BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9LSV0 (289 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3DOJ-A nrPDB 585 e-168 3PDU-A nrPDB 328 1e-90 3PEF-A nrPDB 326 8e-90 2UYY-A nrPDB 278 2e-75 5XVH-A nrPDB 162 2e-40 3CKY-A nrPDB 144 3e-35 1VPD-A nrPDB 138 2e-33 1YB4-A nrPDB 131 3e-31 5JE8-A nrPDB 120 8e-28 4DLL-A nrPDB 117 5e-27 2GF2-A nrPDB 109 1e-24 4GBJ-A nrPDB 95 3e-20 5Y8M-A nrPDB 89 2e-18 2CVZ-A nrPDB 89 2e-18 3Q3C-A nrPDB 86 2e-17 4D3S-A nrPDB 81 6e-16 4D3F-A nrPDB 80 1e-15 3G0O-A nrPDB 78 4e-15 3QHA-A nrPDB 77 1e-14 4OQZ-A nrPDB 74 7e-14 5OCM-A nrPDB 73 2e-13 3ZHB-A nrPDB 73 2e-13 5U5G-A nrPDB 68 6e-12 5G6R-A nrPDB 66 2e-11 4OQY-A nrPDB 65 4e-11 5A9T-A nrPDB 64 1e-10 3L6D-A nrPDB 59 3e-09 2W8Z-A nrPDB 50 8e-07 6EOI-A nrPDB 49 2e-06 2ZYA-A nrPDB 49 2e-06 2IZ1-A nrPDB 45 4e-05 6FQY-A nrPDB 44 1e-04 4E21-A nrPDB 42 2e-04 1PGJ-A nrPDB 40 0.002 2P4Q-A nrPDB 39 0.004 4GWK-A nrPDB 38 0.005 1PGO-A nrPDB 38 0.006 2HK7-A nrPDB 36 0.015 4YPO-A nrPDB 35 0.056 4DGS-A nrPDB 33 0.10 6C6P-A nrPDB 32 0.23 2D0I-A nrPDB 32 0.30 4WEQ-A nrPDB 31 0.51 2F1K-A nrPDB 31 0.51 6C55-A nrPDB 31 0.58 3PGJ-A nrPDB 31 0.76 1TXG-A nrPDB 30 0.81 5TSD-A nrPDB 30 1.7 3K96-A nrPDB 29 2.5 4N18-A nrPDB 29 3.0 1BG6-A nrPDB 28 3.6 1T0K-B nrPDB 28 3.7 5JOY-A nrPDB 28 4.1 6IUM-B nrPDB 28 5.6 3GGO-A nrPDB 28 6.2 2G5C-A nrPDB 28 6.6 4XA8-A nrPDB 27 9.2 >3DOJ-A nrPDB Length = 310 Score = 585 bits (1508), Expect = e-168, Method: Compositional matrix adjust. Identities = 289/289 (100%), Positives = 289/289 (100%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT Sbjct: 22 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 81 Query: 61 IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120 IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV Sbjct: 82 IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 141 Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 180 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM Sbjct: 142 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 201 Query: 181 MNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDM 240 MNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDM Sbjct: 202 MNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDM 261 Query: 241 RLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVKFSRE 289 RLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVKFSRE Sbjct: 262 RLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVKFSRE 310 >3PDU-A nrPDB Length = 287 Score = 328 bits (842), Expect = 1e-90, Method: Compositional matrix adjust. Identities = 164/282 (58%), Positives = 198/282 (70%) Query: 4 GFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIAM 63 GFLGLGIMG M+ NL++ GF VTVWNR +KC LV GA SPAEV C TIAM Sbjct: 5 GFLGLGIMGGPMAANLVRAGFDVTVWNRNPAKCAPLVALGARQASSPAEVCAACDITIAM 64 Query: 64 LSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSGS 123 L+DP AA V F GVLE I G+GYIDMSTVD ETS I A+T +GGRF+E PVSG+ Sbjct: 65 LADPAAAREVCFGANGVLEGIGGGRGYIDMSTVDDETSTAIGAAVTARGGRFLEAPVSGT 124 Query: 124 KKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMMNA 183 KKPAEDG LIILAAGD++LF ++ PAF LGK+ +LG+VG GA+MKL+VNMIMG MM A Sbjct: 125 KKPAEDGTLIILAAGDQSLFTDAGPAFAALGKKCLHLGEVGQGARMKLVVNMIMGQMMTA 184 Query: 184 FSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDMRLA 243 EG+ L GL LL++LD GAM NPMFKGKG + +P +FPLKH QKD+RLA Sbjct: 185 LGEGMALGRNCGLDGGQLLEVLDAGAMANPMFKGKGQMLLSGEFPTSFPLKHMQKDLRLA 244 Query: 244 LALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVK 285 + LGD + AA ANE+FK+AR+ G D DF+AV ++ Sbjct: 245 VELGDRLGQPLHGAATANESFKRARAAGHADEDFAAVFRVLE 286 >3PEF-A nrPDB Length = 287 Score = 326 bits (835), Expect = 8e-90, Method: Compositional matrix adjust. Identities = 159/279 (56%), Positives = 203/279 (72%) Query: 4 GFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIAM 63 GF+GLGIMG AM+ NL+K G VT+WNR+ K +EL GA +P EV++ C T AM Sbjct: 5 GFIGLGIMGSAMAKNLVKAGCSVTIWNRSPEKAEELAALGAERAATPCEVVESCPVTFAM 64 Query: 64 LSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSGS 123 L+DP AA V F K GVLE I EG+GY+DMSTVD TS +I A+ KGGRF+E PVSGS Sbjct: 65 LADPAAAEEVCFGKHGVLEGIGEGRGYVDMSTVDPATSQRIGVAVVAKGGRFLEAPVSGS 124 Query: 124 KKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMMNA 183 KKPAEDG LIILAAGD+ L++E++P F+ +GK+ +LG VG GA+MKL+VNM+MG MM Sbjct: 125 KKPAEDGTLIILAAGDRNLYDEAMPGFEKMGKKIIHLGDVGKGAEMKLVVNMVMGGMMAC 184 Query: 184 FSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDMRLA 243 F EGL L +K+GL++D +LD++ GAM NPMF KG + ++ PAFPLKH QKD+RLA Sbjct: 185 FCEGLALGEKAGLATDAILDVIGAGAMANPMFALKGGLIRDRNFAPAFPLKHMQKDLRLA 244 Query: 244 LALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIE 282 +ALGD + +AAANE FK AR+ G GD DFSA+ + Sbjct: 245 VALGDRVGQPLVASAAANELFKGARAAGFGDEDFSAIFK 283 >2UYY-A nrPDB Length = 316 Score = 278 bits (710), Expect = 2e-75, Method: Compositional matrix adjust. Identities = 140/282 (49%), Positives = 189/282 (67%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61 ++GFLGLG+MG + NLLK G VTVWNRT KCD ++ GA + +PAEV+ C T Sbjct: 32 KIGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKCDLFIQEGARLGRTPAEVVSTCDITF 91 Query: 62 AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121 A +SDP AA +V GVL+ I GK Y+DMSTVDA+T ++ + I +GGRF+E PVS Sbjct: 92 ACVSDPKAAKDLVLGPSGVLQGIRPGKCYVDMSTVDADTVTELAQVIVSRGGRFLEAPVS 151 Query: 122 GSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMM 181 G+++ + DG L+ILAAGD+ L+E+ F +GK SF+LG+VGN AKM LIVNM+ GS M Sbjct: 152 GNQQLSNDGMLVILAAGDRGLYEDCSSCFQAMGKTSFFLGEVGNAAKMMLIVNMVQGSFM 211 Query: 182 NAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDMR 241 +EGL LA +G S TLLDIL+ G + + K ++ + ++ P F LK+ QKD+R Sbjct: 212 ATIAEGLTLAQVTGQSQQTLLDILNQGQLASIFLDQKCQNILQGNFKPDFYLKYIQKDLR 271 Query: 242 LALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEA 283 LA+ALGD P+AAAANE +K+A++L D D SAV A Sbjct: 272 LAIALGDAVNHPTPMAAAANEVYKRAKALDQSDNDMSAVYRA 313 >5XVH-A nrPDB Length = 306 Score = 162 bits (409), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 99/280 (35%), Positives = 142/280 (50%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60 M VGF+GLGIMG M+ +LLK GF V+NRT K E G V ESPA++ K+ Sbjct: 21 MRVGFIGLGIMGGPMATHLLKAGFLAAVYNRTREKTKPFAEAGVYVAESPADLAKRVDVV 80 Query: 61 IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120 I M+SD V+F GV+E G +DMST + + K E + G F++ PV Sbjct: 81 IVMVSDAPDVEQVLFGPSGVVEGARPGLIVVDMSTNSPDWARKFAERLAQYGIEFLDAPV 140 Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 180 +G +K A +G L I+ G + LF +P F +G+ Y+G VG G MKL+ +++ Sbjct: 141 TGGQKGAIEGTLTIMVGGKEELFHRLLPIFKAMGRDIVYMGPVGYGQAMKLVNQVVVALN 200 Query: 181 MNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDM 240 A EGL LA GL D + ++L GA + + P + K P F +H +KD+ Sbjct: 201 TVAMVEGLKLAKALGLDMDKVAEVLTRGAARSGAIELYLPKLLKGDLSPGFKAEHLKKDL 260 Query: 241 RLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAV 280 L + V +P A A E ++K G G L A+ Sbjct: 261 GYVLEEARKRGVKLPGAELAYELYRKMVEDGAGSLGIHAL 300 >3CKY-A nrPDB Length = 301 Score = 144 bits (364), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 95/283 (33%), Positives = 151/283 (53%), Gaps = 1/283 (0%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60 +++GF+GLG MGK M++NLLK G V ++ + +V GA CE+ +V Sbjct: 5 IKIGFIGLGAMGKPMAINLLKEGVTVYAFDLMEANVAAVVAQGAQACENNQKVAAASDII 64 Query: 61 IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120 L + +V+ GGVL G +DMS+V ++LK+ + KG +V+ PV Sbjct: 65 FTSLPNAGIVETVMNGPGGVLSACKAGTVIVDMSSVSPSSTLKMAKVAAEKGIDYVDAPV 124 Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 180 SG K AE G L I+ +A+FE+ P V+GK +++G G G +K++ N+++G Sbjct: 125 SGGTKGAEAGTLTIMVGASEAVFEKIQPVLSVIGKDIYHVGDTGAGDAVKIVNNLLLGCN 184 Query: 181 MNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSS-YPPAFPLKHQQKD 239 M + +E LVL K GL +T+ +I+ + + + K S + F + Q KD Sbjct: 185 MASLAEALVLGVKCGLKPETMQEIIGKSSGRSYAMEAKMEKFIMSGDFAGGFAMDLQHKD 244 Query: 240 MRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIE 282 + LAL G E V +P+ A A + F+ R++GLG D SAVI+ Sbjct: 245 LGLALEAGKEGNVPLPMTAMATQIFEGGRAMGLGREDMSAVIK 287 >1VPD-A nrPDB Length = 299 Score = 138 bits (348), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 86/280 (30%), Positives = 140/280 (50%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60 M+VGF+GLGIMGK MS NLLK G+ + V +R +++ GA + + ++C Sbjct: 6 MKVGFIGLGIMGKPMSKNLLKAGYSLVVSDRNPEAIADVIAAGAETASTAKAIAEQCDVI 65 Query: 61 IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120 I ML + V + G++E G IDMS++ S +I++A+ KG ++ PV Sbjct: 66 ITMLPNSPHVKEVALGENGIIEGAKPGTVLIDMSSIAPLASREISDALKAKGVEMLDAPV 125 Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 180 SG + A DG L ++ GDKA+F++ + + G +G G KL +I+ Sbjct: 126 SGGEPKAIDGTLSVMVGGDKAIFDKYYDLMKAMAGSVVHTGDIGAGNVTKLANQVIVALN 185 Query: 181 MNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDM 240 + A SE L LA K+G++ D + + G + + K P + ++ P F + KD+ Sbjct: 186 IAAMSEALTLATKAGVNPDLVYQAIRGGLAGSTVLDAKAPMVMDRNFKPGFRIDLHIKDL 245 Query: 241 RLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAV 280 AL +P+ AA E + R+ G G+ D SA+ Sbjct: 246 ANALDTSHGVGAQLPLTAAVMEMMQALRADGHGNDDHSAL 285 >1YB4-A nrPDB Length = 295 Score = 131 bits (329), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 85/287 (29%), Positives = 146/287 (50%), Gaps = 3/287 (1%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSK-CDELVEHGASVCESPAEVIKKCKY 59 M++GF+GLGIMG M++NL + G ++ V T+ DEL+ GA E+ +V + Sbjct: 4 MKLGFIGLGIMGSPMAINLARAGHQLHVT--TIGPVADELLSLGAVNVETARQVTEFADI 61 Query: 60 TIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGP 119 M+ D V+F + G + +GK +DMS++ + + + + G +++ P Sbjct: 62 IFIMVPDTPQVEDVLFGEHGCAKTSLQGKTIVDMSSISPIETKRFAQRVNEMGADYLDAP 121 Query: 120 VSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGS 179 VSG + A +G L I+ G++ +F+ P FD+LGK +G G+G K+ +I+ Sbjct: 122 VSGGEIGAREGTLSIMVGGEQKVFDRVKPLFDILGKNITLVGGNGDGQTCKVANQIIVAL 181 Query: 180 MMNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKD 239 + A SE LV A K+G + L G ++ + + G M ++ P F + QKD Sbjct: 182 NIEAVSEALVFASKAGADPVRVRQALMGGFASSRILEVHGERMINRTFEPGFKIALHQKD 241 Query: 240 MRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVKF 286 + LAL A+++P A E F + G LD SA+++A++ Sbjct: 242 LNLALQSAKALALNLPNTATCQELFNTCAANGGSQLDHSAMVQALEL 288 >5JE8-A nrPDB Length = 302 Score = 120 bits (300), Expect = 8e-28, Method: Compositional matrix adjust. Identities = 85/287 (29%), Positives = 146/287 (50%), Gaps = 6/287 (2%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDE--LVEHGASVCESPAEVIKKCKY 59 ++GF+GLG MG MS NL+K+G+ TV+ L+K E + G + S +++ + C Sbjct: 9 KIGFIGLGNMGLPMSKNLVKSGY--TVYGVDLNKEAEASFEKEGGIIGLSISKLAETCDV 66 Query: 60 TIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGP 119 L P A +V F G+ E +ID STV + + ++ EA K F+ P Sbjct: 67 VFTSLPSPRAVEAVYFGAEGLFENGHSNVVFIDTSTVSPQLNKQLEEAAKEKKVDFLAAP 126 Query: 120 VSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLG-QVGNGAKMKLIVNMIMG 178 VSG AE+ L + G K ++E++ VLG F++ Q+ +G +KLI N+++G Sbjct: 127 VSGGVIGAENRTLTFMVGGSKDVYEKTESIMGVLGANIFHVSEQIDSGTTVKLINNLLIG 186 Query: 179 SMMNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPS-MNKSSYPPAFPLKHQQ 237 SE L LA K+ + D + DIL++ + +++ S + +Y P F + + Sbjct: 187 FYTAGVSEALTLAKKNNMDLDKMFDILNVSYGQSRIYERNYKSFIAPENYEPGFTVNLLK 246 Query: 238 KDMRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAV 284 KD+ A+ L E+ + +PV+ + +A G G+ D +A+ + V Sbjct: 247 KDLGFAVDLAKESELHLPVSEMLLNVYDEASQAGYGENDMAALYKKV 293 >4DLL-A nrPDB Length = 320 Score = 117 bits (294), Expect = 5e-27, Method: Compositional matrix adjust. Identities = 82/280 (29%), Positives = 132/280 (47%), Gaps = 2/280 (0%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61 ++ FLG G MG M+ L + G+ + VWNRT ++ L GA++ E + + Sbjct: 33 KITFLGTGSMGLPMARRLCEAGYALQVWNRTPARAASLAALGATIHEQARAAARDADIVV 92 Query: 62 AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121 +ML + V+F +G V + G ++DM+++ + + G ++ PVS Sbjct: 93 SMLENGAVVQDVLFAQG-VAAAMKPGSLFLDMASITPREARDHAARLGALGIAHLDTPVS 151 Query: 122 GSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMM 181 G AE G L+I+A G A FE S+P V G R+ ++G G+G KL MI+G + Sbjct: 152 GGTVGAEQGTLVIMAGGKPADFERSLPLLKVFG-RATHVGPHGSGQLTKLANQMIVGITI 210 Query: 182 NAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDMR 241 A +E L+ A K G + + + G + + + G M + + P L Q KDMR Sbjct: 211 GAVAEALLFATKGGADMAKVKEAITGGFADSRVLQLHGQRMVERDFAPRARLSIQLKDMR 270 Query: 242 LALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVI 281 ALA E P+ + + + GL DLD S + Sbjct: 271 NALATAQEIGFDAPITGLFEQLYAEGVEHGLTDLDQSGLF 310 >2GF2-A nrPDB Length = 296 Score = 109 bits (273), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 84/298 (28%), Positives = 135/298 (45%), Gaps = 14/298 (4%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60 M VGF+GLG MG M+ NL+K+G+ + +++ C E + G V SPA+V +K Sbjct: 1 MPVGFIGLGNMGNPMAKNLMKHGYPLIIYDVFPDACKEFQDAGEQVVSSPADVAEKADRI 60 Query: 61 IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120 I ML A+ G+L+++ +G ID ST+D S ++ + + G F++ PV Sbjct: 61 ITMLPTSINAIEAYSGANGILKKVKKGSLLIDSSTIDPAVSKELAKEVEKMGAVFMDAPV 120 Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 180 SG A G L + G + F + +G Y G VG G K+ NM++ Sbjct: 121 SGGVGAARSGNLTFMVGGVEDEFAAAQELLGCMGSNVVYCGAVGTGQAAKICNNMLLAIS 180 Query: 181 MNAFSEGLVLADKSGLSSDTLLDILDLGA-------MTNPM--FKGKGPSMNKSSYPPAF 231 M +E + L + GL L IL++ + NP+ PS N +Y F Sbjct: 181 MIGTAEAMNLGIRLGLDPKLLAKILNMSSGRCWSSDTYNPVPGVMDGVPSAN--NYQGGF 238 Query: 232 PLKHQQKDMRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVKFSRE 289 KD+ LA + + + A++ ++ + G DFS+V + F RE Sbjct: 239 GTTLMAKDLGLAQDSATSTKSPILLGSLAHQIYRMMCAKGYSKKDFSSVFQ---FLRE 293 >4GBJ-A nrPDB Length = 297 Score = 95.1 bits (235), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 73/281 (25%), Positives = 132/281 (46%), Gaps = 4/281 (1%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61 ++ FLGLG +G ++ LL+ G+++ VWNRT SK + L + GA+V E+ + I Sbjct: 7 KIAFLGLGNLGTPIAEILLEAGYELVVWNRTASKAEPLTKLGATVVENAIDAITPGGIVF 66 Query: 62 AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121 ++L+D AA+ +F ++E++ + ++ MST+ ETS ++ + G +V P+ Sbjct: 67 SVLADD-AAVEELFSM-ELVEKLGKDGVHVSMSTISPETSRQLAQVHEWYGAHYVGAPIF 124 Query: 122 GSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLG-QVGNGAKMKLIVNMIMGSM 180 + I +G+ E P + K F G G +KL N ++ Sbjct: 125 ARPEAVRAKVGNICLSGNAGAKERIKPIVENFVKGVFDFGDDPGAANVIKLAGNFMIACS 184 Query: 181 MNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPP-AFPLKHQQKD 239 + E +A+K+G+S ++ ++L P+F+ G + ++Y P AF KD Sbjct: 185 LEMMGEAFTMAEKNGISRQSIYEMLTSTLFAAPIFQNYGKLVASNTYEPVAFRFPLGLKD 244 Query: 240 MRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAV 280 + L L + MP A F + G +LD+ A+ Sbjct: 245 INLTLQTASDVNAPMPFADIIRNRFISGLAKGRENLDWGAL 285 >5Y8M-A nrPDB Length = 295 Score = 89.0 bits (219), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 78/290 (26%), Positives = 123/290 (42%), Gaps = 11/290 (3%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62 + FLGLG MG MS NL+ G V ++ + HG +V S E + + I Sbjct: 5 IAFLGLGNMGAPMSANLVGAGHVVRGFDPAPTAASGAAAHGVAVFRSAPEAVAEADVVIT 64 Query: 63 MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSG 122 ML D VL +ID ST+ + +++ G ++ PVSG Sbjct: 65 MLPTGEVVRRCYTD---VLAAARPATLFIDSSTISVTDAREVHALAESHGMLQLDAPVSG 121 Query: 123 SKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMMN 182 K A L + GD++ + P + + + + G G G K+ NM++ Sbjct: 122 GVKGAAAATLAFMVGGDESTLRRARPVLEPMAGKIIHCGAAGAGQAAKVCNNMVLAVQQI 181 Query: 183 AFSEGLVLADKSGLSSDTLLDILD------LGAMTNPMFKGKGP-SMNKSSYPPAFPLKH 235 A +E VLA+K GLS+ +L D++ TN G P S + + P F Sbjct: 182 AIAEAFVLAEKLGLSAQSLFDVITGATGNCWAVHTNCPVPGPVPTSPANNDFKPGFSTAL 241 Query: 236 QQKDMRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVK 285 KD+ LA+ + P+ + A + + K + DLDFSAVI ++ Sbjct: 242 MNKDLGLAMDAVAATGATAPLGSHAADIYAK-FAADHADLDFSAVIHTLR 290 >2CVZ-A nrPDB Length = 289 Score = 89.0 bits (219), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 73/272 (26%), Positives = 125/272 (45%), Gaps = 8/272 (2%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61 +V F+GLG MG M+ +L + F VWNRT K E S P E + + + Sbjct: 3 KVAFIGLGAMGYPMAGHLARR-FPTLVWNRTFEKALRHQEEFGSEA-VPLERVAEARVIF 60 Query: 62 AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121 L V + + EG ++D ++ + E S ++ E + KG +++ PVS Sbjct: 61 TCLPTTREVYEVA---EALYPYLREGTYWVDATSGEPEASRRLAERLREKGVTYLDAPVS 117 Query: 122 GSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMM 181 G AE G L ++ G + E P F K+ ++G VG G +K I N ++ + Sbjct: 118 GGTSGAEAGTLTVMLGGPEEAVERVRP-FLAYAKKVVHVGPVGAGHAVKAINNALLAVNL 176 Query: 182 NAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPS-MNKSSYPPAFPLKHQQKDM 240 A EGL+ K G+S++ L++++ + + + P + ++P F L KD+ Sbjct: 177 WAAGEGLLALVKQGVSAEKALEVINASSGRSNATENLIPQRVLTRAFPKTFALGLLVKDL 236 Query: 241 RLALALGDENAVSMPVAAAANEAFKKA-RSLG 271 +A+ + D P+ A E ++ A R LG Sbjct: 237 GIAMGVLDGEKAPSPLLRLAREVYEMAKRELG 268 >3Q3C-A nrPDB Length = 299 Score = 85.9 bits (211), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 61/204 (29%), Positives = 101/204 (49%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61 ++ F+GLG MG M+ NLLK G+ + V++ S D LV GAS S + ++ I Sbjct: 4 QIAFIGLGHMGAPMATNLLKAGYLLNVFDLVQSAVDGLVAAGASAARSARDAVQGADVVI 63 Query: 62 AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121 +ML + D G+L I G ++ ST+ ++ KI+ A +G ++ PVS Sbjct: 64 SMLPASQHVEGLYLDDDGLLAHIAPGTLVLECSTIAPTSARKIHAAARERGLAMLDAPVS 123 Query: 122 GSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMM 181 G A G L + GD E++ P F+ +G+ F+ G G G K+ N ++ +M Sbjct: 124 GGTAGAAAGTLTFMVGGDAEALEKARPLFEAMGRNIFHAGPDGAGQVAKVCNNQLLAVLM 183 Query: 182 NAFSEGLVLADKSGLSSDTLLDIL 205 +E + L +GL + L +I+ Sbjct: 184 IGTAEAMALGVANGLEAKVLAEIM 207 >4D3S-A nrPDB Length = 293 Score = 80.9 bits (198), Expect = 6e-16, Method: Compositional matrix adjust. Identities = 69/270 (25%), Positives = 117/270 (43%), Gaps = 23/270 (8%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62 V +GLG MG+AM+ LL+ G+++TVWNRT +K + L E GA+V +SPAE ++ + Sbjct: 11 VTLIGLGPMGQAMAGALLEAGYELTVWNRTKAKAEALAERGAAVADSPAEALRAGGPVLL 70 Query: 63 MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSG 122 L++ V+ +G E +G+ +++ + S G G R+V G V Sbjct: 71 SLTEHAVMYRVL--EGA--ESDLKGRTILNLGSDTPAASRAAAAWAEGHGARYVTGGVMS 126 Query: 123 SKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMMN 182 + +GD+A FEE+ +VL F G I+ + + M Sbjct: 127 PAPGIGSSSVFSFYSGDRAAFEENKALLEVLTATDFRGEDPGLAQVYYQILLDLFWTTMT 186 Query: 183 AFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDMRL 242 + L +A G+ T+ L G F+G ++ + +P Sbjct: 187 GYLHALAVARAEGVPVGTITPYLIEGNDMAMFFEGTSAAVAEGRFP-------------- 232 Query: 243 ALALGDENAVSMPVAAAANEAFKKARSLGL 272 GDE+ +SM AA+ + +R G+ Sbjct: 233 ----GDEDRISMD-AASMEHVVQTSRDAGV 257 >4D3F-A nrPDB Length = 310 Score = 79.7 bits (195), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 76/299 (25%), Positives = 130/299 (43%), Gaps = 30/299 (10%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62 V +GLG MG+AM+ L+ G+ VTVWNRT SK D+LV GA + E + + I Sbjct: 24 VTVIGLGPMGQAMADVFLEYGYSVTVWNRTSSKADQLVAKGAIRVSTVNEALAANELVIL 83 Query: 63 MLSDPCAALSVVFDKGGVLEQICE---GKGYIDMSTVDAETSLKINEAITGKGGRFVEGP 119 L+D S +LE + E GK +++S+ E + K + + +G R + G Sbjct: 84 SLTDYNVMYS-------ILEPVSENLFGKVLVNLSSDTPEKARKAAKWLEDRGARHITGG 136 Query: 120 VSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNM-IMG 178 V + +GD+ +FE +VL S Y G+ A + + M I Sbjct: 137 VQVPPSGIGKSESYTYYSGDRVVFEAHRETLEVL-TSSDYRGEDPGLAMLYYQIQMDIFW 195 Query: 179 SMMNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMF-KGKGPSMNKSSYPPAFPLKHQQ 237 + M ++ L +A+ +G++++ L + P F + P +++ +P Sbjct: 196 TAMLSYLHALAIANANGITAEQFLPYASAMMSSLPKFVEFYTPRLDEGEHPGDVD----- 250 Query: 238 KDMRLALALG---------DENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVKFS 287 RLA+ L E + + + A E F++ G F+++IE K S Sbjct: 251 ---RLAMGLASVEHVVHTTQEAGIDIALPATVLEVFRRGMKTGHASDSFTSLIEIFKNS 306 >3G0O-A nrPDB Length = 303 Score = 78.2 bits (191), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 71/285 (24%), Positives = 127/285 (44%), Gaps = 6/285 (2%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLS--KCDELVEHGA-SVCESPAEVIKKCK 58 VG +GLG MG + + L+ G + W L+ C L+ GA S E Sbjct: 9 HVGIVGLGSMGMGAARSCLRAGL--STWGADLNPQACANLLAEGACGAAASAREFAGVVD 66 Query: 59 YTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEG 118 + ++ + V+F + GV + G + ST+ + + +I A+T ++ Sbjct: 67 ALVILVVNAAQVRQVLFGEDGVAHLMKPGSAVMVSSTISSADAQEIAAALTALNLNMLDA 126 Query: 119 PVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQV-GNGAKMKLIVNMIM 177 PVSG A G++ ++A+G +A F P D + + + G G+ +K+I ++ Sbjct: 127 PVSGGAVKAAQGEMTVMASGSEAAFTRLKPVLDAVASNVYRISDTPGAGSTVKIIHQLLA 186 Query: 178 GSMMNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQ 237 G + A +E + LA ++G+ D + D++ A + MF+ + + Y P + Sbjct: 187 GVHIAAAAEAMALAARAGIPLDVMYDVVTHAAGNSWMFENRMQHVVDGDYTPRSAVDIFV 246 Query: 238 KDMRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIE 282 KD+ L +P+A+ A F A + G G D SAVI+ Sbjct: 247 KDLGLVADTAKALRFPLPLASTALNMFTSASNAGYGKEDDSAVIK 291 >3QHA-A nrPDB Length = 296 Score = 76.6 bits (187), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 76/275 (27%), Positives = 126/275 (45%), Gaps = 18/275 (6%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60 +++G++GLG MG M+ + + VTV++ + L E GA++ +S A+V Sbjct: 16 LKLGYIGLGNMGAPMATRMTEWPGGVTVYDIRIEAMTPLAEAGATLADSVADVAAADLIH 75 Query: 61 IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120 I +L D VV + G G ST+ T++++ + + V+ PV Sbjct: 76 ITVLDD-AQVREVVGELAG---HAKPGTVIAIHSTISDTTAVELARDLKARDIHIVDAPV 131 Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 180 SG A G+L + D+ ++E PAF + G+ G G +MKL NM+ + Sbjct: 132 SGGAAAAARGELATMVGADREVYERIKPAFKHWAAVVIHAGEPGAGTRMKLARNMLTFTS 191 Query: 181 MNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSY----PPAF---PL 233 A E + LA+ +GL L ++ T+ + G G M + + P F P Sbjct: 192 YAAACEAMKLAEAAGLDLQALGRVVR---HTDALTGGPGAIMVRDNMKDLEPDNFLYQPF 248 Query: 234 KHQ----QKDMRLALALGDENAVSMPVAAAANEAF 264 H +KD+ LALALG+ +V +P+A A E Sbjct: 249 LHTRGLGEKDLSLALALGEAVSVDLPLARLAYEGL 283 >4OQZ-A nrPDB Length = 289 Score = 73.9 bits (180), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 71/294 (24%), Positives = 131/294 (44%), Gaps = 23/294 (7%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62 V +GLG MG+AM+ L G++VT+WNRT S+ D LV GA + +P + + + I Sbjct: 5 VTVIGLGPMGQAMAAAYLDRGYEVTLWNRTASRADALVARGAKLAATPEQALSANELVIL 64 Query: 63 MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSG 122 L D A V+ +G E+ G+ +++S+ E + + GG + G V Sbjct: 65 SLIDYDAMYGVL--EGA--EEAVAGRVLVNLSSDTPEKARAAARRVAELGGTHLTGGVLS 120 Query: 123 SKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIM-GSMM 181 + +G +A +++ A +V+ ++ Y G+ A + +NM++ M Sbjct: 121 PPPGIGSPDMSTFYSGPRAAYDQHRAALEVITGKTDYRGEDPGLAALMYQLNMVVFWPAM 180 Query: 182 NAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDM- 240 ++ + + LAD GL++ D+ + F G G ++ Y + D+ Sbjct: 181 LSYWQAVALADAHGLTA------ADIAPYVSENFAGMGQFID--FYAARIDAGNHAGDVD 232 Query: 241 RLALALGD---------ENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVK 285 RL++ + ++ V A +AF + G G FS+VI+ +K Sbjct: 233 RLSMGVASMEHVVHTNADSGVDTAFPRAVLDAFHRGADAGFGADSFSSVIKLMK 286 >5OCM-A nrPDB Length = 291 Score = 72.8 bits (177), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 51/190 (26%), Positives = 90/190 (47%), Gaps = 5/190 (2%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61 +V LGLG+MG+A++ LK+G TVWNR+ K +L E GA + S + + + Sbjct: 5 DVTVLGLGLMGQALAGAFLKDGHATTVWNRSEGKAGQLAEQGAVLASSARDAAEASPLVV 64 Query: 62 AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121 +SD A +V+ G VL G+ +++++ +E + E +G +++G + Sbjct: 65 VCVSDHAAVRAVLDPLGDVL----AGRVLVNLTSGTSEQARATAEWAAERGITYLDGAIM 