ Sbjct: 192 EIAKEVLE------GKKVIVAAHGNSLRALVKYF---------DNLSEEDVLKLNIPTGI 236 Query: 236 SLFIINFEEGREVKPTVQCICMNLQDHLNGLTET 269 L +E +++ P ++ + + + E+ Sbjct: 237 PLV---YELDKDLNP-IKHYYLGDESKIKKAMES 266 >3NFY-A nrPDB Length = 267 Score = 249 bits (634), Expect = 1e-66, Method: Composition-based stats. Identities = 61/257 (23%), Positives = 103/257 (40%), Gaps = 33/257 (12%) Query: 1 MARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLN--NVKFTHAFSSD 58 M+++ L ++RHGE +NKE VD+ L+ G ++A G L N +F F+S Sbjct: 1 MSKYKLIMLRHGEGAWNKENRFCSW-VDQKLNSEGMEEARNCGKQLKALNFEFDLVFTSV 59 Query: 59 LMRTKQTMHGILERSKFCKDMTVKYDSRLRERKYGVV-----EGKALSELRAMAKAAREE 113 L R+ T ILE + V+ RL ER YG + E AL+ + R Sbjct: 60 LNRSIHTAWLILEELGQEW-VPVESSWRLNERHYGALIGLNREQMALNHGEEQVRLWRRS 118 Query: 114 CPVFTPPGGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLG 173 V PP E+ + D +C + L + + S L+ L + P Sbjct: 119 YNVTPPPIEESHPYYQEIYNDRRYKVCDVPLDQLPR---------SESLKDVLERLLPYW 169 Query: 174 KNHSSKVNSDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPNT 233 + ++L+ +HG R+L + +S +++++T T Sbjct: 170 NERIAPEVL------RGKTILISAHGNSSRALLKHL---------EGISDEDIINITLPT 214 Query: 234 GMSLFIINFEEGREVKP 250 G+ + + E R V P Sbjct: 215 GVPILLELDENLRAVGP 231 >5Y64-B nrPDB Length = 262 Score = 245 bits (625), Expect = 1e-65, Method: Composition-based stats. Identities = 55/260 (21%), Positives = 97/260 (37%), Gaps = 30/260 (11%) Query: 1 MARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNN--VKFTHAFSSD 58 MA + L ++RHGE+ +N E G D LS G ++A G L + +F F+S Sbjct: 1 MAAYKLVLIRHGESAWNLENRFSGW-YDADLSPAGHEEAKRGGQALRDAGYEFDICFTSV 59 Query: 59 LMRTKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVFT 118 R +T+ +L+ + V RL ER YG + G L++ AK + ++ Sbjct: 60 QKRAIRTLWTVLDAIDQMW-LPVVRTWRLNERHYGGLTG--LNKAETAAKHGEAQVKIWR 116 Query: 119 PPGGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPS-NCLETSLAEIFPLGKNHS 177 V ++ I K+ + PS L+ ++A P Sbjct: 117 R-----SYDVPPPPMEPDHPFYSNISKDRRYADLTEDQLPSCESLKDTIARALPFWNEEI 171 Query: 178 SKVNSDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPNTGMSL 237 + VL+ +HG +R + + LS +M + TG+ + Sbjct: 172 VPQIKE------GKRVLIAAHGNSLRGIVKHL---------EGLSEEAIMELNLPTGIPI 216 Query: 238 FIINFEEGREVKPTVQCICM 257 +E + +KP + Sbjct: 217 V---YELDKNLKPIKPMQFL 233 >3PGM-A nrPDB Length = 244 Score = 245 bits (625), Expect = 1e-65, Method: Composition-based stats. Identities = 55/262 (20%), Positives = 108/262 (41%), Gaps = 44/262 (16%) Query: 5 ALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNN--VKFTHAFSSDLMRT 62 L +VRHG++ +N++ + G VD LS G ++AA AG L V ++S L R Sbjct: 2 KLVLVRHGQSEWNEKNLFTGW-VDVKLSAKGQQEAARAGELLKEKGVNVLVDYTSKLSRA 60 Query: 63 KQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVF----- 117 QT + LE++ + V RL ER YG ++GK + + + K E+ + Sbjct: 61 IQTANIALEKADRLW-IPVNRSWRLNERHYGDLQGK--DKAQTLKKFGEEKFNTYRRSFD 117 Query: 118 -TPPGGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKNH 176 PP + +G + ++++ +L E + L + + P ++ Sbjct: 118 VPPPPIDASSPFSQKGDERYKYVDPNVLPE------------TESLALVIDRLLPYWQDV 165 Query: 177 SSKVNSDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPNTGMS 236 +K+ + + ++ +HG +R L + +S +++ + G Sbjct: 166 IAKL--------VGKTSMIAAHGNSLRGLVKHL---------EGISDADIAKLNIPPGTI 208 Query: 237 LFIINFEEGREVKPTVQCICMN 258 L FE +KP+ ++ Sbjct: 209 LV---FELDENLKPSKPSYYLD 227 >1E58-A nrPDB Length = 249 Score = 243 bits (621), Expect = 4e-65, Method: Composition-based stats. Identities = 60/267 (22%), Positives = 100/267 (37%), Gaps = 43/267 (16%) Query: 5 ALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNN--VKFTHAFSSDLMRT 