BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9LT15 (514 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6H7D-A nrPDB 1048 0.0 4LDS-A nrPDB 213 2e-55 4GC0-A nrPDB 199 2e-51 4ZWB-A nrPDB 177 1e-44 4YB9-D nrPDB 166 2e-41 4YBQ-A nrPDB 164 1e-40 5EQH-A nrPDB 159 3e-39 4J05-A nrPDB 39 0.004 6MUU-A nrPDB 32 0.60 3HQ2-A nrPDB 32 0.97 4APS-A nrPDB 31 1.3 2VZX-A nrPDB 31 1.6 4IKY-A nrPDB 31 1.6 5NF8-A nrPDB 30 2.9 2PAN-A nrPDB 28 7.6 >6H7D-A nrPDB Length = 521 Score = 1048 bits (2709), Expect = 0.0, Method: Compositional matrix adjust. Identities = 513/513 (100%), Positives = 513/513 (100%) Query: 2 AGGAFVSEGGGGGRSYEGGVTAFVIMTCIVAAMGGLLFGYDLGISGGVTSMEEFLTKFFP 61 AGGAFVSEGGGGGRSYEGGVTAFVIMTCIVAAMGGLLFGYDLGISGGVTSMEEFLTKFFP Sbjct: 3 AGGAFVSEGGGGGRSYEGGVTAFVIMTCIVAAMGGLLFGYDLGISGGVTSMEEFLTKFFP 62 Query: 62 QVESQMKKAKHDTAYCKFDNQMLQLFTSSLYLAALVASFMASVITRKHGRKVSMFIGGLA 121 QVESQMKKAKHDTAYCKFDNQMLQLFTSSLYLAALVASFMASVITRKHGRKVSMFIGGLA Sbjct: 63 QVESQMKKAKHDTAYCKFDNQMLQLFTSSLYLAALVASFMASVITRKHGRKVSMFIGGLA 122 Query: 122 FLIGALFNAFAVNVSMLIIGRLLLGVGVGFANQSTPVYLSEMAPAKIRGALNIGFQMAIT 181 FLIGALFNAFAVNVSMLIIGRLLLGVGVGFANQSTPVYLSEMAPAKIRGALNIGFQMAIT Sbjct: 123 FLIGALFNAFAVNVSMLIIGRLLLGVGVGFANQSTPVYLSEMAPAKIRGALNIGFQMAIT 182 Query: 182 IGILVANLINYGTSKMAQHGWRVSLGLAAVPAVVMVIGSFILPDTPNSMLERGKNEEAKQ 241 IGILVANLINYGTSKMAQHGWRVSLGLAAVPAVVMVIGSFILPDTPNSMLERGKNEEAKQ Sbjct: 183 IGILVANLINYGTSKMAQHGWRVSLGLAAVPAVVMVIGSFILPDTPNSMLERGKNEEAKQ 242 Query: 242 MLKKIRGADNVDHEFQDLIDAVEAAKKVENPWKNIMESKYRPALIFCSAIPFFQQITGIN 301 MLKKIRGADNVDHEFQDLIDAVEAAKKVENPWKNIMESKYRPALIFCSAIPFFQQITGIN Sbjct: 243 MLKKIRGADNVDHEFQDLIDAVEAAKKVENPWKNIMESKYRPALIFCSAIPFFQQITGIN 302 Query: 302 VIMFYAPVLFKTLGFGDDAALMSAVITGVVNMLSTFVSIYAVDRYGRRLLFLEGGIQMFI 361 VIMFYAPVLFKTLGFGDDAALMSAVITGVVNMLSTFVSIYAVDRYGRRLLFLEGGIQMFI Sbjct: 303 VIMFYAPVLFKTLGFGDDAALMSAVITGVVNMLSTFVSIYAVDRYGRRLLFLEGGIQMFI 362 Query: 362 CQLLVGSFIGARFGTSGTGTLTPATADWILAFICVYVAGFAWSWGPLGWLVPSEICPLEI 421 CQLLVGSFIGARFGTSGTGTLTPATADWILAFICVYVAGFAWSWGPLGWLVPSEICPLEI Sbjct: 363 CQLLVGSFIGARFGTSGTGTLTPATADWILAFICVYVAGFAWSWGPLGWLVPSEICPLEI 422 Query: 422 RPAGQAINVSVNMFFTFLIGQFFLTMLCHMKFGLFYFFASMVAIMTVFIYFLLPETKGVP 481 RPAGQAINVSVNMFFTFLIGQFFLTMLCHMKFGLFYFFASMVAIMTVFIYFLLPETKGVP Sbjct: 423 RPAGQAINVSVNMFFTFLIGQFFLTMLCHMKFGLFYFFASMVAIMTVFIYFLLPETKGVP 482 Query: 482 IEEMGRVWKQHWFWKKYIPEDAIIGGHDDNNTN 514 IEEMGRVWKQHWFWKKYIPEDAIIGGHDDNNTN Sbjct: 483 IEEMGRVWKQHWFWKKYIPEDAIIGGHDDNNTN 515 >4LDS-A nrPDB Length = 446 Score = 213 bits (542), Expect = 2e-55, Method: Compositional matrix adjust. Identities = 133/405 (32%), Positives = 224/405 (55%), Gaps = 22/405 (5%) Query: 86 LFTSSLYLAALVASFMASVITRKHGRKVSMFIGGLAFLIGALFNAFAVNVSMLIIGRLLL 145 + SS+ + A+V + + + K GR+ + + + F+IGAL A + N+++LIIGRL++ Sbjct: 46 IVVSSMLIGAIVGAGSSGPLADKLGRRRLVMLIAIVFIIGALILAASTNLALLIIGRLII 105 Query: 146 GVGVGFANQSTPVYLSEMAPAKIRGALNIGFQMAITIGILVANLINYGTSKMAQHGWRVS 205 G+ VG + + PVYLSEMAP + RG+L Q+ ITIGIL A L+NY + + GWR Sbjct: 106 GLAVGGSMSTVPVYLSEMAPTEYRGSLGSLNQLMITIGILAAYLVNYAFADI--EGWRWM 163 Query: 206 LGLAAVPAVVMVIGSFILPDTPNSMLERGKNEEAKQMLKKIRGADNVDHEFQDL--IDAV 263 LGLA VP+V++++G + +P++P +LE E A+Q++K +D E +++ I+A+ Sbjct: 164 LGLAVVPSVILLVGIYFMPESPRWLLENRNEEAARQVMKITYDDSEIDKELKEMKEINAI 223 Query: 264 EAAKKVENPWKNIMESKYRPALIFCSAIPFFQQITGINVIMFYAPVLFKTLGFGDDAALM 323 E+ W I LI FQQ GIN ++FY+ +F G G+ A+++ Sbjct: 224 S-----ESTWTVIKSPWLGRILIVGCIFAIFQQFIGINAVIFYSSSIFAKAGLGEAASIL 278 Query: 324 SAVITGVVNMLSTFVSIYAVDRYGRRLLFLEGGIQMFICQLLVGSFIGARFGTSGTGTLT 383 +V G +N+L T V+I+ VD+ R+ L + G I M L++ I T+ Sbjct: 279 GSVGIGTINVLVTIVAIFVVDKIDRKKLLVGGNIGMIASLLIMAILI---------WTIG 329 Query: 384 PATADWILAFIC--VYVAGFAWSWGPLGWLVPSEICPLEIRPAGQAINVSVNMFFTFLIG 441 A++ WI+ +C +++ F SWGP+ W++ E+ P+ R A I+ V T ++ Sbjct: 330 IASSAWII-IVCLSLFIVFFGISWGPVLWVMLPELFPMRARGAATGISALVLNIGTLIVS 388 Query: 442 QFFLTMLCHMKFG-LFYFFASMVAIMTVFIYFLLPETKGVPIEEM 485 FF + + +F FA + + +F+ LPET+G +EE+ Sbjct: 389 LFFPILSDALSTEWVFLIFAFIGVLAMIFVIKFLPETRGRSLEEI 433 >4GC0-A nrPDB Length = 491 Score = 199 bits (507), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 147/502 (29%), Positives = 246/502 (49%), Gaps = 62/502 (12%) Query: 22 TAFVIMTCIVAAMGGLLFGYDLG-ISGGVTSMEEFLTKFFPQVESQMKKAKHDTAYCKFD 80 ++++ +VA +GGLLFGYD ISG V S+ PQ S+ Sbjct: 7 SSYIFSITLVATLGGLLFGYDTAVISGTVESLNTVFVA--PQNLSESAA----------- 53 Query: 81 NQMLQLFTSSLYLAALVASFMASVITRKHGRKVSMFIGGLAFLIGALFNAF------AVN 134 N +L +S + ++ + + + GR+ S+ I + F I + +A+ ++N Sbjct: 54 NSLLGFCVASALIGCIIGGALGGYCSNRFGRRDSLKIAAVLFFISGVGSAWPELGFTSIN 113 Query: 135 ------------VSMLIIGRLLLGVGVGFANQSTPVYLSEMAPAKIRGALNIGFQMAITI 182 V +I R++ G+GVG A+ +P+Y++E+APA IRG L Q AI