BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9JIF0 (371 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3Q7E-A nrPDB 711 0.0 5DST-A nrPDB 600 e-172 1G6Q-1 nrPDB 334 3e-92 4RYL-A nrPDB 332 2e-91 6CU3-A nrPDB 325 2e-89 1F3L-A nrPDB 322 1e-88 5JMQ-A nrPDB 218 5e-57 5LV5-A nrPDB 207 8e-54 5EGS-A nrPDB 206 1e-53 3R0Q-C nrPDB 201 4e-52 3B3J-A nrPDB 196 2e-50 4IKP-A nrPDB 196 2e-50 5IS8-A nrPDB 195 2e-50 5FUB-A nrPDB 195 2e-50 4LWO-B nrPDB 143 2e-34 5EKU-A nrPDB 80 2e-15 4M36-A nrPDB 78 5e-15 6OGN-A nrPDB 67 1e-11 3X0D-A nrPDB 56 2e-08 4G56-A nrPDB 41 8e-04 3SVZ-A nrPDB 39 0.004 4LG1-A nrPDB 38 0.009 3LPM-A nrPDB 36 0.020 4FGZ-A nrPDB 36 0.022 3BKW-A nrPDB 35 0.051 3CJR-A nrPDB 34 0.093 3DLC-A nrPDB 34 0.12 3FYD-A nrPDB 33 0.16 2AVN-A nrPDB 33 0.20 3GRV-A nrPDB 33 0.22 5FA5-A nrPDB 32 0.31 1WY7-A nrPDB 32 0.35 5Z9O-A nrPDB 32 0.52 2AS0-A nrPDB 31 0.80 4LZG-A nrPDB 31 1.1 4P7C-A nrPDB 30 1.2 4V7E-BM nrPDB 30 1.5 5FAD-A nrPDB 30 1.7 3QY1-A nrPDB 30 1.8 3I9F-A nrPDB 30 1.9 5JE5-A nrPDB 30 2.0 3DMF-A nrPDB 29 2.6 5CG0-A nrPDB 29 3.7 6AZ1-A nrPDB 28 5.5 4B9C-A nrPDB 28 7.0 4MWZ-A nrPDB 27 9.5 >3Q7E-A nrPDB Length = 349 Score = 711 bits (1836), Expect = 0.0, Method: Compositional matrix adjust. Identities = 339/341 (99%), Positives = 341/341 (100%) Query: 31 VSCGQAESSEKPNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDK 90 +SCGQAESSEKPNAEDMTSKDYYFDSYAHFGIHEE+LKDEVRTLTYRNSMFHNRHLFKDK Sbjct: 9 MSCGQAESSEKPNAEDMTSKDYYFDSYAHFGIHEELLKDEVRTLTYRNSMFHNRHLFKDK 68 Query: 91 VVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVE 150 VVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVE Sbjct: 69 VVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVE 128 Query: 151 LPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRATLYVTAIEDRQYKD 210 LPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRATLYVTAIEDRQYKD Sbjct: 129 LPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRATLYVTAIEDRQYKD 188 Query: 211 YKIHWWENVYGFDMSCIKDVAIKEPLVDVVDPKQLVTNACLIKEVDIYTVKVEDLTFTSP 270 YKIHWWENVYGFDMSCIKDVAIKEPLVDVVDPKQLVTNACLIKEVDIYTVKVEDLTFTSP Sbjct: 189 YKIHWWENVYGFDMSCIKDVAIKEPLVDVVDPKQLVTNACLIKEVDIYTVKVEDLTFTSP 248 Query: 271 FCLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEE 330 FCLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEE Sbjct: 249 FCLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEE 308 Query: 331 IFGTIGMRPNAKNNRDLDFTIDLDFKGQLCELSCSTDYRMR 371 IFGTIGMRPNAKNNRDLDFTIDLDFKGQLCELSCSTDYRMR Sbjct: 309 IFGTIGMRPNAKNNRDLDFTIDLDFKGQLCELSCSTDYRMR 349 >5DST-A nrPDB Length = 332 Score = 600 bits (1547), Expect = e-172, Method: Compositional matrix adjust. Identities = 273/329 (82%), Positives = 308/329 (93%) Query: 43 NAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGIL 102 +E+MTS+DYYFDSYAHFGIHEEMLKDEVRTLTYRNSM+HN+H+FKDKVVLDVGSGTGIL Sbjct: 4 GSEEMTSRDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGTGIL 63 Query: 103 CMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISE 162 MFAAKAGA+KV GIECSSISDY+ KI+KAN LD+++TI KGKVEEVELPVEKVDIIISE Sbjct: 64 SMFAAKAGAKKVFGIECSSISDYSEKIIKANHLDNIITIFKGKVEEVELPVEKVDIIISE 123 Query: 163 WMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGF 222 WMGYCLFYESMLNTV+ ARDKWL P GL+FPDRA LYV AIEDRQYKD+KIHWWENVYGF Sbjct: 124 WMGYCLFYESMLNTVIFARDKWLKPGGLMFPDRAALYVVAIEDRQYKDFKIHWWENVYGF 183 Query: 223 DMSCIKDVAIKEPLVDVVDPKQLVTNACLIKEVDIYTVKVEDLTFTSPFCLQVKRNDYVH 282 DM+CI+DVA+KEPLVD+VDPKQ+VTNACLIKEVDIYTVK E+L+FTS FCLQ++RNDYVH Sbjct: 184 DMTCIRDVAMKEPLVDIVDPKQVVTNACLIKEVDIYTVKTEELSFTSAFCLQIQRNDYVH 243 Query: 283 ALVAYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEEIFGTIGMRPNAK 342 ALV YFNIEFT+CHK+ GFST+P++PYTHWKQTVFY+EDYLTV+ GEEI+GTI M+PNAK Sbjct: 244 ALVTYFNIEFTKCHKKMGFSTAPDAPYTHWKQTVFYLEDYLTVRRGEEIYGTISMKPNAK 303 Query: 343 NNRDLDFTIDLDFKGQLCELSCSTDYRMR 371 N RDLDFT+DLDFKGQLCE S S DY+MR Sbjct: 304 NVRDLDFTVDLDFKGQLCETSVSNDYKMR 332 >1G6Q-1 nrPDB Length = 328 Score = 334 bits (857), Expect = 3e-92, Method: Compositional matrix adjust. Identities = 160/310 (51%), Positives = 218/310 (70%), Gaps = 2/310 (0%) Query: 51 DYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAG 110 DYYFDSY H+GIHEEML+D VRTL+YRN++ N+ LFKDK+VLDVG GTGIL MFAAK G Sbjct: 1 DYYFDSYDHYGIHEEMLQDTVRTLSYRNAIIQNKDLFKDKIVLDVGCGTGILSMFAAKHG 60 Query: 111 ARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFY 170 A+ VIG++ SSI + A ++V+ N +T+++GK+E+V LP KVDIIISEWMGY L Y Sbjct: 61 AKHVIGVDMSSIIEMAKELVELNGFSDKITLLRGKLEDVHLPFPKVDIIISEWMGYFLLY 120 Query: 171 ESMLNTVLHARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDV 230 ESM++TVL+ARD +L GLIFPD+ ++++ +ED QYKD K+++W++VYGFD S + Sbjct: 121 ESMMDTVLYARDHYLVEGGLIFPDKCSIHLAGLEDSQYKDEKLNYWQDVYGFDYSPFVPL 180 Query: 231 AIKEPLVDVVDPKQLVTNACLIKEVDIYTVKVEDLTFTSPFCLQVKRNDYVHALVAYFNI 290 + EP+VD V+ + T + + E D+ TVK+ DL F S F L KR D ++ +V +F+I Sbjct: 181 VLHEPIVDTVERNNVNTTSDKLIEFDLNTVKISDLAFKSNFKLTAKRQDMINGIVTWFDI 240 Query: 291 EF--TRCHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEEIFGTIGMRPNAKNNRDLD 348 F + + FST P +PYTHWKQT+FY D L +TG+ I G + PN KNNRDL+ Sbjct: 241 VFPAPKGKRPVEFSTGPHAPYTHWKQTIFYFPDDLDAETGDTIEGELVCSPNEKNNRDLN 300 Query: 349 FTIDLDFKGQ 358 I F+ Sbjct: 301 IKISYKFESN 310 >4RYL-A nrPDB Length = 340 Score = 332 bits (850), Expect = 2e-91, Method: Compositional matrix adjust. Identities = 159/320 (49%), Positives = 221/320 (69%), Gaps = 3/320 (0%) Query: 42 PNAEDMTSKD--YYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGT 99 P D+ + YF SY H+GIHEEMLKD++RT +YR+ ++ N H+FKDKVVLDVG GT Sbjct: 16 PRGSDLQEDEDGVYFSSYGHYGIHEEMLKDKIRTESYRDFIYQNPHIFKDKVVLDVGCGT 75 Query: 100 GILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDII 159 GIL MFAAKAGA+KV+G++ S I A+ I++ NKL+ +T+IKGK+EEV LPVEKVD+I Sbjct: 76 GILSMFAAKAGAKKVLGVDQSEILYQAMDIIRLNKLEDTITLIKGKIEEVHLPVEKVDVI 135 Query: 160 ISEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENV 219 ISEWMGY L +ESML++VL+A++K+LA G ++PD T+ + A+ D +I +W++V Sbjct: 136 ISEWMGYFLLFESMLDSVLYAKNKYLAKGGSVYPDICTISLVAVSDVNKHADRIAFWDDV 195 Query: 220 YGFDMSCIKDVAIKEPLVDVVDPKQLVTNACLIKEVDIYTVKVEDLTFTSPFCLQVKRND 279 YGF MSC+K I E +V+V+DPK L++ C IK +D +T + DL F+S F L++ R Sbjct: 196 YGFKMSCMKKAVIPEAVVEVLDPKTLISEPCGIKHIDCHTTSISDLEFSSDFTLKITRTS 255 Query: 280 YVHALVAYFNIEFTR-CHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEEIFGTIGMR 338 A+ YF+I F + CH R FST P+S THWKQTVF +E +VK GE + G + + Sbjct: 256 MCTAIAGYFDIYFEKNCHNRVVFSTGPQSTKTHWKQTVFLLEKPFSVKAGEALKGKVTVH 315 Query: 339 PNAKNNRDLDFTIDLDFKGQ 358 N K+ R L T+ L+ Q Sbjct: 316 KNKKDPRSLTVTLTLNNSTQ 335 >6CU3-A nrPDB Length = 336 Score = 325 bits (832), Expect = 2e-89, Method: Compositional matrix adjust. Identities = 167/316 (52%), Positives = 218/316 (68%), Gaps = 8/316 (2%) Query: 61 GIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECS 120 GIHEEMLKD +RT Y+N++ N+HLFKDKVVLD+G GTGILC+FAAKAGA++VIGI+ S Sbjct: 24 GIHEEMLKDGIRTNAYKNAILQNKHLFKDKVVLDIGCGTGILCLFAAKAGAKRVIGIDMS 83 Query: 121 SISDYAVKIVKANKLDHVVTIIKGKVEEV-ELP--VEKVDIIISEWMGYCLFYESMLNTV 177 I D A +IV N HV+ +IKGKVE++ +LP +EKVDIIISEWMGY L YESML TV Sbjct: 84 DIIDKARQIVSDNGYSHVIELIKGKVEDIAQLPFGIEKVDIIISEWMGYFLLYESMLQTV 143 Query: 178 LHARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDVAIKEPLV 237 L ARD+WL P G +FPD+ T+Y+ IED +YK KI +W+NVYGF+ S IK A++EPLV Sbjct: 144 LSARDRWLRPGGYLFPDKCTMYICGIEDSEYKRDKIDFWDNVYGFNFSAIKADALREPLV 203 Query: 238 DVVDPKQLVTNACLIKEVDIYTVKVEDL-TFTSPFCLQVKRNDYVHALVAYFNIEFTRC- 295 D V+ +Q++T E+D+ T++ EDL T+ F + +Y A VA+F+ F+R Sbjct: 204 DFVESQQIITTQSKFLEIDLNTIQPEDLKQITTSFEFTSQYQEYCQAFVAWFDCVFSRGP 263 Query: 296 HKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEEIFGTIGMRPNAKNNRDLDFTIDLDF 355 HK FST P + THWKQTVFY+E+ L +K + I GTI + N N+RDLD ++ Sbjct: 264 HKPVEFSTGPFTEGTHWKQTVFYLENDLPLKPNDVIKGTITISQNKSNHRDLDISMKYTV 323 Query: 356 KGQLCELSCSTDYRMR 371 G S DY MR Sbjct: 324 NGGAV---ISQDYIMR 336 >1F3L-A nrPDB Length = 321 Score = 322 bits (826), Expect = 1e-88, Method: Compositional matrix adjust. Identities = 157/311 (50%), Positives = 214/311 (68%), Gaps = 1/311 (0%) Query: 53 YFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGAR 112 YF SY H+GIHEEMLKD+VRT +YR+ ++ N H+FKDKVVLDVG GTGIL MFAAKAGA+ Sbjct: 10 YFSSYGHYGIHEEMLKDKVRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAK 69 Query: 113 KVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYES 172 KVI ++ S I A+ I++ NKL+ + +IKGK+EEV LPVEKVD+IISEWMGY L +ES Sbjct: 70 KVIAVDQSEILYQAMDIIRLNKLEDTIVLIKGKIEEVSLPVEKVDVIISEWMGYFLLFES 129 Query: 173 MLNTVLHARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDVAI 232 ML++VL+A+ K+LA G ++PD T+ + A+ D +I +W++VYGF+MSC+K I Sbjct: 130 MLDSVLYAKSKYLAKGGSVYPDICTISLVAVSDVSKHADRIAFWDDVYGFNMSCMKKAVI 189 Query: 233 KEPLVDVVDPKQLVTNACLIKEVDIYTVKVEDLTFTSPFCLQVKRNDYVHALVAYFNIEF 292 E +V+VVD K L+++ C IK +D +T + DL F+S F L+ + A+ YF+I F Sbjct: 190 PEAVVEVVDHKTLISDPCDIKHIDCHTTSISDLEFSSDFTLRTTKTAMCTAVAGYFDIYF 249 Query: 293 TR-CHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEEIFGTIGMRPNAKNNRDLDFTI 351 + CH R FST P+S THWKQT+F +E VK GE + G I + N K+ R L T+ Sbjct: 250 EKNCHNRVVFSTGPQSTKTHWKQTIFLLEKPFPVKAGEALKGKITVHKNKKDPRSLIVTL 309 Query: 352 DLDFKGQLCEL 362 L+ Q L Sbjct: 310 TLNSSTQTYSL 320 >5JMQ-A nrPDB Length = 446 Score = 218 bits (554), Expect = 5e-57, Method: Compositional matrix adjust. Identities = 114/322 (35%), Positives = 187/322 (58%), Gaps = 11/322 (3%) Query: 40 EKPNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGT 99 E+ + ED + YFDSY +H EML D+ RT Y + + N+ KDKV+LDVG GT Sbjct: 102 EEYDPEDTWQDEEYFDSYGTLKLHLEMLADQPRTTKYHSVILQNKESLKDKVILDVGCGT 161 Query: 100 GILCMFAAK-AGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDI 158 GI+ +F A A + V +E S ++ + ++V N +T+ + KVE+V LP EKVD+ Sbjct: 162 GIISLFCAHHARPKAVYAVEASDMAQHTSQLVLQNGFADTITVFQQKVEDVVLP-EKVDV 220 Query: 159 IISEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWEN 218 ++SEWMG CL +E M+ ++L+ARD WL DG+I+P A L++ + K+ +W+N Sbjct: 221 LVSEWMGTCLLFEFMIESILYARDTWLKGDGIIWPTTAALHLVPCSAEKDYHSKVLFWDN 280 Query: 219 VYGFDMSCIKDVAIKE----PLVD-VVDPKQLVTNACLIKEVDIYTVKVEDL-TFTSPFC 272 Y F++S +K +AIKE P + ++ P+ ++ C I ++D+ TV+V DL T Sbjct: 281 AYEFNLSALKSLAIKEFFSRPKSNHILKPEDCLSEPCTILQLDMRTVQVPDLETMRGELR 340 Query: 273 LQVKRNDYVHALVAYFNIEFTRCHK---RTGFSTSPESPYTHWKQTVFYMEDYLTVKTGE 329 +++ +H A+F++ F + + ST P P THWKQT+F M+D + V TG+ Sbjct: 341 FDIQKAGTLHGFTAWFSVYFQSLEEGQPQQVLSTGPLHPTTHWKQTLFMMDDPVPVHTGD 400 Query: 330 EIFGTIGMRPNAKNNRDLDFTI 351 + G++ ++ N R + ++ Sbjct: 401 VVTGSVVLQRNPVWRRHMSVSL 422 >5LV5-A nrPDB Length = 403 Score = 207 bits (526), Expect = 8e-54, Method: Compositional matrix adjust. Identities = 115/325 (35%), Positives = 175/325 (53%), Gaps = 16/325 (4%) Query: 41 KPNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTG 100 +P Y++ Y+ +HEEM+ D+VRT YR + N + K VLDVG+GTG Sbjct: 63 RPRRTKSERDQLYYECYSDVSVHEEMIADQVRTEAYRLGILKNWAALRGKTVLDVGAGTG 122 Query: 101 ILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIII 160 IL +F A+AGAR+V +E S+I A ++V+ N L+ V ++ G VE VELP E+VD I+ Sbjct: 123 ILSIFCAQAGARRVYAVEASAIWQQAREVVRLNGLEDRVHVLPGPVETVELP-ERVDAIV 181 Query: 161 SEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENV- 219 SEWMGY L +ESML++VLHAR KWL GL+ P A L+V I D Q ++++ +W V Sbjct: 182 SEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFVAPISD-QMLEWRLGFWSQVK 240 Query: 220 --YGFDMSCIKDVAIK------EPLVDVVDPKQLVTNACLIKEVDIYTVKVE---DLTFT 268 YG DMSC++ A + E +V + + ++ ++++ +E + Sbjct: 241 QHYGVDMSCMESFATRCLMGHSEIVVQDLSGEDVLARPQRFAQLELARAGLEQELEAGVG 300 Query: 269 SPFCLQVKRNDYVHALVAYFNIEFTR--CHKRTGFSTSPESPYTHWKQTVFYMEDYLTVK 326 F + +H +F + F K STSP P THWKQ + Y+ + + V+ Sbjct: 301 GRFRCSCYGSAPLHGFAVWFQVTFPGGDSEKPLVLSTSPLHPATHWKQALLYLNEPVPVE 360 Query: 327 TGEEIFGTIGMRPNAKNNRDLDFTI 351 +I G I + P+ N R L + Sbjct: 361 QDTDISGEITLLPSPDNPRRLRILL 385 >5EGS-A nrPDB Length = 376 Score = 206 bits (524), Expect = 1e-53, Method: Compositional matrix adjust. Identities = 114/322 (35%), Positives = 174/322 (54%), Gaps = 16/322 (4%) Query: 40 EKPNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGT 99 E+P Y++ Y+ +HEEM+ D VRT YR + N + K VLDVG+GT Sbjct: 35 ERPRRTKRERDQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGT 94 Query: 100 GILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDII 159 GIL +F A+AGAR+V +E S+I A ++V+ N L+ V ++ G VE VELP E+VD I Sbjct: 95 GILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELP-EQVDAI 153 Query: 160 ISEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENV 219 +SEWMGY L +ESML++VLHAR KWL GL+ P A L++ I D Q ++++ +W V Sbjct: 154 VSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIVPISD-QMLEWRLGFWSQV 212 Query: 220 ---YGFDMSCIKDVAIK------EPLVDVVDPKQLVTNACLIKEVDIYTVKVE---DLTF 267 YG DMSC++ A + E +V + + ++ ++++ +E + Sbjct: 213 KQHYGVDMSCLEGFATRCLMGHSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQELEAGV 272 Query: 268 TSPFCLQVKRNDYVHALVAYFNIEFT--RCHKRTGFSTSPESPYTHWKQTVFYMEDYLTV 325 F + +H +F + F K STSP P THWKQ + Y+ + + V Sbjct: 273 GGRFRCSCYGSAPMHGFAIWFQVTFPGGESEKPLVLSTSPFHPATHWKQALLYLNEPVQV 332 Query: 326 KTGEEIFGTIGMRPNAKNNRDL 347 + ++ G I + P+ N R L Sbjct: 333 EQDTDVSGEITLLPSRDNPRRL 354 >3R0Q-C nrPDB Length = 376 Score = 201 bits (511), Expect = 4e-52, Method: Compositional matrix adjust. Identities = 110/333 (33%), Positives = 190/333 (57%), Gaps = 30/333 (9%) Query: 53 YFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGAR 112 YF +Y+ ++ML D VR Y N++F N+H F+ K VLDVG+G+GIL +++A+AGAR Sbjct: 28 YFCTYSFLYHQKDMLSDRVRMDAYFNAVFQNKHHFEGKTVLDVGTGSGILAIWSAQAGAR 87 Query: 113 KVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYES 172 KV +E + ++D+A +VKAN LDH+V +I+G VE++ LP EKVD+IISEWMGY L ES Sbjct: 88 KVYAVEATKMADHARALVKANNLDHIVEVIEGSVEDISLP-EKVDVIISEWMGYFLLRES 146 Query: 173 MLNTVLHARDKWLAPDGLIFPDRATLYVTAIE----DRQYKDY--KIHWWENV------- 219 M ++V+ ARD+WL P G+++P A +++ I+ DR+ D+ + W N Sbjct: 147 MFDSVISARDRWLKPTGVMYPSHARMWLAPIKSNIADRKRNDFDGAMADWHNFSDEIKSY 206 Query: 220 YGFDMSCI--------KDVAIKEPLVDVVDPKQLVTNACLIKEVDIYTVKVEDLTFTSPF 271 YG DM + + I+ + + ++P+Q++ ++KE+D T V ++ Sbjct: 207 YGVDMGVLTKPFAEEQEKYYIQTAMWNDLNPQQIIGTPTIVKEMDCLTASVSEIEEVRSN 266 Query: 272 CLQVKRNDYVH--ALVAYFNIEFTR-----CHKRTGFSTSPESPY-THWKQTVFYMEDYL 323 V ++ +F+++F+ + +T+P + THW Q VF M + + Sbjct: 267 VTSVINMEHTRLCGFGGWFDVQFSGRKEDPAQQEIELTTAPSEQHCTHWGQQVFIMSNPI 326 Query: 324 TVKTGEEIFGTIGMRPNAKNNRDLDFTIDLDFK 356 V+ G+ + + M + +N+R ++ ++ + K Sbjct: 327 NVEEGDNLNLGLLMSRSKENHRLMEIELNCEIK 359 >3B3J-A nrPDB Length = 480 Score = 196 bits (497), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 115/326 (35%), Positives = 177/326 (54%), Gaps = 25/326 (7%) Query: 48 TSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAA 107 +S YF Y + + M++D VRT TY+ ++ N FKDK+VLDVG G+GIL FAA Sbjct: 118 SSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAA 177 Query: 108 KAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYC 167 +AGARK+ +E S+++ +A +VK+N L + +I GKVEEV LP E+VDIIISE MGY Sbjct: 178 QAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLP-EQVDIIISEPMGYM 236 Query: 168 LFYESMLNTVLHARDKWLAPDGLIFPDRATLYVTAIEDRQY---KDYKIHWW--ENVYGF 222 LF E ML + LHA+ K+L P G +FP +++ D Q + K ++W + +G Sbjct: 237 LFNERMLESYLHAK-KYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGV 295 Query: 223 DMSCIKDVAI----KEPLVDVVDPKQLVT-------NACLIKEVDIYTVKVEDLTFTSPF 271 D+S ++ A+ ++P+VD D + L+ N KE D++ +++ PF Sbjct: 296 DLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIEI-------PF 348 Query: 272 CLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEEI 331 + + VH L +F++ F ST+P P THW Q + L K G+ + Sbjct: 349 KFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTL 408 Query: 332 FGTIGMRPNAKNNRDLDFTIDLDFKG 357 GT + N + + D+ +D G Sbjct: 409 SGTCLLIANKRQSYDISIVAQVDQTG 434 >4IKP-A nrPDB Length = 341 Score = 196 bits (497), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 114/321 (35%), Positives = 175/321 (54%), Gaps = 25/321 (7%) Query: 53 YFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGAR 112 YF Y + + M++D VRT TY+ ++ N FKDK+VLDVG G+GIL FAA+AGAR Sbjct: 10 YFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGAR 69 Query: 113 KVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYES 172 K+ +E S+++ +A +VK+N L + +I GKVEEV LP E+VDIIISE MGY LF E Sbjct: 70 KIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLP-EQVDIIISEPMGYMLFNER 128 Query: 173 MLNTVLHARDKWLAPDGLIFPDRATLYVTAIEDRQY---KDYKIHWW--ENVYGFDMSCI 227 ML + LHA+ K+L P G +FP +++ D Q + K ++W + +G D+S + Sbjct: 129 MLESYLHAK-KYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSAL 187 Query: 228 KDVAI----KEPLVDVVDPKQLVT-------NACLIKEVDIYTVKVEDLTFTSPFCLQVK 276 + A+ ++P+VD D + L+ N KE D++ +++ PF + Sbjct: 188 RGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIEI-------PFKFHML 240 Query: 277 RNDYVHALVAYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEEIFGTIG 336 + VH L +F++ F ST+P P THW Q + L K G+ + GT Sbjct: 241 HSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTCL 300 Query: 337 MRPNAKNNRDLDFTIDLDFKG 357 + N + + D+ +D G Sbjct: 301 LIANKRQSYDISIVAQVDQTG 321 >5IS8-A nrPDB Length = 381 Score = 195 bits (496), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 114/321 (35%), Positives = 175/321 (54%), Gaps = 25/321 (7%) Query: 53 YFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGAR 112 YF Y + + M++D VRT TY+ ++ N FKDK+VLDVG G+GIL FAA+AGAR Sbjct: 24 YFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGAR 83 Query: 113 KVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYES 172 K+ +E S+++ +A +VK+N L + +I GKVEEV LP E+VDIIISE MGY LF E Sbjct: 84 KIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLP-EQVDIIISEPMGYMLFNER 142 Query: 173 MLNTVLHARDKWLAPDGLIFPDRATLYVTAIEDRQY---KDYKIHWW--ENVYGFDMSCI 227 ML + LHA+ K+L P G +FP +++ D Q + K ++W + +G D+S + Sbjct: 143 MLESYLHAK-KYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSAL 201 Query: 228 KDVAI----KEPLVDVVDPKQLVT-------NACLIKEVDIYTVKVEDLTFTSPFCLQVK 276 + A+ ++P+VD D + L+ N KE D++ +++ PF + Sbjct: 202 RGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIEI-------PFKFHML 254 Query: 277 RNDYVHALVAYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEEIFGTIG 336 + VH L +F++ F ST+P P THW Q + L K G+ + GT Sbjct: 255 HSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTCL 314 Query: 337 MRPNAKNNRDLDFTIDLDFKG 357 + N + + D+ +D G Sbjct: 315 