62 L +VRHGE+++NKE G D LSE G +A AAG L F A++S L R Sbjct: 4 KLVLVRHGESQWNKENRFTGW-YDVDLSEKGVSEAKAAGKLLKEEGYSFDFAYTSVLKRA 62 Query: 63 KQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVF----- 117 T+ +L+ + V+ +L ER YG ++G L++ K E+ + Sbjct: 63 IHTLWNVLDELDQAW-LPVEKSWKLNERHYGALQG--LNKAETAEKYGDEQVKQWRRGFA 119 Query: 118 -TPPGGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKNH 176 TPP D+ + L + L + L ++ + P Sbjct: 120 VTPPELTKDDERYPGHDPRYAKLSEKELP------------LTESLALTIDRVIPYWNET 167 Query: 177 SSKVNSDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPNTGMS 236 V++ +HG +R+L Y +S E++ + TG+ Sbjct: 168 ILPRMKS------GERVIIAAHGNSLRALVKYL---------DNMSEEEILELNIPTGVP 212 Query: 237 LFIINFEEGREVKPTVQCICMNLQDHL 263 L +E KP + + D + Sbjct: 213 LV---YEFDENFKPLKR-YYLGNADEI 235 >3D8H-A nrPDB Length = 267 Score = 233 bits (595), Expect = 4e-62, Method: Composition-based stats. Identities = 63/268 (23%), Positives = 110/268 (41%), Gaps = 42/268 (15%) Query: 2 ARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFL--NNVKFTHAFSSDL 59 + + LT++RHGE+ +NKE G D LSE G +A AG L KF ++S L Sbjct: 19 STYKLTLIRHGESEWNKENRFTGW-TDVSLSEQGVSEAIEAGRMLLEKGFKFDVVYTSVL 77 Query: 60 MRTKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVF-- 117 R T +L+ + + RL ER YG ++G L++ +K ++ ++ Sbjct: 78 KRAIMTTWTVLKELGNINCPIINH-WRLNERHYGALQG--LNKSETASKFGEDQVKIWRR 134 Query: 118 ----TPPGGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLG 173 PP E D ++ +C L + CL+ ++ + P Sbjct: 135 SFDVPPPVLEKSDPRWPGNELIYKGICPSCLP------------TTECLKDTVERVKPY- 181 Query: 174 KNHSSKVNSDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPNT 233 V + S + G SVLV +HG +R+L Y L ++ +++ V T Sbjct: 182 ---FEDVIAPSIMSG--KSVLVSAHGNSLRALL-YLL--------EGMTPEQILEVNIPT 227 Query: 234 GMSLFIINFEEGREVKPTVQCICMNLQD 261 L + E +K T + ++ ++ Sbjct: 228 ACPLVL---ELDDYLKVTKKYYLISEEE 252 >4EO9-A nrPDB Length = 268 Score = 229 bits (584), Expect = 9e-61, Method: Composition-based stats. Identities = 56/261 (21%), Positives = 101/261 (38%), Gaps = 46/261 (17%) Query: 3 RFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFL--NNVKFTHAFSSDLM 60 L ++RHGE+ +N + G VD L++ G +A +G L +N+ ++S L Sbjct: 27 TATLILLRHGESDWNARNLFTGW-VDVGLTDKGRAEAVRSGELLAEHNLLPDVLYTSLLR 85 Query: 61 RTKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVF--- 117 R T H L+ + + + V+ RL ER YG ++G L + A+ E + Sbjct: 86 RAITTAHLALDTADWLW-IPVRRSWRLNERHYGALQG--LDKAVTKARYGEERFMAWRRS 142 Query: 118 ---TPPGGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSP-SNCLETSLAEIFPLG 173 PP E + +AD + G P + CL + P Sbjct: 143 YDTPPPPIEKGSEFSQ---------------DADPRYTDIGGGPLTECLADVVTRFLPYF 187 Query: 174 KNHSSKVNSDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPNT 233 + +VL+V+HG +R+L + +S E++ + T Sbjct: 188 TDVIVPDL------RTGRTVLIVAHGNSLRALVKHL---------DEMSDDEVVGLNVPT 232 Query: 234 GMSLFIINFEEGREVKPTVQC 254 G+ L ++ +++P V Sbjct: 233 GIPL---RYDLDADLRPVVPG 250 >1RII-A nrPDB Length = 265 Score = 228 bits (581), Expect = 2e-60, Method: Composition-based stats. Identities = 57/259 (22%), Positives = 105/259 (40%), Gaps = 46/259 (17%) Query: 5 ALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFL--NNVKFTHAFSSDLMRT 62 +L ++RHGE+ +N + G VD L++ G +A +G + +++ ++S L R Sbjct: 6 SLVLLRHGESDWNALNLFTGW-VDVGLTDKGQAEAVRSGELIAEHDLLPDVLYTSLLRRA 64 Query: 63 KQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVF----- 117 T H L+ + + V+ RL ER YG ++G L + A+ E+ + Sbjct: 65 ITTAHLALDSADRLW-IPVRRSWRLNERHYGALQG--LDKAETKARYGEEQFMAWRRSYD 121 Query: 118 -TPPGGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSP-SNCLETSLAEIFPLGKN 