BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9HCU5 (417 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5TF2-A nrPDB 799 0.0 5NNZ-B nrPDB 46 4e-05 6HQA-B nrPDB 45 7e-05 5XYI-g nrPDB 44 1e-04 5OPT-p nrPDB 43 2e-04 6EOJ-D nrPDB 42 5e-04 4V6W-Ag nrPDB 41 8e-04 4BTS-AR nrPDB 41 8e-04 6Q8F-A nrPDB 40 0.002 6MZM-G nrPDB 40 0.002 4V7E-Bg nrPDB 40 0.002 5FVM-C nrPDB 40 0.002 4J0W-A nrPDB 40 0.002 6EMK-B nrPDB 40 0.003 6QX9-4B nrPDB 39 0.003 5L9T-R nrPDB 39 0.003 6F3T-A nrPDB 39 0.003 6E29-D nrPDB 39 0.003 5MZH-A nrPDB 39 0.004 4V8M-A7 nrPDB 39 0.004 1VYH-C nrPDB 38 0.008 6HHQ-h nrPDB 38 0.009 5Z56-q nrPDB 37 0.011 4PSX-B nrPDB 37 0.016 3FM0-A nrPDB 37 0.016 4LG8-A nrPDB 37 0.019 5K19-A nrPDB 37 0.022 5WYK-BB nrPDB 37 0.022 5GAN-H nrPDB 36 0.035 6G51-g nrPDB 36 0.040 5G04-R nrPDB 35 0.040 5LCW-Q nrPDB 35 0.042 4GGA-A nrPDB 35 0.043 4N14-A nrPDB 35 0.043 5WLC-LU nrPDB 35 0.070 6QX9-5O nrPDB 34 0.14 5FL8-q nrPDB 33 0.16 5NZU-C nrPDB 33 0.17 5I2T-A nrPDB 33 0.18 5Y1U-A nrPDB 33 0.18 5WLC-LO nrPDB 33 0.20 4G56-B nrPDB 33 0.20 3JRO-A nrPDB 33 0.21 3CFV-B nrPDB 33 0.22 2HES-X nrPDB 33 0.24 3C9C-A nrPDB 33 0.25 2YNP-A nrPDB 33 0.28 5K1B-B nrPDB 33 0.29 3MKQ-A nrPDB 33 0.32 5MC6-j nrPDB 32 0.38 5OQL-d nrPDB 32 0.40 5N4A-A nrPDB 32 0.40 3JRP-A nrPDB 32 0.47 5A9Q-0 nrPDB 32 0.49 4BZK-B nrPDB 32 0.60 3J7Y-U nrPDB 32 0.62 5UZ7-B nrPDB 32 0.67 5A31-R nrPDB 32 0.69 2E1U-A nrPDB 32 0.69 5OQL-X nrPDB 31 0.76 6N9G-C nrPDB 31 0.78 5WLC-LN nrPDB 31 0.84 4BH6-A nrPDB 31 0.91 5OQL-J nrPDB 31 0.97 6IYY-A nrPDB 31 1.0 4J0X-A nrPDB 31 1.2 2AQ5-A nrPDB 30 1.3 5YZG-W nrPDB 30 1.4 3ODT-A nrPDB 30 1.5 3M1Y-A nrPDB 30 1.5 5CXB-B nrPDB 30 1.6 6QDV-o nrPDB 30 1.6 6GMH-W nrPDB 30 1.6 5Y88-O nrPDB 30 1.6 5M25-A nrPDB 30 1.7 5WLC-SG nrPDB 30 1.8 2H9P-A nrPDB 30 1.8 1NR0-A nrPDB 30 1.8 6ELZ-p nrPDB 30 1.9 5OV3-A nrPDB 30 2.3 5BJS-A nrPDB 30 2.6 4AEZ-A nrPDB 29 3.4 5WYJ-BC nrPDB 29 4.0 4XFV-A nrPDB 29 4.1 3JAP-g nrPDB 29 4.2 5A9Q-7 nrPDB 29 4.5 3JB9-L nrPDB 28 5.8 3F3P-A nrPDB 28 6.7 3JZG-A nrPDB 28 6.9 5MWJ-A nrPDB 28 7.5 4XYI-A nrPDB 28 8.0 5K0Y-T nrPDB 28 8.4 5M89-A nrPDB 28 8.9 >5TF2-A nrPDB Length = 407 Score = 799 bits (2063), Expect = 0.0, Method: Compositional matrix adjust. Identities = 389/389 (100%), Positives = 389/389 (100%) Query: 1 MGRRRAPELYRAPFPLYALQVDPSTGLLIAAGGGGAAKTGIKNGVHFLQLELINGRLSAS 60 MGRRRAPELYRAPFPLYALQVDPSTGLLIAAGGGGAAKTGIKNGVHFLQLELINGRLSAS Sbjct: 19 MGRRRAPELYRAPFPLYALQVDPSTGLLIAAGGGGAAKTGIKNGVHFLQLELINGRLSAS 78 Query: 61 LLHSHDTETRATMNLALAGDILAAGQDAHCQLLRFQAHQQQGNKAEKAGSKEQGPRQRKG 120 LLHSHDTETRATMNLALAGDILAAGQDAHCQLLRFQAHQQQGNKAEKAGSKEQGPRQRKG Sbjct: 79 LLHSHDTETRATMNLALAGDILAAGQDAHCQLLRFQAHQQQGNKAEKAGSKEQGPRQRKG 138 Query: 121 AAPAEKKCGAETQHEGLELRVENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRV 180 AAPAEKKCGAETQHEGLELRVENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRV Sbjct: 139 AAPAEKKCGAETQHEGLELRVENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRV 198 Query: 181 WKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQKDQLVTQLHWQENGPTF 240 WKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQKDQLVTQLHWQENGPTF Sbjct: 199 WKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQKDQLVTQLHWQENGPTF 258 Query: 241 SSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGH 300 SSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGH Sbjct: 259 SSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGH 318 Query: 301 EVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEKGRGPE 360 EVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEKGRGPE Sbjct: 319 EVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEKGRGPE 378 Query: 361 LLGSHETALFSVAVDSRCQLHLLPSRRSV 389 LLGSHETALFSVAVDSRCQLHLLPSRRSV Sbjct: 379 LLGSHETALFSVAVDSRCQLHLLPSRRSV 407 >5NNZ-B nrPDB Length = 415 Score = 45.8 bits (107), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 20/64 (31%), Positives = 34/64 (53%), Gaps = 1/64 (1%) Query: 161 CFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK-LVTVGRDLKA 219 CF++ L+AT DG R++ + + + + + HEGEI ++ P G L+T D A Sbjct: 310 CFDYTGKLIATASADGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTA 369 Query: 220 SVWQ 223 +W Sbjct: 370 RIWD 373 Score = 45.4 bits (106), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 57/265 (21%), Positives = 105/265 (39%), Gaps = 59/265 (22%) Query: 158 KVVC--FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDG-KLVTVG 214 ++VC FN +TL+ATG D ++W + + E+V + H EI L+ G +++T Sbjct: 179 EIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGS 238 Query: 215 RDLKASVWQKD--QLVTQL--HWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIP 270 D VW D + V L H E SS + + C +L Sbjct: 239 FDHTVVVWDADTGRKVNILIGHCAE----ISSASFNWD-CSLILTGSMDKTCKL------ 287 Query: 271 HKRLRQPPPCYLTAWDGSNFLPLRTKSCGHE---VVSCLDVSESGTFLGLGTVTGSVAIY 327 WD +N + T + GH+ + SC D +G + + G+ I+ Sbjct: 288 --------------WDATNGKCVATLT-GHDDEILDSCFDY--TGKLIATASADGTARIF 330 Query: 328 IAFSLQCLYYVREAHGIVVTDVAFLP-------------------EKGRGPELLGSHETA 368 A + +C+ + E H ++ ++F P + G+ ++L H Sbjct: 331 SAATRKCIAKL-EGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDE 389 Query: 369 LFSVAVDSRCQLHLLPSR-RSVPVW 392 +FS A + + + + S+ + +W Sbjct: 390 IFSCAFNYKGNIVITGSKDNTCRIW 414 Score = 32.0 bits (71), Expect = 0.51, Method: Compositional matrix adjust. Identities = 17/65 (26%), Positives = 28/65 (43%), Gaps = 1/65 (1%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVG-RDLK 218 + FN L TG +D R+W + + + + H EI A G +V G +D Sbjct: 351 ISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGSKDNT 410 Query: 219 ASVWQ 223 +W+ Sbjct: 411 CRIWR 415 >6HQA-B nrPDB Length = 722 Score = 45.1 bits (105), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 26/71 (36%), Positives = 36/71 (50%), Gaps = 3/71 (4%) Query: 156 LQKVVC--FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK-LVT 212 L V C F+ ++T L TG +D R+W + E V F H G I LA+ PDG+ L + Sbjct: 537 LNDVDCVEFHPNSTYLFTGSSDKTARMWDIARGECVRVFMGHSGAINCLAVSPDGRWLAS 596 Query: 213 VGRDLKASVWQ 223 G D +W Sbjct: 597 AGEDSVVCLWD 607 Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust. Identities = 19/69 (27%), Positives = 31/69 (44%), Gaps = 1/69 (1%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK-LVTVGRDLK 218 V F+ DN L + D VR+W + + ++ +K H + D+ P G T D Sbjct: 459 VDFSPDNRYLISCSEDKTVRLWSLDTYTCLVSYKGHSSSVWDVKFSPMGHYFATASHDQT 518 Query: 219 ASVWQKDQL 227 A +W D + Sbjct: 519 ARLWSCDHI 527 Score = 32.0 bits (71), Expect = 0.49, Method: Compositional matrix adjust. Identities = 34/197 (17%), Positives = 68/197 (34%), Gaps = 45/197 (22%) Query: 162 FNHDNTLLATGGTDGYVRVWKVP-----SLEKVLEFK----------------AHEGEIE 200 FN D+T++A+G D ++++W + SL K + H G + Sbjct: 398 FNDDSTMVASGFQDSFIKLWSIDGSPLRSLLKNDPYNQQNNDGVAVKGSRRLVGHSGAVY 457 Query: 201 DLALGPDGK-LVTVGRDLKASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVP-DQ 258 + PD + L++ D +W D + ++ + + + F DQ Sbjct: 458 GVDFSPDNRYLISCSEDKTVRLWSLDTYTCLVSYKGHSSSVWDVKFSPMGHYFATASHDQ 517 Query: 259 PAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLG 318 A L W + PLR + V C++ + T+L G Sbjct: 518 TARL----------------------WSCDHIYPLRIFAGHLNDVDCVEFHPNSTYLFTG 555 Query: 319 TVTGSVAIYIAFSLQCL 335 + + ++ +C+ Sbjct: 556 SSDKTARMWDIARGECV 572 Score = 30.4 bits (67), Expect = 1.5, Method: Compositional matrix adjust. Identities = 18/61 (29%), Positives = 27/61 (44%), Gaps = 2/61 (3%) Query: 165 DNTLLATGGTDGYVRVWKVPSLEKVLEFKAH-EGEIEDLALGPDGK-LVTVGRDLKASVW 222 D LA+ G D V +W + + ++ + H I LA +G LV+ G D VW Sbjct: 590 DGRWLASAGEDSVVCLWDISTGRRIKAMRGHGRSSIYSLAFSREGTVLVSTGADNSVRVW 649 Query: 223 Q 223 Sbjct: 650 D 650 >5XYI-g nrPDB Length = 335 Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 22/57 (38%), Positives = 33/57 (57%), Gaps = 2/57 (3%) Query: 168 LLATGGTDGYVRVWKVPSLEKVL-EFKAHEGEIEDLALGPDGK-LVTVGRDLKASVW 222 ++A G DG V +W + K++ EFKAH+G + PDGK ++T G D K +W Sbjct: 181 VIAVGCWDGKVYIWSIEKEAKLIKEFKAHDGRCTSVDFTPDGKWVITGGSDRKVVMW 237 Score = 32.0 bits (71), Expect = 0.46, Method: Compositional matrix adjust. Identities = 20/93 (21%), Positives = 42/93 (45%), Gaps = 11/93 (11%) Query: 141 VENLQAVQTDFSSDPLQKVVCFNH---------DNTLLATGGTDGYVRVWKVPSLEKVLE 191 V L Q +++ P +++ NH D + L T D +R+W + + Sbjct: 59 VWKLNRTQEQWAT-PFTRLIGHNHFVSDVSLSRDASHLLTSSWDSTLRLWDLSTRTTKKL 117 Query: 192 FKAHEGEIEDLALGP-DGKLVTVGRDLKASVWQ 223 F H+ ++ + P + ++++VGRD + +W Sbjct: 118 FLGHKKDVLGVTFSPCNRRIISVGRDNQVKIWN 150 >5OPT-p nrPDB Length = 318 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 37/158 (23%), Positives = 66/158 (41%), Gaps = 24/158 (15%) Query: 168 LLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKL-VTVGRDLKASVWQ--K 224 L+ +GG D V+VW + S + + K H I + + PDG L + +D A +W K Sbjct: 168 LIVSGGWDNLVKVWDIASGRLLTDLKGHTNYITSVTVSPDGSLCASSDKDGVARLWDLTK 227 Query: 225 DQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQI----------PHKRL 274 + ++++ +P RY C + G+R+F ++ ++ Sbjct: 228 GEALSEMAAGAPINQICFSPNRYWMCAATE-----KGIRIFDLENKDVIVELAPEAQQKS 282 Query: 275 RQPPPCYLTAW--DGSNFLPLRTKSCGHEVVSCLDVSE 310 ++ P C AW DG+ T + V+ VSE Sbjct: 283 KKTPECMSIAWSADGNTLYSGYTDN----VIRVWSVSE 316 >6EOJ-D nrPDB Length = 470 Score = 42.0 bits (97), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 22/80 (27%), Positives = 41/80 (51%), Gaps = 8/80 (10%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFK-AHEGEIEDLALGP-DGKLVTVGRDLKA 219 ++HD+ + +G DG +++W+ P+ V E AH I D+A D K VT D Sbjct: 143 YSHDSDWMISGDADGMIKIWQ-PNFSMVKEIDAAHTESIRDMAFSSNDSKFVTCSDDNIL 201 Query: 220 SVW-----QKDQLVTQLHWQ 234 +W +++++++ HW Sbjct: 202 KIWNFSNGKQERVLSGHHWD 221 >4V6W-Ag nrPDB Length = 318 Score = 41.2 bits (95), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 5/92 (5%) Query: 163 NHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTV-GRDLKASV 221 NH N ++ + G D V+VW + + + H G + + + PDG L T G+D KA + Sbjct: 160 NHSNPIIVSCGWDRTVKVWNLANCKLKNNHHGHNGYLNTVTVSPDGSLCTSGGKDSKALL 219 Query: 222 WQKD---QLVTQLHWQENGPTFSSTPYRYQAC 250 W + L T H + +P RY C Sbjct: 220 WDLNDGKNLYTLEH-NDIINALCFSPNRYWLC 250 >4BTS-AR nrPDB Length = 343 Score = 41.2 bits (95), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 20/55 (36%), Positives = 32/55 (58%), Gaps = 2/55 (3%) Query: 169 LATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDLKASVW 222 A+ G DG ++VW + + FKAHE + L++ P+GK + T G+D K +W Sbjct: 187 FASVGWDGRLKVWNT-NFQIRYTFKAHESNVNHLSISPNGKYIATGGKDKKLLIW 240 Score = 30.8 bits (68), Expect = 1.0, Method: Compositional matrix adjust. Identities = 38/204 (18%), Positives = 80/204 (39%), Gaps = 28/204 (13%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK-LVTVGRDLK 218 + + +N + D +R+W + + F H+ E+ +A PD + +++ G + + Sbjct: 82 LALSQENCFAISSSWDKTLRLWDLRTGTTYKRFVGHQSEVYSVAFSPDNRQILSAGAERE 141 Query: 219 ASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPP 278 +W ++ + FSS + D + +R + +++ Sbjct: 142 IKLW---NILGECK-------FSSAEKENHS-------DWVSCVRYSPIMKSANKVQPFA 184 Query: 279 PCYLT-AWDG------SNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFS 331 P + + WDG +NF T V+ L +S +G ++ G + I+ + Sbjct: 185 PYFASVGWDGRLKVWNTNFQIRYTFKAHESNVNHLSISPNGKYIATGGKDKKLLIWDILN 244 Query: 332 LQCLYYVREAH-GIVVTDVAFLPE 354 L Y RE G + +AF P+ Sbjct: 245 L--TYPQREFDAGSTINQIAFNPK 266 >6Q8F-A nrPDB Length = 514 Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust. Identities = 18/53 (33%), Positives = 30/53 (56%), Gaps = 1/53 (1%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEF-KAHEGEIEDLALGPDGKLV 211 +CF+ D +LATG DG ++VWK+ S + + F +AH + L+ D + Sbjct: 271 MCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQI 323 Score = 31.6 bits (70), Expect = 0.68, Method: Compositional matrix adjust. Identities = 19/71 (26%), Positives = 36/71 (50%), Gaps = 9/71 (12%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPS--LEKVLEFKAHEG--EIED----LALGPDGKLVTV 213 F+ D L TG DG++ VW + + K L+++A + ++D + D +++ Sbjct: 223 FSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLAT 282 Query: 214 G-RDLKASVWQ 223 G +D K VW+ Sbjct: 283 GAQDGKIKVWK 293 >6MZM-G nrPDB Length = 800 Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust. Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 3/71 (4%) Query: 156 LQKVVC--FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTV 213 L V C F+ ++ +ATG D VR+W V + V F H+G I L P+G+ + Sbjct: 627 LADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLAT 686 Query: 214 G-RDLKASVWQ 223 G D + +W Sbjct: 687 GATDGRVLLWD 697 Score = 36.6 bits (83), Expect = 0.018, Method: Compositional matrix adjust. Identities = 19/67 (28%), Positives = 30/67 (44%), Gaps = 1/67 (1%) Query: 161 CFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDG-KLVTVGRDLKA 219 F+ D L + DG VR+W + + ++ +K H + D P G V+ G D A Sbjct: 550 SFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVA 609 Query: 220 SVWQKDQ 226 +W D Sbjct: 610 RLWATDH 616 Score = 34.7 bits (78), Expect = 0.073, Method: Compositional matrix adjust. Identities = 20/65 (30%), Positives = 30/65 (46%), Gaps = 1/65 (1%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGR-DLK 218 + F+ + LATG TDG V +W + V E K H + L DG+++ G D Sbjct: 675 LTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNT 734 Query: 219 ASVWQ 223 +W Sbjct: 735 VRLWD 739 >4V7E-Bg nrPDB Length = 380 Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust. Identities = 32/111 (28%), Positives = 45/111 (40%), Gaps = 6/111 (5%) Query: 117 QRKGAAPAEKKCGAETQHEGLELRVENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDG 176 QR G + C G +L+V N + + D + P+ V F+ LL G ++G Sbjct: 262 QRFGTGSDDGTCRLFDMRTGHQLQVYNREPDRND-NELPIVTSVAFSISGRLLFAGYSNG 320 Query: 177 YVRVWKVPSLEKVLEF----KAHEGEIEDLALGPDGKLVTVGR-DLKASVW 222 VW E VL +HEG I L L DG + G D +W Sbjct: 321 DCYVWDTLLAEMVLNLGTLQNSHEGRISCLGLSSDGSALCTGSWDKNLKIW 371 Score = 32.7 bits (73), Expect = 0.27, Method: Compositional matrix adjust. Identities = 15/51 (29%), Positives = 24/51 (47%), Gaps = 1/51 (1%) Query: 167 TLLATGGTDGYVRVWKVPSLEK-VLEFKAHEGEIEDLALGPDGKLVTVGRD 216 + +G D VR+W + + V + HEG+I + PDG+ G D Sbjct: 219 NMFISGSCDTTVRLWDLRITSRAVRTYHGHEGDINSVKFFPDGQRFGTGSD 269 >5FVM-C nrPDB Length = 303 Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust. Identities = 21/82 (25%), Positives = 42/82 (51%), Gaps = 4/82 (4%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPD-GKLVTVGRDLK 218 + F +N + + DG ++VW V S +K H + ++A+ P+ G+L++ +D Sbjct: 81 IAFQQENRWMVSSSEDGTIKVWDVRSPSVQRNYK-HNAPVNEVAIHPNQGELISCDQDGN 139 Query: 219 ASVWQ--KDQLVTQLHWQENGP 238 +W ++Q QL ++N P Sbjct: 140 IRIWDLGENQCTNQLTPEDNTP 161 Score = 33.9 bits (76), Expect = 0.12, Method: Compositional matrix adjust. Identities = 42/202 (20%), Positives = 79/202 (39%), Gaps = 26/202 (12%) Query: 5 RAPEL---YRAPFPLYALQVDPSTGLLIAAGGGGAAKTGIKNGVHFLQLELINGRLSASL 61 R+P + Y+ P+ + + P+ G LI+ G +++ + + Sbjct: 105 RSPSVQRNYKHNAPVNEVAIHPNQGELISCDQDGN-----------IRIWDLGENQCTNQ 153 Query: 62 LHSHDTETRATMNLALAGDILAAGQD-AHCQLLRFQAHQQQGNKAEKAGSKEQGPRQRKG 120 L D ++++A G +L AG + +C + R H K + Sbjct: 154 LTPEDNTPLQSLSVASDGSMLVAGNNKGNCYVWRMPHHTDASTLEPVTKFKSHTKYITRV 213 Query: 121 AAPAEKK----CGAETQHEGLELRVENLQAVQTDFSSDPLQKVV---CFNHDNTLLATGG 173 A+ K C A+ H +E+ ++T D Q+ V F+ D+ L T Sbjct: 214 LLSADVKNLATCSAD--HTARVWNIEDNYQLETTL--DGHQRWVWDCAFSADSAYLVTAC 269 Query: 174 TDGYVRVWKVPSLEKVLEFKAH 195 +D YVR+W + + E V ++ H Sbjct: 270 SDHYVRLWDLSTSEIVRQYGGH 291 >4J0W-A nrPDB Length = 343 Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust. Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 8/69 (11%) Query: 154 DPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTV 213 D L + C + GG DG VRVWK+P E L F H+G I+ + L + +V+ Sbjct: 158 DALSRECC-------VTAGGRDGTVRVWKIPE-ESQLVFYGHQGSIDCIHLINEEHMVSG 209 Query: 214 GRDLKASVW 222 D ++W Sbjct: 210 ADDGSVALW 218 >6EMK-B nrPDB Length = 303 Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust. Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 4/75 (5%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPD-GKLVTVGRDLK 218 V F DN + T DG ++VW V S +K H + ++ + P+ G+L++ RD Sbjct: 81 VSFQQDNRWMVTSSEDGTIKVWDVRSPSIPRNYK-HNAPVNEVVIHPNQGELISCDRDGN 139 Query: 219 ASVWQ--KDQLVTQL 231 +W ++Q QL Sbjct: 140 IRIWDLGENQCTHQL 154 Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust. Identities = 12/34 (35%), Positives = 20/34 (58%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAH 195 F+ D+ L T +D YVR+W + + E V ++ H Sbjct: 258 FSADSAYLVTASSDHYVRLWDLSTREIVRQYGGH 291 >6QX9-4B nrPDB Length = 522 Score = 39.3 bits (90), Expect = 0.003, Method: Compositional matrix adjust. Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 1/68 (1%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGR-DLK 218 + F+ D +L TGG D + RVW + + ++ + H EI + P+G + G D Sbjct: 371 IAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNT 430 Query: 219 ASVWQKDQ 226 VW Q Sbjct: 431 CKVWDLRQ 438 Score = 34.3 bits (77), Expect = 0.095, Method: Compositional matrix adjust. Identities = 19/63 (30%), Positives = 29/63 (46%), Gaps = 2/63 (3%) Query: 164 HDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDLKASVW 222 H N LL TG D ++W P + HEG++ L + DG+L+ T D +W Sbjct: 461 HGNFLL-TGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 519 Query: 223 QKD 225 + Sbjct: 520 MAE 522 Score = 33.1 bits (74), Expect = 0.23, Method: Compositional matrix adjust. Identities = 43/207 (20%), Positives = 75/207 (36%), Gaps = 35/207 (16%) Query: 157 QKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGR 215 + V + + LA+ DG V++W + S E V + + H + + P G+ + T Sbjct: 284 KSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCY 343 Query: 216 DLKASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLR 275 D +W + LH + + + G GL F Sbjct: 344 DRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGT-----GGLDAFG--------- 389 Query: 276 QPPPCYLTAWDGSNFLPLRTKSC-----GH-EVVSCLDVSESGTFLGLGTVTGSVAIYIA 329 WD LRT C GH + + ++ S +G + G+ + ++ Sbjct: 390 -------RVWD------LRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDL 436 Query: 330 FSLQCLYYVREAHGIVVTDVAFLPEKG 356 +C+Y + AH +VT V F P G Sbjct: 437 RQRRCVYTI-PAHQNLVTGVKFEPIHG 462 >5L9T-R nrPDB Length = 493 Score = 39.3 bits (90), Expect = 0.003, Method: Compositional matrix adjust. Identities = 19/52 (36%), Positives = 29/52 (55%), Gaps = 1/52 (1%) Query: 164 HDNTLLATGG-TDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVG 214 H N L++T G + + VWK PSL +V + H + LA+ PDG+ + G Sbjct: 410 HANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTG 461 Score = 35.4 bits (80), Expect = 0.042, Method: Compositional matrix adjust. Identities = 22/72 (30%), Positives = 35/72 (48%), Gaps = 12/72 (16%) Query: 147 VQTDFSSDPLQ---------KVVC---FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKA 194 +Q D + PLQ + VC ++ D+ LLA+GG D + VW SL V ++ Sbjct: 294 LQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTE 353 Query: 195 HEGEIEDLALGP 206 H ++ +A P Sbjct: 354 HLAAVKAIAWSP 365 >6F3T-A nrPDB Length = 608 Score = 39.3 bits (90), Expect = 0.003, Method: Compositional matrix adjust. Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 3/71 (4%) Query: 156 LQKVVC--FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTV 213 L V C F+ ++ +ATG D VR+W V + V F H+G I L P+G+ + Sbjct: 435 LADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLAT 494 Query: 214 G-RDLKASVWQ 223 G D + +W Sbjct: 495 GATDGRVLLWD 505 Score = 36.2 bits (82), Expect = 0.024, Method: Compositional matrix adjust. Identities = 19/66 (28%), Positives = 30/66 (45%), Gaps = 1/66 (1%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDG-KLVTVGRDLKAS 220 F+ D L + DG VR+W + + ++ +K H + D P G V+ G D A Sbjct: 359 FSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVAR 418 Query: 221 VWQKDQ 226 +W D Sbjct: 419 LWATDH 424 Score = 34.3 bits (77), Expect = 0.11, Method: Compositional matrix adjust. Identities = 20/65 (30%), Positives = 30/65 (46%), Gaps = 1/65 (1%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGR-DLK 218 + F+ + LATG TDG V +W + V E K H + L DG+++ G D Sbjct: 483 LTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNT 542 Query: 219 ASVWQ 223 +W Sbjct: 543 VRLWD 547 >6E29-D nrPDB Length = 345 Score = 39.3 bits (90), Expect = 0.003, Method: Compositional matrix adjust. Identities = 46/214 (21%), Positives = 81/214 (37%), Gaps = 24/214 (11%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK-LVTVGRDLK 218 V FN LA+G DG V +W + ++ + + H I L+ G+ L++ + K Sbjct: 31 VRFNRKGDFLASGRVDGTVVIWDLETMGVARKLRGHSKNITSLSWSRCGRYLLSACQGWK 90 Query: 219 ASVWQKDQLVTQLHWQENGPTFSS-----TPYRYQACRFGQVP-----DQPAGLRLFTVQ 268 +W + P + + +++ A F P +P +R Sbjct: 91 VILWDLQDGKRYREVRFRAPVYGAELHPWNHHQFAAALFEDQPMLVDITEPVEVRYVLPS 150 Query: 269 IPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYI 328 +P + + P + K + + + + SG L GT G + I Sbjct: 151 VPKRTSTETDPA---------LREKQAKEDAKHMTTAIVYTASGDHLLAGTTKGRLNIID 201 Query: 329 AFSLQCLYYVREAHGIVVTDVAFLPEKGRGPELL 362 A + + +Y + A GI+ T L E GR ELL Sbjct: 202 ARTREIIYSEKIASGIITT--LRLTESGR--ELL 231 >5MZH-A nrPDB Length = 452 Score = 38.9 bits (89), Expect = 0.004, Method: Compositional matrix adjust. Identities = 20/69 (28%), Positives = 33/69 (47%), Gaps = 3/69 (4%) Query: 158 KVVC--FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGR 215 ++VC FN +T++ATG D ++W V + ++ H EI L G L+ G Sbjct: 181 EIVCLSFNPQSTIIATGSMDNTAKLWDVETGQERATLAGHRAEIVSLGFNTGGDLIVTGS 240 Query: 216 -DLKASVWQ 223 D + +W Sbjct: 241 FDHDSRLWD 249 Score = 33.5 bits (75), Expect = 0.17, Method: Compositional matrix adjust. Identities = 18/65 (27%), Positives = 28/65 (43%), Gaps = 1/65 (1%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVG-RDLK 218 V FN T L T +D R+W + E + + H EI A +G + G +D Sbjct: 353 VAFNPQGTRLITASSDKTCRLWDCDTGECLQVLEGHTDEIFSCAFNYEGDFIITGSKDNT 412 Query: 219 ASVWQ 223 +W+ Sbjct: 413 CRIWK 417 Score = 30.8 bits (68), Expect = 1.0, Method: Compositional matrix adjust. Identities = 22/78 (28%), Positives = 33/78 (42%), Gaps = 4/78 (5%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLAL-GPDG-KLVTVGRDLKA 219 FN TG D +VW + E+V + H+ + +A P G K+VT D Sbjct: 102 FNKSGDRFITGSYDRTCKVWNTFTGEEVFTLEGHKNVVYAIAFNNPYGDKIVTGSFDKTC 161 Query: 220 SVWQKDQLVTQLHWQENG 237 +W D QL++ G Sbjct: 162 KLW--DAYTGQLYYTLKG 177 Score = 28.9 bits (63), Expect = 3.8, Method: Compositional matrix adjust. Identities = 44/192 (22%), Positives = 72/192 (37%), Gaps = 39/192 (20%) Query: 169 LATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGR-DLKASVWQKDQL 227 + TG D ++W + + K H+ EI L+ P ++ G D A +W Sbjct: 152 IVTGSFDKTCKLWDAYTGQLYYTLKGHQTEIVCLSFNPQSTIIATGSMDNTAKLWDV--- 208 Query: 228 VTQLHWQENGPTFSSTP-YRYQACRFGQVPDQPAGLRLFTVQIPH-KRLRQPPPCYLTAW 285 E G ++ +R + G G + T H RL W Sbjct: 209 -------ETGQERATLAGHRAEIVSLGF---NTGGDLIVTGSFDHDSRL----------W 248 Query: 286 DGSNFLPLRTKSCGHEV------VSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYVR 339 D +RT C H + VS + +GT + G++ + ++ S +CL V+ Sbjct: 249 D------VRTGQCVHVLSGHRGEVSSTQFNYAGTLVVSGSIDCTSRLWDVRSGRCL-SVK 301 Query: 340 EAHGIVVTDVAF 351 + H V DVAF Sbjct: 302 QGHTDEVLDVAF 313 >4V8M-A7 nrPDB Length = 318 Score = 38.9 bits (89), Expect = 0.004, Method: Compositional matrix adjust. Identities = 25/107 (23%), Positives = 49/107 (45%), Gaps = 8/107 (7%) Query: 165 DNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKL-VTVGRDLKASVWQ 223 D ++ +GG D V+VW + + V + K H + + + PDG L + +D A +W Sbjct: 165 DAPVIVSGGWDNLVKVWDLATGRLVTDLKGHTNYVTSVTVSPDGSLCASSDKDGVARLWD 224 Query: 224 --KDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQ 268 K + ++++ +P RY C + G+R+F ++ Sbjct: 225 LTKGEALSEMAAGAPINQICFSPNRYWMCAATE-----KGIRIFDLE 266 Score = 31.6 bits (70), Expect = 0.68, Method: Compositional matrix adjust. Identities = 32/105 (30%), Positives = 44/105 (41%), Gaps = 13/105 (12%) Query: 138 ELRVENLQAVQTDF-----SSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVP-SLEKVLE 191 LR+ NLQ Q + + D L V F+ DN + +GG D +RVW V L Sbjct: 90 SLRLWNLQNGQCQYKFLGHTKDVLS--VAFSPDNRQIVSGGRDNALRVWNVKGECMHTLS 147 Query: 192 FKAHEGEIEDLALGPDGK---LVTVGRDLKASVWQ--KDQLVTQL 231 AH + + P +V+ G D VW +LVT L Sbjct: 148 RGAHTDWVSCVRFSPSLDAPVIVSGGWDNLVKVWDLATGRLVTDL 192 Score = 30.4 bits (67), Expect = 1.4, Method: Compositional matrix adjust. Identities = 15/65 (23%), Positives = 31/65 (47%), Gaps = 1/65 (1%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK-LVTVGRDLK 218 V +++ + D +R+W + + + +F H ++ +A PD + +V+ GRD Sbjct: 73 VALSNNGNFAVSASWDHSLRLWNLQNGQCQYKFLGHTKDVLSVAFSPDNRQIVSGGRDNA 132 Query: 219 ASVWQ 223 VW Sbjct: 133 LRVWN 137 >1VYH-C nrPDB Length = 410 Score = 37.7 bits (86), Expect = 0.008, Method: Compositional matrix adjust. Identities = 17/72 (23%), Positives = 36/72 (50%), Gaps = 2/72 (2%) Query: 153 SDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK-LV 211 +D +Q + F+H LLA+ D +++W E + H+ + +++ P+G +V Sbjct: 150 TDSVQDI-SFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVSIMPNGDHIV 208 Query: 212 TVGRDLKASVWQ 223 + RD +W+ Sbjct: 209 SASRDKTIKMWE 220 Score = 34.7 bits (78), Expect = 0.070, Method: Compositional matrix adjust. Identities = 16/52 (30%), Positives = 26/52 (50%) Query: 163 NHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVG 214 N D TL+A+ D VRVW V + E E + H +E ++ P+ ++ Sbjct: 243 NQDGTLIASCSNDQTVRVWVVATKECKAELREHRHVVECISWAPESSYSSIS 294 Score = 30.8 bits (68), Expect = 1.2, Method: Compositional matrix adjust. Identities = 34/203 (16%), Positives = 81/203 (39%), Gaps = 28/203 (13%) Query: 155 PLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TV 213 P+ +V+ F+ +++ + D ++VW + + K H ++D++ GKL+ + Sbjct: 110 PVTRVI-FHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASC 168 Query: 214 GRDLKASVW--QKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPH 271 D+ +W Q + + +H ++ V P G + + Sbjct: 169 SADMTIKLWDFQGFECIRTMHGHDHN--------------VSSVSIMPNGDHIVSASRDK 214 Query: 272 KRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFS 331 + W+ ++T + E V + ++ GT + + +V +++ + Sbjct: 215 T---------IKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVAT 265 Query: 332 LQCLYYVREAHGIVVTDVAFLPE 354 +C +RE H VV +++ PE Sbjct: 266 KECKAELRE-HRHVVECISWAPE 287 >6HHQ-h nrPDB Length = 319 Score = 37.7 bits (86), Expect = 0.009, Method: Compositional matrix adjust. Identities = 21/88 (23%), Positives = 40/88 (45%), Gaps = 3/88 (3%) Query: 163 NHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDLKASV 221 + D+ + + G D V+ W + + +F H I L PDG L+ + G+D + + Sbjct: 163 DDDSVTIISAGNDKMVKAWNLNQFQIEADFIGHNSNINTLTASPDGTLIASAGKDGEIML 222 Query: 222 WQ--KDQLVTQLHWQENGPTFSSTPYRY 247 W + + L Q+ + + +P RY Sbjct: 223 WNLAAKKAMYTLSAQDEVFSLAFSPNRY 250 >5Z56-q nrPDB Length = 504 Score = 37.4 bits (85), Expect = 0.011, Method: Compositional matrix adjust. Identities = 18/67 (26%), Positives = 28/67 (41%), Gaps = 1/67 (1%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDG-KLVTVGRDLKAS 220 F+ D + TG D +++W + V F H G I +A +G L T D Sbjct: 358 FHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVK 417 Query: 221 VWQKDQL 227 +W +L Sbjct: 418 LWDLRKL 424 Score = 33.5 bits (75), Expect = 0.17, Method: Compositional matrix adjust. Identities = 16/57 (28%), Positives = 26/57 (45%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRD 216 V F+ L+ + D +R+W VP+ V +AHE + L+L G + D Sbjct: 270 VVFHPSQDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGDYLLSSSD 326 >4PSX-B nrPDB Length = 401 Score = 37.0 bits (84), Expect = 0.016, Method: Compositional matrix adjust. Identities = 23/96 (23%), Positives = 46/96 (47%), Gaps = 7/96 (7%) Query: 139 LRVENLQAVQTDFSS----DPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVL-EFK 193 L++ +++A T + P + +H + LLA G D YV ++ + ++++ L Sbjct: 233 LKINDVRANNTTIDTVKCPQPFNTLAFSHHSSNLLAAAGMDSYVYLYDLRNMKEPLHHMS 292 Query: 194 AHEGEIEDLALGP--DGKLVTVGRDLKASVWQKDQL 227 HE + +L DG +V+ G D + +W Q+ Sbjct: 293 GHEDAVNNLEFSTHVDGVVVSSGSDNRLMMWDLKQI 328 >3FM0-A nrPDB Length = 345 Score = 37.0 bits (84), Expect = 0.016, Method: Compositional matrix adjust. Identities = 20/63 (31%), Positives = 29/63 (46%), Gaps = 3/63 (4%) Query: 167 TLLATGGTDGYVRVWKV--PSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDLKASVWQ 223 LA+ D +WK E V + HE E++ +A P G L+ T RD VW+ Sbjct: 74 NYLASASFDATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWE 133 Query: 224 KDQ 226 D+ Sbjct: 134 VDE 136 Score = 32.0 bits (71), Expect = 0.49, Method: Compositional matrix adjust. Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 8/83 (9%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPS---LEKVLEFKAHEGEIEDLALGPDGK-LVTVGRDL 217 +N TLLA+ G D +R+W + K + + H+ + +A P G L + D Sbjct: 24 WNPAGTLLASCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASFDA 83 Query: 218 KASVWQKDQ----LVTQLHWQEN 236 +W+K+Q VT L EN Sbjct: 84 TTCIWKKNQDDFECVTTLEGHEN 106 >4LG8-A nrPDB Length = 354 Score = 36.6 bits (83), Expect = 0.019, Method: Compositional matrix adjust. Identities = 18/67 (26%), Positives = 28/67 (41%), Gaps = 1/67 (1%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDG-KLVTVGRDLKAS 220 F+ D + TG D +++W + V F H G I +A +G L T D Sbjct: 208 FHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVK 267 Query: 221 VWQKDQL 227 +W +L Sbjct: 268 LWDLRKL 274 Score = 32.3 bits (72), Expect = 0.35, Method: Compositional matrix adjust. Identities = 16/57 (28%), Positives = 26/57 (45%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRD 216 V F+ L+ + D +R+W VP+ V +AHE + L+L G + D Sbjct: 120 VVFHPSQDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGDYLLSSSD 176 >5K19-A nrPDB Length = 569 Score = 36.6 bits (83), Expect = 0.022, Method: Compositional matrix adjust. Identities = 31/111 (27%), Positives = 49/111 (44%), Gaps = 12/111 (10%) Query: 125 EKKCGAETQHEGLELRVEN--LQAVQTDFSSDPLQKVV---------CFNHDNTLLATGG 173 E CG H L + E+ + ++ + +PL K F+ D LA Sbjct: 180 EHTCGTTAPHYQLLKQGESFAVHTCKSKSTRNPLLKWTVGEGALNEFAFSPDGKFLACVS 239 Query: 174 TDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK-LVTVGRDLKASVWQ 223 DG++RV+ S+E K++ G + + PDGK +VT G D +VW Sbjct: 240 QDGFLRVFNFDSVELHGTMKSYFGGLLCVCWSPDGKYIVTGGEDDLVTVWS 290 Score = 30.0 bits (66), Expect = 2.1, Method: Compositional matrix adjust. Identities = 17/66 (25%), Positives = 27/66 (40%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKA 219 VC++ D + TGG D V VW + H+ + +A P V G ++ Sbjct: 268 VCWSPDGKYIVTGGEDDLVTVWSFVDCRVIARGHGHKSWVSVVAFDPYTTSVEEGDPMEF 327 Query: 220 SVWQKD 225 S +D Sbjct: 328 SGSDED 333 >5WYK-BB nrPDB Length = 943 Score = 36.6 bits (83), Expect = 0.022, Method: Compositional matrix adjust. Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 1/60 (1%) Query: 165 DNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLAL-GPDGKLVTVGRDLKASVWQ 223 D LLA G DG ++VW + S +L F H+ I L G +L++ +D VW Sbjct: 90 DTDLLAVGYADGVIKVWDLMSKTVLLNFNGHKAAITLLQFDGTGTRLISGSKDSNIIVWD 149 Score = 33.1 bits (74), Expect = 0.22, Method: Compositional matrix adjust. Identities = 17/57 (29%), Positives = 30/57 (52%), Gaps = 1/57 (1%) Query: 169 LATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQKD 225 L + DG +++W + + + + AH GE LA+ D L+T G D + +W+ D Sbjct: 177 LISTSKDGMIKLWDLKTHQCIETHIAHTGECWGLAV-KDDLLITTGTDSQVKIWKLD 232 Score = 28.9 bits (63), Expect = 4.9, Method: Compositional matrix adjust. Identities = 14/53 (26%), Positives = 26/53 (49%), Gaps = 1/53 (1%) Query: 175 DGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK-LVTVGRDLKASVWQKDQ 226 D V+ W E + + AH+ E+ LA+ DG +V+ D +W++ + Sbjct: 636 DAVVKYWDGEKFECIQKLYAHQSEVWALAVATDGGFVVSSSHDHSIRIWEETE 688 >5GAN-H nrPDB Length = 465 Score = 35.8 bits (81), Expect = 0.035, Method: Compositional matrix adjust. Identities = 20/64 (31%), Positives = 32/64 (50%), Gaps = 1/64 (1%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDG-KLVTVGRDLK 218 + F D +L+ +GG D +W + S KV+ H I +A P+G ++ T G D Sbjct: 313 LSFQCDGSLVCSGGMDSLSMLWDIRSGSKVMTLAGHSKPIYTVAWSPNGYQVATGGGDGI 372 Query: 219 ASVW 222 +VW Sbjct: 373 INVW 376 >6G51-g nrPDB Length = 317 Score = 35.8 bits (81), Expect = 0.040, Method: Compositional matrix adjust. Identities = 23/92 (25%), Positives = 44/92 (47%), Gaps = 5/92 (5%) Query: 163 NHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKL-VTVGRDLKASV 221 N N ++ + G D V+VW + + + H G + + + PDG L + G+D +A + Sbjct: 159 NSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAML 218 Query: 222 WQKDQLVTQLHWQENGPTFSS---TPYRYQAC 250 W ++ L+ + G ++ +P RY C Sbjct: 219 WDLNE-GKHLYTLDGGDIINALCFSPNRYWLC 249 >5G04-R nrPDB Length = 499 Score = 35.4 bits (80), Expect = 0.040, Method: Compositional matrix adjust. Identities = 13/32 (40%), Positives = 18/32 (56%) Query: 180 VWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV 211 +WK P++ KV E K H + L + PDG V Sbjct: 427 IWKYPTMAKVAELKGHTSRVLSLTMSPDGATV 458 >5LCW-Q nrPDB Length = 374 Score = 35.4 bits (80), Expect = 0.042, Method: Compositional matrix adjust. Identities = 13/32 (40%), Positives = 18/32 (56%) Query: 180 VWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV 211 +WK P++ KV E K H + L + PDG V Sbjct: 302 IWKYPTMAKVAELKGHTSRVLSLTMSPDGATV 333 >4GGA-A nrPDB Length = 420 Score = 35.4 bits (80), Expect = 0.043, Method: Compositional matrix adjust. Identities = 13/32 (40%), Positives = 18/32 (56%) Query: 180 VWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV 211 +WK P++ KV E K H + L + PDG V Sbjct: 348 IWKYPTMAKVAELKGHTSRVLSLTMSPDGATV 379 >4N14-A nrPDB Length = 314 Score = 35.4 bits (80), Expect = 0.043, Method: Compositional matrix adjust. Identities = 13/32 (40%), Positives = 18/32 (56%) Query: 180 VWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV 211 +WK P++ KV E K H + L + PDG V Sbjct: 264 IWKYPTMAKVAELKGHTSRVLSLTMSPDGATV 295 >5WLC-LU nrPDB Length = 489 Score = 34.7 bits (78), Expect = 0.070, Method: Compositional matrix adjust. Identities = 13/29 (44%), Positives = 19/29 (65%) Query: 169 LATGGTDGYVRVWKVPSLEKVLEFKAHEG 197 LATG DG ++ W + + E+ + FKAH G Sbjct: 83 LATGSADGVIKYWNMSTREEFVSFKAHYG 111 >6QX9-5O nrPDB Length = 357 Score = 33.9 bits (76), Expect = 0.14, Method: Compositional matrix adjust. Identities = 14/47 (29%), Positives = 23/47 (48%) Query: 165 DNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV 211 D + +A G D +V VW S + + H G I ++A PD ++ Sbjct: 296 DGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPII 342 Score = 32.3 bits (72), Expect = 0.38, Method: Compositional matrix adjust. Identities = 20/79 (25%), Positives = 35/79 (44%), Gaps = 2/79 (2%) Query: 146 AVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALG 205 A+QT F + V FN + + +GG D ++VW + + + H + L+L Sbjct: 186 AIQT-FQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLS 244 Query: 206 PDGK-LVTVGRDLKASVWQ 223 +G L++ D VW Sbjct: 245 SEGSYLLSNAMDNTVRVWD 263 Score = 29.6 bits (65), Expect = 2.8, Method: Compositional matrix adjust. Identities = 17/56 (30%), Positives = 25/56 (44%), Gaps = 1/56 (1%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDG-KLVTVGRD 216 +N D ++L + TD V VW + E+V K H + G +LV G D Sbjct: 117 YNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSD 172 >5FL8-q nrPDB Length = 515 Score = 33.5 bits (75), Expect = 0.16, Method: Compositional matrix adjust. Identities = 25/111 (22%), Positives = 43/111 (38%), Gaps = 6/111 (5%) Query: 285 WDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGI 344 WD P+ T + V C+ S G + G++ ++ ++ S QCL H Sbjct: 171 WDCDTQTPMHTLKGHYNWVLCVSWSPDGEVIATGSMDNTIRLWDPKSGQCLGDALRGHSK 230 Query: 345 VVTDVAFLP----EKGRGPELLGSHETALFSV--AVDSRCQLHLLPSRRSV 389 +T +++ P + G P L S + + V CQ + SV Sbjct: 231 WITSLSWEPIHLVKPGSKPRLASSSKDGTIKIWDTVSRVCQYTMSGHTNSV 281 Score = 31.2 bits (69), Expect = 0.97, Method: Compositional matrix adjust. Identities = 12/51 (23%), Positives = 24/51 (47%) Query: 164 HDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVG 214 H ++ + TG D R+W + + K H + ++ PDG+++ G Sbjct: 154 HTSSRMVTGAGDNTARIWDCDTQTPMHTLKGHYNWVLCVSWSPDGEVIATG 204 Score = 30.8 bits (68), Expect = 1.2, Method: Compositional matrix adjust. Identities = 17/64 (26%), Positives = 32/64 (50%), Gaps = 1/64 (1%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDLK 218 V ++ D LL + D ++VW V + + ++ H+ E+ + DGK V + G+D Sbjct: 450 VAWSSDCRLLVSCSKDTTLKVWDVRTRKLSVDLPGHKDEVYTVDWSVDGKRVCSGGKDKM 509 Query: 219 ASVW 222 +W Sbjct: 510 VRLW 513 >5NZU-C nrPDB Length = 905 Score = 33.5 bits (75), Expect = 0.17, Method: Compositional matrix adjust. Identities = 18/59 (30%), Positives = 30/59 (50%), Gaps = 1/59 (1%) Query: 169 LATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDLKASVWQKDQ 226 + TG D +RV+ +LE+V F+AH I +A+ P + T D+ +W D+ Sbjct: 72 VVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDK 130 >5I2T-A nrPDB Length = 742 Score = 33.5 bits (75), Expect = 0.18, Method: Compositional matrix adjust. Identities = 21/76 (27%), Positives = 35/76 (46%), Gaps = 11/76 (14%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEF------KAHEGEIED---LALGPDGKL 210 V F+ D L A + ++++WK P + K +F + H G +D L D + Sbjct: 127 VKFSPDGRLFALA-SGRFLQIWKTPDVNKDRQFAPFVRHRVHAGHFQDITSLTWSQDSRF 185 Query: 211 V-TVGRDLKASVWQKD 225 + T +DL A +W D Sbjct: 186 ILTTSKDLSAKIWSVD 201 Score = 32.7 bits (73), Expect = 0.31, Method: Compositional matrix adjust. Identities = 15/54 (27%), Positives = 30/54 (55%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTV 213 + F+ +N++LA+ D +R+W + + +E ++ L++ PDGK V V Sbjct: 504 LSFSQENSVLASASWDKTIRIWSIFGRSQQVEPIEVYSDVLALSMRPDGKEVAV 557 >5Y1U-A nrPDB Length = 456 Score = 33.5 bits (75), Expect = 0.18, Method: Compositional matrix adjust. Identities = 19/59 (32%), Positives = 33/59 (55%), Gaps = 3/59 (5%) Query: 168 LLATGGTDGYVRVWKVPSLE-KVLEFKAHEGEIEDLALGPDGK--LVTVGRDLKASVWQ 223 +LATG D V +W + +L+ K+ F++H+ EI + P + L + G D + +VW Sbjct: 319 ILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWD 377 Score = 30.0 bits (66), Expect = 1.7, Method: Compositional matrix adjust. Identities = 25/102 (24%), Positives = 41/102 (40%), Gaps = 16/102 (15%) Query: 138 ELRVENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSL----------- 186 +LR L+ + D + +V H+ T+LA+ GTD + VW + + Sbjct: 333 DLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAED 392 Query: 187 ---EKVLEFKAHEGEIEDLALGPDGKLV--TVGRDLKASVWQ 223 E + H +I D + P+ V +V D VWQ Sbjct: 393 GPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQ 434 >5WLC-LO nrPDB Length = 923 Score = 33.5 bits (75), Expect = 0.20, Method: Compositional matrix adjust. Identities = 21/76 (27%), Positives = 35/76 (46%), Gaps = 11/76 (14%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEF------KAHEGEIED---LALGPDGKL 210 V F+ D L A + ++++WK P + K +F + H G +D L D + Sbjct: 102 VKFSPDGRLFALA-SGRFLQIWKTPDVNKDRQFAPFVRHRVHAGHFQDITSLTWSQDSRF 160 Query: 211 V-TVGRDLKASVWQKD 225 + T +DL A +W D Sbjct: 161 ILTTSKDLSAKIWSVD 176 Score = 32.7 bits (73), Expect = 0.32, Method: Compositional matrix adjust. Identities = 15/55 (27%), Positives = 30/55 (54%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVG 214 + F+ +N++LA+ D +R+W + + +E ++ L++ PDGK V V Sbjct: 479 LSFSQENSVLASASWDKTIRIWSIFGRSQQVEPIEVYSDVLALSMRPDGKEVAVS 533 >4G56-B nrPDB Length = 357 Score = 33.1 bits (74), Expect = 0.20, Method: Compositional matrix adjust. Identities = 19/75 (25%), Positives = 33/75 (44%), Gaps = 2/75 (2%) Query: 151 FSSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLAL--GPDG 208 + D + K + D T +GG D V+VW + + + AH E+ +A G D Sbjct: 136 YEHDDIVKTLSVFSDGTQAVSGGKDFSVKVWDLSQKAVLKSYNAHSSEVNCVAACPGKDT 195 Query: 209 KLVTVGRDLKASVWQ 223 ++ G D + +W Sbjct: 196 IFLSCGEDGRILLWD 210 >3JRO-A nrPDB Length = 753 Score = 33.1 bits (74), Expect = 0.21, Method: Compositional matrix adjust. Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 12/68 (17%) Query: 169 LATGGTDGYVRVWKVPS------LEKVLEFKAHEGEIEDLALGPD----GKLVTVGRDLK 218 TGG D V++WK S LE LE H + D+A P L +V +D Sbjct: 173 FVTGGADNLVKIWKYNSDAQTYVLESTLE--GHSDWVRDVAWSPTVLLRSYLASVSQDRT 230 Query: 219 ASVWQKDQ 226 +W +D Sbjct: 231 CIIWTQDN 238 >3CFV-B nrPDB Length = 414 Score = 33.1 bits (74), Expect = 0.22, Method: Compositional matrix adjust. Identities = 19/59 (32%), Positives = 33/59 (55%), Gaps = 3/59 (5%) Query: 168 LLATGGTDGYVRVWKVPSLE-KVLEFKAHEGEIEDLALGPDGK--LVTVGRDLKASVWQ 223 +LATG D V +W + +L+ K+ F++H+ EI + P + L + G D + +VW Sbjct: 290 ILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWD 348 Score = 29.6 bits (65), Expect = 2.6, Method: Compositional matrix adjust. Identities = 24/102 (23%), Positives = 41/102 (40%), Gaps = 16/102 (15%) Query: 138 ELRVENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSL----------- 186 +LR L+ + D + +V H+ T+LA+ GTD + VW + + Sbjct: 304 DLRNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAED 363 Query: 187 ---EKVLEFKAHEGEIEDLALGPDGKLV--TVGRDLKASVWQ 223 E + H +I D + P+ V +V D +WQ Sbjct: 364 GPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQIWQ 405 >2HES-X nrPDB Length = 330 Score = 33.1 bits (74), Expect = 0.24, Method: Compositional matrix adjust. Identities = 23/75 (30%), Positives = 38/75 (50%), Gaps = 5/75 (6%) Query: 157 QKVVCFNHDNTLLATGGTDGYVRVWKVP----SLEKVLEFKAHEGEIEDLALGPDGKLVT 212 +K+ F+ +LATG TD +++ V +L VL+ AH+ I +A P L+ Sbjct: 15 EKIWSFDFSQGILATGSTDRKIKLVSVKYDDFTLIDVLDETAHKKAIRSVAWRPHTSLLA 74 Query: 213 VGR-DLKASVWQKDQ 226 G D S+W K++ Sbjct: 75 AGSFDSTVSIWAKEE 89 >3C9C-A nrPDB Length = 432 Score = 33.1 bits (74), Expect = 0.25, Method: Compositional matrix adjust. Identities = 19/59 (32%), Positives = 32/59 (54%), Gaps = 3/59 (5%) Query: 168 LLATGGTDGYVRVWKVPSLE-KVLEFKAHEGEIEDLALGPDGK--LVTVGRDLKASVWQ 223 +LATG D V +W + +L+ K+ F++H+ EI + P + L + G D + VW Sbjct: 294 ILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWD 352 Score = 29.6 bits (65), Expect = 2.4, Method: Compositional matrix adjust. Identities = 24/102 (23%), Positives = 41/102 (40%), Gaps = 16/102 (15%) Query: 138 ELRVENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSL----------- 186 +LR L+ + D + +V H+ T+LA+ GTD + VW + + Sbjct: 308 DLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEEQSTEDAED 367 Query: 187 ---EKVLEFKAHEGEIEDLALGPDGKLV--TVGRDLKASVWQ 223 E + H +I D + P+ + +V D VWQ Sbjct: 368 GPPELLFIHGGHTAKISDFSWNPNEPWIICSVSEDNIMQVWQ 409 >2YNP-A nrPDB Length = 604 Score = 32.7 bits (73), Expect = 0.28, Method: Compositional matrix adjust. Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 8/68 (11%) Query: 169 LATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQKDQLV 228 + G D +RV+ + EKV++F+AH I +A+ P V G D D V Sbjct: 70 IIVGSDDFRIRVFNYNTGEKVVDFEAHPDYIRSIAVHPTKPYVLSGSD--------DLTV 121 Query: 229 TQLHWQEN 236 +W+ N Sbjct: 122 KLWNWENN 129 >5K1B-B nrPDB Length = 677 Score = 32.7 bits (73), Expect = 0.29, Method: Compositional matrix adjust. Identities = 14/49 (28%), Positives = 26/49 (53%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDG 208 + N T++ +G T+ +RVW + K+++ K H ++ L L DG Sbjct: 174 LAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDG 222 Score = 30.4 bits (67), Expect = 1.4, Method: Compositional matrix adjust. Identities = 16/59 (27%), Positives = 27/59 (45%), Gaps = 4/59 (6%) Query: 169 LATGGTDGYVRVWKVPSLEK---VLEFKAHEGEIEDLALGPDGK-LVTVGRDLKASVWQ 223 L T G D +R+W V ++ + + H + D+ L +GK L++ D VW Sbjct: 45 LFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDIVLCCNGKTLISASSDTTVKVWN 103 >3MKQ-A nrPDB Length = 814 Score = 32.7 bits (73), Expect = 0.32, Method: Compositional matrix adjust. Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 8/68 (11%) Query: 169 LATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQKDQLV 228 + G D +RV+ + EKV++F+AH I +A+ P V G D D V Sbjct: 70 IIVGSDDFRIRVFNYNTGEKVVDFEAHPDYIRSIAVHPTKPYVLSGSD--------DLTV 121 Query: 229 TQLHWQEN 236 +W+ N Sbjct: 122 KLWNWENN 129 >5MC6-j nrPDB Length = 397 Score = 32.3 bits (72), Expect = 0.38, Method: Compositional matrix adjust. Identities = 16/56 (28%), Positives = 25/56 (44%) Query: 145 QAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIE 200 QA +F+ + FN L + G DG +R W V + E++ H +IE Sbjct: 282 QASLGEFAHSSWVMSLSFNDSGETLCSAGWDGKLRFWDVKTKERITTLNMHCDDIE 337 >5OQL-d nrPDB Length = 446 Score = 32.3 bits (72), Expect = 0.40, Method: Compositional matrix adjust. Identities = 24/90 (26%), Positives = 38/90 (42%), Gaps = 7/90 (7%) Query: 169 LATGGTDGYVRVWKVPSL-EKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQ---- 223 +A+G DG V+VW + + E+ AH ++ L D KL++ D +W Sbjct: 82 IASGSGDGVVKVWDLTTRDEETWRVAAHNNIVKGLTFTNDKKLLSCATD-GIKLWDPYAS 140 Query: 224 KDQLVTQLHWQENGPTFSSTPYRYQACRFG 253 WQE GP ++S + A F Sbjct: 141 PSNTTPIATWQEGGP-YTSLSFHRSANTFA 169 >5N4A-A nrPDB Length = 771 Score = 32.3 bits (72), Expect = 0.40, Method: Compositional matrix adjust. Identities = 28/106 (26%), Positives = 44/106 (41%), Gaps = 4/106 (3%) Query: 138 ELRVENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRVW-KVPSLEKVLEFKAHE 196 E +V L A TD P+ + A TDG V++ + +EK +E H+ Sbjct: 47 EQKVSTLDAYFTDMHWYPVSSKKTQAGGTDVFAVACTDGSVKILSRTGRVEKSIE--GHK 104 Query: 197 GEIEDLALGPDGK-LVTVGRDLKASVWQKDQLVTQLHWQENGPTFS 241 G L DG L T G D +W ++ ++ Q + P +S Sbjct: 105 GACISLRWSYDGTALATAGEDGSVKIWSRNGMLRSTLAQADSPVYS 150 >3JRP-A nrPDB Length = 379 Score = 32.0 bits (71), Expect = 0.47, Method: Compositional matrix adjust. Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 12/68 (17%) Query: 169 LATGGTDGYVRVWKVPS------LEKVLEFKAHEGEIEDLALGPD----GKLVTVGRDLK 218 TGG D V++WK S LE LE H + D+A P L +V +D Sbjct: 175 FVTGGADNLVKIWKYNSDAQTYVLESTLE--GHSDWVRDVAWSPTVLLRSYLASVSQDRT 232 Query: 219 ASVWQKDQ 226 +W +D Sbjct: 233 CIIWTQDN 240 >5A9Q-0 nrPDB Length = 380 Score = 32.0 bits (71), Expect = 0.49, Method: Compositional matrix adjust. Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 5/74 (6%) Query: 155 PLQKVVCFNHDNTLLATGGTDGYVRVWKV-PSLEKVLEFKAHEGEIEDLALGPDG--KLV 211 PL V + ++ATGG DG + +W V V KAHE E+ ++ P L Sbjct: 219 PLHCVDRHPNQQHVVATGGQDGMLSIWDVRQGTMPVSLLKAHEAEMWEVHFHPSNPEHLF 278 Query: 212 TVGRDLKASVWQKD 225 T D S+W D Sbjct: 279 TCSED--GSLWHWD 290 >4BZK-B nrPDB Length = 297 Score = 31.6 bits (70), Expect = 0.60, Method: Compositional matrix adjust. Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 12/68 (17%) Query: 169 LATGGTDGYVRVWKVPS------LEKVLEFKAHEGEIEDLALGPD----GKLVTVGRDLK 218 TGG D V++WK S LE LE H + D+A P L +V +D Sbjct: 173 FVTGGADNLVKIWKYNSDAQTYVLESTLE--GHSDWVRDVAWSPTVLLRSYLASVSQDRT 230 Query: 219 ASVWQKDQ 226 +W +D Sbjct: 231 CIIWTQDN 238 >3J7Y-U nrPDB Length = 153 Score = 31.6 bits (70), Expect = 0.62, Method: Compositional matrix adjust. Identities = 23/60 (38%), Positives = 27/60 (45%), Gaps = 3/60 (5%) Query: 337 YVREAHGIVVTDVAFLPEKGRGPELLGSHETALFSVAVDSRCQLHLL-PSRRSVPVWLLL 395 YV+ AHG T PEK PE GS L+S+ + R Q P R VP W L Sbjct: 96 YVQLAHGQTFTFPDLFPEKDESPE--GSAADDLYSMLEEERQQRQSSDPRRGGVPSWFGL 153 >5UZ7-B nrPDB Length = 351 Score = 31.6 bits (70), Expect = 0.67, Method: Compositional matrix adjust. Identities = 18/63 (28%), Positives = 31/63 (49%), Gaps = 2/63 (3%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGR-DLKAS 220 F DN ++ + G D +W + + ++ F H G++ L+L PD +L G D A Sbjct: 162 FLDDNQIVTSSG-DTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAK 220 Query: 221 VWQ 223 +W Sbjct: 221 LWD 223 Score = 30.8 bits (68), Expect = 1.0, Method: Compositional matrix adjust. Identities = 14/52 (26%), Positives = 20/52 (38%) Query: 165 DNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRD 216 D L +G D ++W V F HE +I + P+G G D Sbjct: 206 DTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSD 257 >5A31-R nrPDB Length = 386 Score = 31.6 bits (70), Expect = 0.69, Method: Compositional matrix adjust. Identities = 20/66 (30%), Positives = 32/66 (48%), Gaps = 4/66 (6%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPD--GKLVTVG--RDL 217 +N + LA+GG D V V++ S +L F H+ ++ +A P G L T G D Sbjct: 222 WNVADNKLASGGNDNVVHVYEGTSKSPILTFDEHKAAVKAMAWSPHKRGVLATGGGTADR 281 Query: 218 KASVWQ 223 + +W Sbjct: 282 RLKIWN 287 >2E1U-A nrPDB Length = 454 Score = 31.6 bits (70), Expect = 0.69, Method: Compositional matrix adjust. Identities = 34/123 (27%), Positives = 53/123 (43%), Gaps = 10/123 (8%) Query: 163 NHDNTLLATGGTDGYVRVWKVPSLEKVLEFKA-----HEGEIEDLALGPDGKLVTVGRDL 217 N+D + LA G Y R+ K P L++ +A +E + GP KL Sbjct: 193 NNDESFLANGTRPLYDRIIKYPMLDEAYLKRAKVESFNEDYVTQSLAGPSDKLRATFILT 252 Query: 218 KASVWQ-KDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQ 276 +A + Q KD+++ QL E +F+ +C D+ L+LF I +R R Sbjct: 253 RAVINQLKDRVLAQLPTLEYVSSFTVACAYIWSCIAKSRNDK---LQLFGFPI-DRRARM 308 Query: 277 PPP 279 PP Sbjct: 309 KPP 311 >5OQL-X nrPDB Length = 630 Score = 31.2 bits (69), Expect = 0.76, Method: Compositional matrix adjust. Identities = 19/71 (26%), Positives = 30/71 (42%), Gaps = 1/71 (1%) Query: 159 VVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGP-DGKLVTVGRDL 217 VV + D + TGG D + V+ L+ + F H + LA +L + +D Sbjct: 251 VVKASQDGKFVVTGGADKRLVVYNAADLKPIKAFTQHRDAVTGLAFRRGTNQLYSCSKDR 310 Query: 218 KASVWQKDQLV 228 VW D+L Sbjct: 311 TVKVWSLDELA 321 Score = 29.3 bits (64), Expect = 3.3, Method: Compositional matrix adjust. Identities = 22/66 (33%), Positives = 32/66 (48%), Gaps = 3/66 (4%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDL-ALGPDGKLVTVG-RDL 217 + F L + D V+VW + L V H+ EI D+ ALG + + V+VG RD Sbjct: 294 LAFRRGTNQLYSCSKDRTVKVWSLDELAYVETLFGHQDEILDIDALGQE-RCVSVGARDR 352 Query: 218 KASVWQ 223 A W+ Sbjct: 353 TARYWK 358 >6N9G-C nrPDB Length = 353 Score = 31.2 bits (69), Expect = 0.78, Method: Compositional matrix adjust. Identities = 16/51 (31%), Positives = 24/51 (47%), Gaps = 1/51 (1%) Query: 166 NTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRD 216 NT + +GG D VW + S + V F+ HE ++ + P G G D Sbjct: 210 NTFV-SGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGDAFASGSD 259 Score = 30.8 bits (68), Expect = 1.2, Method: Compositional matrix adjust. Identities = 19/65 (29%), Positives = 28/65 (43%), Gaps = 3/65 (4%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPD---GKLVTVGRDLK 218 F + + + T DG +W V S + + F H ++ L L P V+ G D K Sbjct: 161 FTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKK 220 Query: 219 ASVWQ 223 A VW Sbjct: 221 AMVWD 225 Score = 28.9 bits (63), Expect = 4.2, Method: Compositional matrix adjust. Identities = 20/64 (31%), Positives = 25/64 (39%), Gaps = 1/64 (1%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGR-DLK 218 V F+ LL G D + VW V +V HE + L + PDG G D Sbjct: 289 VDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHT 348 Query: 219 ASVW 222 VW Sbjct: 349 LRVW 352 >5WLC-LN nrPDB Length = 776 Score = 31.2 bits (69), Expect = 0.84, Method: Compositional matrix adjust. Identities = 14/45 (31%), Positives = 24/45 (53%) Query: 282 LTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAI 326 +T WD + LPLR C V+ + +++S L +G G+V + Sbjct: 123 VTEWDLATGLPLRNYDCNSGVIWSISINDSQDKLSVGCDNGTVVL 167 >4BH6-A nrPDB Length = 308 Score = 31.2 bits (69), Expect = 0.91, Method: Compositional matrix adjust. Identities = 20/66 (30%), Positives = 32/66 (48%), Gaps = 4/66 (6%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPD--GKLVTVG--RDL 217 +N + LA+GG D V V++ S +L F H+ ++ +A P G L T G D Sbjct: 153 WNVADNKLASGGNDNVVHVYEGTSKSPILTFDEHKAAVKAMAWSPHKRGVLATGGGTADR 212 Query: 218 KASVWQ 223 + +W Sbjct: 213 RLKIWN 218 >5OQL-J nrPDB Length = 912 Score = 31.2 bits (69), Expect = 0.97, Method: Compositional matrix adjust. Identities = 20/77 (25%), Positives = 34/77 (44%), Gaps = 8/77 (10%) Query: 162 FNHDNTLLATGGTDGYVRVWKVP-------SLEKVLEFKAHEGEIEDLALGPDGKL-VTV 213 +H L +G D +V+ +P L L AH+ +I L + P+GKL + Sbjct: 503 LDHPPAFLISGSQDRFVQKRDIPRQLQKGGKLTSSLRRLAHDKDINALDISPNGKLFASA 562 Query: 214 GRDLKASVWQKDQLVTQ 230 +D +W ++L Q Sbjct: 563 SQDKTVKIWDVEKLEVQ 579 Score = 29.6 bits (65), Expect = 2.5, Method: Compositional matrix adjust. Identities = 10/25 (40%), Positives = 17/25 (68%) Query: 159 VVCFNHDNTLLATGGTDGYVRVWKV 183 V+ + +TLLATG DG +++W + Sbjct: 116 VLAVDRTSTLLATGAADGAIKIWDI 140 Score = 28.5 bits (62), Expect = 5.2, Method: Compositional matrix adjust. Identities = 16/56 (28%), Positives = 24/56 (42%), Gaps = 1/56 (1%) Query: 169 LATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLAL-GPDGKLVTVGRDLKASVWQ 223 A+ G D V+VW + E HE + LA+ L + G D K + W+ Sbjct: 666 FASAGADTLVKVWDANTGETECTLDNHEDRLWTLAVHSKTNILASAGSDSKVTFWR 721 >6IYY-A nrPDB Length = 317 Score = 30.8 bits (68), Expect = 1.0, Method: Compositional matrix adjust. Identities = 21/60 (35%), Positives = 34/60 (56%), Gaps = 2/60 (3%) Query: 159 VVCFNHDNTLLATGGT-DGYVRVWKVPSLEK-VLEFKAHEGEIEDLALGPDGKLVTVGRD 216 V+C N +N+LLA GT G+V++ + S EK ++ AHEG + +AL G + + Sbjct: 137 VLCPNSNNSLLAFPGTHTGHVQLVDLASTEKPPVDIPAHEGVLSCIALNLQGTRIATASE 196 >4J0X-A nrPDB Length = 451 Score = 30.8 bits (68), Expect = 1.2, Method: Compositional matrix adjust. Identities = 17/36 (47%), Positives = 21/36 (58%), Gaps = 1/36 (2%) Query: 193 KAHEGEIEDLALGPDGK-LVTVGRDLKASVWQKDQL 227 + H EI +A PDGK +VT GRD K VW + L Sbjct: 111 EGHYDEILTVAASPDGKYVVTGGRDRKLIVWSTESL 146 >2AQ5-A nrPDB Length = 402 Score = 30.4 bits (67), Expect = 1.3, Method: Compositional matrix adjust. Identities = 19/78 (24%), Positives = 35/78 (44%), Gaps = 9/78 (11%) Query: 155 PLQKVVCFNHDNTLLATGGTDGYVRVWKVPS-------LEKVLEFKAHEGEIEDLALGPD 207 P+ + H++ ++A+G D V VW++P E V+ + H + +A P Sbjct: 83 PVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLVLPLREPVITLEGHTKRVGIVAWHPT 142 Query: 208 GK--LVTVGRDLKASVWQ 223 + L++ G D VW Sbjct: 143 AQNVLLSAGCDNVILVWD 160 >5YZG-W nrPDB Length = 579 Score = 30.4 bits (67), Expect = 1.4, Method: Compositional matrix adjust. Identities = 20/79 (25%), Positives = 34/79 (43%), Gaps = 4/79 (5%) Query: 151 FSSDPLQKVVCFNHDN---TLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLA-LGP 206 F++ + V FN D L G +D + W + S E V E+ H G + + + Sbjct: 370 FTNRKVPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDE 429 Query: 207 DGKLVTVGRDLKASVWQKD 225 + + V+ D VW+ D Sbjct: 430 NRRFVSTSDDKSLRVWEWD 448 >3ODT-A nrPDB Length = 313 Score = 30.4 bits (67), Expect = 1.5, Method: Compositional matrix adjust. Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 11/84 (13%) Query: 154 DPL------QKVVC-FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLAL-- 204 DPL Q VC + + ++ +G D +VWK SL V +AH + D + Sbjct: 95 DPLYTLIGHQGNVCSLSFQDGVVISGSWDKTAKVWKEGSL--VYNLQAHNASVWDAKVVS 152 Query: 205 GPDGKLVTVGRDLKASVWQKDQLV 228 + K +T D +WQ D+++ Sbjct: 153 FSENKFLTASADKTIKLWQNDKVI 176 Score = 30.4 bits (67), Expect = 1.5, Method: Compositional matrix adjust. Identities = 22/95 (23%), Positives = 40/95 (42%), Gaps = 10/95 (10%) Query: 160 VCFNHDNTLLATGGTDGYVR---VWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRD 216 VC++ + LL GG D + ++ + + H+G + L+ DG +++ D Sbjct: 65 VCYDSEKELLLFGGKDTMINGVPLFATSGEDPLYTLIGHQGNVCSLSF-QDGVVISGSWD 123 Query: 217 LKASVWQKDQLVTQLH------WQENGPTFSSTPY 245 A VW++ LV L W +FS + Sbjct: 124 KTAKVWKEGSLVYNLQAHNASVWDAKVVSFSENKF 158 Score = 29.6 bits (65), Expect = 2.4, Method: Compositional matrix adjust. Identities = 13/62 (20%), Positives = 31/62 (50%) Query: 165 DNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQK 224 D+ + DG +++ + + + + ++ HE + + L P+G +V+ G D +W K Sbjct: 194 DDGHFISCSNDGLIKLVDMHTGDVLRTYEGHESFVYCIKLLPNGDIVSCGEDRTVRIWSK 253 Query: 225 DQ 226 + Sbjct: 254 EN 255 >3M1Y-A nrPDB Length = 217 Score = 30.4 bits (67), Expect = 1.5, Method: Compositional matrix adjust. Identities = 15/46 (32%), Positives = 22/46 (47%) Query: 155 PLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIE 200 LQK+ F+ D+TL+ + R W V K + KA GE + Sbjct: 2 SLQKLAVFDFDSTLVNAETIESLARAWGVFDEVKTITLKAMNGETD 47 >5CXB-B nrPDB Length = 369 Score = 30.4 bits (67), Expect = 1.6, Method: Compositional matrix adjust. Identities = 19/71 (26%), Positives = 32/71 (45%), Gaps = 15/71 (21%) Query: 184 PSLEKVLEFKAHEGEIEDLALGPDG-KLVTVGRDLKASVWQ-------------KDQLVT 229 P++++ + F+ HEG + +A+ P G L T G D VW+ D+ V Sbjct: 10 PTVQQTI-FRGHEGRVRSVAIDPTGVALATGGDDGTVRVWELLTGRQVWSVKLNGDEAVN 68 Query: 230 QLHWQENGPTF 240 + W+ TF Sbjct: 69 TVRWRPTKDTF 79 Score = 29.6 bits (65), Expect = 2.8, Method: Compositional matrix adjust. Identities = 15/41 (36%), Positives = 22/41 (53%) Query: 158 KVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGE 198 + V + LATGG DG VRVW++ + +V K + E Sbjct: 25 RSVAIDPTGVALATGGDDGTVRVWELLTGRQVWSVKLNGDE 65 >6QDV-o nrPDB Length = 513 Score = 30.4 bits (67), Expect = 1.6, Method: Compositional matrix adjust. Identities = 20/79 (25%), Positives = 34/79 (43%), Gaps = 4/79 (5%) Query: 151 FSSDPLQKVVCFNHDN---TLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLA-LGP 206 F++ + V FN D L G +D + W + S E V E+ H G + + + Sbjct: 304 FTNRKVPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDE 363 Query: 207 DGKLVTVGRDLKASVWQKD 225 + + V+ D VW+ D Sbjct: 364 NRRFVSTSDDKSLRVWEWD 382 >6GMH-W nrPDB Length = 305 Score = 30.4 bits (67), Expect = 1.6, Method: Compositional matrix adjust. Identities = 13/57 (22%), Positives = 27/57 (47%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRD 216 + ++ D LA+G DG + ++ + + + + + H I L PD +L+ D Sbjct: 154 IAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASD 210 Score = 28.9 bits (63), Expect = 4.3, Method: Compositional matrix adjust. Identities = 13/50 (26%), Positives = 24/50 (48%) Query: 158 KVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPD 207 + + F+ D+ LL T DGY++++ V H + ++A PD Sbjct: 194 RSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPD 243 >5Y88-O nrPDB Length = 451 Score = 30.4 bits (67), Expect = 1.6, Method: Compositional matrix adjust. Identities = 15/57 (26%), Positives = 28/57 (49%), Gaps = 1/57 (1%) Query: 168 LLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGP-DGKLVTVGRDLKASVWQ 223 L+AT G D +++W + + V+ H+G I + P D ++V+ D +W Sbjct: 238 LIATAGRDSVIKLWDMRTRIPVITLVGHKGPINQVQCTPVDPQVVSSSTDATVRLWD 294 >5M25-A nrPDB Length = 434 Score = 30.4 bits (67), Expect = 1.7, Method: Compositional matrix adjust. Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 2/55 (3%) Query: 159 VVC--FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV 211 V C FN + L+ +G D VR+W V + + + AH + + DG L+ Sbjct: 232 VFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLI 286 Score = 29.6 bits (65), Expect = 2.8, Method: Compositional matrix adjust. Identities = 20/99 (20%), Positives = 37/99 (37%), Gaps = 13/99 (13%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGR-DLK 218 V ++ D+ LL + D +++W V S + + K H + P L+ G D Sbjct: 193 VAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDES 252 Query: 219 ASVWQ------------KDQLVTQLHWQENGPTFSSTPY 245 +W V+ +H+ +G S+ Y Sbjct: 253 VRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSY 291 Score = 29.3 bits (64), Expect = 3.2, Method: Compositional matrix adjust. Identities = 13/33 (39%), Positives = 18/33 (54%), Gaps = 1/33 (3%) Query: 153 SDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPS 185 SDP+ V FN D +L+ + DG R+W S Sbjct: 271 SDPVS-AVHFNRDGSLIVSSSYDGLCRIWDTAS 302 >5WLC-SG nrPDB Length = 573 Score = 30.0 bits (66), Expect = 1.8, Method: Compositional matrix adjust. Identities = 17/36 (47%), Positives = 21/36 (58%), Gaps = 1/36 (2%) Query: 193 KAHEGEIEDLALGPDGK-LVTVGRDLKASVWQKDQL 227 + H EI +A PDGK +VT GRD K VW + L Sbjct: 233 EGHYDEILTVAASPDGKYVVTGGRDRKLIVWSTESL 268 >2H9P-A nrPDB Length = 329 Score = 30.0 bits (66), Expect = 1.8, Method: Compositional matrix adjust. Identities = 14/50 (28%), Positives = 24/50 (48%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV 211 FN + L+ +G D VR+W V + + + AH + + DG L+ Sbjct: 132 FNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLI 181 Score = 29.3 bits (64), Expect = 3.0, Method: Compositional matrix adjust. Identities = 15/65 (23%), Positives = 27/65 (41%), Gaps = 1/65 (1%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGR-DLK 218 V ++ D+ LL + D +++W V S + + K H + P L+ G D Sbjct: 88 VAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDES 147 Query: 219 ASVWQ 223 +W Sbjct: 148 VRIWD 152 Score = 28.9 bits (63), Expect = 4.6, Method: Compositional matrix adjust. Identities = 13/33 (39%), Positives = 18/33 (54%), Gaps = 1/33 (3%) Query: 153 SDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPS 185 SDP+ V FN D +L+ + DG R+W S Sbjct: 166 SDPVS-AVHFNRDGSLIVSSSYDGLCRIWDTAS 197 >1NR0-A nrPDB Length = 611 Score = 30.0 bits (66), Expect = 1.8, Method: Compositional matrix adjust. Identities = 23/87 (26%), Positives = 37/87 (42%), Gaps = 5/87 (5%) Query: 142 ENLQAVQTDFSSDPLQKVVC--FNHDNTLLATGGTDGYVRVWKV--PSLEKVLEFKAHE- 196 N + T+ + KV C ++ DN LATG D V VW + PS ++ AH Sbjct: 522 NNFELAHTNSWTFHTAKVACVSWSPDNVRLATGSLDNSVIVWNMNKPSDHPIIIKGAHAM 581 Query: 197 GEIEDLALGPDGKLVTVGRDLKASVWQ 223 + + + +V+ G+D W Sbjct: 582 SSVNSVIWLNETTIVSAGQDSNIKFWN 608 >6ELZ-p nrPDB Length = 460 Score = 30.0 bits (66), Expect = 1.9, Method: Compositional matrix adjust. Identities = 15/56 (26%), Positives = 29/56 (51%), Gaps = 3/56 (5%) Query: 169 LATGGTDGYVRVWKVP-SLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQ 223 + +G DG VR W + +++K ++ H G I + + +LV+ G D +W+ Sbjct: 118 IISGSYDGIVRTWDLSGNVQK--QYSGHSGPIRAVKYISNTRLVSAGNDRTLRLWK 171 >5OV3-A nrPDB Length = 381 Score = 29.6 bits (65), Expect = 2.3, Method: Compositional matrix adjust. Identities = 21/63 (33%), Positives = 26/63 (41%), Gaps = 1/63 (1%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDG-KLVTVGRDLKAS 220 FN TLLA G DG + +W + AH + L DG KLV+ D S Sbjct: 33 FNRWGTLLAVGCNDGRIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDNIVS 92 Query: 221 VWQ 223 W Sbjct: 93 QWD 95 >5BJS-A nrPDB Length = 605 Score = 29.6 bits (65), Expect = 2.6, Method: Compositional matrix adjust. Identities = 20/74 (27%), Positives = 29/74 (39%), Gaps = 9/74 (12%) Query: 151 FSSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKL 210 +S DP+ D LL G +G V+V+ V + H G I DLA P Sbjct: 140 WSKDPIT-------DQPLLCIAGNEGNVKVYNVTEGKLYRTLVGHGGGINDLATSPANPY 192 Query: 211 V--TVGRDLKASVW 222 + + D +W Sbjct: 193 IIASASDDTTIRIW 206 >4AEZ-A nrPDB Length = 401 Score = 29.3 bits (64), Expect = 3.4, Method: Compositional matrix adjust. Identities = 18/64 (28%), Positives = 31/64 (48%), Gaps = 4/64 (6%) Query: 164 HDNTLLATGG-TDGYVRVWKVPS--LEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDLKA 219 H +++T G D + +W S L K ++ AH+ + AL PDG+++ T D Sbjct: 314 HSKEIMSTHGFPDNNLSIWSYSSSGLTKQVDIPAHDTRVLYSALSPDGRILSTAASDENL 373 Query: 220 SVWQ 223 W+ Sbjct: 374 KFWR 377 >5WYJ-BC nrPDB Length = 817 Score = 28.9 bits (63), Expect = 4.0, Method: Compositional matrix adjust. Identities = 16/37 (43%), Positives = 20/37 (54%) Query: 166 NTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDL 202 +TLLA GGTDG + V + + FK H G I L Sbjct: 114 STLLAVGGTDGSIIVVDIENGYITHSFKGHGGTISSL 150 Score = 28.5 bits (62), Expect = 5.2, Method: Compositional matrix adjust. Identities = 18/63 (28%), Positives = 31/63 (49%), Gaps = 7/63 (11%) Query: 168 LLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIE--DLALGPDG-----KLVTVGRDLKAS 220 LLA+G T+G V+VW + + + + H + D+ PD L++ GRD + Sbjct: 162 LLASGDTNGMVKVWDLVKRKCLHTLQEHTSAVRGLDIIEVPDNDEPSLNLLSGGRDDIIN 221 Query: 221 VWQ 223 +W Sbjct: 222 LWD 224 >4XFV-A nrPDB Length = 792 Score = 28.9 bits (63), Expect = 4.1, Method: Compositional matrix adjust. Identities = 20/88 (22%), Positives = 39/88 (44%), Gaps = 10/88 (11%) Query: 158 KVVCFNHDNT----LLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKL--- 210 K + F H T LL +G D Y+R+W++ + +++ + + L K Sbjct: 210 KSLAFRHQETPGDYLLCSGSQDRYIRLWRI-RINDLIDDSEEDSKKLTLLSNKQYKFQID 268 Query: 211 --VTVGRDLKASVWQKDQLVTQLHWQEN 236 + VG + +A + D ++ L W E+ Sbjct: 269 DELRVGINFEALIMGHDDWISSLQWHES 296 >3JAP-g nrPDB Length = 326 Score = 28.9 bits (63), Expect = 4.2, Method: Compositional matrix adjust. Identities = 14/65 (21%), Positives = 28/65 (43%), Gaps = 1/65 (1%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPD-GKLVTVGRDLK 218 V + D + D +R+W + + F H G++ +A+ + K+++ RD Sbjct: 72 VVVSADGNYAVSASWDKTLRLWNLATGNSEARFVGHTGDVLSVAIDANSSKIISASRDKT 131 Query: 219 ASVWQ 223 VW Sbjct: 132 IRVWN 136 Score = 28.5 bits (62), Expect = 6.0, Method: Compositional matrix adjust. Identities = 14/42 (33%), Positives = 21/42 (50%), Gaps = 1/42 (2%) Query: 165 DNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGP 206 D +L A+ G DG + VW + + F A + E+ LA P Sbjct: 214 DGSLAASAGKDGQIYVWNLKHKSAFMNFDAKD-EVFALAFSP 254 >5A9Q-7 nrPDB Length = 360 Score = 28.9 bits (63), Expect = 4.5, Method: Compositional matrix adjust. Identities = 12/29 (41%), Positives = 18/29 (62%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEK 188 V +N T+LA+ G DG VR+WK ++ Sbjct: 284 VSWNITGTVLASSGDDGCVRLWKANYMDN 312 >3JB9-L nrPDB Length = 340 Score = 28.5 bits (62), Expect = 5.8, Method: Compositional matrix adjust. Identities = 13/42 (30%), Positives = 21/42 (50%) Query: 167 TLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDG 208 T + GG DG +++W + + K H+ I LA+ DG Sbjct: 190 TQVFIGGIDGAIKIWDLRNNHCSHVLKGHKDIITSLAISKDG 231 >3F3P-A nrPDB Length = 351 Score = 28.1 bits (61), Expect = 6.7, Method: Compositional matrix adjust. Identities = 11/24 (45%), Positives = 16/24 (66%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKV 183 V +N T+L++ G DG VR+WK Sbjct: 312 VSWNLTGTILSSAGDDGKVRLWKA 335 >3JZG-A nrPDB Length = 402 Score = 28.1 bits (61), Expect = 6.9, Method: Compositional matrix adjust. Identities = 19/70 (27%), Positives = 33/70 (47%), Gaps = 4/70 (5%) Query: 163 NHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK--LVTVGRDLKAS 220 N + LLA G+ G +R+ +++ + + H I +L P L++V +D Sbjct: 118 NTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALR 177 Query: 221 VW--QKDQLV 228 +W Q D LV Sbjct: 178 LWNIQTDTLV 187 >5MWJ-A nrPDB Length = 337 Score = 28.1 bits (61), Expect = 7.5, Method: Compositional matrix adjust. Identities = 19/73 (26%), Positives = 32/73 (43%), Gaps = 1/73 (1%) Query: 152 SSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDG-KL 210 SS P + + D+ + + +DG + VW + + V +F+ H + + DG KL Sbjct: 139 SSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKL 198 Query: 211 VTVGRDLKASVWQ 223 T G D W Sbjct: 199 WTGGLDNTVRSWD 211 >4XYI-A nrPDB Length = 430 Score = 28.1 bits (61), Expect = 8.0, Method: Compositional matrix adjust. Identities = 21/91 (23%), Positives = 36/91 (39%), Gaps = 16/91 (17%) Query: 154 DPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSL--EKVLEFK------------AHEGEI 199 D + V HD +L T TD V VW + + E+ +E H + Sbjct: 326 DEVYNVQWSPHDEPILVTSSTDRRVCVWDLSKIGEEQTVEDSEDGAPELMFMHGGHTNRV 385 Query: 200 EDLALGPDGK--LVTVGRDLKASVWQKDQLV 228 DL+ P+ K L ++ D +W +++ Sbjct: 386 SDLSWNPNNKWVLASLADDNILQIWSPSKVI 416 >5K0Y-T nrPDB Length = 329 Score = 27.7 bits (60), Expect = 8.4, Method: Compositional matrix adjust. Identities = 14/37 (37%), Positives = 19/37 (51%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHE 196 V F+ D ++GG DGYVR+ EF+A E Sbjct: 291 VAFHPDGKSYSSGGEDGYVRIHYFDPQYFEFEFEARE 327 >5M89-A nrPDB Length = 329 Score = 27.7 bits (60), Expect = 8.9, Method: Compositional matrix adjust. Identities = 24/93 (25%), Positives = 44/93 (47%), Gaps = 4/93 (4%) Query: 125 EKKCGAETQHEGLELRVENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVP 184 E +C A +G +L + ++ A + + + D + V T + G G+V+V+ Sbjct: 62 ENECAAVGGLDG-KLDIYSVVANKVERTLDIGEPVTATEWTGTKVVIGTAKGWVKVYDAG 120 Query: 185 SLEKVLEFKAHEGEIEDLALGPDGK-LVTVGRD 216 + F+ H G + LA+ P G+ L +VG D Sbjct: 121 --RESATFQTHAGPVTGLAVHPGGRILASVGVD 151 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5TF2-A nrPDB 687 0.0 5NNZ-B nrPDB 218 5e-57 5OPT-p nrPDB 160 1e-39 4V6W-Ag nrPDB 131 5e-31 5XYI-g nrPDB 93 2e-19 4BTS-AR nrPDB 92 6e-19 6HQA-B nrPDB 91 1e-18 6EOJ-D nrPDB 83 2e-16 6Q8F-A nrPDB 72 5e-13 Sequences not found previously or not previously below threshold: 4V8M-A7 nrPDB 149 3e-36 5MZH-A nrPDB 145 4e-35 6G51-g nrPDB 124 7e-29 3DM0-A nrPDB 113 2e-25 5M25-A nrPDB 93 2e-19 2H9P-A nrPDB 93 2e-19 1VYH-C nrPDB 91 9e-19 6HHQ-h nrPDB 91 1e-18 6MZM-G nrPDB 89 3e-18 6F3T-A nrPDB 89 3e-18 6QX9-4B nrPDB 86 2e-17 3JAP-g nrPDB 76 3e-14 6QX9-5O nrPDB 74 1e-13 5MWJ-A nrPDB 74 1e-13 5FL8-q nrPDB 73 2e-13 5K1B-B nrPDB 71 1e-12 6E29-D nrPDB 69 4e-12 5WLC-LO nrPDB 67 1e-11 5I2T-A nrPDB 67 1e-11 5Z56-q nrPDB 67 2e-11 4LG8-A nrPDB 67 2e-11 5NZU-C nrPDB 66 3e-11 4U1E-I nrPDB 66 3e-11 5UZ7-B nrPDB 64 8e-11 6EMK-B nrPDB 64 1e-10 6ID0-T nrPDB 64 1e-10 3JB9-L nrPDB 64 1e-10 5FVM-C nrPDB 62 4e-10 6N9G-C nrPDB 62 6e-10 6GMH-W nrPDB 61 8e-10 3MKQ-A nrPDB 61 9e-10 2YNP-A nrPDB 61 9e-10 5WYJ-BC nrPDB 61 1e-09 3FM0-A nrPDB 60 2e-09 5Y88-O nrPDB 59 5e-09 5GAN-H nrPDB 59 5e-09 5WYK-BB nrPDB 58 8e-09 3ODT-A nrPDB 57 2e-08 4V7E-Bg nrPDB 57 2e-08 6QDV-o nrPDB 56 3e-08 5YZG-W nrPDB 56 3e-08 5OQL-d nrPDB 56 3e-08 5WLC-LU nrPDB 56 3e-08 6BX3-A nrPDB 56 4e-08 5OQL-J nrPDB 56 4e-08 4G56-B nrPDB 55 7e-08 3JB9-g nrPDB 55 7e-08 6J6H-n nrPDB 54 9e-08 5OQL-L nrPDB 54 2e-07 4PSX-B nrPDB 54 2e-07 4J0W-A nrPDB 53 2e-07 5N4A-A nrPDB 53 3e-07 4OWR-A nrPDB 53 3e-07 5K19-A nrPDB 53 3e-07 5FA5-B nrPDB 52 3e-07 6ELZ-p nrPDB 51 8e-07 5OQL-X nrPDB 51 1e-06 5K0Y-T nrPDB 50 1e-06 5WJC-A nrPDB 50 2e-06 5OV3-A nrPDB 49 5e-06 3C9C-A nrPDB 49 5e-06 5BJS-A nrPDB 49 5e-06 5WBU-D nrPDB 49 5e-06 3BG0-A nrPDB 49 5e-06 3CFV-B nrPDB 49 5e-06 4XYI-A nrPDB 48 6e-06 5WYJ-BE nrPDB 48 7e-06 6CHG-A nrPDB 48 7e-06 5Y1U-A nrPDB 48 7e-06 1NR0-A nrPDB 48 8e-06 2AQ5-A nrPDB 47 1e-05 6BX3-B nrPDB 47 1e-05 5WLC-LJ nrPDB 47 1e-05 5CXC-A nrPDB 47 2e-05 2HES-X nrPDB 47 2e-05 5A9Q-0 nrPDB 46 3e-05 4BZK-B nrPDB 46 3e-05 3JRP-A nrPDB 46 3e-05 3JRO-A nrPDB 46 3e-05 4AEZ-A nrPDB 46 3e-05 3ACP-A nrPDB 45 4e-05 6CHG-D nrPDB 45 6e-05 4GGA-A nrPDB 45 7e-05 5LCW-Q nrPDB 45 7e-05 5G04-R nrPDB 45 7e-05 4N14-A nrPDB 45 7e-05 5YZG-2 nrPDB 44 9e-05 4L9O-A nrPDB 44 1e-04 5M89-A nrPDB 44 1e-04 5L9T-R nrPDB 44 1e-04 4XFV-A nrPDB 44 1e-04 4YCZ-A nrPDB 43 3e-04 3JZG-A nrPDB 42 4e-04 5WLC-SG nrPDB 42 6e-04 4J0X-A nrPDB 42 6e-04 4A11-B nrPDB 42 6e-04 3JB9-S nrPDB 41 9e-04 3W15-A nrPDB 41 0.001 5WLC-LN nrPDB 40 0.001 5CXB-B nrPDB 40 0.002 5A9Q-7 nrPDB 40 0.002 2P9P-C nrPDB 40 0.003 3I2N-A nrPDB 39 0.005 5WLC-LH nrPDB 39 0.006 5WLC-LW nrPDB 38 0.007 5A9Q-2 nrPDB 38 0.009 5A31-R nrPDB 38 0.010 4BH6-A nrPDB 38 0.010 5MC6-j nrPDB 37 0.011 6EM1-m nrPDB 37 0.022 6CB1-s nrPDB 37 0.022 6C0F-s nrPDB 37 0.022 1PI6-A nrPDB 36 0.033 4E5Z-B nrPDB 36 0.034 1EJI-A nrPDB 35 0.040 6F1U-h nrPDB 35 0.046 2I3T-A nrPDB 35 0.048 2PM9-A nrPDB 35 0.078 5LTD-A nrPDB 34 0.10 6IYY-A nrPDB 34 0.17 3DW8-B nrPDB 34 0.19 3F3P-A nrPDB 34 0.19 5AJA-A nrPDB 33 0.20 5WLC-LS nrPDB 31 0.89 5BPW-A nrPDB 31 1.2 2VDU-B nrPDB 30 1.4 4V0N-B nrPDB 30 2.6 2X86-A nrPDB 30 2.7 1EQ2-A nrPDB 30 2.7 1BJ4-A nrPDB 29 2.9 6N8P-A nrPDB 29 3.0 5DKU-A nrPDB 29 4.3 5SUM-A nrPDB 29 4.4 2FTW-A nrPDB 29 5.2 5AMS-A nrPDB 29 5.6 4MHC-A nrPDB 28 9.2 >5TF2-A nrPDB Length = 407 Score = 687 bits (1773), Expect = 0.0, Method: Composition-based stats. Identities = 389/389 (100%), Positives = 389/389 (100%) Query: 1 MGRRRAPELYRAPFPLYALQVDPSTGLLIAAGGGGAAKTGIKNGVHFLQLELINGRLSAS 60 MGRRRAPELYRAPFPLYALQVDPSTGLLIAAGGGGAAKTGIKNGVHFLQLELINGRLSAS Sbjct: 19 MGRRRAPELYRAPFPLYALQVDPSTGLLIAAGGGGAAKTGIKNGVHFLQLELINGRLSAS 78 Query: 61 LLHSHDTETRATMNLALAGDILAAGQDAHCQLLRFQAHQQQGNKAEKAGSKEQGPRQRKG 120 LLHSHDTETRATMNLALAGDILAAGQDAHCQLLRFQAHQQQGNKAEKAGSKEQGPRQRKG Sbjct: 79 LLHSHDTETRATMNLALAGDILAAGQDAHCQLLRFQAHQQQGNKAEKAGSKEQGPRQRKG 138 Query: 121 AAPAEKKCGAETQHEGLELRVENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRV 180 AAPAEKKCGAETQHEGLELRVENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRV Sbjct: 139 AAPAEKKCGAETQHEGLELRVENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRV 198 Query: 181 WKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQKDQLVTQLHWQENGPTF 240 WKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQKDQLVTQLHWQENGPTF Sbjct: 199 WKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQKDQLVTQLHWQENGPTF 258 Query: 241 SSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGH 300 SSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGH Sbjct: 259 SSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGH 318 Query: 301 EVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEKGRGPE 360 EVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEKGRGPE Sbjct: 319 EVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEKGRGPE 378 Query: 361 LLGSHETALFSVAVDSRCQLHLLPSRRSV 389 LLGSHETALFSVAVDSRCQLHLLPSRRSV Sbjct: 379 LLGSHETALFSVAVDSRCQLHLLPSRRSV 407 >5NNZ-B nrPDB Length = 415 Score = 218 bits (554), Expect = 5e-57, Method: Composition-based stats. Identities = 57/265 (21%), Positives = 105/265 (39%), Gaps = 59/265 (22%) Query: 158 KVVC--FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDG-KLVTVG 214 ++VC FN +TL+ATG D ++W + + E+V + H EI L+ G +++T Sbjct: 179 EIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGS 238 Query: 215 RDLKASVWQKD--QLVTQL--HWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIP 270 D VW D + V L H E SS + + C +L Sbjct: 239 FDHTVVVWDADTGRKVNILIGHCAE----ISSASFNWD-CSLILTGSMDKTCKL------ 287 Query: 271 HKRLRQPPPCYLTAWDGSNFLPLRTKSCGHE---VVSCLDVSESGTFLGLGTVTGSVAIY 327 WD +N + T + GH+ + SC D +G + + G+ I+ Sbjct: 288 --------------WDATNGKCVATLT-GHDDEILDSCFDY--TGKLIATASADGTARIF 330 Query: 328 IAFSLQCLYYVREAHGIVVTDVAFLP-------------------EKGRGPELLGSHETA 368 A + +C+ + E H ++ ++F P + G+ ++L H Sbjct: 331 SAATRKCIAKL-EGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDE 389 Query: 369 LFSVAVDSRCQLHLLPSR-RSVPVW 392 +FS A + + + + S+ + +W Sbjct: 390 IFSCAFNYKGNIVITGSKDNTCRIW 414 >5OPT-p nrPDB Length = 318 Score = 160 bits (404), Expect = 1e-39, Method: Composition-based stats. Identities = 37/161 (22%), Positives = 67/161 (41%), Gaps = 24/161 (14%) Query: 165 DNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDLKASVWQ 223 + L+ +GG D V+VW + S + + K H I + + PDG L + +D A +W Sbjct: 165 ETPLIVSGGWDNLVKVWDIASGRLLTDLKGHTNYITSVTVSPDGSLCASSDKDGVARLWD 224 Query: 224 --KDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQI----------PH 271 K + ++++ +P RY C + G+R+F ++ Sbjct: 225 LTKGEALSEMAAGAPINQICFSPNRYWMCAATE-----KGIRIFDLENKDVIVELAPEAQ 279 Query: 272 KRLRQPPPCYLTAW--DGSNFLPLRTKSCGHEVVSCLDVSE 310 ++ ++ P C AW DG+ T + V+ VSE Sbjct: 280 QKSKKTPECMSIAWSADGNTLYSGYTDN----VIRVWSVSE 316 Score = 70.1 bits (170), Expect = 2e-12, Method: Composition-based stats. Identities = 34/219 (15%), Positives = 67/219 (30%), Gaps = 30/219 (13%) Query: 138 ELRVENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEG 197 E R+E A +D V +++ + D +R+W + + +F H Sbjct: 60 ERRLEGHSAFVSD---------VALSNNGDFAVSASWDHSLRLWNLQTGVCQHKFLGHTK 110 Query: 198 EIEDLALGPDGKLV-TVGRDLKASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVP 256 ++ + PD + + + GRD VW E T + P Sbjct: 111 DVLSVTFSPDNRQIVSGGRDNALRVWNVK--------GECLHTLGRGAHTDWVSCVRFSP 162 Query: 257 DQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLG 316 L + + WD ++ L ++ + VS G+ Sbjct: 163 SLETPLIV----------SGGWDNLVKVWDIASGRLLTDLKGHTNYITSVTVSPDGSLCA 212 Query: 317 LGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEK 355 G ++ + L + A G + + F P + Sbjct: 213 SSDKDGVARLWDLTKGEALSEM--AAGAPINQICFSPNR 249 >4V8M-A7 nrPDB Length = 318 Score = 149 bits (375), Expect = 3e-36, Method: Composition-based stats. Identities = 38/163 (23%), Positives = 68/163 (41%), Gaps = 24/163 (14%) Query: 165 DNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDLKASVWQ 223 D ++ +GG D V+VW + + V + K H + + + PDG L + +D A +W Sbjct: 165 DAPVIVSGGWDNLVKVWDLATGRLVTDLKGHTNYVTSVTVSPDGSLCASSDKDGVARLWD 224 Query: 224 --KDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIP---------HK 272 K + ++++ +P RY C + G+R+F ++ H+ Sbjct: 225 LTKGEALSEMAAGAPINQICFSPNRYWMCAATE-----KGIRIFDLENKDIIVELAPEHQ 279 Query: 273 RLRQ-PPPCYLTAW--DGSNFLPLRTKSCGHEVVSCLDVSESG 312 ++ P C AW DGS T + V+ VSE+ Sbjct: 280 GSKKIVPECVSIAWSADGSTLYSGYTDN----VIRVWGVSENA 318 Score = 77.1 bits (188), Expect = 1e-14, Method: Composition-based stats. Identities = 31/197 (15%), Positives = 63/197 (31%), Gaps = 21/197 (10%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDLK 218 V +++ + D +R+W + + + +F H ++ +A PD + + + GRD Sbjct: 73 VALSNNGNFAVSASWDHSLRLWNLQNGQCQYKFLGHTKDVLSVAFSPDNRQIVSGGRDNA 132 Query: 219 ASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPP 278 VW E T S + P A + + Sbjct: 133 LRVWNVK--------GECMHTLSRGAHTDWVSCVRFSPSLDAPVIV----------SGGW 174 Query: 279 PCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYV 338 + WD + + V+ + VS G+ G ++ + L + Sbjct: 175 DNLVKVWDLATGRLVTDLKGHTNYVTSVTVSPDGSLCASSDKDGVARLWDLTKGEALSEM 234 Query: 339 REAHGIVVTDVAFLPEK 355 A G + + F P + Sbjct: 235 --AAGAPINQICFSPNR 249 Score = 34.7 bits (78), Expect = 0.076, Method: Composition-based stats. Identities = 35/176 (19%), Positives = 56/176 (31%), Gaps = 26/176 (14%) Query: 243 TPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEV 302 T +R ++ + L P + + S LP R Sbjct: 10 TGHRGWVTSLACPQTPETATKVVSTSRDKTLLSWGPNPDRHSSECSYGLPDRRLEGHSAF 69 Query: 303 VSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPE-------- 354 VS + +S +G F + S+ ++ + QC Y H V VAF P+ Sbjct: 70 VSDVALSNNGNFAVSASWDHSLRLWNLQNGQCQYKFL-GHTKDVLSVAFSPDNRQIVSGG 128 Query: 355 ----------KGRGPELL--GSHETAL----FSVAVDSRCQLHLLPSRRSVPVWLL 394 KG L G+H + FS ++D+ + V VW L Sbjct: 129 