LIANKRQSYDISIVAQVDQTG 335 >5FUB-A nrPDB Length = 337 Score = 195 bits (496), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 112/319 (35%), Positives = 178/319 (55%), Gaps = 17/319 (5%) Query: 46 DMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMF 105 D D YF +Y +H EML D+ RT TYR + N ++KVVLD+G GTG++ +F Sbjct: 2 DAWQDDEYFGNYGTLRLHLEMLSDKPRTETYRQVILSNSAALREKVVLDLGCGTGVISLF 61 Query: 106 AAK-AGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWM 164 A A V +E SS++++ ++VK N D VVT+ + + E + LP KVD+++SEWM Sbjct: 62 CALLAKPAGVYAVEASSMAEHTEELVKQNGCDGVVTVFQERAENLTLPT-KVDVLVSEWM 120 Query: 165 GYCLFYESMLNTVLHARDKWLAPDGLIFPDRATLYVTAIEDRQYKDY--KIHWWENVYGF 222 G CL +E ML +VL ARD+WL G+++P A L T + + + DY K+ +WEN YG Sbjct: 121 GNCLLFEYMLESVLLARDRWLKKGGMMWPSSACL--TIVPCQAFSDYRQKVEFWENPYGL 178 Query: 223 DMSCIKDVAIKEPLVDV-----VDPKQLVTNACLIKEVDIYTVKVEDL-TFTSPFCLQVK 276 + S ++ +A KE L + P+ ++ + +D+ T++V DL F V+ Sbjct: 179 NFSYLQSLAQKEFLSKPKFSHHLQPEDCLSTPADVITLDMVTIQVSDLERLKGEFTFTVE 238 Query: 277 RNDYVHALVAYFNIEFTRCHKRTG----FSTSPESPYTHWKQTVFYMEDYLTVKTGEEIF 332 ++ H +F+ F +C + G +T P S THWKQT+F ++ ++V+ G+ I Sbjct: 239 KSGMFHGFTVWFSAHF-QCLEEDGPSIELNTGPYSEITHWKQTLFMLDAPVSVEEGDIIA 297 Query: 333 GTIGMRPNAKNNRDLDFTI 351 G+I ++ N R L T Sbjct: 298 GSIRLQRNPIWRRHLSITF 316 >4LWO-B nrPDB Length = 368 Score = 143 bits (360), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 104/310 (33%), Positives = 160/310 (51%), Gaps = 46/310 (14%) Query: 53 YFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGAR 112 Y++SY+ +H ML+D R YR S+ + + + KVV+DVGSGTGIL M+AA+AGA+ Sbjct: 20 YYESYSDLAVHRLMLEDAQRMSFYRKSIEQSASI-EGKVVVDVGSGTGILSMWAARAGAK 78 Query: 113 KVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEV--------------ELPVEKVDI 158 V IE SS+S++ + +V+ N L +T++ VE + +L V + Sbjct: 79 HVFSIEASSLSEFQIGVVEDNDLSTKITVLGDTVENIIAGGVANFVNRHKAKLGKCGVAV 138 Query: 159 IISEWMGYCLFYESMLNTVLHARDKW---------LAPDGLIFPDRATLYVTAIEDRQY- 208 ++SEWMG+ LF+E ML +V+ AR+ + L P +I P+RAT++V I + Y Sbjct: 139 LLSEWMGFYLFHEGMLPSVIRARNFFQDVNAALGVLQPIEMI-PERATVFVAPITCKPYY 197 Query: 209 -KDYKIHWWENVYGFDMSCIKDVAIK------EPLVDVVDPKQLVTNACLIKEVDIYTVK 261 + YK ++W +V G D S + + PLV+ + P L+ + E+++ TV+ Sbjct: 198 VQRYK-NFWRDVDGLDFSRYGRIEYEVYLEQASPLVECLPPLCLLHEGLSLIELNLSTVQ 256 Query: 262 VEDLTF---TSPFCLQVKRNDYVHAL---------VAYFNIEFTRCHKRTGFSTSPESPY 309 E LT T F L+ HA V F + F + STSP SP Sbjct: 257 EEVLTSLHNTVHFDLKESAEFQQHAREAGSEGRVSVDGFTVWFDVSYGAHTLSTSPRSPS 316 Query: 310 THWKQTVFYM 319 THWKQT + Sbjct: 317 THWKQTTILL 326 >5EKU-A nrPDB Length = 390 Score = 79.7 bits (195), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 63/242 (26%), Positives = 119/242 (49%), Gaps = 21/242 (8%) Query: 63 HEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECS-S 121 H M+ DE R Y + +H+ + VL++G+G+G+L + AAK GA+ V+ +E S Sbjct: 72 HYAMMNDEERNNFYYEVL--KKHVTPETGVLEIGAGSGLLSLMAAKLGAKWVVAVEGSEE 129 Query: 122 ISDYAVKIVKANKLDHVVTIIKGKVEEVE---LPVEKVDIIISEWMGYCLFYESMLNTVL 178 ++ A + ++AN ++H V ++ E++ LP E D+++SE G + ES L+ V+ Sbjct: 130 LAKLARENIRANNMEHQVKVLHMMSTELKPKHLP-EPPDVLLSEIFGTMMLGESALDYVV 188 Query: 179 HARDKWLAPDGLIFPDRATLYVTAIE-DRQYKDYKIHWWENVYGFDMSCIKDV------- 230 R++ L P I P T Y IE D ++ + W ++ M ++D Sbjct: 189 DVRNRLLKPTTKIIPQFGTQYAVPIECDALHRISSVSGWRDLDLKHMMTLQDTVSIVFAK 248 Query: 231 --AIKEPLVDVVDPKQLVTNACLIKEVDIYTVKVEDLTFTSPFCLQVKRNDYVHALVAYF 288 I+ ++ V+ ++L L + VD + D++ F + K + HA++ Y+ Sbjct: 249 HYGIR---MNSVNFRRLSDPIELFR-VDFSSSNRNDISRRKHFDVVAKESGTAHAMLFYW 304 Query: 289 NI 290 + Sbjct: 305 KV 306 >4M36-A nrPDB Length = 343 Score = 78.2 bits (191), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 69/261 (26%), Positives = 124/261 (47%), Gaps = 31/261 (11%) Query: 63 HEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECS-S 121 H M+ DE R Y + +H+ + VL++G+G+G+L + AAK GA+ V+ +E S Sbjct: 37 HYAMMNDEERNNFYYEVL--KKHVTPETGVLEIGAGSGLLSLMAAKLGAKWVVAVEGSEE 94 Query: 122 ISDYAVKIVKANKLDHVVTIIKGKVEEVE---LPVEKVDIIISEWMGYCLFYESMLNTVL 178 ++ A + ++AN ++H V ++ E++ LP E D+++SE G + ES L+ V+ Sbjct: 95 LAKLARENIRANNMEHQVKVLHMMSTELKSKHLP-EPPDVLLSEIFGTMMLGESALDYVV 153 Query: 179 HARDKWLAPDGLIFPDRATLYVTAIE-DRQYKDYKIHWWENVYGFDMSCIKDV------- 230 R++ L P I P T Y IE D ++ + W ++ M ++D Sbjct: 154 DVRNRLLKPTTKIIPQFGTQYAVPIECDALHRISSVSGWRDLDLKHMMTLQDTVSIVFAK 213 Query: 231 --AIKEPLVDVVDPKQLVTNACLIKEVDIYTVKVEDLTFTSPFCLQVKRNDYVHALVAYF 288 I+ ++ V+ ++L L + VD + D+ F + K + HA++ Y+ Sbjct: 214 HYGIR---MNSVNFRRLSDPIELFR-VDFSSSNRNDIPRRKHFDVVAKESGTAHAMLFYW 269 Query: 289 NI---EFTRCHKRTGFSTSPE 306 + EF ST PE Sbjct: 270 KVTDDEFV-------MSTDPE 283 >6OGN-A nrPDB Length = 692 Score = 67.0 bits (162), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 55/191 (28%), Positives = 90/191 (47%), Gaps = 16/191 (8%) Query: 30 EVSCGQAESSEKPNAEDMTSKDYYFDSYAHFG--IHEEMLKDEVRTLTYRNSMFHNRHLF 87 +V CG+A + + + +D ++D + + +ML D+ R + Y + Sbjct: 2 KVFCGRANPTT--GSLEWLEEDEHYDYHQEIARSSYADMLHDKDRNIKYYQGIRAAVSRV 59 Query: 88 KDK----VVLDVGSGTGILCMFAAKAGARKVIGIEC-SSISDYAVKIVKANKLDHVVTII 142 KD+ +VLD+G+GTG+L M A AGA IE +++ AVKIV+ N + +I Sbjct: 60 KDRGQKALVLDIGTGTGLLSMMAVTAGADFCYAIEVFKPMAEAAVKIVERNGFSDKIKVI 119 Query: 143 KGKVEEV------ELPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRA 196 EV +LP + +I+I+E L E L + HA + D P RA Sbjct: 120 NKHSTEVTVGPDGDLPC-RANILITELFDTELIGEGALPSYEHAHKHLVQEDCEAVPHRA 178 Query: 197 TLYVTAIEDRQ 207 T+Y +E R+ Sbjct: 179 TVYAQLVESRR 189 >3X0D-A nrPDB Length = 655 Score = 56.2 bits (134), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 35/120 (29%), Positives = 58/120 (48%), Gaps = 2/120 (1%) Query: 92 VLDVGSGTGILCMFAAKAGARKVIGIEC-SSISDYAVKIVKANKLDHVVTIIKGKVEEV- 149 VLD+G+GTG+L + AA+ GA KV +E + D A I + +T+I + +V Sbjct: 76 VLDIGTGTGLLSLMAAREGADKVTALEVFKPMGDCARHITSNSPWSDKITVISERSTDVS 135 Query: 150 ELPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRATLYVTAIEDRQYK 209 ++ + DII++E L E L T A ++ P + P +Y+ +E K Sbjct: 136 QIGGSRADIIVAEVFDTELIGEGALRTFKEALERLAKPGCRVVPSTGNVYIVPVESHLLK 195 >4G56-A nrPDB Length = 657 Score = 41.2 bits (95), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 50/191 (26%), Positives = 89/191 (46%), Gaps = 26/191 (13%) Query: 36 AESSEKPNAEDMTSKDY--YFDSYAH-------FGIHEEMLKDEVRTLTYRNSMFH---N 83 +++S PNA +M +K Y Y S +E KD V+ Y+ +++ + Sbjct: 308 SQNSPPPNAYEMFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPVKYSQYQQAVYKCLLD 367 Query: 84 RHLFKDK-----VVLDVGSGTGIL---CMFAAKAGARK--VIGIECSSISDYAVKIVKAN 133 R ++K +++ +G+G G L + AAK RK V +E + + ++ + Sbjct: 368 RVPEEEKETNIQILMVLGAGRGPLVNASLRAAKQAERKIKVYAVEKNPNAVITLEGWRYE 427 Query: 134 KLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNT-VLHARDKWLAPDGLIF 192 + VT++ G + E + P EK DII+SE +G F ++ L+ L +L DG+ Sbjct: 428 EWGSQVTVVSGDMREWKAP-EKADIIVSELLGS--FGDNELSPECLDGAQHFLKDDGVSI 484 Query: 193 PDRATLYVTAI 203 P T Y+ I Sbjct: 485 PGEYTSYLAPI 495 >3SVZ-A nrPDB Length = 263 Score = 38.9 bits (89), Expect = 0.004, Method: Compositional matrix adjust. Identities = 33/118 (27%), Positives = 53/118 (44%), Gaps = 7/118 (5%) Query: 86 LFKDKVVLDVGSGTGILCMFAAKAGARKVIGIEC--SSISDYAVKIVKANKLDHVVTIIK 143 L D + D+G GTG +F A ++ GI+ I + VKAN D V I Sbjct: 50 LTDDAKIADIGCGTGGQTLFLADYVKGQITGIDLFPDFIEIFNENAVKANCADRVKGIT- 108 Query: 144 GKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRATLYVT 201 G ++ + E++D+I SE Y + +E +N K+L G I A+ + + Sbjct: 109 GSMDNLPFQNEELDLIWSEGAIYNIGFERGMNEW----SKYLKKGGFIAVSEASWFTS 162 >4LG1-A nrPDB Length = 224 Score = 37.7 bits (86), Expect = 0.009, Method: Compositional matrix adjust. Identities = 32/99 (32%), Positives = 49/99 (49%), Gaps = 11/99 (11%) Query: 85 HLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVT-IIK 143 H + VL++GSGTG + + AA GA V+ + + D + NK H+VT ++ Sbjct: 59 HALSRRSVLELGSGTGAVGLMAATLGADVVV-TDLEELQDLLKMNINMNK--HLVTGSVQ 115 Query: 144 GKV----EEVELPVEKVDIIISEWMGYCLFYESMLNTVL 178 KV EE+E D I+ M C++YE L +L Sbjct: 116 AKVLKWGEEIEGFPSPPDFIL---MADCIYYEESLEPLL 151 >3LPM-A nrPDB Length = 259 Score = 36.2 bits (82), Expect = 0.020, Method: Compositional matrix adjust. Identities = 24/93 (25%), Positives = 49/93 (52%), Gaps = 3/93 (3%) Query: 92 VLDVGSGTGILCMFAAKAGARKVIGIECSS-ISDYAVKIVKANKLDHVVTIIKGKVEEVE 150 ++D+ SG GI+ + + K++G+E ++D A + V N+L+ + II+ ++++ Sbjct: 53 IIDLCSGNGIIPLLLSTRTKAKIVGVEIQERLADMAKRSVAYNQLEDQIEIIEYDLKKIT 112 Query: 151 --LPVEKVDIIISEWMGYCLFYESMLNTVLHAR 181 +P E+ DI+ + S+ NT H R Sbjct: 113 DLIPKERADIVTCNPPYFATPDTSLKNTNEHFR 145 >4FGZ-A nrPDB Length = 266 Score = 36.2 bits (82), Expect = 0.022, Method: Compositional matrix adjust. Identities = 31/108 (28%), Positives = 47/108 (43%), Gaps = 5/108 (4%) Query: 86 LFKDKVVLDVGSGTGILCMFAAKAGARKVIGIE-CSSISDYAVKIVKANKLDHVVTIIKG 144 L ++ VLD+GSG G CM+ + GI+ CS+I + A + V N + + Sbjct: 53 LNENSKVLDIGSGLGGGCMYINEKYGAHTHGIDICSNIVNMANERVSGN---NKIIFEAN 109 Query: 145 KVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIF 192 + E P D+I S L E+ N + KWL P G + Sbjct: 110 DILTKEFPENNFDLIYSRDAILHLSLENK-NKLFQKCYKWLKPTGTLL 156 >3BKW-A nrPDB Length = 243 Score = 35.0 bits (79), Expect = 0.051, Method: Compositional matrix adjust. Identities = 25/111 (22%), Positives = 52/111 (46%), Gaps = 7/111 (6%) Query: 92 VLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVEL 151 ++D+G G G C +A + GA V+G++ +S+ + +A D +T + ++++ L Sbjct: 47 IVDLGCGFGWFCRWAHEHGASYVLGLD---LSEKMLARARAAGPDTGITYERADLDKLHL 103 Query: 152 PVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDG-LIFPDRATLYVT 201 P + D+ S L Y + + + L+P G +F +Y+ Sbjct: 104 PQDSFDLAYSS---LALHYVEDVARLFRTVHQALSPGGHFVFSTEHPIYMA 151 >3CJR-A nrPDB Length = 254 Score = 34.3 bits (77), Expect = 0.093, Method: Compositional matrix adjust. Identities = 24/80 (30%), Positives = 42/80 (52%), Gaps = 7/80 (8%) Query: 84 RHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVV--TI 141 RHL VLD+G+G+G+L + A K G K +G++ I + +AN + V Sbjct: 116 RHLRPGDKVLDLGTGSGVLAIAAEKLGG-KALGVD---IDPMVLPQAEANAKRNGVRPRF 171 Query: 142 IKGKVEEVELPVEKVDIIIS 161 ++G + E LP D++++ Sbjct: 172 LEGSL-EAALPFGPFDLLVA 190 >3DLC-A nrPDB Length = 219 Score = 33.9 bits (76), Expect = 0.12, Method: Compositional matrix adjust. Identities = 23/92 (25%), Positives = 44/92 (47%), Gaps = 3/92 (3%) Query: 83 NRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSS-ISDYAVKIVKANKLDHVVTI 141 NR +D+GSG G L + AK + ++ S +++ A+K + L+ + I Sbjct: 38 NRFGITAGTCIDIGSGPGALSIALAKQSDFSIRALDFSKHMNEIALKNIADANLNDRIQI 97 Query: 142 IKGKVEEVELPVEKVDIIISEWMGYCLFYESM 173 ++G V + + D+I+S G F+E + Sbjct: 98 VQGDVHNIPIEDNYADLIVSR--GSVFFWEDV 127 >3FYD-A nrPDB Length = 263 Score = 33.5 bits (75), Expect = 0.16, Method: Compositional matrix adjust. Identities = 29/78 (37%), Positives = 42/78 (53%), Gaps = 5/78 (6%) Query: 75 TYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIEC-SSISDYAVKIVKAN 133 + N + +L KD VVL++G G GIL AK A+KV IE S+ YA K+ Sbjct: 8 NFVNKAVESANLTKDDVVLEIGLGKGILTEELAK-NAKKVYVIEIDKSLEPYANKL---K 63 Query: 134 KLDHVVTIIKGKVEEVEL 151 +L + + II G +V+L Sbjct: 64 ELYNNIEIIWGDALKVDL 81 >2AVN-A nrPDB Length = 260 Score = 33.1 bits (74), Expect = 0.20, Method: Compositional matrix adjust. Identities = 23/100 (23%), Positives = 46/100 (46%), Gaps = 9/100 (9%) Query: 92 VLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVEL 151 VLD+G GTG +F + G V + D + ++++ + V +++ K E++ Sbjct: 58 VLDLGGGTGKWSLFLQERGFEVV-------LVDPSKEMLEVAREKGVKNVVEAKAEDLPF 110 Query: 152 PVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLI 191 P + +++ +G L Y + + L PDGL+ Sbjct: 111 PSGAFEAVLA--LGDVLSYVENKDKAFSEIRRVLVPDGLL 148 >3GRV-A nrPDB Length = 295 Score = 33.1 bits (74), Expect = 0.22, Method: Compositional matrix adjust. Identities = 29/78 (37%), Positives = 42/78 (53%), Gaps = 5/78 (6%) Query: 75 TYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIEC-SSISDYAVKIVKAN 133 + N + +L KD VVL++G G GIL AK A+KV IE S+ YA K+ Sbjct: 37 NFVNKAVESANLTKDDVVLEIGLGKGILTEELAK-NAKKVYVIEIDKSLEPYANKL---K 92 Query: 134 KLDHVVTIIKGKVEEVEL 151 +L + + II G +V+L Sbjct: 93 ELYNNIEIIWGDALKVDL 110 >5FA5-A nrPDB Length = 650 Score = 32.3 bits (72), Expect = 0.31, Method: Compositional matrix adjust. Identities = 32/120 (26%), Positives = 58/120 (48%), Gaps = 9/120 (7%) Query: 90 KVVLDVGSGTGIL---CMFAAKAGAR--KVIGIECSSISDYAVKIVKANKLDHVVTIIKG 144 +V++ +G+G G L + AAK R K+ +E + + ++ + + VT++ Sbjct: 372 QVLMVLGAGRGPLVNASLRAAKQADRRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSS 431 Query: 145 KVEEVELPVEKVDIIISEWMGYCLFYESMLNT-VLHARDKWLAPDGLIFPDRATLYVTAI 203 + E P EK DII+SE +G F ++ L+ L +L DG+ P T ++ I Sbjct: 432 DMREWVAP-EKADIIVSELLGS--FADNELSPECLDGAQHFLKDDGVSIPGEYTSFLAPI 488 >1WY7-A nrPDB Length = 207 Score = 32.3 bits (72), Expect = 0.35, Method: Compositional matrix adjust. Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 8/73 (10%) Query: 90 KVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKAN--KLDHVVTIIKGKVE 147 KVV D+G+GTG+L A GA++VI C + AV ++ N + + G V Sbjct: 51 KVVADLGAGTGVLSYGALLLGAKEVI---CVEVDKEAVDVLIENLGEFKGKFKVFIGDVS 107 Query: 148 EVELPVEKVDIII 160 E +VDI+I Sbjct: 108 EFN---SRVDIVI 117 >5Z9O-A nrPDB Length = 399 Score = 31.6 bits (70), Expect = 0.52, Method: Compositional matrix adjust. Identities = 19/57 (33%), Positives = 30/57 (52%), Gaps = 3/57 (5%) Query: 80 MFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLD 136 + + H K K +LD+G G G L + AAK KV G+ ++S+ K+V+ D Sbjct: 157 ILNKLHPEKGKTLLDIGCGWGTLMLTAAKEYGLKVTGV---TLSEEQYKLVQKKIYD 210 >2AS0-A nrPDB Length = 396 Score = 31.2 bits (69), Expect = 0.80, Method: Compositional matrix adjust. Identities = 26/74 (35%), Positives = 43/74 (58%), Gaps = 5/74 (6%) Query: 92 VLDVGSGTGILCMFAAKAGARKVIGIECSSIS-DYAVKIVKANKLDHVVTIIKG----KV 146 VLDV + TG + AA AGA +VIGI+ S + + A + K N ++ + I G ++ Sbjct: 221 VLDVFTYTGGFAIHAAIAGADEVIGIDKSPRAIETAKENAKLNGVEDRMKFIVGSAFEEM 280 Query: 147 EEVELPVEKVDIII 160 E+++ EK DI++ Sbjct: 281 EKLQKKGEKFDIVV 294 >4LZG-A nrPDB Length = 356 Score = 30.8 bits (68), Expect = 1.1, Method: Compositional matrix adjust. Identities = 16/61 (26%), Positives = 26/61 (42%) Query: 145 KVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRATLYVTAIE 204 +V+ V PV + + W G LF + + WL GL P++ T + A E Sbjct: 278 RVDLVVAPVSQFPFALLGWTGSKLFQRELRRFSRKEKGLWLNSHGLFDPEQKTFFQAASE 337 Query: 205 D 205 + Sbjct: 338 E 338 >4P7C-A nrPDB Length = 322 Score = 30.4 bits (67), Expect = 1.2, Method: Compositional matrix adjust. Identities = 31/123 (25%), Positives = 54/123 (43%), Gaps = 6/123 (4%) Query: 60 FGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIEC 119 FG+H + E R+ ++ S K K VLDVG G G AGA VIG++ Sbjct: 97 FGVH---IDTEWRS-DWKWSRVSPHLDLKGKRVLDVGCGNGYYQWRMLGAGADSVIGVDP 152 Query: 120 SSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLH 179 + + + ++ D + +E++ +E D + S MG +S ++ +L Sbjct: 153 NWLFFCQFQAMQRYLPDLPAWHLPFALEDLPANLEGFDTVFS--MGVLYHRKSPIDHLLA 210 Query: 180 ARD 182 +D Sbjct: 211 LKD 213 >4V7E-BM nrPDB Length = 171 Score = 30.0 bits (66), Expect = 1.5, Method: Compositional matrix adjust. Identities = 16/45 (35%), Positives = 21/45 (46%), Gaps = 1/45 (2%) Query: 82 HNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYA 126 HN HL +G G LC ++ ARKV+G C + DY Sbjct: 112 HNVHLVTVPSAKTLGEWAG-LCKIDSEGKARKVVGCSCVVVKDYG 155 >5FAD-A nrPDB Length = 161 Score = 30.0 bits (66), Expect = 1.7, Method: Compositional matrix adjust. Identities = 32/106 (30%), Positives = 52/106 (49%), Gaps = 18/106 (16%) Query: 88 KDKVVLDVGSGTGILCMFAAKA-GARKVIGIECSSISDYAVKIVKANKLDHVVT----II 142 +D +V D+G G G + + AAK +K +G+E I+D ++ AN + VT I+ Sbjct: 28 QDDIVYDLGCGDGRIIITAAKDFNVKKAVGVE---INDERIREALANIEKNGVTGRASIV 84 Query: 143 KGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLHAR-DKWLAP 187 KG EV+ ISE +F + +N +L + +K L P Sbjct: 85 KGNFFEVD---------ISEATVVTMFLLTNVNEMLKPKLEKELKP 121 >3QY1-A nrPDB Length = 223 Score = 30.0 bits (66), Expect = 1.8, Method: Compositional matrix adjust. Identities = 33/152 (21%), Positives = 60/152 (39%), Gaps = 28/152 (18%) Query: 117 IECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDI-IISEWMGYCLFYESMLN 175 + C S+ YAV +++ ++H++ ++ VE ++ +I+ W+ Sbjct: 78 LNCLSVVQYAVDVLE---VEHIIICGHSGCGGIKAAVENPELGLINNWL----------- 123 Query: 176 TVLHARDKWLAPDGLI--FPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDVAIK 233 LH RD WL L+ P+ E R Y+++ E VY S I A K Sbjct: 124 --LHIRDIWLKHSSLLGKMPE---------EQRLDALYELNVMEQVYNLGHSTIMQSAWK 172 Query: 234 EPLVDVVDPKQLVTNACLIKEVDIYTVKVEDL 265 + N L++++D+ E L Sbjct: 173 RGQNVTIHGWAYSINDGLLRDLDVTATNRETL 204 >3I9F-A nrPDB Length = 170 Score = 29.6 bits (65), Expect = 1.9, Method: Compositional matrix adjust. Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 9/73 (12%) Query: 88 KDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVE 147 K V++D G G G C + + + + C I+ A+K VK K D V+T+ K Sbjct: 17 KKGVIVDYGCGNGFYCKYLLEFATK----LYCIDINVIALKEVKE-KFDSVITLSDPK-- 69 Query: 148 EVELPVEKVDIII 160 E+P VD I+ Sbjct: 70 --EIPDNSVDFIL 80 >5JE5-A nrPDB Length = 247 Score = 29.6 bits (65), Expect = 2.0, Method: Compositional matrix adjust. Identities = 23/106 (21%), Positives = 48/106 (45%), Gaps = 6/106 (5%) Query: 61 GIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECS 120 G+ E+ + + ++FH K VLD+ G G + GA KV+G++ Sbjct: 14 GLFEDFTQSAAQRAIEVRTIFHMIGDVSGKSVLDLACGFGFFGREIYRRGAAKVVGVD-- 71 Query: 121 SISDYAVKIVK--ANKLDHVVTIIKGKVEEVELPVEKVDIIISEWM 164 IS+ +++ + + K + V +E P+ + D++ + W+ Sbjct: 72 -ISEKMIELAREESRKYGDPLEFHVRDVANME-PLGQFDLVNAAWL 115 >3DMF-A nrPDB Length = 381 Score = 29.3 bits (64), Expect = 2.6, Method: Compositional matrix adjust. Identities = 23/75 (30%), Positives = 41/75 (54%), Gaps = 4/75 (5%) Query: 88 KDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAV-KIVKANKLDHVVTIIKGKV 146 + + VLD+G+G G L + A+ GA +V+G+E S ++ K ++AN L + V Sbjct: 233 RGRQVLDLGAGYGALTLPLARMGA-EVVGVEDDLASVLSLQKGLEANALK--AQALHSDV 289 Query: 147 EEVELPVEKVDIIIS 161 +E + DII++ Sbjct: 290 DEALTEEARFDIIVT 304 >5CG0-A nrPDB Length = 489 Score = 28.9 bits (63), Expect = 3.7, Method: Compositional matrix adjust. Identities = 13/33 (39%), Positives = 19/33 (57%) Query: 60 FGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVV 92 FG++E D RT T R + F +H+ K +VV Sbjct: 440 FGLYEVDFSDPARTRTPRKAAFVYKHIIKHRVV 472 >6AZ1-A nrPDB Length = 264 Score = 28.5 bits (62), Expect = 5.5, Method: Compositional matrix adjust. Identities = 16/48 (33%), Positives = 24/48 (50%), Gaps = 1/48 (2%) Query: 252 IKEVDIYTVKVEDLTFTSPFCLQVKRNDYV-HALVAYFNIEFTRCHKR 298 +K D YT+++ + FT P Q RN Y LV + + T+ KR Sbjct: 130 VKTADGYTMRLFVVAFTKPQANQQSRNCYAKQRLVKWLRMRITKMIKR 177 >4B9C-A nrPDB Length = 150 Score = 28.1 bits (61), Expect = 7.0, Method: Compositional matrix adjust. Identities = 11/46 (23%), Positives = 25/46 (54%) Query: 278 NDYVHALVAYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYMEDYL 323 ND ++ ++ ++T+ +R +S +P Y+ WK+ Y+ + L Sbjct: 99 NDVMYITGEFYKNDWTKFEQRDDYSYNPADSYSDWKRMTAYISNKL 144 >4MWZ-A nrPDB Length = 267 Score = 27.3 bits (59), Expect = 9.5, Method: Compositional matrix adjust. Identities = 27/102 (26%), Positives = 42/102 (41%), Gaps = 5/102 (4%) Query: 92 VLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGK-VEEVE 150 VLD+GSG G C + + V G++ I + V I K D + K + + + Sbjct: 59 VLDIGSGLGGGCKYINEKYGAHVHGVD---ICEKMVTIAKLRNQDKAKIEFEAKDILKKD 115 Query: 151 LPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIF 192 P D+I S L Y + KWL P+G++ Sbjct: 116 FPESTFDMIYSRDSILHLSYADK-KMLFEKCYKWLKPNGILL 156 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3Q7E-A nrPDB 530 e-151 5DST-A nrPDB 491 e-139 4RYL-A nrPDB 434 e-122 1F3L-A nrPDB 428 e-120 1G6Q-1 nrPDB 419 e-118 6CU3-A nrPDB 412 e-115 5JMQ-A nrPDB 391 e-109 5LV5-A nrPDB 389 e-108 5EGS-A nrPDB 388 e-108 5FUB-A nrPDB 375 e-104 3B3J-A nrPDB 347 3e-96 4IKP-A nrPDB 346 1e-95 5IS8-A nrPDB 344 3e-95 3R0Q-C nrPDB 337 4e-93 4LWO-B nrPDB 278 3e-75 5EKU-A nrPDB 242 2e-64 4M36-A nrPDB 242 2e-64 6OGN-A nrPDB 205 3e-53 4G56-A nrPDB 179 2e-45 3X0D-A nrPDB 165 3e-41 Sequences not found previously or not previously below threshold: 5FA5-A nrPDB 161 5e-40 3UA4-A nrPDB 78 5e-15 2AS0-A nrPDB 55 6e-08 5Z9O-A nrPDB 50 1e-06 3DLC-A nrPDB 49 3e-06 1L3B-A nrPDB 49 3e-06 3SVZ-A nrPDB 48 6e-06 1WY7-A nrPDB 48 8e-06 3LPM-A nrPDB 47 2e-05 2ZZN-A nrPDB 45 5e-05 5WP5-A nrPDB 45 7e-05 3CJR-A nrPDB 44 1e-04 3A26-A nrPDB 44 1e-04 4LG1-A nrPDB 44 1e-04 5WP4-A nrPDB 42 3e-04 4P7C-A nrPDB 42 3e-04 3A27-A nrPDB 42 5e-04 5JE5-A nrPDB 42 5e-04 3EGE-A nrPDB 41 6e-04 3D2L-A nrPDB 40 0.002 3BKW-A nrPDB 40 0.002 2YXD-A nrPDB 39 0.003 5YAC-A nrPDB 39 0.003 4PNE-A nrPDB 39 0.003 4KDR-A nrPDB 39 0.003 4KDC-A nrPDB 39 0.003 4QNV-A nrPDB 39 0.003 2AVN-A nrPDB 39 0.004 4FS8-A nrPDB 39 0.005 5FAD-A nrPDB 39 0.005 1VQ1-A nrPDB 38 0.006 2PJD-A nrPDB 38 0.007 1XDU-A nrPDB 38 0.007 3DMF-A nrPDB 38 0.008 1I9G-A nrPDB 38 0.008 3ELU-A nrPDB 38 0.008 4HGY-A nrPDB 38 0.009 4KRG-A nrPDB 37 0.010 1DUS-A nrPDB 37 0.010 3CCF-A nrPDB 37 0.012 3MGG-A nrPDB 37 0.014 6BQC-A nrPDB 37 0.014 1KP9-A nrPDB 37 0.014 5GM1-A nrPDB 37 0.015 2P8J-A nrPDB 37 0.016 5BP9-A nrPDB 37 0.016 3GRV-A nrPDB 37 0.017 3FYD-A nrPDB 37 0.017 4O29-A nrPDB 36 0.020 4IV8-A nrPDB 36 0.025 1ZQ9-A nrPDB 35 0.050 1RI1-A nrPDB 35 0.058 5I2H-A nrPDB 35 0.059 6GKZ-A nrPDB 35 0.059 5ZW4-A nrPDB 35 0.065 3LGA-A nrPDB 35 0.065 4MWZ-A nrPDB 35 0.067 1XCL-A nrPDB 34 0.095 2OXT-A nrPDB 34 0.10 2VS1-A nrPDB 34 0.12 4FGZ-A nrPDB 34 0.13 4QPN-A nrPDB 34 0.15 5BXY-A nrPDB 34 0.15 3HEM-A nrPDB 34 0.17 3BKX-A nrPDB 33 0.21 2YR0-A nrPDB 33 0.21 2YVL-A nrPDB 33 0.23 5U19-A nrPDB 33 0.23 3BUS-A nrPDB 33 0.27 5BP7-A nrPDB 33 0.29 5H02-A nrPDB 32 0.30 4HTF-A nrPDB 32 0.30 6MRO-A nrPDB 32 0.34 5IKM-A nrPDB 32 0.39 2I6G-A nrPDB 32 0.43 1UWV-A nrPDB 32 0.49 5EHG-A nrPDB 32 0.50 3NDI-A nrPDB 32 0.53 6DCC-A nrPDB 32 0.58 6C5B-A nrPDB 32 0.58 6GFK-A nrPDB 32 0.63 6DU5-A nrPDB 32 0.63 1ECF-A nrPDB 32 0.64 4QDJ-A nrPDB 31 0.68 3NJR-A nrPDB 31 0.68 4LEC-A nrPDB 31 0.74 4V0R-A nrPDB 31 0.75 2B25-A nrPDB 31 0.88 6AW7-A nrPDB 31 0.90 2GLU-A nrPDB 31 0.94 1R74-A nrPDB 31 0.94 1D2C-A nrPDB 31 0.94 2VN8-A nrPDB 31 0.95 1KR5-A nrPDB 31 1.0 2AJB-A nrPDB 30 1.1 1YUB-A nrPDB 30 1.1 1O54-A nrPDB 30 1.3 1P1B-A nrPDB 30 1.3 3P9N-A nrPDB 30 1.4 3SM3-A nrPDB 30 1.5 2XVM-A nrPDB 30 1.5 6M83-A nrPDB 30 1.6 3C3P-A nrPDB 30 1.7 4NEC-A nrPDB 30 1.8 6H1E-A nrPDB 30 1.8 1NKV-A nrPDB 30 2.1 4F5V-A nrPDB 30 2.2 5EVJ-A nrPDB 30 2.2 1DL5-A nrPDB 30 2.2 3HP7-A nrPDB 29 2.5 3GCZ-A nrPDB 29 2.8 2O5R-A nrPDB 29 3.1 2B3T-A nrPDB 29 3.3 4AZW-A nrPDB 29 3.5 2GS9-A nrPDB 29 3.6 4OIC-B nrPDB 29 3.6 3OPN-A nrPDB 29 3.7 5X4Z-H nrPDB 29 3.8 1DOH-A nrPDB 29 3.8 4AZV-A nrPDB 29 4.1 2H1R-A nrPDB 29 4.1 4OA5-A nrPDB 29 4.3 3L8D-A nrPDB 29 4.4 5IKP-A nrPDB 29 4.5 3TM5-A nrPDB 29 4.9 5IJO-H nrPDB 29 5.0 3EVC-A nrPDB 29 5.1 4DCM-A nrPDB 29 5.4 4G1P-A nrPDB 28 5.5 5KPG-A nrPDB 28 5.6 4MTL-A nrPDB 28 5.6 3VC2-A nrPDB 28 5.6 3G7U-A nrPDB 28 5.7 1MD6-A nrPDB 28 5.9 2FHP-A nrPDB 28 6.4 2QT9-A nrPDB 28 6.6 6IFX-A nrPDB 28 8.8 6IFV-A nrPDB 28 8.8 >3Q7E-A nrPDB Length = 349 Score = 530 bits (1364), Expect = e-151, Method: Composition-based stats. Identities = 339/341 (99%), Positives = 341/341 (100%) Query: 31 VSCGQAESSEKPNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDK 90 +SCGQAESSEKPNAEDMTSKDYYFDSYAHFGIHEE+LKDEVRTLTYRNSMFHNRHLFKDK Sbjct: 9 MSCGQAESSEKPNAEDMTSKDYYFDSYAHFGIHEELLKDEVRTLTYRNSMFHNRHLFKDK 68 Query: 91 VVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVE 150 VVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVE Sbjct: 69 VVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVE 128 Query: 151 LPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRATLYVTAIEDRQYKD 210 LPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRATLYVTAIEDRQYKD Sbjct: 129 LPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRATLYVTAIEDRQYKD 188 Query: 211 YKIHWWENVYGFDMSCIKDVAIKEPLVDVVDPKQLVTNACLIKEVDIYTVKVEDLTFTSP 270 YKIHWWENVYGFDMSCIKDVAIKEPLVDVVDPKQLVTNACLIKEVDIYTVKVEDLTFTSP Sbjct: 189 YKIHWWENVYGFDMSCIKDVAIKEPLVDVVDPKQLVTNACLIKEVDIYTVKVEDLTFTSP 248 Query: 271 FCLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEE 330 FCLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEE Sbjct: 249 FCLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEE 308 Query: 331 IFGTIGMRPNAKNNRDLDFTIDLDFKGQLCELSCSTDYRMR 371 IFGTIGMRPNAKNNRDLDFTIDLDFKGQLCELSCSTDYRMR Sbjct: 309 IFGTIGMRPNAKNNRDLDFTIDLDFKGQLCELSCSTDYRMR 349 >5DST-A nrPDB Length = 332 Score = 491 bits (1264), Expect = e-139, Method: Composition-based stats. Identities = 273/331 (82%), Positives = 308/331 (93%) Query: 41 KPNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTG 100 +E+MTS+DYYFDSYAHFGIHEEMLKDEVRTLTYRNSM+HN+H+FKDKVVLDVGSGTG Sbjct: 2 PLGSEEMTSRDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGTG 61 Query: 101 ILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIII 160 IL MFAAKAGA+KV GIECSSISDY+ KI+KAN LD+++TI KGKVEEVELPVEKVDIII Sbjct: 62 ILSMFAAKAGAKKVFGIECSSISDYSEKIIKANHLDNIITIFKGKVEEVELPVEKVDIII 121 Query: 161 SEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVY 220 SEWMGYCLFYESMLNTV+ ARDKWL P GL+FPDRA LYV AIEDRQYKD+KIHWWENVY Sbjct: 122 SEWMGYCLFYESMLNTVIFARDKWLKPGGLMFPDRAALYVVAIEDRQYKDFKIHWWENVY 181 Query: 221 GFDMSCIKDVAIKEPLVDVVDPKQLVTNACLIKEVDIYTVKVEDLTFTSPFCLQVKRNDY 280 GFDM+CI+DVA+KEPLVD+VDPKQ+VTNACLIKEVDIYTVK E+L+FTS FCLQ++RNDY Sbjct: 182 GFDMTCIRDVAMKEPLVDIVDPKQVVTNACLIKEVDIYTVKTEELSFTSAFCLQIQRNDY 241 Query: 281 VHALVAYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEEIFGTIGMRPN 340 VHALV YFNIEFT+CHK+ GFST+P++PYTHWKQTVFY+EDYLTV+ GEEI+GTI M+PN Sbjct: 242 VHALVTYFNIEFTKCHKKMGFSTAPDAPYTHWKQTVFYLEDYLTVRRGEEIYGTISMKPN 301 Query: 341 AKNNRDLDFTIDLDFKGQLCELSCSTDYRMR 371 AKN RDLDFT+DLDFKGQLCE S S DY+MR Sbjct: 302 AKNVRDLDFTVDLDFKGQLCETSVSNDYKMR 332 >4RYL-A nrPDB Length = 340 Score = 434 bits (1117), Expect = e-122, Method: Composition-based stats. Identities = 160/324 (49%), Positives = 222/324 (68%), Gaps = 3/324 (0%) Query: 42 PNAEDMTSKD--YYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGT 99 P D+ + YF SY H+GIHEEMLKD++RT +YR+ ++ N H+FKDKVVLDVG GT Sbjct: 16 PRGSDLQEDEDGVYFSSYGHYGIHEEMLKDKIRTESYRDFIYQNPHIFKDKVVLDVGCGT 75 Query: 100 GILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDII 159 GIL MFAAKAGA+KV+G++ S I A+ I++ NKL+ +T+IKGK+EEV LPVEKVD+I Sbjct: 76 GILSMFAAKAGAKKVLGVDQSEILYQAMDIIRLNKLEDTITLIKGKIEEVHLPVEKVDVI 135 Query: 160 ISEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENV 219 ISEWMGY L +ESML++VL+A++K+LA G ++PD T+ + A+ D +I +W++V Sbjct: 136 ISEWMGYFLLFESMLDSVLYAKNKYLAKGGSVYPDICTISLVAVSDVNKHADRIAFWDDV 195 Query: 220 YGFDMSCIKDVAIKEPLVDVVDPKQLVTNACLIKEVDIYTVKVEDLTFTSPFCLQVKRND 279 YGF MSC+K I E +V+V+DPK L++ C IK +D +T + DL F+S F L++ R Sbjct: 196 YGFKMSCMKKAVIPEAVVEVLDPKTLISEPCGIKHIDCHTTSISDLEFSSDFTLKITRTS 255 Query: 280 YVHALVAYFNIEFTR-CHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEEIFGTIGMR 338 A+ YF+I F + CH R FST P+S THWKQTVF +E +VK GE + G + + Sbjct: 256 MCTAIAGYFDIYFEKNCHNRVVFSTGPQSTKTHWKQTVFLLEKPFSVKAGEALKGKVTVH 315 Query: 339 PNAKNNRDLDFTIDLDFKGQLCEL 362 N K+ R L T+ L+ Q L Sbjct: 316 KNKKDPRSLTVTLTLNNSTQTYGL 339 >1F3L-A nrPDB Length = 321 Score = 428 bits (1100), Expect = e-120, Method: Composition-based stats. Identities = 157/315 (49%), Positives = 214/315 (67%), Gaps = 1/315 (0%) Query: 49 SKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAK 108 YF SY H+GIHEEMLKD+VRT +YR+ ++ N H+FKDKVVLDVG GTGIL MFAAK Sbjct: 6 EDGVYFSSYGHYGIHEEMLKDKVRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAK 65 Query: 109 AGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCL 168 AGA+KVI ++ S I A+ I++ NKL+ + +IKGK+EEV LPVEKVD+IISEWMGY L Sbjct: 66 AGAKKVIAVDQSEILYQAMDIIRLNKLEDTIVLIKGKIEEVSLPVEKVDVIISEWMGYFL 125 Query: 169 FYESMLNTVLHARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIK 228 +ESML++VL+A+ K+LA G ++PD T+ + A+ D +I +W++VYGF+MSC+K Sbjct: 126 LFESMLDSVLYAKSKYLAKGGSVYPDICTISLVAVSDVSKHADRIAFWDDVYGFNMSCMK 185 Query: 229 DVAIKEPLVDVVDPKQLVTNACLIKEVDIYTVKVEDLTFTSPFCLQVKRNDYVHALVAYF 288 I E +V+VVD K L+++ C IK +D +T + DL F+S F L+ + A+ YF Sbjct: 186 KAVIPEAVVEVVDHKTLISDPCDIKHIDCHTTSISDLEFSSDFTLRTTKTAMCTAVAGYF 245 Query: 289 NIEFTR-CHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEEIFGTIGMRPNAKNNRDL 347 +I F + CH R FST P+S THWKQT+F +E VK GE + G I + N K+ R L Sbjct: 246 DIYFEKNCHNRVVFSTGPQSTKTHWKQTIFLLEKPFPVKAGEALKGKITVHKNKKDPRSL 305 Query: 348 DFTIDLDFKGQLCEL 362 T+ L+ Q L Sbjct: 306 IVTLTLNSSTQTYSL 320 >1G6Q-1 nrPDB Length = 328 Score = 419 bits (1078), Expect = e-118, Method: Composition-based stats. Identities = 160/310 (51%), Positives = 218/310 (70%), Gaps = 2/310 (0%) Query: 51 DYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAG 110 DYYFDSY H+GIHEEML+D VRTL+YRN++ N+ LFKDK+VLDVG GTGIL MFAAK G Sbjct: 1 DYYFDSYDHYGIHEEMLQDTVRTLSYRNAIIQNKDLFKDKIVLDVGCGTGILSMFAAKHG 60 Query: 111 ARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFY 170 A+ VIG++ SSI + A ++V+ N +T+++GK+E+V LP KVDIIISEWMGY L Y Sbjct: 61 AKHVIGVDMSSIIEMAKELVELNGFSDKITLLRGKLEDVHLPFPKVDIIISEWMGYFLLY 120 Query: 171 ESMLNTVLHARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDV 230 ESM++TVL+ARD +L GLIFPD+ ++++ +ED QYKD K+++W++VYGFD S + Sbjct: 121 ESMMDTVLYARDHYLVEGGLIFPDKCSIHLAGLEDSQYKDEKLNYWQDVYGFDYSPFVPL 180 Query: 231 AIKEPLVDVVDPKQLVTNACLIKEVDIYTVKVEDLTFTSPFCLQVKRNDYVHALVAYFNI 290 + EP+VD V+ + T + + E D+ TVK+ DL F S F L KR D ++ +V +F+I Sbjct: 181 VLHEPIVDTVERNNVNTTSDKLIEFDLNTVKISDLAFKSNFKLTAKRQDMINGIVTWFDI 240 Query: 291 EF--TRCHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEEIFGTIGMRPNAKNNRDLD 348 F + + FST P +PYTHWKQT+FY D L +TG+ I G + PN KNNRDL+ Sbjct: 241 VFPAPKGKRPVEFSTGPHAPYTHWKQTIFYFPDDLDAETGDTIEGELVCSPNEKNNRDLN 300 Query: 349 FTIDLDFKGQ 358 I F+ Sbjct: 301 IKISYKFESN 310 >6CU3-A nrPDB Length = 336 Score = 412 bits (1058), Expect = e-115, Method: Composition-based stats. Identities = 167/318 (52%), Positives = 218/318 (68%), Gaps = 8/318 (2%) Query: 59 HFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIE 118 GIHEEMLKD +RT Y+N++ N+HLFKDKVVLD+G GTGILC+FAAKAGA++VIGI+ Sbjct: 22 TTGIHEEMLKDGIRTNAYKNAILQNKHLFKDKVVLDIGCGTGILCLFAAKAGAKRVIGID 81 Query: 119 CSSISDYAVKIVKANKLDHVVTIIKGKVEEV-ELP--VEKVDIIISEWMGYCLFYESMLN 175 S I D A +IV N HV+ +IKGKVE++ +LP +EKVDIIISEWMGY L YESML Sbjct: 82 MSDIIDKARQIVSDNGYSHVIELIKGKVEDIAQLPFGIEKVDIIISEWMGYFLLYESMLQ 141 Query: 176 TVLHARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDVAIKEP 235 TVL ARD+WL P G +FPD+ T+Y+ IED +YK KI +W+NVYGF+ S IK A++EP Sbjct: 142 TVLSARDRWLRPGGYLFPDKCTMYICGIEDSEYKRDKIDFWDNVYGFNFSAIKADALREP 201 Query: 236 LVDVVDPKQLVTNACLIKEVDIYTVKVEDL-TFTSPFCLQVKRNDYVHALVAYFNIEFTR 294 LVD V+ +Q++T E+D+ T++ EDL T+ F + +Y A VA+F+ F+R Sbjct: 202 LVDFVESQQIITTQSKFLEIDLNTIQPEDLKQITTSFEFTSQYQEYCQAFVAWFDCVFSR 261 Query: 295 C-HKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEEIFGTIGMRPNAKNNRDLDFTIDL 353 HK FST P + THWKQTVFY+E+ L +K + I GTI + N N+RDLD ++ Sbjct: 262 GPHKPVEFSTGPFTEGTHWKQTVFYLENDLPLKPNDVIKGTITISQNKSNHRDLDISMKY 321 Query: 354 DFKGQLCELSCSTDYRMR 371 G S DY MR Sbjct: 322 TVNGGAV---ISQDYIMR 336 >5JMQ-A nrPDB Length = 446 Score = 391 bits (1005), Expect = e-109, Method: Composition-based stats. Identities = 115/334 (34%), Positives = 186/334 (55%), Gaps = 11/334 (3%) Query: 40 EKPNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGT 99 E+ + ED + YFDSY +H EML D+ RT Y + + N+ KDKV+LDVG GT Sbjct: 102 EEYDPEDTWQDEEYFDSYGTLKLHLEMLADQPRTTKYHSVILQNKESLKDKVILDVGCGT 161 Query: 100 GILCMFAAK-AGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDI 158 GI+ +F A A + V +E S ++ + ++V N +T+ + KVE+V LP EKVD+ Sbjct: 162 GIISLFCAHHARPKAVYAVEASDMAQHTSQLVLQNGFADTITVFQQKVEDVVLP-EKVDV 220 Query: 159 IISEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWEN 218 ++SEWMG CL +E M+ ++L+ARD WL DG+I+P A L++ + K+ +W+N Sbjct: 221 LVSEWMGTCLLFEFMIESILYARDTWLKGDGIIWPTTAALHLVPCSAEKDYHSKVLFWDN 280 Query: 219 VYGFDMSCIKDVAIKEPLVDV-----VDPKQLVTNACLIKEVDIYTVKVEDL-TFTSPFC 272 Y F++S +K +AIKE + P+ ++ C I ++D+ TV+V DL T Sbjct: 281 AYEFNLSALKSLAIKEFFSRPKSNHILKPEDCLSEPCTILQLDMRTVQVPDLETMRGELR 340 Query: 273 LQVKRNDYVHALVAYFNIEFTRCHK---RTGFSTSPESPYTHWKQTVFYMEDYLTVKTGE 329 +++ +H A+F++ F + + ST P P THWKQT+F M+D + V TG+ Sbjct: 341 FDIQKAGTLHGFTAWFSVYFQSLEEGQPQQVLSTGPLHPTTHWKQTLFMMDDPVPVHTGD 400 Query: 330 EIFGTIGMRPNAKNNRDLDFTIDLDFKGQLCELS 363 + G++ ++ N R + ++ L S Sbjct: 401 VVTGSVVLQRNPVWRRHMSVSLSWVVTSALDPTS 434 >5LV5-A nrPDB Length = 403 Score = 389 bits (999), Expect = e-108, Method: Composition-based stats. Identities = 115/330 (34%), Positives = 175/330 (53%), Gaps = 16/330 (4%) Query: 40 EKPNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGT 99 +P Y++ Y+ +HEEM+ D+VRT YR + N + K VLDVG+GT Sbjct: 62 PRPRRTKSERDQLYYECYSDVSVHEEMIADQVRTEAYRLGILKNWAALRGKTVLDVGAGT 121 Query: 100 GILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDII 159 GIL +F A+AGAR+V +E S+I A ++V+ N L+ V ++ G VE VELP E+VD I Sbjct: 122 GILSIFCAQAGARRVYAVEASAIWQQAREVVRLNGLEDRVHVLPGPVETVELP-ERVDAI 180 Query: 160 ISEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENV 219 +SEWMGY L +ESML++VLHAR KWL GL+ P A L+V I D Q ++++ +W V Sbjct: 181 VSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFVAPISD-QMLEWRLGFWSQV 239 Query: 220 ---YGFDMSCIKDVAIK------EPLVDVVDPKQLVTNACLIKEVDIYTVKVE---DLTF 267 YG DMSC++ A + E +V + + ++ ++++ +E + Sbjct: 240 KQHYGVDMSCMESFATRCLMGHSEIVVQDLSGEDVLARPQRFAQLELARAGLEQELEAGV 299 Query: 268 TSPFCLQVKRNDYVHALVAYFNIEFTR--CHKRTGFSTSPESPYTHWKQTVFYMEDYLTV 325 F + +H +F + F K STSP P THWKQ + Y+ + + V Sbjct: 300 GGRFRCSCYGSAPLHGFAVWFQVTFPGGDSEKPLVLSTSPLHPATHWKQALLYLNEPVPV 359 Query: 326 KTGEEIFGTIGMRPNAKNNRDLDFTIDLDF 355 + +I G I + P+ N R L + Sbjct: 360 EQDTDISGEITLLPSPDNPRRLRILLRYKV 389 >5EGS-A nrPDB Length = 376 Score = 388 bits (996), Expect = e-108, Method: Composition-based stats. Identities = 115/333 (34%), Positives = 176/333 (52%), Gaps = 16/333 (4%) Query: 40 EKPNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGT 99 E+P Y++ Y+ +HEEM+ D VRT YR + N + K VLDVG+GT Sbjct: 35 ERPRRTKRERDQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGT 94 Query: 100 GILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDII 159 GIL +F A+AGAR+V +E S+I A ++V+ N L+ V ++ G VE VELP E+VD I Sbjct: 95 GILSIFCAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELP-EQVDAI 153 Query: 160 ISEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENV 219 +SEWMGY L +ESML++VLHAR KWL GL+ P A L++ I D Q ++++ +W V Sbjct: 154 VSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIVPISD-QMLEWRLGFWSQV 212 Query: 220 ---YGFDMSCIKDVAIK------EPLVDVVDPKQLVTNACLIKEVDIYTVKVE---DLTF 267 YG DMSC++ A + E +V + + ++ ++++ +E + Sbjct: 213 KQHYGVDMSCLEGFATRCLMGHSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQELEAGV 272 Query: 268 TSPFCLQVKRNDYVHALVAYFNIEFTR--CHKRTGFSTSPESPYTHWKQTVFYMEDYLTV 325 F + +H +F + F K STSP P THWKQ + Y+ + + V Sbjct: 273 GGRFRCSCYGSAPMHGFAIWFQVTFPGGESEKPLVLSTSPFHPATHWKQALLYLNEPVQV 332 Query: 326 KTGEEIFGTIGMRPNAKNNRDLDFTIDLDFKGQ 358 + ++ G I + P+ N R L + Q Sbjct: 333 EQDTDVSGEITLLPSRDNPRRLRVLLRYKVGDQ 365 >5FUB-A nrPDB Length = 337 Score = 375 bits (962), Expect = e-104, Method: Composition-based stats. Identities = 108/335 (32%), Positives = 175/335 (52%), Gaps = 11/335 (3%) Query: 46 DMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMF 105 D D YF +Y +H EML D+ RT TYR + N ++KVVLD+G GTG++ +F Sbjct: 2 DAWQDDEYFGNYGTLRLHLEMLSDKPRTETYRQVILSNSAALREKVVLDLGCGTGVISLF 61 Query: 106 AAK-AGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWM 164 A A V +E SS++++ ++VK N D VVT+ + + E + LP KVD+++SEWM Sbjct: 62 CALLAKPAGVYAVEASSMAEHTEELVKQNGCDGVVTVFQERAENLTLPT-KVDVLVSEWM 120 Query: 165 GYCLFYESMLNTVLHARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDM 224 G CL +E ML +VL ARD+WL G+++P A L + + K+ +WEN YG + Sbjct: 121 GNCLLFEYMLESVLLARDRWLKKGGMMWPSSACLTIVPCQAFSDYRQKVEFWENPYGLNF 180 Query: 225 SCIKDVAIKEPLVDV-----VDPKQLVTNACLIKEVDIYTVKVEDLTF-TSPFCLQVKRN 278 S ++ +A KE L + P+ ++ + +D+ T++V DL F V+++ Sbjct: 181 SYLQSLAQKEFLSKPKFSHHLQPEDCLSTPADVITLDMVTIQVSDLERLKGEFTFTVEKS 240 Query: 279 DYVHALVAYFNIEFTRCHK---RTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEEIFGTI 335 H +F+ F + +T P S THWKQT+F ++ ++V+ G+ I G+I Sbjct: 241 GMFHGFTVWFSAHFQCLEEDGPSIELNTGPYSEITHWKQTLFMLDAPVSVEEGDIIAGSI 300 Query: 336 GMRPNAKNNRDLDFTIDLDFKGQLCELSCSTDYRM 370 ++ N R L T + + + M Sbjct: 301 RLQRNPIWRRHLSITFLWNINSTEVSTVKTKCFPM 335 >3B3J-A nrPDB Length = 480 Score = 347 bits (891), Expect = 3e-96, Method: Composition-based stats. Identities = 117/337 (34%), Positives = 180/337 (53%), Gaps = 25/337 (7%) Query: 37 ESSEKPNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVG 96 E S + +S YF Y + + M++D VRT TY+ ++ N FKDK+VLDVG Sbjct: 107 ERSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVG 166 Query: 97 SGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKV 156 G+GIL FAA+AGARK+ +E S+++ +A +VK+N L + +I GKVEEV LP E+V Sbjct: 167 CGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLP-EQV 225 Query: 157 DIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRATLYVTAIEDRQY---KDYKI 213 DIIISE MGY LF E ML + LHA+ K+L P G +FP +++ D Q + K Sbjct: 226 DIIISEPMGYMLFNERMLESYLHAK-KYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKA 284 Query: 214 HWW--ENVYGFDMSCIKDVAI----KEPLVDVVDPKQLVT-------NACLIKEVDIYTV 260 ++W + +G D+S ++ A+ ++P+VD D + L+ N KE D++ + Sbjct: 285 NFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRI 344 Query: 261 KVEDLTFTSPFCLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYME 320 ++ PF + + VH L +F++ F ST+P P THW Q + Sbjct: 345 EI-------PFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQ 397 Query: 321 DYLTVKTGEEIFGTIGMRPNAKNNRDLDFTIDLDFKG 357 L K G+ + GT + N + + D+ +D G Sbjct: 398 SPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTG 434 >4IKP-A nrPDB Length = 341 Score = 346 bits (887), Expect = 1e-95, Method: Composition-based stats. Identities = 115/330 (34%), Positives = 178/330 (53%), Gaps = 25/330 (7%) Query: 44 AEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILC 103 + +S YF Y + + M++D VRT TY+ ++ N FKDK+VLDVG G+GIL Sbjct: 1 RTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILS 60 Query: 104 MFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEW 163 FAA+AGARK+ +E S+++ +A +VK+N L + +I GKVEEV LP E+VDIIISE Sbjct: 61 FFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLP-EQVDIIISEP 119 Query: 164 MGYCLFYESMLNTVLHARDKWLAPDGLIFPDRATLYVTAIEDRQY---KDYKIHWW--EN 218 MGY LF E ML + LHA+ K+L P G +FP +++ D Q + K ++W + Sbjct: 120 MGYMLFNERMLESYLHAK-KYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPS 178 Query: 219 VYGFDMSCIKDVAI----KEPLVDVVDPKQLVT-------NACLIKEVDIYTVKVEDLTF 267 +G D+S ++ A+ ++P+VD D + L+ N KE D++ +++ Sbjct: 179 FHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIEI----- 233 Query: 268 TSPFCLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKT 327 PF + + VH L +F++ F ST+P P THW Q + L K Sbjct: 234 --PFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKA 291 Query: 328 GEEIFGTIGMRPNAKNNRDLDFTIDLDFKG 357 G+ + GT + N + + D+ +D G Sbjct: 292 GDTLSGTCLLIANKRQSYDISIVAQVDQTG 321 >5IS8-A nrPDB Length = 381 Score = 344 bits (883), Expect = 3e-95, Method: Composition-based stats. Identities = 117/337 (34%), Positives = 180/337 (53%), Gaps = 25/337 (7%) Query: 37 ESSEKPNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVG 96 E S + +S YF Y + + M++D VRT TY+ ++ N FKDK+VLDVG Sbjct: 8 ERSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVG 67 Query: 97 SGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKV 156 G+GIL FAA+AGARK+ +E S+++ +A +VK+N L + +I GKVEEV LP E+V Sbjct: 68 CGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLP-EQV 126 Query: 157 DIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRATLYVTAIEDRQY---KDYKI 213 DIIISE MGY LF E ML + LHA+ K+L P G +FP +++ D Q + K Sbjct: 127 DIIISEPMGYMLFNERMLESYLHAK-KYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKA 185 Query: 214 HWW--ENVYGFDMSCIKDVAI----KEPLVDVVDPKQLVT-------NACLIKEVDIYTV 260 ++W + +G D+S ++ A+ ++P+VD D + L+ N KE D++ + Sbjct: 186 NFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRI 245 Query: 261 KVEDLTFTSPFCLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYME 320 ++ PF + + VH L +F++ F ST+P P THW Q + Sbjct: 246 EI-------PFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQ 298 Query: 321 DYLTVKTGEEIFGTIGMRPNAKNNRDLDFTIDLDFKG 357 L K G+ + GT + N + + D+ +D G Sbjct: 299 SPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTG 335 >3R0Q-C nrPDB Length = 376 Score = 337 bits (865), Expect = 4e-93, Method: Composition-based stats. Identities = 110/334 (32%), Positives = 190/334 (56%), Gaps = 30/334 (8%) Query: 52 YYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGA 111 YF +Y+ ++ML D VR Y N++F N+H F+ K VLDVG+G+GIL +++A+AGA Sbjct: 27 QYFCTYSFLYHQKDMLSDRVRMDAYFNAVFQNKHHFEGKTVLDVGTGSGILAIWSAQAGA 86 Query: 112 RKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYE 171 RKV +E + ++D+A +VKAN LDH+V +I+G VE++ LP EKVD+IISEWMGY L E Sbjct: 87 RKVYAVEATKMADHARALVKANNLDHIVEVIEGSVEDISLP-EKVDVIISEWMGYFLLRE 145 Query: 172 SMLNTVLHARDKWLAPDGLIFPDRATLYVTAIE----DRQYKDY--KIHWWENV------ 219 SM ++V+ ARD+WL P G+++P A +++ I+ DR+ D+ + W N Sbjct: 146 SMFDSVISARDRWLKPTGVMYPSHARMWLAPIKSNIADRKRNDFDGAMADWHNFSDEIKS 205 Query: 220 -YGFDMSCI--------KDVAIKEPLVDVVDPKQLVTNACLIKEVDIYTVKVEDLTFTSP 270 YG DM + + I+ + + ++P+Q++ ++KE+D T V ++ Sbjct: 206 YYGVDMGVLTKPFAEEQEKYYIQTAMWNDLNPQQIIGTPTIVKEMDCLTASVSEIEEVRS 265 Query: 271 FCLQVKRNDYVH--ALVAYFNIEFTR-----CHKRTGFSTSPESPY-THWKQTVFYMEDY 322 V ++ +F+++F+ + +T+P + THW Q VF M + Sbjct: 266 NVTSVINMEHTRLCGFGGWFDVQFSGRKEDPAQQEIELTTAPSEQHCTHWGQQVFIMSNP 325 Query: 323 LTVKTGEEIFGTIGMRPNAKNNRDLDFTIDLDFK 356 + V+ G+ + + M + +N+R ++ ++ + K Sbjct: 326 INVEEGDNLNLGLLMSRSKENHRLMEIELNCEIK 359 >4LWO-B nrPDB Length = 368 Score = 278 bits (710), Expect = 3e-75, Method: Composition-based stats. Identities = 107/353 (30%), Positives = 170/353 (48%), Gaps = 53/353 (15%) Query: 52 YYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGA 111 Y++SY+ +H ML+D R YR S+ + + + KVV+DVGSGTGIL M+AA+AGA Sbjct: 19 QYYESYSDLAVHRLMLEDAQRMSFYRKSIEQSASI-EGKVVVDVGSGTGILSMWAARAGA 77 Query: 112 RKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEV--------------ELPVEKVD 157 + V IE SS+S++ + +V+ N L +T++ VE + +L V Sbjct: 78 KHVFSIEASSLSEFQIGVVEDNDLSTKITVLGDTVENIIAGGVANFVNRHKAKLGKCGVA 137 Query: 158 IIISEWMGYCLFYESMLNTVLHARDKW---------LAPDGLIFPDRATLYVTAIEDRQY 208 +++SEWMG+ LF+E ML +V+ AR+ + L P + P+RAT++V I + Y Sbjct: 138 VLLSEWMGFYLFHEGMLPSVIRARNFFQDVNAALGVLQPI-EMIPERATVFVAPITCKPY 196 Query: 209 KDYKI-HWWENVYGFDMSCIKDVAIK------EPLVDVVDPKQLVTNACLIKEVDIYTVK 261 + ++W +V G D S + + PLV+ + P L+ + E+++ TV+ Sbjct: 197 YVQRYKNFWRDVDGLDFSRYGRIEYEVYLEQASPLVECLPPLCLLHEGLSLIELNLSTVQ 256 Query: 262 VEDLTF---TSPFCLQVKRNDYVHAL---------VAYFNIEFTRCHKRTGFSTSPESPY 309 E LT T F L+ HA V F + F + STSP SP Sbjct: 257 EEVLTSLHNTVHFDLKESAEFQQHAREAGSEGRVSVDGFTVWFDVSYGAHTLSTSPRSPS 316 Query: 310 THWKQTVFYMEDY--------LTVKTGEEIFGTIGMRPNAKNNRDLDFTIDLD 354 THWKQT + V+ GE + + + + K R ++L Sbjct: 317 THWKQTTILLPREARNEELVSFPVEGGE-LGVEMHISASDKTLRFYTIELELK 368 >5EKU-A nrPDB Length = 390 Score = 242 bits (618), Expect = 2e-64, Method: Composition-based stats. Identities = 69/282 (24%), Positives = 128/282 (45%), Gaps = 28/282 (9%) Query: 63 HEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSS- 121 H M+ DE R Y + +H+ + VL++G+G+G+L + AAK GA+ V+ +E S Sbjct: 72 HYAMMNDEERNNFYYEVL--KKHVTPETGVLEIGAGSGLLSLMAAKLGAKWVVAVEGSEE 129 Query: 122 ISDYAVKIVKANKLDHVVTIIKGKVEEVE---LPVEKVDIIISEWMGYCLFYESMLNTVL 178 ++ A + ++AN ++H V ++ E++ LP E D+++SE G + ES L+ V+ Sbjct: 130 LAKLARENIRANNMEHQVKVLHMMSTELKPKHLP-EPPDVLLSEIFGTMMLGESALDYVV 188 Query: 179 HARDKWLAPDGLIFPDRATLYVTAIE-DRQYKDYKIHWWENVYGFDMSCIKDVAI----- 232 R++ L P I P T Y IE D ++ + W ++ M ++D Sbjct: 189 DVRNRLLKPTTKIIPQFGTQYAVPIECDALHRISSVSGWRDLDLKHMMTLQDTVSIVFAK 248 Query: 233 -KEPLVDVVDPKQLVTNACLIKEVDIYTVKVEDLTFTSPFCLQVKRNDYVHALVAYFNIE 291 ++ V+ ++L L + VD + D++ F + K + HA++ Y+ + Sbjct: 249 HYGIRMNSVNFRRLSDPIELFR-VDFSSSNRNDISRRKHFDVVAKESGTAHAMLFYWKVT 307 Query: 292 FTRCHKRTGFSTSPESPYTH------WKQTVFYMED---YLT 324 ST PE + W Q + ++ L Sbjct: 308 ----DDEFVMSTDPEDTVNNFPRDMQWGQALQLLDASNGPLP 345 >4M36-A nrPDB Length = 343 Score = 242 bits (617), Expect = 2e-64, Method: Composition-based stats. Identities = 69/282 (24%), Positives = 127/282 (45%), Gaps = 28/282 (9%) Query: 63 HEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSS- 121 H M+ DE R Y + +H+ + VL++G+G+G+L + AAK GA+ V+ +E S Sbjct: 37 HYAMMNDEERNNFYYEVL--KKHVTPETGVLEIGAGSGLLSLMAAKLGAKWVVAVEGSEE 94 Query: 122 ISDYAVKIVKANKLDHVVTIIKGKVEEVE---LPVEKVDIIISEWMGYCLFYESMLNTVL 178 ++ A + ++AN ++H V ++ E++ LP E D+++SE G + ES L+ V+ Sbjct: 95 LAKLARENIRANNMEHQVKVLHMMSTELKSKHLP-EPPDVLLSEIFGTMMLGESALDYVV 153 Query: 179 HARDKWLAPDGLIFPDRATLYVTAIE-DRQYKDYKIHWWENVYGFDMSCIKDVAI----- 232 R++ L P I P T Y IE D ++ + W ++ M ++D Sbjct: 154 DVRNRLLKPTTKIIPQFGTQYAVPIECDALHRISSVSGWRDLDLKHMMTLQDTVSIVFAK 213 Query: 233 -KEPLVDVVDPKQLVTNACLIKEVDIYTVKVEDLTFTSPFCLQVKRNDYVHALVAYFNIE 291 ++ V+ ++L L + VD + D+ F + K + HA++ Y+ + Sbjct: 214 HYGIRMNSVNFRRLSDPIELFR-VDFSSSNRNDIPRRKHFDVVAKESGTAHAMLFYWKVT 272 Query: 292 FTRCHKRTGFSTSPESPYTH------WKQTVFYMED---YLT 324 ST PE + W Q + ++ L Sbjct: 273 ----DDEFVMSTDPEDTVNNFPRDMQWGQALQLLDASNGPLP 310 >6OGN-A nrPDB Length = 692 Score = 205 bits (521), Expect = 3e-53, Method: Composition-based stats. Identities = 74/340 (21%), Positives = 133/340 (39%), Gaps = 52/340 (15%) Query: 30 EVSCGQAESSEKPNAEDMTSKDYYFDSYAHFG--IHEEMLKDEVRTLTYRNSMFHNRHLF 87 +V CG+A + + + +D ++D + + +ML D+ R + Y + Sbjct: 2 KVFCGRANPTT--GSLEWLEEDEHYDYHQEIARSSYADMLHDKDRNIKYYQGIRAAVSRV 59 Query: 88 KDK----VVLDVGSGTGILCMFAAKAGARKVIGIEC-SSISDYAVKIVKANKLDHVVTII 142 KD+ +VLD+G+GTG+L M A AGA IE +++ AVKIV+ N + +I Sbjct: 60 KDRGQKALVLDIGTGTGLLSMMAVTAGADFCYAIEVFKPMAEAAVKIVERNGFSDKIKVI 119 Query: 143 KGKVEEVELPV-----EKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRAT 197 EV + + +I+I+E L E L + HA + D P RAT Sbjct: 120 NKHSTEVTVGPDGDLPCRANILITELFDTELIGEGALPSYEHAHKHLVQEDCEAVPHRAT 179 Query: 198 LYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDVAIKEPLVDVVDPKQLVTNACLIKEVDI 257 +Y +E R+ W ++ ++ ++ +V + ++ + ++ + Sbjct: 180 VYAQLVESRRMWS-----WNKLFPV---RVRTSLGEQVIVPPSELERCPGAP-SVCDIQL 230 Query: 258 YTVKVEDLT--------FTSPFCLQVKRNDYVHALVA-------------YFNIEFTRCH 296 V D T F+ F QV + H+ +++IE Sbjct: 231 NQVSPADFTVLSDVLPMFSVDFSKQVSSSAACHSRQFVPLASGQAQVVLSWWDIEMDPEG 290 Query: 297 K------RTGFSTSPESPY--THWKQTVFYMEDYLTVKTG 328 K T P+ HW Q V+++ V G Sbjct: 291 KIKCTMAPFWAQTDPQELQWRDHWMQCVYFLPQEEPVVQG 330 Score = 78.2 bits (191), Expect = 6e-15, Method: Composition-based stats. Identities = 62/294 (21%), Positives = 112/294 (38%), Gaps = 50/294 (17%) Query: 67 LKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYA 126 + D+ RT Y ++ L V L V G+ +L M A GA +V +E S S Sbjct: 382 INDQDRTDHYAQALRT--VLLPGSVCLCVSDGS-LLSMLAHHLGAEQVFTVESSVASYRL 438 Query: 127 VK-IVKANKLDHVVTIIKGKVEEV---ELPVEKVDIIISEWMGYCLF---YESMLNTVLH 179 +K I K N L+ +++I + E + +L +KV +++ E + V Sbjct: 439 MKRIFKVNHLEDKISVINKRPELLTAADLEGKKVSLLLGEPFFTTSLLPWHNLYFWYVRT 498 Query: 180 ARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWE------NVYGFDMSCIKDV--- 230 + D+ LAP ++ P A+L+ +E R W + GFD+ + D+ Sbjct: 499 SVDQHLAPGAVVMPQAASLHAVIVEFR-------DLWRIRSPCGDCEGFDVHIMDDMIKH 551 Query: 231 ---------AIKEPLVDVVDPKQLVTNACLIKEVDIYTVKVEDLTFTSPFCLQVKRNDYV 281 A PL + P + ++ I D + + +++ R Sbjct: 552 SLDFRESREAEPHPLWEY--PCRSLSKPQEILTFDFQQPIPQQPMQSKG-TMELTRPGKS 608 Query: 282 HALVAYFNIEFTRCHKRTGFSTSPESPYT---------HWKQTVFYMEDYLTVK 326 H V + + T + ST +P H KQ V+++ L ++ Sbjct: 609 HGAVLWMEYQLT---PDSTISTGLINPAEDKGDCCWNPHCKQAVYFLSTTLDLR 659 >4G56-A nrPDB Length = 657 Score = 179 bits (454), Expect = 2e-45, Method: Composition-based stats. Identities = 72/326 (22%), Positives = 132/326 (40%), Gaps = 45/326 (13%) Query: 36 AESSEKPNAEDMTSKDY--YFDSYAH-------FGIHEEMLKDEVRTLTYRNSMFH---N 83 +++S PNA +M +K Y Y S +E KD V+ Y+ +++ + Sbjct: 308 SQNSPPPNAYEMFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPVKYSQYQQAVYKCLLD 367 Query: 84 RHLFKDK-----VVLDVGSGTGIL---CMFAAKAGARK--VIGIECSSISDYAVKIVKAN 133 R ++K +++ +G+G G L + AAK RK V +E + + ++ + Sbjct: 368 RVPEEEKETNIQILMVLGAGRGPLVNASLRAAKQAERKIKVYAVEKNPNAVITLEGWRYE 427 Query: 134 KLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNT-VLHARDKWLAPDGLIF 192 + VT++ G + E + P EK DII+SE +G F ++ L+ L +L DG+ Sbjct: 428 EWGSQVTVVSGDMREWKAP-EKADIIVSELLGS--FGDNELSPECLDGAQHFLKDDGVSI 484 Query: 193 PDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDVAIKEPLVDVVDPKQLVTN-ACL 251 P T Y+ I + + D + +V + + QL C Sbjct: 485 PGEYTSYLAPISSSKLYNEV----RACREKDRDPEAQFEMP-YVVRLHNFHQLSDPLPC- 538 Query: 252 IKEVDIYTVKVEDLTFTSPFCLQVKRNDY---VHALVAYFNIEFTRCHKRTGFSTSPESP 308 + +D+ + +C R D +H YFN T +K S PES Sbjct: 539 ---FTFHHPNKDDVIDNNRYCCLQYRVDLNTVLHGFAGYFN---TVLYKDVTLSICPESH 592 Query: 309 YT---HWKQTVFYMEDYLTVKTGEEI 331 W +F ++ + ++ G+ + Sbjct: 593 SPGMFSWFPILFPIKQPIPMREGDTV 618 >3X0D-A nrPDB Length = 655 Score = 165 bits (417), Expect = 3e-41, Method: Composition-based stats. Identities = 59/318 (18%), Positives = 119/318 (37%), Gaps = 27/318 (8%) Query: 39 SEKPNAEDMTSKDYYFDSYAHFGIHE--EMLKDEVRTLTYRNSM-----FHNRHLFKDKV 91 ++K + + +D +M+ D R + + KV Sbjct: 15 NQKTGEREWVVAEEDYDMAQELARSRFGDMILDFDRNDKFLAGLKTTIAEKKHENTDGKV 74 Query: 92 -VLDVGSGTGILCMFAAKAGARKVIGIEC-SSISDYAVKIVKANKLDHVVTIIKGKVEEV 149 VLD+G+GTG+L + AA+ GA KV +E + D A I + +T+I + +V Sbjct: 75 HVLDIGTGTGLLSLMAAREGADKVTALEVFKPMGDCARHITSNSPWSDKITVISERSTDV 134 Query: 150 -ELPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRATLYVTAIEDRQY 208 ++ + DII++E L E L T A ++ P + P +Y+ +E Sbjct: 135 SQIGGSRADIIVAEVFDTELIGEGALRTFKEALERLAKPGCRVVPSTGNVYIVPVESHLL 194 Query: 209 KDY----KIHWWEN--VYGFDMSCIKDVAIKEPLVDVVDPKQLVTNACLIKEVDIYTVKV 262 K + +++ ++ G ++ + + ++L K D Sbjct: 195 KMFNDIPRLNGEKDEEPLGRCSGTAAVFDVQLSEMKTHEFRELSEPIVAFK-FDFE--HE 251 Query: 263 EDLTFTSPF--CLQVKRNDYVHALVAYFNIEFTRC------HKRTGFSTSPESPYTHWKQ 314 E + F F + + AL+ +++I+ R + + + HW Q Sbjct: 252 EKIIFDESFVREAVAHSSGTIDALLMWWDIDMDRNGTTFIDMGPKWKNKNNYAWRDHWMQ 311 Query: 315 TVFYMEDYLTVKTGEEIF 332 V+Y+ + V+ + Sbjct: 312 AVYYLPEKKKVEMNQTFE 329 >5FA5-A nrPDB Length = 650 Score = 161 bits (407), Expect = 5e-40, Method: Composition-based stats. Identities = 68/339 (20%), Positives = 128/339 (37%), Gaps = 50/339 (14%) Query: 29 EEVSCGQ-------AESSEKPNAEDMTSKDY--YFDSYAH-------FGIHEEMLKDEVR 72 E+ C +++ PNA ++ +K Y Y S +E KD ++ Sbjct: 287 EKEFCSYLQYLEYLSQNRPPPNAYELFAKGYEDYLQSPLQPLMDNLESQTYEVFEKDPIK 346 Query: 73 TLTYRNSMFH---NRHLFKDK-----VVLDVGSGTGIL---CMFAAKAGARKV--IGIEC 119 Y+ +++ +R ++K V++ +G+G G L + AAK R++ +E Sbjct: 347 YSQYQQAIYKCLLDRVPEEEKDTNVQVLMVLGAGRGPLVNASLRAAKQADRRIKLYAVEK 406 Query: 120 SSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNT-VL 178 + + ++ + + VT++ + E P EK DII+SE +G F ++ L+ L Sbjct: 407 NPNAVVTLENWQFEEWGSQVTVVSSDMREWVAP-EKADIIVSELLGS--FADNELSPECL 463 Query: 179 HARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDVAIKEPLVD 238 +L DG+ P T ++ I + + D + +V Sbjct: 464 DGAQHFLKDDGVSIPGEYTSFLAPISSSKLYNEV----RACREKDRDPEAQFEMP-YVVR 518 Query: 239 VVDPKQLVTNACLIKEVDIYTVKVEDLTFTSPFCLQVKRNDYVHALVAYFNIEFTRCHKR 298 + + QL + D V+ N +H YF T ++ Sbjct: 519 LHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFPVEVNTVLHGFAGYFE---TVLYQD 575 Query: 299 TGFSTSPESPYTH------WKQTVFYMEDYLTVKTGEEI 331 S PE TH W +F ++ +TV+ G+ I Sbjct: 576 ITLSIRPE---THSPGMFSWFPILFPIKQPITVREGQTI 611 >3UA4-A nrPDB Length = 745 Score = 78.2 bits (191), Expect = 5e-15, Method: Composition-based stats. Identities = 55/333 (16%), Positives = 103/333 (30%), Gaps = 67/333 (20%) Query: 59 HFGIHEEMLKDEVRTLTYRNSMFHNRHLF-----KDKVVLDVGSGTGIL----------- 102 G++ +D+++ Y ++ K V+ +G G G + Sbjct: 375 DSGVYNTFEQDQIKYDVYGEAVVGALKDLGADGRKTVVIYLLGGGRGPIGTKILKSEREY 434 Query: 103 --CMFAAKAGAR-KVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEV-----ELPVE 154 + + K+ +E + + +K + VTII+ + + + E Sbjct: 435 NNTFRQGQESLKVKLYIVEKNPNAIVTLKYMNVRTWKRRVTIIESDMRSLPGIAKDRGFE 494 Query: 155 KVDIIISEWMGYCLFYESMLNT-VLHARDKWLAPDGLIFPDRATLYVTAI-EDRQYKDYK 212 + DII+SE +G F ++ L+ L +L P + P + T YV I ++ K Sbjct: 495 QPDIIVSELLGS--FGDNELSPECLDGVTGFLKPTTISIPQKYTSYVKPIMSTHIHQTIK 552 Query: 213 I-----------------------HWWENVYGF-DMSCIKDVAIKEPLVDVVDPKQLVTN 248 W Y + D L + + Sbjct: 553 AQSIPYLSRAIPSHGRGEPELDEDEMWIQKYPQGHVRNNMDQIYVVYLSKYIPLAETTKP 612 Query: 249 ACLIKEVDIYTVKVEDLTFTSPFCLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSPESP 308 + + E + + RN + YF+++ +K S P Sbjct: 613 VFTFEHPNFMNSSNE---RSDSIEFVMDRNADLMGFAGYFDLQL---YKTVMLS---IEP 663 Query: 309 YTH------WKQTVFYMEDYLTVKTGEEIFGTI 335 TH W V + D L V G+ I I Sbjct: 664 STHTPGMVSWFPAVIPLRDQLRVGEGDRISLKI 696 >2AS0-A nrPDB Length = 396 Score = 54.7 bits (130), Expect = 6e-08, Method: Composition-based stats. Identities = 49/222 (22%), Positives = 93/222 (41%), Gaps = 23/222 (10%) Query: 1 MAAAEAANCIMENFVATLANG-MSLQPPLEEVS---CGQAESSEK-PNAEDMTSKDYYFD 55 +A+ + ++ ME F +A M ++P +E V G++ E P E + + Sbjct: 120 IASLQISSAGMERFKLDVAEAIMEVEPGIETVFEKNTGRSRRREGLPEIERVLLGKEKYR 179 Query: 56 SYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKV-----VLDVGSGTGILCMFAAKAG 110 + G + ++ + + NR + V VLDV + TG + AA AG Sbjct: 180 TIIQEGRAKFIVDMRGQKTGFFLDQRENRLALEKWVQPGDRVLDVFTYTGGFAIHAAIAG 239 Query: 111 ARKVIGIECSSIS-DYAVKIVKANKLDHVVTIIKGK----VEEVELPVEKVDIIISEWMG 165 A +VIGI+ S + + A + K N ++ + I G +E+++ EK DI++ + Sbjct: 240 ADEVIGIDKSPRAIETAKENAKLNGVEDRMKFIVGSAFEEMEKLQKKGEKFDIVVLDP-P 298 Query: 166 YCLFYESMLNT-------VLHARDKWLAPDGLIFPDRATLYV 200 + +E L V A + G++ + +V Sbjct: 299 AFVQHEKDLKAGLRAYFNVNFAGLNLVKDGGILVTCSCSQHV 340 >5Z9O-A nrPDB Length = 399 Score = 50.5 bits (119), Expect = 1e-06, Method: Composition-based stats. Identities = 31/115 (26%), Positives = 50/115 (43%), Gaps = 6/115 (5%) Query: 80 MFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECS-SISDYAVKIVKANKLDHV 138 + + H K K +LD+G G G L + AAK KV G+ S K + L+ V Sbjct: 157 ILNKLHPEKGKTLLDIGCGWGTLMLTAAKEYGLKVTGVTLSEEQYKLVQKKIYDEGLEDV 216 Query: 139 VTIIKGKVEEV-ELPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIF 192 + K+E+ EL ++ D + S M + E++ K+L DG+ Sbjct: 217 AEV---KLEDYRELGDQQWDYVTSVGMFEHVGSENLGEYFKDVA-KYLKNDGVAL 267 >3DLC-A nrPDB Length = 219 Score = 49.3 bits (116), Expect = 3e-06, Method: Composition-based stats. Identities = 23/101 (22%), Positives = 46/101 (45%), Gaps = 4/101 (3%) Query: 93 LDVGSGTGILCMFAAKAGARKVIGIECSS-ISDYAVKIVKANKLDHVVTIIKGKVEEVEL 151 +D+GSG G L + AK + ++ S +++ A+K + L+ + I++G V + + Sbjct: 48 IDIGSGPGALSIALAKQSDFSIRALDFSKHMNEIALKNIADANLNDRIQIVQGDVHNIPI 107 Query: 152 PVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIF 192 D+I+S G F+E + + L G + Sbjct: 108 EDNYADLIVSR--GSVFFWEDVATAFREIY-RILKSGGKTY 145 >1L3B-A nrPDB Length = 192 Score = 48.9 bits (115), Expect = 3e-06, Method: Composition-based stats. Identities = 26/106 (24%), Positives = 46/106 (43%), Gaps = 8/106 (7%) Query: 88 KDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKI-VKANKLDHVVTIIKGKV 