BLASTP 2.2.23 [Feb-03-2010]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Altschul, Stephen F.,
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= Q9H477
(322 letters)
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
36,641 sequences; 10,336,785 total letters
Searching..................................................done
Results from round 1
Score E
Sequences producing significant alignments: (bits) Value
5C40-A nrPDB 663 0.0
5ZWY-A nrPDB 217 4e-57
3RY7-A nrPDB 180 1e-45
1RK2-A nrPDB 163 1e-40
4X8F-A nrPDB 157 4e-39
1VM7-A nrPDB 134 7e-32
6ILS-A nrPDB 120 1e-27
3I3Y-A nrPDB 91 5e-19
6CW5-A nrPDB 78 4e-15
3HJ6-A nrPDB 74 6e-14
1TYY-A nrPDB 71 7e-13
3GBU-A nrPDB 66 2e-11
3GO6-A nrPDB 65 5e-11
3KZH-A nrPDB 64 7e-11
5EYN-A nrPDB 64 7e-11
1V1S-A nrPDB 63 2e-10
3UBO-A nrPDB 62 4e-10
3H49-A nrPDB 59 3e-09
4LC4-A nrPDB 58 5e-09
2NWH-A nrPDB 58 5e-09
2RBC-A nrPDB 58 5e-09
4WJM-A nrPDB 54 8e-08
2QCV-A nrPDB 53 2e-07
2QHP-A nrPDB 53 2e-07
3IQ0-A nrPDB 51 5e-07
2I6B-A nrPDB 50 9e-07
3PL2-A nrPDB 48 6e-06
3LJS-A nrPDB 48 7e-06
2C4E-A nrPDB 47 7e-06
3N1C-A nrPDB 47 1e-05
4DU5-A nrPDB 46 2e-05
3LHX-A nrPDB 46 2e-05
1WYE-A nrPDB 46 2e-05
3LOO-A nrPDB 45 5e-05
2JG5-A nrPDB 44 1e-04
4N08-A nrPDB 42 4e-04
5KB6-A nrPDB 42 4e-04
2HW1-A nrPDB 40 0.001
3UQ9-A nrPDB 39 0.002
3KD6-A nrPDB 39 0.003
2VAR-A nrPDB 39 0.003
3NCA-A nrPDB 39 0.003
3B1N-A nrPDB 37 0.008
1YGJ-A nrPDB 37 0.012
2F7K-A nrPDB 36 0.029
3BF5-A nrPDB 33 0.14
2AFB-A nrPDB 33 0.23
2AWD-A nrPDB 32 0.45
1HKH-A nrPDB 30 1.8
4GM6-A nrPDB 29 2.3
2AA0-A nrPDB 29 3.5
3LUF-A nrPDB 28 4.9
3JUL-A nrPDB 28 6.6
1OXJ-A nrPDB 28 7.2
>5C40-A nrPDB
Length = 330
Score = 663 bits (1710), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 322/322 (100%), Positives = 322/322 (100%)
Query: 1 MAASGEPQRQWQEEVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCV 60
MAASGEPQRQWQEEVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCV
Sbjct: 1 MAASGEPQRQWQEEVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCV 60
Query: 61 QAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNI 120
QAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNI
Sbjct: 61 QAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNI 120
Query: 121 IVIVAGANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAP 180
IVIVAGANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAP
Sbjct: 121 IVIVAGANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAP 180
Query: 181 AIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEG 240
AIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEG
Sbjct: 181 AIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEG 240
Query: 241 CVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAV 300
CVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAV
Sbjct: 241 CVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAV 300
Query: 301 SVQAAGTQSSYPYKKDLPLTLF 322
SVQAAGTQSSYPYKKDLPLTLF
Sbjct: 301 SVQAAGTQSSYPYKKDLPLTLF 322
>5ZWY-A nrPDB
Length = 349
Score = 217 bits (553), Expect = 4e-57, Method: Compositional matrix adjust.
Identities = 132/317 (41%), Positives = 180/317 (56%), Gaps = 15/317 (4%)
Query: 13 EEVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMV 72
E ++VVGSC D V +P+ GET+H F GFGGKGANQ V A RLGA +MV
Sbjct: 33 EYAPDILVVGSCFLDYVGYVDHMPQVGETMHSVSFHKGFGGKGANQAVAAGRLGAKVAMV 92
Query: 73 CKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNE-GQNIIVIVAGANLLL 131
VG D G+DYI+ L++N + T + ++T ++TG A I+V+ + N IVI A
Sbjct: 93 SMVGTDGDGSDYIKELERNGVDTAYMFRTGKSSTGLAMILVDTKSSNNEIVICPNATNHF 152
Query: 132 NTEDLRAAANVISRA-----KVMVCQLEITPATSLEALTMARRSGVKTLFNPAPA----- 181
E LRA N R K ++CQ EI T+L+ + A GV T+FN APA
Sbjct: 153 TPELLRAQTNNYERILHTGLKYLICQNEIPLPTTLDTIKEAHSRGVYTVFNSAPAPKPAE 212
Query: 182 IADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGC 241
+ + P F +FC NE EA ++TG+ V A A L + G + V+ITLGA G
Sbjct: 213 VEQIKP-FLPYVSLFCPNEVEATLITGVKVTDTESAFSAIKALQQLGVRDVVITLGAAG- 270
Query: 242 VVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVS 301
VLS+ EP H+ + VKAVDTTGAGD FVG++ ++++ NL + R+N AA+S
Sbjct: 271 FVLSENGAEPVHVTGKHVKAVDTTGAGDCFVGSMVYFMSRGRNLL--EACKRANECAAIS 328
Query: 302 VQAAGTQSSYPYKKDLP 318
V GTQ SYP+ +LP
Sbjct: 329 VTRKGTQLSYPHPSELP 345
>3RY7-A nrPDB
Length = 304
Score = 180 bits (456), Expect = 1e-45, Method: Compositional matrix adjust.
Identities = 110/296 (37%), Positives = 164/296 (55%), Gaps = 5/296 (1%)
Query: 18 VVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGG-KGANQCVQAARLGAMTSMVCKVG 76
VV++GS D R + GET+H + FGG KGANQ + AR+ A T+ + K+G
Sbjct: 5 VVILGSTNVDQFLTVERYAQPGETLHVEEAQKAFGGGKGANQAIATARMQADTTFITKIG 64
Query: 77 KDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDL 136
D + +E+ K I T + +T +A TG A I VN EGQN I + GAN+ + ED+
Sbjct: 65 TDGVADFILEDFKVAHIDTSYIIKTAEAKTGQAFITVNAEGQNTIYVYGGANMTMTPEDV 124
Query: 137 RAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDPQFYTLSDVF 196
A + I A +V QLE+ + A +A+ GV T+ NPAPA A L + +L D+
Sbjct: 125 INAKDAIINADFVVAQLEVPIPAIISAFEIAKAHGVTTVLNPAPAKA-LPNELLSLIDII 183
Query: 197 CCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPT 256
NE+EAE+L+G+ V + + A L G + V+ITLG +G T+ + +HI
Sbjct: 184 VPNETEAELLSGIKVTNEQSMKDNANYFLSIGIKTVLITLGKQGTYF--ATKNQSQHIEA 241
Query: 257 EKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYP 312
KV A+DTT AGD+F+GA L + +L D ++ N ++++VQ G Q+S P
Sbjct: 242 YKVNAIDTTAAGDTFIGAFVSRLNKSQD-NLADAIDFGNKASSLTVQKHGAQASIP 296
>1RK2-A nrPDB
Length = 309
Score = 163 bits (412), Expect = 1e-40, Method: Compositional matrix adjust.
Identities = 108/305 (35%), Positives = 164/305 (53%), Gaps = 5/305 (1%)
Query: 13 EEVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMV 72
+ ++VV+GS D + P GET+ G+ + + FGGKGANQ V A R GA + +
Sbjct: 2 QNAGSLVVLGSINADHILNLQSFPTPGETVTGNHYQVAFGGKGANQAVAAGRSGANIAFI 61
Query: 73 CKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLN 132
G DS G + L ++I K +TG A I VN EG+N+I I AGAN L+
Sbjct: 62 ACTGDDSIGESVRQQLATDNIDITPVSVIKGESTGVALIFVNGEGENVIGIHAGANAALS 121
Query: 133 TEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDPQFYTL 192
+ A I+ A ++ QLE + + A +A ++ NPAPA +L + L
Sbjct: 122 PALVEAQRERIANASALLMQLESPLESVMAAAKIAHQNKTIVALNPAPA-RELPDELLAL 180
Query: 193 SDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPK 252
D+ NE+EAE LTG+ V + DA +AA VL ++G + V+ITLG+ G V + E +
Sbjct: 181 VDIITPNETEAEKLTGIRVENDEDAAKAAQVLHEKGIRTVLITLGSRG--VWASVNGEGQ 238
Query: 253 HIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYP 312
+P +V+AVDT AGD+F GAL A L + + ++ AA++V G Q S P
Sbjct: 239 RVPGFRVQAVDTIAAGDTFNGAL--ITALLEEKPLPEAIRFAHAAAAIAVTRKGAQPSVP 296
Query: 313 YKKDL 317
+++++
Sbjct: 297 WREEI 301
>4X8F-A nrPDB
Length = 309
Score = 157 bits (398), Expect = 4e-39, Method: Compositional matrix adjust.
Identities = 114/300 (38%), Positives = 162/300 (54%), Gaps = 5/300 (1%)
Query: 18 VVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGK 77
+VV+GS D V P+ GET+HG + + GGKGANQ V AAR+ A + VG
Sbjct: 7 LVVLGSVNADHVLQVPSFPRPGETLHGRNYQVIPGGKGANQAVAAARMQADVGFIACVGD 66
Query: 78 DSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDLR 137
DSFG + E+ K + I+T + TG A I V++ G+N I I A AN L +
Sbjct: 67 DSFGINIRESFKLDGINTAGVKLQPNCPTGIAMIQVSDSGENSICISAEANAKLTAAAIE 126
Query: 138 AAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDPQFYTLSDVFC 197
I A+ ++ QLE L+A A+ + + NPAPA +L + D+
Sbjct: 127 PDLAAIRDARYLLMQLETPLDGILKAAQEAKTAKTNVILNPAPA-RELPDELLKCVDLIT 185
Query: 198 CNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPTE 257
NE+EAE+LTG+TV + A +AA L +G ++VIITLG++G V LSQ + IP
Sbjct: 186 PNETEAEVLTGITVYDDSSAQQAADALHCKGIEIVIITLGSKG-VWLSQNG-RGQRIPGF 243
Query: 258 KVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPYKKDL 317
VKA DTT AGD+F GAL L + LE + ++ AA+SV G Q+S P + ++
Sbjct: 244 VVKATDTTAAGDTFNGALVTGL--LQEMPLESAIKFAHAAAAISVTRFGAQTSIPTRAEV 301
>1VM7-A nrPDB
Length = 311
Score = 134 bits (336), Expect = 7e-32, Method: Compositional matrix adjust.
Identities = 106/301 (35%), Positives = 153/301 (50%), Gaps = 14/301 (4%)
Query: 18 VVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAM-TSMVCKVG 76
+ VVGS D+V K GET + + GGKGANQ V A++G V +G
Sbjct: 17 ISVVGSSNIDIVLKVDHFTKPGETQKAIEMNVFPGGKGANQAVTVAKIGEKGCRFVTCIG 76
Query: 77 KDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDL 136
D + + IEN ++ I+ Y TG A I V+ GQN I+I GAN L E +
Sbjct: 77 NDDYSDLLIENYEKLGITG---YIRVSLPTGRAFIEVDKTGQNRIIIFPGANAELKKELI 133
Query: 137 RAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDPQFYTLSDVF 196
N +S + +++ Q EI T+LE A+R +F+PAPA ++ + + D
Sbjct: 134 DW--NTLSESDILLLQNEIPFETTLEC---AKRFNGIVIFDPAPA-QGINEEIFQYLDYL 187
Query: 197 CCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPT 256
NE E E L+ G +AA L+ G + VI+ LG +G +++++ E KH PT
Sbjct: 188 TPNEKEIEALSKDFFGEFLTVEKAAEKFLELGVKNVIVKLGDKGVLLVNKNEK--KHFPT 245
Query: 257 EKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPYKKD 316
KVKAVDTT AGD F GA A L+ N E+ + AA+SV G QSS P +++
Sbjct: 246 FKVKAVDTTAAGDVFNGAFAVALSEGKN--PEEAVIFGTAAAAISVTRLGAQSSIPAREE 303
Query: 317 L 317
+
Sbjct: 304 V 304
>6ILS-A nrPDB
Length = 313
Score = 120 bits (300), Expect = 1e-27, Method: Compositional matrix adjust.
Identities = 89/307 (28%), Positives = 146/307 (47%), Gaps = 13/307 (4%)
Query: 18 VVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGK 77
+VVVGS D+ RLPK GETI GGKGANQ A+L T V ++G+
Sbjct: 5 LVVVGSANADIYVEIERLPKEGETISAKTGQTLAGGKGANQAACGAKLMYPTYFVGRLGE 64
Query: 78 DSFGNDYIENLKQNDISTEFTY--QTKDAATGTASIIVNNEGQNIIVIVAGANL-----L 130
D+ G E L + Y + TG A +++ ++GQN I+IV GAN+ +
Sbjct: 65 DAHGKLIAEALGDDGCGVHLDYVRSVNNEPTGHAVVMLQSDGQNSIIIVGGANMKAWPEI 124
Query: 131 LNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDPQFY 190
++ +DL ++ A +++ Q EI + +++ +++GV + + + +
Sbjct: 125 MSDDDLE----IVRNAGIVLLQREIPDSINIQVAKAVKKAGVPVILDVGGMDTPIPNELL 180
Query: 191 TLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPE 250
D+ NE+E LTG+ + +A K G + V++ LG++G + Q E
Sbjct: 181 DSIDILSPNETELSRLTGMPTETFEQISQAVAKCHKLGVKQVLVKLGSKGSALFIQGEKP 240
Query: 251 PKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSS 310
+ + VDTTGAGD+F AF +A S E+ L + A++ VQ G S
Sbjct: 241 IQQSIIPAAQVVDTTGAGDTFTA--AFAVAMVEGKSHEECLRFAAAAASLCVQVKGAIPS 298
Query: 311 YPYKKDL 317
P +K +
Sbjct: 299 MPDRKSV 305
>3I3Y-A nrPDB
Length = 299
Score = 91.3 bits (225), Expect = 5e-19, Method: Compositional matrix adjust.
Identities = 84/307 (27%), Positives = 138/307 (44%), Gaps = 36/307 (11%)
Query: 18 VVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGK 77
V V G+ D +PK G +IHG K GGKGANQ + +R G T ++ G
Sbjct: 5 VYVTGNITVDETWSIPDIPKKGASIHGVKVSQDIGGKGANQAIILSRCGIETRLIAATGN 64
Query: 78 DSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQN-IIVIVAGANLLLNTEDL 136
DS G +I +N+ + + T+ I+ + +G N II A A+ E +
Sbjct: 65 DSNGA-WIRQQIKNEPLMLLPDGHFNQHSDTSIILNSADGDNAIITTTAAADTFSLDEMI 123
Query: 137 RAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDPQF---YTLS 193
A+ ++ +++ Q + + AR G+ T+FNP+P ++P F + L
Sbjct: 124 PHMADAVA-GDILLQQGNFSLDKTRALFQYARSRGMTTVFNPSP----VNPDFCHLWPLI 178
Query: 194 DVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKH 253
D+ NESEAE+L G + ++IT GA G ++ E + +
Sbjct: 179 DIAVVNESEAELLQ------------------PYGVKTLVITQGAAGAWLVQ--EGQRQF 218
Query: 254 IPTEKVKAVDTTGAGDSFVGAL---AFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSS 310
P +A+DTTGAGD+F+ + A P+ +R+ I +V GT S+
Sbjct: 219 CPAVPAEALDTTGAGDTFLAVMLASALLRGVAPDALALAHASRAAAI---TVSRRGTLSA 275
Query: 311 YPYKKDL 317
+P ++L
Sbjct: 276 FPGSREL 282
>6CW5-A nrPDB
Length = 332
Score = 78.2 bits (191), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 91/316 (28%), Positives = 133/316 (42%), Gaps = 31/316 (9%)
Query: 19 VVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGKD 78
+V GS D + + GETI GGKGANQ AR G + +G D
Sbjct: 16 LVRGSVNIDEFFHLPHIVRPGETISSTGLTKRAGGKGANQAFAVARAGGQVELDGAIGDD 75
Query: 79 SFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDLRA 138
G E L+ + T+ KD TG A I +G+N IV+ AGAN L +
Sbjct: 76 --GIWVKEMLESAGVGTDKLKIVKDEVTGRAVIQSAADGENSIVLHAGANYYLPSPTPTT 133
Query: 139 AANVISRAKVMVCQLEITPATSLEALTMARRSG--VKTLFNPAPAI--ADLDPQFYTLSD 194
+ + ++ Q E+ +++L LT A +S + ++FNP+P + A L +
Sbjct: 134 SLATYTH---LLVQNEVPLSSTLAYLTAAGQSSPPLTSVFNPSPMLTPAQLREFPWKHLS 190
Query: 195 VFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQV----------------VIITLGA 238
NE E L L GS+A+ GEA L+ +I TLGA
Sbjct: 191 WLIVNEGELGDLL-LAFGSSANPGEAKEDELQAKASAGILELHENDYFSKNVGIICTLGA 249
Query: 239 EGCVVLSQTEPEPKHIPTEKVK--AVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNF 296
+G ++ + E ++P K++ DTTGAGD F G F SL+D L
Sbjct: 250 KG-ILCYEPGKEVGYLPAAKLQNPVKDTTGAGDCFAG--YFVAGLMSGKSLQDALKTCLV 306
Query: 297 IAAVSVQAAGTQSSYP 312
+ V+ G S P
Sbjct: 307 ACGICVENEGAMESVP 322
>3HJ6-A nrPDB
Length = 327
Score = 74.3 bits (181), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 82/315 (26%), Positives = 137/315 (43%), Gaps = 32/315 (10%)
Query: 18 VVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGK 77
VV +G + D++S + ++ FGG AN V +RLG +++ ++G
Sbjct: 24 VVSLGEILVDMISTE----EVNSLSQSREYTRHFGGSPANIAVNLSRLGKKVALISRLGA 79
Query: 78 DSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDLR 137
D+FGN ++ LK I T+ Q K+ T + + + + A++ L +D+
Sbjct: 80 DAFGNYLLDVLKGEQIITDGIQQDKERRTTIVYVSKSTRTPDWLPYRE-ADMYLQEDDI- 137
Query: 138 AAANVISRAKVMVCQ---LEITPA--TSLEALTMARRSGVKTLFNP------APAIAD-- 184
+I R+KV L PA T+++A AR G F+P P D
Sbjct: 138 -IFELIKRSKVFHLSTFILSRKPARDTAIKAFNYAREQGKIVCFDPCYRKVLWPEGDDGA 196
Query: 185 -LDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAAL-VLLKRGCQVVIITLGAEGCV 242
+ + + +D + +A L G D+ E + L+ G + VI+TLG EG
Sbjct: 197 GVVEEIISRADFVKPSLDDARHLFG------PDSPENYVKRYLELGVKAVILTLGEEG-- 248
Query: 243 VLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSV 302
V++ E IP AVD TGAGD+F F +++ + N +AA +
Sbjct: 249 VIASDGEEIIRIPAFSEDAVDVTGAGDAFWS--GFICGLLDGYTVKRSIKLGNGVAAFKI 306
Query: 303 QAAGTQSSYPYKKDL 317
+ G S P K+D+
Sbjct: 307 RGVGALSPVPSKEDI 321
>1TYY-A nrPDB
Length = 339
Score = 70.9 bits (172), Expect = 7e-13, Method: Compositional matrix adjust.