RDNALRVWNVKGECMHTLSRGAHTDWVSCVRFSPSLDAPV-IVSGGWDNLVKVWDL 183 >5MZH-A nrPDB Length = 452 Score = 145 bits (365), Expect = 4e-35, Method: Composition-based stats. Identities = 50/258 (19%), Positives = 86/258 (33%), Gaps = 45/258 (17%) Query: 158 KVVC--FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVG 214 ++VC FN +T++ATG D ++W V + ++ H EI L G L+ T Sbjct: 181 EIVCLSFNPQSTIIATGSMDNTAKLWDVETGQERATLAGHRAEIVSLGFNTGGDLIVTGS 240 Query: 215 RDLKASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRL 274 D + +W + SST + Y A Sbjct: 241 FDHDSRLWDVRTGQCVHVLSGHRGEVSSTQFNY-AGTLVVSGSID--------------- 284 Query: 275 RQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQC 334 C WD + L K + V + +GT + + GS +Y + C Sbjct: 285 -----CTSRLWDVRSGRCLSVKQGHTDEVLDVAFDAAGTKMVSASADGSARLYHTLTGVC 339 Query: 335 LYYVREAHGIVVTDVAFLPE-------------------KGRGPELLGSHETALFSVAVD 375 + + H ++ VAF P+ G ++L H +FS A + Sbjct: 340 QHTLV-GHEGEISKVAFNPQGTRLITASSDKTCRLWDCDTGECLQVLEGHTDEIFSCAFN 398 Query: 376 SRCQLHLLPSR-RSVPVW 392 + S+ + +W Sbjct: 399 YEGDFIITGSKDNTCRIW 416 Score = 30.1 bits (66), Expect = 2.1, Method: Composition-based stats. Identities = 8/34 (23%), Positives = 15/34 (44%), Gaps = 1/34 (2%) Query: 360 ELLGSHETALFSVAVDSRCQLHLLPS-RRSVPVW 392 ++L +H L + A + + S R+ VW Sbjct: 88 KVLRAHILPLTNCAFNKSGDRFITGSYDRTCKVW 121 >4V6W-Ag nrPDB Length = 318 Score = 131 bits (330), Expect = 5e-31, Method: Composition-based stats. Identities = 36/163 (22%), Positives = 58/163 (35%), Gaps = 18/163 (11%) Query: 163 NHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVT-VGRDLKASV 221 NH N ++ + G D V+VW + + + H G + + + PDG L T G+D KA + Sbjct: 160 NHSNPIIVSCGWDRTVKVWNLANCKLKNNHHGHNGYLNTVTVSPDGSLCTSGGKDSKALL 219 Query: 222 WQKD---QLVTQLHWQENGPTFSSTPYRYQACRF------GQVPDQPAGLRLFTVQIPHK 272 W + L T H + +P RY C + ++ Sbjct: 220 WDLNDGKNLYTLEH-NDIINALCFSPNRYWLCVAYGPSIKIWDLACKKTVEELRPEVVSP 278 Query: 273 RLR-QPPPCYLTAW--DGSNFLPLRTKSCGHEVVSCLDVSESG 312 + P C AW DG + + + VS S Sbjct: 279 TSKADQPQCLSLAWSTDGQTLFAGYSDNT----IRVWQVSVSA 317 Score = 66.7 bits (161), Expect = 2e-11, Method: Composition-based stats. Identities = 32/261 (12%), Positives = 78/261 (29%), Gaps = 47/261 (18%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDLK 218 V + D +G D +R+W + + + F+ H ++ +A D + + + RD Sbjct: 70 VVLSSDGNYALSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKT 129 Query: 219 ASVWQ--KDQLVTQLHWQ--ENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRL 274 +W + T + +P ++++ + + Sbjct: 130 IKLWNTLAECKFTIQEDGHTDWVSCVRFSPNHSNP--IIVSCGWDRTVKVWNLANCKLKN 187 Query: 275 RQ----------------------PPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESG 312 WD ++ L T +++++ L S + Sbjct: 188 NHHGHNGYLNTVTVSPDGSLCTSGGKDSKALLWDLNDGKNLYTLEH-NDIINALCFSPNR 246 Query: 313 TFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEKGRGPELLGSHETALFSV 372 +L + S+ I+ + + +R V ++ + S+ Sbjct: 247 YWLCVAYGP-SIKIWDLACKKTVEELRP----EVVSPTSKADQPQCL-----------SL 290 Query: 373 AVDSRCQLHLLP-SRRSVPVW 392 A + Q S ++ VW Sbjct: 291 AWSTDGQTLFAGYSDNTIRVW 311 Score = 29.3 bits (64), Expect = 2.9, Method: Composition-based stats. Identities = 10/44 (22%), Positives = 19/44 (43%), Gaps = 1/44 (2%) Query: 356 GRGPELLGSHETALFSVAVDSRCQLHLLPSR-RSVPVWLLLLLC 398 G+ H + SVA + + + SR +++ +W L C Sbjct: 96 GKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLAEC 139 >6G51-g nrPDB Length = 317 Score = 124 bits (311), Expect = 7e-29, Method: Composition-based stats. Identities = 33/164 (20%), Positives = 62/164 (37%), Gaps = 26/164 (15%) Query: 163 NHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDLKASV 221 N N ++ + G D V+VW + + + H G + + + PDG L + G+D +A + Sbjct: 159 NSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAML 218 Query: 222 WQKDQL--VTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQ----------- 268 W ++ + L + +P RY C ++++ ++ Sbjct: 219 WDLNEGKHLYTLDGGDIINALCFSPNRYWLCAAT-----GPSIKIWDLEGKIIVDELKQE 273 Query: 269 -IPHKRLRQPPPCYLTAW--DGSNFLPLRTKSCGHEVVSCLDVS 309 I +PP C AW DG T + +V V+ Sbjct: 274 VISTSSKAEPPQCTSLAWSADGQTLFAGYTDN----LVRVWQVT 313 Score = 64.7 bits (156), Expect = 7e-11, Method: Composition-based stats. Identities = 30/213 (14%), Positives = 63/213 (29%), Gaps = 34/213 (15%) Query: 148 QTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPD 207 + F SD V + D +G DG +R+W + + F H ++ +A D Sbjct: 62 HSHFVSD-----VVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSD 116 Query: 208 GKLV-TVGRDLKASVWQK----DQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGL 262 + + + RD +W V E +P + Sbjct: 117 NRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNP--IIVSCGWDKLV 174 Query: 263 RLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTG 322 +++ + + G ++ + VS G+ G G Sbjct: 175 KVWNLANCKLKTNHI---------GHTGY-----------LNTVTVSPDGSLCASGGKDG 214 Query: 323 SVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEK 355 ++ + LY + ++ + F P + Sbjct: 215 QAMLWDLNEGKHLYTLDGGD--IINALCFSPNR 245 Score = 35.5 bits (80), Expect = 0.043, Method: Composition-based stats. Identities = 27/176 (15%), Positives = 51/176 (28%), Gaps = 20/176 (11%) Query: 183 VPSLEKVLEFKAHEGEIEDLALGPD--GKLVTVGRDLKASVWQKDQLVTQLHWQENGPTF 240 + K H G + +A P +++ RD +W+ + T Sbjct: 2 TEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDET----------- 50 Query: 241 SSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGH 300 Y + + L L WD + R Sbjct: 51 -----NYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHT 105 Query: 301 EVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYVR-EAHGIVVTDVAFLPEK 355 + V + S + G+ ++ ++ + C Y V+ E+H V+ V F P Sbjct: 106 KDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGV-CKYTVQDESHSEWVSCVRFSPNS 160 Score = 30.9 bits (68), Expect = 1.0, Method: Composition-based stats. Identities = 25/155 (16%), Positives = 49/155 (31%), Gaps = 31/155 (20%) Query: 245 YRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVS 304 + + P P + + R + LT + + +P R VS Sbjct: 14 HNGWVTQIATTPQFP------DMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVS 67 Query: 305 CLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEKGRGPELLGS 364 + +S G F G+ G++ ++ + G Sbjct: 68 DVVISSDGQFALSGSWDGTLRLWDLTT------------------------GTTTRRFVG 103 Query: 365 HETALFSVAVDSRCQLHLLPSR-RSVPVWLLLLLC 398 H + SVA S + + SR +++ +W L +C Sbjct: 104 HTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVC 138 >3DM0-A nrPDB Length = 694 Score = 113 bits (282), Expect = 2e-25, Method: Composition-based stats. Identities = 34/173 (19%), Positives = 65/173 (37%), Gaps = 15/173 (8%) Query: 162 FNHDN--TLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDLK 218 F+ + + + D V+VW + + + H G + +A+ PDG L + G+D Sbjct: 525 FSPNTLQPTIVSASWDKTVKVWNLSNCKLRSTLAGHTGYVSTVAVSPDGSLCASGGKDGV 584 Query: 219 ASVWQK--DQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQ 276 +W + + L +P RY C + G++++ ++ Sbjct: 585 VLLWDLAEGKKLYSLEANSVIHALCFSPNRYWLCAATE-----HGIKIWDLESKSIVEDL 639 Query: 277 PPPCYLTAWDGSNFLPLRTKSCGHEVVSC--LDVSESGTFLGLGTVTGSVAIY 327 A N P TK +V+ C L+ S G+ L G G + ++ Sbjct: 640 KVDLKAEAEKADNSGPAATK---RKVIYCTSLNWSADGSTLFSGYTDGVIRVW 689 Score = 67.4 bits (163), Expect = 1e-11, Method: Composition-based stats. Identities = 37/203 (18%), Positives = 67/203 (33%), Gaps = 31/203 (15%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDLK 218 V + D +G DG +R+W + + F H ++ +A D + + + RD Sbjct: 436 VVLSSDGQFALSGSWDGELRLWDLAAGVSTRRFVGHTKDVLSVAFSLDNRQIVSASRDRT 495 Query: 219 ASVWQK--DQLVTQLHWQEN----GPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHK 272 +W + T E +P Q +++ Sbjct: 496 IKLWNTLGECKYTISEGGEGHRDWVSCVRFSPNTLQP--TIVSASWDKTVKV-------- 545 Query: 273 RLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSL 332 W+ SN T + VS + VS G+ G G V ++ Sbjct: 546 ------------WNLSNCKLRSTLAGHTGYVSTVAVSPDGSLCASGGKDGVVLLWDLAEG 593 Query: 333 QCLYYVREAHGIVVTDVAFLPEK 355 + LY + EA+ V+ + F P + Sbjct: 594 KKLYSL-EANS-VIHALCFSPNR 614 >5XYI-g nrPDB Length = 335 Score = 92.9 bits (229), Expect = 2e-19, Method: Composition-based stats. Identities = 35/159 (22%), Positives = 58/159 (36%), Gaps = 19/159 (11%) Query: 168 LLATGGTDGYVRVWKVPSL-EKVLEFKAHEGEIEDLALGPDGK-LVTVGRDLKASVWQKD 225 ++A G DG V +W + + + EFKAH+G + PDGK ++T G D K +W + Sbjct: 181 VIAVGCWDGKVYIWSIEKEAKLIKEFKAHDGRCTSVDFTPDGKWVITGGSDRKVVMWLTE 240 Query: 226 QLVTQLHWQENGP--TFSSTPYRYQACRFGQVP------DQPAGLRLFTVQIPHKRLR-- 275 + + P ++ P + C + L H+ R Sbjct: 241 NGAKTISFTAPSPVHAVAACPTQAWICAATYEGIAVWDIGAKQQIDLVQPNFKHEGKRNA 300 Query: 276 -QPPPCYLTAW--DGSNFLPLRTKSCGHEVVSCLDVSES 311 + P C AW DGS + +V + Sbjct: 301 GRTPDCTCLAWAADGSVLYSGYNDGS----IRAWEVKSA 335 Score = 55.9 bits (133), Expect = 3e-08, Method: Composition-based stats. Identities = 17/87 (19%), Positives = 38/87 (43%), Gaps = 2/87 (2%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGP-DGKLVTVGRDLK 218 V + D + L T D +R+W + + F H+ ++ + P + ++++VGRD + Sbjct: 86 VSLSRDASHLLTSSWDSTLRLWDLSTRTTKKLFLGHKKDVLGVTFSPCNRRIISVGRDNQ 145 Query: 219 ASVWQ-KDQLVTQLHWQENGPTFSSTP 244 +W + +L + + P Sbjct: 146 VKIWNILGENKAELQCSSWVTSVACAP 172 Score = 40.1 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 39/203 (19%), Positives = 60/203 (29%), Gaps = 34/203 (16%) Query: 184 PSLEKVLEFKAHEGEIEDLALGPDGK-LVTVGRDLKASVWQKDQLVTQLHWQENG----- 237 F H IE + + + LV+ RD A VW+ ++ TQ W Sbjct: 21 AHFAPRATFVGHNAAIESIEIDNEHNYLVSASRDKSALVWKLNR--TQEQWATPFTRLIG 78 Query: 238 -PTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLR-----------QPPPC----- 280 F S + + LRL+ + + PC Sbjct: 79 HNHFVSDVSLSRDASHLLTSSWDSTLRLWDLSTRTTKKLFLGHKKDVLGVTFSPCNRRII 138 Query: 281 ------YLTAWD--GSNFLPLRTKSCGHEVVSCLDVSESGTF-LGLGTVTGSVAIYIAFS 331 + W+ G N L+ S V E+ + +G G V I+ Sbjct: 139 SVGRDNQVKIWNILGENKAELQCSSWVTSVACAPMADETSPLVIAVGCWDGKVYIWSIEK 198 Query: 332 LQCLYYVREAHGIVVTDVAFLPE 354 L +AH T V F P+ Sbjct: 199 EAKLIKEFKAHDGRCTSVDFTPD 221 >5M25-A nrPDB Length = 434 Score = 92.9 bits (229), Expect = 2e-19, Method: Composition-based stats. Identities = 40/257 (15%), Positives = 77/257 (29%), Gaps = 45/257 (17%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK-LVTVGRDLKAS 220 F+ + LA+ D +++W + H+ I D+A D LV+ D Sbjct: 153 FSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLK 212 Query: 221 VWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPC 280 +W + + + Q+ +R+ Sbjct: 213 IWDVSSGKCLKTLKGHSNYVFCCNFNPQS-NLIVSGSFDESVRI---------------- 255 Query: 281 YLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYVRE 340 WD L+T + VS + + G+ + + G I+ S QCL + + Sbjct: 256 ----WDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLID 311 Query: 341 AHGIVVTDVAFLP-------------------EKGRGPELLGSHETALFSVAVDSR---C 378 V+ V F P KG+ + H+ + + + Sbjct: 312 DDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGG 371 Query: 379 QLHLLPSR-RSVPVWLL 394 + + S V +W L Sbjct: 372 KWIVSGSEDNLVYIWNL 388 Score = 84.0 bits (206), Expect = 1e-16, Method: Composition-based stats. Identities = 42/222 (18%), Positives = 75/222 (33%), Gaps = 31/222 (13%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGR-DLK 218 V ++ D+ LL + D +++W V S + + K H + P L+ G D Sbjct: 193 VAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDES 252 Query: 219 ASVWQ------------KDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFT 266 +W V+ +H+ +G S+ Y CR L Sbjct: 253 VRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYD-GLCRIWDTASGQCLKTLID 311 Query: 267 VQIPHKRLRQPPP-----------CYLTAWDGSNFLPLRT----KSCGHEVVSCLDVSES 311 P + P L WD S L+T K+ + + + V+ Sbjct: 312 DDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVT-G 370 Query: 312 GTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLP 353 G ++ G+ V I+ + + + + + H VV A P Sbjct: 371 GKWIVSGSEDNLVYIWNLQTKEIVQKL-QGHTDVVISTACHP 411 Score = 48.6 bits (114), Expect = 5e-06, Method: Composition-based stats. Identities = 12/63 (19%), Positives = 24/63 (38%), Gaps = 3/63 (4%) Query: 166 NTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVG---RDLKASVW 222 + +G D V +W + + E V + + H + A P ++ D +W Sbjct: 371 GKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 430 Query: 223 QKD 225 + D Sbjct: 431 KSD 433 >2H9P-A nrPDB Length = 329 Score = 92.9 bits (229), Expect = 2e-19, Method: Composition-based stats. Identities = 40/257 (15%), Positives = 77/257 (29%), Gaps = 45/257 (17%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK-LVTVGRDLKAS 220 F+ + LA+ D +++W + H+ I D+A D LV+ D Sbjct: 48 FSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLK 107 Query: 221 VWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPC 280 +W + + + Q+ +R+ Sbjct: 108 IWDVSSGKCLKTLKGHSNYVFCCNFNPQS-NLIVSGSFDESVRI---------------- 150 Query: 281 YLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYVRE 340 WD L+T + VS + + G+ + + G I+ S QCL + + Sbjct: 151 ----WDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLID 206 Query: 341 AHGIVVTDVAFLP-------------------EKGRGPELLGSHETALFSVAVDSR---C 378 V+ V F P KG+ + H+ + + + Sbjct: 207 DDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGG 266 Query: 379 QLHLLPSR-RSVPVWLL 394 + + S V +W L Sbjct: 267 KWIVSGSEDNLVYIWNL 283 Score = 84.0 bits (206), Expect = 1e-16, Method: Composition-based stats. Identities = 42/222 (18%), Positives = 75/222 (33%), Gaps = 31/222 (13%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGR-DLK 218 V ++ D+ LL + D +++W V S + + K H + P L+ G D Sbjct: 88 VAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDES 147 Query: 219 ASVWQ------------KDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFT 266 +W V+ +H+ +G S+ Y CR L Sbjct: 148 VRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYD-GLCRIWDTASGQCLKTLID 206 Query: 267 VQIPHKRLRQPPP-----------CYLTAWDGSNFLPLRT----KSCGHEVVSCLDVSES 311 P + P L WD S L+T K+ + + + V+ Sbjct: 207 DDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVT-G 265 Query: 312 GTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLP 353 G ++ G+ V I+ + + + + + H VV A P Sbjct: 266 GKWIVSGSEDNLVYIWNLQTKEIVQKL-QGHTDVVISTACHP 306 Score = 48.6 bits (114), Expect = 5e-06, Method: Composition-based stats. Identities = 12/63 (19%), Positives = 24/63 (38%), Gaps = 3/63 (4%) Query: 166 NTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVG---RDLKASVW 222 + +G D V +W + + E V + + H + A P ++ D +W Sbjct: 266 GKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 325 Query: 223 QKD 225 + D Sbjct: 326 KSD 328 >4BTS-AR nrPDB Length = 343 Score = 91.7 bits (226), Expect = 6e-19, Method: Composition-based stats. Identities = 33/168 (19%), Positives = 55/168 (32%), Gaps = 32/168 (19%) Query: 167 TLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDLKASVWQKD 225 A+ G DG ++VW + + FKAHE + L++ P+GK + T G+D K +W Sbjct: 185 PYFASVGWDGRLKVWNT-NFQIRYTFKAHESNVNHLSISPNGKYIATGGKDKKLLIWDIL 243 Query: 226 QLV---TQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHK---------- 272 L + + P G+++F + K Sbjct: 244 NLTYPQREFDAGSTINQIAFNPKLQWVAVGT-----DQGVKIFNLMTQSKAPVCTIEAEP 298 Query: 273 ------RLRQPPPCYLTAWD--GSNFLPLRTKSCGHEVVSCLDVSESG 312 + + P C AW+ G T V+ S Sbjct: 299 ITKAEGQKGKNPQCTSLAWNALGKKLFAGFTDG----VIRTFSFETSA 342 Score = 65.5 bits (158), Expect = 4e-11, Method: Composition-based stats. Identities = 35/205 (17%), Positives = 70/205 (34%), Gaps = 36/205 (17%) Query: 163 NHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDLKASV 221 + +N + D +R+W + + F H+ E+ +A PD + + + G + + + Sbjct: 85 SQENCFAISSSWDKTLRLWDLRTGTTYKRFVGHQSEVYSVAFSPDNRQILSAGAEREIKL 144 Query: 222 WQ-----KDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQ 276 W K + + + +P ++ +K Sbjct: 145 WNILGECKFSSAEKENHSDWVSCVRYSP---------------------IMKSANKVQPF 183 Query: 277 PPPCYLTAWDG------SNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAF 330 P WDG +NF T V+ L +S +G ++ G + I+ Sbjct: 184 APYFASVGWDGRLKVWNTNFQIRYTFKAHESNVNHLSISPNGKYIATGGKDKKLLIWDIL 243 Query: 331 SLQCLYYVREAHGI-VVTDVAFLPE 354 +L Y RE + +AF P+ Sbjct: 244 NLT--YPQREFDAGSTINQIAFNPK 266 >1VYH-C nrPDB Length = 410 Score = 90.9 bits (224), Expect = 9e-19, Method: Composition-based stats. Identities = 41/282 (14%), Positives = 93/282 (32%), Gaps = 70/282 (24%) Query: 155 PLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TV 213 P+ +V+ F+ +++ + D ++VW + + K H ++D++ GKL+ + Sbjct: 110 PVTRVI-FHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASC 168 Query: 214 GRDLKASVWQ---KDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIP 270 D+ +W + + T N + S P + +++ Sbjct: 169 SADMTIKLWDFQGFECIRTMHGHDHNVSSVSIMPNGDHIVSA----SRDKTIKM------ 218 Query: 271 HKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAF 330 W+ ++T + E V + ++ GT + + +V +++ Sbjct: 219 --------------WEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVA 264 Query: 331 SLQCLYYVREAHGIVVTDVAFLPE------------------------------------ 354 + +C +RE H VV +++ PE Sbjct: 265 TKECKAELRE-HRHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMW 323 Query: 355 ---KGRGPELLGSHETALFSVAVDSRCQLHLL-PSRRSVPVW 392 G L H+ + V S + L +++ VW Sbjct: 324 DVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVW 365 Score = 85.2 bits (209), Expect = 5e-17, Method: Composition-based stats. Identities = 45/274 (16%), Positives = 91/274 (33%), Gaps = 50/274 (18%) Query: 153 SDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK-LV 211 +D +Q + F+H LLA+ D +++W E + H+ + +++ P+G +V Sbjct: 150 TDSVQDI-SFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVSIMPNGDHIV 208 Query: 212 TVGRDLKASVWQKDQLVTQLHWQENGPTFSSTPYRYQA--------CRFGQVPDQPAGLR 263 + RD +W+ + T +R +R Sbjct: 209 SASRDKTIKMWEVQTGYCVK---------TFTGHREWVRMVRPNQDGTLIASCSNDQTVR 259 Query: 264 LFTVQIPHKRL-----RQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLG 318 ++ V + R C +W + +++ G E + G FL G Sbjct: 260 VWVVATKECKAELREHRHVVEC--ISWAPESSYSSISEATGSETKKS---GKPGPFLLSG 314 Query: 319 TVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLP-------------------EKGRGP 359 + ++ ++ + CL + H V V F + R Sbjct: 315 SRDKTIKMWDVSTGMCLMTLV-GHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCM 373 Query: 360 ELLGSHETALFSVAVDSRCQLHLLPS-RRSVPVW 392 + L +HE + S+ + S ++V VW Sbjct: 374 KTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 407 Score = 72.1 bits (175), Expect = 4e-13, Method: Composition-based stats. Identities = 35/222 (15%), Positives = 69/222 (31%), Gaps = 25/222 (11%) Query: 142 ENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIED 201 + + ++T D V + + + D +++W+V + V F H + Sbjct: 180 QGFECIRTMHGHDHNVSSVSIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRM 239 Query: 202 LALGPDGKLV-TVGRDLKASVW---QKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPD 257 + DG L+ + D VW K+ + S P + Sbjct: 240 VRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHRHVVECISWAPESSYSSISEATGS 299 Query: 258 QPAGLRLFTVQIPHKRLRQPPPCYLTA--------WDGSNFLPLRTKSCGHEVVSCLDVS 309 + + +P P L+ WD S + L T V + Sbjct: 300 ETK------------KSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFH 347 Query: 310 ESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAF 351 G F+ ++ ++ + +C+ AH VT + F Sbjct: 348 SGGKFILSCADDKTLRVWDYKNKRCM-KTLNAHEHFVTSLDF 388 Score = 28.2 bits (61), Expect = 6.7, Method: Composition-based stats. Identities = 7/21 (33%), Positives = 11/21 (52%) Query: 162 FNHDNTLLATGGTDGYVRVWK 182 F+ + TG D V+VW+ Sbjct: 388 FHKTAPYVVTGSVDQTVKVWE 408 >6HQA-B nrPDB Length = 722 Score = 90.9 bits (224), Expect = 1e-18, Method: Composition-based stats. Identities = 31/131 (23%), Positives = 53/131 (40%), Gaps = 11/131 (8%) Query: 156 LQKVVC--FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK-LVT 212 L V C F+ ++T L TG +D R+W + E V F H G I LA+ PDG+ L + Sbjct: 537 LNDVDCVEFHPNSTYLFTGSSDKTARMWDIARGECVRVFMGHSGAINCLAVSPDGRWLAS 596 Query: 213 VGRDLKASVWQ--KDQLVTQL--HWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQ 268 G D +W + + + H + + + + + G +R++ V+ Sbjct: 597 AGEDSVVCLWDISTGRRIKAMRGHGRSSIYSLAFSREGTVLVSTG----ADNSVRVWDVK 652 Query: 269 IPHKRLRQPPP 279 P Sbjct: 653 KNTNSPSAQPE 663 Score = 88.2 bits (217), Expect = 6e-18, Method: Composition-based stats. Identities = 42/238 (17%), Positives = 74/238 (31%), Gaps = 56/238 (23%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK-LVTVGRDLKAS 220 F+ DN L + D VR+W + + ++ +K H + D+ P G T D A Sbjct: 461 FSPDNRYLISCSEDKTVRLWSLDTYTCLVSYKGHSSSVWDVKFSPMGHYFATASHDQTAR 520 Query: 221 VWQKDQLVTQL----HWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQ 276 +W D + H + P + R+ Sbjct: 521 LWSCDHIYPLRIFAGHLND-VDCVEFHPNS----TYLFTGSSDKTARM------------ 563 Query: 277 PPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLY 336 WD + +R ++CL VS G +L V CL+ Sbjct: 564 --------WDIARGECVRVFMGHSGAINCLAVSPDGRWLASAGEDSVV---------CLW 606 Query: 337 YVREAHGIVVTDVAFLPEKGRGPELLGSH-ETALFSVAVDSRCQLHL-LPSRRSVPVW 392 + GR + + H ++++S+A + + + SV VW Sbjct: 607 DI---------------STGRRIKAMRGHGRSSIYSLAFSREGTVLVSTGADNSVRVW 649 >6HHQ-h nrPDB Length = 319 Score = 90.6 bits (223), Expect = 1e-18, Method: Composition-based stats. Identities = 31/162 (19%), Positives = 58/162 (35%), Gaps = 25/162 (15%) Query: 163 NHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDLKASV 221 + D+ + + G D V+ W + + +F H I L PDG L+ + G+D + + Sbjct: 163 DDDSVTIISAGNDKMVKAWNLNQFQIEADFIGHNSNINTLTASPDGTLIASAGKDGEIML 222 Query: 222 WQ--KDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTV-----------Q 268 W + + L Q+ + + +P RY G+++F++ + Sbjct: 223 WNLAAKKAMYTLSAQDEVFSLAFSPNRYWLAAATAT-----GIKVFSLDPQYLVDDLRPE 277 Query: 269 IPHKRLRQPPPCYLTAW--DGSNFLPLRTKSCGHEVVSCLDV 308 P AW DG T + V+ V Sbjct: 278 FAGYSKAAEPHAVSLAWSADGQTLFAGYTDN----VIRVWQV 315 Score = 64.7 bits (156), Expect = 6e-11, Method: Composition-based stats. Identities = 29/194 (14%), Positives = 62/194 (31%), Gaps = 23/194 (11%) Query: 165 DNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKL-VTVGRDLKASVW- 222 D + D +R+W V + E F H+ ++ + + + ++ RD VW Sbjct: 76 DGAYALSASWDKTLRLWDVATGETYQRFVGHKSDVMSVDIDKKASMIISGSRDKTIKVWT 135 Query: 223 -QKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCY 281 + L T L + P + + + Sbjct: 136 IKGQCLATLLGHNDWVSQVRVVPNE---------KADDDSVTIISAGNDK---------M 177 Query: 282 LTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYVREA 341 + AW+ + F + ++ L S GT + G + ++ + + +Y + Sbjct: 178 VKAWNLNQFQIEADFIGHNSNINTLTASPDGTLIASAGKDGEIMLWNLAAKKAMYTLSA- 236 Query: 342 HGIVVTDVAFLPEK 355 V +AF P + Sbjct: 237 -QDEVFSLAFSPNR 249 Score = 31.6 bits (70), Expect = 0.66, Method: Composition-based stats. Identities = 10/50 (20%), Positives = 25/50 (50%), Gaps = 1/50 (2%) Query: 355 KGRGPELLGSHETALFSVAVDSRCQLHLLPSR-RSVPVWLLLLLCVGLII 403 G + H++ + SV +D + + + SR +++ VW + C+ ++ Sbjct: 96 TGETYQRFVGHKSDVMSVDIDKKASMIISGSRDKTIKVWTIKGQCLATLL 145 >6MZM-G nrPDB Length = 800 Score = 89.4 bits (220), Expect = 3e-18, Method: Composition-based stats. Identities = 44/238 (18%), Positives = 74/238 (31%), Gaps = 57/238 (23%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDG-KLVTVGRDLKAS 220 F+ D L + DG VR+W + + ++ +K H + D P G V+ G D A Sbjct: 551 FSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVAR 610 Query: 221 VWQKD-----QLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLR 275 +W D ++ N F + +RL Sbjct: 611 LWATDHYQPLRIFAGHLADVNCTRFHPNSN------YVATGSADRTVRL----------- 653 Query: 276 QPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCL 335 WD N +R + + L S +G FL G G V ++ Sbjct: 654 ---------WDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDI------ 698 Query: 336 YYVREAHGIVVTDVAFLPEKGRGPELLGSHETALFSVAVDSRCQLHLLPS-RRSVPVW 392 HG++V + L H + S+ ++ S +V +W Sbjct: 699 -----GHGLMVGE-------------LKGHTDTVCSLRFSRDGEILASGSMDNTVRLW 738 Score = 82.5 bits (202), Expect = 3e-16, Method: Composition-based stats. Identities = 28/114 (24%), Positives = 45/114 (39%), Gaps = 4/114 (3%) Query: 156 LQKVVC--FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK-LVT 212 L V C F+ ++ +ATG D VR+W V + V F H+G I L P+G+ L T Sbjct: 627 LADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLAT 686 Query: 213 VGRDLKASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFT 266 D + +W + + + T S + +RL+ Sbjct: 687 GATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDG-EILASGSMDNTVRLWD 739 Score = 32.8 bits (73), Expect = 0.33, Method: Composition-based stats. Identities = 11/29 (37%), Positives = 15/29 (51%), Gaps = 3/29 (10%) Query: 158 KVVC---FNHDNTLLATGGTDGYVRVWKV 183 VC F+ D +LA+G D VR+W Sbjct: 712 DTVCSLRFSRDGEILASGSMDNTVRLWDA 740 >6F3T-A nrPDB Length = 608 Score = 89.4 bits (220), Expect = 3e-18, Method: Composition-based stats. Identities = 44/238 (18%), Positives = 74/238 (31%), Gaps = 57/238 (23%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDG-KLVTVGRDLKAS 220 F+ D L + DG VR+W + + ++ +K H + D P G V+ G D A Sbjct: 359 FSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVAR 418 Query: 221 VWQKD-----QLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLR 275 +W D ++ N F + +RL Sbjct: 419 LWATDHYQPLRIFAGHLADVNCTRFHPNSN------YVATGSADRTVRL----------- 461 Query: 276 QPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCL 335 WD N +R + + L S +G FL G G V ++ Sbjct: 462 ---------WDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDI------ 506 Query: 336 YYVREAHGIVVTDVAFLPEKGRGPELLGSHETALFSVAVDSRCQLHLLPS-RRSVPVW 392 HG++V + L H + S+ ++ S +V +W Sbjct: 507 -----GHGLMVGE-------------LKGHTDTVCSLRFSRDGEILASGSMDNTVRLW 546 Score = 82.5 bits (202), Expect = 3e-16, Method: Composition-based stats. Identities = 28/114 (24%), Positives = 45/114 (39%), Gaps = 4/114 (3%) Query: 156 LQKVVC--FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK-LVT 212 L V C F+ ++ +ATG D VR+W V + V F H+G I L P+G+ L T Sbjct: 435 LADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLAT 494 Query: 213 VGRDLKASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFT 266 D + +W + + + T S + +RL+ Sbjct: 495 GATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDG-EILASGSMDNTVRLWD 547 Score = 32.8 bits (73), Expect = 0.33, Method: Composition-based stats. Identities = 11/29 (37%), Positives = 15/29 (51%), Gaps = 3/29 (10%) Query: 158 KVVC---FNHDNTLLATGGTDGYVRVWKV 183 VC F+ D +LA+G D VR+W Sbjct: 520 DTVCSLRFSRDGEILASGSMDNTVRLWDA 548 >6QX9-4B nrPDB Length = 522 Score = 86.3 bits (212), Expect = 2e-17, Method: Composition-based stats. Identities = 47/285 (16%), Positives = 87/285 (30%), Gaps = 56/285 (19%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGP---------DGKLVT 212 F+ ++ +LAT G ++W VP + + H + + P D L + Sbjct: 239 FSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLAS 298 Query: 213 VGRDLKASVWQKDQLVTQLHWQENGPTFSSTPYRYQAC-RFGQVPDQPAGLRLFTVQIPH 271 D +W D + G T + RF RL+ ++ Sbjct: 299 CAADGSVKLWSLDS--DEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQE 356 Query: 272 KRLRQPPPCYLT----------------------AWDGSNFLPLRTKSCGHEVVSCLDVS 309 + L Q WD + + + ++ S Sbjct: 357 EILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFS 416 Query: 310 ESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEKGR------------ 357 +G + G+ + ++ +C+Y + AH +VT V F P G Sbjct: 417 PNGYHIATGSGDNTCKVWDLRQRRCVYTIP-AHQNLVTGVKFEPIHGNFLLTGAYDNTAK 475 Query: 358 --------GPELLGSHETALFSVAVDSRCQLHLLPS-RRSVPVWL 393 + L HE + + + S QL S R+ +W+ Sbjct: 476 IWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWM 520 Score = 69.0 bits (167), Expect = 4e-12, Method: Composition-based stats. Identities = 34/174 (19%), Positives = 59/174 (33%), Gaps = 27/174 (15%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDG-KLVTVGRDLK 218 + F+ D +L TGG D + RVW + + ++ + H EI + P+G + T D Sbjct: 371 IAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNT 430 Query: 219 ASVWQKDQ---LVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLR 275 VW Q + T Q P F ++ Sbjct: 431 CKVWDLRQRRCVYTIPAHQNLVTGVKFEPIH---GNFLLTGAYDNTAKI----------- 476 Query: 276 QPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIA 329 W + PL+T + V LD+S G + + + +++A Sbjct: 477 ---------WTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWMA 521 >6EOJ-D nrPDB Length = 470 Score = 83.2 bits (204), Expect = 2e-16, Method: Composition-based stats. Identities = 44/262 (16%), Positives = 86/262 (32%), Gaps = 58/262 (22%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFK-AHEGEIEDLALGP-DGKLVTVGRDLKA 219 ++HD+ + +G DG +++W+ P+ V E AH I D+A D K VT D Sbjct: 143 YSHDSDWMISGDADGMIKIWQ-PNFSMVKEIDAAHTESIRDMAFSSNDSKFVTCSDDNIL 201 Query: 220 SVW-----QKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRL 274 +W +++++++ HW G + Sbjct: 202 KIWNFSNGKQERVLSGHHWDVKSCD--------WHPEMGLIASASK-------------- 239 Query: 275 RQPPPCYLTAWDGSNFLPLRT-KSCGHEVVSCLDVSESGTFLGLGTVTGSVAI----YIA 329 + WD + + + H V+ G L + S + Y Sbjct: 240 ----DNLVKLWDPRSGNCISSILKFKHTVLKTRFQPTKGNLLMAISKDKSCRVFDIRYSM 295 Query: 330 FSLQCL-----YYVREAHGIVVTDVAFLPEKG--RGPELLG-----------SHETALFS 371 L C+ Y E H I + G + +LL +H+ + S Sbjct: 296 KELMCVRDETDYMTLEWHPINESMFTLACYDGSLKHFDLLQNLNEPILTIPYAHDKCITS 355 Query: 372 VAVDSRCQLHLLPSR-RSVPVW 392 ++ + + ++ R++ W Sbjct: 356 LSYNPVGHIFATAAKDRTIRFW 377 Score = 58.6 bits (140), Expect = 4e-09, Method: Composition-based stats. Identities = 28/220 (12%), Positives = 69/220 (31%), Gaps = 38/220 (17%) Query: 141 VENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIE 200 V+ + A T+ D + F+ +++ T D +++W + ++ H +++ Sbjct: 169 VKEIDAAHTESIRD-----MAFSSNDSKFVTCSDDNILKIWNFSNGKQERVLSGHHWDVK 223 Query: 201 DLALGPD-GKLVTVGRDLKASVWQK---DQLVTQLHWQENGPTFSSTPYRYQACRFGQVP 256 P+ G + + +D +W + + + L ++ P + Sbjct: 224 SCDWHPEMGLIASASKDNLVKLWDPRSGNCISSILKFKHTVLKTRFQPTKGNLLMAI--- 280 Query: 257 DQPAGLRLFTVQIPHKRL---RQPPPCYLTAW-------------DG---------SNFL 291 + R+F ++ K L R W DG + Sbjct: 281 SKDKSCRVFDIRYSMKELMCVRDETDYMTLEWHPINESMFTLACYDGSLKHFDLLQNLNE 340 Query: 292 PLRTKSCGHE-VVSCLDVSESGTFLGLGTVTGSVAIYIAF 330 P+ T H+ ++ L + G ++ + Sbjct: 341 PILTIPYAHDKCITSLSYNPVGHIFATAAKDRTIRFWTRA 380 Score = 55.5 bits (132), Expect = 4e-08, Method: Composition-based stats. Identities = 39/225 (17%), Positives = 73/225 (32%), Gaps = 34/225 (15%) Query: 140 RVENLQAVQTDFSSDPLQKVVC---FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHE 196 RV NL + T SS+ ++ V+ + + L G +W S +AH+ Sbjct: 76 RVINLPSKFTHLSSNKVKHVIPAIQWTPEGRRLVVATYSGEFSLWNASSFTFETLMQAHD 135 Query: 197 GEIEDLALGPDGK-LVTVGRDLKASVWQKDQLVTQL---HWQENGPTFSSTPYRYQACRF 252 + + D +++ D +WQ + + + E+ + + Sbjct: 136 SAVTTMKYSHDSDWMISGDADGMIKIWQPNFSMVKEIDAAHTESIRDMAFSSND----SK 191 Query: 253 GQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGH-EVVSCLDVSES 311 L++ W+ SN R S H +V SC E Sbjct: 192 FVTCSDDNILKI--------------------WNFSNGKQERVLSGHHWDVKSCDWHPEM 231 Query: 312 GTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEKG 356 G + + V ++ S C+ + + V+ F P KG Sbjct: 232 G-LIASASKDNLVKLWDPRSGNCISSILKFKHTVL-KTRFQPTKG 274 Score = 40.1 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 19/139 (13%), Positives = 44/139 (31%), Gaps = 15/139 (10%) Query: 165 DNTLLATGGTDGYVRVWKVP---SLEKVLEFKAHEGEIEDLALGPDGK-LVTVGRDLKAS 220 + ++ DG ++ + + + + AH+ I L+ P G T +D Sbjct: 316 NESMFTLACYDGSLKHFDLLQNLNEPILTIPYAHDKCITSLSYNPVGHIFATAAKDRTIR 375 Query: 221 VWQKDQLVTQLHWQEN------GPTFSSTPYR-----YQACRFGQVPDQPAGLRLFTVQI 269 W + + + + + + + FG P PA L + Sbjct: 376 FWTRARPIDPNAYDDPTYNNKKINGWFFGINNDINAVREKSEFGAAPPPPATLEPHALPN 435 Query: 270 PHKRLRQPPPCYLTAWDGS 288 + + + P + D + Sbjct: 436 MNGFINKKPRQEIPGIDSN 454 >3JAP-g nrPDB Length = 326 Score = 75.9 bits (185), Expect = 3e-14, Method: Composition-based stats. Identities = 29/158 (18%), Positives = 52/158 (32%), Gaps = 27/158 (17%) Query: 169 LATGGTDGYVRVWKV--PSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDLKASVWQKD 225 + G D VR W + S +F H I + PDG L + G+D + VW Sbjct: 174 FVSAGMDKIVRSWSLNEDSYRIEADFIGHNNYINVVQPSPDGSLAASAGKDGQIYVWNLK 233 Query: 226 QLVTQLHWQ--ENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQI-----------PHK 272 +++ + + +P R+ +G++++ ++ Sbjct: 234 HKSAFMNFDAKDEVFALAFSPSRFWLTAAT-----ASGIKIYDLENEVLIDELKPEFAGY 288 Query: 273 RLRQPPPCYLTAW--DGSNFLPLRTKSCGHEVVSCLDV 308 Q P AW DG T + V+ V Sbjct: 289 TKAQDPHAVSLAWSADGQTLFAGYTDN----VIRVWQV 322 Score = 57.4 bits (137), Expect = 1e-08, Method: Composition-based stats. Identities = 36/208 (17%), Positives = 68/208 (32%), Gaps = 22/208 (10%) Query: 153 SDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPD-GKLV 211 S +Q VV + D + D +R+W + + F H G++ +A+ + K++ Sbjct: 66 SHIVQDVVV-SADGNYAVSASWDKTLRLWNLATGNSEARFVGHTGDVLSVAIDANSSKII 124 Query: 212 TVGRDLKASVWQK--DQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQI 269 + RD VW D L + P + + G F Sbjct: 125 SASRDKTIRVWNTVGDCAYVLLGHTDWVTKVRVAPKN------LEDGEVDDGRITFVSAG 178 Query: 270 PHKRLRQPPPCYLTAWDGS-NFLPLRTKSCGH-EVVSCLDVSESGTFLGLGTVTGSVAIY 327 K +R +W + + + GH ++ + S G+ G IY Sbjct: 179 MDKIVR--------SWSLNEDSYRIEADFIGHNNYINVVQPSPDGSLAASAGKDG--QIY 228 Query: 328 IAFSLQCLYYVREAHGIVVTDVAFLPEK 355 + ++ V +AF P + Sbjct: 229 VWNLKHKSAFMNFDAKDEVFALAFSPSR 256 Score = 39.7 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 15/63 (23%), Positives = 27/63 (42%), Gaps = 6/63 (9%) Query: 168 LLATGGTDGYVRVWKVPSLEK-----VLEFKAHEGEIEDLALGPDGKL-VTVGRDLKASV 221 LL +G D + W++ E+ V +K H ++D+ + DG V+ D + Sbjct: 33 LLVSGSRDKTLISWRLTENEQQFGVPVRSYKGHSHIVQDVVVSADGNYAVSASWDKTLRL 92 Query: 222 WQK 224 W Sbjct: 93 WNL 95 >6QX9-5O nrPDB Length = 357 Score = 74.4 bits (181), Expect = 1e-13, Method: Composition-based stats. Identities = 37/231 (16%), Positives = 69/231 (29%), Gaps = 45/231 (19%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK--LVTVGRDLKA 219 +N D ++L + TD V VW + E+V K H + G + T D Sbjct: 117 YNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTV 176 Query: 220 SVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPP 279 +W + +Q + T ++++ + R + Sbjct: 177 KLWDIRKKAAIQTFQNTYQVLAVTFN--DTSDQIISGGIDNDIKVWDL-----RQNKLTY 229 Query: 280 CYLTAWDGSNFLPLRTK------SCGHEVVSCLDV------------------------- 308 D L L ++ + V DV Sbjct: 230 TMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLL 289 Query: 309 ----SESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEK 355 S G+ + G+ V ++ S + LY + H + +VAF P++ Sbjct: 290 RCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLP-GHAGSINEVAFHPDE 339 Score = 53.6 bits (127), Expect = 2e-07, Method: Composition-based stats. Identities = 15/61 (24%), Positives = 29/61 (47%), Gaps = 1/61 (1%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK-LVTVGRDLKAS 220 ++ D + +A G D +V VW S + + H G I ++A PD +++ D + Sbjct: 293 WSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLY 352 Query: 221 V 221 + Sbjct: 353 M 353 Score = 43.6 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 33/226 (14%), Positives = 58/226 (25%), Gaps = 50/226 (22%) Query: 192 FKAHEGEIEDLALGPDGK-LVTVGRDLKASVWQKDQLVTQLHWQENGPTFSSTPYRYQAC 250 HEGE+ P+G L + G D +W Y C Sbjct: 62 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLW----------------------NVYGDC 99 Query: 251 R--FGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHE--VVSCL 306 A + L + WD ++ GH V SC Sbjct: 100 DNYATLKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLK-GHTSFVNSCY 158 Query: 307 DVSESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEKGRGPE------ 360 + G+ G+V ++ + + + V V F + Sbjct: 159 PARRGPQLVCTGSDDGTVKLWDIRKKAAIQTFQNTYQ--VLAVTFNDTSDQIISGGIDND 216 Query: 361 -------------LLGSHETALFSVAVDSRCQLHLLPS-RRSVPVW 392 + H ++ +++ S L + +V VW Sbjct: 217 IKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVW 262 >5MWJ-A nrPDB Length = 337 Score = 73.6 bits (179), Expect = 1e-13, Method: Composition-based stats. Identities = 35/200 (17%), Positives = 63/200 (31%), Gaps = 29/200 (14%) Query: 152 SSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDG-KL 210 SS P + + D+ + + +DG + VW + + V +F+ H + + DG KL Sbjct: 139 SSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKL 198 Query: 211 VTVGRDLKASVWQK--DQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQ 268 T G D W + + Q + + P V + + + + V Sbjct: 199 WTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLA----VGMESSNVEVLHVN 254 Query: 269 IPHKRLRQPPPC---------------------YLTAWDGSNFLPLRTKSCGHEVVSCLD 307 P K L AW + V+SC D Sbjct: 255 KPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSC-D 313 Query: 308 VSESGTFLGLGTVTGSVAIY 327 +S ++ G+ +Y Sbjct: 314 ISVDDKYIVTGSGDKKATVY 333 Score = 44.3 bits (103), Expect = 9e-05, Method: Composition-based stats. Identities = 21/140 (15%), Positives = 44/140 (31%), Gaps = 25/140 (17%) Query: 152 SSDPLQKVVCFNHDNTL-----------LATGGTDGYVRVWKV--PSLEKVLEFKAHEGE 198 + P+ ++ C N DN + L GG + +W + P+ E + Sbjct: 84 NKSPVSQLDCLNRDNYIRSCKLLPDGCTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPA 143 Query: 199 IEDLALGPDGKLV-TVGRDLKASVWQKD-----QLVTQLHWQENGPTFSSTPYRYQACRF 252 LA+ PD K+ + D +VW + + S+ + Sbjct: 144 CYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLW---- 199 Query: 253 GQVPDQPAGLRLFTVQIPHK 272 +R + ++ + Sbjct: 200 --TGGLDNTVRSWDLREGRQ 217 Score = 35.9 bits (81), Expect = 0.036, Method: Composition-based stats. Identities = 13/63 (20%), Positives = 25/63 (39%), Gaps = 2/63 (3%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDLKAS 220 F + + G D + W+ P + + K + + D K + T D KA+ Sbjct: 273 FAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSC-DISVDDKYIVTGSGDKKAT 331 Query: 221 VWQ 223 V++ Sbjct: 332 VYE 334 >5FL8-q nrPDB Length = 515 Score = 72.8 bits (177), Expect = 2e-13, Method: Composition-based stats. Identities = 42/252 (16%), Positives = 79/252 (31%), Gaps = 51/252 (20%) Query: 165 DNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQ- 223 LA+ DG +++W S H + + G G L + D VW Sbjct: 247 SKPRLASSSKDGTIKIWDTVSRVCQYTMSGHTNSVSCVKWGGQGLLYSGSHDRTVRVWDI 306 Query: 224 --KDQLVTQL----HWQENGPTFS-STPYRYQACRFGQVPDQPAGLR------LFTVQIP 270 + + + L HW S ST Y + F +P+ L + Sbjct: 307 NSQGRCINILKSHAHW---VNHLSLSTDYALRIGAFDHTGKKPSTPEEAQKKALENYEKI 363 Query: 271 HKRLRQPPPCYLTAWDGSNF---------LPLRTKSCGHEVVSCLDVSESGTFLGLGTVT 321 K+ +TA D P+ + ++V+ + S G ++ + Sbjct: 364 CKKNGNSEEMMVTASDDYTMFLWNPLKSTKPIARMTGHQKLVNHVAFSPDGRYIVSASFD 423 Query: 322 GSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEKGRGPELLGSHETALFSVAVDSRCQLH 381 S+ ++ G+ H +++ VA S C+L Sbjct: 424 NSIKLWDG------------------------RDGKFISTFRGHVASVYQVAWSSDCRLL 459 Query: 382 LLPSRR-SVPVW 392 + S+ ++ VW Sbjct: 460 VSCSKDTTLKVW 471 Score = 65.5 bits (158), Expect = 4e-11, Method: Composition-based stats. Identities = 30/180 (16%), Positives = 61/180 (33%), Gaps = 20/180 (11%) Query: 164 HDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDLKASVW 222 H ++ + TG D R+W + + K H + ++ PDG+++ T D +W Sbjct: 154 HTSSRMVTGAGDNTARIWDCDTQTPMHTLKGHYNWVLCVSWSPDGEVIATGSMDNTIRLW 213 Query: 223 