146 K+ V +DVG GTG + + A R+V I+ + + ++ ++ + L VT+++G Sbjct: 33 KNDVAVDVGCGTGGVTLELA-GRVRRVYAIDRNPEAISTTEMNLQRHGLGDNVTLMEGDA 91 Query: 147 EEVELPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIF 192 E + +DI + G L +L L P G I Sbjct: 92 PEALCKIPDIDIAVVGGSG------GELQEILRIIKDKLKPGGRII 131 >3SVZ-A nrPDB Length = 263 Score = 48.2 bits (113), Expect = 6e-06, Method: Composition-based stats. Identities = 38/153 (24%), Positives = 61/153 (39%), Gaps = 20/153 (13%) Query: 74 LTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSS--ISDYAVKIVK 131 R ++ L D + D+G GTG +F A ++ GI+ I + VK Sbjct: 38 EATRKAVSFINELTDDAKIADIGCGTGGQTLFLADYVKGQITGIDLFPDFIEIFNENAVK 97 Query: 132 ANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLI 191 AN V I G ++ + E++D+I SE Y + +E +N K+L G I Sbjct: 98 AN-CADRVKGITGSMDNLPFQNEELDLIWSEGAIYNIGFERGMNEW----SKYLKKGGFI 152 Query: 192 FPDRATLYV----TAIEDRQYKDYKIHWWENVY 220 A+ + IED +W + Y Sbjct: 153 AVSEASWFTSERPAEIED---------FWMDAY 176 >1WY7-A nrPDB Length = 207 Score = 47.8 bits (112), Expect = 8e-06, Method: Composition-based stats. Identities = 29/112 (25%), Positives = 48/112 (42%), Gaps = 18/112 (16%) Query: 87 FKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKAN--KLDHVVTIIKG 144 + KVV D+G+GTG+L A GA++VI +E AV ++ N + + G Sbjct: 48 IEGKVVADLGAGTGVLSYGALLLGAKEVICVEVD---KEAVDVLIENLGEFKGKFKVFIG 104 Query: 145 KVEEVELPVEKVDIII-SEWMGY--------CLFYESMLNTVLHARDKWLAP 187 V E +VDI+I + G L ++ V+++ P Sbjct: 105 DVSEFN---SRVDIVIMNPPFGSQRKHADRPFLLKAFEISDVVYSI-HLAKP 152 >3LPM-A nrPDB Length = 259 Score = 46.6 bits (109), Expect = 2e-05, Method: Composition-based stats. Identities = 21/75 (28%), Positives = 44/75 (58%), Gaps = 4/75 (5%) Query: 88 KDKVVLDVGSGTGILCMFAAKAGARKVIGIECSS-ISDYAVKIVKANKLDHVVTIIKGKV 146 K K++ D+ SG GI+ + + K++G+E ++D A + V N+L+ + II+ + Sbjct: 50 KGKII-DLCSGNGIIPLLLSTRTKAKIVGVEIQERLADMAKRSVAYNQLEDQIEIIEYDL 108 Query: 147 EEVE--LPVEKVDII 159 +++ +P E+ DI+ Sbjct: 109 KKITDLIPKERADIV 123 >2ZZN-A nrPDB Length = 336 Score = 45.1 bits (105), Expect = 5e-05, Method: Composition-based stats. Identities = 19/67 (28%), Positives = 35/67 (52%), Gaps = 3/67 (4%) Query: 91 VVLDVGSGTGILCMFAAKAGARKVIGIECSSIS-DYAVKIVKANKLDHVVTIIKGKVEEV 149 VV+D+ +G G + A+K+ I+ + + + K +K NKL+H + I V EV Sbjct: 198 VVVDMFAGVGPFSIAC--KNAKKIYAIDINPHAIELLKKNIKLNKLEHKIIPILSDVREV 255 Query: 150 ELPVEKV 156 ++ +V Sbjct: 256 DVKGNRV 262 >5WP5-A nrPDB Length = 491 Score = 44.7 bits (104), Expect = 7e-05, Method: Composition-based stats. Identities = 31/168 (18%), Positives = 62/168 (36%), Gaps = 14/168 (8%) Query: 39 SEKPNAEDMTSKDYYFDSYAHFGIHEEML----KDEVRTLTYRNSMFHNRHLFKDKVVLD 94 + E K Y+ + + + ML D + R + ++ K VL+ Sbjct: 2 ATPYKEERDIQKSYWMEHSSDLTVEAMMLDSKASDLDKEE--RPEVLSLIPPYEGKSVLE 59 Query: 95 VGSGTGILC-MFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVE--EVEL 151 +G+G G A KAG VI ++ + + V N + + V ++++ Sbjct: 60 LGAGIGRFTGELAQKAGE--VIALDFIESAIQKNESV--NGHYKNIKFMCADVTSPDLKI 115 Query: 152 PVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRATLY 199 +D+I S W+ + + + W+ P G IF + + Sbjct: 116 KDGSIDLIFSNWL-LMYLSDKEVELMAERMIGWVKPGGYIFFRESCFH 162 Score = 37.4 bits (85), Expect = 0.011, Method: Composition-based stats. Identities = 36/170 (21%), Positives = 56/170 (32%), Gaps = 26/170 (15%) Query: 35 QAESSEKPNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYR--NSMFHNRHLFKDKVV 92 Q S E + + S + V T + L + V Sbjct: 227 QKVSVENDKDFQRFLDNVQYKSSGILRYERVFGEGYVSTGGFETTKEFVAKMDLKPGQKV 286 Query: 93 LDVGSGTGILCMFAAKAGARKVIGIECS-SISDYAVKIVKANKLDHVVTIIKGKVEEVEL 151 LDVG G G + A+ V+GI+ S ++ +A++ +A L V Sbjct: 287 LDVGCGIGGGDFYMAENFDVHVVGIDLSVNMISFALE--RAIGLKCSVEFEVADCTTKTY 344 Query: 152 PVEKVDIIISEWMGYCLFYESMLNTVLHARD---------KWLAPDGLIF 192 P D+I S +T+LH +D KWL P G + Sbjct: 345 PDNSFDVIYSR------------DTILHIQDKPALFRTFFKWLKPGGKVL 382 >3CJR-A nrPDB Length = 254 Score = 44.3 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 26/111 (23%), Positives = 44/111 (39%), Gaps = 11/111 (9%) Query: 83 NRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSI-SDYAVKIVKANKLDHVVTI 141 RHL VLD+G+G+G+L + A K G + + G++ + A K N + Sbjct: 115 ARHLRPGDKVLDLGTGSGVLAIAAEKLGGKAL-GVDIDPMVLPQAEANAKRNGVRPR--- 170 Query: 142 IKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIF 192 E LP D++++ Y + ++ A L P G Sbjct: 171 FLEGSLEAALPFGPFDLLVANL--YAELHAALAPRYREA----LVPGGRAL 215 >3A26-A nrPDB Length = 301 Score = 43.5 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 36/159 (22%), Positives = 68/159 (42%), Gaps = 14/159 (8%) Query: 77 RNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSIS-DYAVKIVKANKL 135 + + + D++V+D+ +G G L + A G KVI IE + + V+ + NK+ Sbjct: 137 KERVRMAKVAKPDELVVDMFAGIGHLSLPIAVYGKAKVIAIEKDPYTFKFLVENIHLNKV 196 Query: 136 DHVVTIIKGKVEEVELPVEK-VDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPD 194 + ++ + P E D I+ MGY + + L +A DG I Sbjct: 197 EDRMSAYNMDNRD--FPGENIADRIL---MGYVVRTHEFIPKALS-----IAKDGAIIHY 246 Query: 195 RATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDVAIK 233 T+ + ++ +K E YG+D+ + ++ IK Sbjct: 247 HNTVPEKLMPREPFETFKRITKE--YGYDVEKLNELKIK 283 >4LG1-A nrPDB Length = 224 Score = 43.5 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 32/100 (32%), Positives = 49/100 (49%), Gaps = 11/100 (11%) Query: 84 RHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVT-II 142 H + VL++GSGTG + + AA GA V+ + + D + NK H+VT + Sbjct: 58 AHALSRRSVLELGSGTGAVGLMAATLGAD-VVVTDLEELQDLLKMNINMNK--HLVTGSV 114 Query: 143 KGKV----EEVELPVEKVDIIISEWMGYCLFYESMLNTVL 178 + KV EE+E D I+ M C++YE L +L Sbjct: 115 QAKVLKWGEEIEGFPSPPDFIL---MADCIYYEESLEPLL 151 >5WP4-A nrPDB Length = 491 Score = 42.4 bits (98), Expect = 3e-04, Method: Composition-based stats. Identities = 52/270 (19%), Positives = 91/270 (33%), Gaps = 44/270 (16%) Query: 35 QAESSEKPNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRT---LTYRNSMFHNRHLFKDKV 91 Q SSE + + S + V T T + + +L + Sbjct: 227 QKVSSENDRGFQRFLDNVQYKSSGILRYERVFGQGFVSTGGLETTKEFVEK-MNLKPGQK 285 Query: 92 VLDVGSGTGILCMFAAKAGARKVIGIECS-SISDYAVKIVKANKLDHVVTIIKGKVEEVE 150 VLDVG G G + A+ V+GI+ S ++ +A++ +A L V Sbjct: 286 VLDVGCGIGGGDFYMAEKFDVHVVGIDLSVNMISFALE--RAIGLSCSVEFEVADCTTKH 343 Query: 151 LPVEKVDIIISEWMGYCLFYESMLNTVLHARD---------KWLAPDGLIFPDRATLYVT 201 P D+I S +T+LH +D KWL P G + Sbjct: 344 YPDNSFDVIYSR------------DTILHIQDKPALFRTFFKWLKPGGKVLISDY----- 386 Query: 202 AIEDRQYKDYKIHWWENVY--GFDMSCIKDVA--IKEPLVDVVDPKQLVTNACLIKEVDI 257 R K + E + G+D+ ++ +K+ V + + + ++ Sbjct: 387 ---CRSPKTPSAEFSEYIKQRGYDLHDVQAYGQMLKDAGFTDVIAEDRTDQFMQVLKREL 443 Query: 258 YTVKVEDLTFTSPFCLQVKRNDYVHALVAY 287 V+ E F S F + DY + + Sbjct: 444 DRVEKEKEKFISDF----SKEDYDDIVGGW 469 Score = 34.3 bits (77), Expect = 0.097, Method: Composition-based stats. Identities = 29/158 (18%), Positives = 59/158 (37%), Gaps = 14/158 (8%) Query: 49 SKDYYFDSYAHFGIHEEML----KDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILC- 103 K+Y+ + A + ML D + R + ++ K VL++G+G G Sbjct: 12 QKNYWIEHSADLTVEAMMLDSRASDLDKEE--RPEVLSLLPPYEGKSVLELGAGIGRFTG 69 Query: 104 MFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVE--EVELPVEKVDIIIS 161 A KAG +I ++ + + N V + V ++++ +D+I S Sbjct: 70 ELAQKAGE--LIALDFIDNVIKKNESI--NGHYKNVKFMCADVTSPDLKITDGSLDLIFS 125 Query: 162 EWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRATLY 199 W+ + + + W+ G IF + + Sbjct: 126 NWL-LMYLSDKEVELLAERMVGWIKVGGYIFFRESCFH 162 >4P7C-A nrPDB Length = 322 Score = 42.4 bits (98), Expect = 3e-04, Method: Composition-based stats. Identities = 31/143 (21%), Positives = 58/143 (40%), Gaps = 8/143 (5%) Query: 87 FKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKV 146 K K VLDVG G G AGA VIG++ + + + ++ D + + Sbjct: 120 LKGKRVLDVGCGNGYYQWRMLGAGADSVIGVDPNWLFFCQFQAMQRYLPDLPAWHLPFAL 179 Query: 147 EEVELPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPD-----GLIFPDRATLYVT 201 E++ +E D + S MG +S ++ +L +D + L+ P + Sbjct: 180 EDLPANLEGFDTVFS--MGVLYHRKSPIDHLLALKDCLVKGGELVMETLVIPGDVHQVLV 237 Query: 202 AIEDRQYKDYKIHWWENVYGFDM 224 EDR + + + +V ++ Sbjct: 238 P-EDRYAQMRNVWFLPSVPALEL 259 >3A27-A nrPDB Length = 272 Score = 42.0 bits (97), Expect = 5e-04, Method: Composition-based stats. Identities = 31/134 (23%), Positives = 59/134 (44%), Gaps = 15/134 (11%) Query: 88 KDKVVLDVGSGTGILCMFAAK-AGARKVIGIECSSISDYAV-KIVKANKLDHVVTIIKGK 145 +++VV+D+ +G G + AK + + V IE + + + + + +K NKL++V+ I+ Sbjct: 119 ENEVVVDMFAGIGYFTIPLAKYSKPKLVYAIEKNPTAYHYLCENIKLNKLNNVIPILADN 178 Query: 146 VEEVELPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRAT----LYVT 201 +VEL D+ MGY L+ +L G+I +Y Sbjct: 179 -RDVELK----DVADRVIMGYVHKTHKFLDKTFE----FLKDRGVIHYHETVAEKIMYER 229 Query: 202 AIEDRQYKDYKIHW 215 IE ++ K + Sbjct: 230 PIERLKFYAEKNGY 243 >5JE5-A nrPDB Length = 247 Score = 41.6 bits (96), Expect = 5e-04, Method: Composition-based stats. Identities = 30/140 (21%), Positives = 57/140 (40%), Gaps = 6/140 (4%) Query: 54 FDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARK 113 +DS G+ E+ + + ++FH K VLD+ G G + GA K Sbjct: 9 YDSIG--GLFEDFTQSAAQRAIEVRTIFHMIGDVSGKSVLDLACGFGFFGREIYRRGAAK 66 Query: 114 VIGIECSS-ISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYES 172 V+G++ S + + A + ++ K + V +E P+ + D++ + W+ Sbjct: 67 VVGVDISEKMIELARE--ESRKYGDPLEFHVRDVANME-PLGQFDLVNAAWLFNYADSVE 123 Query: 173 MLNTVLHARDKWLAPDGLIF 192 L + L PDG + Sbjct: 124 NLRKMFKVVRASLKPDGKLV 143 >3EGE-A nrPDB Length = 261 Score = 41.2 bits (95), Expect = 6e-04, Method: Composition-based stats. Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 7/84 (8%) Query: 78 NSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDH 137 N++ + +L K V+ D+G+GTG + A G V +E S + + Sbjct: 24 NAIINLLNLPKGSVIADIGAGTGGYSVALANQGL-FVYAVEPSIVMRQQAVV------HP 76 Query: 138 VVTIIKGKVEEVELPVEKVDIIIS 161 V G E + LP + VD +IS Sbjct: 77 QVEWFTGYAENLALPDKSVDGVIS 100 >3D2L-A nrPDB Length = 243 Score = 39.7 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 31/147 (21%), Positives = 60/147 (40%), Gaps = 12/147 (8%) Query: 56 SYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVI 115 +++E+++D + + K + D+G GTG + A V Sbjct: 4 YEQFAYVYDELMQDVPYPEWVAWVLEQ---VEPGKRIADIGCGTGTATLLLADHYE--VT 58 Query: 116 GIECS-SISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDI--IISEWMGYCLFYES 172 G++ S + + A + KA + + V + E+ELP E VD I+ + + Y L E+ Sbjct: 59 GVDLSEEMLEIAQE--KAMETNRHVDFWVQDMRELELP-EPVDAITILCDSLNY-LQTEA 114 Query: 173 MLNTVLHARDKWLAPDGLIFPDRATLY 199 + + + L G + D + Y Sbjct: 115 DVKQTFDSAARLLTDGGKLLFDVHSPY 141 >3BKW-A nrPDB Length = 243 Score = 39.7 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 25/118 (21%), Positives = 51/118 (43%), Gaps = 19/118 (16%) Query: 92 VLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVEL 151 ++D+G G G C +A + GA V+G++ +S+ + +A D +T + ++++ L Sbjct: 47 IVDLGCGFGWFCRWAHEHGASYVLGLD---LSEKMLARARAAGPDTGITYERADLDKLHL 103 Query: 152 PVEKVDIIISEWMGYCLFYESMLNTVLHARDKW------LAPDG-LIFPDRATLYVTA 202 P + D+ S L+ V + L+P G +F +Y+ Sbjct: 104 PQDSFDLAYSSL---------ALHYVEDVARLFRTVHQALSPGGHFVFSTEHPIYMAP 152 >2YXD-A nrPDB Length = 183 Score = 39.3 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 23/65 (35%), Positives = 35/65 (53%), Gaps = 7/65 (10%) Query: 88 KDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVT---IIKG 144 KD VV+DVG G+G + + AK + V I+ D A+++ K N + IIKG Sbjct: 35 KDDVVVDVGCGSGGMTVEIAK-RCKFVYAID---YLDGAIEVTKQNLAKFNIKNCQIIKG 90 Query: 145 KVEEV 149 + E+V Sbjct: 91 RAEDV 95 >5YAC-A nrPDB Length = 346 Score = 39.3 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 23/78 (29%), Positives = 40/78 (51%), Gaps = 6/78 (7%) Query: 84 RHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSIS-DYAVKIVKANKLDHVVTII 142 + + +VV D+ +G G + AK A V + + + Y + +K NK+++VV I+ Sbjct: 194 KMAQEGEVVFDMFAGVGPFSILLAK-KAELVFACDINPWAIKYLEENIKLNKVNNVVPIL 252 Query: 143 KGKVEEVELPVEKVDIII 160 G E+E+ K D II Sbjct: 253 -GDSREIEV---KADRII 266 >4PNE-A nrPDB Length = 302 Score = 39.3 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 24/101 (23%), Positives = 38/101 (37%), Gaps = 4/101 (3%) Query: 92 VLDVGSGTGILCMFAAKAGARKVIGIECSSISD-YAVKIVKANKLDHVVTIIKGKVEEVE 150 +LDVG GTG + A+ A ++ GI S + A + L H V + Sbjct: 96 LLDVGCGTGQPALRVARDNAIQITGITVSQVQVAIAADCARERGLSHRVDFSCVDAMSLP 155 Query: 151 LPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLI 191 P D + W L S + + + L P G++ Sbjct: 156 YPDNAFD---AAWAMQSLLEMSEPDRAIREILRVLKPGGIL 193 >4KDR-A nrPDB Length = 223 Score = 38.9 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 26/107 (24%), Positives = 47/107 (43%), Gaps = 10/107 (9%) Query: 89 DKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTI--IKGKV 146 K VLDVG G GIL A+ GA + + +++ K + L+ + + ++ V Sbjct: 63 GKKVLDVGCGGGILAESMAREGA----TVTGLDMGFEPLQVAKLHALESGIQVDYVQETV 118 Query: 147 EEVELPVE-KVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIF 192 EE + D++ M L + +V+ A + + P G +F Sbjct: 119 EEHAAKHAGQYDVVTCMEM---LEHVPDPQSVVRACAQLVKPGGDVF 162 >4KDC-A nrPDB Length = 246 Score = 38.9 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 26/107 (24%), Positives = 47/107 (43%), Gaps = 10/107 (9%) Query: 89 DKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTI--IKGKV 146 K VLDVG G GIL A+ GA + + +++ K + L+ + + ++ V Sbjct: 63 GKKVLDVGCGGGILAESMAREGA----TVTGLDMGFEPLQVAKLHALESGIQVDYVQETV 118 Query: 147 EEVELPVE-KVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIF 192 EE + D++ M L + +V+ A + + P G +F Sbjct: 119 EEHAAKHAGQYDVVTCMEM---LEHVPDPQSVVRACAQLVKPGGDVF 162 >4QNV-A nrPDB Length = 323 Score = 38.9 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 28/137 (20%), Positives = 54/137 (39%), Gaps = 6/137 (4%) Query: 58 AHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGI 117 F ++ + E R+ + + + + +LDVG G+G AGA +GI Sbjct: 92 GPFSLYGVNIDTEWRSDWKWDRVLPHLSDLTGRTILDVGCGSGYHMWRMIGAGAHLAVGI 151 Query: 118 ECSSISDYAVKIVK-ANKLDHVVTIIKGKVEEVELPVEKV-DIIISEWMGYCLFYESMLN 175 + + + + V+ D ++ +E +LP K D + S MG S L Sbjct: 152 DPTQLFLCQFEAVRKLLGNDQRAHLLPLGIE--QLPALKAFDTVFS--MGVLYHRRSPLE 207 Query: 176 TVLHARDKWLAPDGLIF 192 + +D+ + L+ Sbjct: 208 HLWQLKDQLVNEGELVL 224 >2AVN-A nrPDB Length = 260 Score = 38.5 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 28/148 (18%), Positives = 56/148 (37%), Gaps = 11/148 (7%) Query: 54 FDSYAHFGIHEEMLKDEVRTLTYRNSM--FHNRHLFKDKVVLDVGSGTGILCMFAAKAGA 111 ++ Y + + + + Y + F +L VLD+G GTG +F + G Sbjct: 18 WEFYDRIARAYDSMYETPKWKLYHRLIGSFLEEYLKNPCRVLDLGGGTGKWSLFLQERGF 77 Query: 112 RKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYE 171 V+ + + A + N +++ K E++ P + +++ +G L Y Sbjct: 78 EVVLVDPSKEMLEVAREKGVKN-------VVEAKAEDLPFPSGAFEAVLA--LGDVLSYV 128 Query: 172 SMLNTVLHARDKWLAPDGLIFPDRATLY 199 + + L PDGL+ Y Sbjct: 129 ENKDKAFSEIRRVLVPDGLLIATVDNFY 156 >4FS8-A nrPDB Length = 383 Score = 38.5 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 49/217 (22%), Positives = 82/217 (37%), Gaps = 37/217 (17%) Query: 67 LKDEVRTLTYR-NSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGAR--KVIGIECSSI- 122 + DEV Y S + VLD+G GTG A+K KVIG++ Sbjct: 61 IADEVLEKFYGCGSTLPADGSLEGATVLDLGCGTGRDVYLASKLVGEHGKVIGVDMLDNQ 120 Query: 123 SDYAVKIVKA-------NKLDHVVTIIKGKVEEVE------LPVEKVDIIISEWMGYCLF 169 + A K V+ + V +KG +E + +P VDI+IS + C Sbjct: 121 LEVARKYVEYHAEKFFGSPSRSNVRFLKGFIENLATAEPEGVPDSSVDIVISNCV--CNL 178 Query: 170 YESMLNTVLHARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKD 229 + L + L G ++ + +Y DR+ + +YG C+ Sbjct: 179 STNKLALFKEIH-RVLRDGGELY--FSDVYA----DRRLSEAAQQD-PILYG---ECLGG 227 Query: 230 VAIKEPLVDVVDPKQLVTNACLIKEVDIYTVKVEDLT 266 E D ++LV A ++V + +V D++ Sbjct: 228 ALYLE------DFRRLVAEA-GFRDVRLVSVGPVDVS 257 >5FAD-A nrPDB Length = 161 Score = 38.5 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 23/121 (19%), Positives = 50/121 (41%), Gaps = 10/121 (8%) Query: 80 MFHNRHLFKDKVVLDVGSGTGILCMFAAKA-GARKVIGIECS-SISDYAVKIVKANKLDH 137 M + +D +V D+G G G + + AAK +K +G+E + A+ ++ N + Sbjct: 20 MLEIAKVSQDDIVYDLGCGDGRIIITAAKDFNVKKAVGVEINDERIREALANIEKNGVTG 79 Query: 138 VVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRAT 197 +I+KG EV++ + ++ ++ + +K L P + Sbjct: 80 RASIVKGNFFEVDI--SEATVV------TMFLLTNVNEMLKPKLEKELKPGTRVVSHEFE 131 Query: 198 L 198 + Sbjct: 132 I 132 >1VQ1-A nrPDB Length = 294 Score = 38.1 bits (87), Expect = 0.006, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 37/74 (50%), Gaps = 2/74 (2%) Query: 90 KVVLDVGSGTGILCMFAAKAGARKVIGIECSSIS-DYAVKIVKANKLDHVVTIIKGK-VE 147 K V D+G+G+G + + AK V + SS + + A K + + + + KG+ +E Sbjct: 135 KTVADIGTGSGAIGVSVAKFSDAIVFATDVSSKAVEIARKNAERHGVSDRFFVRKGEFLE 194 Query: 148 EVELPVEKVDIIIS 161 + +++I+S Sbjct: 195 PFKEKFASIEMILS 208 >2PJD-A nrPDB Length = 343 Score = 37.8 bits (86), Expect = 0.007, Method: Composition-based stats. Identities = 28/119 (23%), Positives = 47/119 (39%), Gaps = 12/119 (10%) Query: 86 LFKDKVVLDVGSGTGILCMFAAKAGAR-KVIGIECS-SISDYAVKIVKANKLDHVVTIIK 143 K K VLDVG G G+L + A+ + ++ + S + + + AN ++ V Sbjct: 195 HTKGK-VLDVGCGAGVLSVAFARHSPKIRLTLCDVSAPAVEASRATLAANGVEGEV-FAS 252 Query: 144 GKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRATLYVTA 202 EV+ + D+IIS F++ M T L A + L + A Sbjct: 253 NVFSEVK---GRFDMIISNP----PFHDGM-QTSLDAAQTLIRGAVRHLNSGGELRIVA 303 >1XDU-A nrPDB Length = 374 Score = 37.8 bits (86), Expect = 0.007, Method: Composition-based stats. Identities = 39/172 (22%), Positives = 69/172 (40%), Gaps = 21/172 (12%) Query: 28 LEEVSCGQAESSEKPNA---EDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNR 84 L+ V G+ + + ED+++ DS+ +E L E Y + Sbjct: 127 LDVVRTGRPAYAGRYGRPFWEDLSADVALADSFDALMSCDEDLAYEAPADAY------DW 180 Query: 85 HLFKDKVVLDVGSGTG-ILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIK 143 + VLDVG G G +L A +A + +E + ++ A + L VT+ + Sbjct: 181 SAVRH--VLDVGGGNGGMLAAIALRAPHLRGTLVELAGPAERARRRFADAGLADRVTVAE 238 Query: 144 GKVEEVELPVEKVDIIISEWMGYCLFY---ESMLNTVLHARDKWLAPDGLIF 192 G + LPV D+++ + + L E L T+L + L P G + Sbjct: 239 GDFFK-PLPVT-ADVVL---LSFVLLNWSDEDAL-TILRGCVRALEPGGRLL 284 >3DMF-A nrPDB Length = 381 Score = 37.8 bits (86), Expect = 0.008, Method: Composition-based stats. Identities = 29/110 (26%), Positives = 52/110 (47%), Gaps = 8/110 (7%) Query: 87 FKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVK-IVKANKLDHVVTIIKGK 145 + + VLD+G+G G L + A+ GA V+G+E S +++ ++AN L + Sbjct: 232 VRGRQVLDLGAGYGALTLPLARMGAE-VVGVEDDLASVLSLQKGLEANAL--KAQALHSD 288 Query: 146 VEEVELPVEKVDIIISEW---MGYCLFYESMLNTVLHARDKWLAPDGLIF 