Sbjct: 114 PDNTVPVYLAGYVPEFVIYRIIGGIGVGLASMLSPMYIAELAPAHIRGKLVSFNQFAIIF 173 Query: 183 GILVANLINY------GTSKMAQHGWRVSLGLAAVPAVVMVIGSFILPDTPNSMLERGKN 236 G L+ +NY S + GWR +PA++ ++ + +P++P ++ RGK Sbjct: 174 GQLLVYCVNYFIARSGDASWLNTDGWRYMFASECIPALLFLMLLYTVPESPRWLMSRGKQ 233 Query: 237 EEAKQMLKKIRGADNVDHEFQDLIDAVEAAKKVENPWKNIMESKYRPALIFCSAIPFFQQ 296 E+A+ +L+KI G Q++ +++ +K + +M ++ + FQQ Sbjct: 234 EQAEGILRKIMGNTLATQAVQEIKHSLDHGRKTGG--RLLMFGV--GVIVIGVMLSIFQQ 289 Query: 297 ITGINVIMFYAPVLFKTLGFGDDAALMSAVITGVVNMLSTFVSIYAVDRYGRRLLFLEGG 356 GINV+++YAP +FKTLG D AL+ +I GV+N+ T ++I VD++GR+ L + G Sbjct: 290 FVGINVVLYYAPEVFKTLGASTDIALLQTIIVGVINLTFTVLAIMTVDKFGRKPLQIIGA 349 Query: 357 IQMFICQLLVGSF-IGARFGTSGTGTLTPATADWILAFICVYVAGFAWSWGPLGWLVPSE 415 + M I G F +G F T G + L + YVA FA SWGP+ W++ SE Sbjct: 350 LGMAI-----GMFSLGTAFYTQAPGIVA-------LLSMLFYVAAFAMSWGPVCWVLLSE 397 Query: 416 ICPLEIRPAGQAINVSVNMFFTFLIGQFFLTM------LCHMKFGLFYF-FASMVAIMTV 468 I P IR AI V+ + + F M + H G Y+ + M + + Sbjct: 398 IFPNAIRGKALAIAVAAQWLANYFVSWTFPMMDKNSWLVAHFHNGFSYWIYGCMGVLAAL 457 Query: 469 FIYFLLPETKGVPIEEMGRVWK 490 F++ +PETKG +EE+ +W+ Sbjct: 458 FMWKFVPETKGKTLEELEALWE 479 >4ZWB-A nrPDB Length = 518 Score = 177 bits (449), Expect = 1e-44, Method: Compositional matrix adjust. Identities = 131/492 (26%), Positives = 230/492 (46%), Gaps = 35/492 (7%) Query: 12 GGGRSYEGGVTAFVIMTCIVAAMGGLLFGYDLGISGGVTSMEEFLTKFFPQVESQMKKAK 71 G G VT +I VA +G FGY+ G+ + + E+ + +F + + A Sbjct: 19 GSGHMGTQKVTPALIFAITVATIGSFQFGYNTGV---INAPEKIIKEFITKTLTDKGNAP 75 Query: 72 HDTAYCKFDNQMLQLFTSSLYLAALVASFMASVITRKHGRKVSMFIGGLAFLIGALFNAF 131 + L + + ++ SF + + GR+ SM I L + G F Sbjct: 76 PSEVLL---TSLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGL 132 Query: 132 ---AVNVSMLIIGRLLLGVGVGFANQSTPVYLSEMAPAKIRGALNIGFQMAITIGILVAN 188 A +V MLI+GRL++G+ G P+Y+ E++P +RGA Q+ I +GILVA Sbjct: 133 CKVAKSVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQ 192 Query: 189 LINYGTSKMAQHGWRVSLGLAAVPAVVMVIGSFILPDTPNSML-ERGKNEEAKQMLKKIR 247 + ++ W + LG +PA++ P++P +L R + E AKQ+L+++ Sbjct: 193 IFGLEFILGSEELWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLW 252 Query: 248 GADNVDHEFQDLIDAVEAAKKVENPWKNIME----SKYRPALIFCSAIPFFQQITGINVI 303 G +V + Q++ D E+A+ + ++E S YR +I + QQ++GIN + Sbjct: 253 GTQDVSQDIQEMKD--ESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAV 310 Query: 304 MFYAPVLFKTLGFGDDAALMSAVITGVVNMLSTFVSIYAVDRYGRRLLFLEGGIQMFICQ 363 +Y+ +FK G + + + + GVVN + T VS++ V+R GRR L + G M C Sbjct: 311 FYYSTGIFKDAGVQE--PIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCS 368 Query: 364 LLVGSFIGARFGTSGTGTLTPATADWILAFIC-----VYVAGFAWSWGPLGWLVPSEICP 418 L+ + + +G ++F+C V+VA F GP+ W + +E+ Sbjct: 369 TLMTVSLLLKDNYNG------------MSFVCIGAILVFVAFFEIGPGPIPWFIVAELFS 416 Query: 419 LEIRPAGQAINVSVNMFFTFLIGQFFLTMLCHMKFGLFYFFASMVAIMTVFIYFLLPETK 478 RPA A+ N FL+G F + ++ +F F + F +F +PET+ Sbjct: 417 QGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHYLGAYVFIIFTGFLITFLAFTFFKVPETR 476 Query: 479 GVPIEEMGRVWK 490 G E++ R ++ Sbjct: 477 GRTFEDITRAFE 488 >4YB9-D nrPDB Length = 479 Score = 166 bits (421), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 133/479 (27%), Positives = 228/479 (47%), Gaps = 24/479 (5%) Query: 18 EGGVTAFVIMTCIVAAMGG-LLFGYDLGISGGVTSMEEFLTKFFPQVESQMKKAKHDTAY 76 EG +T +++ ++AA G +GY++ + S EF+ F+ + Y Sbjct: 10 EGRLTPVIVLATLIAAFGSSFQYGYNVA---AINSPSEFMKDFYAYTYYDRVGEYMNEFY 66 Query: 77 CKFDNQMLQLFTSSLY-LAALVASFMASVITRKHGRKVSMFIGGLAFLIGAL---FNAFA 132 +L T S++ + S M + GRK ++ + ++ AL F+ A Sbjct: 67 LT----LLWSVTVSMFPFGGFLGSLMVGPLVNNLGRKGTLLFNNIFSIVPALLMGFSELA 122 Query: 133 VNVSMLIIGRLLLGVGVGFANQSTPVYLSEMAPAKIRGALNIGFQMAITIGILVANLINY 192 + M+I+ R+L+G+ G ++ P+YL E+AP RGAL + Q+ ITIGILVA + Sbjct: 123 KSFEMIIVARVLVGICAGLSSNVVPMYLGELAPKNWRGALGVVPQLFITIGILVAQIFGL 182 Query: 193 GTSKMAQHGWRVSLGLAAVPAVVMVIGSFILPDTPNSMLERGKNE-EAKQMLKKIRGADN 251 + + GW + LGL +PAV+ ++ P++P +L + K+E AK L+++RG + Sbjct: 183 RSLLANEEGWPILLGLTGIPAVLQLLFLPFFPESPRYLLIQKKDEAAAKSALRRLRGWHD 242 Query: 252 VDHEFQDLIDAVEAAKKVE--NPWKNIMESKYRPALIFCSAIPFFQQITGINVIMFYAPV 309 VD E +++++ A K V + K R +I + QQ++G+N I +YA Sbjct: 243 VDAEIEEILEEDRAEKAVGFISVLKLFKMRSLRWQVISIIVLMAGQQLSGVNAIYYYADQ 302 Query: 310 LFKTLGFGDDAALMSAVITGVVNMLSTFVSIYAVDRYGRRLLFLEGGIQMFI-CQLLVGS 368 ++ + G +D TG VN+L T +I+ V+ GRR L L G F C +L G+ Sbjct: 303 IYLSAGVNEDDVQYVTAGTGAVNVLITVCAIFVVELMGRRFLLLLGFSVCFTACCVLTGA 362 Query: 369 FIGARFGTSGTGTLTPATADWILAFICVYVAGFAWSWGPLGWLVPSEICPLEIRPAGQAI 428 + P + +A + YV G A P+ L+ +EI RPA + Sbjct: 363 -----LALQDVISWMPYVS---IACVISYVIGHALGPSPIPALLVTEIFLQSSRPAAYMV 414 Query: 429 NVSVNMFFTFLIGQFFLTMLCHMKFGLFYFFASMVAIMTVFIYFLLPETKGVPIEEMGR 487 +V+ F +G F + + F