BLASTP 2.2.23 [Feb-03-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.


Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= Q9H477
         (322 letters)

Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 
           36,641 sequences; 10,336,785 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

5C40-A nrPDB                                                          663   0.0  
5ZWY-A nrPDB                                                          217   4e-57
3RY7-A nrPDB                                                          180   1e-45
1RK2-A nrPDB                                                          163   1e-40
4X8F-A nrPDB                                                          157   4e-39
1VM7-A nrPDB                                                          134   7e-32
6ILS-A nrPDB                                                          120   1e-27
3I3Y-A nrPDB                                                           91   5e-19
6CW5-A nrPDB                                                           78   4e-15
3HJ6-A nrPDB                                                           74   6e-14
1TYY-A nrPDB                                                           71   7e-13
3GBU-A nrPDB                                                           66   2e-11
3GO6-A nrPDB                                                           65   5e-11
3KZH-A nrPDB                                                           64   7e-11
5EYN-A nrPDB                                                           64   7e-11
1V1S-A nrPDB                                                           63   2e-10
3UBO-A nrPDB                                                           62   4e-10
3H49-A nrPDB                                                           59   3e-09
4LC4-A nrPDB                                                           58   5e-09
2NWH-A nrPDB                                                           58   5e-09
2RBC-A nrPDB                                                           58   5e-09
4WJM-A nrPDB                                                           54   8e-08
2QCV-A nrPDB                                                           53   2e-07
2QHP-A nrPDB                                                           53   2e-07
3IQ0-A nrPDB                                                           51   5e-07
2I6B-A nrPDB                                                           50   9e-07
3PL2-A nrPDB                                                           48   6e-06
3LJS-A nrPDB                                                           48   7e-06
2C4E-A nrPDB                                                           47   7e-06
3N1C-A nrPDB                                                           47   1e-05
4DU5-A nrPDB                                                           46   2e-05
3LHX-A nrPDB                                                           46   2e-05
1WYE-A nrPDB                                                           46   2e-05
3LOO-A nrPDB                                                           45   5e-05
2JG5-A nrPDB                                                           44   1e-04
4N08-A nrPDB                                                           42   4e-04
5KB6-A nrPDB                                                           42   4e-04
2HW1-A nrPDB                                                           40   0.001
3UQ9-A nrPDB                                                           39   0.002
3KD6-A nrPDB                                                           39   0.003
2VAR-A nrPDB                                                           39   0.003
3NCA-A nrPDB                                                           39   0.003
3B1N-A nrPDB                                                           37   0.008
1YGJ-A nrPDB                                                           37   0.012
2F7K-A nrPDB                                                           36   0.029
3BF5-A nrPDB                                                           33   0.14 
2AFB-A nrPDB                                                           33   0.23 
2AWD-A nrPDB                                                           32   0.45 
1HKH-A nrPDB                                                           30   1.8  
4GM6-A nrPDB                                                           29   2.3  
2AA0-A nrPDB                                                           29   3.5  
3LUF-A nrPDB                                                           28   4.9  
3JUL-A nrPDB                                                           28   6.6  
1OXJ-A nrPDB                                                           28   7.2  

>5C40-A nrPDB
          Length = 330

 Score =  663 bits (1710), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 322/322 (100%), Positives = 322/322 (100%)

Query: 1   MAASGEPQRQWQEEVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCV 60
           MAASGEPQRQWQEEVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCV
Sbjct: 1   MAASGEPQRQWQEEVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCV 60

Query: 61  QAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNI 120
           QAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNI
Sbjct: 61  QAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNI 120

Query: 121 IVIVAGANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAP 180
           IVIVAGANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAP
Sbjct: 121 IVIVAGANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAP 180

Query: 181 AIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEG 240
           AIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEG
Sbjct: 181 AIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEG 240

Query: 241 CVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAV 300
           CVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAV
Sbjct: 241 CVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAV 300

Query: 301 SVQAAGTQSSYPYKKDLPLTLF 322
           SVQAAGTQSSYPYKKDLPLTLF
Sbjct: 301 SVQAAGTQSSYPYKKDLPLTLF 322


>5ZWY-A nrPDB
          Length = 349

 Score =  217 bits (553), Expect = 4e-57,   Method: Compositional matrix adjust.
 Identities = 132/317 (41%), Positives = 180/317 (56%), Gaps = 15/317 (4%)

Query: 13  EEVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMV 72
           E    ++VVGSC  D V     +P+ GET+H   F  GFGGKGANQ V A RLGA  +MV
Sbjct: 33  EYAPDILVVGSCFLDYVGYVDHMPQVGETMHSVSFHKGFGGKGANQAVAAGRLGAKVAMV 92

Query: 73  CKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNE-GQNIIVIVAGANLLL 131
             VG D  G+DYI+ L++N + T + ++T  ++TG A I+V+ +   N IVI   A    
Sbjct: 93  SMVGTDGDGSDYIKELERNGVDTAYMFRTGKSSTGLAMILVDTKSSNNEIVICPNATNHF 152

Query: 132 NTEDLRAAANVISRA-----KVMVCQLEITPATSLEALTMARRSGVKTLFNPAPA----- 181
             E LRA  N   R      K ++CQ EI   T+L+ +  A   GV T+FN APA     
Sbjct: 153 TPELLRAQTNNYERILHTGLKYLICQNEIPLPTTLDTIKEAHSRGVYTVFNSAPAPKPAE 212

Query: 182 IADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGC 241
           +  + P F     +FC NE EA ++TG+ V     A  A   L + G + V+ITLGA G 
Sbjct: 213 VEQIKP-FLPYVSLFCPNEVEATLITGVKVTDTESAFSAIKALQQLGVRDVVITLGAAG- 270

Query: 242 VVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVS 301
            VLS+   EP H+  + VKAVDTTGAGD FVG++ ++++   NL   +   R+N  AA+S
Sbjct: 271 FVLSENGAEPVHVTGKHVKAVDTTGAGDCFVGSMVYFMSRGRNLL--EACKRANECAAIS 328

Query: 302 VQAAGTQSSYPYKKDLP 318
           V   GTQ SYP+  +LP
Sbjct: 329 VTRKGTQLSYPHPSELP 345


>3RY7-A nrPDB
          Length = 304

 Score =  180 bits (456), Expect = 1e-45,   Method: Compositional matrix adjust.
 Identities = 110/296 (37%), Positives = 164/296 (55%), Gaps = 5/296 (1%)

Query: 18  VVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGG-KGANQCVQAARLGAMTSMVCKVG 76
           VV++GS   D      R  + GET+H  +    FGG KGANQ +  AR+ A T+ + K+G
Sbjct: 5   VVILGSTNVDQFLTVERYAQPGETLHVEEAQKAFGGGKGANQAIATARMQADTTFITKIG 64

Query: 77  KDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDL 136
            D   +  +E+ K   I T +  +T +A TG A I VN EGQN I +  GAN+ +  ED+
Sbjct: 65  TDGVADFILEDFKVAHIDTSYIIKTAEAKTGQAFITVNAEGQNTIYVYGGANMTMTPEDV 124

Query: 137 RAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDPQFYTLSDVF 196
             A + I  A  +V QLE+     + A  +A+  GV T+ NPAPA A L  +  +L D+ 
Sbjct: 125 INAKDAIINADFVVAQLEVPIPAIISAFEIAKAHGVTTVLNPAPAKA-LPNELLSLIDII 183

Query: 197 CCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPT 256
             NE+EAE+L+G+ V +     + A   L  G + V+ITLG +G      T+ + +HI  
Sbjct: 184 VPNETEAELLSGIKVTNEQSMKDNANYFLSIGIKTVLITLGKQGTYF--ATKNQSQHIEA 241

Query: 257 EKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYP 312
            KV A+DTT AGD+F+GA    L    + +L D ++  N  ++++VQ  G Q+S P
Sbjct: 242 YKVNAIDTTAAGDTFIGAFVSRLNKSQD-NLADAIDFGNKASSLTVQKHGAQASIP 296


>1RK2-A nrPDB
          Length = 309

 Score =  163 bits (412), Expect = 1e-40,   Method: Compositional matrix adjust.
 Identities = 108/305 (35%), Positives = 164/305 (53%), Gaps = 5/305 (1%)

Query: 13  EEVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMV 72
           +   ++VV+GS   D +      P  GET+ G+ + + FGGKGANQ V A R GA  + +
Sbjct: 2   QNAGSLVVLGSINADHILNLQSFPTPGETVTGNHYQVAFGGKGANQAVAAGRSGANIAFI 61

Query: 73  CKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLN 132
              G DS G    + L  ++I        K  +TG A I VN EG+N+I I AGAN  L+
Sbjct: 62  ACTGDDSIGESVRQQLATDNIDITPVSVIKGESTGVALIFVNGEGENVIGIHAGANAALS 121

Query: 133 TEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDPQFYTL 192
              + A    I+ A  ++ QLE    + + A  +A ++      NPAPA  +L  +   L
Sbjct: 122 PALVEAQRERIANASALLMQLESPLESVMAAAKIAHQNKTIVALNPAPA-RELPDELLAL 180

Query: 193 SDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPK 252
            D+   NE+EAE LTG+ V +  DA +AA VL ++G + V+ITLG+ G  V +    E +
Sbjct: 181 VDIITPNETEAEKLTGIRVENDEDAAKAAQVLHEKGIRTVLITLGSRG--VWASVNGEGQ 238

Query: 253 HIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYP 312
            +P  +V+AVDT  AGD+F GAL    A      L + +  ++  AA++V   G Q S P
Sbjct: 239 RVPGFRVQAVDTIAAGDTFNGAL--ITALLEEKPLPEAIRFAHAAAAIAVTRKGAQPSVP 296

Query: 313 YKKDL 317
           +++++
Sbjct: 297 WREEI 301


>4X8F-A nrPDB
          Length = 309

 Score =  157 bits (398), Expect = 4e-39,   Method: Compositional matrix adjust.
 Identities = 114/300 (38%), Positives = 162/300 (54%), Gaps = 5/300 (1%)

Query: 18  VVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGK 77
           +VV+GS   D V      P+ GET+HG  + +  GGKGANQ V AAR+ A    +  VG 
Sbjct: 7   LVVLGSVNADHVLQVPSFPRPGETLHGRNYQVIPGGKGANQAVAAARMQADVGFIACVGD 66

Query: 78  DSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDLR 137
           DSFG +  E+ K + I+T       +  TG A I V++ G+N I I A AN  L    + 
Sbjct: 67  DSFGINIRESFKLDGINTAGVKLQPNCPTGIAMIQVSDSGENSICISAEANAKLTAAAIE 126

Query: 138 AAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDPQFYTLSDVFC 197
                I  A+ ++ QLE      L+A   A+ +    + NPAPA  +L  +     D+  
Sbjct: 127 PDLAAIRDARYLLMQLETPLDGILKAAQEAKTAKTNVILNPAPA-RELPDELLKCVDLIT 185

Query: 198 CNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPTE 257
            NE+EAE+LTG+TV   + A +AA  L  +G ++VIITLG++G V LSQ     + IP  
Sbjct: 186 PNETEAEVLTGITVYDDSSAQQAADALHCKGIEIVIITLGSKG-VWLSQNG-RGQRIPGF 243

Query: 258 KVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPYKKDL 317
            VKA DTT AGD+F GAL   L     + LE  +  ++  AA+SV   G Q+S P + ++
Sbjct: 244 VVKATDTTAAGDTFNGALVTGL--LQEMPLESAIKFAHAAAAISVTRFGAQTSIPTRAEV 301


>1VM7-A nrPDB
          Length = 311

 Score =  134 bits (336), Expect = 7e-32,   Method: Compositional matrix adjust.
 Identities = 106/301 (35%), Positives = 153/301 (50%), Gaps = 14/301 (4%)

Query: 18  VVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAM-TSMVCKVG 76
           + VVGS   D+V       K GET    +  +  GGKGANQ V  A++G      V  +G
Sbjct: 17  ISVVGSSNIDIVLKVDHFTKPGETQKAIEMNVFPGGKGANQAVTVAKIGEKGCRFVTCIG 76

Query: 77  KDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDL 136
            D + +  IEN ++  I+    Y      TG A I V+  GQN I+I  GAN  L  E +
Sbjct: 77  NDDYSDLLIENYEKLGITG---YIRVSLPTGRAFIEVDKTGQNRIIIFPGANAELKKELI 133

Query: 137 RAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDPQFYTLSDVF 196
               N +S + +++ Q EI   T+LE    A+R     +F+PAPA   ++ + +   D  
Sbjct: 134 DW--NTLSESDILLLQNEIPFETTLEC---AKRFNGIVIFDPAPA-QGINEEIFQYLDYL 187

Query: 197 CCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPT 256
             NE E E L+    G      +AA   L+ G + VI+ LG +G +++++ E   KH PT
Sbjct: 188 TPNEKEIEALSKDFFGEFLTVEKAAEKFLELGVKNVIVKLGDKGVLLVNKNEK--KHFPT 245

Query: 257 EKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPYKKD 316
            KVKAVDTT AGD F GA A  L+   N   E+ +      AA+SV   G QSS P +++
Sbjct: 246 FKVKAVDTTAAGDVFNGAFAVALSEGKN--PEEAVIFGTAAAAISVTRLGAQSSIPAREE 303

Query: 317 L 317
           +
Sbjct: 304 V 304


>6ILS-A nrPDB
          Length = 313

 Score =  120 bits (300), Expect = 1e-27,   Method: Compositional matrix adjust.
 Identities = 89/307 (28%), Positives = 146/307 (47%), Gaps = 13/307 (4%)

Query: 18  VVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGK 77
           +VVVGS   D+     RLPK GETI         GGKGANQ    A+L   T  V ++G+
Sbjct: 5   LVVVGSANADIYVEIERLPKEGETISAKTGQTLAGGKGANQAACGAKLMYPTYFVGRLGE 64

Query: 78  DSFGNDYIENLKQNDISTEFTY--QTKDAATGTASIIVNNEGQNIIVIVAGANL-----L 130
           D+ G    E L  +       Y     +  TG A +++ ++GQN I+IV GAN+     +
Sbjct: 65  DAHGKLIAEALGDDGCGVHLDYVRSVNNEPTGHAVVMLQSDGQNSIIIVGGANMKAWPEI 124

Query: 131 LNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDPQFY 190
           ++ +DL     ++  A +++ Q EI  + +++     +++GV  + +       +  +  
Sbjct: 125 MSDDDLE----IVRNAGIVLLQREIPDSINIQVAKAVKKAGVPVILDVGGMDTPIPNELL 180

Query: 191 TLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPE 250
              D+   NE+E   LTG+   +     +A     K G + V++ LG++G  +  Q E  
Sbjct: 181 DSIDILSPNETELSRLTGMPTETFEQISQAVAKCHKLGVKQVLVKLGSKGSALFIQGEKP 240

Query: 251 PKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSS 310
            +       + VDTTGAGD+F    AF +A     S E+ L  +   A++ VQ  G   S
Sbjct: 241 IQQSIIPAAQVVDTTGAGDTFTA--AFAVAMVEGKSHEECLRFAAAAASLCVQVKGAIPS 298

Query: 311 YPYKKDL 317
            P +K +
Sbjct: 299 MPDRKSV 305


>3I3Y-A nrPDB
          Length = 299

 Score = 91.3 bits (225), Expect = 5e-19,   Method: Compositional matrix adjust.
 Identities = 84/307 (27%), Positives = 138/307 (44%), Gaps = 36/307 (11%)

Query: 18  VVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGK 77
           V V G+   D       +PK G +IHG K     GGKGANQ +  +R G  T ++   G 
Sbjct: 5   VYVTGNITVDETWSIPDIPKKGASIHGVKVSQDIGGKGANQAIILSRCGIETRLIAATGN 64

Query: 78  DSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQN-IIVIVAGANLLLNTEDL 136
           DS G  +I    +N+          +  + T+ I+ + +G N II   A A+     E +
Sbjct: 65  DSNGA-WIRQQIKNEPLMLLPDGHFNQHSDTSIILNSADGDNAIITTTAAADTFSLDEMI 123

Query: 137 RAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDPQF---YTLS 193
              A+ ++   +++ Q   +   +      AR  G+ T+FNP+P    ++P F   + L 
Sbjct: 124 PHMADAVA-GDILLQQGNFSLDKTRALFQYARSRGMTTVFNPSP----VNPDFCHLWPLI 178

Query: 194 DVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKH 253
           D+   NESEAE+L                     G + ++IT GA G  ++   E + + 
Sbjct: 179 DIAVVNESEAELLQ------------------PYGVKTLVITQGAAGAWLVQ--EGQRQF 218

Query: 254 IPTEKVKAVDTTGAGDSFVGAL---AFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSS 310
            P    +A+DTTGAGD+F+  +   A      P+       +R+  I   +V   GT S+
Sbjct: 219 CPAVPAEALDTTGAGDTFLAVMLASALLRGVAPDALALAHASRAAAI---TVSRRGTLSA 275

Query: 311 YPYKKDL 317
           +P  ++L
Sbjct: 276 FPGSREL 282


>6CW5-A nrPDB
          Length = 332

 Score = 78.2 bits (191), Expect = 4e-15,   Method: Compositional matrix adjust.
 Identities = 91/316 (28%), Positives = 133/316 (42%), Gaps = 31/316 (9%)

Query: 19  VVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGKD 78
           +V GS   D       + + GETI         GGKGANQ    AR G    +   +G D
Sbjct: 16  LVRGSVNIDEFFHLPHIVRPGETISSTGLTKRAGGKGANQAFAVARAGGQVELDGAIGDD 75

Query: 79  SFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDLRA 138
             G    E L+   + T+     KD  TG A I    +G+N IV+ AGAN  L +     
Sbjct: 76  --GIWVKEMLESAGVGTDKLKIVKDEVTGRAVIQSAADGENSIVLHAGANYYLPSPTPTT 133

Query: 139 AANVISRAKVMVCQLEITPATSLEALTMARRSG--VKTLFNPAPAI--ADLDPQFYTLSD 194
           +    +    ++ Q E+  +++L  LT A +S   + ++FNP+P +  A L    +    
Sbjct: 134 SLATYTH---LLVQNEVPLSSTLAYLTAAGQSSPPLTSVFNPSPMLTPAQLREFPWKHLS 190

Query: 195 VFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQV----------------VIITLGA 238
               NE E   L  L  GS+A+ GEA    L+                     +I TLGA
Sbjct: 191 WLIVNEGELGDLL-LAFGSSANPGEAKEDELQAKASAGILELHENDYFSKNVGIICTLGA 249

Query: 239 EGCVVLSQTEPEPKHIPTEKVK--AVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNF 296
           +G ++  +   E  ++P  K++    DTTGAGD F G   F        SL+D L     
Sbjct: 250 KG-ILCYEPGKEVGYLPAAKLQNPVKDTTGAGDCFAG--YFVAGLMSGKSLQDALKTCLV 306

Query: 297 IAAVSVQAAGTQSSYP 312
              + V+  G   S P
Sbjct: 307 ACGICVENEGAMESVP 322


>3HJ6-A nrPDB
          Length = 327

 Score = 74.3 bits (181), Expect = 6e-14,   Method: Compositional matrix adjust.
 Identities = 82/315 (26%), Positives = 137/315 (43%), Gaps = 32/315 (10%)

Query: 18  VVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGK 77
           VV +G  + D++S      +        ++   FGG  AN  V  +RLG   +++ ++G 
Sbjct: 24  VVSLGEILVDMISTE----EVNSLSQSREYTRHFGGSPANIAVNLSRLGKKVALISRLGA 79

Query: 78  DSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDLR 137
           D+FGN  ++ LK   I T+   Q K+  T    +  +    + +     A++ L  +D+ 
Sbjct: 80  DAFGNYLLDVLKGEQIITDGIQQDKERRTTIVYVSKSTRTPDWLPYRE-ADMYLQEDDI- 137

Query: 138 AAANVISRAKVMVCQ---LEITPA--TSLEALTMARRSGVKTLFNP------APAIAD-- 184
               +I R+KV       L   PA  T+++A   AR  G    F+P       P   D  
Sbjct: 138 -IFELIKRSKVFHLSTFILSRKPARDTAIKAFNYAREQGKIVCFDPCYRKVLWPEGDDGA 196

Query: 185 -LDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAAL-VLLKRGCQVVIITLGAEGCV 242
            +  +  + +D    +  +A  L G       D+ E  +   L+ G + VI+TLG EG  
Sbjct: 197 GVVEEIISRADFVKPSLDDARHLFG------PDSPENYVKRYLELGVKAVILTLGEEG-- 248

Query: 243 VLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSV 302
           V++    E   IP     AVD TGAGD+F     F        +++  +   N +AA  +
Sbjct: 249 VIASDGEEIIRIPAFSEDAVDVTGAGDAFWS--GFICGLLDGYTVKRSIKLGNGVAAFKI 306

Query: 303 QAAGTQSSYPYKKDL 317
           +  G  S  P K+D+
Sbjct: 307 RGVGALSPVPSKEDI 321


>1TYY-A nrPDB
          Length = 339

 Score = 70.9 bits (172), Expect = 7e-13,   Method: Compositional matrix adjust.
 Identities = 78/282 (27%), Positives = 119/282 (42%), Gaps = 24/282 (8%)

Query: 52  GGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASI 111
           GG  AN  V  ARLG     +  +G D  G  ++  + Q D   + T+   DA   +A +
Sbjct: 50  GGASANVGVCVARLGGECGFIGCLGDDDAGR-FLRQVFQ-DNGVDVTFLRLDADLTSAVL 107

Query: 112 IVN----NEGQNIIVIVAGANLLLNTEDLRAAANVISRAKVMVCQLEITPATS--LEALT 165
           IVN     E     ++  GA+  ++ +DL                L   PA    LE   
Sbjct: 108 IVNLTADGERSFTYLVHPGADTYVSPQDL-PPFRQYEWFYFSSIGLTDRPAREACLEGAR 166

Query: 166 MARRSGVKTLFN-----PAPAIADLDPQFYTLSDVFC--CNESEAEILTGLTVGSAADAG 218
             R +G   LF+           D  P+    S      C  S  E+     +  A+   
Sbjct: 167 RMREAGGYVLFDVNLRSKMWGNTDEIPELIARSAALASICKVSADELCQ---LSGASHWQ 223

Query: 219 EAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFY 278
           +A   L   GC   II+LGA+G +++  T     H P  +V  VDTTGAGD+FVG L F 
Sbjct: 224 DARYYLRDLGCDTTIISLGADGALLI--TAEGEFHFPAPRVDVVDTTGAGDAFVGGLLFT 281

Query: 279 LAY---YPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPYKKDL 317
           L+    + +  L + ++ +N   A++V A G  ++ P+   L
Sbjct: 282 LSRANCWDHALLAEAISNANACGAMAVTAKGAMTALPFPDQL 323


>3GBU-A nrPDB
          Length = 313

 Score = 65.9 bits (159), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 75/310 (24%), Positives = 135/310 (43%), Gaps = 35/310 (11%)

Query: 21  VGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGKDSF 80
           +G  + DL+S+     K       H      GG  AN  V  +RLG  +S++ KVG D F
Sbjct: 7   IGELLIDLISVEEGDLKDVRLFEKHP-----GGAPANVAVGVSRLGVKSSLISKVGNDPF 61

Query: 81  GNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVI--VAGANLLLNTEDLRA 138
           G   IE L + ++ T    + +   TG   + +     + ++   VA  N+ LN  +   
Sbjct: 62  GEYLIEELSKENVDTRGIVKDEKKHTGIVFVQLKGASPSFLLYDDVAYFNMTLNDINW-- 119

Query: 139 AANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDPQFYTLS---DV 195
             +++  AK++          +  ++ +AR    +T+      I       + ++   D+
Sbjct: 120 --DIVEEAKIV----------NFGSVILARNPSRETVMKVIKKIKGSSLIAFDVNLRLDL 167

Query: 196 FCCNESEA-EIL-TGLTVGSAADAGEAALVLLK------RGCQVVIITLGAEGCVVLSQT 247
           +   E E  ++L   + +     A E  ++ L+      +G  +  ITLG +G  ++   
Sbjct: 168 WRGQEEEMIKVLEESIKLADIVKASEEEVLYLENQGVEVKGSMLTAITLGPKGFRLIKNE 227

Query: 248 EPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGT 307
                 +P+  V  +DTTGAGD+F+ AL   +     L L  +   +N +AA+S Q  G 
Sbjct: 228 --TVVDVPSYNVNPLDTTGAGDAFMAALLVGILKLKGLDLLKLGKFANLVAALSTQKRGA 285

Query: 308 QSSYPYKKDL 317
            S+ P K +L
Sbjct: 286 WST-PRKDEL 294


>3GO6-A nrPDB
          Length = 310

 Score = 64.7 bits (156), Expect = 5e-11,   Method: Compositional matrix adjust.
 Identities = 83/275 (30%), Positives = 115/275 (41%), Gaps = 29/275 (10%)

Query: 18  VVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGK 77
           V VVGS   DL  +   LP+ GET+         GGKGANQ V AAR GA        G 
Sbjct: 22  VCVVGSVNMDLTFVVDALPRPGETVLAASLTRTPGGKGANQAVAAARAGAQVQFSGAFGD 81

Query: 78  DSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDLR 137
           D        +L+ N +  + T  T    +GTA I+V+   +N +++  GAN       L 
Sbjct: 82  DPAAAQLRAHLRANAVGLDRTV-TVPGPSGTAIIVVDASAENTVLVAPGAN-----AHLT 135

Query: 138 AAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDP--QFYTLSDV 195
              + ++   V++ QLEI  AT+L A   A+ +    + N +PA  D         ++DV
Sbjct: 136 PVPSAVANCDVLLTQLEIPVATALAAARAAQSADAVVMVNASPAGQDRSSLQDLAAIADV 195

Query: 196 FCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIP 255
              NE EA           +      + L  RG + V    GA+G             +P
Sbjct: 196 VIANEHEANDWP-------SPPTHFVITLGVRGARYV----GADGVF----------EVP 234

Query: 256 TEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDM 290
              V  VDT GAGD F G LA      P    E +
Sbjct: 235 APTVTPVDTAGAGDVFAGVLAANWPRNPGSPAERL 269


>3KZH-A nrPDB
          Length = 328

 Score = 64.3 bits (155), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 67/296 (22%), Positives = 126/296 (42%), Gaps = 17/296 (5%)

Query: 18  VVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGK 77
           ++V G+ + D+   +    +   +  GH   I FGG   N     AR+G  T+ +  +G 
Sbjct: 9   LLVFGASVVDVFGFSKASYRPYNSTPGH-VKISFGGVCRNIAENMARVGVNTNFMSILGN 67

Query: 78  DSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANL-LLNTEDL 136
           D  G   +E+ K+     + +   +  +T T   I++  G+ +  I    ++  +NT+ +
Sbjct: 68  DEHGKSIVEHSKKIGYHMDDSMVIEGGSTPTYLAILDENGEMVSAIADMKSIGAMNTDFI 127

Query: 137 RAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPA-----IADLDPQFYT 191
            +   +   A+  V  L+      +E L    +     + +P  A     +  L   F+T
Sbjct: 128 DSKREIFENAEYTV--LDSDNPEIMEYLLKNFKDKTNFILDPVSAEKASWVKHLIKDFHT 185

Query: 192 LSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEP 251
           +      N  EAEIL G  +    D  +A+   L  G + V I+L A+G  +        
Sbjct: 186 IK----PNRHEAEILAGFPITDTDDLIKASNYFLGLGIKKVFISLDADG--IFYNDGVSC 239

Query: 252 KHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGT 307
             I   +V   + TGAGDSFV  L +   Y   + +ED++  +  ++ +++    T
Sbjct: 240 GKIKATEVDVKNVTGAGDSFVAGLGY--GYMNKMPIEDIVKFAMTMSNITISHEET 293