Identities = 78/282 (27%), Positives = 119/282 (42%), Gaps = 24/282 (8%)
Query: 52 GGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASI 111
GG AN V ARLG + +G D G ++ + Q D + T+ DA +A +
Sbjct: 50 GGASANVGVCVARLGGECGFIGCLGDDDAGR-FLRQVFQ-DNGVDVTFLRLDADLTSAVL 107
Query: 112 IVN----NEGQNIIVIVAGANLLLNTEDLRAAANVISRAKVMVCQLEITPATS--LEALT 165
IVN E ++ GA+ ++ +DL L PA LE
Sbjct: 108 IVNLTADGERSFTYLVHPGADTYVSPQDL-PPFRQYEWFYFSSIGLTDRPAREACLEGAR 166
Query: 166 MARRSGVKTLFN-----PAPAIADLDPQFYTLSDVFC--CNESEAEILTGLTVGSAADAG 218
R +G LF+ D P+ S C S E+ + A+
Sbjct: 167 RMREAGGYVLFDVNLRSKMWGNTDEIPELIARSAALASICKVSADELCQ---LSGASHWQ 223
Query: 219 EAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFY 278
+A L GC II+LGA+G +++ T H P +V VDTTGAGD+FVG L F
Sbjct: 224 DARYYLRDLGCDTTIISLGADGALLI--TAEGEFHFPAPRVDVVDTTGAGDAFVGGLLFT 281
Query: 279 LAY---YPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPYKKDL 317
L+ + + L + ++ +N A++V A G ++ P+ L
Sbjct: 282 LSRANCWDHALLAEAISNANACGAMAVTAKGAMTALPFPDQL 323
>3GBU-A nrPDB
Length = 313
Score = 65.9 bits (159), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 75/310 (24%), Positives = 135/310 (43%), Gaps = 35/310 (11%)
Query: 21 VGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGKDSF 80
+G + DL+S+ K H GG AN V +RLG +S++ KVG D F
Sbjct: 7 IGELLIDLISVEEGDLKDVRLFEKHP-----GGAPANVAVGVSRLGVKSSLISKVGNDPF 61
Query: 81 GNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVI--VAGANLLLNTEDLRA 138
G IE L + ++ T + + TG + + + ++ VA N+ LN +
Sbjct: 62 GEYLIEELSKENVDTRGIVKDEKKHTGIVFVQLKGASPSFLLYDDVAYFNMTLNDINW-- 119
Query: 139 AANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDPQFYTLS---DV 195
+++ AK++ + ++ +AR +T+ I + ++ D+
Sbjct: 120 --DIVEEAKIV----------NFGSVILARNPSRETVMKVIKKIKGSSLIAFDVNLRLDL 167
Query: 196 FCCNESEA-EIL-TGLTVGSAADAGEAALVLLK------RGCQVVIITLGAEGCVVLSQT 247
+ E E ++L + + A E ++ L+ +G + ITLG +G ++
Sbjct: 168 WRGQEEEMIKVLEESIKLADIVKASEEEVLYLENQGVEVKGSMLTAITLGPKGFRLIKNE 227
Query: 248 EPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGT 307
+P+ V +DTTGAGD+F+ AL + L L + +N +AA+S Q G
Sbjct: 228 --TVVDVPSYNVNPLDTTGAGDAFMAALLVGILKLKGLDLLKLGKFANLVAALSTQKRGA 285
Query: 308 QSSYPYKKDL 317
S+ P K +L
Sbjct: 286 WST-PRKDEL 294
>3GO6-A nrPDB
Length = 310
Score = 64.7 bits (156), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 83/275 (30%), Positives = 115/275 (41%), Gaps = 29/275 (10%)
Query: 18 VVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGK 77
V VVGS DL + LP+ GET+ GGKGANQ V AAR GA G
Sbjct: 22 VCVVGSVNMDLTFVVDALPRPGETVLAASLTRTPGGKGANQAVAAARAGAQVQFSGAFGD 81
Query: 78 DSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDLR 137
D +L+ N + + T T +GTA I+V+ +N +++ GAN L
Sbjct: 82 DPAAAQLRAHLRANAVGLDRTV-TVPGPSGTAIIVVDASAENTVLVAPGAN-----AHLT 135
Query: 138 AAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDP--QFYTLSDV 195
+ ++ V++ QLEI AT+L A A+ + + N +PA D ++DV
Sbjct: 136 PVPSAVANCDVLLTQLEIPVATALAAARAAQSADAVVMVNASPAGQDRSSLQDLAAIADV 195
Query: 196 FCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIP 255
NE EA + + L RG + V GA+G +P
Sbjct: 196 VIANEHEANDWP-------SPPTHFVITLGVRGARYV----GADGVF----------EVP 234
Query: 256 TEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDM 290
V VDT GAGD F G LA P E +
Sbjct: 235 APTVTPVDTAGAGDVFAGVLAANWPRNPGSPAERL 269
>3KZH-A nrPDB
Length = 328
Score = 64.3 bits (155), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 67/296 (22%), Positives = 126/296 (42%), Gaps = 17/296 (5%)
Query: 18 VVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGK 77
++V G+ + D+ + + + GH I FGG N AR+G T+ + +G
Sbjct: 9 LLVFGASVVDVFGFSKASYRPYNSTPGH-VKISFGGVCRNIAENMARVGVNTNFMSILGN 67
Query: 78 DSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANL-LLNTEDL 136
D G +E+ K+ + + + +T T I++ G+ + I ++ +NT+ +
Sbjct: 68 DEHGKSIVEHSKKIGYHMDDSMVIEGGSTPTYLAILDENGEMVSAIADMKSIGAMNTDFI 127
Query: 137 RAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPA-----IADLDPQFYT 191
+ + A+ V L+ +E L + + +P A + L F+T
Sbjct: 128 DSKREIFENAEYTV--LDSDNPEIMEYLLKNFKDKTNFILDPVSAEKASWVKHLIKDFHT 185
Query: 192 LSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEP 251
+ N EAEIL G + D +A+ L G + V I+L A+G +
Sbjct: 186 IK----PNRHEAEILAGFPITDTDDLIKASNYFLGLGIKKVFISLDADG--IFYNDGVSC 239
Query: 252 KHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGT 307
I +V + TGAGDSFV L + Y + +ED++ + ++ +++ T
Sbjct: 240 GKIKATEVDVKNVTGAGDSFVAGLGY--GYMNKMPIEDIVKFAMTMSNITISHEET 293
>5EYN-A nrPDB
Length = 323
Score = 64.3 bits (155), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 67/291 (23%), Positives = 127/291 (43%), Gaps = 41/291 (14%)
Query: 52 GGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASI 111
GG AN V ARL ++ +VG D FG + L + + + T T +
Sbjct: 44 GGAPANVAVAIARLSGRSAFFGRVGNDPFGRFMQQTLTDEQVDCQHLHFDPVHRTSTVVV 103
Query: 112 IVNNEGQN--IIVIVAGANLLLNTEDLRAAANVISRAKVMVCQLEI----TPATSLEALT 165
++ G+ ++ A+ L D+ + + VC + + + +++ A+
Sbjct: 104 DLDEHGERSFTFMVKPSADQFLQLSDI---PSFQKGEWLHVCSIALANQPSRSSTFAAIA 160
Query: 166 MARRSGVKTLFNPAPAIADLDPQFYT--------------LSDVFCCNESEAEILTGLTV 211
+ G F+P +L + ++ L+DV +E E + LTG
Sbjct: 161 QMKEVGGYVSFDP-----NLREEVWSEPQELQATVMRAVGLADVVKFSEEELQFLTGT-- 213
Query: 212 GSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPTEK-VKAVDTTGAGDS 270
+ + G A+ + +V++TLGA+G +V + P + I + K VK +DTTGAGD+
Sbjct: 214 -QSIEEGLQAIADFQ--IPLVVVTLGAKGALVAT---PNSQQIVSGKAVKPIDTTGAGDA 267
Query: 271 FVGALAFYLA----YYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPYKKDL 317
FVG L + L+ ++ ++ D + +N A++ G ++ P + L
Sbjct: 268 FVGGLLYRLSVAQDWHNQATILDAVKWANGCGALATTQKGAMTALPNQAAL 318
>1V1S-A nrPDB
Length = 309
Score = 62.8 bits (151), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 87/324 (26%), Positives = 126/324 (38%), Gaps = 46/324 (14%)
Query: 18 VVVVGSCMTDLVSLTSRLPKTGETIHGHKFF-IGFGGKGANQCVQAARLGAMTSMVCKVG 76
VV G + LV P+ + G + + GG N V ARLG V +VG
Sbjct: 4 VVTAGEPLVALV------PQEPGHLRGKRLLEVYVGGAEVNVAVALARLGVKVGFVGRVG 57
Query: 77 KDSFGNDYIENLKQNDIS-TEFT--------YQTKDAATGTASIIVNNEGQNIIVIVAGA 127
+D G E L+ + T F Y + G + +G + GA
Sbjct: 58 EDELGAMVEERLRAEGVDLTHFRRAPGFTGLYLREYLPLGQGRVFYYRKGSAGSALAPGA 117
Query: 128 NLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVK---------TLFNP 178
D + + + A SL A+ A+R GV+ TL++P
Sbjct: 118 F----DPDYLEGVRFLHLSGITPALSPEARAFSLWAMEEAKRRGVRVSLDVNYRQTLWSP 173
Query: 179 APAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGA 238
A L+ + D+ +E EAE+L G V A A A V+LKRG + GA
Sbjct: 174 EEARGFLERALPGV-DLLFLSEEEAELLFG-RVEEALRALSAPEVVLKRGAK------GA 225
Query: 239 EGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLA-YYPNLSLEDMLNRSNFI 297
V + E V+AVD GAGD+F A YLA L +E+ L +N +
Sbjct: 226 WAFVDGRRVEGS-----AFAVEAVDPVGAGDAFA---AGYLAGAVWGLPVEERLRLANLL 277
Query: 298 AAVSVQAAGTQSSYPYKKDLPLTL 321
A + G PY++DL + L
Sbjct: 278 GASVAASRGDHEGAPYREDLEVLL 301
>3UBO-A nrPDB
Length = 354
Score = 61.6 bits (148), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 73/277 (26%), Positives = 113/277 (40%), Gaps = 39/277 (14%)
Query: 52 GGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTK----DAATG 107
GG N A LG + KV D G + +++ + +QTK T
Sbjct: 60 GGSAGNTAAGVASLGGRAAYFGKVADDQLGEIFTHDIRAQGVH----FQTKPLDGHPPTA 115
Query: 108 TASIIVNNEGQNIIVIVAGANLLLNTEDLRAAANVISRAKVMVCQLEI-TPATSLEALTM 166
+ I V +G+ + GA + L ED+ +V++++KV + + P + +A+
Sbjct: 116 RSMIFVTEDGERSMNTYLGACVELGPEDVED--DVVAQSKVTYFEGYLWDPPRAKDAIRE 173
Query: 167 ARRSGVKTLFNPAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSA----ADAGEA-- 220
A R A A TLSD FC + +E L + G+ A+ EA
Sbjct: 174 AARI----------AHAHGRETAMTLSDSFCVHRYRSEFLELMRSGTVDIVFANRQEALA 223
Query: 221 ---------ALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSF 271
AL LL R C++ +TL EG VV+ E + + + VDTTGAGD +
Sbjct: 224 LYETEDFDRALELLARDCKLAAVTLSEEGSVVVRGAE-RVRVGASVLEQVVDTTGAGDLY 282
Query: 272 VGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQ 308
A F Y SLE+ N A + + G +
Sbjct: 283 --AAGFLFGYTSGRSLEECSKLGNLAAGIVIGQIGPR 317
>3H49-A nrPDB
Length = 325
Score = 58.9 bits (141), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 72/275 (26%), Positives = 125/275 (45%), Gaps = 22/275 (8%)
Query: 52 GGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASI 111
GG N+ +RLG T+++ ++GKD+ G +++ ++ +I + Q T
Sbjct: 43 GGDAINEATIISRLGHRTALMSRIGKDAAGQFILDHCRKENIDIQSLKQDVSIDTSINVG 102
Query: 112 IVNNEGQNIIVIVAGANLL-LNTEDLRAAANVISRAKVM-VCQLEITPATSLEALT-MAR 168
+V +G+ V +L LN +D+ A S+AK++ + + +P +ALT +
Sbjct: 103 LVTEDGERTFVTNRNGSLWKLNIDDVDFAR--FSQAKLLSLASIFNSPLLDGKALTEIFT 160
Query: 169 RSGVKTLFNPAPAIA-----DLDPQFYTLS--DVFCCNESEAEILTGL-TVGSAADAGEA 220
++ + + A I LD LS D N +EA++LTG T+ AD
Sbjct: 161 QAKARQMIICADMIKPRLNETLDDICEALSYVDYLFPNFAEAKLLTGKETLDEIADC--- 217
Query: 221 ALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLA 280
L G + V+I G +GC + + + K + A+DT GAGD+F A F A
Sbjct: 218 ---FLACGVKTVVIKTGKDGCFI-KRGDMTMKVPAVAGITAIDTIGAGDNF--ASGFIAA 271
Query: 281 YYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPYKK 315
+L + +N AA+SV + G + +K
Sbjct: 272 LLEGKNLRECARFANATAAISVLSVGATTGVKNRK 306
>4LC4-A nrPDB
Length = 352
Score = 58.2 bits (139), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 70/282 (24%), Positives = 109/282 (38%), Gaps = 49/282 (17%)
Query: 52 GGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAA----TG 107
GG N A LG + V D G+ + +++ + YQTK T
Sbjct: 80 GGSAGNTAAGVANLGGKAAYFGNVAADQLGDIFTHDIRAQGVH----YQTKPKGAFPPTA 135
Query: 108 TASIIVNNEGQNIIVIVAGANLLLNTEDLRAAANVISRAKVMVCQLEI-TPATSLEAL-- 164
+ I V +G+ + GA + L ED+ A +V++ AKV + + P + EA+
Sbjct: 136 RSMIFVTEDGERSMNTYLGACVELGPEDVEA--DVVADAKVTYFEGYLWDPPRAKEAILD 193
Query: 165 --TMARRSGVKTLFNPAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSA-------- 214
+A + G + TLSD FC + E L + G
Sbjct: 194 CARIAHQHGREMSM--------------TLSDSFCVDRYRGEFLDLMRSGKVDIVFANRQ 239
Query: 215 -------ADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPTEKVK-AVDTTG 266
D E AL + C++ +T+ G V+L E ++ +++ VDTTG
Sbjct: 240 EALSLYQTDDFEEALNRIAADCKIAAVTMSENGAVILKGRER--YYVNAIRIREVVDTTG 297
Query: 267 AGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQ 308
AGD F A F Y SLED A + +Q G +
Sbjct: 298 AGDLF--ASGFLYGYTQGRSLEDCGKLGCLAAGIVIQQIGPR 337
>2NWH-A nrPDB
Length = 317
Score = 58.2 bits (139), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 79/276 (28%), Positives = 122/276 (44%), Gaps = 28/276 (10%)
Query: 52 GGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDI-STEFTYQTKDAATGTAS 110
GG G N +RLG ++ G D G E +Q + T FT+ + + TA
Sbjct: 39 GGGGFNAARNLSRLGFEVRIIAPRGGDVTGEVVAEAARQAGVEDTPFTFLDRRTPSYTA- 97
Query: 111 IIVNNEGQNIIVIVAGANL--LLNTEDL--RAAANVISRAKVMVCQLEITPATSLEALTM 166
I+ +G N+++ +A +L L L RA I + ++C + P +L AL +
Sbjct: 98 -ILERDG-NLVIALADMDLYKLFTPRRLKVRAVREAIIASDFLLCDANL-PEDTLTALGL 154
Query: 167 ARRSGVKTL----FNPAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAAL 222
R+ K L +PA A+ L + D+ NE+EA LTG T + D
Sbjct: 155 IARACEKPLAAIAISPAKAV-KLKAALGDI-DILFMNEAEARALTGETAENVRDWPN--- 209
Query: 223 VLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIP-TEKVKAVDTTGAGDSFVGALAFYLAY 281
+L K G ++T GA V + TE H P +VK D TGAGD+ A + A
Sbjct: 210 ILRKAGLSGGVVTRGASEVVAFNGTEKAILHPPLIREVK--DVTGAGDAM--ASGYLAAI 265
Query: 282 YPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPYKKDL 317
++ + L + AA++V QSS+ +DL
Sbjct: 266 AEGKTIREALRQGAAAAAITV-----QSSFATSQDL 296
>2RBC-A nrPDB
Length = 343
Score = 58.2 bits (139), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 70/269 (26%), Positives = 112/269 (41%), Gaps = 19/269 (7%)
Query: 18 VVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGK 77
V+ VG+ + D + + +PK + ++ G ++ R+G S+ VG
Sbjct: 32 VLCVGAAVLDTLFRVADMPKGEGKVLPYEVLQIAEGMASSAAYAVHRMGGRASLWGAVGD 91
Query: 78 DSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDLR 137
D G + +L ++ I T A + ++II++N G+ +IV L E R
Sbjct: 92 DETGTRILRDLSESGIDTSGMTVAPGARSALSTIIIDNRGERLIVPFYDHRL---HEKKR 148
Query: 138 A-AANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFN----PAPAIADLDPQFYTL 192
A I+ ++ + P +L+ LT+AR G + + P + L P +
Sbjct: 149 ACTPEDIALFDAVLVDVRW-PELALDVLTVARALGKPAILDGDVAPVETLEGLAPAATHI 207
Query: 193 SDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVI-ITLGAEGCVVLSQTEPEP 251
VF +E A LTGL + VL R Q I +T G GC +P
Sbjct: 208 --VF--SEPAATRLTGLET-----VKDMLPVLHARYPQTFIAVTAGPAGCWWTEADDPTV 258
Query: 252 KHIPTEKVKAVDTTGAGDSFVGALAFYLA 280
T +V+AVDT AGD F G A +A
Sbjct: 259 HFQTTMQVEAVDTLAAGDIFHGTFALAMA 287
>4WJM-A nrPDB
Length = 312
Score = 53.9 bits (128), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 62/260 (23%), Positives = 98/260 (37%), Gaps = 36/260 (13%)
Query: 30 SLTSRLPKTGETIHGHKFFIGF-GGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENL 88
+L LP+ ET G F F GG N + RLG T + D FG+ + L
Sbjct: 14 ALIDMLPR--ETTGGETAFQPFAGGSVFNTAIALGRLGVPTGFFSGISSDFFGDVLRDTL 71
Query: 89 KQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDLRAAANVISRAKV 148
++++ F + T +V+ + + A +L+ D+ IS
Sbjct: 72 ARSNVDYSFAAISNRPTTLAFVRLVDGQARYAFYDENTAGRMLSRNDMPYVDETISAMLF 131
Query: 149 MVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDP------------------QFY 190
L P S+ +AR + + +F LDP +
Sbjct: 132 GCISLISEPCGSVYETLLAREAPNRVMF--------LDPNIRANLITVRKTHLTRMKRMI 183
Query: 191 TLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPE 250
L+D+ ++ + + G E A LK G ++V+IT GA G V +
Sbjct: 184 ALADIVKLSDEDLDWF-----GEKGSHDEIAAEWLKLGPKLVVITKGAHGAVAYTNHATV 238
Query: 251 PKHIPTEKVKAVDTTGAGDS 270
P +P KV VDT GAGD+
Sbjct: 239 P--VPGVKVDVVDTVGAGDT 256
>2QCV-A nrPDB
Length = 332
Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 66/292 (22%), Positives = 122/292 (41%), Gaps = 52/292 (17%)
Query: 18 VVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGK 77
++ +G DL ++ P ET+ K+ GG AN + +++LG + K+
Sbjct: 14 LIAIGRACIDLNAVEYNRPME-ETMTFSKYV---GGSPANIVIGSSKLGLKAGFIGKIAD 69
Query: 78 DSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQN----------------II 121
D G +IE+ + T++++V+ EG ++
Sbjct: 70 DQHGR-FIESY------------MRGVGVDTSNLVVDQEGHKTGLAFTEIKSPEECSILM 116
Query: 122 VIVAGANLLLNTEDLRAAANVISRAKVMVCQ---LEITPATS--LEALTMARRSGVKTLF 176
A+L L+ E++ A I R+K+++ L +P+ L+A+ +A+R+ VK +F
Sbjct: 117 YRQDVADLYLSPEEVNEA--YIRRSKLLLVSGTALSKSPSREAVLKAIRLAKRNDVKVVF 174
Query: 177 --NPAPAIADLDPQ---FYTL----SDVFCCNESEAEILTGLTVGSAADAGEAALVLLKR 227
+ P + + +Y+L SD+ E ++L T D E L K
Sbjct: 175 ELDYRPYSWETPEETAVYYSLVAEQSDIVIGTREEFDVLENRT--EKGDNDETIRYLFKH 232
Query: 228 GCQVVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYL 279
++++I G EG ++ E K K + T GAGDS+ A + L
Sbjct: 233 SPELIVIKHGVEGSFAYTKA-GEAYRGYAYKTKVLKTFGAGDSYASAFLYAL 283
>2QHP-A nrPDB
Length = 296
Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 65/244 (26%), Positives = 102/244 (41%), Gaps = 34/244 (13%)
Query: 52 GGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASI 111
GG AN ++ G + +V VG D G++ +E K+ + + + D TGT +
Sbjct: 24 GGAPANFAYHVSQFGFDSRVVSAVGNDELGDEIMEVFKEKQLKNQI--ERVDYPTGTVQV 81
Query: 112 IVNNEGQNIIVI---VAGANLLLNTEDLRAAANVISRAKVMVC------QLEITPATSLE 162
+++EG I VA N+ E R A N +RA VC + E++ AT
Sbjct: 82 TLDDEGVPCYEIKEGVAWDNIPFTDELKRLALN--TRA---VCFGSLAQRNEVSRATINR 136
Query: 163 AL-TMARRSGVKTLFNPAPAIADLDPQFYTLS---------DVFCCNESEAEILTGLTVG 212
L TM G +F+ +L FYT ++ N+ E ++ +
Sbjct: 137 FLDTMPDIDGQLKIFD-----INLRQDFYTKEVLRESFKRCNILKINDEELVTISRMFGY 191
Query: 213 SAADAGEAALVLL-KRGCQVVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSF 271
D + +LL K +++I+T G G V + + P KV DT GAGDSF
Sbjct: 192 PGIDLQDKCWILLAKYNLKMLILTCGINGSYVFTPGVVSFQETP--KVPVADTVGAGDSF 249
Query: 272 VGAL 275
A
Sbjct: 250 TAAF 253
>3IQ0-A nrPDB
Length = 330
Score = 51.2 bits (121), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 57/235 (24%), Positives = 95/235 (40%), Gaps = 36/235 (15%)
Query: 61 QAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNI 120
Q RLG ++ VG D FG+ I L + + ATG+A + +N G
Sbjct: 46 QVTRLGVPCGIISCVGNDGFGDINIHRLAADGVDIRGISVLPLEATGSAFVTYHNSGDR- 104
Query: 121 IVIVAGANLLLNTEDL---RAAANVISRAKVMVCQLEITPATSL----------EALTMA 167
+ + N ++ + +A + + C +SL +A+T+
Sbjct: 105 -------DFIFNIKNAACGKLSAQHVDENILKDCTHFHIMGSSLFSFHMVDAVKKAVTIV 157
Query: 168 RRSGVKTLFNP--------APAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGE 219
+ +G F+P P + D L+D++ +E E +L+ + A AG
Sbjct: 158 KANGGVISFDPNIRKEMLDIPEMRDALHFVLELTDIYMPSEGEVLLLSPHSTPERAIAG- 216
Query: 220 AALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGA 274
L+ G + VI+ G +G S E H+ + V+ VD TGAGD F GA
Sbjct: 217 ----FLEEGVKEVIVKRGNQGASYYSANEQ--FHVESYPVEEVDPTGAGDCFGGA 265
>2I6B-A nrPDB
Length = 345
Score = 50.4 bits (119), Expect = 9e-07, Method: Compositional matrix adjust.
Identities = 60/264 (22%), Positives = 110/264 (41%), Gaps = 30/264 (11%)
Query: 75 VGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTE 134
+G D FG + + + Y+ + TGT + + + +++I +A AN +
Sbjct: 90 IGIDKFGEILKRKAAEAHVDAHY-YEQNEQPTGTCAACITGDNRSLIANLAAANCYKKEK 148
Query: 135 DLRAAANVISRAKVMVCQ-----LEITPATSLEALTMARRSG-VKTLFNPAPAIADLDPQ 188
L N + K VC L ++P + L+ A + + TL AP I+ Q
Sbjct: 149 HLDLEKNWMLVEKARVCYIAGFFLTVSPESVLKVAHHASENNRIFTLNLSAPFIS----Q 204
Query: 189 FYTLS--------DVFCCNESEAEILT---GLTVGSAADAGEAALVLLK---RGCQVVII 234
FY S D+ NE+EA G + + L K + ++VI
Sbjct: 205 FYKESLMKVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKTQALPKMNSKRQRIVIF 264
Query: 235 TLGAEGCVVLSQTEPEPKHIPTEKVKAV-DTTGAGDSFVGALAFYLAYYPNLSLEDMLNR 293
T G + ++ +++E + + K + DT GAGD+FVG F + L + +
Sbjct: 265 TQGRDDTIMATESEVTAFAVLDQDQKEIIDTNGAGDAFVG--GFLSQLVSDKPLTECIRA 322
Query: 294 SNFIAAVSVQAAGTQSSYPYKKDL 317
++ A++ ++ G ++P K D
Sbjct: 323 GHYAASIIIRRTG--CTFPEKPDF 344
>3PL2-A nrPDB
Length = 319
Score = 48.1 bits (113), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 72/272 (26%), Positives = 114/272 (41%), Gaps = 39/272 (14%)
Query: 51 FGGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEF--TYQTKDAATGT 108
GG AN V AAR G ++++ +VG D FG + L++ + ++ T QT
Sbjct: 40 LGGSAANVSVAAARHGHNSALLSRVGNDPFGEYLLAELERLGVDNQYVATDQTFKTPVTF 99
Query: 109 ASIIVNNEGQNIIVIVAGANLLLNTEDLRAAANVISRAKVMVCQL-----EITPATSLEA 163
I ++ A L N E + + + A ++ L E + T E
Sbjct: 100 CEIFPPDDFPLYFYREPKAPDL-NIESADVSLDDVREADILWFTLTGFSEEPSRGTHREI 158
Query: 164 LTMARRSGVKTLFNPAPAIADLDPQFY--------------TLSDVFCCNESEAEILTGL 209
LT R + T+F+ D P F+ S V N+ E EI G
Sbjct: 159 LT-TRANRRHTIFD-----LDYRPMFWESPEEATKQAEWALQHSTVAVGNKEECEIAVGE 212
Query: 210 TVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGD 269
T + A LL+RG ++ I+ G +G V++ T+ E +P V ++ GAGD
Sbjct: 213 T-----EPERAGRALLERGVELAIVKQGPKG--VMAMTKDETVEVPPFFVDVINGLGAGD 265
Query: 270 SFVGALAF-YLAYYPNLSLEDMLNRSNFIAAV 300
+F GAL L+ +P LE +L +N A+
Sbjct: 266 AFGGALCHGLLSEWP---LEKVLRFANTAGAL 294
>3LJS-A nrPDB
Length = 338
Score = 47.8 bits (112), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 63/249 (25%), Positives = 102/249 (40%), Gaps = 31/249 (12%)
Query: 52 GGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASI 111
GG AN V ARLG V +G D FG+ ++ + + T+ +T A T A +
Sbjct: 36 GGAPANVAVAVARLGGAVQFVGMLGSDMFGDFLFDSFAEAGVVTDGIVRTSTAKTALAFV 95
Query: 112 IVNNEGQNIIVIV--AGANLLLNTEDLRAAANVISRAKVM-VCQLEITPA----TSLEAL 164
++ G+ A+LL E + A+ S A + C +T A + E +
Sbjct: 96 ALDAHGERSFSFYRPPAADLLFRVEHFQDAS--FSDALIFHACSNSMTDADIAEVTFEGM 153
Query: 165 TMARRSGVKTLF-------------NPAPAIADLDPQFYTLSDVFCCNESEAEILTGLTV 211
A+ +G F NPA + + +L+DV + E + L
Sbjct: 154 RRAQAAGAIVSFDLNFRPMLWPNGENPASRLW----KGLSLADVVKLSSEELDYLANTL- 208
Query: 212 GSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSF 271
AADA L + Q++++T A V T +PT +V+ D+ AGD+F
Sbjct: 209 --AADANAVIQQLWQGRAQLLLVTDAA--GPVHWYTRTAGGEVPTFRVQVQDSNAAGDAF 264
Query: 272 VGALAFYLA 280
VG + + A
Sbjct: 265 VGGMLYTFA 273
>2C4E-A nrPDB
Length = 302
Score = 47.4 bits (111), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 71/312 (22%), Positives = 118/312 (37%), Gaps = 40/312 (12%)
Query: 14 EVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVC 73
++ + VG D + + P+ +I +GG AN V +LG + ++
Sbjct: 4 KMEKITCVGHTALDYIFNVEKFPEPNTSIQIPSARKYYGGAAANTAVGIKKLGVNSELLS 63
Query: 74 KVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLL--- 130
VG D + Y LK DI+ Y +++ T A I + + I + GA
Sbjct: 64 CVGYDFKNSGYERYLKNLDINISKLYYSEEEETPKAWIFTDKDNNQITFFLWGAAKHYKE 123
