BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9LDC0 (365 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2IF4-A nrPDB 699 0.0 2F4E-A nrPDB 373 e-104 1QZ2-A nrPDB 104 5e-23 5MGX-E nrPDB 96 2e-20 1KT1-A nrPDB 89 4e-18 5OMP-A nrPDB 88 7e-18 1IHG-A nrPDB 74 1e-13 1ROT-A nrPDB 57 2e-08 4TW8-A nrPDB 57 2e-08 1Q1C-A nrPDB 56 3e-08 4DRJ-A nrPDB 55 6e-08 3B7X-A nrPDB 54 8e-08 5L1D-B nrPDB 54 9e-08 2LGO-A nrPDB 53 2e-07 2ND5-A nrPDB 53 2e-07 5T9S-F nrPDB 53 2e-07 3O5D-A nrPDB 52 4e-07 4R0X-A nrPDB 52 5e-07 3O5E-A nrPDB 52 5e-07 6B4P-A nrPDB 50 1e-06 3JXV-A nrPDB 49 3e-06 1R9H-A nrPDB 48 7e-06 4GIV-A nrPDB 47 1e-05 3IHZ-A nrPDB 47 1e-05 5JHE-A nrPDB 47 2e-05 4QT3-A nrPDB 46 2e-05 2Y78-A nrPDB 46 2e-05 6FO1-G nrPDB 46 2e-05 2L2S-A nrPDB 45 3e-05 4I2W-A nrPDB 45 3e-05 5B8I-C nrPDB 44 9e-05 1Q6H-A nrPDB 44 2e-04 1YAT-A nrPDB 43 2e-04 5HWB-A nrPDB 42 4e-04 5I7P-A nrPDB 41 0.001 5HUA-A nrPDB 40 0.002 5I7Q-A nrPDB 39 0.003 5JJT-A nrPDB 39 0.003 1JVW-A nrPDB 38 0.006 2MPH-A nrPDB 37 0.014 2PBC-A nrPDB 36 0.026 5D75-A nrPDB 35 0.038 5AEM-A nrPDB 35 0.038 4NNR-A nrPDB 35 0.038 4JA9-A nrPDB 35 0.058 3UQI-A nrPDB 35 0.066 4JM7-A nrPDB 35 0.076 5CXD-A nrPDB 34 0.083 4JYS-A nrPDB 34 0.11 4MSP-A nrPDB 33 0.13 4I9E-A nrPDB 33 0.19 4DIP-A nrPDB 32 0.31 1Y0O-A nrPDB 32 0.45 1XTP-A nrPDB 31 0.68 4BF8-A nrPDB 31 0.76 6B85-J nrPDB 31 0.84 1A17-A nrPDB 30 1.3 3PR3-A nrPDB 30 2.0 4I1A-A nrPDB 29 2.6 4CGU-A nrPDB 29 3.3 4ODP-A nrPDB 29 3.8 1U61-A nrPDB 28 6.0 6H3J-B nrPDB 28 7.8 >2IF4-A nrPDB Length = 338 Score = 699 bits (1804), Expect = 0.0, Method: Compositional matrix adjust. Identities = 338/338 (100%), Positives = 338/338 (100%) Query: 1 MDESLEHQTQTHDQESEIVTEGSAVVHSEPSQEGNVPPKVDSEAEVLDEKVSKQIIKEGH 60 MDESLEHQTQTHDQESEIVTEGSAVVHSEPSQEGNVPPKVDSEAEVLDEKVSKQIIKEGH Sbjct: 1 MDESLEHQTQTHDQESEIVTEGSAVVHSEPSQEGNVPPKVDSEAEVLDEKVSKQIIKEGH 60 Query: 61 GSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIGVASMKSGE 120 GSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIGVASMKSGE Sbjct: 61 GSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIGVASMKSGE 120 Query: 121 RALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETKEGKARSDMTVEERIGAAD 180 RALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETKEGKARSDMTVEERIGAAD Sbjct: 121 RALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETKEGKARSDMTVEERIGAAD 180 Query: 181 RRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAACL 240 RRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAACL Sbjct: 181 RRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAACL 240 Query: 241 IKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPDDKAI 300 IKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPDDKAI Sbjct: 241 IKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPDDKAI 300 Query: 301 RRELRALAEQEKALYQKQKEMYKGIFKGKDEGGAKSKS 338 RRELRALAEQEKALYQKQKEMYKGIFKGKDEGGAKSKS Sbjct: 301 RRELRALAEQEKALYQKQKEMYKGIFKGKDEGGAKSKS 338 >2F4E-A nrPDB Length = 180 Score = 373 bits (958), Expect = e-104, Method: Compositional matrix adjust. Identities = 180/180 (100%), Positives = 180/180 (100%) Query: 1 MDESLEHQTQTHDQESEIVTEGSAVVHSEPSQEGNVPPKVDSEAEVLDEKVSKQIIKEGH 60 MDESLEHQTQTHDQESEIVTEGSAVVHSEPSQEGNVPPKVDSEAEVLDEKVSKQIIKEGH Sbjct: 1 MDESLEHQTQTHDQESEIVTEGSAVVHSEPSQEGNVPPKVDSEAEVLDEKVSKQIIKEGH 60 Query: 61 GSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIGVASMKSGE 120 GSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIGVASMKSGE Sbjct: 61 GSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIGVASMKSGE 120 Query: 121 RALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETKEGKARSDMTVEERIGAAD 180 RALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETKEGKARSDMTVEERIGAAD Sbjct: 121 RALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETKEGKARSDMTVEERIGAAD 180 >1QZ2-A nrPDB Length = 336 Score = 104 bits (260), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 73/258 (28%), Positives = 139/258 (53%), Gaps = 10/258 (3%) Query: 85 FEDTWHEQQPIELVLGK-EKKELA-GLAIGVASMKSGERALVHVGWELAYGKEGNFSFPN 142 ++D +Q+ + +G+ E +L GL + M+ GE ++V++ A+G G F Sbjct: 55 YKDKLFDQRELRFEIGEGENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKF-Q 113 Query: 143 VPPMADLLYEVEVIGFDETKEGKARSDMTVEERIGAADRRKMDGNSLFKEEKLEEAMQQY 202 +PP A+L YE+ + F++ KE +M EE++ + K G FKE K ++A+ QY Sbjct: 114 IPPNAELKYELHLKSFEKAKES---WEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQY 170 Query: 203 EMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAACLIKLKRYDEAIGHCNIVLTEEEK 262 + ++++ ++ + A A++ HLN+A C +KL+ + AI CN L + Sbjct: 171 KKIVSWL--EYESSFSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSN 228 Query: 263 NPKALFRRGKAKAELGQMDSARDDFRKAQKYAPDDKAIRRELRALAEQEKALYQKQKEMY 322 N K LFRRG+A + + AR DF+K + P++KA + +L ++ + ++K++Y Sbjct: 229 NEKGLFRRGEAHLAVNDFELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLY 288 Query: 323 KGIFK--GKDEGGAKSKS 338 +F+ ++E AK+++ Sbjct: 289 ANMFERLAEEENKAKAEA 306 >5MGX-E nrPDB Length = 290 Score = 96.3 bits (238), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 78/277 (28%), Positives = 122/277 (44%), Gaps = 15/277 (5%) Query: 62 SKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELV--LGKEKKELAGLAIGVASMKSG 119 S+P K +H Q E+ Q+ ELV LG + + L + V M G Sbjct: 25 SRPVKGQVVTVHL-------QTSLENGTRVQEEPELVFTLG-DCDVIQALDLSVPLMDVG 76 Query: 120 ERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETKEGKARSDMTVEERIGAA 179 E A+V + YG +G P +PP A L EV +G +T +ER+ A Sbjct: 77 ETAMVTADSKYCYGPQGRS--PYIPPHAALCLEVT---LKTAVDGPDLEMLTGQERVALA 131 Query: 180 DRRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAAC 239 +R++ GN+ ++ A Y++AI + + + + L +K C N+AA Sbjct: 132 NRKRECGNAHYQRADFVLAANSYDLAIKAITSSAKVDMTFEEEAQLLQLKVKCLNNLAAS 191 Query: 240 LIKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPDDKA 299 +KL Y A+ C++VL + N KALFR+GK A+ G+ A R A K P +K Sbjct: 192 QLKLDHYRAALRSCSLVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKT 251 Query: 300 IRRELRALAEQEKALYQKQKEMYKGIFKGKDEGGAKS 336 I EL L ++ A + +Y+ + AK Sbjct: 252 IHAELSKLVKKHAAQRSTETALYRKMLGNPSRLPAKC 288 >1KT1-A nrPDB Length = 457 Score = 88.6 bits (218), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 60/220 (27%), Positives = 113/220 (51%), Gaps = 6/220 (2%) Query: 108 GLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETKEGKAR 167 G+ + M+ E+ ++H+G +G+ G F + P A+L+YEV + F++ KE Sbjct: 201 GIDKALEKMQREEQCILHLGPRYGFGEAGKPKF-GIEPNAELIYEVTLKSFEKAKES--- 256 Query: 168 SDMTVEERIGAADRRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALA 227 +M +E++ A K G FK K +A+ QY ++++ + + L K + + Sbjct: 257 WEMDTKEKLEQAAIVKEKGTVYFKGGKYVQAVIQYGKIVSWL--EMEYGLSEKESKASES 314 Query: 228 VKNPCHLNIAACLIKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDF 287 LN+A C +KL+ Y +A+ C+ L + N K L+RRG+A+ + + +SA+ DF Sbjct: 315 FLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDF 374 Query: 288 RKAQKYAPDDKAIRRELRALAEQEKALYQKQKEMYKGIFK 327 K + P +KA R ++ ++ K ++ + Y +FK Sbjct: 375 EKVLEVNPQNKAARLQIFMCQKKAKEHNERDRRTYANMFK 414 Score = 53.9 bits (128), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 37/112 (33%), Positives = 55/112 (49%), Gaps = 5/112 (4%) Query: 48 DEKVSKQIIKEGHGSK-PSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKEL 106 D V K + + GHG + P ++HY N + KF+ + +P +GK + + Sbjct: 30 DRGVLKIVKRVGHGEETPMIGDRVYVHYNGKLANGK-KFDSSHDRNEPFVFSIGK-GQVI 87 Query: 107 AGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGF 158 IGVA+MK GE + E AYG G S P +P A L +EVE++ F Sbjct: 88 KAWDIGVATMKKGEICHLLCKPEYAYGATG--SLPKIPSNATLFFEVELLDF 137 >5OMP-A nrPDB Length = 462 Score = 87.8 bits (216), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 59/220 (26%), Positives = 114/220 (51%), Gaps = 6/220 (2%) Query: 108 GLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETKEGKAR 167 G+ + M+ E+ ++++G +G+ G F + P A+L+YEV + F++ KE Sbjct: 206 GIDKALEKMQREEQCILYLGPRYGFGEAGKPKF-GIEPNAELIYEVTLKSFEKAKE---S 261 Query: 168 SDMTVEERIGAADRRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALA 227 +M +E++ A K G FK K +A+ QY ++++ + + L K + + Sbjct: 262 WEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWL--EMEYGLSEKESKASES 319 Query: 228 VKNPCHLNIAACLIKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDF 287 LN+A C +KL+ Y +A+ C+ L + N K L+RRG+A+ + + +SA+ DF Sbjct: 320 FLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDF 379 Query: 288 RKAQKYAPDDKAIRRELRALAEQEKALYQKQKEMYKGIFK 327 K + P +KA R ++ ++ K ++ + +Y +FK Sbjct: 380 EKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFK 419 Score = 52.4 bits (124), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 36/112 (32%), Positives = 56/112 (50%), Gaps = 5/112 (4%) Query: 48 DEKVSKQIIKEGHGSK-PSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKEL 106 D V K + + G+G + P ++HY+ N + KF+ + +P LGK + + Sbjct: 35 DRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGK-KFDSSHDRNEPFVFSLGK-GQVI 92 Query: 107 AGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGF 158 IGVA+MK GE + E AYG G S P +P A L +E+E++ F Sbjct: 93 KAWDIGVATMKKGEICHLLCKPEYAYGSAG--SLPKIPSNATLFFEIELLDF 142 >1IHG-A nrPDB Length = 370 Score = 73.6 bits (179), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 50/144 (34%), Positives = 77/144 (53%), Gaps = 7/144 (4%) Query: 186 GNSLFKEEKLEEAMQQYEMAIAYM-GDDFMFQLY--GKYQDMALAVKNPCHLNIAACLIK 242 GN+ FK + E A+++Y + Y+ G + K Q +AL+ C LNI AC +K Sbjct: 230 GNTFFKSQNWEMAIKKYTKVLRYVEGSRAAAEDADGAKLQPVALS----CVLNIGACKLK 285 Query: 243 LKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPDDKAIRR 302 + + A+ C L + N KAL+RR + L + D A D +KAQ+ AP+DKAI+ Sbjct: 286 MSDWQGAVDSCLEALEIDPSNTKALYRRAQGWQGLKEYDQALADLKKAQEIAPEDKAIQA 345 Query: 303 ELRALAEQEKALYQKQKEMYKGIF 326 EL + ++ KA K+K Y +F Sbjct: 346 ELLKVKQKIKAQKDKEKAAYAKMF 369 >1ROT-A nrPDB Length = 149 Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 40/112 (35%), Positives = 56/112 (50%), Gaps = 5/112 (4%) Query: 48 DEKVSKQIIKEGHGSK-PSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKEL 106 DE V K I +EG G++ P F+HY W + KF+ + + LGK + + Sbjct: 29 DEGVLKVIKREGTGTETPMIGDRVFVHYTGWLLDGT-KFDSSLDRKDKFSFDLGK-GEVI 86 Query: 107 AGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGF 158 I VA+MK GE + E AYG G S P +PP A L++EVE+ F Sbjct: 87 KAWDIAVATMKVGELCRITCKPEYAYGSAG--SPPKIPPNATLVFEVELFEF 136 >4TW8-A nrPDB Length = 235 Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 50/159 (31%), Positives = 73/159 (45%), Gaps = 15/159 (9%) Query: 48 DEKVSKQIIKEGHGSK-PSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKEL 106 DE V K I +EG G++ P F+HY W + KF+ + + LGK + + Sbjct: 10 DEGVLKVIKREGTGTEMPMIGDRVFVHYTGWLLDGT-KFDSSLDRKDKFSFDLGK-GEVI 67 Query: 107 AGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETKEGKA 166 I +A+MK GE + E AYG G S P +PP A L++EVE+ F Sbjct: 68 KAWDIAIATMKVGEVCHITCKPEYAYGSAG--SPPKIPPNATLVFEVELFEF-------K 118 Query: 167 RSDMTVEERIGAADRRKMDGNSLFKEEK---LEEAMQQY 202 D+T EE G R + G K + +E A++ Y Sbjct: 119 GEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGY 157 Score = 31.6 bits (70), Expect = 0.51, Method: Compositional matrix adjust. Identities = 22/77 (28%), Positives = 42/77 (54%), Gaps = 3/77 (3%) Query: 85 FEDTWHEQQPIELVLGK-EKKELA-GLAIGVASMKSGERALVHVGWELAYGKEGNFSFPN 142 ++D +Q+ + +G+ E +L GL + M+ GE ++V++ A+G G F Sbjct: 158 YKDKLFDQRELRFEIGEGENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKF-Q 216 Query: 143 VPPMADLLYEVEVIGFD 159 +PP A+L YE+ + F+ Sbjct: 217 IPPNAELKYELHLKSFE 233 >1Q1C-A nrPDB Length = 280 Score = 55.8 bits (133), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 50/159 (31%), Positives = 73/159 (45%), Gaps = 15/159 (9%) Query: 48 DEKVSKQIIKEGHGSK-PSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKEL 106 DE V K I +EG G++ P F+HY W + KF+ + + LGK + + Sbjct: 50 DEGVLKVIKREGTGTEMPMIGDRVFVHYTGWLLDGT-KFDSSLDRKDKFSFDLGK-GEVI 107 Query: 107 AGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETKEGKA 166 I +A+MK GE + E AYG G S P +PP A L++EVE+ F Sbjct: 108 KAWDIAIATMKVGEVCHITCKPEYAYGSAG--SPPKIPPNATLVFEVELFEF-------K 158 Query: 167 RSDMTVEERIGAADRRKMDGNSLFKEEK---LEEAMQQY 202 D+T EE G R + G K + +E A++ Y Sbjct: 159 GEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGY 197 Score = 34.7 bits (78), Expect = 0.071, Method: Compositional matrix adjust. Identities = 24/81 (29%), Positives = 45/81 (55%), Gaps = 3/81 (3%) Query: 85 FEDTWHEQQPIELVLGK-EKKELA-GLAIGVASMKSGERALVHVGWELAYGKEGNFSFPN 142 ++D +Q+ + +G+ E +L GL + M+ GE ++V++ A+G G F Sbjct: 198 YKDKLFDQRELRFEIGEGENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKF-Q 256 Query: 143 VPPMADLLYEVEVIGFDETKE 163 +PP A+L YE+ + F++ KE Sbjct: 257 IPPNAELKYELHLKSFEKAKE 277 >4DRJ-A nrPDB Length = 144 Score = 54.7 bits (130), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 39/112 (34%), Positives = 56/112 (50%), Gaps = 5/112 (4%) Query: 48 DEKVSKQIIKEGHGSK-PSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKEL 106 DE V K I +EG G++ P F+HY W + KF+ + + LGK + + Sbjct: 34 DEGVLKVIKREGTGTEMPMIGDRVFVHYTGWLLDGT-KFDSSLDRKDKFSFDLGK-GEVI 91 Query: 107 AGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGF 158 I +A+MK GE + E AYG G S P +PP A L++EVE+ F Sbjct: 92 KAWDIAIATMKVGEVCHITCKPEYAYGSAG--SPPKIPPNATLVFEVELFEF 141 >3B7X-A nrPDB Length = 134 Score = 54.3 bits (129), Expect = 8e-08, Method: Compositional matrix adjust. Identities = 32/111 (28%), Positives = 55/111 (49%), Gaps = 3/111 (2%) Query: 48 DEKVSKQIIKEGHGSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELA 107 D V K +I+EG G + ++ + Y + ++ F+ + + P + LG E L Sbjct: 25 DRGVLKDVIREGAGDLVAPDASVLVKYSGYLEHMDRPFDSNYFRKTPRLMKLG-EDITLW 83 Query: 108 GLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGF 158 G+ +G+ SM+ GE A AYG G P +PP +L+E+E++ F Sbjct: 84 GMELGLLSMRRGELARFLFKPNYAYGTLG--CPPLIPPNTTVLFEIELLDF 132 >5L1D-B nrPDB Length = 158 Score = 53.9 bits (128), Expect = 9e-08, Method: Compositional matrix adjust. Identities = 33/110 (30%), Positives = 57/110 (51%), Gaps = 5/110 (4%) Query: 51 VSKQIIKEGHGSK-PSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGL 109 V + I G G P K TC +HY +N + KF+ + +P + +GK++ + G Sbjct: 53 VEIETISPGDGRTFPKKGQTCVVHYTGMLQNGK-KFDSSRDRNKPFKFRIGKQEV-IKGF 110 Query: 110 AIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFD 159 G A M G+RA + ++AYG G+ +PP A L+++VE++ + Sbjct: 111 EEGAAQMSLGQRAKLTCTPDVAYGATGHPGV--IPPNATLIFDVELLNLE 158 >2LGO-A nrPDB Length = 130 Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 33/111 (29%), Positives = 60/111 (54%), Gaps = 5/111 (4%) Query: 47 LDEKVSKQIIKEGHG-SKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKE 105 + ++ K+++ G G +KP +HY + + F+ + +P + LG + Sbjct: 22 MSAQLEKKVLTPGDGVTKPQAGKKVTVHYDGRFPDGKQ-FDSSRSRGKPFQFTLG-AGEV 79 Query: 106 LAGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVI 156 + G GVA+M GE+AL + ++LAYG+ G P +PP A L++EVE++ Sbjct: 80 IKGWDQGVATMTLGEKALFTIPYQLAYGERGY--PPVIPPKATLVFEVELL 128 >2ND5-A nrPDB Length = 111 Score = 53.1 bits (126), Expect = 2e-07, Method: Composition-based stats. Identities = 33/110 (30%), Positives = 59/110 (53%), Gaps = 5/110 (4%) Query: 51 VSKQIIKEGHGSK-PSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGL 109 V + I G G P + TC +HY ++ + KF+ + +P + +LGK++ + G Sbjct: 6 VQVETISPGDGRTFPKRGQTCVVHYTGMLEDGK-KFDSSRDRNKPFKFMLGKQEV-IRGW 63 Query: 110 AIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFD 159 GVA M G+RA + + + AYG G+ +PP A L+++VE++ + Sbjct: 64 EEGVAQMSVGQRAKLTISPDYAYGATGHPGI--IPPHATLVFDVELLKLE 111 >5T9S-F nrPDB Length = 108 Score = 52.8 bits (125), Expect = 2e-07, Method: Composition-based stats. Identities = 35/111 (31%), Positives = 58/111 (52%), Gaps = 7/111 (6%) Query: 51 VSKQIIKEGHGSK-PSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGL 109 V + I G G P K TC +HY +N + KF+ + +P + +GK++ + G Sbjct: 3 VEIETISPGDGRTFPKKGQTCVVHYTGMLQNGK-KFDSSRDRNKPFKFRIGKQEV-IKGF 60 Query: 110 AIGVASMKSGERALVHVGWELAYGKEGNFSFPNV-PPMADLLYEVEVIGFD 159 G A M G+RA + ++AYG G+ P V PP A L+++VE++ + Sbjct: 61 EEGAAQMSLGQRAKLTCTPDVAYGATGH---PGVIPPNATLIFDVELLNLE 108 >3O5D-A nrPDB Length = 264 Score = 52.0 bits (123), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 36/112 (32%), Positives = 56/112 (50%), Gaps = 5/112 (4%) Query: 48 DEKVSKQIIKEGHGSK-PSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKEL 106 D V K + + G+G + P ++HY+ N + KF+ + +P LGK + + Sbjct: 34 DRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGK-KFDSSHDRNEPFVFSLGK-GQVI 91 Query: 107 AGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGF 158 IGVA+MK GE + E AYG G S P +P A L +E+E++ F Sbjct: 92 KAWDIGVATMKKGEICHLLCKPEYAYGSAG--SLPKIPSNATLFFEIELLDF 141 >4R0X-A nrPDB Length = 122 Score = 51.6 bits (122), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 36/112 (32%), Positives = 56/112 (50%), Gaps = 5/112 (4%) Query: 48 DEKVSKQIIKEGHGSK-PSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKEL 106 D V K + + G+G + P ++HY+ N + KF+ + +P LGK + + Sbjct: 12 DRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGK-KFDSSHDRNEPFVFSLGK-GQVI 69 Query: 107 AGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGF 158 IGVA+MK GE + E AYG G S P +P A L +E+E++ F Sbjct: 70 KAWDIGVATMKKGEICHLLCKPEYAYGSAG--SLPGIPSNATLFFEIELLDF 119 >3O5E-A nrPDB Length = 144 Score = 51.6 bits (122), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 36/112 (32%), Positives = 56/112 (50%), Gaps = 5/112 (4%) Query: 48 DEKVSKQIIKEGHGSK-PSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKEL 106 D V K + + G+G + P ++HY+ N + KF+ + +P LGK + + Sbjct: 34 DRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGK-KFDSSHDRNEPFVFSLGK-GQVI 91 Query: 