>5EYN-A nrPDB
          Length = 323

 Score = 64.3 bits (155), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 67/291 (23%), Positives = 127/291 (43%), Gaps = 41/291 (14%)

Query: 52  GGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASI 111
           GG  AN  V  ARL   ++   +VG D FG    + L    +  +  +      T T  +
Sbjct: 44  GGAPANVAVAIARLSGRSAFFGRVGNDPFGRFMQQTLTDEQVDCQHLHFDPVHRTSTVVV 103

Query: 112 IVNNEGQN--IIVIVAGANLLLNTEDLRAAANVISRAKVMVCQLEI----TPATSLEALT 165
            ++  G+     ++   A+  L   D+    +      + VC + +    + +++  A+ 
Sbjct: 104 DLDEHGERSFTFMVKPSADQFLQLSDI---PSFQKGEWLHVCSIALANQPSRSSTFAAIA 160

Query: 166 MARRSGVKTLFNPAPAIADLDPQFYT--------------LSDVFCCNESEAEILTGLTV 211
             +  G    F+P     +L  + ++              L+DV   +E E + LTG   
Sbjct: 161 QMKEVGGYVSFDP-----NLREEVWSEPQELQATVMRAVGLADVVKFSEEELQFLTGT-- 213

Query: 212 GSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPTEK-VKAVDTTGAGDS 270
             + + G  A+   +    +V++TLGA+G +V +   P  + I + K VK +DTTGAGD+
Sbjct: 214 -QSIEEGLQAIADFQ--IPLVVVTLGAKGALVAT---PNSQQIVSGKAVKPIDTTGAGDA 267

Query: 271 FVGALAFYLA----YYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPYKKDL 317
           FVG L + L+    ++   ++ D +  +N   A++    G  ++ P +  L
Sbjct: 268 FVGGLLYRLSVAQDWHNQATILDAVKWANGCGALATTQKGAMTALPNQAAL 318


>1V1S-A nrPDB
          Length = 309

 Score = 62.8 bits (151), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 87/324 (26%), Positives = 126/324 (38%), Gaps = 46/324 (14%)

Query: 18  VVVVGSCMTDLVSLTSRLPKTGETIHGHKFF-IGFGGKGANQCVQAARLGAMTSMVCKVG 76
           VV  G  +  LV      P+    + G +   +  GG   N  V  ARLG     V +VG
Sbjct: 4   VVTAGEPLVALV------PQEPGHLRGKRLLEVYVGGAEVNVAVALARLGVKVGFVGRVG 57

Query: 77  KDSFGNDYIENLKQNDIS-TEFT--------YQTKDAATGTASIIVNNEGQNIIVIVAGA 127
           +D  G    E L+   +  T F         Y  +    G   +    +G     +  GA
Sbjct: 58  EDELGAMVEERLRAEGVDLTHFRRAPGFTGLYLREYLPLGQGRVFYYRKGSAGSALAPGA 117

Query: 128 NLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVK---------TLFNP 178
                  D       +  + +         A SL A+  A+R GV+         TL++P
Sbjct: 118 F----DPDYLEGVRFLHLSGITPALSPEARAFSLWAMEEAKRRGVRVSLDVNYRQTLWSP 173

Query: 179 APAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGA 238
             A   L+     + D+   +E EAE+L G  V  A  A  A  V+LKRG +      GA
Sbjct: 174 EEARGFLERALPGV-DLLFLSEEEAELLFG-RVEEALRALSAPEVVLKRGAK------GA 225

Query: 239 EGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLA-YYPNLSLEDMLNRSNFI 297
              V   + E          V+AVD  GAGD+F    A YLA     L +E+ L  +N +
Sbjct: 226 WAFVDGRRVEGS-----AFAVEAVDPVGAGDAFA---AGYLAGAVWGLPVEERLRLANLL 277

Query: 298 AAVSVQAAGTQSSYPYKKDLPLTL 321
            A    + G     PY++DL + L
Sbjct: 278 GASVAASRGDHEGAPYREDLEVLL 301


>3UBO-A nrPDB
          Length = 354

 Score = 61.6 bits (148), Expect = 4e-10,   Method: Compositional matrix adjust.
 Identities = 73/277 (26%), Positives = 113/277 (40%), Gaps = 39/277 (14%)

Query: 52  GGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTK----DAATG 107
           GG   N     A LG   +   KV  D  G  +  +++   +     +QTK       T 
Sbjct: 60  GGSAGNTAAGVASLGGRAAYFGKVADDQLGEIFTHDIRAQGVH----FQTKPLDGHPPTA 115

Query: 108 TASIIVNNEGQNIIVIVAGANLLLNTEDLRAAANVISRAKVMVCQLEI-TPATSLEALTM 166
            + I V  +G+  +    GA + L  ED+    +V++++KV   +  +  P  + +A+  
Sbjct: 116 RSMIFVTEDGERSMNTYLGACVELGPEDVED--DVVAQSKVTYFEGYLWDPPRAKDAIRE 173

Query: 167 ARRSGVKTLFNPAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSA----ADAGEA-- 220
           A R           A A       TLSD FC +   +E L  +  G+     A+  EA  
Sbjct: 174 AARI----------AHAHGRETAMTLSDSFCVHRYRSEFLELMRSGTVDIVFANRQEALA 223

Query: 221 ---------ALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSF 271
                    AL LL R C++  +TL  EG VV+   E   +   +   + VDTTGAGD +
Sbjct: 224 LYETEDFDRALELLARDCKLAAVTLSEEGSVVVRGAE-RVRVGASVLEQVVDTTGAGDLY 282

Query: 272 VGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQ 308
             A  F   Y    SLE+     N  A + +   G +
Sbjct: 283 --AAGFLFGYTSGRSLEECSKLGNLAAGIVIGQIGPR 317


>3H49-A nrPDB
          Length = 325

 Score = 58.9 bits (141), Expect = 3e-09,   Method: Compositional matrix adjust.
 Identities = 72/275 (26%), Positives = 125/275 (45%), Gaps = 22/275 (8%)

Query: 52  GGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASI 111
           GG   N+    +RLG  T+++ ++GKD+ G   +++ ++ +I  +   Q     T     
Sbjct: 43  GGDAINEATIISRLGHRTALMSRIGKDAAGQFILDHCRKENIDIQSLKQDVSIDTSINVG 102

Query: 112 IVNNEGQNIIVIVAGANLL-LNTEDLRAAANVISRAKVM-VCQLEITPATSLEALT-MAR 168
           +V  +G+   V     +L  LN +D+  A    S+AK++ +  +  +P    +ALT +  
Sbjct: 103 LVTEDGERTFVTNRNGSLWKLNIDDVDFAR--FSQAKLLSLASIFNSPLLDGKALTEIFT 160

Query: 169 RSGVKTLFNPAPAIA-----DLDPQFYTLS--DVFCCNESEAEILTGL-TVGSAADAGEA 220
           ++  + +   A  I       LD     LS  D    N +EA++LTG  T+   AD    
Sbjct: 161 QAKARQMIICADMIKPRLNETLDDICEALSYVDYLFPNFAEAKLLTGKETLDEIADC--- 217

Query: 221 ALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLA 280
               L  G + V+I  G +GC +  + +   K      + A+DT GAGD+F  A  F  A
Sbjct: 218 ---FLACGVKTVVIKTGKDGCFI-KRGDMTMKVPAVAGITAIDTIGAGDNF--ASGFIAA 271

Query: 281 YYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPYKK 315
                +L +    +N  AA+SV + G  +    +K
Sbjct: 272 LLEGKNLRECARFANATAAISVLSVGATTGVKNRK 306


>4LC4-A nrPDB
          Length = 352

 Score = 58.2 bits (139), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 70/282 (24%), Positives = 109/282 (38%), Gaps = 49/282 (17%)

Query: 52  GGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAA----TG 107
           GG   N     A LG   +    V  D  G+ +  +++   +     YQTK       T 
Sbjct: 80  GGSAGNTAAGVANLGGKAAYFGNVAADQLGDIFTHDIRAQGVH----YQTKPKGAFPPTA 135

Query: 108 TASIIVNNEGQNIIVIVAGANLLLNTEDLRAAANVISRAKVMVCQLEI-TPATSLEAL-- 164
            + I V  +G+  +    GA + L  ED+ A  +V++ AKV   +  +  P  + EA+  
Sbjct: 136 RSMIFVTEDGERSMNTYLGACVELGPEDVEA--DVVADAKVTYFEGYLWDPPRAKEAILD 193

Query: 165 --TMARRSGVKTLFNPAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSA-------- 214
              +A + G +                 TLSD FC +    E L  +  G          
Sbjct: 194 CARIAHQHGREMSM--------------TLSDSFCVDRYRGEFLDLMRSGKVDIVFANRQ 239

Query: 215 -------ADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPTEKVK-AVDTTG 266
                   D  E AL  +   C++  +T+   G V+L   E    ++   +++  VDTTG
Sbjct: 240 EALSLYQTDDFEEALNRIAADCKIAAVTMSENGAVILKGRER--YYVNAIRIREVVDTTG 297

Query: 267 AGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQ 308
           AGD F  A  F   Y    SLED        A + +Q  G +
Sbjct: 298 AGDLF--ASGFLYGYTQGRSLEDCGKLGCLAAGIVIQQIGPR 337


>2NWH-A nrPDB
          Length = 317

 Score = 58.2 bits (139), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 79/276 (28%), Positives = 122/276 (44%), Gaps = 28/276 (10%)

Query: 52  GGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDI-STEFTYQTKDAATGTAS 110
           GG G N     +RLG    ++   G D  G    E  +Q  +  T FT+  +   + TA 
Sbjct: 39  GGGGFNAARNLSRLGFEVRIIAPRGGDVTGEVVAEAARQAGVEDTPFTFLDRRTPSYTA- 97

Query: 111 IIVNNEGQNIIVIVAGANL--LLNTEDL--RAAANVISRAKVMVCQLEITPATSLEALTM 166
            I+  +G N+++ +A  +L  L     L  RA    I  +  ++C   + P  +L AL +
Sbjct: 98  -ILERDG-NLVIALADMDLYKLFTPRRLKVRAVREAIIASDFLLCDANL-PEDTLTALGL 154

Query: 167 ARRSGVKTL----FNPAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAAL 222
             R+  K L     +PA A+  L      + D+   NE+EA  LTG T  +  D      
Sbjct: 155 IARACEKPLAAIAISPAKAV-KLKAALGDI-DILFMNEAEARALTGETAENVRDWPN--- 209

Query: 223 VLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIP-TEKVKAVDTTGAGDSFVGALAFYLAY 281
           +L K G    ++T GA   V  + TE    H P   +VK  D TGAGD+   A  +  A 
Sbjct: 210 ILRKAGLSGGVVTRGASEVVAFNGTEKAILHPPLIREVK--DVTGAGDAM--ASGYLAAI 265

Query: 282 YPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPYKKDL 317
               ++ + L +    AA++V     QSS+   +DL
Sbjct: 266 AEGKTIREALRQGAAAAAITV-----QSSFATSQDL 296


>2RBC-A nrPDB
          Length = 343

 Score = 58.2 bits (139), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 70/269 (26%), Positives = 112/269 (41%), Gaps = 19/269 (7%)

Query: 18  VVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGK 77
           V+ VG+ + D +   + +PK    +  ++      G  ++      R+G   S+   VG 
Sbjct: 32  VLCVGAAVLDTLFRVADMPKGEGKVLPYEVLQIAEGMASSAAYAVHRMGGRASLWGAVGD 91

Query: 78  DSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDLR 137
           D  G   + +L ++ I T        A +  ++II++N G+ +IV      L    E  R
Sbjct: 92  DETGTRILRDLSESGIDTSGMTVAPGARSALSTIIIDNRGERLIVPFYDHRL---HEKKR 148

Query: 138 A-AANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFN----PAPAIADLDPQFYTL 192
           A     I+    ++  +   P  +L+ LT+AR  G   + +    P   +  L P    +
Sbjct: 149 ACTPEDIALFDAVLVDVRW-PELALDVLTVARALGKPAILDGDVAPVETLEGLAPAATHI 207

Query: 193 SDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVI-ITLGAEGCVVLSQTEPEP 251
             VF  +E  A  LTGL         +   VL  R  Q  I +T G  GC      +P  
Sbjct: 208 --VF--SEPAATRLTGLET-----VKDMLPVLHARYPQTFIAVTAGPAGCWWTEADDPTV 258

Query: 252 KHIPTEKVKAVDTTGAGDSFVGALAFYLA 280
               T +V+AVDT  AGD F G  A  +A
Sbjct: 259 HFQTTMQVEAVDTLAAGDIFHGTFALAMA 287


>4WJM-A nrPDB
          Length = 312

 Score = 53.9 bits (128), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 62/260 (23%), Positives = 98/260 (37%), Gaps = 36/260 (13%)

Query: 30  SLTSRLPKTGETIHGHKFFIGF-GGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENL 88
           +L   LP+  ET  G   F  F GG   N  +   RLG  T     +  D FG+   + L
Sbjct: 14  ALIDMLPR--ETTGGETAFQPFAGGSVFNTAIALGRLGVPTGFFSGISSDFFGDVLRDTL 71

Query: 89  KQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDLRAAANVISRAKV 148
            ++++   F   +    T     +V+ + +        A  +L+  D+      IS    
Sbjct: 72  ARSNVDYSFAAISNRPTTLAFVRLVDGQARYAFYDENTAGRMLSRNDMPYVDETISAMLF 131

Query: 149 MVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDP------------------QFY 190
               L   P  S+    +AR +  + +F        LDP                  +  
Sbjct: 132 GCISLISEPCGSVYETLLAREAPNRVMF--------LDPNIRANLITVRKTHLTRMKRMI 183

Query: 191 TLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPE 250
            L+D+   ++ + +       G      E A   LK G ++V+IT GA G V  +     
Sbjct: 184 ALADIVKLSDEDLDWF-----GEKGSHDEIAAEWLKLGPKLVVITKGAHGAVAYTNHATV 238

Query: 251 PKHIPTEKVKAVDTTGAGDS 270
           P  +P  KV  VDT GAGD+
Sbjct: 239 P--VPGVKVDVVDTVGAGDT 256


>2QCV-A nrPDB
          Length = 332

 Score = 53.1 bits (126), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 66/292 (22%), Positives = 122/292 (41%), Gaps = 52/292 (17%)

Query: 18  VVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGK 77
           ++ +G    DL ++    P   ET+   K+    GG  AN  + +++LG     + K+  
Sbjct: 14  LIAIGRACIDLNAVEYNRPME-ETMTFSKYV---GGSPANIVIGSSKLGLKAGFIGKIAD 69

Query: 78  DSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQN----------------II 121
           D  G  +IE+              +     T++++V+ EG                  ++
Sbjct: 70  DQHGR-FIESY------------MRGVGVDTSNLVVDQEGHKTGLAFTEIKSPEECSILM 116

Query: 122 VIVAGANLLLNTEDLRAAANVISRAKVMVCQ---LEITPATS--LEALTMARRSGVKTLF 176
                A+L L+ E++  A   I R+K+++     L  +P+    L+A+ +A+R+ VK +F
Sbjct: 117 YRQDVADLYLSPEEVNEA--YIRRSKLLLVSGTALSKSPSREAVLKAIRLAKRNDVKVVF 174

Query: 177 --NPAPAIADLDPQ---FYTL----SDVFCCNESEAEILTGLTVGSAADAGEAALVLLKR 227
             +  P   +   +   +Y+L    SD+      E ++L   T     D  E    L K 
Sbjct: 175 ELDYRPYSWETPEETAVYYSLVAEQSDIVIGTREEFDVLENRT--EKGDNDETIRYLFKH 232

Query: 228 GCQVVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYL 279
             ++++I  G EG    ++   E       K K + T GAGDS+  A  + L
Sbjct: 233 SPELIVIKHGVEGSFAYTKA-GEAYRGYAYKTKVLKTFGAGDSYASAFLYAL 283


>2QHP-A nrPDB
          Length = 296

 Score = 53.1 bits (126), Expect = 2e-07,   Method: Compositional matrix adjust.
 Identities = 65/244 (26%), Positives = 102/244 (41%), Gaps = 34/244 (13%)

Query: 52  GGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASI 111
           GG  AN     ++ G  + +V  VG D  G++ +E  K+  +  +   +  D  TGT  +
Sbjct: 24  GGAPANFAYHVSQFGFDSRVVSAVGNDELGDEIMEVFKEKQLKNQI--ERVDYPTGTVQV 81

Query: 112 IVNNEGQNIIVI---VAGANLLLNTEDLRAAANVISRAKVMVC------QLEITPATSLE 162
            +++EG     I   VA  N+    E  R A N  +RA   VC      + E++ AT   
Sbjct: 82  TLDDEGVPCYEIKEGVAWDNIPFTDELKRLALN--TRA---VCFGSLAQRNEVSRATINR 136

Query: 163 AL-TMARRSGVKTLFNPAPAIADLDPQFYTLS---------DVFCCNESEAEILTGLTVG 212
            L TM    G   +F+      +L   FYT           ++   N+ E   ++ +   
Sbjct: 137 FLDTMPDIDGQLKIFD-----INLRQDFYTKEVLRESFKRCNILKINDEELVTISRMFGY 191

Query: 213 SAADAGEAALVLL-KRGCQVVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSF 271
              D  +   +LL K   +++I+T G  G  V +      +  P  KV   DT GAGDSF
Sbjct: 192 PGIDLQDKCWILLAKYNLKMLILTCGINGSYVFTPGVVSFQETP--KVPVADTVGAGDSF 249

Query: 272 VGAL 275
             A 
Sbjct: 250 TAAF 253


>3IQ0-A nrPDB
          Length = 330

 Score = 51.2 bits (121), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 57/235 (24%), Positives = 95/235 (40%), Gaps = 36/235 (15%)

Query: 61  QAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNI 120
           Q  RLG    ++  VG D FG+  I  L  + +           ATG+A +  +N G   
Sbjct: 46  QVTRLGVPCGIISCVGNDGFGDINIHRLAADGVDIRGISVLPLEATGSAFVTYHNSGDR- 104

Query: 121 IVIVAGANLLLNTEDL---RAAANVISRAKVMVCQLEITPATSL----------EALTMA 167
                  + + N ++    + +A  +    +  C       +SL          +A+T+ 
Sbjct: 105 -------DFIFNIKNAACGKLSAQHVDENILKDCTHFHIMGSSLFSFHMVDAVKKAVTIV 157

Query: 168 RRSGVKTLFNP--------APAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGE 219
           + +G    F+P         P + D       L+D++  +E E  +L+  +    A AG 
Sbjct: 158 KANGGVISFDPNIRKEMLDIPEMRDALHFVLELTDIYMPSEGEVLLLSPHSTPERAIAG- 216

Query: 220 AALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGA 274
                L+ G + VI+  G +G    S  E    H+ +  V+ VD TGAGD F GA
Sbjct: 217 ----FLEEGVKEVIVKRGNQGASYYSANEQ--FHVESYPVEEVDPTGAGDCFGGA 265


>2I6B-A nrPDB
          Length = 345

 Score = 50.4 bits (119), Expect = 9e-07,   Method: Compositional matrix adjust.
 Identities = 60/264 (22%), Positives = 110/264 (41%), Gaps = 30/264 (11%)

Query: 75  VGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTE 134
           +G D FG        +  +   + Y+  +  TGT +  +  + +++I  +A AN     +
Sbjct: 90  IGIDKFGEILKRKAAEAHVDAHY-YEQNEQPTGTCAACITGDNRSLIANLAAANCYKKEK 148

Query: 135 DLRAAANVISRAKVMVCQ-----LEITPATSLEALTMARRSG-VKTLFNPAPAIADLDPQ 188
            L    N +   K  VC      L ++P + L+    A  +  + TL   AP I+    Q
Sbjct: 149 HLDLEKNWMLVEKARVCYIAGFFLTVSPESVLKVAHHASENNRIFTLNLSAPFIS----Q 204

Query: 189 FYTLS--------DVFCCNESEAEILT---GLTVGSAADAGEAALVLLK---RGCQVVII 234
           FY  S        D+   NE+EA       G       +  +    L K   +  ++VI 
Sbjct: 205 FYKESLMKVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKTQALPKMNSKRQRIVIF 264

Query: 235 TLGAEGCVVLSQTEPEPKHIPTEKVKAV-DTTGAGDSFVGALAFYLAYYPNLSLEDMLNR 293
           T G +  ++ +++E     +  +  K + DT GAGD+FVG   F      +  L + +  
Sbjct: 265 TQGRDDTIMATESEVTAFAVLDQDQKEIIDTNGAGDAFVG--GFLSQLVSDKPLTECIRA 322

Query: 294 SNFIAAVSVQAAGTQSSYPYKKDL 317
            ++ A++ ++  G   ++P K D 
Sbjct: 323 GHYAASIIIRRTG--CTFPEKPDF 344


>3PL2-A nrPDB
          Length = 319

 Score = 48.1 bits (113), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 72/272 (26%), Positives = 114/272 (41%), Gaps = 39/272 (14%)

Query: 51  FGGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEF--TYQTKDAATGT 108
            GG  AN  V AAR G  ++++ +VG D FG   +  L++  +  ++  T QT       
Sbjct: 40  LGGSAANVSVAAARHGHNSALLSRVGNDPFGEYLLAELERLGVDNQYVATDQTFKTPVTF 99

Query: 109 ASIIVNNEGQNIIVIVAGANLLLNTEDLRAAANVISRAKVMVCQL-----EITPATSLEA 163
             I   ++          A  L N E    + + +  A ++   L     E +  T  E 
Sbjct: 100 CEIFPPDDFPLYFYREPKAPDL-NIESADVSLDDVREADILWFTLTGFSEEPSRGTHREI 158

Query: 164 LTMARRSGVKTLFNPAPAIADLDPQFY--------------TLSDVFCCNESEAEILTGL 209
           LT  R +   T+F+      D  P F+                S V   N+ E EI  G 
Sbjct: 159 LT-TRANRRHTIFD-----LDYRPMFWESPEEATKQAEWALQHSTVAVGNKEECEIAVGE 212

Query: 210 TVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGD 269
           T     +   A   LL+RG ++ I+  G +G  V++ T+ E   +P   V  ++  GAGD
Sbjct: 213 T-----EPERAGRALLERGVELAIVKQGPKG--VMAMTKDETVEVPPFFVDVINGLGAGD 265

Query: 270 SFVGALAF-YLAYYPNLSLEDMLNRSNFIAAV 300
           +F GAL    L+ +P   LE +L  +N   A+
Sbjct: 266 AFGGALCHGLLSEWP---LEKVLRFANTAGAL 294


>3LJS-A nrPDB
          Length = 338

 Score = 47.8 bits (112), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 63/249 (25%), Positives = 102/249 (40%), Gaps = 31/249 (12%)

Query: 52  GGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASI 111
           GG  AN  V  ARLG     V  +G D FG+   ++  +  + T+   +T  A T  A +
Sbjct: 36  GGAPANVAVAVARLGGAVQFVGMLGSDMFGDFLFDSFAEAGVVTDGIVRTSTAKTALAFV 95

Query: 112 IVNNEGQNIIVIV--AGANLLLNTEDLRAAANVISRAKVM-VCQLEITPA----TSLEAL 164
            ++  G+          A+LL   E  + A+   S A +   C   +T A     + E +
Sbjct: 96  ALDAHGERSFSFYRPPAADLLFRVEHFQDAS--FSDALIFHACSNSMTDADIAEVTFEGM 153

Query: 165 TMARRSGVKTLF-------------NPAPAIADLDPQFYTLSDVFCCNESEAEILTGLTV 211
             A+ +G    F             NPA  +     +  +L+DV   +  E + L     
Sbjct: 154 RRAQAAGAIVSFDLNFRPMLWPNGENPASRLW----KGLSLADVVKLSSEELDYLANTL- 208

Query: 212 GSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSF 271
             AADA      L +   Q++++T  A    V   T      +PT +V+  D+  AGD+F
Sbjct: 209 --AADANAVIQQLWQGRAQLLLVTDAA--GPVHWYTRTAGGEVPTFRVQVQDSNAAGDAF 264

Query: 272 VGALAFYLA 280
           VG + +  A
Sbjct: 265 VGGMLYTFA 273


>2C4E-A nrPDB
          Length = 302

 Score = 47.4 bits (111), Expect = 7e-06,   Method: Compositional matrix adjust.
 Identities = 71/312 (22%), Positives = 118/312 (37%), Gaps = 40/312 (12%)

Query: 14  EVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVC 73
           ++  +  VG    D +    + P+   +I        +GG  AN  V   +LG  + ++ 
Sbjct: 4   KMEKITCVGHTALDYIFNVEKFPEPNTSIQIPSARKYYGGAAANTAVGIKKLGVNSELLS 63

Query: 74  KVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLL--- 130
            VG D   + Y   LK  DI+    Y +++  T  A I  + +   I   + GA      
Sbjct: 64  CVGYDFKNSGYERYLKNLDINISKLYYSEEEETPKAWIFTDKDNNQITFFLWGAAKHYKE 123

Query: 131 -----LNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADL 185
                 NTE +  A                 P  +L+    A  + + + F+P   +   
Sbjct: 124 LNPPNFNTEIVHIATG--------------DPEFNLKCAKKAYGNNLVS-FDPGQDLPQY 168

Query: 186 DPQFY----TLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGC 241
             +        ++    N+ E E  + L      D        L+R    +I+T G++G 
Sbjct: 169 SKEMLLEIIEHTNFLFMNKHEFERASNLLNFEIDD-------YLER-VDALIVTKGSKGS 220

Query: 242 VVLSQTEPEPKHIPTEKV-KAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAV 300
           V+   T+ +   IP  K  K +D TGAGDS+     F  AY     LE         A+ 
Sbjct: 221 VIY--TKDKKIEIPCIKAGKVIDPTGAGDSYRA--GFLSAYVKGYDLEKCGLIGAATASF 276

Query: 301 SVQAAGTQSSYP 312
            V+A G Q++ P
Sbjct: 277 VVEAKGCQTNLP 288


>3N1C-A nrPDB
          Length = 309

 Score = 47.0 bits (110), Expect = 1e-05,   Method: Compositional matrix adjust.
 Identities = 64/261 (24%), Positives = 106/261 (40%), Gaps = 41/261 (15%)

Query: 52  GGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASI 111
           GG G N     A LG   + +   G  + G   +  L   ++    T + KD       +
Sbjct: 38  GGGGINVARAIAHLGGSATAIFPAG-GATGEHLVSLLADENVPVA-TVEAKDWTRQNLHV 95

Query: 112 IVNNEGQNIIVIVAGANLLLNTEDLRAAANV---ISRAKVMVCQLEITPATSLEALTM-- 166
            V   G+    ++ GA   LN ++ R        I    ++V    + P   LE LT   
Sbjct: 96  HVEASGEQYRFVMPGA--ALNEDEFRQLEEQVLEIESGAILVISGSLPPGVKLEKLTQLI 153

Query: 167 --ARRSGVKTL-------FNPAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADA 217
             A++ G++ +        + A AI +++        +   N+ E   L    +    D 
Sbjct: 154 SAAQKQGIRCIVDSSGEALSAALAIGNIE--------LVKPNQKELSALVNRELTQPDDV 205

Query: 218 GEAALVLLKRG-CQVVIITLGAEGCVVLS-----QTEPEPKHIPTEKVKAVDTTGAGDSF 271
            +AA  ++  G  + V+++LG +G + +      Q  P P       VK+  T GAGDS 
Sbjct: 206 RKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQVVPPP-------VKSQSTVGAGDSM 258

Query: 272 VGALAFYLAYYPNLSLEDMLN 292
           VGA+   LA   N SLE+M+ 
Sbjct: 259 VGAMTLKLAE--NASLEEMVR 277


>4DU5-A nrPDB
          Length = 336

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 73/330 (22%), Positives = 113/330 (34%), Gaps = 57/330 (17%)