Query: 131 -----LNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADL 185
NTE + A P +L+ A + + + F+P +
Sbjct: 124 LNPPNFNTEIVHIATG--------------DPEFNLKCAKKAYGNNLVS-FDPGQDLPQY 168
Query: 186 DPQFY----TLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGC 241
+ ++ N+ E E + L D L+R +I+T G++G
Sbjct: 169 SKEMLLEIIEHTNFLFMNKHEFERASNLLNFEIDD-------YLER-VDALIVTKGSKGS 220
Query: 242 VVLSQTEPEPKHIPTEKV-KAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAV 300
V+ T+ + IP K K +D TGAGDS+ F AY LE A+
Sbjct: 221 VIY--TKDKKIEIPCIKAGKVIDPTGAGDSYRA--GFLSAYVKGYDLEKCGLIGAATASF 276
Query: 301 SVQAAGTQSSYP 312
V+A G Q++ P
Sbjct: 277 VVEAKGCQTNLP 288
>3N1C-A nrPDB
Length = 309
Score = 47.0 bits (110), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 64/261 (24%), Positives = 106/261 (40%), Gaps = 41/261 (15%)
Query: 52 GGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASI 111
GG G N A LG + + G + G + L ++ T + KD +
Sbjct: 38 GGGGINVARAIAHLGGSATAIFPAG-GATGEHLVSLLADENVPVA-TVEAKDWTRQNLHV 95
Query: 112 IVNNEGQNIIVIVAGANLLLNTEDLRAAANV---ISRAKVMVCQLEITPATSLEALTM-- 166
V G+ ++ GA LN ++ R I ++V + P LE LT
Sbjct: 96 HVEASGEQYRFVMPGA--ALNEDEFRQLEEQVLEIESGAILVISGSLPPGVKLEKLTQLI 153
Query: 167 --ARRSGVKTL-------FNPAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADA 217
A++ G++ + + A AI +++ + N+ E L + D
Sbjct: 154 SAAQKQGIRCIVDSSGEALSAALAIGNIE--------LVKPNQKELSALVNRELTQPDDV 205
Query: 218 GEAALVLLKRG-CQVVIITLGAEGCVVLS-----QTEPEPKHIPTEKVKAVDTTGAGDSF 271
+AA ++ G + V+++LG +G + + Q P P VK+ T GAGDS
Sbjct: 206 RKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQVVPPP-------VKSQSTVGAGDSM 258
Query: 272 VGALAFYLAYYPNLSLEDMLN 292
VGA+ LA N SLE+M+
Sbjct: 259 VGAMTLKLAE--NASLEEMVR 277
>4DU5-A nrPDB
Length = 336
Score = 46.2 bits (108), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 73/330 (22%), Positives = 113/330 (34%), Gaps = 57/330 (17%)
Query: 18 VVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGK 77
V+ G M LV+ + G H F G N + ARLG ++G
Sbjct: 29 VITFGEAMMLLVA-----DRPGPLEHAEAFHKRTAGAETNVAIGLARLGLKVGWASRLGT 83
Query: 78 DSFGNDYIENLKQNDIS-----------TEFTYQTKDAATGTASIIVNNEGQNIIVIVAG 126
DS G + + I T F ++ K + + +G
Sbjct: 84 DSMGRYLLAAMAAEGIDCSHVVCDATQKTGFQFKGKVTDGSDPPVEYHRKGS-------- 135
Query: 127 ANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEA----LTMARRSGVKTLFNPAPAI 182
A + D+ A + +R AT+L A + + R +G F+P
Sbjct: 136 AASHMGVADIDEAWLLSARHLHATGVFPAISATTLPAARKTMDLMRAAGRSVSFDP---- 191
Query: 183 ADLDPQFY--------------TLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRG 228
+L P + T +D E LTG T A + G
Sbjct: 192 -NLRPTLWATPELMRDAINDLATRADWVLPGMEEGRFLTGETTPEGV-----ARFYRQLG 245
Query: 229 CQVVIITLGAEGCVVLSQT-EPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSL 287
++V++ LGAEG + P +V VDT GAGD F A+ A L +
Sbjct: 246 AKLVVVKLGAEGAYFDGEAGSGRVAGFPVAEV--VDTVGAGDGF--AVGVISALLDGLGV 301
Query: 288 EDMLNRSNFIAAVSVQAAGTQSSYPYKKDL 317
+ + R +I A +VQ G P + +L
Sbjct: 302 PEAVKRGAWIGARAVQVLGDSEGLPTRAEL 331
>3LHX-A nrPDB
Length = 319
Score = 46.2 bits (108), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 78/318 (24%), Positives = 122/318 (38%), Gaps = 52/318 (16%)
Query: 18 VVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARL---GAMT-SMVC 73
+ V+G CM +L + + + GFGG N V AR A+T V
Sbjct: 7 IAVIGECMIELSEKGADVKR------------GFGGDTLNTSVYIARQVDPAALTVHYVT 54
Query: 74 KVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIV---AGANLL 130
+G DSF ++ ++ T T + ++ G I ++ G+ A A
Sbjct: 55 ALGTDSFSQQMLDAWHGENVDTSLTQRMENRLPGLYYIETDSTGERTFYYWRNEAAAKFW 114
Query: 131 LNTEDLRAAANVISRAKVMV---CQLEITPATSLEAL----TMARRSGVKTLF--NPAPA 181
L +E A ++ + L I TS E L R G K +F N P
Sbjct: 115 LASEQSAAICEELANFDYLYLSGISLAILSPTSREKLLSLLRECRAKGGKVIFDNNYRPR 174
Query: 182 I-------ADLDPQFYTLSDVFCCNESEAEILTGL-----TVGSAADAGEAALVLLKRGC 229
+ + Q +D+ + + L G + +AG V++KRG
Sbjct: 175 LWASKEETQQVYQQMLECTDIAFLTLDDEDALWGQQPVEDVIARTHNAG-VKEVVVKRGA 233
Query: 230 QVVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSF-VGALAFYLAYYPNLSLE 288
++++ E V + P K +P EKV +DTT AGDSF G LA L S E
Sbjct: 234 DSCLVSIAGEALVDV----PAVK-LPKEKV--IDTTAAGDSFSAGYLAVRLT---GGSAE 283
Query: 289 DMLNRSNFIAAVSVQAAG 306
+ R + A+ +Q G
Sbjct: 284 NAAKRGHLTASTVIQYRG 301
>1WYE-A nrPDB
Length = 311
Score = 45.8 bits (107), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 69/322 (21%), Positives = 126/322 (39%), Gaps = 39/322 (12%)
Query: 15 VAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCK 74
+A ++ +G + + +L+ G H F G AN CV + G ++ K
Sbjct: 1 MAKLITLGEILIEFNALS-----PGPLRHVSYFEKHVAGSEANYCVAFIKQGNECGIIAK 55
Query: 75 VGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASII----VNNEGQNIIVIVAGANLL 130
VG D FG + IE L+ + A TG I V + ++I A
Sbjct: 56 VGDDEFGYNAIEWLRGQGVDVSHMKIDPSAPTGIFFIQRHYPVPLKSESIYYRKGSAGSK 115
Query: 131 LNTEDLR----AAANVISRAKVMVCQLEITPATSLEALTMARRSGVKT-----LFNPAPA 181
L+ ED+ +A+++ + + + +A +A T L++ A
Sbjct: 116 LSPEDVDEEYVKSADLVHSSGITLAISSTAKEAVYKAFEIASNRSFDTNIRLKLWSAEEA 175
Query: 182 ---IADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGA 238
I L +F+ + +++I+ G +D +AA +++++ LG
Sbjct: 176 KREILKLLSKFHL--KFLITDTDDSKIILG-----ESDPDKAAKAFSDY-AEIIVMKLGP 227
Query: 239 EGCVVL---SQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSN 295
+G +V + +P E D TGAGD+ G F YY +E L+ +
Sbjct: 228 KGAIVYYDGKKYYSSGYQVPVE-----DVTGAGDALGGT--FLSLYYKGFEMEKALDYAI 280
Query: 296 FIAAVSVQAAGTQSSYPYKKDL 317
+ ++V G Q + P KD+
Sbjct: 281 VASTLNVMIRGDQENLPTTKDI 302
>3LOO-A nrPDB
Length = 365
Score = 44.7 bits (104), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 57/223 (25%), Positives = 96/223 (43%), Gaps = 27/223 (12%)
Query: 75 VGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTE 134
VG+D + E N ++ ++ ++ + TGT +++V +++ +A AN E
Sbjct: 106 VGQDEYARILEERATSNGVNVQYQ-RSATSPTGTCAVLVTGTQRSLCANLAAANDF-TPE 163
Query: 135 DLRAAANVISRAKVMVCQLEITPA----TSLE-ALTMARRSGVKTLFNPAPAIADLDPQF 189
LR+ N RA + Q S E AL++A+ + A PQF
Sbjct: 164 HLRSDGN---RAYLQGAQFFYVSGFFFTVSFESALSVAKEAAATGRMFMMNLSAPFVPQF 220
Query: 190 YT--------LSDVFCCNESEAEILTG-LTVGSA--ADAGEAALVLLK---RGCQVVIIT 235
Y DV NE+EA L G+ + G+ L K + ++VIIT
Sbjct: 221 YKNNLEEIFPYVDVLFGNETEAIALAKEFNYGTEDLREIGKRIAALPKENGKRKRIVIIT 280
Query: 236 LGAEGCVVLSQTEPEPKHIPTEKV---KAVDTTGAGDSFVGAL 275
G++ +++ + P +K+ + VDT GAGD+FVG
Sbjct: 281 QGSDPVLLIEAGTDNVREFPVQKLAPEQMVDTNGAGDAFVGGF 323
>2JG5-A nrPDB
Length = 306
Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 31/100 (31%), Positives = 51/100 (51%), Gaps = 12/100 (12%)
Query: 199 NESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPTEK 258
N+ E E++ TV S AD + +L+ +G Q VI++LG +G + + K I +
Sbjct: 181 NKDELEVMFNTTVNSDADVIKYGRLLVDKGAQSVIVSLGGDGAIYID------KEISIKA 234
Query: 259 V----KAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRS 294
V K V+T G+GDS V + +A LS+E ++
Sbjct: 235 VNPQGKVVNTVGSGDSTVAGMVAGIA--SGLSIEKAFQQA 272
>4N08-A nrPDB
Length = 348
Score = 41.6 bits (96), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 66/289 (22%), Positives = 116/289 (40%), Gaps = 36/289 (12%)
Query: 52 GGKGAN-----QCVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAAT 106
GG G N Q +Q A G + V + D +G E + I + TK A +
Sbjct: 65 GGSGLNVARVAQWMQQAYKGKFVTYVGCIADDRYGKVLKEAAEHEGIVMAVEHTTK-AGS 123
Query: 107 GTASIIVNNEGQNIIVIVAGANLLLNTEDLRAAANV--ISRAKVMVCQ---LEITPATSL 161
G ++ + + + ++ + AN L ++E +R+ A V + +++ L + L
Sbjct: 124 GACAVCITGKERTLVADLGAANHL-SSEHMRSPAVVRAMDESRIFYFSGFTLTVDVNHVL 182
Query: 162 EALTMARR-SGVKTLFNPAPAIADLDPQFYT--------LSDVFCCNESEAEILTGLT-- 210
+A AR G+ + AP I QF++ +D+ N EA+ +
Sbjct: 183 QACRKAREVDGLFMINLSAPFIM----QFFSAQLGEVLPYTDIIVANRHEAKEFANMMKW 238
Query: 211 ----VGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPT-EKVKAVDTT 265
V A + + +VV+ T E V+ ++ E +P ++ K +D
Sbjct: 239 DTDCVEEIARRAVSEVPYTGTKGRVVVFTRDIESTVLATKDGVETVPVPQLDQDKVIDMN 298
Query: 266 GAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPYK 314
GAGD+F+G F AY L ++ A +Q G S+P K
Sbjct: 299 GAGDAFMG--GFLSAYAVGKDLRRCCETGHYTAQEVIQRDGC--SFPEK 343
>5KB6-A nrPDB
Length = 363
Score = 41.6 bits (96), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 59/264 (22%), Positives = 111/264 (42%), Gaps = 30/264 (11%)
Query: 75 VGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTE 134
+G D FG + + Y+ + TGT + + ++++ +A AN +
Sbjct: 108 IGIDKFGEILKRKAADAHVDAHY-YEQNEQPTGTCAACITGGNRSLVANLAAANCYKKEK 166
Query: 135 DLRAAAN--VISRAKVMVCQ---LEITPATSLE-ALTMARRSGVKTLFNPAPAIADLDPQ 188
L N ++ +A+V L ++P + L+ A A + V TL AP I+ Q
Sbjct: 167 HLDLERNWVLVEKARVYYIAGFFLTVSPESVLKVARYAAENNRVFTLNLSAPFIS----Q 222
Query: 189 FYTLS--------DVFCCNESEAEILT---GLTVGSAADAGEAALVLLK---RGCQVVII 234
F+ + D+ NE+EA G + + A L K + + VI
Sbjct: 223 FFKEALMDVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIF 282
Query: 235 TLGAEGCVVLSQTEPEPKHIPTE-KVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNR 293
T G + +V ++ + + + + + +DT GAGD+FVG F + L + +
Sbjct: 283 TQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVG--GFLSQLVSDKPLTECIRA 340
Query: 294 SNFIAAVSVQAAGTQSSYPYKKDL 317
++ A+V ++ G ++P K D
Sbjct: 341 GHYAASVIIRRTGC--TFPEKPDF 362
>2HW1-A nrPDB
Length = 298
Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 57/287 (19%), Positives = 110/287 (38%), Gaps = 39/287 (13%)
Query: 14 EVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVC 73
E ++ VG + D++SL + PK I GG +N C + LGA + +
Sbjct: 2 EEKQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMG 61
Query: 74 KVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNT 133
+ + +++L++ + +T + A++I+N +G+ +L
Sbjct: 62 SMAPGHVADFVLDDLRRYSVDLRYTVFQTTGSVPIATVIINE--------ASGSRTILYY 113
Query: 134 EDLRAAANVISRAKVMVCQ---LEITPATSLEALTMARRSGVKTLFNPAP-----AIADL 185
+ + KV + Q + I + E + M +R P ++
Sbjct: 114 DRSLPDVSATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVE 173
Query: 186 DP-----QFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVII------ 234
P Q + DV ++ ++ L SA +A +++G +V
Sbjct: 174 KPREELFQLFGYGDVVFVSK---DVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGA 230
Query: 235 -TLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLA 280
LG +G ++ S P P + VDT GAGD+F ++ F L+
Sbjct: 231 DALGPDGKLLHSDAFPPP--------RVVDTLGAGDTFNASVIFSLS 269
>3UQ9-A nrPDB
Length = 372
Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 65/267 (24%), Positives = 117/267 (43%), Gaps = 23/267 (8%)
Query: 70 SMVCKVGKDSFGNDYIEN-LKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGA- 127
S V +G D G YI+N D+ TEF + TG +++V+ + ++++ + A
Sbjct: 104 SYVGCIGADIQGK-YIKNDCSALDLVTEFQIAEEPLMTGKVAVLVSEKLRSMVTYLGAAC 162
Query: 128 NLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRS--GVKTL-FN-PAPAIA 183
+L L + +++ +A+V + L +A+ S K FN AP ++
Sbjct: 163 DLSLAHIEQPHVWSLVEKAQVYYIAGFVINTCYEGMLKIAKHSLENEKLFCFNLSAPFLS 222
Query: 184 DLD----PQFYTLSDVFCCNESEAE-------ILTGLTVGSAADAGEAALVLLKRGCQVV 232
+ + + S++ NESEAE +L +A + K+ ++V
Sbjct: 223 QFNTKEVDEMISYSNIVFGNESEAEAYGEVHGLLEDTVHATARYIADLPFADGKKRKRLV 282
Query: 233 IITLGAEGCVVLSQTEPEPKHIPTEKVK---AVDTTGAGDSF-VGALAFYLAYYPNL-SL 287
IIT G + ++ E E+ K +DT GAGD+F G +A Y+ P + SL
Sbjct: 283 IITRGKNPLLYTDSSDSEIHQFMVEQFKDDQIIDTNGAGDAFAAGFIADYIRGKPMITSL 342
Query: 288 EDMLNRSNFIAAVSVQAAGTQSSYPYK 314
+ + +I S + G++ SY K
Sbjct: 343 HAAVKAAAYIICRSGFSLGSRDSYSLK 369
>3KD6-A nrPDB
Length = 313
Score = 39.3 bits (90), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 31/99 (31%), Positives = 48/99 (48%), Gaps = 10/99 (10%)
Query: 194 DVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTE--PEP 251
DVF N+SEA +L+G + + A ++ + G + +II G G ++ + P
Sbjct: 170 DVFIVNDSEARLLSG-----DPNLVKTARIIREMGPKTLIIKKGEHGALLFTDNGIFAAP 224
Query: 252 KHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDM 290
P E + D TGAGD+F G +LA N S +M
Sbjct: 225 A-FPLESI--YDPTGAGDTFAGGFIGHLARCGNTSEAEM 260
>2VAR-A nrPDB
Length = 313
Score = 38.9 bits (89), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 63/279 (22%), Positives = 108/279 (38%), Gaps = 34/279 (12%)
Query: 25 MTDLVSLTSRLPKTGETIHGHKFFIGF-----GGKGANQCVQAARLGAMTSMVCKVGKDS 79
M D+++L L + G F+ + G N C+ R S++ +VG D
Sbjct: 1 MVDVIALGEPLIQFNSFNPGPLRFVNYFEKHVAGSELNFCIAVVRNHLSCSLIARVGNDE 60
Query: 80 FGNDYIENLKQNDISTEFTYQTKDAATGTASI----IVNNEGQNIIVIVAGANLLLNTED 135
FG + IE + I T ++ TG I + + + + A L+ ED
Sbjct: 61 FGKNIIEYSRAQGIDTSHIKVDNESFTGIYFIQRGYPIPMKSELVYYRKGSAGSRLSPED 120
Query: 136 LRAAANVISRAKVMVCQLEITPATS-------LEALTMARRSGVKTLFNPAPAIADLDPQ 188
+ N + ++ +V IT A S ++A +A+ + T P + +
Sbjct: 121 IN--ENYVRNSR-LVHSTGITLAISDNAKEAVIKAFELAKSRSLDTNIRPKLWSSLEKAK 177
Query: 189 FYTLS-------DVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGC 241
LS +V + + +IL +T D EA + G +V++ LG++G
Sbjct: 178 ETILSILKKYDIEVLITDPDDTKILLDVT-----DPDEAYRKYKELGVKVLLYKLGSKGA 232
Query: 242 VVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGAL-AFYL 279
+ K KV D TGAGD+ G + YL
Sbjct: 233 IAYKDNVKAFKD--AYKVPVEDPTGAGDAMAGTFVSLYL 269
>3NCA-A nrPDB
Length = 313
Score = 38.9 bits (89), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 58/286 (20%), Positives = 111/286 (38%), Gaps = 41/286 (14%)
Query: 16 AAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKV 75
+ ++ VG + D++SL + PK I GG +N C + LGA + + +
Sbjct: 19 SQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSM 78
Query: 76 GKDSFGNDYIENLKQNDIS-TEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTE 134
+ + + ++ + ++ +Q+K + II N+ G IV+ + ++
Sbjct: 79 APGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSAT 138
Query: 135 DLRAAANVISRAKVMVCQ---LEITPATSLEALTMARRSGVKTLFNPAP-----AIADLD 186
D KV + Q + I + E + M +R P ++
Sbjct: 139 DFE---------KVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEK 189
Query: 187 P-----QFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVII------- 234
P Q + DV ++ ++ L SA +A +++G +V
Sbjct: 190 PREELFQLFGYGDVVFVSK---DVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGAD 246
Query: 235 TLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLA 280
LG +G ++ S P P + VDT GAGD+F ++ F L+
Sbjct: 247 ALGPDGKLLHSDAFPPP--------RVVDTLGAGDTFNASVIFSLS 284
>3B1N-A nrPDB
Length = 326
Score = 37.4 bits (85), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 56/276 (20%), Positives = 107/276 (38%), Gaps = 31/276 (11%)
Query: 51 FGGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTAS 110
FGG N LG M+ +G Y++ + +S E+ D + A
Sbjct: 46 FGGCAGNIAYALNLLGGDARMMGTLGAVD-AQPYLDRMDALGLSREYVRVLPDTYSAQAM 104
Query: 111 IIVNNEGQNIIVIVAGANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMAR-- 168
I + + I GA + ++ N AK + +L I + +
Sbjct: 105 ITTDLDNNQITAFHPGAMM-------QSHVNHAGEAKDI--KLAIVGPDGFQGMVQHTEE 155
Query: 169 --RSGVKTLFNPAPAIADLD----PQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAAL 222
++GV +F+P + D + L+ N+ EA+++ T G + D
Sbjct: 156 LAQAGVPFIFDPGQGLPLFDGATLRRSIELATYIAVNDYEAKLVCDKT-GWSEDE----- 209
Query: 223 VLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPTEKV-KAVDTTGAGDSFVGALAFYLAY 281
+ Q +IIT G G + + E IP + + +D TG GD+F G L + + +
Sbjct: 210 --IASRVQALIITRGEHGATIRHRDGTE--QIPAVRAERVIDPTGCGDAFRGGLLYGIEH 265
Query: 282 YPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPYKKDL 317
+ + L ++ + A+ + G Q+ P + ++
Sbjct: 266 GFDWATAGRL--ASLMGALKIAHQGPQTYAPTRAEI 299
>1YGJ-A nrPDB
Length = 312
Score = 37.0 bits (84), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 36/133 (27%), Positives = 54/133 (40%), Gaps = 17/133 (12%)
Query: 168 RRSGVKTLFNPAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKR 227
+R+G ++ P + + ++D+ N+ EAE+LTG + S +A E +L
Sbjct: 119 QRNGEGAMYVPDDLLPVYREKVVPVADIITPNQFEAELLTGRKIHSQEEALEVMDMLHSM 178
Query: 228 GCQVVIIT----LGAEGCVVL----SQTEPEPK--------HIPTEKVKAVDTTGAGDSF 271
G V+IT L G L SQ P + KV AV G GD F
Sbjct: 179 GPDTVVITSSNLLSPRGSDYLMALGSQRTRAPDGSVVTQRIRMEMHKVDAV-FVGTGDLF 237
Query: 272 VGALAFYLAYYPN 284
L + +PN
Sbjct: 238 AAMLLAWTHKHPN 250
>2F7K-A nrPDB
Length = 327
Score = 35.8 bits (81), Expect = 0.029, Method: Compositional matrix adjust.
Identities = 38/161 (23%), Positives = 67/161 (41%), Gaps = 20/161 (12%)
Query: 168 RRSGVKTLFNPAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKR 227
+ G +++ P + + L+D+ N+ EAE+L+G + S +A +L
Sbjct: 134 KWDGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSM 193
Query: 228 GCQVVIIT-------LGAEGCVVL-SQTEPEPK--------HIPTEKVKAVDTTGAGDSF 271
G V+IT G+ +VL SQ P + KV AV G GD F
Sbjct: 194 GPDTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAV-FVGTGDLF 252
Query: 272 VGALAFYLAYYPN---LSLEDMLNRSNFIAAVSVQAAGTQS 309
L + +PN ++ E ++ + + ++Q A Q+
Sbjct: 253 AAMLLAWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQA 293
>3BF5-A nrPDB
Length = 306
Score = 33.5 bits (75), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 36/136 (26%), Positives = 57/136 (41%), Gaps = 24/136 (17%)
Query: 158 ATSLEALTMARRSGVKTLFNPAPAI----ADLDPQFYTLSDVFCCNESEAEILTGLTVGS 213
+T L MA+ K +F+P+ I D +F+ +S + N+ E + +T S
Sbjct: 147 STGPNYLDMAKSIRSKIIFDPSQEIHKYSKDELKKFHEISYMSIFNDHEYRVFREMTGLS 206
Query: 214 AADAGEAALVLLKRGCQVVIITLGAEGC-VVLSQTEPEPKHIPTEKVKAVDTTGAGDSFV 272
+ I+T G G + + + + IP+ + DT GAGDSF
Sbjct: 207 SPKV-------------TTIVTNGERGSSLFMDGKKYDFPAIPS----SGDTVGAGDSFR 249
Query: 273 GALAFYLAYYPNLSLE 288
L YLA Y S+E
Sbjct: 250 AGL--YLALYNRRSIE 263
>2AFB-A nrPDB
Length = 351
Score = 32.7 bits (73), Expect = 0.23, Method: Compositional matrix adjust.
Identities = 71/318 (22%), Positives = 111/318 (34%), Gaps = 47/318 (14%)
Query: 18 VVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGK 77
VV G M L P F + +GG AN A++G V K+
Sbjct: 15 VVTFGEIMLRLSP-----PDHKRIFQTDSFDVTYGGAEANVAAFLAQMGLDAYFVTKLPN 69
Query: 78 DSFGNDYIENLKQNDISTEFT---------YQTKDAATGTASIIVNNEGQNIIVIVAGAN 128
+ G+ +L++ + T++ Y + A+ S +V + + I +
Sbjct: 70 NPLGDAAAGHLRKFGVKTDYIARGGNRIGIYFLEIGASQRPSKVVYDRAHSAISEAKRED 129
Query: 129 LLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKT---------LFNPA 179
+ E + A + + + P +AL +A GV L+
Sbjct: 130 F--DWEKILDGARWFHFSGITPPLGKELPLILEDALKVANEKGVTVSCDLNYRARLWTKE 187
Query: 180 PAIADLDPQFYTLSDVFCCNESEAEILTGLTV----------GSAADAGEAALVLLKRGC 229
A + P F DV NE + E + G++V A A A V K
Sbjct: 188 EAQKVMIP-FMEYVDVLIANEEDIEKVLGISVEGLDLKTGKLNREAYAKIAEEVTRKYNF 246
Query: 230 QVVIITLG------AEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYP 283
+ V ITL V+ +P ++ VD GAGDSF GAL Y
Sbjct: 247 KTVGITLRESISATVNYWSVMVFENGQPHFSNRYEIHIVDRVGAGDSFAGALI-----YG 301
Query: 284 NLSLEDMLNRSNFIAAVS 301
+L D ++ F AA S
Sbjct: 302 SLMGFDSQKKAEFAAAAS 319
>2AWD-A nrPDB
Length = 323
Score = 31.6 bits (70), Expect = 0.45, Method: Compositional matrix adjust.
Identities = 16/53 (30%), Positives = 30/53 (56%), Gaps = 2/53 (3%)
Query: 228 GCQVVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLA 280
G + ++I+LG +G + + IPT ++A + G+GD+ + LA+ LA
Sbjct: 218 GIEWIVISLGKDGAIAKHHDQFYRVKIPT--IQAKNPVGSGDATIAGLAYGLA 268
>1HKH-A nrPDB
Length = 279
Score = 29.6 bits (65), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 20/79 (25%), Positives = 34/79 (43%), Gaps = 5/79 (6%)
Query: 205 ILTGLTVGSAADAGEAALVLLKRGCQ-VVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVD 263
+L G ++G+ GE A + + G + V + A L Q + P+ +P E ++
Sbjct: 93 VLVGFSMGT----GELARYVARYGHERVAKLAFLASLEPFLVQRDDNPEGVPQEVFDGIE 148
Query: 264 TTGAGDSFVGALAFYLAYY 282
GD F FY +Y
Sbjct: 149 AAAKGDRFAWFTDFYKNFY 167
>4GM6-A nrPDB
Length = 351
Score = 29.3 bits (64), Expect = 2.3, Method: Compositional matrix adjust.
Identities = 16/55 (29%), Positives = 26/55 (47%)
Query: 49 IGFGGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKD 103
I GG AN V ++LG T + V + G +E+L ++ + T F + D
Sbjct: 53 IHIGGAEANVAVNLSKLGHPTRIATVVPANPIGKMAVEHLWRHQVDTAFVVEAGD 107
>2AA0-A nrPDB
Length = 383
Score = 28.9 bits (63), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 12/21 (57%), Positives = 15/21 (71%)
Query: 260 KAVDTTGAGDSFVGALAFYLA 280
K VDT GAGD+FVG + L+
Sbjct: 329 KIVDTNGAGDAFVGGFLYALS 349
>3LUF-A nrPDB
Length = 259
Score = 28.1 bits (61), Expect = 4.9, Method: Compositional matrix adjust.
Identities = 21/48 (43%), Positives = 26/48 (54%), Gaps = 2/48 (4%)
Query: 189 FYTLSDVFCCNESEAEI-LTGLTVGSAADAGEAALVLLKRGCQVVIIT 235
F TL C E + L LT+ A +GEA VLL+RG VVI+T
Sbjct: 35 FDTLEGARHCQGDEYVVALVDLTLPDAP-SGEAVKVLLERGLPVVILT 81
>3JUL-A nrPDB
Length = 320
Score = 27.7 bits (60), Expect = 6.6, Method: Compositional matrix adjust.
