BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9H867 (229 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4LG1-A nrPDB 458 e-129 4LEC-A nrPDB 109 1e-24 4QPN-A nrPDB 89 2e-18 4MTL-A nrPDB 67 7e-12 4M36-A nrPDB 44 6e-05 5EKU-A nrPDB 44 8e-05 3Q7E-A nrPDB 38 0.003 5DST-A nrPDB 34 0.054 2B3T-A nrPDB 33 0.15 3DMF-A nrPDB 32 0.21 6OGN-A nrPDB 31 0.48 3X0D-A nrPDB 31 0.57 3M70-A nrPDB 29 1.7 3K89-A nrPDB 28 2.3 3CCF-A nrPDB 28 2.6 5FUB-A nrPDB 28 3.2 5BNZ-A nrPDB 27 5.9 4ZLA-A nrPDB 27 6.3 4HGY-A nrPDB 27 6.7 >4LG1-A nrPDB Length = 224 Score = 458 bits (1178), Expect = e-129, Method: Compositional matrix adjust. Identities = 223/223 (100%), Positives = 223/223 (100%) Query: 7 SSLEDPLRSFVRVLEKRDGTVLRLQQYSSGGVGCVVWDAAIVLSKYLETPEFSGDGAHAL 66 SSLEDPLRSFVRVLEKRDGTVLRLQQYSSGGVGCVVWDAAIVLSKYLETPEFSGDGAHAL Sbjct: 2 SSLEDPLRSFVRVLEKRDGTVLRLQQYSSGGVGCVVWDAAIVLSKYLETPEFSGDGAHAL 61 Query: 67 SRRSVLELGSGTGAVGLMAATLGADVVVTDLEELQDLLKMNINMNKHLVTGSVQAKVLKW 126 SRRSVLELGSGTGAVGLMAATLGADVVVTDLEELQDLLKMNINMNKHLVTGSVQAKVLKW Sbjct: 62 SRRSVLELGSGTGAVGLMAATLGADVVVTDLEELQDLLKMNINMNKHLVTGSVQAKVLKW 121 Query: 127 GEEIEGFPSPPDFILMADCIYYEESLEPLLKTLKDISGFETCIICCYEQRTMGKNPEIEK 186 GEEIEGFPSPPDFILMADCIYYEESLEPLLKTLKDISGFETCIICCYEQRTMGKNPEIEK Sbjct: 122 GEEIEGFPSPPDFILMADCIYYEESLEPLLKTLKDISGFETCIICCYEQRTMGKNPEIEK 181 Query: 187 KYFELLQLDFDFEKIPLEKHDEEYRSEDIHIIYIRKKKSKFPS 229 KYFELLQLDFDFEKIPLEKHDEEYRSEDIHIIYIRKKKSKFPS Sbjct: 182 KYFELLQLDFDFEKIPLEKHDEEYRSEDIHIIYIRKKKSKFPS 224 >4LEC-A nrPDB Length = 212 Score = 109 bits (273), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 76/199 (38%), Positives = 106/199 (53%), Gaps = 21/199 (10%) Query: 31 QQYSSGGVGCVVWDAAIVLSKYLETPEFSGDGAHALSRRSVLELGSGTGAVGLMAATLGA 90 Q + GV VVWDAAIVLS YLE GA L RS +ELG+GTG VG++AA LGA Sbjct: 29 QDWRHLGVAAVVWDAAIVLSTYLEM------GAVELRGRSAVELGAGTGLVGIVAALLGA 82 Query: 91 DVVVTDLEELQDLLKMNI--NMNKHLVTGSVQAKVLKWGEEIEGF-PSPPDFILMADCIY 147 V +TD + + LK N+ N+ H+ T +V K L WG+ + F P D IL AD IY Sbjct: 83 HVTITDRKVALEFLKSNVQANLPPHIQTKTV-VKELTWGQNLGSFSPGEFDLILGADIIY 141 Query: 148 YEESLEPLLKTLKDISGFETCIICCYEQRTMGKNPEIEKKYFELLQLDFDFEKIPLEKHD 207 EE+ LL+TL+ + + I+ R E + + +L+ F K+ +D Sbjct: 142 LEETFTDLLQTLEHLCSNHSVILLACRIRY-----ERDNNFLAMLERQFTVRKV---HYD 193 Query: 208 EEYRSEDIHIIYIRKKKSK 226 E +D+HI +K+ K Sbjct: 194 PE---KDVHIYEAQKRNQK 209 >4QPN-A nrPDB Length = 227 Score = 88.6 bits (218), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 67/204 (32%), Positives = 97/204 (47%), Gaps = 18/204 (8%) Query: 25 GTVLRLQQY--SSGGVGCVVWDAAIVLSKYLETPEFSGDGAHALSRRSVLELGSGTGAVG 82 G VL + Q S GV VWDAA+ L Y E+ G + V+ELG+GTG VG Sbjct: 38 GHVLTITQNFGSRLGVAARVWDAALSLCNYFESQNVDFRG------KKVIELGAGTGIVG 91 Query: 83 LMAATLGADVVVTDLEELQDLLKMNINMNKHLVTGSVQAKVLKWGEEIEGFPSPPDFILM 142 ++AA G DV +TDL + ++ N+ N G Q + L WG + FP+ D +L Sbjct: 92 ILAALQGGDVTITDLPLALEQIQGNVQANV-PAGGQAQVRALSWGIDHHVFPANYDLVLG 150 Query: 143 ADCIYYEESLEPLLKTLKDISGFETCIICCYEQRTMGKNPEIEKKYFELLQLDFDFEKIP 202 AD +Y E + LL TL+ + I Y M K E + LL F E Sbjct: 151 ADIVYLEPTFPLLLGTLQHLCRPHGTI---YLASKMRKEHGTESFFQHLLPQHFQLE--- 204 Query: 203 LEKHDEEYRSEDIHIIYIRKKKSK 226 L + DE+ E+++I R ++ + Sbjct: 205 LAQRDED---ENVNIYRARHREPR 225 >4MTL-A nrPDB Length = 244 Score = 67.0 bits (162), Expect = 7e-12, Method: Compositional matrix adjust. Identities = 47/145 (32%), Positives = 78/145 (53%), Gaps = 13/145 (8%) Query: 39 GCVVWDAAIVLSKYLETPEFSGDGAHALSRR--SVLELGSGTGAVGLMAATLGADVVVTD 96 G VVW A+ L +YLE + A L+ + +LE+G+G G V ++A+ LGA V TD Sbjct: 68 GAVVWPGAMALCQYLE------EHAEELNFQDAKILEIGAGPGLVSIVASILGAQVTATD 121 Query: 97 LEELQDLLKMNINMNKHLVTGSV-QAKVLKWGEEIE-GFPSPP---DFILMADCIYYEES 151 L ++ L+ N+ N T + + K L WGE+++ FP D++L +D +Y+ Sbjct: 122 LPDVLGNLQYNLLKNTLQCTAHLPEVKELVWGEDLDKNFPKSAFYYDYVLASDVVYHHYF 181 Query: 152 LEPLLKTLKDISGFETCIICCYEQR 176 L+ LL T+ +S T ++ + R Sbjct: 182 LDKLLTTMVYLSQPGTVLLWANKFR 206 >4M36-A nrPDB Length = 343 Score = 43.9 bits (102), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 31/88 (35%), Positives = 43/88 (48%), Gaps = 19/88 (21%) Query: 64 HALSRRSVLELGSGTGAVGLMAATLGAD--VVVTDLEELQDLLKMNINMNK--------H 113 H VLE+G+G+G + LMAA LGA V V EEL L + NI N H Sbjct: 57 HVTPETGVLEIGAGSGLLSLMAAKLGAKWVVAVEGSEELAKLARENIRANNMEHQVKVLH 116 Query: 114 LVTGSVQAKVLKWGEEIEGFPSPPDFIL 141 +++ +++K L P PPD +L Sbjct: 117 MMSTELKSKHL---------PEPPDVLL 135 >5EKU-A nrPDB Length = 390 Score = 43.5 bits (101), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 31/88 (35%), Positives = 42/88 (47%), Gaps = 19/88 (21%) Query: 64 HALSRRSVLELGSGTGAVGLMAATLGAD--VVVTDLEELQDLLKMNINMNK--------H 113 H VLE+G+G+G + LMAA LGA V V EEL L + NI N H Sbjct: 92 HVTPETGVLEIGAGSGLLSLMAAKLGAKWVVAVEGSEELAKLARENIRANNMEHQVKVLH 151 Query: 114 LVTGSVQAKVLKWGEEIEGFPSPPDFIL 141 +++ ++ K L P PPD +L Sbjct: 152 MMSTELKPKHL---------PEPPDVLL 170 >3Q7E-A nrPDB Length = 349 Score = 38.1 bits (87), Expect = 0.003, Method: Compositional matrix adjust. Identities = 32/99 (32%), Positives = 49/99 (49%), Gaps = 11/99 (11%) Query: 64 HALSRRSVLELGSGTGAVGLMAATLGADVVV-TDLEELQDLLKMNINMNK--HLVTGSVQ 120 H + VL++GSGTG + + AA GA V+ + + D + NK H+VT ++ Sbjct: 63 HLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVT-IIK 121 Query: 121 AKVLKWGEEIEGFPSPPDFIL---MADCIYYEESLEPLL 156 KV EE+E D I+ M C++YE L +L Sbjct: 122 GKV----EEVELPVEKVDIIISEWMGYCLFYESMLNTVL 156 >5DST-A nrPDB Length = 332 Score = 33.9 bits (76), Expect = 0.054, Method: Compositional matrix adjust. Identities = 30/99 (30%), Positives = 46/99 (46%), Gaps = 11/99 (11%) Query: 64 HALSRRSVLELGSGTGAVGLMAATLGADVVV-TDLEELQDLLKMNINMNKHL--VTGSVQ 120 H + VL++GSGTG + + AA GA V + + D + I N HL + + Sbjct: 46 HVFKDKVVLDVGSGTGILSMFAAKAGAKKVFGIECSSISDYSEKIIKAN-HLDNIITIFK 104 Query: 121 AKVLKWGEEIEGFPSPPDFIL---MADCIYYEESLEPLL 156 KV EE+E D I+ M C++YE L ++ Sbjct: 105 GKV----EEVELPVEKVDIIISEWMGYCLFYESMLNTVI 139 >2B3T-A nrPDB Length = 276 Score = 32.7 bits (73), Expect = 0.15, Method: Compositional matrix adjust. Identities = 18/75 (24%), Positives = 35/75 (46%), Gaps = 5/75 (6%) Query: 71 VLELGSGTGAVGLMAATLGADVVVTDLEELQDLLKMNINMNKHLVTGSVQAKVLKW---- 126 +L+LG+GTGA+ L A+ D + ++ + D + + +HL ++ W Sbjct: 113 ILDLGTGTGAIALALASERPDCEIIAVDRMPDAVSLAQRNAQHLAIKNIHILQSDWFSAL 172 Query: 127 -GEEIEGFPSPPDFI 140 G++ S P +I Sbjct: 173 AGQQFAMIVSNPPYI 187 >3DMF-A nrPDB Length = 381 Score = 32.0 bits (71), Expect = 0.21, Method: Compositional matrix adjust. Identities = 21/63 (33%), Positives = 36/63 (57%), Gaps = 5/63 (7%) Query: 62 GAHALSRRSVLELGSGTGAVGLMAATLGADVVVTDLEELQDLLKMNINMNKHLVTGSVQA 121 G + R VL+LG+G GA+ L A +GA+VV ++D L +++ K L +++A Sbjct: 228 GPEGVRGRQVLDLGAGYGALTLPLARMGAEVV-----GVEDDLASVLSLQKGLEANALKA 282 Query: 122 KVL 124 + L Sbjct: 283 QAL 285 >6OGN-A nrPDB Length = 692 Score = 30.8 bits (68), Expect = 0.48, Method: Compositional matrix adjust. Identities = 12/21 (57%), Positives = 17/21 (80%) Query: 71 VLELGSGTGAVGLMAATLGAD 91 VL++G+GTG + +MA T GAD Sbjct: 68 VLDIGTGTGLLSMMAVTAGAD 88 >3X0D-A nrPDB Length = 655 Score = 30.8 bits (68), Expect = 0.57, Method: Compositional matrix adjust. Identities = 14/25 (56%), Positives = 18/25 (72%) Query: 71 VLELGSGTGAVGLMAATLGADVVVT 95 VL++G+GTG + LMAA GAD V Sbjct: 76 VLDIGTGTGLLSLMAAREGADKVTA 100 >3M70-A nrPDB Length = 286 Score = 28.9 bits (63), Expect = 1.7, Method: Compositional matrix adjust. Identities = 20/54 (37%), Positives = 23/54 (42%), Gaps = 3/54 (5%) Query: 49 LSKYLETPEFSGD---GAHALSRRSVLELGSGTGAVGLMAATLGADVVVTDLEE 99 SK T GD A +S VL+LG G G L + LG DV D E Sbjct: 99 FSKKYNTTAIHGDVVDAAKIISPCKVLDLGCGQGRNSLYLSLLGYDVTSWDHNE 152 >3K89-A nrPDB Length = 314 Score = 28.5 bits (62), Expect = 2.3, Method: Compositional matrix adjust. Identities = 23/68 (33%), Positives = 30/68 (44%), Gaps = 5/68 (7%) Query: 61 DGAHALSRRSVLELGSGTGAVGLMAATLGA-DVVVTDL----EELQDLLKMNINMNKHLV 115 DGAH + R + VG MAA LGA D VV ++ Q ++ N N +V Sbjct: 111 DGAHLVRLRGQFMQAAAPAGVGAMAAVLGAEDAVVLEVCAEAAGSQVVVPANFNSPGQIV 170 Query: 116 TGSVQAKV 123 G A V Sbjct: 171 IGGDAAAV 178 >3CCF-A nrPDB Length = 279 Score = 28.5 bits (62), Expect = 2.6, Method: Compositional matrix adjust. Identities = 21/72 (29%), Positives = 34/72 (47%), Gaps = 3/72 (4%) Query: 28 LRLQQYSSGGVGCVVWDAAIVLSKYLETPEFSGDGAHALSRRS---VLELGSGTGAVGLM 84 L Q ++ G WDA + K+ ++ D L+ + +L+LG GTG + Sbjct: 15 LYFQGMTNLGTAKNFWDATLYQDKHSFVWQYGEDLLQLLNPQPGEFILDLGCGTGQLTEK 74 Query: 85 AATLGADVVVTD 96 A GA+V+ TD Sbjct: 75 IAQSGAEVLGTD 86 >5FUB-A nrPDB Length = 337 Score = 28.1 bits (61), Expect = 3.2, Method: Compositional matrix adjust. Identities = 28/103 (27%), Positives = 43/103 (41%), Gaps = 21/103 (20%) Query: 65 ALSRRSVLELGSGTGAVGLMAATLGADVVVTDL------EELQDLLKMNINMNKHLVTGS 118 AL + VL+LG GTG + L A L V + E ++L+K N Sbjct: 42 ALREKVVLDLGCGTGVISLFCALLAKPAGVYAVEASSMAEHTEELVKQN----------G 91 Query: 119 VQAKVLKWGEEIEG--FPSPPDFIL---MADCIYYEESLEPLL 156 V + E E P+ D ++ M +C+ +E LE +L Sbjct: 92 CDGVVTVFQERAENLTLPTKVDVLVSEWMGNCLLFEYMLESVL 134 >5BNZ-A nrPDB Length = 564 Score = 27.3 bits (59), Expect = 5.9, Method: Compositional matrix adjust. Identities = 12/30 (40%), Positives = 17/30 (56%) Query: 157 KTLKDISGFETCIICCYEQRTMGKNPEIEK 186 + +KD G + C Y+ T+GKNPE K Sbjct: 431 EAIKDADGNIVELRCSYDPDTLGKNPEGRK 460 >4ZLA-A nrPDB Length = 502 Score = 27.3 bits (59), Expect = 6.3, Method: Compositional matrix adjust. Identities = 19/72 (26%), Positives = 35/72 (48%), Gaps = 8/72 (11%) Query: 140 ILMADCIYYEESLEP-LLKTLKDISGFETCIICC--YEQRTMGKNPEIEKKYFELLQLDF 196 +++ADC+ Y + L P ++ ++G C++ + MG N E+ K FE L+ Sbjct: 351 LVLADCLSYAQDLNPDVIVDFATLTG--ACVVGLGEFTSAIMGHNEEL-KNLFETSGLES 407 Query: 197 D--FEKIPLEKH 206 K+P +H Sbjct: 408 GELLAKLPFNRH 419 >4HGY-A nrPDB Length = 276 Score = 26.9 bits (58), Expect = 6.7, Method: Compositional matrix adjust. Identities = 14/24 (58%), Positives = 15/24 (62%) Query: 69 RSVLELGSGTGAVGLMAATLGADV 92 R VLELG GTG V A LG +V Sbjct: 64 RPVLELGVGTGRVAFPLADLGVEV 87 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4LG1-A nrPDB 351 1e-97 4QPN-A nrPDB 257 4e-69 