Query: 18  VVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGK 77
           V+  G  M  LV+      + G   H   F     G   N  +  ARLG       ++G 
Sbjct: 29  VITFGEAMMLLVA-----DRPGPLEHAEAFHKRTAGAETNVAIGLARLGLKVGWASRLGT 83

Query: 78  DSFGNDYIENLKQNDIS-----------TEFTYQTKDAATGTASIIVNNEGQNIIVIVAG 126
           DS G   +  +    I            T F ++ K        +  + +G         
Sbjct: 84  DSMGRYLLAAMAAEGIDCSHVVCDATQKTGFQFKGKVTDGSDPPVEYHRKGS-------- 135

Query: 127 ANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEA----LTMARRSGVKTLFNPAPAI 182
           A   +   D+  A  + +R            AT+L A    + + R +G    F+P    
Sbjct: 136 AASHMGVADIDEAWLLSARHLHATGVFPAISATTLPAARKTMDLMRAAGRSVSFDP---- 191

Query: 183 ADLDPQFY--------------TLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRG 228
            +L P  +              T +D       E   LTG T          A    + G
Sbjct: 192 -NLRPTLWATPELMRDAINDLATRADWVLPGMEEGRFLTGETTPEGV-----ARFYRQLG 245

Query: 229 CQVVIITLGAEGCVVLSQT-EPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSL 287
            ++V++ LGAEG     +         P  +V  VDT GAGD F  A+    A    L +
Sbjct: 246 AKLVVVKLGAEGAYFDGEAGSGRVAGFPVAEV--VDTVGAGDGF--AVGVISALLDGLGV 301

Query: 288 EDMLNRSNFIAAVSVQAAGTQSSYPYKKDL 317
            + + R  +I A +VQ  G     P + +L
Sbjct: 302 PEAVKRGAWIGARAVQVLGDSEGLPTRAEL 331


>3LHX-A nrPDB
          Length = 319

 Score = 46.2 bits (108), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 78/318 (24%), Positives = 122/318 (38%), Gaps = 52/318 (16%)

Query: 18  VVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARL---GAMT-SMVC 73
           + V+G CM +L    + + +            GFGG   N  V  AR     A+T   V 
Sbjct: 7   IAVIGECMIELSEKGADVKR------------GFGGDTLNTSVYIARQVDPAALTVHYVT 54

Query: 74  KVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIV---AGANLL 130
            +G DSF    ++     ++ T  T + ++   G   I  ++ G+         A A   
Sbjct: 55  ALGTDSFSQQMLDAWHGENVDTSLTQRMENRLPGLYYIETDSTGERTFYYWRNEAAAKFW 114

Query: 131 LNTEDLRAAANVISRAKVMV---CQLEITPATSLEAL----TMARRSGVKTLF--NPAPA 181
           L +E   A    ++    +      L I   TS E L       R  G K +F  N  P 
Sbjct: 115 LASEQSAAICEELANFDYLYLSGISLAILSPTSREKLLSLLRECRAKGGKVIFDNNYRPR 174

Query: 182 I-------ADLDPQFYTLSDVFCCNESEAEILTGL-----TVGSAADAGEAALVLLKRGC 229
           +         +  Q    +D+      + + L G       +    +AG    V++KRG 
Sbjct: 175 LWASKEETQQVYQQMLECTDIAFLTLDDEDALWGQQPVEDVIARTHNAG-VKEVVVKRGA 233

Query: 230 QVVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSF-VGALAFYLAYYPNLSLE 288
              ++++  E  V +    P  K +P EKV  +DTT AGDSF  G LA  L      S E
Sbjct: 234 DSCLVSIAGEALVDV----PAVK-LPKEKV--IDTTAAGDSFSAGYLAVRLT---GGSAE 283

Query: 289 DMLNRSNFIAAVSVQAAG 306
           +   R +  A+  +Q  G
Sbjct: 284 NAAKRGHLTASTVIQYRG 301


>1WYE-A nrPDB
          Length = 311

 Score = 45.8 bits (107), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 69/322 (21%), Positives = 126/322 (39%), Gaps = 39/322 (12%)

Query: 15  VAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCK 74
           +A ++ +G  + +  +L+      G   H   F     G  AN CV   + G    ++ K
Sbjct: 1   MAKLITLGEILIEFNALS-----PGPLRHVSYFEKHVAGSEANYCVAFIKQGNECGIIAK 55

Query: 75  VGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASII----VNNEGQNIIVIVAGANLL 130
           VG D FG + IE L+   +          A TG   I     V  + ++I      A   
Sbjct: 56  VGDDEFGYNAIEWLRGQGVDVSHMKIDPSAPTGIFFIQRHYPVPLKSESIYYRKGSAGSK 115

Query: 131 LNTEDLR----AAANVISRAKVMVCQLEITPATSLEALTMARRSGVKT-----LFNPAPA 181
           L+ ED+      +A+++  + + +           +A  +A      T     L++   A
Sbjct: 116 LSPEDVDEEYVKSADLVHSSGITLAISSTAKEAVYKAFEIASNRSFDTNIRLKLWSAEEA 175

Query: 182 ---IADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGA 238
              I  L  +F+        +  +++I+ G      +D  +AA        +++++ LG 
Sbjct: 176 KREILKLLSKFHL--KFLITDTDDSKIILG-----ESDPDKAAKAFSDY-AEIIVMKLGP 227

Query: 239 EGCVVL---SQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSN 295
           +G +V     +       +P E     D TGAGD+  G   F   YY    +E  L+ + 
Sbjct: 228 KGAIVYYDGKKYYSSGYQVPVE-----DVTGAGDALGGT--FLSLYYKGFEMEKALDYAI 280

Query: 296 FIAAVSVQAAGTQSSYPYKKDL 317
             + ++V   G Q + P  KD+
Sbjct: 281 VASTLNVMIRGDQENLPTTKDI 302


>3LOO-A nrPDB
          Length = 365

 Score = 44.7 bits (104), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 57/223 (25%), Positives = 96/223 (43%), Gaps = 27/223 (12%)

Query: 75  VGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTE 134
           VG+D +     E    N ++ ++  ++  + TGT +++V    +++   +A AN     E
Sbjct: 106 VGQDEYARILEERATSNGVNVQYQ-RSATSPTGTCAVLVTGTQRSLCANLAAANDF-TPE 163

Query: 135 DLRAAANVISRAKVMVCQLEITPA----TSLE-ALTMARRSGVKTLFNPAPAIADLDPQF 189
            LR+  N   RA +   Q           S E AL++A+ +            A   PQF
Sbjct: 164 HLRSDGN---RAYLQGAQFFYVSGFFFTVSFESALSVAKEAAATGRMFMMNLSAPFVPQF 220

Query: 190 YT--------LSDVFCCNESEAEILTG-LTVGSA--ADAGEAALVLLK---RGCQVVIIT 235
           Y           DV   NE+EA  L      G+    + G+    L K   +  ++VIIT
Sbjct: 221 YKNNLEEIFPYVDVLFGNETEAIALAKEFNYGTEDLREIGKRIAALPKENGKRKRIVIIT 280

Query: 236 LGAEGCVVLSQTEPEPKHIPTEKV---KAVDTTGAGDSFVGAL 275
            G++  +++       +  P +K+   + VDT GAGD+FVG  
Sbjct: 281 QGSDPVLLIEAGTDNVREFPVQKLAPEQMVDTNGAGDAFVGGF 323


>2JG5-A nrPDB
          Length = 306

 Score = 43.9 bits (102), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 31/100 (31%), Positives = 51/100 (51%), Gaps = 12/100 (12%)

Query: 199 NESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPTEK 258
           N+ E E++   TV S AD  +   +L+ +G Q VI++LG +G + +       K I  + 
Sbjct: 181 NKDELEVMFNTTVNSDADVIKYGRLLVDKGAQSVIVSLGGDGAIYID------KEISIKA 234

Query: 259 V----KAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRS 294
           V    K V+T G+GDS V  +   +A    LS+E    ++
Sbjct: 235 VNPQGKVVNTVGSGDSTVAGMVAGIA--SGLSIEKAFQQA 272


>4N08-A nrPDB
          Length = 348

 Score = 41.6 bits (96), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 66/289 (22%), Positives = 116/289 (40%), Gaps = 36/289 (12%)

Query: 52  GGKGAN-----QCVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAAT 106
           GG G N     Q +Q A  G   + V  +  D +G    E  +   I     + TK A +
Sbjct: 65  GGSGLNVARVAQWMQQAYKGKFVTYVGCIADDRYGKVLKEAAEHEGIVMAVEHTTK-AGS 123

Query: 107 GTASIIVNNEGQNIIVIVAGANLLLNTEDLRAAANV--ISRAKVMVCQ---LEITPATSL 161
           G  ++ +  + + ++  +  AN L ++E +R+ A V  +  +++       L +     L
Sbjct: 124 GACAVCITGKERTLVADLGAANHL-SSEHMRSPAVVRAMDESRIFYFSGFTLTVDVNHVL 182

Query: 162 EALTMARR-SGVKTLFNPAPAIADLDPQFYT--------LSDVFCCNESEAEILTGLT-- 210
           +A   AR   G+  +   AP I     QF++         +D+   N  EA+    +   
Sbjct: 183 QACRKAREVDGLFMINLSAPFIM----QFFSAQLGEVLPYTDIIVANRHEAKEFANMMKW 238

Query: 211 ----VGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPT-EKVKAVDTT 265
               V   A    + +       +VV+ T   E  V+ ++   E   +P  ++ K +D  
Sbjct: 239 DTDCVEEIARRAVSEVPYTGTKGRVVVFTRDIESTVLATKDGVETVPVPQLDQDKVIDMN 298

Query: 266 GAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPYK 314
           GAGD+F+G   F  AY     L       ++ A   +Q  G   S+P K
Sbjct: 299 GAGDAFMG--GFLSAYAVGKDLRRCCETGHYTAQEVIQRDGC--SFPEK 343


>5KB6-A nrPDB
          Length = 363

 Score = 41.6 bits (96), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 59/264 (22%), Positives = 111/264 (42%), Gaps = 30/264 (11%)

Query: 75  VGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTE 134
           +G D FG           +   + Y+  +  TGT +  +    ++++  +A AN     +
Sbjct: 108 IGIDKFGEILKRKAADAHVDAHY-YEQNEQPTGTCAACITGGNRSLVANLAAANCYKKEK 166

Query: 135 DLRAAAN--VISRAKVMVCQ---LEITPATSLE-ALTMARRSGVKTLFNPAPAIADLDPQ 188
            L    N  ++ +A+V       L ++P + L+ A   A  + V TL   AP I+    Q
Sbjct: 167 HLDLERNWVLVEKARVYYIAGFFLTVSPESVLKVARYAAENNRVFTLNLSAPFIS----Q 222

Query: 189 FYTLS--------DVFCCNESEAEILT---GLTVGSAADAGEAALVLLK---RGCQVVII 234
           F+  +        D+   NE+EA       G       +  + A  L K   +  + VI 
Sbjct: 223 FFKEALMDVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIF 282

Query: 235 TLGAEGCVVLSQTEPEPKHIPTE-KVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNR 293
           T G +  +V ++ +     +  + + + +DT GAGD+FVG   F      +  L + +  
Sbjct: 283 TQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVG--GFLSQLVSDKPLTECIRA 340

Query: 294 SNFIAAVSVQAAGTQSSYPYKKDL 317
            ++ A+V ++  G   ++P K D 
Sbjct: 341 GHYAASVIIRRTGC--TFPEKPDF 362


>2HW1-A nrPDB
          Length = 298

 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 57/287 (19%), Positives = 110/287 (38%), Gaps = 39/287 (13%)

Query: 14  EVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVC 73
           E   ++ VG  + D++SL  + PK    I         GG  +N C   + LGA  + + 
Sbjct: 2   EEKQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMG 61

Query: 74  KVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNT 133
            +      +  +++L++  +   +T      +   A++I+N          +G+  +L  
Sbjct: 62  SMAPGHVADFVLDDLRRYSVDLRYTVFQTTGSVPIATVIINE--------ASGSRTILYY 113

Query: 134 EDLRAAANVISRAKVMVCQ---LEITPATSLEALTMARRSGVKTLFNPAP-----AIADL 185
           +      +     KV + Q   + I    + E + M +R        P       ++   
Sbjct: 114 DRSLPDVSATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVE 173

Query: 186 DP-----QFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVII------ 234
            P     Q +   DV   ++   ++   L   SA +A       +++G  +V        
Sbjct: 174 KPREELFQLFGYGDVVFVSK---DVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGA 230

Query: 235 -TLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLA 280
             LG +G ++ S   P P        + VDT GAGD+F  ++ F L+
Sbjct: 231 DALGPDGKLLHSDAFPPP--------RVVDTLGAGDTFNASVIFSLS 269


>3UQ9-A nrPDB
          Length = 372

 Score = 39.3 bits (90), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 65/267 (24%), Positives = 117/267 (43%), Gaps = 23/267 (8%)

Query: 70  SMVCKVGKDSFGNDYIEN-LKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGA- 127
           S V  +G D  G  YI+N     D+ TEF    +   TG  +++V+ + ++++  +  A 
Sbjct: 104 SYVGCIGADIQGK-YIKNDCSALDLVTEFQIAEEPLMTGKVAVLVSEKLRSMVTYLGAAC 162

Query: 128 NLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRS--GVKTL-FN-PAPAIA 183
           +L L   +     +++ +A+V      +        L +A+ S    K   FN  AP ++
Sbjct: 163 DLSLAHIEQPHVWSLVEKAQVYYIAGFVINTCYEGMLKIAKHSLENEKLFCFNLSAPFLS 222

Query: 184 DLD----PQFYTLSDVFCCNESEAE-------ILTGLTVGSAADAGEAALVLLKRGCQVV 232
             +     +  + S++   NESEAE       +L      +A    +      K+  ++V
Sbjct: 223 QFNTKEVDEMISYSNIVFGNESEAEAYGEVHGLLEDTVHATARYIADLPFADGKKRKRLV 282

Query: 233 IITLGAEGCVVLSQTEPEPKHIPTEKVK---AVDTTGAGDSF-VGALAFYLAYYPNL-SL 287
           IIT G    +    ++ E      E+ K    +DT GAGD+F  G +A Y+   P + SL
Sbjct: 283 IITRGKNPLLYTDSSDSEIHQFMVEQFKDDQIIDTNGAGDAFAAGFIADYIRGKPMITSL 342

Query: 288 EDMLNRSNFIAAVSVQAAGTQSSYPYK 314
              +  + +I   S  + G++ SY  K
Sbjct: 343 HAAVKAAAYIICRSGFSLGSRDSYSLK 369


>3KD6-A nrPDB
          Length = 313

 Score = 39.3 bits (90), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 31/99 (31%), Positives = 48/99 (48%), Gaps = 10/99 (10%)

Query: 194 DVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTE--PEP 251
           DVF  N+SEA +L+G       +  + A ++ + G + +II  G  G ++ +       P
Sbjct: 170 DVFIVNDSEARLLSG-----DPNLVKTARIIREMGPKTLIIKKGEHGALLFTDNGIFAAP 224

Query: 252 KHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDM 290
              P E +   D TGAGD+F G    +LA   N S  +M
Sbjct: 225 A-FPLESI--YDPTGAGDTFAGGFIGHLARCGNTSEAEM 260


>2VAR-A nrPDB
          Length = 313

 Score = 38.9 bits (89), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 63/279 (22%), Positives = 108/279 (38%), Gaps = 34/279 (12%)

Query: 25  MTDLVSLTSRLPKTGETIHGHKFFIGF-----GGKGANQCVQAARLGAMTSMVCKVGKDS 79
           M D+++L   L +      G   F+ +      G   N C+   R     S++ +VG D 
Sbjct: 1   MVDVIALGEPLIQFNSFNPGPLRFVNYFEKHVAGSELNFCIAVVRNHLSCSLIARVGNDE 60

Query: 80  FGNDYIENLKQNDISTEFTYQTKDAATGTASI----IVNNEGQNIIVIVAGANLLLNTED 135
           FG + IE  +   I T       ++ TG   I     +  + + +      A   L+ ED
Sbjct: 61  FGKNIIEYSRAQGIDTSHIKVDNESFTGIYFIQRGYPIPMKSELVYYRKGSAGSRLSPED 120

Query: 136 LRAAANVISRAKVMVCQLEITPATS-------LEALTMARRSGVKTLFNPAPAIADLDPQ 188
           +    N +  ++ +V    IT A S       ++A  +A+   + T   P    +    +
Sbjct: 121 IN--ENYVRNSR-LVHSTGITLAISDNAKEAVIKAFELAKSRSLDTNIRPKLWSSLEKAK 177

Query: 189 FYTLS-------DVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGC 241
              LS       +V   +  + +IL  +T     D  EA     + G +V++  LG++G 
Sbjct: 178 ETILSILKKYDIEVLITDPDDTKILLDVT-----DPDEAYRKYKELGVKVLLYKLGSKGA 232

Query: 242 VVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGAL-AFYL 279
           +         K     KV   D TGAGD+  G   + YL
Sbjct: 233 IAYKDNVKAFKD--AYKVPVEDPTGAGDAMAGTFVSLYL 269


>3NCA-A nrPDB
          Length = 313

 Score = 38.9 bits (89), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 58/286 (20%), Positives = 111/286 (38%), Gaps = 41/286 (14%)

Query: 16  AAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKV 75
           + ++ VG  + D++SL  + PK    I         GG  +N C   + LGA  + +  +
Sbjct: 19  SQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSM 78

Query: 76  GKDSFGNDYIENLKQNDIS-TEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTE 134
                 +  + + ++  +  ++  +Q+K     +  II N+ G   IV+   +   ++  
Sbjct: 79  APGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSAT 138

Query: 135 DLRAAANVISRAKVMVCQ---LEITPATSLEALTMARRSGVKTLFNPAP-----AIADLD 186
           D           KV + Q   + I    + E + M +R        P       ++    
Sbjct: 139 DFE---------KVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEK 189

Query: 187 P-----QFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVII------- 234
           P     Q +   DV   ++   ++   L   SA +A       +++G  +V         
Sbjct: 190 PREELFQLFGYGDVVFVSK---DVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGAD 246

Query: 235 TLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLA 280
            LG +G ++ S   P P        + VDT GAGD+F  ++ F L+
Sbjct: 247 ALGPDGKLLHSDAFPPP--------RVVDTLGAGDTFNASVIFSLS 284


>3B1N-A nrPDB
          Length = 326

 Score = 37.4 bits (85), Expect = 0.008,   Method: Compositional matrix adjust.
 Identities = 56/276 (20%), Positives = 107/276 (38%), Gaps = 31/276 (11%)

Query: 51  FGGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTAS 110
           FGG   N       LG    M+  +G       Y++ +    +S E+     D  +  A 
Sbjct: 46  FGGCAGNIAYALNLLGGDARMMGTLGAVD-AQPYLDRMDALGLSREYVRVLPDTYSAQAM 104

Query: 111 IIVNNEGQNIIVIVAGANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMAR-- 168
           I  + +   I     GA +       ++  N    AK +  +L I      + +      
Sbjct: 105 ITTDLDNNQITAFHPGAMM-------QSHVNHAGEAKDI--KLAIVGPDGFQGMVQHTEE 155

Query: 169 --RSGVKTLFNPAPAIADLD----PQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAAL 222
             ++GV  +F+P   +   D     +   L+     N+ EA+++   T G + D      
Sbjct: 156 LAQAGVPFIFDPGQGLPLFDGATLRRSIELATYIAVNDYEAKLVCDKT-GWSEDE----- 209

Query: 223 VLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPTEKV-KAVDTTGAGDSFVGALAFYLAY 281
             +    Q +IIT G  G  +  +   E   IP  +  + +D TG GD+F G L + + +
Sbjct: 210 --IASRVQALIITRGEHGATIRHRDGTE--QIPAVRAERVIDPTGCGDAFRGGLLYGIEH 265

Query: 282 YPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPYKKDL 317
             + +    L  ++ + A+ +   G Q+  P + ++
Sbjct: 266 GFDWATAGRL--ASLMGALKIAHQGPQTYAPTRAEI 299


>1YGJ-A nrPDB
          Length = 312

 Score = 37.0 bits (84), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 36/133 (27%), Positives = 54/133 (40%), Gaps = 17/133 (12%)

Query: 168 RRSGVKTLFNPAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKR 227
           +R+G   ++ P   +     +   ++D+   N+ EAE+LTG  + S  +A E   +L   
Sbjct: 119 QRNGEGAMYVPDDLLPVYREKVVPVADIITPNQFEAELLTGRKIHSQEEALEVMDMLHSM 178

Query: 228 GCQVVIIT----LGAEGCVVL----SQTEPEPK--------HIPTEKVKAVDTTGAGDSF 271
           G   V+IT    L   G   L    SQ    P          +   KV AV   G GD F
Sbjct: 179 GPDTVVITSSNLLSPRGSDYLMALGSQRTRAPDGSVVTQRIRMEMHKVDAV-FVGTGDLF 237

Query: 272 VGALAFYLAYYPN 284
              L  +   +PN
Sbjct: 238 AAMLLAWTHKHPN 250


>2F7K-A nrPDB
          Length = 327

 Score = 35.8 bits (81), Expect = 0.029,   Method: Compositional matrix adjust.
 Identities = 38/161 (23%), Positives = 67/161 (41%), Gaps = 20/161 (12%)

Query: 168 RRSGVKTLFNPAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKR 227
           +  G  +++ P   +     +   L+D+   N+ EAE+L+G  + S  +A     +L   
Sbjct: 134 KWDGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSM 193

Query: 228 GCQVVIIT-------LGAEGCVVL-SQTEPEPK--------HIPTEKVKAVDTTGAGDSF 271
           G   V+IT        G+   +VL SQ    P          +   KV AV   G GD F
Sbjct: 194 GPDTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAV-FVGTGDLF 252

Query: 272 VGALAFYLAYYPN---LSLEDMLNRSNFIAAVSVQAAGTQS 309
              L  +   +PN   ++ E  ++  + +   ++Q A  Q+
Sbjct: 253 AAMLLAWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQA 293


>3BF5-A nrPDB
          Length = 306

 Score = 33.5 bits (75), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 36/136 (26%), Positives = 57/136 (41%), Gaps = 24/136 (17%)

Query: 158 ATSLEALTMARRSGVKTLFNPAPAI----ADLDPQFYTLSDVFCCNESEAEILTGLTVGS 213
           +T    L MA+    K +F+P+  I     D   +F+ +S +   N+ E  +   +T  S
Sbjct: 147 STGPNYLDMAKSIRSKIIFDPSQEIHKYSKDELKKFHEISYMSIFNDHEYRVFREMTGLS 206

Query: 214 AADAGEAALVLLKRGCQVVIITLGAEGC-VVLSQTEPEPKHIPTEKVKAVDTTGAGDSFV 272
           +                  I+T G  G  + +   + +   IP+    + DT GAGDSF 
Sbjct: 207 SPKV-------------TTIVTNGERGSSLFMDGKKYDFPAIPS----SGDTVGAGDSFR 249

Query: 273 GALAFYLAYYPNLSLE 288
             L  YLA Y   S+E
Sbjct: 250 AGL--YLALYNRRSIE 263


>2AFB-A nrPDB
          Length = 351

 Score = 32.7 bits (73), Expect = 0.23,   Method: Compositional matrix adjust.
 Identities = 71/318 (22%), Positives = 111/318 (34%), Gaps = 47/318 (14%)

Query: 18  VVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGK 77
           VV  G  M  L       P          F + +GG  AN     A++G     V K+  
Sbjct: 15  VVTFGEIMLRLSP-----PDHKRIFQTDSFDVTYGGAEANVAAFLAQMGLDAYFVTKLPN 69

Query: 78  DSFGNDYIENLKQNDISTEFT---------YQTKDAATGTASIIVNNEGQNIIVIVAGAN 128
           +  G+    +L++  + T++          Y  +  A+   S +V +   + I      +
Sbjct: 70  NPLGDAAAGHLRKFGVKTDYIARGGNRIGIYFLEIGASQRPSKVVYDRAHSAISEAKRED 129

Query: 129 LLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKT---------LFNPA 179
              + E +   A     + +     +  P    +AL +A   GV           L+   
Sbjct: 130 F--DWEKILDGARWFHFSGITPPLGKELPLILEDALKVANEKGVTVSCDLNYRARLWTKE 187

Query: 180 PAIADLDPQFYTLSDVFCCNESEAEILTGLTV----------GSAADAGEAALVLLKRGC 229
            A   + P F    DV   NE + E + G++V             A A  A  V  K   
Sbjct: 188 EAQKVMIP-FMEYVDVLIANEEDIEKVLGISVEGLDLKTGKLNREAYAKIAEEVTRKYNF 246

Query: 230 QVVIITLG------AEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYP 283
           + V ITL            V+     +P      ++  VD  GAGDSF GAL      Y 
Sbjct: 247 KTVGITLRESISATVNYWSVMVFENGQPHFSNRYEIHIVDRVGAGDSFAGALI-----YG 301

Query: 284 NLSLEDMLNRSNFIAAVS 301
           +L   D   ++ F AA S
Sbjct: 302 SLMGFDSQKKAEFAAAAS 319


>2AWD-A nrPDB
          Length = 323

 Score = 31.6 bits (70), Expect = 0.45,   Method: Compositional matrix adjust.
 Identities = 16/53 (30%), Positives = 30/53 (56%), Gaps = 2/53 (3%)

Query: 228 GCQVVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLA 280
           G + ++I+LG +G +     +     IPT  ++A +  G+GD+ +  LA+ LA
Sbjct: 218 GIEWIVISLGKDGAIAKHHDQFYRVKIPT--IQAKNPVGSGDATIAGLAYGLA 268


>1HKH-A nrPDB
          Length = 279

 Score = 29.6 bits (65), Expect = 1.8,   Method: Compositional matrix adjust.
 Identities = 20/79 (25%), Positives = 34/79 (43%), Gaps = 5/79 (6%)

Query: 205 ILTGLTVGSAADAGEAALVLLKRGCQ-VVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVD 263
           +L G ++G+    GE A  + + G + V  +   A     L Q +  P+ +P E    ++
Sbjct: 93  VLVGFSMGT----GELARYVARYGHERVAKLAFLASLEPFLVQRDDNPEGVPQEVFDGIE 148

Query: 264 TTGAGDSFVGALAFYLAYY 282
               GD F     FY  +Y
Sbjct: 149 AAAKGDRFAWFTDFYKNFY 167


>4GM6-A nrPDB
          Length = 351

 Score = 29.3 bits (64), Expect = 2.3,   Method: Compositional matrix adjust.
 Identities = 16/55 (29%), Positives = 26/55 (47%)

Query: 49  IGFGGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKD 103
           I  GG  AN  V  ++LG  T +   V  +  G   +E+L ++ + T F  +  D
Sbjct: 53  IHIGGAEANVAVNLSKLGHPTRIATVVPANPIGKMAVEHLWRHQVDTAFVVEAGD 107


>2AA0-A nrPDB
          Length = 383

 Score = 28.9 bits (63), Expect = 3.5,   Method: Compositional matrix adjust.
 Identities = 12/21 (57%), Positives = 15/21 (71%)

Query: 260 KAVDTTGAGDSFVGALAFYLA 280
           K VDT GAGD+FVG   + L+
Sbjct: 329 KIVDTNGAGDAFVGGFLYALS 349


>3LUF-A nrPDB
          Length = 259

 Score = 28.1 bits (61), Expect = 4.9,   Method: Compositional matrix adjust.
 Identities = 21/48 (43%), Positives = 26/48 (54%), Gaps = 2/48 (4%)