Identities = 19/49 (38%), Positives = 29/49 (59%), Gaps = 2/49 (4%)
Query: 232 VIITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLA 280
++++LGA+G + + + IP KV+ + TGAGD FVGA LA
Sbjct: 218 LVVSLGAKGSIC-AHNGKLYQVIPP-KVQERNDTGAGDVFVGAFIAGLA 264
>1OXJ-A nrPDB
Length = 173
Score = 27.7 bits (60), Expect = 7.2, Method: Compositional matrix adjust.
Identities = 17/71 (23%), Positives = 37/71 (52%)
Query: 125 AGANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIAD 184
A L L + L+ AN+++R + + ++ +T++E LT + +K L +P P +
Sbjct: 51 ASHKLALCIDKLKERANILNRVEQELLSGQMELSTAVEELTNIVLTPMKPLESPGPPEEN 110
Query: 185 LDPQFYTLSDV 195
+ +F + D+
Sbjct: 111 IGLRFLKVIDI 121
Searching..................................................done
Results from round 2
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
5C40-A nrPDB 407 e-114
5ZWY-A nrPDB 302 2e-82
4X8F-A nrPDB 293 6e-80
3RY7-A nrPDB 280 4e-76
1VM7-A nrPDB 277 4e-75
1RK2-A nrPDB 276 1e-74
6ILS-A nrPDB 266 8e-72
1TYY-A nrPDB 226 1e-59
3HJ6-A nrPDB 222 1e-58
2C4E-A nrPDB 220 7e-58
6CW5-A nrPDB 220 9e-58
5EYN-A nrPDB 213 1e-55
3KZH-A nrPDB 207 5e-54
2QCV-A nrPDB 203 1e-52
1WYE-A nrPDB 202 2e-52
3H49-A nrPDB 201 4e-52
5KB6-A nrPDB 198 2e-51
2I6B-A nrPDB 198 3e-51
3GBU-A nrPDB 195 2e-50
3I3Y-A nrPDB 194 6e-50
4DU5-A nrPDB 190 8e-49
1V1S-A nrPDB 187 7e-48
3IQ0-A nrPDB 186 1e-47
3UBO-A nrPDB 185 2e-47
3PL2-A nrPDB 183 1e-46
4N08-A nrPDB 181 4e-46
2RBC-A nrPDB 180 6e-46
4LC4-A nrPDB 179 1e-45
3LHX-A nrPDB 178 2e-45
4WJM-A nrPDB 178 3e-45
3LJS-A nrPDB 172 2e-43
2HW1-A nrPDB 170 7e-43
3LOO-A nrPDB 167 6e-42
3GO6-A nrPDB 163 8e-41
2QHP-A nrPDB 161 3e-40
2NWH-A nrPDB 158 5e-39
3N1C-A nrPDB 148 3e-36
2JG5-A nrPDB 103 1e-22
Sequences not found previously or not previously below threshold:
2VAR-A nrPDB 166 1e-41
3NCA-A nrPDB 159 2e-39
2AA0-A nrPDB 127 5e-30
3UQ9-A nrPDB 116 2e-26
2ABQ-A nrPDB 115 3e-26
3KD6-A nrPDB 114 6e-26
3B1N-A nrPDB 113 1e-25
4E84-A nrPDB 111 6e-25
6C9R-A nrPDB 109 2e-24
4E69-A nrPDB 106 1e-23
2AFB-A nrPDB 106 2e-23
3JUL-A nrPDB 101 6e-22
2AWD-A nrPDB 100 7e-22
4GM6-A nrPDB 97 8e-21
3BF5-A nrPDB 96 2e-20
2Q5R-A nrPDB 88 6e-18
2AJR-A nrPDB 84 7e-17
3KTN-A nrPDB 68 4e-12
5YSQ-A nrPDB 61 7e-10
4S1M-A nrPDB 59 4e-09
1YGJ-A nrPDB 56 3e-08
2F7K-A nrPDB 54 1e-07
2I5B-A nrPDB 54 1e-07
4JJP-A nrPDB 53 2e-07
1TD2-A nrPDB 46 2e-05
2DDM-A nrPDB 46 2e-05
3PZS-A nrPDB 45 4e-05
5TQI-A nrPDB 44 8e-05
5B6A-A nrPDB 44 1e-04
1UB0-A nrPDB 43 2e-04
3ZS7-A nrPDB 42 4e-04
3MBJ-A nrPDB 38 0.006
4XF7-A nrPDB 37 0.008
3HYO-A nrPDB 36 0.017
4YL5-A nrPDB 36 0.027
5MEK-A nrPDB 36 0.034
5ZWB-B nrPDB 35 0.044
4I8O-A nrPDB 32 0.29
3CGD-A nrPDB 32 0.38
6CY1-A nrPDB 30 1.2
1J08-A nrPDB 30 1.6
1BJ4-A nrPDB 29 3.8
1OXJ-A nrPDB 28 5.5
4EVZ-A nrPDB 27 9.5
>5C40-A nrPDB
Length = 330
Score = 407 bits (1045), Expect = e-114, Method: Composition-based stats.
Identities = 322/322 (100%), Positives = 322/322 (100%)
Query: 1 MAASGEPQRQWQEEVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCV 60
MAASGEPQRQWQEEVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCV
Sbjct: 1 MAASGEPQRQWQEEVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCV 60
Query: 61 QAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNI 120
QAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNI
Sbjct: 61 QAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNI 120
Query: 121 IVIVAGANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAP 180
IVIVAGANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAP
Sbjct: 121 IVIVAGANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAP 180
Query: 181 AIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEG 240
AIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEG
Sbjct: 181 AIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEG 240
Query: 241 CVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAV 300
CVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAV
Sbjct: 241 CVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAV 300
Query: 301 SVQAAGTQSSYPYKKDLPLTLF 322
SVQAAGTQSSYPYKKDLPLTLF
Sbjct: 301 SVQAAGTQSSYPYKKDLPLTLF 322
>5ZWY-A nrPDB
Length = 349
Score = 302 bits (772), Expect = 2e-82, Method: Composition-based stats.
Identities = 130/316 (41%), Positives = 179/316 (56%), Gaps = 13/316 (4%)
Query: 13 EEVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMV 72
E ++VVGSC D V +P+ GET+H F GFGGKGANQ V A RLGA +MV
Sbjct: 33 EYAPDILVVGSCFLDYVGYVDHMPQVGETMHSVSFHKGFGGKGANQAVAAGRLGAKVAMV 92
Query: 73 CKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNE-GQNIIVIVAGANLLL 131
VG D G+DYI+ L++N + T + ++T ++TG A I+V+ + N IVI A
Sbjct: 93 SMVGTDGDGSDYIKELERNGVDTAYMFRTGKSSTGLAMILVDTKSSNNEIVICPNATNHF 152
Query: 132 NTEDLRAAANVISRA-----KVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLD 186
E LRA N R K ++CQ EI T+L+ + A GV T+FN APA +
Sbjct: 153 TPELLRAQTNNYERILHTGLKYLICQNEIPLPTTLDTIKEAHSRGVYTVFNSAPAPKPAE 212
Query: 187 PQ----FYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCV 242
+ F +FC NE EA ++TG+ V A A L + G + V+ITLGA G
Sbjct: 213 VEQIKPFLPYVSLFCPNEVEATLITGVKVTDTESAFSAIKALQQLGVRDVVITLGAAG-F 271
Query: 243 VLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSV 302
VLS+ EP H+ + VKAVDTTGAGD FVG++ ++++ +L + R+N AA+SV
Sbjct: 272 VLSENGAEPVHVTGKHVKAVDTTGAGDCFVGSMVYFMSR--GRNLLEACKRANECAAISV 329
Query: 303 QAAGTQSSYPYKKDLP 318
GTQ SYP+ +LP
Sbjct: 330 TRKGTQLSYPHPSELP 345
>4X8F-A nrPDB
Length = 309
Score = 293 bits (750), Expect = 6e-80, Method: Composition-based stats.
Identities = 110/308 (35%), Positives = 160/308 (51%), Gaps = 5/308 (1%)
Query: 14 EVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVC 73
+ +VV+GS D V P+ GET+HG + + GGKGANQ V AAR+ A +
Sbjct: 3 HMNKLVVLGSVNADHVLQVPSFPRPGETLHGRNYQVIPGGKGANQAVAAARMQADVGFIA 62
Query: 74 KVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNT 133
VG DSFG + E+ K + I+T + TG A I V++ G+N I I A AN L
Sbjct: 63 CVGDDSFGINIRESFKLDGINTAGVKLQPNCPTGIAMIQVSDSGENSICISAEANAKLTA 122
Query: 134 EDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDPQFYTLS 193
+ I A+ ++ QLE L+A A+ + + NPAPA +L +
Sbjct: 123 AAIEPDLAAIRDARYLLMQLETPLDGILKAAQEAKTAKTNVILNPAPA-RELPDELLKCV 181
Query: 194 DVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKH 253
D+ NE+EAE+LTG+TV + A +AA L +G ++VIITLG++G + +
Sbjct: 182 DLITPNETEAEVLTGITVYDDSSAQQAADALHCKGIEIVIITLGSKGVWLSQN--GRGQR 239
Query: 254 IPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPY 313
IP VKA DTT AGD+F GAL + LE + ++ AA+SV G Q+S P
Sbjct: 240 IPGFVVKATDTTAAGDTFNGALV--TGLLQEMPLESAIKFAHAAAAISVTRFGAQTSIPT 297
Query: 314 KKDLPLTL 321
+ ++ L
Sbjct: 298 RAEVEAFL 305
>3RY7-A nrPDB
Length = 304
Score = 280 bits (717), Expect = 4e-76, Method: Composition-based stats.
Identities = 109/302 (36%), Positives = 167/302 (55%), Gaps = 5/302 (1%)
Query: 17 AVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGG-KGANQCVQAARLGAMTSMVCKV 75
VV++GS D R + GET+H + FGG KGANQ + AR+ A T+ + K+
Sbjct: 4 KVVILGSTNVDQFLTVERYAQPGETLHVEEAQKAFGGGKGANQAIATARMQADTTFITKI 63
Query: 76 GKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTED 135
G D + +E+ K I T + +T +A TG A I VN EGQN I + GAN+ + ED
Sbjct: 64 GTDGVADFILEDFKVAHIDTSYIIKTAEAKTGQAFITVNAEGQNTIYVYGGANMTMTPED 123
Query: 136 LRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDPQFYTLSDV 195
+ A + I A +V QLE+ + A +A+ GV T+ NPAPA A L + +L D+
Sbjct: 124 VINAKDAIINADFVVAQLEVPIPAIISAFEIAKAHGVTTVLNPAPAKA-LPNELLSLIDI 182
Query: 196 FCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIP 255
NE+EAE+L+G+ V + + A L G + V+ITLG +G ++ + +HI
Sbjct: 183 IVPNETEAELLSGIKVTNEQSMKDNANYFLSIGIKTVLITLGKQGTYFATKN--QSQHIE 240
Query: 256 TEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPYKK 315
KV A+DTT AGD+F+GA L + +L D ++ N ++++VQ G Q+S P +
Sbjct: 241 AYKVNAIDTTAAGDTFIGAFVSRLNKSQD-NLADAIDFGNKASSLTVQKHGAQASIPLLE 299
Query: 316 DL 317
++
Sbjct: 300 EV 301
>1VM7-A nrPDB
Length = 311
Score = 277 bits (709), Expect = 4e-75, Method: Composition-based stats.
Identities = 106/305 (34%), Positives = 154/305 (50%), Gaps = 14/305 (4%)
Query: 18 VVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAM-TSMVCKVG 76
+ VVGS D+V K GET + + GGKGANQ V A++G V +G
Sbjct: 17 ISVVGSSNIDIVLKVDHFTKPGETQKAIEMNVFPGGKGANQAVTVAKIGEKGCRFVTCIG 76
Query: 77 KDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDL 136
D + + IEN ++ I+ Y TG A I V+ GQN I+I GAN L E +
Sbjct: 77 NDDYSDLLIENYEKLGITG---YIRVSLPTGRAFIEVDKTGQNRIIIFPGANAELKKELI 133
Query: 137 RAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDPQFYTLSDVF 196
N +S + +++ Q EI T+LE A+R +F+PAPA ++ + + D
Sbjct: 134 D--WNTLSESDILLLQNEIPFETTLEC---AKRFNGIVIFDPAPA-QGINEEIFQYLDYL 187
Query: 197 CCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPT 256
NE E E L+ G +AA L+ G + VI+ LG +G +++++ E KH PT
Sbjct: 188 TPNEKEIEALSKDFFGEFLTVEKAAEKFLELGVKNVIVKLGDKGVLLVNKNEK--KHFPT 245
Query: 257 EKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPYKKD 316
KVKAVDTT AGD F GA A L+ + E+ + AA+SV G QSS P +++
Sbjct: 246 FKVKAVDTTAAGDVFNGAFAVALS--EGKNPEEAVIFGTAAAAISVTRLGAQSSIPAREE 303
Query: 317 LPLTL 321
+ L
Sbjct: 304 VEAFL 308
>1RK2-A nrPDB
Length = 309
Score = 276 bits (705), Expect = 1e-74, Method: Composition-based stats.
Identities = 108/309 (34%), Positives = 164/309 (53%), Gaps = 5/309 (1%)
Query: 13 EEVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMV 72
+ ++VV+GS D + P GET+ G+ + + FGGKGANQ V A R GA + +
Sbjct: 2 QNAGSLVVLGSINADHILNLQSFPTPGETVTGNHYQVAFGGKGANQAVAAGRSGANIAFI 61
Query: 73 CKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLN 132
G DS G + L ++I K +TG A I VN EG+N+I I AGAN L+
Sbjct: 62 ACTGDDSIGESVRQQLATDNIDITPVSVIKGESTGVALIFVNGEGENVIGIHAGANAALS 121
Query: 133 TEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDPQFYTL 192
+ A I+ A ++ QLE + + A +A ++ NPAPA +L + L
Sbjct: 122 PALVEAQRERIANASALLMQLESPLESVMAAAKIAHQNKTIVALNPAPA-RELPDELLAL 180
Query: 193 SDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPK 252
D+ NE+EAE LTG+ V + DA +AA VL ++G + V+ITLG+ G + E +
Sbjct: 181 VDIITPNETEAEKLTGIRVENDEDAAKAAQVLHEKGIRTVLITLGSRGVW--ASVNGEGQ 238
Query: 253 HIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYP 312
+P +V+AVDT AGD+F GAL A L + + ++ AA++V G Q S P
Sbjct: 239 RVPGFRVQAVDTIAAGDTFNGAL--ITALLEEKPLPEAIRFAHAAAAIAVTRKGAQPSVP 296
Query: 313 YKKDLPLTL 321
+++++ L
Sbjct: 297 WREEIDAFL 305
>6ILS-A nrPDB
Length = 313
Score = 266 bits (680), Expect = 8e-72, Method: Composition-based stats.
Identities = 89/310 (28%), Positives = 143/310 (46%), Gaps = 5/310 (1%)
Query: 15 VAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCK 74
+VVVGS D+ RLPK GETI GGKGANQ A+L T V +
Sbjct: 2 APPLVVVGSANADIYVEIERLPKEGETISAKTGQTLAGGKGANQAACGAKLMYPTYFVGR 61
Query: 75 VGKDSFGNDYIENLKQNDISTEFTYQT--KDAATGTASIIVNNEGQNIIVIVAGANLLLN 132
+G+D+ G E L + Y + TG A +++ ++GQN I+IV GAN+
Sbjct: 62 LGEDAHGKLIAEALGDDGCGVHLDYVRSVNNEPTGHAVVMLQSDGQNSIIIVGGANMKAW 121
Query: 133 TEDL-RAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDPQFYT 191
E + ++ A +++ Q EI + +++ +++GV + + + +
Sbjct: 122 PEIMSDDDLEIVRNAGIVLLQREIPDSINIQVAKAVKKAGVPVILDVGGMDTPIPNELLD 181
Query: 192 LSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEP 251
D+ NE+E LTG+ + +A K G + V++ LG++G + Q E
Sbjct: 182 SIDILSPNETELSRLTGMPTETFEQISQAVAKCHKLGVKQVLVKLGSKGSALFIQGEKPI 241
Query: 252 KHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSY 311
+ + VDTTGAGD+F A F +A S E+ L + A++ VQ G S
Sbjct: 242 QQSIIPAAQVVDTTGAGDTFTAA--FAVAMVEGKSHEECLRFAAAAASLCVQVKGAIPSM 299
Query: 312 PYKKDLPLTL 321
P +K + L
Sbjct: 300 PDRKSVLKLL 309
>1TYY-A nrPDB
Length = 339
Score = 226 bits (575), Expect = 1e-59, Method: Composition-based stats.
Identities = 79/331 (23%), Positives = 129/331 (38%), Gaps = 35/331 (10%)
Query: 7 PQRQWQEEVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLG 66
P+ + + V V+G DLV + GG AN V ARLG
Sbjct: 16 PRGSHMKAMNKVWVIGDASVDLVPEKQN-----------SYLKCPGGASANVGVCVARLG 64
Query: 67 AMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNII--VIV 124
+ +G D G + + N + F D + + + +G+ ++
Sbjct: 65 GECGFIGCLGDDDAGRFLRQVFQDNGVDVTFLRLDADLTSAVLIVNLTADGERSFTYLVH 124
Query: 125 AGANLLLNTEDLRAAANVISRAKVMVCQLEITPATS--LEALTMARRSGVKTLFNP---- 178
GA+ ++ +DL L PA LE R +G LF+
Sbjct: 125 PGADTYVSPQDL-PPFRQYEWFYFSSIGLTDRPAREACLEGARRMREAGGYVLFDVNLRS 183
Query: 179 -APAIADLDPQFY----TLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVI 233
D P+ L+ + + E L+G A+ +A L GC I
Sbjct: 184 KMWGNTDEIPELIARSAALASICKVSADELCQLSG-----ASHWQDARYYLRDLGCDTTI 238
Query: 234 ITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAY---YPNLSLEDM 290
I+LGA+G ++++ H P +V VDTTGAGD+FVG L F L+ + + L +
Sbjct: 239 ISLGADGALLITAEGE--FHFPAPRVDVVDTTGAGDAFVGGLLFTLSRANCWDHALLAEA 296
Query: 291 LNRSNFIAAVSVQAAGTQSSYPYKKDLPLTL 321
++ +N A++V A G ++ P+ L L
Sbjct: 297 ISNANACGAMAVTAKGAMTALPFPDQLNTFL 327
>3HJ6-A nrPDB
Length = 327
Score = 222 bits (566), Expect = 1e-58, Method: Composition-based stats.
Identities = 77/315 (24%), Positives = 129/315 (40%), Gaps = 30/315 (9%)
Query: 17 AVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVG 76
VV +G + D++S ++ FGG AN V +RLG +++ ++G
Sbjct: 23 DVVSLGEILVDMISTEE----VNSLSQSREYTRHFGGSPANIAVNLSRLGKKVALISRLG 78
Query: 77 KDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDL 136
D+FGN ++ LK I T+ Q K+ T + + + + A++ L +D+
Sbjct: 79 ADAFGNYLLDVLKGEQIITDGIQQDKERRTTIVYVSKSTRTPDWLPYRE-ADMYLQEDDI 137
Query: 137 RAAANVISRAKVMVCQLEI-----TPATSLEALTMARRSGVKTLFNP---------APAI 182
+I R+KV I T+++A AR G F+P
Sbjct: 138 --IFELIKRSKVFHLSTFILSRKPARDTAIKAFNYAREQGKIVCFDPCYRKVLWPEGDDG 195
Query: 183 ADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCV 242
A + + + +D + +A L G L+ G + VI+TLG EG
Sbjct: 196 AGVVEEIISRADFVKPSLDDARHLFG-----PDSPENYVKRYLELGVKAVILTLGEEG-- 248
Query: 243 VLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSV 302
V++ E IP AVD TGAGD+F F +++ + N +AA +
Sbjct: 249 VIASDGEEIIRIPAFSEDAVDVTGAGDAFWS--GFICGLLDGYTVKRSIKLGNGVAAFKI 306
Query: 303 QAAGTQSSYPYKKDL 317
+ G S P K+D+
Sbjct: 307 RGVGALSPVPSKEDI 321
>2C4E-A nrPDB
Length = 302
Score = 220 bits (560), Expect = 7e-58, Method: Composition-based stats.
Identities = 68/308 (22%), Positives = 115/308 (37%), Gaps = 30/308 (9%)
Query: 14 EVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVC 73
++ + VG D + + P+ +I +GG AN V +LG + ++
Sbjct: 4 KMEKITCVGHTALDYIFNVEKFPEPNTSIQIPSARKYYGGAAANTAVGIKKLGVNSELLS 63
Query: 74 KVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLL--- 130
VG D + Y LK DI+ Y +++ T A I + + I + GA
Sbjct: 64 CVGYDFKNSGYERYLKNLDINISKLYYSEEEETPKAWIFTDKDNNQITFFLWGAAKHYKE 123
Query: 131 LNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDPQFY 190
LN + I+ P +L+ A + + F+P + +
Sbjct: 124 LNPPNFNTEIVHIATGD---------PEFNLKCAKKAYGNNL-VSFDPGQDLPQYSKEML 173
Query: 191 ----TLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQ 246
++ N+ E E + L D E +I+T G++G V+ ++
Sbjct: 174 LEIIEHTNFLFMNKHEFERASNLLNFEIDDYLE--------RVDALIVTKGSKGSVIYTK 225
Query: 247 TEPEPKHIPTEKV-KAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAA 305
+ IP K K +D TGAGDS+ F AY LE A+ V+A
Sbjct: 226 DKK--IEIPCIKAGKVIDPTGAGDSYRA--GFLSAYVKGYDLEKCGLIGAATASFVVEAK 281
Query: 306 GTQSSYPY 313
G Q++ P
Sbjct: 282 GCQTNLPT 289
>6CW5-A nrPDB
Length = 332
Score = 220 bits (559), Expect = 9e-58, Method: Composition-based stats.
Identities = 91/317 (28%), Positives = 133/317 (41%), Gaps = 31/317 (9%)
Query: 19 VVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGKD 78
+V GS D + + GETI GGKGANQ AR G + +G D
Sbjct: 16 LVRGSVNIDEFFHLPHIVRPGETISSTGLTKRAGGKGANQAFAVARAGGQVELDGAIGDD 75
Query: 79 SFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDLRA 138
G E L+ + T+ KD TG A I +G+N IV+ AGAN L +
Sbjct: 76 --GIWVKEMLESAGVGTDKLKIVKDEVTGRAVIQSAADGENSIVLHAGANYYLPSPTPTT 133
Query: 139 AANVISRAKVMVCQLEITPATSLEALTMARRSG--VKTLFNPAPAI--ADLDPQFYTLSD 194
+ + ++ Q E+ +++L LT A +S + ++FNP+P + A L +
Sbjct: 134 SLATYTH---LLVQNEVPLSSTLAYLTAAGQSSPPLTSVFNPSPMLTPAQLREFPWKHLS 190
Query: 195 VFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQV----------------VIITLGA 238
NE E L L GS+A+ GEA L+ +I TLGA
Sbjct: 191 WLIVNEGELGDLL-LAFGSSANPGEAKEDELQAKASAGILELHENDYFSKNVGIICTLGA 249
Query: 239 EGCVVLSQTEPEPKHIPTEKVK--AVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNF 296
+G ++ + E ++P K++ DTTGAGD F G F SL+D L
Sbjct: 250 KG-ILCYEPGKEVGYLPAAKLQNPVKDTTGAGDCFAGY--FVAGLMSGKSLQDALKTCLV 306
Query: 297 IAAVSVQAAGTQSSYPY 313
+ V+ G S P
Sbjct: 307 ACGICVENEGAMESVPT 323
>5EYN-A nrPDB
Length = 323
Score = 213 bits (541), Expect = 1e-55, Method: Composition-based stats.
Identities = 67/324 (20%), Positives = 129/324 (39%), Gaps = 40/324 (12%)
Query: 13 EEVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMV 72
+ ++ V + G + DL+ H + GG AN V ARL ++
Sbjct: 16 DSMSRVWLTGDAVVDLI--------PDGQQH---YLKCPGGAPANVAVAIARLSGRSAFF 64
Query: 73 CKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQN--IIVIVAGANLL 130
+VG D FG + L + + + T T + ++ G+ ++ A+
Sbjct: 65 GRVGNDPFGRFMQQTLTDEQVDCQHLHFDPVHRTSTVVVDLDEHGERSFTFMVKPSADQF 124
Query: 131 LNTEDLRAAANVISRAKVMVCQLEI----TPATSLEALTMARRSGVKTLFNP--APAIAD 184
L D+ + + VC + + + +++ A+ + G F+P +
Sbjct: 125 LQLSDI---PSFQKGEWLHVCSIALANQPSRSSTFAAIAQMKEVGGYVSFDPNLREEVWS 181
Query: 185 LDPQF-------YTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLG 237
+ L+DV +E E + LTG E + +V++TLG
Sbjct: 182 EPQELQATVMRAVGLADVVKFSEEELQFLTGT-----QSIEEGLQAIADFQIPLVVVTLG 236
Query: 238 AEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPN----LSLEDMLNR 293
A+G +V + + + + VK +DTTGAGD+FVG L + L+ + ++ D +
Sbjct: 237 AKGALVATPNSQQI--VSGKAVKPIDTTGAGDAFVGGLLYRLSVAQDWHNQATILDAVKW 294
Query: 294 SNFIAAVSVQAAGTQSSYPYKKDL 317
+N A++ G ++ P + L
Sbjct: 295 ANGCGALATTQKGAMTALPNQAAL 318
>3KZH-A nrPDB
Length = 328
Score = 207 bits (527), Expect = 5e-54, Method: Composition-based stats.
