BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= Q9H4Y5 (243 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3QAG-A nrPDB 489 e-139 3LFL-A nrPDB 327 3e-90 3WD6-A nrPDB 143 8e-35 3RBT-A nrPDB 113 9e-26 4QQ7-A nrPDB 98 3e-21 4CHS-A nrPDB 71 5e-13 2VO4-A nrPDB 71 5e-13 4PQI-A nrPDB 66 1e-11 5G5A-A nrPDB 64 8e-11 4AGS-A nrPDB 62 3e-10 5ECL-B nrPDB 61 4e-10 5IQY-A nrPDB 59 1e-09 2CZ2-A nrPDB 59 2e-09 6EP7-A nrPDB 57 7e-09 1FW1-A nrPDB 57 9e-09 5D9W-A nrPDB 55 3e-08 5J5N-A nrPDB 55 4e-08 5ELG-A nrPDB 54 8e-08 4J2F-A nrPDB 52 3e-07 5LOL-A nrPDB 51 4e-07 6JWK-A nrPDB 49 2e-06 1E6B-A nrPDB 49 3e-06 3UBL-A nrPDB 48 4e-06 3PR8-A nrPDB 47 5e-06 4MK3-A nrPDB 47 6e-06 4IGJ-A nrPDB 45 4e-05 1GWC-A nrPDB 44 6e-05 5N9U-A nrPDB 44 7e-05 3M8N-A nrPDB 44 8e-05 5NR1-A nrPDB 43 1e-04 4MDC-A nrPDB 43 2e-04 3TOT-A nrPDB 42 3e-04 3IBH-A nrPDB 41 4e-04 2JL4-A nrPDB 39 0.001 3M3M-A nrPDB 39 0.002 3R2Q-A nrPDB 39 0.003 3NIV-A nrPDB 38 0.004 1OYJ-A nrPDB 38 0.004 2PVQ-A nrPDB 38 0.005 3BBY-A nrPDB 37 0.006 2GDR-A nrPDB 37 0.009 4PXO-A nrPDB 36 0.016 2PMT-A nrPDB 35 0.042 5F05-A nrPDB 34 0.059 1AW9-A nrPDB 34 0.070 3UAR-A nrPDB 34 0.073 1TU7-A nrPDB 33 0.085 5D73-A nrPDB 33 0.12 5F06-A nrPDB 33 0.16 4PTS-A nrPDB 32 0.20 5F07-A nrPDB 31 0.56 3GRX-A nrPDB 31 0.60 3M1G-A nrPDB 29 1.6 2D2Z-A nrPDB 28 2.5 1N2A-A nrPDB 28 3.0 5W0C-A nrPDB 28 3.3 3C8E-A nrPDB 28 3.7 1AXD-A nrPDB 27 6.6 4TR1-A nrPDB 27 6.7 3J6B-7 nrPDB 27 8.4 >3QAG-A nrPDB Length = 239 Score = 489 bits (1260), Expect = e-139, Method: Compositional matrix adjust. Identities = 233/239 (97%), Positives = 233/239 (97%) Query: 1 MSGDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP 60 MSGDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP Sbjct: 1 MSGDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP 60 Query: 61 EWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELF 120 EWYYTKHPFGHIPVLETSQ QLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELF Sbjct: 61 EWYYTKHPFGHIPVLETSQSQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELF 120 Query: 121 CKVPHLTKECLVALRCGRECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWP 180 KVPHLTKECLVALR GRE TNLKAALRQEFSNLEEILEYQNTTFFGGT ISMIDYLLWP Sbjct: 121 SKVPHLTKECLVALRSGRESTNLKAALRQEFSNLEEILEYQNTTFFGGTSISMIDYLLWP 180 Query: 181 WFERLDVYGILDCVSHTPALRLWISAMKWDPTVCALLMDKSIFQGFLNLYFQNNPNAFD 239 WFERLDVYGILDCVSHTPALRLWISAMKWDPTV ALLMDKSIFQGFLNLYFQNNPNAFD Sbjct: 181 WFERLDVYGILDCVSHTPALRLWISAMKWDPTVSALLMDKSIFQGFLNLYFQNNPNAFD 239 >3LFL-A nrPDB Length = 240 Score = 327 bits (837), Expect = 3e-90, Method: Compositional matrix adjust. Identities = 154/242 (63%), Positives = 187/242 (77%), Gaps = 2/242 (0%) Query: 1 MSGDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP 60 MSG++ R+LGKGS PPGPVPEG IRIYSMRFCP++ RTRLVLKAK IRHEV+NINL+NKP Sbjct: 1 MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKP 60 Query: 61 EWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELF 120 EW++ K+PFG +PVLE SQ QLIYES I CEYLD+AYPG+KL P DPYE+A QKM+LELF Sbjct: 61 EWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELF 120 Query: 121 CKVPHLTKECLVALRCGRECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWP 180 KVP L + + + LK R+EF+ L E+L + TTFFGG ISMIDYL+WP Sbjct: 121 SKVPSLVG-SFIRSQNKEDYAGLKEEFRKEFTKL-EVLTNKKTTFFGGNSISMIDYLIWP 178 Query: 181 WFERLDVYGILDCVSHTPALRLWISAMKWDPTVCALLMDKSIFQGFLNLYFQNNPNAFDF 240 WFERL+ + +CV HTP L+LW++AMK DPTV ALL + +QGFL LY QN+P A D+ Sbjct: 179 WFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDY 238 Query: 241 GL 242 GL Sbjct: 239 GL 240 >3WD6-A nrPDB Length = 256 Score = 143 bits (360), Expect = 8e-35, Method: Compositional matrix adjust. Identities = 85/238 (35%), Positives = 125/238 (52%), Gaps = 13/238 (5%) Query: 6 TRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYT 65 T+ L KG P P G +R+Y+MR+CPY+ RT L L AK I +EVVNI+L +KPEW T Sbjct: 14 TKHLRKGD--PLPPFNGKLRVYNMRYCPYAQRTILALNAKQIDYEVVNIDLIDKPEWLTT 71 Query: 66 KHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPH 125 K F +P +E ++ IYES++ EYLD+ YP R L P DP ++A K+++E + Sbjct: 72 KSAFAKVPAIEIAEDVTIYESLVTVEYLDEVYPKRPLLPQDPLKKALDKIIVEASAPIQS 131 Query: 126 LTKECLVALRCGRECTNLK--AALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFE 183 L + + + N + AA + ++E L+ + T F G+ DY++WPWFE Sbjct: 132 L----FIKILKFSDTVNEEHVAAYHKALDFIQEQLKNRGTVFLDGSEPGYADYMIWPWFE 187 Query: 184 RLDVYGILDCVSHTPA----LRLWISAMKWDPTVCALLMDKSIFQGFLNLYFQNN-PN 236 RL + + V P+ L +I M D V L+ I F Y + PN Sbjct: 188 RLRAFAHDERVRLEPSKYSLLLEYIDNMLKDSAVSQYLIPLEILAKFHEAYTKKERPN 245 >3RBT-A nrPDB Length = 246 Score = 113 bits (282), Expect = 9e-26, Method: Compositional matrix adjust. Identities = 74/224 (33%), Positives = 110/224 (49%), Gaps = 23/224 (10%) Query: 3 GDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEW 62 G ++ G PP P +R+Y + PY HR LVL+AK I++EV ++ PEW Sbjct: 7 GTYFHSVNAGVIPP-PALTDKLRLYHVDMNPYGHRVLLVLEAKRIKYEVYRLDPLRLPEW 65 Query: 63 YYTKHPFGHIPVLETSQCQ---LIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLEL 119 + K+P IPVLE Q ++ESV+ C+YLD+ Y L +DPY +A+ ++L+E Sbjct: 66 FRAKNPRLKIPVLEIPTDQGDRFLFESVVICDYLDEKYTRHTLHSHDPYVKAQDRLLIER 125 Query: 120 FCKVPHLTKECL-VALRCGRECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLL 178 F ++ + EC G E + Q E+ L + T +FGG M+DY++ Sbjct: 126 FNELIKGSLECFDTNFAFGSE------QIIQTLEIFEKELTNRGTNYFGGNRPGMLDYMV 179 Query: 179 WPWFERLDVYGILDCVSHT---------PALRLWISAMKWDPTV 213 WPW ERL +L CV+ P W M+ D V Sbjct: 180 WPWVERL---YLLRCVNDRKFVEKKSLFPNFADWGDQMQLDDIV 220 >4QQ7-A nrPDB Length = 207 Score = 97.8 bits (242), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 63/187 (33%), Positives = 95/187 (50%), Gaps = 10/187 (5%) Query: 20 PEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQ 79 P ++ +YS CP+S R RLVL K + E+ +++L NKPE +P+G +P+L + Sbjct: 2 PGSMMVLYSGTTCPFSQRCRLVLFEKGMDFEIRDVDLFNKPEDISVMNPYGQVPIL-VER 60 Query: 80 CQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLL-----ELFCKVPHLTKECLVAL 134 ++YES I EY+D+ +P +L P DP +RAR ++ L ELF V L E A Sbjct: 61 DLILYESNIINEYIDERFPHPQLMPADPVQRARARLFLLNFEKELFVHVSTLENEKGKAA 120 Query: 135 RCGRECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCV 194 E L A+R + L I + + G SM+D + P RLD YGI Sbjct: 121 EKNHEKARL--AIRDRLTQLAPI--FVKNKYMLGEEFSMLDVAIAPLLWRLDHYGIELSK 176 Query: 195 SHTPALR 201 + P ++ Sbjct: 177 NAAPLMK 183 >4CHS-A nrPDB Length = 219 Score = 70.9 bits (172), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 56/180 (31%), Positives = 88/180 (48%), Gaps = 15/180 (8%) Query: 32 CPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPF-GHIPVLETSQCQLIYESVIAC 90 P+ R R+ L K I +E +LRNK +P IPVL + I ES+IA Sbjct: 13 SPFGMRVRIALAEKGIEYEYKEEDLRNKSPLLLQMNPVHKKIPVL-IHNGKPISESLIAV 71 Query: 91 EYLDDAYPGRK-LFPYDPYERARQKMLLE-LFCKVPHLTKECLVALRCGRECTNLKAALR 148 +Y+++ + R L P DPY+RA+ + + + K+ L K+ + G E K A + Sbjct: 72 QYIEEVWNDRNPLLPSDPYQRAQARFWADYVDIKIHDLGKKIWTS--KGEE----KEAAK 125 Query: 149 QEFSNLEEILEYQ--NTTFFGGTCISMIDYLLWP---WFERLDVYGILDCVSHTPALRLW 203 +EF ++LE Q + T+FGG I +D L P WF+ + +G L+ + P W Sbjct: 126 KEFIEALKLLEEQLGDKTYFGGDNIGFVDIALVPFYTWFKVYETFGSLNIENECPRFVAW 185 >2VO4-A nrPDB Length = 219 Score = 70.9 bits (172), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 59/204 (28%), Positives = 96/204 (47%), Gaps = 15/204 (7%) Query: 32 CPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPF-GHIPVLETSQCQLIYESVIAC 90 P+ R R+ L K I++E +LRNK +P IPVL + I ES+IA Sbjct: 13 SPFGMRVRIALAEKGIKYEYKEEDLRNKSPLLLQMNPVHKKIPVL-IHNGKPICESLIAV 71 Query: 91 EYLDDAYPGRK-LFPYDPYERARQKMLLE-LFCKVPHLTKECLVALRCGRECTNLKAALR 148 +Y+++ + R L P DPY+RA+ + + + K+ L ++ + G E K A + Sbjct: 72 QYIEEVWNDRNPLLPSDPYQRAQTRFWADYVDKKIYDLGRKIWTS--KGEE----KEAAK 125 Query: 149 QEFSNLEEILEYQ--NTTFFGGTCISMIDYLLWP---WFERLDVYGILDCVSHTPALRLW 203 +EF ++LE Q + T+FGG + +D L P WF+ + +G L+ S P W Sbjct: 126 KEFIEALKLLEEQLGDKTYFGGDNLGFVDIALVPFYTWFKAYETFGTLNIESECPKFIAW 185 Query: 204 ISAMKWDPTVCALLMDKSIFQGFL 227 +V L D+ F+ Sbjct: 186 AKRCLQKESVAKSLPDQQKVYEFI 209 >4PQI-A nrPDB Length = 241 Score = 66.2 bits (160), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 53/204 (25%), Positives = 93/204 (45%), Gaps = 19/204 (9%) Query: 12 GSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEV--VNINLRNKPEWYYTK-HP 68 QPP + +G ++Y+ CP++ R + K ++ E+ V + L+N+P WY K +P Sbjct: 23 AEQPP--LFDGTTKLYTCYTCPFAQRVWITRNFKGLQDEIKLVPLILQNRPAWYPEKVYP 80 Query: 69 FGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTK 128 +P LE ++ ES+ +YL+ + G L P DP A+++ ELF Sbjct: 81 PNKVPSLE-HNGKITGESLDLIKYLESNFEGPSLLPKDP---AKKEFAEELFSYTDKFNG 136 Query: 129 ECLVALRCGRECTNLKAALRQEFSNLEEIL-EYQNTTFFGGTCISMIDYLLWPWFERLDV 187 A + +L F +LE L ++ + FF G S++D P+ ERL++ Sbjct: 137 TVYTAFKG-----DLAKEAGPAFDHLENALHKFDDGPFFLGKEFSLVDIAYIPFVERLNI 191 Query: 188 YGI----LDCVSHTPALRLWISAM 207 + + D + L WI + Sbjct: 192 FLLEVFKYDITAGRQKLAAWIEEV 215 >5G5A-A nrPDB Length = 221 Score = 63.5 bits (153), Expect = 8e-11, Method: Compositional matrix adjust. Identities = 49/177 (27%), Positives = 83/177 (46%), Gaps = 13/177 (7%) Query: 34 YSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPF-GHIPVLETSQCQLIYESVIACEY 92 + RTR+ L+ K+++ + +L NK +P IPVL + ES+I EY Sbjct: 15 FGMRTRIALEEKNVKFDYREQDLWNKSPILLEMNPVHKKIPVL-IHNGNPVCESLIQIEY 73 Query: 93 LDDAYPGRK-LFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECTNLKAALRQEF 151 +D+ +P + L P DPY+RA+ K + K + + + + G E A ++EF Sbjct: 74 IDEVWPSKTPLLPSDPYQRAQAKFWGDFIDKKVYASARLIWGAK-GEE----HEAGKKEF 128 Query: 152 SNLEEILEYQ--NTTFFGGTCISMIDYLL---WPWFERLDVYGILDCVSHTPALRLW 203 + + LE + + T+FGG +D L + WFE + +G + P L W Sbjct: 129 IEILKTLESELGDKTYFGGETFGYVDIALIGFYSWFEAYEKFGSFSIEAECPKLIAW 185 >4AGS-A nrPDB Length = 471 Score = 61.6 bits (148), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 54/210 (25%), Positives = 89/210 (42%), Gaps = 23/210 (10%) Query: 26 IYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQLIYE 85 +YS FCP+ R RL + + + +V + L +PEWY +P +P L T + ++E Sbjct: 255 LYSNLFCPFVDRARLASELRKFQMHIVEVPLHPQPEWYKYINPRDTVPALFTPSGEAVHE 314 Query: 86 SVIACEYLD-DAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVA--LRCGRECTN 142 S + +Y+D A G L P E+ + + F + L++ +R G + Sbjct: 315 SQLIVQYIDCVATKGSALVPRGDAEKEYE---VGFFVENAGYFVGGLMSWIIRGGEDA-- 369 Query: 143 LKAALRQEFSNLEEILE---YQNTTFFGGTCISMIDYLLWPWFERLDVY-----GILDCV 194 KA L+ LE+ L + FFGG ++ D + P+ R + G D Sbjct: 370 -KAELQWAAGELEQQLAKHPFGEGPFFGGKRMNAGDVAILPFLVRAKAFMPEFSGGYDLF 428 Query: 195 SHTPALRLWISAMKWDPTVCALLMDKSIFQ 224 +H P L A P KS+F+ Sbjct: 429 AHFPLLNGLAEAGMATPEA------KSVFR 452 Score = 51.6 bits (122), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 22/76 (28%), Positives = 44/76 (57%), Gaps = 3/76 (3%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNK-PEWYYTKHPFGHIPVLETSQC-- 80 +++Y CP+ HR +V + K + ++ V + LR + P+WY +P +P LE Sbjct: 27 LKLYVSATCPFCHRVEIVAREKQVSYDRVAVGLREEMPQWYKQINPRETVPTLEVGNADK 86 Query: 81 QLIYESVIACEYLDDA 96 + ++ES++ +YLD++ Sbjct: 87 RFMFESMLIAQYLDNS 102 >5ECL-B nrPDB Length = 223 Score = 61.2 bits (147), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 53/208 (25%), Positives = 87/208 (41%), Gaps = 13/208 (6%) Query: 34 YSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPF-GHIPVLETSQCQLIYESVIACEY 92 + R R+ L+ K + E + NK +P IPVL + + ES+ +Y Sbjct: 21 FGMRARVALREKGVEFEYREEDFSNKSPLLLQSNPIHKKIPVL-VHNGKPVCESLNVVQY 79 Query: 93 LDDAYPGRK-LFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECTNLKAALRQEF 151 +D+A+P + FP DPY RA+ + + F + V + G E + A ++EF Sbjct: 80 VDEAWPEKNPFFPSDPYGRAQARFWAD-FVDKKFTDAQFKVWGKKGEE----QEAGKKEF 134 Query: 152 SNLEEILEYQ--NTTFFGGTCISMIDYLL---WPWFERLDVYGILDCVSHTPALRLWISA 206 +ILE + + +FGG +D L WF+ + +G S +P L W Sbjct: 135 IEAVKILESELGDKPYFGGDSFGYVDISLITFSSWFQAYEKFGNFSIESESPKLIAWAKR 194 Query: 207 MKWDPTVCALLMDKSIFQGFLNLYFQNN 234 +V L D + Y +NN Sbjct: 195 CMEKESVSKSLPDSEKIVAYAAEYRKNN 222 >5IQY-A nrPDB Length = 216 Score = 59.3 bits (142), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 41/156 (26%), Positives = 65/156 (41%), Gaps = 12/156 (7%) Query: 32 CPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQLIYESVIACE 91 CP+S R L L+ K I +E+ ++L NKPEW+ P G +PV + + I +S + + Sbjct: 23 CPFSQRVLLTLEEKKITYEMKLVDLSNKPEWFLKISPEGKVPVFNSGDGKWIADSDVITQ 82 Query: 92 YLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECTNLKAALRQEF 151 +++ +P L Y K+ P K L+ + AL E Sbjct: 83 VIEEKFPTPSLVTPPEYASVGSKIF-------PSFVK----FLKSKDASDGSEKALLDEL 131 Query: 152 SNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDV 187 L+E L+ + G +S D L P L V Sbjct: 132 QALDEHLKAHG-PYISGENVSAADLSLGPKLFHLQV 166 >2CZ2-A nrPDB Length = 223 Score = 58.9 bits (141), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 43/163 (26%), Positives = 75/163 (46%), Gaps = 8/163 (4%) Query: 35 SHRTRLVLKAKDIRHEVVNINL-----RNKPEWYYTKHPFGHIPVLETSQCQLIYESVIA 89 S R R+ L K I +E+V INL + E + T +P +P L+ ++ +S+ Sbjct: 24 SWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITIV-QSLAI 82 Query: 90 CEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECTN--LKAAL 147 EYL++ P +L P DP +RA +M+ +L + V + G+E + + Sbjct: 83 MEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQVGQENQMQWAQKVI 142 Query: 148 RQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGI 190 F+ LE+IL+ + G +SM D L P + + + Sbjct: 143 TSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKV 185 >6EP7-A nrPDB Length = 220 Score = 57.0 bits (136), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 46/177 (25%), Positives = 81/177 (45%), Gaps = 13/177 (7%) Query: 34 YSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPF-GHIPVLETSQCQLIYESVIACEY 92 Y RTR+ L+ K +++E +L NK +P IPVL + + I ES+I +Y Sbjct: 15 YGMRTRIALEEKKVKYEYREEDLSNKSPLLLQMNPIHKKIPVL-IHEGKPICESIIQVQY 73 Query: 93 LDDAYPGRK-LFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECTNLKAALRQEF 151 +D+ +P + P DPY+RA+ + + K ++ + L + E + A + EF Sbjct: 74 IDELWPDTNPILPSDPYQRAQARFWADYIDKKTYVPCKALWS-----ESGEKQEAAKIEF 128 Query: 152 SNLEEILEYQ--NTTFFGGTCISMIDYL---LWPWFERLDVYGILDCVSHTPALRLW 203 + + L+ + + +FGG ++D + WF + L V P L W Sbjct: 129 IEVLKTLDSELGDKYYFGGNEFGLVDIAFIGFYSWFRTYEEVANLSIVLEFPKLMAW 185 >1FW1-A nrPDB Length = 216 Score = 56.6 bits (135), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 43/163 (26%), Positives = 74/163 (45%), Gaps = 8/163 (4%) Query: 35 SHRTRLVLKAKDIRHEVVNINLRNKPEWYYTK-----HPFGHIPVLETSQCQLIYESVIA 89 S R R+ L K I ++ V INL ++K +P +P L+ I++S+ Sbjct: 17 SWRVRIALALKGIDYKTVPINLIKDGGQQFSKDFQALNPMKQVPTLKIDGIT-IHQSLAI 75 Query: 90 CEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRE--CTNLKAAL 147 EYL++ P +L P DP +RA +M+ +L + V + G E T + A+ Sbjct: 76 IEYLEETRPTPRLLPQDPKKRASVRMISDLIAGGIQPLQNLSVLKQVGEEMQLTWAQNAI 135 Query: 148 RQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGI 190 F+ LE+IL+ + G ++M D L P + + + Sbjct: 136 TCGFNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAERFKV 178 >5D9W-A nrPDB Length = 230 Score = 55.1 bits (131), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 41/157 (26%), Positives = 63/157 (40%), Gaps = 14/157 (8%) Query: 32 CPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQLIYESVIACE 91 P+S R L L+ K + +E+ I+++NKP+W+ P G +PV + I +S + + Sbjct: 37 SPFSQRVLLTLEEKKVPYEMKLIDVQNKPDWFLKISPEGKVPVFNGGDGKWIPDSDVITQ 96 Query: 92 YLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVA-LRCGRECTNLKAALRQE 150 +++ YP L Y K+ C L+ + AL E Sbjct: 97 VIEEKYPTPSLVTPPEYASVGSKIF------------SCFTTFLKSKDPNDGSEKALLTE 144 Query: 151 FSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDV 187 LEE L+ F G IS D L P L V Sbjct: 145 LQALEEHLKAHG-PFINGQNISAADLSLAPKLYHLQV 180 >5J5N-A nrPDB Length = 231 Score = 54.7 bits (130), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 45/177 (25%), Positives = 83/177 (46%), Gaps = 15/177 (8%) Query: 32 CPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFG-HIPVLETSQCQLIYESVIAC 90 P+ R RL L K +++E +L NK +P IPVL + + ES+I Sbjct: 25 SPFGMRVRLALAEKGVKYEYSEEDLWNKSALLLQMNPVNKQIPVL-VHNGKPVCESLIIV 83 Query: 91 EYLDDAYPGRK-LFPYDPYERARQKMLLELF-CKVPHLTKECLVALRCGRECTNLKAALR 148 +Y+D+ + L P DPY+RA+ + + K+ L ++ + + G E + A + Sbjct: 84 QYIDEVWKDSAPLLPSDPYQRAQSRFWADFVDKKIYDLGRK--IWTKKGEE----QEAAK 137 Query: 149 QEFSNLEEILEYQ--NTTFFGGTCISMIDYLLWP---WFERLDVYGILDCVSHTPAL 200 ++F + +++E + + +FGG I +D L P WF + G + + P + Sbjct: 138 KDFIDSLKLMEGELGDKPYFGGETIGYVDIALVPFYSWFYAYETIGNFNIEAECPKM 194 >5ELG-A nrPDB Length = 221 Score = 53.5 bits (127), Expect = 8e-08, Method: Compositional matrix adjust. Identities = 40/156 (25%), Positives = 65/156 (41%), Gaps = 12/156 (7%) Query: 32 CPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQLIYESVIACE 91 CP+S R L L+ K + +++ INL +KP+W+ P G +PVL+ + + +S + Sbjct: 20 CPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLKIDD-KWVTDSDVIVG 78 Query: 92 YLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECTNLKAALRQEF 151 L++ YP L K E ++ L+ + AL E Sbjct: 79 ILEEKYPDPPL-----------KTPAEFASVGSNIFGTFGTFLKSKDSNDGSEHALLVEL 127 Query: 152 SNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDV 187 LE L+ + F G +S +D L P L V Sbjct: 128 EALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQV 163 >4J2F-A nrPDB Length = 223 Score = 51.6 bits (122), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 56/216 (25%), Positives = 89/216 (41%), Gaps = 16/216 (7%) Query: 23 LIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPF-GHIPVLETSQCQ 81 +++++ P+S R LK K I +E V +L NK +P IPVL + Sbjct: 4 VLKLHGAWPSPFSCRVIWALKLKGIPYEYVEEDLFNKSPLLLQYNPVHKKIPVL-VHGGK 62 Query: 82 LIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECT 141 I ES I EYLD+ +P L P DP+ERA + ++ K + + Sbjct: 63 PICESTIILEYLDETWPENPLLPSDPHERAVARFWVKFIE-----DKGTAIWNIFRTKGE 117 Query: 142 NLKAALRQEFSNLEEILEY----QNTTFFGGTCISMIDYL---LWPWFERL-DVYGILDC 193 L+ A++ L+ I E+ + +FGG I ++D + W + +V G+ Sbjct: 118 ELEKAVKNCLEVLKTIEEHAMGVSDDKYFGGDKIGIVDIAFCGIAHWLGVIEEVAGVKVL 177 Query: 194 VSHT-PALRLWISAMKWDPTVCALLMDKSIFQGFLN 228 S P L W K P + L D+ F Sbjct: 178 ESQKFPRLHAWTENFKEAPIIKENLPDRDQMTAFFK 213 >5LOL-A nrPDB Length = 215 Score = 51.2 bits (121), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 37/156 (23%), Positives = 65/156 (41%), Gaps = 12/156 (7%) Query: 32 CPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQLIYESVIACE 91 CP+S R L L+ K + ++ IN+ +KP+W+ P G +PV++ + + +S + Sbjct: 22 CPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKL-DGKWVADSDVIVG 80 Query: 92 YLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECTNLKAALRQEF 151 L++ YP L + K+ + L+ + AL E Sbjct: 81 LLEEKYPEPSLKTPPEFASVGSKIFGAF-----------VTFLKSKDANDGSEKALVDEL 129 Query: 152 SNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDV 187 LE L+ + F G I+ +D L P L+V Sbjct: 130 EALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEV 165 >6JWK-A nrPDB Length = 222 Score = 49.3 bits (116), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 27/92 (29%), Positives = 47/92 (51%), Gaps = 3/92 (3%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWY---YTKHPFGHIPVLETSQC 80 +++YS S+R R+ L K + ++VV +NLR + ++P G +P L + Sbjct: 1 MQLYSFFNSSTSYRVRIALALKGLDYQVVPVNLRQGEQLRPADRQRNPMGALPTLVDADG 60 Query: 81 QLIYESVIACEYLDDAYPGRKLFPYDPYERAR 112 + +S+ +YLD P +L P DP RA+ Sbjct: 61 RRFSQSLAIIDYLDAVQPEPRLIPLDPLHRAQ 92 >1E6B-A nrPDB Length = 221 Score = 48.5 bits (114), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 46/172 (26%), Positives = 76/172 (44%), Gaps = 16/172 (9%) Query: 21 EGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEW---YYTKHPFGHIPVLET 77 E +++YS +HR R+ L K + +E + +NL ++ + +P G +P L Sbjct: 6 EEKLKLYSYWRSSCAHRVRIALALKGLDYEYIPVNLLKGDQFDSDFKKINPMGTVPALVD 65 Query: 78 SQCQLIYESVIACEYLDDAYPGRKLFPYDPYERA--RQKMLLELFCKVPHLTKECLVALR 135 +I +S YLD+ YP L P D ++RA Q M + L PH + L +R Sbjct: 66 GDV-VINDSFAIIMYLDEKYPEPPLLPRDLHKRAVNYQAMSIVLSGIQPH---QNLAVIR 121 Query: 136 CGRECTNLKA-------ALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWP 180 E N++ A+ + F+ LE++L G I + D L P Sbjct: 122 YIEEKINVEEKTAWVNNAITKGFTALEKLLVNCAGKHATGDEIYLADLFLAP 173 >3UBL-A nrPDB Length = 242 Score = 48.1 bits (113), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 31/106 (29%), Positives = 55/106 (51%), Gaps = 6/106 (5%) Query: 23 LIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQL 82 +I+++ Y ++ +L + K + +E + I ++ E + P G IPVLE + Sbjct: 3 MIKLHGASISNYVNKVKLGILEKGLEYEQIRIA-PSQEEDFLKISPMGKIPVLEMD-GKF 60 Query: 83 IYESVIACEYLDDAYPGR-KLFPYDPYERARQK---MLLELFCKVP 124 I+ES E+LD +P KL P DP+E AR + ++E + +P Sbjct: 61 IFESGAILEFLDTIFPQTPKLIPEDPWEAARVREISTIIETYLDIP 106 >3PR8-A nrPDB Length = 229 Score = 47.4 bits (111), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 49/209 (23%), Positives = 87/209 (41%), Gaps = 18/209 (8%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQLI 83 +++Y Y + +L L K + E V P+ P G +PVLET L Sbjct: 3 LKLYGFSVSNYYNMVKLALLEKGLTFEEVTFYGGQAPQALEV-SPRGKVPVLETEHGFLS 61 Query: 84 YESVIACEYLDDAYPGRKLFPYDPYERARQKMLL---ELFCKVPHLTKECLVALRCGREC 140 SVI +Y++ G+ L P DP+ +A+ + LL EL+ ++P T C G Sbjct: 62 ETSVI-LDYIEQTQGGKALLPADPFGQAKVRELLKEIELYIELPART--CYAESFFGMSV 118 Query: 141 TNL-----KAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGI----L 191 L +A L F+ L+ + + G +++ D + + + G + Sbjct: 119 EPLIKEKARADLLAGFATLKRNGRF--APYVAGEQLTLADLMFCFSVDLANAVGKKVLNI 176 Query: 192 DCVSHTPALRLWISAMKWDPTVCALLMDK 220 D ++ P + + M +P + +L DK Sbjct: 177 DFLADFPQAKALLQLMGENPHMPRILADK 205 >4MK3-A nrPDB Length = 226 Score = 47.4 bits (111), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 23/87 (26%), Positives = 43/87 (49%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQLI 83 +++Y+ + PY+ + R+VL K I +E++ N+ + +P G +P L + Sbjct: 23 MKLYASQTSPYARKVRVVLAEKKIDYEMIEENVWSPDTTIGRFNPLGKVPCLVMEDGGAV 82 Query: 84 YESVIACEYLDDAYPGRKLFPYDPYER 110 ++S + EY D P +L P ER Sbjct: 83 FDSRVIAEYADTLSPVSRLIPQGSRER 109 >4IGJ-A nrPDB Length = 242 Score = 44.7 bits (104), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 34/122 (27%), Positives = 59/122 (48%), Gaps = 7/122 (5%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEW---YYTKHPFGHIPVLETSQ- 79 +R+YS + R RL L K + +E ++L + ++ + ++P +PVLE + Sbjct: 