175 PP E Q +AD + G P + CL +A P + Sbjct: 122 TPPPPIERGSQFSQ---------------DADPRYADIGGGPLTECLADVVARFLPYFTD 166 Query: 176 HSSKVNSDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPNTGM 235 G + +VL+V+HG +R+L + +S E++ + TG+ Sbjct: 167 VI------VGDLRVGKTVLIVAHGNSLRALVKHL---------DQMSDDEIVGLNIPTGI 211 Query: 236 SLFIINFEEGREVKPTVQC 254 L ++ ++P V+ Sbjct: 212 PL---RYDLDSAMRPLVRG 227 >5UM0-A nrPDB Length = 235 Score = 222 bits (564), Expect = 2e-58, Method: Composition-based stats. Identities = 58/260 (22%), Positives = 103/260 (39%), Gaps = 43/260 (16%) Query: 6 LTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNN--VKFTHAFSSDLMRTK 63 L +RHG++ +N + + G D LSE G +AAAAG L +F AF+S L R Sbjct: 11 LVFIRHGQSEWNAKNLFTGWR-DVKLSEQGLAEAAAAGKKLKENGYEFDIAFTSVLTRAI 69 Query: 64 QTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVF------ 117 +T + +LE S +K RL ER YG ++G L + + K E+ ++ Sbjct: 70 KTCNIVLEESDQLFVPQIK-TWRLNERHYGRLQG--LDKKQTAEKYGDEQVRIWRRSYDT 126 Query: 118 TPPGGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKNHS 177 PP + D + L ++ + L+ +L + P ++ Sbjct: 127 LPPLLDKDDAFSAHKDRRYAHLPADVVPD------------GENLKVTLERVLPFWEDQI 174 Query: 178 SKVNSDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPNTGMSL 237 + VLV +HG +R+L + +S ++M + TG L Sbjct: 175 APAILS------GKRVLVAAHGNSLRALAKHI---------EGISDEDIMGLEIPTGQPL 219 Query: 238 FIINFEEGREVKPTVQCICM 257 ++ +K ++ + Sbjct: 220 V---YKLDDNLK-VIEKFYL 235 >1FZT-A nrPDB Length = 211 Score = 170 bits (430), Expect = 5e-43, Method: Composition-based stats. Identities = 58/249 (23%), Positives = 92/249 (36%), Gaps = 64/249 (25%) Query: 6 LTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLN--NVKFTHAFSSDLMRTK 63 L + RHGE+ +NK + G D LSETG K+A G L KF AF+S L R + Sbjct: 10 LVLTRHGESEWNKLNLFTGWK-DPALSETGIKEAKLGGERLKSRGYKFDIAFTSALQRAQ 68 Query: 64 QTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVF------ 117 +T ILE T+K + +L ER YG ++G L++ A K E+ ++ Sbjct: 69 KTCQIILEEVGEPNLETIKSE-KLNERYYGDLQG--LNKDDARKKWGAEQVQIWRRSYDI 125 Query: 118 TPPGGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKNHS 177 PP GE+L + P K+ Sbjct: 126 APPNGESLKDTA-------------------------------------ERVLPYYKSTI 148 Query: 178 SKVNSDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPNTGMSL 237 VL+ +HG +R+L L+ +++ TG+ + Sbjct: 149 VPHILK------GEKVLIAAHGNSLRALIMDL---------EGLTGDQIVKRELATGVPI 193 Query: 238 FIINFEEGR 246 ++G+ Sbjct: 194 VYHLDKDGK 202 >3LG2-A nrPDB Length = 292 Score = 132 bits (332), Expect = 1e-31, Method: Composition-based stats. Identities = 54/212 (25%), Positives = 83/212 (39%), Gaps = 54/212 (25%) Query: 7 TVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGI-------FLNNVKFTHAFSSDL 59 +VRHG+T ++K G D PL+ G Q G FLN T+ F+S Sbjct: 30 IIVRHGQTEWSKSGQYTGL-TDLPLTPYGEGQMLRTGESVFRNNQFLNPDNITYIFTSPR 88 Query: 60 MRTKQTMHGILERS--KFCKDMTVKYDSRLRERKYGVVEG---KALSELRAMAKAAREEC 114 +R +QT+ +L+ + + V D LRE +YG EG + + ELR +E Sbjct: 89 LRARQTVDLVLKPLSDEQRAKIRVVVDDDLREWEYGDYEGMLTREIIELRKSRGLDKERP 148 Query: 115 PVFTPPG---GETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFP 171 G GET Q+ +R L ++A I Sbjct: 149 WNIWRDGCENGETTQQIGLR------------------------------LSRAIARIQN 178 Query: 172 LGKNHSSKVNSDSGIPGLAASVLVVSHGAYMR 203 L + H S+ G A+ ++V +HG +R Sbjct: 179 LHRKHQSE--------GRASDIMVFAHGHALR 202 >4PZA-A nrPDB Length = 223 Score = 128 bits (321), Expect = 2e-30, Method: Composition-based stats. Identities = 50/161 (31%), Positives = 72/161 (44%), Gaps = 11/161 (6%) Query: 1 MARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNVKFTHAFSSDLM 60 M L ++RHG+T +N +QGQ +D LSE G QA AA L + SSDL Sbjct: 1 MRARRLVMLRHGQTDYNVGSRMQGQ-LDTELSELGRTQAVAAAEVLGKRQPLLIVSSDLR 59 Query: 61 RTKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAR---EECPVF 117 R T + ER+ + V+ D+RLRE G +G +++ A A AR E + Sbjct: 60 RAYDTAVKLGERTG----LVVRVDTRLRETHLGDWQGLTHAQIDADAPGARLAWREDATW 115 Query: 118 TPPGGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSP 158 P GGE+ V R + +L+ E + P Sbjct: 116 APHGGESRVDVAARS---RPLVAELVASEPEWGGADEPDRP 153 >3R7A-A nrPDB Length = 237 Score = 124 bits (311), Expect = 4e-29, Method: Composition-based stats. Identities = 56/224 (25%), Positives = 90/224 (40%), Gaps = 28/224 (12%) Query: 5 ALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNVKFTHAFSSDLMRTKQ 64 L V RHG+T N QG D PL E G + A G L ++ F +A+SSD R + Sbjct: 15 TLYVTRHGKTILNTNHRAQGWA-DSPLVEKGVEVATNLGTGLKDIHFMNAYSSDSGRAIE 73 Query: 65 TMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELR-AMAKAAREECPVFTPPGGE 123 T + +L+ S+ K + ++ +LRE +G+ EG+ L + A+ KAA E Sbjct: 74 TANLVLKYSEQSK-LKLEQRKKLRELNFGIFEGEKLDNMWDAVGKAAGVTS------PEE 126 Query: 124 TLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKNHSSKVNSD 183 L ID K+A+ E FS + + S+ Sbjct: 127 LLKFSIQEVIDLIRAADPT--KQAEDWELFSTRIKAEIDK-----------------ISE 167 Query: 184 SGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELM 227 +VLVV HG + +L + + S ++++ Sbjct: 168 EAAKDGGGNVLVVVHGLLITTLIEMLDSSKTKLGVENASVTKIV 211 >6NRU-A nrPDB Length = 206 Score = 81.8 bits (200), Expect = 3e-16, Method: Composition-based stats. Identities = 38/170 (22%), Positives = 62/170 (36%), Gaps = 14/170 (8%) Query: 5 ALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNVKFTHAFSSDLMRTKQ 64 L ++RHGET+ N + + G PL+ G +QA L++V F S+L R + Sbjct: 5 RLWLIRHGETQANVDGLYSGHAP-TPLTARGIEQAQNLHTLLDDVSFDLVLCSELERAQH 63 Query: 65 TMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSE-LRAMAKAAREECPVF---TPP 120 T +L + + V L E +G E + + ++ A+ C + P Sbjct: 64 TARLVLSD----RQLPVHIIPELNEMFFGDWEMRHHRDLMQEDAENYSAWCNDWQHAIPT 119 Query: 121 GGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIF 170 GE R F L E + S L +A + Sbjct: 120 NGEGFQAFSQRVERFIARL-----SEYQHYQNILIVSHQGVLSLLIARLI 164 >4IJ6-A nrPDB Length = 211 Score = 78.4 bits (191), Expect = 3e-15, Method: Composition-based stats. Identities = 43/143 (30%), Positives = 61/143 (42%), Gaps = 13/143 (9%) Query: 5 ALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNVKFTHAFSSDLMRTKQ 64 L +VR E+ +N QG +D LSE G KQA L+ +SS L RT Sbjct: 3 KLILVRAAESEWNPVGRYQGL-LDPDLSERGKKQAKLLAQELSREHLDVIYSSPLKRTYL 61 Query: 65 TMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAARE-ECPVFTPP--- 120 T I E K++ V + R+ E +G+ G + E+ M K + V P Sbjct: 62 TALEIAE----AKNLEVIKEDRIIEIDHGMWSGMLVEEV--MEKYPEDFRRWVEEPHKVE 115 Query: 121 --GGETLDQVKMRGIDFFEFLCQ 141 GGE+L V R F E + + Sbjct: 116 FQGGESLASVYNRVKGFLEEVRK 138 >5HTK-A nrPDB Length = 505 Score = 63.3 bits (152), Expect = 1e-10, Method: Composition-based stats. Identities = 45/216 (20%), Positives = 69/216 (31%), Gaps = 57/216 (26%) Query: 5 ALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNVKFTH--AFSSDLMRT 62 + + RHGE+ FN I G D LS G + A A FL + T ++S L RT Sbjct: 251 TIYLCRHGESEFNLLGKIGG---DSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRT 307 Query: 63 KQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVFTPPGG 122 QT + + + L E GV E +E+ Sbjct: 308 IQTAESLG--------VPYEQWKILNEIDAGVCEEMTYAEIEKRYP-------------- 345 Query: 123 ETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKNHSSKVNS 182 ++ +R + + + + + + P+ Sbjct: 346 ---EEFALRDQEKYLYRYP----------------GGESYQDLVQRLEPVIMEL------ 