Identities = 67/301 (22%), Positives = 126/301 (41%), Gaps = 17/301 (5%)
Query: 13 EEVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMV 72
+ ++V G+ + D+ + + + GH I FGG N AR+G T+ +
Sbjct: 4 RKEPYLLVFGASVVDVFGFSKASYRPYNSTPGH-VKISFGGVCRNIAENMARVGVNTNFM 62
Query: 73 CKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANL-LL 131
+G D G +E+ K+ + + + +T T I++ G+ + I ++ +
Sbjct: 63 SILGNDEHGKSIVEHSKKIGYHMDDSMVIEGGSTPTYLAILDENGEMVSAIADMKSIGAM 122
Query: 132 NTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPA-----IADLD 186
NT+ + + + A+ V L+ +E L + + +P A + L
Sbjct: 123 NTDFIDSKREIFENAEYTV--LDSDNPEIMEYLLKNFKDKTNFILDPVSAEKASWVKHLI 180
Query: 187 PQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQ 246
F+T N EAEIL G + D +A+ L G + V I+L A+G +
Sbjct: 181 KDFHT----IKPNRHEAEILAGFPITDTDDLIKASNYFLGLGIKKVFISLDADG--IFYN 234
Query: 247 TEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAG 306
I +V + TGAGDSFV L + Y + +ED++ + ++ +++
Sbjct: 235 DGVSCGKIKATEVDVKNVTGAGDSFVAGLGY--GYMNKMPIEDIVKFAMTMSNITISHEE 292
Query: 307 T 307
T
Sbjct: 293 T 293
>2QCV-A nrPDB
Length = 332
Score = 203 bits (515), Expect = 1e-52, Method: Composition-based stats.
Identities = 69/322 (21%), Positives = 127/322 (39%), Gaps = 28/322 (8%)
Query: 17 AVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVG 76
++ +G DL ++ P ET+ F GG AN + +++LG + K+
Sbjct: 13 DLIAIGRACIDLNAVEYNRPME-ETM---TFSKYVGGSPANIVIGSSKLGLKAGFIGKIA 68
Query: 77 KDSFGNDYIENLKQNDISTEFTYQTKDAA-TGTAS--IIVNNEGQNIIVIVAGANLLLNT 133
D G ++ + T ++ TG A I E ++ A+L L+
Sbjct: 69 DDQHGRFIESYMRGVGVDTSNLVVDQEGHKTGLAFTEIKSPEECSILMYRQDVADLYLSP 128
Query: 134 EDLRAAANVISRAKVMVCQL-----EITPATSLEALTMARRSGVKTLF--NPAPAIADLD 186
E++ A I R+K+++ + L+A+ +A+R+ VK +F + P +
Sbjct: 129 EEVNEA--YIRRSKLLLVSGTALSKSPSREAVLKAIRLAKRNDVKVVFELDYRPYSWETP 186
Query: 187 PQ-------FYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAE 239
+ SD+ E ++L T D E L K ++++I G E
Sbjct: 187 EETAVYYSLVAEQSDIVIGTREEFDVLENRT--EKGDNDETIRYLFKHSPELIVIKHGVE 244
Query: 240 GCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAA 299
G ++ E K K + T GAGDS+ A AF A +E L + A+
Sbjct: 245 GSFAYTKAG-EAYRGYAYKTKVLKTFGAGDSY--ASAFLYALISGKGIETALKYGSASAS 301
Query: 300 VSVQAAGTQSSYPYKKDLPLTL 321
+ V + + P +++ +
Sbjct: 302 IVVSKHSSSDAMPSVEEIEALI 323
>1WYE-A nrPDB
Length = 311
Score = 202 bits (514), Expect = 2e-52, Method: Composition-based stats.
Identities = 66/321 (20%), Positives = 124/321 (38%), Gaps = 29/321 (9%)
Query: 15 VAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCK 74
+A ++ +G + + +L+ G H F G AN CV + G ++ K
Sbjct: 1 MAKLITLGEILIEFNALS-----PGPLRHVSYFEKHVAGSEANYCVAFIKQGNECGIIAK 55
Query: 75 VGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASII----VNNEGQNIIVIVAGANLL 130
VG D FG + IE L+ + A TG I V + ++I A
Sbjct: 56 VGDDEFGYNAIEWLRGQGVDVSHMKIDPSAPTGIFFIQRHYPVPLKSESIYYRKGSAGSK 115
Query: 131 LNTEDLRA----AANVISRAKVMVCQLEITPATSLEALTMARRSGVKT-----LFNPAPA 181
L+ ED+ +A+++ + + + +A +A T L++ A
Sbjct: 116 LSPEDVDEEYVKSADLVHSSGITLAISSTAKEAVYKAFEIASNRSFDTNIRLKLWSAEEA 175
Query: 182 IADLDPQFYT-LSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEG 240
++ + +++I+ G +D +AA +++++ LG +G
Sbjct: 176 KREILKLLSKFHLKFLITDTDDSKIILGE-----SDPDKAAKAFSDY-AEIIVMKLGPKG 229
Query: 241 CVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAV 300
+V + + +V D TGAGD+ G F YY +E L+ + + +
Sbjct: 230 AIVYYDGKK--YYSSGYQVPVEDVTGAGDALGGT--FLSLYYKGFEMEKALDYAIVASTL 285
Query: 301 SVQAAGTQSSYPYKKDLPLTL 321
+V G Q + P KD+ L
Sbjct: 286 NVMIRGDQENLPTTKDIETFL 306
>3H49-A nrPDB
Length = 325
Score = 201 bits (511), Expect = 4e-52, Method: Composition-based stats.
Identities = 72/323 (22%), Positives = 135/323 (41%), Gaps = 35/323 (10%)
Query: 17 AVVVVGSCMTDL--------VSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAM 68
V+ +G+ + D+ + P + + GG N+ +RLG
Sbjct: 7 DVICIGAAIVDIPLQPVSKNIFDVDSYPLE-------RIAMTTGGDAINEATIISRLGHR 59
Query: 69 TSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGAN 128
T+++ ++GKD+ G +++ ++ +I + Q T +V +G+ V +
Sbjct: 60 TALMSRIGKDAAGQFILDHCRKENIDIQSLKQDVSIDTSINVGLVTEDGERTFVTNRNGS 119
Query: 129 LL-LNTEDLRAAANVISRAKVM-VCQLEITPATSLEALT-MARRSGVKTLFNPAPAIADL 185
L LN +D+ A S+AK++ + + +P +ALT + ++ + + A I
Sbjct: 120 LWKLNIDDVDFAR--FSQAKLLSLASIFNSPLLDGKALTEIFTQAKARQMIICADMIKPR 177
Query: 186 DP-------QFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGA 238
+ + D N +EA++LTG E A L G + V+I G
Sbjct: 178 LNETLDDICEALSYVDYLFPNFAEAKLLTGKET-----LDEIADCFLACGVKTVVIKTGK 232
Query: 239 EGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIA 298
+GC + + + K + A+DT GAGD+F A F A +L + +N A
Sbjct: 233 DGCFI-KRGDMTMKVPAVAGITAIDTIGAGDNF--ASGFIAALLEGKNLRECARFANATA 289
Query: 299 AVSVQAAGTQSSYPYKKDLPLTL 321
A+SV + G + +K + L
Sbjct: 290 AISVLSVGATTGVKNRKLVEQLL 312
>5KB6-A nrPDB
Length = 363
Score = 198 bits (504), Expect = 2e-51, Method: Composition-based stats.
Identities = 70/365 (19%), Positives = 136/365 (37%), Gaps = 53/365 (14%)
Query: 1 MAASGEPQ-RQWQEEVAAVVV------VGSCMTDLVSLTSRL------PKTG-------- 39
MAA+ EP+ ++ + E + +G+ + D+ ++ + K
Sbjct: 3 MAAADEPKPKKLKVEAPQALSENVLFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDK 62
Query: 40 ------ETIHGHKFFIGFGGKGAN---QCVQAARLGAMTS-MVCKVGKDSFGNDYIENLK 89
E + K GG N + + +G D FG
Sbjct: 63 HKELFDELVKKFKVEYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAA 122
Query: 90 QNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDLRAAANV--ISRAK 147
+ + Y+ + TGT + + ++++ +A AN + L N + +A+
Sbjct: 123 DAHVDAHY-YEQNEQPTGTCAACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKAR 181
Query: 148 VMVCQ---LEITPATSLEALTMARRSG-VKTLFNPAPAIADLDPQFY----TLSDVFCCN 199
V L ++P + L+ A + V TL AP I+ + D+ N
Sbjct: 182 VYYIAGFFLTVSPESVLKVARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGN 241
Query: 200 ESEAEILT---GLTVGSAADAGEAALVLLK---RGCQVVIITLGAEGCVVLSQTEPEPKH 253
E+EA G + + A L K + + VI T G + +V ++ +
Sbjct: 242 ETEAATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFP 301
Query: 254 IPTE-KVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYP 312
+ + + + +DT GAGD+FVG F + L + + ++ A+V ++ G ++P
Sbjct: 302 VLDQNQEEIIDTNGAGDAFVG--GFLSQLVSDKPLTECIRAGHYAASVIIRRTGC--TFP 357
Query: 313 YKKDL 317
K D
Sbjct: 358 EKPDF 362
>2I6B-A nrPDB
Length = 345
Score = 198 bits (503), Expect = 3e-51, Method: Composition-based stats.
Identities = 62/314 (19%), Positives = 120/314 (38%), Gaps = 29/314 (9%)
Query: 27 DLVSLTSRLPKT-GETIHGHKFFIGFGGKGANQCVQAARLGAM-----TSMVCKVGKDSF 80
D + + + E + K GG N ++ A+ + +G D F
Sbjct: 37 DQILAEDKHKELFDELVKKFKVEYHAGGSTQN-SIKVAQWMIQQPHKAATFFGCIGIDKF 95
Query: 81 GNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDLRAAA 140
G + + + Y+ + TGT + + + +++I +A AN + L
Sbjct: 96 GEILKRKAAEAHVDAHY-YEQNEQPTGTCAACITGDNRSLIANLAAANCYKKEKHLDLEK 154
Query: 141 NVISRAKVMVCQ-----LEITPATSLEALTMARRSGVKTLFN-PAPAIADLDPQ----FY 190
N + K VC L ++P + L+ A + N AP I+ +
Sbjct: 155 NWMLVEKARVCYIAGFFLTVSPESVLKVAHHASENNRIFTLNLSAPFISQFYKESLMKVM 214
Query: 191 TLSDVFCCNESEAEILT---GLTVGSAADAGEAALVLLK---RGCQVVIITLGAEGCVVL 244
D+ NE+EA G + + L K + ++VI T G + ++
Sbjct: 215 PYVDILFGNETEAATFAREQGFETKDIKEIAKKTQALPKMNSKRQRIVIFTQGRDDTIMA 274
Query: 245 SQTEPEPKHIPTEKVK-AVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQ 303
+++E + + K +DT GAGD+FVG F + L + + ++ A++ ++
Sbjct: 275 TESEVTAFAVLDQDQKEIIDTNGAGDAFVG--GFLSQLVSDKPLTECIRAGHYAASIIIR 332
Query: 304 AAGTQSSYPYKKDL 317
G ++P K D
Sbjct: 333 RTGC--TFPEKPDF 344
>3GBU-A nrPDB
Length = 313
Score = 195 bits (496), Expect = 2e-50, Method: Composition-based stats.
Identities = 71/316 (22%), Positives = 126/316 (39%), Gaps = 35/316 (11%)
Query: 15 VAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCK 74
++ + +G + DL+S+ K F GG AN V +RLG +S++ K
Sbjct: 1 MSLIASIGELLIDLISVEEGDLKDVRL-----FEKHPGGAPANVAVGVSRLGVKSSLISK 55
Query: 75 VGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGA--NLLLN 132
VG D FG IE L + ++ T + + TG + + + ++ A N+ LN
Sbjct: 56 VGNDPFGEYLIEELSKENVDTRGIVKDEKKHTGIVFVQLKGASPSFLLYDDVAYFNMTLN 115
Query: 133 TEDLRAAANV-ISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNP----------APA 181
+ I ++ + T ++ + + S + F+
Sbjct: 116 DINWDIVEEAKIVNFGSVILARNPSRETVMKVIKKIKGSSLIA-FDVNLRLDLWRGQEEE 174
Query: 182 IADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGC 241
+ + + L+D+ +E E L V +G + ITLG +G
Sbjct: 175 MIKVLEESIKLADIVKASEEEVLYLENQGVE-------------VKGSMLTAITLGPKGF 221
Query: 242 VVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVS 301
++ +P+ V +DTTGAGD+F+ AL + L L + +N +AA+S
Sbjct: 222 RLIKN--ETVVDVPSYNVNPLDTTGAGDAFMAALLVGILKLKGLDLLKLGKFANLVAALS 279
Query: 302 VQAAGTQSSYPYKKDL 317
Q G S+ P K +L
Sbjct: 280 TQKRGAWST-PRKDEL 294
>3I3Y-A nrPDB
Length = 299
Score = 194 bits (492), Expect = 6e-50, Method: Composition-based stats.
Identities = 82/306 (26%), Positives = 134/306 (43%), Gaps = 24/306 (7%)
Query: 17 AVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVG 76
V V G+ D +PK G +IHG K GGKGANQ + +R G T ++ G
Sbjct: 4 RVYVTGNITVDETWSIPDIPKKGASIHGVKVSQDIGGKGANQAIILSRCGIETRLIAATG 63
Query: 77 KDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQN-IIVIVAGANLLLNTED 135
DS G + +K + + + T+ I+ + +G N II A A+ E
Sbjct: 64 NDSNGAWIRQQIKNEPL-MLLPDGHFNQHSDTSIILNSADGDNAIITTTAAADTFSLDEM 122
Query: 136 LRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDPQFYTLSDV 195
+ A+ ++ +++ Q + + AR G+ T+FNP+P D + L D+
Sbjct: 123 IPHMADAVA-GDILLQQGNFSLDKTRALFQYARSRGMTTVFNPSPVNPDFCH-LWPLIDI 180
Query: 196 FCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIP 255
NESEAE+L G + ++IT GA G ++ E + + P
Sbjct: 181 AVVNESEAELLQP------------------YGVKTLVITQGAAGAWLVQ--EGQRQFCP 220
Query: 256 TEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPYKK 315
+A+DTTGAGD+F+ + L ++ AA++V GT S++P +
Sbjct: 221 AVPAEALDTTGAGDTFLAVMLASALLRGVAPDALALAHASRAAAITVSRRGTLSAFPGSR 280
Query: 316 DLPLTL 321
+L L
Sbjct: 281 ELAALL 286
>4DU5-A nrPDB
Length = 336
Score = 190 bits (482), Expect = 8e-49, Method: Composition-based stats.
Identities = 71/325 (21%), Positives = 107/325 (32%), Gaps = 31/325 (9%)
Query: 10 QWQEEVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMT 69
Q V+ G M LV+ + G H F G N + ARLG
Sbjct: 21 QSMTSALDVITFGEAMMLLVA-----DRPGPLEHAEAFHKRTAGAETNVAIGLARLGLKV 75
Query: 70 SMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTAS---IIVNNEGQNIIVIVAG 126
++G DS G + + I TG + ++
Sbjct: 76 GWASRLGTDSMGRYLLAAMAAEGIDCSHVVCDATQKTGFQFKGKVTDGSDPPVEYHRKGS 135
Query: 127 ANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALT----MARRSGVKTLFNP---- 178
A + D+ A + +R AT+L A + R +G F+P
Sbjct: 136 AASHMGVADIDEAWLLSARHLHATGVFPAISATTLPAARKTMDLMRAAGRSVSFDPNLRP 195
Query: 179 -----APAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVI 233
+ D T +D E LTG T A + G ++V+
Sbjct: 196 TLWATPELMRDAINDLATRADWVLPGMEEGRFLTGETTPEG-----VARFYRQLGAKLVV 250
Query: 234 ITLGAEGCVVLSQTEPEPKHIPTEKV-KAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLN 292
+ LGAEG E + V + VDT GAGD F A+ A L + + +
Sbjct: 251 VKLGAEGAYF--DGEAGSGRVAGFPVAEVVDTVGAGDGF--AVGVISALLDGLGVPEAVK 306
Query: 293 RSNFIAAVSVQAAGTQSSYPYKKDL 317
R +I A +VQ G P + +L
Sbjct: 307 RGAWIGARAVQVLGDSEGLPTRAEL 331
>1V1S-A nrPDB
Length = 309
Score = 187 bits (474), Expect = 7e-48, Method: Composition-based stats.
Identities = 68/325 (20%), Positives = 108/325 (33%), Gaps = 42/325 (12%)
Query: 15 VAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKF-FIGFGGKGANQCVQAARLGAMTSMVC 73
+ VV G + LV P+ + G + + GG N V ARLG V
Sbjct: 1 MLEVVTAGEPLVALV------PQEPGHLRGKRLLEVYVGGAEVNVAVALARLGVKVGFVG 54
Query: 74 KVGKDSFGNDYIENLKQNDISTEF---------TYQTKDAATGTASIIVNNEGQNIIVIV 124
+VG+D G E L+ + Y + G + +G +
Sbjct: 55 RVGEDELGAMVEERLRAEGVDLTHFRRAPGFTGLYLREYLPLGQGRVFYYRKGSAGSALA 114
Query: 125 AGANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFN------- 177
GA D + + + A SL A+ A+R GV+ +
Sbjct: 115 PGAF----DPDYLEGVRFLHLSGITPALSPEARAFSLWAMEEAKRRGVRVSLDVNYRQTL 170
Query: 178 -PAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITL 236
+ D+ +E EAE+L G L V++
Sbjct: 171 WSPEEARGFLERALPGVDLLFLSEEEAELLFG----------RVEEALRALSAPEVVLKR 220
Query: 237 GAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNF 296
GA+G + V+AVD GAGD+F + L +E+ L +N
Sbjct: 221 GAKGAWAF--VDGRRVEGSAFAVEAVDPVGAGDAFAA--GYLAGAVWGLPVEERLRLANL 276
Query: 297 IAAVSVQAAGTQSSYPYKKDLPLTL 321
+ A + G PY++DL + L
Sbjct: 277 LGASVAASRGDHEGAPYREDLEVLL 301
>3IQ0-A nrPDB
Length = 330
Score = 186 bits (471), Expect = 1e-47, Method: Composition-based stats.
Identities = 66/321 (20%), Positives = 115/321 (35%), Gaps = 27/321 (8%)
Query: 15 VAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCK 74
++ V +G + ++++ P I + G A Q RLG ++
Sbjct: 3 LSKVFTIGEILVEIMASKIGQPFDQPGIWNGPY---PSGAPAIFIDQVTRLGVPCGIISC 59
Query: 75 VGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQN--IIVIVAGANLLLN 132
VG D FG+ I L + + ATG+A + +N G I I A L+
Sbjct: 60 VGNDGFGDINIHRLAADGVDIRGISVLPLEATGSAFVTYHNSGDRDFIFNIKNAACGKLS 119
Query: 133 TEDLRA----AANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNP--------AP 180
+ + + + A +A+T+ + +G F+P P
Sbjct: 120 AQHVDENILKDCTHFHIMGSSLFSFHMVDA-VKKAVTIVKANGGVISFDPNIRKEMLDIP 178
Query: 181 AIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEG 240
+ D L+D++ +E E +L+ + A L+ G + VI+ G +G
Sbjct: 179 EMRDALHFVLELTDIYMPSEGEVLLLSPHSTPE-----RAIAGFLEEGVKEVIVKRGNQG 233
Query: 241 CVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAV 300
S E H+ + V+ VD TGAGD F GA L +N A+
Sbjct: 234 ASYYSANEQ--FHVESYPVEEVDPTGAGDCFGGAWIACRQL--GFDAHRALQYANACGAL 289
Query: 301 SVQAAGTQSSYPYKKDLPLTL 321
+V G ++ +
Sbjct: 290 AVTRRGPMEGTSRLMEIETFI 310
>3UBO-A nrPDB
Length = 354
Score = 185 bits (469), Expect = 2e-47, Method: Composition-based stats.
Identities = 69/323 (21%), Positives = 118/323 (36%), Gaps = 41/323 (12%)
Query: 17 AVVVVGSCMTDLVSLTSR-LPKTGETIHGH-----------------KFFIGFGGKGANQ 58
V+ +G+ + D+++ + I G GG N
Sbjct: 7 DVLTIGNAIVDIIARCDDSFLEENGIIKGAMNLINADRAELLYSRMGPAVEASGGSAGNT 66
Query: 59 CVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQ 118
A LG + KV D G + +++ + + T + I V +G+
Sbjct: 67 AAGVASLGGRAAYFGKVADDQLGEIFTHDIRAQGVHFQTKPLDGHPPTARSMIFVTEDGE 126
Query: 119 NIIVIVAGANLLLNTEDLRAAANVISRAKVMVCQLE-ITPATS----LEALTMARRSGVK 173
+ GA + L ED+ +V++++KV + P + EA +A G +
Sbjct: 127 RSMNTYLGACVELGPEDVED--DVVAQSKVTYFEGYLWDPPRAKDAIREAARIAHAHGRE 184
Query: 174 TLFNPAPA--IADLDPQFYTL-----SDVFCCNESEAEILTGLTVGSAADAGEAALVLLK 226
T + + + +F L D+ N EA L + + AL LL
Sbjct: 185 TAMTLSDSFCVHRYRSEFLELMRSGTVDIVFANRQEALALY------ETEDFDRALELLA 238
Query: 227 RGCQVVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLS 286
R C++ +TL EG VV+ E + + + VDTTGAGD + F Y S
Sbjct: 239 RDCKLAAVTLSEEGSVVVRGAE-RVRVGASVLEQVVDTTGAGDLYAA--GFLFGYTSGRS 295
Query: 287 LEDMLNRSNFIAAVSVQAAGTQS 309
LE+ N A + + G +
Sbjct: 296 LEECSKLGNLAAGIVIGQIGPRP 318
>3PL2-A nrPDB
Length = 319
Score = 183 bits (463), Expect = 1e-46, Method: Composition-based stats.
Identities = 76/321 (23%), Positives = 126/321 (39%), Gaps = 31/321 (9%)
Query: 17 AVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVG 76
V+ +G D+ L S + F GG AN V AAR G ++++ +VG
Sbjct: 10 EVLAIGRLGVDIYPLQSGV----GLADVQSFGKYLGGSAANVSVAAARHGHNSALLSRVG 65
Query: 77 KDSFGNDYIENLKQNDISTEF--TYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTE 134
D FG + L++ + ++ T QT I ++ A LN E
Sbjct: 66 NDPFGEYLLAELERLGVDNQYVATDQTFKTPVTFCEIFPPDDFPLYFYREPKAPD-LNIE 124
Query: 135 DLRAAANVISRAKVMVCQL-----EITPATSLEALTMARRSGVKTLF--NPAPAIADLDP 187
+ + + A ++ L E + T E LT R + T+F + P +
Sbjct: 125 SADVSLDDVREADILWFTLTGFSEEPSRGTHREILT-TRANRRHTIFDLDYRPMFWESPE 183
Query: 188 Q-------FYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEG 240
+ S V N+ E EI G T + A LL+RG ++ I+ G +G
Sbjct: 184 EATKQAEWALQHSTVAVGNKEECEIAVGET-----EPERAGRALLERGVELAIVKQGPKG 238
Query: 241 CVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAV 300
V++ T+ E +P V ++ GAGD+F GAL LE +L +N A+
Sbjct: 239 --VMAMTKDETVEVPPFFVDVINGLGAGDAFGGALCH--GLLSEWPLEKVLRFANTAGAL 294
Query: 301 SVQAAGTQSSYPYKKDLPLTL 321
++ P ++ +L
Sbjct: 295 VASRLECSTAMPTTDEVEASL 315
>4N08-A nrPDB
Length = 348
Score = 181 bits (458), Expect = 4e-46, Method: Composition-based stats.
Identities = 62/295 (21%), Positives = 111/295 (37%), Gaps = 28/295 (9%)
Query: 45 HKFFIGFGGKGANQC-----VQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTY 99
GG G N +Q A G + V + D +G E + I +
Sbjct: 58 PNVRYVPGGSGLNVARVAQWMQQAYKGKFVTYVGCIADDRYGKVLKEAAEHEGIVMAVEH 117
Query: 100 QTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDLRAAA--NVISRAKVMVCQ---LE 154
TK A +G ++ + + + ++ + AN L++E +R+ A + +++ L
Sbjct: 118 TTK-AGSGACAVCITGKERTLVADLGAAN-HLSSEHMRSPAVVRAMDESRIFYFSGFTLT 175
Query: 155 ITPATSLEALTMARR-SGVKTLFNPAPAIADLDP----QFYTLSDVFCCNESEAEILTGL 209
+ L+A AR G+ + AP I + +D+ N EA+ +
Sbjct: 176 VDVNHVLQACRKAREVDGLFMINLSAPFIMQFFSAQLGEVLPYTDIIVANRHEAKEFANM 235
Query: 210 T------VGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPT-EKVKAV 262
V A + + +VV+ T E V+ ++ E +P ++ K +
Sbjct: 236 MKWDTDCVEEIARRAVSEVPYTGTKGRVVVFTRDIESTVLATKDGVETVPVPQLDQDKVI 295
Query: 263 DTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPYKKDL 317
D GAGD+F+G F AY L ++ A +Q G S+P K
Sbjct: 296 DMNGAGDAFMG--GFLSAYAVGKDLRRCCETGHYTAQEVIQRDGC--SFPEKPSF 346
>2RBC-A nrPDB
Length = 343
Score = 180 bits (457), Expect = 6e-46, Method: Composition-based stats.
