BLASTP 2.2.23 [Feb-03-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.


Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= Q9LSV0
         (289 letters)

Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 
           36,641 sequences; 10,336,785 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

3DOJ-A nrPDB                                                          585   e-168
3PDU-A nrPDB                                                          328   1e-90
3PEF-A nrPDB                                                          326   8e-90
2UYY-A nrPDB                                                          278   2e-75
5XVH-A nrPDB                                                          162   2e-40
3CKY-A nrPDB                                                          144   3e-35
1VPD-A nrPDB                                                          138   2e-33
1YB4-A nrPDB                                                          131   3e-31
5JE8-A nrPDB                                                          120   8e-28
4DLL-A nrPDB                                                          117   5e-27
2GF2-A nrPDB                                                          109   1e-24
4GBJ-A nrPDB                                                           95   3e-20
5Y8M-A nrPDB                                                           89   2e-18
2CVZ-A nrPDB                                                           89   2e-18
3Q3C-A nrPDB                                                           86   2e-17
4D3S-A nrPDB                                                           81   6e-16
4D3F-A nrPDB                                                           80   1e-15
3G0O-A nrPDB                                                           78   4e-15
3QHA-A nrPDB                                                           77   1e-14
4OQZ-A nrPDB                                                           74   7e-14
5OCM-A nrPDB                                                           73   2e-13
3ZHB-A nrPDB                                                           73   2e-13
5U5G-A nrPDB                                                           68   6e-12
5G6R-A nrPDB                                                           66   2e-11
4OQY-A nrPDB                                                           65   4e-11
5A9T-A nrPDB                                                           64   1e-10
3L6D-A nrPDB                                                           59   3e-09
2W8Z-A nrPDB                                                           50   8e-07
6EOI-A nrPDB                                                           49   2e-06
2ZYA-A nrPDB                                                           49   2e-06
2IZ1-A nrPDB                                                           45   4e-05
6FQY-A nrPDB                                                           44   1e-04
4E21-A nrPDB                                                           42   2e-04
1PGJ-A nrPDB                                                           40   0.002
2P4Q-A nrPDB                                                           39   0.004
4GWK-A nrPDB                                                           38   0.005
1PGO-A nrPDB                                                           38   0.006
2HK7-A nrPDB                                                           36   0.015
4YPO-A nrPDB                                                           35   0.056
4DGS-A nrPDB                                                           33   0.10 
6C6P-A nrPDB                                                           32   0.23 
2D0I-A nrPDB                                                           32   0.30 
4WEQ-A nrPDB                                                           31   0.51 
2F1K-A nrPDB                                                           31   0.51 
6C55-A nrPDB                                                           31   0.58 
3PGJ-A nrPDB                                                           31   0.76 
1TXG-A nrPDB                                                           30   0.81 
5TSD-A nrPDB                                                           30   1.7  
3K96-A nrPDB                                                           29   2.5  
4N18-A nrPDB                                                           29   3.0  
1BG6-A nrPDB                                                           28   3.6  
1T0K-B nrPDB                                                           28   3.7  
5JOY-A nrPDB                                                           28   4.1  
6IUM-B nrPDB                                                           28   5.6  
3GGO-A nrPDB                                                           28   6.2  
2G5C-A nrPDB                                                           28   6.6  
4XA8-A nrPDB                                                           27   9.2  

>3DOJ-A nrPDB
          Length = 310

 Score =  585 bits (1508), Expect = e-168,   Method: Compositional matrix adjust.
 Identities = 289/289 (100%), Positives = 289/289 (100%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60
           MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT
Sbjct: 22  MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 81

Query: 61  IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120
           IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV
Sbjct: 82  IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 141

Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 180
           SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM
Sbjct: 142 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 201

Query: 181 MNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDM 240
           MNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDM
Sbjct: 202 MNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDM 261

Query: 241 RLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVKFSRE 289
           RLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVKFSRE
Sbjct: 262 RLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVKFSRE 310


>3PDU-A nrPDB
          Length = 287

 Score =  328 bits (842), Expect = 1e-90,   Method: Compositional matrix adjust.
 Identities = 164/282 (58%), Positives = 198/282 (70%)

Query: 4   GFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIAM 63
           GFLGLGIMG  M+ NL++ GF VTVWNR  +KC  LV  GA    SPAEV   C  TIAM
Sbjct: 5   GFLGLGIMGGPMAANLVRAGFDVTVWNRNPAKCAPLVALGARQASSPAEVCAACDITIAM 64

Query: 64  LSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSGS 123
           L+DP AA  V F   GVLE I  G+GYIDMSTVD ETS  I  A+T +GGRF+E PVSG+
Sbjct: 65  LADPAAAREVCFGANGVLEGIGGGRGYIDMSTVDDETSTAIGAAVTARGGRFLEAPVSGT 124

Query: 124 KKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMMNA 183
           KKPAEDG LIILAAGD++LF ++ PAF  LGK+  +LG+VG GA+MKL+VNMIMG MM A
Sbjct: 125 KKPAEDGTLIILAAGDQSLFTDAGPAFAALGKKCLHLGEVGQGARMKLVVNMIMGQMMTA 184

Query: 184 FSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDMRLA 243
             EG+ L    GL    LL++LD GAM NPMFKGKG  +    +P +FPLKH QKD+RLA
Sbjct: 185 LGEGMALGRNCGLDGGQLLEVLDAGAMANPMFKGKGQMLLSGEFPTSFPLKHMQKDLRLA 244

Query: 244 LALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVK 285
           + LGD     +  AA ANE+FK+AR+ G  D DF+AV   ++
Sbjct: 245 VELGDRLGQPLHGAATANESFKRARAAGHADEDFAAVFRVLE 286


>3PEF-A nrPDB
          Length = 287

 Score =  326 bits (835), Expect = 8e-90,   Method: Compositional matrix adjust.
 Identities = 159/279 (56%), Positives = 203/279 (72%)

Query: 4   GFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIAM 63
           GF+GLGIMG AM+ NL+K G  VT+WNR+  K +EL   GA    +P EV++ C  T AM
Sbjct: 5   GFIGLGIMGSAMAKNLVKAGCSVTIWNRSPEKAEELAALGAERAATPCEVVESCPVTFAM 64

Query: 64  LSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSGS 123
           L+DP AA  V F K GVLE I EG+GY+DMSTVD  TS +I  A+  KGGRF+E PVSGS
Sbjct: 65  LADPAAAEEVCFGKHGVLEGIGEGRGYVDMSTVDPATSQRIGVAVVAKGGRFLEAPVSGS 124

Query: 124 KKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMMNA 183
           KKPAEDG LIILAAGD+ L++E++P F+ +GK+  +LG VG GA+MKL+VNM+MG MM  
Sbjct: 125 KKPAEDGTLIILAAGDRNLYDEAMPGFEKMGKKIIHLGDVGKGAEMKLVVNMVMGGMMAC 184

Query: 184 FSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDMRLA 243
           F EGL L +K+GL++D +LD++  GAM NPMF  KG  +   ++ PAFPLKH QKD+RLA
Sbjct: 185 FCEGLALGEKAGLATDAILDVIGAGAMANPMFALKGGLIRDRNFAPAFPLKHMQKDLRLA 244

Query: 244 LALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIE 282
           +ALGD     +  +AAANE FK AR+ G GD DFSA+ +
Sbjct: 245 VALGDRVGQPLVASAAANELFKGARAAGFGDEDFSAIFK 283


>2UYY-A nrPDB
          Length = 316

 Score =  278 bits (710), Expect = 2e-75,   Method: Compositional matrix adjust.
 Identities = 140/282 (49%), Positives = 189/282 (67%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61
           ++GFLGLG+MG  +  NLLK G  VTVWNRT  KCD  ++ GA +  +PAEV+  C  T 
Sbjct: 32  KIGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKCDLFIQEGARLGRTPAEVVSTCDITF 91

Query: 62  AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121
           A +SDP AA  +V    GVL+ I  GK Y+DMSTVDA+T  ++ + I  +GGRF+E PVS
Sbjct: 92  ACVSDPKAAKDLVLGPSGVLQGIRPGKCYVDMSTVDADTVTELAQVIVSRGGRFLEAPVS 151

Query: 122 GSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMM 181
           G+++ + DG L+ILAAGD+ L+E+    F  +GK SF+LG+VGN AKM LIVNM+ GS M
Sbjct: 152 GNQQLSNDGMLVILAAGDRGLYEDCSSCFQAMGKTSFFLGEVGNAAKMMLIVNMVQGSFM 211

Query: 182 NAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDMR 241
              +EGL LA  +G S  TLLDIL+ G + +     K  ++ + ++ P F LK+ QKD+R
Sbjct: 212 ATIAEGLTLAQVTGQSQQTLLDILNQGQLASIFLDQKCQNILQGNFKPDFYLKYIQKDLR 271

Query: 242 LALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEA 283
           LA+ALGD      P+AAAANE +K+A++L   D D SAV  A
Sbjct: 272 LAIALGDAVNHPTPMAAAANEVYKRAKALDQSDNDMSAVYRA 313


>5XVH-A nrPDB
          Length = 306

 Score =  162 bits (409), Expect = 2e-40,   Method: Compositional matrix adjust.
 Identities = 99/280 (35%), Positives = 142/280 (50%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60
           M VGF+GLGIMG  M+ +LLK GF   V+NRT  K     E G  V ESPA++ K+    
Sbjct: 21  MRVGFIGLGIMGGPMATHLLKAGFLAAVYNRTREKTKPFAEAGVYVAESPADLAKRVDVV 80

Query: 61  IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120
           I M+SD      V+F   GV+E    G   +DMST   + + K  E +   G  F++ PV
Sbjct: 81  IVMVSDAPDVEQVLFGPSGVVEGARPGLIVVDMSTNSPDWARKFAERLAQYGIEFLDAPV 140

Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 180
           +G +K A +G L I+  G + LF   +P F  +G+   Y+G VG G  MKL+  +++   
Sbjct: 141 TGGQKGAIEGTLTIMVGGKEELFHRLLPIFKAMGRDIVYMGPVGYGQAMKLVNQVVVALN 200

Query: 181 MNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDM 240
             A  EGL LA   GL  D + ++L  GA  +   +   P + K    P F  +H +KD+
Sbjct: 201 TVAMVEGLKLAKALGLDMDKVAEVLTRGAARSGAIELYLPKLLKGDLSPGFKAEHLKKDL 260

Query: 241 RLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAV 280
              L    +  V +P A  A E ++K    G G L   A+
Sbjct: 261 GYVLEEARKRGVKLPGAELAYELYRKMVEDGAGSLGIHAL 300


>3CKY-A nrPDB
          Length = 301

 Score =  144 bits (364), Expect = 3e-35,   Method: Compositional matrix adjust.
 Identities = 95/283 (33%), Positives = 151/283 (53%), Gaps = 1/283 (0%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60
           +++GF+GLG MGK M++NLLK G  V  ++   +    +V  GA  CE+  +V       
Sbjct: 5   IKIGFIGLGAMGKPMAINLLKEGVTVYAFDLMEANVAAVVAQGAQACENNQKVAAASDII 64

Query: 61  IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120
              L +     +V+   GGVL     G   +DMS+V   ++LK+ +    KG  +V+ PV
Sbjct: 65  FTSLPNAGIVETVMNGPGGVLSACKAGTVIVDMSSVSPSSTLKMAKVAAEKGIDYVDAPV 124

Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 180
           SG  K AE G L I+    +A+FE+  P   V+GK  +++G  G G  +K++ N+++G  
Sbjct: 125 SGGTKGAEAGTLTIMVGASEAVFEKIQPVLSVIGKDIYHVGDTGAGDAVKIVNNLLLGCN 184

Query: 181 MNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSS-YPPAFPLKHQQKD 239
           M + +E LVL  K GL  +T+ +I+   +  +   + K      S  +   F +  Q KD
Sbjct: 185 MASLAEALVLGVKCGLKPETMQEIIGKSSGRSYAMEAKMEKFIMSGDFAGGFAMDLQHKD 244

Query: 240 MRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIE 282
           + LAL  G E  V +P+ A A + F+  R++GLG  D SAVI+
Sbjct: 245 LGLALEAGKEGNVPLPMTAMATQIFEGGRAMGLGREDMSAVIK 287


>1VPD-A nrPDB
          Length = 299

 Score =  138 bits (348), Expect = 2e-33,   Method: Compositional matrix adjust.
 Identities = 86/280 (30%), Positives = 140/280 (50%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60
           M+VGF+GLGIMGK MS NLLK G+ + V +R      +++  GA    +   + ++C   
Sbjct: 6   MKVGFIGLGIMGKPMSKNLLKAGYSLVVSDRNPEAIADVIAAGAETASTAKAIAEQCDVI 65

Query: 61  IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120
           I ML +      V   + G++E    G   IDMS++    S +I++A+  KG   ++ PV
Sbjct: 66  ITMLPNSPHVKEVALGENGIIEGAKPGTVLIDMSSIAPLASREISDALKAKGVEMLDAPV 125

Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 180
           SG +  A DG L ++  GDKA+F++       +     + G +G G   KL   +I+   
Sbjct: 126 SGGEPKAIDGTLSVMVGGDKAIFDKYYDLMKAMAGSVVHTGDIGAGNVTKLANQVIVALN 185

Query: 181 MNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDM 240
           + A SE L LA K+G++ D +   +  G   + +   K P +   ++ P F +    KD+
Sbjct: 186 IAAMSEALTLATKAGVNPDLVYQAIRGGLAGSTVLDAKAPMVMDRNFKPGFRIDLHIKDL 245

Query: 241 RLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAV 280
             AL         +P+ AA  E  +  R+ G G+ D SA+
Sbjct: 246 ANALDTSHGVGAQLPLTAAVMEMMQALRADGHGNDDHSAL 285


>1YB4-A nrPDB
          Length = 295

 Score =  131 bits (329), Expect = 3e-31,   Method: Compositional matrix adjust.
 Identities = 85/287 (29%), Positives = 146/287 (50%), Gaps = 3/287 (1%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSK-CDELVEHGASVCESPAEVIKKCKY 59
           M++GF+GLGIMG  M++NL + G ++ V   T+    DEL+  GA   E+  +V +    
Sbjct: 4   MKLGFIGLGIMGSPMAINLARAGHQLHVT--TIGPVADELLSLGAVNVETARQVTEFADI 61

Query: 60  TIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGP 119
              M+ D      V+F + G  +   +GK  +DMS++    + +  + +   G  +++ P
Sbjct: 62  IFIMVPDTPQVEDVLFGEHGCAKTSLQGKTIVDMSSISPIETKRFAQRVNEMGADYLDAP 121

Query: 120 VSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGS 179
           VSG +  A +G L I+  G++ +F+   P FD+LGK    +G  G+G   K+   +I+  
Sbjct: 122 VSGGEIGAREGTLSIMVGGEQKVFDRVKPLFDILGKNITLVGGNGDGQTCKVANQIIVAL 181

Query: 180 MMNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKD 239
            + A SE LV A K+G     +   L  G  ++ + +  G  M   ++ P F +   QKD
Sbjct: 182 NIEAVSEALVFASKAGADPVRVRQALMGGFASSRILEVHGERMINRTFEPGFKIALHQKD 241

Query: 240 MRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVKF 286
           + LAL      A+++P  A   E F    + G   LD SA+++A++ 
Sbjct: 242 LNLALQSAKALALNLPNTATCQELFNTCAANGGSQLDHSAMVQALEL 288


>5JE8-A nrPDB
          Length = 302

 Score =  120 bits (300), Expect = 8e-28,   Method: Compositional matrix adjust.
 Identities = 85/287 (29%), Positives = 146/287 (50%), Gaps = 6/287 (2%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDE--LVEHGASVCESPAEVIKKCKY 59
           ++GF+GLG MG  MS NL+K+G+  TV+   L+K  E    + G  +  S +++ + C  
Sbjct: 9   KIGFIGLGNMGLPMSKNLVKSGY--TVYGVDLNKEAEASFEKEGGIIGLSISKLAETCDV 66

Query: 60  TIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGP 119
               L  P A  +V F   G+ E       +ID STV  + + ++ EA   K   F+  P
Sbjct: 67  VFTSLPSPRAVEAVYFGAEGLFENGHSNVVFIDTSTVSPQLNKQLEEAAKEKKVDFLAAP 126

Query: 120 VSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLG-QVGNGAKMKLIVNMIMG 178
           VSG    AE+  L  +  G K ++E++     VLG   F++  Q+ +G  +KLI N+++G
Sbjct: 127 VSGGVIGAENRTLTFMVGGSKDVYEKTESIMGVLGANIFHVSEQIDSGTTVKLINNLLIG 186

Query: 179 SMMNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPS-MNKSSYPPAFPLKHQQ 237
                 SE L LA K+ +  D + DIL++    + +++    S +   +Y P F +   +
Sbjct: 187 FYTAGVSEALTLAKKNNMDLDKMFDILNVSYGQSRIYERNYKSFIAPENYEPGFTVNLLK 246

Query: 238 KDMRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAV 284
           KD+  A+ L  E+ + +PV+      + +A   G G+ D +A+ + V
Sbjct: 247 KDLGFAVDLAKESELHLPVSEMLLNVYDEASQAGYGENDMAALYKKV 293


>4DLL-A nrPDB
          Length = 320

 Score =  117 bits (294), Expect = 5e-27,   Method: Compositional matrix adjust.
 Identities = 82/280 (29%), Positives = 132/280 (47%), Gaps = 2/280 (0%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61
           ++ FLG G MG  M+  L + G+ + VWNRT ++   L   GA++ E      +     +
Sbjct: 33  KITFLGTGSMGLPMARRLCEAGYALQVWNRTPARAASLAALGATIHEQARAAARDADIVV 92

Query: 62  AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121
           +ML +      V+F +G V   +  G  ++DM+++    +      +   G   ++ PVS
Sbjct: 93  SMLENGAVVQDVLFAQG-VAAAMKPGSLFLDMASITPREARDHAARLGALGIAHLDTPVS 151

Query: 122 GSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMM 181
           G    AE G L+I+A G  A FE S+P   V G R+ ++G  G+G   KL   MI+G  +
Sbjct: 152 GGTVGAEQGTLVIMAGGKPADFERSLPLLKVFG-RATHVGPHGSGQLTKLANQMIVGITI 210

Query: 182 NAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDMR 241
            A +E L+ A K G     + + +  G   + + +  G  M +  + P   L  Q KDMR
Sbjct: 211 GAVAEALLFATKGGADMAKVKEAITGGFADSRVLQLHGQRMVERDFAPRARLSIQLKDMR 270

Query: 242 LALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVI 281
            ALA   E     P+     + + +    GL DLD S + 
Sbjct: 271 NALATAQEIGFDAPITGLFEQLYAEGVEHGLTDLDQSGLF 310


>2GF2-A nrPDB
          Length = 296

 Score =  109 bits (273), Expect = 1e-24,   Method: Compositional matrix adjust.
 Identities = 84/298 (28%), Positives = 135/298 (45%), Gaps = 14/298 (4%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60
           M VGF+GLG MG  M+ NL+K+G+ + +++     C E  + G  V  SPA+V +K    
Sbjct: 1   MPVGFIGLGNMGNPMAKNLMKHGYPLIIYDVFPDACKEFQDAGEQVVSSPADVAEKADRI 60

Query: 61  IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120
           I ML     A+       G+L+++ +G   ID ST+D   S ++ + +   G  F++ PV
Sbjct: 61  ITMLPTSINAIEAYSGANGILKKVKKGSLLIDSSTIDPAVSKELAKEVEKMGAVFMDAPV 120

Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 180
           SG    A  G L  +  G +  F  +      +G    Y G VG G   K+  NM++   
Sbjct: 121 SGGVGAARSGNLTFMVGGVEDEFAAAQELLGCMGSNVVYCGAVGTGQAAKICNNMLLAIS 180

Query: 181 MNAFSEGLVLADKSGLSSDTLLDILDLGA-------MTNPM--FKGKGPSMNKSSYPPAF 231
           M   +E + L  + GL    L  IL++ +         NP+       PS N  +Y   F
Sbjct: 181 MIGTAEAMNLGIRLGLDPKLLAKILNMSSGRCWSSDTYNPVPGVMDGVPSAN--NYQGGF 238

Query: 232 PLKHQQKDMRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVKFSRE 289
                 KD+ LA          + + + A++ ++   + G    DFS+V +   F RE
Sbjct: 239 GTTLMAKDLGLAQDSATSTKSPILLGSLAHQIYRMMCAKGYSKKDFSSVFQ---FLRE 293


>4GBJ-A nrPDB
          Length = 297

 Score = 95.1 bits (235), Expect = 3e-20,   Method: Compositional matrix adjust.
 Identities = 73/281 (25%), Positives = 132/281 (46%), Gaps = 4/281 (1%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61
           ++ FLGLG +G  ++  LL+ G+++ VWNRT SK + L + GA+V E+  + I       
Sbjct: 7   KIAFLGLGNLGTPIAEILLEAGYELVVWNRTASKAEPLTKLGATVVENAIDAITPGGIVF 66

Query: 62  AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121
           ++L+D  AA+  +F    ++E++ +   ++ MST+  ETS ++ +     G  +V  P+ 
Sbjct: 67  SVLADD-AAVEELFSM-ELVEKLGKDGVHVSMSTISPETSRQLAQVHEWYGAHYVGAPIF 124

Query: 122 GSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLG-QVGNGAKMKLIVNMIMGSM 180
              +        I  +G+    E   P  +   K  F  G   G    +KL  N ++   
Sbjct: 125 ARPEAVRAKVGNICLSGNAGAKERIKPIVENFVKGVFDFGDDPGAANVIKLAGNFMIACS 184

Query: 181 MNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPP-AFPLKHQQKD 239
           +    E   +A+K+G+S  ++ ++L       P+F+  G  +  ++Y P AF      KD
Sbjct: 185 LEMMGEAFTMAEKNGISRQSIYEMLTSTLFAAPIFQNYGKLVASNTYEPVAFRFPLGLKD 244

Query: 240 MRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAV 280
           + L L    +    MP A      F    + G  +LD+ A+
Sbjct: 245 INLTLQTASDVNAPMPFADIIRNRFISGLAKGRENLDWGAL 285


>5Y8M-A nrPDB
          Length = 295

 Score = 89.0 bits (219), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 78/290 (26%), Positives = 123/290 (42%), Gaps = 11/290 (3%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62
           + FLGLG MG  MS NL+  G  V  ++   +       HG +V  S  E + +    I 
Sbjct: 5   IAFLGLGNMGAPMSANLVGAGHVVRGFDPAPTAASGAAAHGVAVFRSAPEAVAEADVVIT 64

Query: 63  MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSG 122
           ML           D   VL        +ID ST+    + +++      G   ++ PVSG
Sbjct: 65  MLPTGEVVRRCYTD---VLAAARPATLFIDSSTISVTDAREVHALAESHGMLQLDAPVSG 121

Query: 123 SKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMMN 182
             K A    L  +  GD++    + P  + +  +  + G  G G   K+  NM++     
Sbjct: 122 GVKGAAAATLAFMVGGDESTLRRARPVLEPMAGKIIHCGAAGAGQAAKVCNNMVLAVQQI 181

Query: 183 AFSEGLVLADKSGLSSDTLLDILD------LGAMTNPMFKGKGP-SMNKSSYPPAFPLKH 235
           A +E  VLA+K GLS+ +L D++           TN    G  P S   + + P F    
Sbjct: 182 AIAEAFVLAEKLGLSAQSLFDVITGATGNCWAVHTNCPVPGPVPTSPANNDFKPGFSTAL 241

Query: 236 QQKDMRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVK 285
             KD+ LA+        + P+ + A + + K  +    DLDFSAVI  ++
Sbjct: 242 MNKDLGLAMDAVAATGATAPLGSHAADIYAK-FAADHADLDFSAVIHTLR 290


>2CVZ-A nrPDB
          Length = 289

 Score = 89.0 bits (219), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 73/272 (26%), Positives = 125/272 (45%), Gaps = 8/272 (2%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61
           +V F+GLG MG  M+ +L +  F   VWNRT  K     E   S    P E + + +   
Sbjct: 3   KVAFIGLGAMGYPMAGHLARR-FPTLVWNRTFEKALRHQEEFGSEA-VPLERVAEARVIF 60

Query: 62  AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121
             L        V      +   + EG  ++D ++ + E S ++ E +  KG  +++ PVS
Sbjct: 61  TCLPTTREVYEVA---EALYPYLREGTYWVDATSGEPEASRRLAERLREKGVTYLDAPVS 117

Query: 122 GSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMM 181
           G    AE G L ++  G +   E   P F    K+  ++G VG G  +K I N ++   +
Sbjct: 118 GGTSGAEAGTLTVMLGGPEEAVERVRP-FLAYAKKVVHVGPVGAGHAVKAINNALLAVNL 176

Query: 182 NAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPS-MNKSSYPPAFPLKHQQKDM 240
            A  EGL+   K G+S++  L++++  +  +   +   P  +   ++P  F L    KD+
Sbjct: 177 WAAGEGLLALVKQGVSAEKALEVINASSGRSNATENLIPQRVLTRAFPKTFALGLLVKDL 236

Query: 241 RLALALGDENAVSMPVAAAANEAFKKA-RSLG 271
            +A+ + D      P+   A E ++ A R LG
Sbjct: 237 GIAMGVLDGEKAPSPLLRLAREVYEMAKRELG 268


>3Q3C-A nrPDB
          Length = 299

 Score = 85.9 bits (211), Expect = 2e-17,   Method: Compositional matrix adjust.
 Identities = 61/204 (29%), Positives = 101/204 (49%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61
           ++ F+GLG MG  M+ NLLK G+ + V++   S  D LV  GAS   S  + ++     I
Sbjct: 4   QIAFIGLGHMGAPMATNLLKAGYLLNVFDLVQSAVDGLVAAGASAARSARDAVQGADVVI 63

Query: 62  AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121
           +ML        +  D  G+L  I  G   ++ ST+   ++ KI+ A   +G   ++ PVS
Sbjct: 64  SMLPASQHVEGLYLDDDGLLAHIAPGTLVLECSTIAPTSARKIHAAARERGLAMLDAPVS 123

Query: 122 GSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMM 181
           G    A  G L  +  GD    E++ P F+ +G+  F+ G  G G   K+  N ++  +M
Sbjct: 124 GGTAGAAAGTLTFMVGGDAEALEKARPLFEAMGRNIFHAGPDGAGQVAKVCNNQLLAVLM 183

Query: 182 NAFSEGLVLADKSGLSSDTLLDIL 205
              +E + L   +GL +  L +I+
Sbjct: 184 IGTAEAMALGVANGLEAKVLAEIM 207


>4D3S-A nrPDB
          Length = 293

 Score = 80.9 bits (198), Expect = 6e-16,   Method: Compositional matrix adjust.
 Identities = 69/270 (25%), Positives = 117/270 (43%), Gaps = 23/270 (8%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62
           V  +GLG MG+AM+  LL+ G+++TVWNRT +K + L E GA+V +SPAE ++     + 
Sbjct: 11  VTLIGLGPMGQAMAGALLEAGYELTVWNRTKAKAEALAERGAAVADSPAEALRAGGPVLL 70

Query: 63  MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSG 122
            L++      V+  +G   E   +G+  +++ +     S        G G R+V G V  
Sbjct: 71  SLTEHAVMYRVL--EGA--ESDLKGRTILNLGSDTPAASRAAAAWAEGHGARYVTGGVMS 126

Query: 123 SKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMMN 182
                    +    +GD+A FEE+    +VL    F     G       I+  +  + M 
Sbjct: 127 PAPGIGSSSVFSFYSGDRAAFEENKALLEVLTATDFRGEDPGLAQVYYQILLDLFWTTMT 186

Query: 183 AFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDMRL 242
            +   L +A   G+   T+   L  G      F+G   ++ +  +P              
Sbjct: 187 GYLHALAVARAEGVPVGTITPYLIEGNDMAMFFEGTSAAVAEGRFP-------------- 232

Query: 243 ALALGDENAVSMPVAAAANEAFKKARSLGL 272
               GDE+ +SM  AA+     + +R  G+
Sbjct: 233 ----GDEDRISMD-AASMEHVVQTSRDAGV 257


>4D3F-A nrPDB
          Length = 310

 Score = 79.7 bits (195), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 76/299 (25%), Positives = 130/299 (43%), Gaps = 30/299 (10%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62
           V  +GLG MG+AM+   L+ G+ VTVWNRT SK D+LV  GA    +  E +   +  I 
Sbjct: 24  VTVIGLGPMGQAMADVFLEYGYSVTVWNRTSSKADQLVAKGAIRVSTVNEALAANELVIL 83

Query: 63  MLSDPCAALSVVFDKGGVLEQICE---GKGYIDMSTVDAETSLKINEAITGKGGRFVEGP 119
            L+D     S       +LE + E   GK  +++S+   E + K  + +  +G R + G 
Sbjct: 84  SLTDYNVMYS-------ILEPVSENLFGKVLVNLSSDTPEKARKAAKWLEDRGARHITGG 136

Query: 120 VSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNM-IMG 178
           V          +     +GD+ +FE      +VL   S Y G+    A +   + M I  
Sbjct: 137 VQVPPSGIGKSESYTYYSGDRVVFEAHRETLEVL-TSSDYRGEDPGLAMLYYQIQMDIFW 195

Query: 179 SMMNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMF-KGKGPSMNKSSYPPAFPLKHQQ 237
           + M ++   L +A+ +G++++  L        + P F +   P +++  +P         
Sbjct: 196 TAMLSYLHALAIANANGITAEQFLPYASAMMSSLPKFVEFYTPRLDEGEHPGDVD----- 250

Query: 238 KDMRLALALG---------DENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVKFS 287
              RLA+ L           E  + + + A   E F++    G     F+++IE  K S
Sbjct: 251 ---RLAMGLASVEHVVHTTQEAGIDIALPATVLEVFRRGMKTGHASDSFTSLIEIFKNS 306


>3G0O-A nrPDB
          Length = 303

 Score = 78.2 bits (191), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 71/285 (24%), Positives = 127/285 (44%), Gaps = 6/285 (2%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLS--KCDELVEHGA-SVCESPAEVIKKCK 58
            VG +GLG MG   + + L+ G   + W   L+   C  L+  GA     S  E      
Sbjct: 9   HVGIVGLGSMGMGAARSCLRAGL--STWGADLNPQACANLLAEGACGAAASAREFAGVVD 66

Query: 59  YTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEG 118
             + ++ +      V+F + GV   +  G   +  ST+ +  + +I  A+T      ++ 
Sbjct: 67  ALVILVVNAAQVRQVLFGEDGVAHLMKPGSAVMVSSTISSADAQEIAAALTALNLNMLDA 126

Query: 119 PVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQV-GNGAKMKLIVNMIM 177
           PVSG    A  G++ ++A+G +A F    P  D +    + +    G G+ +K+I  ++ 
Sbjct: 127 PVSGGAVKAAQGEMTVMASGSEAAFTRLKPVLDAVASNVYRISDTPGAGSTVKIIHQLLA 186

Query: 178 GSMMNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQ 237
           G  + A +E + LA ++G+  D + D++   A  + MF+ +   +    Y P   +    
Sbjct: 187 GVHIAAAAEAMALAARAGIPLDVMYDVVTHAAGNSWMFENRMQHVVDGDYTPRSAVDIFV 246

Query: 238 KDMRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIE 282
           KD+ L           +P+A+ A   F  A + G G  D SAVI+
Sbjct: 247 KDLGLVADTAKALRFPLPLASTALNMFTSASNAGYGKEDDSAVIK 291


>3QHA-A nrPDB
          Length = 296

 Score = 76.6 bits (187), Expect = 1e-14,   Method: Compositional matrix adjust.
 Identities = 76/275 (27%), Positives = 126/275 (45%), Gaps = 18/275 (6%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60
           +++G++GLG MG  M+  + +    VTV++  +     L E GA++ +S A+V       
Sbjct: 16  LKLGYIGLGNMGAPMATRMTEWPGGVTVYDIRIEAMTPLAEAGATLADSVADVAAADLIH 75

Query: 61  IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120
           I +L D      VV +  G       G      ST+   T++++   +  +    V+ PV
Sbjct: 76  ITVLDD-AQVREVVGELAG---HAKPGTVIAIHSTISDTTAVELARDLKARDIHIVDAPV 131

Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 180
           SG    A  G+L  +   D+ ++E   PAF        + G+ G G +MKL  NM+  + 
Sbjct: 132 SGGAAAAARGELATMVGADREVYERIKPAFKHWAAVVIHAGEPGAGTRMKLARNMLTFTS 191

Query: 181 MNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSY----PPAF---PL 233
             A  E + LA+ +GL    L  ++     T+ +  G G  M + +     P  F   P 
Sbjct: 192 YAAACEAMKLAEAAGLDLQALGRVVR---HTDALTGGPGAIMVRDNMKDLEPDNFLYQPF 248

Query: 234 KHQ----QKDMRLALALGDENAVSMPVAAAANEAF 264
            H     +KD+ LALALG+  +V +P+A  A E  
Sbjct: 249 LHTRGLGEKDLSLALALGEAVSVDLPLARLAYEGL 283


>4OQZ-A nrPDB
          Length = 289

 Score = 73.9 bits (180), Expect = 7e-14,   Method: Compositional matrix adjust.
 Identities = 71/294 (24%), Positives = 131/294 (44%), Gaps = 23/294 (7%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62
           V  +GLG MG+AM+   L  G++VT+WNRT S+ D LV  GA +  +P + +   +  I 
Sbjct: 5   VTVIGLGPMGQAMAAAYLDRGYEVTLWNRTASRADALVARGAKLAATPEQALSANELVIL 64

Query: 63  MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSG 122
            L D  A   V+  +G   E+   G+  +++S+   E +      +   GG  + G V  
Sbjct: 65  SLIDYDAMYGVL--EGA--EEAVAGRVLVNLSSDTPEKARAAARRVAELGGTHLTGGVLS 120

Query: 123 SKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIM-GSMM 181
                    +    +G +A +++   A +V+  ++ Y G+    A +   +NM++    M
Sbjct: 121 PPPGIGSPDMSTFYSGPRAAYDQHRAALEVITGKTDYRGEDPGLAALMYQLNMVVFWPAM 180

Query: 182 NAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDM- 240
            ++ + + LAD  GL++       D+    +  F G G  ++   Y       +   D+ 
Sbjct: 181 LSYWQAVALADAHGLTA------ADIAPYVSENFAGMGQFID--FYAARIDAGNHAGDVD 232

Query: 241 RLALALGD---------ENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVK 285
           RL++ +           ++ V      A  +AF +    G G   FS+VI+ +K
Sbjct: 233 RLSMGVASMEHVVHTNADSGVDTAFPRAVLDAFHRGADAGFGADSFSSVIKLMK 286


>5OCM-A nrPDB
          Length = 291

 Score = 72.8 bits (177), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 51/190 (26%), Positives = 90/190 (47%), Gaps = 5/190 (2%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61
           +V  LGLG+MG+A++   LK+G   TVWNR+  K  +L E GA +  S  +  +     +
Sbjct: 5   DVTVLGLGLMGQALAGAFLKDGHATTVWNRSEGKAGQLAEQGAVLASSARDAAEASPLVV 64

Query: 62  AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121
             +SD  A  +V+   G VL     G+  +++++  +E +    E    +G  +++G + 
Sbjct: 65  VCVSDHAAVRAVLDPLGDVL----AGRVLVNLTSGTSEQARATAEWAAERGITYLDGAIM 120

Query: 122 GSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLG-QVGNGAKMKLIVNMIMGSM 180
              +        +L +G +A +E   P    LG  + YLG   G  +   + +  IM   
Sbjct: 121 AIPQVVGTADAFLLYSGPEAAYEAHEPTLRSLGAGTTYLGADHGLSSLYDVALLGIMWGT 180

Query: 181 MNAFSEGLVL 190
           +N+F  G  L
Sbjct: 181 LNSFLHGAAL 190


>3ZHB-A nrPDB
          Length = 309

 Score = 72.8 bits (177), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 55/228 (24%), Positives = 102/228 (44%), Gaps = 5/228 (2%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62
           V  +GLG+MG+A++   L  G   TVWNRT +K + LV  GA    S AE +      + 
Sbjct: 22  VTVIGLGLMGQALAGAFLGAGHPTTVWNRTAAKAEPLVARGAKSAGSVAEAVAASPLVVV 81