FA + + TV+I+ ++PETK E+ R Sbjct: 415 AGTVHWLSNFTVGLVFPFIQVGLGAYSFVIFAVICLLTTVYIFLIIPETKSKTFIEINR 473 >4YBQ-A nrPDB Length = 508 Score = 164 bits (414), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 133/492 (27%), Positives = 230/492 (46%), Gaps = 22/492 (4%) Query: 19 GGVTAFVIMTCIVAAMGG-LLFGYDLGISGGVTSMEEFLTKFFPQVESQMKKAKHDTAYC 77 G +T + + +AA G +GY++ V S EF+ +F+ K ++ Sbjct: 10 GKLTLVLALATFLAAFGSSFQYGYNVA---AVNSPSEFMQQFYYDTYYDRNKENIES--- 63 Query: 78 KFDNQMLQLFTSSLY-LAALVASFMASVITRKHGRKVSMFIGGLAFLIGALF---NAFAV 133 F +L T S++ + S M + GRK ++ + ++ A+ + A Sbjct: 64 -FTLTLLWSLTVSMFPFGGFIGSLMVGFLVNNLGRKGALLFNNIFSILPAILMGCSKIAK 122 Query: 134 NVSMLIIGRLLLGVGVGFANQSTPVYLSEMAPAKIRGALNIGFQMAITIGILVANLINYG 193 + ++I RLL+G+ G ++ P+YL E+AP +RGAL + Q+ IT+GILVA L Sbjct: 123 SFEIIIASRLLVGICAGISSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQLFGLR 182 Query: 194 TSKMAQHGWRVSLGLAAVPAVVMVIGSFILPDTPNSMLERGKNEE-AKQMLKKIRGADNV 252 + ++ GW + LGL VPA + ++ P++P +L + KNE A++ L+ +RG +V Sbjct: 183 SVLASEEGWPILLGLTGVPAGLQLLLLPFFPESPRYLLIQKKNESAAEKALQTLRGWKDV 242 Query: 253 DHEFQDLI--DAVEAAKKVENPWKNIMESKYRPALIFCSAIPFFQQITGINVIMFYAPVL 310 D E +++ D E A + WK R LI + QQ++G+N I +YA + Sbjct: 243 DMEMEEIRKEDEAEKAAGFISVWKLFRMQSLRWQLISTIVLMAGQQLSGVNAIYYYADQI 302 Query: 311 FKTLGFGDDAALMSAVITGVVNMLSTFVSIYAVDRYGRRLLFLEGGIQMFICQLLVGSFI 370 + + G + TG VN+ T V+++ V+ +GRR L L G F L + Sbjct: 303 YLSAGVKSNDVQYVTAGTGAVNVFMTMVTVFVVELWGRRNLLLIG----FSTCLTACIVL 358 Query: 371 GARFGTSGTGTLTPATADWILAFICVYVAGFAWSWGPLGWLVPSEICPLEIRPAGQAINV 430 T + P + + + VYV G A P+ L +EI RP+ I Sbjct: 359 TVALALQNTISWMPYVS---IVCVIVYVIGHAVGPSPIPALFITEIFLQSSRPSAYMIGG 415 Query: 431 SVNMFFTFLIGQFFLTMLCHMKFGLFYFFASMVAIMTVFIYFLLPETKGVPIEEMGRVWK 490 SV+ F++G F + + F FA + + T++I+ ++PETKG E+ +++ Sbjct: 416 SVHWLSNFIVGLIFPFIQVGLGPYSFIIFAIICLLTTIYIFMVVPETKGRTFVEINQIFA 475 Query: 491 QHWFWKKYIPED 502 + PE Sbjct: 476 KKNKVSDVYPEK 487 >5EQH-A nrPDB Length = 492 Score = 159 bits (401), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 124/475 (26%), Positives = 225/475 (47%), Gaps = 39/475 (8%) Query: 32 AAMGGLLFGYDLGISGGVTSMEEFLTKFFPQVESQMKKAKHDTAYCKFDNQMLQLFTSSL 91 A +G L FGY+ G+ + + ++ + +F+ Q H + L++ S+ Sbjct: 19 AVLGSLQFGYNTGV---INAPQKVIEEFYNQTWV------HRYGESILPTTLTTLWSLSV 69 Query: 92 YL---AALVASFMASVITRKHGRKVSMFIGGLAFLIGAL---FNAFAVNVSMLIIGRLLL 145 + ++ SF + + GR+ SM + L + A+ F+ + MLI+GR ++ Sbjct: 70 AIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFII 129 Query: 146 GVGVGFANQSTPVYLSEMAPAKIRGALNIGFQMAITIGILVANLINYGTSKMAQHGWRVS 205 GV G P+Y+ E++P +RGAL Q+ I +GIL+A + + + W + Sbjct: 130 GVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDLWPLL 189 Query: 206 LGLAAVPAVVMVIGSFILPDTPNSML-ERGKNEEAKQMLKKIRGADNVDHEFQDLIDAVE 264 L + +PA++ I P++P +L R + AK +LKK+RG +V H+ Q++ + E Sbjct: 190 LSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHDLQEMKE--E 247 Query: 265 AAKKVENPWKNIME----SKYRPALIFCSAIPFFQQITGINVIMFYAPVLFKTLGFGDDA 320 + + + I+E YR ++ + QQ++GIN + +Y+ +F+ G Sbjct: 248 SRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGV--QQ 305 Query: 321 ALMSAVITGVVNMLSTFVSIYAVDRYGRRLLFLEGGIQMFICQLLVGSFIGARFGTSGTG 380 + + + +G+VN T VS++ V+R GRR L L G M C +L+ T Sbjct: 306 PVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILM---------TIALA 356 Query: 381 TLTPATADWILAFICV--YVAGFAWSWGPLGWLVPSEICPLEIRPAGQAINVSVNMFFTF 438 L L+ + + +VA F GP+ W + +E+ RPA A+ N F Sbjct: 357 LLEQLPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNF 416 Query: 439 LIGQFF--LTMLCHMKFGLFYFFASMVAIMTVFIYFLLPETKGVPIEEMGRVWKQ 491 ++G F + LC +F F ++ + +F YF +PETKG +E+ ++Q Sbjct: 417 IVGMCFQYVEQLCGPY--VFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQ 469 >4J05-A nrPDB Length = 530 Score = 39.3 bits (90), Expect = 0.004, Method: Compositional matrix adjust. Identities = 57/277 (20%), Positives = 105/277 (37%), Gaps = 42/277 (15%) Query: 26 IMTCIVAAMGGLLFGYDLGISGGVTSMEEFLTKFFPQVESQMKKAKHDTAYCKFDNQMLQ 85 I ++A +G L YDL I V M +FP+ Q Sbjct: 34 IKLVLLAGVGFFLDAYDLFIINQVAPM--LAQVYFPKT--------------GLPAQRQD 77 Query: 86 LFTSSLYLAALVASFMASVITRKHGRKVSMFIGGLAFLIGALFNAFAVN-------VSML 138 L ++ + +V M V+ GRK + ++ +F A + ++ + Sbjct: 78 LMKAAANIGCVVGQVMFGVLGDSFGRKFVYGKELILIIVATIFQMSAPSHWDGNRVLTWI 137 Query: 139 IIGRLLLGVGVGFANQSTPVYLSEMAPAKIRGAL------NIGFQMAITIGILVA----- 187 I R+ LG+G+G + +S+ A RG L N G+ +G LV Sbjct: 138 TICRVFLGIGIGGDYPMSATVVSDRANIHRRGTLLCFIFANQGW--GSFVGSLVTIVTIS 195 Query: 188 ---NLINYGTSKMAQHGWRVSLGLAAVPAVVMVIGSFILPDTPNSMLERGKNEEAKQMLK 244 + + G + WR+ +GL+ +PA + LP++ L R + + Sbjct: 196 GFKHRLKSGHTHDVDKAWRILIGLSLIPAFGTLYQRLTLPESRKFELTRDAASSSTVAID 255 Query: 245 KIRGADNVDHEFQDLIDAVEAAKKVENPWKNIMESKY 281 K + HE +D ++ +++ KV P I + ++ Sbjct: 256 K--KDHDATHEVKDAPESEKSSPKV-TPADAIDDDRH 289 >6MUU-A nrPDB Length = 791 Score = 32.0 bits (71), Expect = 0.60, Method: Compositional matrix adjust. Identities = 18/65 (27%), Positives = 34/65 (52%), Gaps = 8/65 (12%) Query: 120 LAFLIGALFNAFAVNVSMLIIGRLLLGVGVGFANQSTPVY-LSEMAPAKIRGALNIGFQM 178 LAF + FNA+ G+L L VG+G+ ++ TP+Y ++++ ++ A + G Sbjct: 616 LAFRVRRAFNAYTG-------GKLTLSVGLGYFDERTPIYRMADVVSERLDTAKDEGRNR 668 Query: 179 AITIG 183 +G Sbjct: 669 VFVVG 673 >3HQ2-A nrPDB Length = 501 Score = 31.6 bits (70), Expect = 0.97, Method: Compositional matrix adjust. Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 1/62 (1%) Query: 257 QDLIDAVEAAKKVENPWKNIMESKYRPALIFCS-AIPFFQQITGINVIMFYAPVLFKTLG 315 +D AVE AKK K I E++Y+ +I CS A +++ G + ++P L + + Sbjct: 79 EDTKKAVELAKKEYEENKKIPEAEYKEYVILCSKAETAWEEAKGKSDFSLFSPYLEQLIE 138 Query: 316 FG 317 F Sbjct: 139 FN 140 >4APS-A nrPDB Length = 491 Score = 31.2 bits (69), Expect = 1.3, Method: Compositional matrix adjust. Identities = 36/132 (27%), Positives = 61/132 (46%), Gaps = 7/132 (5%) Query: 82 QMLQLFTSSLYLAALVASFMASVITRKHGRKVSMFIGGLAFLIGALFNAFAVNVSMLIIG 141 ++ ++ S +YL+ + F+A R G + ++F GG+ ++G + A S L Sbjct: 58 SIMAIYASMVYLSGTIGGFVAD---RIIGARPAVFWGGVLIMLGHIVLALPFGASALFGS 114 Query: 142 RLLLGVGVGF--ANQSTPVYLSEMAPAKIRGALNIGFQMAITIGILVANLINYGTSKMAQ 199 +L+ +G GF N ST V + R A F I +G +A LI + A Sbjct: 115 IILIIIGTGFLKPNVSTLVGTLYDEHDRRRDAGFSIFVFGINLGAFIAPLIVGAAQEAA- 173 Query: 200 HGWRVSLGLAAV 211 G+ V+ LAA+ Sbjct: 174 -GYHVAFSLAAI 184 >2VZX-A nrPDB Length = 231 Score = 30.8 bits (68), Expect = 1.6, Method: Compositional matrix adjust. Identities = 22/68 (32%), Positives = 30/68 (44%), Gaps = 5/68 (7%) Query: 3 GGAFVSEGGGGGRSYEGGVTAFVIMTCIVAAMGGLLFGYDLGISGGVTSMEEFLTKFFPQ 62 G AFV EG G G+ YEG TA V L F YD+ ++ V TK+ Sbjct: 20 GHAFVIEGEGKGKPYEGTQTA----NLTVKEGAPLPFSYDI-LTTAVHYGNRVFTKYPED 74 Query: 63 VESQMKKA 70 + K++ Sbjct: 75 IPDYFKQS 82 >4IKY-A nrPDB Length = 507 Score = 30.8 bits (68), Expect = 1.6, Method: Compositional matrix adjust. Identities = 32/131 (24%), Positives = 63/131 (48%), Gaps = 7/131 (5%) Query: 83 MLQLFTSSLYLAALVASFMASVITRKHGRKVSMFIGGLAFLIGALFNAFAVNVSMLIIGR 142 ++ ++ + +Y++ ++ ++A R G ++F GGL + G + A V+ L + Sbjct: 69 IMSIYGALVYMSGIIGGWLAD---RVFGTSRAVFYGGLLIMAGHIALAIPGGVAALFVSM 125 Query: 143 LLLGVGVGFANQSTPVYLSEM-APAKIRGALNIG-FQMAITIGILVANLINYGTSKMAQH 200 L+ +G G + + +M P R F M I +G +A L+ GT+ M ++ Sbjct: 126 ALIVLGTGLLKPNVSSIVGDMYKPGDDRRDAGFSIFYMGINLGAFLAPLV-VGTAGM-KY 183 Query: 201 GWRVSLGLAAV 211 + + GLAAV Sbjct: 184 NFHLGFGLAAV 194 >5NF8-A nrPDB Length = 174 Score = 29.6 bits (65), Expect = 2.9, Method: Compositional matrix adjust. Identities = 20/61 (32%), Positives = 30/61 (49%), Gaps = 2/61 (3%) Query: 184 ILVANLINYGTSKMAQHGWRVSLGLAAVPAVVMVIGSFILPDTPNSMLERGKNEEAKQML 243 IL A + G AQ+ +R +GL A V +V GSFI + + + K E+ K+ Sbjct: 46 ILAAQNVRLGNKWKAQYYFRWRVGLQAATLVALVAGSFIYGTSGKEL--KAKEEQLKEKA 103 Query: 244 K 244 K Sbjct: 104 K 104 >2PAN-A nrPDB Length = 616 Score = 28.5 bits (62), Expect = 7.6, Method: Compositional matrix adjust. Identities = 12/38 (31%), Positives = 19/38 (50%) Query: 406 GPLGWLVPSEICPLEIRPAGQAINVSVNMFFTFLIGQF 443 GPLGW +P+ + P + +S + F FLI + Sbjct: 442 GPLGWTIPAALGVCAADPKRNVVAISGDFDFQFLIEEL 479 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6H7D-A nrPDB 618 e-177 4YBQ-A nrPDB 517 e-147 4ZWB-A nrPDB 509 e-144 4YB9-D nrPDB 499 e-141 5EQH-A nrPDB 472 e-133 4GC0-A nrPDB 424 e-119 4LDS-A nrPDB 387 e-108 Sequences not found previously or not previously below threshold: 4J05-A nrPDB 85 6e-17 6E9N-A nrPDB 42 8e-04 6EUQ-A nrPDB 37 0.020 3WDO-A nrPDB 32 0.70 2VZX-A nrPDB 30 3.0 6A8U-A nrPDB 30 3.1 4GA7-A nrPDB 29 4.9 1PQU-A nrPDB 28 8.8 3R4S-A nrPDB 28 8.9 >6H7D-A nrPDB Length = 521 Score = 618 bits (1594), Expect = e-177, Method: Composition-based stats. Identities = 513/513 (100%), Positives = 513/513 (100%) Query: 2 AGGAFVSEGGGGGRSYEGGVTAFVIMTCIVAAMGGLLFGYDLGISGGVTSMEEFLTKFFP 61 AGGAFVSEGGGGGRSYEGGVTAFVIMTCIVAAMGGLLFGYDLGISGGVTSMEEFLTKFFP Sbjct: 3 AGGAFVSEGGGGGRSYEGGVTAFVIMTCIVAAMGGLLFGYDLGISGGVTSMEEFLTKFFP 62 Query: 62 QVESQMKKAKHDTAYCKFDNQMLQLFTSSLYLAALVASFMASVITRKHGRKVSMFIGGLA 121 QVESQMKKAKHDTAYCKFDNQMLQLFTSSLYLAALVASFMASVITRKHGRKVSMFIGGLA Sbjct: 63 QVESQMKKAKHDTAYCKFDNQMLQLFTSSLYLAALVASFMASVITRKHGRKVSMFIGGLA 122 Query: 122 FLIGALFNAFAVNVSMLIIGRLLLGVGVGFANQSTPVYLSEMAPAKIRGALNIGFQMAIT 181 FLIGALFNAFAVNVSMLIIGRLLLGVGVGFANQSTPVYLSEMAPAKIRGALNIGFQMAIT Sbjct: 123 FLIGALFNAFAVNVSMLIIGRLLLGVGVGFANQSTPVYLSEMAPAKIRGALNIGFQMAIT 182 Query: 182 IGILVANLINYGTSKMAQHGWRVSLGLAAVPAVVMVIGSFILPDTPNSMLERGKNEEAKQ 241 IGILVANLINYGTSKMAQHGWRVSLGLAAVPAVVMVIGSFILPDTPNSMLERGKNEEAKQ Sbjct: 183 IGILVANLINYGTSKMAQHGWRVSLGLAAVPAVVMVIGSFILPDTPNSMLERGKNEEAKQ 242 Query: 242 MLKKIRGADNVDHEFQDLIDAVEAAKKVENPWKNIMESKYRPALIFCSAIPFFQQITGIN 301 MLKKIRGADNVDHEFQDLIDAVEAAKKVENPWKNIMESKYRPALIFCSAIPFFQQITGIN Sbjct: 243 MLKKIRGADNVDHEFQDLIDAVEAAKKVENPWKNIMESKYRPALIFCSAIPFFQQITGIN 302 Query: 302 VIMFYAPVLFKTLGFGDDAALMSAVITGVVNMLSTFVSIYAVDRYGRRLLFLEGGIQMFI 361 VIMFYAPVLFKTLGFGDDAALMSAVITGVVNMLSTFVSIYAVDRYGRRLLFLEGGIQMFI Sbjct: 303 VIMFYAPVLFKTLGFGDDAALMSAVITGVVNMLSTFVSIYAVDRYGRRLLFLEGGIQMFI 362 Query: 362 CQLLVGSFIGARFGTSGTGTLTPATADWILAFICVYVAGFAWSWGPLGWLVPSEICPLEI 421 CQLLVGSFIGARFGTSGTGTLTPATADWILAFICVYVAGFAWSWGPLGWLVPSEICPLEI Sbjct: 363 CQLLVGSFIGARFGTSGTGTLTPATADWILAFICVYVAGFAWSWGPLGWLVPSEICPLEI 422 Query: 422 RPAGQAINVSVNMFFTFLIGQFFLTMLCHMKFGLFYFFASMVAIMTVFIYFLLPETKGVP 481 RPAGQAINVSVNMFFTFLIGQFFLTMLCHMKFGLFYFFASMVAIMTVFIYFLLPETKGVP Sbjct: 423 RPAGQAINVSVNMFFTFLIGQFFLTMLCHMKFGLFYFFASMVAIMTVFIYFLLPETKGVP 482 Query: 482 IEEMGRVWKQHWFWKKYIPEDAIIGGHDDNNTN 514 IEEMGRVWKQHWFWKKYIPEDAIIGGHDDNNTN Sbjct: 483 IEEMGRVWKQHWFWKKYIPEDAIIGGHDDNNTN 515 >4YBQ-A nrPDB Length = 508 Score = 517 bits (1332), Expect = e-147, Method: Composition-based stats. Identities = 133/493 (26%), Positives = 230/493 (46%), Gaps = 22/493 (4%) Query: 18 EGGVTAFVIMTCIVAAMGG-LLFGYDLGISGGVTSMEEFLTKFFPQVESQMKKAKHDTAY 76 G +T + + +AA G +GY++ V S EF+ +F+ K ++ Sbjct: 9 TGKLTLVLALATFLAAFGSSFQYGYNVA---AVNSPSEFMQQFYYDTYYDRNKENIES-- 63 Query: 77 CKFDNQMLQLFTSSLY-LAALVASFMASVITRKHGRKVSMFIGGLAFLIGALF---NAFA 132 F +L T S++ + S M + GRK ++ + ++ A+ + A Sbjct: 64 --FTLTLLWSLTVSMFPFGGFIGSLMVGFLVNNLGRKGALLFNNIFSILPAILMGCSKIA 121 Query: 133 VNVSMLIIGRLLLGVGVGFANQSTPVYLSEMAPAKIRGALNIGFQMAITIGILVANLINY 192 + ++I RLL+G+ G ++ P+YL E+AP +RGAL + Q+ IT+GILVA L Sbjct: 122 KSFEIIIASRLLVGICAGISSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQLFGL 181 Query: 193 GTSKMAQHGWRVSLGLAAVPAVVMVIGSFILPDTPNSMLERGKNE-EAKQMLKKIRGADN 251 + ++ GW + LGL VPA + ++ P++P +L + KNE A++ L+ +RG + Sbjct: 182 RSVLASEEGWPILLGLTGVPAGLQLLLLPFFPESPRYLLIQKKNESAAEKALQTLRGWKD 241 Query: 252 VDHEFQDLI--DAVEAAKKVENPWKNIMESKYRPALIFCSAIPFFQQITGINVIMFYAPV 309 VD E +++ D E A + WK R LI + QQ++G+N I +YA Sbjct: 242 VDMEMEEIRKEDEAEKAAGFISVWKLFRMQSLRWQLISTIVLMAGQQLSGVNAIYYYADQ 301 Query: 310 LFKTLGFGDDAALMSAVITGVVNMLSTFVSIYAVDRYGRRLLFLEGGIQMFICQLLVGSF 369 ++ + G + TG VN+ T V+++ V+ +GRR L L G F L Sbjct: 302 IYLSAGVKSNDVQYVTAGTGAVNVFMTMVTVFVVELWGRRNLLLIG----FSTCLTACIV 357 Query: 370 IGARFGTSGTGTLTPATADWILAFICVYVAGFAWSWGPLGWLVPSEICPLEIRPAGQAIN 429 + T + P + + + VYV G A P+ L +EI RP+ I Sbjct: 358 LTVALALQNTISWMPYVS---IVCVIVYVIGHAVGPSPIPALFITEIFLQSSRPSAYMIG 414 Query: 430 VSVNMFFTFLIGQFFLTMLCHMKFGLFYFFASMVAIMTVFIYFLLPETKGVPIEEMGRVW 489 SV+ F++G F + + F FA + + T++I+ ++PETKG E+ +++ Sbjct: 415 GSVHWLSNFIVGLIFPFIQVGLGPYSFIIFAIICLLTTIYIFMVVPETKGRTFVEINQIF 474 Query: 490 KQHWFWKKYIPED 502 + PE Sbjct: 475 AKKNKVSDVYPEK 487 >4ZWB-A nrPDB Length = 518 Score = 509 bits (1311), Expect = e-144, Method: Composition-based stats. Identities = 131/503 (26%), Positives = 232/503 (46%), Gaps = 25/503 (4%) Query: 11 GGGGRSYEGGVTAFVIMTCIVAAMGGLLFGYDLGISGGVTSMEEFLTKFFPQVESQMKKA 70 G G VT +I VA +G FGY+ G+ + + E+ + +F + + A Sbjct: 18 AGSGHMGTQKVTPALIFAITVATIGSFQFGYNTGV---INAPEKIIKEFITKTLTDKGNA 74 Query: 71 KHDTAYCKFDNQMLQLFTSSLYLAALVASFMASVITRKHGRKVSMFIGGLAFLIGALFNA 130 + L + + ++ SF + + GR+ SM I L + G F Sbjct: 75 PPSEVLL---TSLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMG 131 Query: 131 F---AVNVSMLIIGRLLLGVGVGFANQSTPVYLSEMAPAKIRGALNIGFQMAITIGILVA 187 A +V MLI+GRL++G+ G P+Y+ E++P +RGA Q+ I +GILVA Sbjct: 132 LCKVAKSVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVA 191 Query: 188 NLINYGTSKMAQHGWRVSLGLAAVPAVVMVIGSFILPDTPNSML-ERGKNEEAKQMLKKI 246 + ++ W + LG +PA++ P++P +L R + E AKQ+L+++ Sbjct: 192 QIFGLEFILGSEELWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRL 251 Query: 247 RGADNVDHEFQDLIDAVEAAKKVENPWKNIME----SKYRPALIFCSAIPFFQQITGINV 302 G +V + Q++ D E+A+ + ++E S YR +I + QQ++GIN Sbjct: 252 WGTQDVSQDIQEMKD--ESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINA 309 Query: 303 IMFYAPVLFKTLGFGDDAALMSAVITGVVNMLSTFVSIYAVDRYGRRLLFLEGGIQMFIC 362 + +Y+ +FK G + + + + GVVN + T VS++ V+R GRR L + G M C Sbjct: 310 VFYYSTGIFKDAGVQE--PIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFC 367 Query: 363 QLLVGSFIGARFGTSGTGTLTPATADWILAFICVYVAGFAWSWGPLGWLVPSEICPLEIR 422 L+ + + +G + + I V+VA F GP+ W + +E+ R Sbjct: 368 STLMTVSLLLKDNYNGM-------SFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPR 420 Query: 423 PAGQAINVSVNMFFTFLIGQFFLTMLCHMKFGLFYFFASMVAIMTVFIYFLLPETKGVPI 482 PA A+ N FL+G F + ++ +F F + F +F +PET+G Sbjct: 421 