120 Query: 122 GSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLG-QVGNGAKMKLIVNMIMGSM 180 + +L +G +A +E P LG + YLG G + + + IM Sbjct: 121 AIPQVVGTADAFLLYSGPEAAYEAHEPTLRSLGAGTTYLGADHGLSSLYDVALLGIMWGT 180 Query: 181 MNAFSEGLVL 190 +N+F G L Sbjct: 181 LNSFLHGAAL 190 >3ZHB-A nrPDB Length = 309 Score = 72.8 bits (177), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 55/228 (24%), Positives = 102/228 (44%), Gaps = 5/228 (2%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62 V +GLG+MG+A++ L G TVWNRT +K + LV GA S AE + + Sbjct: 22 VTVIGLGLMGQALAGAFLGAGHPTTVWNRTAAKAEPLVARGAKSAGSVAEAVAASPLVVV 81 Query: 63 MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSG 122 +SD A +++ G Q G+ +++++ + + + G+G +++G + Sbjct: 82 CVSDYDAVHALLDPLDGTALQ---GRTLVNLTSGTSAQARERAAWADGRGADYLDGAILA 138 Query: 123 SKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMI-MGSMM 181 ++L +G ++ F+ A LG + YLG A + ++ M S++ Sbjct: 139 GPAAIGTADAVVLLSGPRSAFDPHASALGGLGAGTTYLGADHGLASLYDAAGLVMMWSIL 198 Query: 182 NAFSEGLVLADKSGLSSDTLLDILDLGAMT-NPMFKGKGPSMNKSSYP 228 N F +G L +G+ + T + G T G ++ +YP Sbjct: 199 NGFLQGAALLGTAGVDATTFAPFITQGIGTVADWLPGYARQIDDGAYP 246 >5U5G-A nrPDB Length = 295 Score = 67.8 bits (164), Expect = 6e-12, Method: Compositional matrix adjust. Identities = 58/221 (26%), Positives = 99/221 (44%), Gaps = 12/221 (5%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCK--YT 60 VGF+GLG MG+A+ LL + V V NR+ K D+L+ GA + + + + Sbjct: 5 VGFIGLGRMGQAICRRLLASQMPVHVHNRSREKADDLIRQGAVWAPDIVALTRAARVLFV 64 Query: 61 IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120 S+ D+G +L + G +D+ST+ ET+ ++ A +G ++E PV Sbjct: 65 CTAGSEAVQDFYHAPDRG-LLACLEVGDIVVDLSTIAPETAEGLHAAFAQQGADYIECPV 123 Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 180 SG + A G L + +G + P +V Y+ + G ++K+ Sbjct: 124 SGGVEGALAGILSAIVSGRPEAYGLIRPLLEVFCATVTYVPEPGKAQRLKI--------- 174 Query: 181 MNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPS 221 +N +E + LA + S L LDL +M + +G S Sbjct: 175 LNNLAESINLAGAIEVISQGLSQGLDLKSMADVFTSCRGRS 215 >5G6R-A nrPDB Length = 295 Score = 66.2 bits (160), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 78/299 (26%), Positives = 127/299 (42%), Gaps = 22/299 (7%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61 +G GLG MG A++ L++G+K +VWNRT +K LVE GA + + +E + I Sbjct: 4 HIGIFGLGAMGTALAAKYLEHGYKTSVWNRTTAKAIPLVEQGAKLASTISEGVNANDLII 63 Query: 62 AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121 L + VV D Q K ++++ + K+ + +T G R++ G + Sbjct: 64 ICLLNN----QVVEDALRDALQTLPSKTIVNLTNGTPNQARKLADFVTSHGARYIHGGIM 119 Query: 122 GSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQ-VGNGAKMKLIVNMIMGSM 180 ++L +G+ +SI + L S YLG G+ + L + M + Sbjct: 120 AVPTMIGSPHAVLLYSGESLELFQSIESHLSLLGMSKYLGTDAGSASLHDLALLSGMYGL 179 Query: 181 MNAFSEGLVLADKSGLSSDT----LLDILD--LGAMTNPMFKGKGPSMNKSSYPPAFPLK 234 + F + L KSG + T LL +L L AMT G S+ K + + Sbjct: 180 FSGFLHAVALI-KSGQDTSTTATGLLPLLTPWLSAMT-----GYLSSIAKQIDDGDYATQ 233 Query: 235 HQQKDMRLA-----LALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVKFSR 288 M+LA + G+E VS + ++A G G D SA+IE K + Sbjct: 234 GSNLGMQLAGVENIIRAGEEQRVSSQMILPIKALIEQAVGEGHGGEDLSALIEYFKVGK 292 >4OQY-A nrPDB Length = 290 Score = 65.1 bits (157), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 72/286 (25%), Positives = 120/286 (41%), Gaps = 8/286 (2%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62 V +GLG MG+AM L NG +VTVWNRT SK + LV GA + + + + + + Sbjct: 6 VTVIGLGPMGQAMVNTFLDNGHEVTVWNRTASKAEALVARGAVLAPTVEDALSANELIVL 65 Query: 63 MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSG 122 L+D A +++ G L GK ++S+ + + + + G + + G V Sbjct: 66 SLTDYDAVYAILEPVTGSL----SGKVIANLSSDTPDKAREAAKWAAKHGAKHLTGGVQV 121 Query: 123 SKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNM-IMGSMM 181 + +G K +F+ VL + Y G+ A M M I + M Sbjct: 122 PPPLIGKPESSTYYSGPKDVFDAHEDTLKVL-TNADYRGEDAGLAAMYYQAQMTIFWTTM 180 Query: 182 NAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMF-KGKGPSMNKSSYPPAFP-LKHQQKD 239 ++ + L L +G+S+ LL + P F + ++ + YP L Sbjct: 181 LSYYQTLALGQANGVSAKELLPYATMMTSMMPHFLELYAQHVDSADYPGDVDRLAMGAAS 240 Query: 240 MRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVK 285 + L + VS + AA E FK G + FS++IE +K Sbjct: 241 VDHVLHTHQDAGVSTVLPAAVAEIFKAGMEKGFAENSFSSLIEVLK 286 >5A9T-A nrPDB Length = 290 Score = 63.5 bits (153), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 71/295 (24%), Positives = 125/295 (42%), Gaps = 26/295 (8%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60 + V GLG MG A++ LL G VTVWNR+ K LV GA + + + + Sbjct: 6 LPVTVAGLGPMGSALAAALLDRGHDVTVWNRSPGKAAPLVAKGARQADDIVDAVSASRLL 65 Query: 61 IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITG---KGGRFVE 117 + L+D A S + G + G+ +++ ++ T + NEA+ G +++ Sbjct: 66 VVCLADYDALYSAL----GPAREALRGRVVVNL---NSGTPKEANEALRWAERHGTGYLD 118 Query: 118 GPVSGSKKPAEDGQ--LIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNM 175 G + PA G + L +G +FEE LG +G A + ++ N Sbjct: 119 GAI--MVPPAMVGHPGSVFLYSGSAEVFEEYKETLAGLGDPV----HLGTEAGLAVLYNT 172 Query: 176 IMGSM----MNAFSEGLVLADKSGLSSDTLLDI-LD--LGAMTNPMFKGKGPSMNKSSYP 228 + SM MN F L +G+ + + +D L A+ + K + P++++ YP Sbjct: 173 ALLSMMYSSMNGFLHAAALVGSAGVPAAEFTKLAVDWFLPAVIGQIIKAEAPTIDEGVYP 232 Query: 229 -PAFPLKHQQKDMRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIE 282 A L+ ++ + E V + E +A + G G+ + +VIE Sbjct: 233 GDAGSLEMNVTTLKHIIGTSQEQGVDTEIPVRNKELLDRAVAAGFGESSYYSVIE 287 >3L6D-A nrPDB Length = 306 Score = 58.5 bits (140), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 72/301 (23%), Positives = 122/301 (40%), Gaps = 26/301 (8%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60 +V +GLG MG M+ LLK G +V +WNR+ K LV GA +CES + T Sbjct: 10 FDVSVIGLGAMGTIMAQVLLKQGKRVAIWNRSPGKAAALVAAGAHLCESVKAALSASPAT 69 Query: 61 IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120 I +L D A V+ G + + + +D +T + L + + GG +V+G + Sbjct: 70 IFVLLDNHATHEVLGMPG--VARALAHRTIVDYTTNAQDEGLALQGLVNQAGGHYVKGMI 127 Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 180 + + + GD+ FE+ + L + +L +++ + Sbjct: 128 VAYPRNVGHRESHSIHTGDREAFEQHRALLEGLAGHTVFLPW-DEALAFATVLHAHAFAA 186 Query: 181 MNAFSEGLVLADKSGL----SSDTLL--------DILDLGAMTNPMFKGKGPSMNKSSYP 228 M F E + D+ GL ++ LL D L+ KG + Sbjct: 187 MVTFFEAVGAGDRFGLPVSKTARLLLETSRFFVADALEEAVRRLETQDFKGDQARLDVHA 246 Query: 229 PAFPLKHQQKDMRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVKFSR 288 AF +A +L V PV A + ++A ++G GD D +A ++ F+R Sbjct: 247 DAFA--------HIAQSL-HAQGVWTPVFDAVCQVVQRAAAMGYGDQDIAATTKS--FAR 295 Query: 289 E 289 E Sbjct: 296 E 296 >2W8Z-A nrPDB Length = 470 Score = 50.4 bits (119), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 48/202 (23%), Positives = 86/202 (42%), Gaps = 17/202 (8%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEH-------GASVCESPAEVI 54 ++G +GL +MGK +++N+ G+ V V+NR K DE ++ G E + Sbjct: 6 QIGVIGLAVMGKNLALNIESKGYSVAVYNRLREKTDEFLQEAKGKNIVGTYSIEEFVNAL 65 Query: 55 KKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGR 114 +K + + M+ + + LE+ G ID + + + N+ + G Sbjct: 66 EKPRKILLMVKAGAPTDATIEQLKPHLEK---GDIVIDGGNTYFKDTQRRNKELAELGIH 122 Query: 115 FVEGPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKR------SFYLGQVGNGAK 168 F+ VSG ++ A G I+ G K E P F+ + + + Y+G G G Sbjct: 123 FIGTGVSGGEEGALKGPS-IMPGGQKEAHELVRPIFEAIAAKVDGEPCTTYIGPDGAGHY 181 Query: 169 MKLIVNMIMGSMMNAFSEGLVL 190 +K++ N I M +E L Sbjct: 182 VKMVHNGIEYGDMQLIAEAYFL 203 >6EOI-A nrPDB Length = 298 Score = 49.3 bits (116), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 34/116 (29%), Positives = 51/116 (43%), Gaps = 4/116 (3%) Query: 5 FLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIAML 64 GLG MG AM+ LK G TVWNRT +K + LVE GA + + I I L Sbjct: 12 IFGLGAMGTAMATQFLKQGHTPTVWNRTAAKANPLVEQGAHLAATIPAAIAASPLLIFCL 71 Query: 65 SDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120 D AA+ G GK ++++ + ++ + +G R+ G + Sbjct: 72 LD-NAAVEQTLAAG---PPSLAGKTILNLTNGTPSQARRLATLASARGARYFHGGI 123 >2ZYA-A nrPDB Length = 480 Score = 48.9 bits (115), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 49/211 (23%), Positives = 93/211 (44%), Gaps = 19/211 (9%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60 ++G +G+ +MG+ +++N+ G+ V+++NR+ K +E++ P +K+ Sbjct: 16 QQIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVIAENPGKKLVPYYTVKEF--- 72 Query: 61 IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMS--TVDA-----ETSLKINEAITGKGG 113 + L P L +V G I K Y+D +D + +++ N ++ +G Sbjct: 73 VESLETPRRILLMVKAGAGTDAAIDSLKPYLDKGDIIIDGGNTFFQDTIRRNRELSAEGF 132 Query: 114 RFVEGPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRS-------FYLGQVGNG 166 F+ VSG ++ A G I+ G K +E P + + Y+G G G Sbjct: 133 NFIGTGVSGGEEGALKGPS-IMPGGQKEAYELVAPILTKIAAVAEDGEPCVTYIGADGAG 191 Query: 167 AKMKLIVNMIMGSMMNAFSEGLVLADKSGLS 197 +K++ N I M +E L K GL+ Sbjct: 192 HYVKMVHNGIEYGDMQLIAEAYSLL-KGGLN 221 >2IZ1-A nrPDB Length = 474 Score = 45.1 bits (105), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 47/202 (23%), Positives = 87/202 (43%), Gaps = 19/202 (9%) Query: 4 GFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELV-EHG------ASVCESPAEVIKK 56 G +G+ +MGK +++N+ G+ V ++NRT SK +E+ EH E ++K Sbjct: 9 GVVGMAVMGKNLALNVESRGYTVAIYNRTTSKTEEVFKEHQDKNLVFTKTLEEFVGSLEK 68 Query: 57 CKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFV 116 + + M+ A + + +L + G ID +++ N + G F+ Sbjct: 69 PRRIMLMVQAGAATDATI---KSLLPLLDIGDILIDGGNTHFPDTMRRNAELADSGINFI 125 Query: 117 EGPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRS--------FYLGQVGNGAK 168 VSG +K A G ++ G K ++ P F+ + ++ Y+G G G Sbjct: 126 GTGVSGGEKGALLGP-SMMPGGQKEAYDLVAPIFEQIAAKAPQDGKPCVAYMGANGAGHY 184 Query: 169 MKLIVNMIMGSMMNAFSEGLVL 190 +K++ N I M +E L Sbjct: 185 VKMVHNGIEYGDMQLIAESYDL 206 >6FQY-A nrPDB Length = 468 Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 60/258 (23%), Positives = 108/258 (41%), Gaps = 54/258 (20%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDE---------LVEHGASVCESPAE 52 ++G +GL +MG+ +S+N+ GFK+ V+NRT + +E LV +G E Sbjct: 3 DIGLIGLAVMGQNLSLNISSKGFKIGVYNRTYERTEETMKRAKEENLVVYGYKTVEELIN 62 Query: 53 VIKKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYID---MSTVDAETSLKINE--- 106 +KK + I ++ A +V + +L+ +G ID +++E +K+ + Sbjct: 63 NLKKPRKVILLIK---AGPAVDENISNILKHFEKGDIIIDGGNEWYINSERRIKLCKEKD 119 Query: 107 ------AITG--KGGRFVEGPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSF 158 ++G G R+ + G K A D IL + + G Sbjct: 120 VEYLAMGVSGGEAGARYGCSFMPGGSKYAYDCVKEILEKCSAQVGNSPCVTYIGPGSSGN 179 Query: 159 YLGQVGNGAK---MKLIV-------------NMIMGSMMNAFSEGL-----------VLA 191 Y+ V NG + M+LI N + + N ++EG+ +LA Sbjct: 180 YVKMVHNGIEYGDMQLISESYVIMKHILKYDNQKLSEVFNKWNEGILNSYLIEITANILA 239 Query: 192 DKSGLSSDTLLD-ILDLG 208 K L+++ L+D ILD+ Sbjct: 240 KKDDLTNNYLVDMILDIA 257 >4E21-A nrPDB Length = 358 Score = 42.4 bits (98), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 56/241 (23%), Positives = 93/241 (38%), Gaps = 34/241 (14%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKK-CKY 59 M++G +GLG MG M L K G + V++ ++ L G + S E K K Sbjct: 23 MQIGMIGLGRMGADMVRRLRKGGHECVVYDLNVNAVQALEREGIAGARSIEEFCAKLVKP 82 Query: 60 TIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGP 119 + L P A + + + L + ID + ++ + + +G +V+ Sbjct: 83 RVVWLMVPAAVVDSMLQRMTPL--LAANDIVIDGGNSHYQDDIRRADQMRAQGITYVDVG 140 Query: 120 VSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLG-------------KRS-------FY 159 SG E G +++ G+K E P F L KR + Sbjct: 141 TSGGIFGLERGYCLMI-GGEKQAVERLDPVFRTLAPGIGAAPRTPGREKREGTAELGYLH 199 Query: 160 LGQVGNGAKMKLIVNMIMGSMMNAFSEGLVL-----ADKSGLSSDTLLDILDLGAMTNPM 214 G G G +K++ N I +M A++EGL + A K G +D + + NP Sbjct: 200 CGPSGAGHFVKMVHNGIEYGLMAAYAEGLNILHHANAGKEGQGADA-----ETAPLRNPD 254 Query: 215 F 215 F Sbjct: 255 F 255 >1PGJ-A nrPDB Length = 478 Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust. Identities = 47/216 (21%), Positives = 92/216 (42%), Gaps = 34/216 (15%) Query: 15 MSMNLLKNGFKVTVWNRTLSKCDELVEHGAS-----------VCESPAEVIKKCKYTIAM 63 +++N+ + GFKV V+NRT SK +E ++ AS E+ A +KK + + + Sbjct: 16 LALNIAEKGFKVAVFNRTYSKSEEFMKANASAPFAGNLKAFETMEAFAASLKKPRKALIL 75 Query: 64 LSDPCAA------LSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVE 117 + A L VF+KG +L +D + + + + G RF+ Sbjct: 76 VQAGAATDSTIEQLKKVFEKGDIL---------VDTGNAHFKDQGRRAQQLEAAGLRFLG 126 Query: 118 GPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRS-------FYLGQVGNGAKMK 170 +SG ++ A G G +++EE P + ++ G G G+ +K Sbjct: 127 MGISGGEEGARKGP-AFFPGGTLSVWEEIRPIVEAAAAKADDGRPCVTMNGSGGAGSCVK 185 Query: 171 LIVNMIMGSMMNAFSEGLVLADKSGLSSDTLLDILD 206 + N +++ + E + GL++D + +L+ Sbjct: 186 MYHNSGEYAILQIWGEVFDILRAMGLNNDEVAAVLE 221 >2P4Q-A nrPDB Length = 497 Score = 38.5 bits (88), Expect = 0.004, Method: Compositional matrix adjust. Identities = 16/43 (37%), Positives = 26/43 (60%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGA 44 + G +GL +MG+ + +N +GF V +NRT SK D + + A Sbjct: 12 DFGLIGLAVMGQNLILNAADHGFTVCAYNRTQSKVDHFLANEA 54 >4GWK-A nrPDB Length = 484 Score = 37.7 bits (86), Expect = 0.005, Method: Compositional matrix adjust. Identities = 15/43 (34%), Positives = 29/43 (67%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGA 44 ++ +GL +MG+ + +N+ +GF V +NRT+SK D+ + + A Sbjct: 6 DIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEA 48 >1PGO-A nrPDB Length = 482 Score = 37.7 bits (86), Expect = 0.006, Method: Compositional matrix adjust. Identities = 15/43 (34%), Positives = 29/43 (67%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGA 44 ++ +GL +MG+ + +N+ +GF V +NRT+SK D+ + + A Sbjct: 4 DIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEA 46 >2HK7-A nrPDB Length = 269 Score = 36.2 bits (82), Expect = 0.015, Method: Compositional matrix adjust. Identities = 23/61 (37%), Positives = 31/61 (50%), Gaps = 1/61 (1%) Query: 6 LGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEH-GASVCESPAEVIKKCKYTIAML 64 LG G +A+ L+K G KV +WNRT K +L + V SP EVI K + + Sbjct: 129 LGAGGASRAVIYALVKEGAKVFLWNRTKEKAIKLAQKFPLEVVNSPEEVIDKVQVIVNTT 188 Query: 65 S 65 S Sbjct: 189 S 189 >4YPO-A nrPDB Length = 333 Score = 34.7 bits (78), Expect = 0.056, Method: Compositional matrix adjust. Identities = 21/69 (30%), Positives = 33/69 (47%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61 +VG +G G G A S++L +G +V V + S+ VE ++PAEV K + Sbjct: 16 KVGVIGYGSQGHAHSLSLRDSGVQVRVGLKQGSRSRPKVEEQGLDVDTPAEVAKWADVVM 75 Query: 62 AMLSDPCAA 70 + D A Sbjct: 76 VLAPDTAQA 84 >4DGS-A nrPDB Length = 340 Score = 33.5 bits (75), Expect = 0.10, Method: Compositional matrix adjust. Identities = 18/57 (31%), Positives = 27/57 (47%), Gaps = 1/57 (1%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNR-TLSKCDELVEHGASVCESPAEVIKKC 57 +G LGLG +G+A++ G V WNR TLS D + ++V+ C Sbjct: 173 RIGVLGLGQIGRALASRAEAFGMSVRYWNRSTLSGVDWIAHQSPVDLARDSDVLAVC 229 >6C6P-A nrPDB Length = 458 Score = 32.3 bits (72), Expect = 0.23, Method: Compositional matrix adjust. Identities = 16/39 (41%), Positives = 25/39 (64%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELV 40 EV +G G++G A++ L ++G KVTV R L + D +V Sbjct: 9 EVIIVGAGVLGSALAAVLSRDGRKVTVIERDLKEPDRIV 47 >2D0I-A nrPDB Length = 333 Score = 32.0 bits (71), Expect = 0.30, Method: Compositional matrix adjust. Identities = 13/29 (44%), Positives = 20/29 (68%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNR 31 VG LG+G +GKA++ L+ G K+ W+R Sbjct: 149 VGILGMGAIGKAIARRLIPFGVKLYYWSR 177 >4WEQ-A nrPDB Length = 341 Score = 31.2 bits (69), Expect = 0.51, Method: Compositional matrix adjust. Identities = 12/30 (40%), Positives = 20/30 (66%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRT 32 VG +G+G++G+ + L GFKV W+R+ Sbjct: 164 VGIMGMGVLGQDAARKLAAMGFKVIGWSRS 193 >2F1K-A nrPDB Length = 279 Score = 31.2 bits (69), Expect = 0.51, Method: Compositional matrix adjust. Identities = 13/41 (31%), Positives = 27/41 (65%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVE 41 M++G +GLG++G +++ +L + G + +R S C++ VE Sbjct: 1 MKIGVVGLGLIGASLAGDLRRRGHYLIGVSRQQSTCEKAVE 41 >6C55-A nrPDB Length = 340 Score = 31.2 bits (69), Expect = 0.58, Method: Compositional matrix adjust. Identities = 19/65 (29%), Positives = 30/65 (46%), Gaps = 1/65 (1%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61 ++ +G G G A + NL NG+ V + R D+ E G V AE +K+ + Sbjct: 19 KIAVVGYGSQGHAHAQNLKDNGYDVVIGIRPGRSFDKAKEDGFDVFPV-AEAVKQADVIM 77 Query: 62 AMLSD 66 +L D Sbjct: 78 VLLPD 82 >3PGJ-A nrPDB Length = 302 Score = 30.8 bits (68), Expect = 0.76, Method: Compositional matrix adjust. Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 9/74 (12%) Query: 26 VTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI-AMLSDPCAALS--------VVFD 76 +TV NRT +K ++L E A+ E A+ ++ K + +++ A+L V+F Sbjct: 174 ITVTNRTFAKAEQLAELVAAYGEVKAQAFEQLKQSYDVIINSTSASLDGELPAIDPVIFS 233 Query: 77 KGGVLEQICEGKGY 90 V + GKGY Sbjct: 234 SRSVCYDMMYGKGY 247 >1TXG-A nrPDB Length = 335 Score = 30.4 bits (67), Expect = 0.81, Method: Compositional matrix adjust. Identities = 14/29 (48%), Positives = 19/29 (65%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVW 29 M V LG G MG A+S+ L+ NG +V +W Sbjct: 1 MIVSILGAGAMGSALSVPLVDNGNEVRIW 29 >5TSD-A nrPDB Length = 322 Score = 29.6 bits (65), Expect = 1.7, Method: Compositional matrix adjust. Identities = 14/30 (46%), Positives = 18/30 (60%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRT 32 VG +GLGI+G+ L GF V W+RT Sbjct: 145 VGVMGLGILGQDAVAKLKVMGFNVIGWSRT 174 >3K96-A nrPDB Length = 356 Score = 28.9 bits (63), Expect = 2.5, Method: Compositional matrix adjust. Identities = 13/43 (30%), Positives = 22/43 (51%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGAS 45 + LG G G A+++ L + G KV +W+ DE+ G + Sbjct: 32 IAILGAGSWGTALALVLARKGQKVRLWSYESDHVDEMQAEGVN 74 >4N18-A nrPDB Length = 332 Score = 28.9 bits (63), Expect = 3.0, Method: Compositional matrix adjust. Identities = 10/32 (31%), Positives = 21/32 (65%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRT 32 +G +GLG +G ++ L + G++V+ W+R+ Sbjct: 157 FHIGIMGLGEIGGYIADQLARLGYRVSGWSRS 188 >1BG6-A nrPDB Length = 359 Score = 28.5 bits (62), Expect = 3.6, Method: Compositional matrix adjust. Identities = 15/45 (33%), Positives = 21/45 (46%) Query: 6 LGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESP 50 LGLG G A + L G V W+ + E+ + GA + E P Sbjct: 10 LGLGNGGHAFAAYLALKGQSVLAWDIDAQRIKEIQDRGAIIAEGP 54 >1T0K-B nrPDB Length = 105 Score = 28.5 bits (62), Expect = 3.7, Method: Compositional matrix adjust. Identities = 21/74 (28%), Positives = 35/74 (47%), Gaps = 1/74 (1%) Query: 93 MSTVDAETSLKINEAITGKGGRFVEGPVSGSKKPAE-DGQLIILAAGDKALFEESIPAFD 151 M+ V ++ S+ A+ K G++ G S K + +LII+AA L + + + Sbjct: 1 MAPVKSQESINQKLALVIKSGKYTLGYKSTVKSLRQGKSKLIIIAANTPVLRKSELEYYA 60 Query: 152 VLGKRSFYLGQVGN 165 +L K Y Q GN Sbjct: 61 MLSKTKVYYFQGGN 74 >5JOY-A nrPDB Length = 516 Score = 28.1 bits (61), Expect = 4.1, Method: Compositional matrix adjust. Identities = 15/51 (29%), Positives = 26/51 (50%), Gaps = 4/51 (7%) Query: 72 SVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEA---ITGKGGRFVEGP 119 S+ F+ G + GYI++ +D T +++ + G GGR+ EGP Sbjct: 132 SLYFEDGKCF-MVSNPDGYINLCEIDPMTGKQLSSSKRIWNGTGGRYAEGP 181 >6IUM-B nrPDB Length = 701 Score = 27.7 bits (60), Expect = 5.6, Method: Compositional matrix adjust. Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAE-VIKKCKYT 60 +V +G G MG +SMN L G VT+ L E ++ G + E KK K T Sbjct: 294 KVAVIGAGTMGGGISMNFLNAGIPVTI----LETKQEALDRGVGIIRKNYENSAKKGKLT 349 >3GGO-A nrPDB Length = 314 Score = 27.7 bits (60), Expect = 6.2, Method: Compositional matrix adjust. Identities = 36/146 (24%), Positives = 64/146 (43%), Gaps = 17/146 (11%) Query: 6 LGLGIMGKAMSMNLLKNGFKVTVWN-----RTLSKCDELVEHGASVCESPAEVIKKCKYT 60 +G+G MG + + +L ++GFK ++ ++SK +L + E + K ++ Sbjct: 39 VGVGFMGGSFAKSLRRSGFKGKIYGYDINPESISKAVDL----GIIDEGTTSIAKVEDFS 94 Query: 61 --IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEG 118 MLS P + K + + E D +V + + E I GK RFV G Sbjct: 95 PDFVMLSSPVRTFREIAKKLSYI--LSEDATVTDQGSVKGKLVYDL-ENILGK--RFVGG 149 Query: 119 -PVSGSKKPAEDGQLIILAAGDKALF 143 P++G++K + L L G K + Sbjct: 150 HPIAGTEKSGVEYSLDNLYEGKKVIL 175 >2G5C-A nrPDB Length = 281 Score = 27.7 bits (60), Expect = 6.6, Method: Compositional matrix adjust. Identities = 36/146 (24%), Positives = 64/146 (43%), Gaps = 17/146 (11%) Query: 6 LGLGIMGKAMSMNLLKNGFKVTVWN-----RTLSKCDELVEHGASVCESPAEVIKKCKYT 60 +G+G MG + + +L ++GFK ++ ++SK +L + E + K ++ Sbjct: 7 VGVGFMGGSFAKSLRRSGFKGKIYGYDINPESISKAVDL----GIIDEGTTSIAKVEDFS 62 Query: 61 --IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEG 118 MLS P + K + + E D +V + + E I GK RFV G Sbjct: 63 PDFVMLSSPVRTFREIAKKLSYI--LSEDATVTDQGSVKGKLVYDL-ENILGK--RFVGG 117 Query: 119 -PVSGSKKPAEDGQLIILAAGDKALF 143 P++G++K + L L G K + Sbjct: 118 HPIAGTEKSGVEYSLDNLYEGKKVIL 143 >4XA8-A nrPDB Length = 320 Score = 26.9 bits (58), Expect = 9.2, Method: Compositional matrix adjust. Identities = 15/32 (46%), Positives = 22/32 (68%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRT 32 + VG LGLG +G A ++ L ++GF V W+RT Sbjct: 145 IRVGVLGLGDLGAAAALELARHGFDVRGWSRT 176 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3DOJ-A nrPDB 342 8e-95 2UYY-A nrPDB 301 3e-82 3PEF-A nrPDB 298 1e-81 3PDU-A nrPDB 288 1e-78 5XVH-A nrPDB 283 5e-77 1YB4-A nrPDB 282 1e-76 1VPD-A nrPDB 278 2e-75 5JE8-A nrPDB 272 1e-73 2GF2-A nrPDB 271 2e-73 3CKY-A nrPDB 269 1e-72 4D3F-A nrPDB 252 1e-67 4DLL-A nrPDB 250 7e-67 4GBJ-A nrPDB 241 2e-64 4OQY-A nrPDB 241 2e-64 2CVZ-A nrPDB 241 3e-64 5Y8M-A nrPDB 224 3e-59 3G0O-A nrPDB 221 3e-58 4OQZ-A nrPDB 219 1e-57 3Q3C-A nrPDB 218 2e-57 5U5G-A nrPDB 212 1e-55 5A9T-A nrPDB 211 4e-55 4D3S-A nrPDB 210 6e-55 3ZHB-A nrPDB 208 2e-54 2W8Z-A nrPDB 203 7e-53 5G6R-A nrPDB 201 2e-52 5OCM-A nrPDB 191 4e-49 3QHA-A nrPDB 191 4e-49 2IZ1-A nrPDB 189 2e-48 2ZYA-A nrPDB 186 1e-47 3L6D-A nrPDB 186 1e-47 6FQY-A nrPDB 169 1e-42 6EOI-A nrPDB 169 2e-42 4E21-A nrPDB 168 2e-42 1PGJ-A nrPDB 159 9e-40 Sequences not found previously or not previously below threshold: 1PGO-A nrPDB 146 8e-36 4GWK-A nrPDB 140 4e-34 2P4Q-A nrPDB 140 4e-34 4R16-A nrPDB 67 1e-11 2Y0D-A nrPDB 59 3e-09 2F1K-A nrPDB 56 2e-08 2D0I-A nrPDB 49 2e-06 4DGS-A nrPDB 49 2e-06 3OJO-A nrPDB 47 8e-06 4OM8-A nrPDB 47 9e-06 2WWR-A nrPDB 46 2e-05 5AOV-A nrPDB 46 2e-05 4YPO-A nrPDB 46 2e-05 1GPJ-A nrPDB 45 3e-05 3KBO-A nrPDB 45 3e-05 6HD1-C nrPDB 44 5e-05 4G2N-A nrPDB 44 7e-05 4N18-A nrPDB 44 8e-05 3TRI-A nrPDB 44 9e-05 5WHX-A nrPDB 44 9e-05 3GGO-A nrPDB 44 1e-04 2G5C-A nrPDB 44 1e-04 4KQW-A nrPDB 44 1e-04 6BII-A nrPDB 43 2e-04 1MV8-A nrPDB 42 2e-04 5UOG-A nrPDB 42 2e-04 3VTF-A nrPDB 42 2e-04 4EBF-A nrPDB 42 2e-04 2I99-A nrPDB 42 2e-04 4TSK-A nrPDB 42 3e-04 2HK7-A nrPDB 42 3e-04 1NP3-A nrPDB 42 4e-04 3MOG-A nrPDB 42 4e-04 6C55-A nrPDB 41 6e-04 2DLD-A nrPDB 41 7e-04 4XA8-A nrPDB 41 8e-04 1TXG-A nrPDB 40 8e-04 4WEQ-A nrPDB 40 8e-04 3JTM-A nrPDB 40 9e-04 5B37-A nrPDB 40 0.001 1BG6-A nrPDB 40 0.001 3DC2-A nrPDB 40 0.001 6G1M-A nrPDB 40 0.001 5Z1Z-A nrPDB 40 0.002 1YON-A nrPDB 39 0.002 5T57-A nrPDB 39 0.003 3G79-A nrPDB 39 0.003 5TSD-A nrPDB 39 0.003 1GDH-A nrPDB 38 0.004 1ZEJ-A nrPDB 38 0.005 4A7P-A nrPDB 38 0.005 5C5I-A nrPDB 38 0.005 2AHR-A nrPDB 38 0.005 1J49-A nrPDB 38 0.006 4ZGS-A nrPDB 38 0.006 4BVA-A nrPDB 38 0.006 6HRD-A nrPDB 37 0.007 5N2I-A nrPDB 37 0.008 4B3J-A nrPDB 37 0.008 1HL3-A nrPDB 37 0.009 5E4R-A nrPDB 37 0.010 2QYS-A nrPDB 37 0.010 1YQG-A nrPDB 37 0.011 2CUK-A nrPDB 37 0.013 1ZCJ-A nrPDB 37 0.013 3HDH-A nrPDB 37 0.013 6ABJ-A nrPDB 37 0.013 4XDZ-A nrPDB 37 0.014 4N7R-A nrPDB 36 0.015 1F14-A nrPDB 36 0.015 3ZWA-A nrPDB 36 0.016 2VHY-A nrPDB 36 0.020 4J90-A nrPDB 36 0.021 2RCY-A nrPDB 35 0.028 6IUM-B nrPDB 35 0.029 3K96-A nrPDB 35 0.032 3BA1-A nrPDB 35 0.033 1CER-O nrPDB 35 0.033 4MIE-A