Query: 189 FYTLSDVFCCNESEAEI-LTGLTVGSAADAGEAALVLLKRGCQVVIIT 235
           F TL     C   E  + L  LT+  A  +GEA  VLL+RG  VVI+T
Sbjct: 35  FDTLEGARHCQGDEYVVALVDLTLPDAP-SGEAVKVLLERGLPVVILT 81


>3JUL-A nrPDB
          Length = 320

 Score = 27.7 bits (60), Expect = 6.6,   Method: Compositional matrix adjust.
 Identities = 19/49 (38%), Positives = 29/49 (59%), Gaps = 2/49 (4%)

Query: 232 VIITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLA 280
           ++++LGA+G +  +      + IP  KV+  + TGAGD FVGA    LA
Sbjct: 218 LVVSLGAKGSIC-AHNGKLYQVIPP-KVQERNDTGAGDVFVGAFIAGLA 264


>1OXJ-A nrPDB
          Length = 173

 Score = 27.7 bits (60), Expect = 7.2,   Method: Compositional matrix adjust.
 Identities = 17/71 (23%), Positives = 37/71 (52%)

Query: 125 AGANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIAD 184
           A   L L  + L+  AN+++R +  +   ++  +T++E LT    + +K L +P P   +
Sbjct: 51  ASHKLALCIDKLKERANILNRVEQELLSGQMELSTAVEELTNIVLTPMKPLESPGPPEEN 110

Query: 185 LDPQFYTLSDV 195
           +  +F  + D+
Sbjct: 111 IGLRFLKVIDI 121


Searching..................................................done


Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

5C40-A nrPDB                                                          407   e-114
5ZWY-A nrPDB                                                          302   2e-82
4X8F-A nrPDB                                                          293   6e-80
3RY7-A nrPDB                                                          280   4e-76
1VM7-A nrPDB                                                          277   4e-75
1RK2-A nrPDB                                                          276   1e-74
6ILS-A nrPDB                                                          266   8e-72
1TYY-A nrPDB                                                          226   1e-59
3HJ6-A nrPDB                                                          222   1e-58
2C4E-A nrPDB                                                          220   7e-58
6CW5-A nrPDB                                                          220   9e-58
5EYN-A nrPDB                                                          213   1e-55
3KZH-A nrPDB                                                          207   5e-54
2QCV-A nrPDB                                                          203   1e-52
1WYE-A nrPDB                                                          202   2e-52
3H49-A nrPDB                                                          201   4e-52
5KB6-A nrPDB                                                          198   2e-51
2I6B-A nrPDB                                                          198   3e-51
3GBU-A nrPDB                                                          195   2e-50
3I3Y-A nrPDB                                                          194   6e-50
4DU5-A nrPDB                                                          190   8e-49
1V1S-A nrPDB                                                          187   7e-48
3IQ0-A nrPDB                                                          186   1e-47
3UBO-A nrPDB                                                          185   2e-47
3PL2-A nrPDB                                                          183   1e-46
4N08-A nrPDB                                                          181   4e-46
2RBC-A nrPDB                                                          180   6e-46
4LC4-A nrPDB                                                          179   1e-45
3LHX-A nrPDB                                                          178   2e-45
4WJM-A nrPDB                                                          178   3e-45
3LJS-A nrPDB                                                          172   2e-43
2HW1-A nrPDB                                                          170   7e-43
3LOO-A nrPDB                                                          167   6e-42
3GO6-A nrPDB                                                          163   8e-41
2QHP-A nrPDB                                                          161   3e-40
2NWH-A nrPDB                                                          158   5e-39
3N1C-A nrPDB                                                          148   3e-36
2JG5-A nrPDB                                                          103   1e-22

Sequences not found previously or not previously below threshold:

2VAR-A nrPDB                                                          166   1e-41
3NCA-A nrPDB                                                          159   2e-39
2AA0-A nrPDB                                                          127   5e-30
3UQ9-A nrPDB                                                          116   2e-26
2ABQ-A nrPDB                                                          115   3e-26
3KD6-A nrPDB                                                          114   6e-26
3B1N-A nrPDB                                                          113   1e-25
4E84-A nrPDB                                                          111   6e-25
6C9R-A nrPDB                                                          109   2e-24
4E69-A nrPDB                                                          106   1e-23
2AFB-A nrPDB                                                          106   2e-23
3JUL-A nrPDB                                                          101   6e-22
2AWD-A nrPDB                                                          100   7e-22
4GM6-A nrPDB                                                           97   8e-21
3BF5-A nrPDB                                                           96   2e-20
2Q5R-A nrPDB                                                           88   6e-18
2AJR-A nrPDB                                                           84   7e-17
3KTN-A nrPDB                                                           68   4e-12
5YSQ-A nrPDB                                                           61   7e-10
4S1M-A nrPDB                                                           59   4e-09
1YGJ-A nrPDB                                                           56   3e-08
2F7K-A nrPDB                                                           54   1e-07
2I5B-A nrPDB                                                           54   1e-07
4JJP-A nrPDB                                                           53   2e-07
1TD2-A nrPDB                                                           46   2e-05
2DDM-A nrPDB                                                           46   2e-05
3PZS-A nrPDB                                                           45   4e-05
5TQI-A nrPDB                                                           44   8e-05
5B6A-A nrPDB                                                           44   1e-04
1UB0-A nrPDB                                                           43   2e-04
3ZS7-A nrPDB                                                           42   4e-04
3MBJ-A nrPDB                                                           38   0.006
4XF7-A nrPDB                                                           37   0.008
3HYO-A nrPDB                                                           36   0.017
4YL5-A nrPDB                                                           36   0.027
5MEK-A nrPDB                                                           36   0.034
5ZWB-B nrPDB                                                           35   0.044
4I8O-A nrPDB                                                           32   0.29 
3CGD-A nrPDB                                                           32   0.38 
6CY1-A nrPDB                                                           30   1.2  
1J08-A nrPDB                                                           30   1.6  
1BJ4-A nrPDB                                                           29   3.8  
1OXJ-A nrPDB                                                           28   5.5  
4EVZ-A nrPDB                                                           27   9.5  

>5C40-A nrPDB
          Length = 330

 Score =  407 bits (1045), Expect = e-114,   Method: Composition-based stats.
 Identities = 322/322 (100%), Positives = 322/322 (100%)

Query: 1   MAASGEPQRQWQEEVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCV 60
           MAASGEPQRQWQEEVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCV
Sbjct: 1   MAASGEPQRQWQEEVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCV 60

Query: 61  QAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNI 120
           QAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNI
Sbjct: 61  QAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNI 120

Query: 121 IVIVAGANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAP 180
           IVIVAGANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAP
Sbjct: 121 IVIVAGANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAP 180

Query: 181 AIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEG 240
           AIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEG
Sbjct: 181 AIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEG 240

Query: 241 CVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAV 300
           CVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAV
Sbjct: 241 CVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAV 300

Query: 301 SVQAAGTQSSYPYKKDLPLTLF 322
           SVQAAGTQSSYPYKKDLPLTLF
Sbjct: 301 SVQAAGTQSSYPYKKDLPLTLF 322


>5ZWY-A nrPDB
          Length = 349

 Score =  302 bits (772), Expect = 2e-82,   Method: Composition-based stats.
 Identities = 130/316 (41%), Positives = 179/316 (56%), Gaps = 13/316 (4%)

Query: 13  EEVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMV 72
           E    ++VVGSC  D V     +P+ GET+H   F  GFGGKGANQ V A RLGA  +MV
Sbjct: 33  EYAPDILVVGSCFLDYVGYVDHMPQVGETMHSVSFHKGFGGKGANQAVAAGRLGAKVAMV 92

Query: 73  CKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNE-GQNIIVIVAGANLLL 131
             VG D  G+DYI+ L++N + T + ++T  ++TG A I+V+ +   N IVI   A    
Sbjct: 93  SMVGTDGDGSDYIKELERNGVDTAYMFRTGKSSTGLAMILVDTKSSNNEIVICPNATNHF 152

Query: 132 NTEDLRAAANVISRA-----KVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLD 186
             E LRA  N   R      K ++CQ EI   T+L+ +  A   GV T+FN APA    +
Sbjct: 153 TPELLRAQTNNYERILHTGLKYLICQNEIPLPTTLDTIKEAHSRGVYTVFNSAPAPKPAE 212

Query: 187 PQ----FYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCV 242
            +    F     +FC NE EA ++TG+ V     A  A   L + G + V+ITLGA G  
Sbjct: 213 VEQIKPFLPYVSLFCPNEVEATLITGVKVTDTESAFSAIKALQQLGVRDVVITLGAAG-F 271

Query: 243 VLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSV 302
           VLS+   EP H+  + VKAVDTTGAGD FVG++ ++++     +L +   R+N  AA+SV
Sbjct: 272 VLSENGAEPVHVTGKHVKAVDTTGAGDCFVGSMVYFMSR--GRNLLEACKRANECAAISV 329

Query: 303 QAAGTQSSYPYKKDLP 318
              GTQ SYP+  +LP
Sbjct: 330 TRKGTQLSYPHPSELP 345


>4X8F-A nrPDB
          Length = 309

 Score =  293 bits (750), Expect = 6e-80,   Method: Composition-based stats.
 Identities = 110/308 (35%), Positives = 160/308 (51%), Gaps = 5/308 (1%)

Query: 14  EVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVC 73
            +  +VV+GS   D V      P+ GET+HG  + +  GGKGANQ V AAR+ A    + 
Sbjct: 3   HMNKLVVLGSVNADHVLQVPSFPRPGETLHGRNYQVIPGGKGANQAVAAARMQADVGFIA 62

Query: 74  KVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNT 133
            VG DSFG +  E+ K + I+T       +  TG A I V++ G+N I I A AN  L  
Sbjct: 63  CVGDDSFGINIRESFKLDGINTAGVKLQPNCPTGIAMIQVSDSGENSICISAEANAKLTA 122

Query: 134 EDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDPQFYTLS 193
             +      I  A+ ++ QLE      L+A   A+ +    + NPAPA  +L  +     
Sbjct: 123 AAIEPDLAAIRDARYLLMQLETPLDGILKAAQEAKTAKTNVILNPAPA-RELPDELLKCV 181

Query: 194 DVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKH 253
           D+   NE+EAE+LTG+TV   + A +AA  L  +G ++VIITLG++G  +        + 
Sbjct: 182 DLITPNETEAEVLTGITVYDDSSAQQAADALHCKGIEIVIITLGSKGVWLSQN--GRGQR 239

Query: 254 IPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPY 313
           IP   VKA DTT AGD+F GAL         + LE  +  ++  AA+SV   G Q+S P 
Sbjct: 240 IPGFVVKATDTTAAGDTFNGALV--TGLLQEMPLESAIKFAHAAAAISVTRFGAQTSIPT 297

Query: 314 KKDLPLTL 321
           + ++   L
Sbjct: 298 RAEVEAFL 305


>3RY7-A nrPDB
          Length = 304

 Score =  280 bits (717), Expect = 4e-76,   Method: Composition-based stats.
 Identities = 109/302 (36%), Positives = 167/302 (55%), Gaps = 5/302 (1%)

Query: 17  AVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGG-KGANQCVQAARLGAMTSMVCKV 75
            VV++GS   D      R  + GET+H  +    FGG KGANQ +  AR+ A T+ + K+
Sbjct: 4   KVVILGSTNVDQFLTVERYAQPGETLHVEEAQKAFGGGKGANQAIATARMQADTTFITKI 63

Query: 76  GKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTED 135
           G D   +  +E+ K   I T +  +T +A TG A I VN EGQN I +  GAN+ +  ED
Sbjct: 64  GTDGVADFILEDFKVAHIDTSYIIKTAEAKTGQAFITVNAEGQNTIYVYGGANMTMTPED 123

Query: 136 LRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDPQFYTLSDV 195
           +  A + I  A  +V QLE+     + A  +A+  GV T+ NPAPA A L  +  +L D+
Sbjct: 124 VINAKDAIINADFVVAQLEVPIPAIISAFEIAKAHGVTTVLNPAPAKA-LPNELLSLIDI 182

Query: 196 FCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIP 255
              NE+EAE+L+G+ V +     + A   L  G + V+ITLG +G    ++   + +HI 
Sbjct: 183 IVPNETEAELLSGIKVTNEQSMKDNANYFLSIGIKTVLITLGKQGTYFATKN--QSQHIE 240

Query: 256 TEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPYKK 315
             KV A+DTT AGD+F+GA    L    + +L D ++  N  ++++VQ  G Q+S P  +
Sbjct: 241 AYKVNAIDTTAAGDTFIGAFVSRLNKSQD-NLADAIDFGNKASSLTVQKHGAQASIPLLE 299

Query: 316 DL 317
           ++
Sbjct: 300 EV 301


>1VM7-A nrPDB
          Length = 311

 Score =  277 bits (709), Expect = 4e-75,   Method: Composition-based stats.
 Identities = 106/305 (34%), Positives = 154/305 (50%), Gaps = 14/305 (4%)

Query: 18  VVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAM-TSMVCKVG 76
           + VVGS   D+V       K GET    +  +  GGKGANQ V  A++G      V  +G
Sbjct: 17  ISVVGSSNIDIVLKVDHFTKPGETQKAIEMNVFPGGKGANQAVTVAKIGEKGCRFVTCIG 76

Query: 77  KDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDL 136
            D + +  IEN ++  I+    Y      TG A I V+  GQN I+I  GAN  L  E +
Sbjct: 77  NDDYSDLLIENYEKLGITG---YIRVSLPTGRAFIEVDKTGQNRIIIFPGANAELKKELI 133

Query: 137 RAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDPQFYTLSDVF 196
               N +S + +++ Q EI   T+LE    A+R     +F+PAPA   ++ + +   D  
Sbjct: 134 D--WNTLSESDILLLQNEIPFETTLEC---AKRFNGIVIFDPAPA-QGINEEIFQYLDYL 187

Query: 197 CCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPT 256
             NE E E L+    G      +AA   L+ G + VI+ LG +G +++++ E   KH PT
Sbjct: 188 TPNEKEIEALSKDFFGEFLTVEKAAEKFLELGVKNVIVKLGDKGVLLVNKNEK--KHFPT 245

Query: 257 EKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPYKKD 316
            KVKAVDTT AGD F GA A  L+     + E+ +      AA+SV   G QSS P +++
Sbjct: 246 FKVKAVDTTAAGDVFNGAFAVALS--EGKNPEEAVIFGTAAAAISVTRLGAQSSIPAREE 303

Query: 317 LPLTL 321
           +   L
Sbjct: 304 VEAFL 308


>1RK2-A nrPDB
          Length = 309

 Score =  276 bits (705), Expect = 1e-74,   Method: Composition-based stats.
 Identities = 108/309 (34%), Positives = 164/309 (53%), Gaps = 5/309 (1%)

Query: 13  EEVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMV 72
           +   ++VV+GS   D +      P  GET+ G+ + + FGGKGANQ V A R GA  + +
Sbjct: 2   QNAGSLVVLGSINADHILNLQSFPTPGETVTGNHYQVAFGGKGANQAVAAGRSGANIAFI 61

Query: 73  CKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLN 132
              G DS G    + L  ++I        K  +TG A I VN EG+N+I I AGAN  L+
Sbjct: 62  ACTGDDSIGESVRQQLATDNIDITPVSVIKGESTGVALIFVNGEGENVIGIHAGANAALS 121

Query: 133 TEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDPQFYTL 192
              + A    I+ A  ++ QLE    + + A  +A ++      NPAPA  +L  +   L
Sbjct: 122 PALVEAQRERIANASALLMQLESPLESVMAAAKIAHQNKTIVALNPAPA-RELPDELLAL 180

Query: 193 SDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPK 252
            D+   NE+EAE LTG+ V +  DA +AA VL ++G + V+ITLG+ G    +    E +
Sbjct: 181 VDIITPNETEAEKLTGIRVENDEDAAKAAQVLHEKGIRTVLITLGSRGVW--ASVNGEGQ 238

Query: 253 HIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYP 312
            +P  +V+AVDT  AGD+F GAL    A      L + +  ++  AA++V   G Q S P
Sbjct: 239 RVPGFRVQAVDTIAAGDTFNGAL--ITALLEEKPLPEAIRFAHAAAAIAVTRKGAQPSVP 296

Query: 313 YKKDLPLTL 321
           +++++   L
Sbjct: 297 WREEIDAFL 305


>6ILS-A nrPDB
          Length = 313

 Score =  266 bits (680), Expect = 8e-72,   Method: Composition-based stats.
 Identities = 89/310 (28%), Positives = 143/310 (46%), Gaps = 5/310 (1%)

Query: 15  VAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCK 74
              +VVVGS   D+     RLPK GETI         GGKGANQ    A+L   T  V +
Sbjct: 2   APPLVVVGSANADIYVEIERLPKEGETISAKTGQTLAGGKGANQAACGAKLMYPTYFVGR 61

Query: 75  VGKDSFGNDYIENLKQNDISTEFTYQT--KDAATGTASIIVNNEGQNIIVIVAGANLLLN 132
           +G+D+ G    E L  +       Y     +  TG A +++ ++GQN I+IV GAN+   
Sbjct: 62  LGEDAHGKLIAEALGDDGCGVHLDYVRSVNNEPTGHAVVMLQSDGQNSIIIVGGANMKAW 121

Query: 133 TEDL-RAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDPQFYT 191
            E +      ++  A +++ Q EI  + +++     +++GV  + +       +  +   
Sbjct: 122 PEIMSDDDLEIVRNAGIVLLQREIPDSINIQVAKAVKKAGVPVILDVGGMDTPIPNELLD 181

Query: 192 LSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEP 251
             D+   NE+E   LTG+   +     +A     K G + V++ LG++G  +  Q E   
Sbjct: 182 SIDILSPNETELSRLTGMPTETFEQISQAVAKCHKLGVKQVLVKLGSKGSALFIQGEKPI 241

Query: 252 KHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSY 311
           +       + VDTTGAGD+F  A  F +A     S E+ L  +   A++ VQ  G   S 
Sbjct: 242 QQSIIPAAQVVDTTGAGDTFTAA--FAVAMVEGKSHEECLRFAAAAASLCVQVKGAIPSM 299

Query: 312 PYKKDLPLTL 321
           P +K +   L
Sbjct: 300 PDRKSVLKLL 309


>1TYY-A nrPDB
          Length = 339

 Score =  226 bits (575), Expect = 1e-59,   Method: Composition-based stats.
 Identities = 79/331 (23%), Positives = 129/331 (38%), Gaps = 35/331 (10%)

Query: 7   PQRQWQEEVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLG 66
           P+    + +  V V+G    DLV                 +    GG  AN  V  ARLG
Sbjct: 16  PRGSHMKAMNKVWVIGDASVDLVPEKQN-----------SYLKCPGGASANVGVCVARLG 64

Query: 67  AMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNII--VIV 124
                +  +G D  G    +  + N +   F     D  +    + +  +G+     ++ 
Sbjct: 65  GECGFIGCLGDDDAGRFLRQVFQDNGVDVTFLRLDADLTSAVLIVNLTADGERSFTYLVH 124

Query: 125 AGANLLLNTEDLRAAANVISRAKVMVCQLEITPATS--LEALTMARRSGVKTLFNP---- 178
            GA+  ++ +DL                L   PA    LE     R +G   LF+     
Sbjct: 125 PGADTYVSPQDL-PPFRQYEWFYFSSIGLTDRPAREACLEGARRMREAGGYVLFDVNLRS 183

Query: 179 -APAIADLDPQFY----TLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVI 233
                 D  P+       L+ +   +  E   L+G     A+   +A   L   GC   I
Sbjct: 184 KMWGNTDEIPELIARSAALASICKVSADELCQLSG-----ASHWQDARYYLRDLGCDTTI 238

Query: 234 ITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAY---YPNLSLEDM 290
           I+LGA+G ++++       H P  +V  VDTTGAGD+FVG L F L+    + +  L + 
Sbjct: 239 ISLGADGALLITAEGE--FHFPAPRVDVVDTTGAGDAFVGGLLFTLSRANCWDHALLAEA 296

Query: 291 LNRSNFIAAVSVQAAGTQSSYPYKKDLPLTL 321
           ++ +N   A++V A G  ++ P+   L   L
Sbjct: 297 ISNANACGAMAVTAKGAMTALPFPDQLNTFL 327


>3HJ6-A nrPDB
          Length = 327

 Score =  222 bits (566), Expect = 1e-58,   Method: Composition-based stats.
 Identities = 77/315 (24%), Positives = 129/315 (40%), Gaps = 30/315 (9%)

Query: 17  AVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVG 76
            VV +G  + D++S               ++   FGG  AN  V  +RLG   +++ ++G
Sbjct: 23  DVVSLGEILVDMISTEE----VNSLSQSREYTRHFGGSPANIAVNLSRLGKKVALISRLG 78

Query: 77  KDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDL 136
            D+FGN  ++ LK   I T+   Q K+  T    +  +    + +     A++ L  +D+
Sbjct: 79  ADAFGNYLLDVLKGEQIITDGIQQDKERRTTIVYVSKSTRTPDWLPYRE-ADMYLQEDDI 137

Query: 137 RAAANVISRAKVMVCQLEI-----TPATSLEALTMARRSGVKTLFNP---------APAI 182
                +I R+KV      I        T+++A   AR  G    F+P             
Sbjct: 138 --IFELIKRSKVFHLSTFILSRKPARDTAIKAFNYAREQGKIVCFDPCYRKVLWPEGDDG 195

Query: 183 ADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCV 242
           A +  +  + +D    +  +A  L G                L+ G + VI+TLG EG  
Sbjct: 196 AGVVEEIISRADFVKPSLDDARHLFG-----PDSPENYVKRYLELGVKAVILTLGEEG-- 248

Query: 243 VLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSV 302
           V++    E   IP     AVD TGAGD+F     F        +++  +   N +AA  +
Sbjct: 249 VIASDGEEIIRIPAFSEDAVDVTGAGDAFWS--GFICGLLDGYTVKRSIKLGNGVAAFKI 306

Query: 303 QAAGTQSSYPYKKDL 317
           +  G  S  P K+D+
Sbjct: 307 RGVGALSPVPSKEDI 321


>2C4E-A nrPDB
          Length = 302

 Score =  220 bits (560), Expect = 7e-58,   Method: Composition-based stats.
 Identities = 68/308 (22%), Positives = 115/308 (37%), Gaps = 30/308 (9%)

Query: 14  EVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVC 73
           ++  +  VG    D +    + P+   +I        +GG  AN  V   +LG  + ++ 
Sbjct: 4   KMEKITCVGHTALDYIFNVEKFPEPNTSIQIPSARKYYGGAAANTAVGIKKLGVNSELLS 63

Query: 74  KVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLL--- 130
            VG D   + Y   LK  DI+    Y +++  T  A I  + +   I   + GA      
Sbjct: 64  CVGYDFKNSGYERYLKNLDINISKLYYSEEEETPKAWIFTDKDNNQITFFLWGAAKHYKE 123

Query: 131 LNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDPQFY 190
           LN  +       I+            P  +L+    A  + +   F+P   +     +  
Sbjct: 124 LNPPNFNTEIVHIATGD---------PEFNLKCAKKAYGNNL-VSFDPGQDLPQYSKEML 173

Query: 191 ----TLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQ 246
                 ++    N+ E E  + L      D  E            +I+T G++G V+ ++
Sbjct: 174 LEIIEHTNFLFMNKHEFERASNLLNFEIDDYLE--------RVDALIVTKGSKGSVIYTK 225

Query: 247 TEPEPKHIPTEKV-KAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAA 305
            +     IP  K  K +D TGAGDS+     F  AY     LE         A+  V+A 
Sbjct: 226 DKK--IEIPCIKAGKVIDPTGAGDSYRA--GFLSAYVKGYDLEKCGLIGAATASFVVEAK 281

Query: 306 GTQSSYPY 313
           G Q++ P 
Sbjct: 282 GCQTNLPT 289


>6CW5-A nrPDB
          Length = 332

 Score =  220 bits (559), Expect = 9e-58,   Method: Composition-based stats.
 Identities = 91/317 (28%), Positives = 133/317 (41%), Gaps = 31/317 (9%)

Query: 19  VVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGKD 78
           +V GS   D       + + GETI         GGKGANQ    AR G    +   +G D
Sbjct: 16  LVRGSVNIDEFFHLPHIVRPGETISSTGLTKRAGGKGANQAFAVARAGGQVELDGAIGDD 75

Query: 79  SFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDLRA 138
             G    E L+   + T+     KD  TG A I    +G+N IV+ AGAN  L +     
Sbjct: 76  --GIWVKEMLESAGVGTDKLKIVKDEVTGRAVIQSAADGENSIVLHAGANYYLPSPTPTT 133

Query: 139 AANVISRAKVMVCQLEITPATSLEALTMARRSG--VKTLFNPAPAI--ADLDPQFYTLSD 194
           +    +    ++ Q E+  +++L  LT A +S   + ++FNP+P +  A L    +    
Sbjct: 134 SLATYTH---LLVQNEVPLSSTLAYLTAAGQSSPPLTSVFNPSPMLTPAQLREFPWKHLS 190

Query: 195 VFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQV----------------VIITLGA 238
               NE E   L  L  GS+A+ GEA    L+                     +I TLGA
Sbjct: 191 WLIVNEGELGDLL-LAFGSSANPGEAKEDELQAKASAGILELHENDYFSKNVGIICTLGA 249

Query: 239 EGCVVLSQTEPEPKHIPTEKVK--AVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNF 296
           +G ++  +   E  ++P  K++    DTTGAGD F G   F        SL+D L     
Sbjct: 250 KG-ILCYEPGKEVGYLPAAKLQNPVKDTTGAGDCFAGY--FVAGLMSGKSLQDALKTCLV 306

Query: 297 IAAVSVQAAGTQSSYPY 313
              + V+  G   S P 
Sbjct: 307 ACGICVENEGAMESVPT 323


>5EYN-A nrPDB
          Length = 323

 Score =  213 bits (541), Expect = 1e-55,   Method: Composition-based stats.
 Identities = 67/324 (20%), Positives = 129/324 (39%), Gaps = 40/324 (12%)

Query: 13  EEVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMV 72
           + ++ V + G  + DL+             H   +    GG  AN  V  ARL   ++  
Sbjct: 16  DSMSRVWLTGDAVVDLI--------PDGQQH---YLKCPGGAPANVAVAIARLSGRSAFF 64

Query: 73  CKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQN--IIVIVAGANLL 130
            +VG D FG    + L    +  +  +      T T  + ++  G+     ++   A+  
Sbjct: 65  GRVGNDPFGRFMQQTLTDEQVDCQHLHFDPVHRTSTVVVDLDEHGERSFTFMVKPSADQF 124

Query: 131 LNTEDLRAAANVISRAKVMVCQLEI----TPATSLEALTMARRSGVKTLFNP--APAIAD 184
           L   D+    +      + VC + +    + +++  A+   +  G    F+P     +  
Sbjct: 125 LQLSDI---PSFQKGEWLHVCSIALANQPSRSSTFAAIAQMKEVGGYVSFDPNLREEVWS 181

Query: 185 LDPQF-------YTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLG 237
              +          L+DV   +E E + LTG          E    +      +V++TLG
Sbjct: 182 EPQELQATVMRAVGLADVVKFSEEELQFLTGT-----QSIEEGLQAIADFQIPLVVVTLG 236

Query: 238 AEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPN----LSLEDMLNR 293
           A+G +V +    +   +  + VK +DTTGAGD+FVG L + L+   +     ++ D +  
Sbjct: 237 AKGALVATPNSQQI--VSGKAVKPIDTTGAGDAFVGGLLYRLSVAQDWHNQATILDAVKW 294

Query: 294 SNFIAAVSVQAAGTQSSYPYKKDL 317
           +N   A++    G  ++ P +  L
Sbjct: 295 ANGCGALATTQKGAMTALPNQAAL 318


>3KZH-A nrPDB
          Length = 328

 Score =  207 bits (527), Expect = 5e-54,   Method: Composition-based stats.
 Identities = 67/301 (22%), Positives = 126/301 (41%), Gaps = 17/301 (5%)