PAAMAVAGCSNWTSNFLVGLLFPSAAHYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTF 480 Query: 483 EEMGRVWKQHWFWKKYIPEDAII 505 E++ R ++ +D ++ Sbjct: 481 EDITRAFEGQAHGADRSGKDGVM 503 >4YB9-D nrPDB Length = 479 Score = 499 bits (1284), Expect = e-141, Method: Composition-based stats. Identities = 133/479 (27%), Positives = 227/479 (47%), Gaps = 24/479 (5%) Query: 18 EGGVTAFVIMTCIVAAMGG-LLFGYDLGISGGVTSMEEFLTKFFPQVESQMKKAKHDTAY 76 EG +T +++ ++AA G +GY++ + S EF+ F+ + Y Sbjct: 10 EGRLTPVIVLATLIAAFGSSFQYGYNVA---AINSPSEFMKDFYAYTYYDRVGEYMNEFY 66 Query: 77 CKFDNQMLQLFTSSLY-LAALVASFMASVITRKHGRKVSMFIGGLAFLIGAL---FNAFA 132 +L T S++ + S M + GRK ++ + ++ AL F+ A Sbjct: 67 L----TLLWSVTVSMFPFGGFLGSLMVGPLVNNLGRKGTLLFNNIFSIVPALLMGFSELA 122 Query: 133 VNVSMLIIGRLLLGVGVGFANQSTPVYLSEMAPAKIRGALNIGFQMAITIGILVANLINY 192 + M+I+ R+L+G+ G ++ P+YL E+AP RGAL + Q+ ITIGILVA + Sbjct: 123 KSFEMIIVARVLVGICAGLSSNVVPMYLGELAPKNWRGALGVVPQLFITIGILVAQIFGL 182 Query: 193 GTSKMAQHGWRVSLGLAAVPAVVMVIGSFILPDTPNSMLERGKNE-EAKQMLKKIRGADN 251 + + GW + LGL +PAV+ ++ P++P +L + K+E AK L+++RG + Sbjct: 183 RSLLANEEGWPILLGLTGIPAVLQLLFLPFFPESPRYLLIQKKDEAAAKSALRRLRGWHD 242 Query: 252 VDHEFQDLIDAVEAAKKVE--NPWKNIMESKYRPALIFCSAIPFFQQITGINVIMFYAPV 309 VD E +++++ A K V + K R +I + QQ++G+N I +YA Sbjct: 243 VDAEIEEILEEDRAEKAVGFISVLKLFKMRSLRWQVISIIVLMAGQQLSGVNAIYYYADQ 302 Query: 310 LFKTLGFGDDAALMSAVITGVVNMLSTFVSIYAVDRYGRRLLFLEGGIQMF-ICQLLVGS 368 ++ + G +D TG VN+L T +I+ V+ GRR L L G F C +L G Sbjct: 303 IYLSAGVNEDDVQYVTAGTGAVNVLITVCAIFVVELMGRRFLLLLGFSVCFTACCVLTG- 361 Query: 369 FIGARFGTSGTGTLTPATADWILAFICVYVAGFAWSWGPLGWLVPSEICPLEIRPAGQAI 428 + P + +A + YV G A P+ L+ +EI RPA + Sbjct: 362 ----ALALQDVISWMPYVS---IACVISYVIGHALGPSPIPALLVTEIFLQSSRPAAYMV 414 Query: 429 NVSVNMFFTFLIGQFFLTMLCHMKFGLFYFFASMVAIMTVFIYFLLPETKGVPIEEMGR 487 +V+ F +G F + + F FA + + TV+I+ ++PETK E+ R Sbjct: 415 AGTVHWLSNFTVGLVFPFIQVGLGAYSFVIFAVICLLTTVYIFLIIPETKSKTFIEINR 473 >5EQH-A nrPDB Length = 492 Score = 472 bits (1216), Expect = e-133, Method: Composition-based stats. Identities = 121/482 (25%), Positives = 225/482 (46%), Gaps = 29/482 (6%) Query: 20 GVTAFVIMTCIVAAMGGLLFGYDLGISGGVTSMEEFLTKFFPQVESQMKKAKHDTAYCKF 79 +T +++ A +G L FGY+ G+ + + ++ + +F+ Q + Sbjct: 7 KLTGRLMLAVGGAVLGSLQFGYNTGV---INAPQKVIEEFYNQTWVHRYGE---SILPTT 60 Query: 80 DNQMLQLFTSSLYLAALVASFMASVITRKHGRKVSMFIGGLAFLIGAL---FNAFAVNVS 136 + L + + ++ SF + + GR+ SM + L + A+ F+ + Sbjct: 61 LTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFE 120 Query: 137 MLIIGRLLLGVGVGFANQSTPVYLSEMAPAKIRGALNIGFQMAITIGILVANLINYGTSK 196 MLI+GR ++GV G P+Y+ E++P +RGAL Q+ I +GIL+A + + Sbjct: 121 MLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIM 180 Query: 197 MAQHGWRVSLGLAAVPAVVMVIGSFILPDTPNSML-ERGKNEEAKQMLKKIRGADNVDHE 255 + W + L + +PA++ I P++P +L R + AK +LKK+RG +V H+ Sbjct: 181 GNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHD 240 Query: 256 FQDLIDAVEAAKKVENPWKNIME----SKYRPALIFCSAIPFFQQITGINVIMFYAPVLF 311 Q++ + E+ + + I+E YR ++ + QQ++GIN + +Y+ +F Sbjct: 241 LQEMKE--ESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIF 298 Query: 312 KTLGFGDDAALMSAVITGVVNMLSTFVSIYAVDRYGRRLLFLEGGIQMFICQLLVGSFIG 371 + G + + + +G+VN T VS++ V+R GRR L L G M C +L+ Sbjct: 299 EKAGV--QQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILM----- 351 Query: 372 ARFGTSGTGTLTPATADWILAFICV--YVAGFAWSWGPLGWLVPSEICPLEIRPAGQAIN 429 T L L+ + + +VA F GP+ W + +E+ RPA A+ Sbjct: 352 ----TIALALLEQLPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVA 407 Query: 430 VSVNMFFTFLIGQFFLTMLCHMKFGLFYFFASMVAIMTVFIYFLLPETKGVPIEEMGRVW 489 N F++G F + +F F ++ + +F YF +PETKG +E+ + Sbjct: 408 GFSNWTSNFIVGMCFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGF 467 Query: 490 KQ 491 +Q Sbjct: 468 RQ 469 >4GC0-A nrPDB Length = 491 Score = 424 bits (1089), Expect = e-119, Method: Composition-based stats. Identities = 145/511 (28%), Positives = 242/511 (47%), Gaps = 60/511 (11%) Query: 16 SYEGGVTAFVIMTCIVAAMGGLLFGYDLG-ISGGVTSMEEFLTKFFPQVESQMKKAKHDT 74 ++++ +VA +GGLLFGYD ISG V S+ PQ S+ Sbjct: 1 MNTQYNSSYIFSITLVATLGGLLFGYDTAVISGTVESLNTVFVA--PQNLSESAA----- 53 Query: 75 AYCKFDNQMLQLFTSSLYLAALVASFMASVITRKHGRKVSMFIGGLAFLIGALFNAF--- 131 N +L +S + ++ + + + GR+ S+ I + F I + +A+ Sbjct: 54 ------NSLLGFCVASALIGCIIGGALGGYCSNRFGRRDSLKIAAVLFFISGVGSAWPEL 107 Query: 132 ---------------AVNVSMLIIGRLLLGVGVGFANQSTPVYLSEMAPAKIRGALNIGF 176 A V +I R++ G+GVG A+ +P+Y++E+APA IRG L Sbjct: 108 GFTSINPDNTVPVYLAGYVPEFVIYRIIGGIGVGLASMLSPMYIAELAPAHIRGKLVSFN 167 Query: 177 QMAITIGILVANLINY------GTSKMAQHGWRVSLGLAAVPAVVMVIGSFILPDTPNSM 230 Q AI G L+ +NY S + GWR +PA++ ++ + +P++P + Sbjct: 168 QFAIIFGQLLVYCVNYFIARSGDASWLNTDGWRYMFASECIPALLFLMLLYTVPESPRWL 227 