Query: 63  MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSG 122
            +SD  A  +++    G   Q   G+  +++++  +  + +      G+G  +++G +  
Sbjct: 82  CVSDYDAVHALLDPLDGTALQ---GRTLVNLTSGTSAQARERAAWADGRGADYLDGAILA 138

Query: 123 SKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMI-MGSMM 181
                     ++L +G ++ F+    A   LG  + YLG     A +     ++ M S++
Sbjct: 139 GPAAIGTADAVVLLSGPRSAFDPHASALGGLGAGTTYLGADHGLASLYDAAGLVMMWSIL 198

Query: 182 NAFSEGLVLADKSGLSSDTLLDILDLGAMT-NPMFKGKGPSMNKSSYP 228
           N F +G  L   +G+ + T    +  G  T      G    ++  +YP
Sbjct: 199 NGFLQGAALLGTAGVDATTFAPFITQGIGTVADWLPGYARQIDDGAYP 246


>5U5G-A nrPDB
          Length = 295

 Score = 67.8 bits (164), Expect = 6e-12,   Method: Compositional matrix adjust.
 Identities = 58/221 (26%), Positives = 99/221 (44%), Gaps = 12/221 (5%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCK--YT 60
           VGF+GLG MG+A+   LL +   V V NR+  K D+L+  GA        + +  +  + 
Sbjct: 5   VGFIGLGRMGQAICRRLLASQMPVHVHNRSREKADDLIRQGAVWAPDIVALTRAARVLFV 64

Query: 61  IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120
               S+         D+G +L  +  G   +D+ST+  ET+  ++ A   +G  ++E PV
Sbjct: 65  CTAGSEAVQDFYHAPDRG-LLACLEVGDIVVDLSTIAPETAEGLHAAFAQQGADYIECPV 123

Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 180
           SG  + A  G L  + +G    +    P  +V      Y+ + G   ++K+         
Sbjct: 124 SGGVEGALAGILSAIVSGRPEAYGLIRPLLEVFCATVTYVPEPGKAQRLKI--------- 174

Query: 181 MNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPS 221
           +N  +E + LA    + S  L   LDL +M +     +G S
Sbjct: 175 LNNLAESINLAGAIEVISQGLSQGLDLKSMADVFTSCRGRS 215


>5G6R-A nrPDB
          Length = 295

 Score = 66.2 bits (160), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 78/299 (26%), Positives = 127/299 (42%), Gaps = 22/299 (7%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61
            +G  GLG MG A++   L++G+K +VWNRT +K   LVE GA +  + +E +      I
Sbjct: 4   HIGIFGLGAMGTALAAKYLEHGYKTSVWNRTTAKAIPLVEQGAKLASTISEGVNANDLII 63

Query: 62  AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121
             L +      VV D      Q    K  ++++      + K+ + +T  G R++ G + 
Sbjct: 64  ICLLNN----QVVEDALRDALQTLPSKTIVNLTNGTPNQARKLADFVTSHGARYIHGGIM 119

Query: 122 GSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQ-VGNGAKMKLIVNMIMGSM 180
                      ++L +G+     +SI +   L   S YLG   G+ +   L +   M  +
Sbjct: 120 AVPTMIGSPHAVLLYSGESLELFQSIESHLSLLGMSKYLGTDAGSASLHDLALLSGMYGL 179

Query: 181 MNAFSEGLVLADKSGLSSDT----LLDILD--LGAMTNPMFKGKGPSMNKSSYPPAFPLK 234
            + F   + L  KSG  + T    LL +L   L AMT     G   S+ K      +  +
Sbjct: 180 FSGFLHAVALI-KSGQDTSTTATGLLPLLTPWLSAMT-----GYLSSIAKQIDDGDYATQ 233

Query: 235 HQQKDMRLA-----LALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVKFSR 288
                M+LA     +  G+E  VS  +        ++A   G G  D SA+IE  K  +
Sbjct: 234 GSNLGMQLAGVENIIRAGEEQRVSSQMILPIKALIEQAVGEGHGGEDLSALIEYFKVGK 292


>4OQY-A nrPDB
          Length = 290

 Score = 65.1 bits (157), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 72/286 (25%), Positives = 120/286 (41%), Gaps = 8/286 (2%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62
           V  +GLG MG+AM    L NG +VTVWNRT SK + LV  GA +  +  + +   +  + 
Sbjct: 6   VTVIGLGPMGQAMVNTFLDNGHEVTVWNRTASKAEALVARGAVLAPTVEDALSANELIVL 65

Query: 63  MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSG 122
            L+D  A  +++    G L     GK   ++S+   + + +  +     G + + G V  
Sbjct: 66  SLTDYDAVYAILEPVTGSL----SGKVIANLSSDTPDKAREAAKWAAKHGAKHLTGGVQV 121

Query: 123 SKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNM-IMGSMM 181
                   +     +G K +F+       VL   + Y G+    A M     M I  + M
Sbjct: 122 PPPLIGKPESSTYYSGPKDVFDAHEDTLKVL-TNADYRGEDAGLAAMYYQAQMTIFWTTM 180

Query: 182 NAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMF-KGKGPSMNKSSYPPAFP-LKHQQKD 239
            ++ + L L   +G+S+  LL    +     P F +     ++ + YP     L      
Sbjct: 181 LSYYQTLALGQANGVSAKELLPYATMMTSMMPHFLELYAQHVDSADYPGDVDRLAMGAAS 240

Query: 240 MRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVK 285
           +   L    +  VS  + AA  E FK     G  +  FS++IE +K
Sbjct: 241 VDHVLHTHQDAGVSTVLPAAVAEIFKAGMEKGFAENSFSSLIEVLK 286


>5A9T-A nrPDB
          Length = 290

 Score = 63.5 bits (153), Expect = 1e-10,   Method: Compositional matrix adjust.
 Identities = 71/295 (24%), Positives = 125/295 (42%), Gaps = 26/295 (8%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60
           + V   GLG MG A++  LL  G  VTVWNR+  K   LV  GA   +   + +   +  
Sbjct: 6   LPVTVAGLGPMGSALAAALLDRGHDVTVWNRSPGKAAPLVAKGARQADDIVDAVSASRLL 65

Query: 61  IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITG---KGGRFVE 117
           +  L+D  A  S +    G   +   G+  +++   ++ T  + NEA+      G  +++
Sbjct: 66  VVCLADYDALYSAL----GPAREALRGRVVVNL---NSGTPKEANEALRWAERHGTGYLD 118

Query: 118 GPVSGSKKPAEDGQ--LIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNM 175
           G +     PA  G    + L +G   +FEE       LG        +G  A + ++ N 
Sbjct: 119 GAI--MVPPAMVGHPGSVFLYSGSAEVFEEYKETLAGLGDPV----HLGTEAGLAVLYNT 172

Query: 176 IMGSM----MNAFSEGLVLADKSGLSSDTLLDI-LD--LGAMTNPMFKGKGPSMNKSSYP 228
            + SM    MN F     L   +G+ +     + +D  L A+   + K + P++++  YP
Sbjct: 173 ALLSMMYSSMNGFLHAAALVGSAGVPAAEFTKLAVDWFLPAVIGQIIKAEAPTIDEGVYP 232

Query: 229 -PAFPLKHQQKDMRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIE 282
             A  L+     ++  +    E  V   +     E   +A + G G+  + +VIE
Sbjct: 233 GDAGSLEMNVTTLKHIIGTSQEQGVDTEIPVRNKELLDRAVAAGFGESSYYSVIE 287


>3L6D-A nrPDB
          Length = 306

 Score = 58.5 bits (140), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 72/301 (23%), Positives = 122/301 (40%), Gaps = 26/301 (8%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60
            +V  +GLG MG  M+  LLK G +V +WNR+  K   LV  GA +CES    +     T
Sbjct: 10  FDVSVIGLGAMGTIMAQVLLKQGKRVAIWNRSPGKAAALVAAGAHLCESVKAALSASPAT 69

Query: 61  IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120
           I +L D  A   V+   G  + +    +  +D +T   +  L +   +   GG +V+G +
Sbjct: 70  IFVLLDNHATHEVLGMPG--VARALAHRTIVDYTTNAQDEGLALQGLVNQAGGHYVKGMI 127

Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 180
               +     +   +  GD+  FE+     + L   + +L           +++    + 
Sbjct: 128 VAYPRNVGHRESHSIHTGDREAFEQHRALLEGLAGHTVFLPW-DEALAFATVLHAHAFAA 186

Query: 181 MNAFSEGLVLADKSGL----SSDTLL--------DILDLGAMTNPMFKGKGPSMNKSSYP 228
           M  F E +   D+ GL    ++  LL        D L+           KG       + 
Sbjct: 187 MVTFFEAVGAGDRFGLPVSKTARLLLETSRFFVADALEEAVRRLETQDFKGDQARLDVHA 246

Query: 229 PAFPLKHQQKDMRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVKFSR 288
            AF          +A +L     V  PV  A  +  ++A ++G GD D +A  ++  F+R
Sbjct: 247 DAFA--------HIAQSL-HAQGVWTPVFDAVCQVVQRAAAMGYGDQDIAATTKS--FAR 295

Query: 289 E 289
           E
Sbjct: 296 E 296


>2W8Z-A nrPDB
          Length = 470

 Score = 50.4 bits (119), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 48/202 (23%), Positives = 86/202 (42%), Gaps = 17/202 (8%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEH-------GASVCESPAEVI 54
           ++G +GL +MGK +++N+   G+ V V+NR   K DE ++        G    E     +
Sbjct: 6   QIGVIGLAVMGKNLALNIESKGYSVAVYNRLREKTDEFLQEAKGKNIVGTYSIEEFVNAL 65

Query: 55  KKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGR 114
           +K +  + M+       + +      LE+   G   ID      + + + N+ +   G  
Sbjct: 66  EKPRKILLMVKAGAPTDATIEQLKPHLEK---GDIVIDGGNTYFKDTQRRNKELAELGIH 122

Query: 115 FVEGPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKR------SFYLGQVGNGAK 168
           F+   VSG ++ A  G   I+  G K   E   P F+ +  +      + Y+G  G G  
Sbjct: 123 FIGTGVSGGEEGALKGPS-IMPGGQKEAHELVRPIFEAIAAKVDGEPCTTYIGPDGAGHY 181

Query: 169 MKLIVNMIMGSMMNAFSEGLVL 190
           +K++ N I    M   +E   L
Sbjct: 182 VKMVHNGIEYGDMQLIAEAYFL 203


>6EOI-A nrPDB
          Length = 298

 Score = 49.3 bits (116), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 34/116 (29%), Positives = 51/116 (43%), Gaps = 4/116 (3%)

Query: 5   FLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIAML 64
             GLG MG AM+   LK G   TVWNRT +K + LVE GA +  +    I      I  L
Sbjct: 12  IFGLGAMGTAMATQFLKQGHTPTVWNRTAAKANPLVEQGAHLAATIPAAIAASPLLIFCL 71

Query: 65  SDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120
            D  AA+      G        GK  ++++      + ++    + +G R+  G +
Sbjct: 72  LD-NAAVEQTLAAG---PPSLAGKTILNLTNGTPSQARRLATLASARGARYFHGGI 123


>2ZYA-A nrPDB
          Length = 480

 Score = 48.9 bits (115), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 49/211 (23%), Positives = 93/211 (44%), Gaps = 19/211 (9%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60
            ++G +G+ +MG+ +++N+   G+ V+++NR+  K +E++         P   +K+    
Sbjct: 16  QQIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVIAENPGKKLVPYYTVKEF--- 72

Query: 61  IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMS--TVDA-----ETSLKINEAITGKGG 113
           +  L  P   L +V    G    I   K Y+D     +D      + +++ N  ++ +G 
Sbjct: 73  VESLETPRRILLMVKAGAGTDAAIDSLKPYLDKGDIIIDGGNTFFQDTIRRNRELSAEGF 132

Query: 114 RFVEGPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRS-------FYLGQVGNG 166
            F+   VSG ++ A  G   I+  G K  +E   P    +   +        Y+G  G G
Sbjct: 133 NFIGTGVSGGEEGALKGPS-IMPGGQKEAYELVAPILTKIAAVAEDGEPCVTYIGADGAG 191

Query: 167 AKMKLIVNMIMGSMMNAFSEGLVLADKSGLS 197
             +K++ N I    M   +E   L  K GL+
Sbjct: 192 HYVKMVHNGIEYGDMQLIAEAYSLL-KGGLN 221


>2IZ1-A nrPDB
          Length = 474

 Score = 45.1 bits (105), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 47/202 (23%), Positives = 87/202 (43%), Gaps = 19/202 (9%)

Query: 4   GFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELV-EHG------ASVCESPAEVIKK 56
           G +G+ +MGK +++N+   G+ V ++NRT SK +E+  EH           E     ++K
Sbjct: 9   GVVGMAVMGKNLALNVESRGYTVAIYNRTTSKTEEVFKEHQDKNLVFTKTLEEFVGSLEK 68

Query: 57  CKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFV 116
            +  + M+    A  + +     +L  +  G   ID        +++ N  +   G  F+
Sbjct: 69  PRRIMLMVQAGAATDATI---KSLLPLLDIGDILIDGGNTHFPDTMRRNAELADSGINFI 125

Query: 117 EGPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRS--------FYLGQVGNGAK 168
              VSG +K A  G   ++  G K  ++   P F+ +  ++         Y+G  G G  
Sbjct: 126 GTGVSGGEKGALLGP-SMMPGGQKEAYDLVAPIFEQIAAKAPQDGKPCVAYMGANGAGHY 184

Query: 169 MKLIVNMIMGSMMNAFSEGLVL 190
           +K++ N I    M   +E   L
Sbjct: 185 VKMVHNGIEYGDMQLIAESYDL 206


>6FQY-A nrPDB
          Length = 468

 Score = 43.5 bits (101), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 60/258 (23%), Positives = 108/258 (41%), Gaps = 54/258 (20%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDE---------LVEHGASVCESPAE 52
           ++G +GL +MG+ +S+N+   GFK+ V+NRT  + +E         LV +G    E    
Sbjct: 3   DIGLIGLAVMGQNLSLNISSKGFKIGVYNRTYERTEETMKRAKEENLVVYGYKTVEELIN 62

Query: 53  VIKKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYID---MSTVDAETSLKINE--- 106
            +KK +  I ++    A  +V  +   +L+   +G   ID      +++E  +K+ +   
Sbjct: 63  NLKKPRKVILLIK---AGPAVDENISNILKHFEKGDIIIDGGNEWYINSERRIKLCKEKD 119

Query: 107 ------AITG--KGGRFVEGPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSF 158
                  ++G   G R+    + G  K A D    IL      +       +   G    
Sbjct: 120 VEYLAMGVSGGEAGARYGCSFMPGGSKYAYDCVKEILEKCSAQVGNSPCVTYIGPGSSGN 179

Query: 159 YLGQVGNGAK---MKLIV-------------NMIMGSMMNAFSEGL-----------VLA 191
           Y+  V NG +   M+LI              N  +  + N ++EG+           +LA
Sbjct: 180 YVKMVHNGIEYGDMQLISESYVIMKHILKYDNQKLSEVFNKWNEGILNSYLIEITANILA 239

Query: 192 DKSGLSSDTLLD-ILDLG 208
            K  L+++ L+D ILD+ 
Sbjct: 240 KKDDLTNNYLVDMILDIA 257


>4E21-A nrPDB
          Length = 358

 Score = 42.4 bits (98), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 56/241 (23%), Positives = 93/241 (38%), Gaps = 34/241 (14%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKK-CKY 59
           M++G +GLG MG  M   L K G +  V++  ++    L   G +   S  E   K  K 
Sbjct: 23  MQIGMIGLGRMGADMVRRLRKGGHECVVYDLNVNAVQALEREGIAGARSIEEFCAKLVKP 82

Query: 60  TIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGP 119
            +  L  P A +  +  +   L  +      ID      +  ++  + +  +G  +V+  
Sbjct: 83  RVVWLMVPAAVVDSMLQRMTPL--LAANDIVIDGGNSHYQDDIRRADQMRAQGITYVDVG 140

Query: 120 VSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLG-------------KRS-------FY 159
            SG     E G  +++  G+K   E   P F  L              KR         +
Sbjct: 141 TSGGIFGLERGYCLMI-GGEKQAVERLDPVFRTLAPGIGAAPRTPGREKREGTAELGYLH 199

Query: 160 LGQVGNGAKMKLIVNMIMGSMMNAFSEGLVL-----ADKSGLSSDTLLDILDLGAMTNPM 214
            G  G G  +K++ N I   +M A++EGL +     A K G  +D      +   + NP 
Sbjct: 200 CGPSGAGHFVKMVHNGIEYGLMAAYAEGLNILHHANAGKEGQGADA-----ETAPLRNPD 254

Query: 215 F 215
           F
Sbjct: 255 F 255


>1PGJ-A nrPDB
          Length = 478

 Score = 39.7 bits (91), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 47/216 (21%), Positives = 92/216 (42%), Gaps = 34/216 (15%)

Query: 15  MSMNLLKNGFKVTVWNRTLSKCDELVEHGAS-----------VCESPAEVIKKCKYTIAM 63
           +++N+ + GFKV V+NRT SK +E ++  AS             E+ A  +KK +  + +
Sbjct: 16  LALNIAEKGFKVAVFNRTYSKSEEFMKANASAPFAGNLKAFETMEAFAASLKKPRKALIL 75

Query: 64  LSDPCAA------LSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVE 117
           +    A       L  VF+KG +L         +D      +   +  + +   G RF+ 
Sbjct: 76  VQAGAATDSTIEQLKKVFEKGDIL---------VDTGNAHFKDQGRRAQQLEAAGLRFLG 126

Query: 118 GPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRS-------FYLGQVGNGAKMK 170
             +SG ++ A  G       G  +++EE  P  +    ++          G  G G+ +K
Sbjct: 127 MGISGGEEGARKGP-AFFPGGTLSVWEEIRPIVEAAAAKADDGRPCVTMNGSGGAGSCVK 185

Query: 171 LIVNMIMGSMMNAFSEGLVLADKSGLSSDTLLDILD 206
           +  N    +++  + E   +    GL++D +  +L+
Sbjct: 186 MYHNSGEYAILQIWGEVFDILRAMGLNNDEVAAVLE 221


>2P4Q-A nrPDB
          Length = 497

 Score = 38.5 bits (88), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 16/43 (37%), Positives = 26/43 (60%)

Query: 2  EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGA 44
          + G +GL +MG+ + +N   +GF V  +NRT SK D  + + A
Sbjct: 12 DFGLIGLAVMGQNLILNAADHGFTVCAYNRTQSKVDHFLANEA 54


>4GWK-A nrPDB
          Length = 484

 Score = 37.7 bits (86), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 15/43 (34%), Positives = 29/43 (67%)

Query: 2  EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGA 44
          ++  +GL +MG+ + +N+  +GF V  +NRT+SK D+ + + A
Sbjct: 6  DIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEA 48


>1PGO-A nrPDB
          Length = 482

 Score = 37.7 bits (86), Expect = 0.006,   Method: Compositional matrix adjust.
 Identities = 15/43 (34%), Positives = 29/43 (67%)

Query: 2  EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGA 44
          ++  +GL +MG+ + +N+  +GF V  +NRT+SK D+ + + A
Sbjct: 4  DIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEA 46


>2HK7-A nrPDB
          Length = 269

 Score = 36.2 bits (82), Expect = 0.015,   Method: Compositional matrix adjust.
 Identities = 23/61 (37%), Positives = 31/61 (50%), Gaps = 1/61 (1%)

Query: 6   LGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEH-GASVCESPAEVIKKCKYTIAML 64
           LG G   +A+   L+K G KV +WNRT  K  +L +     V  SP EVI K +  +   
Sbjct: 129 LGAGGASRAVIYALVKEGAKVFLWNRTKEKAIKLAQKFPLEVVNSPEEVIDKVQVIVNTT 188

Query: 65  S 65
           S
Sbjct: 189 S 189


>4YPO-A nrPDB
          Length = 333

 Score = 34.7 bits (78), Expect = 0.056,   Method: Compositional matrix adjust.
 Identities = 21/69 (30%), Positives = 33/69 (47%)

Query: 2  EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61
          +VG +G G  G A S++L  +G +V V  +  S+    VE      ++PAEV K     +
Sbjct: 16 KVGVIGYGSQGHAHSLSLRDSGVQVRVGLKQGSRSRPKVEEQGLDVDTPAEVAKWADVVM 75

Query: 62 AMLSDPCAA 70
           +  D   A
Sbjct: 76 VLAPDTAQA 84


>4DGS-A nrPDB
          Length = 340

 Score = 33.5 bits (75), Expect = 0.10,   Method: Compositional matrix adjust.
 Identities = 18/57 (31%), Positives = 27/57 (47%), Gaps = 1/57 (1%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNR-TLSKCDELVEHGASVCESPAEVIKKC 57
            +G LGLG +G+A++      G  V  WNR TLS  D +           ++V+  C
Sbjct: 173 RIGVLGLGQIGRALASRAEAFGMSVRYWNRSTLSGVDWIAHQSPVDLARDSDVLAVC 229


>6C6P-A nrPDB
          Length = 458

 Score = 32.3 bits (72), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 16/39 (41%), Positives = 25/39 (64%)

Query: 2  EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELV 40
          EV  +G G++G A++  L ++G KVTV  R L + D +V
Sbjct: 9  EVIIVGAGVLGSALAAVLSRDGRKVTVIERDLKEPDRIV 47


>2D0I-A nrPDB
          Length = 333

 Score = 32.0 bits (71), Expect = 0.30,   Method: Compositional matrix adjust.
 Identities = 13/29 (44%), Positives = 20/29 (68%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNR 31
           VG LG+G +GKA++  L+  G K+  W+R
Sbjct: 149 VGILGMGAIGKAIARRLIPFGVKLYYWSR 177


>4WEQ-A nrPDB
          Length = 341

 Score = 31.2 bits (69), Expect = 0.51,   Method: Compositional matrix adjust.
 Identities = 12/30 (40%), Positives = 20/30 (66%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRT 32
           VG +G+G++G+  +  L   GFKV  W+R+
Sbjct: 164 VGIMGMGVLGQDAARKLAAMGFKVIGWSRS 193


>2F1K-A nrPDB
          Length = 279

 Score = 31.2 bits (69), Expect = 0.51,   Method: Compositional matrix adjust.
 Identities = 13/41 (31%), Positives = 27/41 (65%)

Query: 1  MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVE 41
          M++G +GLG++G +++ +L + G  +   +R  S C++ VE
Sbjct: 1  MKIGVVGLGLIGASLAGDLRRRGHYLIGVSRQQSTCEKAVE 41


>6C55-A nrPDB
          Length = 340

 Score = 31.2 bits (69), Expect = 0.58,   Method: Compositional matrix adjust.
 Identities = 19/65 (29%), Positives = 30/65 (46%), Gaps = 1/65 (1%)

Query: 2  EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61
          ++  +G G  G A + NL  NG+ V +  R     D+  E G  V    AE +K+    +
Sbjct: 19 KIAVVGYGSQGHAHAQNLKDNGYDVVIGIRPGRSFDKAKEDGFDVFPV-AEAVKQADVIM 77

Query: 62 AMLSD 66
           +L D
Sbjct: 78 VLLPD 82


>3PGJ-A nrPDB
          Length = 302

 Score = 30.8 bits (68), Expect = 0.76,   Method: Compositional matrix adjust.
 Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 9/74 (12%)

Query: 26  VTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI-AMLSDPCAALS--------VVFD 76
           +TV NRT +K ++L E  A+  E  A+  ++ K +   +++   A+L         V+F 
Sbjct: 174 ITVTNRTFAKAEQLAELVAAYGEVKAQAFEQLKQSYDVIINSTSASLDGELPAIDPVIFS 233

Query: 77  KGGVLEQICEGKGY 90
              V   +  GKGY
Sbjct: 234 SRSVCYDMMYGKGY 247


>1TXG-A nrPDB
          Length = 335

 Score = 30.4 bits (67), Expect = 0.81,   Method: Compositional matrix adjust.
 Identities = 14/29 (48%), Positives = 19/29 (65%)

Query: 1  MEVGFLGLGIMGKAMSMNLLKNGFKVTVW 29
          M V  LG G MG A+S+ L+ NG +V +W
Sbjct: 1  MIVSILGAGAMGSALSVPLVDNGNEVRIW 29


>5TSD-A nrPDB
          Length = 322

 Score = 29.6 bits (65), Expect = 1.7,   Method: Compositional matrix adjust.
 Identities = 14/30 (46%), Positives = 18/30 (60%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRT 32
           VG +GLGI+G+     L   GF V  W+RT
Sbjct: 145 VGVMGLGILGQDAVAKLKVMGFNVIGWSRT 174


>3K96-A nrPDB
          Length = 356

 Score = 28.9 bits (63), Expect = 2.5,   Method: Compositional matrix adjust.
 Identities = 13/43 (30%), Positives = 22/43 (51%)

Query: 3  VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGAS 45
          +  LG G  G A+++ L + G KV +W+      DE+   G +
Sbjct: 32 IAILGAGSWGTALALVLARKGQKVRLWSYESDHVDEMQAEGVN 74


>4N18-A nrPDB
          Length = 332

 Score = 28.9 bits (63), Expect = 3.0,   Method: Compositional matrix adjust.
 Identities = 10/32 (31%), Positives = 21/32 (65%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRT 32
             +G +GLG +G  ++  L + G++V+ W+R+
Sbjct: 157 FHIGIMGLGEIGGYIADQLARLGYRVSGWSRS 188


>1BG6-A nrPDB
          Length = 359

 Score = 28.5 bits (62), Expect = 3.6,   Method: Compositional matrix adjust.
 Identities = 15/45 (33%), Positives = 21/45 (46%)

Query: 6  LGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESP 50
          LGLG  G A +  L   G  V  W+    +  E+ + GA + E P
Sbjct: 10 LGLGNGGHAFAAYLALKGQSVLAWDIDAQRIKEIQDRGAIIAEGP 54


>1T0K-B nrPDB
          Length = 105

 Score = 28.5 bits (62), Expect = 3.7,   Method: Compositional matrix adjust.
 Identities = 21/74 (28%), Positives = 35/74 (47%), Gaps = 1/74 (1%)

Query: 93  MSTVDAETSLKINEAITGKGGRFVEGPVSGSKKPAE-DGQLIILAAGDKALFEESIPAFD 151
           M+ V ++ S+    A+  K G++  G  S  K   +   +LII+AA    L +  +  + 
Sbjct: 1   MAPVKSQESINQKLALVIKSGKYTLGYKSTVKSLRQGKSKLIIIAANTPVLRKSELEYYA 60

Query: 152 VLGKRSFYLGQVGN 165
           +L K   Y  Q GN
Sbjct: 61  MLSKTKVYYFQGGN 74


>5JOY-A nrPDB
          Length = 516

 Score = 28.1 bits (61), Expect = 4.1,   Method: Compositional matrix adjust.
 Identities = 15/51 (29%), Positives = 26/51 (50%), Gaps = 4/51 (7%)

Query: 72  SVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEA---ITGKGGRFVEGP 119
           S+ F+ G     +    GYI++  +D  T  +++ +     G GGR+ EGP
Sbjct: 132 SLYFEDGKCF-MVSNPDGYINLCEIDPMTGKQLSSSKRIWNGTGGRYAEGP 181


>6IUM-B nrPDB
          Length = 701

 Score = 27.7 bits (60), Expect = 5.6,   Method: Compositional matrix adjust.
 Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAE-VIKKCKYT 60
           +V  +G G MG  +SMN L  G  VT+    L    E ++ G  +     E   KK K T
Sbjct: 294 KVAVIGAGTMGGGISMNFLNAGIPVTI----LETKQEALDRGVGIIRKNYENSAKKGKLT 349


>3GGO-A nrPDB
          Length = 314

 Score = 27.7 bits (60), Expect = 6.2,   Method: Compositional matrix adjust.
 Identities = 36/146 (24%), Positives = 64/146 (43%), Gaps = 17/146 (11%)

Query: 6   LGLGIMGKAMSMNLLKNGFKVTVWN-----RTLSKCDELVEHGASVCESPAEVIKKCKYT 60
           +G+G MG + + +L ++GFK  ++       ++SK  +L      + E    + K   ++
Sbjct: 39  VGVGFMGGSFAKSLRRSGFKGKIYGYDINPESISKAVDL----GIIDEGTTSIAKVEDFS 94

Query: 61  --IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEG 118
               MLS P      +  K   +  + E     D  +V  +    + E I GK  RFV G
Sbjct: 95  PDFVMLSSPVRTFREIAKKLSYI--LSEDATVTDQGSVKGKLVYDL-ENILGK--RFVGG 149

Query: 119 -PVSGSKKPAEDGQLIILAAGDKALF 143
            P++G++K   +  L  L  G K + 
Sbjct: 150 HPIAGTEKSGVEYSLDNLYEGKKVIL 175


>2G5C-A nrPDB
          Length = 281

 Score = 27.7 bits (60), Expect = 6.6,   Method: Compositional matrix adjust.
 Identities = 36/146 (24%), Positives = 64/146 (43%), Gaps = 17/146 (11%)

Query: 6   LGLGIMGKAMSMNLLKNGFKVTVWN-----RTLSKCDELVEHGASVCESPAEVIKKCKYT 60
           +G+G MG + + +L ++GFK  ++       ++SK  +L      + E    + K   ++
Sbjct: 7   VGVGFMGGSFAKSLRRSGFKGKIYGYDINPESISKAVDL----GIIDEGTTSIAKVEDFS 62

Query: 61  --IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEG 118
               MLS P      +  K   +  + E     D  +V  +    + E I GK  RFV G
Sbjct: 63  PDFVMLSSPVRTFREIAKKLSYI--LSEDATVTDQGSVKGKLVYDL-ENILGK--RFVGG 117

Query: 119 -PVSGSKKPAEDGQLIILAAGDKALF 143
            P++G++K   +  L  L  G K + 
Sbjct: 118 HPIAGTEKSGVEYSLDNLYEGKKVIL 143


>4XA8-A nrPDB
          Length = 320

 Score = 26.9 bits (58), Expect = 9.2,   Method: Compositional matrix adjust.
 Identities = 15/32 (46%), Positives = 22/32 (68%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRT 32
           + VG LGLG +G A ++ L ++GF V  W+RT
Sbjct: 145 IRVGVLGLGDLGAAAALELARHGFDVRGWSRT 176


Searching..................................................done


Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

3DOJ-A nrPDB                                                          342   8e-95
2UYY-A nrPDB                                                          301   3e-82
3PEF-A nrPDB                                                          298   1e-81
3PDU-A nrPDB                                                          288   1e-78
5XVH-A nrPDB                                                          283   5e-77
1YB4-A nrPDB                                                          282   1e-76
1VPD-A nrPDB                                                          278   2e-75
5JE8-A nrPDB                                                          272   1e-73
2GF2-A nrPDB                                                          271   2e-73
3CKY-A nrPDB                                                          269   1e-72
4D3F-A nrPDB                                                          252   1e-67
4DLL-A nrPDB                                                          250   7e-67
4GBJ-A nrPDB                                                          241   2e-64
4OQY-A nrPDB                                                          241   2e-64
2CVZ-A nrPDB                                                          241   3e-64
5Y8M-A nrPDB                                                          224   3e-59
3G0O-A nrPDB                                                          221   3e-58
4OQZ-A nrPDB                                                          219   1e-57
3Q3C-A nrPDB                                                          218   2e-57
5U5G-A nrPDB                                                          212   1e-55
5A9T-A nrPDB                                                          211   4e-55
4D3S-A nrPDB                                                          210   6e-55
3ZHB-A nrPDB                                                          208   2e-54
2W8Z-A nrPDB                                                          203   7e-53
5G6R-A nrPDB                                                          201   2e-52
5OCM-A nrPDB                                                          191   4e-49
3QHA-A nrPDB                                                          191   4e-49
2IZ1-A nrPDB                                                          189   2e-48
2ZYA-A nrPDB                                                          186   1e-47
3L6D-A nrPDB                                                          186   1e-47
6FQY-A nrPDB                                                          169   1e-42
6EOI-A nrPDB                                                          169   2e-42
4E21-A nrPDB                                                          168   2e-42
1PGJ-A nrPDB                                                          159   9e-40

Sequences not found previously or not previously below threshold:

1PGO-A nrPDB                                                          146   8e-36
4GWK-A nrPDB                                                          140   4e-34
2P4Q-A nrPDB                                                          140   4e-34
4R16-A nrPDB                                                           67   1e-11
2Y0D-A nrPDB                                                           59   3e-09
2F1K-A nrPDB                                                           56   2e-08
2D0I-A nrPDB                                                           49   2e-06
4DGS-A nrPDB                                                           49   2e-06
3OJO-A nrPDB                                                           47   8e-06
4OM8-A nrPDB                                                           47   9e-06
2WWR-A nrPDB                                                           46   2e-05
5AOV-A nrPDB                                                           46   2e-05
4YPO-A nrPDB                                                           46   2e-05
1GPJ-A nrPDB                                                           45   3e-05
3KBO-A nrPDB                                                           45   3e-05
6HD1-C nrPDB                                                           44   5e-05
4G2N-A nrPDB                                                           44   7e-05
4N18-A nrPDB                                                           44   8e-05
3TRI-A nrPDB                                                           44   9e-05
5WHX-A nrPDB                                                           44   9e-05
3GGO-A nrPDB                                                           44   1e-04
2G5C-A nrPDB                                                           44   1e-04
4KQW-A nrPDB                                                           44   1e-04
6BII-A nrPDB                                                           43   2e-04
1MV8-A nrPDB                                                           42   2e-04
5UOG-A nrPDB                                                           42   2e-04
3VTF-A nrPDB                                                           42   2e-04
4EBF-A nrPDB                                                           42   2e-04
2I99-A nrPDB                                                           42   2e-04
4TSK-A nrPDB                                                           42   3e-04
2HK7-A nrPDB                                                           42   3e-04
1NP3-A nrPDB                                                           42   4e-04
3MOG-A nrPDB                                                           42   4e-04
6C55-A nrPDB                                                           41   6e-04
2DLD-A nrPDB                                                           41   7e-04
4XA8-A nrPDB                                                           41   8e-04
1TXG-A nrPDB                                                           40   8e-04
4WEQ-A nrPDB                                                           40   8e-04
3JTM-A nrPDB                                                           40   9e-04
5B37-A nrPDB                                                           40   0.001
1BG6-A nrPDB                                                           40   0.001
3DC2-A nrPDB                                                           40   0.001
6G1M-A nrPDB                                                           40   0.001
5Z1Z-A nrPDB                                                           40   0.002
1YON-A nrPDB                                                           39   0.002
5T57-A nrPDB                                                           39   0.003
3G79-A nrPDB                                                           39   0.003
5TSD-A nrPDB                                                           39   0.003
1GDH-A nrPDB                                                           38   0.004
1ZEJ-A nrPDB                                                           38   0.005
4A7P-A nrPDB                                                           38   0.005
5C5I-A nrPDB                                                           38   0.005
2AHR-A nrPDB                                                           38   0.005
1J49-A nrPDB                                                           38   0.006
4ZGS-A nrPDB                                                           38   0.006
4BVA-A nrPDB                                                           38   0.006
6HRD-A nrPDB                                                           37   0.007
5N2I-A nrPDB                                                           37   0.008
4B3J-A nrPDB                                                           37   0.008
1HL3-A nrPDB                                                           37   0.009
5E4R-A nrPDB                                                           37   0.010
2QYS-A nrPDB                                                           37   0.010
1YQG-A nrPDB                                                           37   0.011
2CUK-A nrPDB                                                           37   0.013
1ZCJ-A nrPDB                                                           37   0.013
3HDH-A nrPDB                                                           37   0.013
6ABJ-A nrPDB                                                           37   0.013
4XDZ-A nrPDB                                                           37   0.014
4N7R-A nrPDB                                                           36   0.015
1F14-A nrPDB                                                           36   0.015
3ZWA-A nrPDB                                                           36   0.016
2VHY-A nrPDB                                                           36   0.020
4J90-A nrPDB                                                           36   0.021
2RCY-A nrPDB                                                           35   0.028
6IUM-B nrPDB                                                           35   0.029
3K96-A nrPDB                                                           35   0.032
3BA1-A nrPDB                                                           35   0.033
1CER-O nrPDB                                                           35   0.033
4MIE-A nrPDB                                                           35   0.034
2EV9-A nrPDB                                                           35   0.037
4DYD-A nrPDB                                                           35   0.039
1QP8-A nrPDB                                                           35   0.041
4ZCC-A nrPDB                                                           35   0.042
2YQ5-A nrPDB                                                           35   0.052
2HMT-A nrPDB                                                           34   0.055
5BUT-A nrPDB                                                           34   0.059
5VJ7-A nrPDB                                                           34   0.064
5YEQ-A nrPDB                                                           34   0.068
6IH4-A nrPDB                                                           34   0.069
3KB6-A nrPDB                                                           34   0.092
3I83-A nrPDB                                                           34   0.093
6ACQ-A nrPDB                                                           34   0.097
2RIR-A nrPDB                                                           34   0.099
3KKJ-A nrPDB                                                           34   0.11 
5JFC-L nrPDB                                                           34   0.12 
4LSW-A nrPDB                                                           33   0.13 
4A5O-A nrPDB                                                           33   0.14 
3TWO-A nrPDB                                                           33   0.15 
3FR8-A nrPDB                                                           33   0.18 
4A6N-B nrPDB                                                           33   0.21 
1JAY-A nrPDB                                                           33   0.21 
2OME-A nrPDB                                                           32   0.22 
6NRP-A nrPDB                                                           32   0.31 
3LK7-A nrPDB                                                           32   0.36 
5OES-A nrPDB                                                           32   0.37 
2EGG-A nrPDB                                                           32   0.38 
4KUG-A nrPDB                                                           32   0.39 
4CUK-A nrPDB                                                           32   0.42 
1GEG-A nrPDB                                                           32   0.44 
1A5Z-A nrPDB                                                           32   0.45 
5Y77-A nrPDB                                                           31   0.50 
4PRK-A nrPDB                                                           31   0.50 
3WNV-A nrPDB                                                           31   0.51 
2EW2-A nrPDB                                                           31   0.52 
1NYT-A nrPDB                                                           31   0.52 
6C6P-A nrPDB                                                           31   0.55 
4FQ8-A nrPDB                                                           31   0.57 
3QY9-A nrPDB                                                           31   0.62 
4K28-A nrPDB                                                           31   0.66 
4HY3-A nrPDB                                                           31   0.67 
3GT0-A nrPDB                                                           31   0.67 
4FSH-A nrPDB                                                           31   0.68 
4OH1-A nrPDB                                                           31   0.69 
1VC2-A nrPDB                                                           30   0.81 
1XDW-A nrPDB                                                           30   0.87 
1PS9-A nrPDB                                                           30   0.96 
3PGJ-A nrPDB                                                           30   1.0  
3DDL-A nrPDB                                                           30   1.1  
5NMX-A nrPDB                                                           30   1.2  
5X6R-A nrPDB                                                           30   1.2  
1DOH-A nrPDB                                                           30   1.2  
2WTB-A nrPDB                                                           30   1.2  
3W8X-A nrPDB                                                           30   1.4  
2E18-A nrPDB                                                           30   1.4  
1BW9-B nrPDB                                                           30   1.5  
6APH-A nrPDB                                                           30   1.5  
3NT2-A nrPDB                                                           30   1.6  
3WFI-A nrPDB                                                           30   1.7  
1ZFN-A nrPDB                                                           30   1.7  
2EKL-A nrPDB                                                           30   1.7  
6ABI-A nrPDB                                                           30   1.8  
3UP5-A nrPDB                                                           29   1.8  
3KTD-A nrPDB                                                           29   1.9  
4PZE-A nrPDB                                                           29   1.9  
2TMD-A nrPDB                                                           29   1.9  
5BSH-A nrPDB                                                           29   2.0  
2BW0-A nrPDB                                                           29   2.0  
3J9R-A nrPDB                                                           29   2.0  
3K6J-A nrPDB                                                           29   2.0  
1HYH-A nrPDB                                                           29   2.0  
2CBN-A nrPDB                                                           29   2.1  
4OVI-A nrPDB                                                           29   2.2  
3L9X-A nrPDB                                                           29   2.2  
4YRY-B nrPDB                                                           29   2.6  
1E5Q-A nrPDB                                                           29   2.7  
5U9P-A nrPDB                                                           29   3.2  
3OSU-A nrPDB                                                           29   3.4  
2DBZ-A nrPDB                                                           29   3.5  
4J0E-A nrPDB                                                           29   3.6  
2PAJ-A nrPDB                                                           29   3.6  
2PB9-A nrPDB                                                           29   3.8  
6BMQ-A nrPDB                                                           28   3.9  
3ZV3-A nrPDB                                                           28   4.0  
5EVJ-A nrPDB                                                           28   4.2  
6IHE-A nrPDB                                                           28   4.4  
6J0Z-C nrPDB                                                           28   4.8  
1UB3-A nrPDB                                                           28   5.0  
2DZB-A nrPDB                                                           28   5.3  
3WYE-A nrPDB                                                           28   5.5  
1PJB-A nrPDB                                                           28   5.6  
5IOB-A nrPDB                                                           28   5.9  
3HWR-A nrPDB                                                           28   5.9  
2DC1-A nrPDB                                                           28   6.3  
4OMU-A nrPDB                                                           28   6.7  
5XGV-A nrPDB                                                           27   6.9  
1LSS-A nrPDB                                                           27   7.0  
5UAU-A nrPDB                                                           27   7.4  
2V3B-A nrPDB                                                           27   7.4  
5CJE-A nrPDB                                                           27   8.3  
2VDC-G nrPDB                                                           27   8.6  
2GRA-A nrPDB                                                           27   8.6  
4HB9-A nrPDB                                                           27   9.0  
4Y4N-A nrPDB                                                           27   9.3  

>3DOJ-A nrPDB
          Length = 310

 Score =  342 bits (878), Expect = 8e-95,   Method: Composition-based stats.
 Identities = 289/289 (100%), Positives = 289/289 (100%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60
           MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT
Sbjct: 22  MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 81

Query: 61  IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120
           IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV
Sbjct: 82  IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 141

Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 180
           SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM
Sbjct: 142 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 201

Query: 181 MNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDM 240
           MNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDM
Sbjct: 202 MNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDM 261

Query: 241 RLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVKFSRE 289
           RLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVKFSRE
Sbjct: 262 RLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVKFSRE 310


>2UYY-A nrPDB
          Length = 316

 Score =  301 bits (770), Expect = 3e-82,   Method: Composition-based stats.
 Identities = 140/283 (49%), Positives = 189/283 (66%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61
           ++GFLGLG+MG  +  NLLK G  VTVWNRT  KCD  ++ GA +  +PAEV+  C  T 
Sbjct: 32  KIGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKCDLFIQEGARLGRTPAEVVSTCDITF 91

Query: 62  AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121
           A +SDP AA  +V    GVL+ I  GK Y+DMSTVDA+T  ++ + I  +GGRF+E PVS
Sbjct: 92  ACVSDPKAAKDLVLGPSGVLQGIRPGKCYVDMSTVDADTVTELAQVIVSRGGRFLEAPVS 151

Query: 122 GSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMM 181
           G+++ + DG L+ILAAGD+ L+E+    F  +GK SF+LG+VGN AKM LIVNM+ GS M
Sbjct: 152 GNQQLSNDGMLVILAAGDRGLYEDCSSCFQAMGKTSFFLGEVGNAAKMMLIVNMVQGSFM 211

Query: 182 NAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDMR 241
              +EGL LA  +G S  TLLDIL+ G + +     K  ++ + ++ P F LK+ QKD+R
Sbjct: 212 ATIAEGLTLAQVTGQSQQTLLDILNQGQLASIFLDQKCQNILQGNFKPDFYLKYIQKDLR 271

Query: 242 LALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAV 284
           LA+ALGD      P+AAAANE +K+A++L   D D SAV  A 
Sbjct: 272 LAIALGDAVNHPTPMAAAANEVYKRAKALDQSDNDMSAVYRAY 314


>3PEF-A nrPDB
          Length = 287

 Score =  298 bits (764), Expect = 1e-81,   Method: Composition-based stats.
 Identities = 159/285 (55%), Positives = 205/285 (71%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60
            + GF+GLGIMG AM+ NL+K G  VT+WNR+  K +EL   GA    +P EV++ C  T
Sbjct: 2   QKFGFIGLGIMGSAMAKNLVKAGCSVTIWNRSPEKAEELAALGAERAATPCEVVESCPVT 61

Query: 61  IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120
            AML+DP AA  V F K GVLE I EG+GY+DMSTVD  TS +I  A+  KGGRF+E PV
Sbjct: 62  FAMLADPAAAEEVCFGKHGVLEGIGEGRGYVDMSTVDPATSQRIGVAVVAKGGRFLEAPV 121

Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 180
           SGSKKPAEDG LIILAAGD+ L++E++P F+ +GK+  +LG VG GA+MKL+VNM+MG M
Sbjct: 122 SGSKKPAEDGTLIILAAGDRNLYDEAMPGFEKMGKKIIHLGDVGKGAEMKLVVNMVMGGM 181

Query: 181 MNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDM 240
           M  F EGL L +K+GL++D +LD++  GAM NPMF  KG  +   ++ PAFPLKH QKD+
Sbjct: 182 MACFCEGLALGEKAGLATDAILDVIGAGAMANPMFALKGGLIRDRNFAPAFPLKHMQKDL 241

Query: 241 RLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVK 285
           RLA+ALGD     +  +AAANE FK AR+ G GD DFSA+ +  +
Sbjct: 242 RLAVALGDRVGQPLVASAAANELFKGARAAGFGDEDFSAIFKTYE 286


>3PDU-A nrPDB
          Length = 287

 Score =  288 bits (738), Expect = 1e-78,   Method: Composition-based stats.
 Identities = 164/282 (58%), Positives = 198/282 (70%)

Query: 4   GFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIAM 63
           GFLGLGIMG  M+ NL++ GF VTVWNR  +KC  LV  GA    SPAEV   C  TIAM
Sbjct: 5   GFLGLGIMGGPMAANLVRAGFDVTVWNRNPAKCAPLVALGARQASSPAEVCAACDITIAM 64

Query: 64  LSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSGS 123
           L+DP AA  V F   GVLE I  G+GYIDMSTVD ETS  I  A+T +GGRF+E PVSG+
Sbjct: 65  LADPAAAREVCFGANGVLEGIGGGRGYIDMSTVDDETSTAIGAAVTARGGRFLEAPVSGT 124

Query: 124 KKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMMNA 183
           KKPAEDG LIILAAGD++LF ++ PAF  LGK+  +LG+VG GA+MKL+VNMIMG MM A
Sbjct: 125 KKPAEDGTLIILAAGDQSLFTDAGPAFAALGKKCLHLGEVGQGARMKLVVNMIMGQMMTA 184

Query: 184 FSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDMRLA 243
             EG+ L    GL    LL++LD GAM NPMFKGKG  +    +P +FPLKH QKD+RLA
Sbjct: 185 LGEGMALGRNCGLDGGQLLEVLDAGAMANPMFKGKGQMLLSGEFPTSFPLKHMQKDLRLA 244

Query: 244 LALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVK 285
           + LGD     +  AA ANE+FK+AR+ G  D DF+AV   ++
Sbjct: 245 VELGDRLGQPLHGAATANESFKRARAAGHADEDFAAVFRVLE 286


>5XVH-A nrPDB
          Length = 306

 Score =  283 bits (725), Expect = 5e-77,   Method: Composition-based stats.
 Identities = 99/280 (35%), Positives = 142/280 (50%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60
           M VGF+GLGIMG  M+ +LLK GF   V+NRT  K     E G  V ESPA++ K+    
Sbjct: 21  MRVGFIGLGIMGGPMATHLLKAGFLAAVYNRTREKTKPFAEAGVYVAESPADLAKRVDVV 80

Query: 61  IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120
           I M+SD      V+F   GV+E    G   +DMST   + + K  E +   G  F++ PV
Sbjct: 81  IVMVSDAPDVEQVLFGPSGVVEGARPGLIVVDMSTNSPDWARKFAERLAQYGIEFLDAPV 140

Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 180
           +G +K A +G L I+  G + LF   +P F  +G+   Y+G VG G  MKL+  +++   
Sbjct: 141 TGGQKGAIEGTLTIMVGGKEELFHRLLPIFKAMGRDIVYMGPVGYGQAMKLVNQVVVALN 200

Query: 181 MNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDM 240
             A  EGL LA   GL  D + ++L  GA  +   +   P + K    P F  +H +KD+
Sbjct: 201 TVAMVEGLKLAKALGLDMDKVAEVLTRGAARSGAIELYLPKLLKGDLSPGFKAEHLKKDL 260

Query: 241 RLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAV 280
              L    +  V +P A  A E ++K    G G L   A+
Sbjct: 261 GYVLEEARKRGVKLPGAELAYELYRKMVEDGAGSLGIHAL 300


>1YB4-A nrPDB
          Length = 295

 Score =  282 bits (721), Expect = 1e-76,   Method: Composition-based stats.
 Identities = 84/286 (29%), Positives = 144/286 (50%), Gaps = 1/286 (0%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60
           M++GF+GLGIMG  M++NL + G ++ V        DEL+  GA   E+  +V +     
Sbjct: 4   MKLGFIGLGIMGSPMAINLARAGHQLHVTTIGPV-ADELLSLGAVNVETARQVTEFADII 62

Query: 61  IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120
             M+ D      V+F + G  +   +GK  +DMS++    + +  + +   G  +++ PV
Sbjct: 63  FIMVPDTPQVEDVLFGEHGCAKTSLQGKTIVDMSSISPIETKRFAQRVNEMGADYLDAPV 122

Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 180
           SG +  A +G L I+  G++ +F+   P FD+LGK    +G  G+G   K+   +I+   
Sbjct: 123 SGGEIGAREGTLSIMVGGEQKVFDRVKPLFDILGKNITLVGGNGDGQTCKVANQIIVALN 182

Query: 181 MNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDM 240
           + A SE LV A K+G     +   L  G  ++ + +  G  M   ++ P F +   QKD+
Sbjct: 183 IEAVSEALVFASKAGADPVRVRQALMGGFASSRILEVHGERMINRTFEPGFKIALHQKDL 242

Query: 241 RLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVKF 286
            LAL      A+++P  A   E F    + G   LD SA+++A++ 
Sbjct: 243 NLALQSAKALALNLPNTATCQELFNTCAANGGSQLDHSAMVQALEL 288


>1VPD-A nrPDB
          Length = 299

 Score =  278 bits (711), Expect = 2e-75,   Method: Composition-based stats.
 Identities = 86/280 (30%), Positives = 140/280 (50%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60
           M+VGF+GLGIMGK MS NLLK G+ + V +R      +++  GA    +   + ++C   
Sbjct: 6   MKVGFIGLGIMGKPMSKNLLKAGYSLVVSDRNPEAIADVIAAGAETASTAKAIAEQCDVI 65

Query: 61  IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120
           I ML +      V   + G++E    G   IDMS++    S +I++A+  KG   ++ PV
Sbjct: 66  ITMLPNSPHVKEVALGENGIIEGAKPGTVLIDMSSIAPLASREISDALKAKGVEMLDAPV 125

Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 180
           SG +  A DG L ++  GDKA+F++       +     + G +G G   KL   +I+   
Sbjct: 126 SGGEPKAIDGTLSVMVGGDKAIFDKYYDLMKAMAGSVVHTGDIGAGNVTKLANQVIVALN 185

Query: 181 MNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDM 240
           + A SE L LA K+G++ D +   +  G   + +   K P +   ++ P F +    KD+
Sbjct: 186 IAAMSEALTLATKAGVNPDLVYQAIRGGLAGSTVLDAKAPMVMDRNFKPGFRIDLHIKDL 245

Query: 241 RLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAV 280
             AL         +P+ AA  E  +  R+ G G+ D SA+
Sbjct: 246 ANALDTSHGVGAQLPLTAAVMEMMQALRADGHGNDDHSAL 285


>5JE8-A nrPDB
          Length = 302

 Score =  272 bits (696), Expect = 1e-73,   Method: Composition-based stats.
 Identities = 79/285 (27%), Positives = 140/285 (49%), Gaps = 2/285 (0%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61
           ++GF+GLG MG  MS NL+K+G+ V   +          + G  +  S +++ + C    
Sbjct: 9   KIGFIGLGNMGLPMSKNLVKSGYTVYGVDLNKEAEASFEKEGGIIGLSISKLAETCDVVF 68

Query: 62  AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121
             L  P A  +V F   G+ E       +ID STV  + + ++ EA   K   F+  PVS
Sbjct: 69  TSLPSPRAVEAVYFGAEGLFENGHSNVVFIDTSTVSPQLNKQLEEAAKEKKVDFLAAPVS 128

Query: 122 GSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQ-VGNGAKMKLIVNMIMGSM 180
           G    AE+  L  +  G K ++E++     VLG   F++ + + +G  +KLI N+++G  
Sbjct: 129 GGVIGAENRTLTFMVGGSKDVYEKTESIMGVLGANIFHVSEQIDSGTTVKLINNLLIGFY 188

Query: 181 MNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFK-GKGPSMNKSSYPPAFPLKHQQKD 239
               SE L LA K+ +  D + DIL++    + +++      +   +Y P F +   +KD
Sbjct: 189 TAGVSEALTLAKKNNMDLDKMFDILNVSYGQSRIYERNYKSFIAPENYEPGFTVNLLKKD 248

Query: 240 MRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAV 284
           +  A+ L  E+ + +PV+      + +A   G G+ D +A+ + V
Sbjct: 249 LGFAVDLAKESELHLPVSEMLLNVYDEASQAGYGENDMAALYKKV 293


>2GF2-A nrPDB
          Length = 296

 Score =  271 bits (694), Expect = 2e-73,   Method: Composition-based stats.
 Identities = 77/292 (26%), Positives = 131/292 (44%), Gaps = 7/292 (2%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60
           M VGF+GLG MG  M+ NL+K+G+ + +++     C E  + G  V  SPA+V +K    
Sbjct: 1   MPVGFIGLGNMGNPMAKNLMKHGYPLIIYDVFPDACKEFQDAGEQVVSSPADVAEKADRI 60

Query: 61  IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120
           I ML     A+       G+L+++ +G   ID ST+D   S ++ + +   G  F++ PV
Sbjct: 61  ITMLPTSINAIEAYSGANGILKKVKKGSLLIDSSTIDPAVSKELAKEVEKMGAVFMDAPV 120

Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 180
           SG    A  G L  +  G +  F  +      +G    Y G VG G   K+  NM++   
Sbjct: 121 SGGVGAARSGNLTFMVGGVEDEFAAAQELLGCMGSNVVYCGAVGTGQAAKICNNMLLAIS 180

Query: 181 MNAFSEGLVLADKSGLSSDTLLDILDLGAMT--NPMFKGKGPSMNKS-----SYPPAFPL 233
           M   +E + L  + GL    L  IL++ +    +       P +        +Y   F  
Sbjct: 181 MIGTAEAMNLGIRLGLDPKLLAKILNMSSGRCWSSDTYNPVPGVMDGVPSANNYQGGFGT 240

Query: 234 KHQQKDMRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVK 285
               KD+ LA          + + + A++ ++   + G    DFS+V + ++
Sbjct: 241 TLMAKDLGLAQDSATSTKSPILLGSLAHQIYRMMCAKGYSKKDFSSVFQFLR 292


>3CKY-A nrPDB
          Length = 301

 Score =  269 bits (687), Expect = 1e-72,   Method: Composition-based stats.
 Identities = 94/286 (32%), Positives = 152/286 (53%), Gaps = 1/286 (0%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60
           +++GF+GLG MGK M++NLLK G  V  ++   +    +V  GA  CE+  +V       
Sbjct: 5   IKIGFIGLGAMGKPMAINLLKEGVTVYAFDLMEANVAAVVAQGAQACENNQKVAAASDII 64

Query: 61  IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120
              L +     +V+   GGVL     G   +DMS+V   ++LK+ +    KG  +V+ PV
Sbjct: 65  FTSLPNAGIVETVMNGPGGVLSACKAGTVIVDMSSVSPSSTLKMAKVAAEKGIDYVDAPV 124

Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 180
           SG  K AE G L I+    +A+FE+  P   V+GK  +++G  G G  +K++ N+++G  
Sbjct: 125 SGGTKGAEAGTLTIMVGASEAVFEKIQPVLSVIGKDIYHVGDTGAGDAVKIVNNLLLGCN 184

Query: 181 MNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPS-MNKSSYPPAFPLKHQQKD 239
           M + +E LVL  K GL  +T+ +I+   +  +   + K    +    +   F +  Q KD
Sbjct: 185 MASLAEALVLGVKCGLKPETMQEIIGKSSGRSYAMEAKMEKFIMSGDFAGGFAMDLQHKD 244

Query: 240 MRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVK 285
           + LAL  G E  V +P+ A A + F+  R++GLG  D SAVI+  +
Sbjct: 245 LGLALEAGKEGNVPLPMTAMATQIFEGGRAMGLGREDMSAVIKVWE 290


>4D3F-A nrPDB
          Length = 310

 Score =  252 bits (643), Expect = 1e-67,   Method: Composition-based stats.
 Identities = 70/288 (24%), Positives = 125/288 (43%), Gaps = 8/288 (2%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62
           V  +GLG MG+AM+   L+ G+ VTVWNRT SK D+LV  GA    +  E +   +  I 
Sbjct: 24  VTVIGLGPMGQAMADVFLEYGYSVTVWNRTSSKADQLVAKGAIRVSTVNEALAANELVIL 83

Query: 63  MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSG 122
            L+D     S++      L     GK  +++S+   E + K  + +  +G R + G V  
Sbjct: 84  SLTDYNVMYSILEPVSENLF----GKVLVNLSSDTPEKARKAAKWLEDRGARHITGGVQV 139

Query: 123 SKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNM-IMGSMM 181
                   +     +GD+ +FE      +VL     Y G+    A +   + M I  + M
Sbjct: 140 PPSGIGKSESYTYYSGDRVVFEAHRETLEVLTSS-DYRGEDPGLAMLYYQIQMDIFWTAM 198

Query: 182 NAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMF-KGKGPSMNKSSYPPAF-PLKHQQKD 239
            ++   L +A+ +G++++  L        + P F +   P +++  +P     L      
Sbjct: 199 LSYLHALAIANANGITAEQFLPYASAMMSSLPKFVEFYTPRLDEGEHPGDVDRLAMGLAS 258

Query: 240 MRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVKFS 287
           +   +    E  + + + A   E F++    G     F+++IE  K S
Sbjct: 259 VEHVVHTTQEAGIDIALPATVLEVFRRGMKTGHASDSFTSLIEIFKNS 306


>4DLL-A nrPDB
          Length = 320

 Score =  250 bits (637), Expect = 7e-67,   Method: Composition-based stats.
 Identities = 82/280 (29%), Positives = 132/280 (47%), Gaps = 2/280 (0%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61
           ++ FLG G MG  M+  L + G+ + VWNRT ++   L   GA++ E      +     +
Sbjct: 33  KITFLGTGSMGLPMARRLCEAGYALQVWNRTPARAASLAALGATIHEQARAAARDADIVV 92

Query: 62  AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121
           +ML +      V+F + GV   +  G  ++DM+++    +      +   G   ++ PVS
Sbjct: 93  SMLENGAVVQDVLFAQ-GVAAAMKPGSLFLDMASITPREARDHAARLGALGIAHLDTPVS 151

Query: 122 GSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMM 181
           G    AE G L+I+A G  A FE S+P   V G R+ ++G  G+G   KL   MI+G  +
Sbjct: 152 GGTVGAEQGTLVIMAGGKPADFERSLPLLKVFG-RATHVGPHGSGQLTKLANQMIVGITI 210

Query: 182 NAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDMR 241
            A +E L+ A K G     + + +  G   + + +  G  M +  + P   L  Q KDMR
Sbjct: 211 GAVAEALLFATKGGADMAKVKEAITGGFADSRVLQLHGQRMVERDFAPRARLSIQLKDMR 270

Query: 242 LALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVI 281
            ALA   E     P+     + + +    GL DLD S + 
Sbjct: 271 NALATAQEIGFDAPITGLFEQLYAEGVEHGLTDLDQSGLF 310


>4GBJ-A nrPDB
          Length = 297

 Score =  241 bits (616), Expect = 2e-64,   Method: Composition-based stats.
 Identities = 71/281 (25%), Positives = 130/281 (46%), Gaps = 4/281 (1%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61
           ++ FLGLG +G  ++  LL+ G+++ VWNRT SK + L + GA+V E+  + I       
Sbjct: 7   KIAFLGLGNLGTPIAEILLEAGYELVVWNRTASKAEPLTKLGATVVENAIDAITPGGIVF 66

Query: 62  AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121
           ++L+D  A   +   +  ++E++ +   ++ MST+  ETS ++ +     G  +V  P+ 
Sbjct: 67  SVLADDAAVEELFSME--LVEKLGKDGVHVSMSTISPETSRQLAQVHEWYGAHYVGAPIF 124

Query: 122 GSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLG-QVGNGAKMKLIVNMIMGSM 180
              +        I  +G+    E   P  +   K  F  G   G    +KL  N ++   
Sbjct: 125 ARPEAVRAKVGNICLSGNAGAKERIKPIVENFVKGVFDFGDDPGAANVIKLAGNFMIACS 184

Query: 181 MNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPP-AFPLKHQQKD 239
           +    E   +A+K+G+S  ++ ++L       P+F+  G  +  ++Y P AF      KD
Sbjct: 185 LEMMGEAFTMAEKNGISRQSIYEMLTSTLFAAPIFQNYGKLVASNTYEPVAFRFPLGLKD 244

Query: 240 MRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAV 280
           + L L    +    MP A      F    + G  +LD+ A+
Sbjct: 245 INLTLQTASDVNAPMPFADIIRNRFISGLAKGRENLDWGAL 285


>4OQY-A nrPDB
          Length = 290

 Score =  241 bits (615), Expect = 2e-64,   Method: Composition-based stats.
 Identities = 72/288 (25%), Positives = 120/288 (41%), Gaps = 8/288 (2%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60
             V  +GLG MG+AM    L NG +VTVWNRT SK + LV  GA +  +  + +   +  
Sbjct: 4   QSVTVIGLGPMGQAMVNTFLDNGHEVTVWNRTASKAEALVARGAVLAPTVEDALSANELI 63

Query: 61  IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120
           +  L+D  A  +++    G L     GK   ++S+   + + +  +     G + + G V
Sbjct: 64  VLSLTDYDAVYAILEPVTGSL----SGKVIANLSSDTPDKAREAAKWAAKHGAKHLTGGV 119

Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNM-IMGS 179
                     +     +G K +F+       VL   + Y G+    A M     M I  +
Sbjct: 120 QVPPPLIGKPESSTYYSGPKDVFDAHEDTLKVL-TNADYRGEDAGLAAMYYQAQMTIFWT 178

Query: 180 MMNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMF-KGKGPSMNKSSYPPAF-PLKHQQ 237
            M ++ + L L   +G+S+  LL    +     P F +     ++ + YP     L    
Sbjct: 179 TMLSYYQTLALGQANGVSAKELLPYATMMTSMMPHFLELYAQHVDSADYPGDVDRLAMGA 238

Query: 238 KDMRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVK 285
             +   L    +  VS  + AA  E FK     G  +  FS++IE +K
Sbjct: 239 ASVDHVLHTHQDAGVSTVLPAAVAEIFKAGMEKGFAENSFSSLIEVLK 286


>2CVZ-A nrPDB
          Length = 289

 Score =  241 bits (615), Expect = 3e-64,   Method: Composition-based stats.
 Identities = 72/285 (25%), Positives = 128/285 (44%), Gaps = 7/285 (2%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61
           +V F+GLG MG  M+ +L +  F   VWNRT  K     E   S    P E + + +   
Sbjct: 3   KVAFIGLGAMGYPMAGHLARR-FPTLVWNRTFEKALRHQEEFGSEA-VPLERVAEARVIF 60

Query: 62  AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121
             L        V      +   + EG  ++D ++ + E S ++ E +  KG  +++ PVS
Sbjct: 61  TCLPTTREVYEVAEA---LYPYLREGTYWVDATSGEPEASRRLAERLREKGVTYLDAPVS 117

Query: 122 GSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMM 181
           G    AE G L ++  G +   E   P F    K+  ++G VG G  +K I N ++   +
Sbjct: 118 GGTSGAEAGTLTVMLGGPEEAVERVRP-FLAYAKKVVHVGPVGAGHAVKAINNALLAVNL 176

Query: 182 NAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPS-MNKSSYPPAFPLKHQQKDM 240
            A  EGL+   K G+S++  L++++  +  +   +   P  +   ++P  F L    KD+
Sbjct: 177 WAAGEGLLALVKQGVSAEKALEVINASSGRSNATENLIPQRVLTRAFPKTFALGLLVKDL 236

Query: 241 RLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVK 285
            +A+ + D      P+   A E ++ A+     D D    +  ++
Sbjct: 237 GIAMGVLDGEKAPSPLLRLAREVYEMAKRELGPDADHVEALRLLE 281


>5Y8M-A nrPDB
          Length = 295

 Score =  224 bits (571), Expect = 3e-59,   Method: Composition-based stats.
 Identities = 78/290 (26%), Positives = 123/290 (42%), Gaps = 11/290 (3%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62
           + FLGLG MG  MS NL+  G  V  ++   +       HG +V  S  E + +    I 
Sbjct: 5   IAFLGLGNMGAPMSANLVGAGHVVRGFDPAPTAASGAAAHGVAVFRSAPEAVAEADVVIT 64

Query: 63  MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSG 122
           ML           D   VL        +ID ST+    + +++      G   ++ PVSG
Sbjct: 65  MLPTGEVVRRCYTD---VLAAARPATLFIDSSTISVTDAREVHALAESHGMLQLDAPVSG 121

Query: 123 SKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMMN 182
             K A    L  +  GD++    + P  + +  +  + G  G G   K+  NM++     
Sbjct: 122 GVKGAAAATLAFMVGGDESTLRRARPVLEPMAGKIIHCGAAGAGQAAKVCNNMVLAVQQI 181

Query: 183 AFSEGLVLADKSGLSSDTLLDILD------LGAMTNPMFKGKGP-SMNKSSYPPAFPLKH 235
           A +E  VLA+K GLS+ +L D++           TN    G  P S   + + P F    
Sbjct: 182 AIAEAFVLAEKLGLSAQSLFDVITGATGNCWAVHTNCPVPGPVPTSPANNDFKPGFSTAL 241

Query: 236 QQKDMRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVK 285
             KD+ LA+        + P+ + A + + K  +    DLDFSAVI  ++
Sbjct: 242 MNKDLGLAMDAVAATGATAPLGSHAADIYAK-FAADHADLDFSAVIHTLR 290


>3G0O-A nrPDB
          Length = 303

 Score =  221 bits (563), Expect = 3e-58,   Method: Composition-based stats.
 Identities = 69/286 (24%), Positives = 124/286 (43%), Gaps = 2/286 (0%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGA-SVCESPAEVIKKCKY 59
             VG +GLG MG   + + L+ G      +     C  L+  GA     S  E       
Sbjct: 8   FHVGIVGLGSMGMGAARSCLRAGLSTWGADLNPQACANLLAEGACGAAASAREFAGVVDA 67

Query: 60  TIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGP 119
            + ++ +      V+F + GV   +  G   +  ST+ +  + +I  A+T      ++ P
Sbjct: 68  LVILVVNAAQVRQVLFGEDGVAHLMKPGSAVMVSSTISSADAQEIAAALTALNLNMLDAP 127

Query: 120 VSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQ-VGNGAKMKLIVNMIMG 178
           VSG    A  G++ ++A+G +A F    P  D +    + +    G G+ +K+I  ++ G
Sbjct: 128 VSGGAVKAAQGEMTVMASGSEAAFTRLKPVLDAVASNVYRISDTPGAGSTVKIIHQLLAG 187

Query: 179 SMMNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQK 238
             + A +E + LA ++G+  D + D++   A  + MF+ +   +    Y P   +    K
Sbjct: 188 VHIAAAAEAMALAARAGIPLDVMYDVVTHAAGNSWMFENRMQHVVDGDYTPRSAVDIFVK 247

Query: 239 DMRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAV 284
           D+ L           +P+A+ A   F  A + G G  D SAVI+  
Sbjct: 248 DLGLVADTAKALRFPLPLASTALNMFTSASNAGYGKEDDSAVIKIF 293


>4OQZ-A nrPDB
          Length = 289

 Score =  219 bits (558), Expect = 1e-57,   Method: Composition-based stats.
 Identities = 65/288 (22%), Positives = 121/288 (42%), Gaps = 7/288 (2%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60
             V  +GLG MG+AM+   L  G++VT+WNRT S+ D LV  GA +  +P + +   +  
Sbjct: 3   QSVTVIGLGPMGQAMAAAYLDRGYEVTLWNRTASRADALVARGAKLAATPEQALSANELV 62

Query: 61  IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120
           I  L D  A   V+       E+   G+  +++S+   E +      +   GG  + G V
Sbjct: 63  ILSLIDYDAMYGVLEG----AEEAVAGRVLVNLSSDTPEKARAAARRVAELGGTHLTGGV 118

Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNM-IMGS 179
                      +    +G +A +++   A +V+  ++ Y G+    A +   +NM +   
Sbjct: 119 LSPPPGIGSPDMSTFYSGPRAAYDQHRAALEVITGKTDYRGEDPGLAALMYQLNMVVFWP 178

Query: 180 MMNAFSEGLVLADKSGLSSDTLLDILDLG-AMTNPMFKGKGPSMNKSSYPPAF-PLKHQQ 237
            M ++ + + LAD  GL++  +   +    A            ++  ++      L    
Sbjct: 179 AMLSYWQAVALADAHGLTAADIAPYVSENFAGMGQFIDFYAARIDAGNHAGDVDRLSMGV 238

Query: 238 KDMRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVK 285
             M   +    ++ V      A  +AF +    G G   FS+VI+ +K
Sbjct: 239 ASMEHVVHTNADSGVDTAFPRAVLDAFHRGADAGFGADSFSSVIKLMK 286


>3Q3C-A nrPDB
          Length = 299

 Score =  218 bits (556), Expect = 2e-57,   Method: Composition-based stats.
 Identities = 78/290 (26%), Positives = 130/290 (44%), Gaps = 7/290 (2%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61
           ++ F+GLG MG  M+ NLLK G+ + V++   S  D LV  GAS   S  + ++     I
Sbjct: 4   QIAFIGLGHMGAPMATNLLKAGYLLNVFDLVQSAVDGLVAAGASAARSARDAVQGADVVI 63

Query: 62  AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121
           +ML        +  D  G+L  I  G   ++ ST+   ++ KI+ A   +G   ++ PVS
Sbjct: 64  SMLPASQHVEGLYLDDDGLLAHIAPGTLVLECSTIAPTSARKIHAAARERGLAMLDAPVS 123

Query: 122 GSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMM 181
           G    A  G L  +  GD    E++ P F+ +G+  F+ G  G G   K+  N ++  +M
Sbjct: 124 GGTAGAAAGTLTFMVGGDAEALEKARPLFEAMGRNIFHAGPDGAGQVAKVCNNQLLAVLM 183

Query: 182 NAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGP-------SMNKSSYPPAFPLK 234
              +E + L   +GL +  L +I+   +  N   +   P       +     Y   F  +
Sbjct: 184 IGTAEAMALGVANGLEAKVLAEIMRRSSGGNWALEVYNPWPGVMENAPASRDYSGGFMAQ 243

Query: 235 HQQKDMRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAV 284
              KD+ LA      +A S P+ + A   ++     G  + DFS V +  
Sbjct: 244 LMAKDLGLAQEAAQASASSTPMGSLALSLYRLLLKQGYAERDFSVVQKLF 293


>5U5G-A nrPDB
          Length = 295

 Score =  212 bits (540), Expect = 1e-55,   Method: Composition-based stats.
 Identities = 61/287 (21%), Positives = 108/287 (37%), Gaps = 2/287 (0%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62
           VGF+GLG MG+A+   LL +   V V NR+  K D+L+  GA        + +  +    
Sbjct: 5   VGFIGLGRMGQAICRRLLASQMPVHVHNRSREKADDLIRQGAVWAPDIVALTRAARVLFV 64

Query: 63  MLSDPCAALSVVFDKG-GVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121
             +   A          G+L  +  G   +D+ST+  ET+  ++ A   +G  ++E PVS
Sbjct: 65  CTAGSEAVQDFYHAPDRGLLACLEVGDIVVDLSTIAPETAEGLHAAFAQQGADYIECPVS 124