Query: 13  EEVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMV 72
            +   ++V G+ + D+   +    +   +  GH   I FGG   N     AR+G  T+ +
Sbjct: 4   RKEPYLLVFGASVVDVFGFSKASYRPYNSTPGH-VKISFGGVCRNIAENMARVGVNTNFM 62

Query: 73  CKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANL-LL 131
             +G D  G   +E+ K+     + +   +  +T T   I++  G+ +  I    ++  +
Sbjct: 63  SILGNDEHGKSIVEHSKKIGYHMDDSMVIEGGSTPTYLAILDENGEMVSAIADMKSIGAM 122

Query: 132 NTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPA-----IADLD 186
           NT+ + +   +   A+  V  L+      +E L    +     + +P  A     +  L 
Sbjct: 123 NTDFIDSKREIFENAEYTV--LDSDNPEIMEYLLKNFKDKTNFILDPVSAEKASWVKHLI 180

Query: 187 PQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQ 246
             F+T       N  EAEIL G  +    D  +A+   L  G + V I+L A+G  +   
Sbjct: 181 KDFHT----IKPNRHEAEILAGFPITDTDDLIKASNYFLGLGIKKVFISLDADG--IFYN 234

Query: 247 TEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAG 306
                  I   +V   + TGAGDSFV  L +   Y   + +ED++  +  ++ +++    
Sbjct: 235 DGVSCGKIKATEVDVKNVTGAGDSFVAGLGY--GYMNKMPIEDIVKFAMTMSNITISHEE 292

Query: 307 T 307
           T
Sbjct: 293 T 293


>2QCV-A nrPDB
          Length = 332

 Score =  203 bits (515), Expect = 1e-52,   Method: Composition-based stats.
 Identities = 69/322 (21%), Positives = 127/322 (39%), Gaps = 28/322 (8%)

Query: 17  AVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVG 76
            ++ +G    DL ++    P   ET+    F    GG  AN  + +++LG     + K+ 
Sbjct: 13  DLIAIGRACIDLNAVEYNRPME-ETM---TFSKYVGGSPANIVIGSSKLGLKAGFIGKIA 68

Query: 77  KDSFGNDYIENLKQNDISTEFTYQTKDAA-TGTAS--IIVNNEGQNIIVIVAGANLLLNT 133
            D  G      ++   + T      ++   TG A   I    E   ++     A+L L+ 
Sbjct: 69  DDQHGRFIESYMRGVGVDTSNLVVDQEGHKTGLAFTEIKSPEECSILMYRQDVADLYLSP 128

Query: 134 EDLRAAANVISRAKVMVCQL-----EITPATSLEALTMARRSGVKTLF--NPAPAIADLD 186
           E++  A   I R+K+++          +    L+A+ +A+R+ VK +F  +  P   +  
Sbjct: 129 EEVNEA--YIRRSKLLLVSGTALSKSPSREAVLKAIRLAKRNDVKVVFELDYRPYSWETP 186

Query: 187 PQ-------FYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAE 239
            +           SD+      E ++L   T     D  E    L K   ++++I  G E
Sbjct: 187 EETAVYYSLVAEQSDIVIGTREEFDVLENRT--EKGDNDETIRYLFKHSPELIVIKHGVE 244

Query: 240 GCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAA 299
           G    ++   E       K K + T GAGDS+  A AF  A      +E  L   +  A+
Sbjct: 245 GSFAYTKAG-EAYRGYAYKTKVLKTFGAGDSY--ASAFLYALISGKGIETALKYGSASAS 301

Query: 300 VSVQAAGTQSSYPYKKDLPLTL 321
           + V    +  + P  +++   +
Sbjct: 302 IVVSKHSSSDAMPSVEEIEALI 323


>1WYE-A nrPDB
          Length = 311

 Score =  202 bits (514), Expect = 2e-52,   Method: Composition-based stats.
 Identities = 66/321 (20%), Positives = 124/321 (38%), Gaps = 29/321 (9%)

Query: 15  VAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCK 74
           +A ++ +G  + +  +L+      G   H   F     G  AN CV   + G    ++ K
Sbjct: 1   MAKLITLGEILIEFNALS-----PGPLRHVSYFEKHVAGSEANYCVAFIKQGNECGIIAK 55

Query: 75  VGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASII----VNNEGQNIIVIVAGANLL 130
           VG D FG + IE L+   +          A TG   I     V  + ++I      A   
Sbjct: 56  VGDDEFGYNAIEWLRGQGVDVSHMKIDPSAPTGIFFIQRHYPVPLKSESIYYRKGSAGSK 115

Query: 131 LNTEDLRA----AANVISRAKVMVCQLEITPATSLEALTMARRSGVKT-----LFNPAPA 181
           L+ ED+      +A+++  + + +           +A  +A      T     L++   A
Sbjct: 116 LSPEDVDEEYVKSADLVHSSGITLAISSTAKEAVYKAFEIASNRSFDTNIRLKLWSAEEA 175

Query: 182 IADLDPQFYT-LSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEG 240
             ++              +  +++I+ G      +D  +AA        +++++ LG +G
Sbjct: 176 KREILKLLSKFHLKFLITDTDDSKIILGE-----SDPDKAAKAFSDY-AEIIVMKLGPKG 229

Query: 241 CVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAV 300
            +V    +    +    +V   D TGAGD+  G   F   YY    +E  L+ +   + +
Sbjct: 230 AIVYYDGKK--YYSSGYQVPVEDVTGAGDALGGT--FLSLYYKGFEMEKALDYAIVASTL 285

Query: 301 SVQAAGTQSSYPYKKDLPLTL 321
           +V   G Q + P  KD+   L
Sbjct: 286 NVMIRGDQENLPTTKDIETFL 306


>3H49-A nrPDB
          Length = 325

 Score =  201 bits (511), Expect = 4e-52,   Method: Composition-based stats.
 Identities = 72/323 (22%), Positives = 135/323 (41%), Gaps = 35/323 (10%)

Query: 17  AVVVVGSCMTDL--------VSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAM 68
            V+ +G+ + D+        +      P         +  +  GG   N+    +RLG  
Sbjct: 7   DVICIGAAIVDIPLQPVSKNIFDVDSYPLE-------RIAMTTGGDAINEATIISRLGHR 59

Query: 69  TSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGAN 128
           T+++ ++GKD+ G   +++ ++ +I  +   Q     T     +V  +G+   V     +
Sbjct: 60  TALMSRIGKDAAGQFILDHCRKENIDIQSLKQDVSIDTSINVGLVTEDGERTFVTNRNGS 119

Query: 129 LL-LNTEDLRAAANVISRAKVM-VCQLEITPATSLEALT-MARRSGVKTLFNPAPAIADL 185
           L  LN +D+  A    S+AK++ +  +  +P    +ALT +  ++  + +   A  I   
Sbjct: 120 LWKLNIDDVDFAR--FSQAKLLSLASIFNSPLLDGKALTEIFTQAKARQMIICADMIKPR 177

Query: 186 DP-------QFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGA 238
                    +  +  D    N +EA++LTG          E A   L  G + V+I  G 
Sbjct: 178 LNETLDDICEALSYVDYLFPNFAEAKLLTGKET-----LDEIADCFLACGVKTVVIKTGK 232

Query: 239 EGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIA 298
           +GC +  + +   K      + A+DT GAGD+F  A  F  A     +L +    +N  A
Sbjct: 233 DGCFI-KRGDMTMKVPAVAGITAIDTIGAGDNF--ASGFIAALLEGKNLRECARFANATA 289

Query: 299 AVSVQAAGTQSSYPYKKDLPLTL 321
           A+SV + G  +    +K +   L
Sbjct: 290 AISVLSVGATTGVKNRKLVEQLL 312


>5KB6-A nrPDB
          Length = 363

 Score =  198 bits (504), Expect = 2e-51,   Method: Composition-based stats.
 Identities = 70/365 (19%), Positives = 136/365 (37%), Gaps = 53/365 (14%)

Query: 1   MAASGEPQ-RQWQEEVAAVVV------VGSCMTDLVSLTSRL------PKTG-------- 39
           MAA+ EP+ ++ + E    +       +G+ + D+ ++  +        K          
Sbjct: 3   MAAADEPKPKKLKVEAPQALSENVLFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDK 62

Query: 40  ------ETIHGHKFFIGFGGKGAN---QCVQAARLGAMTS-MVCKVGKDSFGNDYIENLK 89
                 E +   K     GG   N         +     +     +G D FG        
Sbjct: 63  HKELFDELVKKFKVEYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAA 122

Query: 90  QNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDLRAAANV--ISRAK 147
              +   + Y+  +  TGT +  +    ++++  +A AN     + L    N   + +A+
Sbjct: 123 DAHVDAHY-YEQNEQPTGTCAACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKAR 181

Query: 148 VMVCQ---LEITPATSLEALTMARRSG-VKTLFNPAPAIADLDPQFY----TLSDVFCCN 199
           V       L ++P + L+    A  +  V TL   AP I+    +         D+   N
Sbjct: 182 VYYIAGFFLTVSPESVLKVARYAAENNRVFTLNLSAPFISQFFKEALMDVMPYVDILFGN 241

Query: 200 ESEAEILT---GLTVGSAADAGEAALVLLK---RGCQVVIITLGAEGCVVLSQTEPEPKH 253
           E+EA       G       +  + A  L K   +  + VI T G +  +V ++ +     
Sbjct: 242 ETEAATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFP 301

Query: 254 IPTE-KVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYP 312
           +  + + + +DT GAGD+FVG   F      +  L + +   ++ A+V ++  G   ++P
Sbjct: 302 VLDQNQEEIIDTNGAGDAFVG--GFLSQLVSDKPLTECIRAGHYAASVIIRRTGC--TFP 357

Query: 313 YKKDL 317
            K D 
Sbjct: 358 EKPDF 362


>2I6B-A nrPDB
          Length = 345

 Score =  198 bits (503), Expect = 3e-51,   Method: Composition-based stats.
 Identities = 62/314 (19%), Positives = 120/314 (38%), Gaps = 29/314 (9%)

Query: 27  DLVSLTSRLPKT-GETIHGHKFFIGFGGKGANQCVQAARLGAM-----TSMVCKVGKDSF 80
           D +    +  +   E +   K     GG   N  ++ A+          +    +G D F
Sbjct: 37  DQILAEDKHKELFDELVKKFKVEYHAGGSTQN-SIKVAQWMIQQPHKAATFFGCIGIDKF 95

Query: 81  GNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDLRAAA 140
           G        +  +   + Y+  +  TGT +  +  + +++I  +A AN     + L    
Sbjct: 96  GEILKRKAAEAHVDAHY-YEQNEQPTGTCAACITGDNRSLIANLAAANCYKKEKHLDLEK 154

Query: 141 NVISRAKVMVCQ-----LEITPATSLEALTMARRSGVKTLFN-PAPAIADLDPQ----FY 190
           N +   K  VC      L ++P + L+    A  +      N  AP I+    +      
Sbjct: 155 NWMLVEKARVCYIAGFFLTVSPESVLKVAHHASENNRIFTLNLSAPFISQFYKESLMKVM 214

Query: 191 TLSDVFCCNESEAEILT---GLTVGSAADAGEAALVLLK---RGCQVVIITLGAEGCVVL 244
              D+   NE+EA       G       +  +    L K   +  ++VI T G +  ++ 
Sbjct: 215 PYVDILFGNETEAATFAREQGFETKDIKEIAKKTQALPKMNSKRQRIVIFTQGRDDTIMA 274

Query: 245 SQTEPEPKHIPTEKVK-AVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQ 303
           +++E     +  +  K  +DT GAGD+FVG   F      +  L + +   ++ A++ ++
Sbjct: 275 TESEVTAFAVLDQDQKEIIDTNGAGDAFVG--GFLSQLVSDKPLTECIRAGHYAASIIIR 332

Query: 304 AAGTQSSYPYKKDL 317
             G   ++P K D 
Sbjct: 333 RTGC--TFPEKPDF 344


>3GBU-A nrPDB
          Length = 313

 Score =  195 bits (496), Expect = 2e-50,   Method: Composition-based stats.
 Identities = 71/316 (22%), Positives = 126/316 (39%), Gaps = 35/316 (11%)

Query: 15  VAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCK 74
           ++ +  +G  + DL+S+     K         F    GG  AN  V  +RLG  +S++ K
Sbjct: 1   MSLIASIGELLIDLISVEEGDLKDVRL-----FEKHPGGAPANVAVGVSRLGVKSSLISK 55

Query: 75  VGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGA--NLLLN 132
           VG D FG   IE L + ++ T    + +   TG   + +     + ++    A  N+ LN
Sbjct: 56  VGNDPFGEYLIEELSKENVDTRGIVKDEKKHTGIVFVQLKGASPSFLLYDDVAYFNMTLN 115

Query: 133 TEDLRAAANV-ISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNP----------APA 181
             +        I     ++     +  T ++ +   + S +   F+              
Sbjct: 116 DINWDIVEEAKIVNFGSVILARNPSRETVMKVIKKIKGSSLIA-FDVNLRLDLWRGQEEE 174

Query: 182 IADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGC 241
           +  +  +   L+D+   +E E   L    V               +G  +  ITLG +G 
Sbjct: 175 MIKVLEESIKLADIVKASEEEVLYLENQGVE-------------VKGSMLTAITLGPKGF 221

Query: 242 VVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVS 301
            ++         +P+  V  +DTTGAGD+F+ AL   +     L L  +   +N +AA+S
Sbjct: 222 RLIKN--ETVVDVPSYNVNPLDTTGAGDAFMAALLVGILKLKGLDLLKLGKFANLVAALS 279

Query: 302 VQAAGTQSSYPYKKDL 317
            Q  G  S+ P K +L
Sbjct: 280 TQKRGAWST-PRKDEL 294


>3I3Y-A nrPDB
          Length = 299

 Score =  194 bits (492), Expect = 6e-50,   Method: Composition-based stats.
 Identities = 82/306 (26%), Positives = 134/306 (43%), Gaps = 24/306 (7%)

Query: 17  AVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVG 76
            V V G+   D       +PK G +IHG K     GGKGANQ +  +R G  T ++   G
Sbjct: 4   RVYVTGNITVDETWSIPDIPKKGASIHGVKVSQDIGGKGANQAIILSRCGIETRLIAATG 63

Query: 77  KDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQN-IIVIVAGANLLLNTED 135
            DS G    + +K   +         +  + T+ I+ + +G N II   A A+     E 
Sbjct: 64  NDSNGAWIRQQIKNEPL-MLLPDGHFNQHSDTSIILNSADGDNAIITTTAAADTFSLDEM 122

Query: 136 LRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDPQFYTLSDV 195
           +   A+ ++   +++ Q   +   +      AR  G+ T+FNP+P   D     + L D+
Sbjct: 123 IPHMADAVA-GDILLQQGNFSLDKTRALFQYARSRGMTTVFNPSPVNPDFCH-LWPLIDI 180

Query: 196 FCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIP 255
              NESEAE+L                     G + ++IT GA G  ++   E + +  P
Sbjct: 181 AVVNESEAELLQP------------------YGVKTLVITQGAAGAWLVQ--EGQRQFCP 220

Query: 256 TEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPYKK 315
               +A+DTTGAGD+F+  +               L  ++  AA++V   GT S++P  +
Sbjct: 221 AVPAEALDTTGAGDTFLAVMLASALLRGVAPDALALAHASRAAAITVSRRGTLSAFPGSR 280

Query: 316 DLPLTL 321
           +L   L
Sbjct: 281 ELAALL 286


>4DU5-A nrPDB
          Length = 336

 Score =  190 bits (482), Expect = 8e-49,   Method: Composition-based stats.
 Identities = 71/325 (21%), Positives = 107/325 (32%), Gaps = 31/325 (9%)

Query: 10  QWQEEVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMT 69
           Q       V+  G  M  LV+      + G   H   F     G   N  +  ARLG   
Sbjct: 21  QSMTSALDVITFGEAMMLLVA-----DRPGPLEHAEAFHKRTAGAETNVAIGLARLGLKV 75

Query: 70  SMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTAS---IIVNNEGQNIIVIVAG 126
               ++G DS G   +  +    I            TG      +   ++          
Sbjct: 76  GWASRLGTDSMGRYLLAAMAAEGIDCSHVVCDATQKTGFQFKGKVTDGSDPPVEYHRKGS 135

Query: 127 ANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALT----MARRSGVKTLFNP---- 178
           A   +   D+  A  + +R            AT+L A      + R +G    F+P    
Sbjct: 136 AASHMGVADIDEAWLLSARHLHATGVFPAISATTLPAARKTMDLMRAAGRSVSFDPNLRP 195

Query: 179 -----APAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVI 233
                   + D      T +D       E   LTG T          A    + G ++V+
Sbjct: 196 TLWATPELMRDAINDLATRADWVLPGMEEGRFLTGETTPEG-----VARFYRQLGAKLVV 250

Query: 234 ITLGAEGCVVLSQTEPEPKHIPTEKV-KAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLN 292
           + LGAEG       E     +    V + VDT GAGD F  A+    A    L + + + 
Sbjct: 251 VKLGAEGAYF--DGEAGSGRVAGFPVAEVVDTVGAGDGF--AVGVISALLDGLGVPEAVK 306

Query: 293 RSNFIAAVSVQAAGTQSSYPYKKDL 317
           R  +I A +VQ  G     P + +L
Sbjct: 307 RGAWIGARAVQVLGDSEGLPTRAEL 331


>1V1S-A nrPDB
          Length = 309

 Score =  187 bits (474), Expect = 7e-48,   Method: Composition-based stats.
 Identities = 68/325 (20%), Positives = 108/325 (33%), Gaps = 42/325 (12%)

Query: 15  VAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKF-FIGFGGKGANQCVQAARLGAMTSMVC 73
           +  VV  G  +  LV      P+    + G +   +  GG   N  V  ARLG     V 
Sbjct: 1   MLEVVTAGEPLVALV------PQEPGHLRGKRLLEVYVGGAEVNVAVALARLGVKVGFVG 54

Query: 74  KVGKDSFGNDYIENLKQNDISTEF---------TYQTKDAATGTASIIVNNEGQNIIVIV 124
           +VG+D  G    E L+   +              Y  +    G   +    +G     + 
Sbjct: 55  RVGEDELGAMVEERLRAEGVDLTHFRRAPGFTGLYLREYLPLGQGRVFYYRKGSAGSALA 114

Query: 125 AGANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFN------- 177
            GA       D       +  + +         A SL A+  A+R GV+   +       
Sbjct: 115 PGAF----DPDYLEGVRFLHLSGITPALSPEARAFSLWAMEEAKRRGVRVSLDVNYRQTL 170

Query: 178 -PAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITL 236
                      +     D+   +E EAE+L G               L       V++  
Sbjct: 171 WSPEEARGFLERALPGVDLLFLSEEEAELLFG----------RVEEALRALSAPEVVLKR 220

Query: 237 GAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNF 296
           GA+G       +          V+AVD  GAGD+F     +       L +E+ L  +N 
Sbjct: 221 GAKGAWAF--VDGRRVEGSAFAVEAVDPVGAGDAFAA--GYLAGAVWGLPVEERLRLANL 276

Query: 297 IAAVSVQAAGTQSSYPYKKDLPLTL 321
           + A    + G     PY++DL + L
Sbjct: 277 LGASVAASRGDHEGAPYREDLEVLL 301


>3IQ0-A nrPDB
          Length = 330

 Score =  186 bits (471), Expect = 1e-47,   Method: Composition-based stats.
 Identities = 66/321 (20%), Positives = 115/321 (35%), Gaps = 27/321 (8%)

Query: 15  VAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCK 74
           ++ V  +G  + ++++     P     I    +     G  A    Q  RLG    ++  
Sbjct: 3   LSKVFTIGEILVEIMASKIGQPFDQPGIWNGPY---PSGAPAIFIDQVTRLGVPCGIISC 59

Query: 75  VGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQN--IIVIVAGANLLLN 132
           VG D FG+  I  L  + +           ATG+A +  +N G    I  I   A   L+
Sbjct: 60  VGNDGFGDINIHRLAADGVDIRGISVLPLEATGSAFVTYHNSGDRDFIFNIKNAACGKLS 119

Query: 133 TEDLRA----AANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNP--------AP 180
            + +                 +    +  A   +A+T+ + +G    F+P         P
Sbjct: 120 AQHVDENILKDCTHFHIMGSSLFSFHMVDA-VKKAVTIVKANGGVISFDPNIRKEMLDIP 178

Query: 181 AIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEG 240
            + D       L+D++  +E E  +L+  +         A    L+ G + VI+  G +G
Sbjct: 179 EMRDALHFVLELTDIYMPSEGEVLLLSPHSTPE-----RAIAGFLEEGVKEVIVKRGNQG 233

Query: 241 CVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAV 300
               S  E    H+ +  V+ VD TGAGD F GA                L  +N   A+
Sbjct: 234 ASYYSANEQ--FHVESYPVEEVDPTGAGDCFGGAWIACRQL--GFDAHRALQYANACGAL 289

Query: 301 SVQAAGTQSSYPYKKDLPLTL 321
           +V   G         ++   +
Sbjct: 290 AVTRRGPMEGTSRLMEIETFI 310


>3UBO-A nrPDB
          Length = 354

 Score =  185 bits (469), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 69/323 (21%), Positives = 118/323 (36%), Gaps = 41/323 (12%)

Query: 17  AVVVVGSCMTDLVSLTSR-LPKTGETIHGH-----------------KFFIGFGGKGANQ 58
            V+ +G+ + D+++       +    I G                        GG   N 
Sbjct: 7   DVLTIGNAIVDIIARCDDSFLEENGIIKGAMNLINADRAELLYSRMGPAVEASGGSAGNT 66

Query: 59  CVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQ 118
               A LG   +   KV  D  G  +  +++   +  +         T  + I V  +G+
Sbjct: 67  AAGVASLGGRAAYFGKVADDQLGEIFTHDIRAQGVHFQTKPLDGHPPTARSMIFVTEDGE 126

Query: 119 NIIVIVAGANLLLNTEDLRAAANVISRAKVMVCQLE-ITPATS----LEALTMARRSGVK 173
             +    GA + L  ED+    +V++++KV   +     P  +     EA  +A   G +
Sbjct: 127 RSMNTYLGACVELGPEDVED--DVVAQSKVTYFEGYLWDPPRAKDAIREAARIAHAHGRE 184

Query: 174 TLFNPAPA--IADLDPQFYTL-----SDVFCCNESEAEILTGLTVGSAADAGEAALVLLK 226
           T    + +  +     +F  L      D+   N  EA  L         +  + AL LL 
Sbjct: 185 TAMTLSDSFCVHRYRSEFLELMRSGTVDIVFANRQEALALY------ETEDFDRALELLA 238

Query: 227 RGCQVVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLS 286
           R C++  +TL  EG VV+   E   +   +   + VDTTGAGD +     F   Y    S
Sbjct: 239 RDCKLAAVTLSEEGSVVVRGAE-RVRVGASVLEQVVDTTGAGDLYAA--GFLFGYTSGRS 295

Query: 287 LEDMLNRSNFIAAVSVQAAGTQS 309
           LE+     N  A + +   G + 
Sbjct: 296 LEECSKLGNLAAGIVIGQIGPRP 318


>3PL2-A nrPDB
          Length = 319

 Score =  183 bits (463), Expect = 1e-46,   Method: Composition-based stats.
 Identities = 76/321 (23%), Positives = 126/321 (39%), Gaps = 31/321 (9%)

Query: 17  AVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVG 76
            V+ +G    D+  L S +           F    GG  AN  V AAR G  ++++ +VG
Sbjct: 10  EVLAIGRLGVDIYPLQSGV----GLADVQSFGKYLGGSAANVSVAAARHGHNSALLSRVG 65

Query: 77  KDSFGNDYIENLKQNDISTEF--TYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTE 134
            D FG   +  L++  +  ++  T QT         I   ++          A   LN E
Sbjct: 66  NDPFGEYLLAELERLGVDNQYVATDQTFKTPVTFCEIFPPDDFPLYFYREPKAPD-LNIE 124

Query: 135 DLRAAANVISRAKVMVCQL-----EITPATSLEALTMARRSGVKTLF--NPAPAIADLDP 187
               + + +  A ++   L     E +  T  E LT  R +   T+F  +  P   +   
Sbjct: 125 SADVSLDDVREADILWFTLTGFSEEPSRGTHREILT-TRANRRHTIFDLDYRPMFWESPE 183

Query: 188 Q-------FYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEG 240
           +           S V   N+ E EI  G T     +   A   LL+RG ++ I+  G +G
Sbjct: 184 EATKQAEWALQHSTVAVGNKEECEIAVGET-----EPERAGRALLERGVELAIVKQGPKG 238

Query: 241 CVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAV 300
             V++ T+ E   +P   V  ++  GAGD+F GAL           LE +L  +N   A+
Sbjct: 239 --VMAMTKDETVEVPPFFVDVINGLGAGDAFGGALCH--GLLSEWPLEKVLRFANTAGAL 294

Query: 301 SVQAAGTQSSYPYKKDLPLTL 321
                   ++ P   ++  +L
Sbjct: 295 VASRLECSTAMPTTDEVEASL 315


>4N08-A nrPDB
          Length = 348

 Score =  181 bits (458), Expect = 4e-46,   Method: Composition-based stats.
 Identities = 62/295 (21%), Positives = 111/295 (37%), Gaps = 28/295 (9%)

Query: 45  HKFFIGFGGKGANQC-----VQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTY 99
                  GG G N       +Q A  G   + V  +  D +G    E  +   I     +
Sbjct: 58  PNVRYVPGGSGLNVARVAQWMQQAYKGKFVTYVGCIADDRYGKVLKEAAEHEGIVMAVEH 117

Query: 100 QTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDLRAAA--NVISRAKVMVCQ---LE 154
            TK A +G  ++ +  + + ++  +  AN  L++E +R+ A    +  +++       L 
Sbjct: 118 TTK-AGSGACAVCITGKERTLVADLGAAN-HLSSEHMRSPAVVRAMDESRIFYFSGFTLT 175

Query: 155 ITPATSLEALTMARR-SGVKTLFNPAPAIADLDP----QFYTLSDVFCCNESEAEILTGL 209
           +     L+A   AR   G+  +   AP I         +    +D+   N  EA+    +
Sbjct: 176 VDVNHVLQACRKAREVDGLFMINLSAPFIMQFFSAQLGEVLPYTDIIVANRHEAKEFANM 235

Query: 210 T------VGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPT-EKVKAV 262
                  V   A    + +       +VV+ T   E  V+ ++   E   +P  ++ K +
Sbjct: 236 MKWDTDCVEEIARRAVSEVPYTGTKGRVVVFTRDIESTVLATKDGVETVPVPQLDQDKVI 295

Query: 263 DTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPYKKDL 317
           D  GAGD+F+G   F  AY     L       ++ A   +Q  G   S+P K   
Sbjct: 296 DMNGAGDAFMG--GFLSAYAVGKDLRRCCETGHYTAQEVIQRDGC--SFPEKPSF 346


>2RBC-A nrPDB
          Length = 343

 Score =  180 bits (457), Expect = 6e-46,   Method: Composition-based stats.
 Identities = 69/304 (22%), Positives = 119/304 (39%), Gaps = 11/304 (3%)

Query: 16  AAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKV 75
             V+ VG+ + D +   + +PK    +  ++      G  ++      R+G   S+   V
Sbjct: 30  KHVLCVGAAVLDTLFRVADMPKGEGKVLPYEVLQIAEGMASSAAYAVHRMGGRASLWGAV 89

