BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9MAA7 (345 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2ZSH-A nrPDB 706 0.0 3EBL-A nrPDB 448 e-126 2O7R-A nrPDB 120 1e-27 4WY8-A nrPDB 105 2e-23 3AIM-A nrPDB 105 4e-23 4V2I-A nrPDB 103 9e-23 2YH2-A nrPDB 97 8e-21 2C7B-A nrPDB 91 9e-19 4WY5-A nrPDB 83 2e-16 6AAE-A nrPDB 80 1e-15 5L2P-A nrPDB 77 2e-14 3WJ2-A nrPDB 75 5e-14 4KRY-A nrPDB 54 1e-07 3GA7-A nrPDB 51 8e-07 1C7J-A nrPDB 39 0.002 1THG-A nrPDB 35 0.045 5THM-A nrPDB 35 0.046 5YDJ-A nrPDB 35 0.062 2X8B-A nrPDB 34 0.096 5YDI-A nrPDB 34 0.098 1Q83-A nrPDB 34 0.099 6QAA-A nrPDB 33 0.16 3BIX-A nrPDB 33 0.26 4QWW-A nrPDB 32 0.30 4XHP-A nrPDB 32 0.53 4XHO-A nrPDB 32 0.53 5V5V-A nrPDB 31 0.81 1IKQ-A nrPDB 30 1.7 2WQZ-A nrPDB 29 2.6 4YE5-A nrPDB 29 3.0 1QON-A nrPDB 28 5.6 4A39-A nrPDB 28 6.4 >2ZSH-A nrPDB Length = 351 Score = 706 bits (1823), Expect = 0.0, Method: Compositional matrix adjust. Identities = 344/344 (100%), Positives = 344/344 (100%) Query: 1 MAASDEVNLIESRTVVPLNTWVLISNFKVAYNILRRPDGTFNRHLAEYLDRKVTANANPV 60 MAASDEVNLIESRTVVPLNTWVLISNFKVAYNILRRPDGTFNRHLAEYLDRKVTANANPV Sbjct: 8 MAASDEVNLIESRTVVPLNTWVLISNFKVAYNILRRPDGTFNRHLAEYLDRKVTANANPV 67 Query: 61 DGVFSFDVLIDRRINLLSRVYRPAYADQEQPPSILDLEKPVDGDIVPVILFFHGGSFAHS 120 DGVFSFDVLIDRRINLLSRVYRPAYADQEQPPSILDLEKPVDGDIVPVILFFHGGSFAHS Sbjct: 68 DGVFSFDVLIDRRINLLSRVYRPAYADQEQPPSILDLEKPVDGDIVPVILFFHGGSFAHS 127 Query: 121 SANSAIYDTLCRRLVGLCKCVVVSVNYRRAPENPYPCAYDDGWIALNWVNSRSWLKSKKD 180 SANSAIYDTLCRRLVGLCKCVVVSVNYRRAPENPYPCAYDDGWIALNWVNSRSWLKSKKD Sbjct: 128 SANSAIYDTLCRRLVGLCKCVVVSVNYRRAPENPYPCAYDDGWIALNWVNSRSWLKSKKD 187 Query: 181 SKVHIFLAGDSSGGNIAHNVALRAGESGIDVLGNILLNPMFGGNERTESEKSLDGKYFVT 240 SKVHIFLAGDSSGGNIAHNVALRAGESGIDVLGNILLNPMFGGNERTESEKSLDGKYFVT Sbjct: 188 SKVHIFLAGDSSGGNIAHNVALRAGESGIDVLGNILLNPMFGGNERTESEKSLDGKYFVT 247 Query: 241 VRDRDWYWKAFLPEGEDREHPACNPFSPRGKSLEGVSFPKSLVVVAGLDLIRDWQLAYAE 300 VRDRDWYWKAFLPEGEDREHPACNPFSPRGKSLEGVSFPKSLVVVAGLDLIRDWQLAYAE Sbjct: 248 VRDRDWYWKAFLPEGEDREHPACNPFSPRGKSLEGVSFPKSLVVVAGLDLIRDWQLAYAE 307 Query: 301 GLKKAGQEVKLMHLEKATVGFYLLPNNNHFHNVMDEISAFVNAE 344 GLKKAGQEVKLMHLEKATVGFYLLPNNNHFHNVMDEISAFVNAE Sbjct: 308 GLKKAGQEVKLMHLEKATVGFYLLPNNNHFHNVMDEISAFVNAE 351 >3EBL-A nrPDB Length = 365 Score = 448 bits (1152), Expect = e-126, Method: Compositional matrix adjust. Identities = 216/350 (61%), Positives = 267/350 (76%), Gaps = 9/350 (2%) Query: 2 AASDEVNLIESRTVVPLNTWVLISNFKVAYNILRRPDGTFNRHLAEYLDRKVTANANPVD 61 A SDEVN E +TVVPL+TWVLISNFK++YNILRR DGTF R L EYLDR+V ANA P++ Sbjct: 1 AGSDEVNRNECKTVVPLHTWVLISNFKLSYNILRRADGTFERDLGEYLDRRVPANARPLE 60 Query: 62 GVFSFDVLIDRRINLLSRVYRPAYADQEQPPSILDLEKPV--------DGDIVPVILFFH 113 GV SFD +ID+ + L R+YR A A+ + + +P+ + PVI+FFH Sbjct: 61 GVSSFDHIIDQSVGLEVRIYRAA-AEGDAEEGAAAVTRPILEFLTDAPAAEPFPVIIFFH 119 Query: 114 GGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRAPENPYPCAYDDGWIALNWVNSRS 173 GGSF HSSA+S IYD+LCRR V L K VVVSVNYRRAPE+ YPCAYDDGW AL WV S+ Sbjct: 120 GGSFVHSSASSTIYDSLCRRFVKLSKGVVVSVNYRRAPEHRYPCAYDDGWTALKWVMSQP 179 Query: 174 WLKSKKDSKVHIFLAGDSSGGNIAHNVALRAGESGIDVLGNILLNPMFGGNERTESEKSL 233 +++S D++ +FL+GDSSGGNIAH+VA+RA + G+ V GNILLN MFGG ERTESE+ L Sbjct: 180 FMRSGGDAQARVFLSGDSSGGNIAHHVAVRAADEGVKVCGNILLNAMFGGTERTESERRL 239 Query: 234 DGKYFVTVRDRDWYWKAFLPEGEDREHPACNPFSPRGKSLEGVSFPKSLVVVAGLDLIRD 293 DGKYFVT++DRDWYWKA+LPE DR+HPACNPF P G+ L G+ F KSL++V+GLDL D Sbjct: 240 DGKYFVTLQDRDWYWKAYLPEDADRDHPACNPFGPNGRRLGGLPFAKSLIIVSGLDLTCD 299 Query: 294 WQLAYAEGLKKAGQEVKLMHLEKATVGFYLLPNNNHFHNVMDEISAFVNA 343 QLAYA+ L++ G VK++ E ATVGFYLLPN H+H VM+EIS F+NA Sbjct: 300 RQLAYADALREDGHHVKVVQCENATVGFYLLPNTVHYHEVMEEISDFLNA 349 >2O7R-A nrPDB Length = 338 Score = 120 bits (300), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 81/216 (37%), Positives = 116/216 (53%), Gaps = 14/216 (6%) Query: 106 VPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRAPENPYPCAYDDGWIA 165 +P++++FHGG F SA S I+ C + V+ SV+YR APE+ P AYDD A Sbjct: 83 LPLVVYFHGGGFILFSAASTIFHDFCCEMAVHAGVVIASVDYRLAPEHRLPAAYDDAMEA 142 Query: 166 LNWV-NSR-SWLKSKKDSKVHIFLAGDSSGGNIAHNVALRAGESGIDVL-----GNILLN 218 L W+ +SR WL + D + F+ G+S+GGNIA++ LRA ++L G +L Sbjct: 143 LQWIKDSRDEWLTNFADFS-NCFIMGESAGGNIAYHAGLRAAAVADELLPLKIKGLVLDE 201 Query: 219 PMFGGNERTESEKSLDGKYFVTVRDRDWYWKAFLPEGEDREHPACNPFSPRGKSLEGVSF 278 P FGG++RT SE L + D W+ LP G DR+H CNP + + L Sbjct: 202 PGFGGSKRTGSELRLANDSRLPTFVLDLIWELSLPMGADRDHEYCNP-TAESEPLYSFDK 260 Query: 279 PKSL---VVVAGL--DLIRDWQLAYAEGLKKAGQEV 309 +SL V+V G D + D Q+ AE L+K G +V Sbjct: 261 IRSLGWRVMVVGCHGDPMIDRQMELAERLEKKGVDV 296 >4WY8-A nrPDB Length = 327 Score = 105 bits (263), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 65/221 (29%), Positives = 115/221 (52%), Gaps = 13/221 (5%) Query: 95 LDLEKPVDGD--IVPVILFFHGGSFAHSSA---NSAIYDTLCRRLVGLCKCVVVSVNYRR 149 L + +P+D + ++P I+FFHGG + S +Y+ R + V+ VNY Sbjct: 68 LTITRPLDTENQVLPPIVFFHGGGWVVGSKLTHRRTVYELTVR-----ARAAVIFVNYSL 122 Query: 150 APENPYPCAYDDGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGGNIAHNVALRAGESGI 209 +PE +P A ++ A+ WV KS + +AGDS+GGN++ V +RA + G+ Sbjct: 123 SPEVRFPTALEECLDAVVWVAKEENAKSINVDPTKLVVAGDSAGGNLSAVVCIRAKQLGL 182 Query: 210 DVL-GNILLNPMFGGNERTESEKSLDGKYFVTVRDRDWYWKAFLPEGEDREHPACNPFSP 268 +++ G +L+ P+ N T+S K Y++T + W++ ++P+ +DR+ P Sbjct: 183 NIIKGQVLIYPVTDDNFETDSYKQFAENYYLTRKLMVWFFDHYIPDKKDRQSIFACPLKA 242 Query: 269 RGKSLEGVSFPKSLVVVAGLDLIRDWQLAYAEGLKKAGQEV 309 L P++LV+ A D++R+ AYA L +AG +V Sbjct: 243 SIDDLR--VLPRALVITAEADVLREEGEAYARKLIEAGNDV 281 >3AIM-A nrPDB Length = 323 Score = 105 bits (261), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 70/214 (32%), Positives = 106/214 (49%), Gaps = 10/214 (4%) Query: 108 VILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRAPENPYPCAYDDGWIALN 167 V++++HGG F S YD LCR + C+CV +SV+YR APEN +P A D + AL Sbjct: 92 VLVYYHGGGFVLGDIES--YDPLCRAITNSCQCVTISVDYRLAPENKFPAAVVDSFDALK 149 Query: 168 WVNSRSWLKSKKDSKVHIFLAGDSSGGNIAHNVALRAGESGIDVLGNILLNPMFGGNERT 227 WV + S K + K I + GDS+GGN+A A+ + + I + +L+ P + T Sbjct: 150 WVYNNS---EKFNGKYGIAVGGDSAGGNLAAVTAILSKKENIKLKYQVLIYPAVSFDLIT 206 Query: 228 ESEKSLDGKYFVTVRDRDWYWKAFLPEGEDREHPACNPFSPRGKSLEGVSFPKSLVVVAG 287 +S +F+T DW+ + +L D FSP L P +L++ A Sbjct: 207 KSLYDNGEGFFLTREHIDWFGQQYLRSFADLLD---FRFSPILADLN--DLPPALIITAE 261 Query: 288 LDLIRDWQLAYAEGLKKAGQEVKLMHLEKATVGF 321 D +RD AYA L ++G +V + GF Sbjct: 262 HDPLRDQGEAYANKLLQSGVQVTSVEFNNVIHGF 295 >4V2I-A nrPDB Length = 323 Score = 103 bits (258), Expect = 9e-23, Method: Compositional matrix adjust. Identities = 68/222 (30%), Positives = 105/222 (47%), Gaps = 7/222 (3%) Query: 104 DIVPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRAPENPYPCAYDDGW 163 D +PVI++FHG + ++ +D L R L +V V+Y R+PE YP A + + Sbjct: 75 DRLPVIVYFHGAGWVM--GDTGTHDRLVRELSVRANAALVFVDYERSPEARYPVAIEQDY 132 Query: 164 IALNWVNSRSWLKSKKDSKVHIFLAGDSSGGNIAHNVALRAGE-SGIDVLGNILLNPMFG 222 +V S + +++ I AGDS GGN+ V+L A E G D+ +L P+ Sbjct: 133 AVTKYVAEHSEQLNVDPTRLAI--AGDSVGGNMTAVVSLLAQERGGPDITAQVLFYPVTD 190 Query: 223 GNERTESEKSLDGKYFVTVRDRDWYWKAFLPEGEDREHPACNPFSPRGKSLEGVSFPKSL 282 + S ++T DW+W +LPEG DR P P + L G + +L Sbjct: 191 ADFDNGSYTEFANGPWLTKPAMDWFWNQYLPEGIDRTDPKITPIHATSEQLSGQA--PAL 248 Query: 283 VVVAGLDLIRDWQLAYAEGLKKAGQEVKLMHLEKATVGFYLL 324 V+ A D++RD AYA L +AG +V + F +L Sbjct: 249 VITAENDVLRDEGEAYARKLSQAGVDVTVTRYNGTIHDFVML 290 >2YH2-A nrPDB Length = 313 Score = 97.4 bits (241), Expect = 8e-21, Method: Compositional matrix adjust. Identities = 72/242 (29%), Positives = 118/242 (48%), Gaps = 19/242 (7%) Query: 99 KPVDGDIVPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRAPENPYPCA 158 +P DG+ +P ++++HGG F S + +D +CRRL L VVVSV+YR APE+ +P A Sbjct: 69 RPRDGERLPAVVYYHGGGFVLGSVET--HDHVCRRLANLSGAVVVSVDYRLAPEHKFPAA 126 Query: 159 YDDGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGGNIAHNVALRAGESGIDVLG-NILL 217 +D + A WV + ++ K D+ I +AGDS+GGN+A A+ A + G + +L+ Sbjct: 127 VEDAYDAAKWV-ADNYDKLGVDNG-KIAVAGDSAGGNLAAVTAIMARDRGESFVKYQVLI 184 Query: 218 NP---MFGGNERTESEKSLDGKYFVTVRDRDWYWKAFLPEGEDREHPACNPFSPRGKSLE 274 P + G + E S +T W+ + + + +D P +P +L Sbjct: 185 YPAVNLTGSPTVSRVEYSGPEYVILTADLMAWFGRQYFSKPQDALSPYASPIFADLSNL- 243 Query: 275 GVSFPKSLVVVAGLDLIRDWQLAYAEGLKKAGQEVKLMHLEKATVGFYLLPNNNHFHNVM 334 P +LV+ A D +RD YA LK G + GF +F+ ++ Sbjct: 244 ----PPALVITAEYDPLRDEGELYAHLLKTRGVRAVAVRYNGVIHGFV------NFYPIL 293 Query: 335 DE 336 +E Sbjct: 294 EE 295 >2C7B-A nrPDB Length = 311 Score = 90.5 bits (223), Expect = 9e-19, Method: Compositional matrix adjust. Identities = 72/225 (32%), Positives = 108/225 (48%), Gaps = 18/225 (8%) Query: 106 VPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRAPENPYPCAYDDGWIA 165 +P +L++HGG F S + +D +CRRL L VVVSV+YR APE +P A +D + A Sbjct: 73 