Query: 122 GSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMM 181
           G  + A  G L  + +G    +    P  +V      Y+ + G   ++K++ N+     +
Sbjct: 125 GGVEGALAGILSAIVSGRPEAYGLIRPLLEVFCATVTYVPEPGKAQRLKILNNLAESINL 184

Query: 182 NAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDMR 241
               E +      GL   ++ D+       +                    L  + KD+ 
Sbjct: 185 AGAIEVISQGLSQGLDLKSMADVFTSCRGRSAYMDVALGYALSGGASSNVSLGVRCKDLE 244

Query: 242 LALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVKFSR 288
           LA         S P +  A   F   R     + D       +  ++
Sbjct: 245 LARRRL-PQDQSYPFSTLAMTTFDTVRQACGEESDQCQYFSVLSHNK 290


>5A9T-A nrPDB
          Length = 290

 Score =  211 bits (536), Expect = 4e-55,   Method: Composition-based stats.
 Identities = 60/289 (20%), Positives = 113/289 (39%), Gaps = 8/289 (2%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60
           + V   GLG MG A++  LL  G  VTVWNR+  K   LV  GA   +   + +   +  
Sbjct: 6   LPVTVAGLGPMGSALAAALLDRGHDVTVWNRSPGKAAPLVAKGARQADDIVDAVSASRLL 65

Query: 61  IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120
           +  L+D  A  S +    G   +   G+  +++++   + + +        G  +++G +
Sbjct: 66  VVCLADYDALYSAL----GPAREALRGRVVVNLNSGTPKEANEALRWAERHGTGYLDGAI 121

Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 180
                       + L +G   +FEE       LG       + G        +  +M S 
Sbjct: 122 MVPPAMVGHPGSVFLYSGSAEVFEEYKETLAGLGDPVHLGTEAGLAVLYNTALLSMMYSS 181

Query: 181 MNAFSEGLVLADKSGLSSDTLLDILD---LGAMTNPMFKGKGPSMNKSSYPPA-FPLKHQ 236
           MN F     L   +G+ +     +     L A+   + K + P++++  YP     L+  
Sbjct: 182 MNGFLHAAALVGSAGVPAAEFTKLAVDWFLPAVIGQIIKAEAPTIDEGVYPGDAGSLEMN 241

Query: 237 QKDMRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVK 285
              ++  +    E  V   +     E   +A + G G+  + +VIE  +
Sbjct: 242 VTTLKHIIGTSQEQGVDTEIPVRNKELLDRAVAAGFGESSYYSVIELWR 290


>4D3S-A nrPDB
          Length = 293

 Score =  210 bits (534), Expect = 6e-55,   Method: Composition-based stats.
 Identities = 65/284 (22%), Positives = 117/284 (41%), Gaps = 5/284 (1%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61
            V  +GLG MG+AM+  LL+ G+++TVWNRT +K + L E GA+V +SPAE ++     +
Sbjct: 10  PVTLIGLGPMGQAMAGALLEAGYELTVWNRTKAKAEALAERGAAVADSPAEALRAGGPVL 69

Query: 62  AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121
             L++      V+      L    +G+  +++ +     S        G G R+V G V 
Sbjct: 70  LSLTEHAVMYRVLEGAESDL----KGRTILNLGSDTPAASRAAAAWAEGHGARYVTGGVM 125

Query: 122 GSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMM 181
                     +    +GD+A FEE+    +VL    F     G       I+  +  + M
Sbjct: 126 SPAPGIGSSSVFSFYSGDRAAFEENKALLEVLTATDFRGEDPGLAQVYYQILLDLFWTTM 185

Query: 182 NAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAF-PLKHQQKDM 240
             +   L +A   G+   T+   L  G      F+G   ++ +  +P     +      M
Sbjct: 186 TGYLHALAVARAEGVPVGTITPYLIEGNDMAMFFEGTSAAVAEGRFPGDEDRISMDAASM 245

Query: 241 RLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAV 284
              +    +  V   +  A    F++    G  +  F+ ++  +
Sbjct: 246 EHVVQTSRDAGVDTALPEAVLSLFRRGLDAGFAESSFARLVTLM 289


>3ZHB-A nrPDB
          Length = 309

 Score =  208 bits (529), Expect = 2e-54,   Method: Composition-based stats.
 Identities = 62/287 (21%), Positives = 120/287 (41%), Gaps = 6/287 (2%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61
            V  +GLG+MG+A++   L  G   TVWNRT +K + LV  GA    S AE +      +
Sbjct: 21  PVTVIGLGLMGQALAGAFLGAGHPTTVWNRTAAKAEPLVARGAKSAGSVAEAVAASPLVV 80

Query: 62  AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121
             +SD  A  +++    G      +G+  +++++  +  + +      G+G  +++G + 
Sbjct: 81  VCVSDYDAVHALLDPLDGT---ALQGRTLVNLTSGTSAQARERAAWADGRGADYLDGAIL 137

Query: 122 GSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLG-QVGNGAKMKLIVNMIMGSM 180
                      ++L +G ++ F+    A   LG  + YLG   G  +       ++M S+
Sbjct: 138 AGPAAIGTADAVVLLSGPRSAFDPHASALGGLGAGTTYLGADHGLASLYDAAGLVMMWSI 197

Query: 181 MNAFSEGLVLADKSGLSSDTLLDILDLGAMT-NPMFKGKGPSMNKSSYP-PAFPLKHQQK 238
           +N F +G  L   +G+ + T    +  G  T      G    ++  +YP     +     
Sbjct: 198 LNGFLQGAALLGTAGVDATTFAPFITQGIGTVADWLPGYARQIDDGAYPADDAAIDTHLA 257

Query: 239 DMRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVK 285
            M   +   +   V+  +         +A + G G   + A+IE  +
Sbjct: 258 TMEHLIHESEFLGVNAELPRFIKALADRAVADGHGGSGYPALIEQFR 304


>2W8Z-A nrPDB
          Length = 470

 Score =  203 bits (516), Expect = 7e-53,   Method: Composition-based stats.
 Identities = 58/294 (19%), Positives = 109/294 (37%), Gaps = 29/294 (9%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEH-------GASVCESPAEVI 54
           ++G +GL +MGK +++N+   G+ V V+NR   K DE ++        G    E     +
Sbjct: 6   QIGVIGLAVMGKNLALNIESKGYSVAVYNRLREKTDEFLQEAKGKNIVGTYSIEEFVNAL 65

Query: 55  KKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGR 114
           +K +  + M+       + +         + +G   ID      + + + N+ +   G  
Sbjct: 66  EKPRKILLMVKAGAPTDATIEQLK---PHLEKGDIVIDGGNTYFKDTQRRNKELAELGIH 122

Query: 115 FVEGPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRS------FYLGQVGNGAK 168
           F+   VSG ++ A  G   I+  G K   E   P F+ +  +        Y+G  G G  
Sbjct: 123 FIGTGVSGGEEGALKGP-SIMPGGQKEAHELVRPIFEAIAAKVDGEPCTTYIGPDGAGHY 181

Query: 169 MKLIVNMIMGSMMNAFSEGLVLAD-KSGLSSDTLLDIL---DLGAMTNPMFKGKGPSMNK 224
           +K++ N I    M   +E   L     G+ +  L ++    + G + + + +       K
Sbjct: 182 VKMVHNGIEYGDMQLIAEAYFLLKHVLGMDAAELHEVFADWNKGELNSYLIEITADIFTK 241

Query: 225 SSYPPAFPLKHQQKDMRLALALGD-------ENAVSMP-VAAAANEAFKKARSL 270
                  PL     D       G        +  V +P +  +    F  A   
Sbjct: 242 IDEETGKPLVDVILDKAGQKGTGKWTSQNALDLGVPLPIITESVFARFLSAMKD 295


>5G6R-A nrPDB
          Length = 295

 Score =  201 bits (512), Expect = 2e-52,   Method: Composition-based stats.
 Identities = 69/294 (23%), Positives = 119/294 (40%), Gaps = 12/294 (4%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61
            +G  GLG MG A++   L++G+K +VWNRT +K   LVE GA +  + +E +      I
Sbjct: 4   HIGIFGLGAMGTALAAKYLEHGYKTSVWNRTTAKAIPLVEQGAKLASTISEGVNANDLII 63

Query: 62  AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121
             L +       + D    L      K  ++++      + K+ + +T  G R++ G + 
Sbjct: 64  ICLLNNQVVEDALRDALQTL----PSKTIVNLTNGTPNQARKLADFVTSHGARYIHGGIM 119

Query: 122 GSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLG-QVGNGAKMKLIVNMIMGSM 180
                      ++L +G+     +SI +   L   S YLG   G+ +   L +   M  +
Sbjct: 120 AVPTMIGSPHAVLLYSGESLELFQSIESHLSLLGMSKYLGTDAGSASLHDLALLSGMYGL 179

Query: 181 MNAFSEGLVLADKSGLSSDT----LLDILD-LGAMTNPMFKGKGPSMNKSSYPP-AFPLK 234
            + F   + L  KSG  + T    LL +L    +            ++   Y      L 
Sbjct: 180 FSGFLHAVALI-KSGQDTSTTATGLLPLLTPWLSAMTGYLSSIAKQIDDGDYATQGSNLG 238

Query: 235 HQQKDMRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVKFSR 288
            Q   +   +  G+E  VS  +        ++A   G G  D SA+IE  K  +
Sbjct: 239 MQLAGVENIIRAGEEQRVSSQMILPIKALIEQAVGEGHGGEDLSALIEYFKVGK 292


>5OCM-A nrPDB
          Length = 291

 Score =  191 bits (484), Expect = 4e-49,   Method: Composition-based stats.
 Identities = 61/287 (21%), Positives = 121/287 (42%), Gaps = 7/287 (2%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61
           +V  LGLG+MG+A++   LK+G   TVWNR+  K  +L E GA +  S  +  +     +
Sbjct: 5   DVTVLGLGLMGQALAGAFLKDGHATTVWNRSEGKAGQLAEQGAVLASSARDAAEASPLVV 64

Query: 62  AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121
             +SD  A  +V+   G VL     G+  +++++  +E +    E    +G  +++G + 
Sbjct: 65  VCVSDHAAVRAVLDPLGDVLA----GRVLVNLTSGTSEQARATAEWAAERGITYLDGAIM 120

Query: 122 GSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMK-LIVNMIMGSM 180
              +        +L +G +A +E   P    LG  + YLG     + +  + +  IM   
Sbjct: 121 AIPQVVGTADAFLLYSGPEAAYEAHEPTLRSLGAGTTYLGADHGLSSLYDVALLGIMWGT 180

Query: 181 MNAFSEGLVLADKSGLSSDTLLDILD-LGAMTNPMFKGKGPSMNKSSYPP-AFPLKHQQK 238
           +N+F  G  L   + + + T     +                +++ +YP     +     
Sbjct: 181 LNSFLHGAALLGTAKVEATTFAPFANRWIEAVTGFVSAYAGQVDQGAYPALDATIDTHVA 240

Query: 239 DMRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVK 285
            +   +   +   V+  +         +A + G G L ++A+IE  +
Sbjct: 241 TVDHLIHESEAAGVNTELPRLVRTLADRALAGGQGGLGYAAMIEQFR 287


>3QHA-A nrPDB
          Length = 296

 Score =  191 bits (484), Expect = 4e-49,   Method: Composition-based stats.
 Identities = 74/287 (25%), Positives = 127/287 (44%), Gaps = 18/287 (6%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60
           +++G++GLG MG  M+  + +    VTV++  +     L E GA++ +S A+V       
Sbjct: 16  LKLGYIGLGNMGAPMATRMTEWPGGVTVYDIRIEAMTPLAEAGATLADSVADVAAADLIH 75

Query: 61  IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120
           I +L D      VV +  G       G      ST+   T++++   +  +    V+ PV
Sbjct: 76  ITVLDD-AQVREVVGELAG---HAKPGTVIAIHSTISDTTAVELARDLKARDIHIVDAPV 131

Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 180
           SG    A  G+L  +   D+ ++E   PAF        + G+ G G +MKL  NM+  + 
Sbjct: 132 SGGAAAAARGELATMVGADREVYERIKPAFKHWAAVVIHAGEPGAGTRMKLARNMLTFTS 191

Query: 181 MNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSY----PPAF----- 231
             A  E + LA+ +GL    L  ++     T+ +  G G  M + +     P  F     
Sbjct: 192 YAAACEAMKLAEAAGLDLQALGRVVR---HTDALTGGPGAIMVRDNMKDLEPDNFLYQPF 248

Query: 232 --PLKHQQKDMRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLD 276
                  +KD+ LALALG+  +V +P+A  A E       +   + +
Sbjct: 249 LHTRGLGEKDLSLALALGEAVSVDLPLARLAYEGLAAGLGVPHKEKE 295


>2IZ1-A nrPDB
          Length = 474

 Score =  189 bits (479), Expect = 2e-48,   Method: Composition-based stats.
 Identities = 53/279 (18%), Positives = 109/279 (39%), Gaps = 30/279 (10%)

Query: 4   GFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEH-------GASVCESPAEVIKK 56
           G +G+ +MGK +++N+   G+ V ++NRT SK +E+ +             E     ++K
Sbjct: 9   GVVGMAVMGKNLALNVESRGYTVAIYNRTTSKTEEVFKEHQDKNLVFTKTLEEFVGSLEK 68

Query: 57  CKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFV 116
            +  + M+    A  + +     +L  +  G   ID        +++ N  +   G  F+
Sbjct: 69  PRRIMLMVQAGAATDATI---KSLLPLLDIGDILIDGGNTHFPDTMRRNAELADSGINFI 125

Query: 117 EGPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKR--------SFYLGQVGNGAK 168
              VSG +K A  G   ++  G K  ++   P F+ +  +          Y+G  G G  
Sbjct: 126 GTGVSGGEKGALLGP-SMMPGGQKEAYDLVAPIFEQIAAKAPQDGKPCVAYMGANGAGHY 184

Query: 169 MKLIVNMIMGSMMNAFSEGLVLADK-SGLSS---DTLLDILDLGAMTNPMFKGKGPSMNK 224
           +K++ N I    M   +E   L  +  GLS+     + +  + G + + + +     + +
Sbjct: 185 VKMVHNGIEYGDMQLIAESYDLLKRILGLSNAEIQAIFEEWNEGELDSYLIEITKEVLKR 244

Query: 225 SSYPPAFPLKHQQKDMRLALALGD-------ENAVSMPV 256
                   +  +  D       G        +  V +P+
Sbjct: 245 KDDEGEGYIVDKILDKAGNKGTGKWTSESALDLGVPLPL 283


>2ZYA-A nrPDB
          Length = 480

 Score =  186 bits (471), Expect = 1e-47,   Method: Composition-based stats.
 Identities = 48/273 (17%), Positives = 101/273 (36%), Gaps = 19/273 (6%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHG-------ASVCESPAEV 53
            ++G +G+ +MG+ +++N+   G+ V+++NR+  K +E++              +   E 
Sbjct: 16  QQIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVIAENPGKKLVPYYTVKEFVES 75

Query: 54  IKKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGG 113
           ++  +  + M+       + +     +   + +G   ID      + +++ N  ++ +G 
Sbjct: 76  LETPRRILLMVKAGAGTDAAI---DSLKPYLDKGDIIIDGGNTFFQDTIRRNRELSAEGF 132

Query: 114 RFVEGPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKR-------SFYLGQVGNG 166
            F+   VSG ++ A  G   I+  G K  +E   P    +            Y+G  G G
Sbjct: 133 NFIGTGVSGGEEGALKGP-SIMPGGQKEAYELVAPILTKIAAVAEDGEPCVTYIGADGAG 191

Query: 167 AKMKLIVNMIMGSMMNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSS 226
             +K++ N I    M   +E   L  K GL+              N         + K  
Sbjct: 192 HYVKMVHNGIEYGDMQLIAEAYSLL-KGGLNLTNEELAQTFTEWNNGELSSYLIDITKDI 250

Query: 227 YPPAFPLKHQQKDMRLALALGDENAVSMPVAAA 259
           +       +   D+ L  A           +A 
Sbjct: 251 FTKKDEDGNYLVDVILDEAANKGTGKWTSQSAL 283


>3L6D-A nrPDB
          Length = 306

 Score =  186 bits (471), Expect = 1e-47,   Method: Composition-based stats.
 Identities = 62/292 (21%), Positives = 110/292 (37%), Gaps = 6/292 (2%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60
            +V  +GLG MG  M+  LLK G +V +WNR+  K   LV  GA +CES    +     T
Sbjct: 10  FDVSVIGLGAMGTIMAQVLLKQGKRVAIWNRSPGKAAALVAAGAHLCESVKAALSASPAT 69

Query: 61  IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120
           I +L D  A   V+   G  + +    +  +D +T   +  L +   +   GG +V+G +
Sbjct: 70  IFVLLDNHATHEVLGMPG--VARALAHRTIVDYTTNAQDEGLALQGLVNQAGGHYVKGMI 127

Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 180
               +     +   +  GD+  FE+     + L   + +L           +++    + 
Sbjct: 128 VAYPRNVGHRESHSIHTGDREAFEQHRALLEGLAGHTVFLPWD-EALAFATVLHAHAFAA 186

Query: 181 MNAFSEGLVLADKSGLSSDTLLDIL--DLGAMTNPMFKGKGPSMNKSSYPPA-FPLKHQQ 237
           M  F E +   D+ GL       +L            +     +    +      L    
Sbjct: 187 MVTFFEAVGAGDRFGLPVSKTARLLLETSRFFVADALEEAVRRLETQDFKGDQARLDVHA 246

Query: 238 KDMRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVKFSRE 289
                         V  PV  A  +  ++A ++G GD D +A  ++    +E
Sbjct: 247 DAFAHIAQSLHAQGVWTPVFDAVCQVVQRAAAMGYGDQDIAATTKSFAREQE 298


>6FQY-A nrPDB
          Length = 468

 Score =  169 bits (428), Expect = 1e-42,   Method: Composition-based stats.
 Identities = 57/287 (19%), Positives = 106/287 (36%), Gaps = 30/287 (10%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDE---------LVEHGASVCESPAE 52
           ++G +GL +MG+ +S+N+   GFK+ V+NRT  + +E         LV +G    E    
Sbjct: 3   DIGLIGLAVMGQNLSLNISSKGFKIGVYNRTYERTEETMKRAKEENLVVYGYKTVEELIN 62

Query: 53  VIKKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKG 112
            +KK +  I ++    A      +   +L+   +G   ID        S +  +    K 
Sbjct: 63  NLKKPRKVILLIKAGPAVDE---NISNILKHFEKGDIIIDGGNEWYINSERRIKLCKEKD 119

Query: 113 GRFVEGPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKR------SFYLGQVGNG 166
             ++   VSG +  A  G    +  G K  ++      +    +        Y+G   +G
Sbjct: 120 VEYLAMGVSGGEAGARYG-CSFMPGGSKYAYDCVKEILEKCSAQVGNSPCVTYIGPGSSG 178

Query: 167 AKMKLIVNMIMGSMMNAFSEGLVLADK-SGLSSDTLLDIL---DLGAMTNPMFKGKGPSM 222
             +K++ N I    M   SE  V+        +  L ++    + G + + + +     +
Sbjct: 179 NYVKMVHNGIEYGDMQLISESYVIMKHILKYDNQKLSEVFNKWNEGILNSYLIEITANIL 238

Query: 223 NKSSYPPAFPLKHQQKDMRLALALGD-------ENAVSMPVAAAANE 262
            K        L     D+  A   G        E  +  P   AA +
Sbjct: 239 AKKDDLTNNYLVDMILDIAGAKGTGKWTMLEATERGIPCPTMCAALD 285


>6EOI-A nrPDB
          Length = 298

 Score =  169 bits (427), Expect = 2e-42,   Method: Composition-based stats.
 Identities = 62/292 (21%), Positives = 103/292 (35%), Gaps = 10/292 (3%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61
           ++   GLG MG AM+   LK G   TVWNRT +K + LVE GA +  +    I      I
Sbjct: 9   KLTIFGLGAMGTAMATQFLKQGHTPTVWNRTAAKANPLVEQGAHLAATIPAAIAASPLLI 68

Query: 62  AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121
             L D  A    +            GK  ++++      + ++    + +G R+  G + 
Sbjct: 69  FCLLDNAAVEQTLAAG----PPSLAGKTILNLTNGTPSQARRLATLASARGARYFHGGIM 124

Query: 122 GSKKPAEDGQLIILA--AGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGS 179
            +         +IL    G    +        VLG   +     G+ +   L +   M  
Sbjct: 125 ATPDMIGAPHAVILYSGGGSAETYASVEGVLAVLGSGKYLGDDAGSASLHDLALLSGMYG 184

Query: 180 MMNAFSEGLVLADK--SGLSSDTLLDILD-LGAMTNPMFKGKGPSMNKSSY-PPAFPLKH 235
           +   F     L      G+S+   L +L                 ++   Y      L+ 
Sbjct: 185 LFAGFLHATALVRSEGEGVSATEFLGLLAPWLQAMTGYLGLLARQIDDGVYTAQTSNLEM 244

Query: 236 QQKDMRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVKFS 287
           Q   +  A A   E  VS  V        ++A   G G  D S++I+  + +
Sbjct: 245 QLVALENACAASREQGVSAEVMLPLKGLVERAVREGRGGHDISSLIDYFRNA 296


>4E21-A nrPDB
          Length = 358

 Score =  168 bits (426), Expect = 2e-42,   Method: Composition-based stats.
 Identities = 54/244 (22%), Positives = 90/244 (36%), Gaps = 34/244 (13%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKK-CKY 59
           M++G +GLG MG  M   L K G +  V++  ++    L   G +   S  E   K  K 
Sbjct: 23  MQIGMIGLGRMGADMVRRLRKGGHECVVYDLNVNAVQALEREGIAGARSIEEFCAKLVKP 82

Query: 60  TIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGP 119
            +  L  P A +  +  +   L  +      ID      +  ++  + +  +G  +V+  
Sbjct: 83  RVVWLMVPAAVVDSMLQRMTPL--LAANDIVIDGGNSHYQDDIRRADQMRAQGITYVDVG 140

Query: 120 VSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRS--------------------FY 159
            SG     E G   ++  G+K   E   P F  L                         +
Sbjct: 141 TSGGIFGLERGYC-LMIGGEKQAVERLDPVFRTLAPGIGAAPRTPGREKREGTAELGYLH 199

Query: 160 LGQVGNGAKMKLIVNMIMGSMMNAFSEGLVL-----ADKSGLSSDTLLDILDLGAMTNPM 214
            G  G G  +K++ N I   +M A++EGL +     A K G  +D      +   + NP 
Sbjct: 200 CGPSGAGHFVKMVHNGIEYGLMAAYAEGLNILHHANAGKEGQGADA-----ETAPLRNPD 254

Query: 215 FKGK 218
           F   
Sbjct: 255 FYRY 258


>1PGJ-A nrPDB
          Length = 478

 Score =  159 bits (403), Expect = 9e-40,   Method: Composition-based stats.
 Identities = 53/276 (19%), Positives = 104/276 (37%), Gaps = 32/276 (11%)

Query: 13  KAMSMNLLKNGFKVTVWNRTLSKCDELVEHGAS-----------VCESPAEVIKKCKYTI 61
             +++N+ + GFKV V+NRT SK +E ++  AS             E+ A  +KK +  +
Sbjct: 14  ANLALNIAEKGFKVAVFNRTYSKSEEFMKANASAPFAGNLKAFETMEAFAASLKKPRKAL 73

Query: 62  AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121
            ++    A  S +     V E   +G   +D      +   +  + +   G RF+   +S
Sbjct: 74  ILVQAGAATDSTIEQLKKVFE---KGDILVDTGNAHFKDQGRRAQQLEAAGLRFLGMGIS 130

Query: 122 GSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKR-------SFYLGQVGNGAKMKLIVN 174
           G ++ A  G       G  +++EE  P  +    +           G  G G+ +K+  N
Sbjct: 131 GGEEGARKGP-AFFPGGTLSVWEEIRPIVEAAAAKADDGRPCVTMNGSGGAGSCVKMYHN 189

Query: 175 MIMGSMMNAFSEGLVLADKSGLSSDTLLDILD----LGAMTNPMFKGKGPSMNKSSYPPA 230
               +++  + E   +    GL++D +  +L+       + + M      +        +
Sbjct: 190 SGEYAILQIWGEVFDILRAMGLNNDEVAAVLEDWKSKNFLKSYMLDISIAAARAKDKDGS 249

Query: 231 FPLKH-----QQKDMRL-ALALGDENAVSMPVAAAA 260
           +  +H       K   L +     E  V  P    A
Sbjct: 250 YLTEHVMDRIGSKGTGLWSAQEALEIGVPAPSLNMA 285


>1PGO-A nrPDB
          Length = 482

 Score =  146 bits (369), Expect = 8e-36,   Method: Composition-based stats.
 Identities = 45/222 (20%), Positives = 86/222 (38%), Gaps = 20/222 (9%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVE--------HGASVCESPAEV 53
           ++  +GL +MG+ + +N+  +GF V  +NRT+SK D+ +          GA   E     
Sbjct: 4   DIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVLGAHSLEEMVSK 63

Query: 54  IKKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGG 113
           +KK +  I ++    A  + +     +L+         +    +   +++    +  KG 
Sbjct: 64  LKKPRRIILLVKAGQAVDNFIEKLVPLLDIGDIIIDGGNS---EYRDTMRRCRDLKDKGI 120

Query: 114 RFVEGPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRS-------FYLGQVGNG 166
            FV   VSG +  A  G   ++  G+K  +      F  +  +         ++G  G G
Sbjct: 121 LFVGSGVSGGEDGARYGP-SLMPGGNKEAWPHIKAIFQGIAAKVGTGEPCCDWVGDDGAG 179

Query: 167 AKMKLIVNMIMGSMMNAFSEGLVLAD-KSGLSSDTLLDILDL 207
             +K++ N I    M    E   L     GL    +    + 
Sbjct: 180 HFVKMVHNGIEYGDMQLICEAYHLMKDVLGLGHKEMAKAFEE 221


>4GWK-A nrPDB
          Length = 484

 Score =  140 bits (354), Expect = 4e-34,   Method: Composition-based stats.
 Identities = 46/221 (20%), Positives = 90/221 (40%), Gaps = 20/221 (9%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEH--------GASVCESPAEV 53
           ++  +GL +MG+ + +N+  +GF V  +NRT+SK D+ + +        GA   +     
Sbjct: 6   DIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKEMVSK 65

Query: 54  IKKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGG 113
           +KK +  I ++    A    +     ++  +  G   ID    +   + +    +  KG 
Sbjct: 66  LKKPRRIILLVKAGQAVDDFIEK---LVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKGI 122

Query: 114 RFVEGPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRS-------FYLGQVGNG 166
            FV   VSG ++ A  G   ++  G+K  +      F  +  +         ++G  G G
Sbjct: 123 LFVGSGVSGGEEGARYGP-SLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGAG 181

Query: 167 AKMKLIVNMIMGSMMNAFSEGLVLAD-KSGLSSDTLLDILD 206
             +K++ N I    M    E   L     G++ D +    +
Sbjct: 182 HFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFE 222


>2P4Q-A nrPDB
          Length = 497

 Score =  140 bits (354), Expect = 4e-34,   Method: Composition-based stats.
 Identities = 57/292 (19%), Positives = 110/292 (37%), Gaps = 28/292 (9%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEH--------GASVCESPAEV 53
           + G +GL +MG+ + +N   +GF V  +NRT SK D  + +        GA+  E     
Sbjct: 12  DFGLIGLAVMGQNLILNAADHGFTVCAYNRTQSKVDHFLANEAKGKSIIGATSIEDFISK 71

Query: 54  IKKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGG 113
           +K+ +  + ++       +++     ++  + +G   ID        S +  E +  KG 
Sbjct: 72  LKRPRKVMLLVKAGAPVDALINQ---IVPLLEKGDIIIDGGNSHFPDSNRRYEELKKKGI 128

Query: 114 RFVEGPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSF------YLGQVGNGA 167
            FV   VSG ++ A  G   ++  G +  +      F  +  +S       ++G  G G 
Sbjct: 129 LFVGSGVSGGEEGARYGP-SLMPGGSEEAWPHIKNIFQSISAKSDGEPCCEWVGPAGAGH 187

Query: 168 KMKLIVNMIMGSMMNAFSEGLVLADK-SGLSSDTLLDIL---DLGAMTNPMFKGKGPSMN 223
            +K++ N I    M    E   +  +  G +   + D+    + G + + + +     + 
Sbjct: 188 YVKMVHNGIEYGDMQLICEAYDIMKRLGGFTDKEISDVFAKWNNGVLDSFLVEI-TRDIL 246

Query: 224 KSSYPPAFPLKHQQKDMRLALALGD-----ENAVSMPVAAAANEAFKKARSL 270
           K       PL  +  D       G         + MPV       F +  S 
Sbjct: 247 KFDDVDGKPLVEKIMDTAGQKGTGKWTAINALDLGMPVTLIGEAVFARCLSA 298


>4R16-A nrPDB
          Length = 418

 Score = 66.7 bits (161), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 49/297 (16%), Positives = 95/297 (31%), Gaps = 43/297 (14%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLS-------------------KCDELVE 41
           M +  LGLG +G   ++    +G+ V  ++                       +  E++ 
Sbjct: 1   MRIAVLGLGYIGLPTAIMFASSGYDVVGYDIRSEVIKKINSGVAHIIEPEIDRRLKEVLS 60

Query: 42  HGASVCESPAEVIKKCKYTIAMLSDPCAALSVVF-----DKGGVLEQICEGKGYIDMSTV 96
            G        E +K     I  +  P +               V E +  G   I  ST+
Sbjct: 61  LGKLKVTDRVEDLKGSNVFIICVQTPLSGDDPDLSYLERAIRTVAEVMDRGALVIIESTI 120

Query: 97  DAETSLKINEAITG-----KGGRF--VEGP---VSGSKKPAEDGQLIILAAGDKALFEES 146
              T+ K+   +       +G  F     P   + G           I+    +     +
Sbjct: 121 PPGTTEKMARLLENLTGLREGVDFYVAHAPERVMPGRIFKELVYNSRIIGGVSEKAANLA 180

Query: 147 IPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMMNAFSEGLVLADKSGLSSDTLLDILD 206
              +    K   +L        +KL+ N      +   +E  +LA + G++   + + ++
Sbjct: 181 EKLYRSFVKGRIFLTNATTAEMVKLMENTFRDVNIALANEFALLAHQYGVN---VYEAIE 237

Query: 207 LGAMTNPMFKGKGPSMNKSSY----PPAFPLKHQQKDMRLALALGDENAVSMPVAAA 259
           L   T+P  K   P +    +     P   L + ++D  L + +       MP  AA
Sbjct: 238 LAN-THPRVKIHTPGIGVGGHCLPKDPYLLLSNAKEDFGL-IRIARRINERMPAFAA 292


>2Y0D-A nrPDB
          Length = 478

 Score = 58.6 bits (140), Expect = 3e-09,   Method: Composition-based stats.
 Identities = 48/309 (15%), Positives = 91/309 (29%), Gaps = 57/309 (18%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCE------------ 48
           M +  +G G +G      L   G  V   +   +K D L   G  + E            
Sbjct: 9   MNLTIIGSGKVGLVTGACLADIGHDVFCLDVDQAKIDILNNGGVPIHEPGLKEVIARNRS 68

Query: 49  --------SPAEVIKKCKYTIAMLSDP------CAALSVVFDKGGVLEQICEGKGYIDMS 94
                        +         +  P           V+     +   +   K  +D S
Sbjct: 69  AGRLRFSTDIEAAVAHGDVQFIAVGTPPDEDGSADLQYVLAAARNIGRYMTGFKVIVDKS 128

Query: 95  TVDAETSLK----INEAITGKGGRFVEGPVSGSK---KPAE----DGQLIILAAGDKAL- 142
           TV   T+ +    + E +  +GG  +   VS  +   + A          I+   D  + 
Sbjct: 129 TVPVGTAERVRAAVAEELAKRGGDQMFSVVSNPEFLKEGAAVDDFTRPDRIVIGCDDDVP 188

Query: 143 FEESIPAFDVLGK-------RSFYLGQVGNGAKMKLIVNMIMGSMMNAFSEGLVLADKSG 195
            E +      L         R+ Y+  V +    K   N ++ + ++  +E   LAD+ G
Sbjct: 189 GERARELMKKLYAPFNRNHERTLYM-DVRSAEFTKYAANAMLATRISFMNELANLADRFG 247

Query: 196 LSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPP-AFPLKHQQKDMRLALALGDENAVSM 254
              + +   +         F           Y    +      KD+   +   DE+  S+
Sbjct: 248 ADIEAVRRGIGSDPRIGYHF----------LYAGCGYGGSCFPKDVEALIRTADEHGQSL 297

Query: 255 PVAAAANEA 263
            +  A +  
Sbjct: 298 QILKAVSSV 306


>2F1K-A nrPDB
          Length = 279

 Score = 55.9 bits (133), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 34/262 (12%), Positives = 84/262 (32%), Gaps = 47/262 (17%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHG-ASVCESPAEVIKKCKY 59
           M++G +GLG++G +++ +L + G  +   +R  S C++ VE            +++  K 
Sbjct: 1   MKIGVVGLGLIGASLAGDLRRRGHYLIGVSRQQSTCEKAVERQLVDEAGQDLSLLQTAKI 60

Query: 60  TIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGP 119
                        ++     ++  +       D+++V       I E  +     F+ G 
Sbjct: 61  IFLCTP----IQLILPTLEKLIPHLSPTAIVTDVASV----KTAIAEPASQLWSGFIGGH 112

Query: 120 VSGSK--KPAEDGQLIILAAG----------DKALFEESIPAFDVLGKRSFYLGQVGNGA 167
                  +  +  +  +              D           + LG + +      +  
Sbjct: 113 PMAGTAAQGIDGAEENLFVNAPYVLTPTEYTDPEQLACLRSVLEPLGVKIYLCTPADHDQ 172

Query: 168 KMKLIVN---MIMGSMMNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNK 224
            +  I +   M+  +++ A +      +K G       DIL L             ++  
Sbjct: 173 AVAWISHLPVMVSAALIQACA-----GEKDG-------DILKLA-----------QNLAS 209

Query: 225 SSYPPAFPLKHQQKDMRLALAL 246
           S +     +     ++   +A 
Sbjct: 210 SGFRDTSRVGGGNPELGTMMAT 231


>2D0I-A nrPDB
          Length = 333

 Score = 49.3 bits (116), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 5/109 (4%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61
           +VG LG+G +GKA++  L+  G K+  W+R   K +   E  A   +   E+++K    I
Sbjct: 148 KVGILGMGAIGKAIARRLIPFGVKLYYWSRHR-KVNVEKELKARYMD-IDELLEKSDIVI 205

Query: 62  AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITG 110
             L        ++ ++     +  EGK  +++          + EAI  
Sbjct: 206 LALPLTRDTYHIINEER---VKKLEGKYLVNIGRGALVDEKAVTEAIKQ 251


>4DGS-A nrPDB
          Length = 340

 Score = 49.3 bits (116), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 20/109 (18%), Positives = 46/109 (42%), Gaps = 7/109 (6%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61
            +G LGLG +G+A++      G  V  WNR+     + + H     +SP ++ +      
Sbjct: 173 RIGVLGLGQIGRALASRAEAFGMSVRYWNRSTLSGVDWIAH-----QSPVDLARDSDVLA 227

Query: 62  AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITG 110
             ++   A  ++V     +L+ +      ++++  +      + EA+  
Sbjct: 228 VCVAASAATQNIVDA--SLLQALGPEGIVVNVARGNVVDEDALIEALKS 274


>3OJO-A nrPDB
          Length = 431

 Score = 47.4 bits (111), Expect = 8e-06,   Method: Composition-based stats.
 Identities = 52/304 (17%), Positives = 93/304 (30%), Gaps = 43/304 (14%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESP------AEVI- 54
           ++  +GLG +G   S+   K+G  V   +      D+L ++G    E P       EV+ 
Sbjct: 13  KLTVVGLGYIGLPTSIMFAKHGVDVLGVDINQQTIDKL-QNGQISIEEPGLQEVYEEVLS 71