4LEC-A nrPDB 233 5e-62 4MTL-A nrPDB 172 1e-43 4M36-A nrPDB 79 1e-15 5EKU-A nrPDB 78 3e-15 Sequences not found previously or not previously below threshold: 4PWY-A nrPDB 44 4e-05 3MGG-A nrPDB 43 1e-04 3CJR-A nrPDB 39 0.002 1F3L-A nrPDB 39 0.002 4RYL-A nrPDB 38 0.004 1JG3-A nrPDB 36 0.010 5LV5-A nrPDB 36 0.012 5EGS-A nrPDB 36 0.015 6CU3-A nrPDB 36 0.017 3DMF-A nrPDB 35 0.025 4INE-A nrPDB 35 0.032 1G6Q-1 nrPDB 35 0.036 3X0D-A nrPDB 34 0.061 5DST-A nrPDB 33 0.083 1WY7-A nrPDB 33 0.089 5FUB-A nrPDB 33 0.094 1WS6-A nrPDB 33 0.12 3Q7E-A nrPDB 33 0.13 4HGY-A nrPDB 32 0.15 5BP9-A nrPDB 32 0.16 3M70-A nrPDB 32 0.22 3CCF-A nrPDB 32 0.27 4LWO-B nrPDB 32 0.27 4KRI-A nrPDB 32 0.29 6OGN-A nrPDB 31 0.43 3EGE-A nrPDB 31 0.46 2I6G-A nrPDB 31 0.54 5WP4-A nrPDB 30 0.70 3E05-A nrPDB 30 1.0 4L7V-A nrPDB 30 1.1 6GXV-A nrPDB 30 1.1 1DUS-A nrPDB 29 1.3 4NIF-A nrPDB 29 1.6 4AJU-A nrPDB 29 1.7 4R0V-A nrPDB 29 2.0 2B3T-A nrPDB 29 2.2 6IFX-A nrPDB 29 2.2 6IFV-A nrPDB 29 2.3 3K89-A nrPDB 29 2.6 5AH0-A nrPDB 28 2.7 2YXE-A nrPDB 28 3.1 5YYS-A nrPDB 28 3.1 2YVL-A nrPDB 28 3.7 3GRP-A nrPDB 27 5.3 3HZZ-A nrPDB 27 6.5 1L2L-A nrPDB 27 9.6 >4LG1-A nrPDB Length = 224 Score = 351 bits (901), Expect = 1e-97, Method: Composition-based stats. Identities = 223/223 (100%), Positives = 223/223 (100%) Query: 7 SSLEDPLRSFVRVLEKRDGTVLRLQQYSSGGVGCVVWDAAIVLSKYLETPEFSGDGAHAL 66 SSLEDPLRSFVRVLEKRDGTVLRLQQYSSGGVGCVVWDAAIVLSKYLETPEFSGDGAHAL Sbjct: 2 SSLEDPLRSFVRVLEKRDGTVLRLQQYSSGGVGCVVWDAAIVLSKYLETPEFSGDGAHAL 61 Query: 67 SRRSVLELGSGTGAVGLMAATLGADVVVTDLEELQDLLKMNINMNKHLVTGSVQAKVLKW 126 SRRSVLELGSGTGAVGLMAATLGADVVVTDLEELQDLLKMNINMNKHLVTGSVQAKVLKW Sbjct: 62 SRRSVLELGSGTGAVGLMAATLGADVVVTDLEELQDLLKMNINMNKHLVTGSVQAKVLKW 121 Query: 127 GEEIEGFPSPPDFILMADCIYYEESLEPLLKTLKDISGFETCIICCYEQRTMGKNPEIEK 186 GEEIEGFPSPPDFILMADCIYYEESLEPLLKTLKDISGFETCIICCYEQRTMGKNPEIEK Sbjct: 122 GEEIEGFPSPPDFILMADCIYYEESLEPLLKTLKDISGFETCIICCYEQRTMGKNPEIEK 181 Query: 187 KYFELLQLDFDFEKIPLEKHDEEYRSEDIHIIYIRKKKSKFPS 229 KYFELLQLDFDFEKIPLEKHDEEYRSEDIHIIYIRKKKSKFPS Sbjct: 182 KYFELLQLDFDFEKIPLEKHDEEYRSEDIHIIYIRKKKSKFPS 224 >4QPN-A nrPDB Length = 227 Score = 257 bits (655), Expect = 4e-69, Method: Composition-based stats. Identities = 67/204 (32%), Positives = 97/204 (47%), Gaps = 18/204 (8%) Query: 25 GTVLRLQQY--SSGGVGCVVWDAAIVLSKYLETPEFSGDGAHALSRRSVLELGSGTGAVG 82 G VL + Q S GV VWDAA+ L Y E+ G + V+ELG+GTG VG Sbjct: 38 GHVLTITQNFGSRLGVAARVWDAALSLCNYFESQNVDFRG------KKVIELGAGTGIVG 91 Query: 83 LMAATLGADVVVTDLEELQDLLKMNINMNKHLVTGSVQAKVLKWGEEIEGFPSPPDFILM 142 ++AA G DV +TDL + ++ N+ N G Q + L WG + FP+ D +L Sbjct: 92 ILAALQGGDVTITDLPLALEQIQGNVQANV-PAGGQAQVRALSWGIDHHVFPANYDLVLG 150 Query: 143 ADCIYYEESLEPLLKTLKDISGFETCIICCYEQRTMGKNPEIEKKYFELLQLDFDFEKIP 202 AD +Y E + LL TL+ + I Y M K E + LL F E Sbjct: 151 ADIVYLEPTFPLLLGTLQHLCRPHGTI---YLASKMRKEHGTESFFQHLLPQHFQLE--- 204 Query: 203 LEKHDEEYRSEDIHIIYIRKKKSK 226 L + DE+ E+++I R ++ + Sbjct: 205 LAQRDED---ENVNIYRARHREPR 225 >4LEC-A nrPDB Length = 212 Score = 233 bits (594), Expect = 5e-62, Method: Composition-based stats. Identities = 76/199 (38%), Positives = 105/199 (52%), Gaps = 21/199 (10%) Query: 31 QQYSSGGVGCVVWDAAIVLSKYLETPEFSGDGAHALSRRSVLELGSGTGAVGLMAATLGA 90 Q + GV VVWDAAIVLS YLE GA L RS +ELG+GTG VG++AA LGA Sbjct: 29 QDWRHLGVAAVVWDAAIVLSTYLEM------GAVELRGRSAVELGAGTGLVGIVAALLGA 82 Query: 91 DVVVTDLEELQDLLKMNINMN--KHLVTGSVQAKVLKWGEEIEGF-PSPPDFILMADCIY 147 V +TD + + LK N+ N H+ T +V K L WG+ + F P D IL AD IY Sbjct: 83 HVTITDRKVALEFLKSNVQANLPPHIQTKTV-VKELTWGQNLGSFSPGEFDLILGADIIY 141 Query: 148 YEESLEPLLKTLKDISGFETCIICCYEQRTMGKNPEIEKKYFELLQLDFDFEKIPLEKHD 207 EE+ LL+TL+ + + I+ R E + + +L+ F K+ +D Sbjct: 142 LEETFTDLLQTLEHLCSNHSVILLACRIRY-----ERDNNFLAMLERQFTVRKV---HYD 193 Query: 208 EEYRSEDIHIIYIRKKKSK 226 E +D+HI +K+ K Sbjct: 194 PE---KDVHIYEAQKRNQK 209 >4MTL-A nrPDB Length = 244 Score = 172 bits (436), Expect = 1e-43, Method: Composition-based stats. Identities = 49/166 (29%), Positives = 85/166 (51%), Gaps = 18/166 (10%) Query: 39 GCVVWDAAIVLSKYLETPEFSGDGAHALSRR--SVLELGSGTGAVGLMAATLGADVVVTD 96 G VVW A+ L +YLE + A L+ + +LE+G+G G V ++A+ LGA V TD Sbjct: 68 GAVVWPGAMALCQYLE------EHAEELNFQDAKILEIGAGPGLVSIVASILGAQVTATD 121 Query: 97 LEELQDLLKMNINMNKHLVTGSV-QAKVLKWGEEIE-GFPSP---PDFILMADCIYYEES 151 L ++ L+ N+ N T + + K L WGE+++ FP D++L +D +Y+ Sbjct: 122 LPDVLGNLQYNLLKNTLQCTAHLPEVKELVWGEDLDKNFPKSAFYYDYVLASDVVYHHYF 181 Query: 152 LEPLLKTLKDISGFETCIICCYEQRTMGKNPEIEKKYFELLQLDFD 197 L+ LL T+ +S T ++ + R + ++ + + FD Sbjct: 182 LDKLLTTMVYLSQPGTVLLWANKFRF-----STDYEFLDKFKQVFD 222 >4M36-A nrPDB Length = 343 Score = 79.4 bits (194), Expect = 1e-15, Method: Composition-based stats. Identities = 39/168 (23%), Positives = 64/168 (38%), Gaps = 34/168 (20%) Query: 64 HALSRRSVLELGSGTGAVGLMAATLGAD--VVVTDLEELQDLLKMNINMNK--------H 113 H VLE+G+G+G + LMAA LGA V V EEL L + NI N H Sbjct: 57 HVTPETGVLEIGAGSGLLSLMAAKLGAKWVVAVEGSEELAKLARENIRANNMEHQVKVLH 116 Query: 114 LVTGSVQAKVLKWGEEIEGFPSPPDFILM---ADCIYYEESLEPLLKTLKDISGFETCII 