LPAVLYYHGGGFVFGSIET--HDHICRRLSRLSDSVVVSVDYRLAPEYKFPTAVEDAYAA 130 Query: 166 LNWVNSRS-WLKSKKDSKVHIFLAGDSSGGNIAHNVALRAGESGIDVL-GNILLNP---M 220 L WV R+ L D I +AGDS+GGN+A V++ SG ++ +L+ P M Sbjct: 131 LKWVADRADELGVDPD---RIAVAGDSAGGNLAAVVSILDRNSGEKLVKKQVLIYPVVNM 187 Query: 221 FGGNERTESEKSLDGKYFVTVRDRDWYWKAFLPEGEDREHPACNPFSPRGKSLEGVSFPK 280 G + E + + + W+ + +L E+ +P L G P Sbjct: 188 TGVPTASLVEFGVAETTSLPIELMVWFGRQYLKRPEEAYDFKASPLL---ADLGG--LPP 242 Query: 281 SLVVVAGLDLIRDWQLAYAEGLKKAGQE---VKLMHLEKATVGFY 322 +LVV A D +RD YA +K +G V+ + V FY Sbjct: 243 ALVVTAEYDPLRDEGELYAYKMKASGSRAVAVRFAGMVHGFVSFY 287 >4WY5-A nrPDB Length = 332 Score = 83.2 bits (204), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 65/229 (28%), Positives = 109/229 (47%), Gaps = 11/229 (4%) Query: 102 DGDIVPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRAPENPYPCAYDD 161 + I+PV++F HGG F S + I R L V V V+Y +PE +P A ++ Sbjct: 76 EDQILPVLIFLHGGGFVFGSKYTHIKP--VRDLTVKANVVTVFVDYSLSPEAKFPTAIEE 133 Query: 162 GWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGGNIAHNVALRAGESGID--VLGNILLNP 219 + A+ WV R S + + +AGDS+G ++ V++ A E G+ + +L+ P Sbjct: 134 IYAAILWV--RENASSLNINAEALAVAGDSAGATLSAAVSIYAKEKGLSAAIKTQVLIYP 191 Query: 220 MFG-GNERTESEKSL-DGKYFVTVRDRDWYWKAFLPEGEDREHPACNPFSPRGKS-LEGV 276 + + ES K +G Y ++ D ++ A+LP + K+ LEG Sbjct: 192 ATAVSHAKYESYKLFGNGDYILSAEDLKFFSNAYLPAPASELNDKLATLELATKADLEG- 250 Query: 277 SFPKSLVVVAGLDLIRDWQLAYAEGLKKAGQEVKLMHLEKATVGFYLLP 325 P +L+ A D++RD YA+ L +AG +V + + A GF +P Sbjct: 251 -LPPALLFTAESDVLRDEGEKYAQQLAEAGVDVAAVRVLGAVHGFITVP 298 >6AAE-A nrPDB Length = 317 Score = 80.1 bits (196), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 63/229 (27%), Positives = 105/229 (45%), Gaps = 11/229 (4%) Query: 97 LEKPVDGDIVPVIL-FFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRAPENPY 155 L P D D P ++ ++HGG + + ++ +D CR L C V+S+ YR APE Y Sbjct: 62 LYVPEDADERPALMVYYHGGGWVIGTLDT--HDGTCRALAQKSGCAVLSIAYRLAPEYRY 119 Query: 156 PCAYDDGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGGNIAHNVALRAGESGIDVLGNI 215 P +D + AL W + ++ + GDS+GGN+A VA+ A + L + Sbjct: 120 PAPAEDCYDALVWAKQNAATLGVDGDRLAV--GGDSAGGNLAAAVAIMARDRNGPALRHQ 177 Query: 216 LLNPMFGGNERTESEKSLD--GKYFVTVRDRDWYWKAFLPEGEDREHPACNPFSPRGKSL 273 LL N+ T + + + G+Y+++ W+W +L + P + L Sbjct: 178 LLIYPVTDNDFTLASYAENGGGEYYLSTDGMRWFWGHYLGDTAAENAPLAAVLNV--ADL 235 Query: 274 EGVSFPKSLVVVAGLDLIRDWQLAYAEGLKKAGQEVKLMHLEKATVGFY 322 G++ + V+ A D +RD +AYA+ L AG V GF+ Sbjct: 236 SGLA--PATVITAEYDPLRDEGIAYAKKLDAAGVPVDAATAPGMIHGFF 282 >5L2P-A nrPDB Length = 306 Score = 76.6 bits (187), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 54/200 (27%), Positives = 97/200 (48%), Gaps = 9/200 (4%) Query: 108 VILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRAPENPYPCAYDDGWIALN 167 +++ FHGG++ S + D + R L C+C V+SV+YR APE +P A D + A+ Sbjct: 77 LVMHFHGGAWILGSIETE--DAISRILSNSCECTVISVDYRLAPEYKFPTAVYDCFNAIV 134 Query: 168 WVNSRSWLKSKKDSKVHIFLAGDSSGGNIAHNVALRAGESGIDVLGNILLNPMFGGNERT 227 W + K+ F G S+GGN+ +L A ++ + + + + P + + Sbjct: 135 WARDNAGELGIDKDKIATF--GISAGGNLVAATSLLARDNKLKLTAQVPVVPFVYLDLAS 192 Query: 228 ESEKSLDGKYFVTVR-DRDWYWKAFLPEGEDREHPACNPFSPRGKSLEGVSFPKSLVVVA 286 +S YF+ + D+ K ++ + +D +P +P S + P+++VV A Sbjct: 193 KSMNRYRKGYFLDINLPVDYGVKMYIRDEKDLYNPLFSPLIAEDLS----NLPQAIVVTA 248 Query: 287 GLDLIRDWQLAYAEGLKKAG 306 D +RD AYA L ++G Sbjct: 249 EYDPLRDQGEAYAYRLMESG 268 >3WJ2-A nrPDB Length = 308 Score = 74.7 bits (182), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 53/208 (25%), Positives = 97/208 (46%), Gaps = 14/208 (6%) Query: 102 DGDIVPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRAPENPYPCAYDD 161 D + IL++HGG F N YD CR L ++S+ YR APE+ +P A++D Sbjct: 72 DNNAKSAILYYHGGGFLF--GNIETYDNYCRFLAKESGVKIISIEYRLAPEHKFPDAFND 129 Query: 162 GWIALNWVNSRSWLKSKKDSKVH--IFLAGDSSGGNIAHNVALRAGESGIDVLG-NILLN 218 + + +++ K KKD + I +AGDS+G N+A + L+ + ++ +L Sbjct: 130 AYDSFHYI-----AKKKKDFGIEGRIGVAGDSAGANLAAALCLKCRDGKTEMPAVQVLFY 184 Query: 219 PMFGGNERTESEKSLDGKYFVTVRDRDWYWKAFLPEGEDREHPACNPFSPRGKSLEGVSF 278 P + + S Y +T + ++ + +D +P +P S + Sbjct: 185 PSLAPDNFSRSFIEYSDNYVLTGKMIRYFGNMYSKNMQDLINPYFSPLVADDFS----NL 240 Query: 279 PKSLVVVAGLDLIRDWQLAYAEGLKKAG 306 P +++V D +RD + Y + L++AG Sbjct: 241 PPAIMVTNEYDPLRDPEETYVKKLREAG 268 >4KRY-A nrPDB Length = 333 Score = 53.5 bits (127), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 44/160 (27%), Positives = 79/160 (49%), Gaps = 10/160 (6%) Query: 107 PVILFF-HGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRAPENPYPCAYDDGWIA 165 P LF+ HGG F + ++ +D + R L +C V+ ++Y +PE +P A ++ A Sbjct: 98 PATLFYLHGGGFILGNLDT--HDRIMRLLASYSQCTVIGIDYTLSPEARFPQAIEEIVAA 155 Query: 166 LNWVNSRSWLKSKKDSKVHIFLAGDSSGGNIAHNVALRAGESGID---VLGNILLNPMFG 222 + + ++ + + + I AGDS+G +A AL + ID V G +L ++G Sbjct: 156 CCYFHQQA--EDYQINMSRIGFAGDSAGAMLALASALWLRDKQIDCGKVAGVLLWYGLYG 213 Query: 223 GNERTESEKSLDGKY-FVTVRDRDWYWKAFLPEGEDREHP 261 + + + L G + +T +D Y +A+L DRE P Sbjct: 214 LRDSV-TRRLLGGVWDGLTQQDLQMYEEAYLSNDADRESP 252 >3GA7-A nrPDB Length = 326 Score = 50.8 bits (120), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 47/158 (29%), Positives = 71/158 (44%), Gaps = 9/158 (5%) Query: 108 VILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRAPENPYPCAYDDGWIALN 167 + + HGG F N +D + R L C V+ ++Y +P+ YP A ++ + Sbjct: 89 TLYYLHGGGFI--LGNLDTHDRIMRLLARYTGCTVIGIDYSLSPQARYPQAIEETVAVCS 146 Query: 168 WVNSRSWLKSKKDSKVHIFLAGDSSGGNIAHNVALRAGESGIDVLGN---ILLNPMFGGN 224 + + + S K I AGDS+G +A AL + I GN ILL G Sbjct: 147 YFSQHADEYSLNVEK--IGFAGDSAGAMLALASALWLRDKHIRC-GNVIAILLWYGLYGL 203 Query: 225 ERTESEKSLDGKY-FVTVRDRDWYWKAFLPEGEDREHP 261 + + S + G + +T D D Y KA+L EDRE P Sbjct: 204 QDSVSRRLFGGAWDGLTREDLDMYEKAYLRNDEDRESP 241 >1C7J-A nrPDB Length = 489 Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust. Identities = 30/113 (26%), Positives = 57/113 (50%), Gaps = 16/113 (14%) Query: 106 VPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRAP-----ENPYPCAYD 160 +PV+++ HGG+F + + +YD +L + +VV++NYR P + + AY Sbjct: 97 LPVMVWIHGGAFYLGAGSEPLYD--GSKLAAQGEVIVVTLNYRLGPFGFMHLSSFDEAYS 154 Query: 161 DGWIALNWVNSRSWLKSKKDS------KVHIFLAGDSSGG-NIAHNVALRAGE 206 D L+ + W++ + V +F G+S+GG +IA +A+ A + Sbjct: 155 DNLGLLDQAAALKWVRENISAFGGDPDNVTVF--GESAGGMSIAALLAMPAAK 205 >1THG-A nrPDB Length = 544 Score = 35.0 bits (79), Expect = 0.045, Method: Compositional matrix adjust. Identities = 29/115 (25%), Positives = 53/115 (46%), Gaps = 15/115 (13%) Query: 106 VPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVV-VSVNYRRAP-----------EN 153 +PV+++ +GG+F + S+ + ++ + + + + VV VS+NYR P E Sbjct: 122 LPVMVWIYGGAFVYGSSAAYPGNSYVKESINMGQPVVFVSINYRTGPFGFLGGDAITAEG 181 Query: 154 PYPCAYDDGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGG-NIAHNVALRAGES 207 D L WV+ KV IF G+S+G ++AH + G++ Sbjct: 182 NTNAGLHDQRKGLEWVSDNIANFGGDPDKVMIF--GESAGAMSVAHQLIAYGGDN 234 >5THM-A nrPDB Length = 533 Score = 35.0 bits (79), Expect = 0.046, Method: Compositional matrix adjust. Identities = 28/106 (26%), Positives = 45/106 (42%), Gaps = 15/106 (14%) Query: 107 PVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRAP-------ENPYPCAY 159 PV+ HGG+F +A ++ + R K ++V ++YR P + P Y Sbjct: 111 PVVAHIHGGAFMFGAAWQNGHENVMRE----GKFILVKISYRLGPLGFLSTGDRDLPGNY 166 Query: 160 --DDGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGGNIAHNVALR 203 D +AL W+ + S ++ L G S+GG H LR Sbjct: 167 GLKDQRLALKWIKQN--IASFGGEPQNVLLVGHSAGGASVHLQMLR 210 >5YDJ-A nrPDB Length = 737 Score = 34.7 bits (78), Expect = 0.062, Method: Compositional matrix adjust. Identities = 30/95 (31%), Positives = 41/95 (43%), Gaps = 13/95 (13%) Query: 108 VILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRA---------PENPYPCA 158 V+L+ GG F +A +YD R L +VVS+ YR A PE P Sbjct: 272 VMLWIFGGGFYSGTATLDVYDH--RALASEENVIVVSLQYRVASLGFLFLGTPEAPGNAG 329 Query: 159 YDDGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSG 193 D +AL WV S+V +F G+S+G Sbjct: 330 LFDQNLALRWVRDNIHRFGGDPSRVTLF--GESAG 362 >2X8B-A nrPDB Length = 583 Score = 33.9 bits (76), Expect = 0.096, Method: Compositional matrix adjust. Identities = 28/98 (28%), Positives = 44/98 (44%), Gaps = 14/98 (14%) Query: 106 VPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRAP----------ENPY 155 PV+++ +GG F +++ +YD R LV + V+VS+NYR E P Sbjct: 112 TPVLVWIYGGGFYSGASSLDVYDG--RFLVQAERTVLVSMNYRVGAFGFLALPGSREAPG 169 Query: 156 PCAYDDGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSG 193 D +AL WV + V +F G+S+G Sbjct: 170 NVGLLDQRLALQWVQENVAAFGGDPTSVTLF--GESAG 205 >5YDI-A nrPDB Length = 553 Score = 33.9 bits (76), Expect = 0.098, Method: Compositional matrix adjust. Identities = 30/96 (31%), Positives = 41/96 (42%), Gaps = 13/96 (13%) Query: 108 VILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRA---------PENPYPCA 158 V+L+ GG F +A +YD R L +VVS+ YR A PE P Sbjct: 111 VMLWIFGGGFYSGTATLDVYDH--RALASEENVIVVSLQYRVASLGFLFLGTPEAPGNAG 168 Query: 159 YDDGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGG 194 D +AL WV S+V +F G+S+G Sbjct: 169 LFDQNLALRWVRDNIHRFGGDPSRVTLF--GESAGA 202 >1Q83-A nrPDB Length = 580 Score = 33.9 bits (76), Expect = 0.099, Method: Compositional matrix adjust. Identities = 28/104 (26%), Positives = 45/104 (43%), Gaps = 14/104 (13%) Query: 100 PVDGDIVPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRAP-------- 151 P PV+++ +GG F +A+ +YD R L + V+VS+NYR Sbjct: 137 PRPASPTPVLIWIYGGGFYSGAASLDVYDG--RFLAQVEGAVLVSMNYRVGTFGFLALPG 194 Query: 152 --ENPYPCAYDDGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSG 193 E P D +AL WV + + + + L G+S+G Sbjct: 195 SREAPGNVGLLDQRLALQWVQEN--IAAFGGDPMSVTLFGESAG 236 >6QAA-A nrPDB Length = 557 Score = 33.1 bits (74), Expect = 0.16, Method: Compositional matrix adjust. Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 14/97 (14%) Query: 108 VILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRA----------PENPYPC 157 V+++ +GG F +++ +YD + L + + +VVS+NYR PE P Sbjct: 137 VLIWIYGGGFQTGTSSLHVYDG--KFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNM 194 Query: 158 AYDDGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGG 194 D +AL WV V +F G+S+G Sbjct: 195 GLFDQQLALQWVQKNIAAFGGNPKSVTLF--GESAGA 229 >3BIX-A nrPDB Length = 574 Score = 32.7 bits (73), Expect = 0.26, Method: Compositional matrix adjust. Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 10/68 (14%) Query: 87 DQEQPPSILDLEKPVDGDI------VPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKC 140 DQ + L++ P + DI PV+++ HGGS+ + N +YD L Sbjct: 106 DQSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIHGGSYMEGTGN--LYDGSV--LASYGNV 161 Query: 141 VVVSVNYR 148 +V++VNYR Sbjct: 162 IVITVNYR 169 >4QWW-A nrPDB Length = 542 Score = 32.3 bits (72), Expect = 0.30, Method: Compositional matrix adjust. Identities = 26/98 (26%), Positives = 44/98 (44%), Gaps = 14/98 (14%) Query: 106 VPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYR----------RAPENPY 155 PV+++ +GG F +A+ +YD R L ++VS++YR +PE P Sbjct: 109 APVLVWIYGGGFYSGAASLDVYDG--RFLTYTQNVILVSLSYRVGAFGFLGLPGSPEAPG 166 Query: 156 PCAYDDGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSG 193 D +AL W+ + V +F G+S+G Sbjct: 167 NMGLLDQRLALQWIQNNIHPFGGNPRAVTVF--GESAG 202 >4XHP-A nrPDB Length = 866 Score = 31.6 bits (70), Expect = 0.53, Method: Compositional matrix adjust. Identities = 20/62 (32%), Positives = 27/62 (43%), Gaps = 11/62 (17%) Query: 232 SLDGKYFVTVRDRDWYWKAFLPEGEDREHPAC-------NPFSPRGKSLEGVSFPKSLVV 284 SLDG R R WY A+ + EDR+ P + FS + K L + S+ V Sbjct: 81 SLDG----DARSRAWYVGAYAKDQEDRQEPTVDEMGKTEDKFSQKNKKLHLIPLFTSMAV 136 Query: 285 VA 286 A Sbjct: 137 AA 138 Score = 31.6 bits (70), Expect = 0.53, Method: Compositional matrix adjust. Identities = 20/62 (32%), Positives = 27/62 (43%), Gaps = 11/62 (17%) Query: 232 SLDGKYFVTVRDRDWYWKAFLPEGEDREHPAC-------NPFSPRGKSLEGVSFPKSLVV 284 SLDG R R WY A+ + EDR+ P + FS + K L + S+ V Sbjct: 524 SLDG----DARSRAWYVGAYAKDQEDRQEPTVDEMGKTEDKFSQKNKKLHLIPLFTSMAV 579 Query: 285 VA 286 A Sbjct: 580 AA 581 >4XHO-A nrPDB Length = 423 Score = 31.6 bits (70), Expect = 0.53, Method: Compositional matrix adjust. Identities = 20/62 (32%), Positives = 27/62 (43%), Gaps = 11/62 (17%) Query: 232 SLDGKYFVTVRDRDWYWKAFLPEGEDREHPAC-------NPFSPRGKSLEGVSFPKSLVV 284 SLDG R R WY A+ + EDR+ P + FS + K L + S+ V Sbjct: 81 SLDG----DARSRAWYVGAYAKDQEDRQEPTVDEMGKTEDKFSQKNKKLHLIPLFTSMAV 136 Query: 285 VA 286 A Sbjct: 137 AA 138 >5V5V-A nrPDB Length = 582 Score = 30.8 bits (68), Expect = 0.81, Method: Compositional matrix adjust. Identities = 19/54 (35%), Positives = 27/54 (50%), Gaps = 9/54 (16%) Query: 100 PVDGDI-----VPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYR 148 P D DI PV+LF HGGS+ + N ++D L +V ++NYR Sbjct: 126 PPDTDIRDSGKKPVMLFLHGGSYMEGTGN--MFDGSV--LAAYGNVIVATLNYR 175 >1IKQ-A nrPDB Length = 613 Score = 29.6 bits (65), Expect = 1.7, Method: Compositional matrix adjust. Identities = 42/172 (24%), Positives = 68/172 (39%), Gaps = 39/172 (22%) Query: 42 NRHLAEYLDRKVTANANPVDGVFSFDVLIDRRINL----LSRVYRPAYADQEQPPSILDL 97 + +E+ KV +P+DGV+++ L +R NL ++YR + P+ DL Sbjct: 184 EKRWSEWASGKVLCLLDPLDGVYNY--LAQQRCNLDDTWEGKIYRVLAGN----PAKHDL 237 Query: 98 EKPVDGDIVPVIL-----FFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRAP- 151 DI P ++ F GGS A +A+ A C + + R P Sbjct: 238 ------DIKPTVISHRLHFPEGGSLAALTAHQA------------CHLPLETFTRHRQPR 279 Query: 152 --ENPYPCAYD-DGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGGNIAHNV 200 E C Y +AL SW ++ D + LA SGG++ + Sbjct: 280 GWEQLEQCGYPVQRLVALYLAARLSW--NQVDQVIRNALASPGSGGDLGEAI 329 >2WQZ-A nrPDB Length = 588 Score = 29.3 bits (64), Expect = 2.6, Method: Compositional matrix adjust. Identities = 19/68 (27%), Positives = 34/68 (50%), Gaps = 10/68 (14%) Query: 87 DQEQPPSILDLEKPVDGDI------VPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKC 140 DQ + L++ P + DI PV+++ HGGS+ + N I ++ L Sbjct: 110 DQNEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGN-MIDGSI---LASYGNV 165 Query: 141 VVVSVNYR 148 +V+++NYR Sbjct: 166 IVITINYR 173 >4YE5-A nrPDB Length = 566 Score = 29.3 bits (64), Expect = 3.0, Method: Compositional matrix adjust. Identities = 17/62 (27%), Positives = 30/62 (48%), Gaps = 13/62 (20%) Query: 203 RAGESGIDVLGNILLNPMFGGNERTESEKSLDGKYFVTVRDRD--WYWKAFLPEGEDREH 260 + G SG+++ G + TES+ +++G DRD WY + L + E++ H Sbjct: 191 QQGNSGVEIPGTM-----------TESKDAVNGSDVTLTIDRDVQWYTEKVLSDSENKYH 239 Query: 261 PA 262 A Sbjct: 240 SA 241 >1QON-A nrPDB Length = 585 Score = 28.1 bits (61), Expect = 5.6, Method: Compositional matrix adjust. Identities = 14/43 (32%), Positives = 22/43 (51%), Gaps = 2/43 (4%) Query: 106 VPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYR 148 +P++++ +GG F SA IY+ VG +V S YR Sbjct: 141 LPILIWIYGGGFMTGSATLDIYNADIMAAVG--NVIVASFQYR 181 >4A39-A nrPDB Length = 388 Score = 28.1 bits (61), Expect = 6.4, Method: Compositional matrix adjust. Identities = 23/81 (28%), Positives = 38/81 (46%), Gaps = 3/81 (3%) Query: 34 LRRPDGTFNRHLAEYLDRKVTANANPVDGVFSFDVLIDRRINLLSRVYRPAYADQEQPPS 93 L+RPD T + L E D + N NP DG F ++ + L+R + A E+ P Sbjct: 197 LQRPDDTEMQRLLEKADLYLVPNMNP-DGAFHGNLRTNAAGQDLNRAWLEPSA--ERSPE 253 Query: 94 ILDLEKPVDGDIVPVILFFHG 114 + +++ + V + L HG Sbjct: 254 VWFVQQEMKRHGVDLFLDIHG 274 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2ZSH-A nrPDB 516 e-147 3EBL-A nrPDB 487 e-138 2YH2-A nrPDB 280 1e-75 4WY8-A nrPDB 276 1e-74 3AIM-A nrPDB 270 6e-73 4V2I-A nrPDB 268 2e-72 2C7B-A nrPDB 254 3e-68 6AAE-A nrPDB 248 4e-66 5L2P-A nrPDB 246 1e-65 3WJ2-A nrPDB 242 1e-64 4WY5-A nrPDB 236 8e-63 2O7R-A nrPDB 217 7e-57 3GA7-A nrPDB 196 1e-50 4KRY-A nrPDB 195 2e-50 Sequences not found previously or not previously below threshold: 5AOA-A nrPDB 82 5e-16 1C7J-A nrPDB 63 2e-10 1MX5-A nrPDB 60 1e-09 5FV4-A nrPDB 59 3e-09 1K4Y-A nrPDB 57 1e-08 1Q83-A nrPDB 55 4e-08 4Q3K-A nrPDB 55 5e-08 5YDJ-A nrPDB 54 1e-07 5YDI-A nrPDB 53 2e-07 5THM-A nrPDB 53 2e-07 2X8B-A nrPDB 53 2e-07 6EMI-A nrPDB 52 3e-07 4QWW-A nrPDB 52 3e-07 1THG-A nrPDB 52 5e-07 6QAA-A nrPDB 51 7e-07 3BIX-A nrPDB 50 2e-06 2WQZ-A nrPDB 49 4e-06 6H18-A nrPDB 48 7e-06 1VKH-A nrPDB 46 3e-05 1QON-A nrPDB 45 4e-05 1AKN-A nrPDB 44 1e-04 2W6C-X nrPDB 44 2e-04 5V5V-A nrPDB 43 2e-04 1GZ7-A nrPDB 40 0.002 1LLF-A nrPDB 38 0.004 3RAR-A nrPDB 38 0.004 4BZW-A nrPDB 37 0.009 5HQ3-A nrPDB 37 0.015 5L8S-A nrPDB 35 0.047 3HXK-A nrPDB 32 0.33 3C5W-P nrPDB 31 0.98 6FVJ-A nrPDB 30 1.4 4HXF-B nrPDB 30 1.6 1HP5-A nrPDB 30 2.0 2ORY-A nrPDB 30 2.0 2EQ5-A nrPDB 30 2.0 4LMA-A nrPDB 28 5.5 5D3Z-A nrPDB 28 5.8 6MLK-A nrPDB 28 5.9 4C7D-A nrPDB 28 6.4 3P1V-A nrPDB 28 6.6 6DAO-B nrPDB 28 6.7 5LF8-A nrPDB 28 6.9 1XRN-A nrPDB 28 7.2 3JWE-A nrPDB 28 7.3 4B6G-A nrPDB 28 7.7 2EBA-A nrPDB 28 7.9 5HFN-A nrPDB 28 8.3 3O4I-A nrPDB 27 8.8 5FDF-A nrPDB 27 8.9 2JH3-A nrPDB 27 9.0 2X26-A nrPDB 27 9.5 >2ZSH-A nrPDB Length = 351 Score = 516 bits (1329), Expect = e-147, Method: Composition-based stats. Identities = 344/344 (100%), Positives = 344/344 (100%) Query: 1 MAASDEVNLIESRTVVPLNTWVLISNFKVAYNILRRPDGTFNRHLAEYLDRKVTANANPV 60 MAASDEVNLIESRTVVPLNTWVLISNFKVAYNILRRPDGTFNRHLAEYLDRKVTANANPV Sbjct: 8 MAASDEVNLIESRTVVPLNTWVLISNFKVAYNILRRPDGTFNRHLAEYLDRKVTANANPV 67 Query: 61 DGVFSFDVLIDRRINLLSRVYRPAYADQEQPPSILDLEKPVDGDIVPVILFFHGGSFAHS 120 DGVFSFDVLIDRRINLLSRVYRPAYADQEQPPSILDLEKPVDGDIVPVILFFHGGSFAHS Sbjct: 68 DGVFSFDVLIDRRINLLSRVYRPAYADQEQPPSILDLEKPVDGDIVPVILFFHGGSFAHS 127 Query: 121 SANSAIYDTLCRRLVGLCKCVVVSVNYRRAPENPYPCAYDDGWIALNWVNSRSWLKSKKD 180 SANSAIYDTLCRRLVGLCKCVVVSVNYRRAPENPYPCAYDDGWIALNWVNSRSWLKSKKD