25 LRLYSYWRSSSAWRVRLGLALKGLAYEYRAVDLLAQEQFQAAHQARNPMSQVPVLEVEED 84 Query: 80 --CQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCG 137 L+ +S+ E+L++ +P L P D + RAR + L E + LV LR Sbjct: 85 GRTHLLVQSMAILEWLEERHPEPALLPPDLWGRARVRALAEHVNSGTQPMQNALV-LRML 143 Query: 138 RE 139 RE Sbjct: 144 RE 145 >1GWC-A nrPDB Length = 230 Score = 43.9 bits (102), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 29/83 (34%), Positives = 41/83 (49%), Gaps = 4/83 (4%) Query: 32 CPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPF-GHIPVLETSQCQLIYESVIAC 90 P+ R +L L K + +E V +L K E +P IPVL + ES+I Sbjct: 15 SPFVTRVKLALALKGLSYEDVEEDLYKKSELLLKSNPVHKKIPVL-IHNGAPVCESMIIL 73 Query: 91 EYLDDAYP--GRKLFPYDPYERA 111 +Y+D+ + G L P DPYERA Sbjct: 74 QYIDEVFASTGPSLLPADPYERA 96 >5N9U-A nrPDB Length = 218 Score = 43.9 bits (102), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 38/150 (25%), Positives = 63/150 (42%), Gaps = 24/150 (16%) Query: 32 CPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQLIYESVIACE 91 CP+ R L L+ K I ++ INL +KP+W+ P G +PV++ + + +S + Sbjct: 20 CPFCQRVLLSLEEKKIPYKSHLINLGDKPQWFLEISPEGKVPVVKIDD-KWVADSDVIVG 78 Query: 92 YLDDAYP-------------GRKLFPY--------DPYERARQKMLLELFCKVPHLTKEC 130 L++ P G K+FP DP + Q +L EL HL Sbjct: 79 ILEEKNPEPPLATPPEFASVGSKIFPSFVKFLKSKDPNDGTEQALLEELKALDGHLKVHG 138 Query: 131 LVALRCGRECTNLKAALRQEFSNLEEILEY 160 G + T + +L + +LE L + Sbjct: 139 --PFIAGEKITAVDLSLAPKLYHLEVALGH 166 >3M8N-A nrPDB Length = 225 Score = 43.5 bits (101), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 52/217 (23%), Positives = 91/217 (41%), Gaps = 34/217 (15%) Query: 23 LIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINL---RNKPEWYYTKHPFGHIPVLETSQ 79 L ++YSM+ S++ RL L D + V +++ ++ + K+P G +P+LET+ Sbjct: 3 LYKLYSMQRSGNSYKVRLALALLDAPYRAVEVDILRGESRTPDFLAKNPSGQVPLLETAP 62 Query: 80 CQLIYESVIACEYLDDAYPGRKLFPYDPYERAR--QKMLLELFCKVPHLTKE----CLVA 133 + + ES YL G L P +RA Q M E P++ CLV Sbjct: 63 GRYLAESNAILWYL---AVGTSLAPDTRMDRAEALQWMFFEQHALEPNIGSAYFWLCLV- 118 Query: 134 LRCGRECTN--LKAALRQEFSNLEEILEYQNTT-FFGGTCISMIDYLLWPWFERLDVYGI 190 + GR+ L+ L + ++ L+ + + T +F +++ D L+ + D Sbjct: 119 -KGGRDLQTHALEDWLERGYAALQVMENHLKTNDYFAAGQLTIADIALYGYTHVAD---- 173 Query: 191 LDC---VSHTPALRLWIS---------AMKWDPTVCA 215 C +S PA+ W+ M W P A Sbjct: 174 -QCDFDLSTFPAVNAWLRRVEQTPGFITMDWTPETIA 209 >5NR1-A nrPDB Length = 228 Score = 42.7 bits (99), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 49/209 (23%), Positives = 82/209 (39%), Gaps = 30/209 (14%) Query: 33 PYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQ---LIYESVIA 89 P S + RL L K + + + P + + +P G PVL ++ Q +I E+ Sbjct: 14 PASRQVRLALGEKRLPFVEMQVRYWEMPPEFTSLNPSGMPPVLVETKHQRNLVICETRAI 73 Query: 90 CEYLDDAYPGRKLFPYDPYERARQKMLLELF------------------CKVPHLTKECL 131 E++++ L DP ERA + LL+ F ++ + L Sbjct: 74 LEHIEETETEPPLLGRDPAERAEARRLLQWFDRKFDNEVNGFLLHEKMEKRLLRMGAPDL 133 Query: 132 VALRCGRECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGIL 191 ALR GRE ALR +E +L Q + G +S+ D+ +D +G + Sbjct: 134 AALRQGRE------ALRMHLGYIESLL--QTRDWLAGRRMSLADFAAAAHLSVIDYFGDV 185 Query: 192 DCVSHTPALRLWISAMKWDPTVCALLMDK 220 A + W +K P +L D+ Sbjct: 186 PWKDFQ-AAKTWYMKLKSRPCFRPILADR 213 >4MDC-A nrPDB Length = 252 Score = 42.7 bits (99), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 51/214 (23%), Positives = 83/214 (38%), Gaps = 21/214 (9%) Query: 26 IYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQLIYE 85 +Y P S RL+L + E+ + T +P G +PV + + Sbjct: 26 LYHHPMSPASRFVRLILSEYGYQTELSEEQPWENRRDFLTLNPAGTLPVYVDDSMRALCG 85 Query: 86 SVIACEYLDDAYP----GRKLFPYDPYERARQKMLLELFCK------VPHLTKECLVALR 135 + I EYLD+ R+L DP++RA + L E F + L +E + L+ Sbjct: 86 ATIISEYLDETSGIMKRDRRLLAEDPFQRAEIRRLTEWFLQKMEADVTRPLVRERIFKLQ 145 Query: 136 C----GRECTNLKAALRQEFSNLEEILEY-----QNTTFFGGTCISMIDYLLWPWFERLD 186 G + K LR SN+ + ++Y + + G IS D LD Sbjct: 146 MTPDQGGGAPDSK-ILRTSRSNIRQHMKYLSWLAGSRPWLAGDRISYGDLAAAAAISVLD 204 Query: 187 VYGILDCVSHTPALRLWISAMKWDPTVCALLMDK 220 G +D S P + W +K P+ LL ++ Sbjct: 205 YLGEIDW-SDAPTAKEWYQRLKSRPSFRPLLAER 237 >3TOT-A nrPDB Length = 226 Score = 41.6 bits (96), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 22/88 (25%), Positives = 41/88 (46%) Query: 23 LIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQL 82 ++++ PY+ + R+VL K I ++ V ++ N + +P G +P L Sbjct: 2 VMKLIGSHASPYTRKVRVVLAEKKIDYQFVLEDVWNADTQIHQFNPLGKVPCLVMDDGGA 61 Query: 83 IYESVIACEYLDDAYPGRKLFPYDPYER 110 +++S + EY D P +L P ER Sbjct: 62 LFDSRVIAEYADTLSPVARLIPPSGRER 89 >3IBH-A nrPDB Length = 233 Score = 41.2 bits (95), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 60/213 (28%), Positives = 78/213 (36%), Gaps = 20/213 (9%) Query: 26 IYSMRFCPYSHRTRLVLKAKDIRHEV--VNINL----RNKPEWYYTKHPFGHIPVLETSQ 79 IY PY R R+ L K++ V V INL KPE + K+ G +PVLE Sbjct: 21 IYDTPAGPYPARVRIALAEKNMLSSVQFVRINLWKGEHKKPE-FLAKNYSGTVPVLELDD 79 Query: 80 CQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKML-----LELFCKVPHLTKECLVAL 134 LI E EY+D L P E+ M+ LEL V L Sbjct: 80 GTLIAECTAITEYIDALDGTPTLTGKTPLEKGVIHMMNKRAELELLDPVSVYFHHATPGL 139 Query: 135 RCGREC-TNLKAALRQEFSNLEEILEYQNTT-----FFGGTCISMIDYLLWPWFERLDVY 188 E N + LRQ L + Y +T + G SM D + + Sbjct: 140 GPEVELYQNKEWGLRQRDKALHG-MHYFDTVLRERPYVAGDSFSMADITVIAGLIFAAIV 198 Query: 189 GILDCVSHTPALRLWISAMKWDPTVCALLMDKS 221 L ALR W M+ P+V LL +S Sbjct: 199 K-LQVPEECEALRAWYKRMQQRPSVKKLLEIRS 230 >2JL4-A nrPDB Length = 213 Score = 39.3 bits (90), Expect = 0.001, Method: Compositional matrix adjust. Identities = 25/99 (25%), Positives = 49/99 (49%), Gaps = 4/99 (4%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNK---PEWYYTKHPFGHIPVLETSQC 80 +++Y+ SHR R+ L K + +E + ++L + + + +P +P L+T Sbjct: 2 MKLYNFWRSGTSHRLRIALNLKGVPYEYLAVHLGKEEHLKDAFKALNPQQLVPALDTG-A 60 Query: 81 QLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLEL 119 Q++ +S E+L++ YP L P D R R + L + Sbjct: 61 QVLIQSPAIIEWLEEQYPTPALLPADADGRQRVRALAAI 99 >3M3M-A nrPDB Length = 210 Score = 38.9 bits (89), Expect = 0.002, Method: Compositional matrix adjust. Identities = 45/209 (21%), Positives = 85/209 (40%), Gaps = 24/209 (11%) Query: 23 LIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINL---RNKPEWYYTKHPFGHIPVLETSQ 79 L ++Y ++ +L+L + +E +++ + E + K+P G IPVLE Sbjct: 3 LYKVYGDYRSGNCYKIKLMLNLLGLPYEWQAVDILGGDTQTEAFLAKNPNGKIPVLELED 62 Query: 80 CQLIYESVIACEYLDDAYPGRKLFPYDPYERAR--QKMLLELFCKVPHLTKECLVALRCG 137 ++ES +L D G + P +P R + Q E + P++ + L G Sbjct: 63 GTCLWESNAILNFLAD---GSQFLPSEPRLRTQVLQWQFFEQYSHEPYIAVARFIQLYEG 119 Query: 138 RECTNLKAALRQEFSNLE-------EILEYQ--NTTFFGGTCISMIDYLLWPWFERLDVY 188 L R+E+ L +++E Q T + G S+ D L+ + D Sbjct: 120 -----LPEERREEYLKLHKRGYKALDVMEKQLSRTPYLVGEHYSIADIALYAYTHVADEG 174 Query: 189 GILDCVSHTPALRLWISAMKWDPTVCALL 217 G +S P ++ W+ ++ P +L Sbjct: 175 GF--DLSRYPGIQAWMQRVQSHPRHVPML 201 >3R2Q-A nrPDB Length = 202 Score = 38.5 bits (88), Expect = 0.003, Method: Compositional matrix adjust. Identities = 22/85 (25%), Positives = 38/85 (44%) Query: 32 CPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQLIYESVIACE 91 P+ + ++L K I E +N N +P G +PVL T + + ++S I E Sbjct: 9 SPFVRKLSILLLEKGITFEFINELPYNADNGVAQFNPLGKVPVLVTEEGECWFDSPIIAE 68 Query: 92 YLDDAYPGRKLFPYDPYERARQKML 116 Y++ + P DP E R + + Sbjct: 69 YIELMNVAPAMLPRDPLESLRVRKI 93 >3NIV-A nrPDB Length = 222 Score = 38.1 bits (87), Expect = 0.004, Method: Compositional matrix adjust. Identities = 23/86 (26%), Positives = 45/86 (52%), Gaps = 6/86 (6%) Query: 36 HRTRLVLKAKDIRHEVVNINLRNK-----PEWYYTKHPFGHIPVLETSQCQLIYESVIAC 90 +R R+ L K I +E + ++L N Y+ +P +P L+ + Q++ +S+ Sbjct: 15 YRVRIALNLKKIAYEKIEVHLVNNGGEQHSLQYHQINPQELVPSLDIN-GQILSQSMAII 73 Query: 91 EYLDDAYPGRKLFPYDPYERARQKML 116 +YL++ +P L P DP+ +A K + Sbjct: 74 DYLEEIHPEMPLLPKDPFMKATLKSM 99 >1OYJ-A nrPDB Length = 231 Score = 38.1 bits (87), Expect = 0.004, Method: Compositional matrix adjust. Identities = 22/69 (31%), Positives = 35/69 (50%), Gaps = 2/69 (2%) Query: 32 CPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGH-IPVLETSQCQLIYESVIAC 90 P+ R R+ + K + E +L NK + +P IPVL + + ES++ Sbjct: 15 SPFGQRCRIAMAEKGLEFEYREEDLGNKSDLLLRSNPVHRKIPVL-LHAGRPVSESLVIL 73 Query: 91 EYLDDAYPG 99 +YLDDA+PG Sbjct: 74 QYLDDAFPG 82 >2PVQ-A nrPDB Length = 201 Score = 37.7 bits (86), Expect = 0.005, Method: Compositional matrix adjust. Identities = 32/134 (23%), Positives = 55/134 (41%), Gaps = 7/134 (5%) Query: 40 LVLKAKDIRHEVVNINLRNKPEW----YYTKHPFGHIPVLETSQCQLIYESVIACEYLDD 95 ++L + +E+ ++L+ K Y+ +P G +P LE +I ++ +Y+ D Sbjct: 16 IILSEAGLPYELEAVDLKAKKTADGGDYFAVNPRGAVPALEVKPGTVITQNAAILQYIGD 75 Query: 96 AYPGRKLFP-YDPYERARQKMLLELFCKVPHLTKECLVALRCGREC-TNLKAALRQEFSN 153 P Y ERAR + L FC H L A E + A + + Sbjct: 76 HSDVAAFKPAYGSIERARLQEALG-FCSDLHAAFSGLFAPNLSEEARAGVIANINRRLGQ 134 Query: 154 LEEILEYQNTTFFG 167 LE +L +N + G Sbjct: 135 LEAMLSDKNAYWLG 148 >3BBY-A nrPDB Length = 215 Score = 37.4 bits (85), Expect = 0.006, Method: Compositional matrix adjust. Identities = 36/160 (22%), Positives = 61/160 (38%), Gaps = 13/160 (8%) Query: 31 FCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGH---IPVLETSQCQLIYESV 87 F PY + L+ K + + I+L + T +G +P+L+ +L S Sbjct: 16 FSPYVLSAWVALQEKGLSFHIKTIDLDSGEHLQPTWQGYGQTRRVPLLQIDDFELSESSA 75 Query: 88 IACEYLDDAYP---GRKLFPYDPYERARQKMLLELF------CKVPHLTKECLVALRCGR 138 IA EYL+D + +++P D RAR + + + T + Sbjct: 76 IA-EYLEDRFAPPTWERIYPLDLENRARARQIQAWLRSDLMPIREERPTDVVFAGAKKAP 134 Query: 139 ECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLL 178 KA+ + F+ E +L FG CI+ D L Sbjct: 135 LTAEGKASAEKLFAMAEHLLVLGQPNLFGEWCIADTDLAL 174 >2GDR-A nrPDB Length = 202 Score = 36.6 bits (83), Expect = 0.009, Method: Compositional matrix adjust. Identities = 35/159 (22%), Positives = 66/159 (41%), Gaps = 10/159 (6%) Query: 27 YSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP----EWYYTKHPFGHIPVLETSQCQL 82 YS C S + L+ + E+V ++L +K + Y +P G++P L+ + Sbjct: 5 YSPGACSLS--PHIALREAGLNFELVQVDLASKKTASGQDYLEVNPAGYVPCLQLDDGRT 62 Query: 83 IYESVIACEYLDDAYPGRKLFPYD-PYERARQKMLLELFCKVPHLTKECLVALRCGRECT 141 + E +Y+ D PG++L P + +ER + L H + L E Sbjct: 63 LTEGPAIVQYVADQVPGKQLAPANGSFERYHLQQWLNFISSELHKSFSPLFNPASSDEWK 122 Query: 142 N-LKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLW 179 N ++ +L + LE+ + G +S+ D L+ Sbjct: 123 NAVRQSLNTRLGQVARQLEH--APYLLGDQLSVADIYLF 159 >4PXO-A nrPDB Length = 238 Score = 35.8 bits (81), Expect = 0.016, Method: Compositional matrix adjust. Identities = 22/91 (24%), Positives = 45/91 (49%), Gaps = 5/91 (5%) Query: 21 EGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINL----RNKPEWYYTKHPFGHIPVLE 76 + ++++Y + R R+ L K I +E V ++L ++KP+ + +P G +P L Sbjct: 21 QSMVKMYGNWRSAAAFRVRIALNLKGIAYEEVFLDLDAGDQHKPD-FLAINPQGAVPALF 79 Query: 77 TSQCQLIYESVIACEYLDDAYPGRKLFPYDP 107 + +S+ +YL++ G L P +P Sbjct: 80 DGDGPPLTQSLAILDYLEETRTGVPLLPEEP 110 >2PMT-A nrPDB Length = 203 Score = 34.7 bits (78), Expect = 0.042, Method: Compositional matrix adjust. Identities = 25/92 (27%), Positives = 38/92 (41%), Gaps = 5/92 (5%) Query: 39 RLVLKAKDIRHEVVNINLRNKP----EWYYTKHPFGHIPVLETSQCQLIYESVIACEYLD 94 +VL+ + + I+LR K + + +P G +PVL+ ++ E V +YL Sbjct: 15 HIVLRETGLDFSIERIDLRTKKTESGKDFLAINPKGQVPVLQLDNGDILTEGVAIVQYLA 74 Query: 95 DAYPGRKLF-PYDPYERARQKMLLELFCKVPH 125 D P R L P ER Q L H Sbjct: 75 DLKPDRNLIAPPKALERYHQIEWLNFLASEVH 106 >5F05-A nrPDB Length = 212 Score = 33.9 bits (76), Expect = 0.059, Method: Compositional matrix adjust. Identities = 19/80 (23%), Positives = 38/80 (47%), Gaps = 4/80 (5%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINL---RNKPEWYYTKHPFGHIPVLETSQC 80 ++++ + R L K++ E+VN+NL +K E + + +PFG +P Sbjct: 3 LKLHGSVLSTNTQRVLATLYEKEVEFELVNVNLGAGEHKQEPHISLNPFGQVPAAVDGDL 62 Query: 81 QLIYESVIACEYLDDAYPGR 100 +L +ES +Y+ Y + Sbjct: 63 KL-FESRAISQYVAHQYASK 81 >1AW9-A nrPDB Length = 216 Score = 33.9 bits (76), Expect = 0.070, Method: Compositional matrix adjust. Identities = 24/86 (27%), Positives = 39/86 (45%), Gaps = 6/86 (6%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINL---RNKPEWYYTKHPFGHIPVLETSQC 80 +++Y M P R VL K + E+V ++L +K + +PFG IP L Sbjct: 3 LKLYGMPLSPNVVRVATVLNEKGLDFEIVPVDLTTGAHKQPDFLALNPFGQIPAL-VDGD 61 Query: 81 QLIYESVIACEYLDDAYP--GRKLFP 104 ++++ES Y+ Y G L P Sbjct: 62 EVLFESRAINRYIASKYASEGTDLLP 87 >3UAR-A nrPDB Length = 227 Score = 33.9 bits (76), Expect = 0.073, Method: Compositional matrix adjust. Identities = 21/78 (26%), Positives = 37/78 (47%), Gaps = 5/78 (6%) Query: 40 LVLKAKDIRHEVVNINLRNKPEW----YYTKHPFGHIPVLETSQCQLIYESVIACEYLDD 95 +VL+ + E+ N++L K + +P G++P L+ Q++ E + +YL D Sbjct: 18 IVLREAGLDFELENVDLGTKKTGSGADFLQVNPKGYVPALQLDDGQVLTEDQVILQYLAD 77 Query: 96 AYPGRKLF-PYDPYERAR 112 P L P +ER R Sbjct: 78 LKPESGLMPPSGTFERYR 95 >1TU7-A nrPDB Length = 208 Score = 33.5 bits (75), Expect = 0.085, Method: Compositional matrix adjust. Identities = 25/75 (33%), Positives = 37/75 (49%), Gaps = 7/75 (9%) Query: 143 LKAALRQEFSNLEEILEYQNT--TFFGGTCISMIDYLLWPWFERLDVYGILD--CVSHTP 198 +K+ L E + E++L + G IS DY L FE LDV+ ILD C+ P Sbjct: 117 IKSILPGELAKFEKLLATRGNGRNLILGDKISYADYAL---FEELDVHQILDPHCLDKFP 173 Query: 199 ALRLWISAMKWDPTV 213 L+++ MK P + Sbjct: 174 LLKVFHQRMKDRPKL 188 >5D73-A nrPDB Length = 208 Score = 33.1 bits (74), Expect = 0.12, Method: Compositional matrix adjust. Identities = 23/75 (30%), Positives = 39/75 (52%), Gaps = 7/75 (9%) Query: 143 LKAALRQEFSNLEEILEYQN--TTFFGGTCISMIDYLLWPWFERLDVYGILD--CVSHTP 198 +K L E + E++L ++ F G IS +D++L FE LD++ ILD C+ P Sbjct: 117 IKDILPVELAKFEKLLATRDDGKNFILGEKISYVDFVL---FEELDIHQILDPHCLDKFP 173 Query: 199 ALRLWISAMKWDPTV 213 L+ + M+ P + Sbjct: 174 LLKAYHQRMEDRPGL 188 >5F06-A nrPDB Length = 216 Score = 32.7 bits (73), Expect = 0.16, Method: Compositional matrix adjust. Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 4/80 (5%) Query: 23 LIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINL---RNKPEWYYTKHPFGHIPVLETSQ 79 ++++Y + R L K++ E+V ++L +K + K+PFG IP LE Sbjct: 1 VLKLYGAPMSTCTSRVLTCLHEKNLDFELVPVDLFAGEHKQPPFLAKNPFGQIPALEEDD 60 Query: 80 CQLIYESVIACEYLDDAYPG 99 L +ES Y+ + + G Sbjct: 61 LTL-FESRAITSYIAEKFKG 79 >4PTS-A nrPDB Length = 348 Score = 32.3 bits (72), Expect = 0.20, Method: Compositional matrix adjust. Identities = 21/72 (29%), Positives = 37/72 (51%), Gaps = 5/72 (6%) Query: 18 PVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINL----RNKPEWYYTKHPFGHIP 73 PV G R+ + R CP+++RT +V + + + V+++ L +K W + P G P Sbjct: 42 PVEPGRYRLIAARACPWANRTLIVRRLLGLEN-VLSLGLCGPTHDKNSWTFDLDPGGVDP 100 Query: 74 VLETSQCQLIYE 85 VL + + YE Sbjct: 101 VLGIPRLKDAYE 112 >5F07-A nrPDB Length = 213 Score = 30.8 bits (68), Expect = 0.56, Method: Compositional matrix adjust. Identities = 23/84 (27%), Positives = 41/84 (48%), Gaps = 10/84 (11%) Query: 23 LIRIY--SMRFCPYSHRTRLVLKAKDIRHEVVNINL----RNKPEWYYTKHPFGHIPVLE 76 ++++Y ++ CP R L K + ++V+++L + PE + K PFG +PV+E Sbjct: 1 VVKVYGPAVAVCP--QRVMACLLEKGVEFDLVHVDLDSGEQKLPE-FLLKQPFGQVPVVE 57 Query: 77 TSQCQLIYESVIACEYLDDAYPGR 100 +L +ES Y Y R Sbjct: 58 DGDFKL-FESRAIIRYYAAKYEDR 80 >3GRX-A nrPDB Length = 82 Score = 30.8 bits (68), Expect = 0.60, Method: Compositional matrix adjust. Identities = 11/32 (34%), Positives = 20/32 (62%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNIN 55 + IY+ CPYSHR + +L +K + + + I+ Sbjct: 3 VEIYTKETCPYSHRAKALLSSKGVSFQELPID 34 >3M1G-A nrPDB Length = 362 Score = 29.3 bits (64), Expect = 1.6, Method: Compositional matrix adjust. Identities = 19/71 (26%), Positives = 34/71 (47%), Gaps = 5/71 (7%) Query: 18 PVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINL----RNKPEWYYTKHPFGHIP 73 PV G R+ + R CP++HRT + + + + V+++ L + W + P P Sbjct: 56 PVEAGRYRLVAARACPWAHRTVITRRLLGLEN-VISLGLTGPTHDVRSWTFDLDPNHLDP 114 Query: 74 VLETSQCQLIY 84 VL+ + Q Y Sbjct: 115 VLQIPRLQDAY 125 >2D2Z-A nrPDB Length = 261 Score = 28.5 bits (62), Expect = 2.5, Method: Compositional matrix adjust. Identities = 37/164 (22%), Positives = 62/164 (37%), Gaps = 12/164 (7%) Query: 28 SMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQLIYESV 87 S+ CP+S R ++L K + V ++L+ KP P H P + T ++ + Sbjct: 31 SIGNCPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAPGTHPPFI-TFNSEVKTDVN 89 Query: 88 IACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTK----ECLVALRCGRECT-- 141 E+L++ K P +++F K K E AL G T Sbjct: 90 KIEEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTLQ 149 Query: 142 ----NLKAALRQEFS-NLEEILEYQNTTFFGGTCISMIDYLLWP 180 L + L E N E +++ F G +++ D L P Sbjct: 150 KLDEYLNSPLPDEIDENSMEDIKFSTRKFLDGNEMTLADCNLLP 193 >1N2A-A nrPDB Length = 201 Score = 28.5 bits (62), Expect = 3.0, Method: Compositional matrix adjust. Identities = 14/41 (34%), Positives = 21/41 (51%) Query: 63 YYTKHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLF 103 Y+ +P G +P L L+ E V +YL D+ P R+L Sbjct: 43 YFAVNPKGQVPALLLDDGTLLTEGVAIMQYLADSVPDRQLL 83 >5W0C-A nrPDB Length = 477 Score = 28.1 bits (61), Expect = 3.3, Method: Compositional matrix adjust. Identities = 27/104 (25%), Positives = 44/104 (42%), Gaps = 20/104 (19%) Query: 10 GKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPF 69 G+G PPGP P +I L + KDI + N++ P + F Sbjct: 8 GRGKLPPGPTPLPVI------------GNILQIGIKDISKSLTNLSKVYGPVFTLY---F 52 Query: 70 GHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQ 113 G P++ + + E++I L + + GR +FP ERA + Sbjct: 53 GLKPIVVLHGYEAVKEALID---LGEEFSGRGIFPL--AERANR 91 >3C8E-A nrPDB Length = 288 Score = 28.1 bits (61), Expect = 3.7, Method: Compositional matrix adjust. Identities = 13/47 (27%), Positives = 22/47 (46%), Gaps = 2/47 (4%) Query: 150 EFSNLEEILEYQ--NTTFFGGTCISMIDYLLWPWFERLDVYGILDCV 194 E L ++L+ Q F G ++ D +WPWF + + G+ D Sbjct: 182 EAKRLLDVLDKQLAQHKFVAGDEYTIADMAIWPWFGNVVLGGVYDAA 228 >1AXD-A nrPDB Length = 209 Score = 27.3 bits (59), Expect = 6.6, Method: Compositional matrix adjust. Identities = 17/59 (28%), Positives = 28/59 (47%), Gaps = 4/59 (6%) Query: 37 RTRLVLKAKDIRHEVVNINL---RNKPEWYYTKHPFGHIPVLETSQCQLIYESVIACEY 92 R L+ +E+V IN +K + ++PFG +P L+ L +ES C+Y Sbjct: 16 RCATALEEAGSDYEIVPINFATAEHKSPEHLVRNPFGQVPALQDGDLYL-FESRAICKY 73 >4TR1-A nrPDB Length = 92 Score = 27.3 bits (59), Expect = 6.7, Method: Compositional matrix adjust. Identities = 11/37 (29%), Positives = 21/37 (56%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP 60 I IY+ +CPYS + +L +K + + V++ +K Sbjct: 4 ITIYTKNYCPYSKKAVSLLSSKGVDFKEVDVTHDSKA 40 >3J6B-7 nrPDB Length = 146 Score = 26.9 bits (58), Expect = 8.4, Method: Compositional matrix adjust. Identities = 21/80 (26%), Positives = 36/80 (45%), Gaps = 9/80 (11%) Query: 1 MSGDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTR-----LVLKAKDIR-HEVVNI 54 +S TR G+G PGP IY C ++ + + K +D++ HE++ Sbjct: 2 ISSCVTRCFGRGKCLPGPATAS---IYQTIRCISTNSNKAAEAPIFPKLEDVKMHELIGN 58 Query: 55 NLRNKPEWYYTKHPFGHIPV 74 N K +Y + G++PV Sbjct: 59 NNFGKKTYYVERSRTGNLPV 78 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3QAG-A nrPDB 342 9e-95 3LFL-A nrPDB 303 6e-83 3WD6-A nrPDB 213 4e-56 2VO4-A nrPDB 210 4e-55 4CHS-A nrPDB 209 6e-55 5J5N-A nrPDB 206 9e-54 5ECL-B nrPDB 203 5e-53 4J2F-A nrPDB 202 1e-52 5G5A-A nrPDB 200 4e-52 3RBT-A nrPDB 198 2e-51 6EP7-A nrPDB 192 1e-49 4QQ7-A nrPDB 181 3e-46 2CZ2-A nrPDB 179 1e-45 1FW1-A nrPDB 178 2e-45 4MDC-A nrPDB 175 1e-44 5ELG-A nrPDB 170 5e-43 5D9W-A nrPDB 167 3e-42 4PQI-A nrPDB 167 5e-42 5LOL-A nrPDB 166 7e-42 3IBH-A nrPDB 166 7e-42 5NR1-A nrPDB 165 2e-41 5IQY-A nrPDB 164 4e-41 1E6B-A nrPDB 161 4e-40 3PR8-A nrPDB 160 4e-40 4AGS-A nrPDB 160 4e-40 5N9U-A nrPDB 149 9e-37 3TOT-A nrPDB 148 2e-36 3M8N-A nrPDB 147 5e-36 4MK3-A nrPDB 146 8e-36 1GWC-A nrPDB 146 9e-36 4IGJ-A nrPDB 144 4e-35 3UBL-A nrPDB 127 6e-30 2JL4-A nrPDB 124 5e-29 6JWK-A nrPDB 120 5e-28 Sequences not found previously or not previously below threshold: 1OYJ-A nrPDB 130 6e-31 3NIV-A nrPDB 124 3e-29 3LG6-A nrPDB 124 4e-29 4PXO-A nrPDB 120 5e-28 3M3M-A nrPDB 118 3e-27 3VWX-A nrPDB 110 5e-25 4PNG-A nrPDB 110 7e-25 4YH2-A nrPDB 109 9e-25 1AW9-A nrPDB 108 2e-24 3R2Q-A nrPDB 108 2e-24 5F06-A nrPDB 107 5e-24 3UAR-A nrPDB 97 6e-21 5F07-A nrPDB 96 1e-20 5A5K-A nrPDB 94 7e-20 4RI7-A nrPDB 92 2e-19 2GDR-A nrPDB 92 2e-19 3C8E-A nrPDB 91 3e-19 5EY6-A nrPDB 89 1e-18 2IL3-A nrPDB 89 2e-18 4IKH-A nrPDB 88 3e-18 1AXD-A nrPDB 88 3e-18 6F05-A nrPDB 86 1e-17 1JLV-A nrPDB 86 1e-17 1F2E-A nrPDB 86 2e-17 2PMT-A nrPDB 84 5e-17 3LSZ-A nrPDB 84 6e-17 3GX0-A nrPDB 84 6e-17 5F05-A nrPDB 81 4e-16 2PVQ-A nrPDB 80 8e-16 1G6W-A nrPDB 79 1e-15 1PN9-A nrPDB 79 3e-15 1V2A-A nrPDB 78 3e-15 1YQ1-A nrPDB 76 1e-14 5ZWP-A nrPDB 76 2e-14 5F0G-A nrPDB 76 2e-14 4MPF-A nrPDB 76 2e-14 5Y7I-A nrPDB 76 2e-14 3MAK-A nrPDB 73 9e-14 5D73-A nrPDB 72 2e-13 1VF1-A nrPDB 70 8e-13 3GH6-A nrPDB 70 1e-12 4Q5F-A nrPDB 69 1e-12 5F8B-A nrPDB 69 1e-12 2VCV-A nrPDB 69 2e-12 1N2A-A nrPDB 69 2e-12 3I6A-A nrPDB 68 4e-12 1F3B-A nrPDB 67 6e-12 2VCT-A nrPDB 67 6e-12 2D2Z-A nrPDB 67 6e-12 1PL2-A nrPDB 67 6e-12 2C3Q-A nrPDB 66 1e-11 2R5G-A nrPDB 65 2e-11 3FY7-A nrPDB 65 3e-11 1GUL-A nrPDB 65 3e-11 5LCZ-A nrPDB 65 3e-11 3BBY-A nrPDB 65 3e-11 1TU7-A nrPDB 64 4e-11 4Q5R-A nrPDB 64 7e-11 1B48-A nrPDB 64 7e-11 4K0G-A nrPDB 61 3e-10 1EV4-A nrPDB 61 4e-10 1G7O-A nrPDB 60 7e-10 2AAW-A nrPDB 59 1e-09 1ZL9-A nrPDB 59 2e-09 4FQU-A nrPDB 57 5e-09 2FHE-A nrPDB 57 6e-09 3IR4-A nrPDB 57 6e-09 3PPU-A nrPDB 55 2e-08 2WRT-A nrPDB 55 3e-08 4LMW-A nrPDB 54 4e-08 3KXO-A nrPDB 54 4e-08 1U3I-A nrPDB 53 1e-07 6GZF-A nrPDB 53 1e-07 6GCB-A nrPDB 52 2e-07 2DC5-A nrPDB 52 2e-07 1HNA-A nrPDB 52 3e-07 2GLR-A nrPDB 52 3e-07 2CA8-A nrPDB 52 3e-07 1GSQ-A nrPDB 51 4e-07 5Y9Z-A nrPDB 51 4e-07 4GTU-A nrPDB 51 4e-07 2YV7-A nrPDB 51 4e-07 1FHE-A nrPDB 50 9e-07 6GC9-A nrPDB 50 9e-07 4LMV-A nrPDB 50 1e-06 18GS-A nrPDB 50 1e-06 2PBJ-A nrPDB 48 3e-06 4PTS-A nrPDB 48 4e-06 3M1G-A nrPDB 47 8e-06 1M0U-A nrPDB 47 8e-06 1DUG-A nrPDB 47 8e-06 4Q5Q-A nrPDB 47 9e-06 1BG5-A nrPDB 47 1e-05 1B8X-A nrPDB 47 1e-05 4BVY-B nrPDB 46 1e-05 1XWK-A nrPDB 46 1e-05 5FWG-A nrPDB 46 2e-05 3GTU-B nrPDB 45 2e-05 1B4P-A nrPDB 45 3e-05 4G0L-A nrPDB 45 3e-05 2WDU-A nrPDB 44 5e-05 5AN1-A nrPDB 43 2e-04 3GRX-A nrPDB 40 7e-04 2X8H-A nrPDB 39 0.002 4USS-A nrPDB 39 0.002 1GSU-A nrPDB 38 0.003 5LKB-A nrPDB 37 0.005 4LA1-A nrPDB 36 0.012 