nrPDB 35 0.034 2EV9-A nrPDB 35 0.037 4DYD-A nrPDB 35 0.039 1QP8-A nrPDB 35 0.041 4ZCC-A nrPDB 35 0.042 2YQ5-A nrPDB 35 0.052 2HMT-A nrPDB 34 0.055 5BUT-A nrPDB 34 0.059 5VJ7-A nrPDB 34 0.064 5YEQ-A nrPDB 34 0.068 6IH4-A nrPDB 34 0.069 3KB6-A nrPDB 34 0.092 3I83-A nrPDB 34 0.093 6ACQ-A nrPDB 34 0.097 2RIR-A nrPDB 34 0.099 3KKJ-A nrPDB 34 0.11 5JFC-L nrPDB 34 0.12 4LSW-A nrPDB 33 0.13 4A5O-A nrPDB 33 0.14 3TWO-A nrPDB 33 0.15 3FR8-A nrPDB 33 0.18 4A6N-B nrPDB 33 0.21 1JAY-A nrPDB 33 0.21 2OME-A nrPDB 32 0.22 6NRP-A nrPDB 32 0.31 3LK7-A nrPDB 32 0.36 5OES-A nrPDB 32 0.37 2EGG-A nrPDB 32 0.38 4KUG-A nrPDB 32 0.39 4CUK-A nrPDB 32 0.42 1GEG-A nrPDB 32 0.44 1A5Z-A nrPDB 32 0.45 5Y77-A nrPDB 31 0.50 4PRK-A nrPDB 31 0.50 3WNV-A nrPDB 31 0.51 2EW2-A nrPDB 31 0.52 1NYT-A nrPDB 31 0.52 6C6P-A nrPDB 31 0.55 4FQ8-A nrPDB 31 0.57 3QY9-A nrPDB 31 0.62 4K28-A nrPDB 31 0.66 4HY3-A nrPDB 31 0.67 3GT0-A nrPDB 31 0.67 4FSH-A nrPDB 31 0.68 4OH1-A nrPDB 31 0.69 1VC2-A nrPDB 30 0.81 1XDW-A nrPDB 30 0.87 1PS9-A nrPDB 30 0.96 3PGJ-A nrPDB 30 1.0 3DDL-A nrPDB 30 1.1 5NMX-A nrPDB 30 1.2 5X6R-A nrPDB 30 1.2 1DOH-A nrPDB 30 1.2 2WTB-A nrPDB 30 1.2 3W8X-A nrPDB 30 1.4 2E18-A nrPDB 30 1.4 1BW9-B nrPDB 30 1.5 6APH-A nrPDB 30 1.5 3NT2-A nrPDB 30 1.6 3WFI-A nrPDB 30 1.7 1ZFN-A nrPDB 30 1.7 2EKL-A nrPDB 30 1.7 6ABI-A nrPDB 30 1.8 3UP5-A nrPDB 29 1.8 3KTD-A nrPDB 29 1.9 4PZE-A nrPDB 29 1.9 2TMD-A nrPDB 29 1.9 5BSH-A nrPDB 29 2.0 2BW0-A nrPDB 29 2.0 3J9R-A nrPDB 29 2.0 3K6J-A nrPDB 29 2.0 1HYH-A nrPDB 29 2.0 2CBN-A nrPDB 29 2.1 4OVI-A nrPDB 29 2.2 3L9X-A nrPDB 29 2.2 4YRY-B nrPDB 29 2.6 1E5Q-A nrPDB 29 2.7 5U9P-A nrPDB 29 3.2 3OSU-A nrPDB 29 3.4 2DBZ-A nrPDB 29 3.5 4J0E-A nrPDB 29 3.6 2PAJ-A nrPDB 29 3.6 2PB9-A nrPDB 29 3.8 6BMQ-A nrPDB 28 3.9 3ZV3-A nrPDB 28 4.0 5EVJ-A nrPDB 28 4.2 6IHE-A nrPDB 28 4.4 6J0Z-C nrPDB 28 4.8 1UB3-A nrPDB 28 5.0 2DZB-A nrPDB 28 5.3 3WYE-A nrPDB 28 5.5 1PJB-A nrPDB 28 5.6 5IOB-A nrPDB 28 5.9 3HWR-A nrPDB 28 5.9 2DC1-A nrPDB 28 6.3 4OMU-A nrPDB 28 6.7 5XGV-A nrPDB 27 6.9 1LSS-A nrPDB 27 7.0 5UAU-A nrPDB 27 7.4 2V3B-A nrPDB 27 7.4 5CJE-A nrPDB 27 8.3 2VDC-G nrPDB 27 8.6 2GRA-A nrPDB 27 8.6 4HB9-A nrPDB 27 9.0 4Y4N-A nrPDB 27 9.3 >3DOJ-A nrPDB Length = 310 Score = 342 bits (878), Expect = 8e-95, Method: Composition-based stats. Identities = 289/289 (100%), Positives = 289/289 (100%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT Sbjct: 22 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 81 Query: 61 IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120 IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV Sbjct: 82 IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 141 Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 180 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM Sbjct: 142 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 201 Query: 181 MNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDM 240 MNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDM Sbjct: 202 MNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDM 261 Query: 241 RLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVKFSRE 289 RLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVKFSRE Sbjct: 262 RLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVKFSRE 310 >2UYY-A nrPDB Length = 316 Score = 301 bits (770), Expect = 3e-82, Method: Composition-based stats. Identities = 140/283 (49%), Positives = 189/283 (66%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61 ++GFLGLG+MG + NLLK G VTVWNRT KCD ++ GA + +PAEV+ C T Sbjct: 32 KIGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKCDLFIQEGARLGRTPAEVVSTCDITF 91 Query: 62 AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121 A +SDP AA +V GVL+ I GK Y+DMSTVDA+T ++ + I +GGRF+E PVS Sbjct: 92 ACVSDPKAAKDLVLGPSGVLQGIRPGKCYVDMSTVDADTVTELAQVIVSRGGRFLEAPVS 151 Query: 122 GSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMM 181 G+++ + DG L+ILAAGD+ L+E+ F +GK SF+LG+VGN AKM LIVNM+ GS M Sbjct: 152 GNQQLSNDGMLVILAAGDRGLYEDCSSCFQAMGKTSFFLGEVGNAAKMMLIVNMVQGSFM 211 Query: 182 NAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDMR 241 +EGL LA +G S TLLDIL+ G + + K ++ + ++ P F LK+ QKD+R Sbjct: 212 ATIAEGLTLAQVTGQSQQTLLDILNQGQLASIFLDQKCQNILQGNFKPDFYLKYIQKDLR 271 Query: 242 LALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAV 284 LA+ALGD P+AAAANE +K+A++L D D SAV A Sbjct: 272 LAIALGDAVNHPTPMAAAANEVYKRAKALDQSDNDMSAVYRAY 314 >3PEF-A nrPDB Length = 287 Score = 298 bits (764), Expect = 1e-81, Method: Composition-based stats. Identities = 159/285 (55%), Positives = 205/285 (71%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60 + GF+GLGIMG AM+ NL+K G VT+WNR+ K +EL GA +P EV++ C T Sbjct: 2 QKFGFIGLGIMGSAMAKNLVKAGCSVTIWNRSPEKAEELAALGAERAATPCEVVESCPVT 61 Query: 61 IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120 AML+DP AA V F K GVLE I EG+GY+DMSTVD TS +I A+ KGGRF+E PV Sbjct: 62 FAMLADPAAAEEVCFGKHGVLEGIGEGRGYVDMSTVDPATSQRIGVAVVAKGGRFLEAPV 121 Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 180 SGSKKPAEDG LIILAAGD+ L++E++P F+ +GK+ +LG VG GA+MKL+VNM+MG M Sbjct: 122 SGSKKPAEDGTLIILAAGDRNLYDEAMPGFEKMGKKIIHLGDVGKGAEMKLVVNMVMGGM 181 Query: 181 MNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDM 240 M F EGL L +K+GL++D +LD++ GAM NPMF KG + ++ PAFPLKH QKD+ Sbjct: 182 MACFCEGLALGEKAGLATDAILDVIGAGAMANPMFALKGGLIRDRNFAPAFPLKHMQKDL 241 Query: 241 RLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVK 285 RLA+ALGD + +AAANE FK AR+ G GD DFSA+ + + Sbjct: 242 RLAVALGDRVGQPLVASAAANELFKGARAAGFGDEDFSAIFKTYE 286 >3PDU-A nrPDB Length = 287 Score = 288 bits (738), Expect = 1e-78, Method: Composition-based stats. Identities = 164/282 (58%), Positives = 198/282 (70%) Query: 4 GFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIAM 63 GFLGLGIMG M+ NL++ GF VTVWNR +KC LV GA SPAEV C TIAM Sbjct: 5 GFLGLGIMGGPMAANLVRAGFDVTVWNRNPAKCAPLVALGARQASSPAEVCAACDITIAM 64 Query: 64 LSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSGS 123 L+DP AA V F GVLE I G+GYIDMSTVD ETS I A+T +GGRF+E PVSG+ Sbjct: 65 LADPAAAREVCFGANGVLEGIGGGRGYIDMSTVDDETSTAIGAAVTARGGRFLEAPVSGT 124 Query: 124 KKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMMNA 183 KKPAEDG LIILAAGD++LF ++ PAF LGK+ +LG+VG GA+MKL+VNMIMG MM A Sbjct: 125 KKPAEDGTLIILAAGDQSLFTDAGPAFAALGKKCLHLGEVGQGARMKLVVNMIMGQMMTA 184 Query: 184 FSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDMRLA 243 EG+ L GL LL++LD GAM NPMFKGKG + +P +FPLKH QKD+RLA Sbjct: 185 LGEGMALGRNCGLDGGQLLEVLDAGAMANPMFKGKGQMLLSGEFPTSFPLKHMQKDLRLA 244 Query: 244 LALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVK 285 + LGD + AA ANE+FK+AR+ G D DF+AV ++ Sbjct: 245 VELGDRLGQPLHGAATANESFKRARAAGHADEDFAAVFRVLE 286 >5XVH-A nrPDB Length = 306 Score = 283 bits (725), Expect = 5e-77, Method: Composition-based stats. Identities = 99/280 (35%), Positives = 142/280 (50%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60 M VGF+GLGIMG M+ +LLK GF V+NRT K E G V ESPA++ K+ Sbjct: 21 MRVGFIGLGIMGGPMATHLLKAGFLAAVYNRTREKTKPFAEAGVYVAESPADLAKRVDVV 80 Query: 61 IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120 I M+SD V+F GV+E G +DMST + + K E + G F++ PV Sbjct: 81 IVMVSDAPDVEQVLFGPSGVVEGARPGLIVVDMSTNSPDWARKFAERLAQYGIEFLDAPV 140 Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 180 +G +K A +G L I+ G + LF +P F +G+ Y+G VG G MKL+ +++ Sbjct: 141 TGGQKGAIEGTLTIMVGGKEELFHRLLPIFKAMGRDIVYMGPVGYGQAMKLVNQVVVALN 200 Query: 181 MNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDM 240 A EGL LA GL D + ++L GA + + P + K P F +H +KD+ Sbjct: 201 TVAMVEGLKLAKALGLDMDKVAEVLTRGAARSGAIELYLPKLLKGDLSPGFKAEHLKKDL 260 Query: 241 RLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAV 280 L + V +P A A E ++K G G L A+ Sbjct: 261 GYVLEEARKRGVKLPGAELAYELYRKMVEDGAGSLGIHAL 300 >1YB4-A nrPDB Length = 295 Score = 282 bits (721), Expect = 1e-76, Method: Composition-based stats. Identities = 84/286 (29%), Positives = 144/286 (50%), Gaps = 1/286 (0%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60 M++GF+GLGIMG M++NL + G ++ V DEL+ GA E+ +V + Sbjct: 4 MKLGFIGLGIMGSPMAINLARAGHQLHVTTIGPV-ADELLSLGAVNVETARQVTEFADII 62 Query: 61 IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120 M+ D V+F + G + +GK +DMS++ + + + + G +++ PV Sbjct: 63 FIMVPDTPQVEDVLFGEHGCAKTSLQGKTIVDMSSISPIETKRFAQRVNEMGADYLDAPV 122 Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 180 SG + A +G L I+ G++ +F+ P FD+LGK +G G+G K+ +I+ Sbjct: 123 SGGEIGAREGTLSIMVGGEQKVFDRVKPLFDILGKNITLVGGNGDGQTCKVANQIIVALN 182 Query: 181 MNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDM 240 + A SE LV A K+G + L G ++ + + G M ++ P F + QKD+ Sbjct: 183 IEAVSEALVFASKAGADPVRVRQALMGGFASSRILEVHGERMINRTFEPGFKIALHQKDL 242 Query: 241 RLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVKF 286 LAL A+++P A E F + G LD SA+++A++ Sbjct: 243 NLALQSAKALALNLPNTATCQELFNTCAANGGSQLDHSAMVQALEL 288 >1VPD-A nrPDB Length = 299 Score = 278 bits (711), Expect = 2e-75, Method: Composition-based stats. Identities = 86/280 (30%), Positives = 140/280 (50%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60 M+VGF+GLGIMGK MS NLLK G+ + V +R +++ GA + + ++C Sbjct: 6 MKVGFIGLGIMGKPMSKNLLKAGYSLVVSDRNPEAIADVIAAGAETASTAKAIAEQCDVI 65 Query: 61 IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120 I ML + V + G++E G IDMS++ S +I++A+ KG ++ PV Sbjct: 66 ITMLPNSPHVKEVALGENGIIEGAKPGTVLIDMSSIAPLASREISDALKAKGVEMLDAPV 125 Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 180 SG + A DG L ++ GDKA+F++ + + G +G G KL +I+ Sbjct: 126 SGGEPKAIDGTLSVMVGGDKAIFDKYYDLMKAMAGSVVHTGDIGAGNVTKLANQVIVALN 185 Query: 181 MNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDM 240 + A SE L LA K+G++ D + + G + + K P + ++ P F + KD+ Sbjct: 186 IAAMSEALTLATKAGVNPDLVYQAIRGGLAGSTVLDAKAPMVMDRNFKPGFRIDLHIKDL 245 Query: 241 RLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAV 280 AL +P+ AA E + R+ G G+ D SA+ Sbjct: 246 ANALDTSHGVGAQLPLTAAVMEMMQALRADGHGNDDHSAL 285 >5JE8-A nrPDB Length = 302 Score = 272 bits (696), Expect = 1e-73, Method: Composition-based stats. Identities = 79/285 (27%), Positives = 140/285 (49%), Gaps = 2/285 (0%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61 ++GF+GLG MG MS NL+K+G+ V + + G + S +++ + C Sbjct: 9 KIGFIGLGNMGLPMSKNLVKSGYTVYGVDLNKEAEASFEKEGGIIGLSISKLAETCDVVF 68 Query: 62 AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121 L P A +V F G+ E +ID STV + + ++ EA K F+ PVS Sbjct: 69 TSLPSPRAVEAVYFGAEGLFENGHSNVVFIDTSTVSPQLNKQLEEAAKEKKVDFLAAPVS 128 Query: 122 GSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQ-VGNGAKMKLIVNMIMGSM 180 G AE+ L + G K ++E++ VLG F++ + + +G +KLI N+++G Sbjct: 129 GGVIGAENRTLTFMVGGSKDVYEKTESIMGVLGANIFHVSEQIDSGTTVKLINNLLIGFY 188 Query: 181 MNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFK-GKGPSMNKSSYPPAFPLKHQQKD 239 SE L LA K+ + D + DIL++ + +++ + +Y P F + +KD Sbjct: 189 TAGVSEALTLAKKNNMDLDKMFDILNVSYGQSRIYERNYKSFIAPENYEPGFTVNLLKKD 248 Query: 240 MRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAV 284 + A+ L E+ + +PV+ + +A G G+ D +A+ + V Sbjct: 249 LGFAVDLAKESELHLPVSEMLLNVYDEASQAGYGENDMAALYKKV 293 >2GF2-A nrPDB Length = 296 Score = 271 bits (694), Expect = 2e-73, Method: Composition-based stats. Identities = 77/292 (26%), Positives = 131/292 (44%), Gaps = 7/292 (2%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60 M VGF+GLG MG M+ NL+K+G+ + +++ C E + G V SPA+V +K Sbjct: 1 MPVGFIGLGNMGNPMAKNLMKHGYPLIIYDVFPDACKEFQDAGEQVVSSPADVAEKADRI 60 Query: 61 IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120 I ML A+ G+L+++ +G ID ST+D S ++ + + G F++ PV Sbjct: 61 ITMLPTSINAIEAYSGANGILKKVKKGSLLIDSSTIDPAVSKELAKEVEKMGAVFMDAPV 120 Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 180 SG A G L + G + F + +G Y G VG G K+ NM++ Sbjct: 121 SGGVGAARSGNLTFMVGGVEDEFAAAQELLGCMGSNVVYCGAVGTGQAAKICNNMLLAIS 180 Query: 181 MNAFSEGLVLADKSGLSSDTLLDILDLGAMT--NPMFKGKGPSMNKS-----SYPPAFPL 233 M +E + L + GL L IL++ + + P + +Y F Sbjct: 181 MIGTAEAMNLGIRLGLDPKLLAKILNMSSGRCWSSDTYNPVPGVMDGVPSANNYQGGFGT 240 Query: 234 KHQQKDMRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVK 285 KD+ LA + + + A++ ++ + G DFS+V + ++ Sbjct: 241 TLMAKDLGLAQDSATSTKSPILLGSLAHQIYRMMCAKGYSKKDFSSVFQFLR 292 >3CKY-A nrPDB Length = 301 Score = 269 bits (687), Expect = 1e-72, Method: Composition-based stats. Identities = 94/286 (32%), Positives = 152/286 (53%), Gaps = 1/286 (0%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60 +++GF+GLG MGK M++NLLK G V ++ + +V GA CE+ +V Sbjct: 5 IKIGFIGLGAMGKPMAINLLKEGVTVYAFDLMEANVAAVVAQGAQACENNQKVAAASDII 64 Query: 61 IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120 L + +V+ GGVL G +DMS+V ++LK+ + KG +V+ PV Sbjct: 65 FTSLPNAGIVETVMNGPGGVLSACKAGTVIVDMSSVSPSSTLKMAKVAAEKGIDYVDAPV 124 Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 180 SG K AE G L I+ +A+FE+ P V+GK +++G G G +K++ N+++G Sbjct: 125 SGGTKGAEAGTLTIMVGASEAVFEKIQPVLSVIGKDIYHVGDTGAGDAVKIVNNLLLGCN 184 Query: 181 MNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPS-MNKSSYPPAFPLKHQQKD 239 M + +E LVL K GL +T+ +I+ + + + K + + F + Q KD Sbjct: 185 MASLAEALVLGVKCGLKPETMQEIIGKSSGRSYAMEAKMEKFIMSGDFAGGFAMDLQHKD 244 Query: 240 MRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVK 285 + LAL G E V +P+ A A + F+ R++GLG D SAVI+ + Sbjct: 245 LGLALEAGKEGNVPLPMTAMATQIFEGGRAMGLGREDMSAVIKVWE 290 >4D3F-A nrPDB Length = 310 Score = 252 bits (643), Expect = 1e-67, Method: Composition-based stats. Identities = 70/288 (24%), Positives = 125/288 (43%), Gaps = 8/288 (2%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62 V +GLG MG+AM+ L+ G+ VTVWNRT SK D+LV GA + E + + I Sbjct: 24 VTVIGLGPMGQAMADVFLEYGYSVTVWNRTSSKADQLVAKGAIRVSTVNEALAANELVIL 83 Query: 63 MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSG 122 L+D S++ L GK +++S+ E + K + + +G R + G V Sbjct: 84 SLTDYNVMYSILEPVSENLF----GKVLVNLSSDTPEKARKAAKWLEDRGARHITGGVQV 139 Query: 123 SKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNM-IMGSMM 181 + +GD+ +FE +VL Y G+ A + + M I + M Sbjct: 140 PPSGIGKSESYTYYSGDRVVFEAHRETLEVLTSS-DYRGEDPGLAMLYYQIQMDIFWTAM 198 Query: 182 NAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMF-KGKGPSMNKSSYPPAF-PLKHQQKD 239 ++ L +A+ +G++++ L + P F + P +++ +P L Sbjct: 199 LSYLHALAIANANGITAEQFLPYASAMMSSLPKFVEFYTPRLDEGEHPGDVDRLAMGLAS 258 Query: 240 MRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVKFS 287 + + E + + + A E F++ G F+++IE K S Sbjct: 259 VEHVVHTTQEAGIDIALPATVLEVFRRGMKTGHASDSFTSLIEIFKNS 306 >4DLL-A nrPDB Length = 320 Score = 250 bits (637), Expect = 7e-67, Method: Composition-based stats. Identities = 82/280 (29%), Positives = 132/280 (47%), Gaps = 2/280 (0%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61 ++ FLG G MG M+ L + G+ + VWNRT ++ L GA++ E + + Sbjct: 33 KITFLGTGSMGLPMARRLCEAGYALQVWNRTPARAASLAALGATIHEQARAAARDADIVV 92 Query: 62 AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121 +ML + V+F + GV + G ++DM+++ + + G ++ PVS Sbjct: 93 SMLENGAVVQDVLFAQ-GVAAAMKPGSLFLDMASITPREARDHAARLGALGIAHLDTPVS 151 Query: 122 GSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMM 181 G AE G L+I+A G A FE S+P V G R+ ++G G+G KL MI+G + Sbjct: 152 GGTVGAEQGTLVIMAGGKPADFERSLPLLKVFG-RATHVGPHGSGQLTKLANQMIVGITI 210 Query: 182 NAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDMR 241 A +E L+ A K G + + + G + + + G M + + P L Q KDMR Sbjct: 211 GAVAEALLFATKGGADMAKVKEAITGGFADSRVLQLHGQRMVERDFAPRARLSIQLKDMR 270 Query: 242 LALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVI 281 ALA E P+ + + + GL DLD S + Sbjct: 271 NALATAQEIGFDAPITGLFEQLYAEGVEHGLTDLDQSGLF 310 >4GBJ-A nrPDB Length = 297 Score = 241 bits (616), Expect = 2e-64, Method: Composition-based stats. Identities = 71/281 (25%), Positives = 130/281 (46%), Gaps = 4/281 (1%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61 ++ FLGLG +G ++ LL+ G+++ VWNRT SK + L + GA+V E+ + I Sbjct: 7 KIAFLGLGNLGTPIAEILLEAGYELVVWNRTASKAEPLTKLGATVVENAIDAITPGGIVF 66 Query: 62 AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121 ++L+D A + + ++E++ + ++ MST+ ETS ++ + G +V P+ Sbjct: 67 SVLADDAAVEELFSME--LVEKLGKDGVHVSMSTISPETSRQLAQVHEWYGAHYVGAPIF 124 Query: 122 GSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLG-QVGNGAKMKLIVNMIMGSM 180 + I +G+ E P + K F G G +KL N ++ Sbjct: 125 ARPEAVRAKVGNICLSGNAGAKERIKPIVENFVKGVFDFGDDPGAANVIKLAGNFMIACS 184 Query: 181 MNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPP-AFPLKHQQKD 239 + E +A+K+G+S ++ ++L P+F+ G + ++Y P AF KD Sbjct: 185 LEMMGEAFTMAEKNGISRQSIYEMLTSTLFAAPIFQNYGKLVASNTYEPVAFRFPLGLKD 244 Query: 240 MRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAV 280 + L L + MP A F + G +LD+ A+ Sbjct: 245 INLTLQTASDVNAPMPFADIIRNRFISGLAKGRENLDWGAL 285 >4OQY-A nrPDB Length = 290 Score = 241 bits (615), Expect = 2e-64, Method: Composition-based stats. Identities = 72/288 (25%), Positives = 120/288 (41%), Gaps = 8/288 (2%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60 V +GLG MG+AM L NG +VTVWNRT SK + LV GA + + + + + Sbjct: 4 QSVTVIGLGPMGQAMVNTFLDNGHEVTVWNRTASKAEALVARGAVLAPTVEDALSANELI 63 Query: 61 IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120 + L+D A +++ G L GK ++S+ + + + + G + + G V Sbjct: 64 VLSLTDYDAVYAILEPVTGSL----SGKVIANLSSDTPDKAREAAKWAAKHGAKHLTGGV 119 Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNM-IMGS 179 + +G K +F+ VL + Y G+ A M M I + Sbjct: 120 QVPPPLIGKPESSTYYSGPKDVFDAHEDTLKVL-TNADYRGEDAGLAAMYYQAQMTIFWT 178 Query: 180 MMNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMF-KGKGPSMNKSSYPPAF-PLKHQQ 237 M ++ + L L +G+S+ LL + P F + ++ + YP L Sbjct: 179 TMLSYYQTLALGQANGVSAKELLPYATMMTSMMPHFLELYAQHVDSADYPGDVDRLAMGA 238 Query: 238 KDMRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVK 285 + L + VS + AA E FK G + FS++IE +K Sbjct: 239 ASVDHVLHTHQDAGVSTVLPAAVAEIFKAGMEKGFAENSFSSLIEVLK 286 >2CVZ-A nrPDB Length = 289 Score = 241 bits (615), Expect = 3e-64, Method: Composition-based stats. Identities = 72/285 (25%), Positives = 128/285 (44%), Gaps = 7/285 (2%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61 +V F+GLG MG M+ +L + F VWNRT K E S P E + + + Sbjct: 3 KVAFIGLGAMGYPMAGHLARR-FPTLVWNRTFEKALRHQEEFGSEA-VPLERVAEARVIF 60 Query: 62 AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121 L V + + EG ++D ++ + E S ++ E + KG +++ PVS Sbjct: 61 TCLPTTREVYEVAEA---LYPYLREGTYWVDATSGEPEASRRLAERLREKGVTYLDAPVS 117 Query: 122 GSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMM 181 G AE G L ++ G + E P F K+ ++G VG G +K I N ++ + Sbjct: 118 GGTSGAEAGTLTVMLGGPEEAVERVRP-FLAYAKKVVHVGPVGAGHAVKAINNALLAVNL 176 Query: 182 NAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPS-MNKSSYPPAFPLKHQQKDM 240 A EGL+ K G+S++ L++++ + + + P + ++P F L KD+ Sbjct: 177 WAAGEGLLALVKQGVSAEKALEVINASSGRSNATENLIPQRVLTRAFPKTFALGLLVKDL 236 Query: 241 RLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVK 285 +A+ + D P+ A E ++ A+ D D + ++ Sbjct: 237 GIAMGVLDGEKAPSPLLRLAREVYEMAKRELGPDADHVEALRLLE 281 >5Y8M-A nrPDB Length = 295 Score = 224 bits (571), Expect = 3e-59, Method: Composition-based stats. Identities = 78/290 (26%), Positives = 123/290 (42%), Gaps = 11/290 (3%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62 + FLGLG MG MS NL+ G V ++ + HG +V S E + + I Sbjct: 5 IAFLGLGNMGAPMSANLVGAGHVVRGFDPAPTAASGAAAHGVAVFRSAPEAVAEADVVIT 64 Query: 63 MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSG 122 ML D VL +ID ST+ + +++ G ++ PVSG Sbjct: 65 MLPTGEVVRRCYTD---VLAAARPATLFIDSSTISVTDAREVHALAESHGMLQLDAPVSG 121 Query: 123 SKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMMN 182 K A L + GD++ + P + + + + G G G K+ NM++ Sbjct: 122 GVKGAAAATLAFMVGGDESTLRRARPVLEPMAGKIIHCGAAGAGQAAKVCNNMVLAVQQI 181 Query: 183 AFSEGLVLADKSGLSSDTLLDILD------LGAMTNPMFKGKGP-SMNKSSYPPAFPLKH 235 A +E VLA+K GLS+ +L D++ TN G P S + + P F Sbjct: 182 AIAEAFVLAEKLGLSAQSLFDVITGATGNCWAVHTNCPVPGPVPTSPANNDFKPGFSTAL 241 Query: 236 QQKDMRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVK 285 KD+ LA+ + P+ + A + + K + DLDFSAVI ++ Sbjct: 242 MNKDLGLAMDAVAATGATAPLGSHAADIYAK-FAADHADLDFSAVIHTLR 290 >3G0O-A nrPDB Length = 303 Score = 221 bits (563), Expect = 3e-58, Method: Composition-based stats. Identities = 69/286 (24%), Positives = 124/286 (43%), Gaps = 2/286 (0%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGA-SVCESPAEVIKKCKY 59 VG +GLG MG + + L+ G + C L+ GA S E Sbjct: 8 FHVGIVGLGSMGMGAARSCLRAGLSTWGADLNPQACANLLAEGACGAAASAREFAGVVDA 67 Query: 60 TIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGP 119 + ++ + V+F + GV + G + ST+ + + +I A+T ++ P Sbjct: 68 LVILVVNAAQVRQVLFGEDGVAHLMKPGSAVMVSSTISSADAQEIAAALTALNLNMLDAP 127 Query: 120 VSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQ-VGNGAKMKLIVNMIMG 178 VSG A G++ ++A+G +A F P D + + + G G+ +K+I ++ G Sbjct: 128 VSGGAVKAAQGEMTVMASGSEAAFTRLKPVLDAVASNVYRISDTPGAGSTVKIIHQLLAG 187 Query: 179 SMMNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQK 238 + A +E + LA ++G+ D + D++ A + MF+ + + Y P + K Sbjct: 188 VHIAAAAEAMALAARAGIPLDVMYDVVTHAAGNSWMFENRMQHVVDGDYTPRSAVDIFVK 247 Query: 239 DMRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAV 284 D+ L +P+A+ A F A + G G D SAVI+ Sbjct: 248 DLGLVADTAKALRFPLPLASTALNMFTSASNAGYGKEDDSAVIKIF 293 >4OQZ-A nrPDB Length = 289 Score = 219 bits (558), Expect = 1e-57, Method: Composition-based stats. Identities = 65/288 (22%), Positives = 121/288 (42%), Gaps = 7/288 (2%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60 V +GLG MG+AM+ L G++VT+WNRT S+ D LV GA + +P + + + Sbjct: 3 QSVTVIGLGPMGQAMAAAYLDRGYEVTLWNRTASRADALVARGAKLAATPEQALSANELV 62 Query: 61 IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120 I L D A V+ E+ G+ +++S+ E + + GG + G V Sbjct: 63 ILSLIDYDAMYGVLEG----AEEAVAGRVLVNLSSDTPEKARAAARRVAELGGTHLTGGV 118 Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNM-IMGS 179 + +G +A +++ A +V+ ++ Y G+ A + +NM + Sbjct: 119 LSPPPGIGSPDMSTFYSGPRAAYDQHRAALEVITGKTDYRGEDPGLAALMYQLNMVVFWP 178 Query: 180 MMNAFSEGLVLADKSGLSSDTLLDILDLG-AMTNPMFKGKGPSMNKSSYPPAF-PLKHQQ 237 M ++ + + LAD GL++ + + A ++ ++ L Sbjct: 179 AMLSYWQAVALADAHGLTAADIAPYVSENFAGMGQFIDFYAARIDAGNHAGDVDRLSMGV 238 Query: 238 KDMRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVK 285 M + ++ V A +AF + G G FS+VI+ +K Sbjct: 239 ASMEHVVHTNADSGVDTAFPRAVLDAFHRGADAGFGADSFSSVIKLMK 286 >3Q3C-A nrPDB Length = 299 Score = 218 bits (556), Expect = 2e-57, Method: Composition-based stats. Identities = 78/290 (26%), Positives = 130/290 (44%), Gaps = 7/290 (2%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61 ++ F+GLG MG M+ NLLK G+ + V++ S D LV GAS S + ++ I Sbjct: 4 QIAFIGLGHMGAPMATNLLKAGYLLNVFDLVQSAVDGLVAAGASAARSARDAVQGADVVI 63 Query: 62 AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121 +ML + D G+L I G ++ ST+ ++ KI+ A +G ++ PVS Sbjct: 64 SMLPASQHVEGLYLDDDGLLAHIAPGTLVLECSTIAPTSARKIHAAARERGLAMLDAPVS 123 Query: 122 GSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMM 181 G A G L + GD E++ P F+ +G+ F+ G G G K+ N ++ +M Sbjct: 124 GGTAGAAAGTLTFMVGGDAEALEKARPLFEAMGRNIFHAGPDGAGQVAKVCNNQLLAVLM 183 Query: 182 NAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGP-------SMNKSSYPPAFPLK 234 +E + L +GL + L +I+ + N + P + Y F + Sbjct: 184 IGTAEAMALGVANGLEAKVLAEIMRRSSGGNWALEVYNPWPGVMENAPASRDYSGGFMAQ 243 Query: 235 HQQKDMRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAV 284 KD+ LA +A S P+ + A ++ G + DFS V + Sbjct: 244 LMAKDLGLAQEAAQASASSTPMGSLALSLYRLLLKQGYAERDFSVVQKLF 293 >5U5G-A nrPDB Length = 295 Score = 212 bits (540), Expect = 1e-55, Method: Composition-based stats. Identities = 61/287 (21%), Positives = 108/287 (37%), Gaps = 2/287 (0%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62 VGF+GLG MG+A+ LL + V V NR+ K D+L+ GA + + + Sbjct: 5 VGFIGLGRMGQAICRRLLASQMPVHVHNRSREKADDLIRQGAVWAPDIVALTRAARVLFV 64 Query: 63 MLSDPCAALSVVFDKG-GVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121 + A G+L + G +D+ST+ ET+ ++ A +G ++E PVS Sbjct: 65 CTAGSEAVQDFYHAPDRGLLACLEVGDIVVDLSTIAPETAEGLHAAFAQQGADYIECPVS 124 Query: 122 GSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMM 181 G + A G L + +G + P +V Y+ + G ++K++ N+ + Sbjct: 125 GGVEGALAGILSAIVSGRPEAYGLIRPLLEVFCATVTYVPEPGKAQRLKILNNLAESINL 184 Query: 182 NAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDMR 241 E + GL ++ D+ + L + KD+ Sbjct: 185 AGAIEVISQGLSQGLDLKSMADVFTSCRGRSAYMDVALGYALSGGASSNVSLGVRCKDLE 244 Query: 242 LALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVKFSR 288 LA S P + A F R + D + ++ Sbjct: 245 LARRRL-PQDQSYPFSTLAMTTFDTVRQACGEESDQCQYFSVLSHNK 290 >5A9T-A nrPDB Length = 290 Score = 211 bits (536), Expect = 4e-55, Method: Composition-based stats. Identities = 60/289 (20%), Positives = 113/289 (39%), Gaps = 8/289 (2%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60 + V GLG MG A++ LL G VTVWNR+ K LV GA + + + + Sbjct: 6 LPVTVAGLGPMGSALAAALLDRGHDVTVWNRSPGKAAPLVAKGARQADDIVDAVSASRLL 65 Query: 61 IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120 + L+D A S + G + G+ +++++ + + + G +++G + Sbjct: 66 VVCLADYDALYSAL----GPAREALRGRVVVNLNSGTPKEANEALRWAERHGTGYLDGAI 121 Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 180 + L +G +FEE LG + G + +M S Sbjct: 122 MVPPAMVGHPGSVFLYSGSAEVFEEYKETLAGLGDPVHLGTEAGLAVLYNTALLSMMYSS 181 Query: 181 MNAFSEGLVLADKSGLSSDTLLDILD---LGAMTNPMFKGKGPSMNKSSYPPA-FPLKHQ 236 MN F L +G+ + + L A+ + K + P++++ YP L+ Sbjct: 182 MNGFLHAAALVGSAGVPAAEFTKLAVDWFLPAVIGQIIKAEAPTIDEGVYPGDAGSLEMN 241 Query: 237 QKDMRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVK 285 ++ + E V + E +A + G G+ + +VIE + Sbjct: 242 VTTLKHIIGTSQEQGVDTEIPVRNKELLDRAVAAGFGESSYYSVIELWR 290 >4D3S-A nrPDB Length = 293 Score = 210 bits (534), Expect = 6e-55, Method: Composition-based stats. Identities = 65/284 (22%), Positives = 117/284 (41%), Gaps = 5/284 (1%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61 V +GLG MG+AM+ LL+ G+++TVWNRT +K + L E GA+V +SPAE ++ + Sbjct: 10 PVTLIGLGPMGQAMAGALLEAGYELTVWNRTKAKAEALAERGAAVADSPAEALRAGGPVL 69 Query: 62 AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121 L++ V+ L +G+ +++ + S G G R+V G V Sbjct: 70 LSLTEHAVMYRVLEGAESDL----KGRTILNLGSDTPAASRAAAAWAEGHGARYVTGGVM 125 Query: 122 GSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMM 181 + +GD+A FEE+ +VL F G I+ + + M Sbjct: 126 SPAPGIGSSSVFSFYSGDRAAFEENKALLEVLTATDFRGEDPGLAQVYYQILLDLFWTTM 185 Query: 182 NAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAF-PLKHQQKDM 240 + L +A G+ T+ L G F+G ++ + +P + M Sbjct: 186 TGYLHALAVARAEGVPVGTITPYLIEGNDMAMFFEGTSAAVAEGRFPGDEDRISMDAASM 245 Query: 241 RLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAV 284 + + V + A F++ G + F+ ++ + Sbjct: 246 EHVVQTSRDAGVDTALPEAVLSLFRRGLDAGFAESSFARLVTLM 289 >3ZHB-A nrPDB Length = 309 Score = 208 bits (529), Expect = 2e-54, Method: Composition-based stats. Identities = 62/287 (21%), Positives = 120/287 (41%), Gaps = 6/287 (2%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61 V +GLG+MG+A++ L G TVWNRT +K + LV GA S AE + + Sbjct: 21 PVTVIGLGLMGQALAGAFLGAGHPTTVWNRTAAKAEPLVARGAKSAGSVAEAVAASPLVV 80 Query: 62 AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121 +SD A +++ G +G+ +++++ + + + G+G +++G + Sbjct: 81 VCVSDYDAVHALLDPLDGT---ALQGRTLVNLTSGTSAQARERAAWADGRGADYLDGAIL 137 Query: 122 GSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLG-QVGNGAKMKLIVNMIMGSM 180 ++L +G ++ F+ A LG + YLG G + ++M S+ Sbjct: 138 AGPAAIGTADAVVLLSGPRSAFDPHASALGGLGAGTTYLGADHGLASLYDAAGLVMMWSI 197 Query: 181 MNAFSEGLVLADKSGLSSDTLLDILDLGAMT-NPMFKGKGPSMNKSSYP-PAFPLKHQQK 238 +N F +G L +G+ + T + G T G ++ +YP + Sbjct: 198 LNGFLQGAALLGTAGVDATTFAPFITQGIGTVADWLPGYARQIDDGAYPADDAAIDTHLA 257 Query: 239 DMRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVK 285 M + + V+ + +A + G G + A+IE + Sbjct: 258 TMEHLIHESEFLGVNAELPRFIKALADRAVADGHGGSGYPALIEQFR 304 >2W8Z-A nrPDB Length = 470 Score = 203 bits (516), Expect = 7e-53, Method: Composition-based stats. Identities = 58/294 (19%), Positives = 109/294 (37%), Gaps = 29/294 (9%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEH-------GASVCESPAEVI 54 ++G +GL +MGK +++N+ G+ V V+NR K DE ++ G E + Sbjct: 6 QIGVIGLAVMGKNLALNIESKGYSVAVYNRLREKTDEFLQEAKGKNIVGTYSIEEFVNAL 65 Query: 55 KKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGR 114 +K + + M+ + + + +G ID + + + N+ + G Sbjct: 66 EKPRKILLMVKAGAPTDATIEQLK---PHLEKGDIVIDGGNTYFKDTQRRNKELAELGIH 122 Query: 115 FVEGPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRS------FYLGQVGNGAK 168 F+ VSG ++ A G I+ G K E P F+ + + Y+G G G Sbjct: 123 FIGTGVSGGEEGALKGP-SIMPGGQKEAHELVRPIFEAIAAKVDGEPCTTYIGPDGAGHY 181 Query: 169 MKLIVNMIMGSMMNAFSEGLVLAD-KSGLSSDTLLDIL---DLGAMTNPMFKGKGPSMNK 224 +K++ N I M +E L G+ + L ++ + G + + + + K Sbjct: 182 VKMVHNGIEYGDMQLIAEAYFLLKHVLGMDAAELHEVFADWNKGELNSYLIEITADIFTK 241 Query: 225 SSYPPAFPLKHQQKDMRLALALGD-------ENAVSMP-VAAAANEAFKKARSL 270 PL D G + V +P + + F A Sbjct: 242 IDEETGKPLVDVILDKAGQKGTGKWTSQNALDLGVPLPIITESVFARFLSAMKD 295 >5G6R-A nrPDB Length = 295 Score = 201 bits (512), Expect = 2e-52, Method: Composition-based stats. Identities = 69/294 (23%), Positives = 119/294 (40%), Gaps = 12/294 (4%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61 +G GLG MG A++ L++G+K +VWNRT +K LVE GA + + +E + I Sbjct: 4 HIGIFGLGAMGTALAAKYLEHGYKTSVWNRTTAKAIPLVEQGAKLASTISEGVNANDLII 63 Query: 62 AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121 L + + D L K ++++ + K+ + +T G R++ G + Sbjct: 64 ICLLNNQVVEDALRDALQTL----PSKTIVNLTNGTPNQARKLADFVTSHGARYIHGGIM 119 Query: 122 GSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLG-QVGNGAKMKLIVNMIMGSM 180 ++L +G+ +SI + L S YLG G+ + L + M + Sbjct: 120 AVPTMIGSPHAVLLYSGESLELFQSIESHLSLLGMSKYLGTDAGSASLHDLALLSGMYGL 179 Query: 181 MNAFSEGLVLADKSGLSSDT----LLDILD-LGAMTNPMFKGKGPSMNKSSYPP-AFPLK 234 + F + L KSG + T LL +L + ++ Y L Sbjct: 180 FSGFLHAVALI-KSGQDTSTTATGLLPLLTPWLSAMTGYLSSIAKQIDDGDYATQGSNLG 238 Query: 235 HQQKDMRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVKFSR 288 Q + + G+E VS + ++A G G D SA+IE K + Sbjct: 239 MQLAGVENIIRAGEEQRVSSQMILPIKALIEQAVGEGHGGEDLSALIEYFKVGK 292 >5OCM-A nrPDB Length = 291 Score = 191 bits (484), Expect = 4e-49, Method: Composition-based stats. Identities = 61/287 (21%), Positives = 121/287 (42%), Gaps = 7/287 (2%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61 +V LGLG+MG+A++ LK+G TVWNR+ K +L E GA + S + + + Sbjct: 5 DVTVLGLGLMGQALAGAFLKDGHATTVWNRSEGKAGQLAEQGAVLASSARDAAEASPLVV 64 Query: 62 AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121 +SD A +V+ G VL G+ +++++ +E + E +G +++G + Sbjct: 65 VCVSDHAAVRAVLDPLGDVLA----GRVLVNLTSGTSEQARATAEWAAERGITYLDGAIM 120 Query: 122 GSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMK-LIVNMIMGSM 180 + +L +G +A +E P LG + YLG + + + + IM Sbjct: 121 AIPQVVGTADAFLLYSGPEAAYEAHEPTLRSLGAGTTYLGADHGLSSLYDVALLGIMWGT 180 Query: 181 MNAFSEGLVLADKSGLSSDTLLDILD-LGAMTNPMFKGKGPSMNKSSYPP-AFPLKHQQK 238 +N+F G L + + + T + +++ +YP + Sbjct: 181 LNSFLHGAALLGTAKVEATTFAPFANRWIEAVTGFVSAYAGQVDQGAYPALDATIDTHVA 240 Query: 239 DMRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVK 285 + + + V+ + +A + G G L ++A+IE + Sbjct: 241 TVDHLIHESEAAGVNTELPRLVRTLADRALAGGQGGLGYAAMIEQFR 287 >3QHA-A nrPDB Length = 296 Score = 191 bits (484), Expect = 4e-49, Method: Composition-based stats. Identities = 74/287 (25%), Positives = 127/287 (44%), Gaps = 18/287 (6%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60 +++G++GLG MG M+ + + VTV++ + L E GA++ +S A+V Sbjct: 16 LKLGYIGLGNMGAPMATRMTEWPGGVTVYDIRIEAMTPLAEAGATLADSVADVAAADLIH 75 Query: 61 IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120 I +L D VV + G G ST+ T++++ + + V+ PV Sbjct: 76 ITVLDD-AQVREVVGELAG---HAKPGTVIAIHSTISDTTAVELARDLKARDIHIVDAPV 131 Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 180 SG A G+L + D+ ++E PAF + G+ G G +MKL NM+ + Sbjct: 132 SGGAAAAARGELATMVGADREVYERIKPAFKHWAAVVIHAGEPGAGTRMKLARNMLTFTS 191 Query: 181 MNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSY----PPAF----- 231 A E + LA+ +GL L ++ T+ + G G M + + P F Sbjct: 192 YAAACEAMKLAEAAGLDLQALGRVVR---HTDALTGGPGAIMVRDNMKDLEPDNFLYQPF 248 Query: 232 --PLKHQQKDMRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLD 276 +KD+ LALALG+ +V +P+A A E + + + Sbjct: 249 LHTRGLGEKDLSLALALGEAVSVDLPLARLAYEGLAAGLGVPHKEKE 295 >2IZ1-A nrPDB Length = 474 Score = 189 bits (479), Expect = 2e-48, Method: Composition-based stats. Identities = 53/279 (18%), Positives = 109/279 (39%), Gaps = 30/279 (10%) Query: 4 GFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEH-------GASVCESPAEVIKK 56 G +G+ +MGK +++N+ G+ V ++NRT SK +E+ + E ++K Sbjct: 9 GVVGMAVMGKNLALNVESRGYTVAIYNRTTSKTEEVFKEHQDKNLVFTKTLEEFVGSLEK 68 Query: 57 CKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFV 116 + + M+ A + + +L + G ID +++ N + G F+ Sbjct: 69 PRRIMLMVQAGAATDATI---KSLLPLLDIGDILIDGGNTHFPDTMRRNAELADSGINFI 125 Query: 117 EGPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKR--------SFYLGQVGNGAK 168 VSG +K A G ++ G K ++ P F+ + + Y+G G G Sbjct: 126 GTGVSGGEKGALLGP-SMMPGGQKEAYDLVAPIFEQIAAKAPQDGKPCVAYMGANGAGHY 184 Query: 169 MKLIVNMIMGSMMNAFSEGLVLADK-SGLSS---DTLLDILDLGAMTNPMFKGKGPSMNK 224 +K++ N I M +E L + GLS+ + + + G + + + + + + Sbjct: 185 VKMVHNGIEYGDMQLIAESYDLLKRILGLSNAEIQAIFEEWNEGELDSYLIEITKEVLKR 244 Query: 225 SSYPPAFPLKHQQKDMRLALALGD-------ENAVSMPV 256 + + D G + V +P+ Sbjct: 245 KDDEGEGYIVDKILDKAGNKGTGKWTSESALDLGVPLPL 283 >2ZYA-A nrPDB Length = 480 Score = 186 bits (471), Expect = 1e-47, Method: Composition-based stats. Identities = 48/273 (17%), Positives = 101/273 (36%), Gaps = 19/273 (6%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHG-------ASVCESPAEV 53 ++G +G+ +MG+ +++N+ G+ V+++NR+ K +E++ + E Sbjct: 16 QQIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVIAENPGKKLVPYYTVKEFVES 75 Query: 54 IKKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGG 113 ++ + + M+ + + + + +G ID + +++ N ++ +G Sbjct: 76 LETPRRILLMVKAGAGTDAAI---DSLKPYLDKGDIIIDGGNTFFQDTIRRNRELSAEGF 132 Query: 114 RFVEGPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKR-------SFYLGQVGNG 166 F+ VSG ++ A G I+ G K +E P + Y+G G G Sbjct: 133 NFIGTGVSGGEEGALKGP-SIMPGGQKEAYELVAPILTKIAAVAEDGEPCVTYIGADGAG 191 Query: 167 AKMKLIVNMIMGSMMNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSS 226 +K++ N I M +E L K GL+ N + K Sbjct: 192 HYVKMVHNGIEYGDMQLIAEAYSLL-KGGLNLTNEELAQTFTEWNNGELSSYLIDITKDI 250 Query: 227 YPPAFPLKHQQKDMRLALALGDENAVSMPVAAA 259 + + D+ L A +A Sbjct: 251 FTKKDEDGNYLVDVILDEAANKGTGKWTSQSAL 283 >3L6D-A nrPDB Length = 306 Score = 186 bits (471), Expect = 1e-47, Method: Composition-based stats. Identities = 62/292 (21%), Positives = 110/292 (37%), Gaps = 6/292 (2%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60 +V +GLG MG M+ LLK G +V +WNR+ K LV GA +CES + T Sbjct: 10 FDVSVIGLGAMGTIMAQVLLKQGKRVAIWNRSPGKAAALVAAGAHLCESVKAALSASPAT 69 Query: 61 IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120 I +L D A V+ G + + + +D +T + L + + GG +V+G + Sbjct: 70 IFVLLDNHATHEVLGMPG--VARALAHRTIVDYTTNAQDEGLALQGLVNQAGGHYVKGMI 127 Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 180 + + + GD+ FE+ + L + +L +++ + Sbjct: 128 VAYPRNVGHRESHSIHTGDREAFEQHRALLEGLAGHTVFLPWD-EALAFATVLHAHAFAA 186 Query: 181 MNAFSEGLVLADKSGLSSDTLLDIL--DLGAMTNPMFKGKGPSMNKSSYPPA-FPLKHQQ 237 M F E + D+ GL +L + + + L Sbjct: 187 MVTFFEAVGAGDRFGLPVSKTARLLLETSRFFVADALEEAVRRLETQDFKGDQARLDVHA 246 Query: 238 KDMRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVKFSRE 289 V PV A + ++A ++G GD D +A ++ +E Sbjct: 247 DAFAHIAQSLHAQGVWTPVFDAVCQVVQRAAAMGYGDQDIAATTKSFAREQE 298 >6FQY-A nrPDB Length = 468 Score = 169 bits (428), Expect = 1e-42, Method: Composition-based stats. Identities = 57/287 (19%), Positives = 106/287 (36%), Gaps = 30/287 (10%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDE---------LVEHGASVCESPAE 52 ++G +GL +MG+ +S+N+ GFK+ V+NRT + +E LV +G E Sbjct: 3 DIGLIGLAVMGQNLSLNISSKGFKIGVYNRTYERTEETMKRAKEENLVVYGYKTVEELIN 62 Query: 53 VIKKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKG 112 +KK + I ++ A + +L+ +G ID S + + K Sbjct: 63 NLKKPRKVILLIKAGPAVDE---NISNILKHFEKGDIIIDGGNEWYINSERRIKLCKEKD 119 Query: 113 GRFVEGPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKR------SFYLGQVGNG 166 ++ VSG + A G + G K ++ + + Y+G +G Sbjct: 120 VEYLAMGVSGGEAGARYG-CSFMPGGSKYAYDCVKEILEKCSAQVGNSPCVTYIGPGSSG 178 Query: 167 AKMKLIVNMIMGSMMNAFSEGLVLADK-SGLSSDTLLDIL---DLGAMTNPMFKGKGPSM 222 +K++ N I M SE V+ + L ++ + G + + + + + Sbjct: 179 NYVKMVHNGIEYGDMQLISESYVIMKHILKYDNQKLSEVFNKWNEGILNSYLIEITANIL 238 Query: 223 NKSSYPPAFPLKHQQKDMRLALALGD-------ENAVSMPVAAAANE 262 K L D+ A G E + P AA + Sbjct: 239 AKKDDLTNNYLVDMILDIAGAKGTGKWTMLEATERGIPCPTMCAALD 285 >6EOI-A nrPDB Length = 298 Score = 169 bits (427), Expect = 2e-42, Method: Composition-based stats. Identities = 62/292 (21%), Positives = 103/292 (35%), Gaps = 10/292 (3%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61 ++ GLG MG AM+ LK G TVWNRT +K + LVE GA + + I I Sbjct: 9 KLTIFGLGAMGTAMATQFLKQGHTPTVWNRTAAKANPLVEQGAHLAATIPAAIAASPLLI 68 Query: 62 AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121 L D A + GK ++++ + ++ + +G R+ G + Sbjct: 69 FCLLDNAAVEQTLAAG----PPSLAGKTILNLTNGTPSQARRLATLASARGARYFHGGIM 124 Query: 122 GSKKPAEDGQLIILA--AGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGS 179 + +IL G + VLG + G+ + L + M Sbjct: 125 ATPDMIGAPHAVILYSGGGSAETYASVEGVLAVLGSGKYLGDDAGSASLHDLALLSGMYG 184 Query: 180 MMNAFSEGLVLADK--SGLSSDTLLDILD-LGAMTNPMFKGKGPSMNKSSY-PPAFPLKH 235 + F L G+S+ L +L ++ Y L+ Sbjct: 185 LFAGFLHATALVRSEGEGVSATEFLGLLAPWLQAMTGYLGLLARQIDDGVYTAQTSNLEM 244 Query: 236 QQKDMRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVIEAVKFS 287 Q + A A E VS V ++A G G D S++I+ + + Sbjct: 245 QLVALENACAASREQGVSAEVMLPLKGLVERAVREGRGGHDISSLIDYFRNA 296 >4E21-A nrPDB Length = 358 Score = 168 bits (426), Expect = 2e-42, Method: Composition-based stats. Identities = 54/244 (22%), Positives = 90/244 (36%), Gaps = 34/244 (13%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKK-CKY 59 M++G +GLG MG M L K G + V++ ++ L G + S E K K Sbjct: 23 MQIGMIGLGRMGADMVRRLRKGGHECVVYDLNVNAVQALEREGIAGARSIEEFCAKLVKP 82 Query: 60 TIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGP 119 + L P A + + + L + ID + ++ + + +G +V+ Sbjct: 83 RVVWLMVPAAVVDSMLQRMTPL--LAANDIVIDGGNSHYQDDIRRADQMRAQGITYVDVG 140 Query: 120 VSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRS--------------------FY 159 SG E G ++ G+K E P F L + Sbjct: 141 TSGGIFGLERGYC-LMIGGEKQAVERLDPVFRTLAPGIGAAPRTPGREKREGTAELGYLH 199 Query: 160 LGQVGNGAKMKLIVNMIMGSMMNAFSEGLVL-----ADKSGLSSDTLLDILDLGAMTNPM 214 G G G +K++ N I +M A++EGL + A K G +D + + NP Sbjct: 200 CGPSGAGHFVKMVHNGIEYGLMAAYAEGLNILHHANAGKEGQGADA-----ETAPLRNPD 254 Query: 215 FKGK 218 F Sbjct: 255 FYRY 258 >1PGJ-A nrPDB Length = 478 Score = 159 bits (403), Expect = 9e-40, Method: Composition-based stats. Identities = 53/276 (19%), Positives = 104/276 (37%), Gaps = 32/276 (11%) Query: 13 KAMSMNLLKNGFKVTVWNRTLSKCDELVEHGAS-----------VCESPAEVIKKCKYTI 61 +++N+ + GFKV V+NRT SK +E ++ AS E+ A +KK + + Sbjct: 14 ANLALNIAEKGFKVAVFNRTYSKSEEFMKANASAPFAGNLKAFETMEAFAASLKKPRKAL 73 Query: 62 AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121 ++ A S + V E +G +D + + + + G RF+ +S Sbjct: 74 ILVQAGAATDSTIEQLKKVFE---KGDILVDTGNAHFKDQGRRAQQLEAAGLRFLGMGIS 130 Query: 122 GSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKR-------SFYLGQVGNGAKMKLIVN 174 G ++ A G G +++EE P + + G G G+ +K+ N Sbjct: 131 GGEEGARKGP-AFFPGGTLSVWEEIRPIVEAAAAKADDGRPCVTMNGSGGAGSCVKMYHN 189 Query: 175 MIMGSMMNAFSEGLVLADKSGLSSDTLLDILD----LGAMTNPMFKGKGPSMNKSSYPPA 230 +++ + E + GL++D + +L+ + + M + + Sbjct: 190 SGEYAILQIWGEVFDILRAMGLNNDEVAAVLEDWKSKNFLKSYMLDISIAAARAKDKDGS 249 Query: 231 FPLKH-----QQKDMRL-ALALGDENAVSMPVAAAA 260 + +H K L + E V P A Sbjct: 250 YLTEHVMDRIGSKGTGLWSAQEALEIGVPAPSLNMA 285 >1PGO-A nrPDB Length = 482 Score = 146 bits (369), Expect = 8e-36, Method: Composition-based stats. Identities = 45/222 (20%), Positives = 86/222 (38%), Gaps = 20/222 (9%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVE--------HGASVCESPAEV 53 ++ +GL +MG+ + +N+ +GF V +NRT+SK D+ + GA E Sbjct: 4 DIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVLGAHSLEEMVSK 63 Query: 54 IKKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGG 113 +KK + I ++ A + + +L+ + + +++ + KG Sbjct: 64 LKKPRRIILLVKAGQAVDNFIEKLVPLLDIGDIIIDGGNS---EYRDTMRRCRDLKDKGI 120 Query: 114 RFVEGPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRS-------FYLGQVGNG 166 FV VSG + A G ++ G+K + F + + ++G G G Sbjct: 121 LFVGSGVSGGEDGARYGP-SLMPGGNKEAWPHIKAIFQGIAAKVGTGEPCCDWVGDDGAG 179 Query: 167 AKMKLIVNMIMGSMMNAFSEGLVLAD-KSGLSSDTLLDILDL 207 +K++ N I M E L GL + + Sbjct: 180 HFVKMVHNGIEYGDMQLICEAYHLMKDVLGLGHKEMAKAFEE 221 >4GWK-A nrPDB Length = 484 Score = 140 bits (354), Expect = 4e-34, Method: Composition-based stats. Identities = 46/221 (20%), Positives = 90/221 (40%), Gaps = 20/221 (9%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEH--------GASVCESPAEV 53 ++ +GL +MG+ + +N+ +GF V +NRT+SK D+ + + GA + Sbjct: 6 DIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKEMVSK 65 Query: 54 IKKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGG 113 +KK + I ++ A + ++ + G ID + + + + KG Sbjct: 66 LKKPRRIILLVKAGQAVDDFIEK---LVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKGI 122 Query: 114 RFVEGPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRS-------FYLGQVGNG 166 FV VSG ++ A G ++ G+K + F + + ++G G G Sbjct: 123 LFVGSGVSGGEEGARYGP-SLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGAG 181 Query: 167 AKMKLIVNMIMGSMMNAFSEGLVLAD-KSGLSSDTLLDILD 206 +K++ N I M E L G++ D + + Sbjct: 182 HFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFE 222 >2P4Q-A nrPDB Length = 497 Score = 140 bits (354), Expect = 4e-34, Method: Composition-based stats. Identities = 57/292 (19%), Positives = 110/292 (37%), Gaps = 28/292 (9%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEH--------GASVCESPAEV 53 + G +GL +MG+ + +N +GF V +NRT SK D + + GA+ E Sbjct: 12 DFGLIGLAVMGQNLILNAADHGFTVCAYNRTQSKVDHFLANEAKGKSIIGATSIEDFISK 71 Query: 54 IKKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGG 113 +K+ + + ++ +++ ++ + +G ID S + E + KG Sbjct: 72 LKRPRKVMLLVKAGAPVDALINQ---IVPLLEKGDIIIDGGNSHFPDSNRRYEELKKKGI 128 Query: 114 RFVEGPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSF------YLGQVGNGA 167 FV VSG ++ A G ++ G + + F + +S ++G G G Sbjct: 129 LFVGSGVSGGEEGARYGP-SLMPGGSEEAWPHIKNIFQSISAKSDGEPCCEWVGPAGAGH 187 Query: 168 KMKLIVNMIMGSMMNAFSEGLVLADK-SGLSSDTLLDIL---DLGAMTNPMFKGKGPSMN 223 +K++ N I M E + + G + + D+ + G + + + + + Sbjct: 188 YVKMVHNGIEYGDMQLICEAYDIMKRLGGFTDKEISDVFAKWNNGVLDSFLVEI-TRDIL 246 Query: 224 KSSYPPAFPLKHQQKDMRLALALGD-----ENAVSMPVAAAANEAFKKARSL 270 K PL + D G + MPV F + S Sbjct: 247 KFDDVDGKPLVEKIMDTAGQKGTGKWTAINALDLGMPVTLIGEAVFARCLSA 298 >4R16-A nrPDB Length = 418 Score = 66.7 bits (161), Expect = 1e-11, Method: Composition-based stats. Identities = 49/297 (16%), Positives = 95/297 (31%), Gaps = 43/297 (14%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLS-------------------KCDELVE 41 M + LGLG +G ++ +G+ V ++ + E++ Sbjct: 1 MRIAVLGLGYIGLPTAIMFASSGYDVVGYDIRSEVIKKINSGVAHIIEPEIDRRLKEVLS 60 Query: 42 HGASVCESPAEVIKKCKYTIAMLSDPCAALSVVF-----DKGGVLEQICEGKGYIDMSTV 96 G E +K I + P + V E + G I ST+ Sbjct: 61 LGKLKVTDRVEDLKGSNVFIICVQTPLSGDDPDLSYLERAIRTVAEVMDRGALVIIESTI 120 Query: 97 DAETSLKINEAITG-----KGGRF--VEGP---VSGSKKPAEDGQLIILAAGDKALFEES 146 T+ K+ + +G F P + G I+ + + Sbjct: 121 PPGTTEKMARLLENLTGLREGVDFYVAHAPERVMPGRIFKELVYNSRIIGGVSEKAANLA 180 Query: 147 IPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMMNAFSEGLVLADKSGLSSDTLLDILD 206 + K +L +KL+ N + +E +LA + G++ + + ++ Sbjct: 181 EKLYRSFVKGRIFLTNATTAEMVKLMENTFRDVNIALANEFALLAHQYGVN---VYEAIE 237 Query: 207 LGAMTNPMFKGKGPSMNKSSY----PPAFPLKHQQKDMRLALALGDENAVSMPVAAA 259 L T+P K P + + P L + ++D L + + MP AA Sbjct: 238 LAN-THPRVKIHTPGIGVGGHCLPKDPYLLLSNAKEDFGL-IRIARRINERMPAFAA 292 >2Y0D-A nrPDB Length = 478 Score = 58.6 bits (140), Expect = 3e-09, Method: Composition-based stats. Identities = 48/309 (15%), Positives = 91/309 (29%), Gaps = 57/309 (18%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCE------------ 48 M + +G G +G L G V + +K D L G + E Sbjct: 9 MNLTIIGSGKVGLVTGACLADIGHDVFCLDVDQAKIDILNNGGVPIHEPGLKEVIARNRS 68 Query: 49 --------SPAEVIKKCKYTIAMLSDP------CAALSVVFDKGGVLEQICEGKGYIDMS 94 + + P V+ + + K +D S Sbjct: 69 AGRLRFSTDIEAAVAHGDVQFIAVGTPPDEDGSADLQYVLAAARNIGRYMTGFKVIVDKS 128 Query: 95 TVDAETSLK----INEAITGKGGRFVEGPVSGSK---KPAE----DGQLIILAAGDKAL- 142 TV T+ + + E + +GG + VS + + A I+ D + Sbjct: 129 TVPVGTAERVRAAVAEELAKRGGDQMFSVVSNPEFLKEGAAVDDFTRPDRIVIGCDDDVP 188 Query: 143 FEESIPAFDVLGK-------RSFYLGQVGNGAKMKLIVNMIMGSMMNAFSEGLVLADKSG 195 E + L R+ Y+ V + K N ++ + ++ +E LAD+ G Sbjct: 189 GERARELMKKLYAPFNRNHERTLYM-DVRSAEFTKYAANAMLATRISFMNELANLADRFG 247 Query: 196 LSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPP-AFPLKHQQKDMRLALALGDENAVSM 254 + + + F Y + KD+ + DE+ S+ Sbjct: 248 ADIEAVRRGIGSDPRIGYHF----------LYAGCGYGGSCFPKDVEALIRTADEHGQSL 297 Query: 255 PVAAAANEA 263 + A + Sbjct: 298 QILKAVSSV 306 >2F1K-A nrPDB Length = 279 Score = 55.9 bits (133), Expect = 2e-08, Method: Composition-based stats. Identities = 34/262 (12%), Positives = 84/262 (32%), Gaps = 47/262 (17%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHG-ASVCESPAEVIKKCKY 59 M++G +GLG++G +++ +L + G + +R S C++ VE +++ K Sbjct: 1 MKIGVVGLGLIGASLAGDLRRRGHYLIGVSRQQSTCEKAVERQLVDEAGQDLSLLQTAKI 60 Query: 60 TIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGP 119 ++ ++ + D+++V I E + F+ G Sbjct: 61 IFLCTP----IQLILPTLEKLIPHLSPTAIVTDVASV----KTAIAEPASQLWSGFIGGH 112 Query: 120 VSGSK--KPAEDGQLIILAAG----------DKALFEESIPAFDVLGKRSFYLGQVGNGA 167 + + + + D + LG + + + Sbjct: 113 PMAGTAAQGIDGAEENLFVNAPYVLTPTEYTDPEQLACLRSVLEPLGVKIYLCTPADHDQ 172 Query: 168 KMKLIVN---MIMGSMMNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNK 224 + I + M+ +++ A + +K G DIL L ++ Sbjct: 173 AVAWISHLPVMVSAALIQACA-----GEKDG-------DILKLA-----------QNLAS 209 Query: 225 SSYPPAFPLKHQQKDMRLALAL 246 S + + ++ +A Sbjct: 210 SGFRDTSRVGGGNPELGTMMAT 231 >2D0I-A nrPDB Length = 333 Score = 49.3 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 5/109 (4%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61 +VG LG+G +GKA++ L+ G K+ W+R K + E A + E+++K I Sbjct: 148 KVGILGMGAIGKAIARRLIPFGVKLYYWSRHR-KVNVEKELKARYMD-IDELLEKSDIVI 205 Query: 62 AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITG 110 L ++ ++ + EGK +++ + EAI Sbjct: 206 LALPLTRDTYHIINEER---VKKLEGKYLVNIGRGALVDEKAVTEAIKQ 251 >4DGS-A nrPDB Length = 340 Score = 49.3 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 20/109 (18%), Positives = 46/109 (42%), Gaps = 7/109 (6%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61 +G LGLG +G+A++ G V WNR+ + + H +SP ++ + Sbjct: 173 RIGVLGLGQIGRALASRAEAFGMSVRYWNRSTLSGVDWIAH-----QSPVDLARDSDVLA 227 Query: 62 AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITG 110 ++ A ++V +L+ + ++++ + + EA+ Sbjct: 228 VCVAASAATQNIVDA--SLLQALGPEGIVVNVARGNVVDEDALIEALKS 274 >3OJO-A nrPDB Length = 431 Score = 47.4 bits (111), Expect = 8e-06, Method: Composition-based stats. Identities = 52/304 (17%), Positives = 93/304 (30%), Gaps = 43/304 (14%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESP------AEVI- 54 ++ +GLG +G S+ K+G V + D+L ++G E P EV+ Sbjct: 13 KLTVVGLGYIGLPTSIMFAKHGVDVLGVDINQQTIDKL-QNGQISIEEPGLQEVYEEVLS 71 Query: 55 ----------KKCKYTIAMLSDPCAALS--------VVFDKGGVLEQICEGKGYIDMSTV 96 + I + P V+ +L + +G I ST+ Sbjct: 72 SGKLKVSTTPEASDVFIIAVPTPNNDDQYRSCDISLVMRALDSILPFLKKGNTIIVESTI 131 Query: 97 DAETSLKINEAITG-------KGGRFVEGP--VSGSKKPAEDGQLIILAAG-DKALFEES 146 +T + + + V