Sbjct: 128 SANSAIYDTLCRRLVGLCKCVVVSVNYRRAPENPYPCAYDDGWIALNWVNSRSWLKSKKD 187 Query: 181 SKVHIFLAGDSSGGNIAHNVALRAGESGIDVLGNILLNPMFGGNERTESEKSLDGKYFVT 240 SKVHIFLAGDSSGGNIAHNVALRAGESGIDVLGNILLNPMFGGNERTESEKSLDGKYFVT Sbjct: 188 SKVHIFLAGDSSGGNIAHNVALRAGESGIDVLGNILLNPMFGGNERTESEKSLDGKYFVT 247 Query: 241 VRDRDWYWKAFLPEGEDREHPACNPFSPRGKSLEGVSFPKSLVVVAGLDLIRDWQLAYAE 300 VRDRDWYWKAFLPEGEDREHPACNPFSPRGKSLEGVSFPKSLVVVAGLDLIRDWQLAYAE Sbjct: 248 VRDRDWYWKAFLPEGEDREHPACNPFSPRGKSLEGVSFPKSLVVVAGLDLIRDWQLAYAE 307 Query: 301 GLKKAGQEVKLMHLEKATVGFYLLPNNNHFHNVMDEISAFVNAE 344 GLKKAGQEVKLMHLEKATVGFYLLPNNNHFHNVMDEISAFVNAE Sbjct: 308 GLKKAGQEVKLMHLEKATVGFYLLPNNNHFHNVMDEISAFVNAE 351 >3EBL-A nrPDB Length = 365 Score = 487 bits (1254), Expect = e-138, Method: Composition-based stats. Identities = 216/350 (61%), Positives = 267/350 (76%), Gaps = 9/350 (2%) Query: 2 AASDEVNLIESRTVVPLNTWVLISNFKVAYNILRRPDGTFNRHLAEYLDRKVTANANPVD 61 A SDEVN E +TVVPL+TWVLISNFK++YNILRR DGTF R L EYLDR+V ANA P++ Sbjct: 1 AGSDEVNRNECKTVVPLHTWVLISNFKLSYNILRRADGTFERDLGEYLDRRVPANARPLE 60 Query: 62 GVFSFDVLIDRRINLLSRVYRPAYADQEQPPSILDLEKPV--------DGDIVPVILFFH 113 GV SFD +ID+ + L R+YR A A+ + + +P+ + PVI+FFH Sbjct: 61 GVSSFDHIIDQSVGLEVRIYRAA-AEGDAEEGAAAVTRPILEFLTDAPAAEPFPVIIFFH 119 Query: 114 GGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRAPENPYPCAYDDGWIALNWVNSRS 173 GGSF HSSA+S IYD+LCRR V L K VVVSVNYRRAPE+ YPCAYDDGW AL WV S+ Sbjct: 120 GGSFVHSSASSTIYDSLCRRFVKLSKGVVVSVNYRRAPEHRYPCAYDDGWTALKWVMSQP 179 Query: 174 WLKSKKDSKVHIFLAGDSSGGNIAHNVALRAGESGIDVLGNILLNPMFGGNERTESEKSL 233 +++S D++ +FL+GDSSGGNIAH+VA+RA + G+ V GNILLN MFGG ERTESE+ L Sbjct: 180 FMRSGGDAQARVFLSGDSSGGNIAHHVAVRAADEGVKVCGNILLNAMFGGTERTESERRL 239 Query: 234 DGKYFVTVRDRDWYWKAFLPEGEDREHPACNPFSPRGKSLEGVSFPKSLVVVAGLDLIRD 293 DGKYFVT++DRDWYWKA+LPE DR+HPACNPF P G+ L G+ F KSL++V+GLDL D Sbjct: 240 DGKYFVTLQDRDWYWKAYLPEDADRDHPACNPFGPNGRRLGGLPFAKSLIIVSGLDLTCD 299 Query: 294 WQLAYAEGLKKAGQEVKLMHLEKATVGFYLLPNNNHFHNVMDEISAFVNA 343 QLAYA+ L++ G VK++ E ATVGFYLLPN H+H VM+EIS F+NA Sbjct: 300 RQLAYADALREDGHHVKVVQCENATVGFYLLPNTVHYHEVMEEISDFLNA 349 >2YH2-A nrPDB Length = 313 Score = 280 bits (715), Expect = 1e-75, Method: Composition-based stats. Identities = 73/253 (28%), Positives = 116/253 (45%), Gaps = 19/253 (7%) Query: 88 QEQPPSILDLEKPVDGDIVPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNY 147 P + +P DG+ +P ++++HGG F S + +D +CRRL L VVVSV+Y Sbjct: 58 GRGGPIRARVYRPRDGERLPAVVYYHGGGFVLGSVET--HDHVCRRLANLSGAVVVSVDY 115 Query: 148 RRAPENPYPCAYDDGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGGNIAHNVALRAGES 207 R APE+ +P A +D + A WV + K I +AGDS+GGN+A A+ A + Sbjct: 116 RLAPEHKFPAAVEDAYDAAKWVADNYDKLGVDNGK--IAVAGDSAGGNLAAVTAIMARDR 173 Query: 208 GID-VLGNILLNP---MFGGNERTESEKSLDGKYFVTVRDRDWYWKAFLPEGEDREHPAC 263 G V +L+ P + G + E S +T W+ + + + +D P Sbjct: 174 GESFVKYQVLIYPAVNLTGSPTVSRVEYSGPEYVILTADLMAWFGRQYFSKPQDALSPYA 233 Query: 264 NPFSPRGKSLEGVSFPKSLVVVAGLDLIRDWQLAYAEGLKKAGQEVKLMHLEKATVGFYL 323 +P +L P +LV+ A D +RD YA LK G + GF Sbjct: 234 SPIFADLSNL-----PPALVITAEYDPLRDEGELYAHLLKTRGVRAVAVRYNGVIHGFV- 287 Query: 324 LPNNNHFHNVMDE 336 +F+ +++E Sbjct: 288 -----NFYPILEE 295 >4WY8-A nrPDB Length = 327 Score = 276 bits (705), Expect = 1e-74, Method: Composition-based stats. Identities = 69/251 (27%), Positives = 126/251 (50%), Gaps = 8/251 (3%) Query: 95 LDLEKPVDGD--IVPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRAPE 152 L + +P+D + ++P I+FFHGG + S + + L + V+ VNY +PE Sbjct: 68 LTITRPLDTENQVLPPIVFFHGGGWVVGSKLT--HRRTVYELTVRARAAVIFVNYSLSPE 125 Query: 153 NPYPCAYDDGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGGNIAHNVALRAGESGIDVL 212 +P A ++ A+ WV KS + +AGDS+GGN++ V +RA + G++++ Sbjct: 126 VRFPTALEECLDAVVWVAKEENAKSINVDPTKLVVAGDSAGGNLSAVVCIRAKQLGLNII 185 Query: 213 -GNILLNPMFGGNERTESEKSLDGKYFVTVRDRDWYWKAFLPEGEDREHPACNPFSPRGK 271 G +L+ P+ N T+S K Y++T + W++ ++P+ +DR+ P Sbjct: 186 KGQVLIYPVTDDNFETDSYKQFAENYYLTRKLMVWFFDHYIPDKKDRQSIFACPLKASID 245 Query: 272 SLEGVSFPKSLVVVAGLDLIRDWQLAYAEGLKKAGQEVKLMHLEKATVGFYLLPN-NNHF 330 L P++LV+ A D++R+ AYA L +AG +V + G + L + Sbjct: 246 DLR--VLPRALVITAEADVLREEGEAYARKLIEAGNDVTAVRYLGIIHGIFNLATLSPTG 303 Query: 331 HNVMDEISAFV 341 ++D I A++ Sbjct: 304 SEILDHIVAWL 314 >3AIM-A nrPDB Length = 323 Score = 270 bits (691), Expect = 6e-73, Method: Composition-based stats. Identities = 70/242 (28%), Positives = 111/242 (45%), Gaps = 16/242 (6%) Query: 95 LDLEKPVDGDIVPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRAPENP 154 + P V++++HGG F S YD LCR + C+CV +SV+YR APEN Sbjct: 79 ARVYYPKTQGPYGVLVYYHGGGFVLGDIES--YDPLCRAITNSCQCVTISVDYRLAPENK 136 Query: 155 YPCAYDDGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGGNIAHNVALRAGESGIDVLGN 214 +P A D + AL WV + S K + K I + GDS+GGN+A A+ + + I + Sbjct: 137 FPAAVVDSFDALKWVYNNSE---KFNGKYGIAVGGDSAGGNLAAVTAILSKKENIKLKYQ 193 Query: 215 ILLNPMFGGNERTESEKSLDGKYFVTVRDRDWYWKAFLPEGEDREHPACNPFSPRGKSLE 274 +L+ P + T+S +F+T DW+ + +L D +P L Sbjct: 194 VLIYPAVSFDLITKSLYDNGEGFFLTREHIDWFGQQYLRSFADLLDFRFSPILADLNDL- 252 Query: 275 GVSFPKSLVVVAGLDLIRDWQLAYAEGLKKAGQEVKLMHLEKATVGFYLLPNNNHFHNVM 334 P +L++ A D +RD AYA L ++G +V + GF F + Sbjct: 253 ----PPALIITAEHDPLRDQGEAYANKLLQSGVQVTSVEFNNVIHGFV------SFFPFI 302 Query: 335 DE 336 ++ Sbjct: 303 EQ 304 >4V2I-A nrPDB Length = 323 Score = 268 bits (686), Expect = 2e-72, Method: Composition-based stats. Identities = 69/230 (30%), Positives = 109/230 (47%), Gaps = 8/230 (3%) Query: 97 LEKPV-DGDIVPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRAPENPY 155 + +P + D +PVI++FHG + ++ +D L R L +V V+Y R+PE Y Sbjct: 67 IIRPQGNTDRLPVIVYFHGAGWVMG--DTGTHDRLVRELSVRANAALVFVDYERSPEARY 124 Query: 156 PCAYDDGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGGNIAHNVALRAGESG-IDVLGN 214 P A + + +V S + +++ I AGDS GGN+ V+L A E G D+ Sbjct: 125 PVAIEQDYAVTKYVAEHSEQLNVDPTRLAI--AGDSVGGNMTAVVSLLAQERGGPDITAQ 182 Query: 215 ILLNPMFGGNERTESEKSLDGKYFVTVRDRDWYWKAFLPEGEDREHPACNPFSPRGKSLE 274 +L P+ + S ++T DW+W +LPEG DR P P + L Sbjct: 183 VLFYPVTDADFDNGSYTEFANGPWLTKPAMDWFWNQYLPEGIDRTDPKITPIHATSEQLS 242 Query: 275 GVSFPKSLVVVAGLDLIRDWQLAYAEGLKKAGQEVKLMHLEKATVGFYLL 324 G + +LV+ A D++RD AYA L +AG +V + F +L Sbjct: 243 GQA--PALVITAENDVLRDEGEAYARKLSQAGVDVTVTRYNGTIHDFVML 290 >2C7B-A nrPDB Length = 311 Score = 254 bits (650), Expect = 3e-68, Method: Composition-based stats. Identities = 71/245 (28%), Positives = 109/245 (44%), Gaps = 19/245 (7%) Query: 95 LDLEKPVDGDIVPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRAPENP 154 + P +P +L++HGG F S + +D +CRRL L VVVSV+YR APE Sbjct: 62 ARVYFPKKAAGLPAVLYYHGGGFVFGSIET--HDHICRRLSRLSDSVVVSVDYRLAPEYK 119 Query: 155 YPCAYDDGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGGNIAHNVALRAGESGIDVL-G 213 +P A +D + AL WV R+ I +AGDS+GGN+A V++ SG ++ Sbjct: 120 FPTAVEDAYAALKWVADRADELGVDPD--RIAVAGDSAGGNLAAVVSILDRNSGEKLVKK 177 Query: 214 NILLNP---MFGGNERTESEKSLDGKYFVTVRDRDWYWKAFLPEGEDREHPACNPFSPRG 270 +L+ P M G + E + + + W+ + +L E+ +P Sbjct: 178 QVLIYPVVNMTGVPTASLVEFGVAETTSLPIELMVWFGRQYLKRPEEAYDFKASPLLA-- 235 Query: 271 KSLEGVSFPKSLVVVAGLDLIRDWQLAYAEGLKKAGQEVKLMHLEKATVGFYLLPNNNHF 330 L G P +LVV A D +RD YA +K +G + GF F Sbjct: 236 -DLGG--LPPALVVTAEYDPLRDEGELYAYKMKASGSRAVAVRFAGMVHGFV------SF 286 Query: 331 HNVMD 335 + +D Sbjct: 287 YPFVD 291 >6AAE-A nrPDB Length = 317 Score = 248 bits (632), Expect = 4e-66, Method: Composition-based stats. Identities = 63/233 (27%), Positives = 102/233 (43%), Gaps = 11/233 (4%) Query: 95 LDLEKPVDGDIVPVIL-FFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRAPEN 153 L P D D P ++ ++HGG + + ++ +D CR L C V+S+ YR APE Sbjct: 60 ARLYVPEDADERPALMVYYHGGGWVIGTLDT--HDGTCRALAQKSGCAVLSIAYRLAPEY 117 Query: 154 PYPCAYDDGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGGNIAHNVALRAGESGIDVLG 213 YP +D + AL W + + + GDS+GGN+A VA+ A + L Sbjct: 118 RYPAPAEDCYDALVWAKQNAATLGVDGD--RLAVGGDSAGGNLAAAVAIMARDRNGPALR 175 Query: 214 NILLNPMFGGNERTESEKSLDGK--YFVTVRDRDWYWKAFLPEGEDREHPACNPFSPRGK 271 + LL N+ T + + +G Y+++ W+W +L + P + Sbjct: 176 HQLLIYPVTDNDFTLASYAENGGGEYYLSTDGMRWFWGHYLGDTAAENAPLAAVLNV--A 233 Query: 272 SLEGVSFPKSLVVVAGLDLIRDWQLAYAEGLKKAGQEVKLMHLEKATVGFYLL 324 L G + V+ A D +RD +AYA+ L AG V GF+ + Sbjct: 234 DLSG--LAPATVITAEYDPLRDEGIAYAKKLDAAGVPVDAATAPGMIHGFFSM 284 >5L2P-A nrPDB Length = 306 Score = 246 bits (627), Expect = 1e-65, Method: Composition-based stats. Identities = 59/239 (24%), Positives = 106/239 (44%), Gaps = 9/239 (3%) Query: 97 LEKPVDGDIVPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRAPENPYP 156 + P+ +++ FHGG++ S + D + R L C+C V+SV+YR APE +P Sbjct: 66 IYSPIKRTNNGLVMHFHGGAWILGSIETE--DAISRILSNSCECTVISVDYRLAPEYKFP 123 Query: 157 CAYDDGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGGNIAHNVALRAGESGIDVLGNIL 