2KLX-A nrPDB 36 0.015 3QMX-A nrPDB 36 0.017 5CAX-A nrPDB 35 0.026 1Z7R-A nrPDB 32 0.18 4TR1-A nrPDB 32 0.20 5FQ8-B nrPDB 32 0.22 1EP3-A nrPDB 32 0.23 5JBE-A nrPDB 32 0.34 6GFF-A nrPDB 31 0.42 3RJR-A nrPDB 31 0.42 5FFO-C nrPDB 31 0.43 4YUB-A nrPDB 31 0.45 3IC4-A nrPDB 31 0.52 1HX8-A nrPDB 31 0.59 5UE9-A nrPDB 31 0.59 2MZC-A nrPDB 30 1.3 2WX2-A nrPDB 30 1.3 3LGC-A nrPDB 30 1.3 6AZI-A nrPDB 29 1.7 1NM3-A nrPDB 29 1.9 3UIW-A nrPDB 29 1.9 1QYC-A nrPDB 29 2.1 6MUQ-A nrPDB 29 2.7 3E6I-A nrPDB 27 7.2 >3QAG-A nrPDB Length = 239 Score = 342 bits (877), Expect = 9e-95, Method: Composition-based stats. Identities = 233/239 (97%), Positives = 233/239 (97%) Query: 1 MSGDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP 60 MSGDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP Sbjct: 1 MSGDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP 60 Query: 61 EWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELF 120 EWYYTKHPFGHIPVLETSQ QLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELF Sbjct: 61 EWYYTKHPFGHIPVLETSQSQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELF 120 Query: 121 CKVPHLTKECLVALRCGRECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWP 180 KVPHLTKECLVALR GRE TNLKAALRQEFSNLEEILEYQNTTFFGGT ISMIDYLLWP Sbjct: 121 SKVPHLTKECLVALRSGRESTNLKAALRQEFSNLEEILEYQNTTFFGGTSISMIDYLLWP 180 Query: 181 WFERLDVYGILDCVSHTPALRLWISAMKWDPTVCALLMDKSIFQGFLNLYFQNNPNAFD 239 WFERLDVYGILDCVSHTPALRLWISAMKWDPTV ALLMDKSIFQGFLNLYFQNNPNAFD Sbjct: 181 WFERLDVYGILDCVSHTPALRLWISAMKWDPTVSALLMDKSIFQGFLNLYFQNNPNAFD 239 >3LFL-A nrPDB Length = 240 Score = 303 bits (775), Expect = 6e-83, Method: Composition-based stats. Identities = 154/242 (63%), Positives = 187/242 (77%), Gaps = 2/242 (0%) Query: 1 MSGDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP 60 MSG++ R+LGKGS PPGPVPEG IRIYSMRFCP++ RTRLVLKAK IRHEV+NINL+NKP Sbjct: 1 MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKP 60 Query: 61 EWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELF 120 EW++ K+PFG +PVLE SQ QLIYES I CEYLD+AYPG+KL P DPYE+A QKM+LELF Sbjct: 61 EWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELF 120 Query: 121 CKVPHLTKECLVALRCGRECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWP 180 KVP L + + + LK R+EF+ LE +L + TTFFGG ISMIDYL+WP Sbjct: 121 SKVPSLVGS-FIRSQNKEDYAGLKEEFRKEFTKLE-VLTNKKTTFFGGNSISMIDYLIWP 178 Query: 181 WFERLDVYGILDCVSHTPALRLWISAMKWDPTVCALLMDKSIFQGFLNLYFQNNPNAFDF 240 WFERL+ + +CV HTP L+LW++AMK DPTV ALL + +QGFL LY QN+P A D+ Sbjct: 179 WFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDY 238 Query: 241 GL 242 GL Sbjct: 239 GL 240 >3WD6-A nrPDB Length = 256 Score = 213 bits (543), Expect = 4e-56, Method: Composition-based stats. Identities = 85/238 (35%), Positives = 125/238 (52%), Gaps = 13/238 (5%) Query: 6 TRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYT 65 T+ L KG P P G +R+Y+MR+CPY+ RT L L AK I +EVVNI+L +KPEW T Sbjct: 14 TKHLRKGD--PLPPFNGKLRVYNMRYCPYAQRTILALNAKQIDYEVVNIDLIDKPEWLTT 71 Query: 66 KHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPH 125 K F +P +E ++ IYES++ EYLD+ YP R L P DP ++A K+++E + Sbjct: 72 KSAFAKVPAIEIAEDVTIYESLVTVEYLDEVYPKRPLLPQDPLKKALDKIIVEASAPIQS 131 Query: 126 LTKECLVALRCGRECTNLK--AALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFE 183 L + + + N + AA + ++E L+ + T F G+ DY++WPWFE Sbjct: 132 L----FIKILKFSDTVNEEHVAAYHKALDFIQEQLKNRGTVFLDGSEPGYADYMIWPWFE 187 Query: 184 RLDVYGILDCVSHTPA----LRLWISAMKWDPTVCALLMDKSIFQGFLNLYFQNN-PN 236 RL + + V P+ L +I M D V L+ I F Y + PN Sbjct: 188 RLRAFAHDERVRLEPSKYSLLLEYIDNMLKDSAVSQYLIPLEILAKFHEAYTKKERPN 245 >2VO4-A nrPDB Length = 219 Score = 210 bits (534), Expect = 4e-55, Method: Composition-based stats. Identities = 56/218 (25%), Positives = 90/218 (41%), Gaps = 9/218 (4%) Query: 21 EGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPF-GHIPVLETSQ 79 + + + P+ R R+ L K I++E +LRNK +P IPVL Sbjct: 2 QDEVVLLDFWPSPFGMRVRIALAEKGIKYEYKEEDLRNKSPLLLQMNPVHKKIPVL-IHN 60 Query: 80 CQLIYESVIACEYLDDAYPGR-KLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGR 138 + I ES+IA +Y+++ + R L P DPY+RA+ + + K + G Sbjct: 61 GKPICESLIAVQYIEEVWNDRNPLLPSDPYQRAQTRFWADYVDKKI-YDLGRKIWTSKGE 119 Query: 139 ECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWP---WFERLDVYGILDCVS 195 E K + LEE L + T+FGG + +D L P WF+ + +G L+ S Sbjct: 120 EKEAAKKEFIEALKLLEEQL--GDKTYFGGDNLGFVDIALVPFYTWFKAYETFGTLNIES 177 Query: 196 HTPALRLWISAMKWDPTVCALLMDKSIFQGFLNLYFQN 233 P W +V L D+ F+ + Sbjct: 178 ECPKFIAWAKRCLQKESVAKSLPDQQKVYEFIMDLRKK 215 >4CHS-A nrPDB Length = 219 Score = 209 bits (533), Expect = 6e-55, Method: Composition-based stats. Identities = 56/218 (25%), Positives = 90/218 (41%), Gaps = 9/218 (4%) Query: 21 EGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPF-GHIPVLETSQ 79 + + P+ R R+ L K I +E +LRNK +P IPVL Sbjct: 2 TDEVVLLDFWPSPFGMRVRIALAEKGIEYEYKEEDLRNKSPLLLQMNPVHKKIPVL-IHN 60 Query: 80 CQLIYESVIACEYLDDAYPGR-KLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGR 138 + I ES+IA +Y+++ + R L P DPY+RA+ + + H + + + G Sbjct: 61 GKPISESLIAVQYIEEVWNDRNPLLPSDPYQRAQARFWADYVDIKIHDLGKKIWTSK-GE 119 Query: 139 ECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWP---WFERLDVYGILDCVS 195 E K + LEE L + T+FGG I +D L P WF+ + +G L+ + Sbjct: 120 EKEAAKKEFIEALKLLEEQL--GDKTYFGGDNIGFVDIALVPFYTWFKVYETFGSLNIEN 177 Query: 196 HTPALRLWISAMKWDPTVCALLMDKSIFQGFLNLYFQN 233 P W +V L D+ F+ + Sbjct: 178 ECPRFVAWAKRCLQKESVAKSLPDQHKVYEFVVEIRKK 215 >5J5N-A nrPDB Length = 231 Score = 206 bits (523), Expect = 9e-54, Method: Composition-based stats. Identities = 49/213 (23%), Positives = 81/213 (38%), Gaps = 9/213 (4%) Query: 26 IYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGH-IPVLETSQCQLIY 84 + P+ R RL L K +++E +L NK +P IPVL + + Sbjct: 19 LLDFWPSPFGMRVRLALAEKGVKYEYSEEDLWNKSALLLQMNPVNKQIPVLV-HNGKPVC 77 Query: 85 ESVIACEYLDDAYPGR-KLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECTNL 143 ES+I +Y+D+ + L P DPY+RA+ + + K + + G E Sbjct: 78 ESLIIVQYIDEVWKDSAPLLPSDPYQRAQSRFWADFVDKKI-YDLGRKIWTKKGEEQEAA 136 Query: 144 KAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWP---WFERLDVYGILDCVSHTPAL 200 K +E L + +FGG I +D L P WF + G + + P + Sbjct: 137 KKDFIDSLKLMEGEL--GDKPYFGGETIGYVDIALVPFYSWFYAYETIGNFNIEAECPKM 194 Query: 201 RLWISAMKWDPTVCALLMDKSIFQGFLNLYFQN 233 + TV L D F+ + + Sbjct: 195 IAYCKRCLQKETVSKALEDPQKVYDFVLMLMKK 227 >5ECL-B nrPDB Length = 223 Score = 203 bits (517), Expect = 5e-53, Method: Composition-based stats. Identities = 53/216 (24%), Positives = 88/216 (40%), Gaps = 13/216 (6%) Query: 26 IYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPF-GHIPVLETSQCQLIY 84 + + R R+ L+ K + E + NK +P IPVL + + Sbjct: 13 LLDYWPSMFGMRARVALREKGVEFEYREEDFSNKSPLLLQSNPIHKKIPVLV-HNGKPVC 71 Query: 85 ESVIACEYLDDAYPGR-KLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECTNL 143 ES+ +Y+D+A+P + FP DPY RA+ + + F + V + G E Sbjct: 72 ESLNVVQYVDEAWPEKNPFFPSDPYGRAQARFWAD-FVDKKFTDAQFKVWGKKGEE---- 126 Query: 144 KAALRQEFSNLEEILEYQ--NTTFFGGTCISMIDYLLW---PWFERLDVYGILDCVSHTP 198 + A ++EF +ILE + + +FGG +D L WF+ + +G S +P Sbjct: 127 QEAGKKEFIEAVKILESELGDKPYFGGDSFGYVDISLITFSSWFQAYEKFGNFSIESESP 186 Query: 199 ALRLWISAMKWDPTVCALLMDKSIFQGFLNLYFQNN 234 L W +V L D + Y +NN Sbjct: 187 KLIAWAKRCMEKESVSKSLPDSEKIVAYAAEYRKNN 222 >4J2F-A nrPDB Length = 223 Score = 202 bits (514), Expect = 1e-52, Method: Composition-based stats. Identities = 53/221 (23%), Positives = 88/221 (39%), Gaps = 16/221 (7%) Query: 22 GLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPF-GHIPVLETSQC 80 +++++ P+S R LK K I +E V +L NK +P IPVL Sbjct: 3 EVLKLHGAWPSPFSCRVIWALKLKGIPYEYVEEDLFNKSPLLLQYNPVHKKIPVLV-HGG 61 Query: 81 QLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGREC 140 + I ES I EYLD+ +P L P DP+ERA + ++ K + + Sbjct: 62 KPICESTIILEYLDETWPENPLLPSDPHERAVARFWVKFIED-----KGTAIWNIFRTKG 116 Query: 141 TNLKAALRQEFSNLEEILEY----QNTTFFGGTCISMIDYL---LWPWFERLDVYGILDC 193 L+ A++ L+ I E+ + +FGG I ++D + W ++ + Sbjct: 117 EELEKAVKNCLEVLKTIEEHAMGVSDDKYFGGDKIGIVDIAFCGIAHWLGVIEEVAGVKV 176 Query: 194 VSH--TPALRLWISAMKWDPTVCALLMDKSIFQGFLNLYFQ 232 + P L W K P + L D+ F + Sbjct: 177 LESQKFPRLHAWTENFKEAPIIKENLPDRDQMTAFFKRRRE 217 >5G5A-A nrPDB Length = 221 Score = 200 bits (509), Expect = 4e-52, Method: Composition-based stats. Identities = 51/215 (23%), Positives = 89/215 (41%), Gaps = 13/215 (6%) Query: 26 IYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPF-GHIPVLETSQCQLIY 84 + + RTR+ L+ K+++ + +L NK +P IPVL + Sbjct: 7 LLDFWPSMFGMRTRIALEEKNVKFDYREQDLWNKSPILLEMNPVHKKIPVL-IHNGNPVC 65 Query: 85 ESVIACEYLDDAYPGR-KLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECTNL 143 ES+I EY+D+ +P + L P DPY+RA+ K + K + + + + Sbjct: 66 ESLIQIEYIDEVWPSKTPLLPSDPYQRAQAKFWGDFIDKKVYASARLIWGAKGEE----- 120 Query: 144 KAALRQEFSNLEEILEYQ--NTTFFGGTCISMIDYLL---WPWFERLDVYGILDCVSHTP 198 A ++EF + + LE + + T+FGG +D L + WFE + +G + P Sbjct: 121 HEAGKKEFIEILKTLESELGDKTYFGGETFGYVDIALIGFYSWFEAYEKFGSFSIEAECP 180 Query: 199 ALRLWISAMKWDPTVCALLMDKSIFQGFLNLYFQN 233 L W +V L D F+ + Sbjct: 181 KLIAWGKRCVERESVAKSLPDSEKIIKFVPELRKK 215 >3RBT-A nrPDB Length = 246 Score = 198 bits (503), Expect = 2e-51, Method: Composition-based stats. Identities = 72/236 (30%), Positives = 111/236 (47%), Gaps = 17/236 (7%) Query: 3 GDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEW 62 G ++ G PP P +R+Y + PY HR LVL+AK I++EV ++ PEW Sbjct: 7 GTYFHSVNAGVIPP-PALTDKLRLYHVDMNPYGHRVLLVLEAKRIKYEVYRLDPLRLPEW 65 Query: 63 YYTKHPFGHIPVLETSQCQ---LIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLEL 119 + K+P IPVLE Q ++ESV+ C+YLD+ Y L +DPY +A+ ++L+E Sbjct: 66 FRAKNPRLKIPVLEIPTDQGDRFLFESVVICDYLDEKYTRHTLHSHDPYVKAQDRLLIER 125 Query: 120 FCKVPHLTKECL-VALRCGRECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLL 178 F ++ + EC G E + Q E+ L + T +FGG M+DY++ Sbjct: 126 FNELIKGSLECFDTNFAFGSE------QIIQTLEIFEKELTNRGTNYFGGNRPGMLDYMV 179 Query: 179 WPWFERL------DVYGILDCVSHTPALRLWISAMKWDPTVCALLMDKSIFQGFLN 228 WPW ERL + ++ S P W M+ D V + + Sbjct: 180 WPWVERLYLLRCVNDRKFVEKKSLFPNFADWGDQMQLDDIVKKHAHSPQEYFDYYK 235 >6EP7-A nrPDB Length = 220 Score = 192 bits (487), Expect = 1e-49, Method: Composition-based stats. Identities = 51/219 (23%), Positives = 92/219 (42%), Gaps = 13/219 (5%) Query: 21 EGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPF-GHIPVLETSQ 79 E I + Y RTR+ L+ K +++E +L NK +P IPVL + Sbjct: 2 EEEIILLDYWASMYGMRTRIALEEKKVKYEYREEDLSNKSPLLLQMNPIHKKIPVL-IHE 60 Query: 80 CQLIYESVIACEYLDDAYPGR-KLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGR 138 + I ES+I +Y+D+ +P + P DPY+RA+ + + K ++ + L + Sbjct: 61 GKPICESIIQVQYIDELWPDTNPILPSDPYQRAQARFWADYIDKKTYVPCKALWS----- 115 Query: 139 ECTNLKAALRQEFSNLEEILEYQ--NTTFFGGTCISMIDYL---LWPWFERLDVYGILDC 193 E + A + EF + + L+ + + +FGG ++D + WF + L Sbjct: 116 ESGEKQEAAKIEFIEVLKTLDSELGDKYYFGGNEFGLVDIAFIGFYSWFRTYEEVANLSI 175 Query: 194 VSHTPALRLWISAMKWDPTVCALLMDKSIFQGFLNLYFQ 232 V P L W +V L D ++ + + Sbjct: 176 VLEFPKLMAWAQRCLKRESVAKALPDSDKVLKSVSDHRK 214 >4QQ7-A nrPDB Length = 207 Score = 181 bits (459), Expect = 3e-46, Method: Composition-based stats. Identities = 65/209 (31%), Positives = 99/209 (47%), Gaps = 11/209 (5%) Query: 20 PEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQ 79 P ++ +YS CP+S R RLVL K + E+ +++L NKPE +P+G +P+L + Sbjct: 2 PGSMMVLYSGTTCPFSQRCRLVLFEKGMDFEIRDVDLFNKPEDISVMNPYGQVPILV-ER 60 Query: 80 CQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLL-----ELFCKVPHLTKECLVAL 134 ++YES I EY+D+ +P +L P DP +RAR ++ L ELF V L E A Sbjct: 61 DLILYESNIINEYIDERFPHPQLMPADPVQRARARLFLLNFEKELFVHVSTLENEKGKAA 120 Query: 135 RCGRECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCV 194 E L A+R + L I + + G SM+D + P RLD YGI Sbjct: 121 EKNHEKARL--AIRDRLTQLAPI--FVKNKYMLGEEFSMLDVAIAPLLWRLDHYGIELSK 176 Query: 195 SHTPALRLWISAMKWDPTVCALLMDKSIF 223 + P ++ + + P L Sbjct: 177 NAAPLMK-YAERIFSRPAYIEALTPSEKV 204 >2CZ2-A nrPDB Length = 223 Score = 179 bits (453), Expect = 1e-45, Method: Composition-based stats. Identities = 47/176 (26%), Positives = 78/176 (44%), Gaps = 8/176 (4%) Query: 22 GLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINL-----RNKPEWYYTKHPFGHIPVLE 76 G +YS S R R+ L K I +E+V INL + E + T +P +P L+ Sbjct: 11 GKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALK 70 Query: 77 TSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRC 136 I +S+ EYL++ P +L P DP +RA +M+ +L + V + Sbjct: 71 I-DGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMISDLIASGIQPLQNLSVLKQV 129 Query: 137 GREC--TNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGI 190 G+E + + F+ LE+IL+ + G +SM D L P + + + Sbjct: 130 GQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVANAERFKV 185 >1FW1-A nrPDB Length = 216 Score = 178 bits (452), Expect = 2e-45, Method: Composition-based stats. Identities = 45/176 (25%), Positives = 78/176 (44%), Gaps = 8/176 (4%) Query: 22 GLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINL-----RNKPEWYYTKHPFGHIPVLE 76 G +YS S R R+ L K I ++ V INL + + + +P +P L+ Sbjct: 4 GKPILYSYFRSSCSWRVRIALALKGIDYKTVPINLIKDGGQQFSKDFQALNPMKQVPTLK 63 Query: 77 TSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRC 136 I++S+ EYL++ P +L P DP +RA +M+ +L + V + Sbjct: 64 I-DGITIHQSLAIIEYLEETRPTPRLLPQDPKKRASVRMISDLIAGGIQPLQNLSVLKQV 122 Query: 137 GRE--CTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGI 190 G E T + A+ F+ LE+IL+ + G ++M D L P + + + Sbjct: 123 GEEMQLTWAQNAITCGFNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAERFKV 178 >4MDC-A nrPDB Length = 252 Score = 175 bits (444), Expect = 1e-44, Method: Composition-based stats. Identities = 49/219 (22%), Positives = 83/219 (37%), Gaps = 19/219 (8%) Query: 20 PEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQ 79 + + +Y P S RL+L + E+ + T +P G +PV Sbjct: 20 FQSMPTLYHHPMSPASRFVRLILSEYGYQTELSEEQPWENRRDFLTLNPAGTLPVYVDDS 79 Query: 80 CQLIYESVIACEYLDDAYP----GRKLFPYDPYERARQKMLLELFCK------VPHLTKE 129 + + + I EYLD+ R+L DP++RA + L E F + L +E Sbjct: 80 MRALCGATIISEYLDETSGIMKRDRRLLAEDPFQRAEIRRLTEWFLQKMEADVTRPLVRE 139 Query: 130 CLVALRCGRE---CTNLKAALRQEFSNLEEILEY-----QNTTFFGGTCISMIDYLLWPW 181 + L+ + LR SN+ + ++Y + + G IS D Sbjct: 140 RIFKLQMTPDQGGGAPDSKILRTSRSNIRQHMKYLSWLAGSRPWLAGDRISYGDLAAAAA 199 Query: 182 FERLDVYGILDCVSHTPALRLWISAMKWDPTVCALLMDK 220 LD G +D S P + W +K P+ LL ++ Sbjct: 200 ISVLDYLGEIDW-SDAPTAKEWYQRLKSRPSFRPLLAER 237 >5ELG-A nrPDB Length = 221 Score = 170 bits (430), Expect = 5e-43, Method: Composition-based stats. Identities = 41/194 (21%), Positives = 74/194 (38%), Gaps = 16/194 (8%) Query: 32 CPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQLIYESVIACE 91 CP+S R L L+ K + +++ INL +KP+W+ P G +PVL+ + + +S + Sbjct: 20 CPFSQRALLTLEEKSLTYKIHLINLSDKPQWFLDISPQGKVPVLKIDD-KWVTDSDVIVG 78 Query: 92 YLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECTNLKAALRQEF 151 L++ YP L K E ++ L+ + AL E Sbjct: 79 ILEEKYPDPPL-----------KTPAEFASVGSNIFGTFGTFLKSKDSNDGSEHALLVEL 127 Query: 152 SNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDV----YGILDCVSHTPALRLWISAM 207 LE L+ + F G +S +D L P L V + P + ++ + Sbjct: 128 EALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKSWSVPESFPHVHNYMKTL 187 Query: 208 KWDPTVCALLMDKS 221 + ++ Sbjct: 188 FSLDSFEKTKTEEK 201 >5D9W-A nrPDB Length = 230 Score = 167 bits (423), Expect = 3e-42, Method: Composition-based stats. Identities = 41/198 (20%), Positives = 69/198 (34%), Gaps = 16/198 (8%) Query: 32 CPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQLIYESVIACE 91 P+S R L L+ K + +E+ I+++NKP+W+ P G +PV + I +S + + Sbjct: 37 SPFSQRVLLTLEEKKVPYEMKLIDVQNKPDWFLKISPEGKVPVFNGGDGKWIPDSDVITQ 96 Query: 92 YLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECTNLKAALRQEF 151 +++ YP L Y K+ L+ + AL E Sbjct: 97 VIEEKYPTPSLVTPPEYASVGSKIFSCF-----------TTFLKSKDPNDGSEKALLTEL 145 Query: 152 SNLEEILEYQNTTFFGGTCISMIDYLLWPWFER----LDVYGILDCVSHTPALRLWISAM 207 LEE L+ F G IS D L P L+ + + + A+ Sbjct: 146 QALEEHLKAH-GPFINGQNISAADLSLAPKLYHLQVALEHFKGWKIPEDLTNVHAYTEAL 204 Query: 208 KWDPTVCALLMDKSIFQG 225 + K Sbjct: 205 FSRESFIKTKAAKEHLIA 222 >4PQI-A nrPDB Length = 241 Score = 167 bits (422), Expect = 5e-42, Method: Composition-based stats. Identities = 56/228 (24%), Positives = 96/228 (42%), Gaps = 19/228 (8%) Query: 12 GSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEV--VNINLRNKPEWYYTK-HP 68 QPP + +G ++Y+ CP++ R + K ++ E+ V + L+N+P WY K +P Sbjct: 23 AEQPP--LFDGTTKLYTCYTCPFAQRVWITRNFKGLQDEIKLVPLILQNRPAWYPEKVYP 80 Query: 69 FGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTK 128 +P LE ++ ES+ +YL+ + G L P DP A+++ ELF Sbjct: 81 PNKVPSLE-HNGKITGESLDLIKYLESNFEGPSLLPKDP---AKKEFAEELFSYTDKFNG 136 Query: 129 ECLVALRCGRECTNLKAALRQEFSNLEEIL-EYQNTTFFGGTCISMIDYLLWPWFERLDV 187 A + +L F +LE L ++ + FF G S++D P+ ERL++ Sbjct: 137 TVYTAFKG-----DLAKEAGPAFDHLENALHKFDDGPFFLGKEFSLVDIAYIPFVERLNI 191 Query: 188 YGI----LDCVSHTPALRLWISAMKWDPTVCALLMDKSIFQGFLNLYF 231 + + D + L WI + D F F Sbjct: 192 FLLEVFKYDITAGRQKLAAWIEEVNKIEAYKQTKTDPKELVEFYKKRF 239 >5LOL-A nrPDB Length = 215 Score = 166 bits (420), Expect = 7e-42, Method: Composition-based stats. Identities = 42/198 (21%), Positives = 74/198 (37%), Gaps = 16/198 (8%) Query: 32 CPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQLIYESVIACE 91 CP+S R L L+ K + ++ IN+ +KP+W+ P G +PV++ + + +S + Sbjct: 22 CPFSQRVLLTLEEKKLPYKTHLINVSDKPQWFLDISPEGKVPVVKL-DGKWVADSDVIVG 80 Query: 92 YLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECTNLKAALRQEF 151 L++ YP L E + + L+ + AL E Sbjct: 81 LLEEKYPEPSLKTPP-----------EFASVGSKIFGAFVTFLKSKDANDGSEKALVDEL 129 Query: 152 SNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDV----YGILDCVSHTPALRLWISAM 207 LE L+ + F G I+ +D L P L+V Y ++R + A+ Sbjct: 130 EALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKNWSVPESLTSVRNYAKAL 189 Query: 208 KWDPTVCALLMDKSIFQG 225 + K I Sbjct: 190 FSRESFENTKAKKEIVVA 207 >3IBH-A nrPDB Length = 233 Score = 166 bits (420), Expect = 7e-42, Method: Composition-based stats. Identities = 58/237 (24%), Positives = 82/237 (34%), Gaps = 21/237 (8%) Query: 1 MSGDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDI--RHEVVNINLRN 58 M+G G + + + IY PY R R+ L K++ + V INL Sbjct: 1 MNGRGFLIYNGGEK-----MKQKMIIYDTPAGPYPARVRIALAEKNMLSSVQFVRINLWK 55 Query: 59 ---KPEWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKM 115 K + K+ G +PVLE LI E EY+D L P E+ M Sbjct: 56 GEHKKPEFLAKNYSGTVPVLELDDGTLIAECTAITEYIDALDGTPTLTGKTPLEKGVIHM 115 Query: 116 L-----LELFCKVPHLTKECLVALRCGREC-TNLKAALRQEFSNLEEILEY----QNTTF 165 + LEL V L E N + LRQ L + + + + Sbjct: 116 MNKRAELELLDPVSVYFHHATPGLGPEVELYQNKEWGLRQRDKALHGMHYFDTVLRERPY 175 Query: 166 FGGTCISMIDYLLWPWFERLDVYGILDCVSHTPALRLWISAMKWDPTVCALLMDKSI 222 G SM D + + L ALR W M+ P+V LL +S Sbjct: 176 VAGDSFSMADITVIAGLIFAAIVK-LQVPEECEALRAWYKRMQQRPSVKKLLEIRSK 231 >5NR1-A nrPDB Length = 228 Score = 165 bits (418), Expect = 2e-41, Method: Composition-based stats. Identities = 48/208 (23%), Positives = 80/208 (38%), Gaps = 14/208 (6%) Query: 26 IYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQ---L 82 ++ P S + RL L K + + + P + + +P G PVL ++ Q + Sbjct: 7 LHHFPLDPASRQVRLALGEKRLPFVEMQVRYWEMPPEFTSLNPSGMPPVLVETKHQRNLV 66 Query: 83 IYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFC-----KVPHLTKECLVALRCG 137 I E+ E++++ L DP ERA + LL+ F +V + R Sbjct: 67 ICETRAILEHIEETETEPPLLGRDPAERAEARRLLQWFDRKFDNEVNGFLLHEKMEKRLL 126 Query: 138 RECTNLKAALRQEFSNLEEILEY-----QNTTFFGGTCISMIDYLLWPWFERLDVYGILD 192 R AALRQ L L Y Q + G +S+ D+ +D +G + Sbjct: 127 RMGAPDLAALRQGREALRMHLGYIESLLQTRDWLAGRRMSLADFAAAAHLSVIDYFGDVP 186 Query: 193 CVSHTPALRLWISAMKWDPTVCALLMDK 220 A + W +K P +L D+ Sbjct: 187 WK-DFQAAKTWYMKLKSRPCFRPILADR 213 >5IQY-A nrPDB Length = 216 Score = 164 bits (414), Expect = 4e-41, Method: Composition-based stats. Identities = 39/198 (19%), Positives = 71/198 (35%), Gaps = 16/198 (8%) Query: 32 CPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQLIYESVIACE 91 CP+S R L L+ K I +E+ ++L NKPEW+ P G +PV + + I +S + + Sbjct: 23 CPFSQRVLLTLEEKKITYEMKLVDLSNKPEWFLKISPEGKVPVFNSGDGKWIADSDVITQ 82 Query: 92 YLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECTNLKAALRQEF 151 +++ +P L Y K+ L+ + AL E Sbjct: 83 VIEEKFPTPSLVTPPEYASVGSKIFPSFVK-----------FLKSKDASDGSEKALLDEL 131 Query: 152 SNLEEILEYQNTTFFGGTCISMIDYLLWPWFER----LDVYGILDCVSHTPALRLWISAM 207 L+E L+ + G +S D L P L+ + + ++ + A+ Sbjct: 132 QALDEHLKAH-GPYISGENVSAADLSLGPKLFHLQVALEHFKGWKIPENLTSVHAYTKAL 190 Query: 208 KWDPTVCALLMDKSIFQG 225 + Sbjct: 191 FSRESFVKTKPANQYLIA 208 >1E6B-A nrPDB Length = 221 Score = 161 bits (406), Expect = 4e-40, Method: Composition-based stats. Identities = 47/212 (22%), Positives = 83/212 (39%), Gaps = 15/212 (7%) Query: 21 EGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPE---WYYTKHPFGHIPVLET 77 E +++YS +HR R+ L K + +E + +NL + + +P G +P L Sbjct: 6 EEKLKLYSYWRSSCAHRVRIALALKGLDYEYIPVNLLKGDQFDSDFKKINPMGTVPALVD 65 Query: 78 SQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCG 137 +I +S YLD+ YP L P D ++RA + + + L +R Sbjct: 66 GD-VVINDSFAIIMYLDEKYPEPPLLPRDLHKRAVNYQAMSIVLSGIQP-HQNLAVIRYI 123 Query: 138 RECTNLKA-------ALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFE-RLDVYG 189 E N++ A+ + F+ LE++L G I + D L P ++ + Sbjct: 124 EEKINVEEKTAWVNNAITKGFTALEKLLVNCAGKHATGDEIYLADLFLAPQIHGAINRFQ 183 Query: 190 ILDCVSHTPALRLWISAMKWDPTVCALLMDKS 221 I + P L + P L +K Sbjct: 184 IN--MEPYPTLAKCYESYNELPAFQNALPEKQ 213 >3PR8-A nrPDB Length = 229 Score = 160 bits (405), Expect = 4e-40, Method: Composition-based stats. Identities = 44/219 (20%), Positives = 87/219 (39%), Gaps = 15/219 (6%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQLI 83 +++Y Y + +L L K + E V P+ P G +PVLET + Sbjct: 3 LKLYGFSVSNYYNMVKLALLEKGLTFEEVTFYGGQAPQA-LEVSPRGKVPVLETEHG-FL 60 Query: 84 YESVIACEYLDDAYPGRKLFPYDPYERARQKMLL-ELFCKVPHLTKECLVALRCGRECTN 142 E+ + +Y++ G+ L P DP+ +A+ + LL E+ + + C G Sbjct: 61 SETSVILDYIEQTQGGKALLPADPFGQAKVRELLKEIELYIELPARTCYAESFFGMSVEP 120 Query: 143 L-----KAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYG----ILDC 193 L +A L F+ L+ + + G +++ D + + + G +D Sbjct: 121 LIKEKARADLLAGFATLKRNGRF--APYVAGEQLTLADLMFCFSVDLANAVGKKVLNIDF 178 