Query: 55  ----------KKCKYTIAMLSDPCAALS--------VVFDKGGVLEQICEGKGYIDMSTV 96
                     +     I  +  P             V+     +L  + +G   I  ST+
Sbjct: 72  SGKLKVSTTPEASDVFIIAVPTPNNDDQYRSCDISLVMRALDSILPFLKKGNTIIVESTI 131

Query: 97  DAETSLKINEAITG-------KGGRFVEGP--VSGSKKPAEDGQLIILAAG-DKALFEES 146
             +T     + +         +    V  P  V   K   E      +  G  KA  E  
Sbjct: 132 APKTMDDFVKPVIENLGFTIGEDIYLVHCPERVLPGKILEELVHNNRIIGGVTKACIEAG 191

Query: 147 IPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMMNAFSEGLVLADKSGLSSDTLLDILD 206
              +    +              KL+ N      +   +E   + +   ++   ++++ +
Sbjct: 192 KRVYRTFVQGEMIETDARTAEMSKLMENTYRDVNIALANELTKICNNLNINVLDVIEMAN 251

Query: 207 LGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDMRLA--LALGDENAVSMP--VAAAANE 262
                N    G G   +  +  P F      KD   A  +  G E   SMP  V     +
Sbjct: 252 KHPRVNIHQPGPGVGGHCLAVDPYF---IIAKDPENAKLIQTGREINNSMPAYVVDTTKQ 308

Query: 263 AFKK 266
             K 
Sbjct: 309 IIKA 312


>4OM8-A nrPDB
          Length = 309

 Score = 47.0 bits (110), Expect = 9e-06,   Method: Composition-based stats.
 Identities = 28/246 (11%), Positives = 69/246 (28%), Gaps = 39/246 (15%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCD------------------ELVEHGA 44
           +  +GLG MG  M+  L + G +V  ++   +  +                   L   G 
Sbjct: 5   IAIIGLGTMGPGMAARLARGGLQVVAYDVAPAAIERARSMLSVAETVLDALGIALPSAGV 64

Query: 45  SVCE---SPAEVIKKCKYTIAMLSDPCAAL-SVVFDKGGVLEQICEGKGYIDMSTVDAET 100
                     + +      I  + +  +    V     G+   I +       ++    T
Sbjct: 65  GTVRFTDDIGDAVSGADLVIENVPENISIKADVYRTIDGL---IGQDTIVASDTSGIPIT 121

Query: 101 SLKINEAITGK--GGRFVEGPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSF 158
            L+ + +   +  G  +   P          G+                     +G    
Sbjct: 122 KLQAHISYPERMVGMHWSNPPHIIPMIEVIAGEKTA-----PQTVATIRDLIRSIGLLPV 176

Query: 159 YLGQVGNGAKMKLIVNMIMGSMMNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGK 218
            + +   G     + N ++ +++    E + L ++  +  + L   +  G        G 
Sbjct: 177 VVKKDVPG----FVENRVLYALLR---EAVDLVERGVIDPEDLDTCVSWGIGYKIAVIGP 229

Query: 219 GPSMNK 224
              ++ 
Sbjct: 230 MALLDM 235


>2WWR-A nrPDB
          Length = 330

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 27/167 (16%), Positives = 60/167 (35%), Gaps = 8/167 (4%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62
           VG +GLG +G+A++  L   G +  ++     + +E  E  A    +P E+  +  + + 
Sbjct: 158 VGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTP-ELAAQSDFIVV 216

Query: 63  MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSG 122
             S   A   +        +++ E   +I++S  D      + +A+           V+ 
Sbjct: 217 ACSLTPATEGLCN--KDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTS 274

Query: 123 SKKPAEDGQLIILAAGD-----KALFEESIPAFDVLGKRSFYLGQVG 164
            +    +  L+ L          +    +     +L   +   G  G
Sbjct: 275 PEPLPTNHPLLTLKNCVILPHIGSATHRTRNTMSLLAANNLLAGLRG 321


>5AOV-A nrPDB
          Length = 336

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 17/108 (15%), Positives = 46/108 (42%), Gaps = 4/108 (3%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62
           +G +G G +G+A++        ++  ++RT  K     E GA       EV+K+  + I 
Sbjct: 153 IGIVGFGRIGQAIARRAKGFNMRILYYSRTR-KSQAEKELGAEY-RPLEEVLKESDFVIL 210

Query: 63  MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITG 110
            +      + ++ ++   L+ +      ++++      +  + +A+  
Sbjct: 211 AVPLTKETMYMINEER--LKLMKPTAILVNIARGKVVDTKALIKALKE 256


>4YPO-A nrPDB
          Length = 333

 Score = 45.9 bits (107), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 23/89 (25%), Positives = 37/89 (41%), Gaps = 3/89 (3%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61
           +VG +G G  G A S++L  +G +V V  +  S+    VE      ++PAEV K     +
Sbjct: 16  KVGVIGYGSQGHAHSLSLRDSGVQVRVGLKQGSRSRPKVEEQGLDVDTPAEVAKWADVVM 75

Query: 62  AMLSDPCAALSVVFDKGGVLEQICEGKGY 90
            +  D   A       G +   +  G   
Sbjct: 76  VLAPDTAQAE---IFAGDIEPNLKPGDAL 101


>1GPJ-A nrPDB
          Length = 404

 Score = 45.5 bits (106), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 20/93 (21%), Positives = 39/93 (41%), Gaps = 4/93 (4%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFK-VTVWNRTLSKCDELVE-HG--ASVCESPAEVIKKCK 58
           V  +G G MGK ++ +L+  G + V V NRT  +  EL    G  A   +   + + +  
Sbjct: 170 VLVVGAGEMGKTVAKSLVDRGVRAVLVANRTYERAVELARDLGGEAVRFDELVDHLARSD 229

Query: 59  YTIAMLSDPCAALSVVFDKGGVLEQICEGKGYI 91
             ++  + P   + V   +  + ++       I
Sbjct: 230 VVVSATAAPHPVIHVDDVREALRKRDRRSPILI 262


>3KBO-A nrPDB
          Length = 315

 Score = 45.1 bits (105), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 23/128 (17%), Positives = 51/128 (39%), Gaps = 15/128 (11%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60
             VG +G G++G  ++ +L   GF +  W+R+  K    VE      E     + + +  
Sbjct: 140 FSVGIMGAGVLGAKVAESLQAWGFPLRCWSRSR-KSWPGVES-YVGREELRAFLNQTRVL 197

Query: 61  IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120
           I +L +    + ++  +  +L+Q+ +G   ++           +   +  +    +    
Sbjct: 198 INLLPNTAQTVGIINSE--LLDQLPDGAYVLN-----------LARGVHVQEADLLAALD 244

Query: 121 SGSKKPAE 128
           SG  K A 
Sbjct: 245 SGKLKGAM 252


>6HD1-C nrPDB
          Length = 459

 Score = 44.3 bits (103), Expect = 5e-05,   Method: Composition-based stats.
 Identities = 34/162 (20%), Positives = 59/162 (36%), Gaps = 19/162 (11%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62
           V   G G  G+++ + +L+ G+ V   +R   K   L+  GA    S +E  KK    I 
Sbjct: 22  VCIFGTGDFGRSLGLKMLQCGYSVVFGSRNPQKTT-LLPSGAE-VLSYSEAAKKSGIIII 79

Query: 63  MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTV-----DAETSLKINEAITGKGGRFVE 117
                 A     +D    L ++  GK  +D+S         E++ +    +   G   V+
Sbjct: 80  ------AIHREHYDFLTELTEVLNGKILVDISNNLKINQYPESNAEYLAHLVP-GAHVVK 132

Query: 118 GP--VSGS--KKPAEDGQLIILAAG-DKALFEESIPAFDVLG 154
               +S    +  A D    +   G D    +  +     LG
Sbjct: 133 AFNTISAWALQSGALDASRQVFVCGNDSKAKQRVMDIVRNLG 174


>4G2N-A nrPDB
          Length = 345

 Score = 44.3 bits (103), Expect = 7e-05,   Method: Composition-based stats.
 Identities = 24/110 (21%), Positives = 46/110 (41%), Gaps = 4/110 (3%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61
            +G  G+G +G+A++      G  +   NRT  +    +E GA   ++   ++      I
Sbjct: 175 RLGIFGMGRIGRAIATRARGFGLAIHYHNRT--RLSHALEEGAIYHDTLDSLLGASD--I 230

Query: 62  AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGK 111
            +++ P       F     + +I EG   I++S  D      + EA+  K
Sbjct: 231 FLIAAPGRPELKGFLDHDRIAKIPEGAVVINISRGDLINDDALIEALRSK 280


>4N18-A nrPDB
          Length = 332

 Score = 43.9 bits (102), Expect = 8e-05,   Method: Composition-based stats.
 Identities = 14/94 (14%), Positives = 36/94 (38%), Gaps = 4/94 (4%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60
             +G +GLG +G  ++  L + G++V+ W+R+  +   +  +           +      
Sbjct: 157 FHIGIMGLGEIGGYIADQLARLGYRVSGWSRSEKQLAGVTCYRGEEALD--HFLGSLDGL 214

Query: 61  IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMS 94
           I +L        ++     +  ++  G   I+  
Sbjct: 215 INLLPLTAQTRGILAAP--LFNRLPAGAVLINCG 246


>3TRI-A nrPDB
          Length = 280

 Score = 43.9 bits (102), Expect = 9e-05,   Method: Composition-based stats.
 Identities = 18/100 (18%), Positives = 36/100 (36%), Gaps = 5/100 (5%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFK---VTVWNRTLSKCDELVEH-GASVCESPAEVIKKCK 58
           + F+G G M + + + L+ NG+    + V NR+L K D   E  G    +   +      
Sbjct: 6   ITFIGGGNMARNIVVGLIANGYDPNRICVTNRSLDKLDFFKEKCGVHTTQDNRQGALNAD 65

Query: 59  YTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDA 98
             +  +  P     V  +   +L +       + +     
Sbjct: 66  VVVLAVK-PHQIKMVCEELKDILSETKILVISLAVGVTTP 104


>5WHX-A nrPDB
          Length = 271

 Score = 43.5 bits (101), Expect = 9e-05,   Method: Composition-based stats.
 Identities = 18/138 (13%), Positives = 51/138 (36%), Gaps = 6/138 (4%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60
           +++G +G G  G+ ++  ++K G  +T  +R+    +  ++ G       +  +      
Sbjct: 10  LKIGIVGFGNFGQFLAKTMIKQGHTLTATSRS-DYSELCLQMGIHFFRDVSAFLTADIDV 68

Query: 61  IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120
           I + +   +   VV      L  +     ++D+ +V  E   ++      +    +    
Sbjct: 69  IVLCTSILSLSEVVGSM--PLTSLKRPTLFVDVLSVK-EHPRELLLRELPEDSDILCTHP 125

Query: 121 SGSKKPAEDG--QLIILA 136
               + A++G      + 
Sbjct: 126 MFGPQTAKNGWTDHTFMY 143


>3GGO-A nrPDB
          Length = 314

 Score = 43.5 bits (101), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 34/206 (16%), Positives = 71/206 (34%), Gaps = 29/206 (14%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGF--KVTVWNRTLSKCDELVEHGAS-VCESPAEVIKKC 57
             V  +G+G MG + + +L ++GF  K+  ++       + V+ G      +    ++  
Sbjct: 34  QNVLIVGVGFMGGSFAKSLRRSGFKGKIYGYDINPESISKAVDLGIIDEGTTSIAKVEDF 93

Query: 58  KYTIAMLSDPCAALSVV---------FDKGGVLEQICEGKGYIDMSTVDAETSLKINEAI 108
                MLS P      +          D     +   +GK   D+  +            
Sbjct: 94  SPDFVMLSSPVRTFREIAKKLSYILSEDATVTDQGSVKGKLVYDLENI------------ 141

Query: 109 TGKGGRFVEG-PVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGA 167
              G RFV G P++G++K   +  L  L  G K +   +        K    + +   G 
Sbjct: 142 --LGKRFVGGHPIAGTEKSGVEYSLDNLYEGKKVILTPTKKTDKKRLKLVKRVWEDVGGV 199

Query: 168 KMKLI--VNMIMGSMMNAFSEGLVLA 191
              +   ++  +  +++     +  A
Sbjct: 200 VEYMSPELHDYVFGVVSHLPHAVAFA 225


>2G5C-A nrPDB
          Length = 281

 Score = 43.5 bits (101), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 34/206 (16%), Positives = 71/206 (34%), Gaps = 29/206 (14%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGF--KVTVWNRTLSKCDELVEHGAS-VCESPAEVIKKC 57
             V  +G+G MG + + +L ++GF  K+  ++       + V+ G      +    ++  
Sbjct: 2   QNVLIVGVGFMGGSFAKSLRRSGFKGKIYGYDINPESISKAVDLGIIDEGTTSIAKVEDF 61

Query: 58  KYTIAMLSDPCAALSVV---------FDKGGVLEQICEGKGYIDMSTVDAETSLKINEAI 108
                MLS P      +          D     +   +GK   D+  +            
Sbjct: 62  SPDFVMLSSPVRTFREIAKKLSYILSEDATVTDQGSVKGKLVYDLENI------------ 109

Query: 109 TGKGGRFVEG-PVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGA 167
              G RFV G P++G++K   +  L  L  G K +   +        K    + +   G 
Sbjct: 110 --LGKRFVGGHPIAGTEKSGVEYSLDNLYEGKKVILTPTKKTDKKRLKLVKRVWEDVGGV 167

Query: 168 KMKLI--VNMIMGSMMNAFSEGLVLA 191
              +   ++  +  +++     +  A
Sbjct: 168 VEYMSPELHDYVFGVVSHLPHAVAFA 193


>4KQW-A nrPDB
          Length = 350

 Score = 43.5 bits (101), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 17/90 (18%), Positives = 33/90 (36%), Gaps = 3/90 (3%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60
           ++VG +G G  G A ++NL+ +G  V V  R  S   +  E             ++    
Sbjct: 28  LKVGIIGYGSQGHAHALNLMDSGVDVRVGLREGSSSWKTAEEAGLKVTDMDTAAEEADVI 87

Query: 61  IAMLSDPCAALSVVFDKGGVLEQICEGKGY 90
           + ++ D      V   +  +   +  G   
Sbjct: 88  MVLVPDEIQ-PKVY--QEHIAAHLKAGNTL 114


>6BII-A nrPDB
          Length = 333

 Score = 42.8 bits (99), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 14/108 (12%), Positives = 43/108 (39%), Gaps = 4/108 (3%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62
           +G +G G +G+A++      G ++    R+  K +   E GA       E++++  + + 
Sbjct: 153 IGIVGFGRIGQAIAKRAKGFGMRILYTARSR-KPEAEKELGAEFKP-LEELLRESDFVVL 210

Query: 63  MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITG 110
            +        ++ ++   L  +      ++++      +  +  A+  
Sbjct: 211 AVPLTKETYHMINEER--LRLMKPTAVLVNVARGKVVDTKALIRALKE 256


>1MV8-A nrPDB
          Length = 436

 Score = 42.4 bits (98), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 34/247 (13%), Positives = 76/247 (30%), Gaps = 44/247 (17%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKC---------------DELVEHGAS 45
           M +   GLG +G   +  L   G +V   + + +K                + L++ G  
Sbjct: 1   MRISIFGLGYVGAVCAGCLSARGHEVIGVDVSSTKIDLINQGKSPIVEPGLEALLQQGRQ 60

Query: 46  VCE-----SPAEVIKKCKYTIAMLSDPCA---------ALSVVFDKGGVLEQICEGKGYI 91
                      + +     +   +  P             +V  + G  + +  E    +
Sbjct: 61  TGRLSGTTDFKKAVLDSDVSFICVGTPSKKNGDLDLGYIETVCREIGFAIREKSERHTVV 120

Query: 92  DMSTVDAET----SLKINEAITGKGGRFVEGPVSGSKKPAED---------GQLIILAAG 138
             STV   T     + + E  +GK    V+  V  + +   +           + ++   
Sbjct: 121 VRSTVLPGTVNNVVIPLIEDCSGKKAG-VDFGVGTNPEFLRESTAIKDYDFPPMTVIGEL 179

Query: 139 DKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMMNAFSEGLVLADKSGLSS 198
           DK   +     +  L         V     +K   N+   + +   +E   +A   G+  
Sbjct: 180 DKQTGDLLEEIYRELDAPIIR-KTVEVAEMIKYTCNVWHAAKVTFANEIGNIAKAVGVDG 238

Query: 199 DTLLDIL 205
             ++D++
Sbjct: 239 REVMDVI 245



 Score = 28.5 bits (62), Expect = 3.0,   Method: Composition-based stats.
 Identities = 22/125 (17%), Positives = 48/125 (38%), Gaps = 19/125 (15%)

Query: 2   EVGFLGLG-IMGKA---------MSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPA 51
           +VG LGL    G           ++  L+  G+++ +++R +        HGA+     +
Sbjct: 315 KVGLLGLSFKAGTDDLRESPLVELAEMLIGKGYELRIFDRNVEYAR---VHGANKEYIES 371

Query: 52  EVIKKCKYTIAMLSDPCAALSVVFDKGG------VLEQICEGKGYIDMSTVDAETSLKIN 105
           ++       ++ L +  A+  V+    G      ++ +   GK  +D+      T+    
Sbjct: 372 KIPHVSSLLVSDLDEVVASSDVLVLGNGDELFVDLVNKTPSGKKLVDLVGFMPHTTTAQA 431

Query: 106 EAITG 110
           E I  
Sbjct: 432 EGICW 436


>5UOG-A nrPDB
          Length = 344

 Score = 42.4 bits (98), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 19/106 (17%), Positives = 35/106 (33%), Gaps = 7/106 (6%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62
           VG  GLG +G A++  L   G  +    RT          G +   +   + +     I 
Sbjct: 167 VGLFGLGRIGLAIARRLEAFGVSIAYHTRTPR-----EGLGFTYHPTLVGMAEAVDTLIV 221

Query: 63  MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAI 108
           ++    + L  V     VL  +      I++          +  A+
Sbjct: 222 IVPGTASTLKAVNA--DVLSALGPKGVLINVGRGSTVDEAALVTAL 265


>3VTF-A nrPDB
          Length = 444

 Score = 42.4 bits (98), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 41/304 (13%), Positives = 95/304 (31%), Gaps = 41/304 (13%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCE-SPAEVIKKC---- 57
           +  LGLG +G   ++     G +V  ++   S  + L      + E    E + +     
Sbjct: 24  LSVLGLGYVGVVHAVGFALLGHRVVGYDVNPSIVERLRAGRPHIYEPGLEEALGRALSSG 83

Query: 58  ---------------KYTIAMLSDPCA---------ALSVVFDKGGVLEQICEGKGYIDM 93
                            T   +  P A           +     G  +         +  
Sbjct: 84  RLSFAESAEEAVAATDATFIAVGTPPAPDGSADLRYVEAAARAVGRGIRAKGRWHLVVVK 143

Query: 94  STVDAETSLKINEAITGKGGRFVEGPVSGSKKPAEDGQL---------IILAAGDKALFE 144
           STV   T+  +      +    V+  V+ + +   +G           I++ AGD+    
Sbjct: 144 STVPPGTTEGLVARAVAEEAGGVKFSVASNPEFLREGSALEDFFKPDRIVIGAGDERAAS 203

Query: 145 ESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMMNAFSEGLVLADKSGLSSDTLLDI 204
             +  +  +      +        +K   N+ +   ++  +E  +LA + G+ +  + + 
Sbjct: 204 FLLDVYKAVDAPKLVMKPR-EAELVKYASNVFLALKISFANEVGLLAKRLGVDTYRVFEA 262

Query: 205 LDLGAMTNPMFKGKGPSMNKSSYP-PAFPLKHQQKDMRLALALGDEN-AVSMPVAAAANE 262
           + L       + G G     S +P          + + L +A+      V+  +   A +
Sbjct: 263 VGLDKRIGRHYFGAGLGFGGSCFPKDTLAFIRFGESLGLEMAISKAVLRVNEYMPRYAVQ 322

Query: 263 AFKK 266
             ++
Sbjct: 323 LLEE 326


>4EBF-A nrPDB
          Length = 334

 Score = 42.4 bits (98), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 26/189 (13%), Positives = 53/189 (28%), Gaps = 21/189 (11%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPA--EVIKKCKYT 60
           VGFLG+G +G AM+  L   G  +       +K  +            A  E+     + 
Sbjct: 149 VGFLGMGAIGLAMADRLQGWGATLQYH---AAKALDTQTEQRLGLRQVACSELFASSDFI 205

Query: 61  IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120
           +  L      L +V  +  +L  +  G   ++           +  A+            
Sbjct: 206 LLALPLNADTLHLVNAE--LLALVRPGALLVNPCRGSVVDEAAVLAALER---------- 253

Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 180
              +       +  +    +A  +        L      L     G+ ++ +   I    
Sbjct: 254 --GQLGGYAADVFEMEDWARA--DRPQQIDPALLAHPNTLFTPHIGSAVRAVRLEIERCA 309

Query: 181 MNAFSEGLV 189
                + L 
Sbjct: 310 AQNILQALA 318


>2I99-A nrPDB
          Length = 312

 Score = 42.4 bits (98), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 22/132 (16%), Positives = 48/132 (36%), Gaps = 18/132 (13%)

Query: 25  KVTVWNRTLSKCDELVE--HG-ASVCESPAEVIKKCKYTIAMLSDPCAALSVVFDKGGVL 81
           +V +WNRT    ++  +   G   VC S  E +      I +     A   ++F      
Sbjct: 162 EVRIWNRTKENAEKFADTVQGEVRVCSSVQEAVAGADVIITV---TLATEPILFG----- 213

Query: 82  EQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSGSKKPAEDGQLIILAAGDKA 141
           E +  G  +I+          ++++ +  +   +V+      ++ A      +L +G   
Sbjct: 214 EWVKPG-AHINAVGASRPDWRELDDELMKEAVLYVDS-----QEAALKESGDVLLSG-AE 266

Query: 142 LFEESIPAFDVL 153
           +F E       +
Sbjct: 267 IFAELGEVIKGV 278


>4TSK-A nrPDB
          Length = 350

 Score = 42.4 bits (98), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 14/99 (14%), Positives = 30/99 (30%), Gaps = 2/99 (2%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61
            +  +G G  G A + NL  +GF V +            E       +  E +++    +
Sbjct: 19  RIAVIGYGSQGHAHAQNLRDSGFDVVI-GLRPGSSWAKAEADGFRVMAVGEAVEESDVIM 77

Query: 62  AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAET 100
            +L D     +V   +        +   +     +    
Sbjct: 78  ILLPDERQ-PAVYEREIRPYLTAGKALAFAHGFNIHFSQ 115


>2HK7-A nrPDB
          Length = 269

 Score = 41.6 bits (96), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 31/117 (26%), Positives = 50/117 (42%), Gaps = 8/117 (6%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGA-SVCESPAEVIKKCKYTI 61
           +  LG G   +A+   L+K G KV +WNRT  K  +L +     V  SP EVI K +  +
Sbjct: 126 ILVLGAGGASRAVIYALVKEGAKVFLWNRTKEKAIKLAQKFPLEVVNSPEEVIDKVQVIV 185

Query: 62  AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEG 118
              S           +    + I +    +D   +  ET  K+ +    KG + ++G
Sbjct: 186 NTTSVGLKDED---PEIFNYDLIKKDHVVVD--IIYKET--KLLKKAKEKGAKLLDG 235


>1NP3-A nrPDB
          Length = 338

 Score = 41.6 bits (96), Expect = 4e-04,   Method: Composition-based stats.
 Identities = 15/65 (23%), Positives = 23/65 (35%)

Query: 2  EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61
          +V  +G G  G A + NL  +G  VTV  R+ S      E            +      +
Sbjct: 18 KVAIIGYGSQGHAHACNLKDSGVDVTVGLRSGSATVAKAEAHGLKVADVKTAVAAADVVM 77

Query: 62 AMLSD 66
           +  D
Sbjct: 78 ILTPD 82


>3MOG-A nrPDB
          Length = 483

 Score = 41.6 bits (96), Expect = 4e-04,   Method: Composition-based stats.
 Identities = 25/189 (13%), Positives = 55/189 (29%), Gaps = 44/189 (23%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVE-----------HGASVCESPA 51
           V  +G G MG  ++     +G +V +++ +       ++            G    E+  
Sbjct: 8   VAVIGSGTMGAGIAEVAASHGHQVLLYDISAEALTRAIDGIHARLNSRVTRGKLTAETCE 67

Query: 52  ------------EVIKKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAE 99
                         +      I   S+       +F +   L ++C  +  +  +   + 
Sbjct: 68  RTLKRLIPVTDIHALAAADLVIEAASERLEVKKALFAQ---LAEVCPPQTLL-TTNTSSI 123

Query: 100 TSLKINEAITG----KGGRFVE-GPVSGSKKPAEDGQLIILAAG---DKALFEESIPAFD 151
           +   I   I       G  F    PV          +L+ + +G      + E+      
Sbjct: 124 SITAIAAEIKNPERVAGLHFFNPAPVM---------KLVEVVSGLATAAEVVEQLCELTL 174

Query: 152 VLGKRSFYL 160
             GK+    
Sbjct: 175 SWGKQPVRC 183


>6C55-A nrPDB
          Length = 340

 Score = 40.8 bits (94), Expect = 6e-04,   Method: Composition-based stats.
 Identities = 14/65 (21%), Positives = 27/65 (41%), Gaps = 1/65 (1%)

Query: 2  EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61
          ++  +G G  G A + NL  NG+ V +      +  +  +         AE +K+    +
Sbjct: 19 KIAVVGYGSQGHAHAQNLKDNGYDVVI-GIRPGRSFDKAKEDGFDVFPVAEAVKQADVIM 77

Query: 62 AMLSD 66
           +L D
Sbjct: 78 VLLPD 82


>2DLD-A nrPDB
          Length = 337

 Score = 40.8 bits (94), Expect = 7e-04,   Method: Composition-based stats.
 Identities = 19/92 (20%), Positives = 41/92 (44%), Gaps = 5/92 (5%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62
           VG +G G +G+     +   G KV  ++   +   EL + G    +S  ++ K+      
Sbjct: 149 VGVVGTGHIGQVFMRIMEGFGAKVIAYDIFKNP--ELEKKGYY-VDSLDDLYKQADVISL 205

Query: 63  MLSDPCAALSVVFDKGGVLEQICEGKGYIDMS 94
            + D  A + ++ DK   + ++ +G   ++ S
Sbjct: 206 HVPDVPANVHMINDKS--IAEMKDGVVIVNCS 235


>4XA8-A nrPDB
          Length = 320

 Score = 40.8 bits (94), Expect = 8e-04,   Method: Composition-based stats.
 Identities = 22/110 (20%), Positives = 45/110 (40%), Gaps = 4/110 (3%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60
           + VG LGLG +G A ++ L ++GF V  W+RT    + +        E+    +   +  
Sbjct: 145 IRVGVLGLGDLGAAAALELARHGFDVRGWSRTPKALEGVSCF--HGLEALPGFLAGSEIV 202

Query: 61  IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITG 110
           + ML        ++  +   L  +  G  +I+++         +  A+  
Sbjct: 203 VVMLPLTPETRGLMNAER--LAHLPRGAKFINVARGPVVDEAALIAALRS 250


>1TXG-A nrPDB
          Length = 335

 Score = 40.5 bits (93), Expect = 8e-04,   Method: Composition-based stats.
 Identities = 30/171 (17%), Positives = 63/171 (36%), Gaps = 21/171 (12%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWN--------RTLSKCDELVEHGASV--CESP 50
           M V  LG G MG A+S+ L+ NG +V +W         +++S   E    G  +   E  
Sbjct: 1   MIVSILGAGAMGSALSVPLVDNGNEVRIWGTEFDTEILKSISAGREHPRLGVKLNGVEIF 60

Query: 51  -AEVIKKCKYTIAMLSDPCAALSVVFDKGGVLEQIC--------EGKGYIDMSTVD-AET 100
             E ++KC     ++    +   V+     +L  +         +G    D S +   E 
Sbjct: 61  WPEQLEKCLENAEVVLLGVSTDGVLPVMSRILPYLKDQYIVLISKGLIDFDNSVLTVPEA 120

Query: 101 SLKINEAITGKGGRFVEGPVSGSKKPAEDGQLIILAAGDKALFEESIPAFD 151
             ++   +  +    + GP    +        ++ ++  ++   +    F+
Sbjct: 121 VWRLKHDLRERTVA-ITGPAIAREVAKRMPTTVVFSSPSESSANKMKEIFE 170


>4WEQ-A nrPDB
          Length = 341

 Score = 40.5 bits (93), Expect = 8e-04,   Method: Composition-based stats.
 Identities = 16/123 (13%), Positives = 44/123 (35%), Gaps = 8/123 (6%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62
           VG +G+G++G+  +  L   GFKV  W+R+    + +  + A+  +     + +  + + 
Sbjct: 164 VGIMGMGVLGQDAARKLAAMGFKVIGWSRSKRVIEGVETYDAAGLD---AFLGRTDFLVG 220

Query: 63  MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSG 122
           +L        +      +  ++     +          + +    +       ++  V G
Sbjct: 221 LLPLTPDTRGIFNAA--LFAKLSRNGPF---GAPVFINAGRGGSQVEADILECLDSGVLG 275

Query: 123 SKK 125
              
Sbjct: 276 GAS 278


>3JTM-A nrPDB
          Length = 351

 Score = 40.5 bits (93), Expect = 9e-04,   Method: Composition-based stats.
 Identities = 17/108 (15%), Positives = 41/108 (37%), Gaps = 2/108 (1%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62
           +G +G G +GK +   L   G  +   +R     +   E GA   E   E++ KC   + 
Sbjct: 167 IGTVGAGRIGKLLLQRLKPFGCNLLYHDRLQMAPELEKETGAKFVEDLNEMLPKCDVIVI 226

Query: 63  MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITG 110
            +        +   +  ++ ++ +G   ++ +         + +A+  
Sbjct: 227 NMPLTEKTRGMFNKE--LIGKLKKGVLIVNNARGAIMERQAVVDAVES 272


>5B37-A nrPDB
          Length = 361

 Score = 40.5 bits (93), Expect = 0.001,   Method: Composition-based stats.
 Identities = 13/53 (24%), Positives = 26/53 (49%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEV 53
           M+V   GLG +GK +  +L ++  ++ V +    K +E+     +    P E+
Sbjct: 170 MKVAVQGLGNVGKNLCRHLHEHDVQLFVSDVDPIKAEEVKRLFGATVVEPTEI 222


>1BG6-A nrPDB
          Length = 359

 Score = 40.1 bits (92), Expect = 0.001,   Method: Composition-based stats.
 Identities = 25/121 (20%), Positives = 41/121 (33%), Gaps = 12/121 (9%)

Query: 4   GFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIAM 63
             LGLG  G A +  L   G  V  W+    +  E+ + GA + E P          +  
Sbjct: 8   AVLGLGNGGHAFAAYLALKGQSVLAWDIDAQRIKEIQDRGAIIAEGPGLAGTAHPDLLTS 67

Query: 64  -----LSDPCAALSVVFD------KGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKG 112
                + D    L VV           +   I EG+  I ++      +L+  + +   G
Sbjct: 68  DIGLAVKDADVILIVVPAIHHASIAANIASYISEGQLII-LNPGATGGALEFRKILRENG 126

Query: 113 G 113
            
Sbjct: 127 A 127


>3DC2-A nrPDB
          Length = 529

 Score = 40.1 bits (92), Expect = 0.001,   Method: Composition-based stats.
 Identities = 31/207 (14%), Positives = 69/207 (33%), Gaps = 23/207 (11%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWN--RTLSKCDELVEHGASVCESPAEVIKKCKYT 60
           VG +GLG +G+ ++  +   G  V  ++   + ++  +L         S  +++ +  + 
Sbjct: 145 VGVVGLGRIGQLVAQRIAAFGAYVVAYDPYVSPARAAQL----GIELLSLDDLLARADFI 200

Query: 61  IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120
              L        ++  +   L +   G   ++ +         + +AITG          
Sbjct: 201 SVHLPKTPETAGLIDKEA--LAKTKPGVIIVNAARGGLVDEAALADAITG---------- 248

Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 180
            G  + A           D  LFE +          S    Q   G  +   V + +   
Sbjct: 249 -GHVRAAGLDVFATEPCTDSPLFELAQVVVTPHLGASTAEAQDRAGTDVAESVRLALAGE 307

Query: 181 MNAFSEGLVLADKSGLSSDTLLDILDL 207
                + + +    G+ ++ +   LDL
Sbjct: 308 F--VPDAVNVGG--GVVNEEVAPWLDL 330


>6G1M-A nrPDB
          Length = 338

 Score = 39.7 bits (91), Expect = 0.001,   Method: Composition-based stats.
 Identities = 20/135 (14%), Positives = 45/135 (33%), Gaps = 13/135 (9%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNG--FKVTVWNRTLSKCD-------ELVEHGASVCESPAE 52
           +VG  G G MG  ++ N+L       V V +      +        L + G  V   P  
Sbjct: 3   KVGIWGFGAMGSGIAKNILSKKNLKLVGVHDFREEYIEKDVGELLGLGKIGIKVYPDPIT 62

Query: 53  VIKKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMS----TVDAETSLKINEAI 108
           ++K+    + +++       V      +L++        +      + D + + +I+   
Sbjct: 63  MVKQTDPDLVVIATNSFISVVKDQIISILKENKNVITIAEEMAFPFSKDPKAANEIDTVA 122

Query: 109 TGKGGRFVEGPVSGS 123
                  +   V+  
Sbjct: 123 KDHNVSVLGTGVNPG 137


>5Z1Z-A nrPDB
          Length = 329

 Score = 39.7 bits (91), Expect = 0.002,   Method: Composition-based stats.
 Identities = 19/117 (16%), Positives = 39/117 (33%), Gaps = 5/117 (4%)

Query: 4   GFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIAM 63
           G +G G +G AM   L   G ++  ++   S     +E G    + P  +  +       
Sbjct: 148 GVIGTGKIGVAMLRILKGFGMRLLAFDPYPSAAA--LELGVEYVDLPT-LFSESDVISLH 204

Query: 64  LSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120
                    ++ +     +Q+  G   ++ S      S    EA+  +    +   V
Sbjct: 205 CPLTPENYHLLNEAA--FDQMKNGVMIVNTSRGALIDSQAAIEALKNQKIGSLGMDV 259


>1YON-A nrPDB
          Length = 303

 Score = 38.9 bits (89), Expect = 0.002,   Method: Composition-based stats.
 Identities = 20/111 (18%), Positives = 36/111 (32%), Gaps = 9/111 (8%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSK--CDELVEH-----GASVCESPAEV 53
           M++  LG G +G+     L K G +V  W R         LVE        S+  +  + 
Sbjct: 1   MKITVLGCGALGQLWLTALCKQGHEVQGWLRVPQPYCSVNLVETDGSIFNESLTANDPDF 60

Query: 54  IKKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYID-MSTVDAETSLK 103
           +      +  L         V      L          + M T++   +++
Sbjct: 61  LATSDLLLVTLKAW-QVSDAVKSLASTLPVTTPILLIHNGMGTIEELQNIQ 110


>5T57-A nrPDB
          Length = 296

 Score = 38.9 bits (89), Expect = 0.003,   Method: Composition-based stats.
 Identities = 30/227 (13%), Positives = 63/227 (27%), Gaps = 33/227 (14%)

Query: 2   EVGFLGLG-IMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60
           ++   G G  MG  ++ NLLK+ ++V+    +      L +     C S    +      
Sbjct: 24  KIALFGAGGKMGVRLAKNLLKSDYRVSHVEVSEVGKKRLKDELGLECVSTEAALDNVDVV 83

Query: 61  IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDA-----ETSLKINEAIT------ 109
           I  + D             +  Q+  G   + +               +   +       
Sbjct: 84  ILAVPDTIIGK----IAAQIAPQLRPGTMVMTLDAAAPFAGHLPDRPDLTYFVAHPCHPL 139

Query: 110 --------GKGGRFVEGPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSF--Y 159
                        +  G        A+      L  G +  F+       V+       Y
Sbjct: 140 IFNDETDPEARRDYFGGG------AAKQSITSALMQGPEEAFDLGEAVAKVIYAPILRSY 193