216 A D + A+ W + K+ F G S+GGN+ +L A ++ + + + Sbjct: 124 TAVYDCFNAIVWARDNAGELGIDKDKIATF--GISAGGNLVAATSLLARDNKLKLTAQVP 181 Query: 217 LNPMFGGNERTESEKSLDGKYFVTVR-DRDWYWKAFLPEGEDREHPACNPFSPRGKSLEG 275 + P + ++S YF+ + D+ K ++ + +D +P +P S Sbjct: 182 VVPFVYLDLASKSMNRYRKGYFLDINLPVDYGVKMYIRDEKDLYNPLFSPLIAEDLS--- 238 Query: 276 VSFPKSLVVVAGLDLIRDWQLAYAEGLKKAGQEVKLMHLEKATVGFYLLPNNNHFHNVM 334 + P+++VV A D +RD AYA L ++G + F P + VM Sbjct: 239 -NLPQAIVVTAEYDPLRDQGEAYAYRLMESGVPTLSFRVNGNVHAFLGSPRTSRQVTVM 296 >3WJ2-A nrPDB Length = 308 Score = 242 bits (618), Expect = 1e-64, Method: Composition-based stats. Identities = 49/220 (22%), Positives = 97/220 (44%), Gaps = 10/220 (4%) Query: 102 DGDIVPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRAPENPYPCAYDD 161 D + IL++HGG F + + YD CR L ++S+ YR APE+ +P A++D Sbjct: 72 DNNAKSAILYYHGGGFLFGNIET--YDNYCRFLAKESGVKIISIEYRLAPEHKFPDAFND 129 Query: 162 GWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGGNIAHNVALRAGESGIDVLG-NILLNPM 220 + + +++ + + I +AGDS+G N+A + L+ + ++ +L P Sbjct: 130 AYDSFHYIAKKKKDFGIEG---RIGVAGDSAGANLAAALCLKCRDGKTEMPAVQVLFYPS 186 Query: 221 FGGNERTESEKSLDGKYFVTVRDRDWYWKAFLPEGEDREHPACNPFSPRGKSLEGVSFPK 280 + + S Y +T + ++ + +D +P +P S + P Sbjct: 187 LAPDNFSRSFIEYSDNYVLTGKMIRYFGNMYSKNMQDLINPYFSPLVADDFS----NLPP 242 Query: 281 SLVVVAGLDLIRDWQLAYAEGLKKAGQEVKLMHLEKATVG 320 +++V D +RD + Y + L++AG + G Sbjct: 243 AIMVTNEYDPLRDPEETYVKKLREAGVRAVGIRGIGMIHG 282 >4WY5-A nrPDB Length = 332 Score = 236 bits (603), Expect = 8e-63, Method: Composition-based stats. Identities = 66/246 (26%), Positives = 112/246 (45%), Gaps = 13/246 (5%) Query: 87 DQEQPPSILDLEKP--VDGDIVPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVS 144 + + L + +P + I+PV++F HGG F S + I R L V V Sbjct: 59 ESDGKTLKLTIVRPPGTEDQILPVLIFLHGGGFVFGSKYTHIKP--VRDLTVKANVVTVF 116 Query: 145 VNYRRAPENPYPCAYDDGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGGNIAHNVALRA 204 V+Y +PE +P A ++ + A+ WV R S + + +AGDS+G ++ V++ A Sbjct: 117 VDYSLSPEAKFPTAIEEIYAAILWV--RENASSLNINAEALAVAGDSAGATLSAAVSIYA 174 Query: 205 GESGID--VLGNILLNPMFG-GNERTESEKSLD-GKYFVTVRDRDWYWKAFLPEGEDREH 260 E G+ + +L+ P + + ES K G Y ++ D ++ A+LP + Sbjct: 175 KEKGLSAAIKTQVLIYPATAVSHAKYESYKLFGNGDYILSAEDLKFFSNAYLPAPASELN 234 Query: 261 PACNPFS-PRGKSLEGVSFPKSLVVVAGLDLIRDWQLAYAEGLKKAGQEVKLMHLEKATV 319 LEG P +L+ A D++RD YA+ L +AG +V + + A Sbjct: 235 DKLATLELATKADLEG--LPPALLFTAESDVLRDEGEKYAQQLAEAGVDVAAVRVLGAVH 292 Query: 320 GFYLLP 325 GF +P Sbjct: 293 GFITVP 298 >2O7R-A nrPDB Length = 338 Score = 217 bits (552), Expect = 7e-57, Method: Composition-based stats. Identities = 78/226 (34%), Positives = 112/226 (49%), Gaps = 14/226 (6%) Query: 106 VPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRAPENPYPCAYDDGWIA 165 +P++++FHGG F SA S I+ C + V+ SV+YR APE+ P AYDD A Sbjct: 83 LPLVVYFHGGGFILFSAASTIFHDFCCEMAVHAGVVIASVDYRLAPEHRLPAAYDDAMEA 142 Query: 166 LNWVNS--RSWLKSKKDSKVHIFLAGDSSGGNIAHNVALRAGESG-----IDVLGNILLN 218 L W+ WL + D + F+ G+S+GGNIA++ LRA + + G +L Sbjct: 143 LQWIKDSRDEWLTNFADFS-NCFIMGESAGGNIAYHAGLRAAAVADELLPLKIKGLVLDE 201 Query: 219 PMFGGNERTESEKSLDGKYFVTVRDRDWYWKAFLPEGEDREHPACNPFSPRGKSLEGVSF 278 P FGG++RT SE L + D W+ LP G DR+H CNP + + L Sbjct: 202 PGFGGSKRTGSELRLANDSRLPTFVLDLIWELSLPMGADRDHEYCNP-TAESEPLYSFDK 260 Query: 279 PKSL---VVVAGL--DLIRDWQLAYAEGLKKAGQEVKLMHLEKATV 319 +SL V+V G D + D Q+ AE L+K G +V Sbjct: 261 IRSLGWRVMVVGCHGDPMIDRQMELAERLEKKGVDVVAQFDVGGYH 306 >3GA7-A nrPDB Length = 326 Score = 196 bits (498), Expect = 1e-50, Method: Composition-based stats. Identities = 52/218 (23%), Positives = 86/218 (39%), Gaps = 11/218 (5%) Query: 108 VILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRAPENPYPCAYDDGWIALN 167 + + HGG F + ++ +D + R L C V+ ++Y +P+ YP A ++ + Sbjct: 89 TLYYLHGGGFILGNLDT--HDRIMRLLARYTGCTVIGIDYSLSPQARYPQAIEETVAVCS 146 Query: 168 WVNSRSWLKSKKDSKVHIFLAGDSSGGNIAHNVALRAGESGIDV--LGNILLNPMFGGNE 225 + + + S K I AGDS+G +A AL + I + ILL G + Sbjct: 147 YFSQHADEYSLNVEK--IGFAGDSAGAMLALASALWLRDKHIRCGNVIAILLWYGLYGLQ 204 Query: 226 RTESEKSLDGKY-FVTVRDRDWYWKAFLPEGEDREHPACNPFSPRGKSLEGVSFPKSLVV 284 + S + G + +T D D Y KA+L EDRE P F+ P + Sbjct: 205 DSVSRRLFGGAWDGLTREDLDMYEKAYLRNDEDRESPWYCLFNNDLTR----DVPPCFIA 260 Query: 285 VAGLDLIRDWQLAYAEGLKKAGQEVKLMHLEKATVGFY 322 A D + D + L+ Q + F Sbjct: 261 SAEFDPLIDDSRLLHQTLQAHQQPCEYKMYPGTLHAFL 298 >4KRY-A nrPDB Length = 333 Score = 195 bits (496), Expect = 2e-50, Method: Composition-based stats. Identities = 51/220 (23%), Positives = 89/220 (40%), Gaps = 12/220 (5%) Query: 107 PVILFF-HGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRAPENPYPCAYDDGWIA 165 P LF+ HGG F + ++ +D + R L +C V+ ++Y +PE +P A ++ A Sbjct: 98 PATLFYLHGGGFILGNLDT--HDRIMRLLASYSQCTVIGIDYTLSPEARFPQAIEEIVAA 155 Query: 166 LNWVNSRSWLKSKKDSKVHIFLAGDSSGGNIAHNVALRAGESGIDV--LGNILLNPMFGG 223 + + ++ + + I AGDS+G +A AL + ID + +LL G Sbjct: 156 CCYFHQQAE--DYQINMSRIGFAGDSAGAMLALASALWLRDKQIDCGKVAGVLLWYGLYG 213 Query: 224 NERTESEKSLDGKY-FVTVRDRDWYWKAFLPEGEDREHPACNPFSPRGKSLEGVSFPKSL 282 + + + L G + +T +D Y +A+L DRE P F+ P Sbjct: 214 LRDSVTRRLLGGVWDGLTQQDLQMYEEAYLSNDADRESPYYCLFNNDLTR----EVPPCF 269 Query: 283 VVVAGLDLIRDWQLAYAEGLKKAGQEVKLMHLEKATVGFY 322 + A D + D + L Q + F Sbjct: 270 IAGAEFDPLLDDSRLLYQTLAAHQQPCEFKLYPGTLHAFL 309 >5AOA-A nrPDB Length = 286 Score = 81.6 bits (200), Expect = 5e-16, Method: Composition-based stats. Identities = 62/284 (21%), Positives = 102/284 (35%), Gaps = 42/284 (14%) Query: 75 NLLSRVYRPAYADQEQPPSILDLEKPVD---GDIVPVILFFHGGSFAHSSANSAIYDTLC 131 +VY+ + L + KP D D I+FF GG + S + A + C Sbjct: 14 GAEVKVYKKV----DNVDLKLYIYKPADWKPADRRSAIVFFFGGGW--QSGSPAQFRPQC 67 Query: 132 RRLVGLCKCVVVSVNYRRAPENPYPCA--YDDGWIALNWVNSRSWLKSKKDSKVHIFLAG 189 G V ++ +YR + A D A+ WV + K I +G Sbjct: 68 EYFAGR-GMVAMAADYRVGSRHNVKVADCVADAKSAIRWVRQHAAELGVDPQK--IVASG 124 Query: 190 DSSGGNIAHNVA----LRAGESGIDVLGN----ILLNPMFGGNERTESEKSLDGKYFVTV 241 S+GG++A L A E + IL NP+ + K V Sbjct: 125 GSAGGHLAACTVMVPDLEAPEEDHTISSQANAAILFNPVLILS-------REGLKDHVPR 177 Query: 242 RDRDWYWKAFLPEGEDREHPACNPFSPRGKSLEGVSFPKSLVV--VAGLDLIRDWQLAYA 299 +D W+ L E E A +P+ L P ++ A + + +A Sbjct: 178 QD----WEERLRERLGTEPKAVSPYHHIRAGL-----PPMIIFHGTADNTVPFETIRLFA 228 Query: 300 EGLKKAGQEVKLMHLEKATVGFYLLPNNNH--FHNVMDEISAFV 341 E +KKAG +L+ E A GF+ ++ + ++ F+ Sbjct: 229 EAMKKAGNRCELVPFEGAAHGFFNFGRGDNLAYQKTLELADEFL 272 >1C7J-A nrPDB Length = 489 Score = 62.8 bits (151), Expect = 2e-10, Method: Composition-based stats. Identities = 29/118 (24%), Positives = 49/118 (41%), Gaps = 15/118 (12%) Query: 103 GDIVPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRAP-----ENPYPC 157 +PV+++ HGG+F + + +YD +L + +VV++NYR P + + Sbjct: 94 SQNLPVMVWIHGGAFYLGAGSEPLYDGS--KLAAQGEVIVVTLNYRLGPFGFMHLSSFDE 151 Query: 158 AYDDGW------IALNWVNSRSWLKSKKDSKVHIFLAGDSSGGNIAHNVALRAGESGI 209 AY D AL WV V +F G+S+GG + G+ Sbjct: 152 AYSDNLGLLDQAAALKWVRENISAFGGDPDNVTVF--GESAGGMSIAALLAMPAAKGL 207 >1MX5-A nrPDB Length = 548 Score = 60.5 bits (145), Expect = 1e-09, Method: Composition-based stats. Identities = 31/120 (25%), Positives = 48/120 (40%), Gaps = 18/120 (15%) Query: 95 LDLEKPVD---GDIVPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRAP 151 L++ P D + +PV+++ HGG +A++ YD L L VVV++ YR Sbjct: 101 LNIYTPADLTKKNRLPVMVWIHGGGLMVGAAST--YDGL--ALAAHENVVVVTIQYRLGI 156 Query: 152 ENPYPCAYD---------DGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGGNIAHNVAL 202 + + D AL WV V IF G+S+GG + L Sbjct: 157 WGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIF--GESAGGESVSVLVL 214 >5FV4-A nrPDB Length = 544 Score = 58.9 bits (141), Expect = 3e-09, Method: Composition-based stats. Identities = 31/120 (25%), Positives = 47/120 (39%), Gaps = 18/120 (15%) Query: 95 LDLEKPVD---GDIVPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRAP 151 L++ P D +PV+++ HGG A++ YD L L VVV++ YR Sbjct: 102 LNIYTPADLTKRGRLPVMVWIHGGGLVVGGAST--YDGL--ALAAHENVVVVAIQYRLGI 157 Query: 152 ENPYPCAYD---------DGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGGNIAHNVAL 202 + + D AL+WV V IF G+S+GG + L Sbjct: 158 WGFFSTGDEHSRGNWGHLDQVAALHWVQENIANFGGDPGSVTIF--GESAGGESVSVLVL 215 >1K4Y-A nrPDB Length = 534 Score = 57.0 bits (136), Expect = 1e-08, Method: Composition-based stats. Identities = 30/112 (26%), Positives = 44/112 (39%), Gaps = 18/112 (16%) Query: 95 LDLEKPVD---GDIVPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRAP 151 L++ P D +PV+++ HGG A++ YD L L VVV++ YR Sbjct: 97 LNIYTPADLTKRGRLPVMVWIHGGGLMVGGAST--YDGL--ALSAHENVVVVTIQYRLGI 152 Query: 152 ENPYPCAYD---------DGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGG 194 + + D AL WV V IF G+S+GG Sbjct: 153 WGFFSTGDEHSRGNWGHLDQVAALRWVQDNIANFGGDPGSVTIF--GESAGG 202 >1Q83-A nrPDB Length = 580 Score = 55.1 bits (131), Expect = 4e-08, Method: Composition-based stats. Identities = 29/105 (27%), Positives = 44/105 (41%), Gaps = 14/105 (13%) Query: 100 PVDGDIVPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRR---------- 149 P PV+++ +GG F +A+ +YD R L + V+VS+NYR Sbjct: 137 PRPASPTPVLIWIYGGGFYSGAASLDVYDG--RFLAQVEGAVLVSMNYRVGTFGFLALPG 194 Query: 150 APENPYPCAYDDGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGG 194 + E P D +AL WV V +F G+S+G Sbjct: 195 SREAPGNVGLLDQRLALQWVQENIAAFGGDPMSVTLF--GESAGA 237 >4Q3K-A nrPDB Length = 260 Score = 54.7 bits (130), Expect = 5e-08, Method: Composition-based stats. Identities = 42/219 (19%), Positives = 66/219 (30%), Gaps = 47/219 (21%) Query: 106 VPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRAPENPYPCAYDDGWIA 165 P +L F GG + S + L V+ Y +P D A Sbjct: 54 RPAMLIFPGGGYQFCS-DREAEPIALSYLAKGYNAFVL--RYSVKEHAVFPRPLIDAEDA 110 Query: 166 LNWVNSRSWLKSKKDSKVHIFLAGDSSGGNIAHNVALRAGESGIDVLGNILLNPMFGGNE 225 L+++ + K I + G S+GG++A A E + +L P +E Sbjct: 111 LSYLKDNAHALHINPDK--IAVIGFSAGGHLA---TTLATEGKVRPNAVVLGYPALIRHE 165 Query: 226 RTESEKSLDGKYFVTVRDRDWYWKAFLPEGE-DREHPACNPFSPRGKSLEGVSFPKSLVV 284 + YW P + D++ P F L +S P +V Sbjct: 166 K--------------------YWN--FPTPKVDQQTPEMFVFHTFEDDLVPLSHPLYIV- 202 Query: 285 VAGLDLIRDWQLAYAEGLKKAGQEVKLMHLEKATVGFYL 323 E L KA V+ + G L Sbjct: 203 ---------------EELSKANIPVEFHLFKSGVHGLSL 226 >5YDJ-A nrPDB Length = 737 Score = 53.5 bits (127), Expect = 1e-07, Method: Composition-based stats. Identities = 31/105 (29%), Positives = 44/105 (41%), Gaps = 14/105 (13%) Query: 99 KPVDGDIVPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRA-------- 150 +P + V+L+ GG F +A +YD R L +VVS+ YR A Sbjct: 264 RPRPKNA-AVMLWIFGGGFYSGTATLDVYDH--RALASEENVIVVSLQYRVASLGFLFLG 320 Query: 151 -PENPYPCAYDDGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGG 194 PE P D +AL WV S+V +F G+S+G Sbjct: 321 TPEAPGNAGLFDQNLALRWVRDNIHRFGGDPSRVTLF--GESAGA 363 >5YDI-A nrPDB Length = 553 Score = 53.1 bits (126), Expect = 2e-07, Method: Composition-based stats. Identities = 31/105 (29%), Positives = 44/105 (41%), Gaps = 14/105 (13%) Query: 99 KPVDGDIVPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRA-------- 150 +P + V+L+ GG F +A +YD R L +VVS+ YR A Sbjct: 103 RPRPKNA-AVMLWIFGGGFYSGTATLDVYDH--RALASEENVIVVSLQYRVASLGFLFLG 159 Query: 151 -PENPYPCAYDDGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGG 194 PE P D +AL WV S+V +F G+S+G Sbjct: 160 TPEAPGNAGLFDQNLALRWVRDNIHRFGGDPSRVTLF--GESAGA 202 >5THM-A nrPDB Length = 533 Score = 52.7 bits (125), Expect = 2e-07, Method: Composition-based stats. Identities = 31/127 (24%), Positives = 52/127 (40%), Gaps = 17/127 (13%) Query: 88 QEQPPSILDLEKPVDGDI--VPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSV 145 E+ + + KP + PV+ HGG+F +A ++ + R K ++V + Sbjct: 90 GEEDCLTVSVYKPKNSKRNSFPVVAHIHGGAFMFGAAWQNGHENVMRE----GKFILVKI 145 Query: 146 NYRRAP-------ENPYPCAY--DDGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGGNI 196 +YR P + P Y D +AL W+ + S ++ L G S+GG Sbjct: 146 SYRLGPLGFLSTGDRDLPGNYGLKDQRLALKWIKQN--IASFGGEPQNVLLVGHSAGGAS 203 Query: 197 AHNVALR 203 H LR Sbjct: 204 VHLQMLR 210 >2X8B-A nrPDB Length = 583 Score = 52.7 bits (125), Expect = 2e-07, Method: Composition-based stats. Identities = 29/105 (27%), Positives = 46/105 (43%), Gaps = 14/105 (13%) Query: 100 PVDGDIVPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRR---------- 149 P PV+++ +GG F +++ +YD R LV + V+VS+NYR Sbjct: 106 PRPTSPTPVLVWIYGGGFYSGASSLDVYDG--RFLVQAERTVLVSMNYRVGAFGFLALPG 163 Query: 150 APENPYPCAYDDGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGG 194 + E P D +AL WV + V +F G+S+G Sbjct: 164 SREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLF--GESAGA 206 >6EMI-A nrPDB Length = 532 Score = 52.0 bits (123), Expect = 3e-07, Method: Composition-based stats. Identities = 29/105 (27%), Positives = 50/105 (47%), Gaps = 17/105 (16%) Query: 108 VILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRA----------PENPYPC 157 V+++ +GG F +++ +YD + L + + +VVS+NYR PE P Sbjct: 112 VMVWIYGGGFQTGTSSLPVYDG--KFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNM 169 Query: 158 AYDDGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGGNIAHNVAL 202 D +AL WV ++V +F G+S+G A +V+L Sbjct: 170 GLFDQQLALKWVQDNIAAFGGDPNRVTLF--GESAG---AASVSL 209 >4QWW-A nrPDB Length = 542 Score = 52.0 bits (123), Expect = 3e-07, Method: Composition-based stats. Identities = 28/106 (26%), Positives = 47/106 (44%), Gaps = 17/106 (16%) Query: 99 KPVDGDIVPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRR--------- 149 +P D PV+++ +GG F +A+ +YD R L ++VS++YR Sbjct: 105 RPKDA---PVLVWIYGGGFYSGAASLDVYDG--RFLTYTQNVILVSLSYRVGAFGFLGLP 159 Query: 150 -APENPYPCAYDDGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGG 194 +PE P D +AL W+ + V +F G+S+G Sbjct: 160 GSPEAPGNMGLLDQRLALQWIQNNIHPFGGNPRAVTVF--GESAGA 203 >1THG-A nrPDB Length = 544 Score = 51.6 bits (122), Expect = 5e-07, Method: Composition-based stats. Identities = 28/120 (23%), Positives = 51/120 (42%), Gaps = 17/120 (14%) Query: 95 LDLEKPVDGDI---VPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVV-VSVNYRRA 150 L++ +P +PV+++ +GG+F + S+ + ++ + + + + VV VS+NYR Sbjct: 108 LNVFRPAGTKPDAKLPVMVWIYGGAFVYGSSAAYPGNSYVKESINMGQPVVFVSINYRTG 167 Query: 151 P-----------ENPYPCAYDDGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGGNIAHN 199 P E D L WV+ KV IF G+S+G + Sbjct: 168 PFGFLGGDAITAEGNTNAGLHDQRKGLEWVSDNIANFGGDPDKVMIF--GESAGAMSVAH 225 >6QAA-A nrPDB Length = 557 Score = 51.2 bits (121), Expect = 7e-07, Method: Composition-based stats. Identities = 34/140 (24%), Positives = 55/140 (39%), Gaps = 19/140 (13%) Query: 108 VILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRA----------PENPYPC 157 V+++ +GG F +++ +YD + L + + +VVS+NYR PE P Sbjct: 137 VLIWIYGGGFQTGTSSLHVYDG--KFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNM 194 Query: 158 AYDDGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGGNIAHNVA--LRAGESGIDVLGNI 215 D +AL WV V +F G+S+G A +V+ L + S I Sbjct: 195 GLFDQQLALQWVQKNIAAFGGNPKSVTLF--GESAG---AASVSLHLLSPGSHSLFTRAI 249 Query: 216 LLNPMFGGNERTESEKSLDG 235 L + F S Sbjct: 250 LQSGSFNAPWAVTSLYEARN 269 >3BIX-A nrPDB Length = 574 Score = 50.1 bits (118), Expect = 2e-06, Method: Composition-based stats. Identities = 28/123 (22%), Positives = 47/123 (38%), Gaps = 21/123 (17%) Query: 87 DQEQPPSILDLEKPVDGD------IVPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKC 140 DQ + L++ P + D PV+++ HGGS+ + N +YD L Sbjct: 106 DQSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIHGGSYMEGTGN--LYDGSV--LASYGNV 161 Query: 141 VVVSVNYRRA---------PENPYPCAYDDGWIALNWVNSRSWLKSKKDSKVHIFLAGDS 191 +V++VNYR D AL W + ++ +F +G Sbjct: 162 IVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSG-- 219 Query: 192 SGG 194 +GG Sbjct: 220 AGG 222 >2WQZ-A nrPDB Length = 588 Score = 48.5 bits (114), Expect = 4e-06, Method: Composition-based stats. Identities = 28/131 (21%), Positives = 47/131 (35%), Gaps = 21/131 (16%) Query: 87 DQEQPPSILDLEKPVDGDI------VPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKC 140 DQ + L++ P + DI PV+++ HGGS+ + N L Sbjct: 110 DQNEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGNMIDGS----ILASYGNV 165 Query: 141 VVVSVNYRRA---------PENPYPCAYDDGWIALNWVNSRSWLKSKKDSKVHIFLAGDS 191 +V+++NYR D AL W+ +V IF +G Sbjct: 166 IVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSG-- 223 Query: 192 SGGNIAHNVAL 202 +G + + L Sbjct: 224 AGASCVSLLTL 234 >6H18-A nrPDB Length = 547 Score = 47.7 bits (112), Expect = 7e-06, Method: Composition-based stats. Identities = 26/104 (25%), Positives = 44/104 (42%), Gaps = 19/104 (18%) Query: 106 VPVILFFHGGSFAHSSA------NSAIYDTLCRRLVGLCKCVVVSVNYRRAP-------E 152 +PV+++ +GG+F S N+ +YD + +VV+ NYR P + Sbjct: 112 LPVMIWIYGGAFLMGSGHGANFLNNYLYDG--EEIATRGNVIVVTFNYRVGPLGFLSTGD 169 Query: 153 NPYPCAY--DDGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGG 194 P Y D +A+ WV + +F G+S+GG Sbjct: 170 ANLPGNYGLRDQHMAIAWVKRNIAAFGGDPDNITLF--GESAGG 211 >1VKH-A nrPDB Length = 273 Score = 45.8 bits (107), Expect = 3e-05, Method: Composition-based stats. Identities = 25/178 (14%), Positives = 54/178 (30%), Gaps = 21/178 (11%) Query: 101 VDGDIVPVILFFHGGSFAHSSANSAIYD-----TLCRRLVGLCKCVVVSVNYRRAPENPY 155 + + +++ HGG++ + + D + + S+ YR +PE Sbjct: 36 ISQNTREAVIYIHGGAW--NDPENTPNDFNQLANTIKSMDTESTVCQYSIEYRLSPEITN 93 Query: 156 PCAYDDGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGGNIAHNVALRAGESGIDVLGNI 215 P D + + L + + G S G + + + Sbjct: 94 PRNLYDAVSNITRLVKEKGLTNIN-------MVGHSVGATFIWQILAALKDPQEKMSEAQ 146 Query: 216 LLNPMFGGNERTESEKSLDGKYFVTVRDRDW-----YWKAFLPEGEDREHPACNPFSP 268 L M G + + LDG Y + ++ + + P+G + P Sbjct: 147 