BLASTP 2.2.23 [Feb-03-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.


Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= Q9H3H5
         (408 letters)

Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 
           36,641 sequences; 10,336,785 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

6BW5-A nrPDB                                                          825   0.0  
4J72-A nrPDB                                                           45   4e-05
5JNQ-A nrPDB                                                           30   2.1  

>6BW5-A nrPDB
          Length = 417

 Score =  825 bits (2132), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 408/408 (100%), Positives = 408/408 (100%)

Query: 1   MWAFSELPMPLLINLIVSLLGFVATVTLIPAFRGHFIAARLCGQDLNKTSRQQIPESQGV 60
           MWAFSELPMPLLINLIVSLLGFVATVTLIPAFRGHFIAARLCGQDLNKTSRQQIPESQGV
Sbjct: 1   MWAFSELPMPLLINLIVSLLGFVATVTLIPAFRGHFIAARLCGQDLNKTSRQQIPESQGV 60

Query: 61  ISGAVFLIILFCFIPFPFLNCFVKEQCKAFPHHEFVALIGALLAICCMIFLGFADDVLNL 120
           ISGAVFLIILFCFIPFPFLNCFVKEQCKAFPHHEFVALIGALLAICCMIFLGFADDVLNL
Sbjct: 61  ISGAVFLIILFCFIPFPFLNCFVKEQCKAFPHHEFVALIGALLAICCMIFLGFADDVLNL 120

Query: 121 RWRHKLLLPTAASLPLLMVYFTNFGNTTIVVPKPFRPILGLHLDLGILYYVYMGLLAVFC 180
           RWRHKLLLPTAASLPLLMVYFTNFGNTTIVVPKPFRPILGLHLDLGILYYVYMGLLAVFC
Sbjct: 121 RWRHKLLLPTAASLPLLMVYFTNFGNTTIVVPKPFRPILGLHLDLGILYYVYMGLLAVFC 180

Query: 181 TNAINILAGINGLEAGQSLVISASIIVFNLVELEGDCRDDHVFSLYFMIPFFFTTLGLLY 240
           TNAINILAGINGLEAGQSLVISASIIVFNLVELEGDCRDDHVFSLYFMIPFFFTTLGLLY
Sbjct: 181 TNAINILAGINGLEAGQSLVISASIIVFNLVELEGDCRDDHVFSLYFMIPFFFTTLGLLY 240

Query: 241 HNWYPSRVFVGDTFCYFAGMTFAVVGILGHFSKTMLLFFMPQVFNFLYSLPQLLHIIPCP 300
           HNWYPSRVFVGDTFCYFAGMTFAVVGILGHFSKTMLLFFMPQVFNFLYSLPQLLHIIPCP
Sbjct: 241 HNWYPSRVFVGDTFCYFAGMTFAVVGILGHFSKTMLLFFMPQVFNFLYSLPQLLHIIPCP 300

Query: 301 RHRIPRLNIKTGKLEMSYSKFKTKSLSFLGTFILKVAESLQLVTVHQSETEDGEFTECNN 360
           RHRIPRLNIKTGKLEMSYSKFKTKSLSFLGTFILKVAESLQLVTVHQSETEDGEFTECNN
Sbjct: 301 RHRIPRLNIKTGKLEMSYSKFKTKSLSFLGTFILKVAESLQLVTVHQSETEDGEFTECNN 360

Query: 361 MTLINLLLKVLGPIHERNLTLLLLLLQILGSAITFSIRYQLVRLFYDV 408
           MTLINLLLKVLGPIHERNLTLLLLLLQILGSAITFSIRYQLVRLFYDV
Sbjct: 361 MTLINLLLKVLGPIHERNLTLLLLLLQILGSAITFSIRYQLVRLFYDV 408


>4J72-A nrPDB
          Length = 365

 Score = 45.4 bits (106), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 44/179 (24%), Positives = 84/179 (46%), Gaps = 31/179 (17%)

Query: 111 LGFADDVLNLRWRHKLLLPT-------AASLPLLMVYFTNFGNTTIVVPKPFRPILGLHL 163
           +GF DD + L+ +  + + T       +ASL  +++Y+    +T +  P  F+    L++
Sbjct: 119 IGFWDDYVKLKNKKGISIKTKFLLQVLSASLISVLIYYWADIDTILYFPF-FKE---LYV 174

Query: 164 DLGILYYVYMGLLAVFCTNAINILAGINGLEAGQSLVISASIIVFNLVELEGDCRDDHVF 223
           DLG+LY  +   + V   NA+N+  G++GL  G ++  + ++ V  +    G  +     
Sbjct: 175 DLGVLYLPFAVFVIVGSANAVNLTDGLDGLAIGPAMTTATALGV--VAYAVGHSK----I 228