Identities = 69/304 (22%), Positives = 119/304 (39%), Gaps = 11/304 (3%)
Query: 16 AAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKV 75
V+ VG+ + D + + +PK + ++ G ++ R+G S+ V
Sbjct: 30 KHVLCVGAAVLDTLFRVADMPKGEGKVLPYEVLQIAEGMASSAAYAVHRMGGRASLWGAV 89
Query: 76 GKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTED 135
G D G + +L ++ I T A + ++II++N G+ +IV L +
Sbjct: 90 GDDETGTRILRDLSESGIDTSGMTVAPGARSALSTIIIDNRGERLIVPFYDHRLH--EKK 147
Query: 136 LRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDPQFYTLSDV 195
I+ ++ + P +L+ LT+AR G + + A + +
Sbjct: 148 RACTPEDIALFDAVLVDVRW-PELALDVLTVARALGKPAILDGDVAPVETLEGLAPAATH 206
Query: 196 FCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVI-ITLGAEGCVVLSQTEPEPKHI 254
+E A LTGL + VL R Q I +T G GC +P
Sbjct: 207 IVFSEPAATRLTGLET-----VKDMLPVLHARYPQTFIAVTAGPAGCWWTEADDPTVHFQ 261
Query: 255 PTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPYK 314
T +V+AVDT AGD F G F LA + + S+ AA+ G + P +
Sbjct: 262 TTMQVEAVDTLAAGDIFHGT--FALAMAEGMQSRAAVRLSSVAAALKCTVFGGRIGAPTR 319
Query: 315 KDLP 318
++
Sbjct: 320 EETE 323
>4LC4-A nrPDB
Length = 352
Score = 179 bits (455), Expect = 1e-45, Method: Composition-based stats.
Identities = 70/324 (21%), Positives = 122/324 (37%), Gaps = 43/324 (13%)
Query: 17 AVVVVGSCMTDLVSLTSR----------------LPKTGETIHGH--KFFIGFGGKGANQ 58
V+ VG+ + D++S + + E ++ GG N
Sbjct: 27 DVLTVGNAIVDIISRCNDQFLIDNQITKAAMNLIDAERAELLYSRMGPALEASGGSAGNT 86
Query: 59 CVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQ 118
A LG + V D G+ + +++ + + + T + I V +G+
Sbjct: 87 AAGVANLGGKAAYFGNVAADQLGDIFTHDIRAQGVHYQTKPKGAFPPTARSMIFVTEDGE 146
Query: 119 NIIVIVAGANLLLNTEDLRAAANVISRAKVMVCQLE-ITPATSLEAL----TMARRSGVK 173
+ GA + L ED+ A +V++ AKV + P + EA+ +A + G +
Sbjct: 147 RSMNTYLGACVELGPEDVEA--DVVADAKVTYFEGYLWDPPRAKEAILDCARIAHQHGRE 204
Query: 174 TLFNPAPA--IADLDPQFYTL-----SDVFCCNESEAEILTGLTVGSAADAGEAALVLLK 226
+ + + +F L D+ N EA L D E AL +
Sbjct: 205 MSMTLSDSFCVDRYRGEFLDLMRSGKVDIVFANRQEALSLY------QTDDFEEALNRIA 258
Query: 227 RGCQVVIITLGAEGCVVLSQTEPEPKHIPTEKV-KAVDTTGAGDSFVGALAFYLAYYPNL 285
C++ +T+ G V+L E ++ ++ + VDTTGAGD F A F Y
Sbjct: 259 ADCKIAAVTMSENGAVILKGRER--YYVNAIRIREVVDTTGAGDLF--ASGFLYGYTQGR 314
Query: 286 SLEDMLNRSNFIAAVSVQAAGTQS 309
SLED A + +Q G +
Sbjct: 315 SLEDCGKLGCLAAGIVIQQIGPRP 338
>3LHX-A nrPDB
Length = 319
Score = 178 bits (452), Expect = 2e-45, Method: Composition-based stats.
Identities = 64/326 (19%), Positives = 106/326 (32%), Gaps = 49/326 (15%)
Query: 16 AAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARL----GAMTSM 71
+ V+G CM +L + G GFGG N V AR
Sbjct: 5 KKIAVIGECMIEL------------SEKGADVKRGFGGDTLNTSVYIARQVDPAALTVHY 52
Query: 72 VCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIV---AGAN 128
V +G DSF ++ ++ T T + ++ G I ++ G+ A A
Sbjct: 53 VTALGTDSFSQQMLDAWHGENVDTSLTQRMENRLPGLYYIETDSTGERTFYYWRNEAAAK 112
Query: 129 LLLNTEDLRAAANVISRAKVMVCQL-------EITPATSLEALTMARRSGVKTLFN---- 177
L +E A ++ + + L L R G K +F+
Sbjct: 113 FWLASEQSAAICEELANFDYLYLSGISLAILSPTSREKLLSLLRECRAKGGKVIFDNNYR 172
Query: 178 -----PAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVV 232
+ Q +D+ + + L G + G + V
Sbjct: 173 PRLWASKEETQQVYQQMLECTDIAFLTLDDEDALWGQ-----QPVEDVIARTHNAGVKEV 227
Query: 233 IITLGAEGCVVLSQTEPEPKHIPT---EKVKAVDTTGAGDSFVGALAFYLAYYPNLSLED 289
++ GA+ C+V S +P K K +DTT AGDSF + S E+
Sbjct: 228 VVKRGADSCLV-SIAGEALVDVPAVKLPKEKVIDTTAAGDSFSA--GYLAVRLTGGSAEN 284
Query: 290 MLNRSNFIAAVSVQAAGT---QSSYP 312
R + A+ +Q G + + P
Sbjct: 285 AAKRGHLTASTVIQYRGAIIPREAMP 310
>4WJM-A nrPDB
Length = 312
Score = 178 bits (451), Expect = 3e-45, Method: Composition-based stats.
Identities = 67/315 (21%), Positives = 111/315 (35%), Gaps = 37/315 (11%)
Query: 18 VVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGF-GGKGANQCVQAARLGAMTSMVCKVG 76
++ G + D++ ET G F F GG N + RLG T +
Sbjct: 8 ILCCGEALIDML--------PRETTGGETAFQPFAGGSVFNTAIALGRLGVPTGFFSGIS 59
Query: 77 KDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDL 136
D FG+ + L ++++ F + T +V+ + + A +L+ D+
Sbjct: 60 SDFFGDVLRDTLARSNVDYSFAAISNRPTTLAFVRLVDGQARYAFYDENTAGRMLSRNDM 119
Query: 137 RAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLD---------- 186
IS L P S+ +AR + + +F A+L
Sbjct: 120 PYVDETISAMLFGCISLISEPCGSVYETLLAREAPNRVMFLDPNIRANLITVRKTHLTRM 179
Query: 187 PQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQ 246
+ L+D+ ++ + + G E A LK G ++V+IT GA G V +
Sbjct: 180 KRMIALADIVKLSDEDLDWF-----GEKGSHDEIAAEWLKLGPKLVVITKGAHGAVAYTN 234
Query: 247 TEPEPKHIPTEKVKAVDTTGAGDSFVGALAF-----------YLAYYPNLSLEDMLNRSN 295
+P KV VDT GAGD+ + LA + +
Sbjct: 235 H--ATVPVPGVKVDVVDTVGAGDTVNAGILASLHSQGLLTKDALANLSEDQIHSAVALGV 292
Query: 296 FIAAVSVQAAGTQSS 310
AAV+V AG
Sbjct: 293 RAAAVTVSRAGANPP 307
>3LJS-A nrPDB
Length = 338
Score = 172 bits (435), Expect = 2e-43, Method: Composition-based stats.
Identities = 70/329 (21%), Positives = 126/329 (38%), Gaps = 38/329 (11%)
Query: 16 AAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKV 75
++ G + D+++ L K G F GG AN V ARLG V +
Sbjct: 5 KTILCFGEALIDMLA--QPLVKKG---MPRAFLQCAGGAPANVAVAVARLGGAVQFVGML 59
Query: 76 GKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIV--AGANLLLNT 133
G D FG+ ++ + + T+ +T A T A + ++ G+ A+LL
Sbjct: 60 GSDMFGDFLFDSFAEAGVVTDGIVRTSTAKTALAFVALDAHGERSFSFYRPPAADLLFRV 119
Query: 134 EDLRAAANVISRAKVMVCQLEITP----ATSLEALTMARRSGVKTLFN------PAPAIA 183
E + A + C +T + E + A+ +G F+ P
Sbjct: 120 EHFQDA-SFSDALIFHACSNSMTDADIAEVTFEGMRRAQAAGAIVSFDLNFRPMLWPNGE 178
Query: 184 DLDPQFY---TLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEG 240
+ + + +L+DV + E + L AADA L + Q++++T A
Sbjct: 179 NPASRLWKGLSLADVVKLSSEELDYLANTL---AADANAVIQQLWQGRAQLLLVTDAA-- 233
Query: 241 CVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAY------------YPNLSLE 288
V T +PT +V+ D+ AGD+FVG + + A + S+
Sbjct: 234 GPVHWYTRTAGGEVPTFRVQVQDSNAAGDAFVGGMLYTFAQQFDDAAALIDFCHDPESIV 293
Query: 289 DMLNRSNFIAAVSVQAAGTQSSYPYKKDL 317
L + + A++V G ++ P ++
Sbjct: 294 STLRFAAAVGALAVTRQGAFTAMPMLSEV 322
>2HW1-A nrPDB
Length = 298
Score = 170 bits (431), Expect = 7e-43, Method: Composition-based stats.
Identities = 61/306 (19%), Positives = 117/306 (38%), Gaps = 41/306 (13%)
Query: 14 EVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVC 73
E ++ VG + D++SL + PK I GG +N C + LGA + +
Sbjct: 2 EEKQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMG 61
Query: 74 KVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNT 133
+ + +++L++ + +T + A++I+N +G+ +L
Sbjct: 62 SMAPGHVADFVLDDLRRYSVDLRYTVFQTTGSVPIATVIINE--------ASGSRTILYY 113
Query: 134 EDLRAAANVISRAKVMVCQ---LEITPATSLEALTMARRSGVKTLFNPAP-----AIADL 185
+ + KV + Q + I + E + M +R P ++
Sbjct: 114 DRSLPDVSATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVE 173
Query: 186 DP-----QFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVII------ 234
P Q + DV ++ A+ L SA +A +++G +V
Sbjct: 174 KPREELFQLFGYGDVVFVSKDVAKHL---GFQSAEEALRGLYGRVRKGAVLVCAWAEEGA 230
Query: 235 -TLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNR 293
LG +G ++ S P P + VDT GAGD+F ++ F L+ S+++ L
Sbjct: 231 DALGPDGKLLHSDAFPPP--------RVVDTLGAGDTFNASVIFSLS--QGRSVQEALRF 280
Query: 294 SNFIAA 299
+A
Sbjct: 281 GCQVAG 286
>3LOO-A nrPDB
Length = 365
Score = 167 bits (423), Expect = 6e-42, Method: Composition-based stats.
Identities = 60/302 (19%), Positives = 119/302 (39%), Gaps = 26/302 (8%)
Query: 28 LVSLTSRLPKTGETIHGHKFFIGFGGKGAN---QCVQAARLGAMTSMVCKVGKDSFGNDY 84
+++ +P E I ++ GG N + VG+D +
Sbjct: 56 ILAEEKHMPMYQELIEKYQAEYIAGGSVQNSLRVAQWILQRPRTAIFFGCVGQDEYARIL 115
Query: 85 IENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDLRAAAN--V 142
E N ++ ++ ++ + TGT +++V +++ +A AN E LR+ N
Sbjct: 116 EERATSNGVNVQYQ-RSATSPTGTCAVLVTGTQRSLCANLAAAND-FTPEHLRSDGNRAY 173
Query: 143 ISRAKVMVCQLE---ITPATSLEALTMARRSGVKTLFN-PAPAIADLD----PQFYTLSD 194
+ A+ ++ ++L A +G + N AP + + + D
Sbjct: 174 LQGAQFFYVSGFFFTVSFESALSVAKEAAATGRMFMMNLSAPFVPQFYKNNLEEIFPYVD 233
Query: 195 VFCCNESEAEILT---GLTVGSAADAGEAALVLLK---RGCQVVIITLGAEGCVVLSQTE 248
V NE+EA L + G+ L K + ++VIIT G++ +++
Sbjct: 234 VLFGNETEAIALAKEFNYGTEDLREIGKRIAALPKENGKRKRIVIITQGSDPVLLIEAGT 293
Query: 249 PEPKHIPTEKV---KAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAA 305
+ P +K+ + VDT GAGD+FVG F + +++ + + A +Q +
Sbjct: 294 DNVREFPVQKLAPEQMVDTNGAGDAFVG--GFLAQLLQSRTVDVCIKCGIWAAREIIQRS 351
Query: 306 GT 307
G
Sbjct: 352 GC 353
>2VAR-A nrPDB
Length = 313
Score = 166 bits (420), Expect = 1e-41, Method: Composition-based stats.
Identities = 59/322 (18%), Positives = 110/322 (34%), Gaps = 29/322 (9%)
Query: 15 VAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCK 74
+ V+ +G + S G + F G N C+ R S++ +
Sbjct: 1 MVDVIALGEPLIQFNSF-----NPGPLRFVNYFEKHVAGSELNFCIAVVRNHLSCSLIAR 55
Query: 75 VGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASII----VNNEGQNIIVIVAGANLL 130
VG D FG + IE + I T ++ TG I + + + + A
Sbjct: 56 VGNDEFGKNIIEYSRAQGIDTSHIKVDNESFTGIYFIQRGYPIPMKSELVYYRKGSAGSR 115
Query: 131 LNTEDLRA----AANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNP--APAIAD 184
L+ ED+ + ++ + + + ++A +A+ + T P ++
Sbjct: 116 LSPEDINENYVRNSRLVHSTGITLAISDNAKEAVIKAFELAKSRSLDTNIRPKLWSSLEK 175
Query: 185 LDPQFYTL-----SDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAE 239
++ +V + + +IL D EA + G +V++ LG++
Sbjct: 176 AKETILSILKKYDIEVLITDPDDTKILL-----DVTDPDEAYRKYKELGVKVLLYKLGSK 230
Query: 240 GCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAA 299
G + K KV D TGAGD+ G F Y +E L +
Sbjct: 231 GAIAYKDNVKAFKD--AYKVPVEDPTGAGDAMAGT--FVSLYLQGKDIEYSLAHGIAAST 286
Query: 300 VSVQAAGTQSSYPYKKDLPLTL 321
+ + G P +D L
Sbjct: 287 LVITVRGDNELTPTLEDAERFL 308
>3GO6-A nrPDB
Length = 310
Score = 163 bits (413), Expect = 8e-41, Method: Composition-based stats.
Identities = 85/296 (28%), Positives = 118/296 (39%), Gaps = 31/296 (10%)
Query: 15 VAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCK 74
V VVGS DL + LP+ GET+ GGKGANQ V AAR GA
Sbjct: 19 APRVCVVGSVNMDLTFVVDALPRPGETVLAASLTRTPGGKGANQAVAAARAGAQVQFSGA 78
Query: 75 VGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTE 134
G D +L+ N + + T T +GTA I+V+ +N +++ GAN L
Sbjct: 79 FGDDPAAAQLRAHLRANAVGLDRTV-TVPGPSGTAIIVVDASAENTVLVAPGANAHLTP- 136
Query: 135 DLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLD--PQFYTL 192
+ ++ V++ QLEI AT+L A A+ + + N +PA D +
Sbjct: 137 ----VPSAVANCDVLLTQLEIPVATALAAARAAQSADAVVMVNASPAGQDRSSLQDLAAI 192
Query: 193 SDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPK 252
+DV NE EA +ITLG G +
Sbjct: 193 ADVVIANEHEANDWPSPPTH-------------------FVITLGVRGARYVGADG--VF 231
Query: 253 HIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLE--DMLNRSNFIAAVSVQAAG 306
+P V VDT GAGD F G LA P E L R+ A++ +G
Sbjct: 232 EVPAPTVTPVDTAGAGDVFAGVLAANWPRNPGSPAERLRALRRACAAGALATLVSG 287
>2QHP-A nrPDB
Length = 296
Score = 161 bits (407), Expect = 3e-40, Method: Composition-based stats.
Identities = 62/274 (22%), Positives = 109/274 (39%), Gaps = 16/274 (5%)
Query: 49 IGFGGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGT 108
GG AN ++ G + +V VG D G++ +E K+ + + + D TGT
Sbjct: 21 KKIGGAPANFAYHVSQFGFDSRVVSAVGNDELGDEIMEVFKEKQLKNQI--ERVDYPTGT 78
Query: 109 ASIIVNNEGQNIIVI---VAGANLLLNTEDLRAAANVISRAKVMVCQ-LEITPATSLEAL 164
+ +++EG I VA N+ E R A N + + Q E++ AT L
Sbjct: 79 VQVTLDDEGVPCYEIKEGVAWDNIPFTDELKRLALNTRAVCFGSLAQRNEVSRATINRFL 138
Query: 165 -TMARRSGVKTLFNPAPA----IADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGE 219
TM G +F+ ++ + + ++ N+ E ++ + D +
Sbjct: 139 DTMPDIDGQLKIFDINLRQDFYTKEVLRESFKRCNILKINDEELVTISRMFGYPGIDLQD 198
Query: 220 AALVLL-KRGCQVVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFY 278
+LL K +++I+T G G V + + P KV DT GAGDSF A
Sbjct: 199 KCWILLAKYNLKMLILTCGINGSYVFTPGVVSFQETP--KVPVADTVGAGDSFTAAFC-- 254
Query: 279 LAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYP 312
+ S+ + + ++A +G P
Sbjct: 255 ASILNGKSVPEAHKLAVEVSAYVCTQSGAMPELP 288
>3NCA-A nrPDB
Length = 313
Score = 159 bits (401), Expect = 2e-39, Method: Composition-based stats.
Identities = 60/305 (19%), Positives = 111/305 (36%), Gaps = 43/305 (14%)
Query: 16 AAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKV 75
+ ++ VG + D++SL + PK I GG +N C + LGA + + +
Sbjct: 19 SQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSM 78
Query: 76 GKDSFGNDYIENLKQNDISTEFTYQTKDAATG-TASIIVNNEGQNIIVIVAGANLLLNTE 134
+ + + ++ + T + II N+ G IV+ +
Sbjct: 79 APGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLH---------D 129
Query: 135 DLRAAANVISRAKVMVCQ---LEITPATSLEALTMARRSGVKTLFNPAP-----AIADLD 186
+ KV + Q + I + E + M +R P ++
Sbjct: 130 TSLPDVSATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEK 189
Query: 187 P-----QFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVII------- 234
P Q + DV ++ A+ L SA +A +++G +V
Sbjct: 190 PREELFQLFGYGDVVFVSKDVAKHL---GFQSAEEALRGLYGRVRKGAVLVCAWAEEGAD 246
Query: 235 TLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRS 294
LG +G ++ S P P + VDT GAGD+F ++ F L+ S+++ L
Sbjct: 247 ALGPDGKLLHSDAFPPP--------RVVDTLGAGDTFNASVIFSLS--QGRSVQEALRFG 296
Query: 295 NFIAA 299
+A
Sbjct: 297 CQVAG 301
>2NWH-A nrPDB
Length = 317
Score = 158 bits (398), Expect = 5e-39, Method: Composition-based stats.
Identities = 77/311 (24%), Positives = 126/311 (40%), Gaps = 23/311 (7%)
Query: 14 EVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVC 73
+ ++V+G D + G + G GG G N +RLG ++
Sbjct: 2 HMKKILVLGGAHIDRRGMIETETAPGASNPGSWMEE-AGGGGFNAARNLSRLGFEVRIIA 60
Query: 74 KVGKDSFGNDYIENLKQNDI-STEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLL-- 130
G D G E +Q + T FT+ + + TA + + N+++ +A +L
Sbjct: 61 PRGGDVTGEVVAEAARQAGVEDTPFTFLDRRTPSYTAILERDG---NLVIALADMDLYKL 117
Query: 131 LNTED--LRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTL--FNPAPAIADLD 186
+RA I + ++C + P +L AL + R+ K L +PA A
Sbjct: 118 FTPRRLKVRAVREAIIASDFLLCDANL-PEDTLTALGLIARACEKPLAAIAISPAKAVKL 176
Query: 187 PQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQ 246
D+ NE+EA LTG T + D +L K G ++T GA V +
Sbjct: 177 KAALGDIDILFMNEAEARALTGETAENVRDWPN---ILRKAGLSGGVVTRGASEVVAFNG 233
Query: 247 TEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAG 306
TE H P + + D TGAGD+ A + A ++ + L + AA++V
Sbjct: 234 TEKAILHPPLIR-EVKDVTGAGDAM--ASGYLAAIAEGKTIREALRQGAAAAAITV---- 286
Query: 307 TQSSYPYKKDL 317
QSS+ +DL
Sbjct: 287 -QSSFATSQDL 296
>3N1C-A nrPDB
Length = 309
Score = 148 bits (373), Expect = 3e-36, Method: Composition-based stats.
Identities = 60/281 (21%), Positives = 108/281 (38%), Gaps = 21/281 (7%)
Query: 38 TGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEF 97
+ GG G N A LG + + G + G + L ++
Sbjct: 24 PEGKLRCTAPVFEPGGGGINVARAIAHLGGSATAIFPAG-GATGEHLVSLLADENVPVA- 81
Query: 98 TYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDLRAAANV---ISRAKVMVCQLE 154
T + KD + V G+ ++ GA LN ++ R I ++V
Sbjct: 82 TVEAKDWTRQNLHVHVEASGEQYRFVMPGA--ALNEDEFRQLEEQVLEIESGAILVISGS 139
Query: 155 ITPATSLEALTM----ARRSGVKTLFNPAPAIADLDPQFYTLSDV--FCCNESEAEILTG 208
+ P LE LT A++ G++ + + + + + ++ N+ E L
Sbjct: 140 LPPGVKLEKLTQLISAAQKQGIRCIVDSS---GEALSAALAIGNIELVKPNQKELSALVN 196
Query: 209 LTVGSAADAGEAALVLLKRG-CQVVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGA 267
+ D +AA ++ G + V+++LG +G + + + VK+ T GA
Sbjct: 197 RELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGV--DSENCIQVVPPPVKSQSTVGA 254
Query: 268 GDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQ 308
GDS VGA+ LA N SLE+M+ + + GT+
Sbjct: 255 GDSMVGAMTLKLA--ENASLEEMVRFGVAAGSAATLNQGTR 293
>2AA0-A nrPDB
Length = 383
Score = 127 bits (320), Expect = 5e-30, Method: Composition-based stats.
Identities = 69/349 (19%), Positives = 113/349 (32%), Gaps = 58/349 (16%)
Query: 17 AVVVVGSCMTDLVSLTSR-------LPKTGETIHGHKFFIG------------FGGKGAN 57
V +G+ + DLV+ L + T+ + GG N
Sbjct: 34 RVFAIGNPILDLVAEVPSSFLDEFFLKRGDATLATPEQMRIYSTLDQFNPTSLPGGSALN 93
Query: 58 QCVQAARL---GAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVN 114
+L + +G D G E + ++T F +TG ++++N
Sbjct: 94 SVRVVQKLLRKPGSAGYMGAIGDDPRGQVLKELCDKEGLATRFMV-APGQSTGVCAVLIN 152
Query: 115 NEGQNIIVIVAGANLLLN-TEDLRAAANVISRAKVMVCQLEITPATSLEALTMARR--SG 171
+ + + GA ED A+ L TP +LE A +
Sbjct: 153 EK-ERTLCTHLGACGSFRLPEDWTTFASGALIFYATAYTLTATPKNALEVAGYAHGIPNA 211
Query: 172 VKTLFNPAPAIADLDPQ----FYTLSDVFCCNESEAEILTGL--------------TVGS 213
+ TL AP +L +++ NE E L +
Sbjct: 212 IFTLNLSAPFCVELYKDAMQSLLLHTNILFGNEEEFAHLAKVHNLVAAEKTALSTANKEH 271
Query: 214 AADAGEAALVLLKRGC-----QVVIITLGAEGCVVLSQTEPEPKHIPT------EKVKAV 262
A + AL LL G ++V++T G + QT + K V
Sbjct: 272 AVEVCTGALRLLTAGQNTSATKLVVMTRGHNPVIAAEQTADGTVVVHEVGVPVVAAEKIV 331
Query: 263 DTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSY 311
DT GAGD+FVG F A +++ + N A +Q G S+
Sbjct: 332 DTNGAGDAFVG--GFLYALSQGKTVKQCIMCGNACAQDVIQHVGFSLSF 378
>3UQ9-A nrPDB
Length = 372
Score = 116 bits (289), Expect = 2e-26, Method: Composition-based stats.
Identities = 58/302 (19%), Positives = 110/302 (36%), Gaps = 26/302 (8%)
Query: 28 LVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQA---ARLGAMTSMVCKVGKDSFGNDY 84
+++ + E K GG N + + S V +G D G
Sbjct: 59 VLAEEKHMTIYDEIQKKKKLNYIAGGATLNTVKMIQWIIQKPFVCSYVGCIGADIQGKYI 118
Query: 85 IENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDLRAA--ANV 142
+ D+ TEF + TG +++V+ + +V GA L+ + ++
Sbjct: 119 KNDCSALDLVTEFQIAEEPLMTGKVAVLVSEK-LRSMVTYLGAACDLSLAHIEQPHVWSL 177
Query: 143 ISRAKVMVCQLEITP---ATSLEALTMARRSGVKTLFN-PAPAIADLD----PQFYTLSD 194
+ +A+V + L+ + + FN AP ++ + + + S+
Sbjct: 178 VEKAQVYYIAGFVINTCYEGMLKIAKHSLENEKLFCFNLSAPFLSQFNTKEVDEMISYSN 237
Query: 195 VFCCNESEAE-------ILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQT 247
+ NESEAE +L +A + K+ ++VIIT G + +
Sbjct: 238 IVFGNESEAEAYGEVHGLLEDTVHATARYIADLPFADGKKRKRLVIITRGKNPLLYTDSS 297
Query: 248 EPEPKHIPTEK---VKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQA 304
+ E E+ + +DT GAGD+F F Y + L+ + AA +
Sbjct: 298 DSEIHQFMVEQFKDDQIIDTNGAGDAFAA--GFIADYIRGKPMITSLHAAVKAAAYIICR 355
Query: 305 AG 306
+G
Sbjct: 356 SG 357
>2ABQ-A nrPDB
Length = 306
Score = 115 bits (287), Expect = 3e-26, Method: Composition-based stats.