QKDQLVTQLHWQENGPTFS--STPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPC 280 + + S T ++ + +P Sbjct: 214 DPK---SGQCLGDALRGHSKWITSLSWEPIHLVKPGSKPR------------LASSSKDG 258 Query: 281 YLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSL-QCLYYVR 339 + WD + + T S VSC+ G L G+ +V ++ S +C+ ++ Sbjct: 259 TIKIWDTVSRVCQYTMSGHTNSVSCVKWGGQG-LLYSGSHDRTVRVWDINSQGRCINILK 317 Score = 57.8 bits (138), Expect = 7e-09, Method: Composition-based stats. Identities = 14/65 (21%), Positives = 28/65 (43%), Gaps = 1/65 (1%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK-LVTVGRDLK 218 V F+ D + + D +++W + + F+ H + +A D + LV+ +D Sbjct: 408 VAFSPDGRYIVSASFDNSIKLWDGRDGKFISTFRGHVASVYQVAWSSDCRLLVSCSKDTT 467 Query: 219 ASVWQ 223 VW Sbjct: 468 LKVWD 472 Score = 55.5 bits (132), Expect = 4e-08, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 32/64 (50%), Gaps = 1/64 (1%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK-LVTVGRDLK 218 V ++ D LL + D ++VW V + + ++ H+ E+ + DGK + + G+D Sbjct: 450 VAWSSDCRLLVSCSKDTTLKVWDVRTRKLSVDLPGHKDEVYTVDWSVDGKRVCSGGKDKM 509 Query: 219 ASVW 222 +W Sbjct: 510 VRLW 513 Score = 50.9 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 26/134 (19%), Positives = 46/134 (34%), Gaps = 6/134 (4%) Query: 262 LRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVT 321 F + + WD P+ T + V C+ S G + G++ Sbjct: 148 CSAFAPHTSSRMVTGAGDNTARIWDCDTQTPMHTLKGHYNWVLCVSWSPDGEVIATGSMD 207 Query: 322 GSVAIYIAFSLQCLYYVREAHGIVVTDVAFLP----EKGRGPELLGSHETALFSV--AVD 375 ++ ++ S QCL H +T +++ P + G P L S + + V Sbjct: 208 NTIRLWDPKSGQCLGDALRGHSKWITSLSWEPIHLVKPGSKPRLASSSKDGTIKIWDTVS 267 Query: 376 SRCQLHLLPSRRSV 389 CQ + SV Sbjct: 268 RVCQYTMSGHTNSV 281 Score = 50.1 bits (118), Expect = 2e-06, Method: Composition-based stats. Identities = 34/195 (17%), Positives = 58/195 (29%), Gaps = 33/195 (16%) Query: 194 AHEGEIEDLALGP--DGKLVTVGRDLKASVWQKDQLVTQLHWQENGPTFSSTPYRYQAC- 250 H I A P ++VT D A +W D + + Y + C Sbjct: 141 GHGSTILCSAFAPHTSSRMVTGAGDNTARIWDCDTQTPMHTLKGH--------YNWVLCV 192 Query: 251 ------RFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVS 304 +RL+ P D S E + Sbjct: 193 SWSPDGEVIATGSMDNTIRLWD-----------PKSGQCLGDALRGHSKWITSLSWEPIH 241 Query: 305 CLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEKGRGPELLGS 364 + S L + G++ I+ S C Y + H V+ V + G+G GS Sbjct: 242 LVK-PGSKPRLASSSKDGTIKIWDTVSRVCQYTM-SGHTNSVSCVKW---GGQGLLYSGS 296 Query: 365 HETALFSVAVDSRCQ 379 H+ + ++S+ + Sbjct: 297 HDRTVRVWDINSQGR 311 >6Q8F-A nrPDB Length = 514 Score = 72.1 bits (175), Expect = 5e-13, Method: Composition-based stats. Identities = 19/64 (29%), Positives = 33/64 (51%), Gaps = 2/64 (3%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEF-KAHEGEIEDLALGPDGKLV-TVGRDL 217 +CF+ D +LATG DG ++VWK+ S + + F +AH + L+ D + + D Sbjct: 271 MCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQ 330 Query: 218 KASV 221 + Sbjct: 331 TIRI 334 Score = 55.1 bits (131), Expect = 5e-08, Method: Composition-based stats. Identities = 33/212 (15%), Positives = 67/212 (31%), Gaps = 44/212 (20%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAH--------EGEIEDLALGPDGK-LVT 212 F+ D L TG DG++ VW + + + K + + + D + L T Sbjct: 223 FSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLAT 282 Query: 213 VGRDLKASVWQKD-----QLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTV 267 +D K VW+ + + H + S + Q +R+ + Sbjct: 283 GAQDGKIKVWKIQSGQCLRRFERAH-SKGVTCLSFSKDSSQ----ILSASFDQTIRIHGL 337 Query: 268 QIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIY 327 + + L+ V+ ++ G ++ + G+V I+ Sbjct: 338 K--------------------SGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIW 377 Query: 328 IAFSLQCLYYVRE-----AHGIVVTDVAFLPE 354 + +C + I V V LP+ Sbjct: 378 NMKTTECSNTFKSLGSTAGTDITVNSVILLPK 409 Score = 37.4 bits (85), Expect = 0.011, Method: Composition-based stats. Identities = 17/89 (19%), Positives = 33/89 (37%), Gaps = 6/89 (6%) Query: 141 VENLQA-VQTDFSSDPLQ--KVVC--FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAH 195 + N+Q + FSS + VC + + G D + + + + H Sbjct: 425 IMNMQGQIVRSFSSGKREGGDFVCCALSPRGEWIYCVGEDFVLYCFSTVTGKLERTLTVH 484 Query: 196 EGEIEDLALGPDGKLV-TVGRDLKASVWQ 223 E ++ +A P L+ T D +W+ Sbjct: 485 EKDVIGIAHHPHQNLIATYSEDGLLKLWK 513 Score = 37.4 bits (85), Expect = 0.012, Method: Composition-based stats. Identities = 20/90 (22%), Positives = 36/90 (40%), Gaps = 11/90 (12%) Query: 301 EVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEKGRGPE 360 + V C+ S L G G + ++ S QCL AH VT ++F + + Sbjct: 266 DAVLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQ--- 322 Query: 361 LLGSHETALFSVAVDSRCQLHLLPSRRSVP 390 + S + D ++H L S +++ Sbjct: 323 --------ILSASFDQTIRIHGLKSGKTLK 344 >5K1B-B nrPDB Length = 677 Score = 70.5 bits (171), Expect = 1e-12, Method: Composition-based stats. Identities = 36/195 (18%), Positives = 68/195 (34%), Gaps = 16/195 (8%) Query: 153 SDPLQKVV-CFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV 211 +D + +V C N L + +D V+VW + + H+ ++ LA D +LV Sbjct: 75 TDWVNDIVLCCN--GKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELV 132 Query: 212 -TVGRDLKASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIP 270 + G D + +W + L T S + ++ + L Q+ Sbjct: 133 ASAGLDRQIFLWDVNTLTALTASNNTVTTSSLS------------GNKDSIYSLAMNQLG 180 Query: 271 HKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAF 330 + L WD L + V L ++ GT G+ G++ ++ Sbjct: 181 TIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWSLG 240 Query: 331 SLQCLYYVREAHGIV 345 +C+ R V Sbjct: 241 QQRCIATYRVHDEGV 255 Score = 43.9 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 27/204 (13%), Positives = 59/204 (28%), Gaps = 47/204 (23%) Query: 197 GEIEDLALGPD-GKLVTVGRDLKASVWQKDQ------LVTQLHWQENGPTFSSTPYRYQA 249 + L L P +L T GRD +W +Q + + H + Sbjct: 31 NGVNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDIVLCCNGKTL 90 Query: 250 CRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVS 309 +++ W+ + T + V L + Sbjct: 91 ISA----SSDTTVKV--------------------WNAHKGFCMSTLRTHKDYVKALAYA 126 Query: 310 ESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEKGRGPELLGSHETAL 369 + + + + ++ +L L A VT + L ++ ++ Sbjct: 127 KDKELVASAGLDRQIFLWDVNTLTALT----ASNNTVTTSS-----------LSGNKDSI 171 Query: 370 FSVAVDSRCQLHLLPSRRSV-PVW 392 +S+A++ + + S V VW Sbjct: 172 YSLAMNQLGTIIVSGSTEKVLRVW 195 Score = 42.8 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 29/70 (41%), Gaps = 1/70 (1%) Query: 158 KVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPD-GKLVTVGRD 216 K + N D T +G +DG +R+W + + ++ H+ + L + + + GRD Sbjct: 214 KALLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFTHVYSGGRD 273 Query: 217 LKASVWQKDQ 226 K Sbjct: 274 RKIYCTDLRN 283 >6E29-D nrPDB Length = 345 Score = 68.6 bits (166), Expect = 4e-12, Method: Composition-based stats. Identities = 38/189 (20%), Positives = 72/189 (38%), Gaps = 4/189 (2%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK-LVTVGRDLKAS 220 FN LA+G DG V +W + ++ + + H I L+ G+ L++ + K Sbjct: 33 FNRKGDFLASGRVDGTVVIWDLETMGVARKLRGHSKNITSLSWSRCGRYLLSACQGWKVI 92 Query: 221 VWQK--DQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPP 278 +W + ++ ++ P+ + DQP + + L P Sbjct: 93 LWDLQDGKRYREVRFRAPVYGAELHPWNHHQFAAALFEDQPMLVDITEPVEVRYVLPSVP 152 Query: 279 PCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYV 338 T D + + K + + + + SG L GT G + I A + + +Y Sbjct: 153 KRTSTETDPA-LREKQAKEDAKHMTTAIVYTASGDHLLAGTTKGRLNIIDARTREIIYSE 211 Query: 339 REAHGIVVT 347 + A GI+ T Sbjct: 212 KIASGIITT 220 Score = 30.5 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 15/57 (26%), Positives = 27/57 (47%), Gaps = 3/57 (5%) Query: 295 TKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAF 351 T GH +C+ + G FL G V G+V I+ ++ +R H +T +++ Sbjct: 22 TIRSGHS--TCVRFNRKGDFLASGRVDGTVVIWDLETMGVARKLR-GHSKNITSLSW 75 >5WLC-LO nrPDB Length = 923 Score = 67.1 bits (162), Expect = 1e-11, Method: Composition-based stats. Identities = 25/172 (14%), Positives = 48/172 (27%), Gaps = 20/172 (11%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDLKAS 220 ++ D + + T DG ++VW + S + F+ H + + G+++ + D Sbjct: 353 YSPDGSRVVTASEDGKIKVWDITSGFCLATFEEHTSSVTAVQFAKRGQVMFSSSLDGTVR 412 Query: 221 VWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPC 280 W +R F Sbjct: 413 AWDL---------------IRYRNFR----TFTGTERIQFNCLAVDPSGEVVCAGSLDNF 453 Query: 281 YLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSL 332 + W L S VSCL S+ + L + ++ I+ F Sbjct: 454 DIHVWSVQTGQLLDALSGHEGPVSCLSFSQENSVLASASWDKTIRIWSIFGR 505 Score = 55.1 bits (131), Expect = 5e-08, Method: Composition-based stats. Identities = 34/261 (13%), Positives = 84/261 (32%), Gaps = 50/261 (19%) Query: 158 KVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDL 217 K V F+ LLA G T G R++ +P + + + + +++ G+ + G Sbjct: 264 KCVTFHPATRLLAVGFTSGEFRLYDLPDFTLIQQLSMGQNPVNTVSVNQTGEWLAFGSSK 323 Query: 218 KASV----WQKDQ-LVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHK 272 + WQ + ++ Q ++ + + +P + +++ Sbjct: 324 LGQLLVYEWQSESYILKQQGHFDSTNSLAYSPDG----SRVVTASEDGKIKV-------- 371 Query: 273 RLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSL 332 WD ++ L T V+ + ++ G + ++ G+V + Sbjct: 372 ------------WDITSGFCLATFEEHTSSVTAVQFAKRGQVMFSSSLDGTVRAWDLIRY 419 Query: 333 QCLYYVREAHGIVVTDVAFLP--------------------EKGRGPELLGSHETALFSV 372 + I +A P + G+ + L HE + + Sbjct: 420 RNFRTFTGTERIQFNCLAVDPSGEVVCAGSLDNFDIHVWSVQTGQLLDALSGHEGPVSCL 479 Query: 373 AVDSRCQLHLLPS-RRSVPVW 392 + + S +++ +W Sbjct: 480 SFSQENSVLASASWDKTIRIW 500 Score = 38.6 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 15/53 (28%), Positives = 29/53 (54%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVG 214 F+ +N++LA+ D +R+W + + +E ++ L++ PDGK V V Sbjct: 481 FSQENSVLASASWDKTIRIWSIFGRSQQVEPIEVYSDVLALSMRPDGKEVAVS 533 Score = 36.2 bits (82), Expect = 0.029, Method: Composition-based stats. Identities = 24/123 (19%), Positives = 40/123 (32%), Gaps = 9/123 (7%) Query: 163 NHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVW 222 N TLL + DG + + + F E + PDG+L + +W Sbjct: 64 NKQGTLLISIDEDGRAILVNFKARNVLHHFNFKEK-CSAVKFSPDGRLFALASGRFLQIW 122 Query: 223 Q-----KDQLVT--QLHWQENGPTFSSTPYRY-QACRFGQVPDQPAGLRLFTVQIPHKRL 274 + KD+ H G T + Q RF + ++++V K L Sbjct: 123 KTPDVNKDRQFAPFVRHRVHAGHFQDITSLTWSQDSRFILTTSKDLSAKIWSVDSEEKNL 182 Query: 275 RQP 277 Sbjct: 183 AAT 185 >5I2T-A nrPDB Length = 742 Score = 67.1 bits (162), Expect = 1e-11, Method: Composition-based stats. Identities = 25/172 (14%), Positives = 48/172 (27%), Gaps = 20/172 (11%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDLKAS 220 ++ D + + T DG ++VW + S + F+ H + + G+++ + D Sbjct: 378 YSPDGSRVVTASEDGKIKVWDITSGFCLATFEEHTSSVTAVQFAKRGQVMFSSSLDGTVR 437 Query: 221 VWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPC 280 W +R F Sbjct: 438 AWDL---------------IRYRNFR----TFTGTERIQFNCLAVDPSGEVVCAGSLDNF 478 Query: 281 YLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSL 332 + W L S VSCL S+ + L + ++ I+ F Sbjct: 479 DIHVWSVQTGQLLDALSGHEGPVSCLSFSQENSVLASASWDKTIRIWSIFGR 530 Score = 55.1 bits (131), Expect = 5e-08, Method: Composition-based stats. Identities = 34/261 (13%), Positives = 84/261 (32%), Gaps = 50/261 (19%) Query: 158 KVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDL 217 K V F+ LLA G T G R++ +P + + + + +++ G+ + G Sbjct: 289 KCVTFHPATRLLAVGFTSGEFRLYDLPDFTLIQQLSMGQNPVNTVSVNQTGEWLAFGSSK 348 Query: 218 KASV----WQKDQ-LVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHK 272 + WQ + ++ Q ++ + + +P + +++ Sbjct: 349 LGQLLVYEWQSESYILKQQGHFDSTNSLAYSPDG----SRVVTASEDGKIKV-------- 396 Query: 273 RLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSL 332 WD ++ L T V+ + ++ G + ++ G+V + Sbjct: 397 ------------WDITSGFCLATFEEHTSSVTAVQFAKRGQVMFSSSLDGTVRAWDLIRY 444 Query: 333 QCLYYVREAHGIVVTDVAFLP--------------------EKGRGPELLGSHETALFSV 372 + I +A P + G+ + L HE + + Sbjct: 445 RNFRTFTGTERIQFNCLAVDPSGEVVCAGSLDNFDIHVWSVQTGQLLDALSGHEGPVSCL 504 Query: 373 AVDSRCQLHLLPS-RRSVPVW 392 + + S +++ +W Sbjct: 505 SFSQENSVLASASWDKTIRIW 525 Score = 38.6 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 15/53 (28%), Positives = 29/53 (54%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVG 214 F+ +N++LA+ D +R+W + + +E ++ L++ PDGK V V Sbjct: 506 FSQENSVLASASWDKTIRIWSIFGRSQQVEPIEVYSDVLALSMRPDGKEVAVS 558 Score = 36.2 bits (82), Expect = 0.029, Method: Composition-based stats. Identities = 24/123 (19%), Positives = 40/123 (32%), Gaps = 9/123 (7%) Query: 163 NHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVW 222 N TLL + DG + + + F E + PDG+L + +W Sbjct: 89 NKQGTLLISIDEDGRAILVNFKARNVLHHFNFKEK-CSAVKFSPDGRLFALASGRFLQIW 147 Query: 223 Q-----KDQLVT--QLHWQENGPTFSSTPYRY-QACRFGQVPDQPAGLRLFTVQIPHKRL 274 + KD+ H G T + Q RF + ++++V K L Sbjct: 148 KTPDVNKDRQFAPFVRHRVHAGHFQDITSLTWSQDSRFILTTSKDLSAKIWSVDSEEKNL 207 Query: 275 RQP 277 Sbjct: 208 AAT 210 >5Z56-q nrPDB Length = 504 Score = 66.7 bits (161), Expect = 2e-11, Method: Composition-based stats. Identities = 43/220 (19%), Positives = 80/220 (36%), Gaps = 34/220 (15%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKA 219 V F+ L+ + D +R+W VP+ V +AHE + L+L G + D + Sbjct: 270 VVFHPSQDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQ- 328 Query: 220 SVW-----QKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTV------- 267 W Q +++T++ + +G + + + FG + ++++ + Sbjct: 329 -YWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFG-TGTMDSQIKIWDLKERTNVA 386 Query: 268 ---------------QIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEV-VSCLDVSES 311 + + + WD +T + V L +S Sbjct: 387 NFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQS 446 Query: 312 GTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAF 351 GT+L LG V IYI + + E H + T VAF Sbjct: 447 GTYLALGGTD--VQIYICKQWTEILHFTE-HSGLTTGVAF 483 Score = 65.5 bits (158), Expect = 4e-11, Method: Composition-based stats. Identities = 43/232 (18%), Positives = 75/232 (32%), Gaps = 26/232 (11%) Query: 165 DNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDLKASVWQ 223 D + TGG D V V+ S + + K H ++ + P LV + D +W Sbjct: 233 DTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIWS 292 Query: 224 ------------KDQLVTQLHWQENGPT-FSSTPYRYQACRFGQVP-------DQPAGLR 263 + VT L G SS+ +Y A Q D+ +G Sbjct: 293 VPNASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCS 352 Query: 264 LFTVQIPHKRL---RQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTV 320 L Q L + WD + ++ + SE+G +L Sbjct: 353 LTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAAD 412 Query: 321 TGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEKGRGPELLGSHETALFSV 372 SV ++ L+ ++ + V + F + G LG + ++ Sbjct: 413 DSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFD-QSGTYL-ALGGTDVQIYIC 462 Score = 30.1 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 18/96 (18%), Positives = 36/96 (37%), Gaps = 21/96 (21%) Query: 309 SESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEK------------- 355 S++ L G +V ++ S Q L ++ H VT V F P + Sbjct: 232 SDTNKIL-TGGADKNVVVFDKSSEQILATLK-GHTKKVTSVVFHPSQDLVFSASPDATIR 289 Query: 356 ------GRGPELLGSHETALFSVAVDSRCQLHLLPS 385 +++ +HE+A+ +++ + L S Sbjct: 290 IWSVPNASCVQVVRAHESAVTGLSLHATGDYLLSSS 325 >4LG8-A nrPDB Length = 354 Score = 66.7 bits (161), Expect = 2e-11, Method: Composition-based stats. Identities = 43/220 (19%), Positives = 80/220 (36%), Gaps = 34/220 (15%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKA 219 V F+ L+ + D +R+W VP+ V +AHE + L+L G + D + Sbjct: 120 VVFHPSQDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQ- 178 Query: 220 SVW-----QKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTV------- 267 W Q +++T++ + +G + + + FG + ++++ + Sbjct: 179 -YWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFG-TGTMDSQIKIWDLKERTNVA 236 Query: 268 ---------------QIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEV-VSCLDVSES 311 + + + WD +T + V L +S Sbjct: 237 NFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQS 296 Query: 312 GTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAF 351 GT+L LG V IYI + + E H + T VAF Sbjct: 297 GTYLALGGTD--VQIYICKQWTEILHFTE-HSGLTTGVAF 333 Score = 65.5 bits (158), Expect = 4e-11, Method: Composition-based stats. Identities = 43/232 (18%), Positives = 75/232 (32%), Gaps = 26/232 (11%) Query: 165 DNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDLKASVWQ 223 D + TGG D V V+ S + + K H ++ + P LV + D +W Sbjct: 83 DTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIWS 142 Query: 224 ------------KDQLVTQLHWQENGPT-FSSTPYRYQACRFGQVP-------DQPAGLR 263 + VT L G SS+ +Y A Q D+ +G Sbjct: 143 VPNASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCS 202 Query: 264 LFTVQIPHKRL---RQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTV 320 L Q L + WD + ++ + SE+G +L Sbjct: 203 LTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAAD 262 Query: 321 TGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEKGRGPELLGSHETALFSV 372 SV ++ L+ ++ + V + F + G LG + ++ Sbjct: 263 DSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFD-QSGTYL-ALGGTDVQIYIC 312 Score = 30.1 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 18/96 (18%), Positives = 36/96 (37%), Gaps = 21/96 (21%) Query: 309 SESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEK------------- 355 S++ L G +V ++ S Q L ++ H VT V F P + Sbjct: 82 SDTNKIL-TGGADKNVVVFDKSSEQILATLK-GHTKKVTSVVFHPSQDLVFSASPDATIR 139 Query: 356 ------GRGPELLGSHETALFSVAVDSRCQLHLLPS 385 +++ +HE+A+ +++ + L S Sbjct: 140 IWSVPNASCVQVVRAHESAVTGLSLHATGDYLLSSS 175 >5NZU-C nrPDB Length = 905 Score = 65.9 bits (159), Expect = 3e-11, Method: Composition-based stats. Identities = 43/229 (18%), Positives = 79/229 (34%), Gaps = 28/229 (12%) Query: 168 LLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDLKASVWQKDQ 226 + TG D +RV+ +LE+V F+AH I +A+ P + T D+ +W D+ Sbjct: 71 WVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDK 130 Query: 227 LVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRL-FTVQIPHKRLRQPPPCYLTAW 285 +C +++ + ++ + W Sbjct: 131 K--------------------WSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVW 170 Query: 286 DGSNFLPLRTKSCGHEVVSCLDVSESGT--FLGLGTVTGSVAIYIAFSLQCLYYVREAHG 343 + P T + V+C+D G +L G V I+ + C+ + E H Sbjct: 171 QLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTL-EGHA 229 Query: 344 IVVTDVAFLPEKGRGPELLGSHETALFSVAVDSRCQLHLLPSRRSVPVW 392 V+ +F PE P ++ E + S +L + VW Sbjct: 230 QNVSCASFHPEL---PIIITGSEDGTVRIWHSSTYRLESTLNYGMERVW 275 Score = 61.3 bits (147), Expect = 8e-10, Method: Composition-based stats. Identities = 27/172 (15%), Positives = 53/172 (30%), Gaps = 24/172 (13%) Query: 158 KVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK---LVTVG 214 ++V DN A+ D ++VW++ S + HE + + G L++ Sbjct: 147 QIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGA 206 Query: 215 RDLKASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRL 274 D +W + + S + + + +R+ Sbjct: 207 DDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPEL-PIIITGSEDGTVRI---------- 255 Query: 275 RQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAI 326 W S + T + G E V C+ + LG GS+ + Sbjct: 256 ----------WHSSTYRLESTLNYGMERVWCVASLRGSNNVALGYDEGSIIV 297 Score = 39.3 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 17/86 (19%), Positives = 31/86 (36%), Gaps = 2/86 (2%) Query: 157 QKVVC--FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVG 214 Q V C F+ + ++ TG DG VR+W + + +A V +G Sbjct: 230 QNVSCASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCVASLRGSNNVALG 289 Query: 215 RDLKASVWQKDQLVTQLHWQENGPTF 240 D + + + + + NG Sbjct: 290 YDEGSIIVKLGREEPAMSMDANGKII 315 >4U1E-I nrPDB Length = 347 Score = 65.9 bits (159), Expect = 3e-11, Method: Composition-based stats. Identities = 38/215 (17%), Positives = 72/215 (33%), Gaps = 12/215 (5%) Query: 144 LQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLA 203 ++A++ PL +V +N + LL + D VW + E++ H G I + Sbjct: 1 MKAIKLTGHERPLTQVK-YNKEGDLLFSCSKDSSASVWYSLNGERLGTLDGHTGTIWSID 59 Query: 204 LGPDGKLV-TVGRDLKASVWQKDQLVTQLHWQENGP--TFSSTP-YRYQACRFGQVPDQP 259 + K T D +W W+ P +P Y V P Sbjct: 60 VDCFTKYCVTGSADYSIKLWDVSNGQCVATWKSPVPVKRVEFSPCGNYFLAILDNVMKNP 119 Query: 260 AGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGT 319 + ++ ++ R LT + T G + + S G ++ G Sbjct: 120 GSINIYEIE------RDSATHELTKVSEEPIHKIIT-HEGLDAATVAGWSTKGKYIIAGH 172 Query: 320 VTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPE 354 G ++ Y + + H ++D+ F P+ Sbjct: 173 KDGKISKYDVSNNYEYVDSIDLHEKSISDMQFSPD 207 Score = 31.2 bits (69), Expect = 0.80, Method: Composition-based stats. Identities = 17/95 (17%), Positives = 32/95 (33%), Gaps = 14/95 (14%) Query: 141 VENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGY-------------VRVWKVPSLE 187 V LQ ++ + PL V ++ GG + R + E Sbjct: 225 VSTLQVLKKYETDCPLNTAVITPLKEFIILGGGQEAKDVTTTSANEGKFEARFYHKIFEE 284 Query: 188 KVLEFKAHEGEIEDLALGPDG-KLVTVGRDLKASV 221 ++ + H G + +A+ P G + G D + Sbjct: 285 EIGRVQGHFGPLNTVAISPQGTSYASGGEDGFIRL 319 >5UZ7-B nrPDB Length = 351 Score = 64.4 bits (155), Expect = 8e-11, Method: Composition-based stats. Identities = 28/167 (16%), Positives = 49/167 (29%), Gaps = 24/167 (14%) Query: 164 HDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK-LVTVGRDLKASVW 222 D L +G D ++W V F HE +I + P+G T D ++ Sbjct: 205 PDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLF 264 Query: 223 Q--KDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPC 280 DQ + +S + ++ R + Sbjct: 265 DLRADQELMTYSHDNIICGITSVSFS-KSGRLLLAGYDDFNCNV---------------- 307 Query: 281 YLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIY 327 WD + VSCL V++ G + G+ + I+ Sbjct: 308 ----WDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 350 Score = 49.3 bits (116), Expect = 3e-06, Method: Composition-based stats. Identities = 39/238 (16%), Positives = 74/238 (31%), Gaps = 35/238 (14%) Query: 165 DNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGR-DLKASVWQ 223 D+ LL + DG + +W + KV + A P G V G D S++ Sbjct: 77 DSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIY- 135 Query: 224 KDQLVTQLHWQENGPTFSSTPYRYQACRF-----GQVPDQPAGLRLFTVQI--------- 269 L T+ + CRF L+ ++ Sbjct: 136 --NLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTG 193 Query: 270 -----------PHKRLRQPPPCYLTA--WDGSNFLPLRTKSCGHEVVSCLDVSESGTFLG 316 P RL C +A WD + +T + ++ + +G Sbjct: 194 HTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFA 253 Query: 317 LGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEKGRGPELLGSHETALFSVAV 374 G+ + ++ + Q L + +H ++ + + G LL ++ F+ V Sbjct: 254 TGSDDATCRLFDLRADQEL--MTYSHDNIICGITSVSFSKSGRLLLAGYDD--FNCNV 307 Score = 42.4 bits (98), Expect = 3e-04, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 23/65 (35%), Gaps = 1/65 (1%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDG-KLVTVGRDLK 218 V F+ LL G D VW ++ H+ + L + DG + T D Sbjct: 287 VSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSF 346 Query: 219 ASVWQ 223 +W Sbjct: 347 LKIWN 351 Score = 41.6 bits (96), Expect = 7e-04, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 33/69 (47%), Gaps = 5/69 (7%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEG---EIEDLALGPDGKLVTVG-R 215 +CF + ATG D R++ + + ++++ + +H+ I ++ G+L+ G Sbjct: 243 ICFFPNGNAFATGSDDATCRLFDLRADQELMTY-SHDNIICGITSVSFSKSGRLLLAGYD 301 Query: 216 DLKASVWQK 224 D +VW Sbjct: 302 DFNCNVWDA 310 >6EMK-B nrPDB Length = 303 Score = 64.0 bits (154), Expect = 1e-10, Method: Composition-based stats. Identities = 33/205 (16%), Positives = 65/205 (31%), Gaps = 30/205 (14%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPD-GKLVTVGRDLK 218 V F DN + T DG ++VW V S +K H + ++ + P+ G+L++ RD Sbjct: 81 VSFQQDNRWMVTSSEDGTIKVWDVRSPSIPRNYK-HNAPVNEVVIHPNQGELISCDRDGN 139 Query: 219 ASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFT-------VQIPH 271 +W + C P+ L+ + + + Sbjct: 140 IRIWDLGE---------------------NQCTHQLTPEDDTSLQSLSMASDGSMLAAAN 178 Query: 272 KRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFS 331 + D S+ P+ ++ + +S L + + ++ Sbjct: 179 TKGNCYVWEMPNHTDASHLKPVTKFRAHSTYITRILLSSDVKHLATCSADHTARVWSIDD 238 Query: 332 LQCLYYVREAHGIVVTDVAFLPEKG 356 L + H V D AF + Sbjct: 239 DFKLETTLDGHQRWVWDCAFSADSA 263 Score = 51.3 bits (121), Expect = 8e-07, Method: Composition-based stats. Identities = 18/85 (21%), Positives = 25/85 (29%), Gaps = 7/85 (8%) Query: 163 NHDNTLLATGGTDGYVRVWKVPS-LEKVLEFKAHEGEIEDLALGPDGK-LVTVGRDLKAS 220 + D LAT D RVW + + H+ + D A D LVT D Sbjct: 216 SSDVKHLATCSADHTARVWSIDDDFKLETTLDGHQRWVWDCAFSADSAYLVTASSDHYVR 275 Query: 221 VWQKD-----QLVTQLHWQENGPTF 240 +W + H Sbjct: 276 LWDLSTREIVRQYGGHHKGAVCVAL 300 Score = 50.9 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 32/255 (12%), Positives = 79/255 (30%), Gaps = 38/255 (14%) Query: 166 NTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQK- 224 + +L + G D +R W+ + + + ++ L + D KL+ ++ Sbjct: 2 SVILVSAGYDHTIRFWEALTGVCSRTIQHSDSQVNRLEITNDKKLLATAGHQNVRLYDIR 61 Query: 225 ----DQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIP---------- 270 + + + + N + S + ++++ V+ P Sbjct: 62 TTNPNPVASFEGHRGNVTSVSFQQDNRWM----VTSSEDGTIKVWDVRSPSIPRNYKHNA 117 Query: 271 -------HKRLRQPPPC----YLTAWDGSNFLPLRTKSCGHEV-VSCLDVSESGTFLGLG 318 H + C + WD + + + L ++ G+ L Sbjct: 118 PVNEVVIHPNQGELISCDRDGNIRIWDLGENQCTHQLTPEDDTSLQSLSMASDGSMLAAA 177 Query: 319 TVTGSVAIYI------AFSLQCLYYVREAHGIVVTDVAFLPEKGRGPELLGSHETALFSV 372 G+ ++ A L+ + R AH +T + + H ++S+ Sbjct: 178 NTKGNCYVWEMPNHTDASHLKPVTKFR-AHSTYITRILLSSDVKHLATCSADHTARVWSI 236 Query: 373 AVDSRCQLHLLPSRR 387 D + + L +R Sbjct: 237 DDDFKLETTLDGHQR 251 Score = 41.3 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 14/44 (31%), Positives = 23/44 (52%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALG 205 F+ D+ L T +D YVR+W + + E V ++ H +AL Sbjct: 258 FSADSAYLVTASSDHYVRLWDLSTREIVRQYGGHHKGAVCVALN 301 >6ID0-T nrPDB Length = 514 Score = 64.0 bits (154), Expect = 1e-10, Method: Composition-based stats. Identities = 31/232 (13%), Positives = 68/232 (29%), Gaps = 7/232 (3%) Query: 163 NHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDLKASV 221 N TG D +++W + S + L H + + + + + G D + Sbjct: 213 EPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKC 272 Query: 222 WQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCY 281 W + H+ + + + + R++ V+ Sbjct: 273 WDLEYNKVIRHYHGHLSAV-YGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTN 331 Query: 282 LTAWDGSNFLPLRTKSCGHE-VVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYVRE 340 A + + H+ + D+ T + L SV + Y Sbjct: 332 AVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPRH--YTFAS 389 Query: 341 AHGIVVTDVAFLPEKGRGPELLGSHETALFSVAVDSRCQLHLLPSRRSVPVW 392 + F P+ G + L H + ++ V+S L ++ +W Sbjct: 390 GSPDNIKQWKF-PD-GSFIQNLSGHNAIINTLTVNSDGVLVSGADNGTMHLW 439 Score = 51.3 bits (121), Expect = 7e-07, Method: Composition-based stats. Identities = 22/126 (17%), Positives = 41/126 (32%), Gaps = 10/126 (7%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKA 219 V + + A+G D ++ WK P + H I L + DG LV+ + Sbjct: 378 VVLHPRHYTFASGSPDN-IKQWKFPDGSFIQNLSGHNAIINTLTVNSDGVLVSGADNGTM 436 Query: 220 SVWQKDQLVT--QLHWQENGPTFSSTPYRYQACRFGQ------VPDQPAGLRLFTVQIPH 271 +W ++H + S + AC F Q + ++++ Sbjct: 437 HLWDWRTGYNFQRVHAAVQPGSLDSESGIF-ACAFDQSESRLLTAEADKTIKVYREDDTA 495 Query: 272 KRLRQP 277 P Sbjct: 496 TEETHP 501 >3JB9-L nrPDB Length = 340 Score = 64.0 bits (154), Expect = 1e-10, Method: Composition-based stats. Identities = 44/250 (17%), Positives = 80/250 (32%), Gaps = 55/250 (22%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK--LVTVGRDLKA 219 ++ D+ ++ +D ++ W S +K+ + K H G + L + G L +V D Sbjct: 101 WSRDSRVVYCSSSDTHLMSWDAVSGQKIRKHKGHAGVVNALDVLKVGSELLTSVSDDCTM 160 Query: 220 SVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPH-----KRL 274 VW +E P + Q + ++++ ++ H K Sbjct: 161 KVWDSRSKDCIKTIEEKYPLTAVAIA--QQGTQVFIGGIDGAIKIWDLRNNHCSHVLKGH 218 Query: 275 RQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDV-------------------------- 308 + + DGS+ L + V DV Sbjct: 219 KDIITSLAISKDGSSLLSNSMDNT----VRIFDVKPFASAQRQLQIFEGAIHGQEHNLLG 274 Query: 309 ---SESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEKGRGPELLGSH 365 S + F+G G+ +V ++ A L YV H V V F P H Sbjct: 275 VAWSRNSRFVGAGSSDKNVYVWSATGD--LRYVLPGHEGSVNHVDFHP-----------H 321 Query: 366 ETALFSVAVD 375 + + S + D Sbjct: 322 QDIILSCSSD 331 Score = 46.6 bits (109), Expect = 2e-05, Method: Composition-based stats. Identities = 11/67 (16%), Positives = 27/67 (40%), Gaps = 2/67 (2%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDLK 218 V ++ ++ + G +D V VW + + HEG + + P ++ + D Sbjct: 275 VAWSRNSRFVGAGSSDKNVYVWS-ATGDLRYVLPGHEGSVNHVDFHPHQDIILSCSSDRT 333 Query: 219 ASVWQKD 225 + + + Sbjct: 334 IFLGELN 340 >5FVM-C nrPDB Length = 303 Score = 62.1 bits (149), Expect = 4e-10, Method: Composition-based stats. Identities = 37/217 (17%), Positives = 77/217 (35%), Gaps = 20/217 (9%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPD-GKLVTVGRDLK 218 + F +N + + DG ++VW V S +K H + ++A+ P+ G+L++ +D Sbjct: 81 IAFQQENRWMVSSSEDGTIKVWDVRSPSVQRNYK-HNAPVNEVAIHPNQGELISCDQDGN 139 Query: 219 ASVWQK--DQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQ 276 +W +Q QL ++N P S + + ++ + PH Sbjct: 140 IRIWDLGENQCTNQLTPEDNTPLQSLSVAS--DGSMLVAGNNKGNCYVWRM--PHHT--- 192 Query: 277 PPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLY 336 D S P+ + ++ + +S L + + ++ L Sbjct: 193 ---------DASTLEPVTKFKSHTKYITRVLLSADVKNLATCSADHTARVWNIEDNYQLE 243 Query: 337 YVREAHGIVVTDVAFLPEKGRGPELLGSHETALFSVA 373 + H V D AF + H L+ ++ Sbjct: 244 TTLDGHQRWVWDCAFSADSAYLVTACSDHYVRLWDLS 280 Score = 50.1 bits (118), Expect = 2e-06, Method: Composition-based stats. Identities = 18/153 (11%), Positives = 52/153 (33%), Gaps = 13/153 (8%) Query: 166 NTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQK- 224 + +LA+ G D +R W+ + + + ++ L + D K + L ++ Sbjct: 2 SVILASAGYDHTIRFWEALTGVCSRTIQHADSQVNRLEITSDKKYLAAAGHLHVRLYDIR 61 Query: 225 ----DQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIP--HKRLRQPP 278 + + + + N + + + ++++ V+ P + + Sbjct: 62 SNNPNPVSSFEGHKGNVTSIAFQQENRWMVS----SSEDGTIKVWDVRSPSVQRNYKHNA 117 Query: 279 PCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSES 311 P A + + G+ + D+ E+ Sbjct: 118 PVNEVAIHPNQGELISCDQDGN--IRIWDLGEN 148 Score = 45.9 bits (107), Expect = 4e-05, Method: Composition-based stats. Identities = 27/181 (14%), Positives = 61/181 (33%), Gaps = 21/181 (11%) Query: 146 AVQTDFSSD-PLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGE-IEDLA 203 +VQ ++ + P+ +V + + L + DG +R+W + + + + ++ L+ Sbjct: 108 SVQRNYKHNAPVNEV-AIHPNQGELISCDQDGNIRIWDLGENQCTNQLTPEDNTPLQSLS 166 Query: 204 LGPDGKLVTVGRDLKAS-VWQKDQLVTQLHWQENG--PTFSSTPYRYQACRFGQVPDQ-- 258 + DG ++ G + VW+ H + P + R D Sbjct: 167 VASDGSMLVAGNNKGNCYVWRMP-----HHTDASTLEPVTKFKSHTKYITRVLLSADVKN 221 Query: 259 ------PAGLRLFTVQIPHKRLRQPPPCYLTAWD-GSNFLPLRTKS-CGHEVVSCLDVSE 310 R++ ++ ++ WD + + C V D+S Sbjct: 222 LATCSADHTARVWNIEDNYQLETTLDGHQRWVWDCAFSADSAYLVTACSDHYVRLWDLST 281 Query: 311 S 311 S Sbjct: 282 S 282 Score = 43.2 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 42/210 (20%), Positives = 79/210 (37%), Gaps = 22/210 (10%) Query: 5 RAPEL---YRAPFPLYALQVDPSTGLLIAAGGGGAAKTGIKNGVHFLQLELINGRLSASL 61 R+P + Y+ P+ + + P+ G LI+ G +++ + + Sbjct: 105 RSPSVQRNYKHNAPVNEVAIHPNQGELISCDQDGN-----------IRIWDLGENQCTNQ 153 Query: 62 LHSHDTETRATMNLALAGDILAAGQD-AHCQLLRFQAHQQQGNKAEKAGSKEQGPRQRKG 120 L D ++++A G +L AG + +C + R H K + Sbjct: 154 LTPEDNTPLQSLSVASDGSMLVAGNNKGNCYVWRMPHHTDASTLEPVTKFKSHTKYITRV 213 Query: 121 AAPAEKK----CGAETQHEGLELRVENLQAVQTDFSSDPLQKVVC-FNHDNTLLATGGTD 175 A+ K C A+ H +E+ ++T C F+ D+ L T +D Sbjct: 214 LLSADVKNLATCSAD--HTARVWNIEDNYQLETTLDGHQRWVWDCAFSADSAYLVTACSD 271 Query: 176 GYVRVWKVPSLEKVLEFKAHEGEIEDLALG 205 YVR+W + + E V ++ H +AL Sbjct: 272 HYVRLWDLSTSEIVRQYGGHHKGAVCVALN 301 >6N9G-C nrPDB Length = 353 Score = 61.7 bits (148), Expect = 6e-10, Method: Composition-based stats. Identities = 31/153 (20%), Positives = 54/153 (35%), Gaps = 7/153 (4%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPD---GKLVTVGRDLK 218 F + + + T DG +W V S + + F H ++ L L P V+ G D K Sbjct: 161 FTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKK 220 Query: 219 ASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPP 278 A VW ++ + +S Y Y + A RL+ ++ + Sbjct: 221 AMVWDMRSGQCVQAFETHESDVNSVRY-YPSGDAFASGSDDATCRLYDLRADREVAIYSK 279 Query: 279 PCYLTAWDGSNF-LPLRTKSCGHE--VVSCLDV 308 + +F L R G+ ++ DV Sbjct: 280 ESIIFGASSVDFSLSGRLLFAGYNDYTINVWDV 312 Score = 57.4 bits (137), Expect = 1e-08, Method: Composition-based stats. Identities = 30/178 (16%), Positives = 53/178 (29%), Gaps = 28/178 (15%) Query: 158 KVVCFN----HDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDG-KLVT 212 V+C + +GG D VW + S + V F+ HE ++ + P G + Sbjct: 197 DVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDVNSVRYYPSGDAFAS 256 Query: 213 VGRDLKASVWQ--KDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIP 270 D ++ D+ V + SS + R + + Sbjct: 257 GSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSG-RLLFAGYNDYTINV------ 309 Query: 271 HKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYI 328 WD + VS L VS GT G+ ++ ++ Sbjct: 310 --------------WDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRVWA 353 Score = 46.6 bits (109), Expect = 2e-05, Method: Composition-based stats. Identities = 31/217 (14%), Positives = 64/217 (29%), Gaps = 11/217 (5%) Query: 187 EKVLEFKAHEGEIEDLALGPDGK-LVTVGRDLKASVWQKDQLVTQLHWQENGPTFSSTPY 245 + K H ++ + D + +V+ +D K VW + + Y Sbjct: 54 KTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAY 113 Query: 246 RYQACRFGQVPDQPAGLRLFTVQ-------IPHKRLRQPPPCYLTAWDGSNFLPLRTKSC 298 C ++ + K+ YL+A +N + Sbjct: 114 APSGCA-IACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTAS 172 Query: 299 GHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEKGRG 358 G + DV ESG L G+ + + + + G + + G+ Sbjct: 173 GDGTCALWDV-ESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQC 231 Query: 359 PELLGSHETALFSVAVDSRCQLHLLPSRR-SVPVWLL 394 + +HE+ + SV S + ++ L Sbjct: 232 VQAFETHESDVNSVRYYPSGDAFASGSDDATCRLYDL 268 Score = 43.2 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 50/251 (19%), Positives = 79/251 (31%), Gaps = 52/251 (20%) Query: 157 QKVVCFN--HDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVG 214 KV+C + D + + DG V VW + K + A P G + G Sbjct: 64 NKVLCMDWCKDKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCAIACG 123 Query: 215 R-DLKASVW----QKDQLVTQLHWQENGPTFSSTPYRYQACRFG------QVPDQPAGLR 263 D K SV+ K++ + + + AC F Sbjct: 124 GLDNKCSVYPLTFDKNENM-----AAKKKSVAMHTNYLSACSFTNSDMQILTASGDGTCA 178 Query: 264 LFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDV--SESGTFLGLGTVT 321 L WD + L++ V CLD+ SE+G G Sbjct: 179 L--------------------WDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCD 218 Query: 322 GSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEKGRGPELLGSHETALFSVAVDSRCQLH 381 ++ S QC+ E H V V + P A S + D+ C+L+ Sbjct: 219 KKAMVWDMRSGQCV-QAFETHESDVNSVRYYPSG-----------DAFASGSDDATCRLY 266 Query: 382 LLPSRRSVPVW 392 L + R V ++ Sbjct: 267 DLRADREVAIY 277 >6GMH-W nrPDB Length = 305 Score = 61.3 bits (147), Expect = 8e-10, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 30/65 (46%), Gaps = 1/65 (1%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK-LVTVGRDLK 218 + ++ D LA+G DG + ++ + + + + + H I L PD + LVT D Sbjct: 154 IAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGY 213 Query: 219 ASVWQ 223 ++ Sbjct: 214 IKIYD 218 Score = 57.4 bits (137), Expect = 1e-08, Method: Composition-based stats. Identities = 29/197 (14%), Positives = 66/197 (33%), Gaps = 31/197 (15%) Query: 165 DNTLLATGGTDGYVRVWKV--PSLEKVLEFKAHEGEIEDLALGPDGKLVTVGR-DLKASV 221 ++ + TG D V+VWK L+ + H+ + + + + D + Sbjct: 31 NSETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRL 90 Query: 222 WQKD---QLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPP 278 W + Q+ + + T + +P V + +F V+ K Sbjct: 91 WDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGK----VNIFGVESGKKE----- 141 Query: 279 PCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYV 338 + + + + S G +L G + G + I+ + + L+ + Sbjct: 142 ---------------YSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTL 186 Query: 339 REAHGIVVTDVAFLPEK 355 E H + + + F P+ Sbjct: 187 -EGHAMPIRSLTFSPDS 202 Score = 53.6 bits (127), Expect = 1e-07, Method: Composition-based stats. Identities = 24/114 (21%), Positives = 43/114 (37%), Gaps = 8/114 (7%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGR-DLKAS 220 F+ D+ LATG G V ++ V S +K I +A PDGK + G D + Sbjct: 114 FSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIIN 173 Query: 221 VWQKDQ---LVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPH 271 ++ L T + + +P + ++++ VQ + Sbjct: 174 IFDIATGKLLHTLEGHAMPIRSLTFSPDS----QLLVTASDDGYIKIYDVQHAN 223 Score = 53.6 bits (127), Expect = 2e-07, Method: Composition-based stats. Identities = 32/254 (12%), Positives = 75/254 (29%), Gaps = 49/254 (19%) Query: 163 NHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK-LVTVGRDLKASV 221 +H + A+ D ++R+W + + +++ A + LA PD + L T K ++ Sbjct: 73 SHTLPIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNI 132 Query: 222 WQKD---QLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPP 278 + + + + + + + +P + +F + Sbjct: 133 FGVESGKKEYSLDTRGKFILSIAYSPDGKYLAS----GAIDGIINIFDI----------- 177 Query: 279 PCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYV 338 + L T + L S L + G + IY L Sbjct: 178 ---------ATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHAN-LAGT 227 Query: 339 REAHGIVVTDVAFLPE-------------------KGRGPELLGSHETALFSVAVDSRC- 378 H V +VAF P+ H+ ++ V + Sbjct: 228 LSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGS 287 Query: 379 QLHLLPSRRSVPVW 392 ++ + + + ++ Sbjct: 288 KIVSVGDDQEIHIY 301 Score = 32.4 bits (72), Expect = 0.42, Method: Composition-based stats. Identities = 18/65 (27%), Positives = 33/65 (50%), Gaps = 1/65 (1%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDG-KLVTVGRDLK 218 V F D+T + +D V+VW V + V F H+ ++ + +G K+V+VG D + Sbjct: 238 VAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQE 297 Query: 219 ASVWQ 223 ++ Sbjct: 298 IHIYD 302 >3MKQ-A nrPDB Length = 814 Score = 60.9 bits (146), Expect = 9e-10, Method: Composition-based stats. Identities = 30/191 (15%), Positives = 57/191 (29%), Gaps = 28/191 (14%) Query: 150 DFSSDP-LQKVVCFNHDNTLLATGGTDGYVRVWKVPS-LEKVLEFKAHEGEIEDLALGPD 207 DF + P + + + + +G D V++W + F+ HE + +A P Sbjct: 92 DFEAHPDYIRSIAVHPTKPYVLSGSDDLTVKLWNWENNWALEQTFEGHEHFVMCVAFNPK 151 Query: 208 --GKLVTVGRDLKASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLF 265 + D VW Q STP F Q G+ Sbjct: 152 