Query: 160 LGQVGNGAKMKL-IVNMIMGSMMNAFSEGLVLADKSGLSSDTLLDIL 205
              V   A ++  +   I  +++    E +    + G+  +   D L
Sbjct: 194 RLTVDQMALLEPGLSETICATLLQVMREAMDETVRRGVPKEAARDFL 240


>3G79-A nrPDB
          Length = 478

 Score = 38.5 bits (88), Expect = 0.003,   Method: Composition-based stats.
 Identities = 37/246 (15%), Positives = 74/246 (30%), Gaps = 53/246 (21%)

Query: 2   EVGFLGLGIMGKAMS----------------MNLLKNGFKVTVWNR--TLSKCDE----- 38
           ++G LG+G +G   +                 N   +G+K+ + NR  +  K +E     
Sbjct: 20  KIGVLGMGYVGIPAAVLFADAPCFEKVLGFQRNSKSSGYKIEMLNRGESPLKGEEPGLEE 79

Query: 39  ----LVEHGASVCESPAEVIKKCKYTIAMLSDPCAAL--------SVVFDKGGVLEQICE 86
               +V+ G   C      I +       +  P A          +++     V + +  
Sbjct: 80  LIGKVVKAGKFECTPDFSRISELDAVTLAIQTPFANPKDLEPDFSALIDGIRNVGKYLKP 139

Query: 87  GKGYIDMSTVDAETSLKINEAITG------KGGRF--VEGP--VSGSKKPAEDGQLIILA 136
           G   +  ST+   T+  + + I         G  F     P  V   +      +   + 
Sbjct: 140 GMLVVLESTITPGTTEGMAKQILEEESGLKAGEDFALAHAPERVMVGRLLKNIREHDRIV 199

Query: 137 AG-----DKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMMNAFSEGLVLA 191
            G      K   E   P   V   +   +         K   N      + A ++  +  
Sbjct: 200 GGIDEASTKRAVELYSPVLTV--GQVIPMSAT-AAEVTKTAENTFRDLQIAAINQLALYC 256

Query: 192 DKSGLS 197
           +  G++
Sbjct: 257 EAMGIN 262


>5TSD-A nrPDB
          Length = 322

 Score = 38.5 bits (88), Expect = 0.003,   Method: Composition-based stats.
 Identities = 17/68 (25%), Positives = 27/68 (39%), Gaps = 3/68 (4%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62
           VG +GLGI+G+     L   GF V  W+RT    + +    A   +     + K    + 
Sbjct: 145 VGVMGLGILGQDAVAKLKVMGFNVIGWSRTRKTIEGVETFDAGELD---RFLAKTDILVG 201

Query: 63  MLSDPCAA 70
           +L      
Sbjct: 202 LLPLTPET 209


>1GDH-A nrPDB
          Length = 320

 Score = 38.2 bits (87), Expect = 0.004,   Method: Composition-based stats.
 Identities = 15/129 (11%), Positives = 46/129 (35%), Gaps = 2/129 (1%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62
           +G  G G +G+A++         +  ++   +   +   + A+  +S   ++   +    
Sbjct: 149 LGIYGFGSIGQALAKRAQGFDMDIDYFDTHRASSSDEASYQATFHDSLDSLLSVSQ--FF 206

Query: 63  MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSG 122
            L+ P    +  F     ++ + +G   ++ +  D   +  +  A+      +    V  
Sbjct: 207 SLNAPSTPETRYFFNKATIKSLPQGAIVVNTARGDLVDNELVVAALEAGRLAYAGFDVFA 266

Query: 123 SKKPAEDGQ 131
            +    +G 
Sbjct: 267 GEPNINEGY 275


>1ZEJ-A nrPDB
          Length = 293

 Score = 38.2 bits (87), Expect = 0.005,   Method: Composition-based stats.
 Identities = 19/123 (15%), Positives = 40/123 (32%), Gaps = 5/123 (4%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60
           M+V  +G G+MG+ +++ +     +V + + +    +   E       S  E     +  
Sbjct: 13  MKVFVIGAGLMGRGIAIAIASK-HEVVLQDVSEKALEAAREQIPEELLSKIEFTTTLEKV 71

Query: 61  IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITG----KGGRFV 116
                   A    +  K  VL ++         S     +   I E +       G  ++
Sbjct: 72  KDCDIVMEAVFEDLNTKVEVLREVERLTNAPLCSNTSVISVDDIAERLDSPSRFLGVHWM 131

Query: 117 EGP 119
             P
Sbjct: 132 NPP 134


>4A7P-A nrPDB
          Length = 446

 Score = 38.2 bits (87), Expect = 0.005,   Method: Composition-based stats.
 Identities = 41/313 (13%), Positives = 82/313 (26%), Gaps = 52/313 (16%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCD---------------ELVEHGAS 45
           + +  +G G +G          G +V   ++   K +                LV     
Sbjct: 9   VRIAMIGTGYVGLVSGACFSDFGHEVVCVDKDARKIELLHQNVMPIYEPGLDALVASNVK 68

Query: 46  VCE-----SPAEVIKKCKYTIAMLSDP-------CAALSVVFDKGGVLEQICEGKGYIDM 93
                     AE +K        +  P            V      + E + +    +  
Sbjct: 69  AGRLSFTTDLAEGVKDADAVFIAVGTPSRRGDGHADLSYVFAAAREIAENLTKPSVIVTK 128

Query: 94  STVDAETSLKINEAITGKGGRFVEGPVSGSKKPAEDGQLI-------ILAAGDKALF--- 143
           STV   T  ++   I           V  + +   +G  I        +  G +  F   
Sbjct: 129 STVPVGTGDEVERIIAEVAPN-SGAKVVSNPEFLREGAAIEDFKRPDRVVVGTEDEFARQ 187

Query: 144 ---EESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMMNAFSEGLVLADKSGLSSDT 200
              E   P          + G+      +K   N  +   +   +E   L ++ G     
Sbjct: 188 VMREIYRPLSLNQSAPVLFTGRR-TSELIKYAANAFLAVKITFINEIADLCEQVGADVQE 246

Query: 201 LLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDMRLALALGDENAVSMPVAAAA 260
           +   + +       F   G         P +      KD    +    +N   + +  A 
Sbjct: 247 VSRGIGMDNRIGGKFLHAG---------PGYGGSCFPKDTLALMKTAADNETPLRIVEAT 297

Query: 261 NEAFK-KARSLGL 272
            +    + R++G 
Sbjct: 298 VQVNDARKRAMGR 310


>5C5I-A nrPDB
          Length = 316

 Score = 38.2 bits (87), Expect = 0.005,   Method: Composition-based stats.
 Identities = 23/108 (21%), Positives = 46/108 (42%), Gaps = 4/108 (3%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62
           VG LGLG +G A ++ L   GF V  W+R+  +   +  H     E+   ++ + +  + 
Sbjct: 143 VGVLGLGELGAAAALRLRDAGFDVHGWSRSPKEIAGVTCHAGE--ETLERMLGQVEILVC 200

Query: 63  MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITG 110
           +L        ++  +   L  + EG   ++ +      S  + EA+  
Sbjct: 201 LLPLTGETRGLLDARR--LACLPEGAQIVNFARGPILDSAALIEALDS 246


>2AHR-A nrPDB
          Length = 259

 Score = 37.8 bits (86), Expect = 0.005,   Method: Composition-based stats.
 Identities = 33/217 (15%), Positives = 73/217 (33%), Gaps = 21/217 (9%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGAS-VCESPAEVIKKCKY 59
           M++G +G+G M  A+   L +   ++ +   +L +  E+ E  A     S  ++I +   
Sbjct: 4   MKIGIIGVGKMASAIIKGLKQTPHELIISGSSLERSKEIAEQLALPYAMSHQDLIDQVDL 63

Query: 60  TIAMLSDPCAALSVVFDK---GGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFV 116
            I  +         V         +  +  G     ++T   +  L +   +     + +
Sbjct: 64  VILGIK--PQLFETVLKPLHFKQPIISMAAGISLQRLATFVGQD-LPLLRIMPNMNAQIL 120

Query: 117 EGPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMI 176
           +         A  G  ++     + L        D  G  +F + +        L  +  
Sbjct: 121 QS------STALTGNALV----SQELQARVRDLTDSFGS-TFDISEKDFDTFTALAGSSP 169

Query: 177 MGSMMNAFSEGLVLAD-KSGLSSDTLLDILDLGAMTN 212
               +  F E L  A  K+G+     L+I+    + +
Sbjct: 170 AYIYL--FIEALAKAGVKNGIPKAKALEIVTQTVLAS 204


>1J49-A nrPDB
          Length = 333

 Score = 37.8 bits (86), Expect = 0.006,   Method: Composition-based stats.
 Identities = 17/92 (18%), Positives = 41/92 (44%), Gaps = 5/92 (5%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62
           VG +G G +G+     +   G KV  ++   +   EL + G    +S  ++ K+      
Sbjct: 149 VGVVGTGHIGQVFMQIMEGFGAKVITYDIFRNP--ELEKKGYY-VDSLDDLYKQADVISL 205

Query: 63  MLSDPCAALSVVFDKGGVLEQICEGKGYIDMS 94
            + D  A + ++ D+   + ++ +    +++S
Sbjct: 206 HVPDVPANVHMINDES--IAKMKQDVVIVNVS 235


>4ZGS-A nrPDB
          Length = 386

 Score = 37.8 bits (86), Expect = 0.006,   Method: Composition-based stats.
 Identities = 17/108 (15%), Positives = 41/108 (37%), Gaps = 5/108 (4%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62
           VG +G G +G+  +  L   G KV  ++   +    +   G     S  E++        
Sbjct: 181 VGVVGTGAIGQQAARILKGIGCKVFAYDIKPNPA--VEAMGIPYV-SLDELLAMSDIVTL 237

Query: 63  MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITG 110
                 +   ++  +   ++++ +G   I++S      S  + +A+  
Sbjct: 238 HCPLLPSTRQLINKES--IQKMKKGVMLINVSRGGLIDSAALFDALES 283


>4BVA-A nrPDB
          Length = 335

 Score = 37.8 bits (86), Expect = 0.006,   Method: Composition-based stats.
 Identities = 23/139 (16%), Positives = 49/139 (35%), Gaps = 20/139 (14%)

Query: 25  KVTVWNRTLSKCDELVE--HG-ASVCESPAEVIKKCKYTIAMLSDPCAALSVVFDKGGVL 81
           +V +WNRT    ++      G   VC S  E +      I +     A   ++F      
Sbjct: 184 EVRMWNRTRENAEKFASTVQGDVRVCSSVQEAVTGADVIITV---TMATEPILFG----- 235

Query: 82  EQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSGSKKPAEDGQLIILAAGDKA 141
           E +  G  +I+          ++++ +  +   +V+      ++ A      +L +G   
Sbjct: 236 EWVKPG-AHINAVGASRPDWRELDDELMRQAVLYVDS-----REAALKESGDVLLSG-AD 288

Query: 142 LFEESIPAFDVLGKRSFYL 160
           +F E        G +  + 
Sbjct: 289 IFAELGEVIS--GAKPAHC 305


>6HRD-A nrPDB
          Length = 317

 Score = 37.4 bits (85), Expect = 0.007,   Method: Composition-based stats.
 Identities = 15/61 (24%), Positives = 26/61 (42%), Gaps = 5/61 (8%)

Query: 1  MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHG-ASVCESPAEVIKKCKY 59
            VG +G G MG  ++    + G +VTV+       + L+  G   + +S    +   K 
Sbjct: 26 QRVGVVGAGQMGSGIAEVSARAGVEVTVF----EPAEALITAGRNRIVKSLERAVSAGKV 81

Query: 60 T 60
          T
Sbjct: 82 T 82


>5N2I-A nrPDB
          Length = 232

 Score = 37.4 bits (85), Expect = 0.008,   Method: Composition-based stats.
 Identities = 14/110 (12%), Positives = 30/110 (27%), Gaps = 9/110 (8%)

Query: 7   GLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCE----SPAEVIKKCKYTIA 62
           G G  G+ ++      G +V + +R+  +   +               A   +     I 
Sbjct: 27  GTGDQGRGLARRFAMAGHEVILGSRSAERAQAVAAELGEGLPVRGMDNAGAAEAGDVVIV 86

Query: 63  MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKG 112
            +       +++     VL     GK  +D                  +G
Sbjct: 87  AVPWDGH-RALLESLKDVLA----GKIVVDCVNPLGFDKRGAYALPVEEG 131


>4B3J-A nrPDB
          Length = 736

 Score = 37.4 bits (85), Expect = 0.008,   Method: Composition-based stats.
 Identities = 18/89 (20%), Positives = 31/89 (34%), Gaps = 7/89 (7%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKC-------DELVEHGASVCESPAEVI 54
            +G LG G+MG  ++    K G++V + + +L          ++L         +  E  
Sbjct: 343 RIGVLGAGMMGAGIAYVSAKAGYEVVLKDVSLEAAAKGKGYSEKLEAKALERGRTTQERS 402

Query: 55  KKCKYTIAMLSDPCAALSVVFDKGGVLEQ 83
                 I   +D      V F    V E 
Sbjct: 403 DALLARITPTADAADFKGVDFVIEAVFEN 431


>1HL3-A nrPDB
          Length = 358

 Score = 37.0 bits (84), Expect = 0.009,   Method: Composition-based stats.
 Identities = 17/108 (15%), Positives = 41/108 (37%), Gaps = 3/108 (2%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62
           +G +GLG +G+A+++     GF V  ++  LS   E    G     +  +++        
Sbjct: 174 LGIIGLGRVGQAVALRAKAFGFNVLFYDPYLSDGIE-RALGLQRVSTLQDLLFHSD--CV 230

Query: 63  MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITG 110
            L       +        ++Q+ +G   ++ +         + +A+  
Sbjct: 231 TLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQALKE 278


>5E4R-A nrPDB
          Length = 490

 Score = 37.0 bits (84), Expect = 0.010,   Method: Composition-based stats.
 Identities = 37/261 (14%), Positives = 74/261 (28%), Gaps = 47/261 (18%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESP---------AEV 53
           +  LG G  G+A ++NL  +G  V V          L   G S   +           + 
Sbjct: 20  IAILGYGSQGRAWALNLRDSGLNVVV---------GLERQGDSWRRAIDDGFKPMYTKDA 70

Query: 54  IKKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGK--GYIDMSTVDAETSLKINEAITGK 111
           +      + ++ D    +        V + + +G    +     +      KI E     
Sbjct: 71  VAIADIIVFLVPD---MVQKSLWLNSVKDFMKKGADLVFAHGFNIHF----KIIEPPKDS 123

Query: 112 GGRFVEGPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKL 171
              ++  P S         +   +  G             V    + Y    G   +  L
Sbjct: 124 DV-YMIAPKSPGPIVRRSYE---MGGG-------------VPALVAVYQNVSGEALQKAL 166

Query: 172 IVNMIMGSMMNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAF 231
            +   +G       E      K    +D   + + L      + K    ++ +  Y P  
Sbjct: 167 AIAKGIGCARAGVIESTF---KEETETDLFGEQVILVGGIMELIKASFETLVEEGYQPEV 223

Query: 232 PLKHQQKDMRLALALGDENAV 252
                  +++L + L  E  +
Sbjct: 224 AYFETVNELKLIVDLIYEKGL 244


>2QYS-A nrPDB
          Length = 318

 Score = 37.0 bits (84), Expect = 0.010,   Method: Composition-based stats.
 Identities = 23/79 (29%), Positives = 30/79 (37%), Gaps = 11/79 (13%)

Query: 5  FLGLGIMGKAMSMNLLKNGFKVTVWNR-TLSKC---DELVEHGASVC-------ESPAEV 53
          F G G +G  M    LK G    V+ R   SK    DE    GA +        E   E+
Sbjct: 17 FGGTGYIGNHMVKGSLKLGHPTYVFTRPNSSKTTLLDEFQSLGAIIVKGELDEHEKLVEL 76

Query: 54 IKKCKYTIAMLSDPCAALS 72
          +KK    I+ L+ P     
Sbjct: 77 MKKVDVVISALAFPQILDQ 95


>1YQG-A nrPDB
          Length = 263

 Score = 37.0 bits (84), Expect = 0.011,   Method: Composition-based stats.
 Identities = 42/222 (18%), Positives = 79/222 (35%), Gaps = 13/222 (5%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKN-GFKVTVWNRTLSKCDELVEH-GASVCESPAEVIKKCK 58
           M V FLG G M  A++  L+K  G+++ + NR   K + L +  G     +  E+     
Sbjct: 1   MNVYFLGGGNMAAAVAGGLVKQGGYRIYIANRGAEKRERLEKELGVETSATLPELHSDDV 60

Query: 59  YTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEG 118
             +A+      A        G L         +   +     + +I   +    G+ +  
Sbjct: 61  LILAVKPQDMEAACKNIRTNGALVLSVAAGLSVGTLSRYLGGTRRIVRVMPNTPGK-IGL 119

Query: 119 PVSGSKKPAEDGQLIILAAGDKALFEESIPAFDV---LGKRSFYLGQVG-NGAKMKLIVN 174
            VSG    AE  +       D+ + +  + +  +   L       G  G +G+    +  
Sbjct: 120 GVSGMYAEAEVSET------DRRIADRIMKSVGLTVWLDDEEKMHGITGISGSGPAYVFY 173

Query: 175 MIMGSMMNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFK 216
           ++      A  +G  +A+   LS  T    + L   T   F+
Sbjct: 174 LLDALQNAAIRQGFDMAEARALSLATFKGAVALAEQTGEDFE 215


>2CUK-A nrPDB
          Length = 311

 Score = 36.6 bits (83), Expect = 0.013,   Method: Composition-based stats.
 Identities = 18/106 (16%), Positives = 38/106 (35%), Gaps = 9/106 (8%)

Query: 6   LGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIAMLS 65
           +G+G +G+A++   L  G +V    RT      L         S  E++K+         
Sbjct: 150 VGMGRIGQAVAKRALAFGMRVVYHARTP---KPL----PYPFLSLEELLKEADVVSLHTP 202

Query: 66  DPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGK 111
                  ++  +   L  +  G   ++ +      +  + EA+ G 
Sbjct: 203 LTPETHRLLNRER--LFAMKRGAILLNTARGALVDTEALVEALRGH 246


>1ZCJ-A nrPDB
          Length = 463

 Score = 36.6 bits (83), Expect = 0.013,   Method: Composition-based stats.
 Identities = 20/93 (21%), Positives = 36/93 (38%), Gaps = 11/93 (11%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDEL-------VEHGASVCESPAEVIK 55
           VG LGLG MG+ ++++  + G  V        + D         +E  AS      +   
Sbjct: 40  VGVLGLGTMGRGIAISFARVGISVVAVESDPKQLDAAKKIITFTLEKEASRAHQNGQASA 99

Query: 56  KCKYTIAM----LSDPCAALSVVFDKGGVLEQI 84
           K K   +     LS     +  VF+   + +++
Sbjct: 100 KPKLRFSSSTKELSTVDLVVEAVFEDMNLKKKV 132


>3HDH-A nrPDB
          Length = 302

 Score = 36.6 bits (83), Expect = 0.013,   Method: Composition-based stats.
 Identities = 23/95 (24%), Positives = 40/95 (42%), Gaps = 9/95 (9%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRT---LSKCDELVEHGASV------CESPAE 52
            V  +G G+MG  ++      G  V + ++T   L+K  + +E            E+P  
Sbjct: 17  HVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENPKA 76

Query: 53  VIKKCKYTIAMLSDPCAALSVVFDKGGVLEQICEG 87
             +  + T++ +S    A SVV     V+E I E 
Sbjct: 77  GDEFVEKTLSSISTSTDAASVVHSTDLVVEAIVEN 111


>6ABJ-A nrPDB
          Length = 345

 Score = 36.6 bits (83), Expect = 0.013,   Method: Composition-based stats.
 Identities = 12/116 (10%), Positives = 36/116 (31%), Gaps = 5/116 (4%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61
            VG +G G +G+  +  +   G ++  ++   +    +   G         ++ +     
Sbjct: 162 RVGVIGTGQIGETFARIMAGFGCELLAYDPYPNP--RIQALGGRYLA-LDALLAESDIVS 218

Query: 62  AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVE 117
                      ++  +   L  +  G   I+        +  + EA+      ++ 
Sbjct: 219 LHCPLTADTRHLIDAQR--LATMKPGAMLINTGRGALVNAAALIEALKSGQLGYLG 272


>4XDZ-A nrPDB
          Length = 343

 Score = 36.6 bits (83), Expect = 0.014,   Method: Composition-based stats.
 Identities = 35/259 (13%), Positives = 72/259 (27%), Gaps = 43/259 (16%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESP---------AEV 53
           +  LG G  G+A ++NL  +G  V V          L   G S   +           + 
Sbjct: 20  IAILGYGSQGRAWALNLRDSGLNVVV---------GLERQGDSWRRAIDDGFKPMYTKDA 70

Query: 54  IKKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGG 113
           +      + ++ D       +      +++      +     +      KI E       
Sbjct: 71  VAIADIIVFLVPDMVQKSLWLNSVKDFMKK-GADLVFAHGFNIHF----KIIEPPKDSDV 125

Query: 114 RFVEGPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIV 173
            ++  P S         +   +  G             V    + Y    G   +  L +
Sbjct: 126 -YMIAPKSPGPIVRRSYE---MGGG-------------VPALVAVYQNVSGEALQKALAI 168

Query: 174 NMIMGSMMNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPL 233
              +G       E      K    +D   + + L      + K    ++ +  Y P    
Sbjct: 169 AKGIGCARAGVIESTF---KEETETDLFGEQVILVGGIMELIKASFETLVEEGYQPEVAY 225

Query: 234 KHQQKDMRLALALGDENAV 252
                +++L + L  E  +
Sbjct: 226 FETVNELKLIVDLIYEKGL 244


>4N7R-A nrPDB
          Length = 472

 Score = 36.2 bits (82), Expect = 0.015,   Method: Composition-based stats.
 Identities = 16/99 (16%), Positives = 33/99 (33%), Gaps = 9/99 (9%)

Query: 5   FLGLGIMGKAMSMNLLKNGFK-VTVWNRTLSKCDELVEHGASV------CESPAEVIKKC 57
            +G G MGK +  +L+  G   V V NR+  +   + E    +       +       + 
Sbjct: 212 VIGAGKMGKLVIKHLMAKGCTKVVVVNRSEERVSAIREEMPGIEIIYRPLDEMLACASEA 271

Query: 58  KYTIAML--SDPCAALSVVFDKGGVLEQICEGKGYIDMS 94
                      P      V +      ++   + ++D+S
Sbjct: 272 DVVFTSTASETPLFLKEHVENLPQASPEVGGLRHFVDIS 310


>1F14-A nrPDB
          Length = 310

 Score = 36.2 bits (82), Expect = 0.015,   Method: Composition-based stats.
 Identities = 33/241 (13%), Positives = 70/241 (29%), Gaps = 48/241 (19%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRT--------------------------LSK 35
            V  +G G+MG  ++      G  V + ++T                             
Sbjct: 17  HVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENPKA 76

Query: 36  CDELVEHGASVCESPAEVIKKC---KYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYID 92
            DE VE   S   +  +           +  + +     + +F +  + +   E   +  
Sbjct: 77  GDECVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKR--LDKFAAEHTIFAS 134

Query: 93  MSTVDAETSLKIN--EAITGKGGRFVE-GPVSGSKKPAEDGQLIILAAGDKALFEESIPA 149
            ++    TS+           G  F    PV    +  +           +  FE  +  
Sbjct: 135 NTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMT------SQKTFESLVDF 188

Query: 150 FDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMMNAFSEGLVLADKSGLSSDTLLDILDLGA 209
              LGK               ++  +++  +M    E + L ++   S + +   + LGA
Sbjct: 189 SKALGKHPVSCKDTPG----FIVNRLLVPYLM----EAIRLYERGDASKEDIDTAMKLGA 240

Query: 210 M 210
            
Sbjct: 241 G 241


>3ZWA-A nrPDB
          Length = 742

 Score = 36.2 bits (82), Expect = 0.016,   Method: Composition-based stats.
 Identities = 20/93 (21%), Positives = 36/93 (38%), Gaps = 11/93 (11%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDEL-------VEHGASVCESPAEVIK 55
           VG LGLG MG+ ++++  + G  V        + D         +E  AS      +   
Sbjct: 319 VGVLGLGTMGRGIAISFARVGISVVAVESDPKQLDAAKKIITFTLEKEASRAHQNGQASA 378

Query: 56  KCKYTIAM----LSDPCAALSVVFDKGGVLEQI 84
           K K   +     LS     +  VF+   + +++
Sbjct: 379 KPKLRFSSSTKELSTVDLVVEAVFEDMNLKKKV 411


>2VHY-A nrPDB
          Length = 377

 Score = 35.8 bits (81), Expect = 0.020,   Method: Composition-based stats.
 Identities = 17/98 (17%), Positives = 31/98 (31%), Gaps = 8/98 (8%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHG-------ASVCESPAEVI 54
           +V  +G G  G   +      G  VTV +  + K  +L            S        +
Sbjct: 170 DVVVIGAGTAGYNAARIANGMGATVTVLDINIDKLRQLDAEFCGRIHTRYSSAYELEGAV 229

Query: 55  KKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYID 92
           K+    I  +  P A  +       ++  +  G   +D
Sbjct: 230 KRADLVIGAVLVPGA-KAPKLVSNSLVAHMKPGAVLVD 266


>4J90-A nrPDB
          Length = 222

 Score = 35.8 bits (81), Expect = 0.021,   Method: Composition-based stats.
 Identities = 9/59 (15%), Positives = 22/59 (37%), Gaps = 2/59 (3%)

Query: 2  EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60
          +   +GLG  G ++   L + G +V   +    K +    +  +     A   ++ +  
Sbjct: 8  QFAVIGLGRFGGSICKELHRMGHEVLAVDINEEKVNAYASY--ATHAVIANATEENELL 64


>2RCY-A nrPDB
          Length = 262

 Score = 35.5 bits (80), Expect = 0.028,   Method: Composition-based stats.
 Identities = 22/88 (25%), Positives = 36/88 (40%), Gaps = 17/88 (19%)

Query: 1  MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASV-------CESPAEV 53
          +++GF+GLG MG A++  +          N  + K + L  +G S          S  E+
Sbjct: 5  IKLGFMGLGQMGSALAHGIA---------NANIIKKENLFYYGPSKKNTTLNYMSSNEEL 55

Query: 54 IKKCKYTIAMLSDPCAALSVVFDKGGVL 81
           + C   I     P  A SV+ +    L
Sbjct: 56 ARHCD-IIVCAVKPDIAGSVLNNIKPYL 82


>6IUM-B nrPDB
          Length = 701

 Score = 35.5 bits (80), Expect = 0.029,   Method: Composition-based stats.
 Identities = 17/55 (30%), Positives = 24/55 (43%), Gaps = 4/55 (7%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKK 56
           +V  +G G MG  +SMN L  G  VT+    L    E ++ G  +     E   K
Sbjct: 294 KVAVIGAGTMGGGISMNFLNAGIPVTI----LETKQEALDRGVGIIRKNYENSAK 344


>3K96-A nrPDB
          Length = 356

 Score = 35.5 bits (80), Expect = 0.032,   Method: Composition-based stats.
 Identities = 13/43 (30%), Positives = 21/43 (48%)

Query: 2  EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGA 44
           +  LG G  G A+++ L + G KV +W+      DE+   G 
Sbjct: 31 PIAILGAGSWGTALALVLARKGQKVRLWSYESDHVDEMQAEGV 73


>3BA1-A nrPDB
          Length = 333

 Score = 35.1 bits (79), Expect = 0.033,   Method: Composition-based stats.
 Identities = 24/169 (14%), Positives = 50/169 (29%), Gaps = 31/169 (18%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61
            VG +GLG +G A++         ++ ++R+         +G     S  E+       +
Sbjct: 166 RVGIIGLGRIGLAVAERAEAFDCPISYFSRSKKPNTNYTYYG-----SVVELASNSDILV 220

Query: 62  AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121
                      ++  +  V++ +      I++         ++  A+           V 
Sbjct: 221 VACPLTPETTHIINRE--VIDALGPKGVLINIGRGPHVDEPELVSAL-----------VE 267

Query: 122 GSKKPAEDGQLIILAAGDKALFEESIPAFDVLGK--RSFYLGQVGNGAK 168
           G    A              +FE      + L        L  VG+G  
Sbjct: 268 GRLGGAGL-----------DVFEREPEVPEKLFGLENVVLLPHVGSGTV 305


>1CER-O nrPDB
          Length = 331

 Score = 35.1 bits (79), Expect = 0.033,   Method: Composition-based stats.
 Identities = 34/165 (20%), Positives = 55/165 (33%), Gaps = 16/165 (9%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWN-RTLSKC-DELVEHGASVCESPAEVIKKCK 58
           M+VG  G G +G+ +   L   G +V + N  T +K    L+++ +     P EV    +
Sbjct: 1   MKVGINGFGRIGRQVFRILHSRGVEVALINDLTDNKTLAHLLKYDSIYHRFPGEVAYDDQ 60

Query: 59  YTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGR--FV 116
           Y      D  A  +        +     G G +  ST     + K  +A    G +   +
Sbjct: 61  YLYV---DGKAIRATAVKDPKEIPWAEAGVGVVIESTGVFTDADK-AKAHLEGGAKKVII 116

Query: 117 EGP--------VSGSKKPAEDGQLIILAAGDKALFEESIPAFDVL 153
             P        V G    A D     + +          P   VL
Sbjct: 117 TAPAKGEDITIVMGVNHEAYDPSRHHIISNASCTTNSLAPVMKVL 161


>4MIE-A nrPDB
          Length = 351

 Score = 35.1 bits (79), Expect = 0.034,   Method: Composition-based stats.
 Identities = 23/153 (15%), Positives = 51/153 (33%), Gaps = 22/153 (14%)

Query: 1   MEVGFLGLGIMGKAMS---MNLLKNGFKVTVWNRTLSKCDELVE---HGASVCESPAEVI 54
           ++VG +G G MG+A      N+L     V V +      +  V      A V      ++
Sbjct: 15  VKVGVIGTGAMGRAHIDRLTNVLTGAEVVAVTDIDHEAAEAAVRDFHLNAKVYPDDTSLL 74

Query: 55  KKCKY-TIAMLSDPCAALSVV----------FDKGGVLEQICEGKGYIDMSTVDAETSLK 103
           +      + ++S   A  + V          F +  +   +   K  +D     ++  ++
Sbjct: 75  QDPDIDAVFVVSFGGAHEATVLKALDTDKFIFTEKPLATTLEGAKRIVDKELTKSKKVIQ 134

Query: 104 IN-EAITGKGGRF----VEGPVSGSKKPAEDGQ 131
           +       +G R     ++  + G+        
Sbjct: 135 VGFMRRYDQGIRALKEKLDTGIIGAPLVVRASH 167


>2EV9-A nrPDB
          Length = 263

 Score = 35.1 bits (79), Expect = 0.037,   Method: Composition-based stats.
 Identities = 18/69 (26%), Positives = 28/69 (40%), Gaps = 7/69 (10%)

Query: 19  LLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI----AMLSDPCA--ALS 72
           L + G +V VWNRT  +   L E        P E  ++ +  +      L DP A    +
Sbjct: 135 LREAGLEVWVWNRTPQRALALAEEFGLRA-VPLEKAREARLLVNATRVGLEDPSASPLPA 193

Query: 73  VVFDKGGVL 81
            +F + G  
Sbjct: 194 ELFPEEGAA 202


>4DYD-A nrPDB
          Length = 283

 Score = 35.1 bits (79), Expect = 0.039,   Method: Composition-based stats.
 Identities = 34/241 (14%), Positives = 74/241 (30%), Gaps = 52/241 (21%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEH-------------------- 42
           V  LG G++G  ++     +GF VT ++      D   +                     
Sbjct: 7   VTVLGTGVLGSQIAFQTAFHGFAVTAYDINTDALDAAKKRFEGLAAVYEKEVAGAADGAA 66

Query: 43  -----GASVCESPAEVIKKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYI-DMSTV 96
                G    +  A+ +K     I  + +       ++ K G L        +  + ST+
Sbjct: 67  QKALGGIRYSDDLAQAVKDADLVIEAVPESLDLKRDIYTKLGELAPAK--TIFATNSSTL 124

Query: 97  DAET----SLKINEAITGKGGRFV----EGPVSGSKKPAEDGQLIILAAGDKALFEESIP 148
                   + + ++ +       V       V G+ K             D  ++++ + 
Sbjct: 125 LPSDLVGYTGRGDKFLALHFANHVWVNNTAEVMGTTKT------------DPEVYQQVVE 172

Query: 149 AFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMMNAFSEGLVLADKSGLSSDTLLDILDLG 208
               +G     L +   G     ++N ++  +++A +E LV       + D    I    
Sbjct: 173 FASAIGMVPIELKKEKAG----YVLNSLLVPLLDAAAELLVDGIADPETIDKTWRIGTGA 228

Query: 209 A 209
            
Sbjct: 229 P 229


>1QP8-A nrPDB
          Length = 303

 Score = 35.1 bits (79), Expect = 0.041,   Method: Composition-based stats.
 Identities = 18/111 (16%), Positives = 41/111 (36%), Gaps = 10/111 (9%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGA-SVCESPAEVIKKCKYT 60
           +V  LGLG +G  +   L   G +V  ++RT        + G      S  E +++ +  
Sbjct: 126 KVAVLGLGEIGTRVGKILAALGAQVRGFSRTP-------KEGPWRFTNSLEEALREARAA 178

Query: 61  IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGK 111
           +  L        +V  +   L  + E   ++++   +      +   +  +
Sbjct: 179 VCALPLNKHTRGLVKYQH--LALMAEDAVFVNVGRAEVLDRDGVLRILKER 227


>4ZCC-A nrPDB
          Length = 336

 Score = 35.1 bits (79), Expect = 0.042,   Method: Composition-based stats.
 Identities = 7/34 (20%), Positives = 18/34 (52%)

Query: 1  MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLS 34
          + +  +G GI G + +  L   G +V +++++  
Sbjct: 3  VPIAIIGTGIAGLSAAQALTSAGHQVHLFDKSRG 36


>2YQ5-A nrPDB
          Length = 343

 Score = 34.7 bits (78), Expect = 0.052,   Method: Composition-based stats.
 Identities = 18/124 (14%), Positives = 49/124 (39%), Gaps = 13/124 (10%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKC-DELVEHGASVCESPAEVIKKCKY 59
           + VG +G+G +G A++      G KV  ++   +   +  + +          V+K+   
Sbjct: 149 LTVGLIGVGHIGSAVAEIFSAMGAKVIAYDVAYNPEFEPFLTY-----TDFDTVLKEADI 203

Query: 60  TIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAI-----TGKGGR 114
                    +  +++ +K   L+++ +    I+ +  +   +  + +A+      G G  
Sbjct: 204 VSLHTPLFPSTENMIGEKQ--LKEMKKSAYLINCARGELVDTGALIKALQDGEIAGAGLD 261

Query: 115 FVEG 118
            + G
Sbjct: 262 TLAG 265


>2HMT-A nrPDB
          Length = 144

 Score = 34.3 bits (77), Expect = 0.055,   Method: Composition-based stats.
 Identities = 9/59 (15%), Positives = 22/59 (37%), Gaps = 2/59 (3%)

Query: 2  EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60
          +   +GLG  G ++   L + G +V   +    K +    +  +     A   ++ +  
Sbjct: 8  QFAVIGLGRFGGSIVKELHRMGHEVLAVDINEEKVNAYASY--ATHAVIANATEENELL 64


>5BUT-A nrPDB
          Length = 288

 Score = 34.3 bits (77), Expect = 0.059,   Method: Composition-based stats.
 Identities = 9/59 (15%), Positives = 22/59 (37%), Gaps = 2/59 (3%)

Query: 2  EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60
          +   +GLG  G ++   L + G +V   +    K +    +  +     A   ++ +  
Sbjct: 8  QFAVIGLGRFGGSIVKELHRMGHEVLAVDINEEKVNAYASY--ATHAVIANATEENELL 64



 Score = 34.3 bits (77), Expect = 0.059,   Method: Composition-based stats.
 Identities = 9/59 (15%), Positives = 22/59 (37%), Gaps = 2/59 (3%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60
           +   +GLG  G ++   L + G +V   +    K +    +  +     A   ++ +  
Sbjct: 150 QFAVIGLGRFGGSIVKELHRMGHEVLAVDINEEKVNAYASY--ATHAVIANATEENELL 206