L--QMLGLLQIVKRVFLLDGIYSLKELLIEYPEYDCFTRLAFPDGIQMYEEEPSRVMP 202 >1QON-A nrPDB Length = 585 Score = 45.4 bits (106), Expect = 4e-05, Method: Composition-based stats. Identities = 24/107 (22%), Positives = 44/107 (41%), Gaps = 20/107 (18%) Query: 103 GDIVPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYR--------RAPENP 154 + +P++++ +GG F SA IY+ + + +V S YR APE P Sbjct: 138 TNGLPILIWIYGGGFMTGSATLDIYNA--DIMAAVGNVIVASFQYRVGAFGFLHLAPEMP 195 Query: 155 YPCAYD--------DGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSG 193 A + D +A+ W+ + + +F G+S+G Sbjct: 196 SEFAEEAPGNVGLWDQALAIRWLKDNAHAFGGNPEWMTLF--GESAG 240 >1AKN-A nrPDB Length = 579 Score = 43.9 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 24/111 (21%), Positives = 46/111 (41%), Gaps = 19/111 (17%) Query: 99 KPVDGDIVPVILFFHGGSFAHSS------ANSAIYDTLCRRLVGLCKCVVVSVNYRRAP- 151 + +PV+++ +GG+F + ++ +YD + +VV+ NYR P Sbjct: 91 RKEVSHDLPVMIWIYGGAFLMGASQGANFLSNYLYDG--EEIATRGNVIVVTFNYRVGPL 148 Query: 152 ------ENPYPCAYD--DGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGG 194 ++ P Y D +A+ WV + +F G+S+GG Sbjct: 149 GFLSTGDSNLPGNYGLWDQHMAIAWVKRNIEAFGGDPDNITLF--GESAGG 197 >2W6C-X nrPDB Length = 586 Score = 43.5 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 14/97 (14%) Query: 108 VILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRR----------APENPYPC 157 V+++ +GG F S+ +Y+ + L + V+VS++YR + E P Sbjct: 132 VMVWIYGGGFYSGSSTLDVYNG--KYLAYTEEVVLVSLSYRVGAFGFLALHGSQEAPGNV 189 Query: 158 AYDDGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGG 194 D +AL WV+ V IF G+S+GG Sbjct: 190 GLLDQRMALQWVHDNIQFFGGDPKTVTIF--GESAGG 224 >5V5V-A nrPDB Length = 582 Score = 43.1 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 23/101 (22%), Positives = 37/101 (36%), Gaps = 13/101 (12%) Query: 101 VDGDIVPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRA---------P 151 D PV+LF HGGS+ + N ++D L +V ++NYR Sbjct: 132 RDSGKKPVMLFLHGGSYMEGTGN--MFDGSV--LAAYGNVIVATLNYRLGVLGFLSTGDQ 187 Query: 152 ENPYPCAYDDGWIALNWVNSRSWLKSKKDSKVHIFLAGDSS 192 D AL W++ ++ IF +G + Sbjct: 188 AAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSGAGA 228 >1GZ7-A nrPDB Length = 534 Score = 39.7 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 33/142 (23%), Positives = 56/142 (39%), Gaps = 16/142 (11%) Query: 76 LLSRVYRPAYADQEQPPSILDLEKP--VDGDIVPVILFFHGGSFAHSSANSAIYDTLCRR 133 L S++++ + E +I + P +PV+L+ GG F ++ D + + Sbjct: 82 LQSKIFQVVLPNDEDCLTINVIRPPGTRASAGLPVMLWIFGGGFELGGSSLFPGDQMVAK 141 Query: 134 LVGLCKCVV-VSVNYRRAP-----------ENPYPCAYDDGWIALNWVNSRSWLKSKKDS 181 V + K V+ VS+NYR A E D +A+ WV S Sbjct: 142 SVLMGKPVIHVSMNYRVASWGFLAGPDIQNEGSGNAGLHDQRLAMQWVADNIAGFGGDPS 201 Query: 182 KVHIFLAGDSSGGNIAHNVALR 203 KV I+ G+S+G + Sbjct: 202 KVTIY--GESAGSMSTFVHLVW 221 >1LLF-A nrPDB Length = 534 Score = 38.5 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 39/183 (21%), Positives = 66/183 (36%), Gaps = 38/183 (20%) Query: 35 RRPDGTFNRHLAEYLDRKVTANANPVDGVFSFDVLIDRRINLLSRVYRPAYADQEQPPSI 94 + P+GTF +L + + D++ + S+V++ E +I Sbjct: 63 QNPEGTFEENLGK----------------TALDLV------MQSKVFQAVLPQSEDCLTI 100 Query: 95 LDLEKP--VDGDIVPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVV-VSVNYRRA- 150 + P G +PV+L+ GG F S + + V + K ++ V+VNYR A Sbjct: 101 NVVRPPGTKAGANLPVMLWIFGGGFEIGSPTIFPPAQMVTKSVLMGKPIIHVAVNYRVAS 160 Query: 151 ----------PENPYPCAYDDGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGGNIAHNV 200 E D + + WV SKV IF G+S+G Sbjct: 161 WGFLAGDDIKAEGSGNAGLKDQRLGMQWVADNIAGFGGDPSKVTIF--GESAGSMSVLCH 218 Query: 201 ALR 203 + Sbjct: 219 LIW 221 >3RAR-A nrPDB Length = 534 Score = 38.5 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 29/134 (21%), Positives = 49/134 (36%), Gaps = 16/134 (11%) Query: 76 LLSRVYRPAYADQEQPPSILDLEKP--VDGDIVPVILFFHGGSFAHSSANS-AIYDTLCR 132 + S+V+ E +I + P G +PV+L+ GG F ++ + + Sbjct: 82 MQSKVFEAVSPSSEDCLTINVVRPPGTKAGANLPVMLWIFGGGFEVGGTSTFPPAQMITK 141 Query: 133 RLVGLCKCVVVSVNYRRA-----------PENPYPCAYDDGWIALNWVNSRSWLKSKKDS 181 + + VSVNYR + E D + + WV + Sbjct: 142 SIAMGKPIIHVSVNYRVSSWGFLAGDEIKAEGSANAGLKDQRLGMQWVADNIAAFGGDPT 201 Query: 182 KVHIFLAGDSSGGN 195 KV IF G+S+G Sbjct: 202 KVTIF--GESAGSM 213 >4BZW-A nrPDB Length = 282 Score = 37.3 bits (85), Expect = 0.009, Method: Composition-based stats. Identities = 20/94 (21%), Positives = 38/94 (40%), Gaps = 7/94 (7%) Query: 107 PVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRR--APENPYPCAYDDGWI 164 P+++ GG F + S R + V +NY+ ++ YP A Sbjct: 35 PIMIICPGGGFTYHSGREEA-PIATRMMA--AGMHTVVLNYQLIVGDQSVYPWALQQLGA 91 Query: 165 ALNWVNSRSWLKSKKDSKVHIFLAGDSSGGNIAH 198 ++W+ +++ I LAG S+GG++ Sbjct: 92 TIDWITTQASAHHV--DCQRIILAGFSAGGHVVA 123 >5HQ3-A nrPDB Length = 548 Score = 36.6 bits (83), Expect = 0.015, Method: Composition-based stats. Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 14/105 (13%) Query: 100 PVDGDIVPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRR---------- 149 P + PV+++ +GG F S++ +YD R LV + V+VS+NYR Sbjct: 107 PRPKNPAPVMVWIYGGGFYSGSSSLDVYDG--RFLVRTERVVLVSMNYRVGAFGFLALPG 164 Query: 150 APENPYPCAYDDGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGG 194 + E P D +AL WV + V +F G+S+G Sbjct: 165 SREAPGNVGLLDQRLALQWVQENIAAFGGDPTSVTLF--GESAGA 207 >5L8S-A nrPDB Length = 604 Score = 35.0 bits (79), Expect = 0.047, Method: Composition-based stats. Identities = 35/176 (19%), Positives = 64/176 (36%), Gaps = 23/176 (13%) Query: 161 DGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGGNIAHNVALRAGESGIDVLGNILLNPM 220 D + W+ S + +FL G S GG +A L D ++ Sbjct: 433 DCIAGIEWLFE-----SGFTDRNKLFLVGGSYGGYMA----LLLHGRHSDYFRAVVDI-- 481 Query: 221 FGGNERTESEKSLDGKYFVTVRDRDWYWKAFLPEGEDREHPACNPFSPRGKSLEGVSFPK 280 FG ++ S+ + + W PE + +P + L+G+ P Sbjct: 482 FGPSDLFTFINSVPPHWKPIME--RWLGD---PERDKERFIKDSPVTY----LDGMVKP- 531 Query: 281 SLVVVAGLDL--IRDWQLAYAEGLKKAGQEVKLMHLEKATVGFYLLPNNNHFHNVM 334 LV+ D +++ LK+ G++V+ + LE GF N +++M Sbjct: 532 MLVIQGAKDPRVVKEESDQIVAKLKEKGRDVEYLVLEDEGHGFSKKENEIKVYSLM 587 >3HXK-A nrPDB Length = 276 Score = 32.3 bits (72), Expect = 0.33, Method: Composition-based stats. Identities = 28/136 (20%), Positives = 49/136 (36%), Gaps = 15/136 (11%) Query: 97 LEKPVDGD--IVPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKC-VVVSVNYRR---A 150 L+ P + P I+ GG + H S + D L L L + V+ +NY Sbjct: 32 LQNPRQNENYTFPAIIICPGGGYQHISQRES--DPL--ALAFLAQGYQVLLLNYTVMNKG 87 Query: 151 PENPY-PCAYDDGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGGNIAHNVALRAGESGI 209 + ++ + ++ K + + +FL G S+GG++A E Sbjct: 88 TNYNFLSQNLEEVQAVFSLIHQNH--KEWQINPEQVFLLGCSAGGHLAAWYG--NSEQIH 143 Query: 210 DVLGNILLNPMFGGNE 225 G IL P+ Sbjct: 144 RPKGVILCYPVTSFTF 159 >3C5W-P nrPDB Length = 310 Score = 30.8 bits (68), Expect = 0.98, Method: Composition-based stats. Identities = 25/115 (21%), Positives = 41/115 (35%), Gaps = 5/115 (4%) Query: 87 DQEQPPSILDLEKPVDGDIVPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVN 146 + E G PV+L HGG HS+ + A++ ++ +C +V+++ Sbjct: 23 EVENETGKDTFRVYKSGSEGPVLLLLHGGG--HSALSWAVFTA---AIISRVQCRIVALD 77 Query: 147 YRRAPENPYPCAYDDGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGGNIAHNVA 201 R E D + D I L G + GG IA + A Sbjct: 78 LRSHGETKVKNPEDLSAETMAKDVGNVVEAMYGDLPPPIMLIGHAMGGAIAVHTA 132 >6FVJ-A nrPDB Length = 261 Score = 30.0 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 35/189 (18%), Positives = 56/189 (29%), Gaps = 34/189 (17%) Query: 104 DIVPVILFF-HGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYR-------RAPENPY 155 P + F H G + Y R ++V Y P Sbjct: 26 QAAPTLYIFPHAGG------TAKDYVAFSREFS--ADVKRIAVQYPGQHDRSGLPPLESI 77 Query: 156 PCAYDDGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGGNIAHNVALRAGESGIDVLGNI 215 P D+ + + ++ D V F G S GG +A VALR +G VL Sbjct: 78 PTLADEIFAMMK-------PSARIDDPVAFF--GHSMGGMLAFEVALRYQSAGHRVLAFF 128 Query: 216 LLNPMFGGNERTESEKSLDGKYFVTVRDRDWYWKAFLPEG----EDREHPACNPFSPRGK 271 + G+ R + + L D + + +D P + Sbjct: 129 VSACSAPGHIRYKQLQDLSD-----REMLDLFTRMTGMNPDFFTDDEFFVGALPTLRAVR 183 Query: 272 SLEGVSFPK 280 ++ G S P Sbjct: 184 AIAGYSCPP 192 >4HXF-B nrPDB Length = 622 Score = 30.0 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 40/236 (16%), Positives = 72/236 (30%), Gaps = 47/236 (19%) Query: 102 DGDIVPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRAPENPYPCA--- 158 +G+ PVI+F HGG Y +L+ +V VN R + A Sbjct: 374 EGEKAPVIVFVHGG----PKGMYGYYFKYEMQLMASKGYYIVYVNPRGSNGYSEDFALRV 429 Query: 159 -----YDDGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGGNIAHNVALRAGESGIDVLG 213 +D LN + + + I + G S GG + + Sbjct: 430 LERTGLEDFQDILNGI-EEFLRLEPQADRERIGITGISYGGYMTN--------------- 473 Query: 214 NILLNPMFGGNERTESEKSLDGKYFVTVRDRD----WYWKAFLPEG--EDREHPACNPFS 267 + + Y++T W+ K + + E+ + +P Sbjct: 474 ----WALTQSDLFKAGISENGISYWLTSYAFSDIGLWFDKEVIGDNPLENENYRKLSPLF 