170 +++ +++K L P PPD +L + E +L+ ++ + T II Sbjct: 117 MMSTELKSKHL---------PEPPDVLLSEIFGTMMLGESALDYVVDVRNRLLKPTTKII 167 Query: 171 ------------CCYEQRTMGKNPEIEKKYFELLQLDFDFEKIPLEKH 206 C R + + ++ L + + + Sbjct: 168 PQFGTQYAVPIECDALHRISSVSGWRDLDLKHMMTLQDTVSIVFAKHY 215 >5EKU-A nrPDB Length = 390 Score = 77.9 bits (190), Expect = 3e-15, Method: Composition-based stats. Identities = 39/168 (23%), Positives = 63/168 (37%), Gaps = 34/168 (20%) Query: 64 HALSRRSVLELGSGTGAVGLMAATLGAD--VVVTDLEELQDLLKMNINMNK--------H 113 H VLE+G+G+G + LMAA LGA V V EEL L + NI N H Sbjct: 92 HVTPETGVLEIGAGSGLLSLMAAKLGAKWVVAVEGSEELAKLARENIRANNMEHQVKVLH 151 Query: 114 LVTGSVQAKVLKWGEEIEGFPSPPDFILM---ADCIYYEESLEPLLKTLKDISGFETCII 170 +++ ++ K L P PPD +L + E +L+ ++ + T II Sbjct: 152 MMSTELKPKHL---------PEPPDVLLSEIFGTMMLGESALDYVVDVRNRLLKPTTKII 202 Query: 171 ------------CCYEQRTMGKNPEIEKKYFELLQLDFDFEKIPLEKH 206 C R + + ++ L + + + Sbjct: 203 PQFGTQYAVPIECDALHRISSVSGWRDLDLKHMMTLQDTVSIVFAKHY 250 >4PWY-A nrPDB Length = 264 Score = 44.4 bits (103), Expect = 4e-05, Method: Composition-based stats. Identities = 38/196 (19%), Positives = 71/196 (36%), Gaps = 31/196 (15%) Query: 42 VWDAAIVLSKYLETPEFSGDGAHALSRRSVLELGSG-TGAVGLMAATLG--ADVVVTD-L 97 +W + VL+ Y + +V ELG G T GLM A +V++TD Sbjct: 68 IWPSEEVLAYY------CLKHNNIFRALAVCELGGGMTCLAGLMVAISADVKEVLLTDGN 121 Query: 98 EELQDLLKMNINMNKH---LVTGSVQAKVLKWGEEIEG--FPSPPDFILMADCIYYEESL 152 E+ ++ I N+ T + + L+W E + D ++ ADC++ ++ Sbjct: 122 EKAIRNVQDIITRNQKAGVFKTQKISSCFLRWDNETDVSQLEGHFDIVMCADCLFLDQYR 181 Query: 153 EPLLKTLKDISGFETCII------------CCYEQRTMGKNPEIEKKYFELLQLDFDFEK 200 L+ +K + + C G + + Y E Sbjct: 182 ASLVDAIKRLLQPRGKAMVFAPRRGNTLNQFCNLAEKAGFCIQRHENYDE----HISNFH 237 Query: 201 IPLEKHDEEYRSEDIH 216 L+K + + E++H Sbjct: 238 SKLKKENPDIYEENLH 253 >3MGG-A nrPDB Length = 276 Score = 42.8 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 32/128 (25%), Positives = 47/128 (36%), Gaps = 8/128 (6%) Query: 46 AIVLSKYLETPEFSGDGAHALS-RRSVLELGSGTGAVGLMAATLGADVVVTD---LEELQ 101 A+ LS+ ET E VLE G G GA ++ A D +T E Sbjct: 15 ALRLSEQAETLEKLLHHDTVYPPGAKVLEAGCGIGAQTVILAKNNPDAEITSIDISPESL 74 Query: 102 DLLKMNINMNKHLVTGSVQAKVLKWGEEIEGFPSPPDFILMADCIYYEESLEPLLKTLKD 161 + + N N +QA + E F D I + + + +S E LK+LK Sbjct: 75 EKARENTEKNGIKNVKFLQANIFSLPFEDSSF----DHIFVCFVLEHLQSPEEALKSLKK 130 Query: 162 ISGFETCI 169 + I Sbjct: 131 VLKPGGTI 138 >3CJR-A nrPDB Length = 254 Score = 38.6 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 20/92 (21%), Positives = 35/92 (38%), Gaps = 7/92 (7%) Query: 64 HALSRRSVLELGSGTGAVGLMAATLGADVVVTDL-EELQDLLKMNINMNKHLVTGSVQAK 122 H VL+LG+G+G + + A LG + D+ + + N N V+ + Sbjct: 117 HLRPGDKVLDLGTGSGVLAIAAEKLGGKALGVDIDPMVLPQAEANAKRN------GVRPR 170 Query: 123 VLKWGEEIEGFPSPPDFILMADCIYYEESLEP 154 L+ E P D ++ +L P Sbjct: 171 FLEGSLEAALPFGPFDLLVANLYAELHAALAP 202 >1F3L-A nrPDB Length = 321 Score = 38.6 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 19/61 (31%), Positives = 28/61 (45%), Gaps = 1/61 (1%) Query: 57 EFSGDGAHALSRRSVLELGSGTGAVGLMAATLGA-DVVVTDLEELQDLLKMNINMNKHLV 115 +F H + VL++G GTG + + AA GA V+ D E+ I +NK Sbjct: 35 DFIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAKKVIAVDQSEILYQAMDIIRLNKLED 94 Query: 116 T 116 T Sbjct: 95 T 95 >4RYL-A nrPDB Length = 340 Score = 37.8 bits (86), Expect = 0.004, Method: Composition-based stats. Identities = 26/100 (26%), Positives = 40/100 (40%), Gaps = 6/100 (6%) Query: 21 EKRDGTVLRLQQYSSGGVGCVVWDAAIVLSKYLETPEFSGDGAHALSRRSVLELGSGTGA 80 E DG + Y G+ + I Y +F H + VL++G GTG Sbjct: 23 EDEDG--VYFSSYGHYGIHEEMLKDKIRTESY---RDFIYQNPHIFKDKVVLDVGCGTGI 77 Query: 81 VGLMAATLGA-DVVVTDLEELQDLLKMNINMNKHLVTGSV 119 + + AA GA V+ D E+ I +NK T ++ Sbjct: 78 LSMFAAKAGAKKVLGVDQSEILYQAMDIIRLNKLEDTITL 117 >1JG3-A nrPDB Length = 235 Score = 36.3 bits (82), Expect = 0.010, Method: Composition-based stats. Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 10/83 (12%) Query: 63 AHALSRRSVLELGSGTGA-VGLMAATLGADV-VVTDLEELQDLLKMNINMNKHLVTGSVQ 120 A+ ++LE+G+G+G L++ + DV + + EL + K N+ V+ Sbjct: 87 ANLKPGMNILEVGTGSGWNAALISEIVKTDVYTIERIPELVEFAKRNLER------AGVK 140 Query: 121 AKVLKWGEEIEGFP--SPPDFIL 141 + G+ +GFP +P D I+ Sbjct: 141 NVHVILGDGSKGFPPKAPYDVII 163 >5LV5-A nrPDB Length = 403 Score = 36.3 bits (82), Expect = 0.012, Method: Composition-based stats. Identities = 23/112 (20%), Positives = 41/112 (36%), Gaps = 8/112 (7%) Query: 65 ALSRRSVLELGSGTGAVGLMAATLGA-DVVVTDLEELQDLLKMNINMNKHLVTGSVQAKV 123 AL ++VL++G+GTG + + A GA V + + + + +N + V Sbjct: 108 ALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRLN----GLEDRVHV 163 Query: 124 LKWGEEIEGFPSPPDFILMADCIY---YEESLEPLLKTLKDISGFETCIICC 172 L E P D I+ Y +E L +L ++ Sbjct: 164 LPGPVETVELPERVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPA 215 >5EGS-A nrPDB Length = 376 Score = 35.9 bits (81), Expect = 0.015, Method: Composition-based stats. Identities = 23/112 (20%), Positives = 40/112 (35%), Gaps = 8/112 (7%) Query: 65 ALSRRSVLELGSGTGAVGLMAATLGA-DVVVTDLEELQDLLKMNINMNKHLVTGSVQAKV 