>5VJ7-A nrPDB
          Length = 476

 Score = 34.3 bits (77), Expect = 0.064,   Method: Composition-based stats.
 Identities = 19/99 (19%), Positives = 42/99 (42%), Gaps = 2/99 (2%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61
           +V  +G G  G   + +L K G++VT++   L +   ++ +G      P E+++K    +
Sbjct: 156 KVAIIGAGPAGLTCAADLAKMGYEVTIYE-ALHQPGGVLTYGIPEFRLPKEILRKELKKL 214

Query: 62  AMLSDPCAALSVVFDKGGVLEQICEGK-GYIDMSTVDAE 99
           ++L        +V     + E + E    +I       +
Sbjct: 215 SLLGVEIKTDHIVGKTITIQELLQEYDAVFIGTGAGTPK 253


>5YEQ-A nrPDB
          Length = 340

 Score = 34.3 bits (77), Expect = 0.068,   Method: Composition-based stats.
 Identities = 18/66 (27%), Positives = 29/66 (43%), Gaps = 2/66 (3%)

Query: 2  EVGFLGLGIMGKAMSMNLLKNGFKVTV-WNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60
           V  LG G  G+A ++NL  +G KV+V   R  +   +    G     +  E ++     
Sbjct: 19 RVAVLGYGSQGRAWALNLRDSGIKVSVGLEREGNSWKQAENDGFKPLRT-EEAVRNSDII 77

Query: 61 IAMLSD 66
          I +L D
Sbjct: 78 IFLLPD 83


>6IH4-A nrPDB
          Length = 338

 Score = 34.3 bits (77), Expect = 0.069,   Method: Composition-based stats.
 Identities = 20/112 (17%), Positives = 41/112 (36%), Gaps = 11/112 (9%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCE----SPAEVIKKCK 58
           +G  G+G +G+A++  L   GF++   N        L             +  E+++KC 
Sbjct: 148 LGIRGMGAVGRAIAQRL--AGFEM---NLLYCDEIPLNAEQEKAWHVQRVTLDELLEKCD 202

Query: 59  YTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITG 110
           Y + M+      L ++      L ++  G   I+           +  A+  
Sbjct: 203 YVVPMVPMAAETLHLIDATA--LAKMKTGSYLINACRGSVVDENAVIAALAS 252


>3KB6-A nrPDB
          Length = 334

 Score = 33.9 bits (76), Expect = 0.092,   Method: Composition-based stats.
 Identities = 20/107 (18%), Positives = 45/107 (42%), Gaps = 5/107 (4%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60
           + +G +G G +G  ++M  L  G KV  ++    K ++L E G  V  S  E++K+    
Sbjct: 142 LTLGVIGTGRIGSRVAMYGLAFGMKVLCYDVV--KREDLKEKGC-VYTSLDELLKESDVI 198

Query: 61  IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEA 107
              +        ++ ++   +  + +G   I+ +      +  +  A
Sbjct: 199 SLHVPYTKETHHMINEER--ISLMKDGVYLINTARGKVVDTDALYRA 243


>3I83-A nrPDB
          Length = 320

 Score = 33.9 bits (76), Expect = 0.093,   Method: Composition-based stats.
 Identities = 44/305 (14%), Positives = 89/305 (29%), Gaps = 48/305 (15%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHG---------------AS 45
           + +  +G G +G      L K G  V+V   + S  + +   G               A+
Sbjct: 3   LNILVIGTGAIGSFYGALLAKTGHCVSV--VSRSDYETVKAKGIRIRSATLGDYTFRPAA 60

Query: 46  VCESPAEVIKKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYI-DMSTVDAETSLKI 104
           V  S AE+  K   T+  +     A  V   +  V      G   I +   ++ E +   
Sbjct: 61  VVRSAAELETKPDCTLLCIKVVEGADRVGLLRDAVAP--DTGIVLISNGIDIEPEVAAAF 118

Query: 105 NEAITGKGGRFVEGPVSGSKKPAEDGQLIIL----AAGDKALFEESIPAFDVLG------ 154
            +     G  F+    +   +        ++      G     +    AF+  G      
Sbjct: 119 PDNEVISGLAFIGVTRTAPGEIWHQAYGRLMLGNYPGGVSERVKTLAAAFEEAGIDGIAT 178

Query: 155 -----KRSFYLGQVGNGAKMKLIVNMIMGSMMNAFSEGL---------VLADKSGLSSDT 200
                 R            + ++   +    + +  EG           +A  +G     
Sbjct: 179 ENITTARWQKCVWNAAFNPLSVLSGGLDTLDILSTQEGFVRAIMQEIRAVAAANGHPLPE 238

Query: 201 LLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDMRLALALGDENAVSMPVAAAA 260
             DI++    +         SM    +    P++ +   +  A+  G    V++P   + 
Sbjct: 239 --DIVEKNVASTYKMPPYKTSMLV-DFEAGQPMETEVI-LGNAVRAGRRTRVAIPHLESV 294

Query: 261 NEAFK 265
               K
Sbjct: 295 YALMK 299


>6ACQ-A nrPDB
          Length = 302

 Score = 33.5 bits (75), Expect = 0.097,   Method: Composition-based stats.
 Identities = 36/234 (15%), Positives = 68/234 (29%), Gaps = 42/234 (17%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDE-----------LVEHGASVCESP 50
           +V  +G G MG  ++      GF+V + +      D            LV+ G     + 
Sbjct: 23  KVCVIGAGTMGSGIAQAFAAKGFEVVLRDIKDEFVDRGLDFINKNLSKLVKKGKIEEATK 82

Query: 51  AEV------------IKKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDA 98
            E+               C   I    +       +F    +             ++  +
Sbjct: 83  VEILTRISGTVDLNMAADCDLVIEAAVERMDIKKQIFA--DLDNICKPETILASNTSSLS 140

Query: 99  ETSLKINEAITGK--GGRFVE-GPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGK 155
            T +        K  G  F    PV    +    G         +  F+        +GK
Sbjct: 141 ITEVASATKRPDKVIGMHFFNPAPVMKLVEVIR-GIAT-----SQETFDAVKETSIAIGK 194

Query: 156 RSFYLGQVGNGAKMKLIVNMIMGSMMNAFSEGLVLADKSGLSSDTLLDILDLGA 209
               + +         +VN I+  M+N   E + +  +   S + +   + LGA
Sbjct: 195 DPVEVAEAPG-----FVVNRILIPMIN---EAVGILAEGIASVEDIDKAMKLGA 240


>2RIR-A nrPDB
          Length = 300

 Score = 33.5 bits (75), Expect = 0.099,   Method: Composition-based stats.
 Identities = 23/131 (17%), Positives = 41/131 (31%), Gaps = 15/131 (11%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVC--ESPAEVIKKCKY 59
           +V  LGLG  G  ++      G  V V  R+ +    + E G      +   E +K    
Sbjct: 159 QVAVLGLGRTGMTIARTFAALGANVKVGARSSAHLARITEMGLVPFHTDELKEHVKDIDI 218

Query: 60  TIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGP 119
            I  +         +     VL  +      +D+++    T  K  E    +G + +  P
Sbjct: 219 CINTIPS-------MILNQTVLSSMTPKTLILDLASRPGGTDFKYAE---KQGIKALLAP 268

Query: 120 VSGSKKPAEDG 130
                      
Sbjct: 269 ---GLPGIVAP 276


>3KKJ-A nrPDB
          Length = 336

 Score = 33.5 bits (75), Expect = 0.11,   Method: Composition-based stats.
 Identities = 7/34 (20%), Positives = 18/34 (52%)

Query: 1  MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLS 34
          + +  +G GI G + +  L   G +V +++++  
Sbjct: 3  VPIAIIGTGIAGLSAAQALTAAGHQVHLFDKSRG 36


>5JFC-L nrPDB
          Length = 474

 Score = 33.5 bits (75), Expect = 0.12,   Method: Composition-based stats.
 Identities = 15/55 (27%), Positives = 27/55 (49%), Gaps = 1/55 (1%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKK 56
           +V  +G G  G   + +L K G++VT++         L+ +G      P E++KK
Sbjct: 156 KVAIIGAGPAGLTCAADLAKMGYEVTIYEALHQPGGVLI-YGIPEFRLPKEIVKK 209


>4LSW-A nrPDB
          Length = 318

 Score = 33.1 bits (74), Expect = 0.13,   Method: Composition-based stats.
 Identities = 16/107 (14%), Positives = 35/107 (32%), Gaps = 6/107 (5%)

Query: 4   GFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIAM 63
           G LGLG +G  ++  L     +++  +              +  E    + +   +    
Sbjct: 149 GVLGLGRIGFEVARRLAGFDMQISYSDIAPKSYAP----DWTFVEDAVTLARDVDFLFVT 204

Query: 64  LSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITG 110
           L+   A   +V     V+E +      I++S         +  A+  
Sbjct: 205 LAASAATRHIVG--RDVIEALGPEGMLINISRASNIDEEALIAALAD 249


>4A5O-A nrPDB
          Length = 286

 Score = 33.1 bits (74), Expect = 0.14,   Method: Composition-based stats.
 Identities = 23/130 (17%), Positives = 41/130 (31%), Gaps = 28/130 (21%)

Query: 1   MEVGFLGLGIM-GKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKY 59
           M+   +G   + G+ M++ LL  G  VTV +R                   A+ + +   
Sbjct: 162 MDAVVVGASNIVGRPMALELLLGGCTVTVTHRFT--------------RDLADHVSRADL 207

Query: 60  TIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINE---AITGKGGRFV 116
            +     P              E I EG   ID+          + +    +  +   ++
Sbjct: 208 VVVAAGKPGLVKG---------EWIKEGAIVIDVGINRQADGRLVGDVEYEVAAQRASWI 258

Query: 117 EGPVSGSKKP 126
             PV G   P
Sbjct: 259 -TPVPGGVGP 267


>3TWO-A nrPDB
          Length = 348

 Score = 33.1 bits (74), Expect = 0.15,   Method: Composition-based stats.
 Identities = 13/67 (19%), Positives = 28/67 (41%), Gaps = 1/67 (1%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCES-PAEVIKKCKYT 60
           +VG  G G +G       +  G +V+V+ R   K  + +  G     + P +  ++  + 
Sbjct: 179 KVGVAGFGGLGSMAVKYAVAMGAEVSVFARNEHKKQDALSMGVKHFYTDPKQCKEELDFI 238

Query: 61  IAMLSDP 67
           I+ +   
Sbjct: 239 ISTIPTH 245


>3FR8-A nrPDB
          Length = 525

 Score = 32.8 bits (73), Expect = 0.18,   Method: Composition-based stats.
 Identities = 14/101 (13%), Positives = 33/101 (32%), Gaps = 17/101 (16%)

Query: 2   EVGFLGLGIMGKAMSMNL------------LKNGFKVTVWNRTLSKCDELVEHGASVCES 49
           ++G +G G  G A + NL            +K G +    +   ++     E   ++ + 
Sbjct: 56  QIGVIGWGSQGPAQAQNLRDSLAEAKSDIVVKIGLRKGSKSFDEARAAGFTEESGTLGD- 114

Query: 50  PAEVIKKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGY 90
             E +      + ++SD   A     +   +   +      
Sbjct: 115 IWETVSGSDLVLLLISDAAQAD----NYEKIFSHMKPNSIL 151


>4A6N-B nrPDB
          Length = 398

 Score = 32.8 bits (73), Expect = 0.21,   Method: Composition-based stats.
 Identities = 11/35 (31%), Positives = 18/35 (51%)

Query: 3  VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCD 37
          V  +G G +G  M+  L +NG  V+V+ R   +  
Sbjct: 29 VAIIGGGPVGLTMAKLLQQNGIDVSVYERDNDREA 63


>1JAY-A nrPDB
          Length = 212

 Score = 32.8 bits (73), Expect = 0.21,   Method: Composition-based stats.
 Identities = 17/99 (17%), Positives = 32/99 (32%), Gaps = 13/99 (13%)

Query: 1  MEVGFLG-LGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESP-------AE 52
          M V  LG  G +GK +++ L   G ++ V +R   K +        +            +
Sbjct: 1  MRVALLGGTGNLGKGLALRLATLGHEIVVGSRREEKAEAKAAEYRRIAGDASITGMKNED 60

Query: 53 VIKKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYI 91
            + C   +  +           D    L+ I   K  +
Sbjct: 61 AAEACDIAVLTIP-----WEHAIDTARDLKNILREKIVV 94


>2OME-A nrPDB
          Length = 336

 Score = 32.4 bits (72), Expect = 0.22,   Method: Composition-based stats.
 Identities = 15/108 (13%), Positives = 39/108 (36%), Gaps = 3/108 (2%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62
           +G +G G  G+A+++     GF V  ++  L    E    G     +  +++ +      
Sbjct: 155 LGLIGFGRTGQAVAVRAKAFGFSVIFYDPYLQDGIE-RSLGVQRVYTLQDLLYQSD--CV 211

Query: 63  MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITG 110
            L       +        ++Q+ +G   ++ +         + +A+  
Sbjct: 212 SLHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVDEKALAQALKE 259


>6NRP-A nrPDB
          Length = 263

 Score = 32.0 bits (71), Expect = 0.31,   Method: Composition-based stats.
 Identities = 13/31 (41%), Positives = 17/31 (54%)

Query: 12 GKAMSMNLLKNGFKVTVWNRTLSKCDELVEH 42
          GKA+++ L K GF VTV  R+     E V  
Sbjct: 37 GKAIALQLAKAGFDVTVHARSRQAEAEQVVQ 67


>3LK7-A nrPDB
          Length = 451

 Score = 31.6 bits (70), Expect = 0.36,   Method: Composition-based stats.
 Identities = 32/159 (20%), Positives = 55/159 (34%), Gaps = 28/159 (17%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTV-----WNRTLSKCDELVEHGASVC--ESPAEVI 54
           +V  LGL   G+A +  L K G  VTV     ++   +    L+E G  V     P E++
Sbjct: 11  KVLVLGLARSGEAAARLLAKLGAIVTVNDGKPFDENPT-AQSLLEEGIKVVCGSHPLELL 69

Query: 55  KKCKYTIAMLSDP------CAALSVVFDKGGVLEQICEGKGY-------IDMSTVDAETS 101
            +      M+ +P            +  +  VL ++             I  S     T+
Sbjct: 70  DED--FCYMIKNPGIPYNNPMVKKALEKQIPVLTEVELAYLVSESQLIGITGSNGKTTTT 127

Query: 102 LKINEAITGKG-----GRFVEGPVSGSKKPAEDGQLIIL 135
             I E +   G        +  P S   + A D   +++
Sbjct: 128 TMIAEVLNAGGQRGLLAGNIGFPASEVVQAANDKDTLVM 166


>5OES-A nrPDB
          Length = 483

 Score = 31.6 bits (70), Expect = 0.37,   Method: Composition-based stats.
 Identities = 18/89 (20%), Positives = 36/89 (40%), Gaps = 4/89 (4%)

Query: 12  GKAMSMNLLKNGFKVTVWNRTLS-KCDELVEHG-ASVCESPAEVIKKCKYTIAMLSDPCA 69
           G+A+++   + G+  + +N     K   L+E   A  C S +  +   K     L+ P  
Sbjct: 270 GQAVAVIYFRAGYAPSDYNSESEWKARLLMEQSRAVKCPSISYHLAGSKKIQQELAKPNV 329

Query: 70  ALSVVFDKGGV--LEQICEGKGYIDMSTV 96
               + +K  +  L +   G   +D S +
Sbjct: 330 LERFLENKDDIAKLRKCFAGLWSLDESDI 358


>2EGG-A nrPDB
          Length = 297

 Score = 31.6 bits (70), Expect = 0.38,   Method: Composition-based stats.
 Identities = 16/91 (17%), Positives = 28/91 (30%), Gaps = 10/91 (10%)

Query: 30  NRTLSKCDELVEHG------ASVCESPAEVIKKCKYTIAMLSDPCAALSVVFDKGGVLEQ 83
           NRT+ K + LV  G                + +    I   S        V      LE+
Sbjct: 172 NRTVEKAERLVREGDERRSAYFSLAEAETRLAEYDIIINTTSVGMHPRVEVQPLS--LER 229

Query: 84  ICEGKGYIDMSTVDAETSLKINEAITGKGGR 114
           +  G    D+   +   +  + +    +G R
Sbjct: 230 LRPGVIVSDIIY-NPLETKWL-KEAKARGAR 258


>4KUG-A nrPDB
          Length = 290

 Score = 31.6 bits (70), Expect = 0.39,   Method: Composition-based stats.
 Identities = 17/60 (28%), Positives = 30/60 (50%), Gaps = 5/60 (8%)

Query: 2  EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHG-ASVCESPAEVIKKCKYT 60
          +V  LG G MG  +       G +V V +      +E V+ G A++ +S ++++ K K T
Sbjct: 3  KVFVLGAGTMGAGIVQAFAAKGCEVIVRDIK----EEFVDRGIATITKSLSKLVAKEKIT 58


>4CUK-A nrPDB
          Length = 338

 Score = 31.6 bits (70), Expect = 0.42,   Method: Composition-based stats.
 Identities = 17/117 (14%), Positives = 36/117 (30%), Gaps = 5/117 (4%)

Query: 4   GFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIAM 63
           G +G G +G A    L   G ++  ++   S     ++ G    +    +  +       
Sbjct: 148 GVIGTGKIGVAALRILKGFGMRLLAFDPYPSTAA--LDLGVEYVD-LQTLFAESDVISLH 204

Query: 64  LSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120
                    ++       +Q+  G   I+ S      S    EA+  +    +   V
Sbjct: 205 CPLTPENYHLLN--HAAFDQMKNGVMIINTSRGALIDSQAAIEALKNQKIGSLGMDV 259


>1GEG-A nrPDB
          Length = 256

 Score = 31.6 bits (70), Expect = 0.44,   Method: Composition-based stats.
 Identities = 17/94 (18%), Positives = 33/94 (35%), Gaps = 14/94 (14%)

Query: 12  GKAMSMNLLKNGFKVTV--WNRTLSKCDELVEHGASVCESPAEVIKKCKYTIAMLSDPCA 69
           GKA+++ L+K+GF V +  +N   +K          V     +           +SD   
Sbjct: 15  GKAIALRLVKDGFAVAIADYNDATAKA---------VASEINQAGGHAVAVKVDVSDRDQ 65

Query: 70  ALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLK 103
             + V      L         ++ + V   T ++
Sbjct: 66  VFAAVEQARKTLGGF---DVIVNNAGVAPSTPIE 96


>1A5Z-A nrPDB
          Length = 319

 Score = 31.6 bits (70), Expect = 0.45,   Method: Composition-based stats.
 Identities = 10/24 (41%), Positives = 16/24 (66%)

Query: 1  MEVGFLGLGIMGKAMSMNLLKNGF 24
          M++G +GLG +G + +  LL  GF
Sbjct: 1  MKIGIVGLGRVGSSTAFALLMKGF 24


>5Y77-A nrPDB
          Length = 473

 Score = 31.2 bits (69), Expect = 0.50,   Method: Composition-based stats.
 Identities = 17/119 (14%), Positives = 40/119 (33%), Gaps = 7/119 (5%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHG----ASVCESPAEVIKKC 57
           +V  +G G+ G  ++  L +NG++V ++ R      E    G     ++ E  A  ++  
Sbjct: 10  QVTIIGAGLAGTLVARLLARNGWQVNLFERRPDPRIETGARGRSINLALAERGAHALRLA 69

Query: 58  KYTIAMLSDPCAALSVVFDKGGVLEQICE---GKGYIDMSTVDAETSLKINEAITGKGG 113
                +L++       +    G    +         +  S      +  + +     G 
Sbjct: 70  GLEREVLAEAVMMRGRMVHVPGTPPNLQPYGRDDSEVIWSINRDRLNRILLDGAEAAGA 128


>4PRK-A nrPDB
          Length = 336

 Score = 31.2 bits (69), Expect = 0.50,   Method: Composition-based stats.
 Identities = 14/109 (12%), Positives = 37/109 (33%), Gaps = 6/109 (5%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62
           +G +G+G +G A++      G KV  ++   +                  V+K+      
Sbjct: 149 IGLIGVGHIGSAVAQIFSAMGAKVLAYDVIYNP----EVEPYLTYADFDTVLKEADIISL 204

Query: 63  MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGK 111
                 +  +++  K     ++      I+ +  +   +  + EA+   
Sbjct: 205 HTPLLKSTENMIGKKQ--FAEMKNDAILINAARGELVDTAALIEALEKH 251


>3WNV-A nrPDB
          Length = 330

 Score = 31.2 bits (69), Expect = 0.51,   Method: Composition-based stats.
 Identities = 19/118 (16%), Positives = 41/118 (34%), Gaps = 5/118 (4%)

Query: 16  SMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIAMLSDPCAALSVVF 75
           +      G  +   NR  +K    +E GA    S  E++ +       L+   +   ++ 
Sbjct: 170 ARRARAFGMNIIYHNR--NKLPPELEDGAKYV-SFDELLAQSDVFSLNLALNASTRHIIG 226

Query: 76  DKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSGSKKPAEDGQLI 133
           +K   L ++ +G   ++ +         +  A+       V   V  ++   E G L 
Sbjct: 227 EKE--LAKMKDGVVIVNTARGALIDEKALVRALESGKVASVGLDVYENEPQVEPGLLN 282


>2EW2-A nrPDB
          Length = 316

 Score = 31.2 bits (69), Expect = 0.52,   Method: Composition-based stats.
 Identities = 44/306 (14%), Positives = 90/306 (29%), Gaps = 41/306 (13%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKY- 59
           M++   G G MG  + + L + G  VT+ ++  +  + + ++G     +  EV+      
Sbjct: 4   MKIAIAGAGAMGSRLGIMLHQGGNDVTLIDQWPAHIEAIRKNGLIADFNGEEVVANLPIF 63

Query: 60  -------------TIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINE 106
                         I  L+      ++      ++ +       ++    +      + +
Sbjct: 64  SPEEIDHQNEQVDLIIALTKAQQLDAMFKAIQPMITEKTYVLCLLNGLGHEDVLEKYVPK 123

Query: 107 AITGKGGRFVEGPVSGS--KKPAEDGQL---IILAAGDKALFEESIPAFDVLGKRSFYLG 161
                G       + G    K   DG++    I  +G K   E  +  F   G    Y  
Sbjct: 124 ENILVGITMWTAGLEGPGRVKLLGDGEIELENIDPSGKKFALE-VVDVFQKAGLNPSYSS 182

Query: 162 QVGNGAKMKLIVNM-------IMGSMMNAFS-----EGL--VLADKSGLSSDTLLDILDL 207
            V      K  VN        I+   +  F      E L   L  +    ++     LD 
Sbjct: 183 NVRYSIWRKACVNGTLNGLCTILDCNIAEFGALPVSESLVKTLISEFAAVAEKEAIYLDQ 242

Query: 208 GAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDM-------RLALALGDENAVSMPVAAAA 260
             +   + +   P+     YP  +    +   +             G +  V+ P  A  
Sbjct: 243 AEVYTHIVQTYDPNGIGLHYPSMYQDLIKNHRLTEIDYINGAVWRKGQKYNVATPFCAML 302

Query: 261 NEAFKK 266
            +    
Sbjct: 303 TQLVHG 308


>1NYT-A nrPDB
          Length = 271

 Score = 31.2 bits (69), Expect = 0.52,   Method: Composition-based stats.
 Identities = 13/48 (27%), Positives = 24/48 (50%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCE 48
           + +  +G G   + + + LL     VT+ NRT+S+ +EL +  A    
Sbjct: 120 LRILLIGAGGASRGVLLPLLSLDCAVTITNRTVSRAEELAKLFAHTGS 167


>6C6P-A nrPDB
          Length = 458

 Score = 31.2 bits (69), Expect = 0.55,   Method: Composition-based stats.
 Identities = 16/41 (39%), Positives = 25/41 (60%)

Query: 2  EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEH 42
          EV  +G G++G A++  L ++G KVTV  R L + D +V  
Sbjct: 9  EVIIVGAGVLGSALAAVLSRDGRKVTVIERDLKEPDRIVGE 49


>4FQ8-A nrPDB
          Length = 271

 Score = 31.2 bits (69), Expect = 0.57,   Method: Composition-based stats.
 Identities = 23/106 (21%), Positives = 39/106 (36%), Gaps = 5/106 (4%)

Query: 5   FLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIAML 64
            LG G   KA++  L K G +V+V NR+    D     G      P +        I   
Sbjct: 123 ILGAGGSAKALACELKKQGLQVSVLNRSSRGLDFFQRLGCDCFMEPPK--SAFDLIIN-- 178

Query: 65  SDPCAALSVVFDKGGVLEQ-ICEGKGYIDMSTVDAETSLKINEAIT 109
           +   +  + +     VL+    EGK   D++       L + + + 
Sbjct: 179 ATSASLHNELPLNKEVLKGYFKEGKLAYDLAAGFLTPFLSLAKELK 224


>3QY9-A nrPDB
          Length = 243

 Score = 30.8 bits (68), Expect = 0.62,   Method: Composition-based stats.
 Identities = 14/121 (11%), Positives = 36/121 (29%), Gaps = 13/121 (10%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFK-VTVWNRTLSKCDELVEHG----ASVCESPAEVIK 55
           M++  +G G M + ++    + G + V V   T        ++         +   +   
Sbjct: 4   MKILLIGYGAMNQRVARLAEEKGHEIVGVIENTPKATTPYQQYQHIADVKGADVAIDFSN 63

Query: 56  KC--------KYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEA 107
                      + + ++         + +K   L Q        +MS      +  +  A
Sbjct: 64  PNLLFPLLDEDFHLPLVVATTGEKEKLLNKLDELSQNMPVFFSANMSYGVHALTKILAAA 123

Query: 108 I 108
           +
Sbjct: 124 V 124


>4K28-A nrPDB
          Length = 269

 Score = 30.8 bits (68), Expect = 0.66,   Method: Composition-based stats.
 Identities = 18/129 (13%), Positives = 43/129 (33%), Gaps = 13/129 (10%)

Query: 5   FLGLGIMGKAMSMNLLKNGF-KVTVWNRTLSKCD---ELVEHG--ASVCESPAEVIKKCK 58
            +G G +G A++  L + G   +T+ + + ++     EL+ +G       +    ++   
Sbjct: 130 VIGCGGVGSAIAYALAEAGIASITLCDPSTARMGAVCELLGNGFPGLTVSTQFSGLEDFD 189

Query: 59  YTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEG 118
                        + +     +L  +       D+ T   E +  +N        R V  
Sbjct: 190 LVANASPVGMGTRAELPLSAALLATLQPDTLVADVVT-SPEITPLLNR------ARQVGC 242

Query: 119 PVSGSKKPA 127
            +    + A
Sbjct: 243 RIQTGPEMA 251


>4HY3-A nrPDB
          Length = 365

 Score = 30.8 bits (68), Expect = 0.67,   Method: Composition-based stats.
 Identities = 19/109 (17%), Positives = 43/109 (39%), Gaps = 4/109 (3%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61
           E+G +G G +GKA+   L     ++ V++  L +   ++E       S  +V+ K  +  
Sbjct: 178 EIGIVGFGDLGKALRRVLSGFRARIRVFDPWLPRS--MLEENGVEPASLEDVLTKSDFIF 235

Query: 62  AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITG 110
            + +        +  +      +  G  +I +S  D      +  A++ 
Sbjct: 236 VVAAVTSENKRFLGAEA--FSSMRRGAAFILLSRADVVDFDALMAAVSS 282


>3GT0-A nrPDB
          Length = 247

 Score = 30.8 bits (68), Expect = 0.67,   Method: Composition-based stats.
 Identities = 15/69 (21%), Positives = 28/69 (40%), Gaps = 5/69 (7%)

Query: 2  EVGFLGLGIMGKAMS-----MNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKK 56
          ++GF+G G MG AM       N++ +   +     T +  +   ++G +      EV K 
Sbjct: 4  QIGFIGCGNMGMAMIGGMINKNIVSSNQIICSDLNTANLKNASEKYGLTTTTDNNEVAKN 63

Query: 57 CKYTIAMLS 65
              I  + 
Sbjct: 64 ADILILSIK 72


>4FSH-A nrPDB
          Length = 271

 Score = 30.8 bits (68), Expect = 0.68,   Method: Composition-based stats.
 Identities = 19/83 (22%), Positives = 33/83 (39%), Gaps = 8/83 (9%)

Query: 5   FLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIAML 64
            LG G   KA++  L K G KV+V NR+    D     G      P +        I   
Sbjct: 123 ILGSGGSAKALACGLKKQGLKVSVLNRSPRGLDFFQRLGCDCFMEPPK--SAFDLII--- 177

Query: 65  SDPCAALSVVFDKGGVLEQICEG 87
               A  + + ++  + +++ +G
Sbjct: 178 ---NATSASLNNELPLNKEVLKG 197


>4OH1-A nrPDB
          Length = 351

 Score = 30.8 bits (68), Expect = 0.69,   Method: Composition-based stats.
 Identities = 21/115 (18%), Positives = 39/115 (33%), Gaps = 26/115 (22%)

Query: 7   GLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAE-------------- 52
           GLG+M   ++   L     +TV++    K +  +E+GA    + AE              
Sbjct: 184 GLGMMLVQLAR--LAGASTITVFDIVPEKLELALENGADYALNSAEEGVAERAIELAGGR 241

Query: 53  ---------VIKKCKYTIAMLS-DPCAALSVVFDKGGVLEQICEGKGYIDMSTVD 97
                         K  + +L+ D  A    ++ K  +L    +   Y D   + 
Sbjct: 242 YDCVLEGTGATAAAKLGLQLLARDGDAVYFAMYGKDPILPVNLQSDLYWDQKHIH 296


>1VC2-A nrPDB
          Length = 331

 Score = 30.4 bits (67), Expect = 0.81,   Method: Composition-based stats.
 Identities = 23/122 (18%), Positives = 41/122 (33%), Gaps = 6/122 (4%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWN-RTLSKCDELVEHGASVCESPAEVIKKCKY 59
           M+VG  G G +G+ +   L + G +V + N  T +K    +    S        +   + 
Sbjct: 1   MKVGINGFGRIGRQVFRILHERGVEVALINDLTDNKTLAHLLKYDSTYGRFPGAVGYDEE 60

Query: 60  TIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGR--FVE 117
            + +  D  A  +        +     G G +  ST       K   A    G +   + 
Sbjct: 61  NLYV--DGKAIRATAIKDPREIPWKQAGVGVVVESTGVFTDGEK-ARAHLEAGAKKVIIT 117

Query: 118 GP 119
            P
Sbjct: 118 AP 119


>1XDW-A nrPDB
          Length = 331

 Score = 30.4 bits (67), Expect = 0.87,   Method: Composition-based stats.
 Identities = 23/124 (18%), Positives = 46/124 (37%), Gaps = 17/124 (13%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62
           VG +GLG +G+  +      G  V   +    K  E          S  EV++K      
Sbjct: 149 VGVVGLGRIGRVAAQIFHGMGATVIGEDVFEIKGIE----DYCTQVSLDEVLEKSDIITI 204

Query: 63  ---MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAIT-----GKGGR 114
               + +  A ++  F     L+++ +G   ++ +      +  + EA+      G G  
Sbjct: 205 HAPYIKENGAVVTRDF-----LKKMKDGAILVNCARGQLVDTEAVIEAVESGKLGGYGCD 259

Query: 115 FVEG 118
            ++G
Sbjct: 260 VLDG 263


>1PS9-A nrPDB
          Length = 671

 Score = 30.4 bits (67), Expect = 0.96,   Method: Composition-based stats.
 Identities = 18/105 (17%), Positives = 35/105 (33%), Gaps = 9/105 (8%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNR--------TLSKCDELVEHGASVCESPAEVI 54
           +  +G G  G A ++N    G +VT+++          ++K     E           +I
Sbjct: 376 LAVVGAGPAGLAFAINAAARGHQVTLFDAHSEIGGQFNIAKQIPGKEEFYETLRYYRRMI 435

Query: 55  KKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAE 99
           +    T+ +     A     FD+  +   I      ID      +
Sbjct: 436 EVTGVTLKLNHTVTADQLQAFDETILASGIVPRTPPID-GIDHPK 479


>3PGJ-A nrPDB
          Length = 302

 Score = 30.4 bits (67), Expect = 1.0,   Method: Composition-based stats.
 Identities = 28/123 (22%), Positives = 48/123 (39%), Gaps = 16/123 (13%)

Query: 3   VGFLGLGIMGKAMSMNLLKNG-FKVTVWNRTLSKCDEL----VEHGASVCESPAEVIKKC 57
           +  +G G   + +   LL      +TV NRT +K ++L      +G    ++  ++ +  
Sbjct: 150 ILLIGAGGAARGVLKPLLDQQPASITVTNRTFAKAEQLAELVAAYGEVKAQAFEQLKQSY 209

Query: 58  KYTIAMLSDP-----CAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKI--NEAITG 110
              I   S        A   V+F    V   +  GKGY    TV  + + +    +AI G
Sbjct: 210 DVIINSTSASLDGELPAIDPVIFSSRSVCYDMMYGKGY----TVFNQWARQHGCAQAIDG 265

Query: 111 KGG 113
            G 
Sbjct: 266 LGM 268


>3DDL-A nrPDB
          Length = 273

 Score = 30.1 bits (66), Expect = 1.1,   Method: Composition-based stats.
 Identities = 11/46 (23%), Positives = 19/46 (41%), Gaps = 3/46 (6%)

Query: 12  GKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKC 57
           G  ++  L K G+ V ++N   +K +E    G +V E         
Sbjct: 231 GYTIADVLAKAGYGVLIYNIAKAKSEE---EGFNVSEMVEPATASA 273


>5NMX-A nrPDB
          Length = 425

 Score = 30.1 bits (66), Expect = 1.2,   Method: Composition-based stats.
 Identities = 11/30 (36%), Positives = 15/30 (50%)

Query: 2  EVGFLGLGIMGKAMSMNLLKNGFKVTVWNR 31
           V  LG G  G   +  L + GF+V V+ R
Sbjct: 3  RVAVLGAGPSGLTAARYLKQAGFEVMVFER 32


>5X6R-A nrPDB
          Length = 420

 Score = 30.1 bits (66), Expect = 1.2,   Method: Composition-based stats.
 Identities = 8/28 (28%), Positives = 17/28 (60%)

Query: 3  VGFLGLGIMGKAMSMNLLKNGFKVTVWN 30
          V  +G G++G   ++   K G+ VT+++
Sbjct: 31 VAIIGAGLVGCLAALAFSKEGYNVTLYD 58


>1DOH-A nrPDB
          Length = 283

 Score = 30.1 bits (66), Expect = 1.2,   Method: Composition-based stats.
 Identities = 25/157 (15%), Positives = 49/157 (31%), Gaps = 19/157 (12%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTV-WNRTLSKCDELVEH---GASVCESPAEVIKKCK 58
           V   G GI G+ M+M L + G KV V +  +    +E+V       S        +   +
Sbjct: 34  VTGAGRGI-GREMAMELGRRGCKVIVNYANSTESAEEVVAAIKKNGSDAACVKANVGVVE 92

Query: 59  YTIAMLSDPCAALS-----------VVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEA 107
             + M  +                 V F     +      + +   +      + +  + 
Sbjct: 93  DIVRMFEEAVKIFGKLDIVCSNSGVVSFGHVKDVTPEEFDRVFTINTRGQFFVAREAYKH 152

Query: 108 ITGKGGRFVEGPVSGSKKPAEDGQLIILAAGDKALFE 144
           +   G   + G ++G  K         + +G K   E
Sbjct: 153 LEIGGRLILMGSITGQAKAV---PKHAVYSGSKGAIE 186


>2WTB-A nrPDB
          Length = 725

 Score = 30.1 bits (66), Expect = 1.2,   Method: Composition-based stats.
 Identities = 9/46 (19%), Positives = 21/46 (45%), Gaps = 4/46 (8%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVC 47
           +V  +G G+MG  ++  L+ + + V +        ++ +E G    
Sbjct: 314 KVAIIGGGLMGSGIATALILSNYPVIL----KEVNEKFLEAGIGRV 355


>3W8X-A nrPDB
          Length = 468

 Score = 29.7 bits (65), Expect = 1.4,   Method: Composition-based stats.
 Identities = 13/91 (14%), Positives = 33/91 (36%), Gaps = 7/91 (7%)