Query: 231 LERGKNEEAKQMLKKIRGADNVDHEFQDLIDAVEAAKKVENPWKNIMESKYRPALIFCSA 290 + RGK E+A+ +L+KI G Q++ +++ +K + +M ++ Sbjct: 228 MSRGKQEQAEGILRKIMGNTLATQAVQEIKHSLDHGRKTGG--RLLMFGV--GVIVIGVM 283 Query: 291 IPFFQQITGINVIMFYAPVLFKTLGFGDDAALMSAVITGVVNMLSTFVSIYAVDRYGRRL 350 + FQQ GINV+++YAP +FKTLG D AL+ +I GV+N+ T ++I VD++GR+ Sbjct: 284 LSIFQQFVGINVVLYYAPEVFKTLGASTDIALLQTIIVGVINLTFTVLAIMTVDKFGRKP 343 Query: 351 LFLEGGIQMFICQLLVGSFIGARFGTSGTGTLTPATADWILAFICVYVAGFAWSWGPLGW 410 L + G + M I +G F T G + L + YVA FA SWGP+ W Sbjct: 344 LQIIGALGMAIGMF----SLGTAFYTQAPGIVA-------LLSMLFYVAAFAMSWGPVCW 392 Query: 411 LVPSEICPLEIRPAGQAINVSVNMFFTFLIGQFFLTM------LCHMKFGLFYF-FASMV 463 ++ SEI P IR AI V+ + + F M + H G Y+ + M Sbjct: 393 VLLSEIFPNAIRGKALAIAVAAQWLANYFVSWTFPMMDKNSWLVAHFHNGFSYWIYGCMG 452 Query: 464 AIMTVFIYFLLPETKGVPIEEMGRVWKQHWF 494 + +F++ +PETKG +EE+ +W+ Sbjct: 453 VLAALFMWKFVPETKGKTLEELEALWEPETK 483 >4LDS-A nrPDB Length = 446 Score = 387 bits (993), Expect = e-108, Method: Composition-based stats. Identities = 131/416 (31%), Positives = 224/416 (53%), Gaps = 16/416 (3%) Query: 79 FDNQMLQLFTSSLYLAALVASFMASVITRKHGRKVSMFIGGLAFLIGALFNAFAVNVSML 138 ++ + SS+ + A+V + + + K GR+ + + + F+IGAL A + N+++L Sbjct: 39 LNSTTEGIVVSSMLIGAIVGAGSSGPLADKLGRRRLVMLIAIVFIIGALILAASTNLALL 98 Query: 139 IIGRLLLGVGVGFANQSTPVYLSEMAPAKIRGALNIGFQMAITIGILVANLINYGTSKMA 198 IIGRL++G+ VG + + PVYLSEMAP + RG+L Q+ ITIGIL A L+NY + + Sbjct: 99 IIGRLIIGLAVGGSMSTVPVYLSEMAPTEYRGSLGSLNQLMITIGILAAYLVNYAFADI- 157 Query: 199 QHGWRVSLGLAAVPAVVMVIGSFILPDTPNSMLERGKNEEAKQMLKKIRGADNVDHEFQD 258 GWR LGLA VP+V++++G + +P++P +LE E A+Q++K +D E ++ Sbjct: 158 -EGWRWMLGLAVVPSVILLVGIYFMPESPRWLLENRNEEAARQVMKITYDDSEIDKELKE 216 Query: 259 LIDAVEAAKKVENPWKNIMESKYRPALIFCSAIPFFQQITGINVIMFYAPVLFKTLGFGD 318 + E E+ W I LI FQQ GIN ++FY+ +F G G+ Sbjct: 217 MK---EINAISESTWTVIKSPWLGRILIVGCIFAIFQQFIGINAVIFYSSSIFAKAGLGE 273 Query: 319 DAALMSAVITGVVNMLSTFVSIYAVDRYGRRLLFLEGGIQMFICQLLVGSFIGARFGTSG 378 A+++ +V G +N+L T V+I+ VD+ R+ L + G I M L++ I Sbjct: 274 AASILGSVGIGTINVLVTIVAIFVVDKIDRKKLLVGGNIGMIASLLIMAILI-------- 325 Query: 379 TGTLTPATADW-ILAFICVYVAGFAWSWGPLGWLVPSEICPLEIRPAGQAINVSVNMFFT 437 T+ A++ W I+ + +++ F SWGP+ W++ E+ P+ R A I+ V T Sbjct: 326 -WTIGIASSAWIIIVCLSLFIVFFGISWGPVLWVMLPELFPMRARGAATGISALVLNIGT 384 Query: 438 FLIGQFFLTMLCHMKFG-LFYFFASMVAIMTVFIYFLLPETKGVPIEEMGRVWKQH 492 ++ FF + + +F FA + + +F+ LPET+G +EE+ ++ Sbjct: 385 LIVSLFFPILSDALSTEWVFLIFAFIGVLAMIFVIKFLPETRGRSLEEIEYELRER 440 >4J05-A nrPDB Length = 530 Score = 85.5 bits (210), Expect = 6e-17, Method: Composition-based stats. Identities = 91/509 (17%), Positives = 172/509 (33%), Gaps = 81/509 (15%) Query: 26 IMTCIVAAMGGLLFGYDLGISGGVTSMEEFLTKFFPQVESQMKKAKHDTAYCKFDNQMLQ 85 I ++A +G L YDL I V M +FP+ Q Sbjct: 34 IKLVLLAGVGFFLDAYDLFIINQVAPM--LAQVYFPKT--------------GLPAQRQD 77 Query: 86 LFTSSLYLAALVASFMASVITRKHGRKVSMFIGGLAFLIGALFNAFAVN-------VSML 138 L ++ + +V M V+ GRK + ++ +F A + ++ + Sbjct: 78 LMKAAANIGCVVGQVMFGVLGDSFGRKFVYGKELILIIVATIFQMSAPSHWDGNRVLTWI 137 Query: 139 IIGRLLLGVGVGFANQSTPVYLSEMAPAKIRGAL--------NIGFQMAITIGILVANLI 190 I R+ LG+G+G + +S+ A RG L G + + I+ + Sbjct: 138 TICRVFLGIGIGGDYPMSATVVSDRANIHRRGTLLCFIFANQGWGSFVGSLVTIVTISGF 197 Query: 191 NYGTSKMAQH----GWRVSLGLAAVPAVVMVIGSFILPDTPNSMLERGKNEEAKQMLKKI 246 + H WR+ +GL+ +PA + LP++ L R + + + Sbjct: 198 KHRLKSGHTHDVDKAWRILIGLSLIPAFGTLYQRLTLPESRKFELTR--DAASSSTVAID 255 Query: 247 RGADNVDHEFQDLIDAVEAAKKV-------ENPWKNIMESKYRPALIFC--SAIPFFQQI 297 + + HE +D ++ +++ KV ++ I K S F+ + Sbjct: 256 KKDHDATHEVKDAPESEKSSPKVTPADAIDDDRHGVIASKKAHWQEFVAYFSTWNHFRNL 315 Query: 298 TGINVIMFYAPVLFKTLGFGDDAALMSAVITG-------------VVNMLSTFV------ 338 G + F + F + L G N++ T + Sbjct: 316 LGSMLGWFLVDIAFYGINLNQSVVLAQIGFAGKTGDVYDKLFQLATGNIIVTALGFLPGY 375 Query: 339 --SIYAVDRYGRRLLFLEGGIQMFICQLLVGSFIGARFGTSGTGTLTPATADWILAFICV 396 +++ +D GR+ L G I + G F+ G P LA Sbjct: 376 YFTLFLIDIVGRKKLQFMGFI-------MSGLFLAILAGEIDHIGKGPL-----LACFTF 423 Query: 397 YVAGFAWSWGPLGWLVPSEICPLEIRPAGQAINVSVNMFFTFLIGQFFLTMLCHMKF-GL 455 F + ++V +E+ P IR + I+ + L F + + + Sbjct: 424 MQFFFNFGANTTTFIVAAELFPTRIRASAHGISAAAGKCGAILSSLVFNQLKAKIGTSAV 483 Query: 456 FYFFASMVAIMTVFIYFLLPETKGVPIEE 484 + F S + + + L+ ET GV +E Sbjct: 484 LWIFFSTCILGFISTF-LIDETMGVDPDE 511 >6E9N-A nrPDB Length = 460 Score = 41.6 bits (96), Expect = 8e-04, Method: Composition-based stats. Identities = 57/374 (15%), Positives = 116/374 (31%), Gaps = 23/374 (6%) Query: 102 ASVITRKHGRKVSMFIGGLAFLIGALFNAFAVNVSMLIIGRLLLGVGVGFANQSTPVYLS 161 + G +V+ FI + + LF FA + LI R + G+ A + ++ Sbjct: 86 GGWFLDRVGSRVTYFIAIFGWSVATLFQGFATGLMSLIGLRAITGIFEAPAFPTNNRMVT 145 Query: 162 EMAPAKIRGALNIGFQMAITIGILVANLINYGTSKMAQHGWRVSLGLAAVPAVVMVIGSF 