107 AGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGF 158 IGVA+MK GE + E AYG G S P +P A L +E+E++ F Sbjct: 92 KAWDIGVATMKKGEICHLLCKPEYAYGSAG--SLPKIPSNATLFFEIELLDF 141 >6B4P-A nrPDB Length = 127 Score = 50.4 bits (119), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 35/113 (30%), Positives = 59/113 (52%), Gaps = 7/113 (6%) Query: 48 DEKVSKQIIKEGHGS-KPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKEL 106 D+++ K+II G +P S +HY T S KF+ + QP LGK + + Sbjct: 19 DQRLKKKIITAGSSDEQPPIGSKVSVHYTG-TLTSGKKFDSSLDRGQPFVFTLGK-GEVI 76 Query: 107 AGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPN-VPPMADLLYEVEVIGF 158 G +GV SMK GE++ + + AY GN + P +P + L++E+E++ + Sbjct: 77 RGWDLGVKSMKKGEKSYFEIPSDYAY---GNNAIPGLIPANSTLMFEIELLSW 126 >3JXV-A nrPDB Length = 356 Score = 48.9 bits (115), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 34/112 (30%), Positives = 58/112 (51%), Gaps = 2/112 (1%) Query: 48 DEKVSKQIIKEGHG-SKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKEL 106 D+K+ K+++KE G +P++ + + ++ + EQ+P E E+ + Sbjct: 243 DKKILKKVLKEXEGYERPNEGAVVTVKITGKLQDGTVFLKKGHDEQEPFEFKT-DEEAVI 301 Query: 107 AGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGF 158 GL V +MK GE ALV + E AYG + VPP + ++YEVE++ F Sbjct: 302 EGLDRAVLNMKKGEVALVTIPPEYAYGSTESKQDAIVPPNSTVIYEVELVSF 353 Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust. Identities = 28/92 (30%), Positives = 47/92 (51%), Gaps = 4/92 (4%) Query: 72 LHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIGVASMKSGERALVHVGWELA 131 +HY T KF+ + + LG + + + G G+ +MK GE AL + ELA Sbjct: 35 VHYTG-TLLDGKKFDSSRDRDDTFKFKLG-QGQVIKGWDQGIKTMKKGENALFTIPPELA 92 Query: 132 YGKEGNFSFPNVPPMADLLYEVEVIGFDETKE 163 YG+ G S P +P A L ++VE++ + ++ Sbjct: 93 YGESG--SPPTIPANATLQFDVELLSWTSVRD 122 Score = 32.0 bits (71), Expect = 0.45, Method: Compositional matrix adjust. Identities = 32/122 (26%), Positives = 55/122 (45%), Gaps = 14/122 (11%) Query: 48 DEKVSKQIIKEGHG-SKPSKYSTCFLHYRAWTKNSQHKFED--TWHEQQPIELVLGKEKK 104 D + K+I+KEG P F+ Y A + ED + + +E + K+ Sbjct: 126 DGGIFKKILKEGDKWENPKDPDEVFVKYEA-------RLEDGTVVSKSEGVEFTV-KDGH 177 Query: 105 ELAGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPN---VPPMADLLYEVEVIGFDET 161 LA V +MK GE+ L+ V + +G+ G + VPP A L+ ++E++ + Sbjct: 178 LCPALAKAVKTMKKGEKVLLAVKPQYGFGEMGRPAAGEGGAVPPNASLVIDLELVSWKTV 237 Query: 162 KE 163 E Sbjct: 238 TE 239 >1R9H-A nrPDB Length = 135 Score = 47.8 bits (112), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 37/109 (33%), Positives = 53/109 (48%), Gaps = 5/109 (4%) Query: 48 DEKVSKQIIKEGHGS-KPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKEL 106 D V K I KEG G KP+ +T +HY +N KF+ + LG+ + Sbjct: 13 DGGVLKLIKKEGQGVVKPTTGTTVKVHYVGTLENGT-KFDSSRDRGDQFSFNLGR-GNVI 70 Query: 107 AGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEV 155 G +GVA+M GE A + + YG G S P +P A L++EVE+ Sbjct: 71 KGWDLGVATMTKGEVAEFTIRSDYGYGDAG--SPPKIPGGATLIFEVEL 117 >4GIV-A nrPDB Length = 209 Score = 47.4 bits (111), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 32/106 (30%), Positives = 47/106 (44%), Gaps = 14/106 (13%) Query: 56 IKEGHGSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAI---- 111 + EG G++ T +HY W + Q KF + P VLG G+ I Sbjct: 111 LTEGSGAEARAGQTVSVHYTGWLTDGQ-KFGSSKDRNDPFAFVLG------GGMVIKGWD 163 Query: 112 -GVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVI 156 GV MK G + + +L YG G +PP A L++EVE++ Sbjct: 164 EGVQGMKVGGVRRLTIPPQLGYGARGAGGV--IPPNATLVFEVELL 207 >3IHZ-A nrPDB Length = 126 Score = 47.0 bits (110), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 34/116 (29%), Positives = 59/116 (50%), Gaps = 6/116 (5%) Query: 48 DEKVSKQIIKEGHGSK---PSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKK 104 D V K I+++G G + P K + +HY ++S F+ + P + LG + + Sbjct: 14 DGGVVKTILRKGEGGEENAPKKGNEVTVHYVGKLESSGKVFDSSRERNVPFKFHLG-QGE 72 Query: 105 ELAGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDE 160 + G I VASM E+ V + + YG+EG ++P + L++E+E+I F E Sbjct: 73 VIKGWDICVASMTKNEKCSVRLDSKYGYGEEG--CGESIPGNSVLIFEIELISFRE 126 >5JHE-A nrPDB Length = 397 Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 34/132 (25%), Positives = 65/132 (49%), Gaps = 5/132 (3%) Query: 178 AADRRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMA-LAVKNPCHLNI 236 AA+ K G LFK++ A +Y ++ Y+ + K +++ + +K +LN+ Sbjct: 243 AANIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFINLKMKIYLNL 302 Query: 237 AACLIKLKRYDEAIGHCNIVL----TEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQK 292 + L L+RYD+AI + +L KA +RRG + + ++D A D+ ++ Sbjct: 303 SLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYIFCKE 362 Query: 293 YAPDDKAIRREL 304 PDD+ I + + Sbjct: 363 KNPDDEVIEQRI 374 >4QT3-A nrPDB Length = 134 Score = 46.2 bits (108), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 34/119 (28%), Positives = 61/119 (51%), Gaps = 6/119 (5%) Query: 48 DEKVSKQIIK---EGHGSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKK 104 D V K I+K EG + P K + +HY +++ F+ ++ P + L ++ + Sbjct: 11 DGGVIKTILKKGDEGEENIPKKGNEVTVHYVGKLESTGKVFDSSFDRNVPFKFHL-EQGE 69 Query: 105 ELAGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETKE 163 + G I V+SM+ E+ LV + YG EG ++P + LL+E+E++ F E +E Sbjct: 70 VIKGWDICVSSMRKNEKCLVRIESMYGYGDEG--CGESIPGNSVLLFEIELLSFRELEE 126 >2Y78-A nrPDB Length = 133 Score = 46.2 bits (108), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 32/106 (30%), Positives = 48/106 (45%), Gaps = 14/106 (13%) Query: 56 IKEGHGSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAI---- 111 + EG G++ T +HY W + Q KF+ + P VLG G+ I Sbjct: 35 LTEGSGAEARAGQTVSVHYTGWLTDGQ-KFDSSKDRNDPFAFVLG------GGMVIKGWD 87 Query: 112 -GVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVI 156 GV MK G + + +L YG G +PP A L++EVE++ Sbjct: 88 EGVQGMKVGGVRRLTIPPQLGYGARGAGGV--IPPNATLVFEVELL 131 >6FO1-G nrPDB Length = 665 Score = 46.2 bits (108), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 35/119 (29%), Positives = 52/119 (43%), Gaps = 17/119 (14%) Query: 186 GNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAACLIKLKR 245 GN FKE K E A++ Y IA G + + P N A +K+++ Sbjct: 289 GNGFFKEGKYERAIECYTRGIAADGANALL---------------PA--NRAMAYLKIQK 331 Query: 246 YDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPDDKAIRREL 304 Y+EA C + + KA RRG A+ LG+++ A+ DF P +K EL Sbjct: 332 YEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTEL 390 Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust. Identities = 37/141 (26%), Positives = 63/141 (44%), Gaps = 24/141 (17%) Query: 186 GNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPC-HLNIAACLIKLK 244 GN FK+ K +EA+ Y + D + NP N A+ +LK Sbjct: 140 GNKYFKQGKYDEAIDCYTKGMD--ADPY----------------NPVLPTNRASAYFRLK 181 Query: 245 RYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPDDKAIRREL 304 ++ A CN+ + KA RRG A+ L +++ A+ D+ + + P++ EL Sbjct: 182 KFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNEL 241 Query: 305 R----ALAEQEKALYQKQKEM 321 R ALA +E + Y K+ ++ Sbjct: 242 RKISQALASKENS-YPKEADI 261 >2L2S-A nrPDB Length = 117 Score = 45.4 bits (106), Expect = 3e-05, Method: Composition-based stats. Identities = 31/101 (30%), Positives = 47/101 (46%), Gaps = 4/101 (3%) Query: 56 IKEGHGSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIGVAS 115 + EG G++ T +HY W + Q KF+ + P VLG + G GV Sbjct: 19 LTEGSGAEARAGQTVSVHYTGWLTDGQ-KFDSSKDRNDPFAFVLGG-GMVIKGWDEGVQG 76 Query: 116 MKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVI 156 MK G + + +L YG G +PP A L++EVE++ Sbjct: 77 MKVGGVRRLTIPPQLGYGARGAGGV--IPPNATLVFEVELL 115 >4I2W-A nrPDB Length = 961 Score = 45.4 bits (106), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 48/181 (26%), Positives = 84/181 (46%), Gaps = 20/181 (11%) Query: 175 RIGAADRRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHL 234 R+ A+ + +GN+ K++ +A + Y A+ D +D AL + + Sbjct: 4 RVQTAEEIRDEGNAAVKDQDYIKADELYTEALQLTTD----------EDKAL--RPVLYR 51 Query: 235 NIAACLIKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYA 294 N A +K ++ A C L + + KALFRR A+ +LG + A D ++A + + Sbjct: 52 NRAMARLKRDDFEGAQSDCTKALEFDGADVKALFRRSLAREQLGNVGPAFQDAKEALRLS 111 Query: 295 PDDKAIRRELRALA-------EQEKALYQKQKEMYKGIFKGK-DEGGAKSKSLFWLIVLW 346 P+DK I L+ L +Q +L K +M K F+G+ + K +L L+VL Sbjct: 112 PNDKGIVEVLQRLVKANNDKIKQTTSLANKVTDMEKLAFRGEAKDTEQKMTALNNLLVLC 171 Query: 347 Q 347 + Sbjct: 172 R 172 >5B8I-C nrPDB Length = 130 Score = 44.3 bits (103), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 40/127 (31%), Positives = 65/127 (51%), Gaps = 25/127 (19%) Query: 51 VSKQIIKEGHG-SKPSKYSTCFLHYRAW----TKNSQH----KFEDTWHEQQPIELVLGK 101 V+K+I+KEG+G KP K ++YR +K S+H KF+ T E+ + +G Sbjct: 13 VTKKILKEGNGVDKPVKGDDIVMNYRGCLYDSSKPSEHFMGRKFDST-EERGEFKTKIG- 70 Query: 102 EKKELAGLAI-----GVASMKSGERALVHVGWELAYGKEGNFSFPN-VPPMADLLYEVEV 155 G+ I V M GE++++ + + AYG G FP +PP A L++EVE+ Sbjct: 71 -----IGVVIRGWDEAVLQMSLGEKSILTITDDYAYGARG---FPGLIPPHATLVFEVEL 122 Query: 156 IGFDETK 162 G + + Sbjct: 123 KGINSKR 129 >1Q6H-A nrPDB Length = 224 Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 26/103 (25%), Positives = 54/103 (52%), Gaps = 7/103 (6%) Query: 54 QIIKEGHGSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIGV 113 Q+++ G G P T ++Y+ + + F++++ +P+ L + G G+ Sbjct: 126 QVVEAGKGEAPKDSDTVVVNYKGTLIDGKE-FDNSYTRGEPLSFRL---DGVIPGWTEGL 181 Query: 114 ASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVI 156 ++K G + + + ELAYGK G P +PP + L+++VE++ Sbjct: 182 KNIKKGGKIKLVIPPELAYGKAG---VPGIPPNSTLVFDVELL 221 >1YAT-A nrPDB Length = 113 Score = 42.7 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 31/115 (26%), Positives = 56/115 (48%), Gaps = 7/115 (6%) Query: 44 AEVLDEKVSKQIIKEGHGSK-PSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKE 102 +EV++ V I G G+ P +HY +N Q KF+ + P + +G Sbjct: 1 SEVIEGNVKIDRISPGDGATFPKTGDLVTIHYTGTLENGQ-KFDSSVDRGSPFQCNIGV- 58 Query: 103 KKELAGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPN-VPPMADLLYEVEVI 156 + + G +G+ + GE+A + + AYG G FP +PP + L+++VE++ Sbjct: 59 GQVIKGWDVGIPKLSVGEKARLTIPGPYAYGPRG---FPGLIPPNSTLVFDVELL 110 >5HWB-A nrPDB Length = 115 Score = 42.4 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 31/114 (27%), Positives = 56/114 (49%), Gaps = 7/114 (6%) Query: 51 VSKQIIKEGHGSK-PSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGL 109 V+K++ G+G P K +HY + KF+ + +P + +G + + G Sbjct: 6 VTKELKSPGNGVDFPKKGDFVTIHYTGRLTDGS-KFDSSVDRNEPFQTQIGT-GRVIKGW 63 Query: 110 AIGVASMKSGERALVHVGWELAYGKEGNFSFPNV-PPMADLLYEVEVIGFDETK 162 GV M GE+A++ + + YG G FP V P + L++EVE++G + + Sbjct: 64 DEGVPQMSLGEKAVLTITPDYGYGARG---FPPVIPGNSTLIFEVELLGINNKR 114 >5I7P-A nrPDB Length = 161 Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust. Identities = 39/151 (25%), Positives = 68/151 (45%), Gaps = 14/151 (9%) Query: 51 VSKQIIKEGHG-SKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGL 109 V + I G G + P + T +HY ++ + KF+ + +P + +LGK++ + G Sbjct: 2 VQVETISPGDGRTFPKRGQTAVVHYTGMLEDGK-KFDSSRDRNKPFKFMLGKQEV-IRGW 59 Query: 110 AIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIG-----FDETKEG 164 GVA M G+RA + + + AYG+ VP D+ V+ + ET +G Sbjct: 60 EEGVAQMSVGQRAKLTISPDYAYGQYDENLVQRVP--KDVFMGVDELQVGMRFLAETDQG 117 Query: 165 KARSDMTVEERIGAADRRKMDGNSLFKEEKL 195 ++T E D +DGN + + L Sbjct: 118 PVPVEITAVED----DHVVVDGNHMLAGQNL 144 >5HUA-A nrPDB Length = 115 Score = 39.7 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 7/115 (6%) Query: 44 AEVLDEKVSKQIIKEGHGSK-PSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKE 102 +E ++ V + G G P + +HY +N Q KF+ + P + +G Sbjct: 3 SETIEGGVKIDRLSPGDGKTFPKQGDLVTIHYTGTLENGQ-KFDSSVDRGSPFQCNIGV- 60 Query: 103 KKELAGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPN-VPPMADLLYEVEVI 156 + + G G+ + GE+A + + AYG G FP +PP A L+++VE++ Sbjct: 61 GQVIKGWDAGIPKLSVGEKARLTIPGPYAYGPRG---FPGLIPPNATLIFDVELL 112 >5I7Q-A nrPDB Length = 162 Score = 39.3 bits (90), Expect = 0.003, Method: Compositional matrix adjust. Identities = 25/84 (29%), Positives = 44/84 (52%), Gaps = 3/84 (3%) Query: 51 VSKQIIKEGHG-SKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGL 109 V + I G G + P + T +HY ++ + KF+ + +P + +LGK++ + G Sbjct: 2 VQVETISPGDGRTFPKRGQTAVVHYTGMLEDGK-KFDSSRDRNKPFKFMLGKQEV-IRGW 59 Query: 110 AIGVASMKSGERALVHVGWELAYG 133 GVA M G+RA + + + AYG Sbjct: 60 EEGVAQMSVGQRAKLTISPDYAYG 83 >5JJT-A nrPDB Length = 479 Score = 39.3 bits (90), Expect = 0.003, Method: Compositional matrix adjust. Identities = 34/139 (24%), Positives = 58/139 (41%), Gaps = 20/139 (14%) Query: 176 IGAADRRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLN 235 + A+ K N FK K A+ Y AI ++ ++ N Sbjct: 6 VSRAEEFKSQANEAFKGHKYSSAIDLYTKAIELNSNNAVYWA-----------------N 48 Query: 236 IAACLIKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAP 295 A KL+ Y AI + + + + K +RRG A +G+ A DF++ ++ +P Sbjct: 49 RAFAHTKLEEYGSAIQDASKAIEVDSRYSKGYYRRGAAYLAMGKFKDALKDFQQVKRLSP 108 Query: 296 DDKAIRRELRALAEQEKAL 314 +D R+L+ E EKA+ Sbjct: 109 NDPDATRKLK---ECEKAV 124 >1JVW-A nrPDB Length = 167 Score = 38.1 bits (87), Expect = 0.006, Method: Compositional matrix adjust. Identities = 30/122 (24%), Positives = 56/122 (45%), Gaps = 9/122 (7%) Query: 54 QIIKEGHGSK-PSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIG 112 Q I G G + P+ C +HY ++ F+ + +P + + + G Sbjct: 42 QRIARGSGKRAPAIDDKCEVHYTGRLRDGT-VFDSSRERGKPTTF---RPNEVIKGWTEA 97 Query: 113 VASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETKEGKARSDMTV 172 + M+ G+R + + ++LAYG G +PP + L ++VE+I + GK R+ V Sbjct: 98 LQLMREGDRWRLFIPYDLAYGVTGGGGM--IPPYSPLEFDVELISIKDG--GKGRTAEEV 153 Query: 173 EE 174 +E Sbjct: 154 DE 155 >2MPH-A nrPDB Length = 224 Score = 37.0 bits (84), Expect = 0.014, Method: Compositional matrix adjust. Identities = 37/133 (27%), Positives = 59/133 (44%), Gaps = 14/133 (10%) Query: 38 PKVDSEAEVLDE---KVSKQIIKEGHGSK-PSK-------YSTCFLHYRAWTKNSQHKFE 86 PK E LDE K +K ++K+G + P K Y+ + N Q + Sbjct: 95 PKETKSEETLDEGPPKYTKSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAK 154 Query: 87 DTWHEQQPIELVLGKEKKELAGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPM 146 +P+ +G K + G + +M GE+A + + E AYGK+G +PP Sbjct: 155 KK-KNAKPLSFKVG-VGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQPD-AKIPPN 211 Query: 147 ADLLYEVEVIGFD 159 A L +EVE++ D Sbjct: 212 AKLTFEVELVDID 224 >2PBC-A nrPDB Length = 102 Score = 35.8 bits (81), Expect = 0.026, Method: Composition-based stats. Identities = 28/105 (26%), Positives = 49/105 (46%), Gaps = 4/105 (3%) Query: 59 GHGSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIGVASMKS 118 G K K +HY ++ +F+ + + QP LG + + G G+ M Sbjct: 1 GSPIKSRKGDVLHMHYTGKLEDGT-EFDSSLPQNQPFVFSLGT-GQVIKGWDQGLLGMCE 58 Query: 119 GERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETKE 163 GE+ + + EL YG+ G + P +P A L++EVE++ + E Sbjct: 59 GEKRKLVIPSELGYGERG--APPKIPGGATLVFEVELLKIERRTE 101 >5D75-A nrPDB Length = 124 Score = 35.4 bits (80), Expect = 0.038, Method: Compositional matrix adjust. Identities = 20/56 (35%), Positives = 31/56 (55%), Gaps = 1/56 (1%) Query: 104 KELAGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFD 159 K + G + +M GE+A + + E AYGK+G +PP A L +EVE++ D Sbjct: 62 KVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQPD-AKIPPNAKLTFEVELVDID 116 >5AEM-A nrPDB Length = 447 Score = 35.4 bits (80), Expect = 0.038, Method: Compositional matrix adjust. Identities = 43/181 (23%), Positives = 72/181 (39%), Gaps = 27/181 (14%) Query: 160 ETKEGKARSDMTVEERIGAADRRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYG 219 + E R+D+ V ER+ N + K++ A A +GD ++QL G Sbjct: 15 QANEAFVRNDLQVAERLF---------NEVIKKDARNFA------AYETLGD--IYQLQG 57 Query: 220 KYQDMALAVKNPCHLN---------IAACLIKLKRYDEAIGHCNIVLTEEEKNPKALFRR 270 + D + HLN +A L +AI + V++ ++++RR Sbjct: 58 RLNDCCNSWFLAAHLNASDWEFWKIVAILSADLDHVRQAIYCFSRVISLNPMEWESIYRR 117 Query: 271 GKAKAELGQMDSARDDFRKAQKYAPDDKAIRRELRALAEQEKALYQKQKEMYKGIFKGKD 330 + GQ+ A D F++ Y P D I REL L + + E+Y +F Sbjct: 118 SMLYKKTGQLARALDGFQRLYMYNPYDANILRELAILYVDYDRI-EDSIELYMKVFNANV 176 Query: 331 E 331 E Sbjct: 177 E 177 >4NNR-A nrPDB Length = 142 Score = 35.4 bits (80), Expect = 0.038, Method: Compositional matrix adjust. Identities = 27/101 (26%), Positives = 48/101 (47%), Gaps = 4/101 (3%) Query: 63 KPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIGVASMKSGERA 122 K K +HY ++ +F+ + + QP LG + + G G+ M GE+ Sbjct: 45 KSRKGDVLHMHYTGKLEDGT-EFDSSLPQNQPFVFSLGT-GQVIKGWDQGLLGMCEGEKR 102 Query: 123 LVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETKE 163 + + EL YG+ G + P +P A L++EVE++ + E Sbjct: 103 KLVIPSELGYGERG--APPKIPGGATLVFEVELLKIERRTE 141 >4JA9-A nrPDB Length = 488 Score = 35.0 bits (79), Expect = 0.058, Method: Compositional matrix adjust. Identities = 30/132 (22%), Positives = 53/132 (40%), Gaps = 17/132 (12%) Query: 167 RSDMTVEERIGAADRRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMAL 226 R + E + A+ K N FK + E A++ Y AI + ++ YG Sbjct: 5 RDEPPAEGTLKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIY--YG------- 55 Query: 227 AVKNPCHLNIAACLIKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDD 286 N + ++ + Y A+G + ++K K +RR + LG+ +A D Sbjct: 56 --------NRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRD 107 Query: 287 FRKAQKYAPDDK 298 + K P+DK Sbjct: 108 YETVVKVKPNDK 119 >3UQI-A nrPDB Length = 108 Score = 34.7 bits (78), Expect = 0.066, Method: Composition-based stats. Identities = 26/94 (27%), Positives = 44/94 (46%), Gaps = 6/94 (6%) Query: 64 PSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIGVASMKSGERAL 123 P +HY + + F+ + +P +G+ + + G GVA M G+RA Sbjct: 17 PKAGQVAVVHYTGTLADGK-VFDSSRTRGKPFRFTVGR-GEVIRGWDEGVAQMSVGQRAK 74 Query: 124 