380 Query: 183 DSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLP 218 +VLV+SH A MR L YFL LP Sbjct: 381 -----ERQGNVLVISHQAVMRCLLAYFLDKGADELP 411 >5HR5-A nrPDB Length = 531 Score = 62.6 bits (150), Expect = 2e-10, Method: Composition-based stats. Identities = 47/217 (21%), Positives = 72/217 (33%), Gaps = 59/217 (27%) Query: 5 ALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNVKF--THAFSSDLMRT 62 + + RHGE+ FN I G D LS G + A A FL + ++S L RT Sbjct: 252 TIYLCRHGESEFNLLGKIGG---DSGLSVRGKQFAQALRKFLEEQEIADLKVWTSQLKRT 308 Query: 63 KQTMHGILERSKFCKDMTVKYDSR-LRERKYGVVEGKALSELRAMAKAAREECPVFTPPG 121 QT + + + L E GV E +E++ E+ P Sbjct: 309 IQTAESLGVTYEQ---------WKILNEIDAGVCEEMTYAEIQ-------EQYP------ 346 Query: 122 GETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKNHSSKVN 181 D+ +R + + + + + + P+ Sbjct: 347 ----DEFALRDEEKYLYRYP----------------GGESYQDLVQRLEPVIMEL----- 381 Query: 182 SDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLP 218 +VLV+SH A MR L YFL LP Sbjct: 382 ------ERQGNVLVISHQAVMRCLLAYFLDKGADELP 412 >1K6M-A nrPDB Length = 432 Score = 59.5 bits (142), Expect = 1e-09, Method: Composition-based stats. Identities = 43/216 (19%), Positives = 67/216 (31%), Gaps = 57/216 (26%) Query: 5 ALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLN--NVKFTHAFSSDLMRT 62 ++ + RHGE+ N I G D LS G + A A F+ + F+S + RT Sbjct: 214 SIYLCRHGESELNIRGRIGG---DSGLSVRGKQYAYALANFIQSQGISSLKVFTSRMKRT 270 Query: 63 KQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVFTPPGG 122 QT + + + L E GV E E++ Sbjct: 271 IQTAEALG--------VPYEQFKALNEIDAGVCEEMTYEEIQEHYP-------------- 308 Query: 123 ETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKNHSSKVNS 182 ++ +R D + + E + + P+ Sbjct: 309 ---EEFALRDQDKYRYRYP----------------KGESYEDLVQRLEPVIMEL------ 343 Query: 183 DSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLP 218 +VLV+ H A MR L YFL LP Sbjct: 344 -----ERQENVLVICHQAVMRCLLAYFLDKSSEELP 374 >1C7Z-A nrPDB Length = 191 Score = 58.7 bits (140), Expect = 2e-09, Method: Composition-based stats. Identities = 42/216 (19%), Positives = 67/216 (31%), Gaps = 57/216 (26%) Query: 5 ALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLN--NVKFTHAFSSDLMRT 62 ++ + RHGE+ N I G D LS G + A A F+ + ++S + RT Sbjct: 3 SIYLCRHGESELNLRGRIGG---DSGLSARGKQYAYALANFIRSQGISSLKVWTSHMKRT 59 Query: 63 KQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVFTPPGG 122 QT + + + L E GV E E++ Sbjct: 60 IQTAEALG--------VPYEQWKALNEIDAGVCEEMTYEEIQEHYP-------------- 97 Query: 123 ETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKNHSSKVNS 182 ++ +R D + + E + + P+ Sbjct: 98 ---EEFALRDQDKYRYRYP----------------KGESYEDLVQRLEPVIMEL------ 132 Query: 183 DSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLP 218 +VLV+ H A MR L YFL LP Sbjct: 133 -----ERQENVLVICHQAVMRCLLAYFLDKSSDELP 163 >2BIF-A nrPDB Length = 469 Score = 57.2 bits (136), Expect = 8e-09, Method: Composition-based stats. Identities = 40/216 (18%), Positives = 66/216 (30%), Gaps = 57/216 (26%) Query: 5 ALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNVKF--THAFSSDLMRT 62 ++ + R GE+ N + I G D LS G + + F+++ F+S + RT Sbjct: 251 SIYLCRAGESELNLKGRIGG---DPGLSPRGREFSKHLAQFISDQNIKDLKVFTSQMKRT 307 Query: 63 KQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVFTPPGG 122 QT + + + L E GV E E++ Sbjct: 308 IQTAEAL--------SVPYEQFKVLNEIDAGVCEEMTYEEIQDHYPL------------- 346 Query: 123 ETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKNHSSKVNS 182 + +R D + + E + + P+ Sbjct: 347 ----EFALRDQDKYRYRYP----------------KGESYEDLVQRLEPVIMEL------ 380 Query: 183 DSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLP 218 +VLV+ H A MR L YFL LP Sbjct: 381 -----ERQENVLVICHQAVMRCLLAYFLDKAAEELP 411 >4D4L-A nrPDB Length = 449 Score = 56.4 bits (134), Expect = 1e-08, Method: Composition-based stats. Identities = 43/216 (19%), Positives = 69/216 (31%), Gaps = 57/216 (26%) Query: 5 ALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLN--NVKFTHAFSSDLMRT 62 + + RHGE N + I G D LS G K A+A F+ N+K ++S L T Sbjct: 248 TIYLCRHGENEHNLQGRIGG---DSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQLKST 304 Query: 63 KQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVFTPPGG 122 QT + + + L E GV E E+R + Sbjct: 305 IQTAEAL--------RLPYEQWKALNEIDAGVCEELTYEEIRD----------TYP---- 342 Query: 123 ETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKNHSSKVNS 182 ++ +R D + + + + + P+ Sbjct: 343 ---EEYALREQDKYYYRYPT----------------GESYQDLVQRLEPVIMEL------ 377 Query: 183 DSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLP 218 +VLV+ H A +R L YFL +P Sbjct: 378 -----ERQENVLVICHQAVLRCLLAYFLDKSAEEMP 408 >2DWP-A nrPDB Length = 520 Score = 56.0 bits (133), Expect = 2e-08, Method: Composition-based stats. Identities = 43/216 (19%), Positives = 68/216 (31%), Gaps = 57/216 (26%) Query: 5 ALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLN--NVKFTHAFSSDLMRT 62 + + RHGE N + I G D LS G K A+A F+ N+K ++S L T Sbjct: 248 TIYLCRHGENEHNLQGRIGG---DSGLSSRGKKFASALSKFVEEQNLKDLRVWTSQLKST 304 Query: 63 KQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVFTPPGG 122 QT + + + L E GV E E+R Sbjct: 305 IQTAEAL--------RLPYEQWKALNEIDAGVCEELTYEEIRDTYP-------------- 342 Query: 123 ETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKNHSSKVNS 182 ++ +R D + + + + + P+ Sbjct: 343 ---EEYALREQDKYYYRYPT----------------GESYQDLVQRLEPVIMEL------ 377 Query: 183 DSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLP 218 +VLV+ H A +R L YFL +P Sbjct: 378 -----ERQENVLVICHQAVLRCLLAYFLDKSAEEMP 408 >2YN2-A nrPDB Length = 279 Score = 52.6 bits (124), Expect = 2e-07, Method: Composition-based stats. Identities = 39/225 (17%), Positives = 70/225 (31%), Gaps = 44/225 (19%) Query: 1 MARFALTVVRHG-ETRF----NKEKIIQGQGVDEPLSETGFKQAAAAGIFLN--NVKFTH 53 MA + + RHG + + G D PLSE G +QA +++ +VK Sbjct: 10 MAIENIYIARHGYRSNWLPKGPYPPPPTGIDNDVPLSEHGVEQAHELANYISKLDVKPEM 69 Query: 54 AFSSDLMRTKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREE 113 FSS R +T +E K + + D + E + + Sbjct: 70 IFSSPFYRCLETSKPTVEALK----IPLYVDRGVGEWY-------------------KPD 106 Query: 114 CPVFTPPGGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLG 173 P+ P +F +I + + S + E Sbjct: 107 RPIIPEPAT---------HEVMSKFFPSMISPDWEPSIIPSNKGETE--EDIFERCHKFW 155 Query: 174 KNHSSKVNSDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLP 218 +V + P + ++++V+H A +L L P Sbjct: 156 PVFIDRV--ERKFPNV-KTIMIVTHAATKSALGMNLLKFSSAKEP 197 >3HJG-A nrPDB Length = 213 Score = 46.0 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 30/210 (14%), Positives = 62/210 (29%), Gaps = 51/210 (24%) Query: 1 MARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNVKFTHAFSSDLM 60 + + ++RHG+ + GQ D + E +Q A SS L Sbjct: 3 LKTLNIYLMRHGKVD--AAPGLHGQ-TDLKVKEA-EQQQIAMAWKTKGYDVAGIISSPLS 58 Query: 61 RTKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVFTPP 120 R + E+ + + + + L+E +G +G L ++ + P Sbjct: 59 RCHDLAQILAEQ----QLLPMTTEDDLQEMDFGDFDGMPFDLLTE---HWKKLDAFWQSP 111 Query: 121 GGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKNHSSKV 180 +L + L T + + + Sbjct: 112 AHHSLPN-------------------------------AESLSTFSQRVSRAWSQIINDI 140 Query: 181 NSDSGIPGLAASVLVVSHGAYMRSLFDYFL 210 N ++L+V+HG +R + + L Sbjct: 141 ND---------NLLIVTHGGVIRIILAHVL 161 >3F2I-A nrPDB Length = 172 Score = 40.6 bits (93), Expect = 8e-04, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 32/81 (39%), Gaps = 7/81 (8%) Query: 6 LTVVRHGETRFNKEKIIQGQGVDE-PLSETGFKQAAAAGIFLN--NVKFTHAFSSDLMRT 62 L ++RHG K G +E L++ G ++ L +F +S L+R Sbjct: 3 LYLIRHGIAEAQK----TGIKDEERELTQEGKQKTEKVAYRLVKLGRQFDLIVTSPLIRA 58 Query: 63 KQTMHGILERSKFCKDMTVKY 83 +QT +L C+ + Sbjct: 59 RQTAEILLASGLSCQLEESNH 79 >6CIM-N nrPDB Length = 163 Score = 36.8 bits (83), Expect = 0.010, Method: Composition-based stats. Identities = 17/106 (16%), Positives = 35/106 (33%), Gaps = 6/106 (5%) Query: 82 KYDSRLRERKYGVVEGKALSELRAMAKAA----REECPVFTPPGGETLDQVKMRGIDFFE 137 ++ + ER + + K + MAKA E + PP GET + K Sbjct: 40 EFSKKCSER-WKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRP 98 Query: 138 FLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKNHSSKVNSD 183 L ++ + + P + ++ + N ++ Sbjct: 99 P-SAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQP 143 >6CG0-N nrPDB Length = 126 Score = 36.4 bits (82), Expect = 0.012, Method: Composition-based stats. Identities = 17/102 (16%), Positives = 35/102 (34%), Gaps = 6/102 (5%) Query: 82 KYDSRLRERKYGVVEGKALSELRAMAKAA----REECPVFTPPGGETLDQVKMRGIDFFE 137 ++ + ER + + K + MAKA E + PP GET + K Sbjct: 26 EFSKKCSER-WKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRP 84 Query: 138 FLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKNHSSK 179 L ++ + + P + ++ + N ++ Sbjct: 85 P-SAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAAD 125 >2QBO-A nrPDB Length = 421 Score = 34.4 bits (77), Expect = 0.048, Method: Composition-based stats. Identities = 18/125 (14%), Positives = 35/125 (28%), Gaps = 13/125 (10%) Query: 49 VKFTHAFSSDLMRTKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAK 108 F S+L Q +L+ S + +R + G+ + E + Sbjct: 25 FDFDMYNPSNLSAGVQEAWAVLQESN----VPDLVWTRCNGGHWIATRGQLIREAYEDYR 80 Query: 109 AAREECPVFTPPGGETLDQVKMRGIDFFEF---------LCQLILKEADQKEQFSQGSPS 159 ECP GE D + + + ++ + + + Q S Sbjct: 81 HFSSECPFIPREAGEAYDFIPTSMDPPEQRQFRALANQVVGMPVVDKLENRIQELACSLI 140 Query: 160 NCLET 164 L Sbjct: 141 ESLRP 145 >3IDV-A nrPDB Length = 241 Score = 31.8 bits (70), Expect = 0.31, Method: Composition-based stats. Identities = 21/108 (19%), Positives = 39/108 (36%), Gaps = 12/108 (11%) Query: 94 VVEGKALSELRAMAKAAREECPVFTPPGG-----------ETLDQVKMRGIDFFEFLCQL 142 EG ++ +AK P +TPP E ++ + ++F+ C Sbjct: 103 DYEGSR-TQEEIVAKVREVSQPDWTPPPEVTLVLTKENFDEVVNDADIILVEFYAPWCGH 161 Query: 143 ILKEADQKEQFSQGSPSNCLETSLAEIFPLGKNHSSKVNSDSGIPGLA 190 K A + E+ ++ LA++ + +K SG P L Sbjct: 162 CKKLAPEYEKAAKELSKRSPPIPLAKVDATAETDLAKRFDVSGYPTLK 209 >1GR0-A nrPDB Length = 367 Score = 31.4 bits (69), Expect = 0.40, Method: Composition-based stats. Identities = 21/122 (17%), Positives = 41/122 (33%), Gaps = 11/122 (9%) Query: 47 NNVKFTHAFSSDLMRTKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAM 106 + T A +S+L R +T + S + R+ Y +EG+A ++ Sbjct: 248 KKISKTQAVTSNLKREFKTKDVHIGPSDHVGWL------DDRKWAYVRLEGRAFGDVPLN 301 Query: 107 AKAAREECPVFTPPGGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSL 166 + + E G +D V+ I + ++ + SP L + Sbjct: 302 LEY-KLEVWDSPNSAGVIIDAVRAAKIAKDRGIGGPVI----PASAYLMKSPPEQLPDDI 356 Query: 167 AE 168 A Sbjct: 357 AR 358 >4N5C-A nrPDB Length = 802 Score = 31.4 bits (69), Expect = 0.49, Method: Composition-based stats. Identities = 8/44 (18%), Positives = 16/44 (36%) Query: 44 IFLNNVKFTHAFSSDLMRTKQTMHGILERSKFCKDMTVKYDSRL 87 L ++F ++++ R +T LE K+ L Sbjct: 483 KALRELQFKYSYTLAQQRHIETAIKTLESLILSKNPNYYKAWHL 