Query: 76  GKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTED 135
           G D  G   + +L ++ I T        A +  ++II++N G+ +IV      L    + 
Sbjct: 90  GDDETGTRILRDLSESGIDTSGMTVAPGARSALSTIIIDNRGERLIVPFYDHRLH--EKK 147

Query: 136 LRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDPQFYTLSDV 195
                  I+    ++  +   P  +L+ LT+AR  G   + +   A  +        +  
Sbjct: 148 RACTPEDIALFDAVLVDVRW-PELALDVLTVARALGKPAILDGDVAPVETLEGLAPAATH 206

Query: 196 FCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVI-ITLGAEGCVVLSQTEPEPKHI 254
              +E  A  LTGL         +   VL  R  Q  I +T G  GC      +P     
Sbjct: 207 IVFSEPAATRLTGLET-----VKDMLPVLHARYPQTFIAVTAGPAGCWWTEADDPTVHFQ 261

Query: 255 PTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPYK 314
            T +V+AVDT  AGD F G   F LA    +     +  S+  AA+     G +   P +
Sbjct: 262 TTMQVEAVDTLAAGDIFHGT--FALAMAEGMQSRAAVRLSSVAAALKCTVFGGRIGAPTR 319

Query: 315 KDLP 318
           ++  
Sbjct: 320 EETE 323


>4LC4-A nrPDB
          Length = 352

 Score =  179 bits (455), Expect = 1e-45,   Method: Composition-based stats.
 Identities = 70/324 (21%), Positives = 122/324 (37%), Gaps = 43/324 (13%)

Query: 17  AVVVVGSCMTDLVSLTSR----------------LPKTGETIHGH--KFFIGFGGKGANQ 58
            V+ VG+ + D++S  +                   +  E ++          GG   N 
Sbjct: 27  DVLTVGNAIVDIISRCNDQFLIDNQITKAAMNLIDAERAELLYSRMGPALEASGGSAGNT 86

Query: 59  CVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQ 118
               A LG   +    V  D  G+ +  +++   +  +   +     T  + I V  +G+
Sbjct: 87  AAGVANLGGKAAYFGNVAADQLGDIFTHDIRAQGVHYQTKPKGAFPPTARSMIFVTEDGE 146

Query: 119 NIIVIVAGANLLLNTEDLRAAANVISRAKVMVCQLE-ITPATSLEAL----TMARRSGVK 173
             +    GA + L  ED+ A  +V++ AKV   +     P  + EA+     +A + G +
Sbjct: 147 RSMNTYLGACVELGPEDVEA--DVVADAKVTYFEGYLWDPPRAKEAILDCARIAHQHGRE 204

Query: 174 TLFNPAPA--IADLDPQFYTL-----SDVFCCNESEAEILTGLTVGSAADAGEAALVLLK 226
                + +  +     +F  L      D+   N  EA  L         D  E AL  + 
Sbjct: 205 MSMTLSDSFCVDRYRGEFLDLMRSGKVDIVFANRQEALSLY------QTDDFEEALNRIA 258

Query: 227 RGCQVVIITLGAEGCVVLSQTEPEPKHIPTEKV-KAVDTTGAGDSFVGALAFYLAYYPNL 285
             C++  +T+   G V+L   E    ++   ++ + VDTTGAGD F  A  F   Y    
Sbjct: 259 ADCKIAAVTMSENGAVILKGRER--YYVNAIRIREVVDTTGAGDLF--ASGFLYGYTQGR 314

Query: 286 SLEDMLNRSNFIAAVSVQAAGTQS 309
           SLED        A + +Q  G + 
Sbjct: 315 SLEDCGKLGCLAAGIVIQQIGPRP 338


>3LHX-A nrPDB
          Length = 319

 Score =  178 bits (452), Expect = 2e-45,   Method: Composition-based stats.
 Identities = 64/326 (19%), Positives = 106/326 (32%), Gaps = 49/326 (15%)

Query: 16  AAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARL----GAMTSM 71
             + V+G CM +L            +  G     GFGG   N  V  AR           
Sbjct: 5   KKIAVIGECMIEL------------SEKGADVKRGFGGDTLNTSVYIARQVDPAALTVHY 52

Query: 72  VCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIV---AGAN 128
           V  +G DSF    ++     ++ T  T + ++   G   I  ++ G+         A A 
Sbjct: 53  VTALGTDSFSQQMLDAWHGENVDTSLTQRMENRLPGLYYIETDSTGERTFYYWRNEAAAK 112

Query: 129 LLLNTEDLRAAANVISRAKVMVCQL-------EITPATSLEALTMARRSGVKTLFN---- 177
             L +E   A    ++    +             +    L  L   R  G K +F+    
Sbjct: 113 FWLASEQSAAICEELANFDYLYLSGISLAILSPTSREKLLSLLRECRAKGGKVIFDNNYR 172

Query: 178 -----PAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVV 232
                       +  Q    +D+      + + L G          +        G + V
Sbjct: 173 PRLWASKEETQQVYQQMLECTDIAFLTLDDEDALWGQ-----QPVEDVIARTHNAGVKEV 227

Query: 233 IITLGAEGCVVLSQTEPEPKHIPT---EKVKAVDTTGAGDSFVGALAFYLAYYPNLSLED 289
           ++  GA+ C+V S        +P     K K +DTT AGDSF     +        S E+
Sbjct: 228 VVKRGADSCLV-SIAGEALVDVPAVKLPKEKVIDTTAAGDSFSA--GYLAVRLTGGSAEN 284

Query: 290 MLNRSNFIAAVSVQAAGT---QSSYP 312
              R +  A+  +Q  G    + + P
Sbjct: 285 AAKRGHLTASTVIQYRGAIIPREAMP 310


>4WJM-A nrPDB
          Length = 312

 Score =  178 bits (451), Expect = 3e-45,   Method: Composition-based stats.
 Identities = 67/315 (21%), Positives = 111/315 (35%), Gaps = 37/315 (11%)

Query: 18  VVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGF-GGKGANQCVQAARLGAMTSMVCKVG 76
           ++  G  + D++          ET  G   F  F GG   N  +   RLG  T     + 
Sbjct: 8   ILCCGEALIDML--------PRETTGGETAFQPFAGGSVFNTAIALGRLGVPTGFFSGIS 59

Query: 77  KDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDL 136
            D FG+   + L ++++   F   +    T     +V+ + +        A  +L+  D+
Sbjct: 60  SDFFGDVLRDTLARSNVDYSFAAISNRPTTLAFVRLVDGQARYAFYDENTAGRMLSRNDM 119

Query: 137 RAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLD---------- 186
                 IS        L   P  S+    +AR +  + +F      A+L           
Sbjct: 120 PYVDETISAMLFGCISLISEPCGSVYETLLAREAPNRVMFLDPNIRANLITVRKTHLTRM 179

Query: 187 PQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQ 246
            +   L+D+   ++ + +       G      E A   LK G ++V+IT GA G V  + 
Sbjct: 180 KRMIALADIVKLSDEDLDWF-----GEKGSHDEIAAEWLKLGPKLVVITKGAHGAVAYTN 234

Query: 247 TEPEPKHIPTEKVKAVDTTGAGDSFVGALAF-----------YLAYYPNLSLEDMLNRSN 295
                  +P  KV  VDT GAGD+    +              LA      +   +    
Sbjct: 235 H--ATVPVPGVKVDVVDTVGAGDTVNAGILASLHSQGLLTKDALANLSEDQIHSAVALGV 292

Query: 296 FIAAVSVQAAGTQSS 310
             AAV+V  AG    
Sbjct: 293 RAAAVTVSRAGANPP 307


>3LJS-A nrPDB
          Length = 338

 Score =  172 bits (435), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 70/329 (21%), Positives = 126/329 (38%), Gaps = 38/329 (11%)

Query: 16  AAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKV 75
             ++  G  + D+++    L K G       F    GG  AN  V  ARLG     V  +
Sbjct: 5   KTILCFGEALIDMLA--QPLVKKG---MPRAFLQCAGGAPANVAVAVARLGGAVQFVGML 59

Query: 76  GKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIV--AGANLLLNT 133
           G D FG+   ++  +  + T+   +T  A T  A + ++  G+          A+LL   
Sbjct: 60  GSDMFGDFLFDSFAEAGVVTDGIVRTSTAKTALAFVALDAHGERSFSFYRPPAADLLFRV 119

Query: 134 EDLRAAANVISRAKVMVCQLEITP----ATSLEALTMARRSGVKTLFN------PAPAIA 183
           E  + A +         C   +T       + E +  A+ +G    F+        P   
Sbjct: 120 EHFQDA-SFSDALIFHACSNSMTDADIAEVTFEGMRRAQAAGAIVSFDLNFRPMLWPNGE 178

Query: 184 DLDPQFY---TLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEG 240
           +   + +   +L+DV   +  E + L       AADA      L +   Q++++T  A  
Sbjct: 179 NPASRLWKGLSLADVVKLSSEELDYLANTL---AADANAVIQQLWQGRAQLLLVTDAA-- 233

Query: 241 CVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAY------------YPNLSLE 288
             V   T      +PT +V+  D+  AGD+FVG + +  A             +   S+ 
Sbjct: 234 GPVHWYTRTAGGEVPTFRVQVQDSNAAGDAFVGGMLYTFAQQFDDAAALIDFCHDPESIV 293

Query: 289 DMLNRSNFIAAVSVQAAGTQSSYPYKKDL 317
             L  +  + A++V   G  ++ P   ++
Sbjct: 294 STLRFAAAVGALAVTRQGAFTAMPMLSEV 322


>2HW1-A nrPDB
          Length = 298

 Score =  170 bits (431), Expect = 7e-43,   Method: Composition-based stats.
 Identities = 61/306 (19%), Positives = 117/306 (38%), Gaps = 41/306 (13%)

Query: 14  EVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVC 73
           E   ++ VG  + D++SL  + PK    I         GG  +N C   + LGA  + + 
Sbjct: 2   EEKQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMG 61

Query: 74  KVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNT 133
            +      +  +++L++  +   +T      +   A++I+N          +G+  +L  
Sbjct: 62  SMAPGHVADFVLDDLRRYSVDLRYTVFQTTGSVPIATVIINE--------ASGSRTILYY 113

Query: 134 EDLRAAANVISRAKVMVCQ---LEITPATSLEALTMARRSGVKTLFNPAP-----AIADL 185
           +      +     KV + Q   + I    + E + M +R        P       ++   
Sbjct: 114 DRSLPDVSATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVE 173

Query: 186 DP-----QFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVII------ 234
            P     Q +   DV   ++  A+ L      SA +A       +++G  +V        
Sbjct: 174 KPREELFQLFGYGDVVFVSKDVAKHL---GFQSAEEALRGLYGRVRKGAVLVCAWAEEGA 230

Query: 235 -TLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNR 293
             LG +G ++ S   P P        + VDT GAGD+F  ++ F L+     S+++ L  
Sbjct: 231 DALGPDGKLLHSDAFPPP--------RVVDTLGAGDTFNASVIFSLS--QGRSVQEALRF 280

Query: 294 SNFIAA 299
              +A 
Sbjct: 281 GCQVAG 286


>3LOO-A nrPDB
          Length = 365

 Score =  167 bits (423), Expect = 6e-42,   Method: Composition-based stats.
 Identities = 60/302 (19%), Positives = 119/302 (39%), Gaps = 26/302 (8%)

Query: 28  LVSLTSRLPKTGETIHGHKFFIGFGGKGAN---QCVQAARLGAMTSMVCKVGKDSFGNDY 84
           +++    +P   E I  ++     GG   N         +          VG+D +    
Sbjct: 56  ILAEEKHMPMYQELIEKYQAEYIAGGSVQNSLRVAQWILQRPRTAIFFGCVGQDEYARIL 115

Query: 85  IENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDLRAAAN--V 142
            E    N ++ ++  ++  + TGT +++V    +++   +A AN     E LR+  N   
Sbjct: 116 EERATSNGVNVQYQ-RSATSPTGTCAVLVTGTQRSLCANLAAAND-FTPEHLRSDGNRAY 173

Query: 143 ISRAKVMVCQLE---ITPATSLEALTMARRSGVKTLFN-PAPAIADLD----PQFYTLSD 194
           +  A+          ++  ++L     A  +G   + N  AP +         + +   D
Sbjct: 174 LQGAQFFYVSGFFFTVSFESALSVAKEAAATGRMFMMNLSAPFVPQFYKNNLEEIFPYVD 233

Query: 195 VFCCNESEAEILT---GLTVGSAADAGEAALVLLK---RGCQVVIITLGAEGCVVLSQTE 248
           V   NE+EA  L            + G+    L K   +  ++VIIT G++  +++    
Sbjct: 234 VLFGNETEAIALAKEFNYGTEDLREIGKRIAALPKENGKRKRIVIITQGSDPVLLIEAGT 293

Query: 249 PEPKHIPTEKV---KAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAA 305
              +  P +K+   + VDT GAGD+FVG   F      + +++  +    + A   +Q +
Sbjct: 294 DNVREFPVQKLAPEQMVDTNGAGDAFVG--GFLAQLLQSRTVDVCIKCGIWAAREIIQRS 351

Query: 306 GT 307
           G 
Sbjct: 352 GC 353


>2VAR-A nrPDB
          Length = 313

 Score =  166 bits (420), Expect = 1e-41,   Method: Composition-based stats.
 Identities = 59/322 (18%), Positives = 110/322 (34%), Gaps = 29/322 (9%)

Query: 15  VAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCK 74
           +  V+ +G  +    S        G     + F     G   N C+   R     S++ +
Sbjct: 1   MVDVIALGEPLIQFNSF-----NPGPLRFVNYFEKHVAGSELNFCIAVVRNHLSCSLIAR 55

Query: 75  VGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASII----VNNEGQNIIVIVAGANLL 130
           VG D FG + IE  +   I T       ++ TG   I     +  + + +      A   
Sbjct: 56  VGNDEFGKNIIEYSRAQGIDTSHIKVDNESFTGIYFIQRGYPIPMKSELVYYRKGSAGSR 115

Query: 131 LNTEDLRA----AANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNP--APAIAD 184
           L+ ED+       + ++    + +   +      ++A  +A+   + T   P    ++  
Sbjct: 116 LSPEDINENYVRNSRLVHSTGITLAISDNAKEAVIKAFELAKSRSLDTNIRPKLWSSLEK 175

Query: 185 LDPQFYTL-----SDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAE 239
                 ++      +V   +  + +IL         D  EA     + G +V++  LG++
Sbjct: 176 AKETILSILKKYDIEVLITDPDDTKILL-----DVTDPDEAYRKYKELGVKVLLYKLGSK 230

Query: 240 GCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAA 299
           G +         K     KV   D TGAGD+  G   F   Y     +E  L      + 
Sbjct: 231 GAIAYKDNVKAFKD--AYKVPVEDPTGAGDAMAGT--FVSLYLQGKDIEYSLAHGIAAST 286

Query: 300 VSVQAAGTQSSYPYKKDLPLTL 321
           + +   G     P  +D    L
Sbjct: 287 LVITVRGDNELTPTLEDAERFL 308


>3GO6-A nrPDB
          Length = 310

 Score =  163 bits (413), Expect = 8e-41,   Method: Composition-based stats.
 Identities = 85/296 (28%), Positives = 118/296 (39%), Gaps = 31/296 (10%)

Query: 15  VAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCK 74
              V VVGS   DL  +   LP+ GET+         GGKGANQ V AAR GA       
Sbjct: 19  APRVCVVGSVNMDLTFVVDALPRPGETVLAASLTRTPGGKGANQAVAAARAGAQVQFSGA 78

Query: 75  VGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTE 134
            G D        +L+ N +  + T  T    +GTA I+V+   +N +++  GAN  L   
Sbjct: 79  FGDDPAAAQLRAHLRANAVGLDRTV-TVPGPSGTAIIVVDASAENTVLVAPGANAHLTP- 136

Query: 135 DLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLD--PQFYTL 192
                 + ++   V++ QLEI  AT+L A   A+ +    + N +PA  D         +
Sbjct: 137 ----VPSAVANCDVLLTQLEIPVATALAAARAAQSADAVVMVNASPAGQDRSSLQDLAAI 192

Query: 193 SDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPK 252
           +DV   NE EA                             +ITLG  G   +        
Sbjct: 193 ADVVIANEHEANDWPSPPTH-------------------FVITLGVRGARYVGADG--VF 231

Query: 253 HIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLE--DMLNRSNFIAAVSVQAAG 306
            +P   V  VDT GAGD F G LA      P    E    L R+    A++   +G
Sbjct: 232 EVPAPTVTPVDTAGAGDVFAGVLAANWPRNPGSPAERLRALRRACAAGALATLVSG 287


>2QHP-A nrPDB
          Length = 296

 Score =  161 bits (407), Expect = 3e-40,   Method: Composition-based stats.
 Identities = 62/274 (22%), Positives = 109/274 (39%), Gaps = 16/274 (5%)

Query: 49  IGFGGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGT 108
              GG  AN     ++ G  + +V  VG D  G++ +E  K+  +  +   +  D  TGT
Sbjct: 21  KKIGGAPANFAYHVSQFGFDSRVVSAVGNDELGDEIMEVFKEKQLKNQI--ERVDYPTGT 78

Query: 109 ASIIVNNEGQNIIVI---VAGANLLLNTEDLRAAANVISRAKVMVCQ-LEITPATSLEAL 164
             + +++EG     I   VA  N+    E  R A N  +     + Q  E++ AT    L
Sbjct: 79  VQVTLDDEGVPCYEIKEGVAWDNIPFTDELKRLALNTRAVCFGSLAQRNEVSRATINRFL 138

Query: 165 -TMARRSGVKTLFNPAPA----IADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGE 219
            TM    G   +F+          ++  + +   ++   N+ E   ++ +      D  +
Sbjct: 139 DTMPDIDGQLKIFDINLRQDFYTKEVLRESFKRCNILKINDEELVTISRMFGYPGIDLQD 198

Query: 220 AALVLL-KRGCQVVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFY 278
              +LL K   +++I+T G  G  V +      +  P  KV   DT GAGDSF  A    
Sbjct: 199 KCWILLAKYNLKMLILTCGINGSYVFTPGVVSFQETP--KVPVADTVGAGDSFTAAFC-- 254

Query: 279 LAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYP 312
            +     S+ +    +  ++A     +G     P
Sbjct: 255 ASILNGKSVPEAHKLAVEVSAYVCTQSGAMPELP 288


>3NCA-A nrPDB
          Length = 313

 Score =  159 bits (401), Expect = 2e-39,   Method: Composition-based stats.
 Identities = 60/305 (19%), Positives = 111/305 (36%), Gaps = 43/305 (14%)

Query: 16  AAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKV 75
           + ++ VG  + D++SL  + PK    I         GG  +N C   + LGA  + +  +
Sbjct: 19  SQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSM 78

Query: 76  GKDSFGNDYIENLKQNDISTEFTYQTKDAATG-TASIIVNNEGQNIIVIVAGANLLLNTE 134
                 +  + + ++  +            T  +  II N+ G   IV+          +
Sbjct: 79  APGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLH---------D 129

Query: 135 DLRAAANVISRAKVMVCQ---LEITPATSLEALTMARRSGVKTLFNPAP-----AIADLD 186
                 +     KV + Q   + I    + E + M +R        P       ++    
Sbjct: 130 TSLPDVSATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEK 189

Query: 187 P-----QFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVII------- 234
           P     Q +   DV   ++  A+ L      SA +A       +++G  +V         
Sbjct: 190 PREELFQLFGYGDVVFVSKDVAKHL---GFQSAEEALRGLYGRVRKGAVLVCAWAEEGAD 246

Query: 235 TLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRS 294
            LG +G ++ S   P P        + VDT GAGD+F  ++ F L+     S+++ L   
Sbjct: 247 ALGPDGKLLHSDAFPPP--------RVVDTLGAGDTFNASVIFSLS--QGRSVQEALRFG 296

Query: 295 NFIAA 299
             +A 
Sbjct: 297 CQVAG 301


>2NWH-A nrPDB
          Length = 317

 Score =  158 bits (398), Expect = 5e-39,   Method: Composition-based stats.
 Identities = 77/311 (24%), Positives = 126/311 (40%), Gaps = 23/311 (7%)

Query: 14  EVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVC 73
            +  ++V+G    D   +       G +  G       GG G N     +RLG    ++ 
Sbjct: 2   HMKKILVLGGAHIDRRGMIETETAPGASNPGSWMEE-AGGGGFNAARNLSRLGFEVRIIA 60

Query: 74  KVGKDSFGNDYIENLKQNDI-STEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLL-- 130
             G D  G    E  +Q  +  T FT+  +   + TA +  +    N+++ +A  +L   
Sbjct: 61  PRGGDVTGEVVAEAARQAGVEDTPFTFLDRRTPSYTAILERDG---NLVIALADMDLYKL 117

Query: 131 LNTED--LRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTL--FNPAPAIADLD 186
                  +RA    I  +  ++C   + P  +L AL +  R+  K L     +PA A   
Sbjct: 118 FTPRRLKVRAVREAIIASDFLLCDANL-PEDTLTALGLIARACEKPLAAIAISPAKAVKL 176

Query: 187 PQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQ 246
                  D+   NE+EA  LTG T  +  D      +L K G    ++T GA   V  + 
Sbjct: 177 KAALGDIDILFMNEAEARALTGETAENVRDWPN---ILRKAGLSGGVVTRGASEVVAFNG 233

Query: 247 TEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAG 306
           TE    H P  + +  D TGAGD+   A  +  A     ++ + L +    AA++V    
Sbjct: 234 TEKAILHPPLIR-EVKDVTGAGDAM--ASGYLAAIAEGKTIREALRQGAAAAAITV---- 286

Query: 307 TQSSYPYKKDL 317
            QSS+   +DL
Sbjct: 287 -QSSFATSQDL 296


>3N1C-A nrPDB
          Length = 309

 Score =  148 bits (373), Expect = 3e-36,   Method: Composition-based stats.
 Identities = 60/281 (21%), Positives = 108/281 (38%), Gaps = 21/281 (7%)

Query: 38  TGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEF 97
               +         GG G N     A LG   + +   G  + G   +  L   ++    
Sbjct: 24  PEGKLRCTAPVFEPGGGGINVARAIAHLGGSATAIFPAG-GATGEHLVSLLADENVPVA- 81

Query: 98  TYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDLRAAANV---ISRAKVMVCQLE 154
           T + KD       + V   G+    ++ GA   LN ++ R        I    ++V    
Sbjct: 82  TVEAKDWTRQNLHVHVEASGEQYRFVMPGA--ALNEDEFRQLEEQVLEIESGAILVISGS 139

Query: 155 ITPATSLEALTM----ARRSGVKTLFNPAPAIADLDPQFYTLSDV--FCCNESEAEILTG 208
           + P   LE LT     A++ G++ + + +    +       + ++     N+ E   L  
Sbjct: 140 LPPGVKLEKLTQLISAAQKQGIRCIVDSS---GEALSAALAIGNIELVKPNQKELSALVN 196

Query: 209 LTVGSAADAGEAALVLLKRG-CQVVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGA 267
             +    D  +AA  ++  G  + V+++LG +G + +         +    VK+  T GA
Sbjct: 197 RELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGV--DSENCIQVVPPPVKSQSTVGA 254

Query: 268 GDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQ 308
           GDS VGA+   LA   N SLE+M+       + +    GT+
Sbjct: 255 GDSMVGAMTLKLA--ENASLEEMVRFGVAAGSAATLNQGTR 293


>2AA0-A nrPDB
          Length = 383

 Score =  127 bits (320), Expect = 5e-30,   Method: Composition-based stats.
 Identities = 69/349 (19%), Positives = 113/349 (32%), Gaps = 58/349 (16%)

Query: 17  AVVVVGSCMTDLVSLTSR-------LPKTGETIHGHKFFIG------------FGGKGAN 57
            V  +G+ + DLV+           L +   T+   +                 GG   N
Sbjct: 34  RVFAIGNPILDLVAEVPSSFLDEFFLKRGDATLATPEQMRIYSTLDQFNPTSLPGGSALN 93

Query: 58  QCVQAARL---GAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVN 114
                 +L         +  +G D  G    E   +  ++T F       +TG  ++++N
Sbjct: 94  SVRVVQKLLRKPGSAGYMGAIGDDPRGQVLKELCDKEGLATRFMV-APGQSTGVCAVLIN 152

Query: 115 NEGQNIIVIVAGANLLLN-TEDLRAAANVISRAKVMVCQLEITPATSLEALTMARR--SG 171
            + +  +    GA       ED    A+           L  TP  +LE    A    + 
Sbjct: 153 EK-ERTLCTHLGACGSFRLPEDWTTFASGALIFYATAYTLTATPKNALEVAGYAHGIPNA 211

Query: 172 VKTLFNPAPAIADLDPQ----FYTLSDVFCCNESEAEILTGL--------------TVGS 213
           + TL   AP   +L           +++   NE E   L  +                  
Sbjct: 212 IFTLNLSAPFCVELYKDAMQSLLLHTNILFGNEEEFAHLAKVHNLVAAEKTALSTANKEH 271

Query: 214 AADAGEAALVLLKRGC-----QVVIITLGAEGCVVLSQTEPEPKHIPT------EKVKAV 262
           A +    AL LL  G      ++V++T G    +   QT      +           K V
Sbjct: 272 AVEVCTGALRLLTAGQNTSATKLVVMTRGHNPVIAAEQTADGTVVVHEVGVPVVAAEKIV 331

Query: 263 DTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSY 311
           DT GAGD+FVG   F  A     +++  +   N  A   +Q  G   S+
Sbjct: 332 DTNGAGDAFVG--GFLYALSQGKTVKQCIMCGNACAQDVIQHVGFSLSF 378


>3UQ9-A nrPDB
          Length = 372

 Score =  116 bits (289), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 58/302 (19%), Positives = 110/302 (36%), Gaps = 26/302 (8%)

Query: 28  LVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQA---ARLGAMTSMVCKVGKDSFGNDY 84
           +++    +    E     K     GG   N         +   + S V  +G D  G   
Sbjct: 59  VLAEEKHMTIYDEIQKKKKLNYIAGGATLNTVKMIQWIIQKPFVCSYVGCIGADIQGKYI 118

Query: 85  IENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDLRAA--ANV 142
             +    D+ TEF    +   TG  +++V+ +    +V   GA   L+   +      ++
Sbjct: 119 KNDCSALDLVTEFQIAEEPLMTGKVAVLVSEK-LRSMVTYLGAACDLSLAHIEQPHVWSL 177

Query: 143 ISRAKVMVCQLEITP---ATSLEALTMARRSGVKTLFN-PAPAIADLD----PQFYTLSD 194
           + +A+V      +        L+    +  +     FN  AP ++  +     +  + S+
Sbjct: 178 VEKAQVYYIAGFVINTCYEGMLKIAKHSLENEKLFCFNLSAPFLSQFNTKEVDEMISYSN 237

Query: 195 VFCCNESEAE-------ILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQT 247
           +   NESEAE       +L      +A    +      K+  ++VIIT G    +    +
Sbjct: 238 IVFGNESEAEAYGEVHGLLEDTVHATARYIADLPFADGKKRKRLVIITRGKNPLLYTDSS 297

Query: 248 EPEPKHIPTEK---VKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQA 304
           + E      E+    + +DT GAGD+F     F   Y     +   L+ +   AA  +  
Sbjct: 298 DSEIHQFMVEQFKDDQIIDTNGAGDAFAA--GFIADYIRGKPMITSLHAAVKAAAYIICR 355

Query: 305 AG 306
           +G
Sbjct: 356 SG 357


>2ABQ-A nrPDB
          Length = 306

 Score =  115 bits (287), Expect = 3e-26,   Method: Composition-based stats.
 Identities = 57/300 (19%), Positives = 107/300 (35%), Gaps = 25/300 (8%)