VHVGWELAYGKEGNFSFPNV-PPMADLLYEVEVI 156 + + AYG G+ P V PP A L ++VE++ Sbjct: 75 LVCSPDYAYGSRGH---PGVIPPNATLTFDVELL 105 >4JM7-A nrPDB Length = 143 Score = 34.7 bits (78), Expect = 0.076, Method: Compositional matrix adjust. Identities = 18/41 (43%), Positives = 23/41 (56%), Gaps = 1/41 (2%) Query: 75 RAWTKNSQHKFEDTWHEQQPIELVLGK-EKKELAGLAIGVA 114 R TKN QHKF + HEQ+ IE + G+ KE A+G Sbjct: 52 RILTKNEQHKFNNFTHEQRKIEFLAGRFATKEAFSKALGTG 92 >5CXD-A nrPDB Length = 122 Score = 34.3 bits (77), Expect = 0.083, Method: Compositional matrix adjust. Identities = 18/41 (43%), Positives = 23/41 (56%), Gaps = 1/41 (2%) Query: 75 RAWTKNSQHKFEDTWHEQQPIELVLGK-EKKELAGLAIGVA 114 R TKN QHKF + HEQ+ IE + G+ KE A+G Sbjct: 31 RILTKNEQHKFNNFTHEQRKIEFLAGRFATKEAFSKALGTG 71 >4JYS-A nrPDB Length = 138 Score = 33.9 bits (76), Expect = 0.11, Method: Compositional matrix adjust. Identities = 32/120 (26%), Positives = 53/120 (44%), Gaps = 14/120 (11%) Query: 38 PKVDSEAEVLDEKVSKQIIKEGHGSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIEL 97 P V +E+ +L K +I +G G + ++HY+ T N T++ P ++ Sbjct: 7 PYVKTESGIL----YKDLI-DGEGDPIEEGDIVYIHYQGKTTNDFRIIHSTFNSIIPPKI 61 Query: 98 VLGK-EKKELAGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVI 156 G+ ++K + + V MK R V LAY PN P LLYE++V+ Sbjct: 62 RAGQYDQKHIRAIYEIVIGMKKHTRRQCVVPPHLAY--------PNHFPSQPLLYEIDVV 113 >4MSP-A nrPDB Length = 200 Score = 33.5 bits (75), Expect = 0.13, Method: Compositional matrix adjust. Identities = 24/88 (27%), Positives = 41/88 (46%), Gaps = 6/88 (6%) Query: 71 FLHYRAWTKNSQHKFEDTW--HEQQPIELVLGKEKKELAGLAIGVASMKSGERALVHVGW 128 +HY + + F T + QPI LG + L G G+ M GE+ + + Sbjct: 38 LVHYEGYLEKDGSLFHSTHKHNNGQPIWFTLGI-LEALKGWDQGLKGMCVGEKRKLIIPP 96 Query: 129 ELAYGKEGNFSFPNVPPMADLLYEVEVI 156 L YGKEG +PP + L++ ++++ Sbjct: 97 ALGYGKEGK---GKIPPESTLIFNIDLL 121 >4I9E-A nrPDB Length = 383 Score = 33.1 bits (74), Expect = 0.19, Method: Compositional matrix adjust. Identities = 43/170 (25%), Positives = 76/170 (44%), Gaps = 23/170 (13%) Query: 144 PPMADLLYEVE-----VIGFDETKEGKARSDMTVEER--IGAADR-RKMDGNSLFKEEKL 195 P ++DLL E++ + G E R +++R + A +K + +F ++++ Sbjct: 81 PRLSDLLLEIDKKQARLTGLLEYYFNFFRGMYELDQREYLSAIKFFKKAESKLIFVKDRI 140 Query: 196 EEA-----MQQ--YEMAIAYMGDDFMFQLYGKYQDM-ALAVKN-PCHLNIAACLIKLKRY 246 E+A M + Y M Y D+ Q Y Y++ A ++ CH A + LK+Y Sbjct: 141 EKAEFFFKMSESYYYMKQTYFSMDYARQAYEIYKEHEAYNIRLLQCHSLFATNFLDLKQY 200 Query: 247 DEAIGHCN--IVLTEEEKNP----KALFRRGKAKAELGQMDSARDDFRKA 290 ++AI H + E EK P + L+ G K Q + A F++A Sbjct: 201 EDAISHFQKAYSMAEAEKQPQLMGRTLYNIGLCKNSQSQYEDAIPYFKRA 250 >4DIP-A nrPDB Length = 125 Score = 32.3 bits (72), Expect = 0.31, Method: Compositional matrix adjust. Identities = 24/88 (27%), Positives = 41/88 (46%), Gaps = 6/88 (6%) Query: 71 FLHYRAWTKNSQHKFEDTW--HEQQPIELVLGKEKKELAGLAIGVASMKSGERALVHVGW 128 +HY + + F T + QPI LG + L G G+ M GE+ + + Sbjct: 36 LVHYEGYLEKDGSLFHSTHKHNNGQPIWFTLGI-LEALKGWDQGLKGMCVGEKRKLIIPP 94 Query: 129 ELAYGKEGNFSFPNVPPMADLLYEVEVI 156 L YGKEG +PP + L++ ++++ Sbjct: 95 ALGYGKEGKGK---IPPESTLIFNIDLL 119 >1Y0O-A nrPDB Length = 129 Score = 32.0 bits (71), Expect = 0.45, Method: Compositional matrix adjust. Identities = 27/109 (24%), Positives = 52/109 (47%), Gaps = 13/109 (11%) Query: 59 GHGSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPI-------ELVLGKEKKELAGLAI 111 G+G + K HY +N + F+ +++ +P+ E++ G ++ L + Sbjct: 22 GYGPEAVKGQLIKAHYVGKLENGK-VFDSSYNRGKPLTFRIGVGEVIKGWDQGILG--SD 78 Query: 112 GVASMKSGERALVHVGWELAYGKEGNFSFPN---VPPMADLLYEVEVIG 157 G+ M +G + + + ELAYG G +PP + LL+++E IG Sbjct: 79 GIPPMLTGGKRTLRIPPELAYGDRGAGCKGGSCLIPPASVLLFDIEYIG 127 >1XTP-A nrPDB Length = 254 Score = 31.2 bits (69), Expect = 0.68, Method: Compositional matrix adjust. Identities = 26/100 (26%), Positives = 43/100 (43%), Gaps = 8/100 (8%) Query: 47 LDEKVSKQIIKEGHGSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKEL 106 +D + S+ I G S+ C TKN K T +P++ +L + K+EL Sbjct: 77 VDIEGSRNFIASLPGHGTSRALDCGAGIGRITKNLLTKLYATTDLLEPVKHMLEEAKREL 136 Query: 107 AGLAIGVASMKSGERA--------LVHVGWELAYGKEGNF 138 AG+ +G + S E A L+ + W Y + +F Sbjct: 137 AGMPVGKFILASMETATLPPNTYDLIVIQWTAIYLTDADF 176 >4BF8-A nrPDB Length = 117 Score = 31.2 bits (69), Expect = 0.76, Method: Composition-based stats. Identities = 26/98 (26%), Positives = 45/98 (45%), Gaps = 6/98 (6%) Query: 59 GHGSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIGVASMKS 118 G G K + + Y KN K D + +P LG + + + G IGVA M Sbjct: 23 GKGPHAKKGTRVGMRYVGKLKNG--KVFDKNTKGKPFVFKLG-QGEVIKGWDIGVAGMAV 79 Query: 119 GERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVI 156 G + + AYGK+ + P +P ++L ++V+++ Sbjct: 80 GGERRIVIPAPYAYGKQ---ALPGIPANSELTFDVKLV 114 >6B85-J nrPDB Length = 223 Score = 31.2 bits (69), Expect = 0.84, Method: Compositional matrix adjust. Identities = 22/71 (30%), Positives = 36/71 (50%) Query: 234 LNIAACLIKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKY 293 L + + L KLKR DEA + + + A GK +LG++D A + ++KA + Sbjct: 119 LLLGSVLEKLKRLDEAAEAYKKAIELKPNDASAWKELGKVLEKLGRLDEAAEAYKKAIEL 178 Query: 294 APDDKAIRREL 304 P+D +EL Sbjct: 179 DPEDAEAWKEL 189 Score = 27.7 bits (60), Expect = 8.9, Method: Compositional matrix adjust. Identities = 31/112 (27%), Positives = 52/112 (46%), Gaps = 17/112 (15%) Query: 186 GNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAACLIKLKR 245 G+ L K ++L+EA + Y+ AI +D A A K + L KL R Sbjct: 122 GSVLEKLKRLDEAAEAYKKAIELKPND------------ASAWKE-----LGKVLEKLGR 164 Query: 246 YDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPDD 297 DEA + + ++ +A GK +LG++D A + ++KA + P+D Sbjct: 165 LDEAAEAYKKAIELDPEDAEAWKELGKVLEKLGRLDEAAEAYKKAIELDPND 216 >1A17-A nrPDB Length = 166 Score = 30.4 bits (67), Expect = 1.3, Method: Compositional matrix adjust. Identities = 28/120 (23%), Positives = 48/120 (40%), Gaps = 17/120 (14%) Query: 179 ADRRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAA 238 A+ K N FK + E A++ Y AI + ++ YG N + Sbjct: 13 AEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIY--YG---------------NRSL 55 Query: 239 CLIKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPDDK 298 ++ + Y A+G + ++K K +RR + LG+ +A D+ K P DK Sbjct: 56 AYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDK 115 >3PR3-A nrPDB Length = 597 Score = 29.6 bits (65), Expect = 2.0, Method: Compositional matrix adjust. Identities = 13/40 (32%), Positives = 22/40 (55%), Gaps = 2/40 (5%) Query: 61 GSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQ--PIELV 98 ++P Y+TC +++ N QH F H+ Q P+EL+ Sbjct: 407 NNQPIHYNTCQVYFGEPGTNGQHSFYQLIHQGQVIPVELI 446 >4I1A-A nrPDB Length = 391 Score = 29.3 bits (64), Expect = 2.6, Method: Compositional matrix adjust. Identities = 25/83 (30%), Positives = 36/83 (43%), Gaps = 7/83 (8%) Query: 232 CHLNIAACLIKLKRYDEAIGHCNIVLTEEEKN-----PKALFRRGKAKAELGQMDSARDD 286 H+NI C +LK Y +A H + L EK+ K LF +A+ + A Sbjct: 226 SHMNIGICYDELKEYKKASQHLILALEIFEKSKHSFLTKTLFTLTYVEAKQQNYNVALIY 285 Query: 287 FRKAQKYA--PDDKAIRRELRAL 307 FRK + A DDK + + L Sbjct: 286 FRKGRFIADKSDDKEYSAKFKIL 308 >4CGU-A nrPDB Length = 112 Score = 28.9 bits (63), Expect = 3.3, Method: Compositional matrix adjust. Identities = 23/75 (30%), Positives = 33/75 (44%), Gaps = 19/75 (25%) Query: 180 DRRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPC-HLNIAA 238 +++K GNSLFK+ EA+ Y+ Q + +NP + N A Sbjct: 6 EKQKEQGNSLFKQGLYREAVHCYD------------------QLITAQPQNPVGYSNKAM 47 Query: 239 CLIKLKRYDEAIGHC 253 LIKL Y +AI C Sbjct: 48 ALIKLGEYTQAIQMC 62 >4ODP-A nrPDB Length = 110 Score = 28.9 bits (63), Expect = 3.8, Method: Compositional matrix adjust. Identities = 18/51 (35%), Positives = 26/51 (50%), Gaps = 2/51 (3%) Query: 106 LAGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVI 156 + GL + + GE HV E AYG G+ +PP A L ++VEV+ Sbjct: 37 IPGLEEALEGREEGEAFQAHVPAEKAYGATGHPGI--IPPHATLDFQVEVV 85 >1U61-A nrPDB Length = 138 Score = 28.1 bits (61), Expect = 6.0, Method: Compositional matrix adjust. Identities = 23/79 (29%), Positives = 39/79 (49%), Gaps = 7/79 (8%) Query: 197 EAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLN-IAACLIKLKRYDEAIGHC-- 253 +A Q +A+AYMGD +++ Y +Y + P L+ + + K + + H Sbjct: 6 DAKQLNSLALAYMGDA-VYEQYIRYHLLQKGKVRPNQLHRLGTSFVSAKAQAKVVYHLLE 64 Query: 254 NIVLTEEEKNPKALFRRGK 272 LTEEE +A+ RRG+ Sbjct: 65 TAFLTEEE---EAVLRRGR 80 >6H3J-B nrPDB Length = 176 Score = 27.7 bits (60), Expect = 7.8, Method: Compositional matrix adjust. Identities = 15/48 (31%), Positives = 24/48 (50%), Gaps = 3/48 (6%) Query: 112 GVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFD 159 G+ +KSG + V L YG GN VP A L++E+ ++ + Sbjct: 132 GIPLLKSGGEIQLFVPAHLGYGSNGN---KTVPGGAVLIFEITLVSVN 176 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2IF4-A nrPDB 437 e-123 5MGX-E nrPDB 297 4e-81 1KT1-A nrPDB 269 1e-72 5OMP-A nrPDB 266 1e-71 1QZ2-A nrPDB 264 4e-71 2F4E-A nrPDB 256 1e-68 1Q1C-A nrPDB 183 2e-46 4TW8-A nrPDB 182 2e-46 4I2W-A nrPDB 168 3e-42 1IHG-A nrPDB 164 7e-41 3O5D-A nrPDB 162 2e-40 1ROT-A nrPDB 161 6e-40 4DRJ-A nrPDB 160 9e-40 2ND5-A nrPDB 158 3e-39 5I7P-A nrPDB 157 7e-39 4R0X-A nrPDB 157 9e-39 3O5E-A nrPDB 154 4e-38 5HWB-A nrPDB 153 9e-38 5HUA-A nrPDB 151 4e-37 1YAT-A nrPDB 150 8e-37 5T9S-F nrPDB 150 1e-36 1R9H-A nrPDB 149 1e-36 5JHE-A nrPDB 149 2e-36 2Y78-A nrPDB 148 3e-36 2L2S-A nrPDB 148 4e-36 5L1D-B nrPDB 147 6e-36 3IHZ-A nrPDB 143 1e-34 4GIV-A nrPDB 142 1e-34 4QT3-A nrPDB 142 3e-34 2LGO-A nrPDB 141 4e-34 6B4P-A nrPDB 140 8e-34 3B7X-A nrPDB 134 6e-32 3JXV-A nrPDB 131 5e-31 5B8I-C nrPDB 129 2e-30 6FO1-G nrPDB 123 1e-28 1Q6H-A nrPDB 102 3e-22 Sequences not found previously or not previously below threshold: 3UQI-A nrPDB 137 9e-33 5I7Q-A nrPDB 125 3e-29 4NNR-A nrPDB 116 1e-26 2PBC-A nrPDB 116 2e-26 5HW8-A nrPDB 112 2e-25 4BF8-A nrPDB 105 3e-23 2MPH-A nrPDB 101 4e-22 1Y0O-A nrPDB 101 5e-22 1JVW-A nrPDB 100 8e-22 3EY6-A nrPDB 100 2e-21 5D75-A nrPDB 99 3e-21 2D9F-A nrPDB 99 4e-21 5JJT-A nrPDB 97 1e-20 2MF9-A nrPDB 96 2e-20 2VCD-A nrPDB 93 2e-19 1FD9-A nrPDB 91 8e-19 4DIP-A nrPDB 91 9e-19 4MSP-A nrPDB 91 9e-19 4JA9-A nrPDB 89 3e-18 1A17-A nrPDB 79 3e-15 5XB0-A nrPDB 77 1e-14 2C2L-A nrPDB 67 8e-12 2Y4T-A nrPDB 66 2e-11 6H3J-B nrPDB 61 6e-10 2KFW-A nrPDB 60 2e-09 2K8I-A nrPDB 60 2e-09 2GW1-A nrPDB 59 5e-09 2LKN-A nrPDB 57 9e-09 6B85-J nrPDB 57 2e-08 4JYS-A nrPDB 56 3e-08 1IX5-A nrPDB 55 6e-08 4ODP-A nrPDB 52 4e-07 5LVV-A nrPDB 52 5e-07 5AEM-A nrPDB 50 1e-06 3PRA-A nrPDB 49 4e-06 5KHR-J nrPDB 47 9e-06 3PRB-A nrPDB 47 1e-05 5A01-A nrPDB 46 2e-05 4DT4-A nrPDB 46 2e-05 2M2A-A nrPDB 46 2e-05 5G04-F nrPDB 45 5e-05 5U9A-A nrPDB 45 5e-05 1W3B-A nrPDB 45 7e-05 2KR7-A nrPDB 44 1e-04 5FZQ-A nrPDB 42 3e-04 4CGU-A nrPDB 41 6e-04 5WQL-B nrPDB 41 8e-04 1HH8-A nrPDB 40 0.002 5NNP-A nrPDB 39 0.003 4JHR-A nrPDB 37 0.010 6C95-A nrPDB 37 0.010 6N3Q-F nrPDB 37 0.014 5DSE-A nrPDB 36 0.026 5ZYQ-A nrPDB 36 0.040 5OJ8-A nrPDB 35 0.053 5G04-X nrPDB 35 0.053 4I1A-A nrPDB 35 0.061 3NF1-A nrPDB 34 0.086 4UZY-A nrPDB 34 0.096 3CGM-A nrPDB 34 0.11 4HOQ-A nrPDB 33 0.16 6FUZ-A nrPDB 33 0.19 5OJF-A nrPDB 32 0.38 4I9E-A nrPDB 32 0.45 3ZFW-A nrPDB 32 0.61 5C3C-A nrPDB 31 0.89 1A3W-A nrPDB 31 0.97 5O09-1C nrPDB 31 1.1 1HXV-A nrPDB 31 1.2 5EFR-A nrPDB 30 1.4 2VNC-A nrPDB 30 1.4 4CI6-B nrPDB 30 2.0 1L1F-A nrPDB 30 2.3 6OGD-C nrPDB 29 2.5 4DWS-C nrPDB 29 2.5 6DHM-A nrPDB 29 2.8 6AF0-A nrPDB 29 2.8 6D6S-A nrPDB 29 3.5 3J9W-BF nrPDB 29 4.0 3HTX-A nrPDB 29 4.1 5FCL-A nrPDB 29 4.3 6EPE-S nrPDB 29 4.5 4G1T-A nrPDB 29 4.9 3WPZ-A nrPDB 28 6.1 3AHY-A nrPDB 28 7.4 3LZX-A nrPDB 28 7.7 >2IF4-A nrPDB Length = 338 Score = 437 bits (1123), Expect = e-123, Method: Composition-based stats. Identities = 338/338 (100%), Positives = 338/338 (100%) Query: 1 MDESLEHQTQTHDQESEIVTEGSAVVHSEPSQEGNVPPKVDSEAEVLDEKVSKQIIKEGH 60 MDESLEHQTQTHDQESEIVTEGSAVVHSEPSQEGNVPPKVDSEAEVLDEKVSKQIIKEGH Sbjct: 1 MDESLEHQTQTHDQESEIVTEGSAVVHSEPSQEGNVPPKVDSEAEVLDEKVSKQIIKEGH 60 Query: 61 GSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIGVASMKSGE 120 GSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIGVASMKSGE Sbjct: 61 GSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIGVASMKSGE 120 Query: 121 RALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETKEGKARSDMTVEERIGAAD 180 RALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETKEGKARSDMTVEERIGAAD Sbjct: 121 RALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETKEGKARSDMTVEERIGAAD 180 Query: 181 RRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAACL 240 RRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAACL Sbjct: 181 RRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAACL 240 Query: 241 IKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPDDKAI 300 IKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPDDKAI Sbjct: 241 IKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPDDKAI 300 Query: 301 RRELRALAEQEKALYQKQKEMYKGIFKGKDEGGAKSKS 338 RRELRALAEQEKALYQKQKEMYKGIFKGKDEGGAKSKS Sbjct: 301 RRELRALAEQEKALYQKQKEMYKGIFKGKDEGGAKSKS 338 >5MGX-E nrPDB Length = 290 Score = 297 bits (761), Expect = 4e-81, Method: Composition-based stats. Identities = 76/288 (26%), Positives = 126/288 (43%), Gaps = 13/288 (4%) Query: 51 VSKQIIKEG--HGSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAG 108 + K+ + G S+P K +H + +N E+ + LG + + Sbjct: 12 LRKKTLVPGPPGSSRPVKGQVVTVHLQTSLENGTR-----VQEEPELVFTLG-DCDVIQA 65 Query: 109 LAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETKEGKARS 168 L + V M GE A+V + YG +G P +PP A L EV + +G Sbjct: 66 LDLSVPLMDVGETAMVTADSKYCYGPQGRS--PYIPPHAALCLEVTL---KTAVDGPDLE 120 Query: 169 DMTVEERIGAADRRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAV 228 +T +ER+ A+R++ GN+ ++ A Y++AI + + + + L + Sbjct: 121 MLTGQERVALANRKRECGNAHYQRADFVLAANSYDLAIKAITSSAKVDMTFEEEAQLLQL 180 Query: 229 KNPCHLNIAACLIKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFR 288 K C N+AA +KL Y A+ C++VL + N KALFR+GK A+ G+ A R Sbjct: 181 KVKCLNNLAASQLKLDHYRAALRSCSLVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILR 240 Query: 289 KAQKYAPDDKAIRRELRALAEQEKALYQKQKEMYKGIFKGKDEGGAKS 336 A K P +K I EL L ++ A + +Y+ + AK Sbjct: 241 AALKLEPSNKTIHAELSKLVKKHAAQRSTETALYRKMLGNPSRLPAKC 288 >1KT1-A nrPDB Length = 457 Score = 269 bits (687), Expect = 1e-72, Method: Composition-based stats. Identities = 71/292 (24%), Positives = 138/292 (47%), Gaps = 12/292 (4%) Query: 48 DEKVSKQIIKEGHG-SKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKEL 106 D + ++ + G G S P++ + +H F+ + G++ Sbjct: 145 DGGIIRRTKRRGEGYSNPNEGARVQIHLEGRC--GGRVFDC---RDVAFTVGEGEDHDIP 199 Query: 107 AGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETKEGKA 166 G+ + M+ E+ ++H+G +G+ G F + P A+L+YEV + F++ KE Sbjct: 200 IGIDKALEKMQREEQCILHLGPRYGFGEAGKPKF-GIEPNAELIYEVTLKSFEKAKES-- 256 Query: 167 RSDMTVEERIGAADRRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMAL 226 +M +E++ A K G FK K +A+ QY ++++ + + L K + Sbjct: 257 -WEMDTKEKLEQAAIVKEKGTVYFKGGKYVQAVIQYGKIVSWL--EMEYGLSEKESKASE 313 Query: 227 AVKNPCHLNIAACLIKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDD 286 + LN+A C +KL+ Y +A+ C+ L + N K L+RRG+A+ + + +SA+ D Sbjct: 314 SFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGD 373 Query: 287 FRKAQKYAPDDKAIRRELRALAEQEKALYQKQKEMYKGIFKGKDEGGAKSKS 338 F K + P +KA R ++ ++ K ++ + Y +FK E AK ++ Sbjct: 374 FEKVLEVNPQNKAARLQIFMCQKKAKEHNERDRRTYANMFKKFAEQDAKEEA 425 Score = 158 bits (398), Expect = 5e-39, Method: Composition-based stats. Identities = 47/169 (27%), Positives = 70/169 (41%), Gaps = 18/169 (10%) Query: 31 SQEGNVPPKVDSEAEVL----DEKVSKQIIKEGHGSK-PSKYSTCFLHYRAWTKNSQHKF 85 + GN V + E + D V K + + GHG + P ++HY N + KF Sbjct: 9 NSRGNPAATVAEQGEDVTSKKDRGVLKIVKRVGHGEETPMIGDRVYVHYNGKLANGK-KF 67 Query: 86 EDTWHEQQPIELVLGKEKKELAGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPP 145 + + +P +GK + + IGVA+MK GE + E AYG G S P +P Sbjct: 68 DSSHDRNEPFVFSIGK-GQVIKAWDIGVATMKKGEICHLLCKPEYAYGATG--SLPKIPS 124 Query: 146 MADLLYEVEVIGFDETKEGKARSDMTVEERIGAADRRKMDGNSLFKEEK 194 A L +EVE++ F D+ E G R K G + Sbjct: 125 NATLFFEVELLDFK-------GEDL--LEDGGIIRRTKRRGEGYSNPNE 164 >5OMP-A nrPDB Length = 462 Score = 266 bits (679), Expect = 1e-71, Method: Composition-based stats. Identities = 71/292 (24%), Positives = 141/292 (48%), Gaps = 12/292 (4%) Query: 48 DEKVSKQIIKEGHG-SKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKEL 106 D + ++ ++G G S P++ +T +H F+ + G++ Sbjct: 150 DGGIIRRTKRKGEGYSNPNEGATVEIHLEGRC--GGRMFDC---RDVAFTVGEGEDHDIP 204 Query: 107 AGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETKEGKA 166 G+ + M+ E+ ++++G +G+ G F + P A+L+YEV + F++ KE Sbjct: 205 IGIDKALEKMQREEQCILYLGPRYGFGEAGKPKF-GIEPNAELIYEVTLKSFEKAKES-- 261 Query: 167 RSDMTVEERIGAADRRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMAL 226 +M +E++ A K G FK K +A+ QY ++++ + + L K + Sbjct: 262 -WEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWL--EMEYGLSEKESKASE 318 Query: 227 AVKNPCHLNIAACLIKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDD 286 + LN+A C +KL+ Y +A+ C+ L + N K L+RRG+A+ + + +SA+ D Sbjct: 319 SFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGD 378 Query: 287 FRKAQKYAPDDKAIRRELRALAEQEKALYQKQKEMYKGIFKGKDEGGAKSKS 338 F K + P +KA R ++ ++ K ++ + +Y +FK E AK ++ Sbjct: 379 FEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAKEEA 430 Score = 155 bits (392), Expect = 2e-38, Method: Composition-based stats. Identities = 46/177 (25%), Positives = 73/177 (41%), Gaps = 14/177 (7%) Query: 19 VTEGSAVVHSEPSQEGNVPPKVDSEAEVLDEKVSKQIIKEGHGSK-PSKYSTCFLHYRAW 77 +T ++E S V + + D V K + + G+G + P ++HY+ Sbjct: 6 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 65 Query: 78 TKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIGVASMKSGERALVHVGWELAYGKEGN 