Query: 194 VSHTPALRLWISAMKWDPTVCALLMDKSI-FQGFLNLYF 231 ++ P + + M +P + +L DK F+ + Sbjct: 179 LADFPQAKALLQLMGENPHMPRILADKEASMPAFMEMIR 217 >4AGS-A nrPDB Length = 471 Score = 160 bits (405), Expect = 4e-40, Method: Composition-based stats. Identities = 56/236 (23%), Positives = 96/236 (40%), Gaps = 18/236 (7%) Query: 4 DATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWY 63 + R L S P G + +YS FCP+ R RL + + + +V + L +PEWY Sbjct: 234 ENYRHLVPESAPMMGANGGHV-LYSNLFCPFVDRARLASELRKFQMHIVEVPLHPQPEWY 292 Query: 64 YTKHPFGHIPVLETSQCQLIYESVIACEYLD-DAYPGRKLFPYDPYERARQKMLLELFCK 122 +P +P L T + ++ES + +Y+D A G L P E+ + + F + Sbjct: 293 KYINPRDTVPALFTPSGEAVHESQLIVQYIDCVATKGSALVPRGDAEKEYE---VGFFVE 349 Query: 123 VPHLTKECLVA--LRCGRECTNLKAALRQEFSNLEEILE---YQNTTFFGGTCISMIDYL 177 L++ +R G + KA L+ LE+ L + FFGG ++ D Sbjct: 350 NAGYFVGGLMSWIIRGGEDA---KAELQWAAGELEQQLAKHPFGEGPFFGGKRMNAGDVA 406 Query: 178 LWPWFERLDVY-----GILDCVSHTPALRLWISAMKWDPTVCALLMDKSIFQGFLN 228 + P+ R + G D +H P L A P ++ ++ + Sbjct: 407 ILPFLVRAKAFMPEFSGGYDLFAHFPLLNGLAEAGMATPEAKSVFRTLEEYKEHIR 462 Score = 109 bits (273), Expect = 1e-24, Method: Composition-based stats. Identities = 43/224 (19%), Positives = 81/224 (36%), Gaps = 17/224 (7%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLR-NKPEWYYTKHPFGHIPVLETSQC-- 80 +++Y CP+ HR +V + K + ++ V + LR P+WY +P +P LE Sbjct: 27 LKLYVSATCPFCHRVEIVAREKQVSYDRVAVGLREEMPQWYKQINPRETVPTLEVGNADK 86 Query: 81 QLIYESVIACEYLDDA-YPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRE 139 + ++ES++ +YLD++ P L +R + + L L G + Sbjct: 87 RFMFESMLIAQYLDNSGAPAGALMGSSAAQRHQIEFFLAQVGDFIGAAHGLLRDPLSGEK 146 Query: 140 CTNLK--AALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLD----VYGILDC 193 + AA + ++ +M D L P+ RL Y D Sbjct: 147 RKAMDDNAAYVDGLLAANQ----TTGPYYCDGEFTMADVALVPFLVRLKPALMYYAGYDV 202 Query: 194 VSHTPALRLWISAMKWDPTVCALLMDKSIFQGFLNLYFQNNPNA 237 P ++ +A +V + + Y P + Sbjct: 203 FCKAPRMKALWAAAAQRASVRETSPTAAQC---IENYRHLVPES 243 >5N9U-A nrPDB Length = 218 Score = 149 bits (377), Expect = 9e-37, Method: Composition-based stats. Identities = 37/198 (18%), Positives = 70/198 (35%), Gaps = 17/198 (8%) Query: 32 CPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQLIYESVIACE 91 CP+ R L L+ K I ++ INL +KP+W+ P G +PV++ + + +S + Sbjct: 20 CPFCQRVLLSLEEKKIPYKSHLINLGDKPQWFLEISPEGKVPVVKIDD-KWVADSDVIVG 78 Query: 92 YLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECTNLKAALRQEF 151 L++ P L + K+ L+ + AL +E Sbjct: 79 ILEEKNPEPPLATPPEFASVGSKIFPSFVK-----------FLKSKDPNDGTEQALLEEL 127 Query: 152 SNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDV----YGILDCVSHTPALRLWISAM 207 L+ L+ F G I+ +D L P L+V + + + +I + Sbjct: 128 KALDGHLKVH-GPFIAGEKITAVDLSLAPKLYHLEVALGHFKNWPIPDNLTHVLNYIKLL 186 Query: 208 KWDPTVCALLMDKSIFQG 225 + + Sbjct: 187 FSRESFKKTRAAEEHVIA 204 >3TOT-A nrPDB Length = 226 Score = 148 bits (373), Expect = 2e-36, Method: Composition-based stats. Identities = 39/216 (18%), Positives = 80/216 (37%), Gaps = 12/216 (5%) Query: 23 LIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQL 82 ++++ PY+ + R+VL K I ++ V ++ N + +P G +P L Sbjct: 2 VMKLIGSHASPYTRKVRVVLAEKKIDYQFVLEDVWNADTQIHQFNPLGKVPCLVMDDGGA 61 Query: 83 IYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECTN 142 +++S + EY D P +L P ER + L + V Sbjct: 62 LFDSRVIAEYADTLSPVARLIPPSGRERVEVRCWEALADGLLDAAVALRVEQTQRTPEQR 121 Query: 143 LKAALRQEFSNLEEILEY-----QNTTFFGGTCISMIDYLLWPWFERLD-VYGILDCVSH 196 ++ + ++ ++E L+ + T+ G +++ D + LD +D Sbjct: 122 SESWITRQHHKIDEALKAMSRGLADRTWCNGNHLTLADIAVGCALAYLDFRQPQVDWREQ 181 Query: 197 TPALRLWISAMKWDPTVCALLMDKSIFQGFLNLYFQ 232 L + + ++ P+ NLYFQ Sbjct: 182 HANLAAFYTRIEKRPSFLETQPQAE------NLYFQ 211 >3M8N-A nrPDB Length = 225 Score = 147 bits (370), Expect = 5e-36, Method: Composition-based stats. Identities = 45/202 (22%), Positives = 87/202 (43%), Gaps = 15/202 (7%) Query: 22 GLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINL---RNKPEWYYTKHPFGHIPVLETS 78 L ++YSM+ S++ RL L D + V +++ ++ + K+P G +P+LET+ Sbjct: 2 SLYKLYSMQRSGNSYKVRLALALLDAPYRAVEVDILRGESRTPDFLAKNPSGQVPLLETA 61 Query: 79 QCQLIYESVIACEYLDDAYPGRKLFPYDPYERAR--QKMLLELFCKVPHLTKECLV--AL 134 + + ES YL G L P +RA Q M E P++ + Sbjct: 62 PGRYLAESNAILWYL---AVGTSLAPDTRMDRAEALQWMFFEQHALEPNIGSAYFWLCLV 118 Query: 135 RCGRECTN--LKAALRQEFSNLEEILEYQNTT-FFGGTCISMIDYLLWPWFERLDVYGIL 191 + GR+ L+ L + ++ L+ + + T +F +++ D L+ + D Sbjct: 119 KGGRDLQTHALEDWLERGYAALQVMENHLKTNDYFAAGQLTIADIALYGYTHVADQCDFD 178 Query: 192 DCVSHTPALRLWISAMKWDPTV 213 +S PA+ W+ ++ P Sbjct: 179 --LSTFPAVNAWLRRVEQTPGF 198 >4MK3-A nrPDB Length = 226 Score = 146 bits (368), Expect = 8e-36, Method: Composition-based stats. Identities = 35/203 (17%), Positives = 80/203 (39%), Gaps = 6/203 (2%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQLI 83 +++Y+ + PY+ + R+VL K I +E++ N+ + +P G +P L + Sbjct: 23 MKLYASQTSPYARKVRVVLAEKKIDYEMIEENVWSPDTTIGRFNPLGKVPCLVMEDGGAV 82 Query: 84 YESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECTNL 143 ++S + EY D P +L P ER + L + + + +E Sbjct: 83 FDSRVIAEYADTLSPVSRLIPQGSRERLEVRCWEALADGLLDAALLARLEVTQRKESERS 142 Query: 144 KAALRQEFSNLEEILEY-----QNTTFFGGTCISMIDYLLWPWFERLD-VYGILDCVSHT 197 ++ ++++ S ++ L + T+ GT ++ D + LD + + Sbjct: 143 ESWVQRQRSKIDAALTAMSTGLADKTWCTGTHYTLADVAVGCALAYLDFRFPDIAWRDRH 202 Query: 198 PALRLWISAMKWDPTVCALLMDK 220 P L + ++ + + Sbjct: 203 PNLVAFQEKIEKRQSFIDTEPPR 225 >1GWC-A nrPDB Length = 230 Score = 146 bits (368), Expect = 9e-36, Method: Composition-based stats. Identities = 49/216 (22%), Positives = 77/216 (35%), Gaps = 11/216 (5%) Query: 21 EGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPF-GHIPVLETSQ 79 +++ P+ R +L L K + +E V +L K E +P IPVL Sbjct: 4 GDDLKLLGAWPSPFVTRVKLALALKGLSYEDVEEDLYKKSELLLKSNPVHKKIPVL-IHN 62 Query: 80 CQLIYESVIACEYLDDAY--PGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCG 137 + ES+I +Y+D+ + G L P DPYERA + + + + Sbjct: 63 GAPVCESMIILQYIDEVFASTGPSLLPADPYERAIARFWVAYVDDKLVAPWRQWLRGKTE 122 Query: 138 RECTNLKAALRQEFSNLEEILEYQNT--TFFGGTCISMIDYLL---WPWFERLDVYGILD 192 E + K LE L + FFGG + ++D L W + + Sbjct: 123 EEKSEGKKQAFAAVGVLEGALRECSKGGGFFGGDGVGLVDVALGGVLSWMKVTEALSGDK 182 Query: 193 CV--SHTPALRLWISAMKWDPTVCALLMDKSIFQGF 226 + TP L W+ A L D F Sbjct: 183 IFDAAKTPLLAAWVERFIELDAAKAALPDVGRLLEF 218 >4IGJ-A nrPDB Length = 242 Score = 144 bits (362), Expect = 4e-35, Method: Composition-based stats. Identities = 47/210 (22%), Positives = 84/210 (40%), Gaps = 13/210 (6%) Query: 23 LIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEW---YYTKHPFGHIPVLETSQ 79 +R+YS + R RL L K + +E ++L + ++ + ++P +PVLE + Sbjct: 24 TLRLYSYWRSSSAWRVRLGLALKGLAYEYRAVDLLAQEQFQAAHQARNPMSQVPVLEVEE 83 Query: 80 C---QLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVA--L 134 L+ +S+ E+L++ +P L P D + RAR + L E + LV L Sbjct: 84 DGRTHLLVQSMAILEWLEERHPEPALLPPDLWGRARVRALAEHVNSGTQPMQNALVLRML 143 Query: 135 RCGRECTNLKAA---LRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGIL 191 R + + A + + + LE + F G ++ D L P +G+ Sbjct: 144 REKVPGWDREWARFFIARGLAALETAVRDGAGRFSHGDAPTLADCYLVPQLYNARRFGLD 203 Query: 192 DCVSHTPALRLWISAMKWDPTVCALLMDKS 221 + P LR A A D+ Sbjct: 204 --LEPYPTLRRVDEACAALAPFQAAHPDRQ 231 >1OYJ-A nrPDB Length = 231 Score = 130 bits (326), Expect = 6e-31, Method: Composition-based stats. Identities = 48/235 (20%), Positives = 80/235 (34%), Gaps = 33/235 (14%) Query: 21 EGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPF-GHIPVLETSQ 79 E + + P+ R R+ + K + E +L NK + +P IPVL Sbjct: 4 EKELVLLDFWVSPFGQRCRIAMAEKGLEFEYREEDLGNKSDLLLRSNPVHRKIPVL-LHA 62 Query: 80 CQLIYESVIACEYLDDAYPG-RKLFPY-------DPYERARQKMLLELFCKVPHLTKECL 131 + + ES++ +YLDDA+PG L P Y RA + + + + L Sbjct: 63 GRPVSESLVILQYLDDAFPGTPHLLPPANSGDADAAYARATARFWADYVDRKLYDCGSRL 122 Query: 132 VALRCGRECTNLKAALRQEFSNLEEILEYQNTTFFGGTC----------ISMIDYLLWP- 180 L+ +AA +E + + LE + G + +D L P Sbjct: 123 WRLKG-----EPQAAAGREMAEILRTLEAE-----LGDREFFGGGGGGRLGFVDVALVPF 172 Query: 181 --WFERLDVYGILDCVSHTPALRLWISAMKWDPTVCALLMDKSIFQGFLNLYFQN 233 WF + G P L W +V L F+ + + Sbjct: 173 TAWFYSYERCGGFSVEEVAPRLAAWARRCGRIDSVVKHLPSPEKVYDFVGVLKKK 227 >3UBL-A nrPDB Length = 242 Score = 127 bits (318), Expect = 6e-30, Method: Composition-based stats. Identities = 49/229 (21%), Positives = 88/229 (38%), Gaps = 23/229 (10%) Query: 23 LIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQL 82 +I+++ Y ++ +L + K + +E + I ++ E + P G IPVLE + Sbjct: 3 MIKLHGASISNYVNKVKLGILEKGLEYEQIRIAP-SQEEDFLKISPMGKIPVLEM-DGKF 60 Query: 83 IYESVIACEYLDDAYP-GRKLFPYDPYERARQK---MLLELFCKVPHLTKECLVALRCGR 138 I+ES E+LD +P KL P DP+E AR + ++E + +P A Sbjct: 61 IFESGAILEFLDTIFPQTPKLIPEDPWEAARVREISTIIETYLDIPARRIYLPAAKVSPE 120 Query: 139 ECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCVSHTP 198 + + L + L+ ++ + + G ++ D + LD ++ P Sbjct: 121 IVEEVHSTLVKGIKALQRVVRFS--PYIAGNVFTLADCSGFAHLSVLDEELRPFYPNNHP 178 Query: 199 --ALRLWISAM-------------KWDPTVCALLMDKSIFQGFLNLYFQ 232 L W K + +L G NLYFQ Sbjct: 179 LDLLNGWKEYFVFMKTKAGPALVEKDKQILKKILARAKTKIGAENLYFQ 227 >3NIV-A nrPDB Length = 222 Score = 124 bits (312), Expect = 3e-29, Method: Composition-based stats. Identities = 40/211 (18%), Positives = 74/211 (35%), Gaps = 18/211 (8%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNK-----PEWYYTKHPFGHIPVLETS 78 + +Y +R R+ L K I +E + ++L N Y+ +P +P L+ Sbjct: 3 LILYDYFRSTACYRVRIALNLKKIAYEKIEVHLVNNGGEQHSLQYHQINPQELVPSLDI- 61 Query: 79 QCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGR 138 Q++ +S+ +YL++ +P L P DP+ +A K + + H V R Sbjct: 62 NGQILSQSMAIIDYLEEIHPEMPLLPKDPFMKATLKSMALIVACDMHPLNNLRVLNRLKE 121 Query: 139 E--------CTNLKAALRQEFSNLEEILEY--QNTTFFGGTCISMIDYLLWPWFERLDVY 188 + L+ F EE L ++ G+ + + D L P + Sbjct: 122 QFNANEEQVLEWYHHWLKTGFDAFEEKLGALERDKPVCFGSEVGLADVCLIPQVYNAHRF 181 Query: 189 GILDCVSHTPALRLWISAMKWDPTVCALLMD 219 D S P + P + Sbjct: 182 -HFDMAS-YPIINEINEYCLTLPAFHDAAPE 210 >3LG6-A nrPDB Length = 235 Score = 124 bits (311), Expect = 4e-29, Method: Composition-based stats. Identities = 48/221 (21%), Positives = 80/221 (36%), Gaps = 23/221 (10%) Query: 16 PGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPE---WYYTKHPFGHI 72 PG + +Y S R R+ K I + +NL + Y + +P + Sbjct: 2 PGSMTTPNFELYGYFRSSCSGRLRIAFHLKSIPYTRHPVNLLKGEQHSDTYKSLNPTNTV 61 Query: 73 PVLETSQ----------CQLIYESVIACEYLDDAYPG--RKLFPY--DPYERARQKMLLE 118 P+L S I +S+ A EYL++A P R L P +P RA + + Sbjct: 62 PLLVVSNINNTVSPSSASFSIGQSLAALEYLEEALPTNARPLLPPISNPVARAHVRTICN 121 Query: 119 LFC----KVPHLTKECLVALRCGRECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMI 174 + V +L + V G + Q F +E++LE F G I++ Sbjct: 122 IIACDVQPVTNLKIQKKVKALDGDPTVWSRDLATQGFGAVEKLLELSAGRFCVGDEITLA 181 Query: 175 DYLLWPWFERLDVYGILDCVSHTPALRLWISAMKWDPTVCA 215 D L P + G+ ++ P + M + V Sbjct: 182 DVCLVPAVWAAERVGMD--LARFPITKRVFEEMLKEEAVQK 220 >2JL4-A nrPDB Length = 213 Score = 124 bits (310), Expect = 5e-29, Method: Composition-based stats. Identities = 39/209 (18%), Positives = 77/209 (36%), Gaps = 16/209 (7%) Query: 23 LIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP---EWYYTKHPFGHIPVLETSQ 79 +++Y+ SHR R+ L K + +E + ++L + + + +P +P L+T Sbjct: 1 KMKLYNFWRSGTSHRLRIALNLKGVPYEYLAVHLGKEEHLKDAFKALNPQQLVPALDTG- 59 Query: 80 CQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKEC----LVALR 135 Q++ +S E+L++ YP L P D R R + L + H + Sbjct: 60 AQVLIQSPAIIEWLEEQYPTPALLPADADGRQRVRALAAIVGCDIHPINNRRILEYLRKT 119 Query: 136 CGRECTNLKA----ALRQEFSNLEEILEYQ--NTTFFGGTCISMIDYLLWPWFERLDVYG 189 G + + A + F E +L + G ++ D L P E + Sbjct: 120 FGADEAAINAWCGTWISAGFDAYEALLAVDPKRGRYSFGDTPTLADCYLVPQVESARRFQ 179 Query: 190 ILDCVSHTPALRLWISAMKWDPTVCALLM 218 + ++ P +R +A Sbjct: 180 VD--LTPYPLIRAVDAACGELDAFRRAAP 206 >6JWK-A nrPDB Length = 222 Score = 120 bits (301), Expect = 5e-28, Method: Composition-based stats. Identities = 42/210 (20%), Positives = 76/210 (36%), Gaps = 14/210 (6%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWY---YTKHPFGHIPVLETSQC 80 +++YS S+R R+ L K + ++VV +NLR + ++P G +P L + Sbjct: 1 MQLYSFFNSSTSYRVRIALALKGLDYQVVPVNLRQGEQLRPADRQRNPMGALPTLVDADG 60 Query: 81 QLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLV-------- 132 + +S+ +YLD P +L P DP RA+ L L H V Sbjct: 61 RRFSQSLAIIDYLDAVQPEPRLIPLDPLHRAQALELALLVACDIHPLNNVRVLKYLTQVL 120 Query: 133 ALRCGRECTNLKAALRQEFSNLEEIL-EYQNTTFFGGTCISMIDYLLWPWFERLDVYGIL 191 + + + + E +L ++ FF G +++ L P G Sbjct: 121 GIDAEDRQRWYAHWVAEGLAAAETLLNRHRRGAFFAGAAAGIVECCLVPQLANARRMGCD 180 Query: 192 DCVSHTPALRLWISAMKWDPTVCALLMDKS 221 ++ PAL ++ Sbjct: 181 --LAPYPALLELEGRCLALEAFQRASPERQ 208 >4PXO-A nrPDB Length = 238 Score = 120 bits (301), Expect = 5e-28, Method: Composition-based stats. Identities = 42/215 (19%), Positives = 76/215 (35%), Gaps = 15/215 (6%) Query: 20 PEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLR---NKPEWYYTKHPFGHIPVLE 76 + ++++Y + R R+ L K I +E V ++L + +P G +P L Sbjct: 20 FQSMVKMYGNWRSAAAFRVRIALNLKGIAYEEVFLDLDAGDQHKPDFLAINPQGAVPALF 79 Query: 77 TSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLE--------LFCKVPHLTK 128 + +S+ +YL++ G L P +P RAR + L + L+ Sbjct: 80 DGDGPPLTQSLAILDYLEETRTGVPLLPEEPRARARARSLAQVVACDTHPLYVPRVRTFL 139 Query: 129 ECLVALRCGRECTNLKAALRQEFSNLEEILEYQNTT--FFGGTCISMIDYLLWPWFERLD 186 L R L+ A LE L + T F G +S D L + Sbjct: 140 MENYGLPRERMLEFLRNAFITGLKTLETRLSNEAGTGRFCQGDAVSHADLCLISLWVGTG 199 Query: 187 VYGILDCVSHTPALRLWISAMKWDPTVCALLMDKS 221 ++GI + P ++ + V + Sbjct: 200 IFGID--TAAYPTVKRISEEVLALDAVARAHPLRQ 232 >3M3M-A nrPDB Length = 210 Score = 118 bits (295), Expect = 3e-27, Method: Composition-based stats. Identities = 42/209 (20%), Positives = 83/209 (39%), Gaps = 18/209 (8%) Query: 22 GLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLR---NKPEWYYTKHPFGHIPVLETS 78 L ++Y ++ +L+L + +E +++ + E + K+P G IPVLE Sbjct: 2 SLYKVYGDYRSGNCYKIKLMLNLLGLPYEWQAVDILGGDTQTEAFLAKNPNGKIPVLELE 61 Query: 79 QCQLIYESVIACEYLDDAYPGRKLFPYDPYERAR--QKMLLELFCKVPHLTKECLVALRC 136 ++ES +L D G + P +P R + Q E + P++ + L Sbjct: 62 DGTCLWESNAILNFLAD---GSQFLPSEPRLRTQVLQWQFFEQYSHEPYIAVARFIQLYE 118 Query: 137 GRECTNLKAALR------QEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGI 190 G + L+ + +E+ L T + G S+ D L+ + D G Sbjct: 119 GLPEERREEYLKLHKRGYKALDVMEKQL--SRTPYLVGEHYSIADIALYAYTHVADEGGF 176 Query: 191 LDCVSHTPALRLWISAMKWDPTVCALLMD 219 +S P ++ W+ ++ P +L + Sbjct: 177 D--LSRYPGIQAWMQRVQSHPRHVPMLDE 203 >3VWX-A nrPDB Length = 222 Score = 110 bits (275), Expect = 5e-25, Method: Composition-based stats. Identities = 45/199 (22%), Positives = 78/199 (39%), Gaps = 13/199 (6%) Query: 22 GLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNK---PEWYYTKHPFGHIPVLETS 78 G + +Y + P L LKA ++ E +NL K E Y K+P +P LE Sbjct: 2 GKLVLYGIDPSPPVRACLLTLKALNLPFEYKVVNLFAKEHLSEEYLKKNPQHTVPTLE-E 60 Query: 79 QCQLIYESVIACEYLDDAYP-GRKLFPYDPYERAR--QKMLLELFCKVPHLTKECLVALR 135 LI++S YL Y L+P D +RA Q+M E + L Sbjct: 61 DGHLIWDSHAIMAYLVSKYGKDDSLYPKDLLKRAVVDQRMYFEAGVLFQGGLRNITAPLF 120 Query: 136 CGRECTNLKA---ALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILD 192 + + ++ + + LE L+ + G +++ D+ + L + +D Sbjct: 121 FRNQTQIPQHQIDSIVESYGFLESFLKN--NKYMAGDHLTIADFSIVTSVTSLVAFAEID 178 Query: 193 CVSHTPALRLWISAMKWDP 211 S P L W+ +++ P Sbjct: 179 -QSKFPKLSAWLKSLQSLP 196 >4PNG-A nrPDB Length = 229 Score = 110 bits (274), Expect = 7e-25, Method: Composition-based stats. Identities = 46/218 (21%), Positives = 87/218 (39%), Gaps = 14/218 (6%) Query: 23 LIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNK---PEWYYTKHPFGHIPVLETSQ 79 + +Y + P +L L A ++ +E V +N R K E + K+P +P LE Sbjct: 9 KLILYGLEASPPVRAVKLTLAALEVPYEFVEVNTRAKENFSEEFLKKNPQHTVPTLE-DD 67 Query: 80 CQLIYESVIACEYLDDAYPGR-KLFPYDPYERAR--QKMLLELFCKVPHLTKECLVALRC 136 I++S YL Y L+P D +RA Q++ E + + L Sbjct: 68 GHYIWDSHAIIAYLVSKYGKTDSLYPKDLLQRAVVDQRLHFESGVIFANALRSITKPLFA 127 Query: 137 GRECTNLKA---ALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDC 193 G++ K A+ + + LE+ L + G +++ D+ + L+V+ +D Sbjct: 128 GKQTMIPKERYDAIIEVYDFLEKFLA--GNDYVAGNQLTIADFSIISTVSSLEVFVKVD- 184 Query: 194 VSHTPALRLWISAMKWDPTVCALLMD-KSIFQGFLNLY 230 + P + W ++ P + F+ F+ Y Sbjct: 185 TTKYPRIAAWFKRLQKLPYYEEANGNGARTFESFIREY 222 >4YH2-A nrPDB Length = 222 Score = 109 bits (273), Expect = 9e-25, Method: Composition-based stats. Identities = 43/198 (21%), Positives = 81/198 (40%), Gaps = 13/198 (6%) Query: 23 LIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNK---PEWYYTKHPFGHIPVLETSQ 79 + +Y + P +L L A ++ +E VN+++ + Y K+P +P LE Sbjct: 3 KLTLYGLDPSPPVRAVKLTLAALNLTYEYVNVDIVARAQLSPEYLEKNPQHTVPTLE-DD 61 Query: 80 CQLIYESVIACEYLDDAYPGR-KLFPYDPYERARQKMLLELFCKVPHLTKECLVA---LR 135 I++S YL Y L+P DP +RA L V ++ L Sbjct: 62 GHYIWDSHAIIAYLVSKYADSDALYPKDPLKRAVVDQRLHFESGVVFANGIRSISKSVLF 121 Query: 136 CGRECTNLK--AALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDC 193 G+ + A+ + + +E L+ Q+ + G +++ D+ L L+ + LD Sbjct: 122 QGQTKVPKERYDAIIEIYDFVETFLKGQD--YIAGNQLTIADFSLVSSVASLEAFVALD- 178 Query: 194 VSHTPALRLWISAMKWDP 211 + P + WI ++ P Sbjct: 179 TTKYPRIGAWIKKLEQLP 196 >1AW9-A nrPDB Length = 216 Score = 108 bits (270), Expect = 2e-24, Method: Composition-based stats. Identities = 41/208 (19%), Positives = 76/208 (36%), Gaps = 15/208 (7%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINL---RNKPEWYYTKHPFGHIPVLETSQC 80 +++Y M P R VL K + E+V ++L +K + +PFG IP L Sbjct: 3 LKLYGMPLSPNVVRVATVLNEKGLDFEIVPVDLTTGAHKQPDFLALNPFGQIPALVDGD- 61 Query: 81 QLIYESVIACEYLDDAY--PGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVA---LR 135 ++++ES Y+ Y G L P A+ ++ LE+ + LV +R Sbjct: 62 EVLFESRAINRYIASKYASEGTDLLPAT-ASAAKLEVWLEVESHHFYPNASPLVFQLLVR 120 Query: 136 CGRECTNLKAALRQEFSNLEEILEYQN-----TTFFGGTCISMIDYLLWPWFERLDVYGI 190 A + + L ++L+ + G ++ D + L Sbjct: 121 PLLGGAPDAAVVDKHAEQLAKVLDVYEAHLARNKYLAGDEFTLADANHASYLLYLSKTPK 180 Query: 191 LDCVSHTPALRLWISAMKWDPTVCALLM 218 V+ P ++ W A+ P + Sbjct: 181 AGLVAARPHVKAWWEAIVARPAFQKTVA 208 >3R2Q-A nrPDB Length = 202 Score = 108 bits (270), Expect = 2e-24, Method: Composition-based stats. Identities = 31/202 (15%), Positives = 66/202 (32%), Gaps = 6/202 (2%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQLI 83 +++ P+ + ++L K I E +N N +P G +PVL T + + Sbjct: 1 MKLVGSYTSPFVRKLSILLLEKGITFEFINELPYNADNGVAQFNPLGKVPVLVTEEGECW 60 Query: 84 YESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECTNL 143 ++S I EY++ + P DP E R + + L + V + Sbjct: 61 FDSPIIAEYIELMNVAPAMLPRDPLESLRVRKIEALADGIMDAGL-VSVREQARPAAQQS 119 Query: 144 KAALRQEFSNLEEILEYQNTTFFGG----TCISMIDYLLWPWFERLDVYGILD-CVSHTP 198 + L ++ + L+ G +++ + L+ + P Sbjct: 120 EDELLRQREKINRSLDVLEGYLVDGTLKTDTVNLATIAIACAVGYLNFRRVAPGWCVDRP 179 Query: 199 ALRLWISAMKWDPTVCALLMDK 220 L + + + K Sbjct: 180 HLVKLVENLFSRESFARTEPPK 201 >5F06-A nrPDB Length = 216 Score = 107 bits (266), Expect = 5e-24, Method: Composition-based stats. Identities = 38/209 (18%), Positives = 77/209 (36%), Gaps = 17/209 (8%) Query: 23 LIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINL----RNKPEWYYTKHPFGHIPVLETS 78 ++++Y + R L K++ E+V ++L +P + K+PFG IP LE Sbjct: 1 VLKLYGAPMSTCTSRVLTCLHEKNLDFELVPVDLFAGEHKQPP-FLAKNPFGQIPALEED 59 Query: 79 QCQLIYESVIACEYLDDAYPGRK---LFPYDPYERARQKMLLELFCKVPHLTKECLVALR 135 ++ES Y+ + + G + + E A K+ E+ + +V Sbjct: 60 DLT-LFESRAITSYIAEKFKGTGYDLIRHENLKEAASVKVWTEVESHRYNPAIAPIVFQF 118 Query: 136 C---GRECTNLKAALRQEFSNLEEIL-----EYQNTTFFGGTCISMIDYLLWPWFERLDV 187 R + + + L ++L + +T + G S+ D P+ L Sbjct: 119 MVAPLRGNSPDQTIIDDNVEKLGKVLDIYEAKLSSTKYLAGDFYSLADLHHLPYTYYLMK 178 Query: 188 YGILDCVSHTPALRLWISAMKWDPTVCAL 216 V+ P ++ W + P + Sbjct: 179 TPAASVVNERPHVKAWWEDISSRPAFKKV 207 >3UAR-A nrPDB Length = 227 Score = 97.1 bits (240), Expect = 6e-21, Method: Composition-based stats. Identities = 46/216 (21%), Positives = 81/216 (37%), Gaps = 11/216 (5%) Query: 23 LIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPE----WYYTKHPFGHIPVLETS 78 ++++Y S +VL+ + E+ N++L K + +P G++P L+ Sbjct: 2 VMKLYYFP-GACSLAPHIVLREAGLDFELENVDLGTKKTGSGADFLQVNPKGYVPALQLD 60 Query: 79 QCQLIYESVIACEYLDDAYPGRKLFPY-DPYERARQKMLLELFCKVPHLTKECLVALRCG 137 Q++ E + +YL D P L P +ER R L H T Sbjct: 61 DGQVLTEDQVILQYLADLKPESGLMPPSGTFERYRLLEWLAFISTEIHKTFGPFWNPESP 120 Query: 138 RECTNLKAALR-QEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCVSH 196 + L + +E+ LE + G S+ D L + I +S Sbjct: 121 EASKQIALGLLSRRLDYVEDRLEA-GGPWLMGDRYSVADAYLSTVLGWCEYLKID--LSK 177 Query: 197 TPALRLWISAMKWDPTVCALLMDKSIFQGFLNLYFQ 232 P + ++ + P V A + + + Q NLYFQ Sbjct: 178 WPRILAYLERNQARPAVQAAMKAEGLIQA-ENLYFQ 212 >5F07-A nrPDB Length = 213 Score = 96.3 bits (238), Expect = 1e-20, Method: Composition-based stats. Identities = 40/211 (18%), Positives = 76/211 (36%), Gaps = 19/211 (9%) Query: 23 LIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINL---RNKPEWYYTKHPFGHIPVLETSQ 79 ++++Y R L K + ++V+++L K + K PFG +PV+E Sbjct: 1 VVKVYGPAVAVCPQRVMACLLEKGVEFDLVHVDLDSGEQKLPEFLLKQPFGQVPVVEDGD 60 Query: 80 CQLIYESVIACEYLDDAYP--GRKLFPYDPYERARQKMLLE-----LFCKVPHLTKECLV 132 + ++ES Y Y G L E+A LE V ++ + ++ Sbjct: 61 FK-LFESRAIIRYYAAKYEDRGPNLLGNTLEEKALVDQWLEIEAHNFNDLVFNIVFQVVI 119 Query: 133 ALRCGRECTNL-----KAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERL-D 186 R G++ + + L + E+ L + + G ++ D P L + Sbjct: 120 LPRIGQQGDSELVRTYEEKLEKVLDVYEKRL--SKSKYLAGDSFTLADLSHLPATRYLVN 177 Query: 187 VYGILDCVSHTPALRLWISAMKWDPTVCALL 217 G+ V L W + P L+ Sbjct: 178 EAGLGHLVKDRKKLNAWWEDISSRPAWKKLM 208 >5A5K-A nrPDB Length = 212 Score = 93.6 bits (231), Expect = 7e-20, Method: Composition-based stats. Identities = 35/209 (16%), Positives = 80/209 (38%), Gaps = 17/209 (8%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRN---KPEWYYTKHPFGHIPVLETSQC 80 I+++ + R + L K++ E+V++ L++ K E + +++PFG +P E Sbjct: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDL 63 Query: 81 QLIYESVIACEYLDDAYP--GRKLFPYDPY---ERARQKMLLELFCKVPHLTKECLVA-- 133 + ++ES +Y+ Y G L D + A + +++ L Sbjct: 64 K-LFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQ 122 Query: 134 -LRCGRECTNLKAALRQEFSNLEEILEYQNT-----TFFGGTCISMIDYLLWPWFERLDV 187 + T +A + +E + L ++L+ + G ++ D P + L Sbjct: 123 IFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLG 182 Query: 188 YGILDCVSHTPALRLWISAMKWDPTVCAL 216 + P + W++ + P + Sbjct: 183 TPTKKLFTERPRVNEWVAEITKRPASEKV 211 >4RI7-A nrPDB Length = 215 Score = 92.1 bits (227), Expect = 2e-19, Method: Composition-based stats. Identities = 38/208 (18%), Positives = 68/208 (32%), Gaps = 13/208 (6%) Query: 26 IYSMRFCPYSHRTRLVLKAKDIRHEVVNINLR---NKPEWYYTKHPFGHIPVLETSQCQL 82 IY C R L KD+ ++ I+L K Y PFG +P + Sbjct: 7 IYGPPLCTAVSRVLATLIEKDVPFHLIPIDLSKGEQKKPEYLKIQPFGQVPAFKDESIT- 65 Query: 83 IYESVIACEYLDDAYPG---RKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRE 139 ++ES C Y+ D Y + L+ D +A +E + LV Sbjct: 66 LFESRAICRYICDKYADKGNKSLYGTDILSKANIDQWVETDGQTFGPPSGDLVHDLLFSS 125 Query: 140 CTNLKAALRQEFSNLEEIL-----EYQNTTFFGGTCISMIDYLLWP-WFERLDVYGILDC 193 +A +++ L ++L + T F G S D P ++ Sbjct: 126 VPVDEALIKKNVDKLAKVLDIYEQKLGQTRFLAGDEFSFADLSHLPNGDYLVNSTDKGYL 185 Query: 194 VSHTPALRLWISAMKWDPTVCALLMDKS 221 + + W + + + +L + Sbjct: 186 FTSRKNVNRWWTEISNRESWKKVLEMRK 213 >2GDR-A nrPDB Length = 202 Score = 91.7 bits (226), Expect = 2e-19, Method: Composition-based stats. Identities = 40/205 (19%), Positives = 82/205 (40%), Gaps = 21/205 (10%) Query: 24 IRIY----SMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP----EWYYTKHPFGHIPVL 75 +++Y + P+ + L+ + E+V ++L +K + Y +P G++P L Sbjct: 1 MKLYYSPGACSLSPH-----IALREAGLNFELVQVDLASKKTASGQDYLEVNPAGYVPCL 55 Query: 76 ETSQCQLIYESVIACEYLDDAYPGRKLFPY-DPYERARQKMLLELFCKVPHLTKECLVAL 134 + + + E +Y+ D PG++L P +ER + L H + L Sbjct: 56 QLDDGRTLTEGPAIVQYVADQVPGKQLAPANGSFERYHLQQWLNFISSELHKSFSPLFNP 115 Query: 135 RCGRECTN-LKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDC 193 E N ++ +L + LE+ + G +S+ D L F L ++ Sbjct: 116 ASSDEWKNAVRQSLNTRLGQVARQLEH--APYLLGDQLSVADIYL---FVVLGWSAYVNI 170 Query: 194 -VSHTPALRLWISAMKWDPTVCALL 217 +S P+L+ + + V + L Sbjct: 171 DLSPWPSLQAFQGRVGGREAVQSAL 195 >3C8E-A nrPDB Length = 288 Score = 91.3 bits (225), Expect = 3e-19, Method: Composition-based stats. Identities = 37/242 (15%), Positives = 77/242 (31%), Gaps = 33/242 (13%) Query: 2 SGDATRTLGKGSQPP-----GPVPEGLIRIYSMRFCPYSHRTRLVLKAK------DIRHE 50 +G A + + P PV + +++YS+ P + ++L+ ++ Sbjct: 18 AGGAFANINRPVSGPTHEKTLPVGKHPLQLYSLGT-PNGQKVTIMLEELLALGVTGAEYD 76 Query: 51 VVNINLRNKPEW---YYTKHPFGHIPVLETSQCQL---IYESVIACEYLDDAYPGRKLFP 104 I + + ++ + +P IP L ++ES YL + + P Sbjct: 77 AWLIRIGDGDQFSSGFVEVNPNSKIPALRDHTHNPPIRVFESGSILLYLAEKFG--YFLP 134 Query: 105 YDPYERARQKMLLELFCKVPHLTKECL------VALRCGRECTNLKAALRQEFSNLEEIL 158 D +R L ++ ++ L++ L Sbjct: 135 QDLAKRTETMNWLFWLQGAAPFLGGGFGHFYHYAPVKIEYAINRFTMEAKRLLDVLDKQL 194 Query: 159 EYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCVSHTPA-----LRLWISAMKWDPTV 213 F G ++ D +WPWF + + G+ D A ++ W + P V Sbjct: 195 AQH--KFVAGDEYTIADMAIWPWFGNVVLGGVYDAAEFLDAGSYKHVQRWAKEVGERPAV 252 Query: 214 CA 215 Sbjct: 253 KR 254 >5EY6-A nrPDB Length = 217 Score = 89.4 bits (220), Expect = 1e-18, Method: Composition-based stats. Identities = 35/215 (16%), Positives = 74/215 (34%), Gaps = 20/215 (9%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRN---KPEWYYTKHPFGHIPVLETSQC 80 +++Y R + L KD+ +++ +++ K Y PFG +P + Sbjct: 4 VKVYGPPLSTAVSRVLVTLLEKDVPFQIIPVDMSKGEHKKPDYLKIQPFGQVPAFQDESI 63 Query: 81 QLIYESVIACEYLDDAY---PGRKLFPYDPYERARQKMLLELFCKVPHLTKECLV---AL 134 ++ES C Y+ + Y + L+ +P ERA +E + + LV A Sbjct: 64 S-LFESRSICRYVCEKYADRGDKGLYGTNPLERASIDQWVEAEGQSFGPSSGALVFQLAF 122 Query: 135 RCGRECTNLKAALRQEFSNLEEIL-----EYQNTTFFGGTCISMIDYLLWP---WFERLD 186 + ++Q L ++L + F G + D P + Sbjct: 123 APRMNIPQDQGVIKQNEEKLGKVLDIYEQRLGESRFLAGDEFTFADLSHLPNGDYLVNAT 182 Query: 187 VYGILDCVSHTPALRLWISAMKWDPTVCALLMDKS 221 G L + + W + + + ++ + Sbjct: 183 DKGHL--FTSRENVGRWWNEISDRESWKKVIEMRK 215 >2IL3-A nrPDB Length = 221 Score = 88.6 bits (218), Expect = 2e-18, Method: Composition-based stats. Identities = 42/198 (21%), Positives = 74/198 (37%), Gaps = 17/198 (8%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP---EWYYTKHPFGHIPVLETSQC 80 + +Y++ P L KA + E INL + +P IPVL Sbjct: 4 LVLYTLHLSPPCRAVELTAKALGLELEQKTINLLTGDHLKPEFVKLNPQHTIPVL-DDNG 62 Query: 81 QLIYESVIACEYLDDAYP-GRKLFPYDPYERARQKMLLEL-----FCKVPHLTKECLVAL 134 +I ES YL Y L+P DP ++AR L F ++ + + L Sbjct: 63 TIITESHAIMIYLVTKYGKDDSLYPKDPVKQARVNSALHFESGVLFARMRFIFERILFFG 122 Query: 135 RCGRECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCV 194 + ++ +++ + LE+ L F G +++ D+ + G++ Sbjct: 123 KSDIPEDRVEY-VQKSYELLEDTLV---DDFVAGPTMTIADFSCISTIS--SIMGVVPLE 176 Query: 195 -SHTPALRLWISAMKWDP 211 S P + WI +K P Sbjct: 177 QSKHPRIYAWIDRLKQLP 194 >4IKH-A nrPDB Length = 244 Score = 88.2 bits (217), Expect = 3e-18, Method: Composition-based stats. Identities = 35/225 (15%), Positives = 77/225 (34%), Gaps = 24/225 (10%) Query: 20 PEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLR---NKPEWYYTKHPFGHIPVLE 76 I++YS+ P + ++L+ + +E ++ + + P IP + Sbjct: 19 FPEWIQLYSLPT-PNGVKVSIMLEEIGLPYEAHRVSFETQDQMTPEFLSVSPNNKIPAIL 77 Query: 77 TSQC-----QLIYESVIACEYLDDAYPGRKLFPYDPYERAR--QKMLLELFCKVPHLTKE 129 ++ES YL D +L + R Q ++ ++ P + Sbjct: 78 DPHGPGDQPLALFESGAILIYLADKSG--QLLAQESAARYETIQWLMFQMGGIGPMFGQV 135 Query: 130 CLVALRCGRECTNLK------AALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFE 183 GRE + + ++ L++ L + G ++ D +PW Sbjct: 136 GFFNKFAGREYEDKRPLERYVNEAKRLLGVLDKHL--GGREWIMGERYTIADIATFPWIR 193 Query: 184 RLDVY---GILDCVSHTPALRLWISAMKWDPTVCALLMDKSIFQG 225 L + G L + + P ++ ++ P V L + +G Sbjct: 194 NLIGFYEAGELVGIDNFPEVKRVLAKFVARPAVIRGLEIPKVSEG 238 >1AXD-A nrPDB Length = 209 Score = 87.9 bits (216), Expect = 3e-18, Method: Composition-based stats. Identities = 37/209 (17%), Positives = 74/209 (35%), Gaps = 18/209 (8%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINL---RNKPEWYYTKHPFGHIPVLETSQC 80 +++Y R L+ +E+V IN +K + ++PFG +P L+ Sbjct: 3 MKLYGAVMSWNLTRCATALEEAGSDYEIVPINFATAEHKSPEHLVRNPFGQVPALQDGD- 61 Query: 81 QLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLEL------FCKVPHLTKECLVAL 134 ++ES C+Y L + E A + +E+ P L + + + Sbjct: 62 LYLFESRAICKYAARKNKPELLREGNLEEAAMVDVWIEVEANQYTAALNPILFQVLISPM 121 Query: 135 RCGRECTNLKAALRQEFSNLEEILEYQNT-----TFFGGTCISMIDYLLWPWFERLDVYG 189 G T + + + L+++LE + G +S+ D L Sbjct: 122 LGG---TTDQKVVDENLEKLKKVLEVYEARLTKCKYLAGDFLSLADLNHVSVTLCLFATP 178 Query: 190 ILDCVSHTPALRLWISAMKWDPTVCALLM 218 + P ++ W S + P+V + Sbjct: 179 YASVLDAYPHVKAWWSGLMERPSVQKVAA 207 >6F05-A nrPDB Length = 215 Score = 86.3 bits (212), Expect = 1e-17, Method: Composition-based stats. Identities = 37/213 (17%), Positives = 70/213 (32%), Gaps = 22/213 (10%) Query: 23 LIRIYS-MRFCPYSHRTRLVLKAKDIRHEVVNINLRN---KPEWYYTKHPFGHIPVLETS 78 ++++Y P R + L K + E + ++L K Y PFG +P + Sbjct: 2 VLKVYGPHFASP--KRALVTLIEKGVAFETIPVDLMKGEHKQPAYLALQPFGTVPAVVDG 59 Query: 79 QCQLIYESVIACEYLDDAY--PGRKLFPYDPYERARQKMLLE-----LFCKVPHLTKECL 131 + I+ES Y+ + Y G L +R + + L+ + +LT + Sbjct: 60 DYK-IFESRAVMRYVAEKYRSQGPDLLGKTVEDRGQVEQWLDVEATTYHPPLLNLTLHIM 118 Query: 132 VALRCGRECT-----NLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERL- 185 A G + L E L + + G +S+ D P+ + L Sbjct: 119 FASVMGFPSDEKLIKESEEKLAGVLDVYEAHL--SKSKYLAGDFVSLADLAHLPFTDYLV 176 Query: 186 DVYGILDCVSHTPALRLWISAMKWDPTVCALLM 218 G + + W + P + Sbjct: 177 GPIGKAYMIKDRKHVSAWWDDISSRPAWKETVA 209 >1JLV-A nrPDB Length = 209 Score = 85.9 bits (211), Expect = 1e-17, Method: Composition-based stats. Identities = 34/213 (15%), Positives = 68/213 (31%), Gaps = 13/213 (6%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINL---RNKPEWYYTKHPFGHIPVLETSQC 80 + Y + ++ A + + NL + + +P IP L Sbjct: 1 MDFYYLPGSAPCRAVQMTAAAVGVELNLKLTNLMAGEHMKPEFLKINPQHCIPTLV-DNG 59 Query: 81 QLIYESVIACEYLDDAYP-GRKLFPYDPYERAR--QKMLLELFCKVPHLTKECLVALRCG 137 ++ES C YL + Y KL+P DP +RA Q++ ++ + Sbjct: 60 FALWESRAICTYLAEKYGKDDKLYPKDPQKRAVVNQRLYFDMGTLYQRFADYYYPQIFAK 119 Query: 138 RE-CTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCVSH 196 + + ++ L L+ + G +++ D + DV G ++ Sbjct: 120 QPANAENEKKMKDAVDFLNTFLDGH--KYVAGDSLTIADLTVLATVSTYDVAGFE--LAK 175 Query: 197 TPALRLWISAM-KWDPTVCALLMDKSIFQGFLN 228 P + W K P F+ + Sbjct: 176 YPHVAAWYERTRKEAPGAAINEAGIEEFRKYFE 208 >1F2E-A nrPDB Length = 201 Score = 85.6 bits (210), Expect = 2e-17, Method: Composition-based stats. Identities = 35/186 (18%), Positives = 64/186 (34%), Gaps = 14/186 (7%) Query: 40 LVLKAKDIRHEVVNINLR----NKPEWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDD 95 + L+ E V ++L E + T +P G +P L + + E+ Y+ D Sbjct: 16 IALRETGADFEAVKVDLAVRKTEAGEDFLTVNPSGKVPALTLDSGETLTENPAILLYIAD 75 Query: 96 AYPGRKLFPY----DPYERARQKMLLELFCKVPHLTKECLVALRCGRECTNLKAALRQEF 151 P L P D Y R ++ L + +++ Sbjct: 76 QNPASGLAPAEGSLDRY-RLLSRLSF-LGSEFHKAFVPLFAPATSDEAKAAAAESVKNHL 133 Query: 152 SNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCVSHTPALRLWISAMKWDP 211 + L++ L ++ + G S+ D L+ GI ++ PAL + + P Sbjct: 134 AALDKELAGRD--HYAGNAFSVADIYLYVMLGWPAYVGID--MAAYPALGAYAGKIAQRP 189 Query: 212 TVCALL 217 V A L Sbjct: 190 AVGAAL 195 >2PMT-A nrPDB Length = 203 Score = 84.0 bits (206), Expect = 5e-17, Method: Composition-based stats. Identities = 41/212 (19%), Positives = 81/212 (38%), Gaps = 19/212 (8%) Query: 24 IRIY----SMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPE----WYYTKHPFGHIPVL 75 +++Y S P+ +VL+ + + I+LR K + +P G +PVL Sbjct: 1 MKLYYTPGSCSLSPH-----IVLRETGLDFSIERIDLRTKKTESGKDFLAINPKGQVPVL 55 Query: 76 ETSQCQLIYESVIACEYLDDAYPGRKLF-PYDPYERARQKMLLELFCKVPHLTKECLVAL 134 + ++ E V +YL D P R L P ER Q L H L + Sbjct: 56 QLDNGDILTEGVAIVQYLADLKPDRNLIAPPKALERYHQIEWLNFLASEVHKGYSPLFSS 115 Query: 135 RCGRE-CTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDC 193 +K L+ +F + ++L Q G ++ D L+ + + Sbjct: 116 DTPESYLPVVKNKLKSKFVYINDVLSKQKC--VCGDHFTVADAYLFTLSQWAPHVALD-- 171 Query: 194 VSHTPALRLWISAMKWDPTVCALLMDKSIFQG 225 ++ L+ +++ + P V + L+ + + + Sbjct: 172 LTDLSHLQDYLARIAQRPNVHSALVTEGLIKE 203 >3LSZ-A nrPDB Length = 225 Score = 83.6 bits (205), Expect = 6e-17, Method: Composition-based stats. Identities = 38/218 (17%), Positives = 66/218 (30%), Gaps = 26/218 (11%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNI--------------NLRNKPEWYYTKHPF 69 ++IY + S L L D+ E V + L Y +P Sbjct: 3 LKIYGVYRSRASRPLWL-LAELDLPFEHVPVIQANRVAHPHGPEAPLNTASAAYLAVNPL 61 Query: 70 GHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERA--RQKMLLELFCKVPHLT 127 G IP LE + ++ ES+ ++ G +L P E A L P Sbjct: 62 GQIPCLE-EEGLILTESLAITLHIARTQGG-QLGPRSEPEDALMVSWSLFAATAVEPPAL 119 Query: 128 KECLVALRCGRECTNLKAALRQEFSNLEEIL-----EYQNTTFFGGTCISMIDYLLWPWF 182 + L+ G +AA+ L L + + G ++ D L Sbjct: 120 EIQLIQRSGGGTSPEGQAAIAIAAERLRRPLARLERHFAAEDYLVGGRFTVADLNLAETL 179 Query: 183 ERLDVYGILDCVSHTPALRLWISAMKWDPTVCALLMDK 220 + PA+ W+ + P ++ + Sbjct: 180 RYGQA--HPALLEPFPAVAAWLDRCQSRPAFRLMMERR 215 >3GX0-A nrPDB Length = 215 Score = 83.6 bits (205), Expect = 6e-17, Method: Composition-based stats. Identities = 37/208 (17%), Positives = 73/208 (35%), Gaps = 18/208 (8%) Query: 23 LIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNK---PEWYYTKHPFGHIPVLETSQ 79 +I +Y P H+ L L+ ++ + ++ ++L + P IP + Sbjct: 1 MIDLYFAPT-PNGHKITLFLEEAELDYRLIKVDLGKGGQFRPEFLRISPNNKIPAIVDHS 59 Query: 80 ----CQLI--YESVIACEYLDDAYPGRKLFPYDPYERAR--QKMLLELFCKVPHLTKECL 131 + + +ES YL + ++ ERA Q + ++ P L + Sbjct: 60 PADGGEPLSLFESGAILLYLAEKTGL--FLSHETRERAATLQWLFWQVGGLGPMLGQNHH 117 Query: 132 VALRCGRECTNLKAALRQEFSNLEEILEY--QNTTFFGGTCISMIDYLLWPWFERLDVYG 189 + + E L +L +N+ + GG S+ D WPW Sbjct: 118 FNHAAPQTIPYAIERYQVETQRLYHVLNKRLENSPWLGGENYSIADIACWPWVNAWTRQR 177 Query: 190 ILDCVSHTPALRLWISAMKWDPTVCALL 217 I ++ PA++ W ++ P L Sbjct: 178 ID--LAMYPAVKNWHERIRSRPATGQAL 203 >5F05-A nrPDB Length = 212 Score = 80.9 bits (198), Expect = 4e-16, Method: Composition-based stats. Identities = 36/207 (17%), Positives = 73/207 (35%), Gaps = 13/207 (6%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRN---KPEWYYTKHPFGHIPVLETSQC 80 ++++ + R L K++ E+VN+NL K E + + +PFG +P Sbjct: 3 LKLHGSVLSTNTQRVLATLYEKEVEFELVNVNLGAGEHKQEPHISLNPFGQVPAAVDGDL 62 Query: 81 QLIYESVIACEYLDDAYPGR-KLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRE 139 + ++ES +Y+ Y + A + E+ + LV + + Sbjct: 63 K-LFESRAISQYVAHQYASKGTQLGAAGNGYATILVWQEVESHQFDPSASKLVWEQVFKP 121 Query: 140 CTNL--KAALRQEFS-NLEEIL-----EYQNTTFFGGTCISMIDYLLWPWFERLDVYGIL 191 L AAL E L ++L + + ++ D P + L Sbjct: 122 VFGLPTDAALVAETEVTLGKVLDVYEARLSQSKYLASDSFTLADLHHLPNIQALLGTPSK 181 Query: 192 DCVSHTPALRLWISAMKWDPTVCALLM 218 P + W++++ P +L Sbjct: 182 KLFDSRPHVSAWVASITGRPAWGKVLA 208 >2PVQ-A nrPDB Length = 201 Score = 80.2 bits (196), Expect = 8e-16, Method: Composition-based stats. Identities = 32/202 (15%), Positives = 66/202 (32%), Gaps = 9/202 (4%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPE----WYYTKHPFGHIPVLETSQ 79 +++Y + S ++L + +E+ ++L+ K Y+ +P G +P LE Sbjct: 1 MKLY-YKVGAASLAPHIILSEAGLPYELEAVDLKAKKTADGGDYFAVNPRGAVPALEVKP 59 Query: 80 CQLIYESVIACEYLDDAYPGRKLFPY-DPYERARQKMLLELFCKVPHLTKECLVALRCGR 138 +I ++ +Y+ D P ERAR + L + Sbjct: 60 GTVITQNAAILQYIGDHSDVAAFKPAYGSIERARLQEALGFCSDLHAAFSGLFAPNLSEE 119 Query: 139 ECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCVSHTP 198 + A + + LE +L ++ G + D + G +S P Sbjct: 120 ARAGVIANINRRLGQLEAML-SDKNAYWLGDDFTQPD--AYASVIIGWGVGQKLDLSAYP 176 Query: 199 ALRLWISAMKWDPTVCALLMDK 220 + P V ++ Sbjct: 177 KALKLRERVLARPNVQKAFKEE 198 >1G6W-A nrPDB Length = 261 Score = 79.4 bits (194), Expect = 1e-15, Method: Composition-based stats. Identities = 35/243 (14%), Positives = 71/243 (29%), Gaps = 46/243 (18%) Query: 20 PEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINL---RNKPEWYYTKHPFGHIPVLE 76 P ++S R P + +VL + + ++ ++ + + +P +P L Sbjct: 17 PLEGYTLFSHRSAPNGFKVAIVLSELGFHYNTIFLDFNLGEHRAPEFVSVNPNARVPALI 76 Query: 77 TS--QCQLIYESVIACEYLDDAY----PGRKLFPYDPYERARQKMLLELFCKVPHLTKEC 130 I+ES +L + Y L+ D ++++ L Sbjct: 77 DHGMDNLSIWESGAILLHLVNKYYKETGNPLLWSDDLADQSQINAWLFFQTSGHAPMIGQ 136 Query: 131 LVALRCGRE-----------------CTNLKAALRQEFSNLEEILEYQNT---------- 163 + R ++ AL + L L+ +N Sbjct: 137 ALHFRYFHSQKIASAVERYTDEVRRVYGVVEMALAERREALVMELDTENAAAYSAGTTPM 196 Query: 164 ---------TFFGGTCISMIDYLLWPWFERLDVYGILDCVSHTPALRLWISAMKWDPTVC 214 + G +++ D PW +D G ++ P + W M P V Sbjct: 197 SQSRFFDYPVWLVGDKLTIADLAFVPWNNVVDRIG-INIKIEFPEVYKWTKHMMRRPAVI 255 Query: 215 ALL 217 L Sbjct: 256 KAL 258 >1PN9-A nrPDB Length = 209 Score = 78.6 bits (192), Expect = 3e-15, Method: Composition-based stats. Identities = 32/194 (16%), Positives = 64/194 (32%), Gaps = 12/194 (6%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP---EWYYTKHPFGHIPVLETSQC 80 + Y + ++ A + + +L + +P IP L Sbjct: 1 MDFYYLPGSAPCRAVQMTAAAVGVELNLKLTDLMKGEHMKPEFLKLNPQHCIPTLV-DNG 59 Query: 81 QLIYESVIACEYLDDAYP-GRKLFPYDPYERAR--QKMLLELFCKVPHLTKECLVALRCG 137 ++ES YL + Y KL+P DP +RA Q++ ++ + Sbjct: 60 FALWESRAIQIYLAEKYGKDDKLYPKDPQKRAVVNQRLYFDMGTLYQRFADYHYPQIFAK 119 Query: 138 RE-CTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCVSH 196 + + ++ L LE Q + G +++ D L +V G + Sbjct: 120 QPANPENEKKMKDAVGFLNTFLEGQE--YAAGNDLTIADLSLAATIATYEVAGFD--FAP 175 Query: 197 TPALRLWISAMKWD 210 P + W + K + Sbjct: 176 YPNVAAWFARCKAN 189 >1V2A-A nrPDB Length = 210 Score = 78.2 bits (191), Expect = 3e-15, Method: Composition-based stats. Identities = 34/207 (16%), Positives = 70/207 (33%), Gaps = 16/207 (7%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRN--KPEWYYTKHPFGHIPVLETSQCQ 81 + Y P L+ K I + N+ + + + +P IP L Sbjct: 1 MDYYYSLISPPCQSAILLAKKLGITLNLKKTNVHDPVERDALTKLNPQHTIPTLV-DNGH 59 Query: 82 LIYESVIACEYLDDAY-PGRKLFPYDPYERAR--QKMLLELFCKVPHLTKECLVALRCGR 138 +++ES YL + Y L+P DP R+ Q++ ++ + + ++ + Sbjct: 60 VVWESYAIVLYLVETYAKDDTLYPKDPKVRSVVNQRLFFDIGTLYKRIIDVIHLVMKKEQ 119 Query: 139 ECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCVSHTP 198 L+ LE+ + + + +++ D L L+ + P Sbjct: 120 PSDEQMEKLKGALDLLEQFVTERA--YAAADHLTVADICLLGTVTALNWLKHD--LEPFP 175 Query: 199 ALRLWISAMKWDPTVCALLMDKSIFQG 225 +R W+ V A + D F Sbjct: 176 HIRAWLER------VRAEMPDYEEFSK 196 >1YQ1-A nrPDB Length = 208 Score = 76.3 bits (186), Expect = 1e-14, Method: Composition-based stats. Identities = 38/207 (18%), Positives = 67/207 (32%), Gaps = 13/207 (6%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQLI 83 ++ F RL+ ++ E V +N P +PVL + Sbjct: 4 YKLTYFFFRGLGEPIRLLFHLAGVQFEEVRMNPDQTWLDIKDSTPMKQLPVLNI-DGFEL 62 Query: 84 YESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECTNL 143 +S YL + P E A + +LF K+ R G+ + Sbjct: 63 PQSGAILRYLARKFG---FAGKTPEEEAWVDAVHDLFKDFLAEFKKFAAERRSGKSAEEV 119 Query: 144 KA--------ALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCVS 195 + A F+ L +LE N+ F G+ I+ D ++ L YG+ D S Sbjct: 120 EKFRSEFFLPARNTYFNILNGLLEKSNSGFLIGSDITFADLVVVDNLLTLKNYGLFD-ES 178 Query: 196 HTPALRLWISAMKWDPTVCALLMDKSI 222 L + P + + + + Sbjct: 179 EFTKLAALREKVNSYPGIKEYIAKRPV 205 >5ZWP-A nrPDB Length = 208 Score = 75.5 bits (184), Expect = 2e-14, Method: Composition-based stats. Identities = 35/192 (18%), Positives = 61/192 (31%), Gaps = 12/192 (6%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP---EWYYTKHPFGHIPVLETSQC 80 + Y + + KA I +NL+ + +P IP L Sbjct: 1 MDFYYLPGSAPCRSVLMTAKALGIELNKKLLNLQAGEHLKPEFLKINPQHTIPTLVDGD- 59 Query: 81 QLIYESVIACEYLDDAYPGR-KLFPYDPYERAR--QKMLLELFCKVPHLTKECLVALRCG 137 ++ES YL + Y LFP P +RA Q++ ++ + Sbjct: 60 FALWESRAIMVYLVEKYGKTDSLFPKCPKKRAVINQRLYFDMGTLYKSFADYYYPQIFAK 119 Query: 138 RECTN-LKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCVSH 196 L + F L L+ + G +++ D L +V D S Sbjct: 120 APADPELFKKIETAFDFLNTFLKGHE--YAAGDSLTVADLALLASVSTFEV-ASFDI-SK 175 Query: 197 TPALRLWISAMK 208 P + W + +K Sbjct: 176 YPNVAKWYANLK 187 >5F0G-A nrPDB Length = 215 Score = 75.5 bits (184), Expect = 2e-14, Method: Composition-based stats. Identities = 43/214 (20%), Positives = 72/214 (33%), Gaps = 17/214 (7%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEW---YYTKHPFGHIPVLETSQC 80 + Y M +V KA + +N + + +P IP L Sbjct: 1 MDFYYMPGGGGCRTVIMVAKALGLELNKKLLNTMEGEQLKPEFVKLNPQHTIPTLV-DNG 59 Query: 81 QLIYESVIACEYLDDAYP-GRKLFPYDPYERAR--QKMLLELFCKVPHLTKECLVALRCG 137 I+ES YL + Y L P DP +RA Q++ ++ K R G Sbjct: 60 FSIWESRAIAVYLVEKYGKDDYLLPNDPKKRAVINQRLYFDMGTLYESFAKYYYPLFRTG 119 Query: 138 RECTNLK-AALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCVSH 196 + ++ + F L+ LE Q + G +++ D + +V D S Sbjct: 120 KPGSDEDLKRIETAFGFLDTFLEGQE--YVAGDQLTVADIAILSTVSTFEV-SEFDF-SK 175 Query: 197 TPALRLWISAMK-----WDPTVCALLMDKSIFQG 225 + W K WD L+ K++F Sbjct: 176 YSNVSRWYDNAKKVTPGWDENWEGLMAMKALFDA 209 >4MPF-A nrPDB Length = 266 Score = 75.5 bits (184), Expect = 2e-14, Method: Composition-based stats. Identities = 29/193 (15%), Positives = 66/193 (34%), Gaps = 15/193 (7%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINL---RNKPEWYYTKHPFGHIPVLETSQC 80 + ++ S + K I E+ ++L ++K + + + G +P L+ Sbjct: 25 LELFLDLVSQPSRAVYIFAKKNGIPLELRTVDLVKGQHKSKEFLQINSLGKLPTLKDGD- 83 Query: 81 QLIYESVIACEYLDDAYPGRK-LFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRE 139 ++ ES YL Y +P D RAR L T + ++ Sbjct: 84 FILTESSAILIYLSCKYQTPDHWYPSDLQARARVHEYLGWHADCIRGTFGIPLWVQVLGP 143 Query: 140 CTNLK---AALRQEFSNLEEILEY------QNTTFFGGTCISMIDYLLWPWFERLDVYGI 190 ++ + + + +++ L++ + F G +++ D + + G Sbjct: 144 LIGVQVPKEKVERNRTAMDQALQWLEDKFLGDRPFLAGQQVTLADLMALEELMQPVALG- 202 Query: 191 LDCVSHTPALRLW 203 + P L W Sbjct: 203 YELFEGRPRLAAW 215 >5Y7I-A nrPDB Length = 261 Score = 75.5 bits (184), Expect = 2e-14, Method: Composition-based stats. Identities = 36/223 (16%), Positives = 70/223 (31%), Gaps = 29/223 (13%) Query: 32 CPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQLIYESVIACE 91 CP+ R +VL K ++ V +++R KP P G P L + + E Sbjct: 46 CPFCQRLFMVLWLKGVKFTVTTVDMRKKPAELKDLAP-GTNPPFLLYNGTLKTDFIKIEE 104 Query: 92 YLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECTNLKAALRQEF 151 +L+ + P + E F + + ++ + L +EF Sbjct: 105 FLEQTLAPPRYPHLSPVNK-------ESFDVGADIFAKFSAFIKNSPNNPLQEKNLLREF 157 Query: 152 SNLEEILEY----------------QNTTFFGGTCISMIDYLLWPWFERLDV----YGIL 191 L++ L N F G +++ D L P + V Y Sbjct: 158 KRLDDYLNSPLPEEIDHNSVETITVSNRKFLDGDRLTLADCNLLPKLHVIRVAAKKYCNF 217 Query: 192 DCVSHTPALRLWISAMKWDPTVCALLM-DKSIFQGFLNLYFQN 233 + H + ++ D I + +L++ + Sbjct: 218 EIPDHFTGVWRYLKNADERDEFKQTCPADIEIEKAYLSVANKR 260 >3MAK-A nrPDB Length = 209 Score = 73.2 bits (178), Expect = 9e-14, Method: Composition-based stats. Identities = 34/214 (15%), Positives = 64/214 (29%), Gaps = 13/214 (6%) Query: 23 LIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP---EWYYTKHPFGHIPVLETSQ 79 ++ Y + + KA + +NL+ + +P IP L Sbjct: 1 MVDFYYLPGSSPCRSVIMTAKAVGVELNKKLLNLQAGEHLKPEFLKINPQHTIPTLV-DN 59 Query: 80 CQLIYESVIACEYLDDAYPGR-KLFPYDPYERAR--QKMLLELFCKVPHLTKECLVALRC 136 ++ES YL + Y L+P P +RA Q++ ++ + Sbjct: 60 GFALWESRAIQVYLVEKYGKTDSLYPKCPKKRAVINQRLYFDMGTLYQSFANYYYPQVFA 119 Query: 137 GRECTNLK-AALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCVS 195 + F L LE Q+ + G +++ D L +V +S Sbjct: 120 KAPADPEAFKKIEAAFEFLNTFLEGQD--YAAGDSLTVADIALVATVSTFEVAKFE--IS 175 Query: 196 HTPALRLWISAMKW-DPTVCALLMDKSIFQGFLN 228 + W K P F+ + Sbjct: 176 KYANVNRWYENAKKVTPGWEENWAGCLEFKKYFE 209 >5D73-A nrPDB Length = 208 Score = 72.1 bits (175), Expect = 2e-13, Method: Composition-based stats. Identities = 43/202 (21%), Positives = 79/202 (39%), Gaps = 12/202 (5%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQLI 83 ++ + RLVL + I+ IN + P H FG +P L Q++ Sbjct: 3 YKLTYFPIRGLAEPIRLVLVDQGIKFTDDRINASDWPSMKSHFH-FGQLPCLYDGDHQIV 61 Query: 84 YESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECTNL 143 +S +L + L + E M E + + + + + + Sbjct: 62 -QSGAILRHLARKH---NLNGGNELETTHIDMFCEGVRDLHTKYTKMIYQAYDTEKDSYI 117 Query: 144 KAALRQEFSNLEEILEYQN--TTFFGGTCISMIDYLLWPWFERLDVYGILD--CVSHTPA 199 K L E + E++L ++ F G IS +D++L FE LD++ ILD C+ P Sbjct: 118 KDILPVELAKFEKLLATRDDGKNFILGEKISYVDFVL---FEELDIHQILDPHCLDKFPL 174 Query: 200 LRLWISAMKWDPTVCALLMDKS 221 L+ + M+ P + ++ Sbjct: 175 LKAYHQRMEDRPGLKEYCKQRN 196 >1VF1-A nrPDB Length = 229 Score = 70.1 bits (170), Expect = 8e-13, Method: Composition-based stats. Identities = 36/190 (18%), Positives = 67/190 (35%), Gaps = 10/190 (5%) Query: 38 TRLVLKAKDIRHEVVNINLRNKPEWYYT--KHPFGHIPVLETSQCQLIYESVIACEYLDD 95 R +L A + E V + R + E F +P++E +L+ ++ Y+ Sbjct: 19 IRWLLAAAGVEFEEVFLETREQYEKLLQSGILMFQQVPMVEIDGMKLV-QTRAILNYIAG 77 Query: 96 AYPGRKLFPYDPYERARQKMLLELFCKVPHLTKEC---LVALRCGRECTNLKAALRQEFS 152 Y L+ D ERA M + + + + ++ A + F Sbjct: 78 KY---NLYGKDLKERALIDMYVGGTDDLMGFLLSFPFLSAEDKVKQCAFVVEKATSRYFP 134 Query: 153 NLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCVSHTPALRLWISAMKWDPT 212 E++L+ F G +S D L ++ D +S P L+ + + PT Sbjct: 135 AYEKVLKDHGQDFLVGNRLSWADIHLLEAILMVEE-KKSDALSGFPLLQAFKKRISSIPT 193 Query: 213 VCALLMDKSI 222 + L S Sbjct: 194 IKKFLAPGSK 203 >3GH6-A nrPDB Length = 210 Score = 69.8 bits (169), Expect = 1e-12, Method: Composition-based stats. Identities = 38/214 (17%), Positives = 64/214 (29%), Gaps = 14/214 (6%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNIN----LRNKPEWYYTKHPFGHIPVLETSQ 79 + +Y + KA + + I Y +P IP L Sbjct: 1 MDLYYRPGSAPCRSVLMTAKALGVEFDKKTIINTRAREQFTPEYLKINPQHTIPTLHDH- 59 Query: 80 CQLIYESVIACEYLDDAYP-GRKLFPYDPYERA--RQKMLLELFCKVPHLTKECLVALR- 135 ++ES YL + Y KLFP D ++A Q++ ++ ++ + Sbjct: 60 GFALWESRAIMVYLVEKYGKDDKLFPKDVQKQALINQRLYFDMGTLYKSFSEYYYPQIFL 119 Query: 136 CGRECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCVS 195 + F L LE Q T+ G S+ D DV G D Sbjct: 120 KKPANEENYKKIEVAFEFLNTFLEGQ--TYSAGGDYSLADIAFLATVSTFDVAG-FDFKR 176 Query: 196 HTPALRLWISAMKW-DPTVCALLMDKSIFQGFLN 228 + + W K P F+ + + Sbjct: 177 YA-NVARWYENAKKLTPGWEENWAGCQEFRKYFD 209 >4Q5F-A nrPDB Length = 218 Score = 69.4 bits (168), Expect = 1e-12, Method: Composition-based stats. Identities = 36/208 (17%), Positives = 72/208 (34%), Gaps = 17/208 (8%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEW--YYTKHPFGHIPVLETSQCQ 81 ++ RL+ ++ E N + +W K PFG +P+LE + Sbjct: 16 YKLTYFDIRGLGEGARLIFHQAGVKFED---NRLKREDWPALKPKTPFGQLPLLEV-DGE 71 Query: 82 LIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECT 141 ++ +S YL + L P E A+ + + F + C L E Sbjct: 72 VLAQSAAIYRYLGRQFG---LAGKTPMEEAQVDSIFDQFKDFMAELRPCFRVLAGFEEGD 128 Query: 142 NLK-------AALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCV 194 K A + LE+ L + + G ++ D ++ + I D + Sbjct: 129 KEKVLKEVAVPARDKHLPLLEKFLAKSGSEYMVGKSVTWADLVITDSLASWESL-IPDFL 187 Query: 195 SHTPALRLWISAMKWDPTVCALLMDKSI 222 S L+ +I ++ P + + ++ Sbjct: 188 SGHLQLKKYIEHVRELPNIKKWIAERPK 215 >5F8B-A nrPDB Length = 244 Score = 69.4 bits (168), Expect = 1e-12, Method: Composition-based stats. Identities = 28/197 (14%), Positives = 56/197 (28%), Gaps = 15/197 (7%) Query: 46 DIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPY 105 + ++ + + + G +P + + ++E + Y+ L Sbjct: 27 GLDLDIRET---PRTPDHLSISKLGKVPAFQGADSFKLFECMAIALYITSQNEQTTLLGK 83 Query: 106 DPYERARQKMLLELFCKVPHLTKECLVALRCG------RECTNLKAALRQEFSNLEEILE 159 D E A + F + + + G + ++ +EE L Sbjct: 84 DKKEYAEIIKWMSFFNTEIVILMTQQLLPQLGVIPYDRDQVEFFANMTQRSVDVVEEYL- 142 Query: 160 YQNTTFFGGTCISMIDYLLWPWFER-LDVYGILDCVSHTPALRLWISAMKWDPTVCALLM 218 Q+ TF G +S+ D + P + W + P A+ Sbjct: 143 -QDRTFLVGDQLSLADLFCAGNISLGFQFFYGKAWRQQNPNVSRWYEMVCHQPIYAAV-- 199 Query: 219 DKSIFQGFLNLYFQNNP 235 FQ NNP Sbjct: 200 -TDKFQLLDEPKLTNNP 215 >2VCV-A nrPDB Length = 222 Score = 69.4 bits (168), Expect = 2e-12, Method: Composition-based stats. Identities = 42/210 (20%), Positives = 74/210 (35%), Gaps = 20/210 (9%) Query: 22 GLIRIYSMRFCPYSHRTRLVLKAKDIRHEVV----NINLRNKPEWYYTKHPFGHIPVLET 77 G +++ R +L A + E +L F +P++E Sbjct: 3 GKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLM--FQQVPMVEI 60 Query: 78 SQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCG 137 +L+ ++ Y+ Y L+ D ERA M E + L + L+ C Sbjct: 61 DGMKLV-QTRAILNYIASKY---NLYGKDIKERALIDMYTE---GMADLNEMILLLPLCR 113 Query: 138 RECTNLKAALRQE------FSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGIL 191 E + K AL +E F E++L+ + G +S D L ++ Sbjct: 114 PEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEEL-DS 172 Query: 192 DCVSHTPALRLWISAMKWDPTVCALLMDKS 221 +S+ P L+ + + PTV L S Sbjct: 173 SLISNFPLLKALKTRISNLPTVKKFLQPGS 202 >1N2A-A nrPDB Length = 201 Score = 69.0 bits (167), Expect = 2e-12, Method: Composition-based stats. Identities = 32/186 (17%), Positives = 66/186 (35%), Gaps = 14/186 (7%) Query: 40 LVLKAKDIRHEVVNINLRNKP----EWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDD 95 + L+ +V+++L K + Y+ +P G +P L L+ E V +YL D Sbjct: 16 ITLRESGKDFTLVSVDLMKKRLENGDDYFAVNPKGQVPALLLDDGTLLTEGVAIMQYLAD 75 Query: 96 AYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALR----CGRECTNLKAALRQEF 151 + P R+L P + +E + + L ++A L ++ Sbjct: 76 SVPDRQLLA--PVNSISRYKTIEWLNYIATELHKGFTPLFRPDTPEEYKPTVRAQLEKKL 133 Query: 152 SNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCVSHTPALRLWISAMKWDP 211 + E L+ + + G ++ D L+ + + + ++ M P Sbjct: 134 QYVNEALK--DEHWICGQRFTIADAYLFTVLRWAYAVKLN--LEGLEHIAAFMQRMAERP 189 Query: 212 TVCALL 217 V L Sbjct: 190 EVQDAL 195 >3I6A-A nrPDB Length = 222 Score = 67.8 bits (164), Expect = 4e-12, Method: Composition-based stats. Identities = 42/210 (20%), Positives = 75/210 (35%), Gaps = 20/210 (9%) Query: 22 GLIRIYSMRFCPYSHRTRLVLKAKDIRHEVV----NINLRNKPEWYYTKHPFGHIPVLET 77 +++ TR +L A + E +L Y F +P++E Sbjct: 3 EKPKLHYFNGRGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLM--FQQVPMVEI 60 Query: 78 SQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCG 137 +L+ ++ Y+ Y L+ D ERA M +E + L + ++ C Sbjct: 61 DGMKLV-QTRAILNYIASKY---NLYGKDIKERALIDMYIE---GIADLGEMIIMLPFCP 113 Query: 138 RECTNLKAALRQE------FSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGIL 191 E + K AL +E F E++L+ + G +S D L ++ Sbjct: 114 PEEKDAKLALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEEL-DS 172 Query: 192 DCVSHTPALRLWISAMKWDPTVCALLMDKS 221 +S P L+ + + PTV L S Sbjct: 173 SLISSFPLLKALKTRISNLPTVKKFLQPGS 202 >1F3B-A nrPDB Length = 222 Score = 67.4 bits (163), Expect = 6e-12, Method: Composition-based stats. Identities = 35/193 (18%), Positives = 67/193 (34%), Gaps = 16/193 (8%) Query: 38 TRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFG-----HIPVLETSQCQLIYESVIACEY 92 R +L A + E I PE G +P++E + + ++ Y Sbjct: 18 IRWLLAAAGVEFEEKFI---QSPEDLEKLKKDGNLMFDQVPMVEIDGMK-LAQTRAILNY 73 Query: 93 LDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECTNLKAALRQE-- 150 + Y L+ D ERA M E + + + ++ RE A R + Sbjct: 74 IATKY---DLYGKDMKERALIDMYSEGILDLTEMIGQLVLCPPDQREAKTALAKDRTKNR 130 Query: 151 -FSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCVSHTPALRLWISAMKW 209 E++L+ + G ++ +D L ++ + ++ P L+ + S + Sbjct: 131 YLPAFEKVLKSHGQDYLVGNRLTRVDIHLLEVLLYVEEF-DASLLTPFPLLKAFKSRISS 189 Query: 210 DPTVCALLMDKSI 222 P V L S Sbjct: 190 LPNVKKFLQPGSQ 202 >2VCT-A nrPDB Length = 222 Score = 67.4 bits (163), Expect = 6e-12, Method: Composition-based stats. Identities = 41/207 (19%), Positives = 73/207 (35%), Gaps = 20/207 (9%) Query: 25 RIYSMRFCPYSHRTRLVLKAKDIRHEVV----NINLRNKPEWYYTKHPFGHIPVLETSQC 80 +++ R +L A + E +L Y F +P++E Sbjct: 6 KLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLM--FQQVPMVEIDGM 63 Query: 81 QLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGREC 140 +L+ ++ Y+ Y L+ D E+A M +E + L + L+ E Sbjct: 64 KLV-QTRAILNYIASKY---NLYGKDIKEKALIDMYIE---GIADLGEMILLLPFTQPEE 116 Query: 141 TNLKAALRQE------FSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCV 194 + K AL QE F E++L+ + G +S D L ++ + Sbjct: 117 QDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEEL-DSSLI 175 Query: 195 SHTPALRLWISAMKWDPTVCALLMDKS 221 S P L+ + + PTV L S Sbjct: 176 SSFPLLKALKTRISNLPTVKKFLQPGS 202 >2D2Z-A nrPDB Length = 261 Score = 67.1 bits (162), Expect = 6e-12, Method: Composition-based stats. Identities = 35/216 (16%), Positives = 65/216 (30%), Gaps = 27/216 (12%) Query: 32 CPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQLIYESVIACE 91 CP+S R ++L K + V ++L+ KP P G P T ++ + E Sbjct: 35 CPFSQRLFMILWLKGVVFSVTTVDLKRKPADLQNLAP-GTHPPFITFNSEVKTDVNKIEE 93 Query: 92 YLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECTNLKAALRQEF 151 +L++ K P +++F K K L+ L + Sbjct: 94 FLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRP-----EANEALERGLLKTL 148 Query: 152 SNLEEIL----------------EYQNTTFFGGTCISMIDYLLWPWFE----RLDVYGIL 191 L+E L ++ F G +++ D L P Y Sbjct: 149 QKLDEYLNSPLPDEIDENSMEDIKFSTRKFLDGNEMTLADCNLLPKLHIVKVVAKKYRNF 208 Query: 192 DCVSHTPALRLWISAMKWDPTVCALLM-DKSIFQGF 226 D + +++ DK + + Sbjct: 209 DIPKEMTGIWRYLTNAYSRDEFTNTCPSDKEVEIAY 244 >1PL2-A nrPDB Length = 222 Score = 67.1 bits (162), Expect = 6e-12, Method: Composition-based stats. Identities = 44/207 (21%), Positives = 74/207 (35%), Gaps = 20/207 (9%) Query: 25 RIYSMRFCPYSHRTRLVLKAKDIRHEVV----NINLRNKPEWYYTKHPFGHIPVLETSQC 80 +++ TR +L A + E +L Y F +P++E Sbjct: 6 KLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLM--FQQVPMVEIDGM 63 Query: 81 QLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGREC 140 +L+ E Y+ Y L+ D ERA M +E + L + L+ C E Sbjct: 64 KLVQE-RAILNYIASKY---NLYGKDIKERALIDMYIE---GIADLGEMILLLPVCPPEE 116 Query: 141 TNLKAALRQE------FSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCV 194 + K AL +E F E++L+ + G +S D L ++ + Sbjct: 117 KDAKLALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEEL-DSSLI 175 Query: 195 SHTPALRLWISAMKWDPTVCALLMDKS 221 S P L+ + + PTV L S Sbjct: 176 SSFPLLKALKTRISNLPTVKKFLQPGS 202 >2C3Q-A nrPDB Length = 247 Score = 66.3 bits (160), Expect = 1e-11, Method: Composition-based stats. Identities = 38/200 (19%), Positives = 62/200 (31%), Gaps = 16/200 (8%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNK---PEWYYTKHPFGHIPVLETSQC 80 + +Y + K DI E+ ++L + + +P +P L+ Sbjct: 10 LELYLDLLSQPCRAVYIFAKKNDIPFELRIVDLIKGQHLSDAFAQVNPLKKVPALKDGD- 68 Query: 81 QLIYESVIACEYLDDAYPGRKL-FPYDPYERARQKMLLELF------CKVPHLTKECLVA 133 + ESV YL Y +P D RAR L + L + + Sbjct: 69 FTLTESVAILLYLTRKYKVPDYWYPQDLQARARVDEYLAWQHTTLRRSCLRALWHKVMFP 128 Query: 134 LRCGRECTNLKAALR-QEFSNLEEILEY---QNTTFFGGTCISMIDYLLWPWFERLDVYG 189 + G + A E ++LE QN F G IS+ D + V Sbjct: 129 VFLGEPVSPQTLAATLAELDVTLQLLEDKFLQNKAFLTGPHISLADLVAITELMH-PVGA 187 Query: 190 ILDCVSHTPALRLWISAMKW 209 P L W ++ Sbjct: 188 GCQVFEGRPKLATWRQRVEA 207 >2R5G-A nrPDB Length = 247 Score = 65.1 bits (157), Expect = 2e-11, Method: Composition-based stats. Identities = 37/226 (16%), Positives = 71/226 (31%), Gaps = 31/226 (13%) Query: 32 CPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQLIYESVIACE 91 CP+ R ++L K ++ V +++ KPE P G P +L + + E Sbjct: 30 CPFCQRLFMILWLKGVKFNVTTVDMTRKPEELKDLAP-GTNPPFLVYNKELKTDFIKIEE 88 Query: 92 YLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALR--CGRECTNLKAALRQ 149 +L+ + P + E F +L + ++ N + +L + Sbjct: 89 FLEQTLAPPRYPHLSPKYK-------ESFDVGCNLFAKFSAYIKNTQKEANKNFEKSLLK 141 Query: 150 EFSNLEEILEY----------------QNTTFFGGTCISMIDYLLWPWF----ERLDVYG 189 EF L++ L F G +++ D L P Y Sbjct: 142 EFKRLDDYLNTPLLDEIDPDSAEEPPVSRRLFLDGDQLTLADCSLLPKLNIIKVAAKKYR 201 Query: 190 ILDCVSHTPALRLWISAMKWDPTVCALLM-DKSIFQGFLNLYFQNN 234 D + + ++ DK I + N+ Q + Sbjct: 202 DFDIPAEFSGVWRYLHNAYAREEFTHTCPEDKEIENTYANVAKQKS 247 >3FY7-A nrPDB Length = 250 Score = 65.1 bits (157), Expect = 3e-11, Method: Composition-based stats. Identities = 32/209 (15%), Positives = 67/209 (32%), Gaps = 15/209 (7%) Query: 32 CPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQLIYESVIACE 91 CP R +VL K + + ++ R P+ P +P+L +++ + Sbjct: 42 CPSCQRLFMVLLLKGVPFTLTTVDTRRSPDVLKDFAPGSQLPILLYDSD-AKTDTLQIED 100 Query: 92 YLDDAYPGRKLFPYDPYER----ARQKMLLEL--FCKVPHLTKECLVALRCGRECTNLKA 145 +L++ P R A + + F K P ++ + + R L + Sbjct: 101 FLEETLGPPDFPSLAPRYRESNTAGNDVFHKFSAFIKNPVPAQDEALYQQLLRALARLDS 160 Query: 146 ALRQEFSNL---EEILEYQNTTFFGGTCISMIDYLLWPWFERLD----VYGILDCVSHTP 198 LR + E L F G +++ D L P +D + + Sbjct: 161 YLRAPLEHELAGEPQLRESRRRFLDGDRLTLADCSLLPKLHIVDTVCAHFRQAPIPAELR 220 Query: 199 ALRLWISAMKWDPTVCALLM-DKSIFQGF 226 +R ++ + + I + Sbjct: 221 GVRRYLDSAMQEKEFKYTCPHSAEILAAY 249 >1GUL-A nrPDB Length = 222 Score = 65.1 bits (157), Expect = 3e-11, Method: Composition-based stats. Identities = 42/192 (21%), Positives = 74/192 (38%), Gaps = 14/192 (7%) Query: 38 TRLVLKAKDIRHEVVNINLRNKPEWYYTKHP----FGHIPVLETSQCQLIYESVIACEYL 93 R VL A + + L K + Y + F +P++E +L+ ++ Y+ Sbjct: 19 VRWVLAAAGVEFD--EEFLETKEQLYKLQDGNHLLFQQVPMVEIDGMKLV-QTRSILHYI 75 Query: 94 DDAYPGRKLFPYDPYERARQKMLLE--LFCKVPHLTKECLVALRCGRECTN-LKAALRQE 150 D + LF + ER M +E L + L +E N + A+ + Sbjct: 76 ADKH---NLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKEVVNMAQKAIIRY 132 Query: 151 FSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCVSHTPALRLWISAMKWD 210 F E+IL +F G +S+ D +L L+ I + +S P L+ + + Sbjct: 133 FPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEE-KIPNILSAFPFLQEYTVKLSNI 191 Query: 211 PTVCALLMDKSI 222 PT+ L S Sbjct: 192 PTIKRFLEPGSK 203 >5LCZ-A nrPDB Length = 222 Score = 64.8 bits (156), Expect = 3e-11, Method: Composition-based stats. Identities = 36/208 (17%), Positives = 72/208 (34%), Gaps = 14/208 (6%) Query: 22 GLIRIYSMRFCPYSHRTRLVLKAKDIRHEVV----NINLRNKPEWYYTKHPFGHIPVLET 77 +++ TR +L A + E +L Y F +P++E Sbjct: 3 EKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLM--FQQVPMVEI 60 Query: 78 SQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCG 137 +L+ ++ Y+ Y L+ D ERA M E + + + ++ Sbjct: 61 DGMKLV-QTRAILNYIASKY---NLYGKDMKERALIDMYSEGILDLTEMIIQLVICPPDQ 116 Query: 138 RECTNLKAALRQE---FSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCV 194 RE A R + E++L+ + G ++ +D L ++ + + Sbjct: 117 REAKTALAKDRTKNRYLPAFEKVLKSHGQDYLVGNRLTRVDIHLLELLLYVEEF-DASLL 175 Query: 195 SHTPALRLWISAMKWDPTVCALLMDKSI 222 + P L+ + S + P V L S Sbjct: 176 TSFPLLKAFKSRISSLPNVKKFLQPGSQ 203 >3BBY-A nrPDB Length = 215 Score = 64.8 bits (156), Expect = 3e-11, Method: Composition-based stats. Identities = 34/163 (20%), Positives = 61/163 (37%), Gaps = 13/163 (7%) Query: 28 SMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGH---IPVLETSQCQLIY 84 + F PY + L+ K + + I+L + T +G +P+L+ + + Sbjct: 13 AHFFSPYVLSAWVALQEKGLSFHIKTIDLDSGEHLQPTWQGYGQTRRVPLLQIDDFE-LS 71 Query: 85 ESVIACEYLDDAYPGR---KLFPYDPYERARQKMLLELFCKVPHLTKE------CLVALR 135 ES EYL+D + +++P D RAR + + +E + Sbjct: 72 ESSAIAEYLEDRFAPPTWERIYPLDLENRARARQIQAWLRSDLMPIREERPTDVVFAGAK 131 Query: 136 CGRECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLL 178 KA+ + F+ E +L FG CI+ D L Sbjct: 132 KAPLTAEGKASAEKLFAMAEHLLVLGQPNLFGEWCIADTDLAL 174 >1TU7-A nrPDB Length = 208 Score = 64.4 bits (155), Expect = 4e-11, Method: Composition-based stats. Identities = 44/205 (21%), Positives = 75/205 (36%), Gaps = 18/205 (8%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHP---FGHIPVLETSQC 80 ++ + RL L +DI+ I+ R + + + FG +P L Sbjct: 3 YKLTYFSIRGLAEPIRLFLVDQDIKF----IDDRIAKDDFSSIKSQFQFGQLPCLYDGDQ 58 Query: 81 QLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGREC 140 Q++ +S +L Y L + E M E + + + Sbjct: 59 QIV-QSGAILRHLARKY---NLNGENEMETTYIDMFCEGVRDLHVKYTRMIYMAYETEKD 114 Query: 141 TNLKAALRQEFSNLEEILEYQN--TTFFGGTCISMIDYLLWPWFERLDVYGILD--CVSH 196 +K+ L E + E++L + G IS DY L FE LDV+ ILD C+ Sbjct: 115 PYIKSILPGELAKFEKLLATRGNGRNLILGDKISYADYAL---FEELDVHQILDPHCLDK 171 Query: 197 TPALRLWISAMKWDPTVCALLMDKS 221 P L+++ MK P + + Sbjct: 172 FPLLKVFHQRMKDRPKLKEYCEKRD 196 >4Q5R-A nrPDB Length = 204 Score = 63.6 bits (153), Expect = 7e-11, Method: Composition-based stats. Identities = 34/202 (16%), Positives = 65/202 (32%), Gaps = 15/202 (7%) Query: 27 YSMRFCPY-----SHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQ 81 Y + +CP R L K E + P + PFG PVLE + Sbjct: 5 YKLTYCPVKALGEPIRFLLSYGEK--DFEDYRFQEGDWPNLKPSM-PFGKTPVLEI-DGK 60 Query: 82 LIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKE---CLVALRCGR 138 ++SV YL + L D +E M+++ + Sbjct: 61 QTHQSVAISRYLGKQFG---LSGKDDWENLEIDMIVDTISDFRAAIANYHYDADENSKQK 117 Query: 139 ECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCVSHTP 198 + LK ++ + + N + ++ D+ + L+ D V++ P Sbjct: 118 KWDPLKKETIPYYTKKFDEVVKANGGYLAAGKLTWADFYFVAILDYLNHMAKEDLVANQP 177 Query: 199 ALRLWISAMKWDPTVCALLMDK 220 L+ + P + A + + Sbjct: 178 NLKALREKVLGLPAIKAWVAKR 199 >1B48-A nrPDB Length = 221 Score = 63.6 bits (153), Expect = 7e-11, Method: Composition-based stats. Identities = 39/206 (18%), Positives = 68/206 (33%), Gaps = 16/206 (7%) Query: 25 RIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHP-----FGHIPVLETSQ 79 ++Y R +L A + E E Y FG +P++E Sbjct: 5 KLYYFNGRGRMESIRWLLAAAGVEFE---EEFLETREQYEKMQKDGHLLFGQVPLVEI-D 60 Query: 80 CQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKEC-LVALRCGR 138 ++ ++ YL Y L+ D ER R M + + + + Sbjct: 61 GMMLTQTRAILSYLAAKY---NLYGKDLKERVRIDMYADGTQDLMMMIAVAPFKTPKEKE 117 Query: 139 ECTNL--KAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCVSH 196 E +L A + F E+IL+ F G +S D L ++ +S Sbjct: 118 ESYDLILSRAKTRYFPVFEKILKDHGEAFLVGNQLSWADIQLLEAILMVEEL-SAPVLSD 176 Query: 197 TPALRLWISAMKWDPTVCALLMDKSI 222 P L+ + + + PT+ L S Sbjct: 177 FPLLQAFKTRISNIPTIKKFLQPGSQ 202 >4K0G-A nrPDB Length = 251 Score = 61.3 bits (147), Expect = 3e-10, Method: Composition-based stats. Identities = 34/212 (16%), Positives = 62/212 (29%), Gaps = 26/212 (12%) Query: 32 CPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQLIYESVIACE 91 P+S R +VL K + V ++ + + E P G +P L ++ ++ E Sbjct: 34 SPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFL-LYGTEVHTDTNKIEE 92 Query: 92 YLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECTNLKAALRQEF 151 +L+ + L++F K K AL NL+ L + Sbjct: 93 FLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPAL-----NDNLEKGLLKAL 147 Query: 152 SNLEEILEY----------------QNTTFFGGTCISMIDYLLWPWFERLDV----YGIL 191 L+ L F G +++ D L P + V Y Sbjct: 148 KVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYRGF 207 Query: 192 DCVSHTPALRLWISAMKWDPTVCALLMDKSIF 223 + ++S + D Sbjct: 208 TIPEAFRGVHRYLSNAYAREEFASTCPDDEEI 239 >1EV4-A nrPDB Length = 221 Score = 61.3 bits (147), Expect = 4e-10, Method: Composition-based stats. Identities = 32/193 (16%), Positives = 65/193 (33%), Gaps = 16/193 (8%) Query: 38 TRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFG-----HIPVLETSQCQLIYESVIACEY 92 R +L A + + I PE G +P++E + + ++ Y Sbjct: 18 IRFLLAAAGVEFDEKFI---QSPEDLEKLKKDGNLMFDQVPMVEIDGMK-LAQTRAILNY 73 Query: 93 LDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLV-ALRCGRECTNLKAALRQE- 150 + Y L+ D ERA M E + + + ++ T L + Sbjct: 74 IATKY---DLYGKDMKERALIDMYSEGILDLTEMIMQLVICPPDQKEAKTALAKDRTKNR 130 Query: 151 -FSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCVSHTPALRLWISAMKW 209 E++L+ + G ++ +D L ++ + ++ P L+ + S + Sbjct: 131 YLPAFEKVLKSHGQDYLVGNKLTRVDIHLLELLLYVEEF-DASLLTSFPLLKAFKSRISS 189 Query: 210 DPTVCALLMDKSI 222 P V L S Sbjct: 190 LPNVKKFLQPGSQ 202 >1G7O-A nrPDB Length = 215 Score = 60.1 bits (144), Expect = 7e-10, Method: Composition-based stats. Identities = 29/193 (15%), Positives = 59/193 (30%), Gaps = 22/193 (11%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQLI 83 +++Y CPY + R++ K+I E+ + L + E +P+L+ + + Sbjct: 1 MKLYIYDHCPYCLKARMIFGLKNIPVELH-VLLNDDAETPTRMVGQKQVPILQKDDSRYM 59 Query: 84 YESVIACEYLDDAYPGRKLFPY-----DPYERARQ---------KMLLELFCKVPHLTKE 129 ES+ Y+D L + + R + F + Sbjct: 60 PESMDIVHYVDKLDGKPLLTGKRSPAIEEWLRKVNGYANKLLLPRFAKSAFDEFSTPAAR 119 Query: 130 CLVALRCGRECTNLKAALRQEFSNLEEI---LEYQN----TTFFGGTCISMIDYLLWPWF 182 + N L ++ I L + +S D L+P Sbjct: 120 KYFVDKKEASAGNFADLLAHSDGLIKNISDDLRALDKLIVKPNAVNGELSEDDIQLFPLL 179 Query: 183 ERLDVYGILDCVS 195 L + ++ S Sbjct: 180 RNLTLVAGINWPS 192 >2AAW-A nrPDB Length = 222 Score = 59.4 bits (142), Expect = 1e-09, Method: Composition-based stats. Identities = 29/214 (13%), Positives = 67/214 (31%), Gaps = 21/214 (9%) Query: 21 EGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKH-------PFGHIP 73 I +Y + RL+ I + + N + K+ PF +P Sbjct: 13 GDNIVLYYFDARGKAELIRLIFAYLGIEYTDKRFGV-NGDAFVEFKNFKKEKDTPFEQVP 71 Query: 74 VLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVA 133 +L+ ++ +S YL Y + M+ + + Sbjct: 72 ILQIGD-LILAQSQAIVRYLSKKY---NICGESELNEFYADMIFCGVQDIHYKFNN--TN 125 Query: 134 LRCGRECTNLKAALRQEFSNLEEILE------YQNTTFFGGTCISMIDYLLWPWFERLDV 187 L E T L L + E++L+ + +F G ++ D ++ ++ ++ Sbjct: 126 LFKQNETTFLNEDLPKWSGYFEKLLKKNHTNNNNDKYYFVGNNLTYADLAVFNLYDDIET 185 Query: 188 YGILDCVSHTPALRLWISAMKWDPTVCALLMDKS 221 + P L+ + P + + ++ Sbjct: 186 KYPSSLKN-FPLLKAHNEFISNLPNIKNYITNRK 218 >1ZL9-A nrPDB Length = 207 Score = 58.6 bits (140), Expect = 2e-09, Method: Composition-based stats. Identities = 29/162 (17%), Positives = 53/162 (32%), Gaps = 13/162 (8%) Query: 68 PFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLT 127 PFG +P LE + + +S +L + KL +E A+ L + + Sbjct: 49 PFGQLPFLEV-DGKKLAQSHAIARFLAREF---KLNGKTAWEEAQVNSLADQYKDYSSEA 104 Query: 128 KECL---VALRCGRECTNLKAALRQEFSN----LEEILEYQNTTFFGGTCISMIDYLLWP 180 + + G T K F L L+ + F G ++ ID + Sbjct: 105 RPYFYAVMGFGPGDVETLKKDIFLPAFEKFYGFLVNFLKASGSGFLVGDSLTWIDLAIAQ 164 Query: 181 WFERLDVYGILDCVSHTPALRLWISAMKWDPTVCALLMDKSI 222 L G S P L+ ++ P + + + + Sbjct: 165 HSADLIAKGGD--FSKFPELKAHAEKIQAIPQIKKWIETRPV 204 >4FQU-A nrPDB Length = 313 Score = 57.4 bits (137), Expect = 5e-09, Method: Composition-based stats. Identities = 39/253 (15%), Positives = 78/253 (30%), Gaps = 40/253 (15%) Query: 22 GLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNK---------------------- 59 G +Y+ CP++HR ++ K + E++++++ N Sbjct: 43 GRYHLYAGFACPWAHRVLIMRALKGLE-EMISVSMVNAYMGENGWTFLPGDDVVPDSING 101 Query: 60 ----PEWYYTKHP----FGHIPVLETSQCQLI--YESVIACEYLDDAYPGRKLFPYDPYE 109 + Y P IP+L + I ES L+ A+ P D Y Sbjct: 102 ADYLYQVYTAADPTYTGRVTIPILWDKVEKRILNNESSEIIRILNSAFDDVGALPGDYYP 161 Query: 110 RARQKMLLELFCKVPHLTKECLVALRCGRECTNLKAALRQEFSNLEEILEY-QNTTFFGG 168 + + + +V + + A F L+ + E+ + G Sbjct: 162 AEFRPEIDRINARVYETLNNGVYRSGFATTQEAYEEAFYPLFDTLDWLEEHLTGREWLVG 221 Query: 169 TCISMIDYLLWPWFERLDVYG------ILDCVSHTPALRLWISAMKWDPTVCALLMDKSI 222 ++ D L+P R D L ++ P L + + V + + Sbjct: 222 DRLTEADIRLFPTLVRFDAIYHGHFKCNLRRIADYPNLSRLVGKLASHERVAPTINLRHA 281 Query: 223 FQGFLNLYFQNNP 235 + + NP Sbjct: 282 KAHYYGSHPSVNP 294 >2FHE-A nrPDB Length = 216 Score = 57.4 bits (137), Expect = 6e-09, Method: Composition-based stats. Identities = 30/186 (16%), Positives = 69/186 (37%), Gaps = 11/186 (5%) Query: 38 TRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGH----IPVLETSQCQLIYESVIACEYL 93 RL+L+ ++E + +W+ K G +P +C+ + +S+ Y+ Sbjct: 16 VRLLLEYLGEKYEEQIYERDDGEKWFSKKFELGLDLPNLPYYIDDKCK-LTQSLAILRYI 74 Query: 94 DDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECTNLKAALRQEFSN 153 D + + ERAR M+ + + + L Sbjct: 75 ADKHG---MIGTTSEERARVSMIEGAAVDLRQGISRISYQPKFEQLKEGYLKDLPTTMKM 