529 Query: 268 PRGKSLEGVSFPKSLVVVAGLD---LIRDWQLAYAEGLKKAGQEVKLMHLEKATVG 320 L++ + D + D L + LK G+EV + +K G Sbjct: 530 -----YAKNVKAPLLLIHSLEDYRCPL-DQSLMFYHVLKDLGKEVYIAIFKKGAHG 579 >1HP5-A nrPDB Length = 512 Score = 29.6 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 25/73 (34%), Gaps = 8/73 (10%) Query: 50 DRKVTANANPVDGVFSFDVLIDRRINLLSRVYRPAYADQEQPPSI-------LDLEKPVD 102 DRK P+D V +D R+ R + + DL +P Sbjct: 14 DRKAPVRPTPLDRVIPAPASVDPG-GAPYRITRGTHIRVDDSREARRVGDYLADLLRPAT 72 Query: 103 GDIVPVILFFHGG 115 G +PV HGG Sbjct: 73 GYRLPVTAHGHGG 85 >2ORY-A nrPDB Length = 346 Score = 29.6 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 12/43 (27%), Positives = 20/43 (46%), Gaps = 1/43 (2%) Query: 174 WLKSKKDSKVHIFLAGDSSGGNIAHNVALRAGE-SGIDVLGNI 215 K + K I + G S GG ++ +AL + G+ + NI Sbjct: 157 NEKIGPEGKAKICVTGHSKGGALSSTLALWLKDIQGVKLSQNI 199 >2EQ5-A nrPDB Length = 228 Score = 29.6 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 14/57 (24%), Positives = 22/57 (38%), Gaps = 12/57 (21%) Query: 284 VVAGLDLIRDWQ----LAYAEGLKKAGQEVKLMHLEKATVGFYLLPNNNHFHNVMDE 336 V LDL+ DW + A+ LK+ G EV + + V++E Sbjct: 148 VSNTLDLLTDWGRREVINAAKRLKEKGVEVIALGCTGM--------STIGIAPVLEE 196 >4LMA-A nrPDB Length = 326 Score = 28.1 bits (61), Expect = 5.5, Method: Composition-based stats. Identities = 13/71 (18%), Positives = 28/71 (39%), Gaps = 1/71 (1%) Query: 170 NSRSWLKSKKDSKVHIFLAGDSSGGNIAHNVALRAGESGIDVLGNILLNPMFGGNERTES 229 + ++ ++ +K L+G SSG N+ + L L +++ P FG + Sbjct: 255 DEEAFQFGRRLAKEEGLLSGISSGANLCAAIQLAQRPENEGKL-IVVIQPSFGERYLSTL 313 Query: 230 EKSLDGKYFVT 240 + +T Sbjct: 314 MFQNIEERELT 324 >5D3Z-A nrPDB Length = 269 Score = 28.1 bits (61), Expect = 5.8, Method: Composition-based stats. Identities = 10/36 (27%), Positives = 18/36 (50%), Gaps = 2/36 (5%) Query: 187 LAGDSSGGNIAHNVALRAGESGIDVLGNILL--NPM 220 +AG S+G +A+ +A + G G +L+ P Sbjct: 124 VAGHSAGALMAYALATELLDRGHPPRGVVLIDVYPP 159 >6MLK-A nrPDB Length = 300 Score = 28.1 bits (61), Expect = 5.9, Method: Composition-based stats. Identities = 10/36 (27%), Positives = 18/36 (50%), Gaps = 2/36 (5%) Query: 187 LAGDSSGGNIAHNVALRAGESGIDVLGNILL--NPM 220 +AG S+G +A+ +A + G G +L+ P Sbjct: 138 VAGHSAGALMAYALATELLDRGHPPRGVVLIDVYPP 173 >4C7D-A nrPDB Length = 494 Score = 28.1 bits (61), Expect = 6.4, Method: Composition-based stats. Identities = 19/67 (28%), Positives = 28/67 (41%), Gaps = 5/67 (7%) Query: 49 LDRKVTANANPVDGVFSFDVLIDRRINLLSRVYRPAYADQEQPPSILDLEKPVDGDIVPV 108 LDR + A A+ G + I R ++ R A + + DL +P G +PV Sbjct: 6 LDRVIPAPASVEPGGAPYR--ITRGTHIRVDDSREARRVGDY---LADLLRPATGYRLPV 60 Query: 109 ILFFHGG 115 HGG Sbjct: 61 TSHGHGG 67 >3P1V-A nrPDB Length = 407 Score = 28.1 bits (61), Expect = 6.6, Method: Composition-based stats. Identities = 18/90 (20%), Positives = 33/90 (36%), Gaps = 10/90 (11%) Query: 48 YLDRKVTANANPVDGVFSFDVLIDRRINLLSRVYRPAYADQEQPPSILDLEKPVDGDIVP 107 + D V + P+D V ++ I R+N S+ ++ PS + P+ Sbjct: 307 FYDNDVMTDTYPLD-VEPWEQNISTRVNFASKW-------KDMLPSGAPIPTPIAEKKKY 358 Query: 108 VILFFHGGSFAHSSANSAIYDTLCRRLVGL 137 + + GG ++ YD CR Sbjct: 359 PVGVYEGGGYSAKGIYRPAYD--CRMKTNE 386 >6DAO-B nrPDB Length = 331 Score = 27.7 bits (60), Expect = 6.7, Method: Composition-based stats. Identities = 10/73 (13%), Positives = 21/73 (28%), Gaps = 13/73 (17%) Query: 135 VGLCKCVVVSVNYRRAPENPYPCAYDDGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGG 194 ++ ++ + AP + DD + A ++ F SSG Sbjct: 182 AKYLGIGMLDLDLKLAPNIRFLPHEDDYYAAAR----------INPERITAFW---SSGA 228 Query: 195 NIAHNVALRAGES 207 A+ + Sbjct: 229 MCGPATAIMLRDE 241 >5LF8-A nrPDB Length = 328 Score = 27.7 bits (60), Expect = 6.9, Method: Composition-based stats. Identities = 11/29 (37%), Positives = 16/29 (55%) Query: 83 PAYADQEQPPSILDLEKPVDGDIVPVILF 111 P Q+ PPS+L +E DG P++L Sbjct: 232 PGLLPQDLPPSVLAVELEEDGRARPLVLH 260 >1XRN-A nrPDB Length = 293 Score = 27.7 bits (60), Expect = 7.2, Method: Composition-based stats. Identities = 24/125 (19%), Positives = 42/125 (33%), Gaps = 20/125 (16%) Query: 104 DIVPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRAPENPYPCAYDDGW 163 + ++ HGG S Y R + V+ + + C + Sbjct: 26 EEKAKLMTMHGG-----PGMSHDYLLSLRDMTKE-GITVLFYD-------QFGCGRSEEP 72 Query: 164 IALNW-----VNSRSWLKSKKDSKVHIFLAGDSSGGNIAHNVALRAGE--SGIDVLGNIL 216 + V L+SK +FL G S GG +A A++ + G+ V G + Sbjct: 73 DQSKFTIDYGVEEAEALRSKLFGNEKVFLMGSSYGGALALAYAVKYQDHLKGLIVSGGLS 132 Query: 217 LNPMF 221 P+ Sbjct: 133 SVPLT 137 >3JWE-A nrPDB Length = 320 Score = 27.7 bits (60), Expect = 7.3, Method: Composition-based stats. Identities = 17/61 (27%), Positives = 25/61 (40%), Gaps = 3/61 (4%) Query: 169 VNSRSWLKSKKDSKVHIFLAGDSSGGNIAHNVALRAGESGIDVLGNILLNPMFGGNERTE 228 V K + +FL G S GG IA L A E G +L++P+ N + Sbjct: 117 VLQHVDSMQKDYPGLPVFLLGHSMGGAIAI---LTAAERPGHFAGMVLISPLVLANPESA 173 Query: 229 S 229 + Sbjct: 174 T 174 >4B6G-A nrPDB Length = 283 Score = 27.7 bits (60), Expect = 7.7, Method: Composition-based stats. Identities = 24/145 (16%), Positives = 46/145 (31%), Gaps = 19/145 (13%) Query: 187 LAGDSSGGNIAHNVALRAGESGIDVLGNILLNPMFGGNERTESEKSLDGKYFVTVRDRDW 246 + G S GG+ A +ALR E V +P+ + EK+ Sbjct: 149 IMGHSMGGHGALVLALRNQERYQSVSA---FSPILSPSLVPWGEKAFTAYLGKDREK--- 202 Query: 247 YWKAFLPEGEDREHPACNPFSPRGKSLEGVSFPKSLVVVAGLDLIRDWQLAYAEGLKKAG 306 W+ + N +G ++G+ + L + + E + A Sbjct: 203 -WQQY----------DANSLIQQGYKVQGMRIDQGL--EDEFLPTQLRTEDFIETCRAAN 249 Query: 307 QEVKLMHLEKATVGFYLLPNNNHFH 331 Q V + + +Y + + H Sbjct: 250 QPVDVRFHKGYDHSYYFIASFIGEH 274 >2EBA-A nrPDB Length = 385 Score = 27.7 bits (60), Expect = 7.9, Method: Composition-based stats. Identities = 9/20 (45%), Positives = 13/20 (65%) Query: 194 GNIAHNVALRAGESGIDVLG 213 GN+AH + A + G +VLG Sbjct: 167 GNLAHLAVIWAKDEGGEVLG 186 >5HFN-A nrPDB Length = 311 Score = 27.7 bits (60), Expect = 8.3, Method: Composition-based stats. Identities = 9/30 (30%), Positives = 16/30 (53%) Query: 179 KDSKVHIFLAGDSSGGNIAHNVALRAGESG 208 + + I +AG S GG IA V+ + ++ Sbjct: 162 QVDQERIVIAGGSQGGGIALAVSALSKKAK 191 >3O4I-A nrPDB Length = 582 Score = 27.3 bits (59), Expect = 8.8, Method: Composition-based stats. Identities = 24/103 (23%), Positives = 35/103 (33%), Gaps = 22/103 (21%) Query: 107 PVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRAP----ENPY-----PC 157 P ++ HGG F + +S +DT L VV NYR + E PC Sbjct: 361 PTVVLVHGGPF---AEDSDSWDTFAASLAA-AGFHVVMPNYRGSTGYGEEWRLKIIGDPC 416 Query: 158 A--YDDGWIALNWVNSRSWLKSKKDSKVHIFLAGDSSGGNIAH 198 +D A W +++ G S GG + Sbjct: 417 GGELEDVSAAARWARESGLA-------SELYIMGYSYGGYMTL 452 >5FDF-A nrPDB Length = 337 Score = 27.3 bits (59), Expect = 8.9, Method: Composition-based stats. Identities = 9/30 (30%), Positives = 16/30 (53%) Query: 179 KDSKVHIFLAGDSSGGNIAHNVALRAGESG 208 + + I +AG S GG IA V+ + ++ Sbjct: 188 QVDQERIVIAGGSQGGGIALAVSALSKKAK 217 >2JH3-A nrPDB Length = 474 Score = 27.3 bits (59), Expect = 9.0, Method: Composition-based stats. Identities = 35/192 (18%), Positives = 58/192 (30%), Gaps = 40/192 (20%) Query: 43 RHLAEYLDRKVTANANPVDGVFSFDVLIDR---RINLLSRVYRPAYADQEQPPSILDLE- 98 RHLAE R P G+F +D ++L + V P + DL Sbjct: 285 RHLAERGGRLGEVLLTPYGGLFELRHTLDEGRATLDLQTVV---------TPEGLRDLTA 335 Query: 99 KPVDGDIVPVILFFHGGSFAHSSANSAIYDTLCRRLVGLCKCVVVSVNYRRAPENPYPCA 158 + G P+ R L + V+ + R E YP Sbjct: 336 RDEAGRWRPI--------------------RTWRTLPRGWRAVLSPADLRLGLELLYPAV 375 Query: 159 YDDGWI----ALNWVNSRSWLKSKKDSKVHIFLAGDSSGGNIAH---NVALRAGESGIDV 211 ++ + L+W S + + + + A +A LR Sbjct: 376 IEESYAHEHRRLHWTPWMSTARRQTGTLARVQRATPDQVDTVAAQVCASCLRTRLWAGHT 435 Query: 212 LGNILLNPMFGG 223 LG + + + GG Sbjct: 436 LGQTIFSGVPGG 447 >2X26-A nrPDB Length = 308 Score = 27.3 bits (59), Expect = 9.5, Method: Composition-based stats. Identities = 11/59 (18%), Positives = 27/59 (45%), Gaps = 11/59 (18%) Query: 45 LAEYLDRKVTANANPVDG-----------VFSFDVLIDRRINLLSRVYRPAYADQEQPP 92 +A YLD + PV+ +F + L+ +++++ R+++P + +Q Sbjct: 238 IASYLDHRPPTTIKPVNAEVAALQQQTADLFYENRLVPKKVDIRQRIWQPTQLEGKQLE 296 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.315 0.135 0.376 Lambda K H 0.267 0.0412 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,169,362 Number of Sequences: 36641 Number of extensions: 582584 Number of successful extensions: 1529 Number of sequences better than 10.0: 72 Number of HSP's better than 10.0 without gapping: 48 Number of HSP's successfully gapped in prelim test: 59 Number of HSP's that attempted gapping in prelim test: 1366 Number of HSP's gapped (non-prelim): 110 length of query: 345 length of database: 10,336,785 effective HSP length: 98 effective length of query: 247 effective length of database: 6,745,967 effective search space: 1666253849 effective search space used: 1666253849 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.5 bits) S2: 59 (27.3 bits)