137 N + KF+ + +P LGK + + IGVA+MK GE + E AYG G Sbjct: 66 LSNGK-KFDSSHDRNEPFVFSLGK-GQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAG- 122 Query: 138 FSFPNVPPMADLLYEVEVIGFDETKEGKARSDMTVEERIGAADRRKMDGNSLFKEEK 194 S P +P A L +E+E++ F D+ E G R K G + Sbjct: 123 -SLPKIPSNATLFFEIELLDFK-------GEDLF--EDGGIIRRTKRKGEGYSNPNE 169 >1QZ2-A nrPDB Length = 336 Score = 264 bits (675), Expect = 4e-71, Method: Composition-based stats. Identities = 79/296 (26%), Positives = 154/296 (52%), Gaps = 18/296 (6%) Query: 48 DEKVSKQIIKEGHG-SKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGK-EKKE 105 D + ++I G G +KP++ + + + ++D +Q+ + +G+ E + Sbjct: 24 DGGIIRRIQTRGEGYAKPNEGAIVEVALEGY-------YKDKLFDQRELRFEIGEGENLD 76 Query: 106 LA-GLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETKEG 164 L GL + M+ GE ++V++ A+G G F +PP A+L YE+ + F++ KE Sbjct: 77 LPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKF-QIPPNAELKYELHLKSFEKAKES 135 Query: 165 KARSDMTVEERIGAADRRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDM 224 +M EE++ + K G FKE K ++A+ QY+ ++++ ++ + Sbjct: 136 ---WEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWL--EYESSFSNEEAQK 190 Query: 225 ALAVKNPCHLNIAACLIKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSAR 284 A A++ HLN+A C +KL+ + AI CN L + N K LFRRG+A + + AR Sbjct: 191 AQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFELAR 250 Query: 285 DDFRKAQKYAPDDKAIRRELRALAEQEKALYQKQKEMYKGIFK--GKDEGGAKSKS 338 DF+K + P++KA + +L ++ + ++K++Y +F+ ++E AK+++ Sbjct: 251 ADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMFERLAEEENKAKAEA 306 Score = 32.4 bits (72), Expect = 0.32, Method: Composition-based stats. Identities = 10/52 (19%), Positives = 19/52 (36%), Gaps = 3/52 (5%) Query: 173 EERIGAADRRKMDGNSLFKEEK---LEEAMQQYEMAIAYMGDDFMFQLYGKY 221 EE G R + G K + +E A++ Y + + F++ Sbjct: 22 EEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKDKLFDQRELRFEIGEGE 73 >2F4E-A nrPDB Length = 180 Score = 256 bits (653), Expect = 1e-68, Method: Composition-based stats. Identities = 180/180 (100%), Positives = 180/180 (100%) Query: 1 MDESLEHQTQTHDQESEIVTEGSAVVHSEPSQEGNVPPKVDSEAEVLDEKVSKQIIKEGH 60 MDESLEHQTQTHDQESEIVTEGSAVVHSEPSQEGNVPPKVDSEAEVLDEKVSKQIIKEGH Sbjct: 1 MDESLEHQTQTHDQESEIVTEGSAVVHSEPSQEGNVPPKVDSEAEVLDEKVSKQIIKEGH 60 Query: 61 GSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIGVASMKSGE 120 GSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIGVASMKSGE Sbjct: 61 GSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIGVASMKSGE 120 Query: 121 RALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETKEGKARSDMTVEERIGAAD 180 RALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETKEGKARSDMTVEERIGAAD Sbjct: 121 RALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETKEGKARSDMTVEERIGAAD 180 >1Q1C-A nrPDB Length = 280 Score = 183 bits (463), Expect = 2e-46, Method: Composition-based stats. Identities = 57/206 (27%), Positives = 87/206 (42%), Gaps = 22/206 (10%) Query: 20 TEGSAVVHSEPSQEGNVPPKVDSEAEVLDEKVSKQIIKEGHGSK-PSKYSTCFLHYRAWT 78 TE A P + ++ PK DE V K I +EG G++ P F+HY W Sbjct: 29 TESGAQSAPLPMEGVDISPK-------QDEGVLKVIKREGTGTEMPMIGDRVFVHYTGWL 81 Query: 79 KNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIGVASMKSGERALVHVGWELAYGKEGNF 138 + KF+ + + LGK + + I +A+MK GE + E AYG G Sbjct: 82 LDGT-KFDSSLDRKDKFSFDLGK-GEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAG-- 137 Query: 139 SFPNVPPMADLLYEVEVIGFDETKEGKARSDMTVEERIGAADRRKMDGNSLFKEEK---L 195 S P +PP A L++EVE+ F D+T EE G R + G K + + Sbjct: 138 SPPKIPPNATLVFEVELFEFK-------GEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIV 190 Query: 196 EEAMQQYEMAIAYMGDDFMFQLYGKY 221 E A++ Y + + F++ Sbjct: 191 EVALEGYYKDKLFDQRELRFEIGEGE 216 Score = 95.6 bits (236), Expect = 3e-20, Method: Composition-based stats. Identities = 31/124 (25%), Positives = 61/124 (49%), Gaps = 11/124 (8%) Query: 44 AEVLDEKVSKQIIKEGHG-SKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGK- 101 E D + ++I G G +KP++ + + + ++D +Q+ + +G+ Sbjct: 163 TEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGY-------YKDKLFDQRELRFEIGEG 215 Query: 102 EKKELA-GLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDE 160 E +L GL + M+ GE ++V++ A+G G F +PP A+L YE+ + F++ Sbjct: 216 ENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKF-QIPPNAELKYELHLKSFEK 274 Query: 161 TKEG 164 KE Sbjct: 275 AKES 278 >4TW8-A nrPDB Length = 235 Score = 182 bits (462), Expect = 2e-46, Method: Composition-based stats. Identities = 51/178 (28%), Positives = 78/178 (43%), Gaps = 15/178 (8%) Query: 48 DEKVSKQIIKEGHGSK-PSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKEL 106 DE V K I +EG G++ P F+HY W + KF+ + + LGK + + Sbjct: 10 DEGVLKVIKREGTGTEMPMIGDRVFVHYTGWLLDGT-KFDSSLDRKDKFSFDLGK-GEVI 67 Query: 107 AGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETKEGKA 166 I +A+MK GE + E AYG G S P +PP A L++EVE+ F Sbjct: 68 KAWDIAIATMKVGEVCHITCKPEYAYGSAG--SPPKIPPNATLVFEVELFEFK------- 118 Query: 167 RSDMTVEERIGAADRRKMDGNSLFKEEK---LEEAMQQYEMAIAYMGDDFMFQLYGKY 221 D+T EE G R + G K + +E A++ Y + + F++ Sbjct: 119 GEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKDKLFDQRELRFEIGEGE 176 Score = 92.1 bits (227), Expect = 3e-19, Method: Composition-based stats. Identities = 29/121 (23%), Positives = 59/121 (48%), Gaps = 11/121 (9%) Query: 44 AEVLDEKVSKQIIKEGHG-SKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGK- 101 E D + ++I G G +KP++ + + + ++D +Q+ + +G+ Sbjct: 123 TEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGY-------YKDKLFDQRELRFEIGEG 175 Query: 102 EKKELA-GLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDE 160 E +L GL + M+ GE ++V++ A+G G F +PP A+L YE+ + F++ Sbjct: 176 ENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKF-QIPPNAELKYELHLKSFEK 234 Query: 161 T 161 Sbjct: 235 A 235 >4I2W-A nrPDB Length = 961 Score = 168 bits (426), Expect = 3e-42, Method: Composition-based stats. Identities = 46/181 (25%), Positives = 83/181 (45%), Gaps = 20/181 (11%) Query: 175 RIGAADRRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHL 234 R+ A+ + +GN+ K++ +A + Y A+ D+ A++ + Sbjct: 4 RVQTAEEIRDEGNAAVKDQDYIKADELYTEALQLTTDEDK------------ALRPVLYR 51 Query: 235 NIAACLIKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYA 294 N A +K ++ A C L + + KALFRR A+ +LG + A D ++A + + Sbjct: 52 NRAMARLKRDDFEGAQSDCTKALEFDGADVKALFRRSLAREQLGNVGPAFQDAKEALRLS 111 Query: 295 PDDKAIRRELRALA-------EQEKALYQKQKEMYKGIFKGK-DEGGAKSKSLFWLIVLW 346 P+DK I L+ L +Q +L K +M K F+G+ + K +L L+VL Sbjct: 112 PNDKGIVEVLQRLVKANNDKIKQTTSLANKVTDMEKLAFRGEAKDTEQKMTALNNLLVLC 171 Query: 347 Q 347 + Sbjct: 172 R 172 >1IHG-A nrPDB Length = 370 Score = 164 bits (414), Expect = 7e-41, Method: Composition-based stats. Identities = 51/152 (33%), Positives = 80/152 (52%), Gaps = 7/152 (4%) Query: 178 AADRRKMDGNSLFKEEKLEEAMQQYEMAIAYM-GDDFMFQLYG--KYQDMALAVKNPCHL 234 ++ K GN+ FK + E A+++Y + Y+ G + K Q +AL+ C L Sbjct: 222 ISEDLKNIGNTFFKSQNWEMAIKKYTKVLRYVEGSRAAAEDADGAKLQPVALS----CVL 277 Query: 235 NIAACLIKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYA 294 NI AC +K+ + A+ C L + N KAL+RR + L + D A D +KAQ+ A Sbjct: 278 NIGACKLKMSDWQGAVDSCLEALEIDPSNTKALYRRAQGWQGLKEYDQALADLKKAQEIA 337 Query: 295 PDDKAIRRELRALAEQEKALYQKQKEMYKGIF 326 P+DKAI+ EL + ++ KA K+K Y +F Sbjct: 338 PEDKAIQAELLKVKQKIKAQKDKEKAAYAKMF 369 >3O5D-A nrPDB Length = 264 Score = 162 bits (409), Expect = 2e-40, Method: Composition-based stats. Identities = 46/177 (25%), Positives = 73/177 (41%), Gaps = 14/177 (7%) Query: 19 VTEGSAVVHSEPSQEGNVPPKVDSEAEVLDEKVSKQIIKEGHGSK-PSKYSTCFLHYRAW 77 +T ++E S V + + D V K + + G+G + P ++HY+ Sbjct: 5 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 64 Query: 78 TKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIGVASMKSGERALVHVGWELAYGKEGN 137 N + KF+ + +P LGK + + IGVA+MK GE + E AYG G Sbjct: 65 LSNGK-KFDSSHDRNEPFVFSLGK-GQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAG- 121 Query: 138 FSFPNVPPMADLLYEVEVIGFDETKEGKARSDMTVEERIGAADRRKMDGNSLFKEEK 194 S P +P A L +E+E++ F D+ E G R K G + Sbjct: 122 -SLPKIPSNATLFFEIELLDFK-------GEDLF--EDGGIIRRTKRKGEGYSNPNE 168 Score = 95.6 bits (236), Expect = 3e-20, Method: Composition-based stats. Identities = 26/125 (20%), Positives = 56/125 (44%), Gaps = 10/125 (8%) Query: 48 DEKVSKQIIKEGHG-SKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKEL 106 D + ++ ++G G S P++ +T +H F+ + G++ Sbjct: 149 DGGIIRRTKRKGEGYSNPNEGATVEIHLEGRC--GGRMFDC---RDVAFTVGEGEDHDIP 203 Query: 107 AGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETKEGKA 166 G+ + M+ E+ ++++G +G+ G F + P A+L+YEV + F++ KE Sbjct: 204 IGIDKALEKMQREEQCILYLGPRYGFGEAGKPKF-GIEPNAELIYEVTLKSFEKAKES-- 260 Query: 167 RSDMT 171 +M Sbjct: 261 -WEMD 264 >1ROT-A nrPDB Length = 149 Score = 161 bits (406), Expect = 6e-40, Method: Composition-based stats. Identities = 43/130 (33%), Positives = 61/130 (46%), Gaps = 12/130 (9%) Query: 48 DEKVSKQIIKEGHGSK-PSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKEL 106 DE V K I +EG G++ P F+HY W + KF+ + + LGK + + Sbjct: 29 DEGVLKVIKREGTGTETPMIGDRVFVHYTGWLLDGT-KFDSSLDRKDKFSFDLGK-GEVI 86 Query: 107 AGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETKEGKA 166 I VA+MK GE + E AYG G S P +PP A L++EVE+ F Sbjct: 87 KAWDIAVATMKVGELCRITCKPEYAYGSAG--SPPKIPPNATLVFEVELFEFK------- 137 Query: 167 RSDMTVEERI 176 D+T +E Sbjct: 138 GEDLTDDEDG 147 >4DRJ-A nrPDB Length = 144 Score = 160 bits (404), Expect = 9e-40, Method: Composition-based stats. Identities = 45/141 (31%), Positives = 65/141 (46%), Gaps = 12/141 (8%) Query: 20 TEGSAVVHSEPSQEGNVPPKVDSEAEVLDEKVSKQIIKEGHGSK-PSKYSTCFLHYRAWT 78 TE A P + ++ PK DE V K I +EG G++ P F+HY W Sbjct: 13 TESGAQSAPLPMEGVDISPK-------QDEGVLKVIKREGTGTEMPMIGDRVFVHYTGWL 65 Query: 79 KNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIGVASMKSGERALVHVGWELAYGKEGNF 138 + KF+ + + LGK + + I +A+MK GE + E AYG G Sbjct: 66 LDGT-KFDSSLDRKDKFSFDLGK-GEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAG-- 121 Query: 139 SFPNVPPMADLLYEVEVIGFD 159 S P +PP A L++EVE+ F Sbjct: 122 SPPKIPPNATLVFEVELFEFK 142 >2ND5-A nrPDB Length = 111 Score = 158 bits (399), Expect = 3e-39, Method: Composition-based stats. Identities = 33/111 (29%), Positives = 60/111 (54%), Gaps = 5/111 (4%) Query: 50 KVSKQIIKEGHG-SKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAG 108 V + I G G + P + TC +HY ++ + KF+ + +P + +LGK+ + + G Sbjct: 5 GVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGK-KFDSSRDRNKPFKFMLGKQ-EVIRG 62 Query: 109 LAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFD 159 GVA M G+RA + + + AYG G+ +PP A L+++VE++ + Sbjct: 63 WEEGVAQMSVGQRAKLTISPDYAYGATGHPGI--IPPHATLVFDVELLKLE 111 >5I7P-A nrPDB Length = 161 Score = 157 bits (397), Expect = 7e-39, Method: Composition-based stats. Identities = 39/153 (25%), Positives = 68/153 (44%), Gaps = 14/153 (9%) Query: 50 KVSKQIIKEGHG-SKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAG 108 V + I G G + P + T +HY ++ + KF+ + +P + +LGK+ + + G Sbjct: 1 GVQVETISPGDGRTFPKRGQTAVVHYTGMLEDGK-KFDSSRDRNKPFKFMLGKQ-EVIRG 58 Query: 109 LAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIG-----FDETKE 163 GVA M G+RA + + + AYG+ VP D+ V+ + ET + Sbjct: 59 WEEGVAQMSVGQRAKLTISPDYAYGQYDENLVQRVP--KDVFMGVDELQVGMRFLAETDQ 116 Query: 164 GKARSDMTVEERIGAADRRKMDGNSLFKEEKLE 196 G ++T E D +DGN + + L Sbjct: 117 GPVPVEITAVED----DHVVVDGNHMLAGQNLV 145 >4R0X-A nrPDB Length = 122 Score = 157 bits (396), Expect = 9e-39, Method: Composition-based stats. Identities = 36/113 (31%), Positives = 56/113 (49%), Gaps = 5/113 (4%) Query: 48 DEKVSKQIIKEGHGSK-PSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKEL 106 D V K + + G+G + P ++HY+ N + KF+ + +P LGK + + Sbjct: 12 DRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGK-KFDSSHDRNEPFVFSLGK-GQVI 69 Query: 107 AGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFD 159 IGVA+MK GE + E AYG G S P +P A L +E+E++ F Sbjct: 70 KAWDIGVATMKKGEICHLLCKPEYAYGSAG--SLPGIPSNATLFFEIELLDFK 120 >3O5E-A nrPDB Length = 144 Score = 154 bits (390), Expect = 4e-38, Method: Composition-based stats. Identities = 40/142 (28%), Positives = 65/142 (45%), Gaps = 5/142 (3%) Query: 19 VTEGSAVVHSEPSQEGNVPPKVDSEAEVLDEKVSKQIIKEGHGSK-PSKYSTCFLHYRAW 77 +T ++E S V + + D V K + + G+G + P ++HY+ Sbjct: 5 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 64 Query: 78 TKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIGVASMKSGERALVHVGWELAYGKEGN 137 N + KF+ + +P LGK + + IGVA+MK GE + E AYG G Sbjct: 65 LSNGK-KFDSSHDRNEPFVFSLGK-GQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAG- 121 Query: 138 FSFPNVPPMADLLYEVEVIGFD 159 S P +P A L +E+E++ F Sbjct: 122 -SLPKIPSNATLFFEIELLDFK 142 >5HWB-A nrPDB Length = 115 Score = 153 bits (387), Expect = 9e-38, Method: Composition-based stats. Identities = 29/114 (25%), Positives = 55/114 (48%), Gaps = 5/114 (4%) Query: 50 KVSKQIIKEGHG-SKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAG 108 V+K++ G+G P K +HY + KF+ + +P + +G + + G Sbjct: 5 GVTKELKSPGNGVDFPKKGDFVTIHYTGRLTDGS-KFDSSVDRNEPFQTQIGT-GRVIKG 62 Query: 109 LAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETK 162 GV M GE+A++ + + YG G P +P + L++EVE++G + + Sbjct: 63 WDEGVPQMSLGEKAVLTITPDYGYGARGF--PPVIPGNSTLIFEVELLGINNKR 114 >5HUA-A nrPDB Length = 115 Score = 151 bits (382), Expect = 4e-37, Method: Composition-based stats. Identities = 28/117 (23%), Positives = 54/117 (46%), Gaps = 5/117 (4%) Query: 44 AEVLDEKVSKQIIKEGHG-SKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKE 102 +E ++ V + G G + P + +HY +N Q KF+ + P + +G Sbjct: 3 SETIEGGVKIDRLSPGDGKTFPKQGDLVTIHYTGTLENGQ-KFDSSVDRGSPFQCNIGV- 60 Query: 103 KKELAGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFD 159 + + G G+ + GE+A + + AYG G +PP A L+++VE++ + Sbjct: 61 GQVIKGWDAGIPKLSVGEKARLTIPGPYAYGPRGFPGL--IPPNATLIFDVELLKVN 115 >1YAT-A nrPDB Length = 113 Score = 150 bits (379), Expect = 8e-37, Method: Composition-based stats. Identities = 29/117 (24%), Positives = 55/117 (47%), Gaps = 5/117 (4%) Query: 44 AEVLDEKVSKQIIKEGHG-SKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKE 102 +EV++ V I G G + P +HY +N Q KF+ + P + +G Sbjct: 1 SEVIEGNVKIDRISPGDGATFPKTGDLVTIHYTGTLENGQ-KFDSSVDRGSPFQCNIGV- 58 Query: 103 KKELAGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFD 159 + + G +G+ + GE+A + + AYG G +PP + L+++VE++ + Sbjct: 59 GQVIKGWDVGIPKLSVGEKARLTIPGPYAYGPRGFPGL--IPPNSTLVFDVELLKVN 113 >5T9S-F nrPDB Length = 108 Score = 150 bits (378), Expect = 1e-36, Method: Composition-based stats. Identities = 33/111 (29%), Positives = 58/111 (52%), Gaps = 5/111 (4%) Query: 50 KVSKQIIKEGHG-SKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAG 108 V + I G G + P K TC +HY +N + KF+ + +P + +GK+ + + G Sbjct: 2 GVEIETISPGDGRTFPKKGQTCVVHYTGMLQNGK-KFDSSRDRNKPFKFRIGKQ-EVIKG 59 Query: 109 LAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFD 159 G A M G+RA + ++AYG G+ +PP A L+++VE++ + Sbjct: 60 FEEGAAQMSLGQRAKLTCTPDVAYGATGHPGV--IPPNATLIFDVELLNLE 108 >1R9H-A nrPDB Length = 135 Score = 149 bits (377), Expect = 1e-36, Method: Composition-based stats. Identities = 38/121 (31%), Positives = 55/121 (45%), Gaps = 5/121 (4%) Query: 48 DEKVSKQIIKEGHGS-KPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKEL 106 D V K I KEG G KP+ +T +HY +N KF+ + LG+ + Sbjct: 13 DGGVLKLIKKEGQGVVKPTTGTTVKVHYVGTLENGT-KFDSSRDRGDQFSFNLGR-GNVI 70 Query: 107 AGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETKEGKA 166 G +GVA+M GE A + + YG G S P +P A L++EVE+ + Sbjct: 71 KGWDLGVATMTKGEVAEFTIRSDYGYGDAG--SPPKIPGGATLIFEVELFEWSAEDISPD 128 Query: 167 R 167 R Sbjct: 129 R 129 >5JHE-A nrPDB Length = 397 Score = 149 bits (376), Expect = 2e-36, Method: Composition-based stats. Identities = 36/156 (23%), Positives = 74/156 (47%), Gaps = 5/156 (3%) Query: 176 IGAADRRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMA-LAVKNPCHL 234 + AA+ K G LFK++ A +Y ++ Y+ + K +++ + +K +L Sbjct: 241 LEAANIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFINLKMKIYL 300 Query: 235 NIAACLIKLKRYDEAIGHCNIVLTEE----EKNPKALFRRGKAKAELGQMDSARDDFRKA 290 N++ L L+RYD+AI + +L + KA +RRG + + ++D A D+ Sbjct: 301 NLSLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYIFC 360 Query: 291 QKYAPDDKAIRRELRALAEQEKALYQKQKEMYKGIF 326 ++ PDD+ I + + + + +K ++ F Sbjct: 361 KEKNPDDEVIEQRIEYVNRLIEENKEKTRKNISKFF 396 >2Y78-A nrPDB Length = 133 Score = 148 bits (374), Expect = 3e-36, Method: Composition-based stats. Identities = 34/124 (27%), Positives = 53/124 (42%), Gaps = 4/124 (3%) Query: 34 GNVPPKVDSEAEVLDEKVSKQIIKEGHGSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQ 93 G VP + + + + EG G++ T +HY W + Q KF+ + Sbjct: 13 GLVPRGSHMTVVTTESGLKYEDLTEGSGAEARAGQTVSVHYTGWLTDGQ-KFDSSKDRND 71 Query: 94 PIELVLGKEKKELAGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEV 153 P VLG + G GV MK G + + +L YG G +PP A L++EV Sbjct: 72 PFAFVLGG-GMVIKGWDEGVQGMKVGGVRRLTIPPQLGYGARGAGGV--IPPNATLVFEV 128 Query: 154 EVIG 157 E++ Sbjct: 129 ELLD 132 >2L2S-A nrPDB Length = 117 Score = 148 bits (373), Expect = 4e-36, Method: Composition-based stats. Identities = 31/112 (27%), Positives = 50/112 (44%), Gaps = 4/112 (3%) Query: 46 VLDEKVSKQIIKEGHGSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKE 105 + + + + EG G++ T +HY W + Q KF+ + P VLG Sbjct: 9 TTESGLKYEDLTEGSGAEARAGQTVSVHYTGWLTDGQ-KFDSSKDRNDPFAFVLGG-GMV 66 Query: 106 LAGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIG 157 + G GV MK G + + +L YG G +PP A L++EVE++ Sbjct: 67 IKGWDEGVQGMKVGGVRRLTIPPQLGYGARGAGGV--IPPNATLVFEVELLD 116 >5L1D-B nrPDB Length = 158 Score = 147 bits (371), Expect = 6e-36, Method: Composition-based stats. Identities = 36/123 (29%), Positives = 