221 P R + + +G +A L W + ++ + F Sbjct: 146 SWFPEHERASAVGFYTSGQFVG--LAFLTPLLIWIQEMLSWHWVFIVTGGIGIIWSLIWF 203 Query: 222 ILPDTPNSMLERGKNEEAKQMLKKIRGADNVDHEFQDLIDAVEAAKKVENPWKNIMESKY 281 + P L +G ++ ++ G + D + AK + + + Y Sbjct: 204 KVYQPPR--LTKGISKAELDYIRDGGGLVDGDAPVKKEARQPLTAKDWKLVFHRKLIGVY 261 Query: 282 RPALIFCSAIPFFQQITGINVIMFYAPVLFKTLGFGDDAALMSAVITGVVNMLSTFVSIY 341 S + FF + ++ L + G A + + + +S + Sbjct: 262 LGQFAVASTLWFF--------LTWFPNYLTQEKGITALKAGFMTTVPFLAAFVGVLLSGW 313 Query: 342 AVDRYGRRLLFLEGGIQM-FICQLLVGSFIGARFGTSGTGTLTPATADWILAFICVYVAG 400 D R+ L + IC LL+ + I T+ + A +A Sbjct: 314 VADLLVRKGFSLGFARKTPIICGLLISTCIMGANYTNDPMMIMCLMA----------LAF 363 Query: 401 FAWSWGPLGWLVPSEICPLEIRPAGQAINVSVNMFFTFLIGQFFLTMLCHMKFGLFYFFA 460 F + + W + S + P+ + + + + F + Sbjct: 364 FGNGFASITWSLVSSLAPMRLIGLTGGVFNFAGGLGGITVPLVVGYLAQGYGFAPALVYI 423 Query: 461 SMVAIMTVFIYFLL 474 S VA++ Y LL Sbjct: 424 SAVALIGALSYILL 437 >6EUQ-A nrPDB Length = 419 Score = 36.9 bits (84), Expect = 0.020, Method: Composition-based stats. Identities = 16/95 (16%), Positives = 38/95 (40%), Gaps = 2/95 (2%) Query: 55 FLTKFFPQVESQMKKAKHDTAYCKFDNQMLQLFTS--SLYLAALVASFMASVITRKHGRK 112 L +F + + M + ++ + + TS + + ++ ++ + GR+ Sbjct: 23 VLYEFSTYIGNDMIQPGMLAVVEQYQAGIDWVPTSMTAYLAGGMFLQWLLGPLSDRIGRR 82 Query: 113 VSMFIGGLAFLIGALFNAFAVNVSMLIIGRLLLGV 147 M G + F++ L A N+ + R L G+ Sbjct: 83 PVMLAGVVWFIVTCLAILLAQNIEQFTLLRFLQGI 117 >3WDO-A nrPDB Length = 453 Score = 31.9 bits (71), Expect = 0.70, Method: Composition-based stats. Identities = 26/132 (19%), Positives = 56/132 (42%), Gaps = 5/132 (3%) Query: 103 SVITRKHGRKVSMFIGGLAFLIGALFNAFAVNVSMLIIGRLLLGVGVGFANQSTPVYLSE 162 +++ + GRK + G F G++ A + ++ +I+GR L G G + LS+ Sbjct: 67 GLLSDRIGRKPLIVGGLAVFAAGSVIAALSDSIWGIILGRALQG--SGAIAAAVMALLSD 124 Query: 163 MAPAKIRGALNIGFQMAITIGILVANLINYGTSKMAQHGWRVSLGLAAVPAVVMVIG-SF 221 + + R + ++ GI A + G + G + A+ A + + Sbjct: 125 LTREQNRTKAMAF--IGVSFGITFAIAMVLGPIITHKLGLHALFWMIAILATTGIALTIW 182 Query: 222 ILPDTPNSMLER 233 ++P++ +L R Sbjct: 183 VVPNSSTHVLNR 194 >2VZX-A nrPDB Length = 231 Score = 29.6 bits (65), Expect = 3.0, Method: Composition-based stats. Identities = 24/75 (32%), Positives = 31/75 (41%), Gaps = 6/75 (8%) Query: 3 GGAFVSEGGGGGRSYEGGVTAFVIMTCIVAAMGGLLFGYDLGISGGVTSMEEFLTKFFPQ 62 G AFV EG G G+ YEG TA + V L F YD+ ++ V TK +P+ Sbjct: 20 GHAFVIEGEGKGKPYEGTQTANL----TVKEGAPLPFSYDI-LTTAVHYGNRVFTK-YPE 73 Query: 63 VESQMKKAKHDTAYC 77 K Y Sbjct: 74 DIPDYFKQSFPEGYS 88 >6A8U-A nrPDB Length = 149 Score = 29.6 bits (65), Expect = 3.1, Method: Composition-based stats. Identities = 8/68 (11%), Positives = 26/68 (38%), Gaps = 3/68 (4%) Query: 227 PNSMLERGKNEEAKQMLKK---IRGADNVDHEFQDLIDAVEAAKKVENPWKNIMESKYRP 283 P+ + G +E + + G ++ + Q++ + + A+ + N+ + R Sbjct: 70 PDWLKSNGFHEIEADVNDTSLLLSGDHSIQQQLQEVREDDDDAEMTHSVAVNVYPATSRM 129 Query: 284 ALIFCSAI 291 + + Sbjct: 130 PKLTIVVV 137 >4GA7-A nrPDB Length = 389 Score = 29.2 bits (64), Expect = 4.9, Method: Composition-based stats. Identities = 17/62 (27%), Positives = 25/62 (40%), Gaps = 3/62 (4%) Query: 244 KKIRGADNVDHEFQDLIDAVEAAKKVENPWKNIMESKYRPALIFCSAIPFFQQITGINVI 303 +K GAD +FQ A E A+K N W P L+ + ++ +N I Sbjct: 119 QKTYGADLASVDFQ---HASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAI 175 Query: 304 MF 305 F Sbjct: 176 YF 177 >1PQU-A nrPDB Length = 371 Score = 28.1 bits (61), Expect = 8.8, Method: Composition-based stats. Identities = 11/28 (39%), Positives = 16/28 (57%) Query: 478 KGVPIEEMGRVWKQHWFWKKYIPEDAII 505 K +P+EE+ ++ H W K IP D I Sbjct: 287 KDLPLEEIEQIIASHNEWVKVIPNDKEI 314 >3R4S-A nrPDB Length = 443 Score = 28.1 bits (61), Expect = 8.9, Method: Composition-based stats. Identities = 9/33 (27%), Positives = 19/33 (57%) Query: 296 QITGINVIMFYAPVLFKTLGFGDDAALMSAVIT 328 QI +N +YA +FK+ G++ + + ++ T Sbjct: 357 QIQPMNNTYYYASQIFKSNFNGENISGICSIGT 389 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.323 0.135 0.357 Lambda K H 0.267 0.0416 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 18,714,139 Number of Sequences: 36641 Number of extensions: 719568 Number of successful extensions: 2909 Number of sequences better than 10.0: 43 Number of HSP's better than 10.0 without gapping: 25 Number of HSP's successfully gapped in prelim test: 41 Number of HSP's that attempted gapping in prelim test: 2778 Number of HSP's gapped (non-prelim): 81 length of query: 514 length of database: 10,336,785 effective HSP length: 101 effective length of query: 413 effective length of database: 6,636,044 effective search space: 2740686172 effective search space used: 2740686172 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.5 bits) S2: 61 (28.1 bits)