P V K E + G KA E Sbjct: 132 APKTMDDFVKPVIENLGFTIGEDIYLVHCPERVLPGKILEELVHNNRIIGGVTKACIEAG 191 Query: 147 IPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMMNAFSEGLVLADKSGLSSDTLLDILD 206 + + KL+ N + +E + + ++ ++++ + Sbjct: 192 KRVYRTFVQGEMIETDARTAEMSKLMENTYRDVNIALANELTKICNNLNINVLDVIEMAN 251 Query: 207 LGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDMRLA--LALGDENAVSMP--VAAAANE 262 N G G + + P F KD A + G E SMP V + Sbjct: 252 KHPRVNIHQPGPGVGGHCLAVDPYF---IIAKDPENAKLIQTGREINNSMPAYVVDTTKQ 308 Query: 263 AFKK 266 K Sbjct: 309 IIKA 312 >4OM8-A nrPDB Length = 309 Score = 47.0 bits (110), Expect = 9e-06, Method: Composition-based stats. Identities = 28/246 (11%), Positives = 69/246 (28%), Gaps = 39/246 (15%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCD------------------ELVEHGA 44 + +GLG MG M+ L + G +V ++ + + L G Sbjct: 5 IAIIGLGTMGPGMAARLARGGLQVVAYDVAPAAIERARSMLSVAETVLDALGIALPSAGV 64 Query: 45 SVCE---SPAEVIKKCKYTIAMLSDPCAAL-SVVFDKGGVLEQICEGKGYIDMSTVDAET 100 + + I + + + V G+ I + ++ T Sbjct: 65 GTVRFTDDIGDAVSGADLVIENVPENISIKADVYRTIDGL---IGQDTIVASDTSGIPIT 121 Query: 101 SLKINEAITGK--GGRFVEGPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSF 158 L+ + + + G + P G+ +G Sbjct: 122 KLQAHISYPERMVGMHWSNPPHIIPMIEVIAGEKTA-----PQTVATIRDLIRSIGLLPV 176 Query: 159 YLGQVGNGAKMKLIVNMIMGSMMNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGK 218 + + G + N ++ +++ E + L ++ + + L + G G Sbjct: 177 VVKKDVPG----FVENRVLYALLR---EAVDLVERGVIDPEDLDTCVSWGIGYKIAVIGP 229 Query: 219 GPSMNK 224 ++ Sbjct: 230 MALLDM 235 >2WWR-A nrPDB Length = 330 Score = 46.2 bits (108), Expect = 2e-05, Method: Composition-based stats. Identities = 27/167 (16%), Positives = 60/167 (35%), Gaps = 8/167 (4%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62 VG +GLG +G+A++ L G + ++ + +E E A +P E+ + + + Sbjct: 158 VGIIGLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTP-ELAAQSDFIVV 216 Query: 63 MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSG 122 S A + +++ E +I++S D + +A+ V+ Sbjct: 217 ACSLTPATEGLCN--KDFFQKMKETAVFINISRGDVVNQDDLYQALASGKIAAAGLDVTS 274 Query: 123 SKKPAEDGQLIILAAGD-----KALFEESIPAFDVLGKRSFYLGQVG 164 + + L+ L + + +L + G G Sbjct: 275 PEPLPTNHPLLTLKNCVILPHIGSATHRTRNTMSLLAANNLLAGLRG 321 >5AOV-A nrPDB Length = 336 Score = 46.2 bits (108), Expect = 2e-05, Method: Composition-based stats. Identities = 17/108 (15%), Positives = 46/108 (42%), Gaps = 4/108 (3%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62 +G +G G +G+A++ ++ ++RT K E GA EV+K+ + I Sbjct: 153 IGIVGFGRIGQAIARRAKGFNMRILYYSRTR-KSQAEKELGAEY-RPLEEVLKESDFVIL 210 Query: 63 MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITG 110 + + ++ ++ L+ + ++++ + + +A+ Sbjct: 211 AVPLTKETMYMINEER--LKLMKPTAILVNIARGKVVDTKALIKALKE 256 >4YPO-A nrPDB Length = 333 Score = 45.9 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 23/89 (25%), Positives = 37/89 (41%), Gaps = 3/89 (3%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61 +VG +G G G A S++L +G +V V + S+ VE ++PAEV K + Sbjct: 16 KVGVIGYGSQGHAHSLSLRDSGVQVRVGLKQGSRSRPKVEEQGLDVDTPAEVAKWADVVM 75 Query: 62 AMLSDPCAALSVVFDKGGVLEQICEGKGY 90 + D A G + + G Sbjct: 76 VLAPDTAQAE---IFAGDIEPNLKPGDAL 101 >1GPJ-A nrPDB Length = 404 Score = 45.5 bits (106), Expect = 3e-05, Method: Composition-based stats. Identities = 20/93 (21%), Positives = 39/93 (41%), Gaps = 4/93 (4%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFK-VTVWNRTLSKCDELVE-HG--ASVCESPAEVIKKCK 58 V +G G MGK ++ +L+ G + V V NRT + EL G A + + + + Sbjct: 170 VLVVGAGEMGKTVAKSLVDRGVRAVLVANRTYERAVELARDLGGEAVRFDELVDHLARSD 229 Query: 59 YTIAMLSDPCAALSVVFDKGGVLEQICEGKGYI 91 ++ + P + V + + ++ I Sbjct: 230 VVVSATAAPHPVIHVDDVREALRKRDRRSPILI 262 >3KBO-A nrPDB Length = 315 Score = 45.1 bits (105), Expect = 3e-05, Method: Composition-based stats. Identities = 23/128 (17%), Positives = 51/128 (39%), Gaps = 15/128 (11%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60 VG +G G++G ++ +L GF + W+R+ K VE E + + + Sbjct: 140 FSVGIMGAGVLGAKVAESLQAWGFPLRCWSRSR-KSWPGVES-YVGREELRAFLNQTRVL 197 Query: 61 IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120 I +L + + ++ + +L+Q+ +G ++ + + + + Sbjct: 198 INLLPNTAQTVGIINSE--LLDQLPDGAYVLN-----------LARGVHVQEADLLAALD 244 Query: 121 SGSKKPAE 128 SG K A Sbjct: 245 SGKLKGAM 252 >6HD1-C nrPDB Length = 459 Score = 44.3 bits (103), Expect = 5e-05, Method: Composition-based stats. Identities = 34/162 (20%), Positives = 59/162 (36%), Gaps = 19/162 (11%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62 V G G G+++ + +L+ G+ V +R K L+ GA S +E KK I Sbjct: 22 VCIFGTGDFGRSLGLKMLQCGYSVVFGSRNPQKTT-LLPSGAE-VLSYSEAAKKSGIIII 79 Query: 63 MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTV-----DAETSLKINEAITGKGGRFVE 117 A +D L ++ GK +D+S E++ + + G V+ Sbjct: 80 ------AIHREHYDFLTELTEVLNGKILVDISNNLKINQYPESNAEYLAHLVP-GAHVVK 132 Query: 118 GP--VSGS--KKPAEDGQLIILAAG-DKALFEESIPAFDVLG 154 +S + A D + G D + + LG Sbjct: 133 AFNTISAWALQSGALDASRQVFVCGNDSKAKQRVMDIVRNLG 174 >4G2N-A nrPDB Length = 345 Score = 44.3 bits (103), Expect = 7e-05, Method: Composition-based stats. Identities = 24/110 (21%), Positives = 46/110 (41%), Gaps = 4/110 (3%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61 +G G+G +G+A++ G + NRT + +E GA ++ ++ I Sbjct: 175 RLGIFGMGRIGRAIATRARGFGLAIHYHNRT--RLSHALEEGAIYHDTLDSLLGASD--I 230 Query: 62 AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGK 111 +++ P F + +I EG I++S D + EA+ K Sbjct: 231 FLIAAPGRPELKGFLDHDRIAKIPEGAVVINISRGDLINDDALIEALRSK 280 >4N18-A nrPDB Length = 332 Score = 43.9 bits (102), Expect = 8e-05, Method: Composition-based stats. Identities = 14/94 (14%), Positives = 36/94 (38%), Gaps = 4/94 (4%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60 +G +GLG +G ++ L + G++V+ W+R+ + + + + Sbjct: 157 FHIGIMGLGEIGGYIADQLARLGYRVSGWSRSEKQLAGVTCYRGEEALD--HFLGSLDGL 214 Query: 61 IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMS 94 I +L ++ + ++ G I+ Sbjct: 215 INLLPLTAQTRGILAAP--LFNRLPAGAVLINCG 246 >3TRI-A nrPDB Length = 280 Score = 43.9 bits (102), Expect = 9e-05, Method: Composition-based stats. Identities = 18/100 (18%), Positives = 36/100 (36%), Gaps = 5/100 (5%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFK---VTVWNRTLSKCDELVEH-GASVCESPAEVIKKCK 58 + F+G G M + + + L+ NG+ + V NR+L K D E G + + Sbjct: 6 ITFIGGGNMARNIVVGLIANGYDPNRICVTNRSLDKLDFFKEKCGVHTTQDNRQGALNAD 65 Query: 59 YTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDA 98 + + P V + +L + + + Sbjct: 66 VVVLAVK-PHQIKMVCEELKDILSETKILVISLAVGVTTP 104 >5WHX-A nrPDB Length = 271 Score = 43.5 bits (101), Expect = 9e-05, Method: Composition-based stats. Identities = 18/138 (13%), Positives = 51/138 (36%), Gaps = 6/138 (4%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60 +++G +G G G+ ++ ++K G +T +R+ + ++ G + + Sbjct: 10 LKIGIVGFGNFGQFLAKTMIKQGHTLTATSRS-DYSELCLQMGIHFFRDVSAFLTADIDV 68 Query: 61 IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120 I + + + VV L + ++D+ +V E ++ + + Sbjct: 69 IVLCTSILSLSEVVGSM--PLTSLKRPTLFVDVLSVK-EHPRELLLRELPEDSDILCTHP 125 Query: 121 SGSKKPAEDG--QLIILA 136 + A++G + Sbjct: 126 MFGPQTAKNGWTDHTFMY 143 >3GGO-A nrPDB Length = 314 Score = 43.5 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 34/206 (16%), Positives = 71/206 (34%), Gaps = 29/206 (14%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGF--KVTVWNRTLSKCDELVEHGAS-VCESPAEVIKKC 57 V +G+G MG + + +L ++GF K+ ++ + V+ G + ++ Sbjct: 34 QNVLIVGVGFMGGSFAKSLRRSGFKGKIYGYDINPESISKAVDLGIIDEGTTSIAKVEDF 93 Query: 58 KYTIAMLSDPCAALSVV---------FDKGGVLEQICEGKGYIDMSTVDAETSLKINEAI 108 MLS P + D + +GK D+ + Sbjct: 94 SPDFVMLSSPVRTFREIAKKLSYILSEDATVTDQGSVKGKLVYDLENI------------ 141 Query: 109 TGKGGRFVEG-PVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGA 167 G RFV G P++G++K + L L G K + + K + + G Sbjct: 142 --LGKRFVGGHPIAGTEKSGVEYSLDNLYEGKKVILTPTKKTDKKRLKLVKRVWEDVGGV 199 Query: 168 KMKLI--VNMIMGSMMNAFSEGLVLA 191 + ++ + +++ + A Sbjct: 200 VEYMSPELHDYVFGVVSHLPHAVAFA 225 >2G5C-A nrPDB Length = 281 Score = 43.5 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 34/206 (16%), Positives = 71/206 (34%), Gaps = 29/206 (14%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGF--KVTVWNRTLSKCDELVEHGAS-VCESPAEVIKKC 57 V +G+G MG + + +L ++GF K+ ++ + V+ G + ++ Sbjct: 2 QNVLIVGVGFMGGSFAKSLRRSGFKGKIYGYDINPESISKAVDLGIIDEGTTSIAKVEDF 61 Query: 58 KYTIAMLSDPCAALSVV---------FDKGGVLEQICEGKGYIDMSTVDAETSLKINEAI 108 MLS P + D + +GK D+ + Sbjct: 62 SPDFVMLSSPVRTFREIAKKLSYILSEDATVTDQGSVKGKLVYDLENI------------ 109 Query: 109 TGKGGRFVEG-PVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGA 167 G RFV G P++G++K + L L G K + + K + + G Sbjct: 110 --LGKRFVGGHPIAGTEKSGVEYSLDNLYEGKKVILTPTKKTDKKRLKLVKRVWEDVGGV 167 Query: 168 KMKLI--VNMIMGSMMNAFSEGLVLA 191 + ++ + +++ + A Sbjct: 168 VEYMSPELHDYVFGVVSHLPHAVAFA 193 >4KQW-A nrPDB Length = 350 Score = 43.5 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 17/90 (18%), Positives = 33/90 (36%), Gaps = 3/90 (3%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60 ++VG +G G G A ++NL+ +G V V R S + E ++ Sbjct: 28 LKVGIIGYGSQGHAHALNLMDSGVDVRVGLREGSSSWKTAEEAGLKVTDMDTAAEEADVI 87 Query: 61 IAMLSDPCAALSVVFDKGGVLEQICEGKGY 90 + ++ D V + + + G Sbjct: 88 MVLVPDEIQ-PKVY--QEHIAAHLKAGNTL 114 >6BII-A nrPDB Length = 333 Score = 42.8 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 14/108 (12%), Positives = 43/108 (39%), Gaps = 4/108 (3%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62 +G +G G +G+A++ G ++ R+ K + E GA E++++ + + Sbjct: 153 IGIVGFGRIGQAIAKRAKGFGMRILYTARSR-KPEAEKELGAEFKP-LEELLRESDFVVL 210 Query: 63 MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITG 110 + ++ ++ L + ++++ + + A+ Sbjct: 211 AVPLTKETYHMINEER--LRLMKPTAVLVNVARGKVVDTKALIRALKE 256 >1MV8-A nrPDB Length = 436 Score = 42.4 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 34/247 (13%), Positives = 76/247 (30%), Gaps = 44/247 (17%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKC---------------DELVEHGAS 45 M + GLG +G + L G +V + + +K + L++ G Sbjct: 1 MRISIFGLGYVGAVCAGCLSARGHEVIGVDVSSTKIDLINQGKSPIVEPGLEALLQQGRQ 60 Query: 46 VCE-----SPAEVIKKCKYTIAMLSDPCA---------ALSVVFDKGGVLEQICEGKGYI 91 + + + + P +V + G + + E + Sbjct: 61 TGRLSGTTDFKKAVLDSDVSFICVGTPSKKNGDLDLGYIETVCREIGFAIREKSERHTVV 120 Query: 92 DMSTVDAET----SLKINEAITGKGGRFVEGPVSGSKKPAED---------GQLIILAAG 138 STV T + + E +GK V+ V + + + + ++ Sbjct: 121 VRSTVLPGTVNNVVIPLIEDCSGKKAG-VDFGVGTNPEFLRESTAIKDYDFPPMTVIGEL 179 Query: 139 DKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMMNAFSEGLVLADKSGLSS 198 DK + + L V +K N+ + + +E +A G+ Sbjct: 180 DKQTGDLLEEIYRELDAPIIR-KTVEVAEMIKYTCNVWHAAKVTFANEIGNIAKAVGVDG 238 Query: 199 DTLLDIL 205 ++D++ Sbjct: 239 REVMDVI 245 Score = 28.5 bits (62), Expect = 3.0, Method: Composition-based stats. Identities = 22/125 (17%), Positives = 48/125 (38%), Gaps = 19/125 (15%) Query: 2 EVGFLGLG-IMGKA---------MSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPA 51 +VG LGL G ++ L+ G+++ +++R + HGA+ + Sbjct: 315 KVGLLGLSFKAGTDDLRESPLVELAEMLIGKGYELRIFDRNVEYAR---VHGANKEYIES 371 Query: 52 EVIKKCKYTIAMLSDPCAALSVVFDKGG------VLEQICEGKGYIDMSTVDAETSLKIN 105 ++ ++ L + A+ V+ G ++ + GK +D+ T+ Sbjct: 372 KIPHVSSLLVSDLDEVVASSDVLVLGNGDELFVDLVNKTPSGKKLVDLVGFMPHTTTAQA 431 Query: 106 EAITG 110 E I Sbjct: 432 EGICW 436 >5UOG-A nrPDB Length = 344 Score = 42.4 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 19/106 (17%), Positives = 35/106 (33%), Gaps = 7/106 (6%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62 VG GLG +G A++ L G + RT G + + + + I Sbjct: 167 VGLFGLGRIGLAIARRLEAFGVSIAYHTRTPR-----EGLGFTYHPTLVGMAEAVDTLIV 221 Query: 63 MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAI 108 ++ + L V VL + I++ + A+ Sbjct: 222 IVPGTASTLKAVNA--DVLSALGPKGVLINVGRGSTVDEAALVTAL 265 >3VTF-A nrPDB Length = 444 Score = 42.4 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 41/304 (13%), Positives = 95/304 (31%), Gaps = 41/304 (13%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCE-SPAEVIKKC---- 57 + LGLG +G ++ G +V ++ S + L + E E + + Sbjct: 24 LSVLGLGYVGVVHAVGFALLGHRVVGYDVNPSIVERLRAGRPHIYEPGLEEALGRALSSG 83 Query: 58 ---------------KYTIAMLSDPCA---------ALSVVFDKGGVLEQICEGKGYIDM 93 T + P A + G + + Sbjct: 84 RLSFAESAEEAVAATDATFIAVGTPPAPDGSADLRYVEAAARAVGRGIRAKGRWHLVVVK 143 Query: 94 STVDAETSLKINEAITGKGGRFVEGPVSGSKKPAEDGQL---------IILAAGDKALFE 144 STV T+ + + V+ V+ + + +G I++ AGD+ Sbjct: 144 STVPPGTTEGLVARAVAEEAGGVKFSVASNPEFLREGSALEDFFKPDRIVIGAGDERAAS 203 Query: 145 ESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMMNAFSEGLVLADKSGLSSDTLLDI 204 + + + + +K N+ + ++ +E +LA + G+ + + + Sbjct: 204 FLLDVYKAVDAPKLVMKPR-EAELVKYASNVFLALKISFANEVGLLAKRLGVDTYRVFEA 262 Query: 205 LDLGAMTNPMFKGKGPSMNKSSYP-PAFPLKHQQKDMRLALALGDEN-AVSMPVAAAANE 262 + L + G G S +P + + L +A+ V+ + A + Sbjct: 263 VGLDKRIGRHYFGAGLGFGGSCFPKDTLAFIRFGESLGLEMAISKAVLRVNEYMPRYAVQ 322 Query: 263 AFKK 266 ++ Sbjct: 323 LLEE 326 >4EBF-A nrPDB Length = 334 Score = 42.4 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 26/189 (13%), Positives = 53/189 (28%), Gaps = 21/189 (11%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPA--EVIKKCKYT 60 VGFLG+G +G AM+ L G + +K + A E+ + Sbjct: 149 VGFLGMGAIGLAMADRLQGWGATLQYH---AAKALDTQTEQRLGLRQVACSELFASSDFI 205 Query: 61 IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120 + L L +V + +L + G ++ + A+ Sbjct: 206 LLALPLNADTLHLVNAE--LLALVRPGALLVNPCRGSVVDEAAVLAALER---------- 253 Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 180 + + + +A + L L G+ ++ + I Sbjct: 254 --GQLGGYAADVFEMEDWARA--DRPQQIDPALLAHPNTLFTPHIGSAVRAVRLEIERCA 309 Query: 181 MNAFSEGLV 189 + L Sbjct: 310 AQNILQALA 318 >2I99-A nrPDB Length = 312 Score = 42.4 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 22/132 (16%), Positives = 48/132 (36%), Gaps = 18/132 (13%) Query: 25 KVTVWNRTLSKCDELVE--HG-ASVCESPAEVIKKCKYTIAMLSDPCAALSVVFDKGGVL 81 +V +WNRT ++ + G VC S E + I + A ++F Sbjct: 162 EVRIWNRTKENAEKFADTVQGEVRVCSSVQEAVAGADVIITV---TLATEPILFG----- 213 Query: 82 EQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSGSKKPAEDGQLIILAAGDKA 141 E + G +I+ ++++ + + +V+ ++ A +L +G Sbjct: 214 EWVKPG-AHINAVGASRPDWRELDDELMKEAVLYVDS-----QEAALKESGDVLLSG-AE 266 Query: 142 LFEESIPAFDVL 153 +F E + Sbjct: 267 IFAELGEVIKGV 278 >4TSK-A nrPDB Length = 350 Score = 42.4 bits (98), Expect = 3e-04, Method: Composition-based stats. Identities = 14/99 (14%), Positives = 30/99 (30%), Gaps = 2/99 (2%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61 + +G G G A + NL +GF V + E + E +++ + Sbjct: 19 RIAVIGYGSQGHAHAQNLRDSGFDVVI-GLRPGSSWAKAEADGFRVMAVGEAVEESDVIM 77 Query: 62 AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAET 100 +L D +V + + + + Sbjct: 78 ILLPDERQ-PAVYEREIRPYLTAGKALAFAHGFNIHFSQ 115 >2HK7-A nrPDB Length = 269 Score = 41.6 bits (96), Expect = 3e-04, Method: Composition-based stats. Identities = 31/117 (26%), Positives = 50/117 (42%), Gaps = 8/117 (6%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGA-SVCESPAEVIKKCKYTI 61 + LG G +A+ L+K G KV +WNRT K +L + V SP EVI K + + Sbjct: 126 ILVLGAGGASRAVIYALVKEGAKVFLWNRTKEKAIKLAQKFPLEVVNSPEEVIDKVQVIV 185 Query: 62 AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEG 118 S + + I + +D + ET K+ + KG + ++G Sbjct: 186 NTTSVGLKDED---PEIFNYDLIKKDHVVVD--IIYKET--KLLKKAKEKGAKLLDG 235 >1NP3-A nrPDB Length = 338 Score = 41.6 bits (96), Expect = 4e-04, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 23/65 (35%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61 +V +G G G A + NL +G VTV R+ S E + + Sbjct: 18 KVAIIGYGSQGHAHACNLKDSGVDVTVGLRSGSATVAKAEAHGLKVADVKTAVAAADVVM 77 Query: 62 AMLSD 66 + D Sbjct: 78 ILTPD 82 >3MOG-A nrPDB Length = 483 Score = 41.6 bits (96), Expect = 4e-04, Method: Composition-based stats. Identities = 25/189 (13%), Positives = 55/189 (29%), Gaps = 44/189 (23%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVE-----------HGASVCESPA 51 V +G G MG ++ +G +V +++ + ++ G E+ Sbjct: 8 VAVIGSGTMGAGIAEVAASHGHQVLLYDISAEALTRAIDGIHARLNSRVTRGKLTAETCE 67 Query: 52 ------------EVIKKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAE 99 + I S+ +F + L ++C + + + + Sbjct: 68 RTLKRLIPVTDIHALAAADLVIEAASERLEVKKALFAQ---LAEVCPPQTLL-TTNTSSI 123 Query: 100 TSLKINEAITG----KGGRFVE-GPVSGSKKPAEDGQLIILAAG---DKALFEESIPAFD 151 + I I G F PV +L+ + +G + E+ Sbjct: 124 SITAIAAEIKNPERVAGLHFFNPAPVM---------KLVEVVSGLATAAEVVEQLCELTL 174 Query: 152 VLGKRSFYL 160 GK+ Sbjct: 175 SWGKQPVRC 183 >6C55-A nrPDB Length = 340 Score = 40.8 bits (94), Expect = 6e-04, Method: Composition-based stats. Identities = 14/65 (21%), Positives = 27/65 (41%), Gaps = 1/65 (1%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61 ++ +G G G A + NL NG+ V + + + + AE +K+ + Sbjct: 19 KIAVVGYGSQGHAHAQNLKDNGYDVVI-GIRPGRSFDKAKEDGFDVFPVAEAVKQADVIM 77 Query: 62 AMLSD 66 +L D Sbjct: 78 VLLPD 82 >2DLD-A nrPDB Length = 337 Score = 40.8 bits (94), Expect = 7e-04, Method: Composition-based stats. Identities = 19/92 (20%), Positives = 41/92 (44%), Gaps = 5/92 (5%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62 VG +G G +G+ + G KV ++ + EL + G +S ++ K+ Sbjct: 149 VGVVGTGHIGQVFMRIMEGFGAKVIAYDIFKNP--ELEKKGYY-VDSLDDLYKQADVISL 205 Query: 63 MLSDPCAALSVVFDKGGVLEQICEGKGYIDMS 94 + D A + ++ DK + ++ +G ++ S Sbjct: 206 HVPDVPANVHMINDKS--IAEMKDGVVIVNCS 235 >4XA8-A nrPDB Length = 320 Score = 40.8 bits (94), Expect = 8e-04, Method: Composition-based stats. Identities = 22/110 (20%), Positives = 45/110 (40%), Gaps = 4/110 (3%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60 + VG LGLG +G A ++ L ++GF V W+RT + + E+ + + Sbjct: 145 IRVGVLGLGDLGAAAALELARHGFDVRGWSRTPKALEGVSCF--HGLEALPGFLAGSEIV 202 Query: 61 IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITG 110 + ML ++ + L + G +I+++ + A+ Sbjct: 203 VVMLPLTPETRGLMNAER--LAHLPRGAKFINVARGPVVDEAALIAALRS 250 >1TXG-A nrPDB Length = 335 Score = 40.5 bits (93), Expect = 8e-04, Method: Composition-based stats. Identities = 30/171 (17%), Positives = 63/171 (36%), Gaps = 21/171 (12%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWN--------RTLSKCDELVEHGASV--CESP 50 M V LG G MG A+S+ L+ NG +V +W +++S E G + E Sbjct: 1 MIVSILGAGAMGSALSVPLVDNGNEVRIWGTEFDTEILKSISAGREHPRLGVKLNGVEIF 60 Query: 51 -AEVIKKCKYTIAMLSDPCAALSVVFDKGGVLEQIC--------EGKGYIDMSTVD-AET 100 E ++KC ++ + V+ +L + +G D S + E Sbjct: 61 WPEQLEKCLENAEVVLLGVSTDGVLPVMSRILPYLKDQYIVLISKGLIDFDNSVLTVPEA 120 Query: 101 SLKINEAITGKGGRFVEGPVSGSKKPAEDGQLIILAAGDKALFEESIPAFD 151 ++ + + + GP + ++ ++ ++ + F+ Sbjct: 121 VWRLKHDLRERTVA-ITGPAIAREVAKRMPTTVVFSSPSESSANKMKEIFE 170 >4WEQ-A nrPDB Length = 341 Score = 40.5 bits (93), Expect = 8e-04, Method: Composition-based stats. Identities = 16/123 (13%), Positives = 44/123 (35%), Gaps = 8/123 (6%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62 VG +G+G++G+ + L GFKV W+R+ + + + A+ + + + + + Sbjct: 164 VGIMGMGVLGQDAARKLAAMGFKVIGWSRSKRVIEGVETYDAAGLD---AFLGRTDFLVG 220 Query: 63 MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSG 122 +L + + ++ + + + + ++ V G Sbjct: 221 LLPLTPDTRGIFNAA--LFAKLSRNGPF---GAPVFINAGRGGSQVEADILECLDSGVLG 275 Query: 123 SKK 125 Sbjct: 276 GAS 278 >3JTM-A nrPDB Length = 351 Score = 40.5 bits (93), Expect = 9e-04, Method: Composition-based stats. Identities = 17/108 (15%), Positives = 41/108 (37%), Gaps = 2/108 (1%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62 +G +G G +GK + L G + +R + E GA E E++ KC + Sbjct: 167 IGTVGAGRIGKLLLQRLKPFGCNLLYHDRLQMAPELEKETGAKFVEDLNEMLPKCDVIVI 226 Query: 63 MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITG 110 + + + ++ ++ +G ++ + + +A+ Sbjct: 227 NMPLTEKTRGMFNKE--LIGKLKKGVLIVNNARGAIMERQAVVDAVES 272 >5B37-A nrPDB Length = 361 Score = 40.5 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 13/53 (24%), Positives = 26/53 (49%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEV 53 M+V GLG +GK + +L ++ ++ V + K +E+ + P E+ Sbjct: 170 MKVAVQGLGNVGKNLCRHLHEHDVQLFVSDVDPIKAEEVKRLFGATVVEPTEI 222 >1BG6-A nrPDB Length = 359 Score = 40.1 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 25/121 (20%), Positives = 41/121 (33%), Gaps = 12/121 (9%) Query: 4 GFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIAM 63 LGLG G A + L G V W+ + E+ + GA + E P + Sbjct: 8 AVLGLGNGGHAFAAYLALKGQSVLAWDIDAQRIKEIQDRGAIIAEGPGLAGTAHPDLLTS 67 Query: 64 -----LSDPCAALSVVFD------KGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKG 112 + D L VV + I EG+ I ++ +L+ + + G Sbjct: 68 DIGLAVKDADVILIVVPAIHHASIAANIASYISEGQLII-LNPGATGGALEFRKILRENG 126 Query: 113 G 113 Sbjct: 127 A 127 >3DC2-A nrPDB Length = 529 Score = 40.1 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 31/207 (14%), Positives = 69/207 (33%), Gaps = 23/207 (11%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWN--RTLSKCDELVEHGASVCESPAEVIKKCKYT 60 VG +GLG +G+ ++ + G V ++ + ++ +L S +++ + + Sbjct: 145 VGVVGLGRIGQLVAQRIAAFGAYVVAYDPYVSPARAAQL----GIELLSLDDLLARADFI 200 Query: 61 IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120 L ++ + L + G ++ + + +AITG Sbjct: 201 SVHLPKTPETAGLIDKEA--LAKTKPGVIIVNAARGGLVDEAALADAITG---------- 248 Query: 121 SGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSM 180 G + A D LFE + S Q G + V + + Sbjct: 249 -GHVRAAGLDVFATEPCTDSPLFELAQVVVTPHLGASTAEAQDRAGTDVAESVRLALAGE 307 Query: 181 MNAFSEGLVLADKSGLSSDTLLDILDL 207 + + + G+ ++ + LDL Sbjct: 308 F--VPDAVNVGG--GVVNEEVAPWLDL 330 >6G1M-A nrPDB Length = 338 Score = 39.7 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 20/135 (14%), Positives = 45/135 (33%), Gaps = 13/135 (9%) Query: 2 EVGFLGLGIMGKAMSMNLLKNG--FKVTVWNRTLSKCD-------ELVEHGASVCESPAE 52 +VG G G MG ++ N+L V V + + L + G V P Sbjct: 3 KVGIWGFGAMGSGIAKNILSKKNLKLVGVHDFREEYIEKDVGELLGLGKIGIKVYPDPIT 62 Query: 53 VIKKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMS----TVDAETSLKINEAI 108 ++K+ + +++ V +L++ + + D + + +I+ Sbjct: 63 MVKQTDPDLVVIATNSFISVVKDQIISILKENKNVITIAEEMAFPFSKDPKAANEIDTVA 122 Query: 109 TGKGGRFVEGPVSGS 123 + V+ Sbjct: 123 KDHNVSVLGTGVNPG 137 >5Z1Z-A nrPDB Length = 329 Score = 39.7 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 19/117 (16%), Positives = 39/117 (33%), Gaps = 5/117 (4%) Query: 4 GFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIAM 63 G +G G +G AM L G ++ ++ S +E G + P + + Sbjct: 148 GVIGTGKIGVAMLRILKGFGMRLLAFDPYPSAAA--LELGVEYVDLPT-LFSESDVISLH 204 Query: 64 LSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120 ++ + +Q+ G ++ S S EA+ + + V Sbjct: 205 CPLTPENYHLLNEAA--FDQMKNGVMIVNTSRGALIDSQAAIEALKNQKIGSLGMDV 259 >1YON-A nrPDB Length = 303 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 20/111 (18%), Positives = 36/111 (32%), Gaps = 9/111 (8%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSK--CDELVEH-----GASVCESPAEV 53 M++ LG G +G+ L K G +V W R LVE S+ + + Sbjct: 1 MKITVLGCGALGQLWLTALCKQGHEVQGWLRVPQPYCSVNLVETDGSIFNESLTANDPDF 60 Query: 54 IKKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYID-MSTVDAETSLK 103 + + L V L + M T++ +++ Sbjct: 61 LATSDLLLVTLKAW-QVSDAVKSLASTLPVTTPILLIHNGMGTIEELQNIQ 110 >5T57-A nrPDB Length = 296 Score = 38.9 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 30/227 (13%), Positives = 63/227 (27%), Gaps = 33/227 (14%) Query: 2 EVGFLGLG-IMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60 ++ G G MG ++ NLLK+ ++V+ + L + C S + Sbjct: 24 KIALFGAGGKMGVRLAKNLLKSDYRVSHVEVSEVGKKRLKDELGLECVSTEAALDNVDVV 83 Query: 61 IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDA-----ETSLKINEAIT------ 109 I + D + Q+ G + + + + Sbjct: 84 ILAVPDTIIGK----IAAQIAPQLRPGTMVMTLDAAAPFAGHLPDRPDLTYFVAHPCHPL 139 Query: 110 --------GKGGRFVEGPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSF--Y 159 + G A+ L G + F+ V+ Y Sbjct: 140 IFNDETDPEARRDYFGGG------AAKQSITSALMQGPEEAFDLGEAVAKVIYAPILRSY 193 Query: 160 LGQVGNGAKMKL-IVNMIMGSMMNAFSEGLVLADKSGLSSDTLLDIL 205 