63/123 (51%), Gaps = 8/123 (6%) Query: 38 PKVDSEAEVLDEKVSKQIIKEGHG-SKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIE 96 P+ E E+ V + I G G + P K TC +HY +N + KF+ + +P + Sbjct: 43 PQGQREPEL---GVEIETISPGDGRTFPKKGQTCVVHYTGMLQNGK-KFDSSRDRNKPFK 98 Query: 97 LVLGKEKKELAGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVI 156 +GK+ + + G G A M G+RA + ++AYG G+ +PP A L+++VE++ Sbjct: 99 FRIGKQ-EVIKGFEEGAAQMSLGQRAKLTCTPDVAYGATGHPGV--IPPNATLIFDVELL 155 Query: 157 GFD 159 + Sbjct: 156 NLE 158 >3IHZ-A nrPDB Length = 126 Score = 143 bits (361), Expect = 1e-34, Method: Composition-based stats. Identities = 34/116 (29%), Positives = 59/116 (50%), Gaps = 6/116 (5%) Query: 48 DEKVSKQIIKEGHGSK---PSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKK 104 D V K I+++G G + P K + +HY ++S F+ + P + LG + + Sbjct: 14 DGGVVKTILRKGEGGEENAPKKGNEVTVHYVGKLESSGKVFDSSRERNVPFKFHLG-QGE 72 Query: 105 ELAGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDE 160 + G I VASM E+ V + + YG+EG ++P + L++E+E+I F E Sbjct: 73 VIKGWDICVASMTKNEKCSVRLDSKYGYGEEG--CGESIPGNSVLIFEIELISFRE 126 >4GIV-A nrPDB Length = 209 Score = 142 bits (359), Expect = 1e-34, Method: Composition-based stats. Identities = 31/112 (27%), Positives = 49/112 (43%), Gaps = 4/112 (3%) Query: 46 VLDEKVSKQIIKEGHGSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKE 105 + + + + EG G++ T +HY W + Q KF + P VLG Sbjct: 101 TTESGLKYEDLTEGSGAEARAGQTVSVHYTGWLTDGQ-KFGSSKDRNDPFAFVLGG-GMV 158 Query: 106 LAGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIG 157 + G GV MK G + + +L YG G +PP A L++EVE++ Sbjct: 159 IKGWDEGVQGMKVGGVRRLTIPPQLGYGARGAGGV--IPPNATLVFEVELLD 208 >4QT3-A nrPDB Length = 134 Score = 142 bits (357), Expect = 3e-34, Method: Composition-based stats. Identities = 34/121 (28%), Positives = 61/121 (50%), Gaps = 6/121 (4%) Query: 46 VLDEKVSKQIIK---EGHGSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKE 102 D V K I+K EG + P K + +HY +++ F+ ++ P + L ++ Sbjct: 9 TADGGVIKTILKKGDEGEENIPKKGNEVTVHYVGKLESTGKVFDSSFDRNVPFKFHL-EQ 67 Query: 103 KKELAGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETK 162 + + G I V+SM+ E+ LV + YG EG ++P + LL+E+E++ F E + Sbjct: 68 GEVIKGWDICVSSMRKNEKCLVRIESMYGYGDEG--CGESIPGNSVLLFEIELLSFRELE 125 Query: 163 E 163 E Sbjct: 126 E 126 >2LGO-A nrPDB Length = 130 Score = 141 bits (355), Expect = 4e-34, Method: Composition-based stats. Identities = 33/111 (29%), Positives = 60/111 (54%), Gaps = 5/111 (4%) Query: 47 LDEKVSKQIIKEGHG-SKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKE 105 + ++ K+++ G G +KP +HY + + F+ + +P + LG + Sbjct: 22 MSAQLEKKVLTPGDGVTKPQAGKKVTVHYDGRFPDGKQ-FDSSRSRGKPFQFTLG-AGEV 79 Query: 106 LAGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVI 156 + G GVA+M GE+AL + ++LAYG+ G P +PP A L++EVE++ Sbjct: 80 IKGWDQGVATMTLGEKALFTIPYQLAYGERGY--PPVIPPKATLVFEVELL 128 >6B4P-A nrPDB Length = 127 Score = 140 bits (353), Expect = 8e-34, Method: Composition-based stats. Identities = 33/114 (28%), Positives = 59/114 (51%), Gaps = 7/114 (6%) Query: 48 DEKVSKQIIKEGHGSK-PSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKEL 106 D+++ K+II G + P S +HY + + KF+ + QP LGK + + Sbjct: 19 DQRLKKKIITAGSSDEQPPIGSKVSVHYTGTLTSGK-KFDSSLDRGQPFVFTLGK-GEVI 76 Query: 107 AGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPN-VPPMADLLYEVEVIGFD 159 G +GV SMK GE++ + + AYG N + P +P + L++E+E++ + Sbjct: 77 RGWDLGVKSMKKGEKSYFEIPSDYAYG---NNAIPGLIPANSTLMFEIELLSWK 127 >3UQI-A nrPDB Length = 108 Score = 137 bits (344), Expect = 9e-33, Method: Composition-based stats. Identities = 26/111 (23%), Positives = 48/111 (43%), Gaps = 5/111 (4%) Query: 50 KVSKQIIKEGHGSK-PSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAG 108 V + G + P +HY + + F+ + +P +G+ + + G Sbjct: 2 GVQVVTLAAGDEATYPKAGQVAVVHYTGTLADGKV-FDSSRTRGKPFRFTVGR-GEVIRG 59 Query: 109 LAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFD 159 GVA M G+RA + + AYG G+ +PP A L ++VE++ + Sbjct: 60 WDEGVAQMSVGQRAKLVCSPDYAYGSRGHPGV--IPPNATLTFDVELLRVE 108 >3B7X-A nrPDB Length = 134 Score = 134 bits (337), Expect = 6e-32, Method: Composition-based stats. Identities = 32/111 (28%), Positives = 55/111 (49%), Gaps = 3/111 (2%) Query: 48 DEKVSKQIIKEGHGSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELA 107 D V K +I+EG G + ++ + Y + ++ F+ + + P + LG E L Sbjct: 25 DRGVLKDVIREGAGDLVAPDASVLVKYSGYLEHMDRPFDSNYFRKTPRLMKLG-EDITLW 83 Query: 108 GLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGF 158 G+ +G+ SM+ GE A AYG G P +PP +L+E+E++ F Sbjct: 84 GMELGLLSMRRGELARFLFKPNYAYGTLG--CPPLIPPNTTVLFEIELLDF 132 >3JXV-A nrPDB Length = 356 Score = 131 bits (329), Expect = 5e-31, Method: Composition-based stats. Identities = 33/142 (23%), Positives = 62/142 (43%), Gaps = 12/142 (8%) Query: 62 SKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIGVASMKSGER 121 P +HY + + KF+ + + LG + + + G G+ +MK GE Sbjct: 25 DTPEVGDEVEVHYTGTLLDGK-KFDSSRDRDDTFKFKLG-QGQVIKGWDQGIKTMKKGEN 82 Query: 122 ALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETKEGKARSDMTVEERIGAADR 181 AL + ELAYG+ G S P +P A L ++VE++ + ++ + + G + Sbjct: 83 ALFTIPPELAYGESG--SPPTIPANATLQFDVELLSWTSVRD--------IAKDGGIFKK 132 Query: 182 RKMDGNSLFKEEKLEEAMQQYE 203 +G+ + +E +YE Sbjct: 133 ILKEGDKWENPKDPDEVFVKYE 154 Score = 130 bits (327), Expect = 9e-31, Method: Composition-based stats. Identities = 34/114 (29%), Positives = 59/114 (51%), Gaps = 2/114 (1%) Query: 48 DEKVSKQIIKEGHG-SKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKEL 106 D+K+ K+++KE G +P++ + + ++ + EQ+P E E+ + Sbjct: 243 DKKILKKVLKEXEGYERPNEGAVVTVKITGKLQDGTVFLKKGHDEQEPFEFKT-DEEAVI 301 Query: 107 AGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDE 160 GL V +MK GE ALV + E AYG + VPP + ++YEVE++ F + Sbjct: 302 EGLDRAVLNMKKGEVALVTIPPEYAYGSTESKQDAIVPPNSTVIYEVELVSFVK 355 Score = 87.1 bits (214), Expect = 1e-17, Method: Composition-based stats. Identities = 37/175 (21%), Positives = 66/175 (37%), Gaps = 25/175 (14%) Query: 48 DEKVSKQIIKEGHG-SKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKEL 106 D + K+I+KEG P F+ Y A ++ + E + K+ Sbjct: 126 DGGIFKKILKEGDKWENPKDPDEVFVKYEARLEDGTVV---SKSEGVEFTV---KDGHLC 179 Query: 107 AGLAIGVASMKSGERALVHVGWELAYGKEGNFS---FPNVPPMADLLYEVEVIGFDETKE 163 LA V +MK GE+ L+ V + +G+ G + VPP A L+ ++E++ + E Sbjct: 180 PALAKAVKTMKKGEKVLLAVKPQYGFGEMGRPAAGEGGAVPPNASLVIDLELVSWKTVTE 239 Query: 164 --------GKARSDMTVEERIGAADRRKM-------DGNSLFKEEKLEEAMQQYE 203 K + ER + DG K+ E+ +++ Sbjct: 240 IGDDKKILKKVLKEXEGYERPNEGAVVTVKITGKLQDGTVFLKKGHDEQEPFEFK 294 >5B8I-C nrPDB Length = 130 Score = 129 bits (323), Expect = 2e-30, Method: Composition-based stats. Identities = 34/122 (27%), Positives = 58/122 (47%), Gaps = 13/122 (10%) Query: 50 KVSKQIIKEGHG-SKPSKYSTCFLHYRAWTKNS--------QHKFEDTWHEQQPIELVLG 100 V+K+I+KEG+G KP K ++YR +S KF+ T + + +G Sbjct: 12 GVTKKILKEGNGVDKPVKGDDIVMNYRGCLYDSSKPSEHFMGRKFDSTEERGE-FKTKIG 70 Query: 101 KEKKELAGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDE 160 + G V M GE++++ + + AYG G +PP A L++EVE+ G + Sbjct: 71 I-GVVIRGWDEAVLQMSLGEKSILTITDDYAYGARGFPGL--IPPHATLVFEVELKGINS 127 Query: 161 TK 162 + Sbjct: 128 KR 129 >5I7Q-A nrPDB Length = 162 Score = 125 bits (314), Expect = 3e-29, Method: Composition-based stats. Identities = 25/85 (29%), Positives = 44/85 (51%), Gaps = 3/85 (3%) Query: 50 KVSKQIIKEGHG-SKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAG 108 V + I G G + P + T +HY ++ + KF+ + +P + +LGK+ + + G Sbjct: 1 GVQVETISPGDGRTFPKRGQTAVVHYTGMLEDGK-KFDSSRDRNKPFKFMLGKQ-EVIRG 58 Query: 109 LAIGVASMKSGERALVHVGWELAYG 133 GVA M G+RA + + + AYG Sbjct: 59 WEEGVAQMSVGQRAKLTISPDYAYG 83 >6FO1-G nrPDB Length = 665 Score = 123 bits (309), Expect = 1e-28, Method: Composition-based stats. Identities = 37/145 (25%), Positives = 60/145 (41%), Gaps = 17/145 (11%) Query: 166 ARSDMTVEERIGAADRRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMA 225 R + ++ A K GN FKE K E A++ Y IA G + + Sbjct: 269 ERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPA-------- 320 Query: 226 LAVKNPCHLNIAACLIKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARD 285 N A +K+++Y+EA C + + KA RRG A+ LG+++ A+ Sbjct: 321 ---------NRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQ 371 Query: 286 DFRKAQKYAPDDKAIRRELRALAEQ 310 DF P +K EL + ++ Sbjct: 372 DFETVLLLEPGNKQAVTELSKIKKE 396 Score = 94.8 bits (234), Expect = 5e-20, Method: Composition-based stats. Identities = 33/160 (20%), Positives = 65/160 (40%), Gaps = 20/160 (12%) Query: 175 RIGAADRRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHL 234 A K GN FK+ K +EA+ Y + + + Sbjct: 129 DSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPT----------------- 171 Query: 235 NIAACLIKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYA 294 N A+ +LK++ A CN+ + KA RRG A+ L +++ A+ D+ + + Sbjct: 172 NRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELE 231 Query: 295 PDDKAIRRELRALAEQEKAL---YQKQKEMYKGIFKGKDE 331 P++ ELR +++ + Y K+ ++ +G+ + Sbjct: 232 PNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERK 271 >4NNR-A nrPDB Length = 142 Score = 116 bits (291), Expect = 1e-26, Method: Composition-based stats. Identities = 27/101 (26%), Positives = 47/101 (46%), Gaps = 4/101 (3%) Query: 63 KPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIGVASMKSGERA 122 K K +HY ++ F+ + + QP LG + + G G+ M GE+ Sbjct: 45 KSRKGDVLHMHYTGKLEDGTE-FDSSLPQNQPFVFSLGT-GQVIKGWDQGLLGMCEGEKR 102 Query: 123 LVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETKE 163 + + EL YG+ G + P +P A L++EVE++ + E Sbjct: 103 KLVIPSELGYGERG--APPKIPGGATLVFEVELLKIERRTE 141 >2PBC-A nrPDB Length = 102 Score = 116 bits (289), Expect = 2e-26, Method: Composition-based stats. Identities = 28/105 (26%), Positives = 48/105 (45%), Gaps = 4/105 (3%) Query: 59 GHGSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIGVASMKS 118 G K K +HY ++ F+ + + QP LG + + G G+ M Sbjct: 1 GSPIKSRKGDVLHMHYTGKLEDGTE-FDSSLPQNQPFVFSLGT-GQVIKGWDQGLLGMCE 58 Query: 119 GERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETKE 163 GE+ + + EL YG+ G + P +P A L++EVE++ + E Sbjct: 59 GEKRKLVIPSELGYGERG--APPKIPGGATLVFEVELLKIERRTE 101 >5HW8-A nrPDB Length = 122 Score = 112 bits (281), Expect = 2e-25, Method: Composition-based stats. Identities = 25/120 (20%), Positives = 49/120 (40%), Gaps = 16/120 (13%) Query: 52 SKQIIKEGHGSK-PSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGLA 110 +I++EG + T +HY N + F+ + +P +G + + G Sbjct: 5 QIEIVQEGDNTTFAKPGDTVTIHYDGKLTNGKE-FDSSRKRGKPFTCTVGV-GQVIKGWD 62 Query: 111 IGV-----------ASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFD 159 I + + G +A++ + LAYG G + P L++EVE++G + Sbjct: 63 ISLTNNYGKGGANLPKISKGTKAILTIPPNLAYGPRGIPGI--IGPNETLVFEVELLGVN 120 >4BF8-A nrPDB Length = 117 Score = 105 bits (262), Expect = 3e-23, Method: Composition-based stats. Identities = 26/117 (22%), Positives = 53/117 (45%), Gaps = 6/117 (5%) Query: 43 EAEVLDEKVSKQIIKEGHGSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKE 102 + ++L+ + + G G K + + Y KN + F+ + +P LG + Sbjct: 7 KTKLLEGGIIIEDRVTGKGPHAKKGTRVGMRYVGKLKNGKV-FDKNT-KGKPFVFKLG-Q 63 Query: 103 KKELAGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFD 159 + + G IGVA M G + + AYGK+ + P +P ++L ++V+++ Sbjct: 64 GEVIKGWDIGVAGMAVGGERRIVIPAPYAYGKQ---ALPGIPANSELTFDVKLVSMK 117 >1Q6H-A nrPDB Length = 224 Score = 102 bits (254), Expect = 3e-22, Method: Composition-based stats. Identities = 26/110 (23%), Positives = 55/110 (50%), Gaps = 7/110 (6%) Query: 50 KVSKQIIKEGHGSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGL 109 + Q+++ G G P T ++Y+ + + F++++ +P+ L + G Sbjct: 122 GLVYQVVEAGKGEAPKDSDTVVVNYKGTLIDGKE-FDNSYTRGEPLSFRL---DGVIPGW 177 Query: 110 AIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFD 159 G+ ++K G + + + ELAYGK G P +PP + L+++VE++ Sbjct: 178 TEGLKNIKKGGKIKLVIPPELAYGKAG---VPGIPPNSTLVFDVELLDVK 224 >2MPH-A nrPDB Length = 224 Score = 101 bits (252), Expect = 4e-22, Method: Composition-based stats. Identities = 35/133 (26%), Positives = 57/133 (42%), Gaps = 14/133 (10%) Query: 38 PKVDSEAEVLDEK---VSKQIIKEGHGS-KPSKYSTCFLHYRAWTKNSQHKFEDT----- 88 PK E LDE +K ++K+G + P K Y ++ F+ Sbjct: 95 PKETKSEETLDEGPPKYTKSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTV-FDTNIQTSA 153 Query: 89 --WHEQQPIELVLGKEKKELAGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPM 146 +P+ +G K + G + +M GE+A + + E AYGK+G +PP Sbjct: 154 KKKKNAKPLSFKVGV-GKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQP-DAKIPPN 211 Query: 147 ADLLYEVEVIGFD 159 A L +EVE++ D Sbjct: 212 AKLTFEVELVDID 224 >1Y0O-A nrPDB Length = 129 Score = 101 bits (251), Expect = 5e-22, Method: Composition-based stats. Identities = 26/108 (24%), Positives = 49/108 (45%), Gaps = 11/108 (10%) Query: 59 GHGSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIGV----- 113 G+G + K HY +N + F+ +++ +P+ +G + + G G+ Sbjct: 22 GYGPEAVKGQLIKAHYVGKLENGKV-FDSSYNRGKPLTFRIGV-GEVIKGWDQGILGSDG 79 Query: 114 -ASMKSGERALVHVGWELAYGKEGNFSFPN---VPPMADLLYEVEVIG 157 M +G + + + ELAYG G +PP + LL+++E IG Sbjct: 80 IPPMLTGGKRTLRIPPELAYGDRGAGCKGGSCLIPPASVLLFDIEYIG 127 >1JVW-A nrPDB Length = 167 Score = 100 bits (250), Expect = 8e-22, Method: Composition-based stats. Identities = 31/140 (22%), Positives = 61/140 (43%), Gaps = 7/140 (5%) Query: 43 EAEVLDEKVSKQIIKEGHGSK-PSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGK 101 +A L + Q I G G + P+ C +HY ++ F+ + +P + Sbjct: 31 DAVKLPSGLVFQRIARGSGKRAPAIDDKCEVHYTGRLRDGTV-FDSSRERGKPTTF---R 86 Query: 102 EKKELAGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDET 161 + + G + M+ G+R + + ++LAYG G +PP + L ++VE+I + Sbjct: 87 PNEVIKGWTEALQLMREGDRWRLFIPYDLAYGVTGGGGM--IPPYSPLEFDVELISIKDG 144 Query: 162 KEGKARSDMTVEERIGAADR 181 +G+ ++ R DR Sbjct: 145 GKGRTAEEVDEILRKAEEDR 164 >3EY6-A nrPDB Length = 121 Score = 99.8 bits (247), Expect = 2e-21, Method: Composition-based stats. Identities = 28/120 (23%), Positives = 46/120 (38%), Gaps = 13/120 (10%) Query: 51 VSKQIIKEG--HGSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAG 108 + K+ + G S+P K +H + +N E+ + LG + + Sbjct: 13 LRKKTLVPGPPGSSRPVKGQVVTVHLQTSLENGTR-----VQEEPELVFTLG-DCDVIQA 66 Query: 109 LAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETKEGKARS 168 L + V M GE A+V + YG +G P +PP A L EV + +G Sbjct: 67 LDLSVPLMDVGETAMVTADSKYCYGPQGRS--PYIPPHAALCLEVTL---KTAVDGPDLE 121 >5D75-A nrPDB Length = 124 Score = 98.7 bits (244), Expect = 3e-21, Method: Composition-based stats. Identities = 30/118 (25%), Positives = 52/118 (44%), Gaps = 11/118 (9%) Query: 50 KVSKQIIKEGHGS-KPSKYSTCFLHYRAWTKNSQHKFEDT-------WHEQQPIELVLGK 101 K +K ++K+G + P K Y ++ F+ +P+ +G Sbjct: 2 KYTKSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTV-FDTNIQTSAKKKKNAKPLSFKVGV 60 Query: 102 EKKELAGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFD 159 K + G + +M GE+A + + E AYGK+G +PP A L +EVE++ D Sbjct: 61 -GKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQP-DAKIPPNAKLTFEVELVDID 116 >2D9F-A nrPDB Length = 135 Score = 98.7 bits (244), Expect = 4e-21, Method: Composition-based stats. Identities = 28/121 (23%), Positives = 47/121 (38%), Gaps = 12/121 (9%) Query: 51 VSKQIIKEG--HGSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAG 108 + K+ + G S+P K +H + +N E+ + LG + + Sbjct: 19 LRKKTLVPGPPGSSRPVKGQVVTVHLQTSLENGTR-----VQEEPELVFTLG-DCDVIQA 72 Query: 109 LAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETKEGKARS 168 L + V M GE A+V + YG +G+ S P +PP A L EV + + Sbjct: 73 LDLSVPLMDVGETAMVTADSKYCYGPQGSRS-PYIPPHAALCLEVTL---KTAVDRPDLE 128 Query: 169 D 169 Sbjct: 129 M 129 >5JJT-A nrPDB Length = 479 Score = 97.1 bits (240), Expect = 1e-20, Method: Composition-based stats. Identities = 31/149 (20%), Positives = 57/149 (38%), Gaps = 17/149 (11%) Query: 171 TVEERIGAADRRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKN 230 + A+ K N FK K A+ Y AI ++ ++ Sbjct: 1 NENSDVSRAEEFKSQANEAFKGHKYSSAIDLYTKAIELNSNNAVY--------------- 45 Query: 231 PCHLNIAACLIKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKA 290 N A KL+ Y AI + + + + K +RRG A +G+ A DF++ Sbjct: 46 --WANRAFAHTKLEEYGSAIQDASKAIEVDSRYSKGYYRRGAAYLAMGKFKDALKDFQQV 103 Query: 291 QKYAPDDKAIRRELRALAEQEKALYQKQK 319 ++ +P+D R+L+ + L ++ Sbjct: 104 KRLSPNDPDATRKLKECEKAVMKLKFEEA 132 >2MF9-A nrPDB Length = 157 Score = 96.4 bits (238), Expect = 2e-20, Method: Composition-based stats. Identities = 28/108 (25%), Positives = 46/108 (42%), Gaps = 9/108 (8%) Query: 51 VSKQIIKEG--HGSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAG 108 + K+ + G S+P K +H + +N E+ + LG + + Sbjct: 45 LRKKTLVPGPPGSSRPVKGQVVTVHLQTSLENGTR-----VQEEPELVFTLG-DCDVIQA 98 Query: 109 LAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVI 156 L + V M GE A+V + YG +G+ S P +PP A L EV + Sbjct: 99 LDLSVPLMDVGETAMVTADSKYCYGPQGSRS-PYIPPHAALCLEVTLK 145 >2VCD-A nrPDB Length = 137 Score = 92.9 bits (229), Expect = 2e-19, Method: Composition-based stats. Identities = 24/116 (20%), Positives = 47/116 (40%), Gaps = 6/116 (5%) Query: 46 VLDEKVSKQIIKEGHGSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKE 105 VL + ++I G+G KP K T + Y + F+ T +P + + Sbjct: 27 VLPSGLQYKVINSGNGVKPGKSDTVTVEYTGRLIDGTV-FDSTEKTGKPATFQV---SQV 82 Query: 106 LAGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDET 161 + G + M +G ++V LAYG + P L++++ +I ++ Sbjct: 83 IPGWTEALQLMPAGSTWEIYVPSGLAYGPRSVGGP--IGPNETLIFKIHLISVKKS 136 >1FD9-A nrPDB Length = 213 Score = 91.0 bits (224), Expect = 8e-19, Method: Composition-based stats. Identities = 24/116 (20%), Positives = 47/116 (40%), Gaps = 6/116 (5%) Query: 46 VLDEKVSKQIIKEGHGSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKE 105 VL + ++I G+G KP K T + Y + F+ T +P + + Sbjct: 103 