123 AL ++VL++G+GTG + + A GA V + + + + N + V Sbjct: 81 ALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASAIWQQAREVVRFN----GLEDRVHV 136 Query: 124 LKWGEEIEGFPSPPDFILMADCIY---YEESLEPLLKTLKDISGFETCIICC 172 L E P D I+ Y +E L +L ++ Sbjct: 137 LPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHARTKWLKEGGLLLPA 188 >6CU3-A nrPDB Length = 336 Score = 35.5 bits (80), Expect = 0.017, Method: Composition-based stats. Identities = 29/124 (23%), Positives = 45/124 (36%), Gaps = 14/124 (11%) Query: 56 PEFSGDGAHALSRRSVLELGSGTGAVGLMAATLGAD-VVVTDLEELQDLLKMNINMNKHL 114 H + VL++G GTG + L AA GA V+ D+ ++ D + ++ N Sbjct: 40 KNAILQNKHLFKDKVVLDIGCGTGILCLFAAKAGAKRVIGIDMSDIIDKARQIVSDN--- 96 Query: 115 VTGSVQAKVLKWG--EEIEGFP---SPPDFILMADCIY---YEESLEPLLKTLKDISGFE 166 G L G E+I P D I+ Y YE L+ +L Sbjct: 97 --GYSHVIELIKGKVEDIAQLPFGIEKVDIIISEWMGYFLLYESMLQTVLSARDRWLRPG 154 Query: 167 TCII 170 + Sbjct: 155 GYLF 158 >3DMF-A nrPDB Length = 381 Score = 35.1 bits (79), Expect = 0.025, Method: Composition-based stats. Identities = 29/108 (26%), Positives = 42/108 (38%), Gaps = 6/108 (5%) Query: 12 PLRSFVRVLEKRD-GTVLRLQQYSSGGVGCVVWDAAIVLSKYLETPEFSGDGAHALSRRS 70 PL S R R G V A+++L + L+ G + R Sbjct: 181 PLPSLWRAFSARILGAEYTFHHLPGVFSAGKVDPASLLLLEALQERL----GPEGVRGRQ 236 Query: 71 VLELGSGTGAVGLMAATLGADVV-VTDLEELQDLLKMNINMNKHLVTG 117 VL+LG+G GA+ L A +GA+VV V D L+ + N Sbjct: 237 VLDLGAGYGALTLPLARMGAEVVGVEDDLASVLSLQKGLEANALKAQA 284 >4INE-A nrPDB Length = 454 Score = 34.8 bits (78), Expect = 0.032, Method: Composition-based stats. Identities = 38/206 (18%), Positives = 68/206 (33%), Gaps = 22/206 (10%) Query: 3 DTLESS--LEDPLRSFVRVLEKR------DGTV-----LRLQQYSSGGVGCVVWDAAIVL 49 D +E S +E F+ V K+ D T+ L QY++ G+ W + Sbjct: 161 DQVEHSNYVEQNFLDFIFVFRKKVFAPTTDATITFRDFLDKTQYTNTGIDAYEWMFGVNF 220 Query: 50 SK---YLETPEFSGDGAHALSRRSVLELGSG-TGAVGLMAATLGADVVVTDLE-ELQDLL 104 Y E + +++L++G G G +A G V DL + + Sbjct: 221 ISPGGYDENLKIIKRFGDFKPGQTMLDIGVGIGGGARQVADEFGVHVHGIDLSSNMLAIA 280 Query: 105 KMNINMNKHLVTGSVQAKVLKWGEEIEGFPSPPDFILMADCIYYEESLEPLLKTLKDISG 164 ++ K L + E F D++ DCI + E L + Sbjct: 281 LERLHEEKDSRVKYSITDALVYQFEDNSF----DYVFSRDCIQHIPDTEKLFSRIYKALK 336 Query: 165 FETCIICCYEQRTMGKNPEIEKKYFE 190 ++ + G+ + K Y Sbjct: 337 PGGKVLITMYGKGYGEQSDKFKTYVA 362 >1G6Q-1 nrPDB Length = 328 Score = 34.8 bits (78), Expect = 0.036, Method: Composition-based stats. Identities = 15/60 (25%), Positives = 27/60 (45%), Gaps = 1/60 (1%) Query: 53 LETPEFSGDGAHALSRRSVLELGSGTGAVGLMAATLGA-DVVVTDLEELQDLLKMNINMN 111 L + VL++G GTG + + AA GA V+ D+ + ++ K + +N Sbjct: 24 LSYRNAIIQNKDLFKDKIVLDVGCGTGILSMFAAKHGAKHVIGVDMSSIIEMAKELVELN 83 >3X0D-A nrPDB Length = 655 Score = 34.0 bits (76), Expect = 0.061, Method: Composition-based stats. Identities = 19/47 (40%), Positives = 26/47 (55%), Gaps = 1/47 (2%) Query: 53 LETPEFSGDGAHALSRRSVLELGSGTGAVGLMAATLGADVVVTDLEE 99 L+T + + VL++G+GTG + LMAA GAD VT LE Sbjct: 58 LKTTIAEKKHENTDGKVHVLDIGTGTGLLSLMAAREGAD-KVTALEV 103 >5DST-A nrPDB Length = 332 Score = 33.2 bits (74), Expect = 0.083, Method: Composition-based stats. Identities = 13/39 (33%), Positives = 18/39 (46%) Query: 53 LETPEFSGDGAHALSRRSVLELGSGTGAVGLMAATLGAD 91 L H + VL++GSGTG + + AA GA Sbjct: 35 LTYRNSMYHNKHVFKDKVVLDVGSGTGILSMFAAKAGAK 73 >1WY7-A nrPDB Length = 207 Score = 33.2 bits (74), Expect = 0.089, Method: Composition-based stats. Identities = 21/80 (26%), Positives = 36/80 (45%), Gaps = 10/80 (12%) Query: 65 ALSRRSVLELGSGTGAVGLMAATLGAD--VVVTDLEELQDLLKMNINMNKHLVTGSVQAK 122 + + V +LG+GTG + A LGA + V +E D+L N+ G + K Sbjct: 47 DIEGKVVADLGAGTGVLSYGALLLGAKEVICVEVDKEAVDVLIENL--------GEFKGK 98 Query: 123 VLKWGEEIEGFPSPPDFILM 142 + ++ F S D ++M Sbjct: 99 FKVFIGDVSEFNSRVDIVIM 118 >5FUB-A nrPDB Length = 337 Score = 33.2 bits (74), Expect = 0.094, Method: Composition-based stats. Identities = 25/97 (25%), Positives = 41/97 (42%), Gaps = 9/97 (9%) Query: 65 ALSRRSVLELGSGTGAVGLMAATLG--ADVVVTDLEELQDLLKMNINMNKHLVTGSVQAK 122 AL + VL+LG GTG + L A L A V + + + + + N Sbjct: 42 ALREKVVLDLGCGTGVISLFCALLAKPAGVYAVEASSMAEHTEELVKQN----GCDGVVT 97 Query: 123 VLKWGEEIEGFPSPPDFIL---MADCIYYEESLEPLL 156 V + E P+ D ++ M +C+ +E LE +L Sbjct: 98 VFQERAENLTLPTKVDVLVSEWMGNCLLFEYMLESVL 134 >1WS6-A nrPDB Length = 171 Score = 32.8 bits (73), Expect = 0.12, Method: Composition-based stats. Identities = 26/84 (30%), Positives = 37/84 (44%), Gaps = 1/84 (1%) Query: 27 VLRLQQYSSGGVGCVVWDAAIVLSKYLETPEFSGDGAHALSRRSVLELGSGTGAVGLMAA 86 V+R+ + GV V +A L F R L+ +G+GAVGL AA Sbjct: 1 VVRILGGKARGVALKVPASARPSPVRLRKALFDYLRLRYPRRGRFLDPFAGSGAVGLEAA 60 Query: 87 TLGAD-VVVTDLEELQDLLKMNIN 109 + G + V+V E LLK N+ Sbjct: 61 SEGWEAVLVEKDPEAVRLLKENVR 84 >3Q7E-A nrPDB Length = 349 Score = 32.8 bits (73), Expect = 0.13, Method: Composition-based stats. Identities = 32/123 (26%), Positives = 49/123 (39%), Gaps = 9/123 (7%) Query: 53 LETPEFSGDGAHALSRRSVLELGSGTGAVGLMAATLGA-DVVVTDLEELQDLLKMNINMN 111 L H + VL++GSGTG + + AA GA V+ + + D + N Sbjct: 52 LTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKAN 111 Query: 112 KH-LVTGSVQAKVLKWGEEIEGFPSPPDFIL---MADCIYYEESLEPLLKTLKDISGFET 167 K V ++ KV EE+E D I+ M C++YE L +L + Sbjct: 112 KLDHVVTIIKGKV----EEVELPVEKVDIIISEWMGYCLFYESMLNTVLHARDKWLAPDG 167 Query: 168 CII 170 I Sbjct: 168 LIF 170 >4HGY-A nrPDB Length = 276 Score = 32.4 bits (72), Expect = 0.15, Method: Composition-based stats. Identities = 29/153 (18%), Positives = 56/153 (36%), Gaps = 10/153 (6%) Query: 69 RSVLELGSGTGAVGLMAATLGADV-VVTDLEELQDLLKMNINMNKHLVTGSVQAKVLKWG 127 R VLELG GTG V A LG +V V E + D L+ + G++ VL Sbjct: 64 RPVLELGVGTGRVAFPLADLGVEVHGVESSEPMLDKLREKAAAHP---NGNLVVPVLGNF 120 Query: 128 EEIEGFPSPPDFILMA----DCIYYEESLEPLLKTLKDISGFETCIICCYEQRTMGKNPE 183 +++ + A C+ ++ ++ +++ + G+ Sbjct: 121 AKLDLGEQRYSVVFAAFNTLFCLLGQDEQIDCMRQARELLEPGGTFVVQCL-NPAGQRLA 179 Query: 184 IEKKYFELLQLDFDFEKIPLEKHDEEYRSEDIH 216 + ++L+ + KHD ++ H Sbjct: 180 TGNTF-GTVELEDTAVHLEASKHDPLAQTLSAH 211 >5BP9-A nrPDB Length = 281 Score = 32.4 bits (72), Expect = 0.16, Method: Composition-based stats. Identities = 22/115 (19%), Positives = 45/115 (39%), Gaps = 16/115 (13%) Query: 61 DGAHALSRRSVLELGSGTGAVGLMAATLGADVVVTD-LEELQDLLKMNINMNKHLVTGSV 119 A A++ ++L++G+G+G L G +V D +++K+ + V Sbjct: 95 RTALAMATGTILDVGAGSGCHALALQESGKEVSAIDISPLSVEVMKLRGVKDARQVN--- 151 Query: 120 QAKVLKWGEEIEGFPSPPDFIL----MADCIYYEESLEPLLKTLKDISGFETCII 170 E F + D IL + I E++ + +K + + CI+ Sbjct: 152 --------LFDERFAATFDTILMLMNGSGIIGRLENMPLFFRKMKQLLRPDGCIL 198 >3M70-A nrPDB Length = 286 Score = 32.1 bits (71), Expect = 0.22, Method: Composition-based stats. Identities = 23/103 (22%), Positives = 37/103 (35%), Gaps = 9/103 (8%) Query: 61 DGAHALSRRSVLELGSGTGAVGLMAATLGADVVVTD-LEELQDLLKMNINMNKHLVTGSV 119 D A +S VL+LG G G L + LG DV D E L ++ ++ Sbjct: 114 DAAKIISPCKVLDLGCGQGRNSLYLSLLGYDVTSWDHNENSIAFLNETKEKENLNISTAL 173 Query: 120 QAKVLKWGEEIEGFPSPPDFILMADCIYY--EESLEPLLKTLK 160 + DFI+ + E + ++K +K Sbjct: 174 ------YDINAANIQENYDFIVSTVVFMFLNRERVPSIIKNMK 210 >3CCF-A nrPDB Length = 279 Score = 31.7 bits (70), Expect = 0.27, Method: Composition-based stats. Identities = 22/88 (25%), Positives = 34/88 (38%), Gaps = 12/88 (13%) Query: 28 LRLQQYSSGGVGCVVWDAAIVLSKYLETPEFSGDGAHAL-------SRRSVLELGSGTGA 80 L Q ++ G WDA + Y + F L +L+LG GTG Sbjct: 15 LYFQGMTNLGTAKNFWDATL----YQDKHSFVWQYGEDLLQLLNPQPGEFILDLGCGTGQ 70 Query: 81 VGLMAATLGADVVVTD-LEELQDLLKMN 107 + A GA+V+ TD + + + N Sbjct: 71 LTEKIAQSGAEVLGTDNAATMIEKARQN 98 >4LWO-B nrPDB Length = 368 Score = 31.7 bits (70), Expect = 0.27, Method: Composition-based stats. Identities = 21/87 (24%), Positives = 41/87 (47%), Gaps = 4/87 (4%) Query: 31 QQYSSGGVGCVVWDAAIVLSKYLETPEFSGDGAHALSRRSVLELGSGTGAVGLMAATLGA 90 + YS V ++ + A +S Y ++ E S ++ + V+++GSGTG + + AA GA Sbjct: 22 ESYSDLAVHRLMLEDAQRMSFYRKSIEQSA----SIEGKVVVDVGSGTGILSMWAARAGA 77 Query: 91 DVVVTDLEELQDLLKMNINMNKHLVTG 117 V + ++ + + L T Sbjct: 78 KHVFSIEASSLSEFQIGVVEDNDLSTK 104 >4KRI-A nrPDB Length = 433 Score = 31.7 bits (70), Expect = 0.29, Method: Composition-based stats. Identities = 35/216 (16%), Positives = 70/216 (32%), Gaps = 19/216 (8%) Query: 19 VLEKRDGTVLRLQQYSSGGVGCVVW---DAAIVLSKYLETPEFSGDGAHALSRRSVLELG 75 V+ RD L QY+ G+ W + I + + + + +L++G Sbjct: 173 VVSFRD--FLDRTQYTDTGIFAYEWIFGNNFISPGGWNQNLAILKRFGPMKTGQRMLDIG 230 Query: 76 SGTGAVGLMAAT-LGADVVVTDLE-ELQDLLKMNINMNKHLVTGSVQAKVLKWGEEIEGF 133 G G AA+ G V DL + + ++ K ++ E Sbjct: 231 VGIGGGARQAASEFGLQVHGVDLSTNMLAVALERVHKEKDARVTYAVCDACEYEFE---- 286 Query: 134 PSPPDFILMADCIYYEESLEPLLKTLKDISGFETCIICCYEQRTMGKNPEI--EKKYFEL 191 P+ D++ DCI + + + L + ++ G E + Sbjct: 287 PNSFDYVFSRDCIQHIKDTDKLFSRIYRALKPGGKVL----ITMYGVGHGTLSESFKEYV 342 Query: 192 LQLDFDFEKIPLEKHDEEYRSEDIHIIYIRKKKSKF 227 Q + + LE+ +E + I + +F Sbjct: 343 SQRQYYLKN--LEQIEEIAKKTGFIDIEVENMTPRF 376 >6OGN-A nrPDB Length = 692 Score = 30.9 bits (68), Expect = 0.43, Method: Composition-based stats. Identities = 12/21 (57%), Positives = 17/21 (80%) Query: 71 VLELGSGTGAVGLMAATLGAD 91 VL++G+GTG + +MA T GAD Sbjct: 68 VLDIGTGTGLLSMMAVTAGAD 88 >3EGE-A nrPDB Length = 261 Score = 30.9 bits (68), Expect = 0.46, Method: Composition-based stats. Identities = 29/157 (18%), Positives = 56/157 (35%), Gaps = 19/157 (12%) Query: 66 LSRRSVL-ELGSGTGAVGLMAATLGADVVVTDLEELQDLLKMNINMNKHLVTGSVQAKVL 124 L + SV+ ++G+GTG + A G V + + H Sbjct: 32 LPKGSVIADIGAGTGGYSVALANQGLFVYAVEPSIVMRQ-----QAVVHPQVEWFT---- 82 Query: 125 KWGEEIEGFPSPPDFILMADCIYYEESLEPLLKTLKDISGFETCIICCYEQRTMGKNPEI 184 + E + D ++ I++ LE + ++ I T ++ ++ R + Sbjct: 83 GYAENLALPDKSVDGVISILAIHHFSHLEKSFQEMQRIIRDGTIVLLTFDIRLAQRIWLY 142 Query: 185 EKKYF------ELLQLDFDFEKIPLEKHDEEYRSEDI 215 + F L LD E+I L + + + R E I Sbjct: 143 DYFPFLWEDALRFLPLD---EQINLLQENTKRRVEAI 176 >2I6G-A nrPDB Length = 199 Score = 30.5 bits (67), Expect = 0.54, Method: Composition-based stats. Identities = 25/126 (19%), Positives = 38/126 (30%), Gaps = 13/126 (10%) Query: 51 KYL-ETPEFSGDGAHALSRRSV------LELGSGTGAVGLMAATLGADVVVTDLEELQDL 103 Y E + + L+ V L+LG G G L A G DV D Sbjct: 8 