DPSTFASGCLDRTVKVWSLGQ---------------STPN------FTLTTGQERGVNYV 190 Query: 266 T---VQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTG 322 + + + WD + T VS + + G+ G Sbjct: 191 DYYPLPDKPYMITASDDLTIKIWDYQTKSCVATLEGHMSNVSFAVFHPTLPIIISGSEDG 250 Query: 323 SVAIYIAFSLQ 333 ++ I+ + + + Sbjct: 251 TLKIWNSSTYK 261 Score = 59.7 bits (143), Expect = 2e-09, Method: Composition-based stats. Identities = 35/204 (17%), Positives = 68/204 (33%), Gaps = 27/204 (13%) Query: 168 LLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDLKASVWQKDQ 226 + G D +RV+ + EKV++F+AH I +A+ P V + DL +W + Sbjct: 69 WIIVGSDDFRIRVFNYNTGEKVVDFEAHPDYIRSIAVHPTKPYVLSGSDDLTVKLWNWE- 127 Query: 227 LVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWD 286 + + + + F + P + W Sbjct: 128 ------------------NNWALEQTFEGHEHFVMCVAFNPKDPSTFASGCLDRTVKVWS 169 Query: 287 GSNFLPLRTKSCGHEV-VSCLDVS--ESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHG 343 P T + G E V+ +D ++ + ++ I+ + C+ + E H Sbjct: 170 LGQSTPNFTLTTGQERGVNYVDYYPLPDKPYMITASDDLTIKIWDYQTKSCVATL-EGHM 228 Query: 344 IVVTDVAFLPEKGRGPELLGSHET 367 V+ F P P ++ E Sbjct: 229 SNVSFAVFHPTL---PIIISGSED 249 Score = 39.3 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 10/58 (17%), Positives = 22/58 (37%), Gaps = 2/58 (3%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK--LVTVGRDL 217 F+ ++ +G DG +++W + + +A P G+ + G D Sbjct: 236 FHPTLPIIISGSEDGTLKIWNSSTYKVEKTLNVGLERSWCIATHPTGRKNYIASGFDN 293 >2YNP-A nrPDB Length = 604 Score = 60.9 bits (146), Expect = 9e-10, Method: Composition-based stats. Identities = 30/191 (15%), Positives = 57/191 (29%), Gaps = 28/191 (14%) Query: 150 DFSSDP-LQKVVCFNHDNTLLATGGTDGYVRVWKVPS-LEKVLEFKAHEGEIEDLALGPD 207 DF + P + + + + +G D V++W + F+ HE + +A P Sbjct: 92 DFEAHPDYIRSIAVHPTKPYVLSGSDDLTVKLWNWENNWALEQTFEGHEHFVMCVAFNPK 151 Query: 208 --GKLVTVGRDLKASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLF 265 + D VW Q STP F Q G+ Sbjct: 152 DPSTFASGCLDRTVKVWSLGQ---------------STPN------FTLTTGQERGVNYV 190 Query: 266 T---VQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTG 322 + + + WD + T VS + + G+ G Sbjct: 191 DYYPLPDKPYMITASDDLTIKIWDYQTKSCVATLEGHMSNVSFAVFHPTLPIIISGSEDG 250 Query: 323 SVAIYIAFSLQ 333 ++ I+ + + + Sbjct: 251 TLKIWNSSTYK 261 Score = 59.7 bits (143), Expect = 2e-09, Method: Composition-based stats. Identities = 35/204 (17%), Positives = 68/204 (33%), Gaps = 27/204 (13%) Query: 168 LLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDLKASVWQKDQ 226 + G D +RV+ + EKV++F+AH I +A+ P V + DL +W + Sbjct: 69 WIIVGSDDFRIRVFNYNTGEKVVDFEAHPDYIRSIAVHPTKPYVLSGSDDLTVKLWNWE- 127 Query: 227 LVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWD 286 + + + + F + P + W Sbjct: 128 ------------------NNWALEQTFEGHEHFVMCVAFNPKDPSTFASGCLDRTVKVWS 169 Query: 287 GSNFLPLRTKSCGHEV-VSCLDVS--ESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHG 343 P T + G E V+ +D ++ + ++ I+ + C+ + E H Sbjct: 170 LGQSTPNFTLTTGQERGVNYVDYYPLPDKPYMITASDDLTIKIWDYQTKSCVATL-EGHM 228 Query: 344 IVVTDVAFLPEKGRGPELLGSHET 367 V+ F P P ++ E Sbjct: 229 SNVSFAVFHPTL---PIIISGSED 249 Score = 39.3 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 10/58 (17%), Positives = 22/58 (37%), Gaps = 2/58 (3%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK--LVTVGRDL 217 F+ ++ +G DG +++W + + +A P G+ + G D Sbjct: 236 FHPTLPIIISGSEDGTLKIWNSSTYKVEKTLNVGLERSWCIATHPTGRKNYIASGFDN 293 >5WYJ-BC nrPDB Length = 817 Score = 60.9 bits (146), Expect = 1e-09, Method: Composition-based stats. Identities = 26/161 (16%), Positives = 46/161 (28%), Gaps = 22/161 (13%) Query: 163 NHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGP-DGKLVTVGRDLKASV 221 + ++++ AT D ++W + + E H+ + D++ D L T D + Sbjct: 500 SPNDSIFATASYDKTCKIWNLENGELEATLANHKRGLWDVSFCQYDKLLATSSGDKTVKI 559 Query: 222 WQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCY 281 W D T Q C F Q Sbjct: 560 WSLDTF-------SVMKTLEGHTNAVQRCSFINKQKQLISC--------------GADGL 598 Query: 282 LTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTG 322 + WD S+ L+T + + L G + G Sbjct: 599 IKIWDCSSGECLKTLDGHNNRLWALSTMNDGDMIVSADADG 639 Score = 58.2 bits (139), Expect = 7e-09, Method: Composition-based stats. Identities = 19/100 (19%), Positives = 33/100 (33%), Gaps = 8/100 (8%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLAL-GPDGKLVTVGRDLK 218 V F + LLAT D V++W + + + + H ++ + +L++ G D Sbjct: 539 VSFCQYDKLLATSSGDKTVKIWSLDTFSVMKTLEGHTNAVQRCSFINKQKQLISCGADGL 598 Query: 219 ASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQ 258 +W E T R A D Sbjct: 599 IKIWDCSS-------GECLKTLDGHNNRLWALSTMNDGDM 631 Score = 54.7 bits (130), Expect = 6e-08, Method: Composition-based stats. Identities = 33/272 (12%), Positives = 68/272 (25%), Gaps = 68/272 (25%) Query: 154 DPLQKVVCFNHDNTLLATGGTDGYVRVW----KVPSLEKVLEFKAHEGEIEDLALGPDGK 209 D L + D +AT D VW + ++ H + + L Sbjct: 389 DLLNSLDA-TEDGLWIATASKDNTAIVWRYNENSCKFDIYAKYIGHSAAVTAVGLPNIVS 447 Query: 210 ------LVTVGRDLKASVW-------------QKDQLVTQLHWQENGPTFSSTPYRYQAC 250 L+T DL W K T+ +++ S +P Sbjct: 448 KGYPEFLLTASNDLTIKKWIIPKPTASMDVQIIKVSEYTRHAHEKDINALSVSPND---- 503 Query: 251 RFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSE 310 +++ ++ WD + + Sbjct: 504 SIFATASYDKTCKIWNLENGELEATLANHKRGL-WD-------------------VSFCQ 543 Query: 311 SGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAF-LPEK-------------- 355 L + +V I+ + + E H V +F +K Sbjct: 544 YDKLLATSSGDKTVKIWSLDTFS-VMKTLEGHTNAVQRCSFINKQKQLISCGADGLIKIW 602 Query: 356 ----GRGPELLGSHETALFSVAVDSRCQLHLL 383 G + L H L++++ + + + Sbjct: 603 DCSSGECLKTLDGHNNRLWALSTMNDGDMIVS 634 Score = 51.7 bits (122), Expect = 6e-07, Method: Composition-based stats. Identities = 14/63 (22%), Positives = 26/63 (41%), Gaps = 1/63 (1%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDLKAS 220 F + L + G DG +++W S E + H + L+ DG ++ + D Sbjct: 583 FINKQKQLISCGADGLIKIWDCSSGECLKTLDGHNNRLWALSTMNDGDMIVSADADGVFQ 642 Query: 221 VWQ 223 W+ Sbjct: 643 FWK 645 Score = 51.7 bits (122), Expect = 6e-07, Method: Composition-based stats. Identities = 17/65 (26%), Positives = 31/65 (47%), Gaps = 7/65 (10%) Query: 168 LLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLAL-------GPDGKLVTVGRDLKAS 220 LLA+G T+G V+VW + + + + H + L + P L++ GRD + Sbjct: 162 LLASGDTNGMVKVWDLVKRKCLHTLQEHTSAVRGLDIIEVPDNDEPSLNLLSGGRDDIIN 221 Query: 221 VWQKD 225 +W + Sbjct: 222 LWDFN 226 Score = 46.3 bits (108), Expect = 2e-05, Method: Composition-based stats. Identities = 21/83 (25%), Positives = 30/83 (36%), Gaps = 5/83 (6%) Query: 163 NHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK-----LVTVGRDL 217 + +TLLA GGTDG + V + + FK H G I L L + + Sbjct: 111 DSTSTLLAVGGTDGSIIVVDIENGYITHSFKGHGGTISSLKFYGQLNSKIWLLASGDTNG 170 Query: 218 KASVWQKDQLVTQLHWQENGPTF 240 VW + QE+ Sbjct: 171 MVKVWDLVKRKCLHTLQEHTSAV 193 >3FM0-A nrPDB Length = 345 Score = 59.7 bits (143), Expect = 2e-09, Method: Composition-based stats. Identities = 39/241 (16%), Positives = 74/241 (30%), Gaps = 53/241 (21%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLE--KVLEF-KAHEGEIEDLALGPDGKLVTVGR-DL 217 +N TLLA+ G D +R+W + H+ + +A P G + D Sbjct: 24 WNPAGTLLASCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASFDA 83 Query: 218 KASVWQKDQ-----LVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHK 272 +W+K+Q + T + + + P + + ++ V Sbjct: 84 TTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSG----NLLATCSRDKSVWVWEVD---- 135 Query: 273 RLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSL 332 + + + + + V + S L + +V +Y Sbjct: 136 -------------EEDEYECVSVLNSHTQDVKHVVWHPSQELLASASYDDTVKLY----- 177 Query: 333 QCLYYVREAHGIVVTDVAFLPEKGRGPELLGSHETALFSVAVDSRCQ-LHLLPSRRSVPV 391 RE V L HE+ ++S+A D Q L R+V + Sbjct: 178 ------REEEDDWV-----------CCATLEGHESTVWSLAFDPSGQRLASCSDDRTVRI 220 Query: 392 W 392 W Sbjct: 221 W 221 Score = 55.5 bits (132), Expect = 4e-08, Method: Composition-based stats. Identities = 41/266 (15%), Positives = 76/266 (28%), Gaps = 64/266 (24%) Query: 160 VCFNHDNTLLATGGTDGYVRVW--KVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRD 216 V ++ LA+ D +W E V + HE E++ +A P G L+ T RD Sbjct: 67 VAWSPCGNYLASASFDATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRD 126 Query: 217 LKASVWQKDQ--------LVTQLH-------WQENGPTFSSTPY-----------RYQAC 250 VW+ D+ ++ W + +S Y C Sbjct: 127 KSVWVWEVDEEDEYECVSVLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVC 186 Query: 251 RFGQVP--------------------DQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNF 290 +R++ +P +W Sbjct: 187 CATLEGHESTVWSLAFDPSGQRLASCSDDRTVRIWRQYLPGNEQGVACSGSDPSWKCICT 246 Query: 291 LPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIY--------IAFSLQCLYYVREAH 342 L +++ C +G L ++ ++ + ++ +AH Sbjct: 247 LSGFHSRTIYDIAWC---QLTGA-LATACGDDAIRVFQEDPNSDPQQPTFSLTAHLHQAH 302 Query: 343 GIVVTDVAFLPEKGRGPELLGSHETA 368 V VA+ P++ P LL S Sbjct: 303 SQDVNCVAWNPKE---PGLLASCSDD 325 Score = 38.6 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 27/120 (22%), Positives = 36/120 (30%), Gaps = 26/120 (21%) Query: 299 GHEVVSCL--DVSESGTFLGLGTVTGSVAIYIAF--SLQCLYYVREAHGIVVTDVAFLP- 353 H C + +GT L + I+ S C + E H V VA+ P Sbjct: 13 AHPDSRCWFLAWNPAGTLLASCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPC 72 Query: 354 --------------------EKGRGPELLGSHETALFSVAVDSRCQLHLLPSR-RSVPVW 392 + L HE + SVA L SR +SV VW Sbjct: 73 GNYLASASFDATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVW 132 Score = 36.2 bits (82), Expect = 0.023, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 27/69 (39%), Gaps = 11/69 (15%) Query: 169 LATGGTDGYVRVWK--------VPSLEKVLEFK-AHEGEIEDLALGPD--GKLVTVGRDL 217 LAT D +RV++ P+ AH ++ +A P G L + D Sbjct: 267 LATACGDDAIRVFQEDPNSDPQQPTFSLTAHLHQAHSQDVNCVAWNPKEPGLLASCSDDG 326 Query: 218 KASVWQKDQ 226 + + W+ + Sbjct: 327 EVAFWKYQR 335 >5Y88-O nrPDB Length = 451 Score = 58.6 bits (140), Expect = 5e-09, Method: Composition-based stats. Identities = 34/237 (14%), Positives = 71/237 (29%), Gaps = 16/237 (6%) Query: 167 TLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDLKASVWQKD 225 L + D V+ W + + + ++ H + +++ P L+ T GRD +W Sbjct: 195 PYLFSVSEDKTVKCWDLEKNQIIRDYYGHLSGVRTVSIHPTLDLIATAGRDSVIKLWDMR 254 Query: 226 Q---LVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYL 282 ++T + + TP Q A +RL+ V Sbjct: 255 TRIPVITLVGHKGPINQVQCTPVDPQVVS----SSTDATVRLWDVVAGKTMKVLTHHKRS 310 Query: 283 TAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAH 342 + S + + ++E G+ L + I Q Sbjct: 311 VRATALHPKEFSVASACTDDIRSWGLAE-GSLLTNFESEKTGIINTLSINQDDVLFAGGD 369 Query: 343 GIVVT----DVAFLPEKGRGPELLGSHETA--LFSVAVDSRCQLHLLP-SRRSVPVW 392 V++ + E++GS E + D + + +S+ +W Sbjct: 370 NGVLSFYDYKSGHKYQSLATREMVGSLEGERSVLCSTFDKTGLRLITGEADKSIKIW 426 Score = 53.6 bits (127), Expect = 2e-07, Method: Composition-based stats. Identities = 13/63 (20%), Positives = 25/63 (39%), Gaps = 1/63 (1%) Query: 165 DNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDLKASVWQ 223 DN TG D ++VW + + + H + D+A+ + +V D W Sbjct: 151 DNEWFITGSNDTTMKVWDLATGKLKTTLAGHVMTVRDVAVSDRHPYLFSVSEDKTVKCWD 210 Query: 224 KDQ 226 ++ Sbjct: 211 LEK 213 Score = 50.9 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 16/67 (23%), Positives = 31/67 (46%), Gaps = 1/67 (1%) Query: 158 KVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGP-DGKLVTVGRD 216 + V + L+AT G D +++W + + V+ H+G I + P D ++V+ D Sbjct: 228 RTVSIHPTLDLIATAGRDSVIKLWDMRTRIPVITLVGHKGPINQVQCTPVDPQVVSSSTD 287 Query: 217 LKASVWQ 223 +W Sbjct: 288 ATVRLWD 294 Score = 39.3 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 28/217 (12%), Positives = 62/217 (28%), Gaps = 36/217 (16%) Query: 181 WKVPSLEKVLEFKAHEGEIEDLALGP--DGKLVTVGRDLKASVWQK--DQLVTQLHWQEN 236 W P + H G + +A+ P + +T D VW +L T L Sbjct: 125 WHAP-WKLSRVINGHLGWVRCVAIDPVDNEWFITGSNDTTMKVWDLATGKLKTTLAGHVM 183 Query: 237 GPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTK 296 + R+ + + ++ + ++ + Sbjct: 184 TVRDVAVSDRH---PYLFSVSEDKTVKCWDLEKNQ---------------------IIRD 219 Query: 297 SCGH-EVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEK 355 GH V + + + + + ++ + + + H + V P Sbjct: 220 YYGHLSGVRTVSIHPTLDLIATAGRDSVIKLWDMRTRIPVITLV-GHKGPINQVQCTPVD 278 Query: 356 GRGPELLGSHETALFSV--AVDSRCQLHLLPSRRSVP 390 P+++ S A + V + L +RSV Sbjct: 279 ---PQVVSSSTDATVRLWDVVAGKTMKVLTHHKRSVR 312 Score = 34.7 bits (78), Expect = 0.070, Method: Composition-based stats. Identities = 20/107 (18%), Positives = 40/107 (37%), Gaps = 17/107 (15%) Query: 149 TDFSSDPLQKVVCFNHD-NTLLATGGTDGYVRVWK---------VPSLEKVLEFKAHEGE 198 T+F S+ + + + + +L GG +G + + + + E V + E Sbjct: 343 TNFESEKTGIINTLSINQDDVLFAGGDNGVLSFYDYKSGHKYQSLATREMVGSLEG-ERS 401 Query: 199 IEDLALGPDG-KLVTVGRDLKASVWQKDQLVT-----QLHWQENGPT 239 + G +L+T D +W++D+ T L W N Sbjct: 402 VLCSTFDKTGLRLITGEADKSIKIWKQDETATKESEPGLAWNPNLSA 448 >5GAN-H nrPDB Length = 465 Score = 58.6 bits (140), Expect = 5e-09, Method: Composition-based stats. Identities = 32/170 (18%), Positives = 66/170 (38%), Gaps = 16/170 (9%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKL-VTVGRDLKAS 220 ++ + + D R+W + +++L + H+ + L+ DG L + G D + Sbjct: 273 YHPSGKFIGSASHDMTWRLWDASTHQELLLQEGHDKGVFSLSFQCDGSLVCSGGMDSLSM 332 Query: 221 VWQK---DQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQP 277 +W +++T + T + +P YQ G + V KR Sbjct: 333 LWDIRSGSKVMTLAGHSKPIYTVAWSPNGYQVATGGGDG-------IINVWDIRKRDEGQ 385 Query: 278 PPCYLTAWDGSNFLPLRTKSCGHEVVSC-----LDVSESGTFLGLGTVTG 322 L + + + G ++VSC ++V S T+L +G++ G Sbjct: 386 LNQILAHRNIVTQVRFSKEDGGKKLVSCGYDNLINVYSSDTWLKMGSLAG 435 Score = 57.0 bits (136), Expect = 1e-08, Method: Composition-based stats. Identities = 51/324 (15%), Positives = 106/324 (32%), Gaps = 32/324 (9%) Query: 91 QLLRFQAHQQQGNKAEKAGSKEQGPRQRKGAAPAEKKCGAETQHEGLELRVENLQAVQT- 149 +LL + Q+ E AGS+ + + + T +L+V N Q +Q Sbjct: 151 ELLSRRTELQRMANLELAGSQLVSTKPISAVSLSTDDMVVATGSWAGDLQVLNSQTLQPL 210 Query: 150 ----DFSSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLE----KVLEFKAHEGEIED 201 D + + N + + DG ++ ++ + E + + HE I D Sbjct: 211 TQKLDSHVGKIGAIDWHPDSNNQMISCAEDGLIKNFQYSNEEGGLRLLGDLVGHERRISD 270 Query: 202 LALGPDGKLV-TVGRDLKASVWQK---DQLVTQLHWQENGPTFSSTPYRYQACRFGQVPD 257 + P GK + + D+ +W +L+ Q + + S C Sbjct: 271 VKYHPSGKFIGSASHDMTWRLWDASTHQELLLQEGHDKGVFSLSFQCDGSLVCS----GG 326 Query: 258 QPAGLRLFTVQIPHKRLR---QPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDV-----S 309 + L+ ++ K + P Y AW N + T G +++ D+ Sbjct: 327 MDSLSMLWDIRSGSKVMTLAGHSKPIYTVAW-SPNGYQVAT-GGGDGIINVWDIRKRDEG 384 Query: 310 ESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEKGRGPELLGSHETAL 369 + L + V + L V + ++ + + L H + Sbjct: 385 QLNQILAHRNIVTQVRFSKEDGGKKL--VSCGYDNLIN--VYSSDTWLKMGSLAGHTDKI 440 Query: 370 FSVAVDSRCQLHLLPS-RRSVPVW 392 S+ + + + RS+ +W Sbjct: 441 ISLDISNNSHFLVSGGWDRSIKLW 464 Score = 38.6 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 13/59 (22%), Positives = 23/59 (38%), Gaps = 1/59 (1%) Query: 166 NTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK-LVTVGRDLKASVWQ 223 L + G D + V+ + K+ H +I L + + LV+ G D +W Sbjct: 407 GKKLVSCGYDNLINVYSSDTWLKMGSLAGHTDKIISLDISNNSHFLVSGGWDRSIKLWN 465 Score = 28.9 bits (63), Expect = 3.8, Method: Composition-based stats. Identities = 5/20 (25%), Positives = 13/20 (65%) Query: 163 NHDNTLLATGGTDGYVRVWK 182 ++++ L +GG D +++W Sbjct: 446 SNNSHFLVSGGWDRSIKLWN 465 >5WYK-BB nrPDB Length = 943 Score = 57.8 bits (138), Expect = 8e-09, Method: Composition-based stats. Identities = 58/339 (17%), Positives = 105/339 (30%), Gaps = 91/339 (26%) Query: 123 PAEKKCGAETQHEGLELRVENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRVWK 182 P EK+ T L+ LQ +TD S + DN LLAT +G +++W Sbjct: 368 PYEKR--DPTSPAPLKTHTIELQGQRTDVRSIDISD------DNKLLATAS-NGSLKIWN 418 Query: 183 VPSLEKVLEFK-----------------------------------------AHEGEIED 201 + + + + F+ AH+ I Sbjct: 419 IKTHKCIRTFECGYALTCKFLPGGLLVILGTRNGELQLFDLASSSLLDTIEDAHDAAIWS 478 Query: 202 LALGPDGK-LVTVGRDLKASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPA 260 L L DGK LVT D W + G P Sbjct: 479 LDLTSDGKRLVTGSADKTVKFWD----FKVENSLVPGTKNKFLP--------VLKLHHDT 526 Query: 261 GLRLFTVQIPHKRLRQPPPCYLTAWDGS------NFLPLRTKSCGHEV-VSCLDVSESGT 313 L L + + ++ D + + + GH++ V +D+S Sbjct: 527 TLELTDDILCVRVSPDDRYLAISLLDNTVKVFFLDSMKFYLSLYGHKLPVLSIDISFDSK 586 Query: 314 FLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPE------------------- 354 + + ++ I+ C + AH + +V FLP+ Sbjct: 587 MIITSSADKNIKIWGLDFGDC-HKSLFAHQDSIMNVKFLPQSHNFFSCSKDAVVKYWDGE 645 Query: 355 KGRGPELLGSHETALFSVAVDSRCQLHLLPSR-RSVPVW 392 K + L +H++ ++++AV + + S S+ +W Sbjct: 646 KFECIQKLYAHQSEVWALAVATDGGFVVSSSHDHSIRIW 684 Score = 57.4 bits (137), Expect = 1e-08, Method: Composition-based stats. Identities = 22/121 (18%), Positives = 46/121 (38%), Gaps = 13/121 (10%) Query: 167 TLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQKD- 225 L + DG +++W + + + + AH GE LA+ D L+T G D + +W+ D Sbjct: 175 DWLISTSKDGMIKLWDLKTHQCIETHIAHTGECWGLAV-KDDLLITTGTDSQVKIWKLDI 233 Query: 226 ------QLVTQL-----HWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRL 274 +T++ ++ G F + + + F ++ + Sbjct: 234 ENDKMGGKLTEMGIFEKQSKQRGLKIEFITNSSDKTSFFYIQNADKTIETFRIRKEEEIA 293 Query: 275 R 275 R Sbjct: 294 R 294 Score = 56.3 bits (134), Expect = 2e-08, Method: Composition-based stats. Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 1/63 (1%) Query: 163 NHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDG-KLVTVGRDLKASV 221 + D LLA G DG ++VW + S +L F H+ I L G +L++ +D V Sbjct: 88 HKDTDLLAVGYADGVIKVWDLMSKTVLLNFNGHKAAITLLQFDGTGTRLISGSKDSNIIV 147 Query: 222 WQK 224 W Sbjct: 148 WDL 150 Score = 48.6 bits (114), Expect = 6e-06, Method: Composition-based stats. Identities = 15/66 (22%), Positives = 28/66 (42%), Gaps = 1/66 (1%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKL-VTVGRDLKAS 220 F + + D V+ W E + + AH+ E+ LA+ DG V+ D Sbjct: 623 FLPQSHNFFSCSKDAVVKYWDGEKFECIQKLYAHQSEVWALAVATDGGFVVSSSHDHSIR 682 Query: 221 VWQKDQ 226 +W++ + Sbjct: 683 IWEETE 688 Score = 41.6 bits (96), Expect = 7e-04, Method: Composition-based stats. Identities = 12/63 (19%), Positives = 26/63 (41%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASV 221 F+ T L +G D + VW + + + ++H+ I + L++ +D + Sbjct: 129 FDGTGTRLISGSKDSNIIVWDLVGEVGLYKLRSHKDSITGFWCQGEDWLISTSKDGMIKL 188 Query: 222 WQK 224 W Sbjct: 189 WDL 191 >3ODT-A nrPDB Length = 313 Score = 56.7 bits (135), Expect = 2e-08, Method: Composition-based stats. Identities = 19/104 (18%), Positives = 42/104 (40%), Gaps = 2/104 (1%) Query: 165 DNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQK 224 D+ + DG +++ + + + + ++ HE + + L P+G +V+ G D +W K Sbjct: 194 DDGHFISCSNDGLIKLVDMHTGDVLRTYEGHESFVYCIKLLPNGDIVSCGEDRTVRIWSK 253 Query: 225 DQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQ 268 + L P S + V +R+F+ + Sbjct: 254 EN--GSLKQVITLPAISIWSVDCMSNGDIIVGSSDNLVRIFSQE 295 Score = 50.9 bits (120), Expect = 9e-07, Method: Composition-based stats. Identities = 16/74 (21%), Positives = 32/74 (43%), Gaps = 6/74 (8%) Query: 158 KVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIED---LALGPDGKLVTVG 214 V + + ++ +G D +VWK V +AH + D ++ + K +T Sbjct: 106 NVCSLSFQDGVVISGSWDKTAKVWK--EGSLVYNLQAHNASVWDAKVVSFSEN-KFLTAS 162 Query: 215 RDLKASVWQKDQLV 228 D +WQ D+++ Sbjct: 163 ADKTIKLWQNDKVI 176 Score = 42.0 bits (97), Expect = 5e-04, Method: Composition-based stats. Identities = 39/246 (15%), Positives = 75/246 (30%), Gaps = 43/246 (17%) Query: 187 EKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQKDQLVTQ---LHWQENGPTFSST 243 + K H+ ++ D+ D K+ +V RD +W KD Q + Sbjct: 9 QLSATLKGHDQDVRDVVAVDDSKVASVSRDGTVRLWSKDDQWLGTVVYTGQGFLNSVCYD 68 Query: 244 PYRYQACRFGQVPDQPAGLRLFTVQ-------------IPHKRLRQPPPCYLTAWD---- 286 + + FG G+ LF Q +WD Sbjct: 69 SEK-ELLLFGGKDTMINGVPLFATSGEDPLYTLIGHQGNVCSLSFQDGVVISGSWDKTAK 127 Query: 287 ----GSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYI------AFS----- 331 GS L+ + + SE+ FL + ++ ++ FS Sbjct: 128 VWKEGSLVYNLQAHNASVWDAKVVSFSEN-KFL-TASADKTIKLWQNDKVIKTFSGIHND 185 Query: 332 -LQCLYYVREAHGIVVTDVAFLP----EKGRGPELLGSHETALFSVAVDSRCQLHLLPSR 386 ++ L V + H I ++ + G HE+ ++ + + + Sbjct: 186 VVRHLAVVDDGHFISCSNDGLIKLVDMHTGDVLRTYEGHESFVYCIKLLPNGDIVSCGED 245 Query: 387 RSVPVW 392 R+V +W Sbjct: 246 RTVRIW 251 Score = 40.9 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 8/58 (13%), Positives = 21/58 (36%) Query: 169 LATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQKDQ 226 + + G D VR+W + I + +G ++ D ++ +++ Sbjct: 239 IVSCGEDRTVRIWSKENGSLKQVITLPAISIWSVDCMSNGDIIVGSSDNLVRIFSQEK 296 >4V7E-Bg nrPDB Length = 380 Score = 56.7 bits (135), Expect = 2e-08, Method: Composition-based stats. Identities = 33/111 (29%), Positives = 45/111 (40%), Gaps = 6/111 (5%) Query: 117 QRKGAAPAEKKCGAETQHEGLELRVENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDG 176 QR G + C G +L+V N + + D + P+ V F+ LL G ++G Sbjct: 262 QRFGTGSDDGTCRLFDMRTGHQLQVYNREPDRND-NELPIVTSVAFSISGRLLFAGYSNG 320 Query: 177 YVRVWKVPSLEKVLEF----KAHEGEIEDLALGPDGK-LVTVGRDLKASVW 222 VW E VL +HEG I L L DG L T D +W Sbjct: 321 DCYVWDTLLAEMVLNLGTLQNSHEGRISCLGLSSDGSALCTGSWDKNLKIW 371 Score = 54.3 bits (129), Expect = 9e-08, Method: Composition-based stats. Identities = 43/275 (15%), Positives = 76/275 (27%), Gaps = 59/275 (21%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDG-KLVTVGRDLKAS 220 + + + + DG + VW + +K K H + + A P+G + G D S Sbjct: 74 WTPEKNWIVSASQDGRLIVWNALTSQKTHAIKLHCPWVMECAFAPNGQSVACGGLDSACS 133 Query: 221 VWQK------------DQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQ 268 ++ +++T SS Y L+ V Sbjct: 134 IFNLSSQADRDGNMPVSRVLTGHKGYA-----SSCQYVPDQETRLITGSGDQTCVLWDVT 188 Query: 269 IPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYI 328 + GS F T +V+S S + G+ +V ++ Sbjct: 189 TGQRISIF----------GSEFPSGHT----ADVLSLSINSLNANMFISGSCDTTVRLWD 234 Query: 329 AFSLQCLYYVREAHGIVVTDVAFLPE-----------KGRGPELLGSHETALF------- 370 H + V F P+ R ++ H+ ++ Sbjct: 235 LRITSRAVRTYHGHEGDINSVKFFPDGQRFGTGSDDGTCRLFDMRTGHQLQVYNREPDRN 294 Query: 371 --------SVAVDSRCQLHLLP-SRRSVPVWLLLL 396 SVA +L S VW LL Sbjct: 295 DNELPIVTSVAFSISGRLLFAGYSNGDCYVWDTLL 329 >6QDV-o nrPDB Length = 513 Score = 56.3 bits (134), Expect = 3e-08, Method: Composition-based stats. Identities = 28/135 (20%), Positives = 52/135 (38%), Gaps = 14/135 (10%) Query: 151 FSSDPLQKVVCFNHDNT---LLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLAL-GP 206 F++ + V FN D L G +D + W + S E V E+ H G + + Sbjct: 304 FTNRKVPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDE 363 Query: 207 DGKLVTVGRDLKASVWQKDQLVTQLHWQEN----GPTFSSTPY-RYQACRFGQVPDQPAG 261 + + V+ D VW+ D V + E P + +P ++ AC+ Sbjct: 364 NRRFVSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVTLSPNGKWLACQ-----SMDNQ 418 Query: 262 LRLFTVQIPHKRLRQ 276 + +F Q + ++ Sbjct: 419 ILIFGAQNRFRLNKK 433 Score = 52.0 bits (123), Expect = 5e-07, Method: Composition-based stats. Identities = 34/203 (16%), Positives = 64/203 (31%), Gaps = 29/203 (14%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK----LVTVGR 215 +CFN T + D Y+++W + + + F + + PD V Sbjct: 272 ICFNTAGTQFLSAAYDRYLKLWDTETGQCISRF-TNRKVPYCVKFNPDEDKQNLFVAGMS 330 Query: 216 DLKASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLR 275 D K W + + ++ + + RF D LR++ IP Sbjct: 331 DKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRFVSTSD-DKSLRVWEWDIPVDFKY 389 Query: 276 QPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCL 335 P + +P T S +G +L ++ + I+ A + L Sbjct: 390 IAEPSMHS-------MPAVTL------------SPNGKWLACQSMDNQILIFGAQNRFRL 430 Query: 336 --YYVREAH--GIVVTDVAFLPE 354 + + H V F P+ Sbjct: 431 NKKKIFKGHMVAGYACQVDFSPD 453 Score = 49.3 bits (116), Expect = 3e-06, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 28/64 (43%), Gaps = 2/64 (3%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPD--GKLVTVGRDLKA 219 F+ D + + +G +G + +W + + FKAH+ P K++T G D Sbjct: 450 FSPDMSYVISGDGNGKLNIWDWKTTKLYSRFKAHDKVCIGAVWHPHETSKVITCGWDGLI 509 Query: 220 SVWQ 223 +W Sbjct: 510 KLWD 513 Score = 47.0 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 12/66 (18%), Positives = 25/66 (37%), Gaps = 2/66 (3%) Query: 162 FNHDNTLLATGGTDGYVRVWKV-PSLEKVLEFKAHEGEIEDLALGPDG-KLVTVGRDLKA 219 F LL + D +++W+V + F H + D+ G + ++ D Sbjct: 231 FPLSGHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYL 290 Query: 220 SVWQKD 225 +W + Sbjct: 291 KLWDTE 296 >5YZG-W nrPDB Length = 579 Score = 56.3 bits (134), Expect = 3e-08, Method: Composition-based stats. Identities = 28/135 (20%), Positives = 52/135 (38%), Gaps = 14/135 (10%) Query: 151 FSSDPLQKVVCFNHDNT---LLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLAL-GP 206 F++ + V FN D L G +D + W + S E V E+ H G + + Sbjct: 370 FTNRKVPYCVKFNPDEDKQNLFVAGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDE 429 Query: 207 DGKLVTVGRDLKASVWQKDQLVTQLHWQEN----GPTFSSTPY-RYQACRFGQVPDQPAG 261 + + V+ D VW+ D V + E P + +P ++ AC+ Sbjct: 430 NRRFVSTSDDKSLRVWEWDIPVDFKYIAEPSMHSMPAVTLSPNGKWLACQ-----SMDNQ 484 Query: 262 LRLFTVQIPHKRLRQ 276 + +F Q + ++ Sbjct: 485 ILIFGAQNRFRLNKK 499 Score = 52.0 bits (123), Expect = 5e-07, Method: Composition-based stats. Identities = 34/203 (16%), Positives = 64/203 (31%), Gaps = 29/203 (14%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK----LVTVGR 215 +CFN T + D Y+++W + + + F + + PD V Sbjct: 338 ICFNTAGTQFLSAAYDRYLKLWDTETGQCISRF-TNRKVPYCVKFNPDEDKQNLFVAGMS 396 Query: 216 DLKASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLR 275 D K W + + ++ + + RF D LR++ IP Sbjct: 397 DKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRFVSTSD-DKSLRVWEWDIPVDFKY 455 Query: 276 QPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCL 335 P + +P T S +G +L ++ + I+ A + L Sbjct: 456 IAEPSMHS-------MPAVTL------------SPNGKWLACQSMDNQILIFGAQNRFRL 496 Query: 336 --YYVREAH--GIVVTDVAFLPE 354 + + H V F P+ Sbjct: 497 NKKKIFKGHMVAGYACQVDFSPD 519 Score = 49.3 bits (116), Expect = 3e-06, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 28/64 (43%), Gaps = 2/64 (3%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPD--GKLVTVGRDLKA 219 F+ D + + +G +G + +W + + FKAH+ P K++T G D Sbjct: 516 FSPDMSYVISGDGNGKLNIWDWKTTKLYSRFKAHDKVCIGAVWHPHETSKVITCGWDGLI 575 Query: 220 SVWQ 223 +W Sbjct: 576 KLWD 579 Score = 47.0 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 12/66 (18%), Positives = 25/66 (37%), Gaps = 2/66 (3%) Query: 162 FNHDNTLLATGGTDGYVRVWKV-PSLEKVLEFKAHEGEIEDLALGPDG-KLVTVGRDLKA 219 F LL + D +++W+V + F H + D+ G + ++ D Sbjct: 297 FPLSGHLLLSCSMDCKIKLWEVYGERRCLRTFIGHSKAVRDICFNTAGTQFLSAAYDRYL 356 Query: 220 SVWQKD 225 +W + Sbjct: 357 KLWDTE 362 >5OQL-d nrPDB Length = 446 Score = 55.9 bits (133), Expect = 3e-08, Method: Composition-based stats. Identities = 43/246 (17%), Positives = 81/246 (32%), Gaps = 20/246 (8%) Query: 160 VCFNHDN-TLLATGGTDGYVRVWKVPSL-EKVLEFKAHEGEIEDLALGPDGKLVTVGRDL 217 +C + ++ +A+G DG V+VW + + E+ AH ++ L D KL++ D Sbjct: 72 MCKDKNSLNCIASGSGDGVVKVWDLTTRDEETWRVAAHNNIVKGLTFTNDKKLLSCATDG 131 Query: 218 KASVWQ----KDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGL-RLFTVQIPHK 272 +W WQE GP S + +R G R++ ++ Sbjct: 132 I-KLWDPYASPSNTTPIATWQEGGPYTSLSFHR---SANTFAASSGQGCIRIWDLEHSTA 187 Query: 273 RLRQPPPCYLTAWDGSNFLPLRTKSCGHEV----VSCLDVSESGTFLGLGTVTGSVAI-Y 327 P ++ F + T G + D+ + + I + Sbjct: 188 GQAIQWPSFVDTITDVCFNQVETSVIGSVATDRSIILFDLRTNMPVIKTVLHFACNRIVF 247 Query: 328 IAFSLQCLYYVREAHGIVVTDVAFLPEKGRGPELLGSHETALFSVAVDSRCQLHLLPS-R 386 L E H I + D + + H A+ V + + S Sbjct: 248 NPMEAMNLAVASEDHNIYIFDAR---NFDKALNIQKGHVAAVMDVEFSPTGEELVSGSYD 304 Query: 387 RSVPVW 392 R++ +W Sbjct: 305 RTIRLW 310 Score = 40.1 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 12/68 (17%), Positives = 26/68 (38%), Gaps = 6/68 (8%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDL---ALGPDGKLV-TVGRDL 217 F+ L +G D +R+W+ + + H ++ + D K + T D Sbjct: 291 FSPTGEELVSGSYDRTIRLWRRDAGHSRDVY--HTKRMQRVFRTMWTMDSKYILTGSDDG 348 Query: 218 KASVWQKD 225 +W+ + Sbjct: 349 NVRLWRAN 356 >5WLC-LU nrPDB Length = 489 Score = 55.9 bits (133), Expect = 3e-08, Method: Composition-based stats. Identities = 42/267 (15%), Positives = 87/267 (32%), Gaps = 60/267 (22%) Query: 169 LATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALG--------PDGK----LVTVGRD 216 LATG DG ++ W + + E+ + FKAH G + L + PD K +++ D Sbjct: 83 LATGSADGVIKYWNMSTREEFVSFKAHYGLVTGLCVTQPRFHDKKPDLKSQNFMLSCSDD 142 Query: 217 LKASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQ 276 +W + + SS V ++ +R F + + + Sbjct: 143 KTVKLWSIN-------VDDYSNKNSSDNDS--------VTNEEGLIRTFDGESAFQGIDS 187 Query: 277 PPPCYLTA--------WDGSNFLPLRTKSCGHEVVSCLDVSESGT-FLGLGTVTGSVAIY 327 A WD + P+ S G + ++ L +++ T L S+ +Y Sbjct: 188 HRENSTFATGGAKIHLWDVNRLKPVSDLSWGADNITSLKFNQNETDILASTGSDNSIVLY 247 Query: 328 IAFSLQCLYYVREAHGIVVTDVAFLPEKG---------------------RGPELLGSHE 366 + + + + + + P + R + H Sbjct: 248 DLRTNSPTQKIVQT--MRTNAICWNPMEAFNFVTANEDHNAYYYDMRNLSRSLNVFKDHV 305 Query: 367 TALFSVAVDSRCQLHLLPS-RRSVPVW 392 +A+ V + S +S+ ++ Sbjct: 306 SAVMDVDFSPTGDEIVTGSYDKSIRIY 332 Score = 43.9 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 28/206 (13%), Positives = 57/206 (27%), Gaps = 48/206 (23%) Query: 165 DNTLLATGGTDGYVRVWKV-----------------PSLEKVLEFKAHEGEIEDLALGPD 207 + + D V++W + + F + + Sbjct: 132 SQNFMLSCSDDKTVKLWSINVDDYSNKNSSDNDSVTNEEGLIRTFDGESAFQGIDSHREN 191 Query: 208 GKLVTVGRDLKASVWQKDQL--VTQLHWQ-ENGPTFSSTPYRYQACRFGQVPDQPAGLRL 264 T G K +W ++L V+ L W +N + + L Sbjct: 192 STFATGG--AKIHLWDVNRLKPVSDLSWGADNITSLKFNQNETDILAST---GSDNSIVL 246 Query: 265 FTVQI--PHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHE-------------------VV 303 + ++ P +++ Q W+ T + H V Sbjct: 247 YDLRTNSPTQKIVQTMRTNAICWNPMEAFNFVTANEDHNAYYYDMRNLSRSLNVFKDHVS 306 Query: 304 SCLDV--SESGTFLGLGTVTGSVAIY 327 + +DV S +G + G+ S+ IY Sbjct: 307 AVMDVDFSPTGDEIVTGSYDKSIRIY 332 Score = 38.9 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 11/65 (16%), Positives = 23/65 (35%), Gaps = 6/65 (9%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIED---LALGPDGKL-VTVGRDL 217 F+ + TG D +R++K + H ++ + D K ++ D Sbjct: 313 FSPTGDEIVTGSYDKSIRIYKTNHGHSREIY--HTKRMQHVFQVKYSMDSKYIISGSDDG 370 Query: 218 KASVW 222 +W Sbjct: 371 NVRLW 375 >6BX3-A nrPDB Length = 314 Score = 55.5 bits (132), Expect = 4e-08, Method: Composition-based stats. Identities = 47/266 (17%), Positives = 86/266 (32%), Gaps = 29/266 (10%) Query: 155 PLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TV 213 P ++ C++ D +AT D V + + + F H + L G L+ T Sbjct: 56 PFSEL-CWSPDGQCIATASDDFSVEIIHLSYG-LLHTFIGHTAPVISLTFNRKGNLLFTS 113 Query: 214 GRDLKASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKR 273 D +W + S +R+F + H Sbjct: 114 SMDESIKIWDTLNGSLMKTISAHSEAVVSVDVPMNDSSILSSGSYDGLIRIFDAETGHCL 173 Query: 274 LRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQ 333 Y W N G +S + SE+ +L + ++ G V I+ Sbjct: 174 KTLT---YDKDWKREN---------GVVPISQVKFSENARYLLVKSLDGVVKIWDCIG-G 220 Query: 334 CLYYVREAHGIVVTDVA-------FLPEKGRGPELLGSHET-ALFSVAVDSRCQLHLLPS 385 C+ + + + PE G P ++ +E ++ D++ L LL Sbjct: 221 CVVRTFQVQPLEKGVLHHSCGMDFLNPEDGSTPLVISGYENGDIYCWNSDTKSLLQLLDG 280 Query: 386 ---RRSVPVWLLLLLCVGLIIVTILL 408 S PV + + C G I+ ++ L Sbjct: 281 SLYHHSSPV--MSIHCFGNIMCSLAL 304 Score = 39.3 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 14/80 (17%), Positives = 32/80 (40%), Gaps = 9/80 (11%) Query: 153 SDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEF------KAHEG--EIEDLAL 204 S+ + V +D+++L++G DG +R++ + + K G I + Sbjct: 137 SEAVVSVDVPMNDSSILSSGSYDGLIRIFDAETGHCLKTLTYDKDWKRENGVVPISQVKF 196 Query: 205 GPDGKLVTVGR-DLKASVWQ 223 + + + V D +W Sbjct: 197 SENARYLLVKSLDGVVKIWD 216 Score = 39.3 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 32/185 (17%), Positives = 58/185 (31%), Gaps = 37/185 (20%) Query: 200 EDLALGPDGKLVTVGRDLKASVWQKDQ------LVTQLHWQENGPTFSSTPYRYQACRFG 253 + PDG+ + + + L ++ ++ LVT +P C Sbjct: 16 TCAKISPDGQFLAITQGLNILIYDINRRTVSQTLVTSH--ARPFSELCWSPDG--QCIAT 71 Query: 254 QVPDQPAGLRLFTVQIPHKRLRQPPPCYLTA-------------------WDGSNFLPLR 294 D + + + H + P WD N ++ Sbjct: 72 ASDDFSVEIIHLSYGLLHTFIGHTAPVISLTFNRKGNLLFTSSMDESIKIWDTLNGSLMK 131 Query: 295 TKSCGHEVVSCLDVS-ESGTFLGLGTVTGSVAIYIAFSLQCLYYV-------REAHGIVV 346 T S E V +DV + L G+ G + I+ A + CL + RE + + Sbjct: 132 TISAHSEAVVSVDVPMNDSSILSSGSYDGLIRIFDAETGHCLKTLTYDKDWKRENGVVPI 191 Query: 347 TDVAF 351 + V F Sbjct: 192 SQVKF 196 Score = 30.1 bits (66), Expect = 1.8, Method: Composition-based stats. Identities = 23/119 (19%), Positives = 40/119 (33%), Gaps = 17/119 (14%) Query: 155 PLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAH--EGEIEDLA-----LGP- 206 P+ +V F+ + L DG V++W V F+ E + + L P Sbjct: 190 PISQVK-FSENARYLLVKSLDGVVKIWDCIGGCVVRTFQVQPLEKGVLHHSCGMDFLNPE 248 Query: 207 DGK---LVTVGRDLKASVWQKD-----QLVTQLHWQENGPTFSSTPYRYQACRFGQVPD 257 DG +++ + W D QL+ + + P S + C D Sbjct: 249 DGSTPLVISGYENGDIYCWNSDTKSLLQLLDGSLYHHSSPVMSIHCFGNIMCSLALNGD 307 >5OQL-J nrPDB Length = 912 Score = 55.5 bits (132), Expect = 4e-08, Method: Composition-based stats. Identities = 45/245 (18%), Positives = 86/245 (35%), Gaps = 43/245 (17%) Query: 163 NHDNTLLATGGTDGYVRVWKVPS-----LEKVLEFK--AHEGEIEDLALGPDGKL-VTVG 214 +H L +G D +V+ +P + + AH+ +I L + P+GKL + Sbjct: 504 DHPPAFLISGSQDRFVQKRDIPRQLQKGGKLTSSLRRLAHDKDINALDISPNGKLFASAS 563 Query: 215 RDLKASVWQKDQL-----VTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQI 269 +D +W ++L + T P + Q G+ L Sbjct: 564 QDKTVKIWDVEKLEVQGILRGHKRG--VWTVRFAPLNTPVIQGEQGSVSGRGVVLTGSGD 621 Query: 270 PHKRLRQPPPCYLTAWDGSNFLPLRT-KSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYI 328 +L W+ S++ +RT + H V+ + + S ++T + + Sbjct: 622 KTIKL----------WNLSDYTCIRTFEGHSHNVLKVVWLHISRD----DSITKTKVQFA 667 Query: 329 AFSLQCLYYVREAHGIVVTDVAFLPEKGRGPELLGSHETALFSVAVDSRCQLHLL-PSRR 387 + L V +A+ G L +HE L+++AV S+ + S Sbjct: 668 SAGADTLVKVWDAN------------TGETECTLDNHEDRLWTLAVHSKTNILASAGSDS 715 Query: 388 SVPVW 392 V W Sbjct: 716 KVTFW 720 Score = 47.0 bits (110), Expect = 1e-05, Method: Composition-based stats. Identities = 41/274 (14%), Positives = 80/274 (29%), Gaps = 61/274 (22%) Query: 169 LATGGTDGYVRVWKVPSLEK-------VLEFKAHEGEIEDLALGP-DGKLVTVGRDLKAS 220 LA G DG +R++ + + +AHE ++ +A P L++ RD + Sbjct: 198 LAWGTQDGRIRIFDLYKRTTTPVYADPKRKKEAHESNVQCIAYSPEQHALLSGSRDKTMT 257 Query: 221 VW---QKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQ- 276 +W T + E + G LR++ H+ ++ Sbjct: 258 LWLWRDGIWQGTPMLRHELLESVGFLNEGKWMYSAGTSGV----LRIWDTTTHHEITKKQ 313 Query: 277 ------------------------------------PPPCYLTAWDGSNFLPLRTKSCGH 300 P +++ +G P R S H Sbjct: 314 DAKSEGEAILSAVSLPERSLILCAQADFTLVLYRVPSPADVVSSSEGILLEPFRRISGTH 373 Query: 301 EVVSCLDV-SESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEKGRGP 359 + + L + + + T + + I +A+ + G Sbjct: 374 DEILDLTYILPDQSMMAIATNSEDIRIVSV-------KDAQAYSEDNAECRSGSYFGHDV 426 Query: 360 ELLGSHETALFSVAVDSRCQLHLLPSR-RSVPVW 392 LL HE + S+ VD S+ + +W Sbjct: 427 ALLKGHEDIVMSLDVDWSGHWIASGSKDNTARLW 460 Score = 43.6 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 40/256 (15%), Positives = 85/256 (33%), Gaps = 39/256 (15%) Query: 156 LQKVVCFNHDNTLLATGGTDGYVRVWKVPS---LEKVLEFKAHEGEIEDLALGPDGKLVT 212 L + V F ++ + + GT G +R+W + + K + K+ I P+ L+ Sbjct: 276 LLESVGFLNEGKWMYSAGTSGVLRIWDTTTHHEITKKQDAKSEGEAILSAVSLPERSLIL 335 Query: 213 VGR-DLKASVWQKD-----------------QLVTQLHWQENGPTFSSTPYRYQACRFGQ 254 + D +++ + ++ H E P + Sbjct: 336 CAQADFTLVLYRVPSPADVVSSSEGILLEPFRRISGTH-DEILDLTYILPDQSMMAIATN 394 Query: 255 VPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTF 314 D +R+ +V+ C ++ G + + ++V LDV SG + Sbjct: 395 SED----IRIVSVKDAQAYSEDNAECRSGSYFGHD---VALLKGHEDIVMSLDVDWSGHW 447 Query: 315 LGLGTVTGSVAIY---IAFSLQCLYYVREAHGIVVTDVAFLPEKGRGPELLGSHETALFS 371 + G+ + ++ A + Y V H V VA P+++ + F Sbjct: 448 IASGSKDNTARLWRVDPANNSYTCYAVFTGHLESVGAVAL-------PKVVPPANSEAFK 500 Query: 372 VAVDSRCQLHLLPSRR 387 +D + S+ Sbjct: 501 NPLDHPPAFLISGSQD 516 Score = 36.2 bits (82), Expect = 0.026, Method: Composition-based stats. Identities = 34/220 (15%), Positives = 75/220 (34%), Gaps = 27/220 (12%) Query: 159 VVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLAL----------GPDG 208 V+ + +TLLATG DG +++W + + L + Sbjct: 116 VLAVDRTSTLLATGAADGAIKIWDIIGGYVTHTVSGPSVLVSALHFFEIAVTAESQSSNK 175 Query: 209 KLVTVGRDLKASVWQKDQLVT--QLHWQENGPTF--------SSTPYRYQACRFGQVPDQ 258 K R + D++ + +L W ++TP R + + Sbjct: 176 KPKKGSRKGQND--DADEIASRFRLAWGTQDGRIRIFDLYKRTTTPVYADPKRKKEAHES 233 Query: 259 PAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLG 318 ++ + H L +T W + + T HE++ + G ++ Sbjct: 234 NVQCIAYSPEQ-HALLSGSRDKTMTLWLWRDGIWQGTPMLRHELLESVGFLNEGKWMYSA 292 Query: 319 TVTGSVAIYIAFSLQCLYYVREAH---GIVVTDVAFLPEK 355 +G + I+ + + ++A +++ V+ LPE+ Sbjct: 293 GTSGVLRIWDTTTHHEITKKQDAKSEGEAILSAVS-LPER 331 >4G56-B nrPDB Length = 357 Score = 54.7 bits (130), Expect = 7e-08, Method: Composition-based stats. Identities = 19/75 (25%), Positives = 33/75 (44%), Gaps = 2/75 (2%) Query: 151 FSSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGP--DG 208 + D + K + D T +GG D V+VW + + + AH E+ +A P D Sbjct: 136 YEHDDIVKTLSVFSDGTQAVSGGKDFSVKVWDLSQKAVLKSYNAHSSEVNCVAACPGKDT 195 Query: 209 KLVTVGRDLKASVWQ 223 ++ G D + +W Sbjct: 196 IFLSCGEDGRILLWD 210 Score = 33.9 bits (76), Expect = 0.11, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 30/77 (38%), Gaps = 5/77 (6%) Query: 169 LATGGTDGYVRVWKVPSLEKVLEFK----AHEGEIEDLALGPDGKL-VTVGRDLKASVWQ 223 + G V +W++ E +L K H+ ++ L++ DG V+ G+D VW Sbjct: 108 ILVASDSGAVELWEILEKESLLVNKFAKYEHDDIVKTLSVFSDGTQAVSGGKDFSVKVWD 167 Query: 224 KDQLVTQLHWQENGPTF 240 Q + + Sbjct: 168 LSQKAVLKSYNAHSSEV 184 Score = 28.2 bits (61), Expect = 6.6, Method: Composition-based stats. Identities = 20/143 (13%), Positives = 40/143 (27%), Gaps = 6/143 (4%) Query: 167 TLLATGGTDGYVRVWKV--PSLEKVLEFKAHEGEIEDLALGP--DGKLVTVGRDLKASVW 222 T+ + G DG + +W P ++F A + + P D S+ Sbjct: 195 TIFLSCGEDGRILLWDTRKPKPATRIDFCASDTIPTSVTWHPEKDDTFACGDETGNVSLV 254 Query: 223 QKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPH--KRLRQPPPC 280 + + + Y Y + F + + + + L Sbjct: 255 NIKNPDSAQTSAVHSQNITGLAYSYHSSPFLASISEDCTVAVLDADFSEVFRDLSHRDFV 314 Query: 281 YLTAWDGSNFLPLRTKSCGHEVV 303 AW + T H+V+ Sbjct: 315 TGVAWSPLDHSKFTTVGWDHKVL 337 >3JB9-g nrPDB Length = 558 Score = 54.7 bits (130), Expect = 7e-08, Method: Composition-based stats. Identities = 38/213 (17%), Positives = 70/213 (32%), Gaps = 28/213 (13%) Query: 151 FSSDPLQKVVCFNHDNTL---LATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPD 207 F+SD L V F D G D + + + S + V + H G I + + Sbjct: 348 FNSDRLTNCVKFQVDPDKPNEFLAGTADKRILQFDIRSPDIVQAYDHHLGGINSITFLEN 407 Query: 208 GK-LVTVGRDLKASVWQKDQLVTQLHWQEN----GPTFSSTPYRYQACRFGQVPDQPAGL 262 GK VT D W+ V + P + P + + Sbjct: 408 GKRFVTTSDDSSMRFWEYGTPVPIKFVADIAMHSMPRVALRPNG----KSIACQSLDNCI 463 Query: 263 RLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTG 322 +++ +++ RQ + S + G S G F+ G +G Sbjct: 464 YVYS---AYEKYRQNKKKVFKGYSCS----GYSLEVG--------FSPDGRFVFSGDSSG 508 Query: 323 SVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEK 355 + + + + + + AH V +AF P++ Sbjct: 509 NACFWDWKTCKLMAKLP-AHSGPVQSMAFHPQE 540 Score = 54.0 bits (128), Expect = 1e-07, Method: Composition-based stats. Identities = 19/118 (16%), Positives = 37/118 (31%), Gaps = 15/118 (12%) Query: 162 FNHDNTLLATGGTDGYVRVWKV-PSLEKVLEFKAHEGEIEDLALGPDG-KLVTVGRDLKA 219 F LL +G D +++W+V + F+ H I DL+ DG ++ D Sbjct: 275 FPISGHLLLSGSMDNQIKIWEVYHDRSLLRTFQGHARPIRDLSFSQDGRSFLSTSFDKTI 334 Query: 220 SVWQ--KDQLVTQLHWQENGPTFSST-----PYRYQACRFGQVPDQPAGLRLFTVQIP 270 +W + + + P + + F ++ P Sbjct: 335 KLWDTELGKCLNCFNSDRLTNCVKFQVDPDKPNEF------LAGTADKRILQFDIRSP 386 Score = 47.8 bits (112), Expect = 9e-06, Method: Composition-based stats. Identities = 18/85 (21%), Positives = 33/85 (38%), Gaps = 3/85 (3%) Query: 142 ENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIED 201 +N + V +S V F+ D + +G + G W + + + + AH G ++ Sbjct: 474 QNKKKVFKGYSCSGYSLEVGFSPDGRFVFSGDSSGNACFWDWKTCKLMAKLPAHSGPVQS 533 Query: 202 LALGPD--GKLVTVG-RDLKASVWQ 223 +A P K+ T D W Sbjct: 534 MAFHPQETSKVATSSIVDGSIKYWD 558 Score = 36.2 bits (82), Expect = 0.027, Method: Composition-based stats. Identities = 14/86 (16%), Positives = 26/86 (30%), Gaps = 10/86 (11%) Query: 189 VLEFKAHEGEIEDLALGPDGK--LVTVGRDLKASVW----QKDQLVTQLHWQENGPTFSS 242 + +K H I L P L++ D + +W + L T S Sbjct: 259 IFTWKGHTKGISCLRFFPISGHLLLSGSMDNQIKIWEVYHDRSLLRTFQGHARPIRDLSF 318 Query: 243 TPYRYQACRFGQVPDQPAGLRLFTVQ 268 + Q R ++L+ + Sbjct: 319 S----QDGRSFLSTSFDKTIKLWDTE 340 Score = 28.9 bits (63), Expect = 3.7, Method: Composition-based stats. Identities = 24/114 (21%), Positives = 46/114 (40%), Gaps = 16/114 (14%) Query: 245 YRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVS 304 + YQ + VP+ G+ L + P ++ P ++ W G + +S Sbjct: 225 FDYQNRSYMHVPN-DVGINL--SEEPGEQTCYIPKKHIFTWKGHT-----------KGIS 270 Query: 305 CLDVSE-SGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEKGR 357 CL SG L G++ + I+ + + L + H + D++F + GR Sbjct: 271 CLRFFPISGHLLLSGSMDNQIKIWEVYHDRSLLRTFQGHARPIRDLSFS-QDGR 323 >6J6H-n nrPDB Length = 455 Score = 54.3 bits (129), Expect = 9e-08, Method: Composition-based stats. Identities = 35/234 (14%), Positives = 81/234 (34%), Gaps = 12/234 (5%) Query: 165 DNTLLATGGTDGYVRVWKV-PSLEKVLEFKAHEGEIEDLALGPD-GKLVTVGRDLKASVW 222 L+ +GG D +++W E + +F+ H I+ L D ++ D +W Sbjct: 174 TGHLILSGGNDHTIKIWDFYHDYECLRDFQGHNKPIKALRFTEDCQSFLSSSFDRSVKIW 233 Query: 223 QKD--QLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPC 280 + ++ T+LH S P F L ++ L Q Sbjct: 234 DTETGKVKTRLHLNSTPADVESRPTN--PHEFIVGLSNSKILHYDDRVSENQGLVQTYDH 291 Query: 281 YLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVA---IYIAFSLQCLYY 337 +L++ + P +K + + E+ + + ++ + ++ Y+ Sbjct: 292 HLSSILALKYFPDGSKFISSSEDKTVRIWENQINVPIKQISDTAQHSMPFLNVHPSQNYF 351 Query: 338 VREAHGIVVTDVAFLPEKGRGP-ELLGSHETALF--SVAVDSRCQLHLLPSRRS 388 ++ + + P+ R P ++ H +A + S+A + +S Sbjct: 352 CAQSMDNRIYSFSLKPKYKRHPKKIFKGHSSAGYGISLAFSGDGRYICSGDSKS 405 Score = 34.7 bits (78), Expect = 0.080, Method: Composition-based stats. Identities = 18/89 (20%), Positives = 29/89 (32%), Gaps = 13/89 (14%) Query: 153 SDPLQKVVCF---NHDNTLLATGGTDGYVRVWKVP---SLEKVLEFKAHE--GEIEDLAL 204 SD Q + F + D + + + FK H G LA Sbjct: 332 SDTAQHSMPFLNVHPSQNYFCAQSMDNRIYSFSLKPKYKRHPKKIFKGHSSAGYGISLAF 391 Query: 205 GPDGKLVTVGRDLKASV----WQKDQLVT 229 DG+ + G D K+ + W +L+ Sbjct: 392 SGDGRYICSG-DSKSRLFTWDWNTSRLLN 419 Score = 32.8 bits (73), Expect = 0.29, Method: Composition-based stats. Identities = 23/165 (13%), Positives = 42/165 (25%), Gaps = 54/165 (32%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLE---------------------------------- 187 F D + D V++W + + Sbjct: 214 FTEDCQSFLSSSFDRSVKIWDTETGKVKTRLHLNSTPADVESRPTNPHEFIVGLSNSKIL 273 Query: 188 -----------KVLEFKAHEGEIEDLALGPDG-KLVTVGRDLKASVWQKDQLVTQLH--- 232 V + H I L PDG K ++ D +W+ V Sbjct: 274 HYDDRVSENQGLVQTYDHHLSSILALKYFPDGSKFISSSEDKTVRIWENQINVPIKQISD 333 Query: 233 -WQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQ 276 Q + P + P + C + F+++ +KR + Sbjct: 334 TAQHSMPFLNVHPSQNYFCA----QSMDNRIYSFSLKPKYKRHPK 374 >5OQL-L nrPDB Length = 557 Score = 53.6 bits (127), Expect = 2e-07, Method: Composition-based stats. Identities = 29/178 (16%), Positives = 52/178 (29%), Gaps = 34/178 (19%) Query: 167 TLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK----LVTVGRDLKASVW 222 T L + D VR+W +PS + F H + A P LV+ D VW Sbjct: 158 TTLMSCSDDKTVRLWDLPSNDPTRLFTGHTDYVRCGAFMPGSANSNLLVSGSYDETVRVW 217 Query: 223 QK----DQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPP 278 ++T H + + + + Sbjct: 218 DARAPGGAVMTFKHADPIEDVLPLPS------GTTLLAASGNAISVLDLVAA-------- 263 Query: 279 PCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLY 336 PLR + + V+ L ++ G + G++ G V ++ S + Sbjct: 264 ------------KPLRLITNHQKTVTSLSLASQGRRVVSGSLDGHVKVFETTSWNVVA 309 Score = 33.9 bits (76), Expect = 0.12, Method: Composition-based stats. Identities = 38/246 (15%), Positives = 75/246 (30%), Gaps = 47/246 (19%) Query: 165 DNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRD-LKASVWQ 223 N L A V ++ + E + + E + PDG+++ G D + V+ Sbjct: 69 TNDLFAV-TAGPRVEIFSIRKREPLKTIGRFDSEAHCGEIRPDGRVLVAGEDTGRMQVFD 127 Query: 224 KD---QLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPC 280 + V W + T + +RL Sbjct: 128 VGQGTRAVILKTWHIHKQPVWVTKWSPTELTTLMSCSDDKTVRL---------------- 171 Query: 281 YLTAWDGSNFLPLRTKSCGHEVVSCLDV---SESGTFLGLGTVTGSVAIYIAFSLQCLYY 337 WD + P R + + V C S + L G+ +V ++ A + Sbjct: 172 ----WDLPSNDPTRLFTGHTDYVRCGAFMPGSANSNLLVSGSYDETVRVWDARAPGG-AV 226 Query: 338 VREAHGIVVTDVAFLPE------------------KGRGPELLGSHETALFSVAVDSRCQ 379 + H + DV LP + L+ +H+ + S+++ S+ + Sbjct: 227 MTFKHADPIEDVLPLPSGTTLLAASGNAISVLDLVAAKPLRLITNHQKTVTSLSLASQGR 286 Query: 380 LHLLPS 385 + S Sbjct: 287 RVVSGS 292 >4PSX-B nrPDB Length = 401 Score = 53.6 bits (127), Expect = 2e-07, Method: Composition-based stats. Identities = 22/104 (21%), Positives = 48/104 (46%), Gaps = 7/104 (6%) Query: 139 LRVENLQAVQTDFSS----DPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEK-VLEFK 193 L++ +++A T + P + +H + LLA G D YV ++ + ++++ + Sbjct: 233 LKINDVRANNTTIDTVKCPQPFNTLAFSHHSSNLLAAAGMDSYVYLYDLRNMKEPLHHMS 292 Query: 194 AHEGEIEDLALGP--DGKLVTVGRDLKASVWQKDQLVTQLHWQE 235 HE + +L DG +V+ G D + +W Q+ + + Sbjct: 293 GHEDAVNNLEFSTHVDGVVVSSGSDNRLMMWDLKQIGAEQTPDD 336 Score = 33.5 bits (75), Expect = 0.17, Method: Composition-based stats. Identities = 12/86 (13%), Positives = 30/86 (34%), Gaps = 16/86 (18%) Query: 154 DPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSL--------------EKVLEFKAHEGEI 199 D + + H + ++ + G+D + +W + + E ++ H + Sbjct: 296 DAVNNLEFSTHVDGVVVSSGSDNRLMMWDLKQIGAEQTPDDAEDGVPELIMVHAGHRSSV 355 Query: 200 EDLALGPDGK--LVTVGRDLKASVWQ 223 D L P + + + VW+ Sbjct: 356 NDFDLNPQIPWLVASAEEENILQVWK 381 Score = 29.7 bits (65), Expect = 2.6, Method: Composition-based stats. Identities = 26/197 (13%), Positives = 57/197 (28%), Gaps = 33/197 (16%) Query: 165 DNTLLATGGTDGYVRVWKVPSL-EKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQ 223 D ++AT G ++ + L+F G + G+L++ D ++W+ Sbjct: 130 DPNIVATINGQGTTFLYSRSEGLQSTLKFHKDNGYALSFSTLVKGRLLSGSDDHTVALWE 189 Query: 224 KD---------QLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRL 274 + LH + + + + L++ V+ + Sbjct: 190 VGSGGDPTKPVRTWNDLH-SDIINDNKWHNFNKDLFG---TVSEDSLLKINDVR-ANNTT 244 Query: 275 RQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQC 334 C P T + H S L + V +Y +++ Sbjct: 245 IDTVKCP---------QPFNTLAFSH---------HSSNLLAAAGMDSYVYLYDLRNMKE 286 Query: 335 LYYVREAHGIVVTDVAF 351 + H V ++ F Sbjct: 287 PLHHMSGHEDAVNNLEF 303 >4J0W-A nrPDB Length = 343 Score = 52.8 bits (125), Expect = 2e-07, Method: Composition-based stats. Identities = 43/263 (16%), Positives = 75/263 (28%), Gaps = 47/263 (17%) Query: 163 NHDNTLLATGGTDGYVRVWKVPSLEKVLEFK-----------AHEGEIEDLALGPDGKLV 211 D++ + + D + W V S K+ H + +A+ DGK + Sbjct: 23 TPDDSAIFSAAKDCSIIKWSVESGRKLHVIPRAKKGAEGKPPGHSSHVLCMAISSDGKYL 82 Query: 212 TVGRDLKA-SVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTV-QI 269 G K +W+ + + S +R + ++++ V + Sbjct: 83 ASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTHQLYST-SHDRSVKVWNVAEN 141 Query: 270 PHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFL-------------- 315 + + A D + T V + E + Sbjct: 142 SYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRVWKIPEESQLVFYGHQGSIDCIHLI 201 Query: 316 -----GLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEKGRGPELLGSHETALF 370 G GSVA++ + L REAHG+ RG L + Sbjct: 202 NEEHMVSGADDGSVALWGLSKKRPLALQREAHGL------------RGEPGLE-QPFWIS 248 Query: 371 SVAVDSRCQLHLLPSRRSV-PVW 392 SVA L S S +W Sbjct: 249 SVAALLNTDLVATGSHSSCVRLW 271 Score = 35.1 bits (79), Expect = 0.056, Method: Composition-based stats. Identities = 37/225 (16%), Positives = 65/225 (28%), Gaps = 74/225 (32%) Query: 189 VLEFKAHEGEIEDLALGPDGKLV-TVGRDLKASVWQKDQLVTQLHWQENGPTFSSTPYRY 247 + + H+ I L + PD + + +D W Sbjct: 7 IRVLRGHQLSITCLVVTPDDSAIFSAAKDCSIIKW------------------------- 41 Query: 248 QACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLD 307 +G +L + K PP + + V C+ Sbjct: 42 ---------SVESGRKLHVIPRAKKGAEGKPPGHSSH------------------VLCMA 74 Query: 308 VSESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEKGRG--------- 358 +S G +L G + + I+ A S Q LY H V+ +AF + Sbjct: 75 ISSDGKYLASGDRSKLILIWEAQSCQHLYTFT-GHRDAVSGLAFRRGTHQLYSTSHDRSV 133 Query: 359 ----------PELLGSHETALFSV-AVDSRCQLHLLPSRRSVPVW 392 E L H+ A+ ++ A+ C + +V VW Sbjct: 134 KVWNVAENSYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRVW 178 >5N4A-A nrPDB Length = 771 Score = 52.8 bits (125), Expect = 3e-07, Method: Composition-based stats. Identities = 28/138 (20%), Positives = 42/138 (30%), Gaps = 4/138 (2%) Query: 138 ELRVENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEG 197 E +V L A TD P+ + A TDG V++ + + H+G Sbjct: 47 EQKVSTLDAYFTDMHWYPVSSKKTQAGGTDVFAVACTDGSVKILS-RTGRVEKSIEGHKG 105 Query: 198 EIEDLALGPDGK-LVTVGRDLKASVWQKDQLV--TQLHWQENGPTFSSTPYRYQACRFGQ 254 L DG L T G D +W ++ ++ T + Q C Sbjct: 106 ACISLRWSYDGTALATAGEDGSVKIWSRNGMLRSTLAQADSPVYSIVWAYDCDQLCYCTG 165 Query: 255 VPDQPAGLRLFTVQIPHK 272 L Q K Sbjct: 166 SNVVIKSLSSNAKQNAWK 183 Score = 37.8 bits (86), Expect = 0.009, Method: Composition-based stats. Identities = 23/103 (22%), Positives = 36/103 (34%), Gaps = 41/103 (39%) Query: 162 FNHDNTLLATGGTDGYVRVW---------------------------------------- 181 +++D T LAT G DG V++W Sbjct: 112 WSYDGTALATAGEDGSVKIWSRNGMLRSTLAQADSPVYSIVWAYDCDQLCYCTGSNVVIK 171 Query: 182 KVPSLEKVLEFKAHEGEIEDLALGP-DGKLVTVGRDLKASVWQ 223 + S K +KAH+G + + P + ++T G D K VW Sbjct: 172 SLSSNAKQNAWKAHDGVVLKVDWSPINHLIITGGEDCKYKVWD 214 Score = 35.1 bits (79), Expect = 0.059, Method: Composition-based stats. Identities = 16/83 (19%), Positives = 34/83 (40%), Gaps = 2/83 (2%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASV 221 ++ N L+ TGG D +VW + + + + +A P G+L VG + Sbjct: 194 WSPINHLIITGGEDCKYKVWD-SFGRLLFQSGLFDYPVTSVAWAPSGELFAVGGFNTLQL 252 Query: 222 WQK-DQLVTQLHWQENGPTFSST 243 + +++H + G + + Sbjct: 253 CDRMGWAYSKIHLNDTGSIMTLS 275 >4OWR-A nrPDB Length = 339 Score = 52.8 bits (125), Expect = 3e-07, Method: Composition-based stats. Identities = 29/144 (20%), Positives = 49/144 (34%), Gaps = 14/144 (9%) Query: 150 DFSSDPLQKVVCFNHD-----NTLLATGGTDGYVRVWKVP-SLEKVLEFKA-HEGEIEDL 202 + +S P + C + L G VR W+V S + + + + H G + D+ Sbjct: 4 EVTSSPDDSIGCLSFSPPTLPGNFLIAGSWANDVRCWEVQDSGQTIPKAQQMHTGPVLDV 63 Query: 203 ALGPDG-KLVTVGRDLKASVWQK--DQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQP 259 DG K+ T D A +W +Q + T +C Sbjct: 64 CWSDDGSKVFTASCDKTAKMWDLSSNQAIQIAQHDAPVKTIHWIKAPNYSC--VMTGSWD 121 Query: 260 AGLRLFTVQ--IPHKRLRQPPPCY 281 L+ + + P L+ P CY Sbjct: 122 KTLKFWDTRSSNPMMVLQLPERCY 145 Score = 33.9 bits (76), Expect = 0.14, Method: Composition-based stats. Identities = 14/52 (26%), Positives = 19/52 (36%), Gaps = 4/52 (7%) Query: 198 EIEDLALGP-DGKLVTVGRDLKASVWQKD---QLVTQLHWQENGPTFSSTPY 245 + +A P G L TVG D + S W KD +L T + Sbjct: 246 AVNGIAFHPVHGTLATVGSDGRFSFWDKDARTKLKTSEQLDQPISACCFNHN 297 Score = 28.5 bits (62), Expect = 5.9, Method: Composition-based stats. Identities = 11/51 (21%), Positives = 21/51 (41%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKL 210 + F+ + LAT G+DG W + K+ + + I +G + Sbjct: 250 IAFHPVHGTLATVGSDGRFSFWDKDARTKLKTSEQLDQPISACCFNHNGNI 300 >5K19-A nrPDB Length = 569 Score = 52.8 bits (125), Expect = 3e-07, Method: Composition-based stats. Identities = 23/88 (26%), Positives = 37/88 (42%), Gaps = 4/88 (4%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDLKAS 220 F+ D LA DG++RV+ S+E K++ G + + PDGK + T G D + Sbjct: 228 FSPDGKFLACVSQDGFLRVFNFDSVELHGTMKSYFGGLLCVCWSPDGKYIVTGGEDDLVT 287 Query: 221 VW---QKDQLVTQLHWQENGPTFSSTPY 245 VW + + + PY Sbjct: 288 VWSFVDCRVIARGHGHKSWVSVVAFDPY 315 Score = 47.0 bits (110), Expect = 1e-05, Method: Composition-based stats. Identities = 13/47 (27%), Positives = 20/47 (42%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGP 206 VC++ D + TGG D V VW + H+ + +A P Sbjct: 268 VCWSPDGKYIVTGGEDDLVTVWSFVDCRVIARGHGHKSWVSVVAFDP 314 Score = 29.3 bits (64), Expect = 3.6, Method: Composition-based stats. Identities = 10/33 (30%), Positives = 16/33 (48%), Gaps = 1/33 (3%) Query: 196 EGEIEDLALGPDGKLVTV-GRDLKASVWQKDQL 227 EG + + A PDGK + +D V+ D + Sbjct: 220 EGALNEFAFSPDGKFLACVSQDGFLRVFNFDSV 252 >5FA5-B nrPDB Length = 367 Score = 52.4 bits (124), Expect = 3e-07, Method: Composition-based stats. Identities = 20/122 (16%), Positives = 44/122 (36%), Gaps = 4/122 (3%) Query: 151 FSSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGP--DG 208 + D + V T +G D ++VW + + ++AH ++ +A P D Sbjct: 147 YEHDDIVSTVSVLSSGTQAVSGSKDICIKVWDLAQQVVLSSYRAHAAQVTCVAASPHKDS 206 Query: 209 KLVTVGRDLKASVWQKD--QLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFT 266 ++ D + +W + +Q+ G +S + Q D+ + L Sbjct: 207 VFLSCSEDNRILLWDTRCPKPASQIGCSAPGYLPTSLAWHPQQSEVFVFGDENGTVSLVD 266 Query: 267 VQ 268 + Sbjct: 267 TK 268 Score = 30.9 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 33/183 (18%), Positives = 59/183 (32%), Gaps = 20/183 (10%) Query: 196 EGEIEDLALGPDGKLVTVGRDLKASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQV 255 E ++E DG L+ L W + + F S + +A Sbjct: 53 ERQLEAARYRSDGALLLGASSLSGRCWAGSLWLFKDPCAAPNEGFCSAGVQTEAGVADLT 112 Query: 256 PDQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFL 315 G+ + + + + + + K ++VS + V SGT Sbjct: 113 WVGERGILVASDSGA-------VELWELDENETLIVSKFCKYEHDDIVSTVSVLSSGTQA 165 Query: 316 GLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEKGRGPELLGSHETALF-SVAV 374 G+ + ++ L R AH VT VA P H+ ++F S + Sbjct: 166 VSGSKDICIKVWDLAQQVVLSSYR-AHAAQVTCVAASP-----------HKDSVFLSCSE 213 Query: 375 DSR 377 D+R Sbjct: 214 DNR 216 Score = 28.9 bits (63), Expect = 3.7, Method: Composition-based stats. Identities = 14/88 (15%), Positives = 28/88 (31%), Gaps = 4/88 (4%) Query: 166 NTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK--LVTVGRDLKASVWQ 223 + + G +G V + S VL H + L P L ++ D +V Sbjct: 250 SEVFVFGDENGTVSLVDTKSTSCVLSSAVHSQCVTGLVFSPHSVPFLASLSEDCSLAVLD 309 Query: 224 --KDQLVTQLHWQENGPTFSSTPYRYQA 249 +L ++ + +P + Sbjct: 310 SSLSELFRSQAHRDFVRDATWSPLNHSL 337 >6ELZ-p nrPDB Length = 460 Score = 51.3 bits (121), Expect = 8e-07, Method: Composition-based stats. Identities = 15/61 (24%), Positives = 27/61 (44%), Gaps = 1/61 (1%) Query: 166 NTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQKD 225 + + +G DG VR W + S ++ H G I + + +LV+ G D +W+ Sbjct: 115 SKHIISGSYDGIVRTWDL-SGNVQKQYSGHSGPIRAVKYISNTRLVSAGNDRTLRLWKTK 173 Query: 226 Q 226 Sbjct: 174 N 174 Score = 42.0 bits (97), Expect = 5e-04, Method: Composition-based stats. Identities = 32/254 (12%), Positives = 74/254 (29%), Gaps = 49/254 (19%) Query: 147 VQTDFS--SDPLQKVVCFNHDNTLLATGGTDGYVRVW----------------------- 181 VQ +S S P++ V + NT L + G D +R+W Sbjct: 136 VQKQYSGHSGPIRAVKYIS--NTRLVSAGNDRTLRLWKTKNDDLKLTSQQQAQEDDDDEV 193 Query: 182 KVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVW-----QKDQLVTQLHWQEN 236 + + + + H+ + + + + ++++ D W + + Sbjct: 194 NIEDGKTLAILEGHKAPVVSIDVSDNSRILSASYDNSIGFWSTIYKEMTVVDPLEDINNP 253 Query: 237 GPTFSSTP-------------YRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLT 283 S+ R + P +F + Sbjct: 254 NNKISTAARKRRKLTMKDGTIRRRAPLSLLESHTAPVEQVIFDSTDNTVGYSVSQDHTIK 313 Query: 284 AWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIY---IAFSLQCLYYVRE 340 WD + T++ + ++S +S + L G+ + ++ + S + Sbjct: 314 TWDLVTARCIDTRTTSYSLLSIAQLS-TLNLLACGSSARHITLHDPRVGASSKVTQQQLI 372 Query: 341 AHGIVVTDVAFLPE 354 H V+ + PE Sbjct: 373 GHKNFVSSLDTCPE 386 Score = 32.0 bits (71), Expect = 0.55, Method: Composition-based stats. Identities = 14/69 (20%), Positives = 28/69 (40%), Gaps = 8/69 (11%) Query: 168 LLATGGTDGYVRVWKVPSLEKVLEF--------KAHEGEIEDLALGPDGKLVTVGRDLKA 219 +L +G DG V+VW V S + K ++ + +++ G+D K Sbjct: 390 ILCSGSHDGTVKVWDVRSTSPMYTITREDKSVQKGVNDKVFAVKWAEKVGIISAGQDKKI 449 Query: 220 SVWQKDQLV 228 + + D + Sbjct: 450 QINKGDNIF 458 Score = 31.6 bits (70), Expect = 0.70, Method: Composition-based stats. Identities = 14/116 (12%), Positives = 32/116 (27%), Gaps = 47/116 (40%) Query: 155 PLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKV------------------------- 189 P+++V+ + DNT+ + D ++ W + + + Sbjct: 289 PVEQVIFDSTDNTVGYSVSQDHTIKTWDLVTARCIDTRTTSYSLLSIAQLSTLNLLACGS 348 Query: 190 --------------------LEFKAHEGEIEDLALGPDGK--LVTVGRDLKASVWQ 223 + H+ + L P+ + L + D VW Sbjct: 349 SARHITLHDPRVGASSKVTQQQLIGHKNFVSSLDTCPENEYILCSGSHDGTVKVWD 404 >5OQL-X nrPDB Length = 630 Score = 50.9 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 34/196 (17%), Positives = 63/196 (32%), Gaps = 16/196 (8%) Query: 159 VVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDL 217 VV + D + TGG D + V+ L+ + F H + LA + + +D Sbjct: 251 VVKASQDGKFVVTGGADKRLVVYNAADLKPIKAFTQHRDAVTGLAFRRGTNQLYSCSKDR 310 Query: 218 KASVWQKDQLVTQL----HWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTV-QIPHK 272 VW D+L H E + R C V + R + V + Sbjct: 311 TVKVWSLDELAYVETLFGHQDEILDIDALGQER---C--VSVGARDRTARYWKVPEESQL 365 Query: 273 RLRQPPPCYLTAWDGSNFLPL---RTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIA 329 R + P + + + + + G+ G +A++ Sbjct: 366 VFRGGGEGGSSNTKKHKLPPGMDPASAAHEGSMDRVAMIDDD--MFVTGSDNGDLALWSI 423 Query: 330 FSLQCLYYVREAHGIV 345 + L+ + AHG+ Sbjct: 424 QRKKPLHVIARAHGLE 439 Score = 31.2 bits (69), Expect = 0.92, Method: Composition-based stats. Identities = 9/26 (34%), Positives = 17/26 (65%) Query: 166 NTLLATGGTDGYVRVWKVPSLEKVLE 191 + L+ +G DG +RVW++ ++ LE Sbjct: 475 SDLIFSGSWDGCIRVWRLSEDKRKLE 500 >5K0Y-T nrPDB Length = 329 Score = 50.5 bits (119), Expect = 1e-06, Method: Composition-based stats. Identities = 38/214 (17%), Positives = 65/214 (30%), Gaps = 21/214 (9%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK-LVTVGRDLKAS 220 +N + LL T D V VW + E++ + H G + + D K ++T D Sbjct: 18 YNREGDLLFTVAKDPIVNVWYSVNGERLGTYMGHTGAVWCVDADWDTKHVLTGSADNSCR 77 Query: 221 VWQ--KDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGL--RLFTVQIPHKRLRQ 276 +W + + L T + F F ++ P + Sbjct: 78 LWDCETGKQLALLKTNSAVRT-CGFDFGGNIIMFSTDKQMGYQCFVSFFDLRDPSQI--- 133 Query: 277 PPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLY 336 N P C ++ G + G +G + Y A S + L Sbjct: 134 -----------DNNEPYMKIPCNDSKITSAVWGPLGECIIAGHESGELNQYSAKSGEVLV 182 Query: 337 YVREAHGIVVTDVAFLPEKGRGPELLGSHETALF 370 V+E H + D+ E + LF Sbjct: 183 NVKE-HSRQINDIQLSREMTMFVTASKDNTAKLF 215 Score = 39.7 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 18/89 (20%), Positives = 32/89 (35%), Gaps = 15/89 (16%) Query: 148 QTDFSSDPLQKVVCFNHDNTLLATGGTDG--------------YVRVWKVPSLEKVLEFK 193 Q F ++P +++ + + + GG R + + E+ K Sbjct: 223 QKTFRTEPPRELAALSPNYEHVVVGGGQEAMDVTTTSTRIGKFEARFFHLAFEEEFGRVK 282 Query: 194 AHEGEIEDLALGPDGK-LVTVGRDLKASV 221 H G I +A PDGK + G D + Sbjct: 283 GHFGPINSVAFHPDGKSYSSGGEDGYVRI 311 >5WJC-A nrPDB Length = 430 Score = 49.7 bits (117), Expect = 2e-06, Method: Composition-based stats. Identities = 23/116 (19%), Positives = 45/116 (38%), Gaps = 5/116 (4%) Query: 115 PRQRKGAAPAEKKCGAETQHEGLELRVENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGT 174 P+ A C + L E + +Q S + V ++ LLAT Sbjct: 245 PQHEALLASVSDDCTLQIHDTRLNPEEEAPKVIQA--HSKAINAVAINPFNDYLLATASA 302 Query: 175 DGYVRVWKVPS-LEKVLEFKAHEGEIEDLALGPDGK--LVTVGRDLKASVWQKDQL 227 D V +W + + +++ + HE E+ L P + L + D + +W +++ Sbjct: 303 DKTVALWDLRNPYQRLHTLEGHEDEVYGLEWSPHDEPILASSSTDRRVCIWDLEKI 358 Score = 42.4 bits (98), Expect = 3e-04, Method: Composition-based stats. Identities = 15/81 (18%), Positives = 29/81 (35%), Gaps = 16/81 (19%) Query: 164 HDNTLLATGGTDGYVRVWKVPSL--------------EKVLEFKAHEGEIEDLALGPDGK 209 HD +LA+ TD V +W + + E + H I + + P+ + Sbjct: 336 HDEPILASSSTDRRVCIWDLEKIGEEQTPEDAEDGSPELLFMHGGHTNRISEFSWCPNER 395 Query: 210 LVTVG--RDLKASVWQKDQLV 228 V D +W +++ Sbjct: 396 WVVGSLADDNILQIWSPSRVI 416 Score = 40.5 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 30/212 (14%), Positives = 55/212 (25%), Gaps = 44/212 (20%) Query: 167 TLLATGGTDGYVRVWKVPSLEKVLE--------FKAHEGEIEDLALGPD--GKLVTVGRD 216 ++AT G G ++ + + K H E L P+ G L T D Sbjct: 145 EIIATMGEGGNAYIFDTTCHDALTTGEALPQAVLKGHTAEGFGLCWNPNLPGNLATGAED 204 Query: 217 LKASVWQ-KDQLVTQ------------LHWQENGPTFSSTPYRYQACRFGQVPDQPAGLR 263 +W + Q T + P Q L+ Sbjct: 205 QVICLWDVQTQSFTSSETKVISPIAKYHRHTDIVNDVQFHP---QHEALLASVSDDCTLQ 261 Query: 264 LFTVQ-IPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTG 322 + + P + + + A + P D L + Sbjct: 262 IHDTRLNPEEEAPKVIQAHSKAINAVAINPFN------------DY-----LLATASADK 304 Query: 323 SVAIYIAFSLQCLYYVREAHGIVVTDVAFLPE 354 +VA++ + + E H V + + P Sbjct: 305 TVALWDLRNPYQRLHTLEGHEDEVYGLEWSPH 336 >5OV3-A nrPDB Length = 381 Score = 48.6 bits (114), Expect = 5e-06, Method: Composition-based stats. Identities = 21/63 (33%), Positives = 26/63 (41%), Gaps = 1/63 (1%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDG-KLVTVGRDLKAS 220 FN TLLA G DG + +W + AH + L DG KLV+ D S Sbjct: 33 FNRWGTLLAVGCNDGRIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDNIVS 92 Query: 221 VWQ 223 W Sbjct: 93 QWD 95 Score = 30.9 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 10/34 (29%), Positives = 16/34 (47%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFK 193 +C++ D L + TD V W V S + F+ Sbjct: 73 LCWSRDGHKLVSASTDNIVSQWDVLSGDCDQRFR 106 >3C9C-A nrPDB Length = 432 Score = 48.6 bits (114), Expect = 5e-06, Method: Composition-based stats. Identities = 15/89 (16%), Positives = 31/89 (34%), Gaps = 9/89 (10%) Query: 167 TLLATGGTDGYVRVWKVPSLEKVL---EFKAHEGEIEDLALGPDGKLV--TVGRDLKASV 221 +L + D + +W + AH E+ L+ P + + T D ++ Sbjct: 247 SLFGSVADDQKLMIWDTRNNNTSKPSHTVDAHTAEVNCLSFNPYSEFILATGSADKTVAL 306 Query: 222 WQKDQLVTQLHW----QENGPTFSSTPYR 246 W L +LH ++ +P+ Sbjct: 307 WDLRNLKLKLHSFESHKDEIFQVQWSPHN 335 Score = 47.8 bits (112), Expect = 8e-06, Method: Composition-based stats. Identities = 22/76 (28%), Positives = 39/76 (51%), Gaps = 6/76 (7%) Query: 158 KVVC--FNHDNT-LLATGGTDGYVRVWKVPSLEK-VLEFKAHEGEIEDLALGPDGK--LV 211 +V C FN + +LATG D V +W + +L+ + F++H+ EI + P + L Sbjct: 281 EVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILA 340 Query: 212 TVGRDLKASVWQKDQL 227 + G D + VW ++ Sbjct: 341 SSGTDRRLHVWDLSKI 356 Score = 47.4 bits (111), Expect = 1e-05, Method: Composition-based stats. Identities = 32/179 (17%), Positives = 63/179 (35%), Gaps = 21/179 (11%) Query: 184 PSLEKV--LEFKAHEGEIEDLALGPD--GKLVTVGRDLKASVWQKDQLVTQLHWQENGPT 239 PS E L + H+ E L+ P+ G L++ D +W + + + Sbjct: 169 PSGECQPDLRLRGHQKEGYGLSWNPNLNGYLLSASDDHTICLWDINATPKEHRVIDAKNI 228 Query: 240 FSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWD---GSNFLPLRTK 296 F+ + + + + LF ++ L WD + P T Sbjct: 229 FTGHTAVVEDVAWHLLHES-----LFGSVADDQK--------LMIWDTRNNNTSKPSHTV 275 Query: 297 SCGHEVVSCLDVSESGTFL-GLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPE 354 V+CL + F+ G+ +VA++ +L+ + E+H + V + P Sbjct: 276 DAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPH 334 Score = 42.4 bits (98), Expect = 3e-04, Method: Composition-based stats. Identities = 25/119 (21%), Positives = 44/119 (36%), Gaps = 19/119 (15%) Query: 141 VENLQAVQTDFSS--DPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSL------------ 186 + NL+ F S D + +V H+ T+LA+ GTD + VW + + Sbjct: 309 LRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLHVWDLSKIGEEQSTEDAEDG 368 Query: 187 --EKVLEFKAHEGEIEDLALGPDGK--LVTVGRDLKASVWQ-KDQLVTQLHWQENGPTF 240 E + H +I D + P+ + +V D VWQ + + + Sbjct: 369 PPELLFIHGGHTAKISDFSWNPNEPWIICSVSEDNIMQVWQMAENVYNDEEPEIPASEL 427 >5BJS-A nrPDB Length = 605 Score = 48.6 bits (114), Expect = 5e-06, Method: Composition-based stats. Identities = 20/74 (27%), Positives = 29/74 (39%), Gaps = 9/74 (12%) Query: 151 FSSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKL 210 +S DP+ D LL G +G V+V+ V + H G I DLA P Sbjct: 140 WSKDPIT-------DQPLLCIAGNEGNVKVYNVTEGKLYRTLVGHGGGINDLATSPANPY 192 Query: 211 V--TVGRDLKASVW 222 + + D +W Sbjct: 193 IIASASDDTTIRIW 206 Score = 41.3 bits (95), Expect = 9e-04, Method: Composition-based stats. Identities = 12/83 (14%), Positives = 33/83 (39%), Gaps = 7/83 (8%) Query: 156 LQKVVCFNHDNTLLATGGTDGYVRVWKVP------SLEKVLEFKAHEGEIEDLALGPDGK 209 + + + ++A+ D +R+W + +L + H ++ +A +G+ Sbjct: 181 INDLATSPANPYIIASASDDTTIRIWSLAPEHEKQPCVCILGGEGHSYDLLSVAFHDNGR 240 Query: 210 LV-TVGRDLKASVWQKDQLVTQL 231 V + G D ++W + + Sbjct: 241 YVLSAGHDQVINLWALPEFPNEH 263 Score = 30.5 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 27/131 (20%), Positives = 39/131 (29%), Gaps = 30/131 (22%) Query: 293 LRTKSCGHEVVSCL--DVSESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVA 350 +R SC D L + G+V +Y + LY HG + D+A Sbjct: 127 IRDDGNEANCASCWSKDPITDQPLLCIAGNEGNVKVYNVTEGK-LYRTLVGHGGGINDLA 185 Query: 351 FLP------------------------EKGRGPELLGS--HETALFSVAVDSRCQLHLL- 383 P EK +LG H L SVA + L Sbjct: 186 TSPANPYIIASASDDTTIRIWSLAPEHEKQPCVCILGGEGHSYDLLSVAFHDNGRYVLSA 245 Query: 384 PSRRSVPVWLL 394 + + +W L Sbjct: 246 GHDQVINLWAL 256 >5WBU-D nrPDB Length = 328 Score = 48.6 bits (114), Expect = 5e-06, Method: Composition-based stats. Identities = 17/70 (24%), Positives = 28/70 (40%), Gaps = 9/70 (12%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGE--------IEDLALGPDGKLV-T 212 F+ D+TLLAT D ++W+ + + E G + A D + + T Sbjct: 230 FSPDSTLLATCSADQTCKIWRTSNFSLMTELSIKSGNPGESSRGWMWGCAFSGDSQYIVT 289 Query: 213 VGRDLKASVW 222 D A +W Sbjct: 290 ASSDNLARLW 299 Score = 48.2 bits (113), Expect = 7e-06, Method: Composition-based stats. Identities = 26/167 (15%), Positives = 43/167 (25%), Gaps = 52/167 (31%) Query: 165 DNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV------------- 211 D +LAT G D VR W+ S + + ++ L + PD ++ Sbjct: 13 DPVILATAGYDHTVRFWQAHSGICTRTVQHQDSQVNALEVTPDRSMIAAAGYQHIRMYDL 72 Query: 212 -------------------------------TVGRDLKASVWQKD----QLVTQLHWQEN 236 T G D A +W Q Sbjct: 73 NSNNPNPIISYDGVNKNIASVGFHEDGRWMYTGGEDCTARIWDLRSRNLQCQRIFQVNAP 132 Query: 237 GPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLT 283 P + + V DQ + ++ ++ H P P Sbjct: 133 INCVCLHPNQAEL----IVGDQSGAIHIWDLKTDHNEQLIPEPEVSI 175 Score = 46.6 bits (109), Expect = 2e-05, Method: Composition-based stats. Identities = 32/242 (13%), Positives = 66/242 (27%), Gaps = 48/242 (19%) Query: 162 FNHDNTLLATGGTDGYVRVWKV--PSLEKVLEFKAHEGEIEDLALGPD-GKLVTVGRDLK 218 F+ D + TGG D R+W + +L+ F+ I + L P+ +L+ + Sbjct: 95 FHEDGRWMYTGGEDCTARIWDLRSRNLQCQRIFQV-NAPINCVCLHPNQAELIVGDQSGA 153 Query: 219 ASVWQKDQLVTQLHWQENGPTFSST---PYRYQACRFGQVPDQPAGLRLFTVQ--IPHKR 273 +W + E + +S P + ++ + I + Sbjct: 154 IHIWDLKTDHNEQLIPEPEVSITSAHIDPDASYMAAVNSTGN----CYVWNLTGGIGDEV 209 Query: 274 LRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIY--IAFS 331 + P + A S T L + + I+ FS Sbjct: 210 TQLIPKTKIPAHTRYALQC--------------RFSPDSTLLATCSADQTCKIWRTSNFS 255 Query: 332 LQCLYYVREAHGIVVTDVAFLPEKGRGPELLGSHETALFSVAVDSRCQLHLLPSR-RSVP 390 L ++ + + ++ A Q + S Sbjct: 256 LMTELSIKSGNPGESSR------------------GWMWGCAFSGDSQYIVTASSDNLAR 297 Query: 391 VW 392 +W Sbjct: 298 LW 299 Score = 44.3 bits (103), Expect = 9e-05, Method: Composition-based stats. Identities = 12/44 (27%), Positives = 21/44 (47%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALG 205 F+ D+ + T +D R+W V + E E+ H+ + LA Sbjct: 280 FSGDSQYIVTASSDNLARLWCVETGEIKREYGGHQKAVVCLAFN 323 Score = 42.4 bits (98), Expect = 3e-04, Method: Composition-based stats. Identities = 35/217 (16%), Positives = 60/217 (27%), Gaps = 10/217 (4%) Query: 138 ELRVENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEG 197 +LR NLQ + + P+ VC + + L G G + +W + + E Sbjct: 115 DLRSRNLQCQRIFQVNAPIN-CVCLHPNQAELIVGDQSGAIHIWDLKTDHNEQLIPEPEV 173 Query: 198 EIEDLALGPDGKLVTV-GRDLKASVWQKDQLVTQLHWQENGPTFSSTPYRYQA-CRFGQV 255 I + PD + VW + Q T RY CRF Sbjct: 174 SITSAHIDPDASYMAAVNSTGNCYVWNLTGGIGDEVTQLIPKTKIPAHTRYALQCRFSPD 233 Query: 256 PDQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFL 315 A + L+ G+ R G S ++ Sbjct: 234 STLLATCSADQTCKIWRTSNFSLMTELSIKSGNPGESSRGWMWGC------AFSGDSQYI 287 Query: 316 GLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFL 352 + ++ + + + H V +AF Sbjct: 288 VTASSDNLARLWCVETGE-IKREYGGHQKAVVCLAFN 323 >3BG0-A nrPDB Length = 316 Score = 48.6 bits (114), Expect = 5e-06, Method: Composition-based stats. Identities = 23/139 (16%), Positives = 48/139 (34%), Gaps = 18/139 (12%) Query: 163 NHDNTLLATGGTDGYVRVWKVPSLE--KVLEFKAHEGEIEDLALGPD--GK-LVTVGRDL 217 ++ T LAT +D V+++ V + + + + HEG + +A G L + D Sbjct: 22 DYYGTRLATCSSDRSVKIFDVRNGGQILIADLRGHEGPVWQVAWAHPMYGNILASCSYDR 81 Query: 218 KASVWQKDQLV---TQLHW--QENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTV----- 267 K +W+++ + H + + P+ Y + L T Sbjct: 82 KVIIWREENGTWEKSHEHAGHDSSVNSVCWAPHDYGL--ILACGSSDGAISLLTYTGEGQ 139 Query: 268 -QIPHKRLRQPPPCYLTAW 285 ++ C +W Sbjct: 140 WEVKKINNAHTIGCNAVSW 158 Score = 38.9 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 14/69 (20%), Positives = 30/69 (43%), Gaps = 8/69 (11%) Query: 169 LATGGTDGYVRVWKVP---SLEKVLEFKAHEGEIEDLALGPD-----GKLVTVGRDLKAS 220 A+GG D +++WK ++ + +AH + D+A P + + +D + Sbjct: 182 FASGGCDNLIKLWKEEEDGQWKEEQKLEAHSDWVRDVAWAPSIGLPTSTIASCSQDGRVF 241 Query: 221 VWQKDQLVT 229 +W D + Sbjct: 242 IWTCDDASS 250 Score = 29.7 bits (65), Expect = 2.4, Method: Composition-based stats. Identities = 12/67 (17%), Positives = 26/67 (38%), Gaps = 11/67 (16%) Query: 166 NTLLATGGTDGYVRVW-------KVPSLEKVLEFKAHEGEIEDLALGPDGK-LVTVGRDL 217 + +A+ DG V +W S + + +F + ++ L G D Sbjct: 228 TSTIASCSQDGRVFIWTCDDASSNTWSPKLLHKF---NDVVWHVSWSITANILAVSGGDN 284 Query: 218 KASVWQK 224 K ++W++ Sbjct: 285 KVTLWKE 291 >3CFV-B nrPDB Length = 414 Score = 48.6 bits (114), Expect = 5e-06, Method: Composition-based stats. Identities = 22/84 (26%), Positives = 43/84 (51%), Gaps = 6/84 (7%) Query: 158 KVVC--FNHDNT-LLATGGTDGYVRVWKVPSLEK-VLEFKAHEGEIEDLALGPDGK--LV 211 +V C FN + +LATG D V +W + +L+ + F++H+ EI + P + L Sbjct: 277 EVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSPHNETILA 336 Query: 212 TVGRDLKASVWQKDQLVTQLHWQE 235 + G D + +VW ++ + ++ Sbjct: 337 SSGTDRRLNVWDLSKIGEEQSAED 360 Score = 46.6 bits (109), Expect = 2e-05, Method: Composition-based stats. Identities = 16/89 (17%), Positives = 31/89 (34%), Gaps = 9/89 (10%) Query: 167 TLLATGGTDGYVRVWKVPSLEKVLE---FKAHEGEIEDLALGPDGKLV--TVGRDLKASV 221 +L + D + +W S AH E+ L+ P + + T D ++ Sbjct: 243 SLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVAL 302 Query: 222 WQKDQLVTQLHW----QENGPTFSSTPYR 246 W L +LH ++ +P+ Sbjct: 303 WDLRNLKLKLHTFESHKDEIFQVHWSPHN 331 Score = 41.6 bits (96), Expect = 6e-04, Method: Composition-based stats. Identities = 18/85 (21%), Positives = 33/85 (38%), Gaps = 17/85 (20%) Query: 164 HDNTLLATGGTDGYVRVWKVPSL--------------EKVLEFKAHEGEIEDLALGPDGK 209 H+ T+LA+ GTD + VW + + E + H +I D + P+ Sbjct: 330 HNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEP 389 Query: 210 --LVTVGRDLKASVWQ-KDQLVTQL 231 + +V D +WQ + + Sbjct: 390 WVICSVSEDNIMQIWQMAENIYNDE 414 Score = 39.7 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 41/244 (16%), Positives = 81/244 (33%), Gaps = 33/244 (13%) Query: 120 GAAPAEKKCGAETQHEGLELRVENL-QAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYV 178 G+ + +C + HEG R + Q + P V+ F++ D Sbjct: 111 GSVTGKIECEIKINHEGEVNRARYMPQNPHIIATKTPSSDVLVFDYTKH---PAKPD--- 164 Query: 179 RVWKVPSLEKV--LEFKAHEGEIEDLALGPD--GKLVTVGRDLKASVWQKDQLVTQLHWQ 234 PS E L + H+ E L+ + G L++ D +W + + Sbjct: 165 -----PSGECNPDLRLRGHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIV 219 Query: 235 ENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWD---GSNFL 291 + F+ + + + + LF ++ L WD + Sbjct: 220 DAKAIFTGHSAVVEDVAWHLLHES-----LFGSVADDQK--------LMIWDTRSNTTSK 266 Query: 292 PLRTKSCGHEVVSCLDVSESGTFL-GLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVA 350 P V+CL + F+ G+ +VA++ +L+ + E+H + V Sbjct: 267 PSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVH 326 Query: 351 FLPE 354 + P Sbjct: 327 WSPH 330 >4XYI-A nrPDB Length = 430 Score = 48.2 bits (113), Expect = 6e-06, Method: Composition-based stats. Identities = 23/77 (29%), Positives = 37/77 (48%), Gaps = 5/77 (6%) Query: 155 PLQKVVCFNHDNT-LLATGGTDGYVRVWKVPSL-EKVLEFKAHEGEIEDLALGPDGK--L 210 P+ V FN N LLAT D V +W + L +++ + HE E+ ++ P + L Sbjct: 283 PVNGV-AFNPFNDYLLATASADHTVALWDLRRLNQRLHTLEGHEDEVYNVQWSPHDEPIL 341 Query: 211 VTVGRDLKASVWQKDQL 227 VT D + VW ++ Sbjct: 342 VTSSTDRRVCVWDLSKI 358 Score = 44.3 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 23/107 (21%), Positives = 40/107 (37%), Gaps = 16/107 (14%) Query: 138 ELRVENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSL----------- 186 +LR N + + D + V HD +L T TD V VW + + Sbjct: 310 DLRRLNQRLHTLEGHEDEVYNVQWSPHDEPILVTSSTDRRVCVWDLSKIGEEQTVEDSED 369 Query: 187 ---EKVLEFKAHEGEIEDLALGPDGK--LVTVGRDLKASVWQKDQLV 228 E + H + DL+ P+ K L ++ D +W +++ Sbjct: 370 GAPELMFMHGGHTNRVSDLSWNPNNKWVLASLADDNILQIWSPSKVI 416 Score = 36.6 bits (83), Expect = 0.020, Method: Composition-based stats. Identities = 18/70 (25%), Positives = 28/70 (40%), Gaps = 5/70 (7%) Query: 168 LLATGGTDGYVRVWKV---PSLEKVLEFKAHEGEIEDLALGP--DGKLVTVGRDLKASVW 222 LL + D +++ S KAHE + +A P D L T D ++W Sbjct: 250 LLTSVSDDCTLQIHDTRLPSSSSASQCVKAHEQPVNGVAFNPFNDYLLATASADHTVALW 309 Query: 223 QKDQLVTQLH 232 +L +LH Sbjct: 310 DLRRLNQRLH 319 >5WYJ-BE nrPDB Length = 939 Score = 48.2 bits (113), Expect = 7e-06, Method: Composition-based stats. Identities = 13/89 (14%), Positives = 27/89 (30%), Gaps = 3/89 (3%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK-LVTVGRDLK 218 + ++ + L A D + V + V + H I P+G+ +V+ D Sbjct: 549 MVYHRSSDLFALALDDLSIVVIDAVTQRVVRQLWGHSNRITAFDFSPEGRWIVSASLDST 608 Query: 219 ASVWQK--DQLVTQLHWQENGPTFSSTPY 245 W + + +P Sbjct: 609 IRTWDLPTGGCIDGIIVDNVATNVKFSPN 637 Score = 33.5 bits (75), Expect = 0.18, Method: Composition-based stats. Identities = 11/67 (16%), Positives = 23/67 (34%), Gaps = 2/67 (2%) Query: 167 TLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK--LVTVGRDLKASVWQK 224 ++A G G V ++ + +++ K + I L+ DG L + Sbjct: 219 DIIALGTVTGEVIMFNMRKGKRIRTIKIPQSRISSLSFRTDGSSHLSVGTSSGDLIFYDL 278 Query: 225 DQLVTQL 231 D+ Sbjct: 279 DRRSRIH 285 >6CHG-A nrPDB Length = 312 Score = 48.2 bits (113), Expect = 7e-06, Method: Composition-based stats. Identities = 30/230 (13%), Positives = 64/230 (27%), Gaps = 22/230 (9%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK-LVTVGRDLK 218 +C++ D+ +A+G D V + + + H + + G L + D Sbjct: 60 LCWSPDSKCIASGSEDFTVEITHIIYGR-IRRLMGHTAPVISICYNNKGNILCSSSMDES 118 Query: 219 ASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPP 278 W + S +R+F + H Sbjct: 119 IKEWHVLSGTALKTMSAHSDAVVSIDIPKFDSSILSSGSYDGLIRIFDTESGHCLKTLTY 178 Query: 279 PCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYV 338 A DG +S + S +G FL + ++ V ++ + Sbjct: 179 DKDWIAEDGV------------VPISTVKFSRNGKFLLVKSLDNVVKLWEYTRGTVVRTF 226 Query: 339 REAHGIVVTDVAFL-------PEKGRGPELLGSHETALFSVAVDSRCQLH 381 H + + P+ G+ P ++ +++ V L Sbjct: 227 LWPHQETKAKLKYNCGLELIYPQ-GKDPLVISGNDSGSMCVWNVYSKNLV 275 Score = 45.9 bits (107), Expect = 3e-05, Method: Composition-based stats. Identities = 26/180 (14%), Positives = 55/180 (30%), Gaps = 29/180 (16%) Query: 163 NHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK-LVTVGRDLKASV 221 + D L+A + V+++ S + + H+ I L PD K + + D + Sbjct: 22 SPDGELIAICQNTDML-VYEISSSKMMKLTTTHKECINCLCWSPDSKCIASGSEDFTVEI 80 Query: 222 WQK--DQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPP 279 ++ + + C ++ Sbjct: 81 THIIYGRIRRLMGHTAPVISICYNNKGNILCS----SSMDESIK---------------- 120 Query: 280 CYLTAWDGSNFLPLRTKSCGHEVVSCLDVSE-SGTFLGLGTVTGSVAIYIAFSLQCLYYV 338 W + L+T S + V +D+ + + L G+ G + I+ S CL + Sbjct: 121 ----EWHVLSGTALKTMSAHSDAVVSIDIPKFDSSILSSGSYDGLIRIFDTESGHCLKTL 176 Score = 44.7 bits (104), Expect = 7e-05, Method: Composition-based stats. Identities = 17/83 (20%), Positives = 35/83 (42%), Gaps = 9/83 (10%) Query: 153 SDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFK------AHEG--EIEDLAL 204 SD + + D+++L++G DG +R++ S + A +G I + Sbjct: 137 SDAVVSIDIPKFDSSILSSGSYDGLIRIFDTESGHCLKTLTYDKDWIAEDGVVPISTVKF 196 Query: 205 GPDGKLVTVGR-DLKASVWQKDQ 226 +GK + V D +W+ + Sbjct: 197 SRNGKFLLVKSLDNVVKLWEYTR 219 Score = 44.7 bits (104), Expect = 8e-05, Method: Composition-based stats. Identities = 28/198 (14%), Positives = 65/198 (32%), Gaps = 31/198 (15%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGP-DGKLVTVGR-DL 217 +C+N+ +L + D ++ W V S + AH + + + D +++ G D Sbjct: 101 ICYNNKGNILCSSSMDESIKEWHVLSGTALKTMSAHSDAVVSIDIPKFDSSILSSGSYDG 160 Query: 218 KASVWQKD--QLVTQLHWQE---------NGPTFSSTPYRYQACRFGQVPDQPAGLRLFT 266 ++ + + L + + T + +F V ++L+ Sbjct: 161 LIRIFDTESGHCLKTLTYDKDWIAEDGVVPISTVKFSRNG----KFLLVKSLDNVVKLWE 216 Query: 267 VQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGT--FLGLGTVTGSV 324 + W +CG E++ G + G +GS+ Sbjct: 217 YT-------RGTVVRTFLWPHQETKAKLKYNCGLELI-----YPQGKDPLVISGNDSGSM 264 Query: 325 AIYIAFSLQCLYYVREAH 342 ++ +S + + E H Sbjct: 265 CVWNVYSKNLVQKIDEKH 282 Score = 28.5 bits (62), Expect = 5.1, Method: Composition-based stats. Identities = 12/64 (18%), Positives = 27/64 (42%), Gaps = 6/64 (9%) Query: 333 QCLYYVREAHGIVVTDVAFLPEKGRGPELLGSHETALFSVAVDSRCQLHLLPSRR-SVPV 391 +C+ E + +T + + GR L+ H + S+ +++ + S S+ Sbjct: 67 KCIASGSEDFTVEITHIIY----GRIRRLM-GHTAPVISICYNNKGNILCSSSMDESIKE 121 Query: 392 WLLL 395 W +L Sbjct: 122 WHVL 125 >5Y1U-A nrPDB Length = 456 Score = 48.2 bits (113), Expect = 7e-06, Method: Composition-based stats. Identities = 22/76 (28%), Positives = 40/76 (52%), Gaps = 6/76 (7%) Query: 