Query: 26  TDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYI 85
            D +       + G      +     GGKG N      RLG  T  +  +G    G    
Sbjct: 11  IDYIVQVENF-QQGVVNRSERDRKQPGGKGINVSRVLKRLGHETKALGFLG-GFTGAYVR 68

Query: 86  ENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDLRAAANVI-- 143
             L++ +I   F     D       I V  +G+    +   A L+   E ++A    +  
Sbjct: 69  NALEKEEIGLSFIEVEGDTR-----INVKIKGKQETELNGTAPLIKK-EHVQALLEQLTE 122

Query: 144 -SRAKVMVCQLEIT---PATSLEALT-MARRSGVKTLFNPAPAIADLDPQFYTLSDVFCC 198
             +  V+V    +    P T   ++T +A+  G     + +     L             
Sbjct: 123 LEKGDVLVLAGSVPQAMPQTIYRSMTQIAKERGAFVAVDTS--GEALHEVLAAKPSFIKP 180

Query: 199 NESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPTEK 258
           N  E   L    + S  DA      L+  G + ++++   +G +  S       ++P+ +
Sbjct: 181 NHHELSELVSKPIASIEDAIPHVQRLIGEGIESILVSFAGDGALFASAEGMFHVNVPSGE 240

Query: 259 VKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPYKKDLP 318
           V+  ++ GAGDS V    F  A     SLED +  +    + +  + G    +  ++++ 
Sbjct: 241 VR--NSVGAGDSVVA--GFLAALQEGKSLEDAVPFAVAAGSATAFSDG----FCTREEVE 292


>3KD6-A nrPDB
          Length = 313

 Score =  114 bits (285), Expect = 6e-26,   Method: Composition-based stats.
 Identities = 59/301 (19%), Positives = 111/301 (36%), Gaps = 34/301 (11%)

Query: 17  AVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARL-GAMTSMVCKV 75
           +++V+GS   D +   +   ++  T+         GG      + A+        MV  V
Sbjct: 4   SLLVIGSLAFDDI--ETPFGRSDNTL---------GGSSTYIALSASYFTDEPIRMVGVV 52

Query: 76  GKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNT-- 133
           G D FG ++ + L   +I T      +D  T   +   + +    +      +  LN   
Sbjct: 53  GSD-FGKEHFDLLHAKNIDTRGIQVIEDGKTFRWAGRYHYD----MNTRDTLDTQLNVFA 107

Query: 134 EDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKT---LFNPAPAIADLDPQFY 190
           E           +K  VC   I P   L+ L       +     +        +   +  
Sbjct: 108 EFDPHVPQYYRDSKF-VCLGNIDPELQLKVLDQIDDPKLVVCDTMNFWIEGKPEELKKVL 166

Query: 191 TLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPE 250
              DVF  N+SEA +L+G       +  + A ++ + G + +II  G  G ++ +     
Sbjct: 167 ARVDVFIVNDSEARLLSG-----DPNLVKTARIIREMGPKTLIIKKGEHGALLFTDNG-- 219

Query: 251 PKHIPTEKVKAV-DTTGAGDSFVGALAFYLAY---YPNLSLEDMLNRSNFIAAVSVQAAG 306
               P   ++++ D TGAGD+F G    +LA         +   +   + +A+  V+  G
Sbjct: 220 IFAAPAFPLESIYDPTGAGDTFAGGFIGHLARCGNTSEAEMRKAVLYGSAMASFCVEQFG 279

Query: 307 T 307
            
Sbjct: 280 P 280


>3B1N-A nrPDB
          Length = 326

 Score =  113 bits (283), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 54/318 (16%), Positives = 106/318 (33%), Gaps = 34/318 (10%)

Query: 15  VAAVVVVGSCMTDLVSLTSRLPKT----------GETIHGHKFFIGFGGKGANQCVQAAR 64
           +A ++  GS   D +       +             +         FGG   N       
Sbjct: 1   MATLIC-GSIAYDNIMTFEGRFREHILPDQVHLINLSFLVPTMRREFGGCAGNIAYALNL 59

Query: 65  LGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIV 124
           LG    M+  +G       Y++ +    +S E+     D  +  A I  + +   I    
Sbjct: 60  LGGDARMMGTLGA-VDAQPYLDRMDALGLSREYVRVLPDTYSAQAMITTDLDNNQITAFH 118

Query: 125 AGANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIAD 184
            GA +  +      A ++      +           ++      ++GV  +F+P   +  
Sbjct: 119 PGAMMQSHVNHAGEAKDIK-----LAIVGPDGFQGMVQHTEELAQAGVPFIFDPGQGLPL 173

Query: 185 LD----PQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEG 240
            D     +   L+     N+ EA+++   T  S  +             Q +IIT G  G
Sbjct: 174 FDGATLRRSIELATYIAVNDYEAKLVCDKTGWSEDEIAS--------RVQALIITRGEHG 225

Query: 241 CVVLSQTEPEPKHIPTEKVK-AVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAA 299
             +  +   E   IP  + +  +D TG GD+F G L +                ++ + A
Sbjct: 226 ATIRHRDGTE--QIPAVRAERVIDPTGCGDAFRGGLLY--GIEHGFDWATAGRLASLMGA 281

Query: 300 VSVQAAGTQSSYPYKKDL 317
           + +   G Q+  P + ++
Sbjct: 282 LKIAHQGPQTYAPTRAEI 299


>4E84-A nrPDB
          Length = 352

 Score =  111 bits (276), Expect = 6e-25,   Method: Composition-based stats.
 Identities = 62/316 (19%), Positives = 109/316 (34%), Gaps = 29/316 (9%)

Query: 7   PQRQWQEEVAAVVVVGSCMTDLVS--LTSRL-PK-TGETIHGHKFFIGFGGKGANQCVQA 62
           P  + Q   + V+VVG  M D        R+ P+     +H  +     GG  AN    A
Sbjct: 45  PVPREQLARSRVLVVGDVMLDRYWFGNVDRISPEAPVPVVHVQRQEERLGGA-ANVARNA 103

Query: 63  ARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIV 122
             LG    ++C VG D  G   +E L  + + T    +     T     ++  + Q + V
Sbjct: 104 VTLGGQAGLLCVVGCDEPGERIVELLGSSGV-TPHLERDPALPTTIKLRVLARQQQLLRV 162

Query: 123 IVAGANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEA---------LTMARRSGVK 173
                               ++R  V++ Q ++   +             +  AR +G  
Sbjct: 163 DFEAMPTH------EVLLAGLARFDVLLPQHDVVLMSDYAKGGLTHVTTMIEKARAAGKA 216

Query: 174 TLFNPAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVI 233
            L +P           Y  + +   N +E   + G            A +  +     ++
Sbjct: 217 VLVDPKGDDWAR----YRGASLITPNRAELREVVGQWKSEDDLRARVANLRAELDIDALL 272

Query: 234 ITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNR 293
           +T   EG  + S       H P    +  D +GAGD+ +  +A  L     + L D +  
Sbjct: 273 LTRSEEGMTLFSAGGE--LHAPALAREVFDVSGAGDTVIATVATMLGA--GVPLVDAVVL 328

Query: 294 SNFIAAVSVQAAGTQS 309
           +N  A + V   GT +
Sbjct: 329 ANRAAGIVVGKLGTAT 344


>6C9R-A nrPDB
          Length = 337

 Score =  109 bits (271), Expect = 2e-24,   Method: Composition-based stats.
 Identities = 59/306 (19%), Positives = 101/306 (33%), Gaps = 27/306 (8%)

Query: 18  VVVVGSCMTDLV----------SLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGA 67
           + V GS  TD +           L   L K   +       +  GG   N       LG 
Sbjct: 16  IAVTGSIATDHLMRFPGRFSEQLLPEHLHKVSLSFLVDDLVMHRGGVAGNMAFAIGVLGG 75

Query: 68  MTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGA 127
             ++V   G D    DY + LK   ++ +    ++ A T   +   + +   I     GA
Sbjct: 76  EVALVGAAGADF--ADYRDWLKARGVNCDHVLISETAHTARFTCTTDVDMAQIASFYPGA 133

Query: 128 NLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDP 187
                   L    + I + + +V      P          R+ G+    +P+  +A L  
Sbjct: 134 MSEARNIKLADVVSAIGKPE-LVIIGANDPEAMFLHTEECRKLGLAFAADPSQQLARLSG 192

Query: 188 QFYTL----SDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVV 243
           +        +     N+ E ++L   T  S AD              + + TLG +G  +
Sbjct: 193 EEIRRLVNGAAYLFTNDYEWDLLLSKTGWSEADVMAQ--------IDLRVTTLGPKGVDL 244

Query: 244 LSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQ 303
           +             +    D TG GD+F     F       L LE      + +A + ++
Sbjct: 245 VEPDGTTIHVGVVPETSQTDPTGVGDAFRA--GFLTGRSAGLGLERSAQLGSLVAVLVLE 302

Query: 304 AAGTQS 309
           + GTQ 
Sbjct: 303 STGTQE 308


>4E69-A nrPDB
          Length = 328

 Score =  106 bits (265), Expect = 1e-23,   Method: Composition-based stats.
 Identities = 63/325 (19%), Positives = 103/325 (31%), Gaps = 48/325 (14%)

Query: 13  EEVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTS-- 70
           + +  ++ +G CM +L                  + +GF G   N     ARL   +   
Sbjct: 21  QSMMHILSIGECMAEL----------APADLPGTYRLGFAGDTFNTAWYLARLRPESRIS 70

Query: 71  MVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAG--AN 128
               +G D+        +    I             G   I +  +G+       G  A 
Sbjct: 71  YFSAIGDDALSQQMRAAMSAAGIDGGGLRVIPGRTVGLYLITL-EQGERSFAYWRGQSAA 129

Query: 129 LLL-----NTEDLRAAANVISRAKVMVCQLEI-TPATSLEALTMARRSGVKTLFNPAPAI 182
             L           A A+V+  + + +  L+    AT L AL  AR +G    F+P    
Sbjct: 130 RELAGDADALAAAMARADVVYFSGITLAILDQCGRATLLRALAQARATGRTIAFDP---- 185

Query: 183 ADLDPQFY--------------TLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRG 228
            +L P+ +               +SD+   +  +     G     A      A    + G
Sbjct: 186 -NLRPRLWAGTGEMTETIMQGAAVSDIALPSFEDEAAWFGDAGPDAT-----ADRYARAG 239

Query: 229 CQVVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLE 288
            + V++  G    V   Q     +       + VDTT AGDSF   L    +      LE
Sbjct: 240 VRSVVVKNGPH-AVHFLQDGRRGRVPVPPVAQVVDTTAAGDSFNAGL--LDSVLAGQPLE 296

Query: 289 DMLNRSNFIAAVSVQAAGTQSSYPY 313
             +  +  +A   VQ  G     P 
Sbjct: 297 TAIAAAAALAGQVVQGKGALVEVPS 321


>2AFB-A nrPDB
          Length = 351

 Score =  106 bits (263), Expect = 2e-23,   Method: Composition-based stats.
 Identities = 64/324 (19%), Positives = 105/324 (32%), Gaps = 42/324 (12%)

Query: 17  AVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVG 76
            VV  G  M  L       P          F + +GG  AN     A++G     V K+ 
Sbjct: 14  KVVTFGEIMLRL-----SPPDHKRIFQTDSFDVTYGGAEANVAAFLAQMGLDAYFVTKLP 68

Query: 77  KDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNT--- 133
            +  G+    +L++  + T++  +  +   G   + +    +   V+   A+  ++    
Sbjct: 69  NNPLGDAAAGHLRKFGVKTDYIARGGN-RIGIYFLEIGASQRPSKVVYDRAHSAISEAKR 127

Query: 134 EDLRAAANVISRAKVMVCQLEITP-----ATSLE-ALTMARRSGVKTL--FNPAPAIADL 185
           ED      ++  A+         P        LE AL +A   GV      N    +   
Sbjct: 128 EDFDWEK-ILDGARWFHFSGITPPLGKELPLILEDALKVANEKGVTVSCDLNYRARLWTK 186

Query: 186 DPQ------FYTLSDVFCCNESEAEILTGLTVG----------SAADAGEAALVLLKRGC 229
           +        F    DV   NE + E + G++V             A A  A  V  K   
Sbjct: 187 EEAQKVMIPFMEYVDVLIANEEDIEKVLGISVEGLDLKTGKLNREAYAKIAEEVTRKYNF 246

Query: 230 QVVIITL--GAEGCVVLSQT----EPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYP 283
           + V ITL       V           +P      ++  VD  GAGDSF GAL +      
Sbjct: 247 KTVGITLRESISATVNYWSVMVFENGQPHFSNRYEIHIVDRVGAGDSFAGALIYGSLM-- 304

Query: 284 NLSLEDMLNRSNFIAAVSVQAAGT 307
               +     +   + +     G 
Sbjct: 305 GFDSQKKAEFAAAASCLKHTIPGD 328


>2JG5-A nrPDB
          Length = 306

 Score =  103 bits (256), Expect = 1e-22,   Method: Composition-based stats.
 Identities = 57/281 (20%), Positives = 106/281 (37%), Gaps = 17/281 (6%)

Query: 26  TDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYI 85
            D V  T+   K          +   GGKG N       L   ++ +   G    G   I
Sbjct: 11  IDYVIFTNDF-KIDGLNRATATYKFAGGKGINVSRVLKTLDVESTALGFAG-GFPGKFII 68

Query: 86  ENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNT-EDLRAAANVIS 144
           + L  + I + F    +D             GQ   +   G ++     E L       +
Sbjct: 69  DTLNNSAIQSNFIEVDEDTRINVKL----KTGQETEINAPGPHITSTQFEQLLQQIKNTT 124

Query: 145 RAKVMVCQLEITPATSLEA----LTMARRSGVKTLFNPAPAIADLDPQFYTLSDVFCCNE 200
              +++    +  +   +A      +  ++G K + +    +A+    ++ L      N+
Sbjct: 125 SEDIVIVAGSVPSSIPSDAYAQIAQITAQTGAKLVVDAEKELAESVLPYHPL--FIKPNK 182

Query: 201 SEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPTEKVK 260
            E E++   TV S AD  +   +L+ +G Q VI++LG +G + + +        P  KV 
Sbjct: 183 DELEVMFNTTVNSDADVIKYGRLLVDKGAQSVIVSLGGDGAIYIDKEISIKAVNPQGKV- 241

Query: 261 AVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVS 301
            V+T G+GDS V  +   +A    LS+E    ++      +
Sbjct: 242 -VNTVGSGDSTVAGMVAGIA--SGLSIEKAFQQAVACGTAT 279


>3JUL-A nrPDB
          Length = 320

 Score =  101 bits (250), Expect = 6e-22,   Method: Composition-based stats.
 Identities = 55/295 (18%), Positives = 109/295 (36%), Gaps = 18/295 (6%)

Query: 23  SCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGKDSFGN 82
           +   D +       +  +T    K     GGKG +     ++ G     +   G D+  +
Sbjct: 10  NPAIDRLLFIRGELEKRKTNRVIKTEFDCGGKGLHVSGVLSKFGIKNEALGIAGSDNL-D 68

Query: 83  DYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTED--LRAAA 140
                LK+  I+ +F  +   +      ++ ++   + ++  AG  +    +D  L+  A
Sbjct: 69  KLYAILKEKHINHDFLVEAGTSTRECFVVLSDDTNGSTMIPEAGFTVSQTNKDNLLKQIA 128

Query: 141 NVISRAKVMVCQLEITPATSL----EALTMARRSGVKTLFNPAPAIADLDPQFYTLSDVF 196
             + +  ++V      P  +L    E L   + +G     + +    +L  +     D  
Sbjct: 129 KKVKKEDMVVIAGSPPPHYTLSDFKELLRTVKATGAFLGCDNSGEYLNLAVEMG--VDFI 186

Query: 197 CCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPT 256
             NE E   +      S  +        L      ++++LGA+G +     +     +  
Sbjct: 187 KPNEDEVIAILDEKTNSLEENIRT----LAEKIPYLVVSLGAKGSICAHNGK--LYQVIP 240

Query: 257 EKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSY 311
            KV+  + TGAGD FVGA    LA   N+ + + L  +   +A  V      SS+
Sbjct: 241 PKVQERNDTGAGDVFVGAFIAGLAM--NMPITETLKVATGCSASKVMQQ-DSSSF 292


>2AWD-A nrPDB
          Length = 323

 Score =  100 bits (249), Expect = 7e-22,   Method: Composition-based stats.
 Identities = 56/300 (18%), Positives = 104/300 (34%), Gaps = 25/300 (8%)

Query: 18  VVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGK 77
           V V  +   D+  L   L K        +     GGKG N       LG        +G 
Sbjct: 5   VTVTMNPSIDISYLLDHL-KLDTVNRTSQVTKTPGGKGLNVTRVIHDLGGDVIATGVLG- 62

Query: 78  DSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDLR 137
              G      LK+ +I   FT   ++     A +    EG    ++ AG    ++ E++ 
Sbjct: 63  GFHGAFIANELKKANIPQAFTSIKEETRDSIAILH---EGNQTEILEAG--PTVSPEEIS 117

Query: 138 AAAN----VISRAKVMVCQLE----ITPATSLEALTMARRSGVKTLFNPAPAIADLDPQF 189
                   +I +A+++         +      E +  A    VK L + +        Q 
Sbjct: 118 NFLENFDQLIKQAEIVTISGSLAKGLPSDFYQELVQKAHAQEVKVLLDTSGDSLRQVLQG 177

Query: 190 YTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKR----GCQVVIITLGAEGCVVLS 245
                +   N  E E L G       +   A    L +    G + ++I+LG +G +  +
Sbjct: 178 PWKPYLIKPNLEELEGLLGQDFSE--NPLAAVQTALTKPMFAGIEWIVISLGKDGAI--A 233

Query: 246 QTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAA 305
           +   +   +    ++A +  G+GD+ +  LA+ LA   +    ++L         + Q  
Sbjct: 234 KHHDQFYRVKIPTIQAKNPVGSGDATIAGLAYGLA--KDAPAAELLKWGMAAGMANAQER 291


>4GM6-A nrPDB
          Length = 351

 Score = 97.2 bits (240), Expect = 8e-21,   Method: Composition-based stats.
 Identities = 52/334 (15%), Positives = 108/334 (32%), Gaps = 35/334 (10%)

Query: 5   GEPQRQWQEEVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAAR 64
           G     +Q  +  VV +G  +  L +      +           I  GG  AN  V  ++
Sbjct: 14  GTENLYFQSMMKQVVTIGELLMRLSTQ-----QGIPFSQTTALDIHIGGAEANVAVNLSK 68

Query: 65  LGAMTSMVCKVGKDSFGNDYIENLKQNDISTEF---------TYQTKDAATGTASIIVNN 115
           LG  T +   V  +  G   +E+L ++ + T F         TY  +      A  +V +
Sbjct: 69  LGHPTRIATVVPANPIGKMAVEHLWRHQVDTAFVVEAGDRLGTYYLESGTALKAPSVVYD 128

Query: 116 EGQNIIVIVAGANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTL 175
              +        +  L+   L     V+  + + +          ++ +  A+R+G+K  
Sbjct: 129 RQHSSFARHKSMDWDLSE--LLKGIRVLHVSGITIALSTFWLEMVVKIIREAKRNGIKIS 186

Query: 176 FNP--------APAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSA----ADAGEAALV 223
           F+           A      Q   L D     + +A     ++  +     A   +   +
Sbjct: 187 FDMNYRAKLWELEAAKRAYQQLLPLVDYCSAGQMDAVAFFEISSETTDYYQAMHDKYPNI 246

Query: 224 LLKRGCQVVIITLGA---EGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLA 280
            L    +  +I+      +G +       E +      +  VD  G GD++  A+     
Sbjct: 247 ELFYATKRTVISASHHLLQGHLWTQGECWESEEYAIYPI--VDRVGGGDAYTAAVLH--G 302

Query: 281 YYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPYK 314
                  ++ +  +   A +     G  + +  K
Sbjct: 303 ILSEWRPDETVKFATAAAGLKHSIHGDINPFDEK 336


>3BF5-A nrPDB
          Length = 306

 Score = 96.0 bits (237), Expect = 2e-20,   Method: Composition-based stats.
 Identities = 55/294 (18%), Positives = 102/294 (34%), Gaps = 38/294 (12%)

Query: 13  EEVAAVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMV 72
           + +  +   G    D++     +P+ G +++       FGG   N  + A +      + 
Sbjct: 18  QGMRFLAYFGHLNIDVLISVDSIPREG-SVNVKDLRPRFGGTAGNFAIVAQKFRIPFDLY 76

Query: 73  CKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLN 132
             VG  +   +Y+  ++   I+T    + +D +     I  + + Q   +          
Sbjct: 77  SAVGMKTH-REYLAMIESMGINTGHVEKFEDESGPICYIATDGKKQVSFMHQGAMAAW-- 133

Query: 133 TEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAI----ADLDPQ 188
                 A  +    + +         T    L MA+    K +F+P+  I     D   +
Sbjct: 134 ------APQLADEYEYVHFS------TGPNYLDMAKSIRSKIIFDPSQEIHKYSKDELKK 181

Query: 189 FYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTE 248
           F+ +S +   N+ E  +   +T  S+                  I+T G  G  +    +
Sbjct: 182 FHEISYMSIFNDHEYRVFREMTGLSSPKV-------------TTIVTNGERGSSLFMDGK 228

Query: 249 PEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSV 302
                 P     + DT GAGDSF   L  YLA Y   S+E  +     IA   +
Sbjct: 229 K--YDFPAIP-SSGDTVGAGDSFRAGL--YLALYNRRSIEKGMIYGTIIAHHVI 277


>2Q5R-A nrPDB
          Length = 330

 Score = 87.5 bits (215), Expect = 6e-18,   Method: Composition-based stats.
 Identities = 45/282 (15%), Positives = 96/282 (34%), Gaps = 29/282 (10%)

Query: 43  HGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTK 102
              +     GGKG N     A++G        +G    G    + L  +    +  +   
Sbjct: 47  RVQEVSKTAGGKGLNVTRVLAQVGEPVLASGFIG-GELGQFIAKKL--DHADIKHAFYNI 103

Query: 103 DAATGTASIIVNNEGQNIIV-------IVAGANLLLNTEDLRAAANVISRAKVMVCQLEI 155
              T     I++   Q  I+           A  + + E L      ++          +
Sbjct: 104 KGETRNCIAILHEGQQTEILEQGPEIDNQEAAGFIKHFEQLLEKVEAVA------ISGSL 157

Query: 156 TPATSLEA----LTMARRSGVKTLFNPAPAIADLDPQFYTLSDVFCCNESEAEILTGLTV 211
               + +     +   +  GV  + + + A      +      V   N SE   L    +
Sbjct: 158 PKGLNQDYYAQIIERCQNKGVPVILDCSGATLQTVLENPYKPTVIKPNISELYQLLNQPL 217

Query: 212 GSAADAGEAA--LVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGD 269
             + ++ + A    L + G + +I++LGA+G    ++       +    +  ++  G+GD
Sbjct: 218 DESLESLKQAVSQPLFE-GIEWIIVSLGAQGAF--AKHNHTFYRVNIPTISVLNPVGSGD 274

Query: 270 SFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSY 311
           S V       A   + +  D+L ++N +  ++ Q    Q+ Y
Sbjct: 275 STVA--GITSAILNHENDHDLLKKANTLGMLNAQE--AQTGY 312


>2AJR-A nrPDB
          Length = 331

 Score = 84.4 bits (207), Expect = 7e-17,   Method: Composition-based stats.
 Identities = 53/294 (18%), Positives = 105/294 (35%), Gaps = 36/294 (12%)

Query: 30  SLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENLK 89
              +RL +  +     K  +  GGKG N  +  ++LG  +     VG    G   +E L+
Sbjct: 32  FQVNRLYRINDL---SKTQMSPGGKGINVSIALSKLGVPSVATGFVG-GYMGKILVEELR 87

Query: 90  QNDISTEFTYQTKDAATGTASIIVNNEGQNIIVI-VAGANLL-LNTED-LRAAANVISRA 146
           +        +   +  T     I++ + + I  I   G ++  ++    LR     +S+ 
Sbjct: 88  KISKLITTNFVYVEGETRENIEIIDEKNKTITAINFPGPDVTDMDVNHFLRRYKMTLSKV 147

Query: 147 KVMVCQLEITPATS----LEALTMARRSGVKTLFNPAPAIADLDPQFYTLSDVFCCN-ES 201
             +V    I P  +     E + +AR  GV       P + +   +     +V   +   
Sbjct: 148 DCVVISGSIPPGVNEGICNELVRLARERGVFVFVEQTPRLLERIYEGPEFPNVVKPDLRG 207

Query: 202 EAEILTGLTVGSAADAGEAALVLLKRGCQVVI-------ITLGAEGCVVLSQTEPEPKHI 254
                 G+ + +  D  + A  L ++    V+       I    EG  ++   E      
Sbjct: 208 NHASFLGVDLKTFDDYVKLAEKLAEKSQVSVVSYEVKNDIVATREGVWLIRSKEE----- 262

Query: 255 PTEKVKAVDT---TGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAA 305
                  +DT    GAGD++V  + +Y   +   +  +M     F +A++    
Sbjct: 263 -------IDTSHLLGAGDAYVAGMVYYFIKH-GANFLEMAKFG-FASALAATRR 307


>3KTN-A nrPDB
          Length = 346

 Score = 68.3 bits (165), Expect = 4e-12,   Method: Composition-based stats.
 Identities = 47/327 (14%), Positives = 94/327 (28%), Gaps = 46/327 (14%)

Query: 17  AVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVG 76
            +   G  M          P+        +  + F G G N     A     T+++ K+ 
Sbjct: 4   KIAAFGEVMLRFT-----PPEYLMLEQTEQLRMNFVGTGVNLLANLAHFQLETALITKLP 58

Query: 77  KDSFGNDYIENLKQNDISTEFTYQTKDAATGTAS-----------IIVNNEGQNIIVIVA 125
            +  G      L++  IS ++    K    G+             +   N  Q+   I  
Sbjct: 59  ANRLGEAGKAALRKLGISDQW-VGEKGDHIGSFFAEMGYGIRPTQVTYQNRHQSAFGISE 117

Query: 126 GANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFN-------- 177
             +     E   A  +++    + +   E T   +L     A     K  F+        
Sbjct: 118 AKDYDF--EAFLAEVDMVHICGISLSLTEKTRDAALILAQKAHAYQKKVCFDFNYRPSLN 175

Query: 178 ---PAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKR-----GC 229
               A  +     +     D+   +  +   L G       +       L++R       
Sbjct: 176 TANSALFMRQQYERILPYCDIVFGSRRDLVELLGFIPREDLEGEAQETELIQRFMSQYNL 235

Query: 230 QVVIITLGAEG-------CVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYY 282
           +    T  +           + +Q E   +      +  +D  GAGD++   + +   Y 
Sbjct: 236 EWFAGTTRSHSQNQNYLSGYLYTQNE--YQQSEKRPLLNLDRIGAGDAYAAGILY--GYS 291

Query: 283 PNLSLEDMLNRSNFIAAVSVQAAGTQS 309
            N SLE  +  +     ++    G   
Sbjct: 292 QNWSLEKAVTFATVNGVLAHTIQGDIP 318


>5YSQ-A nrPDB
          Length = 286

 Score = 60.9 bits (146), Expect = 7e-10,   Method: Composition-based stats.
 Identities = 42/296 (14%), Positives = 104/296 (35%), Gaps = 23/296 (7%)

Query: 28  LVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIEN 87
           +++    + K    + G +  I +GG      + ++ LG  T ++ K  ++         
Sbjct: 1   MITFIGHVSKDVNVVDGKR-EIAYGGGVVMGAITSSLLGVKTKVITKCTREDVSKF--SF 57