VLPSGLQYKVINSGNGVKPGKSDTVTVEYTGRLIDGTV-FDSTEKTGKPATFQV---SQV 158 Query: 106 LAGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDET 161 + G + M +G ++V LAYG + P L++++ +I ++ Sbjct: 159 IPGWTEALQLMPAGSTWEIYVPSGLAYGPRSVGGP--IGPNETLIFKIHLISVKKS 212 >4DIP-A nrPDB Length = 125 Score = 90.6 bits (223), Expect = 9e-19, Method: Composition-based stats. Identities = 30/129 (23%), Positives = 52/129 (40%), Gaps = 13/129 (10%) Query: 34 GNVPPKVDSEAEVLDEKVSKQIIKEGHGSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQ- 92 G + P+ + + EVL + +G +HY + + F T Sbjct: 6 GALIPEPEVKIEVLQKPFICHRKTKG-------GDLMLVHYEGYLEKDGSLFHSTHKHNN 58 Query: 93 -QPIELVLGKEKKELAGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLY 151 QPI LG + L G G+ M GE+ + + L YGKEG +PP + L++ Sbjct: 59 GQPIWFTLGILEA-LKGWDQGLKGMCVGEKRKLIIPPALGYGKEGKGK---IPPESTLIF 114 Query: 152 EVEVIGFDE 160 ++++ Sbjct: 115 NIDLLEIRN 123 >4MSP-A nrPDB Length = 200 Score = 90.6 bits (223), Expect = 9e-19, Method: Composition-based stats. Identities = 35/189 (18%), Positives = 73/189 (38%), Gaps = 22/189 (11%) Query: 38 PKVDSEAEVLDEKVSKQIIKEGHGSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQ--QPI 95 P+ + + EVL + +G +HY + + F T QPI Sbjct: 12 PEPEVKIEVLQKPFICHRKTKG-------GDLMLVHYEGYLEKDGSLFHSTHKHNNGQPI 64 Query: 96 ELVLGKEKKELAGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEV 155 LG + L G G+ M GE+ + + L YGKEG +PP + L++ +++ Sbjct: 65 WFTLGILEA-LKGWDQGLKGMCVGEKRKLIIPPALGYGKEGKGK---IPPESTLIFNIDL 120 Query: 156 IGFDET-KEGKARSDMTVEERIGAADRRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFM 214 + + ++ +M + + + K + + K+E +++ + D + Sbjct: 121 LEIRNGPRSHESFQEMDLNDDWKLS---KDEVKAYLKKE-----FEKHGAVVNESHHDAL 172 Query: 215 FQLYGKYQD 223 + +D Sbjct: 173 VEDIFDKED 181 >4JA9-A nrPDB Length = 488 Score = 89.1 bits (219), Expect = 3e-18, Method: Composition-based stats. Identities = 28/158 (17%), Positives = 59/158 (37%), Gaps = 18/158 (11%) Query: 164 GKARSDMTVEERIGAADRRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQD 223 R + E + A+ K N FK + E A++ Y AI + ++ Sbjct: 2 SHMRDEPPAEGTLKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIY-------- 53 Query: 224 MALAVKNPCHLNIAACLIKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSA 283 + N + ++ + Y A+G + ++K K +RR + LG+ +A Sbjct: 54 ---------YGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAA 104 Query: 284 RDDFRKAQKYAPDDKAIRRELRALAEQEKALYQKQKEM 321 D+ K P+DK + + + + ++ + Sbjct: 105 LRDYETVVKVKPNDKDAKMKYQEC-SKIVKQKAFERAI 141 >1A17-A nrPDB Length = 166 Score = 79.0 bits (193), Expect = 3e-15, Method: Composition-based stats. Identities = 26/146 (17%), Positives = 55/146 (37%), Gaps = 18/146 (12%) Query: 176 IGAADRRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLN 235 + A+ K N FK + E A++ Y AI + ++ + N Sbjct: 10 LKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIY-----------------YGN 52 Query: 236 IAACLIKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAP 295 + ++ + Y A+G + ++K K +RR + LG+ +A D+ K P Sbjct: 53 RSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKP 112 Query: 296 DDKAIRRELRALAEQEKALYQKQKEM 321 DK + + + + ++ + Sbjct: 113 HDKDAKMKYQEC-NKIVKQKAFERAI 137 >5XB0-A nrPDB Length = 133 Score = 77.1 bits (188), Expect = 1e-14, Method: Composition-based stats. Identities = 23/114 (20%), Positives = 46/114 (40%), Gaps = 9/114 (7%) Query: 47 LDEKVSKQIIKEGHGSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKEL 106 L + + + G G KP + Y + + F+ + QP L + Sbjct: 29 LADGILMTELTPGTGPKPDANGRVEVRYVGRLPDGKI-FDQST---QPQWFRL---DSVI 81 Query: 107 AGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDE 160 +G + +M +G + + + + AYG EG + P L++E+E+I + Sbjct: 82 SGWTSALQNMPTGAKWRLVIPSDQAYGAEGAGDL--IDPFTPLVFEIELIAVSQ 133 >2C2L-A nrPDB Length = 281 Score = 67.5 bits (163), Expect = 8e-12, Method: Composition-based stats. Identities = 28/120 (23%), Positives = 48/120 (40%), Gaps = 17/120 (14%) Query: 179 ADRRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAA 238 A K GN LF K EA Y AI + + N A Sbjct: 4 AQELKEQGNRLFVGRKYPEAAACYGRAIT-----------------RNPLVAVYYTNRAL 46 Query: 239 CLIKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPDDK 298 C +K+++ ++A+ C L + ++ KA F G+ + E+ D A + ++A A + + Sbjct: 47 CYLKMQQPEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSLAKEQR 106 >2Y4T-A nrPDB Length = 450 Score = 65.9 bits (159), Expect = 2e-11, Method: Composition-based stats. Identities = 40/196 (20%), Positives = 70/196 (35%), Gaps = 23/196 (11%) Query: 147 ADLLYEV--EVIGFDETKEGKARSD-----MTVEERIGAADRRKMDGNSLFKEEKLEEAM 199 + L Y++ + E +E +++ ++ L ++ + +A Sbjct: 218 STLYYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIESAEELIRDGRYTDAT 277 Query: 200 QQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAACLIKLKRYDEAIGHCNIVLTE 259 +YE + + + K + I C K ++ EAI C+ VL Sbjct: 278 SKYESVMKTEPSIAEYTVRSKER-------------ICHCFSKDEKPVEAIRVCSEVLQM 324 Query: 260 EEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPDDKAIRRELRALAEQEKALYQKQK 319 E N AL R +A D A D+ AQ++ +D+ IR L + L Q QK Sbjct: 325 EPDNVNALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQQIREGLEKAQ---RLLKQSQK 381 Query: 320 EMYKGIFKGKDEGGAK 335 Y I K + Sbjct: 382 RDYYKILGVKRNAKKQ 397 Score = 51.3 bits (121), Expect = 6e-07, Method: Composition-based stats. Identities = 27/167 (16%), Positives = 58/167 (34%), Gaps = 5/167 (2%) Query: 187 NSLFKE-EKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAACLIKLKR 245 N F+ +E+ ++ + +A G + A + + + Sbjct: 17 NLYFQSMADVEKHLELGKKLLAA-GQLADALSQFHAAVDGDPDNYIAYYRRATVFLAMGK 75 Query: 246 YDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPDDKAIRRELR 305 A+ V+ + A +RG + G++D A DDF+K K P + + Sbjct: 76 SKAALPDLTKVIQLKMDFTAARLQRGHLLLKQGKLDEAEDDFKKVLKSNPSENEEKEAQS 135 Query: 306 ALAEQEKALYQKQKEMYKGIFKGKDEGGAKSKSLFWLIVLWQWFVSL 352 L + ++ + + + F D A + L ++ + W L Sbjct: 136 QLIKSDEMQRLRSQAL--NAFGSGDYTAAIA-FLDKILEVCVWDAEL 179 >6H3J-B nrPDB Length = 176 Score = 61.3 bits (147), Expect = 6e-10, Method: Composition-based stats. Identities = 23/96 (23%), Positives = 42/96 (43%), Gaps = 10/96 (10%) Query: 64 PSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIGVASMKSGERAL 123 P+ S + Y+ + N + F+++ E L + G G+ +KSG Sbjct: 91 PTLNSNITVIYKGYFTNGKV-FDEST-EGVSYSLRT-----LIPGWKEGIPLLKSGGEIQ 143 Query: 124 VHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFD 159 + V L YG GN + VP A L++E+ ++ + Sbjct: 144 LFVPAHLGYGSNGNKT---VPGGAVLIFEITLVSVN 176 >2KFW-A nrPDB Length = 196 Score = 59.8 bits (143), Expect = 2e-09, Method: Composition-based stats. Identities = 31/143 (21%), Positives = 57/143 (39%), Gaps = 14/143 (9%) Query: 63 KPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIGVASMKSGERA 122 K +K L Y+ T++ E P++ + G ++GL + + G++ Sbjct: 2 KVAKDLVVSLAYQVRTEDGVLVDESPVS--APLDYLHG-HGSLISGLETALEGHEVGDKF 58 Query: 123 LVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIG-----FDETKEGKARSDMTVEERIG 177 V VG AYG+ VP D+ V+ + ET +G ++T E Sbjct: 59 DVAVGANDAYGQYDENLVQRVP--KDVFMGVDELQVGMRFLAETDQGPVPVEITAVED-- 114 Query: 178 AADRRKMDGNSLFKEEKLEEAMQ 200 D +DGN + + L+ ++ Sbjct: 115 --DHVVVDGNHMLAGQNLKFNVE 135 >2K8I-A nrPDB Length = 171 Score = 59.8 bits (143), Expect = 2e-09, Method: Composition-based stats. Identities = 31/143 (21%), Positives = 57/143 (39%), Gaps = 14/143 (9%) Query: 63 KPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIGVASMKSGERA 122 K +K L Y+ T++ E P++ + G ++GL + + G++ Sbjct: 2 KVAKDLVVSLAYQVRTEDGVLVDESPVS--APLDYLHG-HGSLISGLETALEGHEVGDKF 58 Query: 123 LVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIG-----FDETKEGKARSDMTVEERIG 177 V VG AYG+ VP D+ V+ + ET +G ++T E Sbjct: 59 DVAVGANDAYGQYDENLVQRVP--KDVFMGVDELQVGMRFLAETDQGPVPVEITAVED-- 114 Query: 178 AADRRKMDGNSLFKEEKLEEAMQ 200 D +DGN + + L+ ++ Sbjct: 115 --DHVVVDGNHMLAGQNLKFNVE 135 >2GW1-A nrPDB Length = 514 Score = 58.6 bits (140), Expect = 5e-09, Method: Composition-based stats. Identities = 30/148 (20%), Positives = 51/148 (34%), Gaps = 21/148 (14%) Query: 174 ERIGAADRRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCH 233 E+ A K GN F+ +K ++A++ Y A+ L + Sbjct: 1 EKDKYALALKDKGNQFFRNKKYDDAIKYYNWALE------------------LKEDPVFY 42 Query: 234 LNIAACLIKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKY 293 N++AC + + + + L + K L RR A LG+ A D Sbjct: 43 SNLSACYVSVGDLKKVVEMSTKALELKPDYSKVLLRRASANEGLGKFADAMFDL-SVLSL 101 Query: 294 APD--DKAIRRELRALAEQEKALYQKQK 319 D D +I L ++ K+K Sbjct: 102 NGDFNDASIEPMLERNLNKQAMSKLKEK 129 Score = 50.5 bits (119), Expect = 1e-06, Method: Composition-based stats. Identities = 20/118 (16%), Positives = 44/118 (37%) Query: 202 YEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAACLIKLKRYDEAIGHCNIVLTEEE 261 + ++ +D + + + L + ++ +A + E + + L + Sbjct: 242 HTGIFKFLKNDPLGAHEDIKKAIELFPRVNSYIYMALIMADRNDSTEYYNYFDKALKLDS 301 Query: 262 KNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPDDKAIRRELRALAEQEKALYQKQK 319 N + RG+ L D A DF KA++ P++ +L LA +E + Sbjct: 302 NNSSVYYHRGQMNFILQNYDQAGKDFDKAKELDPENIFPYIQLACLAYRENKFDDCET 359 Score = 29.4 bits (64), Expect = 2.7, Method: Composition-based stats. Identities = 23/128 (17%), Positives = 48/128 (37%), Gaps = 15/128 (11%) Query: 192 EEKLEEAMQQYEMAIAYMG--DDFMFQLYGKYQDMALAVKNPCHLNIAACLIKLKRYDEA 249 + ++A++QY++AI D + L +NP N + EA Sbjct: 385 KNDFDKALKQYDLAIELENKLDGIYVGIAPLVGKATLLTRNPTVEN----------FIEA 434 Query: 250 IGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPDDKAIRRELRALAE 309 + ++ +A + K + +D A F ++ A + + +L+A+ Sbjct: 435 TNLLEKASKLDPRSEQAKIGLAQMKLQQEDIDEAITLFEESADLA---RTMEEKLQAITF 491 Query: 310 QEKALYQK 317 E A Q+ Sbjct: 492 AEAAKVQQ 499 >2LKN-A nrPDB Length = 165 Score = 57.5 bits (137), Expect = 9e-09, Method: Composition-based stats. Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 4/90 (4%) Query: 41 DSEAEVLDEKVSKQIIKEGHGSKP--SKYSTCFLHY-RAWTKNSQHKFEDTWHEQQPIEL 97 D A + ++ + K++I+EG G P + HY + + +D+ +P+EL Sbjct: 2 DIIARLREDGIQKRVIQEGRGELPDFQDGTKATFHYRTLHSDDEGTVLDDSRARGKPMEL 61 Query: 98 VLGKEKKELAGLAIGVASMKSGERALVHVG 127 ++GK+ K L V +M+ GE A Sbjct: 62 IIGKKFK-LPVWETIVCTMREGEIAQFLCD 90 >6B85-J nrPDB Length = 223 Score = 56.7 bits (135), Expect = 2e-08, Method: Composition-based stats. Identities = 32/130 (24%), Positives = 54/130 (41%), Gaps = 18/130 (13%) Query: 198 AMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAACLIKLKRYDEAIGHCNIVL 257 A + Y+ AI +D + L + + L KLKR DEA + Sbjct: 100 AAEAYKKAIELDPNDAL-----------------AWLLLGSVLEKLKRLDEAAEAYKKAI 142 Query: 258 TEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPDDKAIRRELRALAEQEKALYQK 317 + + A GK +LG++D A + ++KA + P+D +EL + E+ L + Sbjct: 143 ELKPNDASAWKELGKVLEKLGRLDEAAEAYKKAIELDPEDAEAWKELGKVLEKLGRL-DE 201 Query: 318 QKEMYKGIFK 327 E YK + Sbjct: 202 AAEAYKKAIE 211 Score = 47.8 bits (112), Expect = 7e-06, Method: Composition-based stats. Identities = 18/87 (20%), Positives = 37/87 (42%), Gaps = 2/87 (2%) Query: 249 AIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPDDKAIRRELRALA 308 A + + + A G +L ++D A + ++KA + P+D + +EL + Sbjct: 100 AAEAYKKAIELDPNDALAWLLLGSVLEKLKRLDEAAEAYKKAIELKPNDASAWKELGKVL 159 Query: 309 EQEKALYQKQKEMYKGIFK-GKDEGGA 334 E+ L + E YK + ++ A Sbjct: 160 EKLGRL-DEAAEAYKKAIELDPEDAEA 185 >4JYS-A nrPDB Length = 138 Score = 55.9 bits (133), Expect = 3e-08, Method: Composition-based stats. Identities = 31/144 (21%), Positives = 57/144 (39%), Gaps = 14/144 (9%) Query: 38 PKVDSEAEVLDEKVSKQIIKEGHGSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIEL 97 P V +E+ + + + +G G + ++HY+ T N T++ P ++ Sbjct: 7 PYVKTES-----GILYKDLIDGEGDPIEEGDIVYIHYQGKTTNDFRIIHSTFNSIIPPKI 61 Query: 98 VLGKEKKE-LAGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVI 156 G+ ++ + + V MK R V LAY FP+ P LLYE++V+ Sbjct: 62 RAGQYDQKHIRAIYEIVIGMKKHTRRQCVVPPHLAY----PNHFPSQP----LLYEIDVV 113 Query: 157 GFDETKEGKARSDMTVEERIGAAD 180 + VE++I Sbjct: 114 KVVKKDSQGKTFIEKVEQKIDQIR 137 >1IX5-A nrPDB Length = 151 Score = 54.8 bits (130), Expect = 6e-08, Method: Composition-based stats. Identities = 28/154 (18%), Positives = 49/154 (31%), Gaps = 31/154 (20%) Query: 66 KYSTCFLHYRAWTKNSQHKFEDTWHE-------------QQPIELVLGKEKKELAGLAIG 112 K + Y ++ F+ + E +P+E V+G E + + G Sbjct: 4 KGVKIKVDYIGKLESGDV-FDTSIEEVAKEAGIYAPDREYEPLEFVVG-EGQLIQGFEEA 61 Query: 113 VASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETKEGKARSDMTV 172 V M+ G+ V + E AYG +P A F E + + Sbjct: 62 VLDMEVGDEKTVKIPAEKAYGNRNEMLIQKIPRDA----------FKEADFEPEEGMVIL 111 Query: 173 EERIGAA------DRRKMDGNSLFKEEKLEEAMQ 200 E I A + +D N + L ++ Sbjct: 112 AEGIPATITEVTDNEVTLDFNHELAGKDLVFTIK 145 >4ODP-A nrPDB Length = 110 Score = 52.1 bits (123), Expect = 4e-07, Method: Composition-based stats. Identities = 22/97 (22%), Positives = 35/97 (36%), Gaps = 8/97 (8%) Query: 65 SKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIGVASMKSGERALV 124 + R + + Q + + G + GL + + GE Sbjct: 2 KVGQDKVVTIRYTLQVEGEVLD-----QGELSYLHGHRNL-IPGLEEALEGREEGEAFQA 55 Query: 125 HVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDET 161 HV E AYG G+ +PP A L ++VEV+ E Sbjct: 56 HVPAEKAYGATGHPGI--IPPHATLDFQVEVVKVREA 90 >5LVV-A nrPDB Length = 749 Score = 51.7 bits (122), Expect = 5e-07, Method: Composition-based stats. Identities = 28/172 (16%), Positives = 56/172 (32%), Gaps = 26/172 (15%) Query: 178 AADRRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIA 237 A+ ++ GN +EEA++ Y A+ + H N+A Sbjct: 36 LANIKREQGN-------IEEAVRLYRKALEVFPEFA-----------------AAHSNLA 71 Query: 238 ACLIKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPDD 297 + L + + EA+ H + A G E+ + A + +A + P Sbjct: 72 SVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAF 131 Query: 298 KAIRRELRALAEQEKALYQKQKEMYKGIFKGKDEGG-AKSKSLFWLIVLWQW 348 L ++ ++ + Y+ K K + A L ++ W Sbjct: 132 ADAHSNLASI-HKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDW 182 Score = 33.2 bits (74), Expect = 0.18, Method: Composition-based stats. Identities = 10/64 (15%), Positives = 23/64 (35%) Query: 232 CHLNIAACLIKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQ 291 N+A + +EA+ L + A + G++ A +++A Sbjct: 32 SLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAI 91 Query: 292 KYAP 295 + +P Sbjct: 92 RISP 95 >5AEM-A nrPDB Length = 447 Score = 50.2 bits (118), Expect = 1e-06, Method: Composition-based stats. Identities = 38/175 (21%), Positives = 64/175 (36%), Gaps = 19/175 (10%) Query: 187 NSLFKEEKLEEAMQQYEMAIAYMGDDFM--------FQLYGKYQDMALAVKNPCHLN--- 235 N F L+ A + + I +F +QL G+ D + HLN Sbjct: 17 NEAFVRNDLQVAERLFNEVIKKDARNFAAYETLGDIYQLQGRLNDCCNSWFLAAHLNASD 76 Query: 236 ------IAACLIKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRK 289 +A L +AI + V++ ++++RR + GQ+ A D F++ Sbjct: 77 WEFWKIVAILSADLDHVRQAIYCFSRVISLNPMEWESIYRRSMLYKKTGQLARALDGFQR 136 Query: 290 AQKYAPDDKAIRRELRALAEQEKALYQKQKEMYKGIFKGK-DEGGAKSKSLFWLI 343 Y P D I REL L + E+Y +F + A +L + Sbjct: 137 LYMYNPYDANILRELAILYVDYDRIEDSI-ELYMKVFNANVERREAILAALENAL 190 >3PRA-A nrPDB Length = 157 Score = 48.6 bits (114), Expect = 4e-06, Method: Composition-based stats. Identities = 18/94 (19%), Positives = 30/94 (31%), Gaps = 20/94 (21%) Query: 66 KYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLG---------------KEKKELAGLA 110 K + Y + + + F+ T + + G E + L GL Sbjct: 4 KGKMVKISYDGYV-DGKL-FDTT---NEELAKKEGIYNPAMIYGPVAIFAGEGQVLPGLD 58 Query: 111 IGVASMKSGERALVHVGWELAYGKEGNFSFPNVP 144 + M GE V + E A+GK +P Sbjct: 59 EAILEMDVGEEREVVLPPEKAFGKRDPSKIKLIP 92 >5KHR-J nrPDB Length = 620 Score = 47.5 bits (111), Expect = 9e-06, Method: Composition-based stats. Identities = 25/126 (19%), Positives = 43/126 (34%), Gaps = 8/126 (6%) Query: 184 MDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAACLIKL 243 G F+ + + A + + A+ + K++ P N+ KL Sbjct: 407 EVGVVAFQNGEWKTAEKWFLDALEKIKAIGNEVTVDKWE--------PLLNNLGHVCRKL 458 Query: 244 KRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPDDKAIRRE 303 K+Y EA+ + L +N G + +G ++A D F A DD Sbjct: 459 KKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTM 518 Query: 304 LRALAE 309 L E Sbjct: 519 LGHCIE 524 >3PRB-A nrPDB Length = 231 Score = 47.1 bits (110), Expect = 1e-05, Method: Composition-based stats. Identities = 18/91 (19%), Positives = 29/91 (31%), Gaps = 14/91 (15%) Query: 66 KYSTCFLHYRAWTKNSQHKFEDTWHEQQP------------IELVLGKEKKELAGLAIGV 113 K + Y + + + F+ T E + E + L GL + Sbjct: 4 KGKMVKISYDGYV-DGKL-FDTTNEELAKKEGIYNPAMIYGPVAIFAGEGQVLPGLDEAI 61 Query: 114 ASMKSGERALVHVGWELAYGKEGNFSFPNVP 144 M GE V + E A+GK +P Sbjct: 62 LEMDVGEEREVVLPPEKAFGKRDPSKIKLIP 92 >5A01-A nrPDB Length = 710 Score = 46.3 bits (108), Expect = 2e-05, Method: Composition-based stats. Identities = 29/172 (16%), Positives = 56/172 (32%), Gaps = 26/172 (15%) Query: 178 AADRRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIA 237 A+ ++ G +EEA + Y A+ D H N+A Sbjct: 13 LANIKREQGY-------IEEATRLYLKALEVFPDFA-----------------AAHSNLA 48 Query: 238 ACLIKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPDD 297 + L + + EA+ H + + A G EL + A + +A + P Sbjct: 49 SVLQQQGKLKEALMHYKEAIRIQPTFADAYSNMGNTLKELQDVSGALQCYTRAIQINPAF 108 Query: 298 KAIRRELRALAEQEKALYQKQKEMYKGIFKGKDEGG-AKSKSLFWLIVLWQW 348 L ++ ++ + + Y+ K K + A L ++ W Sbjct: 109 ADAHSNLASI-HKDSGNIPEAIQSYRTALKLKPDFPDAYCNLAHCLQIVCDW 159 Score = 32.4 bits (72), Expect = 0.32, Method: Composition-based stats. Identities = 10/64 (15%), Positives = 20/64 (31%) Query: 232 CHLNIAACLIKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQ 291 N+A + +EA L A + G++ A +++A Sbjct: 9 SLNNLANIKREQGYIEEATRLYLKALEVFPDFAAAHSNLASVLQQQGKLKEALMHYKEAI 68 Query: 292 KYAP 295 + P Sbjct: 69 RIQP 72 >4DT4-A nrPDB Length = 169 Score = 46.3 bits (108), Expect = 2e-05, Method: Composition-based stats. Identities = 