Query: 224 SLYFMIPF--------------FFTTLGLLYHNWYPSRVFVGDTFCYFAGMTFAVVGIL 268
           + Y  IP+                  LG L+ N +P+++F+GD      G + A V +L
Sbjct: 229 AQYLNIPYVPYAGELTVFCFALVGAGLGFLWFNSFPAQMFMGDVGSLSIGASLATVALL 287


>5JNQ-A nrPDB
          Length = 376

 Score = 30.0 bits (66), Expect = 2.1,   Method: Compositional matrix adjust.
 Identities = 37/152 (24%), Positives = 65/152 (42%), Gaps = 17/152 (11%)

Query: 111 LGFADDVLNL-RWRHKLLLPTAASLPLLMV------YFTNFG--NTTIVVPKPFRPILGL 161
           +GF DD + +   R + L P    +   ++      Y  N G   T +++P       G 
Sbjct: 122 IGFLDDYIKIVMKRSEGLKPMQKLVGQFIITGIFAWYLLNSGEVGTDMLIPFTGGFDGGS 181

Query: 162 HLDLGILYYVYMGLLAVFCTNAINILAGINGLEAGQSLVISASIIVFNLVELEGDCRDDH 221
            L LGI +   +  + +   N +N   G++GL        S +I+V   + +     D  
Sbjct: 182 FLSLGIFFVPALFFIMLGTDNGVNFTDGLDGL------CTSVTILVATFLTIVAIGEDMG 235

Query: 222 VFSLYFMIPFFFTTLGLLYHNWYPSRVFVGDT 253
           +  +   +    + LG L  N YP++VF+GDT
Sbjct: 236 ISPITGAV--VGSLLGFLLFNVYPAKVFMGDT 265


Searching..................................................done


Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

6BW5-A nrPDB                                                          678   0.0  
4J72-A nrPDB                                                          177   1e-44

Sequences not found previously or not previously below threshold:

5JNQ-A nrPDB                                                           72   6e-13

>6BW5-A nrPDB
          Length = 417

 Score =  678 bits (1750), Expect = 0.0,   Method: Composition-based stats.
 Identities = 408/408 (100%), Positives = 408/408 (100%)

Query: 1   MWAFSELPMPLLINLIVSLLGFVATVTLIPAFRGHFIAARLCGQDLNKTSRQQIPESQGV 60
           MWAFSELPMPLLINLIVSLLGFVATVTLIPAFRGHFIAARLCGQDLNKTSRQQIPESQGV
Sbjct: 1   MWAFSELPMPLLINLIVSLLGFVATVTLIPAFRGHFIAARLCGQDLNKTSRQQIPESQGV 60

Query: 61  ISGAVFLIILFCFIPFPFLNCFVKEQCKAFPHHEFVALIGALLAICCMIFLGFADDVLNL 120
           ISGAVFLIILFCFIPFPFLNCFVKEQCKAFPHHEFVALIGALLAICCMIFLGFADDVLNL
Sbjct: 61  ISGAVFLIILFCFIPFPFLNCFVKEQCKAFPHHEFVALIGALLAICCMIFLGFADDVLNL 120

Query: 121 RWRHKLLLPTAASLPLLMVYFTNFGNTTIVVPKPFRPILGLHLDLGILYYVYMGLLAVFC 180
           RWRHKLLLPTAASLPLLMVYFTNFGNTTIVVPKPFRPILGLHLDLGILYYVYMGLLAVFC
Sbjct: 121 RWRHKLLLPTAASLPLLMVYFTNFGNTTIVVPKPFRPILGLHLDLGILYYVYMGLLAVFC 180

Query: 181 TNAINILAGINGLEAGQSLVISASIIVFNLVELEGDCRDDHVFSLYFMIPFFFTTLGLLY 240
           TNAINILAGINGLEAGQSLVISASIIVFNLVELEGDCRDDHVFSLYFMIPFFFTTLGLLY
Sbjct: 181 TNAINILAGINGLEAGQSLVISASIIVFNLVELEGDCRDDHVFSLYFMIPFFFTTLGLLY 240

Query: 241 HNWYPSRVFVGDTFCYFAGMTFAVVGILGHFSKTMLLFFMPQVFNFLYSLPQLLHIIPCP 300
           HNWYPSRVFVGDTFCYFAGMTFAVVGILGHFSKTMLLFFMPQVFNFLYSLPQLLHIIPCP
Sbjct: 241 HNWYPSRVFVGDTFCYFAGMTFAVVGILGHFSKTMLLFFMPQVFNFLYSLPQLLHIIPCP 300