Query: 88  LKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDLRAAANVISRAK 147
           L+ N +   F    +  +         +  ++ ++  A      +   +   A  I+   
Sbjct: 58  LRDNGVEVVFLKSPRTTSIENRYGSDPDTRESFLISAADPFTESDLAFIEGEAVHINPLW 117

Query: 148 VMVCQLEITPATSLEALTMARRSGVKTLFNPAPAI----ADLDPQFYTLSDVFCCNESEA 203
                 ++ P    + + ++  +           +     ++  ++    D+F  +  EA
Sbjct: 118 YGEFPEDLIPVLRRKVMFLSADAQGFVRVPENEKLVYRDWEMKEKYLKYLDLFKVDSREA 177

Query: 204 EILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQT-EPEPKHIPTEKVKAV 262
           E LTG       D  E+  ++   G ++++ T  A G +V             + + +  
Sbjct: 178 ETLTGTN-----DLRESCRIIRSFGAKIILATH-ASGVIVFDGNFYEASFRSWSLEGR-- 229

Query: 263 DTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPYKKDLP 318
             TG GD+   A       +  +S+E     +  + +V ++  G       ++DL 
Sbjct: 230 --TGRGDTCTAAFLVGF-VFKKMSIEKATKFAAAVTSVKMRHPGPL----RREDLE 278


>4S1M-A nrPDB
          Length = 287

 Score = 58.6 bits (140), Expect = 4e-09,   Method: Composition-based stats.
 Identities = 41/215 (19%), Positives = 75/215 (34%), Gaps = 27/215 (12%)

Query: 107 GTASIIVNNEGQNIIVIVAGANLLLNT----EDLRAAANVISRAKVMVCQLEITPATSLE 162
               +  +        +V G+ +LLN      D     ++    + +V     +     E
Sbjct: 33  SIFVLTTHLANHTGYPVVGGSGVLLNDFISIMDSLEVNHLDKDIEFLVTGYFPSSDLVYE 92

Query: 163 ALTMARR--SGVKTLFNPAP------------AIADLDPQFYTLSDVFCCNESEAEILTG 208
            +   +R     K  F   P             + D   +    +D+   N +E   LTG
Sbjct: 93  TINRVKRIKDNKKVYFLCDPILGDNGKMYTKSEVQDSMKELIKYADIITPNATELSFLTG 152

Query: 209 LTVGSAADAGEAALVLLKRGCQVVIITLGAEG------CVVLSQTEPEPKHIPTEKVKAV 262
           L V S ++A +A  +L ++G  V+++T   EG      C        +   I   +++  
Sbjct: 153 LEVNSVSEAIKACHILHEQGIPVILVTSIKEGNDIILLCSFKDTLNNKNFTIKIPRIEG- 211

Query: 263 DTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFI 297
           D TG GD+              + LE  +NR+   
Sbjct: 212 DFTGVGDTL--TYILLSWIIKGIPLEHAVNRAIST 244


>1YGJ-A nrPDB
          Length = 312

 Score = 55.5 bits (132), Expect = 3e-08,   Method: Composition-based stats.
 Identities = 37/181 (20%), Positives = 66/181 (36%), Gaps = 33/181 (18%)

Query: 168 RRSGVKTLFNPAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKR 227
           +R+G   ++ P   +     +   ++D+   N+ EAE+LTG  + S  +A E   +L   
Sbjct: 119 QRNGEGAMYVPDDLLPVYREKVVPVADIITPNQFEAELLTGRKIHSQEEALEVMDMLHSM 178

Query: 228 GCQVVII---------------------TLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTG 266
           G   V+I                     T   +G VV  +   E   +    V      G
Sbjct: 179 GPDTVVITSSNLLSPRGSDYLMALGSQRTRAPDGSVVTQRIRMEMHKVDAVFV------G 232

Query: 267 AGDSFVGALAFYLAYYPNLS---LEDMLNRSNFIAAVSVQAAGTQSS---YPYKKDLPLT 320
            GD F   L  +   +PN      E  ++  + +   +++ A  +S     P    L L 
Sbjct: 233 TGDLFAAMLLAWTHKHPNNLKVACEKTVSAMHHVLQRTIKCAKAKSGEGVKPSPAQLELR 292

Query: 321 L 321
           +
Sbjct: 293 M 293


>2F7K-A nrPDB
          Length = 327

 Score = 53.6 bits (127), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 37/173 (21%), Positives = 65/173 (37%), Gaps = 21/173 (12%)

Query: 170 SGVKTLFNPAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGC 229
            G  +++ P   +     +   L+D+   N+ EAE+L+G  + S  +A     +L   G 
Sbjct: 136 DGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGP 195

Query: 230 QVVIITL----GAEGCVVLSQTEPEPKHIPTEKV---------KAVDT--TGAGDSFVGA 274
             V+IT       +G   L     + +  P   V         + VD    G GD F   
Sbjct: 196 DTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAM 255

Query: 275 LAFYLAYYPNLS---LEDMLNRSNFIAAVSVQAAGTQSS---YPYKKDLPLTL 321
           L  +   +PN      E  ++  + +   ++Q A  Q+     P    L L +
Sbjct: 256 LLAWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQAGEGVRPSPMQLELRM 308


>2I5B-A nrPDB
          Length = 271

 Score = 53.6 bits (127), Expect = 1e-07,   Method: Composition-based stats.
 Identities = 31/124 (25%), Positives = 50/124 (40%), Gaps = 11/124 (8%)

Query: 178 PAPAIADLDPQFYTLSDVFCCNESEAEILTGL-TVGSAADAGEAALVLLKRGCQVVIITL 236
                  L  Q   L+ V   N  EA  L+G+  + +  D  EAA  +   G Q V+IT 
Sbjct: 120 YPEHAQALREQLAPLATVITPNLFEASQLSGMDELKTVDDMIEAAKKIHALGAQYVVITG 179

Query: 237 GAEGCVVLSQTEPEPKHIPTEKV---KAVD---TTGAGDSFVGALAFYLAYYPNLSLEDM 290
           G  G +   +         T +V   + +D   T GAG +F  A+   LA      +++ 
Sbjct: 180 G--GKLKHEKAVDVLYDGETAEVLESEMIDTPYTHGAGCTFSAAVTAELA--KGAEVKEA 235

Query: 291 LNRS 294
           +  +
Sbjct: 236 IYAA 239


>4JJP-A nrPDB
          Length = 267

 Score = 53.2 bits (126), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 41/236 (17%), Positives = 82/236 (34%), Gaps = 31/236 (13%)

Query: 76  GKDSFGNDYIENLKQNDISTEFTYQTKDAATGTASII-VNNEGQNIIVIVAGANLLLNTE 134
           G DS G           I  +    +     G + I  +  +    +  V   N  +  +
Sbjct: 16  GSDSSG--------GAGIQADLKTFSAIGTYGMSVITAITAQNTKGVFAVEDLNKKIIKK 67

Query: 135 DLRAAANVI--SRAKVMVCQLEITPATSLEALTMARR-SGVKTLFNP------------A 179
            + A    I     K+ +     +P   LE +   ++ +    + +P             
Sbjct: 68  QIEAVFEDIPPRAVKIGMVS---SPEIILEIVENLKKYNPKYLVVDPVMISKSGYYLLKP 124

Query: 180 PAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGA- 238
            A  +L      L+ +   N  EAE +TG+ + +  D       +L+ G + V++  G  
Sbjct: 125 EAKENLIKYLIPLAYIITPNIPEAEEITGIKIHNVDDMKRVGEEILQLGPKFVLMKGGHL 184

Query: 239 EGCVVLSQTEPEPKHIP-TEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNR 293
           +G  V          +  +E++   +T G G +   A+  YLA      + + +N 
Sbjct: 185 DGEAVDILVGKNIFKVYKSERIDKKNTHGTGCTLSSAITSYLAL--GYEITEAVNL 238


>1TD2-A nrPDB
          Length = 287

 Score = 46.3 bits (108), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 34/131 (25%), Positives = 48/131 (36%), Gaps = 15/131 (11%)

Query: 190 YTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCV------V 243
              SD+   N  E EIL    V +  +A  AA  L+ +G Q+V++   A          +
Sbjct: 137 LPASDIIAPNLVELEILCEHAVNNVEEAVLAARELIAQGPQIVLVKHLARAGYSRDRFEM 196

Query: 244 LSQTEPEPKHIPTEKVK--AVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAA-- 299
           L  T  E  HI    V        G GD   G L   L      +L++ L   +  AA  
Sbjct: 197 LLVTADEAWHISRPLVDFGMRQPVGVGDVTSGLLLVKL--LQGATLQEALE--HVTAAVY 252

Query: 300 -VSVQAAGTQS 309
            + V     Q 
Sbjct: 253 EIMVTTKAMQE 263


>2DDM-A nrPDB
          Length = 283

 Score = 46.3 bits (108), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 28/117 (23%), Positives = 40/117 (34%), Gaps = 12/117 (10%)

Query: 185 LDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVL 244
                  L+     N  E EILTG        A  AA  LL    + V++T  A G    
Sbjct: 145 YRQYLLPLAQGITPNIFELEILTGKNCRDLDSAIAAAKSLLSDTLKWVVVT-SASGN--E 201

Query: 245 SQTEPEPKHIPTEKVKAV-------DTTGAGDSFVGALAFYLAYYPNLSLEDMLNRS 294
              E +   +  + V  +       D  G GD F   L          +L D ++R+
Sbjct: 202 ENQEMQVVVVTADSVNVISHSRVKTDLKGTGDLFCAQL--ISGLLKGKALTDAVHRA 256


>3PZS-A nrPDB
          Length = 289

 Score = 45.1 bits (105), Expect = 4e-05,   Method: Composition-based stats.
 Identities = 27/122 (22%), Positives = 43/122 (35%), Gaps = 12/122 (9%)

Query: 187 PQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIIT-LGAEG----- 240
            +    SD+   N  E E L+G  V +   A + A  L  RG +VV++  L   G     
Sbjct: 136 NEALPASDMIAPNLLELEQLSGERVENVEQAVQVARSLCARGPKVVLVKHLSRAGYHADC 195

Query: 241 --CVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIA 298
              ++++  +      P          G GD   G     +       L+  L   +  A
Sbjct: 196 FEMLLVTADDAWHICRPLVDFGKRQPVGVGDLTSG--LLLVNLLKGEPLDKALE--HVTA 251

Query: 299 AV 300
           AV
Sbjct: 252 AV 253


>5TQI-A nrPDB
          Length = 294

 Score = 44.0 bits (102), Expect = 8e-05,   Method: Composition-based stats.
 Identities = 34/182 (18%), Positives = 62/182 (34%), Gaps = 37/182 (20%)

Query: 138 AAANVISRAKVMVCQLEITPATSLEALTMARRS---------------GVKTLFNPAPAI 182
           AA   + R   ++     +PA +   + + R                 G      P P +
Sbjct: 75  AAIGALKRCDAVLSGFAGSPAQARATVEIVRAVKAMNPNAWYFCDPAMGQTGGIRPEPGV 134

Query: 183 AD-LDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITL----- 236
            + +  +   L+D    N +E + L G  + + A+A +A   L+ RG +++++       
Sbjct: 135 EEFIVNEMPALADGMSPNHTELQKLAGRRIETVAEAVDACRTLIARGPKIILVKHLHDRN 194

Query: 237 ---GAEGCVVLSQTE-----PEPKHIPTEKVKAVDTTGA--------GDSFVGALAFYLA 280
                   + +++TE           P   V   D T A        GDS   A    LA
Sbjct: 195 SPADRFNMLAVTETEAWIGQRPLYAFPRHPVGVGDLTSAIFVARRLRGDSVRAAFEHTLA 254

Query: 281 YY 282
             
Sbjct: 255 AV 256


>5B6A-A nrPDB
          Length = 288

 Score = 43.6 bits (101), Expect = 1e-04,   Method: Composition-based stats.
 Identities = 27/159 (16%), Positives = 48/159 (30%), Gaps = 15/159 (9%)

Query: 149 MVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDPQFYTLSDVFCCNESEAEILTG 208
           +V +++     +L           K           L  +   ++D  C N+ E +    
Sbjct: 98  VVARIKQANPRALYLCDPVMGHPEKGCIVAPEVSDFLLEEAAAVADYLCPNQLELDSFCD 157

Query: 209 LTVGSAADAGEAALVLLKRGCQVVIITL----GAEG------CVVLSQTEPEPKHIPTEK 258
               S AD  E A  LL RG + +++      G  G       V   Q     + +    
Sbjct: 158 RQPNSLADCVEMARSLLARGPRAILVKHLNYPGKAGDTFEMLLVAADQAWHLQRPLLAFP 217

Query: 259 VKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFI 297
            + V   G GD  + +  F         L +    +   
Sbjct: 218 RQPV---GVGD--LASGLFLSRLLLGDDLRNAFEFTGAA 251


>1UB0-A nrPDB
          Length = 258

 Score = 42.8 bits (99), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 27/111 (24%), Positives = 43/111 (38%), Gaps = 5/111 (4%)

Query: 189 FYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLG---AEGCVVLS 245
            + L+D+   N  EAE L G  + +  +A EAA  LL  G + V++  G    E  V L 
Sbjct: 127 LFPLADLVTPNRLEAEALLGRPIRTLKEAEEAAKALLALGPKAVLLKGGHLEGEEAVDLL 186

Query: 246 QTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNF 296
            T          +V   +T G G +   + A          L + +  +  
Sbjct: 187 ATRGGVLRFSAPRVHTRNTHGTGCT--LSAAIAALLAKGRPLAEAVAEAKA 235


>3ZS7-A nrPDB
          Length = 300

 Score = 42.1 bits (97), Expect = 4e-04,   Method: Composition-based stats.
 Identities = 18/65 (27%), Positives = 27/65 (41%)

Query: 171 GVKTLFNPAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQ 230
           G   +      + D   +   L+D+   N  EA +L+G+TV   + A  AA      G  
Sbjct: 121 GDDGIMYCKKEVLDAYRELVPLADIVTPNYFEASLLSGVTVNDLSSAILAADWFHNCGVA 180

Query: 231 VVIIT 235
            VII 
Sbjct: 181 HVIIK 185


>3MBJ-A nrPDB
          Length = 291

 Score = 37.8 bits (86), Expect = 0.006,   Method: Composition-based stats.
 Identities = 25/135 (18%), Positives = 44/135 (32%), Gaps = 14/135 (10%)

Query: 170 SGVKTLFNPAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVG---SAADAGEAALVLLK 226
           +G          + ++     T +DV   N +E   L         +  +  E   +L  
Sbjct: 118 NGRLYTNFDMEMVKEMRH-LITKADVITPNLTELFYLLDEPYKADSTDEELKEYLRLLSD 176

Query: 227 RGCQVVIITLGA-------EGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYL 279
           +G QVVIIT                ++       +    + A    G GD+F   +    
Sbjct: 177 KGPQVVIITSVPVHDEPHKTSVYAYNRQGNRYWKVTCPYLPAHYP-GTGDTFTSVITG-- 233

Query: 280 AYYPNLSLEDMLNRS 294
           +     SL   L+R+
Sbjct: 234 SLMQGDSLPMALDRA 248


>4XF7-A nrPDB
          Length = 273

 Score = 37.4 bits (85), Expect = 0.008,   Method: Composition-based stats.
 Identities = 44/290 (15%), Positives = 84/290 (28%), Gaps = 50/290 (17%)

Query: 17  AVVVVGSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVG 76
             +VVG  + D+V              G+K     GG      +  +R      ++    
Sbjct: 2   KCLVVGHVVRDIVKK------------GNKVLERLGGGAYYSALALSRF-CDVEILT--- 45

Query: 77  KDSFGNDYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDL 136
             SF N   E +K+ +   +      +  T      ++   + + ++   + +    +  
Sbjct: 46  --SFSNLPEEWIKELESMAKLQVVPSETTTTYELTYLDGNRRRLKLLERASPIEELPD-- 101

Query: 137 RAAANVISRAKVMVCQLEITPATSLEALTMARRSGVKT---LFNPAPAIADLDPQ---FY 190
                      +     E+ PA    AL       V     + + +P      P    F 
Sbjct: 102 ----GEYDVLLMNPVAREVPPALVTSALKKFPFVAVDIQGFIRSSSPGEIQYQPIDGSFL 157

Query: 191 TLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPE 250
               +   +  E + L G +                    V++++ G E           
Sbjct: 158 KGVKILHADLGEYQYLQGFSPEF---------------VDVLLLSNGPEPGKAFLHGREY 202

Query: 251 PKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAV 300
                   V    +TGAGD F+GA      +Y        L R+    A+
Sbjct: 203 TFEPVHVGVDE--STGAGDVFLGAFT---GFYSQCPFVQALKRAAAFTAL 247


>3HYO-A nrPDB
          Length = 282

 Score = 36.3 bits (82), Expect = 0.017,   Method: Composition-based stats.
 Identities = 32/142 (22%), Positives = 49/142 (34%), Gaps = 18/142 (12%)

Query: 188 QFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVL---LKRGCQVVI--ITLGAE-GC 241
           Q    +DV   N +EA +LTG       D       L   LK G   VI  +    + GC
Sbjct: 130 QLIQQADVILPNTTEAALLTGAPYQVTPDLEVILPALQAQLKTGAHAVITDVQRADQIGC 189

Query: 242 VVLSQTEP----EPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFI 297
             L +         + +P          G GD+    +A  L       L   L R+N  
Sbjct: 190 AWLDEAGHVQYCGARRLPGHY------NGTGDTLAAVIAGLLGR--GYPLAPTLARANQW 241

Query: 298 AAVSVQAAGTQSSYPYKKDLPL 319
             ++V     Q+    ++ + L
Sbjct: 242 LNMAVAETIAQNRTDDRQGVAL 263


>4YL5-A nrPDB
          Length = 263

 Score = 35.9 bits (81), Expect = 0.027,   Method: Composition-based stats.
 Identities = 14/60 (23%), Positives = 24/60 (40%), Gaps = 5/60 (8%)

Query: 188 QFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQT 247
           +   L+ +   N  E   LTG+T     D  +A   L + G + V++  G E      + 
Sbjct: 135 ELIPLATLITPNTVELRALTGVT-----DLDQATQKLFEMGAKAVLVKGGHEDTPDFIKN 189


>5MEK-A nrPDB
          Length = 322

 Score = 35.5 bits (80), Expect = 0.034,   Method: Composition-based stats.
 Identities = 18/101 (17%), Positives = 37/101 (36%), Gaps = 3/101 (2%)

Query: 146 AKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDPQFYTLSDVFCCNESEAEI 205
           +  +VC    T  T L+ALT A  +  +   +  P +     +F    ++      E ++
Sbjct: 59  SDFLVCSYPKTGTTWLKALTFAIANRSRFDDSSNPLLKRNPHEFVPYIEIDFPFFPEVDV 118

Query: 206 LT---GLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVV 243
           L         +          ++K GC++V I    +   +
Sbjct: 119 LKDKGNTLFSTHIPYELLPDSVVKSGCKMVYIWREPKDTFI 159


>5ZWB-B nrPDB
          Length = 296

 Score = 35.1 bits (79), Expect = 0.044,   Method: Composition-based stats.
 Identities = 24/121 (19%), Positives = 36/121 (29%), Gaps = 7/121 (5%)

Query: 179 APAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGA 238
           A             +     N  E E+L+G    +  +A  AA  LL    + V+IT   
Sbjct: 144 AEIPQAYRTHLLPQAQGLTPNVFELEMLSGKPCRTLEEAVAAAQSLLSDTLKWVVITSAP 203

Query: 239 EGCV----VLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRS 294
              +    V   T    +     +V A +  G GD F   L           L      +
Sbjct: 204 GESLETITVAVVTAQVVEVFAHPRV-ATELKGTGDLFCAELV--SGIVQGKKLTTAAKDA 260

Query: 295 N 295
            
Sbjct: 261 A 261


>4I8O-A nrPDB
          Length = 358

 Score = 32.4 bits (72), Expect = 0.29,   Method: Composition-based stats.
 Identities = 12/55 (21%), Positives = 17/55 (30%)

Query: 94  STEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDLRAAANVISRAKV 148
                +        T  I  N +G   I  + GAN  L  E        I+ A+ 
Sbjct: 44  GLRVVFTRPGVNLATVDIFYNGDGSTTIQYLTGANRSLGQELADHLFETINPAEF 98


>3CGD-A nrPDB
          Length = 480

 Score = 32.1 bits (71), Expect = 0.38,   Method: Composition-based stats.
 Identities = 39/204 (19%), Positives = 66/204 (32%), Gaps = 26/204 (12%)

Query: 83  DYIENLKQNDISTEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDLRAAANV 142
            Y E+ K  D+  EF+Y     ATG   ++   EG+++  +     LL    D       
Sbjct: 126 VYAEHTKTKDV-FEFSYDRLLIATGVRPVMPEWEGRDLQGVH----LLKTIPDAERILKT 180

Query: 143 ISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAI------ADLDPQFYTLSDVF 196
           +   KV    +    A  LE        G K                D+    Y  +D  
Sbjct: 181 LETNKVEDVTIIGGGAIGLEMAETFVELGKKVRMIERNDHIGTIYDGDMAEYIYKEAD-- 238

Query: 197 CCNESEAEILTGLTVGSAADAGEAALVLLKRG---CQVVIITLGAE-------GCVVLSQ 246
              +   EILT   V +         V   +G     +V++++G +       G  + + 
Sbjct: 239 ---KHHIEILTNENVKAFKGNERVEAVETDKGTYKADLVLVSVGVKPNTDFLEGTNIRTN 295

Query: 247 TEPEPKHIPTEKVKAVDTTGAGDS 270
            +   +     +    D   AGD 
Sbjct: 296 HKGAIEVNAYMQTNVQDVYAAGDC 319


>6CY1-A nrPDB
          Length = 329

 Score = 30.1 bits (66), Expect = 1.2,   Method: Composition-based stats.
 Identities = 35/181 (19%), Positives = 65/181 (35%), Gaps = 6/181 (3%)

Query: 140 ANVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDPQFYTLSDVFCCN 199
            + +SRA V   +++      LE + +A   GV+T       I +   +     +V   N
Sbjct: 37  FDKVSRAVVGKSKVDDEVLDDLEEVLIASDVGVETTVKIIRRIEERVAR-DKYVNVAELN 95

Query: 200 ESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPTEKV 259
               E ++GL +    +       + K     VI+ +G  G    +          +E +
Sbjct: 96  NILREEISGLLLE---NPHAGTQNIDKTKKPYVIMVVGVNGVGKTTTIGKLAHQFKSEGL 152

Query: 260 KAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAGTQSSYPYKKDLPL 319
           K V   GA D+F  A    L  +       ++ ++      SV     QS+     D+ +
Sbjct: 153 KVV--LGAADTFRAAAVDQLVIWSERVGVPIVKQAMGSDPASVAFDTVQSAVSQDADVVI 210

Query: 320 T 320
            
Sbjct: 211 I 211


>1J08-A nrPDB
          Length = 226

 Score = 29.7 bits (65), Expect = 1.6,   Method: Composition-based stats.
 Identities = 18/111 (16%), Positives = 26/111 (23%), Gaps = 6/111 (5%)

Query: 165 TMARRSGVKTLFNPAPAIADLDPQFYTLSDVFCCNESEAEILTGLTVGSAADAG-----E 219
            + +      + NP   I  +  +     D       E   LT        D       E
Sbjct: 10  RIIKEEFFSKMVNPVKLIVFIGKEHCQYCDQLKQLVQELSELTDKLSYEIVDFDTPEGKE 69

Query: 220 AALVLLKRGCQVVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDS 270
            A            IT   +   V     P            VD +  GD+
Sbjct: 70  LAEKYRIDRAPATTITQDGKDFGVRYFGIPAGHEFAAFLEDIVDVS-KGDT 119


>1BJ4-A nrPDB
          Length = 470

 Score = 28.6 bits (62), Expect = 3.8,   Method: Composition-based stats.
 Identities = 18/132 (13%), Positives = 37/132 (28%), Gaps = 18/132 (13%)

Query: 49  IGFGGKGANQCVQAARLGAMTSMVCKVGKDSFGNDYIENLKQNDISTEFTYQTKDAATGT 108
             + G  AN  V  A +            +  G     +L      T      K   + T
Sbjct: 106 QPYSGSPANFAVYTALV------------EPHGRIMGLDLPDGGHLTHGFMTDKKKISAT 153

Query: 109 ASIIVNNEGQNIIVIVAGANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALT-MA 167
           +        +++   V      +N + L   A +     ++      +       L  +A
Sbjct: 154 SIFF-----ESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIA 208

Query: 168 RRSGVKTLFNPA 179
             +G   + + A
Sbjct: 209 DENGAYLMADMA 220


>1OXJ-A nrPDB
          Length = 173

 Score = 28.2 bits (61), Expect = 5.5,   Method: Composition-based stats.
 Identities = 18/94 (19%), Positives = 45/94 (47%), Gaps = 2/94 (2%)

Query: 106 TGTASIIVNNEGQNIIVIVAGANLLLN--TEDLRAAANVISRAKVMVCQLEITPATSLEA 163
           T    +++  +    + +  GA+  L    + L+  AN+++R +  +   ++  +T++E 
Sbjct: 30  TYEEMLLITEDFLQSVGVTKGASHKLALCIDKLKERANILNRVEQELLSGQMELSTAVEE 89

Query: 164 LTMARRSGVKTLFNPAPAIADLDPQFYTLSDVFC 197
           LT    + +K L +P P   ++  +F  + D+  
Sbjct: 90  LTNIVLTPMKPLESPGPPEENIGLRFLKVIDIVT 123


>4EVZ-A nrPDB
          Length = 258

 Score = 27.4 bits (59), Expect = 9.5,   Method: Composition-based stats.
 Identities = 29/193 (15%), Positives = 62/193 (32%), Gaps = 11/193 (5%)

Query: 113 VNNEGQNIIVIVAGANLLLNTEDLRAAANVISRAKVMVCQLEITPATSLEALTMARRSGV 172
            + EG + +V +         E +       +    +   +     +  +A  + R    
Sbjct: 39  YDEEGADELVFLDITASHEGRETMLEVVERTAEQVFIPLTVGGGIRSVEDASRLLRAGAD 98

Query: 173 KTLFNPA-----PAIADLDPQFYTLSDVFCCNESEA----EILT-GLTVGSAADAGEAAL 222
           K   N A       I +   +F + + V   +        E+ T G    +  DA E A 
Sbjct: 99  KVSINTAAVKNPELITEAAEEFGSQAVVVAIDAKRVGGGWEVFTHGGRKPTGLDAVEWAR 158

Query: 223 VLLKRGC-QVVIITLGAEGCVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLAY 281
            +++ G  ++++ ++  +G       E          V  + + GAG+    A  F L  
Sbjct: 159 KVVELGAGEILLTSMDRDGTKAGYDLELTRAVSEAVSVPVIASGGAGELEHFAEVFELEG 218

Query: 282 YPNLSLEDMLNRS 294
                   + +  
Sbjct: 219 ADAALAASIFHFG 231


  Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
    Posted date:  Jan 3, 2023  9:05 PM
  Number of letters in database: 10,336,785
  Number of sequences in database:  36,641
  
Lambda     K      H
   0.306    0.125    0.304 

Lambda     K      H
   0.267   0.0389    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,895,886
Number of Sequences: 36641
Number of extensions: 343091
Number of successful extensions: 1548
Number of sequences better than 10.0: 84
Number of HSP's better than 10.0 without gapping: 108
Number of HSP's successfully gapped in prelim test: 38
Number of HSP's that attempted gapping in prelim test: 1188
Number of HSP's gapped (non-prelim): 161
length of query: 322
length of database: 10,336,785
effective HSP length: 97
effective length of query: 225
effective length of database: 6,782,608
effective search space: 1526086800
effective search space used: 1526086800
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.1 bits)
S2: 59 (27.4 bits)