158 KVVC--FNHDNT-LLATGGTDGYVRVWKVPSLEK-VLEFKAHEGEIEDLALGPDGK--LV 211 +V C FN + +LATG D V +W + +L+ + F++H+ EI + P + L Sbjct: 306 EVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILA 365 Query: 212 TVGRDLKASVWQKDQL 227 + G D + +VW ++ Sbjct: 366 SSGTDRRLNVWDLSKI 381 Score = 47.4 bits (111), Expect = 1e-05, Method: Composition-based stats. Identities = 16/89 (17%), Positives = 31/89 (34%), Gaps = 9/89 (10%) Query: 167 TLLATGGTDGYVRVWKVPSLEKVL---EFKAHEGEIEDLALGPDGKLV--TVGRDLKASV 221 +L + D + +W S AH E+ L+ P + + T D ++ Sbjct: 272 SLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVAL 331 Query: 222 WQKDQLVTQLHW----QENGPTFSSTPYR 246 W L +LH ++ +P+ Sbjct: 332 WDLRNLKLKLHSFESHKDEIFQVQWSPHN 360 Score = 41.6 bits (96), Expect = 6e-04, Method: Composition-based stats. Identities = 25/110 (22%), Positives = 43/110 (39%), Gaps = 19/110 (17%) Query: 141 VENLQAVQTDFSS--DPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSL------------ 186 + NL+ F S D + +V H+ T+LA+ GTD + VW + + Sbjct: 334 LRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDG 393 Query: 187 --EKVLEFKAHEGEIEDLALGPDGK--LVTVGRDLKASVWQ-KDQLVTQL 231 E + H +I D + P+ + +V D VWQ + + Sbjct: 394 PPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDE 443 Score = 41.3 bits (95), Expect = 8e-04, Method: Composition-based stats. Identities = 31/179 (17%), Positives = 63/179 (35%), Gaps = 21/179 (11%) Query: 184 PSLEKV--LEFKAHEGEIEDLALGPD--GKLVTVGRDLKASVWQKDQLVTQLHWQENGPT 239 PS E L + H+ E L+ P+ G L++ D +W + + + Sbjct: 194 PSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTI 253 Query: 240 FSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWD---GSNFLPLRTK 296 F+ + + + + LF ++ L WD + P + Sbjct: 254 FTGHTAVVEDVSWHLLHES-----LFGSVADDQK--------LMIWDTRSNNTSKPSHSV 300 Query: 297 SCGHEVVSCLDVSESGTFL-GLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPE 354 V+CL + F+ G+ +VA++ +L+ + E+H + V + P Sbjct: 301 DAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPH 359 >1NR0-A nrPDB Length = 611 Score = 47.8 bits (112), Expect = 8e-06, Method: Composition-based stats. Identities = 19/70 (27%), Positives = 30/70 (42%), Gaps = 8/70 (11%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFK-------AHEGEIEDLALGPDG-KLVTV 213 +N D +L A+ G DG + ++ K F+ AH G + L PDG K+ + Sbjct: 198 YNPDGSLFASTGGDGTIVLYNGVDGTKTGVFEDDSLKNVAHSGSVFGLTWSPDGTKIASA 257 Query: 214 GRDLKASVWQ 223 D +W Sbjct: 258 SADKTIKIWN 267 Score = 42.4 bits (98), Expect = 3e-04, Method: Composition-based stats. Identities = 30/199 (15%), Positives = 62/199 (31%), Gaps = 21/199 (10%) Query: 156 LQKVVCFNHDNTL-LATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKL-VTV 213 + V F + +G D V +++ P + F H + + PDG L + Sbjct: 150 MNSVD-FKPSRPFRIISGSDDNTVAIFEGPPFKFKSTFGEHTKFVHSVRYNPDGSLFAST 208 Query: 214 GRDLKASVWQ-KDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHK 272 G D ++ D T + ++ + + FG K Sbjct: 209 GGDGTIVLYNGVDGTKTGVFEDDSLKNVAHS-----GSVFGLTWSPDGT----------K 253 Query: 273 RLRQPPPCYLTAWDGSNFLPLRTKSCGHEV-VSCLDVSESGTFLGLGTVTGSVAIYIAFS 331 + W+ + +T G + L + + L + G + ++ Sbjct: 254 IASASADKTIKIWNVATLKVEKTIPVGTRIEDQQLGIIWTKQALVSISANGFIN-FVNPE 312 Query: 332 LQCLYYVREAHGIVVTDVA 350 L + VR H +T ++ Sbjct: 313 LGSIDQVRYGHNKAITALS 331 Score = 36.6 bits (83), Expect = 0.018, Method: Composition-based stats. Identities = 15/91 (16%), Positives = 32/91 (35%), Gaps = 10/91 (10%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPS---LEKVLEFKAHEGEIEDLALGPDG-KLVTVGR 215 V F+++ L V + V + L + H ++ ++ PD +L T Sbjct: 497 VAFSNNGAFLVATDQSRKVIPYSVANNFELAHTNSWTFHTAKVACVSWSPDNVRLATGSL 556 Query: 216 DLKASVWQKDQ------LVTQLHWQENGPTF 240 D VW ++ ++ H + + Sbjct: 557 DNSVIVWNMNKPSDHPIIIKGAHAMSSVNSV 587 Score = 35.5 bits (80), Expect = 0.048, Method: Composition-based stats. Identities = 41/274 (14%), Positives = 78/274 (28%), Gaps = 75/274 (27%) Query: 151 FSSDPLQKV--------VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEF---------- 192 F D L+ V + ++ D T +A+ D +++W V +L+ Sbjct: 228 FEDDSLKNVAHSGSVFGLTWSPDGTKIASASADKTIKIWNVATLKVEKTIPVGTRIEDQQ 287 Query: 193 ---------------------------------KAHEGEIEDLALGPDGK-LVTVGRDLK 218 H I L+ DGK L + + Sbjct: 288 LGIIWTKQALVSISANGFINFVNPELGSIDQVRYGHNKAITALSSSADGKTLFSADAEGH 347 Query: 219 ASVWQ-----KDQLVTQLHWQENGPTFSSTPYRY----QACRFGQVPDQPAGLRLFTVQI 269 + W +++ +H +++ VP +G+ + + Sbjct: 348 INSWDISTGISNRVFPDVHATMITGIKTTSKGDLFTVSWDDHLKVVPAGGSGVD--SSKA 405 Query: 270 PHKRLRQPPPCYLTAWDGS-------NFLPLRTKSCGHEV-----VSCLDVSESGTFLGL 317 +L P + DG + + + EV SC+ +S F+ + Sbjct: 406 VANKLSSQPLGLAVSADGDIAVAACYKHIAIYSHGKLTEVPISYNSSCVALSNDKQFVAV 465 Query: 318 GTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAF 351 G V +Y H +T VAF Sbjct: 466 GGQDSKVHVYKLSGASVSEVKTIVHPAEITSVAF 499 Score = 35.1 bits (79), Expect = 0.058, Method: Composition-based stats. Identities = 23/86 (26%), Positives = 37/86 (43%), Gaps = 5/86 (5%) Query: 143 NLQAVQTDFSSDPLQKVVC--FNHDNTLLATGGTDGYVRVWKV--PSLEKVLEFKAHE-G 197 N + T+ + KV C ++ DN LATG D V VW + PS ++ AH Sbjct: 523 NFELAHTNSWTFHTAKVACVSWSPDNVRLATGSLDNSVIVWNMNKPSDHPIIIKGAHAMS 582 Query: 198 EIEDLALGPDGKLVTVGRDLKASVWQ 223 + + + +V+ G+D W Sbjct: 583 SVNSVIWLNETTIVSAGQDSNIKFWN 608 >2AQ5-A nrPDB Length = 402 Score = 47.4 bits (111), Expect = 1e-05, Method: Composition-based stats. Identities = 18/80 (22%), Positives = 34/80 (42%), Gaps = 9/80 (11%) Query: 155 PLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEK-------VLEFKAHEGEIEDLALGPD 207 P+ + H++ ++A+G D V VW++P V+ + H + +A P Sbjct: 83 PVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLVLPLREPVITLEGHTKRVGIVAWHPT 142 Query: 208 GK--LVTVGRDLKASVWQKD 225 + L++ G D VW Sbjct: 143 AQNVLLSAGCDNVILVWDVG 162 >6BX3-B nrPDB Length = 412 Score = 47.0 bits (110), Expect = 1e-05, Method: Composition-based stats. Identities = 19/79 (24%), Positives = 36/79 (45%), Gaps = 6/79 (7%) Query: 154 DPLQ-KVVCFNHDNTLLATGGTDGYVRVWKVPSLEKV----LEFKAHEGEIEDLALGPDG 208 +PL+ + + F+ LA G +G + ++ + + + AH I +A PDG Sbjct: 24 NPLRTECLQFSPCGDYLALGCANGALVIYDMDTFRPICVPGNMLGAHVRPITSIAWSPDG 83 Query: 209 K-LVTVGRDLKASVWQKDQ 226 + L+T RD +W + Sbjct: 84 RLLLTSSRDWSIKLWDLSK 102 >5WLC-LJ nrPDB Length = 513 Score = 47.0 bits (110), Expect = 1e-05, Method: Composition-based stats. Identities = 32/189 (16%), Positives = 60/189 (31%), Gaps = 40/189 (21%) Query: 152 SSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPS-LEKVLEFKAHEGEIEDLALGPDGK- 209 S+ P DN +LAT D R+W + + E LE + L+ P Sbjct: 123 STHPTHVTKFHTQDNKILATASDDRVTRLWDISNAYEPQLELTGATDYVRTLSFIPAAPH 182 Query: 210 -LVTVGRDLKASVWQKDQ-----LVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLR 263 + T D ++ + + H Q + +P + +C Sbjct: 183 LVATGSYDGLIRLYDTRSSGSTPIYSLNHDQPVENVIAVSPTQIVSCGGNN--------- 233 Query: 264 LFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSES-----GTFLGLG 318 WD ++ L + ++ V+CLD E+ + L Sbjct: 234 ------------------FKVWDLTSNKKLYERGNFNKAVTCLDYVENFDSPMQSALIAS 275 Query: 319 TVTGSVAIY 327 ++ G V ++ Sbjct: 276 SLDGHVKVF 284 Score = 32.0 bits (71), Expect = 0.43, Method: Composition-based stats. Identities = 18/96 (18%), Positives = 36/96 (37%), Gaps = 10/96 (10%) Query: 155 PLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLAL-----GP-DG 208 P++ V+ + + + G + + +VW + S +K+ E + L P Sbjct: 214 PVENVIAVSPTQ--IVSCGGNNF-KVWDLTSNKKLYERGNFNKAVTCLDYVENFDSPMQS 270 Query: 209 KLVTVGRDLKASVWQ-KDQLVTQLHWQENGPTFSST 243 L+ D V+ D + W+ +GP S Sbjct: 271 ALIASSLDGHVKVFDPLDNFQVKFGWKFSGPVLSCA 306 >5CXC-A nrPDB Length = 510 Score = 46.6 bits (109), Expect = 2e-05, Method: Composition-based stats. Identities = 43/225 (19%), Positives = 72/225 (32%), Gaps = 24/225 (10%) Query: 165 DNTLLATGGTDGYVRVWK-------VPSLEKVLEFKAHEGEIEDLALGPDGK-LVTVGRD 216 + LA+ G D VRVWK L+ LE H G ++ L + K ++T D Sbjct: 202 TSDRLASAGMDRTVRVWKYTESDHFTGELKPTLELYGHTGSVDWLDVDGHSKHILTASAD 261 Query: 217 LKASVWQKDQ---------LVTQLHWQENGPTFSS-TPYRYQACRFGQVPDQPAGLRLFT 266 W + L+ H + SS + + + PA +F Sbjct: 262 GAIGFWSASKASAPEPDASLLPGAHVSKRRKATSSVSTAQRGPLGLWSIHTAPATAAIFD 321 Query: 267 VQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAI 326 + + D + + T + H ++S ++ +GT L S Sbjct: 322 PRDRTVAYSASQDHTVRTLDLTTGQVVSTLTLTHPLLSLSALTRAGTTSPLLAAGTSARH 381 Query: 327 YI-----AFSLQCLYYVREAHGIVVTDVAFLPEKGRGPELLGSHE 366 A S H V ++ PE + GSH+ Sbjct: 382 ITMVDPRASSATTSVMTLRGHANKVVSLSPSPENEYSL-VSGSHD 425 Score = 40.9 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 31/203 (15%), Positives = 55/203 (27%), Gaps = 31/203 (15%) Query: 164 HDNTLLATGGTDGYVRVWKVPSLEKVLE-----FKAHEGEIEDLALGPDGKLVTVGRDLK 218 + + DG +R+W S + H I+ +L + G D Sbjct: 156 PGQERVLSASYDGLLRIWN-ASGSVIATSPSGSHGGHTASIKAAKFLTSDRLASAGMDRT 214 Query: 219 ASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPP 278 VW+ + + E PT +G L L Sbjct: 215 VRVWKYTE--SDHFTGELKPTLEL---------YGHTGSVD---WLDVDGHSKHILTASA 260 Query: 279 PCYLTAWDGS---------NFLPLRTKSCGHEVVSCLDVSESGT--FLGLGTVTGSVAIY 327 + W S + LP S + S + ++ G + T + AI+ Sbjct: 261 DGAIGFWSASKASAPEPDASLLPGAHVSKRRKATSSVSTAQRGPLGLWSIHTAPATAAIF 320 Query: 328 IAFSLQCLYYVREAHGIVVTDVA 350 Y + H + D+ Sbjct: 321 DPRDRTVAYSASQDHTVRTLDLT 343 Score = 28.2 bits (61), Expect = 7.4, Method: Composition-based stats. Identities = 12/47 (25%), Positives = 19/47 (40%), Gaps = 3/47 (6%) Query: 157 QKVVCFNHDNT---LLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIE 200 KVV + L +G DG RVW + S+ + + G + Sbjct: 404 NKVVSLSPSPENEYSLVSGSHDGTCRVWDLRSVRPATKEEGSLGGVS 450 >2HES-X nrPDB Length = 330 Score = 46.6 bits (109), Expect = 2e-05, Method: Composition-based stats. Identities = 18/69 (26%), Positives = 26/69 (37%), Gaps = 5/69 (7%) Query: 160 VCFNHDNTLLATGGTDGYVRVWK--VPSLEKVLEFKAHEGEIEDLALGPDG---KLVTVG 214 V ++ LLA+ D VR+WK E V HEG + +L + Sbjct: 159 VIWHPSEALLASSSYDDTVRIWKDYDDDWECVAVLNGHEGTVWSSDFDKTEGVFRLCSGS 218 Query: 215 RDLKASVWQ 223 D VW+ Sbjct: 219 DDSTVRVWK 227 Score = 45.9 bits (107), Expect = 3e-05, Method: Composition-based stats. Identities = 20/82 (24%), Positives = 32/82 (39%), Gaps = 8/82 (9%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLE-------KVLEFKAHEGEIEDLALGPDGK-LV 211 V + +LLA G D V +W + + HE E++ +A DG L Sbjct: 64 VAWRPHTSLLAAGSFDSTVSIWAKEESADRTFEMDLLAIIEGHENEVKGVAWSNDGYYLA 123 Query: 212 TVGRDLKASVWQKDQLVTQLHW 233 T RD +W+ D+ + Sbjct: 124 TCSRDKSVWIWETDESGEEYEC 145 Score = 27.8 bits (60), Expect = 9.6, Method: Composition-based stats. Identities = 17/69 (24%), Positives = 27/69 (39%), Gaps = 7/69 (10%) Query: 166 NTLLATGGTDGYVRV-------WKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLK 218 N L+A+ G DG + V WKV + + ++ L L L T G D Sbjct: 261 NGLIASVGADGVLAVYEEVDGEWKVFAKRALCHGVYEINVVKWLELNGKTILATGGDDGI 320 Query: 219 ASVWQKDQL 227 + W ++ Sbjct: 321 VNFWSLEKA 329 >5A9Q-0 nrPDB Length = 380 Score = 46.3 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 26/97 (26%), Positives = 36/97 (37%), Gaps = 7/97 (7%) Query: 155 PLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEK-VLEFKAHEGEIEDLALGPDG--KLV 211 PL V + ++ATGG DG + +W V V KAHE E+ ++ P L Sbjct: 219 PLHCVDRHPNQQHVVATGGQDGMLSIWDVRQGTMPVSLLKAHEAEMWEVHFHPSNPEHLF 278 Query: 212 TVGRDLKASVWQKD----QLVTQLHWQENGPTFSSTP 244 T D W + + H TF S Sbjct: 279 TCSEDGSLWHWDASTDVPEKSSLFHQGGRSSTFLSHS 315 Score = 33.2 bits (74), Expect = 0.20, Method: Composition-based stats. Identities = 40/226 (17%), Positives = 70/226 (30%), Gaps = 72/226 (31%) Query: 151 FSSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFK-AHEGEIEDLALGPDGK 209 +SS P VVC +N + T G DG + +++ E V A + + + Sbjct: 129 YSSAPCTGVVC---NNPEIVTVGEDGRINLFRADHKEAVRTIDNADSSTLHAVTFLRTPE 185 Query: 210 LVTVGRDLKASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQI 269 ++TV + +W Q E S T R Sbjct: 186 ILTVNSIGQLKIWDFRQ-----QGNEPSQILSLTGDRVPL-------------------- 220 Query: 270 PHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIA 329 H R P ++ A G + ++S DV + G++ + Sbjct: 221 -HCVDRHPNQQHVVATGGQDG-----------MLSIWDVRQ-----------GTMPV--- 254 Query: 330 FSLQCLYYVREAHGIVVTDVAFLPEKGRGPELLGSHETALFSVAVD 375 + +AH + +V F P S+ LF+ + D Sbjct: 255 -------SLLKAHEAEMWEVHFHP----------SNPEHLFTCSED 283 >4BZK-B nrPDB Length = 297 Score = 46.3 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 33/205 (16%), Positives = 67/205 (32%), Gaps = 22/205 (10%) Query: 163 NHDNTLLATGGTDGYVRVWKV--PSLEKVLEFKAHEGEIEDLALGP---DGKLVTVGRDL 217 ++ LAT +D +++++V + + + HEG + + L + D Sbjct: 18 DYYGKRLATCSSDKTIKIFEVEGETHKLIDTLTGHEGPVWRVDWAHPKFGTILASCSYDG 77 Query: 218 KASVWQKDQ------LVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPH 271 K +W+++ V +H + + P+ Y V + + + Sbjct: 78 KVLIWKEENGRWSQIAVHAVH-SASVNSVQWAPHEYGP--LLLVASSDGKVSVVEFKENG 134 Query: 272 KRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIY---I 328 + + +++ P + G ES F+ G V I+ Sbjct: 135 TTSPIIIDAHAIGVNSASWAPATIEEDGEHN----GTKESRKFV-TGGADNLVKIWKYNS 189 Query: 329 AFSLQCLYYVREAHGIVVTDVAFLP 353 L E H V DVA+ P Sbjct: 190 DAQTYVLESTLEGHSDWVRDVAWSP 214 Score = 45.1 bits (105), Expect = 6e-05, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 27/70 (38%), Gaps = 8/70 (11%) Query: 165 DNTLLATGGTDGYVRVW----KVPSLEKVLEFKAHEGEIEDLALGPD----GKLVTVGRD 216 ++ TGG D V++W + + H + D+A P L +V +D Sbjct: 169 ESRKFVTGGADNLVKIWKYNSDAQTYVLESTLEGHSDWVRDVAWSPTVLLRSYLASVSQD 228 Query: 217 LKASVWQKDQ 226 +W +D Sbjct: 229 RTCIIWTQDN 238 >3JRP-A nrPDB Length = 379 Score = 46.3 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 33/205 (16%), Positives = 67/205 (32%), Gaps = 22/205 (10%) Query: 163 NHDNTLLATGGTDGYVRVWKV--PSLEKVLEFKAHEGEIEDLALGP---DGKLVTVGRDL 217 ++ LAT +D +++++V + + + HEG + + L + D Sbjct: 20 DYYGKRLATCSSDKTIKIFEVEGETHKLIDTLTGHEGPVWRVDWAHPKFGTILASCSYDG 79 Query: 218 KASVWQKDQ------LVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPH 271 K +W+++ V +H + + P+ Y V + + + Sbjct: 80 KVLIWKEENGRWSQIAVHAVH-SASVNSVQWAPHEYGP--LLLVASSDGKVSVVEFKENG 136 Query: 272 KRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIY---I 328 + + +++ P + G ES F+ G V I+ Sbjct: 137 TTSPIIIDAHAIGVNSASWAPATIEEDGEHN----GTKESRKFV-TGGADNLVKIWKYNS 191 Query: 329 AFSLQCLYYVREAHGIVVTDVAFLP 353 L E H V DVA+ P Sbjct: 192 DAQTYVLESTLEGHSDWVRDVAWSP 216 Score = 45.1 bits (105), Expect = 6e-05, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 27/70 (38%), Gaps = 8/70 (11%) Query: 165 DNTLLATGGTDGYVRVW----KVPSLEKVLEFKAHEGEIEDLALGPD----GKLVTVGRD 216 ++ TGG D V++W + + H + D+A P L +V +D Sbjct: 171 ESRKFVTGGADNLVKIWKYNSDAQTYVLESTLEGHSDWVRDVAWSPTVLLRSYLASVSQD 230 Query: 217 LKASVWQKDQ 226 +W +D Sbjct: 231 RTCIIWTQDN 240 >3JRO-A nrPDB Length = 753 Score = 46.3 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 33/205 (16%), Positives = 67/205 (32%), Gaps = 22/205 (10%) Query: 163 NHDNTLLATGGTDGYVRVWKV--PSLEKVLEFKAHEGEIEDLALGP---DGKLVTVGRDL 217 ++ LAT +D +++++V + + + HEG + + L + D Sbjct: 18 DYYGKRLATCSSDKTIKIFEVEGETHKLIDTLTGHEGPVWRVDWAHPKFGTILASCSYDG 77 Query: 218 KASVWQKDQ------LVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPH 271 K +W+++ V +H + + P+ Y V + + + Sbjct: 78 KVLIWKEENGRWSQIAVHAVH-SASVNSVQWAPHEYGP--LLLVASSDGKVSVVEFKENG 134 Query: 272 KRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIY---I 328 + + +++ P + G ES F+ G V I+ Sbjct: 135 TTSPIIIDAHAIGVNSASWAPATIEEDGEHN----GTKESRKFV-TGGADNLVKIWKYNS 189 Query: 329 AFSLQCLYYVREAHGIVVTDVAFLP 353 L E H V DVA+ P Sbjct: 190 DAQTYVLESTLEGHSDWVRDVAWSP 214 Score = 45.1 bits (105), Expect = 6e-05, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 27/70 (38%), Gaps = 8/70 (11%) Query: 165 DNTLLATGGTDGYVRVW----KVPSLEKVLEFKAHEGEIEDLALGPD----GKLVTVGRD 216 ++ TGG D V++W + + H + D+A P L +V +D Sbjct: 169 ESRKFVTGGADNLVKIWKYNSDAQTYVLESTLEGHSDWVRDVAWSPTVLLRSYLASVSQD 228 Query: 217 LKASVWQKDQ 226 +W +D Sbjct: 229 RTCIIWTQDN 238 >4AEZ-A nrPDB Length = 401 Score = 45.9 bits (107), Expect = 3e-05, Method: Composition-based stats. Identities = 24/163 (14%), Positives = 52/163 (31%), Gaps = 10/163 (6%) Query: 158 KVVCFNHDNTLLATGGTDGYVRVWK--VPSLEKVLEFKAHEGEIEDLALGPDG-KLVTVG 214 +V C + + +L++G G + + + + + + H E+ LA DG +L + G Sbjct: 178 RVGCLSWNRHVLSSGSRSGAIHHHDVRIANHQ-IGTLQGHSSEVCGLAWRSDGLQLASGG 236 Query: 215 RDLKASVWQKDQ---LVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPH 271 D +W T+ + + P++ G + + Sbjct: 237 NDNVVQIWDARSSIPKFTKTNHNAAVKAVAWCPWQSNLLATG-GGTMDKQIHFWNAATGA 295 Query: 272 K--RLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESG 312 + + W + + T +S S SG Sbjct: 296 RVNTVDAGSQVTSLIWSPHSKEIMSTHGFPDNNLSIWSYSSSG 338 Score = 40.1 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 20/85 (23%), Positives = 35/85 (41%), Gaps = 8/85 (9%) Query: 164 HDNTLLATGGT-DGYVRVWKVPSLEKVLEFK--AHEGEIEDLALGPDGKLV-TVGRDLKA 219 H +++T G D + +W S + AH+ + AL PDG+++ T D Sbjct: 314 HSKEIMSTHGFPDNNLSIWSYSSSGLTKQVDIPAHDTRVLYSALSPDGRILSTAASDENL 373 Query: 220 SVWQKDQLVTQLHWQENGPTFSSTP 244 W ++ H + P + TP Sbjct: 374 KFW---RVYDGDHVKRPIP-ITKTP 394 >3ACP-A nrPDB Length = 417 Score = 45.5 bits (106), Expect = 4e-05, Method: Composition-based stats. Identities = 12/78 (15%), Positives = 26/78 (33%), Gaps = 1/78 (1%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK-LVTVGRDLKAS 220 F L + D +++W V H + D+A+ G+ +++ D Sbjct: 144 FFPSGEALISSSQDMQLKIWSVKDGSNPRTLIGHRATVTDIAIIDRGRNVLSASLDGTIR 203 Query: 221 VWQKDQLVTQLHWQENGP 238 +W+ T + Sbjct: 204 LWECGTGTTIHTFNRKEN 221 Score = 39.7 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 37/179 (20%), Positives = 65/179 (36%), Gaps = 24/179 (13%) Query: 169 LATGGTDGYVRVWKVPSLEKVLEFK-AHEGEIEDLALGPDGK-LVTVGRDLKASVW---Q 223 G T+G ++V + E AH EI L P G+ L++ +D++ +W Sbjct: 109 FILGTTEGDIKVLD-SNFNLQREIDQAHVSEITKLKFFPSGEALISSSQDMQLKIWSVKD 167 Query: 224 KDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLF---TVQIPHKRLRQPPPC 280 T + + + R +RL+ T H R+ P Sbjct: 168 GSNPRTLIGHRATVTDIAII----DRGRNVLSASLDGTIRLWECGTGTTIHTFNRKENPH 223 Query: 281 YLTAWDGSNFLPLR--TKSCGHEVVSC----LDVSESGTFLGLGTVTGSVAIYIAFSLQ 333 DG N + L T HE+ + L+ G ++ G V+G + ++ FS + Sbjct: 224 -----DGVNSIALFVGTDRQLHEISTSKKNNLEFGTYGKYVIAGHVSGVITVHNVFSKE 277 >6CHG-D nrPDB Length = 439 Score = 45.1 bits (105), Expect = 6e-05, Method: Composition-based stats. Identities = 21/98 (21%), Positives = 40/98 (40%), Gaps = 20/98 (20%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEG----EIEDLALGPDGKLV-TVGRD 216 F+ LA G ++G + ++ + SL+ + H G ++ + DG+ + + GRD Sbjct: 35 FSPRGDYLAVGCSNGAIIIYDMDSLKPIAMLGTHSGAHTRSVQSVCWSNDGRYLWSSGRD 94 Query: 217 LKASVWQKDQLVTQLHWQENGPTFSSTPYRY----QAC 250 A +W Q PT Y++ +C Sbjct: 95 WYAKLWDMTQ-----------PTKCFQQYKFDGPLWSC 121 >4GGA-A nrPDB Length = 420 Score = 44.7 bits (104), Expect = 7e-05, Method: Composition-based stats. Identities = 15/52 (28%), Positives = 24/52 (46%), Gaps = 1/52 (1%) Query: 172 GGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDG-KLVTVGRDLKASVW 222 G + +WK P++ KV E K H + L + PDG + + D +W Sbjct: 340 GFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLW 391 Score = 37.4 bits (85), Expect = 0.011, Method: Composition-based stats. Identities = 33/250 (13%), Positives = 66/250 (26%), Gaps = 38/250 (15%) Query: 165 DNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQK 224 + LA G + V++W V +++ +H + L+ + + Sbjct: 158 EGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWN---SYILSSGSRSGHIHHH 214 Query: 225 DQLVTQLH---------------WQENGPTFSSTPY----RYQACRFGQVPDQPAGLRLF 265 D V + H W +G +S G+ P L Sbjct: 215 DVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVP----LQ 270 Query: 266 TVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVA 325 T ++ C W + S H + +V L V Sbjct: 271 TFTQHQGAVKAVAWC---PWQSNVLATGGGTSDRH--IRIWNVCSGA---CLSAVDAHSQ 322 Query: 326 IYIAFSLQCLYYVREAHGIVVTDVAF--LPEKGRGPELLGSHETALFSVAVDSRCQLHLL 383 + + HG + P + E L H + + S+ + Sbjct: 323 VCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAE-LKGHTSRVLSLTMSPDGATVAS 381 Query: 384 PSRR-SVPVW 392 + ++ +W Sbjct: 382 AAADETLRLW 391 >5LCW-Q nrPDB Length = 374 Score = 44.7 bits (104), Expect = 7e-05, Method: Composition-based stats. Identities = 15/52 (28%), Positives = 24/52 (46%), Gaps = 1/52 (1%) Query: 172 GGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDG-KLVTVGRDLKASVW 222 G + +WK P++ KV E K H + L + PDG + + D +W Sbjct: 294 GFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLW 345 Score = 37.4 bits (85), Expect = 0.011, Method: Composition-based stats. Identities = 33/250 (13%), Positives = 66/250 (26%), Gaps = 38/250 (15%) Query: 165 DNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQK 224 + LA G + V++W V +++ +H + L+ + + Sbjct: 112 EGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWN---SYILSSGSRSGHIHHH 168 Query: 225 DQLVTQLH---------------WQENGPTFSSTPY----RYQACRFGQVPDQPAGLRLF 265 D V + H W +G +S G+ P L Sbjct: 169 DVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVP----LQ 224 Query: 266 TVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVA 325 T ++ C W + S H + +V L V Sbjct: 225 TFTQHQGAVKAVAWC---PWQSNVLATGGGTSDRH--IRIWNVCSGA---CLSAVDAHSQ 276 Query: 326 IYIAFSLQCLYYVREAHGIVVTDVAF--LPEKGRGPELLGSHETALFSVAVDSRCQLHLL 383 + + HG + P + E L H + + S+ + Sbjct: 277 VCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAE-LKGHTSRVLSLTMSPDGATVAS 335 Query: 384 PSRR-SVPVW 392 + ++ +W Sbjct: 336 AAADETLRLW 345 >5G04-R nrPDB Length = 499 Score = 44.7 bits (104), Expect = 7e-05, Method: Composition-based stats. Identities = 15/52 (28%), Positives = 24/52 (46%), Gaps = 1/52 (1%) Query: 172 GGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDG-KLVTVGRDLKASVW 222 G + +WK P++ KV E K H + L + PDG + + D +W Sbjct: 419 GFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLW 470 Score = 37.4 bits (85), Expect = 0.011, Method: Composition-based stats. Identities = 33/250 (13%), Positives = 66/250 (26%), Gaps = 38/250 (15%) Query: 165 DNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQK 224 + LA G + V++W V +++ +H + L+ + + Sbjct: 237 EGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWN---SYILSSGSRSGHIHHH 293 Query: 225 DQLVTQLH---------------WQENGPTFSSTPY----RYQACRFGQVPDQPAGLRLF 265 D V + H W +G +S G+ P L Sbjct: 294 DVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVP----LQ 349 Query: 266 TVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVA 325 T ++ C W + S H + +V L V Sbjct: 350 TFTQHQGAVKAVAWC---PWQSNVLATGGGTSDRH--IRIWNVCSGA---CLSAVDAHSQ 401 Query: 326 IYIAFSLQCLYYVREAHGIVVTDVAF--LPEKGRGPELLGSHETALFSVAVDSRCQLHLL 383 + + HG + P + E L H + + S+ + Sbjct: 402 VCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAE-LKGHTSRVLSLTMSPDGATVAS 460 Query: 384 PSRR-SVPVW 392 + ++ +W Sbjct: 461 AAADETLRLW 470 >4N14-A nrPDB Length = 314 Score = 44.7 bits (104), Expect = 7e-05, Method: Composition-based stats. Identities = 15/52 (28%), Positives = 24/52 (46%), Gaps = 1/52 (1%) Query: 172 GGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDG-KLVTVGRDLKASVW 222 G + +WK P++ KV E K H + L + PDG + + D +W Sbjct: 256 GFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLW 307 Score = 37.4 bits (85), Expect = 0.012, Method: Composition-based stats. Identities = 33/250 (13%), Positives = 66/250 (26%), Gaps = 38/250 (15%) Query: 165 DNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQK 224 + LA G + V++W V +++ +H + L+ + + Sbjct: 74 EGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWN---SYILSSGSRSGHIHHH 130 Query: 225 DQLVTQLH---------------WQENGPTFSSTPY----RYQACRFGQVPDQPAGLRLF 265 D V + H W +G +S G+ P L Sbjct: 131 DVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVP----LQ 186 Query: 266 TVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVA 325 T ++ C W + S H + +V L V Sbjct: 187 TFTQHQGAVKAVAWC---PWQSNVLATGGGTSDRH--IRIWNVCSGA---CLSAVDAHSQ 238 Query: 326 IYIAFSLQCLYYVREAHGIVVTDVAF--LPEKGRGPELLGSHETALFSVAVDSRCQLHLL 383 + + HG + P + E L H + + S+ + Sbjct: 239 VCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAE-LKGHTSRVLSLTMSPDGATVAS 297 Query: 384 PSRR-SVPVW 392 + ++ +W Sbjct: 298 AAADETLRLW 307 >5YZG-2 nrPDB Length = 646 Score = 44.3 bits (103), Expect = 9e-05, Method: Composition-based stats. Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 5/73 (6%) Query: 154 DPLQKVVCFNHDNTLLATGGTDGYVRVWKV--PSLEKVLEFKAHEGEIEDLALGPDGKL- 210 D + VVC + T DG+V+ WK +E V F++H G IE +A+ +G L Sbjct: 91 DVITHVVC--TKTDFIITASHDGHVKFWKKIEEGIEFVKHFRSHLGVIESIAVSSEGALF 148 Query: 211 VTVGRDLKASVWQ 223 +VG D V+ Sbjct: 149 CSVGDDKAMKVFD 161 Score = 37.0 bits (84), Expect = 0.014, Method: Composition-based stats. Identities = 11/34 (32%), Positives = 20/34 (58%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFK 193 VCF+ D +AT G+D VR+++ + + + F Sbjct: 286 VCFSPDGKKIATIGSDRKVRIFRFVTGKLMRVFD 319 Score = 32.0 bits (71), Expect = 0.51, Method: Composition-based stats. Identities = 11/43 (25%), Positives = 20/43 (46%), Gaps = 1/43 (2%) Query: 181 WKVPSLEKVLEFKAHEGEIEDLALGPDG-KLVTVGRDLKASVW 222 W+ + + EF + + PDG K+ T+G D K ++ Sbjct: 265 WEYKTDTDLYEFAKCKAYPTSVCFSPDGKKIATIGSDRKVRIF 307 >4L9O-A nrPDB Length = 349 Score = 44.3 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 20/95 (21%), Positives = 40/95 (42%), Gaps = 10/95 (10%) Query: 163 NHDNTLLATGGTDGYVRVWKV--PSLEKVLEFKAHEGEIEDLALG-PDGK--LVTVGRDL 217 ++ LAT +D ++++++ + V HEG + +A P L + D Sbjct: 78 DYYGRRLATCSSDKTIKIFEIDGENQRLVETLIGHEGPVWQVAWAHPKFGVILASCSYDG 137 Query: 218 KASVWQKD----QLVTQLHW-QENGPTFSSTPYRY 247 K +W++D V + Q + + S P+ Y Sbjct: 138 KVLIWKEDNGVWNKVAEHSVHQASVNSVSWAPHEY 172 Score = 43.6 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 19/101 (18%), Positives = 35/101 (34%), Gaps = 10/101 (9%) Query: 165 DNTLLATGGTDGYVRVWKVPSLEKVL----EFKAHEGEIEDLALGPD----GKLVTVGRD 216 + +GG D V++W+ K F+ H + D+A P + T +D Sbjct: 221 NTRRFVSGGCDNLVKIWRYDDAAKTFIEEEAFQGHSDWVRDVAWSPSRLSKSYIATASQD 280 Query: 217 LKASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPD 257 +W KD + W++ T P + + Sbjct: 281 RTVLIWTKDGKSNK--WEKQPLTKEKFPDVCWRASWSLSGN 319 Score = 41.3 bits (95), Expect = 9e-04, Method: Composition-based stats. Identities = 43/263 (16%), Positives = 79/263 (30%), Gaps = 70/263 (26%) Query: 128 CGAETQHEGLELRVENLQAVQTDFSSD-PLQKVVCFNHD-NTLLATGGTDGYVRVWKVPS 185 C ++ + E+ EN + V+T + P+ +V + +LA+ DG V +WK + Sbjct: 87 CSSDKTIKIFEIDGENQRLVETLIGHEGPVWQVAWAHPKFGVILASCSYDGKVLIWKEDN 146 Query: 186 L--EKVLEFKAHEGEIEDLALGP------------DGK---------------------- 209 KV E H+ + ++ P DGK Sbjct: 147 GVWNKVAEHSVHQASVNSVSWAPHEYGPVLLCASSDGKISIVEFKDGGALEPIVIQGHAI 206 Query: 210 ------------------LVTVGRDLKASVWQKDQL----VTQLHWQ---ENGPTFSSTP 244 V+ G D +W+ D + + +Q + + +P Sbjct: 207 GVNAASWAPISLPDNTRRFVSGGCDNLVKIWRYDDAAKTFIEEEAFQGHSDWVRDVAWSP 266 Query: 245 YRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPP----PCYLTAWDGSNFLPLRTK--SC 298 R + Q + ++T + + P W S L S Sbjct: 267 SRLSK-SYIATASQDRTVLIWTKDGKSNKWEKQPLTKEKFPDVCWRASWSLSGNVLAISG 325 Query: 299 GHEVVSCLDVSESGTFLGLGTVT 321 G V+ + G + G V Sbjct: 326 GDNKVTLWKENIQGKWESAGEVD 348 >5M89-A nrPDB Length = 329 Score = 43.9 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 41/234 (17%), Positives = 77/234 (32%), Gaps = 32/234 (13%) Query: 125 EKKCGAETQHEGLELRVENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVP 184 E +C A +G +L + ++ A + + + D + V T + G G+V+V+ Sbjct: 62 ENECAAVGGLDG-KLDIYSVVANKVERTLDIGEPVTATEWTGTKVVIGTAKGWVKVYDAG 120 Query: 185 SLEKVLEFKAHEGEIEDLALGPDGK-LVTVGRDLKASVWQKD--QLVTQLHWQENGPTFS 241 F+ H G + LA+ P G+ L +VG D + + + V + + T + Sbjct: 121 RES--ATFQTHAGPVTGLAVHPGGRILASVGVDKSFVFYDLETGERVARGYADAALTTCA 178 Query: 242 STPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLT-----AWDGSNFL----- 291 P Q T++ P L W + Sbjct: 179 FHPDGNLFAAGTQTGHILV-FHTTTLEQAESFPLGTPIQALAFSENGFWFAATGKGTSSV 237 Query: 292 ------------PLRTKSCGHEVVSCLDVSESGTFLGLGTVTG-SVAIYIAFSL 332 ++ G + D +G +L G TG +V +Y + Sbjct: 238 TIFDLRKSGAAAAVKELQTGEVLSISWDY--TGQYLATGGGTGVTVQMYTKATK 289 >5L9T-R nrPDB Length = 493 Score = 43.9 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 40/202 (19%), Positives = 65/202 (32%), Gaps = 36/202 (17%) Query: 147 VQTDFSSDPLQ---------KVVC---FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKA 194 +Q D + PLQ + VC ++ D+ LLA+GG D + VW SL V ++ Sbjct: 294 LQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTE 353 Query: 195 HEGEIEDLALGP--DGKLVTVG--RDLKASVWQKDQLVTQLHWQENGPTFSSTPYRYQAC 250 H ++ +A P G L + G D W T + P + C Sbjct: 354 HLAAVKAIAWSPHQHGLLASGGGTADRCIRFW---------------NTLTGQPLQ---C 395 Query: 251 RFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSE 310 Q L + W + + + V L +S Sbjct: 396 --IDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSP 453 Query: 311 SGTFLGLGTVTGSVAIYIAFSL 332 G + G ++ + FS Sbjct: 454 DGEAIVTGAGDETLRFWNVFSK 475 Score = 39.7 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 34/244 (13%), Positives = 77/244 (31%), Gaps = 23/244 (9%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASV 221 ++ L+A G G+V++W + +K+ + H + LA + +L + RD Sbjct: 237 WSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAE-QLSSGSRDRMILQ 295 Query: 222 WQ-------KDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRL 274 ++ + + G +S+ +Q G ++ ++ + Sbjct: 296 RDIRTPPLQSERRLQGHRQEVCGLKWST---DHQLLASGGNDNKLLVWNHSSLSPVQQYT 352 Query: 275 RQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQC 334 AW S S G C+ + T L + + + Sbjct: 353 EHLAAVKAIAW--SPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKH 410 Query: 335 LYYVREAHG-----IVVTDVAFLPEKGRGPELLGSHETALFSVAVDSRCQLHLLPS-RRS 388 + HG I+V L + + L H + +A+ + + + + Sbjct: 411 ANELVSTHGYSQNQILVWKYPSLTQVAK----LTGHSYRVLYLAMSPDGEAIVTGAGDET 466 Query: 389 VPVW 392 + W Sbjct: 467 LRFW 470 >4XFV-A nrPDB Length = 792 Score = 43.6 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 44/245 (17%), Positives = 76/245 (31%), Gaps = 51/245 (20%) Query: 164 HDNTLLATGGTDGYVRVWKV--PSLEKVL-EFKAHEGEIEDLALGPDGKL-VTVGRDLKA 219 H + G + +W P+ + V K HE E+ + PD V+ D Sbjct: 28 HKVKKIVAFGAGKTIALWDPIEPNNKGVYATLKGHEAEVTCVRFVPDSDFMVSASEDHHV 87 Query: 220 SVWQ------KDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKR 273 +W+ + T H+ + S+ P V + ++ I + Sbjct: 88 KIWKFTDYSHLQCIQTIQHYSKTIVALSALP------SLISVGCADGTISIWRQNIQNDE 141 Query: 274 LRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGS-VAIYIAFSL 332 T G CL +S+ L + G+ V ++IA Sbjct: 142 FGLAHE--------------FTIKKGFFYPLCLSLSKVEEKKYLLAIGGTNVNVFIA--- 184 Query: 333 QCLYYVREAHGIVVTDVAFLPEKGRGPELLGSHETALFSVAVDSRCQ----LHLLPSR-R 387 ++ GI EK R L HE + S+A + L S+ R Sbjct: 185 ---SFILSDSGI---------EKCRVVAELEGHEDWVKSLAFRHQETPGDYLLCSGSQDR 232 Query: 388 SVPVW 392 + +W Sbjct: 233 YIRLW 237 Score = 39.3 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 17/74 (22%), Positives = 35/74 (47%), Gaps = 8/74 (10%) Query: 158 KVVC--FNHDNTLLATGGTDGYVRVW---KVPSLEKVLEFKAHEGEIEDLALGPDGKLVT 212 +V C F D+ + + D +V++W L+ + + + I L+ P L++ Sbjct: 65 EVTCVRFVPDSDFMVSASEDHHVKIWKFTDYSHLQCIQTIQHYSKTIVALSALP--SLIS 122 Query: 213 VG-RDLKASVWQKD 225 VG D S+W+++ Sbjct: 123 VGCADGTISIWRQN 136 Score = 32.8 bits (73), Expect = 0.28, Method: Composition-based stats. Identities = 28/175 (16%), Positives = 45/175 (25%), Gaps = 30/175 (17%) Query: 189 VLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQKDQLVTQLHWQENGPTFSSTPYRYQ 248 V + H EI L + PD KL+ ++ + +W E P Sbjct: 555 VEKLYGHGFEITCLDISPDQKLIASACRSNNVQNAVIRIFSTENWLEIKPALPFHSLTIT 614 Query: 249 ACRFGQVPDQPAGL----------RLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSC 298 +F + + R R + P WD Sbjct: 615 RLKFSKDGKFLLSVCRDRKWALWERNMEDNTFELRFKNEKPHTRIIWDAD---------- 664 Query: 299 GHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYVREA---HGIVVTDVA 350 E G + +V ++ YV EA H VT ++ Sbjct: 665 -------WAPLEFGNVFVTASRDKTVKVWRHQKEPADDYVLEASIKHTKAVTAIS 712 >4YCZ-A nrPDB Length = 876 Score = 42.8 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 18/111 (16%), Positives = 44/111 (39%), Gaps = 11/111 (9%) Query: 145 QAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRVWKV--PSLEKVLEFKAHEGEIEDL 202 Q + D + V ++ LAT +D ++++++ + K H+G + + Sbjct: 10 QVIANSGHDDMIHDAV-LDYYGRRLATCSSDRTIKIFEIEGETQRLTETLKGHDGAVWCV 68 Query: 203 ALG--PDGK-LVTVGRDLKASVWQK-----DQLVTQLHWQENGPTFSSTPY 245 + G L + G D K +W++ ++ + + S +P+ Sbjct: 69 SWAHPKYGNILASAGYDGKVLIWRELNGAWQRIFDFALHKASVNVVSWSPH 119 Score = 41.6 bits (96), Expect = 7e-04, Method: Composition-based stats. Identities = 18/90 (20%), Positives = 31/90 (34%), Gaps = 10/90 (11%) Query: 166 NTLLATGGTDGYVRVW----KVPSLEKVLE-FKAHEGEIEDLALGP----DGKLVTVGRD 216 N TGG+D +++W + + E H + D+A P + + D Sbjct: 182 NRRFVTGGSDNALKIWAYDPATNTYKLEREPLTGHTDWVRDVAWSPTVLQKSYIASASED 241 Query: 217 LKASVWQKDQLVTQLHWQENGPTFSSTPYR 246 +W D L W F + +R Sbjct: 242 RTVRIWTSDPA-NPLQWNCKVLNFDAAVWR 270 Score = 35.9 bits (81), Expect = 0.034, Method: Composition-based stats. Identities = 32/180 (17%), Positives = 62/180 (34%), Gaps = 22/180 (12%) Query: 166 NTLLATGGTDGYVRVWKVPSL--EKVLEFKAHEGEIEDLALGPDGK---LVTVGRDLKAS 220 +LA+ G DG V +W+ + +++ +F H+ + ++ P L D S Sbjct: 76 GNILASAGYDGKVLIWRELNGAWQRIFDFALHKASVNVVSWSPHEAGCLLACASSDGNVS 135 Query: 221 VW---QKDQLVTQLHWQENG-PTFSSTP-YRYQACRFGQVPDQPAGLRLFTVQIPHKRLR 275 V + H G + S P + + + G R F L+ Sbjct: 136 VLEFRDNSWEHSIFHAHGLGVNSVSWAPATSPGSIVSSKPGPKSTGNRRFVTGGSDNALK 195 Query: 276 QPPPCYLTAWD-GSNFLPLRTKSCGHEVVSCLDVSESGT-----FLGLGTVTGSVAIYIA 329 + A+D +N L + DV+ S T ++ + +V I+ + Sbjct: 196 ------IWAYDPATNTYKLEREPLTGHTDWVRDVAWSPTVLQKSYIASASEDRTVRIWTS 249 Score = 32.0 bits (71), Expect = 0.48, Method: Composition-based stats. Identities = 30/190 (15%), Positives = 55/190 (28%), Gaps = 32/190 (16%) Query: 163 NHDNTLLATGGTDGYVRVWKVPSLEKVLE-FKAHEGEIEDLALGP--------------- 206 + LLA +DG V V + F AH + ++ P Sbjct: 119 HEAGCLLACASSDGNVSVLEFRDNSWEHSIFHAHGLGVNSVSWAPATSPGSIVSSKPGPK 178 Query: 207 ---DGKLVTVGRDLKASVWQKDQLVTQLHWQ--------ENGPTFSSTPYRYQACRFGQV 255 + + VT G D +W D + + + +P Q + Sbjct: 179 STGNRRFVTGGSDNALKIWAYDPATNTYKLEREPLTGHTDWVRDVAWSPTVLQK-SYIAS 237 Query: 256 PDQPAGLRLFTVQ--IPHKRLRQPPPCYLTAWDGSNFLPLRTK--SCGHEVVSCLDVSES 311 + +R++T P + + W S L S G V+ + Sbjct: 238 ASEDRTVRIWTSDPANPLQWNCKVLNFDAAVWRVSWSLSGNVLAASGGDNKVTLWKENLK 297 Query: 312 GTFLGLGTVT 321 G + + T+ Sbjct: 298 GEWECVKTIE 307 Score = 30.5 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 31/181 (17%), Positives = 59/181 (32%), Gaps = 20/181 (11%) Query: 182 KVPSLEKVLEFKAHEGEIEDLALGPDGK-LVTVGRDLKASVWQKD---QLVTQLHWQENG 237 + + +V+ H+ I D L G+ L T D +++ + Q +T+ +G Sbjct: 4 SMAAGTQVIANSGHDDMIHDAVLDYYGRRLATCSSDRTIKIFEIEGETQRLTETLKGHDG 63 Query: 238 PTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKS 297 + + A P + ++ AW Sbjct: 64 AVWCVS----WA--------HPKYGNILASAGYDGKVLIWRE-LNGAW--QRIFDFALHK 108 Query: 298 CGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEKGR 357 VVS E+G L + G+V++ + + AHG+ V V++ P Sbjct: 109 ASVNVVS-WSPHEAGCLLACASSDGNVSVLEFRDNSWEHSIFHAHGLGVNSVSWAPATSP 167 Query: 358 G 358 G Sbjct: 168 G 168 >3JZG-A nrPDB Length = 402 Score = 42.0 bits (97), Expect = 4e-04, Method: Composition-based stats. Identities = 15/63 (23%), Positives = 29/63 (46%), Gaps = 2/63 (3%) Query: 163 NHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK--LVTVGRDLKAS 220 N + LLA G+ G +R+ +++ + + H I +L P L++V +D Sbjct: 118 NTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALR 177 Query: 221 VWQ 223 +W Sbjct: 178 LWN 180 Score = 37.8 bits (86), Expect = 0.009, Method: Composition-based stats. Identities = 16/97 (16%), Positives = 38/97 (39%), Gaps = 7/97 (7%) Query: 154 DPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEF---KAHEGEIEDLALGPDG-K 209 + + ++ D LL + D +R+W + + V F + H E+ G K Sbjct: 152 NAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEK 211 Query: 210 LVTVGRDLKASVWQKDQLVTQLHWQENGPTFSSTPYR 246 +++ G D +W ++ ++ ++ P + Sbjct: 212 IMSCGMDHSLKLW---RINSKRMMNAIKESYDYNPNK 245 >5WLC-SG nrPDB Length = 573 Score = 41.6 bits (96), Expect = 6e-04, Method: Composition-based stats. Identities = 40/222 (18%), Positives = 73/222 (32%), Gaps = 29/222 (13%) Query: 163 NHDNTLLATGGTDGYVRVWKVPSLEKVLEF--KAHEGEIEDLALGPDGKLVTVG-RDLKA 219 + D + TGG D + VW SL V K GE+ LA + + D K Sbjct: 245 SPDGKYVVTGGRDRKLIVWSTESLSPVKVIPTKDRRGEVLSLAFRKNSDQLYASCADFKI 304 Query: 220 SVWQKDQ-----LVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHK-- 272 + +Q ++ H + S+ R V + L+ + + Sbjct: 305 RTYSINQFSQLEILYGHH--DIVEDISALA----MERCVTVGARDRTAMLWKIPDETRLT 358 Query: 273 -RLRQPPPCYLTAW------DGSNFLPLRTKSCGHEVVSCLDVSESGTFLG-----LGTV 320 R P L W +G + + C + + + G+ Sbjct: 359 FRGGDEPQKLLRRWMKENAKEGEDGEVKYPDESEAPLFFCEGSIDVVSMVDDFHFITGSD 418 Query: 321 TGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEKGRGPELL 362 G++ ++ + ++ R AHGI + + +F G E L Sbjct: 419 NGNICLWSLAKKKPIFTERIAHGI-LPEPSFNDISGETDEEL 459 Score = 39.3 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 19/55 (34%), Positives = 23/55 (41%), Gaps = 1/55 (1%) Query: 174 TDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKL-VTVGRDLKASVWQKDQL 227 G + E + H EI +A PDGK VT GRD K VW + L Sbjct: 214 AKGGAKYIPTSKHEYENTTEGHYDEILTVAASPDGKYVVTGGRDRKLIVWSTESL 268 Score = 36.2 bits (82), Expect = 0.023, Method: Composition-based stats. Identities = 20/85 (23%), Positives = 38/85 (44%), Gaps = 3/85 (3%) Query: 142 ENLQAVQTDFSSDPLQKVV--CFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEI 199 E+L V+ + D +V+ F ++ L D +R + + ++ H + Sbjct: 266 ESLSPVKVIPTKDRRGEVLSLAFRKNSDQLYASCADFKIRTYSINQFSQLEILYGHHDIV 325 Query: 200 EDLALGPDGKLVTVG-RDLKASVWQ 223 ED++ + VTVG RD A +W+ Sbjct: 326 EDISALAMERCVTVGARDRTAMLWK 350 Score = 34.3 bits (77), Expect = 0.11, Method: Composition-based stats. Identities = 11/48 (22%), Positives = 22/48 (45%), Gaps = 4/48 (8%) Query: 166 NTLLATGGTDGYVRVWKVP----SLEKVLEFKAHEGEIEDLALGPDGK 209 + + +G G ++VWK+ S E + E +G + + + GK Sbjct: 484 SNVFISGSWSGSLKVWKISDNLRSFELLGELSGAKGVVTKIQVVESGK 531 >4J0X-A nrPDB Length = 451 Score = 41.6 bits (96), Expect = 6e-04, Method: Composition-based stats. Identities = 40/222 (18%), Positives = 73/222 (32%), Gaps = 29/222 (13%) Query: 163 NHDNTLLATGGTDGYVRVWKVPSLEKVLEF--KAHEGEIEDLALGPDGKLVTVG-RDLKA 219 + D + TGG D + VW SL V K GE+ LA + + D K Sbjct: 123 SPDGKYVVTGGRDRKLIVWSTESLSPVKVIPTKDRRGEVLSLAFRKNSDQLYASCADFKI 182 Query: 220 SVWQKDQ-----LVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHK-- 272 + +Q ++ H + S+ R V + L+ + + Sbjct: 183 RTYSINQFSQLEILYGHH--DIVEDISALA----MERCVTVGARDRTAMLWKIPDETRLT 236 Query: 273 -RLRQPPPCYLTAW------DGSNFLPLRTKSCGHEVVSCLDVSESGTFLG-----LGTV 320 R P L W +G + + C + + + G+ Sbjct: 237 FRGGDEPQKLLRRWMKENAKEGEDGEVKYPDESEAPLFFCEGSIDVVSMVDDFHFITGSD 296 Query: 321 TGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEKGRGPELL 362 G++ ++ + ++ R AHGI + + +F G E L Sbjct: 297 NGNICLWSLAKKKPIFTERIAHGI-LPEPSFNDISGETDEEL 337 Score = 39.3 