131 Query: 154 LEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCVSHTPALRLWISAMKWDPTV 213 + L + GT +S +D++++ + + C+ H P L+ ++S ++ P++ Sbjct: 132 WSDFL--GKNPYLRGTSVSHVDFMVYEALDAIRYL-EPHCLDHFPNLQQFMSRIEALPSI 188 Query: 214 CALLMD 219 A + Sbjct: 189 KAYMES 194 >3IR4-A nrPDB Length = 218 Score = 57.0 bits (136), Expect = 6e-09, Method: Composition-based stats. Identities = 32/213 (15%), Positives = 64/213 (30%), Gaps = 41/213 (19%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGH--IPVLETSQCQ 81 +++Y CP+ + R++ K+I V +N+ + G +P+L+ + Sbjct: 4 MKLYIYDHCPFCVKARMIFGLKNIP---VELNVLQNDDEATPTRMIGQKMVPILQKDDSR 60 Query: 82 LIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECT 141 + ES+ Y+D+ L R + E KV + L+ Sbjct: 61 YLPESMDIVHYVDNLDGKPLLTGK------RNPAIEEWLRKVNGYVNQLLLPRFAKSAFD 114 Query: 142 N-LKAALRQEF--------SNLEEILEYQNT------------------TFFGGTCISMI 174 A RQ F + + L + +S Sbjct: 115 EFSTPAARQYFIRKKEASSGSFDNHLAHSAGLIKKIGDDLRLLDKLIVQPNAVNGELSED 174 Query: 175 DYLLWPWFERLDVYGILDCVSHTPALRLWISAM 207 D L+P L + + + + + M Sbjct: 175 DIHLFPLLRNLTLVAGIHWPT---KVADYRDNM 204 >3PPU-A nrPDB Length = 352 Score = 55.1 bits (131), Expect = 2e-08, Method: Composition-based stats. Identities = 45/281 (16%), Positives = 83/281 (29%), Gaps = 56/281 (19%) Query: 8 TLGKGSQPPG--PVPEGLIRIYSMRFCPYSHRTRLVLKAKDI------------------ 47 + QP G +G +Y CP++ RT +V K K + Sbjct: 60 SFRNWIQPNGDFTPEKGRYHLYVSYACPWATRTLIVRKLKGLEDFIGVTVVSPRMGSNGW 119 Query: 48 ------RHEVVNINLRNKPE----WYYTKHP----FGHIPVL-ETSQCQLI-YESVIACE 91 + + N + Y P +PVL + ++ ES Sbjct: 120 PFANVDPFPAADSDPLNNAQHVKDLYLKVKPDYDGRFTVPVLWDKHTGTIVNNESSEIIR 179 Query: 92 YLDDAYPGRKLFPYDPYE--------RARQKMLLELFCKVPHLTKECLVALRCGRECTNL 143 + A+ L P D + RA+ + + + + Sbjct: 180 MFNTAFNH--LLPEDKAKLDLYPESLRAKIDEVNDWVYDTVNNGVYKSGFASTQKAYEAA 237 Query: 144 KAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCV-------SH 196 L + LE++LE Q+ + G ++ D L+ R D + Sbjct: 238 VIPLFESLDRLEKMLEGQD--YLIGGQLTEADIRLFVTIVRFDPVYVTHFKCNLRTIRDG 295 Query: 197 TPALRLWISAMKW-DPTVCALLMDKSIFQGFLNLYFQNNPN 236 P L W+ + W +P + I + + NP+ Sbjct: 296 YPNLHRWMRKLYWGNPAFKDTCNFEHIKTHYFWSHTFINPH 336 >2WRT-A nrPDB Length = 218 Score = 55.1 bits (131), Expect = 3e-08, Method: Composition-based stats. Identities = 26/171 (15%), Positives = 61/171 (35%), Gaps = 11/171 (6%) Query: 58 NKPEWYYTKHPFGH----IPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQ 113 ++ +W K G +P +C+ + +SV Y+ D + + P ERAR Sbjct: 37 DREKWLGDKFNMGLDLPNLPYYIDDKCK-LTQSVAIMRYIADKHG---MLGSTPEERARI 92 Query: 114 KMLLELFCKVPHLTKECLVALRCGRECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISM 173 M+ + + + L L + + G+ +S Sbjct: 93 SMIEGAAMDLRMGFVRVCYNPKFEEVKGDYLKELPTTLKMWSNFL--GDRHYLTGSSVSH 150 Query: 174 IDYLLWPWFERLDVYGILDCVSHTPALRLWISAMKWDPTVCALLMDKSIFQ 224 +D++++ + + C+ P L+ + S ++ P + A + + + Sbjct: 151 VDFMVYEALDCIRYLAP-QCLEDFPKLKEFKSRIEDLPKIKAYMESEKFIK 200 >4LMW-A nrPDB Length = 251 Score = 54.3 bits (129), Expect = 4e-08, Method: Composition-based stats. Identities = 41/220 (18%), Positives = 72/220 (32%), Gaps = 43/220 (19%) Query: 33 PYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYT-------KHPFG----HIPVLETSQCQ 81 P + +TR VL K +++ + + K P G +PV++ + Sbjct: 23 PNTWKTRYVLNFKGLKYRTEWVEYPDIEAVCKQIGAPATEKKPDGRDHYTLPVIQDPNTK 82 Query: 82 LI-YESVIACEYLDDAYPG-RKLFPYDP-------YERARQKMLLELFCKVPHLTKECL- 131 + +S +YL+ YP +LFP Y+ AR +L+ +F V + L Sbjct: 83 AVVADSDAIAKYLESTYPDTPRLFPEGTRAFQHAFYQLARPSVLMPIFNIVVARVWKLLR 142 Query: 132 -------------VALRCGRECTNLKA--ALRQEFSNLEEILE---YQNTTFFGGTCISM 173 + + E + AL + ++ LE G ++ Sbjct: 143 PRSQEYFRATREQMLGKKLEEIGSEDDWNALESGLARIKSSLEANGAGKDLLLMGDRVTF 202 Query: 174 IDYLLWPWFERLDVYGILDCVSHTPALRL----WISAMKW 209 D L F L V + L L W M+ Sbjct: 203 ADLQLASLFIWLRVSAGEESEDWKRFLSLHEGKWAKFMQQ 242 >3KXO-A nrPDB Length = 202 Score = 54.3 bits (129), Expect = 4e-08, Method: Composition-based stats. Identities = 32/203 (15%), Positives = 64/203 (31%), Gaps = 14/203 (6%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQLI 83 ++ + R + DI++E I + PE T PFG IP+LE + Sbjct: 7 YKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPEIKSTL-PFGKIPILEV-DGLTL 64 Query: 84 YESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGREC--T 141 ++S+ YL L E+ +++ C ++ Sbjct: 65 HQSLAIARYL---TKNTDLAGNTEMEQCHVDAIVDTLDD----FMSCFPWAEKKQDVKEQ 117 Query: 142 NLKAALRQEFSNLEEILEY--QNTTFFGGTCISMIDYLLWPWFERLDVYGILDCVSHTPA 199 L +L + L+ + G ++ D+ W + D + + P Sbjct: 118 MFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADF-YWEICSTTLLVFKPDLLDNHPR 176 Query: 200 LRLWISAMKWDPTVCALLMDKSI 222 L ++ P V + + Sbjct: 177 LVTLRKKVQAIPAVANWIKRRPQ 199 >1U3I-A nrPDB Length = 211 Score = 52.8 bits (125), Expect = 1e-07, Method: Composition-based stats. Identities = 29/210 (13%), Positives = 70/210 (33%), Gaps = 16/210 (7%) Query: 21 EGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQC 80 I++ + R+ L A + +E I+ ++ P+ T P G +P ++ + Sbjct: 3 GEHIKVIYFDGRGRAESIRMTLVAAGVDYEDERISFQDWPKIKPTI-PGGRLPAVKVTDD 61 Query: 81 ----QLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRC 136 + + ES+ Y+ + + E + L+ V H + L+ + Sbjct: 62 HGHVKWMLESLAIARYMAKKH---HMMGETDEEYYSVEKLIGQAEDVEHEYHKTLM--KP 116 Query: 137 GRECTNLKAALRQE-----FSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGIL 191 E + + F+ + E L+ G +++ D +L + + Sbjct: 117 QEEKEKITKEILNGKVPVLFNMICESLKGSTGKLAVGDKVTLADLVLIAVIDHVTDLDKG 176 Query: 192 DCVSHTPALRLWISAMK-WDPTVCALLMDK 220 P + + P + L ++ Sbjct: 177 FLTGKYPEIHKHRENLLASSPRLAKYLSNR 206 >6GZF-A nrPDB Length = 341 Score = 52.8 bits (125), Expect = 1e-07, Method: Composition-based stats. Identities = 33/256 (12%), Positives = 73/256 (28%), Gaps = 43/256 (16%) Query: 22 GLIRIYSMRFCPYSHRTRLVLKAKDIRHE--------VVNINLRNKPE------------ 61 G +Y CP++HRT + K + + Sbjct: 54 GRYHLYVSYACPWAHRTLVTRTLKGLEDAISVSVVDPYRAEDGWQFTPEKEGCTHDHVHD 113 Query: 62 ------WYYTKHP----FGHIPVL-ETSQCQLIY-ESVIACEYLDDAYPGRKLFPYDPYE 109 Y P +PVL +T + ++ ES D + D Y Sbjct: 114 VDYLRELYVRAAPDVTCRVTVPVLWDTEEDTIVNNESEEIMRMFDTEFDEFADHTVDLYP 173 Query: 110 RARQKMLLELFCKVPHLTKECLVALRCGRECTNLKAALRQEFSNL---EEILEYQNTTFF 166 Q+ + ++ + + E A+ + F L +++L + + Sbjct: 174 EGYQEKVDQIIDNIYEPINNGVYRAGFATEQEPYDEAVAELFGALAHWDDVLA--DQRYL 231 Query: 167 GGTCISMIDYLLWPWFERLDVYG------ILDCVSHTPALRLWISAMKWDPTVCALLMDK 220 G ++ D ++ R D + + L ++ + + + Sbjct: 232 AGDRLTEADIAMFTTLVRFDNVYHTHFMCNVQYIREFDNLWPYLRDLYQTHGIAETVEMD 291 Query: 221 SIFQGFLNLYFQNNPN 236 I + + + NP+ Sbjct: 292 HITEHYYTTHPDVNPH 307 >6GCB-A nrPDB Length = 325 Score = 52.0 bits (123), Expect = 2e-07, Method: Composition-based stats. Identities = 43/243 (17%), Positives = 78/243 (32%), Gaps = 51/243 (20%) Query: 19 VPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNI----NLRNKPEW-YYTKHPFG--- 70 +G +Y CP++ RT +V K K + E+V + L + W + PF Sbjct: 43 PEKGRYHLYVAYSCPWATRTLIVRKIKGLE-EIVGVTIVSPLFSAHGWPFGDVSPFPGAE 101 Query: 71 -------------------------HIPVLETSQCQLIY--ESVIACEYLDDAYPGRKLF 103 +PVL + + + ES + A+ Sbjct: 102 ADPFYNAQYVRDLYLRADPKYEGRFTVPVLWDKKTETVVNNESSEIIRIFNTAFNE--FL 159 Query: 104 PYD-----PYERARQKMLLELFCKVPHLTKECLVALRCGRECTNLKAALRQEFSNLEEIL 158 P D Y A + + E+ V + +AA+ F +L+ + Sbjct: 160 PADKAAIHLYPEALKSEIDEINEWVYDTVNNGVYKAGFATTQQAYEAAVIPLFESLDRLE 219 Query: 159 EYQNTT-FFGGTCISMIDYLLWPWFERLD--VYGILDC-----VSHTPALRLWISAMKWD 210 + + G ++ D L+ R D G C PA+ LW+ + W+ Sbjct: 220 KILTGKDYLVGDQLTEADVRLFVTIIRFDPAYVGHFKCNLRTIRDGYPAIHLWLRKLYWN 279 Query: 211 PTV 213 + Sbjct: 280 NSA 282 >2DC5-A nrPDB Length = 231 Score = 52.0 bits (123), Expect = 2e-07, Method: Composition-based stats. Identities = 36/184 (19%), Positives = 64/184 (34%), Gaps = 20/184 (10%) Query: 35 SHRTRLVLKAKDIRHEVVNINLRNKP-----EWYYTKHPFGH----IPVLETSQCQLIYE 85 +H RL L+ D +E + + P +W K G +P L + I + Sbjct: 21 AHAIRLFLEYTDSSYEEKRYTMGDAPDYDQSQWLNEKFKLGLDFPNLPYLIDGSHK-ITQ 79 Query: 86 SVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECTNLKA 145 S YL + L ER R +L + L L + LK Sbjct: 80 SNAILRYLGRKH---NLCGETEEERIRVDILENQLMD----NRMVLARLCYNADFEKLKP 132 Query: 146 ALRQEFSNLEEILEY--QNTTFFGGTCISMIDYLLWPWFERLDVYGILDCVSHTPALRLW 203 ++ + + +F G I+ +D++ + ER V+ C+ P L+ + Sbjct: 133 GYLEQLPGMMRLYSEFLGKRPWFAGDKITFVDFIAYDVLERNQVF-EAKCLDAFPNLKDF 191 Query: 204 ISAM 207 I+ Sbjct: 192 IARF 195 >1HNA-A nrPDB Length = 217 Score = 51.7 bits (122), Expect = 3e-07, Method: Composition-based stats. Identities = 38/194 (19%), Positives = 72/194 (37%), Gaps = 20/194 (10%) Query: 35 SHRTRLVLKAKDIRHEVVNINLRNKP-----EWYYTKHPFGH----IPVLETSQCQLIYE 85 +H RL+L+ D +E + + P +W K G +P L + I + Sbjct: 13 AHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGTHK-ITQ 71 Query: 86 SVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECTNLKA 145 S Y+ + L E+ R+ +L F ++ L L + LK Sbjct: 72 SNAILRYIARKH---NLCGESEKEQIREDILENQFMD----SRMQLAKLCYDPDFEKLKP 124 Query: 146 ALRQEFSNLEEILEY--QNTTFFGGTCISMIDYLLWPWFERLDVYGILDCVSHTPALRLW 203 Q + ++ +F G I+ +D++ + ER V+ C+ P L+ + Sbjct: 125 EYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVF-EPSCLDAFPNLKDF 183 Query: 204 ISAMKWDPTVCALL 217 IS + + A + Sbjct: 184 ISRFEGLEKISAYM 197 >2GLR-A nrPDB Length = 209 Score = 51.7 bits (122), Expect = 3e-07, Method: Composition-based stats. Identities = 35/189 (18%), Positives = 64/189 (33%), Gaps = 9/189 (4%) Query: 35 SHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQLIYESVIACEYLD 94 + R L + + + EVV I+ + +G +P E +Y+S +L Sbjct: 16 AMRMLLADQGQSWKEEVVTIDTWMQG-LLKPTCLYGQLPKFEDGDLT-LYQSNAILRHLG 73 Query: 95 DAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECTNLKAALRQEFSNL 154 + L+ + E A+ M+ + + + + +K AL Sbjct: 74 RSLG---LYGKNQREAAQMDMVNDGVEDLRGKYVTLIYTNYENGKNDYVK-ALPGHLKPF 129 Query: 155 EEIL--EYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCVSHTPALRLWISAMKWDPT 212 E +L F G IS DY L V C+ + P L +++ + P Sbjct: 130 ETLLSQNQGGKAFIVGDQISFADYNLLDLLLIHQVLAP-GCLDNFPLLSAYVARLSARPK 188 Query: 213 VCALLMDKS 221 + A L Sbjct: 189 IKAFLSSPE 197 >2CA8-A nrPDB Length = 211 Score = 51.7 bits (122), Expect = 3e-07, Method: Composition-based stats. Identities = 27/193 (13%), Positives = 64/193 (33%), Gaps = 16/193 (8%) Query: 38 TRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQC----QLIYESVIACEYL 93 R+ L A + +E I+ ++ P+ T P G +P ++ + + + ES+ Y+ Sbjct: 20 IRMTLVAAGVNYEDERISFQDWPKIKPTI-PGGRLPAVKITDNHGHVKWMVESLAIARYM 78 Query: 94 DDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECTNLKAALRQE--- 150 + + E + L+ + H + L+ + E + + Sbjct: 79 AKKH---HMMGGTEEEYYNVEKLIGQAEDLEHEYYKTLM--KPEEEKQKIIKEILNGKVP 133 Query: 151 --FSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCVSHTPALRLWISAMK 208 + E L+ G +++ D +L + + P + + Sbjct: 134 VLLDIICESLKASTGKLAVGDKVTLADLVLIAVIDHVTDLDKEFLTGKYPEIHKHRENLL 193 Query: 209 -WDPTVCALLMDK 220 P + L D+ Sbjct: 194 ASSPRLAKYLSDR 206 >1GSQ-A nrPDB Length = 202 Score = 51.3 bits (121), Expect = 4e-07, Method: Composition-based stats. Identities = 31/205 (15%), Positives = 67/205 (32%), Gaps = 12/205 (5%) Query: 23 LIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQL 82 ++ + R VL A + + + P T + +PVL+ Sbjct: 2 KYTLHYFPLMGRAELCRFVLAAHGEEFTDRVVEMADWPNLKATMY-SNAMPVLDI-DGTK 59 Query: 83 IYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGREC-- 140 + +S+ +L + L E+ R + E + + + A +E Sbjct: 60 MSQSMCIARHLAREFG---LDGKTSLEKYRVDEITETLQDIFNDVVKIKFAPEAAKEAVQ 116 Query: 141 TNLKAALRQEFSNLEEILEYQNTT--FFGGTCISMIDYLLWPWFER-LDVYGILDCVSHT 197 N + + ++ LE +L FF G +++ D + E L + + Sbjct: 117 QNYEKSCKRLAPFLEGLLVSNGGGDGFFVGNSMTLADLHCYVALEVPLKH--TPELLKDC 174 Query: 198 PALRLWISAMKWDPTVCALLMDKSI 222 P + + P + A L + + Sbjct: 175 PKIVALRKRVAECPKIAAYLKKRPV 199 >5Y9Z-A nrPDB Length = 199 Score = 51.3 bits (121), Expect = 4e-07, Method: Composition-based stats. Identities = 36/206 (17%), Positives = 73/206 (35%), Gaps = 20/206 (9%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQLI 83 ++ + R + DI++E I + P+ T PFG IPVLE + Sbjct: 4 YKLLYFNMRGRAEIIRYIFAYLDIKYEDHRIEQADWPKIKPTL-PFGKIPVLEVE-GLTL 61 Query: 84 YESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECTNL 143 ++S+ YL L E+ + +++ L E +L Sbjct: 62 HQSLAIARYL---TKNTDLAGKTELEQCQVDAVVDTLDDFMSLFPWA-------EENQDL 111 Query: 144 KAA-----LRQEFSNLEEILEY--QNTTFFGGTCISMIDYLLWPWFERLDVYGILDCVSH 196 K L ++ +L + L+ + +F G ++ D+ W + D + Sbjct: 112 KERTFNDLLTRQAPHLLKDLDTYLGDKEWFIGNYVTWADF-YWDICSTTLLVLKPDLLGI 170 Query: 197 TPALRLWISAMKWDPTVCALLMDKSI 222 P L + ++ P + A ++ + Sbjct: 171 YPRLVSLRNKVQAIPAISAWILKRPQ 196 >4GTU-A nrPDB Length = 217 Score = 51.3 bits (121), Expect = 4e-07, Method: Composition-based stats. Identities = 33/192 (17%), Positives = 66/192 (34%), Gaps = 16/192 (8%) Query: 35 SHRTRLVLKAKDIRHEVVNINLRNKP-----EWYYTKHPFGH----IPVLETSQCQLIYE 85 +H RL+L+ D +E + + P +W K G +P L I + Sbjct: 13 AHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL-IDGAHKITQ 71 Query: 86 SVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECTNLKA 145 S Y+ + L E+ R +L V + + + Sbjct: 72 SNAILCYIARKH---NLCGETEEEKIRVDILENQAMDVSNQLARVCYSPDFEKLKPEYLE 128 Query: 146 ALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCVSHTPALRLWIS 205 L + + L +F G I+ +D+L + + ++ +C+ P L+ +IS Sbjct: 129 ELPTMMQHFSQFL--GKRPWFVGDKITFVDFLAYDVLDLHRIF-EPNCLDAFPNLKDFIS 185 Query: 206 AMKWDPTVCALL 217 + + A + Sbjct: 186 RFEGLEKISAYM 197 >2YV7-A nrPDB Length = 260 Score = 51.3 bits (121), Expect = 4e-07, Method: Composition-based stats. Identities = 37/192 (19%), Positives = 63/192 (32%), Gaps = 18/192 (9%) Query: 43 KAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGR-K 101 + K I +V ++++ P + T H P+L I E+ ++ PG Sbjct: 55 ELKTISLKVTTVDMQKPPPDFRTNFEATHPPIL-IDNGLAILENEKIERHIMKNIPGGYN 113 Query: 102 LFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECTNLKAALRQEFSNLEEILEYQ 161 LF D E+ + +L + + L E N AL + + L + Sbjct: 114 LFVQD----------KEVATLIENLYVKLKLMLVKKDEAKN--NALLSHLRKINDHLSAR 161 Query: 162 NTTFFGGTCISMIDYLLWPWFERLDVYGIL----DCVSHTPALRLWISAMKWDPTVCALL 217 NT F G + D L P + + V G + +H AL ++ M Sbjct: 162 NTRFLTGDTMCCFDCELMPRLQHIRVAGKYFVDFEIPTHLTALWRYMYHMYQLDAFTQSC 221 Query: 218 MDKSIFQGFLNL 229 L Sbjct: 222 PADQDIINHYKL 233 >1FHE-A nrPDB Length = 217 Score = 50.1 bits (118), Expect = 9e-07, Method: Composition-based stats. Identities = 32/190 (16%), Positives = 68/190 (35%), Gaps = 11/190 (5%) Query: 35 SHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGH----IPVLETSQCQLIYESVIAC 90 + RL L+ +E ++ +W K G +P +C+ + +SV Sbjct: 13 AQPVRLFLEYLGEEYEEHLYGRDDREKWMSEKFNMGLDLPNLPYYIDDKCK-LTQSVAIM 71 Query: 91 EYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECTNLKAALRQE 150 Y+ D + + P ERAR M+ + + L + Sbjct: 72 RYIADKHG---MLGTTPEERARISMIEGAAMDLRIGFGRVCYNPKFEEVKEEYVKELPKT 128 Query: 151 FSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCVSHTPALRLWISAMKWD 210 + L + + G+ +S +D++L+ + + C+ P L+ + S ++ Sbjct: 129 LKMWSDFL--GDRHYLTGSSVSHVDFMLYETLDSIRYLAPH-CLDEFPKLKEFKSRIEAL 185 Query: 211 PTVCALLMDK 220 P + A + K Sbjct: 186 PKIKAYMESK 195 >6GC9-A nrPDB Length = 327 Score = 50.1 bits (118), Expect = 9e-07, Method: Composition-based stats. Identities = 39/245 (15%), Positives = 73/245 (29%), Gaps = 55/245 (22%) Query: 19 VPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP------------------ 60 +G +Y CP++ RT +V K K + E +++++ + Sbjct: 44 PEKGRYHLYVSYACPWATRTLIVRKIKGLE-EFIDVSVVSPRMGAHGWPFANVDAFPGAD 102 Query: 61 -----------EWYYTKHP----FGHIPVLETSQCQLIY--ESVIACEYLDDAYPGRKLF 103 + Y +P +P+L + I ES + A+ + Sbjct: 103 ADPLFGAEHVKDLYMRVNPDYEGRFTVPILWDKKTSAIVNNESSEIIRMFNTAFNDQ--L 160 Query: 104 PYDPYE--------RARQKMLLELFCKVPHLTKECLVALRCGRECTNLKAALRQEFSNLE 155 P D R + E + + L + LE Sbjct: 161 PSDKAAIDLYPEALRGEIDGINEWVYDTVNNGVYKSGFATSQKAYEAAVVPLFESLDRLE 220 Query: 156 EILEYQNTTFFGGTCISMIDYLLWPWFERLD--VYGILDC-----VSHTPALRLWISAMK 208 +IL + G ++ D L+ R D G C PA+ LW+ + Sbjct: 221 KILT--GKDYLVGDQLTEADIRLFVTIVRFDPVYVGHFKCNIRTIRDGYPAIDLWMRKLY 278 Query: 209 WDPTV 213 W+ + Sbjct: 279 WNNSA 283 >4LMV-A nrPDB Length = 252 Score = 50.1 bits (118), Expect = 1e-06, Method: Composition-based stats. Identities = 23/108 (21%), Positives = 42/108 (38%), Gaps = 17/108 (15%) Query: 19 VPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTK--HPFGH----- 71 ++ + P + + R L K I+++ + + + P G Sbjct: 10 PSNDTLK--QSPWSPNTWKIRYALNIKGIKYKTEWVEYPDIEDVVKKLGGKPTGKKPDGR 67 Query: 72 ----IPVLETSQCQLIYESVI-ACEYLDDAYPG-RKLFPY--DPYERA 111 +PV+ + + E I +YLDDAYP +LFP D ++ A Sbjct: 68 DHYTVPVIYDPNTKTVVEDGIKIAKYLDDAYPDTPRLFPAGTDAFQAA 115 >18GS-A nrPDB Length = 210 Score = 49.7 bits (117), Expect = 1e-06, Method: Composition-based stats. Identities = 35/188 (18%), Positives = 61/188 (32%), Gaps = 11/188 (5%) Query: 37 RTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDDA 96 R L + + + EVV + + +G +P + +Y+S +L Sbjct: 19 RMLLADQGQSWKEEVVTVETWQEGS-LKASCLYGQLPKFQDGDLT-LYQSNTILRHLGRT 76 Query: 97 YPGRKLFPYDPYERARQKMLLELFCKVP-HLTKECLVALRCGRECTNLKAALRQEFSNLE 155 L+ D E A M+ + + G++ + AL + E Sbjct: 77 LG---LYGKDQQEAALVDMVNDGVEDLRCKYISLIYTNYEAGKD--DYVKALPGQLKPFE 131 Query: 156 EIL--EYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCVSHTPALRLWISAMKWDPTV 213 +L TF G IS DY L +V C+ P L ++ + P + Sbjct: 132 TLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAP-GCLDAFPLLSAYVGRLSARPKL 190 Query: 214 CALLMDKS 221 A L Sbjct: 191 KAFLASPE 198 >2PBJ-A nrPDB Length = 290 Score = 48.2 bits (113), Expect = 3e-06, Method: Composition-based stats. Identities = 19/95 (20%), Positives = 39/95 (41%), Gaps = 9/95 (9%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQC--- 80 + +Y + CP+ + R L + ++VV +N + E + +P+L + Sbjct: 15 LTLYQYKTCPFCSKVRAFLDFHALPYQVVEVNPVLRAE--IKFSSYRKVPILVAQEGESS 72 Query: 81 QLIYESVIACE----YLDDAYPGRKLFPYDPYERA 111 Q + +S + YL P ++ Y P +A Sbjct: 73 QQLNDSSVIISALKTYLVSGQPLEEIITYYPAMKA 107 Score = 32.0 bits (71), Expect = 0.24, Method: Composition-based stats. Identities = 6/47 (12%), Positives = 18/47 (38%) Query: 161 QNTTFFGGTCISMIDYLLWPWFERLDVYGILDCVSHTPALRLWISAM 207 ++ F GG ++ D ++ ++ D + ++ W + Sbjct: 233 KDRPFMGGQKPNLADLAVYGVLRVMEGLDAFDDLMQHTHIQPWYLRV 279 >4PTS-A nrPDB Length = 348 Score = 47.8 bits (112), Expect = 4e-06, Method: Composition-based stats. Identities = 46/260 (17%), Positives = 77/260 (29%), Gaps = 46/260 (17%) Query: 18 PVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNI---NLRNKPEWYYTKHPFGHIPV 74 PV G R+ + R CP+++RT +V + + + + +K W + P G PV Sbjct: 42 PVEPGRYRLIAARACPWANRTLIVRRLLGLENVLSLGLCGPTHDKNSWTFDLDPGGVDPV 101 Query: 75 LETSQCQLIYESV-----------IACEY--------------LD--------DAYPGRK 101 L + + YE E +D + Sbjct: 102 LGIPRLKDAYEKRFPGYPKGITVPAVVEIATGEVVTNDFPQITIDFSLEWTAYHRDGAPQ 161 Query: 102 LFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECTNLKAALRQEFSNLEEILEYQ 161 L+P + RA + + + L + L E L Q Sbjct: 162 LYPE--HLRAEIDEVSKGIYTEVNNGVYRCGFAGSQDAYDAAYDRLFTKLDELSERLAQQ 219 Query: 162 NTTFFGGTCISMIDYLLWPWFERLDVY--GILDC----VSHTPALRLWISAMKWDPTVCA 215 + G I+ D L+ R D G C +S P L + + P Sbjct: 220 R--YLVGDTITEADVRLFTTLARFDAVYHGHFKCNRSKLSEMPVLWAYARDLFQTPGFGD 277 Query: 216 LLMDKSIFQGFLNLYFQNNP 235 I Q + ++ NP Sbjct: 278 TTDFTQIKQHYYIVHSDINP 297 >3M1G-A nrPDB Length = 362 Score = 47.0 bits (110), Expect = 8e-06, Method: Composition-based stats. Identities = 44/263 (16%), Positives = 80/263 (30%), Gaps = 52/263 (19%) Query: 18 PVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEV-------------------------V 52 PV G R+ + R CP++HRT + + + + + V Sbjct: 56 PVEAGRYRLVAARACPWAHRTVITRRLLGLENVISLGLTGPTHDVRSWTFDLDPNHLDPV 115 Query: 53 NINLRNKPEWYYTK--HPFG-HIPVLETSQCQLI----YESVIACEYLDDAY----PGRK 101 R + ++ +P G +P L + + Y S+ L+ Sbjct: 116 LQIPRLQDAYFNRFPDYPRGITVPALVEESSKKVVTNDYPSITIDFNLEWKQFHREGAPN 175 Query: 102 LFPYDPYER---ARQKMLLELFCKVPHLTKECLVALRCGRECTNLKAALRQEFSNLEEIL 158 L+P + E +++ E+ V L LE+ L Sbjct: 176 LYPAELREEMAPVMKRIFTEVNNGVYRTG-----FAGSQEAHNEAYKRLWVALDWLEDRL 230 Query: 159 EYQNTTFFGGTCISMIDYLLWPWFERLDVY--GILDC----VSHTPALRLWISAMKWDPT 212 + G I+ D L+P R D G C ++ P L ++ + P Sbjct: 231 --STRRYLMGDHITEADIRLYPTLVRFDAVYHGHFKCGRNKITEMPNLWGYLRDLFQTPG 288 Query: 213 VCALLMDKSIFQGFLNLYFQNNP 235 I Q + + + NP Sbjct: 289 FGDTTDFTEIKQHYYITHAEINP 311 >1M0U-A nrPDB Length = 249 Score = 47.0 bits (110), Expect = 8e-06, Method: Composition-based stats. Identities = 30/181 (16%), Positives = 63/181 (34%), Gaps = 14/181 (7%) Query: 48 RHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDP 107 +E V + P T P G +PVLE + +++S+ +L L P Sbjct: 74 EYEDVRVTRDEWPALKPTM-PMGQMPVLEV-DGKRVHQSISMARFLAKTVG---LCGATP 128 Query: 108 YERARQKMLLELFCKVPHLTKECLVALRCGRECTNLKAALRQE------FSNLEEILEYQ 161 +E + ++++ K +V+ E K LE+ ++ Sbjct: 129 WEDLQIDIVVDTIND--FRLKIAVVSYEPEDEIKEKKLVTLNAEVIPFYLEKLEQTVKDN 186 Query: 162 NTTFFGGTCISMIDYLLWPWFERLDVYGILDCVSHTPALRLWISAMKWDPTVCALLMDKS 221 + G ++ D + ++ D + PALR + A+ + A + + Sbjct: 187 DGHLALGK-LTWADVYFAGITDYMNYMVKRDLLEPYPALRGVVDAVNALEPIKAWIEKRP 245 Query: 222 I 222 + Sbjct: 246 V 246 >1DUG-A nrPDB Length = 234 Score = 46.6 bits (109), Expect = 8e-06, Method: Composition-based stats. Identities = 25/152 (16%), Positives = 54/152 (35%), Gaps = 14/152 (9%) Query: 77 TSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRC 136 + +S+ Y+ D + + P ERA ML + + + Sbjct: 58 IDGDVKLTQSMAIIRYIADKH---NMLGGCPKERAEISMLEGAVLDIRYGVSR----IAY 110 Query: 137 GRECTNLKAALRQEFSNLEEILEY--QNTTFFGGTCISMIDYLLWPWFERLDVYGILD-- 192 ++ LK + + ++ E + T+ G ++ D++L+ + LDV +D Sbjct: 111 SKDFETLKVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTHPDFMLY---DALDVVLYMDPM 167 Query: 193 CVSHTPALRLWISAMKWDPTVCALLMDKSIFQ 224 C+ P L + ++ P + L Sbjct: 168 CLDAFPKLVCFKKRIEAIPQIDKYLKSSKYIA 199 >4Q5Q-A nrPDB Length = 219 Score = 46.6 bits (109), Expect = 9e-06, Method: Composition-based stats. Identities = 30/198 (15%), Positives = 66/198 (33%), Gaps = 16/198 (8%) Query: 33 PYSHRTRLVLKAKDIR-----HEVVNINLRNKPEWYYTKHPFGH----IPVLETSQCQLI 83 Y+ RL+L + +++ ++ EW K G +P + + Sbjct: 13 GYAQPIRLLLTYSGVDFVDKRYQIGPAPDFDRSEWLNEKFNLGLDFPNLPYYIDGDMK-M 71 Query: 84 YESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECTNL 143 ++ YL Y KL + +E R M + + C + + Sbjct: 72 TQTFAILRYLGRKY---KLNGSNDHEEIRISMAEQQTEDMMAAMIRVCYDANCDKLKPDY 128 Query: 