Query: 28  VWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIAMLSDPCAALSVVFDKGGVLEQICEG 87
           +WN T+ +   L+    S        +   + +  +++      S+          +C+G
Sbjct: 40  IWNGTIDRRPALIARCTST-PDVVAAVSFARKSGLLVAVRGGGHSMAG------HSVCDG 92

Query: 88  KGYIDMSTVDAETSLKINEAITGKGGRFVEG 118
              ID+S +++    +       +GG  +  
Sbjct: 93  GIVIDLSLMNSIKVSRRLRRARAQGGCLLGA 123


>2E18-A nrPDB
          Length = 257

 Score = 29.7 bits (65), Expect = 1.4,   Method: Composition-based stats.
 Identities = 35/191 (18%), Positives = 57/191 (29%), Gaps = 28/191 (14%)

Query: 103 KINEAITGKGGRFVEGPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQ 162
           +I E I  KG   V   +SG    A    L   A G + +    +P F+        L  
Sbjct: 12  RILEFIREKGNNGVVIGISGGVDSATVAYLATKALGKEKVLGLIMPYFENKDVEDAKLVA 71

Query: 163 VGNGAKMKLIVNMIMGSMMNAFSEGLVL-ADKSGLS--------------SDTLLDILDL 207
              G   K+I    +  ++++F E L L  D+ GL               +++L  I+  
Sbjct: 72  EKLGIGYKVIN---IKPIVDSFVENLELNLDRKGLGNIMSRTRMIMLYAHANSLGRIVLG 128

Query: 208 GAMTNPMFKGKGPSMNKS--SYPPAFPLKHQQKDMRLALALGDENAVSMPVAAAANEAFK 265
            +  +    G           Y P   L   +        +     V         +   
Sbjct: 129 TSNRSEFLTGYFTKWGDGASDYAPIINLYKTE-----VWEIAKRIGVP---ERIVKKKPS 180

Query: 266 KARSLGLGDLD 276
                G  D D
Sbjct: 181 AGLWEGQTDED 191


>1BW9-B nrPDB
          Length = 356

 Score = 29.7 bits (65), Expect = 1.5,   Method: Composition-based stats.
 Identities = 14/104 (13%), Positives = 29/104 (27%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60
           + V   GLG +G +++    + G ++ V +    +    V  G +       +   C   
Sbjct: 177 LTVLVQGLGAVGGSLASLAAEAGAQLLVADTDTERVAHAVALGHTAVALEDVLSTPCDVF 236

Query: 61  IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKI 104
                       V       +          D +  D   +  I
Sbjct: 237 APCAMGGVITTEVARTLDCSVVAGAANNVIADEAASDILHARGI 280


>6APH-A nrPDB
          Length = 445

 Score = 29.7 bits (65), Expect = 1.5,   Method: Composition-based stats.
 Identities = 17/116 (14%), Positives = 32/116 (27%), Gaps = 9/116 (7%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61
            V   G G +GK  + +    G  VTV         +    G    +    V+      I
Sbjct: 228 RVVVCGFGDVGKGTAASFRGAGSIVTVTEIDPICALQAAMEGYE-VKQLDTVVDNADIII 286

Query: 62  AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVE 117
               +           G   E++ +     ++     +  + +       G   VE
Sbjct: 287 TTTGNFGIVR------GEHFEKMKDKTIVCNIG--HFDNEIDMAWLNKNHGATKVE 334


>3NT2-A nrPDB
          Length = 344

 Score = 29.7 bits (65), Expect = 1.6,   Method: Composition-based stats.
 Identities = 11/45 (24%), Positives = 18/45 (40%), Gaps = 3/45 (6%)

Query: 1  MEVGFLGLGIMGK---AMSMNLLKNGFKVTVWNRTLSKCDELVEH 42
          + +G +G G +GK       N L     V V +       ++VE 
Sbjct: 3  LRIGVIGTGAIGKEHINRITNKLSGAEIVAVTDVNQEAAQKVVEQ 47


>3WFI-A nrPDB
          Length = 312

 Score = 29.7 bits (65), Expect = 1.7,   Method: Composition-based stats.
 Identities = 14/61 (22%), Positives = 26/61 (42%)

Query: 1  MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60
          M++   G G MG    + L ++G +V + +       ++ EHG     +  EV  K    
Sbjct: 1  MKIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGLQANFNGKEVEAKLPIV 60

Query: 61 I 61
          +
Sbjct: 61 L 61


>1ZFN-A nrPDB
          Length = 253

 Score = 29.7 bits (65), Expect = 1.7,   Method: Composition-based stats.
 Identities = 8/27 (29%), Positives = 13/27 (48%)

Query: 2  EVGFLGLGIMGKAMSMNLLKNGFKVTV 28
          +V  +GLG +G   ++ L   G    V
Sbjct: 32 QVLIIGLGGLGTPAALYLAGAGVGTLV 58


>2EKL-A nrPDB
          Length = 313

 Score = 29.7 bits (65), Expect = 1.7,   Method: Composition-based stats.
 Identities = 14/94 (14%), Positives = 34/94 (36%), Gaps = 8/94 (8%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRT--LSKCDELVEHGASVCESPAEVIKKCKYT 60
           +G +G G +G  + +     G KV  ++      K +++         S  E++K     
Sbjct: 145 IGIVGFGRIGTKVGIIANAMGMKVLAYDILDIREKAEKINAK----AVSLEELLKNSDVI 200

Query: 61  IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMS 94
              ++    A  ++       E + +    ++ S
Sbjct: 201 SLHVTVSKDAKPIIDYPQ--FELMKDNVIIVNTS 232


>6ABI-A nrPDB
          Length = 358

 Score = 29.7 bits (65), Expect = 1.8,   Method: Composition-based stats.
 Identities = 14/110 (12%), Positives = 36/110 (32%), Gaps = 4/110 (3%)

Query: 4   GFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIAM 63
           G +G G +G+ +   L     KV  ++   +   ++ +       S  E+          
Sbjct: 173 GIIGTGKIGQILIKILRGFDMKVIAYDLFPN--QKVADELGFEYVSLDELYANSDIISLN 230

Query: 64  LSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGG 113
                    ++  +  +  ++ +G   ++        S  + EA+  K  
Sbjct: 231 CPLTKDTKYMINRRSML--KMKDGVILVNTGRGMLIDSADLVEALKDKKI 278


>3UP5-A nrPDB
          Length = 545

 Score = 29.3 bits (64), Expect = 1.8,   Method: Composition-based stats.
 Identities = 10/38 (26%), Positives = 17/38 (44%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDEL 39
            VG +G G  G  +     +   ++ V+ RT + C  L
Sbjct: 187 RVGVIGTGATGVQIIPIAAETAKELYVFQRTPNWCTPL 224


>3KTD-A nrPDB
          Length = 341

 Score = 29.3 bits (64), Expect = 1.9,   Method: Composition-based stats.
 Identities = 18/116 (15%), Positives = 35/116 (30%), Gaps = 2/116 (1%)

Query: 17  MNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVI--KKCKYTIAMLSDPCAALSVV 74
            +L      V  +NR+ S     V+ G  V       +     +  + +L+ P  A+  +
Sbjct: 25  RDLHAANHSVFGYNRSRSGAKSAVDEGFDVSADLEATLQRAAAEDALIVLAVPMTAIDSL 84

Query: 75  FDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSGSKKPAEDG 130
            D              + + T   +     N      G   + G  +     + DG
Sbjct: 85  LDAVHTHAPNNGFTDVVSVKTAVYDAVKARNMQHRYVGSHPMAGTANSGWSASMDG 140


>4PZE-A nrPDB
          Length = 284

 Score = 29.3 bits (64), Expect = 1.9,   Method: Composition-based stats.
 Identities = 22/108 (20%), Positives = 45/108 (41%), Gaps = 7/108 (6%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62
           VG +G G MG  ++      G  V + + +    D  V+ G +   S  + + K +    
Sbjct: 6   VGIVGAGTMGNGIAQACAVVGLNVVMVDIS----DAAVQKGVATVASSLDRLIKKEKLTE 61

Query: 63  MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITG 110
             +D  +AL+ +       + +      I+ +T + +  +KI + I G
Sbjct: 62  --ADKASALARIKG-STSYDDLKATDIVIEAATENYDLKVKILKQIDG 106


>2TMD-A nrPDB
          Length = 729

 Score = 29.3 bits (64), Expect = 1.9,   Method: Composition-based stats.
 Identities = 10/44 (22%), Positives = 21/44 (47%), Gaps = 1/44 (2%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASV 46
           V  +G G  G   +  L+++G+ V + + T  K    +   A++
Sbjct: 392 VLIVGAGPSGSEAARVLMESGYTVHLTD-TAEKIGGHLNQVAAL 434


>5BSH-A nrPDB
          Length = 277

 Score = 29.3 bits (64), Expect = 2.0,   Method: Composition-based stats.
 Identities = 41/249 (16%), Positives = 82/249 (32%), Gaps = 41/249 (16%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGF------KVTVWNRTLSKCDELVEHGASVCESPAEVIKK 56
           +GF+G G M ++++   +++G       K  + +   ++       G +V  S  +V++ 
Sbjct: 16  LGFIGAGKMAESIAKGAVRSGVLSPSRIKTAIHS-NPARRTAFESIGITVLSSNDDVVRD 74

Query: 57  CKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKG-GRF 115
               +  +  P     VV     +L +        D   V     +K+ +     G  RF
Sbjct: 75  SNVVVFSVK-PQLLKDVVLKLKPLLTK--------DKLLVSVAAGIKMKDLQEWAGHERF 125

Query: 116 VE-GPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGK----RSFYL----GQVGNG 166
           +   P + +        + +  A  +         F  +GK       Y     G  G+G
Sbjct: 126 IRVMPNTAATVGEAASVMSLGGAATEEDANLISQLFGSIGKIWKADDKYFDAITGLSGSG 185

Query: 167 AKMKLIVNMIMGSMMNAFSEGLVLADKSGLSSDTLLD-----ILDLGAMTNPMFKGKGPS 221
                     +   + A ++G      +GL  D  L      +L   +M     K  G  
Sbjct: 186 PAY-------IYLAIEALADG---GVAAGLPRDLALSLASQTVLGAASMATQSGKHPGQL 235

Query: 222 MNKSSYPPA 230
            +  + P  
Sbjct: 236 KDDVTSPGG 244


>2BW0-A nrPDB
          Length = 329

 Score = 29.3 bits (64), Expect = 2.0,   Method: Composition-based stats.
 Identities = 19/86 (22%), Positives = 33/86 (38%), Gaps = 6/86 (6%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKV----TVWNRTLSKCDELVEHGASVCESPAEVIKK 56
           M++  +G  + G+ +  +L K G +V    TV ++   K D L    A     P     +
Sbjct: 23  MKIAVIGQSLFGQEVYCHLRKEGHEVVGVFTVPDKD-GKADPLGLE-AEKDGVPVFKYSR 80

Query: 57  CKYTIAMLSDPCAALSVVFDKGGVLE 82
            +     L D  A    +  +  VL 
Sbjct: 81  WRAKGQALPDVVAKYQALGAELNVLP 106


>3J9R-A nrPDB
          Length = 386

 Score = 29.3 bits (64), Expect = 2.0,   Method: Composition-based stats.
 Identities = 19/140 (13%), Positives = 37/140 (26%), Gaps = 32/140 (22%)

Query: 27  TVWNRTLSKCDELVEHGASVCESPAEVIKK-------------------------CKYTI 61
            ++NR       +V  G    E+P                                +  +
Sbjct: 71  AIYNR---AQAVIVAVGVETAETPEAQASAVIGGISAAGERTGLQALLDGKSRFNAQPRL 127

Query: 62  AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121
            +     A  +V     G+ E++      +D      E ++   +    K    V+  V 
Sbjct: 128 LVAPGHSAQQAVATAMDGLAEKLRA-IAILDGPNSTDEAAVAYAKNFGSKRLFMVDPGVQ 186

Query: 122 ---GSKKPAEDGQLIILAAG 138
               +   A +      AAG
Sbjct: 187 VWDSATNAARNAPASAYAAG 206


>3K6J-A nrPDB
          Length = 460

 Score = 29.3 bits (64), Expect = 2.0,   Method: Composition-based stats.
 Identities = 11/36 (30%), Positives = 18/36 (50%)

Query: 3  VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDE 38
          V  +G G MGKAM++     G +  +  R   +C +
Sbjct: 57 VAIIGGGTMGKAMAICFGLAGIETFLVVRNEQRCKQ 92


>1HYH-A nrPDB
          Length = 309

 Score = 29.3 bits (64), Expect = 2.0,   Method: Composition-based stats.
 Identities = 17/78 (21%), Positives = 29/78 (37%), Gaps = 14/78 (17%)

Query: 2  EVGFLGLGIMGKAMSMNLLKNG----FKVTVWNRTLSKCDE---------LVEHGASVCE 48
          ++G +GLG +G A++  L+  G    +     N    K D+         L  HG  V  
Sbjct: 3  KIGIIGLGNVGAAVAHGLIAQGVADDYVFIDANEAKVKADQIDFQDAMANLEAHGNIVIN 62

Query: 49 SPAEVIKKCKYTIAMLSD 66
               +      I+ L +
Sbjct: 63 D-WAALADADVVISTLGN 79


>2CBN-A nrPDB
          Length = 306

 Score = 29.3 bits (64), Expect = 2.1,   Method: Composition-based stats.
 Identities = 19/124 (15%), Positives = 39/124 (31%), Gaps = 20/124 (16%)

Query: 66  DPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSG--- 122
           +  A  +     G + +++  GK      T+  E   +IN      G  ++  PV G   
Sbjct: 161 NAQALKAAGVPPGPLFQELKAGK------TITLEDGRQIN------GADYLAAPVPGKAL 208

Query: 123 ---SKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGS 179
                    D  L +    D  + E ++     +  ++   G         L     +G 
Sbjct: 209 AIFGDTGPCDAALDLAKGVDVMVHEATLDI--TMEAKANSRGHSSTRQAATLAREAGVGK 266

Query: 180 MMNA 183
           ++  
Sbjct: 267 LIIT 270


>4OVI-A nrPDB
          Length = 542

 Score = 29.3 bits (64), Expect = 2.2,   Method: Composition-based stats.
 Identities = 13/56 (23%), Positives = 21/56 (37%), Gaps = 2/56 (3%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKK 56
             VG +G G  G  +S  + K   ++ V+ RT           A +       +KK
Sbjct: 187 QRVGVIGTGSSGIQVSPQIAKQAAELFVFQRTPHFAVP--ARNAPLDPEFLADLKK 240


>3L9X-A nrPDB
          Length = 413

 Score = 29.3 bits (64), Expect = 2.2,   Method: Composition-based stats.
 Identities = 18/92 (19%), Positives = 30/92 (32%), Gaps = 8/92 (8%)

Query: 1  MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHG-------ASVCESPAEV 53
          M V   G G  G+     LL +G K+ V +      + L + G       A+  +     
Sbjct: 5  MRVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDATRMDLLESA 64

Query: 54 -IKKCKYTIAMLSDPCAALSVVFDKGGVLEQI 84
             K +  I  + DP   L +          +
Sbjct: 65 GAAKAEVLINAIDDPQTNLQLTEMVKEHFPHL 96


>4YRY-B nrPDB
          Length = 468

 Score = 28.9 bits (63), Expect = 2.6,   Method: Composition-based stats.
 Identities = 10/59 (16%), Positives = 21/59 (35%), Gaps = 7/59 (11%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60
           +V  +G G  G   + +L K G+ V ++       +   + G  +     E     +  
Sbjct: 142 KVAVVGSGPAGLTAAADLAKMGYHVDIF-------EAFHKPGGVLVYGIPEFRLPKRIV 193


>1E5Q-A nrPDB
          Length = 450

 Score = 28.9 bits (63), Expect = 2.7,   Method: Composition-based stats.
 Identities = 24/123 (19%), Positives = 42/123 (34%), Gaps = 21/123 (17%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEV--------- 53
           V  LG G + +     L  +G KVTV  RTL    +L         +P  +         
Sbjct: 6   VLMLGSGFVTRPTLDVLTDSGIKVTVACRTLESAKKLSA--GVQHSTPISLDVNDDAALD 63

Query: 54  --IKKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGK 111
             + K    I+++          F    +   I + K  +  S V     +++++A    
Sbjct: 64  AEVAKHDLVISLIPYT-------FHATVIKSAIRQKKHVVTTSYVSPAM-MELDQAAKDA 115

Query: 112 GGR 114
           G  
Sbjct: 116 GIT 118


>5U9P-A nrPDB
          Length = 265

 Score = 28.5 bits (62), Expect = 3.2,   Method: Composition-based stats.
 Identities = 6/65 (9%), Positives = 23/65 (35%), Gaps = 7/65 (10%)

Query: 12 GKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIAMLSDPCAAL 71
          G  ++  L + G  + + +R   K        A++     +      + +  +++     
Sbjct: 33 GLTLARGLAEAGAAIVINDRNEEKA-------ATLARRFRDEGFAADHAVFDVAEHAQVR 85

Query: 72 SVVFD 76
          + + +
Sbjct: 86 AAIDE 90


>3OSU-A nrPDB
          Length = 246

 Score = 28.5 bits (62), Expect = 3.4,   Method: Composition-based stats.
 Identities = 13/59 (22%), Positives = 28/59 (47%), Gaps = 4/59 (6%)

Query: 12 GKAMSMNLLKNGFKVTV-WNRTLSKCDELVEH-GASVCESPA--EVIKKCKYTIAMLSD 66
          G+++++ L + G+ V V +  +  K + +VE   A   +S A    +       AM+ +
Sbjct: 17 GRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVADADEVKAMIKE 75


>2DBZ-A nrPDB
          Length = 334

 Score = 28.5 bits (62), Expect = 3.5,   Method: Composition-based stats.
 Identities = 7/98 (7%), Positives = 40/98 (40%), Gaps = 4/98 (4%)

Query: 13  KAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIAMLSDPCAALS 72
           +A++        ++  ++RT    +E+     +  +   +++++  + +  +        
Sbjct: 163 QAIAKRAKGFNMRILYYSRTRK--EEVERELNAEFKPLEDLLRESDFVVLAVPLTRETYH 220

Query: 73  VVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITG 110
           ++ ++   L+ + +    I+++      +  + +A+  
Sbjct: 221 LINEER--LKLMKKTAILINIARGKVVDTNALVKALKE 256


>4J0E-A nrPDB
          Length = 320

 Score = 28.5 bits (62), Expect = 3.6,   Method: Composition-based stats.
 Identities = 9/40 (22%), Positives = 17/40 (42%)

Query: 3  VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEH 42
          V  +G G MG  ++     +GF V + +      D  ++ 
Sbjct: 17 VAIVGSGQMGSGIAQVTASSGFNVMLADVNKKALDRAMKA 56


>2PAJ-A nrPDB
          Length = 492

 Score = 28.5 bits (62), Expect = 3.6,   Method: Composition-based stats.
 Identities = 22/156 (14%), Positives = 45/156 (28%), Gaps = 6/156 (3%)

Query: 67  PCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSGSKKP 126
               + V  D+  +L Q   G  +   S     + +     +   G      PVS     
Sbjct: 283 YAHLVKVDADEIALLAQTGTGVAHCPQSNGRLGSGICPVREMADAGV-----PVSIGVDG 337

Query: 127 AEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMMNAFSE 186
           A   +   + +     +        +L + ++  G    GA    I  +I        + 
Sbjct: 338 AASNEAADMISEVHMTWLAQRARLGMLAQPAYRGGSFEGGAGAASIAEVIHWGT-AGGAR 396

Query: 187 GLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSM 222
            + L +   ++     DI          F    P++
Sbjct: 397 VMGLDEVGKVAVGYAADIAVYRLDDPRYFGLHDPAI 432


>2PB9-A nrPDB
          Length = 195

 Score = 28.5 bits (62), Expect = 3.8,   Method: Composition-based stats.
 Identities = 13/49 (26%), Positives = 24/49 (48%), Gaps = 3/49 (6%)

Query: 21  KNGFKVTVWNRTLSKCDELVEHGASV---CESPAEVIKKCKYTIAMLSD 66
           + GFKV+ ++R     +   + GA++    E+  + IK+    I  L D
Sbjct: 114 ERGFKVSFYDRREEPEEIKAKEGATIPWGIETAIKRIKERPDIIYHLGD 162


>6BMQ-A nrPDB
          Length = 523

 Score = 28.1 bits (61), Expect = 3.9,   Method: Composition-based stats.
 Identities = 10/33 (30%), Positives = 15/33 (45%)

Query: 21  KNGFKVTVWNRTLSKCDELVEHGASVCESPAEV 53
           + G KV + NRT  +  EL E       S  ++
Sbjct: 385 EKGAKVVIANRTYERALELAEAIGGKALSLTDL 417


>3ZV3-A nrPDB
          Length = 281

 Score = 28.1 bits (61), Expect = 4.0,   Method: Composition-based stats.
 Identities = 19/90 (21%), Positives = 34/90 (37%), Gaps = 9/90 (10%)

Query: 7  GLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDEL-VEHGASVCESPAEVIKKCKYTIAMLS 65
          G   +G+A+    +  G +V V +++  +  EL V HG +      +        +  L 
Sbjct: 13 GASGLGRALVDRFVAEGARVAVLDKSAERLRELEVAHGGNAVGVVGD--------VRSLQ 64

Query: 66 DPCAALSVVFDKGGVLEQICEGKGYIDMST 95
          D   A        G ++ +    G  D ST
Sbjct: 65 DQKRAAERCLAAFGKIDTLIPNAGIWDYST 94


>5EVJ-A nrPDB
          Length = 387

 Score = 28.1 bits (61), Expect = 4.2,   Method: Composition-based stats.
 Identities = 12/66 (18%), Positives = 21/66 (31%), Gaps = 2/66 (3%)

Query: 49  SPAEVIKKCKYTI-AMLSD-PCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINE 106
           S     K     + A L+D P       +  G  +    EG   +D+       +    +
Sbjct: 44  SACTAAKAPPPAVRAALADVPTEVKEKFWGCGNPIPAGIEGLRVLDLGAGSGRDAYVAAK 103

Query: 107 AITGKG 112
            +  KG
Sbjct: 104 LVGEKG 109


>6IHE-A nrPDB
          Length = 303

 Score = 28.1 bits (61), Expect = 4.4,   Method: Composition-based stats.
 Identities = 18/106 (16%), Positives = 41/106 (38%), Gaps = 5/106 (4%)

Query: 2   EVGFLGLGIMGKAMSMNLLKNGF--KVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKY 59
           +VGF+G G +G+ ++ + L +G   +  +++      D+          +  + IK    
Sbjct: 2   KVGFIGAGKIGQTIAYSALVSGAVDEAVIYDIIPELPDKFEHELRHAFAT--KGIKANVL 59

Query: 60  TIAMLSDPCAALSVVFDKGGV-LEQICEGKGYIDMSTVDAETSLKI 104
               L D      VV   G      +     ++D + +  + + K+
Sbjct: 60  GTNSLDDVSGMDIVVISAGKPRKPGMSRRDLFVDNAKIMIDLAQKL 105


>6J0Z-C nrPDB
          Length = 491

 Score = 28.1 bits (61), Expect = 4.8,   Method: Composition-based stats.
 Identities = 12/54 (22%), Positives = 20/54 (37%), Gaps = 1/54 (1%)

Query: 2  EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIK 55
          +V  +G G  G  ++  L   G  V V ++      E    G S   +  E  +
Sbjct: 7  DVVVVGAGPTGLMLAGELRLAGVSVVVLDKLAEPIKESRALGFS-ARTIEEFAQ 59


>1UB3-A nrPDB
          Length = 220

 Score = 28.1 bits (61), Expect = 5.0,   Method: Composition-based stats.
 Identities = 8/49 (16%), Positives = 17/49 (34%)

Query: 88  KGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSGSKKPAEDGQLIILA 136
           K  ++      E   ++ EA    G  F++       + A    + +L 
Sbjct: 122 KVILETGYFSPEEIARLAEAAIRGGADFLKTSTGFGPRGASLEDVALLV 170


>2DZB-A nrPDB
          Length = 294

 Score = 27.7 bits (60), Expect = 5.3,   Method: Composition-based stats.
 Identities = 19/184 (10%), Positives = 52/184 (28%), Gaps = 13/184 (7%)

Query: 95  TVDAETSLKINEAITGKGGRFVEGPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLG 154
            +D E +L+    +  +G   ++     ++  A    +       +      +P  + + 
Sbjct: 48  YLDPERALERAREMVAEGADILDLGAESTRPGAAPVPV-------EEEKRRLLPVLEAVL 100

Query: 155 K-----RSFYLGQVGNGAKMKLIVNMIMGSMMNAFSEGLVLADKSGLSSDTL-LDILDLG 208
                              +KL  +++           + LA + G+++  + + + D  
Sbjct: 101 SLGVPVSVDTRKPEVAEEALKLGAHLLNDVTGLRDERMVALAARHGVAAVVMHMPVPDPA 160

Query: 209 AMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDMRLALALGDENAVSMPVAAAANEAFKKAR 268
            M          +  K+               ++ L  G      +    A      +  
Sbjct: 161 TMMAHARYRDVVAEVKAFLEAQARRALSAGVPQVVLDPGFGFGKLLEHNLALLRRLDEIV 220

Query: 269 SLGL 272
           +LG 
Sbjct: 221 ALGH 224


>3WYE-A nrPDB
          Length = 256

 Score = 27.7 bits (60), Expect = 5.5,   Method: Composition-based stats.
 Identities = 19/97 (19%), Positives = 34/97 (35%), Gaps = 15/97 (15%)

Query: 3  VGFLGLGIMGKAMSMNLLKNGFKVTV--WNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60
          V   G GI GKA+++ L+K+GF V +  +N   +K          V     +        
Sbjct: 7  VTGAGQGI-GKAIALRLVKDGFAVAIADYNDATAKA---------VASEINQAGGHAVAV 56

Query: 61 IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVD 97
             +SD     + V      L         ++ + + 
Sbjct: 57 KVDVSDRDQVFAAVEQARKTLGGF---DVIVNNAGIA 90


>1PJB-A nrPDB
          Length = 361

 Score = 27.7 bits (60), Expect = 5.6,   Method: Composition-based stats.
 Identities = 13/85 (15%), Positives = 30/85 (35%), Gaps = 11/85 (12%)

Query: 15  MSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCE-------SPAEVIKKCKYTIAMLSDP 67
           M++ L   G +V +++  + +   L     S  E            + +    I  +  P
Sbjct: 185 MAVGL---GAQVQIFDINVERLSYLETLFGSRVELLYSNSAEIETAVAEADLLIGAVLVP 241

Query: 68  CAALSVVFDKGGVLEQICEGKGYID 92
               + +     ++EQ+  G   +D
Sbjct: 242 GR-RAPILVPASLVEQMRTGSVIVD 265


>5IOB-A nrPDB
          Length = 348

 Score = 27.7 bits (60), Expect = 5.9,   Method: Composition-based stats.
 Identities = 17/159 (10%), Positives = 37/159 (23%), Gaps = 21/159 (13%)

Query: 95  TVDAETSLKINE----AITGKGGRFVEGPV---------------SGSKKPAEDGQLIIL 135
           T+  E    + E     +   G      PV                 +            
Sbjct: 116 TMTPEQVEDLAEILGTGLAAHGVTVNFAPVVDVDAWGLPVVGDRSFSNDPAVAATYATAF 175

Query: 136 AAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMMNAFSEGLVLADKSG 195
           A G   +     P F          G       +   ++ +    +  + + L   D + 
Sbjct: 176 AKGLSKVG--ITPVFKHFPGHGRASGDSHTQDVVTPALDELKTYDLIPYGQALSETDGAV 233

Query: 196 LSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLK 234
           +    ++  L    + + +       +    YP   P  
Sbjct: 234 MVGHMIVPGLGTDGVPSSIDPATYQLLRSGDYPGGVPFD 272


>3HWR-A nrPDB
          Length = 318

 Score = 27.7 bits (60), Expect = 5.9,   Method: Composition-based stats.
 Identities = 12/97 (12%), Positives = 28/97 (28%), Gaps = 13/97 (13%)

Query: 1   MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASV------------CE 48
           M+V  +G G +G      L + G +V +  R       +   G  +              
Sbjct: 20  MKVAIMGAGAVGCYYGGMLARAGHEVILIAR-PQHVQAIEATGLRLETQSFDEQVKVSAS 78

Query: 49  SPAEVIKKCKYTIAMLSDPCAALSVVFDKGGVLEQIC 85
           S    ++     +  +       + +  K  + +   
Sbjct: 79  SDPSAVQGADLVLFCVKSTDTQSAALAMKPALAKSAL 115


>2DC1-A nrPDB
          Length = 236

 Score = 27.7 bits (60), Expect = 6.3,   Method: Composition-based stats.
 Identities = 11/27 (40%), Positives = 18/27 (66%)

Query: 1  MEVGFLGLGIMGKAMSMNLLKNGFKVT 27
          M VG +G G +GK ++  L +NGF++ 
Sbjct: 1  MLVGLIGYGAIGKFLAEWLERNGFEIA 27


>4OMU-A nrPDB
          Length = 283

 Score = 27.7 bits (60), Expect = 6.7,   Method: Composition-based stats.
 Identities = 18/100 (18%), Positives = 30/100 (30%), Gaps = 11/100 (11%)

Query: 19  LLKNGFKVTVWNRTLSKCDELVEH----GASVCESPAEVIKKCKYTIAMLSDPCAALSVV 74
           L      + + NRT+ K ++L       G  V    A + +     I   S   A    +
Sbjct: 139 LAHKPQSLVIANRTVEKAEQLAREFDELGPVVASGFAWLQEPVDVIINATSASLAGE--L 196

Query: 75  FDKGGVLEQICEGKGYI-DMSTVDAETSLKINEAITGKGG 113
                 L  +  G+    DM     +      +  T  G 
Sbjct: 197 PPIADSL--VEAGRTVCYDMMYG--KEPTPFCQWATKLGA 232


>5XGV-A nrPDB
          Length = 462

 Score = 27.4 bits (59), Expect = 6.9,   Method: Composition-based stats.
 Identities = 17/112 (15%), Positives = 35/112 (31%), Gaps = 2/112 (1%)

Query: 3   VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62
           V   G G +G  ++  L   G    V  R  +  +     G ++  +  E+  +     +
Sbjct: 4   VIIAGGGPVGLMLACELGLAGVDTVVLERHDAPREP--SRGGAINATVVELFTQRGIMES 61

Query: 63  MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGR 114
           +  D        F    +  +   G      +   A+   ++ E     G R
Sbjct: 62  LRDDGFEFRMAHFAHIPLAPERVPGDRAFSFAVPHAQVERRLEERARSLGVR 113


>1LSS-A nrPDB
          Length = 140

 Score = 27.4 bits (59), Expect = 7.0,   Method: Composition-based stats.
 Identities = 7/42 (16%), Positives = 18/42 (42%)

Query: 1  MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEH 42
          M +   G+G +G  ++ +L + G  + + +     C +    
Sbjct: 5  MYIIIAGIGRVGYTLAKSLSEKGHDIVLIDIDKDICKKASAE 46


>5UAU-A nrPDB
          Length = 322

 Score = 27.4 bits (59), Expect = 7.4,   Method: Composition-based stats.
 Identities = 13/71 (18%), Positives = 25/71 (35%), Gaps = 6/71 (8%)

Query: 1  MEVGFLGLGIMGKAMSMNLLKNG----FKVTVW--NRTLSKCDELVEHGASVCESPAEVI 54
          M VGF+G G +  A++      G     K+     +  L+    L + G  +     E +
Sbjct: 23 MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETV 82

Query: 55 KKCKYTIAMLS 65
          +        + 
Sbjct: 83 QHSDVLFLAVK 93


>2V3B-A nrPDB
          Length = 384

 Score = 27.4 bits (59), Expect = 7.4,   Method: Composition-based stats.
 Identities = 13/43 (30%), Positives = 19/43 (44%)

Query: 97  DAETSLKINEAITGKGGRFVEGPVSGSKKPAEDGQLIILAAGD 139
               +  +   + G G RF  GPV  S K A +G    L+ G+
Sbjct: 186 HPAAAKAVQAGLEGLGVRFHLGPVLASLKKAGEGLEAHLSDGE 228


>5CJE-A nrPDB
          Length = 393

 Score = 27.4 bits (59), Expect = 8.3,   Method: Composition-based stats.
 Identities = 14/68 (20%), Positives = 27/68 (39%), Gaps = 11/68 (16%)

Query: 13  KAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIAMLSDPCAALS 72
           +AM+  LL  G + TV          L+ +G     +  + +   +  + +L    A   
Sbjct: 224 RAMAFILLVAGHETTV---------NLITNGVHTLLTHPDQLAALRADMTLLD--GAVEE 272

Query: 73  VVFDKGGV 80
           V+  +G V
Sbjct: 273 VLRFEGPV 280


>2VDC-G nrPDB
          Length = 456

 Score = 27.4 bits (59), Expect = 8.6,   Method: Composition-based stats.
 Identities = 26/156 (16%), Positives = 47/156 (30%), Gaps = 28/156 (17%)

Query: 19  LLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIAMLSDPCAALSVVFDKG 78
           L   G++V V++R   +   L+ +G    +    V++     + +L+D        F+ G
Sbjct: 141 LRAKGYEVHVYDR-YDRMGGLLVYGIPGFKLEKSVVE---RRVKLLADAGVIYHPNFEVG 196

Query: 79  GVLEQICEGKGYIDMSTVDAETSLKINEAITGKG---GRFVEGPVSG-SKKPAEDGQLI- 133
                               E   K    +   G    R ++ P SG     A    L  
Sbjct: 197 RDASL--------------PELRRKHVAVLVATGVYKARDIKAPGSGLGNIVAALDYLTT 242

Query: 134 ---ILAAGDKALFEESIPAFDVLGKRSFYLGQVGNG 166
              +        +E    + +  GK    LG     
Sbjct: 243 SNKVSLGDTVEAYENG--SLNAAGKHVVVLGGGDTA 276


>2GRA-A nrPDB
          Length = 277

 Score = 27.4 bits (59), Expect = 8.6,   Method: Composition-based stats.
 Identities = 13/71 (18%), Positives = 25/71 (35%), Gaps = 6/71 (8%)

Query: 1  MEVGFLGLGIMGKAMSMNLLKNG----FKVTVW--NRTLSKCDELVEHGASVCESPAEVI 54
          M VGF+G G +  A++      G     K+     +  L+    L + G  +     E +
Sbjct: 3  MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETV 62

Query: 55 KKCKYTIAMLS 65
          +        + 
Sbjct: 63 QHSDVLFLAVK 73


>4HB9-A nrPDB
          Length = 412

 Score = 27.0 bits (58), Expect = 9.0,   Method: Composition-based stats.
 Identities = 10/43 (23%), Positives = 22/43 (51%)

Query: 15 MSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKC 57
          ++  L K+G KVT++ R  +    L  +G  +     + +++C
Sbjct: 16 LAHGLRKHGIKVTIYERNSAASSILPGYGIHINSFGKQALQEC 58


>4Y4N-A nrPDB
          Length = 286

 Score = 27.0 bits (58), Expect = 9.3,   Method: Composition-based stats.
 Identities = 10/31 (32%), Positives = 16/31 (51%)

Query: 1  MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNR 31
          ++V  +G G  G   +  + K G+KV V  R
Sbjct: 53 VDVAIVGGGPSGLTAARYIAKEGYKVVVLER 83


  Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
    Posted date:  Jan 3, 2023  9:05 PM
  Number of letters in database: 10,336,785
  Number of sequences in database:  36,641
  
Lambda     K      H
   0.305    0.131    0.313 

Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,131,066
Number of Sequences: 36641
Number of extensions: 331912
Number of successful extensions: 1744
Number of sequences better than 10.0: 255
Number of HSP's better than 10.0 without gapping: 198
Number of HSP's successfully gapped in prelim test: 122
Number of HSP's that attempted gapping in prelim test: 1421
Number of HSP's gapped (non-prelim): 336
length of query: 289
length of database: 10,336,785
effective HSP length: 96
effective length of query: 193
effective length of database: 6,819,249
effective search space: 1316115057
effective search space used: 1316115057
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.0 bits)
S2: 59 (27.3 bits)