V A ++ + I +++ E + + G+ + D L Sbjct: 194 RLTVDQMALLEPGLSETICATLLQVMREAMDETVRRGVPKEAARDFL 240 >3G79-A nrPDB Length = 478 Score = 38.5 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 37/246 (15%), Positives = 74/246 (30%), Gaps = 53/246 (21%) Query: 2 EVGFLGLGIMGKAMS----------------MNLLKNGFKVTVWNR--TLSKCDE----- 38 ++G LG+G +G + N +G+K+ + NR + K +E Sbjct: 20 KIGVLGMGYVGIPAAVLFADAPCFEKVLGFQRNSKSSGYKIEMLNRGESPLKGEEPGLEE 79 Query: 39 ----LVEHGASVCESPAEVIKKCKYTIAMLSDPCAAL--------SVVFDKGGVLEQICE 86 +V+ G C I + + P A +++ V + + Sbjct: 80 LIGKVVKAGKFECTPDFSRISELDAVTLAIQTPFANPKDLEPDFSALIDGIRNVGKYLKP 139 Query: 87 GKGYIDMSTVDAETSLKINEAITG------KGGRF--VEGP--VSGSKKPAEDGQLIILA 136 G + ST+ T+ + + I G F P V + + + Sbjct: 140 GMLVVLESTITPGTTEGMAKQILEEESGLKAGEDFALAHAPERVMVGRLLKNIREHDRIV 199 Query: 137 AG-----DKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMMNAFSEGLVLA 191 G K E P V + + K N + A ++ + Sbjct: 200 GGIDEASTKRAVELYSPVLTV--GQVIPMSAT-AAEVTKTAENTFRDLQIAAINQLALYC 256 Query: 192 DKSGLS 197 + G++ Sbjct: 257 EAMGIN 262 >5TSD-A nrPDB Length = 322 Score = 38.5 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 17/68 (25%), Positives = 27/68 (39%), Gaps = 3/68 (4%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62 VG +GLGI+G+ L GF V W+RT + + A + + K + Sbjct: 145 VGVMGLGILGQDAVAKLKVMGFNVIGWSRTRKTIEGVETFDAGELD---RFLAKTDILVG 201 Query: 63 MLSDPCAA 70 +L Sbjct: 202 LLPLTPET 209 >1GDH-A nrPDB Length = 320 Score = 38.2 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 15/129 (11%), Positives = 46/129 (35%), Gaps = 2/129 (1%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62 +G G G +G+A++ + ++ + + + A+ +S ++ + Sbjct: 149 LGIYGFGSIGQALAKRAQGFDMDIDYFDTHRASSSDEASYQATFHDSLDSLLSVSQ--FF 206 Query: 63 MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSG 122 L+ P + F ++ + +G ++ + D + + A+ + V Sbjct: 207 SLNAPSTPETRYFFNKATIKSLPQGAIVVNTARGDLVDNELVVAALEAGRLAYAGFDVFA 266 Query: 123 SKKPAEDGQ 131 + +G Sbjct: 267 GEPNINEGY 275 >1ZEJ-A nrPDB Length = 293 Score = 38.2 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 19/123 (15%), Positives = 40/123 (32%), Gaps = 5/123 (4%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60 M+V +G G+MG+ +++ + +V + + + + E S E + Sbjct: 13 MKVFVIGAGLMGRGIAIAIASK-HEVVLQDVSEKALEAAREQIPEELLSKIEFTTTLEKV 71 Query: 61 IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITG----KGGRFV 116 A + K VL ++ S + I E + G ++ Sbjct: 72 KDCDIVMEAVFEDLNTKVEVLREVERLTNAPLCSNTSVISVDDIAERLDSPSRFLGVHWM 131 Query: 117 EGP 119 P Sbjct: 132 NPP 134 >4A7P-A nrPDB Length = 446 Score = 38.2 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 41/313 (13%), Positives = 82/313 (26%), Gaps = 52/313 (16%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCD---------------ELVEHGAS 45 + + +G G +G G +V ++ K + LV Sbjct: 9 VRIAMIGTGYVGLVSGACFSDFGHEVVCVDKDARKIELLHQNVMPIYEPGLDALVASNVK 68 Query: 46 VCE-----SPAEVIKKCKYTIAMLSDP-------CAALSVVFDKGGVLEQICEGKGYIDM 93 AE +K + P V + E + + + Sbjct: 69 AGRLSFTTDLAEGVKDADAVFIAVGTPSRRGDGHADLSYVFAAAREIAENLTKPSVIVTK 128 Query: 94 STVDAETSLKINEAITGKGGRFVEGPVSGSKKPAEDGQLI-------ILAAGDKALF--- 143 STV T ++ I V + + +G I + G + F Sbjct: 129 STVPVGTGDEVERIIAEVAPN-SGAKVVSNPEFLREGAAIEDFKRPDRVVVGTEDEFARQ 187 Query: 144 ---EESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMMNAFSEGLVLADKSGLSSDT 200 E P + G+ +K N + + +E L ++ G Sbjct: 188 VMREIYRPLSLNQSAPVLFTGRR-TSELIKYAANAFLAVKITFINEIADLCEQVGADVQE 246 Query: 201 LLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDMRLALALGDENAVSMPVAAAA 260 + + + F G P + KD + +N + + A Sbjct: 247 VSRGIGMDNRIGGKFLHAG---------PGYGGSCFPKDTLALMKTAADNETPLRIVEAT 297 Query: 261 NEAFK-KARSLGL 272 + + R++G Sbjct: 298 VQVNDARKRAMGR 310 >5C5I-A nrPDB Length = 316 Score = 38.2 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 23/108 (21%), Positives = 46/108 (42%), Gaps = 4/108 (3%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62 VG LGLG +G A ++ L GF V W+R+ + + H E+ ++ + + + Sbjct: 143 VGVLGLGELGAAAALRLRDAGFDVHGWSRSPKEIAGVTCHAGE--ETLERMLGQVEILVC 200 Query: 63 MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITG 110 +L ++ + L + EG ++ + S + EA+ Sbjct: 201 LLPLTGETRGLLDARR--LACLPEGAQIVNFARGPILDSAALIEALDS 246 >2AHR-A nrPDB Length = 259 Score = 37.8 bits (86), Expect = 0.005, Method: Composition-based stats. Identities = 33/217 (15%), Positives = 73/217 (33%), Gaps = 21/217 (9%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGAS-VCESPAEVIKKCKY 59 M++G +G+G M A+ L + ++ + +L + E+ E A S ++I + Sbjct: 4 MKIGIIGVGKMASAIIKGLKQTPHELIISGSSLERSKEIAEQLALPYAMSHQDLIDQVDL 63 Query: 60 TIAMLSDPCAALSVVFDK---GGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFV 116 I + V + + G ++T + L + + + + Sbjct: 64 VILGIK--PQLFETVLKPLHFKQPIISMAAGISLQRLATFVGQD-LPLLRIMPNMNAQIL 120 Query: 117 EGPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMI 176 + A G ++ + L D G +F + + L + Sbjct: 121 QS------STALTGNALV----SQELQARVRDLTDSFGS-TFDISEKDFDTFTALAGSSP 169 Query: 177 MGSMMNAFSEGLVLAD-KSGLSSDTLLDILDLGAMTN 212 + F E L A K+G+ L+I+ + + Sbjct: 170 AYIYL--FIEALAKAGVKNGIPKAKALEIVTQTVLAS 204 >1J49-A nrPDB Length = 333 Score = 37.8 bits (86), Expect = 0.006, Method: Composition-based stats. Identities = 17/92 (18%), Positives = 41/92 (44%), Gaps = 5/92 (5%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62 VG +G G +G+ + G KV ++ + EL + G +S ++ K+ Sbjct: 149 VGVVGTGHIGQVFMQIMEGFGAKVITYDIFRNP--ELEKKGYY-VDSLDDLYKQADVISL 205 Query: 63 MLSDPCAALSVVFDKGGVLEQICEGKGYIDMS 94 + D A + ++ D+ + ++ + +++S Sbjct: 206 HVPDVPANVHMINDES--IAKMKQDVVIVNVS 235 >4ZGS-A nrPDB Length = 386 Score = 37.8 bits (86), Expect = 0.006, Method: Composition-based stats. Identities = 17/108 (15%), Positives = 41/108 (37%), Gaps = 5/108 (4%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62 VG +G G +G+ + L G KV ++ + + G S E++ Sbjct: 181 VGVVGTGAIGQQAARILKGIGCKVFAYDIKPNPA--VEAMGIPYV-SLDELLAMSDIVTL 237 Query: 63 MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITG 110 + ++ + ++++ +G I++S S + +A+ Sbjct: 238 HCPLLPSTRQLINKES--IQKMKKGVMLINVSRGGLIDSAALFDALES 283 >4BVA-A nrPDB Length = 335 Score = 37.8 bits (86), Expect = 0.006, Method: Composition-based stats. Identities = 23/139 (16%), Positives = 49/139 (35%), Gaps = 20/139 (14%) Query: 25 KVTVWNRTLSKCDELVE--HG-ASVCESPAEVIKKCKYTIAMLSDPCAALSVVFDKGGVL 81 +V +WNRT ++ G VC S E + I + A ++F Sbjct: 184 EVRMWNRTRENAEKFASTVQGDVRVCSSVQEAVTGADVIITV---TMATEPILFG----- 235 Query: 82 EQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSGSKKPAEDGQLIILAAGDKA 141 E + G +I+ ++++ + + +V+ ++ A +L +G Sbjct: 236 EWVKPG-AHINAVGASRPDWRELDDELMRQAVLYVDS-----REAALKESGDVLLSG-AD 288 Query: 142 LFEESIPAFDVLGKRSFYL 160 +F E G + + Sbjct: 289 IFAELGEVIS--GAKPAHC 305 >6HRD-A nrPDB Length = 317 Score = 37.4 bits (85), Expect = 0.007, Method: Composition-based stats. Identities = 15/61 (24%), Positives = 26/61 (42%), Gaps = 5/61 (8%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHG-ASVCESPAEVIKKCKY 59 VG +G G MG ++ + G +VTV+ + L+ G + +S + K Sbjct: 26 QRVGVVGAGQMGSGIAEVSARAGVEVTVF----EPAEALITAGRNRIVKSLERAVSAGKV 81 Query: 60 T 60 T Sbjct: 82 T 82 >5N2I-A nrPDB Length = 232 Score = 37.4 bits (85), Expect = 0.008, Method: Composition-based stats. Identities = 14/110 (12%), Positives = 30/110 (27%), Gaps = 9/110 (8%) Query: 7 GLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCE----SPAEVIKKCKYTIA 62 G G G+ ++ G +V + +R+ + + A + I Sbjct: 27 GTGDQGRGLARRFAMAGHEVILGSRSAERAQAVAAELGEGLPVRGMDNAGAAEAGDVVIV 86 Query: 63 MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKG 112 + +++ VL GK +D +G Sbjct: 87 AVPWDGH-RALLESLKDVLA----GKIVVDCVNPLGFDKRGAYALPVEEG 131 >4B3J-A nrPDB Length = 736 Score = 37.4 bits (85), Expect = 0.008, Method: Composition-based stats. Identities = 18/89 (20%), Positives = 31/89 (34%), Gaps = 7/89 (7%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKC-------DELVEHGASVCESPAEVI 54 +G LG G+MG ++ K G++V + + +L ++L + E Sbjct: 343 RIGVLGAGMMGAGIAYVSAKAGYEVVLKDVSLEAAAKGKGYSEKLEAKALERGRTTQERS 402 Query: 55 KKCKYTIAMLSDPCAALSVVFDKGGVLEQ 83 I +D V F V E Sbjct: 403 DALLARITPTADAADFKGVDFVIEAVFEN 431 >1HL3-A nrPDB Length = 358 Score = 37.0 bits (84), Expect = 0.009, Method: Composition-based stats. Identities = 17/108 (15%), Positives = 41/108 (37%), Gaps = 3/108 (2%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62 +G +GLG +G+A+++ GF V ++ LS E G + +++ Sbjct: 174 LGIIGLGRVGQAVALRAKAFGFNVLFYDPYLSDGIE-RALGLQRVSTLQDLLFHSD--CV 230 Query: 63 MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITG 110 L + ++Q+ +G ++ + + +A+ Sbjct: 231 TLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQALKE 278 >5E4R-A nrPDB Length = 490 Score = 37.0 bits (84), Expect = 0.010, Method: Composition-based stats. Identities = 37/261 (14%), Positives = 74/261 (28%), Gaps = 47/261 (18%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESP---------AEV 53 + LG G G+A ++NL +G V V L G S + + Sbjct: 20 IAILGYGSQGRAWALNLRDSGLNVVV---------GLERQGDSWRRAIDDGFKPMYTKDA 70 Query: 54 IKKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGK--GYIDMSTVDAETSLKINEAITGK 111 + + ++ D + V + + +G + + KI E Sbjct: 71 VAIADIIVFLVPD---MVQKSLWLNSVKDFMKKGADLVFAHGFNIHF----KIIEPPKDS 123 Query: 112 GGRFVEGPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKL 171 ++ P S + + G V + Y G + L Sbjct: 124 DV-YMIAPKSPGPIVRRSYE---MGGG-------------VPALVAVYQNVSGEALQKAL 166 Query: 172 IVNMIMGSMMNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAF 231 + +G E K +D + + L + K ++ + Y P Sbjct: 167 AIAKGIGCARAGVIESTF---KEETETDLFGEQVILVGGIMELIKASFETLVEEGYQPEV 223 Query: 232 PLKHQQKDMRLALALGDENAV 252 +++L + L E + Sbjct: 224 AYFETVNELKLIVDLIYEKGL 244 >2QYS-A nrPDB Length = 318 Score = 37.0 bits (84), Expect = 0.010, Method: Composition-based stats. Identities = 23/79 (29%), Positives = 30/79 (37%), Gaps = 11/79 (13%) Query: 5 FLGLGIMGKAMSMNLLKNGFKVTVWNR-TLSKC---DELVEHGASVC-------ESPAEV 53 F G G +G M LK G V+ R SK DE GA + E E+ Sbjct: 17 FGGTGYIGNHMVKGSLKLGHPTYVFTRPNSSKTTLLDEFQSLGAIIVKGELDEHEKLVEL 76 Query: 54 IKKCKYTIAMLSDPCAALS 72 +KK I+ L+ P Sbjct: 77 MKKVDVVISALAFPQILDQ 95 >1YQG-A nrPDB Length = 263 Score = 37.0 bits (84), Expect = 0.011, Method: Composition-based stats. Identities = 42/222 (18%), Positives = 79/222 (35%), Gaps = 13/222 (5%) Query: 1 MEVGFLGLGIMGKAMSMNLLKN-GFKVTVWNRTLSKCDELVEH-GASVCESPAEVIKKCK 58 M V FLG G M A++ L+K G+++ + NR K + L + G + E+ Sbjct: 1 MNVYFLGGGNMAAAVAGGLVKQGGYRIYIANRGAEKRERLEKELGVETSATLPELHSDDV 60 Query: 59 YTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEG 118 +A+ A G L + + + +I + G+ + Sbjct: 61 LILAVKPQDMEAACKNIRTNGALVLSVAAGLSVGTLSRYLGGTRRIVRVMPNTPGK-IGL 119 Query: 119 PVSGSKKPAEDGQLIILAAGDKALFEESIPAFDV---LGKRSFYLGQVG-NGAKMKLIVN 174 VSG AE + D+ + + + + + L G G +G+ + Sbjct: 120 GVSGMYAEAEVSET------DRRIADRIMKSVGLTVWLDDEEKMHGITGISGSGPAYVFY 173 Query: 175 MIMGSMMNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFK 216 ++ A +G +A+ LS T + L T F+ Sbjct: 174 LLDALQNAAIRQGFDMAEARALSLATFKGAVALAEQTGEDFE 215 >2CUK-A nrPDB Length = 311 Score = 36.6 bits (83), Expect = 0.013, Method: Composition-based stats. Identities = 18/106 (16%), Positives = 38/106 (35%), Gaps = 9/106 (8%) Query: 6 LGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIAMLS 65 +G+G +G+A++ L G +V RT L S E++K+ Sbjct: 150 VGMGRIGQAVAKRALAFGMRVVYHARTP---KPL----PYPFLSLEELLKEADVVSLHTP 202 Query: 66 DPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGK 111 ++ + L + G ++ + + + EA+ G Sbjct: 203 LTPETHRLLNRER--LFAMKRGAILLNTARGALVDTEALVEALRGH 246 >1ZCJ-A nrPDB Length = 463 Score = 36.6 bits (83), Expect = 0.013, Method: Composition-based stats. Identities = 20/93 (21%), Positives = 36/93 (38%), Gaps = 11/93 (11%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDEL-------VEHGASVCESPAEVIK 55 VG LGLG MG+ ++++ + G V + D +E AS + Sbjct: 40 VGVLGLGTMGRGIAISFARVGISVVAVESDPKQLDAAKKIITFTLEKEASRAHQNGQASA 99 Query: 56 KCKYTIAM----LSDPCAALSVVFDKGGVLEQI 84 K K + LS + VF+ + +++ Sbjct: 100 KPKLRFSSSTKELSTVDLVVEAVFEDMNLKKKV 132 >3HDH-A nrPDB Length = 302 Score = 36.6 bits (83), Expect = 0.013, Method: Composition-based stats. Identities = 23/95 (24%), Positives = 40/95 (42%), Gaps = 9/95 (9%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRT---LSKCDELVEHGASV------CESPAE 52 V +G G+MG ++ G V + ++T L+K + +E E+P Sbjct: 17 HVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENPKA 76 Query: 53 VIKKCKYTIAMLSDPCAALSVVFDKGGVLEQICEG 87 + + T++ +S A SVV V+E I E Sbjct: 77 GDEFVEKTLSSISTSTDAASVVHSTDLVVEAIVEN 111 >6ABJ-A nrPDB Length = 345 Score = 36.6 bits (83), Expect = 0.013, Method: Composition-based stats. Identities = 12/116 (10%), Positives = 36/116 (31%), Gaps = 5/116 (4%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61 VG +G G +G+ + + G ++ ++ + + G ++ + Sbjct: 162 RVGVIGTGQIGETFARIMAGFGCELLAYDPYPNP--RIQALGGRYLA-LDALLAESDIVS 218 Query: 62 AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVE 117 ++ + L + G I+ + + EA+ ++ Sbjct: 219 LHCPLTADTRHLIDAQR--LATMKPGAMLINTGRGALVNAAALIEALKSGQLGYLG 272 >4XDZ-A nrPDB Length = 343 Score = 36.6 bits (83), Expect = 0.014, Method: Composition-based stats. Identities = 35/259 (13%), Positives = 72/259 (27%), Gaps = 43/259 (16%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESP---------AEV 53 + LG G G+A ++NL +G V V L G S + + Sbjct: 20 IAILGYGSQGRAWALNLRDSGLNVVV---------GLERQGDSWRRAIDDGFKPMYTKDA 70 Query: 54 IKKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGG 113 + + ++ D + +++ + + KI E Sbjct: 71 VAIADIIVFLVPDMVQKSLWLNSVKDFMKK-GADLVFAHGFNIHF----KIIEPPKDSDV 125 Query: 114 RFVEGPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIV 173 ++ P S + + G V + Y G + L + Sbjct: 126 -YMIAPKSPGPIVRRSYE---MGGG-------------VPALVAVYQNVSGEALQKALAI 168 Query: 174 NMIMGSMMNAFSEGLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPL 233 +G E K +D + + L + K ++ + Y P Sbjct: 169 AKGIGCARAGVIESTF---KEETETDLFGEQVILVGGIMELIKASFETLVEEGYQPEVAY 225 Query: 234 KHQQKDMRLALALGDENAV 252 +++L + L E + Sbjct: 226 FETVNELKLIVDLIYEKGL 244 >4N7R-A nrPDB Length = 472 Score = 36.2 bits (82), Expect = 0.015, Method: Composition-based stats. Identities = 16/99 (16%), Positives = 33/99 (33%), Gaps = 9/99 (9%) Query: 5 FLGLGIMGKAMSMNLLKNGFK-VTVWNRTLSKCDELVEHGASV------CESPAEVIKKC 57 +G G MGK + +L+ G V V NR+ + + E + + + Sbjct: 212 VIGAGKMGKLVIKHLMAKGCTKVVVVNRSEERVSAIREEMPGIEIIYRPLDEMLACASEA 271 Query: 58 KYTIAML--SDPCAALSVVFDKGGVLEQICEGKGYIDMS 94 P V + ++ + ++D+S Sbjct: 272 DVVFTSTASETPLFLKEHVENLPQASPEVGGLRHFVDIS 310 >1F14-A nrPDB Length = 310 Score = 36.2 bits (82), Expect = 0.015, Method: Composition-based stats. Identities = 33/241 (13%), Positives = 70/241 (29%), Gaps = 48/241 (19%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRT--------------------------LSK 35 V +G G+MG ++ G V + ++T Sbjct: 17 HVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENPKA 76 Query: 36 CDELVEHGASVCESPAEVIKKC---KYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYID 92 DE VE S + + + + + + +F + + + E + Sbjct: 77 GDECVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKR--LDKFAAEHTIFAS 134 Query: 93 MSTVDAETSLKIN--EAITGKGGRFVE-GPVSGSKKPAEDGQLIILAAGDKALFEESIPA 149 ++ TS+ G F PV + + + FE + Sbjct: 135 NTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMT------SQKTFESLVDF 188 Query: 150 FDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMMNAFSEGLVLADKSGLSSDTLLDILDLGA 209 LGK ++ +++ +M E + L ++ S + + + LGA Sbjct: 189 SKALGKHPVSCKDTPG----FIVNRLLVPYLM----EAIRLYERGDASKEDIDTAMKLGA 240 Query: 210 M 210 Sbjct: 241 G 241 >3ZWA-A nrPDB Length = 742 Score = 36.2 bits (82), Expect = 0.016, Method: Composition-based stats. Identities = 20/93 (21%), Positives = 36/93 (38%), Gaps = 11/93 (11%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDEL-------VEHGASVCESPAEVIK 55 VG LGLG MG+ ++++ + G V + D +E AS + Sbjct: 319 VGVLGLGTMGRGIAISFARVGISVVAVESDPKQLDAAKKIITFTLEKEASRAHQNGQASA 378 Query: 56 KCKYTIAM----LSDPCAALSVVFDKGGVLEQI 84 K K + LS + VF+ + +++ Sbjct: 379 KPKLRFSSSTKELSTVDLVVEAVFEDMNLKKKV 411 >2VHY-A nrPDB Length = 377 Score = 35.8 bits (81), Expect = 0.020, Method: Composition-based stats. Identities = 17/98 (17%), Positives = 31/98 (31%), Gaps = 8/98 (8%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHG-------ASVCESPAEVI 54 +V +G G G + G VTV + + K +L S + Sbjct: 170 DVVVIGAGTAGYNAARIANGMGATVTVLDINIDKLRQLDAEFCGRIHTRYSSAYELEGAV 229 Query: 55 KKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYID 92 K+ I + P A + ++ + G +D Sbjct: 230 KRADLVIGAVLVPGA-KAPKLVSNSLVAHMKPGAVLVD 266 >4J90-A nrPDB Length = 222 Score = 35.8 bits (81), Expect = 0.021, Method: Composition-based stats. Identities = 9/59 (15%), Positives = 22/59 (37%), Gaps = 2/59 (3%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60 + +GLG G ++ L + G +V + K + + + A ++ + Sbjct: 8 QFAVIGLGRFGGSICKELHRMGHEVLAVDINEEKVNAYASY--ATHAVIANATEENELL 64 >2RCY-A nrPDB Length = 262 Score = 35.5 bits (80), Expect = 0.028, Method: Composition-based stats. Identities = 22/88 (25%), Positives = 36/88 (40%), Gaps = 17/88 (19%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASV-------CESPAEV 53 +++GF+GLG MG A++ + N + K + L +G S S E+ Sbjct: 5 IKLGFMGLGQMGSALAHGIA---------NANIIKKENLFYYGPSKKNTTLNYMSSNEEL 55 Query: 54 IKKCKYTIAMLSDPCAALSVVFDKGGVL 81 + C I P A SV+ + L Sbjct: 56 ARHCD-IIVCAVKPDIAGSVLNNIKPYL 82 >6IUM-B nrPDB Length = 701 Score = 35.5 bits (80), Expect = 0.029, Method: Composition-based stats. Identities = 17/55 (30%), Positives = 24/55 (43%), Gaps = 4/55 (7%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKK 56 +V +G G MG +SMN L G VT+ L E ++ G + E K Sbjct: 294 KVAVIGAGTMGGGISMNFLNAGIPVTI----LETKQEALDRGVGIIRKNYENSAK 344 >3K96-A nrPDB Length = 356 Score = 35.5 bits (80), Expect = 0.032, Method: Composition-based stats. Identities = 13/43 (30%), Positives = 21/43 (48%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGA 44 + LG G G A+++ L + G KV +W+ DE+ G Sbjct: 31 PIAILGAGSWGTALALVLARKGQKVRLWSYESDHVDEMQAEGV 73 >3BA1-A nrPDB Length = 333 Score = 35.1 bits (79), Expect = 0.033, Method: Composition-based stats. Identities = 24/169 (14%), Positives = 50/169 (29%), Gaps = 31/169 (18%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61 VG +GLG +G A++ ++ ++R+ +G S E+ + Sbjct: 166 RVGIIGLGRIGLAVAERAEAFDCPISYFSRSKKPNTNYTYYG-----SVVELASNSDILV 220 Query: 62 AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121 ++ + V++ + I++ ++ A+ V Sbjct: 221 VACPLTPETTHIINRE--VIDALGPKGVLINIGRGPHVDEPELVSAL-----------VE 267 Query: 122 GSKKPAEDGQLIILAAGDKALFEESIPAFDVLGK--RSFYLGQVGNGAK 168 G A +FE + L L VG+G Sbjct: 268 GRLGGAGL-----------DVFEREPEVPEKLFGLENVVLLPHVGSGTV 305 >1CER-O nrPDB Length = 331 Score = 35.1 bits (79), Expect = 0.033, Method: Composition-based stats. Identities = 34/165 (20%), Positives = 55/165 (33%), Gaps = 16/165 (9%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWN-RTLSKC-DELVEHGASVCESPAEVIKKCK 58 M+VG G G +G+ + L G +V + N T +K L+++ + P EV + Sbjct: 1 MKVGINGFGRIGRQVFRILHSRGVEVALINDLTDNKTLAHLLKYDSIYHRFPGEVAYDDQ 60 Query: 59 YTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGR--FV 116 Y D A + + G G + ST + K +A G + + Sbjct: 61 YLYV---DGKAIRATAVKDPKEIPWAEAGVGVVIESTGVFTDADK-AKAHLEGGAKKVII 116 Query: 117 EGP--------VSGSKKPAEDGQLIILAAGDKALFEESIPAFDVL 153 P V G A D + + P VL Sbjct: 117 TAPAKGEDITIVMGVNHEAYDPSRHHIISNASCTTNSLAPVMKVL 161 >4MIE-A nrPDB Length = 351 Score = 35.1 bits (79), Expect = 0.034, Method: Composition-based stats. Identities = 23/153 (15%), Positives = 51/153 (33%), Gaps = 22/153 (14%) Query: 1 MEVGFLGLGIMGKAMS---MNLLKNGFKVTVWNRTLSKCDELVE---HGASVCESPAEVI 54 ++VG +G G MG+A N+L V V + + V A V ++ Sbjct: 15 VKVGVIGTGAMGRAHIDRLTNVLTGAEVVAVTDIDHEAAEAAVRDFHLNAKVYPDDTSLL 74 Query: 55 KKCKY-TIAMLSDPCAALSVV----------FDKGGVLEQICEGKGYIDMSTVDAETSLK 103 + + ++S A + V F + + + K +D ++ ++ Sbjct: 75 QDPDIDAVFVVSFGGAHEATVLKALDTDKFIFTEKPLATTLEGAKRIVDKELTKSKKVIQ 134 Query: 104 IN-EAITGKGGRF----VEGPVSGSKKPAEDGQ 131 + +G R ++ + G+ Sbjct: 135 VGFMRRYDQGIRALKEKLDTGIIGAPLVVRASH 167 >2EV9-A nrPDB Length = 263 Score = 35.1 bits (79), Expect = 0.037, Method: Composition-based stats. Identities = 18/69 (26%), Positives = 28/69 (40%), Gaps = 7/69 (10%) Query: 19 LLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI----AMLSDPCA--ALS 72 L + G +V VWNRT + L E P E ++ + + L DP A + Sbjct: 135 LREAGLEVWVWNRTPQRALALAEEFGLRA-VPLEKAREARLLVNATRVGLEDPSASPLPA 193 Query: 73 VVFDKGGVL 81 +F + G Sbjct: 194 ELFPEEGAA 202 >4DYD-A nrPDB Length = 283 Score = 35.1 bits (79), Expect = 0.039, Method: Composition-based stats. Identities = 34/241 (14%), Positives = 74/241 (30%), Gaps = 52/241 (21%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEH-------------------- 42 V LG G++G ++ +GF VT ++ D + Sbjct: 7 VTVLGTGVLGSQIAFQTAFHGFAVTAYDINTDALDAAKKRFEGLAAVYEKEVAGAADGAA 66 Query: 43 -----GASVCESPAEVIKKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYI-DMSTV 96 G + A+ +K I + + ++ K G L + + ST+ Sbjct: 67 QKALGGIRYSDDLAQAVKDADLVIEAVPESLDLKRDIYTKLGELAPAK--TIFATNSSTL 124 Query: 97 DAET----SLKINEAITGKGGRFV----EGPVSGSKKPAEDGQLIILAAGDKALFEESIP 148 + + ++ + V V G+ K D ++++ + Sbjct: 125 LPSDLVGYTGRGDKFLALHFANHVWVNNTAEVMGTTKT------------DPEVYQQVVE 172 Query: 149 AFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMMNAFSEGLVLADKSGLSSDTLLDILDLG 208 +G L + G ++N ++ +++A +E LV + D I Sbjct: 173 FASAIGMVPIELKKEKAG----YVLNSLLVPLLDAAAELLVDGIADPETIDKTWRIGTGA 228 Query: 209 A 209 Sbjct: 229 P 229 >1QP8-A nrPDB Length = 303 Score = 35.1 bits (79), Expect = 0.041, Method: Composition-based stats. Identities = 18/111 (16%), Positives = 41/111 (36%), Gaps = 10/111 (9%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGA-SVCESPAEVIKKCKYT 60 +V LGLG +G + L G +V ++RT + G S E +++ + Sbjct: 126 KVAVLGLGEIGTRVGKILAALGAQVRGFSRTP-------KEGPWRFTNSLEEALREARAA 178 Query: 61 IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGK 111 + L +V + L + E ++++ + + + + Sbjct: 179 VCALPLNKHTRGLVKYQH--LALMAEDAVFVNVGRAEVLDRDGVLRILKER 227 >4ZCC-A nrPDB Length = 336 Score = 35.1 bits (79), Expect = 0.042, Method: Composition-based stats. Identities = 7/34 (20%), Positives = 18/34 (52%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLS 34 + + +G GI G + + L G +V +++++ Sbjct: 3 VPIAIIGTGIAGLSAAQALTSAGHQVHLFDKSRG 36 >2YQ5-A nrPDB Length = 343 Score = 34.7 bits (78), Expect = 0.052, Method: Composition-based stats. Identities = 18/124 (14%), Positives = 49/124 (39%), Gaps = 13/124 (10%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKC-DELVEHGASVCESPAEVIKKCKY 59 + VG +G+G +G A++ G KV ++ + + + + V+K+ Sbjct: 149 LTVGLIGVGHIGSAVAEIFSAMGAKVIAYDVAYNPEFEPFLTY-----TDFDTVLKEADI 203 Query: 60 TIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAI-----TGKGGR 114 + +++ +K L+++ + I+ + + + + +A+ G G Sbjct: 204 VSLHTPLFPSTENMIGEKQ--LKEMKKSAYLINCARGELVDTGALIKALQDGEIAGAGLD 261 Query: 115 FVEG 118 + G Sbjct: 262 TLAG 265 >2HMT-A nrPDB Length = 144 Score = 34.3 bits (77), Expect = 0.055, Method: Composition-based stats. Identities = 9/59 (15%), Positives = 22/59 (37%), Gaps = 2/59 (3%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60 + +GLG G ++ L + G +V + K + + + A ++ + Sbjct: 8 QFAVIGLGRFGGSIVKELHRMGHEVLAVDINEEKVNAYASY--ATHAVIANATEENELL 64 >5BUT-A nrPDB Length = 288 Score = 34.3 bits (77), Expect = 0.059, Method: Composition-based stats. Identities = 9/59 (15%), Positives = 22/59 (37%), Gaps = 2/59 (3%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60 + +GLG G ++ L + G +V + K + + + A ++ + Sbjct: 8 QFAVIGLGRFGGSIVKELHRMGHEVLAVDINEEKVNAYASY--ATHAVIANATEENELL 64 Score = 34.3 bits (77), Expect = 0.059, Method: Composition-based stats. Identities = 9/59 (15%), Positives = 22/59 (37%), Gaps = 2/59 (3%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60 + +GLG G ++ L + G +V + K + + + A ++ + Sbjct: 150 QFAVIGLGRFGGSIVKELHRMGHEVLAVDINEEKVNAYASY--ATHAVIANATEENELL 206 >5VJ7-A nrPDB Length = 476 Score = 34.3 bits (77), Expect = 0.064, Method: Composition-based stats. Identities = 19/99 (19%), Positives = 42/99 (42%), Gaps = 2/99 (2%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61 +V +G G G + +L K G++VT++ L + ++ +G P E+++K + Sbjct: 156 KVAIIGAGPAGLTCAADLAKMGYEVTIYE-ALHQPGGVLTYGIPEFRLPKEILRKELKKL 214 Query: 62 AMLSDPCAALSVVFDKGGVLEQICEGK-GYIDMSTVDAE 99 ++L +V + E + E +I + Sbjct: 215 SLLGVEIKTDHIVGKTITIQELLQEYDAVFIGTGAGTPK 253 >5YEQ-A nrPDB Length = 340 Score = 34.3 bits (77), Expect = 0.068, Method: Composition-based stats. Identities = 18/66 (27%), Positives = 29/66 (43%), Gaps = 2/66 (3%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTV-WNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60 V LG G G+A ++NL +G KV+V R + + G + E ++ Sbjct: 19 RVAVLGYGSQGRAWALNLRDSGIKVSVGLEREGNSWKQAENDGFKPLRT-EEAVRNSDII 77 Query: 61 IAMLSD 66 I +L D Sbjct: 78 IFLLPD 83 >6IH4-A nrPDB Length = 338 Score = 34.3 bits (77), Expect = 0.069, Method: Composition-based stats. Identities = 20/112 (17%), Positives = 41/112 (36%), Gaps = 11/112 (9%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCE----SPAEVIKKCK 58 +G G+G +G+A++ L GF++ N L + E+++KC Sbjct: 148 LGIRGMGAVGRAIAQRL--AGFEM---NLLYCDEIPLNAEQEKAWHVQRVTLDELLEKCD 202 Query: 59 YTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITG 110 Y + M+ L ++ L ++ G I+ + A+ Sbjct: 203 YVVPMVPMAAETLHLIDATA--LAKMKTGSYLINACRGSVVDENAVIAALAS 252 >3KB6-A nrPDB Length = 334 Score = 33.9 bits (76), Expect = 0.092, Method: Composition-based stats. Identities = 20/107 (18%), Positives = 45/107 (42%), Gaps = 5/107 (4%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60 + +G +G G +G ++M L G KV ++ K ++L E G V S E++K+ Sbjct: 142 LTLGVIGTGRIGSRVAMYGLAFGMKVLCYDVV--KREDLKEKGC-VYTSLDELLKESDVI 198 Query: 61 IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEA 107 + ++ ++ + + +G I+ + + + A Sbjct: 199 SLHVPYTKETHHMINEER--ISLMKDGVYLINTARGKVVDTDALYRA 243 >3I83-A nrPDB Length = 320 Score = 33.9 bits (76), Expect = 0.093, Method: Composition-based stats. Identities = 44/305 (14%), Positives = 89/305 (29%), Gaps = 48/305 (15%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHG---------------AS 45 + + +G G +G L K G V+V + S + + G A+ Sbjct: 3 LNILVIGTGAIGSFYGALLAKTGHCVSV--VSRSDYETVKAKGIRIRSATLGDYTFRPAA 60 Query: 46 VCESPAEVIKKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYI-DMSTVDAETSLKI 104 V S AE+ K T+ + A V + V G I + ++ E + Sbjct: 61 VVRSAAELETKPDCTLLCIKVVEGADRVGLLRDAVAP--DTGIVLISNGIDIEPEVAAAF 118 Query: 105 NEAITGKGGRFVEGPVSGSKKPAEDGQLIIL----AAGDKALFEESIPAFDVLG------ 154 + G F+ + + ++ G + AF+ G Sbjct: 119 PDNEVISGLAFIGVTRTAPGEIWHQAYGRLMLGNYPGGVSERVKTLAAAFEEAGIDGIAT 178 Query: 155 -----KRSFYLGQVGNGAKMKLIVNMIMGSMMNAFSEGL---------VLADKSGLSSDT 200 R + ++ + + + EG +A +G Sbjct: 179 ENITTARWQKCVWNAAFNPLSVLSGGLDTLDILSTQEGFVRAIMQEIRAVAAANGHPLPE 238 Query: 201 LLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDMRLALALGDENAVSMPVAAAA 260 DI++ + SM + P++ + + A+ G V++P + Sbjct: 239 --DIVEKNVASTYKMPPYKTSMLV-DFEAGQPMETEVI-LGNAVRAGRRTRVAIPHLESV 294 Query: 261 NEAFK 265 K Sbjct: 295 YALMK 299 >6ACQ-A nrPDB Length = 302 Score = 33.5 bits (75), Expect = 0.097, Method: Composition-based stats. Identities = 36/234 (15%), Positives = 68/234 (29%), Gaps = 42/234 (17%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDE-----------LVEHGASVCESP 50 +V +G G MG ++ GF+V + + D LV+ G + Sbjct: 23 KVCVIGAGTMGSGIAQAFAAKGFEVVLRDIKDEFVDRGLDFINKNLSKLVKKGKIEEATK 82 Query: 51 AEV------------IKKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDA 98 E+ C I + +F + ++ + Sbjct: 83 VEILTRISGTVDLNMAADCDLVIEAAVERMDIKKQIFA--DLDNICKPETILASNTSSLS 140 Query: 99 ETSLKINEAITGK--GGRFVE-GPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGK 155 T + K G F PV + G + F+ +GK Sbjct: 141 ITEVASATKRPDKVIGMHFFNPAPVMKLVEVIR-GIAT-----SQETFDAVKETSIAIGK 194 Query: 156 RSFYLGQVGNGAKMKLIVNMIMGSMMNAFSEGLVLADKSGLSSDTLLDILDLGA 209 + + +VN I+ M+N E + + + S + + + LGA Sbjct: 195 DPVEVAEAPG-----FVVNRILIPMIN---EAVGILAEGIASVEDIDKAMKLGA 240 >2RIR-A nrPDB Length = 300 Score = 33.5 bits (75), Expect = 0.099, Method: Composition-based stats. Identities = 23/131 (17%), Positives = 41/131 (31%), Gaps = 15/131 (11%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVC--ESPAEVIKKCKY 59 +V LGLG G ++ G V V R+ + + E G + E +K Sbjct: 159 QVAVLGLGRTGMTIARTFAALGANVKVGARSSAHLARITEMGLVPFHTDELKEHVKDIDI 218 Query: 60 TIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGP 119 I + + VL + +D+++ T K E +G + + P Sbjct: 219 CINTIPS-------MILNQTVLSSMTPKTLILDLASRPGGTDFKYAE---KQGIKALLAP 268 Query: 120 VSGSKKPAEDG 130 Sbjct: 269 ---GLPGIVAP 276 >3KKJ-A nrPDB Length = 336 Score = 33.5 bits (75), Expect = 0.11, Method: Composition-based stats. Identities = 7/34 (20%), Positives = 18/34 (52%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLS 34 + + +G GI G + + L G +V +++++ Sbjct: 3 VPIAIIGTGIAGLSAAQALTAAGHQVHLFDKSRG 36 >5JFC-L nrPDB Length = 474 Score = 33.5 bits (75), Expect = 0.12, Method: Composition-based stats. Identities = 15/55 (27%), Positives = 27/55 (49%), Gaps = 1/55 (1%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKK 56 +V +G G G + +L K G++VT++ L+ +G P E++KK Sbjct: 156 KVAIIGAGPAGLTCAADLAKMGYEVTIYEALHQPGGVLI-YGIPEFRLPKEIVKK 209 >4LSW-A nrPDB Length = 318 Score = 33.1 bits (74), Expect = 0.13, Method: Composition-based stats. Identities = 16/107 (14%), Positives = 35/107 (32%), Gaps = 6/107 (5%) Query: 4 GFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIAM 63 G LGLG +G ++ L +++ + + E + + + Sbjct: 149 GVLGLGRIGFEVARRLAGFDMQISYSDIAPKSYAP----DWTFVEDAVTLARDVDFLFVT 204 Query: 64 LSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITG 110 L+ A +V V+E + I++S + A+ Sbjct: 205 LAASAATRHIVG--RDVIEALGPEGMLINISRASNIDEEALIAALAD 249 >4A5O-A nrPDB Length = 286 Score = 33.1 bits (74), Expect = 0.14, Method: Composition-based stats. Identities = 23/130 (17%), Positives = 41/130 (31%), Gaps = 28/130 (21%) Query: 1 MEVGFLGLGIM-GKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKY 59 M+ +G + G+ M++ LL G VTV +R A+ + + Sbjct: 162 MDAVVVGASNIVGRPMALELLLGGCTVTVTHRFT--------------RDLADHVSRADL 207 Query: 60 TIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINE---AITGKGGRFV 116 + P E I EG ID+ + + + + ++ Sbjct: 208 VVVAAGKPGLVKG---------EWIKEGAIVIDVGINRQADGRLVGDVEYEVAAQRASWI 258 Query: 117 EGPVSGSKKP 126 PV G P Sbjct: 259 -TPVPGGVGP 267 >3TWO-A nrPDB Length = 348 Score = 33.1 bits (74), Expect = 0.15, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 28/67 (41%), Gaps = 1/67 (1%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCES-PAEVIKKCKYT 60 +VG G G +G + G +V+V+ R K + + G + P + ++ + Sbjct: 179 KVGVAGFGGLGSMAVKYAVAMGAEVSVFARNEHKKQDALSMGVKHFYTDPKQCKEELDFI 238 Query: 61 IAMLSDP 67 I+ + Sbjct: 239 ISTIPTH 245 >3FR8-A nrPDB Length = 525 Score = 32.8 bits (73), Expect = 0.18, Method: Composition-based stats. Identities = 14/101 (13%), Positives = 33/101 (32%), Gaps = 17/101 (16%) Query: 2 EVGFLGLGIMGKAMSMNL------------LKNGFKVTVWNRTLSKCDELVEHGASVCES 49 ++G +G G G A + NL +K G + + ++ E ++ + Sbjct: 56 QIGVIGWGSQGPAQAQNLRDSLAEAKSDIVVKIGLRKGSKSFDEARAAGFTEESGTLGD- 114 Query: 50 PAEVIKKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGY 90 E + + ++SD A + + + Sbjct: 115 IWETVSGSDLVLLLISDAAQAD----NYEKIFSHMKPNSIL 151 >4A6N-B nrPDB Length = 398 Score = 32.8 bits (73), Expect = 0.21, Method: Composition-based stats. Identities = 11/35 (31%), Positives = 18/35 (51%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCD 37 V +G G +G M+ L +NG V+V+ R + Sbjct: 29 VAIIGGGPVGLTMAKLLQQNGIDVSVYERDNDREA 63 >1JAY-A nrPDB Length = 212 Score = 32.8 bits (73), Expect = 0.21, Method: Composition-based stats. Identities = 17/99 (17%), Positives = 32/99 (32%), Gaps = 13/99 (13%) Query: 1 MEVGFLG-LGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESP-------AE 52 M V LG G +GK +++ L G ++ V +R K + + + Sbjct: 1 MRVALLGGTGNLGKGLALRLATLGHEIVVGSRREEKAEAKAAEYRRIAGDASITGMKNED 60 Query: 53 VIKKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYI 91 + C + + D L+ I K + Sbjct: 61 AAEACDIAVLTIP-----WEHAIDTARDLKNILREKIVV 94 >2OME-A nrPDB Length = 336 Score = 32.4 bits (72), Expect = 0.22, Method: Composition-based stats. Identities = 15/108 (13%), Positives = 39/108 (36%), Gaps = 3/108 (2%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62 +G +G G G+A+++ GF V ++ L E G + +++ + Sbjct: 155 LGLIGFGRTGQAVAVRAKAFGFSVIFYDPYLQDGIE-RSLGVQRVYTLQDLLYQSD--CV 211 Query: 63 MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITG 110 L + ++Q+ +G ++ + + +A+ Sbjct: 212 SLHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVDEKALAQALKE 259 >6NRP-A nrPDB Length = 263 Score = 32.0 bits (71), Expect = 0.31, Method: Composition-based stats. Identities = 13/31 (41%), Positives = 17/31 (54%) Query: 12 GKAMSMNLLKNGFKVTVWNRTLSKCDELVEH 42 GKA+++ L K GF VTV R+ E V Sbjct: 37 GKAIALQLAKAGFDVTVHARSRQAEAEQVVQ 67 >3LK7-A nrPDB Length = 451 Score = 31.6 bits (70), Expect = 0.36, Method: Composition-based stats. Identities = 32/159 (20%), Positives = 55/159 (34%), Gaps = 28/159 (17%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTV-----WNRTLSKCDELVEHGASVC--ESPAEVI 54 +V LGL G+A + L K G VTV ++ + L+E G V P E++ Sbjct: 11 KVLVLGLARSGEAAARLLAKLGAIVTVNDGKPFDENPT-AQSLLEEGIKVVCGSHPLELL 69 Query: 55 KKCKYTIAMLSDP------CAALSVVFDKGGVLEQICEGKGY-------IDMSTVDAETS 101 + M+ +P + + VL ++ I S T+ Sbjct: 70 DED--FCYMIKNPGIPYNNPMVKKALEKQIPVLTEVELAYLVSESQLIGITGSNGKTTTT 127 Query: 102 LKINEAITGKG-----GRFVEGPVSGSKKPAEDGQLIIL 135 I E + G + P S + A D +++ Sbjct: 128 TMIAEVLNAGGQRGLLAGNIGFPASEVVQAANDKDTLVM 166 >5OES-A nrPDB Length = 483 Score = 31.6 bits (70), Expect = 0.37, Method: Composition-based stats. Identities = 18/89 (20%), Positives = 36/89 (40%), Gaps = 4/89 (4%) Query: 12 GKAMSMNLLKNGFKVTVWNRTLS-KCDELVEHG-ASVCESPAEVIKKCKYTIAMLSDPCA 69 G+A+++ + G+ + +N K L+E A C S + + K L+ P Sbjct: 270 GQAVAVIYFRAGYAPSDYNSESEWKARLLMEQSRAVKCPSISYHLAGSKKIQQELAKPNV 329 Query: 70 ALSVVFDKGGV--LEQICEGKGYIDMSTV 96 + +K + L + G +D S + Sbjct: 330 LERFLENKDDIAKLRKCFAGLWSLDESDI 358 >2EGG-A nrPDB Length = 297 Score = 31.6 bits (70), Expect = 0.38, Method: Composition-based stats. Identities = 16/91 (17%), Positives = 28/91 (30%), Gaps = 10/91 (10%) Query: 30 NRTLSKCDELVEHG------ASVCESPAEVIKKCKYTIAMLSDPCAALSVVFDKGGVLEQ 83 NRT+ K + LV G + + I S V LE+ Sbjct: 172 NRTVEKAERLVREGDERRSAYFSLAEAETRLAEYDIIINTTSVGMHPRVEVQPLS--LER 229 Query: 84 ICEGKGYIDMSTVDAETSLKINEAITGKGGR 114 + G D+ + + + + +G R Sbjct: 230 LRPGVIVSDIIY-NPLETKWL-KEAKARGAR 258 >4KUG-A nrPDB Length = 290 Score = 31.6 bits (70), Expect = 0.39, Method: Composition-based stats. Identities = 17/60 (28%), Positives = 30/60 (50%), Gaps = 5/60 (8%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHG-ASVCESPAEVIKKCKYT 60 +V LG G MG + G +V V + +E V+ G A++ +S ++++ K K T Sbjct: 3 KVFVLGAGTMGAGIVQAFAAKGCEVIVRDIK----EEFVDRGIATITKSLSKLVAKEKIT 58 >4CUK-A nrPDB Length = 338 Score = 31.6 bits (70), Expect = 0.42, Method: Composition-based stats. Identities = 17/117 (14%), Positives = 36/117 (30%), Gaps = 5/117 (4%) Query: 4 GFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIAM 63 G +G G +G A L G ++ ++ S ++ G + + + Sbjct: 148 GVIGTGKIGVAALRILKGFGMRLLAFDPYPSTAA--LDLGVEYVD-LQTLFAESDVISLH 204 Query: 64 LSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPV 120 ++ +Q+ G I+ S S EA+ + + V Sbjct: 205 CPLTPENYHLLN--HAAFDQMKNGVMIINTSRGALIDSQAAIEALKNQKIGSLGMDV 259 >1GEG-A nrPDB Length = 256 Score = 31.6 bits (70), Expect = 0.44, Method: Composition-based stats. Identities = 17/94 (18%), Positives = 33/94 (35%), Gaps = 14/94 (14%) Query: 12 GKAMSMNLLKNGFKVTV--WNRTLSKCDELVEHGASVCESPAEVIKKCKYTIAMLSDPCA 69 GKA+++ L+K+GF V + +N +K V + +SD Sbjct: 15 GKAIALRLVKDGFAVAIADYNDATAKA---------VASEINQAGGHAVAVKVDVSDRDQ 65 Query: 70 ALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLK 103 + V L ++ + V T ++ Sbjct: 66 VFAAVEQARKTLGGF---DVIVNNAGVAPSTPIE 96 >1A5Z-A nrPDB Length = 319 Score = 31.6 bits (70), Expect = 0.45, Method: Composition-based stats. Identities = 10/24 (41%), Positives = 16/24 (66%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGF 24 M++G +GLG +G + + LL GF Sbjct: 1 MKIGIVGLGRVGSSTAFALLMKGF 24 >5Y77-A nrPDB Length = 473 Score = 31.2 bits (69), Expect = 0.50, Method: Composition-based stats. Identities = 17/119 (14%), Positives = 40/119 (33%), Gaps = 7/119 (5%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHG----ASVCESPAEVIKKC 57 +V +G G+ G ++ L +NG++V ++ R E G ++ E A ++ Sbjct: 10 QVTIIGAGLAGTLVARLLARNGWQVNLFERRPDPRIETGARGRSINLALAERGAHALRLA 69 Query: 58 KYTIAMLSDPCAALSVVFDKGGVLEQICE---GKGYIDMSTVDAETSLKINEAITGKGG 113 +L++ + G + + S + + + G Sbjct: 70 GLEREVLAEAVMMRGRMVHVPGTPPNLQPYGRDDSEVIWSINRDRLNRILLDGAEAAGA 128 >4PRK-A nrPDB Length = 336 Score = 31.2 bits (69), Expect = 0.50, Method: Composition-based stats. Identities = 14/109 (12%), Positives = 37/109 (33%), Gaps = 6/109 (5%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62 +G +G+G +G A++ G KV ++ + V+K+ Sbjct: 149 IGLIGVGHIGSAVAQIFSAMGAKVLAYDVIYNP----EVEPYLTYADFDTVLKEADIISL 204 Query: 63 MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGK 111 + +++ K ++ I+ + + + + EA+ Sbjct: 205 HTPLLKSTENMIGKKQ--FAEMKNDAILINAARGELVDTAALIEALEKH 251 >3WNV-A nrPDB Length = 330 Score = 31.2 bits (69), Expect = 0.51, Method: Composition-based stats. Identities = 19/118 (16%), Positives = 41/118 (34%), Gaps = 5/118 (4%) Query: 16 SMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIAMLSDPCAALSVVF 75 + G + NR +K +E GA S E++ + L+ + ++ Sbjct: 170 ARRARAFGMNIIYHNR--NKLPPELEDGAKYV-SFDELLAQSDVFSLNLALNASTRHIIG 226 Query: 76 DKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSGSKKPAEDGQLI 133 +K L ++ +G ++ + + A+ V V ++ E G L Sbjct: 227 EKE--LAKMKDGVVIVNTARGALIDEKALVRALESGKVASVGLDVYENEPQVEPGLLN 282 >2EW2-A nrPDB Length = 316 Score = 31.2 bits (69), Expect = 0.52, Method: Composition-based stats. Identities = 44/306 (14%), Positives = 90/306 (29%), Gaps = 41/306 (13%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKY- 59 M++ G G MG + + L + G VT+ ++ + + + ++G + EV+ Sbjct: 4 MKIAIAGAGAMGSRLGIMLHQGGNDVTLIDQWPAHIEAIRKNGLIADFNGEEVVANLPIF 63 Query: 60 -------------TIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINE 106 I L+ ++ ++ + ++ + + + Sbjct: 64 SPEEIDHQNEQVDLIIALTKAQQLDAMFKAIQPMITEKTYVLCLLNGLGHEDVLEKYVPK 123 Query: 107 AITGKGGRFVEGPVSGS--KKPAEDGQL---IILAAGDKALFEESIPAFDVLGKRSFYLG 161 G + G K DG++ I +G K E + F G Y Sbjct: 124 ENILVGITMWTAGLEGPGRVKLLGDGEIELENIDPSGKKFALE-VVDVFQKAGLNPSYSS 182 Query: 162 QVGNGAKMKLIVNM-------IMGSMMNAFS-----EGL--VLADKSGLSSDTLLDILDL 207 V K VN I+ + F E L L + ++ LD Sbjct: 183 NVRYSIWRKACVNGTLNGLCTILDCNIAEFGALPVSESLVKTLISEFAAVAEKEAIYLDQ 242 Query: 208 GAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDM-------RLALALGDENAVSMPVAAAA 260 + + + P+ YP + + + G + V+ P A Sbjct: 243 AEVYTHIVQTYDPNGIGLHYPSMYQDLIKNHRLTEIDYINGAVWRKGQKYNVATPFCAML 302 Query: 261 NEAFKK 266 + Sbjct: 303 TQLVHG 308 >1NYT-A nrPDB Length = 271 Score = 31.2 bits (69), Expect = 0.52, Method: Composition-based stats. Identities = 13/48 (27%), Positives = 24/48 (50%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCE 48 + + +G G + + + LL VT+ NRT+S+ +EL + A Sbjct: 120 LRILLIGAGGASRGVLLPLLSLDCAVTITNRTVSRAEELAKLFAHTGS 167 >6C6P-A nrPDB Length = 458 Score = 31.2 bits (69), Expect = 0.55, Method: Composition-based stats. Identities = 16/41 (39%), Positives = 25/41 (60%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEH 42 EV +G G++G A++ L ++G KVTV R L + D +V Sbjct: 9 EVIIVGAGVLGSALAAVLSRDGRKVTVIERDLKEPDRIVGE 49 >4FQ8-A nrPDB Length = 271 Score = 31.2 bits (69), Expect = 0.57, Method: Composition-based stats. Identities = 23/106 (21%), Positives = 39/106 (36%), Gaps = 5/106 (4%) Query: 5 FLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIAML 64 LG G KA++ L K G +V+V NR+ D G P + I Sbjct: 123 ILGAGGSAKALACELKKQGLQVSVLNRSSRGLDFFQRLGCDCFMEPPK--SAFDLIIN-- 178 Query: 65 SDPCAALSVVFDKGGVLEQ-ICEGKGYIDMSTVDAETSLKINEAIT 109 + + + + VL+ EGK D++ L + + + Sbjct: 179 ATSASLHNELPLNKEVLKGYFKEGKLAYDLAAGFLTPFLSLAKELK 224 >3QY9-A nrPDB Length = 243 Score = 30.8 bits (68), Expect = 0.62, Method: Composition-based stats. Identities = 14/121 (11%), Positives = 36/121 (29%), Gaps = 13/121 (10%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFK-VTVWNRTLSKCDELVEHG----ASVCESPAEVIK 55 M++ +G G M + ++ + G + V V T ++ + + Sbjct: 4 MKILLIGYGAMNQRVARLAEEKGHEIVGVIENTPKATTPYQQYQHIADVKGADVAIDFSN 63 Query: 56 KC--------KYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEA 107 + + ++ + +K L Q +MS + + A Sbjct: 64 PNLLFPLLDEDFHLPLVVATTGEKEKLLNKLDELSQNMPVFFSANMSYGVHALTKILAAA 123 Query: 108 I 108 + Sbjct: 124 V 124 >4K28-A nrPDB Length = 269 Score = 30.8 bits (68), Expect = 0.66, Method: Composition-based stats. Identities = 18/129 (13%), Positives = 43/129 (33%), Gaps = 13/129 (10%) Query: 5 FLGLGIMGKAMSMNLLKNGF-KVTVWNRTLSKCD---ELVEHG--ASVCESPAEVIKKCK 58 +G G +G A++ L + G +T+ + + ++ EL+ +G + ++ Sbjct: 130 VIGCGGVGSAIAYALAEAGIASITLCDPSTARMGAVCELLGNGFPGLTVSTQFSGLEDFD 189 Query: 59 YTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEG 118 + + +L + D+ T E + +N R V Sbjct: 190 LVANASPVGMGTRAELPLSAALLATLQPDTLVADVVT-SPEITPLLNR------ARQVGC 242 Query: 119 PVSGSKKPA 127 + + A Sbjct: 243 RIQTGPEMA 251 >4HY3-A nrPDB Length = 365 Score = 30.8 bits (68), Expect = 0.67, Method: Composition-based stats. Identities = 19/109 (17%), Positives = 43/109 (39%), Gaps = 4/109 (3%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61 E+G +G G +GKA+ L ++ V++ L + ++E S +V+ K + Sbjct: 178 EIGIVGFGDLGKALRRVLSGFRARIRVFDPWLPRS--MLEENGVEPASLEDVLTKSDFIF 235 Query: 62 AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITG 110 + + + + + G +I +S D + A++ Sbjct: 236 VVAAVTSENKRFLGAEA--FSSMRRGAAFILLSRADVVDFDALMAAVSS 282 >3GT0-A nrPDB Length = 247 Score = 30.8 bits (68), Expect = 0.67, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 28/69 (40%), Gaps = 5/69 (7%) Query: 2 EVGFLGLGIMGKAMS-----MNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKK 56 ++GF+G G MG AM N++ + + T + + ++G + EV K Sbjct: 4 QIGFIGCGNMGMAMIGGMINKNIVSSNQIICSDLNTANLKNASEKYGLTTTTDNNEVAKN 63 Query: 57 CKYTIAMLS 65 I + Sbjct: 64 ADILILSIK 72 >4FSH-A nrPDB Length = 271 Score = 30.8 bits (68), Expect = 0.68, Method: Composition-based stats. Identities = 19/83 (22%), Positives = 33/83 (39%), Gaps = 8/83 (9%) Query: 5 FLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIAML 64 LG G KA++ L K G KV+V NR+ D G P + I Sbjct: 123 ILGSGGSAKALACGLKKQGLKVSVLNRSPRGLDFFQRLGCDCFMEPPK--SAFDLII--- 177 Query: 65 SDPCAALSVVFDKGGVLEQICEG 87 A + + ++ + +++ +G Sbjct: 178 ---NATSASLNNELPLNKEVLKG 197 >4OH1-A nrPDB Length = 351 Score = 30.8 bits (68), Expect = 0.69, Method: Composition-based stats. Identities = 21/115 (18%), Positives = 39/115 (33%), Gaps = 26/115 (22%) Query: 7 GLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAE-------------- 52 GLG+M ++ L +TV++ K + +E+GA + AE Sbjct: 184 GLGMMLVQLAR--LAGASTITVFDIVPEKLELALENGADYALNSAEEGVAERAIELAGGR 241 Query: 53 ---------VIKKCKYTIAMLS-DPCAALSVVFDKGGVLEQICEGKGYIDMSTVD 97 K + +L+ D A ++ K +L + Y D + Sbjct: 242 YDCVLEGTGATAAAKLGLQLLARDGDAVYFAMYGKDPILPVNLQSDLYWDQKHIH 296 >1VC2-A nrPDB Length = 331 Score = 30.4 bits (67), Expect = 0.81, Method: Composition-based stats. Identities = 23/122 (18%), Positives = 41/122 (33%), Gaps = 6/122 (4%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWN-RTLSKCDELVEHGASVCESPAEVIKKCKY 59 M+VG G G +G+ + L + G +V + N T +K + S + + Sbjct: 1 MKVGINGFGRIGRQVFRILHERGVEVALINDLTDNKTLAHLLKYDSTYGRFPGAVGYDEE 60 Query: 60 TIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGR--FVE 117 + + D A + + G G + ST K A G + + Sbjct: 61 NLYV--DGKAIRATAIKDPREIPWKQAGVGVVVESTGVFTDGEK-ARAHLEAGAKKVIIT 117 Query: 118 GP 119 P Sbjct: 118 AP 119 >1XDW-A nrPDB Length = 331 Score = 30.4 bits (67), Expect = 0.87, Method: Composition-based stats. Identities = 23/124 (18%), Positives = 46/124 (37%), Gaps = 17/124 (13%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62 VG +GLG +G+ + G V + K E S EV++K Sbjct: 149 VGVVGLGRIGRVAAQIFHGMGATVIGEDVFEIKGIE----DYCTQVSLDEVLEKSDIITI 204 Query: 63 ---MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAIT-----GKGGR 114 + + A ++ F L+++ +G ++ + + + EA+ G G Sbjct: 205 HAPYIKENGAVVTRDF-----LKKMKDGAILVNCARGQLVDTEAVIEAVESGKLGGYGCD 259 Query: 115 FVEG 118 ++G Sbjct: 260 VLDG 263 >1PS9-A nrPDB Length = 671 Score = 30.4 bits (67), Expect = 0.96, Method: Composition-based stats. Identities = 18/105 (17%), Positives = 35/105 (33%), Gaps = 9/105 (8%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNR--------TLSKCDELVEHGASVCESPAEVI 54 + +G G G A ++N G +VT+++ ++K E +I Sbjct: 376 LAVVGAGPAGLAFAINAAARGHQVTLFDAHSEIGGQFNIAKQIPGKEEFYETLRYYRRMI 435 Query: 55 KKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAE 99 + T+ + A FD+ + I ID + Sbjct: 436 EVTGVTLKLNHTVTADQLQAFDETILASGIVPRTPPID-GIDHPK 479 >3PGJ-A nrPDB Length = 302 Score = 30.4 bits (67), Expect = 1.0, Method: Composition-based stats. Identities = 28/123 (22%), Positives = 48/123 (39%), Gaps = 16/123 (13%) Query: 3 VGFLGLGIMGKAMSMNLLKNG-FKVTVWNRTLSKCDEL----VEHGASVCESPAEVIKKC 57 + +G G + + LL +TV NRT +K ++L +G ++ ++ + Sbjct: 150 ILLIGAGGAARGVLKPLLDQQPASITVTNRTFAKAEQLAELVAAYGEVKAQAFEQLKQSY 209 Query: 58 KYTIAMLSDP-----CAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKI--NEAITG 110 I S A V+F V + GKGY TV + + + +AI G Sbjct: 210 DVIINSTSASLDGELPAIDPVIFSSRSVCYDMMYGKGY----TVFNQWARQHGCAQAIDG 265 Query: 111 KGG 113 G Sbjct: 266 LGM 268 >3DDL-A nrPDB Length = 273 Score = 30.1 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 11/46 (23%), Positives = 19/46 (41%), Gaps = 3/46 (6%) Query: 12 GKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKC 57 G ++ L K G+ V ++N +K +E G +V E Sbjct: 231 GYTIADVLAKAGYGVLIYNIAKAKSEE---EGFNVSEMVEPATASA 273 >5NMX-A nrPDB Length = 425 Score = 30.1 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 11/30 (36%), Positives = 15/30 (50%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNR 31 V LG G G + L + GF+V V+ R Sbjct: 3 RVAVLGAGPSGLTAARYLKQAGFEVMVFER 32 >5X6R-A nrPDB Length = 420 Score = 30.1 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 8/28 (28%), Positives = 17/28 (60%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWN 30 V +G G++G ++ K G+ VT+++ Sbjct: 31 VAIIGAGLVGCLAALAFSKEGYNVTLYD 58 >1DOH-A nrPDB Length = 283 Score = 30.1 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 25/157 (15%), Positives = 49/157 (31%), Gaps = 19/157 (12%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTV-WNRTLSKCDELVEH---GASVCESPAEVIKKCK 58 V G GI G+ M+M L + G KV V + + +E+V S + + Sbjct: 34 VTGAGRGI-GREMAMELGRRGCKVIVNYANSTESAEEVVAAIKKNGSDAACVKANVGVVE 92 Query: 59 YTIAMLSDPCAALS-----------VVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEA 107 + M + V F + + + + + + + Sbjct: 93 DIVRMFEEAVKIFGKLDIVCSNSGVVSFGHVKDVTPEEFDRVFTINTRGQFFVAREAYKH 152 Query: 108 ITGKGGRFVEGPVSGSKKPAEDGQLIILAAGDKALFE 144 + G + G ++G K + +G K E Sbjct: 153 LEIGGRLILMGSITGQAKAV---PKHAVYSGSKGAIE 186 >2WTB-A nrPDB Length = 725 Score = 30.1 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 9/46 (19%), Positives = 21/46 (45%), Gaps = 4/46 (8%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVC 47 +V +G G+MG ++ L+ + + V + ++ +E G Sbjct: 314 KVAIIGGGLMGSGIATALILSNYPVIL----KEVNEKFLEAGIGRV 355 >3W8X-A nrPDB Length = 468 Score = 29.7 bits (65), Expect = 1.4, Method: Composition-based stats. Identities = 13/91 (14%), Positives = 33/91 (36%), Gaps = 7/91 (7%) Query: 28 VWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIAMLSDPCAALSVVFDKGGVLEQICEG 87 +WN T+ + L+ S + + + +++ S+ +C+G Sbjct: 40 IWNGTIDRRPALIARCTST-PDVVAAVSFARKSGLLVAVRGGGHSMAG------HSVCDG 92 Query: 88 KGYIDMSTVDAETSLKINEAITGKGGRFVEG 118 ID+S +++ + +GG + Sbjct: 93 GIVIDLSLMNSIKVSRRLRRARAQGGCLLGA 123 >2E18-A nrPDB Length = 257 Score = 29.7 bits (65), Expect = 1.4, Method: Composition-based stats. Identities = 35/191 (18%), Positives = 57/191 (29%), Gaps = 28/191 (14%) Query: 103 KINEAITGKGGRFVEGPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQ 162 +I E I KG V +SG A L A G + + +P F+ L Sbjct: 12 RILEFIREKGNNGVVIGISGGVDSATVAYLATKALGKEKVLGLIMPYFENKDVEDAKLVA 71 Query: 163 VGNGAKMKLIVNMIMGSMMNAFSEGLVL-ADKSGLS--------------SDTLLDILDL 207 G K+I + ++++F E L L D+ GL +++L I+ Sbjct: 72 EKLGIGYKVIN---IKPIVDSFVENLELNLDRKGLGNIMSRTRMIMLYAHANSLGRIVLG 128 Query: 208 GAMTNPMFKGKGPSMNKS--SYPPAFPLKHQQKDMRLALALGDENAVSMPVAAAANEAFK 265 + + G Y P L + + V + Sbjct: 129 TSNRSEFLTGYFTKWGDGASDYAPIINLYKTE-----VWEIAKRIGVP---ERIVKKKPS 180 Query: 266 KARSLGLGDLD 276 G D D Sbjct: 181 AGLWEGQTDED 191 >1BW9-B nrPDB Length = 356 Score = 29.7 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 14/104 (13%), Positives = 29/104 (27%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60 + V GLG +G +++ + G ++ V + + V G + + C Sbjct: 177 LTVLVQGLGAVGGSLASLAAEAGAQLLVADTDTERVAHAVALGHTAVALEDVLSTPCDVF 236 Query: 61 IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKI 104 V + D + D + I Sbjct: 237 APCAMGGVITTEVARTLDCSVVAGAANNVIADEAASDILHARGI 280 >6APH-A nrPDB Length = 445 Score = 29.7 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 17/116 (14%), Positives = 32/116 (27%), Gaps = 9/116 (7%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTI 61 V G G +GK + + G VTV + G + V+ I Sbjct: 228 RVVVCGFGDVGKGTAASFRGAGSIVTVTEIDPICALQAAMEGYE-VKQLDTVVDNADIII 286 Query: 62 AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVE 117 + G E++ + ++ + + + G VE Sbjct: 287 TTTGNFGIVR------GEHFEKMKDKTIVCNIG--HFDNEIDMAWLNKNHGATKVE 334 >3NT2-A nrPDB Length = 344 Score = 29.7 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 18/45 (40%), Gaps = 3/45 (6%) Query: 1 MEVGFLGLGIMGK---AMSMNLLKNGFKVTVWNRTLSKCDELVEH 42 + +G +G G +GK N L V V + ++VE Sbjct: 3 LRIGVIGTGAIGKEHINRITNKLSGAEIVAVTDVNQEAAQKVVEQ 47 >3WFI-A nrPDB Length = 312 Score = 29.7 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 26/61 (42%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60 M++ G G MG + L ++G +V + + ++ EHG + EV K Sbjct: 1 MKIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGLQANFNGKEVEAKLPIV 60 Query: 61 I 61 + Sbjct: 61 L 61 >1ZFN-A nrPDB Length = 253 Score = 29.7 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 8/27 (29%), Positives = 13/27 (48%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTV 28 +V +GLG +G ++ L G V Sbjct: 32 QVLIIGLGGLGTPAALYLAGAGVGTLV 58 >2EKL-A nrPDB Length = 313 Score = 29.7 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 14/94 (14%), Positives = 34/94 (36%), Gaps = 8/94 (8%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRT--LSKCDELVEHGASVCESPAEVIKKCKYT 60 +G +G G +G + + G KV ++ K +++ S E++K Sbjct: 145 IGIVGFGRIGTKVGIIANAMGMKVLAYDILDIREKAEKINAK----AVSLEELLKNSDVI 200 Query: 61 IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMS 94 ++ A ++ E + + ++ S Sbjct: 201 SLHVTVSKDAKPIIDYPQ--FELMKDNVIIVNTS 232 >6ABI-A nrPDB Length = 358 Score = 29.7 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 14/110 (12%), Positives = 36/110 (32%), Gaps = 4/110 (3%) Query: 4 GFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIAM 63 G +G G +G+ + L KV ++ + ++ + S E+ Sbjct: 173 GIIGTGKIGQILIKILRGFDMKVIAYDLFPN--QKVADELGFEYVSLDELYANSDIISLN 230 Query: 64 LSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGG 113 ++ + + ++ +G ++ S + EA+ K Sbjct: 231 CPLTKDTKYMINRRSML--KMKDGVILVNTGRGMLIDSADLVEALKDKKI 278 >3UP5-A nrPDB Length = 545 Score = 29.3 bits (64), Expect = 1.8, Method: Composition-based stats. Identities = 10/38 (26%), Positives = 17/38 (44%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDEL 39 VG +G G G + + ++ V+ RT + C L Sbjct: 187 RVGVIGTGATGVQIIPIAAETAKELYVFQRTPNWCTPL 224 >3KTD-A nrPDB Length = 341 Score = 29.3 bits (64), Expect = 1.9, Method: Composition-based stats. Identities = 18/116 (15%), Positives = 35/116 (30%), Gaps = 2/116 (1%) Query: 17 MNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVI--KKCKYTIAMLSDPCAALSVV 74 +L V +NR+ S V+ G V + + + +L+ P A+ + Sbjct: 25 RDLHAANHSVFGYNRSRSGAKSAVDEGFDVSADLEATLQRAAAEDALIVLAVPMTAIDSL 84 Query: 75 FDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSGSKKPAEDG 130 D + + T + N G + G + + DG Sbjct: 85 LDAVHTHAPNNGFTDVVSVKTAVYDAVKARNMQHRYVGSHPMAGTANSGWSASMDG 140 >4PZE-A nrPDB Length = 284 Score = 29.3 bits (64), Expect = 1.9, Method: Composition-based stats. Identities = 22/108 (20%), Positives = 45/108 (41%), Gaps = 7/108 (6%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62 VG +G G MG ++ G V + + + D V+ G + S + + K + Sbjct: 6 VGIVGAGTMGNGIAQACAVVGLNVVMVDIS----DAAVQKGVATVASSLDRLIKKEKLTE 61 Query: 63 MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITG 110 +D +AL+ + + + I+ +T + + +KI + I G Sbjct: 62 --ADKASALARIKG-STSYDDLKATDIVIEAATENYDLKVKILKQIDG 106 >2TMD-A nrPDB Length = 729 Score = 29.3 bits (64), Expect = 1.9, Method: Composition-based stats. Identities = 10/44 (22%), Positives = 21/44 (47%), Gaps = 1/44 (2%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASV 46 V +G G G + L+++G+ V + + T K + A++ Sbjct: 392 VLIVGAGPSGSEAARVLMESGYTVHLTD-TAEKIGGHLNQVAAL 434 >5BSH-A nrPDB Length = 277 Score = 29.3 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 41/249 (16%), Positives = 82/249 (32%), Gaps = 41/249 (16%) Query: 3 VGFLGLGIMGKAMSMNLLKNGF------KVTVWNRTLSKCDELVEHGASVCESPAEVIKK 56 +GF+G G M ++++ +++G K + + ++ G +V S +V++ Sbjct: 16 LGFIGAGKMAESIAKGAVRSGVLSPSRIKTAIHS-NPARRTAFESIGITVLSSNDDVVRD 74 Query: 57 CKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKG-GRF 115 + + P VV +L + D V +K+ + G RF Sbjct: 75 SNVVVFSVK-PQLLKDVVLKLKPLLTK--------DKLLVSVAAGIKMKDLQEWAGHERF 125 Query: 116 VE-GPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLGK----RSFYL----GQVGNG 166 + P + + + + A + F +GK Y G G+G Sbjct: 126 IRVMPNTAATVGEAASVMSLGGAATEEDANLISQLFGSIGKIWKADDKYFDAITGLSGSG 185 Query: 167 AKMKLIVNMIMGSMMNAFSEGLVLADKSGLSSDTLLD-----ILDLGAMTNPMFKGKGPS 221 + + A ++G +GL D L +L +M K G Sbjct: 186 PAY-------IYLAIEALADG---GVAAGLPRDLALSLASQTVLGAASMATQSGKHPGQL 235 Query: 222 MNKSSYPPA 230 + + P Sbjct: 236 KDDVTSPGG 244 >2BW0-A nrPDB Length = 329 Score = 29.3 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 19/86 (22%), Positives = 33/86 (38%), Gaps = 6/86 (6%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKV----TVWNRTLSKCDELVEHGASVCESPAEVIKK 56 M++ +G + G+ + +L K G +V TV ++ K D L A P + Sbjct: 23 MKIAVIGQSLFGQEVYCHLRKEGHEVVGVFTVPDKD-GKADPLGLE-AEKDGVPVFKYSR 80 Query: 57 CKYTIAMLSDPCAALSVVFDKGGVLE 82 + L D A + + VL Sbjct: 81 WRAKGQALPDVVAKYQALGAELNVLP 106 >3J9R-A nrPDB Length = 386 Score = 29.3 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 19/140 (13%), Positives = 37/140 (26%), Gaps = 32/140 (22%) Query: 27 TVWNRTLSKCDELVEHGASVCESPAEVIKK-------------------------CKYTI 61 ++NR +V G E+P + + Sbjct: 71 AIYNR---AQAVIVAVGVETAETPEAQASAVIGGISAAGERTGLQALLDGKSRFNAQPRL 127 Query: 62 AMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVS 121 + A +V G+ E++ +D E ++ + K V+ V Sbjct: 128 LVAPGHSAQQAVATAMDGLAEKLRA-IAILDGPNSTDEAAVAYAKNFGSKRLFMVDPGVQ 186 Query: 122 ---GSKKPAEDGQLIILAAG 138 + A + AAG Sbjct: 187 VWDSATNAARNAPASAYAAG 206 >3K6J-A nrPDB Length = 460 Score = 29.3 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 11/36 (30%), Positives = 18/36 (50%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDE 38 V +G G MGKAM++ G + + R +C + Sbjct: 57 VAIIGGGTMGKAMAICFGLAGIETFLVVRNEQRCKQ 92 >1HYH-A nrPDB Length = 309 Score = 29.3 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 29/78 (37%), Gaps = 14/78 (17%) Query: 2 EVGFLGLGIMGKAMSMNLLKNG----FKVTVWNRTLSKCDE---------LVEHGASVCE 48 ++G +GLG +G A++ L+ G + N K D+ L HG V Sbjct: 3 KIGIIGLGNVGAAVAHGLIAQGVADDYVFIDANEAKVKADQIDFQDAMANLEAHGNIVIN 62 Query: 49 SPAEVIKKCKYTIAMLSD 66 + I+ L + Sbjct: 63 D-WAALADADVVISTLGN 79 >2CBN-A nrPDB Length = 306 Score = 29.3 bits (64), Expect = 2.1, Method: Composition-based stats. Identities = 19/124 (15%), Positives = 39/124 (31%), Gaps = 20/124 (16%) Query: 66 DPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSG--- 122 + A + G + +++ GK T+ E +IN G ++ PV G Sbjct: 161 NAQALKAAGVPPGPLFQELKAGK------TITLEDGRQIN------GADYLAAPVPGKAL 208 Query: 123 ---SKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGS 179 D L + D + E ++ + ++ G L +G Sbjct: 209 AIFGDTGPCDAALDLAKGVDVMVHEATLDI--TMEAKANSRGHSSTRQAATLAREAGVGK 266 Query: 180 MMNA 183 ++ Sbjct: 267 LIIT 270 >4OVI-A nrPDB Length = 542 Score = 29.3 bits (64), Expect = 2.2, Method: Composition-based stats. Identities = 13/56 (23%), Positives = 21/56 (37%), Gaps = 2/56 (3%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKK 56 VG +G G G +S + K ++ V+ RT A + +KK Sbjct: 187 QRVGVIGTGSSGIQVSPQIAKQAAELFVFQRTPHFAVP--ARNAPLDPEFLADLKK 240 >3L9X-A nrPDB Length = 413 Score = 29.3 bits (64), Expect = 2.2, Method: Composition-based stats. Identities = 18/92 (19%), Positives = 30/92 (32%), Gaps = 8/92 (8%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHG-------ASVCESPAEV 53 M V G G G+ LL +G K+ V + + L + G A+ + Sbjct: 5 MRVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDATRMDLLESA 64 Query: 54 -IKKCKYTIAMLSDPCAALSVVFDKGGVLEQI 84 K + I + DP L + + Sbjct: 65 GAAKAEVLINAIDDPQTNLQLTEMVKEHFPHL 96 >4YRY-B nrPDB Length = 468 Score = 28.9 bits (63), Expect = 2.6, Method: Composition-based stats. Identities = 10/59 (16%), Positives = 21/59 (35%), Gaps = 7/59 (11%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60 +V +G G G + +L K G+ V ++ + + G + E + Sbjct: 142 KVAVVGSGPAGLTAAADLAKMGYHVDIF-------EAFHKPGGVLVYGIPEFRLPKRIV 193 >1E5Q-A nrPDB Length = 450 Score = 28.9 bits (63), Expect = 2.7, Method: Composition-based stats. Identities = 24/123 (19%), Positives = 42/123 (34%), Gaps = 21/123 (17%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEV--------- 53 V LG G + + L +G KVTV RTL +L +P + Sbjct: 6 VLMLGSGFVTRPTLDVLTDSGIKVTVACRTLESAKKLSA--GVQHSTPISLDVNDDAALD 63 Query: 54 --IKKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGK 111 + K I+++ F + I + K + S V +++++A Sbjct: 64 AEVAKHDLVISLIPYT-------FHATVIKSAIRQKKHVVTTSYVSPAM-MELDQAAKDA 115 Query: 112 GGR 114 G Sbjct: 116 GIT 118 >5U9P-A nrPDB Length = 265 Score = 28.5 bits (62), Expect = 3.2, Method: Composition-based stats. Identities = 6/65 (9%), Positives = 23/65 (35%), Gaps = 7/65 (10%) Query: 12 GKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIAMLSDPCAAL 71 G ++ L + G + + +R K A++ + + + +++ Sbjct: 33 GLTLARGLAEAGAAIVINDRNEEKA-------ATLARRFRDEGFAADHAVFDVAEHAQVR 85 Query: 72 SVVFD 76 + + + Sbjct: 86 AAIDE 90 >3OSU-A nrPDB Length = 246 Score = 28.5 bits (62), Expect = 3.4, Method: Composition-based stats. Identities = 13/59 (22%), Positives = 28/59 (47%), Gaps = 4/59 (6%) Query: 12 GKAMSMNLLKNGFKVTV-WNRTLSKCDELVEH-GASVCESPA--EVIKKCKYTIAMLSD 66 G+++++ L + G+ V V + + K + +VE A +S A + AM+ + Sbjct: 17 GRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVADADEVKAMIKE 75 >2DBZ-A nrPDB Length = 334 Score = 28.5 bits (62), Expect = 3.5, Method: Composition-based stats. Identities = 7/98 (7%), Positives = 40/98 (40%), Gaps = 4/98 (4%) Query: 13 KAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIAMLSDPCAALS 72 +A++ ++ ++RT +E+ + + +++++ + + + Sbjct: 163 QAIAKRAKGFNMRILYYSRTRK--EEVERELNAEFKPLEDLLRESDFVVLAVPLTRETYH 220 Query: 73 VVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITG 110 ++ ++ L+ + + I+++ + + +A+ Sbjct: 221 LINEER--LKLMKKTAILINIARGKVVDTNALVKALKE 256 >4J0E-A nrPDB Length = 320 Score = 28.5 bits (62), Expect = 3.6, Method: Composition-based stats. Identities = 9/40 (22%), Positives = 17/40 (42%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEH 42 V +G G MG ++ +GF V + + D ++ Sbjct: 17 VAIVGSGQMGSGIAQVTASSGFNVMLADVNKKALDRAMKA 56 >2PAJ-A nrPDB Length = 492 Score = 28.5 bits (62), Expect = 3.6, Method: Composition-based stats. Identities = 22/156 (14%), Positives = 45/156 (28%), Gaps = 6/156 (3%) Query: 67 PCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSGSKKP 126 + V D+ +L Q G + S + + + G PVS Sbjct: 283 YAHLVKVDADEIALLAQTGTGVAHCPQSNGRLGSGICPVREMADAGV-----PVSIGVDG 337 Query: 127 AEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMMNAFSE 186 A + + + + +L + ++ G GA I +I + Sbjct: 338 AASNEAADMISEVHMTWLAQRARLGMLAQPAYRGGSFEGGAGAASIAEVIHWGT-AGGAR 396 Query: 187 GLVLADKSGLSSDTLLDILDLGAMTNPMFKGKGPSM 222 + L + ++ DI F P++ Sbjct: 397 VMGLDEVGKVAVGYAADIAVYRLDDPRYFGLHDPAI 432 >2PB9-A nrPDB Length = 195 Score = 28.5 bits (62), Expect = 3.8, Method: Composition-based stats. Identities = 13/49 (26%), Positives = 24/49 (48%), Gaps = 3/49 (6%) Query: 21 KNGFKVTVWNRTLSKCDELVEHGASV---CESPAEVIKKCKYTIAMLSD 66 + GFKV+ ++R + + GA++ E+ + IK+ I L D Sbjct: 114 ERGFKVSFYDRREEPEEIKAKEGATIPWGIETAIKRIKERPDIIYHLGD 162 >6BMQ-A nrPDB Length = 523 Score = 28.1 bits (61), Expect = 3.9, Method: Composition-based stats. Identities = 10/33 (30%), Positives = 15/33 (45%) Query: 21 KNGFKVTVWNRTLSKCDELVEHGASVCESPAEV 53 + G KV + NRT + EL E S ++ Sbjct: 385 EKGAKVVIANRTYERALELAEAIGGKALSLTDL 417 >3ZV3-A nrPDB Length = 281 Score = 28.1 bits (61), Expect = 4.0, Method: Composition-based stats. Identities = 19/90 (21%), Positives = 34/90 (37%), Gaps = 9/90 (10%) Query: 7 GLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDEL-VEHGASVCESPAEVIKKCKYTIAMLS 65 G +G+A+ + G +V V +++ + EL V HG + + + L Sbjct: 13 GASGLGRALVDRFVAEGARVAVLDKSAERLRELEVAHGGNAVGVVGD--------VRSLQ 64 Query: 66 DPCAALSVVFDKGGVLEQICEGKGYIDMST 95 D A G ++ + G D ST Sbjct: 65 DQKRAAERCLAAFGKIDTLIPNAGIWDYST 94 >5EVJ-A nrPDB Length = 387 Score = 28.1 bits (61), Expect = 4.2, Method: Composition-based stats. Identities = 12/66 (18%), Positives = 21/66 (31%), Gaps = 2/66 (3%) Query: 49 SPAEVIKKCKYTI-AMLSD-PCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINE 106 S K + A L+D P + G + EG +D+ + + Sbjct: 44 SACTAAKAPPPAVRAALADVPTEVKEKFWGCGNPIPAGIEGLRVLDLGAGSGRDAYVAAK 103 Query: 107 AITGKG 112 + KG Sbjct: 104 LVGEKG 109 >6IHE-A nrPDB Length = 303 Score = 28.1 bits (61), Expect = 4.4, Method: Composition-based stats. Identities = 18/106 (16%), Positives = 41/106 (38%), Gaps = 5/106 (4%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGF--KVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKY 59 +VGF+G G +G+ ++ + L +G + +++ D+ + + IK Sbjct: 2 KVGFIGAGKIGQTIAYSALVSGAVDEAVIYDIIPELPDKFEHELRHAFAT--KGIKANVL 59 Query: 60 TIAMLSDPCAALSVVFDKGGV-LEQICEGKGYIDMSTVDAETSLKI 104 L D VV G + ++D + + + + K+ Sbjct: 60 GTNSLDDVSGMDIVVISAGKPRKPGMSRRDLFVDNAKIMIDLAQKL 105 >6J0Z-C nrPDB Length = 491 Score = 28.1 bits (61), Expect = 4.8, Method: Composition-based stats. Identities = 12/54 (22%), Positives = 20/54 (37%), Gaps = 1/54 (1%) Query: 2 EVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIK 55 +V +G G G ++ L G V V ++ E G S + E + Sbjct: 7 DVVVVGAGPTGLMLAGELRLAGVSVVVLDKLAEPIKESRALGFS-ARTIEEFAQ 59 >1UB3-A nrPDB Length = 220 Score = 28.1 bits (61), Expect = 5.0, Method: Composition-based stats. Identities = 8/49 (16%), Positives = 17/49 (34%) Query: 88 KGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSGSKKPAEDGQLIILA 136 K ++ E ++ EA G F++ + A + +L Sbjct: 122 KVILETGYFSPEEIARLAEAAIRGGADFLKTSTGFGPRGASLEDVALLV 170 >2DZB-A nrPDB Length = 294 Score = 27.7 bits (60), Expect = 5.3, Method: Composition-based stats. Identities = 19/184 (10%), Positives = 52/184 (28%), Gaps = 13/184 (7%) Query: 95 TVDAETSLKINEAITGKGGRFVEGPVSGSKKPAEDGQLIILAAGDKALFEESIPAFDVLG 154 +D E +L+ + +G ++ ++ A + + +P + + Sbjct: 48 YLDPERALERAREMVAEGADILDLGAESTRPGAAPVPV-------EEEKRRLLPVLEAVL 100 Query: 155 K-----RSFYLGQVGNGAKMKLIVNMIMGSMMNAFSEGLVLADKSGLSSDTL-LDILDLG 208 +KL +++ + LA + G+++ + + + D Sbjct: 101 SLGVPVSVDTRKPEVAEEALKLGAHLLNDVTGLRDERMVALAARHGVAAVVMHMPVPDPA 160 Query: 209 AMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDMRLALALGDENAVSMPVAAAANEAFKKAR 268 M + K+ ++ L G + A + Sbjct: 161 TMMAHARYRDVVAEVKAFLEAQARRALSAGVPQVVLDPGFGFGKLLEHNLALLRRLDEIV 220 Query: 269 SLGL 272 +LG Sbjct: 221 ALGH 224 >3WYE-A nrPDB Length = 256 Score = 27.7 bits (60), Expect = 5.5, Method: Composition-based stats. Identities = 19/97 (19%), Positives = 34/97 (35%), Gaps = 15/97 (15%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTV--WNRTLSKCDELVEHGASVCESPAEVIKKCKYT 60 V G GI GKA+++ L+K+GF V + +N +K V + Sbjct: 7 VTGAGQGI-GKAIALRLVKDGFAVAIADYNDATAKA---------VASEINQAGGHAVAV 56 Query: 61 IAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVD 97 +SD + V L ++ + + Sbjct: 57 KVDVSDRDQVFAAVEQARKTLGGF---DVIVNNAGIA 90 >1PJB-A nrPDB Length = 361 Score = 27.7 bits (60), Expect = 5.6, Method: Composition-based stats. Identities = 13/85 (15%), Positives = 30/85 (35%), Gaps = 11/85 (12%) Query: 15 MSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCE-------SPAEVIKKCKYTIAMLSDP 67 M++ L G +V +++ + + L S E + + I + P Sbjct: 185 MAVGL---GAQVQIFDINVERLSYLETLFGSRVELLYSNSAEIETAVAEADLLIGAVLVP 241 Query: 68 CAALSVVFDKGGVLEQICEGKGYID 92 + + ++EQ+ G +D Sbjct: 242 GR-RAPILVPASLVEQMRTGSVIVD 265 >5IOB-A nrPDB Length = 348 Score = 27.7 bits (60), Expect = 5.9, Method: Composition-based stats. Identities = 17/159 (10%), Positives = 37/159 (23%), Gaps = 21/159 (13%) Query: 95 TVDAETSLKINE----AITGKGGRFVEGPV---------------SGSKKPAEDGQLIIL 135 T+ E + E + G PV + Sbjct: 116 TMTPEQVEDLAEILGTGLAAHGVTVNFAPVVDVDAWGLPVVGDRSFSNDPAVAATYATAF 175 Query: 136 AAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMMNAFSEGLVLADKSG 195 A G + P F G + ++ + + + + L D + Sbjct: 176 AKGLSKVG--ITPVFKHFPGHGRASGDSHTQDVVTPALDELKTYDLIPYGQALSETDGAV 233 Query: 196 LSSDTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLK 234 + ++ L + + + + YP P Sbjct: 234 MVGHMIVPGLGTDGVPSSIDPATYQLLRSGDYPGGVPFD 272 >3HWR-A nrPDB Length = 318 Score = 27.7 bits (60), Expect = 5.9, Method: Composition-based stats. Identities = 12/97 (12%), Positives = 28/97 (28%), Gaps = 13/97 (13%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASV------------CE 48 M+V +G G +G L + G +V + R + G + Sbjct: 20 MKVAIMGAGAVGCYYGGMLARAGHEVILIAR-PQHVQAIEATGLRLETQSFDEQVKVSAS 78 Query: 49 SPAEVIKKCKYTIAMLSDPCAALSVVFDKGGVLEQIC 85 S ++ + + + + K + + Sbjct: 79 SDPSAVQGADLVLFCVKSTDTQSAALAMKPALAKSAL 115 >2DC1-A nrPDB Length = 236 Score = 27.7 bits (60), Expect = 6.3, Method: Composition-based stats. Identities = 11/27 (40%), Positives = 18/27 (66%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVT 27 M VG +G G +GK ++ L +NGF++ Sbjct: 1 MLVGLIGYGAIGKFLAEWLERNGFEIA 27 >4OMU-A nrPDB Length = 283 Score = 27.7 bits (60), Expect = 6.7, Method: Composition-based stats. Identities = 18/100 (18%), Positives = 30/100 (30%), Gaps = 11/100 (11%) Query: 19 LLKNGFKVTVWNRTLSKCDELVEH----GASVCESPAEVIKKCKYTIAMLSDPCAALSVV 74 L + + NRT+ K ++L G V A + + I S A + Sbjct: 139 LAHKPQSLVIANRTVEKAEQLAREFDELGPVVASGFAWLQEPVDVIINATSASLAGE--L 196 Query: 75 FDKGGVLEQICEGKGYI-DMSTVDAETSLKINEAITGKGG 113 L + G+ DM + + T G Sbjct: 197 PPIADSL--VEAGRTVCYDMMYG--KEPTPFCQWATKLGA 232 >5XGV-A nrPDB Length = 462 Score = 27.4 bits (59), Expect = 6.9, Method: Composition-based stats. Identities = 17/112 (15%), Positives = 35/112 (31%), Gaps = 2/112 (1%) Query: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62 V G G +G ++ L G V R + + G ++ + E+ + + Sbjct: 4 VIIAGGGPVGLMLACELGLAGVDTVVLERHDAPREP--SRGGAINATVVELFTQRGIMES 61 Query: 63 MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGR 114 + D F + + G + A+ ++ E G R Sbjct: 62 LRDDGFEFRMAHFAHIPLAPERVPGDRAFSFAVPHAQVERRLEERARSLGVR 113 >1LSS-A nrPDB Length = 140 Score = 27.4 bits (59), Expect = 7.0, Method: Composition-based stats. Identities = 7/42 (16%), Positives = 18/42 (42%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEH 42 M + G+G +G ++ +L + G + + + C + Sbjct: 5 MYIIIAGIGRVGYTLAKSLSEKGHDIVLIDIDKDICKKASAE 46 >5UAU-A nrPDB Length = 322 Score = 27.4 bits (59), Expect = 7.4, Method: Composition-based stats. Identities = 13/71 (18%), Positives = 25/71 (35%), Gaps = 6/71 (8%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNG----FKVTVW--NRTLSKCDELVEHGASVCESPAEVI 54 M VGF+G G + A++ G K+ + L+ L + G + E + Sbjct: 23 MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETV 82 Query: 55 KKCKYTIAMLS 65 + + Sbjct: 83 QHSDVLFLAVK 93 >2V3B-A nrPDB Length = 384 Score = 27.4 bits (59), Expect = 7.4, Method: Composition-based stats. Identities = 13/43 (30%), Positives = 19/43 (44%) Query: 97 DAETSLKINEAITGKGGRFVEGPVSGSKKPAEDGQLIILAAGD 139 + + + G G RF GPV S K A +G L+ G+ Sbjct: 186 HPAAAKAVQAGLEGLGVRFHLGPVLASLKKAGEGLEAHLSDGE 228 >5CJE-A nrPDB Length = 393 Score = 27.4 bits (59), Expect = 8.3, Method: Composition-based stats. Identities = 14/68 (20%), Positives = 27/68 (39%), Gaps = 11/68 (16%) Query: 13 KAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIAMLSDPCAALS 72 +AM+ LL G + TV L+ +G + + + + + +L A Sbjct: 224 RAMAFILLVAGHETTV---------NLITNGVHTLLTHPDQLAALRADMTLLD--GAVEE 272 Query: 73 VVFDKGGV 80 V+ +G V Sbjct: 273 VLRFEGPV 280 >2VDC-G nrPDB Length = 456 Score = 27.4 bits (59), Expect = 8.6, Method: Composition-based stats. Identities = 26/156 (16%), Positives = 47/156 (30%), Gaps = 28/156 (17%) Query: 19 LLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIAMLSDPCAALSVVFDKG 78 L G++V V++R + L+ +G + V++ + +L+D F+ G Sbjct: 141 LRAKGYEVHVYDR-YDRMGGLLVYGIPGFKLEKSVVE---RRVKLLADAGVIYHPNFEVG 196 Query: 79 GVLEQICEGKGYIDMSTVDAETSLKINEAITGKG---GRFVEGPVSG-SKKPAEDGQLI- 133 E K + G R ++ P SG A L Sbjct: 197 RDASL--------------PELRRKHVAVLVATGVYKARDIKAPGSGLGNIVAALDYLTT 242 Query: 134 ---ILAAGDKALFEESIPAFDVLGKRSFYLGQVGNG 166 + +E + + GK LG Sbjct: 243 SNKVSLGDTVEAYENG--SLNAAGKHVVVLGGGDTA 276 >2GRA-A nrPDB Length = 277 Score = 27.4 bits (59), Expect = 8.6, Method: Composition-based stats. Identities = 13/71 (18%), Positives = 25/71 (35%), Gaps = 6/71 (8%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNG----FKVTVW--NRTLSKCDELVEHGASVCESPAEVI 54 M VGF+G G + A++ G K+ + L+ L + G + E + Sbjct: 3 MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETV 62 Query: 55 KKCKYTIAMLS 65 + + Sbjct: 63 QHSDVLFLAVK 73 >4HB9-A nrPDB Length = 412 Score = 27.0 bits (58), Expect = 9.0, Method: Composition-based stats. Identities = 10/43 (23%), Positives = 22/43 (51%) Query: 15 MSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKC 57 ++ L K+G KVT++ R + L +G + + +++C Sbjct: 16 LAHGLRKHGIKVTIYERNSAASSILPGYGIHINSFGKQALQEC 58 >4Y4N-A nrPDB Length = 286 Score = 27.0 bits (58), Expect = 9.3, Method: Composition-based stats. Identities = 10/31 (32%), Positives = 16/31 (51%) Query: 1 MEVGFLGLGIMGKAMSMNLLKNGFKVTVWNR 31 ++V +G G G + + K G+KV V R Sbjct: 53 VDVAIVGGGPSGLTAARYIAKEGYKVVVLER 83 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.305 0.131 0.313 Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,131,066 Number of Sequences: 36641 Number of extensions: 331912 Number of successful extensions: 1744 Number of sequences better than 10.0: 255 Number of HSP's better than 10.0 without gapping: 198 Number of HSP's successfully gapped in prelim test: 122 Number of HSP's that attempted gapping in prelim test: 1421 Number of HSP's gapped (non-prelim): 336 length of query: 289 length of database: 10,336,785 effective HSP length: 96 effective length of query: 193 effective length of database: 6,819,249 effective search space: 1316115057 effective search space used: 1316115057 T: 11 A: 40 X1: 16 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.0 bits) S2: 59 (27.3 bits)