526 >3CF4-A nrPDB Length = 807 Score = 30.6 bits (67), Expect = 0.83, Method: Composition-based stats. Identities = 13/43 (30%), Positives = 22/43 (51%), Gaps = 5/43 (11%) Query: 196 VSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVT--PNTGMS 236 +HG R L D+ + LP TL +S +++ +TG+S Sbjct: 118 AAHG---RHLLDHLIEKYGEDLPLTLGQSNVLTPNITISTGLS 157 >1UJC-A nrPDB Length = 161 Score = 30.2 bits (66), Expect = 0.87, Method: Composition-based stats. Identities = 14/78 (17%), Positives = 27/78 (34%), Gaps = 11/78 (14%) Query: 8 VVRHGETRFNKEKIIQGQGVDE--PLSETGFKQAAAAGIFLNNVKFTH--AFSSDLMRTK 63 ++RHG+ + D PL+ G ++ +L K S +R + Sbjct: 5 IMRHGDAALDA-------ASDSVRPLTTNGCDESRLMANWLKGQKVEIERVLVSPFLRAE 57 Query: 64 QTMHGILERSKFCKDMTV 81 QT+ + + V Sbjct: 58 QTLEEVGDCLNLPSSAEV 75 >4MDC-A nrPDB Length = 252 Score = 29.4 bits (64), Expect = 1.5, Method: Composition-based stats. Identities = 15/63 (23%), Positives = 20/63 (31%), Gaps = 1/63 (1%) Query: 25 QGVDEPLSETGFKQAAAAGIFLNNVKFTHAFSSDLMRTKQTMHGILERSKFCKDMTVKYD 84 G LSE + + LN + D MR I E + +K D Sbjct: 45 YGYQTELSEEQPWENRRDFLTLNPAGTLPVYVDDSMRALCGATIISEYLDETSGI-MKRD 103 Query: 85 SRL 87 RL Sbjct: 104 RRL 106 >3K9D-A nrPDB Length = 464 Score = 29.1 bits (63), Expect = 2.0, Method: Composition-based stats. Identities = 8/69 (11%), Positives = 24/69 (34%) Query: 165 SLAEIFPLGKNHSSKVNSDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRS 224 +A + P S+ + S++ H ++++ + + + A + Sbjct: 111 VVAGLIPSTNPTSTVIYKTLISIKAGNSIVFSPHPNALKAILETVRIISEAAEKAGCPKG 170 Query: 225 ELMSVTPNT 233 + +T T Sbjct: 171 AISCMTVPT 179 >2WOO-A nrPDB Length = 329 Score = 28.3 bits (61), Expect = 3.3, Method: Composition-based stats. Identities = 23/151 (15%), Positives = 44/151 (29%), Gaps = 15/151 (9%) Query: 17 NKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNVK--------FTHAFSSDLMRTKQTMHG 68 N + G D + G +A A L +K F A + +R Sbjct: 104 NPNNPLSGMMQDLAFTIPGIDEALAFAEILKQIKSMEFDCVIFDTAPTGHTLRFLNFPTV 163 Query: 69 ILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVFTPPGGETLDQV 128 + + ++ ++ + + G + G +E K + E Q Sbjct: 164 LEKALGKLGGLSSRFGPMINQ--MGSIMGVNANEQDLFGKMESMRANI-----SEVNKQF 216 Query: 129 KMRGIDFFEFLCQLILKEADQKEQFSQGSPS 159 K + F +C + E+ Q S Sbjct: 217 KNPDLTTFVCVCISEFLSLYETERMIQELTS 247 >4F61-I nrPDB Length = 240 Score = 28.3 bits (61), Expect = 4.1, Method: Composition-based stats. Identities = 15/110 (13%), Positives = 38/110 (34%), Gaps = 5/110 (4%) Query: 58 DLMRTKQTMHGILERSKFCKDMTVKYDSRLRERKYGV----VEGKALSELRAMAKAAREE 113 + R + + ++ +K ++ + RE + ++ K + + A EE Sbjct: 79 VIQRAIEENNNWIKMAKEKLAQKMESNKENREAHFAAMLERLQEKDK-HAEEVRQRAIEE 137 Query: 114 CPVFTPPGGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLE 163 + E L Q + ++ +LK +K + + +E Sbjct: 138 NNNWIKMAKEKLAQKMESNKENRKYQEAELLKHLAEKREHEREVIQRAIE 187 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.118 0.315 Lambda K H 0.267 0.0364 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 8,779,050 Number of Sequences: 36641 Number of extensions: 306131 Number of successful extensions: 944 Number of sequences better than 10.0: 44 Number of HSP's better than 10.0 without gapping: 38 Number of HSP's successfully gapped in prelim test: 38 Number of HSP's that attempted gapping in prelim test: 749 Number of HSP's gapped (non-prelim): 87 length of query: 270 length of database: 10,336,785 effective HSP length: 95 effective length of query: 175 effective length of database: 6,855,890 effective search space: 1199780750 effective search space used: 1199780750 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 58 (27.1 bits)