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 19/55 (34%), Positives = 23/55 (41%), Gaps = 1/55 (1%) Query: 174 TDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKL-VTVGRDLKASVWQKDQL 227 G + E + H EI +A PDGK VT GRD K VW + L Sbjct: 92 AKGGAKYIPTSKHEYENTTEGHYDEILTVAASPDGKYVVTGGRDRKLIVWSTESL 146 Score = 36.2 bits (82), Expect = 0.023, Method: Composition-based stats. Identities = 20/85 (23%), Positives = 38/85 (44%), Gaps = 3/85 (3%) Query: 142 ENLQAVQTDFSSDPLQKVV--CFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEI 199 E+L V+ + D +V+ F ++ L D +R + + ++ H + Sbjct: 144 ESLSPVKVIPTKDRRGEVLSLAFRKNSDQLYASCADFKIRTYSINQFSQLEILYGHHDIV 203 Query: 200 EDLALGPDGKLVTVG-RDLKASVWQ 223 ED++ + VTVG RD A +W+ Sbjct: 204 EDISALAMERCVTVGARDRTAMLWK 228 Score = 34.3 bits (77), Expect = 0.11, Method: Composition-based stats. Identities = 11/48 (22%), Positives = 22/48 (45%), Gaps = 4/48 (8%) Query: 166 NTLLATGGTDGYVRVWKVP----SLEKVLEFKAHEGEIEDLALGPDGK 209 + + +G G ++VWK+ S E + E +G + + + GK Sbjct: 362 SNVFISGSWSGSLKVWKISDNLRSFELLGELSGAKGVVTKIQVVESGK 409 >4A11-B nrPDB Length = 408 Score = 41.6 bits (96), Expect = 6e-04, Method: Composition-based stats. Identities = 38/223 (17%), Positives = 65/223 (29%), Gaps = 31/223 (13%) Query: 165 DNTLLATGGTDGYVRVWKVPS------------LEKVLEF-KAHEGEIEDLALGPD--GK 209 + + +GG+DG + ++ + + + H +E + P G Sbjct: 55 EGRYMLSGGSDGVIVLYDLENSSRQSYYTCKAVCSIGRDHPDVHRYSVETVQWYPHDTGM 114 Query: 210 LVTVGRDLKASVWQKDQLVT--QLHWQENGPTFSSTPYRYQAC--RFGQVPDQPAGLRLF 265 + D VW + L T +++E + +P + C G + L Sbjct: 115 FTSSSFDKTLKVWDTNTLQTADVFNFEETVYSHHMSPVSTKHCLVAVGTRGPKVQLCDLK 174 Query: 266 TVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSE-SGTFLGLGTVTGSV 324 + H +W L T S V DV SG + L G Sbjct: 175 SGSCSHILQGHRQEILAVSWSPRYDYILATASADSRV-KLWDVRRASGCLITLDQHNGKK 233 Query: 325 AIYIAFSLQCLYYVREAHGIVVTDVAFLPEKGRGPELLGSHET 367 + Q + AH V + F G LL Sbjct: 234 S-------QAVESANTAHNGKVNGLCF---TSDGLHLLTVGTD 266 Score = 41.3 bits (95), Expect = 8e-04, Method: Composition-based stats. Identities = 39/284 (13%), Positives = 70/284 (24%), Gaps = 82/284 (28%) Query: 156 LQKVVCFNHDNTLLATGGTDGYVRVW---------------------------------- 181 ++ V + HD + + D ++VW Sbjct: 102 VETVQWYPHDTGMFTSSSFDKTLKVWDTNTLQTADVFNFEETVYSHHMSPVSTKHCLVAV 161 Query: 182 ----------KVPSLEKVLEFKAHEGEIEDLALGP--DGKLVTVGRDLKASVWQKDQLVT 229 + S + H EI ++ P D L T D + +W + Sbjct: 162 GTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWSPRYDYILATASADSRVKLWDVRRA-- 219 Query: 230 QLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSN 289 C + + C+ + DG + Sbjct: 220 ------------------SGCLITLDQHNGKKSQAVESANTAHNGKVNGLCFTS--DGLH 259 Query: 290 FLPLRTKSCGHEVVSCLDVSE-SGTFLGLGTVTGSVAIYIAFSLQC-----LYYVREAHG 343 L + T + + + S T + G V + + F++ C +V Sbjct: 260 LLTVGTDNR----MRLWNSSNGENTLVNYGKVCNNSKKGLKFTVSCGCSSEFVFVPYGST 315 Query: 344 IVVTDVAFLPEKGRGPELLGSHETALFSVAVDSRCQLHLLPSRR 387 I V V G +L H + S Q SR Sbjct: 316 IAVYTV----YSGEQITMLKGHYKTVDCCVFQSNFQELYSGSRD 355 Score = 35.5 bits (80), Expect = 0.039, Method: Composition-based stats. Identities = 27/205 (13%), Positives = 61/205 (29%), Gaps = 39/205 (19%) Query: 195 HEGEIEDLALGP-DGKL-VTVGRDLKASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRF 252 H G I L + P +G+ ++ G D ++ + S+ Y C+ Sbjct: 42 HGGGINTLDIEPVEGRYMLSGGSDGVIVLYDLEN---------------SSRQSYYTCKA 86 Query: 253 G-QVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVS-- 309 + + ++V+ +++D + + D + Sbjct: 87 VCSIGRDHPDVHRYSVETVQWYPHDTGMFTSSSFDKT--------------LKVWDTNTL 132 Query: 310 ESGTFLGLGTVTGSVAIYIAFSLQCLYYV-REAHGIVVTDVAFLPEKGRGPELLGSHETA 368 ++ S + + CL V + + D+ + G +L H Sbjct: 133 QTADVFNFEETVYSHHMSPVSTKHCLVAVGTRGPKVQLCDL----KSGSCSHILQGHRQE 188 Query: 369 LFSVAVDSRCQLHLLPSRRSVPVWL 393 + +V+ R L + V L Sbjct: 189 ILAVSWSPRYDYILATASADSRVKL 213 >3JB9-S nrPDB Length = 488 Score = 41.3 bits (95), Expect = 9e-04, Method: Composition-based stats. Identities = 15/66 (22%), Positives = 29/66 (43%), Gaps = 2/66 (3%) Query: 163 NHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK--LVTVGRDLKAS 220 + D L G +G +R ++ S ++ +F H ++ L G +G +VT D Sbjct: 342 HPDGNLFVAGLENGELRFFETSSGNELTKFGPHSSPVKTLQFGENGYWLVVTTNDDSDIF 401 Query: 221 VWQKDQ 226 +W + Sbjct: 402 IWDLRK 407 Score = 35.5 bits (80), Expect = 0.050, Method: Composition-based stats. Identities = 23/141 (16%), Positives = 47/141 (33%), Gaps = 14/141 (9%) Query: 144 LQAVQTDFSSDPLQKVVCF---NHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIE 200 LQ+V SS P+ + V F + L + ++ + S + H I Sbjct: 282 LQSVGEPTSSIPIDEKVNFLQAHPSGEYLLAAS-NEKCYIFSLKSQVYNITVAQH---IT 337 Query: 201 DLALGPDGKLVTVG-RDLKASVWQK---DQLVTQLHWQENGPTFSSTPYRYQACRFGQVP 256 LA+ PDG L G + + ++ ++L T Y Sbjct: 338 SLAVHPDGNLFVAGLENGELRFFETSSGNELTKFGPHSSPVKTLQFGENGYW---LVVTT 394 Query: 257 DQPAGLRLFTVQIPHKRLRQP 277 + + + ++ ++ + P Sbjct: 395 NDDSDIFIWDLRKSELVQKIP 415 >3W15-A nrPDB Length = 368 Score = 40.9 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 32/150 (21%), Positives = 54/150 (36%), Gaps = 25/150 (16%) Query: 156 LQKVVC-FNHDNTLL-ATGGTDGYVRVWKVP----------SLEKVLEF-KAHEGEIEDL 202 L+ + C FN + ATGG D +R+W + + + E AH I + Sbjct: 223 LEALTCDFNKYRPYVVATGGVDNAIRIWDIRMLNKNPGQLHNSSCINEIPNAHGLAIRKV 282 Query: 203 ALGPDGK--LVTVGRDLKASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPA 260 P L++ D+ +W + ++ +E T S+ + F Q + Sbjct: 283 TWSPHHSNILMSASYDMTCRIW---RDLSNDGAKETYKTNSTDATKGSIFNFTQHSE--- 336 Query: 261 GLRLFTVQIPHKRLRQPPPCYLTAWDGSNF 290 F +P TAWDG+ F Sbjct: 337 ----FVFGADWSLWGKPGYVASTAWDGNLF 362 Score = 37.0 bits (84), Expect = 0.014, Method: Composition-based stats. Identities = 35/223 (15%), Positives = 70/223 (31%), Gaps = 52/223 (23%) Query: 169 LATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQKDQLV 228 + DG +++W + + + L P +T D ++ K + Sbjct: 122 FLSSSWDGSIKIWSPLRKQSL------------MTLTPRPLEITKMVDPLNAIILKKKSF 169 Query: 229 TQLHWQEN-GPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWDG 287 T + N +P+ + LF +++P + + Sbjct: 170 TGISKNRNCVYQAQFSPHDQ---NLVLSCSGNSYASLFDIRLPSGKNQ------------ 214 Query: 288 SNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQ----------CLYY 337 +NFL G E ++C + G V ++ I+ L C+ Sbjct: 215 NNFL----VHSGLEALTCDFNKYRPYVVATGGVDNAIRIWDIRMLNKNPGQLHNSSCINE 270 Query: 338 VREAHGIVVTDVAFLPEKGRGPELLGSHETALFSVAVDSRCQL 380 + AHG+ + V + P H L S + D C++ Sbjct: 271 IPNAHGLAIRKVTWSPH----------HSNILMSASYDMTCRI 303 >5WLC-LN nrPDB Length = 776 Score = 40.5 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 28/67 (41%), Gaps = 1/67 (1%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDLK 218 V + +A+G + G ++ W FKAH+ ++ L D V + G D K Sbjct: 244 VIYLPRTDQIASGDSTGSIKFWDFQFATLNQSFKAHDADVLCLTTDTDNNYVFSAGVDRK 303 Query: 219 ASVWQKD 225 + ++ Sbjct: 304 IFQFSQN 310 Score = 31.2 bits (69), Expect = 0.74, Method: Composition-based stats. Identities = 21/137 (15%), Positives = 40/137 (29%), Gaps = 25/137 (18%) Query: 194 AHEGEIEDLALGPDGKLVTVGRDLKASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFG 253 +H+ I L D +L + +W P Sbjct: 52 SHKSNINKLTPS-DLRLAIGRSNGNIEIWN--------------------PRNNWFQEMV 90 Query: 254 QVPDQPAGLRLFTVQIPHKRLRQ----PPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVS 309 + + + + +T WD + LPLR C V+ + ++ Sbjct: 91 IEGGKDRSIEGLCWSNVNGESLRLFSIGGSTVVTEWDLATGLPLRNYDCNSGVIWSISIN 150 Query: 310 ESGTFLGLGTVTGSVAI 326 +S L +G G+V + Sbjct: 151 DSQDKLSVGCDNGTVVL 167 Score = 28.5 bits (62), Expect = 5.5, Method: Composition-based stats. Identities = 19/96 (19%), Positives = 37/96 (38%), Gaps = 11/96 (11%) Query: 154 DPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLE---------KVLEFKAHEGEIEDLAL 204 +P K V N + L+ + + V++W + + L K + I +L Sbjct: 376 EPYSKNVLVNKEQRLVVSWS-ESTVKIWTMGTDSSTEQNYKLVCKLTLK-DDQNISTCSL 433 Query: 205 GPDGKLVTVGRDLKASVWQKDQLVTQLHWQENGPTF 240 PDG+++ VGR V+ + +L + Sbjct: 434 SPDGQVLVVGRPSTTKVFHLQPVGNKLKVTKLDNDL 469 >5CXB-B nrPDB Length = 369 Score = 40.1 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 13/34 (38%), Positives = 18/34 (52%), Gaps = 1/34 (2%) Query: 192 FKAHEGEIEDLALGPDG-KLVTVGRDLKASVWQK 224 F+ HEG + +A+ P G L T G D VW+ Sbjct: 17 FRGHEGRVRSVAIDPTGVALATGGDDGTVRVWEL 50 Score = 32.8 bits (73), Expect = 0.27, Method: Composition-based stats. Identities = 15/48 (31%), Positives = 24/48 (50%), Gaps = 1/48 (2%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAH-EGEIEDLALGP 206 V + LATGG DG VRVW++ + +V K + + + + P Sbjct: 27 VAIDPTGVALATGGDDGTVRVWELLTGRQVWSVKLNGDEAVNTVRWRP 74 Score = 28.9 bits (63), Expect = 4.2, Method: Composition-based stats. Identities = 31/180 (17%), Positives = 60/180 (33%), Gaps = 20/180 (11%) Query: 156 LQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGR 215 L + F+ L +R + + LE V + I + P G + VG Sbjct: 203 LAQTASFHPLRPLFFVATQ-RSIRCYDLQKLELVKIVQPGAKWISSFDVHPGGDNLVVGS 261 Query: 216 DLKASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQ--PAGLRLFTVQIPHKR 273 K +W L + + T + R+ D L++F ++P+ + Sbjct: 262 YDKRLLWHDLDLSNRPYKTMRFHTEAIRAVRFHKGGLPLFADASDDGSLQIFHGKVPNDQ 321 Query: 274 LRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCL-----DVSESGTFLGLGTVTGSVAIYI 328 L P +P++ GH+VV+ L D + G+ +++ Sbjct: 322 LENP-----------TIVPVKMLK-GHKVVNKLGVLDIDWHPREPWCVSAGADGTARLWM 369 >5A9Q-7 nrPDB Length = 360 Score = 39.7 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 34/170 (20%), Positives = 52/170 (30%), Gaps = 11/170 (6%) Query: 195 HEGEIEDLALGPDGK-LVTVGRDLKASVWQKDQLVTQLHWQENGPTFSSTPYR--YQACR 251 H+ I D++ G+ + T D VW K + H + T S + +R + Sbjct: 11 HKDLIHDVSFDFHGRRMATCSSDQSVKVWDKSES-GDWHCTASWKTHSGSVWRVTWAHPE 69 Query: 252 FGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSES 311 FGQV + R V + W L S Sbjct: 70 FGQVLASCSFDRTAAVWEEIVGESNDKLRGQSHWVKRTTL---VDSRTSVTDVKFAPKHM 126 Query: 312 GTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGI----VVTDVAFLPEKGR 357 G L + G V IY A + L H I + +++ P R Sbjct: 127 GLMLATCSADGIVRIYEAPDVMNLSQWSLQHEISCKLSCSCISWNPSSSR 176 Score = 38.6 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 22/86 (25%), Positives = 35/86 (40%), Gaps = 12/86 (13%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVP---SLEKVLEFKAHEGEIEDLALG-PD--GKLVTV 213 V F+ +AT +D V+VW +K H G + + P+ L + Sbjct: 18 VSFDFHGRRMATCSSDQSVKVWDKSESGDWHCTASWKTHSGSVWRVTWAHPEFGQVLASC 77 Query: 214 GRDLKASVWQK------DQLVTQLHW 233 D A+VW++ D+L Q HW Sbjct: 78 SFDRTAAVWEEIVGESNDKLRGQSHW 103 Score = 36.6 bits (83), Expect = 0.021, Method: Composition-based stats. Identities = 28/192 (14%), Positives = 62/192 (32%), Gaps = 35/192 (18%) Query: 164 HDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEG-----EIEDLALGPDGK------LVT 212 H +LAT DG VR+++ P + + ++ ++ P + Sbjct: 125 HMGLMLATCSADGIVRIYEAPDVMNLSQWSLQHEISCKLSCSCISWNPSSSRAHSPMIAV 184 Query: 213 VGRDL------KASVWQKDQ-------LVTQLHWQENGPTFSSTPYRYQACRFGQVPDQP 259 D K +++ ++ T + + + P + F + Sbjct: 185 GSDDSSPNAMAKVQIFEYNENTRKYAKAETLMTVTDPVHDIAFAPNLGR--SFHILAIAT 242 Query: 260 AGLRLFTVQIPHKRLRQP--PPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGL 317 +R+FT++ K L P + + + + +V + +GT L Sbjct: 243 KDVRIFTLKPVRKELTSSGGPTKFEIH------IVAQFDNHNSQVWRV-SWNITGTVLAS 295 Query: 318 GTVTGSVAIYIA 329 G V ++ A Sbjct: 296 SGDDGCVRLWKA 307 Score = 35.1 bits (79), Expect = 0.057, Method: Composition-based stats. Identities = 12/84 (14%), Positives = 24/84 (28%), Gaps = 15/84 (17%) Query: 166 NTLLATGGTDGYVRVWKVPSLEKVLEFKAHE------------GEIEDLALGPDG---KL 210 +LA+ D VW+ E + + + D+ P L Sbjct: 71 GQVLASCSFDRTAAVWEEIVGESNDKLRGQSHWVKRTTLVDSRTSVTDVKFAPKHMGLML 130 Query: 211 VTVGRDLKASVWQKDQLVTQLHWQ 234 T D +++ ++ W Sbjct: 131 ATCSADGIVRIYEAPDVMNLSQWS 154 Score = 29.3 bits (64), Expect = 3.1, Method: Composition-based stats. Identities = 8/39 (20%), Positives = 17/39 (43%), Gaps = 1/39 (2%) Query: 188 KVLEFKAHEGEIEDLALGPDGK-LVTVGRDLKASVWQKD 225 V +F H ++ ++ G L + G D +W+ + Sbjct: 270 IVAQFDNHNSQVWRVSWNITGTVLASSGDDGCVRLWKAN 308 >2P9P-C nrPDB Length = 372 Score = 39.7 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 37/227 (16%), Positives = 71/227 (31%), Gaps = 52/227 (22%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLE--KVLEFKAHEGEIEDLALGPDG-KLVTVGRDLK 218 +N D T +A + V +++ + +V E K H G++ + PD ++VT G D Sbjct: 16 WNKDRTQIAICPNNHEVHIYEKSGNKWVQVHELKEHNGQVTGVDWAPDSNRIVTCGTDRN 75 Query: 219 ASVWQK--------------DQLVTQLHWQENGPTFSSTP-------------YRYQACR 251 A VW ++ + W N F+ + C+ Sbjct: 76 AYVWTLKGRTWKPTLVILRINRAARCVRWAPNEKKFAVGSGSRVISICYFEQENDWWVCK 135 Query: 252 FGQVP--------------------DQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFL 291 + P R+F+ I R P + + + Sbjct: 136 HIKKPIRSTVLSLDWHPNSVLLAAGSCDFKCRIFSAYIKEVEERPAPTPWGSKMPFGELM 195 Query: 292 PLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYV 338 + SCG C S +G+ + + +V + A + + Sbjct: 196 FESSSSCGWVHGVCF--SANGSRVAWVSHDSTVCLADADKKMAVATL 240 >3I2N-A nrPDB Length = 357 Score = 38.6 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 47/247 (19%), Positives = 82/247 (33%), Gaps = 49/247 (19%) Query: 131 ETQHEGLEL--RVENLQAVQT-DFSSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLE 187 E QH L+L +E + ++ F + LQ+ LATG G + +W + + E Sbjct: 50 EIQHGDLKLLREIEKAKPIKCGTFGATSLQQ--------RYLATGDFGGNLHIWNLEAPE 101 Query: 188 K-VLEFKAHEGEIEDLALGPDG-------KLVTVGRDLKASVWQKDQLVTQLHWQENGP- 238 V K H+ I + ++VT RD VW Q + E Sbjct: 102 MPVYSVKGHKEIINAIDGIGGLGIGEGAPEIVTGSRDGTVKVWDPRQKDDPVANMEPVQG 161 Query: 239 -------TFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFL 291 T + Q R ++LF ++ W+ + Sbjct: 162 ENKRDCWTVAFGNAYNQEERVVCAGYDNGDIKLFDLRN-----------MALRWETN--- 207 Query: 292 PLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSL---QCLYYVRE-AHGIVVT 347 ++ C E D+S + + ++ G ++ + + V E AH V Sbjct: 208 -IKNGVCSLEFDRK-DISMN-KLVAT-SLEGKFHVFDMRTQHPTKGFASVSEKAHKSTVW 263 Query: 348 DVAFLPE 354 V LP+ Sbjct: 264 QVRHLPQ 270 >5WLC-LH nrPDB Length = 896 Score = 38.6 bits (88), Expect = 0.006, Method: Composition-based stats. Identities = 19/91 (20%), Positives = 38/91 (41%), Gaps = 9/91 (9%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVT--------- 212 F+HD + L +GG + + +W++ + + + + I+ LGP G + Sbjct: 305 FSHDGSYLLSGGWEKVMSLWQLETNSQQFLPRLNGIIIDCQVLGPQGNYYSLILQMTENN 364 Query: 213 VGRDLKASVWQKDQLVTQLHWQENGPTFSST 243 D + + L ++L P F+ST Sbjct: 365 SNSDYQFLLLNASDLTSKLSINGPLPVFNST 395 Score = 35.9 bits (81), Expect = 0.034, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 30/67 (44%), Gaps = 2/67 (2%) Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK-LVTVGRDLK 218 + ++ LA G G + + + L+ + K H + L+ DG L++ G + Sbjct: 262 MAIDNMGQQLAVGFASGVISIVSLADLQ-IRLLKWHIDSVLSLSFSHDGSYLLSGGWEKV 320 Query: 219 ASVWQKD 225 S+WQ + Sbjct: 321 MSLWQLE 327 >5WLC-LW nrPDB Length = 554 Score = 38.2 bits (87), Expect = 0.007, Method: Composition-based stats. Identities = 20/78 (25%), Positives = 35/78 (44%), Gaps = 2/78 (2%) Query: 163 NHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKL-VTVGRDLKASV 221 N N ++ G ++G V +W E +++ + G + +A+ G T G D + Sbjct: 241 NPWNAVMHLGHSNGTVSLWSPSMPEPLVKLLSARGPVNSIAIDRSGYYMATTGADRSMKI 300 Query: 222 WQKDQLVTQLHWQENGPT 239 W + QLH E+ PT Sbjct: 301 WDI-RNFKQLHSVESLPT 317 Score = 38.2 bits (87), Expect = 0.007, Method: Composition-based stats. Identities = 10/76 (13%), Positives = 35/76 (46%), Gaps = 2/76 (2%) Query: 155 PLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVG 214 P+ + + +AT G D +++W + + +++ ++ ++++ D L+ + Sbjct: 276 PVNSI-AIDRSGYYMATTGADRSMKIWDIRNFKQLHSVESLPTPGTNVSIS-DTGLLALS 333 Query: 215 RDLKASVWQKDQLVTQ 230 R ++W+ ++ Sbjct: 334 RGPHVTLWKDALKLSG 349 >5A9Q-2 nrPDB Length = 326 Score = 37.8 bits (86), Expect = 0.009, Method: Composition-based stats. Identities = 21/151 (13%), Positives = 46/151 (30%), Gaps = 13/151 (8%) Query: 169 LATGGTDGYVRVW--KVPSLEKVLEFKAHEGEIEDLALGPD--GKLVTVGRDLKASVWQK 224 T D +R++ + + + H I L P ++ +V D +W Sbjct: 95 FCTSAADMKIRLFTSDLQDKNEYKVLEGHTDFINGLVFDPKEGQEIASVSDDHTCRIWNL 154 Query: 225 DQLVTQLHW-QENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRL---RQPPPC 280 + + T G + P V ++ +R + + L + P Sbjct: 155 EGVQTAHFVLHSPGMSVCWHPEETFK---LMVAEKNGTIRFYDLLAQQAILSLESEQVPL 211 Query: 281 YLTAWDGSNFLPLRTKSCGHEVVSCLDVSES 311 W N + + ++ D++ S Sbjct: 212 MSAHWCLKNTFKVGAVAGNDWLI--WDITRS 240 Score = 30.5 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 24/151 (15%), Positives = 48/151 (31%), Gaps = 33/151 (21%) Query: 234 QENGPTFSSTPYRY---QACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNF 290 ++G + Y C F + G++ T++ H +R AW Sbjct: 30 GDSGNLIAYGGNNYVVIGTCTFQEEEADVEGIQYKTLRTFHHGVRVD----GIAWSPET- 84 Query: 291 LPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIA-FSLQCLYYVREAHGIVVTDV 349 R S + C + ++ + + Y V E H + + Sbjct: 85 ---RLDSLPPVIKFC-----------TSAADMKIRLFTSDLQDKNEYKVLEGHTDFINGL 130 Query: 350 AFLPEKGRGPELLGSHETALFSVAVDSRCQL 380 F P++G+ + SV+ D C++ Sbjct: 131 VFDPKEGQ----------EIASVSDDHTCRI 151 >5A31-R nrPDB Length = 386 Score = 37.8 bits (86), Expect = 0.010, Method: Composition-based stats. Identities = 32/249 (12%), Positives = 68/249 (27%), Gaps = 28/249 (11%) Query: 166 NTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKAS----- 220 + LA G +G V ++ V + + H + L+ + L + RD + Sbjct: 143 GSHLAVGQANGLVEIYDVMKRKCIRTLSGHIDRVACLSWN-NHVLTSGSRDHRILHRDVR 201 Query: 221 --------VWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHK 272 + Q V L W +S + + F Sbjct: 202 MPDPFFETIESHTQEVCGLKWNVADNKLASGGN--DNVVHVYEGTSKSPILTFDEHKAAV 259 Query: 273 RLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSL 332 + AW S + G L + T + + + I Sbjct: 260 K--------AMAW--SPHKRGVLATGGGTADRRLKIWNVNTSIKMSDIDSGSQICNMVWS 309 Query: 333 QCLYYVREAHGIVVTDVAFLPEKGRGP-ELLGSHETALFSVAVDSRCQLHLLPS-RRSVP 390 + + +HG ++ P +L H + + + + + + ++ Sbjct: 310 KNTNELVTSHGYSKYNLTLWDCNSMDPIAILKGHSFRVLHLTLSNDGTTVVSGAGDETLR 369 Query: 391 VWLLLLLCV 399 W L + V Sbjct: 370 YWKLFDVSV 378 >4BH6-A nrPDB Length = 308 Score = 37.8 bits (86), Expect = 0.010, Method: Composition-based stats. Identities = 31/245 (12%), Positives = 66/245 (26%), Gaps = 28/245 (11%) Query: 166 NTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKAS----- 220 + LA G +G V ++ V + + H + L+ + L + RD + Sbjct: 74 GSHLAVGQANGLVEIYDVMKRKCIRTLSGHIDRVACLSWN-NHVLTSGSRDHRILHRDVR 132 Query: 221 --------VWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHK 272 + Q V L W +S + + F Sbjct: 133 MPDPFFETIESHTQEVCGLKWNVADNKLASGGN--DNVVHVYEGTSKSPILTFDEHKAAV 190 Query: 273 RLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSL 332 + AW S + G L + T + + + I Sbjct: 191 K--------AMAW--SPHKRGVLATGGGTADRRLKIWNVNTSIKMSDIDSGSQICNMVWS 240 Query: 333 QCLYYVREAHGIVVTDVAFLPEKGRGP-ELLGSHETALFSVAVDSRCQLHLLPS-RRSVP 390 + + +HG ++ P +L H + + + + + + ++ Sbjct: 241 KNTNELVTSHGYSKYNLTLWDCNSMDPIAILKGHSFRVLHLTLSNDGTTVVSGAGDETLR 300 Query: 391 VWLLL 395 W L Sbjct: 301 YWKLF 305 >5MC6-j nrPDB Length = 397 Score = 37.4 bits (85), Expect = 0.011, Method: Composition-based stats. Identities = 17/64 (26%), Positives = 28/64 (43%) Query: 137 LELRVENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHE 196 L + + QA +F+ + FN L + G DG +R W V + E++ H Sbjct: 274 LSVPTHSSQASLGEFAHSSWVMSLSFNDSGETLCSAGWDGKLRFWDVKTKERITTLNMHC 333 Query: 197 GEIE 200 +IE Sbjct: 334 DDIE 337 Score = 34.7 bits (78), Expect = 0.080, Method: Composition-based stats. Identities = 12/48 (25%), Positives = 21/48 (43%), Gaps = 5/48 (10%) Query: 194 AHEGEIEDLALGPDGK-LVTVGRDLKASVWQ---KDQLVTQ-LHWQEN 236 AH + L+ G+ L + G D K W K+++ T +H + Sbjct: 289 AHSSWVMSLSFNDSGETLCSAGWDGKLRFWDVKTKERITTLNMHCDDI 336 Score = 33.5 bits (75), Expect = 0.17, Method: Composition-based stats. Identities = 13/56 (23%), Positives = 27/56 (48%), Gaps = 6/56 (10%) Query: 168 LLATGGTDGYVRVWKVPSLEKVLEFKA------HEGEIEDLALGPDGKLVTVGRDL 217 L+ATG +G V++ ++ +L + F++ + I + P G L+ + D Sbjct: 199 LIATGFNNGTVQISELSTLRPLYNFESQHSMINNSNSIRSVKFSPQGSLLAIAHDS 254 >6EM1-m nrPDB Length = 807 Score = 36.6 bits (83), Expect = 0.022, Method: Composition-based stats. Identities = 15/53 (28%), Positives = 23/53 (43%), Gaps = 6/53 (11%) Query: 163 NHDNTLLATGGTDGYVRVWKVPSLEKVLEF------KAHEGEIEDLALGPDGK 209 + LATG DG VRVW++ + +V + + IE + PD Sbjct: 446 DPSGLWLATGSDDGTVRVWEILTGREVYRTTLIDDEENPDYHIECIEWNPDAN 498 Score = 35.9 bits (81), Expect = 0.037, Method: Composition-based stats. Identities = 10/38 (26%), Positives = 17/38 (44%), Gaps = 1/38 (2%) Query: 187 EKVLEFKAHEGEIEDLALGPDGK-LVTVGRDLKASVWQ 223 + H+G++ L++ P G L T D VW+ Sbjct: 428 RCSTIYAGHKGKVRTLSIDPSGLWLATGSDDGTVRVWE 465 >6CB1-s nrPDB Length = 569 Score = 36.6 bits (83), Expect = 0.022, Method: Composition-based stats. Identities = 15/53 (28%), Positives = 23/53 (43%), Gaps = 6/53 (11%) Query: 163 NHDNTLLATGGTDGYVRVWKVPSLEKVLEF------KAHEGEIEDLALGPDGK 209 + LATG DG VRVW++ + +V + + IE + PD Sbjct: 208 DPSGLWLATGSDDGTVRVWEILTGREVYRTTLIDDEENPDYHIECIEWNPDAN 260 Score = 35.9 bits (81), Expect = 0.037, Method: Composition-based stats. Identities = 10/38 (26%), Positives = 17/38 (44%), Gaps = 1/38 (2%) Query: 187 EKVLEFKAHEGEIEDLALGPDGK-LVTVGRDLKASVWQ 223 + H+G++ L++ P G L T D VW+ Sbjct: 190 RCSTIYAGHKGKVRTLSIDPSGLWLATGSDDGTVRVWE 227 >6C0F-s nrPDB Length = 807 Score = 36.6 bits (83), Expect = 0.022, Method: Composition-based stats. Identities = 15/53 (28%), Positives = 23/53 (43%), Gaps = 6/53 (11%) Query: 163 NHDNTLLATGGTDGYVRVWKVPSLEKVLEF------KAHEGEIEDLALGPDGK 209 + LATG DG VRVW++ + +V + + IE + PD Sbjct: 446 DPSGLWLATGSDDGTVRVWEILTGREVYRTTLIDDEENPDYHIECIEWNPDAN 498 Score = 35.9 bits (81), Expect = 0.037, Method: Composition-based stats. Identities = 10/38 (26%), Positives = 17/38 (44%), Gaps = 1/38 (2%) Query: 187 EKVLEFKAHEGEIEDLALGPDGK-LVTVGRDLKASVWQ 223 + H+G++ L++ P G L T D VW+ Sbjct: 428 RCSTIYAGHKGKVRTLSIDPSGLWLATGSDDGTVRVWE 465 >1PI6-A nrPDB Length = 615 Score = 35.9 bits (81), Expect = 0.033, Method: Composition-based stats. Identities = 34/242 (14%), Positives = 77/242 (31%), Gaps = 33/242 (13%) Query: 165 DNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIED----LALGPDGKLVTVGRDLKAS 220 D+ AT G D +RVW V + + V ++ + ++ + + +G+++++ D + Sbjct: 263 DSQKFATVGADATIRVWDVTTSKCVQKWTLDKQQLGNQQVGVVATGNGRIISLSLDGTLN 322 Query: 221 VWQKDQ---LVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHK----- 272 ++ L T + + P + ++ H+ Sbjct: 323 FYELGHDEVLKTISGHNKGITALTVNP--------LISGSYDGRIMEWSSSSMHQDHSNL 374 Query: 273 ----RLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYI 328 + +WD + + TK + G F + T + I Sbjct: 375 IVSLDNSKAQEYSSISWDDTLKVNGITKHEFGSQPKVASANNDG-FTAVLTNDDDLLILQ 433 Query: 329 AFSLQCLYYVREAHGIVVTDVAFLPEKGRGPELLGSHETALF-----SVAVDSRCQLHLL 383 +F+ + VR ++ + L + +F V+ D + L Sbjct: 434 SFTGDIIKSVRLNSPGSAVSLS---QNYVAVGLEEGNTIQVFKLSDLEVSFDLKTPLRAK 490 Query: 384 PS 385 PS Sbjct: 491 PS 492 Score = 34.7 bits (78), Expect = 0.084, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 27/67 (40%), Gaps = 5/67 (7%) Query: 162 FNHDN-TLLATGGTDGYVRVWKVPSLEKVLEFKAHE----GEIEDLALGPDGKLVTVGRD 216 F+ D+ + T G+D + + S E + + + G I L+ K TVG D Sbjct: 214 FSPDSGEFVITVGSDRKISCFDGKSGEFLKYIEDDQEPVQGGIFALSWLDSQKFATVGAD 273 Query: 217 LKASVWQ 223 VW Sbjct: 274 ATIRVWD 280 Score = 34.3 bits (77), Expect = 0.11, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 25/58 (43%), Gaps = 1/58 (1%) Query: 167 TLLATGGTDGYVRVWKVPS-LEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQ 223 L+ATG D + ++ V ++ + AH+ + +L LV+ G D W Sbjct: 554 DLVATGSLDTNIFIYSVKRPMKIIKALNAHKDGVNNLLWETPSTLVSSGADACIKRWN 611 >4E5Z-B nrPDB Length = 436 Score = 35.9 bits (81), Expect = 0.034, Method: Composition-based stats. Identities = 26/160 (16%), Positives = 47/160 (29%), Gaps = 15/160 (9%) Query: 168 LLATGGTDGYVRVWKVPSLEKVLEF---KAHEGEIEDLALGPDG-KLVTVGRDLKASVWQ 223 LAT D V++W + + F H + PDG +L+T + + V+ Sbjct: 265 FLATASVDQTVKIWDLRQVRGKASFLYSLPHRHPVNAACFSPDGARLLTTDQKSEIRVYS 324 Query: 224 KDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLT 283 Q W +Q + P + + P + P L Sbjct: 325 ASQ------WDCPLGLIPHPHRHFQHLTPIKAAWHPRYNLIVVGRYPDPNFKSCTPYELR 378 Query: 284 A---WDGSNFL--PLRTKSCGHEVVSCLDVSESGTFLGLG 318 +DG++ + S + + G L Sbjct: 379 TIDVFDGNSGKMMCQLYDPESSGISSLNEFNPMGDTLASA 418 >1EJI-A nrPDB Length = 478 Score = 35.5 bits (80), Expect = 0.040, Method: Composition-based stats. Identities = 35/149 (23%), Positives = 52/149 (34%), Gaps = 13/149 (8%) Query: 118 RKGAAPAEKKCGAETQHEGLELRVENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGY 177 RKG + K G ET +E LE + + AV P NH +A Sbjct: 264 RKGVRSVDPKTGKETYYE-LESLINS--AVFPGLQGGP------HNHAIAGVAVALKQAM 314 Query: 178 VRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQKDQLVTQLHWQENG 237 +K+ L+ + +A + +L K+VT G D + T E Sbjct: 315 TTEFKIYQLQVLANCRALSDALTELGY----KIVTGGSDNHLILMDLRSKGTDGGRAEKV 370 Query: 238 PTFSSTPYRYQACRFGQVPDQPAGLRLFT 266 S C + +P+GLRL T Sbjct: 371 LEACSIACNKNTCPGDKSALRPSGLRLGT 399 >6F1U-h nrPDB Length = 612 Score = 35.5 bits (80), Expect = 0.046, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 26/67 (38%), Gaps = 5/67 (7%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKAS- 220 F+H L T D V++W + + + F+ + G + D+ P + D Sbjct: 467 FSH---LFVTSSFDWTVKLWSTKNNKPLYSFEDNAGYVYDVMWSPTHPALFACVDGMGRL 523 Query: 221 -VWQKDQ 226 +W + Sbjct: 524 DLWNLNN 530 >2I3T-A nrPDB Length = 341 Score = 35.5 bits (80), Expect = 0.048, Method: Composition-based stats. Identities = 13/90 (14%), Positives = 29/90 (32%), Gaps = 10/90 (11%) Query: 155 PLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVG 214 P+ + F+ + L T G+DG + W + + +K+ F D + Sbjct: 253 PVNSIE-FSPRHKFLYTAGSDGIISCWNLQTRKKIKNF---------AKFNEDSVVKIAC 302 Query: 215 RDLKASVWQKDQLVTQLHWQENGPTFSSTP 244 D + D + +++ Sbjct: 303 SDNILCLATSDDTFKTNAAIDQTIELNASS 332 >2PM9-A nrPDB Length = 416 Score = 34.7 bits (78), Expect = 0.078, Method: Composition-based stats. Identities = 19/88 (21%), Positives = 28/88 (31%), Gaps = 2/88 (2%) Query: 163 NHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK--LVTVGRDLKAS 220 + D LL + G D V +W S E++ +F A P+ D K Sbjct: 272 HQDEHLLLSSGRDNTVLLWNPESAEQLSQFPARGNWCFKTKFAPEAPDLFACASFDNKIE 331 Query: 221 VWQKDQLVTQLHWQENGPTFSSTPYRYQ 248 V L L QE + + Sbjct: 332 VQTLQNLTNTLDEQETETKQQESETDFW 359 Score = 34.3 bits (77), Expect = 0.11, Method: Composition-based stats. Identities = 10/77 (12%), Positives = 31/77 (40%), Gaps = 7/77 (9%) Query: 156 LQKVVCFNHDNTLLATGGTDGYVRVWKV--PSLEK--VLEFKAHEGEIEDLALGP--DGK 209 + ++H+N ++A +G + ++ + + F H ++ + D Sbjct: 70 FNDLD-WSHNNKIIAGALDNGSLELYSTNEANNAINSMARFSNHSSSVKTVKFNAKQDNV 128 Query: 210 LVTVGRDLKASVWQKDQ 226 L + G + + +W ++ Sbjct: 129 LASGGNNGEIFIWDMNK 145 Score = 30.9 bits (68), Expect = 1.0, Method: Composition-based stats. Identities = 18/112 (16%), Positives = 38/112 (33%), Gaps = 7/112 (6%) Query: 165 DNTLLATG---GTDGYVRVWKV--PSLEKVLEFKAHEGEIEDLALGPDGK--LVTVGRDL 217 ++T +AT D + +W + + + H+ I L + L++ GRD Sbjct: 226 NSTRVATATGSDNDPSILIWDLRNANTPLQTLNQGHQKGILSLDWCHQDEHLLLSSGRDN 285 Query: 218 KASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQI 269 +W + + G T + +A + + T+Q Sbjct: 286 TVLLWNPESAEQLSQFPARGNWCFKTKFAPEAPDLFACASFDNKIEVQTLQN 337 >5LTD-A nrPDB Length = 525 Score = 34.3 bits (77), Expect = 0.10, Method: Composition-based stats. Identities = 17/59 (28%), Positives = 28/59 (47%), Gaps = 3/59 (5%) Query: 160 VCFNHDNTLLATGGTDGYV-RVWKVPSLEKVLEFK--AHEGEIEDLALGPDGKLVTVGR 215 + + D LLAT G + RV+ V + K+ +F+ + +I LA PD + V Sbjct: 228 IALSKDGLLLATASDKGTIIRVFSVATGIKLYQFRRGTYPTKIYSLAFSPDNRFVIASS 286 Score = 29.3 bits (64), Expect = 2.9, Method: Composition-based stats. Identities = 11/47 (23%), Positives = 21/47 (44%) Query: 175 DGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASV 221 +G V ++ +L+ +AH + +AL DG L+ D + Sbjct: 201 NGDVIIFDAKTLQPTSVIEAHRTSLAAIALSKDGLLLATASDKGTII 247 >6IYY-A nrPDB Length = 317 Score = 33.5 bits (75), Expect = 0.17, Method: Composition-based stats. Identities = 27/121 (22%), Positives = 49/121 (40%), Gaps = 7/121 (5%) Query: 159 VVCFNHDNTLLA-TGGTDGYVRVWKVPSLEKV-LEFKAHEGEIEDLALGPDG-KLVTVGR 215 V+C N +N+LLA G G+V++ + S EK ++ AHEG + +AL G ++ T Sbjct: 137 VLCPNSNNSLLAFPGTHTGHVQLVDLASTEKPPVDIPAHEGVLSCIALNLQGTRIATASE 196 Query: 216 DLKA-SVWQ--KDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHK 272 ++ L+ +L + A V + +F + P Sbjct: 197 KGTLIRIFDTSSGHLIQELRRGSQAANIYCINFNQDA-SLICVSSDHGTVHIFAAEDPKS 255 Query: 273 R 273 + Sbjct: 256 K 256 >3DW8-B nrPDB Length = 447 Score = 33.5 bits (75), Expect = 0.19, Method: Composition-based stats. Identities = 22/107 (20%), Positives = 37/107 (34%), Gaps = 26/107 (24%) Query: 146 AVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVL-----------EFKA 194 AV D + + V FNH LLATG G V +++ K+ F++ Sbjct: 20 AVDDDVAEADIISTVEFNHSGELLATGDKGGRVVIFQQEQENKIQSHSRGEYNVYSTFQS 79 Query: 195 H------------EGEIEDLALGPD---GKLVTVGRDLKASVWQKDQ 226 H E +I + P + + D +W+ + Sbjct: 80 HEPEFDYLKSLEIEEKINKIRWLPQKNAAQFLLSTNDKTIKLWKISE 126 Score = 28.9 bits (63), Expect = 3.9, Method: Composition-based stats. Identities = 15/99 (15%), Positives = 35/99 (35%), Gaps = 13/99 (13%) Query: 194 AHEGEIEDLALGPDGKLVTVGRDLKASVWQK---DQLVTQL-----HWQENGPTFSSTPY 245 AH I +++ D + DL+ ++W D+ + + +E ++ + Sbjct: 175 AHTYHINSISINSDYETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEF 234 Query: 246 RYQACRFGQVPDQPAGLRLFTVQIP-----HKRLRQPPP 279 +C +RL ++ H +L + P Sbjct: 235 HPNSCNTFVYSSSKGTIRLCDMRASALCDRHSKLFEEPE 273 >3F3P-A nrPDB Length = 351 Score = 33.5 bits (75), Expect = 0.19, Method: Composition-based stats. Identities = 27/181 (14%), Positives = 53/181 (29%), Gaps = 25/181 (13%) Query: 166 NTLLATGGTDGYVRVW---------KVPSLEKVLEFKAHEGEIEDLALGPDG---KLVTV 213 ++A+ D V++W K+ +G + + P KL + Sbjct: 71 GRIIASASYDKTVKLWEEDPDQEECSGRRWNKLCTLNDSKGSLYSVKFAPAHLGLKLACL 130 Query: 214 GRDLKASVWQKDQLVTQLHW--QENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPH 271 G D ++ + W S P + F F+ + Sbjct: 131 GNDGILRLYDALEPSDLRSWTLTSEMKVLSIPPANHLQSDFCLSWCPSR----FSPEKLA 186 Query: 272 KRLRQPPPCYLTAWDGSNFLPLRTKSCGHE-VVSCLDVSES----GTFLGLGTVTGSVAI 326 + Y DG L + K GH+ ++ + + S + G G + I Sbjct: 187 VSALEQAIIYQRGKDGK--LHVAAKLPGHKSLIRSISWAPSIGRWYQLIATGCKDGRIRI 244 Query: 327 Y 327 + Sbjct: 245 F 245 Score = 33.2 bits (74), Expect = 0.24, Method: Composition-based stats. Identities = 10/39 (25%), Positives = 19/39 (48%), Gaps = 1/39 (2%) Query: 187 EKVLEFKAHEGEIEDLALGPDGKLVTV-GRDLKASVWQK 224 E + E H GE+ ++ G +++ G D K +W+ Sbjct: 297 ELLSEHDDHNGEVWSVSWNLTGTILSSAGDDGKVRLWKA 335 >5AJA-A nrPDB Length = 361 Score = 33.2 bits (74), Expect = 0.20, Method: Composition-based stats. Identities = 20/127 (15%), Positives = 39/127 (30%), Gaps = 8/127 (6%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVG---RDLK 218 F+ L G G ++++ V S ++ + H I L DG L+ Sbjct: 45 FSARERFLMLGTCTGQLKLYNVFSGQEEASYNCHNSAITHLEPSRDGSLLLTSATWSQPL 104 Query: 219 ASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQ-----VPDQPAGLRLFTVQIPHKR 273 +++W + H + + + + D G +L T+ P Sbjct: 105 SALWGMKSVFDMKHSFTEDHYVEFSKHSQDRVIGTKGDIAHIYDIQTGNKLLTLFNPDLA 164 Query: 274 LRQPPPC 280 C Sbjct: 165 NNYKRNC 171 >5WLC-LS nrPDB Length = 594 Score = 31.2 bits (69), Expect = 0.89, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 31/70 (44%), Gaps = 6/70 (8%) Query: 162 FNHDNTL--LATGGTDGYVRVWKVPSLEKVLEFKAHE---GEIEDLALGPDGKLVTVGRD 216 F+ D + +A+ +R+ +PS + G++ +A P G L+ VG + Sbjct: 523 FSPDGQILCMASRAVKDALRLVHLPSCSVFSNWPTSGTPLGKVTSVAFSPSGGLLAVGNE 582 Query: 217 -LKASVWQKD 225 K +W+ + Sbjct: 583 QGKVRLWKLN 592 Score = 29.7 bits (65), Expect = 2.4, Method: Composition-based stats. Identities = 16/34 (47%), Positives = 19/34 (55%), Gaps = 2/34 (5%) Query: 152 SSDPLQKV--VCFNHDNTLLATGGTDGYVRVWKV 183 S PL KV V F+ LLA G G VR+WK+ Sbjct: 558 SGTPLGKVTSVAFSPSGGLLAVGNEQGKVRLWKL 591 Score = 28.9 bits (63), Expect = 4.5, Method: Composition-based stats. Identities = 14/71 (19%), Positives = 22/71 (30%), Gaps = 8/71 (11%) Query: 162 FNHDNTLLATGGTDGYVRVWKV--PSLEKVLEFKAHEGEIEDLAL------GPDGKLVTV 213 F+ LL TGG D +R++ + + V I+ + T Sbjct: 256 FHPSKPLLLTGGYDKTLRIYHIDGKTNHLVTSLHLVGSPIQTCTFYTSLSNQNQQNIFTA 315 Query: 214 GRDLKASVWQK 224 GR W Sbjct: 316 GRRRYMHSWDL 326 >5BPW-A nrPDB Length = 843 Score = 30.9 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 19/85 (22%), Positives = 35/85 (41%), Gaps = 5/85 (5%) Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEG---EIEDLALGPDGKLV--TVGRD 216 ++ L+A T G V + ++ S +V F +E E+ LA PDGKL+ + Sbjct: 28 WSPKRDLIALANTAGEVLLHRLASFHRVWSFPPNENTGKEVTCLAWRPDGKLLAFALADT 87 Query: 217 LKASVWQKDQLVTQLHWQENGPTFS 241 K + ++ + + P Sbjct: 88 KKIVLCDVEKPESLHSFSVEAPVSC 112 >2VDU-B nrPDB Length = 450 Score = 30.5 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 12/58 (20%), Positives = 23/58 (39%), Gaps = 1/58 (1%) Query: 167 TLLATGGTDGYVRVWKVPSLEKVLE-FKAHEGEIEDLALGPDGKLVTVGRDLKASVWQ 223 + T D ++++ P V + H+ + + G D L++ G D K W Sbjct: 211 QFIITSDRDEHIKISHYPQCFIVDKWLFGHKHFVSSICCGKDYLLLSAGGDDKIFAWD 268 >4V0N-B nrPDB Length = 425 Score = 29.7 bits (65), Expect = 2.6, Method: Composition-based stats. Identities = 14/65 (21%), Positives = 23/65 (35%), Gaps = 2/65 (3%) Query: 180 VWKVPSLEKVLEFKAHEGEIEDLALGPDG--KLVTVGRDLKASVWQKDQLVTQLHWQENG 237 VW + V A+ + L DG +LV D K +W+ Q ++ + Sbjct: 39 VWLDAFNDPVAGISAYTPCVHTCNLFGDGENRLVIADEDRKLKIWKGTQKASEHPLLDTP 98 Query: 238 PTFSS 242 S Sbjct: 99 VAICS 103 >2X86-A nrPDB Length = 357 Score = 29.7 bits (65), Expect = 2.7, Method: Composition-based stats. Identities = 13/60 (21%), Positives = 21/60 (35%), Gaps = 4/60 (6%) Query: 335 LYYVREAHGIVVTDVAFLPEKGRGPELLGSHETALFSVAVDSRCQLHLLPSRRSVPVWLL 394 +Y RE H + VAF +L LF + + + + V +W L Sbjct: 217 VYGPREGHKGSMASVAFHLNT----QLNNGESPKLFEGSENFKRDFVYVGDVADVNLWFL 272 >1EQ2-A nrPDB Length = 310 Score = 29.7 bits (65), Expect = 2.7, Method: Composition-based stats. Identities = 13/60 (21%), Positives = 21/60 (35%), Gaps = 4/60 (6%) Query: 335 LYYVREAHGIVVTDVAFLPEKGRGPELLGSHETALFSVAVDSRCQLHLLPSRRSVPVWLL 394 +Y RE H + VAF +L LF + + + + V +W L Sbjct: 170 VYGPREGHKGSMASVAFHLNT----QLNNGESPKLFEGSENFKRDFVYVGDVADVNLWFL 225 >1BJ4-A nrPDB Length = 470 Score = 29.3 bits (64), Expect = 2.9, Method: Composition-based stats. Identities = 20/86 (23%), Positives = 30/86 (34%), Gaps = 4/86 (4%) Query: 181 WKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQKDQLVTQLHWQENGPTF 240 +KV + V +A + +L K+VT G D + T E Sbjct: 314 FKVYQHQVVANCRALSEALTELGY----KIVTGGSDNHLILVDLRSKGTDGGRAEKVLEA 369 Query: 241 SSTPYRYQACRFGQVPDQPAGLRLFT 266 S C + +P+GLRL T Sbjct: 370 CSIACNKNTCPGDRSALRPSGLRLGT 395 >6N8P-A nrPDB Length = 979 Score = 29.3 bits (64), Expect = 3.0, Method: Composition-based stats. Identities = 14/53 (26%), Positives = 18/53 (33%) Query: 164 HDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRD 216 LL TG DG VR W + L +K + P+ G D Sbjct: 422 PQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVFLTDTDPNENFSAQGED 474 >5DKU-A nrPDB Length = 635 Score = 28.9 bits (63), Expect = 4.3, Method: Composition-based stats. Identities = 18/79 (22%), Positives = 32/79 (40%), Gaps = 11/79 (13%) Query: 126 KKCGAETQHEGLELRVENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRVWK--- 182 K CG Q GLE+ EN++ +Q + P+ FN + + DG +V + Sbjct: 77 KYCGLNIQTTGLEVFDENIRLIQIAVENYPVIIYDMFNINKKDIL----DGLRKVLENKN 132 Query: 183 ----VPSLEKVLEFKAHEG 197 + + + +F H Sbjct: 133 IIKIIQNGKFDAKFLLHNN 151 >5SUM-A nrPDB Length = 468 Score = 28.9 bits (63), Expect = 4.4, Method: Composition-based stats. Identities = 9/28 (32%), Positives = 17/28 (60%) Query: 164 HDNTLLATGGTDGYVRVWKVPSLEKVLE 191 HD L GG D YVR++ + + + +++ Sbjct: 375 HDGKYLLQGGLDRYVRIFDIKTNKMLVK 402 >2FTW-A nrPDB Length = 521 Score = 28.5 bits (62), Expect = 5.2, Method: Composition-based stats. Identities = 26/165 (15%), Positives = 47/165 (28%), Gaps = 25/165 (15%) Query: 191 EFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQKDQLVTQLHWQENGPTFSSTPYRYQAC 250 F A + + V D + VW+ +L W C Sbjct: 328 TFCADQKAMGKDDFTKIPNGVNGVEDRMSIVWENGVNTGKLTW----------------C 371 Query: 251 RFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSE 310 +F + R+F + R+ + WD + + + H V ++ E Sbjct: 372 QFVRATSSERA-RIFNIYPRKGRIDVGCDGDIVIWDPNQSKTISKDTHHHAVD--FNIFE 428 Query: 311 SGTFLGLGTVTGSVA--IYIAFSLQCLYYVREAHGIVVTDVAFLP 353 G+ T ++ L C+ + G V F P Sbjct: 429 GIKVTGIAVTTIVAGNIVWSDNKLSCV----KGSGRFVPRPPFGP 469 >5AMS-A nrPDB Length = 431 Score = 28.5 bits (62), Expect = 5.6, Method: Composition-based stats. Identities = 29/191 (15%), Positives = 59/191 (30%), Gaps = 29/191 (15%) Query: 163 NHDNTLLATGGTDGYVRVWKVPSL--EKVLEFKAHEGEIEDLALGPDGK-LVTVGRDLKA 219 + + L+ TGG D +W S + + + + +G LVT K Sbjct: 74 HPNLPLVCTGGGDNLAHLWTSHSQPPKFAGTLTGYGESVISCSFTSEGGFLVTADMSGKV 133 Query: 220 SV---------WQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIP 270 V W+ L +Q+ E + P R + + + Sbjct: 134 LVHMGQKGGAQWK---LASQMQEVEEIVWLKTHPT---IARTFAFGATDGSVWCYQINEQ 187 Query: 271 HKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAF 330 L Q ++ D S + T + + L ++ ++ + F Sbjct: 188 DGSLEQLMSGFVHQQDCSMGEFINTDKGENTLE-----------LVTCSLDSTIVAWNCF 236 Query: 331 SLQCLYYVREA 341 + Q L+ + +A Sbjct: 237 TGQQLFKITQA 247 >4MHC-A nrPDB Length = 826 Score = 27.8 bits (60), Expect = 9.2, Method: Composition-based stats. Identities = 33/209 (15%), Positives = 63/209 (30%), Gaps = 33/209 (15%) Query: 209 KLVTVGRDLKASVWQKDQLVTQLHWQENGPT-------FSSTPYRYQACRFGQVPDQPAG 261 + D K +W + ++ H + +P + V + Sbjct: 103 NYCWITSDNKLILWNINNS-SEYHCIDEIEHTILKVKLVKPSPNTF----VSSVENLLIV 157 Query: 262 LRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVT 321 LF + I G L+ G V + + +G G Sbjct: 158 ATLFDIYILTISFNDRTHELNIFNTG-----LKVNVTGFNVSNIISYERTGQIFFTGATD 212 Query: 322 G----------SVAIYIAFSLQ-CLYYVREAHGIVVTDVAFLPEKGRGPELLGS----HE 366 G S ++ + S + CL A+ + + +P ++L E Sbjct: 213 GVNVWELQYNCSENLFNSKSNKICLTKSNLANLLPTKLIPSIPGGKLIQKVLEGDAGTEE 272 Query: 367 TALFSVAVD-SRCQLHLLPSRRSVPVWLL 394 + + VD SR LH L ++ V +L+ Sbjct: 273 ETISQLEVDQSRGVLHTLSTKSIVRSYLI 301 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.317 0.130 0.365 Lambda K H 0.267 0.0398 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,905,974 Number of Sequences: 36641 Number of extensions: 612695 Number of successful extensions: 2793 Number of sequences better than 10.0: 147 Number of HSP's better than 10.0 without gapping: 180 Number of HSP's successfully gapped in prelim test: 65 Number of HSP's that attempted gapping in prelim test: 1544 Number of HSP's gapped (non-prelim): 846 length of query: 417 length of database: 10,336,785 effective HSP length: 100 effective length of query: 317 effective length of database: 6,672,685 effective search space: 2115241145 effective search space used: 2115241145 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 60 (27.8 bits)