192 V+E + DII++ +G + + V A + L P G+ F Sbjct: 289 VDEALTEEARFDIIVTNPPFHVGGAVILDVAQAFVNVAAAR-LRPGGVFF 337 >1I9G-A nrPDB Length = 280 Score = 37.8 bits (86), Expect = 0.008, Method: Composition-based stats. Identities = 29/126 (23%), Positives = 52/126 (41%), Gaps = 17/126 (13%) Query: 80 MFHNRHLFKDKVVLDVGSGTG--ILCMFAAKAGARKVIGIEC-SSISDYAVKIVK--ANK 134 + H +F VL+ G+G+G L + A A +VI E + +++A + V + Sbjct: 91 IVHEGDIFPGARVLEAGAGSGALTLSLLRAVGPAGQVISYEQRADHAEHARRNVSGCYGQ 150 Query: 135 LDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNT--VLHARDKWLAPDGLIF 192 ++ + + ELP VD + + ML VL A + L G++ Sbjct: 151 PPDNWRLVVSDLADSELPDGSVDRAVLD----------MLAPWEVLDAVSRLLVAGGVLM 200 Query: 193 PDRATL 198 AT+ Sbjct: 201 VYVATV 206 >3ELU-A nrPDB Length = 300 Score = 37.8 bits (86), Expect = 0.008, Method: Composition-based stats. Identities = 22/96 (22%), Positives = 41/96 (42%), Gaps = 10/96 (10%) Query: 92 VLDVGSGTGILCMFAAKAGARKVIGIECSSIS-DYAVKIVKANKLDHVVTIIKGKVEEVE 150 VLD+G G G +AA ++V+ ++ ++ + K + L + K K Sbjct: 85 VLDLGCGRGGWSYYAAAQ--KEVMSVKGYTLGIEGHEKPIHMQTLGWNIVKFKDKSNVFT 142 Query: 151 LPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLA 186 +P E D ++ C ES N ++ RD+ + Sbjct: 143 MPTEPSDTLL------CDIGESSSNPLVE-RDRTMK 171 >4HGY-A nrPDB Length = 276 Score = 37.8 bits (86), Expect = 0.009, Method: Composition-based stats. Identities = 22/103 (21%), Positives = 45/103 (43%), Gaps = 3/103 (2%) Query: 92 VLDVGSGTGILCMFAAKAGARKVIGIECS-SISDYAVKIVKANKLDHVVTIIKGKVEEVE 150 VL++G GTG + A G V G+E S + D + A+ ++V + G +++ Sbjct: 66 VLELGVGTGRVAFPLADLGVE-VHGVESSEPMLDKLREKAAAHPNGNLVVPVLGNFAKLD 124 Query: 151 LPVEKVDIIISEWMG-YCLFYESMLNTVLHARDKWLAPDGLIF 192 L ++ ++ + + +CL + + + L P G Sbjct: 125 LGEQRYSVVFAAFNTLFCLLGQDEQIDCMRQARELLEPGGTFV 167 >4KRG-A nrPDB Length = 466 Score = 37.4 bits (85), Expect = 0.010, Method: Composition-based stats. Identities = 26/115 (22%), Positives = 52/115 (45%), Gaps = 4/115 (3%) Query: 77 RNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLD 136 R + + +K V+D+G+G G A+ AR V+ + I + K + N Sbjct: 46 RADILSSLPHLTNKDVVDIGAGIGRFTTVLAET-ARWVLSTDF--IESFIEKNQERNAHM 102 Query: 137 HVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLI 191 ++ G +++ + VD++ + W+ L ++ +L+A +WL DG I Sbjct: 103 GNISYQIGDAVHLQMDEKSVDLVFTNWLMMYLSDREVIEFLLNAM-RWLRADGYI 156 >1DUS-A nrPDB Length = 194 Score = 37.4 bits (85), Expect = 0.010, Method: Composition-based stats. Identities = 30/150 (20%), Positives = 63/150 (42%), Gaps = 22/150 (14%) Query: 78 NSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSI----SDYAVKIVKAN 133 + N + KD +LD+G G G++ + A A +V + I A + +K N Sbjct: 42 KILVENVVVDKDDDILDLGCGYGVIGI----ALADEVKSTTMADINRRAIKLAKENIKLN 97 Query: 134 KLDH-VVTIIKGKV-EEVELPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLI 191 LD+ + ++ + E V+ K + II+ + +L+ ++ + L +G I Sbjct: 98 NLDNYDIRVVHSDLYENVK--DRKYNKIITNP--PIRAGKEVLHRIIEEGKELLKDNGEI 153 Query: 192 FPDRATLYVTAIEDRQYKDYKIHWWENVYG 221 + I+ +Q + ++V+G Sbjct: 154 W--------VVIQTKQGAKSLAKYMKDVFG 175 >3CCF-A nrPDB Length = 279 Score = 37.0 bits (84), Expect = 0.012, Method: Composition-based stats. Identities = 16/86 (18%), Positives = 36/86 (41%), Gaps = 6/86 (6%) Query: 50 KDYYFDSYAHFGIHEEM-----LKDEVRTL-TYRNSMFHNRHLFKDKVVLDVGSGTGILC 103 ++ YF + G + +D+ + Y + + + +LD+G GTG L Sbjct: 13 ENLYFQGMTNLGTAKNFWDATLYQDKHSFVWQYGEDLLQLLNPQPGEFILDLGCGTGQLT 72 Query: 104 MFAAKAGARKVIGIECSSISDYAVKI 129 A++GA + +++ + A + Sbjct: 73 EKIAQSGAEVLGTDNAATMIEKARQN 98 >3MGG-A nrPDB Length = 276 Score = 37.0 bits (84), Expect = 0.014, Method: Composition-based stats. Identities = 30/140 (21%), Positives = 51/140 (36%), Gaps = 12/140 (8%) Query: 57 YAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARK-VI 115 Y H E L+ + T + H+ VL+ G G G + AK + Sbjct: 6 YVHGYSEREALRLSEQAETLEKLLHHDTVYPPGAKVLEAGCGIGAQTVILAKNNPDAEIT 65 Query: 116 GIECSSIS-DYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVD---IIISEWMGYCLFYE 171 I+ S S + A + + N + + V ++ + LP E I + + + E Sbjct: 66 SIDISPESLEKARENTEKNGIKN-VKFLQANI--FSLPFEDSSFDHIFVCFVLEHLQSPE 122 Query: 172 SMLNTVLHARDKWLAPDGLI 191 L ++ K L P G I Sbjct: 123 EALKSL----KKVLKPGGTI 138 >6BQC-A nrPDB Length = 383 Score = 37.0 bits (84), Expect = 0.014, Method: Composition-based stats. Identities = 35/167 (20%), Positives = 62/167 (37%), Gaps = 19/167 (11%) Query: 68 KDEVRTLTYRNS----MFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSIS 123 KD + + + + L VLD+G G G L + A V+G+ S+ Sbjct: 144 KDADNLESAQQAKLKMICEKLQLKPGMRVLDIGCGWGGLAHYMASNYDVSVVGVTISA-E 202 Query: 124 DYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLHARDK 183 + + LD VTI+ ++ ++ D I+S M + +T D+ Sbjct: 203 QQKMAQERCEGLD--VTILLQDYRDLN---DQFDRIVSVGM-FEHVGPKNYDTYFAVVDR 256 Query: 184 WLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDV 230 L P+G +++ + D + W N Y F C+ V Sbjct: 257 NLKPEG--------IFLLHTIGSKKTDLNVDPWINKYIFPNGCLPSV 295 >1KP9-A nrPDB Length = 287 Score = 37.0 bits (84), Expect = 0.014, Method: Composition-based stats. Identities = 25/112 (22%), Positives = 42/112 (37%), Gaps = 7/112 (6%) Query: 88 KDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSI-SDYAVKIVKA-NKLDHVVTIIKGK 145 +LDVG G G M A + V+G+ S +++ ++V L ++ G Sbjct: 64 PGMTLLDVGCGWGATMMRAVEKYDVNVVGLTLSKNQANHVQQLVANSENLRSKRVLLAG- 122 Query: 146 VEEVELPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRAT 197 E E VD I+S + F + + L DG++ T Sbjct: 123 ---WEQFDEPVDRIVS-IGAFEHFGHERYDAFFSLAHRLLPADGVMLLHTIT 170 >5GM1-A nrPDB Length = 297 Score = 36.6 bits (83), Expect = 0.015, Method: Composition-based stats. Identities = 26/127 (20%), Positives = 43/127 (33%), Gaps = 19/127 (14%) Query: 29 EEVSCGQAESSEKPNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFK 88 E V CG + P +DM E + Y + + Sbjct: 34 ESVHCGLWFPPDAPVPQDM----------------ELVTMSSQAQDRYTDYLIETLDPKA 77 Query: 89 DKVVLDVGSGTGILCMFAAKAGARKVIGIECS-SISDYAVKIVKANKLDHVVTIIKGKVE 147 + +LD+G GTG + AA+ V G+ S A ++ + L +T + Sbjct: 78 GQHLLDIGCGTGRTALKAARQRGIAVTGVAVSKEQIAAANRLAAGHGLTERLTF--EVAD 135 Query: 148 EVELPVE 154 + LP E Sbjct: 136 AMRLPYE 142 >2P8J-A nrPDB Length = 209 Score = 36.6 bits (83), Expect = 0.016, Method: Composition-based stats. Identities = 37/149 (24%), Positives = 56/149 (37%), Gaps = 19/149 (12%) Query: 67 LKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGI--LCMFAAKAGARKVIGIECSSI-S 123 +K +R + + DK VLD G+G + L +F K GIE S + Sbjct: 2 MKTIIRQPQLYRFLKYCNESNLDKTVLDCGAGGDLPPLSIFV--EDGYKTYGIEISDLQL 59 Query: 124 DYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLHARD- 182 A + N + I KG + +LP + D +S Y + N V A D Sbjct: 60 KKAENFSRENNF--KLNISKGDIR--KLPFK--DESMSFVYSYGTIFHMRKNDVKEAIDE 113 Query: 183 --KWLAPDGLIFPDRATLYVTAIEDRQYK 209 + L P GL A + +D +Y Sbjct: 114 IKRVLKPGGL-----ACINFLTTKDERYN 137 >5BP9-A nrPDB Length = 281 Score = 36.6 bits (83), Expect = 0.016, Method: Composition-based stats. Identities = 36/164 (21%), Positives = 62/164 (37%), Gaps = 21/164 (12%) Query: 91 VVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDH--VVTIIKGKVEE 148 +LDVG+G+G + A + ++V I+ S +S V+++K + V + + Sbjct: 104 TILDVGAGSGCHAL-ALQESGKEVSAIDISPLS---VEVMKLRGVKDARQVNLFDERF-- 157 Query: 149 VELPVEKVDIIISEWMGYCLFY--ESMLNTVLHARDKWLAPDGLIFPDRATL-YVTAIED 205 D I+ G + E+M + L PDG I D + L Y+ ED Sbjct: 158 ----AATFDTILMLMNGSGIIGRLENM-PLFFRKMKQLLRPDGCILMDSSDLRYLFEDED 212 Query: 206 RQYKDYKIHWWENVYG-FDM-SCIKDVAIKEPLVDVVDPKQLVT 247 + + YG D KD+ +D + L Sbjct: 213 GSFLIDLAG---DYYGEIDFRMQYKDIQGDPFDWLYIDFQTLSA 253 >3GRV-A nrPDB Length = 295 Score = 36.6 bits (83), Expect = 0.017, Method: Composition-based stats. Identities = 28/71 (39%), Positives = 40/71 (56%), Gaps = 5/71 (7%) Query: 82 HNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIEC-SSISDYAVKIVKANKLDHVVT 140 + +L KD VVL++G G GIL AK A+KV IE S+ YA K+ +L + + Sbjct: 44 ESANLTKDDVVLEIGLGKGILTEELAK-NAKKVYVIEIDKSLEPYANKL---KELYNNIE 99 Query: 141 IIKGKVEEVEL 151 II G +V+L Sbjct: 100 IIWGDALKVDL 110 >3FYD-A nrPDB Length = 263 Score = 36.6 bits (83), Expect = 0.017, Method: Composition-based stats. Identities = 28/71 (39%), Positives = 40/71 (56%), Gaps = 5/71 (7%) Query: 82 HNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIEC-SSISDYAVKIVKANKLDHVVT 140 + +L KD VVL++G G GIL AK A+KV IE S+ YA K+ +L + + Sbjct: 15 ESANLTKDDVVLEIGLGKGILTEELAK-NAKKVYVIEIDKSLEPYANKL---KELYNNIE 70 Query: 141 IIKGKVEEVEL 151 II G +V+L Sbjct: 71 IIWGDALKVDL 81 >4O29-A nrPDB Length = 208 Score = 36.2 bits (82), Expect = 0.020, Method: Composition-based stats. Identities = 24/129 (18%), Positives = 50/129 (38%), Gaps = 26/129 (20%) Query: 85 HLFKDKVVLDVGSGTGILCMFAAKAGARK--VIGIE-CSSISDYAVKIVKANKLDHVVTI 141 +L+VG+G+G A+A +K + IE ++ +A + ++ VV + Sbjct: 72 EPRPGMKILEVGTGSGYHAAVCAEAIEKKGRIYTIEIVKELAVFAAQNLERLGYWGVVEV 131 Query: 142 IKGKVE---EVELPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRATL 198 G + E P + II++ + + + A + L G++ Sbjct: 132 YHGDGKKGLEKHAPFD--AIIVT----------AAADVIPPALIRQLKDGGVM------- 172 Query: 199 YVTAIEDRQ 207 V +E+R Sbjct: 173 -VIPVEERL 180 >4IV8-A nrPDB Length = 284 Score = 36.2 bits (82), Expect = 0.025, Method: Composition-based stats. Identities = 41/210 (19%), Positives = 74/210 (35%), Gaps = 28/210 (13%) Query: 80 MFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIE-CSSISDYAVKIVKANKLDHV 138 + + +L + VLD+GSG G C + + V G++ C + A NK Sbjct: 64 ILSDIYLEPNSKVLDIGSGLGGGCKYINEKYDAHVYGVDICEKMIAIAK---LRNKDKSK 120 Query: 139 VTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLHAR-DKWLAPDGLIFPDRAT 197 V + + + P D+I S L L + KWL P+G++ Sbjct: 121 VEFEAMDILKKDFPECTFDMIYSR--DAILHLPYADKKKLFEKCYKWLKPNGILL----- 173 Query: 198 LYVTAIEDRQYKDYKIHWWE-------NVYGFDMSCIKDVA--IKEPLVDVVDPKQLVTN 248 I D Y KI W+ N + + I+D IK V K + Sbjct: 174 -----ITD--YCADKIENWDEEFKAYINKRKYTLIPIQDYGDLIKSCNFQNVQAKDISDY 226 Query: 249 ACLIKEVDIYTVKVEDLTFTSPFCLQVKRN 278 + ++++ ++ + F + + Sbjct: 227 WLELLQMELNKLEEKKDEFLKLYPTDEYNS 256 >1ZQ9-A nrPDB Length = 285 Score = 35.1 bits (79), Expect = 0.050, Method: Composition-based stats. Identities = 20/77 (25%), Positives = 34/77 (44%), Gaps = 2/77 (2%) Query: 78 NSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKI-VKANKLD 136 NS+ L VVL+VG GTG + + A+KV+ E + V+ + Sbjct: 18 NSIIDKAALRPTDVVLEVGPGTGNMTV-KLLEKAKKVVACELDPRLVAELHKRVQGTPVA 76 Query: 137 HVVTIIKGKVEEVELPV 153 + ++ G V + +LP Sbjct: 77 SKLQVLVGDVLKTDLPF 93 >1RI1-A nrPDB Length = 298 Score = 35.1 bits (79), Expect = 0.058, Method: Composition-based stats. Identities = 30/153 (19%), Positives = 57/153 (37%), Gaps = 14/153 (9%) Query: 88 KDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTII----K 143 + VLD+G G G + +AG + G++ + +S V+A + + Sbjct: 64 RGDSVLDLGCGKGGDLLKYERAGIGEYYGVDIAEVS-INDARVRARNMKRRFKVFFRAQD 122 Query: 144 GKVEEVELPVEKVDIIISEWMGYCLFYESM-LNTVLHARDKWLAPDGLIFPDRATLYVTA 202 ++L E D+I S++ + F S L+ + L P G Sbjct: 123 SYGRHMDLGKE-FDVISSQFSFHYAFSTSESLDIAQRNIARHLRPGGYFI------MTVP 175 Query: 203 IEDRQYKDYKIHWWEN-VYGFDMSCIKDVAIKE 234 D + YK N Y ++ ++DV ++ Sbjct: 176 SRDVILERYKQGRMSNDFYKIELEKMEDVPMES 208 >5I2H-A nrPDB Length = 364 Score = 34.7 bits (78), Expect = 0.059, Method: Composition-based stats. Identities = 15/87 (17%), Positives = 33/87 (37%), Gaps = 4/87 (4%) Query: 80 MFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKV-IGIECSSISDYAVKIVKANKLDHV 138 + + +V+LDV G+GI M + I + + A ++ + + Sbjct: 188 ILKDNSGSSGRVLLDVAGGSGIYTMAVLQKYPTWRGIIFDRPEVLKIAAELAEQTGVRDR 247 Query: 139 VTIIKGKVEEVELPVEKV-DIIISEWM 164 + + G + P DI++S + Sbjct: 248 LELHAGDM--WVDPFPPADDILLSNVL 272 >6GKZ-A nrPDB Length = 351 Score = 34.7 bits (78), Expect = 0.059, Method: Composition-based stats. Identities = 24/107 (22%), Positives = 46/107 (42%), Gaps = 9/107 (8%) Query: 89 DKVVLDVGSGTGILCMFAAKAGAR-KVIGI--ECSSISDYAVKIVKANKLDHVVTIIKGK 145 + VLD+G G G L + A+ +V + S + + N L+ V + Sbjct: 124 GQSVLDLGCGQGALTLHVAQKYKNCRVTAVTNSVSQKEYIEEESRRRNLLNVEVKLADIT 183 Query: 146 VEEVELPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIF 192 E+ ++ I++ E + YE +L + +W++ DGL+F Sbjct: 184 THEMAETYDR--ILVIELFEHMKNYELLLRKI----SEWISKDGLLF 224 >5ZW4-A nrPDB Length = 225 Score = 34.7 bits (78), Expect = 0.065, Method: Composition-based stats. Identities = 21/109 (19%), Positives = 45/109 (41%), Gaps = 10/109 (9%) Query: 78 NSMFHNRHLFKDKVVLDVGSGTGILCM-FAAKAGARKVIGIECSSIS-DYAVKIVKANKL 135 + + + K +L++G+ G + A + + ++ IE + + AV +K +L Sbjct: 44 EVLLQILSVKQPKKILEIGTAIGYSAIRMALELPSAEIYTIERNEKRHEEAVNNIKEFQL 103 Query: 136 DHVVTIIKGKVEE------VELPVEK--VDIIISEWMGYCLFYESMLNT 176 D + + G E V P + +D ++ + YE ML+ Sbjct: 104 DDRIHVFYGDALELADAVHVTAPYDVIFIDAAKGQYQNFFHLYEPMLSP 152 >3LGA-A nrPDB Length = 253 Score = 34.7 bits (78), Expect = 0.065, Method: Composition-based stats. Identities = 23/139 (16%), Positives = 52/139 (37%), Gaps = 12/139 (8%) Query: 80 MFHNRHLFKDKVVLDVGSGTGILCMFAAK-AGAR-KVIGIECSS-ISDYAVKIVKANKLD 136 + + +++ G G+G L +F A G +V+ E + A + +K D Sbjct: 85 IVAYAGISPGDFIVEAGVGSGALTLFLANIVGPEGRVVSYEIREDFAKLAWENIKWAGFD 144 Query: 137 HVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRA 196 VTI K++++ +E+ ++ + + V+ K L P G Sbjct: 145 DRVTI---KLKDIYEGIEEENV------DHVILDLPQPERVVEHAAKALKPGGFFVAYTP 195 Query: 197 TLYVTAIEDRQYKDYKIHW 215 + +++K ++ Sbjct: 196 CSNQVMRLHEKLREFKDYF 214 >4MWZ-A nrPDB Length = 267 Score = 34.7 bits (78), Expect = 0.067, Method: Composition-based stats. Identities = 37/210 (17%), Positives = 77/210 (36%), Gaps = 28/210 (13%) Query: 80 MFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIE-CSSISDYAVKIVKANKLDHV 138 + + L + VLD+GSG G C + + V G++ C + A N+ Sbjct: 47 ILSDIQLDANSKVLDIGSGLGGGCKYINEKYGAHVHGVDICEKMVTIAK---LRNQDKAK 103 Query: 139 VTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLHAR-DKWLAPDGLIFPDRAT 197 + + + + P D+I S L +L + KWL P+G++ Sbjct: 104 IEFEAKDILKKDFPESTFDMIYSR--DSILHLSYADKKMLFEKCYKWLKPNGILL----- 156 Query: 198 LYVTAIEDRQYKDYKIHWWENVY-------GFDMSCIKDVA--IKEPLVDVVDPKQLVTN 248 I D Y KI W+ + + + I++ IK V+ K + Sbjct: 157 -----ITD--YCADKIENWDEEFKAYIKKRKYTLMPIQEYGDLIKSCKFQNVEAKDISDY 209 Query: 249 ACLIKEVDIYTVKVEDLTFTSPFCLQVKRN 278 + ++++ ++ + F + ++ + Sbjct: 210 WLELLQLELSKLEEKKEEFLKVYSIKEYNS 239 >1XCL-A nrPDB Length = 235 Score = 34.3 bits (77), Expect = 0.095, Method: Composition-based stats. Identities = 31/141 (21%), Positives = 52/141 (36%), Gaps = 7/141 (4%) Query: 57 YAHFGIHEEMLKDEV--RTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKV 114 Y H ++L V R T + VL+VG G I +A ++ Sbjct: 26 YDTSDTHLQILGKPVMERWETPYMHSLAAAAASRGGRVLEVGFGMAIAASRVQQAPIKEH 85 Query: 115 IGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEV--ELPVEKVDIII--SEWMGYCLFY 170 IEC+ ++ + H V +KG EEV LP D I+ + + ++ Sbjct: 86 WIIECNDGVFQRLQNWALKQ-PHKVVPLKGLWEEVAPTLPDGHFDGILYDTYPLSEETWH 144 Query: 171 ESMLNTVLHARDKWLAPDGLI 191 N + + L P G++ Sbjct: 145 THQFNFIKTHAFRLLKPGGIL 165 >2OXT-A nrPDB Length = 265 Score = 33.9 bits (76), Expect = 0.10, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 32/70 (45%), Gaps = 3/70 (4%) Query: 92 VLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVK-ANKLDHVVTIIKGKVEEVE 150 V+D+G G G +AA V+ + ++ ++ + + K +V+ Sbjct: 78 VVDLGCGRGGWSYYAASR--PHVMDVRAYTLGVGGHEVPRITESYGWNIVKFKSRVDIHT 135 Query: 151 LPVEKVDIII 160 LPVE+ D+I+ Sbjct: 136 LPVERTDVIM 145 >2VS1-A nrPDB Length = 425 Score = 33.9 bits (76), Expect = 0.12, Method: Composition-based stats. Identities = 19/82 (23%), Positives = 39/82 (47%), Gaps = 4/82 (4%) Query: 72 RTLTYR--NSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSIS-DYAVK 128 +T +Y+ N + L + + +LD+ SG G ++ AK G V G + + + + A + Sbjct: 272 QTNSYQAVNLVRKVSELVEGEKILDMYSGVGTFGIYLAKRGFN-VKGFDSNEFAIEMARR 330 Query: 129 IVKANKLDHVVTIIKGKVEEVE 150 V+ N +D + + V+ Sbjct: 331 NVEINNVDAEFEVASDREVSVK 352 >4FGZ-A nrPDB Length = 266 Score = 33.5 bits (75), Expect = 0.13, Method: Composition-based stats. Identities = 33/140 (23%), Positives = 57/140 (40%), Gaps = 19/140 (13%) Query: 80 MFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIE-CSSISDYAVKIVKANKLDHV 138 + + L ++ VLD+GSG G CM+ + GI+ CS+I + A + V N Sbjct: 47 ILSDIELNENSKVLDIGSGLGGGCMYINEKYGAHTHGIDICSNIVNMANERVSGNN---K 103 Query: 139 VTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLHARD-------KWLAPDGLI 191 + + E P D+I S +++L+ L ++ KWL P G + Sbjct: 104 IIFEANDILTKEFPENNFDLIYS--------RDAILHLSLENKNKLFQKCYKWLKPTGTL 155 Query: 192 FPDRATLYVTAIEDRQYKDY 211 D ++K+Y Sbjct: 156 LITDYCATEKENWDDEFKEY 175 >4QPN-A nrPDB Length = 227 Score = 33.5 bits (75), Expect = 0.15, Method: Composition-based stats. Identities = 15/47 (31%), Positives = 25/47 (53%), Gaps = 1/47 (2%) Query: 87 FKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKAN 133 F+ K V+++G+GTGI+ + AA G V + + V+AN Sbjct: 75 FRGKKVIELGAGTGIVGILAALQGGD-VTITDLPLALEQIQGNVQAN 120 >5BXY-A nrPDB Length = 158 Score = 33.5 bits (75), Expect = 0.15, Method: Composition-based stats. Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 3/74 (4%) Query: 80 MFHNRHLFKDKVVLDVGSGTGILCMFAAK-AGARKVIGIECSS-ISDYAVKIVKANKLDH 137 M + + V+ D+GSG G + + AA+ GAR V GIE + A K K + Sbjct: 16 MLELADVDETDVLYDLGSGDGRIVIRAARTHGARGV-GIEIDPDLVKKARKNAKEAGVAD 74 Query: 138 VVTIIKGKVEEVEL 151 +V +G + E ++ Sbjct: 75 LVEFRQGDLFEADI 88 >3HEM-A nrPDB Length = 302 Score = 33.5 bits (75), Expect = 0.17, Method: Composition-based stats. Identities = 38/188 (20%), Positives = 64/188 (34%), Gaps = 14/188 (7%) Query: 20 NGMSLQPPLEEVSCGQAESSEKPN---AEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTY 76 +G L+PP+E V +S+E MT YF+ +M +E + Sbjct: 9 SGTQLKPPVEAVRSHYDKSNEFFKLWLDPSMTYSCAYFERP-------DMTLEEAQYAK- 60 Query: 77 RNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLD 136 R +L +LD+G G G A VIG+ S K + Sbjct: 61 RKLALDKLNLEPGMTLLDIGCGWGSTMRHAVAEYDVNVIGLTLSENQYAHDKAMFDEVDS 120 Query: 137 HVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRA 196 + +++ E E VD I+S + F + + D + + PD Sbjct: 121 PRRKEV--RIQGWEEFDEPVDRIVS-LGAFEHFADGAGDAGFERYDTFFKKFYNLTPDDG 177 Query: 197 TLYVTAIE 204 + + I Sbjct: 178 RMLLHTIT 185 >3BKX-A nrPDB Length = 275 Score = 33.1 bits (74), Expect = 0.21, Method: Composition-based stats. Identities = 13/52 (25%), Positives = 26/52 (50%), Gaps = 2/52 (3%) Query: 72 RTLTYRNSMFHNRHLFKDKVVLDVGSGTGILC-MFAAKAGAR-KVIGIECSS 121 R +R ++ + + +L++G G G L + A + G+ V GI+ +S Sbjct: 27 RQTAHRLAIAEAWQVKPGEKILEIGCGQGDLSAVLADQVGSSGHVTGIDIAS 78 >2YR0-A nrPDB Length = 263 Score = 33.1 bits (74), Expect = 0.21, Method: Composition-based stats. Identities = 23/107 (21%), Positives = 45/107 (42%), Gaps = 9/107 (8%) Query: 88 KDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVE 147 ++ V L++G GTG + + G R + +++ + + K +D V +++ Sbjct: 39 EEPVFLELGVGTGRIALPLIARGYRYIALDADAAMLEVFRQ--KIAGVDRKVQVVQADAR 96 Query: 148 EVELPVEKVD--IIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIF 192 + LP E V I++ W L + VL + L P G + Sbjct: 97 AIPLPDESVHGVIVVHLW---HLVPD--WPKVLAEAIRVLKPGGALL 138 >2YVL-A nrPDB Length = 248 Score = 32.7 bits (73), Expect = 0.23, Method: Composition-based stats. Identities = 20/85 (23%), Positives = 35/85 (41%), Gaps = 7/85 (8%) Query: 70 EVRTLTYRNSMFHNRHLFKDKVVLDVGSGTG-ILCMFAAKAGARKVI-GIECSSISDYAV 127 + Y + +L K+K VL+ G+G+G +L + + AG +E A Sbjct: 76 YPKDSFY---IALKLNLNKEKRVLEFGTGSGALLAVLSEVAGEVWTFEAVE--EFYKTAQ 130 Query: 128 KIVKANKLDHVVTIIKGKVEEVELP 152 K +K L V ++ E+P Sbjct: 131 KNLKKFNLGKNVKFFNVDFKDAEVP 155 >5U19-A nrPDB Length = 341 Score = 32.7 bits (73), Expect = 0.23, Method: Composition-based stats. Identities = 24/110 (21%), Positives = 46/110 (41%), Gaps = 16/110 (14%) Query: 93 LDVGSGTGILCMFAAKAGARKVIGIECSSISD-YAVKIVKANKLDHVVTIIKGKVEEVEL 151 LD+G G+G+L + A V+G++ + + + N L + VT +G + E Sbjct: 148 LDMGCGSGVLSLVLAD-RYESVLGVDVNPRAVALSRLNAALNGLTN-VTFREGDMFE--- 202 Query: 152 PVE-KVDIII---------SEWMGYCLFYESMLNTVLHARDKWLAPDGLI 191 P E + I+ +E++ E +L T + L G++ Sbjct: 203 PAEGRFSRIVFNSPTNEEGNEFVDLLEAGEPILETFFRNVPRKLESGGIV 252 >3BUS-A nrPDB Length = 273 Score = 32.7 bits (73), Expect = 0.27, Method: Composition-based stats. Identities = 25/110 (22%), Positives = 38/110 (34%), Gaps = 6/110 (5%) Query: 48 TSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAA 107 ++ +F + G + R ++ R + VLDVG G G + A Sbjct: 24 WGENLHFGYWEDAGADVSVDDATDRLTDEMIALLDVRSGDR---VLDVGCGIGKPAVRLA 80 Query: 108 KAGARKVIGIECS-SISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKV 156 A +V GI S + A A L + VT + LP E Sbjct: 81 TARDVRVTGISISRPQVNQANARATAAGLANRVTFSYADAMD--LPFEDA 128 >5BP7-A nrPDB Length = 271 Score = 32.7 bits (73), Expect = 0.29, Method: Composition-based stats. Identities = 29/113 (25%), Positives = 45/113 (39%), Gaps = 15/113 (13%) Query: 86 LFKDKVVLDVGSGTG-ILCMFAAKAGARKVIGIECSSISDYAVKIVKAN-KLDHVVTIIK 143 L VLD+GSG+G +LC +A G GI+ S + K+ + VT I Sbjct: 57 LEPGTRVLDLGSGSGEMLCTWARDHGIIG-TGIDMSQLFTAQAKLRAEELGVADRVTFIH 115 Query: 144 GK----VEEVELPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIF 192 G V + + V + + W+G + L + L P G+I Sbjct: 116 GDASGYVSDDKAGV--AACVGATWIGGGVAGTIEL------LARSLRPGGIIL 160 >5H02-A nrPDB Length = 283 Score = 32.4 bits (72), Expect = 0.30, Method: Composition-based stats. Identities = 19/95 (20%), Positives = 37/95 (38%), Gaps = 2/95 (2%) Query: 43 NAEDMTSKDYYFDSY--AHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTG 100 N ++ D Y + Y +E++ E R + +++ + K VLDV +GTG Sbjct: 32 NPIEVRESDGYTNEYVSGFVDKWDELIDWESRAESEGDTIINILKERGVKKVLDVATGTG 91 Query: 101 ILCMFAAKAGARKVIGIECSSISDYAVKIVKANKL 135 + +AG V + + A + + Sbjct: 92 FNSVRLLQAGFDVVSADGSAEMLVKAFDNARDHGY 126 >4HTF-A nrPDB Length = 285 Score = 32.4 bits (72), Expect = 0.30, Method: Composition-based stats. Identities = 24/105 (22%), Positives = 44/105 (41%), Gaps = 12/105 (11%) Query: 92 VLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVEL 151 VLD G G G + A+ G + ++ + + D A + +A + + I ++V Sbjct: 72 VLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVAS 131 Query: 152 PVE-KVDII----ISEWMGYCLFYESMLNTVLHARDKWLAPDGLI 191 +E VD+I + EW+ +VL L P G++ Sbjct: 132 HLETPVDLILFHAVLEWVADP-------RSVLQTLWSVLRPGGVL 169 >6MRO-A nrPDB Length = 194 Score = 32.4 bits (72), Expect = 0.34, Method: Composition-based stats. Identities = 29/120 (24%), Positives = 51/120 (42%), Gaps = 10/120 (8%) Query: 77 RNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLD 136 ++ + + + LD+G G G + AK G V GI+ ++ A+ KA ++ Sbjct: 22 FQALIESGEIRPGRA-LDIGCGRGENAIMLAKNGCD-VTGID---LAKRAISDAKAKAIE 76 Query: 137 HVVTI--IKGKVEEVE--LPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIF 192 V + I G V E++ ++ DI+I + + + E L H K L G F Sbjct: 77 RHVKVNFIVGNVLEMDQLFTEDEFDIVIDSGLFHVITDEERLLFTRHVH-KVLKEGGKYF 135 >5IKM-A nrPDB Length = 269 Score = 32.0 bits (71), Expect = 0.39, Method: Composition-based stats. Identities = 26/127 (20%), Positives = 44/127 (34%), Gaps = 18/127 (14%) Query: 73 TLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGI-----------ECSS 121 T R + N + K V+D+G G G + A G +KV + E Sbjct: 62 TAKLRWFVERNLVKPEGK-VIDLGCGRGGWSYYCA--GLKKVTEVKGYTKGGPGHEEPIP 118 Query: 122 ISDYAVKIVKANKLDHVVTIIKGKVEEV--ELPVEKVDIIISEWMGYCLFYESMLNTVLH 179 ++ Y +VK + V I K + + ++ + I E G L M+ L Sbjct: 119 MATYGWNLVKLHSGKDVFFIPPEKCDTLLCDIGESSPNPTIEE--GRTLRVLKMVEPWLR 176 Query: 180 ARDKWLA 186 + Sbjct: 177 GNQFCIK 183 >2I6G-A nrPDB Length = 199 Score = 32.0 bits (71), Expect = 0.43, Method: Composition-based stats. Identities = 24/144 (16%), Positives = 51/144 (35%), Gaps = 20/144 (13%) Query: 49 SKDYYF-DSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAA 107 + YF + Y H ++L + + + LD+G G G ++ A Sbjct: 5 RDENYFTEKYGLTRTHSDVLA-------------AAKVVAPGRT-LDLGCGNGRNSLYLA 50 Query: 108 KAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYC 167 G V + + S ++ +KA + + + + E D I+S + Sbjct: 51 ANGYD-VTAWDKNPASMANLERIKAAEGLDNLQTDLVDLNTLTFDGE-YDFILSTVV--M 106 Query: 168 LFYESM-LNTVLHARDKWLAPDGL 190 +F E+ + ++ + P G Sbjct: 107 MFLEAQTIPGLIANMQRCTKPGGY 130 >1UWV-A nrPDB Length = 433 Score = 32.0 bits (71), Expect = 0.49, Method: Composition-based stats. Identities = 16/62 (25%), Positives = 27/62 (43%), Gaps = 3/62 (4%) Query: 88 KDKVVLDVGSGTGILCMFAAKAGARKVIGIECSS-ISDYAVKIVKANKLDHVVTIIKGKV 146 + VLD+ G G + A A V+G+E + + + + N L + VT + Sbjct: 286 PEDRVLDLFCGMGNFTLPLATQAAS-VVGVEGVPALVEKGQQNARLNGLQN-VTFYHENL 343 Query: 147 EE 148 EE Sbjct: 344 EE 345 >5EHG-A nrPDB Length = 276 Score = 31.6 bits (70), Expect = 0.50, Method: Composition-based stats. Identities = 27/113 (23%), Positives = 46/113 (40%), Gaps = 9/113 (7%) Query: 79 SMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIEC-SSISDYAVKIVKANKLD- 136 + N + + + V+D+G G G + A G +KV + + + V + Sbjct: 65 FVERNMVIPEGR-VIDLGCGRGGWSYYCA--GLKKVTEVRGYTKGGPGHEEPVPMSTYGW 121 Query: 137 HVVTIIKGKVEEVELPVEKVDII---ISEWMGYCLFYESMLNTVLHARDKWLA 186 ++V ++ GK + LP EK D + I E ES VL + WL Sbjct: 122 NIVKLMSGK-DVFYLPPEKCDTLLCDIGESSPSPTVEESRTIRVLKMVEPWLK 173 >3NDI-A nrPDB Length = 416 Score = 31.6 bits (70), Expect = 0.53, Method: Composition-based stats. Identities = 31/166 (18%), Positives = 59/166 (35%), Gaps = 23/166 (13%) Query: 32 SCGQAESSEKPNAEDMTSKDYYFDSYAH--FGIHEEMLKDEVRTLTYRNSMFHNRHLFKD 89 SC + +E+ + M + Y + S H ML D Sbjct: 58 SCEMVQLTEEVPRDLMFHEVYPYHSSGSSVMREHFAMLA---------RDFLATELTGPD 108 Query: 90 KVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKI---VKANKLDHVVTIIKGKV 146 ++++G GI+ +AG R + S ++ A + V+ + + K Sbjct: 109 PFIVEIGCNDGIMLRTIQEAGVRHLGFEPSSGVAAKAREKGIRVRTDFFE------KATA 162 Query: 147 EEVELPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIF 192 ++V ++I + L + + +VL D LAPDG+ Sbjct: 163 DDVRRTEGPANVIYA---ANTLCHIPYVQSVLEGVDALLAPDGVFV 205 >6DCC-A nrPDB Length = 309 Score = 31.6 bits (70), Expect = 0.58, Method: Composition-based stats. Identities = 17/70 (24%), Positives = 32/70 (45%), Gaps = 13/70 (18%) Query: 87 FKDKVVLDVGSGTGILCM-FAAKAGARKVIGIEC-SSISDYAVKIVKANKLDHVVTIIKG 144 F+ + VLD+G G L + A K G +++G++ S + A + ++ Sbjct: 62 FRGRDVLDLGCNVGHLTLSIACKWGPSRMVGLDIDSRLIHSARQNIR-----------HY 110 Query: 145 KVEEVELPVE 154 EE+ LP + Sbjct: 111 LSEELRLPPQ 120 >6C5B-A nrPDB Length = 341 Score = 31.6 bits (70), Expect = 0.58, Method: Composition-based stats. Identities = 25/127 (19%), Positives = 46/127 (36%), Gaps = 13/127 (10%) Query: 44 AEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKD-------KVVLDVG 96 E K++ + + H E D V H D K V+D+G Sbjct: 125 GETAFEKEFGTSYFGYLAKHPE--ADRVFNEAQAGYTKQVAHAVVDAYDFSPFKTVIDIG 182 Query: 97 SGTGIL--CMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVE 154 +G G L + ++ AR ++ + ++ A K + + + G VE+P + Sbjct: 183 AGYGPLLSAILRSQPEARGIL-FDQPHVAQAAGKRLAEAGVGDRCGTVGGDFF-VEVPAD 240 Query: 155 KVDIIIS 161 I+S Sbjct: 241 GDVYILS 247 >6GFK-A nrPDB Length = 251 Score = 31.6 bits (70), Expect = 0.63, Method: Composition-based stats. Identities = 19/87 (21%), Positives = 39/87 (44%), Gaps = 4/87 (4%) Query: 93 LDVGSG-TGILCMFAAKAGARKVIGIECSSIS-DYAVKIVKANKLDHVVTIIKGKVEEV- 149 +D+G+G + I + A + E + +YA K V+ N L ++ ++K + + Sbjct: 67 IDIGTGASCIYPLLGATLNGWYFLATEVDDMCFNYAKKNVEQNNLSDLIKVVKVPQKTLL 126 Query: 150 -ELPVEKVDIIISEWMGYCLFYESMLN 175 + E+ +II M F+ + L Sbjct: 127 MDALKEESEIIYDFCMCNPPFFANQLE 153 >6DU5-A nrPDB Length = 313 Score = 31.6 bits (70), Expect = 0.63, Method: Composition-based stats. Identities = 19/87 (21%), Positives = 39/87 (44%), Gaps = 4/87 (4%) Query: 93 LDVGSG-TGILCMFAAKAGARKVIGIECSSIS-DYAVKIVKANKLDHVVTIIKGKVEEV- 149 +D+G+G + I + A + E + +YA K V+ N L ++ ++K + + Sbjct: 110 IDIGTGASCIYPLLGATLNGWYFLATEVDDMCFNYAKKNVEQNNLSDLIKVVKVPQKTLL 169 Query: 150 -ELPVEKVDIIISEWMGYCLFYESMLN 175 + E+ +II M F+ + L Sbjct: 170 MDALKEESEIIYDFCMCNPPFFANQLE 196 >1ECF-A nrPDB Length = 504 Score = 31.6 bits (70), Expect = 0.64, Method: Composition-based stats. Identities = 18/62 (29%), Positives = 29/62 (46%), Gaps = 6/62 (9%) Query: 66 MLKDEVRTLTYRNSMFHNRHLFKDKVVLDV------GSGTGILCMFAAKAGARKVIGIEC 119 M ++R + R + NR F+DK VL V G+ + + A +AGA+KV Sbjct: 336 MPGQQLRRKSVRRKLNANRAEFRDKNVLLVDDSIVRGTTSEQIIEMAREAGAKKVYLASA 395 Query: 120 SS 121 + Sbjct: 396 AP 397 >4QDJ-A nrPDB Length = 238 Score = 31.2 bits (69), Expect = 0.68, Method: Composition-based stats. Identities = 13/35 (37%), Positives = 17/35 (48%), Gaps = 1/35 (2%) Query: 87 FKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSS 121 +V D G G G L + A+AGA V G + S Sbjct: 61 LPGLLVCDAGCGVGSLSIPLAQAGA-LVYGSDISE 94 >3NJR-A nrPDB Length = 204 Score = 31.2 bits (69), Expect = 0.68, Method: Composition-based stats. Identities = 21/122 (17%), Positives = 41/122 (33%), Gaps = 8/122 (6%) Query: 77 RNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLD 136 R + +++ D+G G+G + + AG R + + + K + L Sbjct: 44 RALTLAALAPRRGELLWDIGGGSGSVSVEWCLAGGRAITIEPRADRIENIQKNIDTYGLS 103 Query: 137 HVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRA 196 + ++G P D+ + E + +WLAP I + Sbjct: 104 PRMRAVQGTA-----PAALADLPLPE---AVFIGGGGSQALYDRLWEWLAPGTRIVANAV 155 Query: 197 TL 198 TL Sbjct: 156 TL 157 >4LEC-A nrPDB Length = 212 Score = 31.2 bits (69), Expect = 0.74, Method: Composition-based stats. Identities = 12/47 (25%), Positives = 25/47 (53%), Gaps = 1/47 (2%) Query: 87 FKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKAN 133 + + +++G+GTG++ + AA GA V + ++ V+AN Sbjct: 58 LRGRSAVELGAGTGLVGIVAALLGA-HVTITDRKVALEFLKSNVQAN 103 >4V0R-A nrPDB Length = 892 Score = 31.2 bits (69), Expect = 0.75, Method: Composition-based stats. Identities = 27/113 (23%), Positives = 46/113 (40%), Gaps = 9/113 (7%) Query: 79 SMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIEC-SSISDYAVKIVKANKLD- 136 + N + + + V+D+G G G + A G +KV + + + V + Sbjct: 62 FVERNMVIPEGR-VIDLGCGRGGWSYYCA--GLKKVTEVRGYTKGGPGHEEPVPMSTYGW 118 Query: 137 HVVTIIKGKVEEVELPVEKVDII---ISEWMGYCLFYESMLNTVLHARDKWLA 186 ++V ++ GK + LP EK D + I E ES VL + WL Sbjct: 119 NIVKLMSGK-DVFYLPPEKCDTLLCDIGESSPSPTVEESRTIRVLKMVEPWLK 170 >2B25-A nrPDB Length = 336 Score = 30.8 bits (68), Expect = 0.88, Method: Composition-based stats. Identities = 16/82 (19%), Positives = 27/82 (32%), Gaps = 13/82 (15%) Query: 78 NSMFHNRHLFKDKVVLDVGSGTGILCMFAAKA--GARKVIGIE--------CSSISDYAV 127 N + + VL+ GSG+G + +F +KA +VI E + Sbjct: 95 NMILSMMDINPGDTVLEAGSGSGGMSLFLSKAVGSQGRVISFEVRKDHHDLAKKNYKHWR 154 Query: 128 KIVKA---NKLDHVVTIIKGKV 146 K + V I + Sbjct: 155 DSWKLSHVEEWPDNVDFIHKDI 176 >6AW7-A nrPDB Length = 228 Score = 30.8 bits (68), Expect = 0.90, Method: Composition-based stats. Identities = 29/154 (18%), Positives = 59/154 (38%), Gaps = 16/154 (10%) Query: 91 VVLDVGSGTGILCMFAAKA---GARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVE 147 +VL++G+ G + A+ GAR + + + +++ L VTI+ G + Sbjct: 61 LVLELGAYCGYSAVRMARLLSPGARLLTMEKNPDYAAITQQMLNFAGLQDKVTILIGASQ 120 Query: 148 EVELPVEKVD------IIISEWMGYCLFYESMLNTV-LHARDKWLAPDGLIFPDRATLYV 200 ++ ++K D + + W L +L L + L D +I P Sbjct: 121 DLIPQLKKYDVDTLDLVFLDHWKDRYLPDTILLEECGLLRKGTVLLADNVIVPGTPDFLA 180 Query: 201 -----TAIEDRQYKDYKIHWWENVYGFDMSCIKD 229 ++ E Y Y + + + V G + + K Sbjct: 181 YVRGSSSFECTHYSSY-LEYMKVVDGLEKAVYKG 213 >2GLU-A nrPDB Length = 239 Score = 30.8 bits (68), Expect = 0.94, Method: Composition-based stats. Identities = 27/152 (17%), Positives = 60/152 (39%), Gaps = 18/152 (11%) Query: 92 VLDVGSGTGILCMFAAKAGARKVIGIEC-SSISDYAVKIVKANKLDHVVTIIKGKVEEVE 150 VLD+G+G G + A ++ IG++ + + A + +++ V +G E + Sbjct: 25 VLDIGAGAGHTAL-AFSPYVQECIGVDATKEMVEVASSFAQEKGVEN-VRFQQGTAESLP 82 Query: 151 LPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIF------P-----DRATLY 199 P + DII Y + S + + + L DG P D + Sbjct: 83 FPDDSFDIITCR---YAAHHFSDVRKAVREVARVLKQDGRFLLVDHYAPEDPVLDEFVNH 139 Query: 200 VTAIEDRQY-KDYKIHWWENVYGFDMSCIKDV 230 + + D + ++ + W+ ++ + +D+ Sbjct: 140 LNRLRDPSHVRESSLSEWQAMFSANQLAYQDI 171 >1R74-A nrPDB Length = 294 Score = 30.8 bits (68), Expect = 0.94, Method: Composition-based stats. Identities = 13/38 (34%), Positives = 20/38 (52%), Gaps = 2/38 (5%) Query: 92 VLDVGSGTGILCMFAAKAGARKVIGIECSS-ISDYAVK 128 VLDV GTG+ + + G V ++ S + YA+K Sbjct: 60 VLDVACGTGVDSIMLVEEGFS-VTSVDASDKMLKYALK 96 >1D2C-A nrPDB Length = 292 Score = 30.8 bits (68), Expect = 0.94, Method: Composition-based stats. Identities = 13/38 (34%), Positives = 20/38 (52%), Gaps = 2/38 (5%) Query: 92 VLDVGSGTGILCMFAAKAGARKVIGIECSS-ISDYAVK 128 VLDV GTG+ + + G V ++ S + YA+K Sbjct: 60 VLDVACGTGVDSIMLVEEGFS-VTSVDASDKMLKYALK 96 >2VN8-A nrPDB Length = 375 Score = 30.8 bits (68), Expect = 0.95, Method: Composition-based stats. Identities = 21/80 (26%), Positives = 32/80 (40%), Gaps = 6/80 (7%) Query: 89 DKVVLDVGS--GTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKV 146 K VL +G+ G G + KA V + S A ++V+ D V+ G V Sbjct: 184 GKRVLILGASGGVGTFAIQVMKAWDAHVTAV----CSQDASELVRKLGADDVIDYKSGSV 239 Query: 147 EEVELPVEKVDIIISEWMGY 166 EE ++ D I+ G Sbjct: 240 EEQLKSLKPFDFILDNVGGS 259 >1KR5-A nrPDB Length = 226 Score = 30.8 bits (68), Expect = 1.0, Method: Composition-based stats. Identities = 38/144 (26%), Positives = 55/144 (38%), Gaps = 13/144 (9%) Query: 53 YFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGIL-CMFAAKAGA 111 Y DS G + Y + ++ K LDVGSG+GIL FA G Sbjct: 45 YMDSPQSIGFQATI--SAPHMHAYALELLFDQLHEGAKA-LDVGSGSGILTACFARMVGC 101 Query: 112 R-KVIGIE-CSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLF 169 KVIGI+ + D +V V+ D + G+ V+L V + +E Y Sbjct: 102 TGKVIGIDHIKELVDDSVNNVRK---DDPTLLSSGR---VQLVVGDGRMGYAEEAPYDAI 155 Query: 170 YESMLNTVL-HARDKWLAPDGLIF 192 + V+ A L P G + Sbjct: 156 HVGAAAPVVPQALIDQLKPGGRLI 179 >2AJB-A nrPDB Length = 728 Score = 30.4 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 17/96 (17%), Positives = 41/96 (42%), Gaps = 16/96 (16%) Query: 120 SSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLH 179 SS SD +++++ N + + +++V++P +K+D+I G +Y+ +L Sbjct: 446 SSSSDKELRVLEDN------SALDKMLQDVQMPSKKLDVI--NLHGTKFWYQMILPPHFD 497 Query: 180 ARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHW 215 K+ P +Y + +++ W Sbjct: 498 KSKKY--------PLLIEVYAGPCSQKVDTVFRLSW 525 >1YUB-A nrPDB Length = 245 Score = 30.4 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 19/79 (24%), Positives = 39/79 (49%), Gaps = 5/79 (6%) Query: 78 NSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIEC-SSISDYAVKIVKANKLD 136 N + +L + V ++G+G G L AK +++V IE S + + + + +K N Sbjct: 19 NQIIKQLNLKETDTVYEIGTGKGHLTTKLAKI-SKQVTSIELDSHLFNLSSEKLKLN--- 74 Query: 137 HVVTIIKGKVEEVELPVEK 155 VT+I + + + P ++ Sbjct: 75 TRVTLIHQDILQFQFPNKQ 93 >1O54-A nrPDB Length = 277 Score = 30.4 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 32/74 (43%), Gaps = 6/74 (8%) Query: 88 KDKVVLDVGSGTGILCMFAAKA--GARKVIGIEC-SSISDYAVKIVKANKLDHVVTIIKG 144 + ++D G G+G +C A+A + KV E + A + L VTI Sbjct: 112 EGDRIIDTGVGSGAMCAVLARAVGSSGKVFAYEKREEFAKLAESNLTKWGLIERVTI--- 168 Query: 145 KVEEVELPVEKVDI 158 KV ++ ++ D+ Sbjct: 169 KVRDISEGFDEKDV 182 >1P1B-A nrPDB Length = 199 Score = 30.4 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 25/104 (24%), Positives = 43/104 (41%), Gaps = 5/104 (4%) Query: 92 VLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEV-- 149 VL+VG G I +A ++ IEC+ ++ + H V +KG EEV Sbjct: 27 VLEVGFGMAIAASRVQQAPIKEHWIIECNDGVFQRLQNWALKQ-PHKVVPLKGLWEEVAP 85 Query: 150 ELPVEKVDIII--SEWMGYCLFYESMLNTVLHARDKWLAPDGLI 191 LP D I+ + + ++ N + + L P G++ Sbjct: 86 TLPDGHFDGILYDTYPLSEETWHTHQFNFIKTHAFRLLKPGGIL 129 >3P9N-A nrPDB Length = 189 Score = 30.4 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 18/63 (28%), Positives = 27/63 (42%), Gaps = 4/63 (6%) Query: 69 DEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIE--CSSISDYA 126 D VR + + R VLD+ +G+G L + A GA V+ +E S + A Sbjct: 27 DRVRESLFN--IVTARRDLTGLAVLDLYAGSGALGLEALSRGAASVLFVESDQRSAAVIA 84 Query: 127 VKI 129 I Sbjct: 85 RNI 87 >3SM3-A nrPDB Length = 235 Score = 30.1 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 15/44 (34%), Positives = 26/44 (59%), Gaps = 2/44 (4%) Query: 80 MFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSIS 123 + HN +L +D +LD+G G+G + + A G V GI+ +S + Sbjct: 23 IIHN-YLQEDDEILDIGCGSGKISLELASKGYS-VTGIDINSEA 64 >2XVM-A nrPDB Length = 199 Score = 30.1 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 19/118 (16%), Positives = 44/118 (37%), Gaps = 4/118 (3%) Query: 73 TLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKA 132 T T+ + + + K LD+G G G ++ A G V + +++S V+ +K+ Sbjct: 18 TRTHSEVLEAVKVVKPGKT-LDLGCGNGRNSLYLAANGYD-VDAWDKNAMSIANVERIKS 75 Query: 133 NKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGL 190 + + + + + D I+S + + ++ + P G Sbjct: 76 IENLDNLHTRVVDLNNLTF-DRQYDFILSTVV-LMFLEAKTIPGLIANMQRCTKPGGY 131 >6M83-A nrPDB Length = 263 Score = 30.1 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 29/133 (21%), Positives = 48/133 (36%), Gaps = 11/133 (8%) Query: 62 IHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSS 121 +H+ KD R + RH K +LDV GTG + A +E Sbjct: 25 VHQGKGKDYHR-EAADLAALVRRHSPKAASLLDVACGTG----MHLRHLADSFGTVEGLE 79 Query: 122 ISDYAVKIVKANKLDHVVTIIKGKVEEVELP--VEKVDIIISEWMGYCLFYESMLNTVLH 