Identities = 57/300 (19%), Positives = 107/300 (35%), Gaps = 25/300 (8%)
Query: 26 TDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYI 85
D + + G + GGKG N RLG T + +G G
Sbjct: 11 IDYIVQVENF-QQGVVNRSERDRKQPGGKGINVSRVLKRLGHETKALGFLG-GFTGAYVR 68
Query: 86 ENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDLRAAANVI-- 143
L++ +I F D I V +G+ + A L+ E ++A +
Sbjct: 69 NALEKEEIGLSFIEVEGDTR-----INVKIKGKQETELNGTAPLIKK-EHVQALLEQLTE 122
Query: 144 -SRAKVMVCQLEIT---PATSLEALT-MARRSGVKTLFNPAPAIADLDPQFYTLSDVFCC 198
+ V+V + P T ++T +A+ G + + L
Sbjct: 123 LEKGDVLVLAGSVPQAMPQTIYRSMTQIAKERGAFVAVDTS--GEALHEVLAAKPSFIKP 180
Query: 199 NESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPTEK 258
N E L + S DA L+ G + ++++ +G + S ++P+ +
Sbjct: 181 NHHELSELVSKPIASIEDAIPHVQRLIGEGIESILVSFAGDGALFASAEGMFHVNVPSGE 240
Query: 259 VKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPYKKDLP 318
V+ ++ GAGDS V F A SLED + + + + + G + ++++
Sbjct: 241 VR--NSVGAGDSVVA--GFLAALQEGKSLEDAVPFAVAAGSATAFSDG----FCTREEVE 292
>3KD6-A nrPDB
Length = 313
Score = 114 bits (285), Expect = 6e-26, Method: Composition-based stats.
Identities = 59/301 (19%), Positives = 111/301 (36%), Gaps = 34/301 (11%)
Query: 17 AVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARL-GAMTSMVCKV 75
+++V+GS D + + ++ T+ GG + A+ MV V
Sbjct: 4 SLLVIGSLAFDDI--ETPFGRSDNTL---------GGSSTYIALSASYFTDEPIRMVGVV 52
Query: 76 GKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNT-- 133
G D FG ++ + L +I T +D T + + + + + LN
Sbjct: 53 GSD-FGKEHFDLLHAKNIDTRGIQVIEDGKTFRWAGRYHYD----MNTRDTLDTQLNVFA 107
Query: 134 EDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKT---LFNPAPAIADLDPQFY 190
E +K VC I P L+ L + + + +
Sbjct: 108 EFDPHVPQYYRDSKF-VCLGNIDPELQLKVLDQIDDPKLVVCDTMNFWIEGKPEELKKVL 166
Query: 191 TLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPE 250
DVF N+SEA +L+G + + A ++ + G + +II G G ++ +
Sbjct: 167 ARVDVFIVNDSEARLLSG-----DPNLVKTARIIREMGPKTLIIKKGEHGALLFTDNG-- 219
Query: 251 PKHIPTEKVKAV-DTTGAGDSFVGALAFYLAY---YPNLSLEDMLNRSNFIAAVSVQAAG 306
P ++++ D TGAGD+F G +LA + + + +A+ V+ G
Sbjct: 220 IFAAPAFPLESIYDPTGAGDTFAGGFIGHLARCGNTSEAEMRKAVLYGSAMASFCVEQFG 279
Query: 307 T 307
Sbjct: 280 P 280
>3B1N-A nrPDB
Length = 326
Score = 113 bits (283), Expect = 1e-25, Method: Composition-based stats.
Identities = 54/318 (16%), Positives = 106/318 (33%), Gaps = 34/318 (10%)
Query: 15 VAAVVVVGSCMTDLVSLTSRLPKT----------GETIHGHKFFIGFGGKGANQCVQAAR 64
+A ++ GS D + + + FGG N
Sbjct: 1 MATLIC-GSIAYDNIMTFEGRFREHILPDQVHLINLSFLVPTMRREFGGCAGNIAYALNL 59
Query: 65 LGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIV 124
LG M+ +G Y++ + +S E+ D + A I + + I
Sbjct: 60 LGGDARMMGTLGA-VDAQPYLDRMDALGLSREYVRVLPDTYSAQAMITTDLDNNQITAFH 118
Query: 125 AGANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIAD 184
GA + + A ++ + ++ ++GV +F+P +
Sbjct: 119 PGAMMQSHVNHAGEAKDIK-----LAIVGPDGFQGMVQHTEELAQAGVPFIFDPGQGLPL 173
Query: 185 LD----PQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEG 240
D + L+ N+ EA+++ T S + Q +IIT G G
Sbjct: 174 FDGATLRRSIELATYIAVNDYEAKLVCDKTGWSEDEIAS--------RVQALIITRGEHG 225
Query: 241 CVVLSQTEPEPKHIPTEKVK-AVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAA 299
+ + E IP + + +D TG GD+F G L + ++ + A
Sbjct: 226 ATIRHRDGTE--QIPAVRAERVIDPTGCGDAFRGGLLY--GIEHGFDWATAGRLASLMGA 281
Query: 300 VSVQAAGTQSSYPYKKDL 317
+ + G Q+ P + ++
Sbjct: 282 LKIAHQGPQTYAPTRAEI 299
>4E84-A nrPDB
Length = 352
Score = 111 bits (276), Expect = 6e-25, Method: Composition-based stats.
Identities = 62/316 (19%), Positives = 109/316 (34%), Gaps = 29/316 (9%)
Query: 7 PQRQWQEEVAAVVVVGSCMTDLVS--LTSRL-PK-TGETIHGHKFFIGFGGKGANQCVQA 62
P + Q + V+VVG M D R+ P+ +H + GG AN A
Sbjct: 45 PVPREQLARSRVLVVGDVMLDRYWFGNVDRISPEAPVPVVHVQRQEERLGGA-ANVARNA 103
Query: 63 ARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIV 122
LG ++C VG D G +E L + + T + T ++ + Q + V
Sbjct: 104 VTLGGQAGLLCVVGCDEPGERIVELLGSSGV-TPHLERDPALPTTIKLRVLARQQQLLRV 162
Query: 123 IVAGANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEA---------LTMARRSGVK 173
++R V++ Q ++ + + AR +G
Sbjct: 163 DFEAMPTH------EVLLAGLARFDVLLPQHDVVLMSDYAKGGLTHVTTMIEKARAAGKA 216
Query: 174 TLFNPAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVI 233
L +P Y + + N +E + G A + + ++
Sbjct: 217 VLVDPKGDDWAR----YRGASLITPNRAELREVVGQWKSEDDLRARVANLRAELDIDALL 272
Query: 234 ITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNR 293
+T EG + S H P + D +GAGD+ + +A L + L D +
Sbjct: 273 LTRSEEGMTLFSAGGE--LHAPALAREVFDVSGAGDTVIATVATMLGA--GVPLVDAVVL 328
Query: 294 SNFIAAVSVQAAGTQS 309
+N A + V GT +
Sbjct: 329 ANRAAGIVVGKLGTAT 344
>6C9R-A nrPDB
Length = 337
Score = 109 bits (271), Expect = 2e-24, Method: Composition-based stats.
Identities = 59/306 (19%), Positives = 101/306 (33%), Gaps = 27/306 (8%)
Query: 18 VVVVGSCMTDLV----------SLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGA 67
+ V GS TD + L L K + + GG N LG
Sbjct: 16 IAVTGSIATDHLMRFPGRFSEQLLPEHLHKVSLSFLVDDLVMHRGGVAGNMAFAIGVLGG 75
Query: 68 MTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGA 127
++V G D DY + LK ++ + ++ A T + + + I GA
Sbjct: 76 EVALVGAAGADF--ADYRDWLKARGVNCDHVLISETAHTARFTCTTDVDMAQIASFYPGA 133
Query: 128 NLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDP 187
L + I + + +V P R+ G+ +P+ +A L
Sbjct: 134 MSEARNIKLADVVSAIGKPE-LVIIGANDPEAMFLHTEECRKLGLAFAADPSQQLARLSG 192
Query: 188 QFYTL----SDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVV 243
+ + N+ E ++L T S AD + + TLG +G +
Sbjct: 193 EEIRRLVNGAAYLFTNDYEWDLLLSKTGWSEADVMAQ--------IDLRVTTLGPKGVDL 244
Query: 244 LSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQ 303
+ + D TG GD+F F L LE + +A + ++
Sbjct: 245 VEPDGTTIHVGVVPETSQTDPTGVGDAFRA--GFLTGRSAGLGLERSAQLGSLVAVLVLE 302
Query: 304 AAGTQS 309
+ GTQ
Sbjct: 303 STGTQE 308
>4E69-A nrPDB
Length = 328
Score = 106 bits (265), Expect = 1e-23, Method: Composition-based stats.
Identities = 63/325 (19%), Positives = 103/325 (31%), Gaps = 48/325 (14%)
Query: 13 EEVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTS-- 70
+ + ++ +G CM +L + +GF G N ARL +
Sbjct: 21 QSMMHILSIGECMAEL----------APADLPGTYRLGFAGDTFNTAWYLARLRPESRIS 70
Query: 71 MVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAG--AN 128
+G D+ + I G I + +G+ G A
Sbjct: 71 YFSAIGDDALSQQMRAAMSAAGIDGGGLRVIPGRTVGLYLITL-EQGERSFAYWRGQSAA 129
Query: 129 LLL-----NTEDLRAAANVISRAKVMVCQLEI-TPATSLEALTMARRSGVKTLFNPAPAI 182
L A A+V+ + + + L+ AT L AL AR +G F+P
Sbjct: 130 RELAGDADALAAAMARADVVYFSGITLAILDQCGRATLLRALAQARATGRTIAFDP---- 185
Query: 183 ADLDPQFY--------------TLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRG 228
+L P+ + +SD+ + + G A A + G
Sbjct: 186 -NLRPRLWAGTGEMTETIMQGAAVSDIALPSFEDEAAWFGDAGPDAT-----ADRYARAG 239
Query: 229 CQVVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLE 288
+ V++ G V Q + + VDTT AGDSF L + LE
Sbjct: 240 VRSVVVKNGPH-AVHFLQDGRRGRVPVPPVAQVVDTTAAGDSFNAGL--LDSVLAGQPLE 296
Query: 289 DMLNRSNFIAAVSVQAAGTQSSYPY 313
+ + +A VQ G P
Sbjct: 297 TAIAAAAALAGQVVQGKGALVEVPS 321
>2AFB-A nrPDB
Length = 351
Score = 106 bits (263), Expect = 2e-23, Method: Composition-based stats.
Identities = 64/324 (19%), Positives = 105/324 (32%), Gaps = 42/324 (12%)
Query: 17 AVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVG 76
VV G M L P F + +GG AN A++G V K+
Sbjct: 14 KVVTFGEIMLRL-----SPPDHKRIFQTDSFDVTYGGAEANVAAFLAQMGLDAYFVTKLP 68
Query: 77 KDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNT--- 133
+ G+ +L++ + T++ + + G + + + V+ A+ ++
Sbjct: 69 NNPLGDAAAGHLRKFGVKTDYIARGGN-RIGIYFLEIGASQRPSKVVYDRAHSAISEAKR 127
Query: 134 EDLRAAANVISRAKVMVCQLEITP-----ATSLE-ALTMARRSGVKTL--FNPAPAIADL 185
ED ++ A+ P LE AL +A GV N +
Sbjct: 128 EDFDWEK-ILDGARWFHFSGITPPLGKELPLILEDALKVANEKGVTVSCDLNYRARLWTK 186
Query: 186 DPQ------FYTLSDVFCCNESEAEILTGLTVG----------SAADAGEAALVLLKRGC 229
+ F DV NE + E + G++V A A A V K
Sbjct: 187 EEAQKVMIPFMEYVDVLIANEEDIEKVLGISVEGLDLKTGKLNREAYAKIAEEVTRKYNF 246
Query: 230 QVVIITL--GAEGCVVLSQT----EPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYP 283
+ V ITL V +P ++ VD GAGDSF GAL +
Sbjct: 247 KTVGITLRESISATVNYWSVMVFENGQPHFSNRYEIHIVDRVGAGDSFAGALIYGSLM-- 304
Query: 284 NLSLEDMLNRSNFIAAVSVQAAGT 307
+ + + + G
Sbjct: 305 GFDSQKKAEFAAAASCLKHTIPGD 328
>2JG5-A nrPDB
Length = 306
Score = 103 bits (256), Expect = 1e-22, Method: Composition-based stats.
Identities = 57/281 (20%), Positives = 106/281 (37%), Gaps = 17/281 (6%)
Query: 26 TDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYI 85
D V T+ K + GGKG N L ++ + G G I
Sbjct: 11 IDYVIFTNDF-KIDGLNRATATYKFAGGKGINVSRVLKTLDVESTALGFAG-GFPGKFII 68
Query: 86 ENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNT-EDLRAAANVIS 144
+ L + I + F +D GQ + G ++ E L +
Sbjct: 69 DTLNNSAIQSNFIEVDEDTRINVKL----KTGQETEINAPGPHITSTQFEQLLQQIKNTT 124
Query: 145 RAKVMVCQLEITPATSLEA----LTMARRSGVKTLFNPAPAIADLDPQFYTLSDVFCCNE 200
+++ + + +A + ++G K + + +A+ ++ L N+
Sbjct: 125 SEDIVIVAGSVPSSIPSDAYAQIAQITAQTGAKLVVDAEKELAESVLPYHPL--FIKPNK 182
Query: 201 SEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPTEKVK 260
E E++ TV S AD + +L+ +G Q VI++LG +G + + + P KV
Sbjct: 183 DELEVMFNTTVNSDADVIKYGRLLVDKGAQSVIVSLGGDGAIYIDKEISIKAVNPQGKV- 241
Query: 261 AVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVS 301
V+T G+GDS V + +A LS+E ++ +
Sbjct: 242 -VNTVGSGDSTVAGMVAGIA--SGLSIEKAFQQAVACGTAT 279
>3JUL-A nrPDB
Length = 320
Score = 101 bits (250), Expect = 6e-22, Method: Composition-based stats.
Identities = 55/295 (18%), Positives = 109/295 (36%), Gaps = 18/295 (6%)
Query: 23 SCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGKDSFGN 82
+ D + + +T K GGKG + ++ G + G D+ +
Sbjct: 10 NPAIDRLLFIRGELEKRKTNRVIKTEFDCGGKGLHVSGVLSKFGIKNEALGIAGSDNL-D 68
Query: 83 DYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTED--LRAAA 140
LK+ I+ +F + + ++ ++ + ++ AG + +D L+ A
Sbjct: 69 KLYAILKEKHINHDFLVEAGTSTRECFVVLSDDTNGSTMIPEAGFTVSQTNKDNLLKQIA 128
Query: 141 NVISRAKVMVCQLEITPATSL----EALTMARRSGVKTLFNPAPAIADLDPQFYTLSDVF 196
+ + ++V P +L E L + +G + + +L + D
Sbjct: 129 KKVKKEDMVVIAGSPPPHYTLSDFKELLRTVKATGAFLGCDNSGEYLNLAVEMG--VDFI 186
Query: 197 CCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPT 256
NE E + S + L ++++LGA+G + + +
Sbjct: 187 KPNEDEVIAILDEKTNSLEENIRT----LAEKIPYLVVSLGAKGSICAHNGK--LYQVIP 240
Query: 257 EKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSY 311
KV+ + TGAGD FVGA LA N+ + + L + +A V SS+
Sbjct: 241 PKVQERNDTGAGDVFVGAFIAGLAM--NMPITETLKVATGCSASKVMQQ-DSSSF 292
>2AWD-A nrPDB
Length = 323
Score = 100 bits (249), Expect = 7e-22, Method: Composition-based stats.
Identities = 56/300 (18%), Positives = 104/300 (34%), Gaps = 25/300 (8%)
Query: 18 VVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGK 77
V V + D+ L L K + GGKG N LG +G
Sbjct: 5 VTVTMNPSIDISYLLDHL-KLDTVNRTSQVTKTPGGKGLNVTRVIHDLGGDVIATGVLG- 62
Query: 78 DSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDLR 137
G LK+ +I FT ++ A + EG ++ AG ++ E++
Sbjct: 63 GFHGAFIANELKKANIPQAFTSIKEETRDSIAILH---EGNQTEILEAG--PTVSPEEIS 117
Query: 138 AAAN----VISRAKVMVCQLE----ITPATSLEALTMARRSGVKTLFNPAPAIADLDPQF 189
+I +A+++ + E + A VK L + + Q
Sbjct: 118 NFLENFDQLIKQAEIVTISGSLAKGLPSDFYQELVQKAHAQEVKVLLDTSGDSLRQVLQG 177
Query: 190 YTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKR----GCQVVIITLGAEGCVVLS 245
+ N E E L G + A L + G + ++I+LG +G + +
Sbjct: 178 PWKPYLIKPNLEELEGLLGQDFSE--NPLAAVQTALTKPMFAGIEWIVISLGKDGAI--A 233
Query: 246 QTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAA 305
+ + + ++A + G+GD+ + LA+ LA + ++L + Q
Sbjct: 234 KHHDQFYRVKIPTIQAKNPVGSGDATIAGLAYGLA--KDAPAAELLKWGMAAGMANAQER 291
>4GM6-A nrPDB
Length = 351
Score = 97.2 bits (240), Expect = 8e-21, Method: Composition-based stats.
Identities = 52/334 (15%), Positives = 108/334 (32%), Gaps = 35/334 (10%)
Query: 5 GEPQRQWQEEVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAAR 64
G +Q + VV +G + L + + I GG AN V ++
Sbjct: 14 GTENLYFQSMMKQVVTIGELLMRLSTQ-----QGIPFSQTTALDIHIGGAEANVAVNLSK 68
Query: 65 LGAMTSMVCKVGKDSFGNDYIENLKQNDISTEF---------TYQTKDAATGTASIIVNN 115
LG T + V + G +E+L ++ + T F TY + A +V +
Sbjct: 69 LGHPTRIATVVPANPIGKMAVEHLWRHQVDTAFVVEAGDRLGTYYLESGTALKAPSVVYD 128
Query: 116 EGQNIIVIVAGANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTL 175
+ + L+ L V+ + + + ++ + A+R+G+K
Sbjct: 129 RQHSSFARHKSMDWDLSE--LLKGIRVLHVSGITIALSTFWLEMVVKIIREAKRNGIKIS 186
Query: 176 FNP--------APAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSA----ADAGEAALV 223
F+ A Q L D + +A ++ + A + +
Sbjct: 187 FDMNYRAKLWELEAAKRAYQQLLPLVDYCSAGQMDAVAFFEISSETTDYYQAMHDKYPNI 246
Query: 224 LLKRGCQVVIITLGA---EGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLA 280
L + +I+ +G + E + + VD G GD++ A+
Sbjct: 247 ELFYATKRTVISASHHLLQGHLWTQGECWESEEYAIYPI--VDRVGGGDAYTAAVLH--G 302
Query: 281 YYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPYK 314
++ + + A + G + + K
Sbjct: 303 ILSEWRPDETVKFATAAAGLKHSIHGDINPFDEK 336
>3BF5-A nrPDB
Length = 306
Score = 96.0 bits (237), Expect = 2e-20, Method: Composition-based stats.
Identities = 55/294 (18%), Positives = 102/294 (34%), Gaps = 38/294 (12%)
Query: 13 EEVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMV 72
+ + + G D++ +P+ G +++ FGG N + A + +
Sbjct: 18 QGMRFLAYFGHLNIDVLISVDSIPREG-SVNVKDLRPRFGGTAGNFAIVAQKFRIPFDLY 76
Query: 73 CKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLN 132
VG + +Y+ ++ I+T + +D + I + + Q +
Sbjct: 77 SAVGMKTH-REYLAMIESMGINTGHVEKFEDESGPICYIATDGKKQVSFMHQGAMAAW-- 133
Query: 133 TEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAI----ADLDPQ 188
A + + + T L MA+ K +F+P+ I D +
Sbjct: 134 ------APQLADEYEYVHFS------TGPNYLDMAKSIRSKIIFDPSQEIHKYSKDELKK 181
Query: 189 FYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTE 248
F+ +S + N+ E + +T S+ I+T G G + +
Sbjct: 182 FHEISYMSIFNDHEYRVFREMTGLSSPKV-------------TTIVTNGERGSSLFMDGK 228
Query: 249 PEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSV 302
P + DT GAGDSF L YLA Y S+E + IA +
Sbjct: 229 K--YDFPAIP-SSGDTVGAGDSFRAGL--YLALYNRRSIEKGMIYGTIIAHHVI 277
>2Q5R-A nrPDB
Length = 330
Score = 87.5 bits (215), Expect = 6e-18, Method: Composition-based stats.
Identities = 45/282 (15%), Positives = 96/282 (34%), Gaps = 29/282 (10%)
Query: 43 HGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTK 102
+ GGKG N A++G +G G + L + + +
Sbjct: 47 RVQEVSKTAGGKGLNVTRVLAQVGEPVLASGFIG-GELGQFIAKKL--DHADIKHAFYNI 103
Query: 103 DAATGTASIIVNNEGQNIIV-------IVAGANLLLNTEDLRAAANVISRAKVMVCQLEI 155
T I++ Q I+ A + + E L ++ +
Sbjct: 104 KGETRNCIAILHEGQQTEILEQGPEIDNQEAAGFIKHFEQLLEKVEAVA------ISGSL 157
Query: 156 TPATSLEA----LTMARRSGVKTLFNPAPAIADLDPQFYTLSDVFCCNESEAEILTGLTV 211
+ + + + GV + + + A + V N SE L +
Sbjct: 158 PKGLNQDYYAQIIERCQNKGVPVILDCSGATLQTVLENPYKPTVIKPNISELYQLLNQPL 217
Query: 212 GSAADAGEAA--LVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGD 269
+ ++ + A L + G + +I++LGA+G ++ + + ++ G+GD
Sbjct: 218 DESLESLKQAVSQPLFE-GIEWIIVSLGAQGAF--AKHNHTFYRVNIPTISVLNPVGSGD 274
Query: 270 SFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSY 311
S V A + + D+L ++N + ++ Q Q+ Y
Sbjct: 275 STVA--GITSAILNHENDHDLLKKANTLGMLNAQE--AQTGY 312
>2AJR-A nrPDB
Length = 331
Score = 84.4 bits (207), Expect = 7e-17, Method: Composition-based stats.
Identities = 53/294 (18%), Positives = 105/294 (35%), Gaps = 36/294 (12%)
Query: 30 SLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENLK 89
+RL + + K + GGKG N + ++LG + VG G +E L+
Sbjct: 32 FQVNRLYRINDL---SKTQMSPGGKGINVSIALSKLGVPSVATGFVG-GYMGKILVEELR 87
Query: 90 QNDISTEFTYQTKDAATGTASIIVNNEGQNIIVI-VAGANLL-LNTED-LRAAANVISRA 146
+ + + T I++ + + I I G ++ ++ LR +S+
Sbjct: 88 KISKLITTNFVYVEGETRENIEIIDEKNKTITAINFPGPDVTDMDVNHFLRRYKMTLSKV 147
Query: 147 KVMVCQLEITPATS----LEALTMARRSGVKTLFNPAPAIADLDPQFYTLSDVFCCN-ES 201
+V I P + E + +AR GV P + + + +V +
Sbjct: 148 DCVVISGSIPPGVNEGICNELVRLARERGVFVFVEQTPRLLERIYEGPEFPNVVKPDLRG 207
Query: 202 EAEILTGLTVGSAADAGEAALVLLKRGCQVVI-------ITLGAEGCVVLSQTEPEPKHI 254
G+ + + D + A L ++ V+ I EG ++ E
Sbjct: 208 NHASFLGVDLKTFDDYVKLAEKLAEKSQVSVVSYEVKNDIVATREGVWLIRSKEE----- 262
Query: 255 PTEKVKAVDT---TGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAA 305
+DT GAGD++V + +Y + + +M F +A++
Sbjct: 263 -------IDTSHLLGAGDAYVAGMVYYFIKH-GANFLEMAKFG-FASALAATRR 307
>3KTN-A nrPDB
Length = 346
Score = 68.3 bits (165), Expect = 4e-12, Method: Composition-based stats.
Identities = 47/327 (14%), Positives = 94/327 (28%), Gaps = 46/327 (14%)
Query: 17 AVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVG 76
+ G M P+ + + F G G N A T+++ K+
Sbjct: 4 KIAAFGEVMLRFT-----PPEYLMLEQTEQLRMNFVGTGVNLLANLAHFQLETALITKLP 58
Query: 77 KDSFGNDYIENLKQNDISTEFTYQTKDAATGTAS-----------IIVNNEGQNIIVIVA 125
+ G L++ IS ++ K G+ + N Q+ I
Sbjct: 59 ANRLGEAGKAALRKLGISDQW-VGEKGDHIGSFFAEMGYGIRPTQVTYQNRHQSAFGISE 117
Query: 126 GANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFN-------- 177
+ E A +++ + + E T +L A K F+
Sbjct: 118 AKDYDF--EAFLAEVDMVHICGISLSLTEKTRDAALILAQKAHAYQKKVCFDFNYRPSLN 175
Query: 178 ---PAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKR-----GC 229
A + + D+ + + L G + L++R
Sbjct: 176 TANSALFMRQQYERILPYCDIVFGSRRDLVELLGFIPREDLEGEAQETELIQRFMSQYNL 235
Query: 230 QVVIITLGAEG-------CVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYY 282
+ T + + +Q E + + +D GAGD++ + + Y
Sbjct: 236 EWFAGTTRSHSQNQNYLSGYLYTQNE--YQQSEKRPLLNLDRIGAGDAYAAGILY--GYS 291
Query: 283 PNLSLEDMLNRSNFIAAVSVQAAGTQS 309
N SLE + + ++ G
Sbjct: 292 QNWSLEKAVTFATVNGVLAHTIQGDIP 318
>5YSQ-A nrPDB
Length = 286
Score = 60.9 bits (146), Expect = 7e-10, Method: Composition-based stats.