Query: 301 RHRIPRLNIKTGKLEMSYSKFKTKSLSFLGTFILKVAESLQLVTVHQSETEDGEFTECNN 360
           RHRIPRLNIKTGKLEMSYSKFKTKSLSFLGTFILKVAESLQLVTVHQSETEDGEFTECNN
Sbjct: 301 RHRIPRLNIKTGKLEMSYSKFKTKSLSFLGTFILKVAESLQLVTVHQSETEDGEFTECNN 360

Query: 361 MTLINLLLKVLGPIHERNLTLLLLLLQILGSAITFSIRYQLVRLFYDV 408
           MTLINLLLKVLGPIHERNLTLLLLLLQILGSAITFSIRYQLVRLFYDV
Sbjct: 361 MTLINLLLKVLGPIHERNLTLLLLLLQILGSAITFSIRYQLVRLFYDV 408


>4J72-A nrPDB
          Length = 365

 Score =  177 bits (448), Expect = 1e-44,   Method: Composition-based stats.
 Identities = 46/188 (24%), Positives = 87/188 (46%), Gaps = 31/188 (16%)

Query: 102 LLAICCMIFLGFADDVLNLRWRHKLLLPT-------AASLPLLMVYFTNFGNTTIVVPKP 154
           LL+      +GF DD + L+ +  + + T       +ASL  +++Y+    +T +  P  
Sbjct: 110 LLSFLSFGTIGFWDDYVKLKNKKGISIKTKFLLQVLSASLISVLIYYWADIDTILYFPF- 168

Query: 155 FRPILGLHLDLGILYYVYMGLLAVFCTNAINILAGINGLEAGQSLVISASIIVFNLVELE 214
           F+    L++DLG+LY  +   + V   NA+N+  G++GL  G ++  + ++ V  +    
Sbjct: 169 FKE---LYVDLGVLYLPFAVFVIVGSANAVNLTDGLDGLAIGPAMTTATALGV--VAYAV 223

Query: 215 GDCRDDHVFSLYFMIPF--------------FFTTLGLLYHNWYPSRVFVGDTFCYFAGM 260
           G  +     + Y  IP+                  LG L+ N +P+++F+GD      G 
Sbjct: 224 GHSK----IAQYLNIPYVPYAGELTVFCFALVGAGLGFLWFNSFPAQMFMGDVGSLSIGA 279

Query: 261 TFAVVGIL 268
           + A V +L
Sbjct: 280 SLATVALL 287


>5JNQ-A nrPDB
          Length = 376

 Score = 71.5 bits (174), Expect = 6e-13,   Method: Composition-based stats.
 Identities = 36/162 (22%), Positives = 63/162 (38%), Gaps = 17/162 (10%)

Query: 111 LGFADDVLNLRWRHKLLLPTAASLPLLMV-------YFTNFGN--TTIVVPKPFRPILGL 161
           +GF DD + +  +    L     L    +       Y  N G   T +++P       G 
Sbjct: 122 IGFLDDYIKIVMKRSEGLKPMQKLVGQFIITGIFAWYLLNSGEVGTDMLIPFTGGFDGGS 181

Query: 162 HLDLGILYYVYMGLLAVFCTNAINILAGINGLEAGQSLVISASIIVFNLVELEGDCRDDH 221
            L LGI +   +  + +   N +N   G++GL    +++++  + +  + E  G      
Sbjct: 182 FLSLGIFFVPALFFIMLGTDNGVNFTDGLDGLCTSVTILVATFLTIVAIGEDMGISPITG 241

Query: 222 VFSLYFMIPFFFTTLGLLYHNWYPSRVFVGDTFCYFAGMTFA 263
                       + LG L  N YP++VF+GDT     G   A
Sbjct: 242 AV--------VGSLLGFLLFNVYPAKVFMGDTGSLALGGFVA 275


  Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
    Posted date:  Jan 3, 2023  9:05 PM
  Number of letters in database: 10,336,785
  Number of sequences in database:  36,641
  
Lambda     K      H
   0.331    0.145    0.432 

Lambda     K      H
   0.267   0.0448    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,474,262
Number of Sequences: 36641
Number of extensions: 858251
Number of successful extensions: 2438
Number of sequences better than 10.0: 43
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 39
Number of HSP's that attempted gapping in prelim test: 2409
Number of HSP's gapped (non-prelim): 53
length of query: 408
length of database: 10,336,785
effective HSP length: 99
effective length of query: 309
effective length of database: 6,709,326
effective search space: 2073181734
effective search space used: 2073181734
T: 11
A: 40
X1: 16 ( 7.6 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 61 (28.0 bits)