NYFTEKYGLTRTHSDVLAAAKVVAPGRTLDLGCGNGRNSLYLAANGYDVTAWDKNPASMA 67 Query: 104 LKMNINMNKHLVTGSVQAKVLKWGEEIEGFPSPPDFILMADCIYYEE--SLEPLLKTLKD 161 I + L L F DFIL + + E ++ L+ ++ Sbjct: 68 NLERIKAAEGLDNLQTDLVDL----NTLTFDGEYDFILSTVVMMFLEAQTIPGLIANMQR 123 Query: 162 ISGFET 167 + Sbjct: 124 CTKPGG 129 >5WP4-A nrPDB Length = 491 Score = 30.1 bits (66), Expect = 0.70, Method: Composition-based stats. Identities = 36/192 (18%), Positives = 59/192 (30%), Gaps = 19/192 (9%) Query: 14 RSFVRVLEKRDGTVLRLQQYSSGGV--GCVVWDAAIVLSKYLETPEFSGDGAHALSRRSV 71 R F R L+ QY S G+ V+ V + LET + + + + V Sbjct: 235 RGFQRFLDN--------VQYKSSGILRYERVFGQGFVSTGGLETTKEFVEKMNLKPGQKV 286 Query: 72 LELGSGTGAVGL-MAATLGADVVVTDLEE-LQDLLKMNINMNKHLVTGSVQAKVLKWGEE 129 L++G G G MA VV DL + + + Sbjct: 287 LDVGCGIGGGDFYMAEKFDVHVVGIDLSVNMISFALE--RAIGLSCSVEFEVADCTTKHY 344 Query: 130 IEGFPSPPDFILMADCIYYEESLEPLLKTLKDISGFETCIICCYEQRTMGKNPEIEKKYF 189 + D I D I + + L +T ++ R+ K P E Sbjct: 345 PDN---SFDVIYSRDTILHIQDKPALFRTFFKWLKPGGKVLISDYCRS-PKTPSAE-FSE 399 Query: 190 ELLQLDFDFEKI 201 + Q +D + Sbjct: 400 YIKQRGYDLHDV 411 >3E05-A nrPDB Length = 204 Score = 29.7 bits (65), Expect = 1.0, Method: Composition-based stats. Identities = 23/136 (16%), Positives = 48/136 (35%), Gaps = 6/136 (4%) Query: 28 LRLQQYSSGGVGCVVWDAAIVLSKYLETPEFSGDGAHALSRRSVLELGSGTGAVGLMAAT 87 + L QY G+ + A L E + + ++G+G+ +V + A+ Sbjct: 1 MSLAQYPVIGIDDDEFATAKKLITKQEVRAVTLSKLRLQDDLVMWDIGAGSASVSIEASN 60 Query: 88 L---GADVVVTDLEELQDLLKMNINMNKHLVTGSVQAKVLKWGEEIEGFPSPPDFILMAD 144 L G + + ++ N+ V +V E ++ P P + Sbjct: 61 LMPNGRIFALERNPQYLGFIRDNLKK---FVARNVTLVEAFAPEGLDDLPDPDRVFIGGS 117 Query: 145 CIYYEESLEPLLKTLK 160 EE ++ + + LK Sbjct: 118 GGMLEEIIDAVDRRLK 133 >4L7V-A nrPDB Length = 225 Score = 29.7 bits (65), Expect = 1.1, Method: Composition-based stats. Identities = 24/79 (30%), Positives = 35/79 (44%), Gaps = 9/79 (11%) Query: 66 LSRRSVLELGSGTGAVGLMAATLGADV-VVTDLEELQDLLKMNINMNKHLVTGSVQAKVL 124 VLE+G+G+G + A L V V ++ LQ K + K L +V K Sbjct: 91 TPETKVLEIGTGSGYQTAVLAKLVNHVFTVERIKTLQWDAKRRL---KQLDIYNVSTKH- 146 Query: 125 KWGEEIEGFP--SPPDFIL 141 G+ +G+P P D IL Sbjct: 147 --GDGWQGWPARGPFDAIL 163 >6GXV-A nrPDB Length = 484 Score = 29.7 bits (65), Expect = 1.1, Method: Composition-based stats. Identities = 8/33 (24%), Positives = 13/33 (39%), Gaps = 2/33 (6%) Query: 118 SVQAKVLKWGEEIEGFPSPPDFILMADCIYYEE 150 +Q K W + E D+++ AD Y Sbjct: 179 QIQGKAWDWEVDSEN--GNYDYLMGADIDYDHP 209 >1DUS-A nrPDB Length = 194 Score = 29.4 bits (64), Expect = 1.3, Method: Composition-based stats. Identities = 13/44 (29%), Positives = 20/44 (45%), Gaps = 1/44 (2%) Query: 71 VLELGSGTGAVGLMAATLGADVVVTDL-EELQDLLKMNINMNKH 113 +L+LG G G +G+ A + D+ L K NI +N Sbjct: 56 ILDLGCGYGVIGIALADEVKSTTMADINRRAIKLAKENIKLNNL 99 >4NIF-A nrPDB Length = 333 Score = 29.0 bits (63), Expect = 1.6, Method: Composition-based stats. Identities = 19/98 (19%), Positives = 35/98 (35%), Gaps = 7/98 (7%) Query: 39 GCVVWDAAIVLSKYLETPEFSGDGAHALSRRSVLELGSGTGAVGLMAATLGADVVVTDLE 98 GC +W I+L L +G + +GSG + G + T E Sbjct: 186 GCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTLS------GGNWN-TVSE 238 Query: 99 ELQDLLKMNINMNKHLVTGSVQAKVLKWGEEIEGFPSP 136 +DL+ ++++ H + Q W + + P Sbjct: 239 TAKDLVSKMLHVDPHQRLTAKQVLQHPWVTQKDKLPQS 276 >4AJU-A nrPDB Length = 387 Score = 29.0 bits (63), Expect = 1.7, Method: Composition-based stats. Identities = 14/100 (14%), Positives = 37/100 (37%), Gaps = 5/100 (5%) Query: 134 PSPPDFILMADCIYYEESLEPLLKTL-----KDISGFETCIICCYEQRTMGKNPEIEKKY 188 P+ + + LL +L + +S + + K+ ++++ + Sbjct: 98 PTETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETF 157 Query: 189 FELLQLDFDFEKIPLEKHDEEYRSEDIHIIYIRKKKSKFP 228 F L + FD E +P+ + ++ ++ + K P Sbjct: 158 FNLSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIP 197 >4R0V-A nrPDB Length = 514 Score = 29.0 bits (63), Expect = 2.0, Method: Composition-based stats. Identities = 14/55 (25%), Positives = 21/55 (38%), Gaps = 1/55 (1%) Query: 114 LVTGSVQAKVLKWGEEIEGFPSPPDFILMADCIYYEESLEPLLKTLKDI-SGFET 167 L G+ K L G GF D + AD EE E L + + + + + Sbjct: 105 LAPGATTPKQLAEGLRRLGFDEVFDTLFGADLTIMEEGSELLHRLTEHLEAHPHS 159 >2B3T-A nrPDB Length = 276 Score = 28.6 bits (62), Expect = 2.2, Method: Composition-based stats. Identities = 20/79 (25%), Positives = 34/79 (43%), Gaps = 11/79 (13%) Query: 70 SVLELGSGTGAVGLMAATLGAD---VVVTDLEELQDLLKMNINMNKHLVTGSVQAKVLKW 126 +L+LG+GTGA+ L A+ D + V + + L + N HL ++ W Sbjct: 112 RILDLGTGTGAIALALASERPDCEIIAVDRMPDAVSLAQRNAQ---HLAIKNIHILQSDW 168 Query: 127 -----GEEIEGFPSPPDFI 140 G++ S P +I Sbjct: 169 FSALAGQQFAMIVSNPPYI 187 >6IFX-A nrPDB Length = 287 Score = 28.6 bits (62), Expect = 2.2, Method: Composition-based stats. Identities = 24/127 (18%), Positives = 51/127 (40%), Gaps = 4/127 (3%) Query: 61 DGAHALSRRSVLELGSGTGAVGLMAATLGADVVVTDLEE-LQDLLKMNINMNKHLVTGSV 119 D A + V+E+G G GA+ A VV ++++ L +LK ++ +++ Sbjct: 42 DHAEVTEKTGVIEIGPGIGALTEQLAKRAKKVVAFEIDQRLLPILKDTLSPYENVTVIHQ 101 Query: 120 QA-KVLKWGEEIEGFPSPPDFILMADCIYYEESLEPLLKTL-KDISGFETCIICCYEQRT 177 K E F + +++A+ YY + ++K L + + ++ E Sbjct: 102 DVLKADVKSVIEEQFQDCDEIMVVANLPYY-VTTPIIMKLLEEHLPLKGIVVMLQKEVAE 160 Query: 178 MGKNPEI 184 N + Sbjct: 161 RMANTKR 167 >6IFV-A nrPDB Length = 215 Score = 28.6 bits (62), Expect = 2.3, Method: Composition-based stats. Identities = 27/143 (18%), Positives = 58/143 (40%), Gaps = 5/143 (3%) Query: 61 DGAHALSRRSVLELGSGTGAVGLMAATLGADVVVTDLEE-LQDLLKMNINMNKHLVTGSV 119 D A + V+E+G G GA+ A VV ++++ L +LK ++ +++ Sbjct: 42 DHAEVTEKTGVIEIGPGIGALTEQLAKRAKKVVAFEIDQRLLPILKDTLSPYENVTVIHQ 101 Query: 120 QA-KVLKWGEEIEGFPSPPDFILMADCIYYEESLEPLLKTL-KDISGFETCIICCYE-QR 176 K E F + +++A+ YY + ++K L + + ++ E Sbjct: 102 DVLKADVKSVIEEQFQDCDEIMVVANLPYY-VTTPIIMKLLEEHLPLKGIVVMLQKEVAE 160 Query: 177 TMGKNPEIEKKYFELLQLDFDFE 199 M +P ++ + + F E Sbjct: 161 RMAADPSSKEYGSLSIAVQFYTE 183 >3K89-A nrPDB Length = 314 Score = 28.6 bits (62), Expect = 2.6, Method: Composition-based stats. Identities = 16/51 (31%), Positives = 22/51 (43%), Gaps = 1/51 (1%) Query: 61 DGAHALSRRSVLELGSGTGAVGLMAATLGADVVVTDLEELQDLLKMNINMN 111 DGAH + R + VG MAA LGA+ V LE + + + Sbjct: 111 DGAHLVRLRGQFMQAAAPAGVGAMAAVLGAEDAVV-LEVCAEAAGSQVVVP 160 >5AH0-A nrPDB Length = 387 Score = 28.2 bits (61), Expect = 2.7, Method: Composition-based stats. Identities = 31/155 (20%), Positives = 56/155 (36%), Gaps = 17/155 (10%) Query: 43 WDAAIVLSKYLETPEFSGDGAHAL---------------SRRSVLELGSGTGAVGLMAAT 87 WD A L Y++ AH+ L + L+A + Sbjct: 55 WDRACELYAYIKGGTVDYGHAHSTQKGHSRYGRTYPGLYPEWGNLTTEGKVNKIHLVAHS 114 Query: 88 LGADVVVTDLEELQDLLKMNINMNKHLVTGSVQAKVLKWGEEIEGFPSPPDFILMADCI- 146 +G V T ++ L++ + N ++ S+ A W I SP D +AD I Sbjct: 115 MGGQTVRTLVQLLKEGSEEERNTTPSQLS-SLFAGGKSWVHSITTIASPHDGTTLADGIN 173 Query: 147 YYEESLEPLLKTLKDISGFETCIICCYEQRTMGKN 181 + + + L+ +L +G +I ++ G N Sbjct: 174 IFGDFAKNLVASLASFTGAGEKLIYDFKLDQWGLN 208 >2YXE-A nrPDB Length = 215 Score = 28.2 bits (61), Expect = 3.1, Method: Composition-based stats. Identities = 12/48 (25%), Positives = 21/48 (43%), Gaps = 4/48 (8%) Query: 67 SRRSVLELGSGTGA-VGLMAATLGAD---VVVTDLEELQDLLKMNINM 110 VLE+G+G G + A +G D V + + EL + + + Sbjct: 77 PGMKVLEIGTGCGYHAAVTAEIVGEDGLVVSIERIPELAEKAERTLRK 124 >5YYS-A nrPDB Length = 949 Score = 28.2 bits (61), Expect = 3.1, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 29/73 (39%), Gaps = 12/73 (16%) Query: 30 LQQYSSGGVGCVVWDAAIVLSKY-----------LETPEFSGDGAHALSRRSVLELGSGT 78 LQ Y G + AA+ L+ + LE ++ + + GSG Sbjct: 657 LQDYKKIGSPFSIPKAALSLAGFAPAFSAVSYASLEEQLKDFGAGIEVTLLAAIPAGSGL 716 Query: 79 GAVGLMAAT-LGA 90 G ++A+T LGA Sbjct: 717 GTSSILASTVLGA 729 >2YVL-A nrPDB Length = 248 Score = 27.8 bits (60), Expect = 3.7, Method: Composition-based stats. Identities = 10/45 (22%), Positives = 20/45 (44%), Gaps = 1/45 (2%) Query: 67 SRRSVLELGSGTG-AVGLMAATLGADVVVTDLEELQDLLKMNINM 110 + VLE G+G+G + +++ G +EE + N+ Sbjct: 91 KEKRVLEFGTGSGALLAVLSEVAGEVWTFEAVEEFYKTAQKNLKK 135 >3GRP-A nrPDB Length = 266 Score = 27.4 bits (59), Expect = 5.3, Method: Composition-based stats. Identities = 20/89 (22%), Positives = 34/89 (38%), Gaps = 2/89 (2%) Query: 23 RDGTVLRLQQYSSGGVGCVVWDAAIVLSKYLETPEFSGDGAHALSRRSVLELGSGTGAVG 82 RDG +R+Q V V AA L++ L ++ S++ + G Sbjct: 113 RDGLFVRMQDQDWDDVLAVNLTAASTLTRELIHSMMRRRYGRIINITSIVGVVGNPGQTN 172 Query: 83 LMAATLGADVVVTDLEELQDLLKMNINMN 111 AA G ++ Q++ NI +N Sbjct: 173 YCAAKAG--LIGFSKALAQEIASRNITVN 199 >3HZZ-A nrPDB Length = 467 Score = 27.0 bits (58), Expect = 6.5, Method: Composition-based stats. Identities = 12/34 (35%), Positives = 16/34 (47%) Query: 53 LETPEFSGDGAHALSRRSVLELGSGTGAVGLMAA 86 LET + + L V ELG G V +MA+ Sbjct: 65 LETRDKDPRKSIHLDEVPVPELGPGEALVAVMAS 98 >1L2L-A nrPDB Length = 457 Score = 26.7 bits (57), Expect = 9.6, Method: Composition-based stats. Identities = 27/122 (22%), Positives = 45/122 (36%), Gaps = 7/122 (5%) Query: 38 VGCVVWDAAIVLSKYLETPEFSGDGAHALSRRSVLELGSGTGAVGLMAATLGADVVVTDL 97 +G ++W +I K E S + + + EL G G VG+MA LG V + Sbjct: 77 LGSILW--SIKRGKAAELLVVSREVREYMRKWGWDELRMG-GQVGIMANLLGG---VYGI 130 Query: 98 EELQDLLKMNINMNKHLVTGSVQAKVLKWGEEIEGFPSPPDFILMADCIYYEESLEPLLK 157 + + +++ + G + + GE P DCI+Y K Sbjct: 131 PVIAHVPQLSELQASLFLDGPIYVPTFERGELRLIHPREFRKG-EEDCIHYIYEFPRNFK 189 Query: 158 TL 159 L Sbjct: 190 VL 191 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.125 0.315 Lambda K H 0.267 0.0385 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 7,865,779 Number of Sequences: 36641 Number of extensions: 291935 Number of successful extensions: 1040 Number of sequences better than 10.0: 53 Number of HSP's better than 10.0 without gapping: 49 Number of HSP's successfully gapped in prelim test: 37 Number of HSP's that attempted gapping in prelim test: 968 Number of HSP's gapped (non-prelim): 88 length of query: 229 length of database: 10,336,785 effective HSP length: 94 effective length of query: 135 effective length of database: 6,892,531 effective search space: 930491685 effective search space used: 930491685 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.5 bits) S2: 57 (26.7 bits)