179 +S + I + D V+ G + + L V + S L ++ L+ L Sbjct: 80 LSADMLAIARRRNPDAVLH--HGDMRDFSLGRRFSAVTCMFSAI--GHLAGQAELDAALE 135 Query: 180 ARDKWLAPDGLIF 192 + PDG++ Sbjct: 136 RFAAHVLPDGVVV 148 >3C3P-A nrPDB Length = 210 Score = 30.1 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 33/73 (45%), Gaps = 3/73 (4%) Query: 90 KVVLDVGSGTGILCMFAAKAGA--RKVIGIEC-SSISDYAVKIVKANKLDHVVTIIKGKV 146 ++V+ G G G + A+A + +V+ I+ ++A +++ N L V + G Sbjct: 58 QLVVVPGDGLGCASWWFARAISISSRVVMIDPDRDNVEHARRMLHDNGLIDRVELQVGDP 117 Query: 147 EEVELPVEKVDII 159 + +DI+ Sbjct: 118 LGIAAGQRDIDIL 130 >4NEC-A nrPDB Length = 264 Score = 30.1 bits (66), Expect = 1.8, Method: Composition-based stats. Identities = 26/116 (22%), Positives = 42/116 (36%), Gaps = 12/116 (10%) Query: 92 VLDVGSGTGILCMFAAKAGARKVIGIECSSIS-DYAVKIVKANKLDHVVTIIKGKVEEVE 150 VLD G GTG + A G V G++ S + A A L V + ++ Sbjct: 63 VLDAGCGTGEDALHLAGLG-YAVTGLDLSPTAISVARDKADARGLGAVFEV--ADALDLT 119 Query: 151 LPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRATLYVTAIEDR 206 E+ D +I + + + L A + P A ++ +I DR Sbjct: 120 GWEERFDTVIDSGLAHTFEGDR-LRAYATALHRACRPG-------AVAHILSISDR 167 >6H1E-A nrPDB Length = 208 Score = 30.1 bits (66), Expect = 1.8, Method: Composition-based stats. Identities = 20/76 (26%), Positives = 43/76 (56%), Gaps = 7/76 (9%) Query: 90 KVVLDVGSGTGILCMF-AAKAGARKVI-GIECSS-ISDYAVKIVKANKLDHVVTIIKGKV 146 ++ L+VGSG+G++ F A+ G + + + + + ++ + NK+ H+ +I V Sbjct: 41 EICLEVGSGSGVVSAFLASMIGPQALYMCTDINPEAAACTLETARCNKV-HIQPVITDLV 99 Query: 147 EEVELP--VEKVDIII 160 + + LP EKVD+++ Sbjct: 100 KGL-LPRLTEKVDLLV 114 >1NKV-A nrPDB Length = 256 Score = 29.7 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 25/110 (22%), Positives = 44/110 (40%), Gaps = 13/110 (11%) Query: 88 KDKVVLDVGSGTG-ILCMFAAKAGARKVIGIECSSI-SDYAVKIVKANKLDHVVTIIKGK 145 +LD+GSG+G +LC +A G GI+ SS+ + A + + + V I Sbjct: 36 PGTRILDLGSGSGEMLCTWARDHGITG-TGIDMSSLFTAQAKRRAEELGVSERVHFIHND 94 Query: 146 VEEVELPVEKVDI---IISEWMGYCLFYESMLNTVLHARDKWLAPDGLIF 192 + EK D+ + + W+ L + L P G++ Sbjct: 95 AAGY-VANEKCDVAACVGATWIAGGFAGAEEL------LAQSLKPGGIML 137 >4F5V-A nrPDB Length = 584 Score = 29.7 bits (65), Expect = 2.2, Method: Composition-based stats. Identities = 22/139 (15%), Positives = 49/139 (35%), Gaps = 16/139 (11%) Query: 4 AEAANCIMENFVATLANGMSL----QPPLEEVS--CGQAESSEKPNAEDMTSKDYY---- 53 AE C+ E++++ + N + + P E+V+ C ++ +P + + Y Sbjct: 443 AERLPCV-EDYLSVVLNRLCVLHEKTPVSEKVTKCCSESLVDRRPCFSALGPDETYVPKE 501 Query: 54 -----FDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAK 108 F +A E + + + H H D++ VG T +L + Sbjct: 502 FNAETFTFHADICTLPETERKIKKQTALVELVKHKPHATNDQLKTVVGEFTALLDKCCSA 561 Query: 109 AGARKVIGIECSSISDYAV 127 +E + + + Sbjct: 562 EDKEACFAVEGPKLVESSK 580 >5EVJ-A nrPDB Length = 387 Score = 29.7 bits (65), Expect = 2.2, Method: Composition-based stats. Identities = 33/123 (26%), Positives = 54/123 (43%), Gaps = 21/123 (17%) Query: 92 VLDVGSGTGILCMFAAKAGARK--VIGIECSSISDYAVKIVKANKLD--------HVVTI 141 VLD+G+G+G AAK K V G++ + + V I A+ +T Sbjct: 87 VLDLGAGSGRDAYVAAKLVGEKGSVTGVDMTP-AQLEVAISHADAYARDKLGYGKSNMTF 145 Query: 142 IKGKVEEVE---LPVEKVDIIISEWMGYCLFYESMLNT-VLHARDKWLAPDGLIFPDRAT 197 I+G++E ++ L D++IS C+ S VL + LAP G + + Sbjct: 146 IQGEIEYLDRAGLEDSSFDLVIS----NCVINLSPDKARVLSEAYRVLAPGGEM--HFSD 199 Query: 198 LYV 200 +YV Sbjct: 200 VYV 202 >1DL5-A nrPDB Length = 317 Score = 29.7 bits (65), Expect = 2.2, Method: Composition-based stats. Identities = 21/109 (19%), Positives = 48/109 (44%), Gaps = 12/109 (11%) Query: 45 EDMTSKDYYFDSYAHFGIHEEML----KDEVRTLTYRN----SMFHNRHLF-KDKVVLDV 95 ++ +++ SY ++E+++ D T ++F K VL++ Sbjct: 23 LEIPREEFLTKSYPLSYVYEDIVLVSYDDGEEYSTSSQPSLMALFMEWVGLDKGMRVLEI 82 Query: 96 GSGTGI-LCMFAAKAGARK-VIGIECS-SISDYAVKIVKANKLDHVVTI 141 G GTG + + G + V+ +E S I + A + V+ +++V+ + Sbjct: 83 GGGTGYNAAVMSRVVGEKGLVVSVEYSRKICEIAKRNVERLGIENVIFV 131 >3HP7-A nrPDB Length = 291 Score = 29.3 bits (64), Expect = 2.5, Method: Composition-based stats. Identities = 8/36 (22%), Positives = 18/36 (50%) Query: 87 FKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSI 122 +D + +D+G+ TG + GA+ V ++ + Sbjct: 84 VEDMITIDIGASTGGFTDVMLQNGAKLVYAVDVGTN 119 >3GCZ-A nrPDB Length = 282 Score = 29.3 bits (64), Expect = 2.8, Method: Composition-based stats. Identities = 20/109 (18%), Positives = 38/109 (34%), Gaps = 20/109 (18%) Query: 91 VVLDVGSGTGILCMFAAKAG-ARKVIGI------ECSSISDYAVK--IVKANKLDHV--V 139 +V+D+G G G +AA +KV+ I + +++ V + Sbjct: 93 IVVDLGCGRGGWSYYAASLKNVKKVMAFTLGVQGHEKPIMRTTLGWNLIRFKDKTDVFNM 152 Query: 140 TIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPD 188 +I G ++ I + E + L VL+ +WL Sbjct: 153 EVIPGDTLLCDIGESSPSIAVEE--------QRTLR-VLNCAKQWLQEG 192 >2O5R-A nrPDB Length = 481 Score = 29.3 bits (64), Expect = 3.1, Method: Composition-based stats. Identities = 22/135 (16%), Positives = 49/135 (36%), Gaps = 16/135 (11%) Query: 203 IEDRQYKDYKIHWWENVYGFDMSCIKDVAIKEPLVDVVDPKQLVTNACLIKEVD---IYT 259 + + + W + G ++ ++++ I +D + P + + +K ++ + Sbjct: 281 LPEALVNYLALLGWSHPEGKELLTLEEL-ISSFSLDRLSPNPAIFDPQKLKWMNGYYLRN 339 Query: 260 VKVEDL-TFTSPFCLQVKRNDYVHALVAYFNIEFTRCHKRTG-FSTSPESPYTHWKQTVF 317 + +E L PF ++ YF +R S PE + F Sbjct: 340 MPIEKLAELAKPF---FEKAGIKIIDEEYFKKVLEITKERVEVLSEFPEE-------SRF 389 Query: 318 YMEDYLTVKTGEEIF 332 + ED V+ EE+ Sbjct: 390 FFEDPAPVEIPEEMK 404 >2B3T-A nrPDB Length = 276 Score = 28.9 bits (63), Expect = 3.3, Method: Composition-based stats. Identities = 16/105 (15%), Positives = 40/105 (38%), Gaps = 20/105 (19%) Query: 92 VLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVEL 151 +LD+G+GTG + + A +I+ +++ V++ + + L Sbjct: 113 ILDLGTGTGAIALALASERPD--------------CEIIAVDRMPDAVSLAQRNAQ--HL 156 Query: 152 PVEKVDIIISEWMGYCLFYESML----NTVLHARDKWLAPDGLIF 192 ++ + I+ S+W + + + +D L + F Sbjct: 157 AIKNIHILQSDWFSALAGQQFAMIVSNPPYIDEQDPHLQQGDVRF 201 >4AZW-A nrPDB Length = 471 Score = 28.9 bits (63), Expect = 3.5, Method: Composition-based stats. Identities = 26/112 (23%), Positives = 42/112 (37%), Gaps = 17/112 (15%) Query: 55 DSYAHFGIHEEMLKDEVR---------TLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMF 105 + Y H E D R T Y N +R L + VLD+G G + Sbjct: 27 EIYQTIFGHPEWDGDAARDCNQRLDLITEQYDNL---SRALGRPLNVLDLGCAQGFFSLS 83 Query: 106 AAKAGARKVIGIE-CSSISDYAVKIVKANK-LDHVVTIIKGKVEEVELPVEK 155 A GA ++GI+ + + + N + G++EEV +E+ Sbjct: 84 LASKGAT-IVGIDFQQENINVCRALAEENPDFAAEFRV--GRIEEVIAALEE 132 >2GS9-A nrPDB Length = 211 Score = 28.9 bits (63), Expect = 3.6, Method: Composition-based stats. Identities = 25/105 (23%), Positives = 47/105 (44%), Gaps = 11/105 (10%) Query: 88 KDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVE 147 + +L+VG+GTG + + + +G+E S + AV +A + T ++ E Sbjct: 36 PGESLLEVGAGTG---YWLRRLPYPQKVGVEPSE-AMLAVGRRRAPE----ATWVRAWGE 87 Query: 148 EVELPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIF 192 + P E D+++ F E + +L AR + L P G + Sbjct: 88 ALPFPGESFDVVL--LFTTLEFVEDVERVLLEAR-RVLRPGGALV 129 >4OIC-B nrPDB Length = 467 Score = 28.9 bits (63), Expect = 3.6, Method: Composition-based stats. Identities = 8/35 (22%), Positives = 16/35 (45%) Query: 109 AGARKVIGIECSSISDYAVKIVKANKLDHVVTIIK 143 AGAR V +EC + + + +++ V + Sbjct: 136 AGARSVFAVECVPLWGHKSICGRRPEMEDAVVAVS 170 >3OPN-A nrPDB Length = 232 Score = 28.9 bits (63), Expect = 3.7, Method: Composition-based stats. Identities = 10/34 (29%), Positives = 16/34 (47%) Query: 89 DKVVLDVGSGTGILCMFAAKAGARKVIGIECSSI 122 K LD+GS TG + GA+ V ++ + Sbjct: 38 GKTCLDIGSSTGGFTDVMLQNGAKLVYALDVGTN 71 >5X4Z-H nrPDB Length = 145 Score = 28.9 bits (63), Expect = 3.8, Method: Composition-based stats. Identities = 16/62 (25%), Positives = 29/62 (46%), Gaps = 3/62 (4%) Query: 12 ENFVATLANGMSLQPPLEEVSCGQAESSEKPNAED-MTSKDYYFDSYAHFGIHEEMLKDE 70 ++ TLAN +SL E+ S ++S P D + DY + + EE +D+ Sbjct: 53 DSLTVTLANSLSLDG--EDESANFSKSWRPPKPTDKSLADDYDYVMFGTVYKFEEGDEDK 110 Query: 71 VR 72 ++ Sbjct: 111 IK 112 >1DOH-A nrPDB Length = 283 Score = 28.9 bits (63), Expect = 3.8, Method: Composition-based stats. Identities = 25/108 (23%), Positives = 41/108 (37%), Gaps = 16/108 (14%) Query: 70 EVRTLTYRNSMF----HNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGI----ECSS 121 + R + +++ + KV L G+G GI A + G R I + Sbjct: 6 QPRGESKYDAIPGPLGPQSASLEGKVALVTGAGRGIGREMAMELGRRGCKVIVNYANSTE 65 Query: 122 ISDYAVKIVKANKLDHV-VTIIKGKVEEVELPVE-------KVDIIIS 161 ++ V +K N D V G VE++ E K+DI+ S Sbjct: 66 SAEEVVAAIKKNGSDAACVKANVGVVEDIVRMFEEAVKIFGKLDIVCS 113 >4AZV-A nrPDB Length = 569 Score = 28.9 bits (63), Expect = 4.1, Method: Composition-based stats. Identities = 26/112 (23%), Positives = 42/112 (37%), Gaps = 17/112 (15%) Query: 55 DSYAHFGIHEEMLKDEVR---------TLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMF 105 + Y H E D R T Y N +R L + VLD+G G + Sbjct: 27 EIYQTIFGHPEWDGDAARDCNQRLDLITEQYDNL---SRALGRPLNVLDLGCAQGFFSLS 83 Query: 106 AAKAGARKVIGIE-CSSISDYAVKIVKANK-LDHVVTIIKGKVEEVELPVEK 155 A GA ++GI+ + + + N + G++EEV +E+ Sbjct: 84 LASKGAT-IVGIDFQQENINVCRALAEENPDFAAEFRV--GRIEEVIAALEE 132 >2H1R-A nrPDB Length = 299 Score = 28.9 bits (63), Expect = 4.1, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 33/77 (42%), Gaps = 4/77 (5%) Query: 78 NSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIEC-SSISDYAVKIVKANKLD 136 ++ + D +VL++G GTG L + A+KVI I+ S + K + Sbjct: 33 KIIYAAKIKSSD-IVLEIGCGTGNLTVKLLPL-AKKVITIDIDSRMISEVKKRCLYEGYN 90 Query: 137 HVVTIIKGKVEEVELPV 153 + + + +G + P Sbjct: 91 N-LEVYEGDAIKTVFPK 106 >4OA5-A nrPDB Length = 227 Score = 28.5 bits (62), Expect = 4.3, Method: Composition-based stats. Identities = 13/58 (22%), Positives = 26/58 (44%), Gaps = 3/58 (5%) Query: 92 VLDVGSGTGILCMFAAKAGARK--VIGIECS-SISDYAVKIVKANKLDHVVTIIKGKV 146 +++VG+ G + A A K + IE A + + KL+ +T++ G+ Sbjct: 69 IVEVGTCVGFSAICMAHALPSKGHIYTIEKDYENVVTANQNIVNCKLEDKITVLHGEA 126 >3L8D-A nrPDB Length = 242 Score = 28.5 bits (62), Expect = 4.4, Method: Composition-based stats. Identities = 31/143 (21%), Positives = 56/143 (39%), Gaps = 24/143 (16%) Query: 88 KDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVE 147 K+ VLDVG G G ++ G + V IS+ ++ K ++ IKG + Sbjct: 53 KEAEVLDVGCGDGYGTYKLSRTGYKAV----GVDISEVMIQKGKERGEGPDLSFIKGDLS 108 Query: 148 EVELPVEKVDIIIS----EWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRATLYVTAI 203 + E+ + I++ EW L LN + + L DG A + + Sbjct: 109 SLPFENEQFEAIMAINSLEWTEEPL---RALNEI----KRVLKSDGY-----ACIAILGP 156 Query: 204 EDRQYKDYKIHWWENVYGFDMSC 226 + ++ + +YG D+ C Sbjct: 157 TAKPRENS----YPRLYGKDVVC 175 >5IKP-A nrPDB Length = 846 Score = 28.5 bits (62), Expect = 4.5, Method: Composition-based stats. Identities = 16/99 (16%), Positives = 41/99 (41%), Gaps = 4/99 (4%) Query: 24 LQPPLEEVSCGQAESSEKPNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHN 83 L+ ++++S G E +D+ + + D + F +E ++ + + ++ N Sbjct: 742 LKQAVDQISSGFFSPKEPDCFKDIVNMLMHHDRFKVFADYEAYMQCQAQVDQ----LYRN 797 Query: 84 RHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSI 122 + KV+ ++ AR++ G+E S + Sbjct: 798 PKEWTKKVIRNIACSGKFSSDRTITEYAREIWGVEPSDL 836 >3TM5-A nrPDB Length = 373 Score = 28.5 bits (62), Expect = 4.9, Method: Composition-based stats. Identities = 24/87 (27%), Positives = 38/87 (43%), Gaps = 3/87 (3%) Query: 92 VLDVGSGTG-ILCMFAAKAGARKVIGIEC-SSISDYAVKIVKANKLDHVVTIIKGKVEEV 149 VLD G+G IL A + + ++IGIE A A + + I+G ++ Sbjct: 221 VLDPMCGSGTILIELALRRYSGEIIGIEKYRKHLIGAEMNALAAGVLDKIKFIQGDATQL 280 Query: 150 ELPVEKVDIIISEW-MGYCLFYESMLN 175 V+ VD IS G + +SM+ Sbjct: 281 SQYVDSVDFAISNLPYGLKIGKKSMIP 307 >5IJO-H nrPDB Length = 522 Score = 28.5 bits (62), Expect = 5.0, Method: Composition-based stats. Identities = 14/79 (17%), Positives = 36/79 (45%), Gaps = 10/79 (12%) Query: 136 DHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDR 195 +T + +VE+V+L +++D + + + L + L +L ++ + Sbjct: 369 GEKITSLHREVEKVKLDQKRLD----QELDFILSQQKELEDLLSPLEELVKE------QS 418 Query: 196 ATLYVTAIEDRQYKDYKIH 214 T+Y+ ++ + K YK+ Sbjct: 419 GTIYLQHADEEREKTYKLA 437 >3EVC-A nrPDB Length = 277 Score = 28.5 bits (62), Expect = 5.1, Method: Composition-based stats. Identities = 25/109 (22%), Positives = 45/109 (41%), Gaps = 22/109 (20%) Query: 92 VLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVK---IVKANKLDHVVTIIKGKVEE 148 V+D+G G G C +AA ++V G++ ++ + V++ + + K K + Sbjct: 78 VIDLGCGRGGWCYYAAAQ--KEVSGVKGFTLGRDGHEKPMNVQSLGWN--IITFKDKTDI 133 Query: 149 VELPVEKVDIIISEWMGYCLFYESMLNT---------VLHARDKWLAPD 188 L K D ++ C ES ++ VL +KWLA Sbjct: 134 HRLEPVKCDTLL------CDIGESSSSSVTEGERTVRVLDTVEKWLACG 176 >4DCM-A nrPDB Length = 375 Score = 28.5 bits (62), Expect = 5.4, Method: Composition-based stats. Identities = 14/59 (23%), Positives = 30/59 (50%), Gaps = 3/59 (5%) Query: 77 RNSMFHNRHLFKDKVVLDVGSGTGILCM-FAAKAGARKVIGIECSSISDYAVKI-VKAN 133 R M H + ++V D+G G G++ + K KV+ ++ S ++ + ++ V+ N Sbjct: 212 RFFMQHLPENLEGEIV-DLGCGNGVIGLTLLDKNPQAKVVFVDESPMAVASSRLNVETN 269 >4G1P-A nrPDB Length = 487 Score = 28.1 bits (61), Expect = 5.5, Method: Composition-based stats. Identities = 22/110 (20%), Positives = 42/110 (38%), Gaps = 3/110 (2%) Query: 57 YAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIG 116 Y H+ + L+D T ++ + + + K + V D TG L + A K G Sbjct: 100 YGHYDVQPAQLEDGWDTEPFKLVIDEAKGIMKGRGVTD---DTGPLLSWINVVDAFKASG 156 Query: 117 IECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGY 166 E + ++ + + +IK + V+ V I + W+G Sbjct: 157 QEFPVNLVTCFEGMEESGSLKLDELIKKEANGYFKGVDAVCISDNYWLGT 206 >5KPG-A nrPDB Length = 397 Score = 28.1 bits (61), Expect = 5.6, Method: Composition-based stats. Identities = 36/125 (28%), Positives = 53/125 (42%), Gaps = 8/125 (6%) Query: 71 VRTLTYRNSMFHNRHLFKD-KVVLDVGSGTGILCMFAA-KAGARKVIGIECS-SISDYAV 127 + Y ++ R KD + +LD+G G G L + A K KV GI S S ++ + Sbjct: 150 DESEVYMMDLYCERAQIKDGQSILDLGCGHGSLTLHVAQKYRGCKVTGITNSVSQKEFIM 209 Query: 128 KIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAP 187 K L + V II V + E + I + + YE L V W+A Sbjct: 210 DQCKKLDLSN-VEIILEDVTKFETEITYDRIFAVALIEHMKNYELFLKKV----STWIAQ 264 Query: 188 DGLIF 192 DGL+F Sbjct: 265 DGLLF 269 >4MTL-A nrPDB Length = 244 Score = 28.1 bits (61), Expect = 5.6, Method: Composition-based stats. Identities = 9/26 (34%), Positives = 19/26 (73%) Query: 87 FKDKVVLDVGSGTGILCMFAAKAGAR 112 F+D +L++G+G G++ + A+ GA+ Sbjct: 91 FQDAKILEIGAGPGLVSIVASILGAQ 116 >3VC2-A nrPDB Length = 312 Score = 28.1 bits (61), Expect = 5.6, Method: Composition-based stats. Identities = 25/164 (15%), Positives = 48/164 (29%), Gaps = 20/164 (12%) Query: 50 KDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFK----------------DKVVL 93 Y Y + L D + Y + H + D ++ Sbjct: 64 DGLYHHHYGIGPVDRAALGDPEHSE-YEKKVIAELHRLESAQAEFLMDHLGQAGPDDTLV 122 Query: 94 DVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPV 153 D G G G + A + +V G+ S+ + +A +L + ++ P Sbjct: 123 DAGCGRGGSMVMAHRRFGSRVEGVTLSA-AQADFGNRRARELRIDDHVRSRVCNMLDTPF 181 Query: 154 EKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDGLIFPDRAT 197 +K + S W Y L+ + ++L G Sbjct: 182 DKGAVTAS-WNNESTMYVD-LHDLFSEHSRFLKVGGRYVTITGC 223 >3G7U-A nrPDB Length = 376 Score = 28.1 bits (61), Expect = 5.7, Method: Composition-based stats. Identities = 14/57 (24%), Positives = 32/57 (56%), Gaps = 2/57 (3%) Query: 92 VLDVGSGTGILCMFAAKAGARKVIGIE--CSSISDYAVKIVKANKLDHVVTIIKGKV 146 V+D+ SG G L + AA+AG + +E +I+ +A+ ++ + V+++ ++ Sbjct: 5 VIDLFSGVGGLSLGAARAGFDVKMAVEIDQHAINTHAINFPRSLHVQEDVSLLNAEI 61 >1MD6-A nrPDB Length = 154 Score = 28.1 bits (61), Expect = 5.9, Method: Composition-based stats. Identities = 16/82 (19%), Positives = 26/82 (31%), Gaps = 8/82 (9%) Query: 240 VDPKQLVTNACLIKEVDIYTVKVEDLTFTSPFCLQVKRNDYVHALVAYFNIEFTRCHKRT 299 ++P ++ KE +T D+ TS F A +F + Sbjct: 79 LEPVNIMELYLGAKESKSFTFYRRDMGLTSSFESA--------AYPGWFLCTSPEADQPV 130 Query: 300 GFSTSPESPYTHWKQTVFYMED 321 + PE P T FY + Sbjct: 131 RLTQIPEDPAWDAPITDFYFQQ 152 >2FHP-A nrPDB Length = 187 Score = 28.1 bits (61), Expect = 6.4, Method: Composition-based stats. Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 4/65 (6%) Query: 70 EVRTLTYRNSMFHNRHL-FKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVK 128 T + S+F+ F + LD+ SG+G L + A G K I IE + A+K Sbjct: 25 RPTTDKVKESIFNMIGPYFDGGMALDLYSGSGGLAIEAVSRGMDKSICIEKN---FAALK 81 Query: 129 IVKAN 133 ++K N Sbjct: 82 VIKEN 86 >2QT9-A nrPDB Length = 766 Score = 28.1 bits (61), Expect = 6.6, Method: Composition-based stats. Identities = 17/97 (17%), Positives = 44/97 (45%), Gaps = 18/97 (18%) Query: 120 SSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVD-IIISEWMGYCLFYESMLNTVL 178 SS++D +++++ N + + ++ V++P +K+D II++E +Y+ +L Sbjct: 484 SSVNDKGLRVLEDN------SALDKMLQNVQMPSKKLDFIILNE---TKFWYQMILPPHF 534 Query: 179 HARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHW 215 K+ P +Y + ++++W Sbjct: 535 DKSKKY--------PLLLDVYAGPCSQKADTVFRLNW 563 >6IFX-A nrPDB Length = 287 Score = 27.7 bits (60), Expect = 8.8, Method: Composition-based stats. Identities = 19/71 (26%), Positives = 34/71 (47%), Gaps = 7/71 (9%) Query: 78 NSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKA--NKL 135 N + + + + V+++G G G L AK A+KV+ E I + I+K + Sbjct: 38 NRIVDHAEVTEKTGVIEIGPGIGALTEQLAK-RAKKVVAFE---IDQRLLPILKDTLSPY 93 Query: 136 DHVVTIIKGKV 146 ++ VT+I V Sbjct: 94 EN-VTVIHQDV 103 >6IFV-A nrPDB Length = 215 Score = 27.7 bits (60), Expect = 8.8, Method: Composition-based stats. Identities = 19/71 (26%), Positives = 34/71 (47%), Gaps = 7/71 (9%) Query: 78 NSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKA--NKL 135 N + + + + V+++G G G L AK A+KV+ E I + I+K + Sbjct: 38 NRIVDHAEVTEKTGVIEIGPGIGALTEQLAK-RAKKVVAFE---IDQRLLPILKDTLSPY 93 Query: 136 DHVVTIIKGKV 146 ++ VT+I V Sbjct: 94 EN-VTVIHQDV 103 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.313 0.132 0.347 Lambda K H 0.267 0.0405 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,699,725 Number of Sequences: 36641 Number of extensions: 545904 Number of successful extensions: 1919 Number of sequences better than 10.0: 165 Number of HSP's better than 10.0 without gapping: 90 Number of HSP's successfully gapped in prelim test: 131 Number of HSP's that attempted gapping in prelim test: 1703 Number of HSP's gapped (non-prelim): 230 length of query: 371 length of database: 10,336,785 effective HSP length: 99 effective length of query: 272 effective length of database: 6,709,326 effective search space: 1824936672 effective search space used: 1824936672 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.5 bits) S2: 60 (27.7 bits)