13/72 (18%), Positives = 25/72 (34%), Gaps = 2/72 (2%) Query: 62 SKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIGVASMKSGER 121 S +H+ + E T + +P LG GL + +K G++ Sbjct: 23 ESVQSNSAVLVHFTLKLDDGTTA-ESTRNNGKPALFRLGDASLS-EGLEQHLLGLKVGDK 80 Query: 122 ALVHVGWELAYG 133 + + A+G Sbjct: 81 TTFSLEPDAAFG 92 >2M2A-A nrPDB Length = 148 Score = 46.3 bits (108), Expect = 2e-05, Method: Composition-based stats. Identities = 13/72 (18%), Positives = 25/72 (34%), Gaps = 2/72 (2%) Query: 62 SKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIGVASMKSGER 121 S +H+ + E T + +P LG GL + +K G++ Sbjct: 3 ESVQSNSAVLVHFTLKLDDGTTA-ESTRNNGKPALFRLGDASLS-EGLEQHLLGLKVGDK 60 Query: 122 ALVHVGWELAYG 133 + + A+G Sbjct: 61 TTFSLEPDAAFG 72 >5G04-F nrPDB Length = 824 Score = 45.1 bits (105), Expect = 5e-05, Method: Composition-based stats. Identities = 22/125 (17%), Positives = 45/125 (36%), Gaps = 17/125 (13%) Query: 186 GNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAACLIKLKR 245 G +K+EK A ++ A+ + L CH I LK+ Sbjct: 642 GMIYYKQEKFSLAEMHFQKAL----------DINPQSSVLL-----CH--IGVVQHALKK 684 Query: 246 YDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPDDKAIRRELR 305 ++A+ N + + KNP F R + SA + + ++ P + + + Sbjct: 685 SEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIG 744 Query: 306 ALAEQ 310 + ++ Sbjct: 745 KVYKK 749 Score = 34.0 bits (76), Expect = 0.094, Method: Composition-based stats. Identities = 17/100 (17%), Positives = 29/100 (29%) Query: 196 EEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAACLIKLKRYDEAIGHCNI 255 E M+ Y + ++ D + K C + +D AI Sbjct: 533 VEGMEIYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQR 592 Query: 256 VLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAP 295 + + A G ++D A FR A + P Sbjct: 593 AIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNP 632 >5U9A-A nrPDB Length = 169 Score = 44.8 bits (104), Expect = 5e-05, Method: Composition-based stats. Identities = 21/82 (25%), Positives = 34/82 (41%), Gaps = 4/82 (4%) Query: 49 EKVSKQIIKEGHGSKPS--KYSTCFLHYRAWTKNSQH-KFEDTWHEQQPIELVLGKEKKE 105 E V K I+ G G P+ S H+R + + +D+ QP+ +++G K Sbjct: 18 EGVKKTILHGGTGELPNFITGSRVIFHFRTMKCDEERTVIDDSRQVGQPMHIIIGNMFK- 76 Query: 106 LAGLAIGVASMKSGERALVHVG 127 L I + SM+ E A Sbjct: 77 LEVWEILLTSMRVHEVAEFWCD 98 >1W3B-A nrPDB Length = 388 Score = 44.8 bits (104), Expect = 7e-05, Method: Composition-based stats. Identities = 27/155 (17%), Positives = 53/155 (34%), Gaps = 19/155 (12%) Query: 144 PPMADLLYEVEVIGF--DETKEGKARSDMTVEERIGAADRRKMDGNSLFKEEKLEEAMQQ 201 P +L + I F S + +++ A+ GN + +L+EA++ Sbjct: 30 PDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEH 89 Query: 202 YEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAACLIKLKRYDEAIGHCNIVLTEEE 261 Y A+ D ++N+AA L+ + A+ L Sbjct: 90 YRHALRLKPDFIDG-----------------YINLAAALVAAGDMEGAVQAYVSALQYNP 132 Query: 262 KNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPD 296 G LG+++ A+ + KA + P+ Sbjct: 133 DLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPN 167 Score = 40.1 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 28/157 (17%), Positives = 48/157 (30%), Gaps = 18/157 (11%) Query: 188 SLFKEEKLEEAMQQYEMAIAYMGD---------DFMFQLYGKYQDMALAVKN-------- 230 +L +E A+Q Y A+ Y D + + L + A +K Sbjct: 110 ALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFA 169 Query: 231 PCHLNIAACLIKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKA 290 N+ AI H +T + A G E D A + +A Sbjct: 170 VAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRA 229 Query: 291 QKYAPDDKAIRRELRALAEQEKALYQKQKEMYKGIFK 327 +P+ + L A E+ L + Y+ + Sbjct: 230 LSLSPNHAVVHGNL-ACVYYEQGLIDLAIDTYRRAIE 265 Score = 38.2 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 18/136 (13%), Positives = 43/136 (31%), Gaps = 20/136 (14%) Query: 180 DRRKMDGN---SLFKEEKLEEAMQQYEMAI--------------AYMGDDFMFQLYGKYQ 222 + + GN +++ ++ A+ Y AI + + Sbjct: 235 NHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCY 294 Query: 223 DMALAVKNP---CHLNIAACLIKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQ 279 + AL + N+A + +EA+ L + A + G+ Sbjct: 295 NTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGK 354 Query: 280 MDSARDDFRKAQKYAP 295 + A +++A + +P Sbjct: 355 LQEALMHYKEAIRISP 370 Score = 29.4 bits (64), Expect = 2.5, Method: Composition-based stats. Identities = 17/86 (19%), Positives = 25/86 (29%), Gaps = 34/86 (39%) Query: 245 RYDEAIGHCNIVLTEEEKNPKALF---------RR------------------------- 270 ++ A HC + +E N L RR Sbjct: 14 DFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNL 73 Query: 271 GKAKAELGQMDSARDDFRKAQKYAPD 296 G E GQ+ A + +R A + PD Sbjct: 74 GNVYKERGQLQEAIEHYRHALRLKPD 99 >2KR7-A nrPDB Length = 151 Score = 43.6 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 25/128 (19%), Positives = 46/128 (35%), Gaps = 3/128 (2%) Query: 68 STCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIGVASMKSGERALVHVG 127 + Y + S + ++P+E ++G + +AGL V + GE V + Sbjct: 11 QAALIEYEVREQGSSIVLDSNIS-KEPLEFIIGT-NQIIAGLEKAVLKAQIGEWEEVVIA 68 Query: 128 WELAYGKEGNFSFPNVPPMADLLYEVEVIGFDETKEGKARSDMTVEERIGAADRRKMDGN 187 E AYG + VP E+E G + + + + +A +D N Sbjct: 69 PEEAYGVYESSYLQEVPRDQFEGIELE-KGMSVFGQTEDNQTIQAIIKDFSATHVMVDYN 127 Query: 188 SLFKEEKL 195 + L Sbjct: 128 HPLAGKTL 135 >5FZQ-A nrPDB Length = 131 Score = 42.4 bits (98), Expect = 3e-04, Method: Composition-based stats. Identities = 23/94 (24%), Positives = 37/94 (39%) Query: 230 NPCHLNIAACLIKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRK 289 N+A L + + +EAI + ++ + N K L A+ G+ + A RK Sbjct: 5 IKTLSNLANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLANLLAQEGKAEEAIKYMRK 64 Query: 290 AQKYAPDDKAIRRELRALAEQEKALYQKQKEMYK 323 A P++ L L QE + K M K Sbjct: 65 AVSLDPNNIKTLSNLAVLLAQEGKAEEAIKYMRK 98 Score = 36.3 bits (82), Expect = 0.024, Method: Composition-based stats. Identities = 26/115 (22%), Positives = 45/115 (39%), Gaps = 19/115 (16%) Query: 187 NSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAACLIKLKRY 246 N L +E K EEA++ A++ ++ N+A L + + Sbjct: 13 NLLAQEGKAEEAIKYMRKAVSLDPNN-----------------IKTLSNLANLLAQEGKA 55 Query: 247 DEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPDDKAIR 301 +EAI + ++ + N K L A+ G+ + A RKA DKA + Sbjct: 56 EEAIKYMRKAVSLDPNNIKTLSNLAVLLAQEGKAEEAIKYMRKAVSLI--DKAAK 108 Score = 31.3 bits (69), Expect = 0.73, Method: Composition-based stats. Identities = 21/85 (24%), Positives = 30/85 (35%), Gaps = 4/85 (4%) Query: 261 EKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPDDKAIRRELRALAEQEKALYQKQKE 320 + K L A+ G+ + A RKA P++ L L A K +E Sbjct: 2 GNSIKTLSNLANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLANLL----AQEGKAEE 57 Query: 321 MYKGIFKGKDEGGAKSKSLFWLIVL 345 K + K K+L L VL Sbjct: 58 AIKYMRKAVSLDPNNIKTLSNLAVL 82 >4CGU-A nrPDB Length = 112 Score = 41.3 bits (95), Expect = 6e-04, Method: Composition-based stats. Identities = 27/111 (24%), Positives = 40/111 (36%), Gaps = 23/111 (20%) Query: 176 IGAADRRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLN 235 + +++K GNSLFK+ EA+ Y+ I A + N Sbjct: 2 MSQFEKQKEQGNSLFKQGLYREAVHCYDQLIT-----------------AQPQNPVGYSN 44 Query: 236 IAACLIKLKRYDEAIGHCNIVL------TEEEKNPKALFRRGKAKAELGQM 280 A LIKL Y +AI C L K +R A+ +G + Sbjct: 45 KAMALIKLGEYTQAIQMCQQGLRYTSTAEHVAIRSKLQYRLELAQGAVGSV 95 Score = 35.5 bits (80), Expect = 0.035, Method: Composition-based stats. Identities = 17/69 (24%), Positives = 32/69 (46%), Gaps = 2/69 (2%) Query: 239 CLIKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPDDK 298 L K Y EA+ + ++T + +NP + A +LG+ A ++ +Y + Sbjct: 14 SLFKQGLYREAVHCYDQLITAQPQNPVGYSNKAMALIKLGEYTQAIQMCQQGLRYTSTAE 73 Query: 299 --AIRRELR 305 AIR +L+ Sbjct: 74 HVAIRSKLQ 82 >5WQL-B nrPDB Length = 278 Score = 40.9 bits (94), Expect = 8e-04, Method: Composition-based stats. Identities = 36/211 (17%), Positives = 74/211 (35%), Gaps = 13/211 (6%) Query: 157 GFDETKEGKARSDMTVEERIGAADRRKMDGNSLFKEEKLEEAMQQYEMAIAY--MGDDFM 214 + +++ T+++ + A ++ + ++ E A YE + Y +G + Sbjct: 7 SWRKSEVLAVPLQPTLQQEVILARMEQILASRALTDD--ERAQLLYERGVLYDSLGLRAL 64 Query: 215 FQLYGKYQDMALAVKNPCHLNIAACLIKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAK 274 + + L + +D A + VL + A RG A Sbjct: 65 ARNDFSQALAIRPDMPEVFNYLGIYLTQAGNFDAAYEAFDSVLELDPTYNYAHLNRGIAL 124 Query: 275 AELGQMDSARDDFRKAQKYAPDDKAIRRELRALAEQEKALYQKQKEMYKGIFKGKDEGGA 334 G+ A+DD + P+D L ++ K+ + K F+ D+ Sbjct: 125 YYGGRDKLAQDDLLAFYQDDPNDPFRSLWLYLAEQKLDEKQAKE--VLKQHFEKSDK--- 179 Query: 335 KSKSLFWLIVLWQWFVSLFSRIFRRHRVKAD 365 + W IV ++++ S R+KAD Sbjct: 180 --EQWGWNIV--EFYLGNISEQTLMERLKAD 206 >1HH8-A nrPDB Length = 213 Score = 40.1 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 20/116 (17%), Positives = 38/116 (32%), Gaps = 1/116 (0%) Query: 195 LEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAACLIKLKRYDEAIGHCN 254 L EA+ + + + + C NI LK EA Sbjct: 3 LVEAISLWNEGVLAADKKDWKGALDAFSAVQDPHSRICF-NIGCMYTILKNMTEAEKAFT 61 Query: 255 IVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPDDKAIRRELRALAEQ 310 + ++ A F+RG + + D A D ++A ++ I ++ L + Sbjct: 62 RSINRDKHLAVAYFQRGMLYYQTEKYDLAIKDLKEALIQLRGNQLIDYKILGLQFK 117 >5NNP-A nrPDB Length = 745 Score = 39.4 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 24/133 (18%), Positives = 48/133 (36%), Gaps = 2/133 (1%) Query: 208 YMGDDFMFQLYGKYQDMALAVKNPCHLNIAACLIKLK-RYDEAIGHCNIVLTEEEKNPKA 266 Y + L Q + K+ +++ A ++ + + +EA LT + K+ Sbjct: 21 YEDKQYKRGLKAAEQILKKNPKHGDTMSMKALILNAQGKTEEAFALAKEALTIDMKSYIC 80 Query: 267 LFRRGKAKAELGQMDSARDDFRKAQKYAPDDKAIRRELRALAEQEKALYQKQKEMYKGIF 326 G D A ++ A K P+ I+R+L L Q + Y + + Sbjct: 81 WHVYGILYRTNKNFDEAIKAYKFALKLEPESHQIQRDLAVLQIQMRD-YAGYVQSRLNML 139 Query: 327 KGKDEGGAKSKSL 339 K + + +L Sbjct: 140 KARPQIRQNWTAL 152 Score = 37.4 bits (85), Expect = 0.009, Method: Composition-based stats. Identities = 24/163 (14%), Positives = 48/163 (29%), Gaps = 9/163 (5%) Query: 190 FKEEKLEEAMQQY-EMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAACLIKLKRYDE 248 FK+E L ++Y + D G A H N + Sbjct: 337 FKKETLASLAEEYLNEYVNARPSDNQADGDGSKGKGAALYYLAQHYNYYMS----RDLTR 392 Query: 249 AIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPDDKAIRRELRALA 308 A+ + + + KN + + G + A + A+ P D+ I + Sbjct: 393 ALEYVEKAIELDPKNVDFHMTKARIFKHQGDLAKAAETMDYARSLDPKDRYINSKAAKYQ 452 Query: 309 EQEKALYQKQKEMYKGIFKGKDEGGAKSKSLFWLIVLWQWFVS 351 + +K + + GG + + WF++ Sbjct: 453 LRNNE-NEKALATMGLFTRAETAGGPLADLTD---MQCIWFLT 491 >4JHR-A nrPDB Length = 333 Score = 37.4 bits (85), Expect = 0.010, Method: Composition-based stats. Identities = 26/149 (17%), Positives = 54/149 (36%), Gaps = 20/149 (13%) Query: 155 VIGFDETKEGKARSDMTVEERIGAADRRKMD---GNSLFKEEKLEEAMQQYEMAIAYMGD 211 + F + + + +E A R+ GN+ + E A + Y+ + Sbjct: 124 LGNFRDAVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTL----- 178 Query: 212 DFMFQLYGKYQDMALAVKNPCHLNIAACLIKLKRYDEAIGHCNIVLTEEEK------NPK 265 L + +D A+ + C+ ++ L+ Y++AI + L ++ + Sbjct: 179 ----LLARQLKDRAVEAQ-SCY-SLGNTYTLLQDYEKAIDYHLKHLAIAQELKDRIGEGR 232 Query: 266 ALFRRGKAKAELGQMDSARDDFRKAQKYA 294 A + G A LG D A K + + Sbjct: 233 ACWSLGNAYTALGNHDQAMHFAEKHLEIS 261 Score = 35.9 bits (81), Expect = 0.026, Method: Composition-based stats. Identities = 29/147 (19%), Positives = 51/147 (34%), Gaps = 17/147 (11%) Query: 174 ERIGAADRRKMDGNSLFK---------EEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDM 224 +++G A GN + E + A+ D + L Sbjct: 46 DKVGEARALYNLGNVYHAKGKSFGCPGPQDTGEFPEDVRNALQAAVDLYEENLSLVTALG 105 Query: 225 ALAVKNPCHLNIAACLIKLKRYDEA-IGHCNIVLTEEEKNPKALFRR-----GKAKAELG 278 A + N+ L + +A I H +L +E KA RR G A LG Sbjct: 106 DRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLG 165 Query: 279 QMDSARDDFRKAQKYAPD--DKAIRRE 303 + ++A + ++K A D+A+ + Sbjct: 166 EFETASEYYKKTLLLARQLKDRAVEAQ 192 >6C95-A nrPDB Length = 866 Score = 37.4 bits (85), Expect = 0.010, Method: Composition-based stats. Identities = 19/139 (13%), Positives = 47/139 (33%), Gaps = 23/139 (16%) Query: 192 EEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAACLIKLKRYDEAIG 251 ++K +EA++ Y A+ + D+ +++ I+++ + Sbjct: 93 DKKYDEAIKCYRNALKWDKDN-----------------LQILRDLSLLQIQMRDLEGYRE 135 Query: 252 HCNIVLTEEEKNPKALFRRGKAKAELGQMDSA---RDDFRKAQKYAPDDKAIRRELRALA 308 +L + A L + A ++FRK Q+ +PD L Sbjct: 136 TRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQTSPDKVDYEYSELLLY 195 Query: 309 EQEKALYQKQKEMYKGIFK 327 + ++ +Y+ + Sbjct: 196 QN---QVLREAGLYREALE 211 Score = 27.4 bits (59), Expect = 9.0, Method: Composition-based stats. Identities = 23/122 (18%), Positives = 45/122 (36%), Gaps = 18/122 (14%) Query: 199 MQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAACLIKLKRYDEAIGH------ 252 ++ YEMA + + Q + + + N L Y EA+ H Sbjct: 161 LEDYEMAAKILEEFRKTQQTSPDKVDYEYSELLLYQNQVLREAGL--YREALEHLCTYEK 218 Query: 253 --CNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPDDKAIRRELRALAEQ 310 C+ + EE +G+ +L +++ A D +R Q+ P++ A + L + Sbjct: 219 QICDKLAVEET--------KGELLLQLCRLEDAADVYRGLQERNPENWAYYKGLEKALKP 270 Query: 311 EK 312 Sbjct: 271 AN 272 >6N3Q-F nrPDB Length = 193 Score = 37.1 bits (84), Expect = 0.014, Method: Composition-based stats. Identities = 28/132 (21%), Positives = 48/132 (36%), Gaps = 3/132 (2%) Query: 184 MDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAACLIKL 243 G +++KL EA++ +AI Q L +++ CLI L Sbjct: 63 ESGMKNLQQKKLNEALKNVSLAIEMAQRKRAPWEAFAIQLPELHFMLRSKIDL--CLI-L 119 Query: 244 KRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPDDKAIRRE 303 ++ EA+ + +L P R+ +L Q + AR + AP+D +R Sbjct: 120 GKHLEALQDLDFLLGTGLIQPDVFVRKADCLLKLRQWEEARATCERGLALAPEDMKLRAL 179 Query: 304 LRALAEQEKALY 315 L A Sbjct: 180 LIETARNLAEYN 191 >5DSE-A nrPDB Length = 837 Score = 35.9 bits (81), Expect = 0.026, Method: Composition-based stats. Identities = 21/124 (16%), Positives = 38/124 (30%) Query: 196 EEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAACLIKLKRYDEAIGHCNI 255 A + E A++ + + L+ A I + + EA Sbjct: 656 SVAASRVEQALSEVASSLQSSAPKQGPLHPWMTLAQIWLHAAEVYIGIGKPAEATACTQE 715 Query: 256 VLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPDDKAIRRELRALAEQEKALY 315 + L+ RG+ G MD AR + +A +P + L + Q Sbjct: 716 AANLFPMSHNVLYMRGQIAELRGSMDEARRWYEEALAISPTHVKSMQRLALILHQLGRYS 775 Query: 316 QKQK 319 +K Sbjct: 776 LAEK 779 >5ZYQ-A nrPDB Length = 320 Score = 35.5 bits (80), Expect = 0.040, Method: Composition-based stats. Identities = 24/114 (21%), Positives = 38/114 (33%), Gaps = 10/114 (8%) Query: 230 NPCHLNIAACLIKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAK--AELGQMDSARDDF 287 P L A K Y A+ + L P A R G +L +++ AR F Sbjct: 163 IPALLGKACISFNKKDYRGALAYYKKALRTNPGCP-AEVRLGMGHCFVKLNKLEKARLAF 221 Query: 288 RKAQKYAPDDKAIRRELRALAEQEKALYQKQKEMYKGIF--KGKDEGGAKSKSL 339 +A + L L L K+ + + ++ G K+ SL Sbjct: 222 SRALELNSKCVGALVGLAVL-----ELNNKEADGSENLYFQSGSRFVQYKATSL 270 Score = 32.0 bits (71), Expect = 0.36, Method: Composition-based stats. Identities = 13/58 (22%), Positives = 23/58 (39%) Query: 239 CLIKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPD 296 CL++ + D+A + VL + N AL + A ++KA + P Sbjct: 138 CLLEGDKMDQADAQFHFVLNQSPNNIPALLGKACISFNKKDYRGALAYYKKALRTNPG 195 >5OJ8-A nrPDB Length = 255 Score = 35.1 bits (79), Expect = 0.053, Method: Composition-based stats. Identities = 24/143 (16%), Positives = 43/143 (30%), Gaps = 19/143 (13%) Query: 200 QQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAACLIKLKRYDEAIGHCNIVLTE 259 +Y+ A + D + K N+A K +Y EA C L Sbjct: 106 NKYKDAANLLND--ALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEI 163 Query: 260 --------EEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYA-----PDDKAI---RRE 303 K L G+ + +++A + PDD + + Sbjct: 164 REKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNN 223 Query: 304 LRALAEQEKALYQKQKEMYKGIF 326 L + ++ Q + +YK I Sbjct: 224 LASCYLKQGKFKQAET-LYKEIL 245 >5G04-X nrPDB Length = 599 Score = 35.1 bits (79), Expect = 0.053, Method: Composition-based stats. Identities = 24/126 (19%), Positives = 48/126 (38%), Gaps = 9/126 (7%) Query: 223 DMALAVKN---PCHLNIAACLIKLKRYDEAIGHCNIVLTEEEKNPKALFR-RGKAKAELG 278 D AL + + A L + ++Y++ I L + L R G + Sbjct: 466 DKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCV--LHRILGDFLVAVN 523 Query: 279 QMDSARDDFRKAQKYAPDDKAIRRELRALAEQEKALYQKQKEMYKGIFKGKDEG---GAK 335 + A D + A P+D+ ++ + ++E Q+E + +EG G+ Sbjct: 524 EYQEAMDQYSIALSLDPNDQKSLEGMQKMEKEESPTDATQEEDVDDMEGSGEEGDLEGSD 583 Query: 336 SKSLFW 341 S++ W Sbjct: 584 SEAAQW 589 Score = 31.7 bits (70), Expect = 0.53, Method: Composition-based stats. Identities = 15/82 (18%), Positives = 36/82 (43%), Gaps = 5/82 (6%) Query: 188 SLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAAC--LIKLKR 245 +L + +A+ + ++ + ++ ALA ++ C L+ L+ + Sbjct: 468 ALTQRPDYIKAVVKKAELLS---REQKYEDGIALLRNALANQSDCVLHRILGDFLVAVNE 524 Query: 246 YDEAIGHCNIVLTEEEKNPKAL 267 Y EA+ +I L+ + + K+L Sbjct: 525 YQEAMDQYSIALSLDPNDQKSL 546 >4I1A-A nrPDB Length = 391 Score = 34.7 bits (78), Expect = 0.061, Method: Composition-based stats. Identities = 32/140 (22%), Positives = 58/140 (41%), Gaps = 20/140 (14%) Query: 194 KLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAACLIKLKRYDEAIGHC 253 + E A++Q+ ++ K ++ + H+NI C +LK Y +A H Sbjct: 199 EYERALEQFLKSLE----------ISKESNI-EHLIAMSHMNIGICYDELKEYKKASQHL 247 Query: 254 NIVLTEEEKN-----PKALFRRGKAKAELGQMDSARDDFRKAQKYAPDDKAIRRELRALA 308 + L EK+ K LF +A+ + A FRK + A DK+ +E A Sbjct: 248 ILALEIFEKSKHSFLTKTLFTLTYVEAKQQNYNVALIYFRKGRFIA--DKSDDKEYSAKF 305 Query: 309 EQEKALY--QKQKEMYKGIF 326 + + L+ + ++ K F Sbjct: 306 KILEGLFFSDGETQLIKNAF 325 >3NF1-A nrPDB Length = 311 Score = 34.4 bits (77), Expect = 0.086, Method: Composition-based stats. Identities = 22/143 (15%), Positives = 41/143 (28%), Gaps = 19/143 (13%) Query: 200 QQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAACLIKLKRYDEAIGHCNIVLTE 259 +Y+ A + D + K N+A K +Y EA C L Sbjct: 83 NKYKDAANLLND--ALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEI 140 Query: 260 --------EEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYA--------PDDKAIRRE 303 K L G+ + +++A + P+ + Sbjct: 141 REKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNN 200 Query: 304 LRALAEQEKALYQKQKEMYKGIF 326 L + ++ Q + +YK I Sbjct: 201 LASCYLKQGKFKQAET-LYKEIL 222 >4UZY-A nrPDB Length = 651 Score = 34.0 bits (76), Expect = 0.096, Method: Composition-based stats. Identities = 19/79 (24%), Positives = 30/79 (37%), Gaps = 17/79 (21%) Query: 180 DRRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAAC 239 D G +FKE K E A Q++ A+ +G + NIA C Sbjct: 148 DTMVNTGCIMFKEGKFEAARQKFNDAVQALG-----------------YQPELLYNIALC 190 Query: 240 LIKLKRYDEAIGHCNIVLT 258 K K++ A+ H ++ Sbjct: 191 YYKTKQFGPALKHLAEIIE 209 >3CGM-A nrPDB Length = 158 Score = 34.0 bits (76), Expect = 0.11, Method: Composition-based stats. Identities = 16/83 (19%), Positives = 24/83 (28%), Gaps = 6/83 (7%) Query: 65 SKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIGVASMKSGERALV 124 + R + + Q + + G + GL + + GE Sbjct: 2 KVGQDKVVTIRYTLQVEGEVLD-----QGELSYLHGHRNL-IPGLEEALEGREEGEAFQA 55 Query: 125 HVGWELAYGKEGNFSFPNVPPMA 147 HV E AYG VP A Sbjct: 56 HVPAEKAYGPHDPEGVQVVPLSA 78 >4HOQ-A nrPDB Length = 482 Score = 33.2 bits (74), Expect = 0.16, Method: Composition-based stats. Identities = 31/167 (18%), Positives = 53/167 (31%), Gaps = 17/167 (10%) Query: 168 SDMTVEE--RIGAADRRKMDGN---SLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQ 222 ++ +E GN + ++LEEA Q+Y I + K + Sbjct: 78 EEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEA-QKYTGKIGNVCKKLSSPSNYKLE 136 Query: 223 DMALAVKNPCHLNIAACLIKLKRYDEAIGHCNIVLTEEEKNPK-------ALFRRGKAKA 275 + C A K Y +A L E NP+ ++R + Sbjct: 137 ----CPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDR 192 Query: 276 ELGQMDSARDDFRKAQKYAPDDKAIRRELRALAEQEKALYQKQKEMY 322 E + RKA PD+ I+ L + A + +K + Sbjct: 193 EGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIE 239 >6FUZ-A nrPDB Length = 337 Score = 33.2 bits (74), Expect = 0.19, Method: Composition-based stats. Identities = 25/143 (17%), Positives = 43/143 (30%), Gaps = 19/143 (13%) Query: 200 QQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAACLIKLKRYDEAIGHCNIVLTE 259 +Y+ A + D + K N+A K +Y EA C L Sbjct: 69 NKYKDAANLLND--ALAIREKTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEI 126 Query: 260 --------EEKNPKALFRRGKAKAELGQMDSARDDFRKAQ-----KYAPDDKAI---RRE 303 K L G+ + +++A K PDD + + Sbjct: 127 REKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALGIYQTKLGPDDPNVAKTKNN 186 Query: 304 LRALAEQEKALYQKQKEMYKGIF 326 L + ++ Q + +YK I Sbjct: 187 LASCYLKQGKFKQAET-LYKEIL 208 >5OJF-A nrPDB Length = 314 Score = 32.0 bits (71), Expect = 0.38, Method: Composition-based stats. Identities = 23/150 (15%), Positives = 41/150 (27%), Gaps = 19/150 (12%) Query: 200 QQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAACLIKLKRYDEAIGHCNIVLT- 258 +Y+ A + D + K N+A K +Y EA C L Sbjct: 84 NKYKDAAHLLND--ALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEI 141 Query: 259 -------EEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYA--------PDDKAIRRE 303 K L G+ + +R+A + P+ + Sbjct: 142 REKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNN 201 Query: 304 LRALAEQEKALYQKQKEMYKGIFKGKDEGG 333 L + ++ + +YK I E Sbjct: 202 LASCYLKQGKYQDAET-LYKEILTRAHEKE 230 >4I9E-A nrPDB Length = 383 Score = 32.0 bits (71), Expect = 0.45, Method: Composition-based stats. Identities = 30/170 (17%), Positives = 57/170 (33%), Gaps = 32/170 (18%) Query: 199 MQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAACLIKLKRYDEAIGHCNIVL- 257 ++QYE AI F + + NI C +Y++AI + + Sbjct: 197 LKQYEDAI----SHFQKAYSMAEAEKQPQLMGRTLYNIGLCKNSQSQYEDAIPYFKRAIA 252 Query: 258 TEEEKN-----PKALFRRGKAKAELGQMDSA-------------------RDDFRKAQKY 293 EE N P+A F + +LG++D A +F + Sbjct: 253 VFEESNILPSLPQAYFLITQIHYKLGKIDKAHEYHSKGMAYSQKAGDVIYLSEFEFLKSL 312 Query: 294 A---PDDKAIRRELRALAEQEKALYQKQKEMYKGIFKGKDEGGAKSKSLF 340 PD++AI+ L + + + + + + K+ + F Sbjct: 313 YLSGPDEEAIQGFFDFLESKMLYADLEDFAIDVAKYYHERKNFQKASAYF 362 Score = 30.5 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 25/126 (19%), Positives = 49/126 (38%), Gaps = 9/126 (7%) Query: 172 VEERIGAADRRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNP 231 E ++ R FK + M+Q ++ Y +++Y +++ + + Sbjct: 129 AESKLIFVKDRIEKAEFFFKMSESYYYMKQTYFSMDY--ARQAYEIYKEHEAYNIRL-LQ 185 Query: 232 CHLNIAACLIKLKRYDEAIGHCNIVLTEEEKNP------KALFRRGKAKAELGQMDSARD 285 CH A + LK+Y++AI H + E + L+ G K Q + A Sbjct: 186 CHSLFATNFLDLKQYEDAISHFQKAYSMAEAEKQPQLMGRTLYNIGLCKNSQSQYEDAIP 245 Query: 286 DFRKAQ 291 F++A Sbjct: 246 YFKRAI 251 >3ZFW-A nrPDB Length = 263 Score = 31.7 bits (70), Expect = 0.61, Method: Composition-based stats. Identities = 23/150 (15%), Positives = 41/150 (27%), Gaps = 19/150 (12%) Query: 200 QQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAACLIKLKRYDEAIGHCNIVLT- 258 +Y+ A + D + K N+A K +Y EA C L Sbjct: 37 NKYKDAAHLLND--ALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEI 94 Query: 259 -------EEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYA--------PDDKAIRRE 303 K L G+ + +R+A + P+ + Sbjct: 95 REKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNN 154 Query: 304 LRALAEQEKALYQKQKEMYKGIFKGKDEGG 333 L + ++ + +YK I E Sbjct: 155 LASCYLKQGKYQDAET-LYKEILTRAHEKE 183 >5C3C-A nrPDB Length = 281 Score = 30.9 bits (68), Expect = 0.89, Method: Composition-based stats. Identities = 15/74 (20%), Positives = 30/74 (40%), Gaps = 7/74 (9%) Query: 237 AACLIKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPD 296 A C + EA +V+ + RR + G++ A DF+ Y P Sbjct: 115 AICYL--DEIVEARQDTIVVIHPLTDH-----RRVLPLEKKGELVEAHPDFQIVISYNPG 167 Query: 297 DKAIRRELRALAEQ 310 +++ ++L+ +Q Sbjct: 168 YQSLMKDLKQSTKQ 181 >1A3W-A nrPDB Length = 500 Score = 30.9 bits (68), Expect = 0.97, Method: Composition-based stats. Identities = 33/265 (12%), Positives = 77/265 (29%), Gaps = 31/265 (11%) Query: 101 KEKKELAGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDE 160 K ++ G + +A G E+ G N +PP ++++ + Sbjct: 69 KSEELYPGRPLAIALDTKG--------PEIRTGTTTNDVDYPIPPNHEMIFTTDDKYAKA 120 Query: 161 TKEGKARSDMTVEERIGAADRR--KMDGNSLFK------EEKLEEAMQQYEMAIAYMGDD 212 + D ++ +A R DG F+ ++ L+ ++ G + Sbjct: 121 CDDKIMYVDYKNITKVISAGRIIYVDDGVLSFQVLEVVDDKTLKVKALNAGKICSHKGVN 180 Query: 213 FMFQLYG---KYQDMALAVKNPCHLNIAACLIKLKRYDEAIGHCNIVLTEEEKNPKALFR 269 + ++ + R + VL E+ K+ K + Sbjct: 181 LPGTDVDLPALSEKDKEDLRFGVKNGVHMVFASFIRTANDVLTIREVLGEQGKDVKIIV- 239 Query: 270 RGKAKAELGQMDSARDDFRKAQKYAPDDKAIRR---ELRALAEQEKALYQK-------QK 319 + + + + D A D I E+ A+ ++ A Sbjct: 240 KIENQQGVNNFDEILKVTDGVM-VARGDLGIEIPAPEVLAVQKKLIAKSNLAGKPVICAT 298 Query: 320 EMYKGIFKGKDEGGAKSKSLFWLIV 344 +M + + A+ + I+ Sbjct: 299 QMLESMTYNPRPTRAEVSDVGNAIL 323 >5O09-1C nrPDB Length = 238 Score = 30.5 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 22/113 (19%), Positives = 48/113 (42%), Gaps = 10/113 (8%) Query: 193 EKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAACLIKLKRYDEAIGH 252 ++++A + YE+A+ ++ + + D +K N+A +L++++ A G+ Sbjct: 89 GRMDKAAEFYELALKISAENGL-----EESDKVATIK----NNLAMIFKQLRKFERAEGY 139 Query: 253 CNIVLT-EEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPDDKAIRREL 304 L + + + R LG + + D +AQ AIR+ L Sbjct: 140 YCEALETFQRLDGEQSARVASVYNNLGVLYYSHMDVDRAQVMHERALAIRQNL 192 >1HXV-A nrPDB Length = 113 Score = 30.5 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 9/66 (13%), Positives = 20/66 (30%), Gaps = 7/66 (10%) Query: 67 YSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIGVASMKSGERAL--V 124 + + N K + EL +G + G G+ +MK ++ + Sbjct: 33 GDIAIIDFTGIVDN--KKLASASAQN--YELTIG-SNSFIKGFETGLIAMKVNQKKTLAL 87 Query: 125 HVGWEL 130 + Sbjct: 88 TFPSDY 93 >5EFR-A nrPDB Length = 446 Score = 30.1 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 25/161 (15%), Positives = 54/161 (33%), Gaps = 16/161 (9%) Query: 188 SLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCH--------LNIAAC 239 + ++ ++ A +YE I D + M +P + I A Sbjct: 246 AYYQNKEYLLAASEYERFIQIYQIDPRVPQAEYERAMCYYKLSPPYELDQTDTRKAIEAF 305 Query: 240 LIKLKRY--DEAIGHCNIVL-TEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPD 296 + + RY E + + K + + + ++A + PD Sbjct: 306 QLFIDRYPNHELVDDATQKIRELRAKLARKQYEAARLYERRELYEAAAVTYEAVFDAYPD 365 Query: 297 ----DKAIRRELRA-LAEQEKALYQKQKEMYKGIFKGKDEG 332 D A+ +RA +A E+++ +Q E Y+ + + Sbjct: 366 TPWADDALVGAMRAYIAYAEQSVRARQPERYRRAVELYERL 406 >2VNC-A nrPDB Length = 718 Score = 30.1 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 14/70 (20%), Positives = 24/70 (34%), Gaps = 7/70 (10%) Query: 95 IELVLGKEKKELAGLAIGVASMKSGERA--LVHVGWELAYGKEGNFSFPNVPPMADLLYE 152 +G + + + SGE V + + E VP ++YE Sbjct: 124 FGYKIGDQNQ-----DLTYDERDSGEYVPKSVVINPYFEWDDEDFIKGKKVPLKDTVIYE 178 Query: 153 VEVIGFDETK 162 V V GF + + Sbjct: 179 VHVKGFTKLR 188 >4CI6-B nrPDB Length = 643 Score = 29.7 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 17/85 (20%), Positives = 34/85 (40%), Gaps = 13/85 (15%) Query: 78 TKNSQHKFEDTWHEQQPIELVLG---KEKKELAGL-------AIGVASMKSGERA-LVHV 126 K F+ +P+ + LG + ++ G +GV ++ + E++ + V Sbjct: 182 IKPGNVVFD--RASGEPVVIDLGLHSRSGEQPKGFTESFKAPELGVGNLGASEKSDVFLV 239 Query: 127 GWELAYGKEGNFSFPNVPPMADLLY 151 L +G EG P + P L + Sbjct: 240 VSTLLHGIEGFEKDPEIKPNQGLRF 264 >1L1F-A nrPDB Length = 505 Score = 29.7 bits (65), Expect = 2.3, Method: Composition-based stats. Identities = 8/37 (21%), Positives = 15/37 (40%) Query: 95 IELVLGKEKKELAGLAIGVASMKSGERALVHVGWELA 131 + L K+ G+ + M +GER + + A Sbjct: 152 FTMELAKKGFIGPGIDVPAPDMSTGEREMSWIADTYA 188 >6OGD-C nrPDB Length = 633 Score = 29.4 bits (64), Expect = 2.5, Method: Composition-based stats. Identities = 19/115 (16%), Positives = 30/115 (26%), Gaps = 25/115 (21%) Query: 59 GHGSKPSKYSTCF--LHYRAWTKNSQHK-------FEDTWHEQQP-------IEL----- 97 G +KP + Y A K F+ Q P Sbjct: 146 GDKTKPKLSAYITDWCQYDARLDGGGSKEEERGRGFDLATLMQNPATYDRLIFSFLGICG 205 Query: 98 VLG----KEKKELAGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMAD 148 +G K ++ G S+ + H+ YG G +PP + Sbjct: 206 DIGNKSKKVQEVWDGWNAQAPSLGLPQIGKGHIVPLDPYGDLGTARNVGLPPESA 260 >4DWS-C nrPDB Length = 546 Score = 29.4 bits (64), Expect = 2.5, Method: Composition-based stats. Identities = 19/115 (16%), Positives = 30/115 (26%), Gaps = 25/115 (21%) Query: 59 GHGSKPSKYSTCF--LHYRAWTKNSQHK-------FEDTWHEQQP-------IEL----- 97 G +KP + Y A K F+ Q P Sbjct: 59 GDKTKPKLSAYITDWCQYDARLDGGGSKEEERGRGFDLATLMQNPATYDRLIFSFLGICG 118 Query: 98 VLG----KEKKELAGLAIGVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMAD 148 +G K ++ G S+ + H+ YG G +PP + Sbjct: 119 DIGNKSKKVQEVWDGWNAQAPSLGLPQIGKGHIVPLDPYGDLGTARNVGLPPESA 173 >6DHM-A nrPDB Length = 582 Score = 29.4 bits (64), Expect = 2.8, Method: Composition-based stats. Identities = 8/37 (21%), Positives = 15/37 (40%) Query: 95 IELVLGKEKKELAGLAIGVASMKSGERALVHVGWELA 131 + L K+ G+ + M +GER + + A Sbjct: 229 FTMELAKKGFIGPGVDVPAPDMSTGEREMSWIADTYA 265 >6AF0-A nrPDB Length = 939 Score = 29.4 bits (64), Expect = 2.8, Method: Composition-based stats. Identities = 16/78 (20%), Positives = 30/78 (38%), Gaps = 11/78 (14%) Query: 245 RYDEAIGHCNIVLTEEEKNPKALFRRGKAKAEL---GQMDSARDDFRKAQK------YAP 295 Y+ A+ + L + KN A +G A A + +A F K ++ Sbjct: 720 AYNRAVEFFDKALQLDPKN--AYAAQGIAIALVEDRKDYKNALQIFIKVRETIQDAHVYV 777 Query: 296 DDKAIRRELRALAEQEKA 313 + I ELR ++ ++ Sbjct: 778 NMGHIYAELRQFSKAIES 795 Score = 27.8 bits (60), Expect = 8.0, Method: Composition-based stats. Identities = 32/169 (18%), Positives = 54/169 (31%), Gaps = 10/169 (5%) Query: 195 LEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNI------AACLIKLKRYDE 248 L+ ++Q A + + QL + A++ N+ A L L RY E Sbjct: 152 LKASLQPSSKAPGAVDSNKAEQLRNALKSFEEAIRVSQGRNMLAVMGKARALFSLGRYPE 211 Query: 249 AIGHCNIVLTEEEKNPKALFRRGKA--KAELGQMDSARDDFRKAQKYAPDDKAIRRELRA 306 ++ V+ + R G +LG D A+ + + + PD K L Sbjct: 212 SLAAYQDVVAKMPDMVDPDPRIGIGCCFWQLGFKDDAKIAWERCLEINPDSKHANILLGL 271 Query: 307 LAEQEKALYQKQKEMYKGIF-KGKDEGGAKSKSLF-WLIVLWQWFVSLF 353 + ++ K E KS L L + F F Sbjct: 272 YYLDASGHVPTNSPEFIRLYKKAMTEYTQKSFKLDKNLPLTCATFAGYF 320 >6D6S-A nrPDB Length = 443 Score = 29.0 bits (63), Expect = 3.5, Method: Composition-based stats. Identities = 36/254 (14%), Positives = 79/254 (31%), Gaps = 16/254 (6%) Query: 68 STCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIGVASMKSGE--RALVH 125 + + +FE + L +G + + + G G+ K+GE V Sbjct: 173 DRVTIDFTGSVD--GEEFEGG--KASDFVLAMG-QGRMIPGFEDGIKGHKAGEEFTIDVT 227 Query: 126 VGWELAYGKEGNFSFPNVPPMADLLYEVEVIGFDET------KEGKARSDMTVEERIGAA 179 E + + + E E+ E + + E R Sbjct: 228 FPEEY-HAENLKGKAAKFAINLKKVEERELPELTAEFIKRFGVEDGSVEGLRAEVRKNME 286 Query: 180 DRRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAAC 239 K + K + +E ++ ++ + D + + L + Sbjct: 287 RELKSAIRNRVKSQAIEGLVKANDIDVPAALIDSEIDVLRRQAAQRFGGNEKQALELPRE 346 Query: 240 LIKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPDDKA 299 L + + + + KA R K E +M SA +D ++ ++ +K Sbjct: 347 LFEEQAKRRVVVGLLLGEVIRTNELKADEERVKGLIE--EMASAYEDPKEVIEFYSKNKE 404 Query: 300 IRRELRALAEQEKA 313 + +R +A +E+A Sbjct: 405 LMDNMRNVALEEQA 418 >3J9W-BF nrPDB Length = 207 Score = 28.6 bits (62), Expect = 4.0, Method: Composition-based stats. Identities = 8/57 (14%), Positives = 21/57 (36%) Query: 137 NFSFPNVPPMADLLYEVEVIGFDETKEGKARSDMTVEERIGAADRRKMDGNSLFKEE 193 N S + P ++++ ++ ++G + E R G + G ++ Sbjct: 20 NASVFGIEPNESVVFDAILMQRASLRQGTHKVKNRSEVRGGGRKPWRQKGTGRARQG 76 >3HTX-A nrPDB Length = 950 Score = 28.6 bits (62), Expect = 4.1, Method: Composition-based stats. Identities = 38/238 (15%), Positives = 72/238 (30%), Gaps = 43/238 (18%) Query: 60 HGSKPSKYSTCFLH----YRAWTKNSQHKFEDTWHEQQPIELVLGKEKKELAGLAIGVAS 115 G P + + Y A ++S E + IE +G + V Sbjct: 584 DGESPREDNESNEEMESEYSANCESSVEPIES----NEEIEFEVGT-GSMNPHIESEVTQ 638 Query: 116 MKSGERALVHVGWE-------LAYGKEGNFSFPNVPPMADLLYEVEVIGFDETKEGKARS 168 M GE A + LA G + + L Y + ++G G + Sbjct: 639 MTVGEYASFKMTPPDAAEALILAVGSDTVRIRSLLSERPCLNYNILLLGVK----GPSEE 694 Query: 169 DMTV--------EERIGAA-DRRKMDGNSLFKE-----EKLEEAMQQYEMAIAYMG---- 210 M ++R+ A + S + L +++ Y ++ + Sbjct: 695 RMEAAFFKPPLSKQRVEYALKHIRESSASTLVDFGCGSGSLLDSLLDYPTSLQTIIGVDI 754 Query: 211 -----DDFMFQLYGKYQDMALAVKNPCHLNIAACLIKLKRYDEAIGHCNIVLTEEEKN 263 L+ K A VK+ + + + +D IG C V+ E++ Sbjct: 755 SPKGLARAAKMLHVKLNKEACNVKSATLYDGSILEFDSRLHDVDIGTCLEVIEHMEED 812 >5FCL-A nrPDB Length = 338 Score = 28.6 bits (62), Expect = 4.3, Method: Composition-based stats. Identities = 14/45 (31%), Positives = 19/45 (42%), Gaps = 3/45 (6%) Query: 243 LKRYDEAIGHC---NIVLTEEEKNPKALFRRGKAKAELGQMDSAR 284 L RY + + C N VL +E KAL+R G A+ Sbjct: 183 LDRYQKGLTDCRTSNDVLVQEAMMTKALYRLAANAVSYGDFTRAK 227 >6EPE-S nrPDB Length = 530 Score = 28.6 bits (62), Expect = 4.5, Method: Composition-based stats. Identities = 15/59 (25%), Positives = 25/59 (42%), Gaps = 4/59 (6%) Query: 246 YDEAIGHCNIVLTEEEKN----PKALFRRGKAKAELGQMDSARDDFRKAQKYAPDDKAI 300 YD+A + + E+ N + L+ G+ KA + AR A + AP A+ Sbjct: 260 YDQAEKLVSKSVFPEQANNNEWARYLYYTGRIKAIQLEYSEARRTMTNALRKAPQHTAV 318 >4G1T-A nrPDB Length = 472 Score = 28.6 bits (62), Expect = 4.9, Method: Composition-based stats. Identities = 12/72 (16%), Positives = 27/72 (37%), Gaps = 2/72 (2%) Query: 255 IVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPDDKAIRRELRAL--AEQEK 312 L + L K + D A + +KA +Y P++ + ++ A+ + Sbjct: 238 EALEKAPGVTDVLRSAAKFYRRKDEPDKAIELLKKALEYIPNNAYLHCQIGCCYRAKVFQ 297 Query: 313 ALYQKQKEMYKG 324 + ++ MY Sbjct: 298 VMNLRENGMYGK 309 >3WPZ-A nrPDB Length = 542 Score = 28.2 bits (61), Expect = 6.1, Method: Composition-based stats. Identities = 10/55 (18%), Positives = 18/55 (32%), Gaps = 2/55 (3%) Query: 98 VLGKEKKELAGLAIG-VASMKSGERALVHVGW-ELAYGKEGNFSFPNVPPMADLL 150 +G + G + M G + +YG EG + ++P L Sbjct: 437 TIGTHDDFVRGGTLAPTVKMDIGVGGDSTKTAVDYSYGSEGLGGWADIPANKHLF 491 >3AHY-A nrPDB Length = 473 Score = 27.8 bits (60), Expect = 7.4, Method: Composition-based stats. Identities = 14/69 (20%), Positives = 23/69 (33%), Gaps = 14/69 (20%) Query: 241 IKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARD----------DFRKA 290 ++K Y+E I + + N K F A + + + A D+ Sbjct: 395 FRVKYYNEYIRAMVTAVELDGVNVKGYF----AWSLMDNFEWADGYVTRFGVTYVDYENG 450 Query: 291 QKYAPDDKA 299 QK P A Sbjct: 451 QKRFPKKSA 459 >3LZX-A nrPDB Length = 332 Score = 27.8 bits (60), Expect = 7.7, Method: Composition-based stats. Identities = 19/69 (27%), Positives = 27/69 (39%), Gaps = 3/69 (4%) Query: 148 DLLYEVEVIGFDETKEGKARSDMTVEERIGAADRRKMDGNSLFKEEKLEEA-MQQYE-MA 205 + E V ++ +G +T EE + GN FK KLE +QYE Sbjct: 83 TICLEQAVESVEKQADG-VFKLVTNEETHYSKTVIITAGNGAFKPRKLELENAEQYEGKN 141 Query: 206 IAYMGDDFM 214 + Y DD Sbjct: 142 LHYFVDDLQ 150 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.126 0.320 Lambda K H 0.267 0.0391 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,509,682 Number of Sequences: 36641 Number of extensions: 470779 Number of successful extensions: 1844 Number of sequences better than 10.0: 125 Number of HSP's better than 10.0 without gapping: 116 Number of HSP's successfully gapped in prelim test: 79 Number of HSP's that attempted gapping in prelim test: 1420 Number of HSP's gapped (non-prelim): 256 length of query: 365 length of database: 10,336,785 effective HSP length: 98 effective length of query: 267 effective length of database: 6,745,967 effective search space: 1801173189 effective search space used: 1801173189 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 60 (27.8 bits)