144 KAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCVSHTPALRLW 203 +L + + + F G IS +D+ L+ + + V + + L+ + Sbjct: 129 LKSLPDCLKLMSKFVGEHA--FIAGANISYVDFNLYEYLCHVKVM-VPEVFGQFENLKRY 185 Query: 204 ISAMKWDPTVCALLMDKS 221 + M+ P V + + Sbjct: 186 VERMESLPRVSDYIKKQQ 203 >1BG5-A nrPDB Length = 254 Score = 46.6 bits (109), Expect = 1e-05, Method: Composition-based stats. Identities = 25/152 (16%), Positives = 54/152 (35%), Gaps = 14/152 (9%) Query: 77 TSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRC 136 + +S+ Y+ D + + P ERA ML + + + Sbjct: 59 IDGDVKLTQSMAIIRYIADKH---NMLGGCPKERAEISMLEGAVLDIRYGVSR----IAY 111 Query: 137 GRECTNLKAALRQEFSNLEEILEY--QNTTFFGGTCISMIDYLLWPWFERLDVYGILD-- 192 ++ LK + + ++ E + T+ G ++ D++L+ + LDV +D Sbjct: 112 SKDFETLKVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTHPDFMLY---DALDVVLYMDPM 168 Query: 193 CVSHTPALRLWISAMKWDPTVCALLMDKSIFQ 224 C+ P L + ++ P + L Sbjct: 169 CLDAFPKLVCFKKRIEAIPQIDKYLKSSKYIA 200 >1B8X-A nrPDB Length = 280 Score = 46.6 bits (109), Expect = 1e-05, Method: Composition-based stats. Identities = 25/152 (16%), Positives = 54/152 (35%), Gaps = 14/152 (9%) Query: 77 TSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRC 136 + +S+ Y+ D + + P ERA ML + + + Sbjct: 58 IDGDVKLTQSMAIIRYIADKH---NMLGGCPKERAEISMLEGAVLDIRYGVSR----IAY 110 Query: 137 GRECTNLKAALRQEFSNLEEILEY--QNTTFFGGTCISMIDYLLWPWFERLDVYGILD-- 192 ++ LK + + ++ E + T+ G ++ D++L+ + LDV +D Sbjct: 111 SKDFETLKVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTHPDFMLY---DALDVVLYMDPM 167 Query: 193 CVSHTPALRLWISAMKWDPTVCALLMDKSIFQ 224 C+ P L + ++ P + L Sbjct: 168 CLDAFPKLVCFKKRIEAIPQIDKYLKSSKYIA 199 >4BVY-B nrPDB Length = 186 Score = 46.3 bits (108), Expect = 1e-05, Method: Composition-based stats. Identities = 25/147 (17%), Positives = 45/147 (30%), Gaps = 16/147 (10%) Query: 71 HIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKEC 130 IPVL+T+ + +L L E+A + LE Sbjct: 41 QIPVLQTNDGPSLTGLTTIAAHLVKQANKEYLLGSTAEEKAIVQQWLEYRVTQV------ 94 Query: 131 LVALRCGRECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGI 190 + + K + +L LE + + G ++ D LL+ R V Sbjct: 95 --------DGHSSKNDIHTLLKDLNSYLE--DKVYLTGYNFTLADILLYYGLHRFIVDLT 144 Query: 191 LDCVSHTPALRLWISAMKWDPTVCALL 217 + + W S ++ P + L Sbjct: 145 VQEKEKYLNVSRWFSHIQHYPGIRQHL 171 >1XWK-A nrPDB Length = 218 Score = 46.3 bits (108), Expect = 1e-05, Method: Composition-based stats. Identities = 33/192 (17%), Positives = 64/192 (33%), Gaps = 16/192 (8%) Query: 35 SHRTRLVLKAKDIRHEVVNINLRNKP-----EWYYTKHPFGH----IPVLETSQCQLIYE 85 +H RL+L+ D +E + + P +W K G +P L I + Sbjct: 14 AHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYL-IDGAHKITQ 72 Query: 86 SVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECTNLKA 145 S Y+ + L E+ R +L + Sbjct: 73 SNAILCYIARKH---NLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKPKYLE 129 Query: 146 ALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCVSHTPALRLWIS 205 L ++ E L +F G I+ +D+L++ + ++ C+ P L+ +IS Sbjct: 130 ELPEKLKLYSEFL--GKRPWFAGNKITFVDFLVYDVLDLHRIF-EPKCLDAFPNLKDFIS 186 Query: 206 AMKWDPTVCALL 217 + + A + Sbjct: 187 RFEGLEKISAYM 198 >5FWG-A nrPDB Length = 217 Score = 45.9 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 36/202 (17%), Positives = 70/202 (34%), Gaps = 36/202 (17%) Query: 35 SHRTRLVLKAKDIRHEVVNINLRNKP-----EWYYTKHPFGH----IPVLETSQCQLIYE 85 +H RL+L+ D +E + + P +W K G +P L + I + Sbjct: 13 THPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYL-IDGSRKITQ 71 Query: 86 SVIACEYLDDAYPGRKLFPYDPYERARQ----------KMLLELFCKVPHLTKECLVALR 135 S YL + L ER R +M L + C P K+ L+ Sbjct: 72 SNAIMRYLARKH---HLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEKQKPEFLK 128 Query: 136 CGRECTNLKAALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCVS 195 E L + +F G ++ +D+L + ++ ++ C+ Sbjct: 129 TIPEKMKLYSEFL------------GKRPWFAGDKVTYVDFLAYDILDQYHIF-EPKCLD 175 Query: 196 HTPALRLWISAMKWDPTVCALL 217 P L+ +++ + + A + Sbjct: 176 AFPNLKDFLARFEGLKKISAYM 197 >3GTU-B nrPDB Length = 224 Score = 45.1 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 32/208 (15%), Positives = 73/208 (35%), Gaps = 20/208 (9%) Query: 21 EGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP-----EWYYTKHPFGH---- 71 E + + +H RL+L+ D +E P +W K Sbjct: 3 ESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPN 62 Query: 72 IPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECL 131 +P L + + I +S Y+ + + E+ R ++ + L Sbjct: 63 LPYLLDGKNK-ITQSNAILRYIARKH---NMCGETEEEKIRVDIIENQVMD----FRTQL 114 Query: 132 VALRCGRECTNLKAALRQEF-SNLEEILEYQNT-TFFGGTCISMIDYLLWPWFERLDVYG 189 + L + LK +E L++ + ++F G ++ +D+L + ++ ++ Sbjct: 115 IRLCYSSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIF- 173 Query: 190 ILDCVSHTPALRLWISAMKWDPTVCALL 217 C+ P L+ ++ + + A L Sbjct: 174 DPKCLDEFPNLKAFMCRFEALEKIAAYL 201 >1B4P-A nrPDB Length = 217 Score = 45.1 bits (105), Expect = 3e-05, Method: Composition-based stats. Identities = 33/182 (18%), Positives = 64/182 (35%), Gaps = 16/182 (8%) Query: 35 SHRTRLVLKAKDIRHEVVNINLRNKP-----EWYYTKHPFGH----IPVLETSQCQLIYE 85 +H RL+L+ D +E + + P +W K G +P L + I + Sbjct: 13 THPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYL-IDGSRKITQ 71 Query: 86 SVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECTNLKA 145 S YL + L ER R +L + R+ Sbjct: 72 SNAIMRYLARKH---HLCGETEEERIRVDVLENQAMDTRLQLAMVCYSPDFERKKPEYLE 128 Query: 146 ALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCVSHTPALRLWIS 205 L ++ E L +F G I+ +D+L++ ++ ++ C+ P L+ +++ Sbjct: 129 GLPEKMKLYSEFL--GKQPWFAGNKITYVDFLVYDVLDQHRIF-EPKCLDAFPNLKDFVA 185 Query: 206 AM 207 Sbjct: 186 RF 187 >4G0L-A nrPDB Length = 328 Score = 44.7 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 36/218 (16%), Positives = 64/218 (29%), Gaps = 37/218 (16%) Query: 22 GLIRIYSMRFCPYSHRTRLVLKAKDIR--------HEVVNINLRNKP------------- 60 +Y CP++HRT ++ K K + + ++ N Sbjct: 53 DRYHLYVSLACPWAHRTLIMRKLKGLEPFISVSVVNPLMLENGWTFDDSFPGATGDTLYQ 112 Query: 61 -----EWYYTKHP----FGHIPVLETSQCQLIY--ESVIACEYLDDAYPGRKLFPYDPYE 109 + Y P +PVL + I ES + A+ D Y Sbjct: 113 NEFLYQLYLHADPHYSGRVTVPVLWDKKNHTIVSNESAEIIRMFNTAFDALGAKAGDYYP 172 Query: 110 RARQKMLLELFCKVPHLTKECLVALRCGRECTNLKAALRQEFSNL---EEILEYQNTTFF 166 A Q + EL + + A+ + F +L E+IL + Sbjct: 173 PALQTKIDELNGWIYDTVNNGVYKAGFATSQEAYDEAVAKVFESLARLEQILGQHR--YL 230 Query: 167 GGTCISMIDYLLWPWFERLDVYGILDCVSHTPALRLWI 204 G ++ D LW R D + + ++ Sbjct: 231 TGNQLTEADIRLWTTLVRFDPVYVTHFKCDKHRISDYL 268 >2WDU-A nrPDB Length = 211 Score = 44.3 bits (103), Expect = 5e-05, Method: Composition-based stats. Identities = 32/196 (16%), Positives = 62/196 (31%), Gaps = 23/196 (11%) Query: 25 RIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLET--SQCQL 82 +++ +F + RL+L ++ E + P T P G +P+L+ +L Sbjct: 7 KLWYFQFRGRAEPIRLLLTCAGVKFEDYQFTMDQWPTIKPTL-PGGRVPLLDVTGPDGKL 65 Query: 83 --IYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGREC 140 ES+ L + K+ ++ + + L +E R Sbjct: 66 RRYQESMAIARLLARQF---KMMGETD---EEYYLIERIIGECEDLYREVYTIFRT---P 116 Query: 141 TNLKAALRQEFSN---------LEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGIL 191 K A +EF + E LE G I++ D L+ + Sbjct: 117 QGEKEAKIKEFKENNGPTLLKLVSESLESSGGKHVAGNRITLGDLFLFTTLTHVMETVPG 176 Query: 192 DCVSHTPALRLWISAM 207 P L + ++ Sbjct: 177 FLEQKFPKLHEFHKSL 192 >5AN1-A nrPDB Length = 219 Score = 42.8 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 35/203 (17%), Positives = 62/203 (30%), Gaps = 24/203 (11%) Query: 35 SHRTRLVLKAKDIRHEVVNINLRNKP-----EWYYTKHPFGH----IPVLETSQCQLIYE 85 RL+L E N + + P EW K G +P + I + Sbjct: 14 CQPIRLMLGYTGTEFEEKNYPVGDAPDYDKSEWLAVKFKLGLAFPNLPYYIDGDVK-ITQ 72 Query: 86 SVIACEYLDDAYPGRKLFPYDPYERARQKMLL-ELFCKVPHLTKECLVALRCGRECTNLK 144 S YL + L P E R M+ +L T Sbjct: 73 SKAIMRYLARKHG---LCGTTPEELVRTDMIECQLTDMHEAFFTVTYEHYEQKDAYTASL 129 Query: 145 AALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILD--CVSHTPALRL 202 A +++S+ + +F G ++ ID+L + E D + LD C+ L+ Sbjct: 130 PAKLRQYSDFL-----GSRPWFAGDKLTYIDFLAY---EIFDQHLSLDRTCLDGFKNLQA 181 Query: 203 WISAMKWDPTVCALLMDKSIFQG 225 + + + + + Sbjct: 182 FQKRFEDLEAIKKYMASPKFLKK 204 >3GRX-A nrPDB Length = 82 Score = 40.5 bits (93), Expect = 7e-04, Method: Composition-based stats. Identities = 14/56 (25%), Positives = 26/56 (46%), Gaps = 1/56 (1%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINL-RNKPEWYYTKHPFGHIPVLETS 78 + IY+ CPYSHR + +L +K + + + I+ K E + +P + Sbjct: 3 VEIYTKETCPYSHRAKALLSSKGVSFQELPIDGNAAKREEMIKRSGRTTVPQIFID 58 >2X8H-A nrPDB Length = 598 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 14/71 (19%), Positives = 29/71 (40%), Gaps = 5/71 (7%) Query: 26 IYSMRFCPYSHRTRLVLKAKDIRHEVVNIN-LRNKPEW---YYTKHPFGHIPVLETSQCQ 81 ++S CPY + + VL I+H + ++ L N + +P + + + Sbjct: 22 LFSKTTCPYCKKVKDVLAEAKIKHATIELDQLSNGSAIQKCLASFSKIETVPQMFV-RGK 80 Query: 82 LIYESVIACEY 92 I +S +Y Sbjct: 81 FIGDSQTVLKY 91 >4USS-A nrPDB Length = 325 Score = 38.9 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 41/268 (15%), Positives = 73/268 (27%), Gaps = 50/268 (18%) Query: 18 PVPEGLIRIYSMRFCPYSHRTRLVLKAKDIR-----HEVVNINLRNKPEW---------- 62 P G +Y CP++ R LK K + V I R K Sbjct: 35 PPESGRYHLYVSYACPWASRCLAYLKIKGLEKAIAFTSVKPIWERTKESDEHMGWVFPAS 94 Query: 63 -----------------------YYTKHPFGH--IPVLETSQCQLIY--ESVIACEYLDD 95 + + G +PVL + + I ES + Sbjct: 95 ETEEAGAEPDTLNGARSIRELYELASTNYAGKYTVPVLWDKKLKTIVNNESSEIIRMFNT 154 Query: 96 AYPGRKLFPY-DPYERARQKMLLELFCKVPHLTKECLVALRCGRECTNLKAALRQEFSNL 154 + D Y Q + E V + R+ + A Q + L Sbjct: 155 EFNDIAENAALDLYPSHLQAQIDETNGWVYDGINNGVYKCGFARKQGPYEEAAIQLYEAL 214 Query: 155 EEILEYQNTT-FFGGTCISMIDYLLWPWFERLDVYG------ILDCVSHTPALRLWISAM 207 ++ E + G +S D L+ R D + P + + + Sbjct: 215 DKCEEILGRQRYICGNTLSEADIKLFVTLIRFDEVYAVHFKCNKKLLRDYPNMFNYTKDI 274 Query: 208 KWDPTVCALLMDKSIFQGFLNLYFQNNP 235 P + + + + I + + + NP Sbjct: 275 FQIPGMSSTVNMQHIKRHYYGSHPTVNP 302 >1GSU-A nrPDB Length = 219 Score = 38.2 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 26/192 (13%), Positives = 64/192 (33%), Gaps = 16/192 (8%) Query: 35 SHRTRLVLKAKDIRHEVVNINLRNKPE-----WYYTKHPFGH----IPVLETSQCQLIYE 85 +H RL+L+ + ++ P+ W K G +P L + + + Sbjct: 13 AHAIRLLLEYTETPYQERRYKAGPAPDFDPSDWTNEKEKLGLDFPNLPYLIDGDVK-LTQ 71 Query: 86 SVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECTNLKA 145 S Y+ + + E+ R +L + + + Sbjct: 72 SNAILRYIARKH---NMCGETEVEKQRVDVLENHLMDLRMAFARLCYSPDFEKLKPAYLE 128 Query: 146 ALRQEFSNLEEILEYQNTTFFGGTCISMIDYLLWPWFERLDVYGILDCVSHTPALRLWIS 205 L + L L ++ +F G ++ +D+L + ++ ++ + DC L ++ Sbjct: 129 QLPGKLRQLSRFLGSRS--WFVGDKLTFVDFLAYDVLDQQRMF-VPDCPELQGNLSQFLQ 185 Query: 206 AMKWDPTVCALL 217 + + A + Sbjct: 186 RFEALEKISAYM 197 >5LKB-A nrPDB Length = 378 Score = 37.4 bits (85), Expect = 0.005, Method: Composition-based stats. Identities = 33/228 (14%), Positives = 69/228 (30%), Gaps = 49/228 (21%) Query: 49 HEVVNI-NLRNKPEWYYTKHPFGHIPVLETSQCQLIY--ESVIAC---------EYLDDA 96 + I +L K + +PVL + Q I ES E++DD Sbjct: 136 YGYKRISDLYYKSD--PQYSARFTVPVLWDLETQTIVNNESSEIIRILNSSAFDEFVDDD 193 Query: 97 YPGRKLFPYDPYERARQKMLLELFCK-VPHLTKECLVALRCGRECTNLKAALRQEFSNLE 155 + L P A+ K ++ F V + + ++ + F +L+ Sbjct: 194 HKKTDLVP------AQLKTQIDDFNSWVYDSINNGVYKTGFAEKAEVYESEVNNVFEHLD 247 Query: 156 EILEYQNTTF--------------------FGGTCISMIDYLLWPWFERLDVYGI----- 190 ++ + + + G ++ D L+ R D + Sbjct: 248 KVEKILSDKYSKLKAKYGEEDRQKILGEFFTVGDQLTEADIRLYTTVIRFDPVYVQHFKC 307 Query: 191 --LDCVSHTPALRLWISAMKWDPTVCALLMDKSIFQ-GFLNLYFQNNP 235 + P + LW+ + W+ D + + + + NP Sbjct: 308 NFTSIRAGYPFIHLWVRNLYWNYDAFRYTTDFDHIKLHYTRSHTRINP 355 Score = 33.9 bits (76), Expect = 0.071, Method: Composition-based stats. Identities = 10/45 (22%), Positives = 17/45 (37%) Query: 4 DATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIR 48 + R P +G +Y CP++HRT + K + Sbjct: 18 SSFRETISKQHPIYKPAKGRYWLYVSLACPWAHRTLITRALKGLT 62 >4LA1-A nrPDB Length = 602 Score = 36.2 bits (82), Expect = 0.012, Method: Composition-based stats. Identities = 14/71 (19%), Positives = 28/71 (39%), Gaps = 5/71 (7%) Query: 26 IYSMRFCPYSHRTRLVLKAKDIRHEVVNIN-LRNKPEWYYTKHPFGH---IPVLETSQCQ 81 ++S CP+ + + VL I+H + ++ L N F +P + + + Sbjct: 28 VFSKTTCPFCKKLKDVLAEAKIKHATIELDQLSNGSVIQKALSNFSKIETVPQMFV-RGK 86 Query: 82 LIYESVIACEY 92 I +S Y Sbjct: 87 FIGDSKAVLNY 97 >2KLX-A nrPDB Length = 89 Score = 35.9 bits (81), Expect = 0.015, Method: Composition-based stats. Identities = 13/63 (20%), Positives = 25/63 (39%) Query: 17 GPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLE 76 GP I +Y+ CPY R R +L K +++ ++ + + E + P + Sbjct: 1 GPGSMKEIILYTRPNCPYCKRARDLLDKKGVKYTDIDASTSLRQEMVQRANGRNTFPQIF 60 Query: 77 TSQ 79 Sbjct: 61 IGD 63 >3QMX-A nrPDB Length = 99 Score = 35.9 bits (81), Expect = 0.017, Method: Composition-based stats. Identities = 14/65 (21%), Positives = 23/65 (35%), Gaps = 2/65 (3%) Query: 17 GPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGH--IPV 74 G I IY+ CP+ R +LK K + + I+ N+ G +P Sbjct: 11 GSAVSAKIEIYTWSTCPFCMRALALLKRKGVEFQEYCIDGDNEAREAMAARANGKRSLPQ 70 Query: 75 LETSQ 79 + Sbjct: 71 IFIDD 75 >5CAX-A nrPDB Length = 101 Score = 35.1 bits (79), Expect = 0.026, Method: Composition-based stats. Identities = 13/68 (19%), Positives = 26/68 (38%), Gaps = 6/68 (8%) Query: 22 GLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPE------WYYTKHPFGHIPVL 75 G I +Y + C + +T+ +L + E V ++L + E +P P Sbjct: 20 GKIVMYGLSTCVWCKKTKKLLTDLGVDFEYVFVDLLEEEEKSNAIKQVSRFNPSVSFPTT 79 Query: 76 ETSQCQLI 83 + + I Sbjct: 80 ILNDEKAI 87 >1Z7R-A nrPDB Length = 117 Score = 32.4 bits (72), Expect = 0.18, Method: Composition-based stats. Identities = 16/98 (16%), Positives = 35/98 (35%), Gaps = 9/98 (9%) Query: 26 IYSMRFCPYSHRTRLVLKAKDIRHEVVNIN-LRNKPEWYYTK---HPFGHIPVLETSQCQ 81 ++S +C Y +R + +L ++VV ++ L + + G +P + + Sbjct: 25 VFSKTYCGYCNRVKQLLTQVGASYKVVELDELSDGSQLQSALAHWTGRGTVPNVFIG-GK 83 Query: 82 LIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLEL 119 I + + +L P A K +L Sbjct: 84 QIGGCDTVV----EKHQRNELLPLLQDAAATAKNPAQL 117 >4TR1-A nrPDB Length = 92 Score = 32.4 bits (72), Expect = 0.20, Method: Composition-based stats. Identities = 14/57 (24%), Positives = 28/57 (49%), Gaps = 1/57 (1%) Query: 24 IRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP-EWYYTKHPFGHIPVLETSQ 79 I IY+ +CPYS + +L +K + + V++ +K E K + +P + + Sbjct: 4 ITIYTKNYCPYSKKAVSLLSSKGVDFKEVDVTHDSKAFEDVMAKTGWDTVPQVFVDE 60 >5FQ8-B nrPDB Length = 984 Score = 32.0 bits (71), Expect = 0.22, Method: Composition-based stats. Identities = 7/36 (19%), Positives = 16/36 (44%), Gaps = 1/36 (2%) Query: 43 KAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETS 78 + + ++ +N P W+ K+ G P++E Sbjct: 483 NERKVSYQYSEVNDLTIPTWFNLKN-SGKTPIVEQH 517 >1EP3-A nrPDB Length = 311 Score = 32.0 bits (71), Expect = 0.23, Method: Composition-based stats. Identities = 14/67 (20%), Positives = 23/67 (34%), Gaps = 1/67 (1%) Query: 174 IDY-LLWPWFERLDVYGILDCVSHTPALRLWISAMKWDPTVCALLMDKSIFQGFLNLYFQ 232 DY + ++ P ++ A DP V A L+ + LY + Sbjct: 111 ADYVAVCAKIGDAANVKAIELNISCPNVKHGGQAFGTDPEVAAALVKACKAVSKVPLYVK 170 Query: 233 NNPNAFD 239 +PN D Sbjct: 171 LSPNVTD 177 >5JBE-A nrPDB Length = 854 Score = 31.6 bits (70), Expect = 0.34, Method: Composition-based stats. Identities = 10/44 (22%), Positives = 18/44 (40%), Gaps = 2/44 (4%) Query: 201 RLWIS--AMKWDPTVCALLMDKSIFQGFLNLYFQNNPNAFDFGL 242 + W AM W P + + K + F+ + N ++GL Sbjct: 41 KTWYKTTAMDWRPLLMYIWPSKDVQAQFIKYFVNNGYENANYGL 84 >6GFF-A nrPDB Length = 249 Score = 31.2 bits (69), Expect = 0.42, Method: Composition-based stats. Identities = 8/21 (38%), Positives = 14/21 (66%) Query: 11 KGSQPPGPVPEGLIRIYSMRF 31 +G PPGP+PE ++ +Y+ Sbjct: 36 QGEVPPGPLPEAVLALYNSTR 56 >3RJR-A nrPDB Length = 363 Score = 31.2 bits (69), Expect = 0.42, Method: Composition-based stats. Identities = 8/21 (38%), Positives = 14/21 (66%) Query: 11 KGSQPPGPVPEGLIRIYSMRF 31 +G PPGP+PE ++ +Y+ Sbjct: 38 QGDVPPGPLPEAVLALYNSTR 58 >5FFO-C nrPDB Length = 363 Score = 31.2 bits (69), Expect = 0.43, Method: Composition-based stats. Identities = 8/21 (38%), Positives = 14/21 (66%) Query: 11 KGSQPPGPVPEGLIRIYSMRF 31 +G PPGP+PE ++ +Y+ Sbjct: 38 QGEVPPGPLPEAVLALYNSTR 58 >4YUB-A nrPDB Length = 538 Score = 31.2 bits (69), Expect = 0.45, Method: Composition-based stats. Identities = 16/93 (17%), Positives = 30/93 (32%), Gaps = 24/93 (25%) Query: 8 TLGKGSQPPGP---------------VPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVV 52 LG G Q P P +GL+ YS+ + + L ++ + V Sbjct: 256 HLGLGVQEPHPGERAAFVAYALAFPRAFQGLLDTYSVWRSGLPNFLAVALALGELGYRAV 315 Query: 53 NI-----NLRNKPEW----YYTKHPFGHIPVLE 76 + +L + + + +P LE Sbjct: 316 GVRLDSGDLLQQAQEIRKVFRAAAAQFQVPWLE 348 >3IC4-A nrPDB Length = 92 Score = 30.9 bits (68), Expect = 0.52, Method: Composition-based stats. Identities = 13/64 (20%), Positives = 26/64 (40%), Gaps = 6/64 (9%) Query: 26 IYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKP------EWYYTKHPFGHIPVLETSQ 79 +Y + CP+ RT LK + + EV+ I+ E ++ +PV+ Sbjct: 16 MYGLSTCPHCKRTLEFLKREGVDFEVIWIDKLEGEERKKVIEKVHSISGSYSVPVVVKGD 75 Query: 80 CQLI 83 ++ Sbjct: 76 KHVL 79 >1HX8-A nrPDB Length = 299 Score = 30.9 bits (68), Expect = 0.59, Method: Composition-based stats. Identities = 12/82 (14%), Positives = 25/82 (30%), Gaps = 14/82 (17%) Query: 19 VPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINL-----RNKPEWYYTKHPF---G 70 VP G + P+ R L K + + + + + + + Sbjct: 124 VPGGRM---GYDMSPFIRRYAKYLNEKSLSYRAMAFDFCKVKRGKEEGSLRSMNAEKLLK 180 Query: 71 HIPVLETSQCQLI---YESVIA 89 +PVL+ L+ +S Sbjct: 181 TLPVLQAQLDALLEFDCQSNDL 202 >5UE9-A nrPDB Length = 306 Score = 30.9 bits (68), Expect = 0.59, Method: Composition-based stats. Identities = 12/64 (18%), Positives = 22/64 (34%) Query: 176 YLLWPWFERLDVYGILDCVSHTPALRLWISAMKWDPTVCALLMDKSIFQGFLNLYFQNNP 235 + +++ P ++ A DP V A L+ + LY + +P Sbjct: 110 VAVCAKIGDAPNVKVIELNISCPNVKHGGQAFGTDPDVAAALVKACKAVSKVPLYVKLSP 169 Query: 236 NAFD 239 N D Sbjct: 170 NVTD 173 >2MZC-A nrPDB Length = 92 Score = 29.7 bits (65), Expect = 1.3, Method: Composition-based stats. Identities = 12/41 (29%), Positives = 16/41 (39%), Gaps = 2/41 (4%) Query: 26 IYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTK 66 IY+ CPY R + +L K E I+ PE Sbjct: 10 IYTRPGCPYCARAKALLARKGA--EFNEIDASATPELRAEM 48 >2WX2-A nrPDB Length = 473 Score = 29.7 bits (65), Expect = 1.3, Method: Composition-based stats. Identities = 9/68 (13%), Positives = 24/68 (35%), Gaps = 3/68 (4%) Query: 52 VNINLRNKPEWYYTKHPFG---HIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPY 108 V ++R P + + +I S + + ++A+P +L+ + Sbjct: 332 VRESIRRDPPLLMVMRMVKAEVKVGSYVVPKGDIIACSPLLSHHDEEAFPNPRLWDPERD 391 Query: 109 ERARQKML 116 E+ + Sbjct: 392 EKVDGAFI 399 >3LGC-A nrPDB Length = 89 Score = 29.7 bits (65), Expect = 1.3, Method: Composition-based stats. Identities = 10/65 (15%), Positives = 24/65 (36%), Gaps = 8/65 (12%) Query: 23 LIRIYSMRFCPYSHRTRLVLKAKDIRH-EVVNINLRNKPEWYYTKH-------PFGHIPV 74 ++IY+ CPY + + +I E + + + ++Y + P +P Sbjct: 5 KVKIYTRNGCPYCVWAKQWFEENNIAFDETIIDDYAQRSKFYDEMNQSGKVIFPISTVPQ 64 Query: 75 LETSQ 79 + Sbjct: 65 IFIDD 69 >6AZI-A nrPDB Length = 285 Score = 29.3 bits (64), Expect = 1.7, Method: Composition-based stats. Identities = 11/41 (26%), Positives = 14/41 (34%) Query: 182 FERLDVYGILDCVSHTPALRLWISAMKWDPTVCALLMDKSI 222 +D +G + LR WI K P A L K Sbjct: 234 LVVMDAFGKYTHFADASRLRTWIETGKVQPVPAAALTYKKQ 274 >1NM3-A nrPDB Length = 241 Score = 28.9 bits (63), Expect = 1.9, Method: Composition-based stats. Identities = 14/79 (17%), Positives = 27/79 (34%), Gaps = 5/79 (6%) Query: 16 PGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEW--YYTKHPFGHIP 73 P + I I++ CP+ + + +L K + E I L + +P Sbjct: 164 PQHQVQESISIFTKPGCPFCAKAKQLLHDKGLSFE--EIILGHDATIVSVRAVSGRTTVP 221 Query: 74 VLETSQCQLIYESVIACEY 92 + + I S +Y Sbjct: 222 QVFIG-GKHIGGSDDLEKY 239 >3UIW-A nrPDB Length = 154 Score = 28.9 bits (63), Expect = 1.9, Method: Composition-based stats. Identities = 9/33 (27%), Positives = 15/33 (45%) Query: 26 IYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRN 58 I+S CPY + V ++VV ++ N Sbjct: 51 IFSKTTCPYCKMAKGVFNEIGATYKVVELDEHN 83 >1QYC-A nrPDB Length = 308 Score = 28.9 bits (63), Expect = 2.1, Method: Composition-based stats. Identities = 10/54 (18%), Positives = 24/54 (44%), Gaps = 6/54 (11%) Query: 37 RTRLVLKAKDIRHEVVNIN------LRNKPEWYYTKHPFGHIPVLETSQCQLIY 84 + R ++A+ I + V+ N LR+ + T P + +L ++++ Sbjct: 136 KVRRAIEAEGIPYTYVSSNCFAGYFLRSLAQAGLTAPPRDKVVILGDGNARVVF 189 >6MUQ-A nrPDB Length = 283 Score = 28.5 bits (62), Expect = 2.7, Method: Composition-based stats. Identities = 8/31 (25%), Positives = 11/31 (35%) Query: 182 FERLDVYGILDCVSHTPALRLWISAMKWDPT 212 LD +G + LR W+ K P Sbjct: 231 LVVLDAFGKYTHFADANRLRSWMETGKAAPI 261 >3E6I-A nrPDB Length = 476 Score = 27.0 bits (58), Expect = 7.2, Method: Composition-based stats. Identities = 31/162 (19%), Positives = 50/162 (30%), Gaps = 19/162 (11%) Query: 5 ATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYY 64 A +T KG PPGP P + I F L+ K+I + R P + Sbjct: 2 AKKTSSKGKLPPGPFP---LPIIGNLF---------QLELKNIPKSFTRLAQRFGPVFTL 49 Query: 65 TKHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKVP 124 + + + E +Y D+ + GR P R R + Sbjct: 50 YVGSQRMV---VMHGYKAVKE--ALLDYKDE-FSGRGDLPAFHAHRDRGIIFNNGPTWKD 103 Query: 125 HLTKECLVALRCGRECTNLKAALRQEFSNLEEIL-EYQNTTF 165 G ++ +++E L E L + Q F Sbjct: 104 IRRFSLTTLRNYGMGKQGNESRIQREAHFLLEALRKTQGQPF 145 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.129 0.349 Lambda K H 0.267 0.0401 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,365,834 Number of Sequences: 36641 Number of extensions: 355630 Number of successful extensions: 1596 Number of sequences better than 10.0: 166 Number of HSP's better than 10.0 without gapping: 153 Number of HSP's successfully gapped in prelim test: 77 Number of HSP's that attempted gapping in prelim test: 1205 Number of HSP's gapped (non-prelim): 245 length of query: 243 length of database: 10,336,785 effective HSP length: 94 effective length of query: 149 effective length of database: 6,892,531 effective search space: 1026987119 effective search space used: 1026987119 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (20.7 bits) S2: 58 (27.0 bits)