Identities = 42/296 (14%), Positives = 104/296 (35%), Gaps = 23/296 (7%)
Query: 28 LVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIEN 87
+++ + K + G + I +GG + ++ LG T ++ K ++
Sbjct: 1 MITFIGHVSKDVNVVDGKR-EIAYGGGVVMGAITSSLLGVKTKVITKCTREDVSKF--SF 57
Query: 88 LKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDLRAAANVISRAK 147
L+ N + F + + + ++ ++ A + + A I+
Sbjct: 58 LRDNGVEVVFLKSPRTTSIENRYGSDPDTRESFLISAADPFTESDLAFIEGEAVHINPLW 117
Query: 148 VMVCQLEITPATSLEALTMARRSGVKTLFNPAPAI----ADLDPQFYTLSDVFCCNESEA 203
++ P + + ++ + + ++ ++ D+F + EA
Sbjct: 118 YGEFPEDLIPVLRRKVMFLSADAQGFVRVPENEKLVYRDWEMKEKYLKYLDLFKVDSREA 177
Query: 204 EILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQT-EPEPKHIPTEKVKAV 262
E LTG D E+ ++ G ++++ T A G +V + + +
Sbjct: 178 ETLTGTN-----DLRESCRIIRSFGAKIILATH-ASGVIVFDGNFYEASFRSWSLEGR-- 229
Query: 263 DTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPYKKDLP 318
TG GD+ A + +S+E + + +V ++ G ++DL
Sbjct: 230 --TGRGDTCTAAFLVGF-VFKKMSIEKATKFAAAVTSVKMRHPGPL----RREDLE 278
>4S1M-A nrPDB
Length = 287
Score = 58.6 bits (140), Expect = 4e-09, Method: Composition-based stats.
Identities = 41/215 (19%), Positives = 75/215 (34%), Gaps = 27/215 (12%)
Query: 107 GTASIIVNNEGQNIIVIVAGANLLLNT----EDLRAAANVISRAKVMVCQLEITPATSLE 162
+ + +V G+ +LLN D ++ + +V + E
Sbjct: 33 SIFVLTTHLANHTGYPVVGGSGVLLNDFISIMDSLEVNHLDKDIEFLVTGYFPSSDLVYE 92
Query: 163 ALTMARR--SGVKTLFNPAP------------AIADLDPQFYTLSDVFCCNESEAEILTG 208
+ +R K F P + D + +D+ N +E LTG
Sbjct: 93 TINRVKRIKDNKKVYFLCDPILGDNGKMYTKSEVQDSMKELIKYADIITPNATELSFLTG 152
Query: 209 LTVGSAADAGEAALVLLKRGCQVVIITLGAEG------CVVLSQTEPEPKHIPTEKVKAV 262
L V S ++A +A +L ++G V+++T EG C + I +++
Sbjct: 153 LEVNSVSEAIKACHILHEQGIPVILVTSIKEGNDIILLCSFKDTLNNKNFTIKIPRIEG- 211
Query: 263 DTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFI 297
D TG GD+ + LE +NR+
Sbjct: 212 DFTGVGDTL--TYILLSWIIKGIPLEHAVNRAIST 244
>1YGJ-A nrPDB
Length = 312
Score = 55.5 bits (132), Expect = 3e-08, Method: Composition-based stats.
Identities = 37/181 (20%), Positives = 66/181 (36%), Gaps = 33/181 (18%)
Query: 168 RRSGVKTLFNPAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKR 227
+R+G ++ P + + ++D+ N+ EAE+LTG + S +A E +L
Sbjct: 119 QRNGEGAMYVPDDLLPVYREKVVPVADIITPNQFEAELLTGRKIHSQEEALEVMDMLHSM 178
Query: 228 GCQVVII---------------------TLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTG 266
G V+I T +G VV + E + V G
Sbjct: 179 GPDTVVITSSNLLSPRGSDYLMALGSQRTRAPDGSVVTQRIRMEMHKVDAVFV------G 232
Query: 267 AGDSFVGALAFYLAYYPNLS---LEDMLNRSNFIAAVSVQAAGTQSS---YPYKKDLPLT 320
GD F L + +PN E ++ + + +++ A +S P L L
Sbjct: 233 TGDLFAAMLLAWTHKHPNNLKVACEKTVSAMHHVLQRTIKCAKAKSGEGVKPSPAQLELR 292
Query: 321 L 321
+
Sbjct: 293 M 293
>2F7K-A nrPDB
Length = 327
Score = 53.6 bits (127), Expect = 1e-07, Method: Composition-based stats.
Identities = 37/173 (21%), Positives = 65/173 (37%), Gaps = 21/173 (12%)
Query: 170 SGVKTLFNPAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGC 229
G +++ P + + L+D+ N+ EAE+L+G + S +A +L G
Sbjct: 136 DGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGP 195
Query: 230 QVVIITL----GAEGCVVLSQTEPEPKHIPTEKV---------KAVDT--TGAGDSFVGA 274
V+IT +G L + + P V + VD G GD F
Sbjct: 196 DTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAM 255
Query: 275 LAFYLAYYPNLS---LEDMLNRSNFIAAVSVQAAGTQSS---YPYKKDLPLTL 321
L + +PN E ++ + + ++Q A Q+ P L L +
Sbjct: 256 LLAWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQAGEGVRPSPMQLELRM 308
>2I5B-A nrPDB
Length = 271
Score = 53.6 bits (127), Expect = 1e-07, Method: Composition-based stats.
Identities = 31/124 (25%), Positives = 50/124 (40%), Gaps = 11/124 (8%)
Query: 178 PAPAIADLDPQFYTLSDVFCCNESEAEILTGL-TVGSAADAGEAALVLLKRGCQVVIITL 236
L Q L+ V N EA L+G+ + + D EAA + G Q V+IT
Sbjct: 120 YPEHAQALREQLAPLATVITPNLFEASQLSGMDELKTVDDMIEAAKKIHALGAQYVVITG 179
Query: 237 GAEGCVVLSQTEPEPKHIPTEKV---KAVD---TTGAGDSFVGALAFYLAYYPNLSLEDM 290
G G + + T +V + +D T GAG +F A+ LA +++
Sbjct: 180 G--GKLKHEKAVDVLYDGETAEVLESEMIDTPYTHGAGCTFSAAVTAELA--KGAEVKEA 235
Query: 291 LNRS 294
+ +
Sbjct: 236 IYAA 239
>4JJP-A nrPDB
Length = 267
Score = 53.2 bits (126), Expect = 2e-07, Method: Composition-based stats.
Identities = 41/236 (17%), Positives = 82/236 (34%), Gaps = 31/236 (13%)
Query: 76 GKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASII-VNNEGQNIIVIVAGANLLLNTE 134
G DS G I + + G + I + + + V N + +
Sbjct: 16 GSDSSG--------GAGIQADLKTFSAIGTYGMSVITAITAQNTKGVFAVEDLNKKIIKK 67
Query: 135 DLRAAANVI--SRAKVMVCQLEITPATSLEALTMARR-SGVKTLFNP------------A 179
+ A I K+ + +P LE + ++ + + +P
Sbjct: 68 QIEAVFEDIPPRAVKIGMVS---SPEIILEIVENLKKYNPKYLVVDPVMISKSGYYLLKP 124
Query: 180 PAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGA- 238
A +L L+ + N EAE +TG+ + + D +L+ G + V++ G
Sbjct: 125 EAKENLIKYLIPLAYIITPNIPEAEEITGIKIHNVDDMKRVGEEILQLGPKFVLMKGGHL 184
Query: 239 EGCVVLSQTEPEPKHIP-TEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNR 293
+G V + +E++ +T G G + A+ YLA + + +N
Sbjct: 185 DGEAVDILVGKNIFKVYKSERIDKKNTHGTGCTLSSAITSYLAL--GYEITEAVNL 238
>1TD2-A nrPDB
Length = 287
Score = 46.3 bits (108), Expect = 2e-05, Method: Composition-based stats.
Identities = 34/131 (25%), Positives = 48/131 (36%), Gaps = 15/131 (11%)
Query: 190 YTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCV------V 243
SD+ N E EIL V + +A AA L+ +G Q+V++ A +
Sbjct: 137 LPASDIIAPNLVELEILCEHAVNNVEEAVLAARELIAQGPQIVLVKHLARAGYSRDRFEM 196
Query: 244 LSQTEPEPKHIPTEKVK--AVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAA-- 299
L T E HI V G GD G L L +L++ L + AA
Sbjct: 197 LLVTADEAWHISRPLVDFGMRQPVGVGDVTSGLLLVKL--LQGATLQEALE--HVTAAVY 252
Query: 300 -VSVQAAGTQS 309
+ V Q
Sbjct: 253 EIMVTTKAMQE 263
>2DDM-A nrPDB
Length = 283
Score = 46.3 bits (108), Expect = 2e-05, Method: Composition-based stats.
Identities = 28/117 (23%), Positives = 40/117 (34%), Gaps = 12/117 (10%)
Query: 185 LDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVL 244
L+ N E EILTG A AA LL + V++T A G
Sbjct: 145 YRQYLLPLAQGITPNIFELEILTGKNCRDLDSAIAAAKSLLSDTLKWVVVT-SASGN--E 201
Query: 245 SQTEPEPKHIPTEKVKAV-------DTTGAGDSFVGALAFYLAYYPNLSLEDMLNRS 294
E + + + V + D G GD F L +L D ++R+
Sbjct: 202 ENQEMQVVVVTADSVNVISHSRVKTDLKGTGDLFCAQL--ISGLLKGKALTDAVHRA 256
>3PZS-A nrPDB
Length = 289
Score = 45.1 bits (105), Expect = 4e-05, Method: Composition-based stats.
Identities = 27/122 (22%), Positives = 43/122 (35%), Gaps = 12/122 (9%)
Query: 187 PQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIIT-LGAEG----- 240
+ SD+ N E E L+G V + A + A L RG +VV++ L G
Sbjct: 136 NEALPASDMIAPNLLELEQLSGERVENVEQAVQVARSLCARGPKVVLVKHLSRAGYHADC 195
Query: 241 --CVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIA 298
++++ + P G GD G + L+ L + A
Sbjct: 196 FEMLLVTADDAWHICRPLVDFGKRQPVGVGDLTSG--LLLVNLLKGEPLDKALE--HVTA 251
Query: 299 AV 300
AV
Sbjct: 252 AV 253
>5TQI-A nrPDB
Length = 294
Score = 44.0 bits (102), Expect = 8e-05, Method: Composition-based stats.
Identities = 34/182 (18%), Positives = 62/182 (34%), Gaps = 37/182 (20%)
Query: 138 AAANVISRAKVMVCQLEITPATSLEALTMARRS---------------GVKTLFNPAPAI 182
AA + R ++ +PA + + + R G P P +
Sbjct: 75 AAIGALKRCDAVLSGFAGSPAQARATVEIVRAVKAMNPNAWYFCDPAMGQTGGIRPEPGV 134
Query: 183 AD-LDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITL----- 236
+ + + L+D N +E + L G + + A+A +A L+ RG +++++
Sbjct: 135 EEFIVNEMPALADGMSPNHTELQKLAGRRIETVAEAVDACRTLIARGPKIILVKHLHDRN 194
Query: 237 ---GAEGCVVLSQTE-----PEPKHIPTEKVKAVDTTGA--------GDSFVGALAFYLA 280
+ +++TE P V D T A GDS A LA
Sbjct: 195 SPADRFNMLAVTETEAWIGQRPLYAFPRHPVGVGDLTSAIFVARRLRGDSVRAAFEHTLA 254
Query: 281 YY 282
Sbjct: 255 AV 256
>5B6A-A nrPDB
Length = 288
Score = 43.6 bits (101), Expect = 1e-04, Method: Composition-based stats.
Identities = 27/159 (16%), Positives = 48/159 (30%), Gaps = 15/159 (9%)
Query: 149 MVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDPQFYTLSDVFCCNESEAEILTG 208
+V +++ +L K L + ++D C N+ E +
Sbjct: 98 VVARIKQANPRALYLCDPVMGHPEKGCIVAPEVSDFLLEEAAAVADYLCPNQLELDSFCD 157
Query: 209 LTVGSAADAGEAALVLLKRGCQVVIITL----GAEG------CVVLSQTEPEPKHIPTEK 258
S AD E A LL RG + +++ G G V Q + +
Sbjct: 158 RQPNSLADCVEMARSLLARGPRAILVKHLNYPGKAGDTFEMLLVAADQAWHLQRPLLAFP 217
Query: 259 VKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFI 297
+ V G GD + + F L + +
Sbjct: 218 RQPV---GVGD--LASGLFLSRLLLGDDLRNAFEFTGAA 251
>1UB0-A nrPDB
Length = 258
Score = 42.8 bits (99), Expect = 2e-04, Method: Composition-based stats.
Identities = 27/111 (24%), Positives = 43/111 (38%), Gaps = 5/111 (4%)
Query: 189 FYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLG---AEGCVVLS 245
+ L+D+ N EAE L G + + +A EAA LL G + V++ G E V L
Sbjct: 127 LFPLADLVTPNRLEAEALLGRPIRTLKEAEEAAKALLALGPKAVLLKGGHLEGEEAVDLL 186
Query: 246 QTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNF 296
T +V +T G G + + A L + + +
Sbjct: 187 ATRGGVLRFSAPRVHTRNTHGTGCT--LSAAIAALLAKGRPLAEAVAEAKA 235
>3ZS7-A nrPDB
Length = 300
Score = 42.1 bits (97), Expect = 4e-04, Method: Composition-based stats.
Identities = 18/65 (27%), Positives = 27/65 (41%)
Query: 171 GVKTLFNPAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQ 230
G + + D + L+D+ N EA +L+G+TV + A AA G
Sbjct: 121 GDDGIMYCKKEVLDAYRELVPLADIVTPNYFEASLLSGVTVNDLSSAILAADWFHNCGVA 180
Query: 231 VVIIT 235
VII
Sbjct: 181 HVIIK 185
>3MBJ-A nrPDB
Length = 291
Score = 37.8 bits (86), Expect = 0.006, Method: Composition-based stats.
Identities = 25/135 (18%), Positives = 44/135 (32%), Gaps = 14/135 (10%)
Query: 170 SGVKTLFNPAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVG---SAADAGEAALVLLK 226
+G + ++ T +DV N +E L + + E +L
Sbjct: 118 NGRLYTNFDMEMVKEMRH-LITKADVITPNLTELFYLLDEPYKADSTDEELKEYLRLLSD 176
Query: 227 RGCQVVIITLGA-------EGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYL 279
+G QVVIIT ++ + + A G GD+F +
Sbjct: 177 KGPQVVIITSVPVHDEPHKTSVYAYNRQGNRYWKVTCPYLPAHYP-GTGDTFTSVITG-- 233
Query: 280 AYYPNLSLEDMLNRS 294
+ SL L+R+
Sbjct: 234 SLMQGDSLPMALDRA 248
>4XF7-A nrPDB
Length = 273
Score = 37.4 bits (85), Expect = 0.008, Method: Composition-based stats.
Identities = 44/290 (15%), Positives = 84/290 (28%), Gaps = 50/290 (17%)
Query: 17 AVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVG 76
+VVG + D+V G+K GG + +R ++
Sbjct: 2 KCLVVGHVVRDIVKK------------GNKVLERLGGGAYYSALALSRF-CDVEILT--- 45
Query: 77 KDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDL 136
SF N E +K+ + + + T ++ + + ++ + + +
Sbjct: 46 --SFSNLPEEWIKELESMAKLQVVPSETTTTYELTYLDGNRRRLKLLERASPIEELPD-- 101
Query: 137 RAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKT---LFNPAPAIADLDPQ---FY 190
+ E+ PA AL V + + +P P F
Sbjct: 102 ----GEYDVLLMNPVAREVPPALVTSALKKFPFVAVDIQGFIRSSSPGEIQYQPIDGSFL 157
Query: 191 TLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPE 250
+ + E + L G + V++++ G E
Sbjct: 158 KGVKILHADLGEYQYLQGFSPEF---------------VDVLLLSNGPEPGKAFLHGREY 202
Query: 251 PKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAV 300
V +TGAGD F+GA +Y L R+ A+
Sbjct: 203 TFEPVHVGVDE--STGAGDVFLGAFT---GFYSQCPFVQALKRAAAFTAL 247
>3HYO-A nrPDB
Length = 282
Score = 36.3 bits (82), Expect = 0.017, Method: Composition-based stats.
Identities = 32/142 (22%), Positives = 49/142 (34%), Gaps = 18/142 (12%)
Query: 188 QFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVL---LKRGCQVVI--ITLGAE-GC 241
Q +DV N +EA +LTG D L LK G VI + + GC
Sbjct: 130 QLIQQADVILPNTTEAALLTGAPYQVTPDLEVILPALQAQLKTGAHAVITDVQRADQIGC 189
Query: 242 VVLSQTEP----EPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFI 297
L + + +P G GD+ +A L L L R+N
Sbjct: 190 AWLDEAGHVQYCGARRLPGHY------NGTGDTLAAVIAGLLGR--GYPLAPTLARANQW 241
Query: 298 AAVSVQAAGTQSSYPYKKDLPL 319
++V Q+ ++ + L
Sbjct: 242 LNMAVAETIAQNRTDDRQGVAL 263
>4YL5-A nrPDB
Length = 263
Score = 35.9 bits (81), Expect = 0.027, Method: Composition-based stats.
Identities = 14/60 (23%), Positives = 24/60 (40%), Gaps = 5/60 (8%)
Query: 188 QFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQT 247
+ L+ + N E LTG+T D +A L + G + V++ G E +
Sbjct: 135 ELIPLATLITPNTVELRALTGVT-----DLDQATQKLFEMGAKAVLVKGGHEDTPDFIKN 189
>5MEK-A nrPDB
Length = 322
Score = 35.5 bits (80), Expect = 0.034, Method: Composition-based stats.
Identities = 18/101 (17%), Positives = 37/101 (36%), Gaps = 3/101 (2%)
Query: 146 AKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDPQFYTLSDVFCCNESEAEI 205
+ +VC T T L+ALT A + + + P + +F ++ E ++
Sbjct: 59 SDFLVCSYPKTGTTWLKALTFAIANRSRFDDSSNPLLKRNPHEFVPYIEIDFPFFPEVDV 118
Query: 206 LT---GLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVV 243
L + ++K GC++V I + +
Sbjct: 119 LKDKGNTLFSTHIPYELLPDSVVKSGCKMVYIWREPKDTFI 159
>5ZWB-B nrPDB
Length = 296
Score = 35.1 bits (79), Expect = 0.044, Method: Composition-based stats.
Identities = 24/121 (19%), Positives = 36/121 (29%), Gaps = 7/121 (5%)
Query: 179 APAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGA 238
A + N E E+L+G + +A AA LL + V+IT
Sbjct: 144 AEIPQAYRTHLLPQAQGLTPNVFELEMLSGKPCRTLEEAVAAAQSLLSDTLKWVVITSAP 203
Query: 239 EGCV----VLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRS 294
+ V T + +V A + G GD F L L +
Sbjct: 204 GESLETITVAVVTAQVVEVFAHPRV-ATELKGTGDLFCAELV--SGIVQGKKLTTAAKDA 260
Query: 295 N 295
Sbjct: 261 A 261
>4I8O-A nrPDB
Length = 358
Score = 32.4 bits (72), Expect = 0.29, Method: Composition-based stats.
Identities = 12/55 (21%), Positives = 17/55 (30%)
Query: 94 STEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDLRAAANVISRAKV 148
+ T I N +G I + GAN L E I+ A+
Sbjct: 44 GLRVVFTRPGVNLATVDIFYNGDGSTTIQYLTGANRSLGQELADHLFETINPAEF 98
>3CGD-A nrPDB
Length = 480
Score = 32.1 bits (71), Expect = 0.38, Method: Composition-based stats.
Identities = 39/204 (19%), Positives = 66/204 (32%), Gaps = 26/204 (12%)
Query: 83 DYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDLRAAANV 142
Y E+ K D+ EF+Y ATG ++ EG+++ + LL D
Sbjct: 126 VYAEHTKTKDV-FEFSYDRLLIATGVRPVMPEWEGRDLQGVH----LLKTIPDAERILKT 180
Query: 143 ISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAI------ADLDPQFYTLSDVF 196
+ KV + A LE G K D+ Y +D
Sbjct: 181 LETNKVEDVTIIGGGAIGLEMAETFVELGKKVRMIERNDHIGTIYDGDMAEYIYKEAD-- 238
Query: 197 CCNESEAEILTGLTVGSAADAGEAALVLLKRG---CQVVIITLGAE-------GCVVLSQ 246
+ EILT V + V +G +V++++G + G + +
Sbjct: 239 ---KHHIEILTNENVKAFKGNERVEAVETDKGTYKADLVLVSVGVKPNTDFLEGTNIRTN 295
Query: 247 TEPEPKHIPTEKVKAVDTTGAGDS 270
+ + + D AGD
Sbjct: 296 HKGAIEVNAYMQTNVQDVYAAGDC 319
>6CY1-A nrPDB
Length = 329
Score = 30.1 bits (66), Expect = 1.2, Method: Composition-based stats.
Identities = 35/181 (19%), Positives = 65/181 (35%), Gaps = 6/181 (3%)
Query: 140 ANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDPQFYTLSDVFCCN 199
+ +SRA V +++ LE + +A GV+T I + + +V N
Sbjct: 37 FDKVSRAVVGKSKVDDEVLDDLEEVLIASDVGVETTVKIIRRIEERVAR-DKYVNVAELN 95
Query: 200 ESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPTEKV 259
E ++GL + + + K VI+ +G G + +E +
Sbjct: 96 NILREEISGLLLE---NPHAGTQNIDKTKKPYVIMVVGVNGVGKTTTIGKLAHQFKSEGL 152
Query: 260 KAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPYKKDLPL 319
K V GA D+F A L + ++ ++ SV QS+ D+ +
Sbjct: 153 KVV--LGAADTFRAAAVDQLVIWSERVGVPIVKQAMGSDPASVAFDTVQSAVSQDADVVI 210
Query: 320 T 320
Sbjct: 211 I 211
>1J08-A nrPDB
Length = 226
Score = 29.7 bits (65), Expect = 1.6, Method: Composition-based stats.
Identities = 18/111 (16%), Positives = 26/111 (23%), Gaps = 6/111 (5%)
Query: 165 TMARRSGVKTLFNPAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAG-----E 219
+ + + NP I + + D E LT D E
Sbjct: 10 RIIKEEFFSKMVNPVKLIVFIGKEHCQYCDQLKQLVQELSELTDKLSYEIVDFDTPEGKE 69
Query: 220 AALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDS 270
A IT + V P VD + GD+
Sbjct: 70 LAEKYRIDRAPATTITQDGKDFGVRYFGIPAGHEFAAFLEDIVDVS-KGDT 119
>1BJ4-A nrPDB
Length = 470
Score = 28.6 bits (62), Expect = 3.8, Method: Composition-based stats.
Identities = 18/132 (13%), Positives = 37/132 (28%), Gaps = 18/132 (13%)
Query: 49 IGFGGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGT 108
+ G AN V A + + G +L T K + T
Sbjct: 106 QPYSGSPANFAVYTALV------------EPHGRIMGLDLPDGGHLTHGFMTDKKKISAT 153
Query: 109 ASIIVNNEGQNIIVIVAGANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALT-MA 167
+ +++ V +N + L A + ++ + L +A
Sbjct: 154 SIFF-----ESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIA 208
Query: 168 RRSGVKTLFNPA 179
+G + + A
Sbjct: 209 DENGAYLMADMA 220
>1OXJ-A nrPDB
Length = 173
Score = 28.2 bits (61), Expect = 5.5, Method: Composition-based stats.
Identities = 18/94 (19%), Positives = 45/94 (47%), Gaps = 2/94 (2%)
Query: 106 TGTASIIVNNEGQNIIVIVAGANLLLN--TEDLRAAANVISRAKVMVCQLEITPATSLEA 163
T +++ + + + GA+ L + L+ AN+++R + + ++ +T++E
Sbjct: 30 TYEEMLLITEDFLQSVGVTKGASHKLALCIDKLKERANILNRVEQELLSGQMELSTAVEE 89
Query: 164 LTMARRSGVKTLFNPAPAIADLDPQFYTLSDVFC 197
LT + +K L +P P ++ +F + D+
Sbjct: 90 LTNIVLTPMKPLESPGPPEENIGLRFLKVIDIVT 123
>4EVZ-A nrPDB
Length = 258
Score = 27.4 bits (59), Expect = 9.5, Method: Composition-based stats.
Identities = 29/193 (15%), Positives = 62/193 (32%), Gaps = 11/193 (5%)
Query: 113 VNNEGQNIIVIVAGANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGV 172
+ EG + +V + E + + + + + +A + R
Sbjct: 39 YDEEGADELVFLDITASHEGRETMLEVVERTAEQVFIPLTVGGGIRSVEDASRLLRAGAD 98
Query: 173 KTLFNPA-----PAIADLDPQFYTLSDVFCCNESEA----EILT-GLTVGSAADAGEAAL 222
K N A I + +F + + V + E+ T G + DA E A
Sbjct: 99 KVSINTAAVKNPELITEAAEEFGSQAVVVAIDAKRVGGGWEVFTHGGRKPTGLDAVEWAR 158
Query: 223 VLLKRGC-QVVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAY 281
+++ G ++++ ++ +G E V + + GAG+ A F L
Sbjct: 159 KVVELGAGEILLTSMDRDGTKAGYDLELTRAVSEAVSVPVIASGGAGELEHFAEVFELEG 218
Query: 282 YPNLSLEDMLNRS 294
+ +
Sbjct: 219 ADAALAASIFHFG 231
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
Posted date: Jan 3, 2023 9:05 PM
Number of letters in database: 10,336,785
Number of sequences in database: 36,641
Lambda K H
0.306 0.125 0.304
Lambda K H
0.267 0.0389 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,895,886
Number of Sequences: 36641
Number of extensions: 343091
Number of successful extensions: 1548
Number of sequences better than 10.0: 84
Number of HSP's better than 10.0 without gapping: 108
Number of HSP's successfully gapped in prelim test: 38
Number of HSP's that attempted gapping in prelim test: 1188
Number of HSP's gapped (non-prelim): 161
length of query: 322
length of database: 10,336,785
effective HSP length: 97
effective length of query: 225
effective length of database: 6,782,608
effective search space: 1526086800
effective search space used: 1526086800
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.1 bits)
S2: 59 (27.4 bits)